LOCUS       DAEPHU010000001       109407 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 01A10CD0081
            SAMN05941466-rid12468953.denovo.001, whole genome shotgun sequence.
ACCESSION   DAEPHU010000001 DAEPHU010000000
VERSION     DAEPHU010000001.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941466
            Sequence Read Archive: SRR6291087
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 109407)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 109407)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068158.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 22:43:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,892
            CDSs (total)                      :: 3,805
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 87
            rRNAs                             :: 8, 1, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 55
            CDSs (without protein)            :: 55
            Pseudo Genes (ambiguous residues) :: 0 of 55
            Pseudo Genes (frameshifted)       :: 21 of 55
            Pseudo Genes (incomplete)         :: 28 of 55
            Pseudo Genes (internal stop)      :: 16 of 55
            Pseudo Genes (multiple problems)  :: 8 of 55
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..109407
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941466-rid12468953.denovo.001"
                     /strain="01A10CD0081"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            complement(164..1768)
                     /locus_tag="KR231_000001"
     CDS             complement(164..1768)
                     /locus_tag="KR231_000001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HBH0002421.1"
                     /translation="MKAKIYYNGNIITMEDSICGDAILIKDKIIKKIGTKEEVFALKN
                     KDTEIIDLQGKTLMPSFIDSHSHLIAFATTLKLVPLEDATSFKDIVKKIQDFKESNNI
                     KKGDWIIGFSYDNNFLEENKHPDKSVLDSASSENPILISHASGHMGVANTLGLKQLGV
                     TNETRDPEGGHIGRVEGSEEPNGYLEENAFFNVASKIKQPSSNEIFNSIEKAQNIYLS
                     YGITTAQEGLMEENQFNILKAMANQNKLKMDVVGYVNLKKSKSVADNNREFIKKYINR
                     FKIGGYKIFLDGSPQGKTAWLSRPYENSDDGYCGYPIYKDEEVEKFIDISLKEKMQLL
                     THCNGDAAADQLIDAFEKVLNLKEQSSENNIRPVMIHAQTVRADQIDDMKVINMIPSY
                     FVAHTYYWGDIHIKNLGEDRAFKISPLKTTIEKGLIYTLHQDTPVIAPNMLETVWCAV
                     NRITKKGIQIGENEKISPLDALKGVTINAAYQYFEEDKKGSIKEGKLANLIILDENPL
                     TIDPMKIKDIKVLQTIREGEVLYSLK"
     gene            2154..3080
                     /locus_tag="KR231_000002"
     CDS             2154..3080
                     /locus_tag="KR231_000002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436788.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbon-nitrogen hydrolase family protein"
                     /protein_id="HBH0002422.1"
                     /translation="MSKENKNVRIAVVQASPVIMDLEKTVEKALGLIKEAGRKGANIV
                     VFPEAFIPAYPRGLSFGFVVGSRTMEGREDWKRYYDNSVPVPSATTDLLGKAAQEAGV
                     YLSMGITERDGNDINCTLYCTNLFFSPEGKLIGKHRKLKPTGTERCIWGEGDGSTLTV
                     VDTPYGKMGSLICWENYMPLARTALYAKGVKLYIAPTADSREEWQATMKHIALEGRCF
                     VIGCNQYVEKNTYPTDLNYYKELDAEPEIMCPGGSCIVDPFGKYVAGPIFNKEEMLIA
                     DLDLEKIVLSRLDFDSEGHYSRPDVFELIVHE"
     gene            complement(3200..4198)
                     /locus_tag="KR231_000003"
     CDS             complement(3200..4198)
                     /locus_tag="KR231_000003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhdH/YhfP family quinone oxidoreductase"
                     /protein_id="HBH0002423.1"
                     /translation="MNKKFKSLYITEEEGNFRRNIVEREVDTLPEGEVLIKVKYSSLN
                     YKDALSANGNKGVTRKYPHTPGIDASGIVESSSCDDFKIGEEVLVTGYDLGMNTSGGF
                     SEYIRVPSSWVVKLPKNLSLKEAMDYGTAGFTAALSVYKFIDSVDKNMGDVLVTGGTG
                     GVAVIATKILIKLGYSVVVSTGKLEEQKEVLLNLGVKDVIHRSEVDDNSGRPLLRPRW
                     AGVIDTVGGNTLATAIKTTNYCGAVTTCGNAGGVDFTSSVYPFILKGITLYGIDSVDC
                     PMNLRLKIWDLLSNEWKLDDLDDMVNVVSLEELNDSIDSIMAGKHVGRTVVDLEKI"
     gene            4302..4739
                     /locus_tag="KR231_000004"
     CDS             4302..4739
                     /locus_tag="KR231_000004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HBH0002424.1"
                     /translation="MEDKYIVHFISKTKASMIKFIENKLSKNGLGELIPTHGNILTAL
                     YENNGILTMKEIAAKIGKDKSTVTVLVNKLINLGYLERQKCTNDKRITYIKLTKKALL
                     IEDTFNSISTQVKETAYHNITENEKQEFLRILKKINDNFKNAD"
     gene            4825..5412
                     /locus_tag="KR231_000005"
     CDS             4825..5412
                     /locus_tag="KR231_000005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rubrerythrin family protein"
                     /protein_id="HBH0002425.1"
                     /translation="MNLKDSKTKENLLRAFAGESQARNRYNISASVAKKEGLYIIESL
                     FNYTADQEKSHAKQFFSKLKEFAGENISISGAYPVDLYDKTAQHLKAAQHNELQEWDD
                     VYKNFGKTAREEGFESIAKLFENIAEIEKVHGDRFGRYATDLEEGTLFRRNEDIQWIC
                     THCGHIHIGKEAPKACPVCLHPQGYFLDFKNSLFE"
     gene            complement(5712..6332)
                     /locus_tag="KR231_000006"
     CDS             complement(5712..6332)
                     /locus_tag="KR231_000006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhbD family protein"
                     /protein_id="HBH0002426.1"
                     /translation="MEELISKKDLLSKTNISYGQLYRWKRKNIIPEEWFIKKSAFTGQ
                     ETFFPRDKILERIELILSMKEETSLDDIANMFMKKDINKEFDIDFILSKEVICNYTKE
                     IFQNLYKKEQSIGKKELLILSIIEKFLVKSIITFEELKLIVNIIEENFTSIYNESGKI
                     YLFRKFGVPFVVGCLDYKKVKFEKDVVKIIEIDLTKEINDISIKLS"
     gene            complement(6340..7107)
                     /locus_tag="KR231_000007"
     CDS             complement(6340..7107)
                     /locus_tag="KR231_000007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polymer-forming cytoskeletal protein"
                     /protein_id="HBH0002427.1"
                     /translation="MEKGSIKILGEGFISSGEYENIKIVGSSKSKGNVKSNEVKVLGD
                     AKFEGDINIKNFVVNGKTIIRGNLKAERVRVNGQLNIEGDAEIDDLVITAQQKVDGKL
                     KCNNVTIRGQLSVNENMYAQDIKIYGEMRNKSNIECEDIKVYGAIKCDGLLNGENIYV
                     YSGGGSYCKEIGATNIKIGRSKDAFSLIKIINIFSGKFKCNLIEGDTIELEDASIKDI
                     RGKSISLVDNCDVGNIEYSDNLSVSDNSTVKNSIKVG"
     gene            complement(7148..7969)
                     /locus_tag="KR231_000008"
     CDS             complement(7148..7969)
                     /locus_tag="KR231_000008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0002428.1"
                     /translation="MNEELSSLRFDGVGKCKGGIFDNVNISGTGKIEGSVKCSKFDSS
                     GSAKVFGTTECNEFFTSGLSKVEGNILASKVEISGLLRCTGNINSVEIDTSGIINVEG
                     SIKSDIIHGEGYLKANENIDCENINLSGILECNGFLNCEEVNISLNGTSNFNEVGASS
                     INIKKGHGDYCKKFRMLEKKHINFEKVSSNLISLGLLSIRKYTESKLFANIIEADEIS
                     LENSEVKVVRGKNIKIGKGCYVESLEYSESIEIDEDSIVGEIKNISEKIKLKKDK"
     gene            complement(8328..10238)
                     /gene="phnW"
                     /locus_tag="KR231_000009"
     CDS             complement(8328..10238)
                     /gene="phnW"
                     /locus_tag="KR231_000009"
                     /EC_number="2.6.1.37"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-aminoethylphosphonate--pyruvate transaminase"
                     /protein_id="HBH0002429.1"
                     /translation="MKKIYGEKIKAVVFDWAGTTVDYGCFAPLNVFIEIFKRRGIDVT
                     MEEARKPMGKLKIDHIREMCEMDRIKNIWSDKFGKVPTEDDVNELYAEFEPMLFETLE
                     EYTTPIPHVVETIEKLRKNGLKIGSTTGYTREMMNIVEPNAAKKGYSPDFLVTPSEVS
                     QGRPYPWMCYKNAEALGVSPMSSMVKVGDTISDVKEGVNAGMWSVAVIKGSSELGLTQ
                     EEVENMDKEELKAKMSIVSKKFKEAGAHFVIETMAELEDILIKIENETIKSDFVPEND
                     YILLTPGPLSTTKSVRASMLKDWCTWDVEYNNLVQDVRRRLVSLATQNTDKYTSVLMQ
                     GSGTFSVEAIIGSTISKDGKLLVIANGAYGKRMKDICNYLNIQFVDCTFKDIEAVDLN
                     VVENLLKENKDITHISMVHCETTTGRLNPIQEVGKLAKEYNKIYIVDAMSSFGGIEID
                     VEDFNIDFLVSSSNKCIQGVPGFGFIIANKEKLSKCKGIAKSLSLDVYAQWETMEKNN
                     GKWRFTSPTHVVRAFYQALLELEEEGSVEKRYARYKENQFTIASRLKSLGFDTLVNDN
                     AQSPVITTFLYPKNAKFEFMEFYTYLKDNGFVIYPGKLTDIDTFRIGSIGEVYPTDME
                     RLADVIEKFINR"
     gene            complement(10517..11302)
                     /locus_tag="KR231_000010"
     CDS             complement(10517..11302)
                     /locus_tag="KR231_000010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HBH0002430.1"
                     /translation="MSLNSIDRKKEILKLLDSKGKVNTKELVKRLEVSSETIRRYLEE
                     LENENKLKKVYGGAIKINYGVIEPEHIKRNNTNLDKKQSIAKYAAKFVNDNESIIIDE
                     GTTNLQIVDYIISVNNLKIITNSYPVLSKLISYENQGLFDGEVIFIGGKVNLKHQRTA
                     CPISIDAMKNLYVDKAFISSEGILDSFGISSIDQNKALLSKAYIKNSKESFVLCDSSK
                     IGIASMYKIADLEELDFVICDVEPPNEWKDKLNEINITWIEAK"
     gene            complement(11519..11749)
                     /gene="dltC"
                     /locus_tag="KR231_000011"
     CDS             complement(11519..11749)
                     /gene="dltC"
                     /locus_tag="KR231_000011"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltC"
                     /protein_id="HBH0002431.1"
                     /translation="MQETVIEIFEDVLGTDEIREDLDLNLFETELLDSLAIIEVLLEI
                     ENRLGIELQPTDLERKDMSTVNNLVKFLETRK"
     gene            complement(11768..12916)
                     /gene="dltB"
                     /locus_tag="KR231_000012"
     CDS             complement(11768..12916)
                     /gene="dltB"
                     /locus_tag="KR231_000012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltB"
                     /protein_id="HBH0002432.1"
                     /translation="MIFSQYGDYFYLYILLLTSIPAVILGLMGKNIKYYGMLASLFMI
                     FLIVGIDVQLKYLVIFIILEVIIVKGYEYVRRKTKNKYIYWGFLFASMLPIIINKISP
                     VTSFGIIGFIGISYLNFRTIQMVIEIYDGAIKEVKISKMLYFMLFFPTLSSGPIDRSR
                     RFEQDLEKQISRKEYIEEYLLPGIKNIVMGVGYKFVIAFLINTYWVSRIPKDMSFINI
                     LSYMYAYSLYLFFDFAGYSLFAIGTGYIFGIQVPINFDKPFISKDMKEFWTRWHISLS
                     RWFGDYIFSRFVMSSMRKKRFKKRTTAAHVAQMITMITMGFWHGLTWYYVAYGVYQGL
                     ALVLTDIYQRKSKFYKKHKKDKWFERVQIFITFHIVCFGLLIFSGYLA"
     gene            complement(12916..14430)
                     /locus_tag="KR231_000013"
     CDS             complement(12916..14430)
                     /locus_tag="KR231_000013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893738.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase"
                     /protein_id="HBH0002433.1"
                     /translation="MKIIEGIKKYSNTDRTALMCNGDKLSYKDLNEYSDAISVFLKDV
                     YKEEDTPIVIYGNKENMIMACMIGALKSGRAYVPLDISFPIDRVFEVTKEIKPKVLFN
                     FSDERNFGDINVIDMDKLNYIINEYQGKSLDKENWVKDDENAYILFTSGSTGKPKGVQ
                     ISSNNLDSFSDWISPYLNIDGSEKVIMNQPAYSFDLSVTTIYPGLIHGATLFSISKDV
                     LADYKELFRQFSISDIAVWVSTPSFAGVCITEKEFNSKMLPNLESMIFIGEALSKNLT
                     KELMSRFPNTRIINGYGPTEATVGVSVNDMTQKAIDDEKSLPVGYPMSNCKIKILDED
                     GNELKENEKGEIIIIGPSVSKGYFNNKEKTDEVFFYDEIDGVKWRAYKTGDMGYLLDG
                     NIYYCGRKDFQIKLNGFRIEIEDIENNLRKVHNVKNAVVLPVYKDEKIAYLKGIVELN
                     EKNDLSNIKNGMIIKKELGKYIPSYMIPRNISIISEFPTNINGKIDRKKLMEEI"
     gene            complement(14551..15741)
                     /gene="dltD"
                     /locus_tag="KR231_000014"
     CDS             complement(14551..15741)
                     /gene="dltD"
                     /locus_tag="KR231_000014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltD"
                     /protein_id="HBH0002434.1"
                     /translation="MRKLIYFITPFIIGVVFLFGLDKFLDSKTDELLREKNLLPIMDD
                     TLSDIKDKGVTANNHFLREKDIMILGSSELSNSTKQHPKYYFNTNRSKNKVFAIGRAY
                     TQTLQDAAILGSMNPNIDNKKVVLLISMQWFMEKDGVTSHHYQSRFSPIQFYRFLDNP
                     KISKQNKIEYAKKSSKLLWGSDEYKAEALYAKLYEPKTFPEKAEKVLLEPYFQGRKYC
                     IALKEKGILYKRLIKLDKKRATKRKRPINWSYERKKAIEDAKKRVGKNPLNIDKYYYK
                     EHFKDGIEQYKGRDKDVNLLTSKEFENYKLMLNVCTDLGIKPVVVLIPSMDKFYNLTG
                     ISEKERNQYYDKAQKIAESKGFEVLNLKDKGSDKYYLRDVMHLGTKGWVDVCERLFKI
                     FKEQ"
     gene            complement(16029..17048)
                     /locus_tag="KR231_000015"
     CDS             complement(16029..17048)
                     /locus_tag="KR231_000015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HBH0002435.1"
                     /translation="MMGKIRFGIVGTSNIANIFLRAASRVKDFELVAVYSRNLEKARE
                     FGTLYGASIFFDDLEQMAKSKDIDAVYIASPNALHSKQTITCLKHKKHVLCEKSLASN
                     LKEVKSMIKTAKDNNVLLMEAMRITCVPNFKAVKENLYKIGKIRRFFGSYCQYSSRYD
                     KYKNGIIENAFKKELSNGALMDIGVYCIHPMVNLFGAPKTVKAVSHILQTGVDGEGSA
                     VFQYDDMDAIIQYSKVADSYIPSEIQGEEGSIIIEKLNLFEKAIIKYRDGREEDISIP
                     KEKAEEKPREIEGMYYELVEFISLINNNKIESNINSHENSIIVMEIMDEIRRQSSIVY
                     PADSI"
     gene            complement(17224..17763)
                     /locus_tag="KR231_000016"
     CDS             complement(17224..17763)
                     /locus_tag="KR231_000016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative ABC transporter permease"
                     /protein_id="HBH0002436.1"
                     /translation="MDNVGSLLYFLFNFFLYGFIGWIIENLYSYYKQGHFQEDGFLNG
                     PFKPMYAIAMSIIIEVSRFIDPNNIFALLLLCLVVPTVVEYITGILMKVYFNKVYWDY
                     SDYKYNSRGIVCLKFSVYWTILTFIGVRYFQVYIVDSLYSLIIPYWPIVVTILLVTLF
                     VDEILTIKFLRGNKDIVER"
     gene            complement(17864..18544)
                     /locus_tag="KR231_000017"
     CDS             complement(17864..18544)
                     /locus_tag="KR231_000017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family phosphatase"
                     /protein_id="HBH0002437.1"
                     /translation="MQKVEGIIFDMDGVLFDSERISLEFWMETFEKYGYTMTKEIYTS
                     VMGRNRKGIIEGLTDIYDSSVPIIDLYDEKTKNMIEFMERKGAPIKLGVNELISFLKE
                     NGYKMAVATSTKRERAVKRLAKANLKDYFDAIVCGDDVVNSKPNPEIFLKAAKKINVN
                     PKNCIVIEDSPMGVEAAYNGGIRCINVPDLKEPDEQIKSQSHKILENLLEVREYLKSL
                     NSKECHNL"
     gene            complement(18573..19862)
                     /locus_tag="KR231_000018"
     CDS             complement(18573..19862)
                     /locus_tag="KR231_000018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898029.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyC/CorC family transporter"
                     /protein_id="HBH0002438.1"
                     /translation="MRELLKVTLIVMLVLINAFFVACEFAMVKLRSSRIDTMITEGNN
                     NAKRCKIIKDNLNSYLSACQLGITLCSLALGWMGESTVKELILPIVSVFNLSESIIYT
                     ISISISFLIITMMEVVIGELVPKALALYNTEKIMLSTSFLLVGFYKLTYPIIYFFNLS
                     TDLFLKPFGYSQADEVDEPHTGDEIRLLVEESYKSGLIDESEQRLVDNIFEFEEKKIR
                     EIMVPRTDMVCIYESDSEEKILAILKEEGVTRYPVCRKNKDDILGFVHIRDLYNQKIN
                     ENKIELEEILRDIIYISENLTIDKALERIRKEKLQLAIVVDEYGGTSGVVTIEDILEE
                     IVGEIQDEFDKEETHIKKIGAGSYLVDGTESINYINKYFGLDIEHDGFDSIGGWISYM
                     LGSNIKVNQSVTFENYNFTILELDKLRVVKLIIKSVI"
     gene            complement(20311..21912)
                     /locus_tag="KR231_000019"
     CDS             complement(20311..21912)
                     /locus_tag="KR231_000019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase family protein"
                     /protein_id="HBH0002439.1"
                     /translation="MIYDLILKNGFIIGGTGNPGFYGDIAIKDNLIAKIDSKINSNTN
                     KEIDCCGKVITPGFIDPHVHEEIVAILDGKFEKFLKQGVTTTINGNCGHSITPYSSEN
                     VYEYMYKNGLLLEEEKKYLIDKNKCWNNFTEYCDLISKSGISVNMGFLLGHGTIRWSV
                     MGGSKDRPPTEKEKNEITDIINDGMKSGAFGISTGLAYIPSKYADIDELVDIAKQIKE
                     HDGIYTSHIRDYIGRYNAVKEAIEVGQKSGARVQVSHLSPVEIEAFDEILKARYNGVE
                     IMVDTVPRSSGHCMKKKRVIQFIMAISSSLFELGINGVMDALRNEEGRTLILKEAFIL
                     GDRGSIILLNTKDINMEKKSIREIATQKGIDEDKLLLDLLLDGDEELIFCLGGMYRAD
                     FPDKLHDDKIIDNPFVMVGSDCLFSVGGDMSWFELQRRGAFPIFFNMYRKSGVRLEEI
                     VRRVTSLPARQFKIKNRGILKEGLIADIAVIDMDNYSYSRSEDIDFSKPQLLANGVEY
                     VIVNGKIALENGEITENKCGEVLKR"
     gene            complement(22023..22700)
                     /locus_tag="KR231_000020"
     CDS             complement(22023..22700)
                     /locus_tag="KR231_000020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426728.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0002440.1"
                     /translation="MSKVKSIYNEEYLPFKIRYGRLTLSLGIIAALVPGIILSFGFGI
                     MPPISALLASTMAIVSMSAPNYIIEPVSYSPILGIPGTYMSFLSGNISNMRLPCSIAA
                     QKAAEVESGTEEGSIISTIGIAVSILVNISILTIGVILGGSVLSKIPAEVVEKLNLIL
                     PALFGSVFGQVFLQDKKLGLVAIVISVLTIILSKQGIIPQSLVVLICVFGTMLIARAM
                     YKDKLSD"
     gene            complement(22713..23408)
                     /locus_tag="KR231_000021"
     CDS             complement(22713..23408)
                     /locus_tag="KR231_000021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5058 family protein"
                     /protein_id="HBH0002441.1"
                     /translation="MDYLKLANHPLLWIASTVAVSIVVVQSLIFAIKSCKVGKTMGIT
                     DKQIKSAVKSSAISAIGPSMTIFAGMVSLIVTMGGPIAWMRLSFIGSVIFESMSAGFG
                     TDALGITLGSPEMTKLAFTNAVWTMILGSLGWIIFTLLFGHKLDKITNVISSGKKSFI
                     PIISLGAMLGSFAYLNADRVLRFDNGTIACISGMAIMVILCMLEKKKNIKWLREWGLT
                     ISMFSGMIIASVI"
     gene            complement(23460..24659)
                     /locus_tag="KR231_000022"
     CDS             complement(23460..24659)
                     /locus_tag="KR231_000022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase"
                     /protein_id="HBH0002442.1"
                     /translation="MKSAYKGYEAYSYLEKGKDISSIEMCKGDKRVKEYLIELDDIQE
                     AKVKSIVDEKIFISLHEHPVLFPEHLERDIFEYNREGKQRCAYEALSRGYYDAIFDNL
                     MDGVCTITSNSGWKWDDILIDLGMRLCDLAHQDFVIKCEKVEDIYRAKSEGKVALIPT
                     LEGAAPIENELDRIDILYGFGIRLMGITYSESNALGSGLKEEKDGGLTNFGKKAVERM
                     NKIGMAIDCSHVGVQTTLDVIEYSKDPIILSHVGARSLWNTKRLTPDEVLIACAKKGG
                     VIGVEAAPHTTITEKNKEHSIESFMEHFEYIKNLVGIDHVAFGPDTVYGDHVKLHSVL
                     AAKFDIKKITGTKEHPKVEYVKGLENPTETSKNIVRYLVKHGYSDEEIEKVLGGNILR
                     VLKQVWK"
     gene            complement(24920..26965)
                     /locus_tag="KR231_000023"
     CDS             complement(24920..26965)
                     /locus_tag="KR231_000023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893739.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HBH0002443.1"
                     /translation="MKKHNILFVSTDDKINIDISKQLENIFGEFCNIDNLVYVNRINI
                     ELSSYELVVCSDNDIKEYIHNNIDKNIPIVIVHRTINIENINQIISIENDSDVMVIDA
                     YKESADETAKIIRKLGLIHINLIPYYPGCDKSKCEIGIITGSRNSIPQNIKQIIDIGD
                     KVIDINTVIEIFTKLNISIDKLHIIKEKYNEDTVSGYRYYTTMNKTMKSFLEIIDEGI
                     ASVDKLGKFIYCNKVFSNLVGIDQNEIISNNFMDLFSDKVVKKIFFQEDEVNDEVVNL
                     NNKKLIINKVNVYENNERIKSIISIKNISAIQVLEDKIQNKLQSKGFVSKYTFESVVG
                     ESKIIKEKINIARKIATTDFSVLILGENGTGKEIFAQAIHNESLRKNKPFVAVNLSSL
                     SDTLIESELFGYDEGSFTGAIKGGKMGIFERAHTGTIFLDEIGDISLDVQQRLLRVLQ
                     EKEVMRMGGSKIIPIDVRIIAATNKDLKKKIKEGSFREDLYYRINVLHIEIPRLRERK
                     EDIPLISKYFLDEINSNKCFTEESMQALTLYEWPGNVRELKNLIYYIDTIVEEDRVDY
                     EHLPEQFRFEKNNTLVNENFDSIILDFKQSNFFEESICILTSIETWNNKNILLGRNKL
                     QEILKEKDIVLSVDQIRKRIDKLKSHGLLLSGVKKQGSFITDEGKNFISYVKIKGVI"
     gene            complement(27376..28185)
                     /locus_tag="KR231_000024"
     CDS             complement(27376..28185)
                     /locus_tag="KR231_000024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HBH0002444.1"
                     /translation="MYYVYVNDINIAVYDLNPSAKKTVLFIHGWPLGHKIFEYQTNIL
                     PKLGYRTVSIDLRGFGKSDATSGGYTYSQLADDIYKVVHAIGLKDFTLVGFSMGGAIV
                     LRYMSLFNGYGVSKLVLAAAAAPSFVQRPPEFPYGMTREDVNKLIAQACTDRPEMVTD
                     FGEKVFASNPPESFRRWFNDIGFSASGIGTIGTAVSLRDEELFNDLKCVRVPTGIFHG
                     KLDEICPYEFAVFMNEKIEDSILYTFEYSGHAIFYDELKLFNQKFLQFLEE"
     gene            complement(28269..28802)
                     /locus_tag="KR231_000025"
     CDS             complement(28269..28802)
                     /locus_tag="KR231_000025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="manganese catalase family protein"
                     /protein_id="HBH0002445.1"
                     /translation="MSDAHYDMHKRNGYSSDEPYPEIKVLGPNKYYAELLMDDYAGVS
                     SEFTSVNQYLYHNFDLDETHRELSEMWINISITEMLHMEILAKTIRLLGGNPVYRGST
                     SSCGAYWNGGFVCYGNSICNRLKLDLHLEHVAINNYYKDISLIEDPYIKAILNRIILD
                     EKLHVSLFEKAIEKYCK"
     gene            complement(28952..30301)
                     /locus_tag="KR231_000026"
     CDS             complement(28952..30301)
                     /locus_tag="KR231_000026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TldD/PmbA family protein"
                     /protein_id="HBH0002446.1"
                     /translation="MELKNFKDILFKKALSEGFEEYEIYYYTGENLSINIYEGEVEKY
                     NLDKSFGLSFRGKVNGKIGYSYTEILDDKAVDMLIKNVKDGVNTIENEDVQFIYEGDK
                     HYNDVKTYSKELENLEADKLIDLALEMERETKAYSDKVVNLSKCTISYSVSSNGISNT
                     KGLNLSNKTNMLIGFVVPIIEDNGQKYDGIGYNIANSIEEIKPCEIAKLGVDNALSKV
                     GGKSIPSGKYKTILLNEAMVSLLSTFSGIFNADSAQKGLSLLKNREGDMIASPIVTIV
                     DDPLLENGMASTPFDDEGVATFKKEVVLNGKLITLLHNLKTANKAGVKTTGNGIKSSY
                     SSPISIYPTNFYIEKGDKSLDEIIKDIDEGLMVTSFAGLHSGANSVTGDFSLAAKGFY
                     IKEGKKVFPVEQITVAGNYFDLLKDIEAIGEDLEFPMSSIGSPSVVIKELSVAGKDE"
     gene            complement(30313..31695)
                     /locus_tag="KR231_000027"
     CDS             complement(30313..31695)
                     /locus_tag="KR231_000027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011967718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TldD/PmbA family protein"
                     /protein_id="HBH0002447.1"
                     /translation="MLSKNIASKVLEKCLITGGDFAEIFEEDTINNSISLIDNKVENA
                     IGGRNYGIGIRIFKGLKSIYAYTSDNSLNSLLDVAYKAAVALGKLEDGKSVILNDSIK
                     INNIHNIKIYPNSIGNKDKVSVMKVAYKSAKEFSNDISQVSVSYLDKDQKILIANTEG
                     IYVEDRRIRTRLGISSIASKGNENQTGFEGPGGCKGFEIFEEIDPEYYAKESARVAHT
                     MLHAKNCPAGNMMVAIDNGFGGVIFHEACGHSLEATSVAKGNSVFADKLGQQIASTKI
                     TAIDDGTIPNYWGSMNIDDEGNPTQKNILIENGILKSYMIDKLNGRRMGMNPTGSSRR
                     QNYKFAPTSRMTNTYIAAGEDRPEDIIKSIPDGLYAKKMGGGSVNPVTGEFNFAVSEG
                     YLIKNGEIQEPVRGASLIGKGSDILMNIDMVGNNVKQAQGMCGSSSGSIPTNVGQPMI
                     RVKEITVGGR"
     gene            31939..33153
                     /locus_tag="KR231_000028"
     CDS             31939..33153
                     /locus_tag="KR231_000028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-binding oxidoreductase"
                     /protein_id="HBH0002448.1"
                     /translation="MNQEYVKGNPIFTNINKVPRQFPYLTDDIDTDVIIVGGGVTGCI
                     CAYYLAKNNIKSVILEKGRIAHGSTSVTTSLLQYELDDNLIDLTEVMTLKDALKAYNL
                     CTSALEELDTFIELYGNKCDYAKRDTLLYTANKLEVKAIKEEYNLRKENGFDVEYIDE
                     STNPFNFDLKSGLIAKNGGRELDPYKYSHHLIDVSLKNGLQVYENTEVKKVDLSNDKV
                     TAEVSYGYKVHGKKLIVATGYNTSLFTKRNFATKSNTFNIATKPLKNIASWKNNILIR
                     DNCDPYNYLRTTKDNRLIIGGEDVSFDDIENETLANEKYDILEQRLKSMFKDIKDIEV
                     EYKYCGCFASTLDNLGFIGPDNKNNNLWYCLGYGANGILFAILGGIMLSELYLGKQNK
                     NMKLFKVDRFDK"
     gene            33330..35243
                     /locus_tag="KR231_000029"
     CDS             33330..35243
                     /locus_tag="KR231_000029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HBH0002449.1"
                     /translation="MKYGGIIMKEILVIAPTKGTYEKSIHIVKKNKYTNIDVVFGNLK
                     EGIPLAEKSINHGTRIIISRGGTYNMLKATYNIPIVEIKVDAYDIIKSYKEVKNSNEP
                     FGIIGFNNVIYGFDIIEEILNKKITMIEIEKEEEIYDAIEKYRKKGINTYIGDTTVAH
                     IVKRLNCKGILIESREENILRAIQQAEQILEATKDEQKRRLQIEAMTDFVHDGIITVD
                     KNFKITLFNKSAEKIFGIKKENALYHNVVDVIPNTVLPQVVETMEPQIGEIQNIGSTK
                     IITNRVPIIVDGQIQGAVSTFQDSKEISSFEHTIRRSLLSKGLSAKYTFDDIIHASEK
                     TKDCIELAKKYACYDTPMIITGESGVGKELFCQSIHNYSKRKNAPFVAVNCAAIPPSL
                     IESEFFGYEEGSFTGARKKGKAGVFELAHEGTIFLDEISEIPLELQGRLLRVLQEKQV
                     MRIGGDKVIPIDVKIICASNKDLKNMMRNGLFRQDLYFRINILTLYLPSLKERKEDII
                     KLSEFFIHKYSSKYNKTPLIITPNIKKALLEREYEGNIRELEGMMERAVIVESFDSIL
                     LEKVSNEYTNNIVDKDNSDFECSNLDLKTLEKKYIYKIYNENNRNTTKTCEILKITRS
                     TLWRKLKEIEDDV"
     gene            35514..36488
                     /locus_tag="KR231_000030"
     CDS             35514..36488
                     /locus_tag="KR231_000030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426739.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-keto-3-deoxygluconate permease"
                     /protein_id="HBH0002450.1"
                     /translation="MHILKSVKKIPGGLMVCPLLLGALFNTVCPQALEIGGFTTSLFK
                     TGAMSILALFCLCNGAQINIRQAGKPLTKGIVLTATKFIIGAVLGIIVSKFIGPKGII
                     GITPLAIVATMTNSNGGLFAALAGEYGDSTDVGAISILSLNDGPFFTMLAFGVTGLAN
                     VPIIALFAALIPILLGFILGNLDEDIREFLAPGTTLLIPFFAFPLGAALNFNQIITAG
                     LPGVVLGLGVTIITGMGGYFVMKLIRAEHPAVGAATGTTAGNAAGTPEALAAIDPTLA
                     TIAAVSTVQVAAAIIVTAICCPMLVSYLDKREKKKKSIFKTNKNIEVN"
     gene            36509..36784
                     /locus_tag="KR231_000031"
     CDS             36509..36784
                     /locus_tag="KR231_000031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UxaA family hydrolase"
                     /protein_id="HBH0002451.1"
                     /translation="MNAIIHANEKDNLVTCVRPLVKGEKVSIDGKSYIVNDNIPVFHK
                     MATEDVKKGDVVYKYGEIIGIATVDIKTGDYVHVHNIESTRGRGDKK"
     gene            36797..37960
                     /locus_tag="KR231_000032"
     CDS             36797..37960
                     /locus_tag="KR231_000032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898047.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UxaA family hydrolase"
                     /protein_id="HBH0002452.1"
                     /translation="MKLMGYLRENGQFGIRNHVLIIPTSVCSSETATRIASLVPGAIA
                     IPHQHGCCQIGSDIELTAKTLIGFGKNPNVAAVLVVGLGCDGIQAKELASEIATTGKK
                     VDYVVIQECGGTLKTVSKGAEIVSKMAREVSKEVRVEFGMSEITLALECGGSDPTSGI
                     ASNPSIGVASNLLVDEGGSSILSETTEVIGAEHLLATRFEDEEMKDKFLKFVSDVEKR
                     AIAMGEDLRSGQPTPGNKTGGLSTIEEKSLGCMYKAGNKPFKGALEYADIVPPDKKGL
                     YFMDTPGQDIDSITGMVAGGAQIVIFSTGRGTPTGSPISPVIKITGNSDTYNKMPDNI
                     DINAGRIITDGAKIADIGQEIFNEIIEVCNGKHTKAESLGHREFGIYRISSTF"
     gene            38297..40576
                     /locus_tag="KR231_000033"
     CDS             38297..40576
                     /locus_tag="KR231_000033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439637.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GGDEF domain-containing protein"
                     /protein_id="HBH0002453.1"
                     /translation="MNFENTKNKKIIATLLLTLLLIVSLTCVTFIMNLNKVTHNETER
                     YLVEVSQGISTTINVKCKSIFRTLYSMGDTYFEINDSEKEVNRYLSKKLKLFEFDWLG
                     IIDSNGNFVSALKDTGNVKGQDFYRKALQGKETITPVKSQSGTYGILYSVPLYNGDKI
                     VGAVAAWNTIDTMRNLLSVESFHGEGFSQIIDQDGNFIVSSANKNAPKNVVNFFDMIK
                     HQGKQVDKNKLEEMKINLKKNKTGSMYYTLNDGISKAMHYLPLQEENLYLLSIVPTKT
                     ASAQFDLLLKKAIFINILIVILFLLLIILIMFINQKNRAQLIKIAYVDSVTKGYSKAR
                     FDIEAKKIIQSSSSESYSLVSINIQKFKLINDSFGSEAGDKTLKYIHDVISNYLEPGE
                     LLCRVSNDQFNVLIKTIPQKEILKYIENITNDINSFNKNEECKYFIALSIGVYKIDDP
                     NLPLVSIQDRANVARKNNKGNIGNHPLYTCVFYSDLERLKMIKEKEMENRMEEALNNN
                     EFIVYLQPKISLKDNTIVGAEALVRWQDPNKGLIPPDEFIPFFEKNGFITKLDHYVFE
                     KVCSMIRKWIDNGETPIPVSVNFSRANLNNIDFLEKYRMLRNKYNIPAKLLEIELTET
                     LVFENLQKLINIIDQIHEEGFQCSLDDFGSGYSSLNMLKEIKVDTLKLDRAFFSSPNA
                     DNIAENHVIESIVNLAKKLNMNSISEGVETILQMDYLKKINCDMIQGYVFSKPLPQEI
                     FEKMTFGKKLEETSMDSSV"
     gene            complement(40671..42011)
                     /locus_tag="KR231_000034"
     CDS             complement(40671..42011)
                     /locus_tag="KR231_000034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HBH0002454.1"
                     /translation="MENQEALRHEKIWILLFRYSIPAIIAMMVTSLYNVVDRAFIGSM
                     EGIGSIAIAGLGVTMPVFTLIIAFGMLVSVGASTRLSIKLGERNREEAEKILGNALTL
                     SIIISLIITILGLVFLEEILFILGASKDSIFYAKDYMSVILVGSIFNLVAFSLNNAIR
                     AEGNPKLAARTMIVGCVLNLILDPIFIFVFNLGIKGAAIATVLCQIVVFFWVIHYFIR
                     GKSNLKLKKCNLKLNKDIVKKVFAIGMTPFAMEVAISITHMFTNNSLKVYGGDLAIGA
                     MTALTSILLMFMMPVFGLNQGMQTIISYNYGAKQYERAKKTLILSIIVSVVILSFGFL
                     VVQVFPEVFVGIFNKDSDLMDIAVRGISLNLITLPIMGISIVGPVYFQCISKVKHSMF
                     LTLLRQFILFIPLIIVLPIQFNLDGVWLAQPVADFIAMIIVLLFLKREFKTSRV"
     gene            complement(42023..42805)
                     /locus_tag="KR231_000035"
     CDS             complement(42023..42805)
                     /locus_tag="KR231_000035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004460318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH0002455.1"
                     /translation="MNCINTKNLNVSYGNTDIIKNLNLNIPKGKITTIIGANGCGKST
                     ILKTIGRIISPNSGKIYINGEDIYKKKSKEIAKDMAVLPQSPQAPSGLTVSELISYGR
                     FPHKSGFGNSSKEDREIVNWSLEVTGIAEFKDRNMEDLSGGQRQRAWIAMALAQETDI
                     LLLDEPTTYLDLAHQLEILKLLDELNKKQGRTIVMVIHELNNAARFADHMIGIKKGKI
                     VCEGDAYDVMTKDNLKELFNIDAEIATDPRTNKPICITYDMV"
     gene            complement(42820..43842)
                     /locus_tag="KR231_000036"
     CDS             complement(42820..43842)
                     /locus_tag="KR231_000036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HBH0002456.1"
                     /translation="MKNIIKINSKTLLVISILMVLIFITFLLSLNMGSFSIEPMDVIK
                     TFLGQGQRNHEIAIFKLRLPRIVIALLVGSALSTAGVILQGVTKNDLADSGILGINSG
                     AALFVVVYIYLMNGNVYEGMSNLTVFTMPIVALIGALFGAFLIYSLAWKGGINSSRLL
                     LIGIGVNIAFTSILTIFQLKFTTQEFNRVMAWTSGSIWGTSWKYVIAVLPFIVIFMGI
                     TIYKSKYIDVLNLGDEVSISLGVDVEKQRRRLIIYAVILSGVSTAVAGSISFLGLIAP
                     HIGRKIIGPKHKRLIPVSALIGTLLLLIADTISRNLLAPIEIPVGIVVSIIGVPYFIY
                     LMLVND"
     gene            complement(43848..44861)
                     /locus_tag="KR231_000037"
     CDS             complement(43848..44861)
                     /locus_tag="KR231_000037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HBH0002457.1"
                     /translation="MTKLSKKNITYLLILVSIVVLVFGIVLSITIGAKDMNLSTVIDS
                     LIKMEDGINMRIVKDVRLPRAIAAALVGGFLAVSGAIMQGITRNPIAEPSVIGITQGA
                     TFAISISLVLQKKLPQLIHGSFSVMMFAFIGASISGLFIYFISSKSRGRVNNVKLALA
                     GVALGTLLISLASAISMYFNLSQQLSFWISGGLVGVKWEGIKLLFVAGGIGFILAIIM
                     APRITILSLGEEVAIGLGQKTKFVRFICIVLVILMTGASVSVSGNIIFIGLIVPQIAK
                     GIVGSDYKYIIPSSLVLGAVLLVYTDILSRMINPPYETPVGSITALIGVPIFIYLVRK
                     GEK"
     gene            complement(44989..45927)
                     /locus_tag="KR231_000038"
     CDS             complement(44989..45927)
                     /locus_tag="KR231_000038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HBH0002458.1"
                     /translation="MKKIKSLAIFISIITTLVLVTACSDKNTEDKDKSETRVVQSVKG
                     EVKIPSNPKKIVDISGSSEELLLAGYKPVATANVDSYETDKLPSYIREELKGVKIVGH
                     SMMDTMDMEAILEVNPDLIIMSQRQEKIYDQLKEIAPVVMMKDYANDWRSKLTDVSKL
                     FDKEEEDKSWLQKYDEKATKLGKEVIEKNGEKTYLPVLASSGQFMVFSDGGIGTLIND
                     DMKLARPKNMPKQDGITLPMVSMEGLTDIDADHIVVIATEADKKDLENSAIWAQIRAV
                     KDGNVTILDAAPFFSQSYNPIGKELLLESVKNELTK"
     gene            46197..46661
                     /locus_tag="KR231_000039"
     CDS             46197..46661
                     /locus_tag="KR231_000039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016208838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0002459.1"
                     /translation="MVHLVYCDNAGKKGEKVLDKILDGTKTMVIRGAAGRKIPHSRVF
                     EDELLYFMEKGTAKISAKATVKKVENYVKLTEDEISKILNENQPKLNLSEKQKVRWHK
                     KCLCLVEFENVEEITPLDFDHQGNMDDWLIVEKIEDVVVGTSIPYNYEKSKF"
     gene            complement(46773..47090)
                     /locus_tag="KR231_000040"
     CDS             complement(46773..47090)
                     /locus_tag="KR231_000040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HBH0002460.1"
                     /translation="MDEKMIEISFGIIGFAGDAKGLAFEAIKEAKSGNIDKARECIEK
                     SKESIHKAHKFQTELIQNEANGNKTEISVILIHAQDHLMTAMNFQQLAEEFIDVYERL
                     ESK"
     gene            complement(47103..47834)
                     /gene="chbG"
                     /locus_tag="KR231_000041"
     CDS             complement(47103..47834)
                     /gene="chbG"
                     /locus_tag="KR231_000041"
                     /EC_number="3.5.1.105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chitin disaccharide deacetylase"
                     /protein_id="HBH0002461.1"
                     /translation="MTKIIINADDFGYCEAVNYGIISAHNNGIVRSTSMMANMPGVEH
                     GVGLLKENKTLNCGVHMTLSCGRPLLSNLKTIVDKDGFFIRRITDEIIEKMDCDEIYR
                     ELCAQIDRVKGLGIDISHLDSHHHIHTLVSLKPVIEKIVTKYNLPIRGGFEYNLEYSK
                     VVPLIDSFYKENVSEEYFIKNIDEIMKYDVVDIMSHPAFLDDYILNSTSYAIDRTKEH
                     KILTSKKVKEFLEKNGLVISSYRDI"
     gene            complement(47860..49170)
                     /locus_tag="KR231_000042"
     CDS             complement(47860..49170)
                     /locus_tag="KR231_000042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861728.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HBH0002462.1"
                     /translation="MKKGLKIVTIGGGSSYTPELVEGFINRYEELPVKELWLVDIEAG
                     KEKLEIVGNLAKRMVKKAGVDMKINLTLDRREALRDADFVTTQLRVGLLDARIKDETI
                     PLSHGVMGQETNGAGGLFKALRTIPVIFDIIKDVEELCPNAWMVNFTNPTGIITEAVF
                     KYTNFRRYIGLCNVPIHLKNDVAKLFNVESDRISMDFAGLNHMVYGLNVSLDGEDVTK
                     EAIDKFVKADISMQNIKAIDFNAEFVKSLGAIPCPYHRYYYKTKEMLEDELREFKEGK
                     ARGQVVKELEEQLFELYKDEKLDVKPPQLEKRGGAYYSDAACNLISSIYNDKKDIQVV
                     NTLNKGSIRDFKDEQAVEVSSVITKNGPKPISIGYLPDSVHGLVSQIKSFEVLAAKAA
                     VYGDYESALLALCINPLIPSDDLAKTILDEMLEAHKDYLPRFNR"
     gene            complement(49267..50580)
                     /locus_tag="KR231_000043"
     CDS             complement(49267..50580)
                     /locus_tag="KR231_000043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBH0002463.1"
                     /translation="MEKFMSFMDKYIVPVAAKIGAQRHLVAVRDAFIVMIPITMVGAL
                     GTLINNLPLEAYKNLMASIFGENWTTFGGDLWWGAIGTMAVFLVIGVAYFLAKSYESD
                     GLQSGLIALSIFFIMAPQIGKIVPEGGTTVVEGWGMIQQTYLGTAALFSSILIGLLST
                     EIFVRLSKVKKLTIKMPDGVPPAVSRSFAKLIPGMLTIMIFTVIGIFIKMLSNGSFLT
                     DILNTYLGAPLSNVADSLGSTMLIAFIIHILWTVGLHGANIALPFTETILMKLGGENA
                     ALAQAGATEGYHVLAGAFFDAFVYLGGSGMVLGLIVALLIAGRRRKEMIVLGGPPAIF
                     NIGEPLIFGLPIVLNPIFMIPFVLAPVICSAVSYLAIDFGLVAPVILPKIPWVTPPIL
                     GGAMATGDWTGGALALFNLILSILIYIPFVIASEKMEANKLKINN"
     gene            complement(50602..50913)
                     /locus_tag="KR231_000044"
     CDS             complement(50602..50913)
                     /locus_tag="KR231_000044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBH0002464.1"
                     /translation="MIKIMLACSAGMSTSLLVTKMEDAAKENGIEAKIWAISEVNLKN
                     EIENCDVLLLGPQVRYVLGKATEMAKPYNIPVEVINMMDYGRCNGKAVLDRAVELNSS
                     K"
     gene            complement(51113..51817)
                     /locus_tag="KR231_000045"
     CDS             complement(51113..51817)
                     /locus_tag="KR231_000045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBH0002465.1"
                     /translation="MKEPIYKVIENHVRELINSDSLKEGDLIPSEKQLSEEFNVTRMT
                     VRSALNNLVKEGYITRQRGVGSIVIANNIYDNISSVSGFTKEMESKGYKVSNILVSLE
                     IVQADENLSSKLNISLEENVWEIKRVRLANDARVSYMITYMPVKLFPNLNKTHCENSL
                     YNFVEEVCEYKIAMSEREVQAVISNEECMDNLKLEEPEPLLYISQICKLQNSEIFEYS
                     HTYHYGYTLTLNAVVE"
     gene            complement(51908..53269)
                     /locus_tag="KR231_000046"
     CDS             complement(51908..53269)
                     /locus_tag="KR231_000046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861729.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HBH0002466.1"
                     /translation="MKDRLNLTEGRITEKLLKLSLPIMGTSFIQMGYNMIDMIWVGKA
                     GSKAVAAVGTAGFFPWLAMAFIMISKVGGEIKVAQSIGANNISTTKSYMKSAIEINII
                     LAIIYTISLIVLNKQLIGFFRLGDLEVITMSRQYLIIVALGMVFYFINPVFTAIFNGL
                     GNSKTPFRINTVGLITNIILDPILIFGWGFAPKLGVAGAAIATVFAQIVVTTCFIYII
                     VKSKEEYFKLRLFKEIETKYYKVLYKLGLPIAIQSGMFTVFSMLLGVIVASWGPVAVA
                     VQKVGSQIEAISWMTAEGLSVALGSFVGQNYGAKKYSRINKGCKIAITVSSVLGIITT
                     LVLVFAGESIFSIFIDESEAIEKGAVYLKILGYSQFFMCLEIITTGAFKGLGRTYIPS
                     IIITILTGARVPLAYFISRPEMLGLNGVWWSITLSSILKGILMISLFISLLKLGKLYK
                     ISE"
     gene            53768..54922
                     /locus_tag="KR231_000047"
     CDS             53768..54922
                     /locus_tag="KR231_000047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GGDEF domain-containing protein"
                     /protein_id="HBH0002467.1"
                     /translation="MKINKKFNRVDMQVSILTAIIVIISSSCVYFFNYTLTYKSMIYS
                     LSERSKHIYEYVERNIDKNTFTEINSKEDQSKKSYKSSKILLESVKNTTGVMYLYTAK
                     KTKDGSLVYVVDGLNSSRSDFRNAGDLIEKEIWGDLNKALDNHILLPKKIKSTSWGYI
                     FISYFPIHNDVGKVVGVIGIEFEAKHQYNTFKFISIVTPIIALLTCLISALIAVILFK
                     RISNPTYTDFANTDYLTGLKNRNAFEIDMNNLNNSNLKNLISIISIDLDGLKKINDKF
                     GHQTGDLYIKQASKIIQYVINKKYIVYRIGGDEYIIILKNLSHKEINNIINNINLKIV
                     EENSTNELKLSMSIGYAIFDEKVDVSLFDTYRRADSQMYDNKRKINKQYQ"
     gene            complement(55004..56722)
                     /locus_tag="KR231_000048"
     CDS             complement(55004..56722)
                     /locus_tag="KR231_000048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative 2-aminoethylphosphonate ABC transporter
                     permease subunit"
                     /protein_id="HBH0002468.1"
                     /translation="MNNNAISSKSISLKSKMNLDIKKCMLTVLVMSLVIFLLAPIIYL
                     FVQAFLDKDGVFVGLQNFQEYLASESLLNSLKNTVFVSVISTVISLTLALVYAYALTR
                     TKIKFKGFFKSLAMFPMFAPTMMHAIGLVYLFGNQGLVTNLLGVHVPIYGAVGIILAQ
                     IIYVFPQSFQILYISLSSTDYRLYEASNTMGISKIREFISITIPSIKYSLISSAFVSF
                     TLCFTDFGAPKVIGGEFNVLSIDVYKQIIGQQNMPMGATVSILLLIPAIISFIVTKKI
                     EKNQNSYITSKSIPYKVKTNKLRDSILGGVVGIIAFGIIAVMLTVILSSLISVWPYDL
                     RLTLEHFSMKNSIDGIKPFINSIKMSLFTAILGTSFVFLFAYLNEKTEKAPYLKSFGY
                     FLSTLPMALPGLVLGIAYVLFFNKLEFNFMDTIYIKNLFNGLYGTLLIMVICNIVHFF
                     SVAFITATTAIKKVDKELDMVAKSMGINSASILKNVTIPLCLPAVLENFMYFFLNSMV
                     TISALVFIYTASSKVAAISIVQLDDKGSTAQAAALAVLILVTNILVKVIYEFIKNRLE
                     KRTNFN"
     gene            complement(56727..57716)
                     /locus_tag="KR231_000049"
     CDS             complement(56727..57716)
                     /locus_tag="KR231_000049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBH0002469.1"
                     /translation="MSYLKINNVFKSYDQKKVLNNISLDIEEGEFLCLLGPSGCGKTT
                     LLRIIAGLEDVNSGTIILQDKDITNLEPSKRGFGIVFQSYALFPNMTAYNNIAFPLKE
                     RKVSKEKIDNKVKEVLETVGLTNEAHKYPKALSGGQQQRIAIARALALEPKFLLLDEP
                     MSALDAKVRHKLRMDIKRLQKELNITTIMVTHDQEEAITMADKIAILNGGDIMQIGTP
                     EEIYQNPQNLFTAQFIGDTNCFDNGDSILTVRPEYVQIEKSTKENYQGIISNIEFRGN
                     LLRVEIKDKLNENFIISDVSIKEWVNLNLVEGDLVKISIDEKYYLKYPKVKGA"
     gene            complement(57812..58861)
                     /locus_tag="KR231_000050"
     CDS             complement(57812..58861)
                     /locus_tag="KR231_000050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative 2-aminoethylphosphonate ABC transporter
                     substrate-binding protein"
                     /protein_id="HBH0002470.1"
                     /translation="MKEFIFTCLCIVVITFMTSCISTTPQTTQGKGNNKLTIYAALEE
                     EQIAYYMEGFREEYPNIDVEIVMDSHGVIASKLLAEKDNPQADIIWGLSAMNMIELKK
                     DGALEAYKPKNYDKVDKKFKDTEDDVSWVGMSVPETAIVVNYKELKKLGIDIPKSYED
                     LIKPEYKGLITMPNPASSGTGYLTVSGLIQMMGEKDAYNYMDKLHKNIATYTHSGSKP
                     AKLAGSGEYPIGITLGYRATQQLSSGEPIEVVFPKEGSGWDLEANALVKKDNIKKEAK
                     LFLDWAISDSAMDRYAHEVAVTSIKTDNPVPKGYSKQPFEQLIKEVDLNSAAKNRSTV
                     LKTWESKYGSKSESK"
     gene            complement(59138..59806)
                     /locus_tag="KR231_000051"
     CDS             complement(59138..59806)
                     /locus_tag="KR231_000051"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit D"
                     /protein_id="HBH0002471.1"
                     /translation="MARLNINPTRMEMTRLKKLLKTATRGHKLLKDKLDELMKQFLEI
                     VRENKRLREEAENALDTAYKNFIIARAVMSQEYLGSALMMPKQSVSVDVSTRNIMSVD
                     VPVFDFKTENNQSDIYPYGLAFTSGELDSAMEAFSDAMQPLLRLAESEKSAQLLAQEI
                     EKTRRRVNALENVMIPNYIETIKYIAMKLEENERASTTRLMKVKDMVLKKALEEKKKN
                     DLVV"
     gene            complement(59812..61185)
                     /locus_tag="KR231_000052"
     CDS             complement(59812..61185)
                     /locus_tag="KR231_000052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit B"
                     /protein_id="HBH0002472.1"
                     /translation="MIKEYKSIQEVAGPLMLINGVEGVKFDELGEIELSNGEIRRCKV
                     LEVNGDTALVQLFESSTGINLAESKVRFLGKSLDFGVSPDILGRVFSGMGRPIDGGPE
                     IIPDKRLDINGAPINPAARDYPAEFIQTGVSAIDGLNTLVRGQKLPIFSGSGLPHANL
                     AVQIARQAKVRGTDSKFAVVFAAVGITFEDAEFFISDFKATGAIDRSVVFVNLANDPA
                     VERVSTPRMALTAAEYLAFEQDMHVLVIITDITNYAEALREVSAAKKEVPGRRGYPGY
                     LYTDLATMYERAGKMKGHEGSITMIPILTMPEDDKTHPIPDLTGYITEGQIILSRELY
                     KKDIQPPIDVLPSLSRLKDKGIGKGKTREDHADTMNQLFAAYSRGKDAKELMAILGES
                     ALSEIDLMYAKFADEFEKEYVSQGFRTDRTIEQTLEIGWKLLSMLPKSELKRIRDEYF
                     EKYMPKE"
     gene            complement(61182..62960)
                     /locus_tag="KR231_000053"
     CDS             complement(61182..62960)
                     /locus_tag="KR231_000053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit A"
                     /protein_id="HBH0002473.1"
                     /translation="MKTGTIVKVSGPLVVAEGMRDANMFDVVRVSDKHLIGEIIEMHG
                     DKASIQVYEETSGLGPGEEVVSLGMPMSVELGPGLISTIYDGIQRPLEKMYDISGTNI
                     TKGVEVSSLDRTTKWEFKPKKSVGDKVVAGDIIGGVQETAVVECKIMVPYGVKGTIKE
                     IYSGEFTVEDTVCVITDEKGNDIPVTMMQKWPVRKERPYREKKTPDSLLVTGQRVIDT
                     FFPITKGGVAAIPGPFGSGKTVTQHQLAKWADADIVVYIGCGERGNEMTDVLLEFPEL
                     KDPRTGESLMQRTVLIANTSDMPVAAREASIYTGITIAEYFRDMGYSVALMADSTSRW
                     AEALREMSGRLEEMPGEEGYPAYLGSRLAQFYERAGKVNCLGMDEREGTLTAIGAVSP
                     PGGDTSEPVSQATLRIVKVFWGLDASLAYKRHFPAINWLTSYSLYQEKVDVWADKNVN
                     DNFSAQRAQAMKLLQVESELQEIVQLVGVDSLSDGDRLILEVTRSIREDFLHQNSFHE
                     VDTYTSLHKQYRMMGLILKFYKSAQDAIKQNVTINDIIKLSVLEKIGRAKYVEEGDID
                     AAYDSIEDEIDNELADLIKKRGAEEL"
     gene            complement(63077..63400)
                     /locus_tag="KR231_000054"
     CDS             complement(63077..63400)
                     /locus_tag="KR231_000054"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit F"
                     /protein_id="HBH0002474.1"
                     /translation="MLMYKVGVVGDKDSIMGFLALGIDIFPAYDSDEIKKSIHKLVED
                     EYAIIYITEQASLLAKESIAKYKDYQLPAIIVIPGIGGSMGLGMNEVRESSKRAIGAD
                     ILFKE"
     gene            complement(63387..64364)
                     /locus_tag="KR231_000055"
     CDS             complement(63387..64364)
                     /locus_tag="KR231_000055"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit C"
                     /protein_id="HBH0002475.1"
                     /translation="MAEEKTYPYAVARIRVLEKQLLNRQMFIQMAEAKSPEDSLRIIA
                     EAGYADTSNNNIHNFENILTQELSKTYEILKSLAPEEKFVDVFLYKNDYHNLKVLIKE
                     EISGVDGEKYLIDGGTIPLIKLRESLANRSFSDLPKIMSSAILEAFDVYNKTQNGQMV
                     DIVLDKATFTSMKETAKESQNKFVIDYVMKVCDLTNLKSFIRVKNMKKDFDMFMNVFV
                     SGGSLDKEKFLEAFSSDTPASCFKSTSYSDVCKNGMDSGFTVFEKLCDDYLMEYVRGA
                     KFKPLTLEPLIAYLYAKESEIKTIRIILTSKLNNIDADTIKERLRDAYV"
     gene            complement(64379..64942)
                     /locus_tag="KR231_000056"
     CDS             complement(64379..64942)
                     /locus_tag="KR231_000056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit E"
                     /protein_id="HBH0002476.1"
                     /translation="MGNEQKMIDRIIADAKQEAQEILDKAKSEADLKVNSANEKAEKE
                     MASYTKLAEAEAEKAASKEISGAYMEAKKQILSKKQEILEEVILEAKNKLLNLKDNEY
                     EEIILNMIEKSNCTDDSEIVLSKKDKKTLKDVLSKKGIKVSDETRDITGGFIVKKGDI
                     EYNYSFEAIIAVEHEYIEQIAAEILFN"
     gene            complement(64994..65485)
                     /locus_tag="KR231_000057"
     CDS             complement(64994..65485)
                     /locus_tag="KR231_000057"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit K"
                     /protein_id="HBH0002477.1"
                     /translation="MEFLNALGNGQFLAISGAAIAALFAGMGSAKGTSIAGQAAAGVV
                     TEDPSKFGQLLVLQLLPGTQGLYGFIIAFLILSKAGIIGGDAIPTSAQGLQLLMAGLP
                     IGLVGLVSGIAQGKAAAAGVGIVAKRPEELGKAITFAAIVETYALLGLLVSFLAYNGI
                     AIG"
     gene            complement(65488..67413)
                     /locus_tag="KR231_000058"
     CDS             complement(65488..67413)
                     /locus_tag="KR231_000058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit I"
                     /protein_id="HBH0002478.1"
                     /translation="MAIVNMNKISIVGLEAQKSQILKLLMNRGFVQIDDSAFLTEEEE
                     LKNYLVKDSEESEVIMLEQKMSHVNQAINIVSSLVKQKKSLLAPKREFNKIDSEKEGQ
                     VYAEALELNNLHKEIGTIRSNINLLNNNKSMLEPWVNFDIPIENMETKYTKTILGTVP
                     ISANIDALRVKLEDEIPESVIGIVNSDKLMNYVYLITLKETFDDVLEVLKEFNFSVVS
                     LPNEEGTPLQAIKKYNEMIIRQENVSKDKTEEIKRHADSIHMLENLYDFYTIERDQKK
                     IIERLVKTKTTFCLNGWLPSKRADELIKEITEKFDCCVQTEEGSKEEGFPILLENNKL
                     VTPFESVTNMYSYPSTKDIDPNTILTFFFVIFFGMMLSDAAYGLIIAVVCGFVVYKLK
                     IQKGEGNLIKLIGICGVSTTVWGLIFGGILGDLIPIKALINPLEDVMTLMGMSLLFGI
                     IHIYVGLGIKAYTLIRSGKVIDAIFDIGFWYLCITGVCLLIIPFVAGDIGVFSEVGKY
                     LAIIGAIGLVLTQGRSFKGIPVKLFKGFSSLYGITSYFADILSYTRIMALCLTTGVIA
                     QVINLLGAIAGPILAVVIGVVGHTINLLINALGAYVHTSRLQYVEFFNKFYEGGGVPF
                     VPFKYKTKYTSINKKEM"
     gene            complement(67415..67726)
                     /locus_tag="KR231_000059"
     CDS             complement(67415..67726)
                     /locus_tag="KR231_000059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0002479.1"
                     /translation="MAFEIIKSIVEAEQTADSIKVKAVTDAESIRADAVNKCESIFAD
                     VKKQAKLMEETLIEKAVTDSRAEVDKILANAKSECLKIEKTAEERKSKAIEAVIGKVV
                     R"
     gene            complement(68356..68631)
                     /locus_tag="KR231_000060"
     CDS             complement(68356..68631)
                     /locus_tag="KR231_000060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Nif11-like leader peptide family natural product
                     precursor"
                     /protein_id="HBH0002480.1"
                     /translation="MNEKLTKILEEAKNDDEFRKELIKTREQRDVMDSFCKVVTSRGY
                     DMTVGELFSMGEEYTSNLLKSVNGGAAYPIEDWSDWYEDFFIMLSNI"
     gene            complement(68746..70155)
                     /locus_tag="KR231_000061"
     CDS             complement(68746..70155)
                     /locus_tag="KR231_000061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906176.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L,D-transpeptidase/peptidoglycan binding
                     protein"
                     /protein_id="HBH0002481.1"
                     /translation="MIDGKEVKQESGQKNLKFKIAIVVGVLFVAYIGMAIFFRNHFYF
                     GTTINGVKASGKTVEQVNDLLASSTNSYTLNLEERNNKKEQIKAKDIDLKFTPDDKVQ
                     KIKDSQSAIGWIGGIFKSKEYNNMITLSYNKDLLEKRFNALSCFDSKNVVEPKSAYPK
                     YDSTKNAYVIVPEVLGNKVKKDDFYKLVQNSINSGNTSISLDESKVYEAPNNTKDSEK
                     LKQAIKTLDKYVGVVVTYDFSDRKETLDGSEINKWLKVDSEKNYDITFDNDAMVEYTR
                     GLSKKYSTFGDSRPFKTATGKDITISGGIYGWLIDKKKEAEALVDVVKAGKNVTREPI
                     YIQKAVSRNKDDIGNTYVEISLSGQHMWFFKNGEMLVSTDVVTGDLARGFATPSGIYP
                     LNYKARNVSLTGQGYSSPVSYWLPFNGNIGIHDATWRNSFGGSIYKSSGSHGCVNTPF
                     SKAKKIYENIEPGTPIILY"
     gene            complement(70527..71189)
                     /locus_tag="KR231_000062"
     CDS             complement(70527..71189)
                     /locus_tag="KR231_000062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA-binding protein"
                     /protein_id="HBH0002482.1"
                     /translation="MIDISIDDKLKERWPNAKLGCIQAKVAVNKSSEKLINEINEFCD
                     TINQSLKVEDITKLDKIKDARNAYKELGKNPSRYRTSSEALVRRIIQGKGLYTINNIV
                     EINNLISIKSLYPVGTYNVSKLHSPVCFTVGDEGEQYKGIGKELINIENLPILSDSVG
                     KFGSPTSDSERAMITEDANEILICIFSFSQESDIEEYFGYAKELLKEYADGKDIETKI
                     IK"
     gene            complement(71443..73662)
                     /locus_tag="KR231_000063"
     CDS             complement(71443..73662)
                     /locus_tag="KR231_000063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EAL domain-containing protein"
                     /protein_id="HBH0002483.1"
                     /translation="MTGRNKSFTLITILFLTSLFLTMGYIYIEDTKHLLMSEAKIHIK
                     EVAVQGSQLAQRQIEKDLDVLNIFSNYYASNPDIPNEEKMKNLLDEMENQKFYTMAIV
                     DINGNAENTKGDKFSVKDREFFKNSIKGKKYVSSPYVDEVNKSIKKIAISVPLLNNDK
                     VVGVLYCTYNINTLMKLINISFYENNSISYVVKNDGTIILHPQGDSLSKNIYKLLEQD
                     NDIQEVNRLKKELQENKTGATVLNMLEERRYLGYATMDNGNSENNYIKDWNLIFSIPE
                     TVVFSNSKQIINRAVYAVLSIVLIFVAIIFYIIYIKKSNEKEILSLAYEDKVTYIGNQ
                     NKFYRECSKYLLDKPSLNYIIVYFDINNFKMINDTFGYEFGDNLLITIAKALKEELTE
                     GEVYARLSSDYFAIFCDYKNGRNKIIRKLDNIRSNIESNLSIVFEISLCVGIYFVEEG
                     EVDIQKAVNKANMARSVAKGKNINYAIYNEDVRNKLSEESMILDDIKIALVKNQFEVY
                     YQPKFSLVTGEMIGSEALIRWNHPEHGFISPAVFIPIAEKSKLILKIGRFVFERVCND
                     LYEWKKQGKKIVPVSVNLSRVELYQPDIVKFINKTIKMYNLSSDFIEIEITETVAINE
                     LNILKNVLNELRTYGFSISMDDFGTGYSSISCLRDMPIDILKLDKSFLGGIEHDERSR
                     NIAKSIVSLAKSLDLVVIIEGVESKEQAELMKQFGCDLVQGFYFARPMPAKNFLDLL"
     gene            complement(73938..76592)
                     /gene="adhE"
                     /locus_tag="KR231_000064"
                     /gene_synonym="adhC"
     CDS             complement(73938..76592)
                     /gene="adhE"
                     /locus_tag="KR231_000064"
                     /gene_synonym="adhC"
                     /EC_number="1.1.1.1"
                     /EC_number="1.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional acetaldehyde-CoA/alcohol
                     dehydrogenase"
                     /protein_id="HBH0002484.1"
                     /translation="MAHKEQVIIENKKENEVMSVGLDTVNNVESLVKKLAKIREAQKI
                     FATYSQEQVDKIFLAASLAANKQRVPLAIMAQKETGMGIAEDKVIKNHYASEYIYNAY
                     KETKTCGVIEKDEAFGMTKIAEPIGVIAAVVPTTNPTSTAIFKALLALKTRNGIIFSP
                     HPRAKNSTIEAAKVVLEAAVLAGAPEGIIGWIDEPSLELTTTVMKEVDLTLATGGPGM
                     VKSAYSSGKPAIGVGAGNTPAIIDDSADIKTAVNSILVSKTFDNGMICASEQSVIVLE
                     NIYNEVKKEFKERGAYLLDKDETEKIRNIILVNGGLNSKIVGQTACTIAKLAGFEVPV
                     DTKVLIGEVESVEIEEAFAHEKLSPVLAMYKASDFDDAVRKAEKLVEDGGFGHTSSLY
                     IDDVNQREKLDKFTSAMKTCRILINTPSSQGGIGDLYNFKLAPSLTLGCGSWGGNSVS
                     ENVGVKHLLNIKTVAERRENMLWFRAPEKVYFKKGCLGVALKELKDVMNKKRAFIVTD
                     TFLYNNGYTKAVTDLLDEMNIKYTTFFEVEPDPTLECAKIGAKAMREFNPDVIISIGG
                     GSAMDAGKIMWTLYEHPDVDFQDLAMRFMDIRKRVYTFPKMGEKANFVAIPTSAGTGS
                     EVTPFAVITDQDTGVKYPLADYELMPNMAIVDSDMMMNMPKSLTSASGIDALTHALEA
                     YVSMLATDYTNGLALQAIKSIFEYLPRAYDNGAKDPEAREKMANASTMAGMAFANAFL
                     GVCHSMAHKLGAFHHVPHGVANALLITEVMKFNSSDAPKKMGAFSQYKYPEALKRYAE
                     IASFLGLKGNSDEEKFQSLLVAIEDLKLKVGIPKSIKEFGVEESKFMDSIDEMVIQAF
                     DDQCTGANPRYPLMNEIKDMYLNSYYGR"
     gene            77096..77296
                     /locus_tag="KR231_000065"
     CDS             77096..77296
                     /locus_tag="KR231_000065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0002485.1"
                     /translation="MEKLKTISVFSLIISVILTIGGIGIVTYYVDNLFIRGLSVFVLI
                     MSSSFVSTTVRLIFEESKRYKF"
     gene            complement(77503..78093)
                     /locus_tag="KR231_000066"
     CDS             complement(77503..78093)
                     /locus_tag="KR231_000066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipicolinate synthase subunit B"
                     /protein_id="HBH0002486.1"
                     /translation="MRLEGLTIGVGFTGSFCTYDKIFIELENLVKEGANVHTIFSDVS
                     QNIDCRFGNSEEFMKKAYELTGNKPIVTIEEAEPFGPKGIADIIIIAPCTGNTAAKLA
                     NGITDSPVLMAAKGHLRNDKPLVISISTNDALSFNFKNIGILLNSKNIYFVPFGQDNC
                     KAKPNSMIAHTELIIPTIELALENKQLQPVIKSPHQ"
     gene            complement(78096..78971)
                     /gene="dpsA"
                     /locus_tag="KR231_000067"
     CDS             complement(78096..78971)
                     /gene="dpsA"
                     /locus_tag="KR231_000067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipicolinate synthase subunit DpsA"
                     /protein_id="HBH0002487.1"
                     /translation="MSNQYDITVIGGDLRQVYMVKKLINKGYSVVTYGISNEIINGIV
                     GKSTSLAEALSKSSIILCPIPFTKNQVNIENTDDCLDATIDNLLINLSPNQILFGGNI
                     PTKVCKFCEQHSIQIYDFMKMNDVAILNAVATAEGAIAEAIKRSIINIHQSNCLVLGY
                     GRCAQILAKKLYALDANVCVGARNNDARSTANAFGYSSISLSQLDEKLLQFDYIFNTI
                     PECILTKERLEKVSQEVTIIDIASSPGGVDYSVVKEAGINATLCLGLPGKYSPKTSGE
                     ILVNAIENIINERRD"
     gene            complement(79047..80438)
                     /locus_tag="KR231_000068"
     CDS             complement(79047..80438)
                     /locus_tag="KR231_000068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422637.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AMP-binding protein"
                     /protein_id="HBH0002488.1"
                     /translation="MNYYELLRIKKERHKNKNFLIIDGEKYTYENILSYSEELGKQIS
                     LGENIPILIYSKNIMFQLISFFAINYSKNIPIICHYNLSKKVLDDILLKNNISIIISD
                     ESMDVIDLYDDNNNEVAKKVNFSIFNPKFNIYMYQYKNLINYLDKSICMGALSSGSTS
                     VPKVLYRTYESWAGFFPIQNGIFNISGESILFVNGTLSFTGNLNSIMSVLYEGGSIVI
                     SSGLNCKSWIRIIKQYNVTNIYLIPTKLQLLVKHLKEPVLKVVSIFTGSQLLFEDTAR
                     NLKKYMPKSEIILYYGASELNYITYLCYDELIEKPLSVGRPFPGIDIYIREGKIFVNT
                     EYAVYNATKPYSVNDIGYYDNDGYLIFEGRSDDILNIGGFKVSSTKIENEVKKIPQIE
                     DAIVLPYSDTIRGNQIVLFVITIDKITKKDLLIKMKDNLMKNEIPKKIIFLNSFPYTS
                     SEKIDRLALLKML"
     gene            complement(80442..81578)
                     /locus_tag="KR231_000069"
     CDS             complement(80442..81578)
                     /locus_tag="KR231_000069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891252.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiolase family protein"
                     /protein_id="HBH0002489.1"
                     /translation="MKEVFILGGLRSHIGLKNGIFQFVQPELLGASVLKDLIKKYEID
                     KIDEIICGNAVGTGGNIARLMTLTAGVSNEVPAFTVDMQCASAMMSIDIAFSKVKSGQ
                     CDLIIAGGFESSSLQPMRTYHKNDKRYNTNNPNYTVAQFSPDDNSQNSMLEGAERVAE
                     LYQIEKADLDFWVKESHKRAKEAREEKILEDIISPINNSTYDEGIRDKMSQRLLDRMP
                     SILGKETITNAANSCLINDGASFIIICSKKYLEHVKKKPKAKIINTCTIGTDATLSPT
                     SAIQAMDKLLEIESLNYLDVSAVEFNEAFAVIDVLFQRKYPELIDRYNIFGGALAYGH
                     PYGASGAIIALHLLKALEKTKGRYGICSIAAAGGLGSALLLERV"
     gene            complement(81610..82155)
                     /locus_tag="KR231_000070"
     CDS             complement(81610..82155)
                     /locus_tag="KR231_000070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin transporter BioY"
                     /protein_id="HBH0002490.1"
                     /translation="MKNTKVNIQDLTKMSICVALLCISSYIYIPLPFTPAGVTAQTIM
                     INLIALILTPRQAFSTVGVYIMIGLIGIPVFGGGTSGIGKLLSPTGGFYFGFLFAALI
                     ISLLKGRNNDIKRYILITIFVGMPIIYFMGTVFMCYFNQMTVEAALFAAVVPFLIGDT
                     IKSVIASFLGTKLNNVLRRNL"
     gene            82479..83258
                     /locus_tag="KR231_000071"
     CDS             82479..83258
                     /locus_tag="KR231_000071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0002491.1"
                     /translation="MKVNENNINNIDEELDELSRKVYLESPDFWISISDKIIDKVFDE
                     MLLFFAVKYNYFNIVCFAIENNYLDLNMPSKNKKYTNIMEHLLDTSKQNEDKKIYNYL
                     LSLNKGNNLDERPILDELNCNISSDTFEKKDIYLPKYLCPSCNSNIFDTGYKVSNDIT
                     YKFSSKEAEPIEMCSEVSSIRCCNCDELLEDITLDKLYNLCKIQNCNNCGSNLTKVGI
                     IAKKKMNFDENTEKFKDVSTSYCCGNCDSEINLSQREHFKI"
     gene            complement(83713..84141)
                     /locus_tag="KR231_000072"
     CDS             complement(83713..84141)
                     /locus_tag="KR231_000072"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyltransferase"
                     /protein_id="HBH0002492.1"
                     /translation="MIKKLNNKDINKIMEIWEKSTIKAHDFISKEYWQNNYNTVKNEY
                     IPISDTFVYDDGDEIKGFISIIDKSFIGALFIKPKYQNLGIGGKLLDYATKKYKSLSL
                     AVYKDNKKAVVFYNKKGFNIVKEQVNEDSGFKEYIMEYSK"
     repeat_region   84202..85995
                     /inference="COORDINATES: alignment:crt:1.2"
                     /inference="COORDINATES: alignment:pilercr:v1.02"
                     /rpt_family="CRISPR"
                     /rpt_type=direct
                     /rpt_unit_range=84397..84425
                     /rpt_unit_seq="atttacataccacttagttaatataaaac"
     gene            complement(86179..86445)
                     /gene="cas2"
                     /locus_tag="KR231_000073"
     CDS             complement(86179..86445)
                     /gene="cas2"
                     /locus_tag="KR231_000073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CRISPR-associated endonuclease Cas2"
                     /protein_id="HBH0002493.1"
                     /translation="MFVIVTYDIVEARSLNRIRRILRKYLTWTQNSVFEGNITEGKLH
                     KCISEIENIIDNSEDSIYVYEIKNPNSIKKKCYGIDKYSDEMFI"
     gene            complement(86448..87428)
                     /gene="cas1b"
                     /locus_tag="KR231_000074"
     CDS             complement(86448..87428)
                     /gene="cas1b"
                     /locus_tag="KR231_000074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I-B CRISPR-associated endonuclease Cas1"
                     /protein_id="HBH0002494.1"
                     /translation="MYKDYYIISNGDIKRKENTIYYYNLEGEKKILPVEQVDDIHIYG
                     EVDLNTKLINYISKYGVMLHFYNYYGYYSGTYYPRKKNVSGFSLVCQSACYLDKNERL
                     YLAKSFVESASYHILRNMRYYKVDESLIDTIKDELNDLNDVKEISELMGKEGRIRKTY
                     YKSFNQILKDDFEFYKREKRPPKDPVNALMSFGNSIMYTNVLSEIYKTQLDPTISFLH
                     EPSTKRFSLSLDIAEIFKPIIIDTIIFSLINNKRINKNDFEYQDKICYLSEKGKKKFL
                     QEFENKMQTTIKHRNLNRKVSYRMFIRLECYKLIKHFINDERYKVLKVWW"
     gene            complement(87431..87982)
                     /gene="cas4"
                     /locus_tag="KR231_000075"
     CDS             complement(87431..87982)
                     /gene="cas4"
                     /locus_tag="KR231_000075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CRISPR-associated protein Cas4"
                     /protein_id="HBH0002495.1"
                     /translation="MWLKFTKEGDFVPIDLEVLKVQGVKINYYYVCKRKLWLFSKGIT
                     MEQNSSRVLSGKIVHEDSYKRMKNKEILIDDILKLDIIKDEYVKEVKISSKMKEADEM
                     QLYYYLYYLKNSMGIEKKGTINYVKEKKQEELILTEEKERIIENTLININEINMQLSP
                     PKIEKKHYCTKCAYYEFCFVKEE"
     gene            complement(87997..90318)
                     /locus_tag="KR231_000076"
     CDS             complement(87997..90318)
                     /locus_tag="KR231_000076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CRISPR-associated helicase/endonuclease Cas3"
                     /protein_id="HBH0002496.1"
                     /translation="MLYAKSNPVETLREHTDELLKQMNVLRESYGKNINSLDFLEEEI
                     FWQLLDFVIEFHDIGKAFSPFQELIKSRMDTKINEPKIVTYLENNVGHNYLSPAFIDY
                     SYIDRKKNKELRAVLNQVIVYHHERDIFIDKDFKNLIQKILDEDLINKVYELQHEFKV
                     RYPIKTEKLSKVYLQSVEKRIDKNHKYYNLYIMLKGILHRLDHSASAHEVVECNNVIN
                     IGEQTENYLMKEFGSLREAQSFAKSNRNKNIILIASTGMGKTETALIWIDKDKAFFTL
                     PLRVSINALFDRAKNIVGVGESNDTFLGLLHSTAIDYLEESNQENSSEIVDLAKLLSC
                     KLTFSTIDQIFKFPFLYRGYEKVYSTLAYSKVVIDEIQAYSPEIAAVLVKGIEMIHKI
                     GGRFMIMTATMPTIYIDELKKRGVMNSNLAELTCNTEKIRHCVSIVENSIDENLGKII
                     QSGMNKKVLVIVNTVKSAVEKYELIEEIVKPKGIDVNLNLLHSMYIQEDRAKLEKYIK
                     EFANSDRNGIWITTQLVEASLDIDFDELHTENSTLDSLFQRFGRCYRSREYEENSPNI
                     FIYTEKATGIGSIYDKDIVEKGLELLKTFINGKECVKMKEKYKVEMVKILYSKESLEG
                     TAFEKRFTSALNILDTITPYSLGSKDAQNILRNIEGYTVIPEDIYNKIEETLIKDYEE
                     LGQELINAYSNDDRQLINKIKSKRKKARREIIKKTVNLPIYKAKQNVIDIQVKGLEDL
                     KILLYKYDIYENKHTKQIFGKGVLISNEIDQFI"
     gene            complement(90329..91030)
                     /gene="cas5b"
                     /locus_tag="KR231_000077"
     CDS             complement(90329..91030)
                     /gene="cas5b"
                     /locus_tag="KR231_000077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I-B CRISPR-associated protein Cas5"
                     /protein_id="HBH0002497.1"
                     /translation="MKVLKLDLFQETACYKKPFAMKITETYPLPPYSTINGLIHKILN
                     ATEYIPFNISVQGTYESIFNNYQTTYFYKKDSITSMPMNSHMLLNVNLIIHIGGDFDL
                     LEEIYDSLLNYDEHLSLGRKEDLVRINDIRFVEVNKFEVDEDIQLDDYENYKLSECNI
                     RMPIYIPKTSLQDTDIDGISYRLNNYYDNNAVEDKKRVWNKVDSYYVEDGNTISIGDI
                     LLDNEGDLLYFNNIN"
     gene            complement(91032..91946)
                     /gene="cas7i"
                     /locus_tag="KR231_000078"
     CDS             complement(91032..91946)
                     /gene="cas7i"
                     /locus_tag="KR231_000078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861770.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I-B CRISPR-associated protein
                     Cas7/Cst2/DevR"
                     /protein_id="HBH0002498.1"
                     /translation="MKRGLTFTVIAQAQSLNYGEGIGNISELKKLSRDDGNIYTFASR
                     QCLRYDIVRLAAELFNWNLQVVDKEKGTIQFKDNISIRESEEMDLFGYMKTNKKDEKD
                     KKGGSLTREATVRLSNAISLEPYRSDMDFLNNKGLADRIGEHPNLANIEQHLSYYTYT
                     VTIDLSKIGKDGDIELDNKEKCRRVVEFLEIIKVLNRNIRGRQENLSPLFVVGGVYEI
                     ANPFFLGRIKLKGDKNGFKINKQAIEEVIQGTFLGKDLKEFTYVGMVDGVFINKEEFK
                     GLFEDNFLSVDKFFGQLVKEVKEYYGVN"
     gene            complement(91948..93798)
                     /gene="cas8a1"
                     /locus_tag="KR231_000079"
     CDS             complement(91948..93798)
                     /gene="cas8a1"
                     /locus_tag="KR231_000079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I-B CRISPR-associated protein Cas8b1/Cst1"
                     /protein_id="HBH0002499.1"
                     /translation="MKLRVYRGDWFFNMGIVGFLNIIKKADKQAEIFIMEDYIEFDSL
                     FLENFHEYYFNYFMDEYDVSKRIKKNIDYSINFIKSKPDRIKDGIKKIKDSVKQQNDK
                     IKKFDEEKFNMIKEKLDSMSKIKSYDEFDSLEALVDETIDIFKIKSINDRLTANLYKY
                     VVQDNYFGQVSFFNVAKAKLDLDGLKQVMFNDYLRQIIYFGELEDLLEENDYDKLKNY
                     LNDRLNSIAKDINEKKVSKSSINTIEKIMKEINKNFIKKNKSIEDIKKYMDSLEVCEM
                     CGLYKGILDEYSESNFAPLGVSTNNARNMFWNQAYVPSICDICKLILFCTPAGATYTR
                     KNYLINEENEFYLFVNMDTCINELFERNNSLKAQKSEYSDSKDENPFNQLIKSIVEEN
                     TLKSEWQLRNILFVEFKASIDSKKCKINYFNIPTYLAKFFVKENKKIQSIYDYKLKSN
                     VLDLILKSKDLKHLINNTLRNIVKSNLESNNKSNISGLSCFNVVQLRTILNNYKRGVY
                     KMDYKKLRKIYESGCEIHDYYIDKNAKNKIEGITYKILNLIKVGNKNDFMQTILRIFS
                     PSEKTPPEEILQIFVEEDLDFESVGYAFVTGLISGKYEGKDKLPNEKEEK"
     gene            complement(93804..94541)
                     /gene="cas6"
                     /locus_tag="KR231_000080"
     CDS             complement(93804..94541)
                     /gene="cas6"
                     /locus_tag="KR231_000080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CRISPR-associated endoribonuclease Cas6"
                     /protein_id="HBH0002500.1"
                     /translation="MKMKIEFSTGCIPISYNSLFMSIIKEAIRKSNEDYYKNMYYYKE
                     KNNKKTKNFTFSVYIKKYSIEGDNFIIEDKVILNISTPDLELGFHIYNGLMTSKKCLY
                     KDYELTRIRIDLSREKKVTEERVLFNALSPICVKSKEGKFLEITDDRYIEELNYITNE
                     VVKNYRGNGLKRKLEFENIGLKKVVVKESLREFKKITGKEYQYINGYKGKFILKGDID
                     DLNLIYNLGIGFRRAQGFGDVDILEWR"
     gene            complement(94619..95536)
                     /locus_tag="KR231_000081"
     CDS             complement(94619..95536)
                     /locus_tag="KR231_000081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WYL domain-containing protein"
                     /protein_id="HBH0002501.1"
                     /translation="MMILIQSRGKMKCKELSEELEVSERQIKSYKMYLEQAGIFINST
                     PGIYGGYEIDKCNSISLIKLLDSEVSILDMINSQLEYNNDIYKNEFNNIVEKIKAVLN
                     TGEKSDTYMDYFTVQAQRNCDYESEKNKCNEIIRAYTTKHKFWIEYYSLNSGNSERIV
                     HPYGLFNYKSDTYMVAFCEKRFKFIDFKLCRIKDYKVLEEKYNVDKSFSWDEYSKNSI
                     GIYKGEEINVVIKISHPFSTIIKEKVWVNNQQIIEYDDKSIMFKAKMRGYEEIKSWIL
                     SMGAYVEVVEPDRLRNDILLEIEKMKKIY"
     gene            complement(95815..97731)
                     /locus_tag="KR231_000082"
     CDS             complement(95815..97731)
                     /locus_tag="KR231_000082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBH0002502.1"
                     /translation="MNIKQFAINNISRNIKAYLGYLASIVISSSLLFSFIMFTSHPDL
                     DVSQFPDYLKEGLKMSKIIAYLFLFFFVFYSVSVFLKSRYKEFGILYITGISKRQVMK
                     LIFIENMIINIVSSVIGIIIGLIFAKIFLVVMSTFLELSPLKFYIPFNAILSTLIYFM
                     ILAVLTSIFTSFIVKENQVLKLLKGTKTPKPEPKTSLMLAILSICLFIIAYYNAITST
                     DQYTTYLRLVPVTSLTIVATYLFFSQFSVFFMKKLKLNKRFYRKNTNMLWISNLIYKV
                     KDNARIFFLITITSAVAFTAIGTVYSFWKDVERQINLIYPNTIYYSTMTLHNDPKKPD
                     SKEKDKERMMFIENNLKKENVDYTRINGEFKTVFPKKSDFNVRIMKESKYLEITETIG
                     VKPISFEDNECISLLSSSLPGNKNVKENIIVGNRGLKVAKQVEECVMPAYYKNMYVVK
                     DNFYDSIESKFIVDRFTAFEVEDSSKTIEICREFENKFNNESGMQPYLFFSKELMIGT
                     GKLMYSTFIFLAIFIGLIFFVTTSSFLYNKFYMDCQVDKKKYEQLNKLGMTYNEIKKA
                     STIEIGIVFLFPYVVAVIHSIFALTALKNSFDIEVASSAVLVMGSLFLVQIVYFLIVR
                     NNYLKEIRLNLVNF"
     gene            complement(97731..98477)
                     /locus_tag="KR231_000083"
     CDS             complement(97731..98477)
                     /locus_tag="KR231_000083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001637630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH0002503.1"
                     /translation="MKILTVNNLSKVYGKKIIFNALNDINFSIEDGEFVGIMGPSGSG
                     KTTLLNMISTIDKPTTGTMELKGKNPLLLRGEELALFRRRELGFVFQDFNLLDTLTIG
                     ENIVLPLTLDKVSVKEQDERLNEVSTILGIKDLLGKRTFEVSGGQAQRTAIARALINN
                     PSILLADEPTGNLDSKSSKVVMELFQKINKENKVTTMMVTHDPLAASYCSRILFIKDG
                     SIYNEIYKGSSREQFYQEIMDVLTLLGGDN"
     gene            complement(98581..99432)
                     /locus_tag="KR231_000084"
     CDS             complement(98581..99432)
                     /locus_tag="KR231_000084"
                     /EC_number="3.6.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl-diphosphate phosphatase"
                     /protein_id="HBH0002504.1"
                     /translation="MSLDVIFILKSVIIAIVEGLTEFIPVSSTGHMILVGNLIDFKGQ
                     FAEMFEVVIQLGAILAVVVLYWKKIKDSVIEFFKFIFTGGKEGKIGFRFGMNVIIGCI
                     PFAIIGVLFYDNIKSLFNLQSVIIGFIVGGILLLVVETLFRKKNHSTDNIDKITPIQA
                     LKVGTLQVLSAWPGMSRSASTIMGGWIAGLNSPTAAEFSFFLAVPAMVASSGKDLFEF
                     DYSIMTPTLWIALVVGFIVAFIVSIIVMEKFVNFLKKKPMRVFAVYRIIMGVVLAVLA
                     FTNIISV"
     gene            complement(99680..100684)
                     /locus_tag="KR231_000085"
     CDS             complement(99680..100684)
                     /locus_tag="KR231_000085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBH0002505.1"
                     /translation="MKLFLKDYKGYIFIYYIGIVMTIIYCNLMKFISFGESLYILLFS
                     SFILLCFLIYKYYKNREVYNLFEKGVHSLEESFLYLGSSFLGRNISVILKQQHKLYQS
                     MIQEHKKIHSEHLTFINQWIHQMKTPISVISLQLQDYEGEEVTENIRKEIDRLNKGLD
                     MAMHFARADNFQKDFIVEKAKLNEIVSSIVNEEKRLFIKSGMIPKIQVDKFTYVYTDV
                     KWMKFIIGQLITNGVKYSKDYSNYLTIKSEENNKYVILSIIDEGIGIVSKDLKRVFAP
                     FFTGENGRKFGESTGMGLYLVKKVCDDLGHKVSIKSEVGKGTEVSIYFNKGVNSLIKM
                     "
     gene            complement(100694..101386)
                     /locus_tag="KR231_000086"
     CDS             complement(100694..101386)
                     /locus_tag="KR231_000086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011987369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBH0002506.1"
                     /translation="MSYKVYIVEDDISISTLLKDYIEKYGFEVIVEENFDDIMITFES
                     FKPHLVLLDVNLPKFDGFYWCRCIRQQSNLPIIFISARDGNVDQIRALESGADDYITK
                     PFYYDVVMAKIKSHIRRVYGEYSPKIDERIVELDGLKFYPERLELELNGENLIITKKE
                     GILIECLIKRYPKVVSRDYLLEKIWDDIEFVEENTLNVNVSRIRKRFEELGIDNAVQT
                     VRGLGYKLNKNW"
     gene            complement(101700..102659)
                     /locus_tag="KR231_000087"
     CDS             complement(101700..102659)
                     /locus_tag="KR231_000087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NrtA/SsuA/CpmA family ABC transporter
                     substrate-binding protein"
                     /protein_id="HBH0002507.1"
                     /translation="MKLKKLLIGITILTLATASLAGCAKKNNGEKLSEINLTYVKSPL
                     NVPSIIQKQDDLFGKEFKKDNIKVNFHEITTGPEQTQALAAGEIDFLHALGGTSALIA
                     ASNGVELKILNTYSRSPKGFMILTNNNSIKSAADLVGKKVAGPKGTILHQVLISALDK
                     EGLSMDDVEFVNMGIPEASAALSDGSVDAALIAGPAALKAMKSGSKLVANGEGLVDGI
                     IVTAVSTDFAEKHPEIVERFMKVEKETLEYVNNNFDEAMEKVAKEVDLSLEETKELYA
                     WYDFSLDITDKDISSLEDTQDFLIKNKLQEKKVNIKELIYNAK"
     gene            complement(102692..103570)
                     /locus_tag="KR231_000088"
     CDS             complement(102692..103570)
                     /locus_tag="KR231_000088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH0002508.1"
                     /translation="MNNLVCDSGYIIRNLYKSYKVDNKEHVVLSDISLNIDRNHITVI
                     LGESGCGKTTLLRAIASLEGINSGEIRFINDNKEYRPNVGFVFQESRLMPWLNVSENI
                     AFHNQRKNTILNKVLRKFKHNKRIRSKIINDNFRSLETNDNLNKSNKYNRKSNIDVEK
                     YLKMMNLQKFKNSYPNELSGGMAQRVSIARALSFNPDMLLMDEPFSALDYFTRIDMQN
                     EVIRIHKSTNKGVIFVTHDIDEALKIGKKIVVFTDERKVKEFNIEDGYNRDLTSDYYI
                     KLKKDILMTMKSNKGI"
     gene            complement(103563..104345)
                     /locus_tag="KR231_000089"
     CDS             complement(103563..104345)
                     /locus_tag="KR231_000089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBH0002509.1"
                     /translation="MVNKFNNKFLRLVKSVLIFFIILLLWKITNYLGIWSDYILPSPE
                     KVYSTFLNMISDGSIFINVYASMKRVLIGFAISTAIGVPLGIFFGIYSGVYEYFKSLI
                     NFLRNTPPLALIPMLILWFGIGEESKIIIIVLASFFPIFTSTLKGIKNCDSKLIEVGR
                     VFEFSKLQIIFKIIIPNAILDIAVGLKLALGYSFRAIIGAELVAASSGLGYLISDGKE
                     MSRTDVVIVGIIVIGLLGIITDYIFSIIVKKVSKGKMVEAYE"
     gene            complement(104346..104975)
                     /locus_tag="KR231_000090"
     CDS             complement(104346..104975)
                     /locus_tag="KR231_000090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0002510.1"
                     /translation="MNKYLLINPVAERMYGEKFHLIKANLIKKGYIITECEPQLEYVK
                     KQYKEYTKKTENTMLDCRCPESISLLKRNNLINNFEVPMIEPILVRTCRVLYDKYIKS
                     KDDMLVVTCPCTQLRDFASEKFKDKGNAMFYTWKEFAEQEGVKSLGKIDESPIPLGYF
                     KDTFEKVLEVSSEDEILSEIQKIRNGFEDKYDIVEMFYCKDGCNNGDGL"
     gene            complement(105370..105996)
                     /locus_tag="KR231_000091"
     CDS             complement(105370..105996)
                     /locus_tag="KR231_000091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GyrI-like domain-containing protein"
                     /protein_id="HBH0002511.1"
                     /translation="MKYEWRKRDKELYLPKKNPVIVEIPEQKFIMLKGSGDPNSKEFT
                     EAIGVLYSLAYAIKTMPKKGIVPEGYFDYTVFPLEGIWDKGEKSKGLDVLIKEDLIYT
                     IMIRQPDFVTQDLLDKATDIVKKKKPHNLLEKVRFGSINEGLCVQMLHIGSYDNEPES
                     FDIMNEFCKKNKLIRKSYTHREIYISDARKVSPESLKTVLRFEVEREV"
     gene            complement(106072..107043)
                     /gene="nrdF"
                     /locus_tag="KR231_000092"
     CDS             complement(106072..107043)
                     /gene="nrdF"
                     /locus_tag="KR231_000092"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit beta"
                     /protein_id="HBH0002512.1"
                     /translation="MTFNLHKIHNAVNWNREEDGFTQAFWEQNVKQFWLPEEISVSKD
                     IKVWNELSNKEKELYKKVLGGLTLLDTKQGNNGIPSMMSLTENLQRKAVLSFMGTMEE
                     IHAKSYSSIFMTLLSNLEIDELFEWIETEPTLQRKADLVLAQYENTTNQEGLYLSMVT
                     SVFLESFLFYSGFFYPLYLSGQGKMVASGEIISLILRDESLHGKYIGLLAQEIYDSFD
                     KMDKEMLEEKMYSILYSLMENEIEYTNVIYRESGLEKEVVNFLKYNANRALENLGFEK
                     LYTVDAINPIVLNGLSTETKTHDFFSTKGNGYQKGVYEELEDEDFII"
     gene            complement(107055..109154)
                     /gene="nrdE"
                     /locus_tag="KR231_000093"
     CDS             complement(107055..109154)
                     /gene="nrdE"
                     /locus_tag="KR231_000093"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422595.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit alpha"
                     /protein_id="HBH0002513.1"
                     /translation="MNWIELNNQVIIKNEQGKYQLEKDKEALSSYIEEFIQPKLRKFN
                     NLEERLKYLIDEGYYSKEVINQYSIDVIKNIYDMIDKHKFEFQSYMSANKFYQNYALK
                     SNDGKEILETYNDKVLIVALTLGNGDKDLALNLADKIVKQEFQPATPTFLNAGRKRAG
                     EMVSCFLLSVEDSTEGISYAISSSNHLSKIGGGVALNLSKLRASGESIKDIEGAAGGV
                     VGVAKMLEQSFSYFNQMGARQGSGAVYLTVFHPDFELLMDTKKINADEKIRLATLSLG
                     AIIPDKFMELAEKNEVAYAFYPHTVYKKYGVSLDEIEMDEWYDKLVNDSDIRKKEINP
                     RQMLTKIAQMQQESGYPYVVYIDTANREHTLKDVGIIKMSNLCCEIFQYQTPSEIEGY
                     GGKNEWGQDISCNLGSLNIANVMDNKTIESTVETAIRALSFVADSTDIKPVPTVSNSN
                     SKSHSIGLGAMNLHGYLVRENILYTSDDAIDFSNVFFAMVRYYSIKASMKIAIERNQT
                     FEGFDKSEYVKGRNSKVLSKYYEQSYLPKSEKVRALFEGIYIPTKEDWTKLLDEVKEK
                     GIYNAYLMAVAPTQSISYVQNATSSIMPITEPVEVRTYGDSTTIYPMPFLTNDNMLYY
                     QSAYRMDMRKVIDLVATVQNHVDQGISTTLFVTDEKTTRDIARHYIYAYKKGLKSLYY
                     TRTKMTRDTHECLVCSV"
BASE COUNT        36365 a        18879 c        12002 g        42161 t
ORIGIN      
        1 atttaaaaag gtagaatcaa taaaattata cttataaatc ttcaatacaa taattaaaat
       61 ttaataaaaa tataattgtt gatttaactg taatcttatt taattctacc taacttatta
      121 tataaaacta ttttttatag attataaaat atctaacttt catctacttc aaagaataca
      181 atacttctcc ttctcttata gtctgcaata ctttaatatc ttttattttc atagggtcga
      241 ttgtaagtgg gttttcatct aatattatca aattagctaa tttcccttct ttaattgaac
      301 cttttttatc ttcttcaaaa tattgatatg ctgcatttat agtaacaccc tttaaagcat
      361 ctaatgggct tatcttttca ttttctccta tttgtatacc tttttttgta attctattga
      421 cagcacacca tactgtttcc agcatattag gtgctattac tggtgtatcc tgatgaagag
      481 tgtaaattaa tcccttttct atagttgttt taagtgggct aatcttaaac gctctatctt
      541 ctccaaggtt tttgatatga atatcacccc aataatatgt gtgagctaca aaatatgaag
      601 gtatcatatt tattactttc atatcatcaa tctggtctgc tcttactgtt tgagcatgta
      661 tcataactgg tcttatatta ttttcactac tttgctcttt taagtttaaa actttctcaa
      721 acgcatctat caactggtct gctgctgcat ctccattaca atgagttaag agttgcatct
      781 tttcttttag tgaaatatct ataaactttt ctacttcttc atctttgtat ataggatatc
      841 cacaataacc atcatctgaa ttttcatatg gtctactcaa ccatgctgtc ttaccttgtg
      901 gagaaccatc taagaaaatc ttataacctc ctattttaaa tctatttata tattttttta
      961 taaactccct attattatct gctacagact tacttttttt caaatttaca tatcctacaa
     1021 catccatttt taatttattt tgatttgcca ttgcttttaa aatgttaaat tgattttctt
     1081 ccattaaacc ttcttgagct gttgtaatac catagcttag atatatgttc tgtgcttttt
     1141 caattgaatt aaaaatctca tttgatgatg gttgttttat tttagatgct acattaaaaa
     1201 atgcattttc ttctaaatat ccatttggtt cttcactgcc ttctactcta cctatatgtc
     1261 caccttctgg gtcacgtgtt tcattggtaa caccaagctg ttttaacccc aatgtatttg
     1321 caactcccat atgaccagaa gcatgtgaaa ttagtattgg attttctgaa gatgcactat
     1381 cgagtacact cttatctgga tgcttatttt cttctaaaaa attattatca tatgaaaatc
     1441 caattatcca gtctcctttt tttatattat tcgactcttt gaaatcctgt atttttttta
     1501 ctatgtcttt aaaactggtt gcatcttcta aaggaactag ctttagagta gtagcaaaag
     1561 ctatcaagtg actatgtgaa tctataaaag atggcatcaa tgtcttacct tgtaaatcta
     1621 taatttctgt atctttattt ttcaaagcaa atacttcttc ttttgttcct atctttttta
     1681 ttattttgtc ttttataaga atagcatctc cacatattga atcttccatt gtgatgatat
     1741 ttccattgta ataaattttt gctttcataa aattctcctt acgttgtcta ctttaataaa
     1801 tttttttcat tattttctgc ttaattatat tatcttcttt ataaactttt tctttagagt
     1861 ttaatcatat aaaagtttta tttttaatta ttgtttgcca agaagtaaat actattcatt
     1921 gtaaataaga caaattaata ggctttatac taattgaaaa aatattataa gttgttaaat
     1981 ttaaatatct aaactcaatt atatctgtac aattgtaatt ttttaaatca tgatgtatta
     2041 ttttaaatat acagttacat tattattcac aatataagta tcttagttct caaataacat
     2101 ctcatgtaat ctattcaatg caaaaaattt aaatattttt taggaggttt tttatgagca
     2161 aggaaaataa aaatgtaaga attgctgttg tccaggcgtc accagtcata atggatttag
     2221 aaaaaactgt tgaaaaagca ttaggattaa ttaaagaagc tggtagaaaa ggggcaaata
     2281 tcgtagtttt ccctgaagca ttcatacctg catatccaag aggtctttca tttggatttg
     2341 ttgttggaag tagaacaatg gaaggtagag aagattggaa aagatactat gataattctg
     2401 taccagttcc tagtgctaca acagatttat taggaaaagc agcacaagaa gcaggagtat
     2461 atctatcaat gggtataaca gaaagagatg gtaatgatat aaattgtacc ctttattgca
     2521 caaacttatt tttctctcca gaaggtaagc taattggtaa acacagaaaa cttaaaccta
     2581 caggaacaga aagatgtatt tggggagaag gagatggaag tactcttaca gtagttgata
     2641 ctccatatgg aaaaatgggt tcgttgattt gttgggaaaa ttatatgcca ttagctagaa
     2701 cagctcttta tgctaagggt gtaaaacttt acatagcccc tactgcagat tcaagagaag
     2761 agtggcaagc aactatgaaa catattgctt tagaaggaag atgttttgta attggatgca
     2821 atcaatatgt tgaaaaaaat acgtacccaa ctgaccttaa ctactataag gagctagatg
     2881 cagaaccaga aattatgtgt ccaggaggaa gttgtatagt tgaccctttt ggaaaatatg
     2941 tagcaggtcc tattttcaat aaagaagaaa tgctaatagc tgatttagac ctagaaaaaa
     3001 tagtacttag tagactagat tttgattcag aaggtcacta ttcaagacca gatgtatttg
     3061 aattaattgt tcatgaataa tctttttaca caaacatcta cataaatctt tttacataaa
     3121 aaaatgagat actcataagt aaatttcaag tatctcattt ttgcttaaaa cctataatcc
     3181 taattataaa tttattcacc tatatttttt ctaaatcaac tactgttctt ccaacatgtt
     3241 ttcctgccat tattgaatct atactatcat ttaactcttc caatgatact acatttacca
     3301 tatcatctaa atcatctaat ttccattcat ttgataataa atcccatatt tttaatctta
     3361 agttcattgg gcaatccaca gaatctatac catataaagt aattcccttt aagataaatg
     3421 gatatactga acttgtaaaa tcaactcctc ctgcattacc acaagttgtt actgctccac
     3481 aataattagt tgtctttatt gctgttgcta gagtatttcc tcctactgta tctattactc
     3541 cagcccatct tggtctaagc agaggtcttc ctgagttatc atccacttct gacctatgta
     3601 taacatcttt aacacctaag tttagtaata cttctttttg ttcttctaat tttcctgttg
     3661 aaactacaac tgaataacct aatttaatca atattttagt tgcaattaca gcaactcctc
     3721 cagtaccacc agtgactaat acatctccca tattcttgtc tacagaatct ataaatttat
     3781 acacagataa agctgctgta aaccctgctg taccataatc cattgcttct tttagtgaaa
     3841 gatttttagg aagtttaact acccaactag aaggaactct tatgtattct gaaaaaccac
     3901 cagaagtatt cattcccaag tcataacctg ttactaaaac ttcttctcca attttaaaat
     3961 catcacaact actagattct actataccag atgcatcaat tcctggtgta tgaggatact
     4021 ttctcgtaac acccttatta ccatttgcag aaagtgcatc cttgtaattt aaagaagaat
     4081 attttacttt tattaaaact tcgccttctg gcaatgtatc cacttctctt tcaactatat
     4141 ttcttctaaa atttccttct tcttctgtaa tatatagtga tttaaatttt ttattcataa
     4201 atttcctccc aatacattta gttttatgtt aaactaatta tagtttataa atagttttat
     4261 gtcaaactaa tttaaataga ttaaagattg gagaataatt tatggaagat aaatatattg
     4321 tacatttcat aagtaaaaca aaggctagta tgattaaatt cattgaaaat aaactcagta
     4381 aaaatggttt aggtgagtta atacctactc atggaaatat tttaactgca ctttatgaaa
     4441 ataatggaat acttacaatg aaagaaattg cagctaaaat aggaaaagat aaatccactg
     4501 ttacagtgtt ggttaataaa cttataaacc taggatattt agaaagacaa aaatgtacaa
     4561 atgacaaacg tatcacgtat ataaagctta caaaaaaggc actgcttata gaagatactt
     4621 ttaatagcat ctcaacacaa gttaaagaga cggcatatca taatattaca gaaaatgaga
     4681 aacaagaatt tcttagaatt ttaaaaaaaa ttaatgataa ttttaaaaat gctgactaaa
     4741 ttgagcataa ttatatctcc tattggaata ataaataaaa agaatcaaat attgtaaaaa
     4801 tttattgtga tagagaggta gaatatgaat ttaaaagata gtaaaactaa agaaaattta
     4861 ttaagagctt ttgcaggtga gagtcaagct agaaatagat acaatatttc tgcatctgta
     4921 gcaaaaaaag aaggattata tataatagag tctttattta attacactgc tgaccaagaa
     4981 aaatcacatg caaaacaatt cttttctaaa ttaaaagaat ttgctggtga aaatataagt
     5041 atatcaggag cataccctgt agatttatat gacaagacag cacaacacct taaagctgca
     5101 caacataatg agcttcaaga gtgggatgat gtatataaaa actttggaaa aacagcacgt
     5161 gaagaaggat ttgaatctat agctaagtta tttgaaaata tagctgaaat agaaaaagtt
     5221 catggtgata gatttggtag atatgctact gatttagaag aaggtacttt attcagaaga
     5281 aatgaagata tacaatggat atgtacacat tgtggccata tacatatagg taaagaagct
     5341 ccaaaagctt gtcctgtatg tcttcatcca caaggatatt tcttagattt taaaaactca
     5401 ttatttgaat aaattaaggc aataattcta tttaaacaat ttactatatt tatatcaagt
     5461 atttttataa atactgtatt atcttaataa caataaaatg aaccattgat attactataa
     5521 gtagaaaatg tagtttaaat acaatttata gtaattcatc atggttcatt ttattgttta
     5581 ctaatcccta taacctactt aaatctatct ttaactttta catactcaca taaaatctta
     5641 tctttaaact aaatatttaa ataaagtgta ttttaagtat attattataa tacattatat
     5701 aagataatac actatgataa ctttatactt atatcattta tttcttttgt caagtcaatc
     5761 tcaataatct taactacatc tttttcaaac tttacttttt tataatccag acatcctact
     5821 acgaatggaa ctccaaactt tctaaacaaa taaatctttc cactttcatt gtatattgat
     5881 gtaaaatttt cttctattat attcactatc aattttaact cttcaaaagt tattatagat
     5941 ttaactaaaa acttctctat tatgctcaat ataagcagtt cttttttacc tatgctttgc
     6001 tcttttttat ataaattttg aaatatttct ttggtataat tacatataac ttctttactg
     6061 agaataaaat caatgtcaaa ttctttatta atatcctttt tcataaacat atttgcaata
     6121 tcatcaagag aagtctcttc tttcatagac aatattaact ctattctttc tagtatttta
     6181 tctcttggaa agaaagtctc ttgacctgta aaagctgatt tttttataaa ccattcctct
     6241 ggtattatgt tttttctttt ccatctatat aattgaccat aagatatatt agttttgctc
     6301 aataaatctt tcttagatat taattcttcc ataacttttc tagcccacct ttatactgtt
     6361 ttttacagta gaattatctg aaactgataa attatcactg tattcaatat ttccaacatc
     6421 acaattatct actagagata tgcttttacc tcgtatatct tttattgatg catcttctaa
     6481 ttcaatagta tctccctcta tcaaattaca tttaaacttt cctgaaaaaa tattaatgat
     6541 tttaattaat gaaaaagcat ctttgcttct tcctattttt atattagttg cccctatctc
     6601 tttacaataa gaacctcctc ctgaataaac atatatattt tctccattta aaagaccatc
     6661 acattttatt gctccatata cctttatatc ttcacattct atatttgatt tatttctcat
     6721 ttcgccatag atttttatat cttgtgcata catattttca tttacactta attgtcctct
     6781 tattgtaaca ttattacatt taagtttgcc atccactttc tgttgagcag ttataactaa
     6841 gtcatctatt tctgcatctc cctctatatt aagttgacca ttcactctta cacgctctgc
     6901 tttaagattg cctcttataa tagtttttcc gttaacaaca aaatttttta tattgatgtc
     6961 accttcaaat tttgcatctc caagaacttt tacttcgtta cttttaacat ttccttttga
     7021 tttagagctt cccacgattt ttatattttc atactcacca ctacttataa agccttctcc
     7081 aagtattttt atagaccctt tttccatatt attacctcat tttaaatttt atttttaaac
     7141 ctacttatta cttatccttc tttaatttta ttttttcact tatattcttt atttcaccaa
     7201 ctattgaatc ttcatcaatc tctatacttt cactgtactc caaactttct acataacatc
     7261 ccttgcctat tttaatattt tttcctctta caactttgac ttcactattt tctaagctta
     7321 tttcatctgc ttctataata tttgcaaaca atttactttc tgtatacttt ctaattgata
     7381 atagacctaa acttatcaaa tttgaagaca ctttttcaaa gttgatatgc tttttttcta
     7441 gcatacgaaa ttttttgcaa taatctccat gccccttttt tatatttata ctacttgctc
     7501 caacttcatt aaaattagaa gttccattta aactaatatt aacttcttca caattcaaaa
     7561 atccattaca ctccaagatt ccacttaaat tgatattttc acaatctata ttctcatttg
     7621 cttttaaata tccttctcca tgaataatat cagattttat acttccttct acattaataa
     7681 ttccactagt atcaatttca acagaattaa tatttcctgt acatctaaga agtcccgata
     7741 tctcaacttt tgatgccagt atgtttcctt ctactttact taaaccagat gtaaaaaatt
     7801 cattacattc tgttgtccca aaaacttttg ctgaaccaga agaatcaaat ttactacatt
     7861 ttacacttcc ttctattttg cctgttcctg atatattaac attatcaaaa attccacctt
     7921 tacattttcc aacaccatca aatcttagtg aacttaattc ttcattcata atgatatcct
     7981 ttctttaccg tattttatct ttaaacctaa tataacaaaa cattgttacg ttgtcaagta
     8041 tgataataat acttaataaa gcaactatca tttattttct ataaataggc ataaaaataa
     8101 tagggaaatg ctttatttaa actataaatc taatttctta gattgtggtt taaataaaat
     8161 atatccctat tactcaatct ttatatattc attgtataaa cttctaaaat ataagtcttt
     8221 aaattctact gtcaatactt tttatacact gtttgtgcta tcatctcaca cacctaaagg
     8281 agtgggcttt ccacactatt ctgtaaccta caagacacta tcttcttcta tctattgata
     8341 aatttttcta ttacatcagc tagtctctcc atatcagttg gataaacttc acctatgcta
     8401 cctattctaa atgtatctat atcagtcaat ttacctggat agataacaaa tccattatct
     8461 tttaaataag tataaaattc cataaattca aactttgcat ttttaggata taagaaagtt
     8521 gttattacag gtgattgagc attatcattc accaaagtat caaatcctaa agattttaat
     8581 cttgaagcta ttgtaaactg attttcttta tatctagcat atcttttttc aacagaacct
     8641 tcttcttcca attctaataa agcttgataa aaagctctta caacatgtgt aggtgaggta
     8701 aatctccatt taccattatt tttctccata gtctcccatt gcgcatacac atcaagagat
     8761 aatgatttag ctataccttt acatttagat aatttctctt tattagctat tataaaacca
     8821 aatccaggta ctccttgtat acatttgtta gaactactaa ctaaaaaatc tatattaaaa
     8881 tcttcaacat caatctcaat tcccccaaaa ctactcatag catcaactat ataaattttg
     8941 ttatattctt ttgcaagttt ccctacctct tgtataggat ttaatctacc tgtagtagtt
     9001 tcacagtgaa ccattgatat atgtgttata tccttgtttt cttttaataa attttctact
     9061 acatttaaat ccactgcttc tatatcttta aaagtgcagt caacaaattg tatgttaaga
     9121 taattacata tatctttcat tctctttccg tatgctccat ttgcaattac aagaagttta
     9181 ccatcttttg aaatagtact tcctattata gcttctactg aaaaagtccc acttccttgc
     9241 attaatacac ttgtgtattt atctgtattt tgggttgcta gagatactaa tcttcttcta
     9301 acatcttgta ctaggttatt atattcaaca tcccaagtac accaatcttt taacatagat
     9361 gctcttactg atttagtagt agatagtggt cctggtgtaa gtaatatgta atcattttct
     9421 ggtacaaaat ctgatttaat agtttcattc tctattttta ttagtatatc ttctaactca
     9481 gccatagttt ctattacaaa atgtgctcct gcctctttaa atttctttga aactatactc
     9541 atcttagctt ttaattcttc cttatccatg ttctctactt cttcttgtgt aagccctaac
     9601 tcacttgaac cttttattac agcaacactc cacattcctg catttacgcc ttcttttaca
     9661 tcacttattg tatctcctac ttttaccata gaactcatag gagacacccc taaagcttca
     9721 gcatttttat agcacatcca aggatatggt cttccttgag atacttctga tggtgttaca
     9781 agaaaatcgg gtgagtatcc tttctttgct gcatttggtt caactatgtt catcatctct
     9841 cttgtataac ccgttgtaga acctattttt aatccatttt ttctcaactt ttcaatagtt
     9901 tcaacaacat gaggaattgg agtcgtatac tcttctaatg tctcaaataa cattggctca
     9961 aattcagcat aaagttcatt tacatcatct tcagttggca ctttaccaaa cttatctgac
    10021 caaatattct ttattctatc catttcacac atttctctta tatggtctat ttttaatttt
    10081 cccataggtt ttcttgcttc ttccattgtt acatctatac ctcttctttt aaatatctct
    10141 ataaatacat taagaggtgc aaaacatcca taatctactg ttgttccagc ccaatcgaat
    10201 actactgctt ttattttttc tccatatatc tttttcatat ttatagcctc catagattct
    10261 ttttagaatt tttgtgtttt taattgtttt tacttttaaa gtataacttt catatgttaa
    10321 ttatacatca tatttaggtt aaatatatat taaatttctg tttttagttg tatttagttg
    10381 tttttatttt gtatcatatt cccataaaat cctaagttac aatctaaaat ttactttcta
    10441 atcttaatct atgaactgac tatattttat gaatttagtt gtattgagca tagttgtatt
    10501 atataaaact aagggtttat tttgcttcta tccatgttat atttatctca tttaacttat
    10561 ccttccattc attcggaggt tctacatcac aaataacaaa atctaattcc tctaaatctg
    10621 ctatcttata catactagca attcctattt tagaactatc acataataca aaactttcct
    10681 ttgaattttt tatatatgct tttgacaaca atgccttatt ttggtctata ctactaattc
    10741 caaaactatc aagtatacct tcactagata taaaagcttt atctacgtat aagtttttca
    10801 tagcatctat tgatattgga catgctgtcc tttggtgttt taaatttact tttccaccaa
    10861 taaatataac ttctccatca aacaaacctt gattctcgta agaaatcaat tttgacagaa
    10921 ctggataaga gtttgtaata atttttaaat tgtttacaga tattatataa tctacaatct
    10981 gcaaattggt agtaccttca tctatgataa ttgactcatt gtcatttaca aacttagctg
    11041 catatttagc aatactttgc tttttatcta ggttagtatt gtttctcttt atatgttctg
    11101 gttcaatcac tccataattt atttttatag caccaccata tacctttttt aatttatttt
    11161 cattttctaa ttcttccaaa tatcttctta ttgtttctga tgatacttct aatcttttta
    11221 ctaattcttt agtgtttacc ttcccttttg aatctagtaa tttaagtatt tctttttttc
    11281 tatctatcga atttaaagac attcattttc ctcctaaata taatatattt ttctcctata
    11341 atattacaat gatacctaag atttatgaaa tcatatttat gtattaaatt ttttacttaa
    11401 ttaaagttat tttcaaaaga ctttgtatta tcattaaaaa agtccatcaa atattagtat
    11461 cagatggact ttgtaaaatt ttattttata aattaatatt taaagtctaa ctactaattt
    11521 attttcttgt ctccaagaat tttactaaat tatttacagt agacatatct tttctctcta
    11581 aatcagttgg ttgaagctct atccctaatc tattttcaat ttcaagtaaa acttcaatta
    11641 tagctaatga gtctaaaagt tccgtctcaa ataaattaag gtctaaatct tctcttatct
    11701 catcagtccc taatacatct tcaaatattt ctataactgt ttcttgcata aattttcctc
    11761 cttaaaatta agctaaataa cctgagaata tcagcaatcc aaaacacaca atatggaatg
    11821 taatgaaaat ctgcactctc tcgaaccatt tatctttttt atgtttttta taaaatttag
    11881 attttcgctg atatatatca gttaacacaa gtgccaatcc ttggtataca ccataagcaa
    11941 cataatacca agttagacca tgccaaaatc ccattgttat catggttatc atctgagcca
    12001 catgagcagc agtagtcctt ttcttaaatc ttttctttct cattgatgac ataacaaatc
    12061 tagaaaaaat ataatctcca aaccatcttg aaagacttat atgccatctt gtccagaact
    12121 ctttcatatc tttgctgata aatggcttgt caaagtttat aggtacttgt attccaaata
    12181 tgtaccctgt acctatagca aataaactat atcctgcaaa atcaaagaac aggtataaac
    12241 tatatgcgta catataactt aaaatattta taaaactcat atctttaggt attcttgata
    12301 cccaatatgt atttatcaaa aatgctataa caaacttata acctactccc atgacaatat
    12361 tttttattcc tggcagtaag tattcttcta tatactcttt tctagagatt tgtttttcca
    12421 agtcctgttc aaatcttctt gacctatcaa taggtccaga acttaaagtt ggaaaaaata
    12481 acataaaata aagcatcttt gaaattttaa cttcttttat agctccatca taaatttcaa
    12541 taaccatttg tatagttctg aaatttaagt atgatattcc aataaatcca attattccaa
    12601 aagaagtaac tggagatatt ttatttatta ttattgggag cattgatgca aacaagaatc
    12661 cccaatatat gtatttattt ttagtttttc ttcttacata ttcatatcct ttaactatta
    12721 ttacttcaag aataataaat attaccaagt actttagttg gacatcaatt cctactatta
    12781 agaatatcat aaacaaactt gccaacatac cataatactt tatattcttg cccattagac
    12841 ctaaaattac tgctggtatt gatgttaata ataatatata aagataaaaa taatctccat
    12901 attgtgaaaa aatcattaaa tttcctccat aagtttcttt ctgtctattt taccattgat
    12961 atttgttgga aactcagaga ttattgaaat atttcttgga atcatatatg aaggtatata
    13021 ctttccaagt tcctttttta ttatcatccc atttttaata ttacttaaat cattcttttc
    13081 atttaactca acaatacctt ttaagtaagc aattttttcg tccttatata ctggtaaaac
    13141 tactgcattt tttacattat gtacttttct caaattattt tctatatctt ctatttcaat
    13201 tctaaatcca tttaatttaa tctgaaaatc ttttcttcca caataatata tatttccatc
    13261 taaaagatat cccatatctc cagttttata agctctccac tttacaccat ctatttcatc
    13321 atagaaaaat acttcatcag tcttttcttt attattgaag taacctttag aaactgatgg
    13381 tccaattatt ataatttcac ccttttcatt ttctttaagc tcatttccat cttcatcaag
    13441 tatttttatt ttacaatttg acatagggta tccaactgga agactttttt catcatctat
    13501 agccttttga gtcatatcat ttacacttac accaacagta gcctcggttg gtccatatcc
    13561 attgataatt cttgtgtttg gaaatctact cataagttct ttagtaagat tttttgaaag
    13621 tgcttctcct atgaatatca ttgactcaag gttaggaagc attttactat taaactcttt
    13681 ttcagttata catactcctg caaaagaagg agttgacacc catacagcta tatctgagat
    13741 actaaattgt ctaaatagtt ctttatagtc tgctaataca tcttttgata ttgaaaataa
    13801 tgtagctcca tggataagac cagggtatat tgttgtaact gaaaggtcaa aagaatatgc
    13861 tggttggttc attattactt tttcacttcc atctatgttt agatatgggc ttatccaatc
    13921 tgaaaagcta tctaaattgt ttgaacttat ttgaacccct tttggctttc ctgtacttcc
    13981 tgaagtaaat agtatatatg cattttcatc atcttttacc cagttttctt tatctaatga
    14041 ttttccctga tattcattta ttatataatt taatttatcc atatcaatta cattgatatc
    14101 tccaaaattt ctttcatcac taaagttaaa taataccttt ggttttatct ctttagtgac
    14161 ttcaaaaact ctatcaattg gaaaactaat atcaagaggc acatacgctc tacctgattt
    14221 taaagctcct atcatacatg ccattatcat gttttcttta tttccataaa ttactatagg
    14281 agtatcttct tctttgtata catcctttag aaatactgat atagcatctg aatattcatt
    14341 taaatcttta taagaaagtt tatctccatt acacattagt gctgttctat ctgtatttga
    14401 atattttttt attccttcaa taattttcat ataagaatgc tcctttaaaa tccgttataa
    14461 ataaatggca attctttaaa tggagtaaat gttagaactc ctatcgccaa tattataacc
    14521 atagttaaac aaatactagt taacaaatct ttattgttct ttaaatattt taaataatct
    14581 ctcacagaca tctacccatc ctttcgtacc aagatgcatt acatccctta aataatactt
    14641 atctgaccct ttatctttaa ggtttagaac ttcaaagcct ttgctttctg ctattttttg
    14701 tgctttatcg tagtactgat ttctttcttt ttcagaaata ccagtcaaat tatagaattt
    14761 atccatactt gggattaata caacaactgg cttaatacct aagtcagtac atacatttag
    14821 catcagttta taattttcaa actccttaga tgttaataaa tttacatctt tgtctcttcc
    14881 tttgtattgc tctataccat ctttaaaatg ctctttataa tagtacttat caatatttag
    14941 tggattttta ccaactcttt ttttagcatc ttcaatggct ttctttctct catatgacca
    15001 atttattggt ctttttcttt ttgttgctct ctttttatct agcttaatta atcgtttata
    15061 aagaataccc ttttctttaa gagctataca atactttctt ccttgaaaat aaggctctaa
    15121 aagcaccttt tcagcttttt caggaaatgt cttaggctca tatagcttag catataatgc
    15181 ttctgcttta tactcgtcac ttccccataa taacttactt gatttttttg catattcaat
    15241 cttattttgt ttagatattt ttggattatc taaaaatcga taaaattgta ttggtgaaaa
    15301 tctagactga taatggtgac ttgtgactcc gtctttttcc ataaaccatt gcatagaaat
    15361 taacaagaca actttcttat tatcaatatt aggattcata cttcctaata ttgcagcatc
    15421 ttgtaatgtc tgagtatagg ctctcccaat tgcaaacacc ttatttttac tcctatttgt
    15481 attaaaatag tactttggat gttgttttgt tgaattacta agttctgatg accccaaaat
    15541 cataatatcc ttttctctta aaaaatgatt atttgctgta acccctttat cttttatatc
    15601 acttaaagta tcatccataa ttggaagtag atttttctcc ctcaaaagtt catcagtttt
    15661 agaatcaaga aatttgtcta acccaaataa aaatactacg cctattataa aaggtgtaat
    15721 aaagtatatc aattttctca tattttctct cctctaaaaa tattcaaatt tatgttatta
    15781 ttaatcatat tagttttgat atgtatattc aactacaaaa ttgtaataaa atcgtcaaaa
    15841 ctttttttga tactgttaca aaattgtaaa aaaaaagaaa aaaacgccaa aaataaattt
    15901 ctttttagca ctttttcata cttataattt gacattttaa cacttggtta agtatacacc
    15961 ttaccttaac ttaaaattaa atttatttaa gaatatatat tataaattct tatattttct
    16021 aatataaact atatactatc agctggataa acaatactac tttgtcttct tatctcatcc
    16081 ataatttcca ttactattat tgaattttca tgagaattta tatttgattc tattttattg
    16141 ttatttataa gacttataaa ctctacaagt tcataataca ttccttctat ttctctaggc
    16201 ttttcctctg ctttttcttt tggaatagat atatcttctt ctcttccatc tctgtattta
    16261 ataatagctt tttcaaatag attaagcttt tcaattatta tacttccctc ttctccctgt
    16321 atttcagatg gtatataaga atcagctact ttagaatact gaattatcgc atccatatca
    16381 tcatattgaa atacagctga accttctcca tccactccag tttgaagtat atgagaaact
    16441 gcctttacag tttttggagc accaaataaa ttcaccatag gatgtataca atacactcct
    16501 atatccatta aagctccatt tgacaactct tttttaaagg cattttctat aattccattt
    16561 ttatatttat catatcttga agaatactga caatagcttc caaaaaatct tcttattttc
    16621 cctattttat acaagttttc tttaactgct ttaaagtttg gaacacatgt aattctcata
    16681 gcttccataa gcaatacatt attatctttg gctgttttta tcattgattt gacttctttt
    16741 aaattagatg ctaacgactt ttcacaaagc acatgttttt tgtgttttaa acaagtaatg
    16801 gtttgctttg aatgtaatgc atttggagaa gctatgtata cagcatctat atccttcgat
    16861 ttagccattt gttctaaatc atcaaaaaaa atacttgctc catatagagt tccaaattct
    16921 ctagcttttt ctaaatttct agaatataca gcaaccaatt caaagtcttt aaccctagat
    16981 gcagctctta gaaatatatt tgctatattg cttgtcccaa caataccaaa tcttatttta
    17041 cccatcataa atcactcccc attttctaca ctttatttta attttaataa aaaactttac
    17101 aacttataga tatattataa aataatttta tcaaataaaa aagaaagcta attttaaatg
    17161 atttcaccat tttaacatag ctttctttta actacaatct aaattcaact tatattttta
    17221 aagttatctt tctactatat ctttatttcc cctcaaaaat tttatagtaa gaatttcatc
    17281 cacaaacaat gttactaaaa gtatagttac aacaattggc caataaggta ttataagact
    17341 atataaacta tcaactatat acacttgaaa atatctaact ccaataaatg tcaatatagt
    17401 ccaatataca gaaaacttta gacatactat tcctctacta ttgtacttat aatctgaata
    17461 atcccaatag accttattaa aatatacttt cataagtatt cctgtaatat attctactac
    17521 tgtcggcact actagacata ataaaagcaa tgcaaatata ttattggggt caataaatct
    17581 tgagacctct attataatcg acattgcaat tgcatacatt ggtttaaatg gaccatttaa
    17641 aaatccatct tcttgaaaat gcccttgttt ataataacta tataagtttt caattatcca
    17701 acctataaaa ccatacaaga aaaaattaaa taaaaaatat aatagagaac ctacattatc
    17761 catgaatatt cctcctagct gtttatactt attttttctc atattcatgg atttattcta
    17821 aatcaaagaa attatattta atttatttaa ttaatacttt atattataga ttgtgacatt
    17881 ctttagagtt caaacttttt aggtattctc taacttccag taaattttca agtatcttat
    17941 gtgattgtga tttaatttgc tcatctggct cttttaaatc tggtacattt atacatctta
    18001 taccaccatt gtatgcagct tcaactccca taggcgaatc ctctatgaca atacaatttt
    18061 tgggattaac atttatcttt ttagctgctt ttaggaatat ctcagggttt ggtttcgagt
    18121 ttacaacatc atctccacaa actatagcat caaagtaatc ttttaaattt gccttagcta
    18181 atctctttac tgctctttct ctctttgttg atgttgcaac agccattttg tatccatttt
    18241 cctttaaaaa agagattagt tcattgactc ctaatttgat aggagctccc ttcctctcca
    18301 taaattcaat catattttta gttttttcgt catataaatc tattattggt acagaactat
    18361 cgtatatatc tgtaagacct tctattattc ctttacgatt tcttcccata actgatgtat
    18421 aaatttcctt agtcatagta tatccatact tttcaaacgt ctccatccaa aattcaagag
    18481 aaattctctc tgagtcaaac aaaactccat ccatgtcaaa aataattcct tctacttttt
    18541 gcatacaatt cctccaatat tttttgatat aattatatta cactttttat gattaatttt
    18601 acaaccctca atttatccaa ttctaatatt gtaaaattgt aattttcaaa agttacactt
    18661 tggtttactt taatatttga accaagcata taggatatcc atccacctat actgtcaaat
    18721 ccatcatgct ctatatcaag tccaaaatac ttattaatat agttgataga ttcagttcca
    18781 tcaactaagt aagaacctgc tcctattttc ttaatatgag tctcttcttt atcaaattca
    18841 tcttgaattt ctccaactat ctcttctagt atatcttcta ttgttaccac accagatgta
    18901 ccaccatatt catccacaac tatagcaagt tgaagttttt cctttcttat tctctcaaga
    18961 gctttatcta tagttaaatt ttcagatata tatataatat ctctcaatat ttcttctagt
    19021 tcaattttat tttcatttat cttttgattg tataaatctc ttatatgtac aaaacctaat
    19081 atatcatctt tattttttct gcatactgga tatcttgtaa caccttcctc ttttaaaata
    19141 gctaatatct tttcttcaga atcactttca tatatacata ccatatcagt tctaggaacc
    19201 attatctctc taattttctt ttcttcaaat tcaaaaatat tatcaactaa tctttgctct
    19261 gattcatcta taagtccact tttataactt tcttctacta atagtcttat ttcgtcacct
    19321 gtatggggtt catcaacctc atcagcttgt gaatatccaa atggtttaag aaataaatca
    19381 gtacttaagt tgaaaaaata tattattgga tatgttaact tataaaatcc tactaataaa
    19441 aaagatgtac tcaacattat tttttctgta ttataaagtg ctaaagcttt aggaaccaac
    19501 tctcctatta caacctccat cattgttata attaaaaaag aaatggaaat tgatatagta
    19561 tatataatac tttcactaag attaaataca cttactattg gtaaaattaa ctctttaact
    19621 gtagattctc ccatccaacc taatgcaagt gaacaaagtg ttataccaag ttgacatgca
    19681 gaaagatagg aatttaagtt gtcttttatt attttacatc tttttgcatt attattacct
    19741 tcagttatca tggtatcaat cctagaacta cgaagtttta ccatagcaaa ttcacaagct
    19801 acaaaaaaag catttatcaa aacaagcatt actataagtg ttacttttaa taactcccgc
    19861 ataaagtata ggttcttata atgtaagaaa tctataagaa ctcaaagttc cccccttata
    19921 ttaataaatt taatttataa tatatattct atcatattta ttaatatatc ctactttatt
    19981 acaaataatt tttataaact aaataacccc ttttaatatt tatgactggc tatttgataa
    20041 atattaaagg ggttatttag ttatcatttt ttatttctaa aaatcttttc tcaaatgatt
    20101 tagttatcta tttatccaat tctttacata atttaatgat taaaaatatt aattttttca
    20161 ctataaagta taaatattat ctgattatta aaataaatat taatactata aataaaaacg
    20221 aagcatgatt tttatttaaa taaatctcaa acttcgtctt tacttactta gatatttatt
    20281 tactttctaa atcctattat ttttaaaacc ttatcttttt aatacttcac cacatttatt
    20341 ctcagtaatc tctccatttt ccaacgcaat ttttccattt acaattacat attcaacacc
    20401 attggctagt aattgtggct ttgaaaaatc aatatcttct gacctagaat aactatagtt
    20461 atccatgtca ataactgcta tatcagctat caacccttct ttaagaatac ctctattttt
    20521 tattttaaat tgcctagctg gtaatgaagt aactcttctt acaatctctt ccaatctaac
    20581 accagacttt ctgtacatat tgaagaaaat tggaaaagct cctcttcttt gtagttcaaa
    20641 ccatgacata tccccaccca cactaaacaa acaatctgaa ccaaccataa caaatggatt
    20701 atcaattatt ttatcatcat gtagtttatc tgggaaatca gctctataca ttcctcctaa
    20761 acaaaagata agttcttcgt ctccatctaa aagtaaatcg agtaataact tgtcttcatc
    20821 tattcctttt tgtgtagcta tttcacgtat tgatttcttt tccatattaa tatctttagt
    20881 gtttagaagt attatactcc ccctatctcc aagtataaat gcttctttta atataagtgt
    20941 tcttccctct tcatttctaa gagcatccat taccccattt atacctaatt caaatagact
    21001 agatgatatt gccataataa attgaattac tctttttttc ttcatacaat gcccagaact
    21061 tcttggtact gtgtcaacca ttatttcaac accattatac ctagccttta atatctcatc
    21121 aaatgcttct atttcaactg gacttaagtg agatacttga accctagcac cacttttttg
    21181 cccaacctct atggcttctt ttactgcatt atatcttcct atgtaatctc taatatgaga
    21241 tgtatatata ccatcatgct ctttaatctg ctttgcaata tcaacaagtt catcaatatc
    21301 agcatactta cttggtatat atgccaatcc agtagatatt ccaaaagcac cacttttcat
    21361 tccatcattt attatatctg taatttcatt tttttccttt tctgtaggag gtctatcctt
    21421 agaacctccc ataacactcc atcttatagt cccatgcccc aacaagaatc ccatattgac
    21481 agaaatacca cttttagata taaggtcaca atattctgta aaattattcc aacatttatt
    21541 tttatctata agatactttt tttcttcttc aagtaataga ccatttttat acatatattc
    21601 atatacattt tcagaagaat atggtgttat agaatgtcca caattaccat ttatagttgt
    21661 tgtaactcct tgttttagaa acttttcaaa tttaccatct agtattgcta ctatttcttc
    21721 atgaacatga gggtcaataa atccaggtgt tataactttt ccacaacaat caatctcttt
    21781 atttgtattg ctatttatct tagaatctat ttttgctatt aagttgtctt taattgctat
    21841 atctccataa aaaccaggat tacctgtacc acctattata aatccatttt ttaagattaa
    21901 atcatatatc aaaatattcc ctccttaaaa accaattttt aaataatctt aatgtaattt
    21961 ttatatttga aaatcaaatt attatatttc atatttgaaa attcactatt atttcattgt
    22021 aattagtcac taagcttatc tttatacata gctcttgcaa ttaacatagt accaaataca
    22081 catataagaa ctactagaga ctgtggtatt ataccttgct ttgataatat aatagtcaat
    22141 acagatatta caattgctac taggcctaat tttttatctt gtaaaaatac ttgtccaaaa
    22201 actgacccaa atagagctgg taaaattaag tttaattttt ctactacttc agctggaatt
    22261 ttagatagta cgcttcctcc taaaattacc cctatagtta gtatacttat attcactaaa
    22321 atagatacag ctattcctat tgtagatatt atcgagcctt cttctgtacc tgattcaact
    22381 tctgctgcct tttgagctgc tattgaacat ggtagcctca tattagatat attaccagaa
    22441 agaaaactca tataagttcc tgggatacct aagattggtg aataagaaac tggttctatt
    22501 atgtaatttg gagcactcat actgacaatt gccattgtac ttgctaataa tgctgatatt
    22561 ggaggcataa taccaaatcc aaagctcaaa attattccag gaactaatgc tgctataatc
    22621 cccaaagata gtgttagtct tccatacctt atcttaaaag gtaaatattc ttcattgtat
    22681 atagatttta ctttactcat aaaactcccc ccttatatta ctgaagctat tatcattccg
    22741 ctaaacattg atattgtaag cccccactct cttaaccatt ttatattttt cttcttttca
    22801 agcatacaca atattaccat tatagccatt ccacttatac atgcaattgt tccattatca
    22861 aaacgcaaca ccctatcagc atttagatat gcaaatgaac ccaacattgc tcctagagat
    22921 attattggta taaatgattt cttgccacta gatataacat tggttatctt atctagttta
    22981 tgtccaaata gtaatgtgaa tattatccat cctaaagaac ctaatatcat agtccaaact
    23041 gcatttgtaa atgcaagttt tgtcatttca ggagaaccta aagttatacc taatgcatct
    23101 gttccaaatc cggctgacat tgattcaaaa attacagaac ctataaatga taatctcatc
    23161 catgctatag gcccacccat agttactata agcgatacca ttccagcaaa tatagtcatt
    23221 gaaggcccaa tagctgaaat agcactactc ttaacagctg actttatttg tttatctgtt
    23281 attcccattg ttttaccaac tttgcaagat tttatagcaa atataaggga ttgtaccact
    23341 actattgata ctgctactgt actcgctatc cacaaaagtg gatgattagc taattttaaa
    23401 taatccattt ataaaacctc cctataaatc ctcaaatttt attaatattt ctaatatatc
    23461 tatttccaaa cctgttttag tactctaagt atatttccac ctagtacctt ctctatttcc
    23521 tcatcactat atccatgctt tactaaatat ctaacaatgt tttttgaagt ttctgttggg
    23581 ttctcaagac cttttacata ttctactttg ggatgttctt ttgttcctgt tatttttttt
    23641 atatcaaatt tagcagctag tactgagtgt aattttacat ggtcgccata tactgtatct
    23701 ggtccaaaag ctacatggtc tattcctact aaatttttaa tatactcaaa atgttccata
    23761 aatgactcta ttgaatgttc tttattcttc tctgttattg tagtatgagg tgctgcttct
    23821 acacctataa cccctccttt tttagcacat gctattaata cttcatctgg agttagtctc
    23881 tttgtgttcc ataaacttct tgccccaaca tggcttaata ttattgggtc cttgctatat
    23941 tctattacat caagtgtagt ttgaactcca acgtgagagc aatctattgc cattccaatt
    24001 ttattcattc tttcaacagc tttttttccg aaatttgtaa gacctccatc tttctcttct
    24061 tttagtcctg aacctaatgc attggattcg ctatatgtta tacccattaa ccttatacca
    24121 aatccataca gtatatctat tctatcaagt tcattttcta ttggtgctgc accttctaat
    24181 gttggtatca atgctacttt accttcactt ttagctctgt atatatcttc tactttttcg
    24241 cactttataa caaaatcttg atgagctaaa tcacatagtc tcatgcctaa atctattaat
    24301 atatcatccc atttccaccc tgaatttgat gttatcgtac atacaccatc cattaaatta
    24361 tcaaatatag catcataata tcctcttgat aatgcttcat aagcacatct ttgtttacct
    24421 tccctattat attcaaatat atctctttct aggtgttctg gaaataatac tggatgttca
    24481 tgtaatgata taaatatttt ttcatccact atacttttaa ccttagcttc ttgaatatca
    24541 tctaattcaa taaggtattc tttaactctt ttatctcctt tacacatctc aatagatgaa
    24601 atatcttttc ctttttctaa ataactatag gcttcatatc ctttgtaagc tgacttcata
    24661 acaacatcct ccaagttcta caatttttta tatttttcct atgtagcaat tgatgtgcca
    24721 aaatataaat tttaattgta taataaatct tgcaaaaaat aaaaacagta gtaaggttga
    24781 tatttactac tgttttatta aaaataatct tcttagatta tttattcaat atttttgaat
    24841 tatcttaatc ttaaagataa ttttatttat ttctatccat tatagggatt tttttagggt
    24901 gttttgcctt tttagtcccc tatatcactc ccttaatttt tacatatgat ataaagttct
    24961 ttccttcatc agttataaaa ctaccttgtt tttttactcc agataaaagt aaaccatggc
    25021 tctttaactt atctattctt tttctaattt ggtctacact taaaactata tctttttctt
    25081 ttaaaatctc ttgcagttta tttcttccta ataatatatt tttattattc caagtttcta
    25141 tactggtcaa tatacatata ctttcctcaa agaaattaga ttgtttgaaa tctaagataa
    25201 ttgaatcgaa attttcatta actaaagtat tgtttttttc aaatctaaat tgttctggca
    25261 aatgctcgta atctactcta tcttcctcaa ctatagtatc aatataataa attaaatttt
    25321 taagctctct tacatttcct ggccattcat acaatgttaa agcttgcatt gattcctctg
    25381 taaaacattt gttgctattt atttcatcta aaaaatactt acttataaga ggtatatctt
    25441 ccttacgttc tctaagtcta ggtatctcta tatgtaatac attaatccta taatacaaat
    25501 cttctctaaa agaaccttct ttaatttttt tctttaaatc tttatttgtt gcagctataa
    25561 ttctaacatc tattggtata attttacttc cgcccattct cataacttct ttttcctgta
    25621 atactcttag caatctctgc tgtacatcta aagatatatc acctatctca tctaaaaaaa
    25681 ttgttcctgt atgtgctctt tcaaatatac ccatttttcc accttttatt gctcctgtaa
    25741 aacttccttc atcatagcca aaaagttcac tttcaataag tgtatctgac aaagaagata
    25801 gattaactgc aacaaatggc ttgttttttc ttagagattc attatgtatt gcctgggcaa
    25861 atatttcttt tcctgttcca ttttctccaa gtatcaacac agaaaagtct gtagttgcta
    25921 tttttcttgc aatattaatt ttttctttta ttattttact ctcacctaca acactctcaa
    25981 atgtatactt tgatacaaaa ccttttgact gaagtttatt ttgaatcttg tcctcaagca
    26041 cttgaattgc acttatattt ttaatgctta taatactctt tattcgttca ttattttcat
    26101 aaacatttac tttattaatt atcagttttt tgttatttaa atttactact tcatcattaa
    26161 cttcatcttc ttgaaaaaat atttttttga caaccttatc actaaataag tccataaagt
    26221 tattagatat aatttcattt tggtctattc caactagatt agaaaatact ttgttgcaat
    26281 atataaattt tcctaattta tcaacagaag caataccttc atctataatc tccaaaaaac
    26341 tcttcatggt tttattcata gttgtataat acctatatcc acttactgta tcttcattgt
    26401 atttttcctt aataatatgt agtttatcta tagatatatt tagttttgta aagatttcta
    26461 taactgtatt tatatcaatt accttatcac ctatgtcaat tatttgcttt atgttttgtg
    26521 gtatgctgtt tctgcttccc gtaataattc caatctcaca tttagattta tcacaacctg
    26581 gataatatgg tattagatta atatgaatta atcctagttt tctaattatc ttggcagttt
    26641 catctgctga ttctttataa gcatctataa ccataacatc agaatcattt tctatactta
    26701 ttatctgatt tatattttca atatttatag tacgatgtac tattacaata ggtatatttt
    26761 tatcaatatt attatgtata tattccttta tatcattgtc tgaacatact acaagctcat
    26821 agcttgacag ttcaatattt atcctattta catataccaa gttatctata ttacaaaatt
    26881 ctccaaatat attttccaat tgttttgata tatctatatt tattttgtca tcagttgata
    26941 caaataaaat attatgtttt ttcatagtcc cacctcctgt ttaacgagta tagaaagtaa
    27001 taatttggtc tattgtagca ctttttaaaa aagttttaaa tcttaaaaat caaattttgt
    27061 accatttact attattttcc ataataaaat aatgtaagct atcttttttc acatataatt
    27121 taatttctaa aacggttagt ttgacattat tggaatataa acaaaaattt aatataaatt
    27181 cgttaatata ttaatacatt tttaagaatg acaaggaata aattataaca aattttagga
    27241 atatataata atagggtctc agaacttagt tacaagttct aaaaccctat ttgtttagtg
    27301 taaaaaacat cataaaattt agcttaaatc ttttcacata atattactct ttttctaagt
    27361 gataataaaa tttatctatt cctctaaaaa ctgtaaaaat ttctgattaa atagtttaag
    27421 ctcatcatag aatatagcat gaccactata ctcaaaagta tataaaattg aatcttctat
    27481 tttttcattc ataaaaactg caaattcata cggacatatt tcatctaatt tcccatgaaa
    27541 tataccagta ggcactctta cacattttaa atcattaaat aattcttcat ctcttaaaga
    27601 tacagcagtt ccaatagtgc caatacctga tgcactaaaa ccaatatcat taaaccatct
    27661 tctaaagctt tctggtggat ttgatgcaaa tactttttcg ccaaaatcgg ttaccatttc
    27721 tggtctatca gtacatgctt gtgctatcaa tttatttaca tcttcacgtg tcataccata
    27781 tggaaattct ggaggtcttt gtacaaatga tggtgcagca gctgcagcta ataccaattt
    27841 tgacactcca tatccattaa ataaactcat atacctaagt acgattgctc ctcccattga
    27901 aaaaccaaca agggtaaagt cttttaatcc aatagcatgt accaccttat aaatatcgtc
    27961 tgctaattgg ctataagtat atcctcctga tgttgcatca gatttaccaa aacctcttaa
    28021 atcaattgaa actgttctat atccgagttt tggcaatata tttgtttgat attcaaatat
    28081 cttatgtcct aagggccaac catgtataaa aagtacagtt tttttagcac tcggattcaa
    28141 atcatatact gctatgttta tatcattcac atatacataa tacatatcaa cagcaactcc
    28201 cttcaagaaa atgtatgatg gttattttat atatatgaat aaaatgatga ataactaaat
    28261 tttcaaattt atttacaata cttctctatt gccttttcaa ataaacttac atgaagtttt
    28321 tcatctagga ttattctatt taatatagct tttatataag ggtcttcaat aagacttata
    28381 tctttataat aattattaat agccacatgc tccaaatgca aatctagttt taatctgtta
    28441 caaatagaat ttccataaca tacaaaacca ccattccaat atgcaccaca agaacttgta
    28501 gaacctctat atacaggatt tccacccaat aatcttatag tctttgctaa tatctccata
    28561 tgtaacattt ctgttataga tatatttatc cacatttcac ttaactctct atgcgtttca
    28621 tctaaatcaa aattatggta tagatattga tttacactcg taaattcact tgatactccg
    28681 gcatagtcat ccatcaataa ttctgcataa tacttatttg gacctaaaac ttttatctct
    28741 ggatatggct catcacttga atatccattt cgcttgtgca tgtcataatg tgcatcactc
    28801 ataatatctc ctcctttaaa tttaatacat gatattaatt gtatgcatca cgactttttc
    28861 atataactta gataataaaa tctacttaaa taataaaaag ccatattaat taaaattaac
    28921 atgacctttt atccacaaaa ttacttttta attattcatc ttttccagct actgatagct
    28981 ctttaataac aactgaaggt gaacctatac tactcattgg aaattctaaa tcttccccta
    29041 tagcttcaat atctttcaac aggtcaaaat agtttcctgc tactgtaatt tgctctactg
    29101 gaaatacttt ttttccttct ttgatataaa agcctttggc agctaaagaa aagtctcctg
    29161 ttactgaatt tgcacctgaa tgaagtcctg caaagctagt aaccatcaat ccttcatcta
    29221 tatcctttat aatttcatct aaagatttat ctcctttctc tatataaaaa ttagttggat
    29281 atatgcttat aggtgatgaa tatgaagatt ttattccatt tcctgtagtc tttacacctg
    29341 ccttattagc cgtttttaag ttatgaagta aagttataag ctttccattt aaaacaactt
    29401 cttttttaaa tgtagctact ccttcatcat caaaaggagt agatgccata ccattttcta
    29461 aaagtgggtc atcaactatt gtaactatag gagatgctat catgtctcct tctctatttt
    29521 tcaataaaga taatcctttt tgagctgaat ctgcattaaa tatcccagaa aatgtgctaa
    29581 gcaaagatac catagcttca ttaagcaata tagttttata tttacctgat ggaatactct
    29641 taccacctac tttagataaa gcattatcaa caccaagttt tgctatctca caaggtttta
    29701 tttcttcaat agaatttgct atattatatc ctattccatc atatttttgt ccattgtctt
    29761 ctatgatagg aactacaaac cctataagca tattagtttt attgcttaaa ttaagacctt
    29821 tagtattaga tataccatta cttgatacag aataagatat agtacattta gataaattta
    29881 ccaccttatc tgaataagct ttagtctctc tttccatttc taaagctaaa tcaatcaact
    29941 tatctgcctc taaattttct agctctttag aataagtctt tacatcatta tagtgcttat
    30001 ctccttcata tataaattgt acatcttcat tttcaatagt gtttactcca tcttttacat
    30061 tttttatcaa catatcaaca gctttatcat ctaaaatttc tgtataagaa taacctatct
    30121 ttccatttac cttacctcta aaagataaac caaaagattt atcaagattg tatttctcaa
    30181 cttctccttc atatatattt atacttaaat tttctcctgt ataataatat atttcatact
    30241 cttcaaaacc ttcacttaga gcctttttaa ataatatatc tttaaaattt ttaagttcca
    30301 caattatccc tcctatcttc cacctacagt aatttctttt acccttatca taggttggcc
    30361 tacattagtt ggtatacttc ctgatgatga gccacacatc ccctgagctt gttttacgtt
    30421 attcccaacc atatctatat tcataagtat atcgctacct tttccaatta aactagcacc
    30481 tctaactggc tcttgtattt ctccattttt tattaagtaa ccttctgaaa ctgcaaaatt
    30541 aaactctcct gttacaggat ttacagaacc accacccatt tttttagcat aaagtccatc
    30601 tggtattgac tttataatat cttctggtct atcttctcca gcagcaatat aagtgttagt
    30661 catccttgaa gttggtgcaa atttgtagtt ctgtctacga gaacttcctg taggattcat
    30721 tcccattcgt ctaccattaa gtttatctat catataagac ttcaaaattc cattttcaat
    30781 cagtatattc ttttgagttg gatttccttc atcatctata ttcatagaac cccagtagtt
    30841 tggtattgta ccatcatcta tagctgtaat ctttgtggaa gcaatctgtt gacctaattt
    30901 atctgcaaat acagagttcc cctttgcaac tgatgtagct tccaaagaat gtccacaagc
    30961 ttcatgaaat attactccac caaatccatt atctattgct accatcatat tacctgcagg
    31021 acaattttta gcatgcaaca tagtatgcgc tactctagct gattcttttg cataatattc
    31081 tgggtctatt tcttcaaata tttcaaaccc tttacaaccc ccaggacctt caaatccagt
    31141 ttgattttca ttacccttag atgcaattga acttatccct agtctggttc ttattcttct
    31201 atcctcaaca tatatacctt cagtgtttgc aattaatatt ttttggtctt tatccaaata
    31261 gctaacactt acttgagata tatcattact aaattctttt gcactcttat atgcaacctt
    31321 cataacactt actttatctt tatttcctat tgaatttgga taaattttta tattatgtat
    31381 gttatttatt ttaatactgt catttaatat tacacttttt ccatcttcca atttacctaa
    31441 agcaacagca gctttgtatg ctacatccaa cagactattt aatgaattgt cacttgtata
    31501 agcatatata cttttcaatc ctttaaatat tcttattcct ataccataat ttcttccacc
    31561 tattgcattt tctactttat tatctattaa actaatagaa ttatttatag tgtcttcttc
    31621 aaaaatctca gcaaaatctc ctccagtaat tagacatttt tctaatacct tagaagctat
    31681 attttttgaa agcataaatt tacctcctac tttaaatttt taattaactt ttattcaatc
    31741 tttttacttg ttaacaaaca ttatatacta tattacttaa aataaggtaa ttatgaatat
    31801 attatacata tgttttatac taaaatgtta tcacatttta tctatacata cccatataac
    31861 tagataatta aaatgtataa tattatttgc tatagaaaat aatacactca tacataataa
    31921 attttaggag tgaagtatat gaatcaagaa tatgtaaaag gaaatcctat ttttaccaat
    31981 attaataaag ttccaagaca atttccatac cttactgatg atattgatac tgatgttata
    32041 attgttggtg gtggcgtaac tggatgtatt tgtgcctact atctagctaa aaacaatata
    32101 aagtctgtca ttcttgaaaa aggaaggatt gcacatggaa gcactagcgt gacaacttct
    32161 ctattacagt atgaattaga tgacaatttg atagatttaa cagaggttat gactctaaaa
    32221 gatgctctaa aagcatataa cctttgtact tcagcacttg aagaattaga tacatttata
    32281 gagctatatg gaaataagtg tgattatgcc aaaagagata ctctacttta tactgccaac
    32341 aaacttgaag ttaaggctat caaagaagaa tataacttaa gaaaagaaaa tggatttgat
    32401 gttgaatata ttgatgaatc cacaaaccct tttaactttg atttaaaatc aggattgata
    32461 gcaaagaatg gaggacgaga attagaccca tataaatata gtcaccattt gattgatgta
    32521 agtttaaaaa atggtcttca agtatatgaa aatacagaag taaaaaaagt agatttatca
    32581 aatgataagg ttactgctga agtatcgtat ggatacaaag ttcatggtaa aaaattaatt
    32641 gtagctacag ggtacaatac aagtttattt acaaaaagaa attttgcaac taagtcaaat
    32701 acttttaata tagcaacgaa accacttaaa aacatagctt cttggaaaaa caacatttta
    32761 attagagata actgtgaccc atataattat ctaagaacta ctaaagacaa tcgattaatt
    32821 ataggtggtg aagatgtaag ttttgatgat atagaaaatg aaactttagc caatgaaaag
    32881 tatgatattt tagaacaaag attgaaaagt atgtttaagg atataaaaga cattgaagtt
    32941 gaatataaat attgtggttg ttttgcttca actttagata atttaggttt tattggtcca
    33001 gataataaaa ataacaatct atggtattgc ttaggttatg gagcaaatgg tatactcttt
    33061 gcaatattag gaggtataat gttaagtgaa ttatatcttg gcaaacaaaa taaaaatatg
    33121 aaattattta aagtagatag atttgataaa tagatattat atattaaaag actgtaaaaa
    33181 gatgaaactt tataattcta aaagttaact ttgatacagt cttttataat gttcctttta
    33241 aaaatacttt atttataatt aaatataaag taaaatgtta aaatataact gataaaattt
    33301 agtcataaga taatatttaa gtttatttga tgaaatatgg aggaattatt atgaaggaaa
    33361 tactcgttat tgctcccact aaaggaacct atgaaaaatc aattcacata gttaaaaaaa
    33421 acaaatatac aaatattgat gttgtatttg gcaatctaaa agaaggtata cctcttgctg
    33481 aaaaaagtat taatcatggt actagaatta tcataagccg aggtggaact tacaatatgt
    33541 taaaagctac ttacaatata cctatagttg aaattaaggt agatgcttat gatattataa
    33601 aaagttacaa agaggtaaaa aattccaacg aaccatttgg aataattgga tttaataatg
    33661 tcatctacgg tttcgatatt atagaagaaa tattgaataa gaaaataact atgattgaaa
    33721 ttgaaaaaga agaagaaatt tatgatgcta tagaaaagta cagaaagaaa ggtataaaca
    33781 catatatagg agataccact gttgcacata ttgttaagag acttaattgt aagggaatat
    33841 taatcgaatc tagagaagaa aacatactta gagccattca acaagcagaa caaatactcg
    33901 aagcaaccaa ggatgaacaa aaaagaagat tacagataga agctatgaca gattttgtac
    33961 atgatggaat aataacagtt gataaaaatt ttaaaataac attatttaat aagagtgctg
    34021 aaaaaatatt tggtataaaa aaagaaaatg cactttatca taatgttgta gatgttatcc
    34081 caaacacagt tcttccacaa gtagttgaga ctatggaacc tcaaattggt gaaatacaaa
    34141 atatagggag tacaaaaatt attacaaata gagttccaat cattgttgat ggtcagattc
    34201 aaggggctgt ttcaacattt caagatagca aggagataag ttcttttgaa catacaataa
    34261 gaaggagctt attaagcaaa ggtctatctg ctaaatacac ttttgatgat ataattcatg
    34321 ctagtgaaaa gacaaaagat tgtatagaac ttgcaaaaaa atatgcttgt tatgatactc
    34381 ctatgattat tactggagaa tctggagttg gtaaagaact attttgtcaa agtatacata
    34441 actatagtaa gcgtaaaaat gcaccttttg ttgctgtaaa ttgtgctgcc atacctccat
    34501 ctctaataga gagtgagttt tttggttatg aggaaggttc atttacaggt gctagaaaaa
    34561 aaggtaaagc aggtgtattc gaactagcac atgaaggtac aatcttccta gatgaaataa
    34621 gtgaaatccc tcttgaactt caaggtcgat tattgagggt attgcaggaa aaacaagtta
    34681 tgagaattgg tggtgataaa gttattccta tagatgtaaa aattatctgt gcttcaaata
    34741 aagacttaaa aaatatgatg cgcaatggtt tatttagaca agacctttat tttagaataa
    34801 atatactaac attatatctt ccttcattaa aagaaagaaa agaagatatt ataaaattat
    34861 cagaattttt tatacataaa tattcaagca aatacaataa aacgccttta attatcactc
    34921 caaatattaa aaaggcactt cttgaacgag aatatgaagg taatataagg gaattggaag
    34981 gtatgatgga aagggctgtt attgtggaat catttgactc gattttatta gaaaaggtta
    35041 gcaatgaata tacaaataat atagttgata aagataatag tgattttgaa tgcagtaatt
    35101 tagatttaaa aactttagaa aaaaaatata tctataaaat ttataacgaa aataatagaa
    35161 atactacaaa aacctgtgaa attctaaaga taactcgctc cactctatgg cgtaagttaa
    35221 aagaaataga agatgatgtt taaaaataat acatacctat atatatcaaa acgttttatg
    35281 tttaatttta atacataaga cgtttatttg ttttcaataa aaaatacaat tatatgataa
    35341 aaagaatctt tgtaagtgaa attctcgtca atcgtacttt taattataag taatctacag
    35401 catttcaatc gattattaaa aataatcatg ataactaaag atacaaactc tatatattgg
    35461 catattaatt gcttttataa tacctatata aaaatgaaag ggagtgatac tagatgcaca
    35521 tcttaaaatc agtgaaaaag ataccaggag gacttatggt ctgtcccttg ttattgggag
    35581 cactatttaa tacagtatgt ccacaagctc ttgaaattgg aggattcaca acatccttat
    35641 ttaaaactgg tgcaatgagt atacttgctc tattttgtct atgcaatgga gctcaaatca
    35701 atatcagaca agctggtaaa ccattgacta aaggtatagt acttacagca acaaaattta
    35761 taattggtgc agtattaggt attattgtta gtaaatttat tggacctaaa ggtataattg
    35821 gtattacacc tcttgccata gttgctacca tgactaattc aaatggaggt ctatttgctg
    35881 ctcttgcagg tgaatatgga gactccacag atgttggagc aatatctatc ttatctctaa
    35941 atgatggtcc tttttttaca atgcttgctt ttggagtaac tggacttgca aatgtaccta
    36001 taatagcact atttgcagca cttataccaa tactacttgg atttatactt ggtaaccttg
    36061 atgaagatat acgagaattt cttgcacctg gtacaacatt attaattcct ttcttcgctt
    36121 ttcctttagg agcagcatta aactttaatc aaattataac tgctggacta cctggagttg
    36181 tacttggttt aggagttact ataataacag gtatgggtgg gtactttgta atgaaactta
    36241 tacgtgcaga acatccagca gtaggtgcag ctacaggtac aacagccgga aatgcagctg
    36301 gtactcctga agctttagca gctatagacc ctactctagc tacaatagca gctgtttcaa
    36361 cagtacaggt tgctgctgct attattgtta cagcaatatg ttgtccaatg ttagtttcct
    36421 atctagataa aagagaaaaa aagaaaaaat ctatttttaa aacaaataaa aatattgaag
    36481 taaattaata cttaaggagg taaaattaat gaatgcaatt attcatgcaa atgaaaaaga
    36541 taatctagtt acatgtgtca gacctttagt taaaggtgaa aaagtttcaa ttgatggaaa
    36601 atcttacata gtaaatgata atataccagt ctttcataag atggctacag aagatgtaaa
    36661 aaaaggtgat gttgtataca aatacggtga aattatagga attgcaacag ttgacataaa
    36721 aactggtgac tatgttcatg tacataacat tgaaagtaca cgtggtcgtg gagataaaaa
    36781 ataggaggaa gttaaaatga aattaatggg ttatttaaga gaaaatggtc agtttggtat
    36841 tcgtaatcat gttttaatta ttccaacatc tgtatgttca agtgagacag ctacaagaat
    36901 agcatcactt gtgcctggag caatagcaat ccctcatcaa catggatgtt gtcaaattgg
    36961 ttctgatata gagcttacag caaagacatt aataggattt ggaaaaaatc ctaatgttgc
    37021 cgcagtttta gtagttggtc ttggatgtga tggtattcaa gcaaaagaat tagcatctga
    37081 aatagctaca acaggaaaaa aggtagatta cgttgttata caggaatgtg gcggaacatt
    37141 aaaaacagtt tctaagggag ctgaaatagt aagtaaaatg gctcgtgaag tatcaaaaga
    37201 agtaagagtt gaatttggta tgagtgaaat tacattagca cttgaatgtg gtggttctga
    37261 cccaacaagt ggaatagctt caaacccttc aataggcgtt gcatcaaacc ttcttgtaga
    37321 tgaaggtgga agtagcatac taagtgaaac tacagaagta attggtgcag aacatttgtt
    37381 ggctacccgt tttgaagatg aagaaatgaa agataagttt cttaaatttg taagtgatgt
    37441 agaaaaaaga gcaattgcta tgggagaaga tttacgtagt ggtcaaccta ctccaggcaa
    37501 taaaactggt ggactttcaa caattgaaga aaagtcactt gggtgtatgt ataaggcagg
    37561 caataagcca ttcaaaggtg ctcttgaata tgctgatatt gtacctcctg ataaaaaagg
    37621 attatatttt atggatactc caggtcaaga tatagattct atcactggta tggtagcagg
    37681 tggtgcacaa attgtaatct tttcaactgg tagaggtact ccaacaggaa gccctatttc
    37741 accagttatt aaaatcactg ggaatagtga tacatacaac aaaatgccag acaatatcga
    37801 tataaatgca ggtagaatta taacagatgg tgctaaaata gcagatatag gtcaagaaat
    37861 atttaatgaa ataatagaag tctgtaatgg taaacatacc aaagctgaaa gtcttggtca
    37921 tagagaattt ggcatttaca gaatttcatc tacattttag attgtaacaa aatatctttt
    37981 ataaatataa tacttatgta gatacataag ctaaaagttc tttctaatac tataaaaatt
    38041 ttctatactg aaaaggaact gtatcaaaat tattttgaaa acagttcttt ttttaacctc
    38101 ttttactcaa aatattataa aataagattt aaacaataaa cgtatcttga ttaatctcta
    38161 agaagacata aataaagcta aatgtaaagt gggataaata aaatttaata tctttgtatg
    38221 aaaagatatt tggtataata tgtctgagag aattcttatt tgtaaacaaa taaaggatgg
    38281 aggatgaaac aaaagaatga actttgaaaa cacaaaaaat aaaaaaataa tagctacttt
    38341 actattgaca cttcttttaa tcgtgtcatt aacatgtgtc acttttatta tgaatctaaa
    38401 taaagtaaca cataatgaaa cagaacgata tcttgtagaa gtttcacaag gtatttccac
    38461 tacaattaat gtgaaatgta aaagtatatt taggacacta tattctatgg gagatactta
    38521 ttttgagatt aatgatagtg aaaaagaagt caatagatac ttatcaaaaa aattaaaatt
    38581 atttgaattt gattggttag gtattataga ttctaatgga aattttgtaa gtgcccttaa
    38641 agatacaggt aatgttaaag gacaagactt ttatagaaaa gcccttcaag gcaaagaaac
    38701 aattactcct gttaaatcac aatctggtac atatggaatt ttatattctg taccactata
    38761 caatggcgat aaaattgttg gagctgttgc tgcttggaat actattgata ctatgagaaa
    38821 tttattaagt gtagaaagct ttcatggtga aggattttcc caaattatcg accaagatgg
    38881 aaattttatt gtaagttcag caaacaaaaa tgctccaaaa aatgtggtaa atttttttga
    38941 catgattaaa caccaaggaa aacaggttga taaaaataaa cttgaagaaa tgaaaataaa
    39001 cttaaaaaag aacaaaactg gttctatgta ttatacatta aatgatggta tttctaaggc
    39061 aatgcactat cttccattac aagaagaaaa cttatacctc ctttcaattg ttccaacaaa
    39121 aacagcaagt gcacagtttg atttacttct aaaaaaagca atcttcatca atattttaat
    39181 tgttatacta tttttattgc ttattatatt gattatgttt ataaatcaaa aaaacagggc
    39241 acaacttata aaaatcgcct atgtagactc tgtaactaaa ggttacagta aagcacgttt
    39301 tgatattgaa gctaaaaaaa ttatacagtc atcttcatca gaaagctatt cattggtatc
    39361 tataaatatt cagaaattca aacttattaa tgattctttt ggtagtgaag caggagataa
    39421 aacattaaag tacatacatg atgtcattag taattatcta gaaccaggag aattgctttg
    39481 tcgagtttct aatgaccagt ttaatgtact tattaaaact attcctcaaa aagaaattct
    39541 taagtacata gaaaatatca ccaatgatat taatagtttc aataaaaatg aagaatgtaa
    39601 atattttata gctctatcta taggtgtata taaaattgat gacccaaatc tacctttagt
    39661 ttcaattcaa gaccgtgcaa atgttgcacg aaaaaataat aaaggaaaca ttggaaatca
    39721 tccactttat acatgtgttt tttatagtga tttagagcgt ttaaaaatga ttaaagaaaa
    39781 agaaatggaa aatagaatgg aggaagcatt aaataataac gaatttatag tatatcttca
    39841 gcctaaaata agcctcaaag ataatactat tgtaggtgca gaagcattag taagatggca
    39901 agacccaaat aaaggcctta taccaccaga cgagtttatt cctttctttg aaaaaaatgg
    39961 ttttattaca aaactcgacc actatgtttt tgaaaaagta tgtagtatga taagaaaatg
    40021 gatagataat ggagaaactc caatacctgt ttcagttaat ttttcacgtg ctaatttaaa
    40081 taatatagat tttttagaaa aatacagaat gcttcgtaat aaatacaaca ttcctgctaa
    40141 gctcttagaa attgaattaa ctgaaacact tgtatttgaa aatctccaaa aattaattaa
    40201 tataatagac caaatccatg aagaaggttt tcaatgttca ctagatgact ttggaagtgg
    40261 atactcttca ctcaatatgt taaaagaaat aaaagttgac acattaaaac ttgaccgtgc
    40321 tttttttagc tcacctaatg cagataatat tgctgaaaat catgtaatag aatctatagt
    40381 taatttggca aaaaaattaa atatgaatag tatatcagaa ggtgttgaaa caatcttgca
    40441 aatggattat cttaaaaaaa ttaattgtga tatgatacaa ggatatgttt tttcaaaacc
    40501 tctacctcaa gaaatatttg agaaaatgac ttttggaaaa aaactagaag aaaccagtat
    40561 ggatagttcc gtttaaataa aataaaaaac ttgtctctat aaaataattt taatcatttt
    40621 ataaagacaa gtctttttat tttccaattt aattttattt tctaaatttc ttacactcgg
    40681 cttgttttaa attccctttt taagaataat aatacgatta tcatagcaat aaaatctgca
    40741 actggctgtg ccaaccaaac accatctaaa ttaaattgaa ttggaagtac aatgattaat
    40801 ggtataaata aaataaattg tcttaaaaga gttaaaaaca ttgaatgttt aactttactt
    40861 atacactgaa aatacacagg tcctacaata gaaatcccca ttataggcaa tgtaattaga
    40921 tttaggctta tacctcttac tgctatatcc atcaaatctg aatctttatt aaatatacct
    40981 acaaatactt ctgggaaaac ttgtactact aaaaatccaa atgacaatat gacaactgac
    41041 actatgatag ataatattaa agttttcttt gcacgctcat attgttttgc accataattg
    41101 tatgatatta tagtttgcat accttgattc aatccaaaca caggcatcat aaacatcaat
    41161 aaaatagatg taagtgctgt catagctcca atagctaaat ctccaccata aacctttaga
    41221 gaattatttg taaacatgtg agttatactt atagctactt ccatagcaaa aggtgtcatt
    41281 cctattgcaa ataccttctt tactatatct ttattcaatt ttaagttaca tttttttagt
    41341 tttaaattgg acttccctct tataaaataa tgtattaccc aaaaaaatac tactatttga
    41401 cagagtactg ttgctatagc tgctcctttt atacctaaat taaatacaaa tataaatata
    41461 gggtccaata tcaggtttaa tacacatcct acaatcattg tccttgctgc taattttgga
    41521 ttaccttctg ccctaattgc attattaaga gaaaatgcaa ctaaattaaa tatacttcca
    41581 accaatatga cactcatata gtcttttgca taaaatattg aatctttact tgcacccaaa
    41641 ataaaaagta tctcttctaa gaaaactaat cctaatatag ttataattaa agagataatt
    41701 atagataatg tcaaagcatt acctaatatc ttctctgctt cttctctatt tctttcccct
    41761 aactttatag acaatcttgt gctagcacct actgatacca acattccaaa agctattatt
    41821 agagtaaata ctggcatagt tacaccaaga cctgcaatag ctatagagcc aataccttcc
    41881 atagaaccaa taaaagctct atctactaca ttataaagtg aagttaccat cattgctatt
    41941 attgcaggta tcgaatacct aaataataaa atccatattt tttcatgtct taatgcttct
    42001 tgattctcca tgttgtcacc atttacacca tgtcataagt tatacaaatt ggtttatttg
    42061 ttcttgggtc tgttgctatt tctgcatcaa tattaaataa ttcttttaga ttatccttcg
    42121 tcataacatc atatgcatca ccttcacaaa ctattttacc tttcttaata cctatcatgt
    42181 ggtcagcaaa tcttgctgca ttattaagtt catgtattac catgacaata gttcttcctt
    42241 gttttttatt tagttcatct aataatttta gtatctccaa ttgatgtgcc aaatctaaat
    42301 atgttgtagg ttcatccagt aataatatat cagtttcttg tgccaaagcc atagctatcc
    42361 atgccctttg tctttgtcct cctgataaat cttccatatt tctatcctta aattctgcaa
    42421 ttccagtaac ttctaaactc caatttacaa tctctctgtc ttctttacta gaattaccaa
    42481 atccactttt atgaggaaat cttccataag aaattaattc tgaaacggta agaccactag
    42541 gagcttgagg gctttgtgga agtacagcca tatcttttgc tatttcttta gacttctttt
    42601 tgtagatgtc ctctccattt atatatattt tcccactatt agggctaata attctaccta
    42661 tagttttaag tattgtcgat tttccacaac cattagcccc tatgatggta gttatttttc
    42721 cttttggtat atttaaattt aaatttttta taatatctgt gtttccatat gatacattta
    42781 gattcttagt atttatacag ttcataacaa caccctttcc taatcattta ccaacattaa
    42841 ataaataaag tacggcactc ctattataga aactactata cctactggta tttctatagg
    42901 tgctagaaga tttcttgata tagtatctgc tattaaaagt aataatgttc ctatcaatgc
    42961 tgatactggt attaatcttt tatgctttgg tcctattatt tttctaccta tatgtggagc
    43021 tattaaacct aaaaatgaaa tactacctgc tactgctgtc gatacaccag ataaaattac
    43081 tgcatatatt ataagtcttc ttctttgttt ttctacatct acaccaagac ttatagatac
    43141 ttcatcaccc aaatttaaaa catctatata tttagattta taaatagtta tacccataaa
    43201 aatcactata aatggaagca cagctattac atatttccaa cttgttcccc aaatgcttcc
    43261 tgatgtccat gccataaccc tattaaattc ttgtgttgta aatttcaatt ggaatatcgt
    43321 caaaattgaa gtaaaagcta tgtttacacc tataccaata agtagtaatc ttgacgaatt
    43381 tataccacct ttccatgcaa gagaatatat aagaaatgct ccaaataaag ctcctataag
    43441 tgcaacaata ggcattgtaa atacagtcaa gttactcata ccttcatata cattaccatt
    43501 cataaggtat atataaacta ctacaaacaa tgcagcacct gaatttattc ccaaaattcc
    43561 agaatcagct aaatcattct ttgtaactcc ttgaagtatt acacctgctg ttgataatgc
    43621 agaaccaacc aaaagtgcta ttactattct tggtaatctt aatttaaata ttgcaatttc
    43681 atgattacgc tgaccctgcc ctaaaaaagt ctttataaca tccattggtt ctatagaaaa
    43741 tgagcccata tttaaactca ataaaaaagt gataaaaata agcaccatta aaattgatat
    43801 aacaagtaat gttttagaat ttatttttat aatatttttc atagtaccta tttctccccc
    43861 tttctaacaa ggtatataaa tattggcact cctataagtg ctgttataga acctactggt
    43921 gtctcatatg gaggatttat catcctactt aatatatctg tatatacaag caatacagct
    43981 cctaatacta aagagctcgg tattatatac ttataatctg aacctactat tcctttagct
    44041 atttgaggaa ctataagacc tataaaaata atattaccag acactgacac agatgctcca
    44101 gtcattaata ttacaagtac tatacatata aatctaacaa acttagtttt ttgtcctaat
    44161 cctattgcca cttcttctcc aagacttaat atagttattc ttggagccat aataatagct
    44221 aaaataaatc caataccacc agctacaaat agcaatttta taccttccca cttcactcct
    44281 acaagccctc ctgatatcca gaaacttaat tgttgagata ggttaaaata catagatatt
    44341 gctgatgcca aagaaattag caatgtacca agagcgactc ctgcaagagc taattttaca
    44401 ttattaactc ttcctcttga tttagaactt ataaaatata taaataatcc acttatactt
    44461 gctccaataa atgcaaacat cattacacta aaacttccat gtataagttg aggaagtttt
    44521 ttttgaagta ccagtgatat cgaaattgcg aatgtagctc cttgtgtaat tcctataaca
    44581 gatggttcag ctataggatt tctcgttatt ccttgcatta ttgccccaga aactgctaaa
    44641 aaccctccaa caagtgcagc tgctattgcc cttggaagtc taacatcctt tactattctc
    44701 atatttattc catcttccat ttttatcaaa ctatctataa cagttgatag attcatatct
    44761 tttgccccaa tagttatgga taatacaatt ccaaatacaa gtacaactat acttactaat
    44821 atcaacaaat aagttatatt ttttttactc agcttagtca attatcctac ctccttttcc
    44881 cttttaatcg tcagtataat atcatctatt aagtatttta attttaagat ttattaaaaa
    44941 taggtgtgaa aaatgaatat cattatctca cacctactaa gttaagaatt actttgttaa
    45001 ttcattttta actgattcta ataataactc ttttccaatt ggattgtatg attgactgaa
    45061 aaatggagca gcatcaagta ttgttacatt accatctttt actgctctta tttgagccca
    45121 gatagcacta ttttctaaat cttttttatc tgcttctgta gcaattacaa ctatatggtc
    45181 tgcatctata tctgttaaac cttccatact taccattggt agtgttattc catcctgttt
    45241 tggcatattc ttaggtctag ctaatttcat atcatcattg attagagtac ctattccacc
    45301 atcactaaat accataaatt gacctgaact tgccaacact ggtaaataag ttttttctcc
    45361 attcttttct ataacttcct tacctaactt tgtagctttt tcatcatact tctgtagcca
    45421 acttttatct tcttcttctt tgtcaaataa ctttgaaaca tcagttaact tgcttctcca
    45481 gtcatttgca taatctttca tcataactac aggagctatt tcttttaatt ggtcatatat
    45541 tttttcttgt ctttgactca ttattattaa atcaggattt acttctaata tagcttccat
    45601 atccatagta tccatcattg agtgcccaac tatctttaca cctttaagct cttctcttat
    45661 gtaacttggt aatttatcag tttcatatga gtctacattt gctgttgcaa caggcttata
    45721 acctgctaat aatagttctt cactacttcc tgatatatca actatttttt taggatttga
    45781 tggtatctta acctctcctt taacagattg tacaactctt gtctctgatt tatctttatc
    45841 ctctgtattc ttatctgaac atgctgtaac aagtactaac gtagttataa tagatataaa
    45901 tattgcaagt gattttattt ttttcatgat tacttctcct acttgtttat tatacttaca
    45961 tgatattgat tatcataagc acatatttat tatagcattt ttctattttt agtcaatatt
    46021 attttgtaaa aggataaaaa ttcctaatta atcttaatta tatatagctt agataaggtt
    46081 ttcttatatt aaacagtatt ttttttaaga attggacaca aatacaatga cttttcagtt
    46141 aaacaatgat aaaatgcaat ttatagataa ggaatttagt agggaggatt caaaacatgg
    46201 tacatttagt atattgtgat aatgcaggaa aaaaaggaga aaaggtctta gataaaatct
    46261 tggatggaac aaaaacaatg gttattagag gtgctgctgg tagaaaaata ccacatagta
    46321 gagtatttga agatgagtta ctttatttta tggaaaaagg aactgcaaaa atatctgcaa
    46381 aagccactgt taaaaaggta gaaaactatg ttaaattaac agaagatgaa atttctaaaa
    46441 ttttaaatga aaatcaacca aaattaaatt tatctgaaaa gcaaaaagtt cgttggcata
    46501 aaaaatgttt atgcttagtt gaatttgaaa atgttgaaga aataacacct cttgattttg
    46561 accatcaagg aaatatggat gattggctta ttgttgaaaa aattgaagat gtagttgttg
    46621 gtactagtat accttacaat tatgagaagt ctaaattcta aagtatcaat aacataatac
    46681 tatattgcta aactctactt aaataaaaaa agagtgcatt taataattat aaaaattatt
    46741 tttatacact cttttttaat aataatttta aattacttac tttctaatct ttcatataca
    46801 tctataaatt cttctgctaa ttgttgaaaa ttcatagctg tcattaaatg gtcttgtgca
    46861 tgaataagta taacacttat ttcagtttta ttaccattag cttcattttg tatcaattct
    46921 gtttggaatt tatgagcttt atgaattgat tctttcgact tttcaataca ttctctagct
    46981 ttatctatat tcccgctctt tgcttctttt attgcttcaa atgctagccc tttcgcatca
    47041 cctgcaaatc caattattcc aaaagatatc tctatcatct tctcatccat ttattcgacc
    47101 tcctaaatat ctctatagct tgatatgact aatccattct tttctaaaaa ttctttgact
    47161 tttttagatg taagtatctt gtgctctttc gttctatcaa tagcataaga tgtagaattt
    47221 aaaatataat catctaaaaa agctgggtga gacataatat ccactacatc atacttcatt
    47281 atttcgtcta tattttttat aaaatattct tcacttacat tttccttata aaaactatct
    47341 attaaaggaa ctactttaga atactctaaa ttatattcaa atccacctct tattggaaga
    47401 ttatacttgg ttacaatctt ctctattact ggctttaaac ttactaaagt atggatatga
    47461 tggtgactat ctaaatgaga tatatctatt ccaagccctt ttaccctatc tatttgagca
    47521 caaagttctc tataaatctc atcacaatcc attttttcaa taatttcgtc tgtaatcctc
    47581 ctaataaaaa aaccgtcttt atcaacaata gtttttaagt tagataataa tggtctacca
    47641 caacttaaag tcatatgaac tccacaattt aaagttttat tttctttaag taagcctact
    47701 ccatgttcta ccccaggcat atttgccatc atagaagtag acctaactat accattatta
    47761 tgagctgaaa ttattccata gttcacagct tcacaatatc caaaatcatc tgcatttatt
    47821 ataattttag tcataccata acctactttc tatagacaac tatctattaa atctaggaag
    47881 ataatcttta tgagcttcca acatttcgtc taatatagtt tttgctaagt catcagatgg
    47941 aatcaatggg tttatacaaa gtgccaaaag agcagattca taatcgccat atacagctgc
    48001 tttagctgcc aatacttcaa atgatttgat ttgacttact aatccatgca cagaatctgg
    48061 taaatatcct atacttattg gttttggacc attttttgtt attacactac ttacttctac
    48121 tgcttgttca tctttaaaat ctcttataga acccttattt aatgtattaa ctacttggat
    48181 atcttttttg tcattgtata tagaacttat taaattacaa gcagcatcac tatagtaagc
    48241 ccctcctctt ttttcaagtt gaggtggttt tacatctaat ttttcatcct tatataattc
    48301 aaataattgt tcttccaatt ctttaactac ttgacctcta gcttttccct ctttaaactc
    48361 tctcaactca tcctcaagca tttctttagt tttatagtag tatctatggt atggacaagg
    48421 tattgcaccc aaagatttta caaattcagc attaaaatca attgccttta tattttgcat
    48481 acttatatct gctttgacaa atttatcaat tgcttctttt gtaacatctt ctccatctaa
    48541 agatacattt agaccataaa ccatatgatt aagacctgca aaatccatac ttattctgtc
    48601 actttctaca ttaaatagtt tggcaacatc attttttaaa tgaattggca cgttgcatag
    48661 acctatatat cttctaaaat tagtatattt gaatacagcc tctgttatta ttcctgttgg
    48721 atttgtaaaa ttcaccatcc atgcatttgg acataattct tccacatctt ttattatatc
    48781 aaatataact ggtattgtgc gaagggcttt aaataaacct ccagcaccat tagtttcctg
    48841 ccccataact ccatgagata aaggaatagt ttcatctttt attctcgcat ctaaaagacc
    48901 tactctaagt tgtgttgtca caaagtctgc atctcttaga gcttctcttc tatctaaagt
    48961 aagatttatt ttcatatcta ctccagcttt ttttaccatc ctcttagcta gatttccaac
    49021 tatctctaat ttttcttttc cagcttctat atctacaagc cataattcct ttacaggtaa
    49081 ctcttcatat ctatttataa aaccctctac aagctcagga gtataacttg aacctcctcc
    49141 aattgtaact atttttagtc cctttttcat ctcattatac catccttacc tataatttaa
    49201 tatactctac aaaaccccat acatttattt aaaactctat acatttattt accgaaataa
    49261 aactacctag ttgttaattt tcaatttatt agcttccatt ttttcagacg ctatgacaaa
    49321 tggaatatat attaatattg ataatattaa attaaatagt gctaaagctc cgccagtcca
    49381 gtcacctgta gccattgctc cacctaatat aggaggtgtt acccaaggta ttttaggtaa
    49441 aattactggt gctactaatc caaaatctat tgctaagtat gatacagcac tacatattac
    49501 tggtgcaagt acaaatggaa tcataaatat aggatttaaa actattggaa gtccaaatat
    49561 caatggttct cctatgttaa atattgcagg tggaccacct aatactatca tctctttacg
    49621 tcttcttcca gctattaata aagctactat taatcccaat accattccag aaccacctaa
    49681 atatacaaat gcatcaaaga atgcacctgc aagtacatgg tatccttccg ttgctcctgc
    49741 ttgagccaag gcagcatttt ctccacctaa tttcataagt atagtttctg taaaaggaag
    49801 tgctatattt gcaccatgaa gtccaacagt ccaaagtata tgaattataa atgcaataag
    49861 cattgtagaa cctagactat cagctacatt tgatagtggt gctcctaaat aagtatttaa
    49921 aatatctgtt aagaaacttc cattagaaag catttttata aatattccta ttacagtaaa
    49981 tatcattata gttaacattc ctggtattaa ctttgcaaat gatcttgaaa ctgctggtgg
    50041 aactccatct ggcattttta tagttaattt ctttacctta gataatctta caaatatctc
    50101 agttgataat aatcctatta atatagaaga gaataaagct gctgtaccta agtaggtttg
    50161 ttgtatcatt ccccatcctt caactactgt agttcctccc tcaggaacta ttttaccaat
    50221 ttgtggagcc attataaaaa agatagataa agctataagc ccagattgta acccatcact
    50281 ctcataagat tttgctagaa aataagcaac acctattact aagaatactg ccattgtacc
    50341 tattgctccc caccaaaggt cgcctccaaa tgtggtccag ttttctccaa atatacttgc
    50401 catcaaattt ttgtatgctt ccaatggtaa gttatttatc aatgttccca atgcacctac
    50461 catagttata ggtatcatta ctataaatgc atctcttact gctactaagt gcctttgagc
    50521 tcctatttta gcagctacag gcactatata tttatccata aatgacatga atttttccat
    50581 tttacatcct ccagtacaac tttattttga actatttaac tctacagctc tatctaacac
    50641 agcttttcca ttacatcttc cataatccat catatttata acttctactg gaatattata
    50701 tggttttgcc atttcagttg cttttcctaa tacatatcta acttgaggcc ctaaaagtaa
    50761 gacatcacaa ttttctattt cattttttaa gttcacttct gatatagccc atatttttgc
    50821 ttctataccg ttttcctttg ctgcatcctc catttttgta actaataaac tagttgacat
    50881 tcctgctgaa caagctaaca ttatttttat cattttttcc cctccaaatt agattcatta
    50941 aatatttttt aagtcataag ttttttaaac tatacattta aaatatgttt ttctattaat
    51001 tttttcttaa tgtatatatc ttatttttaa atgtatatac atttaattct tgatattatt
    51061 atataccaaa tgtatataca tttcaagaaa actttttcat tttatttaaa ttttattcga
    51121 caacagcatt caaagttaat gtatatccat agtgatatgt gtgtgagtac tcaaaaatct
    51181 cactattttg taacttacaa atttggctta tatataaaag tggctctggt tcttctaatt
    51241 ttagattatc catacactct tcattcgata ttacagcttg tacttctctc tctgacatgg
    51301 ctatcttgta ttcacacact tcttcaacaa aattataaag agaattttca caatgagtct
    51361 tatttaaatt tggaaataac ttaactggca tataagtaat catatatgaa actcttgcat
    51421 cattggctaa tcttactctt tttatttccc aaacattttc ttctaaactt atattcaact
    51481 tacttgataa attttcatct gcctgaacta tttcaagaga taccaatata ttagatactt
    51541 tatagccttt actttccatc tctttagtaa atccacttac agacgatata ttatcatata
    51601 tattatttgc aataactata ctacctacac ctctttgtct agttatatag ccttctttaa
    51661 ctagattatt aagtgcagac cttacagtca ttctagttac attaaattct tcactcagct
    51721 gtttttcaga agggattaaa tccccttctt tcaaactgtc tgaatttatt aactctctaa
    51781 catgattttc tataacttta taaattggct ctttcattta attcactcct tattaaatct
    51841 tttatataat aagataattt tatatacaaa caaagaaaat gtctatacat ttaagataat
    51901 ttaaatttta ttcagaaatc ttgtacaact ttccgagttt taataaagat ataaatagac
    51961 ttatcattaa tatacctttt aatatacttg ataaggttat actccaccat acaccattta
    52021 gacccaacat ttctggtcta gatataaagt aagccaatgg tactcttgca ccagtcagta
    52081 tagtaattat aatagaaggt atataggttc tccctaatcc tttgaaagct cctgttgtta
    52141 ttatttctaa acacataaaa aattgagaat agcctaatat tttaagataa actgctcctt
    52201 tttctattgc ctcactttca tctataaaaa tagaaaatat actctctcct gcaaacacta
    52261 atactaaagt agttattata ccaagtacag aagatacagt tatagctatt ttgcaacctt
    52321 tatttattct agaatacttc ttggcaccat aattttgtcc aacaaaactg cctaatgcaa
    52381 ctgatagccc ttcagccgtc atccaggaaa ttgcttctat ttgtgagcct actttttgta
    52441 ctgcaacagc cacaggcccc catgatgcta ctattactcc taatagcatt gagaatactg
    52501 taaacatacc actttgtatt gctataggta atcccaattt atacagaact ttataatatt
    52561 tagtctctat ttctttaaat agtcttaatt taaaatattc ttctttactt ttaactatta
    52621 tatatataaa acatgtagta actactatct gagcaaatac agttgcaata gcagctcctg
    52681 caacaccaag ttttggagca aatccccatc caaaaattaa tatagggtca agtataatat
    52741 tagttattaa tcctactgta ttaatacgaa aaggagtttt actatttcca agaccattga
    52801 aaattgcagt aaatactgga ttaataaaat aaaataccat acctagagct actattatca
    52861 aatactgtct agacatggtt ataacttcta agtctcctaa tctaaaaaaa cctatcaatt
    52921 gtttattaag tactattaaa gaaattgtat atattattgc tagtataata tttatttcta
    52981 ttgctgactt catatatgat ttagtagtgc ttatattatt tgcaccaata ctttgtgcta
    53041 cttttatctc tccacctact tttgaaatca taataaatgc cattgcaagc catggaaaaa
    53101 aaccagctgt tccaactgca gctactgctt tacttccggc tttaccaacc catatcatat
    53161 ctatcatgtt ataccccatc tgtataaatg aagtccccat tattggaagt gatagcttaa
    53221 gtaatttttc tgtaattctt ccttctgtta aattaagtct gtctttcatt ttccacctct
    53281 tttatattaa atttatttgc ttatatagct agattaatca ttttatttga ttgagttcac
    53341 tatccttcaa tttatattat catatctcag gattgcatct caatcatact tatgtttaag
    53401 atacagtatt ttacctatct atgataaaat taatacttat gaatataaat ctagccattt
    53461 catcaataca tattctaacc cttaacttaa cttcaattaa gtatacatat cgtaaccaat
    53521 tagaatattt tatacggtat cttccattaa taaacaacca atatcaatga tttatatata
    53581 attttattta tacataaaat agtatactat aataataaaa aaactatatt tgaatgcttt
    53641 aagcatgttt actaattgta atttccacac aaatttgata atatatgaat atattatggt
    53701 gaaatttata gatatatatt aattatgggg agattgtggg aggttctttt cacaagacat
    53761 ttaagctatg aaaataaata aaaaattcaa tagagttgat atgcaggttt caatacttac
    53821 tgcaattatt gtaataatat cttcctcatg tgtatatttt tttaattata cactaactta
    53881 taagagcatg atatactctt taagtgagag gtcaaaacat atctatgaat atgtagaaag
    53941 aaatattgat aaaaatacct ttactgaaat taattctaaa gaagaccaat caaaaaagtc
    54001 ttataaaagt tctaaaatcc ttttagaatc tgtaaaaaat actactggag tcatgtatct
    54061 atatactgct aaaaaaacaa aagatggatc actagtatat gttgttgatg gtttaaattc
    54121 atctaggagt gattttagaa atgctggtga tttgatagaa aaagagattt ggggagacct
    54181 taacaaagca ttagataatc atatattgtt acctaaaaag attaaatcaa catcttgggg
    54241 atacatattt atatcgtatt ttcctattca caatgatgtt ggtaaggttg ttggagtaat
    54301 aggaattgaa tttgaagcaa aacatcaata caatacattt aaatttataa gtatagttac
    54361 accaataata gcattattaa cttgtctaat atcagcattg attgcagtga ttctatttaa
    54421 aagaatatct aatcctacat atactgattt tgctaataca gattatttaa caggcctaaa
    54481 aaatagaaat gcttttgaaa tagatatgaa taacttaaac aattcaaatc taaagaatct
    54541 aatatctatc atatcaatag atttagacgg tttaaaaaag attaatgata aatttggcca
    54601 tcagacagga gacttatata ttaagcaagc aagtaaaatt atacaatatg taataaataa
    54661 aaaatatata gtttatcgta ttggaggtga tgaatacata attattctaa aaaatttatc
    54721 tcacaaagaa ataaataata ttataaataa tattaattta aaaatagttg aagaaaactc
    54781 aactaatgaa ttaaaattat caatgtctat tggatatgct atttttgatg aaaaagtaga
    54841 tgtttcttta tttgatacat atcgtcgtgc agattctcaa atgtatgata acaaaaggaa
    54901 aattaataaa caatatcaat aataaattta aaaagtctat tctttaaata ataaatcaca
    54961 agaatagact tttttaaatt tgtgttttta taagataaat tatttaatta aagtttgttc
    55021 ttttttctaa acgattcttt ataaattcat atattacttt cactaatata tttgtgacta
    55081 atattaacac agctagtgct gctgcctgtg cagtactccc cttatcatct agttgtacaa
    55141 ttgatattgc agctactttt gaacttgcag tatatataaa aactaatgct gatattgtca
    55201 ccatggagtt taggaaaaag tacataaagt tctctaaaac tgctggcaaa caaagtggta
    55261 tagttacgtt cttaagaatt gatgcgctgt ttattcccat tgatttagct accatatcta
    55321 attctttatc tactttctta atagcagtag tagctgttat aaatgctact gaaaagaaat
    55381 gaactatatt acatataacc attataagta atgttccata taatccatta aacaaattct
    55441 taatgtatat tgtatccata aaattaaact ctaatttatt aaaaaataat acataagcta
    55501 tacctaaaac taatcctggc aatgccatag gcaatgtact taaaaaatac ccaaatgatt
    55561 ttaaatatgg agctttttct gttttttcat tcaaatatgc aaataagaaa acaaagctcg
    55621 tccctagaat agctgtaaat agtgacattt ttattgaatt tataaatggt ttaatcccat
    55681 caatactgtt tttcatagaa aaatgttcca gtgtcagtct taaatcatat ggccaaactg
    55741 atattaatga agataagatt acagttaaca ttacagctat tataccaaat gcaataattc
    55801 ctacaacccc tcctaaaata ctatctctta acttattagt tttaacctta tatggaattg
    55861 actttgaagt tatatatgaa ttttgatttt tttcaatttt tttagttact ataaacgata
    55921 ttattgcagg tattaaaagt aatattgata cagttgctcc cattggcata ttctgttgcc
    55981 ctataatttg cttatataca tctattgata atacattaaa ctctcctcct atcacctttg
    56041 gagctccaaa atctgtaaaa cataatgtaa acgatacgaa tgcagaactt attaaagagt
    56101 attttatact tgggattgtt atgcttataa attctcttat cttgcttatc cccatagtat
    56161 tactagcttc atatagtcta taatcggttg aacttagaga tatataaagt atttgaaatg
    56221 attgaggaaa tacatatata atttgtgcca atattattcc cactgctcca tatattggaa
    56281 catgcactcc aagtaaatta gttaccaaac cttgatttcc aaataaatat actagaccta
    56341 ttgcatgcat cattgttgga gcaaacatag gaaacatagc taatgattta aaaaaacctt
    56401 taaatttaat ctttgttcta gttaatgcat atgcatatac taatgcaagt gttagtgata
    56461 ttacagttga tataactgat acaaatactg tattttttag agaatttaat agagattcag
    56521 aagccaagta ttcttgaaag ttttgtaatc ctacaaagac tccatcttta tctaaaaaag
    56581 cctgtacaaa tagatatatt ataggtgcta ataaaaatat tactaaagac ataactaata
    56641 ctgtaagcat acattttttt atatctaaat tcatttttga tttaagactt atacttttag
    56701 aacttatagc attattattc atacacttat gctcctttaa cttttggata ctttaaatag
    56761 tatttttcgt ctatacttat ttttacaagg tcaccttcta ctaaatttaa attaacccac
    56821 tcttttatag aaacatcact tattatgaaa ttttcattta atttatcttt tatttcaact
    56881 ctcaataaat tccctctaaa ctctatattt gatattatcc cttggtagtt ttcttttgtc
    56941 gatttctcta tttgaacata ttctggtctt acagttaata tagaatctcc attatcaaaa
    57001 cagtttgtat ctcctataaa ttgagctgta aataggtttt gaggattttg gtatatttct
    57061 tctggagtcc ctatttgcat tatatctcct ccatttagaa tagctatttt atctgccata
    57121 gttatagctt cttcttggtc atgtgttacc attattgtcg ttatattaag ttctttttgt
    57181 aatcttttaa tgtccattct aagcttgtgt ctaacctttg catctaatgc agacattggt
    57241 tcatctaaaa gtaaaaactt tggttcaaga gctaatgctc ttgctattgc aatcctctgt
    57301 tgttgtccac ctgataatgc tttagggtat ttatgagctt cattagtcaa tccaactgtt
    57361 tcaagtactt ccttaacttt attatctatt ttttcttttg aaacttttct ctcttttagt
    57421 ggaaaagcta tattgttata agcagtcata ttcggaaata atgcatatga ttgaaatact
    57481 ataccaaaac ctctctttga tggctctaaa tttgtaatat ctttatcctg gagaattata
    57541 gttccactat ttacatcttc aagacctgct attattctaa gtaatgtagt tttaccacat
    57601 ccactaggtc cgagtaaaca tagaaattcc ccttcttcaa tatccaaact aatattattt
    57661 aaaacctttt tttggtcata acttttaaac acattattta tttttaagta actcatatct
    57721 tatctctcct tatatagtta tttttttatt ttaaatttta tatcctactt tttcttctaa
    57781 aattctttca tctaaattat taatttaaac tttacttact ttcagatttt gaaccgtatt
    57841 ttgattccca agttttaagt actgtacttc tgtttttggc agcagagttt aaatcaactt
    57901 cttttataag ctgttcaaat ggttgtttag aataaccttt tggaactgga ttatctgtct
    57961 ttatggaagt aactgctact tcatgtgcat atctatccat agctgaatca cttattgccc
    58021 aatctaaaaa tagctttgct tcttttttta tattatcttt tttaactaag gcatttgctt
    58081 ctaagtccca acctgaacct tcctttggaa atacaacctc tataggttct ccactagata
    58141 attgttgtgt agctctatat ccaagtgtaa tacctattgg atactctcca gagccagcta
    58201 acttcgcagg ttttgaaccc gagtgtgtat atgtggctat atttttatgt aatttatcca
    58261 tgtaattgta agcatctttt tcacccatca tttgaataag ccctgatact gtaagatacc
    58321 ccgttccaga tgatgctgga tttggcattg ttataagtcc tttatattct ggttttatta
    58381 aatcttcata actttttgga atatctatac ctagtttctt aagttcctta taattaacta
    58441 ctattgctgt ctctgggaca ctcattccta cccaagatac atcatcttca gtatctttaa
    58501 attttttatc aactttatca taatttttag gcttatatgc ttcaagtgca ccatcttttt
    58561 ttagctctat catgttcatt gctgataatc cccatataat atctgcttgt ggattatctt
    58621 tttctgctaa tagttttgaa gctattacac catgagaatc cataactatc tctacatcta
    58681 tattgggata ctcttctcta aaaccttcca tataataagc tatctgctct tcctctagtg
    58741 ctgcatatat tgtaagttta ttatttcctt ttccttgagt agtttgtggt gttgttgata
    58801 tgcaacttgt cataaatgta atcactacaa tgcacagaca agtaaatata aattctttca
    58861 tatcttcccc ctttgtgttt tttccttttt ttatttgttt tttattgttt ttgcttatgt
    58921 ttatataata cacctaattt gttaatataa agttaagtgt aaattaacag ttcgttaatt
    58981 tttagaaatt tttgttaaat atattatttt tagttaaata cagtctgttt ttaaacaata
    59041 tattaatttt tatagtatct acattttaat ttaaacataa aaaataagtc taacctctat
    59101 aaagtagaat gttagactta tttttataag tatttaatta tacaaccaaa tcattttttt
    59161 tcttttcttc aagtgctttt ttaagcacca tatccttaac cttcataagt ctagtagtac
    59221 ttgctctctc attttcttca agcttcatag ctatatactt aatagtctca atgtaatttg
    59281 gtatcattac attttcaaga gcattaacac gtctacgtgt cttttctatc tcttgtgcaa
    59341 gaagctgtgc acttttttca ctttctgcaa gtcttaaaag tggttgcata gcatctgaga
    59401 aagcttccat agcagaatct aattcacctg atgtaaaagc aagaccataa ggataaatat
    59461 cactttgatt gttttcagtt ttaaagtcaa acacaggaac atcaacactc attatatttc
    59521 tcgtagaaac atctactgaa actgattgct ttggcatcat aagtgctgaa cccagatact
    59581 cctgactcat aactgctctt gcgattataa agtttttata agcagtatca agagcatttt
    59641 ctgcttcttc acgcaatcgc ttattttctc ttacaatctc aagaaattgt ttcataagtt
    59701 catcaagttt atctttaaga agcttatgac ctcttgtagc agttttaagg agtttcttaa
    59761 gtctagtcat ttccatacgt gttggattta tatttaatct agccacagat atcactcctt
    59821 aggcatatat ttttcaaaat attcatcacg gatacgttta agttcacttt ttggtaacat
    59881 actaagaagc ttccatccga tttctaatgt ctgctcaata gttctatcag ttctaaatcc
    59941 ttgtgaaaca tattctttct caaattcatc tgcaaactta gcatacatta aatcaatctc
    60001 agaaagtgca gattcaccaa gtatagccat aagttctttt gcatccttac ctcttgaata
    60061 agctgcaaaa agctggttca ttgtatctgc atggtcttca cgagtcttac ctttaccaat
    60121 acctttatct tttagacgag aaagtgatgg taaaacatct ataggaggct gtatatcttt
    60181 tttataaagt tcacggctaa gtataatttg cccttctgta atgtatcctg taaggtcagg
    60241 aattggatgt gtcttatcat cctcaggcat tgtaagtatt ggaatcatag ttatagaccc
    60301 ttcatgccct ttcatttttc ctgctctttc atacatagta gcaaggtcag tataaagata
    60361 tcctggatat ccacgacgtc ctggaacttc ttttttagct gctgaaactt cacgcaatgc
    60421 ctctgcatag tttgtaatat ccgttattat aacaagtaca tgcatatctt gctcgaaagc
    60481 aaggtattct gctgctgtaa gtgccattct aggtgtagat acacgctcta cagctgggtc
    60541 atttgcaagg tttacaaaca ctacagaacg gtcgattgca ccagttgctt taaaatcgct
    60601 tataaaaaat tcagcatctt caaaagttat accaactgca gcaaatacaa cggcgaactt
    60661 agaatcagtt ccacgtactt ttgcctgtct tgcaatctga actgcaagat tggcatgtgg
    60721 caaaccagac cctgagaata taggaagttt ttgccctcta accaatgtat taagtccatc
    60781 tatagcagag actccagttt gtataaactc ggccggataa tcacgtgctg ctggatttat
    60841 tggagctcca tttatatcaa gtcttttatc tggtataatt tctggacctc catcaatagg
    60901 tctacccatt ccactaaaaa cacgacctaa tatatctggt gaaactccaa agtcaagact
    60961 ctttcctaaa aaacgaactt tactttcagc aaggtttata cctgttgagc tttcgaaaag
    61021 ctgaacaagt gcagtatctc catttacctc tagaactttg caacgacgaa tttctccatt
    61081 tgaaagttca atttctccaa gttcatcaaa ttttacacct tctacgccgt ttattaacat
    61141 aagaggaccg gctacctctt gtattgactt atattccttt atcatagttc ttcagccccc
    61201 ctctttttaa taaggtctgc aagctcgttg tctatttcat cttcaattga atcgtaagct
    61261 gcatctatat cgccttcttc tacatactta gcacgaccaa tcttttcaag aactgaaagc
    61321 ttgataatat cgtttatagt aacattttgc ttgatagcat cttgtgctga cttatagaat
    61381 tttaatataa gtcccatcat tctatattgt ttatgaagtg atgtataagt atcaacttca
    61441 tggaaagagt tttgatgaag gaagtcttct cttatagaac gagtaacctc tagtatcaat
    61501 ctatctccat ctgaaagtga atcaacccca accaattgaa ctatttcttg aagttcagat
    61561 tcaacttgta aaagtttcat agcttgagct ctttgagctg agaaattatc atttacattt
    61621 ttatctgccc atacatcaac tttttcctga tagagtgaat aactagtcaa ccagttaatt
    61681 gctgggaaat gacgtttata tgctaaagat gcatcaagac cccagaatac ttttactata
    61741 cgaagcgttg cttggctgac aggttctgat gtatcaccac caggaggaga aactgcacca
    61801 attgctgtaa gtgttccttc tctttcatcc atacctagac aatttacctt tcctgctctc
    61861 tcatagaatt gagcaagacg tgaacctaag tatgcaggat aaccttcttc accaggcatc
    61921 tcctctaaac gaccactcat ctctctaaga gcctcagccc atcttgatgt agagtctgcc
    61981 ataagtgcaa cactatatcc catatctcta aaatattcag ctattgtaat accagtgtat
    62041 atagaagctt cacgtgcagc aaccggcata tctgatgtgt ttgctataag cacagttctt
    62101 tgcataagtg actcgcctgt tcttgggtct tttaattcag gaaattcaag aagaacatct
    62161 gtcatttcat ttccacgctc gccacagcct atatatacaa ctatatctgc atctgcccat
    62221 ttagcaagct gatgctgtgt aacagttttt ccacttccaa aaggtcccgg tatagctgct
    62281 accccacctt ttgtgattgg gaaaaatgta tctataactc tttgacctgt aacaagaagt
    62341 gaatctggtg ttttcttttc tctatatggt ctttcttttc taactggcca tttttgcatc
    62401 atagttacag gtatatcatt acctttttca tctgtaataa cacaaactgt atcttcaaca
    62461 gtaaattcac cagaatatat ttcttttata gtacccttaa ctccataagg aaccataatt
    62521 ttacattcta ctactgctgt ttcttgaacg ccaccaatta tatctcctgc tacaacctta
    62581 tcaccaacag attttttagg tttaaattcc cacttagttg ttctatcaag tgaagatact
    62641 tcaacacctt tagttatatt agtacctgaa atatcataca ttttttcaag tggacgttga
    62701 ataccatcat aaatagttga aataagacct ggtccaagtt caacactcat aggcattcca
    62761 agagaaacta cttcttcccc tggtcctaga ccggaagttt cctcataaac ctgtatagaa
    62821 gctttatctc catgcatttc tataatctcg cctataagat gtttatctga aactcttacg
    62881 acgtcaaaca tattcgcatc tctcatgccc tccgctacaa caagcggtcc tgacaccttt
    62941 acaattgtgc ctgttttcat attctctcac ctgcaatcat atactttatc aaaatttaaa
    63001 tattccctcc tatattttat tagcacatat atttagcacc aataaaattt gagattgtct
    63061 tttattcaac tttcatctat tctttaaata atatatctgc acctatagca cgtttactag
    63121 attctcttac ttcattcata cctaatccca tacttcctcc aatacctgga ataactataa
    63181 tggcaggaag ttggtaatct ttgtattttg ctattgattc ttttgcaagc aatgatgcct
    63241 gttctgtaat ataaattatc gcatattcat cttcaaccaa cttatgtata ctttttttaa
    63301 tttcgtcact atcataggct gggaagatat ctattccaag agctaaaaat cccatgatgc
    63361 tatctttatc tccaactact cctaccttat acataagcat cccttagcct ttcttttata
    63421 gtatctgcgt ctatattatt aagcttacta gtcaaaataa ttctaattgt ttttatctct
    63481 gattctttag catataaata tgcaattagt ggttctaatg taagaggctt aaattttgct
    63541 cctctaacat attccataag atagtcatca caaagttttt caaagacagt aaaaccacta
    63601 tccatgccat ttttacagac atcagagtaa gaagtagatt taaaacatga tgctggagta
    63661 tctgaggaaa aagcttctaa gaatttttcc ttatcaagtg agccacctga aacaaacaca
    63721 ttcataaaca tatcaaaatc tttcttcata tttttgactc ttataaaact ctttagattt
    63781 gttaaatcac aaactttcat aacataatct attacaaatt tgttttggct ttctttagca
    63841 gtttctttca tactggtaaa ggttgcttta tctagaacaa tatcaaccat ctggccattt
    63901 tgtgtcttat tataaacatc aaatgcctct aatatagctg atgacattat cttaggtaaa
    63961 tcactaaaac tacgatttgc taaagattct ctaagcttaa taagaggaat tgtacctcca
    64021 tcaattaaat atttctcacc atctacacca gaaatttctt ctttaatcag cacttttaaa
    64081 ttgtgatagt catttttata aagaaataca tcaacaaatt tttcttcagg agctagactt
    64141 ttaagaattt catatgtctt tgataattct tgagtcaaaa tattctcaaa attatgtata
    64201 ttattatttg atgtatcagc ataacctgcc tcagctataa ttcttaaaga gtcttcaggg
    64261 cttttggctt ctgccatttg aataaacatt tgtctgttaa gaagctgttt ttcaagcact
    64321 cttattcgtg caacggcata gggataagtt ttttcttctg ccatttttta acccctcctt
    64381 aattaaacaa aatttctgct gcaatttgtt caatatattc atgctctact gcaattatgg
    64441 cttcaaatga ataattgtac tcaatgtcac cttttttaac tatgaaacct ccagtaatat
    64501 ctctagtttc atcagacact ttaatgcctt tttttgatag cacatctttt aatgtttttt
    64561 tatctttttt agataatact atctctgaat catctgtaca atttgatttt tcaatcatgt
    64621 ttagtataat ctcttcatat tcattatctt taagatttaa aagtttgttt ttagcttcta
    64681 aaattacctc ttctaaaatc tcttgttttt ttgataatat ttgcttttta gcctccatat
    64741 aagctcctga tatttcctta gaagccgctt tttctgcttc tgcctctgca agctttgtat
    64801 aggaagccat ttccttttca gctttttcat tagctgaatt tacttttaaa tctgcttcac
    64861 ttttagcttt atccaatatt tcttgtgctt cttgtttggc atcagctata attctgtcaa
    64921 tcattttttg ttcattaccc ataggagtgc ttcctccttt tcattttttt tacttatgaa
    64981 ttataattta taattaacca attgcaattc cattgtaagc taagaaagaa acaagtagtc
    65041 ctaaaagagc atatgtttca actattgctg caaatgttat agctttacca agttcttcag
    65101 gtctttttgc aactattcca actcctgctg ctgctgcttt accttgtgct atacctgata
    65161 ctaaaccaac taaaccaatt ggaagtcctg ccataagaag ttgtaaacct tgagctgatg
    65221 ttggtattgc atctccacca ataatccctg cttttgataa aataaggaaa gctatgataa
    65281 atccatacag accttgtgta ccaggaagaa gttgtaaaac tagaagttga ccgaatttac
    65341 tagggtcttc tgttacaaca cctgctgcgg cttgacctgc tattgaagta cctttagcag
    65401 aacccatacc tgcaaataat gctgctatag cagctcctga tattgccaaa aattgaccat
    65461 ttcctaacgc gtttaaaaat tccatattta catctccttt ttattaatgc ttgtatattt
    65521 tgttttatac ttaaacggaa caaaaggaac tcctccgcct tcataaaact tattgaaaaa
    65581 ttctacatac tgtaacctac ttgtatgaac atatgcacct agtgcattta taagaaggtt
    65641 tattgtgtgt cctacaacac caattacaac tgcaagtatc ggaccagcta tagcccctaa
    65701 aaggttgata acttgtgcta taactcctgt tgttaaacaa agcgccataa ttcttgtata
    65761 agataatata tcagcaaaat aacttgttat accatagaga cttgaaaatc ctttaaaaag
    65821 cttaacagga atacctttaa agcttcttcc ttgagtaagt acaagaccta tagcacctat
    65881 aattgctaaa tattttccta cttctgaaaa tacacctatg tcccctgcaa caaaaggtat
    65941 tataagtaga catacacctg ttatacacaa ataccaaaaa cctatgtcaa agattgcatc
    66001 tattaccttt ccacttctta ttaatgtata tgcttttatt cccaaaccta catatatatg
    66061 gataataccg aacagtaacg acattcccat aagtgtcata acatcctcta aaggattaat
    66121 taatgctttt ataggaatta aatcccccaa aatacccccg aatataagac cccatacagt
    66181 agttgaaact ccacagatac caataagttt aattaaattt ccttcacctt tttgtatctt
    66241 taatttatat acaacaaatc cacaaactac tgcaattatt aacccatatg cggcgtcact
    66301 tagcatcatt ccaaagaata taacaaagaa gaaagttaaa attgtatttg ggtcaatatc
    66361 ttttgtactt ggatagctgt acatgttagt tacactttca aaaggtgtta ctaatttatt
    66421 gttttcaagc agaattggga agccttcttc tttacttcct tcttcagtct gaacacaaca
    66481 atcaaacttt tctgtaattt ctttaattaa ttcatctgcc cttttgcttg gtaaccaacc
    66541 attaagacag aatgttgttt ttgttttgac aagtctctct ataatctttt tttggtctct
    66601 ttctatagtg taaaaatcat ataggttttc aagcatgtgt atactatctg catgtctttt
    66661 aatttcctct gttttgtcct tagaaacgtt ttcctgtcta attatcattt cattgtattt
    66721 cttgatagct tgtaacggtg taccttcttc atttggtaat gaaaccactg aaaaattaaa
    66781 ttcttttaaa acttctaaaa catcatcaaa agtttctttt aaagtaatta aataaacata
    66841 gttcattaac ttgtcagaat tgacaatccc aataacactt tctggtattt catcttctaa
    66901 ttttactctt aaagcatcaa tgtttgcgct tatgggcaca gttccaagta tagtttttgt
    66961 atacttagtt tccatatttt caataggaat atcaaagttc acccatggtt ctaacatact
    67021 tttattgttg ttaagtaagt ttatgttaga ccttattgta cctatctcct tgtgcaaatt
    67081 gtttaactcc agagcttcag cataaacttg cccttctttt tcactatcaa ttttgttaaa
    67141 ctctcttttt ggtgcaagta gggatttttt ttgtttcact agtgaagaaa caatattaat
    67201 tgcttggttt acatgagaca ttttctgctc tagcattata acttcagatt cttcactatc
    67261 ttttacaaga taatttttta attcctcctc ctcagtaaga aaggcactat catcaatctg
    67321 aacaaaccca cggttcataa gtagctttaa aatctggctt ttttgagctt ctaagccaac
    67381 aatagatatt ttgttcatat taactattgc catattatct cactaccttt ccaataaccg
    67441 cttcaatagc cttacttttt ctttcttcag cagttttttc aattttcaga cattcacttt
    67501 tagcattagc taagatttta tcaacctctg ctctactgtc ggtgactgcc ttctcaataa
    67561 gagtttcttc cataagcttt gcttgttttt ttacatcagc aaatatgctt tcacatttgt
    67621 ttacagcatc agctctgata gactctgcat cagtaacagc ttttactttg atactgtctg
    67681 ctgtctgctc tgcctcaaca atgcttttta ttatttcaaa agccatccaa atcacctctc
    67741 ttaccttttt actatgtata taaccaatta gattttttta ttctaattag attactacct
    67801 cattgttaaa gtataaacag catttttata taataattaa tatttttcaa cgtttatttc
    67861 ttaataaaac atattttaga atagtacttg cctagattta catccttttt tgacttactt
    67921 ttagactatg acatgagtat ggtttttaaa taccattatt ttcaataatt ataatttaaa
    67981 gcgatatagt ttgtcaatag cgttattttg ttttaaaatt aacgttatgt cgacatttta
    68041 aatttttatt ttattttttt tataatttta atttaattta ttacatataa aagtttttta
    68101 tattcttttt caacctctaa ccattgaagt ttattgtttt ttttgaattt ttagaaatat
    68161 ctcgcactat tttatctaac ttttataaat catcaagcta tatcgatttt tgtcacctta
    68221 tttttaatct aattttttta tatctagtta gaaataaatc aatattttta aagattgata
    68281 aaacttacac ctagttctaa tagttttatt ttaaggcaat gtattaatct taagtagata
    68341 atatcattag ttactctata tattcgacaa cattataaaa aaatcctcgt accaatcact
    68401 ccaatcttca ataggatatg ctgctcctcc atttacactt ttcagtagat tggatgtata
    68461 ttcttctccc atagaaaaaa gttcccctac tgtcatatca taacctctag atgtaacaac
    68521 cttacaaaat gaatccataa catcacgttg ttctcttgtt tttataagtt cctttctaaa
    68581 ttcatcatca ttcttagctt cttctaaaat tttagttaat ttttcattca ttatgtattt
    68641 ctccttttaa gtagtctttc tgtaaacttc aataagcttt atataaaaag gaagccatcc
    68701 taaataaact aggatgactt cgcttaactg ttagcaacac atttactagt ataaaataat
    68761 tggtgtacct ggttctatat tttcatatat tttctttgcc ttagaaaaag gtgtatttac
    68821 acatccatgt gaacctgaag acttatatat acttccacca aaagaatttc tccaagtagc
    68881 atcatgaatg cctatgttcc cattaaatgg aagccaataa cttacaggtg aactgtaacc
    68941 ttgaccagtt aatgaaacat ttctagcctt ataattaaga ggatatatac ctgatggtgt
    69001 agcaaatcct ctagctaaat cacctgttac aacgtctgtt gatacaagca tttctccatt
    69061 tttaaagaac cacatatgtt ggccagaaag actaatctct acatatgtat ttccaatatc
    69121 atctttatta cgagatacag ctttttgtat gtaaataggt tctcttgtaa catttttacc
    69181 agcttttaca acatcaacta atgcttcagc ttctttcttt ttatctatca accaaccata
    69241 aattccacct gaaattgtaa tatctttacc tgtggcagtt ttaaatggtc ttgagtcacc
    69301 aaaagtactg tattttttac ttaaacctct tgtatattct accatagcat cattatcaaa
    69361 agttatgtca taattctttt ctgagtctac ttttaaccat ttattaattt cagaaccatc
    69421 taaagtttcc ttacggtcac taaaatcata tgtaacgact acaccaacat acttatctaa
    69481 tgtcttaata gcttgtttca acttttctga atcctttgtg ttgtttggtg cttcataaac
    69541 tttactttca tccagagaaa tagaagtatt cccagaatta attgagtttt gtactaactt
    69601 ataaaaatca tcttttttca ctttgtttcc aagtacctct ggtactataa cataagcgtt
    69661 tttagtgcta tcatacttag gataagcact cttaggttct acaacatttt tactatcaaa
    69721 acaagataaa gcattaaacc ttttttctag taaatcttta ttatatgaaa gagttatcat
    69781 attattatac tctttagatt taaatattcc accaatccat ccaatagcgc tctgactatc
    69841 ttttatcttt tgaactttat catctggtgt aaattttaaa tcaatatctt ttgcttttat
    69901 ttgttctttc ttattgtttc tttcctctaa gtttaaagta taggaattag tactagatgc
    69961 taacaaatca tttacttgct caactgtttt tcctgaagcc tttacgccat taatagtcgt
    70021 tccaaagtaa aaatgatttc taaaaaagat tgccattcct atataagcta caaacaaaac
    70081 acctactact atagctatct taaattttag atttttttgt ccactttctt gttttacctc
    70141 ttttccatca atcataatta aatccttcct tacattgtaa ttacctatgt accttattgg
    70201 tttttaaaca aaaccatgta tgccttattt tatataccca aattactgta tcattattta
    70261 tatttttaaa tatatagtta tttctataaa accattttat cttttagata aaatgattat
    70321 tataaatccc cccctttcaa aatcccttaa acacaatctc tgctatatta atatattacc
    70381 atacttttaa taatcgtggg actatctatc tatttttgta acactaaact actattttaa
    70441 aaaagaaact aattttgtgt tagtttcttt atcttaactt atttttatat tgaattttag
    70501 cttaacataa cgttgttata tagattctat ttaattattt tagtttctat atcttttcca
    70561 tctgcatatt ctttaagtaa ttccttagca tatccaaaat attcttcaat atcagattct
    70621 tgactaaaag aaaatataca aattaatatt tcatttgcat cttctgttat cattgctctt
    70681 tcagaatcac tagttggact cccaaattta cccactgaat cagacaatat aggaagattt
    70741 tctatattta ttaattcttt cccaataccc ttatactgtt ctccttcatc tcctacagta
    70801 aaacatactg gtgaatgtaa tttgcttaca ttatatgtac ctactggata taatgatttt
    70861 attgatatta aattgtttat ttctactata ttatttattg tataaagacc cttcccttga
    70921 ataattcttc taaccaatgc ttctgaagat gttctatatc tacttggatt ttttccaagc
    70981 tctttataag catttcttgc atctttaatt ttatctagtt tcgtaatgtc ttcaactttt
    71041 agactttgat ttatagtatc acaaaactca tttatttcat taattaattt ttctgagctt
    71101 ttatttactg ctacttttgc ttgaatgcaa cccagcttag cattaggcca tctttcctta
    71161 agtttgtcat caatacttat atctatcata cttaaacaac tcctatacac taaattttta
    71221 ttaaagtttt tatcatctat acattatagt actattcttt tgttaataac atgtttatta
    71281 gcaaaataaa tttattttta atataatttt tataaaatac aattattttt tgctttatat
    71341 tagacaatac attgataaaa taaaaaaaca ctaattattt agcaatgatt tattaaaatc
    71401 aagcattcat aatagtgctt tatataaaaa tcaaattttg ttttaaagta aatctaaaaa
    71461 attcttagct ggcattggtc gtgcaaaata aaatccttga actaaatcac atccaaattg
    71521 tttcattaac tcagcttgtt ctttactctc aacaccttct ataattacaa ctaaatctag
    71581 tgattttgct agagacacta ttgattttgc tatattgcga cttctctcat catgttcaat
    71641 gccaccaaga aaagacttat ctagcttcaa tatatcaatt ggcatatctc ttaaacaact
    71701 aatagaagaa tatcctgtac caaagtcatc catagaaata gaaaatccat acgtcctcaa
    71761 ctcatttaaa acattcttta aaatatttaa ctcattaata gccacagttt ctgttatctc
    71821 tatttcaatg aaatctgaac ttaaattata catttttatt gttttattga taaattttac
    71881 aatatctggt tgatacaact cgaccctaga taaatttact gaaactggaa ctatcttttt
    71941 accttgcttt ttccattcat ataaatcatt gcaaaccctt tcaaatacaa atctcccaat
    72001 ttttaaaatc aacttacttt tctctgctat tggaataaat actgcgggac ttataaaacc
    72061 atgttctgga tgattccatc ttattagtgc ttcactccct atcatttctc cagttacaag
    72121 tgaaaactta ggttgataat acacttcaaa ttgatttttt accaatgcta tttttatatc
    72181 gtctaaaatc attgattcct cactaagctt attcctaaca tcttcattat aaatagcata
    72241 atttatattt ttacctttag caacagacct agccatattt gctttattta cagccttttg
    72301 aatatctact tcaccttctt caacaaaata aatacccaca cacagagaaa tttcaaagac
    72361 tatactcaaa ttactttcaa tattacttcg tatattatca agttttctta taattttatt
    72421 tcttccattt ttataatcac agaaaattgc aaaataatca cttgaaagtc gtgcatatac
    72481 ctcaccttct gttaattctt cttttaaagc ttttgctatt gtaattaata aattgtcacc
    72541 aaattcatat ccaaaagtat cattaatcat cttaaagtta ttaatatcaa aatatactat
    72601 aatataattt aaagatggtt tatctaaaag atacttacta cattctctat aaaatttatt
    72661 ttgatttcct atatatgtaa ctttatcttc ataagccaaa cttaatattt ctttttcatt
    72721 agattttttt atataaatta tataaaaaat aattgcaaca aatattaata caatagataa
    72781 cactgcatat acagctctgt tgattatttg ttttgaatta ctaaatacaa cagtttctgg
    72841 aattgaaaaa attaaattcc agtcttttat ataattattt tcactattcc cattatccat
    72901 agtggcatac cctaaatatc ttctttcttc caacatattt aatacagttg cacctgtttt
    72961 attttcttgc aattcttttt ttaatctatt tacttcttga atatcattat cctgttctaa
    73021 caatttataa atattttttg ataggctatc cccttgtgga tgaaggataa ttgtaccatc
    73081 attttttaca acataagata tactattatt ttcataaaaa gatatattaa taagtttcat
    73141 cagagtattg atattgtaag tacaatataa aactccaact actttatcat tatttaataa
    73201 tggtactgaa atagcaatct tctttataga cttatttact tcatcaacat atggacttga
    73261 aacatacttc ttacctttaa ttgagttttt gaaaaattct ctatctttca ctgaaaactt
    73321 atcacctttg gtattttcag cattaccatt tatatcaact attgccatag tgtaaaattt
    73381 ttgattttcc atttcatcta aaagattttt cattttttcc tcattaggta tatctggatt
    73441 tgaagcataa tagttagaaa aaatatttaa aacatctaaa tctttttcaa tttgtctttg
    73501 tgctagttga gagccttgta ctgcaacttc ttttatatgt atttttgcct ctgacataag
    73561 aagatgtttt gtatcttcta tatagatata ccccattgtc aaaaataatg atgttaaaaa
    73621 aagaattgta attaatgtaa aacttttatt tctccctgtc attcgactcc tcccctaatt
    73681 agtcaatact tcatatagat aatatatcct ttttatacca attcatcatt tatattgtat
    73741 ataactattc ttaaatgtta cacataaaat caacataata accataaaaa cattctttta
    73801 ttattataat aacactattt aattgaattt taaattaaag aataaaaact atccattttc
    73861 tcaaacaaaa aaactcttat acaataaaac tttgttttat gtataagagt ttttatttta
    73921 tctattttat agcaaactta tcttccataa tatgaattta aatacatatc ttttatttca
    73981 ttcataagtg gatatcttgg atttgctcct gtacattggt catcaaatgc ttgaattacc
    74041 atttcatcta ttgaatccat aaacttagat tcttcaacgc caaactcttt tatagattta
    74101 ggaataccaa ctttaagttt taaatcttca atagctacca ataaactttg gaatttctct
    74161 tcatcagaat ttccttttaa tcctaaaaat gaagctattt cagcatatct ctttaatgct
    74221 tctggatatt tatattgaga gaatgctccc attttctttg gtgcatctga agaattaaat
    74281 ttcataactt ctgttatcaa aagagcattt gcaacaccat gtggtacatg gtggaaagca
    74341 cctaatttat gagccataga gtgacaaaca cccaaaaatg catttgcaaa agccatacct
    74401 gccattgtag aagcatttgc cattttttct ctagcttctg ggtcttttgc accattatca
    74461 tatgcacgtg gaagatattc aaatatactc ttaatagctt gtaaagctaa tccatttgta
    74521 taatcggttg caagcataga tacatatgct tctaatgcat gagttaaagc atctatacca
    74581 gaagcagatg ttaagctttt tggcatattc atcatcatat cagaatcaac tatagccata
    74641 tttggcatca gttcataatc tgctaatgga tattttactc ctgtatcttg gtcagttata
    74701 acagcaaatg gtgttacttc tgaaccagta cctgctgatg ttggtatagc tacaaaatta
    74761 gctttttcac ccattttagg gaatgtatat accctttttc ttatatccat aaatctcata
    74821 gctaggtctt ggaaatctac atctggatgc tcatacaatg tccacattat ctttcctgca
    74881 tccattgcac ttcctccacc tatagatatt attacatctg gattaaattc tctcatagct
    74941 ttagcgccta tcttagcaca ttccaaagtt gggtctggtt ctacttcaaa gaatgtagtg
    75001 tacttaatat tcatttcatc taataaatca gtaactgctt tagtatatcc attattgtaa
    75061 aggaatgtat ctgttacaat aaaagctctc ttcttattca ttacatcttt aagttctttt
    75121 aatgctactc ctaaacaacc ttttttgaaa taaacttttt ctggtgctct aaaccaaagc
    75181 atattttctc tcctctcagc tactgtttta atattaagta aatgcttaac tcctacattt
    75241 tcagatactg aatttccacc ccaagaccca catcctaaag taagagaagg agctagttta
    75301 aaattatata agtcccctat accaccttga gaagaaggag tattaattaa aattctacaa
    75361 gttttcatgg ctgaagtaaa cttatcaagt ttttctcttt gatttacatc atcaatatat
    75421 aatgaagatg tatgcccaaa tccaccatct tctactaatt tttctgcttt tctaactgca
    75481 tcatcaaaat cacttgcctt gtacattgca agtactggtg aaagtttctc atgagcaaaa
    75541 gcttcttcta tttcaactga ttctacttca cctattaaaa ccttagtatc tactgggact
    75601 tcaaagcctg caagttttgc tatagtacaa gctgtttgcc caactatttt agaatttaat
    75661 cctccattta ctaaaattat atttcttatt ttttctgttt catctttatc taataaataa
    75721 gcaccacgct ctttaaattc ttttttgact tcattgtata tattttctaa tactataacc
    75781 gattgttcag aagcacatat cataccattg tcaaaagtct tagatacaag aattgagttt
    75841 acagcagttt ttatatctgc actatcatca attattgctg gagtattacc tgcaccaact
    75901 ccaatagctg gttttccaga tgaatatgct gatttaacca ttccaggacc tcctgtagca
    75961 agggtcaaat ccacttcttt cataacagtt gtagttaatt ctaaagatgg ctcatctatc
    76021 catcctatta taccttcagg agctccagct aaaacagcag cctcaagaac aacttttgca
    76081 gcctctatag tagaattttt tgctcttgga tgtggagaga aaattattcc atttctagtt
    76141 tttaaagcta aaagtgcttt aaagatagca gtagaagttg gattagttgt aggtacaact
    76201 gctgcaataa cacctattgg ttcagcaatt ttagtcatac caaatgcttc gtctttctct
    76261 ataacaccac aagttttagt ttctttatat gcattatata tatactctga ggcataatga
    76321 ttctttataa ccttatcttc agcaattccc ataccagttt ctttttgtgc cattatagct
    76381 agaggaactc tttgcttatt agctgccaaa gatgctgcta aaaaaatttt atctacctgc
    76441 tcttgactat atgtagcaaa tattttttga gcttctctga tttttgctag ttttttaact
    76501 aagctttcaa cgttatttac agtatctaaa ccaactgaca taacttcatt ttctttttta
    76561 ttttctatta ttacttgttc tttatgagcc attttaacaa cctcctgaga tagtttttta
    76621 tttattatgt taatttatta acattatagc atttactttt cctattttca agttattttt
    76681 ttaacatttt attttttatc taatataaca tcatttctac taataatatc tagctttaca
    76741 aatacttaat ttaactagat atcactttat tttttacgca aatcactaat gaaatcatct
    76801 aaaaacttaa ggataacgtt atttttttaa cgtttatatt tttgtatttt ttgcaaataa
    76861 aactttataa aaagaatttt taatatgata ctctatcaag tttaaaaata aaaatccttg
    76921 aaaatgaaaa ttaaaactta attaacaagt taaagtaaat atagttaaat gtacaaacat
    76981 ttacaacata tagtataatt aaaaaaatat atattcatga tttttatata atatgaaata
    77041 aaatatattt aatattatat agataaattt gaagtttata agaaggagga taagcatgga
    77101 aaaattaaaa acaattagcg ttttttcttt gattataagt gtaattttaa cgattggagg
    77161 tattggaata gtaacttatt atgtagataa tttgtttatt agaggactat cagtatttgt
    77221 tttaattatg tcctcttctt ttgtatcaac aacagttaga ttgatatttg aagagtcaaa
    77281 acgatataaa ttctaattta aaaattggat taagtaaata attttaatat agcaaaaatt
    77341 acggagatta gctcaaaata gactttttag tccatgaggc atttttttgt atgaaattaa
    77401 atatattttc atcatttcaa caagaaaaag aggcttctct ctattttgag acagcctctt
    77461 tgctagtatt gtatctaata cataatatta taagaaccaa ttctattgat gtggactttt
    77521 tataacaggc tgtagctgtt tgttctctag agcaagttct atagttggaa ttattagctc
    77581 agtatgtgca atcatagaat taggctttgc tttgcaatta tcttgaccaa aaggtacaaa
    77641 atatatattt ttagaattaa ggagaatgcc aatatttttg aaattaaagc ttagagcatc
    77701 attcgttgat attgatatta ctagtggttt atcattacga agatgacctt ttgctgccat
    77761 taatactggt gaatctgtaa taccatttgc taattttgca gcagtatttc cagtacaagg
    77821 agctattatt ataatatcag caattccttt aggtccaaat ggctctgcct cttcaatcgt
    77881 aactataggt ttatttcctg taagttcata tgcttttttc ataaactctt cagaatttcc
    77941 aaatctacaa tcgatatttt gtgatacatc tgaaaatata gtgtgtacat tagctccttc
    78001 tttaaccaaa ttctctaact ctataaatat tttatcataa gtacaaaacg aaccagtaaa
    78061 tcctactcca attgtaagtc cttcaagtct catttctaat cccttctttc atttataata
    78121 ttttctatag cgttaacaag aatttcacca gatgtctttg gtgaatattt accaggaagc
    78181 ccaaggcaaa gagtcgcatt aatccctgct tctttaacaa cagaataatc tactcctcca
    78241 ggagaagaag ctatatctat aatagttact tcttgtgata ctttttctaa cctttctttc
    78301 gttaaaatac actctggtat ggtgttaaaa atataatcaa attgtaaaag tttttcatca
    78361 agttgactta aagaaatact ggaatatcca aatgcattag ccgtacttct tgcatcatta
    78421 tttcttgcgc caacacatac atttgcatcc aaagcgtata atttttttgc aagtatttgt
    78481 gcacatcttc cataacctaa tactaaacag ttactttgat gtatattgat tatacttctt
    78541 ttaatagctt ctgctatagc cccttcagct gtagcaactg catttaaaat agcaacatca
    78601 ttcattttca taaaatcata aatctgaata gagtgttgct cgcaaaattt acaaacttta
    78661 gttggtatgt tacctccaaa taatatttga ttaggagata aattaattag caagttatca
    78721 atagtagcat caagacaatc atccgtattt tcaatattaa cttgattctt tgtaaatgga
    78781 attggacata aaataatgga acttttggat agtgcttcag ctagtgaagt tgattttcca
    78841 acgattccat ttataatttc atttgatatc ccataagtga ctacagaata ccctttatta
    78901 attagttttt ttaccatgta cacttgtcgc aggtctcccc caataacagt tatatcgtat
    78961 tgatttgaca tattgtaagc ctcctttact atatacaata tgtttttatc aatacattgg
    79021 ttcactaaaa ttactaaata ttatacttat aacattttta ataatgctaa tctatctatc
    79081 ttttcagaag aggtatatgg aaatgaattt aaaaagataa ttttctttgg gatttcattt
    79141 ttcattagat tatctttcat tttaatcaac aaatctttct tcgtaatttt gtctatagtt
    79201 attacaaata atacaatttg atttcctctt atagtgtctg agtacggcaa tacaattgca
    79261 tcttcaattt gaggaatttt tttaacttca ttttcaatct tagtagaact aactttaaat
    79321 cctccaatat ttaaaatgtc atcacttctt ccttcaaata ttaagtatcc atcattatca
    79381 taatatccaa tatcattgac agaataaggt ttggttgcat tatatactgc atattctgta
    79441 ttcacaaaaa tttttccttc tctaatatat atatctattc ctggaaatgg tctgcctaca
    79501 cttagaggtt tttcaattag ttcatcatag cataaatatg taatataatt taattcactt
    79561 gccccatagt ataaaataat ttcagacttt ggcatatatt tttttagatt tcttgcagta
    79621 tcttcaaata ataattgaga ccctgtaaaa atacttacaa ctttgagtac tggttctttt
    79681 aagtgtttaa ccaaaagttg aagttttgta ggtataaggt atatgttagt tacattatat
    79741 tgttttatta tccttatcca tgatttacaa ttaagacctg aacttattac aatactacct
    79801 ccttcatata atactgacat tatagaattt agattccctg taaaactaag tgttccatta
    79861 acaaacaaga ttgattcccc agagatatta aaaataccat tttgtatagg aaaaaatcca
    79921 gcccaactct catatgttct atataatacc tttggaacac ttgtagaacc tgaagataaa
    79981 gctcccatac aaatactttt atctaaataa tttataaggt tcttatattg atacatatat
    80041 atattaaatt taggattaaa aatagaaaaa ttaacttttt ttgctacttc attattgtta
    80101 tcatcatata aatcaataac gtccatagat tcatcagata taatgattga aatattattt
    80161 tttaataaaa tatcatctaa tactttttta gaaagattat aatgacaaat aataggaata
    80221 ttttttgaat aattaatagc aaaaaaacta atcaactgaa acattatatt tttagaatat
    80281 attaaaattg ggatattttc acctaaagaa atttgttttc ctagttcctc actataactc
    80341 aatatatttt cataagtata tttttctcca tctataatta aaaaattttt atttttatgc
    80401 ctctcttttt ttattcttaa aagttcataa tagttcataa tctacaccct ttcaagcagt
    80461 aaagctgaac ctagaccacc agctgcagct atagagcaaa ttccatatct acccttagtc
    80521 ttttctaatg cttttaaaag atgtaatgca ataattgcac ctgaagcacc atatggatgt
    80581 ccatacgcta aagctccacc aaatatatta tatctatcta ttaactctgg atattttctt
    80641 tgaaacaaca catctataac tgcaaatgct tcattaaatt caacagcaga tacatctaaa
    80701 taattaagac tttctatctc taaaagttta tccattgctt gtatcgctga tgttggactt
    80761 aaggttgcat ctgttcctat tgtgcatgta ttaataattt ttgctttagg cttctttttt
    80821 acatgttcta aatacttctt agaacatatt ataataaatg aagctccatc attaataaga
    80881 catgaatttg ctgcatttgt aatagtttct tttcctaaaa ttgatggcat cctatctaat
    80941 aacctttgac tcatcttatc acgtatacct tcatcatagg tactattatt tataggagat
    81001 ataatatctt caagtatttt ttcctctctt gcttcttttg ctcttttatg actttccttt
    81061 acccaaaaat ccaagtctgc tttctcaatt tgatataact ctgctactct ttccgcacct
    81121 tcgagcatac tattttggct attatcatca ggagaaaatt gagcaactgt ataatttgga
    81181 ttatttgtat tatatcgctt atcattctta tgatatgtgc gcattggttg tagagaacta
    81241 ctttcaaaac cacctgcaat aattaaatca cactgaccag atttaacctt tgaaaaagct
    81301 atgtctatac tcatcatagc agaagcacac tgcatatcca cagtaaaagc aggtacttca
    81361 tttgacactc ctgctgttaa agtcattaat ctagctatat tccctcctgt cccaactgca
    81421 tttccacata taatctcatc aattttatca atttcatact ttttaattaa atcttttaaa
    81481 acacttgctc ctagtaattc aggttgaaca aattgaaaaa ttccattttt tagacctata
    81541 tgacttctca atcctcctaa tataaaaact tccttcatac attacaccct tccttatatt
    81601 atagatttat catagatttc ttctgagtac attgttcagt ttagtgccta aaaaagatgc
    81661 aataactgac tttattgtat ctccaattaa aaatggtact actgctgcaa aaagtgctgc
    81721 ttctactgtc atttgattaa aatagcacat aaatactgtt cccataaaat atataatagg
    81781 cattccaaca aaaattgtta ttagtatata tctcttaata tcattatttc gtccttttaa
    81841 taaactaata attagtgctg caaacaaaaa cccaaaataa aaaccacctg ttgggcttaa
    81901 taactttcca ataccagatg tacctccacc aaatactgga atcccaatta aacctatcat
    81961 tatatataca ccaactgtac taaatgcttg tcttggtgtt aaaatcaaag ctattaaatt
    82021 tatcattatt gtttgtgctg ttactcctgc tggagtaaat ggcaatggta tatatatgta
    82081 agatgatata cacaataatg ctacacatat tgacatttta gttaaatctt gaatatttac
    82141 tttagtattt ttcattttta taattccctt catatgtctt atttcattta gtttatatgt
    82201 acatatacaa agcttctatt aaagctttgt tttagtataa aataaagacg tttttttgtc
    82261 aactattata agcatttagg tttacattta atttataagt aaactttata ctgttacttt
    82321 atattttaat agtcatttat aaaactttgc ttaaaaacag ctctatttag actatacttg
    82381 taaattataa tatgatatat ttttatataa gattttattt tatataaaaa atagtaacaa
    82441 atagtttata cacaagatat ttaaaaggaa gtgatgatat gaaagttaat gaaaataata
    82501 taaataatat agatgaagag ttagatgaac ttagtaggaa agtttactta gagtcaccag
    82561 atttttggat aagtatttct gacaaaataa tagataaagt atttgatgaa atgttattat
    82621 tttttgcagt taaatataac tatttcaata tagtatgctt tgctattgaa aacaattatc
    82681 tggatttaaa catgccttca aaaaacaaaa aatacactaa tataatggag catttgttag
    82741 atacatcaaa acagaatgaa gataaaaaaa tttataatta tcttctaagc ttaaataaag
    82801 gtaataacct agatgaaaga ccaattttag atgaattaaa ctgtaatatt agtagtgata
    82861 cttttgaaaa aaaagatata tatcttccaa agtacttatg tccaagttgt aattctaata
    82921 tatttgatac aggttataaa gtatcaaatg acataacata taaattttct tctaaagaag
    82981 ctgaacctat tgaaatgtgt agtgaagttt cttctatcag atgttgtaat tgtgatgaat
    83041 tattagaaga tattacactt gataaactat ataacctatg caaaattcaa aactgtaata
    83101 attgtggttc taatttaact aaggtaggaa ttattgcaaa gaaaaaaatg aactttgatg
    83161 agaatactga aaaatttaaa gatgtctcaa catcttactg ttgtggaaat tgtgactctg
    83221 aaataaactt atctcaaaga gaacatttta agatttaaat atttataggc taaagtaata
    83281 agattacatt attagatact gtataagttt tttaaatctg taaaaataaa tacacttata
    83341 agaattaaaa ttgctatgaa actagttctt gatgaactaa tttcatggca attttctata
    83401 atctaataat tattaaattt taacaaacct ttattagcat tccataatta tttaaaattc
    83461 tttcaaatac cctatagttt ataggtgaaa gtatctttaa tattatatca aacttattat
    83521 ctttaaatag taaatttgtt aaatctgaaa tacaccatac aattttattt tcctcttttg
    83581 tagctatatc aattctgatt aacttacatc tataataaat atctttatct tcatatagtc
    83641 tattttaaaa attactctta aaaaatcaaa tggcaaataa attaattatc cttttaatag
    83701 aatgtaatca tattatttac tatattccat tatgtactct ttaaatcctg aatcttcatt
    83761 tacttgttct tttactatat taaaaccttt tttattataa aacacaactg cttttttatt
    83821 atctttatat actgctaagc ttagactttt atatttttta gttgcataat ctaaaagttt
    83881 acctccgata cctagatttt ggtatttggg ctttataaat aaagctccta taaagctttt
    83941 atctattatg cttataaatc cttttatttc atctccatca tcatatacaa atgtatctga
    84001 tataggtata tattcgtttt taacagtatt atagttattt tgccagtatt ctttacttat
    84061 aaagtcatgt gctttgattg tacttttttc ccatatttcc atgattttat ttatatcttt
    84121 attgtttaat ttctttatca taaattttat ttcacctcat ttttgtattg attttataat
    84181 gtttataggt aagtttattt tatttagata tgatttagtt aatataaggt ggatgtttta
    84241 gtatatgcta ttgttgattc tacaatttta tatactgctt tattaatata aaataagttt
    84301 ctaaatactc gttgatattg ctaatattct acttatctac cacttagtta atataaaaca
    84361 atgatactgt aatatctaaa gatgttacat tggcaaattt acataccact tagttaatat
    84421 aaaaccatct tcagtatcat atgctgaaat attatcaaga tttacatacc acttagttaa
    84481 tataaaacgg caatcatgtc aagtacttct aatataaaaa agttctattt acataccact
    84541 tagttaatat aaaaccttac atggaaaacg aaacatattt aatttgttct gaatttacat
    84601 accacttagt taatataaaa caaatgaagc attgagttta aatagcgata ttagaaaatt
    84661 tacataccac ttagttaata taaaacttca atgaactagg gtttaaaata cattctagcc
    84721 cgaatttaca taccacttag ttaatataaa actttaaaat tccggacaaa caacgctaaa
    84781 tcaaaagaat ttacatacca cttagttaat ataaaactaa tagaattata gcatcaacta
    84841 atcgtaaaat atttatttac ataccactta gttaatataa aacttgcggt aagactgttt
    84901 gttacaggga tggcagagtc atttacatac cacttagtta atataaaact caactctcct
    84961 tgatagattt agcctatctt gcgatattta cataccactt agttaatata aaacgaacaa
    85021 atttaatgga agcaataaaa agtaatgacg atttacatac cacttagtta atataaaacg
    85081 gaggaactaa atttagctta ctttgataaa gaaagattta cataccactt agttaatata
    85141 aaactcaata tcttttctta ttagtttcgc aaattcttca tatttacata ccacttagtt
    85201 aatataaaac gaaggcaaaa actaatgact aataaagaga aaataaaatt tacataccac
    85261 ttagttaata taaaacatat ttaaagcaag tactttttta agaaaactta atttacatac
    85321 cacttagtta atataaaaca tggctaagag atacagataa aaatataaat gaatggtatt
    85381 tacataccac ttagttaata taaaactatt acgagaaaaa tttaaaaacg actaaaatcc
    85441 atatttacat accacttagt taatataaaa ctccatttat tttatatatt aaaattatag
    85501 cattcgaatt tacataccac ttagttaata taaaaccttt tgttttagga tgattatata
    85561 atattacaaa tttatttaca taccacttag ttaatataaa acttggactt attttattga
    85621 cttataaatt atctaattta tttacatacc acttagttaa tataaaacaa gcagaaataa
    85681 taggactaat atctatatca accaaattta cataccactt agttaatata aaacgataga
    85741 agaaaataat ataaaagtta ccctaaatta atttacatac cacttagtta atataaaact
    85801 tagaagatat agaagttctt gtagatactg ttgagattta cataccactt agttaatata
    85861 aaactaaatt taaaataaat tattaaatat ccgaaaaaat tatttacata ccacttagtt
    85921 aatataaaac ttttttttga gctgtcaagg atgttgaacc acacttattt acataccact
    85981 tagttaatat aaaaccccaa aataggtata tttgaataca ttgaaaacac ttcaatcaag
    86041 caattataat tcaataaaaa catcaaaatt tgcagtgagc gagcagtagt gcaattgata
    86101 acaattatca tacaccttca atcccttata ttccaactgt taacacctat tttagcataa
    86161 atatcgctca ctgcaaacct atataaacat ttcatcagaa tacttatcaa tcccataaca
    86221 tttcttttta attgaattag gattttttat ctcataaaca tagattgaat cctcgctatt
    86281 atcaataata ttttctattt cagaaataca tttatgtaac tttccttcag taatattgcc
    86341 ttcaaaaaca gaattttgcg tccaagtcaa atattttcta agtatccttc taattctatt
    86401 taacgacctt gcttcaacaa tatcataagt aacaataaca aacatactta ccaccacacc
    86461 tttaaaactt tgtacctttc atcatttata aaatgtttaa ttaatttata acactctaac
    86521 cttataaaca ttctatatga aacttttcta tttagatttc tatgttttat agttgtctgc
    86581 atcttatttt caaattcttg caaaaatttc ttctttcctt tttcacttaa ataacaaatt
    86641 ttgtcttgat attcaaaatc attcttatta attcttttat tattaatcag gctaaaaatt
    86701 attgtgtcaa ttataattgg cttaaaaatt tctgcaatat ctaaacttaa agaaaatctc
    86761 tttgttgatg gttcatgtaa aaagcttatt gtagggtcaa gttgtgtctt atatatctca
    86821 cttaaaacat tcgtatacat tatgctattt ccaaaagaca taagagcatt tactgggtct
    86881 ttgggaggtc ttttttctct tttataaaat tcaaaatcat cttttaatat ttgattaaat
    86941 gatttatagt atgtttttct tattctgcct tctttaccca taagttctga tatttctttg
    87001 acatcattca aatcatttag ttcatccttt atagtatcaa ttaaactttc atcaactttg
    87061 taatatctca tatttcttaa aatatggtat gatgcacttt ccacaaagga ttttgctaag
    87121 tataatcttt catttttatc taaatagcag gctgattgac atactaaact gaatcctgat
    87181 acatttttct tccttggata atatgtacct gaataatatc catagtaatt gtagaaatga
    87241 agcatcaccc catatttgct tatgtaattt ataagttttg tatttaaatc tacttctcca
    87301 tatatatgaa tatcatcaac ttgttctact ggtaatattt ttttctcacc ttctaaattg
    87361 taatagtaaa tcgtattttc tttccttttt atatccccat tacttataat ataatagtct
    87421 ttatacattg ttactcctcc ttcacaaaac aaaattcata ataagcacat tttgtacaat
    87481 aatgtttttt ctcaattttg ggaggagata actgcatatt tatttcattt atatttataa
    87541 gtgtgttttc aataattctt tctttttctt ctgtcaatat caattcttct tgtttctttt
    87601 ccttaacata atttatagta ccttttttct ctatacccat actattcttt aaatagtata
    87661 agtaatagta taactgcatt tcatctgctt ctttcatctt tgaacttatt tttacttctt
    87721 ttacatactc atcctttatt atatctagct tcaagatatc atcaatcaat atttctttat
    87781 ttttcattct tttatatgaa tcttcatgta ctatcttccc agacaatact ctactactat
    87841 tttgttccat ggttattcct ttagaaaata gccatagttt tcttttacat acataataat
    87901 aatttatttt tacaccttga acttttaata cttctaaatc tattggcaca aaatcacctt
    87961 ctttagtaaa ttttagccac attgttaata taaaaatcaa ataaattggt ctatttcatt
    88021 acttataagc acacctttac caaatatctg ttttgtatgc ttattttcgt atatatcata
    88081 tttatataaa agtattttta aatcttcaag acctttcacc tgtatgtcaa ttacattttg
    88141 tttagcttta tatattggta aatttacagt ttttttaatt atctctcttc ttgctttttt
    88201 tctcttagac tttattttat ttatcaattg tctatcatca ttactatatg catttataag
    88261 ctcttgtccc aactcttcat aatctttgat taaagtttct tcaattttat tatatatatc
    88321 ctctggaatt actgtatatc cttcaatatt tctaagtata ttttgtgcat ctttagaacc
    88381 taaactatat ggcgttatag tatctaaaat atttaaagca ctggtaaatc tcttttcaaa
    88441 agctgtacct tctagacttt ctttagagta tagtatctta accatttcta ccttatattt
    88501 ttctttcatc ttcacacatt cttttccatt tataaaagtt ttcagtagct caagtccttt
    88561 ttctacaata tccttatcat aaatactacc tattcctgta gctttttctg tatatataaa
    88621 tatatttggg ctattttctt catactcacg acttctataa catctaccaa atcgttgaaa
    88681 tagactgtca agtgttgaat tttctgtatg aagctcatca aaatcaatat caagagatgc
    88741 ctctactaat tgtgttgtaa tccaaattcc atttctatca ctattggcaa attcttttat
    88801 atatttttct aattttgctc tatcttcttg tatatacata gaatgtaaaa gatttaagtt
    88861 gacatctatt ccttttggtt taactatttc ttctattaac tcatattttt ctacagcact
    88921 tttaactgta tttactatta caagaacttt tttattcatt ccactttgta ttattttacc
    88981 taagttttca tctattgaat tttctacaat agaaacacaa tgtcttattt tttctgtatt
    89041 acatgtcaat tcagctaagt tactattcat tacacctctt ttttttaatt catctatata
    89101 tatggttggc atagtagctg tcattatcat aaatctgcca cctatcttat gtatcatttc
    89161 tatacctttt accaatacag ctgctatttc tggtgaatat gcttgtatct catctattac
    89221 tacttttgaa tatgctaatg ttgagtacac tttttcatac cctctataca aaaaaggaaa
    89281 tttaaatatt tggtctattg tagaaaatgt cagtttgcaa gataataact ttgctaaatc
    89341 tacaatctca cttgaatttt cttgattact ttcttctaga taatctattg ctgttgaatg
    89401 taacaaacct aagaatgtat catttgattc tccaacacca actatatttt ttgctctatc
    89461 aaataatgca tttatactta ctcttaatgg aagtgtaaaa aatgccttgt ctttatctat
    89521 ccaaattaag gcagtttctg tttttcccat tcctgtagat gcaatcagta ttatattctt
    89581 atttctatta gatttagcaa atgattgagc ctctctcaaa ctaccaaact ctttcattaa
    89641 ataattttct gtctgttctc ctatatttat aacattattg cattccacaa cttcatgagc
    89701 agaagcacta tggtctagtc tatgtagtat tccttttaac ataatatata aattatagta
    89761 cttgtgattt ttatctattc ttttttctac actttgtaga tatactttac tcaatttttc
    89821 tgtttttatt ggatatctaa ctttaaattc atgctgtagt tcataaactt tatttattaa
    89881 atcttcatct aatatttttt gtattaaatt tttaaaatct ttatctataa agatatctct
    89941 ttcatgatga tatacaataa cttgatttaa tactgctcta agttctttat tttttttcct
    90001 gtctatataa ctataatcaa taaatgcagg agaaagataa ttatggccta cattattttc
    90061 taaataagtt actattttag gttcatttat tttagtatcc attctgcttt ttattaactc
    90121 ttgaaacggt gaaaatgctt ttccaatatc atgaaattct ataacaaagt caagtaattg
    90181 ccaaaatatc tcctcttcta gaaaatctaa gctatttata ttttttccat aactttctct
    90241 taatacattc atttgtttta aaagttcatc agtatgttct ctaagtgttt ccactggatt
    90301 agatttagca tataacataa tctccctcct aatttatatt attaaaatat aataaatctc
    90361 cttcattatc taataatata tctccaattg atatagtatt tccatcctca acataataac
    90421 tatctacctt attccaaacc ctttttttat cttccacagc attattatca tagtaattat
    90481 tgagtctgta acttatacca tctatatctg tatcttgtaa acttgttttt ggtatatata
    90541 taggcattct tatattacat tctgataact tataattttc ataatcatct aattgtatat
    90601 cctcatctac ttcaaattta ttgacttcta caaatctaat atcattaatt cttactaaat
    90661 cttcttttct acctaatgat aagtgctcgt cataatttaa taaactatca tatatttctt
    90721 ccaataaatc aaaatcccca cctatatgaa ttatcaaatt tacattcaat agcatatgac
    90781 tattcattgg catagatgta atactatctt ttttataaaa atatgttgtc tggtaattat
    90841 taaatatact ttcatatgtt ccctgtacac ttatattaaa tggtatatat tctgtagcat
    90901 ttaatatttt gtgaattaat ccatttattg tagaatatgg aggcagtgga tatgtctctg
    90961 taatcttcat agcaaatggt tttttgtagc atgcagtttc ttgaaataaa tctaatttca
    91021 aaaccttcat attaattcac cccataatat tcctttactt ctttaactag ttgtccaaaa
    91081 aatttatcta cacttaaaaa attatcttca aacaatccct taaattcttc tttatttata
    91141 aataccccat ctaccattcc aacataggta aattctttta aatcttttcc taaaaaagta
    91201 ccttgaatta cttcttctat agcttgctta tttattttaa atccattttt atctcctttt
    91261 aatttaattc tacccaagaa aaatggattt gctatttcat atactcctcc tactacaaat
    91321 agaggagata aattttcttg tctacctcta atatttctat tcaatacttt tattatttct
    91381 aaaaattcta ctactcttct acatttctct ttattatcaa gttctatatc tccatcctta
    91441 cctattttag ataaatctat agtcactgta tatgtataat aacttaaatg ttgctctatg
    91501 ttagcaagat taggatgttc tcctattcta tctgctaatc ctttattatt taaaaagtcc
    91561 atgtcacttc tatatggctc aagggaaatt gcattactta atcttacagt agcttctcta
    91621 gtcaaagaac ctcctttttt atctttctca tcttttttat ttgttttcat atatccaaat
    91681 aaatccattt cttctgattc tcttatactt atattgtctt taaattgaat agtgcctttt
    91741 tctttatcga caacctgtaa attccaatta aacaattctg ctgctaatcg tactatgtca
    91801 tatcttaaac actggcgaga tgcaaatgta tatatatttc catcatctct acttaatttt
    91861 tttaattctg atatattacc tatcccttcc ccatagttta aactttgagc ctgtgctatt
    91921 actgtaaatg ttaaccctct tttcatctta tttttcctcc ttttcgtttg gtagtttatc
    91981 ttttccttca tattttccag aaattaatcc tgttacaaat gcatacccta cagattcaaa
    92041 atctaaatct tcttcaacaa atatctgtaa aatttcttct ggtggtgttt tttcacttgg
    92101 tgaaaaaatt cttaaaattg tttgcataaa atcattttta ttaccaacct taattaaatt
    92161 taaaatttta tatgttattc cttctatttt atttttagca ttcttatcaa tataataatc
    92221 atgtatttca caacctgact cataaatctt tctcaacttt ttatagtcca ttttatacac
    92281 tcctctctta tagttattta atattgttct taattgaaca acattgaaac aagataaccc
    92341 tgatatgttt gatttattat tgctttctaa attactctta actatattcc ttaaagtgtt
    92401 attaattaaa tgttttaagt ctttactttt taaaattaaa tctaacacat ttgatttaag
    92461 tttataatca tatatacttt gtattttttt attttctttt acaaaaaact ttgctaaata
    92521 agttggaata ttaaaataat ttattttaca ttttttagaa tctatacttg ctttaaattc
    92581 cacaaaaagt atattacgaa gttgccattc actttttaat gtattttctt ctactatact
    92641 ttttataagc tgattaaaag gattttcatc tttggaatct gaatactcac ttttttgagc
    92701 ttttaaacta ttatttcttt caaaaagctc atttatacaa gtatccatgt taacaaataa
    92761 ataaaactca ttttcttcat taattaaata attctttctt gtataagtag cccctgctgg
    92821 agtacagaac aatattagct tacaaatatc acatattgat ggtacatacg cctgattcca
    92881 aaacatattc ctagcattat tggtgcttac tccaagtgga gcaaaattac tttctgagta
    92941 ttcatctaat attcccttat ataaaccaca catttcacat acttctaaac tatccatata
    93001 cttttttata tcttctatgc ttttattttt ctttataaag tttttattta tttccttcat
    93061 aattttttct atagtattta tactagactt actaactttt ttttcattta tatccttagc
    93121 tatactattt aatctatcat ttaaatagtt tttcaacttg tcatagtcat tctcttctaa
    93181 taaatcttct aactctccaa aatatataat ttgtcttaaa taatcattaa acattacctg
    93241 ttttaatcca tctaaatcta atttcgcctt agcaacatta aaaaaactaa cttgtccaaa
    93301 ataattatct tgaactacat atttataaag atttgctgta agcctgtcat ttattgattt
    93361 tattttaaat atatctatag tctcatctac taaagcttct aaactatcaa attcatcata
    93421 actttttatc ttagacatac tatctagctt ctcttttatc atgttaaatt tttcttcatc
    93481 aaatttttta atcttatcat tttgttgttt cacactatct ttaattttct taattccatc
    93541 tttgattcta tcaggcttag atttaataaa atttatactg taatcaatat tttttttaat
    93601 tctttttgat acatcatatt catccataaa gtaattaaaa taatactcat gaaagttttc
    93661 aagaaataag ctatcaaatt cgatataatc ttccataata aatatttcag cttgtttatc
    93721 tgctttcttt attatattta aaaatccaac tatacccata ttaaaaaacc aatctcctct
    93781 ataaactctt aacttcattt atctcacctc cattctaaaa tatctacatc tccaaatccc
    93841 tgagcacgtc taaaaccaat tcctagattg tagataagat ttaaatcatc aatatcacct
    93901 ttcaatataa atttaccttt gtaaccatta atatattgat actctttacc tgttattttt
    93961 ttaaattctc ttaaactctc tttaactact acctttttga gacctatatt ttcaaattct
    94021 aactttcttt ttaatccatt ccccctataa tttttaacca cttcattagt tatatagttt
    94081 agttcttcta tgtatctatc atcagttatc tccaagaatt ttccttcttt agactttaca
    94141 cagattggag acaatgcatt aaatagtacc ctttcttctg ttaccttctt ttctcttgat
    94201 aaatcgattc taattcttgt aagttcgtag tctttatata aacatttttt agaagtcatt
    94261 aacccattgt atatatgaaa acccaattct aaatctggag tacttatatt taatattact
    94321 ttatcttcta taataaaatt gtcaccttca atactatact tttttatata aaccgaaaat
    94381 gtaaaatttt tagttttttt attattcttt tctttataat agtacatgtt tttatagtaa
    94441 tcttcattag attttcttat tgcttctttt ataatactca taaagagcga attataagat
    94501 attggtatac aacctgtact aaattcaatt ttcattttca taatatcacc tctctcaatt
    94561 aatatattaa cactagaccg tgaagtatat tggtccaagt ataaattatt tgaaaaaatc
    94621 agtaaatttt tttcattttt tcaatctcta acaatatatc atttctaagt ctatctggtt
    94681 ctacaacctc aacataagct cccatactta aaatccaact ttttatctcc tcataacctc
    94741 tcattttagc tttaaacatt atagatttat catcatattc tatgatttgt tgattattaa
    94801 cccaaacttt ctcctttata attgttgaaa atggatgact aatttttata acaacattaa
    94861 tttcttctcc cttataaatt cctatactat ttttactata ttcatcccaa ctaaaacttt
    94921 tatctacatt atatttttct tctaaaacct tataatcttt aatcctacat aatttaaagt
    94981 ctataaactt aaatcttttt tcacaaaaag ctaccatata agtatctgat ttataattaa
    95041 ataaaccata tggatgaaca attctttcac tatttcctga atttaatgaa taatattcta
    95101 tccaaaattt gtgttttgtg gtatatgctc taattatttc attacactta tttttttcag
    95161 actcataatc acaattacgt tgtgcttgaa ctgtaaaata atccatatat gtatcgcttt
    95221 tttctcctgt atttaatact gcttttattt tttctacaat attattaaat tcatttttgt
    95281 aaatatcatt attatactct aactgtgaat ttatcatatc tagaattgaa acttcactat
    95341 ctaataattt aattaatgag atgctattac atttatctat ttcataacca ccataaatcc
    95401 caggtgttga atttataaat ataccagctt gctctaaata catcttgtaa ctttttattt
    95461 gcctttcact tacttccaac tcttctgata attctttgca tttcattttg cctctgcttt
    95521 gaattaatat catcattcta agtgtattag ctaatttact aatgagtaac cccccctaat
    95581 aacattaatt gatattttta ttatttattt ctacacatat gtacatataa cctctttata
    95641 ttttatataa gtagaatttt tttataattt tgacatttac catattatat tttatatttg
    95701 tacaaaattt taatagttaa tacaataaaa aatattactg aaaaaataaa catctataat
    95761 tccagtaata ttaattaatt ctaaaccctt tttattatca tttaataata gtaactaaaa
    95821 attgactaaa tttaacctta tctcttttaa ataattattt cttacaatta aaaaataaac
    95881 tatttgaacc aagaacaagc ttcccattac caaaacagct gatgatgcta cttctatatc
    95941 aaaagaattt ttcagtgcag taagtgcaaa tattgaatgt ataacagcca ctacataagg
    96001 aaacaaaaat actattccaa tctcaattgt tgaagctttt ttaatctcat tatatgtcat
    96061 acccaattta tttaactgtt catacttttt cttatcaact tggcaatcca tataaaattt
    96121 attatataaa aaactacttg tagtaacaaa gaaaattaaa cctataaata ttgctaaaaa
    96181 tataaatgta gaatacatta atttcccagt tcctatcatt aattctttag agaaaaacaa
    96241 atatggttgc atccctgact cattattaaa tttattttca aattctctgc atatctctat
    96301 agttttactt gaatcctcta cttcaaatgc agtaaatcta tccactataa attttgattc
    96361 tatactatca taaaaattat cctttaccac atacatattt ttgtaatacg ctggcataac
    96421 acattcttcc acttgttttg ccacctttaa acctctattc cctacaataa tattttcttt
    96481 gacgttctta tttcctggta aacttgatga taataatgat atacattcat tatcttcaaa
    96541 acttataggc ttaaccccta tagtttctgt aatttctaag tacttagatt ctttcataat
    96601 tctgacatta aaatcacttt tcttgggaaa tacagtttta aattcaccat taatccttgt
    96661 atagtctaca ttctcttttt ttagattatt ttctataaac atcattcttt ccttgtcttt
    96721 ttctttgcta tcaggctttt tagggtcatt atgcaatgtc attgttgaat aatatattgt
    96781 gttaggatat attaaattaa tttgacgctc tacatctttc caaaaggaat aaactgtacc
    96841 tatagcagta aatgccactg cagaagttat agttatcaag aaaaatattc tagcattatc
    96901 ctttacctta taaatcaagt tcgaaatcca aagcatattt gtattttttc tataaaatct
    96961 cttgtttaat tttagcttct tcataaaaaa tacactaaat tgagaaaaga acaagtaagt
    97021 tgctactata gtaagggatg taactggaac taagcgcaga tatgttgtat attggtcggt
    97081 tgaggtaata gcattataat acgctattat aaacaaacaa atacttaata tagcaagcat
    97141 tagtgatgtt ttaggctctg gttttggagt ttttgtacct ttaagtaact tcaacacctg
    97201 attttcttta actataaaag aagtaaatat tgatgttaat acagctaaaa tcataaaata
    97261 gattaaagta gacaatatcg cattaaatgg tatatagaat tttaatggtg ataattctaa
    97321 aaaagtagac ataaccacta aaaatatctt tgcaaagatt aagcctatta ttattccaat
    97381 tacagaagat actatattta ttatcatatt ttctataaag attaatttca ttacttggcg
    97441 ctttgatata cctgtaatat aaagtattcc aaattcttta tatctacttt taagaaacac
    97501 actaactgaa taaaacacaa agaagaataa gaatagatat gcaattatct tactcatctt
    97561 gagaccttct tttaaataat caggaaattg agatacatct aaatctggat gacttgtaaa
    97621 cataataaaa gaaaatagca gtgaagatga tataacaata cttgctaagt atcctaaata
    97681 cgctttaata tttcttgaaa tattgttaat agcaaactgt tttatattca ttagttatcg
    97741 cctcccaata atgtaagtac atccattatc tcttgataaa actgctctct actactaccc
    97801 ttatatattt cattatatat agacccatct tttatgaata agattctact acagtagctc
    97861 gctgctaatg ggtcatgagt taccatcata gtagtaactt tattttcttt atttatcttt
    97921 tgaaatagct ccattacaac ctttgatgac tttgaatcta aattacctgt tggttcatct
    97981 gctaaaagta ttgatggatt gttaatcaat gctctagcaa tagcagtcct ctgagcttga
    98041 ccacctgata cttcaaaagt tctttttcct aataaatctt ttatacctaa tattgtagat
    98101 acttcattca atctctcatc ttgctctttt acactgacct tatctaatgt caatggcaat
    98161 actatatttt ctcctatagt taatgtatcc aataaattaa aatcctgaaa tacaaaacct
    98221 aactctcttc ttctaaataa tgcaagttcc tcacctctta acaataaagg attcttgccc
    98281 tttaattcca tagttcctgt agttggcttg tcaatagtag aaatcatatt taaaagagta
    98341 gtttttccac taccagatgg acccataatt cctacaaatt ctccatcttc tatactaaaa
    98401 tttatgtcat ttaatgcgtt gaaaattatt tttttaccat atactttact taaattattt
    98461 acagttaaaa ttttcattat ttaactatcc ttcctaattt aatttttgaa ataacatata
    98521 tataattgtt aattataatt tatcttagtt taatttttat agataataaa tctatttttt
    98581 ctatacacta attatgttag taaaagctaa tactgcaagt actacaccca tgattattct
    98641 gtatacagca aacactctca ttggtttttt ctttaaaaaa ttcacgaatt tttccataac
    98701 tattattgat acaataaaag ctactataaa cccaactacc aaagcaatcc acaatgttgg
    98761 tgtcattatt gaataatcaa attcaaataa atcttttcct gaagaagcca ccatagctgg
    98821 tactgctaaa aagaaagaaa actcagctgc tgtaggagaa ttaagtcctg ctatccatcc
    98881 acccataata gtagatgcac tccttgacat acctggccat gcagacaaaa cttgtaatgt
    98941 cccaaccttt aaagcttgta ttggagtaat tttatctata ttatctgtgg aatgattctt
    99001 ttttctaaac aaagtttcta ctactaataa taaaatccca cccactataa atcctataat
    99061 tacagattgt aaattaaaca atgattttat attatcgtaa aatagaactc ctataatcgc
    99121 aaatggtata caacctataa ttacattcat tccaaatcta aaaccaatct ttccttcttt
    99181 tccaccagta aatataaatt taaaaaattc tataacgcta tcttttatct ttttccaata
    99241 aagtactact actgctaata tagccccaag ttgtattaca acctcaaaca tttcagcaaa
    99301 ttgcccctta aaatctatta aattaccaac caaaatcata tgacctgtag atgaaactgg
    99361 aataaattct gtaagcccct ctactatagc tattatgact gatttcaata taaaaataac
    99421 atctaaactc atcaataaac atccttcctt ttttacaaaa tttctttttt tatgttattt
    99481 ctcttatgtt atttcttata ttaattgtaa tttagattag aaaatttaac tatctgcaaa
    99541 cattacacaa accttacatc tatgtaaggt ttgcaaataa actctcttaa attttgatta
    99601 tttaactatg aatatttcat ttaataaatt gtataataaa aaagtacaat taactaaaaa
    99661 ccctattgta acagataatt tacatcttta tcaaactatt tacaccttta ttaaagtaga
    99721 ttgaaacttc tgtacctttt cctacttctg attttatact tactttatga cctaaatcat
    99781 cacatacctt ttttactaga taaagaccca tacctgtaga ttctccaaac ttacgaccat
    99841 tttctcctgt aaaaaatggg gcaaataccc tttttaaatc tttagaaaca attccaattc
    99901 cttcatctat tatacttaaa attacatatt tattattttc ttcagatttt atagttaggt
    99961 agttactata atctttagaa tatttcactc catttgtaat taattgacct attataaatt
   100021 tcatccattt tacatctgta taaacataag taaacttgtc tacttgaatc ttaggaatca
   100081 ttccactttt tataaataac cttttttctt catttacaat actagataca atttcattta
   100141 atttggcttt ttcaactata aagtctttct gaaaattatc tgcccttgca aaatgcatag
   100201 ccatatctaa ccctttattc aatctatcta tttcttttct tatattttca gttacttctt
   100261 ctccctcata atcttggagc tgaaggctta taactgatat tggtgttttc atctgatgaa
   100321 tccattggtt gatgaaagtt aaatgttcac tatgtatctt tttatgctct tgtatcattg
   100381 attgatacaa tttatgttgt tgttttaaaa taactgatat atttctcccc aagaatgagc
   100441 ttcctaaata caaaaatgac tcctccaaag aatgtactcc tttttcaaac agattatata
   100501 cttctctatt tttataatac ttatatatta aaaaacataa caatataaaa gaactaaata
   100561 aaagaatata taaactctct ccaaaactaa taaacttcat aagattacag taaataattg
   100621 tcataactat gcctatataa tatataaaaa tataaccttt ataatctttt aaaaataact
   100681 tcatactttc tccttaccaa ttcttattta atttatatcc taaccctcgg acagtctgaa
   100741 cagcattatc tatacctaat tcctcaaatc ttttccttat cctgctaaca tttacattta
   100801 aagtattttc ctctacaaac tcaatatcat cccatatctt ttctaaaaga taatctctac
   100861 ttactacttt tgggtatctc ttgataagac attcaatcag tataccttct tttttagtta
   100921 taattagatt ctcaccattt aattctagtt ctaacctttc tggataaaat tttaatccat
   100981 ctagctccac tattctttcg tctattttag gtgaatattc accatatacc cttcttatat
   101041 gactctttat ttttgccatt actacatcat agtaaaaagg ttttgttata taatcatctg
   101101 ctccactttc taaagctcta atttggtcta cattaccatc tctagctgat ataaaaatta
   101161 taggtaaatt cgactgttgc ctaatacatc tacaccagta gaaaccatca aatttaggta
   101221 aatttacatc taatagaact aagtgtggct taaaactttc aaatgtaatc attatatcat
   101281 caaagttctc ttcaacaatc acttcaaatc catatttctc aatataatct ttaagtaatg
   101341 tacttattga tatgtcatct tccacaatat atactttata actcatataa ttcctcctaa
   101401 tatacctatt tactcatcat ataacagtcc aattttaata tattataatc tttttacaat
   101461 atataaattt aatcatatta ctaacttcac aattactgac ttcataagta taaccatatt
   101521 attagacatc ttaataaaac tctataaaaa agtatctttt tatgattaat taatcattat
   101581 tatcaactaa tcattctaaa ataaattgaa attactaatt caaaatagaa aaagttacct
   101641 taataaggta acttaaactt ttattatatt tcttacttag tattatttta tcatagtttc
   101701 tacttagcat tatagattaa ttcttttatg ttcacttttt tctcttgtaa cttatttttt
   101761 attaagaagt cttgtgtatc ttcaagcgaa gatatgtctt tatctgttat atctaaacta
   101821 aaatcatacc aagcatataa ttctttagtt tcttcaagac ttaaatcaac ttctttagct
   101881 actttttcca tagcttcatc aaaattatta tttacatatt ctaaagtttc cttttcaacc
   101941 ttcataaatc tttcaactat ttctggatgt ttctctgcaa agtctgtgct aacagcagtt
   102001 actattatac catctactaa accttcacca tttgctacaa gtttactacc tgacttcata
   102061 gctttaagag ctgctggccc agcaatcaat gcagcatcta cgctgccatc agaaagagct
   102121 gctgatgcct ctggaatacc catattaaca aattccacat catccatact taatccttct
   102181 ttatcaagtg ctgaaatcaa tacctgatgt aatatagtcc cttttgggcc tgccaccttc
   102241 ttacctacta aatctgctgc tgattttatt gaattattat tagtcaaaat cataaatcct
   102301 tttggtgacc tgctataagt gtttaatatc tttaactcta ctccattaga tgcagctatt
   102361 aaagctgatg taccacctag tgcatgtaag aagtctattt ctccagcagc taaagcttgt
   102421 gtttgctctg gacctgtagt aatttcgtgg aagttaactt ttatattatc ctttttaaat
   102481 tcctttccaa ataaatcatc ctgtttctga attatagaag gaacatttaa tggtgatttt
   102541 acataagtta aatttatttc tgaaagtttt tctccattat tttttttagc acatccagct
   102601 aaagatgctg ttgcaagtgt taatatcgtt atacctatca atagcttttt taatttcatt
   102661 tactttactc cttaaaatat tattaatttc tttaaatgcc tttatttgac ttcattgtca
   102721 ttaaaatatc tttttttaat ttaatatagt aatctgaagt taaatctcta ttataaccat
   102781 cttctatatt aaattctttt acttttcttt cgtctgtgaa aacaactatt ttcttgccta
   102841 tctttaacgc ttcatcaata tcatgagtta caaatatcac gcctttatta gttgacttat
   102901 gtattcttat aacttcattt tgcatatcaa tccttgtaaa ataatctaat gccgaaaaag
   102961 gctcgtccat aagcaacata tctggattga aagaaagagc tctagctatg cttactctct
   103021 gcgccatacc tcctgacaat tcatttggat aagagttttt aaatttctgc aagttcatca
   103081 tcttaagata tttttctaca tcaatattac ttttcctatt atatttattt gatttgttca
   103141 aattatcatt tgtttctaag cttctaaaat tatcatttat aattttactc ctaattcttt
   103201 tattgtgttt aaattttcta agcaccttgt ttaaaatagt attttttctt tgattatgaa
   103261 aagctatatt ttcacttacg tttaaccaag gcattaatct actctcctga aaaacaaaac
   103321 caacattagg tctatactct ttattatcat taataaacct aatttcacca ctatttatac
   103381 cttcaagtga tgcaattgct ctaagcaagg tagtctttcc acaaccactt tcacctaaaa
   103441 ttactgttat atggtttcta tctatgttta aagagatatc actaagaact acatgttctt
   103501 tattgtcaac tttataactt ttatataaat ttctaattat atatccagag tcacatacta
   103561 aattattcat atgcttccac catctttccc ttacttacct tcttcacaat aatcgaaaat
   103621 atgtaatctg taattattcc taaaagtcca attacgatta tccctacaat aacaacatct
   103681 gttctagaca tttcttttcc atcagatatc aagtatccaa gaccagatga agctgctaca
   103741 agttctgccc caataattgc tctaaagcta tatccaagag ctaactttaa cccaacagca
   103801 atatcaagaa tggcatttgg tattattatt ttaaatatta tctgaagctt tgaaaactca
   103861 aatactctac ccacttcaat cagttttgag tcacaatttt taatcccttt caatgtgctt
   103921 gtaaagattg ggaaaaaaga tgctaaaact ataattataa tttttgattc ctctcctata
   103981 ccaaaccata atataagcat tggtattaaa gcaaggggag gtgtattcct taaaaaattt
   104041 attagagatt taaagtattc gtatactcca ctataaattc caaagaatat ccctaaaggc
   104101 acacctatag cagtacttat tgcaaaacct atcaaaactc ttttcatact tgcatataca
   104161 ttaataaata ttgaaccatc acttatcata tttaaaaatg tactatatac cttttcaggt
   104221 gatggtaata tataatcact ccaaatacca agataatttg taattttcca taataaaaga
   104281 attataaaaa atatcagaac actctttact agccttaaaa acttattatt aaatttattg
   104341 accatttaca aaccatctcc attattacaa ccatctttac aataaaacat ttctactatg
   104401 tcatacttat cttcaaaacc atttcttatt ttttgtattt cacttaatat ttcgtcttca
   104461 cttgatactt caagaacttt ttcaaaagta tctttgaaat atcctaatgg aattggtgat
   104521 tcatctattt ttccaagtga ttttacacct tcttgttcag caaactcttt ccatgtataa
   104581 aacatagcat tacccttatc cttaaacttt tcacttgcaa agtctcttaa ttgtgtacat
   104641 ggacaggtta ctaccaacat atcatcttta ctttttatat atttatcgta taaaacccta
   104701 caagtcctta ctaatattgg ttctatcata ggtacttcaa aattatttat caaattattt
   104761 ctttttaaaa gacttatact ttctggacat ctacaatcca acattgtatt ttcagtcttt
   104821 tttgtatact ctttgtactg cttttttaca tattctaact gtggttcaca ttctgttatt
   104881 atgtacccct tttttatcaa atttgcttta ataaggtgaa acttttctcc atacattctt
   104941 tctgccactg gatttattag aagatattta ttcataacgc ctcctattat ttaatattga
   105001 atattattat caattaatag tttaaatgag cacttaaatt ttgtcaatat attaattttt
   105061 tcttaataaa acaattttta tctacatttt ttaatatttt aaatgaaata ttaaatagta
   105121 tatgtaattt attttaatta ataatgcata catcttacta ataatctatt tatataataa
   105181 tctataaata ttatataata atacttatat aattagtatt attatttaat agcaacagtt
   105241 attcacacta ataaaagtag aaagttttta aaatattatg aaacatcaaa tttaatttta
   105301 aaattgcatc aaaaaatgaa gtctcaacag acttcacttt ttataactct tataaattat
   105361 tcaaaatatt tatacttccc tttctacttc aaaacgtaaa accgtcttca atgattcagg
   105421 cgatactttt ctagcatcac ttatataaat ttcacgatgt gtgtaagatt ttcttataag
   105481 tttatttttt ttgcaaaatt cgttcataat gtcaaagctt tctggttcat tatcatatga
   105541 acctatatga agcatttgaa cacatagccc ttcattaata gacccaaatc taactttttc
   105601 aagaagatta tgaggttttt tcttctttac tatatcagta gctttatcca acaggtcttg
   105661 tgtaacaaaa tctggctgac gtatcattat agtgtaaatt aaatcttctt taataagtac
   105721 atctaagcct ttactttttt ctcccttatc ccatatacct tctaaaggaa aaaccgtata
   105781 gtcaaaatac ccttctggta caattccttt tttaggcatg gtttttattg catatgccaa
   105841 agaataaagt actcctattg cttcagtaaa ttctttagaa tttgggtctc cactcccttt
   105901 taacatgata aatttctgtt ctggtatttc aactattaca ggattctttt taggtaaata
   105961 taactcttta tctctttttc tccattcata tttcataaaa atacctccat atatatttta
   106021 tacattgata ttatcacgct aaaagtgaca acagtgtgtc ataattataa attatattat
   106081 aaaatcttca tcctctaatt cctcatacac tcctttttgg tatccattac ccttagttga
   106141 aaaaaaatca tgtgttttgg tttcagtgct aagaccattt aatacaattg gatttatagc
   106201 atctacagta tatagcttct caaaccctag attttctaaa gctctatttg cattgtattt
   106261 taaaaagttc acaacctctt tttcaagccc actttctctg tatataacat ttgtatactc
   106321 tatctcattc tccataaggc tataaagtat agaatacatc ttctcttcta acatctcctt
   106381 atccatttta tcaaatgaat cgtatatttc ttgtgctagc aatcctatat acttaccatg
   106441 taaagactca tctctaagaa taagcgatat tatttctcca ctagctacca tctttccttg
   106501 accagataga tacaatggat aaaagaatcc tgaataaaac aagaaactct ctaaaaatac
   106561 acttgtaacc attgataggt ataatccctc ttgatttgta gtattttcgt attgagctaa
   106621 aactaaatca gcctttcttt gtaatgttgg ttctgtttct atccattcaa ataattcatc
   106681 tatttctaaa ttagaaagta gagtcataaa tatagaagaa taactttttg catgtatttc
   106741 ttccatagtc cccataaaag acaagacagc ttttctttgt aggttttctg ttaaactcat
   106801 catagatggt attccattat tcccctgttt tgtatccagt aatgttaaac cacccaatac
   106861 ttttttatat aattcctttt ctttattact tagttcattc cataccttta tgtctttaga
   106921 aacagatatt tcttcaggaa gccaaaattg ttttacattt tgttcccaaa aagcttgtgt
   106981 aaatccatct tcttctctat tccagttaac tgcattatgt attttatgta aattaaatgt
   107041 cataatttct ctccctatac tgaacacact agacactcat gagtatctct tgtcatcttt
   107101 gttcttgtgt aatataaact tttcaaacct tttttatagg catatatgta atgtctagct
   107161 atatctctag ttgtcttttc atctgtaaca aacagtgttg ttgatatacc ttggtcaaca
   107221 tggttttgaa ctgttgccac taaatctatg acctttctca tatccatcct gtatgctgat
   107281 tgataataca acatattatc atttgttaaa aatggcattg gatatattgt agtagagtct
   107341 ccatatgttc ttacttctac tggctcagta attggcatta tacttgatgt agcattttga
   107401 acataactaa tgctttgagt tggtgctact gccattaaat atgcattata tatccctttt
   107461 tcttttacct catccaataa ttttgtccag tcttcttttg ttggtatata aatcccttca
   107521 aataatgctc ttaccttttc tgacttaggt agataagatt gttcatagta ttttgataaa
   107581 accttgctat ttcttccctt aacatattct gatttatcaa atccttcaaa agtttgattt
   107641 ctttctatag ctattttcat agaagcttta attgaatagt atctaaccat tgcaaaaaat
   107701 acattagaaa aatctatagc atcatctgaa gtatataaaa tattttctct tactaagtat
   107761 ccatgtaaat tcatagctcc taatcctata gaatgagact tgctgttact attgcttacc
   107821 gttggcactg gttttatatc tgtgctatct gctacaaatg acagtgctct tattgctgtt
   107881 tcaactgtac tttctatagt tttattatcc attacattag ctatgtttaa agaacctagg
   107941 ttacaactta tatcttgtcc ccattcattt tttcctccat acccctctat ttctgaaggt
   108001 gtttgatatt gaaatatctc acaacataag ttagacattt taataattcc aacatctttt
   108061 aatgtatgtt ctctattagc tgtatctatg tacactacat atggatatcc actttcttgt
   108121 tgcatctgtg ctatttttgt caacatctgc ctaggattta tttctttttt tcttatatca
   108181 ctatcattaa ccaatttatc ataccactca tccatttcta tctcatcaag agaaactcca
   108241 tatttcttat acacagtatg aggataaaat gcatatgcta cttcattttt ttctgccaac
   108301 tccataaatt tatctggtat tatagctcct aatgataatg tagcaagcct tattttttca
   108361 tctgcattta tctttttagt atccatcaac aattcaaaat caggatggaa tacagtaagg
   108421 tacaccgcac cagaaccttg tctagctccc atttgattaa agtaactaaa tgattgttct
   108481 aacattttag ctactccaac aacacctcca gctgcacctt ctatatcttt gatagattcg
   108541 ccagatgctc taagtttaga taaatttagt gcaactcctc caccaatctt tgataagtga
   108601 tttgatgaag atatagcata tgatatacct tctgtactat cttctacaga tagtaaaaaa
   108661 catgatacca tttctccagc cctttttctt ccagcattta aaaaagtagg tgtagctggt
   108721 tgaaattctt gttttactat tttatctgcc aagtttaaag ctaaatcttt atcaccattt
   108781 cctagtgtca aagctacaat taacacttta tcattatatg tttctaatat ttcctttcca
   108841 tcattgctct ttaatgcata attttgataa aacttatttg cactcatata tgattgaaat
   108901 tcaaacttat gtttatcaat catatcatat atatttttaa taacatctat gctatactga
   108961 tttattactt cttttgaata ataaccttca tctattaaat acttcaatct ttcttctagg
   109021 ttattaaatt ttctcaactt tggctgtata aattcttcta tgtaactact taaggcttcc
   109081 ttatcctttt ccaattggta cttgccttgt tcatttttaa ttatcacttg attgttaagc
   109141 tctatccaat tcattattta ccgtcctttt aacataatct tgtgccataa tttcacttaa
   109201 tttgcttatt atttcttttg gtacttatca gttgaaatcc caaaattaat ctataattat
   109261 agaaatgcaa taagtatttt tcaaaaacaa aagcactaca tatagtcagt gctttatcta
   109321 ttatatacta catatagtat atacacaaat ttttttatat ctaaactttt attactttat
   109381 aattgacatt atttttattt aaagaaa
//
LOCUS       DAEPHU010000002       107892 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 01A10CD0081
            SAMN05941466-rid12468953.denovo.002, whole genome shotgun sequence.
ACCESSION   DAEPHU010000002 DAEPHU010000000
VERSION     DAEPHU010000002.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941466
            Sequence Read Archive: SRR6291087
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 107892)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 107892)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068158.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 22:43:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,892
            CDSs (total)                      :: 3,805
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 87
            rRNAs                             :: 8, 1, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 55
            CDSs (without protein)            :: 55
            Pseudo Genes (ambiguous residues) :: 0 of 55
            Pseudo Genes (frameshifted)       :: 21 of 55
            Pseudo Genes (incomplete)         :: 28 of 55
            Pseudo Genes (internal stop)      :: 16 of 55
            Pseudo Genes (multiple problems)  :: 8 of 55
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..107892
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941466-rid12468953.denovo.002"
                     /strain="01A10CD0081"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            <1..770
                     /locus_tag="KR231_000094"
     CDS             <1..770
                     /locus_tag="KR231_000094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="M15 family metallopeptidase"
                     /protein_id="HBH0002514.1"
                     /translation="KRRKINKLKLTIVITVLFLALLSIYEILFSNPNKKGNIKSQETM
                     QNKNNTTDDSKNNQSSTKKQEDNNIKPTFSYSSIPDNIKNKMIGKSMPTDEPISFDSL
                     SYLKLTYYGFDEKTHQGEMIVNSELAPEVVDIFKELYEKKYPIEKIKLIDDYDAVDEK
                     SMSDNNTSSFCYRTIAGTNVVSNHGKGRAIDINPLQNPQVSGNDVTPKVSTVYADRSS
                     TKFGMIKKGDDCYNAFVSRGWSWGGYWKNPDYQHFEK"
     gene            796..2715
                     /locus_tag="KR231_000095"
     CDS             796..2715
                     /locus_tag="KR231_000095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_071223118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HBH0002515.1"
                     /translation="MNLMTLENISKSYSEKKLLENISLGINEGEKIGLIGVNGTGKST
                     LLKIIAGVEESETGNITKTNGIRIEYLPQNPTYNENSTVLEQVFNGTSEELKLLGEYQ
                     EILEKLNSNFTEELNKKLLSVHEKIDALNLWDLESEAKSVLTKLGINDFNQKIAELSG
                     GQRKRVSLASALITPCEFLILDEPTNHLDNDTIDWLEEYLNSRKGSLLMITHDRYFLD
                     RVTNRIIELDKGRLFSYDGNYSIFLEKKMERLSLEASIEDKRQNLIRTELAWVRRGAQ
                     ARSTKQKARLQRFDELINRDSFKPDENLDISVASSRLGNKIIEIHNISKSFEENTVID
                     NLEYTLTRTDRIGIIGKNGMGKSTLINILNGEIEPDSGYISIGETVKIGCFSQDDSHM
                     NIDMRAIDYVKEASDYIETSDGTRITASQMCERFLFNGTMQYTLIGKLSGGERRRLHL
                     LKILMTAPNVLLLDEPTNDLDIETLKILEEYLDEFKGVVVTVSHDRYFLDRICNKIFA
                     YEGNGKIHIYTGNYSDYLIYREIQGIEFEESKKESVKKDDSTTLKKEKPKNDKKLKFS
                     YNEQREFENIDSDIEKLESKIATLDESTAKFSTDFTKLQEILDEKSKLEKELEYKYER
                     WEYLNNLADEIANNK"
     gene            complement(2957..3304)
                     /locus_tag="KR231_000096"
     CDS             complement(2957..3304)
                     /locus_tag="KR231_000096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PqqD family protein"
                     /protein_id="HBH0002516.1"
                     /translation="MSKSNDVLDIVFKITDGLEYEVAENRVVTILEKQDHKIQKFFRK
                     LKARIPKYKKIELDEYSSFVFLQIDGQRTVREIGKNLEAKYGEESHPLYERLLVFLNH
                     IEVNCHYIERLDI"
     gene            complement(3291..5219)
                     /locus_tag="KR231_000097"
     CDS             complement(3291..5219)
                     /locus_tag="KR231_000097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligopeptide transporter, OPT family"
                     /protein_id="HBH0002517.1"
                     /translation="MNKKLPKGAYGEVSGKDYVPYITDKSRTGGNVAVLIIGIILAAI
                     FAASTTYSGMKAGLTVAAGIPGAIIGSAFVGAFARSKGILGKNLIQGMSSGGESVASG
                     FIFVLPAVILIGSQITFFEGLAVGVGGVLFGIGIAAIVHNYLIVEEHGKLMYPESMAI
                     SETLVASEAGGDSIKYMGIGFVISGFITVLTGSFLNVANNVMSLVGSKFYKWKFDIEV
                     NPLLLGIGFIVGLEVSLTMFAGSILSNFGIAPLIGYFTDMAKDGAMVWNNPAMPLNQM
                     DVGAISSSYVKYIGAGMMLCGGIIGAIKLIPTIIASIKETLKAKSSAGEGEEGSSIQM
                     ILLLGGVVIGFLAAFLISGNIVMAIIGAIISLLLSLLFVIVAGRLTGTIGTSNLPVSG
                     MTIASLVIVTLVFVIMGWTDLEANKSLLLFGSFIVVAIAIAGGYTQSQKVTYIIGGSK
                     NEMQRYFTIASIVGVIVVVGVILLLSDQLRATGDNVQFALPQANLMSTLTSGIMSGSL
                     PWVMIIVGVFMAIVLYALNLPIMTIAIGFYLPIATTSIILVGALIRLFVELVSKTEKE
                     KEVKVSNGISLSSGLVAGGSIIGLIGIILQVTGVVTPKVPSGFAATNSMAIALLVVLV
                     VLTALPIVLSKVKNNEQE"
     gene            complement(5630..7819)
                     /locus_tag="KR231_000098"
     CDS             complement(5630..7819)
                     /locus_tag="KR231_000098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid adenylation domain-containing
                     protein"
                     /protein_id="HBH0002518.1"
                     /translation="MYEVNLERAMNYWMDLLDDYTNIAKITNDFFYKDCSDEVVDEVF
                     KMNIEKHERLIQYSKVNNISIDSIIETIYGLILQKYIYEDDVVFGKTMNIIPIRVRVR
                     QSEKFIDVVRKLKRQWSRSLEYGYYLLSDIENKNHLNTKLINTIFIAKSFDLSYDYDI
                     EKKGYDLSVIVYTKRALKIKIKYKPSIYKRETIRRILNQFDYIIEQIIEDNDILIEDL
                     EFVCKEEEKVLLEDFNNNQYEIPYDKSYVDLFREQVKVTPSNIAARDENRKLTYKELD
                     EVTDKLAGYLNHIGVESEDIVAVMLPRDINIIITAIGIMKSGGAFFPIDTSNPEERLN
                     YLLEDSNAKVVITTDELKSKVVNENTIVLDINDEEMFKLGYELTEKITSSNCAYTIST
                     SGSTGRPKTIAIEHKSLVNMCYYSVKSISATENDICGIYLSFSFDAVMKQLFPYLLVG
                     ASIDIMPEEAKFDEYTVNEYCEENDITILALPTAFARLFIQNCNNNSLRVVQTGGERL
                     KGYRKRNYELYNEYGPTEFTVVSTSFHVDREYGKIPIGKPIFNTYAYVLDKKNKLCPI
                     GAPGELCLSGIQISRGYLNKKGLTEQVFVENPYKTCEHNKLMYRTGDLVRWLDDGNLD
                     YIGRMDNQVKIDEFRIELYEIENIINNITEIKSVVCISRTNDDGDMYICAYYVIDEED
                     SGKINERTIREYLNEHLPPYMIPTIIMRIDKIPVTPIGKVNKRALPE"
     gene            8150..8881
                     /locus_tag="KR231_000099"
     CDS             8150..8881
                     /locus_tag="KR231_000099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerophosphodiester phosphodiesterase"
                     /protein_id="HBH0002519.1"
                     /translation="MNIYAHRGFSGKYPENTILAFKKCLDMDIYGIELDVHRTKDGKI
                     VVIHDEKVDRTFNGHGFVKDFTLRKLKTLNSSFEGYQSNKECKIPTLEEVLILISPTD
                     LILNIELKTDKINYPNIEKDVLELILKYNMKNRVLISSFNSNSLKNFHKLDPSIKTGL
                     LCYLPINNVVNFAKFLGNSYLHPPLVLVNESLIELCHKNLLGVNVYTVNEEGDILHCL
                     KLNVDGIFTNYPDIASNLLHSKQYS"
     gene            8961..9596
                     /locus_tag="KR231_000100"
     CDS             8961..9596
                     /locus_tag="KR231_000100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HBH0002520.1"
                     /translation="MDNLLNELEALKSNLDNLPIEKIENYDLSKTALFIIDVNNGFAR
                     QGALYSPRVESLIKPIEMFTKKISNKLNRVIAFTDSHTPKSIELLSYPVHCLENDVES
                     ELVDELKSIENLQILPKNSTNGFFALENLDFDNIDNIIIVGDCTDICIYQFAITLKSY
                     FNQHNIEKNIVVPMNLVDTYDIPNVHPAEILNLVFFNSMIQNGVNVLKEIR"
     gene            complement(9847..10440)
                     /locus_tag="KR231_000101"
     CDS             complement(9847..10440)
                     /locus_tag="KR231_000101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3867 domain-containing protein"
                     /protein_id="HBH0002521.1"
                     /translation="MSDDRIIDFNELKNKVKDSDVDKFEQYIYNLYFSVMDGKMSMAE
                     FSRKIFDYMRDNNISQEKFMKIQKQFMERYGMDTEEVEKQLRNFGIDPSTAGFMSNNT
                     SSKVSTEDLESFKKSAGFYEKYGEKIQPKSCITTFIKNDLNDINVIIDQEKIMLCSDR
                     KINLMDSELNEFLLEYKNMFNKKIKVVMCETTNKYDY"
     gene            complement(10511..11374)
                     /locus_tag="KR231_000102"
     CDS             complement(10511..11374)
                     /locus_tag="KR231_000102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LD-carboxypeptidase"
                     /protein_id="HBH0002522.1"
                     /translation="MLGIIAPSGPLRNTSLEEIKFNLESYGYEVKFSESCSLNYKGYL
                     AGNDDIRARDIEDMFLDKDVDIIMCLRGGYGTTRILDKINYDIIKQNPKPFIGFSDIT
                     GLNLAFYKNCGLLPYHGIMAANVGKWGKFTYKSLVNALEFKDELYLENPKEEKIYTVC
                     EGKAEGIIMGGNLSLIIATMGTKYEIDAKDKILFIEEIGEPQYKLDRMLTQLYSSGKL
                     EECNGIIFGDFKDCIEENDLMELLIEFANKVNKPSIYNLQSGHCIPMITIPLGRMCEL
                     DATEKIVKLKK"
     gene            11537..12706
                     /locus_tag="KR231_000103"
     CDS             11537..12706
                     /locus_tag="KR231_000103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HBH0002523.1"
                     /translation="MLNIKTLCHEINDWVINIRRDLHKTPELGLEEFQTKKKIIKYLN
                     EIGINYIEYKNHTGITAYINVSPNFETVAIRADIDALPITEELNYSYKSINIGKMHAC
                     GHDAHTAILLGTCNILFKLKDYLNVNVKFFFQPAEETIGGAQLMIEDGCLEKPNVKYI
                     FGLHVNPNINKNLIELKYNTLNASTNTLQLTVHGSKCHGAYPHQGIDAIVISAHIITA
                     LQTIVSRNTNPTDSVVISLGKIEGGIKENIVCDKVVIRGTLRTLTPETREFSKKRIRE
                     ICDFTCKTFGGSISVEIEEGYPALINSNHLVDYVKQNAVELFGEENIILKDSPTLGAE
                     DFSYFLRHCEGAFYHLGCANREKNITSPLHTSTFDIDEDCLITGVMLHVKNVLSF"
     gene            12807..13283
                     /locus_tag="KR231_000104"
     CDS             12807..13283
                     /locus_tag="KR231_000104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAM-dependent methyltransferase"
                     /protein_id="HBH0002524.1"
                     /translation="MKEILINPIGKICIQGEEVFIKLDKKYVPALNELDDFSHLNVFW
                     WADGFDNPELRSILETPKPYKSGPDVIGIFATRSPIRPNPIALTAVQIINIDHENGII
                     KIPYIDANDNSPVIDLKPYTPSVDRVENPSVPKWCSHWPKSVEKSGEFNWEDEIEF"
     gene            13849..14643
                     /locus_tag="KR231_000105"
     CDS             13849..14643
                     /locus_tag="KR231_000105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M55 family metallopeptidase"
                     /protein_id="HBH0002525.1"
                     /translation="MKLYLSADIEGTCGIVNWDETKLECEFSQHYRTQMSKEITAACD
                     GATQSGVHEILVKDAHDSGRNINPNILPENVKILRGWTKDPLVMMAGIDESFDACIFT
                     GYHSGATCNGNPLSHTMDIDYDYFKINDEIASEFTINAYIAAYYNVPVAFLSGDEMLC
                     ESAKKLNPNIVTVPVSKGIGNGSISIHPNLALKKIEKGVKKALSGDLSRHLIKLPDKF
                     KIEIKFREHYKAFKASFYPNMKKIDSQTVLFETEDYYEFLRMLLFI"
     gene            14667..15110
                     /locus_tag="KR231_000106"
     CDS             14667..15110
                     /locus_tag="KR231_000106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438483.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="regulatory YrvL family protein"
                     /protein_id="HBH0002526.1"
                     /translation="MIKISNKRRIPLGEFISVFLFFAVFFGITFCIFTVIGIGFLSFL
                     GFEYKSLGAVLIFFLIYFCITTPIDFLCTTILDIFRYVNKLPYSIYKLCEFIIDFILT
                     FLAMNIIDTFMDSVTIPLSTEILFALLSYLLSECMDFFDRDKKKP"
     gene            complement(15199..16485)
                     /locus_tag="KR231_000107"
     CDS             complement(15199..16485)
                     /locus_tag="KR231_000107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HBH0002527.1"
                     /translation="MEKVKVAVIGAGNRGTYAYAPYIYENSDVCEIVAVAEPKKGRRE
                     LFTQKYNLDSKNVFETLEDFFKHDKMADAVIIATNDDRHYDVAKLALEKGYHVLLEKP
                     MSNSLDGLVHIDDLCDKYKDKIFMICHVLRYSPFYNKLKEIVESKKLGELVSIQYNEN
                     IGYWHFAHSFTRGNWRNSNETSPLILAKSCHDMDILLYLVGSRCKKISAFGSLKHLNN
                     QNASGEMAQNCLQCLVEKKCPYSAKRIYLEKDRSINRAVHINPTEENLLNILKTSPYG
                     RCVYRCDNNVVDNMVNILQFENGVTATFNLCAFTKENGRTIKLMFSHGEVGGDLNKNE
                     IRIKEFGKNEEIVMNPSNQQNMVEEYDRNLIAEFIKLVSNKELEKGRVAAKEAIQSHV
                     MAFAAEYSRVSDEVVYIEEFFDSAKQMTKEIEETIF"
     gene            complement(16703..17593)
                     /locus_tag="KR231_000108"
     CDS             complement(16703..17593)
                     /locus_tag="KR231_000108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DMT family transporter"
                     /protein_id="HBH0002528.1"
                     /translation="MSSTIKSNRIKGIMFIIASALGFAMMSAFVKLAGDLPSFQKVFF
                     RNLVSAIIAFWLIIKHKGSLTGKKENLKVLLYRSIFGTLGVIFNYYAIDKLMLSDANM
                     LNKMSPFLVVIFCAIALKEKINVKQIGAIIIAFIGALFIIKPTFSVEVIPYLGGIAGA
                     VFAAMAYTCLRVLGDREDYYTIVFFFSVFSLVTVGPIAFAVYEPMTLMQLIYLLLGGV
                     FASLGQFGITLAYKYAPAKEISIFDYSNIIFSAILSIFLFNVYPDMLSVVGYLIVFSA
                     AFYMFLYNKKLDKLDKEKKK"
     gene            17885..18229
                     /locus_tag="KR231_000109"
     CDS             17885..18229
                     /locus_tag="KR231_000109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RidA family protein"
                     /protein_id="HBH0002529.1"
                     /translation="MEIKRYEGTGRMSRAVVHNNTVYLCGQTHAEGGVIEQTTEVLAK
                     IEDLLNKYGSDKQHLLSVTIYLRDMKDFEAMNSVWDAWVEKGFEPARACVEARLAREH
                     LLVEMSVVAATK"
     gene            complement(18388..20484)
                     /locus_tag="KR231_000110"
     CDS             complement(18388..20484)
                     /locus_tag="KR231_000110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CocE/NonD family hydrolase"
                     /protein_id="HBH0002530.1"
                     /translation="MIKFKLYISGLYSGNVIFDGDLLIEKLNPFTNKIESLKPISKEE
                     NTYYLNLTKIDLKSLFNNFDVYTKSLVNTDKDTVINNLGETHSKLNEYIWVQRNKKFP
                     LDIIIVDNKIVGFICLSRETCTILIMDGYEEYTVLKEWEKTHKNEEIYSIRFGGNYMI
                     DMKDGIKLSTDVYLPDFVDSAKKAPTILMRTPYGKENDKEIYYKYVQRGYAVVIQDVR
                     GRNESEGKWEPMIHEREDGDSTINWIVSQEWSSGIVGMLGASYLGYVQWAAASSGNKH
                     LKALVSIVTSGSPFIDIPRKGGAFVSGMLAWAFMVSRNKVDRSKMVRDDWDDVLNIRP
                     IENIPVEALGYRIEFLEEWLKRVEKDEYWDLMDWHLQKDKINVPALVVSGWYDDNSMG
                     TTEALDVIKDYEKGKRKAILGPWMHNSNTLRDINGISLGNSSLRYDLDYNYLLWFDKY
                     LKGIENNIDTTAPVEYYSVGSNKWKTEENWPIINKIDKSMYLISDGNANTSLGNGRLV
                     FDNDLEEKYDSYIYNPKDPSVQLIDMSENEVGVPNNYKDLEKRSDMLCYTSDAFSEEF
                     TVTGDIKLEFFASSSAKDTDWVIKIMDVDLDGNSIKLADGILSARFRNSFYKSEFMEE
                     GEIYKFTIITSKISNTFKVGHKIRLDITSSAKNFIFQNSNTTEGYNSIEYIEAKNTIY
                     HGGKYPSKLILPIENK"
     gene            complement(20497..21657)
                     /locus_tag="KR231_000111"
     CDS             complement(20497..21657)
                     /locus_tag="KR231_000111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF819 family protein"
                     /protein_id="HBH0002531.1"
                     /translation="MNTLFSNPGSILAVMTSMIALGFYLQRYKAIKSLGPALTIIIMG
                     IILSNLKVVPVSTELYGTISTYAIPISMTIMLMSVDLKEMTKLSREPLIAIFVAVLTV
                     SIMAFLFGLVFAEKISEGWKVAGMFVGTYTGGSANLTAIGTGLNVSRQTLAAANAADY
                     VIGVPTLIFMFALPAILKNSKKFKKLWPYHVEESELEDCQNEEFMESKEWSIKDIAWM
                     LAIGFVVTEVSTILAGYFNSSFSSAARILLVTTISIIIAQLKPVKKLKGNLDLGLFVA
                     LFFLCTIGFSVDIKEFLGSTFTITLYCFSIIFASFVFHLGITRLLKIKYQYVILSIVG
                     AIADGPTSALVAASAKWNSLVSVAVVMGVIGGVLGNYAGISVAYAIKMSLGL"
     gene            complement(21676..22743)
                     /locus_tag="KR231_000112"
     CDS             complement(21676..22743)
                     /locus_tag="KR231_000112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptide epimerase"
                     /protein_id="HBH0002532.1"
                     /translation="MKITDIKFEKLRIKLKKPVVVSFGVIEYGESIILKIETDEGYCG
                     FGEAAPLAAVTGEVLDNVLSVLLMFKKELIGKDPLDIETIHTIMDGIIIGNTSAKAAI
                     DIALYDIKGKIMNAPLYKVLGGFDSKVQTDITISIDKPEKMAVEALERVKEGFRILKL
                     KAGINPEDDIEAVKLIREAVGESIRIRIDANQGWNVNSSINTIKKLEEFNVDAIEQAL
                     PHWDLDGTAYIRNKSNTKIMIDESLHSPIDAIKAIKKNAVDTFNIKLMKSSGIYPAIK
                     INNIAEASGVNCMLGCMLETRIGITAAANLIASKKNITEADLDSFMFCEELEGISGGF
                     VMDGDIMNLVNKPGLGIEVNL"
     gene            23095..23661
                     /locus_tag="KR231_000113"
     CDS             23095..23661
                     /locus_tag="KR231_000113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBH0002533.1"
                     /translation="MLGEKMRNIRKSKKKTLSDVSKLTDLSISYISQIERDAIEPSLS
                     SLRKIAEVLDTPLYMFMDDNNTDDLVIRKEDRVMMKFPKSEMFYEIVSPMPTTEFTPS
                     ILFVEFELKPESEDAKDYIYHASEEIMVVTSGVVDICMGEKVVRLNPGDSTFIKANVP
                     HKIINPSKDTIARGYGVISPPIWPIKSK"
     gene            complement(23856..24842)
                     /locus_tag="KR231_000114"
     CDS             complement(23856..24842)
                     /locus_tag="KR231_000114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin-dependent carboxyltransferase"
                     /protein_id="HBH0002534.1"
                     /translation="MGFKVELGGFQTLIQDRGRVGYGQYGVSGCGAMDEYAHRVGNIL
                     VGNSEDEASLEVLMLGPTITFDEYTQIAVTGGDLGAKINGKEIQNWRSYQINPGDVLS
                     FRGVKSGARAYVSIAGGIDVPLAMGSKSTYTRAKIGGFEGRALKKGDYINTFIQEKDF
                     TINKKLSSKYIPTYSSEIVLRIVKGPQFDAFSNGEVEKFLSNKYKVTNEIDRMGCRLD
                     GESIKHLNGADIISDGISYGAIQVPGHGKPIIMLSDRQTSGGYTKIGNVISVDLYKLA
                     QAKPNDVVKFELVDIYEAHRLLREQEDKIQDIYKSMKNIRVVKAKVLNDIAV"
     gene            complement(24872..25567)
                     /gene="pxpB"
                     /locus_tag="KR231_000115"
     CDS             complement(24872..25567)
                     /gene="pxpB"
                     /locus_tag="KR231_000115"
                     /EC_number="3.5.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-oxoprolinase subunit PxpB"
                     /protein_id="HBH0002535.1"
                     /translation="METRYLISGDKAVVAEFGNEISEDINKKVISFMRAIEISNLKGI
                     VTEMVPTYRSLMISYNPLEIDFDSLIENLKKIEDNLESIVLPKPKIHEIPVCYDEVFG
                     IDIKNVASYNNLTVDEVIKIHTSREYLIYMLGFTPGFPYLGGMDERIATPRLEVPRTK
                     IYGGSVGIAGSQTGVYPIDSPGGWQIIGRTPLKLYDENREEQILLRAGDFIKFVPITL
                     DEFIEIEKNNLSI"
     gene            complement(25587..26807)
                     /locus_tag="KR231_000116"
     CDS             complement(25587..26807)
                     /locus_tag="KR231_000116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="divalent metal cation transporter"
                     /protein_id="HBH0002536.1"
                     /translation="MSTKNITDKTKNKKDVGALIGAAFIMATSAIGPGFLTQTAQFTQ
                     DFGPNFSFVILITTILFIGAQVNVWRVIGVSGLRGQDIANKIIPGLGYLVAFLVALGG
                     LAFNIGNVGGAALGMNVMFNMNMTLGTVLSGLIAIFVFMSKNSNSLVDKITKFLALGM
                     IIIVGYVAISNHPPVGEAVSRMVKPENPKGLIFPIITLLGGSVGGYITFAGGHRLIDG
                     GITGEENIKEITKSSLLGILVATMMRVLLFLAILAVVSKGLQLDPENPAASAFKFSAG
                     AIGYKFFGLVLWSAAITSVIGAAYTSVSFLKTLNPFIDKYEKYFIIAFIAISTLIMAF
                     IGKPATLLILAGALNGLILPITLGIMLIASKRKDIVGDYKHPTWLLIFGLIVVLISAY
                     TGITSLSSLGALFA"
     gene            complement(26836..27627)
                     /locus_tag="KR231_000117"
     CDS             complement(26836..27627)
                     /locus_tag="KR231_000117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LamB/YcsF family protein"
                     /protein_id="HBH0002537.1"
                     /translation="MYKVDLNSDLGESFGTYKIGLDEEVLKYISSANIACGFHAGDPS
                     HMEKTVQLAKKNGVKIGAHPGFLDLIGFGRREMKITKQEAKDYTKYQLGALMAFASSN
                     GCNIQHVKPHGALYNMAAKDKELAMGICEAIYEVDKDIILLGLYNSEMINSAKEIGLR
                     FANEVFADRAYDNNGFLVPRNVEGAVIHDTKHAIDRVVRMVKEGTVETLTGEVIHIKA
                     DSICVHGDNPKAIEFVKEIRKRFELESIEVCPLENIEVCSSENIV"
     gene            28215..28844
                     /locus_tag="KR231_000118"
     CDS             28215..28844
                     /locus_tag="KR231_000118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBH0002538.1"
                     /translation="MDKNYTMPIYQKIALDIANKIYTGEIQEDSVLFGRSVLAGKYNV
                     SPETIRRSVKILEDIGVVKSIKGKGVIVLSPDKASSFIKKYRDITNISSYKSTLYNLI
                     DTKSNLENEILDTINKILDYSNRLEIINPLVPVQFTINSNCKYIGQTAAQTKFWQNTG
                     ATIVAIKRGEELIISPGPYIEFLEGDILLVVGDQHIYNSIPMFLYENEK"
     gene            complement(28958..30472)
                     /gene="glpK"
                     /locus_tag="KR231_000119"
     CDS             complement(28958..30472)
                     /gene="glpK"
                     /locus_tag="KR231_000119"
                     /EC_number="2.7.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol kinase GlpK"
                     /protein_id="HBH0002539.1"
                     /translation="MEKKYVMALDQGTTSSRAILFNKKGEIVKIAQKEFNQIYPKAGW
                     VEHDPMEIWGSQSGVMREVIETAGIRPEEIASIGITNQRETTVVWSRYTGKPIYNAIV
                     WQCRRTSEICDELKNKGLEESIKEKTGLLIDAYFSATKVKWILDNVEGAREKAEQGEL
                     LFGTIDTWLIWNLTRGKVHVTDYSNASRTMMYNINDLEWDEDILRELDIPISMLPLVK
                     PSSYVYGHTDERMLSGAKIPIAGCAGDQQAALFGQNCVEEGTAKNTYGTGCFLLMNTG
                     SNIVKSKHGLLTTIAWGVDGKVTYALEGSIFIGGASVQWLRDELKIIESAKDSEMYAN
                     RVEDTNGVYVVPAFTGLGAPYWDMYARGSILGLTRGAKKEHIVRATLESIAYQTKDVL
                     EAMQNDSKLKLKSLKVDGGASNNNFLMQFQSDILNVDIDRPKIVETTALGAAYLAGLS
                     VGFYIGRNEITSKWSVEKEFNPNMSEEKRCKLYKGWKKAVSRALSWEKEDELDI"
     gene            30716..31258
                     /locus_tag="KR231_000120"
     CDS             30716..31258
                     /locus_tag="KR231_000120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBH0002540.1"
                     /translation="MPKILENVKEDILKVSRDMILEEDYSNISIRKIAQRCGISAGTV
                     YNYFNSKQEIIEYITKSEWDLLIRRIEYSNKNTEDYIKKLNIIFTEIRNFINKVHNIQ
                     YNDFLNTFETERFFEMKKHKDDFHEQLSNKVYEALEKESFFNNDKLVCNIIIKMFFSY
                     STYLHIEFEDLKPYIEKLIH"
     gene            31272..33764
                     /locus_tag="KR231_000121"
     CDS             31272..33764
                     /locus_tag="KR231_000121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBH0002541.1"
                     /translation="MNHNTSIKNKDSNPKIFLVLTLYLLGIFMGAIDTGIVSPARTII
                     QNSLGVNEKTGIWMITIYTLTYASVIPISGKLADKIGRKYVYLVSIFLFGSGSLICGL
                     SSLFSNFYILLIGRVIQAIGGGGIMPIATAEFGTTFPENKRGMALGLVGATYGIANIL
                     GSSIGSTILSIFGTQNWKWLFFVNLPICLIILIGGVFCIKNNKSESKEKIDKLGTLML
                     ICIIVSLLYGLMNIDFFNFKNSIQDISVYPYLLTFIVLIPIFIFIENRAKDPILSFEY
                     FLNPRILIVLILSLIVGIGMMGMVFVPQYAENALKINAGSGGYFVAILGLFAGIAAPL
                     SGRLIDKFGAKKILLLGFSVSMIGSLYLVLIALKTNTVFSVCVSLIFMGLGMGFTMGT
                     PLNYMMLSNTRLEESNSALATLSLIRSIGTSISPAIMIGFIAHAGLSVQDNIMDLVGK
                     PSTPKIVQLEELENMIDDLKSDPEMAKNLKNVSIPNMNDTSNINMDMTGGKLPKSLLN
                     KVQSADTTNITNITKEISTTMFDEKVPSIITKIQKNVQKGIDGTQSGINGIEDGENKL
                     NSGIKGVQTGIDNMVKARAGINQGIDGVKKGIAGVDKGIKGMEQGLEKQDEAIKELTT
                     AYNKIPTTEKTPTDNENNSNEQNQSNTSNSESDDTKNDSTENKNNNSSENKPNVNEQK
                     ESLNAQIQQLKKTRDDLNTKLQKNKTQKNELSKKLRSMESQKKELQSKLNNSISQKKD
                     MEKSLDTMQQQKKSLQAVLAKTQEVKTEIPKAFDKSKLDYINSIENNRTKIENTLQST
                     LNSGFKQMYITVFCVNLLAFIILLFYKENKTR"
     gene            34185..34583
                     /locus_tag="KR231_000122"
     CDS             34185..34583
                     /locus_tag="KR231_000122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBH0002542.1"
                     /translation="MDTLGKRIAYLRNSKKLTQRKLMDILKFENLGKYETGDRKPNCD
                     ILMSIADYFNVTTDWLLYGKEKVNVNSSVKEDKEDYLHVTNDEMTILNLYRQLNERDK
                     IKIEGILELKISEYKDLKKHSSNNNEDKMV"
     gene            complement(34800..35009)
                     /locus_tag="KR231_000123"
     CDS             complement(34800..35009)
                     /locus_tag="KR231_000123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0002543.1"
                     /translation="MCKLDSDGVIECCRAIDDFITALSNIKSLNMERLNTLTKYSSTC
                     SILLKEGNYEGCTIVYRKMLEELKT"
     gene            complement(35041..35250)
                     /locus_tag="KR231_000124"
     CDS             complement(35041..35250)
                     /locus_tag="KR231_000124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBH0002544.1"
                     /translation="MDARKKWIPFLGVQVKQRLIELNMTQRELAKKIGVNENYLSAIL
                     NGRRTGKKYKSSIYQLLNIEYSEDD"
     gene            35549..35968
                     /locus_tag="KR231_000125"
     CDS             35549..35968
                     /locus_tag="KR231_000125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBH0002545.1"
                     /translation="MDTLGERIVYLRKAKNLKQYELEEMLGCDNLSKFERNIRKPNYE
                     ILKSIAEIFNVSVDWLLNGDNLSHKSDLICDSSSNYPLNSINSNEIKLLNNFRKLNDY
                     DKAKIEGMIELKLHEYEKEKDLGKIEYNKNKDEKIDK"
     gene            36196..36651
                     /locus_tag="KR231_000126"
     CDS             36196..36651
                     /locus_tag="KR231_000126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419674.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0002546.1"
                     /translation="MGLRDKFAQSFARSKTMSGPEKKANEIMGKLLLKKAILPIVLMF
                     VIIIAGAMLKINSWVTLGINLVIAVGAFFYIRNSSKKYQNFKPYVGNLISLEKKGKKE
                     YVAIIKQGKLPVKLQIAYGGEDLEHVKKNQMVQISYNPDAKIAILVNRQ"
     gene            complement(36858..37118)
                     /locus_tag="KR231_000127"
     CDS             complement(36858..37118)
                     /locus_tag="KR231_000127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438465.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0002547.1"
                     /translation="MDKLITELSSLGAIGILCALLFKNTMQEKKEDRDMYKKTVENFI
                     ELSTQQQEINKNILVQMGIMKTDVEEIKEDVTDIKGMLQNGV"
     gene            complement(37381..37734)
                     /locus_tag="KR231_000128"
     CDS             complement(37381..37734)
                     /locus_tag="KR231_000128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0002548.1"
                     /translation="MFKFDKNKIEQIKQGRKVEMQYKDISDISIGQVKQDDDITNNFI
                     ANVEIYEMLLNQSSVNEASNISTFSVRKSGGESGMVEVYVALILRGKKTIEEVPAVIR
                     EQVRIRCKELEIPVE"
     gene            complement(37751..43072)
                     /locus_tag="KR231_000129"
     CDS             complement(37751..43072)
                     /locus_tag="KR231_000129"
                     /inference="COORDINATES: protein
                     motif:HMM:NF012632.1,HMM:NF024930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0002549.1"
                     /translation="MKRTKLLQRGNFFGDKNMVVDEFDEGYDNYDFINFFTGCCNYTF
                     GLKNNNILYGCGDNSNFQLGLGEDNTTRKLFTKIPNISTNIKKVACGESHAVILTSDG
                     ELLVAGINTDGQMGLGLEKVGKTVSTFEKVPEIKGVKDIACGLQSTYLLYNDGTLYVA
                     GNNLYGQLGLGTNGASANVNTFTKVDVDNVKAVFSYNKSAFIIKNDNKCYSTGFNNQG
                     QLGLGDKNNRDLFSLVSINDVKTIACGSEHTVLMTYNNDIYGCGKEKCFGNALQSSLF
                     TKIEEVNIKTIACGHGNTMLIDNKGTLKVAGNNDIYQLGIANYSENIDNSFIDLKNIV
                     AKNIFIGLSHSILIDSNNDSYCTGDNTYGQLGSFFDDMHIVEFKKMDSEKYSYSNYIN
                     LIKSEDKLTLLKEEMEIKDIELPLDIHSVRDVVFSPYCTLVILGNGDVYGLGNNRYKG
                     MGSDLPSQLNELTKLSISNVKSIVASKNISGGIFYIKNDDTCYYSGPNSNSIAGVLPS
                     NSDVFKKISIDNVKKVVINTDLSNWFSLIVTNNKQIYTSGKSSSYVNGLSNALISQYT
                     EISLSNVTDAYSSYNATFIVVDEKKVYATGINTNYLLGFSTSDGSNVNLGLLSDWYYI
                     NISGSSYSRVSCTNNITKINNIIIYEYVTVFCTNIGSFLTGYHGTSWTKPTDSSYRVQ
                     YQGISYAGYLDSYIYNYYPTRCTQSSSSTTFAYLYNGESSSNLKNVNPDNLLISGGSS
                     YIHQYGRNYLNNQSSNNIAASNINSGPITSDKAIFLYKALLYLSSNTLYGFGNISESA
                     KELDVSDTQDGYNATNYKKVMKNIKNIFIPPYDLSRDKTRFAILTDKSLFICGYNSKG
                     THGISVNSSLNLNNKINYNKKNSSSEISSNIQEIYSHSKSTYLLTNNNMLYSVGLNDV
                     GQLGVGDEINRKVFTKINIDNIKSINVNRFTDNSKHAFAIKNDNTCYAVGLNNSGQLG
                     IGDNVNRNIFTKINVENVKYVAVYGNTSLLLTNDGLLYGAGNNGKGQLGLGDTTSRNI
                     FTRIPINGVRDVYLCNDVSIIVKNDNTCYVCGLVNGYFGFTEGSISTFTKINIENVKS
                     VVTAGSEATFFITNDNMIYTTGKKERVFFSTETNDIKGIRVINNIINAKKIVVNGYTS
                     AILTNDNKLFVGGLSGYGSIANNNNTNSVEDVKDVFVTANNTLYIDNNNNLISSGRDT
                     YGISDESYRDMSVPYYKVSIKKDVDTVFSSYNTIFIKDIYGKFYSSTGDNRYNHLGIH
                     HRYDNDKNEALEGSLHSYFKTDNTSDKIVFNKKNEKLVMFNDKYIKTNNKYINYKNIF
                     KDNFKYTSIILPFEVSDIDISKTHSLAVAKDGKLYGIGSNSYKEINQTLEDIELLTLT
                     EVNISDVKKVACGDNYSYIIKTDNTLWSYGKNTEYQLGVGHNNDVRELQKVTGLPSVK
                     DISIYNSMTLVLTNEGELYAQGYNTNGLFGLGESEKDKIIRTFTKVLTNVKEIKSHND
                     DHILVIKNDNSLWITGKNKSMYKISISITDLYEFTKIPIPEHLNDILDIELSDDTIYM
                     ITKVDTSKASIEIVEKSISQVRVVVQDPNNVIEKLEMFINDELISTKTNLEINSIIFE
                     IPQNKIVLGENKILIKASSPTGDLYSSMFIFKSETGLKVKKDSILMINNKVYSIINIT
                     ENNTDLIVTLNEGLKDDMMENNPIYQLINKTKVQVKINKSDLFKDMKLVEIKKSDSSY
                     QEIYELEEANIKSAQPKIIVEKGDKWTAIKRPSMIFRYDAENNEPQA"
     gene            complement(43089..44072)
                     /locus_tag="KR231_000130"
     CDS             complement(43089..44072)
                     /locus_tag="KR231_000130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HBH0002550.1"
                     /translation="MEEKFYIILTKIGREKIANATALGELVGLTKFQVGDSNGEYYEP
                     TEEQTALKNVVWEGNINSLRIDEKNPNWIVIETILPGTVGGFMIREAAVLDNENNIIA
                     IGKYPETYKPRAEDGSIKDLVVKMILQLSNTSNVTLEVDPTLVFVTQKDIQDLDDKFD
                     KNIKEIKVKIGEELLSTEAKNLSGAINEVVEKIKNISIDDVIGGQIQTELSVLKNSYN
                     KLSEKVLDILIYLELESEIDVDEAGYWYDTLTNAKNIIAIEGLKLDLNRKCITGELGS
                     VTFKNVVLPFNANRVRYIHEMDNNFVETKSNRAYSIGQTDITLNKYSYEIR"
     gene            complement(44073..44771)
                     /locus_tag="KR231_000131"
     CDS             complement(44073..44771)
                     /locus_tag="KR231_000131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2313 domain-containing protein"
                     /protein_id="HBH0002551.1"
                     /translation="MKLIDKLPSFDRNYIVEEIQGAYDTELNILKEDIDDTFNQLFVD
                     TATWGLDMWEDILCIEKKELDFDTRRSNIKAKMRSRGTSTIEVIKSICEAYTKSETDI
                     KVYSDEFTFVLSFIANNCDYKTLLDCSDMIERVKPAHLLHYLEPIILDKSMVYCGGGM
                     VCSEEVKVHPYFEPIIKCSAVVNCGAGMISREEIKVYPLSIKCIENNCKINIAIANDT
                     GVENVVVYPKSEVV"
     gene            complement(44768..45820)
                     /locus_tag="KR231_000132"
     CDS             complement(44768..45820)
                     /locus_tag="KR231_000132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="baseplate J/gp47 family protein"
                     /protein_id="HBH0002552.1"
                     /translation="MYSDQTYEVIKNRTLENINLDIYKGEGSFLNNMVSGNNLELSKI
                     YLELSKMHKMAFIQDTYNQFLDKRVNEFGVYRKLGTESNGEVEFIGEKGTVINNGTII
                     SYRDLLFVVIKDVTIGSEEGDNSPVQALEVGKKYNLPTNCEFKLVDNISGVTKITNTR
                     SFEGGTDIETDEELKERFYKIQRNQATSGNKAHYEEWALEVDGVYNVKVYPRWDGPGT
                     VKVLIFGKNNQAVDTETIERCQQHIDEEKPIGPTITVVTPLPIEISISAVMKLEDGYT
                     LDNVKESFLESINTYFRDIRGEIIYTKVMGILINTTGVHDLSNLLINGSTDNITINED
                     KIPSVTTVNFSEVENQ"
     gene            complement(45813..46241)
                     /locus_tag="KR231_000133"
     CDS             complement(45813..46241)
                     /locus_tag="KR231_000133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2634 domain-containing protein"
                     /protein_id="HBH0002553.1"
                     /translation="MSTIFPFIGVPEDYILPKTEELPIFREVAWDFEKDEPILEKGDF
                     KIIEKKEALKVWIYKCIKTNRYEHEIYSLEYGTELSELIGQKYTKGLTESEASRFIKE
                     ALLINPYILEVNVKSANFNRDILSANVKVSTIYGEVEINV"
     gene            complement(46241..46567)
                     /locus_tag="KR231_000134"
     CDS             complement(46241..46567)
                     /locus_tag="KR231_000134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2577 family protein"
                     /protein_id="HBH0002554.1"
                     /translation="MANPINEFIGIIREEGKYHNQPSFFIGKIKSKLPDLKIETNNII
                     LEKEDILIDSWMIDRQLETFDTETNQEHQHEVKNPFIDNFESGDMVIMFRIGEKFAVV
                     SKLVSL"
     gene            complement(46583..48112)
                     /locus_tag="KR231_000135"
     CDS             complement(46583..48112)
                     /locus_tag="KR231_000135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C40 family peptidase"
                     /protein_id="HBH0002555.1"
                     /translation="MIINRSKDSSSNEISFVSKDMGFLLTQSEVSYNFKDKLVEDIAK
                     QVFAENRLSVGIIAKTNVKYTKMFIGVNGYDTIMSAYTEASKKTKKKYMIEANLDKFN
                     VIEKGTVTLSVMFEEGFNIINTTFSESMENVKNKVIVVDQYGSKISEKIDNEIFKEVN
                     VIMQKVIQQQENQDVDIDSEFNGIEKSCSLKGYGDVSCITGRGVKVKDSYTKLVGLFY
                     IDTDKHTWQNGEYQIELELNFQNLMDEKSAGQDEPKEESNLGGEDYAGGKEFTAEFTA
                     YCPRKEEGGDTDCRKKKLDPSKKTCAAPMVGKYEQTYYTKEFLNKHPLLNYGDEIQVI
                     TGVSGRDGVYKVNDVGPAITIEKNGTYHIDILFGNVEEASKFGRRKGKIIIGGYSGNV
                     SDKAKIVISEAKKHLGKPYKWGGNGPSSFDCSGLMVYCFKKVNVSLPRTSNQQSKKGK
                     KVEQKNLQAGDLVFFHNPVSHVGLYIGNGEFLHAPQKGDVVKISKLSSRRDFNTARRV
                     L"
     gene            complement(48394..48816)
                     /locus_tag="KR231_000136"
     CDS             complement(48394..48816)
                     /locus_tag="KR231_000136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0002556.1"
                     /translation="MEMWLRQAEDRFRFPVFPSSFSINGKAAVNSSSILKIGEIATFG
                     GVALKSISISSFFPNKDYTFCDYTGFPSPYDCVNKIEKWMKEGFILRFTITETNINME
                     VIIEGFSYEERDGTRDVYFTLDLKEYKRIKIPKVTPKQ"
     gene            complement(48816..51269)
                     /locus_tag="KR231_000137"
     CDS             complement(48816..51269)
                     /locus_tag="KR231_000137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0002557.1"
                     /translation="MGNVREEGINMYLTDNYTPKMNQIISVTDNFRRATVAVSLSTNV
                     MASSIKNSIGSASNRVNSLNSSLRKVQTTASSVSSTMTKLSSSINAVSGVIGSLNGSI
                     MRLAITIAMIIDYFNKLIQKKNEFNSNIMIILIFKAKSDEVEKTKNKLLGNLKKIGGK
                     IWNIVIKAKDMTKRVISSILGKLKQVEKRPYQGSINLKDMVSSAMGRILPKLMLFKNT
                     FWSGVIAIKDMASGIISKVFPKLRLFAGKVWSGAIAVKDMASGILGSIKGKISDLTNG
                     ATIGVAVKKGVDLLGQEQNQKVVLESVMKRNTGKVNQIDVDDYYGSLVRMANDTPFDP
                     EDVVAMGTKAKMISNITGGKKEKDITQAMVDVRALNMNTSSEQDVSAAFLSAAKGNME
                     SLNTLVGENYKTFDEALEGISVKQMGLAKEMSNTIPGIISGAQTSINNGLKSIVKPFD
                     DILGQGLKKIKTFIESGLGNLAGLSEKMAGKIGNVMNGKIIIGNKYDQMQSRSVKNGK
                     EFSDSTQYRISNEAEKRKMMVENKQERFENHAATMIGNAPKAIVNAGSTLLQNIDFTA
                     LIDSLLPVVNLVNNLLDSINNKSPIAQGLISIFGTIVTTAFQLIGPVVEAVSPIITRI
                     FTFLGEYAPQINNFIETLGVIWKTVWETLGPLLETGWKIIEPILGAFFNILDKVCKIV
                     KDICKWWQTMINKIKNGSITGTVLNLVEKSKKNYKDNPYAGTKAGDSGKAYSGKKGNN
                     AFGLNYVPYNDYQTRLHEGEMVLTKQEANQYRSRKNGGNINIAKLADTIVIREEADIE
                     KITSKLVASIQLAQLGGVL"
     gene            complement(51269..51436)
                     /locus_tag="KR231_000138"
     CDS             complement(51269..51436)
                     /locus_tag="KR231_000138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428173.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0002558.1"
                     /translation="MYYYWKKKGIRPSLFYAMDKGELKLIEAFFALEIEEEVEKMKHG
                     YGVCPLTGGGM"
     gene            complement(51463..51909)
                     /locus_tag="KR231_000139"
     CDS             complement(51463..51909)
                     /locus_tag="KR231_000139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428176.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HBH0002559.1"
                     /translation="MSENGLSKNINIVDLLLNSDTENLERPSTIVELKRLSTIFGQEF
                     KVMCRALTISKDEEIQNTCLKIDENMKTDIDLPEMQMLTIIEGVCDLDGKLLFKNKEL
                     MDKFKAPTPKELARKLLLPGEITNLYRILQDVMGYGKNAVIEEVKN"
     gene            complement(52023..52451)
                     /locus_tag="KR231_000140"
     CDS             complement(52023..52451)
                     /locus_tag="KR231_000140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail tube protein"
                     /protein_id="HBH0002560.1"
                     /translation="MANMEARNVMSGTWGELWLDGNKVAEVKKFQAKMEFTKEDIIIA
                     GQMGTDTKYMGYKGKGSITLYHVSSRMHKLIGEKIKRGSEPRFVAISKLNDPDSYGAE
                     RIAVKNIAFDDLTLADWEVGVKGEIEAPFTFTEYDFLDII"
     gene            complement(52465..53529)
                     /locus_tag="KR231_000141"
     CDS             complement(52465..53529)
                     /locus_tag="KR231_000141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail sheath subtilisin-like
                     domain-containing protein"
                     /protein_id="HBH0002561.1"
                     /translation="MAIGLPSINISFKELATTVKERSARGIIAMVLKDAKALGLNEIH
                     EKEDIPVDLSAENKEYINLALMGNVNTPNKLLVYVIEGEADIQTALDFLETKEFNYLC
                     MPKAVEADKTAIKNWIIKLRDIDKVKVKAVLGKVVGNHEGIINFTTEDVLVGEKKYSV
                     DEFTSRVAGLIAGTPLSQSVTYTKLSDVVDIPKMTKVDAESRVNKGELILIKEAGAIR
                     IARGVNSLTELTAEKGEMFQKIKIVDTLDIIHSDIRKVIIDDYIGKVTNSYDNKCLLI
                     VAIKSYLEELEKSALIESDSTVEIDFEAQKSYLKSKGVDLSYMTLQEIKEANTGSKVF
                     LKAKIKVLDAMEDIDLSIEI"
     gene            complement(53534..53977)
                     /locus_tag="KR231_000142"
     CDS             complement(53534..53977)
                     /locus_tag="KR231_000142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0002562.1"
                     /translation="MLKYKEILETIIEILKKNFTESIFIDDESVQGSEGSCFFVSILS
                     VICTPVMLNTNNKDIVISIKYLPKPQSKSIRMYEISDELNKLFNRNIKVTDRKLNITK
                     LEQSIKKEESIYVLNFTFTLNYLDSVYEEDVVYENMKEINLNLGE"
     gene            complement(54226..54666)
                     /locus_tag="KR231_000143"
     CDS             complement(54226..54666)
                     /locus_tag="KR231_000143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0002563.1"
                     /translation="MENKKDILFKETDKRLHNYKYLDIKIKNINLDIKRCENEYSGCG
                     AMVYTEKTSNTYNISSSVENEVLKREERLRKLKMEKEDIEIEKEKIENALTCLNDIEM
                     EFFNLFYNSKTKNNMTYISMKLHLDRTSCYNLKKKMIFKLSEIL"
     gene            complement(54771..54968)
                     /locus_tag="KR231_000144"
     CDS             complement(54771..54968)
                     /locus_tag="KR231_000144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBH0002564.1"
                     /translation="MFKNNLKYYRKCKGMTQIQLARKAGITNDYISQIERGIKNPGLL
                     MAKKISSILEQNIEEVFFIQL"
     gene            55137..55457
                     /locus_tag="KR231_000145"
     CDS             55137..55457
                     /locus_tag="KR231_000145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
                     /protein_id="HBH0002565.1"
                     /translation="MFAKRLRELRKEFGLTQRELGEKVGVSQRVLGYYETENRFPDEH
                     ILNKLADVFNVSVDYLLGRTLVKENIDTVAAHRKNPHEELPEEAQEQLNDYIEFLLNK
                     YKKK"
     gene            55539..56045
                     /locus_tag="KR231_000146"
     CDS             55539..56045
                     /locus_tag="KR231_000146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0002566.1"
                     /translation="MNNLDKLFELASQEEIIIHYTTYIAGDLEGLYINKHGIKIISLL
                     SNLKQNSKKLTSILAEELGHHFTSLGYYVSSYNDYYTKIIIDKCENKALKWACEFLIT
                     EEDIINIINSGITCVYEMADILNVDITFFQKRLEFLSLKKQSLQLGNNKYLILTNLPY
                     FYIFDPIS"
     gene            56746..57501
                     /locus_tag="KR231_000147"
     CDS             56746..57501
                     /locus_tag="KR231_000147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889131.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HBH0002567.1"
                     /translation="MEKKVLATVGEKEITNIDIENALKSLDPYQAMQFKTEEGKKHLL
                     NDLVNQELFFLDAKEEKLDEEEIFKLEMKKIEENVLKQFAINKVLSSVNVTEDEKVKF
                     FEANKSSFSKPESATAKHILVDSDEKAKEILAQIKSEEISFEDAALKHSSCPSKDMGG
                     DLGTFGRGQMVPEFEEAVFSMAKGEVSEPVKTQFGYHIIKLEDLQESTESTFDEVKAE
                     VEKSLLYQKQNEVYGNKINALNAKYGNLVKYND"
     gene            complement(57644..58072)
                     /locus_tag="KR231_000148"
     CDS             complement(57644..58072)
                     /locus_tag="KR231_000148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889129.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HBH0002568.1"
                     /translation="MNILFFLTPKSEVAYIYEDYTIRQALEKMEYHKYSAIPIISKDG
                     KYVGTITEGDFLWTLKNDLNLDLKGLEDVPVTDINRKMDNSPVSINADIEDLVIKSLN
                     QNFIPVIDDQDTFIGIIKRRDVIGYCYEIIRGYKNLANDN"
     gene            complement(58493..58693)
                     /locus_tag="KR231_000149"
     CDS             complement(58493..58693)
                     /locus_tag="KR231_000149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HBH0002569.1"
                     /translation="MKTGVVKWFNNEKGFGFISVEGEGDVFVHFSAITGDGYKTLEEG
                     QSVEFEVVDGAKGPQAANVVRL"
     gene            complement(58876..60045)
                     /locus_tag="KR231_000150"
     CDS             complement(58876..60045)
                     /locus_tag="KR231_000150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidase domain-containing protein"
                     /protein_id="HBH0002570.1"
                     /translation="MGGVALKILKNKNKYIKGIMAFVFLSLATTAGVFLINDLSMKNM
                     EEKVMESANVEGDDVKDQYKLLLENLFDYRNKAILEKNENILKGLYETDKKFGLWAYE
                     NEVKKMKYLENWSSKQGVKFKDIKTRVKIKKIKEKEKDLYGIICSVSTEYKYSYENQK
                     DKENAFRIGTYHYLNVKIIDNQYVITKEWYTDPFADSLNLENIKSDDIRNYIGQQDGV
                     ELQLTDEQKKAIDYAHKYCGAAADEEHGMKFNPNYRDYNPEGGDCANFASQIMFESGR
                     FKKNSIWNYSERAGTKAWVNAQAFKNYALYSGRGSLIAKGSYEEVYKEAYNLRPGDFV
                     GYEKKGRITHVSTVTGLDSRGYPLVTCHNTDRMLVPWDLGWSDKSIRFHIIKINY"
     gene            60281..61102
                     /locus_tag="KR231_000151"
     CDS             60281..61102
                     /locus_tag="KR231_000151"
                     /EC_number="2.7.1.35"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxamine kinase"
                     /protein_id="HBH0002571.1"
                     /translation="MQKKVAAINDLSGIGKCSLSVAIPILSALKVQCCPFPTAILSSQ
                     TGYPEFTFLDFTDEMVKYSNVWKNLKVNFDSIYSGFLGSKHQIEIVANFINDYPNAFI
                     VVDPVMGDNGVMYPIFTEEMRHEIKELVKHSDLTTPNLTEACFLTGNDYTKSDYNRDE
                     LIYIAKSVSDLGPSKVVITGILEDDNILNLAYDRDNDHVFFTSVKYNNCSYSGTGDIF
                     TSILCGMLVNKHDLGVAVNTATDFIYKTINYTSQFDTDRNDGVMFENFLSDLTNI"
     gene            complement(61178..62566)
                     /locus_tag="KR231_000152"
     CDS             complement(61178..62566)
                     /locus_tag="KR231_000152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system sensor histidine kinase"
                     /protein_id="HBH0002572.1"
                     /translation="MLGGKKSNNKKVEKLRTIFIKYLSLFFIMTISIVLLLMLSFSVL
                     LSSGVILPANYAEKQFNKYKEQIISSEKVTEDIIPSIYEYGVYTLDGSLISGTFNKKE
                     SKEVWNLMRDIEERHAYSESYIKFFKKDEVFIIKYKIVSEYSSPILRAYLPKPETLGM
                     IIFSIIFFIEIVILSKVFGKKFNIEMELLKNTTEKIEQQDLDFVVESSKIYEINNVLF
                     SMDKMKLALKDSLEKQWMLEENRKEQISALAHDIKTPLTIIHGNTDLLIEINENPELL
                     EYMEYISKGVTQIEKYINTLIDISKTENGYILNKEAISMSEFIKDVLVQIEALASTKN
                     LDVEFYKQDNLPKNITIDRELLFRAIMNIISNAIDYSPSQSKLYISVSVRNKYLKFVV
                     TDCGSGFSKADLSKATEQFYTGDLSRNSKSHYGMGLYIVNNIVQKHNGILYIENSVKT
                     GGAMVTIEIPIV"
     gene            complement(62701..63459)
                     /locus_tag="KR231_000153"
     CDS             complement(62701..63459)
                     /locus_tag="KR231_000153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lantibiotic immunity ABC transporter MutG family
                     permease subunit"
                     /protein_id="HBH0002573.1"
                     /translation="MRQLIRIFCSDLIKLKRNFIILMHICIALMGMGLFLWYYKVSGA
                     DNILKIVAYLQVIAIAFPLLSGVVCSMFVEQEYYAGNYKHMLTTSNPKYLTLISKYII
                     LVCLGFVATLVSVLGFKFGISKAYFASSFYMISILILIGCNLFEYILHLFLSLRFGKG
                     TSIGVGIVEMLLSALLLTGLGSGIWQYFPCAWGVRFITIWSSFSSSKTVEYIKVESIK
                     AYQSTGLMCGFVTILAFVILCIWFSKWEGKKSEE"
     gene            complement(63461..64177)
                     /locus_tag="KR231_000154"
     CDS             complement(63461..64177)
                     /locus_tag="KR231_000154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lantibiotic immunity ABC transporter MutE/EpiE
                     family permease subunit"
                     /protein_id="HBH0002574.1"
                     /translation="MERFIRVEFQKMKGTFGMKLIWIVPVFCILLCGLGGGQNAAFNW
                     WYTTFLPGALTLISSLIVLKDEKSKYRGILPLPIEMKDVWTGKMIYCIICCFIASIIS
                     AIGVVFVGIIYKETISIGQNIIATILIILLFMWQIPLCMFLASKFGIFVTVLINMFFT
                     IVGVAVFSTTEMWYMFPYSIPSRLMAVVLHILPNGLPVPEGSEFLNNAVILPGVLISI
                     VLFVLFALATRVWFNNREVK"
     gene            complement(64179..64886)
                     /locus_tag="KR231_000155"
     CDS             complement(64179..64886)
                     /locus_tag="KR231_000155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lantibiotic protection ABC transporter
                     ATP-binding protein"
                     /protein_id="HBH0002575.1"
                     /translation="MSNYILQVKGVSKKFKEQMAVDNISLAIKSNSIYGLLGPNGAGK
                     STLLKMITGILNPTSGKIMFEGHRWTRKDLSNIGSLIESPAIYENLTARENLKVHTTL
                     LGLPDSRIEEVLETVDLRDTFKKRSGQFSLGMKQRLGIAIALLNHPKLLILDEPTNGL
                     DPIGIEELRELIRSFPKQGITVILSSHILSEVEQVVDEIGIISNGVMGYQGEVSKEQN
                     LEKLFMKVVAENRKRGQ"
     gene            complement(65002..65538)
                     /locus_tag="KR231_000156"
     CDS             complement(65002..65538)
                     /locus_tag="KR231_000156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein"
                     /protein_id="HBH0002576.1"
                     /translation="MNKIAVSFLIIATTLLSTACMDYSISAVELVDSKESAVVKKDED
                     AKEETTSKMINSKKTTKIPIEIISKDEKIVKYLQIDEESSLKDKLRLILDTLSNEYFN
                     GLDMEVEVKEKDNLVKINLIEPDKKSRVSWKDDYLNEQNIIYTINNIIKNVIQEEDNS
                     IWIEEVEIYYNGKLIELR"
     gene            complement(65640..66710)
                     /locus_tag="KR231_000157"
     CDS             complement(65640..66710)
                     /locus_tag="KR231_000157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4097 family beta strand repeat protein"
                     /protein_id="HBH0002577.1"
                     /translation="MNKKLAIFAAVLLVIGIIGTTWSGILVMPSLINFGLEKEAEFKK
                     ENKLYQEKVNIDKLDIAVDNINVTIKKSSSEDVRVTTRGNNEFYKYNVTLKDKTLVVK
                     GERKYENKIKKIKNFDQLLNTSINSMFSHDYREIIIYVPNNVDINASSISSHLFVYDN
                     VASNTITYKTSYGGFSRAITENKVNRLENLNLISNNNLHLSTKSILGVKNVNIESESL
                     YISSENEDVFINNIEEYIPENVNIKEKIGRNSNYESEFYLYSDMPIAKFLDIEVPNSK
                     VRLDIPVNKYKFNCDIKSKEAIEEFNNDEEYDNDSYDYEHSEEHSNKYRNTREIKGLL
                     NKNLSNLEKEYTIKINSNSLEL"
     gene            complement(66703..67761)
                     /locus_tag="KR231_000158"
     CDS             complement(66703..67761)
                     /locus_tag="KR231_000158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1700 domain-containing protein"
                     /protein_id="HBH0002578.1"
                     /translation="MNLNKTEFLEILKDYLKKDFSESEVNDILRDYEEYFVDGLIEGK
                     SDMEIIASLGSPKSIAKELILQTKEKNIEEEKIINTDVLNDKFSKFKSDMKKGYSILK
                     DEAKEKYSKSKENIDGKIMNTDILNGKFSRFKSNVKKDYSILKDEAKEKYNKSKENIN
                     DKLTPSIEEGVGGLSRQVIKGLLVVLSLFLIVPAFAFVCAIVSATIALVCSLIAFVIL
                     IPFVIKFIAMVPDVMMFCIFATIAFVGLEILAWQILLFAIKLGKQLLNNYIHWIKRKN
                     IYIKANEKMEKRKKATLNDEDLNKDINEDSYNNDYYNREEESIKETDEYNDDSINFEA
                     IYKDLEDIENKKGEDKHE"
     gene            complement(67748..68080)
                     /locus_tag="KR231_000159"
     CDS             complement(67748..68080)
                     /locus_tag="KR231_000159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HBH0002579.1"
                     /translation="MNTQFRKGVLEICVLALISKKDMYGYEIVHNISKVIDVNEGTIY
                     PILRRLTKDLYFETYILESNEGPARKYYRITSLGKENLSNLMEEWREFVKAVEILISE
                     DEGGNELE"
     gene            68279..69400
                     /locus_tag="KR231_000160"
     CDS             68279..69400
                     /locus_tag="KR231_000160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactosyldiacylglycerol synthase"
                     /protein_id="HBH0002580.1"
                     /translation="MKDDKTILILTAQFGAGHISAAKAVKECIIEKYSNYNVVIQNFI
                     NASIPMMNKPMVKLYENNTKYTPGLYNYYYYFKKSFDSRHDLSHKLYTPKLSEYIADI
                     NPDLIISTFPLAAACVNNFKIKNPDINIPTLTVITDVVDSMEWVFENTDLYFVPSPEI
                     KNRFFQKGINPDSIKVTGVPVDKRFQIESKELCCDKYRLLLLGGGRGLFDIDEDFMHW
                     IDEFIEEHSNSIEITIVTGKNKKLYDNLTHKKPLKNIKVLGFVNDMYNLIRECDLMLT
                     KPGGATIFEAIQSQTPVLVKMPKVGQEIENAKFIIDKGLGMIYSDDLDLKNIFYKLVS
                     NEFDSIINFMKKNLKEFKTVIHPEKIADYISELIDNHYS"
     gene            complement(69528..71426)
                     /locus_tag="KR231_000161"
     CDS             complement(69528..71426)
                     /locus_tag="KR231_000161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine synthetase"
                     /protein_id="HBH0002581.1"
                     /translation="MDSLLYVIEKDKHTNEELREILKSNKNIRFVSLMGVDLGGNATD
                     EKIPVELFLEDIDKFLESAIQTDGSSVELYNIATLNNAKVDLMPDKSCHWYVDYNMEY
                     IDEEVGLPVGTLKIPAFLIHDNKKVCSRGVLQKADKYFKKSMYEIFREYPHVINNIGI
                     DSVDDIEEIMLTAATELEFWVNTPEDKADLEKLYVSQSLKEQYWKRTHGIIRTCLEKS
                     LIILQKLGVNPEMAHKEVGGIQSSISIDGRTNHAMEQLEVSWKFSTPLQAADNELLVR
                     DVIEDVFTSHGLEVTFKAKPIHGVAGSGGHTHVGVSAKLKDGSIKNLFAPKDLKEDYL
                     SELGYGALMGLLYNYEVLNPIVTASNDGFNRLVPGFEAPVCIVTSLGHSYEIPSRNRS
                     VLVGLIRDMKNPKTVRFELRSPSPLSNTYLVIAGCYQTMLDGIKAAAKSGLSTKELEK
                     ELSKNVGEESFYLEKDRAYRDENDVFEHYSLEERNARFGIPPATVYENMKNLEIYASK
                     LKSLKQGDVFTDSIIESFKIGAIDKWQKKLKTRIIEAGIQKIRSIVKIHTKENMDALD
                     EVVWNSISDLKFNIMKDTLTRESLFTRVREAIENKDYQTASDLQIELKRSMEEIQQLY
                     MQYKKNIY"
     gene            71741..72517
                     /locus_tag="KR231_000162"
     CDS             71741..72517
                     /locus_tag="KR231_000162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exonuclease domain-containing protein"
                     /protein_id="HBH0002582.1"
                     /translation="MEYIIFDLEFNQGFDKKLNKTVSNEKCPFEIIQIGAIKLDSKFN
                     IIDTFNSYVKPTIYKDIHPFISRMTNIKNSDFNDSPTFPEVYNNFIKFISSQDPILCV
                     WGAGDLKELYRNINYHKLPSNSLPKSYINIQQHASKYFNNPAGKSIGLQNAISILELD
                     EKMSYHNALNDAYYTAKVFIKIYNPSIVPDIYLYTSIKPKTIRYSNKKRVDYDKLFDE
                     FRKILNRELTKDEKKIINLAYNMGKTNQFTLENVKQRKNK"
     gene            complement(72609..73361)
                     /gene="xth"
                     /locus_tag="KR231_000163"
     CDS             complement(72609..73361)
                     /gene="xth"
                     /locus_tag="KR231_000163"
                     /EC_number="3.1.11.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease III"
                     /protein_id="HBH0002583.1"
                     /translation="MKFISWNVNGIRACVGKGFLDFFKEVDADIFCLQETKLQEGQIE
                     LDLPGYFQYWNYAERKGYSGTAIFTKKEPLKVMYGINIEEHDKEGRVITLEFEDFYFV
                     TVYTPNSQSELKRLEYRTRWEDDFIDYLTKLDNHKPVIVCGDMNVAHKEIDLKNPKNN
                     MKNAGFTKEEREKFSKLLDSGFIDTYRYFNPDKEGVYSWWSYRFNARKNNAGWRIDYF
                     CASKKLEDRLVSADIHTEILGSDHCPVELEIK"
     gene            complement(73522..74472)
                     /gene="galT"
                     /locus_tag="KR231_000164"
     CDS             complement(73522..74472)
                     /gene="galT"
                     /locus_tag="KR231_000164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-1-phosphate uridylyltransferase"
                     /protein_id="HBH0002584.1"
                     /translation="MKELRIDPITNDVVIFATDRLKRPLDTADIPNEDEETNEYDEEC
                     PFCKGNEAHATDALFEIESEEGWLVKSVYNKFPIIDDMARDVYGVHEVMIESDKHNRS
                     FYNMSQKEFEDVFFMYRNRFRDLSKDDKVEYVSIFKNFLRKAGASLMHPHAQILSMSF
                     IPPEITNELLVSKEYYDSNKSSLYDDLIENEISLDRRVVYNGEAFLVLIPYATKYSGE
                     VRIIFKDKIEFGELNDNNIQELSTIFEKLFKKLYNINGYMPFNLCIHTHPTKIETKSY
                     FNVHMHIIPRKYNFGGFELGTNMYVSSMSPEDLTKKLKID"
     gene            74857..76053
                     /locus_tag="KR231_000165"
     CDS             74857..76053
                     /locus_tag="KR231_000165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HBH0002585.1"
                     /translation="MNYSNRVSAMQASPIRKLVPFAQAAKDKGIKVYHLNIGQPDIKT
                     PKGFFDAVKNFDSEVLEYATSEGIPELLEALQNYYKTYDMNFEKDELLVTNGGSEALL
                     FTMMAVCDPGDNLLVPEPFYTNYNGFGQSVNVEVNAVTTKAENGFHLPSKEEILSKVD
                     DKTKAIILSNPGNPTGAIYTKEELNILAEIAKEKDLWIIADEVYREFVYDGLEYTSCG
                     NLEGVQDRVIIIDSVSKRYSACGARIGSIACKNKGLIAQILKLCQGRLCVPTLEQIGA
                     VELYKTPVSYFKEVNEEYKKRRDVLYNELMKVEGVICKKPTGAFYIVAKLPVENAEDF
                     TIWMLKEFNKDNETVMVCPAEGFYATPGLGRDEIRLAYILNEKDLHRAATLLKEGLEQ
                     YVALQK"
     gene            complement(76165..77505)
                     /locus_tag="KR231_000166"
     CDS             complement(76165..77505)
                     /locus_tag="KR231_000166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428207.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-alpha-glucosidase"
                     /protein_id="HBH0002586.1"
                     /translation="MKKRYNIAIVGGGSTWTPGLLKSLCKMSDRFPLNKVTMLDVVEE
                     RQRLIGEFGKILFKEEYPKATLEYTTNPDEAFIDVDFVFVQMRTGGLKMRELDEKIPL
                     QFGLVGQETCGAGGFAYGLRSIGDMIEMVKTVRKYSPKAWILNYTNPAAIVAEALKRV
                     FPDDKRLLNMCDQPVNLLRSYGRLLDMDSRTFEPVYFGLNHFGWFTHLYDKNGEDLVP
                     KIKDLVANSGFQPVDAEQRDKSWLDTYGMVKDMLEDVPDYLPNTYVQYYLYPDKKVAK
                     SNINCTRAREVMNGREKRVFEECKSVIEKGTSIGSNLVHNDAHGEFIVEVAEAIAHNK
                     HQIAIVITENNGAISNLPDDAMVEVAAILTKNGPRPLHVGNIPTFYKGLLEGQLAYEK
                     LAVDAYFEQSYEKAILSLTLNRTIISPTKARQVLDALIKVNKDYWPTLYKENEK"
     gene            complement(77644..78396)
                     /locus_tag="KR231_000167"
     CDS             complement(77644..78396)
                     /locus_tag="KR231_000167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HBH0002587.1"
                     /translation="MNLIDKLDINQKKLSTNEISLLNYFLKNSEKINQKKIKDIANET
                     FNSTAYIVRFCQKLGFSGYSEFKNFLVFSYSNRNERNKEFTKSQSDIFTDVMDTQNLI
                     NVENIDMCLNEIHNSKHIYFFGVGSSRLVCTEMSQRFSAIGVNVKYYDDSTLMYLAAS
                     NITKDDLVIAVSMSGETAQVIKACNIAKTNQVKVISLTNISVNSLSNIADIKLFVSSP
                     QYNFNSVNYTSRVPALSLMEYMFHKYIEKYNR"
     gene            complement(78544..80121)
                     /locus_tag="KR231_000168"
     CDS             complement(78544..80121)
                     /locus_tag="KR231_000168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HBH0002588.1"
                     /translation="MKQKMKGFFLQLGKSFLLPIALISAAGIFLGISSAFSNPNIVSD
                     MPFLANNFIQGILGFTKAITGVLFGNLAIFFAISISVGLAKEEKAVSAFSGFVGYLVL
                     HTSVNYMLGCRGIIAEPDMMREMGQAVTLGIQTLELGVFGGIVVGIITASLHNKYYNI
                     KLPDYLGFFGGTRFVPIITTVVFSILGIIIPYIWPYVNTIIQSVGIGIASLGYLGTFV
                     FGFLERLLIPFGLHHILNAMFRFTEVGGSLVVGGQEVFGALNIFLAQLSDPETISFST
                     EATRFLAQGKIPIMVFGLPAAAYAMYKTAKPENRSKVKGILLAGALATFVTGITEPLE
                     FSFLFVSPILFVIHAFLSGISFMMMHIFGVAIGNTQGGIIDLVVFGVMQPNTKWIYSI
                     ILGLVYAIVYYNVFKILILRFNLQTPGREEITDINFDLKPLSNKVEIAQSGETTKRAL
                     SIIKYLGGKDNIEDITNCITRLRVVVKDMSKVDENAFKKYTGAMGVIKVSDKDIQIIY
                     GPSVSQVRDEVSFAMSI"
     gene            complement(80533..80985)
                     /locus_tag="KR231_000169"
     CDS             complement(80533..80985)
                     /locus_tag="KR231_000169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HBH0002589.1"
                     /translation="MNYIVKDTISFLVKTFPKIYSSLYLEDLKKFAPDYNVNKTQLRA
                     LVFIKNYGVISMTDLCSKLNIEKGSLTSMVDDLTDKKYVTRKRDLVDRRKYLIDITEE
                     GDKIATDFMDKLSDGLGEKLSKLTEEDRKKYLEAINTLQYILNKEEFR"
     gene            complement(81296..82741)
                     /locus_tag="KR231_000170"
     CDS             complement(81296..82741)
                     /locus_tag="KR231_000170"
                     /EC_number="4.3.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419557.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate lyase"
                     /protein_id="HBH0002590.1"
                     /translation="MIDNKYTTYSNPLTDRYCSKDMSYIFSPQFKFSTWRRLWVALAE
                     GEHELGINITEEQLDELRANIDNINFDEARKIEKEVRHDVMSHVKAYGLQCEKAKGII
                     HLGATSAYVGDNTDVIQMNEALKLLRVKLVNLINNLKEFALKYKDMPALGFTHFQAAQ
                     LTTVGKRACLWAQDLILDLEDLNYRIDNMKLRGVKGTTGTQASFLSLFEGDHEKVKEL
                     DKKICKKMGYHSSYAVSGQTYTRKLDYQVISILSGIAQSMHKMTNDIRLLQSLKELEE
                     PFEKNQIGSSAMAYKRNPMRSERIASLSKYIISESISPAMVQATQWLERTLDDSANKR
                     LAIPQAFMAADAILEIGINVTDGLVVYENMINRRVNEELPFMATETILMEAVKRGGDR
                     QELHEIIREYSMKAAYRVKHEGKDNNLIELIMNDDSFKMSKEEILSIMDPKNFIGRAP
                     EQVVEFVNEVVEPAIKDYKEDLGKVDVDLRV"
     gene            complement(82885..83793)
                     /locus_tag="KR231_000171"
     CDS             complement(82885..83793)
                     /locus_tag="KR231_000171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HBH0002591.1"
                     /translation="MYSTKILDDYEYETFNVFSTKLNPNTKHDYLSKVILFKEFLKGK
                     ELIYATKEDCKNFVDYIQTKYAKSTCEKIYSYLHSFYNFLKKEGYIDINPFRYVEKPT
                     VTRIKTKDDVLSIQEINKLIGILPKLNIRDRVIIVCLVTTGCLLNELVSLKWKDLMVD
                     ENDNSYVRLGKGRKERVVKLHPYFFKLLEDYRNYSGLPEVIIPSDDFIFTTQKSNSIT
                     DRNVRLIVKKALDLAGLSQYSARDFRHSFAAISLRLGADESDVKNQLGWSDKYYAIRY
                     KYVLNFVDSEIVDYLIEKDNLDINKK"
     gene            84050..84874
                     /locus_tag="KR231_000172"
     CDS             84050..84874
                     /locus_tag="KR231_000172"
                     /EC_number="3.6.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl-diphosphate phosphatase"
                     /protein_id="HBH0002592.1"
                     /translation="METFSLLEIFKAVILGIVQGITEWLPVSSTGHMILVDEFIKLNF
                     SNTFISTFLVVIQFGSILAVLVIFFRKLNPFDSAKNIKQKKETVRLWLKVIIAVIPSG
                     VIGILFEDDIDRLFFNSTVVAIALIVYGIIMIGLEKRNKKPKYKDFSQVTYKLALCIG
                     LFQCLALIPGTSRSGSTIIGAVLLGTSRYVAAEFSFFLAIPTMLGASALKLLKAGFGF
                     TGFEWLILGVGSVVAFVVSIVVIKFFMDYIKKHDFKVFGYYRIVLGIVVLAYFFLL"
     gene            84914..85444
                     /gene="lepB"
                     /locus_tag="KR231_000173"
     CDS             84914..85444
                     /gene="lepB"
                     /locus_tag="KR231_000173"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729595.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HBH0002593.1"
                     /translation="MSVKKEIFDWIKSIAMAIVLAFVILQFIRPSIVSGESMYPTLDD
                     KDYLILNRISYKVGKPEKGDIVVFKTNLVDGETGKKKDLIKRVIATEGDRIKISNSKV
                     YVNGKLLNEPYIHNNYTSGDIDTVVPKGKLFAMGDNRENSNDSRFPDVGMVDEDEVLG
                     KVMVRLLPLDNIGKVD"
     gene            complement(85526..87307)
                     /locus_tag="KR231_000174"
     CDS             complement(85526..87307)
                     /locus_tag="KR231_000174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UvrD-helicase domain-containing protein"
                     /protein_id="HBH0002594.1"
                     /translation="MSQYININSQLDALKLKEFEKIFYENINEDVKVVPKVTPFKGIN
                     TDLLYVKDGRILFIKFMDTTEDIFFILEEELLEVMNEEYELLKLKMGQKNRNISYNYV
                     YIMPYVEVEETYEFEEFVNNNIIDKNKLQDIMNKGSLEEYLNDENDEINLNLFLLDIC
                     SEYYIINDKLHLNEKFKKISFYNDDYKYTATMMEDVQIKDVVSIKYGNTLIEGGSGIG
                     KTAIMLSRAIKLAKVYPHHKLVIFTHTKQLCNELRERIELLYKDNNNLEVHTFSSFIF
                     KLAKKFNLIVDYNMLKNDYEKTFNNLVKQAQNIIKNKNMFKAIFIDEAESFLEYEIDF
                     IREFLYKTKFIFNVCSCNSLNISNRLNIFKKLYNGIEFDDKIILSKNYRQAKEIVDFT
                     NKFSNNSNSYINELRPNTEFSTFFYTKALRGGNKSVDIIKVSDLDDQISSVIWEIEYL
                     ISKKGLDYSEVAIVYPYNKKKLKSGKTIYFQYMLKKALEEAKIPYICAEDNLTNISKK
                     VGTTIANIYAIKNLEYKAVIVCELEMLYNQTINDIEQDYQVNDFVGDLNKVYLAMSRA
                     TDYLSIVTTFNEEASDIIRLITESKDI"
     gene            complement(87942..89483)
                     /gene="rny"
                     /locus_tag="KR231_000175"
     CDS             complement(87942..89483)
                     /gene="rny"
                     /locus_tag="KR231_000175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Y"
                     /protein_id="HBH0002595.1"
                     /translation="MDVIDSVVMIVIGAAVGIIAGYFVRKNISEAKIGQAENLAKEII
                     DKAHHDSETVQKEKLLEAKEEIHKWRTEAERENRERRTEVQKYEKRVVQKEEVLDRKL
                     QNLESKEVNLSEKLKVVEKKEEEVEVIKTQQLEKLESISGITSDKAKEIILTNAERDV
                     RREMSIMIKEIESQAKEEADKKSREIIGYAIQKCAADHVAETTVTVVSLPNDEMKGRI
                     IGREGRNIRTLETLTGIDLIIDDTPEAVILSGFDPIRREIARIALEKLIADGRIHPAR
                     IEEMVEKARKEVDNIIKEYGEQAAFETSVHGIHPELIRLLGRLNYRTSYGQNVLKHSI
                     EVAHIAGIMAAEIGADIRLAKRAGLLHDIGKAVDHEMEGTHVEIGMDLLRRYKESKEV
                     IHAMSTHHGDYEPQTVEAVLVTAADAISAARPGARRETLEAYIKRLEKLEEIANSYEG
                     VEKSFAIQAGREIRIMVKPEAINDEEIHLLARDMTKKIEDELEYPGQIKVSIIRETRA
                     IEYAK"
     gene            complement(89659..90705)
                     /gene="recA"
                     /locus_tag="KR231_000176"
     CDS             complement(89659..90705)
                     /gene="recA"
                     /locus_tag="KR231_000176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428218.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecA"
                     /protein_id="HBH0002596.1"
                     /translation="MSVDQEKLKALNEALGKIEKDFGKGSVMKLGEATSMSIDVISTG
                     AIGLDIAIGIGGLPRGRIVEVYGPESSGKTTVALSCVASAQKDGGIAAFIDAEHALDP
                     VYAKALGVDVDNLIISQPDTGEQALEIAEALIRSGAIDIIVIDSVAALVPKAEIDGDM
                     GDSHVGLQARLMSQALRKLTGSIKKSNCVAIFINQLREKVGIMFGNPETTTGGRALKF
                     YSSVRLDVRKIDTIKQGDKVIGSRTRVKVVKNKVAPPFKQAEFDIMYGEGISKIGDLL
                     DIAADVDIVKKSGSWYSYNDTKLGQGRENVKKFLEDNLDLTTEIDEKVRAFYNLNEEH
                     EESGISVSKEIVEE"
     gene            complement(90993..91535)
                     /gene="pgsA"
                     /locus_tag="KR231_000177"
     CDS             complement(90993..91535)
                     /gene="pgsA"
                     /locus_tag="KR231_000177"
                     /EC_number="2.7.8.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-diacylglycerol--glycerol-3-phosphate
                     3-phosphatidyltransferase"
                     /protein_id="HBH0002597.1"
                     /translation="MNLPNKLTLFRIFLIPVFVLIMLLNVPNKFLIACIIFIIASITD
                     ALDGKIARKYNLVTDFGKFMDPLADKLLVISALTCMIEDHLVSSWMVIIIVARELTVS
                     ILRAIAAADGKVIAAGNSGKLKTITQMVSIVFLLLGAQFENVLILNIGEILILIATLL
                     TLYSGWEYLYKNKELFMSSK"
     gene            complement(91522..92856)
                     /gene="rimO"
                     /locus_tag="KR231_000178"
     CDS             complement(91522..92856)
                     /gene="rimO"
                     /locus_tag="KR231_000178"
                     /EC_number="2.8.4.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S12 methylthiotransferase
                     RimO"
                     /protein_id="HBH0002598.1"
                     /translation="MLKIALESLGCSKNLVDAEIMMGILNNKGYKLIGDFEEADVIIV
                     NTCGFIESAKQESIDTIINFAELKKTGNLKLLIVTGCLAQRYSEELKTEIPEIDAIVG
                     TGSYQNIDKILKELSEMHQIVSLNDIEFVFNEDLPRYISTPSYMAYLKIGEGCSNNCT
                     YCIIPKLRGKYRSRKFEDIIKEAKKLAESGVKELVVIAQDTTKYGFDLYGKERLSELL
                     EELAKIDGFKWIRVMYSYPESITEELIQVIKKYDNICSYFDMPIQHASNNILKLMNRK
                     TTKEDILNKINLIRSNIPDAILRTTIIVGFPGETEDDFKQLVDFVEEVKFDRLGAFAY
                     SREEDTPADRLPNHIDEEVKIQRRDTLMMIQQKISEELNDKKIGKTYEVLIEEQIEDN
                     VYTGRTQGDAEEIDSIVYVKSVDNLEVGEFVSVQINDAMEYDLMGDVLYELA"
     gene            complement(92850..93908)
                     /gene="mnmH"
                     /locus_tag="KR231_000179"
     CDS             complement(92850..93908)
                     /gene="mnmH"
                     /locus_tag="KR231_000179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 2-selenouridine(34) synthase MnmH"
                     /protein_id="HBH0002599.1"
                     /translation="MSVIKIEKALKLDKVIFVDVRTEGEYEEDHILNAINMPLFKNNE
                     HNEVGTIYKMQGKHEAIQKGFDYVSYKLKDIYLQAAELALNYDNIVIYCARGGMRSGS
                     IVNLLSSLGVNVYQLEGGYKAYRNFVLEYLRHVMDTKNFVSVHGLTGTGKTDLLHLLD
                     EKGIDVLDLEGIAKNSGSTFGFITFDKKPPSQKNFETKLFESIFFSKENYIFVESESK
                     RVGSVTVPNEIFEAMTREGHHILLECDIENRVDRLCRDYIYDKDEGNILILKECINKF
                     RKRLGNKVVDDYIDLLESGEYKELVKRYLLEYYDPLYMHSVEKYKYSKIINFNDTQKA
                     LEDVIDLYESILEGESEC"
     gene            complement(93911..96322)
                     /locus_tag="KR231_000180"
     CDS             complement(93911..96322)
                     /locus_tag="KR231_000180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA translocase FtsK"
                     /protein_id="HBH0002600.1"
                     /translation="MATKKKKKKKVNTLSFNAEYHNLITIFIGVFLLYSLNSNSMGWI
                     PVLMQNLFKGLFGGLSIAIPFIVIITGLLGFFDGNEYIYRLRKTKLYYIIILFIFVFY
                     GLLNAGTLPVDSPLKGNMFDDVMKLGVSGQGSGLIATTIAYYMSKIFGIAGGWLISIF
                     ALILSVMFIFNISIKDLVSNAKSKSKASKDSNLTFKDKIANMKKSAIDMMTDEVDDTT
                     INKKPGFFKGLMSKGLNNDDEEDEYFEEENSDGVDDKTIKIVGFNKAEDEYLEILEGT
                     QSMPELDVLKELQKATNENPVVDTKPEKKVDIAKPNLNIEKTQPMSIVAEPVNEDYSN
                     YKKPSIELLNKVNKKSDENGKKKVLKNASLLEKTLSDFGVEAKINQVTVGPTITRYEI
                     QPSPGVKVSKIVNLTDDIALSLAAKSIRIEAPIPGKSAIGIEVPNEEAQMVGVREVLE
                     SEEFNNFNSPLAMGLGKDVAGKIIIGDIGKMPHLLIAGSTGSGKSVCVNTLISSILYK
                     ANPDEVKLLLIDPKVVELANYNGIPHLLIPVVTDPKKAANALNWAVTEMNRRYKLFAD
                     AQVKDVTSYNEKAEEKLPKIVIIIDELADLMMASANDVEDYICRLAQMARAAGMHLIV
                     ATQRPSVDVITGVIKANIPSRIAFAVSSQTDSRTILDMGGAEKLLGKGDMLFYPLGAA
                     KPVRLQGAFISESESEKVIDFVKSQVKDGIKYEEDIIETISKVNTSKGSDEDEFLSEA
                     IEFVVESGQASASMLQRRFKIGFNRAARLIDSMEERGIIGASEGSKPRKVLISKQDLQ
                     NLEGE"
     gene            complement(96445..97179)
                     /locus_tag="KR231_000181"
     CDS             complement(96445..97179)
                     /locus_tag="KR231_000181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease proteolytic subunit"
                     /protein_id="HBH0002601.1"
                     /translation="MKDYREDNEKFDKDNCSEESSCEERECIKQFGTNEMPPQPPKDI
                     QCITIIGEIEGHFIGNPQKKATKYEHIIPMLYSIEESNDVKGVLVVLNTVGGDIEAGL
                     AIAELLNSTSKKVVTLVLGGSHSIGVPLATAGDYSFIAPTATMIIHPVRTTGLVIGIN
                     ETFEYFKKMQDRIIQFIIRTSNIKKDVLEKLMHEKDELVSDVGSVLIGKEAVDYGLID
                     EVGGLKEALKKLRELIKESEEEKNND"
     gene            complement(97292..98515)
                     /gene="dapG"
                     /locus_tag="KR231_000182"
     CDS             complement(97292..98515)
                     /gene="dapG"
                     /locus_tag="KR231_000182"
                     /EC_number="2.7.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate kinase"
                     /protein_id="HBH0002602.1"
                     /translation="MSILVQKFGGTSVESYEKMNEVCKIVKAYKKNDEELQLVLVVSA
                     MGRKGAPYATDTLINLCSAVNDEPSKRELDLIMSCGEIISGTILANLLNAQGIDSVFF
                     TGQQAGIITSDEYSNAKIKYINPKKVKRALDDGKVVVIAGFQGVTDDGEITTLGRGGS
                     DTSAVAIGKALECETVEIYTDVDGIMTADPRVEPNAKVLSFIDYEEVFQMADKGAKVI
                     HPRAVQLAKSGNITLAIKNTMNPTFEGTKIGSLCRHLEDNIEYEQERDFKVAVANKDS
                     VAQVKIKSAEEVFTEVLNEIEKKLITIDMINFFISEKAFVVEDADIKSLKEILDKFEL
                     DYEVNRDCAKVTLICSRIADEMSGIMSKVVRGLSKAGVSLLQTSDSNMTISCLVSEED
                     MHTAVHAIHQQFYLK"
     gene            complement(98525..98770)
                     /locus_tag="KR231_000183"
     CDS             complement(98525..98770)
                     /locus_tag="KR231_000183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlmC/YmxH family sporulation protein"
                     /protein_id="HBH0002603.1"
                     /translation="MNLSEIAGKEIVNLVTGERLGVIGECDLILDETTGDILALLIPK
                     EKGFFARRKDKSFLEVPWRNVKKIGNDMIIIEYEGYI"
     gene            complement(98805..100052)
                     /locus_tag="KR231_000184"
     CDS             complement(98805..100052)
                     /locus_tag="KR231_000184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HBH0002604.1"
                     /translation="MYKTKILENGLTIIGEEIPYLKSITLGIWINAGSRIEEAQVSGI
                     SHFIEHMMFKGTKNRTSKEIASSIDNLGGQINAFTSKECTCYYVKLIDEHIDTGIDVL
                     SDMILNSKFDKNDIDKERLIILEELKMYEDSPDDLSYDLLVENIYANDGLGMNIIGTK
                     ESLYNITRESMLEYLNKYYIPNNAVISIAGNFNFDDMVEKIKSKFGHWEKKNLSIDIS
                     EAKFNPCFISKNKDTEQVNLAMCLKGIPFENDEEVYSMAVVNNIFGGSISSRLFQKIR
                     EEKGLVYSIYSSQTLYRKCGELGIFASMSTENLQDVYNLIKKEIENIRENYLTEKEIS
                     ESKEQLKGNYILDLESTSSRMMSTGKSMLLSKKVKTTDEILECINNVNINSIKKVVDK
                     VFNIENIGTCIVGRDVEKILHLD"
     gene            complement(100210..100953)
                     /locus_tag="KR231_000185"
     CDS             complement(100210..100953)
                     /locus_tag="KR231_000185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HBH0002605.1"
                     /translation="MIMMVLNKSKLKKIIILILVVLLVLSGGVMVLKLFNNKPVFNLF
                     NGVDLPYERGTKDKSGYVALTCNIDLGWETEYVESILETLKKENVKITFNVTGKWAEK
                     NKDELLKIKKQGHEIGNHGYKHLDYSTLSYEDNYEQIETSKKIIEEIIGEKTKFFQAP
                     AGSFGPETVKAAKALGYTSIKWDADTIDWKYKDQPEVIIDRMKKKDIKDSSIILMHPT
                     NATTKCIDDIIAIVREKGLKPGKLSDVFK"
     gene            complement(101219..103330)
                     /gene="pnp"
                     /locus_tag="KR231_000186"
     CDS             complement(101219..103330)
                     /gene="pnp"
                     /locus_tag="KR231_000186"
                     /EC_number="2.7.7.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyribonucleotide nucleotidyltransferase"
                     /protein_id="HBH0002606.1"
                     /translation="MFEHKIFKMDFAGRELSVEIGKICEMASGSCIVRYSDSMVMVNT
                     TKSAKPRDGIDFFPLSVDYEEKLYSVGKIPGGFLKREGKPSEKAILTSRLIDRPIRPL
                     FPKGFRNDVQVVATVLSVDQDCTPDIVAMIGSSIALSISDIPFNGPTGSVCVGLVDGA
                     FVVNPNAEQREKSSMHLVVSGTKEAIMMVEAGADEVPDEVMLDAILFAHQEIKKIVEF
                     IEGIVAEVGKEKMPVELYHAGEEITQLVREFATDKMKKAVQTFEKLERMENMDRVKEE
                     TLAHFEETLEDFEDFVGDIEEVLQDIIKEEVRKLIVHENVRPDNRKLEEIRPIWCETG
                     MIPRAHGSAIFTRGQTQVLNVATLGALGDVQKLDGLDEEENKRYMHHYNFPAYSVGEA
                     RPSRGPGRREIGHGALAERALLPVIPSQEEFPYAIRLVSEVLSSNGSTSQASVCGSTL
                     SLLDAGVPIKDMVAGIAMGLIKHDGKVAVLSDIQGMEDHLGDMDFKVAGTEYGITAIQ
                     MDIKIDGIDKEILQRALKQAKEGRIHILGEMRKTISQPKPELSPYAPKIVKMQINPDK
                     IKDVIGPGGKIITKIIDETGVKIDIEQTGEVFISGIEIDMIKKAQELINNIVVEPEVG
                     KTYKGKVSRIMNFGAFVEILPGKEGLLHISHIAHERVAKVEDVLNIGDEVEVKVTEID
                     EKGRVNLSRKVLLPKPEHKNK"
     gene            complement(103455..104300)
                     /locus_tag="KR231_000187"
     CDS             complement(103455..104300)
                     /locus_tag="KR231_000187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HBH0002607.1"
                     /translation="MKIKLVCDSLCDIPDEISEKDYIEIVPLTVIFNDREYIEGVDIK
                     KEEFYKKVKEIKQIPKTSQATYMEFKEVFDKFITEGYHIICMTGAANASGTFQSAMIA
                     KNDVNENEKIHIFDTRNLSLGSGQYVIKACELLEEGLGFEEIIDELENTRSSVRLLFA
                     PYTLDFLKQSGRVPVATALIGNMLNIKPIFFFDNGEAKLVNKVRGIKNIASKLVDIIL
                     EMNEGSLEGKIVTIGCGDNLHDCEILKDEVNKRIKARRVLFTRGGVSICSHTGPDILA
                     ISCSN"
     gene            complement(104540..104797)
                     /gene="rpsO"
                     /locus_tag="KR231_000188"
     CDS             complement(104540..104797)
                     /gene="rpsO"
                     /locus_tag="KR231_000188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002843739.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S15"
                     /protein_id="HBH0002608.1"
                     /translation="MINKSEIIKEYGRAEGDTGSPEVQIALLTARINELNGHLKTHKK
                     DHHSRRGLLKMVGRRRNLLAYLKEKDLEGYRALIAKLGLRK"
     gene            complement(104901..105830)
                     /locus_tag="KR231_000189"
     CDS             complement(104901..105830)
                     /locus_tag="KR231_000189"
                     /EC_number="2.7.1.26"
                     /EC_number="2.7.7.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional riboflavin kinase/FAD synthetase"
                     /protein_id="HBH0002609.1"
                     /translation="MVIIKSIKEIANIKESVITIGNFDGVHKGHQVLIGKTVEHAKKE
                     NIQSIVFTFANHPVNYFRPNSTKNIISNDDKIKLLEDLGIDIVVIIPFDEYMTKIPAK
                     DFVDEILVKKLKAKKIVIGHDFTFARAKEGNVNLLKSLEHEFGFEVEVIKPIKINDVR
                     VSSTYIRSLVSQGDMANVKEYLGRNYKLEGCVIHSKHLGRTIGFPTANIDLKNNMLVP
                     KRGIYASIVHIGDETYFGATNVGYNPTVNGKTLSIETNILEFDRDIYGENIIVEFLER
                     IRDERKFNSIDDLKNQLYNDTNYVYENYVCKNK"
     gene            complement(105961..106866)
                     /gene="truB"
                     /locus_tag="KR231_000190"
     CDS             complement(105961..106866)
                     /gene="truB"
                     /locus_tag="KR231_000190"
                     /EC_number="5.4.99.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(55) synthase TruB"
                     /protein_id="HBH0002610.1"
                     /translation="MNKIISILKPTGMTSHDVVSRVRKILNIKKVGHTGTLDPDASGV
                     LPICIGKATKVCEVILNKDKSYICELTLGISTDTYDASGEILKKVDDFKFSNEDIERA
                     FDTQRGEINQLPPIYSALKVNGKRMCDLVRSGRQSEITLKTRRVNIKDIKILSIKGNK
                     VMFYVECSKGTYVRSICHDIGEYLGCGAHMSFLNRTSSGKFDLDNSITLEELELFYEN
                     KTLDKYLYDIDYVLDSFNYVVLNPNAIKYYSNGGSIDDKRFLKNNFDKDDEFVRVYST
                     DNFLGLGKLSKHNNTISVKSDKMFI"
     gene            complement(106879..107184)
                     /locus_tag="KR231_000191"
                     /pseudo
     CDS             complement(106879..107184)
                     /locus_tag="KR231_000191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438308.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional oligoribonuclease/PAP phosphatase
                     NrnA"
     gene            complement(107302..>107892)
                     /locus_tag="KR231_000192"
     CDS             complement(107302..>107892)
                     /locus_tag="KR231_000192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HBH0002611.1"
                     /translation="NTNNHIGLDLGIKEFCISSCGDFIENPKYLKKSLNKLAKLQREL
                     SRKTIGSLNRNKARLKVAGLQEHIANQRNDFLQKLSTKLIKENDIICIEDLQVKNMIR
                     NRKLSRLISDVSWSEFIRQLEYKANWYGRKIVKVGKFFASSQICNKCGYKNEEVKDLN
                     IREWICPSCNETHDRDINASINILKEGLRLITIQNK"
BASE COUNT        35551 a        18189 c        12125 g        42027 t
ORIGIN      
        1 caaaacgaag aaaaattaat aaattaaaat taacgattgt aataactgta ttatttcttg
       61 ctttattatc tatatatgag atactgttct ctaatcccaa caaaaaaggt aatataaaga
      121 gtcaagaaac tatgcaaaat aaaaataata caacagatga ttctaaaaat aatcaaagct
      181 ctaccaaaaa gcaggaagat aataatatca agcctacttt ttcatattct tcaataccag
      241 ataatataaa aaataaaatg attggtaaat ctatgcctac tgatgaacct ataagctttg
      301 atagtctatc ttatttaaaa cttacatatt atggatttga tgaaaaaact catcaaggag
      361 aaatgatagt aaacagtgaa ctagctccag aagtagtgga tatttttaag gaattatacg
      421 aaaaaaaata tccaattgaa aaaattaagt taatagatga ctatgatgct gtagatgaaa
      481 aatctatgtc tgataataat acctcatcat tttgttatag aactatagct ggtacaaatg
      541 tagtttcaaa tcatggtaaa ggacgtgcta tagatataaa cccattacag aatcctcaag
      601 tttctggaaa tgatgttaca cctaaagtaa gtacagttta tgctgatagg tctagcacaa
      661 aatttggaat gataaaaaaa ggtgatgatt gttataatgc ttttgtaagc agaggttgga
      721 gttggggtgg ctattggaaa aacccagatt atcaacattt tgaaaaataa tagattagaa
      781 ataaaggtga attatatgaa tttaatgaca ttggaaaata taagtaaaag ctattctgaa
      841 aaaaaattac tagaaaatat atctcttgga ataaatgaag gggaaaaaat aggacttatt
      901 ggtgtaaatg gtactggtaa atctacctta ctcaaaatta ttgcaggagt tgaagaaagt
      961 gagactggta atataacaaa aactaatggt attaggatag aatatctacc tcaaaatcca
     1021 acttacaatg aaaattcaac tgtacttgaa caagtattta atggaacttc tgaagaatta
     1081 aagctacttg gtgaatatca agaaatccta gaaaaactta attcaaactt tacagaggaa
     1141 ttaaataaaa aattattatc agtacacgaa aaaatagatg ccttaaatct ttgggattta
     1201 gaaagtgaag ctaagtcagt acttacaaag cttggtataa atgactttaa tcaaaaaata
     1261 gcagaacttt ctggtgggca aagaaagaga gtctctctgg catcagccct tattacacct
     1321 tgtgagtttt tgatactaga tgagcctaca aaccatctag acaatgatac tatagattgg
     1381 cttgaggaat atcttaattc cagaaaaggc tcattgctta tgataactca tgatagatac
     1441 tttttagacc gtgttacaaa tagaattatt gaactggaca aaggtagatt attcagttat
     1501 gatgggaatt attcaatatt tttggaaaag aaaatggaaa gactttcgct agaagcaagt
     1561 attgaagata aaagacaaaa tttaataaga acagagcttg cgtgggtaag acgaggagct
     1621 caggctcgta gcactaaaca aaaagctcgt ttacaaagat ttgatgaact tataaataga
     1681 gattctttta aacctgatga aaatcttgat atatctgttg catcaagtag acttggaaat
     1741 aaaataatag aaatacacaa tatatctaaa tcatttgaag aaaatactgt tatagataat
     1801 ttagaataca ctttaactcg tacagataga attggtataa taggcaaaaa tggtatgggt
     1861 aaatctaccc ttataaatat acttaatgga gaaatagagc ctgatagtgg atatatttca
     1921 attggagaaa cggttaaaat aggttgtttt tctcaagacg actctcatat gaatattgat
     1981 atgagggcta tagactatgt aaaagaagct agtgactata tagaaacttc agatggtact
     2041 aggattacag cttctcaaat gtgtgaaaga ttccttttca atggtactat gcaatatact
     2101 ttgataggta aattatctgg tggtgaaaga agaagactac atcttcttaa aatccttatg
     2161 acagctccta atgtgcttct tttagatgaa cctacaaatg atttagatat tgaaacgctt
     2221 aaaatattag aagaatacct agacgaattt aaaggtgtag tagttacagt atcacatgat
     2281 agatatttct tagatagaat ttgtaataaa atatttgcat atgaaggtaa tggaaaaatt
     2341 catatctata caggtaatta cagtgattat cttatttata gagagattca aggaattgaa
     2401 tttgaagaat ctaaaaagga atcagttaaa aaagatgact ctactaccct aaaaaaagaa
     2461 aaacctaaaa atgataaaaa gcttaagttc tcatataatg aacaaaggga gtttgaaaat
     2521 attgactctg atatagaaaa actcgaatct aaaattgcaa cacttgatga aagtactgca
     2581 aaattttcaa ctgattttac taaacttcaa gaaattttag atgagaaatc taaactagaa
     2641 aaagaacttg aatacaaata tgaaagatgg gaatatttaa ataatctagc tgatgaaata
     2701 gctaataata agtaatatta aaataatctt aagtttaata agttttgctt taaatctgta
     2761 atttataaat attttaaagg aagtgtctca aaatgaactt tttagtttta tgagacactc
     2821 ttttttatga gaaatcaaat atattttcat catttcaaca atacaaaaga ggcttatctc
     2881 tattttgaga cagcctcttt cataattacc ttctaattta tatgctctaa tatatctata
     2941 ataattctta ttatatctat atatccagtc tttcaatata atgacaatta acttcaatat
     3001 gatttaaaaa tactaacaac ctttcataaa gtggatgaga ttcttctcca tatttagctt
     3061 ctaggttctt gcctatttct ctaacagtcc tttgaccatc aatttgtaaa aaaacaaaac
     3121 tggaatattc atctagttct atttttttgt atttaggtat tctagctttt aactttctaa
     3181 aaaacttttg aattttatgg tcctgttttt caagtatagt aacaactcta ttttcagcta
     3241 cttcatattc aagtccatca gtaattttaa atacaatatc taaaacatca ttactcttgc
     3301 tcattatttt ttactttaga taaaacaata ggtaatgctg taagcacaac taaaactact
     3361 aataaagcaa ttgccattga atttgttgca gcaaatccac ttggtacctt tggagttaca
     3421 actccagtta cttgtaatat tatacctatt aaaccaatga tagaaccacc agcaacaaga
     3481 ccagaagata aacttatacc attagaaact ttaacttctt tttctttttc agttttagat
     3541 actaattcaa caaataaacg aattaatgct ccaactaata ttatagaagt tgttgcaatt
     3601 ggtaaataga atcctatagc tatagtcatt attggtaaat ttaatgcata tagaactatt
     3661 gccataaata ctccaacaat aatcataacc caaggtaaac tacctgacat aataccagaa
     3721 gttaatgttg acattaagtt tgcttgtggt aatgcaaatt gtacattatc accagttgct
     3781 ctaagttggt cagaaagtaa taaaattact cctacaacaa ctataacacc aactatactt
     3841 gcaattgtaa agtaacgttg catttcgttt ttgctaccac caataatata agttactttt
     3901 tgagattgag tataacctcc agctatagca atagcaacaa ctataaatga accaaataaa
     3961 agtaatgatt tattagcttc taaatcagtc catcccatta taacaaacac taatgttaca
     4021 ataactagag aagctatagt cataccagaa actggaagat ttgatgttcc gattgttcct
     4081 gttaaacgac cagctactat gacaaataat aaagataata aaagagatat gatagctcca
     4141 ataattgcca taacaatgtt accagaaatt aagaatgctg ctaaaaatcc aataactact
     4201 ccacctaata aaagtatcat ttgtatagat gaaccttctt ctccttctcc agcacttgat
     4261 ttagctttaa gtgtttcttt tatagaagcg attatagttg gtataagttt tattgcacca
     4321 ataatacctc cacaaagcat cataccagca cctatatatt ttacataact actagatatt
     4381 gctccaacat ccatttggtt aagaggcatt gcaggattat tccataccat agctccatct
     4441 ttagccatat ctgtaaagta tcctattaaa ggtgctatac caaagtttga taaaatactt
     4501 cctgcaaaca ttgttaaaga aacttcaagc cctactataa atccaattcc taaaagtaga
     4561 ggatttactt caatatcaaa tttccatttg tagaatttgc ttcctacaag actcattaca
     4621 ttgtttgcta catttaagaa tgaaccagtt aatacagtaa taaatccact tattacaaat
     4681 ccaattccca tgtacttaat tgaatctcca ccagcctctg aagcaacaag tgtttcagat
     4741 atagccattg attctgggta cataagttta ccatgttctt caactattag atagttgtga
     4801 actatagcag caattcctat accaaataaa actccaccaa ctccaacagc taagccttca
     4861 aagaatgtaa tttggcttcc aattaatata actgctggta atacgaaaat aaatccactt
     4921 gcaacagatt ctccaccact tgacatacct tggattaagt ttttaccaag aatacccttt
     4981 gaacgagcaa atgctccaac aaaagcagaa cctattatag ctcctggaat acctgcggca
     5041 actgtaagac cggctttcat tccagagtaa gttgtagatg cggcaaaaat ggcagctaaa
     5101 ataataccga taatcagtac agctacattt ccaccggttc tggacttatc tgtgatatat
     5161 ggaacgtaat cttttccact aacctcacca taagcaccct taggtaattt tttgttcata
     5221 aaattttcac cccttttcaa tttgtatata ttataacata tatacatata aaacttaact
     5281 ttttattatt ttacaaatag cgagtcaaaa ctactaaaat ttaaccctat attattaatt
     5341 tctactttta gatattttta tgctaatttt ctttttattt ttcaattcta ctaaaaacta
     5401 ttaagatata aaataaaaaa attttttaat gtaaaattaa ttttgtaaaa aaaatgcttt
     5461 aaaacacgga aaagtataaa aaatacaata atcattctta taaataaatt ttcaccatag
     5521 taaatatata cagaaaattc ttgtttttat gcaaattgat tcttttataa aaataagtgt
     5581 cataaagaaa tgtctgaaat cactttatga cacctatcat aataaaaaat tattctggta
     5641 atgctctttt atttactttt ccgattggtg taactggtat cttatctatc ctcattatta
     5701 ttgttggaat catatatgga ggtagatgct catttaaata ttctctaata gttctttcat
     5761 ttatcttacc actatcttcc tcatcaatta cataatatgc acatatatac atatctccat
     5821 catcatttgt tctcgatata caaacaacac ttttaatttc tgtaatatta tttattatat
     5881 tttcaatctc atatagctct atcctaaact catcaatttt tacctgattg tccatccttc
     5941 caatataatc taaatttcca tcatctaacc atcttactaa atcaccagtt ctatacatta
     6001 acttattatg ttcacaagtt ttgtaaggat tctctacaaa tacttgctct gttagccctt
     6061 ttttatttaa atatcctctt gatatttgaa tgcctgatag acatagctct cctggtgctc
     6121 caattggaca tagtttgttc tttttatcta atacatatgc ataagtatta aatataggtt
     6181 ttcctattgg tatttttcca tattctctgt ccacatgaaa agaagtcgat acaacagtaa
     6241 attcggttgg tccatactca ttatatagtt cataattacg ctttctatat ccttttaatc
     6301 tttctcctcc ggtctgtaca actctaagtg aattattatt gcaattttgt ataaataacc
     6361 ttgcaaatgc tgttggcaat gctagtatag ttatgtcatt ttcctcacag tattcattta
     6421 ctgtatattc atcaaattta gcttcttcag gcataatatc tattgatgca cctacaagca
     6481 aataagggaa tagttgtttc attacagcat caaaactgaa acttaagtat ataccacata
     6541 tatcattttc tgtagcgctt atagatttta cgctataata acacatattt actaaactct
     6601 tatgttctat agctatggtc tttggcctac cagttgaccc tgaagtagat atcgtatatg
     6661 cacaatttga tgatgttatt ttttcagtta attcatatcc aagcttaaac atttcttcat
     6721 catttatatc gagtactatg gtattctcat ttacaacctt acttttgagt tcatctgtag
     6781 ttatcactac ttttgcatta ctatcttcaa gaaggtaatt caatctttct tctggattac
     6841 ttgtgtctat tggaaaaaat gctccccctg atttcataat ccctattgct gtaataatta
     6901 tgttaatatc tcttggtaac attacagcta ctatgtcttc actttccact cctatatgat
     6961 ttaaataacc tgcaagttta tcagttactt catccaattc tttatatgtt aactttctat
     7021 tttcatccct agcagctata ttactaggtg ttaccttaac ttgctcccta aataaatcaa
     7081 cataactttt atcatatggt atttcatatt gattattatt aaagtcttcc aataatactt
     7141 tttcttcttc cttacataca aattctaaat cttctattaa aatatcatta tcttctatta
     7201 tttgctctat tatataatca aattgattta aaattcttct aatagtttct cttttatata
     7261 tagatggttt atactttatt tttattttaa gtgccctctt agtatatact attacagata
     7321 aatcatatcc ttttttttct atgtcataat catatgataa atcaaaactt ttagctataa
     7381 atattgtgtt tataagctta gtatttagat gatttttatt ctctatatct gataacaaat
     7441 agtatccata ctctaaagac ctgctccact gcctttttag cttccttaca acatctataa
     7501 atttttcact ttgtctaact cttactctta ttggaattat attcattgtt ttaccaaaaa
     7561 ctacatcatc ttcatatata tacttttgaa gtataaggcc atatatagtt tctatgatag
     7621 agtctatgct aatattgttc actttagaat attgaattaa cctttcatgt ttctcaatat
     7681 tcatcttaaa aacctcatct actacttcat cagaacaatc tttataaaaa aaatcatttg
     7741 taatttttgc tatattcgta taatcatcta acaaatccat ccaataattc atagctcgtt
     7801 ctaaattaac ttcatacata tcaaaattcc cccttactac taagtctata gaaaaaattc
     7861 ttttggaatt ttattttcac aatatataaa tatattaata atacatatgc aagctctaaa
     7921 aacatgagct tgcataaaat tacacttatt atgactacta aattcgtaat atttacaatg
     7981 tttaaaatat attataacac atatatgatt ttatttttct acatttatat aatatataaa
     8041 ttacaaatag ttatttaact aatatataac aatacctttt ggaatatgat atattatatt
     8101 aattaaattt ttataagata agttatactt ataggaggga accatataaa tgaatattta
     8161 tgctcatagg gggtttagtg gaaagtatcc agaaaatact attctagctt ttaaaaaatg
     8221 tttggatatg gatatatatg gaatagaact tgatgtccac agaactaagg atggaaaaat
     8281 tgtagttatt catgatgaaa aggttgatag aacttttaat ggacatggtt ttgtaaaaga
     8341 ctttacttta agaaaattaa aaactctaaa ctcatctttt gaaggatatc aaagcaataa
     8401 agaatgtaaa attccaactt tagaagaagt attaattcta atttcaccta cagaccttat
     8461 tttaaatata gaactaaaaa ctgacaaaat aaactatccc aatatagaaa aagacgtttt
     8521 agagcttatt ttaaagtata atatgaaaaa tagagttctt atatctagtt tcaacagcaa
     8581 tagtttaaaa aactttcata aattagaccc tagtataaaa acaggattat tatgttattt
     8641 acctataaac aatgtagtca attttgctaa atttctgggt aatagttatc ttcatccacc
     8701 tctagtttta gtaaatgaat ctctaattga actttgtcac aaaaatctac ttggtgtcaa
     8761 tgtatatact gtaaatgaag agggtgatat actacactgt ctaaaactca atgtagatgg
     8821 tatttttact aactatccag atattgcttc aaatctttta cactcaaaac aatacagcta
     8881 attatacaat agtttgtact ccttgacttt tatataatta atatgtacaa ttttattaaa
     8941 tttatcttgg aggtataact atggataact tattaaatga acttgaagct ttaaagagta
     9001 atttagataa tctaccaata gaaaaaatag aaaattatga tttgagtaaa actgctttat
     9061 ttataattga tgttaataat ggctttgcaa gacaaggtgc attatactct cctagagtag
     9121 agtctttaat aaagccaatt gaaatgttta caaaaaaaat atcaaacaaa ttaaatagag
     9181 taatagcatt tactgattct catactccta aatcaataga acttttgagt tatcctgttc
     9241 actgtttgga aaatgatgta gaaagtgaat tggttgatga acttaagtcg atagaaaacc
     9301 tacaaattct tcctaaaaat tctactaatg gattttttgc attagaaaat ttggattttg
     9361 ataatataga taatataatt atagttggcg attgcacaga tatatgtata tatcaatttg
     9421 caataactct aaaatcatat tttaatcaac ataatattga aaaaaatata gttgtaccta
     9481 tgaatttagt agatacttat gatattccta acgttcaccc tgctgagatt ttaaacttag
     9541 tatttttcaa cagtatgatt caaaatggag ttaatgtatt aaaagagatt cgttaagctt
     9601 ctaatacttt acatcccata taatacaatt atcagatatt tatttttaat aaaatttcta
     9661 atagaaaaac acagttttag tgagaagatt acaatttaaa acactatcta ttattactaa
     9721 tcttcacaat ataaaaaatc gcagtttaga tattccttat acaaatttat aaggaataat
     9781 aaattgcgat ttttattttt aagtagtaca attaatttat actacttcag tatttaaatt
     9841 cattttttaa taatcatact tattcgtagt ttcgcacatt actaccttta tttttttatt
     9901 aaacatattc ttatattcta ataaaaactc atttagttct gaatccataa gatttatttt
     9961 tctatcacta caaagcatta tcttttcttg gtcgattatt acattaatat catttaagtc
    10021 attttttata aatgttgtta tacaactctt tggttggatt ttttctccat atttctcata
    10081 aaatcctgca ctcttcttaa atgactctaa atcttctgta gatactttgc tggaagtatt
    10141 attactcata aaacctgctg tagaagggtc gattccaaag tttctaagtt gtttttctac
    10201 ttcttcagtg tccataccat atctctccat aaattgcttt tgtattttca taaatttttc
    10261 ttgagatatg ttgttatctc tcatataatc gaatattttt cttgaaaact cagccataga
    10321 catctttcca tccataacag aaaaatataa gttatatatg tattgctcaa atttatctac
    10381 atcagaatct ttaactttgt tctttagttc gttaaagtct attattctat catcagacat
    10441 ttttcatcct cctagctaaa tttttacttg tataagatta taccatattt ctattatatt
    10501 tatatacaca ctattttttt aatttaacga ttttttctgt agcatctaat tcgcacattc
    10561 tgcccaaagg aatagttatc attgggatac aatgtcctga ctgaagatta tatatagaag
    10621 gtttattgac cttatttgca aattctatta gtaattccat caaatcattt tcttcaatac
    10681 aatccttaaa atctccaaaa attataccat tacattcctc aagttttcct gaagaatata
    10741 gttgtgttaa cattctatcc agtttatatt gaggttctcc aatttcctca ataaacaaaa
    10801 ttttatcttt tgcatctatt tcatattttg ttcccattgt ggcaattatt aaggataaat
    10861 ttcctcccat tattattccc tctgctttac cttcacatac agtataaatc ttttcttctt
    10921 ttggattttc taaatataat tcatctttaa attctaaagc atttaccaat gatttatagg
    10981 taaatttacc ccatttacct acatttgctg ccattattcc atgatatggt aaaagaccac
    11041 aatttttata gaaagctaaa tttaaacctg ttatatcaga aaaacctata aatggttttg
    11101 gattttgctt tattatatca taatttattt tatccaatat tcttgttgtt ccataacctc
    11161 ctcttaagca cataattata tctacatctt tatctaaaaa catatcttct atatcccttg
    11221 ctctaatatc atcattacca gctaaataac ctttataatt taaactacaa ctttcagaaa
    11281 acttaacttc gtaaccataa ctttctaaat taaactttat ttcctccaaa cttgtatttc
    11341 ttaatggccc agatggcgca attattccta acatttaaac acctcttctt ataaaatgat
    11401 atattcttct ccatactaaa tatctctaat ataattataa gatattttat ttgtacttga
    11461 tacataataa tgatttacat aaaataatat aattaatgaa gaaaaataaa tttttaatat
    11521 agttaggatg tgttttatgc ttaatataaa aactctttgt catgagataa atgattgggt
    11581 tataaatata agaagagatt tacataagac tccagaactt ggattagaag aatttcaaac
    11641 taagaaaaaa attattaaat acttaaatga aataggtata aattatattg aatataagaa
    11701 tcatacaggg ataactgcat acattaacgt gagtccaaac tttgaaacag ttgctataag
    11761 agctgatata gatgccttac ctataacaga agaacttaat tattcttata aatctattaa
    11821 tattggcaaa atgcatgcat gtggtcatga tgcacacact gctattttac tgggtacttg
    11881 taatatacta tttaaattaa aggattactt aaatgtaaat gtaaaattct tttttcaacc
    11941 tgctgaggaa actattggtg gggctcaact tatgatagaa gatggatgtc ttgaaaaacc
    12001 aaatgtaaaa tatatatttg gactccatgt aaatcccaat atcaacaaaa atctaattga
    12061 attaaaatac aacactctaa atgcttccac caatacactt caattaactg tacatggttc
    12121 aaaatgtcat ggagcttatc cacatcaagg tattgatgct attgttatat ctgctcatat
    12181 tattacagct ctacagacaa tcgttagtcg aaacacaaat ccaactgatt ctgtggttat
    12241 ttctctagga aagattgaag gtggaatcaa agaaaatata gtttgtgaca aagtggttat
    12301 aaggggtact ttgagaacct tgactcctga aactagagag ttttcaaaaa aacgaattag
    12361 agaaatttgc gattttactt gtaaaacatt tggaggaagt atttctgttg aaattgagga
    12421 aggttatcca gctcttatca attcaaacca tctagtagat tacgtcaaac aaaatgctgt
    12481 agaattgttt ggtgaagaaa atattatcct taaagactcg cccactcttg gtgctgaaga
    12541 cttttcgtat tttctaagac actgtgaagg agctttttac caccttggtt gtgcaaatcg
    12601 tgaaaaaaac attacttccc ctttgcatac ctctactttt gatattgacg aagattgcct
    12661 tattactggt gtcatgctcc atgtaaaaaa tgtattatca ttctaactat taatattttt
    12721 atttattatt ttatattgac cctcacatga tgtcatgtta taccctaaaa ttacaaatga
    12781 taaattaaat agttggaggt aatattatga aagaaatatt aataaatcct ataggtaaaa
    12841 tatgtattca aggcgaagag gtctttatta aattagacaa aaagtatgta cctgcattaa
    12901 atgaactcga cgatttcagt catttaaatg tattttggtg ggctgatggg tttgataatc
    12961 ctgaactaag aagtatttta gaaaccccaa aaccttataa aagtggacca gacgttatag
    13021 gaatatttgc aacaaggtca cctataagac ccaatccaat agcattgact gctgtacaaa
    13081 ttatcaatat cgaccatgaa aatggcataa taaaaatacc atatattgat gctaatgata
    13141 atagtcctgt tattgactta aagccatata ctccaagcgt tgatagggtt gaaaatccgt
    13201 ccgttcctaa atggtgtagt cactggccta agagtgtaga aaaatcagga gaatttaatt
    13261 gggaagatga aattgaattt taaattactt ttttcttgat ttcattaact tgttttccac
    13321 atttatttta tttacactta ccaagatttt atgtcacata tacatataat attaggctgt
    13381 attatataat acaacctaat attatataat aaatttctat ttttccctta aatcattcac
    13441 attctttcta agctacataa gatttttcta ttatttcttt ttgagtttaa tttagcatta
    13501 tgttgaggaa aaaacatttc atgcatttta ataaattaaa tttttctttt attctgcgat
    13561 tttataataa tcaatttaac ttaaaaataa tacctaacta ttttaactat gttaaactag
    13621 taaatgtaac cacttatatg ttacaatttt atataaacat caaatataaa aaactatata
    13681 aataaatgac acatagtgtt atattttttt ataccaattt agttattttt cagttacaga
    13741 tttaataata gttaatagta agacataata tttttatgcc ctttattgat tatgtatttt
    13801 ctgttatctg ttattatcat caataataaa cataaggggg tatatattat gaaattgtat
    13861 ttaagtgctg atatagaagg tacttgtggt attgtaaatt gggatgaaac aaaacttgaa
    13921 tgtgaatttt cgcaacacta tagaacgcaa atgagtaaag agataacagc agcatgtgat
    13981 ggagctactc aatctggtgt acatgaaata cttgttaaag atgcacatga cagtggtaga
    14041 aatattaatc caaatatttt acctgaaaac gtcaaaatac ttagaggatg gaccaaagac
    14101 ccactagtta tgatggcagg aattgatgaa agctttgatg catgtatatt caccggctat
    14161 cactctggag ctacttgtaa tggtaatcca ctttctcata ctatggatat tgattatgac
    14221 tattttaaaa taaatgatga aatagcatct gaatttacta taaatgctta tattgctgca
    14281 tattataatg ttcctgtagc atttttaagt ggagatgaaa tgctttgtga gagtgcaaaa
    14341 aaactaaatc caaatatagt cactgttcct gtgtcaaaag gaattggaaa tggttcaatt
    14401 tcaatccatc caaaccttgc actaaaaaaa attgaaaaag gtgtcaaaaa agctttatct
    14461 ggagatttat ctaggcactt aataaaattg ccagataaat ttaagataga aataaaattt
    14521 agagaacatt ataaagcttt taaggcctct ttttatccaa atatgaaaaa aatagattct
    14581 caaacagtac tatttgaaac agaggactat tatgaatttt taagaatgtt attatttata
    14641 taaatttcat atcataaatt aaggagttga ttaagataag taataaaaga aggattcctt
    14701 taggcgaatt tatttctgta tttttatttt ttgctgtttt ttttggtata actttttgta
    14761 ttttcacggt tataggaatt ggcttcttat cattcttagg atttgaatat aaatctcttg
    14821 gagctgtatt aattttcttt ttaatatatt tttgtataac cactccaatt gattttctat
    14881 gcactactat tttagatata ttcagatatg taaacaaatt accatactca atatataaac
    14941 tttgcgaatt tataattgat tttatactaa cttttctagc tatgaacata attgatacct
    15001 ttatggattc agtaacgatt cctttaagta cagaaatctt attcgcttta ctttcttatc
    15061 ttttatcaga atgtatggat ttttttgata gggataagaa aaaaccttaa taaaaaagat
    15121 agattcctta atagaacaca tattttcgta tttctattat ttaatctatc tttattttat
    15181 ttaataaatt tttattaatt aaaatatagt ttcttctatc tccttagtca tttgcttagc
    15241 actatcaaaa aattcttcta tatacactac ttcatcactg accctagaat attctgctgc
    15301 aaatgccatt acatgacttt gtatagcttc ttttgctgct actctaccct tttctagttc
    15361 tttatttgaa actaatttaa taaattcagc tataagattt ctatcatatt cctctaccat
    15421 attctgttga tttgatggat tcataactat ttcttcgttt tttccaaatt ctttaattct
    15481 tatctcattt ttatttaaat ccccaccaac ttcaccatgg ctaaacatta actttatagt
    15541 tcttccattt tctttagtaa atgcacataa attaaaagta gccgtcactc cattttcaaa
    15601 ctgtagtata tttaccatat tgtctacaac attattatca catctgtaaa cacatcttcc
    15661 atatggactt gtcttaagta tattcaatag attctcttca gttggattta tgtgaacagc
    15721 tctatttata cttctatctt tttctaaata aattctcttt gctgaatatg gacatttttt
    15781 ttcaactaaa cactgaagac aattttgtgc catctctcca ctagcatttt ggttattaag
    15841 atgctttaag cttccaaatg cagatatttt tttgcatcta cttcctacta aatataacaa
    15901 aatatccatg tcatgacaac tctttgctaa aattaaaggg ctggtttcat tgctatttct
    15961 ccaattccct ctagtaaagc tatgtgcaaa atgccaatat cctatatttt cattatattg
    16021 tatactaact agctctccta attttttgct ttctacaatt tcttttaatt tattataaaa
    16081 tggagaatat ctcagtacat ggcaaatcat aaaaatctta tctttatact tatcacacaa
    16141 gtcatctata tgtaccagac catctaaact attagacatt ggcttttcta atagtacatg
    16201 ataacctttt tcaagagcta gttttgctac atcataatgt ctatcatcat ttgtagctat
    16261 tattactgca tctgccatct tgtcatgttt aaaaaagtct tctaaagttt caaatacatt
    16321 tttactatct aggttatatt tttgtgtaaa tagttctcgt cttccttttt taggttctgc
    16381 tacagcaact atttcacata catcagaatt ttcataaata tatggagcat atgcatacgt
    16441 tcctctatta cctgctccaa tcacagcaac tttcactttt tccatacttt aatttatccc
    16501 ctttatatta tttatactac tctattatag tctattttta cagacatttg gatattttta
    16561 ataaaagaaa cagcagttat aatttttcaa ttttaactgc tgttataagt taatatacca
    16621 aacattttta attaaatttt ctttaatttt aatacaaaga cttaaatatt aaatacaaat
    16681 tataaaaaca cttttatcta gtttacttct tcttttcttt gtctaattta tctaacttct
    16741 tattgtataa aaacatataa aatgctgccg aaaatactat taaatatcca acaacactta
    16801 acatatctgg atagacattg aataagaata tacttaaaat tgctgaaaag attatattac
    16861 tatagtcaaa tatagagatt tccttagcag gtgcatattt atatgctaga gttattccaa
    16921 attgacctag acttgcaaat actccaccta gtaatagata tataagttgc ataagggtca
    16981 ttggttcata tactgcaaaa gcaattggcc ctacagtaac taatgaaaaa actgaaaaga
    17041 aaaatacaat tgtatagtaa tcttctctat ctccaagaac tcttaaacaa gtatatgcca
    17101 ttgctgcaaa tacagctcct gcaattcctc caagatatgg aattacttct acactaaatg
    17161 ttggttttat tatgaataaa gctcctataa atgcaattat aatagctcct atctgcttta
    17221 catttatttt ttcttttaga gcaattgcac aaaatattac tacaaggaag ggactcattt
    17281 tatttagcat attagcatct gaaagcatca acttgtcaat tgcatagtag ttaaatataa
    17341 ctcctagagt tccaaatatt gacctatata aaagtacttt taaattttct tttttaccag
    17401 ttagacttcc tttatgtttt atgataagcc aaaaagctat tatagctgat accagatttc
    17461 taaagaacac tttttgaaaa cttggtaaat ctccagctag ctttacgaat gcagacatca
    17521 ttgcaaagcc aagcgctgat gctattataa acattatacc ttttattcga tttgatttga
    17581 ttgtgctact catacgtacc tcttttctat ataaatgtat aaagccatat taattaaaaa
    17641 cttagcttat acattaaata ataattatct aaatattcca atttatacta taattaaaag
    17701 tgtaaactat gtcaagtaac taataaatct tttcaattaa taacaataat aattatagct
    17761 aaaaagttat atgtttttat ggattattat cagaatatat aatataattt tatatagtat
    17821 agactttttt taatttatta tttagatttt taatagattt tttaactatg gaggtattta
    17881 aaatatggaa ataaagagat atgaaggaac tggaagaatg agtagagctg tagttcataa
    17941 caatacagtt tatttatgtg gacaaactca tgctgaagga ggagtaattg aacaaacaac
    18001 tgaagtttta gctaaaatag aagatttatt aaacaaatat ggttcagata agcaacattt
    18061 gctatctgtt actatttatt taagagatat gaaagacttt gaagctatga actctgtttg
    18121 ggatgcttgg gttgaaaaag gatttgaacc tgctagagct tgtgttgaag ctagacttgc
    18181 tagagagcat ttgttagttg aaatgagcgt tgttgcagct acaaaataat caatttagct
    18241 tataggaggc tatctcaaaa cagagagata agcctctttt tcattgttga aatgatgaaa
    18301 atatatttga tttcgtataa aagaaagtgt ctcacgaact aaaaaattca ttttgagaca
    18361 cctcctcact atttaatcta tataaattta cttattctct attggcaata tcaatttaga
    18421 tggatattta cctccatggt aaatcgtatt ctttgcttct atatattcaa tactattata
    18481 tccctctgtc gtgttgctat tttggaaaat aaagttttta gcactagacg ttatatctag
    18541 tctaatttta tgaccaactt taaacgtgtt tgatattttt gaagttataa tcgtaaactt
    18601 ataaatctct ccttcttcca taaactctga cttataaaaa ctatttctaa atctagcact
    18661 aagtatacca tcagctaatt taattgaatt tccatctaaa tccacgtcca taatttttat
    18721 aacccagtca gtatctttgg cagaacttga tgcaaaaaac tctaacttta tatcacctgt
    18781 tacagtaaat tcttcactaa aagcatctga tgtataacac aacatatcac ttcttttttc
    18841 taaatctttg tagttatttg gaactccaac ttcattctct gacatatcaa ttagttgtac
    18901 tgatgggtct tttggattat atatataact atcatacttt tcttctaaat cattatcaaa
    18961 tactaatcta ccatttccta aagatgtgtt agcatttcca tcacttatta gatacatact
    19021 tttatctatc ttatttatta ttggccaatt ttcttctgtc ttccacttat tagaacctac
    19081 agagtaatac tctactggag cagtcgtatc tatgttattt tctatacctt ttaagtattt
    19141 atcaaaccat aatagataat tataatccaa atcatatctt aatgaactat ttcctaaaga
    19201 aataccattt atatctctta aagtatttga attatgcatc catggaccta gaatagcctt
    19261 tctctttcct ttttcatagt cctttataac atctaaggcc tctgtagttc ccatactatt
    19321 atcatcatac cacccagata caaccaatgc aggtacattt attttatctt tttgtaaatg
    19381 ccagtccatc aaatcccaat actcatcttt ttctactctc tttaaccatt cttccagaaa
    19441 ttcaattcta tatccaagag cttcaacagg tatattttct attggtcgta tgtttaaaac
    19501 atcatcccaa tcatctctta ccattttgct tctatcaact ttatttcttg ataccataaa
    19561 tgcccatgca agcataccag atacaaaagc tcctcctttt cttggtatat caataaaagg
    19621 gcttcctgat gttactatac taactaaagc tttaagatgc ttattgcctg aagatgcagc
    19681 tgcccattgg acataaccaa gatatgatgc tccaagcatt ccaactattc cacttgacca
    19741 ttcctgtgat actatccaat ttatggtact atctccatct tccctctcat gaatcatagg
    19801 ttcccactta ccttctgatt catttcttcc cctaacatct tgtattacaa cagcatatcc
    19861 tctttgtaca tatttataat atatttcttt atcattttct tttccatatg gagttctcat
    19921 aagaattgtc ggtgcttttt tggcagaatc tacaaaatca gggagatata catctgtaga
    19981 aagttttata ccatctttca tatcaatcat ataatttcca ccaaatctta tagaatatat
    20041 ctcttcattt ttatgagttt tttcccattc ttttaataca gtatactctt catatccatc
    20101 cataattaat atagtacaag tttctctaga taaacagata aaacctacta ttttattatc
    20161 tacaataatt atatctagtg ggaacttttt gtttctttga acccatatat attcattaag
    20221 tttagaatgc gtttctccta agttatttat aactgtgtct ttatctgtgt ttactaagct
    20281 tttagtatat acatcaaaat tattaaataa agactttaaa tctatttttg taagatttaa
    20341 ataatatgta ttttcttctt tgcttattgg ttttaaactt tctattttat ttgtaaaagg
    20401 attcaacttt tcaattaata aatctccatc aaagattaca tttccactgt atagtccaga
    20461 tatgtataat ttaaatttta tcaattaaac tcccccctat aatcctagag acatctttat
    20521 tgcatatgcc actgatatac ctgcataatt tcctaatact ccaccaatta ctcccattac
    20581 gactgctaca cttacaagcg aattccactt tgcagaagca gctactaaag ctgaagtagg
    20641 accatcagca attgctccta ctatagaaag tattacatat tgatacttta tctttaaaag
    20701 tctagttatg cctaaatgga aaacaaatga agcaaaaatt atactaaaac agtaaagtgt
    20761 tatagtaaaa gttgaaccta aaaactcttt tatatctact gaaaaaccta ttgtacataa
    20821 aaagaataat gcaacaaata atcctaaatc taaatttccc tttagtttct ttactggctt
    20881 taattgagca attataattg aaattgttgt aactaaaagt attcttgctg cactactaaa
    20941 acttgaattg aaatatccag caagtattgt tgaaacttct gtaacaacaa aacctatagc
    21001 caacatccaa gctatatctt taatactcca ttcttttgac tccataaatt cttcattttg
    21061 acaatcttct aattctgatt cttctacatg atatggccaa agttttttaa acttctttga
    21121 attttttaat attgctggta gagcaaacat aaatatcaat gttggtactc caattacata
    21181 gtctgctgca tttgctgctg caagagtttg tctacttaca ttaagacctg ttccaatagc
    21241 tgtaagatta gcacttccac cagtatatgt acctacaaac attccagcaa ccttccaacc
    21301 ttctgatatt ttttctgcaa atactaatcc aaataaaaat gccatgatac ttacagttaa
    21361 tacagctaca aaaattgcaa ttaaaggttc tcttgataat tttgtcattt cttttaagtc
    21421 aacactcatc aacattatag tcatagaaat tggaatagca tatgttgaaa tagttccata
    21481 taactcagta cttactggaa ctacttttaa gtttgaaagt attattccca ttatgattat
    21541 tgtaagtgct ggtcctaagc ttttaatggc tttgtatctt tgtaagtaaa aacccaatgc
    21601 aatcattgat gtcattacag caagtatact acctggattt gaaaaaagtg tattcatatt
    21661 taacctccaa atttatcata agtttacttc tattcctaaa cctggtttat tgacaagatt
    21721 cataatatct ccatccatta caaatcctcc agatatacct tctaattctt cacaaaacat
    21781 aaaactatca aggtcagctt ctgttatgtt ctttttagat gctattaaat ttgctgctgc
    21841 tgttatacca attctcgttt ccagcataca tcctaacata caatttactc cacttgcctc
    21901 agctatgttg ttgattttta tagcaggata tattccactt gatttcatca gcttaatatt
    21961 aaatgtatca actgcattct tttttatagc cttaattgca tctattggtg aatgtaatga
    22021 ttcatctatc ataatttttg tgttactttt atttcttatg taagcagtac catctaaatc
    22081 ccaatgtgga agtgcttgtt caattgcatc aacattaaat tcttctaact ttttgatagt
    22141 atttatactg ctatttacgt tccatccttg atttgcatca attctaattc ttatactctc
    22201 tccaacggct tctctaatta actttacagc ttcaatatcg tcttcaggat ttatacctgc
    22261 tttaagcttc aatatcctaa aaccttcttt tactctttct aaagcttcta ctgccatttt
    22321 ttctggctta tctatactta tagtaatatc cgtttggact ttactatcaa atcctccaag
    22381 aactttataa agaggtgcat tcataatttt tcctttaata tcatataaag ctatgtcaat
    22441 agctgctttt gcagaagtat tacctataat aattccatcc atgatggtat gtatggtttc
    22501 aatatctagt gggtctttgc ctattaactc ttttttaaac ataagcaata ctgaaagaac
    22561 attatccaaa acttcacctg taactgctgc aagaggtgct gcttcgccaa atccacaata
    22621 cccttcatca gtttcaattt ttaaaattat actttctcca tactcaatta ctccaaatga
    22681 aactactaca ggttttttta atttaattct aagcttttca aatttgatat ctgttatctt
    22741 catattaccc tccttatttt ttgaagttat aattcaattt ttaaaatttt atactttaaa
    22801 ttatattatt acttcaatat atatgtcaag ataatttact gaaaatttac tcttttccaa
    22861 aatataatgt gataatctta attcaattaa tactcttcta ttaaattttt ttattattat
    22921 tttctttgta ttaatttaac aataattcat tttcatagac ttttatttgg atttaattaa
    22981 attttaattg tcaaaatcta ctatgtattc ttattgccac tacttctatg ttgtgctata
    23041 attactttgt tttaagcgaa tattttatat taattttatt atttggaggt tcttatgcta
    23101 ggtgaaaaga tgagaaatat aagaaaaagc aagaaaaaaa cattaagtga tgtttccaaa
    23161 ttgacagatt tatctataag ttatatctct caaatagaaa gagatgctat tgaaccatcc
    23221 ttgtcttcat tgagaaaaat cgctgaagtt ttagacactc ctttatatat gtttatggat
    23281 gacaataata ctgatgattt agtcattaga aaagaagata gagttatgat gaaatttcca
    23341 aagagtgaaa tgttttacga gatagtatct ccaatgccta caactgagtt tacaccttca
    23401 attttatttg tagagtttga acttaaacca gaaagtgagg atgccaaaga ttatatatat
    23461 catgcatcag aagaaattat ggtggtaacg agtggtgtgg ttgatatttg tatgggtgaa
    23521 aaggtagtta gattaaatcc aggtgactca acatttataa aagctaatgt accacataaa
    23581 atcatcaatc caagtaaaga tacaatagct cgtggatatg gagttatatc acctccaatt
    23641 tggccaataa aatctaaata aactcaatat gacacaccta ctttttgtag ataatataat
    23701 agatttaaat attgctttta ttttaaattt aaaatattta ctcaaactaa aaaaatagct
    23761 atttgactaa tctaaaccat cttaattatg gtaaatagta aatagctatt tgtaagttat
    23821 attataaatt ataataaaaa ttgtatttgt taaaattaaa ctgctatatc atttaatact
    23881 tttgccttta caactcttat atttttcata ctcttgtaga tatcttgaat cttatcttct
    23941 tgctctctca atagtctatg tgcttcatat atatctacaa gttcaaattt tactacatca
    24001 tttggctttg cttgtgctaa cttatacaaa tctacactta taacgttccc tatcttagta
    24061 tagccaccac tagtctgtct atctgataac attataatcg gttttccatg accaggtact
    24121 tgtatagctc cataagaaat accatcagat ataatatctg ctccattaag gtgctttata
    24181 ctctctccat ctagtctaca acccattcta tctatttcat tcgtaacttt gtatttattt
    24241 gataaaaatt tctctacttc accgttagaa aaagcatcaa attgaggacc ttttacaatt
    24301 cttagtacga tttctgaact ataagttgga atatattttg aacttaattt tttatttatt
    24361 gtaaaatctt tttcctgaat aaaagtattt atataatctc cttttttaag tgctctacct
    24421 tcaaatccac caattttagc tcttgtataa gttgacttac ttcccattgc aagtggaaca
    24481 tctattccac cagctattga cacataggct ctagcacctg atttcacacc tctaaatgat
    24541 aatacatcac ctggatttat ttgatatgac ctccagtttt gaatttcttt tccatttatt
    24601 ttagccccta aatctccccc agttactgct atttgcgtat attcatcaaa ggtaattgta
    24661 ggacctaaca ttaaaacttc taaagaagcc tcatcttcag aatttcctac taatatattt
    24721 cctactctat gtgcatactc atccattgct ccacatccag atacaccata ttgaccatag
    24781 ccaactctac ctctgtcttg tattaatgtt tggaaacctc ctaattcaac tttgaatccc
    24841 atatatacca ctccctgtac tataacgata tttaaatact taagttattt ttttcgattt
    24901 ctataaattc atctaatgtt attggaacaa attttataaa atctccagct ctaagcaaaa
    24961 tctgttcttc tctattttca tcatataatt ttaaaggtgt cctaccaatt atttgccatc
    25021 caccaggact atcaatagga tatacaccag tctgggaacc tgctattcca acactcccac
    25081 cataaatttt agtccttggc acttctaatc taggtgtagc tattctttca tccataccac
    25141 ctagatatgg aaatccagga gtaaaaccta gcatatatat caagtactct ctgcttgtgt
    25201 gtatttttat aacttcatct acagtgagat tattgtagct tgcaacgttt ttaatatcta
    25261 taccaaaaac ctcatcataa catactggaa tctcatgtat tttaggtttt ggtaatacta
    25321 tactttccaa attatcttct atttttttta aattctcaat caaactatca aaatctattt
    25381 ctaatggatt ataacttatc ataagtgacc tatatgttgg taccatttct gttacaatac
    25441 ctttaagatt cgatatttct attgctctca taaatgaaat tacttttttg tttatatctt
    25501 ctgatatctc atttccaaat tcagcaacca ctgccttatc ccctgatatc aagtatctag
    25561 tttccataaa tgtcacctct tctaaattaa gcaaataaag cacctaggct gctaagagaa
    25621 gttattcctg tatatgcaga tattaaaact actattaatc caaatattaa aagccatgta
    25681 ggatgcttgt aatctccaac aatatctttt cttttagatg ctataagcat aattcctaat
    25741 gtgattggaa gtatcaatcc atttaaagct cctgctaaaa ttaataaagt agctggtttt
    25801 cctataaatg ccattataag tgttgatatt gctataaatg ctattataaa atatttttca
    25861 tatttatcta taaaaggatt tagtgtcttt aagaaagaaa ctgatgtata agcagctcct
    25921 ataactgatg taattgcagc agaccataat acaagtccaa agaatttata tcctattgct
    25981 cctgcactaa atttaaaagc tgaagcagct ggattttctg ggtcaagttg aagacctttt
    26041 gaaaccactg ccagtattgc taaaaataaa agaactctca tcattgtggc aactaatata
    26101 cccaaaagag aagatttagt tatttctttt atattttctt ctcctgttat tccaccgtct
    26161 attaatctat gtcctccagc aaaagttata taacctccaa cacttcctcc aagtagagtt
    26221 attattggga atatcagtcc ttttggattt tctggtttta ccattcttga tactgcctct
    26281 ccaacaggag gatgatttga tattgctaca tatccaacta taattatcat tcctaatgct
    26341 aaaaatttag ttatcttatc gactagagaa tttgaatttt ttgacataaa tacaaatatg
    26401 gctattaatc cacttaatac agttcctaat gtcatattca tattaaacat tacattcata
    26461 ccaagtgcag ctccaccaac atttcctata ttaaaagcta atcctccaag agctactaaa
    26521 aaagctacta aataacctaa tcctggtatt attttatttg ctatatcctg acctctaagt
    26581 cctgatacac caattactct ccatacattt acttgagccc ctataaaaag gattgttgta
    26641 attaaaatta caaatgaaaa attcggtcca aaatcttggg taaattgtgc agtctgagtt
    26701 aaaaaccctg gtccaattgc tgatgttgcc attataaatg cagcccctat aagtgctccg
    26761 acatcttttt tatttttagt tttatctgta atattttttg tactcatatt ttatctcccc
    26821 ctcatgttat cagtcttata ctatgttctc tgacgaacaa acttctatgt tttctaatgg
    26881 acaaacttct atactttcta attcaaaacg ctttcttatt tctttgacaa actctattgc
    26941 ttttggattg tccccatgta cacatataga atctgctttg atatgtataa cttcacctgt
    27001 taaagtttct acagttcctt cttttaccat cctaacaacc ctatctattg catgttttgt
    27061 atcatgtata actgctcctt ctacatttct tggaaccaaa aaaccattat tatcataagc
    27121 tctatctgca aatacttcat ttgcaaacct aagtccaatt tctttagcag aatttatcat
    27181 ttcactatta tatagcccca acagtataat atctttatcg acttcatata tagcttcaca
    27241 aatccccata gctaactctt tatctttagc tgccatattg tataatgctc catgtggttt
    27301 tacatgttgt atattacatc catttgaact tgcaaatgcc attaaagcac ccaattgata
    27361 ttttgtataa tctttagctt cctgctttgt tattttcatc tcacgtcttc caaatcctat
    27421 taaatctaga aaacctggat gtgcgcctat tttcactcca ttttttttag ctagctgtac
    27481 tgttttttcc atatgactag ggtcacctgc atgaaaccca caagctatat tagctgatga
    27541 aatatatttt aaaacttctt catctaaacc aatcttatac gttccaaaac tttctcctaa
    27601 atcactattt aaatctactt tatacaattt atgacccctc cttgctaaca ttttgataga
    27661 ataagtagtt ttaattttta aattttgttt attttatata ttgcatgaaa tattttatca
    27721 cttgtattca attttatttt tgcaactatt ctattgcatt taattaatat aattttacca
    27781 tttaaggaat atttttgcaa ttattttaat tgaacattca tttgtatttc tttttcaaaa
    27841 aatcttttta ccatttttta gttaataatt aattattttc acttaaaata agggctttaa
    27901 cctttatttt taaagtattt ttcattttta atcactttat atgcaagaca gaatcatttt
    27961 tcttcattca tttgtttctt tcatctatat aattatcatt ctttgtaagt aaaatatctt
    28021 tatattttta taattaattc tttatatagt tttaagtata ataaaatcat gtatactaaa
    28081 tgcatgttaa aatattattt taaaacatgc acaatatttg tacatattgt agacatataa
    28141 acctataaat tatacaatag tattgttaag attatatatt tttttaacat aaattttgta
    28201 ttgggggaaa aacaatggat aaaaactata cgatgccaat ataccaaaaa atagcgttgg
    28261 atattgcaaa taaaatatac acgggtgaaa tacaagagga ttcagtacta tttggacgct
    28321 ctgttttggc tggtaaatac aatgtatctc cagaaacgat aagaagatct gtcaaaattt
    28381 tagaggacat tggcgttgtt aaaagcataa agggtaaagg tgttattgta ctatctccag
    28441 acaaagcttc ttcttttata aaaaaatata gagatattac aaatatatca tcatataaat
    28501 caacacttta taatttaata gatactaaat ctaatttaga aaatgaaata ttagatacta
    28561 taaataaaat tttagactat tctaacagac ttgaaataat caatccttta gtgcccgttc
    28621 agttcaccat aaattctaat tgcaaatata ttggtcaaac agctgcacaa actaaatttt
    28681 ggcaaaatac aggtgctaca atagttgcaa ttaaaagagg tgaagaactt ataatatctc
    28741 ctggaccata tattgaattt ttagaaggag acattctctt agtagttggt gaccaacaca
    28801 tttacaattc tataccaatg tttttatatg aaaacgaaaa ataaattata taatttagta
    28861 tgattatata aaaatgcaaa attaacaaca aaaaaagagc ttcatatttt acataaagct
    28921 ctttttaaat tcaaataaat ttaactttga ttaattttta aatatccaat tcatcttctt
    28981 tttcccagct taaagctctc gatacagctt ttttccatcc tttatataat ttacatctct
    29041 tctcttcact catatttgga ttaaactctt tttctactga ccactttgaa gtaatttcat
    29101 ttcttccaat atagaatcca acagacaacc ctgctaaata agcagctcct aaagctgtag
    29161 tttctactat tttgggtcta tctatatcta catttaatat atctgattga aattgcatta
    29221 aaaaattatt attacttgct ccaccatcaa cttttaatga ttttagtttt aattttgaat
    29281 cgttttgcat tgcttctaaa acatcctttg tctgataagc aattgattcc aatgtggctc
    29341 ttactatatg ttcttttttt gctcctcttg taagtcctaa aattgaaccc ctagcataca
    29401 tatcccaata tggagctcca agacctgtaa atgctggcac tacatataca ccattagtat
    29461 cctctaccct atttgcatac atttcactat cttttgcaga ttcaattatc tttaattcat
    29521 ctctaagcca ttgaacagat gctcctccaa taaatatact tccttctaat gcatatgtta
    29581 cttttccatc aactccccaa gcaattgttg taagtaaccc atgcttagat ttaactatgt
    29641 tactgcctgt attcataagt aagaaacaac ccgttccata agtatttttt gcagtacctt
    29701 cttcaacaca attttgacca aataatgctg cttgttggtc tccagcacat cccgcaatag
    29761 gtattttagc tcctgataac atgcgctcat ctgtatgacc ataaacatag ctagaaggtt
    29821 ttactaatgg caacatgctt attggtatgt ccaattctcg taatatatcc tcatcccatt
    29881 ctaaatcatt tatattgtac atcattgttc tagatgcatt tgagtaatct gttacatgta
    29941 cttttccacg agttaaattc catattaacc atgtatctat agttccaaat aataactctc
    30001 cttgttctgc tttttcccta gctccttcta cattatctaa tatccatttt acttttgttg
    30061 ctgaaaagta tgcatctatt aaaagacctg ttttttcttt tattgattct tccaatcctt
    30121 tatttttaag ttcatcacat atttctgacg ttctcctaca ctgccatact attgcgttat
    30181 aaataggttt accagtatac ctactccaaa caaccgtagt ctctctttga ttagttatcc
    30241 ctattgaagc aatttcttct ggtcttatac ctgctgtttc tataacttct ctcattaccc
    30301 cactttgtga cccccatatt tccatagggt catgctctac ccatccagct tttggataaa
    30361 tttgattgaa ctctttttgt gcaattttca ctatttcgcc ttttttatta aatagtatag
    30421 ctcttgaact ggttgttcct tggtctaatg ccattacata cttcttttcc atcaccatat
    30481 tctccttatc atataatatt taatttatta aaaagaaaaa tttaatatca catatttcaa
    30541 taaataatca tacttaagta caaatttaat ataatagata tttagtaaga agacacttat
    30601 tttctatcat atctatataa taatattata cattatagct tacatattga ttaataaatt
    30661 ttaaaggagt ataataaaca gtgttcataa taattttaat aaaagaggtg gtaatatgcc
    30721 aaagatttta gaaaatgtaa aagaagatat attaaaagtg tctcgggata tgattttaga
    30781 agaagattac tcgaatatta gcataaggaa aatagctcaa aggtgtggta taagtgcagg
    30841 tacagtgtat aattacttta attcaaaaca agaaataata gaatatatca caaaatctga
    30901 atgggattta ttgataaggc gaattgaata ctccaataaa aacactgaag attacataaa
    30961 aaaactaaac attattttta ctgaaataag aaattttata aacaaagttc ataatatcca
    31021 atacaatgac tttttaaaca cttttgaaac agagagattt tttgaaatga aaaaacacaa
    31081 agacgacttt catgaacagc tttcaaataa agtatatgaa gctttagaaa aagaaagttt
    31141 ttttaataat gacaaattag tatgcaatat cataataaaa atgttttttt catattcaac
    31201 atatcttcat atagaatttg aagatttaaa accctatatt gaaaaattaa tacattaagg
    31261 tggtgtttac cttgaatcat aatactagta ttaagaacaa ggacagtaat ccaaaaatat
    31321 ttttagtact tacactttat ctattaggta tatttatggg agctattgat actggaatag
    31381 tatcaccagc aagaacgatt atacaaaata gccttggagt aaatgaaaaa acgggaattt
    31441 ggatgattac catatacaca ttaacatacg cttctgtaat tcctatctct ggaaaattag
    31501 cagataaaat aggaagaaaa tatgtgtatc tagttagtat atttctattt ggtagtggtt
    31561 cattaatatg tggattatca tcactatttt ccaatttcta tattttatta attggtcgtg
    31621 ttattcaagc aattggtggt ggtggaatca tgccaattgc tacagcagaa tttggaacta
    31681 ccttcccaga aaacaaaaga ggcatggctt taggtttagt tggggcaaca tatggtattg
    31741 ccaatatttt aggttcaagc attggtagca caattctaag tatatttgga actcaaaatt
    31801 ggaagtggct attttttgta aatcttccaa tttgtttaat catacttatt ggtggagttt
    31861 tctgtattaa aaacaataag tctgaatcta aagaaaaaat agataagctt ggtacattga
    31921 tgttgatatg tataatcgta tcactattat atggtcttat gaatatagac ttttttaatt
    31981 ttaaaaattc tatacaagat atatcagttt atccatattt attgacattt attgtactta
    32041 tacctatttt catatttatt gaaaatagag ctaaagaccc tattttaagc tttgaatatt
    32101 ttttaaatcc gagaatattg atagtactta ttttatcttt aattgttggt attggaatga
    32161 tgggtatggt attcgttcca cagtatgctg aaaatgcatt aaagataaat gctggttctg
    32221 gtggatattt tgtagctata ttgggattat ttgcaggtat tgctgctcct ttaagcggaa
    32281 gacttattga caagtttggg gcaaaaaaaa tactattact aggattttct gtatctatga
    32341 taggctctct ttacctagtt ttaattgctc taaaaaccaa tactgtattt agtgtatgtg
    32401 taagtttaat atttatggga ttaggaatgg gatttactat gggaactcct ctaaactata
    32461 tgatgttatc aaatacaaga ttagaagaat ctaattcagc acttgcaaca ttatccttga
    32521 tacgctcaat tggtacttca atttctccag ctataatgat tggatttata gcacatgcag
    32581 gattatctgt gcaagataat attatggact tagttggaaa gccctcaact cctaaaatag
    32641 ttcaacttga agaacttgaa aacatgatag atgacttaaa atcagaccct gaaatggcaa
    32701 aaaatttaaa aaatgtctct atcccaaata tgaatgatac ttcaaatata aatatggaca
    32761 tgacaggtgg caaacttcca aaatccttac ttaataaagt tcagtcagca gatacaacca
    32821 acattaccaa tataacaaaa gaaatatcaa caacaatgtt tgatgaaaaa gttccatcta
    32881 taattactaa aatacagaaa aatgtacaaa aaggaataga tggaacacaa agtggaataa
    32941 acggtattga agatggtgaa aataaactaa atagtggtat taaaggagtt caaactggta
    33001 ttgacaatat ggtaaaagct agagctggta ttaatcaagg aatagatggt gtaaaaaaag
    33061 gtattgctgg tgttgacaaa ggtataaaag gtatggaaca aggtcttgaa aaacaagatg
    33121 aggccatcaa ggaacttaca actgcttata ataaaatacc tactacagaa aaaactccta
    33181 ctgataacga aaataactca aacgaacaaa accagagtaa taccagtaat tctgaatcag
    33241 atgacactaa gaatgattct acagaaaata agaataacaa ttccagcgag aataaaccaa
    33301 atgtaaatga acaaaaagaa agtttaaatg ctcaaataca gcaactaaaa aagacaagag
    33361 atgacttaaa tacaaagtta caaaaaaata aaactcaaaa gaacgaatta agtaaaaaac
    33421 taagatcaat ggaatctcaa aagaaagagc tacaaagcaa gttaaataat tctataagcc
    33481 aaaagaaaga catggaaaaa agccttgata caatgcaaca gcaaaaaaaa tcactccaag
    33541 cagttttagc aaagacacaa gaggtaaaaa ctgaaatacc aaaggctttt gataaatcaa
    33601 aattggatta tataaattcc atagaaaata atagaacaaa aatagaaaac acactacaat
    33661 ctactctaaa ctcaggattt aaacagatgt atataacagt attctgtgta aatctactag
    33721 catttataat attattgttc tataaagaaa ataaaactag ataaaagagt gttatagtat
    33781 tatattgtaa atttatctta ttcttaaata ttttattcta aagaataaat tcataaaatt
    33841 tttgtaattg attaatataa attacaatat aatactattt ttctcttaat ctttttctct
    33901 tttacagaca atcaaaaagc aatcttagtt tatcgaaata aatttataca atctattcat
    33961 acaccccttt acatttatat aacaattaaa cctattgtta tatatacaaa tcaaaataaa
    34021 ccatatattt tcaactataa tatgttaaaa tcatattatg agcatattaa tttaagcaaa
    34081 atgtcattta gactttaatt tagtagtttt atattataaa tttatatatt tttaatttta
    34141 aatgtcattt agacattact cataaaaaga aaggagtgta ttttgtggat actttaggaa
    34201 aaagaattgc ttatttgaga aactccaaaa aacttactca gcgcaaactt atggatattt
    34261 taaaatttga aaacttaggc aagtatgaaa caggagatag aaaacctaat tgtgatatac
    34321 taatgtcaat agctgattat tttaatgtta cgactgactg gcttctctat ggtaaagaga
    34381 aggtaaatgt caatagtagt gtaaaagaag ataaagaaga ttacttacat gttactaatg
    34441 atgaaatgac gatattaaat ctatacagac aactaaacga acgtgataaa ataaaaatag
    34501 aaggaatact tgaacttaag atatctgaat ataaagactt aaaaaagcat tcctctaata
    34561 ataatgaaga taaaatggtt taaacataca taatttgata cgattttaca tcatctatta
    34621 accttctttt tttgtagtat attactaaaa tatggatatt ggattattta aaaacaagta
    34681 tagtctaatt tcaagcacat ttataatatt tagattatct tatccatatt ttagtttaag
    34741 tactttgaaa aatataatac atctctatgt ataacttata ttcctaagaa atgcattact
    34801 catgttttta attcttccaa catctttcta tacacaattg tacatccttc ataattcccc
    34861 tctttaagaa ggattgaaca tgtactagaa tatttagtta aagtatttaa tctttccata
    34921 tttaagcttt ttatattact gagtgctgta ataaaatcat caattgctct acaacactct
    34981 ataaccccat ctgaatccaa tttacacaca agaatattca cctactttat atactattta
    35041 ttaatcatct tctgaatatt ctatattaag taattgataa attgatgatt tatatttttt
    35101 acctgttctt cttccattta aaatagctga caaatagttt tcattaacac ctattttctt
    35161 cgctaattcc ctttgagtca tatttaattc aataagtctt tgcttgactt gcactcccaa
    35221 aaaaggtatc catttttttc gagcatccat ttatcaactt cctttctaag cgatttatat
    35281 ttacttttat attattttag cttacgcacc ccctctattt agtatatatt tttaatatgt
    35341 acacatatta agtatataaa tttatttaat actaaataag attttttgat tactttgtgc
    35401 taaaattagg atgtaaattc gtatcattaa gttaattata aagtcatttt gaccttaagt
    35461 caatggtttt tatgtcattt tgacctttaa tttgaaacta tttacatctt aaaaagtctt
    35521 tttgacatta attgaatgga gagtgtttat ggatacttta ggagaaagaa ttgtttattt
    35581 gagaaaagca aaaaacctta aacaatatga actagaagaa atgttgggct gtgacaactt
    35641 aagtaaattt gagagaaaca ttagaaaacc aaattatgaa atattaaaat ctatagctga
    35701 gatatttaat gtttcagtag actggctatt aaatggagat aatctatcac ataaatcaga
    35761 tttaatttgc gattcctcct caaactatcc acttaatagc ataaactcta atgaaataaa
    35821 gcttttaaac aattttagaa aattaaatga ttatgataaa gctaaaatag aaggtatgat
    35881 tgaattaaaa cttcatgaat atgaaaaaga gaaggattta ggaaaaattg agtataacaa
    35941 aaataaagat gagaaaatag ataaataatt tttatgttgc ttttgatacg attttacatc
    36001 atttctttgt tctaatattt ttatttcatt tattttcttt tttataattt tatgataaaa
    36061 taattagtat attttgcttt acttgaatgt aattatttat acaaaagtca aacataatat
    36121 aaatgtagta aatttttagt ttcaagtaat atctcgttat tataactaaa tatttattaa
    36181 aattaggagg ataaaatggg cttaagagac aaattcgcgc aatcatttgc tagatcaaaa
    36241 actatgagtg gccctgagaa aaaggctaat gaaataatgg gtaaattgct tcttaagaaa
    36301 gctatattac ctatcgtttt aatgttcgtg ataataatcg ctggagctat gcttaaaatc
    36361 aattcttggg ttacacttgg cataaattta gttattgctg ttggtgcttt cttctacata
    36421 agaaattcta gtaaaaagta tcagaacttt aaaccttatg ttggcaattt gattagttta
    36481 gagaaaaaag gtaaaaaaga gtacgttgct attataaaac aaggtaagtt accagttaag
    36541 ttacaaatag cttatggtgg tgaagacctt gaacatgtta agaaaaatca aatggttcaa
    36601 ataagttata atccagatgc taaaatagct attttggtta atagacaata atttaataaa
    36661 aaaaaggagt tgtcttaaaa ttgatttttt ctaatcaaat ttaagctcaa ctcctttttt
    36721 aatttttata tgttattttt attacttttt ttaattaata ttttaaatat taaatccttc
    36781 tcaataaaat agtgaactat ctacaatact actttatctt ttcctaacaa tatataatct
    36841 ggtgctactc tttcatgtta tacaccattt tgtaacatac cttttatatc agtaacatct
    36901 tccttaattt cctctacatc tgttttcatt atacccattt gaacaagtat atttttgttt
    36961 atttcttgtt gttgtgtaga taattctata aaattttcta cagttttttt atacatgtct
    37021 ctatcttctt ttttctcctg catagtattt ttaaataata gagcacatag tatacctatt
    37081 gcccctagac tactcaattc ggttattaat ttatccatta tagcctccta ttgtctaaat
    37141 tttttatact tatagcttta atttttgttg tattcttaca tcatgcaata ttatattttc
    37201 aggattatca atttaatctt ctgtacttta aattgtaggt gtaatttata gattgaataa
    37261 ataataaata tatatacaag ttctaatgta acaaaaaata agtacaaggc ttacttatta
    37321 aagttaagac cttgtacttt acataaaaaa aataactaat acatagttat tctaaattta
    37381 ctattcaact ggtatttcta attctttaca tctaattcta acttgctctc taattactgc
    37441 tggtacttct tctattgttt ttttgcctct taaaattaaa gctacatata cttctaccat
    37501 tccactctca cctccagatt ttcttacact aaaagtgctt atattacttg cttcattgac
    37561 agaactttga tttaacaaca tctcatatat ttctacattt gctataaaat tatttgttat
    37621 atcatcatct tgctttactt gacctatact tatgtctgaa atgtctttat actgcatttc
    37681 tacttttcta ccttgtttga tttgttctat tttattttta tcgaatttaa acaattttca
    37741 cacctccatt ttaagcttgt ggctcgttgt tttcagcatc atatctaaaa atcatagatg
    37801 gacgttttat agctgtccat ttatctcctt tttctactat gattttaggc tgagcacttt
    37861 ttatgttggc ttcttctaat tcatagattt cttggtaact tgagtctgat tttttgattt
    37921 caactagttt catgtctttg aataagtcag atttatttat ttttacttga actttagttt
    37981 tatttattaa ttgatatata ggattgtttt ccatcatatc atcctttaat ccctcattta
    38041 atgttactat taagtcagtg ttattttcag taatgtttat gattgaatat actttattgt
    38101 ttatcattaa aatagaatcc ttttttactt taagccctgt ttctgattta aatataaaca
    38161 tacttgaata taaatcgcct gtaggactac tggctttaat cagtatctta ttttctccta
    38221 atactatttt attttgtggt atctcaaata taatgctatt tatttccaaa ttagtcttag
    38281 tagatattaa ttcatcattt ataaacattt caagtttttc tataacatta ttagggtctt
    38341 gtactacaac tctcacttga gatattgatt tttcaactat ttctatagat gctttacttg
    38401 tatctacttt tgttatcatg tatattgtat catctgaaag ctctatatct aaaatatcat
    38461 ttagatgttc aggaattggt attttagtaa attcatataa atcagtaatt gatatagata
    38521 ttttatacat agatttattt ttaccagtta tccatagact attatcattt ttaattacta
    38581 gtatgtggtc atcattatgt gacttaattt ctttaacatt agttaatact ttagtaaaag
    38641 ttcttattat cttatctttt tcactttctc ctagtccaaa taatccattt gtattgtacc
    38701 cttgagcgta caactctccc tcattagtta aaacaagtgt cattgagtta tatatactta
    38761 tatctttaac agaaggtaat ccagtaacct tttgtaactc tcttacatca ttattgtggc
    38821 caactcccaa ttggtactca gtattctttc catatgacca tagagtatta tctgtcttaa
    38881 taatatagga gtagttatct ccacaagcaa cttttttgac atctgatata tttacttcag
    38941 taagagttaa taattctata tcttcaaggg tttgattaat ttctttatat gaattacttc
    39001 ctattccata taacttgcca tccttagcaa cagccaatga atgtgttttt gatatatcaa
    39061 tatcagatac ctcaaatggc aatattattg aagtatactt aaaattatct ttaaatatgt
    39121 ttttataatt tatatactta ttatttgttt ttatatactt atcattaaac attactagct
    39181 tttcattttt cttattaaaa actattttat ctgatgtgtt atctgtttta aaatatgaat
    39241 gtagggaacc ttcaagagct tcatttttat cattatcata tctatggtga atacctaaat
    39301 gattatatct attatctcct gttgaagaat aaaattttcc atatatatct ttaataaata
    39361 tagtattgta actagaaaat acagtatcaa catctttctt tatagatact ttataatatg
    39421 gaactgacat atccctataa gattcatcag atataccata agtatctcta cctgatgata
    39481 tcaaattgtt attattatct atataaagtg tattattagc tgttacaaaa acatctttaa
    39541 catcttccac actatttgta ttattattat ttgctatact tccatatcca ctaagacctc
    39601 caacaaatag tttattgtca tttgttaaaa tggctgaagt atatccatta actactattt
    39661 tttttgcatt tataatatta ttaattactc gtatcccctt tatatcatta gtctctgttg
    39721 aaaagaatac cctctctttt ttccctgtag tataaatcat attgtcattt gttataaaaa
    39781 atgtagcttc acttcctgct gtcacaacag attttacatt ctcaatattt atttttgtaa
    39841 atgtacttat acttccttca gtaaacccaa aatagccatt tacaagtcca catacatagc
    39901 atgtattatc atttttaaca atgattgata catcattaca tagatataca tctctaacac
    39961 catttatagg tatacgtgta aatatattcc tacttgtagt atcacccaat cctaactgtc
    40021 cttttccatt attacctgct ccatataaaa gaccatcatt agttaataat agagatgtgt
    40081 ttccatatac agctacatat tttacatttt caacatttat tttagtaaat atatttctat
    40141 ttacattatc tcctattcct aactgaccag aattatttaa accaacagca taacaggtat
    40201 tatcattttt tatcgcaaat gcatgtttac tattgtcagt aaatctattt acatttatag
    40261 attttatatt atcaatattt attttagtaa atacctttct atttatctca tctcccactc
    40321 ctaattgacc tacatcattt aaaccaacac tgtaaagcat attattatta gttaataaat
    40381 atgtagactt tgaatggcta tatatttctt gtatattaga agatatttca ctactgctat
    40441 tctttttatt gtaatttatc ttattattta aatttaaact actattaact gatataccat
    40501 gcgtaccctt agagttatat ccacatataa ataagctctt atcagttaat attgcaaatc
    40561 tagttttatc tctacttaaa tcataaggag gtataaatat attttttata tttttcatta
    40621 cctttttata attagtggca ttatatccat cttgtgtatc tgaaacatct agttcttttg
    40681 cactttcaga tatattccca aaaccatata gcgtgttaga agataaatac aatagagctt
    40741 tatataaaaa tatggcttta tcagaggtaa taggacctga atttatatta gatgctgcaa
    40801 tattattaga tgattgattg ttaagataat tccttccata ttgatgtata taagatgaac
    40861 ctccagaaat aagtaaatta tctggattga cattttttaa attacttgac gattccccat
    40921 tatataaata agcaaaagtt gtagaagatg atgattgtgt acatcttgta ggataataat
    40981 tatatatata agaatcaaga tatcctgcat atgaaattcc ctgatattga actctatagc
    41041 ttgaatcagt tggttttgtc catgaagtac catggtatcc agttagaaaa gatccaatgt
    41101 ttgtacaaaa tacagttaca tactcatata tgataatatt attaatttta gtaatattat
    41161 tcgtgcatga aactctacta taacttgacc ctgatatatt tatataatac caatcactta
    41221 ataaacctag atttacatta gatccatcag aagtactaaa acctaacagg taatttgtat
    41281 ttataccagt tgcatatacc tttttttcat caactacaat aaatgttgca ttatatgaac
    41341 tataagcatc agttacatta ctaaggctaa tctcagtata ttgacttatt aatgcattac
    41401 taagtccatt aacataactt gaactctttc cagaagtgta tatttgctta ttattagtta
    41461 caattaatga aaaccagttt gataaatcag tatttataac aacttttttt acattatcta
    41521 tagatatttt cttaaataca tctgaattag aaggaagaac acctgctatt gagttactat
    41581 ttggtccaga ataataacaa gtatcatcat ttttaatgta gaatattcct ccagaaatat
    41641 tttttgatgc tactatagac tttacattag agatacttaa ttttgtcaac tcatttaatt
    41701 gacttggtaa gtcagaaccc attcctttgt atctattatt tcctagacca tatacatctc
    41761 cattccctaa aataaccaga gtacaataag gactaaaaac gacatctctt acagaatgta
    41821 tatctagtgg aagttcaata tcctttattt ccatttcttc ttttaataaa gttaatttat
    41881 cctcagattt aattaaattt atataattac tataactata tttttcacta tccattttct
    41941 taaattctac aatgtgcata tcatcaaaaa acgaacctaa ttgtccataa gtattatctc
    42001 ctgtacaata tgaatcatta tttgaatcaa ttagtatgct atgtgataaa ccaatgaaaa
    42061 tattcttagc tacaatattt tttaaatcta taaatgaatt atctatattc tcagagtaat
    42121 ttgctatacc taactgatat atatcattat ttccagcaac ctttaaagta cctttgttat
    42181 ctataagcat agtgttacca tgaccacatg caatagtttt tatatttact tcttctatct
    42241 tagtaaatag tgatgattga agtgcatttc caaaacattt ttcctttcca caaccatata
    42301 tatcattatt atacgtcatt aacacagtgt gttcagaacc acaagctata gtcttaacat
    42361 cattaataga aactaaacta aataaatctc tattattctt atctcctaaa cctagttgac
    42421 cttgattatt aaaaccagta gaatagcatt tattgtcatt ctttattata aaagctgatt
    42481 tattatatga aaatacagcc tttacattgt caacatctac ttttgtaaat gtatttacat
    42541 ttgcagatgc tccattagtt cctagaccta attgaccata caaattattt ccagcaacat
    42601 ataaagttcc atcattgtat aaaagatatg ttgattgaag tccacatgca atatccttta
    42661 cgccttttat ttctggaacc ttctcaaatg tagaaactgt tttccctact ttttctaatc
    42721 ccaatcccat ttgaccatct gtatttatac ctgcgacaag taattctcca tctgaagtaa
    42781 gtataactgc atgagattct ccacatgcaa cttttttaat attggtagat atatttggta
    42841 ttttcgtaaa taattttctt gttgtattgt cttctcccaa tccaagttga aagttactat
    42901 tatctccaca tccatacaag atattattat tttttagacc aaatgtatag ttacaacatc
    42961 cagtaaaaaa attaataaag tcataattat catacccttc atcaaattca tcaactacca
    43021 tatttttatc gccaaagaaa ttacctcttt gaagtagttt agttcttttc attataaaaa
    43081 cctcctaatt atcttatttc atacgaatat ttatttaaag ttatatctgt ctgaccaatt
    43141 gaatatgccc tattagattt tgtttcaaca aagttattat ccatttcatg tatatatcta
    43201 actctatttg cattaaatgg tagcaccaca ttcttaaatg taacactacc aagttctcca
    43261 gttatacact ttctatttaa atctaactta aggccttcta tagctattat gtttttagca
    43321 ttagttaagg tatcatacca atatccagct tcatctacat ctatttctga ctctaattct
    43381 aagtatatta agatatctaa tactttttca gataatttat tgtaactatt ttttaataca
    43441 gatagttcag tttgtatttg acctcctatt acatcatcaa tagatatatt tttaattttt
    43501 tctactacct catttatagc tcctgataag tttttagctt ctgtagataa gagttcttcg
    43561 ccaattttta cttttatttc ttttatattt ttatcaaact tatcatctaa atcttgaata
    43621 tccttttgag ttacaaaaac caacgtcggg tctacttcta atgtaacatt tgaagtattg
    43681 gacaattgta aaatcatttt tacaaccaaa tctttaatac tgccatcttc agcacgtggc
    43741 ttatacgtct ctggatactt acctatagct attatattat tctcattatc cagaacagca
    43801 gcttctctta tcataaatcc accaactgtt cctggtaaaa tagtctctat aactatccaa
    43861 ttaggatttt tttcatcaat tcttagagaa tttatatttc cttcccaaac tacattcttt
    43921 aaagcagttt gttcctctgt tggctcataa tattctccat tactatctcc aacttgaaac
    43981 ttggttaatc caacaagctc tcctagtgca gttgcatttg ctattttttc tctaccaatt
    44041 ttggttaata ttatataaaa tttttcttcc aattatacca cctccgattt aggataaact
    44101 actacatttt ctacacctgt atcatttgca atagctatat taatcttaca attattttca
    44161 atgcatttaa tgcttaaagg ataaaccttt atttcttctc tacttatcat tccagctcca
    44221 cagtttacaa cagcactaca ttttataatt ggttcaaagt atggatgaac ttttacctct
    44281 tcactacata ccatacctcc accacaatag accatacttt tatctagtat tattggttct
    44341 aaatagtgta ataagtgagc aggttttact ctttcaatca tatcgctaca atctaaaaga
    44401 gttttatagt cacagttatt tgctataaaa ctcaatacga atgtaaattc atcactataa
    44461 acttttatat ctgtttctga ttttgtatat gcctcacata tactttttat aacttcaata
    44521 gtactagtac ctctgcttct cattttagct tttatattgc tacgtcttgt gtcaaaatca
    44581 agttcttttt tttcaatgca gagtatgtct tcccacatat ctaatcccca tgttgcagtg
    44641 tcaacaaata attggttaaa ggtatcatca atatcttctt taagaatatt taattctgta
    44701 tcgtatgcac cttgtatctc ctctacaatg taatttctat caaatgatgg tagtttatca
    44761 attagcttca ttgattttcc acctcactaa aattaacagt tgttacacta ggtattttat
    44821 cttcattaat agttatatta tctgtacttc catttataag taggttactt aaatcgtgta
    44881 caccagtagt atttataagt attcccatta cttttgtata gattatctct cctctaatat
    44941 ctctaaagta tgtatttata ctttctagga aagattcttt tacattgtct aatgtatatc
    45001 catcttctag tttcattact gcacttatac ttatttctat tggtaatggt gtcacaactg
    45061 ttatagttgg tccaataggc ttctcttcat ctatatgttg ctgacacctt tcaattgttt
    45121 ctgtatcaac agcttgatta tttttcccaa atatcaagac cttaactgtt cccggaccat
    45181 cccatcttgg ataaacctta acattataga ctccatctac ttccaaagcc cattcttcat
    45241 agtgagcttt atttccactt gtagcttgat ttctttggat tttataaaat ctttctttta
    45301 gttcttcatc tgtctctata tctgtaccac cttcaaaact tcttgtgtta gtaatctttg
    45361 ttactccaga tatattatca actagtttaa attcacaatt tgtaggtaaa ttatatttct
    45421 taccaacttc cagagcttga actgggctat tgtcaccttc ttcactacca atagttacat
    45481 cttttattac tacaaatagt aaatctctat atgatattat tgtgccatta tttattacag
    45541 tacctttctc tccaataaat tcaacttctc catttgactc tgtacctaac tttctatata
    45601 caccaaattc attgactctt ttatcaagaa actggttata tgtgtcttgt ataaaagcca
    45661 ttttatgcat ctttgaaagt tctagatata tcttcgaaag ttctagatta tttccagata
    45721 ccatgttgtt tagaaaagaa ccttctcctt tataaatatc aagattaata ttttcaagag
    45781 ttctattttt tattacttca tatgtctggt cactatacat ttatttccac ctccccatag
    45841 atagtggata cttttacatt tgcactcaat atgtctctgt taaagttagc actttttacg
    45901 tttacttcta atatatatgg atttattaga agggcctctt ttatgaatct actagcttca
    45961 ctttctgtaa gaccttttgt atatttttgt cctattagtt ctgaaagctc tgtcccatat
    46021 tctaaagagt atatctcatg ttcatatcta tttgtcttta tacacttgta tatccaaact
    46081 tttaaggctt cttttttttc aattatttta aagtcacctt tttctaaaat aggttcatct
    46141 ttttcaaaat cccatgccac ttcacgaaag attggcaatt cttctgtttt aggtaagata
    46201 taatcctctg ggacacctat aaaaggaaat attgtactca ttataagctc accaacttac
    46261 ttacaacagc aaatttttcg cctattctaa acattattac catatcccca gattcaaagt
    46321 tatctataaa aggatttttt acttcatgct ggtgttcttg atttgtttct gtgtcaaatg
    46381 tttctagctg tctatcaatc atccaactat ctatcaaaat atcttctttt tctaatatga
    46441 tgttatttgt ctctattttt aaatctggta atttactttt aatttttcca ataaaaaaag
    46501 aaggttgatt atgatacttt ccttcttctc ttattattcc tataaattca tttattggat
    46561 tagccattat atcaccatcc ttttataata ctctcctagc tgtgttaaaa tctcttctac
    46621 tacttaactt acttatttta actacatcac ctttttgtgg agcatgtaaa aattctccat
    46681 tacctatata taatccaaca tggctgactg gattatgaaa aaatactaaa tctcctgctt
    46741 gaagattttt ttgttctact ttcttgcctt ttttagattg ttgatttgac gttcttggca
    46801 aactaacatt aactttttta aaacaataga ccattaaacc agaacagtca aaactacttg
    46861 gtccatttcc accccattta taaggtttac ctagatgttt ttttgcttct gatattacta
    46921 ttttagcttt atcagataca ttaccagaat aaccaccaat aataattttt ccttttcttc
    46981 ttccaaattt actagcttct tcaacatttc caaataaaat atctatatgg tatgttccat
    47041 tcttttctat agttattgca ggtcctacgt catttacttt atagactcca tcacgaccag
    47101 aaactcctgt aattacctgt atttcatctc catagtttaa taaaggatgt ttatttaaaa
    47161 actcttttgt ataataagtt tgctcatatt taccaaccat aggagcagcg caagtttttt
    47221 tagatgggtc aagttttttc tttctacaat ctgtatctcc accttcttct tttctaggac
    47281 agtaagctgt aaattctgct gtaaactctt ttcctcctgc ataatcttct ccccctaaat
    47341 tactttcttc cttaggttca tcctgtcctg ctgacttttc atccataaga ttttgaaaat
    47401 taagttcaag ctcaatttga tattctccat tttgccaagt atgtttgtct gtatctatat
    47461 aaaatagtcc tacaagcttt gtataagaat ctttaacttt tactcctcta ccagttatac
    47521 aacttacatc tccataacct ttaagagaac agcttttttc tatcccatta aactcgctat
    47581 caatatctac atcttgattt tcttgttgct gaattacttt ttgcattatt acatttactt
    47641 ccttaaaaat ttcattatct attttttcgc taatcttgct tccatactgg tctaccacta
    47701 ttactttatt ttttacattt tccatgctct ccgaaaaggt ggtatttata atattaaatc
    47761 cctcttcaaa cataacactt aatgtaacag ttcctttttc aataacatta aacttatcta
    47821 aattggcctc tatcatatac tttttctttg tctttttact tgcttctgta tatgcactca
    47881 ttattgtgtc ataaccattt actcctataa acatctttgt atacttgaca ttggtctttg
    47941 ctattattcc aactgaaagc ctattttcag caaatacttg ctttgctatg tcttcaacta
    48001 acttatcttt aaaattgtat gacacttcac tttgtgtaag taaaaatccc atatctttag
    48061 atacaaaact aatttcatta ctgcttgaat ctttagacct attaattatc attcctctaa
    48121 agagttcttt ctcatctaca tagaaacaga ctgtactagc tattggtata tcgatttgtt
    48181 ggaaatttac atcaaatgat gattgtatta ttgaaaactc tagtgtcctt gatggagatt
    48241 tataatcacc tgaccatgat accttgtcta ctatgtcagt tatgtcatat atacttccgt
    48301 tttttatgtg tacccaaatc ttaataataa aaaatcacct gccttttcat ttaattctat
    48361 cagcagttat ttataactta ttatctataa tagttattgt tttggagtta cttttggtat
    48421 ctttattctt ttatactctt ttaaatctaa tgtaaaatat acatctcgag tcccatctct
    48481 ttcttcataa ctaaaccctt caattatgac ttccatattt atatttgttt ccgtaattgt
    48541 aaatcttaat ataaaacctt ccttcatcca tttttctatc ttatttacac aatcatatgg
    48601 tgatggaaaa cctgtatagt cacagaaagt atagtcttta tttggaaaaa aacttgatat
    48661 tgaaatgctt ttaagagcta caccaccaaa agttgctatt tcacctattt tgagtatact
    48721 agaagagttt acagcagctt ttccattaat actaaaggaa gatggaaata ctggaaatct
    48781 aaatctatct tcagcttgtc taagccacat ttccattata agacaccccc taactgtgcc
    48841 aattggatac ttgcaactaa ttttgatgtt atcttttcta tatcagcttc ttctctaatc
    48901 actattgtat cagctaactt agctatgttt atatttccac cattttttct gcttctatat
    48961 tgatttgctt cttgtttagt taaaaccatt tcaccttcat ggagtctggt ttgatagtca
    49021 ttataaggaa catagttcaa tccaaatgca ttattacctt tcttacctga ataagcttta
    49081 ccagaatcac cagcctttgt tccagcatat ggattatctt tgtaattttt tttactcttt
    49141 tccactagat ttaaaactgt tcctgtgatg cttccatttt ttatcttatt aatcatagtt
    49201 tgccaccatt tacatatatc tttaactatt ttacatactt tatctaatat gttaaaaaaa
    49261 gctcccaata ttggctctat aattttccat ccagtttcca acagaggtcc taaggtctcc
    49321 catacagttt tccaaataac acccagtgtc tctataaaat tgtttatttg aggtgcatat
    49381 tcacctaaaa aagtaaaaat tcttgtgata ataggactaa cagcttcaac tacaggtccg
    49441 attagttgga atgctgtagt tactattgta ccaaatatac ttattaatcc ttgtgcaatt
    49501 ggtgatttat tgtttatact atctagtaaa ttatttacta agtttactac tggaagtaat
    49561 gaatctatta atgctgtaaa atcgatattt tgtaatagtg tacttcctgc gttaacaatt
    49621 gcttttggtg cattccctat cattgttgct gcatgatttt caaaacgttc ttgcttattt
    49681 tcaaccatca ttttacgctt ttcagcctca ttagaaattc gatattgagt agaatcagaa
    49741 aactcttttc cattttttac acttctagat tgcatctggt catatttgtt gccaataatt
    49801 atcttaccat tcattacatt gcctatttta ccagccattt tttcagataa gccagctaaa
    49861 ttgcctaatc cactttctat aaaagttttt attttcttta gtccttgacc taaaatatca
    49921 tcaaaaggtt taacaatact cttcaagcca ttgttaatgc ttgtttgagc tcctgatatt
    49981 atacctggta ttgtattact catttcttta gctaacccca tctgctttac acttatgcct
    50041 tccaatgctt catcaaaagt tttataattt tctcctacca gagtattaag agattccatg
    50101 tttccttttg ctgcacttaa gaaagctgct gatacatctt gttcactact tgtattcata
    50161 tttaaagctc taacatctac catagcttga gttatatctt tttctttttt gccaccagta
    50221 atattactaa tcattttagc tttagttccc attgcaacaa catcttcagg gtcaaaaggc
    50281 gtatcatttg ccattcttac taaactgcca taataatcat caacatctat ttgattaact
    50341 tttccagtat ttcttttcat tacactttct agaacaactt tctgattttg ttcctgacca
    50401 agtaaatcaa cacccttttt cacagcgaca cctatagtag caccatttgt caaatcagat
    50461 atcttccctt ttatcgaacc aagtattcca cttgccatat cctttacagc tattgcacca
    50521 ctccatacct tacctgcaaa taatctcaat ttgggaaata ctttacttat aatgccactt
    50581 gccatatctt ttatagctat tacaccactc caaaaagtat ttttaaacaa cattaactta
    50641 ggcaaaattc tacccatagc actactcacc atatctttaa gattaatact tccttgataa
    50701 ggacgtttct ctacttgttt taattttccc aagatactac ttatcactct cttagtcata
    50761 tcttttgctt ttattacgat attccaaatc ttgccaccaa tcttttttaa atttccaagt
    50821 aatttatttt tagttttttc tacttcatca cttttagctt taaatattaa tataatcata
    50881 atatttgaat taaactcatt tttcttttga atcaacttat taaaataatc aataatcata
    50941 gctatagtta ttgctagtct cataatactt ccatttaaac ttccaataac tcctgaaaca
    51001 gcatttatgc tagaacttaa ttttgtcata gttgaactta cactactagc agtagtttga
    51061 acttttctta acgaggaatt taaactgttt actctattac ttgcacttcc aatagaattt
    51121 tttatgctac tagccattac attagtggaa agtgaaacag ccacagttgc tctcctaaaa
    51181 ttatcagtta ctgatataat ttgattcatt tttggtgtgt aattatctgt aaggtacata
    51241 tttatacctt cttctctcac atttcccatt acataccacc tcctgtcaaa ggacacactc
    51301 catatccatg tttcattttt tcaacttctt cctcaatttc taaggcgaaa aaagcttcaa
    51361 taagctttaa ttcgccttta tccattgcat aaaaaaggga cggtcttata ccttttttct
    51421 tccaataata gtacattatt gtagtcctgg tatccgtccc tattagtttt ttacctcttc
    51481 tatcactgca tttttaccat aacccataac atcttgaagt attctatata agttggtaat
    51541 ttcacctggt aataataatt ttcttgctaa ttcttttggt gttggagcct taaatttatc
    51601 cattagctcc ttatttttaa ataaaagctt tccatccaaa tcacaaacac cttctataat
    51661 tgtaagcatc tgcatctccg gtaagtctat atccgttttc atattttcat caattttaag
    51721 acaagtattt tgtatttctt catctttact tattgttaaa gctctacaca ttactttaaa
    51781 ttcctgccca aatatagttg ataatctctt aagttcaact atagtacttg gtctttctaa
    51841 gttttctgta tctgaattta aaagtaaatc tactatgttt atattttttg ataatccatt
    51901 ttcactcatt attatttgct cctttatcaa tcaaattcaa tcaactaact tttttactta
    51961 ttaactatct gaatttatta agtatatact tactaaatat cagtataaaa ctaaatataa
    52021 aactaaatta tatcaagaaa atcatactca gtaaatgtga aaggagcttc tatctctcct
    52081 tttactccaa cctcccaatc agctaaagtt aaatcatcaa atgctatatt ttttactgct
    52141 attctttctg ctccataaga atctgggtca tttaattttg atatagcaac aaatctaggt
    52201 tcagaacctc tctttatctt ttctccaatt aacttgtgca ttcttgaact aacgtggtat
    52261 agagttattg agccttttcc tttatatccc atatactttg tatcagtacc catttgacct
    52321 gctattataa tatcttcttt tgtaaattcc atctttgctt gaaatttctt tacttctgct
    52381 actttgtttc catcaagcca aagttctccc caagtaccac tcattacatt tctagcttcc
    52441 atatttgcca tattaataat cctcctatat ttctattgat aaatctatat cttccatagc
    52501 atcaagtact tttatttttg cttttaaaaa tactttagaa cctgtgttag cttcttttat
    52561 ttcttgtaat gtcatataag ataaatctac tccttttgat tttaaatacg atttttgtgc
    52621 ttcaaaatct atttcaacag tagaatcaga ttctataagt gctgattttt ctaattcttc
    52681 taaataactt tttatagcta ctatcaataa acatttgttg tcataactgt tagtaacctt
    52741 tcctatatag tcatctatta tcacctttct tatgtcacta tgtataatat ctaaagtgtc
    52801 aactattttt attttctgga acatttctcc tttttctgct gttaattcag ttaaagaatt
    52861 tactcctcta gcaattctta tagctcctgc ttctttaata agtataagct ctcctttatt
    52921 aacccttgat tctgcatcaa ctttcgtcat cttaggtata tcgactacat cactaagttt
    52981 agtataagtt actgattgac ttaaaggtgt acctgctata agtccagcca ccctgcttgt
    53041 aaactcatca acactgtatt tcttttctcc aactaacaca tcttctgtag taaaattaat
    53101 tatcccttca tgatttccta caacttttcc taatacagct ttaaccttaa ccttatctat
    53161 atctctaagt ttaattatcc aattttttat agcagtctta tcagcttcta ctgcttttgg
    53221 catacataga taattaaatt ccttagtctc taaaaaatct aatgcagttt gaatatctgc
    53281 ttctccttct attacataaa ctaataattt atttggagtg ttaacatttc ccatcaaagc
    53341 taaatttata tattctttat tttcagcaga taaatcaact ggtatatcct ctttttcatg
    53401 tatttcatta agacctagtg ccttagcatc tttaagtacc attgcaatta ttcctctagc
    53461 tgaacgttct ttaacagttg tagctagctc cttaaatgat atgttgatac ttggtaatcc
    53521 tatagccata ctatcactct cctaaattta aattgatttc tttcatattt tcatatacta
    53581 catcttcttc atatacacta tccagatagt ttagtgtaaa tgtaaagttc aatacataaa
    53641 ttgactcttc ttttttaata ctttgttcta gctttgttat atttaatttt ctgtctgtta
    53701 cctttatatt tctgttaaat agcttattta attcatctga aatttcatac attctaatac
    53761 tctttgactg tggttttggt aagtatttta tagagataac aatatctttg ttattcgtat
    53821 ttaacattac aggtgtacaa ataactgata gtatacttac aaaaaaacaa gacccttcag
    53881 agccttgcac actttcatca tcaataaaaa tactttcagt aaagtttttt ttgagaatct
    53941 caataattgt ttctaatatt tccttgtatt taagcaaata atcaccacac tatcactaaa
    54001 tattcttgct taatctgata atcttactat aaatgatata agtcattttt aaatatatat
    54061 ctcatttatt cctgtcaagt atcttctata tttttaggta atattattct tttcaatcta
    54121 tcacctcctt caatatggat ttctttcaca ataacattat ctcacatatt ttattgccta
    54181 ttgttgcaat ggtgtatata aagtgttgta aaattgtcct attttttata atatctcact
    54241 caatttaaat atcatctttt tctttaaatt gtagcaagat gttctatcta agtgtagttt
    54301 catagaaata tatgtcatat tgttttttgt cttactatta taaaaaagat taaaaaattc
    54361 catttctata tcatttagac acgttagagc attttctatc ttctcttttt ctatttctat
    54421 atcttctttt tccattttta attttcttaa tctttcctct ctttttaaca cctcattttc
    54481 cacagaagag cttatgttat atgtgttact agtcttttct gtatatacca ttgctccaca
    54541 tccagagtat tcattctcac atctttttat gtccaagtta atattcttta tctttatatc
    54601 caaatactta taattatgta atcttttatc tgtttcttta aataatatat cttttttgtt
    54661 ttccatagta cttccccttt tttatatact tattattagc ttcaaattta caataatctc
    54721 tttagtgcac agttttttac taatctcaca actttcaaga acatattgtt ctataactgt
    54781 ataaaaaaaa cttcttctat attttgttct aaaatactag aaatcttctt agccataaga
    54841 agtccaggat tttttatacc tctttctatt tgagatatat aatcatttgt aattccagcc
    54901 tttctggcaa gttgaatttg tgtcatacct ttgcattttc tataatattt caagttattt
    54961 ttaaacattg ttttatacct ccattactat taagaatatt ttgttcttcc tcacttagat
    55021 tatatagaat tatttgttct ttatcaatag attttagaaa aaaatattct tttatatttt
    55081 attagtttta ttttttagaa caatttgtta taatctatac ataaggtggt gttataatgt
    55141 ttgccaaaag attaagagaa cttagaaagg aatttggatt gactcaaaga gaacttggag
    55201 aaaaagtagg cgtttcccaa agagtcttag ggtactatga aacagaaaac agatttcctg
    55261 atgaacacat tttaaataaa ttggctgatg tatttaatgt atcagttgat taccttcttg
    55321 gaagaacctt agttaaggaa aatattgata cagtagctgc acatagaaaa aatccacatg
    55381 aagagttacc tgaagaagca caagaacaac ttaatgatta tatagaattt ttactaaata
    55441 aatataaaaa aaaataaacc atatgatgag cagtctattt ttctgctctt ttaatataat
    55501 ttaaaggcaa acatacattc tattttaggg ggatttttat gaataatttg gataagcttt
    55561 ttgaattagc ttctcaagaa gagataataa ttcattatac cacttatatt gcaggtgatt
    55621 tagaaggact atatataaac aaacatggta ttaaaattat atcattactc agtaatttaa
    55681 aacaaaactc aaaaaaattg acatccatct tagctgaaga acttggacat catttcacta
    55741 gccttggata ctatgtatcc tcttataacg attattatac aaaaattatt atagataagt
    55801 gcgaaaataa agccttaaaa tgggcttgtg agttcttaat tactgaagaa gatataataa
    55861 acataattaa ctctggcatc acttgcgttt atgaaatggc agacatactt aatgtggata
    55921 ttactttctt tcaaaaaaga ttagaatttc tatcattaaa aaaacagtct ttacaacttg
    55981 gaaataataa atatttaata ttaactaatt tgccgtattt ctacatattt gatccaattt
    56041 cataataaaa atagtagtaa ttttaactgg cttaacagta aaatctatat atttatttta
    56101 acaaattttg gtttctataa attcaatatt aatatataat aatgatatca tattatttaa
    56161 aattctaaaa acaaatatat gcttttgtta agaaaggttg tttgatgaat gtataaagaa
    56221 aagttgtttg ataattattt taagttctta gcactattat tttggccaat tatgtggtat
    56281 aagtggatag taatttcaaa tggtactctt gaaaatatgt tatttaccat atatgcaatc
    56341 gtcgcaattg ttttcatcat tttatattcg gtgtttatga taaaatataa agacattaca
    56401 caaatagatt tcttttacag gataagtact ctacttgctt ttatatttac actttttagc
    56461 tttttaatat acccaaagag tttatttttc ttgtatttaa agattatttt tactggaata
    56521 tacctttatt attcaatagt aaaaactctt aaatttaaag atgacgaagg tgtagtgggt
    56581 attatgagct cacttttatt aattgtaata actttgttct actaaattta attctatttg
    56641 acttaatatg gctttaaata ttagacatct acattatttt ctgatattat ttaagatggt
    56701 agtcttatat taataatgaa atacactatg aaggagttaa ctattatgga aaaaaaagtt
    56761 ttagcaacag ttggagaaaa agagataact aatattgata ttgaaaatgc attaaaatca
    56821 ttagaccctt atcaagctat gcaatttaaa actgaagaag gaaaaaaaca cttattaaat
    56881 gatttagtga atcaagaatt attcttctta gatgctaaag aagaaaaatt agatgaagaa
    56941 gaaatattta aattagaaat gaaaaagata gaagaaaatg tattaaagca atttgctata
    57001 aataaagttt tatctagtgt taatgtaaca gaagatgaaa aagtaaaatt ctttgaagct
    57061 aataagagct ctttctctaa accagaaagt gcaactgcta aacatatatt agtagatagt
    57121 gatgaaaaag ctaaagaaat acttgctcaa ataaaatcag aagaaatatc ttttgaagat
    57181 gcagctctta aacattcttc ttgcccatct aaagatatgg gtggtgattt aggaacattc
    57241 ggtagaggac aaatggttcc tgaatttgaa gaagctgtgt tctctatggc taaaggtgaa
    57301 gtaagtgaac cagttaaaac tcaatttgga taccatataa taaaattaga agaccttcaa
    57361 gaaagtacag agtctacatt tgatgaagtt aaggctgaag ttgaaaaaag tttattatat
    57421 caaaaacaaa atgaagttta tggaaataag ataaatgctc ttaatgctaa gtacggaaac
    57481 cttgtaaaat acaacgatta atcataaggt catatataaa aaagctgtct tttcacaata
    57541 tttattagaa aagacagctt tttatattaa agtttaaata ttcagtttca tattatcatt
    57601 cttttattgt aaagaactca gcttaaaagt ttaaataaga tttttaatta tcattagcta
    57661 aatttttata tccacgtatt atctcataac agtaacctat tacatctctt ctttttatta
    57721 tcccaataaa tgtgtcttgg tcatctataa caggaatgaa attttgattt aaagatttta
    57781 taactaaatc ttcaatatct gcgttgatgg aaacaggaga attatccatt tttctattta
    57841 tatctgtcac tggaacatct tccaatccct ttaagtccag atttaaatca ttttttaatg
    57901 tccataaaaa atcaccttct gttatagttc caacatattt accatcctta cttattattg
    57961 gaattgcaga gtatttgtga tattccattt tttctagggc ttgccttata gtgtagtctt
    58021 catatatata tgctacttca ctttttggtg ttagaaagaa taatatgttc attacactac
    58081 ccaccgttac tgaaaactta taaatattac tcaatattta taatgttact tttttgcagt
    58141 aactttctcc tttcttattt tctaagtatt cttaatacta tacgctgtaa caagcgtttt
    58201 tcctttgctc attttaatct tattatgctt tattaatatt tttatatggt ctatcagtat
    58261 cacttattct ctttttagaa aatttactaa aaattaattg acttaaactt agccataata
    58321 attttactct acactattaa ttttaacata tttatctcat tattaatgat tttattttaa
    58381 taattttaat ttattttgct attaatttta tttacaaaaa ctgaaaaaac cgctaaatga
    58441 ttagcggctt atctctcata ttactagaac actaatatat atgaattttt aattataatc
    58501 taactacgtt agcagcttga ggacctttag ctccatctac tacttcgaac tcaacgcttt
    58561 gtccttcttc taatgttttg tatccatctc cagttatagc tgagaaatgt acgaaaacat
    58621 ctccttcacc ttctacagat atgaatccaa atcctttttc gttgttaaac catttaacta
    58681 caccagtttt cattaataaa tcctcctaaa aaaacacaaa tatttagcta ctcttttctg
    58741 taaccttatt actactctat catatatagc tatgtttgtc aattattatt atttttatac
    58801 attaataatc aattttttta ctttataatt ttaaatgatt attatctttt acactttatt
    58861 tttctttata attttttaat aatttatttt tattatatgg aatcttatgg acttatcact
    58921 ccaacctaaa tcccatggca ccaacattct atcagtatta tgacaagtta ccaaaggata
    58981 ccctcttgag tctaatcctg tcactgtcga aacatgtgtt attctgcctt tcttctcata
    59041 accaacaaaa tcccctggac gtaaattata agcttctttg tatacttctt cataggaacc
    59101 tttagcaatt aatgaacctc ttccactata cagtgcataa tttttaaaag cttgtgcatt
    59161 tacccatgct tttgtacctg ctctctcgct ataattccaa attgagttct ttttgaacct
    59221 tccactttca aacattatct gtgatgcaaa gtttgcacaa tctccacctt ctggattata
    59281 atccctatag tttggattaa atttcatacc atgttcttca tcagctgcgg ctccacagta
    59341 tttatgtgca taatctatag cctttttttg ttcatctgta agctgtaact ctacaccatc
    59401 ttgttgacca atataatttc ttatatcatc agattttata ttttctaaat ttaaagagtc
    59461 tgcaaaaggg tctgtatacc actctttagt tatgacatat tgattatcta taatttttac
    59521 atttagataa tgatatgtac ctattctaaa ggcattttct ttgtcctttt gattttcata
    59581 tgaatactta tattcagtcg atactgaaca gattatacca tagaggtctt tttctttttc
    59641 ttttattttt ttaatcttaa cccttgtctt tatgtcttta aattttacac cttgcttact
    59701 agaccaattt tctaaatact tcatcttttt tacttcattt tcataagccc acagaccaaa
    59761 ttttttatcc gtctcataaa gaccttttaa aatgttttca tttttctcta atattgcctt
    59821 atttctgtaa tcaaataagt tttcaagcaa tagtttatat tggtctttta catcatcacc
    59881 ttcaacattt gcagattcca tgactttttc ttccatattt ttcatactta aatcattgat
    59941 taaaaataca cctgctgtag tagctaaaga caaaaataca aatgccatta tacctttgat
    60001 gtacttattc ttatttttca gtattttcaa agctacacct cccaaatagt acaccttaca
    60061 aatcaaatta caaagaatat tctgtcacat atagtaattt tcatatttaa taattctcta
    60121 ttttattatg tccaatatta aaaattaatt gtatcaatac actgtttttt ttacaatttt
    60181 ttattttata atctactttt ttcttttttt tatagtaata tatatgtata taaatatttt
    60241 ggtatcatta taattaatac atactaatgg agggtttttt atgcaaaaaa aagtcgcagc
    60301 aattaatgac ttatctggaa taggaaaatg ctcattatcg gttgctatac ctatactttc
    60361 agcattaaag gttcaatgtt gtccatttcc aacggccata ctttcaagtc aaactggtta
    60421 tcctgaattt acttttttag actttaccga tgaaatggta aaatattcaa atgtttggaa
    60481 aaatttaaaa gtcaattttg atagtatata tagtggtttt ttgggttcaa agcatcaaat
    60541 tgagatagtg gctaatttta taaacgatta tcccaatgct tttatcgtag ttgaccctgt
    60601 gatgggtgat aatggagtta tgtatccaat attcacagaa gaaatgagac atgaaattaa
    60661 agaattagtt aaacattcag atttaactac tcctaattta acagaagctt gtttcttaac
    60721 tggaaatgat tataccaaaa gcgattataa tagagatgag cttatatata ttgcaaaatc
    60781 tgtatctgat ttgggaccta gcaaagtcgt tattactggt atattagaag atgataatat
    60841 attaaatttg gcttacgata gagataatga ccatgtattc tttacatcag tcaaatataa
    60901 taattgttct tatagtggaa ctggagatat attcacatct atactttgtg gtatgttagt
    60961 aaataaacat gatttgggag tagcggttaa tactgcaaca gattttatat ataaaactat
    61021 aaattacaca tctcaatttg atactgatag aaatgatgga gttatgtttg aaaacttttt
    61081 atcagattta actaatatat aaagtcaaaa aaactatcca ttttataaat acctataaat
    61141 cataaaattt aggtatttac aaaatggata ttatttacta aactattggt atttcaattg
    61201 ttaccatagc accaccagtt ttcacagaat tttcaatata taaaatccca ttatgttttt
    61261 gtacaatatt atttacaata tagagtccca ttccataatg agatttagaa tttctactca
    61321 aatctcctgt ataaaactgt tctgtagctt ttgacaaatc tgctttagaa aaaccacttc
    61381 cacaatctgt aactacaaat tttaagtatt tattacgtac tgatacactt atgtatagtt
    61441 tactctggct tggtgaataa tctatagcat ttgaaattat attcataata gctctgaata
    61501 acagttctct atctatagtt atatttttag gcaaattatc ttgtttataa aactccacat
    61561 ctaagttttt agtactagct aatgcttcta tttgcactaa gacatctttt ataaactcac
    61621 tcatactgat tgcttcttta tttaatatat agccattctc tgtttttgat atatctatta
    61681 aagtattaat atatttttct atttgagtga caccctttga gatatattcc atgtattcta
    61741 ataactcagg attttcattt atttcaatta ataagtcagt atttccatgt ataattgtta
    61801 gtggtgtttt tatatcatgt gccagtgcag atatctgttc ctttctattt tcttctagca
    61861 tccattgttt ttctaaagaa tcttttaacg ccaacttcat tttatccata gaaaaaagga
    61921 cattattaat ttcataaatt ttactagatt ctacaacaaa atctaaatcc tgttgttcta
    61981 ttttttctgt agtatttttt aaaagctcca tttcaatatt aaatttcttg ccaaatactt
    62041 ttgataatat aacaatttca ataaaaaata ttatactaaa aataatcata cccaatgtct
    62101 ctggttttgg taaatatgct cttaaaattg gagaactata ctctgatact attttgtatt
    62161 ttattataaa aacttcatct ttcttaaaaa actttatata actttctgaa tatgcatgcc
    62221 tttcttcaat atctctcatt aaattccata cttcttttga ttctttttta ttaaaggtcc
    62281 ctgaaattaa actcccatcc aaagtataaa ccccatactc atatatactt ggaattatat
    62341 cttcagttac tttttcactt gaaataatct gttctttata tttattaaat tgtttttctg
    62401 cataattagc tggtaaaatt acacctgatg ataataatac agaaaatgat aacattaaaa
    62461 ggagtacaat tgaaattgtc ataataaaga ataaagataa atattttata aaaatagttc
    62521 ttaacttttc aacttttttg ttgttagatt ttttacctcc aagcatttgt accctgtcct
    62581 ccaatagttt aattaattca taattaatat ctaaccagtt ttttatttga ttattttata
    62641 tctttttatt gctaagttat attttaacat aataatataa ataaacagtc aatttttact
    62701 ctattcttct gattttttac cttcccattt agaaaaccaa atacataaaa ttacaaatgc
    62761 taaaattgtt acaaaaccac acattaaacc tgttgattga tatgctttta ttgattcaac
    62821 ctttatatat tcaaccgttt tagaactcga aaaagacgac caaatagtta taaatctaac
    62881 accccatgca caaggaaaat actgccaaat accagaaccc aatccagtta ataataatgc
    62941 tgaaagtaac atttcaacta tacctactcc aattgatgtt ccttttccga accttaaact
    63001 taagaataaa tgtaatatgt attcaaataa attacaccca attaaaatta gaattgaaat
    63061 catataaaag cttgatgcaa agtaagcctt agatatacca aatttaaaac ctaatacaga
    63121 cactaatgtt gctacaaaac caagacatac taagattata tatttactta taagagtaag
    63181 atattttgga ttagatgttg ttaacatatg tttataattc cctgcataat attcttgttc
    63241 aacaaacatt gaacacacaa cacctgacaa taaaggaaaa gctattgcta taacttgtaa
    63301 atatgctact atctttagta tattatcagc tcctgaaacc ttataatacc ataaaaacaa
    63361 tcccatcccc attaaagcaa tgcaaatgtg cattagtatt ataaaatttc tctttaattt
    63421 tattaaatca gaacaaaata ttcttattaa ctgtctcata ttacttcacc tctctattat
    63481 tgaaccaaac ccttgtagct aaagcaaata atacaaataa aacaatagat attaatactc
    63541 ctggcaaaat aacagcatta tttaaaaatt cacttccctc tggtacagga agaccatttg
    63601 gcagaatatg caatacaaca gccattaatc ttgaaggaat cgaatatgga aacatatacc
    63661 acatttctgt agttgagaaa acagcaactc caacaatagt aaagaacata tttattagaa
    63721 ctgtaacaaa tataccaaat tttgaagcta aaaacataca aagaggaatc tgccacataa
    63781 atagtaaaat aattaatata gttgcaatga tattttgacc tattgaaata gtttctttat
    63841 agattatccc aacaaaaact acacctattg cagaaataat tgatgctata aaacaacaaa
    63901 taatacagta aatcattttt ccagtccaaa cgtctttcat ttcaattggc aatggtaaaa
    63961 taccacgata tttacttttt tcatctttta atactattaa agaagatatt aatgttaatg
    64021 ctcctggaag aaatgtcgta taccaccagt tgaaagcagc attttgccct ccacctagtc
    64081 cacataaaag tatacaaaac actggaacta tccatatcaa cttcattcca aaagttcctt
    64141 tcatcttttg aaattccact ctaataaatc tttccatatt actgccctct ctttctattt
    64201 tcagctacaa ctttcataaa aagtttttct aagttttgtt cttttgatac ttctccttga
    64261 taacccatta ctccattaga aattattcct atttcatcta caacttgttc aacttcagac
    64321 aagatatggc ttgataaaat aactgtaatt ccttgttttg gaaaagaacg aatcaattct
    64381 ctaagttctt caataccaat agggtcaaga ccatttgtag gctcatctaa gattaaaagt
    64441 tttgggtgat ttaataatgc aatagcaata ccaaggcgtt gcttcatgcc tagagagaat
    64501 tgacctgaac gctttttaaa ggtatctctt aaatctacag tctctaaaac ttcttcaatg
    64561 cgagagtcag gaagaccaag taaagtagta tggactttta aattttctcg tgctgttaaa
    64621 ttctcatata tagcaggaga ctcaataaga gaaccaatat ttgataaatc ctttctagtc
    64681 catctatgtc cctcaaacat tatttttcct gaagttggat ttaaaatccc agttatcatt
    64741 tttaataaag tagatttccc agctccattt ggtcctaata atccatatat agaattagat
    64801 ttaattgcta gtgaaatgtt atcaactgcc atctgctcct taaatttttt agaaactcct
    64861 tttacctgca aaatataatt actcataatt ttcatccttt cttttgtcaa acttatttac
    64921 aagaatcatt ctaaatcata aatataagga ttttataaga attaaaaaac aaaaaaagat
    64981 gtgttaaaaa cacatctttt tttatcttaa ttctattaat tttccattgt agtatatctc
    65041 tacttcttca atccaaatgc tattatcttc ttcttggatg acatttttaa taatattatt
    65101 tatagtatat attatatttt gttcattcaa ataatcatct ttccaagaaa ctctactttt
    65161 tttatctggt tctatcaagt ttattttaac aagattatct ttttccttaa cttctacttc
    65221 catgtctaaa ccattaaaat actcatttga taatgtatct aagattaatc gcagtttatc
    65281 cttaagtgaa ctttcttcat caatctgtaa gtactttact attttctcat cctttgaaat
    65341 tatctctata ggtattttag tagttttttt agaattaatc attttactag ttgtttcttc
    65401 ttttgcatct tcatccttct ttacaactgc tgattcttta gaatcaacta gctcaactgc
    65461 actgatgcta taatccatac atgccgtact caataaagta gtagcaatta ttaaaaaact
    65521 tactgctatt ttattcataa gtatccctct cctaattctc tttcgatact tattatacca
    65581 tagtatagat tatattttta tacttttaaa tcaatttata aattattata gtaaattatt
    65641 tacaattcta agctatttga atttattttt atagtatatt ctttctctaa attcgacaga
    65701 tttttattca aaagcccttt tatttctctc gtatttctat acttgttgct atgttcttca
    65761 ctatgttcat aatcatatga atcattgtca tattcttcat cattattaaa ttcttcaatt
    65821 gcttcttttg actttatatc acaattaaat ttatacttat ttactggtat atcaagtctt
    65881 accttagaat ttggaacttc tatgtccagg aacttagcaa ttggcatatc agagtacaag
    65941 taaaattcac tttcataatt tgaatttcta cctattttct cttttatatt tacattttca
    66001 ggtatatact cttctatatt attgataaat acatcttcat tctctgaaga tatatacaat
    66061 gactctgatt ctatgtttac atttttaacg cctaaaattg attttgttga caagtgaaga
    66121 ttgttattag atattaagtt taggttttct aatctattta ctttgttctc tgttatagct
    66181 ctactaaaac ctccataaga agttttatat gttatagtat ttgaagctac attatcgtat
    66241 acaaataagt gtgagcttat acttgatgca tttatgtcta cattatttgg tacatatatt
    66301 ataatttctc tataatcatg tgaaaacata ctatttatag atgtatttaa taattggtcg
    66361 aaatttttaa tctttttaat tttattttca tattttcttt caccttttac aactaaagtc
    66421 ttatctttta aagttacatt gtatttgtaa aactcattat ttcctcttgt tgttacacgc
    66481 acatcttcac ttgaactttt ctttattgta acgtttatat tgtcaacagc tatatctaac
    66541 ttgtcaatat ttactttttc ttgataaagt ttattttctt ttttaaattc agcttccttt
    66601 tctaaaccaa agtttattag gcttggcata actaaaatcc ctgaccatgt tgtccctatt
    66661 atacctatta ccaataaaac cgcagcaaat atagcaagtt ttttattcat gtttatcttc
    66721 tcctttctta ttttctatat cttcaaggtc cttatatatc gcctcaaaat ttatactatc
    66781 atcattatat tcatcagttt cttttatgct ttcttcttct ctattgtagt aatcattatt
    66841 atatgaatct tcattaatgt ctttattcaa atcttcatca tttaaagtag ctttttttct
    66901 tttttccatc ttttcatttg cttttatata aatatttttt ctctttatcc aatgtatata
    66961 attatttagt aattgtttac ctagttttat ggcaaataat aaaatttgcc atgcaagtat
    67021 ctcaagccct acaaatgcta tggttgcgaa aatacaaaac atcataacat ctggaaccat
    67081 tgctataaat ttaatcacaa atggaattaa tataacaaaa gcaattaatg agcatactaa
    67141 tgcaatagta gcagatacaa tagcacatac aaacgcaaat gctggaacaa ttagaaataa
    67201 agataacact actaataacc cctttataac ttgtctggat aatcctccta caccttcttc
    67261 tatacttggt gtaagtttat catttatatt ttcttttgat ttattgtact tttccttagc
    67321 ttcatctttc aagatagaat aatccttttt tacatttgat ttaaatctac taaatttacc
    67381 atttaatatg tctgtattca ttatttttcc atctatattt tcttttgatt tactatactt
    67441 ttcttttgct tcatctttta agatagagta accttttttc atatctgatt taaatttact
    67501 aaacttatca ttcaaaacat ctgtatttat tattttttcc tcttcaatat ttttttcttt
    67561 agtttgtaag ataagttctt ttgctataga ttttggtgag ccaagtgatg ctattatctc
    67621 catatcactc tttccctcta taagaccatc tacaaaatac tcttcataat ctctcaatat
    67681 atcattaact tcgctctcag aaaaatcttt ttttagataa tcctttaaaa tttcaagaaa
    67741 ctcagtttta ttcaagttca ttacctccct catcttcact tattaaaatc tcaacagcct
    67801 ttacaaattc tctccactct tccatcagat tggataaatt ctcttttcct agtgaagtta
    67861 ttctatagta ttttctagca ggaccttcat tagattctag tatatatgtt tcgaaataca
    67921 aatcttttgt aagtcttctt agaataggat atattgttcc ttcatttaca tctattactt
    67981 tagagatgtt atgtactatc tcatatccat acatatcttt cttagatatg agagcaagta
    68041 cacaaatttc taaaacaccc tttctaaatt gtgtgttcat atactccatc ctttctttaa
    68101 atacacagta ttgtgtttta caaggtacta tgttaaaact tcttatatcc tcataataac
    68161 acagtactat gttctgcaca atagttattt ttaaatattc ttgttgatta aatccttcta
    68221 taaatgtata atactctaat cagatatatt ttatgaaagt ggtgataaat tggctaaaat
    68281 gaaagatgat aaaacaatat taatcctaac tgctcaattt ggtgctggac atataagtgc
    68341 tgcaaaagca gtcaaagaat gtattattga aaaatatagt aactataatg ttgttataca
    68401 aaactttata aatgcaagta ttcccatgat gaataagcct atggtaaaac tttatgaaaa
    68461 caatacaaaa tatactcctg gattatataa ttactattat tactttaaga aatcgtttga
    68521 ttcaagacat gatttatctc ataaattata tacacctaaa ctttctgagt atattgctga
    68581 tataaatcca gatttgatta tctctacatt tccactagct gctgcttgtg taaataactt
    68641 taagataaaa aatcctgata taaatatacc tacacttaca gttataacag atgttgtaga
    68701 tagtatggaa tgggtttttg aaaatacaga tttgtatttt gttccttctc ctgaaataaa
    68761 aaatagattt tttcagaaag gaataaatcc tgactccata aaggttactg gagttcctgt
    68821 tgataagaga tttcaaattg aaagtaaaga actatgttgt gataaatata gactattact
    68881 tctaggtgga ggaagaggtc tatttgatat agatgaggat tttatgcatt ggatagatga
    68941 atttattgaa gaacatagta attctataga aattacaata gttactggta aaaacaaaaa
    69001 attatatgac aatctaactc ataaaaaacc tctaaaaaat attaaagtac ttggatttgt
    69061 aaacgacatg tataatctaa taagagaatg tgacctaatg ctaactaagc ctggaggagc
    69121 aactatattt gaagctattc aatcacaaac tccagtactc gtaaaaatgc caaaagttgg
    69181 acaagaaatt gaaaacgcta aatttataat agataagggt cttggcatga tttatagtga
    69241 tgacctagac cttaaaaaca tattttataa attagtatca aatgaatttg attctataat
    69301 aaactttatg aaaaaaaatt taaaagaatt taaaacagtc attcatccag agaaaattgc
    69361 tgattatata tcagaattaa tagataatca ttacagttaa attgtactat taaaaaattt
    69421 caaacataaa attaaaggca atcaagtatg attttacact tgagaattta ctcatagtgt
    69481 ttaataatac ttgattgcct ttatcatatc aaaatcaaat tgttatatta gtatatattt
    69541 ttcttgtact gcatatacag ttgttgtatt tcttccatac ttctctttaa ttctatttgt
    69601 aaatctgaag cagtctggta atccttattt tctatagctt ctctcactct agtgaatagt
    69661 gattctctag ttaaagtatc cttcataata ttgaacttta aatccgatat tgagttccaa
    69721 actacctcat caagcgcatc catattttct tttgtgtgta tcttgacaat acttcttatt
    69781 ttttgaatcc cagcctctat tattctagtt tttaatttct tttgccactt atctatagct
    69841 ccaatcttaa atgattctat tatactatca gtaaatacat caccttgttt taaagatttt
    69901 aattttgaag catatatttc taagtttttc atattttcat aaactgtagc tggtggtatt
    69961 ccaaatcttg catttctttc ttccaaacta taatgttcaa atacatcatt ttcatctcta
    70021 tatgctctat ctttttctaa atagaaactt tcttcaccta catttttaga taactctttt
    70081 tcaagttctt ttgtactaag accactctta gctgctgctt ttataccatc caacattgtt
    70141 tgataacatc ctgctattac taaatacgtg ttagatagag ggcttggtga ccttaattca
    70201 aatcttacag tctttggatt tttcatatct cttattaatc caacaagcac tgacctattt
    70261 cttgatggaa tctcataact atgccctaaa gatgtaacta tacatacagg agcttcaaat
    70321 ccaggaacta atctattaaa tccatcatta gaagctgtta caattgggtt taatacttca
    70381 taattgtaaa gaagtcccat aagagcccca tatcctagtt cacttagata atcttctttt
    70441 aaatcttttg gagcaaatag attttttata cttccatcct ttaacttcgc acttactcct
    70501 acatgtgtat gtccaccact tcctgctact ccatgaattg gttttgcttt aaatgtaact
    70561 tctagtccat gtgatgtaaa tacatcctct ataacatctc ttactaataa ttcattgtct
    70621 gctgcttgta atggtgtaga aaacttccaa gaaacctcta attgctccat agcatggttt
    70681 gttcttccat ctatactaat agaactttgt attcctccga cctctttgtg agccatttca
    70741 gggtttacac ctagcttttg aagtataatt aaacttttct ctaaacaagt tcttataata
    70801 ccatgagttc ttttccagta ttgctctttt aggctttgtg atacatataa tttctctaag
    70861 tcagctttat cctcaggagt attaacccag aactcaagtt ctgtagctgc tgttaacatt
    70921 atttcctcta tatcatctac tgaatctatt cctatgttat ttattacatg tggatattct
    70981 ctaaatattt catacattga ctttttaaag tacttatctg ctttttgaag tactcctcta
    71041 gaacatactt ttttattatc atgtattaaa aatgcaggta tctttaatgt tccaacaggt
    71101 agacctactt cttcgtctat atattccata ttgtaatcta cataccaatg acaactttta
    71161 tctggcatta aatctacttt cgcattattt aatgtagcta tattataaag ctcaacactt
    71221 gaaccatcag tctgtatagc tgattccaaa aatttatcta tatcctccaa aaataattct
    71281 acaggaatct tttcatctgt tgcatttcct cctaaatcaa cccccattaa ggaaacaaat
    71341 cttatatttt tattgctttt taggatttct cttaattctt cattagtgtg tttatctttc
    71401 tctattacgt ataatagact atccattttt ccactctccc ataattttta tgtatatttt
    71461 attttgttaa atacaagata aatttcattt tccttacatt tatgaatttt tcttgcaaat
    71521 tattcgtgtt ttattcgtgt ttttatttat attattatat atcaagtata aaaagttcgc
    71581 aatatttttt attggaaaaa atattataca tacaatagtt taacattttt acaaatatgg
    71641 ggtatactaa aataaaagta tttttatttg aaaatttaat tttatttata atataatcta
    71701 tagtaaaaga aataataaaa aaatttagga gataaacttt atggaataca taattttcga
    71761 tttggaattt aaccaaggat ttgataaaaa actcaataaa actgtatcca atgaaaagtg
    71821 tccttttgaa attatacaaa taggagcaat taaattggat tctaaattca atataataga
    71881 tacgtttaat agttatgtaa aacctacaat ttataaagac atacatccct ttattagtcg
    71941 tatgactaat attaaaaatt ctgattttaa tgattcgcct actttccctg aggtctacaa
    72001 caattttata aaatttatat catcacaaga ccctatatta tgtgtttggg gagctggaga
    72061 tttaaaggaa ttatacagga atatcaacta tcacaagcta ccatcaaatt ccttacctaa
    72121 atcttatatt aatatacaac aacatgcatc taaatatttc aataatccag caggaaaaag
    72181 cattggccta caaaatgcta tttctatatt agaacttgat gaaaaaatgt cttatcacaa
    72241 tgctttaaat gatgcatatt atactgctaa agtttttatt aagatataca atccaagtat
    72301 agtcccagat atatatcttt atacaagtat aaaacctaaa actataagat attctaacaa
    72361 aaaaagagtt gattatgata agttatttga tgaatttagg aaaattttaa atcgtgaatt
    72421 aactaaagac gagaaaaaaa tcattaactt agcttataat atggggaaaa caaatcaatt
    72481 tacattagaa aatgttaagc aaagaaaaaa caaatagagt ttatttagat aaaaaatagg
    72541 catgtagatt aaaaaactag ttaactttaa atttatatct acagcccaat ttttatcata
    72601 attaattttt attttatctc taattcaact ggacaatggt ctgaacctaa tatttcagtg
    72661 tgtatatccg cacttactaa tctatcttct aattttttgg atgcacaaaa ataatctatt
    72721 ctccaccctg cattattttt tcttgcatta aatctatatg accaccaact ataaacacct
    72781 tctttatcag gattaaaata tctatatgtg tctataaacc cactgtctaa taatttagaa
    72841 aacttctctc tttcttcttt agtaaaacct gcatttttca tattattttt aggatttttt
    72901 aaatctattt ctttatgtgc aacgttcata tctccacaca caattacagg cttatgatta
    72961 tctagtttgg ttaaataatc tataaagtcg tcttcccatc tagttctata ttctagtctc
    73021 tttaattcag attgagaatt tggcgtatat actgtaacaa agtaaaaatc ttcaaactct
    73081 agagttatca ctctaccctc tttgtcatgt tcttctatat ttattccata cattactttt
    73141 aaaggctctt tttttgtaaa tatagcagta cctgaataac cctttctctc agcataattc
    73201 caatattgaa aatatcctgg taaatctaac tctatttgcc cttcttgcaa tttagtttct
    73261 tgtaaacaaa atatatctgc atctacttct ttgaaaaagt ctaaaaatcc tttcccaaca
    73321 caagctctta ttccattaac attccatgat ataaatttca tacttatact cctcatctaa
    73381 acattgacac actccccata gctaaagatg ggggcttttc aacaatttta ttgtaaattc
    73441 ttaattcact tttattttaa caatgctata ctataatttc atctaaaatt actatttact
    73501 taatacctaa aaatatatgt tttaatcaat ttttaacttt tttgttaaat cttcagggct
    73561 cattgaagaa acatacatat ttgttccaag ttcaaatcct ccaaaattat attttcttgg
    73621 gattatgtgc atatgaacat taaaatacga ttttgtttca atctttgttg gatgagtgtg
    73681 aatacataaa ttaaatggca tatatccatt gatattatat aacttcttaa acaacttttc
    73741 aaatattgta gaaagctcct gtatattatt atcatttaac tcaccaaact ctattttatc
    73801 tttaaatatt attcttactt ctccactata cttggttgca tatggtataa gtaccaaaaa
    73861 agcttctcca ttataaacaa ctcttctatc taaacttatt tcattttcta ttaaatcatc
    73921 atacaaagag cttttattgc tgtcataata ctcctttgaa accaacagtt cattcgtaat
    73981 ttcaggtgga ataaaagaca tagacaatat ttgagcatgt ggatgcatca aagatgctcc
    74041 tgcctttctc aagaagtttt tgaagatact aacatactct actttatcat ctttcgacaa
    74101 atctctaaat ctatttctat acataaaaaa aacatcttca aattcttttt gactcatgtt
    74161 ataaaaacta cgattatgtt tatcgctctc tatcattact tcatgaacac catatacatc
    74221 tcttgccata tcatcaatta taggaaattt attgtagaca gattttacaa gccatccttc
    74281 ttcactttct atttcaaata atgcatcagt tgcatgagct tcatttcctt tgcaaaatgg
    74341 gcattcttca tcatattcat tagtttcttc atcttcattt gggatatctg ctgtatctaa
    74401 aggtcttttt aacctatctg tagcaaatat aacaacatca ttggtaattg gatctattct
    74461 taattctttc ataattaaca cctcttagtt aatagccttt aatataatta tatgatattt
    74521 atcgtatctg ttaaataaat ttataatatt ttttataatt ttgcatattt attattatat
    74581 attttgtcta tagctgaaag attataacta aaaaatcact atcagtatat cagaatatta
    74641 tcttactata aattaattta tgaatacata atttagtggc ataaacatgg gtattttact
    74701 ataatttgtt aaaagtttat tttaaagcta tattaatttt ttttgatgat ttttacccat
    74761 aagtatgtta ttattatctt gtaaagatgt cttgtattca aacatacaat ttacataata
    74821 caatatacgt atttaaatta aatagggggt attaaaatga attattcaaa cagagttagt
    74881 gcaatgcaag cctctccaat cagaaaactt gttccatttg cacaagcagc aaaagataaa
    74941 ggaatcaaag tatatcactt aaacatagga caaccagaca taaaaactcc taaaggattt
    75001 tttgatgctg ttaaaaactt tgatagcgaa gtcttagaat atgctacatc agaaggtatt
    75061 ccagaattat tagaagcact tcaaaattac tataaaactt acgatatgaa ttttgaaaaa
    75121 gatgaattat tagtaactaa tggtggtagt gaagctttac ttttcactat gatggcagtt
    75181 tgtgacccag gagataatct attagttcca gaaccattct atacaaacta caatggattt
    75241 ggtcaatctg taaacgtaga agttaatgct gttacaacaa aggcagaaaa cggtttccac
    75301 cttccatcta aagaagaaat attgtctaaa gtagatgata aaactaaggc tataattctt
    75361 tctaacccag gaaatccaac tggtgcaatt tatacaaaag aagaacttaa tatcctagct
    75421 gaaatagcta aagaaaaaga tttatggata atagcagatg aagtttatag agaatttgtt
    75481 tatgatgggc ttgagtatac aagctgtggt aacttagagg gtgtacagga tagagttata
    75541 ataatagaca gtgtttctaa gagatacagt gcttgtggtg ctagaattgg ttctatcgct
    75601 tgcaaaaata aaggtcttat cgctcaaatc cttaaattat gtcaaggaag actttgtgtt
    75661 cctacattag agcaaatagg agctgttgag ttatacaaaa ctcctgtttc ttacttcaaa
    75721 gaagttaatg aagagtacaa aaaaagaaga gatgtattat acaatgaatt aatgaaggtt
    75781 gaaggtgtta tatgtaaaaa accaactggt gctttctata tagttgctaa attaccagtt
    75841 gaaaatgcag aagatttcac aatttggatg ttaaaagaat ttaacaaaga taatgaaaca
    75901 gttatggttt gccctgctga aggattctat gctactccag gtttaggacg tgatgaaata
    75961 agattagctt acatcttaaa tgaaaaagac cttcatagag ctgctacatt attaaaagaa
    76021 ggtttagagc aatatgtagc tttacaaaaa taatttttta aacttaattt atataaattt
    76081 aatgatataa aatgtcccct tttcagatat tatttgaaaa ggggacattt cttaattaat
    76141 atattaatta agacttagac ctgactattt ttcattttct ttatatagtg ttggccagta
    76201 atctttattc actttaatta aagcatctaa aacttgtctt gccttagttg gagagattat
    76261 agttctattt aatgttaaag ataaaatagc tttttcataa gattgttcaa agtatgcatc
    76321 aactgctaac ttttcataag ctagttgacc ttctaacagt cccttataaa atgttggtat
    76381 attacctaca tgtaaaggtc tcggtccatt ctttgtaaga atcgcagcta cttctaccat
    76441 tgcatcatca ggtaagttgc taatagcccc attattttct gttataacta tggctatttg
    76501 gtgtttgtta tgagctattg cttctgcaac ttcaactata aattccccat gagcatcatt
    76561 atgcactaaa ttagaaccta tagatgttcc tttttctata acagatttac attcttcaaa
    76621 tacacgcttt tctcttccat tcataacttc tcttgctcta gtacaattta tatttgattt
    76681 agctactttt ttatcaggat atagataata ctgtacatat gtattaggta agtaatctgg
    76741 tacatcttcc aacatatctt taaccattcc ataagtgtct aaccaagatt tatctctttg
    76801 ttctgcatca acaggttgga atccagagtt tgctactaaa tcttttatct taggtaccaa
    76861 atcttcacca tttttatcat acaaatgtgt aaaccatcca aagtgattta atccaaagta
    76921 tacaggctca aatgttcttg aatccatgtc taacaatctt ccataagacc ttaacaagtt
    76981 aactggttgg tcacacatat taagtaatct tttatcatct ggaaatactc tttttaatgc
    77041 ttctgcaaca atagcagcag gatttgtata atttaatatc catgctttag gagagtattt
    77101 tcttacagtc ttaaccattt ctatcatatc acctatagac cttaacccat aagcaaatcc
    77161 accagctcca caagtttctt gaccaaccag tccaaattgt agaggaatct tttcatctaa
    77221 ttctcgcatc ttaagaccac cagttctcat ttgaacaaat acaaaatcta catctataaa
    77281 tgcttcatct gggtttgtag tatattcaag tgttgcttta ggatattctt ctttaaataa
    77341 tatttttcca aattccccta ttaatctttg acgttcttct actacatcta acatagttac
    77401 tttatttaga ggaaatctat cactcatttt acataaagac tttaaaagtc ctggagtcca
    77461 agtactgcct cctccaacta tagctatatt gtatcttttt ttcattgtca tattaatcac
    77521 ccctgttttt tattaactaa cttgtaagat gattataata tataaagttt tctacatgaa
    77581 tacttttagg taatcattaa aaatagttca attttagtat ttttttcaaa attgtaattt
    77641 ttttcatcta ttgtattttt caatgtattt atgaaacata tattccataa gagaaagtgc
    77701 tggcactcta gatgtatagt taacactatt aaaattatat tgtggagaag atacaaataa
    77761 ttttatatca gctatatttg ataatgaatt gacacttata tttgtcagag aaattacttt
    77821 aacttgattt gtttttgcta tattacatgc cttaataact tgagcagtct ctccagacat
    77881 agatacagca attacaaggt catctttagt aatatttgat gcagccaaat acatgagagt
    77941 tgaatcatca tagtatttta catttacacc tatagctgaa aaacgttgag acatttcagt
    78001 acatactaat ctagaagacc caacaccaaa aaaatatata tgcttagaat tatgtatttc
    78061 atttaaacac atatctatat tctctacatt tattaaattt tgtgtatcca taacatcagt
    78121 aaaaatatca ctttgacttt tagtaaactc cttatttctt tcatttctat ttgaatatga
    78181 aaaaactaaa aagtttttaa attcactata tccagaaaag ccgagcttct gacaaaacct
    78241 tactatgtat gcagtcgaat taaaagtttc atttgctata tctttaatct ttttttgatt
    78301 tattttttca gaatttttta gaaaatagtt taaaagagat atttcatttg tagataattt
    78361 tttttgattt atatctaatt tgtctattag gttcatttat acctccataa taatgatttg
    78421 tagttaaaca actttctcat atttattata taaatataca ctatacagca tttatcttat
    78481 gtttattata ctataaaaaa gacaatacaa attataaatt agtattgcct tttaatattt
    78541 actttaaata gacattgcaa aagaaacttc gtctcttact tgagatacag atggcccata
    78601 aattatttgg atatctttat cagatacttt tataactccc attgcacctg tatatttttt
    78661 aaaagcattt tcatctactt tactcatatc tttaactact actcttaagc gagttataca
    78721 gtttgttata tcttctatat tgtccttacc acctaaatat ttaattatag ataatgctct
    78781 cttagtagtt tctccacttt gagctatttc tactttattt gataaaggtt ttaaatcaaa
    78841 atttatatct gttatttctt ctcgtcctgg agtttgtaag ttaaatctaa gtatcaaaat
    78901 cttaaataca ttataataaa ctattgcata cactaaacca agtattatag aataaatcca
    78961 ctttgtattt ggttgcataa ctccaaatac tactaaatct attatgccac cttgagtatt
    79021 tcctattgct actccaaata tatgcatcat cataaatgat atacctgata aaaatgcatg
    79081 tataacaaat aatattggtg atacaaataa gaatgaaaat tccaatggtt ccgtaattcc
    79141 tgttacaaat gttgctaaag caccagctag taatatacct ttaaccttcg acctattttc
    79201 aggctttgca gttttataca tggcatatgc agcagcagga agaccaaata ccattatagg
    79261 tattttccct tgagctaaaa atctagttgc ttctgttgaa aaactgattg tttcagggtc
    79321 acttagttga gctaagaata tgttcaatgc tccaaatact tcttgccctc ccacaactaa
    79381 agaacctcct acttcagtaa atctaaacat agcatttaat atatgatgta atccaaatgg
    79441 tattaaaagt ctttcaagaa atccaaatac aaatgttcct aaatatccta aactagctat
    79501 accaatacct acactctgaa taattgtatt tacatatggc catatatatg gtattattat
    79561 ccccaaaata gagaatacta ctgttgttat tattggaaca aacctagttc caccaaagaa
    79621 tcctaaataa tctggcagtt ttatattata gtatttatta tgtaatgatg ctgttattat
    79681 accaactaca attccaccaa atactcctaa ttctaatgtt tgtatgccta aagttacagc
    79741 ttgacccatt tctctcatca tgtcaggttc agcaataatc cccctacacc ctaacatata
    79801 atttacacta gtgtgtaata ctaaataacc aacaaaacca gaaaatgcag aaactgcttt
    79861 ttcttcttta gcaagaccaa cagatattga tatagcaaag aatattgcta agtttccaaa
    79921 aagtactcct gttatagctt ttgtaaaacc caatattcct tgaataaaat tatttgctaa
    79981 aaaaggcata tcactaacta tattaggatt tgaaaatgct gaacttattc ctaaaaatat
    80041 acctgctgca gatattaatg ctattggcaa taaaaatgat tttcctaact gtaaaaagaa
    80101 ccctttcatt ttttgtttca tttctatccc tccattttta aatttttaaa acgttttcta
    80161 tgtcataatt atatattttt attttgtttt tgaaacttta taatttgttt taaaatattt
    80221 ttacataaat agtaattttt tcaaaactgt aaattttttc aaacaaagac atagtaacgt
    80281 tgtaacatat ataaatttaa aaagagctta gaaaataaaa ttattgaata taaaatggaa
    80341 aaatataaat tacacaaaga gatatgagta cgtactaaca aatacgaaaa tgtataagaa
    80401 attataaaaa agtacatcaa gaaaatttaa gatgtacttt ttagattgta tttagactta
    80461 taattatata gttaaatgaa taacaaagaa ttaatcttag tactattaaa tacaaaaatt
    80521 tttatatttt ttctatctaa attcttcttt gtttaatata tattgaagag tatttattgc
    80581 ttctaaatat ttttttctgt cttcttcagt taatttagaa agtttttctc ctaaaccatc
    80641 acttaattta tccataaaat cagttgctat cttatctccc tcttcagtaa tgtcaattag
    80701 atattttctt ctatcaacta aatctctttt ccttgttaca tacttcttat cagttaaatc
    80761 atcaaccata ctagttaaac tgcctttttc tatatttaac ttagagcata aatcagtcat
    80821 acttattact ccataatttt ttatgaaaac taatgctctt aattgtgttt tatttacatt
    80881 ataatctggt gcaaattttt ttaggtcttc taagtacagg ctagaataaa tcttaggaaa
    80941 tgtttttact aaaaaactta tggtatcttt tactatatag ttcatataat cacctcggtt
    81001 gttttaaaat ttattaaatt atctaaataa ctttatttca gtttacatta aaaatattgc
    81061 aagtacaata gtttttgctg aatgtttaaa tttaattagt aatcttatca tttttttatt
    81121 tttatttata ttattcctat taaatattat ttatatagct attttattaa attcatggta
    81181 tagtaagtaa agaagaactc ttcacagcgg tggagagaag acgctagccc attaaaatgg
    81241 ctatcttatt tataaataag atagccgttt ttaattatat tttatctgta caattctata
    81301 ctcttaagtc tacatctact tttcctaagt cttccttata atcttttata gcaggttcta
    81361 caacttcatt tacaaattct acaacttgtt ctggagctct acctataaag ttttttgggt
    81421 ccattataga tagtatttct tccttgctca ttttaaatga atcatcattc attataagtt
    81481 caattaagtt attatccttg ccttcatgct ttactctata ggcagctttc atagaatatt
    81541 ctcttattat ttcatgtaat tcctgtctat ctccacctct ttttacagct tccataagta
    81601 ttgtttctgt agccataaaa ggaagttctt catttacacg tctatttatc atattttcat
    81661 atactactaa accatcagtt acatttatcc ctatttcaag tatagcatct gctgccataa
    81721 atgcttgagg tattgccaat ctcttattgg ctgagtcatc taatgttctc tctaaccatt
    81781 gagtggcttg taccattgca gggcttatag attcagagat tatatactta gataaagatg
    81841 ctattctctc acttctcatt ggattcctct tataagccat tgctgatgaa cctatttgat
    81901 ttttttcaaa tggctcttct aattctttta aactttgtaa aagtcttata tcattagtca
    81961 tcttatgcat actttgagct atccctgata gtatgcttat tacttgataa tctaactttc
    82021 tagtatatgt ctgtccactt actgcatagg aagaatggta tcccatcttt ttacaaattt
    82081 tcttatctaa ctcttttact ttttcgtggt ctccttcaaa taagcttaaa aaacttgctt
    82141 gagtaccagt agtaccttta actcctctta acttcatgtt gtctattcta tagtttaaat
    82201 cttccaaatc aagaattaaa tcttgagccc ataaacaagc tctttttcct actgttgtaa
    82261 gttgagcagc ttggaagtgt gtaaatccaa gagctggcat atctttgtac ttaagtgcaa
    82321 attcttttaa attgtttatt aaatttacaa gctttactct tagaagtttt aaagcttcat
    82381 tcatttgtat aacatctgta ttatctccaa catatgcaga tgttgctcct aaatgtatta
    82441 ttcctttggc tttttcacat tgtaaaccat aagcttttac gtgagacatt acatcatgtc
    82501 ttacttcttt ttctattttt ctagcttcat caaaatttat attatctata ttagctctta
    82561 gctcatctaa ttgttcttca gttatattga ttcctaactc atgttcacct tctgcaagtg
    82621 caacccataa ccttctccat gtagagaatt taaattgtgg agaaaatata taactcatgt
    82681 ccttgctaca atatctgtct gtaagtgggt ttgagtaagt agtatattta ttatctatca
    82741 ttatattagc accttcctta aatcttttgt cgtgtgatta ctgtgtacac attagtacat
    82801 aaataattat atataatttt acgaactata acaagacttt tttatttttt gttcacattt
    82861 atatatagta ttttttattt attactattt tttatttata tccaaattat ctttttcaat
    82921 taagtaatcc actatttcac tatcaacaaa atttaataca tacttatatc taattgcata
    82981 gtatttatca ctccatccaa gctgattttt tacatcactt tcatctgccc caagccttaa
    83041 acttattgct gcaaatgaat gtctaaaatc tcttgctgaa tattgagaaa gtccagctaa
    83101 atctaatgct tttttgacta taagtctgac atttctatct gttatagaat tactcttttg
    83161 agttgtaaaa ataaaatcat cactaggtat tattacctct ggaagcccag aataattcct
    83221 gtaatcttct aaaagtttaa aaaagtatgg atgtaattta actactcttt cttttcttcc
    83281 cttacctaac cttacatatg agttatcgtt ttcatctacc ataaggtctt tccactttaa
    83341 gctaactaat tcatttaata aacacccagt agtaactaga cagactatta ttactctatc
    83401 tcttatattt aattttggta ggatacctat aagtttattt atttcttgta tacttagaac
    83461 atcatctttt gtttttattc ttgttactgt gggtttttct acatatctaa atggatttat
    83521 atctatgtat ccttcttttt ttaagaagtt ataaaaacta tgtaaataac tatatatctt
    83581 ttcacaagtt gatttcgcat atttagtctg tatatagtct acaaaatttt tacaatcttc
    83641 tttcgtagca taaatcaatt ctttcccttt taaaaattct ttaaacagta taacctttga
    83701 taaataatcg tgtttcgtgt ttggatttaa ttttgtagaa aaaacattaa aagtttcata
    83761 ctcataatca tctagtattt ttgtactata cataataact cctttccttt tcataaaata
    83821 aaatagctat acttttacta taccatatat ttccccctca aatatacccc ttattcaata
    83881 gataactttt aagtttattt tgttatattg tgaaggtttt atgaaaatat caatcttcca
    83941 ttgtgcacta cacagtacta tggtattata agttagtaaa aggtggcatt tttttattaa
    84001 tctatgaata aaatatgcta ctataaattt gtattggagg tattttgatt tggaaacatt
    84061 tagtttgctt gaaattttta aggcagtcat tttgggcata gttcagggaa taacagaatg
    84121 gctaccagta agtagtacag ggcatatgat attagttgat gagtttataa aattgaattt
    84181 ttcaaataca tttataagta catttttagt tgtaattcaa tttggttcaa tattagctgt
    84241 acttgttata ttttttagaa aattaaatcc ttttgatagc gcaaagaata ttaagcagaa
    84301 aaaagaaaca gtccgtttat ggcttaaggt tataattgca gttataccat ctggagttat
    84361 tggaatactg tttgaagatg atatagatag attattcttt aattcaacag tagttgctat
    84421 tgctcttatt gtatatggta taataatgat agggcttgaa aagagaaata aaaaacctaa
    84481 gtataaagat ttttctcaag ttacatataa attagctctt tgtataggat tattccagtg
    84541 tctagctctt ataccaggta catctaggtc tggttctact ataataggtg cagtattact
    84601 tggtacttct agatatgtag cagcagagtt ttcattcttc ttagccatcc ctacaatgct
    84661 tggagctagt gcattaaaac ttctaaaagc tggatttgga tttactggat ttgaatggct
    84721 tattttaggt gttggttctg tagtagcatt tgttgtttca attgtagtta ttaaattttt
    84781 tatggactat atcaaaaaac atgacttcaa agtatttggt tattatagaa tagtcttggg
    84841 tatagtggtt cttgcttatt tctttctatt ataatgtatt ctaatttaat aacaaatgat
    84901 aaggagaaaa gttatgagtg ttaaaaaaga aatatttgat tggattaagt caatagctat
    84961 ggctattgta cttgcatttg taattctaca atttataaga ccttctattg taagtggaga
    85021 atcaatgtat cctactttag atgataaaga ttatctgatt ttaaatagga tatcatacaa
    85081 ggttggtaaa cctgaaaaag gcgatattgt agtttttaaa accaatttag ttgatggaga
    85141 aacaggaaag aaaaaagact taataaaaag agttatagct actgaaggtg acagaataaa
    85201 aatatcaaat tctaaagtgt atgtaaatgg aaaattatta aatgaaccat atatacacaa
    85261 taactatact tctggagata tagatactgt tgttccaaaa ggtaaactat ttgcaatggg
    85321 agataataga gaaaatagta atgatagtag attccctgat gtaggtatgg ttgatgaaga
    85381 tgaagttctt ggtaaggtta tggtgagact attacctctt gataatattg ggaaagtaga
    85441 ctaaaaaata agagactgaa ttggtaaagt ttattttaca aatctcagtc tctttttatt
    85501 ttcttaaatt acaaatattt ttttactaaa tatcttttga ttctgtaata agtcttatta
    85561 tatcacttgc ttcttcatta aaagttgtta ctatacttag gtagtctgtt gctctactca
    85621 tagctaaata aaccttattt aaatctccta caaagtcatt tacttgataa tcttgttcaa
    85681 tatcatttat agtttgattg tataacatct ctaattcaca tactattacc gctttatact
    85741 ctaaattctt tattgcatat atatttgcta ttgtagttcc taccttctta cttatatttg
    85801 tcaaattatc ttctgcacat atataaggaa tttttgcctc ttccaatgct ttttttaaca
    85861 tatattgaaa gtaaatggtt tttccacttt ttaatttctt cttattgtaa ggataaacga
    85921 tagcaacttc agaataatca agaccttttt tacttattaa atactcaatt tcccagatta
    85981 cagaacttat ttggtcatca aggtcactta cttttattat atcaacagac ttatttccac
    86041 ctctaagtgc tttagtataa aagaaagtac taaattctgt atttggtctt aattcgttga
    86101 tatatgagtt agaattattt gaaaatttat ttgtaaaatc tacaatctct ttagcttgtc
    86161 tataattttt acttaagata atcttatcat caaattctat accattatat aattttttaa
    86221 atatattcaa tctattagag atattcaagg agttacaaga acacacatta aatatgaatt
    86281 ttgttttata taaaaactcc cttataaaat ctatttcata ctctaaaaag ctttctgctt
    86341 catcaataaa aatagccttg aacatatttt tattttttat aatgttctgt gcttgtttta
    86401 caagattatt aaaggtcttt tcgtaatcat tttttaacat gttataatct acaattaaat
    86461 tgaatttttt agctagttta aatataaaag aactaaatgt gtgaacttct aaattgttat
    86521 tatctttgta taataactct atcctctctc gaagctcatt gcacaattgt tttgtatgtg
    86581 taaatatgac taatttatga tgtggatata cttttgctaa ttttatagcc ctagaaagca
    86641 taattgctgt tttgcctata ccagaaccac cttcaataag tgtattccca tatttaatag
    86701 aaacaacatc tttaatttga acgtcttcca tcatagttgc tgtatactta tagtcatcat
    86761 tgtagaatga aattttttta aatttttcat ttagatgaag tttatcattt attatatagt
    86821 attctgaaca tatgtctagt aaaaataaat ttaagtttat ttcatcattc tcatcattaa
    86881 gatattcctc cagcgaaccc ttattcatta tatcttgaag cttattttta tctattatat
    86941 tattattaac aaattcttca aattcatatg tttcctcaac ttcaacgtat ggcataatgt
    87001 aaacgtagtt ataacttata tttctattct tttgtcccat ttttagtttc aaaagttcat
    87061 attcctcatt cataacttca agtaactctt cttctaaaat aaaaaatata tcttctgttg
    87121 tatccataaa ttttataaat aaaattcttc catctttaac atacaacaaa tcggtattta
    87181 ttcctttaaa aggagtaact tttggcacta ctttaacgtc ctcattgata ttttcgtaaa
    87241 atattttctc gaactccttc aattttaggg cgtctaactg agaatttata tttatgtatt
    87301 ggctcactta cattacctcc ttctgttata cttaattata ccattttgaa ctatattttt
    87361 atatatactt tttataggca aatttagtaa ataaattcaa aataaataca aataaataca
    87421 aaactgctaa aaaaattttg caataagtat agatatttat tgttataaaa tactttctgt
    87481 aaataataaa atgataaatt tcataattaa tgcttaaaat aataagtaaa gtcttaaaaa
    87541 aaataaatct tgttagccaa aaataagatt tattataaaa aatttaaaaa cctactaaaa
    87601 ataatctatt ttcattagca ggttttattt ataatcttct tatattaata ctattatatc
    87661 ctatttttag attttactgt agtatttact atttattttg tagtaaagta ttgattttac
    87721 aacttcatta tatcaaacaa acttggataa ttatataaat aatacatata taaagcttta
    87781 ttttattaat cttttgtaag tagcactttt agcacttaga ttatttttgc attatataaa
    87841 attaaactta aacaatttaa aagccacaag atatattatc atatcttgtg gcaaatttaa
    87901 atttctaaaa atattttctt attatttaga tattatttct tttacttcgc atactctata
    87961 gctcttgttt ctcttattat gcttactttt atttgtccag gatattcaag ttcatcctct
    88021 attttcttag tcatatctct agccaataga tgtatttctt catcatttat agcttctggt
    88081 tttaccatta ttcttatttc tctaccagct tgtatagcaa atgatttttc tacaccttca
    88141 tatgaattag ctatttcttc taatttttca agtctcttta tatatgcttc taaagtttct
    88201 cttctcgcac caggtctagc agctgatatt gcatctgctg ctgtaactaa tacagcctct
    88261 actgtttgag gctcgtaatc tccatgatga gtactcatgg catgtataac ttctttagac
    88321 tctttataac gtctaagtaa atccatacct atttcaacat gtgtaccttc catttcatgg
    88381 tctacagcct tacctatatc atgtaataaa cctgccctct tagccaatct aatatctgct
    88441 cctatttcag cagccattat accagctata tgagcaactt ctatagaatg tttaagtaca
    88501 ttttgtccat aactagttct atagttaagt ctacctaata atcttattaa ttccggatga
    88561 atcccatgta cactagtttc aaatgcagct tgttcaccat attcttttat aatattgtca
    88621 acttcttttc tcgccttttc aaccatttct tcaattctag ctggatgtat tcttccatct
    88681 gctattaatt tttctagagc aattcttgca atttctcttc ttattggatc aaatcctgat
    88741 aaaattacgg cttctggagt gtcatctatt ataaggtcta tacctgttaa ggtttctaaa
    88801 gtccttatat ttctaccttc cctacctatt attctacctt tcatttcatc attaggcaag
    88861 cttactactg ttacagtagt ttcggctacg tgatctgctg cacatttttg aattgcatat
    88921 cctataattt ctcttgattt cttatcagct tcttctttag cttgactttc tatctctttt
    88981 atcattatag acatttcacg tcttacatct ctctccgcat tggttaagat gatttctttg
    89041 gccttatcag aagtaattcc tgatatactt tctaattttt ctaactgttg agtttttatt
    89101 acttcaactt cttcttcttt cttttccact acctttaatt tttcacttag gtttacttct
    89161 ttagattcta aattttgtaa ttttctatct aagacttctt ctttttgtac tactcttttt
    89221 tcatactttt gtacttctgt tcttctttct ctgttttctc tttcagcttc tgttctccac
    89281 ttatggatct cttctttagc ttctagtaat ttttcttttt gtactgtttc tgagtcgtgg
    89341 tgtgctttat ctattatttc tttggccaag ttttcagctt gtccaatttt tgcttcagat
    89401 atattttttc taacaaaata tccagctata ataccaacag ctgcacctat tacaatcatt
    89461 actacactat ctatgacatc cacctccttc gttaataatc ccaaaatgtc atcactatga
    89521 ttaaaaaata ttcctaataa ttaaaattaa atttagatat tttatcctca cttaatttta
    89581 taattttttc aacattgtgt caagctaata gggagcgtgg catgtcttta attactagtt
    89641 atttttttgt atttttactt attcttctac aatttctttt gatactgaaa tacctgattc
    89701 ttcatgttct tcatttaaat tgtaaaatgc tctaactttc tcatctattt cagtagttaa
    89761 atctaaatta tcttccaaga attttttaac attttctctt ccttgtccaa gtttagtatc
    89821 attgtaacta taccatgaac ctgatttttt aactatatct acatcagcag ctatatctaa
    89881 aaggtctcca atttttgaaa ttccttctcc atacattata tcaaattcag cttgcttaaa
    89941 tggtggtgct actttgtttt taacaacttt aactctagtt ctactaccta taactttatc
    90001 accttgtttt attgtatcta tttttctaac atccaatcta actgatgaat agaattttag
    90061 tgcacgtcct ccagtagtag tttccgggtt tccaaacatt attcctactt tctctcttaa
    90121 ctggtttata aatatagcaa cacaatttga ttttttaatt gaaccagtta actttctaag
    90181 tgcttgtgac ataagtctag cttgtaaacc tacatgagaa tcacccatat ctccatctat
    90241 ttcagccttt ggaactaatg ctgctactga gtctattact attatatcta tcgctccact
    90301 tcttatcaat gcctctgcta tctctaaagc ctgttcacct gtatctggtt gagatattat
    90361 taggttatca acatccacac ccaaagcttt tgcatatact gggtcaagtg catgttctgc
    90421 atctataaat gcagctattc ctccatcttt ttgagctgat gctacacaac taagcgcaac
    90481 agtagtttta ccagaagatt ctggaccata tacttcaact attctccctc taggtagacc
    90541 tcctatacca atagctatgt ctaaaccaat cgctcctgtt gatataacat ctatagacat
    90601 agatgttgct tctcccaatt tcattactga acctttacca aaatcttttt caattttacc
    90661 taaagcttca ttcaacgctt ttaatttttc ttgatctaca ctcatctcta taccatccct
    90721 tcatttatct acaaacattt gttctcttgt tatatattaa ttatataaca taaatcaaac
    90781 ctagtcaatt taaaaacgct actaatgatt atatttttat tcattacatt ttatttataa
    90841 accattatta ataattatat acacaaaaga aaatattctt aaaatgaaaa gaggtatact
    90901 ataatagtat accctttttt acatttttaa aattttaagt tgttattttt tatttattaa
    90961 tcattagttt ttatttatta aagcataatt ttttacttag aagacataaa aagctcttta
    91021 tttttatata gatattccca tccagaatat aatgtaagta gtgtagctat aagaatgaga
    91081 atttcaccaa tatttaatat caatacattt tcaaactgag cacctaacaa taaaaacact
    91141 atagatacca tttgagttat cgttttaagt tttccactgt ttccagcagc aattactttt
    91201 ccatcagcag cagctatagc tcttaatatg ctaactgtaa gctctctagc cactattata
    91261 attaccatcc aactacttac aagatggtct tctatcatac atgtaagtgc tgaaataacc
    91321 aataacttat ctgctaatgg gtccataaat tttccaaagt cagtgactag attgtatttt
    91381 ctagctattt ttccatctaa agcatcagta attgaagcta ttataaaaat aatacaagct
    91441 attaaaaatt tatttggtac attgagcaac ataattaaaa caaatactgg tattaaaaat
    91501 attctaaaca aagttaactt gttaggcaag ttcatataaa acatctccca ttaaatcgta
    91561 ttccattgca tcatttattt gaacacttac aaattctcct acttcaagat tgtctacact
    91621 ttttacatac actatactgt caatttcttc tgcatcacct tgtgttcttc ctgtatatac
    91681 attatcttct atctgttctt ctattaacac ctcataagtt tttcctatct ttttgtcatt
    91741 aagttcttca gatatttttt gttgaatcat cattaaagta tctcttcttt gtatttttac
    91801 ttcttcatct atatggtttg gcaatctatc tgctggtgta tcttcttctc ttgaatatgc
    91861 aaatgcacca agtctatcaa atttaacctc ttcaacaaag tccacaagtt gtttgaagtc
    91921 atcttctgtt tcaccaggaa accctactat tattgtagtt ctaagtatag catctggtat
    91981 attacttctt atcagattga ttttatttaa tatatcttct ttagtagttt ttctattcat
    92041 taattttaaa atattgttac ttgcatgctg tattggcata tcaaagtaac tacatatatt
    92101 atcatatttc tttataactt gtatcaattc ttctgttata gattctggat atgaatacat
    92161 aacccttatc cacttaaatc catctatttt tgcaagttct tctaaaagtt ctgataatct
    92221 ttcttttcca tataaatcaa aaccatactt tgtcgtatcc tgtgctataa ccacaagttc
    92281 ttttactcca gattcagcta atttcttagc ttctttaatt atatcttcaa attttctact
    92341 tctatattta cctcttagtt ttggtattat acaataagta caattattgg aacatccttc
    92401 tccaattttt aaataggcca tatagctagg tgtagatata tatcttggta aatcttcatt
    92461 aaatacaaac tctatatcat taaggcttac aatttgatgc atttcactta attctttaag
    92521 tattttatct atattttgat agcttcctgt tcctactata gcatctattt caggaatttc
    92581 agtttttaat tcttcagaat atctttgggc tagacaccct gttactatca acaacttcaa
    92641 attgccagtt ttttttaact ctgcaaagtt tattatcgta tctatagatt cttgtttagc
    92701 tgactctata aacccacatg tatttactat aattacatca gcttcttcaa aatctccaat
    92761 taatttatag cctttgttat ttaaaattcc catcattatt tctgcatcta ctaaattttt
    92821 tgagcatcct aatgattcca atgctatttt taacattcac tttctccttc caatatactc
    92881 tcatataagt ctataacatc ttctaaagct ttttgtgtat cattaaaatt tataatctta
    92941 ctatacttat atttctctac tgaatgcata taaagtgggt cgtagtattc taaaagatat
    93001 ctttttacaa gttctttata ttcacctgat tctaataaat caatataatc atctactact
    93061 ttattaccca atctttttct aaacttgttt atacattctt ttaaaatcaa tatattacct
    93121 tcatctttat cataaatata atctctacaa agtctatcaa ctctattttc aatatcacat
    93181 tctaataata tatgatgtcc ttctcgtgtc attgcctcga aaatttcatt tggaactgta
    93241 acacttccaa ctcgtttgct ttcactctcg acaaatatat aattctcttt cgaaaaaaat
    93301 atactttcaa atagttttgt ttcaaagttc ttttgagatg gtggcttttt atcaaaagtt
    93361 ataaaaccaa aggtagaacc actgttttta gctatgcctt ctaaatccag cacgtctatt
    93421 cctttttcat ctaataaatg taacaaatca gtctttcctg taccagtcaa tccatgaaca
    93481 gatacaaagt tttttgtatc cattacatgc cttaaatact ctaaaacaaa atttctataa
    93541 gccttatatc caccttcaag ttgatataca tttacaccta atgatgataa taaatttact
    93601 atactgccac ttctcattcc gcctcttgca caatatatga caatattatc ataatttaat
    93661 gcaagttctg ctgcttgtaa atatatatcc tttaatttat acgatacata gtcaaatcct
    93721 ttttgtattg cttcatgttt tccctgcatc ttataaattg ttccaacttc attatgttca
    93781 ttatttttaa aaagaggcat attgattgca ttcaatatat ggtcttcttc atattctcct
    93841 tcagttctca catctacaaa tattacttta tctagcttaa gtgctttttc tatttttata
    93901 actgacaatt ctattcacct tctaaattct gcaaatcctg tttgcttatt aatacctttc
    93961 tcggtttact tccctcactt gctccaatta ttcctctttc ttccatagaa tctataagtc
    94021 tagctgctct attgaatcct attttaaatc ttctctgtag catagaggca gatgcttgac
    94081 cactttccac gacaaattct atcgcttcac tcaaaaactc atcctcatca ctaccctttg
    94141 aagtattaac cttagatata gtttcaatta tatcttcttc atattttatt ccatctttaa
    94201 cctgactttt tacaaaatcg attacttttt ccgactcact ctctgatatg aatgcccctt
    94261 gaagtctaac tggttttgct gcaccaagtg gatagaataa catatcacct ttacctagaa
    94321 gcttctctgc accacccata tcaaggattg ttcttgaatc agtttgagat gatactgcaa
    94381 atgctattct agatggtata ttagccttta ttacccctgt tataacgtca acagatggtc
    94441 tttgagttgc tacaatcaag tgcattccag cagctcttgc catttgagct aatctacaaa
    94501 tataatcttc tacatcattt gcacttgcca tcattaaatc tgctaactca tctattatta
    94561 ttactatttt aggaagtttt tcttccgctt tctcattata acttgttaca tcttttactt
    94621 gagcatctgc aaataatttg taccttctat tcatctctgt aactgcccaa tttaaagcat
    94681 ttgcagcttt tttagggtca gtaactactg gtatcaatag atgtggtatt ccattataat
    94741 ttgcaagttc aactactttt gggtctatta atagtaattt tacttcatca ggatttgcct
    94801 tatataaaat actacttatt aatgtattta cacacacact ctttcctgaa cctgtagaac
    94861 cagctattag taagtgtggc atcttaccta tatctccaat tataattttt cctgctacgt
    94921 cttttccaag tcccattgca agaggagagt taaaattatt aaattcttca ctttctagaa
    94981 cttctctcac accaaccatt tgagcttctt catttggaac ttctattcca attgcacttt
    95041 taccaggaat tggggcttca attcttatac ttttagctgc taaacttaaa gctatatcat
    95101 cagttaaatt tacaatttta cttaccttga ctcctggact tggttgtatt tcatatcttg
    95161 ttatagtagg tccaactgta acttgattaa tttttgcttc cactccaaaa tctgatagtg
    95221 tcttttctaa aagagaagca tttttcaaca ctttcttttt accattttca tcagacttct
    95281 tatttacttt atttaaaagc tcaatgctag gctttttata gtttgaataa tcctcattaa
    95341 ctggctctgc tacaatactc ataggttgag ttttttctat atttaaatta ggtttagcta
    95401 tatcaacttt tttttctggt ttagtatcta caactggatt ttcattggta gctttttgta
    95461 attcttttaa aacatctaac tctggcatac tttgagttcc ttctaatatt tctaaatact
    95521 catcttctgc cttattaaat ccaactattt ttatagtttt atcatctaca ccatcactat
    95581 tttcttcttc aaaatattca tcttcttcat catcattatt aagacctttt gacattaacc
    95641 ctttaaagaa acctggtttt ttatttatag tagtatcatc tacttcatca gtcatcatat
    95701 ctattgcaga ttttttcata tttgcaattt tatctttaaa cgttaaattg ctgtctttag
    95761 atgctttaga ttttgatttt gcatttgaca ccaaatcttt tatagaaata ttaaatataa
    95821 acattacaga aagtataagt gcgaagatac ttattaacca tccacctgct ataccaaata
    95881 ttttactcat ataatacgca atagttgttg ctatcaaacc actaccttgt ccacttacac
    95941 ccaatttcat aacatcatca aacatgttac cttttagtgg gctatctaca ggaagagttc
    96001 ctgcatttaa taatccataa aatacaaata taaataaaat aattatgtag tatagtttag
    96061 tctttcttag cctatatata tattcatttc catcaaaaaa tcctaaaagt cctgttataa
    96121 ttactataaa tggtattgct attgaaagcc ctccaaatag tcccttaaaa agattttgca
    96181 ttaacacagg tatccatccc atagaattag aatttaaact atataataaa aatacaccta
    96241 taaatattgt tattaaatta tgatattctg cattaaaact taaggtattt accttctttt
    96301 ttttcttctt tttcgtggcc attaatatca ctccttattt ttagcaagtt ttaccccttc
    96361 acagcaaaaa gtgctaatgc cttaacacta acactcctac tttattacat cattatatca
    96421 taaattttat tatttaaaca aattttaatc attatttttt tcttcctcag attcttttat
    96481 aagctctctt aattttttaa gtgcttcttt tagtcctcca acttcatcta taagaccata
    96541 atccacagct tcttttccta ttaatacact accaacatca cttacaagtt catctttttc
    96601 atgcataagt ttttcaagta catctttttt gatatttgat gttcttatta taaattgaat
    96661 tattctatct tgcatctttt taaaatattc aaaagtctca tttataccaa tcacaagacc
    96721 agtagttcgc actggatgta taatcatggt tgctgttggt gctataaatg agtaatctcc
    96781 tgctgtagca agaggaacac ctatactatg acttcctcct agaacaagag taactacttt
    96841 tttagatgta ctgtttaaaa gttctgcaat agctaaacct gcttcaatat ctcctccaac
    96901 agtgtttaaa acaactaaca ctcctttaac atcattactt tcctcaattg agtatagcat
    96961 tggaattata tgctcgtact ttgtagcttt tttttgagga tttcctataa aatgtccctc
    97021 aatttctcca attatagtta tacattgaat atctttagga ggttgaggtg gcatttcatt
    97081 ggtaccaaat tgctttatac attctctctc ttcgcaacta gattcttcac tacaattatc
    97141 tttatcaaat ttttcattat cttctctata atctttcata aaaaaactcc tatcaaaatt
    97201 atatttaatt tagttttacc aaataaatca aatatattaa gatatatatg aaattcttaa
    97261 atttgattaa aaaataattg tattatacag tttattttaa ataaaattgt tggtgtatag
    97321 catgtactgc tgtatgcata tcttcttcac taactaaaca agatatagtc atatttgagt
    97381 ctgatgtttg taaaagagat acccctgctt ttgataatcc tctaactacc tttgacatga
    97441 taccagacat ttcatcagca attcttgaac atatcaatgt taccttagca cagtctctat
    97501 ttacttcata atctaattca aatttatcta gtatttcctt taatgatttt atatcagcat
    97561 cttctacaac aaatgctttt tctgatataa agaaatttat catatctata gttataagtt
    97621 tcttttctat ctcatttaat acttctgtaa acacttcttc tgctgactta atcttaactt
    97681 gtgctacgct atctttattt gcaacagcaa ccttaaaatc tctttcttgt tcatattcta
    97741 tattgtcttc taagtgtcta cataaagaac ctatttttgt accttcaaaa gttggattca
    97801 ttgtattctt tatggctaaa gttatatttc cacttttagc caactgtact gctcttggat
    97861 gtattacttt tgcacctttg tcagccattt ggaatacttc ctcatagtct ataaaactca
    97921 atactttagc gtttggttct actctagggt ctgcagtcat tataccatcc acatcagtgt
    97981 aaatttcaac tgtttcacat tctaaagctt taccaatagc aactgctgat gtatcgcttc
    98041 cgcctcttcc aagagtagtt atttctccat catctgttac accctggaac ccagctataa
    98101 ctacaacctt accatcatct aaagctcttt ttaccttttt aggatttata tactttatct
    98161 ttgcattaga atattcatca cttgtaatta tacctgcttg ctgaccagta aagaaaacag
    98221 aatctatccc ctgtgcattc aataaattag caagaattgt tcctgatatt atttctccac
    98281 aagacattat taaatcaagt tctcttttac ttggctcatc atttactgca ctacacaaat
    98341 ttataagtgt atctgtagca tatggagctc cttttcttcc cattgctgaa actactaata
    98401 ctaattgtaa ttcttcatca ttttttttgt atgcttttac tatcttacat acttcattca
    98461 ttttttcata tgattctact gatgtcccac caaacttttg cactaaaata ctcatttttt
    98521 cctcctaaat atatccctca tattctataa ttatcatgtc attacctatt ttttttacat
    98581 ttctccatgg tacttctaaa aatgacttat cttttcttct ggcaaaaaat cctttttctt
    98641 ttggaattag aagcgctaat atatcgcctg tagtttcatc tagtataagg tcacattctc
    98701 caatgacccc caatctttct cctgtgacca agttaactat ttccttacct gctatttcag
    98761 ataaattcat attttatacc tccagagatt tacttttttc aatattaatc caagtgtaga
    98821 atcttttcta catctcttcc aactatacat gtaccaatat tttcgatatt gaatacctta
    98881 tcaacaacct tctttattga attaatatta acattattta tacattcaag tatttcatct
    98941 gtagttttta cttttttgct aagtaacata gatttaccag tagacatcat tctactgcta
    99001 gtactttcta aatccaatat ataatttcct tttaactgtt ccttgctttc agatatttct
    99061 ttttctgtaa gatagttttc tcttatattt tcaatttctt tctttattaa attatataca
    99121 tcttgtaaat tttctgtact catgcttgca aatataccta attcaccaca tttcctatat
    99181 aatgtctgtg atgagtatat tgaatatact aaaccttttt cttcccttat tttctgaaaa
    99241 agccttgagc ttatacttcc accgaaaata ttatttacca ctgccattga atagacttct
    99301 tcatcatttt caaaaggaat accttttagg cacatagcta agttcacctg ttcagtatct
    99361 ttattttttg atataaagca aggattaaac ttagcctcac ttatgtctat acttaaattt
    99421 ttcttttccc agtgtccaaa ttttgatttg attttctcca ccatatcatc aaagttaaag
    99481 tttccagcta tagaaataac agcgttattt ggaatataat acttatttaa gtattctaac
    99541 atggattctc tagttatatt gtacagagat tcttttgtcc caattatatt cattcctaat
    99601 ccatcattag catatatatt ttccactaat aaatcataag ataagtcatc tggagagtct
    99661 tcatacatct taagttcttc caatattata agtctttcct tatctatatc atttttatca
    99721 aatttagaat ttagtatcat atcactcaat acatcaattc ctgtatctat atgctcatct
    99781 attagtttta cataataaca tgtacattct ttacttgtaa atgcatttat ttgaccaccc
    99841 aaattatcta ttgaactagc aatctctttt gatgttctgt ttttggttcc tttaaacatc
    99901 atatgctcta taaaatgaga aattccactc acctgtgctt cttctatcct agagcctgca
    99961 tttatccaaa tacctaatgt tattgacttt agatatggta tttcttcacc aattattgta
   100021 agcccatttt ccagtatttt tgtcttatac attacattct cctaacaatt tattctttgt
   100081 ttcatattgg attattgaaa acactatgtt ttaattatat ttatttttta tatgtattac
   100141 attataagtc agtcttttaa ttaattcaac tacaacttat acaatcttaa ccaaatattt
   100201 atactttgtc tacttaaata catcactaag ttttcctggt tttagtcctt tttctcttac
   100261 aatagctata atatcatcta tacattttgt cgttgcgttg gttggatgca ttaaaattat
   100321 actactatct ttaatgtctt ttttcttcat tctatcaatg attacctctg gttggtcttt
   100381 gtatttccaa tctatagtat cggcatccca tttgatagaa gtatacccta atgctttagc
   100441 agcctttact gtttctggac caaaagaacc tgctggtgct tgaaaaaatt tagttttttc
   100501 acctataatt tcttcaatta tctttttaga ggtctctatt tgctcataat tgtcttcata
   100561 tgataatgta gaataatcta aatgtttgta tccatgatta cctatttcat gtccttgttt
   100621 ttttatcttt aataattcat ccttattctt ttctgcccat tttccagtta cattaaatgt
   100681 aatctttaca ttttcttttt taagtgtttc taaaatggat tctacgtact ctgtttccca
   100741 tccaaggtct atattacagg ttaatgcaac atatccactt ttatcctttg tacctctttc
   100801 atatggtaaa tctacaccat taaataaatt aaatactggc ttgttgttaa ataactttaa
   100861 taccattacc cctcctgata atactaataa cactactaaa attagtatta tgattttttt
   100921 gagcttactc ttattaagta ccatcattat cattaaaact ccccctaatt atgtacaaat
   100981 tgtttcttat ttaatactat taaaaataag ctctgtttat gcactaaata taacttaagt
   101041 gattctatat atatcaataa agctctctat taatcagctt ttaaatagct tctttataag
   101101 agtaaagcct gacagaaaaa gaactataag ccatccataa ctatcatttt aaaattatct
   101161 acttttttgt atttaaaaaa gcaaaatcct aagactttgc ttttaattat ataataagtt
   101221 atttattttt atgttctggt tttggtaaaa gaacttttct tgataaatta actcttcctt
   101281 tttcatcaat ctctgtaact ttaacttcaa cttcatcccc tatattcaat acatcttcaa
   101341 ctttggcaac tctttcatga gctatatgag atatatgaag taatccttct tttcctggaa
   101401 gtatctcaac aaatgctcca aagttcatta ttctacttac cttaccttta taagtttttc
   101461 ctacttctgg ttcaactact atattattta taagttcttg agctttctta atcatatcaa
   101521 tctcaatacc tgatataaat acttccccag tttgttcaat atctatctta actccagttt
   101581 cgtctattat cttagttatt atctttccac caggtcctat tacatctttt atcttgtcag
   101641 gatttatttg cattttaaca atcttaggtg catatggtga aagttctggt tttggctgag
   101701 atatagtttt tctcatctct cctagtatat ggattctacc ctctttagct tgttttaaag
   101761 cacgttgtag aatttcttta tctataccat caatttttat atccatttgt attgctgtta
   101821 taccatactc tgttccagct actttaaagt ccatatcgcc taaatggtct tccatacctt
   101881 gtatatctga aagcactgca accttaccat catgctttat aagtcccatt gctatacctg
   101941 caaccatatc ttttataggt acacctgcat caagtaaaga taatgttgag ccacatacac
   102001 ttgcttgaga tgtagaacca tttgaactta atacttcaga aactaatcta atagcataag
   102061 gaaattcttc ttgagatggt attactggta ataaagctct ttctgctaaa gcaccatgtc
   102121 ctatttctct tcttcctggt cctcttgatg gtctagcttc tccaacacta tatgcaggga
   102181 aattataatg atgcatatat ctcttgtttt cttcttcatc taacccatct agtttttgaa
   102241 catctcctaa agcacctaaa gtagcaacat taagtacttg agtttgtcct ctagtaaata
   102301 tggctgaacc atgagctcta ggtatcatgc cagtttcaca ccatataggt cttatttctt
   102361 caagttttct attatctggt cttacatttt catgtactat aagttttctt acttcttctt
   102421 ttattatatc ttgtaatact tcttctatat ctccaacaaa atcttcaaaa tcttctaaag
   102481 tttcttcaaa gtgagctaaa gtttcttctt taactctatc catattttcc attctctcta
   102541 acttttcaaa agtctgaact gcttttttca tcttatcagt tgcaaattcg cgaaccaatt
   102601 gagttatttc ttctcctgca tggtataatt caacaggcat tttttctttt ccaacttctg
   102661 caactatacc ttctataaac tcaactattt tttttatttc ttggtgagca aataaaatag
   102721 catcaagcat tacctcgtct ggaacttcat cagctccggc ttcaaccatc attattgctt
   102781 cctttgtacc tgaaacaact agatgcattg aacttttttc tctttgctct gcgtttggat
   102841 ttacaacaaa tgcaccatct acaaggccaa cacatactga acctgttggt ccattaaatg
   102901 gtatgtctga tatagaaagg gctattgaag aacctatcat tgctactata tctggtgtac
   102961 aatcttggtc tactgataga actgttgcaa ctacctgaac atcatttcta aatccttttg
   103021 ggaataaagg tcttattggt ctatctatca atcttgatgt aagtatagct ttctctgaag
   103081 gcttgccttc tctctttaaa aaacctccag gtatcttacc tacagagtat aatttttctt
   103141 cataatccac acttaaagga aaaaagtcta ttccgtctct aggtttggct gatttagttg
   103201 tatttaccat taccatacta tcactgtatc gaactataca actaccacta gccatttcac
   103261 aaatctttcc tatttctaca gaaagttctc ttcctgcaaa atccatttta aatattttat
   103321 gttcaaacat taatgcttgt cctcctctta ttaaaaaaca cgtatatcac tctatttact
   103381 atattatcaa aaatactata aattaacaat ataaaattat cttcacatat atatgcaaaa
   103441 accttatatt actactaatt agaacaactt atagccaata tatctggccc tgtatgagag
   103501 caaatagaaa ctcctcctcg agtaaataat actcttcttg cttttattct tttatttact
   103561 tcatctttta atatttcaca atcgtgtaaa ttatctccac aacctattgt gacgattttt
   103621 ccttctaaag acccttcatt catttctaaa attatatcga ccaatttact tgctatattc
   103681 tttattcctc taaccttatt taccaactta gcttccccat tatcaaagaa aaatataggc
   103741 tttatattta acatatttcc tatcaaagca gttgcaactg gaactcttcc actctgcttt
   103801 aaaaaatcaa gtgtatatgg tgcaaaaagc aatcttacac tactgcgagt attttctaat
   103861 tcatctataa tttcttcaaa tcccagtcct tcttcaagaa gttcacatgc ctttataaca
   103921 tattgtccac tacctagaga taaatttcta gtatcaaata tatgtatttt ttcattttca
   103981 tttacatcat ttttagctat catagcactt tgaaaagttc ctgatgcgtt tgcagcccct
   104041 gtcatacaga ttatatgata accttctgtt atgaacttat caaacacttc tttaaactcc
   104101 atatatgtag cttgtgaagt tttaggtatt tgcttgattt cttttacttt tttataaaac
   104161 tcttctttct ttatatctac tccttctata tattccctat cattaaaaat aactgtaagt
   104221 ggaactatct ctatataatc tttttctgat atttcatctg gaatatcgca caaactatcg
   104281 catactaact ttattttcaa aataatatcc tccttattcc aactaattat cctgttataa
   104341 aatttctata tttatcctgt ctttcctttt aaattgatta tgtatttgta tactatttta
   104401 atattcttac ccaatattat tcattttata attttttata acatataaac tacttttatt
   104461 attaactatt ttactttata atgaattaac tataaaaaag caggtataca ctatacctgc
   104521 ttttttataa agaatgaaat tactttctta atcctaattt agctattaat gctctatatc
   104581 cttcaagatc tttttccttt aagtaagcta ataagtttct tcttctacca accattttta
   104641 atagtcctct tcttgaatgg tggtctttct tatgagtttt taaatgtcca tttaactcgt
   104701 ttattctagc tgttaataaa gctatttgta cttctggaga accagtatcc ccttcagctc
   104761 ttccatattc ttttattatt tctgatttgt ttatcattta gattacctcc gtattttttt
   104821 agaaacgcct attactaagc attgattgga gtattcaaat gctgagtaat ggttattttc
   104881 cttaatcatt ttatcataca ttacttgttt ttgcaaacat agttttcata cacataattt
   104941 gtatcattat acaattgatt ttttaagtca tctattgaat taaactttct ttcatctctt
   105001 attctttcca aaaattcaac aattatattt tccccataaa tatctctatc aaactctaaa
   105061 atatttgttt caatagacaa agtttttcca ttaactgttg ggttatagcc tacatttgta
   105121 gcaccaaaat aagtctcatc tccaatatgt acaatagaag cataaatacc tctctttgga
   105181 acgagcatat tattcttaag gtcaatattt gccgttggga atcctatagt tcttccaagg
   105241 tgtttagaat gtataacaca accttctaac ttgtaatttc tacccaaata ttccttgaca
   105301 ttagccatat caccctggga tactaaactt ctaatataag tactactcac tcttacatca
   105361 ttgattttga tgggttttat tacttctacc tcaaaaccaa attcatgttc taagcttttt
   105421 aatagattaa cattgccttc ttttgccctt gcaaatgtaa agtcatgtcc aattactatc
   105481 tttttagctt ttaatttttt tactagtatc tcatctacga aatcctttgc aggtatttta
   105541 gtcatatact catcaaatgg tatgattaca actatatcta ttcccaaatc ttctaataat
   105601 tttattttat catcattgct tataatattt tttgttgagt ttggtctaaa gtaatttaca
   105661 ggatgatttg caaatgtaaa tacgatactc tgtatatttt ctttttttgc atgttcaact
   105721 gtttttccta taagaacttg atgtcctttg tgtacaccat caaaatttcc tatggtaatg
   105781 acactttctt ttatgtttgc tatttctttt atagatttta taatcaccat aataaatgtt
   105841 ccccgctaaa atataattta ctcttaactt attcacaaac tattatagca taagtaaaag
   105901 agatagacta tagaagttat tatagtacta tctcttttgt tgttttttta aatacattgg
   105961 ttatatgaac atcttatcac ttttaacact tattgtatta ttgtgttttg ataattttcc
   106021 taatcctaag aaattatctg tactgtatac tcttacaaat tcatcatctt tatcgaaatt
   106081 attttttaaa aaccttttat catctattga gccaccatta ctataatatt ttatagcatt
   106141 agggtttaat acaacataat taaacgaatc aaggacataa tctatatcat ataagtattt
   106201 gtctaaagtt ttattttcat aaaataattc taattcttct aatgttattg aattatctaa
   106261 gtcaaattta ccagaagatg ttctattcaa aaacgacata tgagctccac aacctagata
   106321 ttctcctata tcatggcaaa tgcttctcac ataagtccct ttagaacact caacataaaa
   106381 cattacttta ttacctttta tacttagtat ttttatgtct tttatattta ctcttcttgt
   106441 ttttaaagta atttcagatt gtctaccact tcttactaaa tcacacattc tctttccatt
   106501 tacctttaaa gctgaataaa ttggaggaag ttgatttatc tctcctcttt gtgtgtcaaa
   106561 agctctttct atgtcttcat tactaaattt aaaatcatca acttttttta aaatttcacc
   106621 tgaagcatca taagtatctg tacttatacc taaagtaagc tcacatatat acgatttatc
   106681 tttgtttaaa ataacttcac atacttttgt agctttccct atacagattg gtaaaacacc
   106741 tgaagcatct gggtcaagag tacctgtatg accaactttt tttatattta aaatctttct
   106801 cactctactt acaacatcat gagatgtcat acctgtgggt ttcaatatac ttataatctt
   106861 attcatttta ctgtcacctt aaattgattt taacactgcc tctagtacca ttttctttgc
   106921 attatcaata ctatctctaa tagtacatcc agcagccctt acatgaccac caccaccaaa
   106981 taacttggct atttcactta catcaacata attttttgac ctaaaactca ctttaatttc
   107041 attttgtttt ttctctttaa ataaaattcc aacttctata ccttttatgt ctcttgtata
   107101 tgttgttatt ccatcaacat cattaaagct aatattattt ctattcatca tgtcttgagt
   107161 taaaactata ctagatacct ttgactgaac ctcccatgac taaagtcaca gggttcctgc
   107221 ttcacagaat tttgcatatt aaaatatgtc ttactaattc tccacaggct atccccgtag
   107281 ttcctacggt tcttacataa gttatttatt ttgaatcgtt attagtctta atccttcttt
   107341 taatatattt atacttgcat ttatatctct atcgtgagtt tcattacaac taggacaaat
   107401 ccattctctt atatttaaat ccttaacttc ctcgttttta tacccacatt tattgcatat
   107461 ttgtgaactt gcaaagaatt tacctacctt tacaattttt ctaccatacc aattagcctt
   107521 gtattctaat tgacgaataa attctgacca tgatacatct gaaattaagc gagatagttt
   107581 acgatttcta atcatattct ttacttgtaa atcttctatg caaataatat cattctcttt
   107641 tattaattta gtagatagtt tttgtagaaa atcatttctt tgattagcta tatgttcttg
   107701 aagtcctgca acttttaatc ttgctttatt tctatttaaa ctaccgattg tttttctcga
   107761 taattctctt tgtaatttag caagcttgtt taatgacttc ttaagatact taggattttc
   107821 tataaagtct ccacaacttg agatacaaaa ttctttaatt cctaaatcta aacctatatg
   107881 attattagta tt
//
LOCUS       DAEPHU010000003        98774 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 01A10CD0081
            SAMN05941466-rid12468953.denovo.003, whole genome shotgun sequence.
ACCESSION   DAEPHU010000003 DAEPHU010000000
VERSION     DAEPHU010000003.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941466
            Sequence Read Archive: SRR6291087
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 98774)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 98774)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068158.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 22:43:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,892
            CDSs (total)                      :: 3,805
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 87
            rRNAs                             :: 8, 1, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 55
            CDSs (without protein)            :: 55
            Pseudo Genes (ambiguous residues) :: 0 of 55
            Pseudo Genes (frameshifted)       :: 21 of 55
            Pseudo Genes (incomplete)         :: 28 of 55
            Pseudo Genes (internal stop)      :: 16 of 55
            Pseudo Genes (multiple problems)  :: 8 of 55
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..98774
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941466-rid12468953.denovo.003"
                     /strain="01A10CD0081"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            88..204
                     /gene="rrf"
                     /locus_tag="KR231_000193"
     rRNA            88..204
                     /gene="rrf"
                     /locus_tag="KR231_000193"
                     /product="5S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00001"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00001"
     gene            324..515
                     /locus_tag="KR231_000194"
     CDS             324..515
                     /locus_tag="KR231_000194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF378 domain-containing protein"
                     /protein_id="HBH0002612.1"
                     /translation="MKKVALILAIIGALNWGAIGILGTDLIGSIFGGTYEMVSRIIYF
                     IVGLAGLYLIPSLMSDDRE"
     gene            670..2079
                     /locus_tag="KR231_000195"
     CDS             670..2079
                     /locus_tag="KR231_000195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class I/II-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="HBH0002613.1"
                     /translation="MFIINELNKIVNEEVISFHMPGHKKGQVYKKLGYKDILKNLYKM
                     DTTEILGTDNLHFPEGIIKNSQKKASRVFKSDYTCYLVNGSSCGIQSAIMSVCSPKSK
                     IITNRDCHQSVINGCILGDIDIEYVPCEISEETNILKGISISNVIDIIDKNLDAKAVL
                     LTYPTYYGMTYDLEYICNYAHSKKMVVIVDEAHGAHLGLSERLPKTALEQGADIVVQS
                     THKTLPAFTQSSMIHIQGDRVDIDKILNMLRITESSSPSYLLLSSLELAVDIYENKGK
                     ELMEELLNNIITFKNKVDSNINIYDTNDKTKIFISSKNMGLTGYELENILRNKYNIQV
                     ELSNYYGVLLICTIGNTAEDFSSLETALNNVVKEDFKFEKLENKKYPVVIPKKILTPR
                     EAFYKTKKSVKIYDSIGKVCGECIVPYPPGISVISPGEVISKEIIDYLMFCHSKGMIV
                     SGLKDVDLNFIQVIDLEDI"
     gene            2210..2899
                     /locus_tag="KR231_000196"
     CDS             2210..2899
                     /locus_tag="KR231_000196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidylate kinase"
                     /protein_id="HBH0002614.1"
                     /translation="MKGKLIIIESGSDASGKATQTEILYERLKKEGYMIKKVEYPNYE
                     SPSSALVKMYLKGDFGKNASDVDPYIASTFFTADRYASFKTDWEEFYNEGGIIIADRY
                     TTSNMVHQASKMDICDREEYLNWLADYEFNLFKIPQPDCVIFLDVPIEFSKKLMENRK
                     NKITGEEKKDIHESDIEYLEKSYNNALYIADKYDWKKINCVLDNKLRSIESIHNEIYK
                     IVLDSIKPMER"
     gene            2902..3837
                     /locus_tag="KR231_000197"
     CDS             2902..3837
                     /locus_tag="KR231_000197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta'"
                     /protein_id="HBH0002615.1"
                     /translation="MYFENIIGQDFAKKYLTNSIKKNKLNNAYMFEGMDGIGKKKFAD
                     ELSKLLLDYENLENSPDYVLIKPDGNSIKIAQIRNLQSDIVIRPHKDYKIYIINNAEK
                     MTVEAQNALLKTLEEPPNYAIIILVTNNKESLLETIKSRCDIIKFSPIPIEDLKRYLI
                     NTGIEEERAQLLAIFSRGSIENALNLSQSSEFSMMREDIQQYIQIMLDKNIVEILNIP
                     NNMEKYRGKIIALLDMMINYFRDIILLKENVNKNMLINVDKLVFIQNMNGKISYSQLS
                     KIIDIIEDAKSKIKSNCNFNISIQVMSLNIYEVIK"
     gene            3834..4727
                     /locus_tag="KR231_000198"
     CDS             3834..4727
                     /locus_tag="KR231_000198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427637.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage 0 sporulation family protein"
                     /protein_id="HBH0002616.1"
                     /translation="MIKIVGIRFKSAGKIYYFDPVDFNIEQDMDVVVETARGLEYGKV
                     VVGPKDMDESELVSPLKPIIRIATEEDKKVYLENKEKAKETFELCQQKIKEHELTMFL
                     IDCEYTFDRNKLIFYFTAEGRIDFRELVKDLAAIFKTRIELRQIGVRDEAKSIGGLGP
                     CGRKLCCSSWLGDFQPVSIKMAKDQSLSLNPTKISGICGRLFCCLKYEHDVYSEAIEK
                     MPVVGALVQSDDGKGKVVEVNPLLEQIKVEFQDKTVKIYTREDIKILREPKKCDGCGG
                     KCKDNDGLDEATLRELKKLED"
     gene            4805..5551
                     /locus_tag="KR231_000199"
     CDS             4805..5551
                     /locus_tag="KR231_000199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA1(Val) (adenine(37)-N6)-methyltransferase"
                     /protein_id="HBH0002617.1"
                     /translation="MQLKDSERIDDLQLKGLKIIQDTNGFCFGIDAVLLANFTKIKKD
                     AKVVDLGTGTGIIPILIAGKSEAKKIIGVEIQEDVYEMATRSIKLNGLEERVEIINED
                     IKYIDKVLDINGYHVVTSNPPYMHIDGIKNPNDKKAISRHEVRCNLEDVIRAASRLVM
                     PRGKFFMIHRPTRLVDIITLGRKYKLEPKVIQFVHPRPQKAPNLVLVQFVKDGRPELK
                     ILDPLYVYGEDGNYTKELKAIYNNKDIGEL"
     gene            5552..6385
                     /gene="rsmI"
                     /locus_tag="KR231_000200"
     CDS             5552..6385
                     /gene="rsmI"
                     /locus_tag="KR231_000200"
                     /EC_number="2.1.1.198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (cytidine(1402)-2'-O)-methyltransferase"
                     /protein_id="HBH0002618.1"
                     /translation="MSGKLYICPTPIGNLEDITYRTLRILKEVDLIAAEDTRHSIKLL
                     NHFEISKPLTSYHEHNKDSKGDYLINKLIDGENIALISDAGMPGISDPGEEIIKQAIQ
                     NNIEIEVLPGATAFVTALVGSGMDTHRFIFEGFLDRDKKVRKAQLEELKEESRTIIFY
                     ESPHRLKDTLKDMLKILGNRNISINRELTKKYQEIIRENIETTIKIFEEKEVRGEFVL
                     IVEGFHGEKSKKENYDGLTDREYVLKLIESGMNKKDAIKIVCKDRKLKKDVVYKQVLD
                     L"
     gene            6408..7112
                     /locus_tag="KR231_000201"
     CDS             6408..7112
                     /locus_tag="KR231_000201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HDIG domain-containing protein"
                     /protein_id="HBH0002619.1"
                     /translation="MEIGKIIIESLKREDTHKIFIELDNKHELEKIIPKISCMKSVGE
                     CKYHVVNCFEHSINALKELEIVLNDKDFFPIHLRKHVSNYLKTYIEEGINKLHVLKLG
                     TFLHDIGKPDSMTLDETGRVHFTNHEKIGAQIIDNMGIKLELSTETYRLISKYVRYHM
                     ILLSLYKKNDLSRKELINVFNLVDEDTIGVIMLGYADIVSTVKLLGKSGEVSVLKTYM
                     EYILTNYLYKSNYTHV"
     gene            complement(7300..7728)
                     /locus_tag="KR231_000202"
     CDS             complement(7300..7728)
                     /locus_tag="KR231_000202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007287587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Lrp/AsnC family transcriptional regulator"
                     /protein_id="HBH0002620.1"
                     /translation="MDVTDYRIIEILQDDGRISMKDLGKIVGLTSPAVSERVKRLEES
                     GVIEGYKAIVNPDSLGRVIKAFIHISLPSNGYTEFIESAAKDPRIVECHHITGDDCLL
                     LKVIVKDMYELENVIDTIKKIGSTKTSVILSTPIQAKSIL"
     gene            complement(7765..9195)
                     /locus_tag="KR231_000203"
     CDS             complement(7765..9195)
                     /locus_tag="KR231_000203"
                     /EC_number="6.3.4.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate phosphoribosyltransferase"
                     /protein_id="HBH0002621.1"
                     /translation="MRNLTLLTDLYQLTMLNGYFEKNIHEDIVVFDMFFRKNACDGGY
                     TIVCGIDQVVEYIDNLHFSDEDLEYLKNLNLFSDKFLKFLKEFKFTGDIYAVEEGTIM
                     FPNEPLITVKAPLYQAQLIETALLTIVNFQSLIATKASRVCFAAQGDPVFEFGLRRAQ
                     GPDAGIYGARAAVVGGCAGTANVLAGKMFDIPIIGTQAHSWVQKFDNELEAFQAYADV
                     YPDKCLLLVDTYDVLNSGVPNAIKVFKNISEKGYKPMGIRLDSGDLAYLSKEAKKQLD
                     NAGFSDISITASNDLDEYTITSLKAEGATINSWGVGTKLITSFDSPSLGGVYKLAASC
                     EKGVLEPKIKISENPEKINNPGYKKVIRIYNEDNKAEADLIMLHDEVIDESKPLEIFH
                     PTYTWKTKVFTNYKVKELLKPLYIKGRCKYNKKAVLEIKNHVQYELSTIWEQYKRLSK
                     PHIYKVDLSRNLWYLKTQMIDSKKVL"
     gene            9327..9911
                     /locus_tag="KR231_000204"
     CDS             9327..9911
                     /locus_tag="KR231_000204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="spore maturation protein A"
                     /protein_id="HBH0002622.1"
                     /translation="MIIIGKIWFYMVSIGIIGSLISKNMGELNKVILSETSKGIEFAI
                     SLAGIMALWMGIMNIAKESGLIEKIGQKLNPIMRRLFPSIPKGHKAMSYIVMNIALNM
                     LGAGNGATAFGLKAMSELQTLNNKKDTATNDMIMFMVINISSIQIIPFTIIKLRMDMG
                     AQNPSEIIFTTLFATIISTAVAIITCKFFQRRYR"
     gene            9927..10448
                     /locus_tag="KR231_000205"
     CDS             9927..10448
                     /locus_tag="KR231_000205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="spore maturation protein"
                     /protein_id="HBH0002623.1"
                     /translation="MEIFSNLLIPIIILYIVVYGKYKKIDVYDSFVKGAIDGLKAAWD
                     ILPYIIGIFLAIGIFKTGKGLDMLEWLFTPIANMMSIPKELIGLISVKPLSGSGALGM
                     YSELANRVGIGSLVEKMGATIVGSSETIFYTMAIYYGSLKIKNTRHTLSCAMISHVAG
                     VIAAVFICYVIFV"
     misc_binding    10514..10760
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            10844..12781
                     /gene="metG"
                     /locus_tag="KR231_000206"
     CDS             10844..12781
                     /gene="metG"
                     /locus_tag="KR231_000206"
                     /EC_number="6.1.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine--tRNA ligase"
                     /protein_id="HBH0002624.1"
                     /translation="MSKPSFYVTTPIYYPSGGLHIGHTYSTVAADTIARFKRFCGYDV
                     KFLTGTDEHGEKIQKKAIEQGMSEIEYLDGMIKDIKALWNTMDISYDDFIRTTEKRHT
                     DIIQKIFTKLYEQGDIYKGEYEGRYCTPCESFWTESQLLEGNKCPDCGRETYLVKEES
                     YFFRLSKYEDRLKELFKDDSFCFPAARKNEMVANFLDKGLEDLSVTRTTFDWGIKVPF
                     DEKHVIYVWVDALCNYITALGYMTDNDEEFKKYWPANVQIVGKEIVRFHTIIWPALLM
                     ALGLEVPKQVFGHGWILFADDKMSKSKGNVVYPEPIIERYGIDTLKYFLLREFAFGQD
                     GSYTHRNFVTRINYDLANDLGNLISRTVAMVEKYNNGIIPTAKVSTNFDADLKEQAVS
                     TRENFEAEMDKMQFHEALESVWKLVRRTNKYIDETMPWALAKDETKKDELDTVLYNLC
                     ESIRIIATLINPIMNETANKIYEHIGIKGQDDITTWESTKTFGLIGENVKVFKGEPLF
                     PRLDVEKEIEELTKMFSGKPPVEEKPLEHKEEITIDDLDKIELRVGKIISCEKHPKAN
                     KLLVSQVKIGPETRQIVSGIAEYYKPEDLVGKEVTVVCNLKPVKLRGVESQGMILAAG
                     DDGDPYVLPFTQGAKDGCEVR"
     gene            12811..13581
                     /locus_tag="KR231_000207"
     CDS             12811..13581
                     /locus_tag="KR231_000207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TatD family hydrolase"
                     /protein_id="HBH0002625.1"
                     /translation="MLFDSHAHLNDESFDEDRDELIGSLKDKGVDLVVNPGADIETSI
                     TAIELAKKYDFIYSAVGVHPHDVSKLDDTAIETLRKLATENEKVVAIGEIGLDYYYDY
                     SPREEQKEWFKKQIELANELKLPIIIHDRDAHGDTFEIIKNTKNPEIGCVLHCYSGNV
                     ELAREYVKMGCYISIPGTVTFKNNKKTREVVREIPLERLFIETDSPYMSPEPHRGKRN
                     NPSQVSFVADKIAQEKGISYEEVCRVTKENAKKFFNIK"
     gene            13918..14349
                     /gene="phnG"
                     /locus_tag="KR231_000208"
     CDS             13918..14349
                     /gene="phnG"
                     /locus_tag="KR231_000208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphonate C-P lyase system protein PhnG"
                     /protein_id="HBH0002626.1"
                     /translation="MYTVDSTKILINMNLEKLEKIYSMIKDTSSISIIKEPNLATVMV
                     RANESVKNTTFNLGEILVTECSVKVDESLGYGIVSENNNKKAIYLAVIDAVLHSNNSK
                     FDELKNYINKSVYEENLRYEQEIIDEFSLINKTKVQFNAMD"
     gene            14364..14939
                     /gene="phnH"
                     /locus_tag="KR231_000209"
     CDS             14364..14939
                     /gene="phnH"
                     /locus_tag="KR231_000209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphonate C-P lyase system protein PhnH"
                     /protein_id="HBH0002627.1"
                     /translation="MVNYTQEIYRKMLDSASFPGKLNNIDNINIENNTKLLNGAIGIA
                     ITLLDQEVTFYIENYTQKDIKNIRALTMSNQIDYRKSDYIFLDINSEVDILQIKIGSF
                     EYPDESATIVHQVNDLSTYSQTKYIKLDLSGPGIKSKNSIYINGIREEFIERLSSINK
                     DYPIGIDLILVDKKGEIAFIPRSSKLSWEVL"
     gene            14942..16027
                     /locus_tag="KR231_000210"
     CDS             14942..16027
                     /locus_tag="KR231_000210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbon-phosphorus lyase complex subunit PhnI"
                     /protein_id="HBH0002628.1"
                     /translation="MAYVAVKGGEEAILQAKNILEFYRVKGDSLPIDVKQIEEQMSYA
                     VDKVMSEGSLYNKELSALAIKQAQGDILEASFYVRALRSTMPRITYSEPINTEEMRIK
                     RRISATFKDIPGGQYLGATRDYENRILNVELLEEDEKKNRHFRDSFINELETVDEIPE
                     FTKISNIFRKENLLQEEVCENKLEEVIDDITRNSLRFPVSRSAKLQALTRGESGVVSG
                     FAYAIVRGFGDEHPYISELRTGNVFIKVKHPIYEDEEIIIGDMLVTECEIVSKASQNK
                     TENSKTNSEDKNKMSLGYGLCMGNNENKAISMAILDKSLEPNSEKLAQDEEFVLLHID
                     GIDSLGFISHFKLPHYVDFKADVERIK"
     gene            16047..16916
                     /locus_tag="KR231_000211"
     CDS             16047..16916
                     /locus_tag="KR231_000211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-D-ribose 1-methylphosphonate 5-phosphate
                     C-P-lyase PhnJ"
                     /protein_id="HBH0002629.1"
                     /translation="MIYNYGFLDENTKKEIRRKILKAISIPGYQVPFGSRELPIAKGW
                     GTGGLQLTLSLIGKNDVVKVIDQGSDDSTNACNIRSFIASVSNVETTKDTLEATLIQT
                     RHRIPEEKLKSNQILIFQVPIPETLRIVEPSEVETRRMHSEEDYSRMWVYLYEDIVRF
                     NDISIAVEYPCKVNDRYLMNPSPIPRFDIKKLNMSDNLFLFGAGREKRIYAIPPYTKV
                     EPLEFEDYKFEEEKFEGKYCSLCNSTNTFLDEVYDSDTNEKYYSCSDTSYCEKVRLKN
                     NSIDVTIGGTWNE"
     gene            16909..17775
                     /locus_tag="KR231_000212"
     CDS             16909..17775
                     /locus_tag="KR231_000212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBH0002630.1"
                     /translation="MSKINDSKRLENIDKQVLIGRNINLIYGDGCEKCFESTGYESNN
                     ICKYCGSIVACNNVNLELYEGEVLGIVGESGSGKSTLLKILFFQEHANSGEVYISHYN
                     KDTNILELSDQKKRYIKNHFMGIVYQNPHLGLNLDFSSGGNIAEKLLMANLYNVEKIR
                     DRGKELLIKTNIPVERIDHKPKYFSGGMQQRVQIAKALSNNPPILLLDEVTTGLDVSV
                     QAEVLDLIREIQRELKISMIVVSHDFDVIKMLADRTIVMKNGSVIESGLTDQIMEDPQ
                     HPYTQQLINSLL"
     gene            17816..18529
                     /locus_tag="KR231_000213"
     CDS             17816..18529
                     /locus_tag="KR231_000213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBH0002631.1"
                     /translation="MKETILEVNNFSKDFELHALNKTITACSNISFEVSKGEFLGIIG
                     KSGAGKSTILKSIYKTYIPTTGEIIFNSEIYGNVDLAKIGDREMINLRKKEIGYVSQF
                     LKTLPRITAIELVVHSLIESGFEKDCSYDMAKDILNQFEIKENLWDAYPNNFSGGEKL
                     RLNLAQAMVKKPRLLLLDEPTASLDNQSKIYVKEKMLELKSQGTTMIGIFHDIEFMET
                     VIDKTFTMTKGTISESGVA"
     gene            18530..19699
                     /locus_tag="KR231_000214"
     CDS             18530..19699
                     /locus_tag="KR231_000214"
                     /EC_number="3.6.1.63"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-D-ribose 1-methylphosphonate
                     5-triphosphate diphosphatase"
                     /protein_id="HBH0002632.1"
                     /translation="MIKLIHNANIVLEDMILENGHLIIEGDTIKKVSNDKIDYAFDFN
                     EIDEIIDAKNLYVIPGIIDIHSDAIEKEIEPRPSTLLPFNMAFYELDKKLPANGITTV
                     YHSISLGDGVGVRSIDNSLKMIKNIDSYKNIDSKSINHKVHLRYEVLYYEGLEKVLEL
                     LDENKIDYLSIMDHSPGQGQYTNPTFYKEYATKVWGVTENYVDTWLDDLVNLHDNLDW
                     NKIANIIGIAKTKNINVASHDDDTLEKMDFIKNIGINVSEFPITLEVAKHSKKLGVLT
                     CLGAPNIVRGKSHNNNLKAMDAILEDCCDIVCSDYLPSAMIKSMCIVAERINNLNKAV
                     SLFTSNPAKAVGIYDERGSIKENKKADLVLVDIDSEYPKVVNTIVNGKTVYKREV"
     gene            19703..20539
                     /locus_tag="KR231_000215"
     CDS             19703..20539
                     /locus_tag="KR231_000215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PHP domain-containing protein"
                     /protein_id="HBH0002633.1"
                     /translation="MLTELHCHTSISDNNFTTEEIIKKAAEKNINILAITNHDTLSGL
                     DEALVLGEHYGITIIPGIEISAYDYKNRKRVHILGYNIDLNSQEIKNLCNPMVCDRHK
                     ASVKMVNKIIDLGYKISLEDVKKYSSKTGIFKQHIMKALIDKGYTDNIYSNLYKELFH
                     RGNGKVYVSLKYVDYRDAIKAIKNSGGICVLAHPGQMDNFSAIEEMVKVGLDGIEVYH
                     PSHNKELEKESLSYAKKYNLVVTGGSDYHGFYSQHNYELGSKSLNKEDLFKFRLALGG
                     VL"
     gene            20540..21535
                     /locus_tag="KR231_000216"
     CDS             20540..21535
                     /locus_tag="KR231_000216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861991.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBH0002634.1"
                     /translation="MSFLQVKNVGKSYGQVKVLKDISIDIEKGEFICLLGPSGCGKST
                     LLRIIAGLEDKHGGKIIINDKDMTNSPPESRNFGIVFQSYALFPNMNVYKNIAFGLEN
                     KNISKSNIDKKVKEVLEVVELSGYEKKYPSQLSGGQQQRVALARAIALEPDFLLLDEP
                     LSALDAKVRLKLREQIRSLHRKLGITTIMVTHDQEEALCLADKMVVMNRGEIIQVGTP
                     KEVYKNPETPFVADFIGTINFIDDGINKIAIRPEDIKVESNRDSKDKDIKVGEILDIE
                     FRGFNYRITVEYRSKQMKLDVVSKVAEQMKLCIGSKINFKIPKEGIVQYKSEGCA"
     gene            21553..23241
                     /locus_tag="KR231_000217"
     CDS             21553..23241
                     /locus_tag="KR231_000217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894042.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative 2-aminoethylphosphonate ABC transporter
                     permease subunit"
                     /protein_id="HBH0002635.1"
                     /translation="MITSKNKRRISDSTIQKYFLIFSVIVLIVFILFPLVSLLKNAFM
                     DTSGNFIGISNFSKYVENPSLIASFKNSIFVSTVSSLISLCLAFIYSYAITRTNIKFK
                     DFFKTMGMFPLFAPTMLYGISLIYLFGNKGIFTTMGLEVPLYGPLGIIISQILFTFPQ
                     AFLILSVALSMADYRLYEAADSLGASEFKKFCKITIPGIKYSLLSSFFVSFILAFTDF
                     GAAKVVGGNYNVLATDIYKQVVGQFNIPMGATVSMVMLIPVLIAFTLDKMASKKQGMT
                     ITAKSMPYKIKENKFRDRVFLIVCSFITLLIFILIFVSVIGSVIKLWPYNLSFTMEHY
                     TFKGILGSGIKTYLSSLKISTLTAIFGTIFVFFSAYMIEKVDKFPKLRQTAYLLSMIP
                     MALPGLVLGISYITFFNSASNPLNFLYGSTAILVIVNVVHFYSVCFITSNSSLKMLDK
                     EYELVAKSINIPFYKVFFNITVPMSITSILEIVVYYFVNSMVTVSALIFLYTPQTQTA
                     SISILKLDEIGYIGTSAAMAVLVLLTNIIVRLLYEFVTKKLKNNTQKWQQKDVA"
     gene            23253..24320
                     /locus_tag="KR231_000218"
     CDS             23253..24320
                     /locus_tag="KR231_000218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative 2-aminoethylphosphonate ABC transporter
                     substrate-binding protein"
                     /protein_id="HBH0002636.1"
                     /translation="MKFKKLVSLGVLSTLLLSVITGCSTDSSGSDSKSDSKTKGDLTV
                     YTAIEEDSIEPYLATFKEKYPDIKLNIVRASTGDITARLLAEKDNPQADVVWGVAATS
                     LLVADDQGMLEPYAPKGSEEIESAFKDDKEVPSWVGIDAWMTGITVNTKELSDKNIPV
                     PSSYEDLIKPEYKGLISMPNPSSSGTGYLTVSALIQIMGEEKAWQYMDKLHENIGVYT
                     QSGSAPATSAASGEYPIGISFGYRGIKLKEEGYPVEVVFPKEGSGWDIEANALVKKDN
                     IKEASKVFLDWAISKDVMNEYSKNYAVTTISTGNPIPEGFPKKPLEQMIDNDLKSAAK
                     NREDILNKWISKYDGKTEKES"
     gene            24757..25752
                     /locus_tag="KR231_000219"
     CDS             24757..25752
                     /locus_tag="KR231_000219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861991.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBH0002637.1"
                     /translation="MSFLQVKNVGKSYGQVKVLKDISIDIEKGEFICLLGPSGCGKST
                     LLRIIAGLEDKHDGKIIINDKDMTNSPPESRNFGIVFQSYALFPNMNVYKNIAFGLEN
                     KNISKSDIDKKVRDILEVVELSGYDKKYPSQLSGGQQQRVALARAIALEPDFLLLDEP
                     LSALDAKVRLKLREQIKSLHRKLGITTIMVTHDQEEALCLADKMVVMNNGEVIQIGTP
                     KEVYKSPKTPFVADFIGTINFIDDDVNMIAIRPEDIKVEFNRDFKEIDVKVGEILDIE
                     FRGFNYRITVEYCSKQIKLDVVSKVVEQMKLCVGSKINFKIPKERTIQYKSEGCA"
     gene            25770..27458
                     /locus_tag="KR231_000220"
     CDS             25770..27458
                     /locus_tag="KR231_000220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894042.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative 2-aminoethylphosphonate ABC transporter
                     permease subunit"
                     /protein_id="HBH0002638.1"
                     /translation="MITIKNKRRISDSKIQKCFLVFLVIALVVFILFPLISLLKNAFM
                     DTSGSFVGISNFSKYIENPTLIASFKNSIFVSTISSLISLCLAFIYSYAITRTNIRFK
                     NFFKTMGIFPLFAPAMLYGISLIYLFGNKGIFTIIGIEVPLYGPLGIIICQILFTFPQ
                     AFLILSVALSMADYRLYEAADSLGASEFKKFFKITIPGIKYSLVSSFFVSFILAFTDF
                     GAAKIVGGNYNVLATDIYKQVVGQFNIPMGATVSMVMLIPVLIAFTVDKIASKKQGMT
                     ITAKSMPYKIKENKFRDRVFLIACSFITLLIFILIFVSVIGSVIKLWPYDLSFTMEHY
                     TFKGISGNGIKTYLSSLKISILTAIFGTIFVFFSAYMIEKVDKFPRLRQISYFLSMIP
                     MALPGLALGISYITFFNSASNPLNFLYGSTTIMVIANIVHFYSVCFITSNSSLKMLDR
                     EYELVAKSINIPFYKVFFYVTLPMSITSILEVAVYYFVNSMVTVSALIFLYIPQTQTA
                     SISILKLEEIGYIGPSAAMAVLVFLTNIIVKLLYELTTKKLKTKTQKWQQKEVA"
     gene            27470..28537
                     /locus_tag="KR231_000221"
     CDS             27470..28537
                     /locus_tag="KR231_000221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative 2-aminoethylphosphonate ABC transporter
                     substrate-binding protein"
                     /protein_id="HBH0002639.1"
                     /translation="MKFRKLVSLGILSTLLLSVITGCNNASSGSNLKSNNKIKGELTV
                     YTAIEEDSIDTYLTTFKEKYPDIKLNVLRLSVGDITARLLAEKDNPKADVLWGVAATS
                     LIILDDKEMLEPYAPKGFDKVNPVFKDDKKVPSWVGIDAWMTGITVNTKELSDKNIPV
                     PSSYEDLIKPEYKGLISMPNPASSGTGYLTVSELIQIMGEEKAWQYMDKLHKNIGVYT
                     QSGSAPAILAASGEYPIGISFGNRGIKLKGEGYPVEVVFPKEGSGWEIESNALVKKDN
                     IKEASKVFLDWAISKDAMNEYSKNFAVTTIDTGNPVPEGFPKNPLEQMIDNDLKSAAR
                     NREAILNKWIEKYDGKTEKES"
     gene            28729..29259
                     /gene="rnmV"
                     /locus_tag="KR231_000222"
     CDS             28729..29259
                     /gene="rnmV"
                     /locus_tag="KR231_000222"
                     /EC_number="3.1.26.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease M5"
                     /protein_id="HBH0002640.1"
                     /translation="MIKEIIVVEGRDDVTAVKRAIDAELITTGGFGFPKGVMERIKAA
                     NERRGVIIFTDPDFAGEKIRKKIASEVPGCKHAFLPREEAKKDGDIGIENATPQSIIA
                     ALNKVRTENTEKRDEFKQVDLIRNGLIGNEEASLRRDALGKILGIGYGNAKQFLNRLN
                     NYGVEREEFIDALKQI"
     gene            29430..30299
                     /gene="rsmA"
                     /locus_tag="KR231_000223"
     CDS             29430..30299
                     /gene="rsmA"
                     /locus_tag="KR231_000223"
                     /EC_number="2.1.1.182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (adenine(1518)-N(6)/adenine(1519)-N(6))-
                     dimethyltransferase RsmA"
                     /protein_id="HBH0002641.1"
                     /translation="MDRLSSHNATKEVVQKYNFKFSKSLGQNFLIDSNIIDKILSGAR
                     ITRGDNIIEVGPGIGTLTREMGKIAEKVVAIEIDRNLIPILKDTLSDLDNTEVVNQDI
                     LKVDIQELVKDKLNGGPVKLVANLPYYITTPIVMKFLEEDIPVTDIVVMVQKEVADRM
                     NAIPGTKDYGALSIAVQYYCDTEIVAKAPRHMFIPQPNVDSTVIGLHVRDKRKYDVHN
                     EDIFFKTVKASFGQRRKTLLNSLGGLGFLNKDEIREVLKEANIDEKRRGETLSIEEFS
                     VLSNIINTKVSSK"
     gene            30365..31630
                     /locus_tag="KR231_000224"
     CDS             30365..31630
                     /locus_tag="KR231_000224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0002642.1"
                     /translation="MGSKRKFKRDYIILEAKDINFRYKERVLPKAFAKVEVNDEKAII
                     ALYVENLKYVKDGYKAVAIKDDHGLIDLGNIILNEQGRGEFVLDLEDYDDEIKGIALL
                     YERNIPLIGFKGNKLENYEDILFQEVEEEEYEEYEELEEEDEEIEDNEESDRDEGSEE
                     EYIIEEYDEDEYEDYWEDDEDIDEGELKARTEVEDSGDEEIEEFNNYKEIENYNRVKV
                     QEEYIDIEYDEEEEEEEEVFEVNREEDRFVSSKPTKSKKVQKDQNNIEKIKRANGVSQ
                     GESGNKQTSTLLMPRQIKKGLKLFKEVKPFVTDYIDKTRWWKIEINPTTLCGYTMPYL
                     GYLNVLNYTMYSDAVLHSYKYRHYLFGVQYDEYNKRKHYIYAIPGNRNEQPDNGSTGF
                     LRYQACDNRTNSLGYWLCFIDSRQRNIVR"
     gene            31781..32896
                     /locus_tag="KR231_000225"
     CDS             31781..32896
                     /locus_tag="KR231_000225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20/M25/M40 family metallo-hydrolase"
                     /protein_id="HBH0002643.1"
                     /translation="MINEQRILNEFLELVQIDSLSLKEGNVAKVLVKKLEEIGCSVVI
                     DNAGEKANGETGNIIATLKGNKEGKKILFSSHMDTVTPGIGVKPIVDEANGIIKSDGT
                     TILGSDDKAGIAAILEGLRYINENNIEHTDIQVVFSICEECGLVGAKNLDYGKIDSEY
                     AFILDSGGSPGEIIVKAPAQDVINVKILGKTAHAGLEPEAGISAIMVAARAIENMNLL
                     RIDEETTANIGIINGGTATNIVTGEVNIIAEARSLKENKLDVQTKHMVETFEKAAKDF
                     GAQIEIDVNRAYTPIDVSEDSEIIKLAKKAFSNLGIEGHTESTGGGSDTNILSKNGIE
                     AITLGIGMKNAHTLSEHIAIKDLYDSAKMVVEIIKEA"
     gene            33082..33978
                     /locus_tag="KR231_000226"
     CDS             33082..33978
                     /locus_tag="KR231_000226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation transporter"
                     /protein_id="HBH0002644.1"
                     /translation="METRYEEANKITIQSILWNVVLTIIKVIAGVIGNSSAMIADGLH
                     SASDIISSIGVLIGNYVSSRPGDREHNYGHEKAETLVSFVLSILLIFVSITIGIEAIK
                     SLFNLDALSVPSILPLVVSVISILIKEYQYRITIKVAKKINSPALKADAWHHRSDALS
                     SVAAFIGIGGSILGFKPLDPIASVVVAIFVAKVGISILISSVNELMDVSVDEEEIKEL
                     KFIVADTEGVKNLGDIKTRKHGAMAYVDLTICVDENLTVKQGHDIATKLEKHIIKHME
                     FVKGITVHVEPCTNCQGNKCNN"
     gene            34048..34845
                     /locus_tag="KR231_000227"
     CDS             34048..34845
                     /locus_tag="KR231_000227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0002645.1"
                     /translation="MSKKRKLKKKAAILIGVVVFFIIYFISFRIGINMEKDKSEVPKK
                     VEKEEEDNRSLRTQIKEKKKVYISDKNIENIKIEEDMWDEIKLFFSDFKKVRNTTSSY
                     EAVYEGYSDDGVKFSTDLNFFRVYTVNKEEYYKVPVSSKDAFKKLLDESIYTSFDLLS
                     HYKDWKEVTITHGKEIKKVHRWKFDDLAHKMISKRVVGKVQPEKSKERSDYNFTINIK
                     GDNFDVKVDTMGKDYVKVTSKKNVSYYEVHTSLFDYLKNEIFEIGKK"
     gene            complement(34900..36252)
                     /locus_tag="KR231_000228"
     CDS             complement(34900..36252)
                     /locus_tag="KR231_000228"
                     /EC_number="6.3.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate--L-alanine ligase"
                     /protein_id="HBH0002646.1"
                     /translation="MNIHFIGIGGISMSALAEICINKGYQVSGSDSNESYLLDKLRDQ
                     GATIYIGQKKDNISDDVNMVVYTAAVHPDNEELVAAKEKNKLVMNRATFLGQIMREYK
                     NSIAVSGTHGKTSTTSMLSTIFEYADLDPTILVGGNLSMIGGNVKIGNSNHFITEACE
                     YVDSFLNFNPKISIVLNVEEDHLDYFSGIDEIKASFNKFGKLLPPEGYFIINGDDENI
                     DDILYDVKATIIKYGRDSDNDAVIKDIHFDNSGHGIFRIEYEGRDLGEFELSVYGLHN
                     IYNASSAIMAALVSGIDLETIRKNIKIYKGVGRRFETKGYYKNALVVDDYAHHPTELK
                     ATLAAAKKLKKSTLWCIFQPHTYTRTKSLLGEFSEAFYAADKVIITDIYAAREKDPGD
                     IHSKDLVEKLYQNNVDAIYIKEFEDIVKYLRENVKDNDLVITAGAGPIYKVADLLVEK
                     "
     gene            36471..37349
                     /gene="purR"
                     /locus_tag="KR231_000229"
     CDS             36471..37349
                     /gene="purR"
                     /locus_tag="KR231_000229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pur operon repressor"
                     /protein_id="HBH0002647.1"
                     /translation="MKFKRTERIGAIVKILSDNPNKIYTLSYFTNQFNAAKSTISEDL
                     LVVKNVFEKLHLGKVITISGAAGGVKYIPKTSIAENAEFLMELCERICDKSRILSGGF
                     LYLIDLIYDPTIAAKIGKIFASNIEYVDADYVVTMETKGIPMALMTAKAMNLPLVIIR
                     KDIKVSEGPTLSMTYVSGNSSKVESMSLPRKALKPDSKVIIIDDFMRGGGTIKGMVDL
                     MNEFGAEVIGTGVFISTTNPSEKMVKDYISLIQLDVNGDKIVVEPNLKTFKDEYRNED
                     LDEEEDSEFEFEIDED"
     gene            37505..37783
                     /gene="spoVG"
                     /locus_tag="KR231_000230"
     CDS             37505..37783
                     /gene="spoVG"
                     /locus_tag="KR231_000230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septation regulator SpoVG"
                     /protein_id="HBH0002648.1"
                     /translation="MKITDVRVRKLTEEGKMKCIVSITFDNLFVVHDIKVIEGHNGLF
                     IAMPSRKVGEGNFRDIAHPINAEMRQVLEDAVLQAYHEALVQWEVAAE"
     gene            37996..39375
                     /gene="glmU"
                     /locus_tag="KR231_000231"
     CDS             37996..39375
                     /gene="glmU"
                     /locus_tag="KR231_000231"
                     /EC_number="2.3.1.157"
                     /EC_number="2.7.7.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional UDP-N-acetylglucosamine
                     diphosphorylase/glucosamine-1-phosphate
                     N-acetyltransferase GlmU"
                     /protein_id="HBH0002649.1"
                     /translation="MNFKAIILAAGKGTRMKSKYPKVIHKVCGKEMVNHIIDVSKKSG
                     VKDTVVILGHEADVVKEKLAEEIIIAMQTEQLGTGHAVKMAKEYINDEDTIVVLCGDT
                     PLIKEETLKRLFEYHIENKYHATVLTTRVGNPTGYGRIIRDKKGDLLKIVEQKDANSE
                     EKMISEINSGIYCFNGKSLREALDLLNNNNSQGEYYLTDTAKIMRDKGLKVGAFAGST
                     IEELMGVNSRVELSKAEEIMRRRINESHMVNGVTIIDTNSTYIESDVMIGNDTIIYPG
                     VMLQGKTRIGSDCIIGMNSSITNSEIGDGTEIKNSTIIDSKVGENSTVGPYAYLRPKS
                     DLGNNVKIGDFVEVKNAIIEDGSKASHLSYIGDAHVGKNVNIGCGVVFVNYDGKNKFK
                     SIVKDNAFIGSNSNLVAPVVVEEKGYIATGSTITHDVPDGALAIARERQVIKEGWVEK
                     KNQKDDQSK"
     gene            39470..40420
                     /locus_tag="KR231_000232"
     CDS             39470..40420
                     /locus_tag="KR231_000232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003361732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate pyrophosphokinase"
                     /protein_id="HBH0002650.1"
                     /translation="MNTSGSEIKIIAGNSSKELAQKIADYIGVSVLDCEVGTFSDGEI
                     CVNMNETVRGCDVFVVQSTNSPVNDNLMELLILIDALKRASAGRITAVIPYYGYARQD
                     RKAKARDPITAKLVANLITAAGADRVLTMDLHAAQIQGYFDIPLDHLLGGTILANYFN
                     EKKIEDLVVVSPDLGSVTRSRKFANTLNGEVPIAIIDKRRPKANVCEVMNLIGDVKGK
                     NVILLDDMIDTAGTIVNAANALKEFGAKDVYACCTHGVLSGPAIERIANSEISELIVL
                     DTIQLPEEKRIDKIKIKTVAPLFGDAIRMIFSNESVSKLF"
     regulatory      41264..41349
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01786"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="cyclic di-GMP riboswitch class II; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="cyclic di-GMP"
                     /db_xref="RFAM:RF01786"
     gene            41511..42032
                     /locus_tag="KR231_000233"
     CDS             41511..42032
                     /locus_tag="KR231_000233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin-type N-terminal cleavage/methylation
                     domain-containing protein"
                     /protein_id="HBH0002651.1"
                     /translation="MKLKKNKKGFTLVELLVVIAIIGILAVVAVPALFSNINKAKVAS
                     VESDYSSVKSAALSYYSDTNKIPVTTTDKAGLTILETYMESLPDKADIGGKYKLIKVG
                     NKLVLQIGTDTEGVTLTEAQSAKLLSDIGKDKIYTGVTGDNFGDELTDTTKIDNKALY
                     IVLIDNTVMDSTK"
     gene            42184..43860
                     /locus_tag="KR231_000234"
     CDS             42184..43860
                     /locus_tag="KR231_000234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II/IV secretion system protein"
                     /protein_id="HBH0002652.1"
                     /translation="MAKKVRIGDKLVEKGYITEEQLKWALSEQKNSGKRLGEFLVQEG
                     LIDSNLLISVLKELLDIESIFLEGTEIDTLATKMVPENICKRYTVFPFKIDGNKICLA
                     MSDPQDREAVQDVRRMSGKDVEIFISSTEDINKAIGHAYAHSEINKAMTEYNKNRTGG
                     VRETVILEEDVNAAPIVRLVNNILENAVRMEASDIHIEQSENYMRVRFRIDGMLREYM
                     RMNSAPYKAVISRIKIMSDINISEKRIPQDGRIYLKVDNKPIDFRVSTMPTNRDEKIA
                     MRVLDKSNFMVSKEVLGIDEHGSKIYDELINTPYGLILVVGPTGSGKTTTLYSMLNQL
                     NTENRNLLTIEDPIEYELPGVNQSQINEKAGLTFASGLRAFMRQDPDIIMVGEIRDTE
                     TAEIAIRASLTGHLVLSTLHANTAVGAISRLLDMDVESFLITSSVLGVISQRLTRKIC
                     EHCKVSYEADIGEKKALGIDVNESVTIYRGKGCERCNNTGYKGRLGIFEMLEITPEIK
                     ELIDSSANQREILKMARKQGMVSLKEDIVKKVLNGKTTVEEMIRIILMTD"
     gene            43872..45080
                     /locus_tag="KR231_000235"
     CDS             43872..45080
                     /locus_tag="KR231_000235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system F family protein"
                     /protein_id="HBH0002653.1"
                     /translation="MKSFKYTVIKEDGKKQTDVIEANDFNEARNLLRKRNLRVIEIKE
                     SKNKNIRLSSRKRKKDLGADQISHFCRQFAIIVSSGINSISGLETLARRSTNITLREE
                     INRIVAEIKVGSTIADSMLSSKSKFPKLLGAMVATGEATGKLDEVLKSMASFYASEHR
                     VKQKLRNAATYPLIVLISSFIMIFIFTTFMVPKMINSITTVGATLPLITRIVMGFGMF
                     MKKFWIIVLLVIILFIYQFKKYLKTSVGRAHKDRVINKIPVLGKGINCMVATRFSRAL
                     YLFVSTGYPLVQGLDYIIDSVNNTMAEKILASAKDGITRGEGLAENLERYTYFDSVLV
                     QMIAIGEQTGELENISRQMAEFYEYESEIYLNRMASMIEPVLIIAVGIIVAILVVSIF
                     MPMLSIYDAM"
     gene            45095..46807
                     /locus_tag="KR231_000236"
     CDS             45095..46807
                     /locus_tag="KR231_000236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PilN domain-containing protein"
                     /protein_id="HBH0002654.1"
                     /translation="MNKVYVSYYGDSISIVEGRYKHDKDKFYVKNFNVFSIEDIAQDF
                     SKEKYALLRYALENVKLKSRHVVFCLNTRDVILKPQKLPNMDKKDLDGFMKLEMDEMM
                     ALESDEYVFSYEVSSETPDNSDGDESSLNLIIGAIQKEEVNAIVEIMHEFDLVLDRID
                     TLSTAYLRMLKNLDYNDIMVTNISDNSTIINIYKKDTLFISDNIPIKITAKDMDMQLL
                     NVVEESKGLMNYYSSRNFGKVTDTILILGKRYSNKLIYETFSSAFSSYVSQGLTEIMD
                     ISDMITGDIDEDDINSIVELLGSMIEPKGKRDFENINFLPMDILRKQIKAKQMKNILK
                     IAPIVILILAIPYLCLIFSNNLANKELENVNGEIRNIESAYYQIGNIEKMIQSKSEEI
                     KVYDMLIGKKVKWENLLDDIDKNTPSKVELTSLSTTYQNLGTNNKADNSKSNKTTTDK
                     SSNNETKSSTKSDSNGDKTDNDLNEDKTTNVSEALTGNSETNSNNTDKDDKTPLYDKI
                     PNVINIEGNAKDSSYVGQFLYKLKGLYYFKDVKLHSIKSNAEDSNYTFSMTLYLKEGV
                     LTNE"
     gene            46800..47708
                     /gene="pilO"
                     /locus_tag="KR231_000237"
     CDS             46800..47708
                     /gene="pilO"
                     /locus_tag="KR231_000237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 4a pilus biogenesis protein PilO"
                     /protein_id="HBH0002655.1"
                     /translation="MNKDIFKKDIKDIFKMEVSLKGILIKVIILLAILSYGYFGLYPQ
                     YQKYIATKNSVKQATEKLNIYKEKTALMPKYEKQLEEVESELKEKSKNLLYDMQDGLF
                     LIGLDKKMKAYNIDLTSYDVGNVKEYEHFYGISTTISVRGDYRNVKKLMAYLEEQKNV
                     TQILDYTMTSYIEPEKEEEETTNNKDLIKNVNINKDTKIYWVEGENKWHLYKDCPLIK
                     EGEIIKNDKLLDRSTNYLCNTCVLRAATEKEAKKEVVAPKAEGVVDATFKFIMYTKEN
                     TTMILDTDNPSSWRPGKYNPFKSSAK"
     gene            47735..48301
                     /locus_tag="KR231_000238"
     CDS             47735..48301
                     /locus_tag="KR231_000238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin-type N-terminal cleavage/methylation
                     domain-containing protein"
                     /protein_id="HBH0002656.1"
                     /translation="MSLYKNNEKGLTLLEVIIAVFILTIVLSISYKVFNGITSAVKKQ
                     QIITDAQVNINLINKYLNRDLENCKELTKTGSGNNYEYNIEMPDNVVKYEVSIETKKN
                     TEVYSVTRIQNNTIDTENEVREEIIYNQPLVQNNKEMKETPFKIEKQTGKSIYTVSIY
                     YNESVQESHKNSNLNNKTYTFDVMSRIG"
     gene            48338..48865
                     /locus_tag="KR231_000239"
     CDS             48338..48865
                     /locus_tag="KR231_000239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin-type N-terminal cleavage/methylation
                     domain-containing protein"
                     /protein_id="HBH0002657.1"
                     /translation="MSKKNSERGFSLIEVLVAMAIMGIVLFAFFNIINTNNKANTKND
                     TDITSLNYVQSEIENLREKIKSGEFDFDSLDKLEDGTVVYEKLIDKSKKVVYDKVLSE
                     GDVSLYDTPYEKITTIKDEDGNLIDKGNITNKIKTIVEDKSGQIYKIAVTGKSMNDYS
                     SKKEVKIVTEIFKDK"
     gene            48886..50424
                     /locus_tag="KR231_000240"
     CDS             48886..50424
                     /locus_tag="KR231_000240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425921.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0002658.1"
                     /translation="MRKWNKFKSERGAALVLVLVVVALLSIVGLIFSNQIANRIKSTK
                     TTNEGIQAKYLAETCVENSIDKAYEKLYDELEKMDNEFKSENQEKSISRSKLRNISDE
                     DFNNQDEENIEAERLGYMNNINFYLNKASSDLEKASMELKKLYDLDMLDYRDIEYVDA
                     NIISHRNSILEICKNYTSGDISKINEYILKEDIDSTTLIEAKLVNNDILLKKFLEENK
                     IENEHLNSAFSHTYKALDNISLAMQNMIEYRHTFHIDEPKVEVSNGIPDSQQYYELIQ
                     NPIINSMEYSWNSKWDTLENLLEILPNQTQGFNSLRVHLRNNVRKFEKLSDNISSGKK
                     NTAKNFLKYKELLYEISDQCNQLKSMSYEKIPVKYDNMALITTFDYIQNELLAEIKCR
                     LKELKPQEIDKTEGITIKIPFYKADYDMTKEGWPKLKENGSGAELSLMVTGDKNGIKE
                     VEVTDGKKNIIGLGVEENSNSKYKVDAIVNFNLNIDTNVVGNYDIKDKILINHDISSY
                     KKVN"
     gene            50524..51606
                     /locus_tag="KR231_000241"
     CDS             50524..51606
                     /locus_tag="KR231_000241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV pilus twitching motility protein PilT"
                     /protein_id="HBH0002659.1"
                     /translation="MYIYDLLEQGIRLNASDIHITVGTNPVARVKGGFVKLSEQILTS
                     EVTMQMAKDIAGESMFKVIEEHGEADFSASLKTGERFRVNAYRQKGNYAIAIRTITAE
                     IPTFEKLGLPESIKSFTEKHKGLVLVTGPTGSGKSTTLASMINIINEKQQKHIITLED
                     PIEYVHHHKQSLVNQREVGTDTESFHSALRAILRQDPDVILIGEMRDPETVSIALTAA
                     ETGHLVFSTLHTVGAAKTIDRIVDMFQPSQQQQIKTQLSTVCEGVVSQQLLPTADGKG
                     RIAAIELMFATPAIKNLIREGKTYQIPNMIQTGVKVGMKTMDQDLMELYKNGKITKDM
                     ALSRCTDQEFMTRMIGGVNYNGYYNR"
     gene            51587..52369
                     /locus_tag="KR231_000242"
     CDS             51587..52369
                     /locus_tag="KR231_000242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin peptidase"
                     /protein_id="HBH0002660.1"
                     /translation="MDIIIVNLYVFIVGIVFGSFFNVCIFRIPEGISISRPPSHCMSC
                     NTRLKPIDLIPVLSYLMSGRKCRYCYEKISSRYAIVELITGLLFLTVFMLYGISTSTI
                     YYLVLVSLLIIITFIDIDHFIIPDKILVFGAIFSMIFNLLFKEIPVKDSILGVFICGG
                     SVWIIVLLIEFVIKKECMGGGDIKLFAMLGFYMGVKNGLLTALLSVYVGAVYGICVII
                     ISRIKGKEYNSVIPYGPFISIGALITILSGKQLLELYFSMVI"
     gene            52471..53121
                     /locus_tag="KR231_000243"
     CDS             52471..53121
                     /locus_tag="KR231_000243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin peptidase"
                     /protein_id="HBH0002661.1"
                     /translation="MEYIIIISLFFAHLINKSLCVFCDREKKNLYNTFFIYIITVVLS
                     VLIYLKFGISVECVQYMVLIPFLIIISIVDYYTIYVYDITIVSGIIVQGIIFLAFFNI
                     VQFDYINHIFGLLIGFIIPYIIAKLTKGLGYGDVGLYSLCCFALGNNYGFYVIVLSFI
                     LAFLFFIILYITKIFKDVDIRKQIPFTPFISLSTILIIFTEYNIFNFYYNLLYKFI"
     gene            53135..53695
                     /locus_tag="KR231_000244"
     CDS             53135..53695
                     /locus_tag="KR231_000244"
                     /EC_number="3.1.1.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA hydrolase"
                     /protein_id="HBH0002662.1"
                     /translation="MYVVVGLGNPGKKYEKTRHNVGFDVIDILAKEYNISVTKIKHKA
                     LIGEGRVGTEKVLLVKPQTYMNLSGETLIDIYKYYKVDLSNIVVVYDDIDLEVGKIRI
                     RKKGSGGTHNGMKSITKCLGSNDFPRVRVGVSKPEAGQDLADFVLSRFRKEESDNINE
                     ALEKAADAIDSIIRENIDMSMNKYNG"
     gene            53712..57098
                     /gene="mfd"
                     /locus_tag="KR231_000245"
     CDS             53712..57098
                     /gene="mfd"
                     /locus_tag="KR231_000245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription-repair coupling factor"
                     /protein_id="HBH0002663.1"
                     /translation="MNDVFLYPLQNSKEYKDIINCIKNTKGSLLVNGLLPVQKPHISY
                     SIFNDLSRQMIFITSSDLEAKKVYEDLSFYMEDKVEYLGFQDIYFYHLDAKDRNEEAK
                     KLKVLLKLANKEKIILVTSIEAVLRKYIPKQVLLDSVSHYKVGDSLDLEKLTEKLVSL
                     GYERVSKIEGFGQFSIRGGIIDVFSLEYTNPIRMELFDDEIDSIRTFDVYSQKSIDKL
                     QQFSITPSREFIYPEKTTDALVKLKKETTKNTDEGTFQNIDYISSKTYFEGVENYIDY
                     IYPEENKSIFTYLADDAIVFINDITRLKERCENYINEFRENYKLNLERGLAIKNQGKL
                     LYHYTDLEYLVKDKSVVLNSLLPKSINNFSIKSIINFESREVPTFNGKVDLLVEELNR
                     LKYNGYKIILATNTLERANKLGKDLLDKGLETTISKDRDIEIKSSQVIIVPAHINSGF
                     QYKSIKFVVITDNEMIGVYKRASKTSNKKVKKGKKIESFLDLSVGDYVVHENSGVGRY
                     TGIEQITVNAIKKDYMKIVYQGGDNLYVPIDQMDKVQKYIGAEVEKVKLNKLGTNEWT
                     KAKAKVKKEIEDMTKDLIELYAKREKIQGYKFSKDTPWQAEFESLFPYQETEDQLKAI
                     EETKKDMESSKVMDRLVCGDVGYGKTEVAIRSIFKACMDQKQVAVLVPTTILAQQHYN
                     TFKERFENYPLRVEVLSRFKTPKQQKQIIEDAKKGLVDILIGTHRIISKDINLPNLGL
                     VVIDEEQRFGVKHKEALKKIKSTVDVLTLSATPIPRTLHMSLSGIRDMSVIEEPPQER
                     HPVITYVTESKESVIQDEIERELSRGGQVFFVYNRVEHIEEMASMIQKLVPDARVAVA
                     HGRMTSKSLENIILGFLNKDYDVLVCTTIIETGMDISNANTMIIYDADKMGLAQLYQL
                     RGRVGRSSRQGYAYLLYEKDKTLSEIAEKRLKAIREFTEFGSGFKIAMRDLEIRGAGN
                     ILGSQQHGHMAVIGYDLYVKMLNDAIKKVKGEPIVEEIDVEIDLSVNAYIPDNYIKDE
                     LIKIEMYKKIASIENKEDMLDIQEELEDRFSDIPKPVQTLLTIAYIKSLCKILKIEKI
                     RQLKDEILLVPITKYRTKQKIGYNIVTELEELLEKMCKVK"
     gene            57129..58124
                     /locus_tag="KR231_000246"
     CDS             57129..58124
                     /locus_tag="KR231_000246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HBH0002664.1"
                     /translation="MKKVITLVIAMILVVSVTACSSSKGETVATVEGTKISSDEFKKT
                     IALYKDSMEQTYGKDIWDKEVEKGVKYKDKFKDLILDQLITTEVIYSQAKKDNLLPKK
                     EDVEKSFKELKDAMGKDEKYKEQLKKLGIDDEFLRDQQEKDLAMQNYQSNFAKKTKIS
                     DEEMKKYYDTHKDEFKKDEVEASHILLKTVDDNNKPLSDKEKAEAKKKAEEALKEVKS
                     GEDFAKVAKKYSQDTSASDGGKLGFFSRGQMVAEFEDAAFSMKKGEVSDLVETQYGYH
                     IIKVTDRINEQTSFEDAKETIKDQLLKNKYQEQIEKLTKEAKVEKDEKVINKITI"
     gene            58248..58787
                     /gene="spoVT"
                     /locus_tag="KR231_000247"
     CDS             58248..58787
                     /gene="spoVT"
                     /locus_tag="KR231_000247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage V sporulation protein T"
                     /protein_id="HBH0002665.1"
                     /translation="MKATGIVRRIDDLGRVVIPKEIRKTLRIREGDPLEIFTAKDGEV
                     ILKKYSPIGELNEFSQEYAETLAEVLGYGVLITDLDSIIAVSKLPKKDYKEKSISDEL
                     EAIISERTVKYSKDKNILPLFKEDQKEYTSQVIMPIISASGDCIGSIVVVSKDKDTIA
                     ESEEKSLKIAANFLGKQVQ"
     gene            58907..60520
                     /locus_tag="KR231_000248"
     CDS             58907..60520
                     /locus_tag="KR231_000248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HBH0002666.1"
                     /translation="MNNNKNKDSFLKGALILGLAGVIVKIMGGFFRIPLGNMIGSEGM
                     GYYQAAYPVYTLFLTLATAGFPTAVAKLVSEKVAIGNFKGANKIFKVSHTVLFITGII
                     SFCILFFGADYIVTNVMKNPGALYSMKAIAPALLFVPAMSAYRGYFQGRQDMTKIAVS
                     QVAEQFFRVVLGLTLAYLLMKSLGQTFGAAGAISGATIGSIASMLYLVFAYMLGRKER
                     RAEIDASQRFKDERVSYIFKKLLTVAIPITIGASVMPLVNMIDNVIVIRRLMEAGFTY
                     KVANSMFGQLTGMAMATINLPAVITTAMSMSLVPAISKAYALGNKSKARKDTKSAVKV
                     TLLIVLPCAFGMASLAIPIMGLLFPHEPSSVGTILFTLTPCVLFLGLIQTLTGIIQGM
                     GKPIVPVIALCVGMLCKIVISYTLTGIPDINVLGSAFGTVTAYFVAAMINLLYVKKHM
                     NVNFSKKEFIIKPFITVMTMFIMVKLSYGALVGFLGNSISTIIAICVGGIVYVVVILG
                     IGGIKKEEILTMPKGDKLYKLLKKVKLIR"
     gene            60627..62075
                     /gene="mazG"
                     /locus_tag="KR231_000249"
     CDS             60627..62075
                     /gene="mazG"
                     /locus_tag="KR231_000249"
                     /EC_number="3.6.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside triphosphate pyrophosphohydrolase"
                     /protein_id="HBH0002667.1"
                     /translation="MGKISIVGLGPGDYSLISQGVLESLINSPKVFFRTEKHPIIDKL
                     KETIQYTSLDYFYEKEENFDNVYLKISEFIIEESAKGDLVYAVPGHPRVAEKTVSIIE
                     RLANEKHIAVEILPSMSFVDAMFNYLAIDPSEGFKLVDAFEIENSYIDLDTSMIITQV
                     YDKFIASNVKLKLMEHYDYNQEVCIVNGAGVKDLESKKFIKLCELDRNENFFDYLTSL
                     YIPKSSKKMYNTVHDLEIIVNTLRSPSGCEWDKKQTHQSLKNSVIEEAYELCNAIDNN
                     DIDEMVEELGDVLLQVIFHCQIGNEEGYFDLKEVVNGICKKLIHRHPHIFSGAKLDMS
                     KFEKTWEELKKEEKGESTITDGLRRIPKHLPALMKASKVQHKAALVGFDWDNVEDVFK
                     KIEEEYQELLDEHRVGNIKYIKEELGDLLFSIVNLARFLDIDSGEALNCTTEKFINRF
                     DFIEKSAMNLNKKLEDMTLEEMDEFWNQAKKQ"
     gene            62164..62442
                     /locus_tag="KR231_000250"
     CDS             62164..62442
                     /locus_tag="KR231_000250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003153447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HU family DNA-binding protein"
                     /protein_id="HBH0002668.1"
                     /translation="MNKAELVSKMAEKSGLTKKEAEAALNAFMSSVQDALVNNEKVQL
                     VGFGTFETRERAARQGRNPRDPEQVIDIPASKAPVFKAGKGLKDIING"
     gene            62514..62756
                     /locus_tag="KR231_000251"
     CDS             62514..62756
                     /locus_tag="KR231_000251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding S4 domain-containing protein"
                     /protein_id="HBH0002669.1"
                     /translation="MRLDKFLKVSRIIKRRTVAKDACDKGIVTINGKVAKSSSEVNIG
                     DTLEIQFGEKKMKFKINEVKEHVLKNDAKEMYKILE"
     gene            62818..63072
                     /locus_tag="KR231_000252"
     CDS             62818..63072
                     /locus_tag="KR231_000252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sporulation protein YabP"
                     /protein_id="HBH0002670.1"
                     /translation="MEQNITLKDRSKLVISGVEHIYSFNDKRVELKTSVGEMVIEGEN
                     LDMSKLSIDENIISIDGTINSMVYAKPKKPQESFLKKVFR"
     gene            63073..63606
                     /locus_tag="KR231_000253"
     CDS             63073..63606
                     /locus_tag="KR231_000253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0002671.1"
                     /translation="MIPFTQDVSIFYATIYGGILIGVLFDFYRGLRGNFKFINYFAII
                     FDVLFWFLATVIIFVTINLTEFFDLRYYHFVALFIGFILYYNTISKIVLSIINKIIRF
                     VRNSFKKVTHYIVSFLNNLYYVIIYSLHLLFDIIFYIPNIFIATRKSIKRKSNKKLKN
                     KKKSKPKKKKNKTKKRV"
     gene            63612..63896
                     /locus_tag="KR231_000254"
     CDS             63612..63896
                     /locus_tag="KR231_000254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septum formation initiator family protein"
                     /protein_id="HBH0002672.1"
                     /translation="MNLRKKFSGQIIVISLFLGISIFSMMTGFVFEYTKAKEYKKEIA
                     SLNKQLKKTEIQINSLKKDEKSYEGDLEDIARKRLNMVKPNETVYVDINR"
     gene            64009..64929
                     /locus_tag="KR231_000255"
     CDS             64009..64929
                     /locus_tag="KR231_000255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Ppx/GppA family phosphatase"
                     /protein_id="HBH0002673.1"
                     /translation="MKVGAIDIGTNSMRLLIADYRDGNFINRKKFVNTTRIGYGVDSK
                     GYIKEDAIKRNIKALKEFSDKCNDEKCEKIYCMGTSALRDSKNGDYFVKLAKEETGID
                     VDIVTGIEESNLGFKGVLEGIQGDDTIIVIDIGGGSTEFIVGDSEGIKFNKSENVGAL
                     RMTERFLKHDIIEDEEFEAMSSFIYDEIDKTLNHIKDRGLKTLIGIGGTITSLSAMNQ
                     ELEIYSMEKIHNSKIHKKEIEEILQKLIKMTLSDKKNLKGLQEKRADIITAGVKILNI
                     IMEKLEIEEITVSEYDNLEGLICQKSKKMY"
     gene            65019..67391
                     /gene="spoIIE"
                     /locus_tag="KR231_000256"
     CDS             65019..67391
                     /gene="spoIIE"
                     /locus_tag="KR231_000256"
                     /EC_number="3.1.3.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage II sporulation protein E"
                     /protein_id="HBH0002674.1"
                     /translation="MQRSVAVVKNKTVKPNVIKLISGYIDFTTAAFAVMGFLLSRSII
                     VDSVAPLGIAFFICASKIDKYKIPVFISTLLGILLSSNDFGNVAKYAVCLTIFMAMNK
                     KLKLSDSIAKVAFIGAIILLPISMGQAFFSNRYVYGLLIAGVEAIIMFISIYVFSYGI
                     GLMANVNNRMSVRTEEAISISLLLTFSIMGIGDISLFGISIRTILSTVLILLTSIVGG
                     ATMGASSGVIIGVASILNNMTSAVYMGIYSFSGLISGAFNKINKYFCILGYILSWTII
                     YLYTSGITSNMMQLRDILLGCLIVLVLPERLFNKIEKLIKSNVASNEIVYDYIMRSKN
                     LTNSRLNSIYKTYDDLADTFDKIREKDKVLDQRDIANVIDMIHNDECKSCSMRRMCWE
                     SRFNHTYTMIYNILEKIEEKGELSLNDIPKNFRKECMKPESIVKISNHYYKMFVLDYD
                     WSVKFSESRKLIANQIRSISKSIKSLSQDLEGDIMLDIEKEKNIYEQLERYDITVDKV
                     SYLTKSNSEFEISIEKKTCHDGCMCEDKIVNIISDLVGENMSVRKIGCHCLGGKCKAT
                     FVKSQKYKAVTEVSAMSRDGHILCGDNYTYMEINDGKYMMAISDGMGKGKKAYEESSA
                     TIDILEKMIDAKIKDEIVIDTINNMLLLKSSEEMFSTLDLGILDLKRGCLETIKMGAC
                     STYIKREDGEVDLISSSSLPVGILSDVKIDRKNVKVKEGDYVIMVSDGIVDAGRNNNL
                     GDNWLIYFLKNIETTNPKEISNLILDRALELQALQIEDDMTVLVTKICTK"
     gene            67742..69634
                     /gene="pepF"
                     /locus_tag="KR231_000257"
     CDS             67742..69634
                     /gene="pepF"
                     /locus_tag="KR231_000257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligoendopeptidase F"
                     /protein_id="HBH0002675.1"
                     /translation="MNRKLCKAIIPLFISIFCMLIISIKADQGYQKNNDRAITVMNNN
                     DTEDDAEKKQEIDYEKTCWNLQSLFKSDDQWKKELKSFDKDTKELKNYIGKVTKSPTH
                     LSFALNIKEKLDIRLNKLSAYVKLKQDTNKNSYKYLDMNDSMSKSYGNYMGICSDLEL
                     EILKLSNKDYKKIISNKNINRKYGAYLRDIRRNKVHYLDDKSEDILSKVSSISSLPSQ
                     VYELFRNMDRKTNLTPAQYASELESSDRENRKKAYQDELITYNDNINTIAGLITGQVK
                     KNIFYSQERGYESSLEMYLEADNVDEKVYNNLIRTVNSNMDSLHKYIDLRKKVLKLDK
                     VHSYDMFVPMVKAVDNNINYEKAQSIVYSALSPLGKEYNDVVYKAFNEKWIDVYSHEN
                     KVSGGYCLSVYENHPYILLNYNNSLGSVSTLSHELGHAVYEYLSSKNQNYFNSNPSIF
                     THEVASTTNEALLYEMLIKEAKGNDEKAYYITQYLDLIKDTLYTQTMYAEFEKTIHEL
                     VEKGKSVNALVLNDVWGQLLKKYYGQSYELDQLSKVGWARIPHFYNSFYVYKYATGCS
                     AGVSFAQDILKNGSDNYMSFLKKGSSDYPINLLKSSGINLTNTKPIENTIKKFDSLVA
                     ELEKLL"
     gene            69748..70713
                     /gene="galU"
                     /locus_tag="KR231_000258"
     CDS             69748..70713
                     /gene="galU"
                     /locus_tag="KR231_000258"
                     /EC_number="2.7.7.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UTP--glucose-1-phosphate uridylyltransferase
                     GalU"
                     /protein_id="HBH0002676.1"
                     /translation="MQVKVKKAVIPAAGLGTRFLPATKAQPKEMLPIVDKPTLQYIIE
                     EAVASGIEEILIITGRNKKSIEDHFDKSVELELDLEKKGKKELLEVVQNISNMINIHY
                     IRQKEPKGLGDAIYCARHFIGDEPFAVMLGDDIVDNDVPCLKQLTDAYEEYRTTILGV
                     QKVNQEDTNKYGIIEAKNIEGRVYKVKDMVEKPESGKAPSNIAILGRYIITPEIFDIL
                     KDLPPGKGGEVQLTDALKILSKKEAMYAYNFEGKRYDVGDKLGFLEATVDFALKKEDL
                     KEDFIKYLKHVCSEFDKNNNVLYNNTDEKIDLIEVNEARELEIQK"
     gene            71213..72817
                     /gene="rho"
                     /locus_tag="KR231_000259"
     CDS             71213..72817
                     /gene="rho"
                     /locus_tag="KR231_000259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination factor Rho"
                     /protein_id="HBH0002677.1"
                     /translation="MRRIFLILDDKVLEGLGSKTLVELREIAKELKIKSITTYKKNEL
                     IEIINSKSKNEEKVNEETKEKNEDIKEDIKNRKENIERESIEKEVEYKSPTKSYNKKE
                     IDTQNISQNQEHRNQRNDYNKTTSVNDSNKSSNISNRMVRNNNKNYYMPKQVDESKIV
                     DEFNTSKEDEVVGVLEILPDGFGFLRGSNYLSTEGDVYVSPSQIRRFNMKTGDKIKGI
                     TRHPKSGEKFRALLYVQKINDENPDTAIQRNAFETLTPIFPEERLTLETNRNEIATRI
                     IDLISPIGKGQRGLIVAPPKAGKTVLLKSVANSIAKNHPNVELIVLLIDERPEEVTDM
                     KESIEGDVIYSTFDQVSSHHVKVAEMVLNRAQRLVEHGKDVVILLDSITRLARAYNLT
                     ISPTGRTLSGGIDPGALHGPKKFFGAARNIRQGGSLTILGTALVETGSRMDDVIFEEF
                     KGTGNMELHLDRKLAEKRIFPAIDIYKSGTRRDDLLLDDEEKTALWRLRREMSNNSVM
                     EITDKVIELIKRTKDNKEFVKSIKNL"
     gene            72970..73170
                     /gene="rpmE"
                     /locus_tag="KR231_000260"
     CDS             72970..73170
                     /gene="rpmE"
                     /locus_tag="KR231_000260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018591942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L31"
                     /protein_id="HBH0002678.1"
                     /translation="MQKEIQPKYNPVEVRCACGNTFVAGSTKDEIKVEICSECHPFYT
                     GKQKNIEKGGRIDKFKKRFKMD"
     gene            73315..74208
                     /locus_tag="KR231_000261"
     CDS             73315..74208
                     /locus_tag="KR231_000261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1385 domain-containing protein"
                     /protein_id="HBH0002679.1"
                     /translation="MAKQAVGGQAVIEGVMMQSKDKRAVAVRKSDGEIALKEDRIKSW
                     VRDKNIDKIPFVRGSFVMIDTMIQGIKSLNFSSEFFMEEAEEDKFDLFIKKIFKDKAN
                     DIIIIFSLVIAMLLSAGLFIFIPTLVGGAFSKVMPNDFMLNLIEGIIRIAILFAYIVL
                     ISRSKDIERVFQYHGAEHKSIYCYENDLELTVENARKFKRLHPRCGTNFLFIVMAVSI
                     ILFAFFGWPNPILRIFMRIICVPIVAGLSYEVIRVLGKYDNGFTKIIAYPGMMLQYFT
                     TKEPDDEQLEVALEALKAVVD"
     gene            74226..75074
                     /gene="prmC"
                     /locus_tag="KR231_000262"
     CDS             74226..75074
                     /gene="prmC"
                     /locus_tag="KR231_000262"
                     /EC_number="2.1.1.297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor N(5)-glutamine
                     methyltransferase"
                     /protein_id="HBH0002680.1"
                     /translation="MTIKDIIIKYSDKLKDISDTPRLDTELLLQKTLGVDRLYIHLNL
                     NKELTEEQKTKFMGFAEERLNGRPIAYIVENREFMGLDFFVKEGVLIPRPDTETLVEE
                     IIEICREKKDVSILDIGTGSGAITISLAKYIENSKIMSFDISETALEIAKKNAIINEV
                     GEKIKYINSDLFTAISDSNIKFDIIVSNPPYIKKQDIETLHKQVKDYEPYNALEGGED
                     GLDFYRRITEQGKKYLNKCGILAYEVGHNQAEDVINIMKSNGYKKIYTKKDIQGIDRV
                     VIGYNI"
     gene            75118..76182
                     /gene="prfA"
                     /locus_tag="KR231_000263"
     CDS             75118..76182
                     /gene="prfA"
                     /locus_tag="KR231_000263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 1"
                     /protein_id="HBH0002681.1"
                     /translation="MLKKLEVLEDTYKDLSEKIGDPDVINDQKVWQKYIKEHADLEPI
                     VMKYREYKSVLDSIKESKEILQEESDEELRELAKMELAEMEEKVAPLEEEIKILLLPK
                     DPNDDKNVIVEIRGGAGGDEAALFAGDLFRMYSRYAERRRWKIELLSASDTGVGGYKE
                     VSFMIKGKGAYSRLKYESGVHRVQRIPSTESGGRIHTSTSTVAVLPEVEDVEVEINPN
                     DLRIDVFRSSGNGGQSVNTTDSAVRVTHIPTGEVVSCQDGKSQLKNKEQALKILKARL
                     YDKALAEQHKDIAAERKSQVGTGDRSERIRTYNFPQGRISDHRINLTLYKLDAFLDGD
                     IDEMIDALITVDQTEKMTAI"
     gene            76311..76991
                     /locus_tag="KR231_000264"
     CDS             76311..76991
                     /locus_tag="KR231_000264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ZIP family metal transporter"
                     /protein_id="HBH0002682.1"
                     /translation="MILKVTIIGLLAGVIGTGLGGVISAIFKREVDKYLSFFMGLSGG
                     IMLAVVVFDLMKESMDKMGIINTVIFTFVGALITMYIKTKLDVSGNMASGYLIFISIL
                     LHNLPEGLAIGSSFMSTESLGITLAIVIGLHNIPEGLAMALGLVCNKMKLSKVILFTV
                     IAGLPMGLGSFLGVYFGGVFTSLIGVFLATAGGTMMYVVLEEIFPHSKSVYCIIGFLL
                     GTMIVNYI"
     gene            77020..78060
                     /locus_tag="KR231_000265"
     CDS             77020..78060
                     /locus_tag="KR231_000265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906516.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonylcarbamoyl-AMP synthase"
                     /protein_id="HBH0002683.1"
                     /translation="MKTIISNIDINNIDYEEIKIQAKLLREGKTVIFPTETVYGLGAN
                     ALDENAVKKIYEAKGRPSDNPLIVHIYEKEEVYDLAKDISDKAKLVIEKLWPGPITII
                     LNKKDIIPYKTSGGLDTVAIRMPSNVIARAIIKEAGIPIAAPSANISGRPSPTKAKHV
                     YEEMNGRVDGIVLGGDSNFGLESTVLDLTEETPMILRPGSITKEVLEELLGEVKLDPS
                     LSKKEDNQKAKAPGMKYKHYSPNADVYIISGKRENVATKINDMIKSNRDKGLKTGVMC
                     ISRNREFYDGEVIDLGNSLEEVASNLFDALIEMDKKGVDVIYSEEFPKTGVGQAIMNR
                     LLKSAGYKVIKA"
     gene            78077..78526
                     /locus_tag="KR231_000266"
     CDS             78077..78526
                     /locus_tag="KR231_000266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="low molecular weight protein arginine
                     phosphatase"
                     /protein_id="HBH0002684.1"
                     /translation="MNILIVCTGNTCRSPMAEAILRKAIKESGRSIEEYSISSAGIST
                     ANGMGASENSIEVLKEIGIDLSNHRSKVITKKLIDESDIILTMTKSHKEILVQAVPKC
                     KEKVYTFKGFANKNEEDISDPFGGNLDIYRSTMREIMYSVNEIVKKI"
     gene            78543..78995
                     /gene="rpiB"
                     /locus_tag="KR231_000267"
     CDS             78543..78995
                     /gene="rpiB"
                     /locus_tag="KR231_000267"
                     /EC_number="5.3.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose 5-phosphate isomerase B"
                     /protein_id="HBH0002685.1"
                     /translation="MKIGLGCDHGGYNLKKEIISYLESKGIECVDYGTNNATDSVDYP
                     VYGEIVANSVINKEVDYGILCCGTGIGISLAANKVPGIRCAVVSDVFSAKMSKAHNDA
                     NMLSLGERVLGKGLALEIVEAWINTDFEGDRHARRVNMIKSIEEKHNK"
     gene            79031..79660
                     /gene="upp"
                     /locus_tag="KR231_000268"
     CDS             79031..79660
                     /gene="upp"
                     /locus_tag="KR231_000268"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil phosphoribosyltransferase"
                     /protein_id="HBH0002686.1"
                     /translation="MSKVVETNHPLIQHKLTLMRDKNTGSKDFRELLTEIAMLMGYEI
                     TKDIPLKDVEIETPIQKTSSKVVAGKKLAIIPILRAGLGMVDGLVSLMPAAKVGHVGL
                     YRDPETLKPVEYYCKLPQDIGERDIIVVDPMLATGGSAVAAIDLLKSKGAKSIKLANL
                     VAAPEGIAEVQKYHDDVDIYVASVDERLNEHGYIIPGLGDAGDRLFGTK"
     gene            79961..80776
                     /locus_tag="KR231_000269"
     CDS             79961..80776
                     /locus_tag="KR231_000269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EF2563 family selenium-dependent molybdenum
                     hydroxylase system protein"
                     /protein_id="HBH0002687.1"
                     /translation="MKNCIVVRGAGDLATAVIHKLHNSGFKVVALEIEEPLAIRRQIS
                     FCEAVYEKKVTVEGVECIFCNTEKEIEEVLSQHKVALIIDPKGEKLSKLNPIVLVDGI
                     LAKKNLGTTKDMAPLTIALGPGFCAGEDVDVVIETMRGHNLGRIITNGRAEKNTGVPG
                     AIKGFSKERVMHSQYDGIMENVCKIGDIVEKGDLLCYINNYEKKHEVRATISGVLRGL
                     LKDGAKVNKNLKILDIDPRKEEVKNAFTISDKARCIAGGVLEAILNNGIYPQN"
     gene            81002..81439
                     /locus_tag="KR231_000270"
     CDS             81002..81439
                     /locus_tag="KR231_000270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dCMP deaminase"
                     /protein_id="HBH0002688.1"
                     /translation="MRPSWDEYFMEIAEVVKKRSTCIRRQVGAVIVRDKQILTTGYNG
                     SPRNLEHCENIGCKRQELNIPSGERHELCRALHAEQNAIIQAAHNGISVDGATLYVTT
                     RPCVLCAKMCINAGILKIVYEGDYPDDMSTELLKEAGIELIKF"
     gene            81624..81851
                     /locus_tag="KR231_000271"
     CDS             81624..81851
                     /locus_tag="KR231_000271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AtpZ/AtpI family protein"
                     /protein_id="HBH0002689.1"
                     /translation="MSKRNTHTEIAKLFSLISQIGLMIVISILGCTFLGKFLDSKLNT
                     TPVLTIIFLLLGVGGAFSGVYKTLIVYTRRK"
     gene            81856..82242
                     /locus_tag="KR231_000272"
     CDS             81856..82242
                     /locus_tag="KR231_000272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP synthase subunit I"
                     /protein_id="HBH0002690.1"
                     /translation="MDIKLLNQVRSVTKGIVIFDVVLIVLMLITSTLSKPVLLGLIFG
                     SIIAMLNFRLLAISLEKSVTFPAGKAQAYASAQYAVRLFIMAVVLIASATVPHLNIIG
                     TALGLLSTKFVILSKNFINKLKRKEA"
     gene            82245..82949
                     /gene="atpB"
                     /locus_tag="KR231_000273"
     CDS             82245..82949
                     /gene="atpB"
                     /locus_tag="KR231_000273"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit A"
                     /protein_id="HBH0002691.1"
                     /translation="MNQAHYYLIGNFKISETILVSWGIMAFLAIASYFLTRNLKKVPT
                     SKVQIFLEFAVGGLAKMVTDVMGKNTVKRMPYMIPYIGSLFLFFACSNLSPLLGLRSP
                     TTDLDTTAAWAMITFFMIYFAGVKFKGLSYFKELAQPLAIMLPINIIGELARPISLSF
                     RPFGNILGGTIIMGLFYQLLGFISSLIPGLSIPIGEILIPVPLHLYFDLFAGLLQAYI
                     FIMLTMVFISSAGELD"
     gene            83018..83278
                     /gene="atpE"
                     /locus_tag="KR231_000274"
     CDS             83018..83278
                     /gene="atpE"
                     /locus_tag="KR231_000274"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421370.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP synthase F0 subunit C"
                     /protein_id="HBH0002692.1"
                     /translation="METAIVAAASAIGAGIAVATGIGAGIGQGIAAAKAAEAVGNQPE
                     AKGDITSTLLLGVAIAESSAIYGLVISIILLFVNPFFKYLGM"
     gene            83401..83898
                     /gene="atpF"
                     /locus_tag="KR231_000275"
     CDS             83401..83898
                     /gene="atpF"
                     /locus_tag="KR231_000275"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit B"
                     /protein_id="HBH0002693.1"
                     /translation="MEKALVGITWEFVFQIVNTFIIFLLLRKLLFKPVLNIIESREND
                     IKSDLVEGEKAKNEGLALKKEYESKINFAKDEGQEIIKQATIRAEQKSDDIVNTAKKD
                     ALDIKEKANKDIEQERQKVINEIKNDISNIALLAASKVIEKDLDKSKHEELIENFIKE
                     VGEAK"
     gene            83895..84440
                     /locus_tag="KR231_000276"
     CDS             83895..84440
                     /locus_tag="KR231_000276"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425856.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit delta"
                     /protein_id="HBH0002694.1"
                     /translation="MINVIANRYAEALFQLGEEENSTDVLFKELEKVVDMMTKVSKDF
                     YKVLKSPLVSKSEKKNLVEIIFSKEVSSNIKNFLKVLVDKDRISYLEDIELAYKELLN
                     KKNNVIDGVAISAIPMSETDIKELEVKLSNKYNKNVTIENVVDKTILGGVLVRIGNEQ
                     IDGTVKTRLDKMKEKLSEVIS"
     gene            84457..85959
                     /locus_tag="KR231_000277"
     CDS             84457..85959
                     /locus_tag="KR231_000277"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003405060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit alpha"
                     /protein_id="HBH0002695.1"
                     /translation="MNLKPEEISSIIKQQIKNYENKVELTDTGSVLTVGDGIASVYGL
                     EKAMSGELLEFPGEIYGMALNLEEEVVGAVILGDDSEIKEGDIVKRTGRIVEVPVGEA
                     LIGRVVNSLGQPIDGKGPIAYTKTRPVESEAPGIIDRRSVYEPLQTGIKSIDSMIPIG
                     RGQRELIIGDRQTGKTSIVIDTILNQKGKDVICIYVAIGQKRSTIAQLVSSLEKGGAL
                     DYTIVVSATASESAPLQYIAPYAGAAMGEEFMYNGKHVLIVYDDLSKQAVAYREMSLL
                     LRRPPGREAYPGDVFYLHSRLLERAAKLSDELGGGSMTALPIIETQAGDVSAYIPTNV
                     ISITDGQIYLQPELFYSGVRPAVDPGISVSRVGGSAQIKAMKKVAGTLKLAYSQYREL
                     AAFSQFGSDLDEDTKKRLAQGERIVEILKQGEHQPIKVENQVMIIYAVINNHLEDIPI
                     DNIARFESELYAFVDNNYPEISRKILGGEDFTHDLTDAINEFKEKFVVEV"
     gene            85987..86865
                     /gene="atpG"
                     /locus_tag="KR231_000278"
     CDS             85987..86865
                     /gene="atpG"
                     /locus_tag="KR231_000278"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP synthase F1 subunit gamma"
                     /protein_id="HBH0002696.1"
                     /translation="MAGAGIKAIKTRMGTVESTKQITKAMELVASSKLRKAKEKAEDS
                     REYFNTLYNTVKDIAQTTRGIRNEFLKEREVKNKCYVVVAGDRGLAGGYNSNVLKESV
                     SHMKGKKETVITVGKKAHEFFSKRNYNIAKDINSVEACGYEDATEISQTIIDLYKKGE
                     VDEVYIAYTKFKSALSQEVEILKLLPLVFEKDTDEQGMAVKEEKQNRSKVQYIPSAEA
                     VLSYIVPQFISGTVYGGILESFASEQGARRTAMESATDNANEMLSNLELSYNRARQSA
                     VTQEITEIVGGVEALK"
     gene            86878..88272
                     /gene="atpD"
                     /locus_tag="KR231_000279"
     CDS             86878..88272
                     /gene="atpD"
                     /locus_tag="KR231_000279"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit beta"
                     /protein_id="HBH0002697.1"
                     /translation="MANVGKVVQIVGAVLDVKFDSEQSLPNLLNALVIKLGDKEIVAE
                     VAQHIGDDTVRCIAMSATDGLVRGMEVVDTGGPISVPVGDETLGRIFNVLGKPVDGKP
                     APKSAPKLPIHRPAPAYDELETTAEILETGIKVVDLLAPYLKGGKIGLFGGAGVGKTV
                     LIQELINNIAKQHGGISVFSGVGERTREGNDLYGEMSESGVINKTALVFGQMNEPPGA
                     RMRVALTGLTMAEHFRDEQGQDVLLFVDNIFRFTQAGSEVSALLGRMPSAVGYQPTLA
                     TEMGALQERITSTKKGSITSVQAVYVPADDLTDPAPATTFSHLDAKTVLSRQISSLGI
                     YPAVDPLESTSRILDPSIVGKEHYEVARGVQSILQRYKELQDIIAILGMDELSDEDKL
                     IVARARKIQRFLSQSFTVAEQFTGNPGQYVPVKETVRGFKEILEGKHDDLPESAFLFV
                     GTIEDAVRKAKGSM"
     gene            88275..88535
                     /gene="atpC"
                     /locus_tag="KR231_000280"
     CDS             88275..88535
                     /gene="atpC"
                     /locus_tag="KR231_000280"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP synthase F1 subunit epsilon"
                     /protein_id="HBH0002698.1"
                     /translation="MASEFSLKVVTPSNTFYDGDVEMIVVRTTKGDKGVLKGHIPFVS
                     GIPVGTLKIKKEGSFKEAKIAEGFINVTQDKTVILTESAEWI"
     gene            88997..89377
                     /locus_tag="KR231_000281"
     CDS             88997..89377
                     /locus_tag="KR231_000281"
                     /EC_number="2.7.8.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="holo-ACP synthase"
                     /protein_id="HBH0002699.1"
                     /translation="MNIFDIGVDIIEIDRIRKAVDKNNRFLEKIFTDREIEYFNSKNF
                     KAESIAGNFAAKEAISKSIGTGIRVFNFKDIEVLRDEMGKPIVKTYNNLAKMCIDYNV
                     LEIKVSISHSKDYAIANAITIIKD"
     gene            89392..89853
                     /locus_tag="KR231_000282"
     CDS             89392..89853
                     /locus_tag="KR231_000282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421362.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HBH0002700.1"
                     /translation="MMDKTAKEIMTTDVIVAKQDDSIADVANMLIAEKIGGLPVVDSE
                     NRVVGIISETDILKKEKYIEAPLYINLLQGLIFLDDLKKVEKDIKQVAAYKVGELMSK
                     DIIKVHEDDKFDDVANVMIKKSINRVPVVDDDNKLKGIICRYDIIKALYNE"
     gene            89874..90464
                     /locus_tag="KR231_000283"
     CDS             89874..90464
                     /locus_tag="KR231_000283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0002701.1"
                     /translation="MRKKWTIVCIMFLALVIIVIGCQKRQSTKEEVYKDFQKQISDMN
                     YYSCKAEVEVVGNKSPHNYVLIHTYKKTDNYKLEVISPKHLKGKSIEYQGDKILVKNP
                     KISDVVELPNTGKNNQYLFVGDFIKNYLQNEEMKVKLSKGHLVLETFIPGDNKYFNKQ
                     VLYVNADTKNPEKMEVLDKEGVPRFTVKYKDFEYRN"
     gene            90479..91636
                     /gene="alr"
                     /locus_tag="KR231_000284"
     CDS             90479..91636
                     /gene="alr"
                     /locus_tag="KR231_000284"
                     /EC_number="5.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine racemase"
                     /protein_id="HBH0002702.1"
                     /translation="MQKITVPTWAEINLDNLRFNLNNIKNLLEEDIKICGVIKADAYG
                     HGAVEVAKLLEKEKVDYLAVARTAEGIELRQNGITLPILNLGYTPDEAFEDSIKNKIT
                     MTVYSLETAQKINEIAKSLGEKACVHVKIDSGMTRIGFQPNEESVQEIIELNKLEYID
                     LEGMFTHFATADEVSKEYTYKQANNYKFMSDKLDEAGVKIAIKHVSNSAAIMDCPDLR
                     LNMVRAGIILYGHYPSDDVFKDRLELRPAMKLKSKIGHIKQVEPGVGISYGLKYTTTG
                     KETIATVPIGYADGFTRIQKNPKVLIKGEVFDVVGRICMDQIMVRIDKDIDIKVGDEV
                     ILFGEGEVTAERIAKDLGTINYEVLCMISRRVDRVYMENNELVQINSYLLK"
     gene            91669..91956
                     /locus_tag="KR231_000285"
     CDS             91669..91956
                     /locus_tag="KR231_000285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribbon-helix-helix protein, CopG family"
                     /protein_id="HBH0002703.1"
                     /translation="MYDKSKEKIEVTLPDSLISEVDSIVQMENSNREDFAKAAFQFYI
                     TQKKKIHIKESMKTGYREMGQINLSLAELGMTVEEVSSDDKNEGKIAQGEY"
     gene            91925..92308
                     /locus_tag="KR231_000286"
     CDS             91925..92308
                     /locus_tag="KR231_000286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system PemK/MazF family
                     toxin"
                     /protein_id="HBH0002704.1"
                     /translation="MKGRLPKVSTNCEIKRGDLYYADLSPVVGSEQGGVRPVLIIQND
                     VGNKYSPTVIVSAITSQINKAKLPTHVEISSNEYGLNKDSVILLEQIRTIDKKRLREK
                     IGCLDENMMIKVDDGLQISLGLFTF"
     gene            92479..93306
                     /locus_tag="KR231_000287"
     CDS             92479..93306
                     /locus_tag="KR231_000287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HBH0002705.1"
                     /translation="MRDHKGLNEIARIIRRDIVSMIHRAKSGHPGGSLSVVEILTALY
                     FDEMNVDSSNPKMEDRDRFVLSKGHAAPALYATLAEKGYFDKEELNGLRKIGRMLQGH
                     PDMKGTPGVEISTGSLGQGFSVACGMAMASKLDNAPWNVYTLLGDGEVQEGIVWEAAM
                     SAAHYKLDNLIAFLDNNGLQIDGDIESVMSLGSIVDKFKAFGWNVIEIDGHDFDQIFA
                     ALDIAKSTVKKPTMIVAKTIKGKGISFMENQAGWHGTAPSDEELEKALLELGGADNE"
     gene            93299..94240
                     /locus_tag="KR231_000288"
     CDS             93299..94240
                     /locus_tag="KR231_000288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase family protein"
                     /protein_id="HBH0002706.1"
                     /translation="MSKMATREAYGKALVKLGQINDNVVVLDADLSKSTKTHDFYKSF
                     PDRFFNMGIAEQNLIGAACGLSTAGKIPFASTFAMFATGRAFEIIRNSVCYPKLNVKI
                     CATHAGLTVGEDGASHESVEDIAIMRAIPNMTVLVPADGVETEKIIFEIAKYNGPVYV
                     RLGRSSVPVLFDEDYKFEIGKGTVLREGKDVSIIACGIMVNEALLAQEKLQEEGISAR
                     VINMSSIKPIDKDLILESAKETNAIVTVEEHSIIGGLGSAVSEVVGESCPTIVKKVGI
                     KDTFGESGTPNELLKKYELTCDDIIKTVKEAIIAKRM"
     gene            94663..95757
                     /locus_tag="KR231_000289"
     CDS             94663..95757
                     /locus_tag="KR231_000289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0002707.1"
                     /translation="MSEKVNVKTVISFAGAYVATVIGSGFATGQEIMQFFSFYGFAGI
                     IGGIISMVLFSWMGASVMSKGKELQLKEPIKIYRVYCGKYLGIFFEWFGPLFLFGVFV
                     VMISGAGATLTEYYGLNPFVGRVGMAVVALLTVSLGLDKLSKILGGIGPIIIIFTLLV
                     GGISLAKNIGNIGEAAQVLSTVKIAKPVPNAYLSGVIYTTYNTIVVMAFLTGLGASAA
                     NKKEAICGGILGGVALMAAAIMMHLAILSDIGNLYSKAIPSLFLADKISPVIGVLFSI
                     ILILGIYTTAVPLLWSVTNRFVDDKHPKFKLITLIAAILGLIGGFLPFDKLVGILYPY
                     TGYMGVIILVCVLYRQITKTSGYQEGISDK"
     gene            95983..96399
                     /locus_tag="KR231_000290"
     CDS             95983..96399
                     /locus_tag="KR231_000290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0002708.1"
                     /translation="MNVKFNIKGIIYGVIALVFVIGGFIFIPSMFVEKSKPIDYTVLQ
                     RNSIPEKILDVMDKYTNEERALAAKIDNKIYIIVTRGNNKYGIEMDKIESVVEEGKDV
                     LRVKIKYKDKEDSFPYIVVETNMSELPDRIELNATK"
     gene            complement(96581..97150)
                     /locus_tag="KR231_000291"
     CDS             complement(96581..97150)
                     /locus_tag="KR231_000291"
                     /EC_number="6.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-formyltetrahydrofolate cyclo-ligase"
                     /protein_id="HBH0002709.1"
                     /translation="MKKEFRKKVIESRKNKNANFVLSNSNLITEKLLQMEDIRNATNI
                     MLYLNFNNEVQTDNLIKKLLSLKKIVSSPITIKENHTLIPTQITDLKEGLRIGAYGIR
                     EPNEKSPTIDIKALDVVIVPAVAYDIHCYRLGYGGGFYDRFLENLRKDAITIGIAFDF
                     QIFDSIPKETHDAQLDYIVTETRIITPNS"
     gene            97304..98461
                     /locus_tag="KR231_000292"
     CDS             97304..98461
                     /locus_tag="KR231_000292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S41 family peptidase"
                     /protein_id="HBH0002710.1"
                     /translation="MYLVISKKKAIFLGVILVIITAMVTSAFQLTLGNKVVISKELYE
                     DYKKYDKLLGLESIIKQDFYKKVSDTDLVNGAAKGLFLGTNDKYSGYYTKDEMENLIN
                     DSEGSYVGVGMYIGASKDGGLVVVPMKDSPAEKAGVKSGDKLVKVNGKSVSYKNSDEA
                     VRMMKGKKGKTVELTILREDKQLNFKVKTDQIIEKSIESKVIDNDLGYIEITQFISST
                     YTDFDKALKELKAKNIKGLVIDLRNNPGGMLDICKEVADELIGEGTIVYTKDNKGNTE
                     YLKSDKEKLGLPIVVLTNGESASAAEILTAAIVDNKEGISVGTTTFGKGLVQSVVRLK
                     DGTGYKLTTAQYFTPNGDYINEKGIKPTIEEKDENKQLDVATKWLREQIDK"
BASE COUNT        39546 a        10663 c        18137 g        30428 t
ORIGIN      
        1 tttagagtgc taactctaaa gaaactagta ttactaggtt ctataaactt attaaaaact
       61 taatagaaat attaagcata aagattatgt ggttacaata gcagagagga tacacctgtt
      121 cccattccga acacagaagt taagctctct agcgctgatg gtacttggtg ggaaactgcc
      181 tgggagagta ggacgtagcc acgtaatttt ttttattttt tgtcaaaaaa aacaaaaaat
      241 acgtatttct tttttcattt cgggaaaact aaacacagga attatggact ttataaaaat
      301 ttaattcttg aggagtgata taagtgaaaa aagttgcttt aattttagct ataataggtg
      361 cgcttaactg gggtgcaatt ggtattctag gtacagactt aataggtagt atctttggtg
      421 gaacatatga aatggtaagt agaataatat acttcattgt aggtttagct ggattatact
      481 taataccaag tttaatgtct gatgatagag aataatttat gcttttatgt taaatacctc
      541 attctaaatg tttagaatga ggtatttaat tttataaaaa tattaatttg tttctttttt
      601 aatggtaaaa tagataagaa ttgaagtttt aaaaagaagt attatgtaaa aaaggagtac
      661 tattaatata tgtttattat taatgaatta aataagattg taaatgaaga agtaatatct
      721 tttcatatgc ctggtcataa aaagggacag gtttataaaa agttaggata taaagatata
      781 ctaaaaaatt tgtataaaat ggatacaact gagatattag gaacagataa tttacacttt
      841 ccggaaggaa ttataaaaaa ttcacaaaaa aaagcatcaa gagtatttaa aagtgattat
      901 acttgctatt tagtaaatgg tagtagctgt ggaatacaat ctgcaataat gtcagtatgt
      961 agtcctaaaa gtaaaataat aacaaataga gactgtcatc agtctgttat aaatggatgt
     1021 attttaggag atatagatat agagtatgtg ccttgtgaga taagtgaaga gacaaatatc
     1081 ttaaaaggga tatctataag taatgtgatt gatataatag ataaaaactt ggatgcaaaa
     1141 gcagtactgc ttacttatcc tacatattat ggaatgacat atgatttaga atacatatgt
     1201 aattatgcac atagcaaaaa gatggtagtg atagtagatg aagcacatgg tgcgcattta
     1261 gggcttagtg agaggcttcc taaaacagct cttgagcaag gtgcagatat agttgtacag
     1321 agtacacata aaactcttcc agcatttaca caatcgtcaa tgatacatat acagggagac
     1381 cgagttgata tagataaaat attgaacatg ttaagaatta cagaatcttc aagcccttca
     1441 tatttattat tatcttctct ggaattagca gtagatatat atgaaaataa aggaaaagaa
     1501 ttaatggaag agcttttaaa taatattata actttcaaaa ataaagttga ttcaaatatt
     1561 aatatatacg acacaaatga taaaacaaaa atatttatat catctaaaaa catgggttta
     1621 acaggttatg aactagaaaa tattttgaga aataaatata acatacaagt ggagttatct
     1681 aattattatg gagttctttt aatatgtaca ataggaaata ctgctgagga tttctctagt
     1741 ttagaaacag cattaaacaa tgttgtaaag gaagacttta aatttgaaaa gttagaaaat
     1801 aaaaaatacc ctgttgttat tccaaagaaa atattaacac ctagagaagc attttataaa
     1861 actaaaaaaa gtgttaaaat atatgacagt ataggtaaag tttgtggtga atgtatagtt
     1921 ccatacccac ctggaataag tgtaatatct cctggtgaag taataagtaa agaaataata
     1981 gactatctaa tgttttgtca ttctaaaggc atgattgtga gtggattgaa agatgtagat
     2041 ttaaatttta tacaagtaat agatttagaa gacatttaaa aattatgata taaaagtaga
     2101 tagaagtaga tagtttaaaa ttgtgaagag aaataaatag actgcttata tagagatatc
     2161 taataaaagt actaaaaaag taaaaagtgt ttgtatggag gatatgaaaa tgaaaggtaa
     2221 gttaataatt atagagagtg gttcagatgc aagtggaaag gctactcaga cagaaatatt
     2281 atatgaaaga ttaaaaaaag aaggctatat gattaaaaag gtagaatatc caaattatga
     2341 atctccatca tctgccttgg tgaaaatgta cctaaaagga gactttggta aaaatgcatc
     2401 agatgtagac ccatatatag catcaacttt ttttacagct gataggtatg catcatttaa
     2461 aaccgattgg gaggagtttt acaatgaagg tggaataatt atcgcagata gatatacaac
     2521 ctctaatatg gtacatcagg cctctaaaat ggatatttgt gatagagaag agtatttaaa
     2581 ttggttagct gattatgaat ttaatttatt taagatacca caacctgatt gtgttatatt
     2641 tttagatgtg cctattgaat ttagtaaaaa gcttatggag aatagaaaaa ataaaattac
     2701 aggggaagaa aaaaaggata ttcatgaaag tgacatagag tatttagaga aatcttacaa
     2761 caatgcttta tatatagcag ataaatatga ttggaaaaaa ataaattgtg ttttagataa
     2821 caaattaaga agtattgaaa gtatacataa tgaaatttat aaaatagttc ttgattcaat
     2881 aaaacctatg gagagataaa tatgtatttt gaaaatatta tagggcaaga ttttgcaaag
     2941 aaatatttaa caaattctat aaagaaaaat aaacttaata atgcgtatat gtttgaagga
     3001 atggatggaa taggaaaaaa gaaatttgca gatgaattat caaaactatt acttgattat
     3061 gaaaatctcg aaaatagtcc agactatgta ctcataaaac cagatggaaa tagtataaaa
     3121 atagctcaaa tcagaaattt acaatcagat atagtaataa gacctcataa agactataaa
     3181 atatatataa tcaataatgc tgaaaaaatg actgtggaag ctcaaaatgc acttttaaag
     3241 acgctagagg aacctccaaa ctatgctata ataatcttag ttacaaacaa caaggaatct
     3301 ttattagaaa ctataaaatc tagatgtgat ataataaagt tctcacctat accaattgaa
     3361 gacttaaaac gttatttgat aaatacaggt atagaagaag aaagagctca attattggct
     3421 attttttcga gaggaagtat tgagaatgct ctaaatctat ctcagtcttc tgagttttca
     3481 atgatgagag aagatataca acagtatatt cagataatgt tagataaaaa catagtggag
     3541 attttaaata taccaaataa tatggaaaaa tatagaggta agattatagc tttattagat
     3601 atgatgataa actattttcg agatatcatc ctattaaaag aaaatgtaaa caagaacatg
     3661 ttaataaatg tagataagct agttttcatt caaaatatga atggaaaaat tagttattct
     3721 caattgtcca agattattga tataatagaa gatgcaaaga gtaaaataaa aagcaattgc
     3781 aatttcaata taagcataca agttatgtct ttaaatatat acgaggtgat taaatgataa
     3841 agatagtagg tataaggttt aaaagtgctg ggaaaatata ttattttgac cctgttgatt
     3901 ttaatataga gcaagatatg gatgtagttg tagaaactgc aagaggcttg gagtatggga
     3961 aagtagtcgt tggtccaaaa gatatggatg aaagcgaatt agtttctcct ttgaagccaa
     4021 ttataagaat agctacagaa gaagataaaa aagtatatct agaaaataag gaaaaggcaa
     4081 aagaaacttt tgagttgtgc caacaaaaaa taaaagaaca tgagttaaca atgtttttaa
     4141 tagattgtga gtatacattt gataggaata agttgatttt ttactttaca gcagaaggaa
     4201 gaatagattt tagagaattg gtaaaagact tagctgctat atttaaaact agaatagaac
     4261 ttagacaaat aggtgtcaga gatgaagcta aatctatagg aggtctaggg ccttgtggta
     4321 gaaaactttg ttgttcatct tggttaggtg attttcaacc agtttcaata aaaatggcaa
     4381 aagaccaaag tctatctcta aatccaacaa aaatatctgg aatatgtggg agattattct
     4441 gttgcttaaa atatgagcat gatgtatata gtgaagcaat agaaaaaatg cctgttgtag
     4501 gtgcattggt gcaatcagat gatggaaaag gaaaagttgt agaagtgaat cctttattag
     4561 aacaaattaa agtggaattt caagacaaga cagtaaagat atacacaaga gaagatataa
     4621 aaatacttag agagcctaaa aaatgtgatg gctgtggtgg taaatgtaag gataatgatg
     4681 gattagatga agccacacta agagagctaa agaaattaga agattaaatt taaggtaggg
     4741 cttttcctac cttttttaaa gcaattaatg cttaaagtta ttaatatttg aggagaattt
     4801 atatatgcaa ttaaaagatt cagaaagaat agatgattta caattaaaag gccttaaaat
     4861 tatacaagat actaatggtt tttgttttgg tatagatgca gttttattag ccaattttac
     4921 taaaataaaa aaagatgcca aagtagtaga tttgggtact ggaactggca ttatacctat
     4981 tttgatagct ggaaaaagtg aagctaaaaa aattattggc gtggaaatac aagaagatgt
     5041 atatgaaatg gcaactcgtt ctataaaatt aaatggatta gaagaaagag ttgagattat
     5101 aaatgaagat ataaaataca tagacaaagt cttagacata aatggttacc atgtagtcac
     5161 atcaaatcct ccatatatgc atattgatgg aataaaaaat ccaaatgata aaaaagcaat
     5221 atcaagacat gaagtaaggt gcaatttgga agatgtaatt agagctgcat ccagattggt
     5281 tatgcctaga ggaaaattct tcatgataca tagaccaaca agattggttg atataataac
     5341 tttagggaga aaatataaat tagaaccaaa ggttattcaa tttgtgcatc caagacctca
     5401 aaaagcaccg aacttagttt tggttcaatt tgtaaaagat ggaaggccag agcttaaaat
     5461 attggaccca ttgtatgttt atggagaaga tgggaattat acaaaagaat taaaagcaat
     5521 atataataat aaagatatag gagagttgta aatgagcggg aaattgtaca tatgtccaac
     5581 accaatagga aacctagaag atataacata tagaacttta agaatattaa aagaagtaga
     5641 cttgattgca gcagaagata caagacatag tataaaactt ttaaatcatt ttgaaatctc
     5701 aaaaccacta actagttatc atgaacataa taaggattca aagggagatt atttgataaa
     5761 taaactaatt gatggtgaaa atatagctct gataagtgat gcaggtatgc ctggtatatc
     5821 tgacccagga gaagagataa taaaacaagc tatacaaaat aacatagaga tagaagtatt
     5881 gccaggtgca acagcctttg taacggcttt agttggctct ggtatggaca cacatagatt
     5941 tatttttgag ggctttttag atagagataa aaaagttagg aaagcacaat tggaagaatt
     6001 aaaggaagaa agtagaacta taattttcta tgaatcacca catagattga aggatacact
     6061 aaaagatatg cttaaaattc ttggtaatag gaatatttct ataaatagag aacttacaaa
     6121 aaaatatcaa gaaataataa gagaaaatat agaaactacc ataaaaatat ttgaggaaaa
     6181 agaagtaaga ggagagtttg tattaatagt agagggtttt catggtgaga agtcaaagaa
     6241 agaaaattat gatgggctta cagataggga atatgtttta aaactaattg aaagtggtat
     6301 gaacaaaaaa gatgcaataa aaatagtttg taaagataga aagttaaaga aagatgtggt
     6361 ttataaacaa gttttagatt tataaaacct gaatctgagg tgattttatg gaaataggga
     6421 aaattataat agagagttta aagagggaag atacacataa aatatttata gaattagata
     6481 ataagcatga attagaaaaa ataattccta aaataagctg tatgaagtct gtaggtgaat
     6541 gtaaatatca tgtagtaaat tgttttgaac attctataaa tgcattaaaa gaattagaaa
     6601 tagtattaaa tgataaggat ttttttccaa tacatctaag aaaacatgtg tcaaactatt
     6661 taaaaacata tattgaagaa ggaataaata agttacatgt attaaagctg ggaacatttt
     6721 tacatgatat aggtaagcct gacagtatga ccttagatga aaccggaaga gttcatttca
     6781 caaatcatga aaaaataggt gctcaaataa ttgacaatat gggaataaag ttagagttat
     6841 caacagagac atatagactt ataagtaaat atgtaagata tcatatgata cttttgtctc
     6901 tatataagaa aaatgatttg agtaggaaag aattaattaa tgtatttaac ttagtagatg
     6961 aggacactat aggtgtaata atgcttgggt atgcagatat agtgtctaca gtaaaattat
     7021 tgggcaagag tggagaagtc agtgtgttaa agacatatat ggaatatatt ttaacaaatt
     7081 acttgtataa gagtaattat acacatgtat aaatttagtt aatataattg agttttagat
     7141 gattaattga agtttgaaat atacggattt caaaaacata aaagaagttg tctttgttgt
     7201 aaaattatga aagacaactt tttttatatc aaaaattgaa attttattaa ggatacttaa
     7261 tggtctatta attaataaac cattagtatt taatttatat tacaatattg attttgcttg
     7321 tattggcgtt gatagtataa cagaggtctt agtagaacca attttcttta tagtatcaat
     7381 cacattttct agctcgtaca tatcttttac aattactttt aaaagtaagc aatcatcacc
     7441 tgttatatgg tgacattcta caatcctagg gtcctttgca gctgactcaa taaattctgt
     7501 atatccattg cttggaagag aaatatgaat aaatgccttt ataactctgc ctaatgaatc
     7561 tgggttgaca atagctttat atccttctat aacaccagac tcttctaatc ttttgactct
     7621 ttctgaaact gcaggagaag ttaaaccaac tatttttcct aagtccttca tagaaattct
     7681 cccatcatcc tgtaaaattt ctatgattct gtaatctgta acatccataa ataaacagtc
     7741 ccccttaaat aaaaataatt aatgctataa aactttttta gaatctatca tttgtgtttt
     7801 taaataccaa agatttctag ataaatcaac cttataaatg tgtggttttg aaagtctttt
     7861 gtattgttcc cagatagtac ttaattcata ttgtacatga ttttttattt caagaacagc
     7921 ttttttatta tatttgcatc tgccttttat atacaatggt ttaagaagct ctttaacttt
     7981 gtaatttgta aataccttcg ttttccatgt ataagtagga tggaagattt ctaaaggttt
     8041 agactcatct ataacttcat catgtaacat aatcaaatct gcctctgcct tattgtcttc
     8101 gttatatatt cttataactt tcttgtaacc aggattattt attttttctg gattctcaga
     8161 aatctttatc ttaggttcaa gaactccttt ttcacaagat gcagctaatt tataaactcc
     8221 tccaagagaa ggtgaatcga aagatgtaat gagctttgta cctactcccc atgaatttat
     8281 agtagctcct tctgctttaa gtgatgttat ggtatattcg tctaggtcat tagatgcagt
     8341 tatgctgata tctgaaaagc cagcattatc taattgtttt ttagcttctt tagataaata
     8401 agctaaatct ccagagtcaa gtcttatacc cataggtttg tatccttttt cagaaatatt
     8461 tttgaatact tttattgcat taggaactcc actgtttaat acatcataag tatctacaag
     8521 tagtaggcat ttatctggat aaacatcagc atatgcttgg aatgcttcaa gttcattatc
     8581 aaatttttgt acccaactgt gagcttgtgt accaattata ggtatatcaa acattttccc
     8641 tgctagtacg tttgcagttc cagcacaacc accaactacg gcagccctag ccccatatat
     8701 ccctgcatct ggaccttgtg cacgacgtaa tccaaattca aatacagggt ctccttgagc
     8761 tgcaaagcaa actctagatg ctttagtagc aataagagac tgaaaattaa ctattgttaa
     8821 caatgctgtt tcaataagtt gagcttgata taaaggtgcc ttaacagtaa ttaatggctc
     8881 attagggaac atgatagttc cttcctcaac agcatatata tctcctgtga atttaaattc
     8941 ttttaaaaat tttaagaact tgtcagaaaa taaatttaag ttttttaagt actctaaatc
     9001 ttcatctgaa aaatgaagat tatctatgta ttcaacaacc tgatcaatac cacaaactat
     9061 agtataccct ccatcacaag cgttttttct aaaaaacata tcaaatacaa caatgtcttc
     9121 atgaatattc ttttcaaaat agccatttaa catagtaagc tgatataaat cagtaagaag
     9181 tgttagattt ctcattattt ctctccttaa ttattattaa atattaaaaa ttgtaaaaac
     9241 tcccacactt atactaaaac ataatatagt acaactttca agtataaagt attacctaac
     9301 tatcataaaa ttatttaaag aggaggatga ttataatagg aaaaatatgg ttttatatgg
     9361 tatcgatagg aataatagga agcttgattt ctaaaaatat gggtgaatta aataaagtta
     9421 tattaagtga aacatcaaaa ggtatagagt ttgcaataag tctagctggt atcatggcac
     9481 tctggatggg gataatgaat atcgcaaaag aatcaggttt aattgaaaag ataggtcaaa
     9541 aactaaatcc tataatgaga agattatttc cttctattcc aaaaggtcat aaagcaatgt
     9601 cttatatagt tatgaatatt gctttaaata tgttgggtgc tggaaatggt gcaacagcat
     9661 ttggtttaaa agcaatgagt gagcttcaaa ctttgaataa caagaaagat acagccacta
     9721 atgatatgat tatgtttatg gtaatcaata tatcatctat acaaataatt ccatttacta
     9781 taatcaaact aaggatggat atgggggctc aaaatccaag tgaaataatt tttacgactt
     9841 tatttgcaac cataatatct acagcagtag caataataac atgtaaattt tttcaaagaa
     9901 gatatagata aaggggatgt agatacatgg agatattttc aaacttactt ataccaataa
     9961 taattctgta catagtagtt tatggtaaat ataaaaaaat agatgtgtat gatagttttg
    10021 taaaaggagc aattgatggg ttaaaagcag catgggatat cctaccatat ataataggta
    10081 tatttttggc aataggaata ttcaaaactg gtaaaggtct tgatatgtta gaatggctat
    10141 ttacaccaat agcaaatatg atgagtatac caaaagaatt aataggtcta ataagtgtaa
    10201 aacctttatc tggaagtggt gctttaggga tgtacagtga acttgcaaat agagttggaa
    10261 taggaagttt agtagaaaaa atgggtgcta cgattgtagg ttcttctgag actatttttt
    10321 acacaatggc aatatactat ggaagtctga agataaaaaa tactagacat acattatcat
    10381 gtgctatgat tagccatgtt gcaggtgtca tagcagctgt ttttatttgc tatgtaatat
    10441 ttgtataatt tgttgacaat atgggaaaaa ttttataata tagtgattat atagaaacaa
    10501 atagtaatac aaattacaag ctatgaaaag aagagtaaat aaaggttttt tctatcagag
    10561 agctaggtta ggtgaaagct agtgtcaaaa gctttattga agatggtctt ggagcttttt
    10621 atctgagcaa gtgtgctagg gtaaaacggt tggacacgtt atagtctact aaggtatcta
    10681 taaaatgttt ctacatttca tgtgaaacat aactattata gatgaattag ggtggtaccg
    10741 tgaataatct cgcccctatg ttaactcata ggaggcgatt ttttattatt taaatgaaag
    10801 aatcatatga ttacgaacga taaaaaatta ggaggtaaat aacatgagca aaccgagttt
    10861 ttatgtaaca acaccaatat actatccaag tggaggatta cacataggac atacttattc
    10921 aacagtagct gcagatacaa tagctagatt caagcgtttc tgtggatatg atgtaaagtt
    10981 cttaacagga acagatgagc atggtgaaaa aattcaaaag aaagccatag aacaaggaat
    11041 gtcagagata gagtatcttg atggaatgat aaaagatata aaggccttat ggaatactat
    11101 ggatatatct tatgatgatt ttataagaac tacagaaaaa agacatacag acataataca
    11161 aaagatattt actaaactat atgagcaagg tgatatatat aaaggtgaat atgaaggtag
    11221 atactgtact ccttgtgaga gtttctggac agaatctcaa ttactagaag gaaataaatg
    11281 ccctgactgt ggaagagaaa catatttagt aaaagaagaa tcttatttct ttagattatc
    11341 taaatatgaa gacagattaa aagagttatt taaagatgat agtttctgtt ttcctgctgc
    11401 tagaaaaaat gaaatggtgg caaacttttt agacaaagga ttagaagatt taagcgtaac
    11461 tagaacgact tttgactggg gtataaaagt tccttttgat gaaaaacatg taatttatgt
    11521 gtgggtagat gctttatgta actatataac agcattaggt tatatgactg ataatgatga
    11581 agaatttaaa aaatattggc ctgccaatgt tcaaatagta ggtaaagaaa tagtgagatt
    11641 ccatacaata atatggccag cgcttttaat ggctttaggt ctagaagttc caaaacaagt
    11701 atttggacat ggatggatac tatttgctga tgataaaatg agtaaatcaa aaggtaatgt
    11761 ggtttatcca gaacctataa tagaaagata tggaatagac acacttaagt acttcttatt
    11821 aagagagttt gcatttgggc aagatggaag ttatactcat agaaattttg taacgagaat
    11881 aaattatgat ttagcaaatg atttaggaaa cttaataagt agaactgtag ctatggttga
    11941 aaaatacaat aatggtataa taccaacagc aaaagtttca actaattttg atgctgactt
    12001 aaaagaacaa gctgtttcaa ctagagaaaa ctttgaagct gaaatggata aaatgcaatt
    12061 ccatgaagca ttagagagtg tatggaaatt agttagaaga actaacaaat atatagatga
    12121 aactatgcct tgggcactag ctaaagatga aactaagaaa gatgaattag acacagtttt
    12181 atataattta tgtgaatcta taagaataat cgcaacacta ataaatccta taatgaatga
    12241 gactgctaat aaaatatatg aacatatagg aataaaaggt caagatgata taactacatg
    12301 ggaaagtaca aaaacatttg gtcttattgg agaaaatgta aaagtattta aaggtgaacc
    12361 tttattccca agattagatg tagaaaaaga gatagaagaa ttaactaaaa tgttctctgg
    12421 gaaacctcca gtagaagaaa aacctttaga gcataaagaa gaaattacta ttgatgattt
    12481 agacaaaata gagcttagag tagggaaaat aataagctgt gaaaaacatc caaaagcgaa
    12541 taaattatta gtatcacaag ttaagattgg accagaaaca agacaaatag tatcaggaat
    12601 agctgaatac tataagccag aggatttagt aggaaaagag gttacagtgg tatgtaactt
    12661 aaaaccagtt aaattaagag gtgtagaatc tcaaggtatg atattagcag caggtgatga
    12721 tggagaccca tatgttttac catttacaca aggggctaaa gatggatgtg aggttcgtta
    12781 gtaggtaatt aaatagtaag gagattaaag atgttatttg actcacatgc acatttaaat
    12841 gatgaaagtt ttgatgaaga tagagatgaa cttattggtt cattaaaaga taaaggtgta
    12901 gatttggttg taaatccagg agcagatata gagacgtcga taacagcaat tgaacttgcg
    12961 aaaaaatacg actttatata ttcagcagtt ggggtacatc cacatgatgt atcaaaacta
    13021 gatgatacag caatagaaac tctaagaaaa cttgcaactg agaatgaaaa agttgtagct
    13081 attggagaga ttggattaga ttattattat gattattctc caagagaaga acaaaaagag
    13141 tggtttaaga agcaaattga attagctaat gagctaaaac ttccaataat aatacatgat
    13201 agagatgcac atggagatac ttttgagata ataaagaata ctaaaaatcc tgaaatagga
    13261 tgtgtacttc attgttatag tgggaatgta gagttagcta gagaatatgt taagatgggt
    13321 tgttatatat caattccagg tacggttact tttaagaata ataaaaaaac tagagaagta
    13381 gtaagagaaa tacctctaga aagattattc atagagactg attcaccata tatgtcacca
    13441 gagccacata gaggaaagag aaacaatcct tctcaagtat cttttgttgc tgataagata
    13501 gcccaggaaa aagggatatc ttatgaagaa gtatgtagag ttacaaaaga aaatgcaaag
    13561 aaatttttta atataaaata gacaaattaa atcttataat gatatatata ataagtcatt
    13621 ataagtatag gatgagagtg cctcaaaatg agttttttag tttatgaggc actctttttg
    13681 tatgaaatca aatatatttt catcatttca acaatgaaaa agaagtttat catattttga
    13741 gatagtttgt ttttatttat ttaattcata ttttaaaata tattttctta acattgttaa
    13801 aaaagaattt acaagatatt cattagaatt aactcaactc taatattcac ttaacttaag
    13861 ttgtttatta tattattaaa gagaagtaaa cgaaaagtag attaaggagg ttgaattttg
    13921 tatacagttg atagtactaa gatattgata aatatgaact tagagaaact agaaaagata
    13981 tactcaatga taaaagatac atcaagtatt tctataatta aagaacctaa cttggctaca
    14041 gtaatggtaa gagctaatga aagtgtaaaa aacacaacat ttaatttagg agagatatta
    14101 gttactgaat gtagtgtaaa ggtagatgaa agcttgggtt acggaatagt ttcagaaaac
    14161 aataataaga aagccattta tttagcagtt atagatgcag ttttacatag caataacagt
    14221 aaatttgatg agttaaagaa ttacataaat aaaagtgtat atgaagagaa cttaaggtat
    14281 gaacaagaga ttattgatga atttagcttg attaataaaa cgaaagttca attcaatgct
    14341 atggattaaa taggaggaga atcatggtaa attatacaca agaaatatat agaaagatgc
    14401 tagatagtgc ttcatttcct gggaaattaa ataatataga taatataaat atagaaaata
    14461 atacaaaact attgaatgga gcaattggta tagcaatcac tttattagac caagaagtta
    14521 ccttctatat agaaaattat actcaaaaag atataaaaaa tataagagca cttacaatgt
    14581 caaatcaaat agattataga aaatcagatt atatattttt agatattaat tcagaagtgg
    14641 atatattaca gattaaaata ggttcttttg aatatcctga tgaaagtgca actatagtac
    14701 atcaagtaaa tgatttatca acgtactctc aaactaagta tataaagctt gatttgagtg
    14761 gtcctggtat aaaatctaaa aatagtatat atataaatgg aattagagaa gaatttatag
    14821 aaagattatc tagcataaat aaagattatc caataggaat agatttgatt ttagtagata
    14881 aaaaaggaga aattgcattt ataccaaggt catcaaaatt aagttgggag gtattataga
    14941 aatggcttat gtagcagtta aaggtggaga agaagccata ttacaggcta aaaatatact
    15001 tgagttttat agggtaaaag gagatagctt gcctatagat gtaaagcaga ttgaggaaca
    15061 aatgtcttat gctgtagaca aagtaatgtc tgaaggaagt ttatacaaca aggaactatc
    15121 agcattggct ataaaacaag ctcaaggtga tatattagaa gcctctttct atgtaagagc
    15181 tttaaggtca acaatgccta gaattacata ttcagaaccc ataaatacag aagaaatgag
    15241 aataaaaaga agaatatcag ctacttttaa agatatacca ggaggtcagt atcttggggc
    15301 aactagagac tatgaaaata gaatattgaa tgtagaatta ttagaagaag atgaaaaaaa
    15361 gaatagacat tttagagata gttttataaa tgaattagaa acagtagatg aaatccctga
    15421 atttacaaaa atatctaata tatttagaaa agaaaattta ttacaagaag aagtttgtga
    15481 aaacaaattg gaagaagtta ttgatgatat tacaagaaat agtttaagat ttccagtttc
    15541 taggtcagca aagttacagg cattaactag aggtgaaagt ggagtagtgt caggttttgc
    15601 ttatgctatt gtaagaggtt ttggtgatga acatccatat ataagtgaac ttagaactgg
    15661 taatgtattt ataaaagtaa aacatcccat ctatgaagat gaagaaataa taatagggga
    15721 tatgctggtt actgaatgtg aaatagtttc aaaagcatca caaaataaga ctgaaaattc
    15781 taaaactaat tcggaagata aaaataagat gtctttagga tatggtcttt gtatggggaa
    15841 taatgagaat aaggctatat ctatggccat actagacaaa tctttggagc caaatagtga
    15901 aaaactagca caagatgaag aatttgtatt gcttcatata gatggaatag attcattagg
    15961 atttatatct cactttaagc ttcctcacta tgtagatttt aaagcggatg tagaaagaat
    16021 aaaatagttt gaggaggtaa gtttaggtga tatataacta tggtttttta gacgaaaaca
    16081 caaaaaaaga aataagaaga aagatattaa aagcaatatc aatacctggt tatcaagttc
    16141 cctttggttc aagagagttg cctatagcta agggatgggg tactggaggt ttacaattaa
    16201 cactatcatt aattggtaaa aatgatgtag taaaagtaat tgaccaagga agtgatgatt
    16261 ctacaaatgc ttgtaatata aggagcttta ttgcaagtgt aagtaatgta gaaaccacaa
    16321 aagatacatt agaagctaca ttgattcaaa cgagacatag aataccagaa gaaaaactta
    16381 aatctaatca aatactaata tttcaagtac caataccaga aacccttaga atagtagaac
    16441 ctagtgaagt agaaacaaga agaatgcatt cagaagaaga ttatagtagg atgtgggtat
    16501 atctttatga agatatagtt agatttaatg atatatctat agcagttgaa tatccatgta
    16561 aagtaaatga tagatattta atgaatccat cacctatacc tagatttgat ataaaaaaat
    16621 taaatatgtc agacaattta ttcttgtttg gtgcaggtag agaaaaaaga atttatgcta
    16681 ttcctccata tacaaaggta gaacctttag agtttgagga ttataagttt gaagaggaaa
    16741 agtttgaagg aaaatactgt agtttatgta acagtacaaa tacattttta gatgaagtat
    16801 atgacagtga cactaatgaa aagtactata gttgctcaga tacaagttat tgtgaaaaag
    16861 ttagattaaa aaataacagt atagatgtga caataggagg tacttggaat gagtaaaata
    16921 aatgactcta aaagattaga aaatatagac aagcaagtat taataggaag aaatatcaat
    16981 cttatttatg gagatgggtg tgaaaagtgt tttgaaagca caggatatga aagcaataat
    17041 atatgtaagt attgtggttc tatagttgca tgtaataatg taaatttaga actttatgaa
    17101 ggagaagtcc ttggaattgt aggtgaatct ggttcaggaa aaagcacttt attaaaaata
    17161 ctgtttttcc aagaacatgc aaatagtgga gaagtatata tatcccatta caataaagac
    17221 acaaatatac tagagctttc agaccaaaaa aagagataca taaagaatca ttttatgggt
    17281 attgtgtatc aaaatcccca ccttggttta aatttagact ttagtagtgg tggtaatata
    17341 gcagaaaaat tattgatggc aaatttatat aatgttgaaa aaataagaga tagaggcaaa
    17401 gaacttttaa taaaaactaa tatacctgta gaaagaatag accataaacc aaaatacttt
    17461 agtgggggaa tgcaacaacg agttcaaata gcaaaagctc tttcaaataa ccctccaata
    17521 ttgctattag atgaggttac aacaggttta gatgtttctg tgcaagcgga agtattggat
    17581 ttaataagag aaatccaaag agaacttaag atttctatga tagttgtatc ccatgacttt
    17641 gatgttataa agatgcttgc tgataggaca attgtaatga aaaatggaag tgtaattgag
    17701 tctggtctta cagaccaaat aatggaggac ccacaacacc catatactca gcaacttata
    17761 aattcattgc tataaatatc gtttgtaaat aagcaaaatg ggggttttta ataaaatgaa
    17821 agaaactata cttgaagtaa ataattttag taaagacttt gagttacatg cattgaacaa
    17881 gactataacg gcatgtagta atataagttt tgaagtttca aaaggtgagt ttttaggaat
    17941 aataggtaaa tctggagcag gtaagtctac catattaaaa agtatctata aaacatatat
    18001 accaacaact ggagaaataa tttttaattc agaaatatat ggtaatgtag acctggctaa
    18061 aattggagac cgagaaatga taaatcttag aaagaaagaa ataggatatg tatcacagtt
    18121 tttaaagaca cttccacgaa taactgcaat tgaactggta gtacattctt taattgagag
    18181 tgggtttgaa aaagattgtt cgtatgatat ggcaaaagat atacttaacc aatttgaaat
    18241 aaaggaaaat ttatgggatg cgtatccaaa taatttttct ggtggagaaa aattaagatt
    18301 aaatttagct caagctatgg ttaaaaagcc tagacttttg ttacttgatg aaccaactgc
    18361 atcacttgat aatcaatcta aaatatatgt aaaagaaaaa atgttggagc ttaaaagtca
    18421 aggaactaca atgataggaa tttttcatga tatagagttt atggaaactg ttatagataa
    18481 gacctttact atgacaaaag ggactataag tgaaagtggg gtagcctaga tgataaaact
    18541 aattcataat gcaaatattg tattagaaga tatgatttta gaaaatggtc atttaatcat
    18601 agagggagat acaataaaaa aagtatcaaa tgataagatt gattacgcat ttgactttaa
    18661 tgagatagat gaaataatag atgcaaaaaa cttatatgta atacctggta ttatagatat
    18721 tcacagtgat gccattgaaa aggaaataga gccgagacca agtacattat taccatttaa
    18781 tatggcattt tatgaactag ataaaaaact acctgcaaat ggaataacta cagtttatca
    18841 ttctatatct ttaggggatg gagtaggagt tagaagtatt gataactctt taaagatgat
    18901 taaaaatatt gattcatata aaaatataga tagtaagagc ataaatcata aagttcattt
    18961 aagatatgaa gtgttgtatt atgaaggttt agaaaaggtt ttagaactat tagatgaaaa
    19021 taaaatagac tacttatcaa taatggacca ttctccagga caaggtcagt atacaaatcc
    19081 aacattttat aaagagtatg ctactaaagt gtggggagtt acagaaaatt atgtagatac
    19141 atggttagat gatttagtaa atctgcatga taatttagat tggaataaaa tagctaatat
    19201 tataggtata gccaaaacta aaaatataaa tgttgcatca catgatgatg atacattaga
    19261 aaaaatggat ttcataaaaa atataggcat aaatgtatct gaatttccta taactcttga
    19321 agttgcaaaa cattcaaaga aattgggtgt tctaacttgt ttaggtgcac cgaatattgt
    19381 aagaggtaaa tctcataata acaatttaaa agcaatggat gctatattgg aagattgttg
    19441 tgacattgtg tgttcggatt atcttccatc agctatgata aagtctatgt gtatagttgc
    19501 agaaagaata aataatttaa ataaagcagt cagtttattt acctcaaatc ctgctaaagc
    19561 agttggtata tatgatgaaa gaggtagtat aaaagaaaat aaaaaagcag atttagtttt
    19621 agtagatatt gatagtgaat atccaaaggt tgtaaatact attgtaaatg gaaaaacagt
    19681 ttataaaagg gaggtataaa gattgctaac agagttacat tgtcatacaa gtatatcaga
    19741 taataatttt actactgaag aaataataaa aaaagcagca gaaaagaata taaatatctt
    19801 agcaataaca aatcatgaca cattatctgg attggatgaa gctcttgtgc ttggagagca
    19861 ttatggaata acaataatac caggtataga aatttcagcc tatgattata aaaatagaaa
    19921 aagagttcat attcttggat ataacataga tttaaacagt caagaaataa aaaatttgtg
    19981 caatccaatg gtatgtgaca gacataaagc atctgttaag atggtaaata aaattataga
    20041 tttaggatac aaaatatctc tggaagatgt aaagaaatat tcatcaaaga ctggaatatt
    20101 taaacaacat ataatgaaag ctcttataga taaaggatat acagataata tatattcaaa
    20161 tctatataaa gaattgtttc atagaggaaa cggcaaggta tatgtatctt taaaatatgt
    20221 ggattacaga gatgcaataa aagctataaa aaattctggt ggaatttgtg tgttagctca
    20281 cccgggtcaa atggataatt ttagcgctat tgaagagatg gtaaaagtag gattagatgg
    20341 aatagaagta tatcatccat ctcacaacaa agaactagaa aaagagtcgc tttcttatgc
    20401 taagaagtat aatctagtgg tcacaggagg ttcagattac cacggatttt attctcaaca
    20461 taattatgaa cttggaagca agagcttaaa taaagaagat ttatttaagt ttaggttagc
    20521 tttaggaggg gtattataaa tgtctttttt acaagtaaaa aatgtaggta aaagttatgg
    20581 acaagttaag gtgttaaaag acatatctat tgatattgaa aaaggagagt ttatttgttt
    20641 actaggtcca agtggttgtg gaaagagtac actacttaga ataattgcag ggcttgagga
    20701 taaacatggt ggaaaaataa taataaatga taaggatatg actaattcac cacctgaaag
    20761 tagaaatttt ggtatagttt ttcaatcata tgcattattt ccaaatatga atgtttacaa
    20821 aaacatagcc tttggactag aaaataaaaa cataagtaaa tctaatattg ataaaaaagt
    20881 taaagaagtt ctagaagttg tagaattaag tggatatgag aaaaaatatc catcacaatt
    20941 atcaggtgga caacaacaaa gggttgcatt agctcgtgcg attgctttag agccagactt
    21001 tttacttctt gatgaacctt tatctgcatt agatgcaaaa gtaagactta aacttaggga
    21061 gcagattaga agtttacata gaaaactagg cattacaact ataatggtaa cgcatgacca
    21121 agaagaagct ctttgtttag ctgataagat ggttgttatg aatagaggag aaataataca
    21181 agttggaacg ccaaaggagg tatataaaaa tccagaaaca ccttttgtag ctgattttat
    21241 aggaacaata aattttatag atgatggtat taataagata gctattagac cagaagatat
    21301 aaaagtagag tctaatagag attctaaaga taaggatata aaagtgggag aaattttaga
    21361 tatcgaattt agaggattta actatagaat tacagttgag tatcgttcta agcaaatgaa
    21421 attagatgta gtttccaaag ttgcagaaca aatgaaactg tgcataggtt ctaaaataaa
    21481 ctttaagata cctaaagaag gaattgtaca atataaatca gagggatgtg cttaatagct
    21541 aggggtgaat aaatgataac atcaaaaaat aaaagaagaa taagtgatag cacaatacaa
    21601 aaatatttct tgattttttc ggtaattgta ctaatagtat ttatattatt tccattagta
    21661 tcattattaa aaaatgcatt tatggataca agtggaaatt ttataggaat ttcaaacttt
    21721 agtaaatatg ttgaaaatcc aagtcttata gcatcattta aaaattcaat ttttgtatct
    21781 acagtctcat ctttaatatc actatgttta gcatttatat attcatacgc aataacaaga
    21841 acaaacataa agtttaaaga tttttttaaa actatgggaa tgtttccact ttttgcacca
    21901 actatgttat atggtatttc acttatatac ctttttggaa ataagggaat ctttacaacc
    21961 atgggtctgg aagtaccact atatggtcca ttaggaataa ttatttctca gattctattt
    22021 acatttccac aagctttttt aatattatct gtagcacttt cgatggctga ttatagactt
    22081 tatgaagcag cagatagctt gggtgctagt gaatttaaga aattttgcaa aataacaatt
    22141 cctggtataa agtactcatt acttagttca ttctttgtat cctttatact tgcatttaca
    22201 gattttggag cagctaaggt agtcggagga aactacaatg tactggctac tgacatatat
    22261 aaacaagtag ttggacaatt taacatacca atgggagcta ctgtttctat ggtaatgtta
    22321 attcctgtac taatagcatt tacattagat aagatggcaa gtaagaaaca aggtatgacc
    22381 ataactgcaa agtctatgcc atataagatt aaggaaaata agtttagaga tagagtattt
    22441 ttaatagtat gtagttttat aacattgcta atttttattt taatattcgt ttcagttata
    22501 ggttcagtta taaagttatg gccatataat ttaagcttta caatggaaca ctatacattt
    22561 aaaggtattt tgggaagtgg aataaaaaca tacttaagca gtttgaaaat atcaacttta
    22621 acagcaatat ttggaactat atttgtattt tttagtgctt atatgataga aaaggtggat
    22681 aagtttccta aattaagaca aacagcttac cttttatcaa tgataccaat ggccttacct
    22741 ggcttagttt taggtatatc atatataact ttttttaact cagcaagtaa tccattaaat
    22801 tttttatatg gaagtacagc aatattagtt atagtaaatg tagttcattt ttattcagtt
    22861 tgttttataa cctcaaattc atctttaaaa atgttggata aagagtatga attagttgca
    22921 aaatccataa atattccatt ctataaagta ttttttaata taacagttcc aatgtctata
    22981 acatcaatac ttgaaatagt agtatattat tttgtaaatt caatggttac tgtttcagca
    23041 ttaatatttt tatatacacc tcaaactcag actgcatcaa tatcaatact aaagttagat
    23101 gagataggat atataggaac atcagctgct atggcagtat tagtgctttt aacaaatata
    23161 atagtaagac ttttgtacga atttgtaaca aagaaattaa aaaataacac acaaaaatgg
    23221 cagcaaaaag atgttgcata ggggaggtaa aaatgaaatt taagaagcta gtttctttag
    23281 gagtattatc aacactttta ttaagtgtaa taacaggatg tagtactgat tcatcaggtt
    23341 cagattcaaa gtctgatagt aagacaaaag gggatttaac agtttacaca gcaattgaag
    23401 aagatagtat agagccatat ttagctacat ttaaagagaa atatccagat attaaattaa
    23461 atattgttag ggcatcaaca ggagatataa cagcaagatt attagcagaa aaggataatc
    23521 ctcaagcaga tgttgtatgg ggagttgcag ccacaagctt attggttgca gatgaccagg
    23581 ggatgttaga accatatgct ccaaaaggtt ctgaagaaat agagtctgca tttaaagatg
    23641 ataaagaagt tccttcttgg gttgggatag atgcttggat gacaggtata acagtaaaca
    23701 ctaaagaatt aagtgataag aacatcccag ttcctagttc ttacgaagat ttaataaagc
    23761 cagaatataa aggtcttata tctatgccta atccatcttc ttctggtaca gggtacttaa
    23821 cagtatcagc ccttatacaa attatgggtg aagaaaaagc atggcagtat atggataaat
    23881 tgcatgagaa tattggtgta tacactcaat ctggttcagc tccagctaca tcagcagctt
    23941 caggagaata tcctattggt atatcttttg gatatagagg tataaagtta aaagaggaag
    24001 gctatccagt agaagtagta tttccaaaag aaggttctgg atgggatata gaagcaaatg
    24061 ctcttgtgaa aaaagataat ataaaagaag catcaaaagt atttttagat tgggctataa
    24121 gtaaagatgt aatgaacgaa tactctaaga actatgcagt tactactatt tctacaggaa
    24181 atccaatacc agaaggattc cctaaaaagc cattagagca aatgatagat aatgatttaa
    24241 aatcagcagc aaaaaataga gaagatatac taaataaatg gatatcaaaa tatgatggta
    24301 agacagaaaa agagagttaa gtaaaactat acaaatggag taaaaagaaa gaattttttt
    24361 aagtagattt tattataata atataagttg agaataatat aggtcaagaa aagtgaatat
    24421 tctataaaaa tgtatagagt aagtatacca ttcagtttga atggtatatt ttttattttt
    24481 agagattaat ttagaaatag atatactaca gtttaaaata gtatatttta atttcattat
    24541 taaagtatag atattatata taaagtaaat aaattattga gcgattatta ataagatatg
    24601 tataaatttt aatttgggaa cttgtgttat atatcatgaa aaaagagaaa aaataaaagg
    24661 taaattgttt cttgataact tgaaattgga agtgagaata tttaactaga gaagaattat
    24721 ttaagtttaa gtcagcttta ggaggaggaa ttataaatgt cttttttaca agtaaaaaat
    24781 gtaggtaaaa gttatggaca agttaaggtg ctaaaagaca tatctattga tattgaaaaa
    24841 ggggagttta tttgcttatt aggtccaagt ggttgtggta aaagtacatt gcttagaata
    24901 attgcaggac ttgaggataa acatgatgga aaaataataa taaatgataa ggatatgact
    24961 aactcaccac ctgaaagtag aaactttggt attgttttcc aatcatatgc actatttcca
    25021 aatatgaatg tatataaaaa tatagccttt ggattagaaa ataaaaatat aagtaaatct
    25081 gatatagata agaaggttag agatatttta gaagttgtag aattaagtgg atatgataaa
    25141 aaatatccat cacaattatc aggtggacaa caacaaaggg ttgcactagc tcgtgcgatt
    25201 gctttagagc cagacttttt gcttcttgat gaacctttat ctgcattaga tgcaaaagta
    25261 agacttaaac ttagggaaca gattaaaagt ttacatagaa aactaggcat cacaactata
    25321 atggtaacac atgaccaaga ggaagctctt tgtttagctg ataaaatggt tgttatgaat
    25381 aatggagagg taatacagat tggaactcct aaagaagtct ataaaagtcc aaaaacacct
    25441 tttgtagctg attttatagg aacaataaat tttatagatg atgatgtgaa tatgatagca
    25501 attagaccag aagatataaa ggtagaattt aatagagact ttaaagaaat tgatgtaaaa
    25561 gtaggagaga ttttggatat agaatttaga ggattcaact atagaattac agttgaatat
    25621 tgttctaagc aaataaagtt ggacgtagtt tcaaaggtag tggaacaaat gaaactatgt
    25681 gtaggttcta aaataaactt caagatacct aaagaaagaa ccatacaata taaatcagag
    25741 ggatgtgctt aatagctaga ggtggataaa tgataacaat aaaaaataaa agaagaataa
    25801 gtgatagtaa gatacaaaaa tgttttttag tttttttagt gattgcatta gtagtattta
    25861 tattatttcc attaatatca ctattaaaaa atgcatttat ggatacaagt ggaagttttg
    25921 taggaatttc aaactttagt aaatatattg aaaatcccac tcttatagca tcatttaaaa
    25981 actcaatttt tgtatctaca atttcatcct taatatcatt atgtttagcg tttatatatt
    26041 catatgcaat aacaagaacg aatataaggt ttaaaaactt ttttaaaact atgggcatat
    26101 ttccgctttt cgcaccagct atgctatatg gtatttcact tatatacctt tttggaaaca
    26161 agggaatctt tacaattata ggcatagaag taccactata tggtccatta ggaataatta
    26221 tttgtcaaat actgtttaca tttccacagg cctttttaat attatctgta gcactttcga
    26281 tggctgatta tagactttat gaagcagcag atagcttagg ggctagtgaa tttaagaagt
    26341 tcttcaaaat aacaattcct ggtataaagt attcattagt tagttcgttc tttgtatctt
    26401 ttatacttgc atttacagat tttggagcag caaagatagt tggaggaaac tacaatgtat
    26461 tggctactga catatataaa caagtggtag gtcaatttaa cataccaatg ggagctactg
    26521 tctctatggt aatgttaatt cctgtactaa tagcatttac agtagataag atagcaagta
    26581 aaaagcaagg gatgactata actgcaaagt ctatgccata taagattaag gaaaataagt
    26641 ttagagatag agtattttta atagcatgta gttttataac tttattaatc tttattttga
    26701 tatttgtttc agttataggc tcagttataa aattatggcc atatgattta agctttacaa
    26761 tggaacacta tacgtttaaa ggtatatcag gaaatggaat caaaacatat ttaagcagtt
    26821 taaaaatatc aattttaaca gcaatatttg gaactatatt tgtatttttt agtgcttata
    26881 tgatagaaaa agtggataag tttcctagac tgagacaaat atcttatttt ttatcaatga
    26941 taccaatggc attacctggt ttggctttag gtatatcgta tataactttt ttcaattcag
    27001 caagtaatcc attaaatttt ttatatggaa gtacaacaat aatggttata gccaatatag
    27061 ttcattttta ttcagtttgc tttataactt caaattcatc tttaaaaatg ttggatagag
    27121 agtatgaatt agttgcaaaa tctataaata ttccatttta taaggtgttt ttttatgtaa
    27181 cacttccaat gtccataaca tcaatacttg aagtggctgt atattacttc gtaaattcaa
    27241 tggttactgt ttcagcatta atatttttat atatacctca aactcaaact gcatcaatat
    27301 cgatactaaa gttagaagag atagggtata tagggccatc agctgctatg gcagtattag
    27361 tgtttttaac aaatataata gtaaaacttt tgtatgaatt gacaacaaag aaattaaaaa
    27421 ctaagacaca aaaatggcaa caaaaagaag ttgcatagag gaggtaaaaa tgaaatttag
    27481 gaaattagtc tctttaggaa tattatcaac acttttattg agtgtaataa ctggatgtaa
    27541 taatgcttca tcaggttcaa atttaaagtc taataataag ataaaaggag agttaacagt
    27601 ttatacagca attgaagaag atagtataga tacatattta actacattta aagagaaata
    27661 tccagatatt aaattgaatg tacttagatt atcagtagga gatataacag caagattatt
    27721 agcagaaaaa gataatccta aagcagatgt gttatggggg gttgcagcta caagtttgat
    27781 aattttagat gacaaagaaa tgctagagcc atacgctccg aaaggctttg ataaggtaaa
    27841 tcctgtattt aaagatgata agaaagttcc ttcttgggtt ggaatagatg cttggatgac
    27901 tggtataaca gtaaatacta aagaattaag tgataagaac ataccagttc ctagttctta
    27961 tgaagattta ataaagccag aatataaagg tcttatatct atgcctaatc cagcttcttc
    28021 tggaacagga tatttaacag tatcagaact tatacaaatt atgggtgaag aaaaagcatg
    28081 gcagtatatg gataaattgc ataaaaatat tggtgtatac actcagtctg gttcagcgcc
    28141 agctatatta gcagcttcag gagaatatcc cattggtata tcttttggaa atagaggtat
    28201 aaagttaaaa ggtgaaggtt atccagtaga agtagtattt ccaaaagaag gttctggatg
    28261 ggagatagaa tcaaatgcac ttgtgaaaaa agataatata aaagaagcat caaaagtatt
    28321 tttagattgg gctataagta aagatgcaat gaatgagtat tctaagaatt ttgcagttac
    28381 tacaattgac acgggaaatc cggtgccaga aggatttcca aagaatccat tagaacagat
    28441 gatagataat gatttaaaat cagcagcaag aaatagagag gctatactaa ataaatggat
    28501 agaaaaatat gatggaaaga cagaaaaaga gagctaagcc ttgcaataaa atttagtaca
    28561 aaaagcgcct agaatataag ttttatatct aggctctttt gatatattta tttaaaatgc
    28621 atatttctat ataaaaataa atagtttagt accttgatta aattaaataa aaaccttaaa
    28681 ataaagagat gtaaagaaaa actaaaaacg aataaaaggt gaatttatat gataaaagaa
    28741 ataatagtag tagagggtag agatgacgtt acagcagtta agagagcaat agatgcagaa
    28801 cttataacta caggtggatt tggatttcca aaaggtgtaa tggagcgtat aaaagctgct
    28861 aatgaaagac gtggtgttat aatatttaca gacccagatt ttgcaggtga aaaaataaga
    28921 aaaaaaatag catcagaagt tccaggatgt aaacatgcat ttctaccgag agaggaagct
    28981 aaaaaggatg gagatatagg tattgagaat gctactcctc aaagtataat agcagctctg
    29041 aataaagtta gaactgaaaa tacagaaaaa agagatgaat ttaagcaagt tgacttaatt
    29101 agaaatggtc ttataggtaa tgaagaagca tcacttagaa gagatgcact tggaaaaata
    29161 cttggaattg gatatggaaa tgcaaaacaa tttttaaata gattgaataa ttatggagtt
    29221 gaaagagaag aatttataga tgcattaaaa caaatctaaa cgtaatgttt aatgtatgaa
    29281 aaatatgtat ataaaataaa ttgtggaatt acggttaatt taagatgaat tatttataat
    29341 atacacctta ttttaaatca atgtaaatac atataaataa gtataattaa taaaattaaa
    29401 tatcaaaata agttaaaaag gagtaaataa tggatagact atcttcacat aatgcaacaa
    29461 aggaagtagt acaaaaatat aattttaaat tttcaaagtc tttaggtcaa aatttcttga
    29521 tagatagtaa tataattgat aaaatcttat ctggagctag aatcacaaga ggagataata
    29581 tcatagaagt aggacctggt ataggaactc ttactcgtga gatgggtaaa atagcagaaa
    29641 aagtagtggc tatagaaatc gatagaaatt taattcctat attgaaagat accttgtcag
    29701 atttagataa tacagaggtt gtaaatcaag atatactaaa agtagacata caggaattag
    29761 taaaagataa attaaatggt gggccagtta agcttgtagc aaatcttcca tattatataa
    29821 ctactccaat agttatgaaa tttttagagg aagacatacc tgtaacagac atagtagtca
    29881 tggttcaaaa agaagttgca gatagaatga atgctattcc gggtactaaa gattatgggg
    29941 cattatctat agctgttcaa tactattgtg atacagagat tgtggcaaaa gctccaagac
    30001 atatgtttat accacaacca aatgtagatt ccacagttat aggtctacat gtaagagata
    30061 aaagaaaata tgatgttcat aatgaagaca tattttttaa aacagtaaaa gcatcctttg
    30121 gacaaagaag aaaaactctt cttaattcgt tgggaggtct tggttttctt aataaagatg
    30181 aaataagaga agtattaaaa gaagctaata tagacgaaaa aagaaggggt gaaactctta
    30241 gtatagaaga gttttcagtt ctttcaaata taataaatac aaaagtatct tctaaataga
    30301 aggtactttt tttaattttg ttaacatata ttgtttagag aaactgtgtt aaggggggat
    30361 tgcagtgggt tctaaaagaa agtttaaaag agactatata atactagaag ctaaagacat
    30421 aaactttaga tacaaagaac gagtactgcc aaaagctttt gcaaaagttg aagtaaatga
    30481 tgaaaaagca attattgcat tatatgtaga aaatctaaaa tatgttaaag atgggtataa
    30541 agcagtagca ataaaagatg accatggatt aatagactta ggaaatataa ttttaaatga
    30601 acaaggaaga ggtgaatttg ttttagattt agaagattat gatgatgaga taaaaggtat
    30661 tgcattattg tatgaaagaa atataccttt aattggattt aaaggaaata agcttgaaaa
    30721 ttatgaggac atattatttc aagaggtaga ggaagaagaa tatgaagaat atgaagagtt
    30781 ggaagaagaa gacgaagaga tagaggataa tgaggaaagt gatagagacg aaggtagtga
    30841 agaagaatat attatagaag aatatgatga agatgagtat gaagactatt gggaagatga
    30901 tgaagatatt gacgaaggag agttaaaagc aagaacggaa gtagaagatt ctggtgatga
    30961 ggaaatagaa gagttcaata attataagga aatagaaaat tataataggg ttaaagtaca
    31021 ggaagaatat atagacatag aatatgatga ggaagaagag gaagaagaag aagtttttga
    31081 agtaaataga gaagaagata ggtttgtttc ctcaaaacct actaaatcaa agaaagttca
    31141 aaaagatcag aataatattg aaaaaataaa aagagctaat ggagtaagtc aaggagagag
    31201 tggaaataaa caaaccagta cattacttat gccaagacaa ataaaaaaag gtttgaaatt
    31261 atttaaagaa gtaaaacctt ttgtaacaga ttatatagat aagacaagat ggtggaaaat
    31321 agagataaat cctacaacat tgtgtggata tacaatgcct tatttaggat atttaaacgt
    31381 gttgaattac accatgtata gtgatgcagt tttacattca tataaataca gacactattt
    31441 atttggagtc cagtatgatg aatataataa gagaaaacat tatatttatg ctatcccagg
    31501 aaatagaaat gaacagccag acaatggaag cacaggattt ttaagatatc aagcttgtga
    31561 taatagaaca aatagtttag gatattggct atgttttata gattctagac aaagaaatat
    31621 agttaggtaa aaataataaa aatgaaaaaa tttagactca attcttattt tactgaaaaa
    31681 attaatgaaa tgtagtacaa aactttaaaa actattgata atatttaaat attacactac
    31741 aatatatctt gaaataccta ttatattatg gaggaaaatt atgataaacg agcaaagaat
    31801 tttaaatgag tttcttgaat tagtacagat agatagttta tctttaaaag aggggaatgt
    31861 tgctaaagta ttagttaaaa aattagaaga aataggttgt tcagtagtaa tagacaatgc
    31921 tggtgaaaaa gcaaatggag aaactggtaa tataatagct acattaaaag gaaataaaga
    31981 aggaaagaaa atattattta gttcacatat ggatacagta actccaggta taggggtaaa
    32041 acctatagtg gatgaagcaa atggaataat aaaaagtgat ggtactacaa tattaggttc
    32101 tgatgataaa gcaggtatag cagctatatt agaaggctta agatatataa atgaaaataa
    32161 tatagaacat actgatatac aagttgtatt ctctatatgt gaggaatgtg gattagttgg
    32221 agctaaaaat ttagactatg gaaaaataga ttctgaatat gcatttatat tagatagtgg
    32281 tggttctcca ggtgaaataa tagtaaaagc tcctgcacaa gatgtaataa atgttaagat
    32341 attaggaaag actgctcatg caggtcttga acctgaagct ggaataagtg ctataatggt
    32401 agctgccaga gcaatagaaa atatgaattt acttagaata gacgaagaaa caactgctaa
    32461 cataggaatt ataaacggtg gaacagctac aaatatagta acaggagaag ttaatataat
    32521 tgcagaagcc agaagtctaa aagaaaataa attagatgtt caaactaaac acatggtaga
    32581 gacttttgaa aaagctgcaa aagattttgg agctcaaatt gagatagatg tcaatagagc
    32641 atatacacca atagatgtta gtgaggattc tgaaataata aaacttgcaa agaaggcttt
    32701 ttcaaactta ggtatagaag gtcatactga atctacagga ggaggtagtg atacaaatat
    32761 attaagtaag aatggtattg aagctataac tttaggaatt ggtatgaaaa atgctcatac
    32821 actaagtgaa catatagcta taaaagactt atatgattct gctaaaatgg tagtggagat
    32881 aataaaggaa gcataaattt aaataatagt gtataatata tatatcgcct agcttaagct
    32941 aggtgatttt tcattttata gaagattgat aatctctatt gaaagtaaag agtatacatt
    33001 tgcatataag agagtgttta atttatgttc aaatgtaggt tcttaataat atttagattg
    33061 tttcataagg gaggaataaa tatggaaaca aggtatgaag aagcaaataa aataacaata
    33121 caatcaatac tttggaatgt agtattaaca ataattaagg ttatagctgg tgttattggt
    33181 aattctagcg ctatgattgc ggatggatta cattcagcat cagatattat aagttctata
    33241 ggagtactaa taggcaatta tgtatcttct agacctggag atagagagca taattatggt
    33301 catgagaaag cagagacatt agtatcattt gtgttatcaa tattgcttat tttcgtttct
    33361 ataacaatag gtatagaggc aattaaatct ttatttaact tagatgcatt aagtgttcca
    33421 tcaatattac cattagtagt atcagttatt tcaatcctga taaaagagta tcaatataga
    33481 ataacaataa aagttgctaa aaagataaat tcaccagccc taaaagctga tgcttggcat
    33541 cataggtcag atgctttatc ttcagtagct gcttttatag gtataggtgg ttctatttta
    33601 gggtttaaac cattagaccc aattgcgtca gttgtagtgg ctatatttgt agctaaagta
    33661 ggaattagta tacttataag ttctgttaat gaattgatgg atgtttcagt tgatgaagaa
    33721 gagataaaag aattaaaatt tattgtagca gatacagaag gtgttaaaaa tcttggtgat
    33781 ataaagacta gaaaacatgg agctatggca tatgtagatt tgactatatg tgtggatgaa
    33841 aatttgacag ttaagcaagg tcatgatatt gctaccaagc ttgaaaaaca tataataaaa
    33901 catatggaat ttgtaaaagg cataacagtt cacgttgaac catgtactaa ttgccaagga
    33961 aataagtgta ataattaatt aaaacttaaa aaaaagtgta aaaagttata taattgtttt
    34021 atgattataa actctagggg tggttaaatg agcaagaaaa gaaaactaaa gaaaaaagct
    34081 gcaatattaa taggagtagt tgttttcttt ataatatact ttatatcctt tagaatagga
    34141 ataaatatgg aaaaggataa aagtgaagtg ccaaagaagg tagaaaaaga agaagaagat
    34201 aataggtctt taaggactca aataaaagag aagaagaagg tttatatatc agataaaaat
    34261 atagaaaaca taaaaattga agaagatatg tgggatgaaa taaagttatt tttctcagat
    34321 tttaagaaag taagaaatac tacttcttct tacgaagcag tttatgaagg ttattctgat
    34381 gatggagtta aattttctac tgaccttaac ttttttagag tatatactgt aaataaagaa
    34441 gaatattata aagtaccagt tagttctaag gatgctttta agaaactttt agatgagagc
    34501 atatatactt cgtttgacct tttaagtcat tataaagatt ggaaagaggt tactataact
    34561 catggaaaag aaattaaaaa agttcataga tggaaatttg atgatttagc acataagatg
    34621 atttcaaaga gggttgtagg aaaagttcaa cctgagaaaa gtaaggaaag aagtgactat
    34681 aattttacta taaatataaa aggtgataat tttgatgtaa aagttgatac aatgggaaaa
    34741 gattatgtaa aagttacttc taagaaaaat gtatcttact atgaggttca tacaagttta
    34801 tttgattacc ttaaaaatga gatatttgaa attggaaaga aataagactt taagaaggct
    34861 atcaaattag atatttgata gcctaaatta ttttatatat tatttttcaa ccaacaagtc
    34921 tgcaacctta taaattggac cagcaccagc agttattact aaatcattat ccttaacatt
    34981 ttcacgtaag tattttacta tatcttcaaa ttcttttata tagatggcat ctacattgtt
    35041 ttgatataat ttctcaacca agtccttaga atgtatatct cctgggtctt tttccctagc
    35101 agcatatata tctgttatga taactttatc agcagcatag aatgcctctg aaaattcacc
    35161 taaaagagat tttgttctag tataagtatg tggctggaag atacaccata aagttgattt
    35221 ttttaatttt ttggcagcag ctaaagttgc ttttaactca gttggatgat gtgcataatc
    35281 atctactact aaagcattct tataataccc tttagtttca aatcttcttc cgacaccttt
    35341 ataaattttt atattttttc ttatagtctc taagtcaata ccagaaacaa gagctgccat
    35401 tatggcagaa gaagcattgt atatgttatg aagaccatat acagaaagtt caaattctcc
    35461 taaatctctt ccttcatatt ctattctaaa tattccatga ccactattgt caaagtgaat
    35521 atcttttatt acagcatcat tgtcagaatc tctgccgtat tttataatag tagctttaac
    35581 atcatacaat atgtcatcaa tattttcatc atcgccattt attatgaaat agccttctgg
    35641 gggtaataat tttccaaatt tgttaaaaga agctttgatt tcatctattc cagagaaata
    35701 atcaagatgg tcttcttcaa catttaaaac tatagatatc tttgggttaa aattaaggaa
    35761 actatctaca tattcacatg cttcagttat aaagtggttg gaattaccta tcttaacatt
    35821 accacctatc atacttaagt taccaccaac tagtatagtt gggtctaagt ctgcatattc
    35881 aaagattgta gataacatag atgttgtaga agtttttcca tgtgttccag aaactgctat
    35941 agaattttta tattccctca tgatttggcc taaaaaagtc gctctgttca ttaccaattt
    36001 atttttttct ttagcagcca caagttcttc attgtctgga tgaactgctg ctgtataaac
    36061 aaccatattt acatcatctg atatattatc ttttttctga ccaatataaa tagttgcccc
    36121 ttggtcccta agtttgtcta ataggtatga ttcgtttgaa tccgaacctg aaacttgata
    36181 acctttattg atacatattt cagctaatgc actcatgctg ataccgccaa ttcctataaa
    36241 gtgtatattc ataataaaac cacctttctt tttaattaag tcctacaata tgaactattt
    36301 ctgtggtata ataatataat gttcaatatt ttataattaa tatgcatata atattatatg
    36361 tattttattt ttgaatataa taaaacataa gtaatattat accacaataa gaattgttat
    36421 gcattagtta gtttaacgtt atataaaggt acttgtagga ggaaataata atgaaattta
    36481 aaagaacaga gagaattgga gcaatagtta aaatactgtc tgataatcca aataaaatat
    36541 atactttaag ttattttaca aatcaattta atgcagcaaa atcaacaata agtgaagatt
    36601 tattagttgt aaaaaatgta tttgagaagc tacatttagg taaagttata actatttcag
    36661 gagcagcagg aggagtaaaa tatataccta aaacttctat agcagaaaat gcagagttct
    36721 taatggaatt atgcgagaga atatgtgaca agtctagaat actatctggt ggttttttat
    36781 acttgattga cctaatttac gaccctacaa tagctgctaa gataggaaag atattcgcat
    36841 caaatattga gtatgtagat gcagattatg ttgtgacaat ggaaacaaaa ggtataccta
    36901 tggcacttat gactgcaaaa gctatgaatt tacctctagt tataataaga aaagatataa
    36961 aggtatcaga aggtcctaca cttagcatga catatgtgag tggaaacagt tctaaagttg
    37021 aaagtatgag tttgccaaga aaagctctta aaccagatag taaagttata attatagatg
    37081 atttcatgag gggtggaggt actataaaag gaatggtaga ccttatgaat gaatttggtg
    37141 cagaggttat aggtactgga gtattcatat ctacaacgaa tccttcagaa aaaatggtaa
    37201 aagattatat ttcgttgatt caattggatg ttaatggaga taaaatagta gtagaaccaa
    37261 acttaaagac ttttaaagat gaatatagaa atgaagattt agacgaagaa gaagattcag
    37321 aatttgaatt tgagatagat gaagattaat aaaaaaaata tttagaaaaa tatgtaaaaa
    37381 taaaaagagg atatccctag ttgttcatag aattatttaa aaaacagttt atattaattt
    37441 attccagcga taataatttt aatataaatt aatttctgtc aaaatcaaag ggggatattt
    37501 tggtatgaag ataactgacg taagagtaag aaaattaaca gaagaaggta agatgaaatg
    37561 tatagtttca ataactttcg ataatttgtt tgtagtgcat gatataaaag ttatagaagg
    37621 ccataatggg ctatttatag caatgcctag cagaaaagta ggcgaaggaa atttcagaga
    37681 tatagctcat ccaataaatg cagaaatgag acaagtttta gaagatgcag ttttacaagc
    37741 gtatcatgaa gcattagttc aatgggaagt agctgctgaa taataataaa tatataaaat
    37801 ggagagagcc cgaacattta ggctcttttt aaatgtagaa tttctattaa aatatgtact
    37861 ttttagtaaa aaagtgctat attattagtg ataatgtata tgttgtatac aaattgttag
    37921 ataaatgtat tataatgtat attgattaag agaataatac gaataaaatt aaattagatt
    37981 gaatggagtg tatcaatgaa ctttaaagct ataatccttg ctgctggcaa aggaacaaga
    38041 atgaagtcta aatacccaaa agttatacat aaagtatgtg gaaaagaaat ggttaaccat
    38101 attatagatg tttcaaaaaa atcaggggta aaagatactg tcgtgatttt aggacatgaa
    38161 gctgatgtag ttaaagaaaa gcttgcagaa gaaattataa tagccatgca aacagaacaa
    38221 cttgggacag gacatgctgt aaagatggct aaagaatata ttaatgatga agatacaata
    38281 gttgtacttt gtggagatac tccacttata aaagaagaga cactaaagag actatttgaa
    38341 tatcatatag aaaataaata tcatgctaca gttcttacaa caagagttgg aaatccaaca
    38401 ggttatggta gaataataag agataagaag ggtgaccttc ttaaaatagt ggaacaaaaa
    38461 gatgcaaatt cagaagaaaa gatgataagt gagataaact ctggaattta ttgttttaat
    38521 ggaaagagtc ttagagaagc actagatttg ctaaataata acaattcaca aggtgaatat
    38581 tatttaactg atactgctaa aataatgaga gataaaggat taaaagttgg tgcatttgca
    38641 ggttcaacta ttgaagaact tatgggcgtt aactcaagag tagaattatc aaaggcagaa
    38701 gaaattatga gacgaagaat aaatgaatct catatggtaa atggagtaac tataatagac
    38761 actaactcta cctatataga atctgatgtt atgataggca atgatactat aatatatcca
    38821 ggtgttatgt tacaaggaaa aacaaggata ggttcagatt gtataattgg aatgaattca
    38881 tctataacaa attcagaaat aggtgatggt acagaaataa aaaattcaac tataattgat
    38941 agtaaggttg gagaaaattc tactgttggg ccatatgcat acttaagacc aaagagtgac
    39001 ttaggaaata atgtaaaaat aggcgatttt gtagaagtaa aaaatgctat tatagaagat
    39061 ggctcaaaag catctcacct ttcttatata ggagatgcac atgtcggtaa aaatgtaaat
    39121 attggatgtg gagtagtatt tgtaaactat gatggtaaaa ataaatttaa atcaatagta
    39181 aaagacaatg cgtttatagg ttcaaattct aatttagttg caccagtagt tgtagaagaa
    39241 aaaggatata tagcaacagg ttcaacaata acacatgatg tcccagatgg tgctttggca
    39301 atagcaagag aaagacaagt tatcaaagaa ggatgggtag aaaaaaagaa tcaaaaagac
    39361 gaccaaagta agtaattatg tagtttatta ttttggctaa aaaatttagc tcgaaattat
    39421 tataaattat attcattagt attttaaaat tttcaggagg gttacataaa tgaatactag
    39481 cggaagcgag attaaaatta ttgcaggtaa ttcatcgaaa gagttagcac aaaaaatagc
    39541 tgactatata ggtgtatcag tactagattg tgaagtaggt acatttagtg atggtgaaat
    39601 atgtgtaaac atgaatgaga cagtaagagg ttgtgatgtg tttgtagtgc aatctactaa
    39661 cagcccagta aatgataact taatggagtt attaatctta attgatgcgt taaagagagc
    39721 atcagcaggt agaataacag cagttattcc ttactatgga tatgcaagac aagacagaaa
    39781 ggctaaggca agagatccaa tcactgctaa attagttgca aatttaataa ctgctgctgg
    39841 agcagataga gtattaacaa tggatttaca tgcagctcaa atacaaggat attttgatat
    39901 accattagac cacttactag gtggaacaat attagcaaat tattttaatg aaaagaaaat
    39961 agaagattta gtagtagtat ctcctgactt aggaagtgtt actagatcaa gaaaatttgc
    40021 taatacttta aatggagaag ttccaatagc tataatagat aaaagaagac cgaaagctaa
    40081 tgtatgcgaa gttatgaact taataggtga tgttaaaggt aaaaatgtta tactattaga
    40141 cgatatgata gatacagcag gaacaatagt taatgctgca aatgcactta aagagtttgg
    40201 agcaaaagat gtttatgctt gttgtactca tggtgtgtta tcaggtccag ctattgaaag
    40261 aattgctaat tcagaaataa gtgagttaat agttcttgat actatacaac ttcctgaaga
    40321 gaaaagaata gataagataa agataaaaac agtagctcct ttatttggag atgctataag
    40381 aatgatattc tctaatgaat cagtaagtaa attattctaa tttattgtat ttatgagagt
    40441 tgtttaaaag gatataaacc ttttgagcaa ctcttttttg attttataat tatggaatgt
    40501 tatttttttc ttgttagaaa ggtatatatt attgtaaaaa gagattatag tttaaaatta
    40561 tgtatattta agtaaaataa acttaataaa gggcatatta ttcaaaatat tatgaatata
    40621 aaaaatatta caaaaaagta ttgaaaaaat tcagattatg tagtattatg taaatataaa
    40681 taaagaaaga aagaggtgtt tccaatggga aggttagaag atgaacccct aataattaaa
    40741 tgattcagtc acaatctaaa gtgaatataa aaatctattg aaagtttatt tataagaatt
    40801 gaaaatagta tctattctat ctttagtgtt tgtgagaggg ttctggatta tataagatta
    40861 ctgtaaagaa gtaattttgc acaataagca tatctgtaaa tgaagagttt cgtttatata
    40921 atgattgtgg ctgaatcata actataatag atagaatgtt tataatagat gattttataa
    40981 aatactatat tgtaatagct tttagctttc aaataaatat tagcaaagga tggaaatgac
    41041 aatgataaaa ctaaatgata atttataaat atctccttac gatatataat aattgtaggg
    41101 agatgtttct tttttttgta gagtataatt tttctagaaa ttctgtttca atatgtaaaa
    41161 agttggtata tataaatagt ataaacagtg ttgctaaaat atggtagata ttatataata
    41221 taaatggata tgtatataca ttatgagtta tataatttga atttaataaa atagaaacgt
    41281 tgatttatgt tctgtaatgt gggcaccttg gagcatattg agttagtggt gcaaccggct
    41341 atgaaattgt atttatttat aaatactatt attttcatag ctttttttat ttaaaaaatg
    41401 gttatatgtt agaaataaat ttggttagta cgtttaaata attttactta gatttttaac
    41461 cagatatatt ataagtaagt attaattaaa aaatttaagg gggaataaaa atgaagttaa
    41521 aaaagaataa aaaaggtttc actttagtgg aattattggt agtaattgca attataggta
    41581 tattagcagt agtggcagtt ccagctttat ttagtaatat aaacaaggct aaggtagcaa
    41641 gtgttgagtc tgattatagc tcagttaaga gtgcagcatt atcttattat tcagatacta
    41701 ataagatacc agttacaaca actgataaag ctggtttaac tattttagag acttatatgg
    41761 agtctttgcc tgataaagct gatataggtg gaaaatataa attgattaaa gttggtaata
    41821 aattggtatt acagataggt acagatactg aaggagttac attaacagaa gcacaatcag
    41881 caaaattatt gagtgatata ggtaaagata aaatatatac aggtgttaca ggagataatt
    41941 ttggagacga attaacagat actacaaaaa tagataataa agctctatat atagtactta
    42001 tagataatac tgtgatggac tcaacaaaat aattaaaact atatttttat aaagaatatt
    42061 gtaaatttaa tgaaaaatat aatataaaag acaggaagaa aatcttcctg tttttttata
    42121 ctattttctt taatgttcaa ttatgaatga tgatataatt gagatagtaa aggagtgaaa
    42181 cctgtggcta aaaaagttag aataggagac aaactggtcg aaaaaggata tataacagaa
    42241 gaacagctta aatgggcact atcagaacaa aaaaacagtg gaaaaagact aggagaattt
    42301 ctagtacaag aagggcttat agatagtaac ttactaataa gtgtattaaa agaactcttg
    42361 gatatagaaa gtatattttt agaagggaca gaaatagaca ctttagctac aaaaatggtt
    42421 ccagaaaata tatgcaaaag atatactgta tttccattta aaattgatgg aaataaaata
    42481 tgtctagcca tgtcagaccc acaagataga gaagcagttc aagatgtaag gcgtatgtct
    42541 ggtaaagacg tagagatatt tatatcaagt acagaagata taaacaaagc aataggtcat
    42601 gcttatgcac attcagaaat aaataaggca atgactgagt acaacaaaaa tagaactggt
    42661 ggagtaagag aaacagtaat acttgaagaa gatgtaaatg ctgctccaat agtacgatta
    42721 gtaaataaca tactagaaaa tgctgttaga atggaagcaa gtgatataca tatagaacaa
    42781 agtgaaaatt acatgcgtgt taggtttagg atagatggaa tgttaagaga atatatgagg
    42841 atgaactcag caccatataa ggcagtaatc agccgtatca agataatgtc agatataaat
    42901 atatctgaaa agagaatacc acaggatggt agaatctatt taaaagtgga taataaaccc
    42961 atagatttta gggtttctac aatgccaact aacagggatg aaaagatagc tatgagggtt
    43021 cttgataaga gtaattttat ggttagtaaa gaagtactag gaatagacga acatggctct
    43081 aagatatatg atgaattgat aaacactcct tatggtctta tattggttgt tggccctact
    43141 ggaagtggga aaaccactac attgtattca atgttaaatc aactaaatac agaaaataga
    43201 aatctattaa caatagaaga ccctatagag tatgaattac ctggtgtaaa tcaatctcaa
    43261 ataaatgaaa aggcagggct tactttcgcc agcggactta gagcttttat gcgtcaagac
    43321 ccagatataa taatggttgg agagataaga gatactgaga cagcagaaat agcaattaga
    43381 gcttctctta caggacattt agttttaagt acattacatg caaatacagc agttggagca
    43441 atttcacgtc ttttagatat ggatgtggaa agttttttaa taacttcatc tgttttaggt
    43501 gtaatatctc aaagacttac acgaaaaata tgtgagcatt gtaaggtttc atatgaagca
    43561 gatattggag aaaaaaaggc tcttggtatt gatgtaaatg aatcagtaac tatttataga
    43621 ggaaaaggtt gtgaaaggtg taataatact ggatataaag gacgtctagg tatatttgaa
    43681 atgcttgaaa ttactccaga aataaaagag ttaatagatt catctgcaaa tcaaagagaa
    43741 attttaaaga tggctagaaa acaaggtatg gttagcttaa aagaggatat agttaaaaaa
    43801 gttttaaatg gaaagacaac agtagaagaa atgattagaa taattttgat gactgattaa
    43861 aggatgatat tatgaaaagt tttaaataca cagtaataaa agaggacgga aaaaagcaaa
    43921 ctgatgtgat tgaagccaac gattttaatg aagctagaaa tcttcttaga aagagaaatc
    43981 ttagagttat tgaaatcaaa gaaagcaaaa ataaaaatat aagattatct agtagaaaga
    44041 gaaaaaaaga cttaggagct gaccagataa gccacttttg tagacaattt gctattatag
    44101 tatcttctgg tataaatagt atttctggat tagaaacatt agctagaagg tcaactaaca
    44161 ttacattaag agaagaaatt aatcgtatag tagcagaaat aaaagtaggt tctactattg
    44221 cagattcaat gctttcatca aaatcaaagt ttccaaagtt acttggtgct atggtagcta
    44281 caggtgaagc tacaggtaaa ttagatgaag tattaaaaag tatggcttca ttttatgcaa
    44341 gtgaacacag ggttaaacaa aagcttagaa atgctgcaac atatccatta atagttttga
    44401 tttcttcatt tataatgatt tttatattta caacatttat ggtgcctaag atgattaatt
    44461 caattacaac agtaggagca actcttccac ttataacaag aattgttatg gggtttggta
    44521 tgtttatgaa gaagttttgg ataatagtac ttttagttat tatattattt atctatcagt
    44581 ttaaaaaata tctaaaaacg tcagttggaa gggctcataa agatagagtt ataaataaga
    44641 tacctgtttt aggaaaagga ataaattgta tggtagctac acgattttca agagcattgt
    44701 atctatttgt atcaacagga tacccattag ttcaagggct tgattatatt atagatagtg
    44761 taaataacac tatggcagag aagattttag catcagctaa agatggaata acaagaggag
    44821 aaggcttagc agaaaattta gagagatata cgtattttga ctctgtgttg gtacagatga
    44881 tagctatagg ggagcagaca ggggaattag agaatataag tagacagatg gcagaatttt
    44941 atgagtatga atccgagatt tatttaaata ggatggcctc aatgatagag cctgttttaa
    45001 taattgcagt tggtattata gttgcgatac tggttgtatc aatattcatg ccaatgctta
    45061 gtatatatga tgccatgtag gagggaaagg acaaatgaac aaggtttatg tatcatatta
    45121 tggcgattct atttccatag ttgagggcag atataaacac gataaggata agttttatgt
    45181 aaaaaatttt aatgtgtttt caatagagga tattgcacaa gatttttcta aggaaaagta
    45241 tgctctattg agatacgcat tagaaaatgt taagttaaaa tcaagacatg tagttttttg
    45301 tttaaataca agagatgtaa ttttaaaacc ccaaaaactt cctaatatgg acaaaaagga
    45361 tttagacgga tttatgaagc tagagatgga cgaaatgatg gctttggagt cagatgaata
    45421 tgtattttcg tatgaagtat ctagtgaaac acctgataat tcagatggcg atgaatcaag
    45481 cttaaatctt attattggag ctatacaaaa ggaagaggta aatgcaattg tagagataat
    45541 gcatgaattt gatttagtat tagatagaat agatacatta tcaacagctt acttaagaat
    45601 gcttaaaaat ttagactaca atgatataat ggtaaccaat ataagtgaca atagcacaat
    45661 tataaatata tataagaaag atactttatt tattagtgat aatataccta taaagataac
    45721 tgctaaagat atggacatgc aattattaaa tgtagtagaa gaatcaaaag gtcttatgaa
    45781 ttactattcg tcaagaaact ttggtaaggt tacggatact atattaatat taggaaaaag
    45841 atattccaat aaattaattt atgaaacttt tagctctgca ttttcaagct atgtttctca
    45901 aggccttact gagataatgg atatatctga tatgataact ggagatatag atgaagatga
    45961 tataaattca attgtagagc ttttaggaag tatgatagaa cctaaaggga aaagagattt
    46021 tgaaaatata aactttttac caatggatat acttagaaaa cagataaaag ctaaacaaat
    46081 gaaaaacata ctgaaaattg ctccaatagt tattttgatt cttgctatac cttatttatg
    46141 tttaattttt tcaaataatt tagcaaataa ggaacttgaa aatgttaatg gtgaaataag
    46201 aaatattgaa tctgcatatt atcagattgg aaatatagaa aaaatgatac agagtaaaag
    46261 cgaagaaata aaggtatatg atatgttaat tgggaaaaag gtaaagtggg aaaatttatt
    46321 ggatgatata gataaaaata ctccaagtaa agttgaacta acaagtttat caacaactta
    46381 tcaaaatctt ggaactaata ataaagctga taattcaaaa agtaataaga ctacaacaga
    46441 taaatcaagt aacaatgaaa caaaatcaag tacgaaaagt gatagtaatg gagataaaac
    46501 agataatgat ttaaatgaag ataagactac aaatgtgtca gaagcattaa ctggaaatag
    46561 tgagactaat agtaataaca cggataaaga tgataaaact ccattgtatg ataagatacc
    46621 aaatgttata aatatagaag gaaatgctaa agattcctct tatgtaggtc aatttttata
    46681 taaattaaag ggattatact atttcaagga tgttaaatta catagcataa aaagtaatgc
    46741 agaagattct aactatacat ttagtatgac attatacctg aaagaaggtg tattaactaa
    46801 tgaataaaga tatatttaaa aaagatataa aagatatatt taaaatggaa gttagtctaa
    46861 aagggattct tataaaggtt ataattttat tagctatttt atcatatggt tattttggac
    46921 tttaccctca atatcagaaa tatattgcta caaaaaattc tgtaaaacag gctactgaaa
    46981 aattaaatat atataaagag aaaactgcac ttatgccaaa atatgaaaaa caacttgagg
    47041 aagttgaaag tgaattaaaa gaaaaaagca aaaatctttt atatgatatg caagatggtc
    47101 tttttttaat aggtttagat aaaaaaatga aggcttataa tattgactta accagttatg
    47161 acgttggaaa tgttaaagaa tacgaacatt tttatggtat atcaacaaca ataagtgtta
    47221 gaggtgatta tagaaatgtc aaaaaattaa tggcttattt agaagaacaa aaaaatgtta
    47281 ctcaaatact agattataca atgacttcat atatagaacc agaaaaagaa gaggaagaaa
    47341 caacaaacaa taaggattta attaaaaatg tgaacataaa taaagataca aaaatatact
    47401 gggtggaagg cgaaaataag tggcatttat ataaggattg tccattgata aaagagggag
    47461 agattataaa aaatgacaaa cttttagata ggtctactaa ttatctatgt aatacttgtg
    47521 tacttagagc tgcaacagaa aaagaagcaa aaaaagaagt cgtagctcca aaggcagaag
    47581 gtgtagtaga tgctacattt aaatttataa tgtacactaa agagaatact acaatgatac
    47641 ttgatacaga taatccatct tcatggagac caggaaaata taatccattt aagtctagtg
    47701 cgaaataaag ctaagtaagc tttaaagata ggtgatgagt ttgtacaaaa ataatgaaaa
    47761 aggtcttact ttattagaag taataatagc tgtttttata ctgacaatag ttttaagtat
    47821 ttcttataaa gtgttcaatg gtataacatc agcagtaaaa aagcaacaga ttattacaga
    47881 tgctcaagta aatattaatc taattaataa gtatctaaat agagatttgg aaaactgtaa
    47941 agagctaact aaaactggtt caggtaataa ttatgaatac aatatagaga tgccagataa
    48001 tgttgtaaaa tatgaagttt ctatagaaac taaaaaaaat acagaggtat attctgtaac
    48061 gagaatccaa aacaatacaa ttgatacaga aaatgaagtt agagaagaga taatctataa
    48121 tcaaccacta gttcaaaata ataaagaaat gaaggaaaca ccatttaaaa tagaaaagca
    48181 aactggtaaa tctatttata ctgtaagtat atactataat gaatcggtgc aagaaagtca
    48241 taaaaatagc aatttaaata acaaaactta tacatttgat gttatgtcaa gaatagggta
    48301 ataagaattt attaaaaaat aagtaggttg ataaaatatg agtaaaaaga atagtgaaag
    48361 aggattttcc ttaattgaag tgttagtagc tatggctatt atgggaattg tactatttgc
    48421 attttttaat attatcaata ctaataacaa agcaaacact aaaaatgaca cagatataac
    48481 ttccttaaac tatgtccaaa gtgaaataga aaatctaaga gaaaagataa aaagtggaga
    48541 atttgatttt gatagtttag ataaactaga agatggaact gtcgtatatg aaaaattaat
    48601 agataaatca aaaaaagttg tatatgataa agttcttagt gaaggtgatg tgagcttata
    48661 tgatactcca tatgaaaaga ttacaacaat aaaagatgaa gatggtaatt taatcgacaa
    48721 aggaaatatt acaaataaga taaagactat tgtagaagat aaaagtggtc agatatataa
    48781 aatagctgta actgggaaaa gcatgaatga ctattcaagt aaaaaagagg ttaaaattgt
    48841 aactgaaata tttaaagata aataatttta cttgggggtg agattttgag gaagtggaat
    48901 aaatttaaaa gtgaaagagg ggcagcttta gttttagttt tggttgtagt agcattgctt
    48961 tctattgttg gattgatatt ttcaaatcag atagctaata gaataaaatc tacaaagact
    49021 actaatgaag gtatacaagc aaagtattta gcagagacat gtgtggaaaa tagtattgat
    49081 aaagcatatg aaaaattgta tgatgagctt gagaaaatgg ataatgagtt taaaagtgaa
    49141 aatcaagaaa aatccatatc taggtcaaaa ttaagaaata tatcagatga agattttaat
    49201 aatcaagatg aggaaaatat tgaagcagaa agacttggat atatgaataa tataaatttc
    49261 tatttaaata aagcttcttc agacttggaa aaagctagta tggaattgaa aaagctatat
    49321 gatttagata tgttggacta tagagacatt gaatatgtag atgcaaatat tatttcacat
    49381 agaaattcta tcttagaaat ttgcaagaat tatacttctg gagatattag taaaataaat
    49441 gaatatattc tgaaagaaga tatagactca actacattga ttgaggcaaa gttagtgaat
    49501 aatgatattc ttttaaaaaa gtttttagaa gaaaataaaa ttgaaaatga acatttaaat
    49561 tcagcctttt cacatactta taaggcatta gataacattt ctttggcgat gcaaaatatg
    49621 attgagtata gacatacgtt tcatatagat gagccaaaag tagaagtatc taatgggatt
    49681 ccagactctc aacaatatta tgaactaata caaaatccta taataaatag tatggagtat
    49741 agctggaata gtaaatggga tacattagaa aacctattgg aaattttacc aaatcaaact
    49801 caaggattta attctttaag agttcatttg agaaataatg taagaaaatt tgagaagtta
    49861 agcgataata tatctagtgg taaaaaaaat acagcaaaaa atttcttaaa gtataaagag
    49921 ttattgtatg aaatatcaga ccaatgtaat caactaaaaa gtatgtctta tgagaaaata
    49981 cctgttaaat atgataacat ggctttgata acaacttttg actatataca aaatgagctt
    50041 ttagcagaga taaaatgcag attaaaagaa ttaaaaccac aagaaattga taaaacagaa
    50101 ggtattacta taaaaatacc tttttataag gctgactacg acatgacaaa agaaggatgg
    50161 cctaaattaa aagaaaatgg ttcaggggcg gagttaagct taatggtaac tggtgataaa
    50221 aatggaataa aagaagtaga agttacagat ggtaaaaaaa atattattgg tttaggtgtt
    50281 gaagaaaatt caaattcaaa gtataaggtt gacgccattg taaactttaa tctaaatata
    50341 gatacaaatg tagttggaaa ttatgatata aaagataaaa ttttgattaa tcatgatata
    50401 agttcataca aaaaagtaaa ctaaatataa gaagcaactt agtataaata aataataaaa
    50461 taattttatt atttactact aaaaaaataa gtaaactaat agaagatatg gagagtaaat
    50521 attatgtata tttatgattt attagagcaa ggtataagac taaacgcatc agatatacac
    50581 ataacagttg gaacaaatcc tgtagctaga gtaaaaggtg gatttgtaaa actaagtgaa
    50641 caaatattga catcagaagt aacaatgcaa atggcaaaag acatagcagg ggaatctatg
    50701 tttaaagtaa tagaagaaca tggagaagct gatttttcag cttctctaaa aacaggagaa
    50761 agatttaggg taaatgcata taggcaaaaa ggaaattacg caatagcaat aaggactata
    50821 acagcagaaa ttccaacatt tgaaaaatta ggccttccag agagtataaa atcttttact
    50881 gaaaagcata aaggattagt tttagttaca ggtccaacag gaagtggtaa aagtacaaca
    50941 cttgcaagta tgataaatat aataaatgaa aaacaacaaa aacatataat tacacttgaa
    51001 gacccgatag aatatgtaca tcatcataaa caaagtttag taaatcaaag agaagtagga
    51061 actgatacag aaagttttca ttcagccctt agagctattt tgcgtcagga cccagatgta
    51121 atactaatag gagagatgag agaccctgaa actgtttcaa tagcattaac agcagcagaa
    51181 acaggtcatt tagtattttc aacactacat acagtagggg cagctaagac aattgataga
    51241 atagtagaca tgtttcaacc atcccaacag caacaaataa aaacacagtt atctacagtt
    51301 tgtgaaggtg tggtatcaca gcagttactt cctacagcag atgggaaagg cagaatagca
    51361 gcaattgaat tgatgtttgc tactccagca ataaaaaacc tgataagaga aggcaaaaca
    51421 tatcaaattc caaacatgat acaaactgga gttaaagtag gtatgaaaac tatggaccaa
    51481 gatttaatgg aactttataa aaatggaaag attacaaaag atatggcact tagtaggtgt
    51541 actgaccaag agtttatgac aagaatgata ggtggagtaa actacaatgg atattataat
    51601 cgttaatcta tatgtattta tagtgggtat agtgtttgga agtttcttta acgtctgtat
    51661 ttttaggatt ccagaaggta tatctatttc tagaccacct tctcattgta tgagttgtaa
    51721 tactagacta aagccaatag acttaatacc agtgctaagc tatttaatga gtggcagaaa
    51781 gtgtagatat tgttatgaga aaatttctag tagatatgct atagtggaat taattacagg
    51841 acttttattt ttaacagtat ttatgttata tggaatatct acatcaacta tttattattt
    51901 ggttcttgtg tctttactga ttataattac atttatagat attgaccact ttataatacc
    51961 agataaaata ttggtttttg gagctatatt ttctatgatt tttaaccttt tatttaaaga
    52021 aattccagtt aaggattcaa ttctaggtgt ttttatttgt ggaggaagtg tctggattat
    52081 agttcttttg attgaatttg taataaaaaa agagtgtatg ggtggaggag atatcaaact
    52141 atttgcaatg ctaggttttt acatgggtgt taaaaatggt cttttgacag ccttactaag
    52201 cgtttatgtg ggagcagtct atggaatctg tgtaataatt ataagtagaa taaaaggaaa
    52261 ggaatataat tctgttatac catatggacc ttttatatct attggagcat taataacaat
    52321 cttatctgga aagcaattac ttgaacttta tttttctatg gttatataga tgatagtcaa
    52381 gttaaataaa gttttaattt aaaaaaatga attaaagtat ttaataagga caatattatt
    52441 attaacccta ttactaaagt gctacaaact atggagtata taataataat ttccttattt
    52501 tttgcacatt tgataaataa atctctatgt gttttttgtg atagagaaaa gaaaaattta
    52561 tataatacgt tttttattta cataataact gtagttttat ctgtattaat atatctaaaa
    52621 tttgggatta gtgtagaatg tgtacaatat atggttttaa ttccattttt aataattata
    52681 tccattgtag attactacac aatatatgta tatgatataa caatagttag tggtataata
    52741 gttcaaggta taattttttt ggcctttttc aatatagttc aatttgatta tataaatcat
    52801 atatttggac tattgatagg ctttattata ccttatatta ttgctaaact aacaaaagga
    52861 ttaggctatg gagatgtagg tctctatagc ttatgttgct ttgcattggg aaataattat
    52921 gggttttatg tgatagtttt atcatttatt ttagcgtttt tgttttttat tattttatac
    52981 ataactaaaa tatttaaaga tgtagatata agaaagcaaa ttccttttac accttttatt
    53041 tccttgtcaa caattttaat aatatttaca gagtataata tatttaattt ttattataat
    53101 ttgttataca aatttatata acaggaggta agaaatgtac gtagtagtag ggttaggtaa
    53161 tccaggaaag aagtatgaga agactagaca taacgttgga tttgatgtta tagatattct
    53221 tgctaaagaa tacaatatta gtgttactaa aataaagcat aaagctttga ttggtgaagg
    53281 gagagtaggt actgaaaaag tattattagt taaaccacaa acttatatga atttaagtgg
    53341 agaaacatta atagatatat ataaatatta taaggttgat ttaagtaata tagtagtagt
    53401 atatgatgat atagatttag aagttggaaa gatacgtata agaaaaaaag gaagtggagg
    53461 aactcataat ggcatgaaat ctataactaa gtgcctaggt tcaaatgact ttccaagagt
    53521 gagagtaggt gtatctaaac cagaagctgg tcaagactta gcagactttg tactttctag
    53581 atttagaaaa gaagaatctg ataacataaa tgaagcatta gaaaaagcgg cagatgctat
    53641 tgactcaata ataagagaaa atatagatat gtctatgaac aaatataatg gatagtgaga
    53701 gggagattta aatgaatgat gtttttttat atcctttgca aaattcaaaa gagtataaag
    53761 atataataaa ctgtataaaa aatacaaaag gctcattatt ggttaatgga cttttaccag
    53821 tacaaaaacc tcatatatcg tattctatat ttaatgattt atcacgacaa atgattttta
    53881 taacgagtag tgatttagaa gcaaagaaag tatacgaaga tttaagtttt tatatggaag
    53941 ataaagttga atatttaggt tttcaagata tttattttta tcacttggat gcaaaggaca
    54001 gaaacgaaga agcgaagaaa ttaaaagtat tgttaaaact agcaaataaa gaaaaaatca
    54061 ttttagtaac ttctattgag gcagttttaa gaaaatacat accaaaacaa gttttgctcg
    54121 atagtgtatc tcattataag gtgggagata gcttagactt agaaaagtta actgagaaat
    54181 tagtttcatt gggatatgaa agagtttcaa aaatagaggg gtttggtcaa tttagtataa
    54241 gaggtggaat tattgatgta ttttcacttg aatatacaaa tccaattcgt atggaattat
    54301 ttgatgatga gatagattcc atacgaactt ttgacgtata ttcacaaaaa tcaattgata
    54361 aattgcaaca attctctata actccatcta gggaatttat ttatcccgaa aaaactacag
    54421 atgcattagt taaattaaaa aaagaaacaa ctaaaaatac tgatgaaggt acatttcaaa
    54481 atatagatta tatatcaagt aagacttatt ttgaaggtgt agagaactat atagattata
    54541 tttatccaga agaaaacaaa agtatattta cttatttagc agatgatgca atagtattta
    54601 ttaatgatat aacgagactt aaagaaagat gcgaaaatta tataaatgag tttagagaaa
    54661 attataaatt aaatcttgaa agaggtctgg ctattaaaaa ccaaggtaaa ttgttatatc
    54721 actatacaga tttagagtac ttagtaaaag acaagtctgt ggtattaaac tcgctattgc
    54781 caaagtctat aaataacttt tctataaaat ctataataaa ttttgaaagt agagaagttc
    54841 ctacatttaa tggaaaggta gatttgcttg tagaagaatt aaatcggctg aaatataatg
    54901 gatacaaaat aattttagca acaaatacct tagaaagagc aaataaatta ggaaaagatt
    54961 tattggacaa aggcttagaa acgaccattt ctaaagatag agatattgaa attaaatctt
    55021 cacaagttat aattgtacct gcacacataa acagtggttt tcagtataaa tctataaagt
    55081 ttgttgttat aacagataac gaaatgatag gtgtttataa aagagcgtct aagactagca
    55141 ataaaaaagt taaaaaggga aagaaaatag aatccttttt agatttaagt gttggagact
    55201 atgtagtcca tgaaaatagt ggtgtaggta gatacacagg aattgaacaa attacagtca
    55261 atgctattaa aaaagattat atgaaaatag tatatcaagg tggagataat ctatatgtgc
    55321 caatagacca gatggacaaa gtacaaaaat atattggtgc agaagtagaa aaagttaagt
    55381 taaataagct tggaacaaat gagtggacga aagcaaaagc aaaagttaaa aaagaaattg
    55441 aagatatgac aaaagacttg attgagcttt atgcaaaacg tgaaaaaata caagggtata
    55501 agttttcaaa agatacacct tggcaggcag agtttgaatc gttgtttcca tatcaagaaa
    55561 cagaagacca attaaaggct atagaagaaa ctaaaaaaga tatggaatca agtaaggtaa
    55621 tggataggct agtatgtgga gatgttggtt atggaaaaac agaggtagct attagaagta
    55681 tttttaaagc ttgtatggac caaaaacaag ttgctgtatt ggttccaaca acaatattgg
    55741 cccaacaaca ttataataca ttcaaagaga ggtttgaaaa ttatcctttg agagtagaag
    55801 ttttaagtag gtttaaaaca ccaaaacaac aaaaacagat tattgaagat gctaaaaaag
    55861 gattagtaga tattttaatt ggaacacata gaataatatc caaagatata aatttaccaa
    55921 acttaggtct tgtagtcatt gatgaagaac aaagatttgg agtaaaacat aaagaagctt
    55981 taaagaaaat taaatctaca gtagatgtac ttacactttc agcaactcct ataccaagaa
    56041 cattacatat gtctttaagt ggaataagag acatgagtgt tatagaggaa cctccacaag
    56101 aaagacatcc tgtaataaca tatgttacag agagtaagga aagcgtaatt caagatgaga
    56161 tagagagaga attaagtaga ggtggacagg tattttttgt atacaataga gttgaacaca
    56221 ttgaagaaat ggcaagtatg attcaaaaac tcgtaccaga tgctagagtg gctgttgcac
    56281 atggaagaat gacttctaaa tcattagaaa atataatcct aggattttta aataaagatt
    56341 atgatgtact agtctgtact acaataattg aaactggtat ggacatatca aatgcaaata
    56401 caatgattat atatgatgca gataaaatgg gattggctca actttaccaa ttgagaggta
    56461 gggttggaag aagttcaaga caaggatatg catatctttt gtatgaaaaa gataaaactt
    56521 taagtgagat agcggagaag agattaaaag ctatcagaga atttacagag tttggttctg
    56581 gttttaaaat agcaatgaga gaccttgaaa taagaggagc aggaaatatt ttaggttctc
    56641 aacaacatgg tcatatggca gttataggtt atgatttgta cgttaaaatg cttaatgatg
    56701 caattaaaaa agtcaaaggt gaacctattg tggaggaaat tgatgttgaa atagatttaa
    56761 gtgtaaatgc atacattcca gataattata tcaaagatga gttgattaaa attgaaatgt
    56821 ataagaaaat agcttctatt gaaaacaaag aagacatgtt ggatatacaa gaagaacttg
    56881 aggatagatt ctctgatata cctaaaccag tccagacact tcttacaata gcttatataa
    56941 aatcgttatg taagatatta aaaatagaaa agataagaca attaaaagat gaaatattat
    57001 tagttccaat aacaaagtat agaactaaac agaaaatagg ttataatata gttacagaat
    57061 tagaagaatt attagaaaag atgtgcaagg taaaataact tgtaaattta agaagggatg
    57121 ttttaaattt gaaaaaggta ataacattgg taatagctat gattttggta gtatctgtga
    57181 ctgcttgcag ttctagtaaa ggagaaactg tggcaacagt tgaaggtaca aagatatcat
    57241 cagatgaatt taaaaaaact atagctcttt ataaagattc tatggaacaa acttatggaa
    57301 aagatatatg ggataaggaa gttgaaaagg gtgtaaaata caaggacaag tttaaagatt
    57361 taattcttga ccaacttata actacagaag taatatattc tcaagctaaa aaagataact
    57421 tacttcctaa aaaagaggat gttgaaaaaa gctttaaaga attaaaagac gctatgggta
    57481 aagatgaaaa atataaagaa caacttaaga aattaggtat agatgatgag tttttaagag
    57541 accaacaaga gaaagattta gcaatgcaaa actatcaaag taactttgct aaaaagacta
    57601 aaatatcaga tgaagaaatg aaaaaatact atgatacaca taaagatgaa tttaaaaaag
    57661 atgaggtaga agcttctcat attttattga aaacagtaga tgataataac aagccacttt
    57721 cagataagga aaaagctgaa gctaagaaaa aggctgaaga ggctcttaaa gaagttaaat
    57781 caggtgagga ttttgcaaaa gtagcaaaaa aatattcaca agatacttca gcaagtgatg
    57841 gtggtaaatt aggattcttt tcaaggggtc aaatggttgc tgaatttgaa gatgctgctt
    57901 tttctatgaa aaagggtgaa gtatctgatt tagttgaaac tcaatatgga taccacataa
    57961 ttaaagtgac agacagaata aatgagcaaa catcatttga agatgctaaa gaaactataa
    58021 aagaccaact gttgaaaaat aaatatcaag aacaaataga aaaattaact aaagaagcta
    58081 aggtagaaaa agatgaaaaa gtaataaata aaatcacaat ctaagactta aaaaaagagt
    58141 aatatgctta aaaaagctat atctggataa gatatagctt tttttgtata tttttcttaa
    58201 caatggtaaa aataaactta aagtaattta tggagggatt aaaaaatatg aaagcaacag
    58261 gtatagttag aagaatagat gatcttggaa gggtagttat cccaaaagag ataagaaaga
    58321 cattaagaat tagagaagga gaccctttag agatattcac agcaaaagat ggagaagtca
    58381 tacttaaaaa atactctcca ataggtgaat taaatgaatt ttcgcaagaa tatgctgaaa
    58441 cattagctga agtactagga tatggagtgt tgataacaga cttagattct ataatagctg
    58501 tgtctaagct tcctaaaaaa gattataaag aaaaaagtat aagtgatgag ttagaagcaa
    58561 taataagtga aagaacagta aaatattcaa aagataaaaa cattttacca ttattcaagg
    58621 aagaccaaaa agaatatact agtcaagtta tcatgcctat aattagtgca tctggtgact
    58681 gtataggttc aattgtagtt gtttcaaagg ataaagatac aattgcagaa agtgaagaaa
    58741 aatctttaaa aattgctgct aactttttag gaaaacaagt tcaataattt tatcataaag
    58801 accttttaca tgaaggtctt ttgaagtttt tgtgtaaaat attgaatata gcattaaaaa
    58861 tatggtatat taaagtttgt tatataaaca gtatggaggt tatgttatga acaataacaa
    58921 aaataaagac tcctttctaa aaggagccct tatacttggg ctagcaggtg taatcgtaaa
    58981 aataatgggt ggatttttta ggattcccct tggaaacatg attggttcag aaggaatggg
    59041 atactatcag gctgcttatc ctgtgtatac tctattttta acattagcta ctgctggatt
    59101 tccaacagct gtggcaaaat tggtttcgga aaaagttgca attggaaatt ttaaaggtgc
    59161 aaataagata tttaaggtat cacatacagt tttattcatt accggtataa tatcattttg
    59221 tatattattt tttggagccg actacatagt aacaaacgta atgaaaaatc caggtgcgtt
    59281 atactctatg aaagccattg ctccagcatt actatttgtt cctgcaatgt ctgcatatag
    59341 aggatatttt caagggagac aagatatgac taagattgct gtgtctcaag ttgcagagca
    59401 attttttaga gttgtattag gtcttacttt ggcttacttg cttatgaaga gtctaggtca
    59461 gacttttggt gcagcaggtg ctatatcagg ggctacaata ggttcaatag catctatgct
    59521 ttatttggtg tttgcttata tgctagggag aaaagagcgt agagcagaga tagatgcaag
    59581 ccaaagattt aaagatgaaa gagtgtctta tatttttaaa aagcttttaa ctgttgccat
    59641 tcctataaca ataggagcat cagtaatgcc acttgtaaat atgatagata atgttattgt
    59701 aataagaaga cttatggaag caggctttac atacaaagtg gcaaattcca tgtttggtca
    59761 attaacaggt atggcaatgg ccacaataaa tttaccagca gtcataacaa ctgcaatgag
    59821 tatgagctta gttccagcaa tttctaaagc atatgcatta ggaaataagt caaaagctag
    59881 aaaagatact aagagtgcag ttaaggtaac tttacttata gtattgcctt gtgcgtttgg
    59941 tatggcttct ttagcaatac caataatggg tcttttattt ccacatgaac catcttctgt
    60001 aggaactatt ttgtttactc ttactccatg tgtattattt ttaggattaa tacagacatt
    60061 gactggtata attcagggaa tgggaaaacc aatagtacct gtaattgctt tatgtgttgg
    60121 tatgctatgt aaaattgtaa taagttatac tttaacaggt ataccagata ttaatgtact
    60181 gggttcagca tttggtacag ttacagcata ctttgtggca gccatgatta acttactata
    60241 tgttaaaaaa cacatgaatg taaacttttc taaaaaagaa tttataataa agccatttat
    60301 aacagttatg acaatgttta taatggttaa gttgagttat ggtgctttag ttggattctt
    60361 aggaaacagc atatctacaa taattgcaat atgtgttggt ggaattgtat atgtagtagt
    60421 aatacttgga ataggtggaa ttaaaaaaga agagattcta actatgccaa aaggtgataa
    60481 attatataaa ttgttaaaaa aagttaaact tataagataa tataggaata tatatgcaaa
    60541 taaaggaaat actatacaaa tagtaaatct ccttatttgt ataataatat aaaaataaag
    60601 tgaaatttgc taataggagt gatgttatgg gtaagataag tattgtaggt cttggaccag
    60661 gagactattc tcttataagc caaggtgtgt tagaatcttt aataaatagc cctaaagttt
    60721 tttttagaac agagaaacat ccaataattg ataaacttaa agaaactata caatacactt
    60781 ctttagacta cttttatgaa aaagaggaaa attttgataa tgtttatttg aaaatatctg
    60841 aatttatcat agaagaatca gcaaagggtg acctagtgta tgctgttcct ggtcatccaa
    60901 gagttgcaga gaagactgta agtataatag agagattagc caatgaaaag cacatagcag
    60961 tagaaatatt gccttctatg agctttgtag acgctatgtt taactatttg gctatagacc
    61021 catctgaggg atttaaactg gtagatgctt ttgaaataga aaattcatat atagacttgg
    61081 atacaagtat gataataact caggtatatg ataaatttat agcatctaat gtaaagttaa
    61141 aacttatgga acattatgac tataatcaag aagtatgtat agtaaatgga gctggtgtca
    61201 aagatttaga aagtaaaaag tttataaagc tttgtgaatt agacagaaat gaaaactttt
    61261 ttgactattt aactagctta tatataccca aaagttctaa aaagatgtat aatacagtac
    61321 atgacttaga aataatagtt aatacactta gaagtccatc tggatgtgaa tgggataaaa
    61381 aacaaacaca tcaatcatta aaaaattctg ttatagagga agcatatgaa ctttgtaatg
    61441 caattgataa taatgatata gatgaaatgg tagaagagtt aggtgatgtt cttttacagg
    61501 ttatattcca ttgtcagata ggaaatgagg agggctactt tgatttaaaa gaagtagtaa
    61561 atggcatatg taaaaaatta attcatagac atcctcatat atttagtggt gcaaaattag
    61621 atatgtctaa gtttgagaaa acttgggaag aattaaagaa agaagagaaa ggcgaaagta
    61681 ctataacaga tggccttaga aggataccaa aacatttacc agctcttatg aaggctagta
    61741 aagttcaaca taaagcagca cttgtcggct ttgattggga caatgtagaa gatgtattta
    61801 aaaaaattga agaagaatat caggaattac ttgacgaaca cagggtcggg aatataaaat
    61861 acataaagga agagctaggc gatttattat tttcgatagt aaatctagct agatttttag
    61921 acatagactc aggagaagcc ttgaactgta ctacagaaaa attcataaat agatttgact
    61981 ttatagaaaa aagtgcaatg aacttgaata aaaaattaga agacatgaca cttgaagaga
    62041 tggatgagtt ttggaatcag gctaaaaaac aataaaattg tggaaggaaa tttgtcaaaa
    62101 atctagaact tttatcacaa agatagaagt ctatattata aacattttta ggaggtaaat
    62161 atcgtgaata aagctgaatt agtatcaaag atggcagaaa aaagtggatt aacaaagaag
    62221 gaagcagaag ctgcgttaaa cgcatttatg agttctgttc aagatgcact agtaaataat
    62281 gaaaaagttc aattagttgg atttggaaca tttgagacaa gagaaagagc tgctagacaa
    62341 ggaagaaatc caagagatcc agagcaagtt atagatatac cagcttctaa agcaccagtt
    62401 ttcaaagctg gaaaaggatt aaaggatata ataaatggat aattagaaat cttgtgaaaa
    62461 agtgtggata aatttgccac actttttcta tagaaccaag gaaggtgata attatgagat
    62521 tagataaatt tttaaaagta tctaggatta taaaaagaag aactgttgct aaagatgcat
    62581 gtgataaagg gattgtcact ataaatggaa aagttgctaa atcttcttca gaggtgaata
    62641 ttggagatac attagaaata caatttggag agaagaagat gaagtttaag ataaatgaag
    62701 taaaagagca tgtattaaaa aatgatgcaa aagaaatgta caaaatttta gaataaaatt
    62761 aatagtcctc tagtatatta atagtagtat tattgaaata tttactgggg ggatattatg
    62821 gaacagaaca taactttgaa agatagatca aagctggtta tttcgggagt cgagcacata
    62881 tactctttta atgacaaaag agtagagctc aaaacttctg taggcgagat ggtaattgaa
    62941 ggcgaaaacc tagatatgag caagctaagt atagacgaaa atataattag catagatgga
    63001 actataaatt ctatggtata tgcaaagcct aaaaagccac aagagagttt cttgaaaaag
    63061 gtatttagat agatgatacc ttttactcaa gatgtaagca ttttttatgc tactatttat
    63121 ggtggaatac tcataggggt gttgtttgat ttttatagag ggctaagagg gaattttaaa
    63181 ttcatcaatt attttgctat aatctttgat gtattgtttt ggtttctagc tacggttata
    63241 atattcgtaa caataaacct tacagaattt tttgatttaa gatattatca ttttgtggct
    63301 ttgtttattg gttttatttt atactataac accataagta aaattgtttt atcaattatc
    63361 aataaaataa ttcgttttgt gagaaattct tttaaaaaag ttacacatta catagtcagt
    63421 tttttaaata atttgtatta cgttataatc tattcactac acctactatt tgatattata
    63481 ttttatatac caaacatatt tatagcaaca agaaaaagta taaaaagaaa atcaaataaa
    63541 aaattaaaga acaagaaaaa atcaaaacct aagaagaaaa aaaataaaac taaaaaaagg
    63601 gtgtaggaaa aatgaactta agaaaaaaat tttcaggaca gattattgtt atcagtttat
    63661 ttttaggaat atcaattttt agtatgatga caggatttgt atttgagtat acaaaagcta
    63721 aggaatataa aaaagaaata gcaagtctaa ataaacaatt aaaaaagact gaaatacaaa
    63781 taaacagctt aaagaaagat gaaaaatcat atgaaggaga cttagaggat atagcaagaa
    63841 aaagattgaa tatggtaaaa ccaaatgaaa cagtttatgt agacataaat cgttgattaa
    63901 aacttgctaa taagtttaca gatgtattga ttttaaaatt taagatttaa taaaaaagtc
    63961 attcagttaa ggatggcttt ttgtttttat tgaggaggga atttcataat gaaagtagga
    64021 gctatagata ttgggacaaa ctcaatgaga ttattgatag cagattatag agatgggaat
    64081 tttataaaca gaaaaaaatt tgttaataca actagaattg gttatggtgt ggatagtaaa
    64141 ggatatataa aagaagatgc tatcaaaaga aatataaaag cattaaaaga attttctgat
    64201 aagtgtaatg atgaaaagtg tgaaaaaatt tattgtatgg ggacatctgc tcttagagac
    64261 agtaaaaatg gagattactt tgttaaatta gctaaagaag aaactggaat agatgttgat
    64321 atagttacgg gaatagaaga atcaaatttg ggctttaagg gtgttttaga aggaatacaa
    64381 ggtgatgata ctattattgt tatagatatt ggaggaggtt caacagaatt tattgtaggt
    64441 gattcagaag gaattaaatt taataaaagt gagaatgtag gtgctcttag gatgacagag
    64501 aggtttttga agcacgatat tattgaagat gaagagtttg aagctatgag ttcatttata
    64561 tatgatgaga ttgacaaaac gttaaatcat ataaaagaca gaggattaaa aactcttata
    64621 ggtataggag gtacgattac atcattatca gcaatgaatc aagaattaga gatttactct
    64681 atggaaaaaa tacataatag taaaatacac aaaaaagaaa tagaagaaat tctacaaaaa
    64741 ttaataaaga tgacattaag tgataaaaag aacttaaaag ggctacaaga aaaacgtgcg
    64801 gatattataa ctgctggtgt aaaaatattg aatataataa tggaaaaatt agaaatagaa
    64861 gaaataaccg taagtgaata cgataatttg gaaggcttaa tatgtcaaaa gtcaaaaaaa
    64921 atgtattaat attttttgat ttttaaaacc gattatgaca aaaaaaatta ctcctctttg
    64981 ttacaattct taatataaac aaaagaggag gtttttttat gcaaagaagt gtagcagttg
    65041 tgaagaataa gactgtaaaa ccaaatgtca taaaattaat aagcggatat attgatttta
    65101 ctacggcggc attcgctgtg atgggatttt tacttagtag gtctattata gtagactctg
    65161 tagctccttt aggaattgcc ttttttatat gtgcatcaaa gattgataag tacaagatac
    65221 ctgtattcat atcaacatta ttaggaatat tgttatcatc taatgatttt ggaaatgtag
    65281 caaaatatgc tgtgtgcctt acaatattta tggctatgaa taaaaaatta aaattatcag
    65341 attcaattgc taaggttgca tttataggtg caataatact acttccaatc tccatgggac
    65401 aagctttctt ttcaaatagg tatgtatatg gtcttcttat agcaggagta gaagcaataa
    65461 taatgtttat atctatatat gtgttttctt atgggatagg tttaatggcc aatgtcaaca
    65521 ataggatgtc tgtacggaca gaagaagcca tatcaataag tttactgcta acctttagca
    65581 taatgggaat aggagatata tctctgtttg gaatatcaat aaggaccatt ttatcgaccg
    65641 tattgatatt gctgacctca atagtaggtg gagctaccat gggagcatct agtggtgtaa
    65701 ttattggtgt agcatccatt ttaaataata tgacatcagc tgtttatatg gggatatatt
    65761 ctttttcagg attaataagt ggagcattta ataaaataaa taaatatttc tgtatactag
    65821 gatatattct aagttggaca ataatatacc tatatacttc tggtattact tctaatatga
    65881 tgcaattaag agatatacta ttaggttgtt tgatagtact agtattgcca gagagattat
    65941 ttaataagat tgaaaaatta ataaaaagta atgtggcttc aaatgaaatc gtatacgatt
    66001 atattatgag aagcaaaaac ctaactaata gcagattgaa cagtatttat aaaacttatg
    66061 atgaccttgc agatacattt gataagataa gagaaaaaga caaagtgcta gaccaaagag
    66121 acatagctaa tgtaatagat atgattcata atgatgaatg taaaagttgt agtatgagaa
    66181 gaatgtgctg ggagtcaaga tttaatcata catacactat gatatataac attcttgaaa
    66241 aaattgagga gaaaggggag ttaagtctaa acgatatacc taaaaatttt agaaaggaat
    66301 gtatgaaacc agagtcaata gtgaaaatat caaatcacta ttacaaaatg tttgtattag
    66361 attatgattg gagtgtgaag ttttcagaaa gtagaaagtt aatagcaaat cagataagaa
    66421 gtatttcaaa atccattaaa tccttatctc aagatttaga aggcgacata atgctagata
    66481 tagaaaagga aaaaaatata tatgaacagt tagaaagata tgatataaca gttgataaag
    66541 taagttactt aacaaaaagt aacagtgagt ttgaaatatc aatagaaaag aaaacttgcc
    66601 atgatggatg tatgtgtgaa gataaaattg taaatataat ttcagaccta gtaggggaaa
    66661 atatgtctgt tagaaaaata ggatgtcact gtttaggagg taaatgcaag gcaacattcg
    66721 ttaaatctca aaaatataag gctgttacag aagtttcagc aatgtcaagg gatgggcata
    66781 tcctttgtgg agacaattac acatacatgg agataaatga tggtaaatac atgatggcta
    66841 taagtgatgg tatgggaaag ggtaaaaaag catatgaaga atcttctgcc actattgata
    66901 tactggaaaa aatgatagat gcaaaaatta aagatgagat agtcattgat actataaaca
    66961 atatgttgtt gttaaaatct tcagaagaga tgttttcaac tctggatttg ggaattttag
    67021 atttaaaacg aggttgttta gaaactataa agatgggagc gtgttctact tatataaaaa
    67081 gagaggatgg agaagttgac ttaatatcat catcatcatt acctgtgggt atattatcag
    67141 atgtaaaaat tgatagaaaa aatgtaaaag ttaaggaagg agactatgtt ataatggttt
    67201 ctgatggaat tgtagatgca ggaagaaata acaatttagg agacaattgg ttaatatact
    67261 tcttaaagaa tatagagact acaaatccaa aggaaatttc aaatttaata ttggatagag
    67321 cattagagtt acaagcgtta caaatcgaag atgacatgac tgttttagtt acgaaaatat
    67381 gtacaaaata aggtttacaa gattatgtgt ataagatgtg gataacttgt gtataatatg
    67441 ttaatagact tttgaaaaaa gtatagttat taacaaaaat aacatataaa tcaacaaaat
    67501 ttgttgataa gtatggcaga aatgttaata aaatgtaaaa aaagaaaaaa caaaagctat
    67561 tatcaaaaga gattcatgtt gaaataacta aatttctaag taaagaaaac ctgtgaatat
    67621 gttgattatt atgtggataa ctattaattc gatatttatt tatatagtat gaataattga
    67681 ataatatatc taaaaaaagc catcctatta ttaagtaaac ttattgaaag gatggctttt
    67741 tatgaataga aaattgtgca aagcaataat acctttattt atttctattt tttgcatgtt
    67801 aataataagt ataaaagctg accaaggata tcaaaagaat aatgacagag caattactgt
    67861 catgaataat aatgatactg aagatgatgc tgaaaaaaaa caagaaatag actatgaaaa
    67921 aacatgttgg aatttgcaat ctttgtttaa aagtgatgac caatggaaaa aagaacttaa
    67981 gagttttgat aaagatacta aagagttgaa aaattacata ggtaaagtaa caaaatcgcc
    68041 aacacatttg tcttttgcct tgaacattaa agaaaaactt gatataagac taaataaact
    68101 ttctgcctat gtaaaattaa aacaagatac taataaaaat tcgtataagt acttagatat
    68161 gaatgatagt atgagtaaat cctatgggaa ttatatgggg atttgttcag atttagagtt
    68221 agaaatacta aaattatcaa acaaagatta caagaaaatt atttcaaata aaaatataaa
    68281 taggaaatat ggtgcatatt taagagatat aagaaggaat aaagtacatt atttggatga
    68341 taaatcagaa gatattctaa gcaaagtatc ttcaataagt agtcttccaa gtcaagtgta
    68401 tgaattattt agaaatatgg atagaaaaac taatttaaca ccagctcaat atgcgagtga
    68461 attagagtca tcagatagag aaaatagaaa aaaagcttat caagatgaac ttataactta
    68521 caatgataat ataaatacaa ttgcaggttt aattactggt caagttaaaa agaatatttt
    68581 ttattctcag gaaagaggtt atgagtcttc tttagaaatg tacctggaag ctgataatgt
    68641 agatgaaaaa gtatacaata atttgataag gactgtaaat agtaatatgg acagtctaca
    68701 caaatatata gatttaagaa aaaaagtatt aaaattagat aaggttcatt catatgatat
    68761 gtttgtgcct atggttaagg ctgttgataa taatattaat tatgaaaagg cacaaagtat
    68821 agtatattca gcgttgtcac ctttaggaaa agaatacaat gatgtagtat ataaagcttt
    68881 caatgaaaaa tggatagatg tttattcaca tgaaaataaa gtaagtggtg gatactgctt
    68941 atctgtttat gaaaatcatc catatatact tttaaattat aataattcat taggttcagt
    69001 ttcgacttta tcacatgagc ttggacatgc tgtatatgaa tacttaagtt ctaagaatca
    69061 gaattatttt aattcaaatc cgtctatatt tactcacgaa gttgcatcta caacgaatga
    69121 agcattactt tacgagatgc ttataaaaga agctaaaggc aatgatgaaa aagcttatta
    69181 tataacacag tatttagact tgataaaaga tactctttat acacaaacta tgtatgctga
    69241 atttgaaaaa actatacacg agttagtaga aaaaggaaaa agtgtaaacg cattagtatt
    69301 aaatgatgtt tggggacaac ttcttaaaaa atattatgga caaagctatg aattagacca
    69361 attatctaag gtcggatggg ctagaatccc acatttttat aatagtttct atgtctataa
    69421 atatgctaca ggttgtagtg caggagtaag ttttgcccaa gacatcctaa agaatggttc
    69481 agataactat atgagctttc ttaaaaaggg aagttcagat tatccaataa acttgttaaa
    69541 atcaagtggc ataaatttaa ctaatacaaa acccatagaa aatacaatca aaaaatttga
    69601 tagtttagta gcagaacttg aaaagctatt ataaacatta ttgtaatcca catggtaaat
    69661 atatcgaatt aatgataaaa tatactaaaa gtttaaagtc ctatcaagat aggacttttt
    69721 atttattaat tagtgggaga tgattctatg caagttaaag ttaaaaaggc tgtaatacca
    69781 gcagcaggtt taggaactag atttttgcca gctacaaagg cacaaccaaa agagatgtta
    69841 ccaatagttg ataagccaac tctacaatac ataatagaag aagctgtggc ctcaggaata
    69901 gaggaaatac taataataac aggtagaaat aaaaaatcta ttgaggacca ctttgataaa
    69961 tctgtagaat tggaacttga tttagagaaa aaaggtaaga aagaattgtt ggaggtagta
    70021 caaaacatat ctaacatgat taacatacat tatataagac aaaaagagcc aaaagggttg
    70081 ggagatgcaa tttattgtgc gaggcatttt ataggtgatg agccgtttgc agtaatgtta
    70141 ggggatgata ttgtagataa tgatgtacct tgtctaaaac aactaacaga tgcatatgag
    70201 gaatatagaa ctacaatatt gggtgttcaa aaggtaaatc aagaagatac taataaatat
    70261 gggataatag aagcaaaaaa tatagaaggt agagtttaca aggtaaaaga catggtagaa
    70321 aagccagagt caggaaaagc tccttcaaat attgctattt taggtagata tataataact
    70381 cctgaaatct ttgatattct taaggattta ccaccaggta aaggtggaga ggtacaactt
    70441 acagatgctt taaaaatatt atctaagaaa gaagctatgt atgcatacaa ttttgaaggc
    70501 aagagatatg atgttgggga caagctagga tttttagaag ctactgttga ctttgctcta
    70561 aagaaagaag accttaagga agattttata aaatatttga aacatgtatg tagtgaattt
    70621 gataaaaata acaatgtgtt atacaataat acagatgaaa aaatagattt aattgaagtc
    70681 aatgaagcta gagaacttga aattcaaaaa taattaatga aaggtgatgt atggtggcaa
    70741 aatcaagtca gaaaagaatt aatagaataa tagctgttgg gattgtggga atcctcgtaa
    70801 taacgagtat aacagctgtt ttgagtatga ttgcaactat gtaataagat aaatgacagc
    70861 agttgatata cataaatata aaaaccatat ataacttgat gtagtcaaaa acttacaata
    70921 ttttagttat atatggtttt tagaatttat aaatgtaaaa aaaaattttt ataatagttg
    70981 catattttaa aggaaaatat tattataaga tataaatata gtgataaatt tataaaaacg
    71041 tgctaagatt ggacttgaaa tacagtaata tagtaggtaa taatgtttta aattttattt
    71101 attgaccata atatataaat aatgatatta ttagacttaa ctgtttaaat aaaacttttc
    71161 tttttcatgc cttcaatttc caaaataagt atgtatataa atgaatatat agatgaggag
    71221 gatttttttg attttagatg ataaagtatt agaaggatta ggtagtaaga ccttagttga
    71281 gctacgagag atagctaaag aattaaaaat aaaatcaatt actacatata agaaaaatga
    71341 gttaattgag attataaatt ccaaaagtaa aaatgaggaa aaagtaaacg aagagactaa
    71401 agaaaaaaat gaagatatta aagaagacat aaagaataga aaagaaaata tagagcgtga
    71461 aagtatagaa aaagaagttg aatataagag ccctaccaaa tcatacaaca agaaagaaat
    71521 agatacccaa aatatttccc aaaaccaaga acatagaaat caaagaaatg actataataa
    71581 gacaacgagt gtaaatgata gtaataagtc atcaaatata tctaatagaa tggtcagaaa
    71641 taataataaa aactattata tgcctaaaca agttgatgaa tctaagatag tagatgaatt
    71701 taacacatca aaagaggatg aagtagtagg tgtacttgaa attctgccag atggatttgg
    71761 ttttttaaga ggttcaaatt atttgtctac tgaaggagat gtttacgttt caccatctca
    71821 aataagaaga tttaatatga aaacaggaga caagattaag ggaataacta gacatccaaa
    71881 aagtggagag aaatttagag cacttttata tgttcaaaaa ataaatgatg aaaaccctga
    71941 cacagctata caaagaaatg cgtttgagac attaacacca atatttccag aagaacgact
    72001 tacactggaa actaatagaa atgaaatagc tacaagaatt atagatttaa tttcacctat
    72061 aggaaaagga caaagaggat tgatagtagc acctccaaaa gctgggaaaa cagttctttt
    72121 aaaaagcgtt gcaaatagca tagctaaaaa tcatccaaat gttgaactta tagtactcct
    72181 tatagatgaa agaccagagg aagttactga tatgaaagaa tctattgaag gagacgttat
    72241 atattctact tttgaccaag tatcaagtca tcatgtcaag gttgcagaga tggtgttaaa
    72301 tagagctcaa agattagttg aacatggtaa agatgtagta attttactag atagtataac
    72361 tagattggca agggcatata atcttacaat atctcctaca ggtagaactt tatctggagg
    72421 tattgaccct ggtgcacttc atggacctaa aaagttcttt ggtgcagcaa ggaatattag
    72481 acagggtggt tctttgacaa tattaggaac agcattggtt gaaactggtt ctaggatgga
    72541 tgatgtaata tttgaggaat ttaaaggtac aggaaatatg gagctacatt tagatagaaa
    72601 attagcagaa aaaagaatat tccctgcaat agatatttac aagtctggta caagaagaga
    72661 tgatttattg cttgatgatg aagaaaagac tgctctttgg agattaagaa gagaaatgag
    72721 taataattca gtaatggaaa ttacagataa agtcattgaa cttataaaga gaactaagga
    72781 caataaagag tttgtaaaat caataaagaa tttgtaaaat caataataca aatgcaaata
    72841 tggattatat aaactaatag aaaaatcact tgaatggcat aataagttgt gctataataa
    72901 tgtagttgat aatgtaaaaa gaaagttaat ataattaatt tttttaaata aagagaagag
    72961 gtgactataa tgcaaaagga aatacaacca aaatacaatc cagttgaagt gcgttgtgct
    73021 tgtgggaaca catttgttgc tggttcaact aaggacgaaa taaaagttga aatatgttca
    73081 gagtgccatc cattctatac aggaaaacaa aagaacatag aaaaaggtgg aagaatcgac
    73141 aaattcaaga aaagattcaa aatggactaa tttttataaa agtggagttg gaggaagcca
    73201 actcctattt tattacaaaa aaacattcat attctacttt aaattgtctt tttgtattat
    73261 aataataaat atgtaaaatt gagtattcta aatacaataa aatgaggtga gtggatggca
    73321 aaacaagctg taggtgggca agctgttatt gaaggtgtaa tgatgcagtc aaaagacaaa
    73381 agagcggtag ctgttagaaa aagtgacgga gaaatagcac taaaagaaga tagaataaaa
    73441 agttgggtaa gagataagaa tatagataag ataccttttg ttagaggttc ttttgttatg
    73501 atagatacaa tgattcaagg cataaaaagc ttaaactttt cttcagagtt ttttatggaa
    73561 gaagctgaag aggataaatt tgatttattt ataaagaaaa tttttaaaga taaggcaaat
    73621 gatataatta taatattttc attggtcata gcaatgttac tttctgctgg attattcatt
    73681 tttataccta cattggtagg aggagctttt tctaaagtaa tgcctaatga ttttatgctt
    73741 aatttaatag aaggaatcat aaggatagct atattatttg catatatagt attgatttca
    73801 cgaagtaagg atatagaaag agtctttcaa tatcatggag cagaacataa atctatatat
    73861 tgctatgaaa atgatttaga acttacagta gagaatgcta gaaaatttaa aagattacat
    73921 cctagatgtg gtacaaattt cctatttata gttatggctg tatcaataat attgtttgca
    73981 ttttttggtt ggccaaatcc aattcttaga atatttatga gaattatatg tgtgcctata
    74041 gtagcaggtt tatcttatga ggtaattaga gttcttggga aatatgataa tggatttact
    74101 aaaattattg catatccagg aatgatgttg caatatttta caacaaaaga gcctgatgat
    74161 gagcaattag aagttgcttt ggaagcattg aaagcagtag tagattagag aaaaggatat
    74221 ttgttatgac gataaaagat ataattatta aatattcaga taaactaaaa gatataagtg
    74281 atactccaag attagataca gagttattgt tacaaaaaac attgggtgtt gatagattat
    74341 atattcactt aaatctgaat aaagagctaa ctgaagaaca aaaaacaaaa tttatgggtt
    74401 ttgcagaaga aagattaaat ggaagaccaa tagcatatat agttgaaaat agggagttta
    74461 tgggattaga tttttttgtt aaggaaggcg tattgattcc aagaccagat acagaaactt
    74521 tagtagaaga aataattgaa atatgtagag aaaaaaaaga tgtaagtata ttagatatag
    74581 gaactggttc tggagctatt acaataagtt tagcaaagta cattgaaaat tctaaaatca
    74641 tgtcttttga tatatcagag acagcattag aaatagctaa aaaaaatgct attataaatg
    74701 aagttggtga aaaaataaag tatattaatt ctgatttatt tacagcaata agtgatagta
    74761 acataaaatt cgatatcata gtttcaaatc caccatatat taaaaaacaa gatatagaaa
    74821 ctctgcacaa acaagttaaa gattatgaac catataatgc tcttgaaggt ggagaagatg
    74881 gattagactt ttatagaaga ataacagaac aaggtaagaa atatttaaat aagtgtggaa
    74941 tattagcata tgaagttggt cataatcaag ctgaagatgt aataaatatt atgaaaagta
    75001 atggatataa aaaaatatac acaaagaagg atattcaagg cattgataga gttgttatag
    75061 gttacaatat atgatataat caacaattga tatgttacat ttaatcgagg tgaaagtatg
    75121 ttaaaaaaat tagaggtatt ggaagataca tataaagact taagtgaaaa aataggtgat
    75181 ccggatgtaa taaatgatca aaaagtttgg cagaaatata taaaagaaca tgctgacttg
    75241 gaacctattg ttatgaaata cagagagtat aaaagcgttt tagatagtat aaaagaatca
    75301 aaagaaattt tacaagaaga gtcagatgaa gaattaagag aattagctaa aatggagtta
    75361 gctgagatgg aagaaaaagt agcacctctg gaggaagaaa taaaaatact attattgcct
    75421 aaagacccta atgatgataa gaacgttata gttgaaatta gaggtggagc tggaggagat
    75481 gaagcagctc tatttgctgg tgatttattt agaatgtact caaggtatgc tgaaagaaga
    75541 agatggaaaa tagaattatt gagtgcaagt gatactggag ttggtggata taaagaagta
    75601 tcttttatga taaaaggtaa aggtgcttat tcaagattaa agtatgaatc tggagttcat
    75661 agagttcaaa gaataccatc aactgaatct ggtggaagaa tacacacatc aacttctact
    75721 gttgcagtat taccagaagt tgaagatgta gaggttgaaa taaatccaaa tgatttaaga
    75781 atagatgttt tccgttcttc aggtaatgga ggacaaagtg tcaatactac tgactctgct
    75841 gttagggtaa cacatatacc tacaggtgaa gtagtatctt gtcaagatgg aaaatcacaa
    75901 ttaaaaaata aagagcaagc tttaaaaata ttaaaagcta gactttacga taaagcattg
    75961 gcagaacaac acaaagatat agcagcagaa agaaaaagcc aagtcggaac aggagacagg
    76021 tcagaaagaa taagaacata taatttccct caaggtagaa taagtgacca tagaataaat
    76081 ttaactttat ataagttaga tgcattctta gatggagata tagatgaaat gatagatgct
    76141 ttaattactg ttgaccaaac agaaaaaatg actgcaatat aagtaatgtt ttaaagaagc
    76201 tgtttcttcc tagaaattat tttctatttt gaaacagcta ttttgcattt taggtcatgt
    76261 tatcatattc tattgtatat aattgttata tacaagtata ggagggttat atgatactaa
    76321 aagtaacaat aattgggctt ttggcaggtg ttatagggac aggattagga ggagtaatat
    76381 cagccatttt taaaagagag gtcgataaat atctaagttt ttttatggga ttatctggtg
    76441 gaataatgtt ggctgtagtg gtgtttgatt taatgaaaga atccatggac aaaatgggga
    76501 taatcaatac agttatattt acgtttgttg gagctctcat aactatgtac ataaaaacaa
    76561 aattagatgt gtctggaaat atggcatctg gatatcttat attcataagt atattactac
    76621 ataatttacc agaaggacta gccattggtt cttcttttat gtcaactgaa agtttaggta
    76681 ttacacttgc tatagttata ggtctacata atataccaga agggttagct atggcattag
    76741 gcttagtttg caataaaatg aaactaagta aagttatttt gtttactgta atagctggat
    76801 tacctatggg tctaggaagt tttttaggtg tttattttgg aggagtattt acttctctta
    76861 taggagtatt tcttgctaca gcaggaggta ctatgatgta tgttgtattg gaagaaattt
    76921 ttccacattc aaaaagtgtg tattgtataa ttggtttctt gttaggtaca atgattgtaa
    76981 attatatata aaattaaaat gaaagcaggc atacaaaaga tgaaaactat tataagtaat
    77041 attgatataa ataatattga ttatgaggaa ataaaaatac aagcaaaact tcttagagaa
    77101 ggtaaaacag ttatttttcc aactgagaca gtatatgggt tgggtgcaaa tgcattagat
    77161 gaaaatgcag taaagaagat ttatgaagct aaaggaagac ctagtgacaa tccattgata
    77221 gtccatatat atgaaaaaga agaagtatat gacttagcca aagatataag tgataaagct
    77281 aaacttgtta tagaaaagct ttggccagga cctataacaa ttatattaaa taaaaaagat
    77341 ataattccat acaaaactag tggagggctt gatacagttg caataaggat gccttctaat
    77401 gttattgcca gggcaataat aaaagaagct ggtataccta ttgcagctcc ttctgcaaat
    77461 atctcaggtc gcccatctcc aacaaaagca aaacatgtat atgaagagat gaatggaaga
    77521 gtggatggaa tagttttagg aggagacagt aattttggat tggagtcaac tgtattggat
    77581 ttaacagaag agactcctat gatactgaga ccaggaagta taactaaaga agttttagag
    77641 gaacttcttg gagaagtaaa gcttgaccca tcattaagta aaaaagaaga taatcaaaaa
    77701 gctaaagctc ctggaatgaa atataaacat tattctccaa atgcagatgt atatataata
    77761 tctggaaaaa gagaaaatgt agcaacaaag attaatgata tgataaaatc taatagagac
    77821 aaaggtctaa agacaggtgt aatgtgtatt agtagaaacc gagagtttta tgatggagaa
    77881 gtaatcgatt taggaaactc tcttgaagaa gttgcaagta atctgtttga tgctcttata
    77941 gaaatggaca aaaagggtgt tgatgtcata tattcagaag agttccctaa gactggagtt
    78001 ggacaagcaa ttatgaatag actactgaag tcagcaggat acaaagtgat aaaggcttaa
    78061 gagggagttg taaaatatga atatacttat tgtgtgtaca ggtaatactt gtagaagtcc
    78121 tatggctgag gctatactaa ggaaagcaat taaagaatct ggaagaagta ttgaagaata
    78181 ttctatatca tcagcaggta tatctacagc aaatggaatg ggtgcttctg aaaattctat
    78241 agaagtacta aaagaaatcg gtatagactt atcaaatcat agaagtaaag taattactaa
    78301 aaaattaatt gatgaatcag atataatact aacaatgact aaatctcata aagaaatttt
    78361 agtacaagca gttccaaaat gcaaagaaaa agtgtatact tttaaagggt ttgcaaataa
    78421 aaatgaggaa gatatatctg acccatttgg tggaaatttg gatatttata gaagcactat
    78481 gagagaaata atgtattctg tcaacgaaat agtaaaaaaa atatgaaacg gaggataaac
    78541 aaatgaagat aggattaggc tgtgaccatg gaggatataa tttaaaaaaa gaaataataa
    78601 gctatttaga aagtaaaggc atagaatgtg tagattatgg aactaataat gctacagatt
    78661 ctgttgatta tcctgtttat ggagaaatag ttgcaaattc agttataaat aaagaagtag
    78721 attatggaat attatgttgt ggtacaggga taggaatatc tttagctgct aataaggttc
    78781 ctgggataag atgtgcagtt gtatcagatg tattttctgc aaaaatgtca aaagcacata
    78841 atgatgcaaa tatgttatca ttaggcgaaa gagttttagg aaaaggtcta gcacttgaga
    78901 tagttgaagc atggattaat acggattttg aaggtgatag acatgctaga agagtaaaca
    78961 tgattaaatc aatagaagaa aaacataata aataataaaa attacagttt tatcaggagg
    79021 aattatcaaa atgagcaaag tggtagagac aaaccatcca ttaatacaac ataaattaac
    79081 tttaatgaga gataaaaata ctggttctaa agactttaga gagcttttaa ctgaaattgc
    79141 aatgttaatg gggtatgaaa taacaaaaga tataccatta aaagatgtag aaatagaaac
    79201 tcctattcaa aaaacatcat ctaaagtagt tgcaggtaaa aaattagcaa taattccaat
    79261 tttaagagca ggtcttggaa tggtagatgg attagtgagc ttaatgccag cagcaaaagt
    79321 tggacatgta ggactatata gagacccaga aacattaaaa ccagttgaat attattgtaa
    79381 gcttcctcaa gacataggag aaagagatat aatagtagtt gaccctatgc ttgcaacagg
    79441 gggttctgct gtagcagcta tagatttact taagtctaaa ggagctaaaa gtataaaatt
    79501 agctaattta gtagctgcac cagaaggtat agcagaagtg caaaaatatc atgatgatgt
    79561 tgatatatat gttgcatcag ttgacgaaag attaaatgaa catggatata taattcctgg
    79621 tcttggtgat gctggagata gattgtttgg aactaaataa aaataaataa ctataaatat
    79681 ttattaggga ctttcttata tagtgtatat aattttatgt aagaaggttc ttttttatat
    79741 attttttctc aaaataggaa ttattgaatt gataaatttc tcgaattgag aataaaaagt
    79801 ttttaccaat taaaaaagat tgcttatttt acaaggtttt atagaatagt agtctatttt
    79861 aatgtggcat gttagttgct tacgattaag attataggta ttaagtgtat tagttaaatt
    79921 gagaattgaa tattaataat attattggga gtggtaatac atgaagaatt gtatagtagt
    79981 aagaggggct ggagatttag caacagcagt tattcataaa ttacacaaca gtggttttaa
    80041 agtagttgcg ttagaaatag aagagccatt agctataaga aggcaaattt ctttttgtga
    80101 ggctgtttat gaaaaaaaag taactgttga aggtgtagaa tgtatatttt gcaatactga
    80161 aaaagaaata gaagaagttt tatctcaaca taaagtagcc ttgattatag acccaaaagg
    80221 agaaaaatta tctaaattaa atccaatcgt tttggttgat ggaatactcg ctaagaaaaa
    80281 cttaggtaca actaaagata tggcaccact tacaatagct ttaggtcctg gattttgtgc
    80341 aggagaagat gtagatgttg ttatagagac aatgagaggt cataatctag gaagaataat
    80401 aactaatggt agagcagaaa aaaatacagg agtaccagga gcaataaaag gtttttctaa
    80461 agagagagtt atgcattcac agtatgatgg cataatggaa aatgtatgta agataggtga
    80521 tatagttgaa aagggagacc tactttgcta tattaataat tatgaaaaaa aacatgaagt
    80581 tagagcaaca atatctggag tccttagagg tttattaaag gatggagcaa aggtaaacaa
    80641 aaatttaaaa atactagaca tagaccctag aaaagaagaa gttaagaatg cttttacaat
    80701 atcagataaa gctagatgta tagctggagg ggttttagaa gccatactaa acaatgggat
    80761 ttatccccaa aattaattta tattagataa agctattaat attttattaa gatgatataa
    80821 taaatttaat agattaaaga gagcatatga cgggtattta aaatttaaat ggtaaaaatg
    80881 ctcttttttt attggacatt caattaacat gtgtatataa tataaaaata agtatttatt
    80941 taggttgaaa tctaataaat atataatacc agtacataag caaagaggag aaaagtaaat
    81001 tatgagacca tcatgggatg aatacttcat ggaaattgca gaagtagtga aaaagcgttc
    81061 aacttgtatt agaagacaag taggagctgt aattgtaaga gacaaacaaa tattaacaac
    81121 tggatataat ggttctccga gaaatcttga acactgtgaa aatattggat gtaagaggca
    81181 ggaattaaat attccctcag gagaaaggca tgaattatgc agagcattac atgctgaaca
    81241 aaatgcgata atacaagctg ctcataatgg tattagtgta gatggggcaa ctttgtatgt
    81301 tactacaaga ccttgtgttt tgtgtgcaaa aatgtgcata aatgcaggta tattgaaaat
    81361 tgtttatgaa ggtgattatc cagatgatat gtctacagaa ttattaaaag aagcaggaat
    81421 agaactcata aaattttagt ggataaaatt tatatgacaa taaatgtcaa attatgacac
    81481 tgaaatacaa tggtatcaaa tgattaaaag aaagtatttg aaaaatcatc agattagtag
    81541 taagatatat tttataatta aataaattta tgagatagat taattacatg ttatttattt
    81601 tataataatg agggatacta tttatgagta aaagaaatac acatacagaa attgcaaagt
    81661 tgtttagttt aataagccaa ataggattga tgattgtaat atcaatatta ggatgtactt
    81721 tcttaggaaa atttttagat agtaaattga atactactcc agttctgaca ataatatttt
    81781 tattgttggg tgttggaggt gcttttagtg gtgtttataa aactctaata gtatatacac
    81841 gaaggaagtg atatattgga tataaaatta cttaaccagg taaggtcagt aacaaaaggt
    81901 atagtaatat ttgatgtagt tttaattgtg ctaatgttga taacatcaac attaagtaaa
    81961 ccagtattat taggacttat atttggctct ataatagcta tgttaaattt tagattattg
    82021 gcgatatcac tggaaaaatc agtgacattt cctgctggga aggcacaagc ttatgcatca
    82081 gcacaatatg ctgttagatt atttataatg gcagttgttc taattgcatc agctacagta
    82141 ccacatttaa atataatcgg aacagcattg ggattattga gcacaaagtt tgtcatatta
    82201 tcaaaaaact ttataaataa attaaagagg aaggaggcat aagtatgaat caagcgcatt
    82261 attatctcat aggaaacttt aagattagtg aaacaatact agtaagttgg ggaataatgg
    82321 cctttttagc gatagcatct tattttttga ctagaaactt aaaaaaagtt ccaactagta
    82381 aagttcaaat attcttagaa tttgcagtag gtggtcttgc taaaatggtt acagatgtta
    82441 tgggtaaaaa tacagtaaaa agaatgccat atatgatacc atacatagga agcttgtttt
    82501 tatttttcgc atgttcaaat ttaagcccat tacttggatt aaggtcacca acaaccgact
    82561 tagatacaac tgctgcatgg gcaatgatta cattttttat gatttatttt gcaggagtta
    82621 aatttaaggg gttatcatac tttaaagaat tggctcaacc acttgccata atgttaccaa
    82681 tcaatattat aggtgagtta gctagaccaa tatcattaag tttccgtcca tttgggaata
    82741 ttttaggtgg aacaataata atgggtctgt tttatcaact tttaggtttt atttctagtt
    82801 taataccagg attatcaata ccaattggag aaatattaat accagtccca ttacacttgt
    82861 actttgactt atttgcagga ttgttacaag catatatatt tataatgtta acaatggtat
    82921 ttatatcaag tgcaggagag ttagattaag aaatcaactt atattaagat aaaaataaaa
    82981 taatttaaaa aattaaagtt ttaaggagga aataattatg gaaacagcaa tagtagcggc
    83041 agcatcagca ataggagcag ggatagcagt tgcaacaggt ataggtgcag gtataggtca
    83101 aggtatagca gcagctaaag ctgcagaagc agtaggaaac cagccagaag ctaaaggtga
    83161 tataacatca actttattac taggagttgc tatagcagag tcttcagcaa tatatggttt
    83221 ggttatatca ataatacttc tattcgtaaa tccattcttt aaatacttag gaatgtagat
    83281 ttagtcctta aatattttga gataggttta taggtaaatc atctcaaact tataatcatg
    83341 agatgaactt tatcatctcg tgattataag tagttatgat ttatggaaag gaggataatt
    83401 atggaaaaag cactagtagg tataacgtgg gaatttgtgt tccaaattgt taatactttt
    83461 ataatatttt tacttctgag aaagctttta ttcaagccag tattaaatat aattgaatca
    83521 agagaaaatg atattaaaag tgatttggta gaaggcgaaa aagcaaaaaa tgaaggttta
    83581 gctctgaaaa aagaatatga gtcaaaaatc aattttgcca aagatgaagg tcaagaaatc
    83641 ataaaacaag caactataag agcagagcag aaatcagatg atatagtaaa tactgcaaag
    83701 aaagatgctc ttgatataaa agaaaaagca aacaaagata tagaacaaga aagacaaaag
    83761 gttataaatg aaatcaaaaa tgatatatct aacatagcac tacttgcagc atctaaagtt
    83821 attgaaaaag atttagataa atctaaacat gaagaattga tagaaaactt tataaaagag
    83881 gtaggggaag ctaaatgata aatgtaatag caaatagata tgccgaagcc ctatttcaat
    83941 taggagaaga agaaaattca actgatgtct tattcaaaga actagaaaaa gtagtagata
    84001 tgatgactaa agttagtaaa gatttctaca aagttttaaa atcaccatta gtttcaaaat
    84061 cagaaaagaa aaacttggta gaaattattt ttagtaaaga agtaagttct aacataaaaa
    84121 actttttaaa agttttagta gataaagata gaatatcata tttagaagat atcgaattag
    84181 cttataaaga attattaaat aagaaaaaca atgtaattga tggagtagca ataagtgcta
    84241 ttccaatgag tgaaacagat attaaagaac ttgaagtcaa actttcaaat aaatacaaca
    84301 aaaatgttac tatagaaaat gttgttgaca agactatact agggggagtt ctagttagaa
    84361 ttggaaatga acaaatagat ggcactgtga aaactcgtct tgataagatg aaagaaaagc
    84421 tatctgaagt aatatcttaa gaatggcggt gaacccatga acttaaaacc tgaagaaata
    84481 agttctataa ttaaacagca aataaaaaat tatgagaata aagttgagtt gacagataca
    84541 ggtagtgttt taacagttgg ggatggtata gcgagtgtat atggattaga aaaagctatg
    84601 tctggtgagt tgctagagtt cccaggtgaa atatatggta tggcacttaa cttggaagaa
    84661 gaagtagttg gagctgttat ccttggagat gacagtgaaa taaaagaagg cgatatagtt
    84721 aagagaactg gaagaatagt tgaagttcca gttggagaag ctttaatagg tagagttgta
    84781 aactcactag gtcagccaat agatggaaaa ggacctatag cgtacacaaa aactagacca
    84841 gttgaatctg aggcacctgg tataatagat agaaggtctg tttatgaacc attacaaaca
    84901 ggaatcaaat caatagattc aatgatacca attggtagag gtcaaagaga gttaataata
    84961 ggtgacagac aaactggtaa aacatctata gttattgaca ctatactaaa tcaaaaagga
    85021 aaagatgtta tctgtatata tgtagcaatt ggacaaaaac gttctactat agctcaatta
    85081 gttagctctt tagaaaaagg tggagctttg gattatacaa tagtagtttc agcaacagca
    85141 tctgaatcag caccacttca atatatagca ccatatgctg gagcagctat gggtgaagaa
    85201 tttatgtaca atgggaaaca tgtacttata gtgtatgatg atttaagtaa acaagctgtt
    85261 gcatatagag aaatgtcatt gttacttaga agaccaccag gacgtgaggc atatcctgga
    85321 gatgtattct atttacattc aagattactt gaaagagcag ctaagttatc tgatgaattg
    85381 ggtggaggtt caatgactgc cttgcctata atagaaactc aagctggtga cgtttctgca
    85441 tatataccaa caaatgttat atctataaca gatggtcaaa tatacttaca accagagtta
    85501 ttctattcag gtgtaagacc agcagttgac cctggtatat cagtatcaag ggttggtggt
    85561 tctgcgcaaa ttaaagcaat gaaaaaagtt gcaggaacat taaaacttgc atattcacaa
    85621 tatagagaac ttgcagcatt ctcacagttt ggttctgact tagatgaaga tactaaaaag
    85681 agacttgctc aaggtgaaag aatcgttgag atattaaaac aaggtgagca tcaaccaata
    85741 aaagttgaaa atcaagttat gataatatat gctgttataa ataatcattt agaggatatt
    85801 ccgatagata atatagctag atttgaatca gaattgtatg catttgtaga taataattat
    85861 ccggaaatat caagaaaaat attaggtgga gaagacttca ctcatgattt aacagatgca
    85921 ataaatgaat ttaaagaaaa gtttgttgtt gaagtataat cctttttaaa aaaggaggta
    85981 aattaattgg caggagctgg aatcaaagca atcaaaacac gtatgggaac tgttgaaagt
    86041 acaaagcaaa taactaaagc aatggaatta gttgcatctt ctaagcttag aaaagcaaaa
    86101 gaaaaggctg aagattcaag agaatatttt aatactttat acaatacagt aaaagatatt
    86161 gcccaaacaa cacgtggaat tagaaatgaa tttttaaaag aaagagaagt aaaaaataaa
    86221 tgctatgtag tagtagctgg agacagagga cttgcaggtg gatacaattc taatgtatta
    86281 aaggaatctg tctctcatat gaaaggtaaa aaggaaacag tgattactgt tggaaagaaa
    86341 gcacatgaat ttttttctaa aagaaactac aatatagcaa aagatataaa tagtgttgaa
    86401 gcttgtggat atgaagatgc gacagaaatt tcacaaacta ttattgacct gtataaaaaa
    86461 ggtgaagtag atgaagttta tattgcttat acaaaattta aatctgcttt atcacaagaa
    86521 gttgaaattt tgaaattgct tccattagtc tttgaaaaag atacagacga acaaggaatg
    86581 gcagtaaaag aagaaaaaca aaatagatca aaagtacaat atataccatc agcagaagca
    86641 gttttaagtt atattgtacc tcagtttata tcaggtacag tatatggtgg aattttggaa
    86701 tcttttgcat cagagcaagg tgctagaaga actgcaatgg aatcagccac agacaatgcg
    86761 aatgaaatgc tatctaattt agagttaagt tataacagag caagacagtc agctgtaact
    86821 caagaaataa cagagatagt tggtggagtt gaagctctaa aatagggagg ttaggaaatg
    86881 gcaaatgtag gtaaagtagt acagattgta ggagctgtac tagatgttaa gtttgatagt
    86941 gaacaaagcc tacctaactt attaaatgcg ttagtaataa agttaggaga taaagaaata
    87001 gttgcagaag ttgctcaaca tataggtgat gatactgtaa gatgtatagc tatgagtgca
    87061 acagacggac ttgtaagagg tatggaagtt gtagatacag gagggccaat aagtgttcct
    87121 gttggagatg aaactttagg tagaatattc aatgttcttg gaaaaccagt tgatgggaaa
    87181 ccagctccaa aatctgcacc taaattacct atacatagac cagcaccggc gtatgatgaa
    87241 ctagaaacta cagcagagat actagaaact ggtattaagg tagttgactt actagctcca
    87301 tatctaaaag gtggaaaaat aggtctattt ggaggagcag gagtaggaaa gacagttcta
    87361 atacaagagc ttataaacaa tattgctaag caacatggtg gtatttctgt attttcagga
    87421 gtaggagaaa gaacaagaga aggtaacgac ctttatggcg aaatgagtga gtctggagtt
    87481 ataaataaaa cagctctagt atttggtcaa atgaatgaac cacctggagc gagaatgaga
    87541 gttgctttaa ctggacttac aatggcagaa cattttagag atgagcaagg acaagacgtt
    87601 ttacttttcg ttgataatat attccgtttc acacaagctg gttcagaagt ttcagcactt
    87661 ctaggacgta tgccatcagc tgttggttat cagccaacat tagctactga aatgggtgca
    87721 cttcaagaga gaataacatc aactaagaaa ggttcaataa catctgttca agcagtatat
    87781 gtaccagcag atgacttaac tgacccagca ccagctacaa cattctctca cttagatgca
    87841 aaaacagttt tatcaagaca aatatcatca ctgggtatat atccagcagt tgaccctctt
    87901 gaatctacat caaggattct tgaccctagt atagtaggaa aagaacatta tgaagtagct
    87961 agaggtgtac aatcaatact tcaaagatat aaagaacttc aagatataat tgctatactt
    88021 ggtatggatg aattatctga tgaagataag ttaatagttg cacgtgctag aaagatacaa
    88081 agattcttat ctcaatcatt cacagttgct gagcaattta caggaaatcc aggtcaatat
    88141 gttcctgtta aagagactgt aagaggattt aaagaaattc ttgaagggaa acatgatgac
    88201 ttaccagagt cagcattctt atttgtagga acaatagaag acgctgttag aaaagcgaag
    88261 ggaagtatgt agtcatggcc agtgaatttt cattgaaagt tgtaactcca agtaatactt
    88321 tttatgatgg agatgttgaa atgatagtag ttagaactac aaaaggagac aaaggggtgt
    88381 tgaaaggtca tataccattt gtttcaggta tacctgtagg aactttaaag ataaaaaaag
    88441 agggaagttt taaagaggcg aaaatagcag aaggattcat taatgtaact caagataaaa
    88501 ctgtcatatt gacagaatct gctgagtgga tttaataaat taatttagag tataaaaagt
    88561 cattttgacc aaaaaaactt ttgggtaaaa tggctttttt gtgttttggt gttaataaaa
    88621 taacgataaa attgtaagtt tttagtgata ataaattcac aaaatgttta aatttactgc
    88681 caaattatgt tgtaattaat aagataaaga agatttagat agcttttatg taagtgaaaa
    88741 agtcttcata taagaaatac atataaaatt tttataaaat ttaaaaaatt tgcttagttg
    88801 tgtagtataa taaataatat aatagatttg tatataatat tcattacaaa taattttaaa
    88861 agttacagtt ttattataat gattattaaa ttaagataag taacataaac taaataataa
    88921 tgtgtattat cgatagtaaa tttataaatt cattattaat tattgaaaga agtattataa
    88981 attttctgga ggaacaatga atatatttga tattggcgta gatataattg aaattgatag
    89041 aataagaaag gctgtagaca aaaataatag gtttttggag aagatattta cagatagaga
    89101 aatagagtat tttaattcta agaattttaa agcagaaagt atagcaggta atttcgcagc
    89161 caaggaagct ataagtaaat ctataggtac aggaattaga gtgtttaatt ttaaagatat
    89221 agaagttctc agagatgaaa tgggaaaacc aatagtaaaa acttataata atctagcaaa
    89281 aatgtgcata gattataatg ttttagaaat aaaagtttca atatcacatt caaaagatta
    89341 tgctatagca aatgcgataa ccataattaa ggactaagga gtgattacat tatgatggat
    89401 aaaacagcaa aagaaataat gacaacagat gtaatagtag caaaacaaga tgatagtata
    89461 gcagatgtag ctaatatgct aattgcagaa aaaataggag gtctgccagt tgtagattca
    89521 gagaatagag ttgttggaat aatttctgaa acagatattc ttaaaaaaga aaaatatata
    89581 gaagcacctc tctatataaa tctattacaa ggattgattt tcttagatga cttaaaaaaa
    89641 gttgaaaaag atataaaaca agtagctgct tataaggttg gagaacttat gtctaaagat
    89701 ataataaagg ttcatgaaga tgataagttt gatgatgtag ctaatgtaat gattaaaaaa
    89761 tcaataaaca gagttcctgt agtagatgat gacaacaaac ttaaaggtat aatttgtaga
    89821 tatgatataa taaaagcttt atacaatgaa taaactgaag taggaggtgt gatgtgagaa
    89881 aaaagtggac catagtatgt attatgttct tggcactggt tataattgta ataggatgcc
    89941 aaaaacgaca gtccacaaaa gaagaagtat acaaagattt tcaaaagcag atttctgata
    90001 tgaattatta cagttgtaaa gctgaagtag aagtagttgg aaataaaagt ccacacaatt
    90061 atgttttaat tcatacttat aaaaaaaccg ataactataa attagaagta atttccccaa
    90121 aacatttaaa agggaaaagt atagaatatc aaggtgataa aatattagtt aaaaatccaa
    90181 agattagtga tgtagtggag ttacctaata caggaaaaaa taatcaatat ctttttgtag
    90241 gagactttat aaaaaactat cttcaaaatg aggagatgaa agtaaagtta tccaaaggac
    90301 atttggtttt agagactttt attcctgggg ataataaata ttttaacaag caagtattat
    90361 atgtaaatgc tgacacaaaa aatcctgaaa aaatggaagt gttagataaa gagggagtgc
    90421 caagatttac agtaaaatac aaagattttg aatacagaaa ctaaggggga ctaaagacat
    90481 gcaaaaaata acagtgccta catgggcaga gataaatcta gataacttaa gatttaactt
    90541 aaataatatt aaaaatttat tagaagaaga tattaagatt tgtggagtaa taaaagctga
    90601 tgcatatgga catggtgcag tagaagttgc aaaattgcta gaaaaagaaa aagtagatta
    90661 cttagcagta gcaagaactg ctgaaggaat tgaacttaga caaaatggca taacacttcc
    90721 tattttgaac ttgggatata ctccagacga agcttttgaa gattctataa aaaataaaat
    90781 aactatgaca gtttattctt tagaaacagc acaaaagata aatgaaattg caaaatcttt
    90841 aggagaaaaa gcctgtgttc atgttaaaat agactcaggg atgactagaa taggtttcca
    90901 acctaatgag gagtcagtac aggaaataat agaattaaat aaattagaat atatagattt
    90961 agaaggtatg tttactcatt ttgctacagc tgatgaagta agtaaagagt acacttataa
    91021 acaagctaat aattataaat ttatgtctga taaattagat gaggctggtg taaaaatagc
    91081 tataaaacat gtatcaaaca gtgcagctat tatggattgc cctgatttaa gattaaatat
    91141 ggtaagagca ggaataatat tatatggtca ttatccatct gatgatgtat ttaaagatag
    91201 attagaatta agaccagcca tgaaattaaa atcaaaaatc ggacatataa aacaagttga
    91261 accaggtgta ggaataagtt atggactaaa atacacaact acaggtaaag aaacaatagc
    91321 tacagttcca ataggatacg cagatggatt tactagaatc caaaaaaatc caaaggttct
    91381 tattaaggga gaagtgtttg atgtagttgg tagaatatgt atggatcaaa taatggttag
    91441 aattgacaaa gatatagaca taaaagttgg agatgaggtt atactatttg gagaaggcga
    91501 agttacagct gagcgtatag ctaaagactt aggaactata aactatgaag tgttatgtat
    91561 gatatcaaga agagttgacc gtgtttatat ggaaaataat gagcttgtac aaataaacag
    91621 ttatttgcta aaataaaacc atgatattat aatctgggag gcgattttgt gtacgataag
    91681 agtaaagaaa aaatagaagt tactttacct gactctctga tttctgaagt tgatagtata
    91741 gttcagatgg agaacagtaa cagagaagat tttgcaaaag ctgcttttca gttctatata
    91801 actcagaaaa agaaaattca tattaaagaa tctatgaaaa cgggttatag agaaatgggt
    91861 caaattaatc tgtcactagc tgaattaggt atgacagttg aagaagtatc ttctgatgat
    91921 aaaaatgaag ggaagattgc ccaaggtgag tactaattgt gaaataaagc gtggtgattt
    91981 atattacgct gatttaagtc cagttgttgg ttcagagcag ggaggcgtta gacctgttct
    92041 gataatacaa aatgatgtag gtaataaata tagtcctaca gttatagtat cagctataac
    92101 atctcagatt aataaagcca agttacctac tcatgtagag ataagttcca atgaatatgg
    92161 gcttaataaa gactcagtaa ttcttttaga gcaaattaga actatcgata aaaagagact
    92221 gagggaaaaa attggttgtc tagatgaaaa tatgatgata aaagtagatg atggacttca
    92281 aataagttta ggattgttta ctttttaaag agggatttgt cttttattag acaatccctt
    92341 ttttctttta aatatctctt aaggtttaat tttaatgtac tatgttaata aaattaaaaa
    92401 taacgcaaaa aaatagcata aaagtgatat aataatatgg aattgatata aaattacgaa
    92461 ctcaagggag gtaattgcat gagagaccat aaaggattaa atgagattgc gcgtatcata
    92521 agaagagata tagtttcaat gatacataga gccaaatctg gacatccagg agggtcatta
    92581 tcagtagttg aaatacttac tgcgttatac tttgatgaaa tgaatgtgga ttcttcaaat
    92641 cctaaaatgg aggatagaga tagatttgta ttatcaaaag gacatgctgc accagcatta
    92701 tatgctacat tggctgaaaa aggttatttt gataaggaag aactgaatgg attaaggaag
    92761 ataggaagga tgttacaagg tcatccagac atgaaaggca cgccaggtgt ggaaatatct
    92821 actggttctt taggtcaagg tttttcagtt gcatgtggta tggctatggc atcaaagttg
    92881 gataatgctc cgtggaatgt gtatactttg cttggtgatg gtgaggttca agaaggaatt
    92941 gtttgggaag ctgctatgag tgctgcacat tataaacttg ataatttaat tgctttttta
    93001 gataataatg gacttcaaat agatggagat atagaaagcg taatgagttt aggttcaata
    93061 gttgataaat ttaaagcttt tggttggaat gtaattgaga tagatggaca tgattttgac
    93121 caaatatttg cggctcttga tatagctaaa tcaacagtta aaaaacctac aatgatagtt
    93181 gcaaaaacta taaaaggcaa aggaatatct tttatggaaa atcaagcagg atggcatggg
    93241 acagctccaa gtgatgagga gctagaaaaa gccttgcttg aattaggagg tgctgacaat
    93301 gagtaaaatg gcgacgagag aagcatatgg taaagcatta gtaaaattgg gtcaaataaa
    93361 tgacaatgtt gtagtattag atgcagattt atcaaagtct acaaaaacac atgattttta
    93421 caagtcattt ccagatagat tttttaatat gggtatagct gaacaaaatt taataggcgc
    93481 tgcttgtgga ttatcaactg ctggtaaaat accttttgca agcacttttg ctatgtttgc
    93541 tacgggaagg gcttttgaga ttataagaaa ttcagtttgt tatccaaagc taaatgtaaa
    93601 aatatgtgct actcatgcag gtcttactgt tggagaggat ggagcatctc atgaaagtgt
    93661 ggaagatatt gctataatga gagctatacc aaatatgaca gttcttgttc cagctgatgg
    93721 agttgaaaca gaaaaaatta tttttgaaat agctaagtat aatggacctg tttatgttag
    93781 attagggaga agttcagtac cagttttatt tgatgaagat tataaatttg aaataggaaa
    93841 aggtacagtc ttaagagaag gaaaggatgt atcaattata gcttgtggaa ttatggtaaa
    93901 tgaagctcta ttagcacaag aaaagttgca agaagaaggt ataagtgcta gagttataaa
    93961 catgtcctcg ataaaaccta tagacaaaga tttaatatta gaatcagcaa aagaaacgaa
    94021 tgctattgta actgtagaag aacatagcat aattggggga ttaggttctg ctgtaagtga
    94081 ggtagtagga gagtcttgtc caaccattgt aaagaaagtt ggaattaaag atacatttgg
    94141 agaatctggt actccaaatg aattgttaaa aaaatatgaa ttaacttgtg atgacataat
    94201 aaagactgtt aaagaagcta ttattgcaaa aagaatgtaa gagatataaa ttattcatgt
    94261 ttgttaataa tataatatat ttaaaagaga ggtataaagt gttatattaa tttatatctc
    94321 tctttttttt atatgatatc aatatatcaa aaatgtaata aaatattcaa atttttacaa
    94381 aaatagagaa aatattcaaa tatatattga ctattcagaa aaatatgact aatatataat
    94441 ttatagagaa actaatttta tatataatga ctacttagat aaaagaatct aaaaaaatta
    94501 tgagaggagg agtagggtat aaaatcagat tataagtttt aagttattat actaaaaagc
    94561 tataaaacag ttatcatgta ttttatgtta aaggaaattg taggtagttt atcgaattgt
    94621 ttaatcagaa gaaaaaattt cacatgggga ggtaactgag atatgtcaga aaaagtaaat
    94681 gttaaaacag tcatcagttt cgcaggtgcg tatgtagcaa cagtaatcgg ttctggattt
    94741 gcaacaggac aggaaataat gcaattcttc tctttttatg gttttgcagg tattattggt
    94801 gggataattt caatggtatt attctcatgg atgggtgctt cagttatgtc aaaaggtaaa
    94861 gagcttcaac ttaaagaacc tatcaaaatt tatcgtgttt attgtggtaa gtatttagga
    94921 atattctttg aatggtttgg acctttattc ttatttggtg ttttcgtagt aatgatttca
    94981 ggagcaggag caactttaac tgaatactat ggattaaatc catttgtagg tagagtaggt
    95041 atggcagtag tagcattatt aactgtttca ctaggtcttg ataaattatc aaagatacta
    95101 ggtggaatag ggcctataat aataatcttt acacttttag ttggtggtat aagtttagct
    95161 aaaaacatag gtaatatagg agaagctgca caagttctta gcactgtaaa gatagctaaa
    95221 ccagttccaa atgcctatct atctggtgta atatatacta cttataacac aattgttgtt
    95281 atggcattct taactggatt aggagcaagt gctgctaaca aaaaagaagc tatttgtggt
    95341 ggtatattag gtggagtagc acttatggct gcagctataa tgatgcactt agctattctt
    95401 tctgatatag gaaacttata ttcaaaagca ataccatcat tattcttagc agataagatt
    95461 tcaccagtaa ttggagtttt attctcaata attcttatat taggtatata tacaacagct
    95521 gtacctttat tatggtcagt aactaataga tttgtagatg acaaacatcc taagtttaaa
    95581 ttaataactt taatagcagc tatattaggt cttataggtg gcttcctacc atttgataag
    95641 ctggttggta ttttatatcc atatactgga tatatgggcg tcataatact ggtttgtgtt
    95701 ctttatagac agattacaaa aacatctgga tatcaagaag gaatcagtga caaataagta
    95761 ttttttaata ttgtaaactc aagagctata tgaaaacaat gaaaatgttt tcatatagct
    95821 ctttttattt tttagctcgt ttattatgaa atagaaaaaa catgtttttt agttacatta
    95881 catatattta taattatgta taaatatata ctaatcaata atttagagtc taagataagt
    95941 ttataaatca tatatttaga atatatggga ggagtgataa gattgaatgt aaagtttaat
    96001 attaaaggta taatttatgg agttatagct cttgtattcg ttataggggg atttatattc
    96061 ataccaagta tgtttgtaga gaaatctaaa cccatagatt atacagtatt acaaagaaat
    96121 tcaataccag aaaagatatt agatgtgatg gataagtata caaatgaaga aagagcatta
    96181 gcggctaaaa tcgataacaa aatatacatt atagtgacta gaggaaataa taaatatggt
    96241 atagaaatgg acaaaataga aagtgtggtt gaggaaggaa aggatgtttt gagagtcaag
    96301 ataaagtata aagataagga agattctttt ccatacatag ttgttgaaac aaatatgagt
    96361 gaacttccag atagaataga attaaatgcg acgaaataag aaggtatttt ataattaaat
    96421 aactgcatat tgtacaataa agtcatggtt tttattaatg taagtaaatt gtgtatggtt
    96481 cttattgttg taaaagccat gacttaaaat gcttataaag taagatatta acagtagtat
    96541 ttattactac attaaatggg gtctggaaat acttaatatt ctaactattt ggagtgataa
    96601 ttctagtttc agtaactatg tagtctaatt gtgcatcatg agtttctttt ggaatagaat
    96661 cgaatatctg gaagtcaaat gctatgccga tagttatagc atcttttctt aagttttcta
    96721 aaaatctatc ataaaatcct ccaccatatc ctaatctata gcaatgtata tcatatgcta
    96781 cagctggtac aattacaaca tctaaggcct taatatcaat tgtaggtgat ttttcgttag
    96841 gttctcttat tccatatgct ccaattctca atccctcttt taaatctgtt atttgagtag
    96901 ggattaatgt atgattttct tttattgtga tgggacttga tactattttc tttagagaca
    96961 aaagtttttt gattaaatta tctgtttgaa cttcattgtt aaaatttaga taaagcatta
    97021 tattagttgc atttcttata tcttccattt gaagtaattt ttcagttatt aaatttgaat
    97081 tactaagtac aaagtttgca ttcttatttt ttcttgattc aataactttt tttctaaatt
    97141 cttttttcat aaaataattc ctcccttaat atgttataat gtgtacagca attgtattta
    97201 atataaattt tagtataatt tattgtaata aagcaatata tttgggtaaa tgtaataaaa
    97261 ataacagcta gtcatataat aataatagtt tatgtaaaag gagatgtatc ttgtgatttc
    97321 aaagaagaaa gctatttttt taggggtgat tttagtaatt ataacagcta tggttacatc
    97381 agcatttcag ttgacattgg ggaataaagt tgtaatatcg aaagaactct atgaagacta
    97441 taaaaaatat gataagttgt taggactaga atctattata aaacaagatt tttataaaaa
    97501 agtatcagat actgatttgg taaatggagc agcaaaaggt ctatttctag gaacaaatga
    97561 taagtattct ggttattata ctaaagatga aatggagaat ctaattaatg atagtgaagg
    97621 ttcttatgtt ggtgtaggta tgtatatagg ggcatcaaaa gatggtggct tagtagtagt
    97681 tcccatgaaa gattctccag cagagaaagc cggtgtaaaa tcaggggata aattagtaaa
    97741 agtcaatgga aaatctgtct catataaaaa ttcagatgaa gctgttcgta tgatgaaggg
    97801 taaaaaaggt aaaacagttg aactgactat attaagagaa gataaacaat tgaactttaa
    97861 agtaaaaaca gaccagataa ttgagaagag tatagaaagt aaagtaattg ataatgattt
    97921 aggatatata gaaattaccc aatttatatc aagtacatat actgactttg ataaagcttt
    97981 aaaagaatta aaagcaaaaa atatcaaggg attagtaata gaccttagaa ataatcctgg
    98041 tggaatgcta gatatatgta aagaagttgc tgatgagtta attggtgaag gaactatagt
    98101 atatacaaaa gataataagg gaaatactga gtacttgaaa tctgataaag aaaaattggg
    98161 acttccaata gtagtgttaa ctaatggaga aagtgcttct gctgctgaaa tattaacagc
    98221 tgcaatcgtt gataataaag aaggtatttc tgtagggact acaacttttg gtaaagggtt
    98281 ggtacaatca gttgtaagat tgaaggatgg aacaggatac aagctaacta ctgctcaata
    98341 ttttacacct aatggggatt atatcaatga aaaaggtata aagcctacta ttgaagagaa
    98401 agatgaaaat aaacagttag atgtagcaac taagtggctt agagaacaga ttgataaata
    98461 ggatttaatt tttataaact tatactataa aataaagaac attataaaag agatgtctca
    98521 aaatgaactt tttagttcat gagggagtct ggaaatattt atgtgtattc tttaaataaa
    98581 aatttatttt ttaagtgata attaaatttt tacagacagg gctatggttt taaaaatcat
    98641 agccttattt tgatattttt taaaaacata ttgcaaccca gttgttccaa atattatatc
    98701 atttactttt aaaatatcgc aaactgcata ttatatattc attataatat aatttatcta
    98761 actagaacct cagt
//
LOCUS       DAEPHU010000004        82758 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 01A10CD0081
            SAMN05941466-rid12468953.denovo.004, whole genome shotgun sequence.
ACCESSION   DAEPHU010000004 DAEPHU010000000
VERSION     DAEPHU010000004.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941466
            Sequence Read Archive: SRR6291087
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 82758)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 82758)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068158.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 22:43:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,892
            CDSs (total)                      :: 3,805
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 87
            rRNAs                             :: 8, 1, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 55
            CDSs (without protein)            :: 55
            Pseudo Genes (ambiguous residues) :: 0 of 55
            Pseudo Genes (frameshifted)       :: 21 of 55
            Pseudo Genes (incomplete)         :: 28 of 55
            Pseudo Genes (internal stop)      :: 16 of 55
            Pseudo Genes (multiple problems)  :: 8 of 55
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..82758
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941466-rid12468953.denovo.004"
                     /strain="01A10CD0081"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            488..865
                     /locus_tag="KR231_000293"
     CDS             488..865
                     /locus_tag="KR231_000293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
                     /protein_id="HBH0002711.1"
                     /translation="MMIRKIPQAELKVMKFIWKVDVTVTSKDVIEAMEQKYGWKQTTT
                     LTLLSRLVKRGFLDAQKIDRYTHYTIRVKHKDYLSFETKDFLSNIHDDSLRSLISALH
                     DDENIGKDKLDFLESYFDNLKDE"
     gene            858..2006
                     /locus_tag="KR231_000294"
     CDS             858..2006
                     /locus_tag="KR231_000294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protease"
                     /protein_id="HBH0002712.1"
                     /translation="MNNYMLYVFENLIKTTIVCSLGICLLLFLKRYLFKKFSKRFNYY
                     IWLIIVFRMLLFLFNYTIVYEVKEPKENALGNNITQIDISTDNNLMLYVAYLWLFVTI
                     VIAVYTFIKYTRFKNLVVDVSYDIEDNDINCIYKNLLKELNIKKKIELRGSDELISPA
                     GMGLFKSYIFLPDYPYSKDELTWILKHELMHFKNKDILIKFLVLSVRIIYWFNPLVYV
                     MSNKVNLDCELCCDESVLVECSLKDKKEYALALIKSIKFSKNYNSKILTTEFDKTNLE
                     KRLESIVKKKGKSGILIAVLVFMTSITSFVEVDAQVRIDEGNNGMNNNINEFLLNKTT
                     DKIINIYYKDAPNEIRKFYEDKCELEGKIPRDYDIIEMDMKDYNQLIK"
     gene            2023..2625
                     /locus_tag="KR231_000295"
     CDS             2023..2625
                     /locus_tag="KR231_000295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454685.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan-binding protein"
                     /protein_id="HBH0002713.1"
                     /translation="MLTKLRKIVAIMCCLLLTFTSVAFADTSKEKGGSKETVPEKNLD
                     SFTLSGYIYTYENAPQEIRDEHKQNCEEINIDPKPDDEIFVPESANLMNEDNSKGVYA
                     SYTVSYNIGAKTITIMSNEYLTISTTKVIRKGNSGKEVKAAQIMLTLLGYNVGIDSSF
                     GSKTYNAVVSFQKKYGLSADGIIGPATWDKLGRLTDPTLS"
     gene            complement(2718..3740)
                     /locus_tag="KR231_000296"
     CDS             complement(2718..3740)
                     /locus_tag="KR231_000296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903176.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-hydroxy-acid oxidizing protein"
                     /protein_id="HBH0002714.1"
                     /translation="MDYNDLLKSARENFNGTCKVCKICNGLACAGDVPGMGGKGSGSS
                     FIENRKSLEKIKINMRVIHNVSKPDTSIELFGRKMSSPIFAAPVSGTILNMGGKVSEK
                     EYIEPVVRGCSNSGIYAMVGDTNVDTFLLDNLDVLKDNRGNGIVFIKPWNNSKIIDKI
                     RLSEEAGAFAVGVDLDACGLINNQFQENPFSPKTIDEIRELVESTRLPFIIKGIMTVD
                     DALMAVESGASAIIVSNHGGRVLDYTPGTCEVLPDIAKSVKGKITILVDGGVRTGVDV
                     VKMLGLGADAVLMGRPFVTASFGGGLDGVEFFIEKVRNELCETMILTGCQNVKDIDGR
                     VIWNLL"
     gene            complement(4069..4251)
                     /locus_tag="KR231_000297"
     CDS             complement(4069..4251)
                     /locus_tag="KR231_000297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0002715.1"
                     /translation="MYKDKSDECIHLMTAYIDSISGYYSFIDTQLEDFMMKYGENIVD
                     SNLHSIMMLLCKWGLS"
     gene            4564..4983
                     /locus_tag="KR231_000298"
     CDS             4564..4983
                     /locus_tag="KR231_000298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3785 domain-containing protein"
                     /protein_id="HBH0002716.1"
                     /translation="MSLYKFIYDDKEYLLKEENCSALINDEENPVQGVSISKIIDILN
                     EAEEVDFDVEYYQEACPLCLEGVKEKKKFFPFLEYHFYIFSKDGEYVISNISVDYKGL
                     SFNKLSRANKVDNSYIVSVIICENCQDYIVQIENCIV"
     gene            5114..6955
                     /locus_tag="KR231_000299"
     CDS             5114..6955
                     /locus_tag="KR231_000299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GGDEF domain-containing protein"
                     /protein_id="HBH0002717.1"
                     /translation="MEEIDDTILDSMFKLTLNERLLTNNDFIENKIDVVKNLIDCYKT
                     EQNSLMLLKSNFLLALLYGIQGFSEKMKEYILISCKYIDKCLPKDYKFLARFYSQIAI
                     LSLKNEDVNKANLYMDKFNLICDENNFLIEEIIFKSQLIYIKASKCIESSVIIKEIET
                     LYIKIKEINDFNCKKIYFFIIGKIYFLFLDDALIAKVNFLKARKYADLLKDMQVSSLC
                     NIKIGECECSFENYECSMEYFNEVISNKKYRNVNIIQKYRASNNITKILIKTRNYPVA
                     INNLAKSEVYLEKIKNHSLKEVEKFDLFISLAMYYAKSNEKSFEQSICYLDRAKNILN
                     MIKNIEEYIIYDLEIIYHQAKIYYIFGYYDNALNTNKKLLEKSKNAKNYNYVKLAYKS
                     IYLCFEKIQNYEMSMKYFKMYYELKMMYIKARNRNYIDSLNYRHEYIEKEINNMRKVK
                     LDLDKKKYVDHLTSAYNRTFLNDFLEKQEVSEYCTAFMIDVDYFKEYNDTYGHYNGDI
                     ALKNITIIIKKYLKKDMLMIRYGGEEFLILSVCKDYKKSKIFGRKLCRIVKKFLNNNL
                     TVSIGIDTCKNSSIDIKEIIENADKALYKAKESGRNRCLHYHDFKNF"
     gene            6982..8868
                     /locus_tag="KR231_000300"
     CDS             6982..8868
                     /locus_tag="KR231_000300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GGDEF domain-containing protein"
                     /protein_id="HBH0002718.1"
                     /translation="MKRSLIEDLKRNINKIEYDMLTKFYLNLTDLNYILDYHKDLLNT
                     KLEDNSRVYTLYLISLINYIKKDREASYNYLIESLKYIKKLSLKDDSDIISKIYIYLT
                     LSAISIRKYDKVNNFYFSAKKIIRQNHLNELLVLLNMSLCVEISALYQTKTDVIALVE
                     EVSFFKTLKNKALVSRANYIFGRVYLYLFNNFIKSMEYLIECLKLAQENNLYSIEAFC
                     KCIISLCYLESGNNVEAIKYINNVLDVAHSNNSISVTERVSIKIDLIWAYLKEDMNKE
                     AEVILLKTIKLMKVVEGVYKDYLYSFIFLYSAEIELKKDNCSFEKVNTYLILSKNIYK
                     SFGDVFIYNSKLDYIYKLYGDLYIKFGNIDEGISCYIKGLNLVKKSSLNLRKISIFYG
                     LIANGYELKKDFKLAIEYYKSMDWYSDRWEKNNSYKTSQAIHKQYELRQKQESLRLLV
                     DDNKKLENDILKDGLTKLYNRRYLEQQLDLFNETRDKNMVAILVDIDCFKSYNDNYGH
                     LAGDKVIVKVTDIIRSVFIDITEHIIRYGGEEILILVDSIESIGVEEIDNIELYIKRV
                     FKLLEFEGIEHIYSKIKNYITISAGVSIKRCRSRKDVEILIEDADKNLYKSKKAGRNQ
                     YIII"
     gene            8876..10876
                     /locus_tag="KR231_000301"
     CDS             8876..10876
                     /locus_tag="KR231_000301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HBH0002719.1"
                     /translation="MILLRKKIGIIASDIELKERIEELYREDVENGTIIIDILNLDLM
                     ENQGRILVEKGAQAIIGRGGGYSLVIDTVNVPVIPMNMKSTDLLRAIEIAKKYSKKVV
                     LILGDNEVSFDYVGWRNVISTEITEEWFESKYEIRSKVVKYIDQKDEIVIVGGGLACS
                     FARQYGIDSVFATASDESIREAVEYCKKLLDTLGEEKFNNEVLRNILDGIKDGVIAID
                     SNGSIILYNESAKNMLKVERKCALNKYILDVFPKMEWMLDCLHEKEDVEDRKIRNINN
                     LIVNTRTTLIKVDNSTYGVLGIIQDITKLQNLERKIRFDLNQKGLYARYTFDDFLFKD
                     KLTKEFIEEAKKIGKSDYTTLLYGESGSGKEIIAHSIHNISKRKDRPFVAINCATIAE
                     NLLESELFGYEEGAFTGARKGGKRGLFELAHGGTLFLDEINSLSFNIQTKLLRVIEER
                     QIMRIGSDYIIPLDIRIIAATNESLTEKIVMGTFRADLFYRLSSLEINIPPLRDRRED
                     IIPLFNNFVNEVLKDDGLNGINSIDENFVLTKDEMDKLYNYSWPGNVRELKTIAQKYV
                     VTGKIKLRQDRDFKTKKLLPNSEVDKFNSETTASVEVQDESINISKINDGKISIDIKE
                     VNKYVEEKIISMLFAQGLSKNEVAQVLGISRTSLWKKYNKNI"
     gene            11138..12397
                     /locus_tag="KR231_000302"
     CDS             11138..12397
                     /locus_tag="KR231_000302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class I/II-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="HBH0002720.1"
                     /translation="MSQSMVGKHAMWPKENDVIFSISGRAQAAEKAFGMDNVINATIG
                     ALMDDSGKLITMKTVYEEYKALDNCEIGAYAALEGQPDYLEAVKKVFFRDYLPEGHIR
                     VLASPGGSGAIKLAVWNYTNEGDEVLTSDWFWSPYVSIAEEANRKVVNYQLFDENRRF
                     NFESFKEKFVNIAEKQGRVFTIINTPAHNPTGYSVADDEWDKILDLSKEVAKDKDKKI
                     IFFVDSAYIDFAGDDDVCRKFFKKFSNLPENVLVLVGFSMSKGFTAYGMRMGAIICIS
                     SSEDVAEEFHYSCVHSCRANWSNCNRSAMAVLSNIVNDPKKFKEYEDEKEIYKNMLTR
                     RADVFVKEAERVGLEILPYIAGFFVSIPCDNPKEVCEELTKHNLFAVPLKMGLRFAVC
                     AVSEDKCKKAPSIIKEALESLEVKINN"
     gene            12458..14245
                     /gene="iorA"
                     /locus_tag="KR231_000303"
     CDS             12458..14245
                     /gene="iorA"
                     /locus_tag="KR231_000303"
                     /EC_number="1.2.7.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="indolepyruvate ferredoxin oxidoreductase subunit
                     alpha"
                     /protein_id="HBH0002721.1"
                     /translation="MKQLMTGNEAIARGAYEAGVKYASAYPGTPSTEILENIATYKDA
                     IVAEWAPNEKVALEAAIGGSIAGARTMASMKHVGLNVAADPIFTYAYTGVNGGMVLIT
                     ADEPGMHSSQNEQDNRMYAKFAKIPLFEPSTSQEAKDMIKEAFEVSEKYDTPVLYRVT
                     TRLCHSKGLVECYDREEVEIKEYVKNAKKMVTVPANAQIRRGVVEERMEILKKFSNET
                     DLNYYEINDTKIGVIASGMCCNFAKEVFGKNASYMKLGFTNPLPYEKIKEFAEKVDKI
                     YVIEENDPFIEEQIKAYGIDCIGKDVIPPYGEMTPDVLRKAIFGKTNDTIEYKSELVT
                     PRPPSFCAGCPHRGFFYELGKRKNLIVGGDIGCYTLGFAPPYNGIDYVVCMGSAFGTA
                     HGAQKVLNMKDDNEKRLVGVLGDSTFFHTGINGLLDVVYNRGNSISVILDNRITGMTG
                     HQENPGSGYTLQGAKTKEVDIEGLVKACGIEHVRVINPNNLKEVNEALDWALAIEDEP
                     SVIITRWPCVLKKFSKEDIEEFNNPFKTKCKVDHDKCIGCKLCLKTGCPALSFDKENK
                     LSNIDRNQCVGCGVCAQVCPKQAIVKEEK"
     gene            14247..14822
                     /locus_tag="KR231_000304"
     CDS             14247..14822
                     /locus_tag="KR231_000304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="indolepyruvate oxidoreductase subunit beta"
                     /protein_id="HBH0002722.1"
                     /translation="MTKSILLVGVGGQGTILASKLLTMGLMEAGYDVKMSEIHGMSQR
                     GGSVSSQVRYGDCVHSPVIEIGGADILVSFEKMEALRWFNYLKPEGKALVNNHRIDSM
                     TVLIGGAEYQESDIDAELSRLNAKVINAADKAEELGNSKIMNVILLGCLVKSMQLESI
                     DWEKIISENVKPKFVELNIKAFHEGMEMVSK"
     gene            14875..15945
                     /gene="buk"
                     /locus_tag="KR231_000305"
     CDS             14875..15945
                     /gene="buk"
                     /locus_tag="KR231_000305"
                     /EC_number="2.7.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="butyrate kinase"
                     /protein_id="HBH0002723.1"
                     /translation="MTYRILAINPGSTSTKIAVYDGEEQILVKTIDHPAEEIAKYNTI
                     QDQFEMRKEAVLNILKENSIDLKSLSAIVGRGGVLPPVKSGAYLVNEEMIDVLRHRPV
                     LEHASNLGAVVAHAISEPLGINSYIYDSVAVDELIDVARISGLCGMDRSSAGHALNTR
                     AMALKYAKDKGKDYKSLNLIVAHIGGGVSIYLHEKGRMVDMLSDDEGPFSPERSGRVP
                     ATKLVAACYSGQYSEREMTKKIRGKGGIVSYLNTVDAREVEKMIAEGNEEAKIIYEAM
                     AYQLAKGIGELATVVDGKVDAIIITGGIAYSEMFTSMVKKKVEFIAPVEIMAGENELE
                     SLAFGTLRVLNGEEEARIYSEN"
     gene            16163..16864
                     /locus_tag="KR231_000306"
     CDS             16163..16864
                     /locus_tag="KR231_000306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0002724.1"
                     /translation="MGKISLKSMIRLFSGFFIFAISSVLMINAHVGLMPWDVLHQGLS
                     IKLGITIGQASIMVGVVIVILDAVFGENIGWGTLLNMTFIGIFIDLVIFSGVIPHASN
                     TYIGVFMVVIGIILAAIASFLYLGVCLGSGPRDGLMIALQKKTNKSVRLVRTILEILA
                     LVVGWLLGGSVGIGTLVSALGLGYVLQIVFRIFKFDTKLLKHRFIIDDIREWKEKKSN
                     EHKCKSSIVIKNEQN"
     gene            16924..17430
                     /locus_tag="KR231_000307"
     CDS             16924..17430
                     /locus_tag="KR231_000307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX domain-containing protein"
                     /protein_id="HBH0002725.1"
                     /translation="MELWDLYNADGIKTGNVIKRGNSIEEGYYHLAVEVWILNSNSQI
                     LIQKRSKSKKTLPNMWGMTTGCIVSGEDSLEGAIREAKEEIGIDITKDEMKVFRSMIH
                     EDTLWDVYLVKKEYDISKAILQEEEVSDIKWVSTDEIRQLLKEGLFFEYPEIYELLYE
                     IDNNKLNI"
     gene            17605..18627
                     /locus_tag="KR231_000308"
     CDS             17605..18627
                     /locus_tag="KR231_000308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HBH0002726.1"
                     /translation="MEDNKGLARDSSKYKIVSISVVVIILITFWYMLNMVLLTFIMTF
                     IFYNLLVATRKRIKKFSSLNIPDSLIIIVLYALFAILLVLISYAVVPIIIVQLTELSR
                     VFSDFDVNQFAQSLGPKLYPIVSKLDFNKYISQAGLLIASTATKVGSFGVNILLAFLL
                     SLLLLLEKNEIKNFGDKLSDSKISFIYNSLVFFGKSFVKNFGEVMKVQVMIAFINSVV
                     SMIFLGFMGFPQIWALGFMIFVLGLIPVAGVIVSLIPLTVIAFNTGGITKVFGVLLMI
                     CIVHAVETYILNPKLMSNRTKLPVCFVFIILLVGEHYLGVWGLLIGVPIFMFLMDILG
                     VKFTSR"
     gene            complement(18774..19082)
                     /locus_tag="KR231_000309"
     CDS             complement(18774..19082)
                     /locus_tag="KR231_000309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1540 domain-containing protein"
                     /protein_id="HBH0002727.1"
                     /translation="MKNNNLNCAATNCAYNTSGYCYAGSIKVDGMQATTTENTYCASF
                     EDKYTSGITSRSNETNQVDTDNIHCEAVKCKYNKNELCKAEKVHINERNASCETFEMK
                     "
     gene            complement(19142..19570)
                     /locus_tag="KR231_000310"
     CDS             complement(19142..19570)
                     /locus_tag="KR231_000310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0002728.1"
                     /translation="MNNKLHELEKNLPEISCSFCTHLSFKGPSLDYRYDIRCVISDTK
                     PDFRGCCEYFEPEYTELNTGDLDNLYINFLETCLKVNYNDYINSMYWKLFKERTLLEN
                     NFKCSICGSTENVDVYHVNKNLGRETSKDVVVKCDKCNCK"
     gene            complement(19793..21250)
                     /locus_tag="KR231_000311"
     CDS             complement(19793..21250)
                     /locus_tag="KR231_000311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbon starvation protein A"
                     /protein_id="HBH0002729.1"
                     /translation="MTTFLIGLAILLIGGALYGAYCEKVFGPDDRKTPALAQSDGVDY
                     VPMKKWKNSLIELLNIAGTGPILGPIQGILFGPIAFILIPIGCVFGGALHDYMSGMIS
                     IREKGAQMPSLISRFLGNKVFQVYNIFLCLLMLLVGAVFIYTPGDLVVTQILNMKSTI
                     NNPVVWIVYGLIFLYYLCATLFPIDKIIGKVYPIFGAILLLSAAGVGIGIFTQGYDLA
                     NLSLANWKGIHPDGIPLIPTFFVTVACGIVSGFHSTQATLIARSVSNEKEGKTTFYNM
                     MILEGLIAMIWAAAAMGIYNKGIPKELVGSPDVIGLVARDLLGSIGGIIAIIGVIVLP
                     ITSGDTALRSLRLMLADYFHYDQKEKKHRVILSICIFIPVIAILIFAKLSASGFNILW
                     RYFSWSNQTIAIFAFAMITVYLIIKEKNYIISLIPGMFYSFVIFSYIFNAQIGFNLNI
                     NISYVLAAIFTVLYAILTVRSGRKLKSKADTKLAD"
     gene            21668..22582
                     /gene="nadA"
                     /locus_tag="KR231_000312"
     CDS             21668..22582
                     /gene="nadA"
                     /locus_tag="KR231_000312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quinolinate synthase NadA"
                     /protein_id="HBH0002730.1"
                     /translation="MDKDLTYQIKELKKEKNAIILAHFYQPPEIQELADAVGDSYYLS
                     EIARDCKEEVVVFCGVRFMGESAKILSPEKTVLMPVSNAGCAMADMVDEEGVIKLKQQ
                     YPNALVVCYINSTAKVKAHCDVSVTSSSAIKILENIDNKEIIFLPDKNLGGYIAEQFP
                     DKNFIFWDGYCKYHNNIRAEEIIELKDKYKNAEVLVHPECKKEIRDLGDYVGSTSGII
                     KYATNSKNKDFIIATEEGILHELKKNNPNKNFYIPGGKILCTDMKKTTLENLYSTLKN
                     MENEVIVEDEIMEKALNSLLNMHKLAEG"
     gene            22595..23896
                     /locus_tag="KR231_000313"
     CDS             22595..23896
                     /locus_tag="KR231_000313"
                     /EC_number="1.4.3.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-aspartate oxidase"
                     /protein_id="HBH0002731.1"
                     /translation="MNLEQDVLIVGSGVSGLYCALNLDKSLNVLVVSKSTIENNNTYL
                     AQGGISTARNIDDIESFVEDTMKAGQYKNRVEAVQVLADESIENVGQIVEYGMPLDKE
                     NGEIDYTREGAHSVNRIVHSKDNTGEVVFKTLLKEAKTRENITLIEDAYLLDILKDGN
                     KCIGARIFKSKKEIHVFSKIVVLATGGIGGLFKNSTNQRHLTGDGIAIALRNNIKIEN
                     LEYIQIHPTAFYEENNEGRRMLISESLRGEGAKLLNKNKERFVDELLPRDVVSKAIFE
                     QMEKDKLPYVYLDATHLDSEYLINRFSFIYNECLARGTDITKECIKVSPAQHYFMGGI
                     HVDLDSKTSMENLYAVGEISCTGVHGANRLASNSLLEGLVFSKRAAKNINSVIDNVKV
                     KFIDVPDMDIDIEQVKKENKILVIKEIERTSEDFGDELFDY"
     gene            23877..24713
                     /gene="nadC"
                     /locus_tag="KR231_000314"
     CDS             23877..24713
                     /gene="nadC"
                     /locus_tag="KR231_000314"
                     /EC_number="2.4.2.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxylating nicotinate-nucleotide
                     diphosphorylase"
                     /protein_id="HBH0002732.1"
                     /translation="MNYLIIDRMIQDALIEDVPSEDITTNSIVDENSKSTVDLICKQD
                     GIIAGLGVFKRVFEILGDVDVKLYKNDGDRVKNREKIAVLTGSTRNLLVGERVALNYL
                     QRMSGIATITSRYVEKLEGTNTKLLDSRKTIPNLRILDKYSVKVGGGCNHRFNLSDGI
                     LLKDNHIGAAGSVKKAVELARKNTSFVRKIEVEVETLDMVKEAIEANADIIMLDNMSL
                     EMAKQAVDIINGRAIVEFSGNVNLDTIEDIGKIGVDVVSVGALTHSVKALDISMKNLR
                     NI"
     gene            24969..25301
                     /locus_tag="KR231_000315"
     CDS             24969..25301
                     /locus_tag="KR231_000315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DsrE family protein"
                     /protein_id="HBH0002733.1"
                     /translation="MKVAYIFSSTNTHKILDKMIIPQLEQGTHGVDVLGMFFFMDNTL
                     FLSKGNPVGERLSKLHEKTDMIIMACDQCAIERGIENNLVDGATIGCFPNLYACLGSA
                     GVDQVITL"
     gene            25463..25648
                     /locus_tag="KR231_000316"
     CDS             25463..25648
                     /locus_tag="KR231_000316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0002734.1"
                     /translation="MSEKYADKLEIKLYQAGKDFSYIKKYGIITKGTLIINQKKKYDR
                     LNKDTIERAIVEAINNN"
     gene            25675..26760
                     /locus_tag="KR231_000317"
     CDS             25675..26760
                     /locus_tag="KR231_000317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="permease"
                     /protein_id="HBH0002735.1"
                     /translation="MNILEIVLNGVKDTIVASIVTLNGASGWLMISFILAGVLHNVLT
                     PRRFQKQLGNKKFSSLIKSTISGMFLPICSCGVIPLGISMYYSGAYLGPVLAFMTSTP
                     IINPIAVVLCLGLLGPKVTIIYLIAGFLVPFLVGFLGNCFGKEELSLHNDSEEEVIEL
                     EEEKRSFMENMIDGLKWSFGELALTISKYVVMGMVFAGFITTIFPNSIIQKYLGNPGL
                     LSLGSIAILACVMYVCAVGHIPFIAALVASGASPGIAITFLIAGAATNLPELISMFKL
                     IGKRTVIIYSVTLTLSSIIIGYITNLLLVNNNSVNLDATNSSIQLANKLMLNIPDSFE
                     YVCTILIILFAFKSIIPKMKEVIGNHA"
     gene            26753..27211
                     /locus_tag="KR231_000318"
     CDS             26753..27211
                     /locus_tag="KR231_000318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0002736.1"
                     /translation="MLKKIVIISCIVVVLIILSKIVDDNIKEDASIPNVNKETLEYFR
                     KNYKEDIITCAEEDLNNDGKKDLVVIYKKSNNSNEMVVVVSDKNSHYITKPIPAPIEN
                     QTITFKNIDDKAPIEVIVSGSKNGNVGYAIYRVEGKKFVDLFGEDMDKCC"
     gene            27246..28337
                     /locus_tag="KR231_000319"
     CDS             27246..28337
                     /locus_tag="KR231_000319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HBH0002737.1"
                     /translation="MKLSKKIQALILFGVMGTSILTGCSSKPKEKEEAKTGKDDYTIT
                     VGYYNCDHMTAGPVAESAGIYKDLGLNVKTVGNGKVPEAMAAGKMDAGYIGTKGLVGA
                     IPKGSPITIAANNHTGGSEYLIVSKDIKEPKDLIGKKIATDMSDFLWTSDYGPETGLP
                     TDPSKYEVVNMDSDKDKYLALKTGKIQAFTSCDPWGSVAENDGAGKIIASTQYKEKAN
                     GKEYNCCSFSLNKNFIKEHPDLAKKLVLAHTKAIEYIYTNPAEAAKIFAKYYNVEEEV
                     ALRTIYKKTVGEGRTLTWKVTGEEYKNNLQMYKDLKALDDIPKYEDTIDTSLLDSCGA
                     DDFDKFIKEKVNPEFPEGMSYEDWKAKVL"
     gene            28342..28566
                     /locus_tag="KR231_000320"
     CDS             28342..28566
                     /locus_tag="KR231_000320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0002738.1"
                     /translation="MENMKNIIILFIIILGSIFIIFFNFEDKEEIKGKLRIGVSDDTS
                     GFVINYMVNRDYFENIKVSDIMDIFTINDC"
     gene            28576..29139
                     /locus_tag="KR231_000321"
     CDS             28576..29139
                     /locus_tag="KR231_000321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0002739.1"
                     /translation="MQWALSSEEIDIAIICKDAAKQYVNVNSGFEIVGTVVQNSDIFL
                     LSDNNPEKIGVIQNRDYQSELVKKYYKNVEVAPLLGTALAYGLESNLVDGVVIDCIKS
                     IGLEGKRKSTTKLGDYDTYVLVVSKEFKKSKAYSDFITLYNKSVDALKNKATFKKALK
                     EYRNIRNIDMEEISNWKLKFLKIKAID"
     gene            29100..29729
                     /locus_tag="KR231_000322"
     CDS             29100..29729
                     /locus_tag="KR231_000322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBH0002740.1"
                     /translation="MEIKISKDKSDRLTKKKTDGSMDILYKIILLVIIFLVWHFAAKD
                     IGSSLLLPMPVDVIKGFFFCVTDAETVTNLFITLQRVLKGFMYALLFGLPIGFIMGFS
                     KTFERVLSPVVDSVRQVPIMAWVPLTIVWFGIGDGPTIFLIAFSGVFPIILNTIQGVR
                     AISKDYYNAARSMGASPIVIFTNVIVPASLPDILTGSRIAISTGWMSVI"
     gene            29769..29906
                     /locus_tag="KR231_000323"
     CDS             29769..29906
                     /locus_tag="KR231_000323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitrate ABC transporter substrate-binding
                     protein"
                     /protein_id="HBH0002741.1"
                     /translation="MVQAQTLMHTDVLIGLMIFAALIGFIIDRVLKFINKILCRWRFA
                     D"
     gene            29906..30658
                     /locus_tag="KR231_000324"
     CDS             29906..30658
                     /locus_tag="KR231_000324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH0002742.1"
                     /translation="MKLSVRDINKTFVNNRVHTKVLEDISMDIDDGQFVCLLGPSGCG
                     KTTLLTIIGGFQKSERGDVFINDKRVKKPGIDRAFIFQNYALFPWKTIRGNVLFPMKQ
                     QKIPKEKREEMLEELLVMSDLKGKEKLFPHQLSGGMKQRVAMIRALACNPEVLLMDEP
                     LGAVDFQMRQNLQEELERIWIKKKITALMVTHDVDEAVYMSDRVIVMSRDKGRIIDDI
                     NIDIPRPRIRGSQKYEEYKNKLTDTLSKCYEV"
     gene            30671..31156
                     /locus_tag="KR231_000325"
     CDS             30671..31156
                     /locus_tag="KR231_000325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0002743.1"
                     /translation="MSQIEKYNSLDNTQQKIRISIMDMIIDKGSSVTLQEVTEYISKK
                     LNIEKEYIERTLQYFIYKNIMVVDGNSINFIYPVSALPTNHKVTLRDNRSFSAMCAID
                     AIGTSCTFNQDIKINSICSATGKEIEVIIKNEKIEYVNNPNLRVLHINLDKHLNWAAS
                     C"
     gene            31163..31312
                     /locus_tag="KR231_000326"
     CDS             31163..31312
                     /locus_tag="KR231_000326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0002744.1"
                     /translation="MNFFWTKSDFDAWTNEAGLSNDEDIYCLDINEAIVESYKIFKLK
                     QKVLS"
     gene            complement(31449..32270)
                     /gene="yidA"
                     /locus_tag="KR231_000327"
     CDS             complement(31449..32270)
                     /gene="yidA"
                     /locus_tag="KR231_000327"
                     /EC_number="3.1.3.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-phosphatase"
                     /protein_id="HBH0002745.1"
                     /translation="MYKLIALDIDGTILNTQKRITPEVFESIQEAKRAGAKVVITTGR
                     PLPGVKELLNQLNLTDEGDYVICFNGAIIQEVKSEKIIHDVEMSLDDFDFIYNNVCKK
                     YKTKIHINTMTNLITPNETPGKYTLHEAKLNNIEVKYIQKDKIDESIKICKIMIVDEP
                     ERLEEIIQQLPKNLFNKYTIVRSAPFYLEFLGKTTNKGTALKTLCTNLNIPIENAIAV
                     GDEENDQHMIKYAGLGVAMGNARNSIKEIADYVTDTNNENGVAKVINKYILNKAI"
     gene            32763..34457
                     /locus_tag="KR231_000328"
     CDS             32763..34457
                     /locus_tag="KR231_000328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M3 family oligoendopeptidase"
                     /protein_id="HBH0002746.1"
                     /translation="MKFSEFKYERPNYNSMKKEFLSCVEDINNSRNYKEQQKNIHKIN
                     LLRNKIETLSNIASIRYSTDTFNKFYKEEKNYWDEYMPLYEELNSYFYNAIVNSKFKY
                     DLIKEFGEQFFTIVEYSLKSFSKEIISELQEENKLCSEYTRLLASAEIMFDGKIRNLS
                     GMGKFMYSKNRKTRELANKAYYNFFEENETKFDDIFDKLVKLRDKMSKKLGFEDFVEL
                     GYVRMMRSDYREYMIKNVRKQVLKYVVPMANELYEKQAKRIGLEYLSYIDEGVEFLTG
                     NASLKGDSRYIIKNGKRMYSELSKETNEFFDFMLENELMDLETKKGKGAGGYCTYIPD
                     YKSPFIFSNFNQTADDIDVLTHEAGHAFQLYMSRWIDMPEINFPTLDSCEIHSMSMEF
                     ITWPWMDLFFKEDTDKYKFTHLSSSIKFIPYGVIVDEFQHYIYKNPNVDKSKRKEIWR
                     FLEKKYLPHRKYGDNSFLERGCWWFKQGHIFKNPFYYIDYVLAQICALQFWKKMIQDR
                     DAGWKDYINICKVGGTKSFLDIVSMGNLYSPFDDGCIESIIGDVKSWFDEINDSKL"
     regulatory      34789..34899
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00504"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="glycine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="glycine"
                     /db_xref="RFAM:RF00504"
     gene            35003..35374
                     /locus_tag="KR231_000329"
     CDS             35003..35374
                     /locus_tag="KR231_000329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GrdX family protein"
                     /protein_id="HBH0002747.1"
                     /translation="MIIITNNPKVKEEVQGREVLFKDTTYIGILEASRDLIHEGYELL
                     SHPLYGSVKPNETPYRTVILKKGNRLDINSLTLIEEAIITASKFQNNKKTPKWTESVQ
                     DDFRVIDYDIFYNTIQRMQYE"
     gene            35471..36418
                     /gene="trxB"
                     /locus_tag="KR231_000330"
     CDS             35471..36418
                     /gene="trxB"
                     /locus_tag="KR231_000330"
                     /EC_number="1.8.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin-disulfide reductase"
                     /protein_id="HBH0002748.1"
                     /translation="MENVYDLVIIGSGPAGLAAGLYGARAKLKTLILEKDKTGGQIVI
                     THEIANYPGSVPNATGPSLIARMVEQCKEFGAEMLRDNIVDTELDGDIKVLKGEKAEY
                     RAKAVIIGTGATPRKIGCPGEKELTGKGVSYCATCDADFFEDFEVFVVGGGDSALEEA
                     MYLTKFARKVTIVHRRQGFRCAKSVEEKAKANPKIEFLLDTVIEEIKGDGILESVVFK
                     NKVTGETHEYFADEEDGTMGVFVFVGLDAQTDLFKGKVDMDEKGYIITDEDMRTNIPG
                     VFAAGDCRSKTLRQVVTATNDGAIASIVAEKYIDEKFGN"
     gene            36522..36839
                     /locus_tag="KR231_000331"
     CDS             36522..36839
                     /locus_tag="KR231_000331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol reductase thioredoxin"
                     /protein_id="HBH0002749.1"
                     /translation="MLDLDKATFEEEVLNAEGFVFVDFWSEGCEPCKALMPDVHKLAE
                     TYGDKIKFCKMDTTKARRLAIKQKVLGLPTMAIYKDGEKVDEVTKDDATVPNIENMIK
                     KYL"
     gene            37108..38394
                     /locus_tag="KR231_000332"
     CDS             37108..38394
                     /locus_tag="KR231_000332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006439082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine/sarcosine/betaine reductase component B
                     subunit"
                     /protein_id="HBH0002750.1"
                     /translation="MRLELGKIFIKDIQFGDVTEVKDGVLFINKQEMLQEIGGDEHIK
                     SIDIELARPGESVRITPVKDVIEPRVKVEGNGGIFPGIMSKVDTVGEGKTHALKGVAV
                     VTTGKIVGFQEGIIDMTGEGAKYTPFSKLNNVVVIAEPIDGLKQYAHEKAVRMIGFKA
                     AMYLGEVARNLTPDEVSVYETKPLLESIKEYPELPKVGYVYMLQTQGLLHDTYVYGVD
                     AKQIVPTLLYPTELMDGAIVSGNCVSACDKNPSYVHINNGVVEDLYARHGKDINFVGV
                     IITNENVYLADKERSSNWTSKLCKYLGLDAVIVSQEGFGNPDTDLIMNCKKIEMQGVK
                     TVIVTDEYAGRDGGSQSLADADVRADAVVTGGNANQVVVLPKLDKVIGHLEVVDVIAG
                     GSDGSLRADGTIEVEIQAITGATNETGFGHLTAKGY"
     gene            38506..38979
                     /locus_tag="KR231_000333"
     CDS             38506..38979
                     /locus_tag="KR231_000333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011986236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_except=(pos:38638..38640,aa:Sec)
                     /transl_table=11
                     /product="glycine/sarcosine/betaine reductase complex
                     selenoprotein A"
                     /protein_id="HBH0002751.1"
                     /translation="MSLLSNKKVLIIGDRDGIPGPAIEECVKTVEGAEVVFSSTECFV
                     UTAAGAMDLENQNRVKDAADKFGAENVVILLGAAEAEAAGLAAETVTAGDPTFAGPLA
                     GVALGLSVYHVVEEPIKSLFDESVYEDQISMMEMVLEVEEIEEEMSGIREEFCKF"
     gene            39011..40321
                     /gene="grdB"
                     /locus_tag="KR231_000334"
     CDS             39011..40321
                     /gene="grdB"
                     /locus_tag="KR231_000334"
                     /EC_number="1.21.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_except=(pos:40058..40060,aa:Sec)
                     /transl_table=11
                     /product="glycine reductase complex selenoprotein B"
                     /protein_id="HBH0002752.1"
                     /translation="MGKLKAVHYINQFFAGIGGEEKADTKPHVAETLPPISLQLDKLL
                     GEDIEIVGTVVCGDSYFNENIDSASEEVLSMVKGFEPQLFIAGPAFNAGRYGVAAGTI
                     TKVVKDALNIPALTGMYVENPGADMFKKDVYVVETSDSAAGMRKALPKIAKLAVKLAN
                     GEEIGTPKDEGYIARGIRVNYFHEDRGSKRAVDMLVKKIKGEPFETEYPMPNFDRVDP
                     SKAVKDLSKCKIALVTSGGIVPKGNPDRIESSSASKYGTYSIAGVMDLTEETYETAHG
                     GYDPVYANLDADRVLPVDVLRDLEKEGVIGKLHETFYTTVGNGTSVANSKKYASEIGA
                     ALVADGVDAVILTSTUGTCTRCGATMVKEIEKTGLPVVHMCTVVPISLTVGANRIVPT
                     IAIPHPLGNPALDPTEEKALRRGLVEKALNALTTEVDGQTVFEK"
     gene            40577..42109
                     /locus_tag="KR231_000335"
     CDS             40577..42109
                     /locus_tag="KR231_000335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014520415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketoacyl-ACP synthase III family protein"
                     /protein_id="HBH0002753.1"
                     /translation="MTYPVLKGAGYVLIHTPDMIVQNGSTCTVERATNPDSEFLKEVS
                     NHIRSYEDVVNYMPNQVYIGNRRPEELRDLPMPWCEQKIEGTRNGKFGEIMPQDEFIA
                     LMQISDAFDLVKLSQEFIDEVKPKIENNYPEIAPFVGKLKGDDIEEGKELVATHIAEG
                     LYHDGKFVGYVKRAHDVDVNLNAHTMFENLVVKASGVLSAIQMLRHSKIDPAEIDYVI
                     ECSEEACGDINQRGGGNFAKSIAEIAGLQNATGSDTRGFCAAPTHALIQAAALVKAGI
                     HKNVMVVAGGASAKLGMNAKDHVKKGLPVLEDVVGGFAVLVSENDGVNPVIRTDLTGK
                     HTVGTGSSPQAVMTALITSGLDRANLKITDVDVYSVEMQNPDITKPAGAGDVPEANYK
                     MIGALAVKRGDLEKKELKDFVSNKGLPGWAPTQGHIPSGAPYIGFLIDDLTTGNRNRA
                     MIVGKGSLFLGRMTNLFDGVSFIAERNTGVTEETSGISKDEIKKIIAESMKKLALDML
                     EE"
     gene            42120..43265
                     /locus_tag="KR231_000336"
     CDS             42120..43265
                     /locus_tag="KR231_000336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine reductase"
                     /protein_id="HBH0002754.1"
                     /translation="MSKKVIADVFLEVANAIESGEFGKKVKIGVTTLGSEHGVENMVN
                     GAQLAKSNLFDIVLIGPKVETDLEVVEVNDEKEMHAKMEELLDSGYIDACVTMHYNFP
                     IGVSTVGRVITPAKGKEMILATTTGTSATNRIEAMVRNAIYGIATAKSMGNKCPKVGI
                     LNVDGARQVEKCLKELKDNGYDMEFADSIRADGGCVMRGNDLLVGAPDVMVTDTLSGN
                     IFMKVFSSYTTGGDYEAQGFGYGPGVGEDYDRKVLIVSRASGSPVVANALKYAYDVVK
                     GDISNVARNEFAKVKKAKFDDIISSLTKKEVKAEKVEVKMPDKEIVTRQIAGVDIMDL
                     EDAVSELWKNGIYAESGMGCTGPIVLVNEAKGDLAVETLVKAGYTAK"
     gene            43575..44654
                     /locus_tag="KR231_000337"
     CDS             43575..44654
                     /locus_tag="KR231_000337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HBH0002755.1"
                     /translation="MSRVKNVVELLETKGVDALYLTKKTNVNYISGFPDEEAYAVICK
                     DGNFLVTDSRYMELAEKVCKDFEIINWHNFDRSVAKAVKSVCDKVGIKKLGFERTNIV
                     FDKYEELKNLIEKDNGELIPTENIVETLRYVKDKDEIKNTRKACEIADKALEELIPHI
                     KAGVSEIELATRLEYFMKMNGAQNIGFETILISGAKTSLLHGKPSDKIIEKGDFVLID
                     YGAMYNGYISDTTRTFIVGGASEKQLEIYNLVKEAQNVGVENMKAGVHATIPDAEIRK
                     VVKKYEDYYYQGIGHGVGRDVHEEPFIGNYGDKIIEEGCIITMEPGIYFPGWGGVRIE
                     DTVLITKNGPERLTKFPKDLMILDK"
     gene            44767..45366
                     /locus_tag="KR231_000338"
     CDS             44767..45366
                     /locus_tag="KR231_000338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0002756.1"
                     /translation="MYKKHKFIKNIKKAWYKIKLIDRCLIIVMAILMFQSIYNLFVNE
                     VNSQDTTTIDVVVRTTSAAIFGYFLSANFIKRPLRKYTNTDVSSNLFIDNNLSPKGQE
                     SNQNNIMNVKNTIGFTSEADNYEKKIPINNNEGFEEGETSELQIIIATVICIVALTVL
                     FVVRNFTTTTSASLGTISQMRDFVSGCVGFLLGCPSKPD"
     gene            complement(45553..46425)
                     /locus_tag="KR231_000339"
     CDS             complement(45553..46425)
                     /locus_tag="KR231_000339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HBH0002757.1"
                     /translation="MNINYLYYFQTVCKYKNMTKAAESIHISQPSITLAIKELEKELG
                     FELFYRIGNKIELTPEGKIFLDKSKHFIKQFEDFQCDALDLGKKRKASLKIGIPTVLG
                     TFLLSKILPRFNVIYPDIELKIFEVPTFVGAKMIEESTLDFCIGIIDSDIYDDIDSKT
                     IYKTELYLVTNPKNELAKHPIISNYMLKNVPFVILSEGSYHYKIITKRLEKAKPNIIL
                     HSNQLSTIRYLLENDLASTILYKEIFQNTENLCSIPLERAITANIGVLWRRNQYISHS
                     MKLFIEYMASIHIN"
     gene            46842..48245
                     /locus_tag="KR231_000340"
     CDS             46842..48245
                     /locus_tag="KR231_000340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0002758.1"
                     /translation="MKGSDLVKFELMDFLMNPFVLMFAAVITGILFGKIKFGKFNFGV
                     SGALFTGLFIGWLAYSLGNLIIAKGETAAGYKAATVMMGNGIISSDFFDFFLIIFVAA
                     VGLLAAKDMKAVLKKYGARFVILGVLITFIGGSMTYAMTLLSSDKGSSAYEVSGVYTG
                     ALTSSPGLAAALETAGKHAEDVSKEFEKASIKDKKEILKVVDPEGKLDVNTTTSLTQE
                     QIDKYIAYAEAGVGIGHAVAYPFGVLIVILGVNFLPKLFRMDLKEERRKYEKEMKEAR
                     DSVSGKTIPEVPFNIITFFLTCLAGYLVGGIHVFMGPLGYFTLGATGGSLIVSLVLGY
                     IGKIGVVNFRMEEKVLNILKQIGLVFFLAIVGLRYGGKVVDSIMTSGMHLALVAIAVG
                     VTAMMIGFLVGKYVFKLNWILLSGAVCGGMTSTPGLGAAVDALDSDDPAAGYGATYPF
                     ALLTKVILVIVLHKLPM"
     gene            48272..49816
                     /locus_tag="KR231_000341"
     CDS             48272..49816
                     /locus_tag="KR231_000341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA hydrolase/transferase family protein"
                     /protein_id="HBH0002759.1"
                     /translation="MNNEGAFEELSGRLRNKELCDLIMNADEAAKIIEDGMVIGVSGF
                     TPSGYPKAVPLAVSERAKSGEKIKLTVYSGASLGPEVDGAWSEAGIIERRLPYQTNSI
                     LRNNINKGVVDYIDMHLSHSTQFLNYGTIPKVDVAIVEALAITEEGNIIPTSGIGNSP
                     SFIKSADKVIVEINLAKPMEMEGMADIYITENPPNRKPIEINHPKDRIGTTYIPCGLD
                     KIAGVVITNMQDKTRPLGVVDEASKKISNNIIAFLREEVKSGRLSKNLLPLQSGVGSV
                     ANAVLYGLCESEFENLTCYTEVVQDSMLDLIRMGKVTMASTTSVSPSPEGLIKFEKDI
                     DFFKDKIILRPQEISNNPEIARRIGVIAMNTAIEVDIYGNVNSTHIMGSKMMNGIGGS
                     GDFARNGAITIFSTESIAKNGDISSIVPMVSHVDHTEHDVMVIVTEQGYADLRGLAPR
                     ERAIKIIENCAHPDYKEQLRDYLNRACKSGAKQTPHILDEALSWHSKFMSTGTMKKAE
                     TFKSAL"
     gene            49847..51238
                     /locus_tag="KR231_000342"
     CDS             49847..51238
                     /locus_tag="KR231_000342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldehyde dehydrogenase family protein"
                     /protein_id="HBH0002760.1"
                     /translation="MEKAVENFEDLSKEYINGYIERARKAQREFECYTQEQVDKIVKI
                     VGKVVYYNAEYLAKLAVEETGMGVYEDKVAKNKSKAKVIYNNLKDKKSVGIIDIDRET
                     GITKVAKPVGVVAAITPCTNPIVTPMSNAMFALKGRNAIIITPHHKAIGCSTKTVEMI
                     NEELEKIGAPENLIQILDQQSRENTRNLISSADVVIATGGMGMVKAAYSSGKPALGVG
                     AGNVQCIIDRDVDIKEAVPKIIAGRIFDNGIICSGEQSVIVAEEMFDKIMDEFKNNKG
                     FIVRDKVQKEAFRNAMFVNKSMNKDAVGQSVHTIAKIAGVEIPEDTKIIVIEADGPGE
                     EDIIAKEKMCPVISAYKYKSFEEGVAIAKANLNVEGKGHSVSIHSNTVKNIEYAGENI
                     EVSRFVINQCCATSAGGSFFNGLAPTNTLGCGSWGNNSISENLDYKHLINISRIAYYM
                     PENEVPTDEELWG"
     gene            51431..52927
                     /gene="abfD"
                     /locus_tag="KR231_000343"
     CDS             51431..52927
                     /gene="abfD"
                     /locus_tag="KR231_000343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430738.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxybutyryl-CoA
                     dehydratase/vinylacetyl-CoA-Delta-isomerase"
                     /protein_id="HBH0002761.1"
                     /translation="MALMTGAQYIESLRKLNTKVYMFGEEVKNWVDHPMIRPSINCVA
                     ATYDLAHDPEYADLMTVTSNITGEKINRFGHLHQSVDDLIKKVKMQRLCGQKTASCFQ
                     RCVGMDAFNAVYSTTFECDKAHGTNYHDNFVKYLTYIQENDLVVDGAMTDPKGDRSLS
                     PSAQPDPDMFLHIVERREDGIIVRGAKAHQTGSINSHEHLIMPTISMTEADKDYAVSF
                     AVPSDAEGVFMIYGRQSCDTRKLEEGADVDLGNKEFGGQEALVVFDNVFVPNDRIFLC
                     GEWDFSGMLVERFAGYHRQSYGGCKVGVGDVIIGAAALAADYNGANKASHIKDKLIEM
                     THLNESLYCCGIACSSEGHKTEAGNYQIDLLLANVCKQNVTRFPYEIVRLAEDIAGGL
                     MVTMPSEKDFKSDLKVGTSGMTIGEVCNKYFKASSVASTEERMRILRFLENICLGSSA
                     VGYRTESMHGAGSPQAQRIMISRQGNINQKKELAKKIAGIKKEEALNL"
     gene            53062..53337
                     /locus_tag="KR231_000344"
     CDS             53062..53337
                     /locus_tag="KR231_000344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0002762.1"
                     /translation="MTCGVRFCGGCNPRYERGKALTIIKEHFNGRVDFSIAQENVEYD
                     LLLIIGGCATLCASYQQYKVKNECVKMWDFSHIERVINVIESAICET"
     gene            53361..54668
                     /locus_tag="KR231_000345"
     CDS             53361..54668
                     /locus_tag="KR231_000345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA hydrolase/transferase family protein"
                     /protein_id="HBH0002763.1"
                     /translation="MSWQELYQSKLCSATEAVKQIKNGDTVVFAHCVGEPPALVEAMI
                     ENAEQYKDVEIKHMVSLGSGGYTAKGMEAHFRVNPMFVSGNVRKAIENGDGDFTPAFF
                     HEVPKLLREKRLKCDVVLAQVTPPDEHGYCSLGTSVDYTYEAIKTARTVIVQVNDQFP
                     RTYGEVVHVSEFDYIVEKSQPLFELQPAKIGEVEEAIGKNCASLIEDGSTLQLGIGGI
                     PDAVMLFLTDKKDLGIHSEMISDGTLALYEKGVINGKYKNFDKEKMTVTFLMGTKKLY
                     DFANNNPAVEVKPVDYVNHPAIIMKQHKMVSINSAIQVDLMGQVVAEAMGLRQFSGVG
                     GQVDFIRGVSMGEDGKAIIAMPSITTKKDGTVISKIVSIVDEGAPITTSRNDVDYIVT
                     EYGIAELKGKSLRERARNLINIAHPSVRESLAVEFEKRFKEKY"
     gene            54688..55806
                     /locus_tag="KR231_000346"
     CDS             54688..55806
                     /locus_tag="KR231_000346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxybutyrate dehydrogenase"
                     /protein_id="HBH0002764.1"
                     /translation="MEALRVVPKIFYFDTFKEFNEEFKIGKNDLVITNEFIYEPYMKP
                     LGIDTNLIFQEKFGTGEPSDEMIDSMTKEMKKYNFDRIIAFGGGTIVDICKILALDVP
                     EKSIDLFEGEVSPKKVKELVVVPTTCGTGSEVTNVAIAELKSKHTKKGLAVEETYADY
                     AVLIPETVKGLPYKFFVTSSVDALIHAIESYLSPKASPFTEMYSLQAIKMIMDGYKKI
                     VDKGEEERFNHLRDFVLASNYAGIAFGNAGCAAVHALSYSIGGAFHVAHGEANYQFFT
                     EVFKMYSRKKPNGKIIKCTKILADALECDPNCDVYGELEKFLNKLIAKKALREYGMVE
                     SQIDEFTDSTIANQQRLLANNYVELSREEIREIFANLY"
     gene            56093..57013
                     /locus_tag="KR231_000347"
     CDS             56093..57013
                     /locus_tag="KR231_000347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-bromo-4-chloroindolyl phosphate hydrolysis
                     family protein"
                     /protein_id="HBH0002765.1"
                     /translation="MYKSENFSKKSVLINSFLSKFLKIIGWGLVSLFTLSALVLSTIS
                     IIIGWAVILPIQVCAVFLLIGGVCIFKGKRLGDQISRYKKYCTIINNRNIIPVELIAE
                     NTSKSLNFIIKDVQKMIDKNYFINTYIDKRNNQIVLTNEDFVPPRYEDVAYEVKEEEK
                     TDESNEVDTIINKGMNYLTQIKEANKNIKSESMGDKIVQVEDVTSKIFDVVKHDPSKL
                     TQIQKFMDYYLPTTLKLLNSYHTLEEQGIDRENITTTMESIENTMNTIVVAFENQLDY
                     LFEDEAIDISTDITVLENMLVQEGLTSGKF"
     gene            57128..58285
                     /locus_tag="KR231_000348"
     CDS             57128..58285
                     /locus_tag="KR231_000348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toxic anion resistance protein"
                     /protein_id="HBH0002766.1"
                     /translation="MNNLDDIPVMPTLTLDPFGEESNTNDIDNSDLLMKKDEKDPEEE
                     KLSESERKMVKEFAEKIDITNTNMILQYGAGAQKKVASFSETALKSVKTRDLGEVGDM
                     LTNLVTDLKAFSADEKEQSGFLGIFKKANNKISNLKTKYDSAEVNVDKVSKELQKHQV
                     KILKDIAMLDKMYELNLAYSKELTMYIIAGKQKLKDMKEYEMPKLREKARLSGSTEDA
                     QSVNDMVSLCDRFEKKIHDLELTRMVSLQMAPQIRLVQNSNNLMAEKIQSTIVNTIPL
                     WKNQIVLALGISHLNQAMKAQREVSNMTNELLLKNAETLKMGTIETAKESERGIVDID
                     TIKKTNQSLISTIDEVVKIQHDGRIKRQEAEVELSKIENELKSKLLEFTVK"
     gene            complement(58366..59262)
                     /locus_tag="KR231_000349"
     CDS             complement(58366..59262)
                     /locus_tag="KR231_000349"
                     /inference="COORDINATES: protein motif:HMM:NF033516.0"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HBH0002767.1"
                     /translation="MLKKVKYPIGQVKVSDKFKTIKLLSRKYSISSMCKLISVSRSGY
                     YKWLSYSKKSSDRGIKDRIIKDYIIEIHKKYRGTYGRKRICTYLNKILDTPINHKRVY
                     RLMKELGIKSIIRKKVYRRKFKSYEIYDNILNREFRANQPLEKICMDITYIPIGKKFL
                     YMNVAKDLFNGEIVAYEISTKMDTKLVNNTVNQLINMNLAKDCILHTDQGSQYTSRSY
                     SKRLKDNGIIQSMSRRGNCWDNAPIESFFSHFKSELIYLIDTTDPKEMISLINDYIYF
                     YNNERIQLKNGMSPIEYRTHSE"
     gene            complement(59220..59537)
                     /locus_tag="KR231_000350"
     CDS             complement(59220..59537)
                     /locus_tag="KR231_000350"
                     /inference="COORDINATES: protein motif:HMM:NF013677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HBH0002768.1"
                     /translation="MSKKHKKYSKELKLKAVNLYIKEGYSSYKIAEMLNIRSKTQVQN
                     WVKDYKNKGKTAFDDETRGRFKNISLENDNRKFKSVEEELKYLRMENEFLKKLSTLLD
                     KSK"
     gene            complement(59674..61173)
                     /locus_tag="KR231_000351"
     CDS             complement(59674..61173)
                     /locus_tag="KR231_000351"
                     /EC_number="1.1.1.205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IMP dehydrogenase"
                     /protein_id="HBH0002769.1"
                     /translation="MAFYFDTPSHTFSEYLLVPGFSSTDCIPANVSLKTPVTKFKKGE
                     EADIYMNIPLTSAIMQSVSDDKMAIALAKEGGISFIYGSQTIEDEAAMVARVKSHKAG
                     FVVSDSNIKPDNTLKDILDLKEKTGHSTVAVTEDGTSTGKLLGIVASRDYRISRMDLD
                     TKVSEFMTPMSSIVYANKDVTLKEANNIIWDHKLNSLPVLDDNGNLMYMVFRKDYSSH
                     KENPLELLDSSKRYVVGAGINTRDFAERVPALVEAGADVLCIDSSEGFSEWQKITLDF
                     IREKYGDTVKVGAGNVVDREGFLYLAEAGADFVKVGIGGGSICITREQKGIGRGQATS
                     IIEVAQARDEYFEKTGIYIPICSDGGIVYDHHITLALAMGADFIMLGRYFSRFDESPT
                     NKVNINGSYMKEYWGEGSARARNWQRYDLGGDKKLSFEEGVDSYVPYAGSLKDNVTLS
                     LSKVRSTMCNCGALSIPELQKNAKLTLVSSTSIVEGGAHDVMLKDNRNL"
     gene            61769..63193
                     /locus_tag="KR231_000352"
     CDS             61769..63193
                     /locus_tag="KR231_000352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannitol transporter subunit IICB"
                     /protein_id="HBH0002770.1"
                     /translation="MSSSNQSTIKTSIQRVGKFLSGMVMPNIGAFIAWGLITALFIPT
                     GWMPNEKLSTIGDPMIKYLLPLLIAYTGGKAIAGQRGGVIGAAAAMGVIVGADIPMFI
                     GAMIMGPFAGWVIKKFDKFVDGKIPTGFEMLVNNFSIGIIGMLLAILGFYAIGPAIVA
                     GTALIESGVQFIVSKSLLPLVSVFIEPGKVLFLNNAINHGILGPIGIAEAKEAGKSIM
                     FLLESNPGPGLGVLLAYWMFSRGSVKQSAPGAVIIHFFGGIHEIYFPYILMNPVLILA
                     TMAGGAAGILTFSILGAGLVAAPSPGSIFALMALAPKGGLLPVLAGVAVATVVSFLVA
                     APFVKRASANESEEDSTSLEEAKAKMSDMKSASKNSEKNIEKKQLEVNEIKKIVFACD
                     AGMGSSAMGASRFKNRIKNLDLDIEITNSSVDNLPDDTQIVVTHNTLVERVAKNNSSV
                     EIVSINNFLNDPNLDTLFKRLESK"
     gene            63228..65357
                     /locus_tag="KR231_000353"
     CDS             63228..65357
                     /locus_tag="KR231_000353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HBH0002771.1"
                     /translation="MKKKKITSRQKKIILMIVENSKKNIPITISEIAGTLELSSRTVL
                     RDMSGIEKWFDENDFNFVKKPGVGLILEENIENQNFIIELLEEEKIEKEYSKEERNLI
                     ILSKLLVSNEPVKSYYFAKILKVSEGVLNNDFSLASKWLERFDIELVRKPGLGVYLKG
                     QEKSFREAYVNLIYDSFNEKEILDMVRNISENIQTDKAIEILSENRLLNLMDRCIIIK
                     VEATLTKKLSDLDVNLADSAYIGLVVHISLALQRIKNGENITMDKEFLKELSITEEFK
                     LAKEIVKGMETDFNMDIPVDEVGYITMHIRGAKQRSSSNHKALNLDDIEIMEITNKMI
                     DLAEDEFKISLKNDERLFKDLANHLGPSINRLNMGLEIRNPLLDEIKSKYSYAYDGVE
                     KISRIIKDKLNINSIPESEIGYIAMHFASAIEKNLMMNTNINIVVACPTGIGTSRFLS
                     TKIENKFPNLNILETISAINIDEEYLKGKDVDLIVSTVELNTSLNYICVGPFMSLDDE
                     QIIKEKIKSIAQNKLINLNTKNDTKSKNKVYEQITESMNIGKDILQFLEEIRFEKFES
                     KDLSELIEDSSKIFAKSSEDIMSIKESLKERLKISIPYIEESKILLLHCMSERIDIMK
                     LSIIKLENRIVLDSNEEIDNVVFMLLPKNSPSYQRQIMSEISGSLIDNIIFTNKINKF
                     SIEEMTLEVKDIVFNFYTNRLKAFIDE"
     gene            65387..65809
                     /locus_tag="KR231_000354"
     CDS             65387..65809
                     /locus_tag="KR231_000354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBH0002772.1"
                     /translation="MSKVLNENNIFLGLDSVSKEEAITLAGRKLVENGYVKEEYIPAM
                     LEREKVMTTYMGMGVAIPHGVNEAKKEILSSGIVILQFPNGIDFDGEKAYLLIGIAGV
                     GDEHLEILSNIAVVLDDDLTERLKNSNDKQAFMEAFAK"
     gene            65828..66979
                     /locus_tag="KR231_000355"
     CDS             65828..66979
                     /locus_tag="KR231_000355"
                     /EC_number="1.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannitol-1-phosphate 5-dehydrogenase"
                     /protein_id="HBH0002773.1"
                     /translation="MKKAIQFGAGNIGRGFIGGLLVKSGYHVVFADVNEEILNSINKD
                     KKYTIHIRDVECIDEVIDNISAVSSIKEEIIDEIVQAEIITTAVGPLVLTKIASTIAK
                     GIKARKEKGLTSNLNIIACENAIYASSSLKEEVLKYLNKEEVEYLEIYVGFPNCSVDR
                     IVPPGKNENPLDVTVENFYEWNVEKQGFKGEIPTIVGMNLADNLMAYIERKLFTLNTG
                     HAITAYIGYLKGYKTIEESIKDKFICDIVKSAMVESGEGLIKKYNFDSEAHYKYIDKI
                     LNRFKNPYLNDDVLRVGREPLRKLSDKDRLIKPLMTAKSYGLSVDNLILGIGAALHYN
                     NSEDTQSVELQELIKSNGVKKAVAKIANISNDEELLNNIEKSYIFMKNL"
     regulatory      67085..67186
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00167"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="purine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="guanine and/or adenine"
                     /db_xref="RFAM:RF00167"
     gene            67369..67941
                     /locus_tag="KR231_000356"
     CDS             67369..67941
                     /locus_tag="KR231_000356"
                     /EC_number="2.4.2.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xanthine phosphoribosyltransferase"
                     /protein_id="HBH0002774.1"
                     /translation="MKALQEKILREGSVSGNDILKVDSFLNHQIDVAFLNEIGREFKE
                     RFKEEKVDKIFTIEASGIAIASIVSQYFDNAPVVFAKKSESKNLDKDVYETNVYSFTK
                     AREYSVKVSKKYINKGENILIVDDFLANGRAALGLKDLIEQAEANLVGVGIVIEKGFQ
                     AGGALLKANDVRLESLAVVESIDNGTVKFR"
     gene            68005..68655
                     /gene="fsa"
                     /locus_tag="KR231_000357"
     CDS             68005..68655
                     /gene="fsa"
                     /locus_tag="KR231_000357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-6-phosphate aldolase"
                     /protein_id="HBH0002775.1"
                     /translation="MIFFIDTANIEEIKEANDLGVICGVTTNPSLIAKEGRDFIEVVK
                     EISEIVDGPISAEVISLEHEGMIEEAEKLSKIHKNIVIKIPMTAEGLKAVKVLSSKGI
                     KTNVTLIFSAGQALLAARAGATYVSPFVGRLDDISQNGLDLIEEIVDIFSVNSIEAQI
                     IVASVRNPIHVLQAARMGADIATVPLKVINQMIKHPLTDKGIDSFMKDWEGASLKL"
     gene            68807..71731
                     /locus_tag="KR231_000358"
     CDS             68807..71731
                     /locus_tag="KR231_000358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HBH0002776.1"
                     /translation="MDKILREIQREDKKNPYTDQELAEMLNVARSEVISVRKKNNILD
                     SRERRKKILIKDISKIVSENPQMSERKITEILIENGYNISRSAVSKLLKEENLNQSKI
                     GIKDKEPASSGKYVKVSKVVEEDGFEELIGIKGSLKEKVNLAKSAIMYPPNGLHTIIY
                     GETGVGKSELATCMYKYAIKNNIKEENSPFIVFNCADYAENPNLLIAQLFGVVKGAYT
                     GADANREGLVEQANNGILFLDEIHRLPAAGQEILFSLIDRGEFRRLGESSSNRKANVL
                     IISATTENPDSNLLQTFRRRIPMVINLPNMSERPKSERYEIIIKFFEREAKRVNKNFI
                     ITKEVMCALMNYKCTGNIGQLKSDIQVTCARAFSKSIFSSDKVIIDLDSLRDYIKSGY
                     YDCNCKNEKYSEFSVEDIYIDISELVSGKNRILSDNEISEIYNYAEKELKVLESKCFS
                     EEELKNAFIEKLDKKFNAIKNNKNLSDRRSRIDWGGQLKESTLEIMDKVIVFIKEQFK
                     HVNQGLYLALAIHIEHAIGRIKDGKTIINPSLDKIKASMPMEYELSRYIMGIVEDLTQ
                     VTFPEDELGYLAYYINKFCYNEESIKDKVKVVIVTHGKVGIEMSKVVNHILGIECTLG
                     IEIALTDSPSEGIEHVLEELQKIEARKGILVLIDMGSLVILGDEVEKRLGIRCKTVNR
                     VDTLLAMEAGKLATIEGKSLDGIIADLKKNKNYAMINTNKFSYRKNEYGKKNVIITLC
                     LSGVGTALNLKEHIEKQIKEYDTLIEVKPVAFLNNNLEEELNDIEAEYNIIAICGTID
                     IDYKNVPFISYNEVLGKNGINKVLEHLNSKQPVLNIENQLNNLIHEDLILYNFEGISK
                     EYIIDTLVSKLEEGGYVDSKYILSVYKREAMGSVVMASKVAVPHGLPENVIKPAIAIA
                     RLNKPIVWDNKFMVDLVVLLALKENNKKEIRSLFSKINDQHTLEVLLNTEDKNEIKEL
                     LS"
     gene            72308..72766
                     /locus_tag="KR231_000359"
     CDS             72308..72766
                     /locus_tag="KR231_000359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBH0002777.1"
                     /translation="MEFINFVSDKVIDLKMDCKTKEDFFKEIHNKVFDLGFVKEEFGE
                     KILARENVFPTGLNLGDYGVAIPHTDAEYIKEQFISVCTFNEPVVFSSMEDQDEKVPV
                     NLAFVLGLNQPHSQLSVLTELMGIMQNKELVDKLMSSTDKEEVLKTLKSL"
     gene            72827..73102
                     /locus_tag="KR231_000360"
     CDS             72827..73102
                     /locus_tag="KR231_000360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBH0002778.1"
                     /translation="MKKILVACGAGIATSTVVCDKVERLVKENNIQAEVIQCKIAECA
                     TKQEGADLIVSTTILPTTYNIPAIKATAYITGVNTAALDKKILDALK"
     gene            73161..74435
                     /locus_tag="KR231_000361"
     CDS             73161..74435
                     /locus_tag="KR231_000361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012951111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS galactitol transporter subunit IIC"
                     /protein_id="HBH0002779.1"
                     /translation="MDKLLAVVQYILNMGPTVILPITIVVLGMIFRIKFTKALKSGLT
                     IGIGFVGINLVVNLLTSTLGPAAQGMVERFGLNLTVIDVGWPTTASATWASPVAPILI
                     PVCLLVNLLLLYFNKTKILNVDIWNYWHFIVAGAVGYIVTGSYVWAIFCAILMELLVL
                     FIAEKTAKNVQEFYDLEGIALPTGSTASFAPLGYLVGKFVEKIPGINKIQADPDSIQK
                     RFGIFGEPMMMGIILGIILGALAGYDVAGIFNVGISMGAVMLLMPRMVRILMEGLIPI
                     SESIRDFLQAKYGDRELYIGLDAAVATGHPAVISTALILVPITLFLAVILPGNKVLPF
                     GDLATIPFYMAFIVCFRKGNIVQSVITGTIVIAISLYMATNFADVHTQLLQQANMMPE
                     GTTMVTSIDTGGNLLKWGILKLSQLVSSFGIF"
     gene            74565..75617
                     /locus_tag="KR231_000362"
     CDS             74565..75617
                     /locus_tag="KR231_000362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactitol-1-phosphate 5-dehydrogenase"
                     /protein_id="HBH0002780.1"
                     /translation="MKAAVLHGTNDMRFEDIEIKPCESDEVKIKVMAAGICGSDPPRV
                     LKHWKYPVPAIPGHEFSGVIAEVGKDVKNVKVGDRVVAIPFIPCNECEYCKRGLFSLC
                     DDHGMLGAKSFGAFAEYVNIKATNVLPIGDMNFEDAAMIEPLAVAMHGVLNIGVQVGD
                     TVAVMGSGTMGQLVIQGLKIAGAGTIIAVDISDNKLRESKELGADIIINAKDINPVEK
                     IKELTGGKGVDIALECAGSKITQEQCLLITKKKSKIGFLGIAYSDITLSEEAFENIFR
                     KELELKGFWNSYSAPFPGQEWTKGINLVNEGKIKLKEMVSHRFSLEDTYKAFEMIRDR
                     KEEFNKILILPQGVEK"
     gene            75617..76648
                     /locus_tag="KR231_000363"
     CDS             75617..76648
                     /locus_tag="KR231_000363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012986518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-binding dehydrogenase"
                     /protein_id="HBH0002781.1"
                     /translation="MKAVVKTKPGYDNVEVLEVEEPKATGDKVKIKVEYSGICGSDIH
                     SFKGEYANIKAPVTLGHEFSGIVVEVGEDVKNIKVGDRVTSETTFATCEKCIYCETKD
                     YNLCPTRKGIGTQVNGSFAEYVLSREESIHVLPENVSLLSAALTEPLACCVHAALEKT
                     TIESSDTVLIIGPGPIGLLLAQVVKSQGATVIMSGVTKDKERLEIAKNLGVDRTVNVM
                     EESLADVVNEMTDGNGVNKGFDCSGFMPAVNEALRLLRKKGTFVQVGIFAKKLNEMDQ
                     EAIIQRELQYIGSRSQKPSSWITALDLMANGKVNTEALVTRTVGLDEFKEGITALMNG
                     EEIKVAVKS"
     gene            76740..77552
                     /locus_tag="KR231_000364"
     CDS             76740..77552
                     /locus_tag="KR231_000364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HBH0002782.1"
                     /translation="MSTLRDHSNNIRKNIIKMVAEAKSGHPGGSLSIADMLTVLYFDK
                     MNVCAENPKMADRDRFVLSKGHAAPALYATLAEKGFFPEEELITLRKFGSKLQGHPDM
                     KKVAGIDMSTGSLGQGLSAANGMALAGKLDNKDYTVYTILGDGEIQEGQIWEAAMTAS
                     HYKLDNLIAFVDLNGLQIDGSNEEVMNVSPVDDKFKSFGWNVIVINGHSFEEIGNAVD
                     EAKKVTGKPTVIIAKTVKGKGVSFMENNAAWHGTAPNAEQAEQALKDLEGGL"
     gene            77555..78475
                     /locus_tag="KR231_000365"
     CDS             77555..78475
                     /locus_tag="KR231_000365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase family protein"
                     /protein_id="HBH0002783.1"
                     /translation="MGIATREAYGQVLKELAENKDIVVLDADLGKATKSISFKEVAPD
                     RFFDMGIAEGDMIGTAAGLATCGKIPFASTFAIFAAGRGYEQIRNSVAYPNLNVKIAA
                     THAGVTVGEDGGSHQAIEDISLMRGIPNMVVLNPADALEARQAILTSIDYNGPVYIRL
                     GRAATPDVNSENYKFEIGKGTVLREGSDITVIATGIMVAKALEAAEELAKEGINVEVV
                     NISTIKPLDEALIKETAKKTGKVVTAEEHSIIGGLGSAVCEALAETKDVVVRRIGVKD
                     VFGQSGTPADLLKHYGLTTEDIVKNIKELL"
     gene            78650..79096
                     /gene="rpiB"
                     /locus_tag="KR231_000366"
     CDS             78650..79096
                     /gene="rpiB"
                     /locus_tag="KR231_000366"
                     /EC_number="5.3.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430700.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose 5-phosphate isomerase B"
                     /protein_id="HBH0002784.1"
                     /translation="MKISIGCDHGGYELKEYIKENLINKGIEVEDVGTNSKESVDFPI
                     YAKKVSQNVQSKKSDLGILCCGTGIGMSIAANKFKGIRAAVVSDCFSAKATREHNNTN
                     VLCLGERVIGKGLAMRIVEEWLNSSYNGERHARRLQMIDDIEKENL"
     gene            79126..79791
                     /locus_tag="KR231_000367"
     CDS             79126..79791
                     /locus_tag="KR231_000367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribulose-phosphate 3-epimerase"
                     /protein_id="HBH0002785.1"
                     /translation="MSIICASIMCADQMKLKEELEALEEAGVKLLHCDVMDGIFVKNL
                     AMGPELLKSISENTTIPLDIHLATETPDKYIDMMSYIKPKYISFHVESSTNVKADIQK
                     LRNYGIGPVLAISPQTSVDKIEEYISLVEGILVMTVNPGFAGQKFNLSVLDKLDKLTE
                     ILKDYDNPPFIEVDGNINKDTIKLMNGKKVDIYVVGTSALFNDKPPISYKDKIEELKE
                     SIK"
     gene            79901..81403
                     /locus_tag="KR231_000368"
     CDS             79901..81403
                     /locus_tag="KR231_000368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomannomutase/phosphoglucomutase"
                     /protein_id="HBH0002786.1"
                     /translation="MGDLYKLQNGTDIRGIAYENDSKEVNLTVEEVKKIAKAFHIWLK
                     EKTKKDKVTVAIGTDSRITGSQFRSTVIETLTNDDCNVIDCEIATTPAMFMTTIMDGY
                     NSDGAIMITASHLPYYYNGLKFFTESGGLEKTDIKEMLDIAVKNDSVDYEEVNKKGEV
                     IVKNLIEDYSNLLIDKIRKGVNSSKNYEKPFSGLKILVDAGNGAGGFFAEKVLHILGA
                     DTTGSQFLNPDGMFPNHIPNPENKEAMESICKAVLDNKSDLGIIFDTDVDRAAIVGKN
                     GKPINKNALIAVISSIVLEEHPKTAIVTDSITSEGLAKFINELQGRHHRFKRGYKNVI
                     NEAIRLNSEGEECHLAIETSGHAALKENYFLDDGAYLIAKILIKVAKLSLEGKTIEEL
                     IENLEEAQEEKEVRIGINKEDFRTYAEDILKDLDSHVKSIDGWSVAPNNFEGIRVNCD
                     ESNGDGWFLLRISLHEPLLALNIESNKIGGAEQIYSKLKLFLEKYDLKGL"
     gene            complement(81715..>82758)
                     /locus_tag="KR231_000369"
     CDS             complement(81715..>82758)
                     /locus_tag="KR231_000369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HBH0002787.1"
                     /translation="LSMYNKKTINKKLAIVFLISIVVQAIIQYLVLIFFMYIYYAEAI
                     AIVILFTLVNTVFHFYIYNFLSVKFNYINNISKNIKNIENGNLKYKLEVIGDDEISTL
                     AKSINNITGGLETAVDANIKNERMKAELITNVSHDLKTPLTSILSYVDMLKNNDFDRE
                     TINDYINILDKKSQRLKLLIDDIFEASKLSSGDVEFNITKTDIRELLIQSIVEFEDKI
                     QNSSLDFIIETPEYAVFTMIDGKKTWRVFENLICNILKYSMPNTRVYIDMFIKEENII
                     LTFKNISNDKLNLKPEELIERFRRGDISRKTDGSGLGLSIAQNIIELENAHMEIIIDA
                     DLFKVMLTFRKVN"
BASE COUNT        32593 a         9066 c        14830 g        26269 t
ORIGIN      
        1 taaagaactt tattagtaga tattaaaagc acattttttt ataaaagtac ttttttataa
       61 tttatgaaag gtataattat aaaagtctta ttcaataaaa tttataatta atttagatat
      121 atttgtaaat aatcagtata aaatagatgt tttaatatca taaaggcata attagaaggt
      181 tattaaaatt tattagatat tactctagtt tattttaaaa aaaagtatta taatattcct
      241 tgtgtgaaaa tataggaatt tttattaaat agttttaatg tgtaaataac attctacact
      301 attgtaatta aatatgtaaa aagtaaaata tttaaataga tatattttaa aatctaactt
      361 ttaatattgt aaaaaaatta gaaatttaac aaaaagtaca aaaattcaca tttttttcat
      421 aaagtgtttg actaaaaaat tcacatgttg tagaattaag gtagcaggag ttttgaggga
      481 ggtgtaaata atgataagaa aaataccaca agcagaacta aaagtaatga aattcatttg
      541 gaaagtagat gttacagtga catcaaaaga tgttattgaa gctatggaac aaaaatatgg
      601 ctggaaacaa accaccacac tgacactttt atctaggctg gtaaaaagag gattcttaga
      661 tgctcaaaaa atagacagat atacacatta cacaataaga gtaaaacaca aagattattt
      721 aagttttgag acaaaggatt tcctaagtaa tatacatgat gactctttaa gaagcttaat
      781 ttcagcatta catgatgatg aaaatatagg taaagataag ctagattttc tagaaagtta
      841 ttttgataat ttaaaggatg aataattata tgctatatgt ttttgaaaat cttataaaga
      901 caactattgt atgtagtctt ggtatttgtc tattattatt tttgaaaaga tatttattta
      961 agaagtttag taagagattc aattattata tttggttgat aatagtcttt agaatgttac
     1021 tttttctatt taattataca atagtgtatg aagtaaaaga acccaaagaa aatgcattag
     1081 gaaataatat tacacaaatt gatatttcta cagataataa tcttatgctg tatgtagctt
     1141 atttatggtt atttgtaact atagtcattg cagtttatac atttataaag tatacaagat
     1201 ttaaaaatct agttgttgat gtatcttatg atattgaaga taatgatata aactgtatct
     1261 acaaaaactt gttaaaagaa ttaaatataa aaaagaaaat tgaattaaga ggttctgatg
     1321 aattgataag tccagcaggt atgggattat ttaaatctta catattctta ccagactatc
     1381 cttatagtaa agatgaacta acttggattt tgaaacatga attaatgcat tttaaaaata
     1441 aagatatttt aataaagttt ttagttttgt ctgttagaat aatatattgg tttaatccac
     1501 ttgtatatgt aatgagcaat aaagtaaatc tagattgtga attatgttgt gatgaaagtg
     1561 ttttggtaga atgttcttta aaagataaaa aagaatatgc actagcactt ataaagtcaa
     1621 ttaagtttag taaaaattat aatagtaaga ttttgacaac cgagtttgat aagacaaatt
     1681 tggaaaagag acttgagagt attgttaaaa agaaaggcaa aagtggaata ctaattgctg
     1741 ttttagtatt tatgacttct ataacatctt ttgttgaagt tgatgctcaa gttagaattg
     1801 atgagggtaa taatggaatg aataacaata ttaatgaatt tttattgaat aagacgactg
     1861 ataaaattat aaatatttat tataaagatg caccaaatga aattaggaaa ttttatgaag
     1921 ataaatgcga attagaaggt aaaataccta gagactatga cataatagaa atggatatga
     1981 aagattataa tcaattaata aaataattat aaggaggatt ttatgttaac aaaattaaga
     2041 aaaatagtag ctattatgtg ttgcttattg cttactttta caagtgtggc atttgctgac
     2101 acaagtaaag agaaaggagg aagtaaagag actgttccag agaaaaacct agattctttt
     2161 actctttctg ggtatatata tacatatgaa aatgcgccac aagaaataag agatgaacat
     2221 aaacaaaatt gtgaagagat aaatatagac cctaagccag atgatgagat atttgttcca
     2281 gaatcagcta atctaatgaa tgaggacaat agtaaaggtg tttatgcaag ttatactgtt
     2341 tcttataata taggtgctaa aactataaca attatgagta atgagtattt gactataagt
     2401 acaacaaaag ttatacgaaa gggtaatagc ggaaaagaag taaaagctgc acaaatcatg
     2461 ttaactttac ttggttataa tgtaggtata gatagttctt ttggaagtaa gacatataat
     2521 gcagttgtaa gtttccaaaa aaaatacggt ttgtctgcag atggaataat tggtccagct
     2581 acttgggata aattgggtag actaactgac cctactcttt cataggatta aaatctaaaa
     2641 atatattaaa tagtgtctca atatgatttt tcaatttaaa tgagacacta tttaaatata
     2701 aatgttataa aactatttta caataaattc catataactc taccatctat atccttaaca
     2761 ttttgacaac cagtcaaaat catagtctca cataactcat tcctaacctt ctctataaaa
     2821 aactccacac catcaagacc accgccaaaa gaagcagtaa caaaaggtct tcccatcaaa
     2881 acagcatcag cacccaatcc aagcatctta actacatcaa caccagtcct aactccacca
     2941 tcaacaagta ttgttatctt tccctttaca gacttagcta tatctggaag tacctcacaa
     3001 gtaccaggag tataatcaag tactcttcca ccatgatttg aaacaataat ggcactagca
     3061 ccagactcta cagccatcaa agcatcatct acagtcataa ttccttttat aataaaaggt
     3121 aatctagtgg attcaaccaa ttctctaatc tcatcaattg ttttaggaga aaaaggattt
     3181 tcttgaaatt gattattaat aagtccacaa gcatcaaggt ctacaccaac tgcaaaagca
     3241 cctgcttctt cagacaatct aattttatct attatctttg aattattcca aggctttata
     3301 aatacaattc catttcccct attatccttc aatacatcta aattatccag taaaaaagta
     3361 tctacattag tatcgccaac catagcataa attccagaat tagaacaacc tctaacaaca
     3421 ggctctatgt attctttttc ggaaacttta ccacccatgt tcaatatagt acctgataca
     3481 ggtgcagcga atataggaga actcattttt ctaccaaata attctatgga tgtatctggc
     3541 tttgaaacat tatgtatgac tctcatattt atctttattt tttctagact ttttctattt
     3601 tcaatgaaag acgaaccact tcctttacca cccataccag gaacatctcc agcacaagct
     3661 aatccattac aaattttaca tactttacat gttccattaa agttctctct agctgatttt
     3721 agtaagtcat tgtaatccat acaaaatctc tcctttttat aatattaaaa ttgagtatta
     3781 ctatattgaa aatatcttaa ttgtaaatat agggatgtta ttatgatgag ctaaactaga
     3841 taatacatat tagatatttt ttattgttgt agatagttaa attatatcat attagatagt
     3901 caaattttga aaaaaactaa cttatttaag tatacatttt gaaaaaatta aaaaagctat
     3961 atatagattt ttaaagaaat ctatatatag cttttaagtt tatgtcaatc ttttttgtta
     4021 atgaataaat aatatagaat acaatataca aaaaagtttc ttgaaatgct aagataatcc
     4081 ccatttacaa agcaacatca ttatactgtg taaatttgaa tcaacaatgt tttcaccata
     4141 tttcatcata aaatcctcta attgtgtgtc aataaatgaa taatatccac ttatactatc
     4201 gatgtatgca gtcattaagt gtatacattc atcactttta tctttataca tatatatctc
     4261 cccctatata caatatataa atttagatac caaatcgtat catattaaat agttaagtgt
     4321 gtaacatcta tgcagttata tatttatatc attatattaa taactaaagt gagttttgac
     4381 aatagatttt gggaaactgg atgttcaaag tgcaaacttg gattttaaaa tcattaatta
     4441 agatagcgca taggaatata tgtatacata acttaattat aaagattata aacaattact
     4501 tttattaact ttatttaaat ggtagaataa cttggagatt aataattata aggaggatat
     4561 aatatgagtt tatataagtt tatatatgat gataaggaat atttattaaa agaggagaac
     4621 tgtagtgctt taataaatga tgaagaaaat ccagttcaag gagtaagtat ttcaaaaata
     4681 attgatatac ttaatgaagc agaagaagtt gattttgatg tagaatatta tcaagaagca
     4741 tgtccattat gtttagaagg agtaaaagaa aagaaaaaat tctttccttt tttagaatat
     4801 cacttttata ttttcagtaa agatggagaa tatgtaataa gcaatatatc tgttgattat
     4861 aaaggactat cttttaataa actatcaagg gcaaataaag ttgataatag ttatattgta
     4921 agtgtgataa tttgcgaaaa ttgtcaggat tatatagttc agatagaaaa ttgtatagtt
     4981 tagtgtaaag tatgtcttaa tttaagagaa atttctaaat tgagacatca acttttttca
     5041 aaaatagtat ggaaaattac taaatttatg agataatgta agtcggaggt gagttacaat
     5101 atatagtaaa tatttggaag agatagatga tacaatttta gattcaatgt ttaaactaac
     5161 cttgaatgaa agattattga ctaataacga ttttattgaa aataaaattg atgtagtaaa
     5221 gaatttaatt gattgctata aaactgaaca aaatagttta atgttattaa aatcaaattt
     5281 tttgctagct ttattatatg gtattcaagg gtttagtgaa aaaatgaaag agtatatttt
     5341 gatttcctgt aaatatattg ataaatgctt acccaaagat tataaatttt tagcacgatt
     5401 ttattcacaa atagctattt taagtttaaa aaatgaagat gtaaataagg caaatttata
     5461 tatggataaa tttaatctta tttgtgatga aaataatttt ctaattgaag aaattatttt
     5521 taaatcacaa cttatttaca ttaaggcaag taagtgtata gaatcttctg taataattaa
     5581 agagatagaa acgttgtata taaagataaa agaaattaac gattttaatt gtaaaaaaat
     5641 atattttttt attattggta aaatatattt tttgtttttg gatgatgctc taattgctaa
     5701 ggtaaatttt ttaaaagcaa gaaaatatgc agatttacta aaggatatgc aagtatcttc
     5761 actatgtaat ataaagatag gtgagtgtga atgttcgttt gaaaattatg aatgttccat
     5821 ggaatatttc aatgaagtaa taagcaataa aaagtataga aatgtaaata taattcaaaa
     5881 atatagagca tcaaacaaca taactaaaat attaataaag actagaaatt atcctgtcgc
     5941 aataaataat ttagcaaaat ctgaagtata tctagaaaaa attaaaaatc atagcttaaa
     6001 agaagtagag aagtttgatt tatttataag tttagccatg tattatgcaa aaagtaatga
     6061 aaaatctttt gaacaatcaa tatgctattt agatagagct aaaaacatat taaatatgat
     6121 aaaaaatata gaagaatata taatatatga tttagaaata atttatcacc aggcaaagat
     6181 atattatatc tttggatatt atgataatgc cttaaacaca aataaaaaac tccttgaaaa
     6241 atctaaaaat gctaaaaatt ataattatgt gaagttagca tacaagagta tatatttgtg
     6301 ttttgaaaag attcaaaatt atgaaatgag tatgaaatac tttaaaatgt attatgagtt
     6361 aaaaatgatg tatataaaag ctcgaaatag aaattatata gattccttaa attatagaca
     6421 tgagtatata gaaaaagaaa taaataacat gagaaaagta aaacttgatt tagataaaaa
     6481 aaagtatgtt gaccatttga caagtgcata taatagaact tttttgaacg attttttaga
     6541 aaaacaagaa gttagtgaat attgcacagc atttatgata gatgtagatt actttaaaga
     6601 atacaatgat acttatggac actataatgg agatattgct cttaaaaata taactataat
     6661 aataaaaaaa tatctaaaaa aagacatgct tatgataagg tatggtggag aagaatttct
     6721 gatattatct gtatgtaaag attataaaaa aagtaaaata tttggaagaa aattatgtag
     6781 gattgtaaag aaatttttaa acaataattt gacagttagt attggcattg atacatgtaa
     6841 aaatagtagt atagatataa aagaaataat tgaaaatgct gataaagctt tatataaagc
     6901 aaaggaaagt ggtagaaata gatgtttgca ttatcatgat tttaagaatt tttaactgtt
     6961 gaaataggat tggtgattta cttgaaaagg agtttaatag aagatttaaa gagaaatata
     7021 aacaagatag aatacgatat gttgactaaa ttctatctaa atttgacaga tttaaactac
     7081 atcttggatt atcacaaaga ccttttaaat acaaaattag aagataatag tagagtctat
     7141 actttatatt taattagtct tataaactat ataaaaaaag atagagaagc atcatacaac
     7201 tatttgatag agtcattaaa gtatattaaa aaattgtcat taaaagatga ttcagatata
     7261 atatctaaaa tttatattta tcttacttta tcagctattt ctataagaaa atatgataag
     7321 gtaaataatt tttatttctc agcaaaaaaa attataagac aaaatcattt aaatgagttg
     7381 ttggtattgt taaatatgag tttatgtgta gaaataagtg ctttatatca gaccaaaacg
     7441 gatgtaatag ctttagtaga agaagtgtct ttttttaaaa ctttaaaaaa taaagctctt
     7501 gtaagtaggg caaattatat atttgggaga gtttatctat atttatttaa taactttata
     7561 aaaagtatgg aatacttaat tgaatgtcta aaattggctc aagaaaataa tttatactct
     7621 atagaggctt tttgtaaatg tataataagt ttgtgttatt tagagagtgg aaataatgta
     7681 gaagctataa aatacataaa taatgtatta gatgttgcac acagtaataa ctcaatatca
     7741 gtaactgaaa gagtgtctat aaaaatagac cttatatggg catatttaaa agaagatatg
     7801 aataaagaag cagaagttat tttattaaag actataaaat taatgaaagt tgttgaaggt
     7861 gtatataagg attatttata ttcatttata tttttatatt cagctgaaat tgagttaaag
     7921 aaagataatt gtagttttga aaaggtaaac acctatttaa ttttatcaaa aaatatatat
     7981 aaaagttttg gagatgtttt tatatataat tctaaactag attacatata taagttgtat
     8041 ggagatttat atataaaatt tggtaatata gatgaaggta taagttgtta tataaaaggt
     8101 ttaaatttag ttaaaaagag ttcattgaat cttagaaaaa tatctatatt ttatgggcta
     8161 atagcaaatg gatatgagct aaaaaaagat tttaaactgg caatagaata ttataaaagt
     8221 atggattggt attctgatag gtgggaaaaa aataattcct ataaaacatc tcaagcaatt
     8281 cacaaacaat atgaactcag acaaaaacaa gagagtttaa gattactagt ggatgataat
     8341 aagaaattag aaaatgatat tttaaaagat ggacttacta aactatataa tagaagatat
     8401 ctggaacagc agttggattt atttaatgaa accagagaca aaaatatggt cgcaatactg
     8461 gtcgatatag attgttttaa aagttataat gataattatg gtcatctagc aggagataaa
     8521 gttatagtta aggtaactga tattataaga agtgtattta tagatattac cgaacacata
     8581 atcagatatg ggggagaaga aattttaata ttagtagatt ctatagaatc aatcggtgtt
     8641 gaagagattg ataatataga attatatatt aaaagagttt tcaaacttct tgaatttgag
     8701 ggtattgaac atatatattc taaaataaaa aactatataa ctataagtgc tggagtaagt
     8761 ataaaaagat gtcgtagtag aaaagatgtt gaaatattaa ttgaagatgc agataagaac
     8821 ctatataaat caaaaaaagc aggtagaaat caatacatta taatttaaaa ttgaggtgat
     8881 tttgttgcga aaaaaaatag gaattatagc ctctgatatt gaattaaaag aaagaataga
     8941 agaattatat agagaagatg tagaaaatgg aactataata atcgacatac ttaacctaga
     9001 cttaatggaa aatcaaggtc gtatacttgt tgaaaaaggt gcccaagcta taattggtag
     9061 aggtggaggt tatagtttag taatagatac agtaaatgta cctgttatac caatgaatat
     9121 gaagtcaact gaccttttaa gagcaataga aatagcaaag aaatattcta aaaaagtagt
     9181 attgattctt ggagacaatg aagtttcttt tgactatgtt ggctggagaa atgtcataag
     9241 tactgaaata actgaagaat ggtttgaatc taagtatgag ataagaagta aagttgtaaa
     9301 atatatagac caaaaagatg aaattgtaat cgtaggagga ggtttggcat gttcttttgc
     9361 aaggcaatat ggaattgata gtgtatttgc aactgctagt gatgaatcta taagagaagc
     9421 tgtagaatat tgtaaaaaat tattagatac attaggtgaa gaaaagttta ataatgaagt
     9481 gttacgaaat atacttgatg gtataaaaga tggagtaatt gctatagata gtaatggcag
     9541 tataattttg tacaatgaaa gtgcaaaaaa catgcttaaa gtagagagaa aatgtgcact
     9601 taataaatac atcttagatg tatttcctaa aatggagtgg atgttagatt gtttacatga
     9661 aaaagaggac gtagaagata gaaagataag aaatataaat aatctaattg ttaatactag
     9721 gacaacattg ataaaagttg ataatagtac ttatggagtt ttaggaataa tacaagatat
     9781 aaccaagcta caaaacttag aaagaaaaat aagatttgac ttgaatcaaa aaggtctcta
     9841 tgctagatat acttttgatg attttttatt taaagataaa ttaactaaag aatttattga
     9901 agaagctaaa aaaattggaa aaagtgatta tacaacttta ctttatgggg aaagtgggtc
     9961 tggtaaagaa attatagctc atagtataca caatataagt aaaagaaaag ataggccttt
    10021 tgttgctata aattgtgcta ctatagcaga aaatttactt gaaagtgaac tttttggcta
    10081 tgaagaaggt gcatttactg gtgctagaaa gggtggaaaa agagggctat ttgaacttgc
    10141 tcatggaggg actctttttt tagatgaaat aaatagtcta tcctttaata ttcagacaaa
    10201 actattaaga gtaatagagg aacgtcaaat aatgagaatt ggttctgatt atataatacc
    10261 tctggatata aggattatag cagcaacgaa cgaatcttta accgaaaaaa tagttatggg
    10321 tacatttaga gcagacttat tttatagatt gagtagttta gagataaata tacctccttt
    10381 aagagacaga agagaagata taataccttt gtttaacaat tttgtaaatg aagtattaaa
    10441 ggatgatggt ctcaatggaa taaacagtat agatgaaaat tttgttttga ctaaagatga
    10501 aatggataag ctatataatt atagctggcc tggaaatgta agagagttaa agacaatagc
    10561 tcaaaaatat gttgtgacag gtaaaattaa attgagacaa gatagagatt ttaaaactaa
    10621 aaaattactt cctaactctg aagtagacaa atttaattct gaaacgacag caagtgtaga
    10681 agtccaagat gaatctataa atataagtaa gataaatgat ggtaagataa gtatagatat
    10741 aaaagaagta aataagtatg ttgaagaaaa aataataagt atgctttttg ctcaaggact
    10801 ttctaaaaat gaagttgcac aagttcttgg aataagcagg acatctttat ggaagaaata
    10861 caataaaaat atttaaatat aattacatat aaattatttt gaagtaatgt taatttttta
    10921 aaacaagtgt taagaaaaat taacattact tttttgcaaa tttttatttt tttagacagg
    10981 catatatatt tataagaaaa atagttaaaa cacttaattt aataatgaaa aaaataataa
    11041 ttctaaacaa aatcaatttt acataaagtg ggatttattg gcatagtaat tgcttaatat
    11101 ataatgtaag agtaaataca attttagggg tgatggtatg agtcaaagta tggttggtaa
    11161 gcatgcaatg tggccaaaag aaaatgatgt tatatttagc atatctggca gagctcaagc
    11221 agcagagaag gcttttggta tggataatgt aataaatgca acaataggcg ctctaatgga
    11281 tgattcagga aaattgataa caatgaaaac tgtatatgaa gaatataaag cattagataa
    11341 ctgtgagata ggtgcatatg cagctcttga aggtcaacca gattacttag aagcagttaa
    11401 aaaagtattt ttcagagatt acttaccaga aggacatata agagtattag cttcaccagg
    11461 aggaagtggt gcaataaaat tagctgtatg gaactatact aatgaaggag atgaggtatt
    11521 aacatctgat tggttctgga gtccatatgt aagtatagct gaagaggcta atagaaaagt
    11581 agttaattac caactttttg atgaaaatag aaggtttaat tttgagtcgt ttaaagaaaa
    11641 atttgtaaat atagcagaaa aacaaggtag agtctttaca attataaaca caccagcgca
    11701 taatccaact ggatatagtg ttgcagatga tgagtgggat aaaatattag acttatcaaa
    11761 agaagtcgca aaagataaag acaaaaagat aatatttttc gtagattcag catatattga
    11821 ctttgcaggt gatgatgatg tatgtagaaa gttttttaag aaattttcta atttgcctga
    11881 aaacgttctc gtattggttg gattcagtat gtcaaaagga tttacagctt atggtatgag
    11941 aatgggggct ataatttgta tatcttcaag tgaagatgta gctgaagagt tccattactc
    12001 atgtgttcat tcatgtagag caaattggtc aaattgtaat agaagtgcca tggcagtatt
    12061 atctaacatt gtaaatgacc ctaaaaaatt caaagaatat gaggatgaaa aagaaatata
    12121 caaaaacatg cttactagaa gagcagatgt atttgtaaaa gaagctgaaa gagtaggatt
    12181 agaaattctt ccatatatag caggtttctt tgtaagtata ccatgtgata atccaaaaga
    12241 agtatgtgaa gaattgacta aacataattt atttgcagtt ccattaaaaa tgggtttaag
    12301 atttgcagtt tgtgcagttt ctgaagataa atgtaagaaa gcaccaagta ttataaaaga
    12361 agcacttgaa agtttagaag taaaaataaa taattaattt cattgaacaa attgggtgga
    12421 ctatgaattt aataattgta gatggaggga attttatatg aaacaattga tgacaggtaa
    12481 tgaagcaatt gcacgtggag cctatgaggc tggtgttaaa tatgcatctg catatccagg
    12541 gactccaagt acagaaatat tagaaaatat agcaacatat aaagatgcaa tagttgcaga
    12601 gtgggctcca aacgaaaagg tagcacttga ggctgctata gggggttcaa ttgcaggagc
    12661 aagaacaatg gcttctatga aacatgttgg tttgaatgtt gcagctgatc caatatttac
    12721 ttatgcatat acaggggtaa atggtggtat ggtacttatt acagcagatg agccgggaat
    12781 gcattcatct caaaatgagc aagacaatag gatgtatgca aaatttgcaa agataccttt
    12841 atttgagcca tcaactagtc aagaagctaa agatatgata aaagaagctt ttgaagttag
    12901 tgaaaaatac gatacaccag ttttatatag agttacaaca agactttgtc attcaaaagg
    12961 attagtggag tgctatgata gagaagaagt tgaaattaaa gagtatgtta aaaatgctaa
    13021 gaaaatggta actgttccag caaatgctca aataagaagg ggcgttgttg aagaaagaat
    13081 ggaaattctt aaaaaattct caaatgaaac tgatttaaac tactatgaaa taaatgatac
    13141 aaaaataggt gttatagcct ctggtatgtg ctgtaatttt gccaaagaag tttttggaaa
    13201 aaatgcatca tatatgaaac taggatttac aaatccatta ccttatgaaa aaataaaaga
    13261 atttgcagaa aaagttgata aaatatatgt tatagaagaa aatgacccat ttatagaaga
    13321 acaaataaaa gcatatggaa tagattgtat tggaaaagat gtaataccac catatggaga
    13381 aatgacacca gatgttttaa gaaaagctat atttggaaaa acaaatgata ctatagaata
    13441 caaatctgaa ttagtaacac caagaccacc aagtttctgt gcaggatgtc cacatagagg
    13501 attcttctat gaacttggaa agagaaaaaa tttaatagtt ggtggagata taggttgtta
    13561 tactcttgga tttgctcctc catataatgg aatagattat gttgtttgta tgggttctgc
    13621 ttttggaact gcacatggag ctcaaaaagt tcttaatatg aaggatgata atgaaaaaag
    13681 attggtaggt gtacttggag actcaacatt cttccataca ggaataaatg gacttttaga
    13741 tgttgtttac aatagaggta attctatttc ggttatatta gataatagaa taactggaat
    13801 gacaggtcac caagaaaacc caggttcagg atatacttta caaggtgcta aaactaaaga
    13861 agttgatata gaaggattag ttaaagcttg tggaatagaa catgtaagag ttataaaccc
    13921 taataattta aaagaagtaa atgaagcact agattgggct ttagctatag aagatgaacc
    13981 atcagtaata ataacaagat ggccatgtgt acttaaaaaa ttctctaaag aagatataga
    14041 agaatttaat aatccattta agactaagtg taaagttgac catgataaat gtataggatg
    14101 taaattatgt ttgaaaactg gatgtccagc tctatcattt gataaagaga ataagttatc
    14161 aaatatagat agaaatcagt gtgtaggatg tggagtatgt gcacaagttt gtccaaaaca
    14221 agcaatagtt aaggaggaaa aataatatga ctaagagtat acttttggta ggtgtaggag
    14281 gtcaaggaac tatacttgct agtaaattat taactatggg attgatggaa gctggatatg
    14341 atgtaaagat gagtgaaata catggaatga gtcaaagagg aggttcagtt tcctcacaag
    14401 ttagatatgg agattgtgtt cattctccag ttatagaaat tggtggagca gatatattag
    14461 tatcttttga aaaaatggaa gctttaagat ggttcaatta tttaaaacca gaaggaaaag
    14521 ctttagtaaa taatcatagg atagattcta tgactgtttt aatcggagga gctgaatatc
    14581 aagaaagtga tatagatgca gagttaagta gattaaatgc aaaagttata aatgcagctg
    14641 ataaagctga agaactagga aattcaaaaa taatgaatgt tattttatta ggatgtctag
    14701 ttaaatctat gcaattagag tctattgatt gggaaaaaat tataagtgaa aatgttaaac
    14761 caaaatttgt tgaattaaac ataaaagctt tccatgaagg tatggaaatg gttagcaaat
    14821 agtttataat agatataaat agactataga aattaaggtg aaaggaagaa aattatgact
    14881 tacagaatat tagccataaa tccaggttct acttctacaa aaatagcagt atatgatgga
    14941 gaagaacaaa ttcttgtgaa gacgatagac catccagctg aagagattgc aaaatataat
    15001 actatacaag accagtttga aatgcgtaag gaagcagttt tgaatattct taaagaaaat
    15061 agtatagact taaaatctct tagtgcaata gtaggaagag gtggagtttt accaccagta
    15121 aaatcaggag catatttagt aaatgaagaa atgattgatg tactaagaca tagaccagta
    15181 cttgaacacg cttccaattt aggtgctgtt gtggcacatg caatatcaga acctcttgga
    15241 atcaactcat atatttatga ttctgttgca gtagatgagc ttatagatgt agcgagaata
    15301 tctggacttt gtggaatgga tagatcaagt gcagggcatg cattaaatac tagagcaatg
    15361 gctttaaaat atgctaagga taaaggaaaa gattataaga gcttaaactt aatagtagct
    15421 cacattggtg gaggagtaag tatttatctt catgaaaaag gaagaatggt tgatatgcta
    15481 tctgatgatg aaggaccatt ttctccagaa aggtcaggaa gagtacctgc tacaaaatta
    15541 gtggctgcct gttattcagg tcaatattca gaaagagaaa tgactaaaaa gataagaggt
    15601 aaaggtggta tagtttcata cctaaatact gtagatgcta gagaagttga aaaaatgata
    15661 gcagaaggaa atgaagaagc aaaaattatt tatgaagcaa tggcttatca gttagcaaaa
    15721 ggtattggag agttagcaac tgtagtagat ggaaaggtag atgctataat tataacaggt
    15781 ggaattgcat attctgaaat gtttacttca atggttaaaa agaaagttga gtttatagca
    15841 ccagtagaaa ttatggcagg agaaaatgag ttggaatcac ttgcttttgg aactttaaga
    15901 gtactaaatg gagaagaaga agctagaatt tatagtgaaa attaataaga aaaactaaaa
    15961 atgtttatat actaaaaaag tggtatatcc gttttttata cacgaaagct tagagtatag
    16021 gtgaaaatgt ataaaatttg gattgccact ttttataatt aaaattttat cttaacctaa
    16081 taaataattc tgtaaaattt cgtatttata tatatatttt attggtattt attgttatta
    16141 ttattatgag gagtgatttt tgatgggaaa aataagttta aaaagtatga taagattatt
    16201 ttcaggtttt tttatatttg caatttcttc tgtgcttatg attaatgcac atgtaggtct
    16261 tatgccttgg gatgtacttc accaaggttt atctataaag ctaggcataa ctataggtca
    16321 ggcttctata atggtaggag ttgtaattgt tatattggat gcagtttttg gtgaaaatat
    16381 aggatggggt actttactca acatgacatt tataggaatt tttattgatt tagtaatatt
    16441 ttctggagtg atacctcatg caagcaacac ttatataggt gtgtttatgg ttgttatagg
    16501 aattattttg gcagctatag caagttttct atacttaggt gtttgtttag gaagtggacc
    16561 gagagatggg cttatgattg ctcttcagaa aaaaactaat aaatctgtac gtcttgttag
    16621 aacaattctt gaaatactag cattagttgt tggatggtta ttaggaggtt ctgtaggtat
    16681 tggtacgctt gtaagtgctt taggtttagg atatgtatta caaatagtgt ttagaatatt
    16741 taaatttgac acaaaattgc tgaaacatag atttattata gatgatataa gagaatggaa
    16801 ggaaaagaaa agcaatgaac ataaatgtaa atcaagtatt gtaataaaaa atgagcagaa
    16861 ttaattatgc taaaatatat ttgtagttta tctaatttat agtaaagtca aggagatttt
    16921 gaaatggaat tatgggattt atataatgct gatggaatta aaacaggaaa tgttataaaa
    16981 agaggtaatt ctattgaaga aggttattac catttggcag ttgaagtgtg gattttaaat
    17041 agtaactctc aaattttaat tcagaaaagg tctaaaagta aaaaaacatt gccaaatatg
    17101 tggggaatga caactggatg tattgtttct ggggaagaca gtttagaagg agcaattcgc
    17161 gaagcaaagg aagaaatagg gatagatata actaaagatg agatgaaagt ttttagaagt
    17221 atgattcatg aagatactct ttgggatgta tacttagtta aaaaagaata tgatatatct
    17281 aaagctattt tacaggagga agaagtaagt gatataaagt gggtaagcac agatgaaata
    17341 agacaattac taaaagaggg tttgtttttt gaatatccag agatatacga attgctatat
    17401 gagatagata ataataaatt aaatatatga tgtagagcag atttcagtat aagtaagatt
    17461 atttaaaatg tatcttctct aaattttaat attgttttat gaaaattaat aagttatttt
    17521 tagtattttt ctacttgttt tttgagatta aaataaaaag ggcagtcatt ataaagtcat
    17581 aaaaatttgg ggaggattta aactatggaa gataacaaag gattggcacg tgacagttca
    17641 aaatataaaa ttgtttctat atctgtcgta gtaattattc taattacatt ttggtatatg
    17701 ttaaatatgg tgcttttaac atttattatg acttttattt tctataactt gcttgtagcc
    17761 acaagaaaac gaattaagaa gttttcttct ttaaatattc cagattcatt gataattata
    17821 gtgttatatg cactatttgc tatattgtta gtattgatta gctatgcagt tgtaccaata
    17881 attatagttc aacttacaga gttgagtagg gtttttagtg attttgatgt aaatcaattt
    17941 gctcaatctt taggaccgaa attgtatcct attgtctcaa agctggattt taataaatat
    18001 atttcacaag cagggctact tatagcatca acagcaacaa aagttggaag ttttggagta
    18061 aatatattat tggcattttt actgagttta ctccttttac ttgaaaaaaa tgaaattaaa
    18121 aattttggag ataaactttc tgatagtaag atttctttta tttataattc gcttgtattt
    18181 tttggaaaga gctttgttaa aaattttggt gaagtaatga aagtacaagt tatgattgcc
    18241 tttataaatt ctgttgtttc tatgattttc ttaggtttca tgggattccc tcaaatatgg
    18301 gctttaggat ttatgatttt tgtgttgggt cttattccag tagcaggagt tatagtgtct
    18361 ttgattccat taactgtaat agcatttaat acaggaggaa taacaaaggt ttttggagtt
    18421 ttacttatga tttgtatagt gcatgcagta gaaacataca tattaaaccc taagttgatg
    18481 tcgaatagaa ctaaacttcc agtttgtttt gtttttatta ttttacttgt aggagagcat
    18541 tatttaggtg tatggggatt actaattgga gttccaatat ttatgttcct tatggatatt
    18601 ctgggtgtta aatttacttc taggtaatat attaaaataa taatttattt ttatatataa
    18661 attatgaatt gttttaaaaa agaacctata aatagacatc attaataaag acatctattt
    18721 gataggttca attttgcttt gtataaatac tataaaacta aataaaaaga aatttatttc
    18781 atttcaaaag tttcacaact tgcatttctt tcatttatat gaactttttc agctttgcaa
    18841 agttcatttt tattgtattt acattttaca gcttcacaat gaatgttatc tgtatcaact
    18901 tggttagttt cattagaacg actagttata ccagatgtat atttgtcttc aaaagaagca
    18961 caataagtat tttctgtagt agttgcttgc attccatcta cttttatact accagcataa
    19021 caatatccac tagtattata agcacaatta gtagcagcac aatttaaatt attatttttc
    19081 ataaataacc tcctaagttt tatttaaact tattatgtga agttatctaa attttataca
    19141 cttatttaca attacattta tcacatttaa caactacatc tttggaagtt tcccttccta
    19201 aatttttatt aacatgatac acatcaacat tttcagttga tccacatata gaacatttaa
    19261 aattgttttc tagtagggtt ctttctttaa ataacttcca atacatagaa ttgatgtaat
    19321 cattataatt taccttgagg catgtctcaa gaaagtttat gtatagattg tctaaatctc
    19381 ctgtatttaa ttctgtatat tctggttcaa aatattcaca acatcctcta aaatcgggct
    19441 ttgtatctga aataacacat ctaatatcat atctatagtc taggctaggc cccttaaatg
    19501 aaagatgtgt gcaaaaagaa caagatattt ctggtagatt tttttcaagt tcatgtaatt
    19561 tattattcat aagtattcct ccaaaaaatt tattttaagt atataaatga atagattatt
    19621 ttaaaacttt tatttattta tattagagat ttaggataaa tattccaata aggagtaaat
    19681 acttaagtat ttattactgt attaaataaa aaagaggcaa atctaacttg agattgccta
    19741 cttttttatc attttttaat aaaatttatt ctaagtatta ttttatttag atttagtcag
    19801 ccaacttagt atctgctttg ctttttaact ttctaccaga gcgtacagtt aaaatagcat
    19861 ataatacagt aaatatggca gctaaaacat atgatatatt tatgtttaag ttaaatccaa
    19921 tttgagcatt aaatatataa ctgaatataa caaaggaata aaacatacca ggaattaagc
    19981 ttataatata attcttttct tttattataa ggtaaactgt aatcattgca aatgcaaata
    20041 tggcaatagt ttgattactc caagagaagt atctccacaa tatattaaat ccagaagcac
    20101 taagctttgc aaatataagg atggctatga caggaataaa tatacagatt gacaatataa
    20161 cacgatgttt cttttccttt tggtcataat gaaagtaatc tgcaagcatt aatcttaaag
    20221 atcttaaagc tgtatctcca gaagttattg gtaaaacaat tacacctatt atagctatga
    20281 taccaccaat agaaccaagt aaatctcttg caaccaaacc tattacatca ggagaaccta
    20341 ctaattcttt aggtattcct ttattgtaaa tacccatagc agctgcagcc caaatcattg
    20401 caattaaacc ttctaaaatc atcatattat aaaaagtagt ttttccttct ttttcatttg
    20461 aaactgatct tgctataaga gtagcttgag ttgagtggaa tccagaaaca ataccacaag
    20521 caactgtaac aaagaatgta ggaataagag gaataccatc aggatgaata cctttccaat
    20581 ttgcaagact taaattagct aaatcataac cttgtgtaaa gattccaatt ccaacaccag
    20641 cagcagataa aagtagaata gctccaaata ttggatatac ctttcctatg attttatcaa
    20701 ttggaaatag tgttgcacac aagtaatata gaaagataag tccataaact atccagacaa
    20761 ctggattatt tatagtcgat ttcatattta aaatttgagt aacaactaaa tccccaggtg
    20821 tataaataaa aactgcacca actaaaagca ttaaaagaca aaggaatata ttatagactt
    20881 gaaatacttt attacctaaa aatctactga taagagaagg catttgtgct cctttttctc
    20941 ttatactaat cattccactc atatagtcat gcaaagctcc tccaaataca cagccgatag
    21001 gtattagtat gaatgctatt ggaccaaaca atataccttg gataggtcct agaattggtc
    21061 ctgtaccagc tatattaagc aactcaatta gactattttt ccattttttc attgggacat
    21121 agtctactcc atcactttga gcaagtgcag gtgtttttct gtcatctggg ccaaatactt
    21181 tttcacaata agcaccatat aaagcacctc ctattagtaa tatagccaag ccgattaaga
    21241 atgttgtcat aatatcaccc catttataaa attttttggt ctttgtatac atattatcta
    21301 aatgtgtaga tttatattga atttaattct ggacaaccta caaattctat aaagtattac
    21361 aactaatata atttcagaaa taaatacata tacataacca tgtacttagt atacaggtat
    21421 ttggtaatat tttcaatgtt atagcaataa agaatataaa caaaattctg ataatatttt
    21481 acaaaaaaat taaaaaatat aaaaattagt ttaaatagat ggagaaaaaa ggaaaatcaa
    21541 ttgagaatat aaatgtctat atcttaacaa tattaagagg tttaaaattc ttgaagaaag
    21601 aatagtcaag tgatataatg ggtttacagg tgtatataca ctagtacata tagaaagcgg
    21661 tgcaattatg gataaagatt taacatatca aatcaaagag ctaaagaaag aaaaaaatgc
    21721 aataatactt gcccattttt atcaaccacc agaaatacaa gaattagcag atgcagttgg
    21781 tgactcatat tatttaagtg agattgctag agattgtaaa gaagaagtgg ttgtattttg
    21841 tggagtaagg tttatgggag aaagtgctaa gatattatca cctgaaaaaa ctgtattgat
    21901 gccagtaagt aacgctgggt gtgctatggc agatatggta gatgaagaag gcgtgataaa
    21961 attaaagcaa cagtatccaa atgctttggt tgtatgttat ataaactcta cagctaaagt
    22021 taaggcacat tgtgatgttt ctgttacatc ttctagtgca attaaaatac tagaaaacat
    22081 agataataaa gaaattatat tccttccaga taaaaattta ggaggatata ttgcagaaca
    22141 atttccagat aaaaacttta tattttggga cggatattgt aaataccata acaatataag
    22201 agctgaagaa ataattgagt taaaagataa gtataaaaat gcagaagtat tagtacatcc
    22261 agaatgtaaa aaagaaataa gagatttagg agattatgta ggtagtacat caggaataat
    22321 aaaatatgct actaatagta aaaacaaaga ctttataata gcaactgaag aaggtatatt
    22381 acatgaatta aagaaaaata atcctaataa aaacttttat attcctggtg gaaaaatact
    22441 atgtacagat atgaaaaaga caacattaga aaatttatat agtacactta aaaatatgga
    22501 aaatgaagtt attgtagaag atgaaatcat ggaaaaggct ttaaattcac tgcttaacat
    22561 gcacaaatta gcagaaggat agagggatag acttatgaat ttagaacaag atgttttaat
    22621 agttggaagt ggagtttcag gattatactg tgcattaaat ttagataaaa gtttaaatgt
    22681 gctagtagta tcgaaatcaa caattgaaaa caacaataca tatcttgcac aaggtggaat
    22741 ttcaactgct agaaatattg atgatataga atcctttgta gaagatacaa tgaaggctgg
    22801 gcagtataaa aatagagttg aagcagttca agtacttgca gatgaatcta tagaaaatgt
    22861 aggtcagata gtagaatatg gtatgccttt agacaaagaa aatggagaga tagattacac
    22921 aagagaagga gcacatagtg taaatcgaat agttcatagt aaggataata ctggagaagt
    22981 tgtttttaaa actttattaa aagaagctaa aactagagaa aatataactc ttatagaaga
    23041 tgcatatctt ttagatatat taaaagatgg caataaatgt ataggagcta gaatttttaa
    23101 atctaaaaaa gagattcatg ttttttcaaa aatagtagtt ttagctacag gtggaattgg
    23161 tgggcttttt aaaaattcta ctaatcaaag acatcttaca ggtgatggaa ttgcaatagc
    23221 tttaagaaat aatataaaaa tagaaaattt agaatatatt caaatacatc ctacagcctt
    23281 ttatgaagaa aataatgaag gtaggagaat gcttatatct gaatcattaa gaggagaggg
    23341 agctaaactt ttaaataaaa ataaagaaag atttgtggat gaacttcttc ctagagatgt
    23401 agtttcaaaa gctatttttg agcaaatgga aaaagataaa ttaccttatg tgtatttaga
    23461 tgcaacacat ttagatagtg aatatttaat taatagattt tcttttattt ataatgaatg
    23521 tttagctaga ggaacagaca taacgaaaga atgtataaag gtatctcctg cacaacatta
    23581 ttttatgggc gggatacatg tagatttgga ttcaaaaaca tctatggaaa atttatatgc
    23641 agttggtgaa attagttgta caggtgttca tggagccaat agattggcaa gtaattcatt
    23701 acttgaaggg cttgtatttt caaaaagagc agctaaaaat ataaactcag ttatagataa
    23761 tgtaaaagtt aagtttatag atgtaccaga tatggatata gatatagaac aggtaaaaaa
    23821 agaaaataaa atattagtca taaaagaaat tgaaagaaca agtgaggatt ttggcgatga
    23881 attatttgat tattgataga atgatacagg atgctttgat agaagatgtt ccaagtgaag
    23941 atataacaac taattctatt gtggatgaaa attctaaatc tactgtagat ttaatttgca
    24001 aacaagatgg tataatagct ggcttaggtg tatttaagag agtttttgag atacttggtg
    24061 atgtagatgt aaaattatat aaaaatgatg gtgatagagt aaagaatcgt gaaaagatag
    24121 ctgtattaac aggtagtact agaaacttac ttgtaggaga gcgtgtagca ttgaattatt
    24181 tacagagaat gagtggtata gctactatta caagtaggta tgttgaaaag cttgaaggta
    24241 caaatacaaa attattagat agtagaaaaa cgatacctaa tcttagaata ttagataagt
    24301 attctgtcaa agtaggtgga ggatgcaatc atagatttaa tttatctgat ggaatattgc
    24361 ttaaagacaa ccatattggg gctgctggta gtgttaagaa ggcagttgaa ttagctagaa
    24421 aaaatacttc ttttgttaga aagatagaag tggaagtgga aactttagac atggtaaaag
    24481 aagcaataga agccaatgca gatataataa tgttggataa tatgagtttg gaaatggcaa
    24541 aacaagcagt agatattata aatggaagag ccattgtaga attttccgga aatgtaaatt
    24601 tagatactat agaagatata ggaaaaattg gtgtggatgt tgtttctgta ggagcgctta
    24661 cacattctgt taaagctctc gatataagta tgaagaattt gagaaatata taaattttat
    24721 attgaaataa acttaattaa aatagactcc ttaaatttgt tttataaatt taaggagtct
    24781 attttttatt cattaaaatt aataaaaata gaaaaaaatc aatcaataat ttaataaaaa
    24841 tagataaata ctatatacac ttttaataat atagttaata tctattttac agataaataa
    24901 gaataaactt ataatataat tgtatctgta aaattttgta aaatataaaa agtatagggg
    24961 gaataaaaat gaaagtagct tatattttta gtagtactaa tacacataaa attctagaca
    25021 aaatgataat accacaactt gaacaaggaa ctcatggagt agacgttcta gggatgtttt
    25081 tctttatgga taatacctta tttttatcta aaggtaatcc tgtaggcgag agactaagta
    25141 aattacatga aaaaactgat atgataataa tggcttgtga ccaatgtgct atagaaagag
    25201 gtatagagaa taatttggtt gatggagcta caattggatg tttcccaaac ctatatgctt
    25261 gtttaggcag tgcaggtgtg gaccaagtta taacgttata aattagtata ggatacaatc
    25321 catagaaaaa tttattttct gtggattatt ttaagtaaaa gataaattgt ttaaagtagg
    25381 ggatgaacaa atgtctaaaa ttttagttga atttataaac acttgaccat cttgtgatga
    25441 acatggagtg tttataaaaa aaatgtcaga aaagtatgct gataaattgg aaataaaatt
    25501 atatcaagca gggaaagatt tttcgtatat aaaaaaatat gggattataa caaaaggaac
    25561 tttaataata aatcagaaaa agaaatatga tagattaaat aaagatacaa ttgaaagggc
    25621 aatagtagaa gctataaaca ataattaaaa gtttaaaaat taggagtatc aaaaatgaat
    25681 atattagaaa ttgttttaaa tggagttaaa gatactatag tagcttctat agttacactg
    25741 aatggagcat caggatggct tatgataagt tttatcttgg caggtgtact tcacaatgtt
    25801 ttaactccaa gaaggtttca aaaacaactt ggaaataaga aattttcttc tttaattaaa
    25861 agtactatct caggaatgtt tttaccaata tgtagttgtg gagtaatacc acttggaata
    25921 agtatgtatt attcaggagc atatttagga ccagtacttg cttttatgac atcaactcca
    25981 ataataaatc caatagctgt agttctttgt ctaggtcttt taggtcctaa agttacaatc
    26041 atttatctaa tagctggttt tttagtacca tttttagtag gatttttagg aaattgtttt
    26101 ggaaaagaag aattatcact tcataatgat tcagaggaag aagtaataga attagaagaa
    26161 gaaaaaagaa gttttatgga aaatatgatt gatggtctta aatggtcttt tggtgaatta
    26221 gcccttacta ttagtaaata tgtagtaatg ggtatggttt ttgcaggatt tataacaact
    26281 atttttccaa atagtataat tcaaaaatat ttaggaaatc caggtttgct atctcttgga
    26341 agtatagcaa tacttgcatg tgttatgtat gtatgtgctg taggacatat accgtttata
    26401 gcagcccttg ttgcaagtgg agcatctcct ggtatagcga taacatttct aatagctgga
    26461 gcagctacaa atctaccaga acttataagt atgtttaaac ttattggaaa aagaactgtt
    26521 attatatatt ctgtaacttt gacactgtct tcaataataa ttggatatat aacaaattta
    26581 cttttagtga ataataactc agtaaattta gatgcaacaa attcttcaat acagttggca
    26641 aataaactaa tgttaaatat acctgatagt tttgagtatg tatgtactat tttaattatt
    26701 ttatttgcat ttaaatcaat aataccaaag atgaaagagg tcataggaaa tcatgcttaa
    26761 aaagatagtt ataatatcct gcatagtagt tgtgttaatc attttatcaa aaatagttga
    26821 tgataacatc aaagaagatg cttctattcc aaatgtgaat aaagaaacat tagaatattt
    26881 tagaaaaaat tataaagaag acataataac ttgtgctgaa gaagacttaa ataatgatgg
    26941 gaaaaaagat ttagtagtta tatataaaaa aagcaataat tcaaatgaaa tggtagtcgt
    27001 agtttctgat aaaaatagcc actatataac aaagccaata ccagcaccta tagagaatca
    27061 aactataacc tttaaaaata ttgatgataa agcaccaata gaagtaattg tatcagggtc
    27121 taaaaatggt aatgtaggat atgctattta cagagtagag ggtaaaaaat ttgttgattt
    27181 atttggcgaa gatatggaca aatgttgcta aaaataaaaa taatacataa aggtgggaaa
    27241 tttatatgaa attatctaag aagattcaag cattaatctt atttggtgta atgggtacat
    27301 ctatattaac aggatgtagt agtaaaccaa aagaaaaaga agaagcaaaa actggaaaag
    27361 atgattatac aataacagta ggttattata attgtgacca tatgactgcg ggaccagtag
    27421 cagaatcggc aggaatatat aaagatttag gtcttaatgt aaaaactgtt ggaaatggta
    27481 aagttcctga agctatggca gcaggaaaaa tggatgcagg ttacatagga actaaggggt
    27541 tagttggagc aatacctaag ggttcaccaa taacaatagc agctaacaac catactggtg
    27601 gttctgaata tttaatagtt tcaaaagata taaaagaacc taaagattta ataggtaaaa
    27661 aaattgcaac agatatgagt gatttcttat ggacaagtga ttatggtcca gaaacaggtc
    27721 taccaactga cccatcaaaa tatgaagttg taaatatgga ttcagacaaa gataaatatt
    27781 tagctcttaa aactgggaaa attcaagctt ttacatcttg tgacccttgg ggttctgtag
    27841 ctgaaaatga cggtgcagga aaaataatag catctactca atataaagaa aaagctaatg
    27901 gcaaagaata taactgttgt tcattctcat taaacaaaaa ctttataaaa gaacatccag
    27961 atttagcaaa aaaattggtt ctagcacata caaaagcaat agaatatata tatacaaatc
    28021 cagctgaagc agctaaaata tttgcaaaat attataatgt agaagaagaa gttgcactta
    28081 gaactatcta taagaagact gttggagaag gtagaactct tacttggaaa gttacaggtg
    28141 aagaatataa aaataattta caaatgtata aagatttaaa ggctttagat gatataccta
    28201 aatatgaaga tacgattgat acaagcttat tggactcttg tggagctgat gattttgaca
    28261 aatttataaa agaaaaagtt aacccagagt ttcctgaagg tatgagttat gaagactgga
    28321 aagcaaaggt attataaata aatggagaat atgaaaaata taataatact ttttatcatt
    28381 attttgggaa gtatatttat aatatttttt aattttgaag ataaagaaga aataaaagga
    28441 aaattaagaa taggggtatc tgatgatacc tctggttttg taataaatta tatggtaaat
    28501 agagactact ttgaaaatat aaaagtaagt gatataatgg atatttttac aattaatgat
    28561 tgctgagcaa gtacaatgca gtgggctctg agttcagagg aaatagatat agcaatcata
    28621 tgtaaagatg ctgcaaaaca atatgtaaat gtaaatagtg gatttgaaat tgttggtact
    28681 gtagttcaaa attctgatat atttctatta agtgataata atcctgaaaa gataggagtc
    28741 attcaaaata gagattacca gtcagaattg gttaaaaaat actacaagaa tgtggaagta
    28801 gctcccttat tagggactgc actagcatat ggattagaaa gtaatttagt agatggtgtt
    28861 gtaatagatt gcataaagtc aattgggtta gagggcaaaa gaaaatctac aactaaatta
    28921 ggagattatg atacctatgt attagttgta agtaaagagt ttaaaaaaag taaagcatat
    28981 agtgatttta taacacttta caataaaagt gttgatgctt taaagaataa agctacattt
    29041 aagaaagcat taaaagagta caggaatata agaaatatag atatggagga aataagcaat
    29101 tggaaattaa aatttctaaa gataaaagcg atagattaac taagaaaaaa actgatggta
    29161 gtatggatat tttatataaa ataatactat tagttattat atttttagtc tggcattttg
    29221 cagcaaaaga tatagggagt tctttgttac ttccaatgcc agtagatgta ataaaaggtt
    29281 tctttttctg tgtgacagat gcagagacag tcactaatct ttttataaca ttgcagagag
    29341 tacttaaagg ttttatgtat gcattattgt ttgggcttcc aataggattt attatgggat
    29401 tttctaaaac ttttgaaagg gttttatctc cagtagtaga ttctgtaagg caagttccaa
    29461 taatggcatg ggttcctctt actatagtat ggtttggtat aggagatggt ccaacaatat
    29521 ttttaatagc tttttcaggg gttttcccta taattttaaa tactattcaa ggagtaagag
    29581 caatatcaaa ggattattat aatgcagcta gaagtatggg agcatcgcca attgtgatat
    29641 ttacaaatgt aattgttccc gcatctcttc cagatatact aactggttca aggattgcta
    29701 taagtacagg atggatgtct gttatctgag ccgagtttat agctacgagt gccggtctcg
    29761 gttactcaat ggtacaagct caaacattaa tgcatacaga tgtattaatt gggcttatga
    29821 tatttgcagc tttaatagga tttataatag atagggtatt aaagtttata aataaaatcc
    29881 tttgtagatg gaggtttgca gattaatgaa gttaagtgta agagatataa ataagacatt
    29941 tgtaaataat agagtacata caaaggtttt agaagatata agtatggata tagatgatgg
    30001 acaatttgtc tgtcttttag gaccatcagg ttgtggaaaa acaactttac ttactataat
    30061 aggtgggttt caaaaatcag aacgtggaga tgtttttata aatgataaaa gagttaaaaa
    30121 accgggcata gatagagctt ttatatttca aaattatgct ttatttcctt ggaaaactat
    30181 aagaggtaat gttctatttc ctatgaaaca gcagaaaata ccaaaagaaa aaagagaaga
    30241 aatgctagaa gaacttttgg ttatgtcaga cttgaaagga aaagaaaaac tgtttccgca
    30301 tcaattatct ggaggaatga aacaaagagt ggccatgata agagctttag catgtaatcc
    30361 agaggtatta ctaatggatg aaccattagg agctgtagat tttcaaatga gacaaaattt
    30421 acaggaagag ctagaacgaa tatggataaa gaagaaaata actgcattaa tggtaactca
    30481 tgatgttgat gaagctgtat atatgagtga tagagttata gtaatgtcga gagataaagg
    30541 aagaattatt gatgatataa atatagatat tccaagacct agaattagag gaagccaaaa
    30601 atatgaagag tacaaaaaca aattaactga tactttatca aagtgttatg aagtttaaag
    30661 aggagtagac atgagtcaaa tagaaaaata caatagtttg gataatacac aacagaaaat
    30721 aagaatctct attatggata tgataataga taaaggttct agtgttacac ttcaagaagt
    30781 gactgaatat ataagtaaaa agttgaatat agaaaaagaa tatatagaaa ggacactaca
    30841 atattttatt tataaaaata taatggttgt tgatgggaat agtataaatt ttatatatcc
    30901 tgtatcagca ttgccaacaa atcataaagt aactttgaga gataatagaa gtttcagtgc
    30961 aatgtgtgct atagatgcta taggaacctc ttgcacattc aaccaagata taaaaataaa
    31021 ctctatttgt agtgctacag gtaaggaaat agaagtaatt ataaaaaatg aaaagattga
    31081 gtatgtgaat aatccaaact taagagtgct tcatataaat cttgataagc atctaaattg
    31141 ggctgctagt tgctgaaata taatgaattt cttctggacg aagagtgatt ttgatgcttg
    31201 gacaaacgaa gcgggattat ctaatgatga agatatatat tgtttagata ttaatgaggc
    31261 aatagtagaa tcatataaaa tatttaaact caaacaaaag gtactatcat agatatacat
    31321 atatgaaaaa ctaaaaatga cctttagata aaaatgatag gtaatatcca tactatataa
    31381 attagtatag agtagggatg tgaaaagtat ttaaatctaa aggtatattt ttagtttttt
    31441 ttagatgatt agatagcctt attaagtata tatttattta taacctttgc aactccattt
    31501 tcattattag tatcagtaac ataatctgca atttccttta tactattacg tgcattcccc
    31561 atagccacac caagacctgc atactttatc atatgttggt cattttcttc atcgccaaca
    31621 gcaatagcat tttctatagg tatatttaga ttcgtacata atgttttaag agcagttcct
    31681 ttattagtag ttttacctaa aaattctaga taaaaaggag cagaccttac tatagtatat
    31741 ttattgaata aatttttagg tagttgctgt atgatttctt ccaatctttc tggttcatca
    31801 actatcataa ttttacagat tttaatagat tcatcaattt tatctttttg tatatatttg
    31861 acttctatat tatttaattt cgcttcatga agtgtatatt tgccaggcgt ttcatttggt
    31921 gtaattaaat ttgtcattgt atttatgtgt attttagtct tatatttttt acaaacgtta
    31981 ttatatataa aatcaaaatc atctaaactc atttctacat catgtatgat tttctcactt
    32041 ttaacttctt gaataattgc tccattaaag catataacat aatcaccttc atctgttaaa
    32101 tttagttgat ttagaagttc ttttacacca ggaagaggtc tgcctgttgt tataactact
    32161 tttgccccag ccctttttgc ctcctgaatg gactcaaaga cttcaggagt aatccttttt
    32221 tgtgtattta atattgttcc atcaatgtct agtgcgatta atttgtacat atcaacctcc
    32281 aataaattat atactcaaat ttcctgtgaa aacgttgaca cagctagtgt tgaacaaagt
    32341 ttcagtggga aatatggttt gttttgtata ctattatatc aagagataag taatttagaa
    32401 agtttaataa tattaatttt ttgataaaaa tattacttat gtgagatgag aatgtaaaaa
    32461 ctttgtaatc aataattcca aaattcttaa ttacaaataa tggtatcgtt tgcattgtta
    32521 atataaataa atgtatatta tatagttaga agtttgaata aatagactga tggtaatttg
    32581 ttatattagt tagttttgtg ttataaaata ttgtaattcc attaatcata tgttattatt
    32641 caacatgatt ataatataaa gaatatttga tatatataat aatttataaa agagtattac
    32701 atagtacatg taaatctata tttataaata caataaagta aagttgtaaa ggagtgcttt
    32761 aaatgaagtt ttcagagttt aagtatgaaa gacccaatta taatagtatg aaaaaagagt
    32821 ttttgagttg tgtagaagat ataaataatt ctcgtaatta taaagagcaa caaaaaaata
    32881 tacataagat taatttatta agaaataaaa tagaaacgtt gtcaaatata gcttcgataa
    32941 gatatagtac agacacattt aataaattct acaaagaaga aaaaaattat tgggatgaat
    33001 atatgccttt gtatgaagaa ttaaattcat atttttataa tgccattgta aattcaaaat
    33061 ttaaatatga tttgataaaa gagtttggag agcaattttt cacaatagta gagtattctt
    33121 taaaaagttt ttccaaagaa ataataagtg aattgcagga agaaaataaa ttgtgttcag
    33181 agtatactag acttttagct tcagctgaga taatgtttga tgggaaaata agaaatttat
    33241 ctggtatggg gaaattcatg tattctaaga atagaaaaac aagagaatta gcaaacaaag
    33301 catattataa tttctttgaa gaaaatgaaa ctaaatttga tgacatattt gataaattgg
    33361 ttaaacttag agataagatg tctaaaaaat taggttttga agattttgta gagcttgggt
    33421 atgttagaat gatgagaagt gactacagag aatatatgat aaaaaatgtt agaaaacaag
    33481 tactaaaata tgttgttcca atggcaaatg agctttatga aaaacaagct aaaagaattg
    33541 gtctagaata tttaagttac atagatgaag gcgtggaatt tttaacagga aatgcaagtt
    33601 taaagggaga ttcaagatac ataattaaaa atggtaaaag gatgtattct gaactgtcaa
    33661 aagaaacaaa tgaatttttt gattttatgt tagaaaatga acttatggat ttagaaacga
    33721 agaaaggaaa aggagctgga gggtattgta cttatatacc agattataag tcaccattca
    33781 ttttttctaa ttttaatcaa actgctgatg atatagatgt attaacacat gaggcaggac
    33841 atgcatttca gttgtatatg tctagatgga ttgatatgcc agaaattaat tttccaacgc
    33901 ttgatagttg tgaaatccat tcaatgagta tggaatttat aacatggccg tggatggatt
    33961 tattttttaa agaagataca gataagtaca aattcactca cttatcatct tcaattaaat
    34021 ttatacctta tggagtaatt gttgatgaat ttcaacacta tatttacaaa aatcctaatg
    34081 tagataagtc aaaacgaaaa gaaatctgga gatttttaga gaaaaaatac ttacctcata
    34141 gaaaatatgg tgataattct tttttagaga gaggttgttg gtggtttaaa caaggacata
    34201 tatttaaaaa tccgttttat tatatagatt atgtattagc tcaaatttgt gcgttacaat
    34261 tttggaaaaa aatgattcaa gatagagatg caggatggaa agattatata aatatctgta
    34321 aagttggagg aacaaaatca tttttagata ttgtgagtat gggaaatttg tattctccat
    34381 ttgatgatgg ctgtattgag tctattatag gtgatgttaa atcttggttt gatgaaataa
    34441 atgacagcaa attataaaaa attatgagaa ttttattgta taaaagtgaa aaattaaaaa
    34501 atatataaaa agtgattatt tgttgtgaaa atagtcttgt ttttaactaa attgataaaa
    34561 taaactaaaa aagatttgta cttaaaaaaa aaagaaaata caagaaatat gcaatatcaa
    34621 catttggaaa aaaaagtaaa aatgtataca aaatacatat aaaaaaacta ttgcaaattt
    34681 tatagaatgt ttatatactt aagtcaacag agatagaaaa aagctattta tagaaaacaa
    34741 aggataaatt gcttaatttt aaattttctg aaaaaaataa taatccggat gaagagtatg
    34801 ggagactgct ttataaaaag cgaccgaagg gacaagttta atcttactta cccaaaagat
    34861 tagatgaaat tctcaggtaa aggtgactgt acttggacgg ggctctgaaa atgattttaa
    34921 cagggaagac aaattgggag atttgttttt cctgtttttt atttatcaag taataaataa
    34981 aagtttgaaa gagagtaaaa aaatgataat aattacgaat aatccaaaag taaaagaaga
    35041 agttcaaggc agagaagttt tgtttaaaga cacaacttat attggaatct tagaagcaag
    35101 tagagatttg atacatgaag gttatgaact tttatctcat ccactctatg ggagtgtaaa
    35161 gccaaatgaa acaccttaca ggactgttat actaaagaaa ggaaatcgtt tggatataaa
    35221 ctctttaacc ttaattgaag aagcaatcat cactgcaagt aaatttcaga ataataaaaa
    35281 gactccaaaa tggacagaaa gtgttcaaga tgattttaga gtaattgatt atgatatatt
    35341 ttataataca atacaaagaa tgcagtatga ataaaaaaaa attgttaaaa agttattaaa
    35401 acagcctaaa tattaaatct aatttaatat taaataaaat gagaaattta attggggagg
    35461 ataagtcaaa atggaaaatg tgtatgactt agtaataatt ggttcaggac cagcagggct
    35521 tgcagcaggt ctttatggag caagagcaaa gttaaaaact ctaatcctag aaaaagacaa
    35581 gactggtgga caaattgtaa taacacatga aattgcaaat tatccagggt cagttccaaa
    35641 tgcaacagga ccaagtttaa tagctagaat ggttgaacag tgtaaagagt ttggagcaga
    35701 aatgctaaga gacaacattg ttgatactga gctagatgga gatataaaag ttttaaaagg
    35761 ggaaaaggca gaatatagag caaaagcagt aataatagga acaggagcaa caccaagaaa
    35821 gattggttgt cctggagaaa aagaacttac tggtaaaggg gtttcatatt gtgcaacttg
    35881 tgatgcagat ttctttgaag attttgaagt atttgttgta ggtggaggag acagtgcatt
    35941 agaagaagca atgtatttaa ctaaatttgc tagaaaagta acaattgtac atagaagaca
    36001 aggatttaga tgtgctaaga gtgttgaaga aaaagcaaaa gctaatccaa agatagagtt
    36061 tttattagat acagtaattg aagaaatcaa aggtgatgga atattagaat cagttgtatt
    36121 taaaaataaa gttactggag aaactcatga atactttgca gatgaagaag atggaacaat
    36181 gggagtattt gtgttcgttg gattagatgc tcaaactgat ttattcaaag gtaaagttga
    36241 tatggatgaa aaaggttaca taataactga tgaagatatg agaactaaca taccaggcgt
    36301 atttgcagca ggagattgta gatctaagac tctaagacag gttgtaactg caactaatga
    36361 tggagcaatt gcatctatag tagctgagaa atacattgat gaaaaatttg ggaactagaa
    36421 tctgtaaatt aagaaatagt gtctgtaaat ttaatgaata atatttaaaa ttaaaattaa
    36481 tatttaaaat taaaataaaa atttcaaggg ggaataagaa aatgttagat ttagataagg
    36541 ctacatttga agaagaagtt ttaaatgcag aaggttttgt atttgttgat ttttggagtg
    36601 aaggttgtga gccttgtaaa gctttaatgc cagatgttca taaattagct gagacttatg
    36661 gggataaaat aaaattctgt aagatggata caacaaaagc tagaagatta gctataaaac
    36721 aaaaagtatt aggtcttcca actatggcta tatacaaaga tggagaaaaa gtagacgaag
    36781 ttactaagga tgatgctaca gttcctaata tagaaaacat gattaaaaaa tatctttaat
    36841 atgttgataa attattaaca ttaaaagaaa aaatctattt ttatctgaag ataagaagaa
    36901 aaaggttttt atgtccaact ttgttaaaaa aataatttta aataaaataa tttttttaca
    36961 ataaatattt tttagtaata aaataaagat ttaaggcata aaaacacaat aatatatctt
    37021 taaaaaaata agataaattg taaaatgata taattttgag aaaaactcaa atgcatatac
    37081 acaaattaaa taacaggagg tgcaagtatg cgtcttgaat tagggaaaat ctttataaaa
    37141 gatattcaat ttggtgatgt aacagaagta aaagatggag tattattcat caataagcaa
    37201 gagatgctac aagaaattgg tggagatgag catattaaat ctatagatat agaattagct
    37261 cgtccaggtg aaagcgtaag aataacacct gtaaaagatg ttattgagcc aagagtaaaa
    37321 gttgaaggta atgggggaat cttccctggt atcatgtcta aagttgacac tgtaggagaa
    37381 ggaaaaactc atgctttaaa aggtgtagct gttgtaacta ctggaaaaat agtaggtttc
    37441 caagaaggta taatagacat gactggagaa ggagctaagt acactccatt ttctaaatta
    37501 aataatgtag tagtaatagc tgaacctatt gatggtttaa aacaatacgc tcatgaaaaa
    37561 gctgttagaa tgataggatt caaagcagca atgtacttag gagaagtagc aagaaatctt
    37621 actccagatg aagtttcagt atatgaaact aaacctcttc ttgaatcaat aaaagaatat
    37681 ccagagcttc caaaagtagg atatgtttac atgcttcaga ctcaaggttt attacatgat
    37741 acttatgtat atggagtaga tgcaaaacaa atagtaccaa ctttattata tccaacagaa
    37801 ttaatggacg gagcaattgt aagtggtaac tgtgtttctg catgtgacaa aaacccaagt
    37861 tatgttcata taaacaatgg ggttgttgaa gacttatatg caagacatgg taaagatata
    37921 aactttgtag gtgtaattat aactaatgaa aatgtttatc tagcagataa agaaagatct
    37981 tcaaactgga cttctaaatt atgtaaatat ttaggattag atgcagttat agtttcacaa
    38041 gaaggttttg gaaatcctga tactgacctt ataatgaact gtaagaagat agaaatgcaa
    38101 ggtgttaaaa cagttatagt tacagatgaa tatgctggac gtgatggagg ttctcaatca
    38161 cttgcagatg cagatgtaag agctgatgct gttgtaacag gtggaaatgc caaccaagtt
    38221 gtagttcttc ctaagttaga taaagttatt ggacatttag aagtagtaga tgtaatagct
    38281 ggtggttctg atggaagttt aagagctgat ggaactattg aagttgaaat ccaagctata
    38341 acaggtgcaa ctaatgaaac aggatttggt catttaactg ctaaaggata ttaagaagta
    38401 ttttattaaa cgattgagta atgttaataa aacatattat agataattat aataagtgtt
    38461 atagatatat aaaaatatat tagaaatata ataaggagga ttattatgag tttacttagt
    38521 aataaaaagg ttcttataat aggtgaccgt gatggtatac caggacctgc gatagaagaa
    38581 tgtgtaaaaa cagtagaagg agcagaggtt gttttctcat ctacagaatg ctttgtctga
    38641 acagctgctg gggctatgga cttagaaaat caaaacagag ttaaagatgc tgctgataaa
    38701 ttcggagctg aaaatgttgt gattttacta ggtgctgctg aagccgaagc tgcaggtctt
    38761 gcagccgaaa cagtaactgc tggagatcca actttcgctg gaccacttgc tggagttgcc
    38821 ttaggattaa gtgtttacca cgttgttgag gaaccaataa aatcattatt tgatgaaagt
    38881 gtatatgaag accaaataag tatgatggaa atggttttag aagttgaaga aatagaagaa
    38941 gaaatgtctg gtataagaga agaattttgt aaattttaat gcctaaaagc aaaaggggtg
    39001 aaactaagag atgggaaaac taaaagcagt acattatatt aatcagttct ttgctggtat
    39061 aggtggagaa gaaaaagctg atactaagcc acatgtggca gaaactttac ctccaataag
    39121 tttacaactt gataaattat taggtgaaga tattgaaata gttggaacag tagtttgtgg
    39181 agatagctat ttcaatgaaa atatagatag tgcaagtgaa gaagttttat caatggtaaa
    39241 aggttttgaa ccacaacttt tcatagctgg tcctgcattt aatgctggta gatatggggt
    39301 tgctgctgga acaataacta aagttgtaaa agatgctttg aatataccag ctttaacagg
    39361 tatgtatgtt gaaaatccag gagcagatat gttcaaaaag gatgtttatg tagtagaaac
    39421 ttctgattct gcagcaggta tgagaaaggc acttcctaag atagctaaac ttgcagtaaa
    39481 acttgctaat ggagaagaaa ttggaactcc taaagatgaa ggatacatag ctagaggaat
    39541 aagagttaac tacttccatg aagacagagg ttctaagaga gctgttgaca tgttagttaa
    39601 gaaaataaaa ggtgaaccat ttgaaactga atacccaatg ccaaactttg atagagttga
    39661 cccaagtaaa gctgtaaaag atttatcaaa atgtaaaata gctttagtta cttctggtgg
    39721 tatagttcca aaaggaaatc cagatagaat agagtcttct tcagcttcta aatatggaac
    39781 ttattctata gcaggagtta tggatttaac agaagagact tatgaaactg cacatggtgg
    39841 atatgaccca gtgtatgcaa atttagatgc agatagagta ttacctgttg atgttcttag
    39901 agatttagaa aaagaaggtg taattggaaa attacatgag actttctata caactgtagg
    39961 taatggtaca tctgttgcaa actctaaaaa atatgcttct gaaattggag cagcattagt
    40021 ggctgatggt gtagatgcag taatattaac ttctacatga ggtacttgta ctcgttgcgg
    40081 tgcaacgatg gtaaaagaaa tagaaaaaac tggacttcca gtagttcata tgtgtacagt
    40141 agtacctatt tcattaacag taggggctaa tagaatagtt ccaactatag caatacctca
    40201 tccacttgga aatccagcgc ttgaccctac agaagaaaaa gccctaagaa gaggccttgt
    40261 agaaaaagca ttaaatgctt taactacaga agtagatggt caaacagtat ttgaaaaata
    40321 aaaataacac acacatatat tatatagata aaaatataaa cacacactaa aaataaaaaa
    40381 taactataca caaaaaaata atatagattt catgaatgga taaattggag ttattcattc
    40441 atgaaatctt aaaaaatgcc aaaatacata aacaataata gaatcaaata tacaataaaa
    40501 tacaatgatt agagctttta ataagtttaa taagattaaa aaataagtgt tcataaaatt
    40561 tatggaggtg cacaaaatga cttatccagt tttaaaaggg gcaggctatg tacttattca
    40621 tactccagat atgatagtgc aaaatggaag tacttgtaca gttgaaagag caacaaatcc
    40681 agattcagaa tttttaaaag aagtaagtaa tcatataaga agttatgaag atgtagttaa
    40741 ctacatgcca aatcaagttt atataggaaa tagaagacca gaagaattaa gagatttacc
    40801 aatgccatgg tgtgaacaaa agattgaggg aactagaaat ggtaagtttg gagaaataat
    40861 gcctcaagat gagttcatag ctttaatgca aataagtgat gcatttgatt tagtaaaatt
    40921 atcacaagaa tttattgatg aagtaaagcc aaaaatcgaa aataactacc ctgaaattgc
    40981 accatttgta ggtaaattaa agggtgatga tatagaagaa ggtaaagaat tagtagcaac
    41041 acacatagct gaaggattat accatgatgg aaaatttgtt ggttatgtaa aaagagcaca
    41101 tgatgtagat gttaacttaa atgcccatac aatgtttgaa aatctagtag taaaagcatc
    41161 tggagtttta tctgctattc aaatgctaag acatagcaaa atagaccctg ctgaaataga
    41221 ttatgttatt gagtgttcag aagaagcttg tggagatata aaccaaagag gtggaggaaa
    41281 ctttgctaaa tcaatagctg agatagcagg acttcaaaat gcaactggtt ctgacacaag
    41341 aggattttgt gcagcaccaa ctcatgcatt aattcaagca gcagctttag taaaagctgg
    41401 catacataaa aatgtaatgg tagtagcagg tggagcaagt gctaaacttg gaatgaatgc
    41461 taaagaccat gttaaaaaag gtcttcctgt acttgaagat gttgttggag gatttgcagt
    41521 acttgtatct gaaaatgatg gtgtaaatcc agttataaga actgatttaa caggtaagca
    41581 tactgttgga actggttctt caccacaagc agttatgaca gcacttataa cttcaggtct
    41641 tgatagagct aatttaaaaa taacagatgt tgatgtgtat tcagttgaaa tgcaaaaccc
    41701 agatataact aagccagcag gagcaggaga tgttccagaa gcaaactaca aaatgatagg
    41761 ggcacttgct gttaaacgtg gagacttaga aaagaaagaa ttgaaagatt ttgtttctaa
    41821 caaaggatta ccaggatggg caccaactca aggacatata ccatcaggag ctccttatat
    41881 aggattttta atagatgatt taactacagg aaatagaaat agagctatga tagttggaaa
    41941 aggtagttta ttcttaggaa gaatgactaa cttatttgat ggagtatctt ttatagctga
    42001 aagaaataca ggtgttactg aagagacttc aggaatatct aaggatgaaa ttaagaagat
    42061 aatagctgaa tctatgaaaa aactagcatt agatatgtta gaagaatagg ggtgaggata
    42121 tgtcaaaaaa agtaatcgca gatgtattct tagaagtagc taatgcaata gaaagcggcg
    42181 aatttggcaa aaaagtaaaa attggtgtta ctacacttgg aagtgaacat ggtgtagaaa
    42241 acatggttaa tggtgcacaa ttagcaaaat ctaatttatt tgatattgtg cttattggac
    42301 caaaagtgga aactgacctt gaagtagttg aagttaatga tgaaaaagaa atgcatgcaa
    42361 aaatggaaga attattagat tcaggatata ttgatgcttg tgttactatg cattataatt
    42421 ttccaatagg tgtatctaca gtaggtagag taataactcc agcaaaagga aaagaaatga
    42481 tacttgcaac aacaacagga acaagtgcta ctaatagaat agaggcaatg gtaagaaatg
    42541 ccatttatgg tattgctaca gctaaatcaa tgggtaacaa atgcccaaaa gttggaatac
    42601 ttaatgttga tggagcaaga caagttgaga agtgcttaaa agaattaaaa gataatggat
    42661 atgacatgga gtttgcggat tcaattagag cagatggtgg atgtgtaatg agaggtaatg
    42721 atttacttgt aggtgcacct gatgttatgg ttactgatac attatctgga aatatattta
    42781 tgaaagtatt ttcttcatat actacaggtg gagattatga agctcaaggc tttggatacg
    42841 gacctggagt tggagaggac tatgatagaa aggtacttat agtatcaaga gcatcaggtt
    42901 ctccggtagt agcaaatgct ttaaaatacg cttatgatgt tgtaaaggga gatataagta
    42961 atgttgcaag aaatgaattt gcaaaggtta aaaaagcaaa atttgatgac attatatcct
    43021 ctcttactaa aaaagaagtt aaagctgaaa aagtagaagt taaaatgcca gataaagaaa
    43081 ttgttactcg tcaaatagct ggtgttgata taatggattt agaagatgca gtatctgagt
    43141 tatggaaaaa cggaatctat gctgaaagtg gtatgggttg tacaggtcca atagttttag
    43201 taaatgaagc taaaggagac ttagcagttg aaactttagt taaagctgga tatactgcaa
    43261 aataagtaca ttttttatat gtaaataaga acatatagtt ataattttat tgattataat
    43321 tatatgttct ttttatttta tatcttgtca atatttatat attaacacaa tccatttatt
    43381 tgattctcta gctaatttat tatatttatt caattaaaat taagctttct aactaaataa
    43441 aaactaatga agtattaaaa tgaaattgat aaaatatgaa aaaattttag gaataaagta
    43501 tctgttagat aaaaataaga ttaattagtg atataatata attaagataa aatttattat
    43561 ttggaggtaa aatcatgagc agagtaaaaa atgtagtaga attgttggaa actaaaggtg
    43621 ttgatgcact atatctaaca aagaaaacta atgtaaacta tataagtggt tttcctgatg
    43681 aagaagcata tgcagtgatt tgcaaagatg gaaacttttt agttactgat agtagatata
    43741 tggagcttgc agaaaaggtt tgcaaagatt ttgaaattat aaattggcat aattttgata
    43801 gaagtgtggc aaaggcagtt aaaagtgtat gtgataaagt gggtataaag aaacttggat
    43861 ttgaaagaac taatatagtg tttgataaat atgaagaact taaaaatctg attgagaagg
    43921 ataatggaga attaatacct acagaaaata ttgtagagac tttgagatat gtaaaagaca
    43981 aagatgaaat caaaaataca agaaaagctt gtgaaatagc ggataaggca ttagaagaat
    44041 tgattccaca tataaaagct ggagttagcg aaattgaact ggctacaagg ttagagtact
    44101 ttatgaaaat gaacggagca caaaatatag ggtttgaaac tatactgata tcaggagcaa
    44161 agacttcatt gcttcatggt aagcctagtg ataagattat agaaaaaggt gattttgtac
    44221 ttatagacta tggtgctatg tataatggct atatatctga tacaactaga acttttatag
    44281 ttggaggagc ttctgaaaag caattagaaa tatataattt agttaaggaa gctcaaaatg
    44341 taggggttga gaacatgaaa gctggtgtac atgcgacaat tccagatgct gagataagaa
    44401 aagttgtcaa aaaatatgaa gactattact atcaaggtat aggacatgga gtcggtagag
    44461 atgttcatga agaacctttc attggtaatt atggtgataa aatcatagaa gagggatgta
    44521 taataacaat ggaaccaggt atttatttcc ctggatgggg tggagttaga atagaagata
    44581 ctgttttgat tactaaaaat ggtccagaaa gacttactaa attccctaaa gatttgatga
    44641 ttttagacaa ataatttaat ttatatatat ttttttacat aaaatataac ataatctcac
    44701 tattaagctc tatttacata ttatagtaaa gagggcttaa ttttattgtg agaggtgata
    44761 gtatatatgt ataaaaaaca taaatttata aaaaatataa aaaaagcctg gtataaaatc
    44821 aaattaattg atagatgcct tataattgta atggcaatat taatgtttca atctatatat
    44881 aacttatttg ttaatgaagt aaattcacaa gatactacaa ctattgatgt agtagtaaga
    44941 accacttcag cagctatatt tgggtatttt ttaagtgcta attttataaa gagaccttta
    45001 aggaagtata caaatactga tgtatcttca aatcttttta tagataataa tttatcccca
    45061 aaaggtcaag agtctaatca aaataatata atgaatgtca aaaataccat tggatttact
    45121 tcagaagctg ataattatga aaagaaaata cctattaata ataatgaagg ttttgaagaa
    45181 ggagaaacta gtgaattgca aattattata gctactgtaa tttgcatagt agcattaaca
    45241 gtactttttg ttgtaagaaa ttttacaact acaacatcag cttctttagg tactatttca
    45301 cagatgagag attttgtctc aggatgcgtg ggttttttgc taggttgtcc aagtaaacct
    45361 gattaaaaaa gtattatcaa taaaaggtat tttaaaaagt atcagtataa taatatttag
    45421 atttaaatgt atacaattat aattctgtaa cattctatat tgtattttta tactgatact
    45481 ctaaactata ctatttatta aaatatttta acattgtatt taaacaaaat attatatctg
    45541 tataatataa atttagttta tatgaataga tgccatatac tcaataaaaa gtttcatact
    45601 atgagatatg tattgatttc ttctccaaag aaccccaata tttgcagtaa ttgcacgttc
    45661 taatggtatt gaacagagat tttctgtatt ttgaaatatt tctttataca atattgttga
    45721 agccaagtca ttttctagta aataacgtat ggtagaaagt tgatttgagt gtaaaattat
    45781 atttggctta gctttttcaa gtctttttgt aataatctta tagtgataag aaccttcaga
    45841 taagattaca aaaggtacat tttttaacat ataattcgat ataataggat gttttgccaa
    45901 ttcatttttg ggatttgtaa ctaagtataa ttctgtttta tagattgtct ttgaatctat
    45961 atcatcataa atatcactgt caattatacc aatacaaaaa tcaagtgtag attcttcaat
    46021 cattttagct ccaacaaatg ttggaacttc aaaaatttta agctctatat ctggataaat
    46081 tacattaaac ctaggaagta tttttgaaag caaaaacgta cctaaaactg taggaatacc
    46141 tattttgaga gaagcttttc tcttttttcc taaatcaagt gcgtcacatt gaaaatcctc
    46201 aaattgtttt ataaaatgtt ttgacttgtc taaaaaaatt tttccttcag gcgttaactc
    46261 tattttatta cctattctgt aaaaaagttc aaagccaagt tctttttcta attctttaat
    46321 tgctaatgtt atggatggtt gagaaatatg aatactttcc gcagccttag tcatgttttt
    46381 atatttacag acagtttgaa aatagtataa atagtttata ttcatttggt attagttcct
    46441 ttcatttaca tattagtgac aagtatataa ttaacaatag cataagtttt gtatattgtt
    46501 gtaaaaaaat agaatagttt taaactatca tagcataagt ttttgatatt ttcaatctat
    46561 taagaatagt gctattatta aattaacaaa agagaatagc tggtatggtt tagagtaaat
    46621 caatctatat tacagttata tcaacgaata tcaaaaaatt atctattaaa aaataaaaat
    46681 tatttttaca attaaattgt taattaaatc ataaagaaaa aagtgatatt aacaagataa
    46741 aattttttta atcagaaatg ttaatttaat aacaaaatag agtattgggg agaaaggaga
    46801 aatatatttt ttaataatat ttgttaattt aataacgaaa aatgaaaggg agtgatttag
    46861 tgaagtttga attgatggat tttttaatga atccttttgt ccttatgttt gctgcagtaa
    46921 ttacaggaat tttatttgga aaaattaaat ttgggaagtt taattttggg gtatcaggag
    46981 cattatttac aggattattt attggatggc ttgcatatag cttggggaat ctaataatag
    47041 caaaagggga aacagcagca ggatataagg cagcaactgt aatgatgggg aatggaatta
    47101 tttcttctga cttctttgat ttctttttaa taatatttgt tgcagcagtt ggtctattgg
    47161 cagcaaaaga tatgaaagct gtattaaaga agtatggagc aagatttgta attttaggag
    47221 ttcttataac ttttataggt ggctctatga cttatgcaat gactttacta tcaagtgata
    47281 aaggaagtag tgcttatgaa gtttctggcg tttacacagg agcattaaca agttcgcctg
    47341 gattagctgc tgctttagaa acagctggta aacatgcaga agatgtatca aaagaatttg
    47401 aaaaagcttc aataaaagat aaaaaagaaa ttttaaaagt agtcgaccca gaaggcaaat
    47461 tggatgtgaa tacaactaca tcactgactc aagagcaaat agataagtat attgcatatg
    47521 ctgaagctgg tgttggtata ggtcatgcag tcgcatatcc ttttggagtt ttaatagtaa
    47581 tcttaggtgt aaatttcctt ccaaaattat ttaggatgga cctaaaagaa gaaagaagaa
    47641 aatatgagaa ggaaatgaag gaagcaagag atagtgtttc tggtaaaacg ataccagaag
    47701 ttccatttaa tataataaca tttttcttga catgtttagc tggatactta gttggaggaa
    47761 tacatgtatt tatgggacca ctagggtact tcacactagg tgcaacagga ggttcactaa
    47821 ttgtatctct agttcttgga tatataggta agataggggt agtaaatttc agaatggaag
    47881 aaaaggtttt aaatatttta aaacaaatag ggctagtgtt tttcttagca atagttggat
    47941 taagatatgg tggaaaagta gttgattcaa ttatgacatc tggtatgcac ctagccttag
    48001 tagcaatagc agtaggtgtt acagctatga tgataggatt cttagttggc aaatacgtat
    48061 ttaaattaaa ttggatttta ttatctggag ctgtctgtgg tggtatgaca tcaacaccag
    48121 gtcttggagc tgctgttgat gctcttgata gtgatgaccc agcagcaggt tatggtgcta
    48181 cgtatccatt tgcattatta actaaagtta tattggttat agttttacac aaacttccaa
    48241 tgtaaataag attttatatg gggggatatt tatgaataat gaaggagcat ttgaagaatt
    48301 aagtggaaga ttaagaaata aagaattgtg tgatttaata atgaatgcag atgaagctgc
    48361 taaaattata gaggatggca tggttattgg agttagtgga tttacacctt caggctatcc
    48421 aaaagcagta ccattagcag tttcagaaag agctaaaagt ggagaaaaga taaaattaac
    48481 cgtatattca ggagcatctt taggtccaga agttgatgga gcatggtcag aagcaggtat
    48541 aattgaaaga agacttcctt atcaaactaa ttcaatactt agaaataata ttaataaagg
    48601 tgttgttgat tatatagata tgcacctaag tcattctact caatttttaa attatggaac
    48661 tatacctaaa gtagatgtag ctatagtaga agcacttgca ataactgaag aagggaatat
    48721 tataccaact agtgggatag gtaattctcc atcttttata aaaagtgcag ataaagtaat
    48781 agtagagata aatcttgcaa aaccaatgga aatggaaggt atggcagata tatatattac
    48841 ggaaaatcca ccaaatagaa aaccaataga aataaatcat cctaaggata gaattggaac
    48901 aacatatata ccttgtggtt tggataaaat tgcaggagta gtaattacca atatgcaaga
    48961 taagacccgt ccattggggg ttgtagatga agcttcgaaa aaaatatcaa ataatattat
    49021 tgctttttta agagaagaag taaagtcagg cagattatca aagaatttac ttcctcttca
    49081 atctggtgta ggaagtgtag caaatgcagt attatatgga ttatgtgaat ctgaatttga
    49141 aaatttaact tgttatacag aggttgtaca ggactctatg ttggatttaa taagaatggg
    49201 taaagttaca atggcatcta ctacatctgt aagtccatct ccagaaggat taataaaatt
    49261 tgaaaaagat attgattttt ttaaggataa gattatatta agacctcaag aaattagtaa
    49321 caatccagaa atagccagaa gaattggtgt aattgcaatg aacactgcaa ttgaagttga
    49381 tatttatgga aatgtaaatt ctactcacat aatggggtca aagatgatga atggaattgg
    49441 tggttctggt gattttgcta gaaatggagc aataactata tttagtactg agtcaattgc
    49501 aaaaaatggt gatatatcat caatagtacc tatggtatct cacgtagacc acactgaaca
    49561 tgatgtaatg gtaattgtaa cagaacaagg atatgctgat ttaagaggtc ttgcacctag
    49621 agaaagagct ataaaaataa tagaaaattg tgcccatcca gattataaag aacaacttag
    49681 ggattattta aatagagctt gtaaaagtgg agcaaaacaa acacctcaca tattggacga
    49741 agctttatca tggcatagta aatttatgag tacaggtaca atgaaaaagg ctgaaacttt
    49801 taaaagtgca ttataaaata tttaataaat tggaggtaga ttttaaatgg aaaaagcagt
    49861 ggaaaacttt gaagatttaa gtaaggaata cattaatggt tatattgaga gagcaagaaa
    49921 agctcaaaga gagtttgaat gttatactca agaacaagta gataaaatag taaaaatagt
    49981 tggaaaagta gtgtattata atgctgaata tttagctaaa cttgctgtag aagagactgg
    50041 aatgggagta tatgaagata aggtagctaa aaataaaagc aaagcaaaag ttatatataa
    50101 caatttaaaa gataaaaaat cagttggtat aattgatata gatagagaaa ctggaataac
    50161 aaaggtagct aaaccagttg gagtagtagc ggcaataact ccttgtacaa atccaatcgt
    50221 tacacctatg agcaatgcaa tgtttgcact taagggaaga aatgcaatta ttatcacacc
    50281 tcatcataaa gcaattggat gtagtacaaa aactgtagag atgattaatg aagaattaga
    50341 aaaaatagga gctccagaaa atttaataca aatacttgac caacaatcaa gagaaaatac
    50401 aagaaattta atttcatcag cagatgtagt aattgccact ggaggaatgg gaatggtaaa
    50461 agctgcgtac tcaagtggaa aaccagcact tggtgtaggg gcaggaaatg ttcaatgtat
    50521 catagataga gatgtagaca ttaaagaagc agtacctaaa atcatagcag gaagaatttt
    50581 tgataatggt atcatttgtt caggtgaaca gtcagtaata gtagcagaag aaatgtttga
    50641 taaaataatg gatgaattta aaaataataa aggttttata gttagagata aagtacaaaa
    50701 agaagctttc agaaatgcta tgtttgtaaa taaatctatg aataaagatg cagtaggtca
    50761 atcagttcat acaattgcaa aaattgcagg tgttgagata ccagaagata caaaaataat
    50821 agtaatagaa gctgatggac caggagaaga ggatattatt gcaaaagaaa aaatgtgtcc
    50881 agttatatct gcatacaagt ataaaagttt tgaagaaggt gtagctattg caaaagcaaa
    50941 tttaaatgta gaaggaaaag gacatagtgt atctatacat tcaaatacag ttaaaaatat
    51001 agaatatgca ggagaaaata tagaagtatc aagatttgtt attaatcaat gttgtgctac
    51061 tagtgctgga ggaagtttct ttaatggtct tgcacctact aatactctag gttgtggttc
    51121 ttggggaaat aacagcatct ctgaaaatct tgattataag catctaatta atatttctag
    51181 aattgcttat tatatgccag aaaatgaagt ccctacagat gaagaacttt ggggataaaa
    51241 tttagacaaa aaatattcat tctaaattaa agtaggaata tattttaatt tagaatgaat
    51301 ttaagacata aattaaattt aaattagttt attggactaa atttaaaata ttaagagaca
    51361 tatagaagaa ggaagtatta taatttaaaa taaataaaaa aatctataaa agagaaggag
    51421 tggttttatt atggcattaa tgacaggagc tcaatatatt gaaagtttga gaaaattaaa
    51481 tactaaggtt tatatgtttg gtgaagaggt taagaattgg gttgaccatc ctatgattag
    51541 accatctata aattgtgtag cagcaactta tgacttagct catgacccag aatatgcaga
    51601 tttaatgaca gttacttcaa atatcacagg tgaaaaaata aatagatttg gtcatcttca
    51661 tcaaagtgtt gatgatttga taaaaaaagt aaaaatgcaa agactatgtg gtcaaaaaac
    51721 agcttcttgt ttccaaagat gtgttggtat ggatgcgttt aatgcagtgt attcaacaac
    51781 atttgagtgt gataaagccc atggaactaa ttatcatgat aattttgtaa aatacttaac
    51841 ttatatacaa gaaaacgatt tagtagttga tggagctatg actgacccta agggagatag
    51901 aagtctatca cctagtgctc aacctgaccc agatatgttc cttcatatag tagaaagaag
    51961 agaagatggg ataattgtaa gaggagcaaa ggcacatcaa actggttcaa taaattcaca
    52021 tgagcacctt ataatgccta ctataagtat gactgaagca gataaagact acgctgtatc
    52081 atttgcagtt ccttcagatg ctgaaggagt gtttatgatt tatggaagac aatcttgtga
    52141 cactagaaaa ttagaagaag gtgcagatgt tgatttagga aataaggagt ttggaggtca
    52201 agaagcttta gtagtatttg ataatgtatt tgttccaaat gatagaattt tcttatgtgg
    52261 agaatgggat ttctctggta tgttagtaga gagatttgca ggataccata gacaaagtta
    52321 tggtggatgt aaagtaggag taggtgatgt aataatagga gcagcagctt tagcagctga
    52381 ttataatgga gcaaacaaag cttcacatat aaaagataaa ctaatagaaa tgactcacct
    52441 taatgaaagc ttatattgct gtggtatagc atgttcatca gaaggtcaca aaacagaagc
    52501 tggaaactat caaatagatt tacttcttgc aaatgtgtgt aaacaaaatg taactagatt
    52561 tccttatgaa atagtaagac ttgcagaaga tatagctgga gggcttatgg ttactatgcc
    52621 ttcagaaaaa gactttaaat cagaccttaa agttggaaca agtggaatga ctattggcga
    52681 agtatgtaac aagtatttta aagcttcttc agtggcttca acagaagaaa gaatgagaat
    52741 attaagattc ttagaaaata tatgccttgg ttcatctgct gttggttata gaactgagtc
    52801 aatgcatggg gcaggttcac cacaagctca aagaataatg atttcaagac aaggaaacat
    52861 aaatcaaaag aaagaattag ctaagaaaat tgcgggaata aaaaaagagg aagctttaaa
    52921 tttataaaaa gttgatatat aaagggaaat tatatattaa tgtgtattaa ttaatgaaaa
    52981 aatatgtagt ataagagata gttataaaat tatggtggtt tttagctaag taaagaaatt
    53041 tttaataagg agaatttaca catgacctgt ggagttagat tttgtggggg ctgtaaccct
    53101 agatacgaaa gagggaaggc tcttacaata atcaaagagc acttcaatgg tagggtagat
    53161 tttagtatag cacaagagaa cgtcgagtat gatttgctac ttataattgg aggatgcgca
    53221 actctatgcg catcctatca acaatataaa gtgaaaaatg aatgtgttaa gatgtgggat
    53281 tttagccata tagaaagagt tataaatgtg attgaatcag caatttgtga aacttaaaaa
    53341 agctaaatgg ggggatttca ttgagttggc aagaattgta tcaaagtaaa ttatgtagtg
    53401 ctacagaagc tgtaaaacag attaaaaacg gtgatactgt agtatttgca cattgtgtag
    53461 gtgaacctcc tgcactagta gaggctatga ttgaaaatgc tgaacaatat aaagatgttg
    53521 agattaaaca tatggtaagc ttgggtagtg gtggatatac tgctaaggga atggaagctc
    53581 attttagagt aaatccaatg tttgtaagtg gaaatgtaag aaaggcaatt gaaaatggag
    53641 atggtgattt tacacctgca ttcttccatg aagtaccaaa gttgcttaga gaaaaaagat
    53701 taaaatgtga tgttgtttta gcacaggtaa ctccaccaga tgaacatggg tattgtagct
    53761 taggaacatc agttgattat acttatgaag ccattaaaac tgctagaaca gtaattgttc
    53821 aagtgaatga ccagtttcct agaacctatg gtgaggtagt ccatgtatca gagtttgact
    53881 atatagtgga aaaatcacaa cctttatttg aactacaacc tgcaaagatt ggagaagtag
    53941 aagaagcaat tggtaaaaat tgtgcttcat taattgaaga tggttctact ttacagctag
    54001 ggattggtgg gataccagat gcagttatgt tatttttaac tgataaaaag gatttaggga
    54061 ttcattcaga aatgatttca gatgggactt tggcccttta tgaaaaaggt gttataaatg
    54121 gtaaatataa aaattttgat aaagaaaaaa tgacagttac cttcttaatg ggtactaaaa
    54181 aattatatga ctttgcaaat aataaccctg cagtagaggt aaaaccagta gactatgtga
    54241 atcatccagc aattataatg aaacaacata agatggtttc tataaattct gctatacaag
    54301 ttgatttaat gggacaggta gttgcagagg ctatgggact tagacaattt agtggtgttg
    54361 gaggtcaagt tgactttata cgtggagtgt ctatgggtga agatggaaag gcaattatag
    54421 ctatgccttc aataactacg aaaaaagatg gtacagtaat ttcaaaaatc gtgtctattg
    54481 tggatgaagg tgcacctata acgacatcaa gaaatgatgt tgactatatt gtaacagaat
    54541 acggtatagc agaattaaaa ggaaaatctc ttagagaaag agcgagaaat ttaataaata
    54601 tagctcatcc aagtgtaaga gaaagtctag cagtagaatt tgaaaagaga tttaaggaga
    54661 aatattaata atagaggggt gttaataatg gaagcactta gagtagttcc aaagatattt
    54721 tactttgata catttaaaga atttaatgaa gaatttaaaa taggaaaaaa tgatttagta
    54781 attactaatg agtttatata tgagccatat atgaaacctc ttggaataga tacaaattta
    54841 atttttcaag aaaagtttgg aacaggtgaa ccatctgatg aaatgataga ctccatgaca
    54901 aaggaaatga agaaatacaa ttttgataga attattgcat ttggaggagg aacaatagtt
    54961 gatatatgta agatattagc acttgatgtt ccagaaaagt ctattgattt atttgaagga
    55021 gaagtatcac ctaaaaaagt aaaagagtta gtagtagttc ctacaacatg tggtacaggt
    55081 agtgaagtaa caaatgtagc tattgcagag ttaaaatcta aacatactaa aaaggggctt
    55141 gcagtagaag aaacatatgc agactatgca gtgttaattc cagagacagt aaaagggtta
    55201 ccttacaaat tctttgttac aagttcggta gatgctctta tacatgctat tgagtcttat
    55261 ctttctccaa aagcaagtcc atttacagag atgtattctc tacaagcaat aaaaatgatt
    55321 atggatgggt ataagaagat agttgataaa ggagaagaag agagatttaa tcatcttaga
    55381 gactttgtac ttgcatcaaa ttatgcagga attgcttttg gaaatgctgg ttgtgcagca
    55441 gttcatgcac tatcttattc aataggtgga gctttccatg ttgcacatgg tgaagcaaat
    55501 tatcagttct ttactgaagt atttaagatg tattctagaa aaaaacctaa tggaaaaatt
    55561 ataaaatgta caaaaatttt agcagatgcc cttgaatgtg accctaactg tgatgtttat
    55621 ggagaattag aaaagttttt aaataaatta atagctaaaa aagctttgag agaatatgga
    55681 atggtggaaa gtcagataga tgaatttaca gatagtacaa tagcaaatca acaacgacta
    55741 cttgctaata attatgtaga gcttagtaga gaggaaataa gagagatatt tgcaaatctt
    55801 tattaataca attttttatt tatatgtata gtcaacataa acaatgctaa ttatatttat
    55861 gtacaaataa aaataaggga acttaaattt taattaaagt taagttctct tatttttata
    55921 tggagttaaa tataagtata tttttaattt aaaatatgct tatatttaag tctattactt
    55981 tatttgaaac aatttgtaga atttcaaatt ccttgacagt aataagtaag taattgtata
    56041 atcaaactgc aatatattaa taatattagt gaaaatgaaa ggattataaa atatgtataa
    56101 atcagaaaat ttttcaaaaa aatctgtatt aataaattca tttttaagta aatttttaaa
    56161 aataattgga tggggtttgg taagcttatt tacattatca gccttagtac tttcaactat
    56221 ttccattata attggatggg ctgtaatact tcctattcaa gtatgtgcag tatttttact
    56281 tataggagga gtttgtattt ttaaaggtaa gagattagga gaccaaattt ctcgttataa
    56341 aaaatattgt acaattataa acaatagaaa tattattcca gtagaactta ttgcagaaaa
    56401 cacatctaaa tcattaaatt ttataataaa agatgtacaa aagatgatag acaaaaacta
    56461 ctttataaat acttatattg ataaaagaaa taatcagatt gtgttaacaa atgaagattt
    56521 tgttccacca agatatgaag atgtagcata tgaagtcaaa gaagaagaaa agactgatga
    56581 atccaatgaa gttgatacaa ttataaataa aggaatgaat tatctaacac aaataaaaga
    56641 agctaataaa aatattaaat cagaatcaat gggcgataaa attgtacaag tagaagatgt
    56701 tacaagtaaa atatttgatg ttgtaaaaca tgacccatca aaacttactc aaatacaaaa
    56761 atttatggat tattatcttc caaccacttt aaaactatta aattcatatc atacattgga
    56821 agaacaagga attgatagag aaaatataac aacaactatg gaaagtattg aaaatacaat
    56881 gaatacgatt gtagtagctt ttgaaaatca attggactat ctgtttgaag atgaagccat
    56941 tgatatttct acagatatta ctgttttaga gaatatgtta gtccaagaag gattaacgag
    57001 tggtaaattt taacttcaat agaaaaaata ttctgttatt tttaaacaat taattagtca
    57061 taaagtataa aatgtgtatt atataagtta atcagtactt tatgaaggaa gaggagagaa
    57121 agatacaatg aataatttag atgatatacc agttatgcca actttgacac ttgacccatt
    57181 tggagaagaa tcaaacacta atgatataga taattctgac ttattaatga aaaaggatga
    57241 aaaagaccca gaagaagaaa aactgtctga atctgaacgc aagatggtaa aggaatttgc
    57301 ggaaaaaata gatattacaa atacaaatat gattttgcaa tatggagctg gtgctcaaaa
    57361 aaaggtagca agtttttctg aaacagcttt aaagagtgta aagacaagag atttaggaga
    57421 agttggagat atgcttacaa atctagttac tgatttaaaa gcattttcag cagatgaaaa
    57481 agaacaaagt ggttttttag gaatttttaa aaaggcaaat aataaaattt caaatttaaa
    57541 aactaagtat gatagtgcag aggtaaatgt ggataaagta agcaaagagc ttcaaaagca
    57601 tcaggttaaa atattgaaag atatagcaat gcttgataag atgtatgaat tgaacttagc
    57661 ttactcaaaa gagcttacta tgtatattat agcaggaaaa caaaaattaa aggatatgaa
    57721 agaatatgag atgccaaagt tgagagaaaa agctcgttta tctggttcaa cagaagatgc
    57781 tcaatctgta aatgatatgg tttcactttg tgacagattt gaaaagaaga ttcatgactt
    57841 agaattaact agaatggtat cgcttcaaat ggctcctcag ataagattgg ttcaaaatag
    57901 taataatctg atggcagaaa agattcaatc aactatagta aataccattc cattatggaa
    57961 aaatcaaata gtgcttgctc ttggaatttc tcacttaaat caagctatga aagcacagcg
    58021 tgaagttagt aatatgacaa atgagctttt attaaagaat gcagaaactt tgaagatggg
    58081 aacaatagaa acagcaaaag aatcagaaag aggaattgta gatatagaca caattaagaa
    58141 aactaatcaa tctctaatat ctactattga tgaggtagtt aagatacaac atgatggtag
    58201 aataaagaga caagaagcag aagttgaatt atcaaaaata gaaaatgaac ttaaaagcaa
    58261 gcttcttgaa tttacagtta aataaaaatt atactaagat aaaaagagac tgtctcaaaa
    58321 ttggatatgt ccctgtcaag tagacagact taaaaaaggc tatctttact cggaatgagt
    58381 tcgatattca atcggactca ttccgttttt taattgtatt ctttcattat tataaaaata
    58441 aatataatca tttattagac taatcatttc ctttggatct gtagtatcaa ttaaatatat
    58501 taattcagat ttaaaatgac tgaaaaaact ttctatagga gcattatccc agcagttgcc
    58561 ccttcgggac attgattgta taataccatt atccttaagc cttttagagt aagatctact
    58621 tgtatattgt gaaccttgat ctgtatgtaa aatacaatct ttagctaaat tcatatttat
    58681 tagttgattt actgtattat taactaattt agtatccatt tttgtactta tctcatatgc
    58741 cactatttca ccattaaata aatctttggc tacattcata tataagaatt ttttaccgat
    58801 aggtatgtat gttatatcca tacaaatttt ttctaatggt tgattagctc taaattcacg
    58861 atttaatata ttatcatata tctcatatga tttaaactta cgtctatata ctttctttct
    58921 aataatagat ttaataccta gttctttcat caacctatat actctcttat gattaatagg
    58981 ggtatcaagt attttattta aataagtaca aattcttttt ctaccataag ttcctctata
    59041 ttttttatgt atttcaatta tataatcctt aataattcta tctttgatac ccctatcgga
    59101 agatttttta gaataactta gccatttata gtaaccgctt cttgacacac ttatcaactt
    59161 acacatacta gaaatactat acttcctaga cagaagttta attgttttaa atttatcgct
    59221 tactttgact tgtccaatag ggtacttaac ttttttaaga attcattctc catgcgtaag
    59281 tacttcaatt cttcttcaac agatttaaat tttctattat cattttctag actaatattt
    59341 ttaaatctgc ccctagtttc atcatcaaat gcagttttgc ctttattttt ataatctttt
    59401 acccagtttt gaacttgtgt tttgcttctt atattcagca tctcagcaat tttgtatgat
    59461 gagtatcctt cttttatata taagtttaca gcttttagct taagttcttt gctatatttt
    59521 ttgtgttttt tagacataga aaaaccccct tagagtatac gctttttaga cctattataa
    59581 tagcctttta tttaaatgtc tactataagg ggattatact aaaatagaga taagtctctt
    59641 tttcattgtt taaatgatta aagtatattt atattataaa tttctattat cttttaacat
    59701 aacatcatga gctccacctt caactatact agtagaagat acaagtgtaa gtttagcatt
    59761 tttttgaagt tcaggaatgc taagtgctcc acagttacac atagtagaac gaactttact
    59821 taaagaaaga gttacattgt ctttcaaaga accagcataa ggaacataag agtcaacacc
    59881 ttcttcaaaa gaaagtttct tatctccacc aaggtcatat ctttgccagt ttctagcacg
    59941 agcagaacct tctccccaat actctttcat ataactacca tttatattaa ctttgttagt
    60001 tggactctca tcaaaacgag agaagtatct accaagcatt ataaaatctg cacccatagc
    60061 taaagctaaa gttatatgat ggtcataaac gataccacca tcagaacaaa ttggaatata
    60121 aatacctgtt ttttcaaagt attcgtccct agcttgagca acttcaatta tagaagtagc
    60181 ttgtccacgt cctatacctt tttgttcacg agttatacat atagaaccac caccaatacc
    60241 aactttaacg aagtcagcac cagcttcagc taggtaaagg aatccctcac ggtcaactac
    60301 atttccagct cctaccttaa ctgtatcacc atatttttca cgaatgaaat caagtgttat
    60361 tttttgccac tcagaaaaac cttctgaaga atctatacat aaaacatcag caccagcttc
    60421 aactaaagca ggaacacgtt cagcaaagtc tctggtatta ataccagctc caactacata
    60481 tctcttagaa gaatctaaaa gttcaagtgg attttcttta tgagaagagt aatctttacg
    60541 gaataccata tacataagat taccattgtc atcaagtaca ggaagagaat taagtttgtg
    60601 gtcccatata atgttgtttg cttcctttaa agtaacatct ttgttagcat aaactataga
    60661 tgacatagga gtcataaatt cactaacttt agtatctaaa tccatacgac ttatacgata
    60721 atcacgactt gcaacaatac ctaataattt accagttgaa gttccatctt cagtaacagc
    60781 tactgtagaa tgtccagttt tttcttttaa gtcaagtatg tcttttaatg tgttatcagg
    60841 tttaatattt gaatcactta caacaaaacc agctttgtgg gatttaacac gtgctaccat
    60901 agcagcttca tcttcaatag tttgagaacc gtatataaat gaaataccac cttctttagc
    60961 aagtgcaata gccattttgt catcagaaac agattgcata atagcagaag tcaaaggtat
    61021 attcatataa atatctgctt cctcgccctt tttaaattta gtaacaggtg tttttaaact
    61081 tacattagca ggtatacaat cagtagaaga gaaacctggt acaagaaggt attcactgaa
    61141 agtatgtgat ggtgtatcaa aataaaacgc cattttttaa tcactcctta tatttttata
    61201 ctttttataa ttgatagtat taattataac ttattcttta attttattaa agtattttgt
    61261 caaatattga gatttttgaa aaatttaaac tattttaatt gaatttgttt aatatatatt
    61321 gccttatagg gtaaagttgt atattaaata atgtttagtg tttaatagta gctaatttga
    61381 aattaatctt tagttattca tataattaca tttgtatagt ttatattgat aatattgcta
    61441 gagagtgcat aaacctcaaa aatacagata aattaaatct atattagtat atccaaaagt
    61501 acatttaata aatttattta actgaattat tattttcatt tctattaaat ttaaatattt
    61561 tataaaaata gtattattta caaaatcata tactccaaaa tactacataa ataaaattaa
    61621 acaaaaacta aaatgacaaa tgtcattatc taaagtgaca tagaaacggt ttcttaaagt
    61681 tgttactata aaatataaac tctataataa aagtataaca aaagggaatc atatcgatat
    61741 agaatataat tcaagaggag gtaaaattat gagtagttct aatcaatcga caataaagac
    61801 atctatacag cgagtaggga aatttttaag tggtatggta atgccaaata taggagcttt
    61861 tatagcatgg ggtcttataa cagcattatt tataccaaca ggatggatgc ctaatgaaaa
    61921 attgagtact ataggcgacc caatgataaa atacctttta ccactattga tagcttatac
    61981 tggtggtaaa gcaatagcag gacaaagagg tggcgtaata ggtgcagcag cagctatggg
    62041 agtaattgtt ggggcagata taccaatgtt tatcggagca atgataatgg gaccatttgc
    62101 aggatgggta attaagaagt tcgataaatt tgtagatgga aagataccaa caggatttga
    62161 aatgttagta aataactttt caataggtat aataggtatg cttcttgcaa tactaggatt
    62221 ttatgcaatt ggaccagcaa tagtagcagg gacagctctt atagaatctg gagttcaatt
    62281 tatagttagc aaaagtttat tgcctttagt ttcagtattt atagaacctg gaaaagtatt
    62341 attcttaaac aatgcaataa atcatggtat attagggcct ataggtatag ctgaggcaaa
    62401 agaagcaggt aaatctataa tgttcttact agaaagtaac cctggaccag gtttaggagt
    62461 tctattagca tattggatgt ttagtagagg aagtgtaaaa caatcagcac caggagctgt
    62521 aataatacat ttctttggtg gtatccatga aatttacttc ccatatattt taatgaatcc
    62581 agttttaata ttggctacaa tggcaggtgg agcagcagga atattgactt tttcaatatt
    62641 aggagctggg cttgtagcag caccatcacc aggaagtata tttgcactta tggcactagc
    62701 tccaaaggga ggattacttc cagtattagc aggggttgca gtggcaacag ttgtatcatt
    62761 cttagtggca gcaccatttg ttaagagagc ttcagcaaat gaaagtgaag aagacagtac
    62821 ttctttagaa gaagctaaag caaaaatgag tgatatgaaa tctgcaagta agaactctga
    62881 gaaaaatatt gagaaaaaac agcttgaagt aaatgagatt aagaagattg tatttgcatg
    62941 tgatgcagga atgggttcga gtgcaatggg agcttctaga tttaaaaata gaataaaaaa
    63001 cttagattta gatatagaaa ttacaaattc atctgttgat aatcttccag atgatacaca
    63061 aatagtagta actcacaata cattagttga aagagttgct aagaacaatt caagtgttga
    63121 gatagtttca ataaacaatt ttttaaatga cccaaattta gatacattat ttaaaagatt
    63181 agaatctaaa taaaaataaa aagtaccact aattaggagt ggataatttg aaaaaaaaga
    63241 agattacatc taggcaaaaa aagataatac taatgatagt agaaaattca aagaaaaaca
    63301 ttccaataac tatttctgag attgcaggga cgttagagtt aagttcaaga actgtactta
    63361 gagatatgtc tggaattgaa aaatggtttg atgaaaatga ttttaacttt gtaaaaaaac
    63421 caggagtagg attgatttta gaggaaaata tagaaaatca aaactttata attgagttgt
    63481 tagaagaaga aaaaatagaa aaagaataca gcaaggaaga aagaaattta attatattat
    63541 caaagctact agtttctaac gagccagtaa aatcttatta ttttgcaaaa atattaaagg
    63601 tatctgaagg ggtactgaat aatgattttt cattagcaag taaatggttg gaaagatttg
    63661 atattgagct tgttagaaaa ccagggcttg gtgtctacct aaaaggtcaa gaaaaaagct
    63721 ttagagaggc atatgtaaat cttatatacg attcattcaa tgaaaaagaa atactagata
    63781 tggtcagaaa tataagtgaa aatatacaaa cagataaagc aatagaaatt ttaagtgaaa
    63841 atagactttt aaatttaatg gataggtgca taataataaa agttgaagct acattaacaa
    63901 agaagctttc agatttagat gtaaatttag ctgatagtgc atatataggg cttgtagttc
    63961 atatttcatt agccttacag aggataaaaa atggtgaaaa tataactatg gataaagagt
    64021 ttctaaaaga attatctata acagaagagt ttaaattagc taaagaaatc gtaaaaggta
    64081 tggaaacaga ttttaacatg gatataccag tagatgaggt tggatatata actatgcata
    64141 taagaggtgc aaagcaaagg tcatcttcaa atcataaggc tttaaacttg gatgatatag
    64201 aaataatgga aattacaaat aagatgatag atttggctga agatgaattt aaaataagtt
    64261 taaaaaatga cgagaggtta tttaaagacc tagcaaatca cttaggacct tctataaata
    64321 gattgaatat gggattagaa ataagaaatc ctcttttaga tgaaataaaa agcaagtatt
    64381 catatgccta tgatggagtt gaaaaaattt ctagaattat aaaagataaa ctaaatataa
    64441 attcaatacc tgaatcagaa ataggatata ttgcaatgca ctttgcatca gccatagaaa
    64501 aaaatcttat gatgaatact aatataaata ttgttgtggc atgtcccact ggaataggta
    64561 cttcaagatt cttatcaact aagattgaaa ataaatttcc taatttaaat atacttgaaa
    64621 ccatatcagc tataaacata gatgaagagt atttaaaggg aaaagatgtt gatttaatag
    64681 tgtctacagt tgagttaaat acaagtttaa attatatatg tgtaggtcca tttatgagtt
    64741 tagatgatga acagataatc aaggaaaaaa taaaatctat agctcaaaat aaattaatta
    64801 atttaaatac aaaaaatgat actaaaagta agaataaagt atatgaacag ataacagaaa
    64861 gtatgaatat aggaaaagat attcttcaat ttttagagga aattagattt gaaaaatttg
    64921 aaagtaaaga tttaagtgag cttattgaag actcatcaaa aatatttgca aaatctagtg
    64981 aagatataat gtctataaaa gaatcgttaa aagaaagatt aaaaatctca attccatata
    65041 tagaagaatc aaaaattcta ttattacatt gtatgagtga aagaatagat attatgaagt
    65101 tatcaataat aaaactggag aatcgaatcg tgctagattc aaatgaagaa atcgacaatg
    65161 tagtttttat gttacttcct aaaaattcac caagttatca aagacaaata atgagtgaaa
    65221 taagtggttc attaatagac aatataattt ttactaataa gataaataaa ttctctatag
    65281 aagagatgac attagaggta aaagatatag tttttaattt ttatacaaac agattaaaag
    65341 catttataga tgaataaaat taatattaaa aaggaaggtt gatactatga gtaaagtatt
    65401 gaatgagaat aatatatttt tagggttaga tagtgtttca aaggaagaag ctataacttt
    65461 agcaggaaga aaattagttg aaaatggata tgtaaaagaa gaatatatac cagcaatgct
    65521 agaaagagaa aaagtaatga ctacatatat gggaatggga gttgctattc cacatggtgt
    65581 aaatgaagca aaaaaagaaa tattatcttc tggaatagtt atactacaat tccctaatgg
    65641 tatagatttt gatggagaaa aagcatactt attaatagga atagctggtg ttggagatga
    65701 acatttagaa atactatcta atatagcagt agttttagat gatgacttaa cagaaagact
    65761 aaaaaattca aatgacaaac aagcttttat ggaagctttt gccaaataat cttaggaggg
    65821 atttaaaatg aaaaaggcaa tccagtttgg agcaggaaat attggaagag gttttattgg
    65881 aggcttgtta gttaagtcgg gttatcatgt agtatttgct gatgtaaatg aggagatatt
    65941 aaactcaata aataaagata aaaagtatac tatacacata agagatgtag aatgtataga
    66001 tgaagtaatt gataatataa gtgcggtttc atctataaaa gaagaaataa tagatgagat
    66061 tgtacaggct gaaataataa ctacagcagt tggaccttta gttttgacta aaatagcctc
    66121 tacaattgca aaaggtataa aggctagaaa agaaaagggt ttaacaagta atctaaatat
    66181 aatagcctgt gaaaatgcaa tatacgcaag ttcttcttta aaagaagagg tacttaagta
    66241 tttaaataag gaagaagtag aatatttaga gatatatgtt ggttttccaa actgttcagt
    66301 tgatagaata gttcctcctg gtaaaaatga aaatcctctt gatgtaacag ttgaaaattt
    66361 ttatgagtgg aatgttgaaa aacaaggatt taaaggggaa ataccaacta tagttggaat
    66421 gaatttagct gacaacctta tggcttatat agagcgtaaa ttgtttacac tgaatacagg
    66481 tcatgctata acagcttata taggatattt aaaaggatat aagactatag aagagagtat
    66541 aaaagataaa tttatctgtg atatagtcaa aagtgcaatg gtagaaagtg gagaaggatt
    66601 gattaaaaaa tacaattttg actcagaagc gcactataaa tatattgata aaattttaaa
    66661 tagatttaaa aatccatatc ttaatgatga tgtattaaga gttggaaggg aaccattaag
    66721 aaaactaagt gataaagata gattgattaa acctttaatg acagcaaaat catatggatt
    66781 atcagttgac aatttgattc ttggaatagg tgcagcgctt cattataata atagtgaaga
    66841 tactcaaagt gtagaattac aagagttgat aaagtctaat ggtgtaaaaa aagctgttgc
    66901 taaaatagct aatataagca atgacgaaga acttttaaat aatatcgaaa aaagttatat
    66961 atttatgaaa aatttataaa tttacttgaa aaaaagtagt tctgataaag taactataat
    67021 atattattct acacagtttg aattatttgt tgaataatag agaattataa tatataatta
    67081 aaaggaataa attaatatat ttacctgtat atgtttgata atatggttca aatgtttcta
    67141 ctaagctacc attaatagct tgactacagg agtgaagaag atatagttta tacttatttt
    67201 aaattatata ttaagttaat tactttgaat tttaagctcc tgtctatgat atagacagga
    67261 gcttttttag tattttaata taaaatactt acaagaatag atagcaaaat tagaacaaat
    67321 ataatttttt tattaatata actttagaaa gggctaggtg gaagttcaat gaaggcttta
    67381 caagaaaaga tattgagaga aggcagtgtt tcaggaaatg atatactaaa agttgatagt
    67441 tttttaaacc atcaaattga tgtagctttt ttaaatgaaa taggaagaga atttaaagag
    67501 agatttaaag aagaaaaggt ggataagata tttacaatag aggcttcagg aatagctata
    67561 gcatcaattg tttcacagta ttttgataat gcacctgtag tatttgcaaa aaaatcagaa
    67621 tctaaaaatt tggataaaga tgtatatgag actaatgtat attcatttac taaggcaaga
    67681 gaatattcag ttaaagtttc taaaaagtac ataaacaaag gtgaaaatat attgatagtg
    67741 gatgattttt tggcaaatgg aagagctgct cttggactta aagatttaat tgagcaagca
    67801 gaagctaatt tagttggagt aggaattgtc attgaaaaag gatttcaagc tggaggagca
    67861 cttttaaagg ctaatgatgt aagattagag tctttggcgg tagttgaatc tatagataat
    67921 ggaactgtaa aatttaggta atttatgata ttatatactt gtgtttagca catattttaa
    67981 ctatgtaatt atggaggatt ttttatgata ttttttatag acacagccaa tattgaagaa
    68041 ataaaagaag caaatgattt aggtgtaata tgtggtgtaa ctactaatcc atctctaata
    68101 gctaaagaag gtagagattt tatagaggta gttaaagaaa taagtgaaat agtagatgga
    68161 ccaataagtg cagaagtaat aagtttagag catgaaggta tgatagagga agcagaaaaa
    68221 ttatctaaga tacataaaaa tatagttata aagataccta tgacagcaga aggtctaaaa
    68281 gcggtgaaag tactatcaag taaaggtata aaaactaatg taacacttat attctctgct
    68341 ggacaagctc ttttagctgc tagagctgga gctacatatg taagtccttt tgttggtaga
    68401 ttggatgata tatcacaaaa tggtcttgat ttaattgaag aaatcgttga tatatttagt
    68461 gtaaatagta ttgaggctca aataatagtt gctagtgtta gaaatccaat acatgtttta
    68521 caagctgcta gaatgggagc agatatagca acagttcctc ttaaagttat aaaccaaatg
    68581 attaagcatc ctttgacaga caaaggaata gatagcttta tgaaggattg ggaaggtgct
    68641 tctttaaaat tataattata aactacgctt tataagtata ttaaagaggt tattatggaa
    68701 attctaagta ataaggctag gctattttgc ctagtcttat tttggtgtat aatatattga
    68761 aacatattat tgaaatagat taatttttta agtgaggagg cgaaaaatgg ataaaatatt
    68821 aagagagata caaagagaag ataaaaaaaa tccatatact gaccaagaac ttgctgaaat
    68881 gttaaatgta gctaggtctg aagtgatatc agtgaggaaa aaaaataata ttttagattc
    68941 gagagaaaga agaaaaaaaa tattaataaa agatatatca aaaattgtaa gtgaaaatcc
    69001 tcaaatgtct gaaagaaaaa taactgagat attaatagag aatggatata atatatcgag
    69061 aagtgcagtt tcaaaattat taaaagaaga aaatttaaat cagtcaaaga ttgggattaa
    69121 agataaagag ccagcatcat caggaaagta tgtgaaggtg agtaaagttg tagaagaaga
    69181 tggatttgaa gaattgatag gtataaaggg aagtttgaaa gaaaaggtaa atctagctaa
    69241 gtcagcaata atgtatcctc ctaatggcct tcatactata atatatggag aaacaggggt
    69301 aggtaaaagt gaattagcta catgtatgta taaatatgct ataaaaaaca acatcaaaga
    69361 agagaacagc ccatttatag tgtttaactg tgcagactat gcagaaaatc ctaatctatt
    69421 gatagctcaa ctctttgggg tagtaaaagg tgcatataca ggagctgatg caaatagaga
    69481 aggtcttgta gaacaagcta ataatggaat attgttttta gatgaaattc atagattgcc
    69541 tgctgctggg caagaaatct tattttcatt aatagataga ggagaattta gaaggttagg
    69601 agaaagtagt tctaatagaa aggcaaatgt tctcataata agtgctacaa cagaaaaccc
    69661 agattctaat ttacttcaaa catttagaag acgtatacca atggtaataa atttacctaa
    69721 tatgagtgaa agaccaaaat ctgaaagata tgaaataata ataaagtttt ttgaaagaga
    69781 agcaaagcga gtaaacaaga attttataat aactaaagaa gttatgtgtg cacttatgaa
    69841 ttataagtgt actggaaata taggtcagtt aaagagtgat atacaagtaa cttgtgctag
    69901 agcttttagt aaatcaatat tttctagcga taaggtaatt atagatttag atagtttaag
    69961 ggattatata aaaagtggat attatgattg taattgtaaa aatgaaaagt attctgagtt
    70021 ttcagttgag gatatatata tagatatcag tgaattggtg agtggaaaaa atagaatttt
    70081 atctgataat gagataagcg agatatataa ttatgcagaa aaagagctta aggttttgga
    70141 aagtaagtgt ttttcagaag aagagttaaa aaatgcattt atagaaaagt tagataagaa
    70201 gtttaatgct attaaaaaca ataaaaattt atctgataga agaagtcgaa tagactgggg
    70261 aggacaatta aaagagtcta cattggagat aatggataag gtaattgtat ttattaagga
    70321 gcagtttaag catgtaaatc aaggattgta cttggctcta gcaattcaca ttgagcatgc
    70381 tataggtagg ataaaagatg gaaaaactat aataaatccg agtttagata aaataaaagc
    70441 atcaatgcca atggaatatg aattgtcaag atatataatg ggtatagtgg aagatttgac
    70501 acaagtaaca tttccagaag atgaacttgg atatttggct tattatataa ataaattttg
    70561 ttataatgag gaaagtataa aagataaagt taaagtagta atagttacgc atggtaaagt
    70621 tggaattgaa atgtctaaag ttgtaaatca tattttaggt atagaatgta cactaggtat
    70681 agaaatagca cttacagatt caccatcaga ggggatagag catgtattag aagagcttca
    70741 aaagatagaa gctagaaaag gtattctagt tctaattgat atgggttctt tggtaattct
    70801 tggtgatgag gttgaaaaaa gacttggaat tagatgtaaa actgtaaaca gagtagatac
    70861 gttattggca atggaagcag gaaaacttgc aaccattgaa ggaaaaagtt tagatggtat
    70921 aatagcagat ttaaagaaaa ataagaatta tgccatgata aatacaaata aatttagtta
    70981 cagaaaaaac gagtatggaa agaaaaatgt aatcattact ttatgtttga gtggtgtagg
    71041 tacagcttta aatttaaaag agcatataga aaaacaaatt aaggaatatg acactttaat
    71101 tgaggtaaag ccagttgctt ttttaaataa taatttagaa gaagagttaa atgatattga
    71161 agctgaatat aatattattg ctatctgtgg aactatcgat atagattata aaaacgtacc
    71221 ttttatttct tataatgagg tacttggtaa aaatggtatt aataaagtat tagagcattt
    71281 aaacagtaaa caaccagttt taaatattga aaaccagttg aataatttaa tacatgaaga
    71341 tttgatttta tacaattttg aaggaatttc aaaggagtat ataattgata ctcttgtttc
    71401 aaagcttgaa gaaggtggat atgttgactc aaagtatata ttaagtgtat ataaaagaga
    71461 agcaatggga agtgttgtaa tggcctctaa ggtagccgtg ccacatggac ttccagaaaa
    71521 cgttataaag cctgcaatag caatcgcaag gttgaataag cctatagtgt gggacaataa
    71581 atttatggtg gatttggtag tactactggc acttaaagaa aataataaga aagaaatacg
    71641 aagcttattt tcaaagatta atgaccaaca tactttagaa gttttattaa atactgaaga
    71701 taaaaatgaa ataaaagaac ttttaagcta attattagta cagagaagaa agacaaaaaa
    71761 tttgctttag tataaaattt aaaactactt aattgctaag tagttaatta ctcgatataa
    71821 ggctagttct atgaaattta tttatatgat tttatagaat tagctttttt cttggtaaat
    71881 aaaatatatg aatttattta tgcaaaaagt aaattttatt ggacaattct atgagaattt
    71941 ttcctatatt tcttataaaa tatagaatat ataaaaataa attaaattca taataaataa
    72001 ttttataaaa tagttgttaa acataaaaaa ccatttgtaa aaaacaaaaa aatcatttct
    72061 ctaacaaaaa aaaccacaaa aaatataaaa aagtatggct agttaagtga ttaacaagta
    72121 aaaattaaaa taaaaatcaa aaaaaattta tcaatgaaag tcagctaaaa tcctggaaga
    72181 gagcattatt tttgggaaaa cattttcttt tgtttcacaa aaaaagccac tttttggcac
    72241 acaacatgct ttatataaag tcaagaaaaa ctaaggtata agacaaaggc aattaggagg
    72301 tgtaaatatg gagtttataa attttgtaag tgataaagtt atagacctta aaatggattg
    72361 taaaacgaaa gaagatttct ttaaagaaat acataataaa gtttttgatt taggctttgt
    72421 aaaagaagaa tttggagaaa aaatattagc aagagaaaat gtatttccaa caggtttaaa
    72481 tttaggagat tatggagtag caataccaca tacagatgca gaatatatta aagagcaatt
    72541 tatatcagtc tgtactttta atgaaccagt agtgtttagt tctatggaag accaagatga
    72601 aaaagtacct gtaaatttgg ctttcgtatt aggacttaat caaccacaca gtcaattatc
    72661 tgtattaaca gaattaatgg gaattatgca aaataaagag ttagttgata agttgatgag
    72721 ttctactgat aaagaagaag ttttaaagac actaaagtct ttataaaaat aaaaaagtac
    72781 taaaaataaa aaatataaaa ataaaaatta ttaggaggaa ataaaaatga aaaaaatatt
    72841 agtagcatgt ggagcaggaa tagcaacatc aacagtagtt tgtgacaagg tagagagatt
    72901 agttaaggaa aataatatac aagcagaagt tatacaatgc aaaatagctg aatgtgcaac
    72961 aaagcaagaa ggagcagatt taatagtatc aacaactata ctaccaacaa cttataatat
    73021 accagcaata aaagcaacag catatataac tggagtaaat acagcagcat tagataaaaa
    73081 aatattagat gctttaaaat aatcctatca tagatacatt gaaataatat tttataaaac
    73141 agaaaaagga ggatttataa atggataaat tattagcagt agtacaatac attttaaata
    73201 tgggaccgac agtaatacta ccaataacaa ttgtagtact aggaatgata tttagaatta
    73261 agtttacaaa agctttaaag tcaggtctta caattggtat aggatttgtg ggtataaact
    73321 tagttgtaaa cctattaaca tcaacactag ggccagcggc tcaaggaatg gttgaaagat
    73381 tcggacttaa tttaacagta atagatgttg gttggccaac aacagcatca gcaacatggg
    73441 cttcaccagt tgcaccaata ttaataccag tttgtttatt agtaaactta ctattattat
    73501 acttcaataa aacaaagata ttaaacgttg atatatggaa ttattggcac tttatagtag
    73561 caggtgcagt tggatatata gtaacaggaa gttatgtttg ggctatattc tgtgcaatac
    73621 taatggagtt attagtactg tttattgcag aaaagacagc aaaaaatgtt caggagtttt
    73681 atgatttaga aggtatagca ttaccaactg gttcaacagc ttcatttgct ccacttggat
    73741 atttagtagg taaatttgtt gaaaaaatac caggaataaa taaaatacaa gcagacccag
    73801 actctataca aaaaagattt ggtatatttg gagaaccaat gatgatgggg attatactag
    73861 gtataatact tggagcactt gcgggatatg atgtagcagg aatattcaat gtaggtatat
    73921 caatgggtgc agtaatgtta cttatgccta gaatggttag aatattaatg gaaggtttaa
    73981 ttccaatttc agaatcaata agagatttct tacaagcaaa atatggagac agagaacttt
    74041 atataggtct ggatgcagca gtagcaactg gacatccagc agttatatca acagctctta
    74101 tacttgttcc tataactttg ttcttagcag ttatactacc aggaaacaaa gttttaccat
    74161 ttggagactt agcgacaata ccattttata tggcatttat agtgtgtttt agaaaaggta
    74221 atatagttca atcagttata acaggaacaa tagtaatagc tatatcactt tatatggcta
    74281 caaactttgc agatgttcat acacaattat tacaacaagc aaatatgatg ccagaaggaa
    74341 caacaatggt tacaagtata gatacaggtg gaaacttgct aaaatgggga atattgaaat
    74401 tatctcaatt agtttcttca tttggaatat tctagtatgt agttaataga gattactctt
    74461 ttttagtaaa gtatgcgaaa atttaacatt tagcagctac taaaaaagag taatattttt
    74521 tataaatttt taaaaataca aaatacaaga ggaggagatt tatcgtgaaa gcagcagtat
    74581 tacatggcac aaatgatatg agatttgaag atatagaaat aaaaccatgt gaaagtgatg
    74641 aagtaaaaat aaaagttatg gcagcaggaa tatgtgggtc agatcctcca agagtattaa
    74701 aacattggaa atatccagtt ccagctatac caggacatga gttttctgga gtaattgctg
    74761 aagttggtaa ggatgtaaaa aatgtaaaag ttggagatag agtagttgca attcctttta
    74821 taccttgtaa tgaatgtgaa tattgtaaaa gaggattatt ttcattgtgt gatgaccatg
    74881 gaatgttagg agctaaaagt tttggagctt ttgcagagta tgtaaatata aaagctacaa
    74941 atgtacttcc aataggagat atgaactttg aagatgctgc aatgatagag ccactagcag
    75001 ttgctatgca tggagtactt aatataggtg ttcaagttgg agacactgta gctgtaatgg
    75061 gtagtggaac aatggggcag ttggtaatac aaggacttaa aatagcaggg gcaggaacaa
    75121 ttatagcagt tgatatatct gataataaat taagagaatc aaaggaatta ggggctgata
    75181 taataattaa tgctaaagat attaacccag tagaaaaaat aaaagaactt actggtggaa
    75241 aaggtgttga catagctctt gaatgtgcag gttcaaaaat aactcaagaa caatgtttac
    75301 ttataactaa aaagaaaagt aagataggat ttttagggat agcatattca gatataactt
    75361 tatcagaaga agcatttgaa aatatattta gaaaagaact agaattaaaa ggtttttgga
    75421 actcttattc tgcaccattt ccaggacaag aatggactaa gggaatcaat ctagttaatg
    75481 aaggaaagat aaaattaaaa gaaatggtat ctcatagatt ctcacttgaa gatacttaca
    75541 aagcatttga aatgataaga gatagaaaag aagaatttaa caaaatatta attttaccac
    75601 aaggggttga aaaataatga aagcagtagt taaaactaaa ccaggctatg ataatgtaga
    75661 agttttagaa gtagaagaac caaaagctac aggagacaag gttaaaataa aagtagaata
    75721 tagtggtata tgtggttcag atatacattc atttaaaggt gaatatgcaa atataaaagc
    75781 cccagtaaca ttaggtcatg aattttctgg aattgttgta gaagtaggag aagatgttaa
    75841 aaatataaaa gtaggggata gagttacatc agagactact tttgcaactt gtgagaaatg
    75901 tatatattgt gaaactaaag attataactt atgcccaact agaaaaggta ttggtactca
    75961 agtaaatgga agttttgctg agtatgtatt atcaagagaa gaaagcatac atgtacttcc
    76021 tgaaaatgta tctttattat cagcagccct tacagagcca ctagcttgtt gtgttcatgc
    76081 agctcttgaa aagactacta tagaaagttc tgatacagtt ttaataatag gaccaggacc
    76141 aattggttta ttattagctc aagttgttaa atctcaaggt gctacagtta taatgtctgg
    76201 tgttacaaaa gataaggaaa gattagaaat agctaaaaat cttggagtag atagaactgt
    76261 aaatgtaatg gaagaaagtt tggcagatgt agtgaatgaa atgactgatg gaaatggagt
    76321 aaacaaagga tttgattgtt ctgggtttat gccagcagtt aacgaagcct taagactgct
    76381 tagaaaaaaa ggtactttcg tacaagttgg aatctttgct aaaaaattaa atgaaatgga
    76441 ccaagaagca ataatccaaa gagagttaca atatatagga agcaggtctc aaaagccaag
    76501 ttcttggatt acagcattag atttaatggc aaatgggaaa gtaaatacag aagctttagt
    76561 tactagaact gttggtttag acgaatttaa agaaggtatt acagctttaa tgaacgggga
    76621 agaaataaaa gtagcagtaa aatcttaaaa aaacatttgt attattttaa aaaaaattgt
    76681 aaaatctact gtaggataaa aaaatgtaag gtcttaaaaa ataacaggag gaagaaagta
    76741 tgagcactct tagagatcat tctaataata ttagaaaaaa cataataaaa atggttgcag
    76801 aagctaaaag cggacatcca ggtggttcat tatcaatagc tgatatgttg acagtattat
    76861 attttgataa gatgaacgta tgtgcagaaa atccaaaaat ggctgataga gatagatttg
    76921 ttctatcaaa aggtcatgca gcaccagctt tatatgctac attagcagaa aaaggatttt
    76981 tcccagaaga agaattaata acactaagaa aatttggttc taagttacaa ggtcacccag
    77041 acatgaaaaa agtagcagga atcgatatgt ctactggttc tcttggtcaa gggctatctg
    77101 cagcaaatgg tatggcactt gcaggaaaat tagataacaa agactataca gtatatacta
    77161 tattaggtga tggagaaatc caagaaggtc aaatatggga agctgcaatg acagcatcac
    77221 attacaaatt agataattta attgcatttg ttgacttaaa tggattacaa atagatggtt
    77281 ctaatgaaga agtaatgaat gtaagtccag tagatgacaa attcaaatct tttggatgga
    77341 atgtaatagt aataaatgga cattcttttg aagaaatagg aaatgcagtt gatgaagcta
    77401 aaaaagttac aggaaaacca actgtaataa tagctaaaac agtaaaaggt aaaggtgttt
    77461 catttatgga aaataatgct gcatggcatg gaacagctcc aaatgcagaa caagcagagc
    77521 aagcattgaa agatttagaa ggaggtctat aggaatggga atagcaacta gagaagctta
    77581 cggacaagtg ttaaaagaac ttgcagaaaa taaagatata gtagtattag atgcagattt
    77641 aggaaaagct acaaaaagta tatcatttaa agaagttgcc ccagatagat tttttgacat
    77701 ggggatagca gaaggtgaca tgattggtac agcagcaggt cttgctactt gtggaaaaat
    77761 accttttgcg agtacttttg caatatttgc agcaggaaga ggctatgagc aaataagaaa
    77821 ctctgtagca tatccaaatt taaatgtaaa aatagcagct actcatgcag gtgtaacagt
    77881 aggtgaagat ggtggtagcc atcaagctat agaggatata tctctaatga gaggtatacc
    77941 aaatatggtt gtattaaatc cagcagatgc tttagaagca agacaagcta ttcttacatc
    78001 tattgattat aatggacctg tttatataag attaggtaga gctgcaactc ctgatgtaaa
    78061 cagtgaaaat tataaatttg aaataggaaa aggaactgtt ttaagagaag gttctgacat
    78121 aacagtaata gctacaggaa taatggtagc aaaagcctta gaagcagcag aagaacttgc
    78181 taaagaaggt ataaatgtag aagttgttaa tatatctaca ataaaaccat tagatgaagc
    78241 attaataaaa gaaactgcta agaaaactgg aaaagtagtt acagcagagg agcacagtat
    78301 aataggtggt ttaggttcag ctgtatgtga agctttagca gaaactaaag atgtagtagt
    78361 tagaagaatt ggtgttaaag atgtatttgg tcaatcaggt acaccagctg atttattaaa
    78421 acactatggt ttaactacag aagatatagt aaaaaatata aaagagttgt tatagatata
    78481 aatatatcta aataacaaat tgatttgaca taagtcaatt aaagctgtct taaaaataga
    78541 aagaaatttc tacaatggga cagctttatt tttacaatac tttattttta tgataattat
    78601 aaaatagtct gaaagtaatc aaaaaaatta taaaaagagg tgctatttaa tgaaaatatc
    78661 tattggatgt gaccatggtg gttatgaatt aaaggaatat ataaaggaaa atttaataaa
    78721 taaaggtata gaagttgaag atgtgggtac aaattcaaaa gaaagtgtag attttccaat
    78781 atatgcaaaa aaggtaagtc aaaatgttca aagtaaaaaa tctgatttag gcatactttg
    78841 ttgtggaaca ggaataggta tgtctattgc agcaaataag tttaaaggaa tcagagcagc
    78901 tgttgtttct gactgttttt cagctaaggc aactagagaa cacaataata caaatgtact
    78961 ttgtttagga gaaagagtta ttgggaaagg attagcaatg agaattgttg aagaatggtt
    79021 aaattcaagt tataatggag aaagacatgc aagaagatta caaatgattg atgatataga
    79081 aaaagaaaat ttataaatat ataatttaca acaaggggga gcgttatgtc tattatttgt
    79141 gcttcaataa tgtgtgcaga ccaaatgaag ttaaaagagg aattagaagc tcttgaagaa
    79201 gcaggtgtaa aattacttca ttgtgatgtt atggatggaa tatttgttaa aaacttggct
    79261 atgggaccag agttattaaa atcaataagt gaaaatacaa caataccttt agacatacac
    79321 ttagccacag aaactccaga taaatatatt gatatgatgt cttatataaa gccaaaatat
    79381 atttcttttc atgtagaatc aagtacaaat gtaaaagctg atatacaaaa gttaagaaat
    79441 tatggtatag ggccagtgtt agcaataagc cctcaaacaa gtgtggataa aatagaagaa
    79501 tatataagtt tagttgaggg tatcttagta atgacagtaa atccagggtt tgcaggtcaa
    79561 aagtttaatc tttctgtatt ggataagttg gataaactta cagagatact aaaagattat
    79621 gataatcctc catttataga ggttgatgga aatataaata aggatactat taaacttatg
    79681 aatggtaaaa aagtagatat atatgttgtt ggtacttcag ctttatttaa tgataagcct
    79741 ccaatttcat ataaagataa aatagaagaa ctaaaagaaa gtataaagta accatgtaat
    79801 aaaattataa tatgtttctg tttaatagta aaaatttagg tggaaacaag aaattttata
    79861 atatttaata aaaattttgg ttgagtaagg agaatttttt atgggagacc tatataaact
    79921 acaaaatggt actgatatta gaggaatagc gtatgaaaat gattctaaag aagttaacct
    79981 aactgtagaa gaagtaaaaa aaatagctaa agcgtttcat atttggttaa aagaaaagac
    80041 taagaaagat aaagtaactg ttgccatagg aactgattct aggataacag gaagccaatt
    80101 tagaagtact gttattgaaa ctttaactaa tgatgattgt aatgtaattg attgtgagat
    80161 tgccacaact ccagctatgt ttatgacaac tattatggat ggatacaatt ctgatggggc
    80221 gattatgatt acagcaagtc acttacctta ttactataat ggtttaaagt ttttcacaga
    80281 aagtggaggt ttagaaaaaa ctgatataaa agagatgttg gatatagctg ttaaaaatga
    80341 tagtgtagac tatgaggaag taaataaaaa aggtgaagtt atagtaaaaa atttaataga
    80401 agattattct aatttattga tagataaaat tagaaaaggt gtaaattcaa gtaaaaatta
    80461 tgaaaagcct ttttctgggc ttaagatatt ggttgatgca ggaaatgggg ctggtggatt
    80521 ctttgctgaa aaagttttac acatactggg agcagatacg acaggtagtc agtttttgaa
    80581 cccagatggt atgttcccaa atcatatacc taatcccgaa aacaaagaag caatggaaag
    80641 catatgtaaa gctgtgttgg ataataagag cgacctagga ataatctttg atacagatgt
    80701 agacagagct gctattgtag gtaaaaatgg caaaccaata aataaaaatg ctcttatagc
    80761 tgttatatca tcaatagtat tagaagaaca tccaaaaaca gctatagtaa cagattcgat
    80821 tacttctgaa ggacttgcta aatttataaa tgaattacaa ggaagacatc atagatttaa
    80881 aagaggatat aaaaatgtaa taaatgaagc tataagatta aatagtgaag gtgaagagtg
    80941 ccatttagct atagaaacgt ctggacatgc tgctttaaaa gaaaattatt tcttagatga
    81001 tggggcatat ttaatagcta aaattttaat aaaagtagca aagctatcct tggaaggaaa
    81061 gactatagaa gaattgatag aaaaccttga agaagctcaa gaagagaaag aagttagaat
    81121 aggcattaat aaagaagatt ttagaacata tgcagaggat atattaaaag atttagattc
    81181 tcatgttaag agtattgatg gatggtctgt agcaccaaat aattttgaag gcataagagt
    81241 taattgtgat gaatcaaatg gagatggatg gtttttactt agaatatcac tacatgaacc
    81301 attattagct ttaaatattg aatcaaataa aattggcgga gcagaacaaa tttattctaa
    81361 gttaaaactt ttcttagaaa aatatgattt aaaaggtctt tagggtaaat agaaagaata
    81421 tatttatatt gaagaataaa tgtaaatttg tacctaagat tacaaatatt acaaaattgt
    81481 aatcttaggt aacagagatg taactgatta tggaaacact atgtgatatt atagatacag
    81541 agagatgaaa tatgtgatga attatagaga aatataattt aaaatgtatt aatatcacac
    81601 caaaaaggta taatcaaaaa atatgtaaat ataaacccca acatttagaa aaagacctct
    81661 aaggaggttt ttttcttgtt taaataactt aaaatatatt tttatattaa tatatcaatt
    81721 aacttttcta aaagtaagca ttaccttaaa taaatcagca tctataatta tttccatgtg
    81781 tgcattttct aattcaatta tattttgagc aattgataaa ccaagaccag agccatctgt
    81841 ttttctagat atatcacccc ttctaaatct ttctattaac tcttctggtt ttagatttag
    81901 tttatcattt gaaatatttt taaacgttaa tattatattt tcttccttta taaacatatc
    81961 tatatagacc ctagtgttag gcatagagta ttttagtata ttgcaaatta gattctcaaa
    82021 aactctccaa gtttttttac catctatcat ggtaaaaaca gcatattcag gtgtttctat
    82081 tataaaatct aaactgctat tttgaatttt gtcttcaaat tctacaatac tttgaattaa
    82141 aagttctctt atatcggttt ttgttatatt aaattctaca tctccactac ttagcttaga
    82201 tgcttcaaat atgtcatcta ttaataattt taatctttgt gattttttat ctaaaatatt
    82261 tatatagtca tttatagtct ctctgtcaaa gtcattattt tttaacatat caacatagct
    82321 taatatagat gtaagtggag tttttaagtc atgagatacg tttgtgataa gctctgcctt
    82381 catcctttca ttttttatat tagcatctac agcagtttca agaccgcctg ttatattatt
    82441 tatacttttg gctaaagtag atatttcatc atctcctata acttctaatt tatactttaa
    82501 attgccattt tctatatttt ttatattttt tgatatgtta tttatgtaat taaacttaac
    82561 agataaaaag ttgtatatat aaaaatgaaa aactgtgttt acaagtgtaa ataaaattac
    82621 tatagctatt gcctcagcat aatatatata cataaagaat atcaaaacaa gatattggat
    82681 aatagcttgt acaactatag atattaaaaa tactatagct aattttttat ttatagtttt
    82741 tttattatac atactaag
//
LOCUS       DAEPHU010000005        82497 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 01A10CD0081
            SAMN05941466-rid12468953.denovo.005, whole genome shotgun sequence.
ACCESSION   DAEPHU010000005 DAEPHU010000000
VERSION     DAEPHU010000005.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941466
            Sequence Read Archive: SRR6291087
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 82497)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 82497)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068158.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 22:43:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,892
            CDSs (total)                      :: 3,805
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 87
            rRNAs                             :: 8, 1, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 55
            CDSs (without protein)            :: 55
            Pseudo Genes (ambiguous residues) :: 0 of 55
            Pseudo Genes (frameshifted)       :: 21 of 55
            Pseudo Genes (incomplete)         :: 28 of 55
            Pseudo Genes (internal stop)      :: 16 of 55
            Pseudo Genes (multiple problems)  :: 8 of 55
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..82497
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941466-rid12468953.denovo.005"
                     /strain="01A10CD0081"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            530..1801
                     /gene="serS"
                     /locus_tag="KR231_000370"
     CDS             530..1801
                     /gene="serS"
                     /locus_tag="KR231_000370"
                     /EC_number="6.1.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000884181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine--tRNA ligase"
                     /protein_id="HBH0002788.1"
                     /translation="MLDIKRIRENLDCIKKAMERRGEKNFNLDEVVKLDDERRKTLQE
                     VEVMKNELNTASKNIPNLIKEGKDVENEKIKLKELSDKIKVIDQNLKEVEDKMEYLLM
                     RIPNVPHPEVPQGETDEDNVEVRTWGKTTTFDFESKAHWEIGTELGILDFETASKITG
                     SRFTLYKGLGARLERALLNFYLDTNTKVNGYTEVIPPFMANRNSFLGTGQLPKFEEDM
                     FKIEGMDYFMIPTSEVPLTNIHANEILKFEQLPINYTAYTPCFRSEAGSAGRDTRGLV
                     RQHQFNKVEMVKIVAPEESYNELEKLTNNAETMLQLLNLPYRVVKICTGDLGFTASFK
                     YDVEVWMPSYNRYVEISSCSNCEDFQARRAGIRFKRDKDSKAEYVHTLNGSGLAIGRS
                     VAAILENYQQEDGSVVVPEVLRPYMGVSVIK"
     gene            2169..3674
                     /locus_tag="KR231_000371"
     CDS             2169..3674
                     /locus_tag="KR231_000371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine kinase"
                     /protein_id="HBH0002789.1"
                     /translation="MKIQNTEWGYIEWKHTYDENNPKQAMNIYIAVTMPGKKHFNHVH
                     YGQEQMIYILEGEGLYIINGVWKPFYQGMIFYIESGSTHETINTGDREIKELIVSNNV
                     DDVGESEVIDINPNNYLKKTLINYSESTLNLYAAVESIRGQFIDPFKIPLIIYDDSWN
                     IVLKNPYFPLFCFEKCNPMKFPQNCDCMNQKSSNQFVCEYGITIYNIPILYKSNSIGV
                     IRGGYVLLSDLNLDTEHNNLYDIPEGAARSIKRLLKQISKNIINFCSFNDIRKDLQEK
                     EKTIARTYHYGEQLEMNLKVAQDMVTNLRINHHFLFNTLNSMASIALDDGSYDLYSAI
                     IDLSRMFRYTMRSDLRFVELESEILYIKNYLNLQKLRYGDALKVKYLIPEKLYNLSVP
                     FNFIQPIVENAFTHGFRDIDTEKRIEIIARLDSQYAIIEIHNNGTILDGNNIDKIKAG
                     IRSNNGHGLSLIYTKFTSAYGNNFDMDIKSSDNEGTYIMIKIPIENYKEYV"
     gene            3788..4486
                     /locus_tag="KR231_000372"
     CDS             3788..4486
                     /locus_tag="KR231_000372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HBH0002790.1"
                     /translation="MRRALIIDDEEAVLKIITHFIEMKDMPIKIVGKATSGDEAVDKI
                     IGLEPDIVFIDIQMPIYNGLEVIEKTSHLSKKINFVVITAFNYFEYAQKALRLNVKDI
                     LLKPLDMKEFTKSVEKIIGYQYTNNDLLNEILEYINLNYSNDLKLNDCARLFLTNPSN
                     ISRIFKSNLNTTFISYLNHIRIEKSIELLENTTKSINEIAEIVGYNSLNNFYKNFKIE
                     KGMTPKVYKLNTKN"
     gene            4771..5859
                     /locus_tag="KR231_000373"
     CDS             4771..5859
                     /locus_tag="KR231_000373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0002791.1"
                     /translation="MSDKVNMKNIICIAGAYLATAIGSGFATGQEILQFFASQGYMGL
                     IGALISMVLFSFLGAEVITRGRELKLKEPTRIYTFYCGKILGKFYEWFSPIFLFGILI
                     VMISGAGSTLTEYYGINPYLGRVLMAVATLITVSMGLEKLVSILGRIGPVIAVFTIAV
                     GLISLFKHFDGLSMVGEAMKNIEVTKASESPIVSGVIYNTLNIIVMIVFLTGMGASIE
                     SKKDAFWGGLLGGIVFMTAGIVMYLAMISDIGNLYMKEIPSLYLADNISPIVGVCFSV
                     ALILGIYTTAVPLLWSVTNRIVEDEHPKFKLVTTVIAILACIGGFLPFGKLVNILYPY
                     TGYMGLLILVCMVYKAITCRKKSTQSQE"
     gene            6098..7288
                     /locus_tag="KR231_000374"
     CDS             6098..7288
                     /locus_tag="KR231_000374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HBH0002792.1"
                     /translation="MHELILISEKYKEDILDFFTDIHMHPELSFKEFRTTKAIKDLLV
                     SLDIEILDLGMETGVVGLLKGKYDGPTVALRGDIDALPIYEEVDIKYKSRYDGIMHAC
                     GHDIHTSCLVGCAYVLSHIRDSLHGNVKFIFQPAEEVNKGAKMLVERGVMENPKVDAI
                     FGLHNHPDIPCGKIGVKLGGLMAAVDTIKIEVNGFGGHGGIPNRTIDPIVASSAIIMG
                     IQTIVSRNISPLESAVISIGTINGGTANNVISEKVDMTGTCRSFSNEVRKKISENLEN
                     IVCEIARGYQATAKLDYLFDLPAVINSKEMYAIACKSVCDLYSEDAIVDPIPSTGGED
                     FSIFMEKAPGFFYWLGVGNKEQDCIYQWHNPKFKADKNSILVGTNVLCQSVINYMDKL
                     KNKI"
     gene            7379..8881
                     /locus_tag="KR231_000375"
     CDS             7379..8881
                     /locus_tag="KR231_000375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbgT family transporter"
                     /protein_id="HBH0002793.1"
                     /translation="MRALNVVERAGNKLPDPVTIFLLLCIIVVILSAVISNLGVEEIH
                     PSTKEVVKVVNLLEKEQIQSYLGSIVTNFQSFAPLGLVLVTMLGAGVAEKSGFMEVLM
                     KKGISKVPQKLVTVAIVFAGMLSHTAADVGFIILPPLAALVFLGIGRHPLVGMFAAFA
                     GVAGGFAANVMLSTTDVLLAGFTIPAAQMMDPSYQGNPAMNLYFAFISAIVLTFAGAF
                     VTEKFIAPRFTKYNDSTNDKDIQELSELENKGIKYALLSLLVVVVVIVALCIGDNAFM
                     KDPETGSILSSNAPLMKGIVPIITIIFLTPGLVYGKVSKKIKSDKDLVSMMGSSMSDM
                     GGYIVLAFIASQFINLFNLSNLGTILSITGAKLLAESGIPSYGLIIGFILLSGFINLF
                     VGSASAKWAILAPIFVPMFMLLDFNPALTQIAYRIGDASTNPISPLFPYFPVILAFAR
                     RYDKDIGIGTVISNMIPYSVVFTLIEIIILLLFMGIGIPLGPGGGISYVL"
     gene            8953..10209
                     /locus_tag="KR231_000376"
     CDS             8953..10209
                     /locus_tag="KR231_000376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydroxymethyltransferase"
                     /protein_id="HBH0002794.1"
                     /translation="MLKTTKISDPELYKIVADELVRQEHNIEMIASESTAPTEVLELS
                     GCVFTNKTEEGYPGARFQAGSEEADKLETLAIKRAKEVFGAEHVNVQPYSGSTANYCV
                     YSSILKPNDTVLSMRLDQGGHLTHGSAVNFLHDIYKYEFYGVDPNTGRIDYDALEAKA
                     KECRPKLIIAGASSYPRLIDYERISKVAKEVGAYFMVDMAHVAGLVAAKVIPSPVPYA
                     DFVSSSTTKTFCGPRSGIVLCKAEHAKKLDKGVFPGTLGSIHLNTVAAKAFSLLYLST
                     DKFKKIMEQVVVNAQTLASELISHGFSIVSGGTDNHIVMVDLRSKNLTGKQFEKALEY
                     VGITVNKNVIPDDPQSPFVTSGVRIGLTSISQRGLKEKEVIQIAGIMNKVAENIDNKE
                     VLDECKAEAQELISKFPLYPEGYFED"
     gene            10381..13155
                     /locus_tag="KR231_000377"
     CDS             10381..13155
                     /locus_tag="KR231_000377"
                     /EC_number="7.2.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="calcium-translocating P-type ATPase, PMCA-type"
                     /protein_id="HBH0002795.1"
                     /translation="MRYYNKPTKEVLKYLKTNPEIGLDDNEVEERKLRYGLNEFTIKE
                     GRTFWDELGESLTEPMILILIGAAVISSFVGELHDALGILGAIFIGISIGIITEGKSK
                     KAAHALSKLTENIEVKVLRNGKIIKISKNDLVPGDIVYIETGDMIPADGRLIQSINLK
                     LREDMLTGESDDVAKNADAVLDMEVVYSKTEIIEQDAIPAKQVNMVFGGTLVAYGRGI
                     MVVTHTGDKTEMGKIAQNLSNEDQQTPLQIKLGKLGAKIAGISGVIATLLCMFMIIQM
                     QRKGMLILDTSSVLSFLQSLEPAKNAYMVCIALIVATVPEGLPTMINITLAITMQKMA
                     KINALVTKKEACETIGSVSVICSDKTGTLTQNKMMVEVAYVDGKYISGGEYQSNSYFE
                     QNCIVNSTADIEKEDNSFKYIGSATECALLLYHNDKNYNEMRKQTYLISQIPFSSEEK
                     KMSTLIRQEDSDILLSKGAPEVLLKKCSYVQQGKNIVPITPKVEKSILDEIKKLQIKS
                     MRTLGFAYKKMSNSKTEVAMTSEGELNLIGNSRSYMKEDNLVFSGFVGIVDPLREGVK
                     DSIDKAFNAGVDVKMLTGDNINTATAIGNELGLLNDGKKAVEATYIDVLTDKELREEI
                     KGISIVARSKPDTKMRIVSALQKSGEVVAVTGDGINDAPALSQADVGIAMGISGTEVS
                     KNAADIILTDDSFSTIVEGIKWGRGIYENFQRFIQFQLTVNIVAFIIAIISQLTGKDM
                     PFTTIQLLWVNIIMDGPPALALGLEPVRDYVLKRKPINRHSGIIARSMFVNIIINAIL
                     IITIVFTQSAFNILGATSEEQGTVIFSLFAFSALFNALNCREFGLNSTIPNFFKNKLA
                     LQIIVVTGIIQIIFTQVFQSFFNSVSLDFDMWIKIILFASTILLSNEFVKLILRTMKN
                     SRTMNFNSKN"
     gene            complement(13256..13405)
                     /locus_tag="KR231_000378"
     CDS             complement(13256..13405)
                     /locus_tag="KR231_000378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proline--tRNA ligase"
                     /protein_id="HBH0002796.1"
                     /translation="MFFISYIYTKSPIEFDTPLQKEAYKILQKLDIDFECVDTDEAIT
                     MEDCV"
     gene            13780..14958
                     /locus_tag="KR231_000379"
     CDS             13780..14958
                     /locus_tag="KR231_000379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation transporter"
                     /protein_id="HBH0002797.1"
                     /translation="MFSKILVKTFIRDSENVQNTDVRNKYGYVAGVVGILSNLLLFVI
                     KVFIGMLTSSIAIMADAFNNLSDMASSAITMIGFKLASKPADKEHPFGHGRIEYLSAL
                     IVAFMVMLVGLQFVKSSIERIVNPIPVKFEVIPLILLIASIMIKIWLSRFNKFMGNKI
                     DSSALKAVSLDALGDVFTSSCVVISFIVARFTNFPIDGYVGIVVSLVILYAGFSLVKD
                     TINPLLGEAPDEEMVNSIIELLLSYKYIIGTHDLIIHNYGVGRCIASIHAEIPSNIDI
                     MEIHEIIDTAEREISEKLDIYLVIHMDPICLEDKEVMSAKKELEEILKKNSLVKSMHD
                     FRIVGKGSKKNLIFDIVVNPSEFSKNMSEDDLKEDITKLVKEINPEYNCVIVVDKDFI
                     "
     regulatory      15085..15170
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01786"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="cyclic di-GMP riboswitch class II; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="cyclic di-GMP"
                     /db_xref="RFAM:RF01786"
     gene            15288..18206
                     /locus_tag="KR231_000380"
     CDS             15288..18206
                     /locus_tag="KR231_000380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_021362860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SrtB-anchored collagen-binding adhesin"
                     /protein_id="HBH0002798.1"
                     /translation="MKKGNRKALLISLIMILSMVVSTIYPTVSYASELGENSQIQSGS
                     TNSSTGEEKESDNKKPEQTPEKDKATDNKKPEQTPEEEKPTDNKKPEQTPEEDKSTDN
                     KKPEQTPEGEKPIDNKKPEQIPEEDKSTDNKKSEQALEDEKPLDNKNTEKTPEEDNLL
                     EDENLLKVLEEELNEENEDYGFVVKINNNTIETESMKKISFNLTYTPTSKGIQAGDSI
                     TFKVPDVFNKVNLDYTSECFDKTESNGEYTLTFRELPNGQSVMQGKIGLEAYVKKVDE
                     DTNAKIHIETTGKIESGSGDIDVEIKPGDKTDVPDAKGTLKKLVEGKKSTTVFMPVKN
                     KDINYSIQVNEKQEELKDIILYDELPEGLTLINGSVSVVTSDGKEVSDFNIEQSKNSI
                     SVNFGNIDKSYTVKYKARISDKNAKHGNKYKNVARIESDGKKIQEDDATVSIFDRGDD
                     YLLTKGHSGATNITQVGQVINYQISINDDKSPISNVVITDNIPEGMRLTTSGEAGHDF
                     RVVEIPMNGSWTPWSKEKIANNISYKVEEKRNESGQVDKVITGFTINLSKEEVESKFF
                     IAYTLKVISIEDSYINRAVLDANNSEIDKNDEINFKKNSGLISAKKEVDKKVLNSSDN
                     QIVKYKINMSTYGVYDAGQVNLLDEVNSALEISNIKYSDNLELKKEAGDGKNTIRLVN
                     KYEFKQIKEGEPVQSWVTFDADFTNVKVGETIQNVAQINGSSPPGVETTKQGYAFEAK
                     KVDALDKNVLSGAKFNLEDAFGNIVVKDLVSDEDGIIQSSIKKPGTYYLVEIMAPSGY
                     EKLKDKIKVEIGNKDIGRIVDIGNIENIRQENPPVNPPAPPNTDEPIVNPPVPPSTDK
                     PRKPSSSSDTEDTIVINPPIPPSEDIINPPIPEVLNPPVPPSEEMIETPVKQIIPIPE
                     VVKPSVSEEKNNKVKDDTLVNPPVPPKTGDSTTIIGEILLVIGAIVGLIVLRRNKNTN
                     "
     regulatory      18392..18477
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01051"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="cyclic di-GMP riboswitch class I; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="cyclic di-GMP"
                     /db_xref="RFAM:RF01051"
     gene            18577..19239
                     /gene="zmp1"
                     /locus_tag="KR231_000381"
     CDS             18577..19239
                     /gene="zmp1"
                     /locus_tag="KR231_000381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc metalloprotease Zmp1"
                     /protein_id="HBH0002799.1"
                     /translation="MRPSKKLLIAIISIFLISSVPVSAHADSTTIQQNKDTLSQIVVF
                     PTGNYDKNEANAMVNRLANIDGKYLNALKQNNLKIKLLSGKLTDEKEYAYLKGVVPKG
                     WEGTGKTWDDVPGLGGSTVALRIGFSNKGKGHDAINLELHETAHAIDHIVLNDISKSA
                     QFKQIFAKEGRSLGNVNYLGVYAEEFFAESFAYYYLNQDTNSKLKSACPQTYSFLQNL
                     AK"
     gene            complement(19361..20323)
                     /locus_tag="KR231_000382"
     CDS             complement(19361..20323)
                     /locus_tag="KR231_000382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EamA family transporter"
                     /protein_id="HBH0002800.1"
                     /translation="MKKGYVYIILTTLFFSSMEISLKTVTNDFNPLQITLSRFFVGGL
                     VLLPFAVKRLRALSLSITKSDLKYFAFLGFMCVVVSMSLYQLAVLNTKASVVAVLFSC
                     NPVFVMLLAYLILKEKIYRHNVISLILEVLGIIVIINPLHTKLTLSGIFLTLSSAIIF
                     SMYTVFGKRKTLKFGGIVVTCFSFIFGSLEMLILVLLTKINFIADILNKNKLHVFANI
                     PIFSGYTLHNMPIMIYVFVFVTGVGYALYFMAMEATSTSLTSLVFFFKPVISPILALL
                     ILKEIIPINMVIGILLIVIGSIISIIPTIITQMHNKHVEALYKE"
     gene            complement(20493..21683)
                     /locus_tag="KR231_000383"
     CDS             complement(20493..21683)
                     /locus_tag="KR231_000383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HBH0002801.1"
                     /translation="MISNKMQTLVANSSVIRAMFEEGKKLSDIYGEENVFDFSIGNPS
                     VEPPETIKAVINDILNEESPNLVHGYMNNSGYEDVRDAIAEHINKKDGLNLTRENLIM
                     TCGAAGGLNIILKTLLNPGDEVIAFAPYFGEYKNYTENYDGKLIEVPTNIETFEPDLD
                     ALKNAITPKTRALIINTPNNPTGVIYSEELLKNLGELLDSKQKEFNTSIYLISDEPYR
                     EIIYDGAKVPCVLKYYRNSFIGYSYSKSLSLPGERIGYIVANGQMDDFDDVMSSLNVA
                     NRILGFVNAPSLFQRVIARSLDAEVDVNIYKKNFDLLYNSLIDMGYSCVKPNGTFYLF
                     PKAPIEDDKKFCNDAKQFNLLLVPGSSFGCPGHFRVSYCVSYDKVKSSLPAFEKLAKL
                     YNLK"
     gene            21989..22435
                     /locus_tag="KR231_000384"
     CDS             21989..22435
                     /locus_tag="KR231_000384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HBH0002802.1"
                     /translation="MDFKNLQYESLSYIICNLQKNFKLYCEKCLKPYKLTNGLYFYLI
                     YINKNRNCSLNDVSTEFEVDKAHTTRTISRLEQDGYIEKIQNPNDSRAFQLRVTDKGE
                     EVLGDIKNIFSKWDNHIKKEFSDTEYKELVKNLHVVKDIKTAVEEE"
     gene            22437..23531
                     /locus_tag="KR231_000385"
     CDS             22437..23531
                     /locus_tag="KR231_000385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH:flavin oxidoreductase"
                     /protein_id="HBH0002803.1"
                     /translation="MYCNLLKPIKIGNLELKNRVSFAPTSMGLKLEEKIKKFSDIAKS
                     GVALITLGDVSIRPSFHKVAISLSDEDGVMKYKKIVDEIHNSGAKVSAQLFCSDYDVN
                     LIKDTMNMGITSHDEIKKIMNDGVKDYITNMPKEEIKNIINLFKVTALNAKKAGFDMI
                     QIHGDRLVGSFSSSIFNNRNDEYGRTCDNRSRFASEIISSIRDEVKDIPIDYKFAIRQ
                     ENPHYGNAGVLLSEVEYFVKKFESLGVNSFHVTLANHSKLEDTIPTNNHPYFKEEGCF
                     LYLADEVKKHTNLPVCGVGKLSSPDFIESIISNNRVDMVSMSRQLLADRNWLQKVKDG
                     RVDEIKKCCYCNKKCADALQTRSQFGCILD"
     gene            23619..24149
                     /locus_tag="KR231_000386"
     CDS             23619..24149
                     /locus_tag="KR231_000386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin family protein"
                     /protein_id="HBH0002804.1"
                     /translation="MKSLVLYSSLTGNTKKIAYTIYDEIQEEKDIKDVNELVDYSIDY
                     ENYDIVFLGYWVDKGICDKNSKQVLENIHNKKIALFGTMGASKKGSYGASIIEKIESI
                     IPKDNEILGSFICQGKIAEGLKAKYKEMLKLSPDNEHIRQQLNNHEESQSHPDEQEIY
                     EASMFAKNMMIKASIV"
     gene            24476..24835
                     /locus_tag="KR231_000387"
                     /pseudo
     CDS             24476..24835
                     /locus_tag="KR231_000387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891108.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
     gene            complement(25086..26462)
                     /locus_tag="KR231_000388"
     CDS             complement(25086..26462)
                     /locus_tag="KR231_000388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0002805.1"
                     /translation="MKYKIGFLTTSYFMSDKFKQALKELNDTCEITFIELKGENPFNN
                     LPNIYYEQVDNFDGFVCSGIVPYSELIINIKDIKVPLNFLKLDERDFYKYLFKLLNSQ
                     KDIDFTKSFMDFLREDNNYYDIYSLIDSNKCPYTIKDFNIPQPVYDFKKLNDKLLEIH
                     LDLLRDNKINLSFTRNYIISCELNKLGYDCIYMVPSTESILNTFKSLVNEITLQNLDK
                     NKSATCIVTVNSSEYINEDLIFKNDEIQNQIYNTILNSLSRHGFYGVQVKKNDMKIEI
                     HTTKEMLNNMTNNYTDFFISEDLKEIKYSLNIGWGIGNTNIHAEQNARQANGKSASLN
                     GNCTFIVNDTNDTIGPLYSNKNSNNIEDSSIANKVASFIPLSNTNVSKIMCMINDRNS
                     NNVSAEILSNYMNITLRSANRILSILYKAGIATIVNTKLDNQRGRPKKIYKVDFLSFL
                     NKMQKLNS"
     gene            26730..27902
                     /locus_tag="KR231_000389"
     CDS             26730..27902
                     /locus_tag="KR231_000389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallopeptidase"
                     /protein_id="HBH0002806.1"
                     /translation="MNTYLNEISKFVDENREEIVSLWKEIVNIESYTHCKESVNKLAK
                     RLKFEFEKEGLDCELVDVGDNGSTLIGTLGSNINKKPIIFSGHMDTVFETGTFGENPF
                     KIIEGKAYGPGVLDMKGGIIISLYVIKALNKIGYKERPIKIVFSGDEEIGHKDSTGAD
                     VILREAKGGLCAFNMETGLVDNSLCVGRKGRIGCNIHVKGVETHAGNDFEGGRNAIEE
                     MANKILRIQKLTNLDVGTTVSVSVIKGGRVENSIPEDCSIKVDLRFEKVEEMENVKEQ
                     VREICKETYIEGTSTEVNFISEMMPFETTEDVMRFHTFVNEVSKENGFGELNAKRLGG
                     SSDASYLTIANVPAICSFGVRGEWNHTSREYAVVDSMFERVKLISTVILNLDKFEV"
     gene            27916..28563
                     /locus_tag="KR231_000390"
     CDS             27916..28563
                     /locus_tag="KR231_000390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0002807.1"
                     /translation="MDVTAGDNKVTWKGYLSLFVLIVLFSGVFKDSQGFLKALDFANL
                     TGSFGTIADGVDFMGKGGTGAKDGFLFALTLIPTVCFAVGLIDVVESMGGMKAASKIF
                     NPLLRPLLGIPGIAGIAFVSSFTSSDVASIMTKELFESGEITDDERTIFVAYQYAGSA
                     VILNTINTQAPLLPIALLALGPIILIEIFCKILGANLVRLIIGVRNKKNKAKEAV"
     gene            28565..29074
                     /locus_tag="KR231_000391"
     CDS             28565..29074
                     /locus_tag="KR231_000391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside recognition protein"
                     /protein_id="HBH0002808.1"
                     /translation="MSQQNTGNAIVNSKPKKTAVEIFMGGAKKGFYIGVEQILPAMIM
                     GYVIVQFLQLTGLVDILGNIFGPVMGIFGLPGESVLVLIAAFFAKAAGAATAANLFAQ
                     GLITAPQATILIMPCMLMGTLVGHYARIVLVANASTKYRMLLLAVPIFDAIVGMLIVR
                     VLLTVMGLM"
     gene            complement(29438..30550)
                     /locus_tag="KR231_000392"
     CDS             complement(29438..30550)
                     /locus_tag="KR231_000392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine racemase"
                     /protein_id="HBH0002809.1"
                     /translation="MKISEVATPNFLLDLDQLEKNIDKIQQICTNNNKQLWPMLKTHK
                     STYIARLQKNAGASGFLVGTLDEGEALIKAGFEDIMLAYPYMGEVNINRIVTMASKIN
                     LICATDNIECAKAYSEAFSKSKIECKLLIIVDCGLHRFGVEPEKVVELATEISKLENI
                     KIVGISSHPGQVYGCSSPEGVPDVCVQEDSSMEKAYKALTDNGFNIEIVASGSTPTVE
                     SEAASKTITAVRPGNYVYYDAIQIGLGCATEDMCALTVVCTVISKNSSGYYLIDCGSK
                     CLGLDKGAHGNSSIVGYGRVCGHPELTIDSLSEEVGKIKVNGETDIKIGDRIRIIPNH
                     SCSTANLTSNLLGFRGDTIEKVIEVDIRENSKQIIL"
     gene            30848..31114
                     /locus_tag="KR231_000393"
     CDS             30848..31114
                     /locus_tag="KR231_000393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase family protein"
                     /protein_id="HBH0002810.1"
                     /translation="MNLEPKKLIEQIGKEKDKKDIWIVGGGDIVKLFMKDNLIDDYYI
                     YILPIILGRGISLFKSGIDKTNLNFKKASNIGELVKLEYSKKQK"
     gene            31359..33086
                     /locus_tag="KR231_000394"
     CDS             31359..33086
                     /locus_tag="KR231_000394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003496244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH0002811.1"
                     /translation="MKLILSYLKNYKLLIVLNILAIFSFALVELGIPTIIAKIIDNGI
                     ANQNIAYIKQMGIVIVIISIIGVVGSILLGYCSAKVSTSVTRDIRNDIFEKSQEFSHT
                     EYNKFGISSMITRTTNDAFQIQQFVNILLRTALLTPVMFIISIIMTIRTSVELSIVLA
                     ISVPFIIIGVAIIAKVSQAISSKQQKGLDKLNLISRENLTGIRVIRAFGNDDYETERF
                     EKTNTYYANVSKKLFKLMSITQPAFFLLLNIAVLAVFWISSEKINIGELQVGQLVAFL
                     EYLFHAMFSIMLFSMVFIMYPRAEVSANRIKELLNEEPLIKNPENGIKDTENKGIIEF
                     DNVTFTYPDGEASVLKDISFTAKTGETVAFIGSTGSGKSTLINLIPRFYDVTEGSIKI
                     NGVDIREYDLKALRKKIGFIPQKSLLFTGSIANNIRFGKHKAGESELEYSAKVAQAYE
                     FISKKPRKFDELISEGGANVSGGQKQRLSIARAIIRRPEIYIFDDSFSALDFKTDAIL
                     RAKLKKETKDAIVLIVAQRISSIIDADKIIVLNEGQVVGMGTHKELLKNCEIYYEIAT
                     SQLKKEELE"
     gene            33086..34876
                     /locus_tag="KR231_000395"
     CDS             33086..34876
                     /locus_tag="KR231_000395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426617.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH0002812.1"
                     /translation="MKKSKGFKKTIGRLLPFVKKYKFSFIIAIICIISAATMNALAPK
                     TEGLIITQLTKDVISIAKGVPGASVNFDYVTKILVILACIYFANAIFTYTSSFLLTNA
                     IQNTMRDLRNEVENKIRRLPISYFDSNSFGDVLSRISNDVDTISNALQQSFMQIVNSI
                     LVIILALSMMFTINIYMALIALFIIPISYFVSKFVVKKSQSRFSLQQNALGKLNGKVQ
                     EMYTGFNEIKLYGKEEDSIKEFKKVNQELCENGFKAQFISSMMNPMVSLVTYFGIAAV
                     AVVGSIYAVSGGITVGNLQAFVRYIWQINQPLSQMTQLSTVIQSSFAAIERVFEILDE
                     EEEIPDVENPVKIENVKGNVTFEHVNFGYGENSTLIEDLNAEVKSGQMVAIVGPTGAG
                     KTTLINLLMRFYDVKKGAIKIDGVDIRDMKRKDLRSMFGMVLQDTWLFNGTIFENIEY
                     GRFGATKEEIIQAAKVANVHHFITTLPDGYNMFLNEEASNISLGEKQLLTIARAFISD
                     PSILILDEATSSVDTRLELMLQKAMRNLMNGRTSFVIAHRLSTIRNADLILVMNNGSI
                     IEQGNHDELMEKGGFYEKLYNSQFADKESE"
     gene            complement(35038..35346)
                     /locus_tag="KR231_000396"
     CDS             complement(35038..35346)
                     /locus_tag="KR231_000396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0002813.1"
                     /translation="MFNKIYEKKEFIVFQVKKGYVVYNTRKSFEEGHTHLKHFEAAKT
                     AIDLAINKKIPRSKDGYYLTSLIRISDDGYYIDKLSELLYVREQKGKKEKYCNSGYQM
                     "
     gene            complement(35608..36156)
                     /locus_tag="KR231_000397"
     CDS             complement(35608..36156)
                     /locus_tag="KR231_000397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0002814.1"
                     /translation="MIFLNEDVVTNETIDKDYAIEEVRMACKHFGDLYFYFSKVLFEE
                     FGEDKTSEILRKVLFERSEERAIAMRERAHENGDELIADNIISTTDVPFLGWVPEFEE
                     LHCPYGASWLLRFEENPWFKKFASLYCDVTDTTVAEVFTGDTSHKITKNILWGDKSCE
                     RIYFHDDKVSEGKYTYGNKNCK"
     gene            complement(36259..36930)
                     /locus_tag="KR231_000398"
     CDS             complement(36259..36930)
                     /locus_tag="KR231_000398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBH0002815.1"
                     /translation="MATFKRLQEQAYDYLKELILSGEMIENEIYSETKLASEIGISRT
                     PIRDALQRLSQDGFIDIIPSKGFRIHQITANEIVEIFQIRSAIEGFCTFLITSQYKEA
                     RAVETISKLKHLLDKQKDILLGDKNLNSFAEYDTLFHTTIVSYAQNTEFDKMFNNYMY
                     RIKKLALDSLSHEGRLETTLKEHTDIFNNIANGCIEDIYRTTLIHMETPKYINLEDFC
                     NNKLF"
     gene            37326..38231
                     /gene="garR"
                     /locus_tag="KR231_000399"
     CDS             37326..38231
                     /gene="garR"
                     /locus_tag="KR231_000399"
                     /EC_number="1.1.1.60"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-hydroxy-3-oxopropionate reductase"
                     /protein_id="HBH0002816.1"
                     /translation="MEGYKMKLGFIGLGIMGKPMAKNLLKDGCNLLVYDINKSAVDEL
                     ISCGAKYASVLEMGQECDIVFTILPNGTIVQDILFGMDGLAKTLKEGSIVVDMSSVTP
                     TESILCANKLKDMGLEFIDSPVSGGEPKAIDGTLAFMAGGKEEIYKKVEPFFNIMGSS
                     SILIGDNGSGSVTKLTNQVIVNLTIAAVSEAFVLAAKAGADPEKVYKAIRGGLAGSTI
                     LDAKIPMIMNRDFKPGGKISINLKDIKNVMQTAHNLDVPLPMTSQLLEIMQTLKVHGH
                     LEDDHSGIAQYFEKLAGVEIKKHNN"
     gene            38367..39749
                     /locus_tag="KR231_000400"
     CDS             38367..39749
                     /locus_tag="KR231_000400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntP family permease"
                     /protein_id="HBH0002817.1"
                     /translation="MITGYGLLIAFVISIGILLVSIIKFKVNPFLALLITSIITGFMV
                     RMPINEISTTISTGFGNTLGSIGIVIGLGIIFGNILSESRATESIAKGLLAKTGEKNS
                     ALAVTTAGFLISIPVFMDAAFVIMMPIIKYVSRVTKKSLMVFVCALGVGTIVGHALVI
                     PTPGPLAVAANVNANVGSFILYSIIVAFPAALIGGWIYGKRFEKYPAYAIDENDREKN
                     LEQGKDSIKIEDDDSSKVPGFGISMFSLLFPILLILISNVFSMFLEKGSTMSGVLAFI
                     GDKNIAILLGILVAIGFLKKYINKPMGDVVIEAADSAGLILLITGSGGAFGSVINASG
                     IGNFLVDTMSGLSISVVVLGFLLSALLRISQGSATVALVTTSSILGPTILATGMSPVL
                     VGLAICAGGVGFSLPNDSGFWVLSRFSGLSVKDTLNSWTIGGTIAGVVAFIMVLLLSV
                     INGIIPLPGL"
     gene            39820..41256
                     /locus_tag="KR231_000401"
     CDS             39820..41256
                     /locus_tag="KR231_000401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxyacid dehydrogenase"
                     /protein_id="HBH0002818.1"
                     /translation="MREVKPISIDILNTFKQVDEDRLNKLLADELKHLDRKIVVLDDD
                     PTGVQTVHDISVYTDWDKDSMEQGFNEKNSMFFILTNSRGFTVAQTTKAHKEISKNIV
                     DVSKKVNKDFIIISRSDSTMRGHYPLETNLLKSEVERLSEKLFQGEIIMPFFKEGGRF
                     TIDNVHYVKEGEILVPAGMTEFAKDKSFGYKSSDIGEWCEEKTNGKYKSSDMIYISSK
                     ELRELNIEAITEKLKKAEGFNKIIVNATDYVDVKVFTIAFIRAVNSGKEFMFRSAAAI
                     TKILGGVSDKELLTKDELVSKGNTNGGIILVGSHVNKTTQQLEELKNCKYPIEFIEFN
                     QHLVLQENGLKNEVKRVIKVVEEKISRGKTVAVYTRRERFDLDTNDKDKQLMISVEIS
                     DAVTSIIGMLNVRPNFIIAKGGITSSDVGTKALRVKKATVMGQIKPGIPVWMTGKESK
                     FPNMPYIIFPGNVGEISTLRESVEILMG"
     gene            complement(41442..42296)
                     /locus_tag="KR231_000402"
     CDS             complement(41442..42296)
                     /locus_tag="KR231_000402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0002819.1"
                     /translation="MSTFYIQFLYFVIYSFIGWCCETTYCSVLQKQFVNRGFLNGPFC
                     PIYGFGALAIVATLTPFVHTIPLLFLFSIIITSIMEYCTSFILEKIFNMTWWDYSKHK
                     FNIHGRVCLENSLMFGVLSLIVMLIVHPIVVDFINSISKNVLFIFAISIEIYFVLDLV
                     ITVHTILQLNGKLKQINLIIKELKDKKEYYKLITQETIENKLESLVENRLDTLEDRFE
                     ILKEKENYRYAKNRIDELKNKLNTLLSNHKLLHRRIIKAFPNISSNKHTDILNKIKEN
                     IKSIKKDK"
     gene            complement(42564..42887)
                     /locus_tag="KR231_000403"
     CDS             complement(42564..42887)
                     /locus_tag="KR231_000403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1540 domain-containing protein"
                     /protein_id="HBH0002820.1"
                     /translation="MERINCNVINCSHNNSHICYADKIFINGEKAHNDRHTCCSSFLD
                     ESIYSNLSSNVNNRNCEELVCTVKNCKYNKDGSLCTLDNILVAPETDRVNLYIETCCS
                     SFECK"
     gene            43090..43719
                     /locus_tag="KR231_000404"
     CDS             43090..43719
                     /locus_tag="KR231_000404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0002821.1"
                     /translation="MFEKKKKELFPWKISALILVGVFVLSSGVYIGTRLKHNGVQTGE
                     VVSTSANMNEKSKEAFGLNKNCEVWLQSEGENETNYKRTLTMAGIVPESLLDKTKSEI
                     VSYFKKEYPTKKIKSMDKNEIILVESKYSDNKDVQAMDVTIKGKYTIENDNGNIALYK
                     YDDSGSKTLVEKTKIRVDSLPKTVQDEIKKGVVMDTEEEAYSRLEDFAS"
     gene            44062..44571
                     /gene="ruvC"
                     /locus_tag="KR231_000405"
     CDS             44062..44571
                     /gene="ruvC"
                     /locus_tag="KR231_000405"
                     /EC_number="3.1.22.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="crossover junction endodeoxyribonuclease RuvC"
                     /protein_id="HBH0002822.1"
                     /translation="MIILGIDPGIAIVGYGIIEYKNSKFKVIDYGAVTTPAHMNISRR
                     LELVYKGIDTIVKNYNIDEVGMEELFFNKNVKTAITVAQARGVTMLACAHNGKPVYEY
                     TPLQVKQGVVGYGRADKAQVQQMVTSFLSLKKVPKPDDVADALAVAICHAHSNKLEKT
                     LKNIGGKYV"
     gene            44564..45166
                     /gene="ruvA"
                     /locus_tag="KR231_000406"
     CDS             44564..45166
                     /gene="ruvA"
                     /locus_tag="KR231_000406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration protein RuvA"
                     /protein_id="HBH0002823.1"
                     /translation="MYSYIKGTVEEIYIDSIVVENNGIGYKINVSSNTIMNLQVGEAT
                     KIYTKLIVREDDMSLCGFVSREELKMFELLTSVSKIGPKVALSILSFASPAQLGAYIL
                     SEDIGKLSKAPGVGKKTAERIVLELKDKVDKNNIEFEPTLLSQKPTLISQDESVDALV
                     ALGYTLSESKEAVQKCKKDGMNTEAIIKKALTYIMSKSLK"
     gene            45273..46292
                     /gene="ruvB"
                     /locus_tag="KR231_000407"
     CDS             45273..46292
                     /gene="ruvB"
                     /locus_tag="KR231_000407"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration DNA helicase
                     RuvB"
                     /protein_id="HBH0002824.1"
                     /translation="MQGFEDENRIITSTMKMEDIDIENSLRPKTLEDYLGQEKSKEQL
                     SIFIEAAKSRNEQLDHVLLYGPPGLGKTTLASIIANEMGVNLRITSGPAIERAGDLAA
                     ILTNLNENDVLFIDEIHRINRSVEEVLYPAMEDFCLDIIIGKGPSARSIRLDLPKFTL
                     IGATTRAGMLTNPLRDRFGVICKLDYYTVDELSKIVLRSSSILDAEIQSNGALELAKR
                     SRGTPRIANRLLKRVRDFAQVRADGKITDKVAKDALELLGVDSLGLDFVDEKLLMTII
                     EKFRGGPVGLDTLAASIGEDRNTIEDVYEPYLLQLGFINRGPRGRVAMPLAYEHLKIP
                     YPNEK"
     gene            46610..47635
                     /gene="queA"
                     /locus_tag="KR231_000408"
     CDS             46610..47635
                     /gene="queA"
                     /locus_tag="KR231_000408"
                     /EC_number="2.4.99.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA preQ1(34) S-adenosylmethionine
                     ribosyltransferase-isomerase QueA"
                     /protein_id="HBH0002825.1"
                     /translation="MKTSDFKFDLPQELIAQVPIEDRASSRLMVLDKETGNIEHKVFR
                     DIIEYLNPGDCLVLNNTRVIPARLIGEKLETGGKIEFLLLKRTEEDTWQALVKPGKRA
                     KVGTKFSFGNGKLIGEVVDLSDEGSRIIKFHYDGIFEEILDELGNMPLPPYITARLDE
                     KERYQTVYSKHNGSAAAPTAGLHFTEELLNKIKEKGVDIAFVTLHVGLGTFRPVKVED
                     VLNHKMHSEYYMVSQEAADKINRAKENGKNVICVGTTSCRTIESACNEYGKMKETSGW
                     TEIFIYPGYKFKVLDKLITNFHLPESTLIMLVSAICGKDNVLNAYNEAVKERYRFFSF
                     GDAMIIK"
     gene            47647..48132
                     /locus_tag="KR231_000409"
     CDS             47647..48132
                     /locus_tag="KR231_000409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422818.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0002826.1"
                     /translation="MHSLQKQKKNNPILKIAFIFERVLAVVVLIAVFLGTIDVLRLMW
                     GAYIVDFQNPVQYSQLNDFLAQILLLVIGVELVVMLSLHIPGAFIEALLYAIARKMLL
                     LPKNEGMIDVLIGVIAIAGLFAIKKFLVTKDKSALNIMSIHDEEAIKEQQNKEDEDKS
                     I"
     gene            48211..49332
                     /gene="tgt"
                     /locus_tag="KR231_000410"
     CDS             48211..49332
                     /gene="tgt"
                     /locus_tag="KR231_000410"
                     /EC_number="2.4.2.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA guanosine(34) transglycosylase Tgt"
                     /protein_id="HBH0002827.1"
                     /translation="MYAVRYELIKTCKQSGARLGRLHTPHGIIETPIFMPVGTQATVK
                     SMTPEELKEIGSQIILSNTYHLYMRPGHELIKRAGGLHKFMNWDKPILTDSGGFQVFS
                     LGPLRKIKEEGVEFRSHLDGSKHFLTPEKAMEIQNALGSDIMMAFDECAPYPSDREYV
                     KNSLERTTRWLKRCKDAHNNTDKQALFGIIQGGMYKDLREQSAKEITNIDLPGYAIGG
                     LSVGEPKPLMYDVLEHTTPLMPKDKPRYLMGVGSPDDLVEGVIRGVDMFDCVLPTRIA
                     RNGTAMTSQGKVVVRNATYAEDFTPLDPECDCYACKNYSRAYIRHLIKANEILGARLI
                     TTHNLHFLLNLMKQIRQAIMEDRLLDFRNEFFAKYGYEI"
     gene            49466..49759
                     /gene="yajC"
                     /locus_tag="KR231_000411"
     CDS             49466..49759
                     /gene="yajC"
                     /locus_tag="KR231_000411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit YajC"
                     /protein_id="HBH0002828.1"
                     /translation="MPQQQIIMSIGLWVVVIAIFYFLMIRPQKKKDKQLKEMRSSLSV
                     GDKVITIGGIVANVAKVEDDVVILELGPNRTKVPFEKWAIGTVKSKKEEIEED"
     gene            49817..50179
                     /locus_tag="KR231_000412"
     CDS             49817..50179
                     /locus_tag="KR231_000412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR04086 family membrane protein"
                     /protein_id="HBH0002829.1"
                     /translation="MGKSNYIFKGLGYAYIITLAVLLVYNLFLTFTDIGGDNITMVSS
                     FITTISAAIGGFYTSKHMKEKGLMYGLLVGLLYIVCIFLTVFLAQEKFVFEIGMIYKL
                     LLISAAGGIGGVLGVNFK"
     gene            50245..50388
                     /gene="scfA"
                     /locus_tag="KR231_000413"
     CDS             50245..50388
                     /gene="scfA"
                     /locus_tag="KR231_000413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="six-cysteine ranthipeptide SCIFF"
                     /protein_id="HBH0002830.1"
                     /translation="MENKHVKTLSQATLKQSAAKGGCGECQTSCQSACKTSCTVANQE
                     CER"
     gene            51015..52910
                     /locus_tag="KR231_000414"
     CDS             51015..52910
                     /locus_tag="KR231_000414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861692.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp8"
                     /protein_id="HBH0002831.1"
                     /translation="MLSNKKRSMAIVMAGATVMSAAAPIFADNTVTENVDKNYTVSAK
                     DSAKLIEEVRKALEVKFEDTKAGANVNDRVYDIKVDNVNLTNATQLQNKINSLTEGQS
                     LKVTIQDKGHQVLGGKVVDYKIENYKTAQEIVDAVNAYNATLAEDSDNKLTATIKSTN
                     TVEVKRAKDSANVITLNVGDQHLDFSKVITSEEGTFEGYEKSYSDIDSKELHTITVKN
                     ADLQDISAEELFDGIRLTTLGREIVNKVKNGYALTFENEAILTQEQEDSDDKDKPEKS
                     SFDIVLSKANEKPETISVSSKNHKLVRDLHKVLTDVKDGKELKVEVLSGDSRFTTAVE
                     VSKERFKDGEAEAIILVGEDAIVDGLASAPLASQKNAPILLSKKDSLPSEIEAEILRV
                     LGSNLSSKKIYIVGGESKVSKETEEKLSKLGVSKVERVSGEDRFETSLEIAKQLKDTF
                     KTAFVVGGNGEADAMSISARAAQFGAPIIVTGNELDANAEKLLKGKELEIVGGENSVS
                     KEVEDKLVDIDLNNKVERLAGENRKDTNAKVINKYYAGATKAYVAKDGYVGGNGQLVD
                     ALTAAPLAASSKAPIVLTTEELSKSQEEVVELRLKNATKLVQIGEGIAKNAIEKIAEK
                     INLFTKN"
     gene            53372..54775
                     /locus_tag="KR231_000415"
     CDS             53372..54775
                     /locus_tag="KR231_000415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp9"
                     /protein_id="HBH0002832.1"
                     /translation="MKNSKKILAIGLTLFLVMVNTPMVNALTSVEQIKGNDRYETAAK
                     IADKQNYNTAILINSDNSLADGLSASGLAGALNAPILMTKQNQIPNTTMERLNKAKTV
                     YIIGSESTISKNVENQLLSKKKVVQRIFGENRFDTSIKIAEKIKEIKPIDKVIIANGF
                     TGEADAISASPVAARDGVPIILTDGNSVGFDTTGLKSYALGSSEIISDELVKSTNSIR
                     LGGTDRFETNKIVIQEFYKNSKEFYLSKGLQLTDALAASTIAKNAPVVLVENGSNKSI
                     LSGADKLTVLGGINQNVIKQCINQASPNQQGLYYNPNDRAFKERIKGKVYALTKQYRK
                     ENGVRALSVASRLEGLANDWSNLMANKKTLSHTINGKNSYSTFLKYLDWSEIKPGYIA
                     VQGENIIKYKIPDKPVYTNRDADDIGNFIFNEWKTNPEEGTNMLHKGYEIMGFGIAIT
                     GDKNLYATHEFYGRYKE"
     regulatory      54947..55032
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01051"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="cyclic di-GMP riboswitch class I; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="cyclic di-GMP"
                     /db_xref="RFAM:RF01051"
     gene            55156..61119
                     /locus_tag="KR231_000416"
     CDS             55156..61119
                     /locus_tag="KR231_000416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="calcium-binding adhesion protein"
                     /protein_id="HBH0002833.1"
                     /translation="MKKAISCVLAVSMCSAPLNVFAEPILEGKLRAVEKSVTEKLRGS
                     LEVDLNFSLPIKNSESESMTNMQLRLKDDSNNSGIIKLGEKDSGTVNVGTDNIEYTIK
                     KLSASRSEIKNKDENISYYNIVFNNLPVGKYNVEVSGDGFKNKEIKDIDISSYSQRVL
                     LSNRASVDNKNKPLNYELFLMGDVNGDGKVDKSDYNKVLENIDSNKREFDLNRDGKVD
                     IVDLDYVQKNLGQSEDAKSLESIVSTNPIVDTSKVELKGNSDVDINGNVENLFSGENN
                     GVTISSKNDEISEEKPAVMDIALSEALNMEVINIKAPEGTAPAKGIVEVTDKDGNVQQ
                     IPYENKEYMKNLKDEEQQEEVNNEQEEVNQEEVNNKDENINQTDNNSNNKDENNDKQQ
                     ENSDKQEANSNTNQDKNNDKENSSMDKPNSDEDTPKEEGNISKDDNSTTSTYSRSALE
                     TYADVQNSDIVINLGKQVAVKKITIKITATTANDRNLAEISKVEFLNNVYKEIPKPEM
                     NIPKINKISTSTAVGNEKVSFYWNNEVNVSAYELILDKIDSKGKVLSTKKLQTSKNTI
                     EVRDIEAYGLYRVSIQSLNGDWSSGYKDATPENLDGVPENVDSNYKPIQFSPDSILEF
                     QVVPDTKPEPPEGINVKGKFKSLDVSWKNHKQAKDFDLYYKEKGSNGSWIKYNDKLIR
                     GTSSKIEGLKDNTTYEVRMTATNHLGTSGMSKTYIGTTESMDAPTTPNYRLINTPKEN
                     GGFGIPTNHIVDVVYPDGYDKSEYSDKNPFDKFNVVDGDFTTHWTFPTYNAAEGTNRG
                     PIITFDKSYTMDTFMATPRFDVSDKTINDFEVRYWDENGQLHNLGDVPFETKTDPVNN
                     NKYVMVRLKEPITATKIQVSVCSSYSYKSNISELKFYEYDSIEDDVRNLFMDGLQVEL
                     KEDVTQEKITELKDRLNTPDKASGEYHPYKTVIERELKLAQDLYNDRATLTDVTTVNQ
                     EINKLGKYKDKNGQYTVNSNNLGMQNDWQALGVAARAGDEITVYVGSKSGKTPKLIYT
                     QYYGESGAYKSGEINLNTGKNVIQLSKLHSLDIECGGSLYIRYAEDTPSGGDIKVRVA
                     GATKIPHLNLNGTINDKSPAGVSESKKKIKAYIEELAKYKDAVKGEPYYPGTNVGNSY
                     GYSEKTGVLNTTDIESDKVTLNVPATAVYQEISKGNSDLNTQVDRLYNSMLAWEQIMD
                     LVYSERGVFKTQDLDGNGTVDDNEFNLTKNDMAPKSRMNIKYQRMFIGAFMYASGLHV
                     GVEYGSVPGLMNGVPFQIDDSGKATGGNLFGWGIGHEIGHVTDIGKMTYSETSNNVLA
                     LLAQTFDDKTHSRLEGSTMDKIYEHVTSNSLGIPSNVFERLGMLWQLHLAYDDDFTGS
                     MLKNNSDADLSNDTFYAKISRKYRALSSSDPINSLPKDQMLVAMASSVVEKDLRDYFK
                     AWGVEITPELNSIMDSKNYEKESRKIQYVNDEARRKILNENIASMAKDTKVSASFSDG
                     IQSGSLVKSNKISIDLDVDKDKDKILGYEIIRSDGNYLDGENGTQVKYRTVGFVDAKG
                     NSKTKFTDNISPLNNRAFTYKVVAYDYHLNPTEEFEVGTVKLSDEGKINKSAWSFITN
                     TVSDGDVRTENDSHGPLQNPEIDNIKDNDASTTYKGKIISKAEWNKDPQKDPDINVEE
                     NPYIIVDMKETLPIVGLKYTKPETEARKFSLKGLFNFRKNTSTTYNPLTNYKIQVSND
                     KKNWEDVSQGTFEYGQDLVGGGKDQDNEARVTFNKDGKLWTYQARYVKLISNNKSNIE
                     VAELDIIGPPGDNIEIGIINNADETRTNGIGKLAEDYVYQSDDSSTSEDETGKIPAGS
                     IVITGEYSGNPAFNLPLLIDKNNKTISGEALLFAEVPEKGELGEISKGTWVYYMPKEN
                     FDSLSDKVKAELYRYNDLQGDTPVGQRFVSDTMYVPVGAKNYDELKTISLTDSNSKAR
                     KATRNSIDISNKKVITVSNKVKGNIVRDK"
     gene            61323..63203
                     /locus_tag="KR231_000417"
     CDS             61323..63203
                     /locus_tag="KR231_000417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp10"
                     /protein_id="HBH0002834.1"
                     /translation="MSKRKSFIRTIAVSTMAVAVTGSATCAYAAPVLQGTKTYEKVNT
                     IDISVDSVENIVYSFQASIKVQGEVEVVDNEQKEKITWSDNIKSQIKSGNANATCRVE
                     YNKSSNTTTLDIYVTSNEDLLDGNRLNIGRISVKKSGSNSNADYKVLGKGTNDKPALK
                     IVTYNNKTVDYENISSDEGLIFTLINESEVKPIGGTGSSKNDPEKYKVEKSEALEYLL
                     NNIRINYSIVSKETQESGSNVILKLGLAQKTTKGRKATINKYVEVTLPKSLEYIVENE
                     LSKPDELPPDNGNGGNNGGGSNSGGSSSGGSSGGGSSSDSTSNVTVKKLKGADRFETA
                     IKISQSGWTKSDTVVIVNGEDKSMVDGLTATPLASVKNSPILLSSNEKLPQKTVEELK
                     RLNPSKVIVIGGNNSMPNSVVEAIKAVNSKISVQRIGGDTRYQTSINIAKEIDKTNNV
                     SKLYIGAGNGEADSLSIASLAGKEKTPIVLTQKDGVDNEAEQFIKSNKVSNIYFIGGV
                     EKISNKAIEQVGKIANKDISNNRVAGQTRQETNAKVIDKFYSQSKLDGVVVANQDKLI
                     DALAVGPLAAKNNSPVILATNTLDKSQESSLKGKNSSKLFEVGGGIASSVIDKIKSLI
                     EK"
     gene            63570..65171
                     /locus_tag="KR231_000418"
     CDS             63570..65171
                     /locus_tag="KR231_000418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp11"
                     /protein_id="HBH0002835.1"
                     /translation="MKMNKKILSLGLAVSLILVNFKSVNASSVVEKIYGKDRYETAAK
                     IADKQTYETVILVNTEKSLADGLSASGLSGATKAPILFTQQNKIPADTNRCLKNIKKA
                     YIIGTEDTISKSVEKELDSKNIEVKRIGGEDRLKTSYLIAKEIATIKKVDKVLLTNAY
                     SGEADAMSVSSVATRDGAPIILTDGKSVPFDVKNIQSYCIGSEEIMSNPLVKNTNSVR
                     IEGTDRFETNKNVIDYFFNSADGFYVSDGYQLVDAIAAAPLTKNSPMVLVNDGSDKTV
                     LEGAKNITSVGEINEKVIQQCINASNSNGQPPTITVGSTEVYKGEKFDTGKLNIVAKD
                     NTGKVLPIEVDGFIDTNRVGTYILTLKATDEWGKSTGKRVEIKVLDDKSHDYNSPEFK
                     KMVSTEMYNLINSYRKEKGKEPLLVSSRLEGMANAWSKYMMDKKVFAHYIDGKNAPQV
                     FSEFGMRSEENIAYIYIDSKNVQTTQDAKDLAKAIFEVWKKSPEYNANMLSNEFYSTG
                     FGLYILSDGQVHATQEFLNGNEGSL"
     gene            65390..66988
                     /locus_tag="KR231_000419"
     CDS             65390..66988
                     /locus_tag="KR231_000419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding repeat-containing protein"
                     /protein_id="HBH0002836.1"
                     /translation="MKVNKRVLSIGLTISLIMAGAPNINALSSIEKIQGKDRYETSAL
                     IADKQIYDTIILVNTDNSIVDGLSASGLSGVAKAPIMLVQRDKIPTDVEKRLKDVKNA
                     YVIGTEDTIGKSVENQLKNKGIEVKRIGGEDRIKTSYLIAKEISAIKPVNDGDKVFLV
                     NGYTGEADAMSVSSVAARDGVPVILTDGKSIPFKVDGVQCYSLGSEEIMSNELVSKTN
                     SVRIAGKDRFETNKKVIQRFYKGTKKFYVSQGYKLVDAVAGSPLAKDKPIVLVNDGSD
                     KSVLRGADEVTSLGGMDKKVVDQCISSASDKNTMPTITANDVEISVGDKFDNSMLNIV
                     ATDYYGNDLKANIKGNVDINKAGTYVLNISVVDNLGQKSEISVNVKVVVNASTKDSNS
                     YEFKAMVSNEMYDLVNSYRKEKGKKSLRELDSLAGMANAWSKYMEDKKVFAHEIDGKN
                     AAEVFFGFGARSGENIAYLPMNVKSVYTSKDAKEMAESIFDLWKKSSKYNENMLKEEF
                     YSFGFGMHVSSKGEVNATMEFLNS"
     gene            67278..69476
                     /gene="slpA"
                     /locus_tag="KR231_000420"
     CDS             67278..69476
                     /gene="slpA"
                     /locus_tag="KR231_000420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-layer protein SlpA"
                     /protein_id="HBH0002837.1"
                     /translation="MNKKNLAMAMAAVTVVGSAAPIFADTTVKEEGYTVVQDKYEKLL
                     KELKAKIKDGTITSVGVEFDGKPITTLAPKADGSDKDAIAEQLETLTKNQLKGLGDGK
                     YVDFKITYGAKAEVPAASLSADDIQKYADQINASEKILVEVAAGSEAGIAKFDSVNNK
                     VIAGDAPLKVKDAVKATVTTNGSNKKVLTISAAAGLSGFSYGTLKDTGASSSDVDAIT
                     LDTTNATITEGDTKVLDFDNSFKFNESTKKVGSLVTPNTTNTPADPGTKTTVRVIKAV
                     EKTIDVSSNSTTKAKDLAKQYVFTDVSDTDPESLSYMLKNINDGKVAVKNSDGDYEVT
                     IFPEGKRLNTLSASSAKTILGDKDTPAKIVLKASTTKKLADYIDDLITYNNSYSNVQT
                     VAGSDRIETAIELSRKYYNSTDKNALYGDPVNNVVLVGSQAIVDGLVASPLAAEKDAP
                     LLLSSKDKLDSSTRAEIKRVMDLNSSTGIKNNKEVFIAGGVNSISKDVENELKDMGLK
                     VTRLSGDDRYETSLAIADEIDINDKAYVVGGTGLADAMSIAPVASQIKDGEATPIVVV
                     DGKSDKLSKEAEDFLDDAQVDIIGGENSVSAKMEDYIDDATGKSPERISGADRQATNA
                     EVIKEYFDKDGVSNYFLAKDGSTKEDQLVDALAAAAVAGNYGSKHNEDGDITTDASPA
                     PIILATDNLSAEQHVAVSKTATTNGAKNLVQVGQGIADSVVSKLKDLLDM"
     gene            69722..72064
                     /gene="secA"
                     /locus_tag="KR231_000421"
     CDS             69722..72064
                     /gene="secA"
                     /locus_tag="KR231_000421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecA"
                     /protein_id="HBH0002838.1"
                     /translation="MSVLDVILDKTDELEIKKLNNIVDKIDALEDKIQILDDEALKNM
                     TNVFKDKLSKGETLDDILPEAFAVVREVSKRILGMRQYRVQLIGGIVLHQGKIAEMRT
                     GEGKTLVGVAPVYLNALTGKGVHVITVNDYLAQRDKELMQPVYEFLGLTVGVIINGQQ
                     PVERKLQYQCDITYGTNNEYGFDYLRDNMVTQKSEKVQRELNFAIVDEVDSILIDEAR
                     TPLIIAGGGDEGTKLYELANAFIKNIRDEDFEMDRKDKTIALTASGLSKAEKFFGIEN
                     ITHIDNIEIFHHVNQSLRAHKLMNIDVEYVVRDNEILIVDEFTGRIMDGRRFTDGLHQ
                     AIEAKEGVKINDESKTMATVTFQNFFRLYSKLSGMTGTAKTEESEFEATYKINVVQIP
                     TNKPVIRADLHDKVFKTERAKYNAVVEEIIRINKTKQPVLVGTVSIEKSEKLSKLLKK
                     KGVKHEVLNAKQHDKEAEIISKAGKLGSVTIATNMAGRGTDISLGAGDKEEEEKVKEL
                     GGLYVIGTERHETRRIDNQLRGRSGRQGDPGTSRFFVSLEDEVIKLYGGKSIEKILKR
                     MNANEDDALESKALNRAIERAQKGIEGKNFEQRKNVLKYDDTINEQRKVIYDERNKVL
                     DGSDIEEEIQKMVMDIITEAAEKYLKKFRDYHGYFKYLYNTFMPADTLLIPDLDKKNV
                     EEIVNQTYQISKRVYDLKKMMIGIEELAQLEKRVLLQVVDTYWVDHIDAMDQLRQYIG
                     LKSYAQKDPFKEYAIEGYEMFEALNRNIRITTVQYLYKFN"
     gene            72478..74349
                     /locus_tag="KR231_000422"
     CDS             72478..74349
                     /locus_tag="KR231_000422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding repeat-containing protein"
                     /protein_id="HBH0002839.1"
                     /translation="MNRKNLYVIMAAAMVSTSVAPSFAAEATQVKKQTITKKEATELV
                     SKVRELMAQRYTGGSQVGQPIYEIKVGETSSQLKIITNIDELEKLVNALGENKELLVT
                     IADKGHTTNSANEVVAEAIEKYENSADLSAEANSITEKAKTEATGIYGVATVEASYDS
                     TKDKLVITLKDKTDVVTSKTLQIGIGDEKVDLTANPVDIAGTNLDPSAEGFRVSKINK
                     LGVEGAKNIADIQLAEITIKNSDLNTVSPQDLYDGYRLTIRGNTIANSVGKSISDISS
                     KDSETGKYKFTVKYTDTSGKAIELTVESTNDKELKDVKDALNGNTKVNLIAGEDRYAT
                     AVAIAKETEYTDNIVIVNSNKLVDGLAATPLAQSKKAPILLASDNEIPKVTLDYIKEI
                     IKKSPSAKIYIVGGESAVSNTARKQLESVTKNVERLAGDDRHTTSVAVAKAMGSFKEA
                     FVVGAKGEADAMSIAAKAAELKAPIIVNGWNDLTADAIKLMDGKEIGIVGGSNNVPSQ
                     IENQLADIDKDRKVQRVEGETRHDTNAKVIETYYGKLDKLYIAKDGYGNNGMLVDALA
                     AGPLAAGKGPILLAKNDITNSQKNTLDKKLNLGAEVTQIGNGVELTVVQKIGKILGW"
     gene            74458..75165
                     /locus_tag="KR231_000423"
     CDS             74458..75165
                     /locus_tag="KR231_000423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PIG-L family deacetylase"
                     /protein_id="HBH0002840.1"
                     /translation="MIEATLFFSPHQDDETLSMGSAIIEHVERSDTHVILCTDGSKSI
                     IRKVLDDGGSCSYHIKDVHKYSLSESDFSKNRDEEFKNSCKAMGVKENNIHIENNRAH
                     DGELSKEKARDIMLKYLEKYPDAKVKTVTPYKALGIHEDHRALGEAALELYREGKIKD
                     LRFYVEPYDYNDFKKVNPNVRVWKVLSSQEEKLLNAMDAYKKWNPENGNYAIGYHSVK
                     SHFDELKSNKIQYVHAP"
     gene            75198..77330
                     /locus_tag="KR231_000424"
     CDS             75198..77330
                     /locus_tag="KR231_000424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding repeat-containing protein"
                     /protein_id="HBH0002841.1"
                     /translation="MKISKRIMSLLTATFFIFALSINIADASSKESLVGSGRWETAIK
                     ISQNGWKDATNAILVNDNSIADALSATPFAKLKDAPILLTQSDKLDSRTKAELKRLGV
                     KNVYLIGGMNTLSTNIEKQLKSENMTFERISGNSRYETSLKLAERLDKEKSISDIVVV
                     NGEKGLADAVSVGSAAAQENMPIILSDPNNGIKVANSFISSKNIKKSYIIGGTYSVSS
                     SIEQSLPNVKRLSGNNRNETNAKVLEEFYKNTDLKNAYITKDGMKKQGDLIDSLAVGV
                     LAAKNSSPVVLVGNSLDSSQYDVLNTKSFDNIVQVGGNGNEDAVKDILDLQEETIYRV
                     KTADELDVALRKADANDIITFKPDDNKKITSSFSIETKKAITVELEGLYTQTITVNMP
                     NGELTNKGTLDGTVKIMDIKNGTFINEGDINDIDIYDPNGCKIENKSGGDIWVLTISS
                     SAKDVNIENKGDISKVTNNSTSVIIRNSGNIDTLSGINAPAISGNKPRVDDTDKDEKR
                     ASGIYPTSEPLSPARAGYISVKIFTKPEDTNYKIYYRVVSSRPSALYIGDRIDTSDWT
                     AVPSSVLPFTIKAENGYYIEAVEINSDTKKVSRWGKSDYIDDGFYLKSETAKGLSADI
                     DFDGDYVKLTATGADSGCTVYYRIVSKKPVSMNVGDKVTISDWDEITTNRVRIEANDV
                     KDKYIELVELDDSTNKVTRWGASDKVVE"
     gene            complement(77383..77778)
                     /locus_tag="KR231_000425"
     CDS             complement(77383..77778)
                     /locus_tag="KR231_000425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GtrA family protein"
                     /protein_id="HBH0002842.1"
                     /translation="MILKKHRETILYLFFGAFTTLVNIVSYLFFTRVILFNFMVANAL
                     AWILAVLFAYVTNKFFVFESKRIELIFLFKEFLFFVSFRLLSGIIEMIIMYIMIDLFF
                     VNDITVKVFTNIIVIVLNYLFSKMIIFRK"
     gene            78005..80416
                     /locus_tag="KR231_000426"
     CDS             78005..80416
                     /locus_tag="KR231_000426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding cysteine protease Cwp84"
                     /protein_id="HBH0002843.1"
                     /translation="MRKYKSKNLSKLLALLTVCFLIVSTIPVSAENHKTLDGVETAEY
                     SESYLQYLEDVKNGDTAKYNGVIPFPHEMEGTTLRNKGRSSLPSAYKSSVAYNPMNLG
                     LTTPAKNQGSLNTCWSFSGMSTLEAYLKLKGYGTYDLSEEHLRWWATGGKYGWNLDDM
                     SGSSNVTAIGYLTAWAGPKLEKDIPYNLKSEAQGATKPSNMDTAPTQFNVTDVVRLNK
                     DKETVKNAIMQYGSVTSGYAHYSTYFNKDETAYNCTNKRAPLNHAVAIVGWDDNYSKD
                     NFASDVKPESNGAWLVKSSWGEFNSMKGFFWISYEDKTLLTDTDNYAMKSVSKPDSDK
                     KMYQLEYAGLSKIMSNKVTAANVFDFSRDSEKLDSVMFETDSVGAKYEVYYAPVVNGV
                     PQNNSMTKLASGTVSYSGYINVPTNSYSLPKGKGAIVVVIDNTANPNREKSTLAYETN
                     IDAYYLYEAKANLGESYILQNNKFEDINTYSEFSPCNFVIKAITKTSSGQATSGESLT
                     GADRYETAVKVSQKGWTSSQNAVLVNGDAIVDALTATPFTAAIDSPILLTGKDNLDSK
                     TKAELQRLGTKKVYLIGGENSLSKNVQTQLSNMGISVERISGSDRYKTSISLAQKLNS
                     IKSVSQVAVANGVNGLADAISVGAAAADNNMPIILTNEKSELQGADEFLNSSKITKSY
                     IIGGTATLSSNLESKLSNPTRLAGSNRNETNAKIIDKFYPSSDLKYAFVVKDGSKSQG
                     DLIDGLAVGALGAKTDSPVVLVGNKLDESQKNVLKSKKIETPIRVGGNGNENAFNELN
                     TLLGK"
     gene            80713..82290
                     /locus_tag="KR231_000427"
     CDS             80713..82290
                     /locus_tag="KR231_000427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp5"
                     /protein_id="HBH0002844.1"
                     /translation="MKAPKTILTILTIALTLSSISIIPSYALTEEKLIGNGRYETAVK
                     ISQKAYSSSPNVVLVNDNSLADALSATPFAKAKGAPILLTESDKLDDRTEKEIKRLGA
                     KDIYLIGGTAVLNKDIENKLKSNGLNVERINGKDRYETSLILANKLKDIKDIKEVAVV
                     NGEKGLSDAVSVGAPAAQNKMPIILSSPKDGVEAFDKFIRDEKVIKAYVIGGTNSVSR
                     AVEKSLPNAERVSGKDRNETNAKVIEKFYTDTNLSNLYVTKDGSKNENQLIDSLAVGV
                     LAAKNESPVVLVGNKLNTKQRDILSTKKLNTITQVGGNGNEEAFDEIKSLQEKTVFEA
                     KTVEELTDMINIASPNDIINFKPKENTVNEAFRMVTNKPITVNIKGDCSKTLTVDMPN
                     GEVNNYATLVNVIVRNIGEGGFNNHDTITILSVRDKNGRVIENTRNSDIDTLMILASA
                     NDTKLINDGYIGKLIDNSSNSDITNNGTIDKKVNQVEDLEAKVDSIEKAIDSISQKVN
                     KIQDILDKLGFLKKFLS"
BASE COUNT        32807 a         9373 c        14521 g        25796 t
ORIGIN      
        1 tataatagca aatttaaatt tattaaatag attaacttat aacatttcat ataaaatata
       61 ttgtgaatct gagaaaatta ctatttttct ttgagtattt tttgtaagca gttctaaaag
      121 attcaatttc atacctatta cttgaatcat tcatcaaaat aattctaatt taaaaaataa
      181 ttctatccaa ataatagata tataggacta tgttataata taaaaaaatt tatataaaag
      241 ttaataacta tacaagattg ataaagaaaa agtcaaaata gataattgat tagcaaaata
      301 gatataatta taatgaagtt aaatctagca atattctcct aaaattaaat ttcatttatt
      361 taattaaata taatttgaca atgggcaaaa aagtgagtaa aatataaata aaataaaaat
      421 aacaggttcg gataaagaaa aaggtttctt aacctcaagc ataaagtata ttatctaagt
      481 tatttgagat taagagataa atccaatctt aggtactgag gaggaaaaaa tgcttgatat
      541 aaaaagaata agagaaaatt tagattgtat aaaaaaagca atggaaagaa ggggcgaaaa
      601 aaactttaac cttgatgaag tagttaagtt agatgatgaa agaagaaaga ctcttcaaga
      661 agttgaagtt atgaaaaatg aattaaatac agcatctaaa aatataccaa atcttataaa
      721 agaaggtaaa gatgtagaaa atgaaaagat taaattaaaa gagttatctg ataaaattaa
      781 ggtaatagac caaaatctta aagaagtaga agataagatg gaatacctat taatgagaat
      841 accaaatgta ccacatccag aagtaccaca aggtgaaact gatgaagata atgttgaagt
      901 aagaacttgg ggaaagacta ctacctttga ttttgaatct aaggctcatt gggaaattgg
      961 aacagaatta ggtatacttg attttgaaac agctagtaaa ataactggtt caagatttac
     1021 tctttacaaa ggattaggtg ctagattaga gagagcatta ttaaattttt acttagacac
     1081 gaatacaaaa gtaaatggat atacagaagt tattccacca tttatggcaa atagaaatag
     1141 ttttttaggt acaggacagt tacctaagtt tgaagaagat atgtttaaaa tagaaggtat
     1201 ggactatttt atgattccaa catcagaagt tcctttaact aatatacatg ctaatgaaat
     1261 acttaaattt gaacaattac cgataaatta tacagcttat actccatgtt ttaggtcaga
     1321 agctggttct gctggaagag atacaagagg tttagtaaga cagcatcagt ttaacaaagt
     1381 agaaatggtt aaaatagttg caccagaaga atcttacaat gagttagaaa agcttactaa
     1441 caatgcggaa actatgctac aattattgaa tctgccttat agagtagtaa agatatgtac
     1501 aggtgattta ggatttacgg cttcttttaa atatgatgta gaagtttgga tgccaagtta
     1561 caataggtat gttgagattt catcttgttc aaactgcgaa gatttccaag ctagaagagc
     1621 aggaataaga tttaaaagag ataaagattc taaagctgaa tatgtacaca cattaaatgg
     1681 ctctgggtta gctattggaa gaagtgttgc agctatatta gaaaattatc aacaagaaga
     1741 tggttctgtg gttgttcctg aagttttaag accatatatg ggagtttctg ttattaaata
     1801 agagttaaat tatgtatttt taagtaatac aataatatag aggtaataaa aaataattaa
     1861 tataaaagtg atacaataat atagaagtaa taaaaaaata gttaatataa aagtgataca
     1921 ataatataga agtaataaaa aatagttaat gtaaaagtga tacaataata tagaagtaat
     1981 aaaaaaatag ttaatataaa agcgatacaa taataataga agtaataaaa aaaaataatt
     2041 aatataaaaa tgtgtacaaa ctaatgaata ttgatatagt aagctatcat atgaaagagt
     2101 atgtacacat tttttttact aatttttcac aatatgaaca taaataattt acaggaaagg
     2161 aatcttttat gaaaattcaa aatactgagt ggggatatat tgaatggaaa catacttatg
     2221 atgaaaataa tccaaaacaa gctatgaata tatacattgc agtaactatg cctggtaaga
     2281 aacattttaa tcatgttcat tatggtcaag agcagatgat atatatttta gagggagagg
     2341 gtttgtatat tataaatgga gtttggaagc cattttatca aggtatgatt ttttatatag
     2401 aatctggtag cacacatgaa actataaata caggcgatag agaaataaaa gaacttattg
     2461 tttcaaataa tgtagatgat gtaggagaga gtgaagttat agatattaat cctaataatt
     2521 atttaaagaa gaccttgata aattatagtg aaagtacatt aaatttgtat gcagcagtag
     2581 aatcaattcg tggtcaattt atagacccgt ttaaaattcc attaattata tatgatgatt
     2641 catggaatat agttttaaaa aatccttatt ttccactttt ttgttttgaa aaatgtaatc
     2701 ctatgaaatt tcctcaaaat tgtgattgta tgaatcaaaa aagtagcaat caatttgtat
     2761 gtgaatatgg gataactata tataatatac caatactgta caaaagcaat agcataggtg
     2821 ttataagagg agggtatgta ctattatctg atttgaattt agatacagag cataataatt
     2881 tatatgatat tccagaggga gctgctagaa gtataaaacg cctcttgaaa caaatatcta
     2941 aaaatataat aaatttttgc tcttttaatg atataagaaa ggatttacaa gaaaaagaga
     3001 agactatagc aagaacatat cattatggag agcaacttga aatgaattta aaagtagctc
     3061 aagatatggt tactaattta agaataaatc atcacttttt atttaataca ttaaattcaa
     3121 tggcaagcat agcactagat gatggtagtt atgatttgta tagtgcaata atagatttat
     3181 caagaatgtt tagatataca atgaggtctg atttaagatt tgtagaatta gaatctgaaa
     3241 tattatacat taaaaattat ttgaatttac agaaattacg ttatggagat gcacttaaag
     3301 taaaatatct tattccagag aagttatata acctttctgt gccttttaac tttattcaac
     3361 ctattgtaga gaatgcattt acacatggat ttagagatat tgacacagaa aagcgaattg
     3421 aaataattgc aagattagat tctcagtatg ccattataga gattcataat aatggaacta
     3481 tcttagatgg aaataatata gacaaaataa aggcaggtat tcgtagtaat aatggtcatg
     3541 gtttgtcttt aatatataca aaattcacat ctgcttatgg aaataatttt gatatggata
     3601 taaagtcgag tgataatgaa ggaacttaca taatgattaa aattcctatt gaaaattata
     3661 aggagtatgt atagaacttg tgaaaaatta ataagtttta taaatgttaa gaaatatatt
     3721 agatgttttt atgttgtttt atatatctta cttttttata ttattaagct aaaagggagg
     3781 tattctcatg agaagagcac taataataga tgatgaagaa gctgttctaa aaataataac
     3841 acattttata gaaatgaaag atatgccaat aaaaattgtt ggtaaagcaa catctggtga
     3901 tgaagcagta gataaaatca ttggtttaga gccagacata gtttttatag atattcaaat
     3961 gccaatatac aacgggttag aagtaataga aaaaacatct catttatcta aaaaaataaa
     4021 ctttgtagta ataactgcat ttaactattt tgaatatgct caaaaagctt tgagattaaa
     4081 tgtaaaagat atactcctta aaccattgga tatgaaagaa tttactaagt ctgtagaaaa
     4141 aattattgga tatcaatata ccaataatga tttattaaat gagatactgg aatatataaa
     4201 tctaaactat agcaatgact taaagttaaa tgattgtgct agattatttt taaccaatcc
     4261 atctaatata tctaggattt ttaaaagtaa tttaaataca acttttatat catatctaaa
     4321 tcatataaga atagaaaaat ctattgagtt acttgaaaat actacaaaaa gtataaatga
     4381 gattgcagaa atagttggat ataatagcct aaataacttt tataaaaact ttaagataga
     4441 aaaaggaatg actccaaaag tttataaact gaacactaaa aattgaaatt gataaataaa
     4501 aagtcaatat agataattgt ttgagtgtgt ctgaataagt atactttaat tatgataaaa
     4561 attaaagcgc tttaaacata tttaataata ttaaacctta taaaagctgt acctatttat
     4621 ataaaaaaat atatataaat aaaaagaaaa agatatacaa aataaaaaaa gtgaattaaa
     4681 tactgtttca aaaagacaga attttcattt aatttactga gagtttatat ttcttaaagg
     4741 aaggtaactt tataatggag gtaatttaat atgtcagaca aagtgaatat gaaaaatatt
     4801 atctgtattg caggcgctta tctagcaaca gcaattggtt ctgggtttgc tactggtcaa
     4861 gaaattctac aattttttgc ctcacaaggg tatatgggtt taattggagc attaatatca
     4921 atggtattgt tttcatttct tggtgctgaa gttataacta gaggtagaga attaaaactt
     4981 aaagaaccaa caagaattta cactttttat tgtgggaaga ttttaggaaa attttacgaa
     5041 tggtttagtc caatattttt atttgggatt cttatagtaa tgatttcagg tgcaggctca
     5101 actttaactg aatactatgg tataaatcct tacttaggaa gagtattgat ggctgttgct
     5161 actttaatta cagtgtctat gggtttagaa aaattagtaa gcatacttgg acgtattgga
     5221 ccagtgatag cagtatttac aattgctgtt ggattaataa gcttgtttaa gcattttgac
     5281 ggtttatcta tggttggaga agctatgaaa aatattgaag ttacaaaagc atcagaaagt
     5341 ccaatcgttt ctggtgtaat atataataca ttaaatatta ttgtaatgat tgttttttta
     5401 acaggaatgg gagcttctat tgaaagtaaa aaggatgctt tttggggagg tttattaggt
     5461 ggaatagtgt ttatgactgc tggtatagtt atgtatttgg ctatgatttc agatatagga
     5521 aatttgtata tgaaagaaat accatcactt tatttagcag ataatatatc tccgattgta
     5581 ggtgtatgtt tttcagttgc attaatatta ggtatctata caacagctgt tccactttta
     5641 tggtctgtaa ccaatagaat tgttgaagat gaacatccta aatttaaatt ggtaacaaca
     5701 gtaatagcta ttttggcttg tataggaggt tttttaccgt ttggtaaatt agtaaacatt
     5761 ttatatccat atacaggtta tatggggctt ttaattttag tctgtatggt gtataaagca
     5821 attacatgta gaaaaaaatc aacacaaagt caggaataga gccacttatt aatagttttt
     5881 atttaaaaaa attttttata taatccgaat ttaaaaagtc aaaatagtta aataaattgc
     5941 aaaacatgat aatatattta attaaaataa tatagtaaaa tataaatata aactaaaatt
     6001 aaatttataa aaaatatctt tataaagatt attaacttat ataatttgta gttaaattat
     6061 aaaaaataaa aaaataaaat tttggagagg tgttagtatg catgaactta ttttaatctc
     6121 agaaaagtat aaagaagata ttttagattt ttttacagat attcatatgc accccgaatt
     6181 aagttttaaa gaatttagga ctacaaaagc tataaaagat ttattagtga gtttagacat
     6241 agaaatatta gatttaggaa tggaaacagg cgttgttgga ttattaaaag ggaagtatga
     6301 tggtcccaca gtagcactaa gaggagatat tgatgcgttg ccaatatatg aagaggttga
     6361 tattaagtat aaatccagat atgatggtat aatgcatgca tgtgggcatg atatacacac
     6421 gtcttgcctt gtaggatgtg catatgtatt gtctcatatt agagatagtc ttcatggaaa
     6481 tgtaaagttt atatttcaac cagccgaaga agtcaataaa ggtgcgaaga tgttagtgga
     6541 acgaggagta atggaaaatc caaaagttga tgctatattt ggacttcata atcatccaga
     6601 tataccttgt ggaaaaatag gtgttaagtt aggtgggtta atggcagcag tagacactat
     6661 taagatagaa gtaaatggat ttggaggtca cggaggtata ccaaacagaa caatagaccc
     6721 tatagtagca tcaagtgcaa ttataatggg tattcaaacc atagtaagca gaaacataag
     6781 tccattagaa tcagctgtta tatcaatagg tactataaat ggagggactg caaataatgt
     6841 aatttcagaa aaggtagata tgacaggcac atgtagaagc tttagtaatg aagtacgaaa
     6901 gaaaatatca gaaaatttag aaaatatagt ttgtgagata gctcgtggat atcaagcaac
     6961 tgcaaagcta gattatttat ttgatttacc agctgttata aatagtaaag agatgtacgc
     7021 aatagcttgt aagtctgtgt gtgatttgta ttcagaagat gctatagttg atccaatacc
     7081 ttctacagga ggggaagatt tttctatatt catggaaaaa gccccaggat ttttttactg
     7141 gttaggggta ggcaacaaag aacaagattg tatatatcag tggcataatc ctaaatttaa
     7201 agctgataaa aattctatat tggtaggtac aaatgtacta tgtcagtctg ttataaatta
     7261 tatggataaa ttaaaaaata aaatttaaga tagagcattc tggagataaa gtttatgagg
     7321 gggtattagt ttgaggaaaa ttaattcaca ggaaaaaaac aaagatagtg gattattgat
     7381 gagggcacta aatgttgtag agagagcagg aaataaactt ccagacccag taaccatatt
     7441 tttattacta tgtataattg ttgtaatatt gtcagcagtt atatctaatt taggagtaga
     7501 agaaatacat ccttctacaa aagaagttgt aaaggtagta aatctactag agaaagagca
     7561 gattcaatca tatttaggta gcatagttac aaactttcag tcatttgctc ctttaggatt
     7621 agtactggtt acaatgcttg gagcaggtgt tgctgagaaa tctggattta tggaagtgtt
     7681 aatgaaaaag ggtataagta aagttccaca aaaacttgta actgtagcaa tcgtatttgc
     7741 aggtatgttg tcacatacag cagcagatgt aggatttata atattaccac cacttgcagc
     7801 acttgtgttt ttaggaattg gaagacatcc tcttgtaggt atgtttgcag cttttgcagg
     7861 tgttgcaggg ggatttgcag caaatgttat gcttagtact acagatgtat tgttagctgg
     7921 atttacaata ccagcagctc aaatgatgga cccatcttac caaggcaatc cagcaatgaa
     7981 tctttatttt gcttttatat cagcgatagt tttaactttt gcaggagcat ttgtaactga
     8041 aaaatttata gctcctcgtt ttacaaaata taatgattca acaaatgata aggatataca
     8101 ggaattgagt gaacttgaaa ataagggtat aaaatacgct ttattatcat tgttagttgt
     8161 agtagtagtg atagttgcct tatgtatagg tgacaatgca tttatgaaag atccagagac
     8221 tggttctata ctatctagta atgcaccttt aatgaaaggt atagttccta taatcactat
     8281 tatattttta actccaggat tagtgtatgg aaaagtaagt aagaagataa aaagtgacaa
     8341 agatttagta tctatgatgg gtagtagtat gagtgatatg ggtggatata tagtcctagc
     8401 atttatagca tcccagttta ttaatttatt taatcttagt aacttaggaa caattttatc
     8461 aataacagga gcaaaattac tagcagagtc gggaatacct agctatggat tgataatagg
     8521 atttatattg ctatctggat ttatcaattt atttgtagga agtgcttctg caaaatgggc
     8581 gattttagca cctatatttg ttcccatgtt tatgctacta gactttaatc cagcattaac
     8641 tcaaatagct tatcgtattg gagatgcttc aacaaatcca ataagtccac tttttccgta
     8701 ttttccagtt atattggcct ttgccagaag atatgataaa gatataggta taggtactgt
     8761 catatcgaat atgattccat actcagtggt atttacatta atagaaataa taatattgtt
     8821 actattcatg ggtattggca taccattagg acctggtgga ggaatatctt acgttttata
     8881 gaccgttata ataaatttat caatgaagat taaactaata aaatatattc tttaattaag
     8941 aggaggatta ttatgttaaa aacaacaaaa atttcagacc cagagttata caagattgta
     9001 gctgatgagt tggttagaca agaacacaat attgagatga tagcttctga aagtacagca
     9061 ccaacagaag tacttgaatt aagtggatgt gtatttacaa ataaaacaga agaaggctat
     9121 ccaggggctc gttttcaagc aggttctgaa gaagcagata aacttgaaac cctagcaata
     9181 aaacgtgcaa aagaagtatt tggagcagaa catgtaaacg tacaaccgta ttcaggttct
     9241 acagctaact attgtgtata ttcatcaata ttaaaaccaa atgacactgt tttaagtatg
     9301 cgtcttgacc aaggtggaca cttgacacat ggtagcgcag ttaatttttt acatgacatt
     9361 tataaatatg aattttatgg ggtagaccca aatactggac gtatagatta tgatgctctt
     9421 gaagcaaagg caaaagaatg tagaccaaaa cttataattg caggggcaag ttcatatcca
     9481 agattaatag attatgaaag aatatcaaag gttgcaaaag aagtaggagc ttactttatg
     9541 gtagatatgg cacatgttgc aggattagtc gcagcgaaag taatacctag tcctgtacct
     9601 tatgcagatt ttgtttcttc atctacgaca aagactttct gtggaccaag aagtggtatt
     9661 gtactttgta aagcagaaca tgcaaagaaa ctcgataaag gtgtttttcc aggaacatta
     9721 gggtctatac atcttaatac agttgcagca aaagcctttt cactattata tttaagtaca
     9781 gataaattta aaaagataat ggagcaagtt gtagtaaatg ctcagactct agcttctgaa
     9841 ctgatttcac atggttttag tattgtaagt ggaggtactg ataatcatat agtaatggtt
     9901 gacttaagaa gtaagaatct tacaggaaaa caatttgaaa aagctcttga atatgtagga
     9961 ataacagtta ataaaaatgt tatacctgac gacccacaat caccatttgt aactagtggt
    10021 gttcgtatag gtcttacatc aatatctcaa agaggtctga aagaaaaaga agttatacag
    10081 atagcaggga taatgaataa ggtagcagaa aatattgata ataaagaagt attagatgaa
    10141 tgtaaagcag aggcacaaga acttatatct aagtttccat tatatccaga agggtatttt
    10201 gaagattaaa tattttgatt tgtatagctc acaatttata aagcctgtaa cataaaattt
    10261 aataatatat aaccactata aggtgttgat taatcaacac cttatttttt ttgaaaagta
    10321 atatacaagc tatcataagc atataattcc ttatagataa ttaacaaggg ggataaagtt
    10381 atgaggtatt ataataaacc taccaaagaa gtattaaaat acttaaaaac aaatccagaa
    10441 attggacttg atgataatga ggtagaagaa aggaagctta gatatggatt aaatgaattt
    10501 actataaaag aaggtagaac attttgggac gagttgggag aaagtttgac agaacctatg
    10561 atattaattc tcataggagc agcagtaata agttcttttg tgggagaatt acatgacgca
    10621 ttaggtattt taggggctat ttttattgga atttctatag gcataataac tgaaggaaaa
    10681 tctaaaaaag cagctcatgc cctgtcaaaa ttaacagaaa atatagaagt aaaggtgctt
    10741 agaaatggga agataattaa aatatcaaaa aatgatttag taccaggaga tattgtatat
    10801 atagaaactg gggatatgat accagcagat ggaagactta tacagtctat aaatttgaaa
    10861 cttagagaag atatgctaac aggagaatct gatgatgtag ctaagaatgc tgatgctgta
    10921 ttagatatgg aagtagttta ttctaaaaca gaaataatcg aacaggatgc aatacctgca
    10981 aagcaagtca atatggtatt tggagggact cttgtagcat atggtagggg cataatggtt
    11041 gtcactcata ctggtgataa gacagagatg ggtaagatag cacagaattt atcaaatgaa
    11101 gaccagcaaa ctccacttca aattaaatta gggaagttgg gtgctaaaat agcgggaata
    11161 tcaggcgtaa tagctacttt attatgtatg tttatgatta tacagatgca gagaaaaggt
    11221 atgttaattt tagatacaag cagtgtatta tctttcttac aatcattaga acctgctaaa
    11281 aatgcatata tggtttgtat tgcattaata gttgcaactg ttccagaagg tttgccaact
    11341 atgataaata ttaccttagc tataacaatg caaaagatgg caaagataaa tgcattagta
    11401 acaaagaaag aagcctgtga aactataggt tctgtttctg taatatgttc cgacaaaaca
    11461 gggactttaa cacaaaacaa aatgatggta gaggtagcat atgttgatgg taaatatata
    11521 agtggaggag agtatcaaag taatagctat tttgaacaaa actgtatagt aaattcaact
    11581 gcagatatag aaaaagaaga taattcattt aaatatatag gaagcgcaac agagtgtgca
    11641 ttacttttat atcataatga taagaactat aatgaaatga gaaaacaaac gtatttgata
    11701 tcacaaatac catttagctc agaagaaaag aagatgtcaa cattaattcg tcaagaggat
    11761 tcagatatat tactttcaaa aggtgctcca gaagtattat taaaaaaatg ttcttatgta
    11821 caacaaggaa aaaatattgt tccaataact ccaaaagtag aaaaaagtat tttagatgag
    11881 attaagaagt tacaaattaa atctatgaga acattaggat ttgcttataa aaaaatgagt
    11941 aattctaaaa cagaagttgc aatgacttca gaaggtgaat tgaatttaat aggaaattca
    12001 agaagttata tgaaggaaga taatttagtt tttagtggat ttgtaggaat agtggaccca
    12061 ttgagagaag gggtcaaaga ttccattgat aaagcattta atgcaggagt agatgtaaaa
    12121 atgcttacag gagataatat aaatacagca acagctattg gaaatgaatt aggattatta
    12181 aatgatggga aaaaggcagt tgaagcaaca tatatagatg tattgacaga taaagaattg
    12241 agagaagaaa tcaaaggaat atctattgtt gcaagaagta aaccagatac aaaaatgaga
    12301 atagtttcag cacttcaaaa aagtggcgaa gttgtagctg taacaggtga tggtataaat
    12361 gatgccccag cacttagtca agcagatgtt ggaattgcaa tgggtatttc aggaacagaa
    12421 gtatctaaaa atgcagcaga tataatattg actgatgata gctttagtac tatagtagag
    12481 ggaataaaat ggggaagagg tatatatgag aactttcaaa gatttataca gtttcagctt
    12541 actgtaaata tagtagcatt tataattgct ataatatctc aacttactgg taaggatatg
    12601 ccatttacta caatacaatt attatgggta aatataataa tggatggtcc tccagcccta
    12661 gcattaggat tagaacctgt tagagattat gtattgaaaa gaaaaccaat aaatagacat
    12721 tctggaataa tagctaggtc tatgtttgta aatattatta taaatgctat tcttataatt
    12781 acaattgtat ttactcaatc agcttttaat atattgggag ctacatcaga agaacaaggt
    12841 actgttatat tttctttatt tgcattcagt gcccttttta atgcattaaa ttgtagagag
    12901 tttggtttaa atagtacaat accaaatttc tttaaaaata aactggcatt gcaaataata
    12961 gtagttacag ggataattca aataatattt acacaagtgt tccagagttt ctttaattct
    13021 gtttctttgg actttgatat gtggataaag ataatactat ttgcatccac tatcctattg
    13081 tcaaatgaat ttgtaaagct aattcttaga acaatgaaaa atagtagaac tatgaacttt
    13141 aatagtaaaa attaattcct atgaaaccgc aaagtactat atattgtaac tttgcggttt
    13201 ttgtttgttt aatgttgttt tatattacca ttttcatatt taatttttta ttaatctaaa
    13261 cacaatcttc cattgtaatt gcttcatctg tgtcaacaca ttcaaagtca atatctaatt
    13321 tttgtaatat tttgtatgcc tctttttgca aaggagtatc aaattcaata ggtgattttg
    13381 tgtaaatata actgataaaa aacatgattt atttcattcc tttccattta aaaacttata
    13441 gttatagtgt atcataaggt tataaaatat agataaatat agtataaatt taaaatatgt
    13501 acagacaaaa caaaaaaatc atattctaag taatacttgg gaaaaatgat attatcataa
    13561 taaataatct ttgtaaaaac ttatatagaa tctattaaac agacactaag ccataaaaac
    13621 tttactaaat ataaaattcg tatctaaata gatatataga ataatatttt actgaagtag
    13681 agtgattttt aagaatttta tatataaatt atgttatcat aaataaagat atagattata
    13741 aaatttgtta ataaaataaa gggcagggag gtaagtttca tgttttccaa aatcctagtc
    13801 aaaacattta tcagagatag cgaaaacgtt caaaatacag atgttagaaa taagtatggt
    13861 tatgtagctg gtgtagtagg tatattatcc aatttacttt tatttgtgat aaaggtattc
    13921 ataggaatgc tcacatctag tatagctata atggctgatg catttaataa tctttctgat
    13981 atggcatctt cagcaataac tatgataggt tttaaattag caagtaagcc agctgataaa
    14041 gaacaccctt ttggtcatgg aagaatagag tatttatcag cattaatagt agcatttatg
    14101 gtgatgttgg ttggacttca atttgtaaag tcatctatag aaaggatagt aaatccaatt
    14161 cctgtaaaat ttgaagtaat accacttata cttttaattg catctataat gattaaaatc
    14221 tggttgagtc gttttaataa atttatggga aataaaattg attcttcagc cttaaaagca
    14281 gtttcacttg atgctttagg agatgtattt acttcaagct gtgtagttat atcatttatt
    14341 gtagctagat ttactaattt tcctatagat ggatatgttg gtatcgtagt atcattagtg
    14401 atactttatg ctggtttctc tcttgtaaaa gatactataa atcctctttt aggggaagca
    14461 ccagatgaag aaatggtaaa ttctattata gagctattgt tatcttataa atatataata
    14521 ggtacacatg atttaattat tcataactat ggagttggta gatgtattgc atctatacat
    14581 gcagaaattc catccaacat agatataatg gaaatacatg aaattataga tactgcagag
    14641 agagaaatat ctgaaaaatt agatatatat ctagtaattc acatggaccc aatatgtctt
    14701 gaagataaag aagttatgtc agccaaaaaa gaacttgaag aaatacttaa gaaaaatagt
    14761 cttgtaaaat ctatgcatga ttttagaata gttggaaaag gaagcaagaa gaatttaata
    14821 tttgatatag tagttaatcc ttccgaattt tccaaaaaca tgtcagaaga tgacttaaaa
    14881 gaagatataa caaaattagt taaggagata aatcctgaat ataattgtgt aattgttgta
    14941 gataaggatt ttatttaatt attaattaat ctcatcataa ggtaaaaaat gtaaaaagga
    15001 tagacaatag tatagaggca taatataata gaagtatata attgtatttt taatataaat
    15061 aaagcaattt taattgtttt tatgaaatat tatagagatg ttgaagtata ttctattatt
    15121 gggcacctta tggatatact gagtcagtgg tgcaaccggc tatgaatata aatttattta
    15181 ttttcatagc tttttttgta taatttttta gtaaaaatta ctttatatac gatattaatg
    15241 gaagattaga ttataaatta taggtaacct aaaggggtga gatttacatg aagaaaggaa
    15301 atagaaaggc attattaatt agtttaatta tgattttaag tatggtggtg tctacaatat
    15361 atccaactgt atcttatgct tcagaattag gagagaatag tcagattcaa agtggttcaa
    15421 ctaattcatc aactggagag gagaaggaaa gcgacaataa aaagccagaa cagactccag
    15481 agaaagataa ggcaacagat aataaaaaac cagaacagac cccagaggaa gaaaaaccaa
    15541 cagataataa aaaaccagaa cagaccccag aagaagataa gtcaacagat aataaaaagc
    15601 cagagcaaac tccagaagga gaaaagccaa tagataataa aaagccagag cagataccag
    15661 aagaagataa gtcaacagat aataaaaagt cagaacaagc tttagaagat gaaaaaccac
    15721 tagacaataa aaatacagaa aaaactccag aggaagataa tctattagaa gatgaaaatt
    15781 tattgaaagt tttagaagaa gaacttaatg aagaaaatga agactatgga tttgttgtaa
    15841 aaattaataa caatacaata gaaacggaat caatgaaaaa aatatcattt aatttaactt
    15901 atactccaac atcaaaagga atacaagcag gagattcaat aacttttaag gtgccagatg
    15961 tattcaataa agttaattta gattatacaa gtgaatgctt tgataaaaca gaaagtaatg
    16021 gagagtatac acttacattt agagaattac ctaatggcca aagtgtaatg caaggtaaaa
    16081 taggtttgga agcatatgtt aaaaaggttg atgaagatac taatgcaaaa atacatattg
    16141 aaactactgg aaaaatagaa agtggaagtg gagatataga tgtagaaata aaacctggag
    16201 ataaaacgga tgttccagat gctaaaggaa cacttaaaaa gcttgttgaa ggaaaaaaat
    16261 caactactgt atttatgcca gttaaaaata aagatataaa ttacagtata caagtaaatg
    16321 aaaagcagga agagttaaaa gatattattt tgtatgatga gcttcctgaa ggattgacat
    16381 tgataaatgg ttctgtaagt gtagtaacaa gtgatggaaa agaagttagt gattttaata
    16441 ttgaacagag taaaaattct atttcagtta attttggaaa tatagataaa tcgtatactg
    16501 ttaagtataa ggctagaatc agtgacaaaa acgcaaaaca tggtaataaa tataagaatg
    16561 tagctaggat tgaatctgat ggtaagaaga tacaagaaga tgatgctact gtaagtatat
    16621 ttgatagagg agatgattat cttcttacta aaggacattc aggagcaaca aatattactc
    16681 aagttggtca agtaataaac tatcagattt caataaatga tgataaatca ccaataagta
    16741 atgttgttat aacagataat ataccagaag gcatgagatt aactacttca ggagaagctg
    16801 ggcatgattt tagagttgta gaaattccaa tgaatgggag ctggactcct tggagtaaag
    16861 aaaaaattgc caataatatt tcatataaag tagaagaaaa aagaaatgaa agtgggcaag
    16921 tagataaagt tataactgga tttacaatta atctcagtaa agaagaagtg gaatcaaagt
    16981 tttttatagc ttatacatta aaggtaatta gtattgaaga tagctatata aatagagctg
    17041 ttcttgatgc aaataatagt gaaattgata aaaatgatga gataaacttt aagaaaaatt
    17101 ctggattaat aagcgcaaaa aaagaagttg ataaaaaagt tttaaatagt agtgataacc
    17161 agattgttaa atacaaaatc aatatgtcaa cttatggagt ttatgatgca ggacaagtaa
    17221 atcttttaga tgaagtaaac tcagctctag aaatatctaa tataaaatat tctgataatc
    17281 ttgaacttaa aaaagaagct ggagatggaa aaaatacaat aagattagta aataaatacg
    17341 aatttaaaca gataaaagaa ggggaacctg tgcaaagttg ggttacattt gatgcagact
    17401 tcacaaatgt aaaagttggg gagactatac aaaatgtggc tcagattaat ggttcaagtc
    17461 ctccaggagt agagactact aagcaaggtt atgcttttga agctaaaaaa gtggatgctt
    17521 tagataaaaa tgtactttca ggtgctaagt tcaatttaga agatgcattt ggaaatatag
    17581 tagttaagga tttagttagt gatgaagatg gtataattca atctagtata aaaaaaccag
    17641 gaacatatta tttagtggag ataatggctc caagtggata tgaaaaactg aaggataaaa
    17701 ttaaggttga aattggtaat aaagatattg gtagaatagt ggatattgga aatatagaaa
    17761 acataagaca agaaaatcca ccagtaaatc caccagcacc accaaataca gatgaaccaa
    17821 tagtaaatcc accagtacca ccaagcacag ataaaccaag gaaaccatca agttcatctg
    17881 atacagagga tactatagtt ataaatccac caataccacc atcagaagat ataataaatc
    17941 cgccaatacc agaggtattg aatccgccag taccaccatc agaagagatg atagaaactc
    18001 ctgttaaaca gattattcca ataccagaag tagtaaagcc atcagtgtca gaagaaaaaa
    18061 ataataaagt taaagatgat actttggtaa atccaccagt accaccaaaa acaggggata
    18121 gtactacaat tattggagaa atacttttgg ttataggagc tattgtagga cttatcgtat
    18181 taagaagaaa taaaaataca aattagaccc taacattata aaaaatataa gttatattaa
    18241 aaaatatctt ctaaaacaat atttaataat gaaaatattg ttagaagata tttttttttg
    18301 aagatttatg taaaaaaata ataacttttt agaaaaaagt tccaaaggga tatagacaat
    18361 taaaaagata taagctataa tatagatata aaattaaatg aggcaaaact agggaaacct
    18421 agtcacgcaa agctataggg gctaaagttt agtaaaccat gccagccagt tgccgaaaag
    18481 agtaaaaatt tctttttgta tatacaaaga tactcttggg tatctttttt attttgaaat
    18541 ttattactcc cggcctaact caaaggaggg aataatatga gaccaagtaa aaaattatta
    18601 atagctataa tatcaatatt cttaataagt tcagttccag taagtgcaca tgcagatagt
    18661 actactatac aacaaaataa agacacactt agtcaaatag tagtttttcc aactggaaat
    18721 tacgataaaa acgaagctaa tgctatggta aatagattag ctaatataga tggaaagtat
    18781 ttaaatgcat taaagcaaaa taacttaaaa ataaaattat taagtggaaa gttaacagat
    18841 gaaaaagaat atgcttattt aaaaggtgta gttcctaagg gatgggaagg tactggaaaa
    18901 acttgggatg atgttccagg tttaggtgga agtacagtag ctcttagaat aggatttagt
    18961 aacaaaggta aagggcatga tgcaataaat ttagaattac atgaaacagc acatgcaata
    19021 gaccatatag tattaaatga tatatctaaa tcagcacaat tcaaacaaat atttgctaaa
    19081 gaaggtcgtt ctttaggtaa tgtaaactac ttaggtgtat atgcagaaga attttttgca
    19141 gaatcatttg catattacta tttaaatcaa gatacaaata gtaagttaaa atcagcttgt
    19201 ccacaaactt atagcttttt gcaaaattta gctaaataga gttttaataa atttaaaata
    19261 aatataaata aagagatgct attataatag catctctttt atattgcgtt taaatctaat
    19321 aaattttgtc ttatgtataa ctatgataga ttatcaatta ctactcctta tacaaggctt
    19381 caacgtgttt attatgcatt tgagtaatta tcgtaggtat aatagaaatt attgaaccaa
    19441 ttactatcaa taaaattcct ataaccatgt ttatagggat aatttcttta agtattaata
    19501 atgctagtat tggagatatt actggtttaa agaagaatac taaagatgta agactagtag
    19561 atgtagcttc cattgccata aagtaaagcg cataaccaac acctgtaaca aatacgaata
    19621 cataaatcat aatgggcata ttgtgtaagg tatatccact aaaaataggg atatttgcaa
    19681 atacatgaag cttattttta tttaatatat ctgcgataaa attaatttta gtgagtaaaa
    19741 ccaatatcaa catttccaaa ctaccaaata taaagctaaa gcaggttaca actattccac
    19801 caaattttaa ggtttttctt ttaccaaata cagtatacat tgaaaaaata atagcagaag
    19861 ataatgttaa gaatattcca ctaagagtta gttttgtatg caatggattt attataacta
    19921 taattccaag aacttctaat ataagtgaaa ttacattgtg cctatatatt ttttccttca
    19981 aaattaagta agctaaaagc attacaaaga ctggattaca actgaacaaa acagcaacta
    20041 cagatgcctt tgtgtttaga acagcaagtt gatacaatga catacttact actacacaca
    20101 taaaacctaa aaatgcaaag tattttaagt ctgattttgt aatagaaaga ctaagagctc
    20161 ttaatctttt tacagcaaaa ggtagtaaga ctaaaccgcc aacaaaaaat cttgataaag
    20221 ttatttgtaa gggattaaag tcattagtga cagtttttag actaatttcc attgaactaa
    20281 aaaataaggt agtcagtatt atataaacat aacctttttt caagtcaaac acctccttgt
    20341 aatttatatt agtactatag ataagaatat tcaagcatat tggaataata tggtatgtat
    20401 aaaatatagt acataaaatt ataaactacc ttaatataga atgtaagtat tctatactaa
    20461 ggtagttaat tatttgaatt actttgattt agttatttta aattatataa tttggctaat
    20521 ttttcaaatg ctggtaaaga acttttaact ttatcataag atacacaata tgatactcta
    20581 aaatgacctg gacaaccaaa agaagaacct ggtactaata ataaattaaa ttgttttgca
    20641 tcattgcaga attttttatc atcttcaatt ggagcttttg ggaacaaata gaatgtacca
    20701 ttaggtttaa cacaagaata tcccatatcg attaaactat tatatagaag gtcaaaattc
    20761 tttttataaa tatttacatc aacttctgca tctaaacttc ttgcaataac cctttgaaaa
    20821 agagaaggag catttacaaa tccaagtatt ctatttgcaa catttaatga agacataaca
    20881 tcatcaaaat catccatttg cccattagca acaatatatc ctatacgttc accaggtaga
    20941 gataatgatt tactataaga gtatcctata aatgaatttc tatagtattt tagtacacaa
    21001 ggaactttgg caccatcata aattatttct ctatatggct catcagaaat taggtatatg
    21061 cttgtattaa attctttttg ttttgaatcc aataattctc caagattttt taataattct
    21121 tcagaatata tgacaccagt aggattattt ggagtgttta ttattaaagc tcttgttttt
    21181 ggagtaatag cattttttag agcatctaaa tctggctcaa aagtctctat atttgtagga
    21241 acttctatta attttccatc atagttttct gtataatttt tatactcacc aaaatacggt
    21301 gcaaaagcaa taacttcatc accaggattt aaaagagttt ttaaaataat atttagacca
    21361 ccagcagcac cacaagtcat aattaaattt tctcttgtaa gatttaatcc atctttttta
    21421 tttatgtgtt cagcaatagc atctcttaca tcctcatatc ctgagttgtt catatatcca
    21481 tgaactaaat ttggagattc ttcatttaaa atatcattta taactgcttt aatagtctct
    21541 ggaggttcaa cacttggatt tcctatacta aaatcaaaaa cattttcctc accataaata
    21601 tcagaaagtt tctttccttc ttcaaacata gctcttataa cagaactatt tgcaactaaa
    21661 gtttgcattt tattagatat catatgtaac actccttttt atagatttat attgcttatg
    21721 tatatattac catattttta ctgaatttag acaattttcg aaaaattact tgtttgaaaa
    21781 tataaacttt tatataaaat atatttatgt acagtacata ttaaaaattc caatttctaa
    21841 ttttatcatg attattttat ataatagttt tttaaagaat taataaaaca tagatttaga
    21901 gaataaaata ttcttgacta tattaattgt ttaatataat atagttgata tagtcaaaca
    21961 tattataatt atagaaggga aatttaagat ggattttaaa aatttacagt atgaaagttt
    22021 gtcatatatt atttgtaact tgcaaaaaaa ctttaaactt tattgtgaaa aatgtttaaa
    22081 accatataaa cttacgaatg gtctatattt ctatttaatt tatattaata aaaataggaa
    22141 ttgttctttg aatgatgttt ctacagaatt tgaagttgat aaagctcata caacaagaac
    22201 tatatctagg ttagaacaag atggatacat agaaaaaatc caaaacccta atgatagtag
    22261 agcttttcag ttgagagtaa cagataaggg tgaggaagta ttaggggata taaaaaacat
    22321 attttcaaag tgggataatc acataaaaaa agagttctcg gatacagaat ataaggaact
    22381 ggtaaagaat ttacatgtgg taaaggatat aaaaacagct gtggaggaag aataggatgt
    22441 attgtaattt attaaaacca attaaaattg gaaatttgga attaaaaaat agagtatctt
    22501 ttgcacctac aagcatgggt cttaaattgg aagaaaaaat taaaaagttt tctgatattg
    22561 ctaagtcagg agtagctctg attactctag gagatgtatc tattagacct agttttcata
    22621 aggtagctat aagcctatcg gatgaagatg gagtcatgaa atacaagaaa attgtagatg
    22681 aaatacacaa ttctggtgca aaggtatcag cacaactatt ttgttcagat tatgatgtta
    22741 atttaattaa agatactatg aatatgggaa ttacttcaca tgatgagata aaaaaaataa
    22801 tgaatgacgg agtaaaagat tacataacaa atatgcccaa agaagaaatt aaaaatatta
    22861 taaatttatt taaagtaaca gcattgaatg caaaaaaagc aggttttgac atgattcaaa
    22921 ttcatggtga taggcttgta ggaagttttt catcaagtat atttaataat agaaatgatg
    22981 aatatggtag aacgtgtgat aatagaagta gatttgcaag cgaaataatt agtagtatcc
    23041 gagatgaagt taaggacatt ccaatagact ataaatttgc aataagacaa gaaaatcctc
    23101 attatggaaa tgcaggagtt ttactttcgg aagttgagta ttttgttaaa aaatttgaat
    23161 ccctaggtgt aaacagtttt catgtaacac ttgcaaatca ttcaaaatta gaagatacta
    23221 taccaaccaa taatcatcct tactttaaag aagaaggctg ttttttatat ttagctgatg
    23281 aagtaaagaa acacacaaat cttccagtat gtggggttgg aaaattgtct agcccagatt
    23341 ttatagaaag tattatttca aataatagag tagatatggt ttctatgtca agacaattac
    23401 tagcagatag gaattggtta cagaaagtaa aagatggaag agtagatgag attaaaaagt
    23461 gctgttattg taataagaag tgtgcagatg ctttacaaac acgctctcag tttggatgta
    23521 tactagatta gaatatcctt ataaaaataa ataatttgtt aaggttaata tatttttggt
    23581 gatttagata agtatttaga taaagaggag gagacatcat gaaaagttta gttttatatt
    23641 caagtttaac tggaaatact aaaaagattg cttatactat atatgatgaa attcaagaag
    23701 aaaaagacat taaagatgta aatgaattag ttgattatag tattgactat gaaaattatg
    23761 atatagtatt cttaggctat tgggtggaca agggaatttg tgataaaaat tcaaaacaag
    23821 tgcttgaaaa tattcacaat aaaaagatag cactatttgg aacaatggga gcaagtaaaa
    23881 aaggaagtta tggagctagt ataatagaaa agatagaatc aattatccca aaagataatg
    23941 aaatattagg ttcattcata tgtcaaggta agatagcaga aggattgaaa gcaaaatata
    24001 aagagatgtt aaaactttct cctgacaacg aacatattcg ccaacaatta aataaccatg
    24061 aggaatctca aagtcatcca gatgaacaag aaatatatga agccagtatg tttgcaaaaa
    24121 atatgatgat taaagctagt attgtgtagt agttaaacaa taagttcata taagatatag
    24181 aataaataat ttagtaaaaa agtatagcaa ataatttgct atgctttttt tatgaaatca
    24241 aaaaaataat aaaaatactt gactgtaaac cttgtttata cattatttta tagaaaataa
    24301 gatagtttta aatataaaaa aagatatatt attgaaagga gatattattg tatgaaaact
    24361 tataaaagat aattagtttg attttaagat atactaaata tacaatttta tagagtgaaa
    24421 atatttaaga ctatattata gttataaatt aatagaatag agaggtagtg tttaaattgc
    24481 aataacagta tttccaaagt tgccacctca aattcctatc caatggaata atggtgtagc
    24541 taattatgta gataaaaaat ttatttatgc ctaccctgtc atttgtgttg tattcagaat
    24601 ccttttacgt ccatttatat ggagatggtt acaaatacat gctttttata gtgacactat
    24661 tgcagattat ttaacgaatt ttatgtgttt tgtagcgttg tctatagaaa tattctctat
    24721 actttttatt tacaatattg ccagacatgt tacaataatt atttttatag atatacttgt
    24781 atttattgct ttactgataa taggtatgta taaattattt aaaaaataca attaattttt
    24841 aaaaattaag taataagtga tagtgtaaaa agtagccact gcaaattatg gattgtagtg
    24901 gctattttat tatttgtata tgaaattatt ttgtttttct aataagttac gatatattat
    24961 ggtttatttc actgataaaa ggtttaggta ttttaaagta aaaagttgta tattctaata
    25021 aaatttaaac attttgattc tttaaaatta gagaaaatac attgttctta ttaaaaaatt
    25081 aaatattaag aatttaattt ctgcatctta tttagaaaag ataagaaatc aactttatat
    25141 atttttttgg gccttcctct ttgattatcg agttttgtat ttacaatagt tgcaattcct
    25201 gctttatata agatactcaa tattctatta gcacttctaa gagttatgtt catatagttt
    25261 gataatattt ctgctgacac attatttgaa tttctatcat taatcataca catgatttta
    25321 gatacatttg tattagatag aggtataaaa gaagcaactt tattggctat tgagctatct
    25381 tcaatattat tagaattttt atttgaatat aaagggccta ttgtatcatt agtatcattt
    25441 actataaaag tacagtttcc attcaaagaa gcagatttac cattagcttg acgagcattt
    25501 tgctctgcat gaatatttgt atttccaatg ccccaaccta tatttaagct atatttaatt
    25561 tcttttaaat cttctgaaat aaaaaaatct gtatagttat tggtcatatt gtttaacatt
    25621 tctttagtag tgtgtatctc tattttcata tcattttttt tgacctgaac tccataaaat
    25681 ccatgtcttg atagagaatt taatatagtg ttatatattt gattttgtat ctcatcattt
    25741 ttaaatatca aatcttcatt tatgtactct gaactattta ctgtaactat acaagttgca
    25801 gatttatttt tgtctaagtt ttgtaatgtt atttcattca ccagagattt aaatgtattc
    25861 aggattgatt ctgtagatgg aaccatgtaa atacaatcat atccaagttt attaagttca
    25921 caactaatga tgtaatttct agtaaaagaa aggttaatct tattatctcg caataagtct
    25981 aaatgtattt ccaataattt atcatttaat tttttaaagt catatacagg ttgagggata
    26041 ttaaaatctt taattgtata tggacattta ttagagtcta ttaatgaata tatatcataa
    26101 taattgttgt cctctcttaa aaaatccata aatgattttg taaagtcaat atctttttgg
    26161 ctatttaata atttgaataa gtatttataa aaatctcttt catcaagctt taaaaaattt
    26221 aatggaactt ttatgtcttt tatatttatt ataagttcac tatatggaac tataccactg
    26281 catacaaatc catcaaaatt atctacttgc tcatagtata tattaggtaa attattaaaa
    26341 ggattctccc ctttgagctc aataaatgta atttcacaag tatcatttaa ttctttaaga
    26401 gcttgtttaa acttatctga cataaaataa gatgttgtca aaaaaccaat tttatatttc
    26461 ataaaacctc ctttaaaatt tcgagagtat agtaactaat caatcaattt ataacctcat
    26521 tttataatag tagataaaac gcgtcaattt attttacaaa aggaaaattt aaagaaaaat
    26581 cagaaaatat aaaaaagact gaaaaatatg ttgactgtca agaataattg tgctattttg
    26641 taattaagga ctagtctttt aagatttcct aaaataaact tagattttag gaaagaaata
    26701 cattttattt gaaaataaag gagaagatta tgaatacata tttaaatgaa atttctaagt
    26761 ttgttgatga gaatagagaa gaaatagttt cattatggaa agagattgtt aatatagaaa
    26821 gctatacaca ttgtaaagaa agcgtaaata aattggctaa gagattaaag tttgagtttg
    26881 aaaaagaagg tttagattgc gagttagtag atgttggaga taatggtagt acattgatag
    26941 gtacacttgg ttctaatata aataaaaagc ctataatttt ttcaggtcac atggatactg
    27001 tctttgaaac aggtacattt ggagagaatc catttaaaat aatagaagga aaagcatatg
    27061 gcccaggtgt tttagatatg aagggtggta taataatttc cttatatgtt attaaagcat
    27121 taaataaaat aggatacaaa gaaagaccaa taaaaatagt attttctgga gatgaagaga
    27181 taggacataa ggattcaaca ggtgcagatg ttatattgag ggaagcaaaa ggtggtcttt
    27241 gtgcttttaa tatggaaact ggattagtag ataatagttt gtgtgtaggt agaaaaggaa
    27301 gaataggatg taatatacat gtaaaaggtg tagaaacaca cgcaggtaat gattttgaag
    27361 gtggaagaaa tgctatagaa gaaatggcta ataagatact acgcatacaa aaattgacta
    27421 atttagatgt tggaactaca gtaagtgtaa gtgtgattaa gggtggaaga gtggaaaatt
    27481 ctattccaga agattgtagt ataaaagtag accttagatt tgaaaaagta gaagaaatgg
    27541 agaatgttaa agaacaagtt agagagatat gtaaagaaac ttacatagaa ggaacttcta
    27601 cagaagttaa ttttataagt gaaatgatgc catttgaaac tacagaagat gttatgagat
    27661 ttcatacatt tgtaaatgaa gtgtcaaaag aaaatggatt tggagaatta aatgctaaga
    27721 gacttggagg tagttcagat gctagttatt tgactattgc aaacgttccc gcaatctgtt
    27781 catttggtgt aagaggggaa tggaaccaca catcaagaga atatgcagta gtagattcta
    27841 tgtttgagag ggtgaaatta atttctacag ttattttaaa cttagataaa tttgaggtat
    27901 aaagggggat tttatatgga tgtaacagct ggagataata aggtaacatg gaaagggtat
    27961 ttatctttat ttgtattgat agtattattt tcaggagtgt ttaaagatag tcaaggcttc
    28021 cttaaagcat tagattttgc taatctgaca ggttcatttg gtactattgc agatggtgta
    28081 gactttatgg gtaaaggagg aacgggagca aaagatggtt tcttatttgc tctgactttg
    28141 attccaactg tctgttttgc tgtaggtctt atagatgtag ttgaatctat gggaggaatg
    28201 aaagcggcat caaagatatt taatccattg cttagacctc tgcttggtat acctggaata
    28261 gcaggaatag catttgtatc ttcatttact agttcagatg tagcctcaat aatgacgaaa
    28321 gaattatttg aaagtgggga aataacagat gatgaaagaa ctatatttgt agcatatcaa
    28381 tatgctggtt cagctgttat actgaacaca ataaatactc aagctccact tttaccaata
    28441 gcattattgg cattaggtcc aataatcctt atagagatat tctgtaaaat acttggtgct
    28501 aatctagtta gattaatcat aggtgtaaga aataaaaaga ataaggctaa ggaggctgtg
    28561 tagtatgagt caacaaaata ctggaaatgc aattgtaaat agtaaaccta agaaaactgc
    28621 tgttgagata tttatggggg gagcaaaaaa aggtttttac ataggtgttg aacagatatt
    28681 accagccatg ataatgggtt atgtaatagt gcagttttta caattaactg gtttagttga
    28741 tattttagga aatatttttg gaccagtaat gggtattttt ggactacctg gggaatctgt
    28801 tttagttttg atagcagcat tctttgctaa ggcagcagga gcagctacag ctgcaaactt
    28861 atttgcacaa ggtctaatca ctgcaccaca agcaaccata ttaattatgc catgtatgtt
    28921 aatgggtact ctagttggtc attatgccag aatagtgctt gtagcaaatg ccagtactaa
    28981 gtatagaatg ttactgttgg cagttcctat atttgatgca atagtgggga tgttaatagt
    29041 aagagtttta ctcactgtta tgggattaat gtaaataaca taaaattata acctaactat
    29101 aaatgatata taagaattaa tatatacaag gattaatgag tagtaattga tatatagtaa
    29161 taaactaaga tagtaattaa tgtgtatatt aattaaaaaa agagagtatc tcaaagtgaa
    29221 ctttttagtt catgagatac tctttttgta tgaaatcaag tatattttca taatttcaac
    29281 aatgaaagag aggcttatct ctattttgag acagcctctt cttttaaatt tatatttcta
    29341 gaatttatgt tttttattta tccaacatta acattagtta ttagaaataa ttttaagaaa
    29401 aatatacttt catgttaata tcagaataaa tctgttttta aaggatgatt tgttttgaat
    29461 tttcacgaat atctacttct atgacttttt ctattgtatc tcctctaaaa cctaataaat
    29521 tacttgtcaa gtttgcagtg gaacaagaat gattaggtat aattcttatt ctatcaccaa
    29581 tttttatatc agtttcacca tttactttaa tttttccaac ttcttctgaa agtgaatcaa
    29641 tagtaagttc tggatgtcca cataccctac cataaccaac aatactacta tttccatgtg
    29701 cacctttatc aagtccaagg cacttacttc cacaatcaat taaatagtat ccactgctat
    29761 tttttgagat tacagtgcac acaacagtaa gagcacacat atcttcagta gcacaaccta
    29821 aacctatctg tatagcatca tagtatacat agtttccagg tcttacagca gttatagttt
    29881 tagaagcagc ttcagattca actgttggag tactaccaga agcgacaatt tctatattaa
    29941 atccattatc agttagagct ttgtatgctt tctccataga agaatcttct tgaacacaaa
    30001 catctggaac accttctgga gaactacaac catacacttg acctggatgc gaacttatac
    30061 caacaatctt tatgttttct agcttagaaa tttcagtagc aagttcaacc actttctctg
    30121 gttcaacccc aaaacggtgt aagccacaat ctacaataat aagtagcttg cactctattt
    30181 ttgatttaga aaaagcttca ctataagcct tagcacattc tatattatct gtagcacaga
    30241 ttaaatttat ttttgatgcc atagtcacaa ttctatttat atttacttct cccatgtaag
    30301 gataagccaa cataatatct tcaaaacctg cttttatcag agcttcacct tcatcaagtg
    30361 ttccaactag aaaaccacta gcacctgcat ttttttgaag tctcgctatg taagtacttt
    30421 tatgtgtctt aagcataggc caaagttgtt tattattatt tgtacaaatt tgttgaattt
    30481 tatctatatt cttttctaac tggtctaaat ctagcaaaaa atttggagta gcgacttctg
    30541 aaattttcat gttatttacc acctttcaac aaaagtaaat taactataag tattataatt
    30601 attatattag taatatcgtc tttataatat taatagctta taattatatt atagaactag
    30661 cgttaacaga gagcaatatt tatttgtaat aattagaatt ttcaataagt tagtgtggtt
    30721 ttaaattatt tatataatat atttttaatt ttatgcaaag tttatttaaa ttagtttgag
    30781 gatttattaa tagggtatta ttgaatgagt aaaaaagtga tgtttacata gaataatcac
    30841 actataaatt aatttagaac ctaaaaaatt aattgagcaa attggaaaag agaaggataa
    30901 aaaagatatt tggatagttg gtggaggcga tatagtaaaa ttatttatga aagataactt
    30961 aattgatgat tattatatat atatattgcc aataatattg gggagaggga tttcactatt
    31021 taagtctggt atagataaga ctaatttgaa ttttaagaaa gctagtaata ttggagaact
    31081 tgtaaaattg gaatacagta aaaaacaaaa ataaattaca tgccaatttg ttacaatgtt
    31141 atgaaatgaa gcatttaaaa gacttttggc tatatgaatt gacattactt gtcaaatatg
    31201 ttaacatata agcgacttgt cggagggtgt attaaaaaga atatgctgga gaagagagtg
    31261 cgttaactct tttctccttt ttttataaaa ttaagcattt ataaatttag tattattaca
    31321 tgattacact atctcaaaaa ttaagaaagg agaaaaatat gaaattaatt ttaagttatt
    31381 taaagaatta taagttatta atagtattaa acatactggc tatatttagt tttgcattag
    31441 tcgagttggg gattccaact ataatagcta aaataattga caatggtatt gcaaatcaga
    31501 atatagctta cataaaacaa atgggaatag tgattgttat tatttctatt ataggggttg
    31561 taggtagtat attgttgggt tattgttctg ctaaggtatc aacaagtgta accagagata
    31621 taagaaatga catatttgag aaatcacaag aattttcaca tactgaatac aataaatttg
    31681 gaatttcttc aatgattaca agaacaacga atgatgcatt tcaaattcaa caatttgtta
    31741 atatactact aaggactgcc ttattaactc cagttatgtt cattataagt ataataatga
    31801 caattagaac aagtgtggaa ctttctatag tattggctat atcagtacct tttataatta
    31861 ttggagtagc aataatagca aaagtatctc aggcaatatc ttcaaaacaa caaaaaggac
    31921 tagataaatt aaaccttata tcgagagaaa atttaactgg aataagagta attagagctt
    31981 ttggaaatga tgattatgaa acagagcgat ttgaaaaaac aaatacatat tatgctaatg
    32041 tttctaagaa actatttaag cttatgtcaa ttactcaacc agcattcttt ttactattaa
    32101 atatagctgt tttggctgta ttttggattt caagtgagaa gataaatatt ggagagcttc
    32161 aagttggaca gttggttgca tttttggaat atcttttcca tgccatgttt tcaattatgc
    32221 ttttttcaat ggtatttatt atgtatccaa gagcagaggt atctgcaaat agaataaaag
    32281 aacttttaaa tgaagaacca ttgataaaaa atcctgaaaa tggaattaag gatactgaaa
    32341 ataagggtat catagaattt gataatgtaa cttttaccta tccagatgga gaagcttctg
    32401 tacttaagga tatttcattt actgcaaaaa caggtgaaac agttgctttt ataggaagta
    32461 ctggtagtgg gaaaagtact ctaattaact tgatacctag attttatgat gtaacagaag
    32521 gtagtattaa gataaatgga gtagatataa gagaatatga tttaaaagct ttaagaaaaa
    32581 agataggatt catacctcaa aaatcactgc tttttactgg tagcatagca aataatatta
    32641 gatttgggaa acataaggca ggagagtcag aattagaata ttccgcaaaa gttgcacaag
    32701 catatgagtt tatatcaaaa aaacctagaa agtttgatga attgattagt gaaggtggag
    32761 caaatgtatc aggaggtcaa aaacaaagac tttctattgc aagggctatt ataagaagac
    32821 ctgaaatata catttttgat gatagttttt ctgcacttga ctttaaaact gatgcaatac
    32881 ttcgtgctaa attgaagaag gaaacaaaag atgcaattgt attgattgtt gcccagagaa
    32941 ttagttctat tattgatgct gataagatta tagtactcaa tgaaggacaa gttgtaggaa
    33001 tgggaactca taaagaatta ttaaaaaact gtgaaatata ctatgaaatt gcaacatctc
    33061 agttaaaaaa ggaggaatta gaataatgaa aaagtctaaa ggttttaaga aaacaattgg
    33121 tagacttctt ccatttgtaa agaaatataa attttccttt attatagcta ttatatgtat
    33181 aatttcagca gctactatga atgcacttgc acctaaaact gaaggattga taataacaca
    33241 attgactaaa gatgtaatta gtatcgcaaa aggagtacca ggggcttccg taaattttga
    33301 ttatgtaaca aaaatattgg tgattttagc atgtatatat tttgccaatg caatttttac
    33361 gtatacttca agttttctac ttaccaatgc tattcaaaac acaatgagag atttaagaaa
    33421 tgaagtcgaa aataaaataa gaagattgcc tattagttat tttgatagta atagttttgg
    33481 agatgtatta agtcgtatat caaatgatgt agatacaata tcaaatgcat tgcagcagag
    33541 ttttatgcaa attgtaaact caatcttagt cataattttg gcactttcaa tgatgtttac
    33601 aattaatata tatatggctc ttatagctct ttttataatt ccaattagtt attttgtatc
    33661 taaatttgta gtaaaaaaat ctcaaagtag attttcattg caacaaaatg ctcttggaaa
    33721 attaaatggg aaagtacaag aaatgtatac tggatttaat gaaataaaac tatatggtaa
    33781 agaagaagat tctataaaag aatttaaaaa agtaaatcaa gaactttgtg aaaatggatt
    33841 taaggcacaa tttatatcaa gtatgatgaa tcctatggtt tcattagtaa cttactttgg
    33901 aattgcagct gtggcagttg tcggttctat atatgcagta agtggaggaa taacagtagg
    33961 aaatttacaa gcatttgtgc gttatatatg gcagataaat cagccacttt cacaaatgac
    34021 tcagttatct acagtaatac aatcttcttt tgcagctata gaacgtgtat ttgaaatttt
    34081 agacgaagaa gaggaaatac ctgatgttga aaatccagtt aagatagaaa atgtaaaagg
    34141 aaatgttaca tttgagcatg ttaattttgg atatggagaa aattcaactt taatagaaga
    34201 tttaaatgca gaagtaaaaa gtggtcagat ggtagctatt gttggaccta ctggagcagg
    34261 taaaacaaca ttaataaact tattgatgag gttttatgat gtaaagaaag gtgctattaa
    34321 aattgatgga gtagatataa gagatatgaa acgtaaagat ttgcgttcaa tgtttggtat
    34381 ggtgcttcaa gatacatggt tatttaatgg aaccattttt gaaaatatag aatatggtag
    34441 atttggagct actaaagaag aaattataca agcagcaaaa gtagcaaatg ttcatcactt
    34501 tataaccact cttccagatg gatacaatat gtttttaaat gaagaagcat ctaatatatc
    34561 tctaggggaa aaacagcttt taaccatagc tagagctttt atatcagacc cttcaatatt
    34621 gatacttgat gaagctacga gttctgttga tactaggctg gaacttatgc ttcaaaaagc
    34681 aatgagaaat cttatgaatg gtagaactag ttttgttata gcacatagac tttctacaat
    34741 tcgcaatgct gacttgattt tagttatgaa taatggaagt attatagagc aggggaatca
    34801 tgatgaatta atggaaaagg gtggatttta tgagaagctt tataatagcc aatttgcaga
    34861 caaagaatca gaatagataa cataaacttt tgtataaaat tttgtatcaa attcaaatat
    34921 taatcatata attaaaaaga gtatcagtaa gttgtttttt tatagattta ctgatactct
    34981 ttgattttaa gaccaaaggt acttatgatt ggtacttata attcacaact agtcttgtta
    35041 catctgataa ccagaattac agtacttttc ttttttacct ttttgttctc taacatataa
    35101 caattcgctt aacttatcaa tgtaataacc atcatcactt atgcgaatta aactagtcag
    35161 ataatatcca tctttgcttc taggaatctt tttatttatt gctaaatcaa tagctgtctt
    35221 tgctgcttca aaatgcttta aatgtgtatg accttcttca aaactctttc tagtattata
    35281 aactacataa ccttttttaa cttgaaaaac tataaattct ttcttttcat atattttatt
    35341 aaacattcaa tcagcccttc tcaagatagt tttatagcat aacattagaa gcttctaaaa
    35401 aattttacaa agaacataaa tattttataa attataaatc taaaactata atttataaag
    35461 ataactttct gattatttat atgataattc atatagatta aaagtaaatt atctttaggt
    35521 taaacaaaag taaaataaaa gactagttat aatatttata tgaaaaagta caaaatatag
    35581 tatatgaata tagaaaattt aaattattta tttacagttt ttatttccat aagtatattt
    35641 accttcagat accttgtcat catggaaata tattctttca caacttttat ctccccatag
    35701 aatgtttttt gttattttat gggacgtatc tcctgtaaat acttcagcta cagtagtatc
    35761 tgtaacatca cagtaaagag aagcgaattt tttaaaccaa ggattttcct caaatcttaa
    35821 aagccaggaa gctccatagg ggcaatgtaa ctcttcaaat tcaggaaccc atcctagaaa
    35881 tggaacatca gttgtgctaa taatattgtc tgcaattaat tcatctccat tttcatgagc
    35941 tctctctctc atagcaatag ctctttcttc agacctttca aataaaactt ttcttaatat
    36001 ttcgctagtt ttatcttcac caaactcttc aaataacact ttggaaaaat aaaaatataa
    36061 atcaccaaaa tgtttgcatg ccatacgaac ttcttcaata gcataatctt tgtcaatagt
    36121 ttcattagtt acaacatctt cgttcaaaaa aatcactcct tagaataagt attagttaca
    36181 atataattat agaatatttt ttataaatta ggaaattaat ttgagataga tatattttta
    36241 ataaatgaaa gtataatgct aaaataactt attgttacaa aaatcttcta aattaatgta
    36301 tttaggagtt tccatatgaa tgagagtagt tctgtaaata tcttcaatac atccatttgc
    36361 aatattatta aaaatatctg tgtgctcttt taatgttgtt tcaagccttc cttcatgtga
    36421 caatgaatcg agagctaatt tttttattct gtacatataa ttgttaaaca ttttgtcaaa
    36481 ttcagtattt tgagcatatg aaactatagt tgtgtgaaat aatgtatcgt attctgcaaa
    36541 tgagtttaaa tttttatcac ctaataaaat atctttttgt ttatctaaaa gatgttttaa
    36601 tttacttata gtttctactg ctctagcttc tttgtattga cttgtaatta aaaaagtaca
    36661 aaatccttct attgcagagc gtatttggaa tatctctaca atttcatttg ctgtaatttg
    36721 atggattcta aatcctttgc ttgggattat atctataaat ccatcttgac taagtctttg
    36781 aagagcatct cttataggtg ttctagagat acctatttca ctagcaagtt ttgtttcaga
    36841 atatatttca ttttctatca tttctccaga tagtatcaat tcttttaagt agtcatatgc
    36901 ttgttcttgt aatcttttaa atgtagccat acttaataat acccccctaa acaatataaa
    36961 aatacaaaaa cttatataat tttaagcata caacatagtg aaaataaggt caatcttttg
    37021 caatttaaat tgcagataag attaaaaaat ataaaaaatt attgaagtgt gaagcatgat
    37081 taacattaaa ggcagattaa ttaaaactaa ttgaaattag ttaaaataca aaactgtaaa
    37141 agtagtatat tatatttgaa aacaatagta tgtattaaaa cttatatagg atgactaaat
    37201 ataataaatg actttaaaaa ttactattta ttgttaaaat aaatactttt atattttata
    37261 ttgaccggta tactggtatg tagtatactc taaaacataa aaaacgtttt caaaaatgtg
    37321 aagatatgga gggttataaa atgaaattgg gatttattgg attaggaata atgggaaagc
    37381 caatggcaaa aaatttatta aaagatggat gtaatctttt ggtgtatgac attaataaat
    37441 ctgctgtgga tgaacttata tcatgtggag caaaatacgc aagtgtttta gaaatgggtc
    37501 aagaatgtga tattgtattt acaatccttc caaatggaac tattgtgcag gatatattgt
    37561 ttgggatgga tggattggca aaaactttaa aagaaggaag tatagtagtc gatatgagtt
    37621 cagttactcc tacagaatcc atattgtgtg caaataaatt aaaagatatg ggcttagaat
    37681 ttatagactc accagtaagt ggaggggagc caaaagcgat tgatggtaca cttgctttta
    37741 tggctggtgg taaggaagaa atttataaga aagtagaacc attttttaat ataatgggaa
    37801 gctcatctat tttaattgga gataatggta gtggaagtgt tacaaaactt acaaaccaag
    37861 taattgttaa tttgacgata gcagcagttt ctgaggcatt tgtacttgca gcaaaagcag
    37921 gtgcagaccc agaaaaagta tataaggcaa taagaggagg cctagctggt agtacaatat
    37981 tggatgcgaa gataccaatg attatgaatc gtgattttaa accaggtggg aaaatatcta
    38041 ttaatttgaa agatattaag aatgtaatgc aaacagcaca caatttagat gtaccactac
    38101 ctatgacaag tcaattatta gaaattatgc agacattaaa agtacatgga catttggaag
    38161 atgaccatag tggaatagca cagtattttg aaaagttggc aggtgttgaa ataaaaaaac
    38221 acaataatta atatttaaat atatcaatat aattaaatac atattattag gattagatta
    38281 tataaataca gcgaggttaa gttatcatag taaaagaaaa ataaaattga taaataataa
    38341 agtagaatga taaaggggta aagattatga ttacaggata tggacttttg atagcatttg
    38401 ttatatctat aggaatttta cttgtatcga ttattaaatt taaagtaaat ccgtttttgg
    38461 cattactgat aacatctata attacaggct ttatggttag aatgcctata aatgaaatat
    38521 caaccacaat atcgactgga tttggaaata cattaggtag tataggtatt gtaattggac
    38581 ttggaataat atttggaaat attctttcag aatcaagagc aacagaatct attgcaaagg
    38641 ggttgttagc taagactgga gaaaaaaaca gtgctttagc agtaactaca gcaggttttt
    38701 taatttcaat tccagttttt atggatgcag cttttgttat aatgatgcct ataattaagt
    38761 atgtttcgag agtaactaag aaatctctaa tggtttttgt atgtgcctta ggagttggga
    38821 ctatagtagg tcatgcactt gtaataccta caccaggacc tttagcagtt gcagcaaatg
    38881 taaatgcaaa tgtaggtagt tttatacttt attctataat tgttgctttt ccagcagctc
    38941 ttataggtgg atggatttat ggaaaacgtt ttgaaaaata tccagcttat gctattgatg
    39001 agaatgatag agaaaaaaat ttagagcagg gaaaagatag cataaaaatt gaagatgatg
    39061 attcttctaa agtaccaggt tttggaattt ctatgttttc tttattgttc ccaatacttc
    39121 ttatacttat atcaaatgta tttagtatgt tcttagaaaa aggttctaca atgagtggag
    39181 tacttgcatt tataggagat aaaaacatag caatacttct tggaatattg gtggcaatag
    39241 gatttttaaa gaaatacata aataaaccta tgggagatgt agttattgaa gctgctgatt
    39301 cagcagggct aatattattg ataacagggt caggtggtgc gtttggcagt gttataaatg
    39361 caagtggtat aggtaacttc ttagttgata ctatgtctgg tcttagtata tcagttgtag
    39421 tgcttggatt cttattaagt gccttgctta gaatttctca aggttctgct actgtagcct
    39481 tagtaacaac atcatcaatt ttaggaccta caattttggc aactggaatg tcaccagttt
    39541 tagtagggct tgctatatgt gctggaggag ttggtttctc ccttccaaat gattctggat
    39601 tctgggtact ttcaagattt agtggattat cagttaaaga tactttaaac tcttggacaa
    39661 ttggaggaac cattgctgga gttgtagcat ttataatggt tttattgctt agtgttataa
    39721 atggaattat accacttcca ggtctataaa taacaaacta ttgtttatat catataaatt
    39781 acatttagac tatacaaatt acataaaggg gcgttttaaa tgagagaagt aaaaccaatt
    39841 agcatagata tacttaatac ttttaaacaa gtagatgagg acagattaaa taaacttctt
    39901 gcagatgagc ttaagcattt agatagaaaa attgttgtat tagatgatga cccaacaggt
    39961 gtacaaacag ttcatgatat ttctgtttat actgattggg ataaggatag tatggaacaa
    40021 ggttttaatg agaaaaatag tatgtttttt atacttacca attcaagggg atttactgtt
    40081 gctcaaacta caaaagcaca taaagaaatt tcaaagaata ttgtggatgt atcaaagaaa
    40141 gttaataagg attttataat cataagtcgt agtgattcta ctatgagagg acattatcct
    40201 cttgaaacta atttattaaa aagcgaagta gagagattat cggagaagtt atttcagggt
    40261 gaaataataa tgccattttt taaagaaggt ggtaggttta ctatagataa tgtacattat
    40321 gttaaagaag gagaaatact tgtaccagca ggaatgactg aatttgcaaa agataaatct
    40381 tttggatata aatcatctga tataggtgag tggtgtgaag aaaagacaaa tggaaagtac
    40441 aaatctagtg atatgatata tatttcgtca aaagaactta gagagctaaa tattgaagct
    40501 ataacagaaa aacttaaaaa agctgaagga ttcaataaaa ttattgtaaa tgcaaccgat
    40561 tatgtagatg taaaggtatt tacaattgcg tttatacgag cagtaaatag tggtaaggaa
    40621 tttatgttta gaagcgctgc tgccataaca aaaatacttg gcggagtgag tgacaaggaa
    40681 ctacttacta aggatgaatt agtatcaaaa ggtaatacca atggaggaat tatacttgtt
    40741 ggttcacatg tgaataagac tacccaacag ttagaagaac ttaaaaattg taaatatccg
    40801 atagaattta tagaatttaa tcaacattta gttcttcaag aaaatggtct aaaaaatgag
    40861 gtaaaaagag ttataaaagt tgtagaggaa aaaataagca ggggtaaaac tgttgctgtt
    40921 tatactagac gagagcgttt tgacttggat acgaatgata aagataaaca gcttatgatt
    40981 tctgtagaaa tatcagatgc agttaccagt ataattggta tgcttaatgt aagaccaaat
    41041 tttattatag ctaagggtgg aattacttct agtgatgttg gtactaaagc actaagagta
    41101 aaaaaagcta cagtaatggg acagataaaa cctggtatac cagtatggat gacaggcaaa
    41161 gaaagcaaat ttcctaatat gccatatata attttccctg gaaatgtggg agagattagc
    41221 acacttagag aatcagttga gatattgatg gggtagtata ttagtgtatt gaagtttaaa
    41281 cgcttaaatt tactgagtta aaattaaaat aaactaaaat tataaattaa gattaaaaat
    41341 aatagtatat taattagggt ttagagtatt ttacaaaaaa tattctaaac cttaatctta
    41401 tgtattagta tttttattat ttaacttatg tgtttatttt attatttatc ttttttaatt
    41461 gatttaatat tttctttgat tttatttaaa atatctgtat gcttattaga gcttatgttg
    41521 gggaatgctt tgattatacg tctatgaagt aatttgtggt tagacagcaa agtattaagt
    41581 ttatttttta gctcatcaat acgattttta gcatagcgat aattttcttt ttctttaagt
    41641 atttcaaacc tatcttccaa agtatccagt ctattttcaa ctaaagattc aagtttgttt
    41701 tctatagttt cttgtgtaat aagtttgtag tattctttct tatcttttaa ttccttaatt
    41761 ataagattga tttgttttaa cttaccattt aattgtaaaa ttgtatggac tgtgataact
    41821 aaatctaaaa caaaataaat ttctatagat atagcaaata taaatagcac atttttagag
    41881 atagagttaa taaagtcaac cacaatagga tgtactataa gcattacaat caatgataat
    41941 acaccaaaca taagtgagtt ttccagacaa actcttccgt gaatattaaa tttatgttta
    42001 gaataatccc accaagtcat attaaatatt ttttctaaaa taaagctcgt acaatactcc
    42061 attatgctag ttataattat actaaacaaa aacaacaaag gaatagtgtg tacaaaagga
    42121 gtcaaggtag caactattgc taatgctcca aatccatata tagggcaaaa tggaccattt
    42181 aaaaaacctc tatttacaaa ttgtttttgt aaaactgaac aatatgtagt ttcacaacac
    42241 catcctataa agctataaat tacaaaataa agaaattgaa tataaaatgt actcataagc
    42301 acctcatttc tagttagtat aacactatat actcgatatt ttatttttat gattaattta
    42361 ctaaattcaa tttacatatt gattatacca atttatagaa atttatcaaa tttaattaca
    42421 gttagaacat tataaacatg gttataataa tgaaatttta tttaaaataa ataagggtgt
    42481 caagtataat caaactaata gttgtagata ctctacacta tgttagttta attacatttg
    42541 acacccttat atttatacta tgactattta cattcgaaac tagagcaaca tgtttcaata
    42601 taaaggttta ctctatcagt ttcaggagca accaatatat tatcaagtgt acataagcta
    42661 ccatctttgt tgtatttaca attttttaca gtacaaacta attcctcaca atttctatta
    42721 ttaacgttgc tagataaatt actataaata gattcatcta aaaatgaact acaacaagta
    42781 tgtctgtcat tgtgagcttt ttcaccattt ataaaaattt tatctgcata acatatatgg
    42841 ctgttgttat gtgaacagtt aattacatta cagtttattc tttccaaagt tattacctcc
    42901 taaacgatta tttattataa attatgtcca tataattaca agaatataac cattaagaga
    42961 aaactacctt ttagaaaata tctattctta gagtaatttg aaatataaat atattttctt
    43021 ctaaaattta cctaaattgt ataaaaactt acagcttgga gaaaataata gaaaaaggag
    43081 gcgtaatcaa tgtttgaaaa gaagaaaaaa gaattatttc cttggaaaat atctgcctta
    43141 atactggttg gagtatttgt attaagtagc ggagtttata tagggacaag attaaaacac
    43201 aatggagttc aaactggtga agttgtaagt actagtgcga atatgaatga aaagtcaaaa
    43261 gaagcttttg gattaaataa aaattgtgaa gtttggcttc aaagtgaagg cgaaaatgaa
    43321 actaactata agagaacact tacaatggca ggaatagttc cagagtcatt attagataag
    43381 acgaagtcag aaatagtatc atattttaaa aaagaatatc caactaaaaa aataaagagt
    43441 atggataaaa atgaaatcat attggtagaa tctaaatata gtgataataa agatgtacaa
    43501 gcaatggatg ttactataaa aggtaaatat actattgaaa atgataatgg aaatatagca
    43561 ctatataaat atgatgatag tggaagcaaa acattagtag aaaaaacaaa aataagagta
    43621 gattcacttc ctaaaacagt tcaagatgaa atcaaaaaag gtgtagttat ggatactgaa
    43681 gaagaggcct attcaagatt agaagacttt gcaagttaat agtaaattaa tattatttta
    43741 agttaaatac taagtaagtt aaatactaag taaattaata ataaataatt taatattaaa
    43801 tagattagta ttaaatagat tagtattaaa attgtagtca catttaattc ctataaaaat
    43861 acaataattt atttgtaata aatataaaag ttatattgag gtaaaatctt gctttgatat
    43921 aactttttta tttgatttta tattttacat agagcatttt atgatttgtt aatattattt
    43981 atgatataat gatttagaac ataagttttt atgagaaata cattttggta tttcttttat
    44041 ttttaggggg aattttaaaa aatgataata ttggggattg acccaggtat agccatagtt
    44101 ggatatggta taattgaata caaaaatagc aagtttaaag taatcgatta tggagcagtt
    44161 acaacacctg cccatatgaa tatatcgaga agattggaac ttgtgtataa aggaattgat
    44221 acaatagtaa agaattacaa tatagatgaa gttggaatgg aagaattatt ctttaacaag
    44281 aatgtaaaaa cagctataac agttgcacaa gctagaggtg ttactatgct tgcatgtgct
    44341 cataatggga agcctgtata tgaatacact ccacttcaag taaaacaagg tgtagttgga
    44401 tatgggagag cagataaggc acaagttcaa cagatggtaa cttcattttt aagtctaaaa
    44461 aaagttccaa aaccagatga tgttgcagat gctttagctg tggctatttg ccatgctcat
    44521 tcaaacaaac ttgaaaaaac tctaaagaat ataggtggta agtatgtata gttatataaa
    44581 aggtacagta gaagaaattt atatagacag tatagttgtt gaaaataatg ggataggata
    44641 taaaataaat gtatcatcca atacaataat gaatttacaa gtgggagaag ccacaaaaat
    44701 atatactaaa ttaattgtaa gagaagatga tatgagtctt tgtggttttg taagtaggga
    44761 agaacttaag atgtttgaat tactaacatc tgtatctaaa ataggaccta aagtggcgct
    44821 ttcaatacta tcatttgcat caccagcaca gttaggagca tatattttaa gtgaagacat
    44881 tggaaaatta tccaaagctc ctggtgttgg taaaaagaca gcagaaagaa tcgtcttaga
    44941 gcttaaggat aaggtagaca aaaataacat agagtttgaa ccaacattat tatcacaaaa
    45001 acctaccttg atatcacaag atgagtctgt agatgcactt gtagctttag gctatacttt
    45061 gtcggaatca aaagaggcag ttcaaaaatg taaaaaagat ggtatgaata cagaagctat
    45121 tataaagaaa gcacttacat atataatgag taaatccttg aaatagtatt tggattttat
    45181 aatatttgga ttttaaaaca atatttaagg agtttatgta aatttgaaaa tatataaagt
    45241 agattttcaa aagtatgaga ggaggggtat aaatgcaagg ttttgaagat gaaaatagga
    45301 taataacttc tacaatgaag atggaagata tagatataga aaatagttta agaccaaaaa
    45361 ctttagaaga ttatttgggt caagaaaaat ccaaagaaca acttagtata tttatagaag
    45421 cagctaaatc tagaaatgag cagttagacc atgtgctttt atatggacca ccaggtcttg
    45481 gaaaaactac actagcaagt ataatagcaa atgagatggg ggtaaattta agaattacgt
    45541 caggacctgc aatagaaaga gctggagatt tggcagccat acttacgaat ttaaatgaaa
    45601 atgatgtttt atttatagat gagattcata gaatcaatag aagtgttgaa gaagttttat
    45661 atccagcaat ggaggatttt tgcctagata taataatagg gaaagggcca tctgctagaa
    45721 gcataagact tgaccttcct aaatttacac ttattggagc tactacaaga gctggtatgc
    45781 ttacaaatcc acttagagat agatttggtg ttatttgtaa attggactat tatacagttg
    45841 atgaactttc aaaaatagta cttaggtctt caagcatctt agatgcagag atacagtcta
    45901 atggagcatt agaacttgca aaacgttcaa gagggactcc aaggatagca aatagattac
    45961 taaaaagagt tagagatttt gcacaagtca gagctgatgg aaaaataact gataaggtgg
    46021 caaaagatgc tctggaactt ttaggagtcg atagtttggg tctcgatttt gtagatgaga
    46081 agcttcttat gactataata gaaaaattta gaggaggacc agtgggttta gatacattgg
    46141 cagcttctat cggagaagat agaaatacaa tagaagatgt atatgagcca tatttgcttc
    46201 aattaggatt tataaataga ggtcctagag gaagagtagc tatgccatta gcatatgaac
    46261 acttaaaaat tccatatcct aatgaaaaat aaaaatagat tatacgagta tttataaaat
    46321 aaaagagtca ttaaattaaa atatttctaa aatggctaaa aattcaaaca tatccacaaa
    46381 atggtaatta tatctgtaga tactgtggat aaacacgata aaaattgtgt gtattgtatc
    46441 tatatattgt ggataagaca tgtatatcgt ggaaaaatat ctatatattg tggatatggt
    46501 gtctgttaaa aatagcaatt tcttgataga ttatggtaat attgtggaaa ataagttgtt
    46561 tttttgatat tattgtagct ggagaaattt taagagagga agtttaacat tgaaaacaag
    46621 tgattttaaa tttgacttac cacaggaact tatagctcaa gttcctatag aagatagagc
    46681 tagctcaaga ttgatggtat tagataaaga gacaggtaat attgaacata aagtatttag
    46741 agatataata gaatatttaa atccaggaga ttgcttagta ttaaataata ctagagttat
    46801 accagctaga ttaataggag agaagcttga aactggaggt aaaatagagt ttttattatt
    46861 aaaaagaaca gaggaagata cttggcaggc tttagtaaaa ccaggaaaaa gagcaaaagt
    46921 agggactaaa ttttcttttg gaaatggaaa gctaattgga gaagttgtag atttatcaga
    46981 tgaaggttca agaattataa aattccatta tgatggaatt tttgaagaaa tattggatga
    47041 acttggaaat atgccactac ctccatatat cactgctaga ctagatgaaa aagaaagata
    47101 ccagactgtt tattcaaagc ataatggttc agcagcagca cctacagcag gattacattt
    47161 tacagaagaa ttgttaaata aaataaaaga aaaaggtgta gatatagcct ttgtaactct
    47221 acatgttggc ttaggaactt ttagaccagt aaaagtagag gatgttttaa atcacaagat
    47281 gcattcagaa tattatatgg ttagccaaga agcagctgac aaaataaata gagcaaagga
    47341 aaatggaaaa aatgtaatat gtgttggtac taccagttgt agaactatag aatcagcttg
    47401 taatgagtat ggaaagatga aagaaactag tggatggaca gaaatattta tatatccagg
    47461 ttataaattt aaagttttag ataaacttat tactaatttt cacttaccag agtctacact
    47521 aataatgtta gtaagtgcta tttgtggaaa ggataatgtt ttaaatgcat ataatgaggc
    47581 agtaaaagaa agatatagat tcttcagttt tggagatgct atgattataa agtagggagg
    47641 taatggatgc atagtttaca aaaacaaaaa aagaataacc ctatattaaa gattgctttt
    47701 atatttgaac gtgttttagc agtagtagtt ctaatagcag tatttttagg aactatagat
    47761 gttctaagac ttatgtgggg agcatatata gttgattttc aaaatccagt acaatacagt
    47821 cagcttaatg attttttagc acaaatatta cttttagtaa taggtgttga acttgtagta
    47881 atgctatctc ttcatatacc aggagcattt attgaggcat tactttacgc aattgctaga
    47941 aaaatgttgc tactgcctaa aaatgaaggt atgatagatg ttttaatagg agttatagct
    48001 atagcaggac tatttgctat aaaaaagttt ttagtaacaa aagacaagag tgctcttaat
    48061 ataatgagta ttcatgatga agaagcaatt aaggaacaac agaacaaaga agacgaagat
    48121 aaatctattt agacaataaa ttatatgaat agcttattac aaatatatct taagaaataa
    48181 tgagaaataa atatgattaa ggagaacttt atgtacgcag taagatacga attgataaag
    48241 acttgtaagc agagtggtgc aaggttagga agattacaca ctccacatgg gattattgaa
    48301 acaccaatat tcatgccagt tggaactcaa gcaactgtaa aatctatgac accagaagaa
    48361 ttaaaagaga ttggttcaca aataatactt agtaacacat accatttata tatgagacca
    48421 ggtcatgaac ttataaaaag agctggtggt cttcataagt ttatgaattg ggataaacca
    48481 atacttacag atagtggagg gttccaggta tttagtctag ggcctttaag aaagataaaa
    48541 gaagaaggtg tagaatttag gtcacactta gatggttcaa aacattttct aactccagaa
    48601 aaagctatgg aaatacaaaa tgcattgggt tcagacataa tgatggcatt tgatgagtgt
    48661 gcaccatacc catcagatag agaatatgta aaaaattctt tagaaagaac aacaagatgg
    48721 ttaaaaagat gtaaagatgc ccataataat accgacaagc aagctttatt tggtataata
    48781 caaggtggga tgtataaaga cttaagggaa caatcagcga aagaaataac taatattgat
    48841 ttaccaggat atgctattgg tggacttagt gttggagaac caaaaccact tatgtatgac
    48901 gtgttagagc atacaactcc acttatgcca aaggataaac caagatacct aatgggagtt
    48961 ggtagtccag atgacttagt agaaggtgtt ataagaggag tagacatgtt tgattgtgtt
    49021 ctacctactc gtatcgctag aaatggaact gcaatgacta gccaaggtaa agtagtagtt
    49081 agaaatgcaa cttatgctga agactttact ccacttgacc ctgaatgtga ttgttatgct
    49141 tgtaaaaact attcaagagc ttatataaga caccttataa aagcaaatga aatactgggt
    49201 gcaagattaa taactactca taatcttcac tttttattaa atttaatgaa acaaataaga
    49261 caagcgataa tggaagatag attacttgat tttagaaatg aattttttgc aaaatatgga
    49321 tatgaaatat aggttttgca ctattaatta taatcatttt aatatataat attcaatagt
    49381 actcaaagat agagaaagta aattgttata taaacattta ttatgattta caaaagagta
    49441 taatttacaa aggagtgaaa aattaatgcc acagcaacaa ataattatga gtataggtct
    49501 atgggtagta gtaatcgcaa tcttttattt cctaatgatt agacctcaaa agaaaaaaga
    49561 caaacaatta aaagaaatga gaagcagcct aagtgtagga gacaaggtca ttacaatagg
    49621 tggaatagta gctaatgtag ctaaagttga agatgatgtt gtaatattag aattaggacc
    49681 aaatagaact aaagttccat ttgaaaaatg ggctatagga actgttaaat ctaaaaaaga
    49741 agaaatagaa gaagactaaa ttagtaattt aaaagccttt tctcgaatat atattaattt
    49801 gagaggaggt ttttttatgg gaaaatctaa ttatattttt aaaggtctag gatatgcata
    49861 tataataact ttggctgttt tattagtgta taacttattt ttgacattta cagatattgg
    49921 tggagataat ataactatgg tctcatcatt tataactact atttctgcag ctataggagg
    49981 gttttacact tcaaaacaca tgaaagaaaa aggacttatg tatgggcttt tagtaggact
    50041 tttgtacata gtatgtattt ttttgactgt gtttttagca caagaaaagt ttgtatttga
    50101 aatagggatg atttataagt tattgctaat atcagcagca ggaggcattg gaggcgtatt
    50161 gggtgtcaac tttaaataga gtttatatta aagtagtttt atgatataat caataggaaa
    50221 caattagaaa tggaggcgtt gaaaatggaa aataaacatg taaaaacttt atctcaagct
    50281 actttaaagc aaagtgctgc aaaaggtgga tgtggagagt gtcaaacttc ttgtcaatca
    50341 gcttgtaaaa cttcttgtac agttgcaaat caagagtgtg aaagatagaa aattattgat
    50401 ttagttgttt gtaagagggt atctcaaagt gattctttta tcattatgag gtatcctctt
    50461 ttattttcaa ttattatata aaaatatata ttctatttat gtagaagtaa atttgatttc
    50521 ttatcgttta attatgcaaa aatatctaat catgtaagag catttatttt aaagtagcta
    50581 ctcttatatt ttatttttta tcaattacat gtattagaat aatttttaat tttaaactct
    50641 aatttatgat gatttttata atatgttata tattttaata tatggagata gatattaatt
    50701 tagtgatata tatttaagta ataagagtaa agcaaaaatt agtgcatagt agtatataaa
    50761 aatggagttt gaatactttt gttagtatat gattgtttag tagaaaatca ctataaaata
    50821 ggatttctat ctttgagcat aattatagag agcctaagta gggggaaggg tttcaagaag
    50881 atattattag tgtttgtgtt agtaaattat gtaaacacat aaaatatatt gaaaaataat
    50941 attatatata atattattta tgtgtgggaa atacgaatat aaaaaataaa aaataatatt
    51001 cggaggacat aaatatgtta agcaacaaaa agagaagtat ggcaatagta atggcaggtg
    51061 ctacagttat gagtgcagca gcaccaatat tcgcagacaa taccgtgaca gaaaatgttg
    51121 ataaaaatta cacagtaagt gcgaaagatt ctgctaaact aatcgaagag gttagaaaag
    51181 cattagaagt taagtttgaa gatacaaaag caggagcaaa tgtaaatgat agagtttacg
    51241 atataaaagt agacaatgta aacttaacta atgcaactca attacaaaat aaaataaact
    51301 ctttaacaga agggcaaagt ttaaaagtta ctattcaaga taaagggcat caagtgttag
    51361 gtggaaaagt agttgactat aaaattgaaa actacaaaac tgctcaagaa atagtagatg
    51421 cagttaatgc ttacaatgca actttagcag aagattctga taacaagtta acagcaacta
    51481 taaaatctac aaatacagtt gaagtaaaaa gagcaaaaga ttcagcaaat gttattacat
    51541 taaatgtagg agaccaacat ttagatttct caaaagtgat aacatcagaa gaaggtactt
    51601 ttgaaggtta tgaaaagagt tatagtgaca tagattcaaa agaattacat acgataacag
    51661 ttaaaaacgc agatttacaa gacatatcag cagaagaatt atttgatgga attagattaa
    51721 ctacattagg aagagaaata gttaataaag ttaaaaatgg atatgcttta acatttgaaa
    51781 atgaagcaat ccttactcaa gaacaagaag atagtgatga taaagataaa ccagaaaaat
    51841 caagctttga tatagtttta agcaaggcaa atgaaaagcc agaaacaata agtgtttcaa
    51901 gtaaaaacca taagttagtt agagacttac acaaagtatt aactgatgta aaagatggaa
    51961 aagaattaaa agtagaagtt ttatctggtg attcaagatt tacaacagca gtagaagtta
    52021 gtaaagagag atttaaagat ggagaagcag aagctataat tttagttgga gaagatgcta
    52081 tagttgatgg attagcatca gcaccacttg cctctcaaaa aaatgcacca atattattat
    52141 ctaaaaaaga ttcactacca tcagaaatag aagctgaaat attaagagta cttggaagta
    52201 atctatcttc taagaaaata tatatagtag gtggagaatc taaagtatca aaagaaactg
    52261 aagaaaaact ttctaaatta ggtgtaagta aagttgagag agtttctgga gaagatagat
    52321 ttgaaacttc tttagaaata gcaaaacaat taaaagatac atttaagact gcttttgtag
    52381 taggtggaaa tggagaagct gatgctatga gtatatcagc tagagctgct caatttggtg
    52441 ctccaataat agttacaggt aacgaattag atgcaaatgc tgaaaaatta ttaaaaggaa
    52501 aagaattaga aatagtgggt ggagaaaatt ctgtatcaaa agaagttgaa gacaaattag
    52561 ttgatataga tttaaataat aaagttgaaa gattagctgg agaaaataga aaagatacta
    52621 atgctaaagt aatcaataaa tactatgcag gtgcaactaa agcatatgta gcaaaagatg
    52681 gttatgtagg tggaaatgga caattagttg atgcacttac agcagcacca cttgcagcta
    52741 gttcaaaggc tccaatagta ttaactacag aagaactttc taaatcacaa gaagaagtag
    52801 ttgagttaag acttaagaat gctactaagt tagtacaaat aggtgaagga atagctaaaa
    52861 acgctattga aaaaatagca gaaaaaataa acttatttac taagaactaa taagatatag
    52921 gaattaatat taaaagttta tttagataat atatgattat acaatgcgtt aatatgtaag
    52981 acatagtgta gatattataa aatatacaaa taacaagata aaataataaa aataaggtgt
    53041 ctcatttaga attagattga gataccttat tttatttttt gattataatg ttgagaaatt
    53101 catattgcaa aaattattat aaaaagatac ttcttataat gattaaacat attactaaca
    53161 taaattattt tgaacttata acgtaattaa ataaaataaa ttataatgtt ttgaatttat
    53221 agagaataaa aactttaggt atattgtttg agttgtatgg ataactatgg tatcatatat
    53281 aaaatatggt aacaaaattg taacttttga ttaaaaataa gtatgagtac taataaaaaa
    53341 tatgaaaagt acattggggg tagaaaataa tatgaagaat agtaaaaaga tattagctat
    53401 aggacttaca ctatttttag taatggtaaa tactcctatg gtaaatgcgt tgacatcagt
    53461 tgagcaaata aaagggaatg acagatatga gacagcagca aaaatagcag ataagcaaaa
    53521 ctacaataca gcaatactaa tcaactcaga taatagctta gcagatggtc taagtgcaag
    53581 tggtttagct ggagccttaa atgcgcctat tttgatgaca aaacaaaacc agattccaaa
    53641 cacaactatg gaaagattaa acaaagcaaa gactgtgtat ataataggtt cagaatcaac
    53701 aataagtaaa aatgttgaga atcagttact atccaaaaag aaggttgtac aaagaatatt
    53761 tggtgaaaat agatttgata caagtataaa aatagctgaa aaaatcaaag aaattaagcc
    53821 aatagataaa gtaattatag ccaatggatt tacaggagaa gcagatgcga taagtgcatc
    53881 accagtagct gctagagatg gagtacctat aatacttaca gatggaaata gtgtgggatt
    53941 tgacacgaca ggcttaaaga gttatgcgct tggttctagt gaaataataa gcgacgaatt
    54001 agttaagagc acaaattcta ttagattggg tggcacagat agatttgaaa ctaataagat
    54061 agttatacaa gagttttata aaaatagtaa agaattttat ctaagtaaag gcttacaatt
    54121 aacagacgct ttggctgcct ctacaatagc aaaaaatgct cctgtagttt tagttgaaaa
    54181 tggcagtaac aagagtattt taagtggtgc agacaaattg actgtactag gaggcataaa
    54241 tcagaatgtt atcaagcaat gtataaatca agcttcacca aatcaacaag gtttatatta
    54301 caatccaaat gatagagcat ttaaagagag aataaagggt aaagtatatg ctcttacaaa
    54361 gcagtataga aaagagaatg gagtaagagc gttatctgta gcaagcagat tagagggtct
    54421 agcaaatgat tggtctaatt taatggcaaa taagaagact ttatctcata cgataaatgg
    54481 aaaaaattca tattctactt ttttgaaata cttagattgg agtgagatta aacctggata
    54541 tatagcagtt caaggtgaaa atataattaa atataaaatt ccagataaac ctgtatatac
    54601 aaatagagat gcagatgata taggaaactt tatttttaat gagtggaaga caaatccaga
    54661 agaaggaact aatatgttgc ataaagggta tgaaataatg ggatttggta tagctataac
    54721 aggagataag aatctatatg ctacacatga attttatgga agatataaag aataagaaaa
    54781 tatacacaaa attatgcttg taaggaagct atataaataa ttaaattata atggaaaata
    54841 gcatttatat taataaatta atataaatgt tattttttta taatttaatc taaaaaaatt
    54901 atattaaaaa gtttaaatat agtataaaat gggtaagaaa gtagtgaaaa ttaaatggca
    54961 aaattaggga aatctaatga cgcaaaacta tagggattaa agcttttaaa gccatatcag
    55021 ccagttgcta aaaagagtaa agtcttttta ttttataatt aagattctct ttgagtgtct
    55081 ttttttattg tctgaaactt atagtattta aattcatgaa aaattagata tttattaagg
    55141 gaggattgtt atttcatgaa aaaggcaata tcttgtgtac tagcagtatc tatgtgtagt
    55201 gcaccactaa acgtttttgc agaacctata ttagagggga agctaagggc agttgaaaaa
    55261 tcagttacag aaaagttaag ggggagtctt gaagtagatt taaatttttc actgccaata
    55321 aaaaatagcg agtcagaaag tatgactaat atgcagttac gattaaaaga tgatagtaac
    55381 aatagtggaa taataaagct tggagaaaaa gattcaggaa cagtaaatgt tgggacagat
    55441 aatatagaat atactataaa aaaattatct gcaagtagaa gtgaaataaa aaataaagat
    55501 gagaatatat catattataa tattgtattt aataatttac ctgttggaaa atacaatgta
    55561 gaagtctctg gagatggatt taagaacaaa gaaattaaag acattgatat atcaagttat
    55621 tcacaaagag tcttattaag caatagagca agtgtagata ataaaaataa acctttaaat
    55681 tatgaattgt tcttaatggg tgatgtaaat ggagacggta aagtagataa gagtgattat
    55741 aataaggttt tagagaatat agattcaaat aaaagagaat ttgatttaaa tagagatgga
    55801 aaggtagata ttgttgactt agattatgta cagaaaaatt taggacaaag tgaagatgca
    55861 aaaagcctag aaagtatagt atctaccaat cctatagtag atacaagtaa ggttgaatta
    55921 aaaggaaata gtgatgtaga tattaatggt aatgtagaaa atttatttag tggagaaaat
    55981 aatggagtta caatatcttc aaaaaatgat gaaatatctg aggaaaaacc agcagtaatg
    56041 gatatagctt tatcagaagc acttaatatg gaagtcatca atataaaagc tccagaaggt
    56101 actgctccag caaaaggaat agttgaggtt actgacaaag atggtaatgt tcaacagatt
    56161 ccttatgaaa acaaagaata tatgaaaaac ttaaaagatg aggagcaaca agaggaagta
    56221 aataacgaac aagaagaagt aaatcaagaa gaagtaaata ataaagatga aaatataaac
    56281 cagactgata ataactcaaa taataaagat gaaaataatg ataaacaaca ggaaaatagc
    56341 gataaacaag aagcaaactc taataccaat caagataaaa ataatgataa agaaaattca
    56401 tcaatggata aacctaattc agatgaagat actccaaaag aagagggtaa tatcagtaaa
    56461 gatgataact ctacaacatc tacatatagt aggtcagcat tagaaacata tgcagatgtt
    56521 caaaatagtg atatagtaat aaatcttggt aaacaagtag cagtaaaaaa gataactata
    56581 aaaataacag ctacaacagc aaacgataga aatcttgcag aaatatcaaa agttgaattt
    56641 ttaaacaatg tatataaaga aataccaaag ccagagatga acatacctaa aataaataaa
    56701 atatcgacta gcactgctgt tggaaatgaa aaagtatctt tttattggaa taatgaagta
    56761 aatgtatcag catacgaact tatactagac aaaattgata gtaagggaaa agtattatct
    56821 actaaaaaat tacaaactag taaaaataca atagaagtta gagatataga agcatatgga
    56881 ctatatagag ttagcataca atctttaaat ggagattggt ctagtggtta taaagatgca
    56941 acaccagaaa acttagacgg agtaccagaa aatgtagatt caaactataa acctatacaa
    57001 tttagcccag atagtatatt agaatttcaa gttgttccag acacaaaacc agaaccacca
    57061 gaaggtataa atgttaaagg taaatttaaa tctcttgatg taagctggaa aaatcataaa
    57121 caagctaaag attttgactt gtactataaa gaaaaaggct ctaatgggtc ttggataaaa
    57181 tacaatgata agcttattcg tgggacaagt tcaaagatag aaggtcttaa ggataataca
    57241 acatatgaag tcagaatgac agctactaac cacttgggaa ctagtggaat gtctaaaaca
    57301 tatataggta caactgaaag catggatgca ccaacaacac ctaactatag attaattaat
    57361 actcctaaag aaaatggtgg atttggaata ccaacaaatc acattgtaga tgttgtttat
    57421 ccagatggat atgacaaaag tgaatatagt gataaaaatc catttgataa attcaatgta
    57481 gtagatgggg actttacaac acattggaca ttcccaacat ataatgcagc tgagggaacg
    57541 aatagaggac caataataac ttttgataaa tcttatacta tggatacttt tatggctaca
    57601 cctcgttttg atgtttctga taagacaata aatgactttg aggtacgata ttgggatgaa
    57661 aatggtcaat tacacaatct gggggatgtt ccttttgaaa caaagacaga ccctgtaaat
    57721 aataataagt atgtaatggt tagattaaaa gaaccaataa ctgctaccaa gatacaagta
    57781 agtgtttgtt catcctattc atataagtct aatatatcag aacttaagtt ttatgagtat
    57841 gacagtatag aagatgatgt aagaaatcta tttatggatg gcctacaagt tgaattaaaa
    57901 gaagatgtaa ctcaagaaaa aataactgaa ttaaaagata gattaaatac tccagataaa
    57961 gctagtggag aatatcatcc atataagaca gttattgaga gagaattaaa attagctcaa
    58021 gacttatata atgatagagc cacacttact gatgtaacta ctgtaaatca agaaataaat
    58081 aaattaggaa aatataaaga taaaaacgga cagtatactg taaattccaa taatttaggt
    58141 atgcaaaatg actggcaggc attaggagta gctgctagag caggagatga aatcacagta
    58201 tatgttggaa gtaaaagtgg aaaaactcct aagttgatat atacacagta ctatggagaa
    58261 tctggtgcat ataagagtgg agaaataaat cttaacactg gaaaaaatgt aattcaatta
    58321 agcaaacttc atagtttaga tatagaatgt ggaggaagtt tatacataag atacgctgaa
    58381 gatactccaa gtggaggaga tataaaagta cgtgtagcag gagctactaa gataccacat
    58441 cttaatctaa atggaacaat aaatgataag agtcctgcgg gagtttctga atctaagaaa
    58501 aagataaaag catatataga agaattagct aaatataaag atgctgtaaa aggagaacca
    58561 tattatccag gaacaaatgt tggtaattca tatggatatt cagaaaaaac tggtgtgtta
    58621 aacactacag atattgaaag tgataaagta acattaaatg ttcctgcaac agcagtatat
    58681 caagagatat caaaaggaaa ttctgattta aatacacaag tagatagatt atataatagt
    58741 atgcttgcat gggaacaaat aatggattta gtttactcag aaagaggagt atttaaaaca
    58801 caagatttag atggtaatgg aactgtagat gataatgaat ttaacttaac taaaaatgat
    58861 atggctccaa aatctcgtat gaacataaaa taccaaagaa tgtttattgg agcatttatg
    58921 tatgcttctg gattacatgt aggagtagaa tatggttcag ttccagggct tatgaatgga
    58981 gtacctttcc aaatagatga tagtggaaaa gctacaggag gaaacttatt tggatgggga
    59041 ataggtcatg agataggaca tgttacagat attggaaaga tgacatatag cgaaactagt
    59101 aacaatgtac ttgctttact tgctcagacc tttgatgata agacacattc aagacttgaa
    59161 ggttcaacaa tggataagat atatgagcat gtaacttcaa atagcttagg tataccaagc
    59221 aatgtatttg aaaggcttgg aatgttatgg caattacatc tagcttatga tgatgatttt
    59281 acgggttcaa tgttaaagaa taactcagat gctgatttaa gtaatgatac attctatgca
    59341 aagatttcaa gaaaatacag agcactttca agtagtgacc caattaatag tttaccaaaa
    59401 gaccaaatgc tagtagcaat ggcatcaagt gttgttgaaa aagatttaag agattacttt
    59461 aaggcatggg gagtagaaat tacaccagaa ttaaacagta taatggatag caagaactac
    59521 gaaaaagaat caagaaagat acaatatgta aatgatgaag ctagaagaaa gattttaaat
    59581 gaaaatatag ctagtatggc aaaagatact aaagtaagtg ctagtttttc tgatggaata
    59641 caaagtggtt ctctagttaa atctaataaa atatctatag acctagatgt agataaggat
    59701 aaagataaga tactaggata cgaaataata agaagtgatg gaaattattt agatggtgaa
    59761 aatggaacac aggtaaaata cagaacagtt ggatttgtgg atgcaaaagg aaatagcaag
    59821 actaaattta ctgataatat atctcctctt aataacagag catttacata taaggtagtt
    59881 gcatatgatt atcacctaaa tccaacagaa gaatttgaag ttggtactgt aaaattatca
    59941 gatgaaggga aaataaataa atcagcatgg tcattcataa caaatactgt ttctgacggt
    60001 gatgttagaa ctgaaaatga ctcacatgga ccattacaaa atcctgaaat tgataatata
    60061 aaagataatg atgcaagtac tacatataaa ggaaagataa taagtaaagc agagtggaac
    60121 aaagaccctc aaaaagaccc tgatataaat gtagaagaaa atccatatat aatagtagac
    60181 atgaaagaaa cattacctat agtaggacta aaatatacaa aaccagagac agaagctaga
    60241 aagttctcat taaaaggatt atttaacttt agaaagaata ctagcacaac atacaatcct
    60301 ttaactaatt acaagataca agtaagtaat gataaaaaga actgggaaga tgtaagtcaa
    60361 ggaacttttg aatatggaca agatttagtt ggtggaggaa aagaccaaga taatgaagct
    60421 agagttacat ttaataaaga tggtaaactt tggacatacc aagctagata tgtaaaacta
    60481 atctcaaata ataagtctaa tatagaagtt gcagaattag atataatagg acctccaggt
    60541 gataatatag aaattggcat aataaataat gcagacgaaa ctcgtactaa tggaattgga
    60601 aaattagcag aagattatgt atatcaaagt gatgactcta gcacaagtga agatgaaaca
    60661 ggtaagattc cagcgggttc aatagttatt acaggtgaat acagtggaaa tccagcattt
    60721 aatttaccac tacttataga taaaaacaat aagactatat ctggagaagc acttttattt
    60781 gcagaagttc cagaaaaagg tgaactaggt gaaatcagta aaggtacatg ggtttactat
    60841 atgccaaaag aaaactttga ttctttaagt gataaggtta aggctgaact atatagatac
    60901 aatgaccttc aaggagatac tccagtaggt caaagatttg taagtgatac aatgtatgta
    60961 cctgtaggag ctaagaatta tgatgagtta aagacaataa gtcttactga tagtaatagt
    61021 aaagctagaa aagctacaag aaattctatt gatatcagta ataagaaggt tataactgta
    61081 agcaataaag taaagggtaa tattgttaga gataaatagt aggtggaact ctaaaaacgt
    61141 aaaaatacta acattgtata tctaataaga ttaggtacta gaatagtttt aaaatagtag
    61201 atattaaaag taaagtatat aaatgtaacc ataaatttag ggtaatttat aaattaaata
    61261 taaaagctag gtggataagt aaatttatcc acttagttaa tgatagataa ggacgggtgt
    61321 taatgagtaa aagaaaatct tttataagaa ctatagcagt atcaactatg gcagtagctg
    61381 taactggtag tgctacatgt gcatatgcag ctccagtttt acaaggaaca aaaacgtatg
    61441 agaaagtaaa tactatagat atatctgtgg actcagtaga aaacatagta tattcatttc
    61501 aagccagtat aaaagtacaa ggtgaggttg aagtagtaga taatgagcag aaagaaaaga
    61561 ttacttggtc tgataatata aaatctcaga taaaaagtgg aaatgcaaat gctacttgta
    61621 gagtagaata caacaaatca agtaatacaa ctacattaga tatatatgtt acatcaaatg
    61681 aagatttact agacggaaat agattgaata taggaagaat atctgtaaaa aaatctggca
    61741 gtaactcaaa tgctgactat aaagttttag gaaaaggaac aaatgataaa ccagctttaa
    61801 aaattgtaac atataacaac aaaacagtgg attatgaaaa tataagctct gatgaaggat
    61861 taatatttac ccttattaat gagagtgaag taaaaccaat tggtggaact ggttctagta
    61921 aaaatgaccc tgaaaagtat aaggtagaga aaagtgaagc acttgaatat ttattaaaca
    61981 atattaggat aaactattct attgttagta aagaaacaca agaaagtggt tcaaatgtaa
    62041 tattaaaact tggattagca caaaaaacaa ctaagggaag aaaagctaca ataaacaaat
    62101 atgttgaagt tacacttcca aaaagtttag aatacatagt tgaaaatgaa ttatcaaaac
    62161 cggatgaatt accaccagat aatggcaatg gtggaaataa tggtggagga agtaattcag
    62221 gcggctcatc tagtggtgga agctctggag gaggaagttc aagtgattct acatctaatg
    62281 tcacagtcaa aaaattaaaa ggtgctgata gatttgagac agctatcaaa atatctcaaa
    62341 gtggttggac aaaatcagat acagttgtaa tagtaaatgg agaagataaa agtatggtgg
    62401 atgggcttac agctacacca cttgctagtg taaaaaactc accaattctt ttatcatcaa
    62461 atgaaaagct tcctcaaaaa actgtagaag aattgaaaag gctaaatcca tcaaaagtaa
    62521 ttgtgatagg tggaaacaac tcaatgccaa attcagttgt tgaagctatc aaagctgtaa
    62581 attcaaaaat atcagtacaa agaataggtg gagatacaag atatcaaact tctattaata
    62641 tagcaaaaga aatagataag acgaataatg taagcaagtt gtatatagga gcaggaaatg
    62701 gagaagctga ttcattatca atagcatcac tggctggtaa agaaaaaact ccaatagtac
    62761 ttacacaaaa agatggtgta gataatgaag ctgaacaatt tattaaatca aataaggtgt
    62821 caaatatata ttttattggt ggagtagaaa aaatatctaa caaggctatt gaacaagttg
    62881 gaaaaatagc aaacaaagat atatcaaaca atagggtggc aggtcaaact agacaagaga
    62941 cgaatgccaa agtaatagat aaattctact ctcaatctaa gctagatgga gttgtagttg
    63001 caaatcaaga taaacttata gatgctttag cagttggacc attagcagct aaaaacaatt
    63061 caccagttat acttgctaca aatacgttag ataaatcaca agaatcgtca ttaaaaggta
    63121 aaaattcatc aaagttgttt gaagtaggtg gaggaatagc ctcatctgta atagacaaga
    63181 ttaagagttt aattgaaaaa taaatattaa gtaaatagaa aataagaatg tatttagata
    63241 taaagttata tatttaaatg cattcttatt ttattttcat tatcttaaca atctaataat
    63301 attgaggtta aaatgtataa taatttgagc tatattaagt ttaattttaa ataaagcaga
    63361 tatcttttat atatataaat ataaattcaa ttttgaatat gtttaaaaag aagttaaaaa
    63421 taatttttta aatttaataa aataaaacac taatatatag acgagatata ttcatatcat
    63481 atatactcta taatatatgg aaaataaaga gaaaataaat ggaaaataat cacaatataa
    63541 atataaaata taaaaatcat cagggggata tgaaaatgaa caaaaaaata ttatcattag
    63601 gtctagcagt atcattaatc ttagtaaact tcaaaagtgt aaatgcatca tcagtagtag
    63661 aaaaaatata cggtaaagat agatatgaaa cagcagcaaa gatagctgat aaacagactt
    63721 atgaaacagt aattttagta aatacagaaa aatcacttgc agatggatta agtgcaagtg
    63781 gattatcggg agctacaaaa gctccaatac tatttacaca acaaaataag ataccagcag
    63841 acacaaatag atgtctaaaa aatatcaaaa aagcatatat aataggtaca gaagatacta
    63901 taagtaaatc agtagaaaaa gaactagatt ctaaaaatat agaagtcaaa agaattggtg
    63961 gagaagatag actaaaaaca agctatttaa tagctaaaga aatagcaact ataaaaaaag
    64021 tggataaagt actattaact aatgcatata gtggagaagc agatgcaatg agtgtatcat
    64081 cagtagctac tagagatgga gctccaatca tacttacaga tggaaagagt gtgccttttg
    64141 atgtaaaaaa tattcaatca tattgtatag gttcagagga gataatgagt aatcctctag
    64201 ttaaaaatac aaactcagta agaatagaag gaactgaccg atttgaaact aacaaaaacg
    64261 taatagacta cttttttaat agtgcagatg gattctatgt atcagatgga taccaattag
    64321 tagatgcaat agcagctgca ccacttacta aaaactctcc aatggtacta gtaaatgatg
    64381 gaagcgataa aactgtatta gaaggagcta agaatataac ctctgtaggt gaaataaatg
    64441 agaaggtaat acaacagtgt ataaatgctt caaattcaaa tgggcaaccc ccaacaatta
    64501 cagttggaag tacagaggta tataagggtg aaaagtttga cactggcaag ttaaatatag
    64561 tagctaaaga taacacaggg aaggtattac caatagaagt tgatgggttt atagatacaa
    64621 atagagtagg tacatacata ttgacattaa aagctacaga cgaatgggga aaaagcacag
    64681 gaaaaagagt agaaataaaa gtgttggatg acaaatctca tgattacaac agcccagaat
    64741 ttaaaaaaat ggtatctact gaaatgtata acttaatcaa ttcctataga aaagaaaaag
    64801 gcaaagagcc tttgctagtg tctagtaggc tagaaggtat ggcaaatgca tggtctaagt
    64861 atatgatgga taaaaaagta tttgcacatt atatagatgg aaaaaatgct ccacaagtat
    64921 tttctgaatt tggaatgaga agtgaggaaa atatagcata tatttatata gattctaaga
    64981 acgttcaaac gacacaagat gcaaaagact tggcaaaggc tatatttgag gtgtggaaga
    65041 agtctccaga gtacaatgca aacatgctta gtaatgagtt ttatagtact ggatttgggc
    65101 tttatatatt atctgatggt caagtgcatg ctactcagga gtttttaaat ggaaatgaag
    65161 gtagcttgta aaaaattcca taaatcttgt ttttttgtta atttactgat attataaaat
    65221 gaaaatcaca tctaaagtac tttttgtaat ctgttttgtt attgctttac aggctatggt
    65281 attttaggtg ttttttgttt tagtagttta tagattttga gggaatcact actgaggatg
    65341 taatttatga ttagctgaat tatataaaaa aattagtagg aggagtttga tgaaggtaaa
    65401 taagagagta ttatcaatag gattgacaat atcattaata atggcaggag caccaaatat
    65461 caatgcactt tcgagcatag aaaagataca ggggaaagat agatatgaga cttctgcatt
    65521 gatagcagat aaacaaatat atgatacaat catattagta aatactgata attctatagt
    65581 agatggatta agtgcaagtg gattatctgg agttgcaaaa gctcctataa tgttggtgca
    65641 aagagataag ataccaacag atgttgaaaa aagactaaag gatgttaaga atgcttatgt
    65701 tataggtaca gaggatacaa taggtaaatc tgtagaaaat caacttaaga ataaagggat
    65761 tgaagttaaa agaattggtg gggaagatag aataaagact agctatctta tagctaagga
    65821 gatttcagct attaaaccag taaatgatgg tgataaggtt tttcttgtaa atggatacac
    65881 aggtgaggct gatgcaatga gtgtatcttc tgtagctgct agagatggag ttcctgtgat
    65941 acttactgat ggaaagagta taccatttaa agttgatggc gttcagtgct attctcttgg
    66001 gtcagaggag ataatgagta atgaacttgt gagtaagact aattcagtta ggattgctgg
    66061 taaggatagg tttgaaacta ataagaaggt tatacaacgc ttttataaag gaacaaagaa
    66121 gttttatgtt tctcaagggt ataagttagt tgatgctgtg gctggttctc cgttggctaa
    66181 ggacaaacct atagtacttg ttaatgatgg aagtgataag agtgtgctta gaggtgctga
    66241 tgaagttact tctttaggtg gaatggataa gaaggttgtt gaccaatgta ttagttctgc
    66301 atctgataaa aatacaatgc ctacaattac tgctaatgat gtagagattt ctgtagggga
    66361 taagtttgat aatagtatgt tgaatatagt tgctactgat tattatggaa atgatttaaa
    66421 ggcaaatatt aaaggaaatg ttgatattaa caaggctgga acatatgttt taaatataag
    66481 tgtagtggat aatttaggtc agaagagtga gattagtgta aatgttaagg tagttgtaaa
    66541 tgcgagtaca aaagactcta atagttatga gtttaaggct atggtatcta atgagatgta
    66601 tgatttagtt aattcatata gaaaagaaaa aggcaagaag agtttaagag agttagactc
    66661 tttagctgga atggcaaatg catggtctaa atatatggaa gataagaagg tatttgccca
    66721 tgagattgat ggtaaaaatg cagctgaagt attttttggc tttggagcaa gaagtggtga
    66781 aaatattgca tatctaccaa tgaatgttaa atctgtttat acttctaaag atgcaaaaga
    66841 aatggctgag tctatttttg atttatggaa gaagtcttct aagtataatg aaaatatgtt
    66901 aaaagaagaa ttttatagct ttggatttgg tatgcatgtt tctagtaaag gagaagtgaa
    66961 tgcgacaatg gaatttttaa atagttagat tttatattaa tttacattgg aaaagatata
    67021 gtaaatttgt aaaaataaat atataaaatt aaaataactt ataaaattat aaaaaataat
    67081 ttaaaaataa taaaaatgat gaaaaaacaa ttaatttgtt ggaaaaaact tcaattaatt
    67141 ttgcataaat tattgaattt atattttata tagtctatca taagagtgtg agaaatattt
    67201 ggattatatg aacatggaaa tttaatgtac ataattaaag agatgtaatt aatataatgt
    67261 tgggaggaat ttaagaaatg aataagaaaa atttagcaat ggcaatggca gctgttactg
    67321 ttgtaggttc tgctgctccg atatttgctg atactactgt taaagaagaa ggatatacgg
    67381 tagtacaaga caaatatgaa aaattactta aagaattaaa ggcaaagata aaagatggaa
    67441 ctattacatc agttggtgtt gaatttgatg gaaaaccaat tactacatta gcaccaaagg
    67501 cagatggtag tgataaagat gcaatagcag aacagttaga aactcttact aaaaaccaac
    67561 ttaaaggttt aggtgatgga aaatatgtag attttaaaat tacttatggt gctaaagcag
    67621 aagttccagc tgcttcatta agtgcagatg atatacaaaa atatgcagat caaataaatg
    67681 cttctgagaa aatattagtt gaagtagcag caggatctga agcaggtata gcaaaatttg
    67741 attctgttaa caataaagtt atagcaggag atgctcctct taaagttaaa gatgcagtga
    67801 aagcgactgt tactactaat ggtagtaata aaaaagttct tacaatatca gctgcagctg
    67861 gattatcagg attttcatat ggaacactta aagacacagg tgcaagttca tctgatgttg
    67921 atgcaataac tcttgacact acaaatgcaa caataacaga aggtgatact aaagtattag
    67981 attttgataa ttcatttaag tttaacgaaa gtactaaaaa agttggtagt ttagttacac
    68041 caaatacaac aaacactcca gcagatcctg gtactaaaac tactgttaga gtgataaaag
    68101 ctgttgaaaa aacaatagat gtaagttcaa attcaactac aaaagctaaa gatttagcta
    68161 aacaatatgt attcacagat gttagtgata ctgatccaga aagtttaagt tatatgctta
    68221 aaaacataaa tgatggaaaa gttgctgtta aaaattctga tggagattat gaagtaacta
    68281 tattcccaga aggaaaaaga ttaaatactt tatctgcttc ttcagctaaa actattttag
    68341 gagataaaga tactccagca aaaatagttt taaaggcttc aacaacaaag aaattagcag
    68401 actatataga tgatttaata acttataaca atagttattc aaatgtacaa actgtagcag
    68461 gtagtgatag aatagagact gctatagagc taagccgtaa gtactataac tctactgaca
    68521 aaaatgcttt atatggagat cctgtaaata acgttgtatt agtaggttct caagctatag
    68581 ttgatggatt agtagcatct cctttagcag cagaaaaaga tgctccttta ttgttaagtt
    68641 ctaaagataa attagattca tcaacaagag ctgagataaa aagagttatg gacttaaatt
    68701 cttcaacagg aataaaaaat aataaagaag ttttcatagc aggtggagta aattctatat
    68761 ctaaagacgt tgaaaatgaa ctaaaagata tgggacttaa agtaactaga ttatcaggtg
    68821 atgatagata tgaaacttca ttagcgatag ctgatgaaat agatataaat gataaagctt
    68881 atgtggtagg tggaacagga ttagcagatg ctatgagtat tgctccagtt gcatctcaaa
    68941 taaaagatgg tgaagctact ccaatagtag ttgtagatgg aaaatctgac aagttatcta
    69001 aagaagctga agatttctta gatgatgcac aagtagatat aatcggtgga gaaaatagtg
    69061 tttctgctaa aatggaagat tatatagatg atgctactgg aaaatctcca gaaagaatta
    69121 gtggtgctga tagacaagca actaatgctg aagttataaa agaatacttt gataaagatg
    69181 gagtttcaaa ttacttctta gcaaaagatg gttcaactaa agaggatcag ttagttgatg
    69241 cattagcagc agcagcagta gctggaaact acggttctaa gcataatgaa gatggagata
    69301 taactacaga tgcttctcct gctccaatta ttttagcaac tgataattta tcagctgaac
    69361 aacatgtagc tgtaagtaaa actgctacta ctaatggtgc taagaactta gtacaagtag
    69421 gtcaaggaat agctgattca gttgttagca aattaaaaga tttattagat atgtaatata
    69481 aattttatat attgaataaa aaaggtttct cttttgagaa acctttttta ttttaaacat
    69541 aaatttttat aaataaaaag aggctaatta gcctcttttt aatgtgagaa acacttaaaa
    69601 aataagatgt aattatttat ttaagtatca ttattatact ataccttaaa ataaatgtct
    69661 actattctat aattttaagg tataatagta agtggaaaat aaataaggag gtaaattaaa
    69721 tatgtcagtt ttagatgtaa tattagacaa aacagatgaa ttagaaatta aaaaattaaa
    69781 taatatagta gataaaatag atgctttaga agataaaata caaatactag atgatgaagc
    69841 attaaaaaat atgacgaatg tatttaagga taagttaagt aaaggagaaa ccttagatga
    69901 catattgcca gaagcatttg ctgttgtaag agaagtatca aaaagaatat taggtatgcg
    69961 tcaatataga gttcaattaa ttggtgggat tgtattacat caagggaaaa tagcagagat
    70021 gagaactgga gaaggaaaga ctctagtagg agtagctcca gtttacttga atgcattgac
    70081 tggtaagggg gtacatgtca tcacggttaa tgattacttg gctcaacgtg ataaagaact
    70141 tatgcaacca gtatatgaat ttttaggttt aacagtagga gtaattatta atgggcaaca
    70201 gccagtagaa cgaaaattac aatatcaatg tgatattact tatggtacaa acaatgagta
    70261 tggattcgat tatttaagag ataatatggt aacgcaaaaa tcagagaaag ttcaaagaga
    70321 actaaacttt gctatagttg atgaggttga ttcaatactt atagatgaag ctagaacacc
    70381 acttataatt gctggtggag gagatgaagg tactaagctg tatgaacttg caaatgcttt
    70441 tataaagaat ataagagatg aagattttga aatggataga aaagataaaa ccatagcact
    70501 tactgcaagt ggtcttagta aagctgagaa attttttgga atagaaaata taactcatat
    70561 agataatata gaaatttttc accatgtaaa tcaatctcta agagcacata aattaatgaa
    70621 catagatgtt gaatatgttg ttagagataa tgagatacta attgtagatg aatttacagg
    70681 aagaataatg gatggaagaa ggtttactga tgggcttcat caagcaattg aagctaaaga
    70741 gggagtaaaa ataaatgatg aatcaaagac catggcaaca gtaacatttc aaaatttctt
    70801 tagattatac tctaaattat caggaatgac aggtacagca aagacagagg aaagtgagtt
    70861 tgaagctaca tataagatta atgttgttca gataccaact aataaaccag ttataagagc
    70921 tgatttacat gataaagtat tcaaaacaga acgtgcaaag tacaatgctg ttgtagaaga
    70981 aataataagg ataaataaaa ctaagcaacc agtgcttgta ggaactgttt caattgaaaa
    71041 atctgagaaa ttatctaagc tacttaaaaa gaaaggtgta aagcacgagg tcttaaatgc
    71101 taaacaacat gataaggaag ctgaaataat atctaaagct ggtaaattag gttctgttac
    71161 aattgctact aatatggcag gtagaggaac tgatatatca cttggagctg gagataaaga
    71221 agaagaagaa aaggtgaaag agttaggtgg cttgtatgtt ataggtactg aaagacatga
    71281 gacaagaaga attgataatc agcttagagg gcgttcggga agacaaggtg accctggaac
    71341 ttctagattc tttgtaagtt tagaggatga agtaataaaa ttgtatggtg gaaaaagtat
    71401 agaaaaaata ttaaagagaa tgaatgctaa tgaagatgac gcgttagaaa gtaaggcttt
    71461 gaatagagca atagaaagag cacagaaagg cattgaaggt aaaaattttg aacaaagaaa
    71521 gaatgttctt aagtacgatg atactattaa tgagcaaaga aaagtaatat atgatgaaag
    71581 aaataaggta ttggatggtt ctgatattga agaagagata caaaaaatgg ttatggatat
    71641 tattacggag gctgctgaaa agtacttaaa aaaatttaga gactatcatg gatattttaa
    71701 gtatttatat aatactttta tgccagctga tactttatta attccagact tagataaaaa
    71761 aaatgttgaa gaaatagtaa atcaaacata tcagatttca aagcgtgttt atgatcttaa
    71821 gaagatgatg attggaattg aagaattggc tcaattagag aaacgagtat tacttcaagt
    71881 tgtggatact tattgggttg accatataga tgcaatggat caactaagac aatatatagg
    71941 tcttaaatct tatgcacaaa aagatccatt taaagagtat gctatagaag gttatgaaat
    72001 gtttgaagct ttaaatagga atataagaat aacaacagtg caatatctat ataaatttaa
    72061 ctaaaaaagt gacccattgg gtcacttttt atatattaag attaaagtga aatttatttt
    72121 acagtacaca ctcatataga taaatattta taataatgaa aaagaggctg aacgtcagcc
    72181 tcttttcctg tgtgagaaat acggaaaaaa gagatgcttg aaatttcttt cttccattta
    72241 atattatact ataaagagaa taaaaagtcc atgagttatc tttatgatta aaaaaaaaaa
    72301 ttacaatttt gttacttttt agtatacaat aataaattta aattgacttt gttaattttt
    72361 attaataaaa tatccaaata ttacaatatc tacagtttat tgaaataatg tgtaaattat
    72421 attataattg gtaaataagg aaaaatggtg aaaaccaaat tttgtagggg gaaatatatg
    72481 aatagaaaaa atctttatgt aattatggca gctgcaatgg taagtacatc agtagctcca
    72541 agttttgctg cagaagctac acaagtaaag aaacaaacaa taactaaaaa ggaagcaaca
    72601 gaattagttt ctaaagttag agaactaatg gctcagagat atacaggagg ttctcaagtt
    72661 ggacaaccaa tatatgaaat aaaagttggt gaaacttcat cacaattaaa aataataact
    72721 aatatagacg aattagagaa attagtaaat gctttaggag aaaataaaga gcttcttgtg
    72781 actatagcag ataaaggaca tacaacaaat agtgcaaatg aagtggttgc tgaagcaatt
    72841 gaaaaatatg aaaattcagc agacctttca gctgaagcta attcaataac agaaaaagct
    72901 aaaactgaag ctactgggat ttatggagtg gcaactgtag aagcttcata tgacagtaca
    72961 aaagataagt tagtaataac tttaaaagat aagactgatg tagtaacttc taaaacgcta
    73021 caaataggta ttggtgatga aaaggttgat ttaacagcaa atccagttga tatagcagga
    73081 accaatttag acccttctgc agaaggattt agagtaagta aaataaataa attaggtgta
    73141 gaaggagcta aaaatattgc tgatattcaa ttagctgaaa taactataaa aaatagtgat
    73201 ttaaatacag tttcacctca agatttatat gatggatata gattgactat tcgaggtaat
    73261 acaatagcaa atagtgtagg aaaatcaatt agtgatattt catcaaaaga ttcagagaca
    73321 ggaaagtata aatttactgt taaatatact gatacatctg gaaaagcgat agaacttact
    73381 gtagaaagta ctaatgataa agagttaaaa gatgttaaag atgccttaaa tggaaataca
    73441 aaagtcaatt taatagctgg ggaagacagg tatgcaactg ctgtagctat agcaaaagaa
    73501 acagaatata ctgacaatat agttatagtt aattcaaata aattagttga tggattagca
    73561 gcaacaccac tagctcaatc taaaaaagct cctatattgt tggcgtctga taatgaaata
    73621 ccaaaagtaa ctttagatta tataaaggaa ataattaaaa aaagtccatc agctaaaata
    73681 tatatagtag gtggagaatc agcagtatca aatacagcta gaaagcaatt agaatcagta
    73741 actaagaatg ttgaaagatt ggctggagat gatagacata caacttcagt agcagtagca
    73801 aaagctatgg gttcttttaa agaagcattt gtagtaggtg caaaagggga agctgatgct
    73861 atgagtatag ctgctaaagc tgctgaactt aaggctccta taatagtaaa tggttggaat
    73921 gatcttacag cagatgctat caagttgatg gatggaaaag agattggtat agttggtggt
    73981 tctaataatg tacctagcca aattgaaaat caacttgctg atattgataa agatagaaag
    74041 gttcaaagag ttgaaggtga aacaagacac gatactaatg ctaaagttat agaaacatat
    74101 tatggcaaat tagataaact atatatagca aaagatggat atggaaataa tggtatgtta
    74161 gtagatgcat tggcagcagg tcctctagca gcaggaaaag gaccaattct tttagctaaa
    74221 aatgatataa caaactcaca aaagaatact ttagataaaa aactaaatct tggtgcagaa
    74281 gtaactcaaa taggtaatgg ggttgaattg actgtagttc aaaaaatagg caaaatacta
    74341 ggatggtaat aatcaataat atagaaaagg attccttatt atttatagga atctttttct
    74401 atcgacataa tattcattaa agtataacat gctcttgaca gataggagga tatgatagtg
    74461 atagaagcaa cattgttttt ttccccacac caagatgatg aaacattaag tatgggtagt
    74521 gcaataattg aacatgtaga aagaagcgat acacatgtta tattatgtac tgatggcagt
    74581 aaatcaataa taagaaaagt attagatgat ggagggtcat gttcttatca tattaaagat
    74641 gtacacaagt actctttatc agaaagtgat ttttcaaaaa atagagatga agaatttaaa
    74701 aatagttgta aagcaatggg agttaaagaa aataatatac atatagaaaa taatagagct
    74761 catgatggag aattgagtaa ggaaaaagca agagatataa tgctaaaata tttagaaaaa
    74821 tatcctgatg ctaaagtgaa gaccgttaca ccatataaag ctcttggaat acatgaagac
    74881 catagagcat taggtgaagc tgcattagaa ttgtatagag aaggaaaaat aaaagattta
    74941 agattttatg tagagccata cgattataat gattttaaaa aagttaatcc aaatgttaga
    75001 gtatggaagg ttttgagtag tcaagaagag aaattattaa atgctatgga tgcatacaag
    75061 aaatggaatc ctgaaaatgg taactacgca attggatatc attctgtaaa atctcacttt
    75121 gatgaattaa aatccaataa aatccaatat gtacatgctc cataaacatt aatataaaaa
    75181 ctaggaggat atagttaatg aaaatatcta agagaataat gtcgttgttg acagcaactt
    75241 tttttatctt tgcattatct atcaatatag ctgatgcttc atcaaaagag agtctagtgg
    75301 gctctggtag atgggaaact gcaataaaaa ttagtcagaa tggatggaaa gatgctacta
    75361 atgctatact agtaaatgat aattctatag ctgatgcatt atctgcaact ccatttgcta
    75421 agttaaaaga tgcacctatt ttattaactc aaagtgataa attggatagt agaactaaag
    75481 cagaattaaa aagactaggt gtaaaaaatg tatatttaat tggaggtatg aatactctaa
    75541 gcaccaatat tgaaaaacaa ttaaaatcag aaaatatgac ttttgagagg atttcaggta
    75601 atagtagata tgaaacatct ttaaaattag ctgaaagatt agataaagag aagagtattt
    75661 ctgatatagt tgtagttaat ggagagaaag ggctagcaga tgcagtaagt gtgggttctg
    75721 ctgcagcaca agaaaatatg ccaattatac tttcagatcc taacaatgga ataaaagttg
    75781 caaatagctt tattagtagt aaaaatataa agaaatctta tataattggt ggtacatatt
    75841 ctgtatctag ttctattgaa cagagtttac ctaatgtaaa aagattatct ggaaacaata
    75901 gaaatgaaac taatgcaaag gttctagaag aattttataa aaatacagac ttaaaaaatg
    75961 cttatataac taaagatggt atgaaaaaac agggggattt gatagattct ctagctgtag
    76021 gtgtattggc agctaaaaat agctctccag ttgtattagt aggaaattca cttgactcta
    76081 gccaatatga tgtgttaaat actaaaagtt ttgataatat tgtgcaagtt ggtggaaatg
    76141 gaaatgaaga tgctgtaaag gatattcttg atttacaaga agaaactata tatagagtta
    76201 agacagcaga cgaattggat gttgctctaa gaaaagcaga tgctaatgat attataacat
    76261 ttaaacctga tgataataaa aaaattacta gttcatttag tatagaaaca aagaaagcta
    76321 taactgtaga gcttgaagga ttgtatacac aaacaataac tgtaaatatg ccaaatggag
    76381 aattaactaa taagggtaca ttagatggaa ctgtgaaaat aatggatata aaaaatggca
    76441 catttatcaa tgaaggtgat ataaatgata ttgacattta tgatccaaat ggatgtaaaa
    76501 tagagaataa aagtggtgga gatatatggg ttttaactat atctagtagt gctaaagatg
    76561 taaatataga aaataaaggt gatataagta aggttacaaa taattctact agcgttataa
    76621 taagaaattc aggaaatatt gatactttaa gtggaattaa tgcaccagca ataagtggaa
    76681 ataaacctag agttgatgat accgataagg atgaaaaaag agcaagtgga atatatccta
    76741 cttcagaacc tttatcacct gcaagagctg gttatataag tgtaaaaata ttcactaagc
    76801 ctgaagatac aaattataaa atttattata gagtagtaag cagtagacca tctgcattat
    76861 atatcggaga tagaatagat acaagtgact ggactgctgt accatcttct gttttaccat
    76921 ttactattaa agcagaaaat ggatattata tagaagctgt tgaaataaat tctgatacta
    76981 agaaagtatc tagatggggg aaatctgact atatagatga tggattttat ttaaaatcag
    77041 aaactgcaaa aggattaagt gcagatatag attttgatgg agattatgtt aaattaacag
    77101 caacaggtgc tgattctgga tgtacagttt attatagaat agtatcaaaa aagccagtat
    77161 caatgaatgt tggagataaa gtaactatat ctgattggga tgaaattact actaatagag
    77221 tgaggataga agcaaacgat gtaaaggata aatatataga actagttgaa ttggatgatt
    77281 caactaataa agtaactaga tggggagcaa gtgataaggt agtagaatag gtatctaatg
    77341 tgaaacataa aaacagactg attaataatg ggcagtctgt ttttatttcc taaaaattat
    77401 cattttacta aataaataat ttaaaactat aacaattata ttagtaaata cttttacagt
    77461 aatatcattt acaaaaaata aatcaatcat tatatacata ataatcattt ctataatacc
    77521 agaaagtagc ctaaaactga caaaaaacaa aaactcctta aacaaaaata ttagttcaat
    77581 tcttttactc tcaaacacaa aaaacttatt agtaacataa gcaaataaaa cagcaagtat
    77641 ccatgccaaa gcatttgcaa ccataaaatt aaataaaata actctagtaa aaaataaata
    77701 cgaaactata tttacaagag tagtaaatgc tccaaaaaat aaatataata tcgtctctct
    77761 atgctttttt aaaatcaaat ataatcctcc taagctaatt taatataaat atacttaaag
    77821 atactaacaa acattagtat aacacatcta ttaataaatc aatatatctt aaaatattat
    77881 aaaaataaaa ctataatatt ctataattaa tatgtactca taatccatat tttatcaaaa
    77941 taaaatatga ccttaattta gaaatctgat ataataaaaa ttaaatacat ataagggggt
    78001 aaacatgaga aagtacaaat caaaaaactt gtcaaagcta ctagcattgt tgacagtttg
    78061 ctttttaata gtgtcaacaa tacctgtctc agcagaaaac cataaaactc tagatggagt
    78121 agaaactgca gagtattctg aaagctatct tcaataccta gaagatgtca aaaatggaga
    78181 cacagcaaaa tataatggag taataccttt tccacatgaa atggaaggta caacacttcg
    78241 aaataagggt agaagtagtc ttccatcagc atataaatca agtgtagcat acaacccaat
    78301 gaatcttggt cttactacac cagcaaaaaa tcaaggaagt cttaatacat gctggtcttt
    78361 ttcaggtatg tcaacgttag aagcatatct taaattaaaa ggatatggaa cgtatgactt
    78421 atcagaagaa catttaagat ggtgggcaac tggtggaaaa tatggatgga acttagatga
    78481 tatgtcaggg agttcaaatg taacagctat aggatatctg acagcatggg caggtcctaa
    78541 gttagaaaag gacataccat ataatcttaa atctgaggca caaggtgcaa ctaaaccttc
    78601 aaatatggat actgcaccta ctcaatttaa tgtaacagat gttgttcgtc ttaataaaga
    78661 taaggaaact gtaaagaatg ctataatgca atatggttca gtgacatcag gttatgcaca
    78721 ttattcaaca tattttaata aagatgaaac agcatataac tgtacaaata agagagctcc
    78781 attaaatcac gctgtagcga tagtaggatg ggatgataat tattcaaaag ataattttgc
    78841 atctgatgta aaaccagaat caaatggagc atggttagta aaaagtagtt ggggagagtt
    78901 taattctatg aaaggattct tctggatttc ttatgaagat aaaactctac taacagatac
    78961 agataactat gcaatgaaat cagtatcaaa accagatagt gataaaaaaa tgtaccaact
    79021 tgaatatgct ggtcttagca agataatgtc aaataaagta acagcagcaa atgtatttga
    79081 ttttagcaga gactctgaaa aacttgattc tgttatgttt gaaacagact ctgtaggagc
    79141 aaaatatgaa gtatattatg caccagtggt aaatggagtt cctcaaaaca attcaatgac
    79201 aaaacttgca agtggaacag tatcatattc tggatacata aatgtaccta ctaattctta
    79261 cagcttacca aaaggtaaag gagcaatagt agtagttata gacaacacag caaatcctaa
    79321 tagagaaaaa tcaactttag catatgaaac taatatagat gcatattatt tatatgaggc
    79381 taaagcaaac ttaggtgaaa gctacatact tcaaaacaat aagtttgagg atataaatac
    79441 atatagtgaa ttttctcctt gtaactttgt tataaaagct ataacaaaaa catcttctgg
    79501 acaagctact tcaggagaat ctttaactgg agcagataga tatgaaacag cagttaaagt
    79561 tagtcaaaaa ggatggactt cttcacaaaa tgcagtatta gtaaatggag atgcaatagt
    79621 ggatgcttta acagctacac catttacagc agcaattgac tctccaattc ttttgacagg
    79681 aaaagataac ttagattcaa aaactaaggc agagttacaa agattaggaa ctaaaaaagt
    79741 ttatctaata ggtggagaaa attctttaag caagaatgta caaactcaac ttagtaatat
    79801 gggtatatca gtagaaagaa tttcaggtag tgatagatac aagaccagta tatctctagc
    79861 tcaaaagtta aatagtataa aatctgtttc acaagttgca gtggcaaatg gtgtaaatgg
    79921 acttgcagat gcaataagtg ttggtgcagc agctgctgat aacaatatgc caataatact
    79981 tactaatgaa aaaagtgagt tgcaaggtgc tgatgagttt ttaaattcat ctaaaataac
    80041 taagtcttat ataattggtg gaacagctac tttatcatca aatttagaaa gtaagctttc
    80101 aaatccaaca agacttgcag gcagtaatag aaatgaaact aatgctaaga taatagataa
    80161 attctaccct agctcagatt tgaaatatgc ttttgttgtt aaagatggtt caaagagtca
    80221 aggagacttg atagatggac tagcagtagg agcattgggt gctaaaactg attcaccagt
    80281 agttctagtt ggaaataagt tagatgaaag tcaaaaaaat gtacttaagt ctaagaaaat
    80341 agaaactcct attagagttg gtggaaatgg aaatgaaaat gcttttaatg aactaaatac
    80401 tcttttagga aaatagtgaa tggaaagata gtaaggatat acattttatt attaaaaaat
    80461 gttcaataga agtttataaa tataaaataa caaaaagggg tgtctcaaaa tgaacttttt
    80521 agttcatgag gcactctttt ttgttgtttt atatttttat catttaaata atgaaaaata
    80581 ggattgtcta tatttttaga tagttttctt attattgatg aaaaatgtaa taattttaaa
    80641 ctgtaaaata gtgtaaagtt attttataat ataaatatag taagatttta aacaaaataa
    80701 gggggaataa taatgaaagc accaaaaact attttaacaa tactgacaat agcgcttact
    80761 ttaagtagca tttctataat accatcatat gcacttacag aggaaaaatt aataggtaat
    80821 ggtagatatg aaactgctgt aaagataagt caaaaggcat acagttctag tcctaatgta
    80881 gtgctagtta atgacaattc attagctgat gcactttcag ctacaccatt tgcaaaggct
    80941 aaaggagcac caatactttt gacagaaagt gataagctag atgataggac tgaaaaagag
    81001 ataaaacgtc taggagctaa agatatttat ttgataggag gtactgctgt acttaataaa
    81061 gatatagaga acaagttaaa aagtaatgga cttaatgtag aaagaattaa tggtaaggat
    81121 agatatgaaa cttcactgat tttggctaat aagcttaagg atataaaaga tattaaggaa
    81181 gttgctgtag taaatggtga aaaaggattg agtgatgctg ttagcgttgg ggcaccagca
    81241 gctcaaaata agatgcctat aattttgtct agtcctaagg atggagtaga agcatttgat
    81301 aaatttataa gggatgagaa agttataaaa gcatatgtaa ttggaggtac aaattctgtt
    81361 tcaagagctg tagaaaagag tcttcctaat gcagaaagag tgagtgggaa agatagaaat
    81421 gagactaatg ctaaagttat agaaaagttt tacactgata caaatttaag taatttatat
    81481 gtaactaagg atggtagtaa aaatgagaat caactaatag actcgttagc tgttggcgta
    81541 ttggctgcaa aaaatgagtc tcctgttgtt ttggttggta ataaattaaa cacaaaacaa
    81601 agagatatac ttagtactaa aaaattaaat actataacac aggtaggtgg aaatggaaat
    81661 gaagaagctt ttgatgaaat taaaagtcta caagaaaaaa ctgtgtttga agcaaaaact
    81721 gttgaggaat taactgatat gataaatata gcaagtccta atgatattat aaactttaaa
    81781 ccaaaagaga atactgtaaa tgaagctttt agaatggtaa caaataaacc aataactgtg
    81841 aatataaagg gtgattgttc aaagactctt acagtagata tgcctaatgg tgaagtgaat
    81901 aactatgcta ctttggtaaa tgttatagtt agaaatattg gagaaggtgg atttaataat
    81961 catgatacaa tcactatatt gtcagttcgt gacaaaaatg gtagagttat agaaaatact
    82021 agaaattcag atatagatac gttgatgata ttagcttctg ctaatgatac aaaattgatt
    82081 aatgatggat atataggaaa acttatagat aattcatcta atagtgatat aactaataat
    82141 ggtactatag ataaaaaagt taatcaggtt gaagatttag aggctaaagt agattcaatt
    82201 gaaaaagcta tagattctat aagtcaaaaa gtcaataaaa tacaagatat actagataag
    82261 cttggatttc taaagaaatt tcttagctaa gaatatgtat atttaagtga agtgtgtgtt
    82321 gtaattgttc taaagttatg tagttaaaca ggtttatata caaatagatt tatagataaa
    82381 tatgtagttt agtatatatt tgaataagct ttggggaggt aacatgggga ttggaattga
    82441 atgtaacaaa aaaataaata aaagtattga caaaactaga ataaagaaaa ataatct
//
LOCUS       DAEPHU010000006        81898 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 01A10CD0081
            SAMN05941466-rid12468953.denovo.006, whole genome shotgun sequence.
ACCESSION   DAEPHU010000006 DAEPHU010000000
VERSION     DAEPHU010000006.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941466
            Sequence Read Archive: SRR6291087
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 81898)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 81898)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068158.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 22:43:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,892
            CDSs (total)                      :: 3,805
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 87
            rRNAs                             :: 8, 1, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 55
            CDSs (without protein)            :: 55
            Pseudo Genes (ambiguous residues) :: 0 of 55
            Pseudo Genes (frameshifted)       :: 21 of 55
            Pseudo Genes (incomplete)         :: 28 of 55
            Pseudo Genes (internal stop)      :: 16 of 55
            Pseudo Genes (multiple problems)  :: 8 of 55
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..81898
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941466-rid12468953.denovo.006"
                     /strain="01A10CD0081"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            complement(<1..564)
                     /locus_tag="KR231_000428"
     CDS             complement(<1..564)
                     /locus_tag="KR231_000428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HBH0002845.1"
                     /translation="MKKSVALVNDSRKDLIDFLENNLKLVFGDSININRYFINEINDN
                     DIINDDVILVMSVERLDKIINNILDKKKVIVVRRTFREDKIYNLLSLPQGTNVLIVND
                     SDETTLETISLFYKIGVTNIRPIPYMNDNNYKNIKIAITPGVPEKVPSFISDIFDLGH
                     RYIDISTFIEIINLLQIDSKEIQSNLVK"
     gene            1035..1685
                     /locus_tag="KR231_000429"
     CDS             1035..1685
                     /locus_tag="KR231_000429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cyclic nucleotide-binding domain-containing
                     protein"
                     /protein_id="HBH0002846.1"
                     /translation="MKAEKTSIYPIIKNNLNKISIVEYKKGQRFVASDKDLQEVFFII
                     EGVALVECTTRGGNKFLVDIVPENEFIGKISYIYEHNLKCDIFAKTNIKLFRFEKNVF
                     EEFYLKPDFIALFHRKCTRRIYELYKTRMVRELFSCTEVIAYCISNKQENNVCNIKAI
                     RNFSEIYSISRKSRYHSLLKLTEKEIVKKMGNTYEILNYDELHKLAFEVKEFLEDE"
     gene            complement(1825..3201)
                     /locus_tag="KR231_000430"
     CDS             complement(1825..3201)
                     /locus_tag="KR231_000430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HBH0002847.1"
                     /translation="MQELFSLKDENKRFYKILLSLCIPIIIQNLISTSVNVIDTIMIS
                     SLGETSVASVGVANQFFFLFNMSLSGITGGAGVFISQFYGKKDVSNIRKVTGLTCVLA
                     IVLSFVFVIPALLTPKPIIHIFSYDSEVVKLCIDYFSIAVFSYPLIAVSTVFSTGSRG
                     VRNPKLGMICSAFALVTNVILNYGFIFGNFGLPALGVKGAALATVIARICELILMITY
                     VYLYKKDYILKFGLKNLKAIDKIFIKSFSSKSFPIFVNDSVWAIGTVLYSVAYARAGT
                     SAIAASQIATSTGNFFIMTAVCIASGASIMLGNELGADHIKRAIEYAKKFSILVFSAG
                     LILGIILILNIPLLLKMFSVSDSLASDITKIFFIMGILMALKSFNTLVIIGILRSGGD
                     TKYALFLELGCMWLASIPLTFIAAFKGAPIFVLVLLTYSEEVVKFIFGVPRALSKKWA
                     INIVKEID"
     gene            complement(3217..5130)
                     /locus_tag="KR231_000431"
     CDS             complement(3217..5130)
                     /locus_tag="KR231_000431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HBH0002848.1"
                     /translation="MIVLSCNNLNKSFGIDSILENISFTVNEGDKIGIIGVNGTGKTT
                     LFKIISGIYGYDSGDIYTSKDCEIGYLEQNTNFYSDNTILEEVLEVFKNLIEMESYLR
                     ELEVKISEESTKTNSPIIEKIMDEYSHKLELFSDLNGYGYKSEAKGVLKGLGFSDNDM
                     DKPISILSGGEKTRVLLGKLLLKKPTLLLLDEPTNHLDSEAIEWLEVFLKQYKGTVML
                     ISHDRYFLDQSVNRIFEVHNKKLKVYNGNYSKFVELSKIEKELELKKFEDQQKEIKKQ
                     EESIERLKAYGREKHLKRARSKEKALDKVDVLDKPEAYRKKARIQFTPSVQSGNDVLQ
                     IRDVSMGYGERILFKDLDLDIYRGEKVALIGANGVGKSTLFKIITNELQPLSGNIKFG
                     TNVHVSYFHQEQKTLNLDNTIIDEIWENNTHLTQTTLRNMLGAFLFVDEEVFKKISTL
                     SGGERARVAILKLILSNANLLLLDEPTNHLDIDSKEVLEEALTNYDGTIFTISHDRYF
                     LNTVVDKILVLDENGITEYLGNYDYYIDKKRQIQEMSIIEEKEEKTRTQIKDEKRKER
                     EQREIEKKNRIKRQNIEKEIEKLEIEIEKLDILLCQEEVYSNPDKAKEVSQEKINLEN
                     NLASLYDEWEEFM"
     gene            5266..5898
                     /locus_tag="KR231_000432"
     CDS             5266..5898
                     /locus_tag="KR231_000432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-sensing transcriptional repressor Rex"
                     /protein_id="HBH0002849.1"
                     /translation="MLGNKNISMAVIRRLPKYHRYLGDLLDRDIQRISSKELSDIIGF
                     TASQIRQDLNNFGGFGQQGYGYNVEALHTEIGKILGLDRPYNAVLVGAGNLGQAIANY
                     AGFRKAGFEIKALFDANPRMIGLKIREFEVLDSDTLEDFIKNNNIDIAVLCIPKNGAQ
                     EVINRVVKAGIKGVWNFAPLDLEVPKGVIVENVNLTESLFTLSYLMKEGK"
     gene            6037..6576
                     /locus_tag="KR231_000433"
     CDS             6037..6576
                     /locus_tag="KR231_000433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TraR/DksA C4-type zinc finger protein"
                     /protein_id="HBH0002850.1"
                     /translation="MVFVEELWKKAIEFHGHECPGLAIGFKAALAAKKYLGCKQSGDE
                     EIVCISENDACGIDGIQVVLSCTMGKGNLLLRMTGKSVYHFFNRENGKSIRIYVKSKP
                     FEMDREGYKRYLLESDFEEIFEITDTKLRLPEKARIFKSLKCEVCGEFASEQYIRIEE
                     GKKVCLDCFDKYERFYEEY"
     gene            complement(6752..6922)
                     /locus_tag="KR231_000434"
     CDS             complement(6752..6922)
                     /locus_tag="KR231_000434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004619190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S binding protein"
                     /protein_id="HBH0002851.1"
                     /translation="MAYKITDACISCGACEAECPVSCISAGDDAYVIDAGSCIDCGSC
                     AGACPVDAPQPE"
     gene            7207..8274
                     /locus_tag="KR231_000435"
     CDS             7207..8274
                     /locus_tag="KR231_000435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729218.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CapA family protein"
                     /protein_id="HBH0002852.1"
                     /translation="MKNKLVYICIMSLLLFVVGCSNNPNKESTIKKDSKNNQSQVKEE
                     KREPVKKDITISFAGDVTMGNYKGSSYYGSFDHEFKRQGEDYNYFLKNVKPVFEKDDL
                     TVVNLEGPLTTASNAKEKKFAFKGKPGYVNILKSGSVEAVSIANNHSEDYFEEGMKDT
                     QFILDENKINYFGLGKDAVVDVKGIKVGLLGYNGLSTEYNEKNLKQMEDDIKSLKKKS
                     DVVVVYFHWGIELDYYPDKKQKDFAHYAIDKGADLVMGSHPHVIQGIEKYKNKYIAYS
                     LGNFCFGGNKNPSDTDSYIYQQTFTFSDNKLTSIKEPNIIPTSITSSNSRNNYQPKIL
                     DGSEKDRVLNKLEKISKDLNK"
     gene            8444..10345
                     /gene="cooS"
                     /locus_tag="KR231_000436"
     CDS             8444..10345
                     /gene="cooS"
                     /locus_tag="KR231_000436"
                     /EC_number="1.2.7.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic carbon-monoxide dehydrogenase
                     catalytic subunit"
                     /protein_id="HBH0002853.1"
                     /translation="MACNTCKMCESADKKLESFVASKDVETAFHRTEDQKVKCGFGLQ
                     GVCCRLCSNGPCRVTPKSPRGICGADADTIVARNFLRAVASGAACYLHVVENTAKNLK
                     NVGITKGVVKGEKTLNQLAEMFGIESDEKYDKCIKVADKVINDLYKSRDDKMELVEKI
                     AYAPRVKKWKELGIMPGGAKSEVFDAIVKSSTNLNSDPVDMLVNCLNLGISTGLYGLT
                     LTNLLNDVMLGEPVIRMAPVGFNVIDPDYINIMITGHQHSTFANFQDRLKDEDVIKLA
                     QSVGAKGFKLVGCTCVGQDLQLRGEHYQEVFAGHAGNNFTSEAVLSTGAIDIVLSEFN
                     CTIPGLEPIADKYKVKMVCLDDVAKKANAECIGLDRSKLDELSNTLIEKALESYKERR
                     GSIEIDIPKDHGFEQSLTGVSEKNLKAFLGDSWKPLINLIAEGKIKGVAAVVGCSNMT
                     AGGHDVNTVELTKELIKKDIIVLSAGCSTGGLENVGLMSPGAEELAGENLKEVCKTLG
                     IPPVLNFGPCLAIGRLEIVATELAAELGIDLPQLPLVLSAPQWLEEQALADGAFGLAL
                     GLPLHLALPPFITGGKLVTEVLTEKLKDLTGGHVIVNPDPKSSANQLEEIIIDRRKNL
                     GLKDVECNA"
     gene            10338..10811
                     /locus_tag="KR231_000437"
     CDS             10338..10811
                     /locus_tag="KR231_000437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S dicluster domain-containing protein"
                     /protein_id="HBH0002854.1"
                     /translation="MHRIFINKDLCTGCKSCVLACMLKHNKDYDMYTLDLENIDNDSR
                     GHIELDSRHNNPVPILCRHCDEPECVLACMSGAMHKDSESGIVSYDEEKCGSCYMCVM
                     SCPYGLLKPDDRSKQNILKCDLCKDEEYPRCVANCPSGAIELQKEENDELCSVRG"
     gene            10786..12012
                     /locus_tag="KR231_000438"
     CDS             10786..12012
                     /locus_tag="KR231_000438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HBH0002855.1"
                     /translation="MNYVVLGASAAGINAVKTLRELDKDSNIVVISKDENVYSRCMLH
                     HVISEHRTLKQINFVDEDFMEQNNVKWIAGKTVKGIDINKKVVQTEDITVNYDKLLIA
                     TGASSAIPPIKNLRDGNFVYSVRNIDDIYKIKEKAQNSKNVVIIGAGLVGIDALVGLF
                     KYEQLNISVAFMEKYILDRQLDEYTASVYENKFKEKGVKFYPSASIQEIVLDNSKNVT
                     GVAFSNGEVLDADMVIVATGVKPNADFLDGTGIEYDRGIIIDDMCQTTQKDIYAAGDV
                     VGKNAIWPLAVKQGIVAAYNMVGKDKKIEDEFAFKNSMNFMDIPTISIGMNTPVDDSY
                     KVLTRHGINDYKKFVFKDNVIYGAVIQGDISYVGVLTYLIKNKVEIYDLENRIFDICY
                     ADFFNIKENGEFCYSV"
     gene            complement(12151..13338)
                     /locus_tag="KR231_000439"
     CDS             complement(12151..13338)
                     /locus_tag="KR231_000439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HBH0002856.1"
                     /translation="MNITKNFLKDYLEKFGETPFLVRLKDEEEFLIGEGSPQFKVIVN
                     NDISKSELLKSTSLALGEAYINRDIEVEGDLFLTLNLLLKQIDKFNIDNSAVKHLLHS
                     SNSMRHQKKEIHAHYDIGNDFYSLWLDKTLSYSCAYFRNDNDTLYDAQVNKVHHILTK
                     LNLEEGMSLLDIGCGWGFLLIEAAKKYKIHGVGITLSEEQFKEFNARIKEENLQDYLE
                     VRLMDYRELKKSDLMFDRVVSVGMLEHVGRENYELFIKNVNAVLKDGGLFLLHYISGL
                     QESYGDPWIKKYIFPGGVIPSLREMIHICSDYKYHTIDVESLRLHYVKTLLYWQKNFS
                     ENLPKIKEMFDDKFIRMWDLYLCSCAAAFNTGIIDIHQILFTKGIKNDLPLTREYMYN
                     CSK"
     gene            13611..14435
                     /locus_tag="KR231_000440"
     CDS             13611..14435
                     /locus_tag="KR231_000440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729220.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATPase"
                     /protein_id="HBH0002857.1"
                     /translation="MEVYALVGSSGTGKSFKALEFAYENDIEYIIDDGILIYKNKVLA
                     GISAKQANTTIEAVKRAIFYNLEHRQEVREAIKKENIRKILIIGTSKKMVNQIVERLS
                     IGRVCKFINIQDISTKYEIEIAKQARKEGNHVIPVPAVEIKSMASGLSINSLKRLFRK
                     GNNRNMVVLEKTIIRPTFSYIGKFYISADVIKQIIEYEVYNFGSIDRINKINIENCNN
                     FMNIFVSININDLETIKKIEDIQQTIKKSIEKMTLVNVQKIDINIHKIKKINFLQC"
     gene            14564..15829
                     /gene="gluD"
                     /locus_tag="KR231_000441"
     CDS             14564..15829
                     /gene="gluD"
                     /locus_tag="KR231_000441"
                     /EC_number="1.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-specific glutamate dehydrogenase"
                     /protein_id="HBH0002858.1"
                     /translation="MSGKDVNVFEMAQSQVKNACDKLGMEPAVYELLKEPMRVIEVSI
                     PVKMDDGSIKTFKGFRSQHNDAVGPTKGGIRFHQNVSRDEVKALSIWMTFKCSVTGIP
                     YGGGKGGIIVDPSTLSQGELERLSRGYIDGIYKLIGEKVDVPAPDVNTNGQIMSWMVD
                     EYNKLTGQSSIGVITGKPVEFGGSLGRTAATGFGVAVTAREAAAKLGIDMKKAKIAVQ
                     GIGNVGSYTVLNCEKLGGTVVAMAEWCKSEGSYAIYNENGLDGQAMLDYMKEHGNLLN
                     FPGAKRISLEEFWASDVDIVIPAALENSITKEVAESIKAKLVCEAANGPTTPEADEVF
                     AERGIVLTPDILTNAGGVTVSYFEWVQNLYGYYWSEEEVEQKEEIAMVKAFESIWKIK
                     EEYNVTMREAAYMHSIKKVAEAMKLRGWY"
     gene            16042..16632
                     /locus_tag="KR231_000442"
     CDS             16042..16632
                     /locus_tag="KR231_000442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase M56"
                     /protein_id="HBH0002859.1"
                     /translation="MHFKSKDLNLKYLVLFLKIVYWFNPFICIMEKYMDLDCELYCDE
                     RVLKNCTVQQKQEYALTIVNSMKRSTNFSNKFVAGLNKQSDIRKRVINMFSEKHKNGI
                     LRALIISLFSSITFFKFDSTSIIEENDFLERSRYTFEGRQEDMFVTIDFIYADVPIKL
                     RKEHEENCRVNGIVPKDSDSIEIIPRFYKDCMDLKK"
     gene            16962..18095
                     /locus_tag="KR231_000443"
     CDS             16962..18095
                     /locus_tag="KR231_000443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase M56"
                     /protein_id="HBH0002860.1"
                     /translation="MSNFILNGIFRTVIVSSLSILLILIFKKNVFKRFSKKFNYYIWM
                     IVVIKLFLPFTYYTFTINILRSKKHININNINLEGFNNVSTISNNIILYTWIITVVVY
                     LIYTIFKYIKLKNLINDLSYDVDDREIVNLYKNILEEFNITKDIKLKYSYEVETPAFF
                     NSCVLLPPHEYKLKELDWIFRHELMHFKSRDLYLKYVILFLKTVYWFNPFIYIMDKHI
                     DLDCELYCDERVLKNRNSEEKKDYALTILNAMRKGSNTSNKFIAGLHKQSDIKKRVMN
                     MFNEKYKNGILMALTLCLLSSITFLKVNSTSIVNLNVLPKGFEDLRTVSSIRFSVIGF
                     TYADAPKNMREEYKINCESLGLIPKDSDKIEVGIEYYDSLLND"
     gene            19011..20033
                     /locus_tag="KR231_000444"
     CDS             19011..20033
                     /locus_tag="KR231_000444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C40 family peptidase"
                     /protein_id="HBH0002861.1"
                     /translation="MKKKILIPVFASVMALSVSSIVNADEVNDSSQNKDDKTNTELNL
                     GEYKEVKYKVAKIKDGVAIKIREEGQVQNIAYSGDEFTVLGTQGEWVKVKVEDGEGWL
                     ATRYVDISEGVGYTNADKVNLRKDKSESSEVIEELEKGSSLLVLEDNGDWLKVKDGET
                     EGYVKSSYISDKAPVIEEPQVNPSIDQNVDSTNNNQQNNANTNQQNNNSNVPTANSNA
                     VQAVLNLAYSKQGCPYVWGAEGPNTFDCSGFTQYVYRNAVGKNIPRTSKAQSKYGQTV
                     SKANLQPGDLVFFTTNGSGSVSHVGIYVGGGNMIHSPSTGKTVSVTSINSSYYTARFV
                     TAKRIL"
     gene            20330..21250
                     /gene="pyrB"
                     /locus_tag="KR231_000445"
     CDS             20330..21250
                     /gene="pyrB"
                     /locus_tag="KR231_000445"
                     /EC_number="2.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate carbamoyltransferase"
                     /protein_id="HBH0002862.1"
                     /translation="MLKSRNLIQPEDFSIEEIDEILELAQKIIDNPSKYSRICEGKLL
                     ATLFYEPSTRTRLSFESAMNRLGGRVVGFSEPNSSSASKGETLGDTMRIVSGYVDIIA
                     MRHPQSGAASEAARYTEVPFINAGDGKNQHPTQTLTDLLTIKSLKGTLESHTIGLCGD
                     LKYGRTVHSLVKAMARYKNTKFVFIAPEELKMPDYIKEAIKGHAYYETNNLDDVIGSL
                     DVLYMTRVQQERFEDKSEYERLKNYYILNKAKLEKASKDMLVMHPLPRVNEIDIDVDS
                     DDRAVYFKQAKYGMYVRMALIIKLLGINED"
     gene            21289..21981
                     /locus_tag="KR231_000446"
     CDS             21289..21981
                     /locus_tag="KR231_000446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase electron transfer
                     subunit"
                     /protein_id="HBH0002863.1"
                     /translation="MYKILENIYIGEDMYRMKVKGNFEGKMGQFYMLRAWDTYPVLSR
                     PISIHDIDEEGITFLYKVVGEGTQILSNLKVNDTIKLEGPYGNGYAKVDGKVALVGGG
                     IGVAPLYLVAKNIKNCDAYLGFREDVILEDEYKQVCNKVYTTVGNTFVTDIIDVEKYD
                     YILTCGPTPMMEKLVKMVEGTKTRIMVSLENHMACGVGACLVCTCKTNGGNKKTCKDG
                     PVFWGEDVIFNG"
     gene            21974..22876
                     /locus_tag="KR231_000447"
     CDS             21974..22876
                     /locus_tag="KR231_000447"
                     /EC_number="1.3.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase"
                     /protein_id="HBH0002864.1"
                     /translation="MGNLSVKFGSVEFKNPVIMASGTFGFGKEYNEIYDIQKLGGISS
                     KGLTLNKKPGNNGMRVHETPSGMMNSVGLENPGVQGFIDYELPFFSKLDLVRIANVGG
                     GTLEDYLLGVQMLNDKPIDIIELNISCPNVKAGGMAFGIKNEVAREVVREVRNITKLP
                     LVIKLSPNAEDIVGMAKVCEEEGADGVSLVNTFKAMAIDIKNRRPVFENVYAGLSGPA
                     IKPIALRMVHEVCKNVNIPVMGMGGITKATDAIEFIMAGATCIQVGTANFMNPRIGIE
                     IIDGINEFMDREGIKSLDEIRGII"
     gene            22961..23545
                     /locus_tag="KR231_000448"
     CDS             22961..23545
                     /locus_tag="KR231_000448"
                     /EC_number="2.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="orotate phosphoribosyltransferase"
                     /protein_id="HBH0002865.1"
                     /translation="MSKVDVVDILKKSDALLEGHFLLSSGKHSNRYVQCAKVLRFPEY
                     AAEVLSTVVEQIKDLDIDLVVGPAMGGVIVSYELGRQLGKEAVFTERKDNTMELRRGF
                     EVKKGAKIIIAEDVVTTGKSTMETKRVLEALGGEVVGVACIADRTNHDIGMPIYSAIK
                     LDIQVYESDECPLCKEGKLPVVKPGSREFKELGM"
     gene            23760..24686
                     /locus_tag="KR231_000449"
     CDS             23760..24686
                     /locus_tag="KR231_000449"
                     /EC_number="1.1.1.169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-dehydropantoate 2-reductase"
                     /protein_id="HBH0002866.1"
                     /translation="MKNQLNENHKKVVFFGVGAVGATFAEQFFNSKYDFKILCDNERK
                     KRYLEEGFIINGKRYDFDYVTKDEYKQEADFIIIGLKYNNLKENIKELDGLVGKNTVI
                     MSLLNGVDSEEIIGERFGIEKMVYSYVTNIDAKKINNNIIHTTNGIIVFGNKDNSEDR
                     KTNIITEVFDDVNIEYTLSKDIQRDMWWKYMVNIGVNQTSAILGAPYGVFQSSEHLRE
                     LAKSAMREVVAIAQAKDISLTEDDVEHSLHRILEHSKEGRTSMLQDVEAHRLTEVDMF
                     SKNICKLGKKYNIPTPINQTFFYMIKVIESRF"
     gene            complement(24738..25628)
                     /locus_tag="KR231_000450"
     CDS             complement(24738..25628)
                     /locus_tag="KR231_000450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HBH0002867.1"
                     /translation="MFEELKTFVAVVEYKNFTKAGEYLNLSQPSVSKHIKNLENYFKV
                     VLINRSIKQKTIFITESGQILYKRAKEILNLLNITYHDVSQVSDAITGHLKIGASLTI
                     GEYILPNFLALFSKKYPDIDVEVFIKNTSIVSSHVKDYILDIGLIEGTCSSPSFIQEY
                     FFEDKMVLALPYKSHLLKDFSFDKLQNQKWIVREDGSGTRDYLDMFLSVKEIIPKSMM
                     VFGSNYAVKESVRNNLGITIVSNLVTSLPVLNNELSVIELGSSYNRHFSYIFPKDITL
                     SKAATIFIEELKIFSNLNSI"
     gene            25816..26847
                     /locus_tag="KR231_000451"
     CDS             25816..26847
                     /locus_tag="KR231_000451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative sulfate exporter family transporter"
                     /protein_id="HBH0002868.1"
                     /translation="MLKKKSSLTLKTIREILPGLFVSVLVGYISIFISILIPKVGAAS
                     ISIFLGMFVGNLFLNQKVFQKGYKFSETDLLSYSIVLLGATLSVSTLIDLKVSGILFI
                     ILQMTITIIAALYIGKKLGFEENFRFLMASGNAVCGSSAIGATVPVVNATDKEKGIAV
                     TIVNVTGIFLMFLLPIISQFLYSHELVKTSAMIGGTLQSIGQVVASGAIVGENVKDLA
                     TIFKIVRVIFLVVVVLVFGHMKNQSNREILEEEKDEIKKKKVTIPWYVIGFFITCALF
                     SMNIIPQEVSVLCKEISNKLEIIALAAIGLKVNVKDLVKQGKEVSLYGLFVGIVQVVS
                     AVVLIKIFI"
     gene            27141..28016
                     /locus_tag="KR231_000452"
     CDS             27141..28016
                     /locus_tag="KR231_000452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA glycosylase"
                     /protein_id="HBH0002869.1"
                     /translation="MNVYEKGNGVILEGVTDFDPVHIFECGQCFRWHKQEDGSYTGVA
                     KGRILNVKKENDKIYLNNTNLKEFNSIWYNYFDLGTDYTEIKNKLKNMDEYLNKATEF
                     GWGIRILRQDGWEMLISFIISSNNRIPMIQRAIENLSRKFGKYIGEYEGNEYYAFPTP
                     EELNKASQEEIRACQTGFRDKYIKSTTQAVIENNDEVSEYTNLSTEDCRKELLKFNGV
                     GPKVCDCIALFGMQKYDSFPVDVWVKRVMQEFYIDEDMSLPKMRTYGIDKFKEMSGFA
                     QQYLFYYARELGIGK"
     gene            28034..29524
                     /gene="cls"
                     /locus_tag="KR231_000453"
     CDS             28034..29524
                     /gene="cls"
                     /locus_tag="KR231_000453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cardiolipin synthase"
                     /protein_id="HBH0002870.1"
                     /translation="MGVIGTIFLFYLIISYLAGAIISVIILLENRDPAKTMSWLLMFI
                     IFPGVGLMIYAISGRNIRKRKLFKTQKLANNIKEKKLFDTLEKITEIVELEKESIKQN
                     KLLRDEEDGSYRKRVINMLLKTGMFPFTKNNKVDVFVDGNEKFKRLIEDIREAKDHIH
                     LEYFIIKDSEIGRVLKEELIKKAKEGIKIRILYDDVGCWRFWFNRKFFREMREVGIEI
                     AAFLPTKFPIIGGKLNYRNHRKIVVIDGIIGYTGGINIGDEYLGKNDKFGYWRDTHIR
                     IKGISVYMLQMTFLIDWYYTTKEVLVTKNYFPSVGNVGESMIQVVASGPDSDWEDIHY
                     AYFSAICQARKNVYIETPYFIPDESLLKAIKSAALSGVDVRIIFPKIADHKIVNIASY
                     SYFEEILRAGGKVYLYNKGFIHSKVVIIDDKIASAGTANMDLRSFMLNFEVNAFIYDE
                     EVIRVMTDDFFEDLSHCEELNLEVFKNRNIIQKIKESVARLFSPIL"
     gene            29717..30001
                     /locus_tag="KR231_000454"
     CDS             29717..30001
                     /locus_tag="KR231_000454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012062101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="co-chaperone GroES"
                     /protein_id="HBH0002871.1"
                     /translation="MKIRPLADRVVIKKVEAEEKTASGIVLPGAAKEQPQIAEVVEVG
                     PGGIVEGKEIKMELTVGDKVIFQKYSGTEVKIEGQEYTILRQSDVLAVIE"
     gene            30034..31662
                     /gene="groL"
                     /locus_tag="KR231_000455"
     CDS             30034..31662
                     /gene="groL"
                     /locus_tag="KR231_000455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729227.1"
                     /note="60 kDa chaperone family; promotes refolding of
                     misfolded polypeptides especially under stressful
                     conditions; forms two stacked rings of heptamers to form a
                     barrel-shaped 14mer; ends can be capped by GroES;
                     misfolded proteins enter the barrel where they are
                     refolded when GroES binds; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chaperonin GroEL"
                     /protein_id="HBH0002872.1"
                     /translation="MAKEIKFSEETRRALEAGVNKLADTVKVTLGPKGRNVILDKKFG
                     SPLITNDGVTIAKEIELEDRFENMGAQLVKEVATKTNDVAGDGTTTATVLAQAIIREG
                     LKNVTAGANPILLRKGIQKAVTVAVEELKNQSRIVETQEAISQVASISAGDEEVGKLI
                     AEAMEIVGKDGVITVEESQTMNTELDAVEGMQFDRGFVSAYMVTDVDKMEAVLNDPYI
                     LITDKKISNIQELLPVLEQIVQQGKKLLIIAEDVEGEALSTLVVNKLRGTFDVVAVKA
                     PGFGDRRKEMLQDIAILTGAQVISEELGYDLKEADLSMLGRASSVKVTKESTTIVDGS
                     GDKKAIEDRVTQIKHQVEQTTSDFDREKLMERLAKLAGGVAVVKVGAATEVELKERKL
                     RIEDALNATRAAVEEGIVAGGGTAFVSVIPAIGTLIESLEGEVKLGAQIVKKALEEPL
                     RQIAINAGLEGAVIVQNVVNSEAETGFDALNEKYVNMIEAGIVDPTKVSRSALQNAAS
                     IASTFLTTEAAVADLPEKEDVGMPGMGGGMPGMM"
     gene            31924..32664
                     /gene="larB"
                     /locus_tag="KR231_000456"
     CDS             31924..32664
                     /gene="larB"
                     /locus_tag="KR231_000456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nickel pincer cofactor biosynthesis protein
                     LarB"
                     /protein_id="HBH0002873.1"
                     /translation="MDLRKLLEEVKNENIDIDFALEKLKDLPYEDLGYANIDHHRELR
                     NGYPEVIYCEGKSDEHILGIIDKMNQKSSNILGTRCRKETFLKIKEIYNHAEYEEASK
                     ILKIQNHDIENIGKGKIVIATGGTSDIPVADEAYHTAKFLGNDVDRIYDVGVAGIHRL
                     LNKRHKIDSARVIVAVAGMEGALASVIGGLVDVPVIAVPTSVGYGANFGGLAALLAML
                     NSCASGISVVNIDNGFGAGYLASMINKL"
     gene            32748..33482
                     /gene="larC"
                     /locus_tag="KR231_000457"
     CDS             32748..33482
                     /gene="larC"
                     /locus_tag="KR231_000457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nickel pincer cofactor biosynthesis protein
                     LarC"
                     /protein_id="HBH0002874.1"
                     /translation="MSEKILYFDIISGISGDMTLASLLNLGVPKEIFLEEIHKLRMSD
                     EFNINISSKTENGIVGTKVEVITKEKHTHRNLVDIFEVIDKSTLNENVKSKAKKIFMV
                     IGEAEAKVHGTTIDKIHFHEVGAIDSIVDIVGASILVDLLCVDKVCASTVSVGSGFVK
                     CEHGIIPIPAPATIEILKGVPIKLNNVNGECTTPTGAAIIKVLCDEFVDELEFSPKQI
                     GYGIGHKKFEVPNILRTVLGEKKKKN"
     gene            33512..33931
                     /locus_tag="KR231_000458"
     CDS             33512..33931
                     /locus_tag="KR231_000458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF111 family protein"
                     /protein_id="HBH0002875.1"
                     /translation="MSSEIYSYLYEKILDEKALDIYTESIYMKKNRPATKVSILCNES
                     DLEKFIKILLLETSTFGVRYNAYNREILERKFVKLDTKYGVVTVKLGYYKGKLVKATP
                     EYNECKTIAKNEDIPIKKVFADINFRIKEEFSENLLT"
     regulatory      33991..34092
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00167"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="purine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="guanine and/or adenine"
                     /db_xref="RFAM:RF00167"
     gene            34313..35848
                     /gene="guaA"
                     /locus_tag="KR231_000459"
     CDS             34313..35848
                     /gene="guaA"
                     /locus_tag="KR231_000459"
                     /EC_number="6.3.5.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000743900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing GMP synthase"
                     /protein_id="HBH0002876.1"
                     /translation="MKHELVLVIDFGGQYNQLIARRVRENNVYCEILPCTASIERIKE
                     KNPKGIIFTGGPNSAYLEDSPTISKEIFELGVPILGICYGIQIMSHVLGGVVRKGNKQ
                     EKEYGKTAITYGKSSLFEGITTNSVWMSHTDLIEKVPEGFTIVANTNDCPVAAMENVE
                     RNLYGVQFHPEVEHCLEGDKILTNFLYNICKVKGDWTTDSFIEDKIKELKEKIGDKKA
                     LCALSGGVDSSVAAVLIHKAIGDNLTCIFVDHGLLRKNEGNDVERIFREKFDINLIRV
                     NAEDRFLSKLKGVSEPEAKRKIIGEEFIRVFEEESNKLGKMDFLVQGTIYPDVIESGH
                     GNAATIKSHHNVGGIPEDVDFQEIVEPLRELFKDEVRKIGLELGIEEGLIFRHPFPGP
                     GLGIRVIGDVTKEKCDILREADAVYMDELRKAGLYREIWQAFATLPDVKTVGVMGDER
                     TYAYLVGLRAVTSSDGMTSDWYKMPYDVLERISNRIINEVDGVNRVVYDITSKPPGTI
                     EWE"
     gene            36387..37817
                     /locus_tag="KR231_000460"
     CDS             36387..37817
                     /locus_tag="KR231_000460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HBH0002877.1"
                     /translation="MILNQIFIEAGGIMRNKIIIGITFSLVLLMSGCASKQTAEINVL
                     ATTDLHGVIPYELTSYVKEERKKDKNLTLVDAGDFFDSGEVFGSSMDSYFSARYKDGD
                     NNTESYIETPISKDMKEVGYDVAVLGNHEFISNNKFYLDNMISDFEKQKINILSANTY
                     KKNGDSYTKPYIIKNINTPEGNVKLGILGLTIKEVGERKQWKDGKLVDSKSLELKDQE
                     GYNGELYMNDLVEDAKKWVGIMEKEKPDIIVAVAHTGEKPKKPKNPGNRIQDLAQQVD
                     GIDAIVAGHNHVQIEQHDYKNKSGENVIVTEPGKHGECISKINFKLEKNNDKWNIVDK
                     SSKLIKFEKNQESDKFGEFISSINKVSKDKKEIRLSEVKTPEWDKIYVFKSGTSADDI
                     YKTIGYKWRNISSPKGDDMVQIVVMNNNKPVSYVYGEAEVMPINIKCDESEYKDNVVT
                     IYPNKNDKFKIEKGKQEYSINLKHIQ"
     gene            complement(37965..38315)
                     /locus_tag="KR231_000461"
                     /pseudo
     CDS             complement(37965..38315)
                     /locus_tag="KR231_000461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009904812.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
     gene            38310..38831
                     /locus_tag="KR231_000462"
     CDS             38310..38831
                     /locus_tag="KR231_000462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromate transporter"
                     /protein_id="HBH0002878.1"
                     /translation="MFSIGGGYAIILLIQEKVVNQTGWISEKMFTDIITISQMTPGPL
                     AVNTSTFVGLQIGGFWGAVAATLGCVLCGVVISLFLYNFFQKHQNSTYIFEILNGLKS
                     ASLGLIISAAATIIILALFGTNKVYFNSIFEMLNWTALIIFFVTLLIVRKWKINPIVI
                     IIISGILGIFFYL"
     gene            complement(38960..39754)
                     /locus_tag="KR231_000463"
     CDS             complement(38960..39754)
                     /locus_tag="KR231_000463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HBH0002879.1"
                     /translation="MIFCNSFITRKSSMNIVVTHTPIVTTLEMQKAYEPLAKHNVNIF
                     AFDFSGTGKSDGYEKDFSRNSIVKDLDSVITYIEKNYSSNIHLYGNTGIGGMFAQYYA
                     CSDNKLKSFAQFACVDYKNTTGVGYTYLTVKLLNFFFKFLPNFHITVKPPKYKGYNEV
                     YDNEFYKIFEKKNPHIWKNSTKIINTMLECFIAKDSKIKDGVNIPTLVFKTLHDRYFK
                     TQYFDSYYNSLKCKKKLVEINNVHNSYYIDSEKFCQEAYDWFVENQ"
     gene            complement(39978..43406)
                     /gene="uvrA"
                     /locus_tag="KR231_000464"
     CDS             complement(39978..43406)
                     /gene="uvrA"
                     /locus_tag="KR231_000464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrA"
                     /protein_id="HBH0002880.1"
                     /translation="MKINNYKNQSIITNPKKFENKYQDLPKTPIELLKVVQSLVIHGD
                     QGKLYGISFNKQQSDEELLRTIPQMLKRIFEINSNPLTIPRNPKQRLVGMCRDYSLLL
                     VSLLRYRGFEARMRAGFANYFESELTYEDHWLVEYYDTLTKRWIRIDAQIDDIQKNYF
                     QINFDTHDVGKTDGFLTGSEAWIRCRQGHAHQDDFGYNKNWKGWHSVKGNLLHDFNNM
                     IGLELLPWDLWTELSSKKYNQLTRAEKNLLDEMAEILSSGNIKIEDLNLLIEKLPEDY
                     LKSIFSQLKILGISEIKELGNPLELEKKFKFTKSINKSIKNSLCHNKSSIYLKGGRQN
                     NLKDVEVTIPKNQITVITGVSGSGKSSLAFDTIYEEGKRRYFENLSNGAKLSEQLQKP
                     EFDLLQGLTPTIAIEQKKGSQNPRSTVGTLTSIWDYLRMLFVSIGKSYCPYCKIPLEK
                     KNNTKNYCPHCQTIFSKINTSTFNANSHTGACHDCNGLGFTYQVNPQLIVKDPTISIL
                     DGATYYFGKLKGKKPNGNWMVGELYAIAKDKNIDLDIPWNELPRDFIDAILYGTDDKI
                     YEFSFESKGRESKIRRPASGAINHIQRLFRESSSENNTLHQYMNKIPCNTCGGELLCI
                     EARFTTIKGYRFPELTKMTIEQLWNWLCELPNQLQKNELSLVNDILTELKIRVSYLLK
                     VGLSYISTDRTAPTLSGGELQRVRLSSQLGSELVGLTYILDEPSIGLHPRDHNLIIKM
                     IEELRDKGNTVIVVEHDKDTILSADYIIDVGPSAGTKGGFIIAEGTTQEIIKNPNSIT
                     GKYLSTYNKISSQNKIIPSKWLSLKGCHANNLKNIDVEIPLNCMCSITGVSGSGKSSL
                     VFHSLLPALEEKLKQKSIPDKNYTEFTGFDAIDDFILMDQTPIGKSSRSTPATYINIF
                     DEIRSLFAETPQAKQKLLDESYFSFNSKKGQCPNCQGLGKTKIILQYMADQWVTCSEC
                     QGKRYQKEILSIQYKGKTIADILDMEVAEAKTFFSDCSDIYRKLSLLDEVGLGYLKLG
                     QNTLGLSGGESQRIKLAKELGTKTKKRMLYILDEPTTGLHFKDIENLLITFRKLVNEQ
                     HSLLIIEHNTEVIRASDWIIDIGPDSGINGGEIVASGTPDEIKINPNSITGHFI"
     gene            43725..45959
                     /locus_tag="KR231_000465"
     CDS             43725..45959
                     /locus_tag="KR231_000465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729234.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GGDEF domain-containing protein"
                     /protein_id="HBH0002881.1"
                     /translation="MKLSRYKKNSLVLSIILCSLIISILVITVFNTVKLHNISNKQSK
                     NYLNDVSTQIVMNVDSKIKFILSDLRIMADFIKQYEGDSRYEYLSKRKTSYKYYDVGI
                     IDLEGKAEFLSGKKFDLKNTVSYKKGIEGKEYSEVIESMGFVLYSVPIFNDNHEVSSI
                     LIGVSNKESMNEILNIDNFNGKGTIEIINSKGKPLFIGKNTELIKDLSHKYKSSGDEP
                     WAQKMLEDFKNDKSGNITITSSKGVQCLLTYHPITRGLNDWHFLLIVPEDAVLGELNK
                     LNSFTITMTFIITCIIGIITLILYIIRRKYVNQIENIAYLDSITNGINSTKFSMLVKP
                     LISESPDSTYMMIAMNIKDFKLINDCFGSEKGNMTLKHLYNILYKNIDENEEFVCRHD
                     ADLFYLLIKNRPVLEALELLYKIEADTNYFNKNRENPYFLRLSVGIYTIENHNEDLIT
                     IQDHANTARKSFNKTHQSDFSFYSDIERKRLISEKEISNLMEKALENKEFFMCLQPKI
                     DIKSGKISGAESLVRWKNSEKGIIYPSDFIPLFEKSGFICKLDLYILEETCKLISKWI
                     KEGKEVLRISVNVSRQHLNDKLFLEKYKHICNKYNVPTCLIDLELTESIFLENPEAID
                     IIEDIHSNGFKCSIDDFGFGYSSLGILKDFKVDIIKLDRSFFVSKNNIDRGKVVIKSI
                     IELSKRLGMKVTAEGIEELEQVEFLKNVGCDYIQGYVFSKPLLISDFENFAYENNKIK
                     NIHY"
     gene            46215..48245
                     /locus_tag="KR231_000466"
     CDS             46215..48245
                     /locus_tag="KR231_000466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBH0002882.1"
                     /translation="MISGRMLLIMNFLKGKNKTSYKDISKQLSIEERKVRYDINNLNI
                     VLRSLNKSVIQKMNKGVLIIPDDFQVVCINNNEYVFSLTERVSIMKIISMFKIDNLNL
                     EKLSKEFQVSRSSIKNDLNVLSSELERNQITITYDKSFKISGEEDIIYKQRLNILKSY
                     SYLFGKEKSDLSVFEKYLVNVIEKIFKGIYLIDIYNWSMNLLLQMGWTLNDESFTWYV
                     SNIFLFTWYIHSDEKHPLESASLSEPCFENKFDQEFETIIQKKLTKEQIFLLKSFVFF
                     TNKYASLNEDMDLISTEIIVQDLIYNMSEILEISFKEDMILYKGLLNHIAPLIERIKQ
                     NIQIYEELLHVIPDKYQYVLEATKVSIQKNRVLSQIKNENETILLAIHFLGSIHRNER
                     NNYKNILLVCGFGYGVIAMLKDSLVNDYQINIVESIPSYKLQDYKDWESIDFIITTSK
                     IVIDLPKTIIEINPFLQEEDYLKFEEKGIKRKNVLTNYMSIKKRLDFLEEDAQKRVLS
                     IICQELGYSDERILFRQLNLSDLIGIDTIRIIDGDMKWEDAVKFSSNILANCDFVSAQ
                     YAENIIDILKNVGFYAVKDNEFALLHGNDSSLVKVSSISLLICKEAVSFGDKKVKIIF
                     CLASRDKKEQIPAIINLTKMVYKTNFIAMLESAKTKEEAEVLIHKYEKEVTV"
     gene            48242..48694
                     /locus_tag="KR231_000467"
     CDS             48242..48694
                     /locus_tag="KR231_000467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBH0002883.1"
                     /translation="MNKLVNVKCSFKIHVNSKEEAIISLVDVVSKEGYLIDKNQFLKD
                     VLKREETLSTYIGHGIGLPHSQSVGVKNSCITIGKLDTPIEWTEEGEKVDLIFLISVT
                     KDNENNLHLKILSKLARLLMHESFRNQIRCSDEQTVYNLIKEKIEEED"
     gene            48696..49751
                     /locus_tag="KR231_000468"
     CDS             48696..49751
                     /locus_tag="KR231_000468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit EIIC"
                     /protein_id="HBH0002884.1"
                     /translation="MRILKFLQKHLMTATSYMIPFVVAGGILFALSVTLSGQAAVPET
                     GWLAKLNQIGAAGLALFIPILGGYIAFSMADKPGLAPGMIGAYLAKEVNAGFIGGIIA
                     GFIAGFVVLQLKKIKLAPTMRTLGSIFIYPLVGTLITGGIIVFLIGEPIASFMTWMTN
                     WLNGMSGVSKIPLGGILGGMIASDMGGPINKVAATFAQTQVDTLPYLMGGVGVAICIP
                     PIGLGLATLLFPKKFSKEERDSGKASLLMGCVGITEGAIPFATSDPVRVIPCIMAGSI
                     VGNIMAFLLGCLNHAPWGGLIVLPVVDNRLGYIASVLTGAVVVAVLMKLVKKDVKEDE
                     EIEEDLDESIELIFEEL"
     gene            49818..50126
                     /locus_tag="KR231_000469"
     CDS             49818..50126
                     /locus_tag="KR231_000469"
                     /EC_number="2.7.1.202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose-like transporter subunit IIB"
                     /protein_id="HBH0002885.1"
                     /translation="MKIVAVTSCPSGVAHTYMSAESLELSAKKFGIEIKVETQGSSGI
                     DNELSLKDIDEATCVILTNDVEIRNMERFKGKKVVRMSVSEIIKKSDALIKKIKDTFQ
                     "
     gene            50230..51495
                     /locus_tag="KR231_000470"
     CDS             50230..51495
                     /locus_tag="KR231_000470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class II D-tagatose-bisphosphate aldolase,
                     non-catalytic subunit"
                     /protein_id="HBH0002886.1"
                     /translation="MKKLPIKTVVQRLLNLQEEGKSATLLGIGPMSPNLLQASFELAK
                     DDDFPLMFIASRNQVDADELGGGYVNGWNQETFTKDIKKVADKVGFDGLYYLCRDHGG
                     PWQRDKERNDHLPVDEAMELGKKSYLADIEAGFDLLMIDPTKDPFEIGKVIPLDVVLE
                     RTVELIEYCENERKRLNLPDIGYEVGTEETNGGLTSTETYETFITRLKVELDNRGLPM
                     PTFIVGQTGTLTRKTEQVGTFNFRNAYDLAQMAKKYGVGLKEHNGDYLDDVTLLEHIP
                     SQIIATNVAPQYGTEETRAYLKLAEVECKLEKEGLVEKTSNIRHVLLVNAIECGRWRK
                     WVVGEQKNLTTEEIFKDEVLSNEILDIAGHYTFNNDDVKKEIEVLYDNLSKNNIDGQR
                     FVVDHIKRPLRDYAECYNLKGVTTRILNK"
     gene            51583..52299
                     /locus_tag="KR231_000471"
     CDS             51583..52299
                     /locus_tag="KR231_000471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HBH0002887.1"
                     /translation="MINLIFDVDDTLYNQLTPFYTAYNKVFSSIKDISIEDLYMSSRK
                     YSDEVFHMTENGEMPIKEMHIYRIMKAFEELGNSITEKDAQSFQDEYIYQQSQITLIP
                     EVERILNFSKERNINLGIITNGPSNHQRMKLKQLNIENWVDKSNIFISSEVGFSKPDT
                     NIFRVAENVMNLDRENTYYVGDSYRNDVLGAKKAGWKSIWLNHRGHEVEELFYKPDFV
                     ILEHKDLISLFIKICSYKNM"
     gene            complement(52494..52787)
                     /locus_tag="KR231_000472"
     CDS             complement(52494..52787)
                     /locus_tag="KR231_000472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="spore coat protein"
                     /protein_id="HBH0002888.1"
                     /translation="MRNMIENLIKNNTYIDDKVIMLSMLSSAKASANMYLNSALTSST
                     PELRAIYSASLTQMVEGHTALTELSINKGWVKPYDKPIQQLTCSYKESQNVID"
     gene            complement(52793..53008)
                     /locus_tag="KR231_000473"
     CDS             complement(52793..53008)
                     /locus_tag="KR231_000473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0002889.1"
                     /translation="MRILSETEKISLAAVIKMESDGLLMQRAINMLISDEDLKRQSES
                     SILATEGRIKAMQQFIVENEILISEEV"
     gene            53457..53855
                     /gene="tnpA"
                     /locus_tag="KR231_000474"
     CDS             53457..53855
                     /gene="tnpA"
                     /locus_tag="KR231_000474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011291581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605 family transposase"
                     /protein_id="HBH0002890.1"
                     /translation="MYKSNKNIVYDCKYHIVFCPKYRKPVLVGEVEKMLKEILPYKAD
                     ELGAEIIEMETDKEHVHLLISCDPQYGIHKVVKGLKGFSSRVLRENFPHLKSSMPSMW
                     TNSYFVGTVGSVSLEVVKQYIENQQVRTKK"
     gene            53852..55015
                     /locus_tag="KR231_000475"
     CDS             53852..55015
                     /locus_tag="KR231_000475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HBH0002891.1"
                     /translation="MIKTHRVKLNLTRTQFELVREKQMESANCWNYIVNLSKEYYFEH
                     KQWIKKNDIQKLIKGKYNLHSQTIQAISDKFDANRKTISELRKKGNTKAKYPYKTKKF
                     YIIPFKASAINRNAKGNLKLSMSKGRYLELDFNVENIKTAEIVWRNGYYLYYTFDNEL
                     NGVVAKGTNTVGVDLGEIHSIASVTNEGVGLILSNREGRSIKQFRNKMYAYISKRLSK
                     CKKGSRQSKKLWRLKNKIRSKTDNQLMNLYHQTTRKFIDFCVEQKVCEIVLGDIKGVE
                     KDTKKKKRLNRVNRQKISQMEYGRIKDYIKYKAKEQGIEVKLVKENYTSQTCPKCSKK
                     HKPTGRTYSCTCGYETHRDIVGAWNILNKKHKYGLVDFRINHKQPINLKVSTV"
     gene            complement(55399..55911)
                     /locus_tag="KR231_000476"
     CDS             complement(55399..55911)
                     /locus_tag="KR231_000476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HBH0002892.1"
                     /translation="MLEVIKNRRSIRTYIDKNIEEDKITEILKSAMQAPSSKNAQPWE
                     FIIVDDKELLKQLSKSQHRAKHIEFAPLCIVVLGNRDKFLKPGKWIQDLGACTQNLLL
                     EVTNQGLAACWAGVFPKNKVVNKVRQTLDLPLKLVPYALISIGYSEEKNEFIDRFDEN
                     KIHRNVYKNR"
     gene            56361..56837
                     /gene="purE"
                     /locus_tag="KR231_000477"
     CDS             56361..56837
                     /gene="purE"
                     /locus_tag="KR231_000477"
                     /EC_number="4.1.1.21"
                     /EC_number="5.4.99.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide mutase"
                     /protein_id="HBH0002893.1"
                     /translation="MKVAVVMGSKSDYPKLEEGIKLLEKYGIEVVARALSAHRTPEQL
                     SIFLKEIEDDTDVIIAAAGKAAHLPGVIASQTLIPVIGLPIKSSTMDGLDSLLSIVQM
                     PKGIPVATVTIDLGLNAALLALQIMTLKYPKLKEDLKSYREEMAQKVLEDDKNLRG"
     gene            56843..57541
                     /locus_tag="KR231_000478"
     CDS             56843..57541
                     /locus_tag="KR231_000478"
                     /EC_number="6.3.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007285750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazolesuccinocarboxamide
                     synthase"
                     /protein_id="HBH0002894.1"
                     /translation="MLLYEGKAKQVYSTDNENEYVVYYKDDATAFNGEKKAEISSKGI
                     LNNKISTIIFEMLKENNINTHFIKSLSDREMLVKKVEILPLEVIVRNIAAGSICKRVG
                     LEEGVVFDEPIFEISYKNDAYGDPMLNDDYAVAMKLATREELKFLREETLKINELLKA
                     FFLKLNLKLVDFKIEFGKDSEGNIILADEVSPDTCRLWDVNTNEKLDKDRFRKDLGDL
                     VEGYTEVLSRMNNK"
     gene            57553..58920
                     /gene="purF"
                     /locus_tag="KR231_000479"
     CDS             57553..58920
                     /gene="purF"
                     /locus_tag="KR231_000479"
                     /EC_number="2.4.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidophosphoribosyltransferase"
                     /protein_id="HBH0002895.1"
                     /translation="MCGVLGIYSNKDVTKELYYSLYSMQHRGQESCGLALLDDGEIKY
                     KKDMGLVGDVFKENELSKLKGNIGIGHVRYSTAGGSHVSNCQPLVGSCRKRQLAIAHN
                     GNLVNANYLKDMLEEDGYMFQTNSDTEVILYILARYYKGDIVESLKVTMDYIKGAYAL
                     VIMSQEELVAVRDPHGFRPLVLGKKGDEYIFASENCAIDILGGEVIRDVEPGEIIVVK
                     DGELKSYFYSENYKPVKKSCIFEHIYFARNDATIDNVNAYEFRIKCGERLAQNETVKA
                     DMVVPVPDSGWPGAIGYANASGLKISEGLVKNRYVGRTFIKPTQEEREIAVKIKLNPL
                     STIIKGKSIILVDDSIVRGTTSKQLVKSLREAGAKEIHLRITSPPVAYSCYYGIDTPN
                     RSKLIASSNNVEEMREYIGCDSLKFLDIEGMLDATEHKSTFCKACFDGEYPVKKIDKE
                     ELLSC"
     gene            58914..59990
                     /locus_tag="KR231_000480"
     CDS             58914..59990
                     /locus_tag="KR231_000480"
                     /EC_number="6.3.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine cyclo-ligase"
                     /protein_id="HBH0002896.1"
                     /translation="MLTYKESGVDIDEGNRAVDLIKGKIKGTYDGNVVGDLGNFSGLY
                     SLKDFVGMKEPVLLASTDGVGTKLKIAQMMDKHDTVGIDLVAMCVNDLICQGAKPLFF
                     LDYIALGKLVPEHIEKIVGGIADGCKMSGCALIGGETAEMPGMYGEDDYDLAGFSVGI
                     ADKEKIVSGNNVKSGDVLVGISSSGVHSNGFSFIRKIFLETYNYKMEQYVEELGMTVG
                     EALLTPTKIYVKLALDVLAKHDIKAIAHITGGGLIENITRVIPKGLGLDINKKSWEKP
                     PIFKMIEGFNAVDERELHKSFNMGIGLVLIVDKENADDVVNFINNRENDNAAYVDKKY
                     SELLEDKAYIIGEVVDSHEGVELC"
     gene            59984..60577
                     /locus_tag="KR231_000481"
     CDS             59984..60577
                     /locus_tag="KR231_000481"
                     /EC_number="2.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylglycinamide formyltransferase"
                     /protein_id="HBH0002897.1"
                     /translation="MLNIGVLISGGGTNLQAVIDGTESGEIKGQVKVVISSKQGAYGL
                     ERAKNHNIKAICETDEDKIIEILKENKIDLVVLAGYLKIISPKLVNEFRNKMINIHPS
                     LIPSFCGAGFYGEKVHQGVIDYGAKVTGATVHFVDEGADTGPIIMQDVVKVNQDDDAK
                     TLAKRVLEVEHRILKESISLFCENKLKLQGRRVFINE"
     gene            60570..62102
                     /gene="purH"
                     /locus_tag="KR231_000482"
     CDS             60570..62102
                     /gene="purH"
                     /locus_tag="KR231_000482"
                     /EC_number="2.1.2.3"
                     /EC_number="3.5.4.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     phosphoribosylaminoimidazolecarboxamide
                     formyltransferase/IMP cyclohydrolase"
                     /protein_id="HBH0002898.1"
                     /translation="MSKRALISVTDKTGVVEFAKELNKLDYEIISTGNTFKTLKENGV
                     NVMQVEDVTNFPEILDGRVKTLNPYIHGGILYKRDKESHVETVNEHKIHSIDLVAVNL
                     YDFEGTLKAGKSHDEIIENIDIGGPSMIRSAAKNYKDVIVVVDIKDYDSIIEKLKTDT
                     MTLEDRKKLSYKAFSTTGRYDALISSYFAGEVGDTYPDILNLTFQKEQTLRYGENPHQ
                     NGFLYSQSNAKNPILNYEQLGGKELSFNNLNDLHGCLEVMREFKDSEEVVSVAIKHAN
                     SCGVGLGKDAFEAYTKCYEADKVSIFGGIVGITSTIDKATAEKLNEIFLEIVVAYDFE
                     PEALEILKQKKNLRILKLAKIENSLQPYEMKYLDGKLLIQDRNNILAEKSENVTKEKP
                     TDAQLKDMEFGMRVVKNMKSNAIAVVKNGQTLALGCGQTSRIWALKNALENNKDKDFT
                     GAVLASDAFFPFDDCVTLAHEYGISAVVQPGGSIKDKDSIEACDKYDMVMVFTGIRHF
                     KH"
     gene            62113..63363
                     /gene="purD"
                     /locus_tag="KR231_000483"
     CDS             62113..63363
                     /gene="purD"
                     /locus_tag="KR231_000483"
                     /EC_number="6.3.4.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylamine--glycine ligase"
                     /protein_id="HBH0002899.1"
                     /translation="MKILVVGGGGREHAICWKLSKEKNVEKIYCAPGNAGIANVAECV
                     NIGDTNIEELLKFAKENEIGLTIVGPEVPLVMGIVDEFEKEGLRVFGPNKKCAQLEGS
                     KAFSKEFMIKHNIPTAKYKEYTNLEEAISEIDSFGYPVVIKADGLAAGKGVVIPENRE
                     DAIATLKEMMSDKKFGAAGDKIVIEEFLKGIETSILAFVDNDTIVPMASAKDHKKVNN
                     YEQGPNTGGMGTFSPSEIYTEELANKVKETVLEKTLEGFKKDGLNFKGILFVGLMITE
                     DGEKVLEYNVRFGDPETQSVLFRLETDLHEIMEAILDNKLKDIEINYSDDEAVCVMLT
                     SGGYPDSYEKGKIITGLENLDDDIVVFHSGTKMFDGNLVTNGGRVIGITAKSTRVKDA
                     AEKVYENIKKINFEGMHYRTDIGR"
     gene            63388..67194
                     /locus_tag="KR231_000484"
     CDS             63388..67194
                     /locus_tag="KR231_000484"
                     /EC_number="6.3.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase"
                     /protein_id="HBH0002900.1"
                     /translation="MLNTENKDSMVRRVLVEKREGFDLEAKALKKDLVESLHIDNIEN
                     LRILNRYDVEGISEEVYENAAKTIFSEPNLDVVYYEEIPKLNDERVFAIEFLPGQYDQ
                     RGDWAAQCVQIVNQGIRPAINTAKVYILSGKITDEEFSKIKDYCINPVDSREASLEKP
                     ETLKMETEIPTTVEVLDGFIDLDENGLRTFVSEKGLAMTLGDLQHVQKYFKDTEKRNP
                     TITEIKVLDTYWSDHCRHTTFMTEIENVKIEDGKFNDIVKEAYQMYLNSRDNVYVNRH
                     KDICLMDIATVAVKELKKNGKLNDLDESEEINACSINVDVEVDGKMEKYLVMFKNETH
                     NHPTEIEPFGGAATCLGGAIRDPLSGRSYVYQAMRVTGSADPRTTLEDTLPGKLMQRK
                     ITTEAAHGYSSYGNQIGLTTGQVAEVYDENFVAKRMEIGAVIAAAPKENVVRERPEAG
                     DVIVLLGGKTGRDGCGGATGSSKEHSEESILTCSAEVQKGDAPNERKIQRFFRNKEVA
                     QMIKRCNDFGAGGVCVAIGEIADSLDINLDLVPKKYDGLDGTELAISESQERMAVAIK
                     KENKDKFIQLAVEENLEATHVATVTDTGYLRMFWNGKAIVDINREFLDTNGVKQTTDV
                     HVTKVDEENTFFSSNEIVKDVKCASMKDKFTKVLSDLNVCSQKGLVEMFDNTIGGNTV
                     LMPFGGKYQATPTQGMVAKIPVLGGETNTSTIMTYGYNPKVGKWSPFHGALYAVVESV
                     CKLVAIGGNYSTTRLTFQEYFEKLGNNPEKWGKPFSALLGAFYAQSKFEIPAIGGKDS
                     MSGTFKDIEVPPTLVSFAVDTVDAKKVVSPEFKKADSKVVMLCVNKAENDVVDFEELK
                     RNLDKVRELIHGNKVLSTYALGFAGVGEAISKMAFGNKIGFKFSEEAEKAFTDNKLFE
                     ASYGNIVLELANDDLSMLEGYNYVVIGSTVKEASIFIKGEELALDELYKAHCSTLEPI
                     FPTKTEEVKSKIETISYISQGEAKKSSLSIATPRVFIPAFPGTNCEYDSARAFERAGA
                     NASIRVFKNLTYKDIEDSIDTIVNEIKSSQIIMLPGGFSAGDEPDGSGKFIATVFRNP
                     RVQEAINEFLTQKDGLMLGICNGFQVLIKLGLVPYGEIRVPSESAPTLTYNNIGRHQA
                     KIARTRISSNKSPWLAQTNVGDIHNIAISHGEGKFVASEDVMRELIANGQVATQYVDF
                     NNEATYDIEFNPNGSFYAVEGITSADGRVFGKMGHSERIGEEVYKNIIGEKDQKIFES
                     GVKYFR"
     gene            67400..68272
                     /gene="rfbD"
                     /locus_tag="KR231_000485"
     CDS             67400..68272
                     /gene="rfbD"
                     /locus_tag="KR231_000485"
                     /EC_number="1.1.1.133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose reductase"
                     /protein_id="HBH0002901.1"
                     /translation="MKILITGSNGQLGKELVNQLEAINQSINQPKYVILATTRSDLDI
                     SNQTNVDNFILHNKPDVVVNCAAYTKVDACEDNIEIAYKINALGVRNLAIASEKVNAK
                     LIHISTDYVFNGFSKYPYREDNKTEPNSVYGKSKLMGEKFVEQFSHKYFILRTAWLYG
                     NGNNFVKTMIKLSLENKEVNVVNDQFGTPTSTVDLAKIIIRIMETEHYGVYHATCEGE
                     CSWYDFAKKIFKLKNIDIKVNPIKSNEFKCKAPRPLYSVLDNFMLKLIGLNSFRKWEE
                     SIEEYLERYDINEK"
     gene            68381..69250
                     /gene="rfbA"
                     /locus_tag="KR231_000486"
     CDS             68381..69250
                     /gene="rfbA"
                     /locus_tag="KR231_000486"
                     /EC_number="2.7.7.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate thymidylyltransferase RfbA"
                     /protein_id="HBH0002902.1"
                     /translation="MKGIILAGGSGTRLYPITKCISKQTLPIYDKPMIYYPMSVLMLA
                     GIQDILIISTPRDIKAFEELFGDGSSLGLNITYAIQEKANGIAEAFIIGEEFIGNDRV
                     SLVLGDNIFYGYGFSERLENAVKRKGATIFGYHVSNPNSFGVVEFDKDFNVLSIEEKP
                     TVPKSNYAIPGLYFYDNDVVEIAKLVEPSDRGELEITSINSEYLKRGKLKVELLGRGM
                     AWLDTGTHKGLLDASNYVEVVQTRQGLYIACLEEIAYTKGYISREQLMKLAKPLIKTE
                     YGQYLLKLASEDM"
     gene            69299..69856
                     /gene="rfbC"
                     /locus_tag="KR231_000487"
     CDS             69299..69856
                     /gene="rfbC"
                     /locus_tag="KR231_000487"
                     /EC_number="5.1.3.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose 3,5-epimerase"
                     /protein_id="HBH0002903.1"
                     /translation="MGKINVIKTKIEGLYIVEPNVFYDERGYFMESYNKKDFIEQGLD
                     MCFIQDNESSSRKGVLRGMHFQVKYPQGKLVRVTEGEVFDVAVDLRKDSQTFGKWEGV
                     ILSDKNKKQFYIPEGFAHGFLVLSEKAVFSYKCTNYYYPEFENGFIWNDKQISIEWPL
                     KGIEEIFLSEKDKKQKSFKDICTRR"
     gene            69894..70877
                     /gene="rfbB"
                     /locus_tag="KR231_000488"
     CDS             69894..70877
                     /gene="rfbB"
                     /locus_tag="KR231_000488"
                     /EC_number="4.2.1.46"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009904815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-glucose 4,6-dehydratase"
                     /protein_id="HBH0002904.1"
                     /translation="MKKILITGGAGFIGSNFIHYMLNKYVDYFIVNLDLLTYAGNLET
                     LIEIQDNSNYKFVKGDISNREQVYKLFEEERFDIVVNFAAESHVDRSVENPDLFIKTN
                     IIGTQVLLDASIKYGVKRYHQISTDEVYGDLPIDRKDLFFTEQSSINPSSPYSASKAS
                     ADLLVSSYYRTYGLLTTISRCSNNYGPYHFPEKLIPLMILNALENKQLPVYGNGENVR
                     DWLHVYDHCTAIDLIIHKGNIGEIYNIGGHNERSNLEVVKMILNLLGKSEELISYVND
                     RPGHDLRYAIDATKIENELGWKAKYDFDLGIKETVKWYIENESWWKAVLSV"
     gene            70907..71575
                     /locus_tag="KR231_000489"
     CDS             70907..71575
                     /locus_tag="KR231_000489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lytic transglycosylase domain-containing
                     protein"
                     /protein_id="HBH0002905.1"
                     /translation="MNEISSLINILALTQLSGSNTTNQCNCTYNNSSGFDMIMMTLLK
                     ALSQNNQHTSNSYNLLSNSENLFNELDNVVNNTTSRFIDVDTKDKNVKLRIENAVDQA
                     SKKYNVDSNLIKAIIKVESDFNPNTVSSAGAKGLMQLMPENCRDLGVTDPFNIEQNID
                     AGTRHIKEYIDMFGGSIEMGLMAYNGGPGRMKSRGVESISDLYKMPKETQNYIPKVMK
                     YYRG"
     gene            71584..72012
                     /locus_tag="KR231_000490"
     CDS             71584..72012
                     /locus_tag="KR231_000490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YaaR family protein"
                     /protein_id="HBH0002906.1"
                     /translation="MGINIDKLNISPSINMEVKKLKESNKFSDKLNSLKQSSSLEDIK
                     RNLESVKKAGERLVLTQNYGDISIYKNAVKEYLKSVVDNMYSLDKNSSFWEHQYYKNV
                     KIVDSKLEDMTSKLISEEKENIDIVSTVDMIQGLLIDMYR"
     gene            72036..72350
                     /locus_tag="KR231_000491"
     CDS             72036..72350
                     /locus_tag="KR231_000491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FliM/FliN family flagellar motor switch protein"
                     /protein_id="HBH0002907.1"
                     /translation="MNSKKEDIYELNFGQLIEEKSGVIEENQNVFNAKVNVAVSIGNT
                     TETIKNILDLKEGSIIKLSKNVDEKLDIYANDRLFAYGESIITNERLSVRLSKIEDPD
                     VN"
     gene            72502..72777
                     /gene="flgM"
                     /locus_tag="KR231_000492"
     CDS             72502..72777
                     /gene="flgM"
                     /locus_tag="KR231_000492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar biosynthesis anti-sigma factor FlgM"
                     /protein_id="HBH0002908.1"
                     /translation="MDIKNVSSNIVVNNYLKNTSGIKKVEEVKKINKTDKIELSKFAK
                     EMASVSNMSDENIRNKKVDEIKNALENGTYKIKPKEIAKKMIEDMRG"
     gene            72782..73198
                     /locus_tag="KR231_000493"
     CDS             72782..73198
                     /locus_tag="KR231_000493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar protein FlgN"
                     /protein_id="HBH0002909.1"
                     /translation="MITDLKVIIYEEKNIISKMMELLKEQFDYIVEKDLENLNMLNPK
                     LEDISRELASIEIKRRQLFGDDISMSEVVENSNDGYLKEIYTDLKHILALAKNQQESN
                     DSLIKKELIFTKKMINFIKPADKQTTTYNSYGNIRK"
     gene            73216..74526
                     /gene="flgK"
                     /locus_tag="KR231_000494"
     CDS             73216..74526
                     /gene="flgK"
                     /locus_tag="KR231_000494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar hook-associated protein FlgK"
                     /protein_id="HBH0002910.1"
                     /translation="MAGLFSILNTANSGMNAHQKAIQTISHNISNLDTDGYSRQRTEF
                     ATNSPMYMPSLSNSIARGQLGTGVHVTDVTRARNSFYDYQFRAEAHKYGKTVSKYDYY
                     NTIETILNEPSDYGISAGIDDFFKGWESLSKDINSDSKKSLVVENASNLATLISESYK
                     KLDKLKEDIDSNIDTEIKQINDMLKSLEDLNKSIDIISGSGSTPNDLLDERDRILDNL
                     SFKLDFENSDVKNMLADGKLELNELKNPDGTWKTGISGTLQGLFEMHGKIDTYKSDLK
                     DVSDGLAKQINDVYNTSAGITVTDFFITSNVDGEDIIKINPAIKSNPNELKLTADEAS
                     KIAKLKDEKIDIGVAGGKVSTISDHYKAFAESIGLDSQKVNQDEANQRKIINNIDNSR
                     MSVSGVSLDEEMTELIKIQRSYQASAKVMSTAVQLLDVVINGII"
     gene            74545..75477
                     /gene="flgL"
                     /locus_tag="KR231_000495"
     CDS             74545..75477
                     /gene="flgL"
                     /locus_tag="KR231_000495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar hook-associated protein FlgL"
                     /protein_id="HBH0002911.1"
                     /translation="MRVSTGMMSSSYLNSLQDNLQRLDKVNRQVNTTKEINKLSDNPY
                     KAIKILNSKSEIKTMETYVENCKDTGNWLETTDTALDQLGKLLSDIKKTLVASGDGAY
                     SDDELKTLSNETNEKMKEIANALNATHEGKYIFSGSNTGVPPVECIDNADGSVSLKFN
                     SSLNLNKLNDSLSMDIAQGISVDYNVKLSSLGFDPTKTDPFEELNNISKKLANPDADA
                     IKELTTTCLGDMEQLIENTVNVRSIYGTKANTVEAMKEKNDDSLIQLKDILSQNEEID
                     YGEKLVQLKAAELTYQASLQTGGKLFNVSILDYI"
     gene            75493..75885
                     /locus_tag="KR231_000496"
     CDS             75493..75885
                     /locus_tag="KR231_000496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420991.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar assembly protein FliW"
                     /protein_id="HBH0002912.1"
                     /translation="MMKVTLKKGILGFENLKEYELLDIEDNDYLKEFNSTEEEGIGFV
                     VVSPFEIINEYEIVLNQETIEKLEVKSPKDVVLFNIITLGQTFEESTVNMKAPIVINI
                     KTNFGMQIILQDDKYSIRHPLLRGDSGC"
     gene            75879..76091
                     /gene="csrA"
                     /locus_tag="KR231_000497"
     CDS             75879..76091
                     /gene="csrA"
                     /locus_tag="KR231_000497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011987028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbon storage regulator CsrA"
                     /protein_id="HBH0002913.1"
                     /translation="MLVISRKKDEAVLIGESIEVKIVGVDGNNVKLAISAPNNISILR
                     KEIYEKVKSENIKATNKNIKILKSLK"
     gene            76113..76508
                     /gene="fliS"
                     /locus_tag="KR231_000498"
     CDS             76113..76508
                     /gene="fliS"
                     /locus_tag="KR231_000498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar export chaperone FliS"
                     /protein_id="HBH0002914.1"
                     /translation="MYGENPYNSYKQNAVFMASKEQLLLMLVDGAVKYTKIAKTAILD
                     KNTQKAHRELIRVQDIFTELMVTLDQNAGQWAKDMYRVYDFVRYELSRANIRKDIQII
                     DNVLPVIEQIKDTWHEADKKSKEERSRYK"
     gene            76508..76864
                     /gene="fliS"
                     /locus_tag="KR231_000499"
     CDS             76508..76864
                     /gene="fliS"
                     /locus_tag="KR231_000499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar export chaperone FliS"
                     /protein_id="HBH0002915.1"
                     /translation="MELNLAELDKLSKEELLLMLVDGTVKYTNISKEALLNNDYLKAH
                     NELVRVQNIFTELMTTLDQDAGQWAKDMYKVYEFIKSELAIADENKDIKIIDDILPIV
                     KQIRDTWHEVYNQLKI"
     gene            76885..78408
                     /gene="fliD"
                     /locus_tag="KR231_000500"
     CDS             76885..78408
                     /gene="fliD"
                     /locus_tag="KR231_000500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar filament capping protein FliD"
                     /protein_id="HBH0002916.1"
                     /translation="MSSISPIRVTGLSGNFDMEGIIEASMIRDKEKVDKAKQEQQIVK
                     WKQEIYRNVIQESKDLYDKYLSVNSPNSIVSEKAYSSTRITSSDESIIVAKGSAGAEK
                     INYQFAVSQMAEPAKFTIKLNSSEPIVQQFPPNASGASSLTIGDVNIPISEQDTTSTI
                     VSKINSLCADNDIKASYSEMTGELIISRKQTGSSSDINLRVIGNDNLAQQIANDNGIT
                     FINDAGGNKVANVYGKNLEADVTDEHGRVTHISKEQNSFNIDNIDYNVNSKGTAKLTS
                     VTDTEEAVKNMQAFVDDYNKLMDKVYGLVTTKKPKDYPPLTDAQKEDMTTEEIEKWEK
                     KAKEGILRNDDELRGFVEDIQSAFFGDGKNIIALRKLGINESENYNKKGQISFNADTF
                     SKALIDDSDKVYKTLAGYSSNYDDKGMFEKLKDIVYEYSGSSTSKLPKKAGIEKTASA
                     SENVYSKQIAEQERNISRLVEKMNDKEKRLYAKYSALESLLNQYSSQMNYFSQAQGN"
     gene            78411..78746
                     /gene="fliT"
                     /locus_tag="KR231_000501"
     CDS             78411..78746
                     /gene="fliT"
                     /locus_tag="KR231_000501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar protein FliT"
                     /protein_id="HBH0002917.1"
                     /translation="MDKLKEKLNLYKDISLQIINLIEKEEYIKISIKLGERQEIINSV
                     SEIDRNDFIQLYNRMELIEIDSRIRDILQGQLLEVKKELHEYKLTKQVNTMYYNLNRE
                     KVNIFNKKV"
     gene            78848..79720
                     /locus_tag="KR231_000502"
     CDS             78848..79720
                     /locus_tag="KR231_000502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellin"
                     /protein_id="HBH0002918.1"
                     /translation="MRVNTNVSALIANNQMGRNVNAQSKSMEKLSSGVRIKRAADDAA
                     GLAISEKMRAQIKGLDQAGRNVQDGISVVQTAEGALEETGNILQRMRTLSVQSSNETN
                     TAEERQKIADELLQLKDEVERISSSIEFNGKKLLDGSSTEIRLQVGANFGTNVAGTSN
                     NNNEIKVALVNTSSIMSKAGITSSTIASLNADGTSGTNAAKQMVSSLDVALKELNTSR
                     AKLGAQQNRLESTQNNLNNTIENVTAAESRIRDTDVASEMVNLSKMNILVQASQSMLA
                     QANQQPQGVLQLLG"
     gene            79813..>81898
                     /locus_tag="KR231_000503"
     CDS             79813..>81898
                     /locus_tag="KR231_000503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HBH0002919.1"
                     /translation="MLLSIVMIVKNEEKILEKTLKSLTTLRNSIESELIIVDTGSTDD
                     TIKISKKYTEKVYFHNWNNDFSSMRNISISYAKGEWLLILDADEILIDSSTIVKFFKD
                     GLDKKFNSASIQLKNLYSYDKKLYGYCSVLRLFKNVDFRYHGKVHEQPIYKNPIFNNV
                     ADFEHYGYLFEDEEIRLNKVKRNEKLLFQELKENDNSPYTNYQLGKNFIILGKYQEAL
                     YYLEKSYELYSKLELAPGYLITSLVKTYLYLGKHKKCERLCLKYIKKDMNNIDIYYYI
                     AQAQVDLGKYENSIDSYKRYIYLLDNYEISTQANSLFSDTDTVGLRDEAIITLIKIYY
                     KLEKYEFVISEYNNIEDVEKKKNVYFSLFMSLYKLNRFEDIKNYYKEVSNSKIEKNSF
                     YRNIEEVINNIKEDEKEYVYKILCDIEGNYGILNQIRINKCVSIDKCKEILNEEKEII
                     YAYIIKIAFEEKIDLLDIFYEMEYVWIEKYLKYLLALERSFNLVLYKYIISRPNTSDM
                     EKIRVYKAISKVVLESISLSDEKYKEIFYLYIMYSYKYIRYIYSNLSDFELIKFVCND
                     LDKFTIEFKHLLDIKNKVNNANEKLEYIHSMRKLLNEYPFYNKIIKILIGELEENIKE
                     SEEFKDLKDSFIISIENMIETGKINDAKLLVDDYSKTFVDDIKILNIKGILYMFENKL
                     DKADFMLKKALSL"
BASE COUNT        32165 a         8997 c        14289 g        26447 t
ORIGIN      
        1 tttaactaga ttagattgta tttcctttga atcaatttgt aataaattta ttatttctat
       61 aaatgtagag atatctatat atctgtgacc taaatcaaat atatctgaga taaagctagg
      121 tactttttct ggaactcctg gagttatagc tatttttata tttttatagt tattatcatt
      181 catatatgga attggtctaa tattagtcac tccaatttta taaaataaac ttatagtttc
      241 tagagtagtt tcatcagaat catttacgat tagaacattt gtaccctgtg gtaaagatag
      301 tagattataa attttatctt ccctaaaagt tcttcttacc acaatcactt ttttcttatc
      361 tagtatatta tttataattt tgtctaatct ttctactgac attactaata tcacatcatc
      421 atttataata tcattatcat ttatttcatt tatgaagtat ctattaatat ttatagaatc
      481 tccaaaaact aatttcaaat tattttctaa aaagtctatt aaatcttttc tactatcatt
      541 taccagagct actgattttt tcatttattt ctccttatat aataaatagt ttccaacaaa
      601 atagttgtat aaagcaatct aattttgata atttaaattt atcaaataaa aaagaaagtg
      661 tctataatga ctttctaaaa gttgcattaa gacactttct ttcttatagt taaaaatctt
      721 gtcaccaaat ccccctaatt gttgcttaaa acttaaactg tatgtatatt tttcatttct
      781 attcgattaa attataatat acacccaaaa aaatttattt taataaattc tattgataat
      841 ataattttat aaatatagaa ttatattaaa ataaattata tatgaaaata tatatgtata
      901 agtttattct gcgtgagtag aatggatttg tcaagtttaa tttagttgta attctatctt
      961 ttattaaaaa taacataaat taaaacatat aaataaaata ttttatacaa tatattgtaa
     1021 aggaggtaac tttgatgaaa gcagaaaaaa caagtatata tccaattatt aaaaataatt
     1081 taaacaaaat atcaattgtt gaatataaaa agggtcaaag atttgtagca tcagataaag
     1141 acttacaaga agtgttcttt ataatagagg gagttgcatt agtggagtgt actactagag
     1201 gaggaaataa atttcttgtt gacattgtac ctgaaaatga atttataggc aaaattagtt
     1261 acatatatga acataatttg aaatgtgata tatttgcaaa gactaatata aaattatttc
     1321 gatttgaaaa aaatgtattt gaagagtttt atctcaaacc agattttatt gcactatttc
     1381 acagaaaatg tacaagaaga atatatgaat tatataaaac cagaatggta agagaactat
     1441 tttcttgcac agaagttatt gcctattgta tatcaaataa acaagaaaat aatgtctgca
     1501 atataaaagc tattcgtaat ttcagtgaaa tctattcaat tagtagaaaa agtagatacc
     1561 attctctgct aaagttaact gaaaaggaga tagtaaaaaa aatgggtaat acatatgaaa
     1621 ttttaaacta tgatgaatta cataaattgg catttgaagt aaaagaattt ttggaagatg
     1681 agtaaaaatt gttacttaat caaaataaag tataataatt tctgtaaaaa atagaaatag
     1741 tctcactgaa aatcaaaaat actttagtta ttttcaatga gactgtttag aaatattgta
     1801 tacttataat gtatagtata attattaatc aatttccttt actatattaa tagcccattt
     1861 tttagataat gctctaggaa caccaaatat aaacttaacc acttcttcac tataagtgag
     1921 caaaacgagt acaaatatag gtgcaccttt aaatgcagct ataaaagtta gaggaataga
     1981 agctaaccac atacatccta attctaaaaa tagagcatat ttagtatctc ctccacttct
     2041 taaaatacca attataacca atgtattaaa agatttaaga gccattagta ttcccattat
     2101 aaagaatatc ttagttatat cagaagctaa gctatcagaa acactaaaca tttttaataa
     2161 taatggtata tttaaaatta aaataattcc aagtattaaa ccagctgaaa atacaagtat
     2221 agaaaacttt ttagcatatt caatggctct tttaatatgg tcagctccaa gttcatttcc
     2281 aagcataata gatgcaccag atgcaataca tacagctgtc attatgaaga aattacctgt
     2341 actggttgct atctggctag ctgctatagc agaagtacca gctcttgcat atgcaacaga
     2401 atacaggaca gttccaattg cccatacaga gtcatttaca aatataggaa agctttttga
     2461 tgaaaaagat tttataaaaa ttttatcaat agcttttaga ttttttagac caaactttaa
     2521 tatatagtct tttttataaa ggtaaacata agtaatcatt aaaattaatt cacatattct
     2581 agcaataaca gtagctagag cagcaccttt tacacccaat gcaggaagac cgaagttacc
     2641 aaatataaat ccataattta aaataacatt tgttacaagt gcaaatgcac tacaaatcat
     2701 acctaactta ggatttctaa cacctcttga accagtacta aatacagtac ttacagcaat
     2761 taatggataa ctaaatactg caatactaaa gtaatctata caaagtttta ccacctcaga
     2821 atcatacgaa aatatgtgta taattggctt tggtgttagt aaagcaggaa taacaaatac
     2881 aaaacttaaa acaattgcca atacacaagt aagacctgtg acttttctta tattactcac
     2941 atccttcttt ccataaaact gtgaaataaa aactccagca cctcctgtga taccagataa
     3001 ggacatatta aaaagaaaga aaaattggtt tgcaactcca actgaagcta cagatgtttc
     3061 ccccaaacta cttatcataa ttgtatctat tacatttaca gaagtagaaa ttaagttctg
     3121 tatgataata ggtatacata aagatagaag tattttataa aatcttttat tttcgtcttt
     3181 taaagaaaat agttcttgca aataatcctc tcctttttac ataaattctt cccactcatc
     3241 atatagagag gcaaggttat tttctaaatt aattttttct tggctaactt ctttagcttt
     3301 atctggatta gagtatactt cttcttgaca taaaagtata tctaattttt caatttcaat
     3361 ctctaacttt tcaatttctt tttctatatt ttgtcttttt attctatttt tcttttctat
     3421 ttctctttgt tctctctctt ttcttttttc atcttttatt tgagttctag ttttttcttc
     3481 tttttcttct ataatactca tctcttggat ttgccttttt ttatctatat aataatcata
     3541 atttcccaga tattcagtaa ttccattttc atctaaaact aaaattttat caacaacagt
     3601 atttagaaag tatctatcat gtgatattgt aaatatagtc ccatcataat tagttaaggc
     3661 ctcttcaagg acttccttag aatcaatatc taggtgatta gtaggctcat ctaataacaa
     3721 taagtttgca tttgatagta taagtttaag tatggcaact ctagctcttt ctccaccact
     3781 caatgtagaa atcttcttaa aaacttcttc atctacaaat aaaaatgccc ctaacatatt
     3841 tctcaaagta gtttgagtaa gatgagtatt attttcccaa atctcatcaa ttattgtgtt
     3901 atctaaatta agagtttttt gttcctgatg gaagtaggaa acatgtacat tagttccaaa
     3961 tttaatattg ccactaagag gttgtagttc attagttatt attttaaata atgtagattt
     4021 gccaacacca tttgcaccta taagtgcaac tttttcccct ctatatatat ctaaatccaa
     4081 gtctttaaaa agtattcttt ctccataacc catagataca tctctaattt gaagaacatc
     4141 attaccactc tggacagaag gcgtaaattg tatacgagct tttttcctat aagcttctgg
     4201 tttatctaaa acatctactt tgtctaatgc tttttcttta cttcttgcac gctttaggtg
     4261 tttttctcta ccataagctt ttagtctttc aattgattct tcttgctttt ttatttcttt
     4321 ttgttggtct tcaaatttct taagctctag ttctttttct attttagata actcaacaaa
     4381 tttagagtag ttaccattat atactttaag ctttttattg tgaacttcaa aaattctatt
     4441 tacggattgg tctaagaaat atctatcatg agatattaac atgacagtcc ctttatattg
     4501 ttttaaaaat acttctaacc attctattgc ttcagagtct aagtggttag taggttcatc
     4561 aagtaacaat agagttggtt tcttaagaag taattttcct aaaagaactc tagttttttc
     4621 accaccagaa agtatgctta ttggcttatc catatcattg tcactaaatc ctaatccctt
     4681 tagaactcct ttggcttcag atttatatcc atatccattt aaatctgaaa ataattctag
     4741 tttatgtgaa tattcatcca tgattttttc tataattgga gagtttgttt ttgtactttc
     4801 ttcagatatt ttaacctcca attctcttaa ataggattcc atttctatca aatttttaaa
     4861 aacttctagt acttcttcca aaatagtatt atccgaataa aaattggtat tttgttctaa
     4921 atatccgatt tcacaatctt tagaagtgta aatatctcca ctatcatatc cataaattcc
     4981 tgaaattatt ttaaataaag tagtttttcc agtaccatta acaccgatta taccaatttt
     5041 atcgccttca tttactgtaa aactaatatt ttctaatata gaatctatac caaaactttt
     5101 atttaagtta ttacatgaca aaacaatcat aaatttctac ctccttgaac tatctaaaat
     5161 tataatgttt tgatataata taatcaaggt tatatgtatt agttttgaaa aagaaatatt
     5221 ttattgtgaa tcaaacaaaa aagaggacac ttttaggagg tgaagatgtt gggaaataaa
     5281 aatatatcaa tggcagttat aagaaggctc ccaaaatatc atagatatct tggagactta
     5341 ttagataggg atatacaaag aatatcttct aaagaattga gtgatataat agggtttacc
     5401 gcttctcaaa taagacaaga tttaaacaac tttggtggat ttggacaaca aggatatggt
     5461 tataatgtag aagctcttca tactgagata ggtaaaattc ttgggttgga tcgaccatac
     5521 aacgcagttc ttgtaggagc aggtaactta ggacaagcta tagccaatta tgcaggattt
     5581 agaaaagctg gattcgagat aaaagcttta tttgatgcaa atcctagaat gataggttta
     5641 aagataagag agtttgaagt attagattca gatactttag aagactttat aaaaaacaat
     5701 aatatagata ttgctgtatt atgtatacct aaaaatggag cacaagaagt tattaataga
     5761 gttgtaaaag ctggaatcaa aggtgtatgg aattttgcac ctttagattt agaagttccg
     5821 aaaggtgtta tagttgaaaa tgtaaactta acagaaagtt tatttacctt atcgtattta
     5881 atgaaagaag gaaagtagac aacttaaaca tattaataat gagcagttgt aaagagtatt
     5941 gagaaagtca gaagatttaa tattaaatcc tctggctttt tgaaatatta ggataaaaat
     6001 ttaaataatg tatggaaata aacaatatta aggagagtgg tttttgtgga ggaattatgg
     6061 aaaaaggcaa ttgaatttca tggtcatgaa tgtccagggt tagctatagg atttaaagca
     6121 gcacttgcag caaaaaaata tttaggatgt aaacagtcag gagatgagga aattgtatgt
     6181 atttctgaaa atgatgcttg tggaatagat ggtatacaag tagtgctaag ttgcacaatg
     6241 ggtaagggaa atttactact taggatgact ggaaaatcag tatatcattt ctttaataga
     6301 gaaaatggaa aatctataag gatatatgta aagtcaaaac catttgagat ggatagagaa
     6361 ggatacaaaa gatatttatt agaaagtgat tttgaagaaa tatttgagat tacagatact
     6421 aagttaagac ttcctgaaaa agcaagaata tttaaatccc ttaaatgtga agtgtgtggt
     6481 gaatttgcat ctgagcaata tataaggatt gaagaaggaa agaaagtatg tcttgattgt
     6541 tttgataaat atgaaagatt ttatgaagag tattaaaatt ataaattaga ttaaagttaa
     6601 aagtattaga tatgtgctaa cagtatttta agatgaatta ggtagcaaca taataaagta
     6661 tataaataat attaattgaa tcatacataa ttaaaaagag gctgattagt atttataaaa
     6721 taaaatcagt ctctttatga ataacgaatt attattctgg ttgaggtgca tctacaggac
     6781 aagctcctgc acaagaacca cagtctatac aagaaccagc atctataaca tatgcgtcgt
     6841 ctccagctga tatacagcta acagggcatt cagcctcaca agcaccacag cttatacaag
     6901 cgtcagtaat tttatatgcc attttgaaat cctccctttt atatgtattg taattcaata
     6961 acattataac aaatattatt gaatataaca attaaattaa ttctacaaca aaaactttat
     7021 tatgatattc ttgttttaaa gttttacaat aaagtttaat ctgcttatat ttttatttat
     7081 tttaaagaag tttattttaa aaataaaatt aaatttaaaa agttatgtat tgattatatt
     7141 taaaaatgtt atactctaaa aaagtatatt ttatttaaaa atttattaat acaaaggaga
     7201 tttactatga aaaataaatt agtttacata tgtattatga gtctattgct atttgtagta
     7261 ggatgttcta ataatccaaa taaggaaagt accattaaaa aagactctaa gaataaccaa
     7321 agccaagtta aagaagaaaa aagagaacct gtgaaaaaag atataactat aagtttcgct
     7381 ggtgatgtaa ctatggggaa ctataaaggt tcatcatatt atggcagttt tgaccatgaa
     7441 tttaaaagac aaggagaaga ttacaattat tttcttaaaa atgtaaaacc tgtatttgaa
     7501 aaagatgact taacagtggt taatttagaa ggtccactta ctacagcgtc aaatgcaaaa
     7561 gaaaaaaaat ttgcatttaa aggaaagcct ggatatgtaa atattttaaa atctggaagt
     7621 gtagaggcag taagtattgc aaataatcat tcagaagatt attttgaaga aggaatgaaa
     7681 gatacacagt ttatattgga cgagaataaa ataaattatt ttggattagg gaaagatgct
     7741 gttgtagatg tcaaaggaat taaagtgggt ctattagggt ataatggatt atcaactgaa
     7801 tataatgaaa aaaatttaaa acaaatggaa gatgatatta agtccttaaa aaagaaatcg
     7861 gatgttgttg tagtgtactt tcattggggg atagaattag attattatcc agataaaaaa
     7921 caaaaagatt ttgctcatta tgctatagac aagggagcag atttagttat ggggtctcac
     7981 ccacatgtga ttcaaggaat agaaaagtat aaaaataagt atatagctta tagtctaggg
     8041 aatttttgct ttggaggaaa taagaatcct tctgatacag atagttatat atatcaacaa
     8101 acctttactt tttcagataa taaattaact tcaattaaag agccaaatat aataccaact
     8161 tcaataacat ctagtaactc cagaaataat tatcaaccaa aaatattgga tggaagtgag
     8221 aaggatagag ttttaaataa acttgaaaaa ataagcaaag atttaaataa ataaaatgta
     8281 aaaaaaaata aatatatata tttattttaa taatttatat tttgtttagg gtatggtaaa
     8341 tcgtggtatt aaataagtag attttaatag ttaaattata gtcaattata ataaagctat
     8401 ttaatctact tttttaatat aaaaatataa gggggaattt gtaatggctt gtaacacttg
     8461 taaaatgtgc gaaagtgcag acaagaaatt agaaagtttt gtagcttcaa aggatgttga
     8521 aacagcattt catagaacag aagatcagaa agttaagtgt ggttttggac ttcagggggt
     8581 ttgttgtaga ctctgttcaa atggaccatg tagagtaact cctaaatcac caagaggtat
     8641 atgtggagca gatgcagaca ctatagtagc aagaaacttt ttaagagcag tagcatcagg
     8701 agcagcttgt tatttacatg tggtagaaaa tacagctaag aatttaaaaa atgttggaat
     8761 aactaaaggt gttgttaaag gagaaaaaac attaaatcaa ttagcagaga tgtttggaat
     8821 agaaagtgat gaaaagtatg ataaatgtat aaaggttgca gacaaagtta tcaacgattt
     8881 gtataaatca agagatgata aaatggaatt agtagaaaaa atagcttatg cacctagagt
     8941 gaaaaagtgg aaagagttag gtataatgcc tggtggtgca aagtcagaag tttttgatgc
     9001 aatagtaaaa tcatcaacaa atttaaacag tgacccagta gacatgctag ttaattgttt
     9061 gaacttaggt atatcaacag gattatatgg tcttacacta actaatcttt taaatgatgt
     9121 tatgttggga gaaccagtta taagaatggc tcctgtagga tttaatgtaa tagacccaga
     9181 ctacataaat ataatgataa caggtcatca acattcaaca tttgcaaatt tccaagatag
     9241 attaaaagat gaagatgtta taaaattagc tcaatctgtt ggcgcaaaag gatttaagtt
     9301 agtaggatgt acatgtgttg gtcaagattt acaattaaga ggagaacatt atcaagaagt
     9361 atttgctgga catgcaggta acaattttac aagtgaggct gttttatcaa ctggagcaat
     9421 agatatagtt ctttcagaat ttaactgtac tataccaggg cttgaaccaa tagcagataa
     9481 atataaagta aaaatggttt gtttagatga tgttgctaaa aaagcgaatg cagaatgcat
     9541 aggtttagac agaagtaaat tagatgaact tagtaacact ttaatagaaa aagcattgga
     9601 gtcttataag gagagaagag gaagtattga aatagatata ccaaaagacc atggatttga
     9661 acaatctttg actggtgtaa gtgaaaagaa cttgaaagcg tttttaggag attcatggaa
     9721 acctcttatt aatttaattg cagaaggaaa aattaaaggt gttgcagctg ttgtaggatg
     9781 ttcaaatatg acagcaggag gacatgatgt aaatactgtt gaacttacta aagaattgat
     9841 taaaaaagat ataatagtac tatctgcagg atgttctact ggaggattag aaaatgttgg
     9901 tcttatgtca cctggagcag aagaattggc aggagaaaac ttaaaagaag tatgtaagac
     9961 tttaggaata ccaccagtat taaactttgg accatgtcta gctataggaa gactagaaat
    10021 agtagcaaca gaattagcag ctgaacttgg aattgaccta ccacaattac cattagtgct
    10081 ttcagctcca caatggttgg aagaacaagc attagctgat ggagcttttg gtcttgccct
    10141 tggcttacct cttcatttag ctttacctcc atttataaca ggaggaaaat tggtaacaga
    10201 agtattaaca gaaaaattaa aagacttaac aggaggacat gttatagtga atccagaccc
    10261 taaatcttca gctaatcaat tagaagaaat aataatagat agaagaaaaa atttagggtt
    10321 aaaggatgtg gaatgcaatg catagaattt ttataaataa agatttatgt acaggatgta
    10381 agagctgtgt actagcatgt atgctaaaac acaataaaga ttatgacatg tacactcttg
    10441 atttagaaaa tatagataat gatagtagag ggcatataga attagatagt agacataata
    10501 atccagttcc aattctttgt agacactgtg atgaacctga atgtgtatta gcatgtatga
    10561 gtggtgcaat gcataaagat agtgaaagtg gaatcgtttc atatgatgaa gagaaatgtg
    10621 gttcatgtta tatgtgtgta atgtcttgtc catatggatt attaaagcca gatgatagaa
    10681 gcaagcagaa catacttaaa tgtgatttat gtaaagatga ggagtatcct agatgtgtag
    10741 ctaattgccc aagtggagca attgaattac agaaggagga aaatgatgaa ttatgtagtg
    10801 ttaggggcta gtgcagctgg tataaatgca gtaaaaacat taagagaatt agataaagat
    10861 tcaaatatag tagtaatttc taaagatgaa aacgtatatt caagatgtat gttgcatcac
    10921 gttatatctg aacacagaac tttaaaacaa ataaattttg ttgatgaaga ttttatggag
    10981 caaaataatg taaaatggat tgcaggtaag actgttaaag gtatagacat aaataaaaag
    11041 gtagttcaga cagaagacat tactgtaaat tatgataaac ttttaatagc tacaggtgca
    11101 tcttctgcta ttcctcctat aaaaaattta agagatggaa attttgtata ttctgtgaga
    11161 aacatagatg atatttataa aataaaagaa aaagcacaaa attctaaaaa tgtagttata
    11221 ataggtgctg gtttagttgg tatagatgca ttagtgggat tatttaaata tgagcagtta
    11281 aatatttctg tagcttttat ggaaaagtac attttagata gacaattgga tgaatataca
    11341 gcatcagtgt atgaaaataa gttcaaagaa aaaggtgtaa aattttaccc aagtgcatca
    11401 atacaagaaa ttgtattgga taacagtaaa aatgttacag gtgttgcatt ttcaaatggt
    11461 gaagttttag atgcagacat ggtaattgta gctacagggg ttaaaccaaa tgctgacttt
    11521 ttagatggaa caggaataga atatgataga ggtataataa tagatgatat gtgccaaaca
    11581 acacaaaaag acatatatgc agcaggagat gttgtaggta aaaatgctat ttggcctctg
    11641 gcagtaaagc aaggaattgt agctgcctat aatatggttg gaaaagataa gaagatagaa
    11701 gatgaatttg cttttaaaaa tagtatgaat ttcatggata taccaactat ttctatagga
    11761 atgaatacac ctgtagatga tagctataaa gtattaacca gacatggaat taatgattat
    11821 aaaaagtttg tttttaaaga taatgtaatc tatggagcag ttatacaagg agatatttca
    11881 tatgtaggtg tattaactta tttaataaaa aataaagttg aaatatatga tttagaaaat
    11941 aggatatttg atatatgtta tgcagacttt tttaatataa aagaaaatgg agaattttgt
    12001 tatagtgtat agtatatacg tggagtaagg tttataaata cagtaaatca ataaatagag
    12061 ttattctaaa ataagaaaaa tgacaaatct tatttagaaa tagctctatt ttttgtaatt
    12121 aaatttaaat tatattcaat ttgtaaaata ttattttgaa caattataca tatactctct
    12181 agttagaggt aaatcatttt ttataccttt agtgaaaagt atttgatgta tatctataat
    12241 accagtgttg aaagcagcag cacaagaaca aaggtataaa tcccacattc ttataaactt
    12301 atcatcaaac atttctttaa tctttggaag attctcagag aaattttttt gccagtatag
    12361 taaggttttt acataatgta atcttaaact ttctacgtct atagtatgat atttgtaatc
    12421 actacaaata tgtatcattt ctcttaggct aggaataact cctcctggga aaatatattt
    12481 ttttatccaa gggtctccat aagattcctg caatccactt atatagtgaa gtaaaaacaa
    12541 tccaccatct tttaaaacag catttacgtt tttaatgaaa agttcatagt tttctctacc
    12601 aacatgttca agcatcccaa cgcttacaac tctatcaaac ataaggtctg atttttttaa
    12661 ttctctatag tccataagtc ttacctcaag atagtcttga aggttctctt ctttaattct
    12721 tgcgttaaat tccttaaatt gctcttcgct aagtgtaatt ccaacgccgt gaattttata
    12781 tttttttgca gcttctatta gtaaaaatcc ccaaccacaa ccaatatcga gaaggctcat
    12841 accttcctct aaatttagtt tagttaatat gtggtgaact ttattgactt gagcatcata
    12901 aagagtatca ttatcatttc taaagtatgc acaagaataa ctaagtgtct tatctaacca
    12961 taagctataa aaatcgttgc caatgtcata gtgggcatgt atttctttct tttgatgtct
    13021 cattgaattt gatgagtgca atagatgttt tacagctgaa ttatcaatat tgaatttgtc
    13081 tatttgtttt aaaagtagat ttaaagttaa gaataaatct ccctcaactt caatgtctct
    13141 atttatgtag gcttctccaa gtgctaaaga tgtacttttt aatagttcag acttgctaat
    13201 atcattattt actataactt tgaactgagg ggagccctct ccaattagaa attcttcctc
    13261 atctttaagc ctaactagaa atggtgtttc accaaatttc tctaaatagt cttttaaaaa
    13321 attttttgta atattcatat taccagctcc ttctaatgta aatccagtaa gtttccctgc
    13381 ttaaaatata ttatagtcct ttttttaaaa aagtaaaatt ttttcaataa attttttatt
    13441 taaaggaaat ttattttttg taaagaaatt tcatgttgta gtatattttt tgcttataaa
    13501 ttttggtact ggatataata ttaaactgtt aatgatataa taaatttaat ctataaagta
    13561 aataaaattt tgtaataaat agttaaagct attttataag gagatatatg atggaagtat
    13621 atgctttggt tgggtcaagt ggcacaggga agagctttaa ggctttagag ttcgcatatg
    13681 aaaatgatat agaatatata attgatgatg ggattttaat atacaaaaac aaggttttag
    13741 ctgggatatc ggcaaaacaa gcaaatacta ctatagaagc agttaaaagg gctatttttt
    13801 ataatctgga gcatagacaa gaagttagag aagcaattaa aaaagaaaat ataagaaaaa
    13861 ttcttattat tgggacatca aaaaaaatgg ttaatcaaat tgtagagaga ttgtcaattg
    13921 gaagggtttg caagtttata aatatacaag atataagtac taaatatgaa atagaaatag
    13981 caaaacaagc tagaaaagaa ggaaatcatg taattcctgt tccagcagtt gagataaaaa
    14041 gtatggcaag tggtcttagt ataaattctt tgaagagact ttttagaaaa ggaaataata
    14101 ggaatatggt agttttagaa aaaacaatta taagaccaac ttttagttat ataggaaagt
    14161 tttatattag tgctgatgta attaaacaga ttattgaata tgaagtatac aactttggaa
    14221 gcattgatag aataaataaa atcaatatag agaattgcaa taattttatg aatatttttg
    14281 taagtataaa tatcaatgat ttagaaacta taaaaaaaat tgaagacata caacagacaa
    14341 taaaaaagtc tattgagaaa atgactttag ttaatgtaca aaaaatagat attaacattc
    14401 ataaaattaa aaaaataaac ttcctccaat gttaaaaaat aaactgagaa aatgatatac
    14461 taatttgcaa taaagtgtgc tataattaaa ctgtaaattt aggaaatggt tttttctaaa
    14521 tggagtatac ataattataa cgtatttata agggggcttt caaatgtcag gaaaagatgt
    14581 aaatgtcttc gagatggcgc aatctcaagt aaaaaatgca tgtgataaat taggtatgga
    14641 accagcagtt tatgaattat taaaagaacc tatgagagtt atagaggttt caattccagt
    14701 aaaaatggat gatggttcta taaaaacttt taaaggattt agatcacaac ataatgatgc
    14761 agtagggcca acaaaaggtg gaataagatt ccatcaaaat gtttcaagag acgaagtaaa
    14821 agctttatct atatggatga ctttcaagtg ttctgtaaca ggtataccat atggtggagg
    14881 taaaggtgga ataatagtag atccatcaac tttatctcaa ggtgaattag aaagattaag
    14941 tagaggatac atagatggaa tatataaatt aataggtgag aaagttgacg ttcctgcacc
    15001 agacgtaaat actaatggtc aaataatgtc ttggatggtt gatgagtaca ataaattaac
    15061 tggacaaagt tctataggtg ttataactgg taagccagtt gaatttggtg gttctttagg
    15121 aagaacagct gctactggat ttggtgttgc tgttactgca agagaagctg ctgctaaatt
    15181 aggaatagat atgaaaaaag ctaaaatagc tgttcaaggt ataggaaacg ttggttctta
    15241 tacagttctt aactgtgaaa aacttggtgg tactgttgta gctatggctg aatggtgtaa
    15301 atcagaaggt tcttatgcta tatacaatga aaatggttta gatggtcaag ctatgttaga
    15361 ttatatgaaa gaacatggta acttattaaa cttcccagga gctaagagaa tatctttaga
    15421 agagttctgg gcttcagatg ttgatatagt aataccagct gcattagaaa actctataac
    15481 taaagaagtt gctgaatcta taaaagctaa attagtttgt gaggctgcta atggaccaac
    15541 tactccagag gctgatgaag tatttgctga aagaggaata gttcttactc cagatatatt
    15601 aactaatgct ggtggagtta cagtttctta cttcgagtgg gtacaaaact tatatggata
    15661 ctactggtca gaagaagaag tagagcaaaa agaagaaata gctatggtta aagcatttga
    15721 atctatttgg aaaatcaaag aagagtacaa tgttacaatg agagaagctg cttacatgca
    15781 ttcaattaag aaagttgctg aagctatgaa attaagagga tggtactaag atttactctt
    15841 aataaataat aggatataat tatttaagat ataaaggggc tgtacatagt acagccctta
    15901 aattatgtgg cttacaatga agtaagctat ttttgtttta acttataaat aacttgataa
    15961 attatgtaat ttagaatgta ttttttacca ccacatgatt acaaattaga ggagttagat
    16021 tgaattttta gacatgaact tatgcatttt aaaagcaaag accttaattt aaagtatcta
    16081 gtattatttt taaaaatagt atattggttt aatccattta tatgtataat ggaaaaatat
    16141 atggatttgg attgtgaact ttattgtgat gagagagttt taaaaaattg tactgtacaa
    16201 caaaagcaag aatatgctct aactattgta aattcaatga aaagaagtac aaatttttca
    16261 aataaatttg tagctggatt aaataaacaa tctgatatta gaaaaagagt aataaacatg
    16321 ttcagtgaaa aacataaaaa tggtatctta agggctttga ttataagctt gttttcttct
    16381 attacatttt ttaaattcga ttcaactagt attattgaag agaatgattt cttagagagg
    16441 tcaagatata cgtttgaagg aaggcaagaa gacatgtttg taacaataga ttttatatat
    16501 gcagatgtac ctataaaact tagaaaagag catgaagaaa actgtagagt caatggaata
    16561 gtaccaaaag attcagattc aatagaaatt attcctagat tttataaaga ttgtatggat
    16621 ttaaaaaaat aagttagact taatattgat gttgatatta tgaatttttt atatttaagc
    16681 aattgaaaat tttattatag attcaatttt atatgtgttt aagtatgaaa tttatagata
    16741 gttgaaataa ttaaatatga ttgatgcata ggaatcatta ctaagctata attaattata
    16801 ggggagttta aataaattat gagttacaca atcataaaat gataaaaata gttatctgtt
    16861 acaaaaaatg tatcttttta attaataaag ataatatgaa aacttaaaag gcaaataaac
    16921 ttaaatataa aatactctta aataagatag gagaaaaatg tatgtctaac tttattctaa
    16981 atgggatttt tagaacagtt atagtaagta gtctaagcat tcttctgata ttgattttca
    17041 agaaaaatgt atttaaaaga tttagcaaaa aatttaatta ttatatatgg atgatagttg
    17101 ttattaaatt atttttacca tttacatatt atacttttac aataaatatc ttgagaagta
    17161 aaaaacacat taatattaat aacataaatt tagagggatt taataatgtt tcaactataa
    17221 gtaataatat tatattgtac acttggatta taactgtagt agtgtattta atttacacta
    17281 tatttaaata tataaaactt aaaaatttaa taaatgactt atcttatgat gttgatgata
    17341 gagagattgt aaatctttat aaaaatatat tagaagaatt taatataaca aaagatataa
    17401 aactcaaata ctcttatgaa gttgaaacac cagcattttt taattcatgt gtacttttgc
    17461 caccacatga gtataaattg aaagagttag actggatttt tagacatgag cttatgcatt
    17521 ttaagagtag ggacctttat ttaaaatatg taatcctatt tttaaaaaca gtatattggt
    17581 ttaatccatt tatatatata atggataaac atatagattt agattgtgaa ctttattgtg
    17641 atgaaagagt tttaaaaaat cgaaattcag aggaaaaaaa ggattatgct ttaacaattc
    17701 taaatgcaat gagaaaaggt tcaaatactt caaataaatt tatagctgga cttcataagc
    17761 aatctgatat taaaaagaga gttatgaata tgtttaatga aaagtacaag aatggtatat
    17821 taatggcatt aactttatgt ttattatctt ctattacttt tttgaaggtt aattcaacta
    17881 gtattgttaa tcttaatgta ttacctaaag gatttgaaga cttacgaact gttagcagta
    17941 tacgtttttc agttatagga tttacatatg cagatgctcc taaaaatatg agggaagaat
    18001 ataaaataaa ttgtgaatca ttaggtttga tacctaaaga ctctgataaa atagaagttg
    18061 gtatagaata ttatgacagt ctattgaatg attaaataaa tattatttta acagatatta
    18121 attataaagt tttgaatagt aatttgttga gaaataaata tatccttata aaaatagata
    18181 cttatatacc aagaataaaa aatagtcaag atagtacaca aggatatact tataaagaac
    18241 ttaaataagt gaaataaatt attaattata aggtttataa ttttaaaaaa ttagataaat
    18301 tcaggtgtaa aatactataa aacacaattc ggaaaagtgt atgttgaact tcatttaaaa
    18361 tggaatttca aagttgctat agtaagtagt ttaagcattc ttcttatatt aatctttgag
    18421 aataatgtat ttaaaaaagt tagtaaaaaa tttaactatt gtatattaat gatagttgct
    18481 attgatatat tatctaaaaa aattaagtat gaaaagatta ctgctaggac aatcttttca
    18541 tacttaattt ttaatattta tattatccaa aattttcatc tttttaactt agaatttgag
    18601 aatcactatt aggaaatagg ctttgattta tgtagggtta aaaatttcac agaatatcta
    18661 actttatact aaatccatca aaaaatatac gccatacaaa agcgcataaa aaaacacata
    18721 aaacaatatt tatgcgcact ttaacctcga atggtacaaa attctttact tttacagacc
    18781 catattatat aattaagtaa ataatgtata tttaggtgac atattggata agctaattta
    18841 tttattttat taatataata atactataaa agttatataa agtggtttac aaaaaagtta
    18901 cagatagagc ttttattaat gtattgtgta ttagtatttt atccttaggt acacttcacc
    18961 tacaaaatag aatcataaga taattatggg aaaattttag gaggtttatc gtgaagaaaa
    19021 agatattaat accagtattt gcatcagtta tggcattatc agtaagttca attgtaaatg
    19081 cagatgaagt aaatgattca tctcaaaata aggatgataa aacaaatact gaattaaatt
    19141 taggtgaata taaagaagta aaatataaag ttgcaaaaat aaaagatgga gtagctataa
    19201 agataagaga agaaggtcaa gttcaaaaca tagcttattc tggagatgaa tttacggttt
    19261 taggaactca aggagaatgg gttaaggtta aagttgaaga tggcgaaggt tggttagcta
    19321 ctagatatgt agatatatct gaaggtgtag gatatactaa cgctgataaa gtaaacttaa
    19381 gaaaagataa gagtgaaagt tcagaagtaa ttgaagagct ggaaaaagga agttctttat
    19441 tggttttgga agataatgga gattggttaa aagttaaaga tggggaaaca gaaggatatg
    19501 taaaatcatc ttatatatct gataaagctc ctgtaataga agagccacaa gtaaacccaa
    19561 gtattgacca aaatgtagat tctacaaata ataatcaaca aaacaatgca aatactaatc
    19621 aacaaaataa taattcaaat gtgccaacag ctaactctaa tgcagttcaa gctgtactta
    19681 acttggcata ttctaagcaa ggttgtccat atgtttgggg agcagaagga ccaaacactt
    19741 ttgactgttc tggatttaca caatatgtgt atagaaatgc agtaggaaag aatataccaa
    19801 gaacatctaa agcacaatct aaatatggac aaactgtaag taaagcaaat ttacaaccag
    19861 gagatttagt attcttcaca actaatggtt ctggttctgt tagtcatgtt ggaatatatg
    19921 taggtggggg taatatgata cactcaccat caacaggaaa aacagttagt gtaactagta
    19981 taaattcatc atactataca gcaagatttg ttacagcaaa aagaatatta taatcggttt
    20041 gtaatatgac aaattgataa atacataaat atatataaac gctctatatt atatttaatt
    20101 taatcatgga aacaaaataa tgattatatt ttaaatgtac tatagagcgt ttttgtatca
    20161 ctttaaatct aatcaagatt caagttaata tgactgttaa ataggagcct tttcatatga
    20221 tgattatttg tgcaatccct tgacaggata gggtaaaggt ggtaagctac taacagtaca
    20281 aaaatacttt taattttagt tcagagaggc taaaaaagga ggacgaaaga tgttaaaatc
    20341 aagaaattta atccaaccag aagacttttc aatagaagaa atagatgaaa tattagaatt
    20401 agctcaaaag ataattgaca atccgtcaaa atattctcgt atatgtgaag gaaaactatt
    20461 agctacatta ttttatgaac catcaacaag aacaagatta agctttgaat ctgctatgaa
    20521 cagattagga ggacgtgtag taggcttttc agagccaaat tcatcctctg catcaaaagg
    20581 tgaaactcta ggagatacaa tgaggatagt atctggttat gttgatataa tagctatgag
    20641 acatcctcaa tcaggtgcag cttcagaagc agctagatat acggaagtgc catttataaa
    20701 tgcaggagat ggcaaaaacc agcatccaac tcaaacactt acagacttac ttactataaa
    20761 atcattaaaa ggaactttag aaagccatac aataggatta tgtggtgatt taaaatatgg
    20821 aagaactgtg cattctttgg ttaaggctat ggcaagatat aaaaatacaa agtttgtatt
    20881 tatagcacct gaagagttaa aaatgccaga ttatataaaa gaagctataa agggacatgc
    20941 atattatgaa actaataatt tggatgatgt tataggaagc ttggatgttt tatatatgac
    21001 tagagttcaa caagaaagat ttgaagataa atcagagtat gaaagactta aaaactatta
    21061 tattttaaat aaagctaaat tagaaaaggc gtctaaagat atgttagtaa tgcatccatt
    21121 accaagagta aatgagatag acatagatgt agatagtgat gatagagctg tatattttaa
    21181 acaagctaaa tatggaatgt atgttagaat ggctttaata ataaaacttt taggtataaa
    21241 tgaagactaa tagttatcat ataatagtaa aacaaaggag attttgggat gtataaaatt
    21301 ctggaaaata tatatatagg cgaagatatg tatagaatga aagtaaaagg taattttgaa
    21361 ggtaaaatgg gacaattcta tatgttaaga gcatgggata cttatccagt actttcaaga
    21421 cctataagta tacatgatat agatgaagaa gggataactt ttctttataa agtagtagga
    21481 gaaggaactc aaattttgag taacctaaag gtaaatgata ctataaaatt ggaaggccct
    21541 tatggtaatg gatatgctaa ggttgatgga aaggtagctc tagtaggagg aggaatcggt
    21601 gtagctccac tatatttggt tgctaaaaat ataaaaaatt gtgatgcata tcttggcttt
    21661 agagaagatg ttatattaga agatgaatat aaacaagtat gtaataaagt atatacaaca
    21721 gtaggaaata cttttgtaac agatataatt gatgttgaga aatatgatta tatattaaca
    21781 tgtggtccaa ctccaatgat ggaaaaatta gttaagatgg tagaaggtac taaaacgaga
    21841 attatggtat ctcttgaaaa ccatatggct tgtggagtag gtgcctgttt agtatgtacg
    21901 tgtaaaacta atggaggaaa taaaaagact tgtaaagatg gtccagtgtt ctggggagag
    21961 gacgtgattt ttaatgggta atttaagtgt gaaatttgga agtgtagaat ttaaaaatcc
    22021 agtaataatg gcgtctggaa cttttggatt tggaaaagaa tataatgaga tttatgatat
    22081 acaaaaactt ggtggtataa gtagcaaggg tcttacttta aataaaaaac ctggtaacaa
    22141 tggtatgaga gttcatgaga caccatccgg tatgatgaat agtgttgggc ttgaaaaccc
    22201 tggagttcaa ggatttatag actatgaatt accttttttt agtaaactag acttagtcag
    22261 aatagctaat gttggaggtg ggacattaga agactactta ttaggggttc aaatgttaaa
    22321 tgacaagcct atagacatta ttgaattaaa tatatcttgc ccaaatgtca aagctggtgg
    22381 aatggctttt ggtataaaaa atgaagtggc aagagaagtt gttcgtgagg taagaaacat
    22441 aacgaaactg cctttagtaa taaaattatc acccaatgca gaagatattg taggaatggc
    22501 aaaagtttgt gaagaagaag gtgctgatgg agtttcatta gttaatactt ttaaagcaat
    22561 ggcaattgat ataaaaaata gaagaccagt atttgaaaat gtatatgctg ggttatctgg
    22621 accagctata aaacctatag ctttgagaat ggtacatgaa gtgtgtaaaa atgtaaatat
    22681 acctgtaatg ggaatgggcg gaataactaa agccacagat gctatagagt ttataatggc
    22741 aggagctact tgtatccaag ttggaactgc aaattttatg aatcctagaa taggtattga
    22801 aataatagat ggaattaatg aatttatgga tagagaagga ataaaaagtt tagacgaaat
    22861 aagaggaatt atataaggta gaataaatag tattttaaag ataaaaaata tagattaaat
    22921 aaacaataat tttataacat taacatggag gaaaaataat atgagtaaag tagatgtagt
    22981 ggatatatta aagaaaagtg atgcattgtt ggagggacat tttttattat cttcaggaaa
    23041 acacagtaat agatacgtac aatgtgcaaa agtattaaga tttccagaat atgctgctga
    23101 ggtattaagt acagttgttg aacaaataaa agacttagat atagacttag tagtaggacc
    23161 agctatgggt ggagtaatag tttcttatga gttaggaaga caattaggaa aagaagctgt
    23221 atttactgag agaaaagaca atacaatgga gttaagaaga ggatttgaag ttaaaaaagg
    23281 agcaaagata ataattgctg aagacgttgt aactactggt aaatcaacta tggagacaaa
    23341 aagagtatta gaagccttag gtggagaagt tgtaggtgtt gcatgtatag cagatagaac
    23401 taatcatgat ataggtatgc ctatatatag tgctataaaa cttgatattc aagtttatga
    23461 atctgatgag tgtcctttat gtaaggaagg aaaattacca gttgttaagc ctggaagtag
    23521 ggagttcaag gaattaggga tgtaataaaa acttaattat ttatagtgtt acttaaaaaa
    23581 tgtaaatttt ttagagtaaa aatttgtaat ataacatata acttaaaaat aaaaagcagt
    23641 tagccttata aatgaaggtt agctgttttt tttgttaaaa atatatttac aaaataagag
    23701 atagtagcag tacaatataa gtataaggta aaagtattat atattaggga ggggtaagta
    23761 tgaaaaatca attaaatgaa aatcataaaa aggttgtatt ttttggagta ggtgctgtag
    23821 gagctacttt tgcagaacaa ttttttaact ctaaatatga ttttaaaatt ctttgtgata
    23881 atgaaagaaa gaaaagatat ttagaagaag gatttataat aaatggaaaa aggtatgatt
    23941 ttgattatgt aactaaagat gagtataaac aagaggctga ttttataatt ataggtctaa
    24001 aatataataa tttaaaagaa aatataaaag aattagatgg attagttgga aaaaatacag
    24061 ttataatgtc tctgctaaat ggagttgata gcgaagagat aataggagaa agatttggaa
    24121 ttgaaaaaat ggtatattca tatgttacca atatagatgc aaagaaaatc aataataata
    24181 ttatacacac tactaatggg ataattgtat ttggtaacaa agataatagt gaagatagaa
    24241 aaactaatat aataaccgaa gtctttgatg atgtaaatat agaatatact ttatcaaaag
    24301 atattcaacg agatatgtgg tggaagtaca tggttaatat tggtgtaaat caaacttcag
    24361 ctatacttgg tgcaccttat ggagtttttc agagttctga gcatttaaga gaattagcaa
    24421 aatctgcaat gagggaagtt gttgctatag cacaagcaaa agacatatct cttacagaag
    24481 atgatgtgga acattcatta catagaatac tagaacattc aaaagaagga agaacatcaa
    24541 tgcttcaaga tgtggaagct catagactta cagaagtaga tatgttttct aagaatatct
    24601 gcaaacttgg aaaaaaatat aacataccta ctcctataaa tcagactttc ttttatatga
    24661 taaaagtaat tgaaagtaga ttttaaaggg tctttgtaag aaatattgat aattattgat
    24721 tttaaatttt attaatgtta tatactattt aagttactaa atatttttaa ctcttcaatg
    24781 aaaatagttg ctgcttttga taaagttata tcttttggaa atatatatga gaaatgtctg
    24841 ttgtagctgc ttccaagctc tatgacagac agctcattgt ttagaacagg taagcttgtc
    24901 actagattag agactattgt aattcctaaa ttatttctaa cagattcttt gacagcataa
    24961 ttacttccaa aaaccatcat actttttgga ataatttctt taacacttaa aaacatatct
    25021 aaataatctc tggttccaga accatcctcc ctgactatcc atttttggtt ttgaagttta
    25081 tcaaaactaa aatcttttaa taaatgactc ttgtatggaa gtgctaaaac catcttatct
    25141 tcaaaaaaat attcttgaat aaatgaaggg gaagagcaag tgccttcaat aagaccaatg
    25201 tctaaaatat aatccttaac atgagaagat acgattgatg tattttttat aaaaacttct
    25261 acatctatgt caggatactt tttagaaaat aatgctagaa aatttggtaa aatatactct
    25321 ccaatagtta aacttgcacc aatctttaag tgaccagtta tagcatctga aacttggctt
    25381 acatcatgat aagtaatatt taaaagattt aatatttctt tagctctttt gtacaagatt
    25441 tgtccacttt ctgttataaa aatggttttt tgtttaatag acctgtttat aagcacaact
    25501 ttaaaataat tttctagatt ttttatgtgt ttacttacac ttggttgtga tagatttaaa
    25561 tattccccag ctttagtaaa gtttttgtat tcaacaacag ctacaaatgt ttttaattct
    25621 tcaaacaatt ttttgtctcc tttacctaat gaaattttac attttttata tactttctac
    25681 agataattat actatatata ataaccatta aaaacattaa tcattacgat attatatatt
    25741 tattttactt atggttatta caattatata ctattgctat gaagaaaact atattaatta
    25801 taaggtaggt atattatgtt aaagaaaaaa agcagtttga cattaaaaac tataagggaa
    25861 atattaccag gactgtttgt atcagtatta gtaggttata ttagtatatt tatttctatt
    25921 ttaattccta aggtaggggc agcatcaatt tctatatttt taggtatgtt tgtaggaaac
    25981 ctatttttaa atcaaaaggt atttcaaaaa ggttataaat tttcagagac agatttgtta
    26041 tcatattcaa tagtactatt aggagcaaca ctcagtgtat ctaccttaat agacttaaaa
    26101 gtttcaggaa ttttatttat aatattgcaa atgacaataa caataatagc tgcactttat
    26161 ataggtaaaa aactaggatt tgaagaaaac tttagatttc taatggcaag tggaaatgca
    26221 gtatgtggtt cttctgcaat aggagcaaca gttccagtgg ttaatgcgac agataaagaa
    26281 aagggaattg cagtaactat tgtaaatgtt actggtatat ttcttatgtt tttacttcca
    26341 ataatatctc aatttttata tagccatgaa cttgtaaaaa cttcagcaat gataggtgga
    26401 actttgcaat caattggtca ggttgtagca agtggagcaa ttgttggaga aaatgtaaaa
    26461 gatttagcta ctatttttaa gatagtaaga gtaatatttc tagttgttgt tgtattagta
    26521 tttggacata tgaaaaatca atctaatagg gaaattcttg aagaagaaaa ggatgagata
    26581 aaaaagaaaa aagtgactat accatggtat gtaattggat tctttataac ttgtgcactt
    26641 ttttcaatga acattatacc acaagaagta tctgtgttgt gcaaagaaat aagtaacaaa
    26701 ctagaaataa tagctttagc agcaattgga ttaaaggtta atgtaaaaga tttagtgaaa
    26761 caagggaaag aagtttcttt atatggttta tttgtaggta tagtacaagt tgtatcagct
    26821 gtagttttaa taaaaatatt tatatagcat aaaaatagta tttgtaatat taatttgatt
    26881 aattaaaata atatgatact aataatttat aatataaata aaaaatgaat ttcgataagt
    26941 ttaagtgggt ataaacttat agaaattcat tttttattta aggtaaaaat ttaaagtaaa
    27001 atattatttt acataataat aaccttataa attttgaaat tacttatctt tgtgttaaaa
    27061 taagtaaaat gcacatatta gagctaagtt tttaagtaaa taaacaaaat gaaaatataa
    27121 atattaagga gatttggtat atgaatgttt atgaaaaagg taatggagtt atactagaag
    27181 gagtaacaga ttttgaccca gtacatatat ttgagtgtgg tcaatgtttt agatggcaca
    27241 aacaagaaga tggctcatac actggagttg caaaggggag aatattaaat gtcaaaaaag
    27301 agaatgataa aatatattta aataatacta atttaaagga gtttaacagc atttggtata
    27361 attactttga tttaggaact gattatacag aaataaagaa taagctaaaa aatatggatg
    27421 aatatttaaa taaggctact gaatttggat ggggaataag aatattaaga caagatggat
    27481 gggaaatgct tatatcattt ataatttcct ctaataatag gattcctatg atacaaagag
    27541 ctatagaaaa tttatcaaga aaatttggta agtatatagg tgaatatgaa ggtaatgaat
    27601 actatgcatt cccaacacca gaagaactaa ataaggcctc acaagaggaa ataagagcat
    27661 gtcaaacagg ttttagagat aagtacataa aaagtactac acaggcagtt atagagaata
    27721 atgatgaggt atctgaatat acaaatttaa gtactgagga ttgtagaaaa gagcttttaa
    27781 aatttaatgg agtaggacca aaagtatgtg attgtattgc attatttggt atgcaaaaat
    27841 atgattcttt tccagttgat gtttgggtta agagagttat gcaagaattt tatatagatg
    27901 aagacatgag tttacctaaa atgagaactt atggaatcga taaatttaaa gaaatgtctg
    27961 gatttgctca acagtactta ttttactatg caagagaact cggtatagga aaataaatta
    28021 agggggagaa attatgggag taataggaac aatatttctg ttctatttaa ttatatcata
    28081 tctagctgga gccataattt ctgtgattat attgcttgaa aatagagacc ctgcaaaaac
    28141 aatgtcttgg ctattgatgt ttattatatt tccaggtgta ggtttaatga tatatgctat
    28201 ttcaggtaga aatattagaa aaagaaaatt atttaagact caaaaactag ctaataatat
    28261 aaaagaaaag aaactatttg atacattaga aaagataaca gaaatagttg aattagaaaa
    28321 agaatctata aaacaaaata agcttttaag agatgaagag gatggtagtt atagaaaaag
    28381 ggtaataaat atgttgttaa agactggtat gtttcccttt actaaaaata ataaagtgga
    28441 tgtatttgta gatggaaatg aaaagtttaa aagacttata gaagatataa gagaagccaa
    28501 agaccatatt catttagagt actttatcat caaagatagt gaaataggta gggtgttaaa
    28561 agaagaactt ataaaaaagg ctaaagaagg cattaagata agaattttat atgatgatgt
    28621 aggatgctgg agattttggt ttaatagaaa atttttccga gaaatgaggg aagtaggtat
    28681 agaaattgca gcatttttac ctacaaaatt tcctataata ggagggaaat taaactatag
    28741 aaatcacaga aaaattgttg ttattgatgg aataattgga tatacaggtg gaataaatat
    28801 aggagatgaa tatttaggca aaaatgataa gtttggatat tggagagata ctcatattag
    28861 gattaagggt atttctgtat acatgcttca aatgacattt ctgattgatt ggtattatac
    28921 gacaaaagaa gtattagtga ctaaaaatta tttcccaagt gtagggaatg ttggtgaaag
    28981 tatgatacaa gttgttgcga gtggtccaga cagtgactgg gaagatattc attatgctta
    29041 tttttctgca atatgtcagg ctagaaaaaa tgtttatata gaaactccat attttattcc
    29101 agatgaaagt ctactaaaag ctataaagag tgctgctctt agtggagttg atgtgagaat
    29161 aatatttcct aaaattgcag accacaagat agtaaatata gcatcttatt catattttga
    29221 agaaatatta agagcaggtg gtaaagttta tttatataat aaaggattta tacattctaa
    29281 agtcgtaata atagatgata aaattgcttc tgcaggtaca gctaatatgg atttaagaag
    29341 ttttatgctt aactttgagg taaatgcatt tatctatgat gaagaagtta ttagggtaat
    29401 gacagatgat ttctttgagg atttaagtca ctgtgaagaa cttaatttgg aggtatttaa
    29461 gaatagaaat atcatacaaa aaatcaaaga atctgtagca agattatttt caccaatatt
    29521 ataaaaaatt attaaaaaag gtattgaaaa ttatgtgtga ttggtatatt ataataattg
    29581 ttagcactct attagataga gtgataataa ataaaaagta tatatataaa tctacatata
    29641 taagtagtat taatttaaaa ataactaaaa acataggcga actagtctat acttaatatt
    29701 ttaggaggcg tgaataatga aaataagacc attagctgac agagtagtaa ttaaaaaagt
    29761 agaagcagaa gaaaaaactg caagtggaat agttttacca ggagcagcta aagagcaacc
    29821 tcaaatagct gaagttgtag aagttggacc aggtggaata gttgaaggga aagaaataaa
    29881 aatggaattg acagtgggag ataaggttat attccaaaaa tattctggaa cagaagttaa
    29941 gatagaagga caagaataca caatactaag acagagtgat gtattagctg ttattgaata
    30001 aatatagaat aaatttatta ggaggggttt aaaatggcta aagaaattaa attttcagag
    30061 gaaacaagaa gagctttaga agctggtgta aataaattag cagatacagt aaaagtaaca
    30121 ttaggaccta aaggaagaaa tgttatatta gataaaaaat ttggttctcc acttataact
    30181 aatgatggag taactatagc aaaagagata gaactagaag atagatttga aaatatgggt
    30241 gctcaattag ttaaagaagt agcaactaaa actaatgatg tagctggaga tggtactaca
    30301 actgctacag ttttagcaca agctataata agagaaggtt taaagaatgt aacagcaggg
    30361 gctaacccaa tacttttaag aaaaggaata caaaaagcag taacagtagc agtagaagaa
    30421 ttaaaaaatc aatcaagaat agtagaaaca caagaggcta tatctcaagt tgcttctata
    30481 tctgctggtg atgaagaagt tggaaaatta atagcagaag ctatggaaat agtaggtaaa
    30541 gatggagtta taactgttga agagtctcaa actatgaata ctgaattaga tgctgttgaa
    30601 ggtatgcagt ttgatagagg atttgtttct gcatatatgg ttacagatgt agataaaatg
    30661 gaagcagttt taaatgaccc atatatatta attactgata aaaaaatatc taacatacaa
    30721 gaattattac cagttcttga acaaatagtt caacaaggta aaaagttatt gataatagct
    30781 gaagatgtag aaggtgaagc attatctaca ttagtagtaa ataaattaag aggaacattt
    30841 gatgtagtag cagttaaagc tccaggcttt ggagatagaa gaaaagaaat gcttcaagat
    30901 atagcaatac ttacaggtgc tcaagtaata tcagaagaat taggttatga tttaaaagaa
    30961 gctgatttat ctatgctagg tagagcttca tctgttaagg taactaaaga aagtactaca
    31021 atagtagatg gttctggaga taaaaaagct atagaagata gagtaactca aattaaacat
    31081 caagtagagc aaactacttc agattttgat agagagaaat taatggaaag attagctaaa
    31141 cttgctggag gagtagctgt tgtaaaagtt ggagctgcta cagaagtaga gttaaaagaa
    31201 agaaagttaa gaatagaaga tgctcttaat gcaactagag cagctgtaga agaaggaata
    31261 gtagctggtg gaggaactgc ttttgttagt gttataccag caataggaac actaattgag
    31321 agtttagaag gagaagttaa actaggtgct caaatagtta aaaaagcgtt agaagagcca
    31381 ttaagacaaa tagctataaa tgctggtctt gaaggtgctg taattgtgca aaatgttgtt
    31441 aattctgaag cagaaactgg atttgacgca ttgaatgaaa aatatgtaaa tatgatagaa
    31501 gctggtatag ttgacccaac taaagttagt agaagtgctt tacaaaatgc tgcatcaata
    31561 gcaagtactt tcttaactac tgaagctgct gttgctgacc ttcctgaaaa agaagatgta
    31621 ggaatgccag gaatgggtgg cggaatgcct ggtatgatgt aatttaaaaa atttaaaata
    31681 taaattttaa tataaagaac tatttcgact tagattttaa actctaagtt gaaatagttc
    31741 ttttgtatat atctaatttt tgtatatcta taaattcaat acacatattt agataatcag
    31801 tatctagttt gtaataatat tttagagtag tattgttatt ttttaggtta tgattttaga
    31861 tatatattaa ttaaggtata attgttgata gagaataaat caaatttaaa aggatgcgat
    31921 aatatggact taagaaaatt gcttgaagaa gttaaaaatg aaaatattga tatagatttt
    31981 gcgttagaaa agttaaaaga tttaccttat gaagaccttg gatatgcaaa tatagaccat
    32041 catagagaat taagaaatgg gtatccggaa gttatttatt gtgaaggtaa gagtgatgag
    32101 catattttag ggattattga taaaatgaat caaaaaagtt ctaacatatt ggggacaagg
    32161 tgcagaaaag aaacttttct gaaaattaaa gaaatctata atcatgctga gtacgaagag
    32221 gcgtctaaaa ttcttaagat tcaaaatcat gatatagaga atataggaaa aggtaaaatt
    32281 gtgattgcta cagggggaac ttctgatata ccagtagcag acgaagctta tcatacagct
    32341 aagtttttag gtaatgatgt tgatagaata tatgatgttg gagtggcagg tatacatagg
    32401 cttttaaata aaagacataa aatagatagt gctagagtaa tagtagccgt tgcaggtatg
    32461 gaaggtgctc ttgcaagtgt aattggtgga ctggttgatg ttccagtaat agctgttcca
    32521 acttctgttg gatatggagc aaattttgga ggattagcag cattactagc tatgttaaat
    32581 agctgtgcat ctggaatatc tgttgtaaat attgataatg gatttggagc aggatattta
    32641 gcatcaatga taaataaact gtaaatacat tgatataaat taaacaaaac tatataataa
    32701 aatttaattt ctattatatt tttactatta aaattgagga gacatatatg agtgaaaaaa
    32761 tactttattt tgatataata agcggtatat caggggatat gacccttgca agtttattaa
    32821 atttaggtgt gcctaaggaa atttttttgg aggaaattca taaactaaga atgagcgatg
    32881 aatttaatat aaacatcagc tcgaaaactg aaaatggaat agtaggtaca aaagtagaag
    32941 taattacaaa agaaaaacat acacatagaa atttagtgga tatatttgag gttatagata
    33001 aaagcactct aaacgaaaat gtaaaatcta aagcaaaaaa aatatttatg gtaattggag
    33061 aagcagaagc aaaagttcat ggaactacaa tagacaagat acattttcat gaggtagggg
    33121 ctatagattc aattgtagat atagtaggag cttctatatt agttgactta ctttgtgtag
    33181 ataaagtttg tgctagtaca gtgtctgttg gttcaggatt tgtaaaatgt gaacatggaa
    33241 ttatacctat acctgcacct gcaactatag aaattttaaa aggtgtgcca attaaattaa
    33301 ataatgtaaa tggagaatgt acaactccaa caggagctgc aatcataaaa gtcttgtgtg
    33361 atgagtttgt agatgagctt gaattttctc caaagcaaat tggatatggt ataggtcata
    33421 agaagtttga agtaccaaat atactcagaa ctgtattagg tgaaaaaaaa aagaagaatt
    33481 aatttatgaa attagtgcaa acattgatga tatgtcttca gaaatctatt cttatttgta
    33541 tgaaaaaata ttagatgaga aagcattaga tatttataca gagagcattt atatgaagaa
    33601 gaatagacca gcaacaaaag tatcaatttt atgtaatgaa tcagatttag aaaaatttat
    33661 taaaatatta cttttagaaa ctagtacttt tggagtgaga tataatgcat ataatagaga
    33721 aattctagag agaaaatttg taaaattaga tacaaaatat ggagtggtta cagtaaaact
    33781 agggtattat aaaggaaaac tagtcaaggc tactccagaa tataatgaat gtaaaactat
    33841 agcaaaaaat gaagatattc ctataaaaaa agtgtttgct gatataaatt ttagaataaa
    33901 agaagaattt agtgaaaact tattgacata agtaataaat tttgataaat taatattcag
    33961 ccttattaaa taaaagtaaa cagaaaaaaa tatataaaat ataaactcac tcgtatatgc
    34021 tcagaaatat ggtctgagag tctctaccaa gataccgtaa atatcttgac tatgagtgaa
    34081 attattatac caaaagacct agttaagtaa atgtgtaggc tgagttaaac tccctatgtg
    34141 ttggctataa gataaaggta ttttggaagc ctgtatagta atttcacttt tgctagaaat
    34201 tatggaagtt actatacagg ttttttgtgt aaaaagattt aatataattt agactgtatt
    34261 gtgttaaaat aaatatataa aaactatatt atacaaggag agatgtaaat ttatgaaaca
    34321 tgaattagta cttgtaatag attttggagg acaatataat cagttgatag ctagaagagt
    34381 tagagaaaac aacgtatatt gtgaaatact tccatgtact gcaagcatag aaagaataaa
    34441 agaaaaaaat cctaaaggga taatatttac aggcggtcca aatagtgcgt atttagaaga
    34501 ttctccaaca atatcaaaag aaatatttga actaggagta ccaatacttg gaatatgcta
    34561 tggtattcaa ataatgtctc atgtattggg tggagttgta agaaaaggta ataaacaaga
    34621 aaaagaatat ggaaaaacag ctataactta tggaaaatca tcattatttg aaggaataac
    34681 tacaaatagt gtatggatga gtcatacaga tttaatagaa aaagttccag aaggatttac
    34741 tatagttgca aatactaatg attgtccagt agcagctatg gaaaatgtag aacgaaacct
    34801 atatggagtt caattccatc cagaggtaga acactgtttg gaaggggaca agatacttac
    34861 aaacttctta tataatattt gtaaagtaaa aggtgactgg actacagatt cattcataga
    34921 agataaaata aaagaattaa aagaaaaaat aggcgataaa aaagctttat gtgctttaag
    34981 tggaggagtt gattcttctg ttgctgcagt tcttattcat aaagcaattg gggacaactt
    35041 aacttgtata tttgttgacc atggtttact tagaaaaaat gaaggaaatg atgtagaaag
    35101 aatatttaga gagaaatttg atataaattt aataagagtt aatgcagaag atagattctt
    35161 atctaaatta aaaggagttt ctgaaccaga agctaagaga aaaataatag gtgaagaatt
    35221 tataagagta tttgaagaag aatcaaataa attaggaaaa atggatttct tagtacaagg
    35281 aacaatctat ccagatgtta tagaaagtgg acatggaaat gctgctacta taaagtctca
    35341 tcataatgtt ggtggaatcc cagaagatgt agacttccaa gaaattgtag aaccattaag
    35401 agagttattt aaggatgaag ttagaaaaat aggattagag cttggtatag aagaaggatt
    35461 aatatttaga catcctttcc caggaccagg tctaggaata agagttatag gtgatgtaac
    35521 taaagaaaaa tgtgatatat taagagaagc tgatgctgtt tatatggacg agcttagaaa
    35581 agcaggttta tacagagaaa tatggcaagc ttttgcaaca ttaccagatg ttaagactgt
    35641 tggagttatg ggtgatgaaa gaacatatgc ttatttagtt ggtttaagag cagttacttc
    35701 ttctgatgga atgacttctg actggtataa gatgccttat gatgtattag aaagaatttc
    35761 taatagaata ataaatgaag ttgatggagt aaatagagta gtttatgata taacttctaa
    35821 acctcctgga actattgaat gggaataaaa tatagaatgc caaaaatcca cataaataca
    35881 ggatttgagg tctctcttac ttctatgtta tactggtttg atactatcaa tatttgccag
    35941 tatcttatgg attaataagc aaaaaacatc ctgctgaatg ataaattcag cggggtgttt
    36001 ttattttgtt ttagaactcc tttgctctga aactcgaagt atttaacact gatgattttg
    36061 ttatctttta gttccttttg tgtcatgctc tgaaagacaa attgatacaa taaaaaagta
    36121 atttcttaat cattgatgga gatatgtgtt tatgttactc ttgatggtaa tttgagtaat
    36181 attgttcata gctttttata ttcacttaat tagaaaacca tttggtataa tcataaataa
    36241 acttgatgat ataatagaaa agatttataa ttattagaag tatataaaag tattttatgt
    36301 ctatgaaatg tatgtctata aaacatatag atgacttttg tatattaatg tatgaatatt
    36361 gatattatag aagaattgag ttgtcaatga tactaaatca aatatttata gaagctggag
    36421 ggattatgag aaataaaata attataggaa ttactttttc acttgtatta ctaatgtctg
    36481 gatgtgcttc aaaacaaacc gcagaaataa acgtattagc aactactgat ttacatggag
    36541 ttatacctta tgagttaact tcttatgtaa aagaagaaag aaaaaaagat aaaaatctaa
    36601 ctttagtaga tgcaggagat ttttttgata gtggagaagt gtttggttct agcatggata
    36661 gttattttag tgctagatat aaagatggtg ataataacac tgaaagttat attgagacgc
    36721 ctatttcaaa agatatgaaa gaggtaggtt atgatgttgc agttcttggg aatcatgaat
    36781 ttatatccaa caataaattt tatctagata atatgatatc tgattttgag aagcaaaaaa
    36841 taaatatttt atcggcaaat acgtataaaa aaaatggaga tagttataca aaaccataca
    36901 taataaaaaa tattaataca cctgaaggaa acgtaaaact aggaatttta gggcttacta
    36961 taaaagaagt tggtgagagg aaacagtgga aagatggaaa acttgttgac tctaagtctt
    37021 tagaactaaa agaccaagag ggttacaatg gtgaattgta tatgaatgat ttagtagaag
    37081 atgctaaaaa gtgggttggt ataatggaaa aagagaagcc tgacattata gttgctgtgg
    37141 cacatacagg tgagaaacct aagaaaccta aaaacccagg aaatagaata caagacttag
    37201 ctcaacaagt tgatggaatt gatgctatag ttgcaggtca taatcatgtt caaattgagc
    37261 aacatgatta taaaaataaa tcaggagaaa atgttatagt tactgagcca ggaaagcatg
    37321 gggaatgtat ttctaagatt aattttaaat tagaaaaaaa caatgataaa tggaatatag
    37381 ttgacaaatc tagtaaatta attaaatttg aaaaaaatca agaaagtgat aaatttggag
    37441 aatttatttc ttcaattaat aaagtaagta aagataagaa agaaataaga ttatcagaag
    37501 taaagactcc tgaatgggat aaaatatatg tttttaaatc tggaacatct gcagatgata
    37561 tatataaaac aataggatat aaatggagaa atatatcatc tccaaagggt gatgacatgg
    37621 tgcagattgt tgtaatgaat aataataagc ctgttagcta tgtatatggt gaagctgaag
    37681 ttatgccaat taatataaaa tgtgatgaat cagagtataa agataatgtt gtaactattt
    37741 atcctaataa aaatgataaa tttaaaattg aaaaaggtaa acaagaatat agtattaatt
    37801 taaaacatat acaatagaaa cttttatctt atttaagttt agattgtact taaaataaag
    37861 tgtgtattat tttaaaaatt gatgataatt aaaatcacaa cattaaagaa tagtacacac
    37921 tttttatgct aaaaaataga atgttaaaaa attaaacctt taaattaaag tacattgctt
    37981 atattatcca atattatttt caaaggttgt gtaatatttt tatccttatg taatattgct
    38041 aacattttat tttccatatc tatcccatct aattcaatca atcgcaattt tttatgtaag
    38101 agtgaatcta ataataaatt ttctggcaaa atggttatac ctaaccctgc ttgtgcagct
    38161 ttaataagtg caaaagaatt aacactttcc caaacaggat aagctttttg gtttgaaaga
    38221 gataatacac tgtccaaagt attgcgaatg gcacttcctt gctcacgtaa caataacgga
    38281 aacgtgcata actgtcgtag agataaggct tgtttagtat tggtggtggt tatgcaatca
    38341 tacttttaat ccaagagaaa gtagtaaatc aaactggatg gataagtgag aaaatgttta
    38401 cagatattat aactatttca caaatgacac cagggccact ggctgttaat acttctactt
    38461 ttgttggact tcaaattgga gggttttggg gagcagttgc agccacttta ggttgtgtat
    38521 tatgtggtgt agtaatatct ctatttttat ataatttttt tcaaaagcat cagaactcta
    38581 cttatatatt tgaaatatta aatggtctaa aatcagcttc attaggttta attatctcag
    38641 ctgcggctac aattataatc cttgcattat ttgggacgaa taaagtgtac ttcaattcta
    38701 tatttgagat gctaaactgg actgcactaa taatcttttt tgttacacta ctgatagtac
    38761 gtaagtggaa aattaatcct attgtgatta taataataag tggtatactg ggaatatttt
    38821 tttatttata agtttttggt aagtagagga tatctatttt tttatatctt aaatccaaat
    38881 agccaataaa gtaaggccat ttggattttt aataaattct gaaaagataa tcagaaaccc
    38941 atataacatt taaattatat cactggtttt ctacaaacca atcataagct tcttggcaaa
    39001 atttctcact atctatatag taactattat gaacattatt aatttcaaca agtttctttt
    39061 tacattttag tgaattataa tagctatcaa aatattgggt tttaaaatat ctatcatgaa
    39121 gtgttttaaa gacaagagta ggtatgttga ctccatcttt tatcttacta tcttttgcaa
    39181 taaagcattc taacattgta ttaattatct ttgtactatt tttccaaata tgaggatttt
    39241 tcttttcaaa tattttataa aattcattat catagacttc attataacct ttatatttag
    39301 gtggttttac tgttatgtga aaattaggaa gaaacttaaa gaaaaagttt aataatttaa
    39361 cagtgagata ggtatagcct actcctgttg tgtttttata atcaacacaa gcaaactgag
    39421 caaaactttt taacttattg tctgaacatg cataatattg tgcaaacata ccaccaattc
    39481 ccgtattccc atatagatgt atgttggaag aataattttt ttctatgtat gtaatgacag
    39541 aatctaagtc ttttacaatt gaattgcgag aaaaatcttt ttcatatcca tcacttttcc
    39601 ctgttcctga aaaatcaaaa gcaaatatat ttacattatg tttggcaagt ggttcatatg
    39661 ctttttgcat ctcaagcgta gtgacaatag gagtatgtgt aacaacaata ttcatggatg
    39721 attttctggt aataaatgag ttacaaaaaa tcattgtatc tccatttggt atttttatat
    39781 gtttccaact catttgattt tcctttctct attataaaat ataataattt ttatgttctg
    39841 ttttatatat tattcatatt ttatcacaga taatatacta aagttaattt ttttattgta
    39901 cacctattat aataattctt ctataatata agacattcta taattttata tttaagttca
    39961 tgtgtattta attgttttta tataaaatgt ccagtaatac tatttggatt tatttttatt
    40021 tcatcaggag ttccagaagc aacaatttcc cctccattta ttccactgtc tggacctata
    40081 tcgataatcc aatcagaagc acgtataacc tctgtattgt gttcaataat taaaagtgaa
    40141 tgctgttcat ttacaagttt tctaaaagta attaacaaat tttctatatc tttaaaatga
    40201 agtccagtag taggctcatc caatatgtac agcattcgtt ttttagtttt tgtccctaat
    40261 tcttttgcta attttatcct ttgagattct cctccactta atcctaatgt attttgtcca
    40321 agctttagat atccaagtcc cacttcatct aataaggaga gttttctata tatatcagag
    40381 caatcgctaa aaaatgtttt tgcttctgct acttccatgt caagtatatc tgcaattgtc
    40441 tttcccttgt attgtataga cagtatttct ttttgatatc tcttaccttg acattcacta
    40501 caagttaccc attggtctgc catatattgc agaataattt ttgttttacc taatccttga
    40561 cagtttgggc attgcccctt tttgctatta aagctaaaat agctttcatc caataatttt
    40621 tgttttgctt gtggagtttc agcaaataga gaacgaattt catcaaaaat attgatatat
    40681 gtagcaggtg tagaacggct agattttcca ataggtgttt ggtccattaa gataaaatca
    40741 tcaatagcat caaatccagt aaattcagta taatttttat ctgggataga tttttgtttc
    40801 aatttttctt ctagagcagg aagtaaactg tgaaatacaa gagagctctt accagaacca
    40861 ctaacacctg taatagagca catacagttt aagggaattt ctacatcaat attttttaag
    40921 ttatttgcat ggcatccttt taagcttaac catttacttg gtataatttt attttgtgaa
    40981 cttattttat tgtatgtgct taaatattta cctgttatag agtttggatt ttttataatt
    41041 tcttgggttg taccttctgc aataatgaac cccccttttg taccagcact tgggcctaca
    41101 tcaataatat aatcagcaga cagtattgta tctttatcgt gttccacaac tataacagta
    41161 ttacccttat ctcttagctc ttctatcatt ttgatgatta aattatggtc tcttgggtgt
    41221 aaaccaatag atggttcatc taaaatgtag gttaagccta ctaattcact tcctagctga
    41281 cttgataatc gtactctctg cagttctcct ccagataaag ttggagctgt tctatctgtt
    41341 gatatatagc taagacctac ctttaataga taactaactc gaatttttaa ttctgttaag
    41401 atatcattta ccaaagagag ctcatttttt tgaagttgat ttggtaattc acacaaccaa
    41461 ttccataact gttctatcgt catttttgtt agttcaggga agcgataacc tttgattgta
    41521 gtgaatctag cctcaatgca cagcaattcg ccaccacatg tattgcaagg aattttgttc
    41581 atatattgat gcaaggtatt attttcagaa ctagattctc taaaaagtct ttgaatgtgg
    41641 ttgattgctc ctgaagcagg tcttctaatc tttgattctc gtccctttga ttcaaagcta
    41701 aattcatata tcttatcgtc tgtaccatat aagattgcat ctataaaatc tcttggtaat
    41761 tcattccaag gtatatctag gtctatattt ttatcttttg ctattgcata taattcacct
    41821 accatccaat taccatttgg ctttttcccc ttcaattttc caaaatagta agtagctcca
    41881 tctaatattg aaatagttgg gtcttttaca atcaattgag gattaacttg ataggtaaaa
    41941 cctaatccat tacaatcgtg acaagctcca gtatgggagt tagcattgaa ggttgaagta
    42001 tttatcttag aaaaaatagt ttgacaatgt ggacaataat tttttgtatt attctttttt
    42061 tctaatggaa ttttacaata tggacagtaa ctttttccga ttgatacaaa taacattctt
    42121 aaataatccc aaatgcttgt aagagtacca acagtagagc gaggattttg gcttcctttt
    42181 ttctgttcga tagctatagt aggggttaat ccctgaagta aatcaaattc cggtttttga
    42241 agctgttctg aaagttttgc tccattactt agattttcaa aataacgtct ttttccttct
    42301 tcataaatcg tatcgaaagc taaagaagat tttccactac cacttacacc tgtaataaca
    42361 gttatttgat tttttggaat tgtaacctca acatccttta aattgttttg ccttcctcct
    42421 tttaaataga tagagctttt attatgacaa agtgaatttt taattgattt atttattgat
    42481 tttgtaaatt tgaatttctt ttcgagttca agaggattgc ctaattcttt tatttccgaa
    42541 atgcctaata tttttaactg agaaaagatt gatttcaaat aatcttcagg caatttttct
    42601 attaacaaat taaggtcttc tatttttata tttccgcttg ataatatttc tgccatttca
    42661 tctaataaat ttttttctgc tcttgttaat tgattgtatt ttttggaact taattctgtc
    42721 cataaatccc atggaagcaa ttctaaacca atcatattat taaagtcatg tagaagatta
    42781 ccctttacag aatgccaacc tttccaattt ttattatatc caaagtcatc ttgatgagca
    42841 tgtccttgcc gacatcttat ccaggcttct gaaccagtta aaaaaccatc tgtttttccg
    42901 acatcatgag tgtcaaaatt aatttgaaaa taattttttt gtatgtcatc tatttgtgca
    42961 tctattctta tccatctctt tgttagagta tcatagtatt ctacaagcca gtggtcttca
    43021 taagtaagct cactttcaaa ataattagca aaacctgctc tcattctagc ctcaaaacct
    43081 cgatatctta ggagcgatac aagaagtaaa gaataatctc tgcacattcc aacaagcctt
    43141 tgttttgggt ttcttggaat agttagtggg ttagaattta tttcaaatat tctttttaac
    43201 atttgaggaa ttgtacgaag caattcctca tcagattgtt gtttattaaa ggatatacca
    43261 tataattttc cttggtctcc atgaattact aggctttgaa ccacttttaa taactcaatt
    43321 ggagtctttg gtaaatcttg atatttattt tcaaattttt taggatttgt gatgatgctt
    43381 tgatttttat agttatttat tttcatttat atttcacctc tctaaatgga tgatataccc
    43441 tgacatggtg tcatatgcaa gggcaattta aattttttgg ccaaaattta aaaataaata
    43501 aaaaatgata cagtgataaa ttgtaataca aatatagttt caaattgcat ataatataat
    43561 tatttaataa aaccattatc tatggaatgt taatgaaatg ttaagatggc attcttgaat
    43621 attaagaaat agaatactat aatatagtgt gaaggatttt tagtaaaaaa atttgtaagt
    43681 gttaatatac attaaaaaat agatttataa tttggaggaa aaaaatgaaa ttatcaaggt
    43741 ataagaaaaa tagtttagtt ctgtctataa ttttatgttc acttattatt tcaatccttg
    43801 taattactgt ttttaatacc gtaaaactac acaatatatc taataaacaa tctaaaaact
    43861 atttaaatga tgtatctaca cagattgtaa tgaatgttga ttctaaaatc aaatttattt
    43921 tatccgactt aagaataatg gcagatttta ttaagcaata tgaaggtgat agtcgatatg
    43981 agtatttatc taaaagaaag actagttata agtattatga tgttggaata atagatttag
    44041 aaggtaaagc tgagttttta agtggaaaaa agtttgactt aaagaatact gtttcctata
    44101 aaaaaggaat tgaaggtaaa gaatactcag aagtaataga gtcaatgggt tttgttcttt
    44161 atagtgtacc tatatttaat gataatcatg aagtatctag tattttaata ggtgtatcca
    44221 ataaagaaag tatgaatgag attcttaata tagataactt taatggaaaa ggaactattg
    44281 aaattattaa tagtaaggga aaacctcttt tcataggaaa aaatactgaa ttaataaagg
    44341 accttagcca taaatataag agttctggag atgaaccttg ggcacaaaag atgcttgagg
    44401 attttaaaaa tgataaatca gggaatatta caataacctc atcaaaaggt gtacaatgct
    44461 tattaactta tcatccaatt acaagaggtt taaatgattg gcattttctt ctcatagtac
    44521 ctgaagatgc tgtacttggt gaacttaata aattaaactc ttttacaata acaatgacat
    44581 ttataattac atgtattatt ggaattataa cattaatttt atatattata agaagaaaat
    44641 atgtaaatca aatagaaaat attgcatatt tagatagtat aacaaatggt ataaattcaa
    44701 ctaagtttag tatgctagtc aaacctttaa tttcagaatc acctgatagt acttatatga
    44761 tgatagcaat gaatataaaa gattttaagc taataaatga ttgtttcggt agtgaaaagg
    44821 gaaatatgac actaaaacat ctttacaata ttttgtataa aaacattgat gaaaatgaag
    44881 agtttgtgtg ccgtcatgat gcagaccttt tctatttgct tattaagaat agaccagtgt
    44941 tagaagccct ggagttatta tataaaatag aagctgacac aaattatttt aataaaaata
    45001 gggaaaatcc atacttttta agactatcag taggtattta cacaattgaa aatcataatg
    45061 aagatttaat tacaatacaa gaccatgcaa atacagcaag aaaaagcttt aataaaactc
    45121 atcaaagtga tttttctttt tatagtgata tagaaagaaa acgattaata tctgaaaagg
    45181 aaatttcaaa tttaatggaa aaagcccttg aaaataaaga attttttatg tgcttacaac
    45241 ctaaaattga tataaaaagt ggaaaaatta gtggagcaga gtctcttgtg cgttggaaaa
    45301 attcagaaaa gggcataatt tatccaagtg attttattcc tcttttcgaa aaaagtggat
    45361 ttatatgtaa gttagattta tatatactag aagaaacatg caaattgatt tctaagtgga
    45421 taaaagaagg taaagaagtg ttgagaattt ctgttaatgt atcacgtcaa catctgaatg
    45481 ataaattgtt tttagaaaaa tataagcata tatgcaataa atacaatgta ccaacatgtc
    45541 tgatagattt agaacttact gaatctattt tcttagaaaa tccagaagct atagatataa
    45601 tagaggatat tcattctaat ggatttaaat gttctataga cgattttgga tttgggtact
    45661 catcattagg gatattaaag gattttaaag ttgatataat taagttagac cgttcattct
    45721 ttgttagcaa aaataatata gaccgtggta aggtagttat taagtctatt attgaactta
    45781 gcaaaaggct aggtatgaaa gtaactgctg aaggaattga agaattagaa caagttgagt
    45841 tcctaaaaaa tgtgggatgt gattatattc aaggttatgt tttttcaaaa ccattattaa
    45901 tttctgactt tgaaaatttt gcatatgaaa ataataaaat taaaaatatc cattattaaa
    45961 tgtacaagat aaaaaattta ggcaagttat ataattaaaa atataacttg ccttttttat
    46021 ttatatattt aataaaaata tatttgcaga ttttgtaaaa ataattttca aatgttgtaa
    46081 gttgtggcta aagctttatt gtattattct gaatatagaa agatagttac tgtcttagat
    46141 aaaaactgaa acatacataa taatataaaa tttgctatat taataactct aattattttg
    46201 gaaggaggga aaatatgata agtgggagaa tgttactcat catgaatttt ctaaaaggaa
    46261 aaaataagac aagttacaag gatattagca aacaacttag tatagaagaa agaaaagtta
    46321 gatatgatat aaataattta aatattgttt tgcgttcatt aaacaagtca gtaatacaaa
    46381 agatgaacaa aggtgtgtta attattcctg atgacttcca agtagtatgt ataaataata
    46441 acgaatatgt attttcctta actgagcgag tatctattat gaaaattata tcaatgttta
    46501 aaatagataa tctaaactta gaaaaattaa gtaaagaatt tcaggtttct agaagttcaa
    46561 ttaaaaatga ccttaatgtt ttgtcaagtg aattagaaag aaaccaaata actattactt
    46621 atgataaatc ttttaaaata agtggagaag aagacattat atataagcaa agattgaaca
    46681 tattaaaatc gtattcttat ctttttggta aggaaaaatc tgatttaagt gtatttgaga
    46741 agtatttagt gaatgtaatt gaaaaaatat tcaaagggat ttatttgatt gatatatata
    46801 attggtctat gaatttatta ttgcaaatgg gatggacttt aaatgatgaa tcttttacat
    46861 ggtatgtgtc aaacattttc ctttttacat ggtatataca ttcagatgaa aaacatcctt
    46921 tagaatctgc ttcattaagt gagccgtgtt ttgaaaataa gtttgaccaa gaatttgaaa
    46981 caattattca aaaaaagttg actaaggaac aaatttttct gttaaagagt tttgtatttt
    47041 ttacaaataa atatgcaagt ttaaacgagg atatggattt gattagtaca gaaattatag
    47101 ttcaagacct aatttacaat atgtcagaaa tattagagat tagctttaaa gaagatatga
    47161 ttctttataa aggattactc aatcatattg ccccattgat agagagaatc aagcagaata
    47221 tacagattta tgaggaatta cttcatgtaa taccagataa atatcaatat gtacttgaag
    47281 ctactaaggt ttctattcaa aaaaacagag ttttaagtca aataaagaat gaaaatgaaa
    47341 caatactttt ggcaatacat ttcttaggaa gtatacatag aaatgagagg aataactaca
    47401 aaaatatatt gttagtttgt ggatttggat atggtgtaat tgctatgtta aaggatagtt
    47461 tagtaaatga ttaccagata aatatagtag agagtattcc atcatataag ttacaagatt
    47521 ataaagactg ggaaagtatt gacttcatta taacaacatc aaagatagta atagacttgc
    47581 ctaaaacaat tattgagata aatccatttt tacaagaaga ggattatttg aagtttgaag
    47641 aaaaagggat aaaaagaaag aatgtcttaa ctaattatat gtcaataaaa aaaaggttgg
    47701 actttttaga agaagatgcc caaaaaagag tattaagtat tatatgtcaa gaacttggat
    47761 acagtgatga gagaatatta tttagacaac ttaatttaag tgatttaata gggattgata
    47821 ccataaggat aattgatgga gatatgaaat gggaagatgc tgtaaaattt agttcaaaca
    47881 tacttgctaa ttgtgatttt gtatcagcac aatatgctga gaatattata gatattttaa
    47941 aaaatgtggg tttttatgct gtaaaagata acgaatttgc tttactacat ggcaatgata
    48001 gttcattagt caaagtaagt tcgataagtt tattaatatg taaagaagca gttagttttg
    48061 gagataaaaa ggttaaaatc atattttgcc tagcaagcag agataaaaaa gagcaaattc
    48121 ctgcaataat taatctaact aaaatggttt ataagactaa ttttattgct atgttagaaa
    48181 gtgcaaagac aaaagaagaa gcagaagttt taattcataa atatgagaag gaggtcactg
    48241 tatgaataaa ttagttaatg taaaatgttc atttaaaata catgttaatt caaaagaaga
    48301 agccattata tcgttagttg atgtagtgtc aaaagaagga tatttaatag ataaaaatca
    48361 atttttaaaa gatgttttaa agagagaaga aacattgtcg acttatattg gacatggtat
    48421 aggtcttcct catagtcaaa gtgtaggtgt taaaaactct tgtattacaa taggaaagct
    48481 tgatactcct attgaatgga cagaagaagg agaaaaagtg gatttaatat ttttgatatc
    48541 agtaacaaaa gacaatgaaa ataatcttca tttaaagatt ttatcaaaat tagcacgttt
    48601 attgatgcat gaaagtttta gaaatcaaat tagatgttca gatgaacaaa ctgtttataa
    48661 tcttataaaa gaaaaaatag aggaggaaga ttaaaatgag aattttaaag tttttgcaaa
    48721 aacatcttat gacagcaaca tcttatatga ttccatttgt ggttgcagga ggaatattat
    48781 ttgctttatc agtaacttta agtggacaag ctgctgttcc tgaaacaggc tggttggcta
    48841 aactgaatca aattggagct gctggcttgg ctttattcat tcctatatta ggtggatata
    48901 tagcatttag tatggcagat aaaccaggat tagctccagg tatgataggt gcatatttag
    48961 caaaagaagt aaatgcaggt tttataggtg gtatcatagc aggatttata gcaggatttg
    49021 ttgttttaca attaaagaaa attaaattag ctcctacaat gagaacttta ggttctatat
    49081 ttatttatcc tttagttggt acattgatta caggtggtat aattgtattt ttaattggag
    49141 aacctatagc ttcttttatg acatggatga caaactggtt aaatggaatg tctggtgttt
    49201 ctaaaattcc tttaggtgga atcttaggag gaatgatagc ctcagatatg ggtggcccta
    49261 taaataaggt tgctgctact tttgcccaaa ctcaagttga cacacttcca tatttaatgg
    49321 gtggagttgg cgttgcaatt tgtatacctc caattggttt aggattagct acattattgt
    49381 ttccaaaaaa atttagcaag gaagaaagag attcaggtaa agcttcacta ttaatgggat
    49441 gtgttggaat tacagaagga gctattccat ttgcaacatc agatccagtt agagtaatac
    49501 cttgtattat ggctgggtcg attgtaggaa atattatggc ttttttatta ggatgtttaa
    49561 atcatgcacc ctggggaggt ctgatagtgt tacctgtagt tgacaatagg ttggggtata
    49621 ttgcatcagt attaactgga gcagtagttg ttgcggtatt aatgaaatta gtaaaaaaag
    49681 acgtgaaaga agatgaagaa attgaagaag atttagatga atcaattgaa ttaatatttg
    49741 aagaattata aatataaatg gaaggaattt gtataaaaaa gtaaatataa aactataaat
    49801 ttaaaggaga taagaatatg aaaattgtag cagtaacatc ttgtcctagt ggagtagcac
    49861 atacttacat gtcggctgaa tcacttgaat tatcagccaa aaaatttggt atagaaataa
    49921 aggttgagac tcaaggaagc tctggaatag ataatgaatt gtcacttaaa gatattgatg
    49981 aagcaacttg tgtaatattg actaatgatg ttgagattag aaatatggaa cgttttaaag
    50041 gaaagaaggt agtaagaatg agtgtatctg agataattaa gaaatctgat gcattaatta
    50101 agaaaataaa agatactttt caataaaaat tgatttattt tacatataac tcaaagatgt
    50161 ttttaaagaa atttttatta aaagcatctt tgaaaatatc ttaaaaatag aataaaagga
    50221 gatatagtca tgaaaaagtt accaataaag actgtcgtgc aaagattact aaacttacaa
    50281 gaagagggga aaagtgcaac tcttttagga attggtccta tgtcaccaaa cttgttacaa
    50341 gcaagttttg aactagcaaa agatgatgat tttcctttaa tgtttatcgc aagtagaaat
    50401 caagtagatg cagatgaact aggtggcggt tatgtaaatg gttggaatca ggaaactttt
    50461 acaaaagata ttaagaaggt tgccgacaaa gttggatttg atggtttata ttatttatgt
    50521 agagaccatg gtgggccatg gcaaagagat aaagagagaa atgaccattt gcctgttgat
    50581 gaagcaatgg agttaggaaa aaaatcttat ttagcggaca ttgaagcagg ttttgaccta
    50641 ttgatgattg accctacaaa agacccattt gaaattggaa aagtaattcc actagatgta
    50701 gtactagaaa gaactgtaga attaattgag tattgtgaaa acgagagaaa aagacttaat
    50761 ctaccagaca taggttatga ggttggtaca gaggaaacca atggaggtct gacttcaact
    50821 gagacgtatg aaacatttat aactagacta aaggttgaac tcgataatag aggtttgcca
    50881 atgccaacat ttatagttgg tcaaactggt actttaacta gaaagacaga acaagtagga
    50941 acttttaatt ttagaaatgc ttatgattta gctcaaatgg ctaagaaata tggagttggt
    51001 ttaaaagagc ataatggcga ttacttagat gatgtaactt tattagaaca tataccatct
    51061 caaattattg ctacaaatgt agctcctcaa tatggtactg aagaaactag ggcatattta
    51121 aaattagcag aagttgagtg taaattagaa aaagagggct tagttgagaa aacttctaat
    51181 atcagacatg ttcttcttgt taatgcaatt gaatgtggac gttggagaaa atgggtagta
    51241 ggagaacaaa aaaatctaac tactgaagag atatttaagg atgaagtttt atctaatgaa
    51301 atactagata ttgcaggaca ttatacattt aataatgatg atgttaaaaa agaaatagaa
    51361 gtgctttatg ataatttaag taagaataat attgatggtc aaagatttgt tgtagaccat
    51421 attaaacgtc ctttgcgtga ttatgcagaa tgctataact taaaaggtgt tactacgagg
    51481 attttaaata aataatagga cttatagtgg tgagtattgt tatactaggt atttatagtt
    51541 ataattatac ttaccactat taaatttagg aggactaata ttttgattaa tttaattttt
    51601 gatgtagatg atactttata taatcaatta acgccttttt acactgcata taataaagtg
    51661 ttttcttcaa taaaggatat ttctattgaa gatttatata tgagtagtag aaagtatagt
    51721 gatgaggtat ttcatatgac tgaaaatgga gaaatgccaa tcaaagaaat gcatatttat
    51781 aggataatga aagcttttga ggagttggga aattctatta cagaaaaaga tgcacaaagt
    51841 tttcaagatg agtatatata tcaacaatca caaattacac taataccaga agttgagagg
    51901 attttaaatt tttctaaaga aagaaatatt aatctaggaa ttataactaa tggcccatca
    51961 aaccatcaaa gaatgaagtt aaagcagtta aatattgaaa actgggttga taaaagtaat
    52021 atttttattt ctagtgaggt tggattttct aagccagata ctaatatttt tagagtagct
    52081 gagaatgtta tgaatttaga tagagaaaat acatattatg tgggtgattc ttatagaaat
    52141 gatgtattag gtgctaaaaa agctggttgg aagagtatat ggttgaacca tagaggacat
    52201 gaggtagaag agttgtttta caaacctgat tttgtaattt tggaacataa ggatttgata
    52261 tctttattta taaaaatatg tagttataaa aatatgtagt aaaaaaatgt taataataga
    52321 attgtataaa ataattaata ataactatat aaaattatat gtttagattg tgagcaatct
    52381 attttatgtt aaaaatagat tatttagaag aaggggaaat cttaaaaaaa tttgaatatc
    52441 ccctttttat tatttaatta aaatgaaata gttagaaata tattttattt agtttagtca
    52501 ataacatttt gggattcttt ataactacat gttaactgtt gaataggttt atcatatggt
    52561 ttaacccatc ctttattaat acttaattct gtaagtgctg tgtgaccttc taccatttga
    52621 gttaatgaag ctgaatatat agctcttaat tcaggtgtac tacttgtcaa tgcagaatta
    52681 agatacatat tggcagatgc tttagcagat gaaagcatac ttaacattat tactttatcg
    52741 tctatataag tattgttctt aattagattt tctatcatat ttctcatgtt atctatacct
    52801 cctcagaaat tagtatttca ttttcaacta taaattgttg catagcttta attcttcctt
    52861 ctgttgctaa tatactagat tctgattgtc tttttaggtc ttcatctgat attaacatat
    52921 ttattgctct ttgcataagt aatccgtcag actccatttt tataactgct gctaaagata
    52981 ttttttcagt ttctgaaagt attctcattt aatcatctcc tatattgtaa tttatgcttt
    53041 aatagtatgt ctttcttttc aaggaaataa ccattacact tttttacagt attttatatt
    53101 ctctttatat caaaatttag tcgacctaat atattaataa taattttgta ggatatttat
    53161 cattaaatat ctataaaata aattatttga atattcataa agcaaaattt atttgtatgt
    53221 acttcttcaa gagtcaatat gagttttttc aaaaaattaa tttttatgat aatcattaag
    53281 ggctatattt ttcttaaagt tgtgattatc attattaatt tacaataaaa ttgccgaaaa
    53341 gccctctcct ttaggtgtag ggatgaaagg taaggtctta atataaaaaa agttagaata
    53401 atgcttgtaa tctaataccg ctactgatac cctatattta ggaggtgtta gtttttatgt
    53461 ataaatctaa caaaaatata gtttatgatt gcaaatatca tattgtattt tgccctaagt
    53521 atcgtaaacc tgttttagtt ggcgaagttg aaaagatgtt aaaagaaata ctaccatata
    53581 aagcagatga acttggagca gaaataatag aaatggaaac tgataaagaa catgtgcact
    53641 tattaatatc ttgtgaccct caatatggaa ttcataaagt agtaaaaggt ttaaaaggct
    53701 ttagttcgag agtattaaga gagaactttc cacatttaaa gtctagtatg cctagcatgt
    53761 ggactaatag ctattttgta ggtactgttg gttctgtgag tttagaagta gttaaacaat
    53821 atatagaaaa tcaacaagtt aggacaaaga aatgataaaa actcatagag tgaaattaaa
    53881 cctaactaga acacaatttg aattagtaag ggaaaagcaa atggaaagtg ctaactgttg
    53941 gaactacata gttaacttat ctaaagaata ctattttgaa cataaacaat ggattaaaaa
    54001 gaatgatata caaaagttaa tcaaaggtaa gtacaatctt catagtcaaa ctattcaagc
    54061 tatatcagat aaatttgatg caaatagaaa gactatatca gaattaagaa aaaaaggtaa
    54121 tactaaagca aaatatccat acaagactaa gaaattttat ataatacctt ttaaagctag
    54181 tgctattaat agaaatgcta aaggcaactt aaaattatca atgtcaaaag gcaggtattt
    54241 agaattagat tttaatgttg agaatataaa aactgctgaa atagtatggc gaaatggata
    54301 ttatttatac tacacttttg acaatgaatt aaatggagtt gtagccaaag gcactaatac
    54361 cgtaggtgta gacttagggg aaatacattc gatagctagt gtaacaaatg aaggtgtagg
    54421 gcttattcta tctaatagag aaggcagaag tattaaacaa tttagaaata agatgtatgc
    54481 ttatatatct aaaagattaa gtaaatgtaa aaaaggtagt agacaatcaa agaagttatg
    54541 gagattaaaa aataagataa gaagtaaaac agataatcag ttaatgaatt tatatcatca
    54601 aacaactaga aagtttatag acttttgtgt agagcagaag gtatgtgaaa tagttcttgg
    54661 ggatataaaa ggggttgaaa aagatactaa gaaaaagaaa agattaaaca gagttaatag
    54721 acagaaaata tctcaaatgg agtatggtcg aataaaggac tatataaaat ataaagcaaa
    54781 agagcaaggt attgaagtta agttagttaa agaaaactac acttctcaaa cttgcccaaa
    54841 gtgttctaaa aaacacaaac caactggtag aacttatagt tgtacttgtg gttatgaaac
    54901 tcatagagat atagttggtg cttggaatat tttaaataaa aagcataaat atggtttagt
    54961 agattttaga ataaatcata agcaaccaat aaatttaaaa gtatctaccg tttgagccat
    55021 gtgtgggcga ataactttaa ggtagtagtg gcgaagacac cgtccgaagt agcttggctt
    55081 tgtaaccacc tctgttgtac tgtttaagta taaataagtg tgttagccac caagaatccc
    55141 cttgctttag ctatggggag tgtgtcaata aaatacttta atgaaaaata gctaacttta
    55201 attgtaggat attcttaata tatttgaaat aaataaaaat attgaaggat ataatattca
    55261 attggtatat aaataataaa tgatagttaa attttacctt agaggctaat taggtgttta
    55321 gtcaaagcta atgcctttag aatacaaatg tattctaaag gcatttttac tatgtatttt
    55381 catttatatt actaaacatt atctattttt atatacattt ctatgtattt tattttcatc
    55441 aaatcggtct ataaactcat ttttttcttc actatatcca atagatataa gtgcataagg
    55501 aactaatttt aatggtaagt ctaaagtttg tctaacttta tttaccactt tatttttagg
    55561 aaatactcct gcccaacaag cagctagacc ttgattagta acttctaata ataaattttg
    55621 tgtgcaagca cctaaatctt gtatccattt accaggtttt aagaatttat ctctatttcc
    55681 aagcactact atacataatg gtgcaaattc tatatgcttt gctctatgct gtgactttga
    55741 gagctgtttc agcagttcct tatcatctac tataataaat tcccaaggtt gagcattttt
    55801 tgatgaaggt gcttgcatag ctgattttag tatttcagtt attttatctt cttctatatt
    55861 tttatctata tatgttctta ttgaacgtct attttttata acttctaaca tacagattct
    55921 cctttaaata aaattatttc tatttatata atatcattac tttaaatttt agctattact
    55981 tatataaaga ataaactttg tgttggtttt atctaagtaa aagtaacatt cagaactaaa
    56041 aaacaagact ataaatccaa agtattaatt aaaaaagaag taataaaaaa taatatacaa
    56101 gatttaaaaa agagtattgg gcttaaaatt taattagaaa accaattttg agataatctg
    56161 ttttttattt taacaaaaaa acacaaataa agttcgatac gtagcgaatg aaaaaattac
    56221 aagaaatatt ttttttaaaa aatttcaaaa aagagttgat aatatatgta tattaatata
    56281 aaatttaagg tgtataattc gtataataat acgaatgatt tgtagtgtaa aataacttat
    56341 aaacggagag gggaagtcta atgaaagtag cagtagttat gggttcaaaa tcagattatc
    56401 caaaattaga agaagggata aaactgcttg aaaaatatgg aatagaagtt gtagcaagag
    56461 cattatcagc tcatagaaca ccagaacaac tttcaatatt cctaaaagaa atagaagatg
    56521 atactgatgt aataatagca gcagcaggaa aagcagcaca cttaccaggt gtaatagctt
    56581 cacaaacatt aattcctgta ataggattac ctattaaatc atcaactatg gatggactag
    56641 actcactttt atcaatagtt caaatgccaa aaggaatccc agttgcaaca gttacaatag
    56701 acttaggttt aaacgcagct ttattggcat tacaaataat gactttaaaa tacccaaaat
    56761 taaaagagga tttgaaatca tatagagaag agatggcaca aaaggtgtta gaagacgaca
    56821 agaatttaag ggggtagcag aaatgttatt atatgaagga aaagcaaaac aagtatattc
    56881 tacagataat gaaaatgaat atgttgttta ttataaagat gatgcaacag catttaatgg
    56941 agaaaaaaaa gcagaaatat cttcaaaagg tatactaaat aataagatat caacaataat
    57001 ctttgaaatg ttaaaagaaa ataatataaa tactcacttt ataaaaagtt tatcagatag
    57061 agaaatgtta gttaaaaaag tagagatttt accattagaa gtaatagtaa gaaatattgc
    57121 tgctggttct atctgtaaaa gagttggtct tgaagaaggt gtagttttcg atgagccaat
    57181 ttttgaaata agctacaaaa atgatgctta tggtgaccca atgctaaatg atgattatgc
    57241 agtggcaatg aagttagcaa ctagagaaga gttaaaattc ttaagagaag aaactttaaa
    57301 aataaatgag ttactaaaag catttttctt aaaattaaac ctaaagttag ttgactttaa
    57361 aatagaattt ggtaaggatt ctgaaggaaa tataatattg gcagatgaag tatcaccaga
    57421 cacttgtaga ctttgggatg taaatacaaa tgaaaagtta gataaggaca gatttagaaa
    57481 agaccttgga gaccttgtag aaggttatac ggaagtactt tcaagaatga ataataaata
    57541 ggaggcaaat gtatgtgtgg agttttaggg atttactcta ataaagatgt aactaaagaa
    57601 ctatattatt ctttatattc tatgcaacac agggggcaag aaagctgtgg tttagctctt
    57661 ttagatgatg gagaaattaa gtacaaaaaa gatatgggat tagttggaga tgtttttaag
    57721 gaaaatgaat tatctaagtt aaaaggaaat atagggattg gacatgttag atattcaaca
    57781 gctggaggaa gtcatgtttc taactgtcaa cctttagttg gaagttgtag aaaaagacaa
    57841 ttagccatag ctcataatgg aaatctagtt aatgcaaatt atttaaaaga tatgctagaa
    57901 gaagatggat atatgttcca aactaattca gatacagaag tgattttata tatacttgct
    57961 agatattaca aaggggatat agtagaaagt ttaaaagtga caatggatta tataaaaggt
    58021 gcatatgctc ttgtaataat gagtcaagaa gaattggttg cagttagaga cccacatgga
    58081 ttcagacctc ttgtacttgg taaaaagggt gatgaatata tatttgcatc agaaaattgt
    58141 gcaatagata tacttggcgg agaagttata agagatgtag agccaggaga gataatagta
    58201 gtcaaagatg gagaactaaa atcatatttt tattcagaaa attataaacc agttaagaaa
    58261 agttgtatat ttgaacacat atactttgca agaaatgatg caactataga caatgtaaat
    58321 gcatatgaat ttagaattaa atgtggtgag agattagctc agaatgaaac tgtaaaggca
    58381 gatatggtag ttccagttcc agattcaggt tggccaggag ctattggtta tgcaaatgct
    58441 agtggattaa aaataagtga aggcttagtt aaaaatagat atgtaggaag aacatttata
    58501 aaacctacac aagaagaaag agaaatagca gtaaaaataa aattaaatcc tctttcaaca
    58561 ataataaaag gaaaatctat aattttagta gacgactcaa ttgtaagagg aactacatct
    58621 aaacaattag taaaatcttt aagagaagca ggagcaaaag aaattcatct tagaataact
    58681 tctcctccag tagcttactc ttgttactat ggaatagata ctccaaatcg ctctaaatta
    58741 attgcatcaa gtaacaacgt agaagaaatg agagaatata ttggatgtga tagtttaaaa
    58801 ttcctagata tagaaggaat gttagatgca acagaacata agtctacttt ctgtaaagct
    58861 tgttttgatg gagaataccc agttaagaaa attgataagg aggaactact ttcatgttaa
    58921 catataaaga atcaggtgta gatatagatg aaggaaatag agcagtagac cttataaaag
    58981 gtaaaataaa aggaacttat gatggaaatg tagttggaga tttaggtaac ttcagtggat
    59041 tatacagttt aaaagatttt gtaggtatga aagaaccagt tttgcttgca tctacagatg
    59101 gtgttgggac taagttaaaa atagctcaga tgatggacaa gcatgatact gttggaatag
    59161 atttagttgc aatgtgcgtg aatgatttaa tttgtcaagg agcaaaacca ttattcttcc
    59221 ttgactatat agctcttggg aaattagtgc ctgagcatat cgaaaaaata gttggtggaa
    59281 ttgcagatgg ttgtaaaatg tctggttgtg cactaattgg tggagaaact gctgaaatgc
    59341 ctggaatgta tggagaagat gactatgatt tagcaggatt ttctgtagga atagcagaca
    59401 aagaaaagat tgtttctgga aacaatgtta aatcaggaga tgtattggtt ggtatatctt
    59461 caagtggagt acacagcaat ggattttctt ttataagaaa gatattttta gaaacttaca
    59521 attataaaat ggaacaatat gttgaagaac taggaatgac agttggagaa gcacttttaa
    59581 caccaactaa aatatatgtt aaattagctt tagatgtatt agctaaacat gacataaaag
    59641 ctatagctca cataactggt ggagggctta tagaaaatat aacaagagtt atacctaaag
    59701 ggttaggact agatatcaat aaaaaatctt gggagaagcc tcctatattt aaaatgatag
    59761 aaggttttaa tgctgttgat gagagagaac ttcataagag ttttaacatg ggtattgggc
    59821 tagttttaat agtagataaa gaaaatgctg atgatgttgt aaactttata aataatagag
    59881 aaaatgacaa tgctgcttat gtagataaaa aatatagtga attattagaa gataaagctt
    59941 atataattgg tgaagtagta gatagtcatg aaggtgtaga attatgctaa atataggagt
    60001 tttaatatct ggtggaggaa caaatttaca agcagttata gatggtactg agtctggaga
    60061 aataaaaggt caggttaaag tagttatctc aagtaagcaa ggtgcttatg ggctagagag
    60121 agctaaaaat cataacataa aagcaatttg tgaaactgat gaagacaaga taatagaaat
    60181 tcttaaggaa aataaaatag atttagtagt tttggctggt tatttaaaaa taatcagccc
    60241 aaagctggtt aacgagttta gaaacaaaat gataaacata catccatcat taattccttc
    60301 attttgtgga gctggattct atggagaaaa agttcatcaa ggtgttatag attatggagc
    60361 taaagtaact ggtgctacag ttcattttgt agatgaaggt gctgatactg gaccaatcat
    60421 aatgcaagat gtagttaagg taaatcaaga tgatgatgca aagacacttg caaaaagagt
    60481 gttagaagtt gaacatagga ttttaaaaga aagtataagt cttttttgtg aaaataaatt
    60541 aaaacttcaa ggtaggagag tgtttataaa tgagtaagag agctttaata agtgtaactg
    60601 acaagactgg tgtagtggaa tttgctaaag agttaaataa attagattat gaaattatat
    60661 ctacaggaaa tacatttaaa acattaaaag aaaatggtgt taatgtaatg caagttgaag
    60721 atgttacaaa ttttccagaa atattagatg gaagagtaaa aacattaaat ccatatatac
    60781 atggtggtat actttataaa agagataaag aatctcatgt agaaactgta aatgaacaca
    60841 aaatacattc aatagattta gtagctgtaa atctatatga ttttgaagga actttaaaag
    60901 ctggaaaaag tcatgatgaa ataattgaaa atatagatat tggtggacca tctatgatac
    60961 gttctgctgc caaaaactat aaggatgtaa tagtagtagt agatataaaa gattatgatt
    61021 ctataataga aaaattaaaa acagatacaa tgacattaga agacagaaaa aaattatcat
    61081 ataaagcttt ctcaactaca ggaagatatg atgcgttaat atctagttat tttgctggag
    61141 aagttggaga tacgtatcct gacatattaa atttaacttt ccaaaaagaa caaactttaa
    61201 gatatggaga aaatccacat caaaatggtt tcttatattc acagtcaaat gcaaaaaatc
    61261 caatcttaaa ttatgagcaa ttaggcggta aagaactttc ttttaacaac ttaaatgatt
    61321 tacatggatg tttagaagta atgagagaat ttaaagatag tgaagaagta gtttcagtag
    61381 ctataaaaca tgctaattca tgtggggtag gtttaggaaa agatgctttt gaagcatata
    61441 caaaatgtta tgaagcggat aaggtttcaa tatttggagg aatagtagga ataacttcta
    61501 ctatagataa agctacagca gagaaattaa atgaaatatt cttagaaata gtagtagcat
    61561 atgattttga accagaagct ttagagatac ttaaacaaaa gaaaaatcta agaatattaa
    61621 aattagctaa aatagaaaat agtttacaac catatgaaat gaaatattta gatggaaaat
    61681 tattgataca agatagaaac aatatattag cagaaaaaag tgaaaatgta acaaaggaaa
    61741 aaccaacaga tgcacaactt aaggacatgg aatttggtat gagagtagta aaaaatatga
    61801 aatcaaatgc aattgcagta gtaaaaaatg gacaaactct agctttaggt tgtggacaaa
    61861 catcaagaat ttgggcatta aaaaatgctc ttgaaaataa caaagataaa gattttacag
    61921 gagctgtttt ggcgtcagac gcatttttcc catttgatga ttgtgtaaca ttagctcatg
    61981 aatatggaat atcagcagta gttcaaccag gtggctctat aaaagataaa gattcaatag
    62041 aagcttgtga caagtatgat atggttatgg tatttacagg aataagacac ttcaaacact
    62101 aaggaggata ttatgaagat attggttgta ggcggtggcg gaagagagca tgctatatgc
    62161 tggaaactaa gcaaagaaaa aaatgtagaa aaaatttatt gtgcaccagg taatgcagga
    62221 attgcaaacg tagcagaatg tgtaaatata ggtgatacta atatagaaga acttttaaaa
    62281 tttgccaaag aaaatgaaat aggtctgaca atagtaggac cagaagtacc actagttatg
    62341 ggaatagtag atgagtttga aaaagaagga ttaagagtat ttggacctaa taaaaaatgt
    62401 gctcaacttg aaggaagtaa agctttttca aaagaattta tgataaaaca taacatacct
    62461 actgcaaaat ataaagaata tacaaactta gaagaagcta tatcagaaat agatagtttt
    62521 ggatatccag tagtaataaa agcggacgga ttagctgctg gaaaaggtgt tgtaatacct
    62581 gaaaatagag aagatgctat agcaacttta aaagaaatga tgtcagataa gaagtttgga
    62641 gctgctggag ataaaatagt aattgaagag tttttaaaag gaatagaaac ttcaattcta
    62701 gcatttgtag acaatgatac aatagttcct atggcaagtg caaaagacca taaaaaagta
    62761 aacaactatg agcaaggtcc aaacactgga ggaatgggaa ctttttcacc tagtgaaata
    62821 tatacagaag aattagcaaa taaagtaaaa gagacagtat tagaaaaaac tttagaaggt
    62881 ttcaaaaaag atggacttaa ttttaaaggt attttatttg ttggtcttat gataactgaa
    62941 gatggagaaa aagtacttga atataatgta agatttggag accctgagac acaatctgtt
    63001 ttatttagat tagaaacaga tttacatgag ataatggaag ctatactaga taataagtta
    63061 aaagatatag aaataaacta tagtgatgat gaagctgtat gtgttatgct tacatcagga
    63121 gggtatccag acagttatga aaaagggaaa attataactg gtcttgaaaa cttggatgat
    63181 gatatagtag tattccatag tggcactaag atgtttgatg gtaatttggt taccaatgga
    63241 ggaagagtaa ttggtataac tgcaaagtca actagagtta aggatgcagc agaaaaagtt
    63301 tatgaaaaca taaagaagat aaactttgaa ggaatgcact atagaacaga cataggaaga
    63361 taatttttct aaaatggagg ataaggtatg ttgaatactg aaaataaaga ctcaatggtt
    63421 agaagagtat tggttgaaaa aagagaaggt tttgaccttg aggctaaagc tttaaaaaaa
    63481 gacttagtag aaagtttaca catagataat atagaaaatt taagaatatt aaatagatat
    63541 gatgtagaag gaatatcaga agaagtttat gaaaatgcag caaagacaat attctctgaa
    63601 ccaaatttag atgtagtata ttatgaagaa ataccaaaat taaatgatga aagagtattt
    63661 gcaatagaat ttcttcctgg tcaatacgac caaagaggtg attgggcagc tcaatgtgta
    63721 caaattgtaa atcaagggat aagacctgct attaatacag caaaagttta tatattatca
    63781 ggcaaaataa ctgatgaaga gttttctaaa ataaaagatt actgtataaa tccagtagat
    63841 agtagagaag catctttaga gaaaccagaa acgttaaaaa tggaaactga aataccaaca
    63901 acagttgaag tattagatgg atttatagat ttagatgaaa atggattaag aacatttgta
    63961 agtgaaaaag gattagcaat gactttagga gacttacaac acgttcaaaa atactttaaa
    64021 gatacagaaa agagaaatcc aactataaca gaaataaaag tattagatac ttattggtct
    64081 gatcattgta gacatactac ttttatgact gaaatagaaa atgtaaagat agaagatggt
    64141 aagtttaatg atatagtaaa agaagcgtat caaatgtatc ttaactcaag agacaatgta
    64201 tatgtgaaca gacataaaga tatatgttta atggatatag ccactgttgc agtaaaagaa
    64261 ttaaagaaaa atgggaaatt aaatgaccta gatgaaagtg aagaaataaa tgcatgtagt
    64321 ataaacgtag atgttgaagt tgatggtaag atggaaaaat atctagtaat gtttaaaaat
    64381 gaaactcaca accatccaac tgaaatagaa ccatttggtg gagcagctac ttgtttagga
    64441 ggagctataa gagacccatt atcaggaaga agttatgttt atcaagcaat gcgtgttaca
    64501 ggaagtgctg acccaagaac gactttagaa gatactttac ctggaaaact tatgcaaaga
    64561 aaaataacta cagaagctgc tcatggatat agttcatatg gtaaccaaat aggtcttaca
    64621 actggacaag ttgcagaagt atatgatgaa aactttgttg caaagagaat ggaaataggt
    64681 gcagttatag cagcagcacc aaaagagaat gtagtaagag aaagacctga agcaggagat
    64741 gtaatcgttc ttcttggagg aaaaacagga agagatggct gtggaggagc aactggttca
    64801 tctaaagaac atagtgaaga gtcaatctta acttgtagtg cagaagttca aaaaggagat
    64861 gctcctaacg aaagaaaaat acaaagattc tttagaaata aagaagttgc tcaaatgata
    64921 aaaagatgta atgattttgg agcaggtgga gtttgtgttg ctataggaga gattgctgat
    64981 agcttagata taaacttaga cttagttcct aaaaaatatg atggacttga tggaactgag
    65041 cttgcaattt cagagtcaca agagcgtatg gcagtagcca taaaaaaaga aaataaagat
    65101 aaatttatac aattagcagt agaagaaaac ttagaagcta cgcatgtagc tacagtaaca
    65161 gatacaggat atttaagaat gttctggaat ggaaaagcaa ttgtagatat aaatagagag
    65221 tttttagata caaacggagt aaaacaaact actgatgttc atgttactaa agtagatgaa
    65281 gaaaatacat tctttagctc taatgaaata gtaaaagatg ttaagtgtgc aagtatgaaa
    65341 gacaagttta caaaagtact atctgacctt aatgtttgtt ctcaaaaagg attagtagag
    65401 atgtttgata atacaattgg tggtaataca gtacttatgc catttggagg aaagtatcaa
    65461 gcgactccaa cacaaggtat ggttgctaag ataccagtac ttggaggaga aactaatact
    65521 tctacaataa tgacttatgg atacaatcca aaggtaggaa aatggagccc attccatggt
    65581 gccttgtatg cagtagtaga atctgtgtgt aaattggttg ctattggagg aaattatagt
    65641 acaacaagac ttacattcca agagtatttt gaaaaacttg gtaacaatcc agaaaaatgg
    65701 ggtaaaccat tctcagcact tttaggagcg ttttatgcac aaagtaaatt tgagatacct
    65761 gctataggtg gaaaagacag tatgtctggt acatttaaag atattgaagt tccaccaaca
    65821 ttagtttcat ttgctgttga cacagtagat gcgaagaaag tagtatctcc agaatttaaa
    65881 aaagcagact caaaagtagt aatgttatgt gtaaacaagg cagaaaatga tgttgtagat
    65941 tttgaggaat taaagagaaa cttagataaa gtaagagaac ttatacatgg aaataaagtt
    66001 ttatcaacat atgcattagg atttgcaggt gtaggtgaag caataagtaa aatggctttt
    66061 ggtaataaaa taggatttaa gtttagtgaa gaagctgaaa aagcatttac agataataaa
    66121 ttatttgagg ctagttatgg aaatatagta cttgaattag caaatgatga tttaagtatg
    66181 ttagaaggat acaattatgt tgtgattgga agtacagtta aagaagctag tatatttatc
    66241 aaaggtgaag aacttgcatt agatgaatta tataaagcac attgtagtac tttagagcct
    66301 atattcccaa ctaaaacaga agaagtaaaa tcaaagatag aaactataag ttatatatca
    66361 caaggagaag ctaaaaaatc atcattaagt atagctactc caagagtatt tataccagca
    66421 ttccctggaa caaactgtga atatgactct gcaagagcat ttgaaagagc aggagctaat
    66481 gcaagtataa gagtatttaa gaatttaact tataaagaca tagaagattc tatagataca
    66541 atagtaaacg aaataaaatc ttctcaaata ataatgttac caggtggatt tagtgctggt
    66601 gatgagccag atggttctgg taaatttata gctactgtat ttagaaatcc tagagtgcaa
    66661 gaagctataa atgaattttt aactcaaaaa gatggactaa tgttaggtat ctgtaatgga
    66721 ttccaagtat taattaaatt agggttagtt ccatatggag aaataagagt tccaagtgaa
    66781 agtgctccaa cacttactta caataatatt ggtcgccatc aagctaagat tgctagaact
    66841 agaatttcat ctaataaatc tccttggtta gctcaaacta atgttggaga tattcataat
    66901 atagcaattt ctcatggaga aggtaagttt gttgccagtg aagatgttat gagagaatta
    66961 attgctaatg gacaagtagc aactcaatat gttgacttta ataatgaagc tacttatgat
    67021 attgagttta atccaaatgg ttcattctat gctgttgaag gtataactag tgctgatggt
    67081 agagtgtttg gtaaaatggg acattctgaa agaattggtg aggaagtata taagaatatt
    67141 ataggtgaaa aagaccaaaa gatatttgaa tctggagtta aatattttag ataaagcttt
    67201 gatgtttaat tgatagctag aatatataat ttagatattt agatttaaag agatgtaata
    67261 atatgatgat aatcatttaa tattacatct cttttttatt tatctaagaa ataataagtt
    67321 caacctaagt taaaatacaa gctgtgttat aattaattat taagtaaaat tgaatattta
    67381 ttggagggca acataattaa tgaaaatatt aataacaggg tctaatggtc aattaggaaa
    67441 agaattggtt aaccaattag aagcaatcaa tcaaagtata aaccaaccaa aatatgttat
    67501 attagctaca acaagaagtg atttggacat atccaatcag actaatgtag ataattttat
    67561 tttgcataat aaacctgatg tagttgtaaa ctgtgcagca tatacaaagg ttgatgcatg
    67621 tgaagataat atcgaaattg catacaaaat aaatgcttta ggagtgagaa atctagcaat
    67681 agcatcagaa aaagttaatg ctaagcttat tcacatatca actgactatg tattcaatgg
    67741 tttttctaaa tatccatata gggaagacaa taaaactgaa cccaattctg tatatggaaa
    67801 aagtaaactt atgggagaaa aatttgttga acaattctca cataagtact ttatattgag
    67861 aacagcatgg ttatatggta atgggaataa ttttgtaaag accatgataa aactttcttt
    67921 agaaaataaa gaggttaatg tggttaatga ccagtttgga actccaacaa gtacagtaga
    67981 cttagcaaaa attataataa gaatcatgga aacagaacat tatggagttt atcatgctac
    68041 atgtgaaggt gagtgtagtt ggtatgattt tgccaaaaag atatttaaac taaaaaatat
    68101 agatataaaa gtaaatccaa ttaagagtaa cgaatttaaa tgtaaggctc caagaccact
    68161 atattctgta ttggataatt ttatgttgaa gttaattggt ttaaattctt ttagaaagtg
    68221 ggaagaatcc attgaagaat atttagaaag atatgatata aatgaaaagt aaatgtatta
    68281 ttttgagaaa agaaaataag atattataaa aaatataaat atttctttta tttatccgat
    68341 aatcataata tgacaaaaac aaatttaagg atggaaaaag atgaaaggaa ttattttagc
    68401 aggagggtct ggtacaagac tatatcctat aacaaaatgt atatcaaaac aaacacttcc
    68461 aatatacgat aaaccaatga tatattaccc tatgtcggtt cttatgttgg cagggataca
    68521 agatatatta ataatatcta caccaagaga tataaaagca tttgaagaat tatttggaga
    68581 tggaagttca ctagggctta acataacata tgcaattcag gagaaagcaa atggaattgc
    68641 agaagcgttt ataataggag aagaatttat aggaaatgac agagtgtctc ttgtattagg
    68701 ggataatata ttttatggat atggatttag tgaaaggttg gagaatgcag ttaaaagaaa
    68761 aggagcaact atatttgggt atcatgtaag taatccaaat tcgtttggag ttgtagaatt
    68821 tgataaggat tttaatgtat tgtcaataga agaaaaacct acagttccta aatctaatta
    68881 tgctatacca ggattatatt tttatgataa tgatgttgta gagatagcaa agctagttga
    68941 accgtcagat agaggtgaat tagaaataac ctctataaac agtgaatatc taaaacgagg
    69001 aaaactaaaa gtggaacttc taggaagagg tatggcttgg cttgatactg gtacacataa
    69061 aggtctattg gatgcttcta attatgttga agtggttcaa acaagacagg gactgtatat
    69121 agcatgttta gaagagattg catatacaaa aggatatata agtagagaac aattaatgaa
    69181 actagccaag ccactgataa aaactgaata tggtcaatat ctattaaaat tggctagtga
    69241 agatatgtaa tatggtagat aaaatttatt ataaatttta ttaagggagt ttattataat
    69301 gggaaaaatc aatgttataa agactaaaat agaaggatta tatatagtcg aaccaaatgt
    69361 attttatgat gaaagaggat attttatgga aagctataat aaaaaggatt ttatagagca
    69421 gggtcttgat atgtgtttta ttcaagataa tgagtctagc tcaagaaaag gcgttttaag
    69481 aggaatgcat tttcaggtta aatatcctca aggaaaatta gtcagagtta cagagggaga
    69541 agttttcgat gttgcagttg atttaaggaa agattcacaa acatttggga aatgggaagg
    69601 tgtaatattg tctgataaga ataaaaaaca attttatatt ccagaagggt ttgcacatgg
    69661 atttttagtt ttatcagaaa aagcagtatt tagttacaaa tgtacaaatt attattaccc
    69721 agaatttgag aatggcttta tatggaatga caagcaaata tctattgagt ggcctttaaa
    69781 aggaattgaa gaaatatttt tatcagaaaa ggacaaaaaa caaaaaagtt ttaaagatat
    69841 ttgtacaaga cgttaataaa aatttattag aattaacatt taggagaaaa aatatgaaaa
    69901 aaatactgat aactggagga gcaggattta ttgggagtaa ttttatacat tatatgctta
    69961 acaagtatgt agattatttt attgttaacc tagacttgtt gacttatgct ggtaatttag
    70021 agacattaat agaaatacaa gacaattcca attataaatt tgttaaagga gatatttcaa
    70081 atagggagca ggtgtataag ctatttgaag aagaaaggtt tgatatagtt gttaactttg
    70141 ccgctgaatc tcatgtagat aggtcagttg agaatcctga tttatttatt aaaacaaaca
    70201 ttataggaac acaagtactt ttagatgcat ctataaaata tggagttaaa aggtatcatc
    70261 aaatatctac agacgaagtg tatggtgatt taccaattga tagaaaggat ttattcttta
    70321 cagaacaatc ttctatcaat ccaagttctc catattcagc ttctaaagca tcagcagatt
    70381 tattggtaag ttcttattat agaacatatg gattgttaac aactatatct aggtgttcca
    70441 acaattatgg gccatatcat tttcctgaaa aattgattcc tcttatgatt ttaaatgctt
    70501 tggaaaacaa acaattgcca gtatatggga atggggaaaa tgtaagagat tggttacatg
    70561 tatatgacca ttgtactgct atagacttaa taatacataa aggaaatata ggggagattt
    70621 acaatatagg aggtcataat gaaagaagta atctagaagt agtaaaaatg atattaaatc
    70681 ttttaggtaa atctgaagag ttaatatcct atgtaaatga tagacctggt catgatttaa
    70741 gatatgctat tgatgcaact aaaatagaga atgagttagg ttggaaggca aaatatgact
    70801 ttgatttggg tataaaagaa actgttaagt ggtatataga aaatgaatct tggtggaaag
    70861 ctgttttatc agtataactt taaaatttag aaaggggcgt tttatattga atgagataag
    70921 ttcactaatt aatatattag cattgactca attatctggt agtaatacta caaatcaatg
    70981 taattgtaca tataataatt catctggatt tgatatgatt atgatgacct tgttaaaagc
    71041 attatcacaa aataatcaac atacttctaa tagctacaat ttattgtcta attctgagaa
    71101 tttatttaat gaacttgata atgtagtaaa taataccact agtagattta tagatgttga
    71161 tacaaaagat aaaaatgtaa agttgagaat tgaaaatgct gtagatcaag catcaaaaaa
    71221 atataacgta gattcaaatc ttataaaagc aataattaaa gttgaatcag attttaatcc
    71281 aaataccgtt tcttctgctg gtgctaaggg tcttatgcaa cttatgccag aaaactgcag
    71341 agacttagga gttacagacc cttttaatat agaacagaat atagatgctg gaactagaca
    71401 tattaaggaa tacattgata tgtttggagg gagcatagaa atgggattga tggcatataa
    71461 tggtggtcct ggaagaatga aaagtagagg agtagaatca atctctgacc tgtataaaat
    71521 gccaaaagaa acacaaaatt atattcctaa ggttatgaaa tattatagag ggtaggcttt
    71581 attatgggaa taaatataga taagctaaac ataagtccaa gtataaatat ggaggttaaa
    71641 aaactaaaag agagtaataa attttctgac aaattaaact ctttaaaaca atcttcttca
    71701 ttggaagata taaaacgaaa tttggaaagt gtaaaaaagg caggagaaag gcttgtactt
    71761 actcaaaact atggcgatat tagtatatat aaaaatgcag taaaagaata cctaaaatct
    71821 gttgtagata atatgtattc acttgataaa aatagtagct tttgggagca tcagtattat
    71881 aagaatgtaa agattgttga tagtaaactt gaggatatga ctagtaagtt aattagtgaa
    71941 gaaaaagaaa acatagatat tgtttctact gttgacatga tacaaggctt attgatagat
    72001 atgtatagat aaggttatac aaggagaaaa attttatgaa tagcaaaaaa gaggatatat
    72061 atgaattgaa ttttgggcaa ttaatagaag aaaaatctgg tgttatagaa gaaaatcaaa
    72121 atgtttttaa tgcaaaagta aatgtagctg tttctatagg aaatacaaca gaaacaataa
    72181 aaaatatatt agatttaaaa gaaggctcta taataaaatt aagtaagaat gtggatgaaa
    72241 aattagatat atatgcaaac gatagattgt ttgcttatgg agaaagcatt attacaaatg
    72301 agaggttatc tgtaagatta tctaaaatag aagatccaga tgtaaattag cattttaaat
    72361 agtatccctt taggctattc tgtatgagtt tagctaaggg gatattttta taaaaaattt
    72421 aaaatatgtg tgaattatat aaatattttt attttatgag cgataactaa attataagta
    72481 tgtaattttg gaggtgaaac tatggatatt aaaaatgtaa gttcaaatat tgtagtgaat
    72541 aattatttaa agaatacatc tggtataaaa aaagtggaag aggttaaaaa aattaataaa
    72601 acagataaga tagagttatc taaatttgca aaggaaatgg caagtgtgtc aaatatgagt
    72661 gatgagaata ttagaaataa aaaagtcgat gaaataaaaa atgcattaga aaatggaact
    72721 tacaaaataa aaccaaaaga aattgcgaaa aaaatgatag aggatatgcg aggataaagt
    72781 catgattaca gacttaaaag ttataatata tgaagaaaaa aatataatta gtaagatgat
    72841 ggaattatta aaagaacaat ttgattatat agttgaaaaa gacttagaaa atttaaatat
    72901 gttaaatcct aaactagaag atattagcag ggagcttgca tccatagaaa taaagagaag
    72961 acaacttttt ggtgatgata tttcaatgag tgaagttgtt gaaaatagta atgatggata
    73021 cttaaaagaa atatatacag acttgaaaca cattcttgct ttagctaaaa atcaacaaga
    73081 atcaaatgat tctctaataa agaaagaact tatttttacg aaaaaaatga ttaatttcat
    73141 aaaaccagct gataagcaaa ctacaactta taattcttat ggaaatatta gaaaataaat
    73201 attaggagga gaaatatggc aggattattt tccattttaa atacagctaa ttcaggaatg
    73261 aatgcgcacc aaaaagcaat acagacaatt tctcataata taagtaatct agatacagac
    73321 ggttattcta ggcaaaggac cgagtttgcc acaaatagtc caatgtatat gcctagtttg
    73381 agtaattcaa ttgcaagagg acaattaggg actggagtac atgtaacgga tgtaacaaga
    73441 gctagaaata gtttttatga ttaccaattt agggcagaag ctcataagta tggtaagaca
    73501 gtttcaaaat atgattatta caatactata gaaactatac taaatgaacc atcagactat
    73561 ggaatatctg caggtataga tgattttttt aaaggatggg agtcattatc aaaggatata
    73621 aatagtgaca gtaaaaaaag tctagtggta gaaaacgcat ctaatttagc aactttaata
    73681 agtgaaagtt ataagaagct tgataagtta aaagaagata tagattctaa tatagacact
    73741 gagataaaac aaataaatga catgttaaaa agtcttgaag atttaaataa atctattgat
    73801 attatatctg gttctggctc tacaccaaat gatttacttg atgaaagaga tagaatttta
    73861 gataacttga gttttaaact agactttgaa aatagtgatg ttaaaaatat gcttgcagat
    73921 ggtaaattag aacttaatga attaaaaaat ccagatggaa cttggaaaac aggtatatca
    73981 gggaccttac aaggcttgtt tgaaatgcat ggtaagattg atacatataa aagcgattta
    74041 aaagatgtat ctgatggatt agctaaacag ataaatgatg tttataatac gtctgcagga
    74101 ataacagtaa cagatttttt tataacttca aatgtagatg gtgaagatat tataaagata
    74161 aatccagcta taaagagtaa cccaaatgaa ttaaagctta ctgctgatga agcttcaaaa
    74221 attgctaagt taaaggatga aaaaatagat attggggtgg ctggtggaaa agtaagtaca
    74281 ataagtgacc actataaagc ctttgcagaa tcaatcggtt tagattctca aaaagtaaat
    74341 caagatgaag caaatcaacg taaaattata aataatattg ataactcaag aatgagtgtt
    74401 tcaggtgtat ctttggatga agaaatgaca gagcttataa aaatacaacg ttcatatcaa
    74461 gctagtgcaa aagttatgtc aacagctgtg caactactgg atgttgtaat aaatggaata
    74521 atttaataga agggggaatt tataatgaga gtcagtacag gtatgatgtc tagcagctat
    74581 ctaaactcac tacaagataa tctacaaaga ttggataagg ttaatagaca agttaataca
    74641 acaaaagaaa taaacaagct atcagataat ccatataaag caataaagat attaaactca
    74701 aaaagtgaaa taaagactat ggagacttat gttgagaatt gtaaagatac agggaattgg
    74761 ttagaaacta ctgatactgc attagatcag cttggaaaat tattatcaga cataaagaaa
    74821 actttggtgg caagtggtga tggtgcatac tcagatgatg aattaaagac tcttagtaat
    74881 gaaactaatg aaaaaatgaa agaaattgca aatgctttaa atgcaacaca tgaagggaag
    74941 tacatatttt caggttcaaa tacgggggta ccacctgttg aatgtataga taatgctgat
    75001 ggttcagtga gtttaaagtt taattctagt ctaaatctta ataaattaaa tgactctttg
    75061 agtatggata tagctcaagg aataagtgta gattataacg ttaaattgag tagccttgga
    75121 tttgacccaa caaaaactga cccatttgaa gagttaaata acatatcaaa aaaattagca
    75181 aatccagatg ctgatgctat aaaagagctt acaacaactt gtttgggcga tatggaacaa
    75241 ctaatagaaa atacagtaaa tgttaggtct atatatggga caaaagcaaa tacagtagag
    75301 gctatgaagg aaaaaaacga tgatagtttg atacagttaa aggatatttt gtcacaaaat
    75361 gaagaaatag attatggtga aaaacttgtt caattaaagg cagcagagtt aacttatcaa
    75421 gcttcactac aaacaggagg aaagttattt aatgtatcta tattagatta catataataa
    75481 aataacgcag atatgatgaa ggttacatta aaaaaaggta tattaggttt tgaaaattta
    75541 aaagaatatg agcttttaga tatagaagat aatgattatt taaaagaatt taattctact
    75601 gaagaagaag gtataggatt tgttgttgta tctccatttg agattatcaa tgaatatgaa
    75661 atagttttaa atcaggaaac aatagaaaaa ctagaagtga aatctccaaa ggatgttgta
    75721 ttatttaata taattactct tggtcagaca tttgaagaat caactgtgaa catgaaagct
    75781 cctatagtga taaatataaa aactaatttt ggaatgcaaa taattttaca ggatgataaa
    75841 tattcaataa ggcatccatt attgagaggt gatagtggat gctagtaatt tcaagaaaaa
    75901 aagatgaagc agtacttata ggagaaagca tagaagtaaa aattgtaggg gtagatggaa
    75961 acaatgtgaa actagctata tcagcgccta acaatataag tatattaaga aaagaaatat
    76021 acgaaaaagt aaagagtgag aatataaaag ctacaaataa aaatataaaa attttaaagt
    76081 cattaaaata ataagcttgg aggaagtaat atatgtatgg agaaaatcct tataattctt
    76141 ataaacaaaa tgctgttttt atggcatcaa aggaacaatt gttacttatg cttgttgatg
    76201 gagcagtaaa atataccaaa atagccaaaa cagctatctt agataaaaat acacaaaaag
    76261 cgcatagaga gcttataaga gttcaggata tatttacaga actaatggtt acattagacc
    76321 aaaatgcagg tcaatgggca aaggatatgt acagagttta tgattttgta agatatgaac
    76381 tttcaagagc taatattaga aaagacattc aaataataga taatgtgttg cctgtaatag
    76441 aacaaattaa agatacttgg catgaagctg ataaaaaaag taaagaagaa agaagtaggt
    76501 acaaataatg gaattaaatt tagctgaatt agataagtta tcaaaagagg aattactatt
    76561 gatgcttgta gatggaacag taaaatatac caatatatcc aaagaagctc ttttaaataa
    76621 cgactatttg aaagcacata atgaacttgt aagagttcaa aatatattta cagaactaat
    76681 gactacatta gaccaagatg caggtcaatg ggcaaaggat atgtataaag tttatgaatt
    76741 tataaaatct gaattagcaa tagctgatga aaataaagat attaaaataa ttgatgatat
    76801 attgccaata gtaaaacaaa ttagagatac atggcatgaa gtttacaatc aactaaaaat
    76861 ataattggat ggagggataa aggtatgtca agtataagtc ctataagagt tacaggtctt
    76921 tcaggaaatt ttgatatgga aggcataatc gaagctagta tgattagaga caaggaaaaa
    76981 gttgataaag caaaacaaga acaacaaatc gttaaatgga agcaagaaat atatagaaat
    77041 gttatacaag aatcaaaaga tctttatgat aaatatctaa gcgtaaattc tcctaatagt
    77101 atagtaagtg aaaaagcata ctcttctaca agaataacca gttctgatga aagtattata
    77161 gtagcaaaag gctcagctgg tgcagaaaaa ataaattatc aatttgcagt ttctcaaatg
    77221 gctgaaccag caaaatttac tattaaatta aattcaagtg aacctattgt tcaacagttt
    77281 cctccaaatg ctagtggagc gagttcttta actataggag atgtaaatat accaatatct
    77341 gaacaagata ctacaagtac tattgtaagt aagataaact ccctttgcgc agataatgat
    77401 ataaaggctt cttatagtga gatgacaggt gaattgatta tttcaagaaa acagactggt
    77461 tcgtcatcag acattaattt aagagtaatt ggaaatgaca atttagctca gcaaattgct
    77521 aatgataatg gtatcacatt tataaatgat gctggtggaa acaaagtggc aaatgtatat
    77581 ggaaagaatc tagaagctga tgtaactgat gaacatggaa gagtaactca tataagtaaa
    77641 gaacaaaatt catttaatat agataatatt gactataatg taaattcaaa aggaactgca
    77701 aagttgactt ctgtcactga tactgaagaa gctgttaaaa atatgcaagc atttgtggat
    77761 gattataata aactgatgga caaggtctat ggtttagtta ctactaaaaa accaaaagat
    77821 tatccgcctc ttacagatgc ccaaaaagaa gatatgacaa ctgaagaaat agaaaaatgg
    77881 gaaaagaaag ctaaagaagg tatacttaga aatgatgatg agttaagagg ttttgttgaa
    77941 gatattcaat ctgcattttt tggagatgga aaaaatatta ttgcattaag aaaactaggt
    78001 atcaatgaaa gtgaaaatta caataaaaaa ggtcaaatat catttaatgc agatactttt
    78061 tcaaaggctc ttatagatga tagtgataag gtatacaaaa cactagcagg ttattcttcg
    78121 aattatgatg ataagggaat gtttgaaaag ctaaaagata ttgtatatga atattctgga
    78181 agttcaactt ctaaacttcc taaaaaagca ggtatagaaa aaactgcttc tgctagtgaa
    78241 aatgtatatt caaaacaaat tgcagagcaa gaaagaaata taagcaggtt agttgaaaaa
    78301 atgaatgata aagagaaaag actttatgct aaatattcag ccttagaatc tttgttgaat
    78361 cagtattctt cccaaatgaa ttatttctca caagcacagg gtaattaatt atggataaat
    78421 taaaagaaaa attaaattta tataaagata tatctttaca aattataaat ttgattgaaa
    78481 aggaagaata tataaagata agtattaagt taggtgaaag acaagagatt ataaatagtg
    78541 taagtgaaat tgatagaaat gattttatac agctttataa tagaatggaa ttaattgaaa
    78601 ttgatagcag gataagagat attttacaag gacaattatt agaagtaaaa aaagaattac
    78661 atgagtataa gcttactaaa caagtgaaca caatgtatta taacttaaat agagaaaaag
    78721 taaatatttt taataaaaaa gtataaagtt atgtaccatc ttgtccgatt atataaatga
    78781 agaattaata aaaaagatta aaagtagaaa tgacaaggat gtcaactata ctaaggaggg
    78841 taaaataatg agagttaata caaatgtaag tgctttgata gcaaataacc aaatgggaag
    78901 aaacgtaaat gcacaaagta agtctatgga gaagctatct tctggtgtta gaattaagag
    78961 agctgctgac gatgctgctg ggcttgctat atctgagaaa atgagagctc aaataaaagg
    79021 tttagaccaa gcaggaagaa acgttcaaga tggtatatct gttgtacaaa cagcagaagg
    79081 tgcattagaa gaaactggta acatactaca aagaatgaga actttatcag tacaatcttc
    79141 aaatgaaact aatactgctg aagaaagaca aaagatagct gatgagttac tacaattaaa
    79201 agatgaagtt gaaagaatat caagctcaat tgagtttaat ggtaagaaat tacttgatgg
    79261 aagttctaca gaaataagat tacaagttgg agcaaacttt ggaacaaatg ttgcaggaac
    79321 atctaacaac aacaatgaaa taaaagttgc tctagtaaat acttcaagta taatgagtaa
    79381 agcaggtata acaagttcta caatagcaag cttaaatgca gatggaactt ctggaacaaa
    79441 tgcagctaaa caaatggtat ctagcttaga tgtagctctt aaagaattaa atacatcaag
    79501 agcaaaatta ggggcacaac aaaatagact agaatcaact caaaacaact taaataatac
    79561 tatagaaaat gttacagcag ctgaatcaag aataagagat acagatgttg cttcagaaat
    79621 ggttaactta tctaaaatga atatattagt tcaagcatca cagtcaatgc ttgctcaagc
    79681 taatcaacaa ccacaaggag ttttacaatt attaggataa aataattttg tatattggat
    79741 atagaagaaa gggtaaggct ttgctttact cctttctttt tttacaaata tacttttgaa
    79801 aggaaaattt atatgttact tagtatagtt atgattgtta aaaatgaaga aaaaatactt
    79861 gaaaaaactt taaaatcatt aaccacatta agaaattcta tagaaagtga acttataata
    79921 gtcgatacag gttctacaga tgatactata aaaatatcta agaagtacac ggaaaaagtg
    79981 tattttcata attggaataa tgatttttct agtatgagaa atatatcaat atcctatgct
    80041 aaaggtgaat ggttacttat attagatgca gatgaaatac taattgattc ttcaactatt
    80101 gtaaaatttt ttaaagatgg tcttgataaa aaatttaatt ctgcttcaat acaattaaaa
    80161 aatctttact catatgataa aaaattatat ggatattgtt cagtgcttag actttttaaa
    80221 aacgttgatt ttagatacca tggtaaagta catgaacaac caatatacaa aaaccctata
    80281 tttaataatg ttgctgattt tgaacattat ggatatttgt ttgaagatga agaaataaga
    80341 ttaaataagg tgaaaagaaa tgaaaaacta ttatttcaag agttaaaaga gaatgataat
    80401 tctccatata caaactatca attagggaaa aattttatta tattaggaaa atatcaggag
    80461 gctttatact atcttgagaa atcttatgaa ttatattcta aactagaatt ggcacctggt
    80521 tacttgataa caagccttgt aaaaacatat ttatatttag gaaaacataa gaagtgtgaa
    80581 agattgtgct taaagtatat taagaaagac atgaataata ttgatatata ttattatatt
    80641 gcacaagcac aagtagattt aggaaagtat gaaaatagta tagattcgta taagagatat
    80701 atttacttgt tagataatta tgaaataagt acacaagcaa atagtttatt ttcagacact
    80761 gatactgtag ggcttagaga tgaggctatt attacactga taaagattta ttataagctt
    80821 gaaaaatatg agtttgtaat ttcagagtat aataacattg aagatgtgga aaagaaaaag
    80881 aatgtgtact ttagcttatt tatgtcacta tataaattga atagatttga agatataaaa
    80941 aattattata aagaagtttc aaattctaaa attgaaaaaa atagttttta tagaaatata
    81001 gaagaagtta taaataatat taaagaggat gaaaaagagt atgtatataa aatcctttgt
    81061 gacattgaag gtaattatgg cattttaaat caaataagga taaataaatg tgtatctata
    81121 gataaatgta aagaaatact caatgaagaa aaggaaataa tttatgcata tattataaaa
    81181 atagcttttg aagagaagat tgatttacta gatatttttt atgaaatgga atatgtatgg
    81241 atagagaaat atctaaaata tcttttagca ttagaaagaa gttttaattt agtactatat
    81301 aagtacataa ttagtcgtcc aaatacatca gatatggaaa agataagagt atataaagct
    81361 atatctaaag tagttttaga aagtataagc ttaagtgatg aaaaatataa ggagattttt
    81421 tatctttata taatgtattc ttataagtac ataagataca tatatagcaa tttaagtgat
    81481 tttgaattaa taaaatttgt ttgtaatgat ttagataagt tcactataga atttaagcat
    81541 ctacttgata ttaaaaataa agtaaataat gctaatgaaa aattagagta tatacatagt
    81601 atgaggaaat tactaaatga gtatcctttt tataataaaa taataaaaat acttataggt
    81661 gaattagaag aaaatataaa agaaagtgaa gaatttaagg atttaaaaga tagttttatt
    81721 attagtatag aaaatatgat tgaaactggc aaaataaatg atgcgaaatt attggtagat
    81781 gactattcaa aaacatttgt ggatgatata aagattttaa atataaaggg aattttatac
    81841 atgtttgaaa ataagcttga taaagctgat tttatgttaa aaaaggcatt atcattag
//
LOCUS       DAEPHU010000007        75068 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 01A10CD0081
            SAMN05941466-rid12468953.denovo.007, whole genome shotgun sequence.
ACCESSION   DAEPHU010000007 DAEPHU010000000
VERSION     DAEPHU010000007.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941466
            Sequence Read Archive: SRR6291087
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 75068)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 75068)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068158.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 22:43:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,892
            CDSs (total)                      :: 3,805
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 87
            rRNAs                             :: 8, 1, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 55
            CDSs (without protein)            :: 55
            Pseudo Genes (ambiguous residues) :: 0 of 55
            Pseudo Genes (frameshifted)       :: 21 of 55
            Pseudo Genes (incomplete)         :: 28 of 55
            Pseudo Genes (internal stop)      :: 16 of 55
            Pseudo Genes (multiple problems)  :: 8 of 55
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..75068
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941466-rid12468953.denovo.007"
                     /strain="01A10CD0081"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            complement(415..1506)
                     /locus_tag="KR231_000504"
     CDS             complement(415..1506)
                     /locus_tag="KR231_000504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rpn family recombination-promoting
                     nuclease/putative transposase"
                     /protein_id="HBH0002920.1"
                     /translation="MIEKVEEKSKIIKTSKEYKRTIIEEKDKEWTKKLNDILSRSSFS
                     NDELDKIKALIPKEILTNENVGEVVTEDGYAKPEYDEVFKSLFTLNNEYDLLVNFIND
                     ILKDAPYANRNIKPFTQIKRIIRVETDPTINYIGEKRPKLDILAEDEENNHINIEMQR
                     AFENDYLERAEYYLSRVHGRKLEEGKEYKEIGKTIGIHILNHVKYNHIEDYVNCLRLT
                     MDGHPDIYSSKTALYFIELPKIHKSDYIVNRIMLWGKLISNPSNLDVRVIAKNDSIIK
                     KALDRLKELGSNEEYLLNLKRGAYIMNKSRNFKEEIERETAIRVAKEKDYKIIIMLKK
                     NGFKLDDILNKFNDFDLSEDEIKEVYENN"
     gene            complement(2274..4193)
                     /gene="thrS"
                     /locus_tag="KR231_000505"
     CDS             complement(2274..4193)
                     /gene="thrS"
                     /locus_tag="KR231_000505"
                     /EC_number="6.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009904969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine--tRNA ligase"
                     /protein_id="HBH0002921.1"
                     /translation="MIKVALKDGSIKEFENAISVMDVAKSISEGLARNVVAASVNGEV
                     VGLDHIIDTDCDLNLFKFEDKEGKEVFRHTSAHILAQAIKRLYPEAKLAIGPSIENGF
                     YYDIDLDHRLVPEDLEKIEAEMKKIAKEDLKIERFELPRNEALELMKEQGEDYKVELI
                     SDLPESEIISFYKQGDFTDLCRGPHLPSTKKVKAVKLQSVAGAYWRGDENNKMLQRIY
                     GTSFEKNKDLEEYLHLLEEAKKRDHRKLGKELGLFMIPEEGPGFPMFLPKGMELKNEL
                     LKFWREIHRKAGYIEIESPIILNRKLWETSGHWYHYKENMYTVKIDDEDYAIKPMNCP
                     GGLIYYNSQLHSYRDFPMRVAELGRVHRHELSGALQGLMRVRAFTQDDSHIFMLPEQI
                     KDEIKGVANLIDGIYKTFGFEYNLELSTRPENSMGSDEEWEAAENGLREALEELGLPY
                     TINEGDGAFYGPKIDFHLKDCLGRTWQCGTIQLDMQLPRQFDNTYIGQDGEKHRPVMI
                     HRVAFGSIERFIGILIEHYAGKFPVWLSPTQVKILPISDKFMDYANEVKKELFDKGIR
                     VELDDRAEKIGFKIREAQLEKVPYMLIVGEKEVADNNVSVRSRDKGEIGSIKLDEFIA
                     SISKEIESRESIIQD"
     misc_binding    complement(4257..4494)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(4953..5555)
                     /locus_tag="KR231_000506"
     CDS             complement(4953..5555)
                     /locus_tag="KR231_000506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF445 family protein"
                     /protein_id="HBH0002922.1"
                     /translation="MDNLIRILILAVIGGFIGYVTNVVAIRLIFRPIEPIKIPILNIE
                     IVGLIPKRRAEIAANVGEIIQEEFLSMDEILANIITDEDKEEVVRYIKARVKIIIHEK
                     VSFIPSGIKNMIQDYLGEIIESEVKQSIDELSKNIINKANERIDIQKMVEDKINELDL
                     YELEEIIIRIAKKELKHIEFLGLVLGFLIGIAQGLITMFI"
     gene            complement(5735..6553)
                     /locus_tag="KR231_000507"
     CDS             complement(5735..6553)
                     /locus_tag="KR231_000507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative sporulation protein YtxC"
                     /protein_id="HBH0002923.1"
                     /translation="MVEKDNISSMKFLRNNNVNDRLIYTNDIVEVVIDSAKQEVLNKK
                     ILNGTKAEQRALNIDEISTEITSMIISIMKEKLLKEYILKCYGRTYPEDKNNIYIYSL
                     NIFAKKEIFMRETVFTRVRNYIEENDFINVEGFIRFRMREFMKYISAIGDIAVEEYLI
                     KKDQDEFIRVLKYFIDTQEEKIDLLKVHIMEDNTFVLYDKNGNKIDSIDDEEIINMVI
                     RENLNYEDFLISTLLTLCPKKIEILDLLNNNCSKEIIDTVEAIFENKVSIIMEN"
     gene            complement(6556..7317)
                     /locus_tag="KR231_000508"
     CDS             complement(6556..7317)
                     /locus_tag="KR231_000508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417991.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0002924.1"
                     /translation="MEFTREPFILDDDLCLALVDKRISYLMENELKLRNIEIIKTIEC
                     KELYESIKYHPDICICNLGKGDIIVAPNVYNQYKELLSRYKFNIIKGEANLLNRYPYD
                     IPYNIAIVGDYAIHNFKYTDKAILDYIENNKLKKINIEQGYSKCSICIVDRTSIITSD
                     KGIWKSMKNTEIECLLIEKGHINLFEMNYGFIGGCTGLISKDKLAFCGDVKKHPDYER
                     IKSFVESKNKEIVTLSCENLLDIGSIVPLMTRKER"
     gene            complement(7807..8919)
                     /locus_tag="KR231_000509"
     CDS             complement(7807..8919)
                     /locus_tag="KR231_000509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BMP family ABC transporter substrate-binding
                     protein"
                     /protein_id="HBH0002925.1"
                     /translation="MKIKRILMACFVVVFTIFILAICNFDFGFDKVNKNNSNIDSAKS
                     KQSESKSLPTSAEKDKSNSKSKNKEDDTEDDSYVRKTIGVLLDTENLNNESYNNNVLS
                     ALKRADEDFDVRIKLEKPKTSKSFKESIEKLHKYEPDLIIAVGARFAEPIKEAATEYP
                     KQQFAIVDYTYKVQPANVISVSFQDNVTGYLAGLIAGKMTDTGKVGFIGGVEGSSRDK
                     YESGFRKGLKTSNKDAELLVKYSNIFENPESARTIAKEMRDSDRDVVFSATEDDSKRA
                     IQVARENGGKVIAINKDQYDMAPDNVISSIIKDVEQPVYELIKNVAKDGFKGSKVMEF
                     KIKDGELGLTSKSSRNIPPDVLEYIKKEYNKVKDTY"
     gene            complement(9045..10049)
                     /locus_tag="KR231_000510"
     CDS             complement(9045..10049)
                     /locus_tag="KR231_000510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BMP family ABC transporter substrate-binding
                     protein"
                     /protein_id="HBH0002926.1"
                     /translation="MRFKRILILMLTVAMIAGMLVGCANNPSNNPSSSKDNKSDISDK
                     SNSKKSVSMILDIEGTNNEAMNNSALLALNNAQKKLNIDTNKVESDDSSTFSNSIDIL
                     CNDNYDLIIAVGARFAKPLEMVAKKYPKQQFAIIDYEYDKQPSNITSISYEDNKSGYL
                     AGLIAGKMTESDKVGFIGGTKSSSRDKFESGFREGVKFSNSSIKDISVEYADVFKDSK
                     SVESIAKKMMDNGVDIIFSTTEDDSKAVIDAVRAKNKKVIATNKDQHELAPENVISSI
                     VKDFENPTYNLIQSFVKGNYKGGKVIENTVKSGSTGLAQNSSQNIPPDVLEYVNKNNK
                     "
     gene            complement(10354..11202)
                     /locus_tag="KR231_000511"
     CDS             complement(10354..11202)
                     /locus_tag="KR231_000511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HBH0002927.1"
                     /translation="MKNLKIICDSLSDVPKDLLDKYDIDIVSLTVILEEREYKDRIDI
                     SGDEFYKKLREENVYPKTSQATYAQFKEIFEKYTNEDREILYIAGSATATGTYQSAVM
                     AKNDVDGKIYTYDSNLLCMGTGLLVIKAGELASEGKSVAEILPVLDELKEKAFVIFSV
                     DTLEYLQKGGRISSTKAAIGSILNIKPILEIRDGLVSQISQVRGKKNVISKMMELIKS
                     NCGDDLSDQIVYIGYSDDFKEKEQLSKVMQDELRPKEIRFFQIGVCIGAHAGPGVTGI
                     ICLKNK"
     gene            complement(11238..11708)
                     /gene="trmL"
                     /locus_tag="KR231_000512"
     CDS             complement(11238..11708)
                     /gene="trmL"
                     /locus_tag="KR231_000512"
                     /EC_number="2.1.1.207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (uridine(34)/cytosine(34)/5-
                     carboxymethylaminomethyluridine(34)-2'-O)-
                     methyltransferase TrmL"
                     /protein_id="HBH0002928.1"
                     /translation="MSLNIVLVEPEIPQNTGNIIRTCAATGSTLHLVKPLGFSLDDKH
                     LKRCGLDYWDIADIQYYDSFEELQEKYPNSKYFFSTTKAKQSHSDVKYEENCFIVFGK
                     ETKGLPEPLLKANMDTCIRVPMLDVEKARSLNLSNSVAIVVYEALRQIGYPNMR"
     gene            complement(11902..13119)
                     /gene="nth"
                     /locus_tag="KR231_000513"
     CDS             complement(11902..13119)
                     /gene="nth"
                     /locus_tag="KR231_000513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease III"
                     /protein_id="HBH0002929.1"
                     /translation="MKNVNLKEINEKDVILEEEINKKGMDKKNIIEKEEINKKGIDKK
                     DIIEKEEINKKGIDKKDIIEKKEINKKGIDKKDIIEKKEINKKEMDKKDIIEKEEINK
                     KGMNKKDIIEKEEINEKEIDKMIGKKDEIIDEKDIENFMDIEEDKKSIKVSKKSTKKG
                     ETEKKTKKSSSNKATQKTSKETKSKFKIKNESANEKDVNKILDELEKLYPDAKCELNY
                     GTAFELLIATILSAQCTDVRVNKVTSELFKKYNTARDFANLSIEEISKEIKSCGIYKS
                     KSQKIKDTSEQLCELYDGEVPDSLEKLIKLPGVGRKTAGVVLSNAFNHPAIAVDTHVF
                     RVSNRIGIVDEPNPQKTEFALMEAIPKERWSHSHHVLIFHGRRMCKARNPECASCPIK
                     EDCNYYKELNETK"
     gene            complement(13317..15554)
                     /locus_tag="KR231_000514"
     CDS             complement(13317..15554)
                     /locus_tag="KR231_000514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HBH0002930.1"
                     /translation="MKYNNTSEINPLDYILGQERAVEAMELGLKINNPAYNIYIAGEP
                     GTGKSTYALKVLNEYASKKNTHKDWCYIYNFENPREPIIVELEKGFGRELKKDMEKLI
                     ESLLEDFKNAFESENFEIEKNKLLDEYEIEKDMLLKQIKKYGEEKGFKLKQSKMGIVF
                     IPLKEEEDESDESDEEFYKAKRELENMAIQVVYKIRNLEEIAEKAVLELEEEIAKLVV
                     EPHIKRLCEKYENYDKIQTYLENIKKDIIEYMYLFYLDEEELKDKYDKEHFIKYKINL
                     FVDNGSSKNKESAPVVVEINPSPANLFGKAEYDYANGNIKTDFTKLLSGAFHRANGGY
                     LVLYADQLLKYTMSWEILKKTLQTKKVILETQTAIKPENMPLDVKLVLIGSHYIYDIL
                     YRYDEDFEKYFKVFVDFDSEMDKNEDNEEGIARFIAYQCDKNNLRHFTKSAVEEVIKF
                     STRLSGDLEKLSTKFNKIMEVVIEGSAYAEFRNSEYTKQCDVKKAISEKRKRINRVET
                     HMDESIENGFTLIETEGRKVGVINGLSVLSTGEYSFGRASRITATTSPGSKGIVNIER
                     EVNMSGSIHNKGVLILGGYLSENFAQDLLLSLNAYVCFEQNYGGIDGDSASSAELYVL
                     LSSLSGVSIKQNIAVTGSINQKGDIQVVGGISEKIEGFYSICKTKGLNGEQGVIIPRK
                     NQRNLVLSDEVNDAVRDGKFKIYTVERVEEAIEILTDVKFEEIKKLVKEKLISFSKIQ
                     TVSKE"
     gene            complement(15660..16574)
                     /gene="queG"
                     /locus_tag="KR231_000515"
     CDS             complement(15660..16574)
                     /gene="queG"
                     /locus_tag="KR231_000515"
                     /EC_number="1.17.99.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA epoxyqueuosine(34) reductase QueG"
                     /protein_id="HBH0002931.1"
                     /translation="MDNKELKAFCNLIGLNCVGVAGVDKYDNLEKILKNRQQKGYLTG
                     MEEPIIESRINPRHIMKDANSIIVCAFPYHINRQEKNKNSNLSKYCHGKDYHIVVKDF
                     LQQICDYISKTVTDFKYKLFADNGPLVDRYLAYLSGIGYFGINNNIITDEYGSYVFIG
                     YIVNNYKFEEDKPLEKSCFKCGKCVKYCPGNAILGNYDMNPKKCLSYITQKKGDLSEK
                     EKVVLKNGKKVFGCDICQEVCPHNVEIPTTHILEFKENIIDYLDYDEIQNISNKEFKR
                     RYGDRAFSWRGRNIIKRNMEIILDKYDD"
     gene            17415..17819
                     /locus_tag="KR231_000516"
     CDS             17415..17819
                     /locus_tag="KR231_000516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RusA family crossover junction
                     endodeoxyribonuclease"
                     /protein_id="HBH0002932.1"
                     /translation="MIKITIPGRPISKSNFKLHNINGQAWMPSKGKYSKYLAYENMIA
                     GFINQQYQGETVEENLITVLKLFFPNKRMGDLHNYPKSICDGIEKSGIIKNDKQLKPV
                     LLFDFIDKDNPRVEIELYPVSKYDISYNIFEK"
     gene            complement(18076..19071)
                     /locus_tag="KR231_000517"
     CDS             complement(18076..19071)
                     /locus_tag="KR231_000517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HBH0002933.1"
                     /translation="MRNLGNTNMKIKRVGFGGIPIQRITQDDTNLVINELEKQGINFI
                     DSARGYTISEEAIGIAIEGKRDKFFLATKSMSRDYDSMKRDVEISLNNFKTDFIDLYQ
                     FHNVKEEEYDNLFKDKMAYSALLEAKEQGKIKHIGITSHNLNTIEKAIEDGKFDTIQF
                     PYNIVEGQADEVFKKAHEKGIGIIVMKPLAGGALDNATLAIKYILSKDYIDVVIPGME
                     SVEQVRQNVAVLENLVLDEKDNKEIEEIRNSLGKKFCRRCEYCMPCAVGINIPLSFLC
                     EGYYTRYGLKEWAKEKYEVMDVKPTECIDCGLCESRCPYELPIREMLKTVVEKLG"
     gene            complement(19355..20191)
                     /locus_tag="KR231_000518"
     CDS             complement(19355..20191)
                     /locus_tag="KR231_000518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribonuclease IV"
                     /protein_id="HBH0002934.1"
                     /translation="MIKLGTHLSIAKGFANAAETAVYIGANTFQFFSRNPRGGNAKEF
                     DEKDIIKFQEIRKENNFAPLLAHAPYTMNLGGTKDDVYEFATRVIDEDIRRMDSLGIE
                     YMCFHPGSHVGGGVDFGIDRIVKGLNNAIKGDENITILLETMSGKGTEIGFKFEQLKS
                     IIDKIEHKEKIGVCLDTCHIFSAGYDIVNDLDGVLEEFDKVIGIERLKTVHLNDSMMP
                     FGDKKDRHAPIGEGKIGLKALIDFMEHPSLKHLPFFLETPFDDEGHKKELKMIKEILS
                     SK"
     gene            complement(20679..21242)
                     /locus_tag="KR231_000519"
     CDS             complement(20679..21242)
                     /locus_tag="KR231_000519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBH0002935.1"
                     /translation="MKEVLVLRDLECIKAIAHPRRIDILKAFDKSPLSAKQLSQLLEE
                     PHAKINYHIKMLYKVGILELVEEKIKSGIVEKYYYPSAKNVVIGNRILNFSLDNGEEK
                     EELYISKFENMSEVFYKAAEEDVLENENIVDYHDISLTHDELVELSDTMKSKIDEILN
                     KRQHNVEGSKYDIAMVIVPTLEEECPS"
     gene            complement(21340..22269)
                     /gene="glsA"
                     /locus_tag="KR231_000520"
     CDS             complement(21340..22269)
                     /gene="glsA"
                     /locus_tag="KR231_000520"
                     /EC_number="3.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutaminase A"
                     /protein_id="HBH0002936.1"
                     /translation="MNTLDETLLKEIISSNKKYTNYGQVASYIPELKNARRNDLGICI
                     IDSENNLYSAGNCSTKFTIQSISKPIVLAMALMDNDWEDVFSNVGMEPSGDPFNSIMK
                     LEINDTKKPCNPMINAGAIVTTSLINGSCLEEKEERMLSFFRKLAKNDNIGINYDVYK
                     SEKMTGDRNRAMAYLLKSDGFIRGNVEDVLDLYFKQCSIEIDSVDLARIGINLANYGV
                     DIENGEHLMSEMVSRIVKTFMMTCGMYDASGEFAIKVGIPAKSGVGGGIMASVPGRMG
                     IGVYGPALDKKGNSVAGVKVLEELSNKLKLNIF"
     gene            complement(22826..24493)
                     /locus_tag="KR231_000521"
     CDS             complement(22826..24493)
                     /locus_tag="KR231_000521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside kinase"
                     /protein_id="HBH0002937.1"
                     /translation="MKKINLKIEGKDKEYSLEENSPGIRLGDIAKEFCDEHKGYITLA
                     VVDNKLKELNCRVKKDCEINFLDTTNEDGERVYFRVMSFIFVMACREIFWDSRVTIEH
                     SLSDGLYCEVHIDRKLKEADVENIKNKMKEIVNNDYVIEKIEVTRNEAISIFENNEMY
                     EKAELLKYKEYDSAKVYKCRNYIDHFYGYMLPSTGYIKSFDIKLYNGGVIILGPSEED
                     KTLPMKFVPQPKLSSVYYEAEEWSRLMGIDKVVSLNKIIENNEYGDIIRTFEALHEKK
                     LSQIADMIKDGNKRVVLIAAPSSSGKTSFAHRLSIHLRVNNLNPISISLDDYFIDRKH
                     TPLDEYGNYDFESIYAIDLEKFNLDLKKLLAGEEIDDIRFNFKEGKREYTGKKIKIDS
                     NQPIILEGIHGLNPILTSSIPDEDKFKIYISALTQINLDDHNRIPTADLRMIRRIVRD
                     YNFRGYSADNTILQWASVRRGEKKNIFPYQEEADAIFNSACVYELAVLKRFAKPLLEE
                     IKEDNPAHIEATRLLKFLQYFVELDDTSDIPGISILREFIGGSKIVD"
     gene            complement(24567..25322)
                     /locus_tag="KR231_000522"
     CDS             complement(24567..25322)
                     /locus_tag="KR231_000522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIM barrel protein"
                     /protein_id="HBH0002938.1"
                     /translation="MAVGIASLLFNIEEALNICESIKQITHLEIGIDNISECSELCKY
                     KERISKLGLSIGIHLPMELNTCENIEYIRNSWINFIEKIEFELKGFDLRYFNLHLGYV
                     MTNRVRKNRDKYLGNSVDFLDKLNTNSYVCIENTYSKGGDFSNIGNISYDFEYIFKRI
                     KNSKICFCYDTGHCLIDEDAYVKNLKDKIRLIHLSDNDGINDTHVGIGRGILSEEGIK
                     EVLTLDAEYLVLEINYEDIEDTISKLNNIVGEG"
     gene            complement(25332..25868)
                     /gene="lepB"
                     /locus_tag="KR231_000523"
     CDS             complement(25332..25868)
                     /gene="lepB"
                     /locus_tag="KR231_000523"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HBH0002939.1"
                     /translation="MNETIKEEIVEWIKIIITALFFAFIITRFIKPTLVNGESMYPTL
                     KSHDYLVANRMTYKLSEPKCGDIMIFKTDLLQENGRKKELVKRVIGVPGDHLKIKDSK
                     VYINGKLLNEVSYIHDNYTEGDIDMVIPKGKVFAMGDNREVSLDSRYKEVGLVDEENI
                     KGKVILRVFPFTDIGIFE"
     gene            complement(26034..26570)
                     /gene="lepB"
                     /locus_tag="KR231_000524"
     CDS             complement(26034..26570)
                     /gene="lepB"
                     /locus_tag="KR231_000524"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HBH0002940.1"
                     /translation="MGEAVKKEVVEWIKVIVIALVLAFAITRFIVPTIVKGESMYPTL
                     VERDYLIVNRIAYKVGEPKYKDIIVFKTDLTEENGKKKDLVKRVIGVPGDHVKIQDSK
                     VYVNDKLLDETSYIHNNRTDGDIDIVVPEGKLFAMGDNREKSLDSRYDEVGLVDEHTI
                     LGKVLVRLYPFSKIGTID"
     gene            complement(26670..27980)
                     /locus_tag="KR231_000525"
     CDS             complement(26670..27980)
                     /locus_tag="KR231_000525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RsmB/NOP family class I SAM-dependent RNA
                     methyltransferase"
                     /protein_id="HBH0002941.1"
                     /translation="MTELPNEFLEDIEEILKDEYDDFIKSYEESKTTGLRINTLKIDK
                     KKLFDLELFDLNQIPWAEEGFYYDDKIDRPGRNPLHEAGAYYLQEPSAMSVIPKADIK
                     EGEKVLDMCAAPGGKSTYILSKLNDTGLLVSNEINASRIKALGENLERFGARNCIITN
                     TDSNSLRKTFNGYFDKVIIDAPCSGQGMFRKDEVAISDWSYAKVVECQSIQKEIIRDG
                     YKMLKKDGILIYSTCTFSREENEHVINEFISEYPHAELIEMERLWPHKIKGEGHFVAK
                     IKKLEEEECNVKELKIKNLDKEIKDYREFEKKFLKVDFYSNKKNKFYLRGENLYLLPE
                     IYPDTKKLKVLRYGLHLGVLKKNRFEPSHALSHYLKVEDVKNVENFSVQSESILKYLK
                     GDVVNSNDSRGWVLVSVEGIPLGWGKESSGVIKNHYPKGLRKVF"
     gene            complement(28059..28775)
                     /locus_tag="KR231_000526"
     CDS             complement(28059..28775)
                     /locus_tag="KR231_000526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PrsW family intramembrane metalloprotease"
                     /protein_id="HBH0002942.1"
                     /translation="MKLDLFLLAIVPILIGMFWIRSKDRYCREPLIHLIKFFLIGAFL
                     SVIIILLENLLMKFNVFEGYSELIYVSFVVAGLVEEGVKALILIPALIKEKHFTEKLD
                     GIIYSVFLALGFATIENMVYIFSESRNLALQVGINRAVISIPAHVMFAITMGYYISKY
                     KFEGNKNKRREYLFMAVLIPILLHGVFDFILMIEYRWAIILLIVYVIILWKINLDKLE
                     KYMNHSKKVFFGNLRKKKKK"
     gene            29020..30291
                     /gene="sleC"
                     /locus_tag="KR231_000527"
     CDS             29020..30291
                     /gene="sleC"
                     /locus_tag="KR231_000527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="spore cortex-lytic protein SleC"
                     /protein_id="HBH0002943.1"
                     /translation="MQDGFLTVSIIDATNNRPIQNAVVNIYSMSNGSQSSSTLYQNLR
                     SNESGQVTGLVLPAPDVDYSLQPSDVRPYSQYIVEAIADGYETVVIEGTQLLATIEAR
                     QGVPMSPRTRSKRSFSRQSELIFDIGEHTLYGTYPPKIPESNLKPLPPPTGFVVLDNP
                     VVPEFIVVHDGLPEDSSAPNYWIPFKEYIKNIASSEIYSTWPEQTIYANVIAIISFTL
                     NRVFTEWYRNKGYNFTITSTTAYDHKFINNRNLFEPINVVVDAIFNTFIKRPPTSRQP
                     LLAQYCDGQKSQCPDQMTQWGSKDLGDQGYDYESILRYFYGDEIVFERAPIVSGVPVS
                     FPGTTLQVGSSGQYVRTIQNQLNAISNSYPAVPKVIEDGIYGTDTENAVKIFQGIFGL
                     PQSGVVDFKTWYEISRVYVATTRIASLNPLI"
     gene            complement(30799..31455)
                     /locus_tag="KR231_000528"
     CDS             complement(30799..31455)
                     /locus_tag="KR231_000528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0002944.1"
                     /translation="MKKGDFIWSGVLICIIAVLAIPSSREVFMEATGAHPYIGGFLKF
                     AVLATMGDLLGARILYKDWKIPVGVFYRAIVWGIIGVVTTYGMSIYSSGVGQAQVDGM
                     LPFEGIAFANALFKSATMNILMSPTVFLFHKVMDCFIDKKYEVGKGIKVKLKDVVNIV
                     DWNAYLGFSVLKTIPFFWIPCHTIVFLFPAEYRVIASAFASIALGLILALANKSKVAV
                     "
     gene            complement(32727..33137)
                     /locus_tag="KR231_000529"
     CDS             complement(32727..33137)
                     /locus_tag="KR231_000529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0002945.1"
                     /translation="MKIKKSLISAMMVSAMVLGGTGAVFANGNDSSNIALPKLESLIK
                     SGITDPTELEKYGVEHYTYEEYAKHIQELKDYAKDPNAVKDVSQKDLEETIKKMEQEL
                     EKIKTEGLKIMKPITIENEDGSQISIAYNYAAID"
     gene            complement(33353..34735)
                     /locus_tag="KR231_000530"
     CDS             complement(33353..34735)
                     /locus_tag="KR231_000530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M56 family metallopeptidase"
                     /protein_id="HBH0002946.1"
                     /translation="MFIKLLEMSFTSGVLLLIVIFIRACLFKKLPKKVFVLLWLIVLF
                     KLLIPVSLNSGFSIYSIIESTFDVELGNTSTENYTLKKASDSTGKNNSDEFEIMSNIE
                     NIMMLEMLGILSFIVTIMFSILLCFRYFKIINLFKTSIHIKNHEFIKKWMCKNSRFRR
                     FIVCISEFTRTPLTSGILKPRIILPKQMNYANNQTLDFVLTHEMVHINSFDNLLKLFM
                     LVALVVHWFNPLVWVMFFLLNKDIEFSCDEKVMSILGEEYRADYATTLISLAEENNPF
                     SMTICSGFGKTKIEKRIVNIMKFKKSTYVTFLVSTVLVCGTGLVFATENKEINEVESF
                     GLTKNEQSDKIGFSISSKSTDLYSPKVESDILVSKAKSDGETHFSTAKVSVIEFREHE
                     ESSMSKVTNSENSEETYVNKSSNGKDVLYTDSGEVSIEQSGYNDNRFVISRKGNLLAV
                     NKEQYRTWIE"
     gene            complement(34746..35105)
                     /locus_tag="KR231_000531"
     CDS             complement(34746..35105)
                     /locus_tag="KR231_000531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
                     /protein_id="HBH0002947.1"
                     /translation="MEIKLFDSELKVMEVLWERGESKAGELVKILKEETGWNRNTTYT
                     VIKKLVSKGAIERIEPNFVCKALISKEEVQKQETETLINKMFGGSSEKFLSAFINKEN
                     LSSDEITKLKQIVEKLK"
     gene            complement(35310..36089)
                     /locus_tag="KR231_000532"
     CDS             complement(35310..36089)
                     /locus_tag="KR231_000532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF975 family protein"
                     /protein_id="HBH0002948.1"
                     /translation="MVSRQELKRVSKAQLSGNWGICAISMAVYIALIVLISIVGLPFE
                     PLTTIVVAVIAFCVSAGFTCMFLKITKDEKVKIGDIFVSGRIYLRSFGFYLFESIIVY
                     IYSFIITIIGAFLSFGVLLTSGAIEYLSSDNVGIGTVISTGITLVLIILVLMLPVYIL
                     LLYVSQATFLICEDKDNMGVFKSMGASLDMMKGNVLKLFVLNFSFIGWYILSIATLGI
                     GLLWLIPYVGVTNCNFYRQLVKENPDVEDILLDKEKSYTMY"
     gene            complement(36550..37161)
                     /locus_tag="KR231_000533"
     CDS             complement(36550..37161)
                     /locus_tag="KR231_000533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein"
                     /protein_id="HBH0002949.1"
                     /translation="MKMVKKLILSTIMALVLVLTIGCSNAEEKVKSNFEANLAALEMY
                     KYDEKGISDALTEAEYKQIQTYNSKDKVSMIAQLTPLYGKENAEKIYETIVKLIQGVE
                     KTVTVESSSKDKITLKVVSKALDTSKVMSEANTLVKSYVTDEKNYDKKEKEVQDDMTK
                     MIIDLYNKKPTKEVTTMITYTKKDGKWQPPSNIQKLCEGIYTI"
     gene            complement(37253..38242)
                     /locus_tag="KR231_000534"
     CDS             complement(37253..38242)
                     /locus_tag="KR231_000534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine cyclodeaminase family protein"
                     /protein_id="HBH0002950.1"
                     /translation="MLLLKKDDIKKVFTMRDAIEADKEAFRIYCEGKSVNPLRTNISV
                     PSQDASMLFMPGYIEELGCGGIKIVSVFPKNAQKGKPVIPATVLLLDGETGEVSAVLD
                     GTYVTQIRTGAASGAAIDVLAKKDSKIGALIGLGGQGEPQLEAMIEARNLDEVRVFSR
                     NKESREKFAEEMNLKLSKYNTKIVAVESSDEAINNADVIVLATPSKQPVLNGNLVKKG
                     ALISAVGSYMPDMQELCPNCLTRASKIFFESTDAVLSESGDILIPLKEGKISKDDFSG
                     DLGNVINGTIPGREDDDEIIVFKTVGIGVQDVVTAKRIYDKAKENGIGIDWKW"
     gene            complement(38309..39172)
                     /locus_tag="KR231_000535"
     CDS             complement(38309..39172)
                     /locus_tag="KR231_000535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3298 and DUF4163 domain-containing protein"
                     /protein_id="HBH0002951.1"
                     /translation="MKFFKVDTKAKVLRYVFVLTLTIMAVLAIKHDYKYNNLRKDASI
                     NLNSNKEAVTVMSNQSLPKGNTNSKQTLSVSTIGSKTIVKNDEYLESTINMPVITNSN
                     KIVERSTNDKIKNDIFEFYNKSYKEAKQYLKDNPDEKNKFVANVDFELKKNTDSALSI
                     KVRYYTYSGGAHGFYQDIAYNVDMRTGKFLELMDLFKDNTKYKEVIDEEIKRQIAELE
                     KKDEENIGIYNFKGIKENQNFYLQDENLVVYFDLYDITPYAAGIPEFSINKALISSML
                     KPEYVDLFDLK"
     gene            complement(39278..39874)
                     /locus_tag="KR231_000536"
     CDS             complement(39278..39874)
                     /locus_tag="KR231_000536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chemotaxis protein CheB"
                     /protein_id="HBH0002952.1"
                     /translation="MERFNNMVIAIGASVGGTEAILEIIKDLPKSTPGIVVVQHMPAI
                     FTYMYAQRLDKQCIMNVREAKNNDRVEQGNVLIAPGGYQMKLCTDKQGYYVTCEKGER
                     ISGHCPSVDVLFDSVAEVAGKNSIGIILTGMGYDGANGLLKMKENGSFTIGQDENSCI
                     VYGMPMVAFDRGSVMLQLPLGEISNCLIRHINILKQKD"
     gene            complement(39914..40717)
                     /locus_tag="KR231_000537"
     CDS             complement(39914..40717)
                     /locus_tag="KR231_000537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein-glutamate O-methyltransferase CheR"
                     /protein_id="HBH0002953.1"
                     /translation="MIKLTDEEFIVLVNYVKKEYGIDLSKKRALIEGRLYNTMIEKKL
                     SSFSQYMNLLFKDKTGNEAINLINRLSTNHTFFMREPQHFEFIQNSILPFWEENNKIR
                     NINIWSAGCSSGEEAYSIAMTLDDYFGYNKELWNIKIIATDISTNSLEKAKRGIYIES
                     NVNNVPELWKKKYFIDNKDGTFKICDKIRKSVIFKPFNLMNDFSYQHFDLIFCRNVMI
                     YFDLKTREELINKFYNATKKDSFLFVGHAEVINRSSTKYKYVKPAIYKR"
     gene            complement(40753..41193)
                     /locus_tag="KR231_000538"
     CDS             complement(40753..41193)
                     /locus_tag="KR231_000538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chemotaxis protein CheW"
                     /protein_id="HBH0002954.1"
                     /translation="MAKDEIIKQVLTFYVNDVIYGIELENVIETIRFQSITYVPCLPT
                     YISGVINLRGRIIPVINMHIKYNLPKADYNERTCIIITKVDEYQVGIIVDKVVDVIHI
                     ENLNLLETTNSNNTNINKDIKEIAKVEDNSILILDIRKFLINSI"
     gene            complement(41206..43308)
                     /locus_tag="KR231_000539"
     CDS             complement(41206..43308)
                     /locus_tag="KR231_000539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chemotaxis protein CheA"
                     /protein_id="HBH0002955.1"
                     /translation="MRQMLDMFIFETSLLLEQLDEIMIQIEKEKVFTHNNINETFRIM
                     HTIKGSASMMGLDNISALAHSVEDLFYAIREGKIEVLDNDLLFDLVFQSLDFIRRDID
                     ELQSRGCISSDYSNFIEGIEEYVSTLELSSSMKSKDNANLESKDEKEVIDSNFEYKED
                     SDVVKIIFEQGCMMENVRAFMLVFELRDYCEFIDFYPKDVETNAESTEYIKSYGFYIQ
                     FVAKEDKAIVYKTIEDNLYVKEYINISKKEIEMKNTSNNDAVENKLKDNNKVSKSYQN
                     NYTEDEIQEDVLNEKTDMEKDSLSEENEHLPISKQSIMSVNLEKLDLLQNIVGEIVIM
                     ESMVVNSVNSTGVDIDNFNKATRQLHKLTDELQDIVMSMRMIQIAGVFQKMHRIVRDM
                     NKKLDKNVELITIGAETEVDKSVIDNLAEPFMHLIRNAMDHAIEPIEERIAKGKEEVG
                     KIVLSAENLGGEAVISISDDGRGIMRDKILAKAKEQGLLKHQSNEYTDDEVNSLIMTP
                     GFSTKESITEFSGRGVGMDIVRKSIEKVGGSIEVKSKQDEGTTFTIKIPLTLSIVEGM
                     KFKVGDSLFTLPISSIRRTFKLTDLNQIITEGNKTELITIYGACIPIIRLHKIYNIQT
                     KVTNLMNGNMIIIENEHKAVCIFVDEIIGNQQVVVKPFPVYFNRFNIKNKGLSGCTIL
                     GDGSISLIIDADSIIEIY"
     gene            complement(43569..45272)
                     /locus_tag="KR231_000540"
     CDS             complement(43569..45272)
                     /locus_tag="KR231_000540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing protein"
                     /protein_id="HBH0002956.1"
                     /translation="MKREVKLSKLAIVLLIIIVLAVLAGIFSSISSYKAFEKVEKSIN
                     DMNNLRTQSQYIKDTTREISDVLRRYVFTGEKKNKDIYEKELYGKTRESALNKLEKIG
                     LTKSESNKILEAKEISDSLVPTEQSAIKAVESNDKSKAQSIIFGSDYINSQEKMDSLI
                     NEFQEDIVTRSNSKIVEVKKELQSLILRTIFILSLLIILTIIEYTVIKLKIVIPINKV
                     EKHFSRIASGDLRTSIDVEESKSEIGLLVSSVKKMQSMLLNYIDLIDSTLTSIAKGDL
                     RVEIDQEFIGDFKSIKISLESIINSFNGDFSEINLSAEQVASASEQVAAGAQALSQGA
                     TEQASSVEELASTINEISDGIKKCADSASLACEVSDQSASQVGFGSRCMDDMMTSMGE
                     ISEKSSEISKIIKTIDEIAFQTNILALNAAVEAARAGQYGRGFAVVADEVRSLAGKSA
                     KAAQNTAILIEEAIKTVENGVRIAKETANALDLVVNGVEKTTNYINGISSAVHSQEVA
                     ITQILSGIEQISIVVQMNSATAEESAAASEEMSAQAQILKELVEKFHLKESEVRESSW
                     V"
     gene            complement(45298..46257)
                     /locus_tag="KR231_000541"
     CDS             complement(45298..46257)
                     /locus_tag="KR231_000541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diguanylate cyclase"
                     /protein_id="HBH0002957.1"
                     /translation="MKNKQQGTILVVDDSVLMCDLIDKTLTKDNFKVKKAFNAIEAKE
                     FIEEFIPDIILLDIILPDNSGFEFCKEVKSNARTADIPIIFITSKNTDTDIVKGFGVG
                     AIDYMVKPFSMTELKARVIAHLEVKKSQDKLKKINNELESSLEKLNRLVVRDYLTGLY
                     NRRHIINQLMEQRRINKYSETSISLILGDIDDFKVINDTYGHEAGDFVLTVISSIIKK
                     NCRQIDTVSRWGGEEFLIMLTNTPIEGAKILSERIRKEIKEFDFNYKEHKIKCTITLG
                     VVEVNSNISLEENISLADKAMYEGKNLGKDCSVVSTMKGLKKI"
     gene            complement(46393..46911)
                     /locus_tag="KR231_000542"
     CDS             complement(46393..46911)
                     /locus_tag="KR231_000542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine-binding chemotaxis protein CheW"
                     /protein_id="HBH0002958.1"
                     /translation="MRFPDDPYLDYGLIDEGIKYLKFRVDEQDFGVELEKVIEITGNQ
                     EIIFIPELPTYSKGIINLRGKIIPIIDMRLRLKKDELMTTNCMYIVVTEIKDLVVGFV
                     VDRVDDIVSLEKSKISPPPRVTIEYSDYFVSGVGELEGKIITLLDLEKLLTDKDEVLI
                     DELINGFDCTIM"
     gene            complement(46954..47439)
                     /locus_tag="KR231_000543"
     CDS             complement(46954..47439)
                     /locus_tag="KR231_000543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chemotaxis protein CheD"
                     /protein_id="HBH0002959.1"
                     /translation="MNREIVVNIADMKIAYRPNVLVTYALGSCVGVCLIDKVAGIGGM
                     LHVMLPYSKDAINIENKCKFADTGINELIKSMENIGANRIYIKAKIAGGAQMFLGSSN
                     SVIASIGHRNVEAVKKTLLGLNIPILAEDTGMNYGRTIRFYTETGELLVDSINKGKKK
                     L"
     gene            complement(47436..48053)
                     /locus_tag="KR231_000544"
     CDS             complement(47436..48053)
                     /locus_tag="KR231_000544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chemotaxis protein CheC"
                     /protein_id="HBH0002960.1"
                     /translation="MINYLELDDVHIDALREIGNIGSGNAITALASMINSNVEVLIPM
                     VKILEYNEATNLLGGPENKVVCILLDMKGDINGMFMFLLDESITQLMLSSLFNKEEAF
                     LDEIEAIEISAIKEIGNIMASSYVNAIASMLNMTISVSIPDICIDMVGAVLNVPMIRF
                     SDVGDKVLFIENKFKMSDNYFTSHILMIPEMSSLREILVRLGLEV"
     gene            complement(48118..48480)
                     /locus_tag="KR231_000545"
     CDS             complement(48118..48480)
                     /locus_tag="KR231_000545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HBH0002961.1"
                     /translation="MENKILIVDDAIFMRMIIKEALSKSGYNNLIEANDGEEACNIFK
                     YEKPDLMLLDITMPKKDGLEVLREIKKLDSSAKVVMCSAIGQENMIVEAIKLGALDFI
                     VKPFKTETLVKVVDNALK"
     gene            complement(49224..49721)
                     /locus_tag="KR231_000546"
     CDS             complement(49224..49721)
                     /locus_tag="KR231_000546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="effector binding domain-containing protein"
                     /protein_id="HBH0002962.1"
                     /translation="MNYEIVEINEKIVIGISKETTNKDGQAVNDIGELWKKFMGKGIY
                     NAIKGKKNDKTIGLYTDYQGDFTSPYSFVACCEVNSNSDKEKNLEELNTNNTVGESII
                     SKVIPAGKYAKFVIVGGQKEVGDFWFEFWQMDFDRTYISDFEEYQCNTFDTKKQEVHI
                     YIGIK"
     gene            complement(49896..50807)
                     /locus_tag="KR231_000547"
     CDS             complement(49896..50807)
                     /locus_tag="KR231_000547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YafY family transcriptional regulator"
                     /protein_id="HBH0002963.1"
                     /translation="MKINRLTEIIVILLNKKLVTAKELADRFEVSTRTIYRDIETLSM
                     SGVPVYMTKGKGGGISLIEEYSIDKAILSKKDKESLIVALKTLQATKYPEINSVVNKI
                     GSIFGEQNFSNWIEIDFTEWGSNFNEDDKFTKIKEAILRRNTINFNYVNSLSSQTNRT
                     VEPLKLMYKSKTWYLYGFCKLKDDFRIFRISRIRNLSIKDEVFSRKIIEEVCLNDSKV
                     IKENTITLKLRFKEKMLFRVFDDFNKDLITKNEDDTYDVITEFPIGEWIYGYILSFGD
                     NVEVLEPKDVRDNVITRLRELSKIYSL"
     gene            51732..52583
                     /locus_tag="KR231_000548"
     CDS             51732..52583
                     /locus_tag="KR231_000548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3100 domain-containing protein"
                     /protein_id="HBH0002964.1"
                     /translation="MEINKKHFIQVFLTCLILVVICEFIGQRTIAIGKASIVLFPMLY
                     AVIIGLIITPDLLGKKIKALKKVVGEKEINIAGEVVGIALVMLGIKYGTTVGPNIDKI
                     IQAGPAFIAQEFGHILAPIVALPLALMFGMKREAVGATASISREPSLGVISEKYGINS
                     PEGSGVLGTYLMGTVLGTIYFSVLGSISIYSGLHPYALGMACGVGSGSMMTAAAGSLS
                     TMVPPEMADTILAYAATSNMMSSITGIIFLVFVSLPFTNFMYKILEPKFSRNKKTKEI
                     KSTEGEC"
     gene            52587..53057
                     /locus_tag="KR231_000549"
     CDS             52587..53057
                     /locus_tag="KR231_000549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0002965.1"
                     /translation="MFANLNLKKSSYQLLVMSVIGVIILIGQRISVGTSIVTALPGMV
                     MLILAAMAAMIIKDLFPKSIFPAFGFATIIGLLLSMPYSPTSEVFLTNTNNINFMAIT
                     TPLLAFAGISVGNKIEALKEMSWKIVIISLIVFTTIFFACASIAHIVLSIQGKI"
     gene            53070..54380
                     /locus_tag="KR231_000550"
     CDS             53070..54380
                     /locus_tag="KR231_000550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HBH0002966.1"
                     /translation="MNKEQLKSLVIKTIDENREKILKIGQGIYKNPEYGYKEFKTTEA
                     VSNFFEQELNLSVEKNIAVTGCKADANSSKKGPHISILGELDGISCKEHKDANEIGAS
                     HTCGHNIQIAGMLGAAVGLVKSGVLEHLDGKVSFMATPAEEFIELEYREQLKKEGKIT
                     YFGGKQELIKRGYFDDIDISMMFHASDLGEDKALVGPESNGFVGKKVKFIGKESHAGS
                     APHDGINALNAAMLAINNVNALRETFKESERVRFHPIITKGGDIVNVVPADVHMESYV
                     RARTINGMIDANERINKALMAGGMAVGADVEITEIPGYLPILRYKSLDNLFKNNLEDL
                     GLKGKVIDGGDFTGSFDFGDVSHIMPTLHPMIGGVKGALHTRDFEIVDEDLAYIIPAK
                     AMALTVVDLLFDNAKDAKDILDTFTPVMTKEEYLTFLEKHDKTL"
     gene            54592..55338
                     /locus_tag="KR231_000551"
     CDS             54592..55338
                     /locus_tag="KR231_000551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HBH0002967.1"
                     /translation="MFNAGNRIINTWLYPIQDGFVLIDTGYENGFKHFKKRISKFNIK
                     IKDIRYIFLTHAHDDHVGFLNQILDESPNTKIVMHDKALEILYKGQNSFIGGCTSRTA
                     FLFCQIMKLFGKGEHSFSPLKQEFEKRCILVSDKNRKEIEKELNGKIIDTPGHTADSI
                     SLLIDEGVLFCGDSAMNGFPSTHKITIFAESKLEFIQSWKTIINTKPKMIYPGHGKPF
                     EYSKLEQNLIYVNKINLYPLHNSKDIHRFL"
     gene            55700..57241
                     /locus_tag="KR231_000552"
     CDS             55700..57241
                     /locus_tag="KR231_000552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbgT family transporter"
                     /protein_id="HBH0002968.1"
                     /translation="MNDNVVKKKNFFDRTLNRIETVGNKLPDPVTIFLGLCVLLLILS
                     SLVGSMGISVVHPGTGETITAVNLLTVEQLQILLGNIVSNFQGFAPLGLVLVTMIGAG
                     VCDKTGLMTATIKASVSKIPETRVTLVVMTIGMLANIASDAGTILFPPLAALVYLGVG
                     RHPLIGLFSGYAAVCLGFAANIMISVNDILAASFTVPAAQMIDSGFQANATMNLFFMI
                     ASTFVLILLATWVTEKIVAPRFGKYEGNAELDVDGSLSDVEKKGLKKAGISILIYVAI
                     IVALSVIGKKPFLADPETGDLLSNNAPLMKGMVPIIALAFFIPGVVYGKTIGKIKKDK
                     DVVSIMASAMSDMGGYIILAFAASQFLQLFTNSNLGLILAVKGGEFLKSAGINGPLLL
                     IGFIILSCFINLFIGSASAKWAILAPIFVPMFMMVGYNPALTQMAYRIGDCITNPLSP
                     LFPYFPIILAFTRKYDKDAGMGTVIANMIPYSISFLIVWTILLILFMVFNIPLGPGIL
                     PSYSM"
     gene            57276..58382
                     /locus_tag="KR231_000553"
     CDS             57276..58382
                     /locus_tag="KR231_000553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20/M25/M40 family metallo-hydrolase"
                     /protein_id="HBH0002969.1"
                     /translation="MLDKNRLINNFMDMVRIDSPSNQELEMSKWLVNYLKERNIDAII
                     DDAGEKYGGNTGNVIAYIKGEEGSRPLCLCAHMDQVQPCLGVKPILDGNVVRSDGTTT
                     LGADDKAGIAAILEALEHVITEKIPHRDIYLCFTICEEAGMHGVKNFNPDNLPCKDMV
                     ILDSGGAIGSIAYKAPAQQSIKISFHGKKAHAGIEPEKGLNAILVASHAISNMHIGRI
                     DSLTTSNIGKIEGGGATNIVTDKVTLTAEIRSHIPETLEYELNHMEKCCKDAASKFNT
                     TYTFEHSMSYPSFELSRDSHVFKLSEEAIRQVGVVPNPMVIGGGSDANILANLGYNCA
                     ILSLGMYDVHTVNEYVNIDELYDTAKIVYHMIKL"
     gene            complement(58713..59999)
                     /locus_tag="KR231_000554"
     CDS             complement(58713..59999)
                     /locus_tag="KR231_000554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HBH0002970.1"
                     /translation="MIVGIIGPSDSGFKIKDDLKQIDSDLKTKIYVREKVVDTIEVIS
                     KCEDECDAIIFTGCAVYEFIKSKYEISKPHSFVPRSGTSIMKAFWAIKSANIKLDKFS
                     IDVVDRYVVEDALKEFDIKATSVFCNPFSLEVGESELVEWHIKLFEENKTDIMLTGFG
                     AVYNELKERGYPVFRLQATIQLIKESYDKVKSEYALSKARFSQIAVEILSLIDYKEKI
                     DNYYSDMIKKSDMDKLVVNYVRSIQGSLFLLGRNDYVVFVHKGVADNEYNYDKLFNLK
                     REIKDMGFSLSIGIGTGVTAYQAENNAHKALRHSIDSKEIGIYLVDEDENIRGPLASE
                     NELNYSLMLSDEKVIEISKKTGMSCESVAKIIAINENRKSKIYDSKELAEYLNVSERS
                     ARRILNKIVNAGLGRICAKETSIGGGRPKNITEILF"
     gene            complement(60122..63220)
                     /locus_tag="KR231_000555"
     CDS             complement(60122..63220)
                     /locus_tag="KR231_000555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009904951.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional diguanylate
                     cyclase/phosphodiesterase"
                     /protein_id="HBH0002971.1"
                     /translation="MDVINLIDELDEIVYVSSLDTYELLYINEIGKKAMGLNDISHLK
                     CYKALQGKDSPCEFCTNSILKEDEYYIWENTNTRTNRHFILKDKLIKWEGKHARLEIA
                     LDITEKEDISKSIAEKLEIKELLVGCIKHLITESNFSDAVNLVLTNIGKFHKADRAYV
                     FEVSEDRTKVTNTYEWCNEGVDEQKQALTNLDINELKNWFLLFEQKGFVIIDDIENIK
                     EEQPIEYEILKPQKIESLMTSSLKQDDKVVGFIGVDNPHKAVGDTSLLTSLSYFLLTE
                     MKKRKVENKLNYMSYYDFLTGAYNRNKYIKYIDNFQKGKVKSIGVVFVDINGLKDIND
                     NFGHANGDSAIVSACVIIKKYFHSYNVYRIGGDEFVVLCEDISKQLFEELVSWLSEEF
                     KDEMIYSVAVGSIWSDDNIDIHKLIKVADERMYQDKKRYYNKNKLRNNEMKVISDLAD
                     STNNILFKHKELVDKVYFDDLMIKGYSKAYEKLAYNTYDIILSICIDTNLITPIYQSE
                     SNIFSFPIKENLEKTFSYIKKYLIHPDDIILFNDNHLLKSLDSLNNSKQDDLELNFEY
                     RRLGIDKKYYWALIYMLKISSKNKLGEKQTHILVAIKNIDYLMQLHKNQKDTLTGLYN
                     YESFCEQISLMLKRYPDKRYAIIMMDIDKFKVINDIYGVRGGDKALIYVAELIQKNIG
                     SNGICCRMYADVFCIFYESYSDRDIHKVIYKIKNSLNRKKFEYMLVPCFGVYRILDNH
                     IPITNACEMAGYAHKKVKKQSINNYIFYDDTIRNDALEEKQMEREMEYALENGQFHVY
                     LQPKYNLNANKIVGAEALVRWVHPEKGIIPPIKFISLFEKNGFIIRLDMYVWEQVCSL
                     IRKWIDLGEEPVPISVNVSRLHLHNPHFKEIVLSLINKYSIPKSFLELELTESLFIKN
                     IKLFTKIIADLRMDGIVLNMDDFGSAYSSLNMLKNINIDTLKIDCGFFNEEGITDREK
                     IVLKHTIAMAKDLDMDVVAEGVETKEQAEFLVSLDCVVIQGYYYCKPIPSSDFEKLLY
                     QK"
     gene            63945..64097
                     /locus_tag="KR231_000556"
     CDS             63945..64097
                     /locus_tag="KR231_000556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0002972.1"
                     /translation="MKIFSFLLFVVGICFCIAGFMGHSSAFSGATLSFFATTMIAVRQ
                     VKTKKK"
     gene            complement(64390..65094)
                     /locus_tag="KR231_000557"
     CDS             complement(64390..65094)
                     /locus_tag="KR231_000557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBH0002973.1"
                     /translation="MEIKPLVLIVEDDKPICKFIKVSLETQNYRCVETDNGGTAISLI
                     HSLDPDLIILDLGLPDIDGIEVIGRVRACAKTNKIIVVSAREHERDKVEALDGGADDY
                     LTKPFSVTELLARVRVALRNKAQQDNINNDAPKSFEVKNLKIDYENHIVSINGEEIHL
                     TPIEYKIIELMSKYSGRVLTHKFIIDKVWGNYYESENQSLRVFMASIRRKIEKNPAQP
                     EYILTEVGVGYRMADE"
     gene            complement(65085..66692)
                     /locus_tag="KR231_000558"
     CDS             complement(65085..66692)
                     /locus_tag="KR231_000558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4118 domain-containing protein"
                     /protein_id="HBH0002974.1"
                     /translation="MKKERLQHEDLKEYDYDEDGYLSKKIIIKDFIKTILVMTIATGI
                     SVVFEKVGFNESNIILVYILGVLFATSITYGYFFGILSSVIGVLSFNFFFTHPLYTFL
                     AYRKDYPMTFCIMLMAAIITSTLTSRIKREVRLSHKREKMIRLLYENNKTLLKAKNKN
                     QIIEFCGSNLVNILNRTVIVTIADENNNLGKPSIYICNNDGSENIFHSVLEKEAIKEA
                     FRTGNPVGIGTKYCKNSSAYYFPIKGQESNVLGVIGVACFKIDIITENEKILLEAVST
                     QVALAIDRENLFEKNKKANLEAERERLRGNLLRSISHDLRTPLTSILGSSSTILENDD
                     VIDKETRVELLKNIYEDTSWLTHSVENILSMTRIDEGKLDIEKRPEVVDEIIAESILR
                     VKKFANSRDIKTNIPDEIIIVHVDVLLIEQVLVNLIDNAIRHTPKNSKIELTVKKESN
                     QVLFEVADNGKGIPNEDIGNIFNRFYTKNKSRNLERRGIGLGLEICKSIVEAHGGEIV
                     AFNNPSGGATFRFSIPMYDEEGKDKWK"
     gene            complement(66946..68124)
                     /locus_tag="KR231_000559"
     CDS             complement(66946..68124)
                     /locus_tag="KR231_000559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0002975.1"
                     /translation="MEKLSDKRRVKAVSMETFVFIVLLAVGFGYVGSIMGAGMMFKVI
                     MSTAHALLLDTVFLIMAMAVLAGALSALLSEFGVISLVNKIFKGLMRPIWGLPGASIA
                     GVVATYLSDNPAIIPFAKDKTFTQYFKKYQVPALCNLGTAFGMGLIVTTFMIAQGKEY
                     VLPAIIGNVGAIIGSIISVRIMLTFTKKYYNYDPKNDTEKQINDKGAKLEEFREIRDG
                     NVFQRTLDAILEGGKLGVEMGMAIIPGVLVVCTLVMLLTFGPSTDPATGQAVYTGAAY
                     EGIKLLPAIGDKISFIIEPLFGFTSPEAIAFPVTALGAVGAAISLVPEFIKSGAITPN
                     DIAVFTAMGMCWSGYLSTHIGMMDALDARPLAGKAILSHTIGGLCAGICAHFIFMLVG
                     "
     gene            complement(68350..68844)
                     /locus_tag="KR231_000560"
     CDS             complement(68350..68844)
                     /locus_tag="KR231_000560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HBH0002976.1"
                     /translation="MHLFIEVIAAFFTALSFGVLFNMKGKNLILAGIGGSIAWFSYKF
                     LLNMGVTENLCFFIATVCFAIYCELCARIYMTPATTLSVCCLIILVPGYGIYNTMYSV
                     LTNNYIKAVEYGVSTLSCASSIALGLVFITTVFRKVNLYGVLTKIKENEKYKKSINKI
                     KQQK"
     gene            complement(68845..69606)
                     /locus_tag="KR231_000561"
     CDS             complement(68845..69606)
                     /locus_tag="KR231_000561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HBH0002977.1"
                     /translation="MDIDRILNFSSNAGKAMLQSGGETYRVEETIARICQSFGIDHVD
                     VFATPTAVMASVFVDGKLHSAIKRISSRRVDLNLVHEVNSLSRAISINNLDIELCEKI
                     LDEISEDNYYSDLITIFFAGIAAATFSILFGGNVEEFIAAFTVGILTKFVIMYLSKSS
                     LNDFFVNAIGAVIIASCSILILKLGFIKTLDHLIAGAIMLLVPGLALTNALRDLLDGQ
                     LISGLAKLAEVFFVGVSIAVGMFLVLGLYFKLGGI"
     gene            70328..73162
                     /locus_tag="KR231_000562"
     CDS             70328..73162
                     /locus_tag="KR231_000562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HBH0002978.1"
                     /translation="MLRKDKVLLSLHKLCENMTLKDLQSDKTGFTTIEIANHSSLDRS
                     NTSKELNNLYNEKKVLKISGKPILFLHASIIENLIGRTLNSDEFSINNCNELLKSSKN
                     DSEDIFSTLLGHDSSLKLPIEKAKSAILYPPKGLNTLLIGPTGVGKSTFAETMYKYAV
                     ESKIFSSESKFVVFNCAEYAENANLLLSNLFGYVKGSFTGANKDKFGIVAQADGGILF
                     LDEIHRLPPEGQEMLFLLMDKGIYRRLGESDIVHKANVFIVCATTEDIHSSLLGTFLR
                     RIPVTINLPALQDRSLKERLSLIKYFFIIESKYTNATIKVHKDVIKSLLLYDCFGNIG
                     QLKSDIQLMSARAFLNYKTGLKDNIEIDLSLVPDYIYIGLLKLNENRSNLNKLSELDY
                     MLFYEFNGNNLEVEYTKELSKYNIDTSNNGFKYSTEIPYLENDIRSMFINYMEKYSTK
                     LLSISSVTHSDYTSNEIFKVINPKIYYAVEHSLKEAEKISRNKYTKQTYIALSMHISA
                     LIENINQDTYNPKYNLYNDKIFLDKDLNIAKIVLSIIENDLQTSLPKDEVKFISMFLN
                     SMYLEPNNQSESIGVIILAHGNSTASSMCDVANSLLGTNHCNAIDMPLDVKVSTILDK
                     TIELVKECDEGKGVLLLTDMGSLIAFGELISEKTKIKTRSIEMVSTPIVLEAVRKSTL
                     PEMTLDELANSLSSLNPYIGRAAIDSTEINYPEKSREYVIITTCITGYGSAMKVADFI
                     NSSLKNISKYNINLVPHNIESFKMYKNKFSNTKILAVVGSVDFNVANTPFIHIEELLN
                     GYGLDMLNKIIEGTFNANSITNIKETNLSYNSLIINFMTQNLELLDSVKLFNYVNSSL
                     FTIIELIDENLKSKFKLGYILHCSFMIERCFKNTTFPYNNITELISKNHELYSLIREA
                     FKPTEAYFNILIPDEEIAYIIDMINEYLNK"
     gene            73205..74449
                     /locus_tag="KR231_000563"
     CDS             73205..74449
                     /locus_tag="KR231_000563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase"
                     /protein_id="HBH0002979.1"
                     /translation="MEDEILKGKIKQLTILALIFIFITPVFAFADTPPVPNSSRAALL
                     IDQETKRILFEKNIDEKMPLASLSKMMTFLLAIEAVDKNQVKETDMVKIDKSTASVGG
                     STCKLKDGDEISLGELMQGLMLVSGNDAAIAIAKHIGKTEKNFVNMMNKKAEEIGMID
                     TYYFNPNGLPIYTDPEHKEPPIENMSTAHDIVTLGKYMYDHYENQVTRITTMQVYNDT
                     KKDFTHYNTNPLLVSVPGVDGIKTGYTDNAGYCLAFSMMVPKDAKNERNHRLIGVVLG
                     DGNKKNRISSSATLLKYGKDNFHSKKIAHKGDIIETPCVDGIDDFKITVKVDKDLYGV
                     VSDNENINPKVVFKNMNYPIHKGDIVGVVKYYNDSGKFVGSVDVKSESNIGCIPLKDK
                     IKIKVAKINKKLEIKNSVCFKA"
BASE COUNT        24850 a        13051 c         7914 g        29253 t
ORIGIN      
        1 ccataataaa atcttataaa tattacaata aaatattttt ttccatgata taccttgata
       61 aaatctctgc ttctttaagc agtaactttg agttgaatca ttatagtgat ttataacatt
      121 tatagaaatg ctgttataga tttatattta aacactacaa atggaaattt aactattata
      181 aaaaacaatc attagataaa atgattctta caacaaaagc atttctattg tagatttatt
      241 agtaaataat aaatctacaa tagaaaaaac tagaagtaca gtatcataaa aatataatta
      301 actgtacttc taaattattg tttttaaaat aaattttcat tcattaaaaa atacacataa
      361 atatttccag actccgattc agcaaactta tataagttca ctttttattt atcatcaatt
      421 attttcatat acttctttta tctcatcttc acttaagtca aaatcattaa atttatttaa
      481 tatgtcatct aatttaaaac catttttttt caacattata attattttat aatctttttc
      541 ttttgcaact ctaattgctg tctctctttc aatctcttct ttaaaatttc tacttttatt
      601 catgatataa gcacctcttt tcagatttaa taaatattct tcattgctac ctaattcttt
      661 taatctatca agtgcttttt taataataga atcattctta gctataactc ttacatctaa
      721 gttagaagga ttactaataa gttttcccca tagcataatt ctatttacta tatagtcaga
      781 tttatgaatt tttggaagct ctataaaata taatgcagtt ttactagaat aaatatctgg
      841 atgcccgtcc attgttaatc tcaggcaatt tacataatct tctatgtgat tatattttac
      901 atgatttagt atatgtattc caatagtttt tccaatttct ttatactctt taccttcttc
      961 taactttcta ccatgtacac gactaagata atattcagct ctttccaaat aatcgttctc
     1021 aaaagctctt tgcatctcaa tatttatatg attattttct tcatcttcag ccaaaatatc
     1081 aagtttaggt cttttctctc caatgtaatt aattgttgga tcagtttcaa ctctaattat
     1141 tctctttatt tgagtgaacg gtttgatatt cctgttagca tatggagcat cttttagaat
     1201 atcatttata aaatttacaa gtaaatcata ttcattattt aaagtgaaca atgatttaaa
     1261 tacctcatca tactcgggct tagcatatcc atcttcagtc acaacttctc caacattttc
     1321 attagtcaaa atctcttttg gaattaacgc cttgatttta tctaattcat cattagaaaa
     1381 actacttcta ctaagtatat catttaattt tttggtccat tctttatctt tttcttcaat
     1441 tatagttcgc ttatattctt ttgatgtttt aataatctta gatttttctt ctactttttc
     1501 tatcatttca acacctctct ttttcctctt ttgtatttat catttcttga aattaaacta
     1561 agtcactacc tcttttaaaa gttcttgctc cataaacact ttcttaaact ctaatgtctg
     1621 tgtatgtact tgacattctc tctctatcta aagttaaata aattaatcta tgtatagagg
     1681 gtaagtccaa aaataacata aaacactaat taatcattta taaagcatta attaatcact
     1741 gacaatgctg ttattgtcac cacatagcac caacatagat tcttctatta tagggcaatt
     1801 atctatgaaa aatagactca taagattaga aaatgtactt aaattttagt tcatttaaat
     1861 attcattttg aagaaagaaa tttaacttta gactaaaaag gaaatatttc aagaggatta
     1921 agaaattttc ttaaagggat aataattttt atgaaaatgg aacaaatatg aaaataaagt
     1981 tatgattttt acagccataa ccttaccaac aagcacttaa ttatcactca aaaaataaac
     2041 gtttatttaa agaatgcaca taaatatttc catgttcaaa acacttctat gatatattta
     2101 ttaataaatc taccatacaa aaaactagag gtacattaat cataaaaata tgattaactg
     2161 tacctctaat tatactcatc ttttcataaa tttaatcact atgcatcaac atatcaacat
     2221 attgattaaa cttatcttat ataacaatat cttagctact aatataatat atattagtct
     2281 tgaataatac tttctcttga ttcaatttct tttgaaatac tagctataaa ttcatctaat
     2341 ttaatactac ctatttcacc tttatctctt gatctaacag aaacattatt atcagctact
     2401 tctttttcac ctactattag catgtatggc actttttcaa gctgagcttc tcttatctta
     2461 aatccaattt tttcagctct atcatctaat tcaactctta tacccttatc aaataactct
     2521 ttcttaactt catttgcata atccataaat ttatcagata taggaagtat cttaacttga
     2581 gttggagata accaaactgg gaatttacca gcataatgct ctattaatat acctataaat
     2641 ctttctatac taccaaaagc aaccctatga atcataactg gtctatgctt ttcaccatct
     2701 tgaccaatat aagtattatc aaattgtctt ggaagctgca tatctaattg gatagtacca
     2761 cattgccaag ttcttcctaa acaatctttt agatggaagt ctatcttagg accatagaat
     2821 gctccatcac cctcattaat agtatatggt agacctaact cttctaaagc ttctcttaat
     2881 ccattttctg ctgcttccca ctcttcgtcg cttcccatag agttctctgg tcttgtagat
     2941 aattctaaat tatattcaaa tccaaaagtt ttgtatatac catctattaa gttagctact
     3001 ccttttattt cgtccttaat ttgctctggt aacatgaata tatgtgaatc gtcttgagta
     3061 aatgctctaa ctctcattaa tccttgtaat gcaccagata actcatgtct atgaactcta
     3121 ccaagctctg caactctcat tgggaaatct ctatatgaat gtagttgaga gttataataa
     3181 attaatccac caggacagtt cataggtttt atagcataat cctcatcatc tattttaact
     3241 gtatacatat tttctttgta atgataccag tgtcctgaag tctcccataa ttttctattt
     3301 aatatgattg gagattctat ctcaatatat ccagcttttc tgtgtatttc tctccagaat
     3361 tttaataatt catttttaag ttccatacct tttggtaaaa acatagggaa tcctggacct
     3421 tcttcaggta tcataaataa tcctaattct ttacctaatt ttctgtggtc tctcttttta
     3481 gcttcttcta gtaaatgtaa gtactcttct aagtctttgt ttttctcaaa agaagttcca
     3541 tatattcttt gaagcatctt attattttcg tcaccacgcc aatatgcacc tgctacactt
     3601 tgtaatttaa cagcttttac ctttttagta gatggtaaat gtggtcctct acataaatca
     3661 gtaaaatcac cttgcttgta gaaagatatt atttcacttt caggtaaatc agatataagt
     3721 tctaccttat agtcttctcc ttgttctttc ataagctcta aagcttcatt tctaggaagt
     3781 tcaaatcttt ctatttttaa atcttcttta gctatttttt tcatttcagc ttctattttc
     3841 tctaggtcct ctggaactaa tctatggtct aaatctatat catagtagaa tccattttct
     3901 atacttggtc ctatagcaag ctttgcttct gggtaaagtc tttttatagc ttgagctaat
     3961 atatgtgctg atgtatgtct aaaaacttcc ttaccttctt tatcttcaaa cttaaataaa
     4021 ttcaagtcac aatcagtatc tataatgtgg tccagaccta caacctctcc gttcacagac
     4081 gctgctacca catttctagc taatccttca ctaatggatt tagctacatc cataacagaa
     4141 atagcatttt caaattcttt tattgagcca tcttttaaag caactttaat cattgttttt
     4201 tcctccttat tgaaataatt tttagatttt ttgtaataaa aaatcgcccc aaatatgttt
     4261 gggacgatat taattcgcgg ttccacccaa gttggcgtat acaagtatat acaaccctct
     4321 tgatgactat aaggtcgtca cccgagcact ttcacgtata gtacaaaaca aatactgcta
     4381 ataagctcag ctccaaggta gttttcaaat agacctatta catgggctct cagccataga
     4441 cccaaattct ctgagaatgg tttctactct actcttcctc ttcaacacta tgatttttaa
     4501 tatattttca ttataacaga tagttataca tcaatcaaca ttaatgtaat atattaatta
     4561 cccattattt ttcatctcaa tcagctgtaa accaatattc ttatattttt atattaaatt
     4621 aatctcttga tttatagtga tattataata ttttcataaa tttaaaattt ttaaaacgta
     4681 tccacatgca tgatagatat gactagataa atactaaaac taatttttat taaaactaac
     4741 ttctaatttt tgtactcttt ttaggttttg tatacttaaa tacaatcaat acttaatata
     4801 gttaataagt agtacagtaa atacttaaat actattaata agtaacacaa tcaaataaat
     4861 aaatacaatt aatatctaaa tgctattaat aagtaattca ctcaaatagg taaatataat
     4921 tagtacttaa ataaatgcta cttctcatat atttaaataa acatagtaat taacccttga
     4981 gctataccta ttaaaaaccc taagacaagc cccaaaaact ctatatgttt taattctttc
     5041 ttagctattc ttattattat ctcttccaat tcatataaat ctagttcatt aatcttatct
     5101 tcgaccattt tttgtatatc tatacgttca tttgctttat ttattatatt tttactcaat
     5161 tcatctatac tttgcttaac ttcagactca attatctctc ctagataatc ttgtatcatg
     5221 ttttttatac cactcgggat aaatgaaact ttctcatgta ttataatttt tacccttgct
     5281 tttatgtatc ttacaacttc ttccttatct tcgtcagtaa tgatatttgc aagtatttcg
     5341 tccatagaaa gaaattcttc ttgaattatt tctcctacat ttgctgctat ttctgctctt
     5401 ctctttggta taagacctac tatttctata tttaaaatag gtattttaat aggctctatt
     5461 ggtctaaata tcagtcttat agcaactaca ttcgtaacat aacctataaa tccaccaata
     5521 acagctaata tcagtatcct aattaaatta tccattataa aattactcct tatcaattgt
     5581 atatttgcca gctatattgt attaatcaag tagatattct ttatacttaa taacactagt
     5641 tatactatag ctttatatac aattataagt cttttgtgtc gatttaaaaa gaattttttt
     5701 aattttatat ggatagcttt tatatgctta gattctagtt ttccataatt atactaactt
     5761 tattttcaaa aattgcttct acagtatcta taatttcctt tgagcaatta ttatttaaca
     5821 aatccaatat ttctattttt ttgggacata gagttaataa ggtacttatt aaaaagtcct
     5881 cataatttaa attttctctt attaccatat ttataatttc ttcatcatct atactgtcta
     5941 tcttatttcc atttttatcg tataaaacaa atgtattatc ttccattata tgaactttaa
     6001 gcaaatcaat cttttcttct tgagtatcta taaagtattt taaaactctt ataaattcat
     6061 cttggtcttt ctttattaaa tactcctcaa ctgcaatatc acctatagca gaaatatatt
     6121 tcataaattc tctcattcta aatctaataa aaccttctac atttataaaa tcattttctt
     6181 ctatataatt tctcacccta gtaaatactg tttctctcat aaaaatctct tttttagcaa
     6241 atatgttcag tgaatatatg tatatattat ttttatcttc aggatatgta cgcccatagc
     6301 attttagaat gtattctttc aaaagtttct ctttcattat acttattatc atactagtta
     6361 tttccgttga tatctcatca atatttaaag ctctttgttc agctttagta ccattaagta
     6421 tttttttatt taacacttct tgctttgcag aatctatcac tacttctaca atgtcattcg
     6481 tatatattaa tctatcgttt acattattat tcctcaaaaa tttcatggaa gaaatattat
     6541 ccttctcaac caaagttatc gctcctttct tgtcatgaga ggaactatag aacctatatc
     6601 tagtaaattt tcacagctaa gtgtaactat ctccttgttt ttactttcta caaaactttt
     6661 tatacgttca tagtcaggat gttttttaac atctccacaa aaagctagtt tatccttaga
     6721 aatcaaccct gtacatccac ctataaatcc ataattcatc tcaaataaat ttatgtgacc
     6781 tttttctatc aataaacact ctatttctgt attcttcata cttttccaaa tacctttatc
     6841 tgatgttatt atagacgttc tatctactat acagattgag catttagaat agccctgctc
     6901 tatatttatc tttttaagtt tattattttc aatataatct aatattgctt tgtcagtata
     6961 cttaaaattg tgtatagcat agtcaccaac tatcgcaata ttgtaaggta tatcataagg
     7021 gtatctattt aataaattag cttctccctt aattatatta aatttatatc tacttaataa
     7081 ctctttgtat tgattatata cattcggcgc aacaattata tctccttttc ctaaattaca
     7141 aatacatata tccgggtgat attttatgct ttcatataat tctttacatt ctattgtttt
     7201 tattatctct atatttctta attttaattc attttccatt agataactaa ttcttttgtc
     7261 caccaaagct agacacaaat cgtcatctag tataaatggt tctcttgtaa attccatttt
     7321 ttactccttt ttcttttttt tgataaattt tttatgtgaa tataaataaa gtgtgtagca
     7381 gaatttttct gcccacacac ttattgttat aattttatat agttaatcta agcttaatta
     7441 gtatagcttt gtacagttgg ttcaaattta ataaatatat ctttttatca ctaatctaaa
     7501 cttaagcagt atattccgta cagttagcac aaatttaata aatatatctt tttattgcta
     7561 atctaaactc aatcaatata ttttgtacag ttagactaaa tttaataaat atatcctttt
     7621 atcaccaatc taaacttaag cagtatattc catactgtta acacaaattt aataaatata
     7681 tctttttatc actaatctaa acttaatcaa tatattttgt acagttagca caaatttaat
     7741 aaatatatcc ttttatcacc aatctaaact taagcagtat atttttataa tcttctacat
     7801 caataattaa tatgtatctt tcactttgtt atactctttt tttatgtatt ccaaaacatc
     7861 tggtggtata tttctactgc tctttgaagt caagccaagt tctccatctt ttattttaaa
     7921 ttccattact ttacttccct taaaaccatc ttttgcaacg ttctttatca gttcatatac
     7981 aggttgttct acatctttta taattgaact tattacatta tctggagcca tatcgtattg
     8041 gtctttatta atagctataa ctttacctcc attttctctt gctacctgaa tagctctttt
     8101 actatcatcc tctgtagctg aaaatacaac atctctatca gaatctctca tttcctttgc
     8161 aatagttcta gctgattcag ggttttcaaa tatatttgaa tacttaacta gtaactcagc
     8221 atctttattt gaagttttaa gcccctttct aaatccagat tcatacttat ctctactaga
     8281 accctcaact cctcctataa aaccaacctt cccagtatca gtcattttac ctgcaataag
     8341 tcctgctaaa tatccagtaa cattatcttg aaatgataca gaaattacat tagctggctg
     8401 aactttataa gtatagtcaa ctattgcaaa ttgctgtttg ggatattcag tagcagcttc
     8461 tttaattggc tctgcaaatc tggctccaac tgctattatc aaatctggtt catacttatg
     8521 cagtttttct atactctctt taaaactttt agaagtcttt ggtttttcaa gttttatcct
     8581 aacatcaaaa tcttcgtcag ccctttttaa ggctgatagt acattgttat tatatgattc
     8641 gttatttaag ttttcggtat ctaacaatac tccaatagtt tttcttacat atgaatcatc
     8701 ttctgtgtca tcttctttat tcttactttt actatttgat ttatcctttt ctgctgaagt
     8761 tggcaaactt ttagactcac tctgtttcga tttagcacta tctatattag aattattctt
     8821 atttacttta tcaaacccaa aatcaaaatt acatatagct aatataaaaa ttgtaaaaac
     8881 tactacaaag caagccatca atatcctttt tattttcaca aaattcactc cctgatttag
     8941 ataggtctga cctacatctg catatgtctt tctatatatg tctattataa catccaattc
     9001 acctcataac taaagtcata agtattcttg gatattatag tagattattt attgttctta
     9061 ttaacatatt ctaacacatc tggaggaata ttttgagaac tattttgggc aagcccagta
     9121 cttccagact taactgtgtt ttctataact tttccgcctt tataatttcc ttttacaaaa
     9181 ctttgtatca gattataagt aggattctca aaatctttta caatagaact tataacattt
     9241 tctggagcta actcatgttg gtctttattc gttgctataa cttttttatt ttttgccctt
     9301 actgcatcta ttacagcttt tgaatcatct tcagtagtag aaaaaataat atccactcca
     9361 ttatccatca tttttttagc tatagattct actgatttgc tatctttaaa aacatctgca
     9421 tactcaactg aaatatcctt tatactacta ttagaaaatt taacaccctc tctaaaacct
     9481 gattcaaatt tatctctact agaactcttt gttcctccta taaaaccaac cttatcgctt
     9541 tcagtcattt ttccagcaat taatccagct agatatccag atttattatc ttcataagaa
     9601 attgaagtta tattagaagg ttgcttgtca tactcatagt ctataattgc aaattgttgc
     9661 tttggatatt tcttggctac catctccaat ggttttgcaa atctagctcc tacagctata
     9721 attaaatcgt aattgtcatt acataaaata tctatactat tagaaaaagt tgaggaatca
     9781 tctgattcca ctttgtttgt atctatatta agtttctttt gagcattgtt taatgctaat
     9841 aaagctgaat tattcatagc ttcattattt gttccttcaa tatctagtat cattgataca
     9901 gatttttttg aattactttt atcgcttata tcacttttat tatctttgct agagctagga
     9961 ttattgcttg ggttattagc acacccaacc aacattccag ctatcattgc tacagttaac
    10021 atcaatatca atattctttt gaaacgcatt aaatttcact cctcatacat ttacgatatt
    10081 tttatatcct atttactttt acatcctatt tacttttaca tcctatttat aattttttta
    10141 tatacaattt acaagtacat tttgaaattt ttttaataaa tcttactata aaaaagtgtg
    10201 caatagattc ttatctattt acacacttcc ctacaaacta aatctaatat atcaacactt
    10261 aatttcatcc aaaataaatc caatttaaca tctcaataat taatattcta tcctaattta
    10321 ataaaaaaat aaataatgtc atccaaaaat atattattta ttttttaagc atatgatacc
    10381 agtaacacca ggaccagcat gtgcacctat acacacacca atttggaaaa atctaatttc
    10441 tttaggtctt aattcatctt gcataacctt agataattgt tctttttcct taaaatcatc
    10501 actatatcct atatatacaa tttggtctga taaatcatca ccacaatttg attttatcaa
    10561 ttccatcatc ttagaaatta cattcttctt tcctcttact tgagatattt gcgaaactaa
    10621 tccatctctt atttcaagaa tcggttttat atttaatata cttcctattg ctgccttagt
    10681 agatgatatt ctacctccct tttgtaaata ttccaatgta tctactgaaa atataacaaa
    10741 agccttctct tttaattcat ccaaaacagg caatatttca gcaacagact ttccttcact
    10801 tgcaagttct cctgctttta ttacaagtaa accagttccc atacaaagca agttagagtc
    10861 atatgtatat attttaccat ctacatcatt ctttgccatt acagcacttt gatacgtacc
    10921 tgtagctgtg gcagaccctg ctatataaag tatctctcta tcctcatttg tatatttctc
    10981 aaaaatttcc ttaaattggg cataagtagc ttgagaagtt tttggatata cattttcttc
    11041 tctaagcttt ttataaaatt catctccaga tatatcaatt ctatccttgt attctctttc
    11101 ctccagtata actgttaatg aaactatatc tatatcatat ttatctaaca aatcttttgg
    11161 cacgtccgat aaactgtcac agattatctt tagatttttc attaagtatg ctcctttctc
    11221 atttaggctt gttgaaacta cctcatattt gggtatccta tttgtcttaa agcctcgtac
    11281 actacaatag caactgaatt tgataaattt aatgacctag ctttttcaac atccaacata
    11341 ggcactctaa tacaagtatc catatttgct ttcaacaaag gttctggtaa tccctttgtt
    11401 tctttcccaa atactataaa acaattttct tcatatttca catctgaatg tgactgttta
    11461 gcctttgttg tagaaaaaaa gtatttacta tttggatact tttcttgtaa ttcttcaaag
    11521 ctatcgtaat attgtatatc agctatatcc caatagtcaa gcccacatct ttttaggtgt
    11581 ttatcatcca atgaaaaacc cagtggtttt actaaatgta aagttgaacc tgttgctgca
    11641 caggttctta ttatatttcc tgtattttga ggtatttctg gttctactaa tactatattt
    11701 aatgacattt taatcctccc taagtatcgc ttttatttat caaattttat tttataaaca
    11761 gaataacaat aatattatac tattatataa aataatgtta ataataattt ttatttcatg
    11821 tatataatag ttttttatct aacattttca caagtattat tatatcagaa aatccctctt
    11881 gtacaactta ctttctaaaa gttatttcgt ttcattaagt tctttataat aattacaatc
    11941 ttcttttatt gggcaacttg cacattctgg atttctagct ttacacattc ttcttccatg
    12001 aaaaattaat acatgatgtg agtgtgacca tctttctttt ggtatagctt ccataagtgc
    12061 aaattctgtt ttttgaggat ttggctcgtc cactattcct attctattgc taactctaaa
    12121 tacatgagta tctacagcta ttgctggatg attaaaagcg ttactaagta caacccctgc
    12181 cgtttttctt ccaacaccag gtaattttat aagcttttct aagctatcag gtacttcacc
    12241 atcatataat tcacatagct gttcagatgt atcctttatt ttttgagact tgcttttgta
    12301 aataccacaa ctctttatct ctttactaat ttcttcaatg ctcaaattag caaagtctct
    12361 agctgtgttg tactttttaa acaactctga agtaacttta ttcactctta catcagtaca
    12421 ttgtgctgat aaaatagttg ctattaaaag ttcaaaggct gtcccataat ttaactcaca
    12481 tttagcatct gggtacagtt tttctaactc gtctaaaatc ttatttacgt ctttttcatt
    12541 tgctgactca tttttaattt taaacttact tttagtttct ttacttgttt tttgtgtagc
    12601 cttattagaa ctactcttct ttgttttttt ctccgtttca ccttttttag tacttttttt
    12661 acttactttg atactttttt tatcttcttc aatatccata aaattctcta tatctttctc
    12721 atcaattatc tcatcttttt taccaatcat tttatctatt tctttttcat ttatctcttc
    12781 cttctcaatt atatctttct tattcattcc ttttttattt atctcttcct tctcaattat
    12841 atctttctta tccatttctt ttttatttat ctctttcttc tcaattatat ctttcttatc
    12901 tattcctttt ttatttatct ctttcttctc aattatatct ttcttatcta ttcctttttt
    12961 atttatctct tccttctcaa ttatatcttt cttatctatt ccttttttat ttatctcttc
    13021 cttctcaatt atatttttct tatccattcc ttttttattt atctcttctt ccaaaattac
    13081 atctttttca tttatctctt ttagatttac atttttcata attatccccc ttcaaaatac
    13141 caatttataa aacgctattt ataaatagtt taatcatatc aacaaaaaaa taaacatcaa
    13201 tatataaaac atacaaaata agaatttaat ttatatatat ttacaaaaaa agcaaaaacc
    13261 tattaaagtt cttgcttttt attatacata aatacccatt aaattctata ataaacttat
    13321 tcttttgaca cagtttgtat cttgctgaaa gatattaatt tttcttttac caatttcttt
    13381 atttcttcaa atttaacatc tgtcaatatc tctatagcct cttctactct ttcaacagta
    13441 tatatcttaa attttccatc tcgcactgca tcattaactt catctgataa aacgagattt
    13501 ctttgatttt ttctaggaat tatgacgcct tgctcaccat ttaacccttt agttttacat
    13561 atagaataaa atccttctat cttttcactt ataccaccaa ctacttgtat atcacccttt
    13621 tgatttatag aacctgtaac agcaatattt tgtttaattg atactccact aagagatgat
    13681 aatagtacat ataattctgc agaagatgca ctatctccat ctattccacc ataattttgt
    13741 tcaaaacaaa catatgcatt tagtgacaat agtaaatcct gtgcaaaatt ctcagaaaga
    13801 tagccaccta atataagtac tcctttgtta tgtatagagc cactcatatt tacttctctt
    13861 tctatattta ctatgccttt acttcctggg ctagtggtcg ctgtaatcct tgaagctcta
    13921 ccaaaagagt attctcctgt acttaagact gacaaaccat ttatcactcc tacttttctt
    13981 ccctctgttt ctattagagt aaatccattt tcaattgatt catccatatg tgtttccact
    14041 ctattgattc tttttctctt ttcacttatt gcttttttaa catcacactg ctttgtatac
    14101 tccgaatttc taaactctgc ataagcactt ccttctatta caacttccat tattttatta
    14161 aacttagttg ataatttttc taaatcacca gataatctag tgctaaattt aataacctct
    14221 tcaactgctg atttagtaaa atgccttaaa ttattcttat cacattggta tgctataaat
    14281 cttgctattc cttcttcatt atcttcattt ttatccattt cactatcaaa gtctacaaat
    14341 actttaaaat atttttcaaa atcttcatca tatctatata aaatatcata tatatagtgg
    14401 cttccaatca gtactaattt aacatccaat ggcatatttt ctggtttaat tgctgtttgt
    14461 gtttccaata ttactttttt agtctgcaaa gtctttttaa gaatttccca agacattgta
    14521 tattttagta attggtctgc ataaagtact aaataaccac cattagccct atgaaatgct
    14581 cctgataata gttttgtgaa atcagtcttt atatttccat ttgcataatc atactctgcc
    14641 tttccaaata gatttgctgg acttgggttt atctctacta caacaggtgc tgattcttta
    14701 ttctttgagc ttccattgtc tacaaatagg ttaattttat atttaataaa atgctcttta
    14761 tcatacttat cttttaactc ctcttcatct aaatagaata aatacatata ttctattata
    14821 tctttcttta tattttccag ataagtttga atcttatcat aattttcata tttttcacac
    14881 aatctcttga tatgaggttc tactacaagt ttagctatct cttcttcaag ctctaacact
    14941 gctttttcag ctatttcttc taagtttcta attttatata cgacctgtat cgccatattt
    15001 tctagttctc ttttagcttt gtaaaactct tcatcagact catcactttc atcttcctct
    15061 tctttcaaag ggataaaaac tattcccatt ttactctgtt ttaatttaaa tcctttttct
    15121 tctccatatt ttttaatttg cttcaaaagc atatcttttt ctatttcata ttcatccaga
    15181 agtttatttt tttctatttc aaaattttca ctttcaaacg catttttaaa atcttctaaa
    15241 agactttcaa ttaatttctc catatctttc ttaagttctc ttccaaaccc cttttctaat
    15301 tcaactataa taggctctct agggttttca aaattatata tataacacca atctttatgc
    15361 gtattttttt tggatgcata ctcatttaaa acctttaagg cataagtact tttaccagtt
    15421 ccaggttcac cagctatata tatgttgtac gctggattat ttattttcaa ccctaattcc
    15481 atagcttcta cagctctttc ttgacccaat atataatcta gtggatttat ttcagatgta
    15541 ttattatatt tcaatattcc cccacctccc catatttaac tttaatgata taatatgact
    15601 tttacacaac aagtgttaaa gtaaatacac attaaagtat atgaaacaga ctcttattat
    15661 tagtcatcat acttatctaa aattatttcc atatttctct ttattatatt tctacctctc
    15721 cagctaaaag ctctatctcc atatctcctt ttaaattctt tatttgaaat attttgtatc
    15781 tcatcataat ccaaataatc tattatattt tctttaaatt ccaaaatatg agttgttggt
    15841 atttcaacat tatgtggaca tacttcttga caaatatcgc atccaaatac ctttttgcca
    15901 ttctttaaaa caactttttc tttctctgac aaatctcctt ttttttgagt tatatatgat
    15961 aaacattttt tggggttcat atcataattt cccaatatag catttcccgg acaatatttt
    16021 acacacttac cacatttaaa acaacttttt tctagtggtt tatcttcttc aaatttataa
    16081 ttatttacta tataccctat aaatacgtaa gaaccatatt catcagttat gatattatta
    16141 tttattccaa aatatcctat tcctgataaa taagctaaat acctgtcaac taatggtcca
    16201 ttatcagcaa ataacttgta tttaaaatct gttactgttt tagaaatata atcacaaatt
    16261 tgttgtaaaa agtcctttac tacaatgtga taatcctttc catgacaata ttttgataaa
    16321 tttgaatttt tattcttttc ttgtctattt atatgatatg gaaatgcaca gactattata
    16381 gagttagcat ccttcattat atgtcttggg ttaattctgc tctcaattat tggttcttcc
    16441 ataccagtta aataaccttt ttgttgtctg ttcttaagta tcttttctaa attatcatat
    16501 ttatctaccc ctgctactcc tacacagttt aatcctatta aattacaaaa tgcttttaat
    16561 tccttattat ccataaaatt attccttttt aatctaattg actttttaaa tttatttaat
    16621 ttttttagtc tttttaacct tttctagcta ctaactcttt taaatactta atctttttag
    16681 ctattcaatt ttcttacctg cttaactctt ttagatactt cgtcttttta tctatttaat
    16741 ttttttacct actaactctt ttaggtactt cgtcttttta cctatttaat tttttaccta
    16801 ctaactcttt tagatacttc atctttttac ctatttagtt ttttacctac taactctttt
    16861 agatacttca tcttttttat ttacttattt aactttttta cctactaact cttttagata
    16921 cttagccttt ttcatttact tatttaactt ttttacctac ttaactcttt tagatactta
    16981 gcctttttaa tctattcaac cttttttacc cacttaacct tcttaccttt taatataaac
    17041 tctaaaactt caaatatcat tagttatatt ttgacattct ttctatagtt aagcaaaaag
    17101 attgattttt tcttataatt aatatcccat ttacattgcc atttattaag tctttacttg
    17161 acttatatgg atttcttttt actctcttta ctaaacttat acttattaat attatgaagg
    17221 tcttataata gtctaatatg aatatgccca tcatatatca aattttaaaa tttgtaagca
    17281 aaatacttat cttatattac tacatctaaa gtggaaaatt ttacaaacaa gctctgtaaa
    17341 aacactttaa ataacaattt gcttttaaat catatacaga ttataataaa tactgtataa
    17401 ggatggtgaa aaatttgatt aaaataacaa ttccaggtag acctattagt aaatctaatt
    17461 ttaagcttca taacataaat ggtcaagcat ggatgccttc aaagggaaaa tattctaagt
    17521 atcttgcata cgaaaacatg attgcaggtt ttataaacca acagtatcaa ggggaaactg
    17581 ttgaagaaaa tctaataaca gtcttgaaat tattcttccc aaataagaga atgggggatt
    17641 tacataatta tccaaaaagt atttgtgatg gtattgaaaa aagtggaata ataaaaaatg
    17701 ataaacaact taagccagta cttttatttg attttataga taaagataac cctagggttg
    17761 aaattgaact ttatccagta tctaaatacg atatatccta taatattttt gaaaaataaa
    17821 gattttatgt gttattcgac attatattga tactccagta tttgaaacta tactaataca
    17881 acaataataa ttgtgttatg tctatactca aacaaatgtt tttaaaaagc attaagtaaa
    17941 tatttaataa gtattaaaca aatattaaat ttatataata gctataacta tgtaaattta
    18001 atatttgtat ataagaccac atctaataaa aagaaatcgg agtaaattta atacaccgat
    18061 ttcaataaat aaaatctatc ctagcttttc aacaacagtc ttaagcattt ctcttatagg
    18121 aagttcatat ggacatctac tctcgcaaag cccacagtca atacactcag taggtttaac
    18181 atccataacc tcatattttt ctttagccca ctcttttaat ccatatctag tataataacc
    18241 ttcacataaa aaactcaatg gtatatttat tcctacagca caaggcatac aatattcgca
    18301 tcttctacag aattttttac ctaaagaatt tcttatttct tcaatttcct tattatcttt
    18361 ttcatctagc acaagatttt caagtacagc gacattttgt ctaacctgtt caacactctc
    18421 catacctggt ataactacat ctatgtaatc tttagatagt atatatttaa tagccagtgt
    18481 tgcattgtct aaagcacctc cagctaaagg tttcattact attatcccaa ttcctttttc
    18541 atgagctttt ttaaacactt catctgcttg tccttcaact atattgtaag ggaattgtat
    18601 agtgtcaaat tttccatctt ctatagcttt ttctatagta tttaaattgt gactagttat
    18661 accaatatgt tttatcttac cttgctcctt tgcctctaaa agggcactat aagccatttt
    18721 atctttaaaa agattatcat actcctcttc tttaacatta tggaattgat ataaatctat
    18781 aaaatcagtt ttaaaattat ttaaacttat ttcaacatct ctcttcattg aatcataatc
    18841 tctggacata cttttagtag ctaagaaaaa tttatctctt tttccttcaa tggcaattcc
    18901 gattgcttcc tcacttattg tataccctct tgcactatca ataaagttta ttccttgttt
    18961 ttctaactca tttataacta agttagtatc atcttgagta atcctttgta ttggaatgcc
    19021 cccaaagcca actctcttta ttttcatgtt agtattgcct aaatttctca tatctttccc
    19081 cacctaactt ttaataattt tttatataat ataaatatgt catctttaat tatacaacaa
    19141 attatgagaa tctttgcaat atatttacat actattcata gtataattat attttatatc
    19201 agtctattca taatataatc atactttata cccagttaat ttgtatacaa tttttgttat
    19261 tcctatccat taatttaaat tatcacattt catgattgta tctccaccct aattatgttg
    19321 agggtgaagt atttcacata tttttaataa aggtttattt actagatagt atttctttta
    19381 tcattttaag ctctttcttg tgaccttcat catcaaaagg agtttctaag aaaaatggta
    19441 aatgttttag actaggatgt tccataaaat caattaatgc ttttaatcct atctttcctt
    19501 cccctatagg agcatgtctg tcttttttat ctccaaatgg catcatacta tcatttagat
    19561 ggacagtttt caatctttct atgcctataa ccttatcaaa ttcttccaaa accccatcta
    19621 aatcattcac tatatcataa ccagctgaaa aaatatgaca tgtatcaaga cacacaccta
    19681 ttttttcttt atgctcaatt ttgtctatta tactttttaa ttgctcaaat ttaaaaccta
    19741 tttcagttcc ctttcccgac atagtttcaa gaagtatagt tatattttca tcacccttta
    19801 tggcattgtt caatcctttt actattctat ctatgccaaa atctacacca ccacctacat
    19861 gacttccagg atgaaaacac atgtattcaa ttcctaatga gtccatcctt cttatatcct
    19921 catctatcac ccttgttgca aattcgtata catcatcctt tgtaccaccc agattcatag
    19981 tatatggtgc atgtgcaagc agtggtgcaa aattattttc ttttctaatt tcttgaaatt
    20041 taattatatc tttttcatca aattctttag catttcctcc tcttggattt ctactaaaaa
    20101 attgaaatgt atttgcacca atatatacag ctgtctcagc cgcattagca aatccttttg
    20161 ctattgaaag atgtgttcct aatttaatca tattaatctc cttttatttg tactactact
    20221 tgtactcaat tttaattttg aactactcca ccttaactac atttagccaa catatgaaga
    20281 tggagattcc tatttgatag tactttttca ctaaaaattc gtaagctcta agggatgttc
    20341 tatcccaact aatctcagtc ctcttttaac atatttctag cattgattta atttatatta
    20401 atttttaatt ttaatattta cactttaatt atacccattt taatcaattt caaatattat
    20461 aatcttacat actttgtata ttatctaagc acttcttaga tagtgtatac atcttacact
    20521 atacatatta tttacaaata caataggtat aaaaaaacaa aaaaatagag attaaaaatc
    20581 attgttttac ccataccaaa aactattttt tgattattaa gtaaattttg atgttcaatc
    20641 tctaatatta tatctttaat taatccataa ttaattctct aactaggaca ttcctcctca
    20701 agagtaggaa ctataaccat agctatatca tacttagaac cttcaacatt gtgttgtctt
    20761 ttatttaaaa tttcatctat ctttgacttc atagtgtcac taagttcaac taattcatca
    20821 tgagtaagag aaatatcatg ataatcaact atattttcat tttctaaaac atcttcctct
    20881 gctgccttat aaaaaacttc actcatattt tcaaattttg atatgtacaa ttcttctttt
    20941 tcttccccat tgtctaaaga aaaattaagt atcctattcc ctataaccac attttttgca
    21001 cttggataat agtacttttc cacaatcccc gactttattt tttcctcaac taattctaaa
    21061 ataccaactt tgtataacat ttttatatgg tagtttattt ttgcatgagg ttcttccaat
    21121 aattgagata attgttttgc tgacaatggc gatttgtcaa atgcttttag aatatctatt
    21181 ctacgtggat gcgcaatagc ctttatgcac tccaaatctc gtaataccaa tacctctttc
    21241 attgacccct cctaaaaaat ttatttaatt catatttctt tacaatttaa ttatatatta
    21301 aattatatgt tgttgtcaaa aaaatccttt cttaatattt taaaaaatat ttaatttgag
    21361 tttatttgac aactcctcta aaactttaac tcctgcgacg ctgttacctt ttttgtcaag
    21421 cgcaggtcca taaacaccaa tccccatgcg tcccggcaca gaagccatta taccaccccc
    21481 aactccagat tttgcaggaa tgccaacttt aatagcaaat tccccagaag catcatacat
    21541 tccacaagtc atcataaatg tcttgacaat cctagaaacc atttcactca ttaaatgctc
    21601 accattttct atatctactc cataatttgc aagatttatt ccaattctcg ctaaatctac
    21661 agaatctatc tcaattgagc attgtttaaa ataaaggtct agaacatctt ctacattccc
    21721 tctgataaat ccatcacttt tcaataagta agccatagct ctgtttctat ctccagtcat
    21781 tttttcagac ttatagacat catagtttat tcctatatta tcattttttg ctaactttct
    21841 aaagaaacta agcattcttt cttctttttc ttctaaacaa ctcccattta taagggaagt
    21901 ggttactata gcccctgcat ttatcattgg attacagggt ttttttgtgt cattaatttc
    21961 aagtttcatt attgaattaa atgggtcccc acttggctcc attccaacgt ttgaaaaaac
    22021 gtcttcccaa tcattatcca taagtgccat agcaagcaca attggttttg aaatactttg
    22081 tatagtaaac tttgtgctac agtttccagc actataaaga ttattttcgc tatctatgat
    22141 acaaattcct aaatcatttc ttctagcgtt ttttaattct gggatgtaac tagcgacttg
    22201 tccataatta gtatacttct tattagaact tataatttct tttaataatg tctcatctaa
    22261 cgtattcata tgcacctctt atattatgtt atatattcta ttttagcaca agtttatact
    22321 ataataaaac aatgttaaaa aaaattatac tttaaaatta ttttctacaa gaatcaattc
    22381 atttttcaaa caatttaaat agtttaaaga gcttaataat ttagtaattc aataatttaa
    22441 caacctagta atttagcaat ccagcaatct aataatccag taatttaaat ttttataaca
    22501 ccaaaaattt ctaacccaac accttttact cttttactct tttactcttt tactctttta
    22561 ctcttttact cttttactct tttactcttt tactctttta aaaaataatc acataaacta
    22621 acaaaatatt aaacaaaaaa gtaaaattta aaataaaaag cttgcttcat acaaaagtat
    22681 aaaacaagcc tttttatata tcaactcaaa ctttaaaatc tgtatcaatt taattctcca
    22741 ctttacactt aatatactta acataaacca ataacactac ttgctatgcc atttaatctt
    22801 cataaaacaa tctataatac acacattaat caactatttt acttcctcca ataaattccc
    22861 taagaattga aatacctggt atgtcagaag tatcgtccaa ttcaacaaaa tactgcaaaa
    22921 actttagtaa tctagtagct tcaatatgtg caggattatc ttcctttatc tcttccaaca
    22981 aaggtttcgc aaatcgtttt aaaactgcca attcatatac acaagcagag ttaaatatag
    23041 catctgcctc ctcttggtac gggaatatat tcttcttttc tcctcttcta actgatgccc
    23101 attgtaaaat agtattatca gcactatatc ctctaaaatt atagtctcta acaattcttc
    23161 ttatcattct caaatcagca gtagggattc gattatggtc atccaaattt atttgagtaa
    23221 gggcacttat gtatatctta aatttatctt catctggtat agatgatgtt aaaataggat
    23281 ttagcccatg tataccttct aatataattg gctgatttga atctatcttt atctttttac
    23341 cagtgtattc tctcttacct tctttaaaat tgaatcttat atcatcaatt tcttcaccag
    23401 ctaaaagttt ctttaagtct aagttaaact tctctaaatc tattgcataa attgattcaa
    23461 aatcataatt tccatattca tctaaaggag tatgttttct atctataaaa taatcatcta
    23521 aagaaattga aataggattt aaattattta ctctaagatg tattgataat ctgtgagcaa
    23581 aacttgtttt tccagatgaa gatggagctg ctattaaaac tactctctta ttgccatcct
    23641 ttatcatatc cgctatttga gatagcttct tttcatgcaa tgcttcaaat gtccttatta
    23701 tatctccata ttcattgttt tctattattt tattaagaga tactaccttg tcaattccca
    23761 taagtcttga ccattcttct gcttcataat atacacttga tagcttaggt tgaggtacaa
    23821 atttcatagg aagagtctta tcttcttcac taggtcctaa aattataacg cctccattat
    23881 aaagcttaat atcaaatgat tttatataac cagttgatgg caacatataa ccataaaaat
    23941 ggtctatata gtttctacac ttatatactt tagcactatc atactctttg tatttcaaaa
    24001 gctctgcctt ttcatacatt tcattatttt caaagataga aatagcttca tttcttgtaa
    24061 cttcaatttt ttctataaca taatcgttgt ttactatctc tttcatcttg ttttttatat
    24121 tttcaacatc tgcttcttta agctttctat ctatatgaac ttcacaatat agcccatctg
    24181 atagtgaatg ttctattgta actctgctat cccaaaagat ttctctacat gccattacaa
    24241 atataaatga catgactcta aagtaaactc tctctccatc ttcattagta gtatctaaaa
    24301 aatttatctc acaatccttc ttaactctac aatttagctc ttttagttta ttgtctacaa
    24361 ctgcaagtgt tatataaccc ttatgctcat cacaaaattc ttttgctata tctcccaatc
    24421 tgattccagg ggaattttct tctaatgaat attccttatc ttttccttct atttttaagt
    24481 ttattttttt cacttcaaca tctccttcct tttgatgaat ataaatttta attaatgagg
    24541 catatcaaca agataaagag aggtatttaa ccctctccta caatattatt caatttactt
    24601 atagtatctt caatgtcttc gtaatttatt tctaatacta aatattctgc atctaatgtt
    24661 aagacctctt taatcccctc ttcagataaa attcctcttc ctataccaac atgtgtatca
    24721 ttgataccat cattatcact taagtgtatc agtcttattt tatcctttaa gttctttaca
    24781 taagcatcct catcaattaa acagtgtcca gtatcgtaac aaaaacaaat cttagaattt
    24841 ttaatcctct taaatatata ttcaaaatca taagatatat ttccaatatt tgaaaaatcc
    24901 ccaccttttg aataagtatt ctctatacat acatatgaat ttgtatttaa tttatctaaa
    24961 aaatccacac tatttcctaa atatttgtct ctattctttc taactctatt tgtcataaca
    25021 tatcccaaat gaaggttaaa ataccttaaa tcaaatcctt ttagttcaaa ttctatcttc
    25081 tcaataaaat ttatccatga atttcgtata tactctatgt tttcgcaagt atttaattcc
    25141 ataggcaagt gtatccctat agataatcct aacttagaaa ttctctcttt atatttacat
    25201 aactcactac attcagatat attgtcaatt ccaatctcta aatgagttat ttgctttata
    25261 ctctcacaaa tgtttaaagc ctcctcaata ttaaacaata aggacgctat accaactgcc
    25321 atacaaatca cctactcaaa aatacctata tctgtaaaag gaaatactct taaaataact
    25381 tttcctttaa tattttcttc atctactaat cccacttctt tatatctact gtctaaacta
    25441 acttctctat tgtctcccat cgcaaatact tttcccttag gaatcaccat atcaatatcg
    25501 ccttcagtat aattatcatg tatatatgaa acttcattta ataacttacc atttatataa
    25561 accttagaat ccttaatttt tagatggtca ccaggaacac ctataaccct ttttacaagc
    25621 tcttttttcc ttccattctc ttgtaataaa tcagtcttaa atatcattat atctccacat
    25681 tttggttctg ataacttata tgtcatcctg tttgctacca aataatcatg tgatttaagt
    25741 gttgggtaca ttgattctcc atttactaat gttggtttta taaaacgagt tataataaat
    25801 gcaaaaaaaa gtgcagtaat aattattttt atccactcta caatctcttc tttaatagtt
    25861 tcattcattc acaaattctc ctttatagtt atattatctt tattgataat gtctcttaaa
    25921 cactatcttt tagataagtc tactaaataa ggtgttgtct tttttatata gacaactatt
    25981 gtgtatggtc tggtgatttc agctaatcag cgattgctcc aaattttata tgtttagtca
    26041 atagttccta tcttagaaaa tggatacaat ctgactagaa cctttcctaa aatggtatgc
    26101 tcgtcgacca atccaacctc atcgtatcta ctatctaaac ttttttctct attatctccc
    26161 attgcaaata attttccttc tggaactacg atatcaatat ctccatcagt acgattatta
    26221 tgtatatagg aagtctcatc taacaactta tcatttacat ataccttgga gtcttgtatt
    26281 tttacatggt caccaggaac acctataact ctttttacta aatctttttt ctttccattt
    26341 tcctctgtta agtcggtttt gaatactatt atatctttgt attttggctc tcctaccttg
    26401 tacgcaattc tgttaactat caaataatca cgttcaacta atgtaggata cattgattct
    26461 cctttgacta ttgttggcac tataaaacga gttattgcaa atgccaaaac aagagctatg
    26521 acaatcactt ttatccattc tacaacttct tttttaactg cttcacccac taaaatcgtc
    26581 tcctctgtgt taaatattaa gtcaatctac agcaaaataa tctaccataa acctacaata
    26641 taaatattat acttcttttt tctaatagtt taaaatactt ttctaagacc tttaggataa
    26701 tgattcttaa ttacaccaga agattctttt ccccaaccta aaggtattcc ttcaaccgaa
    26761 accaaaaccc atcctctact atcattagaa tttacaacat ccccttttaa atatttaaga
    26821 attgattcac tctgtacact gaagttttca acatttttta catcttcaac ttttaagtaa
    26881 tgagatagtg catgagaagg ctcaaatcta ttcttcttta aaacccctaa atgcaaacca
    26941 tatctcaata cttttagttt tttcgtatct ggatatattt caggaagtag gtacaaattt
    27001 tctcctctta aataaaattt atttttttta ttactataaa aatcaacctt taaaaatttc
    27061 ttttcaaact ccctataatc ctttatttct ttatctaaat tttttatttt taattctttg
    27121 acattacatt cttcttcttc taattttttt attttggcaa caaaatgacc ttctcccttt
    27181 atcttatgag gccataatct ttccatttca ataagttctg catgtggata ttcactgata
    27241 aactcattta taacatgctc attttcctcc cttgaaaaag tacaagttga gtaaattaaa
    27301 atgccatcct tctttaacat tttatatcca tctcttataa tctctttttg gatggattga
    27361 cattctacta cctttgcata actccaatct gatatggcaa cctcatcctt cctaaacata
    27421 ccttgcccag aacaaggtgc atctataata accttatcaa aatacccatt aaacgtcttt
    27481 cttaagctat tagaatcggt gtttgttata atacaatttc tcgctccaaa tcgctctaaa
    27541 ttttccccta gagccttaat tctactagca ttaatttcat tagaaaccaa taaacctgta
    27601 tcgtttagct tagatagtat atatgtagat tttccaccag gagcagcaca catatcgaga
    27661 actttttcac cctctttaat atctgccttt ggtattacac tcattgcaga aggctcttgc
    27721 aaatagtatg ctccagcctc atgcagtgga tttctaccag gtctgtcaat tttatcatca
    27781 taataaaaac cttcttctgc ccatggtatt tgattcaaat caaacaactc caaatcaaat
    27841 aattttttct tgtcaatttt taaagtattt attctaagcc cagtagtctt actttcctca
    27901 taacttttta taaaatcatc atattcatct tttagtattt cttcaatatc ttctaaaaat
    27961 tcatttggta attctgtcaa atctataatc ccccttcaat ctgctttact tgtgtgtcat
    28021 ttattatact ttaattattt atgtctttcc tttaaatttt atttcttctt ctttttccta
    28081 agattaccga aaaacacttt tttagagtga ttcatatatt tctcaagttt atcaagattt
    28141 atcttccaca aaattattac ataaactata agtaatataa tagcccatct atattctatc
    28201 atcaatatga aatcaaaaac tccatgtaat aaaattggaa ttaacactgc cataaacaaa
    28261 tactcacgtc ttttattttt atttccctca aatttatact tagaaatata gtagcccata
    28321 gtaattgcaa acattacatg agctggtata gagataactg ccctattaat accaacttgc
    28381 agtgctagat ttctactttc agaaaaaata taaaccatat tttcaattgt tgcaaatcct
    28441 aaagctaaaa atacagagta aataatacca tctaactttt cagtaaagtg tttttcttta
    28501 attagggcag gaatcagtat cagagctttt acaccttctt ctacaagtcc tgcaactaca
    28561 aatgatacat atattagttc tgaataccct tcaaatacat taaacttcat cagtaaattt
    28621 tctaaaagta taattataac acttagaaaa gcacctatta aaaaaaattt aattagatgg
    28681 attaggggtt ctctacaata tctatcttta gaccttatcc aaaacattcc tatcaatata
    28741 ggaactattg ctaataaaaa taaatctagc ttcatagatt attttccttt caaaattttt
    28801 gatttattta tgatttatat catctactta tttttaactt attcgtgttt taaatacata
    28861 ctaaaatata cattaaatta ttttaaatta tttaaataca aatatactca aatactcaaa
    28921 aaaatttaaa tttatatcta tattatttaa caaattttaa gctatattca tatcttgaaa
    28981 tataagggaa ctaaattcat ttaaagaaag ggtgatttga tgcaagatgg tttcttaaca
    29041 gtaagcataa ttgatgctac taacaataga cctattcaaa atgcagtagt aaacatatat
    29101 tcaatgtcta atggtagcca aagctcatca actttatacc aaaacctaag aagtaatgaa
    29161 tctggtcaag tgactggttt agtattacca gcaccagatg tagattactc tctacaacca
    29221 tctgatgtta gaccttatag ccagtatata gtggaagcca tagcagatgg atatgagaca
    29281 gttgtcatag aaggaacaca gttgttagct acaattgaag caagacaagg agttcccatg
    29341 tctcctagaa caagaagtaa gcgttctttc tcaagacaaa gtgagttgat ttttgacata
    29401 ggagaacata ctctatatgg tacttatcct cctaagattc cagaaagtaa cttaaaacca
    29461 ttaccacctc ctactggttt cgttgtatta gataaccctg tagtgcctga atttatagta
    29521 gttcatgatg gtttgccaga agattcatca gctccaaact attggattcc atttaaagag
    29581 tacattaaaa acatagcatc atctgaaata tattcaactt ggcctgaaca gacaatttat
    29641 gcaaatgtaa tagctataat atcatttact ttaaatagag tctttactga atggtataga
    29701 aataaaggat ataactttac aataacttca acaacagcat acgaccataa gtttataaat
    29761 aatagaaact tatttgaacc aattaacgta gttgtagatg ctatttttaa tacttttata
    29821 aaaagacctc ctacatcaag acagccacta ttagcacaat attgtgatgg acaaaaatcc
    29881 caatgtcctg accaaatgac tcaatggggc agtaaagact taggtgacca aggatatgac
    29941 tatgagagta tactaagata tttctatgga gatgagatag tatttgaaag agcgcctata
    30001 gtaagtggtg taccagtgtc attccctggt actacactac aagttggttc ttctggacag
    30061 tatgttagaa ccatacaaaa tcagttaaat gctatatcta attcttatcc agctgtacca
    30121 aaagttatag aagatggtat ctatggaaca gatacagaaa acgctgttaa gatattccaa
    30181 ggaatctttg gtttacctca aagcggagta gtagatttta aaacatggta tgaaatatcc
    30241 agagtttatg tagctacaac tagaatagct tctttaaatc ctttaattta aagcttgatt
    30301 tagaacataa actcaaatta ttgaataaaa ttattaattt aaaataaaaa tggctgttat
    30361 gaactaatat ataccataag tattacttat aagtattgta gtcttaacag ccatttttta
    30421 gttataactt gtttttttag aatcttaaaa ctttaaatgg gggattttaa gcttcttaaa
    30481 aacagtgctt agcaacttag atttctttaa aatattatat ttatttttaa gtttaataaa
    30541 atgctattct aacgaaaaac ctacttttta tttaaaatct cacttattat ttaaaatgct
    30601 acttctcact tagagtatta ctccttatta tttaaaacac tatctatcac ttagagtatt
    30661 acttcttatt atttaaaaca ctatccatca cttagaatat tacttcttat ataaattatt
    30721 atttattata aatacaaata atattaattt aaaaagttat tcctaattta aataatacta
    30781 ctatcttcat cagtgaacct aaactgcaac tttagactta ttagctaaag ccaatattag
    30841 acctaaagct atagatgcaa atgcagaagc aattactcta tactcagcag ggaataagaa
    30901 tacaattgta tgacatggta tccagaaaaa tggtatagtt tttaaaacac taaaaccaag
    30961 gtaagcattc cagtccacaa tatttaccac atctttaagt tttaccttaa tcccctttcc
    31021 aacctcatat tttttatcta taaaacagtc cataacctta tggaataaaa atacagttgg
    31081 tgacattagt atattcatag ttgcactctt aaatagagca tttgcaaaag ctattccctc
    31141 aaatggaagc ataccatcca cttgtgcttg acctacacct gatgagtaga ttgacattcc
    31201 atatgtggta actacaccta ttattcccca aactattgct ctataaaata ctcctactgg
    31261 tattttccaa tccttataca aaattctagc accaagtaaa tctcccattg tagctaatac
    31321 agcaaacttt aaaaaacctc caatatatgg atgtgcacct gttgcttcca taaatacttc
    31381 tctactactt ggtattgcta agacagcaat aatacaaata agaactccac tccatataaa
    31441 atcgcctttt ttcatattta taaatactat ttaatatata aatagttctc ctttctatta
    31501 aagatttatt taatttacaa tctatctaca attatttatt aatcacttat tattagatat
    31561 tcattttcca tatttaaatt tattctatcc ctttatctat ttattttctt actactctat
    31621 ccaccattat ctatatattt attttacgat tactctttca ccctaaccct ttaattatct
    31681 attttttctg atattcttat ctaccatcat ccatatattt attttacgat tactctttca
    31741 ccctaaccct ttaattatct attttttctg atattcttat ctaccatcat ccatatattt
    31801 attttacgat tactctttca ccctaaccct ttaactatct attttttctt actattctta
    31861 tccacatcat ccatatattt attttacgat tactctttca ctctaaccct ttaactatct
    31921 attttttctg atattcttat ccaccatcac ccatatattt attttacaat tactctttta
    31981 ccctaaccct ttaactatct atttttttct ggtattctta tctactatta tctgtatatt
    32041 tattttatga ttactctttt aacctacccc ctatacttta tagtaatatg tttttaacct
    32101 ttttcattat tcccaatatg ctttataact acaaatactc tcccccctta aaaataataa
    32161 taaaattaat caataaattt ataatcatat tattactcta tgtattaagc aattactatg
    32221 ccaataaact ttgatttttt taaacaaatc ttaaaaatcc taaaatgcta attttcttta
    32281 acttttaatg aatctaatag ataacattta attttcgtta tatttttcag aatatttcta
    32341 ttattatttt taagaaaaaa aaataatgtt aacatttctt aacatacatt aaaaaatgtt
    32401 aacattataa attgggttta atacttttac tttgactcga tttactttta ttctacttct
    32461 tactttattt ttaacttaga ctttattttt ttattactta tttgagtctt atttatttta
    32521 ttatcactcc atatgttcaa ttacatttgt ctaaattctt tgatactttt attacataat
    32581 tttaacaagc ttaagtgtta tttgggtagt gcagttgata attatttaaa taatcatcaa
    32641 ctgcatgttt atatcattac agtagcttaa tgtatttaat catacttact taggattttg
    32701 aaatatctta gagattatat ttaacattag tcaattgctg cataattgta agcaattgaa
    32761 atttgagacc catcttcatt ttctatagtg ataggcttca taatttttaa tccttcagtt
    32821 tttatctttt ctaattcttg ttccattttc ttaattgttt cctcaaggtc tttttgactt
    32881 acatctttga ctgcattagg gtctttagca tagtctttta attcttgaat atgtttagca
    32941 tactcttcat aagtataatg ctcaacacca tacttttcca attcagtagg gtcagttatt
    33001 cctgatttta ttagagattc aagtttaggt aaagcaatat tagatgaatc atttccattt
    33061 gcaaatactg ctccagttcc tcctagtacc attgcagata ccatcattgc acttataagg
    33121 gattttttta ttttcataac caatcttcct ttcttagaga tttatttggg tagtgtagtt
    33181 tgaaatgact attgcaatag ttatcaacca catccttaga ctatcacagt agtcatgttt
    33241 atgtcaagcc tttttaaaaa acttttcaat aaaaaatact atctcaaaac aaaattaatt
    33301 attttgagat agtattttaa ttctaaatct tttatattac taagatttat ggttactcta
    33361 tccatgttct atattgttct ttattaactg ctaacaaatt cccttttctt gatatgacaa
    33421 agcgattatc attatagcca ctttgctcaa ttgaaacttc tcctgaatca gtataaagta
    33481 catccttacc attactagat ttatttacat acgtttcttc gctattctca gaattagtta
    33541 ctttgctcat agatgattct tcatgctctc taaattcaat tacagatact tttgccgtac
    33601 taaaatgagt ctctccatca cttttagctt tactaacaag aatatcagat tctactttgg
    33661 gagaatataa atcagttgat ttactactta ttgaaaatcc aattttatca ctttgttcat
    33721 tttttgttaa accaaaagat tcaacctcat taatctcttt attttctgtt gcaaaaacaa
    33781 gacctgtccc acaaactaat acagttgaaa ctaaaaaagt aacataagtt gattttttaa
    33841 atttcataat attaactatt ctcttttcta tttttgtctt tccaaatcca ctacatattg
    33901 tcattgaaaa tggattattc tcctctgcta gacttattag tgtggttgca taatcagccc
    33961 tatattcttc accaagtata ctcataacct tttcatcaca actaaattct atgtctttat
    34021 ttagtaaaaa aaacatcacc caaactaagg gattaaacca atggacaaca agagctacaa
    34081 gcataaataa ctttaacaga ttatcaaagc tattaatatg aaccatttca tgagttaaaa
    34141 caaagtctaa agtttgatta ttagcataat tcatttgctt tggcaaaata attcgtggtt
    34201 ttaaaatacc agatgtaagt ggtgtcctag taaattcaga tatgcaaaca ataaatcttc
    34261 taaaacggct attcttacac atccattttt taatgaactc atgatttttt atatgaattg
    34321 aagttttaaa aagattaatt attttaaaat atctaaagca taaaagtatg ctaaacataa
    34381 tagtaactat aaaagacaaa atgcccaaca tttccaacat cataatattt tcaatattag
    34441 acattatttc aaattcgtca gaattgtttt tacctgtaga gtcactagct ttcttaagag
    34501 tataattttc tgttgatgta ttacccaatt ccacatcaaa agtcgattca attatactat
    34561 aaatactaaa accagaattt aaacttactg gtattagaag tttaaataaa acaatcaacc
    34621 acaataatac aaataccttt ttaggtaatt ttttaaataa acatgctctt ataaaaataa
    34681 ctattaaaag taatactcca gaagtaaaac tcatttctaa caatttaatg aacataaatc
    34741 ttacctcact ttaatttttc aacaatttgt ttaagttttg taatctcatc acttgaaaga
    34801 ttttctttat taataaaagc tgaaagaaat ttttctgaag accctccaaa cattttatta
    34861 attaaagttt ctgtttcctg tttttgtact tcctctttgc ttattaaagc tttacaaaca
    34921 aaattcggct caattctctc tattgcacct tttgacacta atttttttat aacggtatac
    34981 gtagtgtttc tattccatcc tgtttcttct tttaaaattt ttactaactc tccagccttg
    35041 ctttctcctc tctcccatag aacttccatt actttaagtt ctgaatcaaa taattttatc
    35101 tccatataaa atcgctcctc aaatatagtt atcacaatag tcattactat aataaaaaac
    35161 tatcatagta gtctatacta tgtcaatcat ttatttttta ataataaaaa ctgtcttttt
    35221 aaaaaattct tataaaagac agttttatca atgttatact ttaatcttta attaaagcca
    35281 tattttattt aaatatataa ctatatatct tagtacatag tataagattt ttctttatct
    35341 aatagtatat cctctacatc tgggttttct tttactaatt gtctataaaa attacaatta
    35401 gtaacaccta catatggaat tagccatagt agacctattc caagagtagc tattgaaagt
    35461 atataccatc ctataaaact aaagtttagt acaaataatt taagtacatt tcctttcatc
    35521 atatctaaac tagcacccat tgatttaaat acacccatat tatccttgtc ttcacaaatt
    35581 aagaaagtag cttgagaaac atataatagc aatatataaa ccggtaacat aagaacaagt
    35641 attataagaa ctagagttat tccagtagaa ataacagtcc ctattccaac attatcactt
    35701 gataaatatt caattgctcc actagtaagt aaaactccaa atgataaaaa cgctcctata
    35761 attgtgatta taaaagaata aatataaaca ataattgatt caaataaata aaaaccaaaa
    35821 cttcttaaat aaattctccc acttacaaag atatctccta tcttgacttt ttcatcttta
    35881 gtaattttca agaacataca tgtaaatcct gctgaaacgc aaaaagctat tacagccact
    35941 acaatagtag tcaatggttc aaaaggtaat cctacaattg atattaatac tatcaatgca
    36001 atatatactg ccatagaaat tgcacatatc ccccagtttc cagataactg agctttagat
    36061 actcgtttta attcttgcct tgataccata aaaaacaccc ctttcatttt ataaaaaaac
    36121 ttttaaaaat ataaataatc ttttaacgta taatattaat atatcatatt ttcgactata
    36181 taagatacaa ttattcacca tgttttatca agatatacca taattgtatt actagtttta
    36241 tatagtcaac attaccaaat acatcaaata aatttgatta attattcaac aagtaataaa
    36301 ataatttcta ttaattatac tttatttagt aaacaaatta tttaataaaa aaattaccta
    36361 atacagtaaa ttaattggta agataaatta tttattatta gtaaagtaaa ttatttacta
    36421 tttatcaaga taaattattt ataaaataaa tcatttataa aatataattt atactttgaa
    36481 aataaaataa actatcttcc aaacatttta ttatatgctt aaaagatagt tttgtgtctt
    36541 taaaataaat taaattgtat atattccttc acataacttt tgtatattac taggtggttg
    36601 ccatttacca tcttttttag tatatgtaat catagttgta acttccttag ttggtttctt
    36661 attgtaaagg tctataatca tttttgtcat atcatcttga acttcttttt cttttttatc
    36721 gtaattcttt tcatcagtta cataagattt tactaaagtg ttcgcttcac tcattacttt
    36781 actagtatct aaagctttac ttacaacttt caaagttatc ttatccttac tagaagattc
    36841 cactgttact gtcttttcaa caccttgaat taatttaaca attgtttcgt atatcttttc
    36901 agcattttct ttaccataaa gaggtgtcaa ttgagcaatc attgaaacct tgtccttgct
    36961 gttataagtt tgaatctgtt tatattcagc ttctgttaat gcatcagaaa ttcctttttc
    37021 atcatactta tacatttcta atgcagctaa attagcttca aaattcgact ttactttttc
    37081 ttctgcatta gaacacccta tagttagaac taaaactaga gccataatcg tagataatat
    37141 taactttttt accattttca tacaaacatc ctccctcaat taaaataata aaaaatttat
    37201 ttatcaacat tataacataa atttgtctaa ctatagaatt attttgaata ttttaccact
    37261 tccagtctat tccaataccg ttttcttttg ctttatcgta tattcttttt gctgttacga
    37321 catcttgtac acctatccca acagttttaa atacaattat ctcatcatca tcttctcttc
    37381 caggaatagt tccgtttata acattcccta aatcaccact aaaatcatct ttacttatct
    37441 taccttcttt taatggaatt aatatatctc ctgactcaga taaaactgca tctgttgatt
    37501 caaaaaatat cttagacgct ctagttaaac agtttgggca caactcttgc atatctggca
    37561 tatatgaacc tactgcactt attaaagctc cttttttcac taagtttcca ttaagtactg
    37621 gttgttttga tggagtagct aaaactatca catctgcgtt atttatggct tcatcagatg
    37681 attcaactgc aactatttta gtattatatt tacttaattt taagttcatt tcttctgcaa
    37741 atttttctct actttccttg tttctactaa aaactcttac ctcatccaaa tttctagctt
    37801 ctatcatggc ttcaagttgt ggctcacctt gtcctcctag acctatcaaa gctccaatct
    37861 tagaatcttt tttagccaat acgtctatag ctgctccaga ggctgctcca gtacgaatct
    37921 gagttacata agtgccatcc aatactgcac taacttctcc agtttctcca tctaataata
    37981 gtactgttgc tggaattact ggtttgcctt tttgagcatt tttaggaaat acagatacaa
    38041 tttttattcc cccacagcct aattcttcta tgtatcctgg cataaataac atactagcat
    38101 cttgacttgg aacagatata ttggttctca aaggatttac actctttcct tcacaataaa
    38161 ttctaaaagc ttccttatca gcttcaattg catctctcat tgtaaatact ttttttatgt
    38221 cgtctttttt taaaagtagc atttttatac ccccaatttt aataagtctc tatgctaaat
    38281 attatagcat aacatttaat ttaatcttct atttcaaatc aaataaatct acatactctg
    38341 gttttagcat agaacttatc aacgctttat ttattgaaaa ttctggtatt cctgctgcat
    38401 atggagttat atcatataaa tcaaaatata caactagatt ctcatcttgc aaataaaagt
    38461 tttgattctc ttttatacct ttaaaattat atattccgat attttcttca tccttttttt
    38521 caagttcagc tatttgtctt ttaatttctt catctataac ttctttatat ttagtattat
    38581 ccttaaacaa gtccattaat tctaaaaatt ttccagttct catatccaca ttatatgcta
    38641 tatcttgata aaatccatgt gctccaccac tataagtata atatctcact tttatactaa
    38701 gagcagaatc agtattcttt ttaagttcaa agtctacatt tgcaacaaac ttatttttct
    38761 cgtcaggatt atccttaaga tactgctttg cttctttata tgatttatta taaaattcaa
    38821 atatgtcatt ttttatctta tcatttgtag acctttcaac aattttattt gaatttgtta
    38881 ttacaggcat gtttatagta ctttctaaat actcatcatt tttcactatt gttttacttc
    38941 ctattgtact tactgataaa gtttgtttac tatttgtatt accctttggt aatgactggt
    39001 tactcataac agtcactgct tccttattac tatttaaatt aattgaagca tctttcctta
    39061 aattattata tttatagtca tgtttaattg ccaaaacagc cattatagtc aatgttaaaa
    39121 caaatacata tcttaaaact ttagcttttg tatcgacttt aaaaaatttc atattatcat
    39181 tttcctccta aatataaatc tctcttatta tatttggagt ttctagggtt ttttatccat
    39241 ataatttaat aaaagattaa tttttattta taaaaaatta atctttttgt tttaaaatat
    39301 taatatgtct tatcaaacag tttgaaattt caccaagagg taattgtaac ataacagaac
    39361 ctctatcaaa agctaccatt ggcattccat atactataca agaattttca tcctgtccaa
    39421 ttgtaaatga accattttct ttcattttta aaagtccatt tgctccatca taacccatac
    39481 ctgtaagtat tattcctatt gaatttttac ctgctacttc tgctactgaa tcaaacaaaa
    39541 cgtctactga tggacagtga ccacttattc tttctccctt ttcacaagtt acataatatc
    39601 cttgtttatc tgtacacaat ttcatctggt aacccccagg tgcaattaac acatttcctt
    39661 gttcgactct atcattattc ttagcttctc ttacattcat aatacactgc ttgtcaagcc
    39721 gttgtgcata catataagta aatatagctg gcatatgttg aactacaaca atccctggtg
    39781 ttgattttgg taggtctttt ataatttcaa gtattgcttc tgtaccacct acagatgcgc
    39841 ctatagcaat aaccatatta ttaaaacgtt ccacattacc gcctccaaaa aatcatatat
    39901 caaaaatacc tttttatcgt ttatatatag caggttttac atatttgtat ttagtactac
    39961 ttctgttgat tacttctgca tgtcctacaa acaaaaaact atcttttttg gtagcattat
    40021 aaaatttatt tataagttct tctcttgttt ttaaatcaaa ataaatcata acatttctac
    40081 aaaaaatcaa atcaaaatgt tgatatgaga aatcattcat taaattaaac ggcttaaaaa
    40141 ttacactttt tctaatctta tcacaaattt taaatgtacc atccttgttg tctataaaat
    40201 acttcttctt ccataactca ggaacattgt taacatttga ttctatgtat atacctcttt
    40261 tagctttttc aagtgagtta gttgaaatat ctgtggctat gattttaatg ttccacaact
    40321 ctttattata tccaaaataa tcatccaaag tcatagctat tgaatacgct tcttctccac
    40381 tagaacatcc tgcactccat atatttatgt ttcttatttt attattttct tcccaaaaag
    40441 gaagtatact attctgtata aactcaaaat gttgaggttc tctcataaaa aatgtgtggt
    40501 tagtactcaa tctatttatt aggtttatag cttcatttcc tgtcttatct ttaaataata
    40561 gattcatata ttgactaaaa gaactaagtt ttttctctat cattgtattg tataagcgac
    40621 cttcaattaa cgctcttttt ttacttaaat caataccata ttcttttttt acatagttta
    40681 caagaactat aaattcttca tctgtgagtt ttatcatgca aaaacttcct cctgctaatt
    40741 tatcagaact aactatatgc tattaatcaa aaactttcga atatctaaaa ttaatataga
    40801 attatcttca actttcgcaa tctcttttat atctttatta atattagtgt tgttagaatt
    40861 agtcgtctct agtaaattta gattttctat atgaataaca tcaacaactt tatctacaat
    40921 aattccaact tgatactcat caacctttgt aattattata caagttctct cattataatc
    40981 agctttagga agattgtact ttatatgcat attaataact ggtattattc ttcctctcaa
    41041 attaataact ccacttatat atgttggaag acatggtaca tacgttattg attgaaatct
    41101 tatggtttca atcacatttt ctaattctat tccataaata acatcattga cataaaatgt
    41161 taatacttgt ttaataattt catctttagc catactttaa atcccctaat atatttctat
    41221 aatgctatct gcatctataa ttaaacttat acttccatcc ccaagtattg tacatcccga
    41281 taaaccctta ttttttatat taaatcggtt aaaataaact ggaaatggtt tcacaacaac
    41341 ttgctgatta cctattattt catcaacaaa aatgcatact gctttatgct cattttcaat
    41401 aattatcata ttaccattca tcagattggt tacttttgtt tgaatattat atattttatg
    41461 taaccttata atgggaatac atgctccata tattgtaatt aactctgtct tatttccttc
    41521 tgtaattatt tgatttaagt ctgtaagttt aaatgttctt cttatggatg atattggtaa
    41581 agtaaatagt gaatctccaa ctttaaactt cataccctct actatagaaa gagttaatgg
    41641 tatttttata gtaaaggttg tcccttcatc ttgtttactt tttacttcaa ttgaacctcc
    41701 aactttttca atacttttac gaacaatgtc catgcctact cctcttccag aaaattcagt
    41761 tatagattct tttgtagaaa agcctggagt cataatcaaa gaattgacct cgtcatcagt
    41821 atactcatta ctttgatgtt taagaagacc ttgttcctta gcttttgcca aaatcttatc
    41881 tctcataatg cctctaccat catctgaaat acttatcaca gcttctccgc ctagattttc
    41941 agcagataaa actatctttc ccacttcttc tttacctttc gctatacgct cctcaatagg
    42001 ctctattgca tggtccatag catttcttat aaggtgcata aaaggttctg ctaaattatc
    42061 aattacactc ttatctacct ctgtctctgc tcctatagtt attaactcta catttttatc
    42121 taatttttta ttcatatctc gtacaattct atgcattttt tgaaatacac cagcaatttg
    42181 aatcatacgc atagacatta ctatatcttg caattcatct gtaagcttgt gtaattgtct
    42241 tgttgcctta ttgaaattat ctatatcaac acctgtagaa tttacgctat ttacaaccat
    42301 tgattccata attacaattt ctccaactat attttgaagt aagtccaatt tttctaaatt
    42361 tacactcata atactctgct tacttattgg taaatgttca ttttcttcac ttagactatc
    42421 tttttccata tcagtttttt catttaaaac atcttcttgt atctcatctt ctgtatagtt
    42481 attttgataa cttttactta ctttattatt atcttttaat ttattttcta ctgcatcatt
    42541 gtttgatgta tttttcattt ctatttcttt tttactaata tttatgtatt cttttacata
    42601 gagattatct tctatagttt tataaactat tgccttatcc tctttagcta caaattgtat
    42661 ataaaaccca taacttttaa tatactctgt agactctgca tttgtttcta catcttttgg
    42721 ataaaaatct ataaattcac agtaatctct aagttcaaat acaagcatga aagctctcac
    42781 attttccatc atgcaacctt gttcaaagat tatttttact acatcagagt cttctttgta
    42841 ttcaaaattt gaatcgatta cttctttttc gtctttactt tctaaatttg cattatcctt
    42901 tgatttcata gaacttgata attccaaagt actcacatac tcttcaattc cttcaataaa
    42961 attagagtaa tcagaagata tacaacctct tgattgtaac tcatctatat ctcttcttat
    43021 aaaatctaat gattgaaaga ctaaatcaaa taataggtca ttgtctaaaa cttctatttt
    43081 accttcacgt atagcataaa acaagtcttc tacactatgt gctaaagcag atatattgtc
    43141 taaccccatc atagatgctg aaccttttat cgtatgcatt attctaaaag tttcattaat
    43201 gttgttatga gtaaatactt tctctttttc tatttgaatc ataatttcat ctaattgttc
    43261 gagtaataaa cttgtctcaa atataaacat atctaacatt tgtctcatac tcggttcaat
    43321 ataattcaca tttatcacct acgacctaca aataattttc tattatatat gcatctcata
    43381 atttaaatcc ttgatgattc tcttatctca ctatatgtac ctcataattt aaatacacaa
    43441 ttattctctt acttcaatat atatacatct cataatttaa atacatgata attctcttat
    43501 ttcaatatat atacatctca taatttaaat acatgataat tctcttactt caatattcac
    43561 ctcataattt aaacccatga tgattctctt acttcacttt cctttagatg aaatttttct
    43621 actaattctt ttaaaatttg agcttgagca gacatctctt ctgaggctgc tgcactttcc
    43681 tctgctgttg ctgagttcat ttggactact atggaaattt gctctattcc agataaaatc
    43741 tgtgtaattg ctacttcttg actatgtaca gccgaagaaa taccattaat ataattagta
    43801 gttttttcta caccatttac taccaagtcc aatgcatttg cagtctcttt agcaattctg
    43861 acaccatttt ctactgtttt aatagcttct tctatgagaa tagctgtatt ttgagctgct
    43921 tttgcacttt taccagccaa agacctaact tcatctgcta caactgcaaa tcctctacca
    43981 tattgacctg ctcttgctgc ttcaacagct gcatttaatg caagaatatt agtttggaat
    44041 gctatctcat ctattgtttt gattattttt gatatttcac tcgatttttc acttatttca
    44101 cccattgatg tcatcatatc atccatacat ctacttccaa aaccaacttg tgatgcagat
    44161 tggtcagata cctcacatgc aagactagca ctatctgcac acttcttaat tccatctgat
    44221 atctcattaa tcgtggaagc taattcttct actgaactag cttgttcagt agcaccctgt
    44281 gaaagagctt gtgcacctgc tgcaacttgt tctgaagcac ttgcaacttg ctctgctgat
    44341 aaatttattt cagaaaaatc accattaaaa gagtttatta tactttctaa agatatttta
    44401 attgatttaa aatcacctat aaattcttgg tctatctcta ctcttaaatc tccttttgca
    44461 atactagtta atgtactgtc tataaggtct atgtaattta aaagcatact ttgcatcttt
    44521 ttgacagaac tcactaatag ccctatttca gatttacttt cttcaacgtc tatacttgtt
    44581 cttaagtccc cagatgcaat tcttgaaaag tgtttttcta ctttattaat aggaatcact
    44641 atttttaatt ttattactgt atattctatt attgtcaata ttattaaaag ggaaagtata
    44701 aatattgttc ttaatattag actttgtaat tcttttttta cctctacaat tttggaattt
    44761 gaacgggtaa ctatatcctc ttgaaattca tttattaaag aatccatttt ctcttgggag
    44821 tttatatagt cactaccaaa aattatactt tgagctttac tcttatcatt actttcgact
    44881 gcctttattg cactttgttc tgttggtact aaagaatctg atatttcttt tgcttctaag
    44941 attttatttg actcgctctt tgtaagacca attttttcta atttgtttaa agctgattct
    45001 cttgtttttc cgtataattc tttttcataa atatctttat tctttttttc tcctgtaaat
    45061 acatatcttc ttaatacatc acttatctct ctagttgtat cttttatata ctgactttga
    45121 gtcctcaaat tattcatatc attaatactt ttttctactt tttcaaatgc tttataagat
    45181 gaaatagaag aaaaaatccc tgctagaaca gccaatacta taataatcag caatacaatt
    45241 gctaatttag aaagctttac ttctcttttc atatctgtac tccttcataa agtaagttta
    45301 tatctttttt aatcctttca ttgtactcac tacgctacaa tcttttccta agtttttacc
    45361 ctcatacatt gctttatctg ctaaggatat gttttcttct aatgatatat ttgagtttac
    45421 ttctactact cctaatgtaa tagtgcactt tattttatgt tctttatagt tgaaatcaaa
    45481 ctcctttatc tctttacgga ttctttctga aagtatctta gcaccttcta ttggagtatt
    45541 tgtgagcatt atcaaaaact cttctccacc ccatcttgat acagtatcaa tttgtctaca
    45601 attctttttt attatacttg atattactgt taacacgaaa tcccctgctt catgcccata
    45661 agtatcattg ataaccttaa agtcatcaat atcaccaagg ataagggata ttgatgtttc
    45721 actatattta ttaattcttc tttgctccat aagctgatta attatatgtc gcctattgta
    45781 aagacctgta agataatctc ttacaacgag tctattcaat ttttcaagag aagattccag
    45841 ttcattattt atctttttta atttatcttg agatttcttt acttcaagat gagctataac
    45901 acgagctttt aattctgtca tactaaaagg tttcaccata tagtcaattg ctcctacacc
    45961 aaatcctttt actatgtctg tatctgtatt ttttgaagtt ataaaaatta taggtatatc
    46021 tgctgtacga gcattagatt ttacttcctt acaaaactca aaaccagagt tatctggtaa
    46081 aattatatca agcaaaataa tgtctggtat aaattcttca ataaattctt ttgcctctat
    46141 tgcattaaat gcttttttaa ccttaaaatt atcttttgta agtgttttat ctattaagtc
    46201 acacatcaga acactatcat caacgactaa aattgttccc tgttgcttat ttttcatata
    46261 caaacctctc ttaaacataa tatattcaaa ttttaatgat ttaaaatttt tatacttaat
    46321 aattatacca ctatattctt aaatgttctc atcacaatct ttttataata acactccaac
    46381 tacatcccta tgttacatga tagtgcaatc aaacccattg attaattcat ctattaaaac
    46441 ttcatcttta tctgtcaaaa gtttctctaa atctagtaaa gtaattattt taccttctaa
    46501 ttctccaact ccacttacaa aataatccga atattctata gtaactcttg gtggaggtga
    46561 tattttactt ttttctaagc ttactatatc atcaactcta tcaaccacaa atccaactac
    46621 caagtccttt atttcagtta ctactatata catgcaattt gtagtcatta attcatcttt
    46681 tttaagtctc aaacgcatgt ctattatcgg aatgattttt cctcttagat ttattatgcc
    46741 tttagaatat gtaggtagtt ctggaataaa tataatttct tgatttccag taatttctat
    46801 taccttttca agttcaaccc caaagtcttg ctcatctact ctaaacttta gatacttaat
    46861 tccttcatca attagtccat aatctaaata tgggtcatct ggaaatctca tttaatacct
    46921 ccctcctaaa atacactttc tatgaaatat atattataat ttcttcttac ctttatttat
    46981 tgaatctaca agtaattcac ccgtctcagt gtaaaaacgt attgttctac cataattcat
    47041 acctgtgtcc tcagctaata ttggaatatt taatcctaaa agagtttttt ttactgcctc
    47101 aacattccta tgtcctatac ttgcaattac tgaattgcta cttcctaaaa acatctgagc
    47161 acctccagca atttttgctt ttatatatat tctatttgca cctatattct ccatagattt
    47221 aatgagctca tttattcctg tgtcagcaaa tttacactta ttttcaatgt taatagcatc
    47281 tttactatat ggcaacataa cgtgtaacat tccaccaatt ccagctactt tatctatcaa
    47341 acatactcct acacaagaac caagtgcata agtaactaaa acatttggtc tataggctat
    47401 cttcatatct gcaatgttca ctactatctc tctattcata cttctaatcc caacctcacg
    47461 agtatttctc taagtgagct catttctgga atcatcaaaa tgtgactagt aaaataatta
    47521 tcactcattt taaatttatt ttctataaat aagactttgt caccaacatc tgaaaatctt
    47581 atcataggta catttagaac agctccaacc atatcaatac atatatctgg aattgaaaca
    47641 cttatagtca tgtttaacat agatgcaata gcatttacat atgaacttgc cataatattt
    47701 cctatttcct taattgctga aatttcaatt gcctcaatct catctaaaaa agcttcttct
    47761 ttattaaaaa gagaacttag cataagttga gttattgatt catccaacaa aaacataaac
    47821 attccattga tatcaccttt catatcgagt aaaatacata ctactttgtt ttctggacca
    47881 ccaagcaaat ttgtcgcttc attatattca agtatcttga ccataggtat taatacttct
    47941 acattgctat ttatcatgga tgcaagtgca gtaattgcat tcccagagcc tatattacca
    48001 atttctctaa gagcatctat atgaacatca tcaagttcta aataatttat aatataaacc
    48061 cctcccttta ttattgcatt tatttgcttt tcattgtatt agtgtatatt tacactttta
    48121 ttttaaagca ttatctacaa ctttaactaa tgtttctgtt ttgaagggct tcactataaa
    48181 atctaacgct ccaagtttta tggcttctac aatcatattc tcttgtccta ttgcagagca
    48241 cattacaacc ttagcacttg aatccaactt ttttatttct cttagcacct ctaaaccatc
    48301 tttttttggc attgtaatat caagcaacat caaatcaggc ttttcatatt taaatatatt
    48361 acacgcttct tctccatcat ttgcttctat taaattatta tagccacttt tactcagagc
    48421 ttctttaatt atcattctca taaaaatagc atcatctact atcaaaattt tattttccat
    48481 aaaactaact cctccatatg tacaacaata aacgctttta tcttcagtta ttgtctatac
    48541 tatctgacta tttttcgcta cacaataaat acatttcatt gataaataaa agtaattatt
    48601 tatgccatat tatacttaat tctcttaaca taatttgtca acaaaaaaac ttatatatct
    48661 attgtaatat atgtttggcg ttttgacgag ttattaaaaa tataattgta taaaacataa
    48721 aaagttatca aaagtaatta aattataata aaacaacttt ataccttttt tatgtttgta
    48781 taaaaaaatt tttcagattc attaaaatca tttctgtaga ttcatatagg atttgacttt
    48841 ctcaatatct aatagatagt tgtttattta cttaattata tttctctata tgtattatcg
    48901 attaaattag atttagcttt atacattatt ttttatattt ttcaaattgt atactcataa
    48961 atccagaagt attctaatgt gtttataata ctttttttca tattttaaat taaataacaa
    49021 atcattatat ttacaagtat catttatcaa taaacaatat taaatgaaga atatgtctga
    49081 agattcaaag tgatactgat aatattaatt actaaaaaag cagtaaatct tttacagatt
    49141 tactgcttat agttataaat aataaaacta tctataataa atgtactata ctcaatactt
    49201 cattcaatat agtaataaca aatctacttt attcctatat aaatatgaac ttcttgtttc
    49261 tttgtatcaa aagtattaca ttgatactct tcaaaatcac ttatataagt cctatcaaaa
    49321 tccatttgcc aaaactcaaa ccaaaaatct cctacttctt tttgacctcc tactataaca
    49381 aactttgcat acttacctgc tggtataact ttactaataa tactttctcc aacagtatta
    49441 ttagtgttta attcttctaa attcttctct ttatcagaat tactatttac ttcacaacat
    49501 gcaacaaagc tatacggact tgtaaaatca ccctggtaat ctgtatatag acctattgtc
    49561 ttgtcattct ttttaccctt tatagcatta tatatccctt tgcccataaa ttttttccac
    49621 aattcaccta tatcatttac cgcttgtcca tctttatttg tagtctcctt cgatattcct
    49681 ataactattt tctcatttat ctctactatt tcataattca tactttatac ctcactttgt
    49741 ttttattaat atattttatt ttgaactaat tcaattataa tttataatat acgacacctt
    49801 tatgtcatat ttttaatata attaaactca gtgagatatt atatactaaa tgcaagatat
    49861 tatatattta ataaaatctt taatctagca ttatattata atgaataaat tttagacaac
    49921 tcccttagtc tagttattac attatcccta acatctttag gttcaagtac ttcaacattg
    49981 tcaccaaatg ataaaatata tccataaatc cattcaccaa taggaaattc tgtaattaca
    50041 tcatatgtat catcttcatt tttagttatt aaatccttat taaaatcatc aaatactcta
    50101 aaaagcatct tttctttaaa cctcaatttc aacgttatag tattttcctt aattacttta
    50161 gaatcattca aacatacttc ttctattatc tttcttgaaa atacttcatc ctttatagat
    50221 aaattcctta tcctactaat tctaaatatc ctaaaatcat cttttagttt acaaaatcca
    50281 tacaagtacc aagtcttact cttatacata agcttcagtg gttcgacagt tctgtttgtc
    50341 tggcttgaca aactatttac ataattaaaa tttatagtat tacgccttaa aatagcttct
    50401 tttatttttg taaatttatc atcttcatta aaattacttc cccattcagt aaagtctatt
    50461 tcaatccagt ttgaaaaatt ctgctctcca aatattgagc caattttatt tactactgaa
    50521 tttatttctg gatacttagt cgcctgtaat gttttcagtg ccactattaa actctcttta
    50581 tctttttttg acaatatagc cttgtctata gaatattctt ctattaaaga tatccctcct
    50641 cctttgcctt tcgtcatata tactggtact cccgacatag acagagtttc tatatctcta
    50701 tatatggttc ttgtagaaac ttcaaatcta tctgccaact ctttagctgt tactaatttt
    50761 ttatttaata gaattactat tatttctgtt aatctattta ttttcattca ttaccaccta
    50821 ctaaaattat taaatttatt taatctaaat taatcatact aatttttaaa taaataaaat
    50881 cttagaatct tatctaaatt attcttacat gattttattt actttctatt atctttctca
    50941 ctttggatat tatcatctta atttatttat tactatatca atttacttat tatcatctca
    51001 tttgttatcg tcttacttaa tttacttatt tctatatcaa ttcacttatt attacctcac
    51061 ttgttatcat cttacttaat ttacttattt ctatatcaat ttacttatta tcatctcatt
    51121 tgttatcgtc ttacttaatt tacttattgc tatgtcaatt catttattat tatctcactt
    51181 gttatcgtct tatttaattt acttatttct atatcaattc acttattatc atcttaattc
    51241 atttgattat tatcatttac tttattcaat ttctatatca aaaattagta tttgtactta
    51301 atacttaaaa ttaatttaaa gtctttacat attatttatt ttttattgta atattaattt
    51361 ccatactttg ctaagctact tccactcatt tattttaaaa tttcaattta ctatttctca
    51421 attctatatt attatttttc aattttatat tactaatttt aaagcttttt agctattatt
    51481 cctacaatat ttaaacaatt ttttaataat aaagctatat tacaatatat tcaaaatatg
    51541 taatatttta gatatttttc gttgacaatg ttaaattttt gttttatcct taattaagga
    51601 catgttattg acatttctga aacttatttg aaatagtttt ttcattttat ttaggaaaac
    51661 gtattatacc taagaaaacg tattttctca tttcagataa gtaaaatatt tattcttttg
    51721 gggaggaaat catggaaatt aataaaaaac attttattca agtattttta acttgcttaa
    51781 tcttggtagt aatatgtgaa tttatagggc aaagaactat agctattgga aaagcctcta
    51841 tagtactgtt ccctatgctt tatgcagtta taattggact tataataaca ccagatttat
    51901 taggtaaaaa aattaaagca cttaaaaaag tggttggaga aaaagaaata aatattgctg
    51961 gtgaagttgt tggaattgca ctagtaatgc ttggtataaa atatggtact acagttggac
    52021 caaacattga caaaataatt caagctggac cagcatttat cgctcaagaa tttggtcata
    52081 tacttgcacc aatcgttgca ttacctcttg cattaatgtt tggaatgaaa agagaagctg
    52141 ttggagctac tgcaagtata agtcgtgaac cttctttagg agttatatca gaaaaatatg
    52201 ggataaactc accagaaggt agtggtgtac ttggtacata tttaatggga acagttcttg
    52261 gtactatata ctttagtgta ctaggttcaa tatctattta tagtggtctt cacccatatg
    52321 ctttgggaat ggcctgtggt gttggtagtg gaagtatgat gacagcagct gctggttcat
    52381 tatctaccat ggtaccacct gaaatggcag atacaatact tgcctatgct gcaacaagca
    52441 atatgatgtc tagtataaca ggaattatat tcttagtttt tgtatcctta ccatttacta
    52501 attttatgta taagatttta gaacctaaat tttcgagaaa taaaaaaact aaagaaatta
    52561 aatctacaga aggagagtgc taataaatgt ttgctaattt aaatttaaag aaaagttcat
    52621 atcaattatt ggttatgtct gttattggag ttataattct tataggacaa agaattagcg
    52681 ttggtacatc tatagttaca gctcttcctg gtatggtgat gctaatatta gctgctatgg
    52741 cagctatgat tataaaagat ttatttccta aatcaatctt tccagctttt ggatttgcaa
    52801 ctataatcgg ccttttactt agtatgccat atagtccaac atctgaagta ttcttaacta
    52861 acactaataa tattaacttt atggctataa ctactccact actagctttt gcaggaattt
    52921 ctgttggaaa caaaatagaa gctttaaaag aaatgtcatg gaaaatagtt ataatttcac
    52981 ttattgtatt tacaactata ttctttgcat gtgcgagtat agctcatata gttttaagta
    53041 ttcaaggtaa aatataggag gaatttatta tgaataaaga acaattaaaa tctctagtaa
    53101 taaaaactat agatgaaaat agagaaaaaa tattaaaaat aggtcaagga atatacaaaa
    53161 atccagaata tggatataaa gaatttaaaa ctacagaagc tgtttcaaac ttttttgagc
    53221 aagaattaaa tttatctgta gaaaaaaata tagcagttac aggatgcaaa gcagatgcaa
    53281 attctagcaa gaaaggtcct catatatcta tacttggaga attggatggt atatcatgta
    53341 aagaacataa agatgctaat gaaataggtg cttctcatac ttgtggacat aatattcaaa
    53401 tagctggaat gttaggtgct gctgttggtt tagtaaaaag tggcgtttta gaacatttag
    53461 atggtaaagt atcttttatg gctactcctg ctgaagagtt tattgagttg gaatacagag
    53521 agcaattaaa aaaagaagga aaaataactt attttggtgg aaaacaagaa ttaataaaaa
    53581 gaggttattt tgatgatata gacatatcta tgatgtttca tgcttctgat ttaggagaag
    53641 ataaggctct agttggtcct gagagtaatg gatttgttgg aaaaaaggtt aaatttatag
    53701 gtaaagaatc tcatgctggt tctgctccac atgatggaat aaatgcttta aatgcagcaa
    53761 tgcttgctat aaacaacgtg aatgcactta gagaaacttt taaagagtct gaaagagtta
    53821 gattccaccc tatcatcaca aaaggtggag atatagtaaa tgttgttcct gctgatgttc
    53881 atatggaatc atatgttaga gctagaacta taaatggtat gattgatgct aatgaaagaa
    53941 taaataaggc tttgatggct ggtggaatgg cagttggagc tgatgttgag ataactgaaa
    54001 ttcctggata tcttccaata ttacgataca aaagtcttga taatttattt aaaaacaatc
    54061 ttgaagattt aggtctaaaa ggaaaagtta ttgatggtgg agattttaca ggctcttttg
    54121 attttggaga tgtgtctcat ataatgccta ctcttcaccc tatgattggt ggtgtaaaag
    54181 gagctcttca tacaagagat tttgaaatag ttgatgaaga tttagcttac ataattcctg
    54241 ctaaagcaat ggcacttaca gttgtagacc ttctttttga taatgctaag gatgctaaag
    54301 atatattaga tacctttact ccagttatga ctaaagaaga atatctaaca ttcttagaaa
    54361 aacacgataa aactttataa gtctattttt ataatagggt ggtatctact gtaaaagtta
    54421 taccactctt tgtttttgta acagtatact tcttttcttt tagtttttag attaaactaa
    54481 gatatattat cctccttaaa acttttagag ctacgttgaa atatcagtag aactatgcta
    54541 tattctttct aattaatata aatttctatt ctaattcaag gtggtgaaaa aatgtttaat
    54601 gcaggaaatc gaattataaa tacatggttg taccctattc aagatggctt tgtcttgatt
    54661 gatactggat atgaaaatgg ttttaaacat ttcaaaaaac gaatttctaa attcaacata
    54721 aaaatcaaag atattcgata catatttcta actcatgctc atgatgacca tgttggtttt
    54781 ctaaatcaga ttctagacga atctcctaat acaaagattg ttatgcatga taaagcttta
    54841 gaaattctat ataaaggtca aaactctttt attggtggtt gtaccagccg tactgccttt
    54901 ctcttttgcc aaattatgaa actatttgga aaaggtgagc atagtttttc tccacttaaa
    54961 caagaatttg aaaaaaggtg tattcttgtg tctgacaaga atcgtaaaga aattgaaaaa
    55021 gaactaaatg gaaaaattat agatacacca ggacatactg ctgattcaat ttcactacta
    55081 attgatgaag gtgttttatt ttgtggagat tctgcaatga atggatttcc aagtactcac
    55141 aaaattacca tatttgcaga aagcaaacta gaatttattc aatcttggaa aacaatcatc
    55201 aatacaaaac ctaaaatgat ttatcctgga catggaaaac catttgaata cagtaaatta
    55261 gaacaaaatc taatctatgt aaataaaata aatttatatc ctctacataa ttcaaaagat
    55321 attcacaggt ttttgtagaa aatacaaagt aaatttattt gattaattaa aaaatctaac
    55381 actttactac gctacttatt ttaataactt aatcttccac tagcttttca taaaattttg
    55441 ttttaaaatt aattttaaag cgcatatgtt atttaaatac attagataaa attcgtcatt
    55501 aatctactta aagcatattt aactaacacc actcaaccag aaaattcaga aaactgcatt
    55561 gacacaggaa aaagtttatt ttatactttt tttaggacat attgtggaca cgtcttaaat
    55621 cgacaaacag aatttaaatt gtaagattaa ccacaatact tattttttaa ttatattttt
    55681 aaacattagg gaggatatta tgaatgataa cgtagttaag aagaaaaact tttttgacag
    55741 gacattaaac agaatagaaa ctgttggtaa taaactacca gacccagtta caatattttt
    55801 agggttatgt gtacttttac ttatactatc tagtctagtt ggttctatgg gtatatcagt
    55861 agttcatcct ggtactggag aaactataac cgctgtaaat ttattgactg tagaacagct
    55921 tcaaattctt ttaggaaaca tagtcagcaa tttccaaggg tttgctcctt tgggtctagt
    55981 tctagtaact atgataggtg ctggtgtatg tgacaaaaca ggacttatga cagcaacaat
    56041 caaagcatca gtaagcaaga ttcctgaaac aagagtaact cttgttgtaa tgactatagg
    56101 tatgcttgcc aatatagctt cagatgcagg tacaatatta tttccaccat tagctgcact
    56161 tgtatatctt ggtgttggta gacatccact tataggttta ttttctggat atgcagcagt
    56221 ctgtctagga tttgccgcaa acattatgat aagtgtcaat gatatacttg ctgcaagttt
    56281 tacagttcca gcagctcaaa tgattgattc tggatttcaa gccaatgcaa caatgaactt
    56341 attttttatg atagcatcaa cttttgttct aatacttttg gcaacatggg taacagaaaa
    56401 aattgtagct cctagatttg gtaaatatga aggaaatgca gaactagatg ttgatggaag
    56461 tcttagtgat gtagaaaaga aagggcttaa aaaagctggt ataagtatat taatatatgt
    56521 ggctattata gtagctctta gtgtaatcgg taaaaaacca ttcttagctg acccagaaac
    56581 aggagattta ctatcaaaca atgctcctct tatgaaaggt atggtaccta taatagcact
    56641 agcatttttc atacctggtg ttgtatacgg aaaaactata ggtaaaataa agaaggataa
    56701 ggatgtagtc tctataatgg ctagtgcaat gagtgatatg ggtggatata taatactagc
    56761 atttgctgct tcacaatttt tgcaattatt cacaaatagt aatttaggtc tgatactagc
    56821 tgtaaagggc ggagaatttt taaaatcagc aggaataaat ggacctttat tgttgatagg
    56881 atttattata ttatcatgtt ttataaattt atttataggt agtgcatctg caaagtgggc
    56941 tattcttgca cctatatttg taccaatgtt tatgatggtt ggatacaatc cagcacttac
    57001 tcagatggct tatcgtatag gtgattgtat aacaaatcca cttagcccat tatttccgta
    57061 cttccctatt atactagcat tcacaagaaa atacgataaa gatgctggta tgggtactgt
    57121 aattgctaat atgataccat actctatatc attcttaata gtgtggacta tactattaat
    57181 attgtttatg gtatttaata ttccactagg acctggaata cttccttcat atagcatgta
    57241 atttatttaa atctttctaa aaggagaaat aatttatgtt agataaaaat agacttataa
    57301 ataattttat ggatatggtt agaattgata gcccatctaa tcaagaatta gaaatgtcta
    57361 agtggttggt aaactactta aaagaaagaa atatagacgc cattatagat gatgcaggtg
    57421 aaaaatatgg tggtaataca ggtaatgtca ttgcctatat aaaaggtgaa gaaggaagta
    57481 gaccactttg tttatgtgca cacatggacc aagttcaacc ttgtttaggt gtaaaaccaa
    57541 tactagatgg taatgtagtt agaagtgatg gaactactac acttggtgca gatgataaag
    57601 ctggaatagc tgctatactt gaagctttag aacatgttat tacagaaaaa ataccacata
    57661 gagatattta tctttgtttt acaatctgtg aggaagccgg tatgcatggt gtcaaaaact
    57721 ttaatcctga caacttgcct tgtaaagaca tggtgatttt agattctggt ggagctattg
    57781 gttcgatagc atacaaagct cctgctcaac aatctataaa aatctctttt catggaaaga
    57841 aagcacatgc tggtatagaa cctgaaaaag ggttaaatgc tatattagta gcctctcatg
    57901 caataagcaa catgcacata ggcagaatag attcattgac tacttcaaat ataggtaaaa
    57961 tagaaggtgg tggagctaca aacatagtaa ctgataaggt tacattgact gctgaaatta
    58021 ggtctcatat acctgaaact ttagagtatg agcttaatca tatggaaaaa tgttgtaagg
    58081 atgctgcatc taaatttaat actacttata cttttgaaca tagtatgtct taccctagtt
    58141 ttgaacttag tagagatagt catgttttca agttaagtga agaagcaata agacaagttg
    58201 gtgttgttcc aaatccaatg gtaattggtg gtggaagtga cgcaaatata ttagctaatc
    58261 ttggatataa ttgtgctata ttaagtctag gtatgtatga tgtacacaca gttaatgaat
    58321 atgtaaatat agacgaatta tatgatactg ccaaaatagt ttatcatatg attaaattat
    58381 aaatatcata atataactct ttaaattata aaaataaaaa cctatgtatc ttcaacttta
    58441 taagttatat attaaagttg ttttacatag gttttagtat tttatataat aatttgtttt
    58501 aacatttttc ataataagct tcaatatttt gcataataat ttgttctagc atttttaata
    58561 acaagcttta gtattttata ttaataattt attctagtat tttacataat catttgttct
    58621 aatttttttc ataataagct ttaatacttt atatagtaat ttgttgtaga attttataca
    58681 atataatgat ttatacagtt ttataaaata tcttaaaaca gtatttcagt aatatttttt
    58741 ggtcttcctc caccaatact agtctctttt gcacatattc gacctaaacc tgcatttact
    58801 attttattta atatacgtct tgcacttctt tcacttacat ttagatactc tgctaactct
    58861 tttgaatcat aaatcttact ttttctattc tcatttatag caataatttt tgcaactgac
    58921 tcacaactca ttccagtctt tttagatatt tcgattacct tttcatcaga tagcatcaaa
    58981 gaataattta attcattttc ggaagctaaa ggtcctctta tgttttcatc ttcatctacc
    59041 aaatatatac caatttcttt tgaatctatg gagtgtctta atgctttatg tgcattattt
    59101 tcagcctgat acgcagttac tccagtacca attcctatac taagagaaaa gcccatgtct
    59161 tttatctctc tctttagatt gaatagctta tcataattat actcattatc agctacccct
    59221 ttatgaacaa atacaacata atcatttctt ccaagtaaaa ataaggaacc ttgaatactt
    59281 cttacatagt ttactacaag cttatccata tctgattttt ttatcatgtc agaataatag
    59341 ttatctatct tctctttata atctattaaa ctcaatattt caacagcaat ttgagaaaat
    59401 cttgccttac ttagagcata ttcactcttt accttgtcat aactttcttt gattaattgt
    59461 atagtagctt gtaaacgaaa tacaggatag cctctttctt ttaattcatt atatactgca
    59521 ccaaaaccag ttaacattat atccgtctta ttttcttcaa ataattttat atgccattct
    59581 acaagttcag actctcctac ttccaaagaa aatggattac aaaatacact cgttgcttta
    59641 atatcaaatt ctttaagtgc atcttccaca acatatctat caactacatc tatactgaat
    59701 ttatctaatt ttatatttgc actttttatt gcccaaaatg ccttcattat actcgtccca
    59761 cttctcggta caaatgaatg tggcttactt atctcatact tagattttat aaattcataa
    59821 actgcacatc ctgtaaatat aatagcatca cattcgtctt cacatttaga aataacttct
    59881 attgtatcta ctactttttc tcttacatat attttagtct ttaaatcact gtctatctgt
    59941 tttaaatcat cctttatctt aaacccagag tctgaaggac ctataatacc cactatcata
    60001 aacttcgctc ctaatccata aatattatac tttttaaaaa ttatatcctc actattttct
    60061 acttctattt aattattttg aactactcca tcctacctac atttagaatg gaataattag
    60121 cttatttttg ataaagtaac ttctcaaaat cagaacttgg aataggctta caataataat
    60181 aaccttgaat taccacacaa tctaaactca ctaaaaattc agcttgttct tttgtctcta
    60241 caccttctgc cactacatcc atatctaaat cttttgccat ggctatagtg tgctttaaaa
    60301 ctattttttc tctgtctgtg attccttcct cattaaagaa accacaatct atctttaatg
    60361 tatcaatatt aatatttttt aacatattta atgaagaata tgctgaacca aagtcatcca
    60421 tatttaaaac aataccatcc attctaaggt cggctattat cttagtaaat aattttatat
    60481 ttttaataaa taaactttct gtaagctcta attctaaaaa agattttggt atactatatt
    60541 tatttattaa acttaaaaca atttctttaa aatgtggatt atgcaaatgt aatcttgata
    60601 catttacaga gataggaact ggctcttcac ctaaatctat ccattttcta atcaaagaac
    60661 atacttgttc ccatacatac atatctaatc tgataataaa cccattcttc tcaaatagtg
    60721 aaataaattt aattggaggt attatacctt tttctggatg aacccatcta accaatgctt
    60781 ctgcaccaac aattttattt gcattaagat tatacttagg ttgtaaatat acatggaatt
    60841 gcccattttc aagtgcgtat tccatttccc tttccatctg tttttcttca agtgcatcat
    60901 ttcttatagt atcatcataa aatatatagt tgttgatact ttgtttcttt acttttttgt
    60961 gagcatatcc tgccatttca cacgcatttg taattggaat atgattatcc aaaattctat
    61021 aaaccccaaa acatggtact aacatatatt caaatttttt tctatttaag ctatttttaa
    61081 tcttataaat tactttatga atatctctat cagagtaact ctcataaaaa atgcaaaata
    61141 catctgcata catacgacaa catataccat tagaaccaat gtttttttga atcaactctg
    61201 caacatatat taaagcttta tctcctcctc taactccata aatgtcatta attaccttga
    61261 acttatctat atccatcatt ataattgcat aacgcttgtc aggatatctt ttaagcatta
    61321 aacttatttg ttcacaaaaa ctttcataat tgtatagtcc tgttaatgta tctttttggt
    61381 ttttatgtag ttgcataaga taatctatat tttttatagc aactaaaata tgtgtttgtt
    61441 tctcacctaa cttattttta ctactaatct ttaacatata aattaatgcc caatagtact
    61501 ttttatctat tcctaaacgt ctatactcaa aatttagttc taaatcgtct tgcttgctat
    61561 tattaagact atcaagagat tttagaaggt ggttatcatt aaataatatt atatcatcag
    61621 gatgaattaa atattttttt atgtatgaaa aagttttttc aagattttcc tttataggaa
    61681 aactaaaaat attgctctct gattgataaa ttggagtaat taaattcgta tcaatgcaaa
    61741 tagataaaat tatatcatat gtattataag ctaatttttc ataagcttta gaataccctt
    61801 ttatcattaa atcatcaaaa taaaccttat caactaactc tttatgttta aataaaatat
    61861 tattcgtcga atcagctaag tcactaatta ctttcatttc attatttcta agtttgttct
    61921 tattataata cctcttctta tcttggtaca ttctctcatc agcaacttta attagcttat
    61981 gtatatcaat attatcgtca ctccaaatac tgcccactgc tacactatat atcatctcat
    62041 ccttaaattc ttcacttaac caactcacta attcttcaaa tagttgtttt gatatatctt
    62101 cacataatac aacaaactca tctcctccaa tacggtaaac attataagaa tgaaagtatt
    62161 tttttattat tacacatgct gacacaatag cagaatcgcc attagcatgt ccaaagttat
    62221 cattaatatc ttttaaccca tttatatcta caaatacaac tcctatggat ttaacttttc
    62281 ctttttgaaa attatctata tacttaatat atttatttct attatatgca ccagtcaaga
    62341 agtcatagta gctcatataa tttaatttat tttctacttt tctttttttc atctcagtta
    62401 ataaaaaata agatagggat gtcaaaagag aggtatctcc aacagcttta tgtggattat
    62461 caactccaat aaaccctact actttatcat cttgttttag tgaagatgtc attaaacttt
    62521 caattttttg aggttttaaa atttcatatt ctattggctg ttcttctttt atattttcta
    62581 tatcatcaat tattacaaaa cctttttgtt cgaataataa aaaccaattc tttaattcat
    62641 taatatcaag atttgttagt gcctgttttt gttcatcaac accttcattg caccattcat
    62701 atgtattagt tacttttgtt ctatcttctg atacttcaaa aacatatgct ctatcagctt
    62761 tatgaaattt accaatattg gttaatacaa gatttacagc atcagaaaaa ttagattctg
    62821 ttataagatg tttaatacat ccaactaata actcctttat ctctaatttt tctgctattg
    62881 acttacttat atcttccttt tctgtaatat caagagctat ttctaatcgt gcatgtttgc
    62941 cctcccattt aattaacttg tcctttaata taaaatgtct atttgttcga gtattcgtat
    63001 tttcccatat gtaatattca tcttctttta aaatagagtt tgtacaaaat tcgcagggag
    63061 aatctttccc ctgtaatgct ttataacatt ttaaatggga tatatcatta agtcccattg
    63121 cctttttccc aatttcatta atatataaaa gttcatatgt atctaaagaa gaaacatata
    63181 caatttcatc caactcatct attaaattta ttacatccat ttatatatat ctccttttat
    63241 tcattttcca gattgaattt ttaaagcttt taaaattttg ctatatattt ggcaatgata
    63301 ttatacttct ttatgtttta aaatagtacc ttaatgaggt tctatttttt agtaaataga
    63361 attattattg tgtcaatcgt acaatagagt tttgtaatac ttaatttaat atatttataa
    63421 ttaactatct tattatgtat ttacaattaa ttctcatata aatgacaaat ctccacctca
    63481 attaagtatt ccaatcatat atgaggataa tacttcattc atttaaaaat ataaaactat
    63541 tatatattaa aatttcttca ataataaatt atttagattg ttactttgat atattatata
    63601 atatcacaaa ggctgatata aaaagacaaa aagggcaatt tttttatatc aaaaaaaatg
    63661 ttaaattgat attatccata tataaattga tattatccat ataggtgcta tatttaacaa
    63721 ttctacttac ttcccttaca cttattagca tatagttatt aagagtttgt tgcaaaacaa
    63781 cacttagcac actttaaaaa gtgtggtcta ataagtaatc aacgaagaag acataataaa
    63841 gcataaaata ggatatactt ttccacgtca tcaaaattga ggattttatt attaatatat
    63901 gataaaatat gcttaataaa ttaaatttta atgggagaat agttatgaaa atatttagtt
    63961 tcttgttgtt tgtagtggga atatgttttt gtattgctgg atttatgggg cattcctcag
    64021 ctttttctgg tgcaacattg agtttttttg caactacaat gatagctgta agacaagtca
    64081 aaactaagaa aaaatgaaat aggcaaatcc taactttata agttaatatt acataagtaa
    64141 ttagtctaaa attagatact ttttctatta caaaaataca tcatccactt tgtattctct
    64201 taaaaaaaat aaaatagcta tgtaaattca agattagata gactaactct ctatccattt
    64261 cattgtaaaa tatacatagc tatttgtatt cgatttaaaa tacttagatt ttcttacata
    64321 acaaataatt tctatctgat tattactcat gttcatttat taaccactca gcaactaatc
    64381 atttagtatc tattcatccg ccatacggta acctacccca acctcagtca aaatatattc
    64441 tggctgagca ggattctttt caattttcct tcttatactt gccataaaaa ctctaagcga
    64501 ctgattttca ctttcatagt aatttcccca aactttatct attataaact tatgggttaa
    64561 gactcttcct gaatacttag acatcaactc aataatctta tattcgattg gagttaaatg
    64621 tatttcttca ccattaattg acacaatatg attttcataa tctatcttta ggtttttaac
    64681 ttcaaaagac tttggagcat cattatttat attatcctgt tgagctttat ttctaagagc
    64741 cacacgtact ctagccaaaa gctctgttac actaaaaggt ttagttaaat aatcgtctgc
    64801 tcctccatct aaagcttcca ccttatctct ctcatgctct ctcgctgaaa caacaattat
    64861 tttattagtc tttgcacatg ccctaactcg tcctattacc tcaatcccat caatatctgg
    64921 tagtcctaaa tccaaaatta tcaaatctgg gtcaagagaa tgtataagtg atatagctgt
    64981 tcctccatta tctgtctcta cacacctata attttgagtt tcaagagata cttttataaa
    65041 tttacaaatt ggcttatcat cttctacaat tagaactaat ggctttattt ccacttgtct
    65101 ttcccctcct catcatacat aggtatgcta aatctaaatg tagctcctcc agaaggatta
    65161 ttaaaggcga caatttctcc accatgagct tctactatag atttacatat ctccaatcca
    65221 agaccaatac ctcttctttc aagatttcta gacttattct tagtataaaa cctattaaaa
    65281 atattcccga tatcttcatt tggtattcct tttccattat ctgcaacttc aaatagtact
    65341 tgatttgact ctttttttac agttagttct atcttagaat ttttaggtgt atgccttata
    65401 gcattatcaa ttagatttac taacacttgt tctattaata atacatccac atgaacgatt
    65461 attatctcat ctggaatatt tgtttttatg tctctactat tggcaaactt tttgactctt
    65521 aatatagatt cagctattat ttcatcaaca acctctggtc gtttttcaat atccaatttt
    65581 ccttcatcta ttctggtcat actaagtata ttctcaacag aatgagttag ccaactcgta
    65641 tcttcatata tatttttcaa taattctact ctagtttctt tatctatcac atcatcattt
    65701 tcaagtattg ttgaagatga acccaatata cttgtaagtg gagttcttaa atcatgagaa
    65761 attgacctaa gcaagtttcc tcttaacctc tctctctctg cctcaaggtt tgctttttta
    65821 tttttctcaa ataaattttc tctatcaatt gccaacgcaa cctgtgttga aactgcttct
    65881 aatagtatct tttcattttc tgtaataata tctatcttaa aacacgcaac acctataaca
    65941 ccaagaacat ttgattcttg accttttata gggaaataat atgcactgct gtttttacaa
    66001 tattttgtcc caattccaac tgggttacct gtcctaaaag cttcttttat agcttccttt
    66061 tctaatactg aatggaatat attctcactt ccatcattgt tacaaatata aatacttggc
    66121 ttacctagat tattattctc atctgcaata gtcactatta cagttctatt taatatattt
    66181 actaaattag acccacaaaa ttcaataatt tgatttttat tttttgcttt aagcaacgtt
    66241 ttgttattct catagagcaa tcttatcatt ttttctctct tatgagaaag tctcacttct
    66301 ctttttatcc tagaagttaa agtacttgtt ataattgctg ccattagcat aatacaaaag
    66361 gtcataggat aatcttttct ataagctaaa aaagtatata atggatgcgt aaagaaaaaa
    66421 ttaaatgata gcactcctat tactgaagaa agtattccaa aaaaatatcc ataggttata
    66481 cttgtagcaa atagtacacc taatatgtat actagtataa tattagattc attaaaacct
    66541 accttttcaa aaactactga tattccagta gcaattgtca taaccaatat agtttttatg
    66601 aagtccttaa taattatctt tttactgaga tagccatctt catcataatc atactctttt
    66661 aagtcttcat gttgtagtcg ttcctttttc atttactaca attcctcctt attgttactg
    66721 tttaaattgg ctctatttta tataatacaa ttttatcata ataaattcaa tcaatacatt
    66781 taattaatgt acttaaatta ctaaaaggtg ctgtcttaaa atgaaaataa atctctattt
    66841 caaaacagca cctatatatt taaattacta atttagtttt tacatactta aatcaatagt
    66901 tttattcaat ttcataaatt ataatacttc aattataaaa catttctatc caacaagcat
    66961 aaatataaag tgggcacata tacctgcaca taaaccacct atagtatgcg aaagtatcgc
    67021 tttaccagcc aatggtcttg catctaaagc atccatcata cctatgtgtg tacttaaata
    67081 tccactccaa cacataccca ttgctgtgaa tactgctata tcattaggag ttatagcgcc
    67141 tgattttata aactctggta ctaaagatat tgctgctcca acagctccta atgcagttac
    67201 agggaatgct attgcctctg gtgatgtgaa tccaaataat ggttctatta tgaagctaat
    67261 cttatcacca atagcaggta ataattttat accttcatat gcagctcctg tgtaaacagc
    67321 ttgacctgta gcagggtctg tagatggtcc aaaagttaat aacataacta atgtacaaac
    67381 tactaaaact cctggtatta tagccatacc catttcaaca cctaacttac caccttcaag
    67441 tatagcatcc aatgttcttt ggaatacatt accatccctt atttctctaa actcttcaag
    67501 ttttgcacct ttatcattta tttgcttttc agtatcattt ttagggtcat aattataata
    67561 ctttttagta aaagtcaaca taattctaac actaataata ctacctatta ttgccccaac
    67621 attacctatt atagctggta gtacatattc tttaccttga gctatcataa aagttgttac
    67681 aataagtccc ataccaaagg ctgttcctaa attacataaa gcaggtactt gatacttctt
    67741 aaaatattgt gtaaatgttt tgtctttagc aaatggtata atagctggat tatcagataa
    67801 atatgttgca actactcctg ctatactagc accaggtaag ccccatatag gtctcataag
    67861 acccttaaat atcttattaa ctaaagatat tactccaaac tctgaaagca atgcactaag
    67921 tgcacctgca agaactgcca tagccattat taaaaatact gtgtctaata aaagcgcatg
    67981 tgctgtactc attattactt taaacatcat tcctgcaccc atgatgcttc ctacatatcc
    68041 aaatcctacc gccaatagta caataaatac gaaggtttcc atacttactg ccttgactct
    68101 tctcttatcc gacagctttt ccatcttgaa atcttccccc ttttaatttt aaattaaggt
    68161 tcctaacatt ggtacaaatt ttttggtaca aactgagttc taaaacttac actcgtaatg
    68221 caagttgtca gttttttgaa ataaaaaaaa attacgttta tagaataaga atatcctctt
    68281 taatttggat actcttattc tattttatgt tattatatta tcatcctttt gtttaaaagt
    68341 caattttttc tatttttgtt gtttaatttt atttatactc tttttatatt tttcattttc
    68401 ttttatcttt gtaagtactc catataagtt gacttttcta aatacagtag ttataaatac
    68461 caatcctaat gcaattgaac ttgcacacga taatgtactc accccatatt ctacagcttt
    68521 tatataatta ttggtcaaaa cagaatacat agtattatat attccataac ctggcactaa
    68581 tattattaaa cagcaaacac ttaatgtagt tgctggagtc atataaattc ttgcacataa
    68641 ctcacaatat atcgcaaaac aaactgtagc tataaaaaaa cataagtttt ctgttactcc
    68701 catatttaaa agaaatttat acgaaaacca agctatactt ccaccgattc ctgctagtat
    68761 taagtttttt cctttcatat taaatagcac tccaaagctt aaggcagtaa aaaaagctgc
    68821 tattacttct ataaacaaat gcacttatat cccccctaac ttgaagtaca atccaagtac
    68881 caagaacatt cctactgcta tagatacacc tacaaaaaat acttctgcta attttgcaag
    68941 accagaaatc aactgtccat ctaacaaatc tcttaatgca ttagtcaaag caagcccggg
    69001 aactaagagc attattgctc ctgctattaa atggtctaac gtctttatga atccgagctt
    69061 taaaattaaa attgaacaag aagctataat aactgctcca attgcattta caaaaaagtc
    69121 attaagggaa gatttactta aatacataat aacaaactta gtcagaatcc caacagtaaa
    69181 tgcagctata aattcttcca catttcctcc aaataatatc gaaaaagttg ctgctgcaat
    69241 acctgcaaaa aatattgtta ttaaatccga gtaatagtta tcttcactta tttcatctaa
    69301 aattttctca cataattcaa tatctaaatt atttatactt attgctcttg ataatgagtt
    69361 aacttcatga accaagttta ggtctactct tcttgagctt attcttttaa ttgctgaatg
    69421 taatttccca tctacaaata cagatgccat tacagctgtt ggagttgcaa atacatctac
    69481 gtggtctatt ccaaaagatt gacatattct agctatcgtt tcttcaactc tataggtttc
    69541 tcctccactt tgcaacatag ctttacctgc atttgaggaa aagtttaaaa ttctatctat
    69601 atccacaaaa catatctccc attcttttat agtattattc atattttaat acaagatatt
    69661 atttatttaa actattttaa ataattcata tccaacattt acattttatg aaaaaacttg
    69721 ttttttatgc ttgtcaaaat caaattttaa gcttgtttac accataaaat ggctgaatta
    69781 atatttgaca aacactttca accatttata taaccttcta aattgtataa ctttttacta
    69841 caaataaaat tatatctctt ttaattcttt ctcttgagta tttagcttat agtaacttca
    69901 tatttatata tgtacaatat aaaacattat ttttatgata caaaatataa tttgtaaatg
    69961 tatatatgta ttaactgtgt atatataaat tattcttaac cttatcagtt ttttcatata
    70021 tcttcatcta taccgaccat atattaatta cattgaccat atattaataa atgatattac
    70081 atagacttaa gtatattaaa aaacttaaat ttagttattt aacaacataa tactctaatt
    70141 taatctataa aaatccatac ctaatataat gcaactctta ttttaacacc atctattaca
    70201 caaaacaaca tattaaaaag taaaatacaa aatatctact ataaacctta ttttaatact
    70261 gaatatatat tataatatat ttaatgtagc ttaaatatag tttaaacata aagaaaggaa
    70321 acggtatatg ctaagaaaag ataaagttct attatctcta cataaattat gtgaaaatat
    70381 gactttaaaa gaccttcaat cagataaaac aggattcact acaatagaaa ttgctaacca
    70441 ttcatctctt gatagaagta ataccagtaa agaattaaat aacctataca atgaaaaaaa
    70501 agttctgaaa atatctggta agccaatttt atttctacat gctagtatta tagaaaattt
    70561 aattggccgt actttgaaca gtgatgaatt ttctataaat aattgtaatg agctacttaa
    70621 atcaagtaaa aatgactcag aagatatttt ttcaacatta cttggacatg attctagtct
    70681 taaactacct atagaaaaag ctaaatctgc tatactctat cctccaaaag gtcttaatac
    70741 attactaata ggacctactg gtgttggaaa aagtacattt gctgaaacaa tgtacaaata
    70801 tgctgtagaa agtaaaatct tttcttctga aagcaaattc gtagtattta actgtgctga
    70861 atatgcagaa aatgctaact tattattaag taatttattt ggttatgtca aaggttcttt
    70921 tactggtgct aataaggata aattcggcat agttgcacag gctgatggag gcatattatt
    70981 cttagatgaa atacacagat taccaccaga aggtcaagag atgctttttc ttttgatgga
    71041 caaaggcata tacagacgat taggagaatc tgacattgtg cataaagcta atgtctttat
    71101 tgtgtgtgcc acaacagaag atatacattc ttctctgctt ggaacttttt taagaagaat
    71161 ccctgttaca atcaacctac ctgctttaca ggataggtct ttaaaagaaa gattatctct
    71221 tattaaatac ttctttatta tagaatcaaa atacaccaat gcaactataa aagttcacaa
    71281 agatgtaatt aaatcattac tcctttatga ttgttttggt aatataggtc agcttaaatc
    71341 tgacatacaa cttatgagtg caagagcctt cttaaattac aaaactggac ttaaggataa
    71401 tatagaaata gatttatccc ttgttcctga ttacatctat attggtcttt taaaattgaa
    71461 tgaaaatcgt agtaatctaa ataaattatc agaacttgat tatatgcttt tttatgaatt
    71521 taatggtaat aacttagaag ttgaatatac aaaagaacta tctaaataca atatagatac
    71581 atcaaacaat ggatttaaat actctacaga gattccttat ctggaaaatg atataaggag
    71641 tatgtttata aattacatgg aaaagtactc tacaaaatta ctttcgatat cttcagtaac
    71701 tcattctgat tatacaagta atgagatttt taaagtaatc aatccaaaga tttactatgc
    71761 tgttgaacat tctttaaaag aggctgaaaa aatatcgaga aacaaataca caaaacaaac
    71821 ttatattgct ctttcaatgc atataagtgc acttatagaa aatataaatc aagacacata
    71881 taatcctaag tacaatttat ataatgataa aattttctta gataaagatt taaatatagc
    71941 taaaatagtt ttaagtataa ttgaaaatga cttacaaaca tctttaccta aagatgaagt
    72001 aaaatttata tccatgtttc taaatagcat gtatcttgaa ccaaacaatc aatctgaaag
    72061 tataggagtc ataatacttg ctcatggaaa ttcaacagca agcagtatgt gtgatgtagc
    72121 aaattcattg cttggtacaa accattgtaa tgcaattgac atgcctcttg atgtaaaagt
    72181 aagtaccata cttgataaaa ctatagagtt ggtaaaagaa tgtgacgaag gtaagggtgt
    72241 acttctttta acagatatgg gctctcttat agcttttgga gaacttattt cagaaaaaac
    72301 aaaaatcaaa actcgctcaa ttgaaatggt atctactcca atagttttag aagcagtaag
    72361 aaaaagtaca ctaccagaaa tgactttgga tgaattagct aattccttaa gctctttaaa
    72421 tccatatatt ggacgagcag caatcgattc aacagaaata aactatcctg aaaagtcaag
    72481 agagtatgta ataataacta cttgtataac aggatatggt tcagctatga aagtagcaga
    72541 ctttataaat tcttcactta aaaatattag taaatacaat attaatttag ttcctcataa
    72601 tatagaaagt tttaaaatgt ataagaataa atttagtaat actaaaattc tggcagttgt
    72661 tggaagtgta gattttaatg tagctaacac cccttttata cacatagagg aactactaaa
    72721 tggatatggc ctagatatgc taaacaaaat aatagaaggt acattcaatg ccaatagtat
    72781 tacaaatata aaagaaacaa atctatcata caacagttta ataataaact ttatgaccca
    72841 aaacttagag cttttggact ctgttaaatt attcaactat gtcaattctt ccttatttac
    72901 aataatagaa ttaatagatg aaaacttaaa gagcaaattt aagctaggat atatactaca
    72961 ttgctctttt atgatagaaa gatgttttaa aaatacaact tttccatata ataacattac
    73021 tgaattaatt agtaaaaatc atgaactata tagtttaata cgtgaagcct ttaagccaac
    73081 agaagcttat tttaatattt tgataccaga cgaagaaatt gcttatataa tagacatgat
    73141 taatgagtat ctaaataaat aaaatttata gcacttattt tgtgcatatt aattaatata
    73201 tgaaatggag gacgagattt tgaaaggaaa aataaaacag ttaacaatac ttgcattaat
    73261 ttttatattt ataactcctg tatttgcatt tgcagatact ccaccagtac caaattcttc
    73321 aagagcagca ctacttatag accaggaaac taaaagaata ttatttgaaa aaaacattga
    73381 tgaaaaaatg ccattagcga gtttaagtaa aatgatgacc tttttattgg caatagaagc
    73441 agttgataaa aatcaagtta aagagactga tatggtgaaa atagacaagt ctacagcttc
    73501 agtaggaggt tctacttgta aacttaaaga tggtgatgaa atatctctag gtgagcttat
    73561 gcagggtcta atgctagtat ctggaaatga tgctgctata gccatagcta aacatattgg
    73621 taaaactgaa aagaattttg taaatatgat gaacaagaaa gcagaagaaa taggaatgat
    73681 tgatacgtat tattttaatc caaatgggct tcctatatat actgacccag aacataaaga
    73741 acctcctatt gaaaatatgt caactgctca cgatatagtt acacttggaa agtatatgta
    73801 cgaccattat gaaaatcaag ttacaagaat aaccactatg caagtatata atgatactaa
    73861 aaaggatttt acacattata acacaaatcc tctgcttgtt tcagtacctg gtgttgatgg
    73921 aataaagaca ggatatacag ataatgctgg atattgcctt gcattttcta tgatggtacc
    73981 taaagatgct aaaaacgaaa gaaatcatag attgataggt gttgtacttg gtgatggtaa
    74041 caagaaaaat agaatttctt cttccgctac tttattgaaa tatggtaaag ataatttcca
    74101 ttctaaaaag atagcacata agggtgatat tatagagact ccttgtgttg atggtattga
    74161 tgattttaag ataacagtta aggttgataa agatttgtat ggtgttgttt cagataacga
    74221 aaatatcaat cctaaggtag tgtttaaaaa tatgaattat cctatccata agggagatat
    74281 tgttggtgtt gtaaagtatt ataatgactc tggtaaattt gttggaagtg ttgatgtaaa
    74341 aagtgaaagt aatataggat gtattccttt gaaggataag attaagatta aggttgctaa
    74401 gataaataaa aaacttgaga ttaaaaattc tgtttgtttt aaagcatagt aaagcatatt
    74461 attaaaaggg tatgttaaat ttataaagac tccactttgt ggagtctttt tgttttttac
    74521 aaaaaattaa aatagtggca acaattgagg atgtgaggga gagttgccac tattttgtat
    74581 agggtattat attatgtttt taagctagtt ttactatctt ctatgtttat ataataactc
    74641 ttgtgtgtga atttaattga taattaatat gaaaattatg tgaagtttta agttagttga
    74701 cttagactat tgtaaatttt ttcagaaaaa ttctgttcat aagtctatta gaccaccgaa
    74761 ttatttacct ataatattcc gatcaaaaaa tctattcttt tttaaaagta aggtcatgat
    74821 tattgtacat atataaaaat tccgaaaatt aatctacaca ctagtaacat taagtataat
    74881 aaatttattt tagtaaaact attaaaataa cctcataaga aactatagat taaatcaatc
    74941 aatctaatct acagtttctt gattattcct taatatttat aatttacatt atttgtttat
    75001 tttaaaacta tctgttacaa atctagtcaa tgttgaaaat aaattcgctc tgaatatagt
    75061 agatgatg
//
LOCUS       DAEPHU010000008        71877 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 01A10CD0081
            SAMN05941466-rid12468953.denovo.008, whole genome shotgun sequence.
ACCESSION   DAEPHU010000008 DAEPHU010000000
VERSION     DAEPHU010000008.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941466
            Sequence Read Archive: SRR6291087
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 71877)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 71877)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068158.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 22:43:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,892
            CDSs (total)                      :: 3,805
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 87
            rRNAs                             :: 8, 1, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 55
            CDSs (without protein)            :: 55
            Pseudo Genes (ambiguous residues) :: 0 of 55
            Pseudo Genes (frameshifted)       :: 21 of 55
            Pseudo Genes (incomplete)         :: 28 of 55
            Pseudo Genes (internal stop)      :: 16 of 55
            Pseudo Genes (multiple problems)  :: 8 of 55
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..71877
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941466-rid12468953.denovo.008"
                     /strain="01A10CD0081"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            68..141
                     /locus_tag="KR231_000564"
     tRNA            68..141
                     /locus_tag="KR231_000564"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:100..102,aa:Gly,seq:tcc)
     gene            150..266
                     /gene="rrf"
                     /locus_tag="KR231_000565"
     rRNA            150..266
                     /gene="rrf"
                     /locus_tag="KR231_000565"
                     /product="5S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00001"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00001"
     gene            540..2558
                     /locus_tag="KR231_000566"
     CDS             540..2558
                     /locus_tag="KR231_000566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HBH0002980.1"
                     /translation="MRRNTKLLTTGILSMAIVAPTMAFATESNAMENNADLNINLEKK
                     SIVLGSTSKVSVKFKEKPDADSITLKYKCYDMPLDTTLNYNQSTESYEGTINYNKDPE
                     YLNVWELQGITINSKNNPKTLNKQELEKMGLNLKDYNVTQECIIEDITSRKDVNKYLR
                     KTSAPITELTGSDRYETAVKISKEGWKNGSDKVVIINGDVSIDGIISTPLATTYNAPI
                     LLVEKNNVPNSVKSELKRLNPRDVIIIGDENAISKTTANQIKSTVNASQTRLKGSNRY
                     ETSLLIAKEIDKNHDVEKVYITNANGGEVDALTIAAKAGQDKQPIILTDKNSITDNTY
                     KWLKSEDLQNAYFIGGPQMISTNVINKVNDITKDNVTNNRVYGADRHETNANVIKKFY
                     TDDELEAVLVAKSDVLVDALAAGPLAANLKSPILITPKTYVSAYHKENLEAKSANKVY
                     KIGGGLTSKVMNSIASSLSKHNTTPTEPGNSGGKTVMIDPGHGGSDTGTTGKPLGGIK
                     EKDYTLNTSLATTEYLRSKGFNVIMTRDTDKTLSLGNRTALSNSLRPDLFTSIHYNAS
                     DTTGNGVEVFYKLKDKDGGTTKTVATNILNRILEKFNLKNRGAKTRTLSTDPTKDYLY
                     VLRNNDMPAVLVECAFLDNEKDMSLLNTSNKVKEMGTQIGKGIEDSLK"
     gene            3066..5078
                     /locus_tag="KR231_000567"
     CDS             3066..5078
                     /locus_tag="KR231_000567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HBH0002981.1"
                     /translation="MRRNTKLLTTGILSMAIVAPTMAFATESNAMENNADLNINLEKK
                     SIVLGSKSKVSVKFKEKPDADSITLKYKCYDMPLDTTLNYNQSTGAYEGTINYNQDPE
                     YLNVWELQGITINSKNNPKTLNRQDLEKLGLNLKDYNVTQECIIEDITSRKDVNKYLR
                     KTSSPITELTGSDRYETAVKISKEGWKNGSDKVVIINGDVSIDGIISTPLATTYNAPI
                     LLVEKNNVPNSVKSELKRLNPKDIIIIGDENAISKTTANQIKSTVNASQTRLNGSNRY
                     ETSLLIAKEIDKNHDVEKIYITNANGGEVDALTIAAKAGQDKQPIILTDKDSITDNTY
                     KWLKSEDLQNAYFIGGPQMISTNVINKVNGITKDSVTNNRVYGADRHETNANVIKKFY
                     TDDELEAVLVAKSDVLVDALAAGPLAANLKSPILITPKTYVSAYHKDNLEAKSANKVY
                     KIGGGLTSKVMSSIASSLSKHNTTPTEPGNSGGKTVMIDPGHGGSAPGNSSGGMIEKD
                     YNLNTSLATTEYLRSKGFNVIMTRDTDKTLSLGNRTALSNSLKPDLFTSIHYNGSTNK
                     QGHGVEVFYKLKDKNGGTTKTVATNILNRILEKFKLTNRGIKTRVLPSDSTKDYLYVL
                     RSNDMPAVLVECAFLDNENDMSLINSSAKVKEMGTQIGKGIEDSLK"
     gene            5320..7233
                     /locus_tag="KR231_000568"
     CDS             5320..7233
                     /locus_tag="KR231_000568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0002982.1"
                     /translation="MEYLFEKSSLKEYGNEALDKYRELLDKTGNNSRCILLLVPNNNT
                     KIRYERALRLNYSEELKVTTYISFVKKELVKYWPLIIEKCDGISTKVVSPTFISNSLS
                     EYLIVQKVKEKRIQEGYFEDITGTNKSIANSIMTNINKSAFNLIDFDFIGEKIYSSKK
                     NKDSIYRFSYTQMDEIISYYINSLLSNSILDNALSIYLYNQYLLNDDFYLKNLFTEVR
                     YIIVDSLESSSNAEVDFITEALDNTLQSYIYFDYSRDYSVFNNVDIDYINEKIISKIK
                     PKEENIKKKEIRIEDLYLLPANIELNQSSQLYNEMLDLISEKVISLIEEDVSPRDIAI
                     ISPINNSILEHQIRDSLIEKNIDVFSTKKDKKAVDYPYGNALVVATCIFYGYLDFIKD
                     DEYLSFLETLLEINRIKAFKIFNETRHLSIDNIDEHSQYRDILQYIEEKKKSDIKIHE
                     FLTQFYIDKMLNLKEGKKNVGLCKKIIAESESFSESLSLLGMKKEKIFVEALKSTIND
                     YYSVVDIEELKSKDKIVITTPYSYISSNIDRSIQIWVDIGSNAWNMKIEKDISNLIVL
                     RKSFEEKKIYTNEMEEYYKKYYLYNTVYNLLLNAKKIYAFKSEYAINGYIQESILYSI
                     LLKISHKGDKNYD"
     gene            7226..9445
                     /locus_tag="KR231_000569"
     CDS             7226..9445
                     /locus_tag="KR231_000569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent helicase"
                     /protein_id="HBH0002983.1"
                     /translation="MININYREDQIPIINYDNGTMAVPAVPGAGKTFIITNLVAKLLL
                     EQKHKSGKILILTYMNSAVNNFKGRIRKILEENKIDDTNSYEVMTIHSLAVKIIKEKP
                     EVVMLSEDFNIADDLQKSIILNECISRFRFEGGERAFRWFLKEQKDERWKEITLEAWE
                     RGFFEFAGNAISELKYKGISPDKLEEILSRGHKGMLKIILPIYKLYDRKLKQNGLLDY
                     DDILILAEKTLSLDEGLRKKFQTRYKYIFEDECQDSNEIQGNIIKIISSENKNLVRVG
                     DINQSITGTFSSSDPKFFKEFINSADFCYRMDMSNRSSKDILDLANTLVKYVTKEFRQ
                     EECRHALEDMQIKTVPNGMGYKENPNPEHYNINVKWYESWKIEIEQTARYVKGIKNKY
                     PDKSIGILVPFNEQVTQVAKELRENNLTFEELGPNSLNKRKVINNIAYIIDFMLHCDD
                     VEKLIVVLNKVFIDTDNEEEIKYFLEELKNYSTEEIIYNFEFSKLDNDLIEFKEESDI
                     YLSFKRGIDIIKQILEYPIIRLDLLVLFIGKKLSLEKEDKAVLDYISFYIKYLVSENI
                     NMDLEDVYNLLFDVKNRVFNHIIDVVYEINGYEPEPGSITLCNYHKSKGMEWDCVFLL
                     GLVEYNFPDNINQKFQSDKWYLKEKYKNPMAIIKSEVEAILKGSISTDYAHKTKIDSI
                     NEKIRLLYVGITRAKEMLVLSGSAYRDESDIGNKRKEQKPCIYLSRLNQHIIEKRSN"
     gene            9554..10384
                     /locus_tag="KR231_000570"
     CDS             9554..10384
                     /locus_tag="KR231_000570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PD-(D/E)XK nuclease family protein"
                     /protein_id="HBH0002984.1"
                     /translation="MNDKLKYFSYSQNSINTYKSCPLKFKYKYIDRINWKNDDVGSRE
                     YYETLKTGRDFHLICERYFSNIPLGIYFNEDDKNSKKFLKWMENIKKVVPIEKGKTYL
                     PEYEVRMTLNGDIIQAKYDLVVIGNNNIEIWDWKTESKKIDYKHVENRIQTIVYMFLA
                     KEVIPKVLKMDINVKDINMRYYQPEFDDLPITILYDEEKHEANRNKIQNYISMIKNTN
                     YEEHTYEDNLYNDIEKVYNKEERMCYRNKKHCKYCEFNKLCNGKEIDYSILEAEIYGT
                     "
     gene            10374..13841
                     /gene="addB"
                     /locus_tag="KR231_000571"
     CDS             10374..13841
                     /gene="addB"
                     /locus_tag="KR231_000571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase-exonuclease AddAB subunit AddB"
                     /protein_id="HBH0002985.1"
                     /translation="MGLRFVLGRSGSGKSTYILDEIKKEAQKNETTSIILLVPEQYTF
                     EAENRVSKLFLGKEKDKYLRVRVLSFKTLSNIVFSQVGGLTDVNINSSGKAMMVYRAI
                     EDVSEELNVFSKSKSQSGFVSSITDMISEMKQYNISPEMLENISGELDNETLSLKLKD
                     ISKIYNSFEGKLHENYVDAQDMLTSLASKIELSSYLDGACVYIDEFTGFTPNQYNVIK
                     SILNKSKSVNISLTVDDINYIGYSKSDMFSRTKFTYSKLTQLCNEEGIKILPQVNLNT
                     GVIKRFEKVKELQHLERFYNAYPYKIYSNQTENIKIKEFNNLYSEVEEIAREIVHLVR
                     DKNVRYRDITIATRDLNRYDFLVHSIFNEYNIPNFIDKKREAKSNPIVILIISALEMK
                     NRRYGYETMFRYLKSGLIGIDNDDINLLENYVLANGIKGKKWFDEKWDYRITQSLSGQ
                     ESEFELELKEKINEIKNRVLEPIVILQEKLRGKNRVKEICRYIYEFLLDINMPETIES
                     LIINFKDKGELDVANQYSQVWDIVVDILDQMVELMGDEIISLEKFIKLITLGFDEYEL
                     GLVPPSIDQVLVSSVDRMKNPDTKYLYLVGTTDGVFPLITKDSGILSDNDRESLGNKG
                     IEVDIDSKTRSFEEQFLVYKALTSTSKNLTITYPISDHEGKTLRPSIIISRLKKIFPN
                     IENKSYLVEENKSTDKDILKKITVKSPTFNELINVIKNYDSDGYNTEEINSIWLDIYR
                     YYLKDEIYSSITKKVIKGLSYTNQVHKIEEKKIRSLYKSNSLSISRLEKYAECPFAYF
                     IQYGLKAKKRKEYSFTPPDLGTFIHNILDRFSKELLQDNLTWRDIDEKYIELKIGIIV
                     DEIILKIPGYILNSSERYKYLAYRLKNMLTTAITIISQQIKQGSFEPIDYEVKFGNNG
                     KYPPIKMVLENGQEVSLIGQIDRVDEFEEGENKYIRIIDYKSGNKSISLTEIYYGLQL
                     QLLVYLDAILESAKDEDININPAAILYCRINNPIAKFNEDKDDEEIQEAILKELRMKG
                     LVVKDSHIVKEMDKSLIDGERKNSLVIPVGLTKDGNVGKSTSAISYEDFKLLRKYVRH
                     AIKDLCEEMLSGEIRIAPYKHKDGTSCDFCDYSAICQFDSTIKDNKYKNLNNKSNEEI
                     IKMMKGDVN"
     gene            13841..17668
                     /gene="addA"
                     /locus_tag="KR231_000572"
     CDS             13841..17668
                     /gene="addA"
                     /locus_tag="KR231_000572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase-exonuclease AddAB subunit AddA"
                     /protein_id="HBH0002986.1"
                     /translation="MSSPKWTKEQLEVIESRECNLLVAAAAGSGKTAVLVERIIQMIT
                     SRENPIDIDKLLVVTFTNAAASEMRERIGDAIGKALDENPENKHLQNQLVLLNKSSIT
                     TIHSFCLDVIKSNFHRINLDPNFRIGDQTECAILKQEAIEEVFEDLYEERDEGFLNLV
                     ESYAERGGDKEVQDIILGIYSFAMASPEPKKWLIDSAERFNIDENFDFSQSIWARAIL
                     DTVKIEINGLCLNMERALKEVESIEELETFAEKLSVEYKKIADISQACNKSWDEAYKK
                     MASMSFENYVKGVKRISKDAPSYIKESKEKAKTIRDKTKKSLESIVSATFNKDNDSIR
                     EEIKYLYNIVKPISSVVLRFEEEYSNKKREKGIIDFNDIEHFALNILTDVDEKGNIVP
                     SDIAVGYRNKFYEIFIDEYQDSNLVQEVLLKAVANTETPNRFMVGDVKQSIYRFRQAK
                     PELFLQKYNNYNDKKGSSHRKIMLYKNFRSREEVVDAVNYIFENIMNENIGEIEYTEK
                     ERLNLGANFNVDTDEKSIIGGATEIHLIQKDNKLDDDIINDKDDRINNKENEIEEEEK
                     LDNIQLEARMVGNIIKDLMKVNEDGKIQKVYDKGIDGYRPVEFRDIVILLRATSAWAP
                     VFADELMNMDIPTYADVGVGYFDTIEIKTILSLLQIIDNPMQDIPLISVLKSPIFGFT
                     PEDLIDIRVQSKDKIFYEVLKSTAEYDGFTDSQNENESEFIPSEECINKSKDFLIKLK
                     EFKEKSMYMSTDEFIWYLYTRTGYYAYVGALPGGSQRQANLKVLFERAKQFEETSLKG
                     IFNFVNFIEKLKKSSSDMGSAKTLGENANVVRIMSIHKSKGLEFPVVICSAMGKNFNT
                     QDFKKSILYHHNLGYGPQFVDYERRISFPSIAKEALKSKINIENLSEEMRVLYVAFTR
                     AKEKLIITGSTRNIQDSIKRWSNGIESLDTISQYEILKGKNFLDWIMPCVLRHRDLSN
                     LLEEVGLDAVFNVEHNSKWYGKLWNKSDILVEKKSDEEKESIEEILEKIDVDNPDSDY
                     YSEIEEKLNYIYPYEFSTRKPATISVTEIKKIQNNYEEELINTIFEQKVILKKPLFIQ
                     NEEEREKISGTERGTIVHLVMEVLDLKNVSSVNDIKSQIRGFVSKGIITEKQASIVNP
                     YKIYKFFASNIGKRMLNAEIINREKSIYAQVNMKDIYIYEKLINNDDKKLYDNESVML
                     RGIVDAYFEEDNQIVLVDYKTDFVNEENINQIIEKYKKQLDLYADIIETLTGKSVKEK
                     CIYLFGVDEAVCY"
     gene            17714..18925
                     /locus_tag="KR231_000573"
     CDS             17714..18925
                     /locus_tag="KR231_000573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exonuclease SbcCD subunit D"
                     /protein_id="HBH0002987.1"
                     /translation="MRFIHTSDWHLGKSLEGHSRIEEQAKFCEEFIKIVESNEIDMVI
                     IAGDVYDTSNPPAQAEKLFYQTVSRLANNGQRCVLIISGNHDNPERLSAITPLAHEQG
                     ILIYGYPLSATIEAKYKGFEITYATQGCTKLNINGENIVVATLPYPSEKRLNEVFSSE
                     DEFEKQKNYSEKVGDIFRSLEENFRSDTINIAVSHIFVIGGESTESERPIQLGGSFLV
                     ERKDLPEKAQYTALGHLHKQQKASERLNAYYSGSPLQYSKDERAYTKGAYIVDIKAGE
                     KPIIEDVYFNNYKPIEVFKCNGIEEALDICEQNQDREIWSYFEINTDEIISQNEIKKM
                     KELLKDIIEIKPIITSCYEQESVDIKEKSMAELFREFYSFSKGVEPKGELMDLFLDII
                     SEEGESADETN"
     gene            18912..22439
                     /locus_tag="KR231_000574"
     CDS             18912..22439
                     /locus_tag="KR231_000574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HBH0002988.1"
                     /translation="MRPIRLELTGLNSYIDKQVIDFEKLIERGLFGIFGTTGSGKSTI
                     LDAITIAMYGNISRNTKEYINSVCDKAIISYEFEIGSKNTRRRYIVDRTIARSKTGTK
                     TSNARLIEVLNDNTQNVLADKVVEVNEKVAQVVGLTANDFTRSVVLPQDKFNEFLRLS
                     RADRRDMLERIFNLEKYGRSLGEKVKKRKNIQLQNLKDLKSKLSQYDGITEEVYNNIN
                     QELIELKNLEKDKNNALDLAQKSYEESKTVYEEQLKLEKNELRKNELDLKNSEIKEKI
                     ALVENDSNAKKVDPYISSVQNLEKKIDEDSFAVSNLEKKLAILNQELEVTKNRYEKIN
                     KIKNEEIPKLSEEKIRLQQAIKLEEELVLLDRELKELKESGINLNKTKVELEKVKQVS
                     ESRKDAVTKSIKEVEGKIDKVNISAELKQKIFLAYEYEKDYNNVLEEKNQKLNKLEEI
                     LKETENINLKVRYIDKDKNDVNRNLENLSLHLDVLLKKCPGKSADLLLKSEYVTELRN
                     KANNTKENEIKKSSIQDELKIILESKFNTEREVNLLNEKLENNRKNRDDLEKELEELK
                     YLNLASELRRELKENMPCPVCGSKHHENHDITKYDENISFVKEKLEKLEKEKISIRNN
                     IEELNAKVSGYLSIEKMKTKELEDVKGKLGGIPSSQLLKKLDEEQRKLALLKSNIQEW
                     EKEKESTENKVTLAKEEKNKIEKEELKIRESLNNYKKLTRDLNIEIEGLENKCKKLKQ
                     EYLGLKTITKVSNLLSKVKEIRENEKELELLSTGHSNLLKNRDSLDIKIRENESKLHE
                     IEIELIKARELYVEKKLSRDNKYKEVISITKGDLAKNLLHNVEENICKILEQEESSKK
                     KLEEQRLEYEKNIAEKHNIDGRLKTAKEQYKDQKSTLNKLLAENKFESIYAVKRALLD
                     TDAVKKLIEEILEHEEEQKLLSFKIKSSKEKLNGRSIKKEYFEQLKDEIYNLKVEIGN
                     ISKDIGANQNQLITLKDSLDKINDFNKQLKVVEHNVDLLEELDKCVQGNKFVEYVSTN
                     QLKYIALEASKRLDGITKGRYALEIDSTLNFVMRDNFNGGERRSIDTLSGGETFLTSL
                     SLALALSSQIQLKGSAPLEFFFLDEGFGSLDSELLEIVIESLERLHSNNLSVGIISHV
                     EELKNRVPVKLLVSSSEAGIGSKVKIEYS"
     gene            22570..23823
                     /locus_tag="KR231_000575"
     CDS             22570..23823
                     /locus_tag="KR231_000575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyC/CorC family transporter"
                     /protein_id="HBH0002989.1"
                     /translation="MLESPNNLIQIIFLIVLLIGSAFFSASETALMSLSKIRIRYMQD
                     EGVKGAKLVSSLIENPNKLLSSILVGNNVVNIAATSISTSLFIGLMGEKGVALATAVM
                     TVLVLIFGEITPKTIAANNSEKVSLLVSKPIKAIIFILRPIVWIFNIITNIIFKLFGI
                     TNKGAKSFITEEELKTMVNVSHEEGVLEMEEREIINNVFEFGDMQAKNAMVQRIDMVA
                     IDMEDSYDEIIQVFKTEKLSRMPVYEETIDDIVGILNIKDIIFLSDEEIESFDIKNYM
                     REPFFTYEFKKITQLLEEMKLEKSQMAIVVDEYGGTSGLLTIEDLVEVIVGDIEDEYD
                     EEEDEIQVIKEDEYIVDGSTKIGDVNELIGVNLESEEFDSIGGFIIGHLSRLPEENEV
                     IEVDNIRFCIESIEKNRIKKIRIYT"
     gene            23972..25024
                     /gene="ytvI"
                     /locus_tag="KR231_000576"
     CDS             23972..25024
                     /gene="ytvI"
                     /locus_tag="KR231_000576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sporulation integral membrane protein YtvI"
                     /protein_id="HBH0002990.1"
                     /translation="MSILENNFLYKLKNNTIFFCIYTLLFIFIYKAFPYIAPFFLGAI
                     IALMINPISQKLENKFHINKGISTLVLSFLAVAIVSTVTTIIVINSMKELMGFLNNIS
                     ANPEDISNTIMYFLNKINDFMKSFQEIANFDVEQLVNKFSGEVMQITKNLLTSILGLA
                     TSIPYIIIFIITLFIATYFIAKDLDKIENSFYNMFTVDVRKKVKNVKKEAGLSLVGYI
                     RAYTILMAITFFAIWGSFALFGLKYGLIVGFVGALMDLIPFLGIITIYLPVIVYYFLI
                     KNYFIAISMTVIFFVLSLIREILEPKLVSVNVGLNPLATLAAIFIGIQVKGIIGVIFC
                     LGLVCMHDILKKVDIF"
     gene            25114..26340
                     /gene="pepT"
                     /locus_tag="KR231_000577"
     CDS             25114..26340
                     /gene="pepT"
                     /locus_tag="KR231_000577"
                     /EC_number="3.4.11.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase T"
                     /protein_id="HBH0002991.1"
                     /translation="MKQKVVERFLKYVSFDTTSNSQCENCPSSEGQRVLAKYIVEELK
                     TMGVDDVSLDENSYIMATLKGNTDGVDTIGFISHLDTIEDVSGKDIKPKIIENYDGKD
                     IVLNEALNVITYVKDSPELEEFKGDDLIVTDGTTLLGSDDKAGIAEIVTAIEYLINHP
                     EIKHGDIKIGFTPDEEIGRGADLFDVEKFGAKYAYTLDGGIVGELECENFNAANATIT
                     IHGRNVHPGSAKNKMVNAIHIAAEISEMFPADERPETTEGYEGFWHLNSIGGNVENVS
                     MAYIIRDHCKEKFENRKSIMIENIEKINKKYDNRVELDLKDSYYNMKEKIEPVMFIVD
                     IAKEAMEELGIKPRLVPVRGGTDGARLSFNGLPCPNIFTGGLNFHGKNECIPVSSMEK
                     ATKLIVRIAEKYAERV"
     gene            26547..27599
                     /locus_tag="KR231_000578"
     CDS             26547..27599
                     /locus_tag="KR231_000578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp18"
                     /protein_id="HBH0002992.1"
                     /translation="MKIKSKKIIAFALSLGIMLPSCVYADNISKNQNAQVDMNNYLQG
                     RKSPKEEKLIGEDRFDTAIKISQSGWNNGSERVFLVNSNSLPDALASTPLASKLDAPI
                     LLTNKNSIPYNVTEEIKRLNPAEVILIGSEGAISSSVKESLEDMEVLVSRIGGADREE
                     TSLLLTRQLDDTGDLGVSKVAVVNGYNGLADATSISSPAASDNTAIIYTGKDSIRSEA
                     KNFITQNSTKTYIVGGEYSISKKLEGQLVNSERLAGTDRKDTNAKVLEKFYGKSSKVN
                     NMYFAKDGSGREADLVDGLAAGVLASKTKSPVVLASGSLSSAQKSFIKKVKADKFVQV
                     GGGKNSKPYAEALALQ"
     gene            complement(28017..28586)
                     /gene="yfcE"
                     /locus_tag="KR231_000579"
     CDS             complement(28017..28586)
                     /gene="yfcE"
                     /locus_tag="KR231_000579"
                     /EC_number="3.1.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphodiesterase"
                     /protein_id="HBH0002993.1"
                     /translation="MKIGIMSDTHGSLLYFEKALNVLSDCDVLLHGGDVLYHGPRNDI
                     PEGYNPKKFIETLNKLENIVIVKGNCDADVDQMVIEHPIQSPYVMSQFGEIRIILNHG
                     YIESEEEIIDKAKKMGGDILVLGHTHVKKLYMDDNLIVINPGSTSIPKDGSHSVAIID
                     IIKTDDEDELELDINLIDINTGNIININD"
     gene            complement(28611..29411)
                     /locus_tag="KR231_000580"
     CDS             complement(28611..29411)
                     /locus_tag="KR231_000580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(+)/NADH kinase"
                     /protein_id="HBH0002994.1"
                     /translation="MKRIITINTNQLNKSLETKELLTRKLINAGFEVYSDIYPDTELI
                     ISIGGDGSFLRTVRDFDFPEIPIMGINTGHLGFFPDILPDKIDSFIEAYTKKDYIIQE
                     MSLLNAEVYTTTSGSNMLAVNEVVIRGDKSRTIHLNLSLDNKHIQNFSGDGMIISTST
                     GSTAYNYSAGGSIVDINLELMQITPLHPINTNAYRCFTSSIICSNESVIKIAPEYRFE
                     DSVLIVVDGVEHRFRQIENIKVSISDAKIKLLRMSNYEFWHRVSEKFL"
     gene            29546..30406
                     /locus_tag="KR231_000581"
     CDS             29546..30406
                     /locus_tag="KR231_000581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH0002995.1"
                     /translation="MFSIRNITKKLGKFKLNNINLELKEGDIVGIIGPNGSGKTTLIK
                     IIMGIIDADEGEIELCNETIENSPISFKNNIGFVYDSLQFYPHLKVKEFRKIVSLFYK
                     NFDRERFDEYLNKFDIEENMHIENLSKGQSEKLMLSSALSHNAKLLILDEPTAGIDPI
                     VRTEIMQYLQDFVKNGSSSVIISTHNTDNLIKIADYLVFINRGNQIFTVKKELIEQEY
                     KIIRANKAELEAIKESIVGVKEYKYYNEALVKVGDSLKVKSLLIEIDKHKVKNPTIEE
                     LMYYYVNEVR"
     gene            30406..31092
                     /locus_tag="KR231_000582"
     CDS             30406..31092
                     /locus_tag="KR231_000582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-2 transporter permease"
                     /protein_id="HBH0002996.1"
                     /translation="MFNLIRKDLIIGISSDGIRNLKYILLFFVFYFFLNSISYYTVSI
                     VVSYLIFINTFECDYENDSRIFIRSMPVSIEDIVYSKYLLGVGLIISVTIIVSLLSKL
                     TSLVFFRNMVLNDVFFSVNIFLAILTILLPLIFKFGYGKMKVCGFIVSILIYFVYGSL
                     LKMISMIVYQVKHFNYSKVGGVYLSNYVTDIANTKYINLYSMTFLTIIIFIISMYFSI
                     KISKKNKFNY"
     gene            31144..31686
                     /locus_tag="KR231_000583"
     CDS             31144..31686
                     /locus_tag="KR231_000583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0002997.1"
                     /translation="MKKFIKVSFFILGIFTLFIAINKLVYRDMVSVKDYEINHLEEIV
                     FDFDSRRSRDVGTIVRFKISNNSKYSYKLNSAKMKFENCVENKKGMNKCSAYVNVDLF
                     NEKNSITERTLKYGIKPNNQGYVDFVIPKGLNFDYRYFNESGMSVEYKGEYIVNIPMA
                     KGLYLVVGKNNDTWNANIME"
     gene            31765..32232
                     /locus_tag="KR231_000584"
     CDS             31765..32232
                     /locus_tag="KR231_000584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbaK/EbsC family protein"
                     /protein_id="HBH0002998.1"
                     /translation="MSISNVREYFKQFGKEDSILEFEQSSATVELAAEAAGVIPARIA
                     KTLSFKIGDDAILIVTAGDAKIDNKKYKAEFNCKAKMLTPEEVLEFTGHAIGGVCPFG
                     LKNSIKVYLDDSMKRFDTVFPACGSSNSAIELTCEEMEKFSKCEKWVDVCKNW"
     gene            32941..34077
                     /locus_tag="KR231_000585"
     CDS             32941..34077
                     /locus_tag="KR231_000585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA dehydrogenase"
                     /protein_id="HBH0002999.1"
                     /translation="MDLNSKKYQMLKELYVSFAENEVKPLATELDEEERFPYETVEKM
                     AKAGMMGIPYPKEYGGEGGDTVGYIMAVEELSRVCGTTGVILSAHTSLGSWPIYQYGN
                     EEQKQKFLRPLASGEKLGAFGLTEPNAGTDASGQQTTAVLDGDEYILNGSKIFITNAI
                     AGDIYVVMAMTDKSKGNKGISAFIVEKGTPGFSFGVKEKKMGIRGSATSELIFEDCRI
                     PKENLLGKEGQGFKIAMSTLDGGRIGIAAQALGLAQGALDETVKYVKERVQFGRPLSK
                     FQNTQFQLADMEVKVQAARHLVYQAAINKDLGKPYGVEAAMAKLFAAETAMEVTTKAV
                     QLHGGYGYTRDYPVERMMRDAKITEIYEGTSEVQRMVISGKLLK"
     gene            34136..34918
                     /locus_tag="KR231_000586"
     CDS             34136..34918
                     /locus_tag="KR231_000586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009524639.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="electron transfer flavoprotein subunit beta/FixA
                     family protein"
                     /protein_id="HBH0003000.1"
                     /translation="MNIVVCIKQVPDTTEVKLDPNTGTLIRDGVPSIINPDDKAGLEE
                     AIKLKEEMGAHVTVITMGPPQADMALKEALAMGADRGILLTDRAFAGADTWATSSALA
                     GALKNIDFDIIIAGRQAIDGDTAQVGPQIAEHLNLPSITYAEEIKTEGEYVLVKRQFE
                     DCCHDLKVKMPCLITTLKDMNTPRYMKVGRIYDAFENDVVETWTVKDIEVDPSNLGLK
                     GSPTSVFKSFTKSVKPAGTIYNEDAKTSAGIIIDKLKEKYII"
     gene            34937..35947
                     /locus_tag="KR231_000587"
     CDS             34937..35947
                     /locus_tag="KR231_000587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418892.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="electron transfer flavoprotein subunit
                     alpha/FixB family protein"
                     /protein_id="HBH0003001.1"
                     /translation="MGNVLVVIEQRENVIQTVSLELLGKATEIAKDYDTKVSALLLGS
                     KVEGLIDTLAHYGADEVIVVDDEALAVYTTEPYTKAAYEAIKAADPIVVLFGATSIGR
                     DLAPRVSARIHTGLTADCTGLAVAEDTKLLLMTRPAFGGNIMATIVCKDFRPQMSTVR
                     PGVMKKNEPDETKEAVINRFKVEFNDADKLVQVVQVIKEAKKQVKIEDAKILVSAGRG
                     MGGKENLDILYELAEIIGGEVSGSRATIDAGWLDKARQVGQTGKTVRPDLYIACGISG
                     AIQHIAGMEDAEFIVAINKNPEAPIFKYADVGIVGDVHKVLPELISQLSVAKEKGEVL
                     AN"
     gene            35966..36763
                     /locus_tag="KR231_000588"
     CDS             35966..36763
                     /locus_tag="KR231_000588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-CoA hydratase/isomerase family protein"
                     /protein_id="HBH0003002.1"
                     /translation="MSTSDVKVYENVAVEVDGNICTVKMNRPKALNAINSKTLEELYE
                     VFVDINNDETIDVVILTGEGKAFVAGADIAYMKDLDAVAAKDFSILGAKAFGEIENSK
                     KVVIAAVNGFALGGGCELAMACDIRIASAKAKFGQPEVTLGITPGYGGTQRLTRLVGM
                     AKAKELIFTGQVIKADEAEKIGLVNRVVEPDILIEEVEKLAKIIAKNAQLAVRYSKEA
                     IQLGAQTDINTGIDIESNLFGLCFSTKDQKEGMSAFVEKREANFIKG"
     gene            36861..37706
                     /locus_tag="KR231_000589"
     CDS             36861..37706
                     /locus_tag="KR231_000589"
                     /EC_number="1.1.1.157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxybutyryl-CoA dehydrogenase"
                     /protein_id="HBH0003003.1"
                     /translation="MKLAVIGSGTMGSGIVQTFASCGHDVCLKSRTQGAIDKCLALLD
                     KNLTKLVTKGKMDEATKAEILSHVSSTTNYEDLKDMDLIIEASVEDMNIKKDVFKLLD
                     ELCKEDTILATNTSSLSITEIASSTKRPDKVIGMHFFNPVPMMKLVEVISGQLTSKVT
                     FDTVFELSKSINKVPVDVSESPGFVVNRILIPMINEAVGIYADGVASKEEIDEAMKLG
                     ANHPMGPLALGDLIGLDVVLAIMNVLYTEFGDTKYRPHPLLAKMVRANQLGRKTKIGF
                     YDYNK"
     gene            37793..38968
                     /locus_tag="KR231_000590"
     CDS             37793..38968
                     /locus_tag="KR231_000590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000786547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA C-acetyltransferase"
                     /protein_id="HBH0003004.1"
                     /translation="MREVVIASAARTAVGSFGGAFKSVSAVELGVTAAKEAIKRANIT
                     PDMIDESLLGGVLTAGLGQNIARQIALGAGIPVEKPAMTINIVCGSGLRSVSMASQLI
                     ALGDADIMLVGGAENMSMSPYLVPSARYGARMGDAAFVDSMIKDGLSDIFNNYHMGIT
                     AENIAEQWNITREEQDELALASQNKAEKAQAEGKFDEEIVPVVIKGRKGDTVVDKDEY
                     IKPGTTMEKLAKLRPAFKKDGTVTAGNASGINDGAAMLVVMAKEKAEELGIEPLATIV
                     SYGTAGVDPKIMGYGPVPATKKALEAANMTIEDIDLVEANEAFAAQSVAVIRDLNIDM
                     NKVNVNGGAIAIGHPIGCSGARILTTLLYEMKRRDAKTGLATLCIGGGMGTTLIVKR"
     gene            39164..40066
                     /locus_tag="KR231_000591"
     CDS             39164..40066
                     /locus_tag="KR231_000591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HBH0003005.1"
                     /translation="MFKKENQRYNLISYTNEEEMTLKEVLLDKLNFSVRSLSKMKREK
                     SVLVNGVYKKPSLKVYSGDLIEVKIDEEKANFEPQDLNLQIIYDDFDIIMVNKPPFMV
                     VHPTKSHYDKTIANGISYYIDNQKENVKIRFVNRLDMNTSGLVIVAKNAYAHHTLSTA
                     MSENKVEKKYITVVDGIIKENEGTIDEPIYRPTEDSIKRIIDERGQSSVTHYKVIERL
                     ENATVLEVSLETGRTHQIRVHMAHIGHGIIGDELYGYVDEDLINRQALHAYKLEFEQP
                     RTKEKLKFKADIPEDMKELISKLR"
     gene            40080..41084
                     /locus_tag="KR231_000592"
     CDS             40080..41084
                     /locus_tag="KR231_000592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoid-associated protein"
                     /protein_id="HBH0003006.1"
                     /translation="MIIHKFIIHVLDKNSDVPILNDFEGKVNQEVDGFFQKAIKRIAK
                     DEDLRKGVFKDYNDNLIKNCCEQIIYDESTFLKNSKEIASYLFDVMKINAALESCDLA
                     ICLYTIKDEKSVAILKLDYKKLYTHSIEFVDDKFNIQMVSNEIGIPETLRQKQGALIS
                     LSGINDEFHLRLLDKDAEKEGSESKFVTEFLNAKKIDDDKYKTKVFKNTAENWITNAL
                     SNDIKQAEDVRSILNYTLKEKHEVDINDFVDNSIKDDELKDSFKEHMEEKGLDESFSI
                     DKKWVEKKLKKRSIKTDNGFDIKGNLTDFEDPMKYTVKQNQDGTIDIIIKNVTFYEEK
                     "
     gene            complement(41228..41455)
                     /gene="acpP"
                     /locus_tag="KR231_000593"
     CDS             complement(41228..41455)
                     /gene="acpP"
                     /locus_tag="KR231_000593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HBH0003007.1"
                     /translation="MFEKIKEIIAEQLGVDNLDEITMEASLMDDLEADSLDAVEIIMA
                     LEDEFGIEIPDEEAENFKCIGDICKYIEENK"
     gene            41627..42052
                     /locus_tag="KR231_000594"
     CDS             41627..42052
                     /locus_tag="KR231_000594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0003008.1"
                     /translation="MKYVGLLLTSVGMFLLIAVNFYYNSITLDMQRIEDYVMETNLIL
                     EDVAEKESYVSNEKEDYISRLMHVKKGIENSKTSFLIERYKEYKIKSIESLIYTISEE
                     KKDYLDEVDRYNKLGEKEINKLINKNFLEVTYLSITTYI"
     gene            42100..42306
                     /locus_tag="KR231_000595"
     CDS             42100..42306
                     /locus_tag="KR231_000595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0003009.1"
                     /translation="MTKLEDNMERFFGGCEGFFGNKMLIIIVIVFLLLCTDILEDLLC
                     DDNIWIWVILIVLLLFNFDDGCCC"
     gene            42488..42667
                     /locus_tag="KR231_000596"
     CDS             42488..42667
                     /locus_tag="KR231_000596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0003010.1"
                     /translation="MLDRFFGEEGCFGGGGWWIIVLFFLFLAFGDSWAEFDIMAWIPF
                     LIVLLILCCCGGCLE"
     gene            42701..42901
                     /locus_tag="KR231_000597"
     CDS             42701..42901
                     /locus_tag="KR231_000597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0003011.1"
                     /translation="MLDRFFGEEGCFGGGGWWIIVLFFLFLAFEDCWRDIDIMSWIPF
                     LILLLITCSCGGFFDGEVGCGC"
     gene            43154..44170
                     /gene="ccpA"
                     /locus_tag="KR231_000598"
     CDS             43154..44170
                     /gene="ccpA"
                     /locus_tag="KR231_000598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family transcriptional regulator CcpA"
                     /protein_id="HBH0003012.1"
                     /translation="MKGNITIKDVAKQAGVSISTVSRVINDSKPVTDEVKQKVLEVIK
                     ETGYIPNPLARSLVTKKSQLIGVIVPEVSDSFVNEVLNGIEEVAKMYDYDILLANTYS
                     DKEQELKSINLLRAKQVEGIVMISWIVEQEHINYIQNCGIPATYISKTARNYDIYTVS
                     TSNEEATFDMTEHLIKKGHEKIAFIMTSKDDTVLEMERLAGYEKALSNNNIELDKSLI
                     KYGGTDYESGYNSMKELLDDGIIPHAAFVTGDEAAIGAINAICDAGYKVPEDISVAGF
                     NDVKIARMYRPKLTTVYQPLYDMGAVAIRMVIKLINKELIENKKIELPYRIVDRESVT
                     ERKK"
     gene            complement(44293..44691)
                     /locus_tag="KR231_000599"
     CDS             complement(44293..44691)
                     /locus_tag="KR231_000599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0003013.1"
                     /translation="MKKLDTESLEKMAKQKNIDKDKIEKMADSYKGKSENELMEELIK
                     IGKNLDGRDEVVSKFKAFLDENQRKKLDNIMEKISDAENQRDTKPAKTKKAKPTKGKS
                     NSPAPKNTPGSQQKKSKSLFKKTKKSNPHE"
     gene            44903..45808
                     /locus_tag="KR231_000600"
     CDS             44903..45808
                     /locus_tag="KR231_000600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0003014.1"
                     /translation="MNNLLFLIGVIALSNGNISIFDDKNKSKGNNRVRKNKKNANDKL
                     SQSTHGNLRFDANDIKRGLRLMDLSEEDLEMGMEIITRTKKYMSRDERKILIKIESVL
                     DLVRGIKKLNNIDMVDTEDETDFFRKMDSDDKKNMMIKEIIDVFPEKRKNSVEKAIGM
                     KKKIDLFAELFLPDDFGEGGFSLSSLANINNLGSMNNLKLLGSLLRGDDSNNDDEDNN
                     DELNYEDEELDCEDKELDDDELTDEGEMEDNEDELVEDKNTGYENIENDEDIVYDEEL
                     YNINEQESEYNYNEKNTKTRAKKKR"
     gene            45923..46103
                     /gene="ssrS"
                     /locus_tag="KR231_000601"
     ncRNA           45923..46103
                     /ncRNA_class="other"
                     /gene="ssrS"
                     /locus_tag="KR231_000601"
                     /product="6S RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00013"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00013"
     gene            46286..47503
                     /gene="cdeC"
                     /locus_tag="KR231_000602"
     CDS             46286..47503
                     /gene="cdeC"
                     /locus_tag="KR231_000602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exosporium morphogenetic protein CdeC"
                     /protein_id="HBH0003015.1"
                     /translation="MQDYKKNKRRMMNQPMSTMNEEEVYTDEINSEDMRGFKKSHHHN
                     GCNTDNKCECHDDCNPCNPCNPCKPNPCNPCKPNPCDDNCGCHDNCKCDCEPCEMDSD
                     ECFENKCGPECCNPISPRNFSVSNAVPFAIEANRIFDTMQFQTFTDATGPNGEPLTFE
                     TEVVEVFGSVPSAGQASVTIEKICLSNDGIVIDTGMTTLEDFDLDPLGDIVGRNCETT
                     FEFAVCGERNSECCRQGKGKSVAYKQRGLTVAVRNLVLELRGRCGCTEFVALAFPAVR
                     AGGGCKRRVDYVEFTFNTLSAPICLPADGRAVTLRQEYQTNLTVDCIGKSILKLECNE
                     CCEPFYELIIPNDIDLVLCLQETVSTLISEQIVVLASPNPIQPRLVDTFSKVCDFSQC
                     GPNHGSGKPSCHR"
     gene            complement(47603..48925)
                     /locus_tag="KR231_000603"
     CDS             complement(47603..48925)
                     /locus_tag="KR231_000603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HBH0003016.1"
                     /translation="MKVPYLVLSTVILFISNFIVRIFGFLYKIFLSRALGETGLGIYH
                     MIFNFLMICLAVTTTGIPTALSCLVAKRKALNDRHNTNALFISTLYISFFVALIISIV
                     ASFNSSFLSLKFLKDAKLNLFILAVCPAIVIITLSNVLRGYYYGIKNVKIPAIGQIIE
                     QIGKILFVFLLVMYINNKSMNCYIALLGISIGELSNIIFMLICLWRDSSFDNRYIISI
                     KDFYNSSMETLKMSIPITCNRMSNILLQSISSMMIPSRLALSGMTYQQSLSMYGIVSG
                     MVMPFIFLPFTVGSALIVNLIPTISQEMALRKRKSVIKKIKYSILLTLFVGILSSIFF
                     YFFGKDLCILVFKNTLAGEYLKAMFLVPLFMSLNQTLSGILHSIRKELASSINTITGM
                     LIQLIALYVFLPIPGLNIYAYIYTMTIVSIFTCLLHTIVLFKSLKSIR"
     gene            complement(48976..49770)
                     /locus_tag="KR231_000604"
     CDS             complement(48976..49770)
                     /locus_tag="KR231_000604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidinol-phosphatase HisJ family protein"
                     /protein_id="HBH0003017.1"
                     /translation="MFYDYHMHSSFSTDGKSTMEEMVKKSIELGLEEICFTDHVDYDV
                     YADDSFSIVYEDYFKSLETLQSKYKDKISIKKGIEFGVQTQLMDTYKKEAHQYPLDFI
                     ICSIHAIDTMDLYLGNYFKDKTQHEVYENYYLYLYNIVKNYKDYSVLGHLDLIKRYAP
                     YDTILDDRLFSDIIEETLKQAIYDGKGIEINTSCYRYNLPDLTPSKYILQMYKDLGGE
                     IITTGSDSHHISQVACEFDYIYSLLKNMGFKYVSKFNKLKPEFIKL"
     gene            49880..51325
                     /locus_tag="KR231_000605"
     CDS             49880..51325
                     /locus_tag="KR231_000605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HBH0003018.1"
                     /translation="MEKYRIDLNEKKSTKYIQIFNHIKELIINKELVEHEKLPPIRKL
                     SNFLQVNNTTIVKVYELLENEGYVYKIIGSGTFVSSLNSYKSGIDNRKNKIIVQREDL
                     IHFDNGNPSNDMFPIDSFKNAVNMALSKDGSSIFEYDEGLGSEELREKMVEYLSDGNI
                     KTTKENIQIISGAQQGIDIVCKGLISYSDVVFMEEPSYNGAIEVFKSRGAKIISIPML
                     DDGIDIGILKLKLEKIKPRLIYIMPNFQNPTGISYSTYKKKKLIELAEEHDFYIIEDD
                     FISDFVFESKDNRTIRSYDDKNRVVYIKSFSKILMPGLRIGIVEMPNELLKKVLWAKY
                     SSDISTPGLIQKSMYYYMNNFDWKNYLSHIEKIYTDKYKLAKNLINDKLSGKLKVRKS
                     CGGINFFLELPRGYTSQAFTNFMLNKGVSMLPGTYFFDNLVDDRFFRINIARPSMEEL
                     EKGISIISDNIDEFFCEYKNKLDIKSNKLFY"
     gene            51354..51563
                     /locus_tag="KR231_000606"
     CDS             51354..51563
                     /locus_tag="KR231_000606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF896 domain-containing protein"
                     /protein_id="HBH0003019.1"
                     /translation="MFDKKKLDRINELAKKNKEGILSADEIKEREILRKEYLENFRAH
                     FRSRLDSVKVVSPEEYEQYMKNNKN"
     gene            51583..52977
                     /locus_tag="KR231_000607"
     CDS             51583..52977
                     /locus_tag="KR231_000607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase"
                     /protein_id="HBH0003020.1"
                     /translation="MNLKYEFKNAWDFERKENTIEQIMQYSSNYMEFLSKSKTERLSV
                     KEIIKLAKENNYISIDEAMEKGSISCGDKIYVINKEKAVALFVIGKNYIEKGMKIIGS
                     HIDSPRLDLKPNPLYQESNLGFFKTHYYGGIKKYQWTAIPLALHGIVILNDGTKVDIS
                     IGEEDSDPVFCVTDLLIHLAGDQMQKKLSEGISGEALNILIGNMPLEDEEKEPITANI
                     LKILNEKYNIVEEDLLSAEIEVVPAGKARDLGLDRSMVLGYGHDDRVCSYAAVKAILE
                     TEQPEFTSVALCVDKEEIGSKGNTGMHSKFFENTVAELIALEGDYCDIKVRRALANSK
                     VLSADVSAGYDPNFGEAYEKRNSAYMGNGVVLTKYTGSRGKSGCNDANAEFMSEVKRI
                     FNKGNVVWQTAELGKVDQGGGGTIAHILANQGAEVIDCGVGVLNMHAPHEIVSKVDIY
                     EMYKGYKAFFNINL"
     gene            53217..53402
                     /locus_tag="KR231_000608"
                     /pseudo
     CDS             53217..53402
                     /locus_tag="KR231_000608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896033.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
     gene            complement(53511..54677)
                     /locus_tag="KR231_000609"
     CDS             complement(53511..54677)
                     /locus_tag="KR231_000609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017752472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HBH0003021.1"
                     /translation="MKGGVRKRGKKWYYYFDAGIVDGKRKKVERVGGNTKKEAEKSLR
                     DAINEYENAGIVFDETNMSLSDYLNFWYKEYVLLNCKYNTQESYRNLIENHIEPRLGK
                     CKLKSINPAIIQEFLNNKSKETYTQNGEEKHYTKGVLKAIYVVLNAALKSAVYPYKLI
                     KENPVQYASIPKNVLKVKNESDNKTITLDEFNKILEIYPKNTNIYIPLLIGFHTGMRK
                     GEILGLCWDNVDLDNNIIKVRKNLIKRKVSEFELASPKTKTSIRDIKIGDTLSRILKE
                     EKLNQKKQKIKIGKWYKETEYDWVCRKKDGSFVNHNNIDAAIRTINKKLNINFNFHCL
                     RHTHATLLLENGANVKYIQQRLGHSQLSTTMDTYSHVTSKMESETIDILEGILQ"
     gene            complement(54815..55021)
                     /locus_tag="KR231_000610"
     CDS             complement(54815..55021)
                     /locus_tag="KR231_000610"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0003022.1"
                     /translation="MNLSFNKKKKFELSKEELELIENWLGNKYAGDMTIPAIVDFSLE
                     TDIEYEKIVVYLAEKVLESRDKKH"
     gene            complement(55080..55301)
                     /locus_tag="KR231_000611"
     CDS             complement(55080..55301)
                     /locus_tag="KR231_000611"
                     /inference="COORDINATES: protein motif:HMM:NF024835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBH0003023.1"
                     /translation="MLKELRKKKKLTQIELAKRVGCHRSQISRLENNENKDLTIPALI
                     ELEIALGLEEKYLVNYFADEYIKKRKLHK"
     gene            55585..55722
                     /locus_tag="KR231_000612"
     CDS             55585..55722
                     /locus_tag="KR231_000612"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0003024.1"
                     /translation="MNKTKYYDILKLNLLMKKLKELDKNKINEYKIKVKEIHKINKKE
                     E"
     gene            complement(55759..56154)
                     /locus_tag="KR231_000613"
     CDS             complement(55759..56154)
                     /locus_tag="KR231_000613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBH0003025.1"
                     /translation="MNRIKELREEKGISLDKLSEDLHINKSTLSRIENGLREPKKSTI
                     EEYANYFDVSTDYLLGRTDVRNSLFINKNEKDYDAENFKTEKELIENMYLDEDMKEVF
                     NIFSELSPDAREKALKVAELFLLDEKNKK"
     gene            56333..56566
                     /locus_tag="KR231_000614"
     CDS             56333..56566
                     /locus_tag="KR231_000614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF739 family protein"
                     /protein_id="HBH0003026.1"
                     /translation="MYLNRLEGLMKENRHTQKNVADILGLSSYGFRLKLKGKNEFKAS
                     EIKKISKLYNVSADYFFSDEVAKIAIKEERGNK"
     gene            56566..57318
                     /locus_tag="KR231_000615"
     CDS             56566..57318
                     /locus_tag="KR231_000615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rha family transcriptional regulator"
                     /protein_id="HBH0003027.1"
                     /translation="MKNLTIIKQNNQFLVESREVAELIEKKHDNLLRDIRGYKKILED
                     SSNLKSQDFFIESTYINTQNKIQPCYLLTKKGCDMVANKMTGEKGIIFTAIYVTKFEE
                     MERELKEQQPKLPTTYKEALQQLLIEVEEKEQLQLENQVMKPKADYFDALVERNLLTN
                     IRDTAKELGVKEKTFVLWLIEKKYCYRDLKGKIKPYSNKMQYFELKEFTTPYGHSDTQ
                     TLINPKGREAFRLLLIKDGLVKEKEYQITLLG"
     gene            57363..57617
                     /locus_tag="KR231_000616"
     CDS             57363..57617
                     /locus_tag="KR231_000616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0003028.1"
                     /translation="MSEDIFYGIKNTLDEIAEVQIKNKQGVLKEVGMLISGEDNSCIT
                     HCLDEDLIKFYIKEEAVLTIDKDSHLLCMLDALFYNFLDK"
     gene            57645..58088
                     /locus_tag="KR231_000617"
     CDS             57645..58088
                     /locus_tag="KR231_000617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015984880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBH0003029.1"
                     /translation="MKKLGNISNFNLDKQEDKSFNDLDNISICFSEGIRKVVEMNLNN
                     YKNKISKYLNETSKIELLEPKELTIVISKGYPDYLMSVEEASKRLKIDKVFGYELIKN
                     GLLKSVDIGATKVSSYELDDFITRNQGKNIKEMLREMKELREGVI"
     gene            58216..58404
                     /locus_tag="KR231_000618"
     CDS             58216..58404
                     /locus_tag="KR231_000618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0003030.1"
                     /translation="MKIIYKNKVYKVEQDKKLFRITYYDEQRGSKKFNKEKKIKRSVL
                     TRDIELVNLYLPAHLKIK"
     gene            complement(58539..58709)
                     /locus_tag="KR231_000619"
     CDS             complement(58539..58709)
                     /locus_tag="KR231_000619"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0003031.1"
                     /translation="MSNKDIYTREEDKRFTLRINKLLFEKIEQLAQKDKRSIGREIEF
                     ILEKYFEDNPLE"
     gene            58852..59010
                     /locus_tag="KR231_000620"
     CDS             58852..59010
                     /locus_tag="KR231_000620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Arc family DNA-binding protein"
                     /protein_id="HBH0003032.1"
                     /translation="MTNERVRFTFRLPAPLLEKIKNRASIEGSSMNSLILHILWDYIK
                     EIENKEVK"
     gene            59010..59237
                     /locus_tag="KR231_000621"
     CDS             59010..59237
                     /locus_tag="KR231_000621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0003033.1"
                     /translation="MVELVKEFDLQTIKVGNAVKVNCKRFGFEIDCIVVVATEKELNL
                     AYFDEGRGCMEYQALITEDIQDGDYEIKILS"
     gene            59335..59649
                     /locus_tag="KR231_000622"
     CDS             59335..59649
                     /locus_tag="KR231_000622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0003034.1"
                     /translation="MESLKRIKKMVQKQLVLAELEINKNSKLYEELENKDRGLIDDIH
                     MREYLREKVAWERVKYAIENILGGINLEIKSKEHEESEDYKIFQLILEELERDKPIDV
                     QI"
     gene            59733..60242
                     /locus_tag="KR231_000623"
     CDS             59733..60242
                     /locus_tag="KR231_000623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="siphovirus Gp157 family protein"
                     /protein_id="HBH0003035.1"
                     /translation="MSTLYELTTDLLEIEEGLTETTGNETEKLEEIKEIIKQEIQNKN
                     TRIVSVILNIDSDINSIDSEIKRLQELKRVKKNTLDRLKSNIKDCMELLGTKKVETVL
                     GNISIRKSAGSLVIEDEEKIPAIYKTVEQVVKVDKNIIKDFIKKGHEVEGCRIEYGTT
                     LTIPKAKKE"
     gene            60252..60860
                     /locus_tag="KR231_000624"
     CDS             60252..60860
                     /locus_tag="KR231_000624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015984885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ERF family protein"
                     /protein_id="HBH0003036.1"
                     /translation="METNNVYIKLVNIQSTLKAPKSQFNSFGKYNYRSCEDILEGLKP
                     ILKEEKALVILDDNIVQIGNRFYVEATATLIDAETGEKVSTKALAREDETKKGMDLAQ
                     VTGSVSSYARKYALNGLFCIDDTKDSDATNKHGNEQKKKEVNESELNTLYSLGESIEK
                     DKNRVDSEVYKKFGKLAVDLTKQEYEKVLNGYKSILEKQKQE"
     gene            60870..61751
                     /locus_tag="KR231_000625"
     CDS             60870..61751
                     /locus_tag="KR231_000625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016056364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaD domain protein"
                     /protein_id="HBH0003037.1"
                     /translation="MGIIRVSKDKDNPYVVLNKTCLEDVKLSWQAKGLHSYLISKPDH
                     WKIYVNDLCKRSKNGRDATANILKELIENGYITRKPCRDSNTNKMLGGYDYEVYEIPL
                     ENPQKLKSRKTDFPETGFPGNRVSRKPENTEVVSNDFKVNNDITTIVINEQSNKDKTT
                     YIKKYFEKYIGVITPNNFIELMSYLDDGMEADVIIRAVDEAVGSGVKNYKYVKTILNN
                     WIEAGVKTVLELTEYQNEFERKKKSKQEKKQSNSKTVNTHNVNKNKFANFNQTFTQYE
                     EKELDEIIKKSQKEKFK"
     gene            61812..61985
                     /locus_tag="KR231_000626"
     CDS             61812..61985
                     /locus_tag="KR231_000626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="resolvase"
                     /protein_id="HBH0003038.1"
                     /translation="MARIYAQRSGSLNEQDRLELLRLLGKAGYTVKVAREKQNSKTTY
                     TYFVEYTEEQEEK"
     gene            62001..62408
                     /locus_tag="KR231_000627"
     CDS             62001..62408
                     /locus_tag="KR231_000627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HBH0003039.1"
                     /translation="MNTITLVGRLVADAELKYLPNSGTPKITFSMAVDRRFKDKNGNK
                     ITDFIQCEQLGKHVENLVQYLVKGKPIYAVGELNIYNYKDENGCWKSITKVNVNALEL
                     LSSKNDNNAKQEYVPPGLDPQGFQAIDDDDIPF"
     gene            62482..62676
                     /locus_tag="KR231_000628"
                     /pseudo
     CDS             62482..62676
                     /locus_tag="KR231_000628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861747.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            62728..62985
                     /locus_tag="KR231_000629"
     CDS             62728..62985
                     /locus_tag="KR231_000629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0003040.1"
                     /translation="MIIIRSQDKTDLVKADWINVDKECVYAMFGDMDNFKKIGEYEDE
                     KRAIQVLDNIQRFIEGGTRTDSIDSYKVRSYRNRIFQMPVK"
     gene            62999..63364
                     /locus_tag="KR231_000630"
     CDS             62999..63364
                     /locus_tag="KR231_000630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015994375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0003041.1"
                     /translation="MLKVEKYFSGSLGTNIIDDDPTCRNYLALYCCVHGVRKNGELIF
                     PTCEKMLIEFNVDKNRKKKKKGSKVKLINAKTGEEKIFDSIDSAACFLRLQSQAVYQT
                     IKKKTKTRSGWKAEYIEEE"
     gene            63482..63817
                     /locus_tag="KR231_000631"
     CDS             63482..63817
                     /locus_tag="KR231_000631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015981539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0003042.1"
                     /translation="MNILASVILVIGSFIAGRVYEYRLNLNENDEADSKVLLDVFNEI
                     SVLREENKSLKEKLQEKELLFINRLIDFLHDKKICECCIYDCKIDDIEYDCEDGIKKW
                     LDSEELIFE"
     gene            63925..64998
                     /locus_tag="KR231_000632"
     CDS             63925..64998
                     /locus_tag="KR231_000632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA cytosine methyltransferase"
                     /protein_id="HBH0003043.1"
                     /translation="MLTFLDLFAGIGGFRLGMEKAGHKCLGHCEYDKFANLSYNAMHK
                     PKEDEWFERDIREIRTENIPRADVWCFGFPCQDISVAGKQFGFRGERSSLFFTVTKLI
                     RELKEEDRPKYLLIENVKNLLSVNGGFDFLKVLVELDEIGYDAEWQVLNSKNFGVPQN
                     RERIFIVGHFRGRSTRKVFPIERKSRKNLEQLNNPTHSTNRIYDAVGIARCIRSQAGG
                     GGAKTGLYFIDLNKNSKVTINARCLKAKYNAGVTNRNCDNSGVLVNAVLTPDRVNKRQ
                     NGRRIKESGETMFTLTAQDKHGILKNGDIRRLTPKECFRLQGFPDKYYERAASVCSDS
                     QLYKQAGNAVTANVVYEIAKRMG"
     gene            65078..65287
                     /locus_tag="KR231_000633"
     CDS             65078..65287
                     /locus_tag="KR231_000633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0003044.1"
                     /translation="MYEYILRWQIGLSLENRKIHYTYGSKEALRKKAKALAKDENIVL
                     ITIDKVDEVIKNTISEKIIERFENL"
     gene            65299..66303
                     /locus_tag="KR231_000634"
     CDS             65299..66303
                     /locus_tag="KR231_000634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoid-associated protein"
                     /protein_id="HBH0003045.1"
                     /translation="MIIHKFIIHVLDKNSDTPILNDFEGRVNQDMVLFFQKKISKVSR
                     DNDIRTAVFNNYSNNLIKKCCEQIIYDESSFLNNSKEIAAYLFDVMKLNATLESCDLA
                     ICLYSQKDEKKVAILKLDYNNSYTHSIEFKDDKFNIQMSKNEINIQETKTVKIAALVG
                     LSGMNDKYHLRVLDKDAEKEEANSKFVTEFLNATKIKDDKYKTKKFKNTAENWITNAL
                     SNDIKQAEDVRSILNYTLREKHEIDINDFVDKTIKDDKLKDSFKEHMEEKGLVEGFSI
                     DKKWVDKKLKKRNIKTDNGFEIKGNLTDFEDPMKYTVRQNQNGSIDIVIKNVTFYEEK
                     "
     gene            66385..66714
                     /locus_tag="KR231_000635"
     CDS             66385..66714
                     /locus_tag="KR231_000635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112745.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0003046.1"
                     /translation="MKIFLLTILLIIICILANYVKNRIYKKSINNLKYKYSVGEKIIY
                     HQINCYYNRMVGCEILEKCYSTKFRKRNTPLYKVKAYVGDNDTTWVIPEWRIECLATT
                     YGEFPKY"
     gene            66751..67122
                     /locus_tag="KR231_000636"
     CDS             66751..67122
                     /locus_tag="KR231_000636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0003047.1"
                     /translation="MFNIYKVKIKTKRTLEQVRNQSVDFEYSEKGLKNTLKYYNLIDD
                     LKVIVVKFGDEYCLANYNEEDRKIIMEAHYLLEQDEYTGCYINEYERFKKDWENGNCD
                     GEACMVFSDDEIEIIEKLREG"
     gene            67125..67307
                     /locus_tag="KR231_000637"
     CDS             67125..67307
                     /locus_tag="KR231_000637"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0003048.1"
                     /translation="MNKRIKMKKRLIHKKCDERCVNYDFVISNNLITCNVCIGCKYKE
                     NMDKVCEENYKKLRSK"
     gene            67387..67728
                     /locus_tag="KR231_000638"
     CDS             67387..67728
                     /locus_tag="KR231_000638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015994381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor-like protein"
                     /protein_id="HBH0003049.1"
                     /translation="MANIYCENYNCKNYFEDMCMLERIEINNFKECESYLEGKNELYE
                     LENGYTIHPKDLKMVKSKDYSVEVTHIPTGITVKCRSTNSILKNKNKCLEALEEELTK
                     INSHLELEDLR"
     gene            67854..68261
                     /locus_tag="KR231_000639"
     CDS             67854..68261
                     /locus_tag="KR231_000639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RusA family crossover junction
                     endodeoxyribonuclease"
                     /protein_id="HBH0003050.1"
                     /translation="MKVFLVIDGEPVGKERPRFNLATKRTYTPQKTKDYEELIKWLYQ
                     SKVRHYFTGYIKMTLRCYYSIAKSNSKKIKEQKRNNVLRPNKKPDIDNVVKIIADSLN
                     EIAYKDDTQIVEVVASKYYSDKPRVEVILEDVI"
     gene            68363..69211
                     /locus_tag="KR231_000640"
     CDS             68363..69211
                     /locus_tag="KR231_000640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015994384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ORF6C domain-containing protein"
                     /protein_id="HBH0003051.1"
                     /translation="MNENINKEITVLGTLEIEGMKFHNIEGGFGEHKKAMLVKDIAEI
                     HNRESRQINELINKNRKRFKDGKDILDLLGVGLDDTKIKELGFTQQSINSYRGLKNKG
                     LLSGIYILSERGYAKLLKILEDDIAWELYEKLVDGYFSMRKELNNPLLSASKELQAIF
                     MLDKKQEVLETKIENVNEKLENFMDDAPLFNIECECIVKEVKRVATKSLGGHGSKAYK
                     NKSLRGKVYSDIYHQIKREFGVDSYKAIKRCQLDKVLEIVNSYKLPIVFEEEIRLLNS
                     QLSIVS"
     gene            69354..69842
                     /locus_tag="KR231_000641"
     CDS             69354..69842
                     /locus_tag="KR231_000641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0003052.1"
                     /translation="MDNNINKKELFKKVEGRLHHYKFLSAEIKNLELDIESRENEIFG
                     CKAIGYGEKVSPTYAFNSTVENEIIKKERDIARLKKLKKDKEIEKKKIENALTCLDIR
                     EEHFFKLFYNSRMKNSMVYISLEMNSDRKTCRCVRERLVYKVMDMLYPRIKENELPLF
                     KN"
     gene            70424..71101
                     /locus_tag="KR231_000642"
     CDS             70424..71101
                     /locus_tag="KR231_000642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015994390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Bro-N domain-containing protein"
                     /protein_id="HBH0003053.1"
                     /translation="MLKILQEKNVKVMWSKNGEEVWFNANDVGEELGIVNIRDTLRNI
                     DREYKKKFNESTVGDSYTRNFKDKLPNFGTTFVTEEAVYNMSFRSNKPEAKLFTKWVT
                     KTLKQIRIHGYYIATEKDQEWLDIRTEGKKVRKDFTDEIQEFVYYATSQGSNKPQMYY
                     KHFTELVRKKLGIPKGVKRDELNQSELFDIQALERIISMKLPKLIDKDMNYKEVYKKI
                     KELIEMI"
     gene            71164..71847
                     /locus_tag="KR231_000643"
     CDS             71164..71847
                     /locus_tag="KR231_000643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0003054.1"
                     /translation="MQDVKEKVKQDYIKGMKQKEISAKYDISLNTLKSWIKRYNWASE
                     KKKGAPKNKRGAPIGNKNATGPPGNKNAEKFGFFSKYLPEETRELIQEISIKDKFDIL
                     WEQITIQYAAIIRAQKIMYVKDKEEMIKELKKHESTENGEKIEYEFQFAWDRQASFLN
                     AQSRAMSELRSLIKQYDEMIHKDWNLATEEQKTRVEKLKCEVDNLSKDDIGDDELKIS
                     VDYGDRNDS"
BASE COUNT        29412 a         7485 c        12745 g        22235 t
ORIGIN      
        1 gatatatatg tagtttttag agtgctaact ctaaaaaatt agttttacta atttataaaa
       61 atttaatgcg ggtgtagctc aatggtagag ttctggcctt ccaagccagc tgtgagggtt
      121 cgatcccctt cacccgctcc aaaagattat gtggttacaa tagcagagag gatacacctg
      181 ttcccattcc gaacacagaa gttaagctct ctagcgctga tggtacttgg tgggaaactg
      241 cctgggagag taggacgtag ccacgtaatc tttttttgtt gtattaaatt taataaacct
      301 acaattgtta tatgttttta tttgtctttt atagattttt ttggcaataa atgatatagt
      361 gaagataatt aaatatattc aatatattta atttttttat tttttgtttt tataattttt
      421 ttagaagttt attttttatg tacttattta taattttggg taaaaacact ttgatataat
      481 ttcaaaaatt aaaaggttaa aaaacaaagt agaaatttat gttaaataag gagattaata
      541 tgagaagaaa tacaaaatta ttaacaacag ggattctttc aatggcaatc gtcgcaccta
      601 caatggcatt tgctactgaa tctaatgcta tggaaaataa cgctgattta aatataaact
      661 tagagaaaaa aagtatcgtt ttaggtagta cctcaaaagt cagtgttaag tttaaagaaa
      721 aaccagatgc agatagcatt acattaaagt ataaatgcta tgatatgcca ttggatacaa
      781 ctttaaacta caatcaatca actgagtcat atgaaggaac tatcaattat aataaagacc
      841 cagaatatct aaatgtttgg gaactacaag ggataacaat aaacagcaaa aataatccta
      901 aaactttaaa caaacaagaa ctagaaaaga tgggattaaa tttaaaagac tataatgtaa
      961 cacaggaatg tataattgaa gatataactt ctagaaaaga tgtaaataaa tatttaagaa
     1021 aaacttctgc acctattaca gaacttacag gaagtgatag atacgaaaca gcagttaaaa
     1081 taagtaaaga aggctggaaa aatggttcag ataaggtagt tataataaat ggggatgtaa
     1141 gtatagatgg cattatatca actccactag caactacata taatgcgcca atacttttgg
     1201 ttgaaaaaaa caatgtacct aatagtgtaa aatcagaatt aaagcgttta aatcctaggg
     1261 atgtaattat aattggagat gagaatgcta tttctaaaac tactgctaat caaattaaat
     1321 cgactgtaaa tgctagtcaa acacgtctaa agggctctaa tagatatgag acatctttat
     1381 tgatagcaaa ggaaatagat aaaaatcatg atgtggaaaa agtgtacata acaaatgcta
     1441 atggcggaga agtggatgca cttactatag cagcaaaagc aggtcaagac aagcaaccaa
     1501 ttatattaac tgataaaaat agtattacag acaacacata taaatggtta aagagtgagg
     1561 atttacaaaa tgcttatttt ataggtggcc ctcaaatgat atcaacaaat gttataaata
     1621 aggtaaatga tataactaaa gataatgtta ctaataatag agtatatgga gcagatagac
     1681 acgaaacaaa tgcaaacgta ataaaaaaat tctatacaga tgatgagcta gaggctgttt
     1741 tagtagctaa atcagatgta cttgttgatg ctttagcagc aggtccattg gctgccaact
     1801 taaaatctcc aatacttata acaccaaaga cgtatgtatc tgcataccat aaagaaaact
     1861 tagaagctaa atcggctaat aaggtatata aaataggagg aggattgact tctaaggtaa
     1921 tgaactctat agcatcatca ttatctaaac acaatacgac tccaacagaa ccaggaaata
     1981 gtgggggtaa gacagttatg attgacccag gacatggtgg ttcggacact ggaacaacag
     2041 gtaaaccatt agggggtatt aaagaaaaag actatacatt aaatacttca cttgcgacaa
     2101 ctgaatattt acgttcaaag ggattcaatg taataatgac aagagataca gataagactt
     2161 tatctcttgg aaatagaact gctttatcta actctttgag accagattta tttacgagta
     2221 tacactataa tgcatctgat acaactggga atggtgtaga agtattttat aagcttaaag
     2281 ataaagatgg aggaactact aagactgtag ctacaaatat attaaataga atcttagaga
     2341 aatttaatct aaaaaataga ggtgcaaaaa caagaacact atcaactgac cctacaaaag
     2401 attatttata tgttttaaga aataatgata tgccagctgt acttgtagaa tgtgcatttt
     2461 tggataatga gaaagatatg agtttactta atacatcaaa taaagtaaaa gaaatgggta
     2521 cacaaatagg taaaggcata gaagattcat taaaatagtc tacaatgaga gcatagaaaa
     2581 atttaaaata aattaatcta taattttaaa tttaaactaa agctataaga taagaatgta
     2641 attataatag taataaagac tgtatataca ttgtgcatat aaatgcgaaa tgaggtatat
     2701 acagtctttt tataattaat tgtaaaatga tttatgttat atgaaaaatt tacatatatt
     2761 aaggctacag ttaattgtca agagctggag tattcatttg taatacacaa tataagctta
     2821 attactatat tttattgtgt gttttttgtg gatttttatg tcaataaatg atatagtata
     2881 gataattaaa tgtattaaat atatttaatt tttttatttt ttgagtttta taagtttatt
     2941 tttatatatt acttatatat tacttatata ttatttatat tttgggttag atacactttg
     3001 acatattttc aaaagttaaa agattaaaaa taaagtagaa atttatgtta agtaaggaga
     3061 ttaatatgag aagaaataca aaattattaa caacagggat tctttcaatg gcaatcgtcg
     3121 cacctacaat ggcatttgct actgaatcta atgctatgga aaataacgct gatttaaata
     3181 taaacttaga gaaaaaaagt atcgttttag gtagcaaatc aaaagttagt gtcaaattta
     3241 aagaaaaacc agatgcagat agcattacat taaagtataa atgctatgac atgccattgg
     3301 atacaactct aaattacaat caatcaactg gggcatatga aggaactatc aattataacc
     3361 aagacccaga atatctaaat gtttgggaac tacaagggat aacaataaac agcaaaaata
     3421 atcctaaaac tttaaacaga caagacctag aaaagctggg attaaattta aaagactata
     3481 atgtaacaca ggaatgtata attgaagaca taacttctag aaaagatgta aataaatatt
     3541 tgagaaaaac ttcttcacct attacagaac ttacaggaag tgatagatat gaaacagcag
     3601 ttaaaataag taaagagggt tggaaaaatg gttcagataa agtagttata ataaatgggg
     3661 atgtaagtat agatggcatt atatcaactc cactggcaac cacatataat gctccaatac
     3721 ttttggttga aaaaaacaat gtgcctaata gtgtaaaatc agaattaaag cgcctaaacc
     3781 ctaaagatat aattataatt ggagatgaga atgctatttc taaaactact gctaatcaaa
     3841 ttaaatcaac tgtaaatgct agtcaaacac gtttaaatgg ttctaataga tatgagacat
     3901 ctttattgat agcaaaggaa atagataaaa atcatgatgt ggaaaaaata tacataacaa
     3961 atgctaatgg cggagaagtg gatgcactta ctatagcagc aaaagcaggt caagacaagc
     4021 aaccaattat attaactgat aaagatagta ttacagacaa tacatataaa tggttaaaga
     4081 gtgaggattt acaaaatgct tattttatag gtggtcctca aatgatatca acaaatgtta
     4141 taaataaggt aaatggaata actaaggata gtgttactaa taatagagta tacggagcag
     4201 atagacacga aacaaatgca aacgtaataa aaaaattcta tacagatgat gagttagagg
     4261 ctgttttagt agctaaatca gatgtacttg ttgatgcttt agcagcaggt ccattggctg
     4321 cgaacttaaa atctccaata cttataacac caaagacgta tgtatctgca taccataaag
     4381 ataatttaga agctaaatca gctaataaag tatacaaaat aggaggagga ttgacttcta
     4441 aggtaatgag ctctatagca tcatcattat ctaaacacaa tacgactcca acagaaccag
     4501 gaaatagtgg gggcaagaca gttatgattg acccagggca tggtggttca gcacctggaa
     4561 attcatctgg aggaatgatt gaaaaagatt acaatttaaa tacttcactt gcaacaactg
     4621 aatatttacg ttcaaaggga ttcaatgtaa taatgacaag agacacagat aagactttat
     4681 ctcttggaaa tagaactgct ctatctaatt cattgaaacc agatttattt acaagtatac
     4741 attataatgg ctcaactaat aaacaaggtc atggtgtaga agtattttat aagcttaaag
     4801 ataaaaatgg agggactact aaaactgtag ctaccaatat attaaataga attttagaga
     4861 aatttaaact tacaaataga ggtataaaaa caagagtact tcctagtgat tctacaaaag
     4921 attatttata cgttttaaga agtaatgata tgccagctgt acttgtagaa tgtgcatttt
     4981 tggataatga aaatgatatg agtttaataa actcatctgc aaaagtaaaa gaaatgggta
     5041 cacaaatagg taaaggaata gaagattcat taaaataaat ggaaataaaa atatttaaaa
     5101 acttaatgta aatttatagt tgtaaattta tactaaagtc aaaaaatgaa atataagtgt
     5161 atcaatagta agactgtatg tacatttgca catgtgaatg caagtatata tacagtcttt
     5221 ttttgtagtt aaatgcaata atttgattgt gttttgtaaa atacacaata tgatataatt
     5281 agataatata cacttaattt aattgaggaa ggtgattata tggaatattt atttgaaaaa
     5341 agtagtttaa aagaatatgg aaatgaagct ttagataaat atagagaatt attagataaa
     5401 actggtaata attcaaggtg tattcttttg ttagtaccaa acaataacac aaagatacga
     5461 tatgaaaggg ctctaagatt aaattatagt gaagaactga aagtaacaac atatataagt
     5521 tttgtgaaga aagaattagt taaatactgg ccactaataa tagaaaaatg tgatggaata
     5581 agtacaaagg ttgtatctcc aacatttata tcaaatagtt taagtgaata tttaatagtg
     5641 caaaaagtta aggaaaaaag gatacaagaa ggatattttg aagatattac aggaaccaat
     5701 aaatccatag caaatagtat aatgactaac ataaataagt ctgcatttaa tttaattgat
     5761 tttgatttta ttggagaaaa aatatattca tcaaagaaaa ataaagatag tatatataga
     5821 ttttcataca ctcaaatgga tgaaattata tcatattata taaattcctt actatcaaat
     5881 tcaattttag ataatgcatt aagcatatat ttatacaatc aatacctact taatgatgat
     5941 ttttatttaa aaaacttatt tacagaagtg agatatataa ttgtggatag ccttgaaagc
     6001 tcaagtaatg cagaagttga ttttataaca gaagcattgg ataatacatt acaaagttat
     6061 atatattttg attatagtag ggattattct gtatttaata atgtggatat agactatata
     6121 aatgagaaaa taatatcaaa aattaagcct aaagaagaaa atattaaaaa gaaggagatt
     6181 agaatagaag atttatactt attacctgca aatatagaat taaatcaatc aagtcaatta
     6241 tataatgaaa tgttagattt aataagtgaa aaagttatat ctcttataga agaagatgta
     6301 tctccaagag atatagcaat tatatctcct ataaacaata gtatattgga gcatcaaatt
     6361 agagattctt tgatagaaaa aaatatagat gtttttagta ctaagaagga taaaaaagct
     6421 gtggattatc catatgggaa tgcattggta gtggctacat gtatattcta tggatattta
     6481 gattttataa aagatgatga atacttaagc tttttagaaa ctcttttaga aataaatagg
     6541 ataaaagcat ttaagatttt taatgaaaca agacatttaa gtattgataa tatagatgaa
     6601 catagtcagt atcgtgatat tttacagtat attgaagaaa aaaagaagag tgatataaaa
     6661 atacatgaat ttttaactca attttacata gataaaatgt taaatttaaa agaaggtaaa
     6721 aagaatgttg ggttatgtaa aaagataata gctgaaagtg agtcttttag tgaaagttta
     6781 agtctacttg ggatgaaaaa agaaaagata tttgtagaag ctttaaaaag tacaataaac
     6841 gattattact ctgttgtcga tatagaagag ttgaaatcca aagacaaaat agtaataact
     6901 actccttatt catatatatc atcaaatata gatagaagta tacaaatatg ggtagatata
     6961 ggaagtaatg cttggaatat gaaaatagaa aaagatataa gtaatttaat tgtacttaga
     7021 aaatcttttg aagaaaaaaa gatttataca aatgaaatgg aagaatatta taaaaaatat
     7081 tatctataca atacagtata taatttgtta ttaaatgcaa agaaaatcta tgcatttaaa
     7141 agtgaatatg cgattaatgg ttatatccaa gagagtatat tatatagtat acttttaaaa
     7201 atctcacata aaggagataa aaattatgat taatataaat tatagagaag accagatacc
     7261 aataataaat tacgataatg gtactatggc agtaccagca gtaccaggtg ctggaaaaac
     7321 atttataata acaaatttag tagctaaact attacttgaa cagaaacata agagtggtaa
     7381 aatattaatt cttacatata tgaatagtgc tgtaaataat tttaaaggta gaataagaaa
     7441 gattcttgaa gagaataaaa tagatgatac taattcgtat gaagtaatga ctatacacag
     7501 tttggctgta aaaataataa aggaaaagcc agaagttgta atgttaagtg aggattttaa
     7561 catagctgac gatttgcaaa aaagtattat attaaatgaa tgtataagta gatttagatt
     7621 tgaaggtgga gaaagagctt ttagatggtt tttaaaggag caaaaagatg aacgctggaa
     7681 agaaataact cttgaagcct gggaaagagg tttttttgaa tttgcaggaa atgcaataag
     7741 tgaacttaag tataagggaa tttctccaga taaacttgaa gaaatattgt caagaggaca
     7801 caaaggaatg cttaaaatta ttttaccaat atataaattg tatgatagaa aattaaagca
     7861 aaatggattg ctagattatg atgatatatt aattttagca gaaaaaactt taagcttaga
     7921 cgaagggctt agaaagaagt ttcaaactag atacaaatat atatttgaag atgagtgtca
     7981 ggactcaaat gaaattcaag gtaatataat aaaaattata tctagcgaaa ataaaaacct
     8041 agttagagtt ggagatataa atcagagtat aacaggaaca ttttcatcat cagaccctaa
     8101 attttttaaa gaatttataa atagtgcaga tttctgttat aggatggata tgtcaaatcg
     8161 aagttcaaaa gatatacttg atttagcaaa cactcttgtc aagtatgtta caaaggaatt
     8221 tagacaagaa gaatgtagac atgctcttga agatatgcaa ataaaaactg tgccaaatgg
     8281 aatgggatat aaagaaaacc ctaatccaga acattataat ataaatgtaa agtggtatga
     8341 gagttggaaa attgaaatag agcaaactgc tagatacgtt aagggtataa aaaataaata
     8401 tccagataaa agtataggta tattggttcc atttaatgaa caagtgacac aagttgctaa
     8461 agaacttaga gagaataatc taacctttga agaattagga ccaaattctt tgaataaaag
     8521 gaaggttata aacaacatag catatattat tgattttatg ttacattgtg atgatgtaga
     8581 aaagttaata gttgtactta ataaagtttt tatagatact gataatgaag aagaaataaa
     8641 gtatttttta gaagaattaa aaaactattc taccgaagaa attatttata attttgaatt
     8701 tagtaagtta gataatgatt taatagaatt taaagaagaa agtgatatat acttaagttt
     8761 taaaagagga atagatatta taaaacagat attagaatat ccaataataa ggttagacct
     8821 cttagttttg tttattggga aaaaacttag tttagaaaaa gaagataaag ctgtactgga
     8881 ttatatatct ttttatataa agtatctagt atcagaaaat ataaatatgg atttagaaga
     8941 tgtatataat ttattgtttg atgtaaagaa cagggtgttt aatcatataa tagatgtggt
     9001 atatgagata aatggatatg aaccagagcc tggtagtata acactatgta actatcataa
     9061 atcaaagggg atggaatggg attgtgtgtt tttactaggt cttgttgaat ataatttccc
     9121 tgacaatatt aatcaaaagt ttcagagtga taaatggtat ctaaaagaaa aatataaaaa
     9181 ccctatggca attattaaat cagaagttga agctatatta aaaggaagta tttcaacaga
     9241 ttatgctcat aaaacgaaga ttgattctat aaatgaaaag attagacttt tatatgtagg
     9301 gattactaga gcaaaggaaa tgttagtact ttcaggaagt gcttatagag atgaaagtga
     9361 tatagggaat aagagaaaag agcaaaaacc atgtatatat ttaagcagac ttaatcaaca
     9421 tattattgaa aaaaggtcaa attaatatat aataagttat taaaagattg tttgaaatat
     9481 atctaaaaga ggataaaaca atatgtacag taagtaacta ctaaaaaata aagttaagag
     9541 agaagtgata tgagtgaacg ataaattaaa atatttttct tatagtcaaa attcaattaa
     9601 cacatataaa tcatgtccat tgaaatttaa atataaatat attgatagaa taaattggaa
     9661 aaatgatgat gttggtagta gagagtatta tgaaacttta aaaacaggaa gagattttca
     9721 tttgatttgt gaaagatatt ttagcaatat acctcttgga atctatttta atgaggatga
     9781 taaaaatagt aaaaagtttt taaagtggat ggaaaatata aaaaaagttg ttcctattga
     9841 aaaaggaaaa acgtatttgc cagaatatga agtaaggatg acattaaatg gggatataat
     9901 acaggcaaag tatgatttag ttgtaattgg aaataacaat atagaaatat gggattggaa
     9961 aaccgagtct aaaaagattg actataaaca cgtagaaaat agaatacaaa ctattgttta
    10021 tatgttttta gcaaaagaag taatacctaa agttttaaaa atggacataa atgttaaaga
    10081 tataaatatg agatattatc aacctgaatt tgatgactta ccaattacca ttttatatga
    10141 tgaagaaaaa catgaagcaa atagaaataa aattcaaaat tatataagta tgataaaaaa
    10201 cactaattat gaagaacata catacgaaga caatctatac aatgatatag aaaaggtata
    10261 taataaagaa gaacgtatgt gctatagaaa taaaaagcat tgcaagtatt gtgaatttaa
    10321 taagttatgt aatggcaaag aaatagatta tagtattttg gaggcggaaa tttatgggac
    10381 ttaggtttgt attaggtaga agtggaagtg gaaaatccac ctatatacta gatgagatta
    10441 aaaaagaagc tcaaaaaaat gaaacgacat caattatact tttagttcca gaacagtaca
    10501 catttgaggc tgaaaataga gtaagtaaac tatttttagg aaaagaaaaa gataagtatc
    10561 taagagttag ggtacttagc tttaagacac taagtaatat agttttttca caagtaggag
    10621 gattgacaga tgtaaatata aattctagtg gaaaagcaat gatggtatat agagctattg
    10681 aagatgtaag tgaagaatta aatgtatttt caaaatcaaa atcgcagtct ggttttgtaa
    10741 gctcaattac agatatgata tcagaaatga aacaatacaa tataagccct gaaatgttag
    10801 aaaatatatc tggagaattg gataatgaaa ctttaagttt aaaattaaaa gatataagta
    10861 aaatatataa ttcttttgaa gggaaattgc atgaaaatta tgtagatgct caagatatgt
    10921 taacttcatt ggcaagtaaa attgaattaa gcagttattt agatggagct tgtgtttata
    10981 tagatgaatt tacaggtttt acaccaaatc agtacaatgt cataaagagt atattaaata
    11041 agtctaaaag tgttaatatc tctttgactg tagatgatat caactatatt gggtacagta
    11101 aatctgatat gttttccaga acgaaattta cttattcaaa attgactcaa ttgtgcaacg
    11161 aagaaggcat aaaaatattg ccacaagtaa atttaaacac aggtgttata aaaagatttg
    11221 aaaaagttaa ggaattacag cacttagaaa gattttataa tgcttatcca tataaaatat
    11281 attcaaatca aactgaaaat ataaagataa aagagtttaa caatttatat tcagaggtgg
    11341 aagagatagc cagagaaatt gtacatttag ttagagataa gaatgtcaga tatagagata
    11401 taaccattgc tacaagagat ttaaatagat atgatttttt agtacactct atatttaatg
    11461 aatataatat accaaacttt atagataaga agagagaggc aaaaagtaat ccaatagtta
    11521 ttttaattat ttcagcttta gaaatgaaga atagacgata tgggtatgaa actatgttta
    11581 ggtatttaaa aagtggactt ataggaattg ataatgatga tataaattta ctagaaaatt
    11641 atgtgttggc taatgggatt aaaggtaaaa aatggtttga tgaaaaatgg gattatagaa
    11701 taacccaaag tctttcaggt caagaaagtg aatttgaact ggaattaaaa gagaaaataa
    11761 atgaaataaa aaatagagta ttagagccta tagtaatttt acaagaaaaa ttaagaggaa
    11821 aaaatagagt aaaagaaatc tgtagatata tatatgaatt tttattagat ataaatatgc
    11881 cagaaactat agaaagttta ataataaatt ttaaggataa aggggaactt gatgttgcaa
    11941 atcaatactc acaagtttgg gacatagtag tggacatatt agaccaaatg gtggaactta
    12001 tgggtgatga aataatttct ttagaaaaat ttataaaatt aataacctta ggttttgatg
    12061 aatatgaatt aggactggtt cctcctagta tagaccaggt acttgtaagt agtgtggata
    12121 gaatgaaaaa tccagacacg aaatatttat acctagttgg aactactgat ggtgtgtttc
    12181 cgctgattac aaaggatagt ggaatattga gtgataatga tagggaaagt cttggaaaca
    12241 aaggaatcga agttgatatt gatagtaaga ctaggagttt tgaagaacag tttcttgtat
    12301 ataaagctct tacttcgaca tctaagaatt taaccataac atatccaata tcagaccatg
    12361 aaggtaaaac gcttagacca tcaataatta tatcaagact taagaagata tttccaaata
    12421 tagaaaataa aagttattta gtggaagaaa ataaaagcac tgataaagat atacttaaaa
    12481 aaataacggt taaatcccct acatttaatg aacttataaa cgtaataaaa aattatgaca
    12541 gtgatggtta caatacagaa gagattaata gtatttggtt agatatatat aggtactatt
    12601 taaaagatga aatctacagt tctataacaa aaaaagttat aaaaggtctt agttatacta
    12661 atcaagttca taagattgaa gagaaaaaaa taaggtcatt gtataaaagt aattctctta
    12721 gcatatctag gcttgaaaaa tatgctgaat gtccatttgc ttattttata caatatggtc
    12781 taaaagcaaa aaagcgtaaa gagtattcat ttacaccacc agatttagga acttttattc
    12841 ataatatttt agataggttt tcaaaagaac ttttacaaga taatttaact tggagagata
    12901 ttgatgaaaa atatatagaa ttaaagatag gtataatagt tgatgaaata attttaaaga
    12961 taccaggata tatattaaat agttctgaga ggtataaata ccttgcatat agattaaaga
    13021 atatgttgac aactgctata actataatta gtcagcaaat aaaacaaggt tcatttgaac
    13081 caatagatta tgaagttaaa tttggcaaca atggaaaata tccacctata aaaatggtgt
    13141 tagaaaatgg acaagaagta agtttaattg gacaaataga tagagttgat gaatttgaag
    13201 aaggagaaaa taaatatata agaataatag attataagtc aggcaataag tccataagtc
    13261 taacagaaat atattatggt ctacaattac aattacttgt gtatttagat gcaatccttg
    13321 aaagtgcaaa ggatgaagat ataaatataa atccagctgc aatactatat tgtagaataa
    13381 ataatccaat agcaaaattt aatgaagata aagatgatga agaaatacaa gaagcaatat
    13441 taaaagaact tagaatgaag gggcttgtag taaaagactc tcacatagtt aaagagatgg
    13501 ataaatcatt aatagatgga gaaaggaaaa actctttagt aataccagta ggtcttacta
    13561 aggatggaaa tgtaggtaaa agtacttcag caataagcta tgaggatttc aaactgctta
    13621 gaaaatatgt aaggcatgct ataaaggatt tatgtgaaga aatgttaagt ggagaaatac
    13681 gtatagctcc atataaacat aaagatggaa catcatgtga cttttgtgat tactctgcta
    13741 tatgtcagtt tgattcaact ataaaagata acaagtataa aaatttaaat aataagagta
    13801 atgaagagat aataaaaatg atgaaaggag atgttaatta gtgagttctc ctaaatggac
    13861 aaaagagcaa ttagaagtta tagaaagtag agaatgcaat ttattggttg ctgctgctgc
    13921 tggttcagga aaaacagccg ttctagttga gcgtataatt caaatgataa caagtagaga
    13981 aaatccaatt gatatagata agttattagt tgttacattt actaatgctg ctgcgtcaga
    14041 aatgagagag aggatagggg atgctatagg aaaagcctta gatgaaaacc cagaaaataa
    14101 acatttacaa aaccaacttg ttttattaaa taaatctagt attacaacaa tacactcatt
    14161 ctgtttggat gttataaaat caaactttca tagaataaac ttagacccta atttcagaat
    14221 aggagaccaa actgaatgtg ctattttgaa acaagaagca atagaggaag tatttgaaga
    14281 tttatatgaa gaaagagatg aggggttttt aaatttagtt gaaagttatg cagaaagagg
    14341 aggagataaa gaagtacaag atattatctt gggaatatat tcatttgcaa tggcttctcc
    14401 tgaacctaaa aaatggttga ttgactcagc agaacgattt aatattgatg aaaattttga
    14461 tttttcacag tctatttggg ctagagctat attagatact gtaaaaatag agattaatgg
    14521 tctttgtcta aatatggaaa gggcattaaa agaagtggaa tcaatagaag aattagaaac
    14581 ttttgcagaa aagttatccg ttgaatataa aaaaattgct gacatttcac aagcatgtaa
    14641 taaatcttgg gatgaggcat ataaaaagat ggcaagtatg tcctttgaaa attatgtaaa
    14701 aggagtaaaa agaatttcaa aagatgctcc ttcgtatata aaagaatcaa aagaaaaggc
    14761 aaaaactata agagataaga ctaagaagtc tttagaaagt atagtaagtg ctacattcaa
    14821 taaagataat gattctatta gagaagaaat aaaatatctt tataacatag ttaaaccaat
    14881 atctagtgtt gtactgagat ttgaagagga atatagcaat aagaaaagag aaaaaggaat
    14941 aatagatttt aacgatatag agcattttgc attaaatata cttacagatg tagatgaaaa
    15001 aggtaatatt gtaccttctg atatagcagt tggatataga aacaagtttt atgaaatatt
    15061 tatagatgaa tatcaggata gtaatctagt gcaggaagta ctgcttaaag ctgttgcaaa
    15121 tacagaaact ccaaatagat ttatggttgg tgatgtaaaa cagagtatat atagatttag
    15181 acaagcaaag ccagaattat ttttgcaaaa atataataac tataatgata aaaagggaag
    15241 ctcccataga aaaataatgc tttacaaaaa ctttagaagt agagaagaag ttgtagatgc
    15301 tgtaaattat atatttgaaa atataatgaa tgagaatata ggagaaattg aatatacaga
    15361 aaaagaaaga ctaaatttag gtgcaaattt taatgtggat acagacgaga aatctattat
    15421 tggtggagca acggagatac acctaataca aaaagataat aaacttgatg atgatattat
    15481 aaatgataaa gacgatagaa ttaataacaa agaaaatgaa atagaggaag aagaaaaatt
    15541 agataatata caacttgagg ctagaatggt tggaaacatt atcaaagatt taatgaaagt
    15601 caatgaagat ggaaaaattc aaaaggtcta tgataaggga atagatggat atagacctgt
    15661 ggaatttaga gatatagtta ttcttttaag agctacatct gcatgggctc cagtgtttgc
    15721 agatgaattg atgaatatgg atataccaac gtatgctgat gttggagtgg ggtattttga
    15781 tacgattgaa ataaaaacaa tattgtcatt acttcaaata atagataatc caatgcaaga
    15841 tatacctctt atatctgtat taaaatcacc tatatttgga tttacaccag aggatttgat
    15901 tgatattaga gttcagagta aagataaaat tttttatgag gttttaaaaa gtacagcaga
    15961 gtatgatgga tttacagatt ctcaaaatga aaatgagtct gagtttatac caagtgaaga
    16021 atgcataaac aaaagtaaag attttttaat taagctaaag gaatttaaag aaaagtcaat
    16081 gtacatgagt acagatgaat ttatatggta cttgtacaca aggactggat actatgccta
    16141 tgttggagca ttgccaggtg gaagtcaaag acaagctaat ttaaaagtat tgtttgagag
    16201 agcaaaacaa tttgaagaaa ccagtcttaa aggaatattc aactttgtaa attttataga
    16261 gaaattaaaa aaatctagtt ctgatatggg aagtgcaaaa acacttggtg agaatgcaaa
    16321 tgttgttaga ataatgagta ttcataaaag taaaggtcta gaatttccag tagtcatatg
    16381 ctctgcaatg ggtaaaaatt tcaatactca agattttaaa aagagtattt tatatcatca
    16441 taatttaggg tatggacctc aatttgtaga ctatgagaga aggatttctt ttccaagtat
    16501 agccaaagaa gcattaaaaa gcaaaataaa tatagaaaat ttatcagaag agatgagagt
    16561 tttatatgtt gcatttacaa gagctaaaga aaaattgatt ataactggtt ctactagaaa
    16621 tatacaagat agtataaaga gatggtcaaa tggaattgaa agtttagata caatatcaca
    16681 atacgagata ttaaaaggta aaaatttttt agattggata atgccttgtg tattaagaca
    16741 tagggattta tctaatctac tagaagaagt aggattagac gcagttttta atgttgaaca
    16801 taattcaaaa tggtatggaa agttgtggaa taagagtgat attttagtgg aaaagaagag
    16861 tgatgaagaa aaagaaagta ttgaagaaat tcttgaaaaa atagatgtag ataatcctga
    16921 tagtgattat tacagtgaaa tagaagaaaa attaaactat atatatccat atgaatttag
    16981 tacaagaaaa cctgctacta tatctgttac agaaataaaa aagatacaaa ataattatga
    17041 agaagagtta ataaatacta tatttgaaca aaaagtaata ttaaaaaagc ctctatttat
    17101 tcaaaatgaa gaagaaagag aaaaaataag tggaacagaa agaggtacaa tagtccattt
    17161 agttatggag gttttagact taaaaaatgt aagtagtgta aatgatataa aatcacaaat
    17221 aagaggtttt gtttcaaaag gtataataac agaaaaacaa gctagtatag taaatccata
    17281 taaaatatat aaattttttg cctctaacat aggaaaaaga atgttgaatg ctgaaattat
    17341 aaatagagaa aaatcaattt atgcacaagt aaatatgaaa gacatatata tttatgaaaa
    17401 gcttataaac aatgacgata aaaaacttta tgataatgaa agtgtcatgt taagaggtat
    17461 agttgatgct tattttgaag aagacaatca aatagttttg gtggattata aaacagattt
    17521 tgtaaatgag gaaaatataa atcaaataat agagaaatat aaaaaacagt tggatttata
    17581 tgcagatatt attgaaactt taactggtaa gtcagtaaaa gagaaatgta tatatttatt
    17641 tggagttgat gaagctgttt gttattagtt tttatatata aattaaacct aaaagataga
    17701 ggaaggggaa aaaatgagat ttattcatac atcagattgg catctaggga agtccctaga
    17761 aggccattct agaattgagg aacaagcaaa gttttgtgag gaatttataa aaatagtaga
    17821 atcaaatgaa atagatatgg ttataattgc tggagatgta tatgatactt ctaatccacc
    17881 agcacaagca gaaaaactat tttatcagac tgtatcaaga cttgccaata atggtcagag
    17941 gtgtgtatta ataatttcag gaaatcatga taatccagag agactctctg caataacacc
    18001 tctagcacat gaacagggga tacttatata tggttatcca ttaagtgcta cgatagaagc
    18061 taagtataaa gggtttgaaa taacatatgc aactcaggga tgtacaaaac tgaatataaa
    18121 tggagaaaat attgtggttg ctacattacc ttatccaagt gaaaaaagat taaatgaagt
    18181 tttttcaagt gaagatgagt ttgagaaaca aaaaaattat tctgaaaagg taggagatat
    18241 atttagaagt ttagaagaaa attttagaag tgatactata aatatagccg tatcacatat
    18301 atttgtaata ggtggagaga gtactgaatc agaaagacct atacaattag gtggaagttt
    18361 tttagttgaa agaaaagatt tgccagaaaa ggctcaatat actgcactag gtcatttaca
    18421 taaacaacaa aaagcttccg aacgtttaaa tgcatactat tctggttctc cacttcaata
    18481 tagcaaggat gaaagagcgt ataccaaagg ggcatacata gtggatataa aagctggtga
    18541 aaaaccaata attgaagatg tatattttaa taattacaaa cctatagaag tatttaaatg
    18601 taatggaata gaagaagcac tagatatatg tgagcaaaat caagatagag agatttggtc
    18661 atattttgaa ataaatactg atgagataat atcacagaat gaaattaaaa aaatgaagga
    18721 actattaaaa gacataatag aaataaaacc aataataaca tcttgttatg aacaagaaag
    18781 tgtagatata aaagaaaagt ctatggcaga gttgtttaga gagttctatt cttttagtaa
    18841 aggtgtagag ccaaaaggag aacttatgga tttatttcta gatataataa gtgaagaagg
    18901 tgaatcagca gatgagacca attagattag aacttacagg gcttaatagc tatattgata
    18961 aacaagttat agactttgaa aaattaattg aaagaggttt gtttgggata tttggaacta
    19021 ctggaagtgg aaaatctaca atcttagatg caataactat tgctatgtat ggaaatatat
    19081 ccagaaatac aaaagaatat ataaacagtg tgtgcgataa ggcaattata tcatacgagt
    19141 ttgagatagg aagcaaaaac actagaagaa gatacattgt agatagaacc attgctagaa
    19201 gcaaaacagg aacaaagacc tctaatgcta gattaataga agtattgaat gacaataccc
    19261 aaaatgtttt agctgataaa gttgtggaag taaatgaaaa agtagcgcag gtcgtaggat
    19321 taacggcaaa tgattttact aggtcagtag ttttaccaca agacaaattt aatgagtttc
    19381 taagattatc acgtgcagat agaagagaca tgttagagag aatttttaat cttgagaaat
    19441 atggaagaag tcttggcgaa aaagtgaaaa agagaaaaaa tatacagtta caaaatttaa
    19501 aagatttgaa atcaaaatta agtcaatatg atggaattac agaggaagta tataacaata
    19561 taaaccaaga attaatagag ttaaaaaatt tggaaaaaga taagaataat gctttagacc
    19621 tagctcaaaa atcttatgaa gaaagtaaaa cagtatatga agaacaatta aagttagaaa
    19681 aaaatgaact tagaaaaaat gagcttgatt taaaaaatag tgagataaaa gaaaagattg
    19741 ctcttgtaga aaatgatagt aacgctaaaa aggtagaccc atacataagt tcagttcaaa
    19801 atctagaaaa aaagatagat gaagatagct tcgcagtaag taatttagaa aagaaattag
    19861 caatattaaa tcaggagctt gaagttacaa aaaatagata tgaaaaaata aacaaaatta
    19921 agaatgaaga aatccctaaa ttgagtgaag aaaaaataag attgcaacaa gcaataaaat
    19981 tagaagaaga gttagtttta ttagatagag agttaaaaga gctaaaagaa agtggaatta
    20041 atttaaataa gactaaagtt gaattagaaa aagtaaagca ggtgtcagag tccagaaaag
    20101 atgcagttac taaatctata aaagaagttg aaggaaagat tgataaagta aatataagtg
    20161 cagaattaaa acaaaaaata tttctagcat atgaatacga gaaagattac aacaacgtat
    20221 tggaagaaaa aaatcaaaag ctaaataaac tagaagaaat actcaaagag acagaaaata
    20281 taaatttaaa agttagatat attgataaag ataagaatga tgtaaatcgt aatttagaaa
    20341 atttatcact tcacttggat gttcttctta aaaaatgtcc tggtaagagt gctgatttac
    20401 ttttaaaatc tgaatatgtt actgaattaa gaaataaagc aaataatact aaagaaaatg
    20461 aaattaagaa aagcagtata caagatgaat taaagataat acttgaaagt aagtttaata
    20521 ctgaaaggga agtaaattta ctaaatgaaa aacttgaaaa taatagaaag aacagagatg
    20581 acttagaaaa agaattagaa gaactaaagt atttaaattt agcctctgaa cttagacgtg
    20641 aattaaaaga aaatatgcct tgtccagttt gtgggtcaaa acatcatgaa aatcatgata
    20701 taactaagta tgatgaaaat atatcttttg tcaaagaaaa actggagaaa ttagaaaaag
    20761 aaaaaataag tataagaaac aatatagagg aattaaatgc taaagtaagt gggtatttat
    20821 ctatagaaaa aatgaagact aaagaacttg aagatgtaaa aggaaaacta ggggggattc
    20881 catctagtca attattaaaa aaacttgatg aagaacaaag aaaacttgca ttgttaaaat
    20941 ctaatattca ggagtgggag aaagaaaaag agagtactga aaataaagta acattagcta
    21001 aagaagaaaa aaataaaatt gaaaaagaag aattaaaaat aagagagagt ctgaataatt
    21061 ataagaaatt aacaagagat ttaaacatag aaatagaagg tttagaaaat aaatgtaaaa
    21121 aacttaaaca ggaataccta ggattaaaga cgattactaa agtctctaat ctattgtcaa
    21181 aagtaaaaga aataagggag aatgaaaaag aattagaatt actaagtact gggcattcaa
    21241 atttattaaa aaatagagac tcactagata ttaaaataag agaaaatgag agtaaactac
    21301 atgaaataga gatagaatta ataaaggcta gagaattata tgtagaaaag aaattgagta
    21361 gagataataa gtataaagaa gttattagca taacgaaagg tgatttagct aaaaatcttt
    21421 tacataatgt tgaagaaaat atatgtaaga tattagaaca agaagaatca agtaagaaaa
    21481 aattggaaga gcaaagatta gaatatgaaa aaaacattgc tgaaaagcac aatatagatg
    21541 gtagacttaa aactgctaag gaacaatata aagaccaaaa atcaacacta aataaactat
    21601 tggcagaaaa taaatttgaa agtatatatg cagtaaaaag agctttatta gatactgatg
    21661 cagtaaaaaa attgattgaa gaaatactag agcatgaaga agaacaaaag ttattatcat
    21721 ttaaaataaa atcatcaaaa gaaaaattaa atggaagaag cataaagaag gagtactttg
    21781 aacagttaaa agatgaaatt tataatttga aagtagaaat aggaaatata tccaaagata
    21841 ttggagctaa tcaaaatcag ttaataacat taaaagactc tttagataag ataaatgatt
    21901 ttaataaaca acttaaggta gttgaacaca atgtggactt attggaagaa ttagataaat
    21961 gtgtacaagg aaataaattt gtagaatatg tttctacaaa ccaattaaaa tatatagcgt
    22021 tggaagcatc aaaacgattg gatggaataa caaaaggaag atatgcactt gaaattgact
    22081 caacactaaa ctttgtaatg agagataact ttaatggagg agaaagaaga agcattgata
    22141 ctctatctgg tggagagaca ttcttgacat ctctatcatt agcacttgct ctttcatctc
    22201 aaatacaatt aaagggaagt gcaccattag aatttttctt tttagatgaa ggttttggtt
    22261 cattagatag tgaactttta gaaattgtta tagaatcctt ggaaagattg catagtaata
    22321 atctaagtgt gggtataata agtcatgtcg aggaacttaa aaatagagtt cctgttaagc
    22381 tattagtttc atctagtgag gctggaatag gttcaaaagt aaaaattgaa tatagttaga
    22441 aaatatatgt taattgaata tattatctaa tatttccaaa taatatgtaa ttgtgatata
    22501 ataaaaacta atattaaagt tatttataat taatattaat ataaaaacat gtaagtagga
    22561 gtgtggtaag tgttggaatc gcccaataat ttgattcaga ttattttttt aatagtatta
    22621 cttatagggt ctgcattttt ctcagcatct gaaacggcct taatgtcgtt gagtaaaatc
    22681 agaatcagat atatgcaaga tgaaggagtt aaaggagcta agttagtaag ttcattaata
    22741 gaaaatccaa ataagctttt aagttctata ttggttggaa ataacgtcgt aaatatagca
    22801 gcaacatcca tatcaacatc tttgtttata ggattaatgg gagaaaaagg agtggcactt
    22861 gctacagctg ttatgacagt attagtatta atatttggtg agattactcc aaaaacaata
    22921 gcagcaaata attcagaaaa ggtttctcta ttagtatcta aacctataaa agcaattata
    22981 tttatattaa gaccaatagt atggatattt aatataatta caaatattat atttaaatta
    23041 tttggtataa caaataaagg agctaaatca ttcataactg aagaagagct aaaaactatg
    23101 gtaaatgtaa gtcatgaaga aggcgtcctt gaaatggaag agagagaaat cataaataat
    23161 gtttttgaat ttggagatat gcaagctaaa aatgcaatgg tacaaagaat agatatggta
    23221 gctatagata tggaagatag ttatgatgag ataatacagg tatttaaaac tgaaaaatta
    23281 agtagaatgc ctgtgtatga agaaactata gatgatattg taggaatact taatataaaa
    23341 gatattatat ttttatctga tgaagaaata gagtcatttg atattaaaaa ttatatgaga
    23401 gaaccttttt tcacgtatga gttcaaaaag ataacacaac ttcttgaaga gatgaaactt
    23461 gaaaaaagtc agatggctat agttgtagat gagtatggtg gaacatctgg acttttaact
    23521 atagaagatt tagtagaagt cattgttgga gatatagagg atgaatatga tgaagaagag
    23581 gatgaaatac aagttataaa agaagatgag tatattgtag atggaagtac taaaattggt
    23641 gatgttaatg aacttattgg tgtaaacttg gaatctgagg agtttgattc cataggaggt
    23701 tttataattg gacacctaag cagattgcca gaagaaaatg aagtaattga agttgataat
    23761 ataagatttt gtatagaaag tatagaaaaa aatagaatta aaaaaataag aatatataca
    23821 taatgtaata atgttcttaa atttattaga agtgtataaa tataaaagat atcttttata
    23881 tttatacact tctttttatt ttgtattcaa ataaaactag tatgaaatgg acaaaataaa
    23941 aatataaatt agaagaaagg agatttttaa gatgagcata ctagaaaata attttttata
    24001 caaattaaaa aacaacacta tctttttttg tatatataca ttgttattta tttttattta
    24061 caaagcgttt ccatacatag ctccattttt tctaggtgct ataatagcac ttatgattaa
    24121 tcctatatca caaaagttag aaaataagtt tcatataaat aaaggtatct ctactcttgt
    24181 tctaagtttt cttgcagtgg ctatagtcag tacagttact acaataatag taataaattc
    24241 aatgaaagaa ttaatgggat ttttaaataa tatatctgct aatcctgagg atataagtaa
    24301 tactattatg tattttttaa ataaaataaa tgactttatg aaatcatttc aagaaatagc
    24361 caattttgat gtagaacaat tagtaaacaa attcagtggt gaagtaatgc aaattacaaa
    24421 aaatcttctt actagtatac ttggattggc tacttctatt ccatatatta taatatttat
    24481 aattaccttg tttattgcta cgtattttat agcaaaagac cttgataaga ttgaaaatag
    24541 tttttataat atgtttactg ttgatgttag aaagaaggta aaaaacgtaa agaaagaggc
    24601 agggctttca cttgttggat atataagggc ctatacaata cttatggcta taacattttt
    24661 tgcaatctgg ggaagttttg ctttatttgg attgaaatac ggtctaatag tagggtttgt
    24721 aggagcttta atggatttaa ttccattcct aggtataata acaatatatc ttccagtaat
    24781 tgtttattat tttcttataa aaaattattt tatagctata agtatgactg tgatattttt
    24841 tgttttgtct ttgattagag aaatacttga acctaaacta gtatcagtaa atgttggact
    24901 aaatccatta gctaccctag cagcgatttt tattggaatc caagtaaaag gaataattgg
    24961 agtaattttt tgtttgggtt tggtatgtat gcatgatata cttaagaagg tggatatttt
    25021 ttaattataa taattgatag attttttaaa aataaaattt tattcacagg taaataaaaa
    25081 aatattaatc ttattaagaa agagggtata tacgtgaaac aaaaagtagt ggaaagattt
    25141 ttaaaatatg tatcatttga tacaacatct aattctcagt gtgagaactg tccatcttca
    25201 gaaggtcaaa gagttttagc taagtatata gttgaagagc taaaaacaat gggtgttgat
    25261 gatgtgagtt tagatgaaaa tagttatata atggctactt taaaaggaaa tactgatggt
    25321 gtggatacta taggattcat atcacattta gatacaattg aagatgttag tggaaaagat
    25381 attaaaccaa aaataataga aaattatgac ggaaaagaca tagttttaaa tgaagcgtta
    25441 aatgttatta cgtatgtaaa ggattctcca gagttggaag aatttaaagg tgacgattta
    25501 atagtcactg atggaacaac tctacttggg tctgatgata aagctggtat agctgagata
    25561 gtgactgcaa tagagtatct aataaatcat ccagaaatta aacatggaga tataaaaata
    25621 ggatttacac cagatgaaga aattggtaga ggtgctgatt tatttgatgt tgaaaaattt
    25681 ggagcaaaat atgcatatac tttagatgga ggaatagttg gagaacttga atgtgaaaat
    25741 tttaatgctg caaatgcaac tattactata catggtagaa atgttcatcc aggttcagct
    25801 aaaaataaaa tggtaaatgc tatacatata gctgctgaaa tatcagaaat gttcccagca
    25861 gatgaaagac cagaaacaac agaaggatat gaaggatttt ggcatttaaa ttctataggt
    25921 ggaaatgtcg agaatgtaag tatggcttat attattagag accattgtaa agaaaaattt
    25981 gaaaatagaa aatctattat gatagagaat atagaaaaaa taaataagaa atacgataat
    26041 agagtggaat tggatttaaa agactcttat tacaatatga aagaaaagat tgagccagtt
    26101 atgtttatag ttgatatagc taaagaagct atggaggaat taggtataaa accacgttta
    26161 gttcctgtaa gaggtggtac tgatggagca agattatctt ttaatggatt accttgtcca
    26221 aatatattta ctggtggatt aaacttccat gggaaaaatg agtgtatacc agttagttct
    26281 atggagaaag ctactaaact aattgtaaga atagctgaaa aatatgctga aagagtttag
    26341 ttaaaaagta tttaaaaatt aagcatttaa agttataata gctatatcat tctttataag
    26401 tcaagctgat tataagcttg tgttgtactt aaaatggtat agctattttt gtaattattt
    26461 ttataaaaga taattatttt tagtttaggg tatcaataaa aagtatgaat atcaataggt
    26521 attaacattt aaaaggggga attgtattga aaattaaatc taaaaaaata atagcatttg
    26581 cactttcact tgggattatg ttgccaagtt gtgtatatgc agacaatatt agtaaaaatc
    26641 aaaatgcaca ggtagatatg aacaattatc ttcaaggtag aaaatctcca aaggaggaaa
    26701 aacttattgg tgaagataga tttgatacag cgataaaaat atctcaaagt ggttggaata
    26761 atggttcaga aagggtgttt ctagttaact caaattcatt gccagatgca ttggcttcaa
    26821 ctcctttggc aagtaaattg gatgcaccaa tactgcttac aaataaaaat agtataccat
    26881 ataatgtaac agaggaaata aaaaggctta atccagcaga agttatttta attggaagtg
    26941 aaggagctat ttcatcaagt gtaaaagaat ctcttgaaga tatggaagta ttagtcagta
    27001 gaatcggtgg agcagataga gaagaaacat ctttacttct tactagacag ctagatgata
    27061 ctggtgattt aggtgtctca aaagtggcag tggttaatgg gtataatgga ctggcagatg
    27121 caacttcaat atcaagccca gctgcaagtg ataatacagc tataatatat acaggtaagg
    27181 atagcataag aagtgaggca aagaatttta ttacacaaaa ctcaactaag acatacatag
    27241 taggtgggga gtacagtata agtaaaaaac ttgaaggaca gttagtaaac tcagaaagac
    27301 tagcagggac agatagaaaa gatactaatg cgaaagtttt agaaaagttt tatggaaaat
    27361 caagtaaggt taataatatg tattttgcaa aagatggaag tggtagagaa gctgatttag
    27421 ttgatgggct tgctgctgga gtattagcat caaaaacaaa gtcacctgta gtacttgcaa
    27481 gtggaagttt aagtagtgca cagaaaagtt ttataaaaaa agtaaaggct gataaatttg
    27541 tacaagttgg tggaggtaaa aatagtaaac catatgcaga agcattagcc ttacagtaat
    27601 attgtgtaaa tcaaaattaa tatataataa tagcaagtaa accaagttgc actttaatat
    27661 atataataaa ataagtaaac taagttatat ttcagtataa tatataataa aataagtaaa
    27721 ctaagttata tttcagtata atatataatg aaataagtaa actaagttat atttcagtat
    27781 aatatataat gaaataagta aactaaatta tactccaata taatatataa tagaaacaag
    27841 taaactaagt tatatttcaa tatagcatat aataaaacaa gtaaaccaga ttctatttaa
    27901 ttagaagttt aaggtattgt acttaaactt ctaattgaga tagaaataaa atggtttact
    27961 tgtctttatt atgaatttaa taaattaaag cttattttat ttttattaaa aatttactaa
    28021 tcattgatat ttattatatt tccagtattg atgtcaatta agtttatatc aagttcaagc
    28081 tcatcctcat catcagtttt tatgatatct ataattgcga cagaatggct tccatctttt
    28141 gggatagaag tacttcctgg atttattact attaaattat catccatgta tagttttttt
    28201 acatgagtat gtcctaaaac taatatgtca ccacccattt tctttgcttt gtcaataatt
    28261 tcttcttctg attctatata accatgattc aatataattc taatttcacc aaattggctc
    28321 atgacataag gactctgaat aggatgttct ataaccatct ggtcaacatc tgcatcacag
    28381 ttccctttta caatcacaat gttttctaat ttatttaatg tctcaataaa ttttttagga
    28441 ttatatcctt ctggaatatc atttctaggt ccatgatata agacatctcc accatgtaat
    28501 aaaacatcac aatcagataa tacatttaac gctttttcaa agtaaagtaa gctaccatga
    28561 gtatcactca ttattcctat tttcatatta aaaatcctcc taagtacagt ctataaaaat
    28621 ttttcagata ctctatgcca aaactcatag tttgacattc taagtaattt tatttttgca
    28681 tcagatatac taacttttat attttcgatt tgtctaaatc tgtgctcaac tccatcaacg
    28741 acaatcaata cagaatcttc aaatctatat tctggtgcaa tctttataac agattcattt
    28801 gaacatatta tacttgatgt aaagcaccta tatgcattgg tatttatcgg atgtaaaggt
    28861 gtaatctgca taagttcaag atttatatca acaatactac ctccagcaga atagttatag
    28921 gctgttgaac ctgtggaagt agaaataatc ataccatctc cactaaaatt ttgtatatgt
    28981 ttattatcaa ggcttaaatt taggtgtata gtcctagact tgtctcctct tataacaacc
    29041 tcatttacag caagcatatt agaaccacta gtagttgtat atacttccgc attaagaagt
    29101 gacatttctt gaataatata atcttttttt gtataagctt caataaagct atcaatctta
    29161 tctggtaaaa tatcaggaaa aaaccccaga tgacctgtat ttattcccat tatgggaatc
    29221 tcaggaaaat cgaaatctct aactgttctt aaaaaagagc catcaccacc aattgatata
    29281 ataagctctg tgtctggata aatatctgaa tacacttcaa agccagcatt gataagtttt
    29341 ctagttaaga gttctttagt ctcaagggac ttatttaatt ggtttgtatt tatagttata
    29401 attcttttca tatattcacc tcttcatact ttgtattata acatagtttt ataattctta
    29461 atttataaat ttataaatga catttgtagt gaatgtgtta aaatatgtat aggtgggtat
    29521 aaaaaaatgc ataagaggtg aagatgtgtt tagcataagg aatatcacaa aaaaattagg
    29581 aaaattcaag ttaaataata taaacttaga gttaaaggaa ggggatattg ttgggattat
    29641 aggaccaaat ggttcgggaa aaacgacttt aataaaaatt ataatgggga ttattgatgc
    29701 agatgaaggt gaaattgaac tttgtaatga aactattgaa aattctccaa taagctttaa
    29761 aaacaatatt ggttttgtat atgattcttt acaattttat ccgcatttaa aggttaagga
    29821 atttagaaaa atagtttctt tattttataa gaattttgat agagaaaggt ttgatgaata
    29881 ccttaataag tttgatatag aagaaaatat gcatattgaa aatttatcta aaggtcaatc
    29941 tgaaaagctt atgttatcaa gtgcacttag tcacaatgct aagttattga ttttggatga
    30001 accaactgct gggatagacc caattgtaag aactgaaata atgcagtact tacaagattt
    30061 tgtgaaaaat ggaagtagta gtgtaataat ttctactcat aatactgata atttaattaa
    30121 aattgctgat tatcttgttt ttataaatag aggaaatcag atttttactg ttaagaaaga
    30181 attaatagaa caagaatata agataattag ggcaaataaa gcagagttag aagcaattaa
    30241 agaaagcata gttggtgtga aagagtataa atattataat gaggcacttg ttaaagttgg
    30301 agatagcttg aaagtaaaaa gcctattgat agaaattgat aagcataagg tcaaaaatcc
    30361 tactatagaa gaactaatgt attattatgt aaatgaggtg agatgatgtt caatttaata
    30421 agaaaagatt taataatagg gattagttca gatggtatcc gtaatttaaa gtacatattg
    30481 ctattttttg tgttttattt tttccttaat tcaatttcat attatacagt aagtattgtt
    30541 gttagttatt tgatatttat aaatacgttt gagtgtgatt atgaaaatga ttcaaggatt
    30601 tttataagga gtatgccagt tagtatagaa gatatagttt actcaaaata tttattaggt
    30661 gtaggattaa taatttctgt aacaataatt gtgtccttac taagtaaatt gacatcacta
    30721 gtgttcttta gaaatatggt tttaaatgat gtattttttt ctgtaaatat atttttagca
    30781 attttgacga ttttactgcc tttaattttt aagtttggat atggaaaaat gaaagtttgt
    30841 ggttttatag taagtatttt aatttacttt gtatatggaa gtcttttgaa gatgattagt
    30901 atgattgtat atcaagtaaa gcattttaat tatagtaaag ttggaggagt atatctttca
    30961 aattatgtaa ctgatatagc taatactaag tatataaatt tatatagtat gacattttta
    31021 acaataataa tttttataat atcaatgtat ttttctatta agatttcaaa aaagaataag
    31081 tttaattatt aaaattttga ttaatattat agcacaatag cacaaaatat aaggagacta
    31141 aaaatgaaga agtttataaa agtttcattt tttattttgg ggatttttac actattcata
    31201 gctataaata aattagtata tagagatatg gtaagtgtca aagattatga aataaatcat
    31261 ttagaggaaa ttgtttttga ttttgatagc aggagaagta gagatgttgg tactattgta
    31321 agatttaaaa taagcaataa tagtaaatat agttataaat taaacagtgc taaaatgaag
    31381 tttgaaaatt gtgtggaaaa taaaaaggga atgaataagt gttctgcata tgtaaatgta
    31441 gatttattta atgaaaaaaa ttctataact gaaagaactc tgaaatatgg aataaaacca
    31501 aataatcaag gttatgttga ttttgtaatt ccaaaaggac taaattttga ttataggtac
    31561 tttaatgaat ctggtatgag tgtagagtat aaaggagaat atattgtcaa tattccaatg
    31621 gcaaaaggac tttatctagt agttggaaaa aataatgata catggaatgc taatatcatg
    31681 gaataatttg aaaaataaat caattataga tataattaag aataatatga aatttataaa
    31741 agttcagact aggagggata tttaatgtca ataagtaatg taagagagta ttttaaacaa
    31801 tttggcaagg aagacagtat attagaattt gaacaatcta gtgctactgt ggaacttgca
    31861 gctgaagcag ctggggttat tccagcaaga atagctaaga cactctcatt taaaatagga
    31921 gatgatgcaa ttttaattgt gacagctggt gatgctaaga ttgataataa gaagtataag
    31981 gctgaattta attgtaaggc taaaatgttg acaccagaag aagtcttgga gtttactgga
    32041 catgctattg gtggagtctg tccatttggt ttaaaaaatt ctataaaagt ctatttagat
    32101 gattcaatga aaagatttga tacagtattt cctgcatgtg gcagtagtaa ctctgcaata
    32161 gaacttacat gtgaagaaat ggagaagttt tctaagtgtg aaaaatgggt agatgtttgt
    32221 aagaattggt aaaaaaatat agtaaactat agtaggaatt agtaaaaaac tacctctgta
    32281 tacaatctat acagaggtag tttttttgtg taaatattta taaatctaag aggaaaatct
    32341 aatttaaact aataatccaa aataaagtta aaaaattctg attttttttc gaaacaataa
    32401 aaaaatgaca aaaaagtgga aaaaatgtaa taaatattgt taaaaaaata attagaaatt
    32461 attgaaaaat tatcctttga gtgatactat tatagatgta agatatttaa aaataaaaaa
    32521 tagtcagata aaaatacgat tatttagctc tattaaaata atttttatac gataaaaatc
    32581 ttctgtacat ggctaaaaaa cagatgtaca gacaatattt aatgtttaat ataccctaat
    32641 ataaatatcg taaacaaatt attttatctg taaccagtgt gaaagaaatc ttattctaac
    32701 ttgaaatttc acaaaattcc aaaaagcgag atttttttta agtatagttg attttaaatt
    32761 aacaatttat gattaaatta atgtcataat tggttagtat aatcacatat aaatatagag
    32821 cgtagtttga ttaaggttat aaatttctcg acgtatattc aaatacctta ttatagatgt
    32881 tgccgagatt ttaattaata aatgaaaata aaatatttat aaaatactga ggaggctatt
    32941 atggatttaa attctaaaaa atatcagatg cttaaagagc tatatgtaag cttcgctgaa
    33001 aatgaagtta aacctttagc aacagaactt gatgaagaag aaagatttcc ttatgaaaca
    33061 gtggaaaaaa tggcaaaagc aggaatgatg ggtataccat atccaaaaga atatggtgga
    33121 gaaggtggag acactgtagg atatataatg gcagttgaag aattgtctag agtttgtggt
    33181 actacaggag ttatattatc agctcataca tctcttggct catggcctat atatcaatat
    33241 ggtaatgaag aacaaaaaca aaaattctta agaccactag caagtggaga aaaattagga
    33301 gcatttggtc ttactgagcc taatgctggt acagatgcgt ctggccaaca aacaactgct
    33361 gttttagacg gggatgaata catacttaat ggctcaaaaa tatttataac aaacgcaata
    33421 gctggtgaca tatatgtagt aatggcaatg actgataaat ctaaggggaa caaaggaata
    33481 tcagcattta tagttgaaaa aggaactcct gggtttagct ttggagttaa agaaaagaaa
    33541 atgggtataa gaggttcagc tacgagtgaa ttaatatttg aggattgcag aatacctaaa
    33601 gaaaatttac ttggaaaaga aggtcaagga tttaagatag caatgtctac tcttgatggt
    33661 ggtagaattg gtatagctgc acaagcttta ggtttagcac aaggtgctct tgatgaaact
    33721 gttaaatatg taaaagaaag agtacaattt ggtagaccat tatcaaaatt ccaaaataca
    33781 caattccaat tagctgatat ggaagttaag gtacaagcgg ctagacacct tgtatatcaa
    33841 gcagctataa ataaagactt aggaaaacct tatggagtag aagcagcaat ggcaaaatta
    33901 tttgcagctg aaacagctat ggaagttact acaaaagctg tacaacttca tggaggatat
    33961 ggatacactc gtgactatcc agtagaaaga atgatgagag atgctaagat aactgaaata
    34021 tatgaaggaa ctagtgaagt tcaaagaatg gttatttcag gaaaattatt aaaatagata
    34081 aatattaaaa tatacacaat aggtcgatat taaaatagat atggaggaag gatttatgaa
    34141 tatagtcgtt tgtataaaac aagttccaga tacaacagaa gttaaactag atcctaatac
    34201 aggtacttta attagagatg gagtaccaag tataataaac cctgatgata aagcaggttt
    34261 agaagaagct ataaaattaa aagaagaaat gggtgctcat gtaactgtta taacaatggg
    34321 acctcctcaa gcagatatgg ctttaaaaga agctttagca atgggtgcag atagaggtat
    34381 attattaaca gatagagcat ttgcaggtgc tgatacttgg gcaacttcat cagcattagc
    34441 aggagcatta aaaaatatag attttgatat tataatagct ggaagacagg cgatagatgg
    34501 agatactgca caagttggac ctcaaatagc tgaacattta aatcttccat caataacata
    34561 tgctgaagaa ataaaaactg aaggtgaata tgtattagta aaaagacaat ttgaagattg
    34621 ttgccatgac ttaaaagtta aaatgccatg ccttataaca actcttaaag atatgaacac
    34681 accaagatac atgaaagttg gaagaatata tgatgctttc gaaaatgatg tagtagaaac
    34741 atggactgta aaagatatag aagttgaccc ttctaattta ggtcttaaag gttctccaac
    34801 tagtgtattt aaatcattta caaaatcagt taaaccagct ggtacaatat acaatgaaga
    34861 tgcgaaaaca tcagctggaa ttatcataga taaattaaaa gagaagtata tcatataatt
    34921 taagggggga taaagaatgg gtaacgtttt agtagtaata gaacaaagag aaaatgtaat
    34981 tcaaactgtt tctttagaat tactaggaaa ggctacagaa atagcaaaag attatgatac
    35041 aaaagtttct gcattacttt taggtagtaa ggtagaaggt ttaatagata cattagcaca
    35101 ctatggtgca gatgaggtaa tagtagtaga tgatgaagct ttagcagtgt atacaactga
    35161 accatataca aaagcagctt atgaagcaat aaaagcagct gaccctatag ttgtattatt
    35221 tggtgcaact tcaataggta gagatttagc gcctagagtt tctgctagaa tacatacagg
    35281 tcttactgct gactgtacag gtcttgcagt agctgaagat acaaaattat tattaatgac
    35341 aagacctgcc tttggtggaa atataatggc aacaatagtt tgtaaagatt tcagacctca
    35401 aatgtctaca gttagaccag gggttatgaa gaaaaatgaa cctgatgaaa ctaaagaagc
    35461 tgtaattaac cgtttcaagg tagaatttaa tgatgctgat aaattagttc aagttgtaca
    35521 agtaataaaa gaagctaaaa aacaagttaa aatagaagat gctaagatat tagtttctgc
    35581 tggacgtgga atgggtggaa aagaaaactt agacatactt tatgaattag ctgaaattat
    35641 aggtggagaa gtttctggct ctcgtgccac tatagatgca ggttggttag ataaagcaag
    35701 acaagttggt caaactggta aaactgtaag accagacctt tatatagcat gtggtatatc
    35761 tggagcaata caacatatag ctggtatgga agatgctgag tttatagttg ctataaataa
    35821 aaatccagaa gctccaatat ttaaatatgc tgatgttggt atagttggag atgttcataa
    35881 agtgcttcca gaacttatca gtcagttaag tgttgcaaaa gaaaaaggtg aagttttagc
    35941 taactaattt cttggggagg gtattatgag tacaagtgat gttaaagttt atgagaatgt
    36001 agctgttgaa gtagatggaa atatatgtac agtgaaaatg aatagaccta aagcccttaa
    36061 tgcaataaat tcaaagactt tagaagaact ttatgaagta tttgtagata ttaataatga
    36121 tgaaactatt gatgttgtaa tattgacagg ggaaggaaag gcatttgtag ctggagcaga
    36181 tattgcatac atgaaagatt tagatgctgt agctgctaaa gattttagta tcttaggagc
    36241 aaaagctttt ggagaaatag aaaatagtaa aaaagtagtg atagctgctg taaacggatt
    36301 tgctttaggt ggaggatgtg aacttgcaat ggcatgtgat ataagaattg catctgctaa
    36361 agctaaattt ggtcagccag aagtaactct tggaataact ccaggatatg gaggaactca
    36421 aaggcttaca agattggttg gaatggcaaa agcaaaagaa ttaatcttta caggtcaagt
    36481 tataaaagct gatgaagctg aaaaaatagg gctagtaaat agagtcgttg agccagacat
    36541 tttaatagaa gaagttgaga aattagctaa gataatagct aaaaatgctc agcttgcagt
    36601 tagatactct aaagaagcaa tacaacttgg tgctcaaact gatataaata ctggaataga
    36661 tatagaatct aatttatttg gtctttgttt ttcaactaaa gaccaaaaag aaggaatgtc
    36721 agctttcgtt gaaaagagag aagctaactt tataaaaggg taaaaatcta attaaaaata
    36781 tatttgctgt taactagatt aaatagtatt ttaatctagt taacagaata taaatactaa
    36841 aataacagga ggttataact atgaaattag ctgtaatagg tagtggaact atgggaagtg
    36901 gtattgtaca aacttttgca agttgtggac atgatgtatg tttaaagagt agaactcaag
    36961 gtgctataga taaatgttta gctttattag ataaaaattt aactaagtta gttactaagg
    37021 gaaaaatgga tgaagctaca aaagcagaaa tattaagtca tgttagttca actactaact
    37081 atgaagattt aaaagatatg gatttaataa tagaagcatc tgtagaagac atgaatataa
    37141 agaaagatgt tttcaagtta ctagatgaat tatgtaaaga agatactatc ttggcaacaa
    37201 atacttcatc attatctata acagaaatag cttcttctac taagagacca gataaagtta
    37261 taggaatgca tttctttaat ccagttccta tgatgaaatt agttgaagtt ataagtggtc
    37321 agttaacatc aaaagttact tttgatacag tatttgaatt atctaagagt atcaataaag
    37381 taccagtaga tgtatctgaa tctcctggat ttgtagtaaa tagaatactt atacctatga
    37441 taaatgaagc tgttggtata tatgcagatg gtgttgcaag taaagaagaa atagatgaag
    37501 ctatgaaatt aggagcaaac catccaatgg gaccactagc attaggtgat ttaattggat
    37561 tagatgttgt tttagctata atgaacgttt tatatactga gtttggagat actaaatata
    37621 gacctcatcc acttttagct aaaatggtta gagctaatca attaggaaga aaaactaaga
    37681 taggattcta tgattataat aaataagaat ttgggaatta aaagtttaaa taaaattgtt
    37741 taaaaaacaa tttcggatat atgaaaaatc taatttaatg ggggtaatga atatgagaga
    37801 agtagtaatt gccagtgcag ctagaacagc agtaggaagt tttggaggag catttaaatc
    37861 agtttcagcg gtagagttag gggtaacagc agctaaagaa gctataaaaa gagctaacat
    37921 aactccagat atgatagatg aatctctttt agggggagta cttacagcag gtcttggaca
    37981 aaatatagca agacaaatag cattaggagc aggaatacca gtagaaaaac cagctatgac
    38041 tataaatata gtttgtggtt ctggattaag atctgtttca atggcatctc aacttatagc
    38101 attaggtgat gctgatataa tgttagttgg tggagctgaa aacatgagta tgtctcctta
    38161 tttagtacca agtgcgagat atggtgcaag aatgggtgat gctgcttttg ttgattcaat
    38221 gataaaagat ggattatcag acatatttaa taactatcac atgggtatta ctgctgaaaa
    38281 catagcagag caatggaata taactagaga agaacaagat gaattagctc ttgcaagtca
    38341 aaataaagct gaaaaagctc aagctgaagg aaaatttgat gaagaaatag ttcctgttgt
    38401 tataaaagga agaaaaggtg acactgtagt agataaagat gaatatatta agcctggcac
    38461 tacaatggag aaacttgcta agttaagacc tgcatttaaa aaagatggaa cagttactgc
    38521 tggtaatgca tcaggaataa atgatggtgc tgctatgcta gtagtaatgg ctaaagaaaa
    38581 agctgaagaa ctaggaatag agcctcttgc aactatagtt tcttatggaa cagctggtgt
    38641 tgaccctaaa ataatgggat atggaccagt tccagcaact aaaaaagctt tagaagctgc
    38701 taatatgact attgaagata tagatttagt tgaagctaat gaggcatttg ctgcccaatc
    38761 tgtagctgta ataagagact taaatataga tatgaacaaa gttaatgtta atggtggagc
    38821 aatagctata ggacatccaa taggatgctc aggagcaaga atacttacta cacttttata
    38881 tgaaatgaag agaagagatg ctaaaactgg tcttgctaca ctttgtatag gtggaggaat
    38941 gggaactact ttaatagtta agagatagtt ttagattata atatttacaa attaaatatt
    39001 taattatgaa tttaacctgt aagaataact atttgttatt cttacaggtt tttatagtta
    39061 aaaataatta ttatctatta aacaaaaata gtgtaaaata tataatatca tgattttgaa
    39121 gatataaaaa agtaggaaga tataaaagaa agtaggtaaa agtttgttta aaaaagagaa
    39181 tcaaagatat aatcttatat cgtatacaaa tgaagaagaa atgactttaa aagaagtttt
    39241 attggacaag ctaaatttct cagttaggtc attatcaaaa atgaagaggg aaaagagtgt
    39301 tttagtaaat ggagtatata aaaaaccgag tttaaaggtg tatagtggtg atttaataga
    39361 agtaaaaata gacgaggaaa aagcaaattt tgaacctcaa gatttaaatt tacagataat
    39421 ttatgatgat tttgatataa ttatggtgaa taaacctccg tttatggtag ttcacccaac
    39481 aaaaagccac tatgataaaa caatagcaaa tggtattagt tactatatag ataatcaaaa
    39541 agaaaatgta aaaataagat ttgtaaatag gttagatatg aatacttcag ggttagttat
    39601 agtagcaaaa aatgcttatg cacatcatac tttgtctaca gcaatgagtg aaaataaagt
    39661 tgaaaaaaag tatataacag tagttgatgg aattataaaa gaaaatgagg gaactataga
    39721 tgagccaatt tatagaccta cagaagattc aataaagagg ataatagatg aaagaggaca
    39781 gtcatctgtt actcactata aagtaataga aagactagaa aatgcaactg tattagaagt
    39841 aagcttagaa actggtagaa cacatcaaat aagagtacat atggctcata taggtcatgg
    39901 aataataggt gatgagttgt atggttatgt agatgaagat ctaataaata ggcaagcact
    39961 tcatgcatat aagctagagt ttgaacaacc aagaacaaaa gaaaaattga aatttaaagc
    40021 agatatacca gaggatatga aagagttaat atcgaaatta agataatggg gtgatatata
    40081 tgataataca taaatttata atacatgttt tggacaaaaa tagtgatgtt ccaatattaa
    40141 atgactttga aggcaaagtt aatcaagaag tagatggttt tttccagaaa gctataaaaa
    40201 gaattgcaaa agatgaggat ttaagaaaag gtgtttttaa agattataat gacaatttaa
    40261 ttaaaaactg ttgtgaacaa ataatatatg atgaaagtac ttttttgaaa aattctaaag
    40321 aaattgcatc ttacttgttt gatgttatga aaattaatgc tgcactagaa tcttgtgatt
    40381 tggcaatttg cttatacact attaaagatg aaaagagtgt agcaatactg aaattagatt
    40441 ataaaaagtt gtacactcat tcaattgaat ttgtggatga taaatttaat attcaaatgg
    40501 tttcaaatga aattggtatc ccagagactt taagacaaaa gcaaggagct ttgattagtc
    40561 taagtggtat aaatgatgag tttcatctaa ggcttttaga taaggatgct gaaaaagaag
    40621 ggtcagaatc taagtttgta acagaatttt taaatgctaa aaaaatagat gatgataagt
    40681 acaagaccaa ggtatttaaa aatacagctg aaaattggat aaccaatgct cttagtaatg
    40741 atataaagca agctgaagat gtaagaagta tattaaatta tacactgaag gaaaaacatg
    40801 aagttgatat aaatgacttt gttgataatt caattaaaga tgatgagtta aaggatagct
    40861 ttaaagagca tatggaagaa aaaggtcttg acgaaagttt tagtatagat aaaaaatggg
    40921 ttgagaaaaa gcttaaaaaa agaagtataa aaacggataa tggttttgac ataaaaggga
    40981 atctaactga ttttgaagac ccaatgaagt atactgtaaa acaaaatcaa gatggaacta
    41041 tagatataat aataaagaat gttacgtttt atgaagaaaa gtaatttata tacttagtat
    41101 ataaattaaa tataagagcg tgtattttat atattgtaaa taaatgtaat ctagtctgtg
    41161 cgaactctaa tataatttat tatgtagaag tttacacaga ctatttatat ttgtagacaa
    41221 aacgatacta tttgttttct tcgatatatt tacatatatc accaatacat ttaaagtttt
    41281 cagcttcctc gtctggtatt tctattccaa attcatcttc aagggccatt ataatttcaa
    41341 cagcatctaa tgaatcagct tctaagtcgt ccattaaaga tgcttccata gttatctcat
    41401 ctaaattgtc tacccctaat tgttctgcta ttatttcttt tattttctca aacattttaa
    41461 gcctcctaaa gcagttttaa ttaattttaa tgttagttta atataatatc aagaattttt
    41521 caatatggaa tctataaaaa ataataaaat tttataaatg tagtaataaa gtattatttg
    41581 atgaataaac tttattgata acaaatataa cttaggagga aatgctatga aatatgtagg
    41641 actattacta acttcagtag gaatgttttt acttatagca gtaaattttt attataattc
    41701 aataacttta gatatgcaac gtatagagga ttatgtaatg gagaccaatt taatccttga
    41761 agatgtagct gaaaaggaga gttatgtatc taatgaaaaa gaagattaca tatcaaggtt
    41821 aatgcatgta aagaaaggaa tagaaaattc aaaaacatcc ttcttgatag aaagatataa
    41881 ggagtacaaa ataaaatcaa tagaaagttt aatctatact atatcagagg agaaaaaaga
    41941 ttatctggat gaagttgata gatacaataa acttggtgaa aaagaaataa ataaactaat
    42001 caataaaaac tttttagaag taacttatct gtctattact acatatattt aattaaagag
    42061 acaaaactta gtctcttaat gattcaagga ggattagtta tgacaaaatt agaagacaat
    42121 atggaacgtt tctttggagg atgcgaagga ttttttggga ataaaatgtt gataataata
    42181 gttatagtat tcttactatt atgcacagac attttagaag acttattatg cgatgacaat
    42241 atatggatat gggttatatt aatagtattg ttattattta acttcgatga tggttgttgt
    42301 tgctaaaaaa tattgattat taaataggta aaaccagtaa cttatacaag ttatggtttt
    42361 acctttttta gttcaaatta aaaaatttaa aaaaatagta aaaatacatt agcaaaatgg
    42421 aaaccaaatg catagtatat gttaggagcg aaaagctcaa caaaatatca acaggaggta
    42481 acgtataatg ttagatagat tctttggaga agaaggatgt tttggtggag gaggatggtg
    42541 gataatagta ctattcttcc tattcttagc ttttggagat agctgggcag aatttgacat
    42601 aatggcatgg ataccattcc taatagtttt attaatactt tgctgctgtg gtggatgctt
    42661 agaataagaa cacagttatt aaaaaaagga gggctttgtt atgttagata gattttttgg
    42721 agaagaagga tgctttggtg gaggaggatg gtggataata gtactattct tcctattctt
    42781 agcttttgaa gattgctgga gagacattga cataatgtca tggatacctt tcttaatatt
    42841 attgctaata acttgttcat gtggtggatt ctttgatggt gaagtaggtt gcggctgcta
    42901 atacttaaat cattagaata aaaaaatgct ggtattttat accagcattt ttttatttta
    42961 ttttttaata tgatttaaat taagaatgaa tattattaaa tttgttgaat atagggtata
    43021 atataaaata taatgtattt aaatgtactt gcttttatgg taaaataaaa acttatataa
    43081 atgtagttaa aataggaacc ttcaaaaatt tggttcagtt ttagataaat ttagtaaaat
    43141 aaggaggatg aagatgaaag gcaatataac gataaaagat gttgctaaac aagcaggagt
    43201 gtcaatatct actgtatcta gagttataaa tgattcaaaa cctgtaactg atgaagtcaa
    43261 acaaaaagtt ttagaggtta taaaagagac tggatatata ccaaatccac ttgctagaag
    43321 cttagtaaca aagaagagtc aattaatagg ggtaatagtt ccagaagttt cagattcttt
    43381 tgttaatgag gtgttaaatg ggatagaaga ggttgctaaa atgtatgact atgatattct
    43441 tttagcgaat acatactctg ataaggaaca agaacttaag agtataaatc tattgagagc
    43501 aaaacaagtg gaaggtatag ttatgatttc atggatagtt gaacaagaac atatcaacta
    43561 tatacaaaat tgtggaatac cagcgacata tataagtaaa actgctagaa attatgatat
    43621 atatacagta agtactagca acgaagaagc tacttttgat atgacagagc atcttataaa
    43681 gaaaggtcat gaaaagatag cttttataat gactagtaaa gatgatactg ttttagaaat
    43741 ggaaagactt gctggttatg agaaagcact ttcaaataac aatatagaat tagacaagag
    43801 tttgattaag tatggtggaa ctgattatga gagtggatac aatagtatga aagaactatt
    43861 agatgatgga ataatacctc atgcggcttt tgtaacaggt gatgaggctg ccataggtgc
    43921 tataaatgct atatgtgatg ctggatataa ggttccagaa gacatatcag ttgcaggatt
    43981 taatgatgtt aagatagcta gaatgtatag acctaaactt actacagtat atcaacctct
    44041 atacgatatg ggagcagtag caataagaat ggttataaaa ttaataaata aggaattaat
    44101 tgaaaataag aaaatagagt taccttatag aattgttgat agagaaagtg ttacagaaag
    44161 aaaaaaataa aactattaaa atcaatcagg tagtgcctta ggcactacct gattttttat
    44221 gtcaataata tcaaatttaa taatagatta actaaaaata attatctaat tgcttaaata
    44281 gtttattttt atctattcat gaggattaga ctttttagtt ttcttaaata aacttttaga
    44341 ttttttttgt tgactacctg gtgtattttt tggtgcaggt gaatttgact tacctttagt
    44401 aggtttagcc ttcttagttt tagctggttt agtatctctt tggttttctg catctgagat
    44461 tttttccatt atattatcca gttttttgcg ttgattttca tctaaaaatg ctttgaattt
    44521 tgatactact tcatctctgc catctagatt cttacctatt tttataagtt cctccataag
    44581 ttcattttct gattttcctt tgtaactatc agccatcttt tctattttat ccttgtcaat
    44641 atttttttgt ttagccattt tttctaatga ctctgtatct aattttttca taaaaaaacc
    44701 cctttctata aatatatatt gaattatatt catactattt atatatagaa ataatattga
    44761 agtggtgaat tgtgagtgat atataatata aataaaaatt cttatagata atatatatgc
    44821 actgagcttt aaaaatggaa cattaaaata tgaaaaacat actttaatat agggcaatta
    44881 tataatataa gggggaattg tcttgaataa cttactattt ttgattggag tgattgcatt
    44941 gagtaatggt aatatctcta tatttgatga taaaaataaa tcaaaaggaa ataatagagt
    45001 tagaaaaaac aaaaaaaatg caaatgataa actttcacag tctacacatg gcaatttaag
    45061 gtttgatgca aatgatataa aaagaggttt aaggctcatg gatttaagtg aagaagattt
    45121 agaaatggga atggaaataa taacaagaac taaaaaatac atgtcaagag atgaaagaaa
    45181 aatactaata aaaatagaaa gtgttttaga tttagttaga ggaataaaaa aattaaataa
    45241 tatagatatg gtagatacag aagatgaaac ggattttttc agaaaaatgg atagtgatga
    45301 taaaaagaat atgatgataa aggaaattat agatgtattc ccagaaaaaa gaaaaaattc
    45361 agttgaaaaa gctataggaa tgaaaaagaa gatagattta tttgcagaat tatttttacc
    45421 agatgacttt ggtgaaggtg gatttagttt gagctctttg gcaaatataa acaatcttgg
    45481 tagtatgaat aatctcaaat tgttaggaag tcttttaaga ggtgatgata gtaataatga
    45541 tgatgaagac aataatgatg agttaaatta tgaagacgaa gaattagatt gtgaagacaa
    45601 agaattggat gatgatgagt taacagatga aggtgaaatg gaggataatg aagatgaatt
    45661 agtagaagat aagaacacag gctatgaaaa tatagaaaat gatgaagata tagtatacga
    45721 tgaggaacta tacaacatta atgagcaaga atccgaatac aattataatg aaaaaaatac
    45781 taaaactaga gctaagaaaa aacgataatt aactaaatac ataaagaaaa aaggaagaaa
    45841 aagtaatgat agaataagat tatctcaatt actatataaa accactttaa aaaattcaaa
    45901 atttattata taataataat atgaaatcct gaaacatacg ataaggcttt tttaaattca
    45961 acctacaaat gaaatacggg agaccgtgtc tggtaaatta taacatgcct agttagtttg
    46021 gacgttaaag gttactggca agtcacccac ctgggagtgc ctagggtgtg aatttactta
    46081 gccaccggtg tttcgggaca aaaaaagtgc tactatttca aatagtagta ctttttttat
    46141 taatatgcat ttttctacta aatacgccta attattgata aattcaaaaa gcaagtaaca
    46201 attaagatta taaaagcata gtattaatta ggcttcaaaa agccaaagac ttaataagaa
    46261 tcgcttacag ggagggcaat gaaaaatgca agattataaa aaaaataaaa gaagaatgat
    46321 gaatcagcca atgtctacaa tgaatgaaga agaagtgtat acagatgaaa taaattcaga
    46381 agacatgaga ggttttaaaa aatcacacca tcataatgga tgtaatactg ataataagtg
    46441 tgagtgccat gatgattgca atccatgcaa cccatgtaat ccatgtaaac ctaacccatg
    46501 caatccatgc aaacctaatc catgtgatga caattgtgga tgccatgaca attgtaaatg
    46561 tgattgtgaa ccatgtgaaa tggattcaga tgaatgtttt gaaaacaaat gtggaccaga
    46621 atgctgtaat cctatatctc caagaaactt ctctgtatca aatgcagtgc catttgcaat
    46681 agaggctaat agaatatttg atactatgca attccaaaca tttacagatg caacaggacc
    46741 aaatggagag ccattaactt ttgaaacaga agtagtagaa gtatttggtt cagttccaag
    46801 tgcaggtcaa gcaagtgtaa ctatagaaaa aatatgctta agtaatgatg gaatcgttat
    46861 agacacagga atgacaactt tagaagattt cgatttagac ccattaggag atatagtagg
    46921 aagaaactgt gaaacaactt ttgaatttgc agtttgtgga gaaagaaact ctgagtgctg
    46981 tagacaagga aaaggcaaat cagtagctta taaacaaaga ggattaactg tagcagttcg
    47041 taatttagta ctagagctaa gaggtagatg tggatgtaca gagttcgttg cattagcttt
    47101 cccagcagtt agagcaggag gtggatgtaa gagaagagtt gattatgtag aatttacttt
    47161 taacacactt tcagcaccaa tatgcttgcc agctgacgga agagctgtta ctttaagaca
    47221 agaatatcaa actaacttaa ctgtagattg tataggaaaa tctatattaa aattagaatg
    47281 caacgaatgt tgtgaacctt tctatgaatt aattatacca aatgatatag atttagtact
    47341 ttgcttacaa gaaacagtta gcacattaat aagtgaacaa atagtagttt tagcatcacc
    47401 aaatccaatc caaccaagac ttgttgatac tttctctaaa gtatgtgatt tttcgcaatg
    47461 tggacctaat catggaagtg gaaagccaag ttgccacaga tagataggta gatatataga
    47521 cagtttaaat tataaataaa aatcatctaa ggaaggctac caaagtgtat aatttacatt
    47581 ggtagccttc acgtttttat aactagcgta tagattttag tgatttaaaa agcactatag
    47641 tatgtaatag acaagtaaag attgatacta tcgtcattgt gtatatgtat gcataaatat
    47701 taagtcctgg aattggaaga aatacatata aagctattag ttgaattaac atgccagtaa
    47761 tagtatttat acttgaagct aattcttttc ttattgaatg taaaatgcca gatagagttt
    47821 gatttaggga cataaatagt ggaactaaaa acatagcttt tagatattct cctgcaagtg
    47881 tatttttaaa tactaatata cataaatctt ttccaaagaa ataaaaaaat attgatgata
    47941 gtatgcctac aaataaagta agaagtatgg agtatttgat ttttttaatt acactcttac
    48001 gctttcttag agccatttct tgtgaaatag ttggtattaa atttacaata agcgctgaac
    48061 caacagtaaa aggtaaaaat ataaaaggca ttaccatccc actgacaata ccatacatac
    48121 ttaaagattg ttgataagtc attcctgata atgctaatct tgatggtatc atcatagaac
    48181 ttatagattg caaaagtatg tttgacattc tattacaagt tatgggaata gacattttta
    48241 atgtttccat agaagaatta taaaaatctt ttatgcttat aatataccta ttgtcaaatg
    48301 atgaatctcg ccataagcaa ataagcataa atataatatt actcaactca ccaatcgata
    48361 tacctaatag agctatataa caattcatag atttattatt tatgtacata acaagtaaaa
    48421 aaacaaataa tattttacca atttgttcaa tgatttgtcc aatagcaggg atttttacat
    48481 tctttatgcc atagtaatat cctcttagta cgtttgaaag agttattata actatagcag
    48541 gacaaacagc tagtataaat agatttaatt tagcatcttt taaaaattta agtgataaaa
    48601 aagaactatt gaaagatgca actatagata taattagtgc tacgaaaaat gatatatata
    48661 aagttgatat aaataaagca ttagtattgt gtctatcgtt taaagctttt ctctttgcaa
    48721 ctagacaact aagtgcagta ggtatacctg ttgttgtaac agctaagcaa atcatcaaaa
    48781 agttaaaaat catatgatag atacctaaac ctgtttcacc tagtgctctt gataagaata
    48841 ttttatataa aaaaccaaat attcttacaa taaaattgga tataaataaa ataactgttg
    48901 atagtactaa ataaggtact ttcaaaaaaa tcacctcctt atcttttaaa tatattcaca
    48961 aggaggtgta aaaatttata attttataaa ttctggtttc aatttattaa atttagatac
    49021 atatttaaat cccatatttt ttagtaatga atatatgtag tcaaactcac atgcaacttg
    49081 acttatatga tgtgaatctg aacctgtggt tatgatttcc cctcccaagt ctttgtacat
    49141 ttgaagtata tacttagatg gggttaggtc tggaagatta tatctataac aagaggtatt
    49201 tatctcgata cctttgccat cataaatagc ttgtttaaga gtttcttcaa ttatatcaga
    49261 aaatagtcta tcatctaaaa tagtgtcata aggtgcatac cttttaatca aatctaaatg
    49321 acctaagaca gagtaatctt tataattctt aacaatatta tataaataaa gatagtaatt
    49381 ttcataaact tcatgttgag ttttatcttt aaaataatta ccaaggtata agtccattgt
    49441 atctatagca tggatagaac atattataaa gtccaatgga tattgatgtg cttccttttt
    49501 gtatgtatcc attaattgag tttgaactcc aaattcaatt ccttttttta ttgatatttt
    49561 atctttatat ttgctttgaa gagtctctaa actcttaaaa taatcttcgt agacaattga
    49621 aaaagaatca tcagcatata catcatagtc aacatggtct gtgaaacaaa tttcctccaa
    49681 accgagttca atagattttt ttaccatttc ttccattgta gattttccgt ctgtagagaa
    49741 acttgagtgc atgtgatagt cgtaaaacat aaatatttcc cctttttata aaaattttgg
    49801 tattatatat acatactaaa taatatcaaa tatacataaa agcatcaata aaatataaat
    49861 acaatgagcg gtgataaatt tggaaaaata cagaatagat ttaaatgaga aaaaatcaac
    49921 taaatatata cagatattta atcatataaa agaattgata ataaataaag agttagtaga
    49981 acatgaaaaa ttgcctccaa taagaaaact atcaaatttt ttacaagtaa ataacactac
    50041 tatagttaag gtatacgagc ttttagaaaa tgaaggatat gtatataaaa ttatagggag
    50101 tggtactttt gtatcaagtt taaattctta taaaagcggt atagataaca ggaaaaataa
    50161 gattattgtg caaagagaag atttaattca ttttgacaat gggaatccat ctaatgatat
    50221 gtttcctatc gattcattta aaaatgctgt aaatatggca ttatctaaag atggtagttc
    50281 aatatttgaa tatgatgaag gtcttggctc tgaagaatta agagaaaaaa tggtagagta
    50341 tctaagtgat ggaaatataa aaactactaa ggaaaatatt caaataatat caggtgctca
    50401 acaaggtata gatatagttt gtaaaggact tataagttat tcagatgttg tttttatgga
    50461 agaaccttct tacaatggag caattgaagt gtttaaaagt agaggtgcaa aaataatatc
    50521 tatacctatg ttagatgatg gaattgatat aggtatttta aaattaaagt tggaaaaaat
    50581 aaaaccaaga cttatataca ttatgcctaa ttttcaaaat ccaactggaa tatcttactc
    50641 aacatataaa aaaaagaaat tgatagaatt ggcagaagaa catgattttt atataataga
    50701 agatgatttt ataagtgatt ttgtttttga atcaaaggac aatagaacaa ttagaagtta
    50761 tgatgataaa aatagagtag tatatataaa aagcttttca aaaatactta tgccaggtct
    50821 taggatagga attgtagaaa tgccaaatga gttgttaaaa aaagttttat gggctaaata
    50881 ttcatcagat atatcaacac caggtttaat tcaaaaatca atgtattact atatgaataa
    50941 ttttgattgg aagaattatt tgagtcatat agagaagata tatactgata agtataaatt
    51001 ggcaaaaaac ttgattaatg acaaattgag tggtaaatta aaagttagaa aatcttgtgg
    51061 aggaataaac ttttttttag aattaccaag aggatataca tctcaagcat ttacaaattt
    51121 tatgttaaac aaaggagtgt caatgcttcc agggacttat ttttttgaca atctagtgga
    51181 tgatagattc tttaggataa atatagctcg tccaagcatg gaagaactag aaaagggaat
    51241 atctataata agtgataata tagatgagtt tttttgtgaa tataaaaaca agttagatat
    51301 aaaaagcaat aaattatttt attaaataaa tagaggtttt ttaggaggaa aaaatgtttg
    51361 acaagaagaa attagatagg attaatgaat tagcaaagaa aaataaagag ggaatccttt
    51421 ctgctgatga aatcaaagaa agagaaattt taaggaaaga atatttagaa aactttagag
    51481 cccactttag atcaagacta gatagtgtca aagtagtttc accagaagaa tatgagcaat
    51541 acatgaaaaa caataaaaat tagaacttag taggaggaaa atatgaactt aaagtacgaa
    51601 tttaagaatg cttgggattt tgaaagaaaa gaaaatacta ttgaacaaat tatgcaatat
    51661 tctagcaatt atatggagtt tttaagtaag tcaaagactg aaagactttc agtaaaagaa
    51721 attataaaat tggctaaaga aaataactat atttcaatag atgaagctat ggaaaaagga
    51781 agcataagtt gtggtgataa aatttatgtt ataaataaag agaaggcagt agcacttttt
    51841 gtaataggta aaaattatat agaaaaaggt atgaagatta taggaagcca tatagattcg
    51901 ccaagattag atttaaaacc aaatccactg tatcaagaga gtaatctagg tttttttaag
    51961 actcattatt atggtggaat aaaaaaatac caatggacgg ctattccact tgctttacat
    52021 ggtatagtta tattaaatga tggaacaaaa gtggacatat ctattgggga agaagatagt
    52081 gacccagtat tttgtgtaac tgatttattg attcatttgg ctggagacca aatgcaaaag
    52141 aaactatcag aaggaattag tggagaagct ttaaatatat taattgggaa tatgccttta
    52201 gaagatgaag aaaaagaacc tataacagca aatatattaa agattttaaa tgagaaatac
    52261 aatatagttg aagaagattt attaagtgct gaaattgaag tagttccagc tggtaaggct
    52321 agagatttag ggcttgatag gtctatggtg ttgggatatg ggcatgatga tagggtatgt
    52381 tcatatgctg ctgtaaaagc tatactagaa actgaacaac cagaatttac ttcagttgca
    52441 ttatgtgtag ataaagaaga aattggttct aaagggaata caggtatgca ctcaaagttt
    52501 tttgaaaata ctgtggctga actgattgct ttagaaggag attattgtga tattaaagta
    52561 agaagagctt tagcaaatag taaggtatta tcagctgatg tttctgctgg atatgaccca
    52621 aattttggag aagcatatga aaagagaaat tcggcatata tgggaaatgg agtagtttta
    52681 actaagtata caggttcaag aggaaagagt ggatgtaatg atgctaatgc tgaatttatg
    52741 tcagaagtaa agagaatttt taataaagga aatgtagtat ggcaaactgc tgaacttgga
    52801 aaagtagacc aaggaggagg cggaactata gcccatatat tggcaaatca aggtgcagag
    52861 gttatagact gtggtgttgg agttttaaat atgcatgcac cacatgagat tgtctctaaa
    52921 gtagacatat atgaaatgta taagggatat aaggcatttt ttaatataaa tttataagta
    52981 aaaatataaa tgtaataagt gaataaaggc tgttgtataa acaatttaat ctgttgtaca
    53041 acagtcttat ttttatgtaa aaatagcaat ttgtcacact agagaaaata aaagaaaata
    53101 ctgtcaaatt aaaaattatt ttaaaaaaaa ttgacaacga tttcatcttg ttataatatg
    53161 taataaagaa cttgttatat aatgttataa aaatgttaca tagggaggtg agcaaaatgg
    53221 atgaaaagag acaaaaaaaa gaaatggatt tagaagtaaa ttcctttgtt cctttatatc
    53281 aacaactata tgacaacata aaaaaacaaa tagcatctgg catatataaa ccaggagata
    53341 aacttccatc tgaaggagac ttatgtaaag aatttaatat aagtcgtata actgtgagaa
    53401 atacgacttt tttatataaa atagcaaaat aacagtgttt gagcaaaaaa aaagaatgtt
    53461 ttttatcgtt ttgccacctg tttgccacca taactttttt cggtggcaaa ttattgtaaa
    53521 atgccctcca aaatatctat tgtttcactt tccattttac ttgtaacatg tgaatatgtg
    53581 tccatagtgg ttgataattg actatgacct aatctttgtt gtatatattt tacattagct
    53641 ccattttcta ataataatgt ggcatgtgta tgtcgcaagc aatgaaaatt aaagttaata
    53701 tttagtttct tgttaatagt tcttatagca gcgtcaatat tgttgtgatt tacaaatgag
    53761 ccatcttttt ttctacaaac ccaatcatac tcagtttctt tataccattt tccaatttta
    53821 attttttgtt ttttttgatt caatttttcc tcttttaata tcctagacaa agtatcacct
    53881 attttaatat ctcttattga tgtttttgtc ttaggtgatg ctaattcaaa ttctgaaact
    53941 tttctcttta ttaaattttt tctaactttg attatattat tatctaaatc aacattatcc
    54001 caacaaagac ctaatatttc tccttttctc atgcctgtat gaaaccctat aagtagagga
    54061 atatagatat ttgtattttt aggatatatt tctagtattt tattgaactc atctagtgtt
    54121 atagtcttgt tatctgactc attttttacc tttaaaacat tttttggtat actggcatat
    54181 tgaacaggat tttccttaat gagtttgtaa gggtaaacag cagattttaa agcagcattt
    54241 aatacaacat aaatcgcttt taaaactcct tttgtgtagt gtttttcttc tccgttttgt
    54301 gtgtatgtct cttttgattt attatttaaa aattcttgaa taatagctgg atttatagat
    54361 tttagcttac atttaccaag tctaggttct atatgatttt caattaaatt tctataactt
    54421 tcctgagtat tgtatttgca attaagaagt acatactctt tgtaccaaaa gttaagatag
    54481 tctgataaac tcatatttgt ttcatcaaac actataccag cattttcata ttcatttatt
    54541 gcatcacgga gcgatttttc agcttctttc ttagtgtttc caccaactct ttctaccttt
    54601 tttctcttgc catctactat acctgcatca aagtagtaat accacttctt tccacgtttt
    54661 cttacgccgc ctttcataaa atctctcctc tcaaaagctt tttttatgta attatataat
    54721 aacatatatc aatttaaata aaataaataa aaaagactat aagaaacaaa gttttatgtt
    54781 tataattaat agtctttttt atttagatac atatttaatg ttttttatca cgtgattcca
    54841 gcactttttc tgccaaataa acaactattt tttcatactc aatatcagtt tctaaagaaa
    54901 agtcaacaat agcaggtatc gtcatatctc ctgcatattt attacctaac caattttcaa
    54961 ttaattccaa ttcttctttg cttaattcaa attttttctt tttattaaaa cttaagttca
    55021 atttattcac ctcaaataat attatatatt aaaaatagta tttgatagaa acattcgaat
    55081 tatttatgta attttctttt tttaatatat tcatcagcaa aataatttac taaatatttt
    55141 tcctccaatc ctaaagctat ttctaattca ataagagcag ggatagttaa atctttattc
    55201 tcattatttt ccaacctaga aatttgactt ctgtggcaac caactctttt tgctaactct
    55261 atttgtgtta atttcttctt ttttcgtaac tcttttaaca tatatttaac ctacctttta
    55321 gataatttta tatatgttag tttgtgtaat ttcttgtaat aaatgtgcaa tattcgcaca
    55381 ctttttgttg gaaatttgtg ctagaatgta gttaagaaat aactttatct agataaagca
    55441 aaaataatag aagctataaa atataataat attttacagt tattttatag ttttaagctt
    55501 tgaaaaagag gtggttgtaa ctatttttaa gaacgtatgt ttcgtggaat taataaataa
    55561 aatattttat aggggatgat atatttgaat aagacgaaat attatgatat tttaaagtta
    55621 aacttattaa tgaaaaagtt gaaagaattg gataaaaata aaatcaatga atataaaata
    55681 aaagtgaaag aaatacataa aatcaataaa aaagaggaat gattcctctt ttttattata
    55741 ttcattttca gaaataaact attttttatt tttttcgtct agtaaaaata attctgcaac
    55801 ttttaatgct ttttctcttg cgtctgggct tagctcgcta aatatattaa aaacttcttt
    55861 catatcttcg tcaagataca tattctcaat aagctccttt tctgttttaa aattttcagc
    55921 atcataatct ttttcgtttt tatttataaa taagctattt ctaacatcag ttcttcctaa
    55981 taaataatct gtagacacat caaaatagtt tgcatattct tctattgtac ttttcttagg
    56041 ttctcttaaa ccattttcta tccttgatag tgtagatttg tttatatgta aatcctcgct
    56101 taatttgtct agcgagatgc ctttttcttc tctcaattct tttatcctat tcaatttgca
    56161 caaccccttt ttatattaat tccaaaatag caacttttat ttatattata gcaacaaaat
    56221 taattattac aatttttttt gctaaaaaag caacaaaagt attgactata atcacaaaac
    56281 ttgatattat ataaatatga agttgccaaa atagcaaaaa ggaagtgatt taatgtactt
    56341 aaatagatta gaaggattga tgaaggaaaa tagacacacc caaaaaaatg tggcagatat
    56401 attaggtctt agctcatatg gttttagatt aaaattaaaa ggaaaaaacg aatttaaagc
    56461 aagtgaaata aaaaagatat ctaaattata taatgtatct gcggattatt ttttttcaga
    56521 tgaagttgct aaaatagcaa taaaagaaga aaggggcaat aaataatgaa gaatctaacc
    56581 ataatcaagc aaaataatca atttttagtt gaaagtagag aagtagcaga attaatagaa
    56641 aagaagcacg ataatttatt aagagatata agaggataca agaagatttt agaggactca
    56701 tcaaatttga agagtcaaga tttcttcata gaaagtactt atataaatac tcaaaataaa
    56761 attcaacctt gctacttatt aactaaaaaa ggttgtgaca tggtagctaa taaaatgaca
    56821 ggtgaaaagg gaattatatt tacagcgatt tatgtaacta agtttgaaga aatggagcga
    56881 gagttaaaag aacaacaacc taaattacca actacatata aagaagcact gcaacagtta
    56941 ttaatcgaag ttgaagaaaa agagcaatta caattagaaa atcaagtaat gaaaccaaaa
    57001 gcagattact ttgatgctct agtagaaaga aacttgctaa ctaatataag agatacagca
    57061 aaagaacttg gagtcaaaga aaaaacattt gttttatggt taatagagaa gaaatattgt
    57121 tacagagatt taaaaggcaa aataaaacct tactctaaca agatgcagta ttttgaactg
    57181 aaagaattta caacaccata cggacattca gatactcaaa cattaataaa tccaaaagga
    57241 agagaagcat ttagattatt acttataaag gatggactgg taaaagaaaa agaatatcaa
    57301 ataactttat taggctaaaa ttgaaagtac tttgaaaatt aaagattatg gaggtagtta
    57361 caatgagcga agacatattt tatggtataa aaaatactct tgatgaaata gcagaggttc
    57421 aaattaaaaa taaacaaggt gtgttaaaag aagttggaat gttaataagt ggtgaggaca
    57481 attcttgtat aacgcattgt ttagatgaag atttaattaa gttttacata aaagaagagg
    57541 cagtattgac aatagataaa gatagtcatt tgttatgtat gcttgatgct ctattttata
    57601 actttcttga taaataataa atacagaata ttcttgaaat ggtggtgaag aaattgggta
    57661 atatatctaa ctttaattta gataaacaag aagataaaag ttttaatgac ctggataata
    57721 tatcaatttg tttttcagaa ggtattcgta aagttgtaga aatgaattta aacaactata
    57781 aaaataaaat ctcaaaatac ttaaatgaaa cttcgaaaat agaattgttg gaaccaaaag
    57841 aattaacaat tgttataagt aaaggttatc ccgattatct tatgtctgtt gaagaagcaa
    57901 gtaaaagatt gaaaatagat aaagtatttg gatatgagtt aataaaaaat ggacttttga
    57961 agtcagttga tataggggca actaaagttt ctagttatga attagatgat tttataacta
    58021 ggaatcaagg aaaaaacatc aaagaaatgc ttagagaaat gaaagaactt agagaggggg
    58081 tgatttaatt ggaactagta acatacagaa acaagcttgt tttactaaaa gatggagaaa
    58141 agattgcaac tataagttta aaaaggaaat ttctcagcaa cagacttaaa ttaaaaataa
    58201 gataggagag ataaattgaa aataatttat aaaaacaaag tttacaaagt agaacaagac
    58261 aaaaagttat ttagaattac atactatgat gagcagagag gtagtaagaa gtttaataaa
    58321 gagaagaaaa taaaaagaag tgttttaaca agagatatag agttagttaa cttgtattta
    58381 ccagcacatt taaaaataaa ataagctata aataattaaa gaaaaaggtg attagatgga
    58441 aatagaacaa gcaacaatac gcctgcctag agaacttaaa gacaagcttc taaaacaggc
    58501 aaaagttaaa ggatatacat taaaagatat gatagttttt attctaaagg attatcttca
    58561 aaatatttct caagaataaa ttcaatttct ctacctatag aacgcttatc tttttgagca
    58621 agttgttcga ttttctcaaa aagaagttta ttaattctta gtgtaaatct tttatcctct
    58681 tcacgagtat aaatatcttt attagacata tttatcattc ctcacataaa atttgacgtc
    58741 tttatgacac tttaataata aaataatata aaagaaaagt caacaaaaat gcttgacgtc
    58801 aaatatatga catggtatta ttaaaacaag aagggagttg acgtcaaata tatgacaaat
    58861 gaaagagtta gatttacatt tagattacca gcaccattgc ttgaaaaaat taaaaataga
    58921 gcatcaatag aaggtagttc aatgaactca cttatattac acatactttg ggattacata
    58981 aaagaaatag aaaataagga ggtcaaataa tggttgaatt ggtaaaagaa tttgatttac
    59041 aaacaattaa agtaggaaat gcagtaaaag taaattgcaa aagatttggt tttgaaattg
    59101 attgtatagt agtagtagca acagaaaaag aattaaattt agcatacttt gatgaaggta
    59161 gaggctgtat ggagtatcaa gccttaataa cagaagatat tcaagatggt gattatgaga
    59221 ttaaaatttt atcttaggag gaaataaaat ggctgcttta ataatggtag gtttatttgc
    59281 aatatgttta gtaggattag ttcaaaatag agattaaatt aagggggatt aattatggaa
    59341 agtttaaaaa gaataaaaaa aatggttcaa aaacaattag ttttagctga attagagata
    59401 aacaaaaata gcaaacttta tgaggaactt gaaaataagg atagaggttt aatagatgat
    59461 atacacatga gagaatatct aagagaaaaa gttgcatggg aaagagtaaa atatgctatt
    59521 gaaaatattt taggtggtat aaatttagag attaaatcaa aggaacatga agaaagtgag
    59581 gattacaaga tatttcaatt aattttagaa gaacttgaaa gagataaacc tatagatgtt
    59641 cagatataag aaaagagcca ttgccgtggc tcaattcaaa taaatatatc aaaatttaat
    59701 taagctaatt atagcacaaa cggagggaaa ttatgagtac tttatatgaa ttaactacag
    59761 atttattaga aatagaagaa ggtttaacag aaacaacagg aaatgaaact gaaaaactag
    59821 aggaaataaa agaaataata aaacaagaga tacaaaataa aaacactagg atagtttcag
    59881 taatattaaa cattgacagt gatataaact ctatagattc agagattaaa agactgcaag
    59941 agttaaaaag ggtcaaaaag aatactcttg atagattaaa aagcaatata aaagactgta
    60001 tggaattact tggtactaaa aaagtagaaa cagttttagg aaatataagt ataagaaagt
    60061 cagcaggtag cttagtcata gaagatgaag aaaagatacc tgctatatat aaaacagtag
    60121 agcaagttgt aaaagtagat aagaatatca ttaaagactt tattaaaaaa ggtcatgagg
    60181 ttgaaggttg caggattgaa tatggaacta cactaacaat tccaaaagct aaaaaagagt
    60241 aggtgaggac catggaaact aataatgttt atataaaact tgtaaatata cagagtactt
    60301 taaaagctcc taaaagtcaa tttaatagct ttggtaaata caactatagg agttgtgagg
    60361 atatactaga aggtttaaaa cctattctaa aggaagaaaa agcattagtt atattggatg
    60421 ataatattgt tcagatagga aatagatttt atgtagaagc tacagcaact ttaatagatg
    60481 cagaaacagg agagaaagta tctacaaagg cattagctag agaagatgaa actaaaaaag
    60541 gtatggattt agcacaagta actggaagtg tatcaagtta tgcaagaaag tacgctttaa
    60601 atggattatt ttgtattgat gatacaaaag atagtgatgc aacaaataaa catggaaatg
    60661 agcagaaaaa aaaagaagtt aatgagagtg aattaaatac actatattcg ctaggagaat
    60721 ctatagaaaa agataaaaat agagttgata gtgaagtata taagaagttt ggaaagttag
    60781 cagtagattt gactaagcaa gagtatgaga aagttttaaa tggatataag agcattttag
    60841 agaagcaaaa acaagagtag gtgatagtat tggggattat aagagtaagc aaagacaaag
    60901 ataatccata tgtagtttta aataaaactt gtttggaaga tgtaaaatta agctggcaag
    60961 caaaaggttt acattcatat ctgattagta agcccgacca ctggaaaatc tatgttaatg
    61021 acctttgcaa gagaagtaaa aatggaagag atgctacagc aaatatttta aaagaactta
    61081 tagaaaatgg atatataaca agaaaacctt gtagagattc taatactaat aaaatgcttg
    61141 gagggtatga ttatgaagta tatgagatac cacttgaaaa tcctcagaag ctaaaatccc
    61201 gaaaaactga tttcccggaa accggatttc ccggaaaccg ggtttctcgg aaaccggaaa
    61261 acacggaagt agtaagtaat gactttaaag taaataatga tattactact attgttatta
    61321 atgaacaatc caataaagac aaaaccacct atataaaaaa atactttgaa aaatatatag
    61381 gtgtgattac tcctaataac tttatagagt taatgagtta cttagatgat ggaatggaag
    61441 ctgatgtaat aataagagct gttgatgaag ctgtaggcag tggagttaag aattataagt
    61501 atgtaaagac aatcttaaat aattggatag aagcaggtgt aaaaactgtt ttagaactta
    61561 cagaatatca gaatgaattt gaaagaaaga aaaagagtaa gcaggaaaag aagcagtcta
    61621 atagtaaaac tgtgaatact cataatgtga ataaaaataa gtttgctaac ttcaatcaga
    61681 ctttcactca atatgaagaa aaagagctag atgagattat taaaaagagt cagaaggaaa
    61741 aatttaaata aaattaaact tctaggaagt aaatatcaat atattgcttc ctagaaaagg
    61801 ggaggtataa aatggcgaga atatatgcac aaagaagtgg ttctttaaat gaacaagata
    61861 gattggagtt attaagatta cttgggaaag ctggatatac agtaaaggtt gctagagaga
    61921 agcaaaatag caagacaact tatacttact ttgttgagta tacagaagaa caggaagaaa
    61981 aatagaaggg ggctagttaa atgaatacaa taactttagt tggaagatta gttgcagatg
    62041 cagaattgaa gtaccttcca aattcaggta ctccaaaaat aaccttttca atggcagtag
    62101 atagaaggtt taaagataaa aatggaaata aaataactga ttttattcaa tgcgagcaat
    62161 taggaaaaca tgtagagaat ttagtgcaat atcttgttaa aggtaagcct atatatgctg
    62221 ttggagagtt aaatatatat aattacaaag atgaaaatgg ttgctggaaa tctattacta
    62281 aggttaatgt aaatgcttta gaactacttt ctagtaaaaa tgataataat gctaaacaag
    62341 aatatgtacc accaggatta gacccacaag gttttcaagc aatagatgat gacgatatac
    62401 ctttttaatt aagttaaata atctagggag taattatgca atattacttc ctaggagtta
    62461 aaaaatattg gaggtttaag agtgaaatat gagtgtgaga aagtgttctt agaatgcgat
    62521 aagggaagtt ttgagataaa tgatacaaga gctgaagaag taacattcga gggtacagaa
    62581 atagacaatc tgtttgagag agtaaaatat gaagggactt ttacaataat atctggatgg
    62641 gattctttat tgagagatat attgtggctt gaaatgcgga aagtcttaaa aattataaca
    62701 ggaaaaatga tgatgggggt attaggaatg ataataatta gaagtcaaga taaaactgat
    62761 ttagtaaaag ctgattggat aaatgttgat aaagaatgtg tatatgcaat gtttggagat
    62821 atggataact ttaaaaagat aggtgagtat gaggatgaaa aaagggctat acaagtgctg
    62881 gataatatac aaagatttat tgaaggtgga actagaacag attctataga cagttataag
    62941 gttagaagtt atagaaatag aatatttcaa atgccagtta aatagggagg ttactgaaat
    63001 gttaaaggtt gaaaaatatt ttagtggttc tttaggaaca aatatcatag atgatgaccc
    63061 tacatgtaga aattacttag cactatattg ttgtgttcac ggagtaagaa aaaatggaga
    63121 acttatattt ccaacatgtg aaaaaatgtt aatagagttt aatgttgata aaaatagaaa
    63181 aaagaaaaag aaaggttcaa aggtaaagtt gattaatgcc aaaactggtg aagaaaaaat
    63241 atttgattct atagatagtg cagcatgttt tttaagacta cagagtcagg cagtttacca
    63301 aacaattaaa aagaaaacta aaacaagaag tggctggaaa gctgaatata ttgaggagga
    63361 ataatggaag tttcaaggac tgaatacaca attaaaagag caaaagagtt atatgataat
    63421 ggagaggata tatttattgc tatagataag gctagagaag aatatgagga gatggttaaa
    63481 agtgaatatc ttagctagtg tgatattagt aataggaagt tttatagctg gtagagttta
    63541 tgagtataga ttgaatttaa atgaaaatga tgaagctgat tcaaaagtac ttttagatgt
    63601 ttttaatgaa attagtgtgt taagagaaga aaataaaagc cttaaagaaa agttacaaga
    63661 gaaagagtta ctattcatca atagattaat agatttttta catgataaaa agatatgcga
    63721 atgttgtatt tatgactgta agattgatga tattgaatat gattgtgaag atggtattaa
    63781 aaagtggctt gatagcgaag aacttatatt tgaatagaag aaatatctaa ttaaaacagt
    63841 ttagagagtt gcaaaatgtt ttttaataaa attatcattg agatgttttg taactctcaa
    63901 aaatgaaaat aaggaggcgt tgtattgctt acatttttag atttattcgc agggataggt
    63961 ggctttaggc tagggatgga aaaagcagga cataaatgtt tgggacattg cgaatatgat
    64021 aaattcgcaa atttaagtta taatgccatg cacaaaccga aggaggatga atggtttgaa
    64081 agagatatta gagaaattag aacagaaaat atcccaagag cagatgtctg gtgttttgga
    64141 ttcccatgtc aagacatttc tgttgcaggg aaacaatttg gattcagagg agaacgttca
    64201 agtttatttt ttacagttac aaaacttatt agagaactca aagaagaaga tagacccaag
    64261 tatttactta ttgaaaacgt taaaaatcta cttagtgtta atggaggatt tgatttcctc
    64321 aaagttctcg ttgaactgga tgaaatcggc tatgatgcag agtggcaagt tcttaattct
    64381 aaaaacttcg gagtacccca aaatagagaa cgaatattca ttgttggaca ttttagagga
    64441 cgaagtacac gaaaagtatt tcctatcgaa agaaaaagta gaaaaaatct tgagcaacta
    64501 aataatccaa ctcatagtac aaatagaatt tatgatgcag ttggaattgc tagatgtatt
    64561 agaagtcagg caggaggtgg aggtgctaaa acaggtctat actttataga cttaaataaa
    64621 aactctaaag taacaataaa tgctagatgc cttaaagcaa aatataatgc aggtgtgaca
    64681 aatagaaatt gtgataatag tggagtttta gttaatgcag ttttaacgcc cgatagggta
    64741 aataaaagac aaaatggtcg tagaattaaa gaaagcggag aaacaatgtt cacattgaca
    64801 gctcaagata aacatggaat tttgaaaaat ggagatataa gaaggttaac accaaaggaa
    64861 tgctttaggt tgcaaggatt tccggataaa tattacgaaa gagcagcaag tgtatgctca
    64921 gatagtcaac tgtacaagca agcaggaaat gctgttactg caaatgttgt atatgaaata
    64981 gcaaaaagaa tgggctaaaa gttgcaaaat gtcttttagt atgaatattt ttgaagtgtt
    65041 ttgtaactct caaaaatgaa aataaggggt gggataaatg tatgaatata tattaagatg
    65101 gcaaatagga ttatcgttag aaaatagaaa aatacattat acatatggaa gtaaagaagc
    65161 tttaagaaag aaagcaaagg cattggctaa agatgaaaat atagtactaa taactataga
    65221 taaggtagat gaagttataa aaaatactat aagcgagaag attatagaac gttttgaaaa
    65281 tttataaggg gtggaattat gataatacac aaatttataa tacatgtttt agataagaat
    65341 agtgatacac caatattgaa tgattttgaa ggtagggtta atcaagatat ggtcctattt
    65401 tttcaaaaga aaataagcaa agtatcaaga gataatgaca tcagaacagc agtatttaat
    65461 aactatagta acaatctaat taagaagtgt tgtgaacaaa ttatttatga tgaaagttca
    65521 tttttaaata actctaaaga gattgcagct tatttatttg atgttatgaa attgaatgct
    65581 acattagaat cttgcgactt agcaatttgt ttatactctc aaaaagatga aaagaaagtt
    65641 gctatattaa agcttgatta caataattcg tatactcatt caattgagtt taaagatgat
    65701 aaatttaata tacagatgtc taaaaatgaa attaatatac aagagactaa gacggttaaa
    65761 attgctgctt tggttggatt gagtggaatg aatgacaaat atcatcttag ggttttagac
    65821 aaggatgcag agaaggaaga agctaattct aagtttgtta cagagttctt aaatgccact
    65881 aagataaaag atgataagta taagactaag aagttcaaaa atacagctga gaattggata
    65941 actaatgctc ttagtaatga tataaaacaa gcagaggatg taagaagtat attaaattat
    66001 actttgagag aaaagcatga aattgatata aatgattttg ttgataaaac aattaaagat
    66061 gataagttaa aagatagttt taaagaacat atggaagaaa aaggtcttgt tgaaggattt
    66121 agtatagata aaaaatgggt tgataaaaag cttaaaaaga gaaatataaa aactgacaat
    66181 ggctttgaaa taaaaggtaa cttaactgat tttgaggacc caatgaaata tacagtaaga
    66241 caaaatcaaa atgggtctat agatatagtt attaagaatg taacatttta tgaggaaaag
    66301 taggtactca tgtgactatt ggctagagaa ggagaagtaa ataataagag gatgtaaatt
    66361 taaactagtt aggaggaata acttatgaag atttttttat tgactatact gctaataatt
    66421 atttgtatat tagcaaatta tgtgaaaaat cgcatatata aaaaatctat aaataatcta
    66481 aaatataaat attctgtagg ggaaaagatt atatatcatc aaataaactg ttactataac
    66541 agaatggttg gttgtgaaat tttagaaaaa tgttatagta cgaaatttag aaaaagaaat
    66601 accccgcttt ataaagtaaa agcatatgta ggtgataacg atacaacatg ggttatacca
    66661 gagtggagaa ttgaatgtct tgctacgact tatggagaat ttcctaaata ttaaataata
    66721 aaaattggct ggagaaggag attgtaaatt atgtttaaca tctataaagt gaaaataaag
    66781 actaaaagaa cattggagca ggtaagaaat caaagcgtag actttgagta ttcagaaaaa
    66841 ggattaaaaa atactctgaa atactataac ttgattgatg atttaaaagt aatagtagtt
    66901 aaatttggag atgaatattg tctagctaat tacaatgaag aagatagaaa aataataatg
    66961 gaagcacatt atcttttaga gcaggatgaa tatactggat gttatataaa tgaatatgaa
    67021 cgatttaaaa aagattggga aaatggtaat tgtgatgggg aagcctgtat ggtattttca
    67081 gatgatgaaa ttgagataat tgagaagcta agggagggtt aaatatgaat aaaagaatta
    67141 aaatgaaaaa aagattaatt cataaaaagt gtgatgaaag atgtgtcaac tatgactttg
    67201 taattagcaa taaccttata acttgtaatg tgtgtatagg atgcaaatac aaagaaaata
    67261 tggataaagt atgtgaagag aactataaga aattaagaag taaatagaat aaaatagtca
    67321 aggtaagttt gtgaatgaaa ctagaatgtt atagacttac tttgacttat aaaaggagtg
    67381 tgttaaatgg ctaatatata ttgtgaaaat tataattgta aaaactactt tgaagatatg
    67441 tgtatgcttg aaagaattga aattaataac ttcaaagaat gcgaaagcta tcttgaaggt
    67501 aaaaatgagc tatatgaatt agaaaatgga tatactatac atcctaaaga tttgaaaatg
    67561 gtgaaaagta aagattattc tgttgaagtt actcatattc caactggtat tacagtaaaa
    67621 tgccgttcta caaatagtat tttaaaaaat aaaaataagt gtttggaagc tctagaagaa
    67681 gaactaacaa aaataaactc tcacttagag ctagaagatt tacgctaaat aggaagtgag
    67741 cttatgaaac gaagaagatg cagttggtgt ggtaagttat tttatcttga agaaaaatct
    67801 aaggatgttt attgttgtaa agaatgtagg aagaaggcta agaaggtgaa aaaatgaaag
    67861 tttttcttgt aatagatgga gaaccagttg gtaaagaaag acctagattt aacttggcta
    67921 ctaaaaggac ctatacacca cagaaaacta aggactatga agaattaata aaatggttat
    67981 atcaatctaa agttagacat tattttactg gatacataaa aatgacttta agatgttatt
    68041 actctatagc aaaaagtaac agtaaaaaga ttaaagagca gaaaagaaat aatgtgttaa
    68101 gacccaataa aaaaccagat attgataatg tggtcaagat tatagctgat tcactcaatg
    68161 agatagctta taaagatgat acgcagattg ttgaggttgt agctagtaaa tattacagtg
    68221 ataaaccaag agttgaggtt atattagaag atgttattta accaacggaa aaatccgttc
    68281 gttagattag gtactcagtt tttcataaaa atgtgaaaaa gctgaataga gaatatatca
    68341 aatggtaaag gagagataaa ttatgaatga aaatataaat aaagaaataa cagtacttgg
    68401 aactttagaa atcgagggaa tgaaatttca taacattgag ggtggatttg gagaacataa
    68461 gaaagcaatg ctagtaaaag atatagctga gatacataat agagaatcta gacagattaa
    68521 tgagcttata aataagaata gaaaaagatt taaagatgga aaagatatat tagatttgtt
    68581 aggtgtcggt ttggacgata ccaaaataaa agaattagga tttactcaac aatcaattaa
    68641 ttcttataga gggttaaaaa acaaagggtt attatctggg atttatatat tatctgaaag
    68701 aggttatgca aaattattaa aaatattaga agatgatata gcttgggaat tatatgagaa
    68761 gttagttgat ggatatttct ctatgagaaa agaactaaat aatcctcttt taagtgcatc
    68821 aaaggagtta caagctatat ttatgctaga taagaaacaa gaagtcttag aaactaaaat
    68881 agagaatgtt aatgagaagt tagagaactt tatggatgat gcaccattat tcaatatcga
    68941 gtgtgagtgt attgttaaag aggttaagag agtagcaaca aaatcacttg gtggacatgg
    69001 aagtaaggct tataaaaata aatctttaag aggtaaagtt tatagtgata tataccatca
    69061 gattaaacga gaatttggag tagatagtta taaggctata aagcgttgtc aattagataa
    69121 agtattagag attgtaaata gttataagtt acctatagtg tttgaagaag aaataagact
    69181 tttgaatagt caattatcaa ttgtgagtta agacaggaat agatttttct cctttaaagg
    69241 ggaaaacctg caatagttaa ttaaaagaga aaaggagtgc tttcacactc cacttgtcaa
    69301 aaatataaag cttttatcca agattattat aacataaaca ggagtgtgaa agtatggata
    69361 ataatattaa taaaaaagaa ctatttaaaa aagtagaagg tagactacat cattataaat
    69421 ttttaagtgc agaaattaaa aatcttgaat tagatataga aagtagagaa aatgaaatat
    69481 ttggttgtaa ggctatcggg tatggtgaaa aagtaagtcc aacatatgct tttaattcaa
    69541 ctgttgagaa tgagattata aaaaaagaaa gagatattgc tagattaaaa aaactgaaaa
    69601 aagataaaga aatagaaaag aagaaaatag aaaatgcact tacatgctta gatataagag
    69661 aagaacattt ttttaaactg ttttataata gcagaatgaa aaatagtatg gtttatatat
    69721 ccttagaaat gaactcagat aggaaaacat gtagatgtgt aagggaaaga ttagtgtata
    69781 aagttatgga tatgctttat ccaagaatta aggaaaatga actcccatta tttaaaaatt
    69841 agaaaattcc ccagtttttc cccagaaatt cccactttat tccctacttt ctccccgttt
    69901 tgattaaaaa agcatgagat aatagtattg tggaaataaa gatttccctc tcaaaactta
    69961 atatttgact agggttaagg gattgcccta gtcactatga acagactagg cagggcatga
    70021 ggatgctgtt agttcaattc taactatgtt caatctttag tttttctatt tcaattaatc
    70081 tacggataca ctaaaaaata gtatatgaat tgagattaaa atctcataca attttgtatc
    70141 ttaattcaaa gactaaaaac cgagtggggc ttggtaacct cactcaccat gcaagtactg
    70201 gtttaatcta ggttcgattc ctggaacttg ctccctttaa taatatgtat cccccattaa
    70261 aaaggcttag attaacttct aggtcttttt taatacaaaa atttattaaa aatgcacggc
    70321 atgcactatt cagatatgca tgtcatgcat gtctaaagtc gaatatttaa tattttcgat
    70381 ggctcaaatt gaggggtcga aaataaaaac aggaggtagt agtatgttga aaattttaca
    70441 agagaaaaat gtaaaagtaa tgtggtccaa aaatggagaa gaagtttggt ttaatgcaaa
    70501 tgacgtagga gaggaactag gcatagtaaa tattcgtgat acattaagaa atatagatag
    70561 agaatataaa aagaaattta atgagtctac tgtcggagat tcctacacta gaaactttaa
    70621 agataaattg cctaacttcg gtactacttt tgttacagaa gaagctgtgt acaatatgtc
    70681 atttagaagt aataaaccag aagcaaagtt atttacaaaa tgggttacaa aaacacttaa
    70741 acaaattaga atacatggtt attatattgc tacagaaaaa gaccaggaat ggctggatat
    70801 aaggacagaa ggcaaaaaag taagaaaaga ttttacagat gaaatacaag agtttgtata
    70861 ttatgctact agtcaaggta gcaataaacc tcagatgtat tataaacatt ttactgaact
    70921 tgtaagaaaa aaattaggta ttccaaaagg tgtgaaaaga gatgagttaa atcaaagcga
    70981 actatttgat atacaagcac ttgaaagaat tatatctatg aaattaccta agttaataga
    71041 taaagatatg aattataaag aggtatataa aaagattaag gaattaatag aaatgattta
    71101 agggactgtc ttgatggagg gtctttttta attcccaaaa cgacaaacaa acgaggtggt
    71161 gatgtgcaag atgtcaaaga aaaggtaaaa caagattaca taaaaggtat gaaacaaaag
    71221 gaaatatcag caaagtatga cattagttta aacactttaa agtcatggat aaaaagatac
    71281 aattgggcta gtgagaaaaa gaagggtgca cctaaaaata aaagaggtgc acccataggt
    71341 aataaaaatg ccactggtcc tcctggaaat aaaaatgctg aaaagtttgg tttcttctca
    71401 aaatatctac ctgaagaaac tagggaatta atacaagaaa tatctataaa agataaattt
    71461 gatattcttt gggaacagat aacaattcaa tatgcagcaa taataagagc acaaaagata
    71521 atgtatgtta aagacaagga agaaatgatt aaggagttaa agaaacatga aagcacagaa
    71581 aatggtgaga agatagagta tgaatttcaa tttgcatggg ataggcaagc atcttttctt
    71641 aatgcacaga gtagagctat gagtgaactt agaagtttaa ttaaacagta tgatgaaatg
    71701 attcataagg attggaattt ggctacagag gagcagaaaa caagagttga gaagttgaaa
    71761 tgtgaagttg ataacctaag taaagatgat attggagatg atgagttgaa aataagtgta
    71821 gattatggtg atagaaatga tagttagagt aaattttaat ccagatttca aggaagc
//
LOCUS       DAEPHU010000009        71585 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 01A10CD0081
            SAMN05941466-rid12468953.denovo.009, whole genome shotgun sequence.
ACCESSION   DAEPHU010000009 DAEPHU010000000
VERSION     DAEPHU010000009.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941466
            Sequence Read Archive: SRR6291087
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 71585)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 71585)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068158.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 22:43:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,892
            CDSs (total)                      :: 3,805
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 87
            rRNAs                             :: 8, 1, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 55
            CDSs (without protein)            :: 55
            Pseudo Genes (ambiguous residues) :: 0 of 55
            Pseudo Genes (frameshifted)       :: 21 of 55
            Pseudo Genes (incomplete)         :: 28 of 55
            Pseudo Genes (internal stop)      :: 16 of 55
            Pseudo Genes (multiple problems)  :: 8 of 55
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..71585
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941466-rid12468953.denovo.009"
                     /strain="01A10CD0081"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            complement(121..894)
                     /locus_tag="KR231_000644"
     CDS             complement(121..894)
                     /locus_tag="KR231_000644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SigB/SigF/SigG family RNA polymerase sigma
                     factor"
                     /protein_id="HBH0003055.1"
                     /translation="MKNVANATHYLNMDTKELFNLYNKNKNVDIRNILIERHLYLARL
                     LAKKYINKGVDFEDIYQVASLALIYAIDRYDVEKGFEFSSFATPTIVGEIKKYFRDKV
                     WTLRVPRRIQELSKKISDAKIKLEQENKKHPKVKDIADYIGVSEEDVLEAMEASYGYQ
                     PMSLDSSSNDDSEDKDITLIDKIGKEEGNFGSIEYEDFINKFIETLNELEVKIFKDRF
                     FFDKTQSSIAKELGISQMTVSRLEKKVVEKLKKEYEKNL"
     gene            complement(894..1280)
                     /locus_tag="KR231_000645"
     CDS             complement(894..1280)
                     /locus_tag="KR231_000645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HBH0003056.1"
                     /translation="MEITTNPDYVSIIRLTASGIANKMGFPIDDIEDIKVAVSEACTN
                     AIKHSKDDVFNIVFNILDNAINIEIQDNGKGYDVSSISTPDLENPKESGLGLFIIKTL
                     MDDVDIESEHNQGTKIKMTKYLGVDI"
     gene            complement(1305..1622)
                     /locus_tag="KR231_000646"
     CDS             complement(1305..1622)
                     /locus_tag="KR231_000646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="STAS domain-containing protein"
                     /protein_id="HBH0003057.1"
                     /translation="MSMNIDSNLDSQNKFWNVCLDGELDVSTADKLKEHLHALIEKNM
                     LDVKINLKDLDYIDSTGLGAMIGVLKKLKINEKEIYIVNPKSNVRKIFTITGLDKIFK
                     VEG"
     gene            complement(1634..1894)
                     /locus_tag="KR231_000647"
     CDS             complement(1634..1894)
                     /locus_tag="KR231_000647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF948 domain-containing protein"
                     /protein_id="HBH0003058.1"
                     /translation="MNAWGWQIGAVLVGSSALIVAIYLAKTLNSINKVVEKAYKIVDY
                     NERHIQDIVENASSISKGIDDIVYVINKILSIGNIFKIIKRK"
     gene            complement(1894..2190)
                     /locus_tag="KR231_000648"
     CDS             complement(1894..2190)
                     /locus_tag="KR231_000648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HBH0003059.1"
                     /translation="MCNKRSCKKGGFLLLGAILGFIFGMFFAPKKGSELRKETKEKFN
                     DVKENPKEVLHETFNDVKERIINLVDDDNNEEDIKISEEDIVISKSFDDEGDVN"
     gene            complement(2259..4685)
                     /gene="gyrA"
                     /locus_tag="KR231_000649"
     CDS             complement(2259..4685)
                     /gene="gyrA"
                     /locus_tag="KR231_000649"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA gyrase subunit A"
                     /protein_id="HBH0003060.1"
                     /translation="MEENNKILPIEIAEEMKKSYIDYSMSVIAGRALPDVRDGLKPVH
                     RRILYSMSELNLTPDKPYRKSARIVGDVLGKYHPHGDTAVYYAMVRMAQDFSTRALLV
                     DGHGNFGSVDGDSPAAMRYTEAKMSKLSLELLRDIEKETVDFKPNFDESLKEPSVLPA
                     RYPNLLVNGSNGIAVGMATSIPPHNLAEVIDATVYLIDNPECSVDDLIKFVQGPDFPT
                     AAIIMGKESIAEAYRTGRGKVKVRSRAFIEELPKGKQQIIVTEIPYQVNKAKLVERIA
                     ELVKEKRIEGISDLRDESNRNGMRIVIELKRDANANIVLNNLYKHSQMEDTFSIIMLA
                     LVDGQPRVLNLKQILYHYIKHQEDVVTRRTKFELNKAEARAHILEGLKIALDNIDAVI
                     SLIRASKTGQEAKLGLIEKFKLTEIQAQAILDMRLQRLTGLERDKIEAEYEDLIKKIN
                     RLKEILADERLLLNVIKDEITIIKENYSDERRTEIRHAEGEIDMRDLISDEEIAITLT
                     HFGYIKRLPSDTYKSQKRGGRGISALTTREEDFVRHLVTTTTHSRLLFFTNKGRVFKL
                     NAYEIPEGKRQAKGTAIVNLLQLSADEKIATLIPIDGNDENEYLLLATKKGIVKKTKR
                     EEFKNINKSGLIAIGLRDDDELIGVELTDGKQEVLLVTKEGMSIRFDENDIRYMGRTA
                     MGVKGITLSKEDFVVSMNLCSKGTDVLVVSKNGFGKRTNIEEYRSQIRAGKGIKTYNI
                     SEKTGTIVGADMVNEDDEIMIINSDGVLIRIRVNEISLFGRVTSGVKLMKTNDEVNVV
                     SIAKINIEEE"
     gene            complement(4705..6606)
                     /gene="gyrB"
                     /locus_tag="KR231_000650"
     CDS             complement(4705..6606)
                     /gene="gyrB"
                     /locus_tag="KR231_000650"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003226808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase (ATP-hydrolyzing) subunit B"
                     /protein_id="HBH0003061.1"
                     /translation="MKQEYGASQIQVLEGLEAVRKRPGMYIGSTSPRGLHHLVYEVVD
                     NSIDEALQGYCSDIYVSINEDGSVLVKDNGRGIPVEIHPKTGKSTLETVLTNLHAGGK
                     FGGGGYKVSGGLHGVGVSVVNALSKWMVAEVYLNGKRYKQTYEKGLPTSKLEVVGESQ
                     DKGTMIQFMPDETIFDEIEFKYETLEYRLRELSFLNKGIKIVFEDKREGQEKRKEFHY
                     TGGLVEYIKYLNKSRTGIHDDIVYIDKKVDDCFVELAMQYTDGYTENIYSFANNINTH
                     EGGSHLSGFKAALTKTVNDYAKRNKFLKENDVNLLGEDIREGLTAVVSVKLPEPQFEG
                     QTKTKLGNSFMRGIVDSVTVDELGSFLEENPSTARIIVDKALRAQRAREAAKKARELT
                     RRKSVLESTSLPGKLADCAEKDPSKSEIFLVEGDSAGGSAKQGRDRNSQAILPLRGKI
                     LNVEKSRLDRILSSDEIKNMITAYGCGIGEDFDIDKARYHKIIIMTDADVDGAHIRTL
                     LLTFFFRYMRPLIDEGYVYAAQPPLYKVTKQKKEHYVYSDKELNILLDEIGRNGVELQ
                     RYKGLGEMNAEQLWETTMNPETRTLLQVTVEDAAIADEVFSMLMGDKVAPRKEFIEEN
                     ARFVRNLDI"
     gene            complement(6607..7722)
                     /gene="recF"
                     /locus_tag="KR231_000651"
     CDS             complement(6607..7722)
                     /gene="recF"
                     /locus_tag="KR231_000651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication/repair protein RecF"
                     /protein_id="HBH0003062.1"
                     /translation="MKLKSLQLVNFRNYKKLHLEFNGKVNLLVGKNGQGKTNIVESIY
                     MLSFGKSFRTNKDKEMVRFNSENLYIGGSFSKYNKYSLIELIIGKDKKGIRINKVPLQ
                     KIQELLGNLNVVIFSPEDLRLVKEGPKERRAFIDKEISQIIPKYYKYLTNYNKTLSQR
                     SRVLKNIHVDEALLDVYDDTLAKYGSYIYILRRDFIKKIANISENMHMNLTNGVERLS
                     IRYKNQINITDEDTIDTVYNKFLAKLSSNRPNDIESKTTRYGIHKDDLNIFINDLDAR
                     LFGSQGQQRTASISLKLSEIELIKNEVEEYPVLILDDVFSELDEARQKLLVNNLSNVQ
                     MFITSAEVSHKKIFDEKNVTIFNIENGDVISIENGGN"
     gene            complement(7739..7945)
                     /gene="yaaA"
                     /locus_tag="KR231_000652"
     CDS             complement(7739..7945)
                     /gene="yaaA"
                     /locus_tag="KR231_000652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S4 domain-containing protein YaaA"
                     /protein_id="HBH0003063.1"
                     /translation="MTEITIESEYIKLDQFLKLAEIASTGGHAKFLIQEGLVTVNDEI
                     ELRRGKKIKSGDIVEIEGTKIKVL"
     gene            complement(8082..9188)
                     /locus_tag="KR231_000653"
     CDS             complement(8082..9188)
                     /locus_tag="KR231_000653"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420481.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit beta"
                     /protein_id="HBH0003064.1"
                     /translation="MKIICNQKILANRIGIAQKAINGKTTIELLKGILISTEEGQLKL
                     TGYDAEIGIETYVQAEIIEKGDVVVDARLFGDIIRKLPDSFVEIETDSENNIYINCVN
                     SRFKIKGYAAKEFPKLPELNEEDLYSIPQEILKNMIKQTVFAISQDQTKPVLMGELLE
                     IVDRNLNLVAIDGYRLAVKSCSVDSLTENIKVIIPGKTLIDVNSLLSGEDNVKVGFNE
                     KNAIFIINDTKIITRLLEGDFIDYKKLLPREHNSRVKLNTKELLNSIERASLLSQSEK
                     NNLIKLSIRDKVMAITSNTEKGNVYEEVEIDLDGDYLDIAFNSRYFIEGLKNIDNEEI
                     FIEFTTNVNPCIIKPTDDVNYIYLLLPVRISSNI"
     gene            complement(9430..10752)
                     /gene="dnaA"
                     /locus_tag="KR231_000654"
     CDS             complement(9430..10752)
                     /gene="dnaA"
                     /locus_tag="KR231_000654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000428021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosomal replication initiator protein DnaA"
                     /protein_id="HBH0003065.1"
                     /translation="MMDIVSLWDKTLQLIKGDLTSVSFNTFFKNIVPLKIHLNDLILL
                     APSDFNKDILENRYLHLIEDAISQLSLKKYNIKFVLSEKEVADLNSDSTDLNYRVLYP
                     NLNPKYTFDTFVIGNSNRFAHAACVAVAESPAKAYNPLFLYGGVGLGKTHLMHAIGHH
                     IVSQKKDSKVVYVSSEKFTNELINSIKDDKNEEFRNKYRNVDVLLIDDIQFIAGKERT
                     QEEFFHTFNTLHEANKQIIISSDRPPKDIPTLEDRLRSRFEMGLITDIQAPDFETRIA
                     ILRKKAQLERIDVPNEVMSYIAKNIKSNIRELEGALTRVVAYSSLSNRVISFDLATEA
                     LKDIITTSKNEEINVLRIKEKVSSVFNLKMEDFNSKKRTRSIAYPRQIAMYLTRELTD
                     LSLPKIGEEFGGRDHTTVIHAHDKVSKDIEESEEIKTKIDKIISDLKG"
     gene            11408..11545
                     /gene="rpmH"
                     /locus_tag="KR231_000655"
     CDS             11408..11545
                     /gene="rpmH"
                     /locus_tag="KR231_000655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L34"
                     /protein_id="HBH0003066.1"
                     /translation="MSKRTYQPKKRQRSKEHGFRKRMKTSNGRNVLKRRRAKGRNRLT
                     H"
     gene            11623..11967
                     /gene="rnpA"
                     /locus_tag="KR231_000656"
     CDS             11623..11967
                     /gene="rnpA"
                     /locus_tag="KR231_000656"
                     /EC_number="3.1.26.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420486.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease P protein component"
                     /protein_id="HBH0003067.1"
                     /translation="MDFNRTKGLKKDSDFRKVYKHGKSFANKYLVIYILKNKSDYSRV
                     GISVSKKVGKAITRNRVRRLIKEAYRLNIDEKIKPGYDIVFIARVSSKDATFKDIDKS
                     IKNLVKRTDISI"
     gene            11999..12250
                     /gene="yidD"
                     /locus_tag="KR231_000657"
     CDS             11999..12250
                     /gene="yidD"
                     /locus_tag="KR231_000657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertion efficiency factor
                     YidD"
                     /protein_id="HBH0003068.1"
                     /translation="MNKIIYILKEISKHLSNLCIYLVRFYQKYISPLKGPTCRFYPTC
                     SQYSIEAFKKYGFVKGMYLTIRRLLKCHPFHPGGYDPLK"
     gene            12282..12989
                     /locus_tag="KR231_000658"
     CDS             12282..12989
                     /locus_tag="KR231_000658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HBH0003069.1"
                     /translation="MNIIGNFLGLILKVIFEFVNHYGISIILFTILVKIILLPLTIKQ
                     TKSTKAMQDIQPRIKEIQEKYKNKPEKQNEEIVKLYGEAKINPLSGCLPLLIQFPILI
                     GLFSVLREPVAHGVFANKAAFLAADNGFLWIKSLTSPDYVLAVFSGASAYVMQKVMTP
                     KDQLQGSMKVMTYVMAGMSFYWGFIFPAGLTLYWTVSNLFSIAQYYLIMNPLKAKLAA
                     NSKEEKVNEKKPKINKK"
     gene            12958..13587
                     /locus_tag="KR231_000659"
     CDS             12958..13587
                     /locus_tag="KR231_000659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein jag"
                     /protein_id="HBH0003070.1"
                     /translation="MRKSLKLIKSKSKEEAISKAIAELNLKAEDIEVEILENPSKGFL
                     GFIGAKDGTYEIFVIEREVDVAKNFIEVMLKNANVDAKVNVSQKDNLIMVDIEGKEAA
                     SLIGRRGETLDSIQFLTGLALNKINKDSHTRVLVDIENYRSKREESLIRYANKVAREV
                     AKTRKTKKLDYMNPYERRIIHSALQNDKYVITYSEGTDPYRRLVIECKR"
     gene            13699..15078
                     /gene="mnmE"
                     /locus_tag="KR231_000660"
     CDS             13699..15078
                     /gene="mnmE"
                     /locus_tag="KR231_000660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis GTPase MnmE"
                     /protein_id="HBH0003071.1"
                     /translation="MFIDDTIAAIATAPGEGGIGILRISGEKALKVAEEIFKSMSGKS
                     IEEYNKRTLIYGNIVDNENVIDEVLLAYMKGPNSYTGEDVIEINCHGGFISVKKILEL
                     ILSKDVRLAEAGEFTKRAFLNGRIDLSQAEAVIDVIKAKTDIAHEVAQNQLEGSLSKK
                     IRELRDKVTEILAHVEVAIDYPEEDIEHITYQTLKEKTDELKKDIKKLYDTAESGKIL
                     REGLKTVIVGKPNVGKSSLLNSILGENRAIVTDIPGTTRDVIEEFVNIKGIPLKIVDT
                     AGIRDTDDIVEKIGVEKSKESFTSADLIVMVLDASRKLSEEDIEILEKLKDKQTIVLL
                     NKNDLKQEIEEEKILKYVENNSIIKISALQQEGIEELQDKIESMVYKGSIKNNSSLVV
                     TNSRHKDALSKAYKSATDALIALEQSMPFDFVEVDLKNIWDYLGYINGDTVTEDLLDN
                     IFHNFCIGK"
     gene            15176..17068
                     /gene="mnmG"
                     /locus_tag="KR231_000661"
     CDS             15176..17068
                     /gene="mnmG"
                     /locus_tag="KR231_000661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012065747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis enzyme MnmG"
                     /protein_id="HBH0003072.1"
                     /translation="MKFEAGKYDVIVVGAGHAGCEAALATARMGYKTLIITMSLDSIA
                     LMPCNPSIGGTGKGQLVKEIDALGGQMGLNIDKTYIQSRMLNTAKGPAVHSLRAQADK
                     FKYHEEMKKTLEDEPNLDIAMDEVVEILHEGNVVIGVGTKLGCSFKSKAVILATGVYL
                     NSKIYMGEVAFYEGPNALGYAKYLTDSLVELGLRMRRFKTGTPARVHRDSIDFSVMSL
                     QEGDEKVTPFSFMNENIEKKQEPCYLTRTTEETQKVILDNLKRSAMYSGVIESTGPRY
                     CPSIEDKVVRFSDKTSHQLFIEPEGLNTKEMYIQGISTSLPFEVQLDMYKTIKGLENC
                     KIMRPAYAIEYDCVDPTQLKISLEIKGVENLFSAGQFNGTSGYEEAAAQGLMAGINAV
                     RKIEGKEPFVLDRSEAYIGVLLDDLVTKGTNEPYRMMTSRAEYRLYLRQDNADMRLTQ
                     KGYDIGLVKKDRYERFLNKKAAVEKEFERLKNERVTPKEVNSLLEEKGATPIKVGISL
                     YEFLKRPEVTYELLEELGKGAGEDVSREVKEQCVIITKYEGYIEKQLKQIDQFKKLEN
                     KKLDEKINYSSIEGLRLEARQKLDDIKPISIGQASRISGVSPADISVLLIYLEQIRRT
                     RGGKGE"
     gene            17061..17780
                     /gene="rsmG"
                     /locus_tag="KR231_000662"
     CDS             17061..17780
                     /gene="rsmG"
                     /locus_tag="KR231_000662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(527)-N(7))-methyltransferase
                     RsmG"
                     /protein_id="HBH0003073.1"
                     /translation="MNNIELLKNGIEGFNIDTNDSMLEKFKIYREILVEWNKKMNLTG
                     IEDEKEVYIKHFLDSISAVKNGYIKNGMSIIDVGTGAGFPGIPLKICLDSLELTLLDS
                     LNKRINFLEEVSRVLELDNITFIHGRAEDFGKNEDYREKYDVATARAVAGLPILMEFC
                     VPFVKVGGYFICLKGPNANLELEESQKAIDVLGLEYIEKIDVELPEVDLNHNILVFKK
                     VMETPVKYPRKAGKPAKNPIK"
     gene            17943..18728
                     /gene="noc"
                     /locus_tag="KR231_000663"
     CDS             17943..18728
                     /gene="noc"
                     /locus_tag="KR231_000663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoid occlusion protein"
                     /protein_id="HBH0003074.1"
                     /translation="MEDKRVMEIPIEDVVPNPYQPRKIFSQVSLEELSNSIKVYGIIQ
                     PITVRAKDGKYELIAGERRLRAAKLAELKTIPAIINNMNDESSAVLALLENLQREDLN
                     FIEEAIGYENLIKEHAFTQQQLAEKLGKNQSTVANKLRILKLPNDIKMKLIENNLTER
                     HARAFLKLPSEDLMQSVLDKVIKNELTVKKTEKLIQDVLEETKVQEEPDKKQNIKGAM
                     SIRIYINTIKQAFDAISNTGIDAKYNEIDKGDYMEVVVKIPKK"
     gene            18863..19636
                     /locus_tag="KR231_000664"
     CDS             18863..19636
                     /locus_tag="KR231_000664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="HBH0003075.1"
                     /translation="MGKVIAVFNQKGGVGKTTTNVNLSASLGTLGKKILVLDLDPQGN
                     TTSGYGINKNEVENTIYEIMLDGLHIKEAIISTEFENVDVVPSATELSGAEIELTSKT
                     NREYILKNSIKAVIDEYDYIFLDCPPSLGMLTINCLTAVDSVLIPIQCEYYALEGVSQ
                     LMETIKLVKSRLNADIEIQGVVLSMFDGRANLSIQVVEEVKKYFKGSVYTTLIPRNVR
                     LAEAPSHGKPVIYYDKRCRGSVAYLELAEEFIDLEEEEW"
     gene            19638..20501
                     /locus_tag="KR231_000665"
     CDS             19638..20501
                     /locus_tag="KR231_000665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParB/RepB/Spo0J family partition protein"
                     /protein_id="HBH0003076.1"
                     /translation="MENKSKRSNRLGRGLSALIPEIKGETSEKEIVNIDIDKIYPNEV
                     QPRKQFDEEKIKVLSDSIKNYGVLQPIVVKMDENNKYMIIAGERRFRASKLANKNQIP
                     AIIKDIDMKDIMEIALIENLQREDLNSIEEALAYKSLIEHYNVTQEEISEAVGKSRPH
                     ITNTLRLLNLGQDVIEMIDSGRITAGHGKALLRIADKDLQLQIAKKIEEEELSVREVE
                     NIAKKISENKQEEPKKSKPKDVFILDVEDKLRNIFGTKVNISKGKKKGKIEIEYYNDD
                     DLNSIVSMLLE"
     gene            20534..21676
                     /locus_tag="KR231_000666"
     CDS             20534..21676
                     /locus_tag="KR231_000666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class V-fold PLP-dependent
                     enzyme"
                     /protein_id="HBH0003077.1"
                     /translation="MIYLDNAATTYPKPERVYNAVLDCMKNYCANPGRAGHKLAMRAA
                     REIYDTRENIAKLFNVSNPMNIVFTSNATDSLNLAIKGVLQEGDHVITTSMEHNSVIR
                     PIKALEKRGIENTVVKCDYEGFLDYEDLEKSIKNNTKLIVTTHASNVCGTLIDIKKVG
                     EIAKKHNILFLVDASQTAGVYDIDVNECNIDMLAMPGHKCLFGPQGTGILYVREGLNL
                     NILKEGGTGSKSEEIVQPELFPDKYESGTHNTPGIAGLNQGILFIFERGINNIRQHEE
                     ELCQYMIDKLEEVPDIKIYGPKDSKKRASVIALNIGDMDSGEVTFLLDSDYNIATRSG
                     IHCSPLAHTTLGTLKQGAVRFSIGYFNTKDEIDKAVEALKKISKNK"
     gene            complement(21810..22385)
                     /locus_tag="KR231_000667"
     CDS             complement(21810..22385)
                     /locus_tag="KR231_000667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GerMN domain-containing protein"
                     /protein_id="HBH0003078.1"
                     /translation="MKNKKIMLVLSILSISIFAVGCTNAQNGSDSSKKETKSNTNVEQ
                     PKEENNTEKEVPNNKAKPTPKEETKAQSATIYSFDVDKTDLIENKVDLNKIDENTLFE
                     ELQKLKVVPESAKLNSFTTKDIDGVKTGILDVSSDFTKSNLGSDAETLMLDSVARTYI
                     KNMNVEQIKITVDGSNYESGHIVLEEGDYLK"
     gene            22645..23937
                     /locus_tag="KR231_000668"
     CDS             22645..23937
                     /locus_tag="KR231_000668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HBH0003079.1"
                     /translation="MEILSLGEKIKKLRKEKNMTLKELAGDRITAAQISHIERDKSHT
                     SYELLEYLGDKLDVSVEYLLETKEMQSKKITDNLILQSEIYIKENELNKAEDQIKEVL
                     DICKRYDLMENYGRCNFLMANINLKKSNYNDAIENFEKALYFFIKNSDSENILKCYLN
                     IGKIYMQEDFYKGAISHFNFAEEILSESKFEDVNIHKELYSKMAYCYIKLDNPNMSLK
                     YIEKINEIDNRNDRKEDVDILVLKANNMLEIGKYEESRDYFKKALKILESEDNKTGLA
                     NVYLTICDVYRKIGETDRVLEYSQKVYDIKKNDEDEYMMSGLFKIIEAYIDKEDYDLA
                     RKYCKIALASSIKNKNKFNEYKALRFYANMYKNQNEVTLAIEYLIKCIKIVSDLGNNR
                     ILANLYIDLGQLYSNISKEKELEYYQKGVFMYKNLEIM"
     gene            24042..24644
                     /gene="yedF"
                     /locus_tag="KR231_000669"
     CDS             24042..24644
                     /gene="yedF"
                     /locus_tag="KR231_000669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfurtransferase-like selenium metabolism
                     protein YedF"
                     /protein_id="HBH0003080.1"
                     /translation="MSIKIDARGLACPKPVINTKRELDNLEEGVVVTIVDNETAKENI
                     LKLAKSLSCEANIVDEKENFISIEIRKGKNILDKQNVVDNKESELDNTCIFISSDKMG
                     LGNDELGKVLIKGFIYTLTESKPYPKYVLLVNGGVKLSAENEETIENLKILENMGVEV
                     LSCGTCLDYYNLKDKLQVGTVTNMYTIVETLKNASNTISI"
     gene            24717..24980
                     /locus_tag="KR231_000670"
     CDS             24717..24980
                     /locus_tag="KR231_000670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3343 domain-containing protein"
                     /protein_id="HBH0003081.1"
                     /translation="MNQMYIVSFNSTHHAIRSEKLFGENSLKVMALPTPREITASCGI
                     SIKFSFEDMEKIKTILVENNVDIKGIYCISKLENGSKEVEKLD"
     gene            24995..25180
                     /locus_tag="KR231_000671"
     CDS             24995..25180
                     /locus_tag="KR231_000671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF951 domain-containing protein"
                     /protein_id="HBH0003082.1"
                     /translation="MPMDLKIGDIVELKKQHACGCKEFEIIRTGMDIKIKCTKCSRLI
                     MLDRETLEKRVKKLIKK"
     gene            25283..26479
                     /locus_tag="KR231_000672"
     CDS             25283..26479
                     /locus_tag="KR231_000672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HBH0003083.1"
                     /translation="MAVKYAKRMQGLQGSEIRELLKLTQQPQIISFAGGMPAPELFPV
                     EEMKKVSVAVLEENGRSAMQYTTTEGYEPLREKIAARMNDKNKTNVNKDDILVTSGSQ
                     QGLDFAGKVFIDEGDVILCESPSYIGAINAFKSYQPKFIDVPTDSDGMIMEELEKILE
                     TTDRIKMIYVIPDFQNPTGRTWPLERRKKFMEIVNKFEIPVIEDNPYGDLRFEGETLP
                     SLKSMDTKGLVIFLGTFSKIFCPGYRLGWTCASPEILSKFNFAKQGADLQASTISQME
                     VSKFMDMYDLDAHVDKIKAVYVKRRDVMLKTMEEEFPEGLVFTHPEGGLFTWVELPSN
                     LNAKELMPKCLDKNVAYVAGGGFFPNGGRENTFRLNYSNMPEEKIIEGIKNIAAVLKE
                     AMGVEA"
     gene            26693..26971
                     /locus_tag="KR231_000673"
     CDS             26693..26971
                     /locus_tag="KR231_000673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S6"
                     /protein_id="HBH0003084.1"
                     /translation="MRNYELVYVVKPNSDEEVREAILNKVKEVVATDGEIVKVDTWGT
                     KKLAYPIAKFTEGFYVLVNFKSAVDVPKEIDRNLKINENVIRHMIVVA"
     gene            27008..27442
                     /gene="ssb"
                     /locus_tag="KR231_000674"
     CDS             27008..27442
                     /gene="ssb"
                     /locus_tag="KR231_000674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HBH0003085.1"
                     /translation="MNQVVLVGRLTRDPELRYIPGTGTPVASFTIAIDRDYVKKDGSK
                     ETDFIPVEVMGKSAEFCANYITKGRLVALQGSIRVDNYQTQSGEKRTFTKVSTRSVQA
                     LDSKNKSENSYRESAPAFEPSFEPQGLDPQGFQAIDDDDIPF"
     gene            27461..27688
                     /locus_tag="KR231_000675"
     CDS             27461..27688
                     /locus_tag="KR231_000675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S18"
                     /protein_id="HBH0003086.1"
                     /translation="MMNKKRRKKKRVCQFCADKNAKIDYKSTQRLQKYITERGKILPR
                     RISGTCAKHQRELTVAIKRARNIALLPYTLD"
     gene            27831..28151
                     /locus_tag="KR231_000676"
     CDS             27831..28151
                     /locus_tag="KR231_000676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MazG-like family protein"
                     /protein_id="HBH0003087.1"
                     /translation="MKIDKGSEITRNIKIIEWMKTEILMSVSDLFNLLFKGVKPLDEA
                     IQDTLANIIMITYLLAKRLGISFRDVDYKVKEKIKIGIDEDHSVERWYGDLSNLKKHM
                     DNRE"
     gene            28159..29115
                     /locus_tag="KR231_000677"
     CDS             28159..29115
                     /locus_tag="KR231_000677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YybS family protein"
                     /protein_id="HBH0003088.1"
                     /translation="MNNKIRLSKAMSIIVLAIIIALVIAYIPMLGIFSMLAAVPYVII
                     GAITDRKYSLISILVTFCVLILFADISYALNICIMYSLPGIVIGKMLKRSFEQEDSNK
                     FEPIYGGTIIFVLSMLVYFFVLKTFLNVNLLDEVSKMISEIVNIQKNSFSATELKVFD
                     KMKPDEIVSYFTNMLPMMLFLQGLLSAFVTYYLSVFFIKRITKMNIRFPKFADFYLPG
                     NAILTTFLLYLLVLFIQIIGSKLYTELIMTNLQLVFNLMFVIQGIAVCIYFLKKWIRQ
                     GPNKIMFFSGIILCLFGFMGISFVGMVDSIIDFRKVRSYKST"
     gene            29126..31120
                     /locus_tag="KR231_000678"
     CDS             29126..31120
                     /locus_tag="KR231_000678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DHH family phosphoesterase"
                     /protein_id="HBH0003089.1"
                     /translation="MSNKQTFKLNMPEINLYIIVIGISSIILLYYNLYVGCLFFCIFV
                     YMVFHNWRTTNIRRHEWTEYIQNLSLDIDETTKKAIINLPIPLCILEFDGNISWYNGK
                     FYDMIGQKDLLDKNIEDIVKNLNLRKVLNENKEMYTEINYKEKEYTIIYNVIKNDQEK
                     NPKYLMILYWIDKTEYLKVKQNYDDEKNAMMLIQVDGYDEVLKSAAEDKRALINVEVE
                     KILSALELNSNGALRRTSKDKFFLVMHKKELKKLEAEKFSILDTIRHIDYGNNLPVTI
                     SIGIGIDGDTLNENLKLATGALDLALGRGGDQAVVKTKDKFVFYGGKSKAVEKKTKVK
                     SRLIGHALREVIQQSDQVYIMGHKYPDMDAMGAAVGVYDICKSCNKTANIVLQSVNES
                     IEIFINKINENNYYKKLFIGKEEAIDNCTKNTLVVVVDTHRPNYTECEELLKLSEKVV
                     VIDHHRRGVEFINDAVLLFHEIYVSSTCEMVTELVQYMDEDVTINKLTAEGLLAGISL
                     DTKNFAFKTGVRTFEAASYLRKVGADTIEVKKFFNSDVKDFIIKAEIIQSTKIINNRI
                     CLAYSSTEIDSINVIIAQTADELLNIKEVEASFVLGEKDDTIFISARSLGQINVHVLM
                     EKLGGGGHIDIAGAQLKNVSLKEAYKMVNKIIEEYLEEEE"
     gene            31121..31570
                     /locus_tag="KR231_000679"
     CDS             31121..31570
                     /locus_tag="KR231_000679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L9"
                     /protein_id="HBH0003090.1"
                     /translation="MKVILLKDVKGTGKKGEMKEVSDGYARNFLFPKKMAVQADSVAI
                     KELNEKNKSKEIKAQKEYEEAVLLGKQMEEINIEIYSKAGEGGRLFGSITSKEIAEQL
                     KKQKDIDVDKRKILLDEPIRSLGSTFVEIKIHQKVTTKIRVDVKEKQ"
     gene            31589..32917
                     /gene="dnaB"
                     /locus_tag="KR231_000680"
     CDS             31589..32917
                     /gene="dnaB"
                     /locus_tag="KR231_000680"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replicative DNA helicase"
                     /protein_id="HBH0003091.1"
                     /translation="MEDMTRIPPHSVESEQSILGSILLDKDAIITVTETIKPDDFYKE
                     AHKIIYECMITLSNKGEPIDLITLTEELRKQGHLNDIGGISYITSLSTIVPTTSNVKY
                     YADIVKEKSVLRKLIKASNEIINLGYSGATKIEDVLEQAEKSIFDISQEKTSDDFKSI
                     NLVLMDAYDMIEKLYTNKSDVTGITTGFKDLNKKINGLQRTDLILIAARPAMGKTAFS
                     LNLVQNAALKGDASVAVFSLEMSKEQLVQRMLSSQSSVELKKIKTGTLNDNDWPRIID
                     AMAVLSDAKIHIDDTPGIKISELRSKCRKLKIEKGLDLVLIDYLQLMEGEGNNESRQQ
                     EISKISRSLKILAKELNCPVVALSQLSRAPEQRADHRPMLSDLRESGAIEQDADIVMF
                     LYRDEYYHADSESKNIGEVIIAKNRHGETGSVELVWLGEVQRFGDKLRDL"
     gene            33122..33430
                     /locus_tag="KR231_000681"
     CDS             33122..33430
                     /locus_tag="KR231_000681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011862026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0003092.1"
                     /translation="MEKISLKYIYPNIIKVLDEINLFRVIDNNLRESIVVYANNVDNQ
                     YHINMTNTNFGNIINICKLEKLLDVDKFMEKVIKYEKEIIEKEEFSKIEEYMLNIGEY
                     "
     gene            33512..34801
                     /locus_tag="KR231_000682"
     CDS             33512..34801
                     /locus_tag="KR231_000682"
                     /EC_number="6.3.4.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate synthase"
                     /protein_id="HBH0003093.1"
                     /translation="MKTVAIVGSQWGDEGKGKVIDYLATQADVVVRGQGGNNAGHTLV
                     VEGKKYALHLIPSGVLNPNTVNIIGNGIVFDPKGFLEELEMFKTDNISTENIKISDRA
                     HVIFPYHKELDALSEEARGDLKIGTTKKGIGPCYMDKTERSGIRICDLMDKDKFAIKL
                     KAQIDAKNEIVKNIYGKEELFDFETIYNEYLGYAEQIRKYVADTSVIVYDAVRAGKKV
                     LFEGAQGTLLDLDLGTYPFVTSSHPTSGGFAIGAGIGPNMIKDVVGIVKAYTTRVGEG
                     PFVTEQINETGDKIREQGHEFGVTTGRPRRCGWFDAVIVKYAARVNGLTSISFMLLDV
                     LTGFDKIKVCTSYKMGDKIITDFPASLDDLAKCEPVYEELDGWNEDITQIDNFDDLPE
                     NAKKYVAKIEELVGVSVDMVSVGPNRAQTIIRRNIFA"
     gene            35127..35202
                     /locus_tag="KR231_000683"
     tRNA            35127..35202
                     /locus_tag="KR231_000683"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:35160..35162,aa:Lys,seq:ttt)
     gene            35209..35283
                     /locus_tag="KR231_000684"
     tRNA            35209..35283
                     /locus_tag="KR231_000684"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:35242..35244,aa:Glu,seq:ttc)
     gene            35288..35363
                     /locus_tag="KR231_000685"
     tRNA            35288..35363
                     /locus_tag="KR231_000685"
                     /product="tRNA-Val"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:35321..35323,aa:Val,seq:tac)
     gene            35397..35471
                     /locus_tag="KR231_000686"
     tRNA            35397..35471
                     /locus_tag="KR231_000686"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:35429..35431,aa:Thr,seq:tgt)
     gene            complement(35854..36846)
                     /locus_tag="KR231_000687"
     CDS             complement(35854..36846)
                     /locus_tag="KR231_000687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HBH0003094.1"
                     /translation="MNEDKIRKILAKYAKRRDDNELLLEHRKNEVYNRIPEIKSIDDE
                     ISKIGLSLAKIVLLNPKSKDEIVKKTKENIESLKVKKERLLAESNIPLDYLEIKFQCI
                     SCKDKGFLPNGEKCSCLKQEIVNEAYKMSNLDRILSQENFSNFNLNIFSPKKGSDGEI
                     SPRENMLNNLSICENFVHDFKKDNSENLLFYGSTGLGKTYMCNCIAKELLDKGNVVIY
                     QTSFRILDILEDYKFRRDTNNQISEDNYKNLFDCDLLIIDDLGTELNNSFTSGEIFNI
                     VNTRLVAGKKIIISTNLTPSQIGNTYTQRTLSRILDKFRILEFTGDDLRWERFK"
     gene            complement(36855..37913)
                     /locus_tag="KR231_000688"
     CDS             complement(36855..37913)
                     /locus_tag="KR231_000688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaD domain protein"
                     /protein_id="HBH0003095.1"
                     /translation="MFFKESNEIDLGEITIPNIFIDIFMPMADGLYVKVYLLGYRQAC
                     DITSNPKFDNNSIAKNLNIPLSDVLSAWKFWEEKKIIKIHDNEEYDNFNYSIEFLDLK
                     NFYIENILSNNSSIKSNTDKVVSTSENPSIRKMFNSINKIVGRYLDPSEKMSIMDIMN
                     KYNMSPDMILCAYEYVKDKTGTSKPVKYIEGIIRNWYDSNLYTPKDVEESFLVRSERY
                     ILYKTIFNELGFSRQPSKSEKELMDTWFDKFNMDIDLIINACSKSKNISNPSISYING
                     IIKNWNEKNIKNLNDLKQKEEERIVKENINKKQINTTQNNNTYKKTKFHNFNETFTQY
                     TSDELDEIIKKSQKEKFK"
     gene            38038..39501
                     /locus_tag="KR231_000689"
     CDS             38038..39501
                     /locus_tag="KR231_000689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M1 family metallopeptidase"
                     /protein_id="HBH0003096.1"
                     /translation="MVIKFNQKVRRTLSVAILFMVLIIGCFIEKDDSLETYKEKTNSK
                     INQYNMDVIFDDETKRLMCNQNVDYINNTKSNIDKIYFHIYPNAFSKKDFAPFEKSEM
                     TRAYPNGFNEGYIDIKNILNNNSKMEYKIKGDKNDILEIELGKELKPNERMSLDIKYN
                     VKIPNSIGRFGYGENTINVTNWFPIACVNDERGWNLKSYETIGDPFYSETSDFHVKLL
                     IPNKYKIAHTGKLIDDKHDNKKMLYEIEAENVRDFAFILSSKFDVNKVDSKGVAINTY
                     NLNKKLSKKATEVAKDSINIFSELFGKYPYKEFSVVASDFFIGGMEYPMLVMIDQSLY
                     NEKNEFLLEYVIAHETAHQWWYSAVGNDEISEPWLDEALTEYSTIVYFEQKYGKDMAN
                     KLIKTMEIQTKSYLSENIFKPANEYKNSTEYSLNVYTKGAIAFNEIRKEVGDKVFFET
                     LNEYYNKYKHKNANGRAFVELWNSKGVDINKIISECK"
     gene            39603..40400
                     /locus_tag="KR231_000690"
     CDS             39603..40400
                     /locus_tag="KR231_000690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HBH0003097.1"
                     /translation="MLKYCSVGSGSSGNCHYIGYKNTNILVDAGLSGKRITTGLKDIG
                     VDADKLKGIFITHEHVDHIKGAGILSRKFDIPVFANIKTWCSMKDKLGDIKDKNMKVF
                     ENDKTYSLGDIIVRPFSIEHDASDPVGYNFYTESDEKMSIATDIGCITQNIKKHLYKS
                     KLVVLESNYDPNMLMMGSYTYALKKRVMSSTGHLSNEDAANFCVELINEGTESILLAH
                     LSKENNFPELAYETSKGVLASNDIVVGQDVKLDVLSRNDVSNVYEMK"
     gene            40413..42515
                     /locus_tag="KR231_000691"
     CDS             40413..42515
                     /locus_tag="KR231_000691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC/EAL
                     domain-containing protein"
                     /protein_id="HBH0003098.1"
                     /translation="MLKRNFENVEDNKILYSIKQGMILAIPAIMTGSTALVILNLPIK
                     AYQEYLSGLFNGEVTNILNFINDSTLGIISLIILLTISYSYGKIYGSKYTVLVPIVAM
                     CSFLVFSHGNELNSYIEIFKTKWLFTSIIVSMTSSVLFVKLTESFVTSVKFHTEGADA
                     DFNMVVSAIVPFIIVVFLFSIFRVVMISLIGSSNFQDIFYNLFSNVFNKMGTNLMSAL
                     LFIFLMHFMWFFGIHGSNVLDTVAKNLFENSMAININLVNNNQLPTEIFTKTFFDTMV
                     LLGGCGSLLCLVIAIFLSEKRINVRKLAKIASIPALFNINEMLVFGIPIVFNYIMFVP
                     FVITPIILTVTSYVAMSTGIVPCTVSAVEWTSPIFLSGYMSTGSIRGSLLQVFNLCVG
                     VMIYIPFIKMSQNRYTYMFKNNIENLTNLLKRYELTGEQPNLLNHNGKIGSISKMLAS
                     DLKFAMKRGEIELFYQPQVNYNGNVVGAEGLLRWKHSIGGFIYPPLVIILAKEEGFLD
                     ELGEYIINKACIDLKKSEKLLRNPVKFSVNISPDQLDDPKLPEQIKNIISSNDINPNM
                     LGIEITEQIALSGSQIIIERINAIHNLGIKLIMDDFGMGHSSLIYLQNNNFDIVKLDG
                     SLVKEILTNKRSSEIIMTIVNLSKNLDFDIVVEYVENIDQRDKLYGLGCEIYQGYYYS
                     KAIPFEEFVEYANQEREI"
     gene            42583..43062
                     /gene="rlmH"
                     /locus_tag="KR231_000692"
     CDS             42583..43062
                     /gene="rlmH"
                     /locus_tag="KR231_000692"
                     /EC_number="2.1.1.177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001027003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (pseudouridine(1915)-N(3))-methyltransferase RlmH"
                     /protein_id="HBH0003099.1"
                     /translation="MNISIVVVGKIKEKYLKLGIDEFKKRLSKYCKLEIIELDDEKAP
                     ENLSVKEMEIIKDKEGKKILGKIKHNSYVIALAIDGKGLSSEELAKTMSDLAVRGNSS
                     LCFIIGGSLGLSDEVLGRADYRLSFSKMTFPHQMMRLILLEQIYRAYRINNGEPYHK"
     gene            43211..43522
                     /locus_tag="KR231_000693"
     CDS             43211..43522
                     /locus_tag="KR231_000693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBH0003100.1"
                     /translation="MIKIMLACSAGMSTSLLVTKMESAAKENGIESQIWAIPESTIQN
                     EIEKCDVLLLGPQVRYVLPKAQEIAKPYNIPVEVINMMHYGTVNGEAVLNRAIELNNT
                     K"
     gene            43570..43887
                     /locus_tag="KR231_000694"
     CDS             43570..43887
                     /locus_tag="KR231_000694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HBH0003101.1"
                     /translation="MDEKTIEISFNIIGYAGEGKGLAFEAIKEAKNGNIEKAKELLKE
                     SREVINKAHRYQTELIQNEASGNRTEISVILIHAQDHLMNGMNFQQLAEEIVDLHLKL
                     QDK"
     gene            44100..44801
                     /locus_tag="KR231_000695"
     CDS             44100..44801
                     /locus_tag="KR231_000695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBH0003102.1"
                     /translation="MLRNQPLYIQVVDILKQKILNNEYKIDENIPTERELEQEFGVSK
                     ITIRKAIEILESEGYVEKKSGKGTKVISNSLFNKLSKAESFSSILLSKGHKLSKKTIS
                     IEKIINDTNSQVFSIFGEKCSKITRMYYLDSKPYIFFTHYIPFDENLTVESFNNESSL
                     YMYLYRRNINITRFEDEFFIEESELEVSKALNLAKDILLGRKRKTYDENDNIVELSFA
                     RYNTEVQNYVIKYEI"
     gene            45025..46326
                     /locus_tag="KR231_000696"
     CDS             45025..46326
                     /locus_tag="KR231_000696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBH0003103.1"
                     /translation="MEKFASFLERKIMPVAAKISNQRHMRAVRAGIIATLPLTIVGSF
                     FTILLNIPIDAYMDFIAPFKAILDIPFRYTVGFLSLYATFGIASSLAKSYDLDTTGVG
                     MLAVMAFLVSTIVPTQVVEPVGGVIEAGRWMDMAKLNSPSLFGAIVTSLITVEIYRFM
                     KEKNITIKMPAGVPVEVSNSFTALLPTAVILMLFWVIRHILGFDISVALSAMLSPLKG
                     FLSGNSLGGGLLTVFLITLFWVLGIHGPAIMGPVIRPIWDMSIAENITAFTEGVSAHA
                     MPNIFTEQFLQWYVWIGGAGATLALVVMFMFSKSQYLKSLGRLGFLPGLFNINEPIIF
                     GAPIVMNPILGIPFIIGPIIMTILSYVLTITGVIPMMVARLPFAMPAPIAAVMSTNWS
                     ILAGILVLINFVISFAVYYPFFKVFEKQQLQREQEEMSENL"
     gene            46463..47557
                     /locus_tag="KR231_000697"
     CDS             46463..47557
                     /locus_tag="KR231_000697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF871 domain-containing protein"
                     /protein_id="HBH0003104.1"
                     /translation="MERRLGISVYPEHSNMEDDKAYIKMASKYGFKRIFMCMLSITRP
                     KEEVKKHFKEIITYARELGFEVILDIAPNIFDILQISYDDLTFFSELNASGIRLDYGY
                     DGSKEAMISFNPYDLKVELNMSNDVAYLDNIITYKPNVNNIYGCHNFYPQRGTGLPYD
                     FFVRCSNRFKKYGIRTAAFVNSKYATIGPWNINDGLCTLEMHRNLDIATATKHLFATG
                     LIDDVIVGNAYASEDELKRMSEVNKYQVVFNVVTEEKTSEVEKTIMANEQHFRRGDIT
                     NQVARSTEVRKKYAKENFPKHDNTTIFKRGDVVIGNDDFGKYKGELQLILQDCADERK
                     NKVGRIKEDEIMLLDFIEPWSKFKLILEGE"
     gene            47559..48692
                     /locus_tag="KR231_000698"
     CDS             47559..48692
                     /locus_tag="KR231_000698"
                     /EC_number="3.5.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase/deacetylase family
                     metallohydrolase"
                     /protein_id="HBH0003105.1"
                     /translation="MKIDILIKGGKTVDKSIIDIAILDDKIIEVKNQIDDSKYQANQI
                     INLDGEKFISAGWIDIHTHCYERLDLYKDYPDEVGIKSGVTTVVDAGTTGALDIGKFY
                     EDTKKYKTNVYALINIAKQGITSQDELSSMMNIDEYELKRAVKKYKDFVVGIKARMSK
                     SVVISNDVEPLKVAKRIKNELNLPMMVHFGSSPPTIEDIFDYMEKGDILTHIYNGKPN
                     GILRGNEVKKEIIEARERGIILDVGHGTESFSMDIAMKSKDAGIFPDTISTDIYIKNR
                     INGPVYNLSTTMEKFIYMGYSLEDIIDKVTKNAADAISLKNKGLIKEGYDADLTIFDV
                     VNEEKELQDSLNKSVITSTSIKPRAVVVNGEYLNIGKSIGENE"
     gene            48710..49819
                     /locus_tag="KR231_000699"
     CDS             48710..49819
                     /locus_tag="KR231_000699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DgaE family pyridoxal phosphate-dependent
                     ammonia lyase"
                     /protein_id="HBH0003106.1"
                     /translation="MSSIFEKYSVRRVINASGKMTILGVSTVDKEVIEAIGEGCKNFF
                     IIEELINKTGEYIANLLGCESALIVSSASAGIAQSVGAMIAKDDMSLVYNVNNPKKQV
                     KREIIIPKGHNVDYGVPVEVMIRLGGGEVVEAGYANMCNKEHIIREINENTAAIMYIK
                     SHHCVQKSMLSVLDAVQVAKEYNLPLIVDAAAEEDLNVYYELGADLVIYSGAKAIEGP
                     SSGLVIGKKKYIDNVKLQSKGIGRAMKIGKENIVGLTCAIERYISNDKVTLKEMEDKL
                     NPFIDKINTIKGVSASITRDSAGREILRGEIDFNEDIINKSTQQIINELRSGEIAIYT
                     RDYKANEGKIEIDIRSVTGSDLDTIYNRIKNIVES"
     gene            49884..50624
                     /locus_tag="KR231_000700"
     CDS             49884..50624
                     /locus_tag="KR231_000700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KDGP aldolase family protein"
                     /protein_id="HBH0003107.1"
                     /translation="MNCIPQYYKNRVCLNVLAGSIKNAKEVYDACDGYVLIGVLSKNY
                     STVEAAIEDMKKYSKEIDNAISVGLGAGDPNQSNMVSQISKELQPQHINQVFTGVATS
                     RALLGQNDSIINGLVSPTGKPGFVKISTGPLSSKEKDGIVPIETAIAMMKDMGGSSIK
                     FFPMGGLKTKDEYIEVAKACAKHNFYLEPTGGIDLDNFKEIVQIALDAGVEKVIPHVY
                     TSIIDKETGETKVEDIGVLYKIMKELLG"
     gene            50629..51621
                     /locus_tag="KR231_000701"
     CDS             50629..51621
                     /locus_tag="KR231_000701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar kinase"
                     /protein_id="HBH0003108.1"
                     /translation="MNILAFGEIMMRLSVPDYKFLTQTNELNYIITGTGLNILSGLKN
                     FGYNTYMLTKLPNNNVGKASSANIRKLGVKDDFITYGGNHIGVYFLENGYGERPSEVT
                     YLNRLNSSFCESKLQDYDIDKCLEEMDIVLICGIAMQLTDSIKEIALELARKSYEKGI
                     KVFFDFNFRQSLNPERTYDDLVNDYKKILPYCHGLFASYRDINKILNIDSLNIKSSSE
                     LIKKEYDIGIVAGTMRRFDDMNNRFIKGYISNDDGYFESREYKLEIYDRVGAGDGYVA
                     GIIYSYLENMKSEDIVEFGVASSVLAHTTYGDNSLVSTGHVLRLMNNEKIDILR"
     gene            complement(51809..52690)
                     /locus_tag="KR231_000702"
     CDS             complement(51809..52690)
                     /locus_tag="KR231_000702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HBH0003109.1"
                     /translation="MNTKQLEYFISVAENLSFTKTAEKFYISQTAVTQQIKALEEQIN
                     VTLFTRSKRHVELTPAGKVFLSEARTIIKNINDAIAKTQQFAHGFFGTLSIGTLIGYE
                     KNKLQQYLKEFSNTYPNISMDICTNEITELLNLVKNNSMDLAFVINPENQPLKDFEYK
                     TVERYSLVALLPPGHPLYNEDSIDLIELQHDKFIFVKETGDEYGQKSMIQNRYREAGF
                     VPNVVQRSNNLNTIESLVSSNMGISILPSFCVTDTMIERDIAIVPIKEVENRIEVVVV
                     WNKKNTNPALEKFISII"
     gene            52963..54351
                     /locus_tag="KR231_000703"
     CDS             52963..54351
                     /locus_tag="KR231_000703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0003110.1"
                     /translation="MEDKFYAKGNGNNGYIKNLEVCSFNNLDGTCGMFQMALYKRDEK
                     YYLYGCCFGGNKKNGVMISDITDPYNPQFIKHFQMLDPKEYPTTTTPKIQIADDLMIV
                     AMSCGSGPGALVDQAKLANIKCEAGIRIYSLKEDPLNPKFLGYWDCGLKHVMGVHRFM
                     YNGGRYVHLSSDCVGFEGLIYRVIDIINPTNPVEIGKWWRPDQYADGYPNRTFDAGAP
                     HCPEFMDKGWLHGPPFVRDGKAYCGYGGAGLVVLDVEDLTRPRCLGELPFMPAFSSRL
                     AGARTHTALPLPGRDLVVVQNEGERFQFFKPDNITDVQAMNNIHMVDVSDPTKPTLIA
                     QFPYPEVPKDFPYPNFNVAGLGKPGPFGPHNLHEPMDNKPWLEQRGDRVYCCYFHAGL
                     RVYDVSDPYYIKELAYFIPPNPNKTPEESYFPGFPGPRLAVTEDLIVDDRGYIIIDAL
                     DDGFYILKMKED"
     gene            54379..55332
                     /locus_tag="KR231_000704"
     CDS             54379..55332
                     /locus_tag="KR231_000704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HBH0003111.1"
                     /translation="MKILGISFGTKNGNNDTMCKVALKGAKEAGAEVEFIQMSSINIK
                     HCTGCCACVKTLLSGKGSMCVLKDDFEWLLDKMKDADGIVVSDPIFEEGASGLFHTIM
                     DRFGPRADRGNNIIGTKVAEAIGGKIPDSRMLNDKVISFMGIGGSDWGTRVQCEHAML
                     ALIPMWKVIDNAWFPWAKELVMDDTRLVQVHQIGLNIVEAAKDFEKASYQGEEGVCPH
                     CHNRLFYLEPGTKKAICALCGIVGELDTISGKTIFSFPEEQLGHAHDTLPGKFIHGDD
                     IKKMEGHYAEVRKTQEFKERKTSYNFIETLTKEKQAGVSLG"
     gene            55392..55616
                     /locus_tag="KR231_000705"
     CDS             55392..55616
                     /locus_tag="KR231_000705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0003112.1"
                     /translation="MNEKPSFKQIEVILAVIFLVLTYYKVRLTPAFIVIFIPLYLSYF
                     AVSMIVNQIAIKLLEIRQAREATNYNIGNG"
     gene            55609..56121
                     /locus_tag="KR231_000706"
     CDS             55609..56121
                     /locus_tag="KR231_000706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1097 domain-containing protein"
                     /protein_id="HBH0003113.1"
                     /translation="MDRKKKEILTLSMGIALLPPLWAVLAPYIGIKTGAVALICAGLY
                     VTNGNKQEDGLKIMFGFWCGDLWAVLAILIMGYMNFNQNLELFLTLSILGFFAVVIAS
                     LFEKIIFLPSWLCGWAIGLTIMTGENIINLQDICIQIAVAMAVGVWYVGAGVDLFTIY
                     ILSKDRKKGN"
     gene            56153..57007
                     /locus_tag="KR231_000707"
     CDS             56153..57007
                     /locus_tag="KR231_000707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011862019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA hydrolase"
                     /protein_id="HBH0003114.1"
                     /translation="MAMGFEFKIMRSLIYVGLAKEEYRPKLMDWLYRHHIPDSISTFG
                     PYCTKYAFYQAYPTPNEGERFGARKMQLTEHYWLVDEHMPEMANRIMTEYMPMDVLRW
                     QGCIPDVENKRVHENAESGDAGRAVGGDNGCPPFIFAFVPINWEEDFRGKGRTVQDGP
                     NYRWQFMIKYPDGISKEEGEKWFYDEVVPYFTNCCYVNRFVSSKIMINYGATAFDRVS
                     ELWFEGEEEWYKAVVEETKSFIKKPEWAQEEEFPYLKPQFNIASVFLGDIATMDAYSQ
                     YRGYIPMR"
     gene            57541..58335
                     /locus_tag="KR231_000708"
     CDS             57541..58335
                     /locus_tag="KR231_000708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HBH0003115.1"
                     /translation="MYTIGQVSKFLGISRDTLKFYEDKGLVNPKKNDENGYRIYNQVD
                     IYDIATINFYREIDIEIKKIQEIRKSKSINNLELLLEEKEQIILKEIEYKKLLLKKVQ
                     LVKEDCDKIKTYFGKYTIKEMKPLEVKGKIKHVTNYEEYEALKENTNNLKKAVTLTDL
                     RRVINFNEEGIIEEKFIIVREVDDYNKIIEGEVLSHPNCIYTIIEDGRWSTGGENIDN
                     KVEDRLREIAIENECELLGIVYVNILLTTYEEGIERIFLEIYAPIK"
     gene            58439..59245
                     /locus_tag="KR231_000709"
     CDS             58439..59245
                     /locus_tag="KR231_000709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011862018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HBH0003116.1"
                     /translation="MRTEKSLKRPIASFIILTNIIFLPLFLLVVVTIMLKLPTVISDI
                     ALCISAWSSTFAFMILFKKIYPGKKFLVHVKDRFRNKLKFSTVSIIISIQVLIAVVVI
                     FILASKNHGIMPNFTVSSWGAFIYLFLKNLFAGSLGEELGWRGFVQNHLQKRHSPLKA
                     SITVGFWWGMWHLPIWFTTGFKGLDLIKYIIFFMIAIISISIIMTTFYNLNKTLIIPI
                     AIHQLFNFLIGIINEDLIELINYYAMLYLIFAIALIVINPGNVLYKNIRE"
     gene            59307..59828
                     /locus_tag="KR231_000710"
     CDS             59307..59828
                     /locus_tag="KR231_000710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003374619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HBH0003117.1"
                     /translation="MVLLIVDAQKLITNERLYKFNEFVVNVENLIDTARKNNIEVIYV
                     RHDDGVENELTKGKNGFEIYEKFKPCNGEKIFDKKVNSAFKETGLLEYLTNNGEKDII
                     IAGLQTDYCIDATIKCGFEHGFNIIVPAYSNTTVDNFFMSAEQSYKYYNEFIWNERYA
                     KCISLEETLRKMK"
     gene            60243..62330
                     /locus_tag="KR231_000711"
     CDS             60243..62330
                     /locus_tag="KR231_000711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011862017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HBH0003118.1"
                     /translation="MVVDKEIVSILQILLNSTLITTNGLQEESNSSKRQITYRINKIN
                     DMLKVKNVPLICLRADKDIIVRKETKKAIKEILEKNYSKNTYYFSKTERLLYMYLMLF
                     INMEDISINHFINSIKVSRSTVNLDFKDLIPELEKKNIKVKNNRINGYYIVGNEMEIR
                     RVLIKNIIETLSNEKSSRVFDIFIKEYNLDSFEEAKKIILKLIKKYEITFVEDRLIEF
                     IYIFIFLKARMYSTRIVTQENVDIPNISVMSSMKEYKFAKELLEVYGSEDKIKPHNIM
                     YISAWILGISVGNYEEDTEDKDVISKIVNKMMTKFGYLSGVYYISQEKIFKQLYSHFR
                     PAYYRLLFKLPIYNPICEKVKEEYKLVYRIVSNAMKEFCGLFGEEIQEEELAYLTMHF
                     ATLFSNKKEFDGFRKRIALIVCSNGVGSSAILHAELTNLFPDLHFIPMSESVGLENIS
                     EPVDIVFTTNYNAEGLKTDVPVIKVSPVMTTKEKYKITREVYIQLGDIFLRQPKIDEV
                     MDIIKKYANVTSESILSSELLAYFTQIENFTSKEGEGPMLSEITNETLVKIKVKAKNW
                     EEAIRQSASVLVENNKVTEGYVDAMINSAKASGPYIVITKHVALPHARPEAGSKEIAI
                     GIATLDSPIEFGNNENDPVKYVFCLSAIDNNSHLRAMSELVELLEEDEFFKVLDSAKE
                     AKEIIDFIKTHEL"
     gene            62345..62632
                     /locus_tag="KR231_000712"
     CDS             62345..62632
                     /locus_tag="KR231_000712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBH0003119.1"
                     /translation="MYKILIACRAGVGSSLMLKIKTQQIIKENNFPIEVEHGSLDSLN
                     GFNGDAVETLIDVAEELKNKNLKFDIIGIHNIVDRNEIKTALEKFLASKEG"
     gene            62659..63930
                     /locus_tag="KR231_000713"
     CDS             62659..63930
                     /locus_tag="KR231_000713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit IIC"
                     /protein_id="HBH0003120.1"
                     /translation="MEFIISLLSTPAVLLGVVACIGLILQKKSAVEVFTGSSKTLIGF
                     LIFGIGASAMTGALQNFNKLFQHGFGITGVIASPEAATALAQGTYGFAVSCTLILGFI
                     LNLVFARITKFKNIFFTTGHSLFFSCVLVLIMKAHGFDNTITILIGGTILGFMSAALP
                     QFCQPFMRELTGGDEQAIGHFNMIGYGLSGYIGRLFSKHKDDTTETIEFPKWLSIFRD
                     FLMGLSIVMLILFYIATLKAGQAFTQEIAGSTHWLVFPLIEAFTFVAGMSILMSGVRM
                     FLAEITAAFVIISEKYIPGSRPALDVPTVFPYAPNAVIIGFISAYAAGLLAIAIMASF
                     PSIFPVVIIPAAHICFFSGGTAAIFGNTSGGWRGAIAGSFVVGLLLAFLPVILYPVYG
                     TLGIEGATFPNIDYNVVGSILHNILQFIKPI"
     gene            63988..64587
                     /locus_tag="KR231_000714"
     CDS             63988..64587
                     /locus_tag="KR231_000714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HBH0003121.1"
                     /translation="MENTLSEFLDNISNELSEFIASIDETSINKACELILEAEKNHGR
                     VHVTGIGKPGHVSGYISSLLSSTGTSAYILHGTEAVHGSSGQVVEGDVVIAISNSGET
                     QELKATLKTLKVNGAKIIGVSGNESSFLKNISDIFLFAGVKQEGDCLNKAPRASILAE
                     TIILQSLSVVLQYAKGLNTQQYLKWHPAGSLGKSIREGI"
     gene            64592..65497
                     /gene="dapA"
                     /locus_tag="KR231_000715"
     CDS             64592..65497
                     /gene="dapA"
                     /locus_tag="KR231_000715"
                     /EC_number="4.3.3.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate synthase"
                     /protein_id="HBH0003122.1"
                     /translation="MKYKGIICAMITPFDENQNINSQATCQLIDYLIEKGIYGLFILG
                     TNGECHVLTDDEKVEFAKIVINHTNNRVPVFVGTGGNSTREVVDLSKRMEAIGASALS
                     IITPYFVTPTQQELILHYKTIANSVNLPIIMYNMPSKTGINIEPESVRELSKIKNIVG
                     IKDSSGKLDNMKAYIEATKNENFSVFSGSDSLILDSLKAGSQGAVAATTNFLTEIGIS
                     IYENFMKGDLEEAQKAQSSIEELRRILKLGTIPSVMKKTIVLNGINVGTARLPVTEPT
                     GEVLEEIKRVVENYRTILNKSSENR"
     gene            65603..66235
                     /locus_tag="KR231_000716"
     CDS             65603..66235
                     /locus_tag="KR231_000716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketohydroxyglutarate aldolase"
                     /protein_id="HBH0003123.1"
                     /translation="MKKMNITKRMSECGALAIVREENLNRACEIAEGCIKGGITVIEM
                     SYTLNNAGEIIQGLNKKYGETLCVGAGTVLDSETARHAILHGAQFIIAPNYNEGVAKI
                     CNRYQIPYAPGCTSLTEAVDALSLGATFIKAFPISDFYGPKLVKVFKTPIPDMPVLAS
                     GGINIENLHIWLENGVDVCGFGGLLTKGSVEDIAKNAKKIREIIKNIRKI"
     gene            66713..69220
                     /locus_tag="KR231_000717"
     CDS             66713..69220
                     /locus_tag="KR231_000717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011862014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diguanylate cyclase"
                     /protein_id="HBH0003124.1"
                     /translation="MKEDIRLHRMCKKEQATKNEVISEDILKSMSIGVSKHFLDDSFT
                     IIWGNTSFYQLLGYTEEEFLVKFSSLKDYYEQNLYHFESMKNHFLEAYHHGEKSIEYQ
                     ICISANNGDPVWVIMTGILIESQDNEKSMVYILYSKINELKIKQEELSDMEKESTENF
                     KWMMSEYAGNVYISDMDTYELLYLNKHSCNTLQASANELIGRKCYEVIQGRTSPCPFC
                     TNSYLKKDDIYEWEFYNKKLKRTFIIKDRMLNWQGRRVRIELSYDMYSAEYKLAKKDQ
                     ERESILKTIPAGMVRLDARDYLTILWCNDIFLNMIEYTKEQFAEELNNQCGYLFSEDY
                     KRSKKLAQDLKESGDNVVFEAKIYTRSREERIWTVTLCYISGEDSWDGIPSFYSIGID
                     ITKERKQIEKLQHISEKDALTGIYNRAETERQIKKYFEKNLNVMGALFMIDTDNFKQI
                     NDTEGHMIGDIVLTEMASGMKKIMRDSDVVGRIGGDEFTIFMKNISSVKDAEKKAEEL
                     LYMFRHLFQKEKSFLKVTCSIGIAIYPKDGTTFKEIYARADKALYQAKNMGKNNYVIY
                     NQDYFKELEEFDCSSLGTVIDSEKQYAEYPDNLTRYIFRMLYQTDDIDQAINMILEVV
                     GKQFDVSRVYIFENTEDGRYTSNTYEWCNEGISSQMAYLQNSNYQDYEDYEKLFEDEL
                     VFYCRDIHTLSPKLEELFSSQGIHSTLQCAYKEDRVFSGFVGFDECTGLRLWSQEEIS
                     TLSLISQIISMFLQRKKNNKLNQQIQQYQNILDNIDQCICVINKENNFLLYVNKKFKN
                     TYSKFQIGQPYYLDSIDIHKISIIWNKKEAYLCTSTI"
     gene            69562..>71585
                     /locus_tag="KR231_000718"
     CDS             69562..>71585
                     /locus_tag="KR231_000718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1430 domain-containing protein"
                     /protein_id="HBH0003125.1"
                     /translation="MKKIIYVLFTIELLIVSLLGLNIVKDNEINNILYNETTSISVMF
                     KDYKKLNKNYSKWIKDIADENNVTISKYVFNNNEKLSIYTTDTSLNNNIKLKSGKFPN
                     TNSNEFISNINTNNSNQVGKFSTMSKDISILIRDFGKISEVGESGILYISTQNEDTIN
                     KILRELNVDRSIFVARLHDRYVNSNLYLNPSIIRDLILIILCFLATIIHYSISVSREA
                     SILRLNGYSKLDIIARVIKNILRIMILSSVTALLIYIIYILKLNIGVRACLYFAMFSI
                     ICILINILISILIVGFNSRSSKYVLSLNGKKSYGFVNIMHFTLKIVFVSFLILSINNC
                     ILNYNMLQTQLGNLSEWDKAKNVYNLTLKDTGEQSLGKEEVIKNAKIKGFYKNLVEEK
                     DAFLIDSTNFEKLEDGSYMYEINSKGKNPEVSQYGKNIKINKNYLKVNPIYSNGKEIF
                     NLIDYDDKTINLLVPKKLQVHENEIKKEFRELFYFEKIEVENMYNKELNRALNKTKKS
                     DLNVNIIYVDNNQSYFTYNSLVMDDNRNLIDDPIAIVDIDNIDDSFYLSYISRCVYFN
                     SKKLDALADISSIIEAQGVEAHIQSLHAVYNEYGLEINKLEKYLNSEIFTIIIIAISN
                     LMITYNIVASYYERNKYKLYIKKIFGYSTTARSMLLIVSLILTNIIPIGI"
BASE COUNT        27294 a         8539 c        11943 g        23809 t
ORIGIN      
        1 atataaatta acctactgtt taattttcaa tgttcgtgtt tatttcttgt tccttttttc
       61 aaggacaagt aatactatac catctttaaa acagtaggtc aatacttttt ttatattttt
      121 ttataaattt ttttcatatt cttttttcag cttctctact acctttttct ctagtctaga
      181 aacagtcatc tgtgatatcc ctagttcttt agctatacta gattgtgttt tatcaaagaa
      241 aaatctatct ttaaaaattt taacttctaa ttcatttaaa gtttcaataa acttattaat
      301 aaaatcttca tactctatac ttccaaagtt accttcttct tttccaatct tatcaataag
      361 agttatatct ttatcctctg aatcatcatt acttgatgaa tccaaagaca ttggttgata
      421 tccataagaa gcctccatag cctctaaaac atcttcttca ctaacgccta tataatcagc
      481 tatatctttt acctttggat gcttcttatt ttcttgttct aatttaatct tcgcatcact
      541 tatctttttg cttaattcct gtattcttct tgggactcta agtgtccata ctttatctct
      601 aaaatacttt tttatttctc ctactatagt tggtgttgca aagctggaga actcaaatcc
      661 tttctcaaca tcatatctat caatagcata aattaatgcc aatgaagcaa cttgatatat
      721 atcttcaaaa tcaacacctt tgtttatata cttcttagct aacaatcttg ctaaatacag
      781 atgtctttca ataagaatat ttctaatgtc tacattttta tttttattat ataaattaaa
      841 tagctctttt gtatccatat ttaggtaatg tgtagcatta gctacatttt tcattaaata
      901 tcaactccta aatatttagt catttttatt tttgtccctt gattatgttc tgattcaata
      961 tctacatcat ccattaaagt tttaattata aacaatccaa gaccactctc ttttggattc
     1021 tctaaatctg gtgtacttat tgagctaaca tcatatcctt ttccattatc ttgaatttct
     1081 atattaattg cattatctaa aatattaaat actatattaa atacatcatc tttactgtgt
     1141 tttattgcat ttgtacatgc ttcagatact gctaccttta tatcttctat atcatctatt
     1201 ggaaaaccca tcttattggc aattccagat gctgttaatc ttattatact aacataatct
     1261 ggatttgtag taatttccat ctttatagtc tcacaagcca aagtttatcc ctccacttta
     1321 aatattttat ctagacctgt tatagtaaaa atctttctta cgttactctt aggatttact
     1381 atgtatatct ctttttcatt tatttttaat ttttttaata cacctatcat agctcctaag
     1441 cctgttgagt ctatataatc taaatcttta agattaatct ttacatctaa catatttttt
     1501 tctattaaag catgtaaatg ttcctttagt ttatctgctg tagaaacatc aagttctcca
     1561 tcaagacaaa cattccaaaa tttattttgt gaatctaaat ttgaatcaat attcatagac
     1621 atgtaaaaac ctcctatttc cttttaataa ttttaaatat atttcctata ctcaatattt
     1681 tattaattac ataaactata tcatctattc cctttgatat tgatgatgca ttttcaacaa
     1741 tatcttgtat atgtctttca ttataatcta caatcttata tgccttttca acaaccttat
     1801 ttatgctgtt tagagtttta gctaaataaa ttgctactat aagagcagag cttcctacta
     1861 acactgctcc aatttgccac ccccatgcat tcattagtta acatctccct catcatcaaa
     1921 gcttttactt attactatat cttcttctga aatctttata tcttcttcat tattatcatc
     1981 atccactaaa tttattattc tctctttaac atcattaaat gtttcatgta gaacttcttt
     2041 tggattttct ttaacatcat taaacttctc ttttgtttct tttcttagtt cagaaccttt
     2101 tttaggtgca aaaaacatac caaatataaa ccctaaaata gctcctaata ataaaaatcc
     2161 acctttttta caacttcttt tattgcacat aacaattact cctttcaatt ttaaattttt
     2221 atctaactac attatacaaa aagaatagga tatttatcct attcttcttc aatatttatt
     2281 ttggcaatcg aaactacatt gacttcatca ttcgtcttca ttaatttaac accacttgta
     2341 actcttccaa acagtgatat ttcattgact cttattctaa taagaactcc atcagaattt
     2401 ataatcatta tctcatcatc ttcgttgacc atatctgcac ctacaattgt accagttttt
     2461 tcagatatat tataagtttt aattccttta ccagctctta tttgacttct atactcttct
     2521 atatttgttc tctttccaaa accattctta cttacaacta acacatctgt acctttactg
     2581 caaaggttca tagacacaac aaaatcttct ttacttaaag ttataccttt tacacccatt
     2641 gctgttctac ccatatatct tatatcattt tcatcaaatc ttatagacat accttcttta
     2701 gttactaaaa gtacttcttg ttttccatct gtaagttcta ctccaataag ctcatcatca
     2761 tctcttaaac ctatagcaat aagaccagat ttatttatat ttttgaactc ttctctctta
     2821 gtctttttaa caataccttt tttcgttgca agtaataaat attcattttc atcattacca
     2881 tcaataggta ttagagtagc aattttctca tctgctgaca attgaagtaa attcactata
     2941 gcagtacctt tagcctgtct cttaccttct ggtatttcat atgcatttaa tttaaatact
     3001 ctacctttat ttgtaaagaa taatagtcta ctatgagtag ttgtagttac caagtgcctt
     3061 acaaaatctt cttctctagt tgtaagtgct gaaatacctc ttccacccct tttttgactc
     3121 ttataagtat cagatggaag cctttttata tatccaaagt gagtaagagt tattgctatt
     3181 tcttcatcac ttataagatc tctcatatct atttcgcctt cagcatgtct tatttctgtt
     3241 cttctctcat cagagtaatt ttcttttatt attgtaattt catcctttat tacatttaaa
     3301 agtaatcttt catcagctaa aatctctttt aatctattta tcttcttgat taaatcttca
     3361 tattcagctt ctatcttatc tctttctaaa cctgtaagtc tttgaagtct catatctaat
     3421 atagcttgtg cttggatttc agttaatttg aatttttcta ttaaacctag cttagcttct
     3481 tgcccagtct ttgaagctct tatcaagctt ataacagcat ctatattatc taaagcaatc
     3541 tttaatcctt ctaaaatatg tgctcttgct tcagctttat ttagttcaaa tttagttctt
     3601 cttgtaacaa catcttcttg atgtttaata taatgatata atatttgttt aagatttaaa
     3661 actcttggct gaccatctac aagtgcaagc attattatac taaaagtatc ttccatttga
     3721 gaatgtttat acaaattatt taatactata ttagcattag catccctctt taattctata
     3781 acaattctca taccatttct attactttcg tctcttaggt ctgatatacc ttctattctc
     3841 ttttctttaa ctaactctgc tattctttca accagtttag ccttatttac ttgataaggt
     3901 atttctgtaa ctattatttg ctgttttcct tttggtagct cttctataaa agctctagac
     3961 ctaactttaa cttttcctct tccagttctg tatgcttctg ctatactttc ttttcccatt
     4021 ataattgcag ctgtagggaa atctggtcct tgaacaaatt ttattaaatc atctacacta
     4081 cactctggat tatctatcaa atatacagtt gcatcaatta cttctgctaa attatgtgga
     4141 ggtattgaag ttgccatacc aacagctata ccatttgagc catttactaa taaattagga
     4201 tatctagctg gcaatactga aggctctttt aacgactcat caaagtttgg tttaaagtct
     4261 acagtttcct tttcaatatc tctcagtagt tctaatgata atttactcat tttagcttct
     4321 gtataacgca tagcagctgg tgaatcccca tcaacagaac caaagttacc atgaccatct
     4381 actaaaagtg ctctagttga aaaatcttgt gccattctta ccatagcata ataaacagca
     4441 gtatctccat gaggatggta cttacctaaa acgtccccaa caatacgagc tgacttcctg
     4501 tatggtttat ctggagttaa atttaactca ctcattgaat ataatattct tctatgaact
     4561 ggctttaaac catctctaac atcaggaaga gcacgtccag ctataacact cattgaataa
     4621 tcaatatacg attttttcat ttcttccgct atttcaatag ggagtatttt gttattttct
     4681 tccatgtata ctaatcccct ctctctatat atctaagttt ctaacaaatc ttgcattttc
     4741 ttctataaat tcttttcttg gagcaacctt atcacccata agcattgaaa atacttcatc
     4801 tgcaattgca gcatcttcta cagtaacttg taataaagtt cttgtctcag gattcatagt
     4861 tgtttcccat aattgctctg cattcatctc tccaagacct ttgtaccttt gaagttcaac
     4921 accatttctt ccaatttcat ctaataagat atttaactct ttatctgagt aaacataatg
     4981 ttccttcttt tgctttgtca ctttatataa aggtggctgt gctgcataaa catacccctc
     5041 atctataaga ggtctcatat atctaaagaa gaatgttaat aataaagttc ttatatgggc
     5101 tccgtctaca tcagcatcgg tcataattat aattttatga tacctagcct tatctatatc
     5161 aaaatcttct ccaataccac aaccataagc tgttatcata ttttttattt catctgaaga
     5221 tagtatccta tctagtcttg atttctcaac attaagtatt ttccctctta atggaagtat
     5281 agcttgacta tttctatctc taccttgttt agctgaacct cccgctgaat ccccttcgac
     5341 taagaatatt tcacttttag atggatcttt ttctgcacaa tctgcaagtt ttccaggtaa
     5401 agatgtactt tctaatacac tttttctcct tgttaattct cttgcttttt ttgcagcttc
     5461 tctagctctt tgtgctctta aagctttatc aactatgatt cttgctgttg atgggttttc
     5521 ttctaggaaa gaccccagtt catcaactgt tacactatca actatacctc tcataaagct
     5581 attacctagc tttgttttag tttgaccttc aaattgaggt tctggtaatt taactgatac
     5641 tactgctgta agaccttctc ttatgtcttc accaagtagg ttaacatcat tttcctttaa
     5701 aaatttattt ctcttagcat aatcatttac agttttagta agagctgctt taaatccact
     5761 taaatgagaa ccaccttcat gtgtatttat attgtttgca aaagaatata tgttctctgt
     5821 ataaccatct gtatattgca tagctagttc aacaaaacaa tcatcaacct ttttatctat
     5881 ataaactatg tcatcatgta taccagttct agatttattt aaatacttaa tatattctac
     5941 caaaccacct gtatagtgaa attcttttct tttttcttgt ccttctcttt tatcttcaaa
     6001 tactattttt attcctttat tcaagaaaga aagttctcta agcctatact ccaatgtttc
     6061 atatttaaac tctatttcat caaatattgt ctcatctggc ataaattgaa tcattgttcc
     6121 tttatcttga gattctccaa ctacttcaag cttagatgtt ggcaatcctt tctcatatgt
     6181 ctgcttatat ctctttccgt ttaaataaac ctctgctacc atccattttg acaatgcatt
     6241 aactacagaa acaccaactc catgaagacc tccagatact ttatatcctc cgcctccaaa
     6301 ctttcctcct gcatgaagat tagttaatac tgtttctaaa gttgatttac cagttttagg
     6361 atgtatttca acaggtatac ctcttccgtt atcttttact aaaacactgc catcttcatt
     6421 aatagataca tatatgtctg aacaatatcc ttgtaaagcc tcatctatac tattatctac
     6481 aacttcataa actaagtgat gtaaacctct agggcttgta ctaccaatat acatacctgg
     6541 tctttttcta acggcttcta atccctctaa tacttgtatc tgacttgcac cgtattcttg
     6601 tttcatttaa tttcctccat tctctatgct aataacatcg ccattttcaa tattaaatat
     6661 tgtaacattt ttttcatcaa atattttttt atgtgaaact tcagcacttg ttataaacat
     6721 ttgaacattg cttaaattat ttactaaaag tttttgtctt gcttcatcta actcactaaa
     6781 aacatcatct aaaattaata ctggatattc ttcaacttca ttttttatta attctatctc
     6841 tgataacttt aatgatattg aagcagttct ttgttgacct tgtgaaccaa aaagtcttgc
     6901 atctaaatca tttatgaata tatttaagtc atctttgtgt ataccatatc tggtagtctt
     6961 agattctata tcattaggtc tattcgatga caacttggct aaaaatttat tatatactgt
     7021 atctatagta tcttcatcag ttatatttat ttgattttta tatcgaattg ataatctttc
     7081 aactccatta gtcaaattca tatgcatatt ttcagatata ttagctatct tttttataaa
     7141 gtctctacgc aaaatataaa tataacttcc atactttgct aacgtatcat catatacatc
     7201 taataaagct tcatcaacat gtatattttt aagcacccta ctcctttgag aaagtgtttt
     7261 attataattg gtaagatatt tataatattt aggtataatc tgactaatct ctttgtctat
     7321 aaatgccctt ctttctttag gaccctcttt aaccaacctt aaatcctcag gagaaaatat
     7381 aacaacattt aagttgccaa gtagttcttg tatcttttgt aaaggaactt tatttattct
     7441 tatccctttt ttatcttttc caataattag ctctattaga ctatatttat tatattttga
     7501 aaaacttcct ccaatatata agttttcact attaaatcta accatttctt tatctttgtt
     7561 agtcctaaat gattttccaa aagaaagcat ataaatagat tctactatat ttgtctttcc
     7621 ttgaccattt ttaccaacaa gtagatttac tttcccatta aattccagat gcaacttttt
     7681 ataatttcta aaattaacaa gttgcaaact tttaagtttc acaaaaagtt ctcctttttt
     7741 acaatacttt tattttagtt ccttctattt caactatatc tcctgatttt atcttttttc
     7801 ctcttcttaa ttctatttca tcatttactg tcactaaacc ttcttgaatt aaaaattttg
     7861 catgacctcc tgttgatgca atctctgcta atttaagaaa ttgatccaac tttatatatt
     7921 ctgattctat agttatttca gtcataatag ttcctccttg tcactatttt aaacaaattc
     7981 ctattgatac actaaaagta tattatacca taaatatgct tataaaagga gttgtctaag
     8041 attagaaaaa ttttctacaa aagacaactc cttcatgtct gctatatatt tgatgatatt
     8101 cttactggaa gcagtaagta aatataatta acatcatctg ttggtttaat tatacaagga
     8161 tttacatttg tagtaaattc tataaatatt tcctcattat ctatattttt caaaccttcg
     8221 ataaaatatc tagaattgaa agctatatct aggtaatctc catctaaatc tatttcaact
     8281 tcttcataca catttccttt ttctgtatta gaagtaattg ccattacttt atctcttata
     8341 gataacttta taagattatt tttttctgat tgagacaata aagacgctct ctctatacta
     8401 tttaaaagtt ccttagtatt taatttaact ctgctgttat gttctcttgg caataatttt
     8461 ttataatcaa taaaatctcc ttcaagcaat cttgtaataa ttttcgtatc attaattata
     8521 aaaatagcat ttttttcgtt aaatccaact ttaacattat cctctccaga aagcaaacta
     8581 tttacatcta taagtgtctt tccaggaatt atgactttta tattttcagt taaactatca
     8641 accgaacaac tttttacagc taatctatat ccatcaattg ctactaaatt taagtttcta
     8701 tctacaattt ctaaaagttc tcccattaaa acaggttttg tttggtcctg tgagatagca
     8761 aatacagttt gtttaatcat attttttagg atttcttgag gtatgctata taaatcttct
     8821 tcatttaatt ctggtaattt aggaaattct tttgctgcat aacctttaat tttaaatctt
     8881 gaatttacac aatttatgta aatattattt tctgaatcag tttctatctc aacaaaggaa
     8941 tctggtaatt ttctaattat atctccaaat agccttgcat ctacaacaac atcacctttt
     9001 tctatgattt ctgcttgtac ataagtttct attcctattt cagcatcata tccagtaagt
     9061 tttaattgac cttcttctgt agatataagt atacctttta ataattctat tgttgttttt
     9121 ccattaatag ctttttgagc aattccaatt ctatttgcta ggattttttg attacaaatt
     9181 attttcaatg tggataacct cctctggctt tttatatata aaaataagtt aaaatcatag
     9241 tagtaatagt agtaggtgtt gttgataatg ttaataagta tgtataacat tataaataca
     9301 aagatattaa catgtgtata agatgttaat atctttgtta ttttagactt gataatttgt
     9361 taataatttt tgttcaaaaa aagtattaac aggttattca agagatataa acatacaatt
     9421 gtgtataaat tatcccttca aatctgatat aattttgtct attttagtct taatttcttc
     9481 actttcttct atatccttag atactttgtc atgagcatga attactgttg tatggtctct
     9541 acccccaaac tcttcaccta ttttaggaag ggataaatca gtaagctcgc gcgttaaata
     9601 catagctatc tgtcttggat aagctattga acgtgttctt tttttagaat taaaatcttc
     9661 catctttaaa ttgaatacag aagatacttt ttcttttatt ctgagaacat ttatttcttc
     9721 atttttagaa gttgttataa tatcttttaa agcttctgta gcaagatcaa aagatattac
     9781 cctattgcta agagaagaat aagcaaccac tctagttaat gcaccttcta gttcccttat
     9841 gtttgactta atattttttg ctatatatga cataacctca tttggcacat ctatacgttc
     9901 tagttgagcc ttttttctaa gtatagcaat tcttgtctca aagtcaggtg cttgaatatc
     9961 agttataagt cccatttcaa atctcgatct tagcctatct tctagtgtag gtatgtcttt
    10021 tggcggtcta tcactagata taattatttg tttgtttgct tcatgaagag tattgaatgt
    10081 atggaaaaac tcttcttgag ttctttcttt tcctgctata aattgaatat cgtcgattag
    10141 taatacatct acgtttctat atttattcct aaattcttcg tttttatcgt cttttataga
    10201 gtttataagt tcattagtaa atttttctga agaaacgtaa actacttttg agtctttttt
    10261 ttgactaaca atatgatgac ctatagcatg cattaggtga gtcttaccta atccaactcc
    10321 tccatacaaa aaaagtgggt tataagcttt agctggagat tctgcaactg caacgcatgc
    10381 agcatgtgca aatctattac tattaccaat aacgaatgta tcaaatgtgt attttggatt
    10441 tagattgggg taaagaactc tataatttaa atctgtgcta tcagaattta aatcagcaac
    10501 ctctttttcg ctcaatacaa atttaatatt atattttttt aatgacagtt gactaatagc
    10561 atcttcaatt aaatgtaaat atctattctc taagatatct ttattaaaat cactaggagc
    10621 cagtaagatt aaatcattaa gatgtatttt taatggtacg atgtttttaa aaaaggtatt
    10681 aaaacttact gaagttaagt caccttttat taattgtagg gttttgtccc ataaagaaac
    10741 tatatccata atataaacct ccgaacagaa taattaatat tttccacaaa gttattaaca
    10801 gaaaagcaaa aatatatata aattttacag aataactaaa tttatggata atggtgttga
    10861 taaattaata atagtataaa ttattaaaaa aatatgaaaa gatataaaca atatgtagat
    10921 aaagttataa ataacataaa catacaataa atggtgatta taactagagt attgtcagta
    10981 atcttaaaag ttatacacaa aagtatccac aagctgtgaa taatttctaa taagttgata
    11041 acatttatgc acattatcaa caagtatatt tataatatca aaatatatgt caaacttcaa
    11101 tgatttgtaa ctaatttatc cacaatatta actaattgtt gataaaaata taaacatgtt
    11161 aaaattactt tatttgtgta tataattgaa aaaaataatt tagaataaaa ttaaatagat
    11221 ttttactagt attttcaata aaaaaaatac ataatatata tatggtagat tttgtgatat
    11281 aagcgtccca aaaactcgtt gacaacagta gtaaaagtat ttataattat atgtgttatg
    11341 tttactttga gggtaaagtt attattttta taaacggaaa ataaaatctg aaaggcggtg
    11401 caaaataatg agtaaaagaa cttatcaacc aaaaaagaga caaagaagta aagaacatgg
    11461 tttcagaaaa agaatgaaga cgtctaacgg aagaaacgtg ttaaagagaa gaagagctaa
    11521 aggaagaaat agattaactc attaattaca aaagggccgc tgcaaaggtg gcctttttgt
    11581 gtaaataatt acaattcata gctgtgttta tggaggttaa ctatggactt taataggact
    11641 aaagggttga aaaaagactc tgattttaga aaagtatata aacacggcaa atcttttgca
    11701 aacaaatatt tagtaatata tatacttaaa aataaatcag attatagtag agtaggtatt
    11761 tctgtttcaa aaaaagtagg aaaagctatt actaggaata gagtaagaag attaataaaa
    11821 gaagcctaca gattaaatat tgatgaaaaa attaagcctg gatatgatat agtatttata
    11881 gcaagggtat ctagtaagga tgctactttt aaagacatag acaagtctat aaaaaattta
    11941 gttaaaagaa cggatatttc tatttaattg tatgctataa atatggaggt taatgacttt
    12001 gaataaaata atttatatat taaaggaaat aagtaagcat ttatcgaatt tatgtattta
    12061 tttagtgaga ttttatcaaa agtatatatc tcccttaaag ggacctacct gtagatttta
    12121 tccaacttgc tcacaatatt caatagaggc gtttaagaaa tatggatttg taaaaggtat
    12181 gtatttaacg ataagaagac ttttaaaatg tcatcctttt catccaggag gttacgaccc
    12241 tctaaaataa aagagagtaa ctattaggag gtataaaaaa attgaatata ataggaaatt
    12301 tcttaggatt gattcttaag gtaatatttg aatttgttaa tcattatggt atttctataa
    12361 tactttttac gatacttgta aagattattt tattaccatt aacaattaag cagactaagt
    12421 caacaaaggc aatgcaagat atacaacctc gtataaaaga gatacaagaa aaatataaaa
    12481 ataagccaga aaaacaaaat gaagaaattg ttaagttata tggagaagct aaaattaatc
    12541 cactatctgg ttgtttacct ttattaatac agtttcctat attaatagga ttatttagcg
    12601 ttttgagaga accagttgct catggcgttt ttgcaaacaa agctgcattt ttagcagctg
    12661 acaatgggtt tttatggata aaaagcttaa catcaccaga ttatgtatta gcagtatttt
    12721 caggagcaag tgcatatgtc atgcaaaaag taatgacacc aaaagatcag ttacaaggct
    12781 ctatgaaagt aatgacatat gtaatggcag gtatgtcttt ctattgggga tttatattcc
    12841 cagcaggact tacattgtac tggacagtaa gtaacttatt ctcaatagct caatattact
    12901 taataatgaa tcctttaaaa gctaaactgg ctgctaactc taaggaggaa aaagttaatg
    12961 agaaaaagcc taaaattaat aaaaagtaag agtaaagagg aagctataag taaagctata
    13021 gcagagttga atttaaaagc agaggatata gaagtagaaa tacttgaaaa tccaagtaaa
    13081 gggtttttag gttttatagg tgctaaagat ggtacttatg aaatttttgt tatcgagagg
    13141 gaagtagatg tagctaaaaa ttttatagag gtaatgttga aaaatgcaaa tgttgatgcc
    13201 aaagtcaatg tatctcaaaa agataattta atcatggttg atattgaagg caaagaagct
    13261 gcaagtttaa ttggtagaag aggggaaact ttagattcta ttcaattttt gactggatta
    13321 gctcttaata aaataaataa agattctcat acaagagtac ttgtagatat agaaaattat
    13381 agatcaaaac gagaagaatc tttaataaga tatgctaata aagttgctag agaagtagcg
    13441 aaaacaagaa aaactaaaaa attagattat atgaatccat atgagagaag aataatacat
    13501 tcagctcttc aaaatgacaa atatgtaatt acatatagtg aaggaaccga tccatataga
    13561 agattagtaa ttgagtgtaa aagataaagt caacctccta aacattaggg ggttttattt
    13621 tttaatatta ttaaatcatt aatggttggt taaatgtaaa tctatatgta aaaaattatg
    13681 aattaagagg tgataaattt gtttatagat gatacaattg cagcaatagc tacagcacct
    13741 ggagaaggtg gtataggtat acttagaata agtggagaaa aagctttgaa ggttgcagaa
    13801 gaaatcttta aatctatgtc tggaaagagt attgaagaat acaataagag aacattaata
    13861 tatggaaata tagtggataa tgaaaatgta attgatgaag ttttattggc atatatgaaa
    13921 ggaccaaatt cctatacagg agaagatgtt atagaaatta attgccatgg tggatttatt
    13981 tcggtaaaga agatattaga attaatacta tcaaaagatg ttagattagc agaggctggt
    14041 gagtttacta aaagagcatt cttaaatgga agaatagatt tatctcaagc agaggctgta
    14101 attgatgtta taaaagccaa aactgatata gctcatgaag ttgctcaaaa tcaattagag
    14161 ggttctttat caaagaagat aagagaattg agagataaag tcactgagat attagctcat
    14221 gtagaagttg ctatagatta tcctgaggaa gatattgagc atataacata tcaaactctt
    14281 aaagaaaaaa ctgatgaact taaaaaagac attaaaaaat tatatgatac agctgaaagt
    14341 ggaaaaatac ttagagaagg cttaaagacg gtaattgttg ggaaaccaaa tgtaggtaaa
    14401 tcttcactac ttaattctat tttaggagag aatagagcaa tagttactga tataccagga
    14461 actactagag atgttataga agagtttgta aacataaaag gtataccttt aaaaattgtt
    14521 gacacagcag gtataagaga tactgatgat attgttgaaa aaataggtgt tgaaaagtct
    14581 aaagaatcat ttactagtgc agatttgata gtaatggttt tagatgcatc tagaaagttg
    14641 tcagaagaag atatagagat attagaaaaa cttaaggata aacaaacaat agtgctgtta
    14701 aataagaatg atttgaaaca agagattgaa gaagaaaaaa tacttaaata tgtagaaaat
    14761 aatagtataa taaaaatatc agctttacaa caagaaggaa tagaagaatt gcaagataaa
    14821 atagagtcta tggtatataa aggtagtatc aaaaataatt ctagtttagt agtaacaaat
    14881 tcaagacata aagatgcact tagtaaagca tataaatctg caacagatgc tttaattgct
    14941 ttggaacaaa gtatgccatt tgactttgta gaagtcgatt taaaaaatat atgggactat
    15001 cttggatata ttaatggtga tacagtaaca gaggatttac tagataatat attccataat
    15061 ttctgtattg gtaagtaatg tacaaaagta aacttgtttt tattatagag atttttaaaa
    15121 aatttgaagt gtttctcatg aaacattaat tttgaaaaga aaggaattat aaatgataaa
    15181 gtttgaagca ggaaaatatg atgttatagt agtcggagca ggacatgctg gatgtgaagc
    15241 tgctttggct actgcaagaa tgggatataa aactttgata ataacaatgt ctttggattc
    15301 catagcatta atgccttgta atccatcaat tggagggact ggtaaaggtc aattagttaa
    15361 agaaatagat gccttaggcg gtcagatggg attaaatata gacaagacat atatacaaag
    15421 tagaatgtta aatactgcca aaggtccagc ggtacactct ttaagagcac aagcagataa
    15481 atttaaatat catgaagaaa tgaaaaagac attagaagat gaaccaaatc ttgatatagc
    15541 tatggatgaa gttgtagaaa tacttcatga aggaaatgtt gtaataggag ttggaactaa
    15601 actaggatgt tcatttaaat ctaaagctgt aatattggcc actggagttt atctgaactc
    15661 aaagatatat atgggtgaag ttgcatttta tgaaggtcct aatgcattag ggtatgcaaa
    15721 atatcttaca gatagcttag ttgagcttgg ccttagaatg agaagattta agacgggaac
    15781 tccagcaaga gttcatagag atagtataga cttctctgta atgtctttac aagagggtga
    15841 tgaaaaagta actccattct catttatgaa tgaaaatata gaaaaaaaac aagaaccttg
    15901 ttatttaaca agaactacag aagaaactca aaaagttata ctggataatt taaaaaggtc
    15961 tgctatgtat agtggagtaa tagaaagtac tggtccaaga tactgtcctt ctatagaaga
    16021 taaagtagta agatttagtg ataaaacatc acatcaatta tttatagaac cagaagggtt
    16081 aaatactaaa gaaatgtata tacaaggaat ttcaactagt ttaccttttg aagttcaatt
    16141 agatatgtac aaaactataa aaggacttga aaattgtaag ataatgagac ctgcatatgc
    16201 tattgaatat gattgtgttg acccaactca actaaaaata agtttggaaa taaagggtgt
    16261 tgagaactta tttagtgcag ggcaatttaa tggaacttct ggatacgagg aagcagcagc
    16321 tcaagggctt atggctggta taaatgcagt tagaaagata gaaggaaaag agccatttgt
    16381 attagaccgt tcagaagctt atataggtgt cttattagat gaccttgtta ctaaaggaac
    16441 taacgagcct tacagaatga tgacatcaag agcagaatat cgactatatt taagacaaga
    16501 taatgcagat atgagattaa ctcaaaaagg ttatgatata ggattagtta aaaaagatag
    16561 atatgaaagg ttcctaaata aaaaggctgc tgtagagaaa gaatttgaaa gactaaaaaa
    16621 tgaaagagtt acaccaaaag aagtaaatag tttgttggaa gaaaaaggag caacaccaat
    16681 aaaggttgga atatctctat atgaattttt aaagagacca gaggttactt acgaattgct
    16741 tgaagaatta gggaaaggcg ctggagaaga tgtttcaaga gaagttaaag aacagtgtgt
    16801 aataataact aaatatgaag gttatataga gaaacaattg aaacaaatag accaatttaa
    16861 aaaacttgag aataaaaagt tggatgagaa aataaattat tcatctatag aaggtcttag
    16921 attagaagct agacagaaat tagatgatat aaaacctatt tcaatagggc aagcatctcg
    16981 tatatctggt gtttctccag ctgatatatc agttttactt atatacctag aacaaatcag
    17041 aagaactaga ggtggcaaag gtgaataata tagaacttct gaaaaacggg attgaaggtt
    17101 ttaatataga tacgaatgac agtatgttag aaaaatttaa aatctataga gagatattag
    17161 ttgaatggaa taaaaagatg aatcttactg gaatagaaga tgaaaaagaa gtgtatataa
    17221 aacatttttt agactctatt tcagctgtaa aaaatggata tataaaaaat gggatgtcta
    17281 taatagatgt tggtacaggt gctggttttc ctggaatacc attgaaaata tgtttagata
    17341 gcttagaact tactttgtta gattcgttaa ataaaagaat aaacttttta gaggaagtta
    17401 gtagagtact agagttagat aatattacat ttatacatgg aagagctgaa gattttggta
    17461 aaaatgaaga ctatagggaa aaatatgatg ttgctacggc aagagctgtt gctggattac
    17521 cgattcttat ggaattttgt gtaccatttg taaaagttgg agggtatttt atttgcttaa
    17581 aaggtccgaa tgctaattta gagctagaag aatcacaaaa ggctattgat gttttaggat
    17641 tggagtatat tgaaaaaata gatgtagagt taccagaggt agatttaaat cataatatat
    17701 tagtttttaa aaaagtgatg gaaacaccag ttaagtaccc tagaaaagct ggtaaaccag
    17761 ccaaaaatcc tattaagtaa tgaaaaattt attattggta agcttaatta tttctcagga
    17821 aataattaag cttactgtaa aaaaacaaaa ataaaggaat tattaaagta gatgcagaaa
    17881 taaatttgta tgtacatata gagaacaaaa ataatttata tctaaaataa gagaggtatg
    17941 ttatggaaga taaaagagtt atggagatac ctatagaaga tgtagttcca aatccatatc
    18001 aaccaagaaa aatattttca caagtttcat tggaggaatt gagcaattct ataaaggtat
    18061 atggtataat tcaacctata acagttagag caaaagatgg caaatatgaa ctaattgcag
    18121 gagaaagaag attaagagca gctaaattag cagagcttaa aaccatacca gcaattataa
    18181 ataatatgaa cgatgaatct tctgctgttc tagcgttatt agaaaatttg caacgagaag
    18241 acttaaattt cattgaagaa gcaattggtt atgaaaactt aataaaagaa catgctttta
    18301 ctcaacagca attagcagaa aaattgggca aaaatcaatc tactgtagca aataagctta
    18361 gaatattaaa gcttccaaac gatataaaaa tgaagctaat agagaataat ttaacagaaa
    18421 gacatgctag agcatttctt aaactaccaa gtgaagattt aatgcaaagt gtgttagaca
    18481 aagtcataaa aaatgaattg actgttaaaa aaacagaaaa attgatacaa gatgtattag
    18541 aagaaactaa agttcaagaa gagcctgata aaaaacagaa tataaagggt gctatgagta
    18601 taagaattta cataaatact ataaagcagg cctttgatgc tatatcaaat acaggaattg
    18661 atgctaagta taatgaaata gataagggag attatatgga agttgttgta aaaatcccta
    18721 aaaaatagag attactgctt accagtaatc tttttttgta atataagcct tgtaatataa
    18781 attgatttat agacattatt tatacttaaa aaacacctat tcaacattta aaattaattt
    18841 aattcttaaa ggggggaaca tcatgggcaa agttatagct gtattcaatc aaaagggtgg
    18901 agtcgggaaa actacaacaa atgtaaattt aagtgctagc ttaggaactt tgggaaagaa
    18961 aatattagta ttagatttag acccacaagg aaatacaact agtggatatg gtattaataa
    19021 aaacgaagta gaaaatacaa tctatgaaat tatgttagat gggttacata ttaaagaagc
    19081 aataataagt actgaatttg agaatgtaga tgtagttcca tcagctactg aactatcagg
    19141 tgcagagata gagcttacat ctaaaactaa tagagagtat attttaaaaa attccataaa
    19201 agcggtaata gatgaatatg attatatatt tttagattgt ccaccctcac tggggatgct
    19261 tacaataaat tgtttaactg ctgtagatag tgttttaatt ccaatacaat gtgaatatta
    19321 tgctttagaa ggtgttagtc aattaatgga gactataaaa ttagtaaaat caagattaaa
    19381 tgctgatata gaaattcaag gtgttgtttt aagtatgttt gatggaagag ctaatttatc
    19441 aatacaagta gttgaagaag ttaagaaata ctttaaaggt agtgtatata caactttaat
    19501 tccaagaaat gtaagacttg cagaagctcc aagtcatgga aaacctgtaa tttattatga
    19561 taaaagatgt agagggtctg tagcttattt ggaactagca gaagaattta tagatttaga
    19621 agaggaggaa tggtagtatg gagaataagt ctaaaagaag taatagatta ggtagaggtc
    19681 ttagtgcatt gataccagaa attaaaggag aaacttcaga aaaagaaata gtcaacatag
    19741 atatagacaa aatatatcca aacgaagttc aacctagaaa gcaatttgat gaagaaaaga
    19801 taaaagtatt gtcggattct ataaaaaatt atggtgtttt acagccaata gtggttaaaa
    19861 tggatgaaaa taataaatat atgataatag ctggagaaag aagatttaga gcatcaaaac
    19921 ttgcaaataa aaatcaaata cctgctataa ttaaagatat agatatgaaa gatataatgg
    19981 agatagcctt aattgaaaac ttacagaggg aagatttaaa ttcaatagaa gaggctctag
    20041 catataagag tttaatagag cattacaatg taactcagga agaaatatca gaagctgttg
    20101 ggaagagtag acctcatata actaatacac taagactttt aaatcttgga caagatgtta
    20161 tagaaatgat agacagtggt agaattacag caggccatgg taaggcttta ttgagaattg
    20221 cagataaaga tttgcaactt caaatagcga aaaaaataga agaagaagaa ctttctgtaa
    20281 gagaagtcga aaatatagct aaaaaaatat ctgaaaataa acaagaagaa cctaaaaaat
    20341 ctaaacctaa ggatgtattt attttagatg ttgaagataa acttagaaat atatttggaa
    20401 caaaggtgaa tatttctaaa ggaaagaaaa aaggtaaaat agagatagaa tactataatg
    20461 atgatgattt aaatagtatt gtatcaatgc ttcttgaata gaacaaaaat ataaaacaga
    20521 gaggaagatt gttatgattt atttagataa tgctgcaact acatatccaa aaccagaaag
    20581 agtgtataat gctgttttag attgtatgaa aaattattgt gcaaatccag gtagagcagg
    20641 ccataaactt gctatgagag ctgctaggga gatatatgat acaagagaga atatagctaa
    20701 gttgttcaat gtaagtaatc ctatgaatat agtatttaca tctaatgcaa cagattcttt
    20761 aaatttagcg ataaaaggtg tattacaaga aggagaccat gtaataacaa cgtctatgga
    20821 gcataattca gtaataagac ctataaaagc attggaaaaa aggggtattg aaaatactgt
    20881 agtaaaatgc gattatgagg gatttttaga ttatgaagat ttagaaaaat caataaagaa
    20941 taatactaaa ttgattgtaa caacacatgc gtctaatgta tgtggaactt taatagatat
    21001 aaaaaaagtt ggagaaatag ctaaaaaaca taatatacta tttttagtag atgcatcaca
    21061 aacagcaggt gtttatgata tagacgtaaa tgaatgtaat atagatatgt tggcaatgcc
    21121 aggtcataaa tgcttatttg gacctcaagg aacaggtata ttatatgtaa gagaagggtt
    21181 gaacttaaat atattaaaag aaggtggaac aggtagtaaa tcagaagaaa tagttcaacc
    21241 agagttattc ccagataaat atgaatcagg aactcataat actccaggta tagcaggtct
    21301 taaccaaggt atactattta tatttgaaag aggaatcaac aatataagac aacatgaaga
    21361 agaattatgt caatatatga tagacaaatt agaggaagta ccagatataa agatatatgg
    21421 accaaaggac agtaaaaaaa gagcatcagt aatagctcta aatataggag atatggattc
    21481 tggagaggtt actttcttat tagatagtga ttataatata gcgactagat caggaataca
    21541 ttgttcacca ctagcacata ccactttagg tactttaaaa caaggtgcag taaggttcag
    21601 tataggatat ttcaacacaa aagatgagat agataaagca gtggaagctt tgaaaaaaat
    21661 ttcaaaaaat aaatagcatg agatttaata atatagaaat aaaaaaaggg gatatttcaa
    21721 aataaaaatt tgaatcatct ccttttttgt acaaaaaaga aaaggggttc ctaagaacct
    21781 ctaatctatt tgataatagt ttcaagaaat tactttaagt aatctccttc ttcaagaact
    21841 atatgaccac tttcgtaatt agaaccatca acagtaattt ttatttgttc aacattcata
    21901 ttttttatgt aagtacgagc aactgaatca agcattaaag tttctgcatc actacctaag
    21961 tttgactttg taaagtcaga gctaacatct aatataccag tttttacacc atcaatgtct
    22021 tttgtagtaa atgaatttaa ttttgcagat tctggaacaa ctttaagttt ttgaagttct
    22081 tcaaataaag tgttctcatc aattttattt aaatcaactt tattttcaat taaatctgtc
    22141 ttatctacat caaaagagta aatagtagct gattgagctt tagtttcttc ttttggagta
    22201 ggtttagctt tgttattagg aacctctttt tcagtattgt tttcttcttt tggttgctca
    22261 acatttgtat tgctcttagt ttctttttta gatgaatcac ttccattttg agcattagta
    22321 caaccaactg cgaatataga tatagataat atacttaaca ctaacattat tttcttattt
    22381 ttcataaaaa tttctcctct cttaaaaact attcttatat ataattatag tcgttatgag
    22441 caaatatatg aatacaaaat agtaacaaat ttaaaaaatg atttatttaa attaataaaa
    22501 ctcaaaataa actaaatttt agtcattttt atgggaaatc atttaatgta cagtgaaaat
    22561 attgtaaaat aaaagtagtg tttttaaaat aaatataagt tataattata ttataaaaaa
    22621 atgtcttcaa aaggtgggaa tagtatggaa attttgagct taggagaaaa gattaaaaag
    22681 ttaagaaaag aaaaaaacat gacattgaaa gaattagctg gagataggat aacagcagca
    22741 caaataagcc atatagagag agataaatct catactagtt atgaactgtt ggaatatcta
    22801 ggcgataagc tagatgtaag tgtagaatac ttattagaga ccaaggaaat gcaatcaaaa
    22861 aagataactg ataatttaat actacagagc gaaatttata taaaagaaaa tgaattaaac
    22921 aaggctgagg accaaataaa agaagtttta gatatatgta agagatacga tttaatggag
    22981 aactatggca gatgtaattt tttaatggct aatattaatt tgaaaaaatc taattataat
    23041 gatgctatag aaaactttga aaaggcattg tacttcttta taaaaaatag tgatagtgaa
    23101 aatatactta agtgttattt aaacataggg aaaatatata tgcaggaaga cttttataaa
    23161 ggtgctataa gccactttaa ttttgcagag gaaattttgt cagagagtaa atttgaggat
    23221 gttaacatac acaaggaact atatagtaag atggcatatt gttacataaa actagataat
    23281 ccaaatatgt cattgaagta catagaaaag ataaatgaaa tagataatag aaatgataga
    23341 aaagaagatg tcgatatttt ggtgttaaaa gcaaataata tgcttgagat tggaaaatat
    23401 gaagaatcaa gagattactt taaaaaagca ctaaaaatac ttgagagtga ggataataaa
    23461 actggattag caaatgtgta tttaacaatt tgtgatgttt acagaaaaat aggtgaaaca
    23521 gatagagtac ttgaatattc acaaaaggta tatgacataa agaaaaatga tgaagatgaa
    23581 tacatgatgt caggattatt taagataata gaagcatata tagataaaga agattatgat
    23641 ttagctagaa aatattgtaa gatagcctta gcttcatcaa taaaaaataa aaataaattc
    23701 aatgaatata aagcattgag attctatgct aatatgtata aaaatcagaa tgaagtaact
    23761 cttgcaattg aatatctgat taaatgcata aaaatagtat cagatttagg caacaataga
    23821 atattggcca atttatatat agacttaggt caattatatt caaatatatc aaaagaaaaa
    23881 gagttagaat attatcaaaa aggtgtattt atgtacaaaa atttagaaat aatgtagggt
    23941 aaataaacct ataagggtat agaaacaatc tataacaagc aagataatat ctatgataaa
    24001 atataaattg tatgaatatt tttaaggaga tgaatcagac aatgagtata aaaatagatg
    24061 cgagagggct tgcttgtcct aaaccagtta taaatacaaa aagagaattg gataacctag
    24121 aagaaggtgt tgtagttaca atagttgata atgaaacagc taaggagaat atattaaaac
    24181 ttgctaaatc tttaagttgt gaagcaaata ttgttgacga aaaagagaat tttatatcta
    24241 tagaaattag aaaaggtaaa aatatactag ataaacaaaa tgttgtagat aataaagaaa
    24301 gtgaattaga caatacatgt atatttatat cttcagataa gatgggactt ggaaatgacg
    24361 aattaggaaa agtgttaata aaaggattta tatatacatt aacagaatct aaaccttatc
    24421 ctaagtatgt acttttagtt aatggaggag taaaattaag tgctgaaaat gaagaaacca
    24481 tagaaaatct aaaaatactt gagaatatgg gtgtagaagt tttatcttgt ggtacttgtt
    24541 tagattatta taatttaaaa gacaaattac aagtaggtac agttacaaat atgtatacta
    24601 tagttgagac attaaagaat gcatcaaata ccatttctat ataatgtatg tatgtttaat
    24661 aatataaaac taacaataaa gattaactca aatagatagt cagaaaggat taagtaatga
    24721 atcaaatgta tatagtgtca tttaattcga cacatcatgc gataagatca gaaaagttat
    24781 ttggtgaaaa tagtctaaaa gtaatggctc ttccaacacc aagagaaata acagcaagtt
    24841 gtggaatatc aattaaattt tcttttgaag atatggaaaa gataaaaact attttggttg
    24901 aaaataatgt agatataaaa ggaatttatt gtataagtaa attagaaaat ggttcaaaag
    24961 aagtagagaa gttagattag gaggctaatt atttatgcca atggatttaa aaataggtga
    25021 tattgttgaa ttaaaaaagc aacatgcatg tgggtgtaaa gagtttgaaa tcataagaac
    25081 gggaatggat ataaagataa aatgtactaa atgttcaagg ctaataatgc ttgatagaga
    25141 gaccttagaa aagagagtaa aaaagctaat aaaaaagtga taaaaattta acacttaaaa
    25201 aatgtcaaat accgtatatt aatatccaaa attttggtat aataagaatt gaagaaaaca
    25261 ttttcatggg ggtgctttaa ttatggcagt taaatatgca aaaagaatgc aaggattaca
    25321 aggatcagaa atacgtgagc ttttaaaact tactcaacaa ccacaaataa tatcttttgc
    25381 tggtggaatg ccggctccag agttatttcc agttgaggaa atgaaaaaag tatcagttgc
    25441 agtgcttgaa gaaaatggaa gatcagctat gcaatatact acaacagaag gatatgaacc
    25501 attaagagaa aaaatagcag ctagaatgaa tgataaaaac aaaactaatg taaacaaaga
    25561 tgatatatta gttacaagtg gttctcaaca aggtctagat tttgcaggaa aagtatttat
    25621 tgatgagggt gatgtaattt tatgtgaaag tccatcttac ataggagcta taaacgcatt
    25681 taaatcttat caacctaaat tcatagatgt tccaacagat tctgatggaa tgataatgga
    25741 agaattagaa aagatactag aaacaactga tagaataaaa atgatttatg taatacctga
    25801 cttccaaaat ccaacaggaa gaacttggcc acttgaaaga cgtaaaaaat tcatggaaat
    25861 agtaaataaa tttgaaatac cagtaataga agataatcca tatggagatt taagatttga
    25921 aggagagact ttaccatctt taaaatcaat ggatacaaaa ggattagtaa tattcttagg
    25981 aactttctct aaaatattct gcccaggata cagattagga tggacttgtg cttctccaga
    26041 aattttatct aagtttaact ttgcaaaaca aggtgcagac ttacaagcat caactatatc
    26101 tcaaatggaa gtaagcaaat ttatggatat gtatgaccta gatgcacatg ttgacaaaat
    26161 aaaagcagtt tatgttaaac gtagagatgt aatgcttaag actatggaag aagagttccc
    26221 agaaggatta gtatttactc atccagaagg tggattattt acatgggtag agcttccaag
    26281 taatttaaat gctaaagaat taatgccaaa atgtttagat aagaatgttg cttatgttgc
    26341 tggaggagga ttcttcccta atggtggtag agaaaatact ttcagactta actattcaaa
    26401 tatgccagaa gaaaaaataa tagaaggtat aaaaaatata gcagctgtat taaaagaagc
    26461 tatgggtgta gaagcttaat taaaaataat aacttatata taatacaagg gatggttgtt
    26521 gccatccctt gtttgtttga aaagtatata attcacctta tactaaactt tgtccaaaat
    26581 ttaaattgac agaaataaga ataaatgata aaatgtgtag gtatgagatt ttagtctcat
    26641 ttctctgctc taagagtgta gagccgttaa gtccaaaggg aggtgaatta tagtgagaaa
    26701 ttatgaatta gtttatgtgg taaagccaaa ctctgatgaa gaagtaagag aggctatact
    26761 aaacaaagtt aaggaagttg ttgcaactga cggagaaata gttaaagttg atacttgggg
    26821 aactaaaaaa ttagcttatc caatagctaa gtttacagaa ggtttctatg tattagttaa
    26881 cttcaaatca gcagtagacg ttcctaaaga gatagacaga aacttaaaga taaatgaaaa
    26941 cgtaataaga cacatgatag ttgttgctta ataactggtt ttattataaa aaataggtgg
    27001 tgtttttatg aatcaagttg tattagtggg aaggttgact agagaccctg aattaagata
    27061 catcccaggt acaggaacac cagtggcatc ctttacaata gccattgata gagactatgt
    27121 aaaaaaagat ggatctaaag aaactgattt tatacctgtt gaagtaatgg gtaaatctgc
    27181 tgaattttgt gctaactaca taactaaagg tagattagta gcacttcaag gatctataag
    27241 agtagacaat tatcagacac aatcaggtga aaagagaact tttacaaaag taagtactag
    27301 atcagtacaa gctttggata gtaagaataa atcggaaaat tcatatagag agagtgctcc
    27361 agcttttgag ccaagctttg aacctcaagg tttagaccca caaggtttcc aagctataga
    27421 tgatgacgat ataccatttt aaaaaggagg gaaaaaagtc atgatgaata aaaaaagacg
    27481 taagaaaaaa agagtttgtc aattttgtgc tgacaaaaac gctaaaatag attacaaaag
    27541 tactcaaaga ttacaaaagt atataactga aagaggaaag atattaccaa gaagaatatc
    27601 tggaacttgt gctaagcatc aaagagaatt aacagttgct ataaaaagag cgagaaatat
    27661 agcactttta ccatatacat tagactaaaa aaatgagcct tgtgctcatt ttttattata
    27721 tgtatttata tatctaaatg aggcgagcta taaagctcgt ttttttgttt atatacttaa
    27781 atatattatt atttatgata taatattata tattaaggag ggttgtaaac gtgaaaatag
    27841 ataaaggttc tgagataacg agaaacataa agataataga atggatgaaa acagaaatat
    27901 taatgagtgt aagtgatttg tttaatttat tgtttaaagg ggtaaaacca ttagatgaag
    27961 caattcaaga tactttagca aatataataa tgataacata tctcttagca aagagattag
    28021 gaattagttt tagagatgtg gattataaag tcaaggaaaa aataaaaatt ggtatagatg
    28081 aggaccatag cgttgaaaga tggtatggag atttatctaa tttaaaaaaa catatggata
    28141 atagggagtg atattaaatt gaataataaa attagactat ctaaggcaat gtctataata
    28201 gttttagcta taataatcgc tttagtaata gcctatattc caatgctagg aatatttagt
    28261 atgttagcag ctgttccata tgtaattata ggtgctatta ctgatagaaa gtattctctt
    28321 atatctattt tggttacatt ttgtgtactg attctatttg cagacatttc ttatgcatta
    28381 aatatatgta taatgtattc tttaccaggt atagtaatag gaaagatgct aaagagaagc
    28441 tttgaacaag aggacagtaa taaattcgaa ccgatatatg gtggaaccat aatatttgta
    28501 ctttcaatgc ttgtatattt ttttgtatta aagacatttt taaatgtgaa tctattagat
    28561 gaagtttcta agatgatatc agaaattgta aatattcaaa aaaatagttt ttctgcaact
    28621 gaacttaaag tgtttgataa aatgaagcca gatgagattg taagttattt tacaaatatg
    28681 ctaccaatga tgttattttt acaagggttg ttatcagcgt ttgtcacata ttatttgagt
    28741 gtatttttta taaaaaggat tacaaagatg aatataagat ttcctaagtt tgctgatttt
    28801 tatttaccgg gaaatgctat actcacaact ttcttacttt atttattagt cttatttatt
    28861 caaattattg gttcaaaatt atatacagaa ttaataatga ctaatttaca gctagttttt
    28921 aatttaatgt ttgtaattca aggtatagca gtttgcattt atttcttaaa gaaatggata
    28981 agacagggac caaataaaat tatgtttttt tcagggataa ttttatgttt atttggattt
    29041 atgggaatat cttttgttgg tatggtagat agtataattg actttagaaa ggtaagaagc
    29101 tataaatcca cttaggagga tagaaatgag taataaacaa acctttaaat taaatatgcc
    29161 agaaataaat ttatatataa ttgttattgg tatttctagt ataattttgc tttattacaa
    29221 cttgtatgta gggtgtttat ttttctgtat ttttgtatat atggtttttc acaattggag
    29281 aactactaat attagacgtc atgaatggac agagtatatt caaaatttat ctttagatat
    29341 agatgaaaca actaaaaaag ccataataaa tcttccaata ccattatgta ttttagaatt
    29401 tgatggaaat atatcctggt ataatggaaa gttttatgat atgattggtc aaaaagattt
    29461 acttgataaa aatatagagg atatagttaa aaatcttaat ttaagaaaag tattaaatga
    29521 aaataaagag atgtacacag aaataaacta taaagaaaaa gaatatacaa taatttataa
    29581 tgttataaaa aatgatcaag aaaaaaatcc taaatatttg atgatattat actggataga
    29641 caagactgaa tatttaaaag taaaacaaaa ttatgatgat gaaaaaaatg caatgatgct
    29701 aatacaagta gatggatatg atgaagtatt aaaaagtgca gcagaagata agagagcttt
    29761 aattaatgtt gaagtagaga aaatactttc tgctttagaa ttaaattcaa atggtgcatt
    29821 gagaagaact tcaaaagaca aattcttctt ggtaatgcat aaaaaagagt taaaaaaatt
    29881 ggaagctgag aagttttcta ttttagatac aataagacat attgattatg gaaataatct
    29941 tcctgttact ataagtatag gaattggtat agatggagat acattaaatg agaacctaaa
    30001 acttgctacg ggtgctctcg atttagcact tggtagaggt ggtgaccagg ctgttgtaaa
    30061 aacaaaagat aaatttgtgt tttatggagg aaaatctaaa gctgtagaaa agaaaaccaa
    30121 agtaaaatcc agattaatag gtcatgcttt aagagaggtt atacaacaaa gtgaccaagt
    30181 ttatataatg ggacataaat atcctgatat ggatgctatg ggagcagcag ttggtgttta
    30241 tgatatatgt aaatcctgta acaaaactgc aaacatagtt ttacaatctg taaatgaatc
    30301 tatagaaata tttataaata aaataaatga aaataattac tataaaaagt tgtttattgg
    30361 aaaagaggaa gctattgaca actgcactaa aaatacatta gttgtagtag ttgatactca
    30421 tagaccaaat tatactgaat gtgaagaact gttaaagcta tcagagaagg tagtagttat
    30481 agaccatcat agaagaggtg tagagtttat aaatgatgca gtgcttttat tccatgagat
    30541 atatgtatcc tcaacgtgtg aaatggttac agagttagtt cagtatatgg atgaagatgt
    30601 aacaataaat aaacttacag ctgaagggct tttagcaggt ataagtctag atactaaaaa
    30661 ctttgcattc aaaacaggtg ttagaacttt tgaagctgct tcttacctta gaaaagttgg
    30721 agcagatact atagaggtaa agaaattctt caattctgat gtaaaagatt tcataataaa
    30781 agctgaaata attcaaagta ctaaaataat taataataga atatgtttag catattcaag
    30841 tactgagata gatagtataa atgttataat agctcaaact gctgatgagt tattaaatat
    30901 caaagaagta gaagcttcct ttgtattagg tgaaaaagat gatactatat ttataagtgc
    30961 gaggtcttta ggacaaataa atgtacatgt acttatggaa aaattaggag gcgggggaca
    31021 catagatata gctggagcac agttaaaaaa tgtttctcta aaagaagctt ataagatggt
    31081 aaataaaata atagaggagt atttggagga ggaagaatag atgaaagtta tattattaaa
    31141 agacgtaaaa ggaactggta aaaagggaga aatgaaagaa gtaagtgatg gatatgcaag
    31201 aaatttctta tttcctaaaa agatggctgt gcaagcagat agtgtagcaa taaaagaatt
    31261 aaatgaaaag aataaatcta aagaaataaa agcacaaaaa gagtatgaag aagcagtttt
    31321 attaggtaag caaatggaag aaattaatat agaaatatat tcaaaagcag gagaaggtgg
    31381 aagattattt ggttcaataa cttctaaaga aattgctgag caattaaaga aacaaaaaga
    31441 catagatgta gataaaagaa aaatattatt agatgaacca ataagatctt taggttcaac
    31501 tttcgtagaa ataaaaatac atcaaaaagt aactactaaa ataagagtgg atgtaaaaga
    31561 aaaacagtaa taactagagg tgattaagat ggaagatatg acgagaattc ctcctcatag
    31621 tgtagaatca gaacaatcaa tattgggttc tatacttcta gataaagatg ctataataac
    31681 ggttacagaa actataaagc ctgatgattt ctataaagag gctcacaaaa taatatatga
    31741 atgtatgata actttaagta ataaaggtga gcctatagac ttgataacat taacagaaga
    31801 actaagaaaa caagggcatc ttaatgatat tggaggaatc agttatatta caagtctttc
    31861 tactatagta ccgacgactt caaatgtaaa atactatgct gatatagtaa aagaaaagtc
    31921 tgtacttaga aagcttataa aagcttctaa tgaaataata aatctaggat atagtggagc
    31981 aactaagatt gaagatgttt tagaacaagc tgaaaagagt atatttgata tatcacagga
    32041 gaaaactagt gatgatttta aatctataaa cttagttttg atggatgcct atgatatgat
    32101 agaaaaatta tacactaaca agagtgatgt cactggtata actactggtt ttaaagattt
    32161 aaacaaaaaa ataaatggtc ttcaaaggac tgatttaata ttaattgcag ctagaccagc
    32221 aatgggtaaa actgcctttt ctttaaactt ggttcaaaat gcagccttaa aaggtgatgc
    32281 ctctgtagct gtatttagtt tagagatgtc taaggaacaa ttagtacaac gtatgttatc
    32341 ttcacaatct agtgtagaat taaaaaaaat aaagactgga acacttaatg ataatgattg
    32401 gcctagaatt atagatgcta tggcagtatt atcagatgcc aaaatacaca tagatgatac
    32461 tcctggtata aaaatatcag aactaaggtc aaagtgtaga aagttaaaaa tagaaaaagg
    32521 actagattta gtgcttattg attatcttca acttatggaa ggtgaaggta ataatgaaag
    32581 cagacaacaa gagatatcta agatatcaag gtcactaaaa atattagcaa aagaattaaa
    32641 ctgtcctgta gtagcactat ctcagttatc acgtgcacca gaacaaagag cagaccatag
    32701 acctatgtta tctgatttaa gagagtctgg agcaatagaa caggatgcag atatagttat
    32761 gttcttatac agggacgaat attatcatgc tgattctgag agtaaaaata taggagaagt
    32821 aataatagca aaaaatagac acggtgaaac tggttctgtg gaacttgttt ggcttggtga
    32881 agttcaaaga tttggggata agttgagaga cctataatct aacgaatatc cacagaacgt
    32941 cctttctttc tacaggaaaa atgtggatac atgtcactaa atatgtccaa acattgaaat
    33001 ttagctaaaa aactatccac actatccaca gatggcctgt tgataagtgt gaataagtag
    33061 ataaagcaag cttttggctt gctttatctg tgtataaata ttaattatta ggaggaataa
    33121 tatggaaaaa ataagcttaa aatatatata tcccaatata attaaagtac ttgatgaaat
    33181 aaacttattt agagtaattg acaataattt aagagaatct attgttgttt atgctaataa
    33241 tgtggataat cagtatcata taaacatgac taatacaaac tttggaaata taattaacat
    33301 atgtaaatta gaaaaacttt tagatgtgga taaatttatg gaaaaagtta taaaatatga
    33361 aaaagaaata atagagaaag aagagttttc aaaaatagaa gaatatatgt taaatattgg
    33421 agaatactaa aaaagttgaa aaaaatacga atgtttgata gaataagtaa gtaaagtgtt
    33481 cgagagtata taaaatatag aggtgaatta catgaaaaca gttgcaattg ttggttctca
    33541 atggggagat gaaggtaaag gtaaagttat agattatctt gctactcaag cagatgtagt
    33601 agtaagaggg caaggtggaa ataatgcagg acatacatta gttgtagaag gtaaaaaata
    33661 cgcattacat ctaattccat ctggagtttt aaatccaaat acagtgaata taatcggaaa
    33721 tggaatagtg tttgacccta aaggattttt agaagaattg gaaatgttta aaacggataa
    33781 tataagtaca gaaaatataa aaataagtga tagagcacat gtcatattcc catatcataa
    33841 agaactagat gcattgtcag aagaagccag aggcgattta aagataggta caacaaaaaa
    33901 aggtattgga ccttgttata tggataaaac agagagatct ggtattagaa tatgtgactt
    33961 aatggataaa gataaatttg ctataaaatt aaaagctcaa atagatgcta aaaatgaaat
    34021 agttaaaaat atatatggaa aagaagaatt atttgatttt gaaactatat ataacgaata
    34081 tctaggatat gcagagcaaa taagaaaata tgtggcagat acgtctgtta ttgtatatga
    34141 tgcagtaaga gcaggtaaaa aagtattgtt tgaaggagca caagggactt tattagattt
    34201 agatttagga acttatccat ttgttacatc ttctcatcca acatctggtg gatttgcaat
    34261 tggtgcaggt atagggccaa atatgataaa agacgttgtt ggtatagtaa aagcatatac
    34321 tacaagagtt ggagaaggac cgtttgttac agagcaaata aatgaaactg gagataagat
    34381 aagagaacaa ggacatgaat ttggggtaac tactggtaga ccaagaagat gtgggtggtt
    34441 tgatgcagtt atagttaagt atgcagctag agttaatgga ttgactagta tttcatttat
    34501 gttacttgat gtattaactg gatttgataa gataaaagtt tgtacgtctt ataaaatggg
    34561 cgataagata ataacggatt tcccagcttc attagatgat ttagcaaaat gtgaacctgt
    34621 atatgaagaa ttagatggat ggaatgaaga tataactcaa atagataact ttgatgacct
    34681 tccagaaaat gcaaagaaat atgtagcaaa aatagaagaa ctagttggag taagtgtaga
    34741 tatggtttct gttggtccaa atagagctca aactataata agaagaaata tatttgctta
    34801 atattttatc aattaaataa tttaaaatag ttgaagaaga gtatctcaag ataatgttta
    34861 tagttattag agatgctctt ttatatttga cttacattga ttttttatta agttaaagct
    34921 acttatacat attctaactg aaattaaagt tgaatttatg tagatacata taggtttttt
    34981 aaaaagaatt ttgttgaaaa taaatggcta aagatgattt taattatatt ctaaaaaaag
    35041 taaaaaaaac tattgactaa aaattatata gacgctataa tataacttgt gagtgaaaga
    35101 aacgacgaaa aaagtcgaaa aaatgtggtc tattagctca gtcggtagag cacctgactt
    35161 ttaatcaggg tgtcccgcgt tcgagtcgcg gatagatcac caaaatatgg ctcgttggtc
    35221 aagaggttaa gacaccgccc tttcacggcg gtaacagggg ttcaattccc ctacgagtca
    35281 ccagtatggg actatagctc agctgggaga gcacctgcct tacaagcagg gggtcacagg
    35341 ttcgagccct gttagtccca ccaaattttg aattagagat aaatactaga ttatatgctg
    35401 gtgtggctca acggtagagc agctgacttg taatcagcag gttgtaggtt cgattcctat
    35461 caccagctcc acaaagtaca taaattcaaa ttaatataat tttctatgtt acaggatact
    35521 tttaagtatc tttttttaat ttcattttta ttgtattaaa aatgaaatta aacatacaac
    35581 aaaattttga attacttgca atgtgatagt tttaaatata aaatttagaa tcattctagc
    35641 ataatattat gtaatatagc aaatttaatt tatagtatca ataaatatag actactaaga
    35701 atgtaaatga tttgttagat taaggtacat tagatatgta aatagaaaaa taaaaagtat
    35761 gttttaattt atgtgatata agttttaaac agagaagcaa gtttgctctt acctctctat
    35821 ttaaaaataa aaaaatgttt tttaagggct attttattta aatctttccc atctcaaatc
    35881 atctccagta aattctaaaa tcctaaactt atctaatatt ctagagagag ttctttgagt
    35941 gtaagtattt cctatttgag atggtgttaa gttggttgaa ataatgattt ttttaccagc
    36001 aacaagtctt gtatttacaa tattgaagat ttctccacta gtaaaagaat tattaagttc
    36061 agttccaagg tcatctatta ttaataaatc acaatcaaac aagtttttat aattatcttc
    36121 acttatttga ttatttgtgt ctcttctaaa tttataatct tcaagaatat ctaaaattct
    36181 aaaagaagtt tgatagatta caacattgcc tttatctaac aattcctttg caatacaatt
    36241 gcacatatag gtctttccta gtccagtaga accataaaac agtagatttt cactattatc
    36301 cttcttaaaa tcatgaacaa aattttcgca gatacttaaa ttatttagca tattttctct
    36361 aggagatatt tcaccatcag agcctttctt aggagaaaat atattcaagt taaaattcga
    36421 aaaattttcc tgacttaaaa tcctatctaa attagacatt ttataagctt catttacaat
    36481 ttcttgtttg aggcaagaac atttttctcc attaggtaaa aatcctttat ctttacaaga
    36541 aatacattga aactttattt ccaagtaatc aagaggtatg ttactttcag ctaaaagtct
    36601 ttctttcttt acttttaaag attctatatt ctctttagtc ttctttacaa tttcatcttt
    36661 agacttagga tttaaaagta ctatcttagc taaactgaga cctattttag aaatttcatc
    36721 atctatagat tttatctcag ggattctatt atatacctca ttttttctat gttctaataa
    36781 gagttcatta tcatctcttc tcttagcata tttagcaagt atttttctta ttttatcctc
    36841 attcatttaa tcacctactt aaacttttct ttttgacttt ttttaataat ctcatcgagc
    36901 tcatcagagg tatactgagt gaatgtttcg ttgaaattat gaaacttagt ttttttgtaa
    36961 gtattgttgt tttgagtagt attaatctgc ttcttattaa tattctcctt aactatacgt
    37021 tcttcctctt tttgctttaa atcatttaaa ttttttatat ttttttcatt ccaattttta
    37081 attataccat ttatataaga tatacttggg tttgaaatat tcttagactt agaacatgca
    37141 tttattatca aatctatatc catattaaat ttatcaaacc aggtgtccat aagttctttt
    37201 tctgattttg atggttgtct tgaaaatccc aattcattga aaatcgtttt atataaaata
    37261 tatcgttcac ttcttaccaa aaagctttct tcaacatctt ttggcgtata taaatttgaa
    37321 tcataccaat ttctaataat gccttcaatg tatttaactg gctttgatgt accagtttta
    37381 tctttgacgt attcatatgc gcaaagtatc atatcggggc tcatattgta tttattcatt
    37441 atatccataa tactcatctt ttcacttggg tcgagatatc gcccaactat tttatttata
    37501 gaattaaaca tttttctaat acttggattt tcagaagtag atacaacttt atctgtatta
    37561 gattttatag atgaattatt gcttaatata ttctcaatat agaaattttt taaatctaaa
    37621 aattctattg aataattaaa attatcatat tcttcattgt catgtatttt tataatcttc
    37681 ttttcttccc agaatttcca agcagataac acatcagaca atggtatatt taggtttttg
    37741 gctattgaat tattgtcgaa cttaggatta gaagtaatat cacatgcttg tctatatcct
    37801 aaaagataaa cttttacgta taacccgtcc gccattggca taaatatatc tataaagata
    37861 ttgggaatag tgatttcacc taaatctatt tcattgcttt ctttaaaaaa cattttatca
    37921 cctcagatta aattatatca ttttttatat tatatttgtc tgtaaacaaa taaaaggtca
    37981 caagattagc atgtaaatat tttctaaaag tattcatttt gaaaaggagg agatattttg
    38041 gttataaaat tcaaccaaaa agtaagaaga acattatcag tagcgattct atttatggta
    38101 ttaataatag gttgctttat agaaaaggat gacagtttag aaacatacaa agaaaaaact
    38161 aattcaaaaa taaatcagta taatatggat gttatatttg atgatgagac taagaggtta
    38221 atgtgcaatc agaatgttga ctacataaat aatacaaaat caaacataga taaaatatat
    38281 ttccatatat atccgaatgc tttttccaag aaagattttg ctccttttga aaaaagtgaa
    38341 atgacaaggg cttatcctaa tggatttaac gaaggatata tagatataaa gaatatatta
    38401 aataataata gtaaaatgga gtataaaatt aaaggagaca aaaatgacat attagaaata
    38461 gaattaggga aagagttaaa accaaatgaa agaatgtcat tagatataaa atataacgta
    38521 aaaataccaa attcaattgg aagatttgga tatggagaaa atactataaa tgttactaat
    38581 tggtttccta tagcttgtgt aaatgatgaa aggggatgga atttaaagag ttatgaaact
    38641 attggcgacc cattttatag tgagactagc gattttcatg tgaaactatt gattccaaat
    38701 aaatataaaa ttgctcatac aggaaaactt attgatgata aacatgataa taagaaaatg
    38761 ctatatgaaa tagaagctga aaacgttaga gattttgcat ttatactaag tagtaaattt
    38821 gatgtaaaca aagtagattc aaagggagta gctatcaata catataattt aaataaaaag
    38881 ctttctaaaa aagcaactga agtggcaaaa gattcaataa atatatttag tgaattattt
    38941 ggaaagtatc cttacaaaga attttctgtt gtagcaagtg acttttttat aggggggatg
    39001 gaatacccta tgcttgttat gatagaccaa agtttatata atgaaaaaaa tgaattttta
    39061 ctagaatatg ttattgccca tgagacagca catcaatggt ggtattctgc tgttggaaat
    39121 gatgaaataa gtgaaccctg gttagatgaa gcacttactg aatattctac aatagtttat
    39181 tttgaacaaa agtatggtaa agatatggca aacaagctta taaaaactat ggagatacag
    39241 acaaaaagtt atttgagtga aaatatattt aagccagcaa atgagtataa aaattctact
    39301 gaatacagct tgaatgttta tacaaaaggc gcaatagcat ttaatgaaat aagaaaagaa
    39361 gttggagata aagtattctt tgagacttta aatgagtact ataataaata taagcataaa
    39421 aatgctaatg gaagagcttt tgtggaacta tggaatagta aaggtgtaga tataaataag
    39481 attataagtg aatgtaagta aatagtgaat gtaagtaaat tttgtgcaga gtattaaatt
    39541 ttatttaata ctctgttttt ttggtataat ataatttata aggcagaaaa agaggtgaag
    39601 gaatgctaaa gtattgttca gtagggagtg gtagtagtgg taattgccac tatatagggt
    39661 ataaaaatac taatatacta gtagatgcag gattaagtgg caagagaata actacaggtc
    39721 ttaaagacat tggtgtagat gcagataaat taaaaggaat atttataaca catgagcatg
    39781 ttgaccatat aaaaggagca ggtatattat caagaaagtt tgatatacca gtatttgcta
    39841 atataaaaac atggtgttct atgaaggaca aattaggtga catcaaagat aaaaatatga
    39901 aagtatttga aaatgataaa acctactcat taggtgatat catagtaaga cctttttcaa
    39961 tagaacatga tgcgtctgac ccagttggat ataattttta tacagagagt gatgaaaaaa
    40021 tgtctatagc tactgatata ggatgtataa ctcaaaatat aaaaaaacat ctatataaat
    40081 ctaaattagt agtattggaa tcaaattatg accctaatat gcttatgatg ggttcatata
    40141 catatgcttt aaagaaaaga gtaatgtcaa gtactggtca tttatccaat gaagatgcag
    40201 ctaatttctg cgttgaactt attaatgaag gtacagaatc tatattatta gcacatttaa
    40261 gcaaagaaaa taattttcct gagttagcgt atgagacttc aaaaggagta ttagcatcaa
    40321 atgatatagt agttggacaa gatgtaaaac tagatgtact atcacgaaat gatgtttcta
    40381 atgtttatga gatgaagtag aggtgaataa ctttgctaaa gagaaatttt gaaaatgttg
    40441 aggataataa aattttatac tctataaagc agggtatgat tttagcgata cctgctatta
    40501 tgactggttc aactgctctt gtaattttga atcttccaat aaaggcttat caagaatatt
    40561 tatcaggctt gtttaatgga gaggttacaa atattcttaa ctttataaat gattctactt
    40621 taggaattat ttcattaata atattattaa caataagcta tagttatgga aaaatatatg
    40681 ggagcaagta tacagtactt gttcctatag ttgcaatgtg ctctttttta gtattttcac
    40741 atggtaatga gcttaattct tatatagaaa tatttaaaac aaagtggtta tttacatcta
    40801 taattgtttc tatgacatct tctgtattgt ttgtaaaact tacagaatct tttgttacaa
    40861 gtgtaaagtt tcatacagaa ggggctgatg cagactttaa tatggtagtt tcggctatag
    40921 ttcctttcat aatagtagta tttttgtttt ctatttttag agtggtaatg ataagtctaa
    40981 ttggcagttc aaactttcaa gatatatttt ataatttatt ttcaaatgtt tttaataaaa
    41041 tgggaacaaa ccttatgagt gctctgttgt ttattttttt aatgcacttt atgtggtttt
    41101 ttgggattca tggtagtaat gtattagata ccgtcgcaaa aaatttattt gaaaatagta
    41161 tggcaattaa cataaattta gttaataata atcaattacc aacagaaatt tttactaaga
    41221 ccttttttga tacaatggtt ttattgggag gatgtggctc tttactatgt ttagtaattg
    41281 caatttttct tagtgaaaaa cgtataaatg taagaaagtt agctaaaatt gcttcaatac
    41341 cagctctttt taatatcaat gagatgctag ttttcgggat accaattgtt tttaactata
    41401 ttatgtttgt accttttgta attactccta taatcttaac cgttacaagt tatgtggcta
    41461 tgtctacagg tattgtacca tgtacagttt cagctgtaga atggacctca cctatatttt
    41521 taagtggata tatgtctaca ggttcaataa gaggtagttt gttgcaagta tttaatttat
    41581 gtgttggtgt tatgatttat attccgttta taaaaatgtc gcaaaataga tatacatata
    41641 tgtttaaaaa taatatagaa aatttaacaa acttattaaa aaggtatgaa ttaacaggtg
    41701 aacagcctaa tcttctaaac cataatggta aaataggttc aatttcaaaa atgttggcat
    41761 cagacttgaa gtttgctatg aaaagaggag aaatagagct tttttatcaa ccacaagtca
    41821 attataatgg aaatgttgtg ggagcagagg gattacttag atggaaacat tcaataggag
    41881 ggttcattta tccaccacta gttataattt tggctaaaga agaagggttc ttagatgagc
    41941 ttggagagta tattattaat aaagcatgta ttgatttaaa gaagagtgaa aagctattga
    42001 gaaatcctgt taagttctct gtaaatatat ctccagacca acttgatgac cctaagttac
    42061 cagagcaaat aaaaaatatc attagtagta atgatataaa tcctaatatg ttaggtatag
    42121 aaataacaga gcaaattgca ttatcaggtt cacaaataat tattgaacgt atcaatgcga
    42181 tacataactt gggaataaag ttaattatgg atgattttgg gatggggcat agctctctta
    42241 tatatcttca aaataataac tttgatatag ttaaattgga tggttcatta gttaaagaga
    42301 tacttacaaa taaaagaagt agtgaaatta taatgactat tgtaaatctt tcaaaaaatt
    42361 tagattttga tatagttgtt gagtatgttg aaaatataga ccaaagggat aagttatatg
    42421 gtttaggatg tgaaatatat caaggatatt attatagcaa agcaatacct tttgaagagt
    42481 ttgtagaata tgcaaatcaa gaaagagaga tataatttta taagagcttg taaattctag
    42541 taatgcatag atttgtaata aaattaagtt taggagaaat atatgaatat aagtatagta
    42601 gtagtaggta aaattaaaga aaaatattta aaattaggta ttgatgagtt taagaaaagg
    42661 ctttctaagt attgtaagtt agaaattata gagttggatg atgaaaaagc tccagagaat
    42721 ttgagtgtta aggaaatgga aattataaaa gacaaagaag gaaagaaaat tttagggaag
    42781 ataaagcata atagttatgt tatagccttg gctattgatg gtaagggttt atcctctgaa
    42841 gagcttgcta agactatgag tgatttagca gttagaggta atagtagtct ctgttttata
    42901 ataggaggtt ctttagggct ttctgatgag gttttaggaa gggctgatta taggttatcc
    42961 ttttctaaga tgacttttcc tcatcagatg atgagattga tattgttaga acagatttat
    43021 agggcttata ggataaataa tggagaaccg tatcataaat aaatgatacg gtttttgtta
    43081 atttgacact taataatatt aaaataacaa aaaagtattg aaagtatatt gcatttaagg
    43141 tagaattaaa taaaatatta taacattata atgtttatat ggttgttaat aaaaatttgg
    43201 aggaaaatat atgataaaaa taatgttggc ctgttcagca ggaatgtcta caagtttatt
    43261 agttactaaa atggaaagtg cagctaaaga aaatggtata gagtcgcaaa tttgggcaat
    43321 accagaatca actatacaaa atgaaataga aaaatgtgat gtattattac taggaccaca
    43381 agttagatat gtattaccta aggctcaaga aattgctaag ccatataata taccagtaga
    43441 agttataaat atgatgcact atggaacagt taatggagaa gctgttttaa atagagcgat
    43501 agaacttaac aacactaagt aatataaatt ataatgtatt tttaatatat aaattgggag
    43561 aatcaaagga tggatgaaaa gactatagaa atatctttta atataatagg ttatgcaggt
    43621 gaaggtaaag gattagcttt tgaagcaata aaagaggcta agaatggaaa tatagaaaaa
    43681 gcaaaagaat tattaaaaga gtccagggaa gttataaata aagcacatag atatcaaaca
    43741 gaattaatac aaaacgaagc tagtggaaac aggactgaaa taagtgtcat acttatacat
    43801 gcacaggacc acttaatgaa tggcatgaat tttcaacagt tagctgagga aatcgttgat
    43861 ttacatttga aattacaaga taaataaaaa ttaaagataa taaattaaga gagttcttaa
    43921 aagatacatt atgtgtagca cactaattgt tagattattg attcaatatt tagtgagtaa
    43981 tacattagga ttattttgag gactcttttt atatttagtt taaagttaat aaatatttat
    44041 tattaataat ataagattat atgttataat attataacat ataatttaag aggtgaatca
    44101 tgttaagaaa tcaaccatta tatatacaag ttgtagatat attaaagcaa aaaatattaa
    44161 ataacgaata taaaattgat gaaaatattc caacagaaag ggagttagag caagagtttg
    44221 gagtcagtaa aattactatt agaaaagcta ttgagatatt agaatcagaa gggtatgtag
    44281 agaaaaaaag tggaaaaggg acaaaagtaa taagtaatag tctttttaat aagctatcaa
    44341 aagcagagtc tttttcaagt atacttttat ctaaaggtca taagttatct aaaaagacta
    44401 tttcaattga aaaaataata aatgatacaa attcacaagt atttagtata tttggagaaa
    44461 aatgtagcaa gattactaga atgtattact tagatagtaa gccatatata ttttttactc
    44521 attatattcc ttttgatgaa aatctaactg ttgaaagttt taataatgaa agttctttat
    44581 atatgtactt atataggaga aatataaata taactagatt tgaagatgaa ttttttatag
    44641 aagaatcaga actagaggta tcaaaggctc taaatctagc taaagacata ttattaggaa
    44701 gaaaaagaaa gacctatgat gagaatgata atatagttga gctatcattt gcaagatata
    44761 atacagaagt acaaaactat gtaattaaat acgaaatata ataagaatcc tgagtttatt
    44821 gaaatgataa tatgctcagg atttttgttt agttgtaaaa ataaaaaata ttataacatt
    44881 ataatgttta caactaaaca ttataatgtt ataatatttt taataaacaa gtgatattat
    44941 caattacata aaaattagtt tatgttatga aatcgttatt gcattataaa taaaggataa
    45001 tatcaataat acagggggat aactatggaa aaattcgcaa gttttttaga gcgcaagatt
    45061 atgcctgtag cagcgaagat aagtaatcag agacatatga gagctgtaag agcaggtata
    45121 atagcaacat taccactaac aatagtgggg tcatttttca caatattatt aaacatacct
    45181 attgatgctt atatggattt tatagctcca tttaaagcaa tattagatat accatttaga
    45241 tatactgtag gatttttatc tctatatgct acttttggga tagcatcatc acttgctaaa
    45301 agctacgatt tagatacaac aggtgttggt atgcttgcag ttatggcatt tttagtttct
    45361 acaatagttc caactcaagt agttgaacca gtaggtggag ttatagaagc tggtagatgg
    45421 atggatatgg caaaacttaa ttcgccatca ttatttggag ctatcgtaac atcattaatt
    45481 acagttgaaa tatatcgttt tatgaaggaa aagaatatta caattaagat gccagcagga
    45541 gttccagtag aggtttcaaa ttcatttact gcattattac cgacagcagt aattttaatg
    45601 ttattctggg taataagaca tattttagga tttgatataa gtgttgcact aagcgctatg
    45661 ttatcacctt taaaaggatt cttatcagga aatagtttag gtggtgggtt actgacagta
    45721 ttcctaataa ctttattctg ggtacttgga atacatggtc cagctataat ggggccagta
    45781 ataagaccta tatgggacat gtctatagca gaaaatataa ctgcattcac agaaggagta
    45841 tcagctcatg caatgccaaa catatttaca gaacaatttt tacagtggta tgtatggata
    45901 gggggagcag gggctactct tgcattagtt gtaatgttta tgttttctaa gtcacaatat
    45961 ctaaaaagtt taggtagatt aggattttta ccagggttat tcaacataaa tgaacctata
    46021 atatttggag caccaatagt tatgaatcca atactaggga taccatttat aattggacct
    46081 ataataatga caattctatc atatgttctt actattacag gggttatacc tatgatggta
    46141 gcaagattac catttgcaat gccagcacca atagcagcag taatgagtac taactggagt
    46201 atattagcag gtatcttagt attaatcaac tttgtgatat catttgctgt ttattatcca
    46261 ttcttcaaag tttttgaaaa acaacaatta caaagagaac aagaagaaat gagtgaaaat
    46321 ttataaaaat acatagatat agaggttttg tactatataa aatatagaaa aaacttataa
    46381 gttattaagg gtgaaggtag gaggaatgac ctttgccttt aattttatat attttaaata
    46441 atgtaatttg aggaggagaa agatggaaag aagattagga atatcagtat atccagagca
    46501 tagtaacatg gaagatgata aggcatatat aaaaatggct tcaaaatacg gatttaaaag
    46561 aatatttatg tgcatgcttt caattacaag acctaaggaa gaagttaaaa aacattttaa
    46621 agagattata acctatgcaa gagaattagg atttgaagta atccttgata tagctccaaa
    46681 catatttgat atattacaaa tatcttatga tgatttaaca ttttttagtg agttaaatgc
    46741 tagtggaata aggcttgact atggatatga tggaagtaaa gaagctatga tttctttcaa
    46801 tccatatgat ttaaaagtgg aactaaatat gagtaatgat gtagcatact tggataatat
    46861 aattacttac aagccaaatg taaataatat atatggttgt cacaattttt atcctcaaag
    46921 gggtacaggc ttgccatatg atttttttgt aagatgttca aatagattta aaaagtatgg
    46981 aataagaact gctgcttttg ttaattcaaa atatgcaaca atcggacctt ggaatataaa
    47041 tgatggactg tgtacgcttg aaatgcatag aaacttagat attgctacag caactaagca
    47101 cttattcgca acaggattga ttgacgatgt aattgtaggg aatgcatatg caagtgaaga
    47161 tgaattaaaa agaatgtctg aagtaaataa atatcaagtt gtatttaatg tagtaactga
    47221 ggaaaaaact tctgaagtag aaaagacaat aatggcaaat gagcaacact ttagaagagg
    47281 ggatataacc aaccaagtag caaggtctac agaagtaaga aaaaaatatg ctaaagaaaa
    47341 tttccctaag catgataata cgaccatctt taaaagagga gatgtagtga ttggtaatga
    47401 tgactttgga aagtataaag gggaattaca gttgatactt caagattgtg cagatgaaag
    47461 aaaaaataag gtaggtagaa taaaggaaga cgaaataatg cttttagact ttattgaacc
    47521 ttggagtaaa tttaaactta ttttagaggg agagtaaagt gaagatagac atattaataa
    47581 aaggtggaaa aacagtagat aaaagtataa ttgatatagc tatattagac gataaaataa
    47641 tagaagtaaa aaatcagata gatgattcta agtatcaggc aaatcaaatt ataaacctag
    47701 atggagaaaa atttattagt gctggttgga tagatataca tacgcattgc tacgaaagac
    47761 tagaccttta taaggattat ccagatgagg ttggaataaa aagcggtgtt actactgtag
    47821 tagatgcagg aacaacagga gctttagata taggtaaatt ttatgaagat actaaaaaat
    47881 ataaaacaaa tgtatatgct ttaataaata ttgctaagca gggaataaca tctcaagatg
    47941 aactttcaag tatgatgaat attgatgaat atgaacttaa aagagcagtt aaaaaataca
    48001 aagattttgt tgttggaatc aaagctagaa tgagtaaaag tgttgtaatt tcaaatgatg
    48061 ttgaaccttt aaaagtagct aaaagaataa aaaatgaact taatctacct atgatggttc
    48121 actttgggag ttctcctcca acgatagagg atatatttga ctatatggaa aaaggagata
    48181 tattaaccca tatatataat ggaaagccaa atggaatact tagaggcaat gaggttaaaa
    48241 aagaaatcat agaagctaga gaaagaggta taatccttga tgtaggtcat ggaaccgaaa
    48301 gttttagtat ggatattgca atgaaatcta aggatgcagg aatttttcca gacactataa
    48361 gtacagatat atatattaaa aatagaataa atggtccagt gtataatcta tctacaacaa
    48421 tggaaaagtt tatatatatg ggctattcac ttgaagatat aatagataaa gttactaaaa
    48481 atgcagcaga tgcaataagt ttaaaaaata aaggtttaat aaaagaagga tatgatgctg
    48541 atttaactat atttgatgtg gttaatgaag aaaaagaact tcaagattct ttgaataagt
    48601 cagtaatcac aagtacgtct ataaagccaa gagcagtagt agtcaatgga gaatatttaa
    48661 atataggtaa gtctatagga gagaatgagt agaagggaga aactattgta tgagtagtat
    48721 atttgaaaaa tactctgtaa gacgtgttat aaatgcttca ggcaaaatga ctatactagg
    48781 agtatcaaca gtagataagg aagttattga agcaataggt gaagggtgta aaaatttctt
    48841 tataatagaa gaacttataa ataaaacagg tgaatatata gcaaatttat tagggtgtga
    48901 aagtgcacta atagtttcta gtgcatctgc tgggattgca cagagtgtgg gagcaatgat
    48961 agcaaaagat gatatgagtc tagtttacaa tgtaaataat cctaagaaac aagttaaaag
    49021 ggaaataata attccaaagg ggcataatgt tgattatgga gttccagtag aagtaatgat
    49081 aagacttgga ggaggagaag ttgttgaggc cggctatgct aatatgtgta acaaggaaca
    49141 tataataaga gagataaatg aaaatacagc agcaattatg tatattaaat ctcatcattg
    49201 tgttcaaaag agtatgctaa gtgtattaga tgcagtacaa gttgctaaag aatataattt
    49261 acctttgata gtagatgcag cagcagaaga agatttaaat gtatattatg aattgggagc
    49321 agacctagtg atatacagtg gtgctaaggc tatagagggt cctagctcag ggttagtaat
    49381 aggtaagaaa aaatacatag ataatgtaaa gcttcaatca aagggtatag gaagagctat
    49441 gaaaatagga aaagaaaata ttgtaggtct aacatgtgca attgagagat atataagtaa
    49501 tgataaagta actttaaaag aaatggagga caagctaaat ccatttatag acaagataaa
    49561 tactataaag ggagtgagtg ctagtataac tagagattca gcaggtagag aaatacttcg
    49621 tggagaaatt gactttaatg aagatataat aaataagtca acacaacaaa ttataaatga
    49681 acttagaagt ggagagatag ctatatacac tagagactat aaggctaatg aaggcaagat
    49741 tgagattgat ataagaagtg taactggaag tgatttagat actatttata ataggataaa
    49801 aaatatagta gaaagttaga gtgtagagta agtgacatta taatgattta ataaattaaa
    49861 ttttaccaat ggaggggata aatatgaatt gtataccaca atattataaa aatagagttt
    49921 gtttaaatgt tcttgcagga agcataaaaa atgctaaaga agtatatgat gcttgtgatg
    49981 ggtatgtatt gataggagta ctatcaaaga attacagtac tgtagaagca gctattgaag
    50041 atatgaaaaa atactcaaag gaaatagata atgcaatatc tgtggggctt ggagctggag
    50101 acccaaatca gtcaaatatg gtatctcaga tttctaaaga acttcagcca caacatataa
    50161 atcaagtgtt tacaggtgtg gctacgtcta gagcattgct tggtcaaaat gatagtataa
    50221 taaatggatt agtttctcca actggtaaac caggatttgt aaaaatatcc acaggtccat
    50281 taagttcaaa agaaaaagat ggtatagttc ctatagaaac agcaatagct atgatgaaag
    50341 atatgggagg aagctcaatt aagttttttc caatgggagg gcttaaaaca aaggatgaat
    50401 atatagaagt tgcaaaagct tgtgcaaagc ataattttta tttagaacca acagggggta
    50461 tagacttaga taacttcaaa gagatagttc aaattgcact tgatgctggt gtagaaaaag
    50521 ttatacctca tgtttataca tcaataattg ataaagaaac aggtgaaacg aaagtggaag
    50581 atataggagt actttataaa ataatgaaag aattattggg atagatttat gaatatatta
    50641 gcttttggtg aaataatgat gagactttca gtacctgact acaagttctt aacacaaacc
    50701 aatgaactaa attatataat tacaggcaca ggattaaata tattatctgg acttaaaaac
    50761 tttggataca atacctatat gttgacaaag ttgcctaata ataatgtagg taaagcatca
    50821 agtgcaaata taagaaagct tggagtaaaa gatgacttta tcacatatgg agggaatcat
    50881 ataggagtgt attttcttga aaatgggtat ggagaaagac cttctgaagt gacttatttg
    50941 aataggttaa atagttcatt ttgtgagagt aaattacaag attatgatat tgataaatgt
    51001 ttagaagaaa tggatatagt ccttatttgt ggtattgcta tgcaacttac agattcaatt
    51061 aaagagattg ctttagaact agctagaaaa tcttatgaaa aggggataaa agtattcttt
    51121 gattttaatt ttagacaatc attaaatcca gaaaggactt atgatgattt agtaaatgat
    51181 tataagaaaa tactaccata ttgtcatggt ctatttgcta gttatagaga tataaataag
    51241 atacttaata tagatagtct aaatataaaa tctagttcag aattgattaa aaaagagtat
    51301 gatataggta ttgtagctgg aactatgaga agatttgatg atatgaataa tagatttata
    51361 aagggatata tatcaaatga tgatggttat tttgaaagta gggagtataa gttagaaata
    51421 tatgacaggg ttggtgccgg agatggatat gtagcaggaa ttatatattc atatttggaa
    51481 aatatgaaga gtgaagatat agttgagttt ggggttgcta gttcggtgtt agctcataca
    51541 acttatgggg ataattcttt agtaagcaca ggtcatgtac ttagacttat gaacaatgaa
    51601 aaaatagata tattgagata atacatttgt atataataaa atttttatct tttttagaca
    51661 cacttttgac ttgtttatat ttgttaaaca gagttatttt taatgattat aaatattaaa
    51721 ttaaaagtta aataataaaa tagtagaaaa tagcattaac tatagaaaaa atggttaatg
    51781 ctatttttat cgttaatatt gattaatttt atattataga aatgaacttt tctaatgctg
    51841 gatttgtatt ttttttattc catacaacta caacttcaat tctattttct acttctttta
    51901 taggtactat tgcaatatca cgttctatca ttgtatctgt aacacaaaat gaaggtaaaa
    51961 tggatattcc catgttagaa gataccaatg attcaatagt attaagatta tttgaacgtt
    52021 gtaccacatt aggtacaaac cctgcttcac gatatctatt ctgtatcatt gacttttgtc
    52081 catactcatc ccctgtttct tttacaaaaa taaatttatc atgttgtaat tcaattaaat
    52141 cgatagaatc ctcattgtaa agtggatgac caggaggtaa aagagctacc aaagaatatc
    52201 tttctacagt tttatattca aaatctttta atggttgatt ttctggatta ataacaaaag
    52261 cgaggtccat agaattattt tttactaagt ttaaaagttc ggttatttca ttagtacaaa
    52321 tatccataga tatattaggg tatgtattag aaaattcttt taaatattgt tgaagtttgt
    52381 ttttttcata tcctattaag gttccaatgc tcaaagttcc aaaaaaacca tgtgcaaatt
    52441 gttgtgtttt tgcaatagca tcattgatat tttttattat agtacgtgcc tcagataaaa
    52501 aaacttttcc agctggtgtt agttcaacat gacgtttact tcttgtaaat agagttacat
    52561 ttatttgttc ttctaaagct tttatttgct gtgtaacagc agtttgagaa atataaaatt
    52621 tttctgctgt tttggtaaaa cttaaatttt ctgctacaga tataaaatat tctaattgtt
    52681 tagtattcaa ataatcaccc ctatttaaac ttgattgttt gtaaacctta tttatctata
    52741 attaaagctt attatagtat aagaaaattt acttttaaag aatattagaa aatatttgta
    52801 taaaaatata tgttttaagt atatctttac attagatttt ataaatttat taataagaat
    52861 aacttatata ttccaatgaa aacgatattg gatttaagta agtttgtctc ataaaatgaa
    52921 agtatatcaa ttgataatac tttaaataag aagggagaaa aaatggaaga taaattttat
    52981 gcaaaaggca acggaaataa cggatatatt aaaaatcttg aagtttgttc ctttaataac
    53041 ttagatggaa cttgtggaat gtttcaaatg gctctgtaca aaagagatga aaaatactat
    53101 ttatatggat gctgttttgg aggaaataaa aaaaatggag taatgattag cgatattaca
    53161 gacccttata atccacaatt tataaaacat tttcaaatgt tagaccctaa agagtatcct
    53221 acaacaacaa ctcccaaaat tcaaatagca gatgatttaa tgatagtagc aatgagttgt
    53281 ggaagtggac caggagcact tgttgaccaa gctaaattag caaatattaa gtgtgaagca
    53341 ggaattagaa tatatagttt aaaagaagac cctttaaatc ctaagttttt aggatattgg
    53401 gattgtggct taaagcatgt aatgggtgtt catagattca tgtacaatgg tggaagatat
    53461 gtacatttat caagtgattg tgttggcttt gaaggtctga tttatagggt catagatata
    53521 ataaatccta ctaatccagt ggaaataggt aaatggtgga gaccagacca atatgcagat
    53581 ggatatccaa atagaacttt tgatgcagga gcacctcatt gcccagaatt tatggataaa
    53641 ggatggcttc atggacctcc atttgtaaga gacggaaaag catattgtgg ttatggagga
    53701 gctggtttag ttgtattaga tgttgaagat ttaacaagac caagatgctt aggtgaattg
    53761 ccatttatgc ctgcattttc tagtagactt gcaggtgcaa gaactcatac agcattacca
    53821 ttgccaggaa gagatttagt cgttgttcaa aatgagggag aaagattcca gttctttaaa
    53881 ccagataaca ttacagatgt tcaagctatg aataatatac atatggttga tgttagtgac
    53941 ccaacaaaac caacattaat tgctcaattt ccatatcctg aagttccaaa agatttccct
    54001 tatcctaact ttaatgttgc aggattagga aaaccagggc catttggtcc acataatctt
    54061 catgaaccaa tggataataa accatggtta gagcaaagag gagatagagt atattgctgt
    54121 tatttccatg cagggctaag ggtttatgat gtatcagacc catattatat caaagagcta
    54181 gcatatttta taccaccaaa tccaaataaa acaccagaag aatcttattt cccaggattc
    54241 ccaggaccac gcttggcagt aacagaagat cttatcgttg atgatagagg ctacatcatc
    54301 atagatgctt tagatgatgg attctatata ttaaaaatga aagaagatta aataaatact
    54361 aaagagggag agttgaaaat gaaaatacta ggtatttctt ttggaacaaa aaatggaaat
    54421 aatgacacaa tgtgtaaagt tgcacttaaa ggtgccaaag aagcaggggc tgaagtagaa
    54481 tttattcaaa tgtcatctat taacattaaa cattgtactg gatgttgtgc gtgtgttaaa
    54541 actttattat ctgggaaagg tagtatgtgt gtattaaaag atgattttga atggttgctt
    54601 gacaaaatga aagatgcaga tggtatagta gtttcagacc ctatttttga agaaggggca
    54661 tcaggattat tccatactat aatggaccgt tttggaccca gagcagatag aggaaataac
    54721 attataggaa caaaagttgc agaagctata ggaggaaaaa ttccagattc aagaatgctt
    54781 aatgataaag taatatcatt tatgggaata ggaggttctg actggggtac aagagttcaa
    54841 tgtgaacatg ctatgctagc tctcatacca atgtggaaag ttatagataa tgcttggttc
    54901 ccatgggcaa aggaattagt aatggatgat acaaggcttg ttcaagttca tcaaattggt
    54961 ttaaatatag ttgaagcagc aaaagatttt gaaaaagctt catatcaagg agaagaaggt
    55021 gtatgtccac attgccacaa tagattattc taccttgagc caggtactaa aaaggcaatt
    55081 tgtgctctat gtggtatagt tggagagtta gatactataa gtggaaaaac tatatttagt
    55141 tttccagaag agcaattagg tcatgctcat gatactttac caggtaagtt tatacatggt
    55201 gatgatatta agaaaatgga aggtcattat gcagaagttc gtaaaacaca agaatttaaa
    55261 gaaagaaaaa catcttataa ttttatagag acattaacta aagaaaaaca agctggagtt
    55321 tcattaggat aataattaaa atactaagac tcttttttaa gggatgttag atgttatagg
    55381 aggcttattg tatgaatgaa aagccaagtt ttaaacaaat tgaagttatt ttagcagtta
    55441 tttttttggt acttacatat tacaaggtta gattaactcc agcatttatt gttatattta
    55501 taccactata tttaagttat tttgcagtat ctatgattgt aaatcaaata gcaattaagc
    55561 tattggagat aaggcaagct agggaagcta ctaattacaa tataggaaat ggatagaaag
    55621 aaaaaagaaa tattaacact gtctatgggg attgctttac tacctccttt atgggcagta
    55681 ttagcacctt atataggaat aaaaactgga gctgtagcac taatctgtgc aggattatat
    55741 gtaactaatg gtaataaaca agaagatgga ttaaaaataa tgtttggttt ttggtgtgga
    55801 gatttatggg cagtgttagc cattttaatt atgggatata tgaatttcaa tcaaaaccta
    55861 gaattatttt taacacttag tatattaggt ttttttgcag ttgtaattgc atccttattt
    55921 gaaaaaataa ttttcctacc atcatggctt tgtggttggg ctataggtct aactattatg
    55981 acaggtgaaa atattattaa tttacaagat atttgtattc aaattgctgt agctatggca
    56041 gtaggagtat ggtacgtggg tgcaggtgta gatttgttta caatatatat tttgagtaaa
    56101 gataggaaaa agggaaattg aaagcatgtg aatatacttt gattatagga ggatggctat
    56161 gggttttgaa tttaaaataa tgagaagttt aatatatgta ggacttgcca aggaagaata
    56221 tagacctaag ctaatggact ggttatatcg tcaccatatt ccagatagta ttagcacttt
    56281 tggaccatat tgtactaaat atgcctttta tcaagcatat cctacaccaa atgaaggtga
    56341 gcgttttggt gcacgtaaga tgcaactaac agaacattat tggcttgtag atgaacatat
    56401 gcctgagatg gcaaatagaa ttatgacaga atatatgcct atggatgttc tacgttggca
    56461 agggtgtata ccagatgtag aaaataaaag ggttcatgaa aatgcagaaa gtggagatgc
    56521 aggacgtgca gtaggtggag ataatggatg tccaccattt atatttgcct ttgttccaat
    56581 aaactgggaa gaagacttta gaggaaaagg acgtactgta caagatggac caaactatcg
    56641 ttggcaattt atgattaagt atccagatgg tatctctaaa gaagaaggag aaaaatggtt
    56701 ctatgatgag gtagtgccat actttacaaa ctgttgctat gttaatcgtt ttgtcagtag
    56761 taaaataatg attaattatg gagcaactgc ttttgaccgt gtgtcagaac tatggtttga
    56821 aggggaagaa gaatggtata aagctgtggt tgaagagaca aagtcgttta ttaaaaaacc
    56881 agaatgggca caagaagagg agttcccata tttaaaacca caattcaata tcgcatcagt
    56941 attcttaggt gatatagcaa ctatggatgc atactcacag tatcgtggat atataccaat
    57001 gagataaaaa ttatagtttg tgataagtag agaaggcatt tactcttact ggtagaagaa
    57061 gacttattgt atccttaaaa gtaggtgaat atatagtttt atatttaaat ttatataaaa
    57121 ctaagactaa taaatatgaa acaatagaat tagaataatt tgataatatt tgttaaaaga
    57181 gcatttagaa tgtgtttaaa gattaagata ttccttttat ggtagcagat agttgaaata
    57241 ataaaactgt tatcatgaaa ggaatatttt tatgtatagg aaatttttaa aaataaaagt
    57301 taaatatgtt taagaacatc ttaaagtgaa agaatcattg ttagaaatat gtagacaata
    57361 tagtatttat aacgtatcat attaacaagt ttacacttgg attatgaaat aaaaagagta
    57421 attctaaagg ttgtaaatac tatgctgact ttgatacttc aaagtttagg tgattttgta
    57481 attgttaata gaaatacgtt taatgagcat aaagaattta tctaataata ggagaatata
    57541 atgtatacaa ttggacaagt atctaaattt ttaggaatat ctagagatac actaaaattt
    57601 tatgaagaca aaggattagt aaatcctaag aaaaatgatg aaaatggata tagaatatat
    57661 aatcaggttg atatctatga tattgcaaca ataaactttt atagagaaat tgatatagaa
    57721 attaaaaaga ttcaagaaat aagaaaaagt aaaagtataa acaatttaga actcttacta
    57781 gaagagaagg aacaaatcat actaaaagag atagaatata aaaagcttct cttaaaaaag
    57841 gttcagttag tcaaagaaga ttgtgacaaa atcaaaacat attttggaaa atacacaata
    57901 aaagaaatga agcctttgga agtaaaaggt aaaataaaac atgttactaa ctatgaggaa
    57961 tatgaagcct taaaagagaa tacaaacaac ttaaaaaaag cagttacatt aactgattta
    58021 agaagagtaa taaattttaa tgaagaaggt ataatagaag aaaaatttat aattgtaagg
    58081 gaagtagatg actacaacaa aatcatagaa ggtgaagttc tatctcatcc caattgtatt
    58141 tatactatta ttgaagatgg cagatggtca actggaggag aaaatattga taataaagtg
    58201 gaagacagat taagagaaat agcaatagaa aatgaatgtg aattacttgg aatagtctat
    58261 gttaatatat tgcttactac ttatgaagaa gggattgagc gtatattttt agagatttat
    58321 gcacctataa aataatataa aagcattgac ctgggactta ctcataggtt taaactcatg
    58381 atataagcag ttataactta tatagcaatt aaatattaat ttgaaatgag gattacttat
    58441 gagaacagag aaatcattaa aaaggcctat agccagtttt attattctaa caaatataat
    58501 ttttttacca ctttttttat tggtagtagt gactataatg ttaaaacttc caacagtgat
    58561 atctgacatt gcgttgtgta tatcagcgtg gtcatccact tttgcattta tgatattatt
    58621 taaaaaaatt tatccaggta agaaattttt agtacatgta aaagatagat ttagaaataa
    58681 acttaaattt tcaacagtat ctataataat tagtatacaa gtcctaatag ctgtagtagt
    58741 tatatttata ttagcatcta aaaatcatgg aataatgcct aactttacag tttcatcatg
    58801 gggagcattt atatatttat ttttaaaaaa tttatttgca ggatcattag gtgaggaatt
    58861 aggttggaga ggatttgttc aaaatcatct tcagaaaaga cattctcctt taaaagcatc
    58921 cataacagta ggtttttggt gggggatgtg gcatttacca atatggttta caacaggatt
    58981 caaaggactt gatttaataa aatatattat attttttatg attgcaatta tatcaatcag
    59041 tattataatg acaacttttt ataatctaaa taaaactttg ataataccta ttgcaataca
    59101 tcaactattt aattttttaa tagggataat taatgaagat ttaatagagc ttataaatta
    59161 ctatgcaatg ttatatttaa tatttgcaat tgcattaata gttataaatc caggaaatgt
    59221 attatataaa aatattagag agtaatatat atctttatgg taagatataa agatattatt
    59281 agaagaacat ccaaggagga ataaacatgg ttttactgat tgttgatgca caaaagttaa
    59341 taacaaacga gaggttatat aaatttaatg aatttgtagt aaatgtagaa aatttaattg
    59401 atacagctag aaaaaataat atagaagtaa tatatgtacg tcatgatgat ggagttgaaa
    59461 atgaattgac taaaggtaaa aatggctttg aaatatacga aaaatttaaa ccatgtaatg
    59521 gagaaaaaat atttgataaa aaagtaaata gtgcttttaa agaaactggt ctattagaat
    59581 acctaacaaa taatggtgaa aaagatatta ttattgctgg tctccaaaca gattattgta
    59641 ttgatgccac tataaaatgt ggatttgaac atggatttaa tataatagtt ccagcttatt
    59701 caaatacaac tgttgacaat ttttttatgt cagcagaaca atcatataaa tactacaatg
    59761 aatttatatg gaatgaaaga tatgcgaagt gtatttcatt agaggaaaca cttagaaaaa
    59821 tgaaataaaa atagagtatg aattgtatat gtacataagt tgatttcata aaaaaggatg
    59881 ttaaattcca agttaaaaat tagattaaat atattatatt atagataagg cacatcaatt
    59941 ttattttaaa ttaatgtgct ttttaattgt agtaatttat ttataatcaa tatgattttt
    60001 attatttaaa tcaatttttc ttgagtttct ttgtctaaag aaactttttt tatttataaa
    60061 atctacagtt atattatagt atctatttta gatgagttta atttttgtat caatctaaaa
    60121 caaaagttat acttaaatga aattgaaaac gataaaattc tcaaataaaa taagtattgt
    60181 ggaggtgatg aaagaatcca atgataatat gaagactaat cttaataaga aagtaggggt
    60241 taatggtagt ggacaaagaa attgtatcaa ttctccagat tttattaaat agcacattga
    60301 ttacaactaa tggattacaa gaggagtcta attcatcaaa gagacaaatt acttatagaa
    60361 taaataaaat caatgacatg cttaaagtaa aaaatgtacc acttatatgt ttaagagccg
    60421 acaaagatat tatcgttaga aaagaaacaa aaaaagcaat taaagaaatt ttagaaaaaa
    60481 actattctaa gaatacttat tattttagta agacagaaag acttttatat atgtatttaa
    60541 tgctttttat taacatggag gatatttcaa ttaatcattt tataaattct ataaaagtaa
    60601 gtaggtctac tgtaaatctt gatttcaagg atttgatacc agagcttgaa aagaagaaca
    60661 ttaaagttaa gaacaatcgt ataaatggat attacatagt tggcaatgag atggaaatta
    60721 ggagagtact tattaaaaac attatagaaa ctttgtctaa tgagaaaagt tcaagagtat
    60781 ttgatatttt tattaaagaa tataatttag atagttttga agaggctaaa aaaattatat
    60841 taaagctaat aaaaaaatat gaaattactt ttgttgaaga tagattaata gaatttatat
    60901 atatatttat ctttctaaaa gcaaggatgt attcaactag aatagttact caggaaaatg
    60961 tagatattcc taatatttca gttatgagtt caatgaagga gtataaattt gctaaggaat
    61021 tattagaagt atatgggagt gaagataaga taaagcctca caatataatg tatattagtg
    61081 cttggatttt aggtatatca gtaggaaatt atgaagaaga tacagaagat aaggatgtaa
    61141 tttcaaaaat tgtaaataaa atgatgacaa agtttggata tttaagcgga gtttactata
    61201 taagccaaga aaaaatattt aaacaattat attctcattt tagacctgcc tactatagac
    61261 ttttatttaa attacctatc tataatccga tttgtgaaaa agtaaaagaa gaatataaat
    61321 tagtttatag aattgtaagt aatgcaatga aagagttttg cggattattt ggagaagaaa
    61381 ttcaggaaga agagttagca tatcttacaa tgcactttgc aacacttttt tcaaataaaa
    61441 aagaatttga tggttttaga aaaagaatag cattaatagt ttgttcaaat ggcgttggta
    61501 gttcagctat tttacatgca gaacttacaa acttatttcc tgacttacac tttataccaa
    61561 tgtcggaatc agttggatta gaaaatataa gtgaacctgt agatattgta tttactacta
    61621 attataacgc agagggttta aaaacagatg taccagtaat taaagtaagc cctgttatga
    61681 ccacaaaaga aaaatataag attacacgtg aagtgtatat tcaattaggt gatatttttt
    61741 taagacaacc taaaatagat gaggttatgg atataataaa aaaatatgca aatgtaacct
    61801 ctgaaagtat tctttcaagt gagctattag cttattttac acagatagag aattttacat
    61861 ctaaggaagg agaggggcct atgctaagtg agattactaa tgaaacacta gtaaaaataa
    61921 aggtaaaagc taagaattgg gaggaagcta ttagacagtc agcttctgta ttagttgaaa
    61981 ataacaaagt aactgaaggg tatgtagatg ctatgattaa ctcagcaaaa gcatctggac
    62041 catacatagt aattacaaaa catgttgcac ttccacatgc tagaccagaa gctgggtcaa
    62101 aagagattgc aataggcatt gctactttag atagtcctat tgagtttggg aataacgaaa
    62161 acgaccctgt aaaatatgta ttttgtctaa gtgcaataga caataatagc catttacgtg
    62221 ctatgtctga gctagttgaa ctattggaag aagatgagtt ttttaaggtt ttagatagtg
    62281 ctaaagaagc taaagaaatt attgatttta taaaaacaca cgaattataa aggaggattt
    62341 aattatgtat aaaattttaa tcgcatgtag agcaggagtt ggctcaagtt taatgttaaa
    62401 aataaagact caacaaatta ttaaggaaaa taactttcca attgaagtag agcatggttc
    62461 attggattca ctaaatggat tcaatggaga tgctgtagaa acattaattg atgttgctga
    62521 agaattaaaa aataaaaatt tgaagtttga tataattggg attcacaata ttgttgaccg
    62581 taatgaaata aagacagcac tagaaaaatt ccttgcttca aaagagggat aaatttaaga
    62641 tgataaggag gaatatttat ggagtttatt attagtttgc tgagtacacc tgctgttttg
    62701 cttggcgtag ttgcatgtat aggattgatt cttcaaaaga aatcagctgt tgaagtattt
    62761 acaggctctt caaaaacact tatcggtttt ttgatatttg gtattggtgc ctctgctatg
    62821 acaggagcac ttcaaaattt caataaactg ttccaacatg gctttggaat tactggtgtt
    62881 atagcttcac cagaagcagc tacagcactt gcacaaggta catatggttt tgcagtttca
    62941 tgtacattaa ttcttggatt catattaaat ttagtatttg cacgtattac aaagtttaag
    63001 aatattttct ttacaacagg tcatagtttg ttcttttctt gtgtattagt tttaattatg
    63061 aaagcacatg gatttgataa tacaatcact attttaatag gtggaactat cttagggttt
    63121 atgtctgctg cactacctca attctgtcaa ccatttatgc gtgaattaac aggtggcgac
    63181 gaacaagcta ttggtcactt taacatgatt ggttatggtt tatcaggtta tattgggcgt
    63241 ttattttcaa aacataaaga tgatacaaca gagactatag aatttcctaa gtggttatca
    63301 atattcagag acttcttaat gggtctatcc atagttatgt taatcttatt ttatattgca
    63361 acattaaaag ctggtcaagc atttactcaa gaaattgctg gttcaacaca ttggttggtt
    63421 tttccgctta tagaggcatt tacatttgtg gcaggtatgt caatattgat gtcaggtgtt
    63481 cgtatgttct tagctgaaat aactgcagca tttgtaatca tttcagaaaa gtatattcca
    63541 ggttcacgtc ctgcgctaga tgttccaaca gtatttccat atgcaccaaa tgcagttatt
    63601 attgggttta tatcagcata tgctgctggt ctattagcaa ttgctattat ggcatcattt
    63661 cctagtatat ttcctgtagt aattattcca gctgctcaca tatgtttctt ctcaggaggt
    63721 acagctgcaa tatttggcaa tacttcagga ggatggagag gggctattgc tgggtcattt
    63781 gttgtggggt tattacttgc atttttacca gttatactat atccagttta tggcactctt
    63841 ggtatagaag gagcaacttt ccctaatatt gattacaatg tagttggttc gatattacat
    63901 aatattttac aatttataaa acctatttaa actaaattat ataaaagtat agtcatagtt
    63961 actatgattt caaggaggat acatcttatg gaaaatacat tatctgaatt tttagataat
    64021 atatctaatg aattgtcaga atttattgcc tcaatagatg agacatctat aaataaagca
    64081 tgcgaattaa ttcttgaagc tgaaaaaaat cacggacgtg tacatgtgac tggtattggc
    64141 aaaccaggac atgtatcggg atatatttca tcattgcttt catctactgg aacgtcagca
    64201 tatatattgc atggtacaga agcagtacat gggtcaagtg gtcaagtagt tgaaggagat
    64261 gttgttattg caatatcaaa tagtggtgaa actcaagagt taaaagcaac tcttaagact
    64321 ctaaaagtaa atggagcaaa gataattggt gtaagtggta atgagagttc atttttaaaa
    64381 aatatttctg atatattcct gtttgcaggt gttaaacagg aaggagattg tcttaataaa
    64441 gctcctcgtg cttcaatttt agctgaaaca ataatattac aatcattaag tgttgtatta
    64501 caatatgcta aaggtcttaa tacacagcag tatttgaagt ggcatccagc aggaagtctt
    64561 ggaaagtcta ttagagaggg aatataattt tatgaaatat aaagggatta tatgtgcaat
    64621 gataacacca tttgatgaaa atcaaaatat taattcacaa gcaacatgtc aattaattga
    64681 ttatttgatt gaaaagggaa tttatggatt atttattttg ggcactaatg gtgaatgtca
    64741 tgtattaaca gatgatgaaa aagttgaatt tgcaaagatt gttattaatc atacaaataa
    64801 tcgtgtacct gtttttgttg gaacaggggg taattcaact cgtgaagttg tagatttatc
    64861 taagagaatg gaagcgattg gagcaagtgc attatctatt attacaccat actttgttac
    64921 accaacacaa caggaattaa tcttacatta caaaactatt gctaattcag ttaatttacc
    64981 tattataatg tataatatgc caagtaagac tggaattaat attgaaccag agtcagtacg
    65041 tgaattatca aagataaaga atattgttgg aattaaggat agtagtggta aacttgacaa
    65101 catgaaagct tatattgaag caacgaagaa tgagaatttt agtgtgtttt caggctcaga
    65161 ttcacttatt ctggatagtc taaaagctgg tagtcaagga gctgttgcag caacaacaaa
    65221 cttcctcaca gagattggta tctctatcta tgaaaacttt atgaaagggg atttggaaga
    65281 agctcaaaaa gctcaaagta gtatagaaga acttcgacgt atactgaaac ttggaacaat
    65341 tccatctgtt atgaagaaaa ctattgtctt gaatggaatt aatgttggaa ctgcacgact
    65401 tcctgtaact gaaccaactg gggaagtact tgaagaaatt aaacgagtag ttgaaaatta
    65461 taggacaata cttaataaaa gtagtgagaa tagataatat aaatagggaa attacactgg
    65521 tatataatta atatatatat tataaaacat gactaaaatt aatgaataag taaagtggtt
    65581 tgatgagtat agaggtgata atatgaaaaa gatgaatata accaaaagaa tgtcagaatg
    65641 tggggctctt gcaattgtaa gagaagaaaa tcttaaccgt gcatgtgaaa ttgctgaagg
    65701 atgtataaaa ggtggtataa cagttataga aatgagttat accctaaata atgctggaga
    65761 aataattcaa gggcttaata aaaagtatgg tgaaacactt tgtgtgggag caggaacagt
    65821 tttggatagt gaaacagctc gtcatgctat attacatgga gctcaattta ttattgcacc
    65881 aaattacaat gaaggtgtag cgaagatttg caatagatat cagattcctt atgctccagg
    65941 atgtacatca ttgactgagg cagtagacgc actaagttta ggagcaactt ttataaaagc
    66001 tttcccaata tcagatttct atggacctaa actagtaaag gtatttaaga caccaatacc
    66061 tgatatgcca gttttagcaa gtggagggat taatattgaa aacctacata tatggttaga
    66121 aaatggagtt gatgtatgtg gatttggtgg tttattaact aaaggttctg ttgaagatat
    66181 tgctaaaaat gctaaaaaga ttcgtgaaat cattaaaaat ataagaaaaa tttaacatag
    66241 ggctgtatca tagtatctta taattactat gatacagcct ttttaatatt attcaaatta
    66301 aaaacagttt acatttctat tatattacat ataatttcag taattttatc ttaatttttc
    66361 tatctggaaa aaaatgattt aaaacttaag ttatgatata atttcattaa aagaaggcga
    66421 tttttagtaa atatgagaaa ataatgtgtt tttaggggaa aagttaaata cagatttaag
    66481 tgaacaagaa tcgataatta agatattaaa tggtgaatag ggcatcaaaa aaattactaa
    66541 attaaaagtt ttagagggag aatcttagca agtgtgtgtg aaaattcaat ttcaaacaaa
    66601 aaataattgt aaatgaaatc aatttataca cgttgaagat tcacttttat cattatatta
    66661 aaaagcagag tgaattaaaa gtgagtctaa agataggagg ataattaaaa caatgaaaga
    66721 agacattagg ttacatcgaa tgtgtaaaaa agaacaagca acaaagaatg aagttatatc
    66781 agaggatatt ctaaaatcta tgagtattgg ggtcagtaaa cattttttag atgattcatt
    66841 tacaataata tggggaaata catcattcta tcaattatta ggatatacag aagaagaatt
    66901 tttagttaaa ttttctagtt taaaagatta ttatgaacag aatctttatc attttgaatc
    66961 tatgaaaaat cattttttag aggcttatca tcatggcgaa aagagtatag aatatcaaat
    67021 ttgcatttca gcaaataatg gagaccctgt ttgggtaata atgactggta tattaattga
    67081 atcacaagat aatgagaaat caatggtcta tatattgtat tcaaaaatta atgagttaaa
    67141 aataaagcaa gaagaactat ctgatatgga aaaagagagt acagagaatt ttaaatggat
    67201 gatgtcagag tatgctggga atgtttatat tagcgatatg gatacatatg aattactata
    67261 cttaaataag cactcatgca atactttaca ggcatcagca aatgaactta ttggaagaaa
    67321 atgttatgag gtaattcaag gtagaacttc gccatgtccg ttttgtacaa attcgtattt
    67381 aaaaaaagat gacatatatg aatgggaatt ttataataaa aaactgaaac gaacatttat
    67441 aattaaagac cgtatgttga attggcaagg gcgaagagtt cgtattgaat tatcttatga
    67501 tatgtatagt gctgaatata aattagcaaa aaaagatcag gaaagagaat caattttgaa
    67561 aactattcca gcaggaatgg ttagattaga tgcaagagat tatcttacta tactttggtg
    67621 taatgatata tttttgaata tgattgaata tacaaaggaa cagtttgcag aggaacttaa
    67681 taatcaatgt ggatatttat tttctgaaga ttataaacgt agtaagaaac tggcacaaga
    67741 tttgaaggag tctggggata atgttgtatt tgaagcaaaa atatatacac gttcaaggga
    67801 agaacgtata tggactgtta cattgtgtta tatcagtggg gaagacagtt gggatggaat
    67861 accatctttt tatagtatag gtattgacat aacaaaggaa agaaaacaga ttgagaaatt
    67921 acagcatata tcagagaaag atgcattaac aggaatttat aatcgtgctg agactgaaag
    67981 gcagattaag aaatattttg aaaaaaattt aaatgttatg ggtgcactgt ttatgattga
    68041 tacagataat tttaaacaga ttaatgatac agaagggcat atgattggag atatagtact
    68101 tactgagatg gcatcaggta tgaaaaaaat aatgcgtgac agtgatgttg ttggaagaat
    68161 aggtggagat gagtttacaa tttttatgaa gaatatttcc tcagttaaag atgcagaaaa
    68221 gaaagcagaa gaactattgt atatgttccg tcatctattt cagaaagaaa aaagttttct
    68281 aaaagtaact tgtagcatag gaatagctat atatccaaag gatggtacta cattcaagga
    68341 aatatatgca agagctgata aagccctgta tcaagcaaaa aatatgggaa aaaataatta
    68401 tgtaatctac aaccaagatt attttaaaga attagaagaa tttgattgtt cttctcttgg
    68461 tacagttatt gattcagaaa aacaatacgc tgaatatcct gataatctta cacgttatat
    68521 attccgtatg ctttatcaga ctgatgatat agaccaggcg attaatatga tacttgaggt
    68581 tgttgggaaa cagtttgatg taagtcgtgt ttatattttt gaaaatacag aagatggtag
    68641 atatacttct aatacttatg aatggtgtaa tgaaggaatc tcttctcaaa tggcttattt
    68701 gcaaaacagc aattatcaag actatgagga ttatgaaaag ctttttgagg atgaattagt
    68761 tttttattgt cgagatatcc atacattaag tcctaaacta gaagaattgt tttctagtca
    68821 aggtatccac tctacacttc aatgtgcata taaagaagat agagttttca gtggatttgt
    68881 tggatttgat gaatgcacag gactacgtct atggtcacaa gaggaaataa gtacattatc
    68941 attgatttct caaattatat caatgttttt acaacgtaaa aaaaataata aacttaatca
    69001 acagattcaa caataccaga atattttaga taatattgac cagtgtattt gtgtgattaa
    69061 taaagaaaat aattttttat tatatgtaaa taaaaaattt aaaaatacat attctaaatt
    69121 ccaaattgga caaccttatt atcttgattc tatagatatt cataagatat ccattatatg
    69181 gaataaaaaa gaagcatacc tatgtactag cacgatttaa tggtaaagta aagtttatat
    69241 tggacttaaa ttaaatttcg ttttaaataa gatattattt tagttgctta ctgaaaagac
    69301 tagaatctat attaatgaat tatactaatt ttataccact attaaaatat tgtttgctaa
    69361 aaataaaaaa tagccttaaa acagttgatt ataaaaaatt aactgcttta aggctatttt
    69421 tatctttgtg acgaaataga cacttgccat ttagaatgtg acaatatagt agttgtttag
    69481 aaaaggcaca aagcattata ctttaactaa agtaaaatgt attttgcttt tagaataaaa
    69541 acaattagga gggagctata attgaaaaag ataatatatg tattatttac aattgaacta
    69601 ttaatagtat ctttattagg tctaaatata gttaaagata atgaaattaa taatatttta
    69661 tataacgaga caacaagtat atctgtaatg tttaaagatt ataaaaagtt aaataaaaat
    69721 tatagtaagt ggattaaaga tattgcagat gaaaataatg tgactatatc aaagtatgtt
    69781 tttaataata atgaaaaatt atctatatat acgactgata caagtttgaa taacaatata
    69841 aagttaaaat caggaaaatt tcctaatact aattcaaatg aatttattag taatataaac
    69901 actaataata gtaatcaagt aggtaaattc tcaactatga gtaaagacat atcaatttta
    69961 attagggatt ttggtaaaat aagtgaagtt ggagaatcag gaatcttata tatttcaact
    70021 caaaatgaag atacaataaa taaaatatta agagaactaa atgtagacag aagtattttt
    70081 gtagcaagat tacatgatag atatgttaac tcaaatttat acttaaatcc ttcaataatt
    70141 agagatttaa tactaattat cctttgtttc ttggctacaa taatacatta ttcaattagt
    70201 gtgagtagag aggcttctat tttaagatta aatggatact ctaagctaga tataattgct
    70261 agagttataa aaaatatact tagaattatg attttatcat ctgtcacagc attattaata
    70321 tatataatct atattttaaa attaaatata ggtgttagag catgcttata ctttgctatg
    70381 ttttcgatta tatgtatttt gataaatatt ttgatatcta tattaatagt tggttttaat
    70441 agtagaagtt ctaaatatgt gctatctcta aatggaaaaa aatcttatgg ttttgtaaat
    70501 ataatgcatt tcacattgaa aattgtattt gtatcatttc ttatattatc cataaataac
    70561 tgtattttaa attataatat gctacaaact cagttaggaa atctatctga gtgggataaa
    70621 gcaaaaaatg tttataatct tactcttaaa gatacaggcg aacaatcttt aggaaaggaa
    70681 gaagtaatta aaaatgccaa gattaaaggt ttctataaaa atttggtaga agaaaaagat
    70741 gctttcttaa tagattcaac taattttgaa aaacttgaag atggaagtta catgtatgaa
    70801 ataaattcaa agggtaaaaa cccagaagta agtcaatatg gtaaaaatat aaaaataaat
    70861 aaaaactatc ttaaagttaa ccctatttac tcaaatggca aagaaatatt taatctaatc
    70921 gattatgacg ataagactat aaatttatta gttcctaaaa agttacaagt acatgaaaat
    70981 gagattaaaa aagagtttag agaattattt tattttgaaa aaatagaagt agaaaatatg
    71041 tacaataaag agttaaatag agcgttaaac aaaacaaaga agtcagattt aaatgttaat
    71101 ataatatatg tagataataa tcaaagctat tttacttata actcccttgt tatggatgac
    71161 aataggaatc tcattgatga cccaatagca atagttgaca tagataatat tgatgattct
    71221 ttttatcttt cttatatatc tagatgtgta tattttaatt ctaagaaatt agatgccctt
    71281 gcagatataa gtagcattat tgaagctcaa ggtgtagaag cgcatatcca aagtttacat
    71341 gctgtttata atgagtatgg tttagaaata aataaactag aaaaatattt gaatagtgaa
    71401 atttttacta taataataat agcaatatca aacttaatga ttacctacaa tatagtagct
    71461 agctactatg aaagaaataa atataagtta tatattaaaa aaatatttgg ttattcaact
    71521 acagctagaa gtatgttgtt aatagtctca ttaatattaa caaacattat tccaataggc
    71581 attat
//
LOCUS       DAEPHU010000010        70338 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 01A10CD0081
            SAMN05941466-rid12468953.denovo.010, whole genome shotgun sequence.
ACCESSION   DAEPHU010000010 DAEPHU010000000
VERSION     DAEPHU010000010.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941466
            Sequence Read Archive: SRR6291087
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 70338)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 70338)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068158.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 22:43:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,892
            CDSs (total)                      :: 3,805
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 87
            rRNAs                             :: 8, 1, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 55
            CDSs (without protein)            :: 55
            Pseudo Genes (ambiguous residues) :: 0 of 55
            Pseudo Genes (frameshifted)       :: 21 of 55
            Pseudo Genes (incomplete)         :: 28 of 55
            Pseudo Genes (internal stop)      :: 16 of 55
            Pseudo Genes (multiple problems)  :: 8 of 55
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..70338
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941466-rid12468953.denovo.010"
                     /strain="01A10CD0081"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            287..1504
                     /locus_tag="KR231_000719"
     CDS             287..1504
                     /locus_tag="KR231_000719"
                     /EC_number="4.3.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine ammonia-lyase"
                     /protein_id="HBH0003126.1"
                     /translation="MMNVTLTDVKEARETIKNIVKRTDLLESVKLSEKTGANVFYKCE
                     NLQKTGSFKLRGACNKIASLTDEEKANGVIASSAGNHAQGVALGAKMTGIKSTIVMPA
                     TAPLAKVSATKGYGAEVVLNGAVYDDAYAKAVEIQKETGATFLHPFNDKYVIAGQGTI
                     SLEIFEQLDNKVDTILCPVGGGGIISGVAVAAKALNPNVKIVGVQTANIPSMKESIKN
                     GKVTTAFNDTTIADGIAVKTPGDLTFEIINELVDEIVVVEETEIAESILFMMESQKIV
                     SEGAGAVCTAAILSGKYVPAKDENVVCIISGGNIDINTLYRIIGVALAKEGRRYSFST
                     IMEDKPGNFAELTRIISENGGNILSANQGKLSAGEALGKQSAEFILETIDYDHIARIK
                     KAIEEKGFKIIEL"
     gene            1599..1979
                     /locus_tag="KR231_000720"
     CDS             1599..1979
                     /locus_tag="KR231_000720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RidA family protein"
                     /protein_id="HBH0003127.1"
                     /translation="MKHEVIHTNDAPAALGPYSQAIKAGNLLFVSGQVPLVPETMEVV
                     EGDVQAQTAQSLKNLKAILAESGADFSNVVKTTVFIKDMNEFGAINEVYAEYFGENKP
                     ARACVEVARLPKDVKVEIEVIAVL"
     gene            2263..2745
                     /locus_tag="KR231_000721"
     CDS             2263..2745
                     /locus_tag="KR231_000721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HBH0003128.1"
                     /translation="MLNFFKKNKSYKLHAVVSGNSINIEKVNDSVFSKKLMGDGVAII
                     PNSNVVVAPCNGKVTVLTESKHAFGMVSDEGVEILVHIGIDTVSLQGEGFKNEVSQGD
                     TVKKGSPIISFEREKINSQGIDCTTIIIVLNHSEFSEINCMVENEVVAGQDTVIEIMK
                     "
     gene            2766..3581
                     /locus_tag="KR231_000722"
     CDS             2766..3581
                     /locus_tag="KR231_000722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HBH0003129.1"
                     /translation="MRVVKIFNNNALSTVTNDRKEAILLGLGIGFNKRPGDKVNEDKI
                     EKIYYVQDHMQTKFLELLKNVSPEVMDASQQIISLIPGNEGKFNNKGILSLVEHISFA
                     IDRMKNNVFLPNLMLLDIKMMYSKEFELGVKALEIIYRVCHIHLPEDEAGYIALHFVN
                     LQSNDNLAYDTLKFVKGSIDLIKECYGLELDESSLSTLRFRTHLKFLAQRIFKNEICQ
                     DDKMIEMYDYLINNHPKNKEYLEKLNVYIEKEFRYKLDKPEKIYLLLHLTKIL"
     gene            3634..5184
                     /locus_tag="KR231_000723"
     CDS             3634..5184
                     /locus_tag="KR231_000723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HBH0003130.1"
                     /translation="MKEKLLGGLETFAKAMVQPLMYLSSAGILMVVGVLLTNDMLLGV
                     LPFFKWEPIQIFGSLIYNCIMAIINNLAVIFAIGIPAALAKKEKHKAALIGFMSYIIY
                     LTASNTMLTSLGQLAKESKMLGLIGTGQATILGIQVVDTSVFGGIILGYIAGYVFNRT
                     SNKTFKGALQIYSGANFSFICMFFVSILIGVVSNFIWPLAQQGIASLANVIKDTGTFG
                     LFLYGFLERILVPTGLHHLIYTPFQFSDLGGVLKVGADTVSGAYAIVMTEMNLPVERF
                     SDSIYYMATGFTKMFGYIGIGAAFIYTAYKQNKKKVKATIIPLIITAVLASVTEPLDF
                     MFVFCAPLLFFVHAVIAGLFIALLKIFDVTALCGGNLLVSVIMNTTVGVEKTHWPVMM
                     ILGLAQIIVYFVVFSFLIKKFNYKTPGREDESTATGEEQSKQLNLDAGIENIIDGLGG
                     KENINTVENCITRLRVNVKDESKINEDIINLTPNSGIVRKGKDIQIIFGLHVHEVRRA
                     VEDFLEAY"
     gene            5281..6633
                     /locus_tag="KR231_000724"
     CDS             5281..6633
                     /locus_tag="KR231_000724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-alpha-glucosidase"
                     /protein_id="HBH0003131.1"
                     /translation="MIITIVGGGSTFTPGIVKSIALREKELELEEIRLFDIDKKRQDK
                     VAVVVNWILKEDVKTDVKLTVTNCEKEAYTDATFIFAQMRVGKYEMREQDEKIPLKYG
                     CVGQETCGCGGMAYGLRTIQPMIKVIDDVEKYAKKDYWILNYSNPAAIVSEACRKLRP
                     NARIINICDMPIAIIDMIAGSLNINDVHNIRYDYFGLNHFGWFTSIDYKHRDLMEEIK
                     EYIKENKILLPKSYIENLNKSRSTGNRHAVSSWIHVWESVYTMLESFPKYLPNTYLTY
                     YLLSKETVEHSNINRTRANEVMESREKDLFEGVRHYLETGEISEKAFYAGSHGDWISD
                     LAVSIKNDTRSRFLVITENRGAIPNMPYDAMVEIPAYIGKDGPEVIARGPIPLFQQGL
                     MMQQLNSEKLIVEAYIENSYEKALQAFTLNKTIPSMNVAKEILDEMIEVNKEYWPELR
                     "
     gene            6764..7522
                     /locus_tag="KR231_000725"
     CDS             6764..7522
                     /locus_tag="KR231_000725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBH0003132.1"
                     /translation="MNIINKIFWQEDRIGMITNNLEADTHSHCMLQLFLGIEDSIEIT
                     VNEKLVKCNCIIVDKNISHSFSARKKVYYSAIIEPTSIYAEQLTSKMNDFGYWICDND
                     GLEKLRQQGTFLISNSSKEQYLRFMEMLNNYLNIPITLKHYDDRITELFNLLHTCNCD
                     NHTISSFADKVSLSASRLSHLFKEQIGIPLKSYILFHQMECAFRELLSGKNVTEASMT
                     AGFDTPSHFAGTVKRMMGMPVSLSLKDSEFLKVY"
     gene            7569..8288
                     /locus_tag="KR231_000726"
     CDS             7569..8288
                     /locus_tag="KR231_000726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transglutaminase domain-containing protein"
                     /protein_id="HBH0003133.1"
                     /translation="MNKEYLEETKMLNYNEPQLKLLVSSKNWLELDDFHKIKSIYEFV
                     QNDILFGYNASDMLSATQVLNDGMGQCNTKATLLMALLRAVNIPCRLHAFDVTKDFQR
                     GATSKLISLLAPKYILHTWVEVFYQDRWIALEGVITDKKYLEAIQKKFFNHGGTFKKY
                     AIATNDLKNTSIDWDGKDTFIQKEAIVYDYGIFPSPDVFFSTHSQHMSKLKNFIYVHL
                     IRKIMTKNVCKARNNYIDKNE"
     gene            complement(8412..9812)
                     /locus_tag="KR231_000727"
     CDS             complement(8412..9812)
                     /locus_tag="KR231_000727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter"
                     /protein_id="HBH0003134.1"
                     /translation="METQSNNKKGNLIIAIVMTGAFISSLSQTLLSTALPNIMSDFKI
                     TADVGQWLTTIYLLIAGIIVPTTAYLINRFSTRKLFITSMSIFSIGCIIALFSNNFST
                     MLIARVLQAMGSGSLMPLLQVIILYLCPEEKRGAAMSLVGITVGFAPAIGPTLSGWLV
                     DSFGWHSLFLFLSPIAILDVILSFILLRNVGETQKLKLDIPSIVLSSLGFGGLLIGFT
                     NQGNYGWTNIATYLPILIGIMSLILFTLRQLKSKEPFLELRVFKNKPFLISTILIMIV
                     YASMMSATLMIPLYVQSVRGFSALSSGSLMLPGAILMVVLNPIAGRHLDKYGPHALSI
                     LGTGCLFLGTLSFAFLGRDTSLIHVSLMYCIRMIGISMVLMPLTTWGIKTLDRELISH
                     ATAINNTLRQISGAIGSAILITIMTSATKKAHMSSNMLSNIHGIDVAFSIAATLAFTG
                     LIVSICFIKRHQIIRS"
     gene            complement(9816..10724)
                     /locus_tag="KR231_000728"
     CDS             complement(9816..10724)
                     /locus_tag="KR231_000728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBH0003135.1"
                     /translation="MKGDNKVTEKQRLIITIAQKIFDQKGFQNTSISDVVKECKMSKA
                     TFYKHFETKESFICEIINYYDEKFLEIIHSINENNDIPASEKLNRKIIAVWKNIFSRT
                     TINTYIRENFSEEQRKATSKLQTKSRANLLNEYKLSLFDNYGDKIEKIIFDLVFLLDA
                     LIHQFIYIIHVQKREINVYFIAKFTIQILDLVVENMDNLNPLIEKSMFLHKQEDEVYF
                     SLHNKSLFFKMIQDIEELIKTDTSLLENPKLLEAIKKLYVEGKNQQYDSLIMDAMIAY
                     LEKEDTLRPKVLLLNSIKNQLKKETL"
     gene            10985..11632
                     /locus_tag="KR231_000729"
     CDS             10985..11632
                     /locus_tag="KR231_000729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M15 family metallopeptidase"
                     /protein_id="HBH0003136.1"
                     /translation="MKKKICVAIIFALFIVFVEMFIDSSSEGSKIMTAELSKYRKGVN
                     VLSINNIIVANKKYSLPKDYSPQESSEARDAFYKMNKDAQKSGLNLKAFSTYRSYEYQ
                     DRLFKSYVKEHGEKEANRFSAKPGESEHQTGLAFDIGGDDQSCWANKKFNNTKEAKWL
                     YENAYKYGFILRYPEGKENITGYMYESWHYRYVGTEHSKNFAMNNLTLEEYLHIN"
     gene            11956..14595
                     /locus_tag="KR231_000730"
     CDS             11956..14595
                     /locus_tag="KR231_000730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HBH0003137.1"
                     /translation="MSYKSTYQEVIKNLDSSLSGLSKERAEELLEKNGANELKEADKV
                     PTYKLFLESFKDPLVIILLIAALVQIFLGETVESIIIFAVIIINSVLGVVQTKKAESS
                     LESLKNLSAPNAKVIRDNKKMTIPAKNLVVGDIVFLEAGDYIPADGRLIEAQSLKVVE
                     GMLTGESEPVLKHTEKISEDVSLGDQKNMVFSGAVVVYGRGSFVVTGTGMDTEMGKIA
                     GLLESAENKLTPLQQKIEDFSKKLGVGIVILALLIFIIQVARNYFMAGNGEMTQIILD
                     SFMFSVAVAVAAIPEALSSIVTIVLAVGTNSMAKKQAIIRKLPAVETLGSTSVICTDK
                     TGTLTQNKMTVVDYYMYGTNNDELDKEKVNYSYHAKLLTMVSTLCNDSHITSDGKEVG
                     DPTEVALINYSSKNDLDYDKLRSKYIRINEIPFDSDRKLMSTVNSIYGDYIMFTKGAP
                     DIVFSRCKYALKNGSKVDITDEIIEEYKHKNEEFSNRALRVLAFAIKDVPEEDFIPSI
                     DDEHDMTLVGIMAMIDPPREEVMDAVKEAKSAGIKTVMITGDHKTTAAAIAKEIGIME
                     EGDLALTGKELDALSEEQLYEKLENISVYARVSPENKIRIVKAWQHKNNITAMTGDGV
                     NDAPALKQADIGIGMGSGTDVAKDASAMVLVDDNFASIVNAVEVGRTVYSNIIKSITY
                     LFAGNLGAIVSIVFAVFAGWSNPFTALQLLFINLVNDSLPAIALGFEKSEKNIMNKPP
                     RHPDESILAGGTLKAVAIRGCIIGVVTIIAQYIGLQVSPELGVAMAFSTLILARIMQT
                     LPARSNNQTVIKLGFFSNKYVIGAVLVCLGLYSLTLIPVLRGIFSIPTTFGLYQLGIC
                     LGLALISSILMELNKLINRSEVK"
     gene            complement(14653..15756)
                     /locus_tag="KR231_000731"
     CDS             complement(14653..15756)
                     /locus_tag="KR231_000731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidinol-phosphate aminotransferase family
                     protein"
                     /protein_id="HBH0003138.1"
                     /translation="MKLKINKAIEMQLKKSYAIESGHSEDVFEIDCGEGINTVSYSNK
                     AVEAFNALKFDMIRGYPHSIALKDNIVDYWKDFIALDTDRICLADGSIHVIYLLNRLF
                     IEKGDKVLGYSPQFSEYETDIKMHGATYDYVLLKKEDNFKFNEKEFIEKINPEYKVIY
                     IDNPNNPTGQIIHLSSIENIVKEAAKYDIAVMVDEAYGEYMPKENSAVKLLNNYDNVI
                     ALKTFSKGFGLAGLRAGYAVLPEQLVSPIKKISTPYEVSEISRSIAANLLDDVQFIEE
                     LKEKTKDIKNQLLIPWKNLNIAETSDTVSIMTVEHKNKDIDLQQEFAKLKIRVISGSD
                     FTGLDKNFIRFRMPEEKELPEVIKAFQIIDNIE"
     gene            16117..16938
                     /locus_tag="KR231_000732"
     CDS             16117..16938
                     /locus_tag="KR231_000732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HBH0003139.1"
                     /translation="MGYKLIVTDMDGTLLGNNHKVTDENKTALQKVIKSGINVTLATG
                     RAFDSAKCNVDFLKEDMPIIACNGSLIREQNGNIIYSNKIDTRTCLNILDVLDKYDIY
                     YQCNSIDSMLSKKIEGREDRLSVFLGSETEVIVKDDLREEIFKKDILKFVIIEEKNPS
                     ILDEIRKELRKVQGIKITSSWPNNIEVMNEGVDKGNAVKILAEKMNIDREDIIAFGDN
                     YNDIEMIKFAGLGVAMGNAEELIKQEADYVTDTNQDSGVAKAIYKFLELKESLSS"
     misc_binding    17017..17228
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            17315..18631
                     /gene="argH"
                     /locus_tag="KR231_000733"
     CDS             17315..18631
                     /gene="argH"
                     /locus_tag="KR231_000733"
                     /EC_number="4.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012101354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="argininosuccinate lyase"
                     /protein_id="HBH0003140.1"
                     /translation="MKLWGGRFRKAENQLMEEFNKSFGYDCVLYKKDIEGSVAHVHMQ
                     VKCGLLTEEEGKSITEGLKGILEDVENGKLVLDGEYEDIHSFTEINLIQRIGDVGKKL
                     HTARSRNDQVAVDMRLYAKEKANDLVGLISEFKATIKDVADKNPVMMPGYTHLQRAQV
                     VTFKHHLMAYYSMFDRDEKRIKNAIEILDESPLGCGALAGTTHDIDRSITCEQLGFKK
                     VVDNFMDGVSDRDYLLELMSDFSIIMMHLSRLSEELILWSSQEFGFVEIDDLYTTGSS
                     IMPQKKNPDGAELIRGKTGRVYGNLFGLFTVMKGIPLAYNKDMQEDKEGFFDSVHTLE
                     MCIQIMDRMIATLKVNEDKMKQAVKNGFLNATEVADYLVKNNVAFRDAHGIVGSIVIY
                     CEDNKKAIEDLTLEELHKFSDAFKEDIYDFIDYESILNKGIKKNLK"
     gene            18880..19218
                     /locus_tag="KR231_000734"
     CDS             18880..19218
                     /locus_tag="KR231_000734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2325 domain-containing protein"
                     /protein_id="HBH0003141.1"
                     /translation="MNLLVIGGHERMEKDYMVMAKKKGYKTKVYTTMSSKLNNSIGRP
                     DAVVILTSTVSHKMSRTVESQAKKQDILIVRHKNSSKVAFNECLDMVDECLGNCSKCK
                     LKDKQKQKNI"
     gene            complement(19345..20634)
                     /locus_tag="KR231_000735"
     CDS             complement(19345..20634)
                     /locus_tag="KR231_000735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase"
                     /protein_id="HBH0003142.1"
                     /translation="MKRNLSLLLICLLIFTSFLGSSNISFADNEPAIVAKHAVLMDYE
                     SGKILYNKDGNSKLYPASTTKVWTACLVLKEVKDLNQVIEIKDLPQIDGSSMYLKNGE
                     SFTVKQLLDALLVHSANDAAFVLARYVGGGNVQKFIDLMNSEAKKIGATNTHFNNPHG
                     LPDPNHYTTAHDMALIAREAMNNDTFRQIVKTKSLKFEATKAYPYERYFVNTNKFLTS
                     HDKITYKGQPINIKYDIVDGIKTGYTDAAGKCLLSSAVKDGRRVIVAVFNSTNADLYL
                     DSRILIDYGFDNFKCATIVDKEKYTDTKKVLFTKQHELIYEPKNSYRIFLEKDESQGN
                     YDTKTELNKIDLPIKKGAKVGTLNVYNNGKLENSIDLIAKNNLDSSLPFFTGNNILMT
                     FVKIIAGILVLLVLFIIASNIKKKKRKKARSKKNMKK"
     gene            20714..21418
                     /locus_tag="KR231_000736"
     CDS             20714..21418
                     /locus_tag="KR231_000736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-hairpin-helix domain-containing protein"
                     /protein_id="HBH0003143.1"
                     /translation="MKKKVKFISFFVLFILIISSIIVYKSLIFKDDIYVVSKKNLPNE
                     KTHVVENEIKGEDNNHNKVTKDIDKNFQNNKITIYISGAVNRPGIVTIESDKRLYDAV
                     ELLGGTTKEADLNGVNLSVRLEDEQHYIIPKIGEATSVTSNDDSNKPNQRNESRGEPK
                     NKSNKNISNESKVNINVATIEELDSLPGVGEATANKILQHREENGQFSSIEEIKNVNG
                     IGDKKYENIKDLICVD"
     gene            21510..22556
                     /gene="selD"
                     /locus_tag="KR231_000737"
     CDS             21510..22556
                     /gene="selD"
                     /locus_tag="KR231_000737"
                     /EC_number="2.7.9.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015617929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_except=(pos:21558..21560,aa:Sec)
                     /transl_table=11
                     /product="selenide, water dikinase SelD"
                     /protein_id="HBH0003144.1"
                     /translation="MKKEQKKLTEMTTAGGUAAKIGPEVLASVLSQLPKNDNIENLLV
                     GLDTADDAAVYKLNDDMALIQTLDFFTPMVDDPYVFGQIAASNSLSDVYAMGGKPLVA
                     MNIVCFPSCHDMDVLAEILKGGFDKVKESGALLVGGHTVDDKEPKYGLSVSGIVSPNK
                     VLSNATAKPGDKLIITKPIGVGVLNTAMKEGMVEQHIADKVIEIMIHLNKYAAMSFEK
                     FDVNSVTDITGFGLLGHTLEMAKASEVSIEIESKHVPIIEGAIEMAQMGIIPAGMYKN
                     MHYVSKDVEVVGNIEVAVQDILYDPQTSGGLLISVKEELAEELVKDMKLNGAIEAKII
                     GSVVPKGEKYITVL"
     gene            22574..23986
                     /locus_tag="KR231_000738"
     CDS             22574..23986
                     /locus_tag="KR231_000738"
                     /EC_number="2.9.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-seryl-tRNA(Sec) selenium transferase"
                     /protein_id="HBH0003145.1"
                     /translation="MIVLSKRELFAMLPSVDEVLSDNRIVEIINEYPRSLVLESVREV
                     IDLKRQFILRLKEDASNSVTIEFGEIIESAIERVKLNYSLSLKKVINATGTVIHTNLG
                     RSLLSEDIKDELWCAASRYSNLEYDLDNGERGSRYSHLTSTIKRLTGAEDVLVVNNNA
                     AAVLLVLSTMAKGGEAIVSRGELVEVGGSFRIPSIMALSGAELVEVGSTNKTHLKDYK
                     EAITEDTNVLMKVHTSNYRIMGFTESVSIEELVNLGKKYKLPVIEDLGSGVFIDLSKY
                     GLSYEPTVLDSIRQGADVVTFSGDKMLGGPQAGIIVGKKEYIEKMKKNQLTRALRVDK
                     LTICALEATLRMYLDETKAIENIPTLKMLTYKIEELEVKANKLFEKITALNLNANINI
                     EDGFSQVGGGSMPLETISTKVISITPEHMNVSSLEKKLRLSEAHIIARVYDNKYVLDV
                     RTIFDDEFDVIVEELRKAFN"
     gene            24100..25983
                     /gene="selB"
                     /locus_tag="KR231_000739"
     CDS             24100..25983
                     /gene="selB"
                     /locus_tag="KR231_000739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="selenocysteine-specific translation elongation
                     factor"
                     /protein_id="HBH0003146.1"
                     /translation="MKNVVIGTAGHIDHGKTTLIKALTGRETDTLDEEKKRGISINLG
                     FTYFDLPNNRRAGIVDVPGHEKFIKNMLAGASGIDIVLLVVAADEGVMPQTVEHLDIL
                     SFLNIKNGIVVLTKSDTVDDEFRELVKEDICEKIKGTFLEDAEIIEVDSISKRGIDTL
                     IEKIDKMSDDIEDKNENSPARLNIDRVFSIKGFGTVITGTLIEGKISIEDDLVIYPQV
                     LKTKIRSIQVHGENKDTAYAGQRTAINISNVKVDDIKRGDVLAAPNSLEESMMLDVKL
                     SLVNHLDKGLKHWDRLRLYHGTREILCRAVPLDKELIESGESGYVQLRLEESIVSKKG
                     DTFVVRRYSPMETIGGGVIIDPSPKKHKKFDEKVIEALKIKEKGELKDIIEEYLKRNL
                     KNYPNIKEIMSYSGAHEEDVKRALETLISEDKVFIIGNMYMHINQYNKLKENTIKLLS
                     EYHKKYRLRKGILKEEVRSKIESNFKTREMDILLEKLSTENAIKIENNIVSLLDFEVI
                     LNDKQKEIAKKIEKRLKSCGVSSILTIDEVSEGNHNYAEVLESMIGNKVEKLDDLYIM
                     DKDIYENAKNILINYIKENKEITLGEYRDLIDSSRKNCMIILENFDRNKITKRVENKR
                     ILF"
     gene            26088..28826
                     /locus_tag="KR231_000740"
     CDS             26088..28826
                     /locus_tag="KR231_000740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sporulation-associated two-component system
                     sensor histidine kinase"
                     /protein_id="HBH0003147.1"
                     /translation="MKNIIPDVKPDIKEREDMSLLFIIMGSVLLLFIIKDIEKYETLL
                     HAIYTIFLVATGVIIFNTTKFKVDSFSTFLGLIFIATGVLECIYLFNSLGIKTKSIME
                     INITISAITDLFPILGVYLSFKFVKDNKQIYSSVILFIATATLTITSLFIISGICDYL
                     GNGKSQYALGVIISIFIIIISIISGIELNSSSNKGKWEYDEKKIFNRIIVIIILSRVP
                     NLLHIVIDNRNVERILSQIIINVALYYLYNYIVSKNIKKTALELHDTNEELTKKTESL
                     KEKNKKLIYETEKIEELKGILMKRESRLQSTLDVAVNSIVVFSKDGEITYANKSFRNT
                     FGDYKEQDKLTDKIKNFNDLIESIHYVFVHEKNAEKLISTSDNKVYQAIFAPLIIASQ
                     TEGVLCVLEDKTKKKEYERKLIEANKRSKDFLESIGDGIVVLEGNNKIYVNNACREIF
                     KNNLESIDFSLVCKSEESIEKRYVIDGEVKYVEMSFSQYTNAGTNKTIIVIRDTTSRK
                     ISQIKLEESQSSYSRFIDILPDGICLLKEDLSINYANKSFLDMLAFTNIDDIKDSNIK
                     LLMNANTEEKMKFTDNMAKVLNENRSILLLEYELINSYDDIVEVELSALPFAIYNTRY
                     IMLIIKDLVHKKYSEQAEKELLERFKTDKIKTEFFANMSHELKTPLNVISSSNQLVDS
                     FYRNEKIKDYNNNIKSHVDLVRQSSYRLQRLINNIIDLTKMESGFYTLKLAKYNIVSV
                     IEDLFMNIEEYALRKDIKILFDTDLEEINVYIDKVEIERIMLNLLSNCIKFTDNGGWI
                     YVSIHYKIDKVIISVKDTGVGIPQDKLELIFEEFSQVDKTLSRNTEGSGIGLAIVKNL
                     VSLHGGDIEVVSEVNKGTEFLISLPMKGFSSEHYTEDKRIYNIQEKIKIEFSDIYY"
     gene            complement(28945..29889)
                     /gene="manA"
                     /locus_tag="KR231_000741"
     CDS             complement(28945..29889)
                     /gene="manA"
                     /locus_tag="KR231_000741"
                     /EC_number="5.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannose-6-phosphate isomerase, class I"
                     /protein_id="HBH0003148.1"
                     /translation="MEPLFLKPIFMDRIWGGTALKDKFNYEIDSPTTGECWAISSHKN
                     GDCLIENGKYKGKKLSELWNKNRELFGNTPGDKFPLLTKILDANDNLSVQVHPNDEYA
                     KKNENGELGKTECWYVIDCSDDAEIIIGHNAKSHKEFVNMVNNNEWDKLLRKVNIKKG
                     DFFYVPSGTIHAICKGTLILETQQNSDTTYRVYDYDRTDNSGNKRELHVQKSIDVTNV
                     PHINFDTDYKIVSTSDFKCTTFVSNEFFSVYKLDVFGKCNFTHNTPFSLYSVLDGNGK
                     LIHNSVEYNLKKGMHFILPNDFGDFSFEGNLEIICSHI"
     gene            30062..31423
                     /locus_tag="KR231_000742"
     CDS             30062..31423
                     /locus_tag="KR231_000742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallopeptidase"
                     /protein_id="HBH0003149.1"
                     /translation="MELFKAESKKYKKEFLKLLEQWVSIPSFYDRKTVSKDMPFGKGV
                     YDALNWFENLGRENNFKVKNIDNHAVQIEYGNGKEYVDIFGHCDVVNPGEGWDSEPFK
                     LNIIGDKLVARGVSDNKGPMIVNFLALKMIKDLDINLKRKVRLIAGGNEESGFKCIKH
                     YYSKEPYGVCGFTPDAKFPVLNGEKGGAIIKLISNIDDKSLYISGGIEFNTIPDKVYI
                     KNVEKLGKDNICFDINNISINYDNGNYIVYGKGGHSSKPEKSINPILATIKLLSENID
                     EKWTKDLYKLINQDNINGNLFGLNIEGKCGILSMVPTIINIVDGKLEVVLSVRYPEIL
                     TIEDIIKKFNLYMEQNNINKFELIGENLKQANYIDRNSKLVRSLHDIYIKYSGDLKND
                     VRVTSAGSYASEMNNSVIFGCEFPDGSFGNVHSANEFASLDRFITAIGIYAEAIITLC
                     NKI"
     gene            31511..33400
                     /locus_tag="KR231_000743"
     CDS             31511..33400
                     /locus_tag="KR231_000743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HBH0003150.1"
                     /translation="MITKKHAIIVKSLSNKDGYMTSNELAIKLDVSTKTIKRYIADLN
                     SVLSKYDLVIASSRGIGYKLSGSKNNIARAVKEANKYIDGFLDDSEESRMSNIICMLI
                     NRNYMSIEAMAEELNLSIAAINKLSSKLKRKLEKYDLVIKSKPYYGSYIHGEEINIRQ
                     LITDYAIKLDEKSKVKVFLDDISENDIHCIESILEKHLREKDTIISDKDFNLLLSKII
                     VSVFRSKRGHSNNINLMDTSYRFHNYYFIENLMKEISDKIGFKLIEDEVIYISNYSGV
                     IAYKGTQGRKNTSEIEERISTVISSALQDIFLISGSDYTKDDEFMVAISDHIKRFLNR
                     ARANVKSNNPLLHQIKEKFPIAFNLAVFLSNKLETEFNLKLDEDELGYIAIHFAASNE
                     RMKKNTSKKICIVCHYGIGTGQLISEKLKQNISDLSVVGVYPVRYLDMAISQDVDLIV
                     STVELKGYEKPVLYIENIFDDSLIENVNKAFYEKEERRKIISNMFDEKAFFSIKASTK
                     EEVIISLSNKLKERDFIEESSIKSIIDRENISSTEIGNLVAIPHTIVKGDKKSIIGVG
                     ILENPIIWDKQEVQLVFMVFFNTKEKHNFSIFKYLYNFIKDEGGVRGIIKICDFNKLM
                     ALIGN"
     gene            33415..33870
                     /locus_tag="KR231_000744"
     CDS             33415..33870
                     /locus_tag="KR231_000744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBH0003151.1"
                     /translation="MGTNIFNKEYVFLNVDAKSKVEVLKFISKKAKDLNLAEDESLVY
                     EGLMAREEQFTTNLGESIAIPHTKNDAIENPAVVVLKFNEDVVWNEGEDKVKLAISLL
                     MPGKSKENIHLKLLSSLSRKLINKEFKDSLLKSDNVEEISNLINEALGL"
     gene            33929..34246
                     /locus_tag="KR231_000745"
     CDS             33929..34246
                     /locus_tag="KR231_000745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIB"
                     /protein_id="HBH0003152.1"
                     /translation="MNKKLVALCACPMGLAHTFMAAEAIEQAAKALGYEAKVETQGAD
                     GVQNELTRDDILGATMIIHAVAITPEGMERFDGCEVYEVELQEAIKNAEGVIKEIEED
                     LGI"
     gene            34271..35533
                     /locus_tag="KR231_000746"
     CDS             34271..35533
                     /locus_tag="KR231_000746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIC"
                     /protein_id="HBH0003153.1"
                     /translation="MAIKKKVINSSGASTTGGNNVGKSTPSSPTQSKGNGKWKEISKH
                     IMTGISYMIPVLVMGGLIGALSQLIPYAILGLDPSVGIVDAMNSGEFTGFKLSLLNIA
                     QLMSNFGFTLFGFAIPLFAAFCANSIGGKTALIAGFIGGYIANKPVGVPQFVDGQWTE
                     VVPVASGFLGAILIAFIIGYFVKWLNKSIKVSHNWLAFKTTFLIPLIASLACMVLMIF
                     IITPFGGLINESMKNFLTAAGAAGEYVYATALAAATAFDLGGPINKAAGFVALGLTTE
                     NVLPITARTIAIVVPPIGLGLTTLLDKRLVGRRVYDRQFYQAGKTSIFLSFMGISEGA
                     IPFALERPGFVIPLNIVGSVIGAITGIILGAIQWFPESAIWAWPLVDNLFGYIIGIAV
                     GAIFIAVGNIFYRNKLIKDGKLVVDYID"
     gene            35638..36702
                     /locus_tag="KR231_000747"
     CDS             35638..36702
                     /locus_tag="KR231_000747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HBH0003154.1"
                     /translation="MDKIEKVREYFREYDIDGFLINSPTNKFYVGNLFSSSGYVFITK
                     ESQYIIVDFRYFEEIKRKSSLFNVVLMDKTRTHFDIINDICREQNIKEIGFEGNEVSF
                     DLYRSMSNKLSATLKSVDLSTLRETKNEDEIKYIKKACEIVDATFYHIVDFIKVGMTE
                     KQVENEIVRIIKDLGGQKESFDTIVASGLRGALPHGKASEKVIEYGDFVTFDFGAKYN
                     NYCSDITRTICMGTINKELEEIYNIVRKANEECIRVLRPGMTTGEIDKVARDIIGSYG
                     YANNFGHNLGHGVGIMVHEYPALAPESNEVLKEGMIVTIEPGIYVPSLGGVRIEDDVL
                     ITQDGCMRLTTSTKDLIVVS"
     gene            36756..37934
                     /locus_tag="KR231_000748"
     CDS             36756..37934
                     /locus_tag="KR231_000748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PatB family C-S lyase"
                     /protein_id="HBH0003155.1"
                     /translation="MYNFDDKPDRVSEKCRKWDLNIIRDKFGDIREDFIPMWIADMDF
                     KIPTEIENKFIEAVRRGVFGYTYCYDEFYDSVIGWQKNMHEVNVEKEWITLTYGTVST
                     LHYVVQAFCKKGDSIILNTPVYDPFESSAKKQGVNVICNTLDVVNDRYYINFDKLEVQ
                     IKENKPKLMMFCTPHNPSGRIWTIEEMTRVATICKENNVILVADEVHAEHIHYGTFNS
                     ILKIGKELLENVILLTSPNKGFNLGGLKTSYSIVINKDIRDKFRNKLKQNSITSPNVF
                     GIIGLITAYNECHEWLSGVNEYIKSNYELLETWVNKYNKIKLMKMESSYLAWMDISGL
                     GISASEFTDKLAIDTGVLLEDGSHFVKDGEKYVRINLGTQKENVIEALNRMDLFLKSL
                     "
     gene            complement(38125..39183)
                     /locus_tag="KR231_000749"
     CDS             complement(38125..39183)
                     /locus_tag="KR231_000749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD:protein FMN transferase"
                     /protein_id="HBH0003156.1"
                     /translation="MNKKKITFIFVILILALILFSFFRSSSQNTKYSKTSYYLGTVNE
                     VTVFNVKESKSDKILNECDSILRYIDNKMSTHIPGSDVSKINDNAGKKFVRVSDDTFF
                     VVKEAIQYSKLSDGYFDITIGPLSNLWAIGTDKAKVPSDSKIQKLLPLIDYKNIILDE
                     KNKSIKLTKENMKIDLGAIAKGYAADKIVAYLKSEDVKKGLVNLGGNIFTLENGKNDK
                     PFKIGIQDPTSKNGESIGNIETTNKSVVTSGIYERFIEKDGKIYHHMLNPFTGYPFEN
                     NLSSVTIISDKSINCDALSTSTFGLGLEKGMNLINKIDNVDAIFITKDKKVYLTKGIK
                     DNFKLTDKSFSIEKLNKQ"
     gene            39250..39621
                     /locus_tag="KR231_000750"
     CDS             39250..39621
                     /locus_tag="KR231_000750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NusG domain II-containing protein"
                     /protein_id="HBH0003157.1"
                     /translation="MKKKDILLILGILVVITACYGIINVINSKNAGNIEIYVDNKLYK
                     TVSINAKEEFKIESRGGYNIVKIHDKGVEIVDASCPDKVCVHTGFINKPSQSIVCIPN
                     RVSIKINTNEKNDNQEDIISK"
     gene            39658..40332
                     /locus_tag="KR231_000751"
     CDS             39658..40332
                     /locus_tag="KR231_000751"
                     /EC_number="3.2.2.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase"
                     /protein_id="HBH0003158.1"
                     /translation="MVNLGNDWDELLKEEFEKDYYLNLRKFLIEEYKTRQIFPNMHNI
                     YEALKHTSYKDTKVLILGQDPYHGDNQAHGLAFSVQPQVKTPPSLLNMYKELKDDLGC
                     FIPNNGYLMPWADQGVLLLNTALTVRAHEANSHKNKGWEIFTDRVISILSEREDPVIF
                     VLWGSNARKKVELIDTSKHYILEAPHPSPLSASKGFFGCKHFSKINEILKKLGKEPIN
                     WQIENI"
     gene            40581..41420
                     /locus_tag="KR231_000752"
     CDS             40581..41420
                     /locus_tag="KR231_000752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="G5 domain-containing protein"
                     /protein_id="HBH0003159.1"
                     /translation="MNFKKLSNAKVSVMAVVLSVGILSGYSALNKQVTLVVRGEERTI
                     STFSSNVGDLLESQNISYDSNDIVTLDENTKLSNGDKIEVIDVKEKTVVETKDIPFEV
                     TVVEDGSLLKGDSKVKEEGKSGKSELIYKETYHNGKKVEKEFVKKVVKAEPVNKVVSK
                     GTKVEMQVASSRGESSRRMASSSSSSSSSNNGKNMRVVATAYTGHSITATGTKPKWGT
                     IAVDPKVIPYGTKVYIPQFDMVFTAEDCGGAIKGNKIDIYMNDSKTVYNWGRKTIDIR
                     ILK"
     gene            41664..41760
                     /locus_tag="KR231_000753"
     tRNA            41664..41760
                     /locus_tag="KR231_000753"
                     /product="tRNA-Sec"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:41698..41700,aa:Sec,seq:tca)
     gene            41915..42622
                     /locus_tag="KR231_000754"
     CDS             41915..42622
                     /locus_tag="KR231_000754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA threonylcarbamoyladenosine dehydratase"
                     /protein_id="HBH0003160.1"
                     /translation="MENNFTTRTSFLVGDDGIKKLNNSNIIVFGVGGVGSFTVEALAR
                     AGVGNITIVDFDDVDITNINRQIPALHSTVGRYKVDVMEERILDINPNINIKKIRSLY
                     NKDTSDEILTERYDYVVDAIDMVSSKIHLIETCEKKGLKIISSMGMGNKLDPTKIVVT
                     DIHKTSTCPLAKVMRKELRDRGIKKLKVVYSTEQPIELKKKVMNGRKVTPGSVSFVPS
                     VGGLIIASVIVNELLGQ"
     gene            complement(42764..43600)
                     /locus_tag="KR231_000755"
     CDS             complement(42764..43600)
                     /locus_tag="KR231_000755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HBH0003161.1"
                     /translation="MRNKIFLSILIIISLLIGCDKKSLLSIHMIDVGQGDSILVQTPT
                     NKNILIDGGDEDSENIIISYLRQKRIKTIDIIIATHPDSDHIGSLDNIIKKFNVNSIY
                     MPEQSTDSKAYQNLINSCTDKNLSIQHLYKNDVLNIDNNINIYVLSPSYIQEESNLNS
                     IVFKLTFNDNSFLFMGDAEEENEKEILHSFKLNNINFIKIGHHGSNSSSSLEFIKKIS
                     PDIAAISCGYKNQYGHPHREVINNLKQNHVSIYRTDRIGDIVFYSDGEIIFTKYNYEI
                     DT"
     gene            43788..44693
                     /locus_tag="KR231_000756"
     CDS             43788..44693
                     /locus_tag="KR231_000756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2156 domain-containing protein"
                     /protein_id="HBH0003162.1"
                     /translation="MFFKDIELNSKKELDPYFDLVDYEACEYCFSTLYMWQHVYKTGY
                     YIGEDFAVLVGEYEGDSFSILPLAKKDKLPEVVDFVLEYFSKNNKKIYLRGITTEVVE
                     FLKEKYPGRFEYIEERDLFDYIYDAESLRTLAGKKNQKKRNHINYFLKEYAGRYEAKL
                     LDKENFDECLVLMKEWESNKEENNEFDESMDDELIGIKKIFNHYDILKDKVKVFGVYV
                     DGKLEAFSIGELLNPNMALIHIEKANPDIRGLYPFINQQFLVSEFKDVEFVNREEDLG
                     IEGLRKAKLSYHPCRFVEKYSVREA"
     gene            44702..45886
                     /locus_tag="KR231_000757"
     CDS             44702..45886
                     /locus_tag="KR231_000757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBH0003163.1"
                     /translation="MEIRYAKEEEIESIKDIWSYCFNDTESFMKYYFNDKYKSENTVV
                     ALDEGKIISSLQLNQYKLLLNSKVYNTSYVVGVSTLPEGRGAGYMNKVMKFTLNELYK
                     KGQLVSILMPIDYRLYRRFGYEHCYDQIEYTINTDDLKNFKSSGKMIKSNLSQIDDLI
                     QIDRTFLNEVNGNVLKDEHYYENLFKEIQSEDGFLYIHEGNEKDGYIVYFLQEDKMFV
                     RELFYKNIDALKSMLKFIYNHNTQCKIVTISTPTIDKIRFILDNPKDSDIKIKPFMMG
                     RVINVKKFIEDIDIEKDINSSFNLLIEDKFIDENNGLFKISIQNKKVSVEQLDKKGAE
                     KPQEDFDIKLDINTLTQLSFSYIDVNEAIFLNDIKDVSEETLETLNCIFSKKNNYINE
                     YI"
     gene            46001..47302
                     /locus_tag="KR231_000758"
     CDS             46001..47302
                     /locus_tag="KR231_000758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComEC/Rec2 family competence protein"
                     /protein_id="HBH0003164.1"
                     /translation="MGVIIIQIRRPLLIILMFVVAISFIITNNTKNDEELNDKIITIQ
                     GVVKGKIEKKRYNQYKVGVFLINDYTKNKNLKIGQKVNITGKFKSLDKMKYDDFDYGR
                     YIKSTGYKGIVYINNYKIIDKNKLYSLIGEIKFYISKTYRYLYKKNSDFINSILLAEV
                     ENLTEEQKEIFTRTGTSHVISISGLHTGILCVIISFLLRGINKLYKLLILSIFITLYC
                     IMVGASPSIIRSIAFVMIFYLSIFIDRKKDGISALSLIGIILIMNNPYVIYNVSFQLS
                     FLATLSILIFYNKINSIIKLSMVSLTISSNILTLPIIYYTFKGIPLLSIIGNLIIVPF
                     VGVIMYLSIASLIVFKVSVVIAKIISFFNSTFIESIFFLLEKISNLSFAYINIENPKF
                     YIVVIYYIGVFFYIFYIEGKEIKEQENELQGYYKECKREKL"
     gene            47256..48299
                     /gene="holA"
                     /locus_tag="KR231_000759"
     CDS             47256..48299
                     /gene="holA"
                     /locus_tag="KR231_000759"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta"
                     /protein_id="HBH0003165.1"
                     /translation="MNYKDIIRNVKEKNFEKMYLFYGREYYLIENAIKAFKDSLNEGM
                     LDFNLDIIDGKEIVLNQLISSIETLPFMDDRKIVIIKDFELLKGKKKNFTDSDEKYLI
                     EHLDNIPDTTTIVFVVYGDVDKRKSLVKKIGNNGIVFDCDKLSDMDLFKWIKKSFALN
                     DVIIDNSQIMYFIEQEGYRDKSSEKTLSDLENEINKISSFVGKGNNVTNDVIDKLSQK
                     KVENDIFKLIDYIGEQNASNAMKILNDMIQEGESVLGIFSMIARQFKIIMQVRQLQLD
                     GYSTKLIADKLKMHQFVVGKALKQTKNFSDDIIVEILNYILESDYKIKTGLIRDTLAV
                     EMLVSRYCKREAI"
     gene            complement(48486..48752)
                     /gene="rpsT"
                     /locus_tag="KR231_000760"
     CDS             complement(48486..48752)
                     /gene="rpsT"
                     /locus_tag="KR231_000760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S20"
                     /protein_id="HBH0003166.1"
                     /translation="MANIKSAKKRISVIEKKTALNRVRKSQIKTAIRRFEDAVAAGNR
                     EDAVAKFQYAQKRIYQVASKGTIHKNAAARKVAKLAQKLNGMNA"
     gene            49348..49869
                     /locus_tag="KR231_000761"
     CDS             49348..49869
                     /locus_tag="KR231_000761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBH0003167.1"
                     /translation="MDIAKLILNPARLRILQYIRLYGSVRTSDIVKYLNDIPRATVYH
                     HVKILEENNMIEVIKENRVRGTIEKVYALKEYTTSMEGETFVALSTAFYVGLMQEMNE
                     YFSRKEQDHKKDNVFFSSALLYMSDNEYENLLKSIADLLKPYIEQKPKSNLKLRKLSI
                     ISSPPVADNDKTK"
     gene            49903..50679
                     /locus_tag="KR231_000762"
     CDS             49903..50679
                     /locus_tag="KR231_000762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HBH0003168.1"
                     /translation="MKFHEFGNKNRPHIMLIHGGGNAWWNYLRQAEVLSNKYHVILPT
                     LDGHGEEYETTYISTEDTADKLISYIDENCSGHLFALCGVSLGGQIVMELLSRKPNIT
                     KKAIIDGSICYPRPLMARFCIAGIRFFGGLLFSEKACRFQIAMMPKLLPENMQYPDEI
                     KAYYMTDMPHVRKETFYNMYRTYMMNYTLKENVKKTTAQVMYWYGEKEMKCVKKSAKL
                     FQSYVPSCEIYEAKSYNHGYLSLYLPNEWLEIAEPFFQKE"
     gene            51021..51974
                     /locus_tag="KR231_000763"
     CDS             51021..51974
                     /locus_tag="KR231_000763"
                     /EC_number="3.4.24.78"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GPR endopeptidase"
                     /protein_id="HBH0003169.1"
                     /translation="MISVRTDLALEASEMCEKSQEGSSIPGVKIETKELENCIVTKVE
                     VIDRQGAEIMNKDIGKYITLESNLMKFDDDESREEMISYLKEELVDIFGQDKNKKTLV
                     IGLGNRNITSDALGPKSVSKTLVTRHLFKNYNKDYDDDFTEVSALSPGVMGVTGIETS
                     EIVKSLVEKVKPDRVVAIDALASRKMERVNSTIQISTAGISPGGGVGNTRKSLTKETL
                     GVDVIAIGVPTVVDAATLTIDVLDMAIDNLIAQSEETESFYEMLKKLKEEEKYHLIKD
                     SLDPYDKNLIVTPKDIDDTIENLSIIISEGLNRSLHPGRLV"
     gene            51992..53011
                     /locus_tag="KR231_000764"
     CDS             51992..53011
                     /locus_tag="KR231_000764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage II sporulation protein P"
                     /protein_id="HBH0003170.1"
                     /translation="MFKKCIKVVTLTFILVCILPGKSLALNQDDFLKFLVNSSYPEAK
                     VEGNDTENKKNNKNKETSKENKEESKEGNTKSKDASKVDNKKESEKEYIKLYVGKENV
                     PDIESKNSDTTETNTTSSSDYKDDLRVTKENPRILIYHTHGCETYSNSPDGNYHSRDK
                     KNSVMEVGSALTSALDSKGWGVVHTTKYHDYPSYNNSYASSLKTIQSILPKYNSVDIA
                     IDLHRDARDLTNPATKEKDHLKYTTMINGERVSKFFFVVGGKNTNRKQLRALAEDITA
                     FAEKKYPGLVSPIVEKDYARFNQFAVKNHMLVEIGNNATSVEESKATTKYLAEILDEY
                     FKQKN"
     gene            53042..53293
                     /locus_tag="KR231_000765"
     CDS             53042..53293
                     /locus_tag="KR231_000765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0003171.1"
                     /translation="MSRLEKNIESKSKLRKYKYIMRILFLITMIICTSVCVFIVDSNA
                     KSMLGMKQYDFPSIKFDITKFDFDIPNFDIHEIIKKFNK"
     gene            53575..55380
                     /gene="lepA"
                     /locus_tag="KR231_000766"
     CDS             53575..55380
                     /gene="lepA"
                     /locus_tag="KR231_000766"
                     /EC_number="3.6.5.n1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor 4"
                     /protein_id="HBH0003172.1"
                     /translation="MDNKQSRTRNFSIIAHIDHGKSTLADRLIQQTGLVSERDMKSQL
                     LDNMDLERERGITIKLQNIRLMYKAKDGNEYYLNLIDTPGHVDFNYEVSRSLAACEGA
                     LLVVDAAQGVEAQTLANVYLAIDQDLEILPIINKIDLPSARPEEVKNEIEDLIGLDSS
                     EAPLISAKTGLNIEDVLEDIVKNVPPPKGDNEAPLKALIFDSYYDAYKGVVAYVRVFE
                     GTVKKGMTIKMMNTNKKFEVTEVGVMAPGQTELSELSAGDVGYIAASIKDIRSCRVGD
                     TITDSNNPTEEPLPGYKKATPMVYCGIYPGEGEKYENVRDALEKLQVNDAALEYEAET
                     SAALGFGFRCGFLGLLHMEIMQERLEREFNLDIITTAPSVIYRVTKMDGEVVMIQNPA
                     NLPEPSEIKMIEEPIVKGDIIVPKDYVGVVMELCQERRGNMLNMEYIDDRRVMLHYDL
                     PLNEVVYDFFDALKSRTRGYGSLDYEVKGYVASTLVKLDILINKEQVDALSFIVHETR
                     AFPRGKAMCEKLKGEIPRHQFAIPIQAAVGNKVIARETISALRKDVLAKCYGGDISRK
                     KKLLEKQKEGKKRMRQIGSVEVPQKAFMSVLKLDE"
     gene            55529..56866
                     /locus_tag="KR231_000767"
     CDS             55529..56866
                     /locus_tag="KR231_000767"
                     /EC_number="2.7.7.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CCA tRNA nucleotidyltransferase"
                     /protein_id="HBH0003173.1"
                     /translation="MINIEIPKKVDYIIKELEKNGYEAYIVGGCVRDCLLERVPNDWD
                     ITTSARPEVVVELFEKTIPTGIQHGTVTVMIEHEPFEVTTYRIDGNYSDGRHPDSIEF
                     TNNIVKDLSRRDFTINSIAYNSKTGLVDPFNGYEDIQNKYIRCVGNPVDRFEEDALRM
                     LRAVRFSAQLNFKIAEGTKQSIHKKADLIKNVSIERIQTEFNKILVSDSSKLNLLKST
                     GLLKFIIPEICELEDVTQHNPYHIYDVQKHTLIATEVIEDELYLKLTMLFHDLGKKVT
                     KTTDKNGVDHFYTHSRESVKIAKKILKRLKYDNYTINKVLILIQYHDYRIEPKRKIIK
                     KLLNKLEDVELFEDLIKVNWADTLAKNPKYAKQKILNLIECEKEFKHIINQKECFNLK
                     DLAINGKDLISIGIKPGKDIGYILNKMLEIVINNPELNEKEILKEKALNIYTF"
     gene            57099..58412
                     /locus_tag="KR231_000768"
     CDS             57099..58412
                     /locus_tag="KR231_000768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HBH0003174.1"
                     /translation="MHTQLQKTIGLSAALSTVVGMVIGSGVFFKPQAIYTTTNGAPGL
                     GIIAWLLGGFITITAGLTATEISAAIPKTGGMMIYIEEIYGEKLGFLTGWMQTVLFFP
                     GTSAALGVIFAQQASELLGMSPNNMANVLPIAIGVILFLALLNIIGSSLGGKVQTVAT
                     IGKMIPLILIIVFGFIKGQSSEVLNPFVGDGVNASNALGQVLIATLFAYDGWINVGAI
                     SGEMKSPEKDLPRAIVGGLSLVMAVYIIINIAYLWVVPASELATVTSPATLVATRLFG
                     NIGGKVITVGILISVFGTLNGYLLTGSRIPYTLAEMGTLPASKTLLKVNSGGSPVNSI
                     LLITVLACVYALSGQFNLLTDLTIFSIWVFYVLTFIGVMRLRRQKPDLHRPYKVPLYP
                     IIPIIAILGGLFVIINQILTSTVISLGGIFITLLGLPVYYYMKKR"
     gene            58584..59759
                     /locus_tag="KR231_000769"
     CDS             58584..59759
                     /locus_tag="KR231_000769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxygen-independent coproporphyrinogen III
                     oxidase"
                     /protein_id="HBH0003175.1"
                     /translation="MLGLYVHIPFCVKKCKYCDFNSYKMDIDSKKRYIEDLKIEMELY
                     SNKLYKDNKYKNKECCSLNKNDKITSIFVGGGTPSILTSDEIREVFISIKEMFDIDEN
                     AEITIECNPGTLTLEKLKTMKEIGINRLSIGLQAIQEKHLNFIGRIHTYEEFEKNYKD
                     ALSVGFKNINIDLMYSLPNQTLCDWKETLEKVVHLNPTHISAYSLILEEGTELYNMYE
                     SNKFELIDENVDIEMYEYTINYLKSKGYNQYEISNYSKEGYNCEHNILYWECEHYIGI
                     GAGASGYINENRYNNVESLEDYHLSLVKREKPIQENEILSEKDMIEEKIFMGLRMNKG
                     IKFEDFKKKFGIDFREKYNKQIEMLLARKLINQSFEGIQLTQKGREISNSVFIEFME"
     gene            59862..60881
                     /gene="hrcA"
                     /locus_tag="KR231_000770"
     CDS             59862..60881
                     /gene="hrcA"
                     /locus_tag="KR231_000770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heat-inducible transcription repressor HrcA"
                     /protein_id="HBH0003176.1"
                     /translation="MELNERKLNILKAIVKDYIETAEAIGSRTISKRHDLGVSAATIR
                     NEMADLEELGYLIQPHTSAGRVPSEKGYKLYVNSLMSKSELDDNDKILIEQCMNHNIN
                     HIKELIHETSKLLSQLTNYTTVAVTKSLINQSVIKHIQLVAMNDNNILLIVVTDKGDL
                     KKANLTTNVYLDQSKLNLISDNLTRKLLGKSITDLDDNLIAFIKYEISEYSGLIDELL
                     NALNSNMKEEDFSLSLNGATNIFSYPEFNDVLKAKSFLNMLEKKETIADIIKSKGIQK
                     DNLNIIIGSDNDCELAQDCSIVTATYNVDRDLVGRISFIGPTRMDYARIYSIINYMSL
                     LINRK"
     gene            60911..61531
                     /gene="grpE"
                     /locus_tag="KR231_000771"
     CDS             60911..61531
                     /gene="grpE"
                     /locus_tag="KR231_000771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide exchange factor GrpE"
                     /protein_id="HBH0003177.1"
                     /translation="MDKKNEQQEVREENDTSINQESETQVELEEEVVNEECETSSEKT
                     DEKEVDDENVTDINSKLAEKKLQDELDELNDKYQRLQAEYANYRRRTQQEKETIGVFA
                     NEKIITELIPVIDSMERALDACEDKEDTMYKGISLVHKQLIDTLVKFGVEEIEAESKE
                     FDPNLHLAVMQESVDGVEANQIVMVLQKGYKLGTKVVRPSMVKVSC"
     gene            61623..63470
                     /gene="dnaK"
                     /locus_tag="KR231_000772"
     CDS             61623..63470
                     /gene="dnaK"
                     /locus_tag="KR231_000772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000034699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaK"
                     /protein_id="HBH0003178.1"
                     /translation="MGKIIGIDLGTTNSCVAVLEGGEAQIIANSEGMRTTPSVVAFTK
                     DGERIVGEPAKRQAVTNADKTITSIKTHMGTDYKVNIDGKSYTPQEISAIILQKLKSD
                     AESYLGQTVTEAVITVPAYFTDAQRQATKDAGRIAGLDVKRIINEPTAAALAYGMDKL
                     DQEKKILVFDLGGGTFDVSILEIGDGTFEVLATAGNNRLGGDDFDQIVIDYLAEEFKK
                     AEGVDLRNDKMALQRLKEAAEKAKKELSSTMSSNINLPFITATAEGPKHLNIDLSRAK
                     FEELTRGLVEKTMEPTKTALQDAGLSTGDIDDVLLVGGSTRIPAVQEAVKKFIGKEPH
                     KGINPDECVAAGASIQAGVLAGDVKDLLLLDVTPLSLGIETMGNVMTKIIERNTTIPT
                     KKSQIFSTAADNQTAVDIHVLQGERSMAYDNTTLGRFQLTDIPPAQRGIPQIEVTFDI
                     DANGIVNVSAKDLGTGKEQKITITSNTNLSESEIEQKIKEAEMNAEADKQKKEKIEAF
                     NQAESTIYQTEKTLNELGDKISSGEKEDIEKAIADLKAVKDNQDATAEELKKATDEVM
                     TKFQKVSQEMYQKAAQEQQAAQGAEQAQDNGPKDDNVVDADFKEVDEDK"
     gene            63681..64835
                     /gene="dnaJ"
                     /locus_tag="KR231_000773"
     CDS             63681..64835
                     /gene="dnaJ"
                     /locus_tag="KR231_000773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaJ"
                     /protein_id="HBH0003179.1"
                     /translation="MSTKRDYYEVLGISKGAEAQEIKKAYRKLAMKYHPDRNPGDKEA
                     EEKFKEINEAYEVLSDDTKRKTYDQFGHDGLNGQGGFGGQGGFGGQGFGGFEDMFGDI
                     FGDMFGGSFGGGRARRRGPQRGADIRQSVTISFEEAAFGKKMSIKVNRSEECEECNGT
                     GAKPGTSKKTCSTCNGTGQVRTVQRTPFGNIASSRPCSACNGTGEVIESPCSKCHGTG
                     NTRKVKTIEVDIPAGIDDGQMIKLSGQGEVGEKGAPRGDLYIVVNVKSHPLFTRDGND
                     IYFEMPITFVQATLGDEIEVPTLDGKVKYSVPEGTQTGTVFRLKEKGIPRIRGNSRGD
                     QYVKVVVEIPKKLNDKQKELLREFAKECGSNVHEKKKTFGQKIEDMFKKK"
     gene            65801..66736
                     /locus_tag="KR231_000774"
     CDS             65801..66736
                     /locus_tag="KR231_000774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HBH0003180.1"
                     /translation="MYYIGVDIGGTGIQAGVVDNYGKIIFRSECKTVIEKGFEGILND
                     IKIMIYKLLEDNKLTMSDIKSIGFGVPGFINKEGLVTCVNLKWNKKAFNKELKKRFPD
                     VEIHGENDATVAALGEAKFGSMKGANVGVLYTLGTGVGGGIVINQKVFSGAHGLGSEI
                     GHQIIGENYFNCNCGNNGCVETFCSATAIIKYSQKLIEEGEKSRILDLAEGNLENVNA
                     KMVFDAYRENDLVAIKVINRFKEYLAKTFANTINSLDPEIISIGGGISKSSDIILDGI
                     EGLVRKFVLYKTEDIATITCATLGSDAGIIGAAFL"
     gene            66772..68145
                     /locus_tag="KR231_000775"
     CDS             66772..68145
                     /locus_tag="KR231_000775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBH0003181.1"
                     /translation="MGKTNARRTLFLIAIGSGTMLNPLNSSMISLALHSIQNDFHISF
                     TTVSWIVSAFYLASAIAQPVSGKIGDLIGRKVLFLSGLMLVILSASIVPLVQSFFILI
                     FIRVIQAIGTSTLYPSGVALIQNNIKERQSSALAVLTIFASTTAGLGPTLGGLLLDLG
                     GWHAIFLVNIPVVLVSICLGYFLFPKEVKEKKSIKETLKNVLSRLDIIGILLFSIAMI
                     FILLFLLSMKESFNLEQLVFGIILMCLFIWHELRTKLPFIDIKLFVSNPKLSKVYLQF
                     IILNFFNYILFFGLPSYFQDALHYSAKSTGLFMLFMSGIGIFISPLTGKWIDKSGTRF
                     PLVTSSIFMFISAVLLSVVFIHIPVIGKGIILSLAGISYGVGNVALQSSMFEESPRDS
                     IGTASGLFQTSRYLGSILATVLLGMVFEVNITSEQFQILGYVMVVLGTISFLLNFILK
                     KELRKVE"
     gene            complement(68333..69100)
                     /locus_tag="KR231_000776"
     CDS             complement(68333..69100)
                     /locus_tag="KR231_000776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBH0003182.1"
                     /translation="MEELKDFLERQLNKKINIYPYENQKLDASSHLVTFNNAIYVIDF
                     LDKNNLDNLKGNFYLIYQSHIDFEYLKNIFYNLFEDINIIQHNGFFIVNSKYNLDINV
                     TTQNIIETETYQSTYIFYLGELDSKADFDFRLQLCSDLLPHIIKDNAENKFLNLFDLI
                     RYKTLDLINEDNILNKLIDFNKIKSIDEELLYTGIKFINNDLNISKTSTSMFLHRNTL
                     VYRLEKINEILGFDLKNFENAMIFYLSVKSYFLYKKI"
     gene            complement(69130..70239)
                     /gene="ugpC"
                     /locus_tag="KR231_000777"
     CDS             complement(69130..70239)
                     /gene="ugpC"
                     /locus_tag="KR231_000777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003242648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sn-glycerol-3-phosphate ABC transporter
                     ATP-binding protein UgpC"
                     /protein_id="HBH0003183.1"
                     /translation="MSEVILKNISKLYSNGFNAVKNINIDIKDKEFIVLVGPSGCGKS
                     TTLRMIAGLEEISEGELYIGDKLVNDIEPKDRDIAMVFQNYALYPHLSVYENMAFALK
                     LRKLPKDEIDKKVKEAAKILDLLPLLNKKPKTLSGGQRQRVALGRAIVRNPKVFLMDE
                     PLSNLDAKLRTAMRTEITKLHQQLGTTFIYVTHDQVEAMTMADRIVVMKDGVVQQIAT
                     PQDVYDYPANIFVAGFIGAPQMNFIDVILIEENDEIYAQNEHIKLKLNKEKHYDLIKD
                     NYINNEVVIGIRPEDIHVEDTFIKSNPDTCFKSRIEIKELMGAETYAHLKLGENTITI
                     RFDSKNRINVGDDLTLSVDNSRVHIFDKETTLAIR"
BASE COUNT        27585 a         7681 c        12102 g        22970 t
ORIGIN      
        1 agattttggg taaataaaat aatataaaat ataaatttta ataaaaataa taaagtatat
       61 attattgctt taataagaat gtaaaaaata tttttaaatt atcatttaat gtaatttaaa
      121 tgaattgaag atatatgttt attgtatgca attgttgtat ttttaggttt tttgtgatta
      181 attaaaaaat tataaaaatc gtttacatgt tgatttttaa aaaaaaaaga tatagaatta
      241 tatagaaagt aataaacaaa aattggattt acgggagtgg aatgaaatga tgaatgttac
      301 cttaacagat gtaaaagagg ctagagagac cattaagaac atagtaaaaa gaactgactt
      361 acttgaaagt gttaaactta gcgaaaaaac aggagcaaat gtgttctata aatgtgagaa
      421 tcttcaaaaa acaggttctt ttaaattaag aggagcttgt aacaaaatag cgagtttaac
      481 agatgaagaa aaggcaaatg gagttatagc ttcaagtgca gggaatcatg ctcaaggagt
      541 tgcattggga gcaaaaatga ctggtataaa atctacaata gtaatgccag caactgcgcc
      601 tttagcaaaa gttagtgcaa ctaaaggtta tggagcagaa gtagttttaa atggtgcggt
      661 ttatgatgat gcatatgcaa aagctgttga aatacaaaaa gaaacaggag caactttctt
      721 acatccattc aatgataagt atgttatagc aggacaagga actatatctc ttgaaatttt
      781 cgaacaatta gacaataaag ttgatactat actatgccca gttggtggag gaggaatcat
      841 ctctggtgtt gctgttgcag caaaagcatt aaatcctaat gtaaaaatag tcggtgttca
      901 aactgcaaat ataccttcaa tgaaagagtc aataaaaaat ggaaaagtaa caacagcatt
      961 taatgatact acaatagctg atggtatagc tgttaaaact ccaggagatt taacttttga
     1021 aataataaat gaattggttg atgaaatagt agtggttgaa gagacagaaa ttgcagaatc
     1081 aatattattt atgatggaaa gtcaaaaaat agtttcagaa ggtgctggtg ctgtatgtac
     1141 agctgctata ttaagtggta agtatgtacc agcaaaagat gaaaatgtag tttgtataat
     1201 atctggtggt aatatagaca taaatacgtt atatagaata ataggtgttg ctttagctaa
     1261 agaaggaaga agatattcat ttagtacaat tatggaagat aagccaggaa actttgctga
     1321 gttaactaga ataataagtg agaatggtgg aaacatttta agtgctaatc aaggtaaatt
     1381 atcagcaggg gaagctctag gaaaacaaag tgcggaattt atattagaga caatagatta
     1441 tgaccatata gctagaataa agaaagctat agaagaaaaa ggttttaaaa ttatagaatt
     1501 ataataaaaa gtgtatataa tatacaagaa aaatagtata atagtgtatg aagatacatt
     1561 ttatgtgtat tagattaacg aattaggagg attttaaaat gaaacatgaa gtaatacata
     1621 ctaatgatgc accagcagct ttaggaccat attctcaagc tataaaagct ggaaacttgt
     1681 tatttgtatc tggacaagtt cctcttgtac cagagactat ggaagtagtt gaaggagatg
     1741 tacaagctca aactgctcaa tctttaaaaa atcttaaagc tatattagct gaaagtggag
     1801 ctgatttttc aaatgtagtt aagactacag tatttataaa agatatgaat gaatttgggg
     1861 ctataaacga agtttatgct gaatattttg gagaaaataa accagcaaga gcttgtgtag
     1921 aagttgctag attaccaaaa gacgttaaag ttgaaataga agtaatagct gtattataaa
     1981 aatacaatat ttttaatttg aaaaggctga aaaactatat tctagtgatt cagccttttt
     2041 ataaaaaaat aaatcacaat aaagaacatg ataaatattg tcgaattaaa aaataaaatt
     2101 aaaataaata ttgcaatatt tttgagaagg ttttataatg agtatataat ttgaaacgtg
     2161 taactattaa attaggcatg agttcttgga tatttttatc ctgaggattc atgccttttt
     2221 tgtattgaaa ttcaaaaatc tatttaataa ggaggaagta ctgtgttaaa ttttttcaag
     2281 aaaaataaaa gctataagtt acatgcagta gtgagtggta acagcattaa tattgagaaa
     2341 gtaaacgatt ctgtgttttc aaaaaagtta atgggagatg gagttgcaat tattcctaat
     2401 agtaatgttg ttgtagcccc ttgtaatggt aaagtaactg tgcttacaga atcaaagcat
     2461 gcctttggta tggtctcaga tgagggtgtt gaaatattag tccacatagg aattgataca
     2521 gttagtttac agggtgaggg gtttaaaaat gaagtgtctc aaggagatac tgttaaaaaa
     2581 ggtagtccaa taataagttt tgaaagagaa aaaataaatt ctcagggaat tgattgtaca
     2641 acaataataa ttgtattaaa tcatagcgaa ttttcagaaa taaattgcat ggtagaaaat
     2701 gaagttgttg cagggcaaga tactgttatt gaaattatga aataatagaa agggattaat
     2761 tcaatatgag agtagtaaaa atctttaata ataatgcatt atctacagta actaatgata
     2821 ggaaagaagc tattttacta ggtcttggta taggttttaa taaacgtcca ggagataaag
     2881 ttaatgaaga taaaatagaa aagatttatt atgttcaaga ccacatgcaa acaaaatttt
     2941 tagaattatt aaaaaatgtt agtccagaag tgatggatgc ttcacaacaa attataagtc
     3001 ttataccagg aaatgaggga aaatttaata ataaagggat attatcttta gtggaacata
     3061 ttagttttgc aatagataga atgaaaaata atgttttttt acctaattta atgcttttgg
     3121 atataaagat gatgtattca aaagagtttg aattaggagt aaaagcttta gaaattatat
     3181 atagagtatg tcatatccat ttgcctgaag atgaagcagg ttacatagct ttacattttg
     3241 tcaatttaca atcaaatgat aatttggcat atgatacttt aaaatttgta aaaggtagta
     3301 ttgatttgat taaagaatgt tatggattag aattagacga atcgagttta agtacattac
     3361 gttttagaac tcatcttaaa tttcttgctc aaagaatttt taagaatgaa atttgtcagg
     3421 atgataaaat gattgaaatg tatgattatt taattaacaa tcatcctaaa aataaagaat
     3481 atttagaaaa gttaaatgta tatattgaaa aggagtttag gtataaatta gataaacctg
     3541 aaaaaattta tctactacta cacctaacaa aaatcttata agaatgagat gaattagtaa
     3601 tagaaatata tataatttta gggggggata agattgaaag aaaaactact tggaggactg
     3661 gaaacatttg caaaggcaat ggttcagcca ttaatgtatt tatcgagtgc aggaatatta
     3721 atggtggtag gtgtactact tacaaatgat atgttattag gagtacttcc attttttaaa
     3781 tgggagccaa ttcaaatatt tggaagccta atttataact gtataatggc tattattaat
     3841 aatcttgctg ttatatttgc tataggtatt cctgctgcac tagcaaaaaa agagaagcac
     3901 aaagcagcgt taataggatt tatgagttat ataatatacc ttacagcttc caacactatg
     3961 ttaacatcac taggtcaact agcaaaagaa agcaagatgc ttggactgat agggactgga
     4021 caagctacta ttttaggtat tcaagttgta gatacaagtg tatttggtgg aattatttta
     4081 gggtatatag ctggatatgt atttaatcgt acaagcaaca aaacatttaa aggagcttta
     4141 cagatatact cgggagcaaa ttttagtttt atatgcatgt tctttgtatc cattttaatt
     4201 ggagttgtga gtaactttat atggccatta gctcaacaag gaatagcttc tcttgcaaat
     4261 gtcatcaaag atacaggtac atttggttta ttcttatatg gttttttaga gagaatatta
     4321 gtaccaactg gacttcatca tttaatttat acaccatttc agttttctga tttaggagga
     4381 gtgcttaaag ttggtgcaga tacagtttca ggagcctatg ctatagttat gacagaaatg
     4441 aatttaccag ttgagcgttt ctcagatagt atatactaca tggcaactgg atttacaaag
     4501 atgtttggtt atataggtat aggagctgcc tttatttata ctgcatataa gcaaaataag
     4561 aagaaggtta aggcaacgat tattccacta ataattacgg cagtattagc ctctgtaaca
     4621 gaaccattag actttatgtt tgtattctgt gcaccacttt tattctttgt acatgcagtt
     4681 atagctggtc tttttatagc tttattaaaa atatttgatg ttactgcatt atgtggaggg
     4741 aacttattag tatcagttat aatgaatact acagtaggcg tagaaaaaac acactggcca
     4801 gtaatgatga tattaggact tgcacaaatt attgtatatt ttgtagtatt tagtttttta
     4861 attaagaaat ttaattataa aactccaggt cgtgaagatg agagtacagc tacaggcgaa
     4921 gaacaatcaa aacaacttaa tttagatgca gggatagaaa atataattga tgggttaggc
     4981 ggaaaagaaa atattaatac agtagaaaat tgcatcacta gattacgtgt taatgtaaaa
     5041 gatgaaagta agattaatga agatataatt aatttaacgc caaatagcgg gattgtaagg
     5101 aaaggaaaag atatacaaat aatttttgga cttcatgtgc atgaggtaag acgtgcagta
     5161 gaagattttt tagaagctta ttaaagatat atatttatat agcaagggta aataacagct
     5221 ttaagtgctg tttactattt attaaagata catataattt atagaggagg aataattatt
     5281 atgattatta ctattgttgg tggaggaagc acatttactc caggtattgt taagtcaatt
     5341 gcattaagag aaaaagagtt agagcttgag gaaattcgtt tatttgatat tgataaaaaa
     5401 cgtcaagata aagtagctgt agttgtcaac tggatactaa aagaagatgt taaaacagat
     5461 gttaaactaa ctgtaactaa ttgtgaaaaa gaagcgtata cagatgctac atttatattt
     5521 gcacaaatgc gtgttggtaa atatgaaatg cgtgagcagg atgaaaaaat tccattgaaa
     5581 tatggttgtg taggtcaaga aacttgtggt tgtggaggga tggcatacgg actgcgtaca
     5641 atacaaccaa tgataaaggt tattgatgat gtagagaaat atgctaaaaa agattattgg
     5701 atattaaatt actctaatcc tgctgcaatc gtttctgaag cttgtcgtaa gttaagacca
     5761 aatgcaagga ttataaatat ctgtgatatg ccaatagcta ttatagatat gatagcgggg
     5821 tcattaaata tcaatgacgt tcataatata cgctatgatt attttggtct aaatcatttt
     5881 ggctggttta cttcaataga ttataaacat agagacttaa tggaagagat taaggaatac
     5941 ataaaagaaa ataaaatatt attaccaaaa tcttatatag aaaacttaaa taaaagtcgt
     6001 agtacaggaa atcgccatgc tgtaagtagc tggatacatg tttgggaatc tgtttataca
     6061 atgttagaaa gcttcccaaa atatctgcca aacacttatt taacatacta tcttttaagt
     6121 aaagaaacag tggaacattc aaacataaat cgtactcgtg caaatgaggt tatggaaagc
     6181 cgtgaaaaag acttatttga aggtgtgaga cattacttag aaactggaga aatttctgaa
     6241 aaagcatttt atgcaggttc acatggagat tggattagtg atttggcagt ttcaattaaa
     6301 aatgatacac gtagtcgttt tttagttata actgaaaatc gtggagctat accaaacatg
     6361 ccatatgatg caatggtaga aattccagca tatattggta aagatggtcc agaagttatt
     6421 gctcgaggtc caatacctct atttcaacaa ggattaatga tgcaacaact taacagtgaa
     6481 aaattgatag tagaagctta tatagaaaat agttatgaaa aagctttaca agcattcaca
     6541 ttaaataaaa ctattccaag tatgaatgtt gctaaagaaa ttttggatga aatgatagaa
     6601 gttaataagg aatactggcc agaattaaga tagtaggata aaagaaaggg tttttattta
     6661 atcattagat atgttttcag agtcttttat caaaatgtat tcacaaacat atggcaatat
     6721 attaaaataa agagtgatat ttttagaaga atggggtgat gcaatgaaca ttataaataa
     6781 aattttttgg caagaagata ggattggcat gattacaaat aatttagagg cagatacaca
     6841 tagccactgt atgttacaac tgttcttagg gatagaagac agcattgaaa taacagttaa
     6901 tgaaaaatta gttaaatgta attgtatcat agtagataaa aatatctctc attcattttc
     6961 agcaagaaaa aaagtttatt actctgctat tattgaacct acatctatat atgcagaaca
     7021 gcttacctca aaaatgaatg attttggcta ctggatatgt gacaatgatg gattagagaa
     7081 attacgtcaa caaggaactt ttttgatatc taactctagt aaagaacaat atttaagatt
     7141 tatggaaatg cttaataact atttgaatat acctataact ctcaaacatt atgatgacag
     7201 aattactgaa ttgttcaatt tattacatac ttgtaattgt gataatcata ctatttcaag
     7261 ttttgcagat aaagtgtctc tatcagcaag tagattatca catctgttta aagaacaaat
     7321 agggatacct ttaaaaagct atatcttatt tcatcaaatg gagtgtgctt ttagagaatt
     7381 actttctgga aaaaatgtta ccgaagcttc tatgactgct ggattcgata ctccatcaca
     7441 ctttgcaggg acagttaagc gaatgatggg aatgcctgtt tctttatctt tgaaagatag
     7501 cgagtttttg aaagtatatt aaatattctc gttatataat gaagttgtac taagaaaggg
     7561 gctttgttat gaataaagaa tatttagaag aaacaaaaat gttaaattat aatgaaccac
     7621 aacttaagct tttggtatca tcaaagaatt ggttggaatt agatgatttt cataaaataa
     7681 aatctattta tgagtttgta cagaatgata ttttatttgg atataatgct tctgatatgt
     7741 taagcgcaac acaggtatta aatgatggta tgggacaatg caatacaaaa gctactcttt
     7801 taatggcatt attacgtgca gtgaatatcc cttgtaggct tcatgctttt gatgtaacaa
     7861 aagattttca acgaggagct acatccaaat tgatttcact attagcacca aaatatattc
     7921 ttcatacttg ggtagaggta ttttatcaag ataggtggat tgctctggag ggtgtcataa
     7981 ctgataaaaa atatttagaa gcaattcaga agaaattttt taatcatggt ggaacgttta
     8041 aaaagtatgc aatagctaca aatgatttga aaaatacatc tattgattgg gatggtaaag
     8101 atacttttat ccaaaaagaa gctatcgtgt atgattatgg tatttttcca tcaccagacg
     8161 tatttttttc tactcattca caacatatgt caaaattaaa aaatttcata tatgtacatc
     8221 ttatcagaaa aataatgaca aaaaatgtat gtaaggctag aaacaattat attgataaaa
     8281 atgaatgagt gtttaagagg taactatata ggaaatatat agaataatta aaactgtact
     8341 ggttaaaatg aataaaaagg agttatcaca gagcaaactt aaattgttca taggataact
     8401 ccttttctgt attaacttct aataatttga tgtcttttta taaaacatat agatacaatt
     8461 aaaccagtaa atgcaagagt agctgctatt gaaaatgcaa catctattcc atgaatgtta
     8521 gacagcatgt ttgaactcat atgagctttc ttagtagcac ttgtcattat agtaataagt
     8581 atagcagaac ctatagctcc agatatctga cggagtgtgt tattaattgc tgtggcatga
     8641 gatataagtt ctctatctaa tgttttaatt ccccatgtag ttaatggcat taaaaccatt
     8701 gaaataccaa tcatacgaat acaatacatc aatgacacat gaattaaaga tgtatctctg
     8761 cctaaaaaag cgaaggataa agttcctaaa aacaaacatc ctgttcctaa tattgataga
     8821 gcatgaggtc catatttatc taaatgacgt cctgcaattg gattgagtac aaccatcaat
     8881 atagcaccag gtaacattaa tgaacctgaa gataatgcag aaaatcctct tacagattga
     8941 acgtacagag gaatcattaa tgtagcagac atcattgagg catatacaat cataattaat
     9001 attgtagaaa taagaaatgg tttattttta aaaaccctca attctaaaaa aggttcttta
     9061 gattttaatt gacgcaatgt aaataaaatt aatgacataa ttcctattaa tattggtaaa
     9121 tatgtggcaa tattagtcca cccataatta ccttgattag taaatccaat taataaacca
     9181 ccaaaaccta gagatgatag tactattgaa ggtatatcta attttagttt ttgagtttcc
     9241 ccaacatttc ttaataaaat aaatgatagt ataacatcta atatagcaat aggggaaaga
     9301 aacagaaata aactatgcca accaaatgaa tctactaacc atcctgataa agttggacct
     9361 attgctggag caaatcctac tgtaatacca actaaactca tagctgcacc acgtttttcc
     9421 tcagggcata aatagagtat aataacttgt aaaagtggca ttagagaacc agaacccatt
     9481 gcctgcaaca cacgagcaat caacatagtt gaaaaattat tagaaaaaag tgcaataata
     9541 catcctatag aaaagataga cattgatgta ataaataact ttctagtact aaatcgattt
     9601 attaaataag ctgttgtggg tacaataata cctgcaataa gtagataaat tgttgttaac
     9661 cactgaccaa catcagcagt aattttaaaa tctgacatta tattaggtaa tgctgttgac
     9721 aatagtgttt gactgagaga acttataaaa gcaccagtca ttacaattgc tattattaaa
     9781 tttccttttt tattgttact ttgggtttcc ataatttata acgtctcctt ttttaattga
     9841 tttttaatgc tgttcaataa aagtactttt ggtcttaaag tgtcttcttt ttctaaatat
     9901 gcaatcattg catccataat taaagaatca tattgttgat tttttccctc gacgtataat
     9961 ttttttattg cttctagtaa tttaggattt tcaaggagag aagtatcagt tttgattagt
    10021 tcttctatat cttgtatcat tttaaaaaat agcgatttat tatgaaggga aaagtaaact
    10081 tcatcttctt gtttatgtaa aaacattgat ttttcaatta aaggatttag attatccata
    10141 ttttctacaa ctaaatctag aatttgtata gtaaatttgg caataaagta tacatttatt
    10201 tctctttttt gtacatgaat aatgtatata aactgatgaa ttagagcatc caataagaaa
    10261 actaaatcaa atataatttt ttctatttta tcaccatagt tatcaaataa gcttaatttg
    10321 tattcattca ataagttagc tcgtgatttt gtttgcaatt tacttgtagc cttacgttgc
    10381 tcttcagaaa aattttctct tatataggta tttatggtag ttctagaaaa aatatttttc
    10441 catacagcaa ttatctttct gtttaacttt tctgatgctg gaatgtcatt attttcattt
    10501 atggaatgta taatttctaa aaacttttca tcataataat tgattatttc gcagataaaa
    10561 ctttccttag tttcaaaatg cttgtaaaaa gtagctttag acattttaca ctcttttaca
    10621 acatccgata ttgaagtatt ttgaaaaccc ttttggtcaa aaattttttg tgcaatagtt
    10681 ataatgagcc tttgtttttc tgtcacttta ttatctcctt tcacgcaaaa acgtttagta
    10741 ctatagagta cctacaagtt ttaataaata tattatacat catttggaaa aaaaatcaat
    10801 atatagactg taatatgaaa tttttgaaaa atttgttgtt atttttagtc gtataaaaaa
    10861 gaaacttaag agtttcttaa gaattgttta aagaagttgc aataaattag tggtatgatt
    10921 atagtatgaa agagaatgtc ttgaaatttt tctgtatcaa attccaatta tggaggtgta
    10981 gtatatgaaa aagaaaattt gtgtagcaat aatttttgct ctatttatag tttttgtaga
    11041 aatgtttatt gatagctcta gcgaaggaag taaaattatg acagctgaat taagtaaata
    11101 caggaaaggc gtaaatgtat tatcaataaa caatattata gtagcgaata aaaaatatag
    11161 tttgcccaaa gattattctc ctcaggaaag cagtgaagcg agagatgctt tttataaaat
    11221 gaataaagat gctcaaaagt caggattaaa tttaaaagct tttagtacat atagaagtta
    11281 tgaatatcaa gatagattat ttaagtcata tgtaaaagaa catggagaaa aagaagcaaa
    11341 tagattttca gctaaacctg gagagagtga gcatcaaact ggacttgctt ttgatattgg
    11401 aggagatgac cagtcttgtt gggcaaataa aaagttcaac aatacaaaag aagctaagtg
    11461 gttgtatgaa aatgcatata aatatggttt tatacttaga tatccagaag gtaaagagaa
    11521 tataacagga tatatgtatg aatcttggca ctatagatat gttggaactg aacatagcaa
    11581 aaactttgca atgaataatt tgactttaga agaatattta catataaatt aagagatggt
    11641 ttgttaaaat taggttaaaa taaaaaataa cctagactat tagctgtgta aagtgatata
    11701 atgtaaatac aatttagata actactcgaa ggggagtagc ttacacgaaa gtggtaatta
    11761 atcgtcaaga cagtagaaat actcggttaa ttagcaaggg attccttgat agcaagacct
    11821 tcaaaataag cattaggtat gtttgttttg gggtcttttt ttattcaagg aatttttatt
    11881 taaaaaaatt taaatttcaa gtatacataa gagcccccaa acataaaata aatttattga
    11941 agaggagggc aacaaatgtc ttacaaaagt acttatcaag aagtaattaa aaatttagac
    12001 tcaagtttat ctggtttgag taaagaaaga gcagaagagt tgttagaaaa aaatggagct
    12061 aatgaattaa aagaagcaga taaggttcct acttataagc ttttcctaga aagttttaaa
    12121 gacccattag taataattct attgatagct gctttagtac aaatattttt aggtgaaaca
    12181 gtggagtcta taataatttt tgcagttatt attataaact ctgttctggg tgttgtacaa
    12241 acaaaaaaag cagaaagttc attagaaagt ttgaaaaatt tatctgcacc aaacgcaaag
    12301 gtaataagag acaataaaaa aatgacaatt ccagcaaaaa atctagtagt tggagatatt
    12361 gtattcttag aagctggcga ttacatacca gcagatggaa ggcttataga agcacaatct
    12421 ctcaaggttg tagaagggat gttaactgga gaatcagaac cagttttaaa gcatacagaa
    12481 aaaataagtg aagatgtaag tttaggtgac cagaaaaata tggtatttag tggtgctgta
    12541 gttgtttatg gtagaggttc ttttgtagtg actggaacag gtatggatac tgaaatgggt
    12601 aaaatagctg ggcttttaga aagtgctgaa aataaactta caccattgca acaaaaaata
    12661 gaggatttta gtaaaaaact tggtgtaggt attgtaatac ttgctctttt aatatttata
    12721 attcaagtag caagaaatta ctttatggct ggaaatggag aaatgacaca aattatttta
    12781 gattcattca tgttctctgt agcagtagca gtagcagcta taccagaagc tctatcatca
    12841 atagtcacta tagtattggc tgttggaaca aatagtatgg caaaaaaaca agccataata
    12901 agaaaattac cagcagtaga aactttaggt tcaacaagtg taatatgtac tgataaaaca
    12961 ggtactctta cacaaaataa aatgacagta gttgattatt atatgtatgg aactaataat
    13021 gatgagttag ataaagaaaa agtaaactat tcttatcatg ctaaattatt gactatggtt
    13081 tctacattgt gtaatgactc tcatataact agtgatggta aagaagttgg tgacccaaca
    13141 gaagtagctt taataaatta ttcaagtaaa aatgatttag attatgataa attaagaagt
    13201 aagtatatca gaataaatga aataccattt gactcagaca gaaagcttat gtctactgta
    13261 aatagtatat atggagatta tataatgttt acaaaaggtg ctccagatat tgtgtttagt
    13321 agatgtaaat atgctttgaa aaatggttca aaagtagata taacagatga gataatagaa
    13381 gaatataaac ataaaaatga agagttttca aatagagcac ttagagtatt agcttttgca
    13441 ataaaagatg tcccagaaga agattttata ccttcaattg atgacgaaca tgacatgaca
    13501 ttggttggaa taatggcaat gatagaccca ccaagagaag aagtaatgga tgcagtaaaa
    13561 gaggcaaaga gtgctggtat aaaaactgtt atgataactg gtgaccataa aacaacagca
    13621 gcagcaattg caaaagagat tggtataatg gaagaaggag acttggctct tactggaaaa
    13681 gagcttgatg ctttgagtga agaacaacta tatgaaaaac tagaaaatat aagtgtatat
    13741 gccagagtct cgccagaaaa taaaattcgt atagtaaaag catggcaaca taagaataat
    13801 ataacagcaa tgactggtga tggtgttaat gatgcacctg cattaaaaca agcagatata
    13861 ggaatcggta tgggaagtgg tactgatgta gcaaaagatg cttctgctat ggtattggtt
    13921 gatgataact ttgcaagtat agtaaatgct gttgaagttg gtagaacagt atacagtaat
    13981 ataataaaat caattactta tctatttgca ggaaacttag gagctatagt atccatagta
    14041 tttgcagtgt ttgcaggttg gtcaaatcca tttacagctt tacaactttt gtttataaac
    14101 ttagtaaatg actctttacc agcaattgca ttagggtttg aaaagtcaga aaaaaatata
    14161 atgaataaac ctcctagaca cccggatgaa agtatactag caggaggaac attgaaggca
    14221 gttgctataa gaggttgtat aataggtgta gttacaataa ttgcacaata tataggatta
    14281 caagtatctc cagaacttgg agtagcaatg gcattttcaa cattgatatt agctagaata
    14341 atgcaaacat tacctgcacg ttctaataat caaacagtaa taaaattagg ttttttcagc
    14401 aataaatacg ttataggagc agttttagtc tgtcttgggc tttactcttt aacactaata
    14461 ccagtgctaa gaggaatatt ctctatacca acaacgtttg gattgtacca gttggggatt
    14521 tgcctagggt tagcattaat ttcatcaata ttaatggaac ttaacaaatt aataaataga
    14581 agtgaagtaa aataatcaaa aaattaaagg gcatattgat tttaacaata tgccttttat
    14641 aaatagtcta atttattcta tattatcgat tatttggaat gcttttataa cttcaggtaa
    14701 ttctttttct tcaggcattc taaatcttat gaaattttta tcaagtccag taaaatcact
    14761 tccagatata actcttattt ttaatttagc aaactcttgt tgtaaatcta tgtccttgtt
    14821 tttatgttca actgtcataa ttgatacagt atcactagtt tcagctatat taaggttttt
    14881 ccatggaatt aataattgat tttttatatc ttttgttttt tcttttaatt cttctataaa
    14941 ttgaacatca tctaataaat ttgctgcaat actacgagat atttcagaca cttcgtaagg
    15001 agtagaaatc tttttaatag ggctaacaag ttgttctgga agaactgcat atcctgctct
    15061 tagtcctgct aaaccgaatc cttttgaaaa tgtttttaaa gcaattacat tatcataatt
    15121 atttagaagc ttgacagctg aattttcttt tggcatgtat tcaccataag cttcatctac
    15181 cataactgct atatcatatt tagctgcttc ctttactata ttttcaattg atgataaatg
    15241 tataatttgt cctgtaggat tgtttggatt gtctatgtaa attactttat attctggatt
    15301 tattttttca ataaattctt tttcattaaa cttgaaatta tcctctttct ttaaaagaac
    15361 ataatcataa gttgcaccat gcatttttat atctgtctca tattctgaga actgaggtga
    15421 atatcctaaa actttatctc ccttttcaat aaatagtcta tttaaaaggt aaataacatg
    15481 tatagaacca tctgccaaac aaattctgtc agtatctaat gctataaaat ctttccaata
    15541 atcgactata ttatctttta aagcaattga atgaggatat cctcttatca tatcaaattt
    15601 taaagcatta aaagcttcta cagctttgtt tgagtaagac acggtattta taccttcacc
    15661 acagtctatc tcgaatacat cttctgaatg tccagattct attgcataac tttttttcaa
    15721 ctgcatttca atagctttgt taatttttag tttcatactt tatcactcct tatttagtca
    15781 ataataaatg ttataaaagt tgctagattt aaaatattat gaaaatatat aatagtaaaa
    15841 aatgaatata aatattataa tagctcactt tatttaatat gattatatat catatattgt
    15901 aaaatttcta gcattataag actataaatt gaaaatattc agaaaaatac tacaagaaac
    15961 gatttatttt gctcttaaaa taagttaaat gaatgttatt aattttgtaa attgaaatag
    16021 tttaagtata aagttatgat ataatctaat aagggtaatt ctttagatta tattaaggaa
    16081 atataggtat acaataaaaa gttatggagt tggattatgg gatataaatt aattgtaaca
    16141 gatatggatg gaactttatt aggcaataat cataaagtta cagatgaaaa taaaactgca
    16201 ctacaaaaag ttataaaaag cggtattaat gtaactttag caacaggaag agccttcgat
    16261 tcagctaaat gcaatgtaga ttttcttaaa gaggacatgc caataatagc ttgtaatggt
    16321 tcattaataa gagagcaaaa tggaaatata atatattcaa ataagattga tacaagaaca
    16381 tgtttaaaca ttttagatgt attagataaa tacgatattt actaccaatg taatagtata
    16441 gattctatgc tttcgaaaaa aatagaagga cgtgaagata gattaagtgt atttttaggc
    16501 tctgaaacag aagtaattgt aaaagatgat ttgagagaag aaatctttaa aaaagatata
    16561 ctaaaatttg taatcataga agaaaaaaat ccatctattt tagatgaaat aagaaaagaa
    16621 ttgagaaaag ttcaaggaat aaagataact tcttcatggc caaacaatat tgaagtcatg
    16681 aatgaaggtg ttgataaagg taatgcagtt aaaattttag ctgaaaaaat gaatatagac
    16741 agagaagata taattgcatt tggagacaat tacaatgaca tagaaatgat aaagtttgct
    16801 ggtcttgggg tagctatggg aaatgcagaa gaattgatta aacaagaagc tgattatgtt
    16861 acagatacaa atcaagacag tggagttgca aaggcaattt ataaattcct agagttaaaa
    16921 gaatcactta gctcttaaaa cagtatataa taggaaaaaa taggttgact attttgtaga
    16981 tagtaattat aatacaaata gataaaacat aaaaatttag attcagtgaa aaagagagta
    17041 gatatagaga aaatctcagc gaattggggg atggtgtgag cctaatgata acactttata
    17101 ttgaaaagaa ctttggagaa tactacttga aattcagtat ggtagtaggt aatctcgcct
    17161 taagagaata gagtgggtaa acattgttta ccaactagag tggtaacacg gaatatttcg
    17221 tctcttggtc tttttgacca agagattttt tagtttcatt gagttacaag acttataatt
    17281 aaaatacaaa aaattaaaat atgaggtgaa agttatgaaa ttatggggcg gacgctttag
    17341 aaaagcggaa aatcaactta tggaagaatt taataaatct tttggctatg attgtgtact
    17401 gtacaaaaaa gatatcgaag gaagtgtagc acatgttcat atgcaagtaa aatgtggact
    17461 tttaacagaa gaagaaggaa agtctataac agaaggttta aaagggatac ttgaagatgt
    17521 agaaaatgga aagttagtat tggatggaga gtatgaagat atacatagtt ttactgagat
    17581 aaatttaatt caaagaattg gagatgttgg caagaagctt catacagcac gtagtagaaa
    17641 tgaccaagtt gcagttgata tgagattgta tgctaaagaa aaagcaaatg atttggtggg
    17701 tttaatatct gaatttaaag ctactataaa agatgttgct gacaaaaacc cagtgatgat
    17761 gccaggctat actcatcttc aaagagctca agtagtgaca tttaagcatc acttaatggc
    17821 atattatagt atgtttgata gagatgagaa aagaataaaa aatgctatag aaatattaga
    17881 tgaatcacct ttaggctgtg gagctttagc aggaactacg catgatatag atagaagtat
    17941 aacttgtgaa caattaggat ttaaaaaagt agtagataat tttatggatg gagtaagtga
    18001 tagagattat ttactagagc taatgagtga tttttcaatt ataatgatgc acttaagtag
    18061 attaagtgaa gagttgatac tttggagttc tcaagaattt ggatttgttg agatagatga
    18121 tttatataca actggaagta gtataatgcc tcagaagaaa aatccagatg gtgcagagct
    18181 tataagaggt aagactggca gagtatatgg aaacttattt ggtcttttta cagtaatgaa
    18241 aggaatacca ttagcatata ataaagacat gcaagaagat aaagaaggtt ttttcgatag
    18301 tgtacatact cttgaaatgt gtatacaaat aatggataga atgatagcca cactaaaggt
    18361 aaatgaggat aaaatgaaac aagcagtaaa aaatggtttt ttaaatgcaa cagaagttgc
    18421 ggattatttg gttaaaaata atgttgcttt tagagatgca catggtatag taggaagtat
    18481 cgttatatat tgtgaagata ataaaaaagc aatagaagat ttaacattag aagaattaca
    18541 taagttttca gatgctttta aggaagatat ttatgatttt atcgactatg agagtatatt
    18601 aaataaggga ataaaaaaga atttaaaata atgtatttat ttttaaaagc tgtaaatttg
    18661 aatgttatca tttaaattta cagcttttta ttgtgtaaga ttttattata taaaagtaag
    18721 aaacttaaaa gtagtagtat ttaaaataaa tacaaataaa aaattgttat taaaatgata
    18781 attaatatca ataagtattg acaaaattat ttctaaatac tattatatat aatataaata
    18841 ataatgaaaa tcaatatcaa ataaatggga ggaaatctaa tgaacttatt agtgattggt
    18901 ggtcatgaaa gaatggaaaa agattatatg gttatggcca agaaaaaagg ttataagaca
    18961 aaggtatata ctaccatgtc atctaaatta aataattcta taggaagacc agatgcagtt
    19021 gtcatactta catcaactgt ttcacataag atgtctagaa cggttgagtc tcaagctaaa
    19081 aaacaagata tattaatcgt aaggcataaa aatagtagta aggtagcatt taatgaatgt
    19141 ctagatatgg ttgatgaatg tctgggaaat tgttcaaaat gtaagcttaa agacaaacaa
    19201 aaacaaaaaa atatataggt ataaaaaata cataaacata aaattaaaag tactgagata
    19261 atagttataa ttattatctc agtactttta gatttataag gataagtata ttataaattt
    19321 tttattataa tttccaacta cttgttactt tttcatattt tttttacttc tagctttttt
    19381 tctttttttc ttctttatat ttgaagctat tataaataaa actaaaagca ctagaatacc
    19441 tgcaataatc ttaacaaaag tcattaaaat attatttcca gtaaaaaatg gaagactgct
    19501 atcaagatta ttttttgcaa ttaagtctat actgttttct agtttaccat tattatatac
    19561 atttaaagta ccaaccttag cccctttttt tataggcaaa tcaattttat ttaactctgt
    19621 tttggtatca taattgcctt gagattcatc tttttctaag aatatcctat aactattttt
    19681 tggttcataa atcaattcat gttgttttgt aaacaatact tttttagtat ctgtgtattt
    19741 ttctttatca acaatagtag cacacttaaa gttatcaaat ccataatcaa tcagaatacg
    19801 tgagtctaaa tataaatcag cattagttga attaaataca gcaacgataa ctcttctgcc
    19861 atcttttaca gcactcgata aaagacattt accagcagca tcagtatatc cagtttttat
    19921 accatcaact atatcatatt ttatatttat aggttgacct ttgtatgtaa tcttatcatg
    19981 tgatgtcaaa aacttattag tgtttacaaa gtatctctca taaggatatg cttttgtagc
    20041 ttcaaattta agtgacttag tttttacaat ttgtctaaaa gtatcattat tcatagcttc
    20101 tctagctatg agagccatat catgagctgt tgtgtagtga tttgggtctg gtaatccatg
    20161 aggattatta aaatgagtat tagtagctcc aatttttttt gcctcagagt tcataaggtc
    20221 aataaatttt tgtacattgc caccaccaac atatctagct aatacaaaag cagcatcatt
    20281 agcagaatga accaaaagag catctagtaa ctgctttaca gtaaaagatt ccccattttt
    20341 tagatacata ctagagccat ctatttgagg taaatcttta atttctatta cttgatttaa
    20401 atctttaacc tcctttagaa ctaaacaagc tgtccatact ttagttgttg aagctggata
    20461 aagcttagaa tttccatcct tattatatag tattttgcca gactcatagt ccattaaaac
    20521 tgcatgttta gcaactatag ctggttcatt atctgcaaaa gagatattag agcttcctaa
    20581 aaatgaagta aatatcaata aacagattaa taaaagtgat aaatttcttt tcattgtgag
    20641 cctccaaatt ttaaattcat cttttagtat agcatatatt tgtcaataat taaaagaaag
    20701 gagtgattaa tatatgaaaa aaaaagtaaa atttatttcg ttttttgttt tatttatttt
    20761 aataatatca tcaataatcg tttataaatc gcttattttc aaagatgata tttatgttgt
    20821 aagtaaaaaa aatttaccta atgaaaaaac acatgttgta gagaatgaaa ttaaaggtga
    20881 agataataat cacaataaag taactaaaga catagataaa aattttcaaa ataataaaat
    20941 aactatatac ataagtggag cagtaaatag acctggaatt gtaactatag agtcagacaa
    21001 gagactttat gatgctgtag aattactagg aggaacgaca aaagaagcag atttaaatgg
    21061 agtcaatcta tcagtaagat tagaagatga acaacattac ataataccca aaataggtga
    21121 agcaacatct gttacaagta atgatgattc caataaacca aatcagagga atgagtcaag
    21181 aggtgagcct aaaaataaat ccaataaaaa tatatctaac gaatcaaaag taaatataaa
    21241 tgtagcgact atagaagagt tggattctct acctggggtt ggagaagcta cagccaataa
    21301 aattttacaa cacagagaag aaaatggaca gttcagttca attgaggaaa taaaaaatgt
    21361 aaatggtatt ggagataaaa agtatgaaaa tataaaagat ttaatttgtg tagactaaaa
    21421 tataatacaa aacttacata tagatatgtt attataaata tgtatgtata tgtgtgtaca
    21481 tgtggaaatt tagtaaagga ggcactttta tgaaaaaaga acaaaaaaaa cttacagaga
    21541 tgacaacagc aggtggttga gccgctaaaa tagggccaga ggttctggca tcagttttat
    21601 ctcaattgcc taaaaatgat aatatagaaa atttattagt aggactagat acagcagatg
    21661 atgctgcagt ttataaatta aatgatgata tggcacttat ccaaacttta gacttcttta
    21721 caccaatggt agatgaccca tacgtatttg gtcaaattgc tgcatcaaat tcactatcag
    21781 atgtatatgc tatgggaggc aaacctttgg ttgctatgaa tattgtttgt tttccatcat
    21841 gccatgatat ggatgtactt gcagaaatat taaaaggtgg gtttgataaa gtgaaagaaa
    21901 gtggagcact tttggttgga gggcatactg tagatgacaa agagcctaaa tatggtcttt
    21961 cagtttctgg gattgtaagt ccaaataaag ttttatcaaa tgctactgca aaacctggtg
    22021 ataagttaat tataacaaaa ccaattggag tgggtgtatt aaatacagcc atgaaagaag
    22081 gtatggtaga acaacatata gcagataaag taatagaaat aatgatacat ttaaataaat
    22141 atgcagcaat gagttttgag aaatttgatg taaattcggt tacagatata actggttttg
    22201 gtctacttgg tcatacttta gaaatggcca aagcttctga agtaagtatt gaaattgaat
    22261 caaaacatgt accaattatt gaaggtgcaa tagaaatggc acaaatggga attatacctg
    22321 ctggtatgta taaaaatatg cattatgtat ctaaagatgt agaagttgta ggaaatatag
    22381 aagttgcagt tcaagatatt ttatacgacc cacaaacatc aggagggttg ttaatttcag
    22441 taaaagaaga acttgcagag gaacttgtaa aagatatgaa attaaatgga gcaatagaag
    22501 ctaaaattat aggttctgta gttccaaaag gggaaaaata tattacagtt ttataaaata
    22561 ttatagagaa agagtgattg ttttgagcaa aagagaattg tttgcaatgt tgccttcagt
    22621 tgatgaagta ttaagtgata atagaattgt agaaataata aatgaatatc ctagaagttt
    22681 agttttagaa tctgtgagag aagtaataga tttaaaaaga caatttatat taagattaaa
    22741 agaagatgca tcaaactctg taacaataga gtttggtgaa ataatagaat ctgcaataga
    22801 gagagttaag ttaaattact cattatcttt aaaaaaagtt ataaatgcaa ctggtacagt
    22861 tattcataca aatttaggaa ggtctttact tagtgaagat ataaaagatg aattatggtg
    22921 tgctgcttca aggtattcaa acttagaata cgatttggat aatggagaaa gaggttcaag
    22981 atactctcat ttaactagta caataaaaag acttactgga gcagaagatg tactagttgt
    23041 aaataataat gcagcggcag tacttcttgt acttagcaca atggctaaag gaggagaagc
    23101 aattgtatct cgtggagaat tagttgaagt aggtggttca tttaggattc caagtataat
    23161 ggctcttagt ggtgcagaat tagttgaagt tggttcaact aataaaactc atttgaaaga
    23221 ttacaaggag gccattacag aagatacaaa tgtattgatg aaggttcata caagtaatta
    23281 tagaataatg ggattcacag agagtgtttc tatagaagaa ttggttaatt taggtaaaaa
    23341 atataaacta cctgtaatag aagacttagg aagtggagtt tttatagatt tatcaaaata
    23401 tggtttatct tatgaaccaa ctgtattgga ttctattcga caaggtgcag atgtagtaac
    23461 ttttagtgga gataagatgc ttggaggtcc gcaagcaggt attatagttg ggaaaaaaga
    23521 gtatatagaa aaaatgaaga aaaatcaact tactagagca cttagagttg ataagcttac
    23581 aatatgtgct cttgaagcaa cattgagaat gtatttagat gagacaaaag ctatagaaaa
    23641 tatacctact ttaaaaatgt tgacatataa aattgaagaa ttagaagtaa aagcaaataa
    23701 actatttgaa aaaataactg ctttaaactt aaatgcaaac ataaatatag aagatggatt
    23761 ttcacaggtg ggaggagggt ctatgcctct tgaaactata agtacaaagg taatatcaat
    23821 aactcctgaa catatgaatg tttcatcttt agaaaaaaaa ctaagactta gtgaagcaca
    23881 tataatagcc agagtgtatg ataataaata tgtactagat gtaagaacta tatttgatga
    23941 tgaatttgat gtaatagttg aggaattgag aaaagcattt aattaaataa atttgagtta
    24001 ataaatatta aatttagaag tataagtatg aagttttgat taaaaaatag ctacacacac
    24061 ttgtgacttt agtcatagca ggtttagagg gggcaaaaaa tgaaaaatgt agtaattgga
    24121 acagcaggtc atattgacca cggaaaaact actcttataa aagcattgac tggaagagag
    24181 actgatacgt tagatgaaga aaaaaagaga ggtatttcaa taaacttagg atttacttat
    24241 tttgatttac caaacaatag aagagctgga attgttgatg tcccaggaca cgaaaaattt
    24301 ataaaaaaca tgttagctgg agcatcagga attgatatag ttttacttgt tgtagcagca
    24361 gatgaagggg ttatgccaca gacagttgag catttagata ttctaagctt tttaaatatc
    24421 aaaaatggaa tagtggttct aactaagtct gatactgtag atgatgaatt tagagagcta
    24481 gtaaaagaag atatttgtga aaaaataaaa ggaacttttc ttgaagatgc tgaaataatt
    24541 gaagttgatt ctatatctaa aagaggtata gacactctta ttgaaaaaat agataaaatg
    24601 agtgatgata tagaagataa aaatgaaaac tctccagcaa gacttaatat agacagagta
    24661 ttttcaataa aagggtttgg tactgtaata acaggcactt taatagaagg aaagataagt
    24721 atagaagatg atttggttat atatccacag gtattaaaaa caaaaataag aagtatacaa
    24781 gttcatggag aaaataaaga tacagcttat gcaggtcaaa gaacagcaat caatatatca
    24841 aatgtaaaag tggatgatat aaaaagagga gatgttttag ctgcaccaaa ctcattggag
    24901 gaatcaatga tgttagatgt aaaattatca ttggtaaatc atttagataa aggattaaag
    24961 cactgggata gattaagatt gtatcatgga actagagaga tactttgtag agcagttcca
    25021 ctagataaag aattaattga aagtggagaa agtggctatg ttcagttgag acttgaagaa
    25081 agcatagtat ctaagaaagg tgatacgttt gtagtgagac gttattctcc aatggaaact
    25141 ataggtggag gtgtaataat tgacccatct cctaaaaaac ataagaaatt tgatgaaaaa
    25201 gttatagaag cattaaaaat aaaagaaaaa ggcgaactaa aagatataat agaagagtac
    25261 ttaaaaagga atttaaaaaa ttatccaaat ataaaagaaa taatgagcta tagtggtgct
    25321 catgaagaag atgtaaaaag agcgcttgaa acacttatat cagaagataa agtatttatt
    25381 ataggaaata tgtatatgca tataaatcaa tacaataaat taaaagaaaa tacaataaag
    25441 cttttaagtg agtaccataa gaagtatagg cttagaaaag ggatactaaa agaagaagta
    25501 aggtctaaga tagagagtaa ttttaagact agggagatgg atattttatt agaaaaattg
    25561 tctacagaaa atgctataaa aatagaaaat aatatagtat ctctattaga ttttgaggtt
    25621 attttaaatg ataagcaaaa agaaatagca aaaaaaatag aaaaaagatt aaaatcatgt
    25681 ggagtttctt ctatactgac aatagatgaa gtttctgaag gaaatcataa ctatgctgaa
    25741 gtattggagt caatgatagg taataaagta gagaaattag atgatttgta tataatggac
    25801 aaagatattt atgaaaatgc aaagaacatt ttgataaatt atataaaaga aaataaagaa
    25861 ataacattag gagaatacag agatttgatt gattctagca gaaagaattg catgattata
    25921 ttggaaaact tcgatagaaa caaaataact aaaagagtag aaaacaaaag aattttgttt
    25981 tagcagaaaa tgtctgtttt tgctttaagg tataaagaag gaattataat gtcgagtatc
    26041 gtataattaa ttagtataaa atattaatta agaggaagtg taaagtattg aagaatataa
    26101 tacctgatgt aaaaccagat ataaaagaaa gagaagacat gagcctttta tttataataa
    26161 tgggctcagt acttttatta tttattataa aagatataga gaaatatgaa actttattac
    26221 atgccatata tacgatattt ttagtagcta caggagtaat tatatttaat actacaaaat
    26281 ttaaagtaga ttcattttct acatttttag gattaatttt tatagctact ggagtattgg
    26341 agtgtatata tttatttaat tccttgggga ttaaaactaa gtctataatg gagattaaca
    26401 tcacaatatc agcaataaca gatttatttc ctatactggg tgtatactta agttttaaat
    26461 ttgttaagga taacaaacaa atttattcaa gtgtaatttt atttatagca actgctacat
    26521 taacaataac atctttattc ataatatcag gaatttgtga ctatctggga aatggtaaat
    26581 cacaatatgc tttaggagtt ataatatcta tattcataat aattatttct atcattagtg
    26641 gaattgaatt aaattcaagt tcaaataaag gtaaatggga atatgatgaa aaaaagattt
    26701 ttaacagaat aatagtaata ataatcttat caagagttcc aaatctattg catatagtta
    26761 ttgataatag aaatgtagag aggatattat cacaaataat aataaatgta gccttatatt
    26821 atttatataa ttacatagta tctaagaata ttaagaaaac agcactggaa ttgcatgata
    26881 cgaatgaaga attaacaaaa aaaacggaaa gtttaaaaga aaagaataaa aaattaatct
    26941 atgagacaga aaagatagag gaacttaagg gaatacttat gaaaagagaa tctaggctac
    27001 aatctacatt agatgtagca gtaaatagca tagtagtatt tagcaaagat ggagaaatta
    27061 catatgcaaa taagagcttt agaaatactt ttggagacta taaagaacaa gataaattga
    27121 ctgataaaat aaaaaacttc aatgatttga tagaaagcat tcattatgtg tttgttcatg
    27181 agaagaatgc agagaaactt attagtacaa gcgataataa agtttatcaa gctatatttg
    27241 cacctttaat tattgcttca caaacagaag gagtattgtg tgtactagaa gataagacta
    27301 agaaaaagga gtacgaacgc aaacttattg aagcaaataa gagaagtaaa gattttttag
    27361 aaagtattgg agatggcata gtagtgcttg aaggtaataa caaaatatat gttaataatg
    27421 catgtaggga aatttttaaa aataatttag agagtattga tttttcatta gtatgtaaaa
    27481 gtgaagaaag tatagaaaaa agatatgtaa tagatggtga agtaaagtat gtagagatga
    27541 gtttttctca gtatactaat gctggtacta ataaaactat tattgtaata cgtgatacaa
    27601 cctctcgaaa aatatctcaa ataaaacttg aggaaagtca atcatcatat tcaagattta
    27661 tagatatatt acctgatggc atatgcttat taaaagaaga tttaagtata aactatgcaa
    27721 ataagtcgtt tttagatatg ctagctttta caaacataga tgatataaaa gattctaata
    27781 ttaaactatt aatgaatgcg aatactgaag aaaaaatgaa atttacggat aatatggcta
    27841 aagttttaaa tgaaaataga agtatacttt tactggaata tgaattgata aatagttatg
    27901 atgatatagt agaagtagaa ttaagtgcat taccttttgc tatatacaat actagataca
    27961 taatgcttat tataaaagat ttagtacata agaaatattc cgagcaagca gaaaaagaac
    28021 tgcttgaaag atttaaaaca gataaaatca aaacggagtt ttttgcaaat atgtctcatg
    28081 aactaaaaac tccactaaat gttatatcta gttcaaatca actggtagat tctttctata
    28141 gaaatgaaaa gataaaagat tacaataaca atattaaatc tcatgtggat ttagttagac
    28201 aaagttctta taggcttcaa agattaataa ataacattat agatttaaca aagatggagt
    28261 ctgggttcta tacactaaaa cttgcgaaat acaatattgt atctgtaata gaagacttat
    28321 ttatgaatat agaagagtat gcacttagaa aagacataaa aattcttttt gatacagacc
    28381 ttgaagaaat taatgtttat atagacaagg ttgaaattga gagaattatg ttgaatctat
    28441 tgtcaaactg tattaagttt actgataatg gaggctggat atatgtaagt attcattata
    28501 aaatagataa agtaatcata agtgtaaaag acactggagt tggaatacca caagataaat
    28561 tagagttgat ttttgaagaa ttttcacaag ttgataagac tttatccaga aatactgaag
    28621 gaagtggaat agggcttgct atagttaaga atctagtaag tcttcatggt ggagatatag
    28681 aagtagtaag tgaagtgaat aaaggcacag agttcttaat ttcacttcca atgaagggat
    28741 ttagtagtga acattacaca gaagataaga gaatatataa tattcaagaa aaaataaaaa
    28801 tagaattttc tgatatatat tattaaaaat gattatgagc aaaaataaaa taaaaatact
    28861 atttgtttaa atatttaagt tgtaagaaat aggctatcat aaggtaaatt attatgatag
    28921 cctattttta gctaggtttt atatctatat gtgagaacat ataatctcta aattaccttc
    28981 aaaactaaaa tctccaaagt cgtttggtag tataaaatgc ataccctttt ttaaattgta
    29041 ttctacagaa ttgtgtataa gttttccatt tccatccaac acactgtata aagaaaaagg
    29101 tgtattgtgt gtaaaattac attttccaaa aacatctaat ttataaacac taaaaaattc
    29161 gtttgacaca aatgttgtgc atttaaagtc tgatgttgat acgattttat agtcagtatc
    29221 gaaatttata tgaggaacat tcgtaacatc tattgatttt tgaacatgaa gttcacgctt
    29281 attacctgaa ttgtcagttc tatcataatc atagactcta taagtagtat ctgagttttg
    29341 ttgagtttct aaaatcaatg ttcctttgca tatagcatgt atagtgccac ttggaacata
    29401 gaaaaagtct ccctttttta tattaacctt tctaagtagt ttgtcccatt cattattatt
    29461 taccatattt acaaattctt tatgagattt tgcattatga cctattataa tttctgcatc
    29521 atcagaacaa tctattacat accaacactc tgtcttacct aactctccat tttcattttt
    29581 tttagcatat tcatcatttg gatgaacttg aactgataaa ttatcatttg catccaatat
    29641 ttttgtaagt aaaggaaact tatcaccagg tgtgtttcca aataattctc tatttttatt
    29701 ccacaattca gatagttttt tacctttata ttttccattt tctattaagc aatctccatt
    29761 tttatgagag cttatagccc aacattcacc agttgttggc gaatctattt cataattaaa
    29821 tttatcttta agtgcagtac caccccatat tctatccata aaaataggtt ttaaaaataa
    29881 tggttccata atcctgttcc tcctatgata ttaaatttat cctacaaata attatatata
    29941 aatagattat aaaatcaata gtaaaaaagt tttgtccctt gaaatgacat aaagtataag
    30001 gagttattaa ataagataaa ctatgatata taatataaag ttctaaattg gagtgataat
    30061 tatggagttg tttaaggcag aaagcaaaaa atataaaaaa gaatttttaa aattattgga
    30121 gcaatgggtt agtatacctt cattttatga tagaaaaact gtatctaaag acatgccttt
    30181 tggaaaagga gtatatgatg cattaaactg gtttgaaaat ctaggtagag aaaacaattt
    30241 caaagtaaaa aatatagata atcatgctgt tcaaattgaa tatggaaatg gtaaagagta
    30301 tgtagatata tttggacatt gtgatgttgt aaatccaggt gaaggatggg atagtgaacc
    30361 atttaaacta aatattatag gtgataaatt agttgctaga ggtgtatctg ataataaagg
    30421 gcctatgata gtgaattttt tagcactaaa aatgataaag gatttagata ttaatttaaa
    30481 aagaaaggtt agattaatag ctgggggaaa tgaagagagt ggatttaaat gtataaagca
    30541 ttattatagc aaagagccat atggtgtatg tggatttact ccagatgcta aatttcctgt
    30601 attaaatgga gaaaaaggtg gagcaataat aaagttaatt tcaaatatag acgataaatc
    30661 tttatatata agtggtggaa tagagtttaa tacaatacca gataaagttt atataaagaa
    30721 tgtagaaaaa ttgggtaaag ataatatatg ttttgatatt aacaatatat cgataaatta
    30781 tgataatggc aattatattg tgtatggaaa aggtggtcat tcatctaaac ccgaaaaatc
    30841 aataaatcct atattagcta caattaaact tttgtcagaa aatattgatg aaaaatggac
    30901 aaaagattta tataagttga taaatcaaga taatataaat ggaaacttat ttggtttaaa
    30961 tattgagggg aaatgtggaa ttttatcaat ggtgccaaca ataataaata tagtagatgg
    31021 aaaattagaa gtagttttaa gcgttagata tccagaaata ttaaccattg aagatataat
    31081 aaaaaaattt aatttgtata tggagcaaaa taatattaat aaatttgagc ttattgggga
    31141 aaatttaaag caagcaaatt atatagatag aaattcaaaa cttgtaagaa gtttgcatga
    31201 tatatatata aagtattctg gagatttaaa aaatgatgtt agagtaacta gtgcaggaag
    31261 ttatgcttct gaaatgaata attcagtaat atttggttgt gaatttcctg atggtagctt
    31321 tggcaatgtc catagtgcga atgaatttgc tagcttagat agatttataa ctgcaatagg
    31381 tatatatgca gaggcaataa ttacattatg taataaaata taaatacaaa atgtccctta
    31441 tatagacata ttatatatac aattaaaatt ttacttgata tataattgaa atcaaagaga
    31501 aggtgataca atgataacta agaaacatgc aataatagta aagagtttaa gcaataaaga
    31561 tggatatatg acatcaaacg aattagctat caaattggat gtgtctacta aaactattaa
    31621 aagatatata gcagatttaa atagtgtttt aagcaaatat gatttggtaa tagcttcttc
    31681 tagaggtata ggatacaagt taagcggttc taaaaacaat atagccagag ctgttaaaga
    31741 agcaaataaa tatattgatg gttttttaga tgactctgaa gagtcaagaa tgtcaaatat
    31801 aatatgtatg cttattaata gaaattatat gagtatagaa gcaatggcag aagaattaaa
    31861 tctaagtata gccgctataa ataaattgtc tagtaagctt aaaagaaaac ttgaaaagta
    31921 tgacttagtt ataaaatcta aaccttacta tggaagctat atacatggtg aagaaattaa
    31981 tataaggcaa ttaattactg actatgcaat aaaattagat gaaaaaagta aagtgaaggt
    32041 gtttttagat gacattagtg aaaacgatat acactgtata gaaagtattt tagaaaagca
    32101 cttaagagaa aaagatacaa taatttcaga taaagatttt aatcttttgc tttcaaaaat
    32161 aatcgtttct gtatttagga gtaagagagg tcatagtaac aatataaact taatggatac
    32221 aagttataga tttcataact actactttat agaaaatcta atgaaagaaa tatctgataa
    32281 aattggattt aaacttattg aagatgaagt aatttatatt tcaaattatt ctggtgtaat
    32341 agcctataaa ggtacacaag gaagaaaaaa cacaagtgaa attgaggaac gaataagtac
    32401 tgttataagt agtgcacttc aagatatatt ccttatttca ggtagtgatt atacaaaaga
    32461 tgatgagttt atggttgcaa tctctgacca tataaagaga tttttaaata gagctagagc
    32521 taatgtaaaa tcaaataatc ctttacttca tcaaataaaa gagaagtttc ctatagcttt
    32581 taatttagcc gtgtttttat caaataaact agaaactgag tttaatttaa aacttgatga
    32641 agatgagctt ggatatatag ctatccactt tgctgcttca aatgaaagaa tgaaaaaaaa
    32701 tactagtaag aaaatttgta tagtttgtca ttatgggata ggaacaggac aacttatttc
    32761 tgaaaagcta aaacagaata taagtgattt aagtgttgtg ggtgtttatc cagttagata
    32821 tctcgatatg gctataagtc aagatgttga tttgatagta tctacagttg aattaaaagg
    32881 atatgaaaaa cctgtcttat atatagaaaa tatatttgat gatagcttaa ttgaaaacgt
    32941 aaacaaagcc ttttatgaaa aggaagaaag aagaaagata ataagtaaca tgtttgatga
    33001 aaaagctttt ttcagtataa aggctagtac taaagaagag gtcataattt cactttcaaa
    33061 taaactaaaa gaaagagatt ttatagagga aagttctata aaaagtataa tagatagaga
    33121 aaatatttca tcaactgaaa taggaaatct agtagcaata ccccacacaa tagtgaaggg
    33181 agataaaaaa tctataatag gagttggaat acttgaaaat ccaataattt gggataagca
    33241 agaggttcag ctagtattta tggtattttt taatactaaa gaaaaacata atttctcgat
    33301 atttaaatac ctttataatt ttataaaaga tgaaggagga gtaagaggaa ttattaaaat
    33361 atgtgacttt aataaattaa tggcacttat aggtaattaa ggaggaaatt aataatggga
    33421 acaaacatat ttaacaaaga atatgtattt ttaaatgttg atgctaagtc aaaggttgaa
    33481 gttttaaaat ttatatcaaa aaaagctaaa gacttaaact tggcagaaga tgagagctta
    33541 gtatatgaag gtttaatggc tagagaagaa caatttacta caaatttagg agaatctata
    33601 gcaatacctc acactaaaaa tgatgcaatt gaaaatccag cagtagtagt attgaagttt
    33661 aatgaagatg ttgtttggaa tgaaggtgag gataaggtta aattagcaat aagcttactt
    33721 atgccaggaa aaagtaaaga gaatattcat cttaaattat tatcatctct ttcaagaaaa
    33781 ttaataaata aagaatttaa agattctctt ttaaaaagtg ataatgttga agaaatatct
    33841 aacttaataa atgaagcttt aggtttataa ttaaacacta aggttataaa ataaaaaaat
    33901 aattaactaa aaataggagg aatttgaaat gaataaaaaa ttagtagcat tatgtgcttg
    33961 tccaatggga ctagctcaca ctttcatggc agcagaagca atagagcaag cagcaaaggc
    34021 attaggttat gaagcaaaag ttgaaactca aggtgctgat ggtgtacaaa atgagttaac
    34081 aagagatgat atattaggag caactatgat aatacatgca gtagcaataa caccagaagg
    34141 tatggaaaga tttgatggtt gtgaagttta tgaagttgaa ttacaagaag ctataaaaaa
    34201 tgcagaaggt gttataaaag aaatagaaga agatttagga atataataaa tttattgtgg
    34261 aggaaataga atggcaatta agaaaaaagt tataaacagt tcaggtgctt ctacaacagg
    34321 aggaaataat gtaggaaaat ctactccatc tagtccaact caatcaaagg gaaatggaaa
    34381 atggaaagaa ataagtaaac atataatgac aggtatatca tatatgatac cagttttagt
    34441 aatgggtgga cttatagggg ccttatctca attaatacca tatgctatat taggacttga
    34501 cccatctgta ggtatagttg atgctatgaa ctcaggagaa tttacagggt tcaagcttag
    34561 tcttttaaat atagcacaat taatgtcaaa tttcggattt actttgtttg gatttgcgat
    34621 accactgttt gcagcatttt gtgcaaactc tataggtgga aaaacagctt taattgcagg
    34681 atttataggt ggatatatag ctaataaacc tgtaggtgta ccacaattcg ttgatggaca
    34741 atggactgaa gttgttccag ttgcatcagg atttttaggt gcaatactaa tagcatttat
    34801 aataggatat tttgtaaaat ggttaaataa atctataaaa gtttctcata actggttagc
    34861 ttttaaaaca acatttttaa taccattaat agcgtcatta gcttgtatgg tattgatgat
    34921 atttataata actccatttg gtggattaat taatgaaagt atgaaaaact tcttaacagc
    34981 agcaggagca gctggagaat atgtatatgc aacagctttg gcagcagcta cagcattcga
    35041 cttaggagga ccaataaata aagcagcagg attcgttgca cttggtttaa ctacagagaa
    35101 tgtacttcca ataacagcaa gaacaatagc tatagttgtt cctccaattg gattaggatt
    35161 aacaacatta ttagataaaa gattagtagg aagaagagta tatgatagac aattctatca
    35221 agcaggaaaa acttctatat tcttatcatt tatgggtata tctgaaggag caataccatt
    35281 tgcacttgag agaccaggtt ttgttatacc tttaaacata gttggaagtg taataggagc
    35341 tattacaggt ataattctag gagcaattca atggttccca gagtcagcta tatgggcatg
    35401 gcctctagta gataacttat ttggatatat aataggtata gcagttggtg ctatattcat
    35461 agcagtagga aatatattct atagaaataa attaataaaa gatggtaaac ttgttgtaga
    35521 ttatatcgac tagtatttaa tttttactat ctataaataa ctttggctgg taatatggtt
    35581 ttaatcaata ttaccagcct tacctatatg attaattaaa ggcggtggag ataagatatg
    35641 gataagatag aaaaagtaag agagtatttt agagaatatg atatagatgg atttcttata
    35701 aatagtccta caaacaagtt ttatgttgga aatttattta gctcttcagg ttatgttttt
    35761 ataactaaag aatcacaata tataatagta gattttagat attttgaaga aattaaaaga
    35821 aaatctagtt tgtttaatgt agtattaatg gacaaaacta gaactcattt tgatataatt
    35881 aatgatattt gtagagagca gaatataaag gaaattggat ttgagggaaa tgaagtatct
    35941 tttgatttat atagaagtat gagtaataag ttaagtgcaa ccttaaaatc agttgattta
    36001 tctacattaa gggaaacaaa aaatgaagac gaaataaaat atataaaaaa agcttgtgaa
    36061 atagttgatg ctacatttta tcatatagta gactttataa aggttggtat gactgaaaag
    36121 caagttgaaa atgaaattgt tagaattata aaagatttag gtggtcaaaa agaatctttc
    36181 gatacaatag ttgcatctgg gcttagagga gcattacctc atggaaaagc aagtgaaaaa
    36241 gttatagagt atggagattt tgttaccttt gactttggtg ctaagtataa taattattgt
    36301 tcagatatta ccagaaccat ttgtatgggt actataaata aagagttaga agaaatatat
    36361 aatatagtaa gaaaagctaa tgaagagtgt ataagggttt taagaccggg aatgactact
    36421 ggagagatag ataaagttgc aagagacata attggttcat atggatatgc caataatttt
    36481 ggtcataatc tgggtcatgg tgtaggaatt atggttcatg aatatcctgc attagctcct
    36541 gaatcaaatg aagtattaaa agaaggaatg attgtaacta tagagcctgg tatatatgtt
    36601 ccaagtcttg gaggcgtaag aatagaagat gatgtactta taacacaaga tggatgtatg
    36661 agattgacta catctactaa ggatttaata gttgtaagct aaaaataaat tagataaata
    36721 ttttataaca ataagaaaag aagaggtaaa tttaaatgta taattttgat gataaaccag
    36781 atagagtaag tgaaaagtgt agaaaatggg atttaaatat tataagagat aaatttggag
    36841 atattagaga agattttata ccaatgtgga ttgctgatat ggattttaaa ataccaacag
    36901 aaatagaaaa caaatttatt gaagctgtaa gaagaggtgt atttggatat acatactgtt
    36961 atgatgaatt ttatgattca gttattggtt ggcaaaaaaa tatgcatgag gtaaatgtag
    37021 aaaaagaatg gattacatta acttatggaa ctgtatcaac acttcattat gtagtacaag
    37081 ctttttgtaa gaaaggtgat agtataatat taaatacacc agtttatgac ccctttgaat
    37141 catcagcaaa aaaacaaggt gtaaatgtaa tttgtaatac attagatgtt gtaaatgata
    37201 gatattatat aaattttgat aaattagaag ttcaaattaa agaaaataag cctaaattaa
    37261 tgatgttttg tacaccacat aatccatctg gaaggatatg gacaattgaa gaaatgacaa
    37321 gggtagcaac tatatgtaaa gaaaataatg ttattttggt tgcagatgaa gtacatgcag
    37381 agcatattca ttatggtaca tttaattcaa tacttaagat tggaaaagag cttttagaaa
    37441 atgttattct attgacatca ccaaataaag gatttaatct tggtggatta aagacttctt
    37501 attcaatagt tataaataag gatataaggg acaaatttag aaataaatta aagcaaaatt
    37561 ctataacttc tccaaatgtg tttggaataa taggattgat aaccgcttat aatgaatgtc
    37621 atgagtggtt aagtggtgta aatgaatata taaaatcaaa ttatgaactt ttagaaactt
    37681 gggtaaataa atataataag ataaaattga tgaaaatgga atcatcttac ttagcttgga
    37741 tggatataag tggattaggt attagtgcaa gtgagtttac agataaattg gctatagata
    37801 caggagtatt attagaagat ggaagtcatt ttgtaaaaga tggtgagaag tatgttagaa
    37861 taaatttagg aactcaaaag gaaaatgtaa ttgaagcctt aaatagaatg gatttatttt
    37921 taaagtcttt ataaaaattt ggttgaatta gtattttata taaatttaaa ctattaatat
    37981 ggtatataca taagtagaat ttgttttaga ttacttaagt atataccata ttttatataa
    38041 aaattaaatt tgcattagtc atgtgataac tatttaaatt catatgtatt ttgtatgtat
    38101 aatagatata attattattt aaacttattg tttatttaat ttttcaatag aaaaagattt
    38161 atctgtaagt ttaaaattat cttttatacc cttagttaag tatactttct tatccttagt
    38221 tatgaatata gcatctacat tatcaatttt attaattaaa ttcatacctt tttcaagacc
    38281 aagaccaaat gtagaagtgg ataaggcatc acaattaata gatttatcag agattattgt
    38341 aacactactt aaattgtttt caaaaggata ccctgtaaat ggatttaaca tatgatgata
    38401 tatttttccg tctttttcga taaatctttc ataaattcca gaagtaacaa cagacttatt
    38461 tgtagtttct atgtttccta tggattcacc atttttacta gttgggtctt gaatacctat
    38521 tttaaaaggt ttatcatttt taccattttc taaagtaaat atatttcctc ctaagtttac
    38581 taaacctttt tttacatcct ctgattttaa ataggctaca attttatcag cagcatatcc
    38641 tttagctatg gcacctaaat caattttcat attttctttg gttaatttta tagatttatt
    38701 tttttcatcc aatatgatgt tcttataatc aataagaggc agaagttttt gtatcttaga
    38761 atcacttgga actttagctt tatctgttcc aatagcccat aaatttgata atggaccaat
    38821 tgttatgtca aaatatccat ctgataattt ggaatattgt atagcttctt ttacgacgaa
    38881 aaatgtatca tcagaaactc tgacaaattt tttaccagca ttatcattta ttttagaaac
    38941 atcacttcct ggtatatgag tgctcatttt gttgtcaata tatcttaaaa ttgaatcaca
    39001 ttcatttaag attttatcac ttttggattc ttttacatta aatacagtaa cttcgtttac
    39061 tgtaccaagg tagtagctag ttttactata tttagtattc tggcttgaac tcctaaaaaa
    39121 tgaaaataaa attaatgcta aaatcaatat cacaaaaata aatgtgattt ttttcttatt
    39181 catggtatat tcctcctatg aaattgtgtt attattttat tataacataa tttcatagga
    39241 ggacaaaaaa tgaagaaaaa agacattctt cttattttag gcattttggt tgttattaca
    39301 gcatgttatg ggataataaa tgttataaat tctaaaaatg ctggaaatat tgagatttat
    39361 gtagataata aattgtataa aactgtttca ataaatgcca aagaagaatt taaaatagag
    39421 agtagagggg ggtataacat agtaaagatt catgataaag gggttgagat agtagatgct
    39481 tcatgccctg ataaggtttg cgtacatact ggatttataa acaagccaag tcaaagcata
    39541 gtttgtatac ctaatagagt gagcataaaa ataaatacaa atgaaaagaa tgataatcaa
    39601 gaagatataa tttctaaata aaataataaa aataattgaa aggaattggt gataattatg
    39661 gttaacttag gaaacgattg ggatgaatta ttgaaagaag aatttgaaaa agattactac
    39721 ttaaacttaa gaaaatttct tatagaagaa tataaaacac gccaaatttt cccaaatatg
    39781 cacaatatat atgaagcttt aaaacacact tcatacaaag acacaaaagt cttaatatta
    39841 ggacaagacc cttatcatgg agataatcaa gctcatggtt tagctttttc agttcaacca
    39901 caagtgaaaa ctccaccatc tttattaaat atgtataaag aattaaaaga tgatttaggt
    39961 tgttttatac ctaataatgg atatttaatg ccttgggcag accaaggagt gttactttta
    40021 aatactgctc ttactgttag agcgcatgaa gctaattctc ataagaacaa aggatgggaa
    40081 attttcactg atagagtaat atctatttta agtgagcgtg aagacccagt tatttttgta
    40141 ctatggggaa gtaatgcacg taaaaaagta gagttgattg atacaagtaa acattatatt
    40201 ttggaagcac ctcatccaag cccattgtca gcaagtaaag gcttttttgg atgtaaacac
    40261 ttctctaaga taaatgaaat tttgaaaaag ctaggaaaag aacctattaa ttggcagata
    40321 gaaaatatat aaaagtaaaa ggtaacaaaa tgataacaaa acaacaataa acaatgacat
    40381 tgttgtaact aatagaaata tgcttaaata gttgaaaata ctatgtatgc atatttctat
    40441 ttttttgtca agttgacaac tcttgaaaaa atagttacaa tttagttaca caaaaaacac
    40501 aaataaaaaa agaaacttac aaagcagaat tttatgaagc aaaatatata gtgtaaaaaa
    40561 tcttagggag gaaattttat atgaatttta aaaaattgag taatgctaaa gtctcggtaa
    40621 tggcagttgt tttatcagtt ggaatattat cgggatactc tgcgcttaat aaacaagtaa
    40681 cattagtagt aaggggagaa gaaagaacta tatcaacatt tagttctaat gtaggagacc
    40741 ttttagaatc tcaaaacatt agctatgatt caaatgatat agtaacttta gatgaaaata
    40801 caaagttatc taatggagat aaaatagaag taattgatgt aaaggaaaaa acagttgtag
    40861 aaactaaaga cattccattt gaagttacag ttgttgaaga tggctcttta ttaaagggtg
    40921 attctaaggt taaagaagaa ggaaagtctg gtaaaagtga attaatatat aaagaaactt
    40981 atcacaatgg aaagaaagta gaaaaggaat ttgtgaaaaa ggttgttaaa gctgagccag
    41041 taaataaggt tgtaagcaaa gggacaaagg tagaaatgca agtagcctca tcaaggggag
    41101 aaagttcaag aagaatggct tcatcatcat ctagtagcag tagtagtaac aatggtaaaa
    41161 atatgagagt ggtagcaact gcatatactg gtcacagtat aactgcaaca ggaacaaaac
    41221 ctaagtgggg aacaatagct gtagacccta aggttatacc atatggaact aaagtttata
    41281 tacctcaatt tgacatggtg tttactgcag aagactgtgg tggagcaata aaaggaaata
    41341 aaattgatat ctacatgaat gattcaaaaa cagtttataa ctggggaaga aaaactatag
    41401 atatacgtat attaaaatag ttaaataatt tatattttta ctggaaatta tattttgatt
    41461 atatagagaa gaaactcttt atagattcta aaaatataat ttccagtttt ttattttgga
    41521 tatgtaataa aacaggtaaa ttttaaccat gtatagataa aagctattta aattataatt
    41581 tactatcata taaatctata aaaattgttg caaagagtca aaatatatga tattatagat
    41641 ttcgttgaga aggatttcat tatgggagtg gatgggtgcc ggtgtgccct ctagtcttca
    41701 aaactagtat gaggggttaa gagcctctta ggtgggttcg attcccacgc attcccgcca
    41761 atatgtaaaa ggtatctttt aattaaaaga taccttttta aatttatttt aagataattt
    41821 atttttaata atatataatg ttttgtatta tataatgtaa attttctaat acaaaacatt
    41881 atatatttag ataaaaatct aggagtgtgg aaagatggaa aataatttta caacgagaac
    41941 tagttttcta gttggagatg atgggataaa aaaacttaat aattcaaata taatagtatt
    42001 tggagttgga ggagttggta gttttactgt tgaagcttta gcaagagctg gagtaggcaa
    42061 tattactatt gtagattttg atgatgtaga tataaccaat ataaatagac aaataccagc
    42121 cctacattca actgtaggaa gatacaaagt tgatgtcatg gaagaaagaa tattagatat
    42181 aaatcctaat atcaatataa aaaaaataag aagtctttat aataaagata ctagtgacga
    42241 aatactaact gaaagatatg attatgttgt ggatgcgata gacatggtaa gttccaaaat
    42301 acatctaatt gaaacttgtg aaaaaaaagg attgaaaata ataagttcta tgggtatggg
    42361 aaataaatta gacccaacta aaatagtcgt tacagatata cacaaaacaa gtacttgtcc
    42421 tctagctaaa gttatgagga aagaacttag ggatagaggt atcaaaaagt taaaagtagt
    42481 atattctact gaacaaccaa tagaacttaa gaagaaagta atgaatggta gaaaagtaac
    42541 acctggtagt gtatcatttg tcccatctgt aggaggttta ataatcgcat ctgtaatagt
    42601 aaatgaacta ttaggacaat aagttttaaa tattttaatt tataaatttt atatacaaat
    42661 ttgaaggcta gaagcatgaa tacaaagcaa ttttatattc atacttttag cctaattatt
    42721 ttatattacc ttattttatg tagttgtagt tttatttttt agattatgta tctatttcat
    42781 aattatattt tgtaaatata atttctccat cactataaaa aacaatatct cctattctat
    42841 ctgttctata aattgataca tggttttgtt ttagattatt aataacctcc ctatgtggat
    42901 gaccatattg atttttatat ccacatgata ttgcagctat atctggacta atttttttta
    42961 taaattctaa agatgaagaa gaattacttc catgatgacc tatttttata aaattaatat
    43021 tatttaattt aaaagaatgt aaaatttctt tttcattttc ttcttcagca tcacccataa
    43081 ataaaaaaga attatcatta aaagttaatt tgaaaactat agaatttaaa ttagattctt
    43141 cttgtatata tgatggactt aatacatata tatttatatt gttatctatg tttaaaacat
    43201 catttttata gagatgctga atagataagt ttttatccgt acaagaattt attagatttt
    43261 gataagcctt actatcagtt gattgttcag gcatatatat ggagtttaca ttaaattttt
    43321 ttataatatt atcaagactt cctatgtggt ctgaatctgg atgagttgct attataatat
    43381 caatagtttt tattcttttt tgtctaagat aactaataat tatattttcg ctatcttcat
    43441 cacctccatc aattaatata ttcttatttg tgggtgtttg aactaaaata ctatcacctt
    43501 gtccaacatc aatcatatgt atagatagta gagatttttt gtcacagccg attaaaagtg
    43561 atattataat aagtattgat aaaaaaattt tatttctcaa taaaaaatca ctccattcat
    43621 tacatgttta tataaattta tgatgggtaa tataagatat atatgactta ttatatttta
    43681 tattttaaac aatataaatg aaattaatac cataataaaa ttggagtttt ttatatatac
    43741 aaaataaaat ttttaaaatt aagcaataaa aaaggtagga ggattttatg tttttcaaag
    43801 atattgaact aaattcaaaa aaagagttag acccatattt tgatttagta gattatgaag
    43861 cttgtgagta ctgttttagt actttatata tgtggcaaca tgtttataag acaggatatt
    43921 atataggtga agattttgcc gttttagttg gggaatacga aggagatagc ttctcaatat
    43981 taccacttgc taaaaaagat aaacttccag aagttgtaga ttttgtcctt gaatattttt
    44041 ctaaaaataa taaaaaaata tacttaagag gtattactac tgaagtagta gagtttttaa
    44101 aagaaaaata tccaggtaga tttgagtata tagaagaaag agatttattt gactatattt
    44161 atgatgcaga aagtttaaga actctagctg gtaaaaagaa tcaaaagaag agaaaccata
    44221 taaactattt cttaaaagag tatgcaggta gatatgaagc taaattatta gataaagaaa
    44281 actttgatga gtgtttagta ctaatgaagg aatgggaaag taataaggaa gaaaataatg
    44341 aatttgatga aagtatggat gatgaattaa taggtatcaa aaagatattt aaccattatg
    44401 acatattaaa agataaggta aaagtgtttg gtgtttatgt agatggaaaa ttagaagctt
    44461 ttagtatagg agagctttta aatccaaata tggcattgat tcatatagaa aaagctaatc
    44521 ccgatataag aggtctgtat ccatttataa atcaacaatt tttggtaagt gaatttaagg
    44581 acgttgagtt tgtaaataga gaagaagatt taggtattga aggattaaga aaagctaaac
    44641 tttcttatca tccttgcaga tttgttgaaa agtacagtgt tagggaggct taatagacta
    44701 tatggagatt aggtatgcta aagaagaaga gatagaaagt ataaaagata tttggagtta
    44761 ttgttttaac gatacggaga gttttatgaa gtactatttt aatgataaat ataaatctga
    44821 aaatactgta gtagctttag atgaaggaaa aattatttct tctcttcagc taaatcagta
    44881 taagttatta ctaaatagca aggtatataa tacatcatat gtggtaggag tttctacact
    44941 tccagaggga agaggagctg gatatatgaa caaagtaatg aaatttactt taaacgaatt
    45001 gtataaaaaa gggcaattag tttctatatt gatgcctatt gactatagac tttatagaag
    45061 atttggatat gagcattgtt acgaccagat tgaatatact attaacacag atgatttaaa
    45121 aaattttaag tcaagtggaa aaatgataaa gtctaattta tcacaaattg atgatttgat
    45181 acaaatagat agaacttttt taaatgaggt taatggtaat gtgttaaaag atgaacatta
    45241 ttatgaaaac ttatttaaag agattcaaag tgaagatgga tttttataca ttcatgaagg
    45301 aaatgaaaaa gatggatata tagtttattt tcttcaggaa gataaaatgt ttgtcagaga
    45361 gttattttat aaaaatatag atgcccttaa atcaatgctt aaatttatat ataatcacaa
    45421 tactcaatgt aagatagtta ctatatctac tcctacaata gataagataa ggtttatatt
    45481 agacaaccct aaagatagtg atataaaaat aaaacctttt atgatgggaa gagttataaa
    45541 tgtaaagaag tttattgaag atatagatat tgagaaggat attaatagct catttaattt
    45601 attaatagaa gacaagttta tagatgaaaa taatggtcta tttaaaattt ctatacagaa
    45661 taagaaggta tctgtagagc agttagataa aaaaggtgca gaaaagcctc aagaagattt
    45721 tgatattaaa ttagatataa ataccttaac acagttatca ttttcttata tagatgtaaa
    45781 tgaagctatt ttcttaaatg atataaaaga tgtttcagaa gaaacactag aaacacttaa
    45841 ttgtattttt tctaaaaaaa ataactatat aaatgaatat atataggtag agtacgttaa
    45901 aagattctaa aaatcttttg acgtattttt ttgtttagat aacaatttat cttgtttaaa
    45961 aattttctat ttgaaaataa tctaaataat atacttttat atgggagtga ttataattca
    46021 aataagaaga ccattattaa ttatattaat gtttgtggta gctatatcat ttatcattac
    46081 aaataacaca aaaaacgacg aagaacttaa tgataagata ataactatac aaggagttgt
    46141 caaaggaaaa attgaaaaga aaagatacaa tcagtacaag gtaggggttt ttctaataaa
    46201 tgattataca aaaaataaaa atttgaagat tggtcagaaa gttaatatta caggtaaatt
    46261 caaaagttta gataaaatga agtatgatga ttttgattat ggaaggtata taaaaagtac
    46321 tggatataaa ggtatagtgt atataaataa ctataaaatt attgataaaa ataaacttta
    46381 ctctttaata ggggaaataa agttttatat tagtaaaact tataggtact tatataagaa
    46441 aaactcagat tttataaatt ctatactatt agcagaagtt gaaaatttga ctgaggaaca
    46501 aaaagaaatt tttaccagaa ctggaactag tcatgtaata tctatatcag gtcttcatac
    46561 aggaatatta tgtgtaatta tatcctttct attaagaggt ataaataaat tgtataaatt
    46621 attaatactg tcgattttta taactttata ttgtataatg gtaggtgcgt ctccatccat
    46681 aattaggtct atagcatttg ttatgatttt ttatttatca atatttattg atagaaagaa
    46741 agatggaata tcggcattgt ctctaattgg gataatttta attatgaata acccctatgt
    46801 tatatataat gtaagttttc aattgtcttt tttagctaca ctttctatat taatattcta
    46861 taataaaata aatagtatta taaaattaag tatggtatca ttgacaatat catcaaatat
    46921 attaacttta cctataattt attatacatt taaaggtata ccattgcttt caattatagg
    46981 aaatttaatt atagtgccat ttgtgggagt aataatgtat ttaagtattg caagtttaat
    47041 cgtatttaaa gtaagtgtag taatagctaa aattatatct ttttttaata gtacatttat
    47101 agaaagcata ttttttttac tagaaaaaat cagcaattta agttttgcat acattaatat
    47161 agaaaatcct aaattttata ttgttgttat ttattacata ggagtgtttt tttacatatt
    47221 ttacatagaa ggaaaagaga taaaggagca agagaatgaa ttacaaggat attataagga
    47281 atgtaaaaga gaaaaacttt gaaaaaatgt atctttttta tggaagagag tattatttaa
    47341 ttgagaatgc aataaaagca tttaaagata gtctaaacga gggaatgctt gattttaatt
    47401 tagatataat agatgggaag gaaatagtct taaatcagct tataagctct atagaaacac
    47461 ttccatttat ggatgatagg aagatagtaa taataaaaga ctttgaacta ttaaaaggaa
    47521 agaaaaagaa ttttacagat agtgatgaga aatacttaat agagcattta gacaatattc
    47581 cagacaccac aactatagtt tttgttgtat atggagatgt agacaaaaga aaatcattag
    47641 ttaagaaaat aggaaacaat ggaattgttt ttgattgtga taagctttct gatatggatt
    47701 tgtttaaatg gataaaaaaa tcttttgctt taaatgatgt tataatagat aattctcaaa
    47761 tcatgtattt tattgaacaa gaaggataca gagataagag tagtgaaaag acattatctg
    47821 atttagaaaa tgaaataaat aaaataagtt catttgttgg taaagggaat aatgtaacca
    47881 atgatgtaat tgataaatta tctcaaaaaa aagttgagaa tgatatattc aaattaatcg
    47941 attatattgg agaacaaaat gcttctaatg caatgaaaat attaaatgat atgatacaag
    48001 aaggcgaatc tgtattaggt atattttcta tgatagcaag acaatttaaa ataattatgc
    48061 aagtaagaca gttacaactt gatggatatt caacaaaact tatagctgat aaattaaaaa
    48121 tgcatcaatt tgttgtagga aaagcattaa agcaaactaa aaatttttct gatgatataa
    48181 ttgtggaaat attaaactat atattagaaa gtgattacaa aataaagaca ggtcttataa
    48241 gagatacttt agcagttgaa atgttggtta gtagatactg taaaagagaa gcaatttaaa
    48301 aaatctatat attaataaaa aataaatagc aagatatgtt atagttcaga gtagatgtaa
    48361 gctaaattaa gtttgatata caatcaacta taatatgtct aactatttat tttttattgt
    48421 ataaatttac aaaataaaaa acccctacat aggggttatt atatataaga aatataaact
    48481 ggtaattaag cgttcatacc gtttaatttt tgagctaatt tagctacttt tctagctgca
    48541 gcattcttat gtatagttcc tttagaagct acttggtata ttcttttttg agcgtattgg
    48601 aacttagcaa cagcatcctc tctgtttcca gctgcaacag catcttcgaa tcttcttatt
    48661 gcagttttta tttgagattt tctaactcta tttaaagcag ttttcttttc gataacactt
    48721 attcttttct tagctgattt tatatttgcc accgtgttca cctccctgta tttttttatc
    48781 atattcatcg tcaacatatt agattttaac agaaataaat ctaaaaatca aggattatta
    48841 tttatatatt ttaataatgt tttttatttt gattttttag actgtaaatt gtgtataaat
    48901 aatttgcaat atcttgtttt taaattggta tattttgtgt tttaaatatt ttgacatata
    48961 taattaatat ttcattttgt aacaaatatt tgagataata caaactatta acatacattt
    49021 tgatagtatt tccaataatt ataagataat acaagaaatt actcattttt gtaaatttaa
    49081 tgaaaaatta taaaaatata aatttatatg cttaattaag ataatttttc caataatcaa
    49141 gataattttt ttcattagta tgtatgatag atgcatcaaa caatataact aatatgttag
    49201 aaggttatat gtaattaatg tcagtgttta tatagaatag catttgtagc atttattata
    49261 gttgtaatta ctatttatat catagacttg aatagtctaa aaaaatagac tataatattt
    49321 ttatagacta aagaaagggc tgataagatg gacatagcaa aactaatttt aaatcctgca
    49381 aggcttcgta ttttacaata tattcgactt tatggcagtg ttcgtacatc tgatattgta
    49441 aagtatttaa atgatattcc tcgtgcaaca gtttatcacc atgtaaaaat tttagaagag
    49501 aacaatatga ttgaagtaat taaagaaaat cgtgtgcgtg gtactattga aaaggtttat
    49561 gcactaaagg aatatacaac atctatggaa ggagagacct tcgttgcact ttctacagca
    49621 ttttatgtag gtctgatgca ggaaatgaat gaatacttta gcagaaaaga gcaagaccat
    49681 aaaaaggata atgtattttt ctcttcagca ttactatata tgagtgataa tgaatatgaa
    49741 aatcttctta aaagtatagc tgatttattg aaaccatata tagaacaaaa acctaaatca
    49801 aatctaaaac ttagaaaact ttcaattata tcttctccac ctgtagctga taatgataaa
    49861 acaaaataac atgcaaccca tttttataaa aggaggttat atatgaaatt tcatgagttt
    49921 ggaaataaaa acagaccaca tattatgttg attcatgggg gagggaatgc atggtggaac
    49981 tatttgcgac aagcagaagt tttgtctaac aaatatcatg tgatacttcc tacattggat
    50041 ggtcatggag aagaatatga aacaacatac atttctacag aggatacagc agataagttg
    50101 atatcatata tagatgaaaa ttgcagtgga catcttttcg ctttgtgtgg ggtatcactt
    50161 ggtggtcaaa ttgtcatgga acttttatct cgaaaaccta atattactaa aaaagcaatt
    50221 attgatggta gtatttgcta cccaagacct cttatggcaa ggttttgtat tgctggtatt
    50281 cgattttttg gaggactttt gtttagtgag aaggcttgtc gctttcaaat tgctatgatg
    50341 ccaaaattgt tacctgaaaa tatgcaatat ccagatgaaa taaaagcgta ttatatgaca
    50401 gatatgccac atgtaagaaa agaaacattc tataatatgt atcgtactta catgatgaac
    50461 tatacactta aagagaatgt taaaaaaacc acagcacaag taatgtactg gtatggagaa
    50521 aaagaaatga agtgtgtcaa aaaatctgca aaactgtttc agtcttatgt gccctcttgt
    50581 gagatttatg aagctaagag ctataatcat gggtatttat cactttatct tccaaatgaa
    50641 tggttggaaa ttgcagaacc atttttccaa aaggaataaa ggtgttaggt gattattgta
    50701 taattattgc tgttttttta tatagtaaat aaattaggta taaatataaa aaattatttt
    50761 agttaatata ttagtgaaag cttaatagga aaattataaa tagattaaag gtagcaccta
    50821 tataaatagt tgctaccttt ttctgtttgt aaataaatga tagataagaa ggtttactga
    50881 caaatcactg actaaaccca attttcttac attgaaagcc ttaattttac ttgttttaaa
    50941 taaatttaca atttcttgtt ataaaatact aaattttgtt aacaattata attagcattt
    51001 aatttatact ggaggtttat atgattagtg taagaacaga tttagcttta gaagctagtg
    51061 aaatgtgtga aaagtctcaa gaaggaagta gtattcctgg tgtaaaaata gaaactaaag
    51121 aattagaaaa ttgcattgta actaaagttg aagtaataga caggcaaggc gcagagataa
    51181 tgaataaaga tataggaaag tatataactc tggaaagtaa tcttatgaag tttgatgatg
    51241 atgagtcaag agaagaaatg ataagttatt taaaagagga gttagtagat atatttggcc
    51301 aagacaaaaa taaaaaaacc ctggtaattg gtcttggaaa tagaaatatt acttctgatg
    51361 cgttaggacc aaagagtgta tcaaaaacac ttgtaactag acatcttttt aaaaattata
    51421 ataaagacta tgatgatgat ttcactgagg tatcagcttt aagcccagga gttatgggtg
    51481 ttactggaat agaaactagt gaaatagtaa aatcattggt tgagaaggtt aagccagata
    51541 gagtagtagc aatagatgca ttggcttcaa gaaaaatgga gagagtaaac tctactatac
    51601 agatatcaac agcaggaata tcacctggtg gaggtgttgg caatactaga aaatctctaa
    51661 ctaaagaaac tttaggcgtg gatgttattg caataggcgt tccaacggtg gttgatgcag
    51721 caactcttac aatagatgtc ttagatatgg caatagacaa tttaatagct caatcagaag
    51781 aaacagaaag tttttatgaa atgttgaaaa aacttaaaga agaagaaaaa tatcatctaa
    51841 taaaagattc gttagaccca tatgacaaga acttaatagt aacaccaaag gatatagatg
    51901 atacaatcga aaatctatct ataataataa gtgaaggctt aaataggtct ttacatccag
    51961 gtagattggt ataaaataag gaggagcaat tatgtttaaa aaatgcatta aagtagtaac
    52021 cttgactttt atattagtat gcattttacc aggaaaatca ttagctttga atcaagatga
    52081 ttttttaaag tttttagtaa attcatctta tccagaagct aaagtcgaag gaaatgatac
    52141 agaaaataaa aagaataata aaaataaaga aacaagtaag gaaaataagg aagaaagtaa
    52201 agaaggaaac actaaatcta aagatgcaag taaagttgat aataaaaaag agagtgaaaa
    52261 agaatatata aaactttatg ttggtaaaga aaatgttcca gatattgagt caaaaaattc
    52321 agacacaact gaaactaaca caacatctag ttcagattat aaggatgatt taagagtaac
    52381 caaagaaaat ccaagaattt tgatatatca tactcatgga tgtgagactt attcaaattc
    52441 acctgatgga aattatcatt caagagataa gaaaaattca gtaatggaag taggaagtgc
    52501 attaactagt gctttagata gcaaaggatg gggtgtagtc catactacta aataccatga
    52561 ctatccatct tataataact cttatgcaag tagcttaaaa acaatacaaa gtatattacc
    52621 taaatataac tcagtggata tagcgataga cttacataga gatgctaggg atttaactaa
    52681 tccagccact aaggaaaaag accatttaaa atatacaact atgataaatg gagagagagt
    52741 atcaaagttc ttctttgttg taggaggtaa aaatacaaat agaaaacaac ttagagcttt
    52801 agcagaagat ataactgctt ttgctgagaa aaagtatcct ggtctagtat ctccaatagt
    52861 agaaaaagac tatgctagat tcaatcagtt tgcagttaag aatcatatgt tagtagaaat
    52921 agggaataac gcaacaagtg tagaagaatc taaggctact acaaagtatt tagccgagat
    52981 tttggatgaa tattttaaac aaaaaaatta gagctttaag ttataattag gagcatgcta
    53041 aatgagccga ttagaaaaaa atatagaaag taaaagtaaa ctaagaaaat acaagtatat
    53101 tatgagaatc ttatttttga ttactatgat tatatgtaca tcagtttgtg tatttatagt
    53161 ggacagtaat gcaaaaagta tgctaggaat gaaacaatat gattttccaa gtattaaatt
    53221 tgatataaca aaatttgatt ttgacatacc aaattttgat atacatgaaa tcataaaaaa
    53281 atttaataag tagtaataag tgaataaggt ttattgatta aaataagcct tattttagtt
    53341 atatattttt aatgtataaa ataaaaattc attaactgta ttttatagga tttactttaa
    53401 gtttatgata ttatataata tttagtgtta gacttgataa tccacatata atgtggataa
    53461 ttttgtttag tgccaattag tttatattca aaaattttaa atttggtata taaagagttt
    53521 ttagataatg taaaataata actataagaa taatcaagag gagggaattt taaggtggac
    53581 aataaacaaa gtagaactag aaattttagt ataattgcac atatagacca tggaaagtct
    53641 accttagctg atagattaat acaacaaact gggcttgtta gtgaaagaga catgaaaagt
    53701 caattacttg acaatatgga ccttgaaaga gaaagaggaa tcactataaa gcttcaaaac
    53761 ataagattaa tgtataaagc gaaggatgga aatgaatatt atttaaatct tatagataca
    53821 cctggacatg tagactttaa ctatgaggta tcaagaagtt tagctgcatg tgaaggagca
    53881 ctattagtag ttgatgcagc tcaaggtgtt gaggcacaaa ctttagccaa tgtttatctt
    53941 gctatagacc aagatttaga aatattacca ataataaata aaatagattt accaagtgca
    54001 agaccagagg aagtaaaaaa tgaaatagaa gatttaatag ggcttgattc aagtgaagct
    54061 cctcttattt cagctaaaac tggtttaaac atagaagatg ttttagaaga tattgtaaaa
    54121 aatgttcctc cacctaaagg agataatgaa gctccattaa aggcattaat attcgattct
    54181 tactatgatg cttacaaagg tgttgtagct tatgttagag tatttgaagg aactgttaaa
    54241 aagggtatga caataaaaat gatgaatacc aataaaaagt ttgaggtaac tgaagttggt
    54301 gttatggctc caggtcaaac tgaacttagt gaattatcag caggtgatgt tggttatatt
    54361 gctgctagta taaaagatat aagaagttgt cgtgttggtg atacaataac agattcaaat
    54421 aatcctacag aagaaccttt accaggatac aaaaaagcta ctccaatggt atattgtggt
    54481 atatatccag gagaaggaga aaagtatgag aatgttagag atgctcttga aaagcttcaa
    54541 gtaaatgatg ctgcacttga atatgaagct gagacttcag cagcactagg atttggtttt
    54601 agatgtggtt tcttaggtct tttacatatg gagataatgc aagaaagact tgagagagaa
    54661 tttaaccttg atataattac tacagctcca tctgttatat atagagttac aaaaatggat
    54721 ggagaggttg taatgataca aaatcctgca aacttaccag aaccatctga gataaagatg
    54781 atagaagagc ctatagtaaa aggagatata atagttccta aagactatgt gggtgttgtt
    54841 atggagcttt gccaggaaag acgtggaaat atgttaaata tggaatatat agatgataga
    54901 agagtaatgc ttcactatga ccttcctctc aatgaagttg tttacgattt ctttgatgct
    54961 ttaaaatcaa gaactagagg ttatggttct cttgattatg aggttaaagg ttatgtagca
    55021 tctacacttg taaaacttga tatattaatc aataaagagc aagtggatgc acttagtttt
    55081 attgtccatg agacacgtgc tttccctaga ggaaaggcaa tgtgtgagaa attaaaagga
    55141 gaaattccaa gacatcagtt tgctatacca atacaagctg ctgttggtaa taaggttatt
    55201 gcaagagaaa caataagcgc tctaagaaaa gatgttcttg ctaaatgtta tggtggagat
    55261 atatctcgta agaagaaact tcttgaaaaa caaaaagaag gtaagaagcg tatgagacaa
    55321 attggttctg ttgaagttcc tcaaaaagca tttatgtctg tgcttaaatt agatgagtaa
    55381 atccttataa atttagataa agatatttaa aagctagagt gattttagaa ttatttctaa
    55441 attagtctag cttttttatg gtatatttta agtaaactca tagagaatat aagtaagaat
    55501 attaaagaag aataaaaagg tgatatttat gattaatata gaaattccta aaaaagtaga
    55561 ctatataatt aaagaattag aaaagaatgg ttatgaagct tatatagttg gaggatgtgt
    55621 tagagattgt ttattagaaa gagttccaaa cgattgggat ataacaacta gtgctagacc
    55681 agaagtggta gtagaattat ttgaaaaaac aattccaact ggtatacaac atgggactgt
    55741 aacagttatg attgaacatg aaccatttga agtgacgact tatagaattg atggaaatta
    55801 tagtgatggt agacatccag attcaataga atttacaaat aacatagtta aggacttgtc
    55861 aagaagagat tttactatca attcaattgc atacaattca aagacaggat tagtcgaccc
    55921 atttaatggc tatgaagata tacaaaataa gtatatacgt tgtgttggaa atccagtaga
    55981 tagatttgaa gaagatgcac ttagaatgct tagagcagtt agattttcag cacaactcaa
    56041 ttttaaaata gctgaaggta ctaagcaaag tattcataaa aaagcagatt tgataaaaaa
    56101 tgtttctatt gaaagaatcc agacagagtt taataaaata ttagtatctg attcatctaa
    56161 attaaactta ttaaaatcaa caggtttgtt gaaatttata attcctgaaa tatgtgaatt
    56221 agaagatgtt actcaacaca atccatatca catctatgat gtacaaaaac atactttaat
    56281 agctacagaa gtaattgaag atgaactgta tttaaaactt acaatgttgt ttcatgattt
    56341 aggtaaaaaa gtaactaaaa caactgataa aaatggtgtt gaccattttt atactcatag
    56401 tagagaatct gtaaagattg caaagaagat tttgaaaaga cttaagtatg ataattatac
    56461 tattaataaa gttttaatat taatacaata tcatgattat agaatagaac ctaaaaggaa
    56521 gataattaaa aagttattaa ataaacttga agatgttgaa ttatttgaag atttaataaa
    56581 agttaattgg gctgatacac ttgcaaaaaa tccaaagtat gcaaaacaaa agatattaaa
    56641 tcttattgag tgtgaaaaag aatttaaaca tataataaat caaaaggagt gctttaatct
    56701 taaagattta gctattaatg gaaaagattt gatatctata ggtataaaac caggtaaaga
    56761 tataggatat attttaaata agatgcttga aatagtcata aataatccag agttaaatga
    56821 aaaagaaata ctaaaagaaa aagcattaaa tatatataca ttttagattc aaatataaaa
    56881 aatttaatta ctttaaaaaa catagaataa aatacttatt tagataaaat aaataatttt
    56941 tagagaatat tttagaagtt acgattgtat gatttttaaa tgcataggca tttactctag
    57001 gactatagac taatataaaa aaaaactttg ggaatactaa aaccataaat ttataaaatt
    57061 aatattttat atactgtaaa acagtgagga gggacagtat gcatactcaa ctacaaaaga
    57121 ctattggtct ttcagcagct ctttctactg ttgtaggtat ggttataggt tcgggagttt
    57181 tttttaagcc acaagcaata tacactacaa ctaatggagc tccaggtcta ggtattatag
    57241 cgtggctttt aggtggtttt ataacaataa ctgctgggct tacagctaca gaaatttcag
    57301 ctgctatacc aaaaactggt ggtatgatga tttatatcga agaaatatat ggagaaaagt
    57361 taggtttttt aactggatgg atgcaaactg tattattttt cccaggtaca tcagcggcat
    57421 taggagtaat atttgctcaa caagcatctg aacttttagg aatgagccca aataatatgg
    57481 caaatgtact tcctatagca attggagtta tactattttt agcgttatta aatataatag
    57541 gttcatcctt aggaggaaaa gttcagacag tagccactat tggaaagatg atacctttaa
    57601 ttttaataat agtctttgga tttattaaag gtcaaagtag tgaagtatta aatccatttg
    57661 taggagatgg tgtaaatgca tcaaatgcac ttggacaagt attaatagct actttgtttg
    57721 catatgatgg ttggataaat gttggagcta tatcaggaga aatgaagtct ccagagaaag
    57781 atttaccaag agcaatagtt ggtggtttat cattagttat ggcagtttat attataataa
    57841 atatagctta tctttgggta gtaccagcaa gtgaattagc aacagttact tccccagcta
    57901 cattagtagc aacaagattg tttggaaata taggtggaaa agtaataact gtgggtatat
    57961 taatatcagt atttgggaca ttgaatggat atttattaac aggttcaagg ataccttata
    58021 cattagctga aatgggaact ttaccagcat ctaaaactct tttaaaagta aattctggag
    58081 gttctcctgt aaattcaata ctacttataa ctgtgttagc ctgtgtatat gcattatctg
    58141 gtcaatttaa tcttttgaca gacttaacaa tattttcaat atgggtattt tatgtattga
    58201 cttttatagg tgttatgagg cttagaagac aaaagccaga tttacacaga ccatataaag
    58261 tccctttata tccaataata ccaattatag ctatattagg tggactgttt gtaataataa
    58321 atcaaatatt gacttcaaca gtcatatctt taggcggaat atttataaca ctattaggtt
    58381 taccagttta ttattatatg aaaaaaagat aactacttaa tttaagttag ataaatttgg
    58441 gtaaaggtga aaattaactt ttatccaaat tttttatact gttatacaat ataagtatta
    58501 tatattgctt gatgtgctat tttgtttgat ttataattta gtaattgatg ttttaagata
    58561 atttaagaaa tgaggagtga aagatgctag gactttatgt acatattcca ttttgtgtga
    58621 aaaaatgtaa gtattgtgat tttaattctt ataaaatgga catagattca aaaaaaagat
    58681 atatagaaga cttaaaaata gaaatggaat tatatagtaa taaattatat aaagataata
    58741 aatataaaaa taaagaatgc tgtagtctaa ataaaaatga caaaataacg agtatatttg
    58801 tagggggagg tacacctagt atactaacct ctgatgaaat aagagaagta tttataagta
    58861 taaaagaaat gtttgatata gatgagaatg cagaaataac tatagagtgt aatcctggga
    58921 cattaacatt agaaaaatta aaaactatga aagagattgg cataaataga cttagtatag
    58981 ggctacaagc tattcaagaa aagcatttga actttatagg aagaatacat acttatgaag
    59041 aatttgagaa aaactataaa gatgcattaa gtgtaggttt taaaaatatt aatatagatt
    59101 taatgtacag tcttccaaat caaactctat gtgattggaa ggaaactctt gaaaaagttg
    59161 tacacttaaa tccaacacat atatcagctt attcccttat actagaagaa ggaactgaac
    59221 tatacaatat gtatgaaagt aataaatttg aacttataga tgaaaatgta gatatagaaa
    59281 tgtatgagta tacaataaac tacttaaagt caaaaggata taatcaatat gaaatatcca
    59341 actactcaaa agaaggctat aattgtgagc ataatatttt atattgggaa tgtgaacatt
    59401 atatagggat tggagcagga gcttctggct atattaatga gaacagatac aataatgtag
    59461 aatctttaga agattatcat ttaagtttgg taaaaagaga aaaaccaata caagaaaatg
    59521 aaattctttc tgagaaagat atgatagaag aaaagatatt tatggggctt agaatgaata
    59581 aaggcataaa atttgaagat tttaaaaaaa aatttggaat agattttaga gagaagtata
    59641 ataagcaaat agaaatgcta ttagctagaa agcttataaa tcagagcttt gaaggtatac
    59701 aattaactca aaaaggaaga gaaatatcta atagtgtatt tatagaattt atggaataat
    59761 ttttaaggtg ttgacaaaat aaatttataa tggtatataa tatatataat ctttttagca
    59821 ctcgaactta gtgagtgcta acagctagga ggtataataa tatggaatta aatgaaagaa
    59881 aattaaatat cctcaaagct atagttaaag attatataga aacagctgaa gctataggtt
    59941 ctagaacaat atctaaaaga catgatttag gtgttagtgc tgctaccata agaaatgaaa
    60001 tggctgacct tgaagaatta gggtatttaa ttcagcctca tacttctgcg ggtagagttc
    60061 catctgaaaa aggctataag ttatatgtaa actctcttat gagtaaaagc gaattggatg
    60121 ataatgataa gattcttatt gaacaatgta tgaatcacaa tataaatcat ataaaagaat
    60181 tgattcatga aacttctaag ctattatcgc aactaacaaa ctatacaact gtagcagtta
    60241 ctaagagttt aataaatcaa agtgttataa agcacataca gttggttgct atgaatgaca
    60301 ataatatttt acttatagtt gtaacagata aaggggactt aaaaaaagct aaccttacaa
    60361 ctaatgtata tttagatcaa tctaagttaa atttgatttc tgataatctt acaaggaagc
    60421 tcttaggtaa aagtataaca gatttggatg ataatctaat tgcttttatt aaatacgaaa
    60481 taagtgagta ttctgggctt atagatgagc ttttaaatgc tttgaactca aatatgaaag
    60541 aagaagattt ttctctatca ttaaatggag ctactaacat atttagttat ccagaattta
    60601 atgatgtatt aaaagcaaag tcatttttaa atatgttgga aaaaaaggaa acaatagctg
    60661 acataattaa atcaaaggga atacaaaaag acaatctaaa tataataatt ggtagtgata
    60721 atgattgtga actggcacag gattgtagta tagttacagc aacttataat gtagatagag
    60781 acttggttgg gcgaataagc tttataggcc ctaccagaat ggattatgct agaatttact
    60841 ctataataaa ttatatgagt ttattaatta atagaaagta aagaaatttt aaattgcgag
    60901 gtgtaaagtc ttggataaaa aaaatgagca acaggaagta agagaagaaa atgatacttc
    60961 tattaaccaa gaatcggaaa ctcaagtaga gttagaagag gaagttgtta atgaagaatg
    61021 tgaaacatca agtgaaaaaa ctgatgaaaa agaagttgat gatgaaaatg taacagatat
    61081 aaattctaag ttagcagaaa aaaaattgca ggatgagttg gatgaattaa atgataaata
    61141 tcaaagactt caagccgaat atgcaaacta cagaagaaga actcaacaag agaaagagac
    61201 aataggcgta tttgcaaatg aaaaaataat aactgaattg ataccagtta tagatagtat
    61261 ggaaagagcc ttagatgcat gtgaagataa ggaagatact atgtataagg gtataagcct
    61321 tgtacataaa caattaatag acactttagt aaaatttgga gtagaagaaa tagaagcaga
    61381 atctaaggaa tttgacccta atctacatct agcagttatg caagaaagtg tagatggagt
    61441 tgaagcaaat caaatagtaa tggtacttca aaaaggatat aagctaggaa ctaaagttgt
    61501 aagaccttca atggttaaag tttcttgcta agtataaatt aaaggttaaa ttatttaacc
    61561 taatataaaa tattaaaata agtaaaactt aattatataa ttactcgagg aggattttag
    61621 tcatgggaaa aataatagga atagatttag gaacaacaaa ttcatgtgtt gcagtgttag
    61681 aaggtggaga agcacaaata atagcaaata gtgaaggtat gagaactact ccatcagtag
    61741 tagcatttac aaaagatggt gaaagaatag ttggagaacc tgcaaaaaga caagcagtta
    61801 caaatgcaga taaaacaata acttctataa aaactcatat gggaactgat tataaagtaa
    61861 atatagatgg aaaatcatat actccacaag aaatatcagc aataatatta caaaaattaa
    61921 aatcagatgc agaaagttac ttaggacaaa cagtaacaga agcagttata acagtaccag
    61981 cttactttac agatgctcaa agacaagcaa ctaaagatgc tggtagaata gcagggcttg
    62041 atgttaagag aataataaat gagccaacag cagcagctct tgcttatggt atggataaat
    62101 tagaccaaga aaagaaaata ttagtatttg acttaggtgg aggaactttt gacgtatcta
    62161 tacttgaaat aggagatgga acttttgaag ttttagctac agctggtaac aatagattag
    62221 gtggagatga ctttgaccaa atagtaatag attatttagc agaggaattt aaaaaagctg
    62281 aaggtgtaga tttaagaaat gataaaatgg ctcttcaaag attaaaagaa gcagcagaaa
    62341 aggctaagaa agaattatca tcaacaatga gttcaaacat aaacttacct ttcataactg
    62401 ctacagcaga aggaccaaaa cacttaaata tagatttatc aagagctaaa tttgaagaat
    62461 taactagagg tttagttgaa aaaactatgg aaccaactaa gacagcttta caagatgcag
    62521 gactttctac aggtgatata gatgatgtat tattagtagg tggttctaca agaataccag
    62581 cagtacaaga agctgttaag aagtttatag gaaaagaacc tcataaaggt ataaacccag
    62641 atgagtgtgt tgcagcaggt gcttctatac aagctggagt tttagcaggg gatgttaaag
    62701 acttattatt actagatgtt actccattat ctcttggtat agaaactatg ggtaatgtaa
    62761 tgactaagat aatagaaaga aatactacaa taccaactaa gaagtctcaa atattctcaa
    62821 ctgctgctga taaccaaaca gctgttgata tacatgttct tcaaggtgaa agaagtatgg
    62881 cttatgacaa tacaacttta ggaagattcc aattaacaga tataccacca gcacaaagag
    62941 gaatacctca aatagaagtt acttttgata tagatgcaaa tggtatagtt aatgtttcag
    63001 ctaaagattt aggtacagga aaagagcaaa aaataactat aacatcaaac actaatttat
    63061 cagaatcaga aatagagcaa aagataaaag aagcagaaat gaatgcagaa gctgacaaac
    63121 aaaagaaaga aaaaatagaa gcattcaatc aagctgaatc tactatatat caaactgaaa
    63181 aaactttaaa tgaacttgga gataaaataa gttcaggtga aaaagaggat atagaaaaag
    63241 ctatagcaga cttaaaagct gtaaaagata atcaagatgc tacagcagaa gaacttaaga
    63301 aagctacaga tgaagtaatg actaagttcc aaaaagtatc tcaagaaatg taccaaaaag
    63361 cagctcaaga acaacaagcg gcacaaggtg cagaacaagc acaagacaat ggacctaaag
    63421 atgacaatgt agtagatgct gactttaaag aagtagatga agataaataa gctatataat
    63481 atgtaacact aaatgataat tggaacatat atgatttgtg aaaatcatat agatgttaaa
    63541 gatatatgga caatatacat cataaagaat ataatatatc atagattata taacttaaag
    63601 tagaatataa gaattaatga tagcttgtag tttattattc tacaagctat cgttttgtaa
    63661 aatgaaggtg gtgtcaattt ttgagtacaa aaagggatta ttatgaagtc ttaggtatca
    63721 gtaaaggtgc agaagctcaa gagataaaaa aagcttatag aaaattagca atgaagtacc
    63781 atccagatag aaatcctgga gataaagagg cggaagaaaa atttaaagag ataaatgaag
    63841 cttatgaagt tctatctgat gatacaaaga gaaaaactta tgaccagttt ggacatgatg
    63901 ggctaaatgg tcaaggcggt tttggtggtc aaggaggatt tggcggtcaa ggctttggtg
    63961 gttttgaaga tatgttcgga gatatatttg gtgacatgtt tggaggaagc ttcggaggtg
    64021 gaagagcaag aagaagaggg cctcaacgtg gtgcagatat aagacagagt gttactatat
    64081 cttttgaaga agctgcattt ggtaaaaaga tgtctataaa agtaaataga agtgaagaat
    64141 gtgaagaatg taatggaact ggagcaaaac caggaacatc aaagaaaact tgttcaactt
    64201 gtaatggaac tggtcaagtt agaactgttc aaagaactcc atttggtaat atagcaagtt
    64261 caagaccatg tagtgcttgt aatggaactg gagaagtgat tgaatctcca tgtagtaaat
    64321 gtcatggaac tggaaataca agaaaagtta agactataga agtagatata cctgctggta
    64381 tagatgatgg tcaaatgata aaactttctg gtcaaggtga agtaggagaa aaaggtgctc
    64441 caagaggaga cttatatatt gtagttaatg ttaagtcaca tccactattt actagagatg
    64501 gaaatgatat ttattttgaa atgccaatta catttgttca agcaacttta ggtgatgaga
    64561 tagaagtacc tactttggat ggaaaagtta aatatagtgt gccagagggg acacaaactg
    64621 gaactgtatt tagacttaaa gagaaaggaa tccctagaat tagaggtaat tcaagaggag
    64681 accaatatgt taaggttgta gttgaaattc ctaaaaaatt aaacgataag caaaaagaac
    64741 tattgagaga atttgcgaag gagtgtgggt cgaacgtcca cgaaaagaag aaaaccttcg
    64801 gacaaaagat agaagatatg tttaagaaaa agtagttaaa gtagccaata tataatcata
    64861 tttttaaaat cttagttatt tataagattg tcaaaggaga tattatgatt tttatattgg
    64921 ctatttttgt ataaaaaata aatgtgcata aaataaaact gaatataaat aattttctga
    64981 aaaatacttg tcctaaaata tataatatgc tataatataa tcaaataaaa gaaaggggtg
    65041 attccagtgg gaacggatgt ggcactgcca aatgatgaag aaaactttat tgtaatatac
    65101 aaaataaaat tagatacttt tagtgctaga ttaagtactg gaaaaactca tgagctggga
    65161 taattattgt aattacctag actcaaactt ttagtagtaa aatagtaata ttatatagac
    65221 aaggtatcta atttttaaat cttttgtatg aattaaaatt tttataaagg gtatatctga
    65281 ttagaatgta attagggaaa cctagttgtg aattactttt agtatataca tgtgtaaaga
    65341 aatatgtata tggtattggg tattgtgcta gatgtgtatg taaaggaata tgtgtctagt
    65401 tgggtatatg taaagaaata tacttataat ctatgaaaaa tttttagtat aaattgctaa
    65461 aacattgaga ttgtttttta tagaaagtta gtttatacca actaaaaatg tgcttaagat
    65521 ttgtttgatg tttaattata aataaggttg tagataaaaa aataagtaaa gacaaaggtt
    65581 taaaatactt gctttaaata tagtttgttt tgaacacttg ccaaattaaa ataattaata
    65641 aaatagacat cttctcatag taaaatatac tgtgagagga tgtttttgct ttgttcataa
    65701 acttttatga aaaatttgca tagtgtcaca ttttaatata ctatatatat aataaaatat
    65761 agataaaatt aaatgattca aaagagaaag gtgaaaagag atgtattata taggtgtaga
    65821 cataggagga acaggtatac aagcaggagt agttgataac tatgggaaga taatttttag
    65881 gtcagagtgt aaaacagtaa ttgaaaaagg atttgaagga atacttaatg acataaaaat
    65941 aatgatttat aagttgttgg aagataataa acttactatg agtgacataa aatctattgg
    66001 atttggtgtt ccaggtttta taaataaaga aggattagta acttgtgtaa atttaaaatg
    66061 gaataaaaaa gcttttaata aagagttaaa aaaaagattt ccagatgttg aaattcatgg
    66121 agaaaatgat gcaacagtag cagcacttgg agaagcaaag tttggaagta tgaaaggtgc
    66181 taatgttgga gtattatata ctttaggaac tggtgtaggt ggaggaatag taattaatca
    66241 aaaagtcttt tctggagcac atggattggg ttcagaaata ggtcatcaaa ttataggaga
    66301 aaactatttt aattgtaatt gtggaaataa tggttgtgta gaaacttttt gttcagcaac
    66361 tgcaattata aagtattctc aaaaactgat agaagaagga gaaaagagta ggattttaga
    66421 tttggcagag ggaaatttag aaaatgtaaa tgcaaagatg gtgtttgatg catatagaga
    66481 aaatgattta gtggcaatta aagtaataaa tagatttaaa gagtatttag caaaaacttt
    66541 tgcaaacaca ataaattctt tagacccaga aattatatct ataggaggag gcatttctaa
    66601 atctagcgat ataatacttg atggaataga aggtttggta agaaaatttg tattatacaa
    66661 aacagaagat atagctacaa ttacatgtgc aactttaggt tcagacgcag gaattatagg
    66721 agcagctttt ttataatgta aatgaactgc ttattggagg cgtgatgata tatgggtaaa
    66781 acaaatgcta gaagaacgct ttttttgata gcaataggtt caggaactat gctgaatcct
    66841 cttaattctt ctatgatttc acttgcttta catagtatac aaaatgattt tcatattagt
    66901 tttacaactg tatcttggat tgtttcagca ttttacctag ctagtgctat tgcacaacca
    66961 gtttcaggta agataggaga tttaataggt agaaaggtct tatttttgag tggtttgatg
    67021 cttgtaattt tatcagcatc catagtacca cttgttcaat cattctttat attgattttt
    67081 ataagagtaa ttcaagcaat tggaacaagt accctatatc catctggagt tgctcttata
    67141 caaaataata taaaagaaag acaatcttct gcattagcag ttctaaccat ttttgcttca
    67201 actacagcag gattaggtcc gacacttgga ggattattgt tggacttagg aggatggcat
    67261 gctatatttc ttgtaaatat acctgttgtt ttggtttcta tatgcttagg gtatttttta
    67321 ttcccaaaag aagtaaaaga aaagaaatct ataaaagaaa ctttaaaaaa tgttttgtca
    67381 agattagata ttattggcat acttctattt tcaattgcaa tgatttttat attactattt
    67441 ttgctatcta tgaaggaatc ttttaactta gaacaacttg tatttggtat aatactgatg
    67501 tgtcttttta tttggcatga attgagaaca aaattgccat ttatagatat taagcttttt
    67561 gtaagtaatc ctaaattgtc aaaagtttac ttgcaattta ttatattaaa tttctttaat
    67621 tatattttgt tttttggtct tcctagttat tttcaagatg ccttacatta tagtgcaaag
    67681 tcgactggat tatttatgct atttatgtct ggtataggta tatttatatc tccattaact
    67741 ggaaaatgga tagataaatc tggaactaga tttcctcttg ttacatcatc aatctttatg
    67801 tttattagtg cagtacttct ttcagtagtt tttatccata tacctgtaat aggaaagggt
    67861 attatattat cattagcagg tattagttat ggagttggta atgtagccct gcaatcctct
    67921 atgtttgaag aaagtcctcg tgacagtata gggacagctt ctggtctgtt tcaaactagt
    67981 cgttatttag gttctatttt agcaactgtt ttacttggaa tggtatttga agtaaatata
    68041 acatcagaac aatttcagat attaggttat gttatggtgg tcttaggtac aataagtttt
    68101 ttattaaatt ttatattaaa gaaagaatta agaaaagtag aatagtggat ttatggattt
    68161 aataagtcta ataactgata agtttaaaaa tattgtttgt aaaacataac tggtttgata
    68221 tttattaatt ctaagttttg aagcatagag tactcgataa gtatacaata ttttgaatta
    68281 aaattaagca gaaatttgaa ctagtctttc aaatctctgc ttaatttagt agttaaattt
    68341 ttttatagag aaaataagat ttgacactta gataaaaaat cattgcattt tcaaaattct
    68401 ttaaatcaaa cccaagtatc tcattaatct tttccaatct atatactagc gtgtttctat
    68461 gtaaaaacat actagtagat gtcttagaaa tatttaaatc attatttata aattttattc
    68521 ctgtatatag aagttcttcg tcaatagatt taatcttatt aaaatctatt aatttattga
    68581 gtatattatc ctcattaatt aaatctaaag ttttatatct aataaggtca aacaaattta
    68641 aaaacttatt ttcagcgttg tcttttataa tatgaggtag taaatcagaa cataactgta
    68701 atctaaaatc aaaatcagct ttactatcta attcaccaag ataaaaaata taagtacttt
    68761 gataagtttc agtttcaatt atattttgtg tagttacatt aatatctaag ttatatttag
    68821 aatttactat aaaaaaacca ttgtgttgta ttatatttat atcttcaaat aaattataaa
    68881 aaatattttt tagatattca aagtctatat gagattggta aattaaataa aagttgcctt
    68941 ttaaattatc gagattattt ttatctagaa aatcaataac ataaatagca ttattgaaag
    69001 taactaaatg gctactagca tctaactttt ggttttcata tggatagata tttatttttt
    69061 tattaagctg tctttctaaa aaatctttta actcttccat aaagtctcct taaaaataag
    69121 attatattct tatcttatag ctaaagtagt ttctttgtca aatatgtgta ctctactatt
    69181 gtcaactgaa agtgttaagt catcaccaac attaattctg tttttactgt caaatctaat
    69241 tgttatcgta ttttcgccta gttttaagtg agcataagtt tctgctccca taagttcttt
    69301 tatttcaatt cttgatttaa aacaagtatc tggattagat ttaataaaag tatcttctac
    69361 atgaatatct tctggtctga tacctataac aacttcatta ttaatataat tgtcttttat
    69421 taaatcatag tgtttttctt tattcaattt aagcttaata tgttcatttt gtgcataaat
    69481 ttcatcattt tcttctatta atattacatc aataaaattc atctgtggtg ctccaataaa
    69541 tcctgcaaca aatatattag ctggataatc gtatacatct tgtggagttg caatctgctg
    69601 aactactcca tccttcatta ctacgattct atcagccata gtcatagctt caacttggtc
    69661 gtgtgttaca tagataaatg tagttccaag ctgttggtgt agcttagtta tctctgttct
    69721 catagcagtt ctaagttttg catctaagtt ggatagaggt tcatccatta agaatacctt
    69781 aggatttcta actattgcac gtcctaaggc aaccctttgt ctttgtcctc cagataatgt
    69841 tttaggtttt ttatttaaaa gaggtagtaa gtctaatatt ttagcagctt ctttaacttt
    69901 tttgtctatt tcatctttag gcaattttct aagtttaagt gcaaatgcca tgttttcgta
    69961 aacagataag tggggatata aagcatagtt ttgaaaaacc atagctatat ctctatcttt
    70021 tggttctata tcattgacaa gtttatctcc aatgtatagt tctccttcag agatttcttc
    70081 aagaccagca atcattctaa gtgtagtcga tttaccacaa ccagatggtc ctactaaaac
    70141 gataaattct ttatctttaa tgtctatatt tatatttttt actgcattaa atccatttga
    70201 gtaaagtttt gatatatttt ttaaaattac ttctgacata atatcctcct tgatatttaa
    70261 attttaatta tatagtatca aattttttta ttatattaaa tgtgtaaaat gactaaatgt
    70321 atttgtttaa tatgtata
//
LOCUS       DAEPHU010000011        69488 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 01A10CD0081
            SAMN05941466-rid12468953.denovo.011, whole genome shotgun sequence.
ACCESSION   DAEPHU010000011 DAEPHU010000000
VERSION     DAEPHU010000011.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941466
            Sequence Read Archive: SRR6291087
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 69488)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 69488)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068158.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 22:43:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,892
            CDSs (total)                      :: 3,805
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 87
            rRNAs                             :: 8, 1, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 55
            CDSs (without protein)            :: 55
            Pseudo Genes (ambiguous residues) :: 0 of 55
            Pseudo Genes (frameshifted)       :: 21 of 55
            Pseudo Genes (incomplete)         :: 28 of 55
            Pseudo Genes (internal stop)      :: 16 of 55
            Pseudo Genes (multiple problems)  :: 8 of 55
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..69488
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941466-rid12468953.denovo.011"
                     /strain="01A10CD0081"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            403..1605
                     /locus_tag="KR231_000778"
     CDS             403..1605
                     /locus_tag="KR231_000778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine kinase"
                     /protein_id="HBH0003184.1"
                     /translation="MKTSILIALIEKTSLIVVLFLLITKLKIFKQIFQKEEYSFNDLV
                     CIALVFTFLAIFGTYSGINYMGSIVNTRIISIVSGGILFGPMVGITAGVFSGIHRYFM
                     DIGGITSVPCLLSSILAGVLSGFLYKRIPKQHRVMYGILVGMISESFTILLIYLISYP
                     HSLAIQIIGGIYLPLIVGQIGIGFVISIVEGIEKDKKDIEARNKAEIKALQRQINPHF
                     LFNSLNTIASFIRFSPDKARELIINLSTYLRYNLEYSDNLIDINKEIEQVKSFVEIEK
                     ARFGELLTVSYDIEDVNIKIPSLIIQPLVENAIIHGILESGRAGVVKISIKKLPYSLE
                     NTVRISIEDNGIGISEEIINNVYQDNMPENKIGLYNVHLRLKLMYGRGLNIRRIDNGT
                     LIVFYVKE"
     gene            1610..2380
                     /locus_tag="KR231_000779"
     CDS             1610..2380
                     /locus_tag="KR231_000779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001295458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBH0003185.1"
                     /translation="MRAIIVEDEFPARKELRYFIENKSGIEVVSEFTNGIEVLDFIQE
                     NKIDVIFLDINIPHLDGMLLAKTLNQFKSRPKIVFITAYESYAVDAFSLDVFDYILKP
                     YSEERIISMLNKLEKSEMSDIELFNVNSNLYKYKKEAVNQEIEEITHKISLWKGDKLV
                     VIDIDDIYYCEANERQTFIYTEKEKFILKEGISEVENLINDKTFFRTHRSYIVNLTKV
                     KEIIPWFNNTYILKLKNSDYEVTVSRSKVKEFRLLMHI"
     gene            2526..3947
                     /locus_tag="KR231_000780"
     CDS             2526..3947
                     /locus_tag="KR231_000780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbon starvation protein A"
                     /protein_id="HBH0003186.1"
                     /translation="MVSFLGSIVVLIVGYFVYGTFVEKVFGTNDKNQTPAIACRDGVD
                     YVPMKWKRIFLIQFLNIAGLGPIFGAIQGALFGPSAFLWIVFGTIFAGGVHDFASGYL
                     SMKNKGTSASELVGLYLGNGAKIAMRIFSVILLVLVGVVFVTGPAGLLKTLTGVNAQI
                     WVGVIILYYIMATVLPIDKLIGKIYPLFGAALLIMAVGVAGGLIIKGYNIPNINLQNM
                     NPNGTPLFPYLFITIACGAISGFHATQSPLMARCVEKESEARPVFYGSMVAEGIIALV
                     WAAAAMSYFHGIPQLNVIFNDGGAATVVNTVSVGLMGPIGGALAILGVVACPITSGDT
                     AFRSARLTIADAMNYNQDAVKNRFLIALPLFAVGVALTFIDFNIIWRYFSWANQTLAM
                     IMLWTGSAYLVKANKNHYITTLPALFMTVVTFSYIMQAKEGFRLPVNISNGIGVIVAI
                     ILGLLFFKKAKHIKEQNNHKLAS"
     gene            4213..4695
                     /locus_tag="KR231_000781"
     CDS             4213..4695
                     /locus_tag="KR231_000781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TraR/DksA C4-type zinc finger protein"
                     /protein_id="HBH0003187.1"
                     /translation="MDTKKYKDKLLKERENLTNLVEDMKDNTLFGDTTKHTSEKYSSG
                     ELSSYDNHIGDMGTDLYMQNMQNSLINHEEGRLYQIDLALSKIENGTYGICDLCHNQI
                     DLERLDILPDTSLCNDCAKKENNLLGDAMQNPDVEDSNFYSEDLTNLTDLNKNGILRD
                     "
     gene            4750..5529
                     /locus_tag="KR231_000782"
     CDS             4750..5529
                     /locus_tag="KR231_000782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HBH0003188.1"
                     /translation="MKKIIWGICICLLSIVGVYTYNHNTHNQDSSKEAYSLNDNIKDD
                     YEDVIIKKGNEDEKILALTFDDGPDEDFTPQVLDILKKNDVKATFFVVGEKVEYNKEL
                     LKRQYDEGHEIGNHTFTHINVAKNSYSSVEKEITDTQNIIKSVIGVEPKIFRPPYRAM
                     SKSVCDIIVSKGMNIILWSNLDPRDWSNPGVDAIINTILTKVQNGNIILLHDYNTKRN
                     DKSQTIQALEVVIPKLKERGYKFVTVSELIQHLDKNKQVQK"
     gene            5839..6285
                     /gene="lspA"
                     /locus_tag="KR231_000783"
     CDS             5839..6285
                     /gene="lspA"
                     /locus_tag="KR231_000783"
                     /EC_number="3.4.23.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase II"
                     /protein_id="HBH0003189.1"
                     /translation="MLYILIIILLIGLDQLSKIWVLNNLVDVSTIPIINNVFHLTYVE
                     NRGAAFGLLQNNQWIFIIVALLATVFGLYYLNTRKVHIFGRLGIILIISGALGNLIDR
                     VRLGFVVDYFDFRIIWEYVFNIADVFVVVGTVFLCIYVLFFESKSR"
     gene            6254..7201
                     /locus_tag="KR231_000784"
     CDS             6254..7201
                     /locus_tag="KR231_000784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HBH0003190.1"
                     /translation="MFYFLKVKVGDIMDEVKEFLVLEEEEEVRLDIYLAEQLGDMSRS
                     YIQKIIKDGKVKVNNKVEKARYLVKEEDNIVIEIPEPKVLEVLPQDIPIDIVYEDDDV
                     LIINKPQDMVVHPAPGNYENTLVNGILYHCKDKLSSINGVIRPGIVHRIDKDTSGLLM
                     IAKNNYAHNFLAEQLKEHTITREYEFICYGVVKEDKITVDKPIGRNPKDRLKMAVVKD
                     GKNAITHFEVVERFDKFTHMRARLETGRTHQIRVHALSINHPLLGDYVYGPKETKFKL
                     KGQTLHAKKLGFIHPTTKEYIEFNSELPEYFKEVIKKIK"
     gene            7561..8094
                     /gene="pyrR"
                     /locus_tag="KR231_000785"
     CDS             7561..8094
                     /gene="pyrR"
                     /locus_tag="KR231_000785"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001156491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional pyr operon transcriptional
                     regulator/uracil phosphoribosyltransferase PyrR"
                     /protein_id="HBH0003191.1"
                     /translation="MVEKAQLMDEKAIARAITRISHEIIERNKGVENLVLVGIKTRGV
                     PIANRISKKIEQIEGTKVDTGDIDITLYRDDLEKIHVEPVVKGTYLDFNVNDKTVVLV
                     DDVLYTGRTVRASLDAIIDIGRPKSIQLAVLVDRGHRELPIRADYVGKNVPTSRHEII
                     SVSLLEIDGEDSVTIKE"
     gene            8378..9589
                     /locus_tag="KR231_000786"
     CDS             8378..9589
                     /locus_tag="KR231_000786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil permease"
                     /protein_id="HBH0003192.1"
                     /translation="MKKTIMSLQHLLAMFGATVLVPILTGFNPSVAIFCAGVGTLIFH
                     FCTEGKVPAFLGSSFAFIPVILAAKEAYGGDLAYAQGGIIVAGLIYIIMSIIVKVVGV
                     NKIKLYFPAQVTGAMIVVIGLNLLPTAFSMASANFVIAFITLAIAILTNKFGRGFIKQ
                     LGILIAVFSGYIICLILRLVDITTITEASLFAIPNFTVPKFSLGAIVIISPVVLAVFM
                     EHIGDMTTNGAVVGKNFIENPGLNRTLLGDGFATIVAGCLGGPANTTYGENTAVLAIT
                     KNYDPSILRRTAIFAILLACVGKFGGFLQSIPGSVMGGISIMLFSMITYVGLKTIRDS
                     SCVESKINILIIAVILLIGLGTTYLSNKGISVGIPITSTVKITGLSLAAIVGIVLNRI
                     LNNQDFKVEEE"
     gene            9888..11540
                     /locus_tag="KR231_000787"
     CDS             9888..11540
                     /locus_tag="KR231_000787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HBH0003193.1"
                     /translation="MLLVKVENLKKYYADKLILDIDKLEILENDKIGLVGSNGQGKTT
                     LLKAILGEIEIDEGYTYLTESYSYISQSENNIETCSHSKEKSLLNAPDKFEEHLSGGE
                     KVKLKIADALSNKKNIIIADEPTSNLDKKSIGVLEDMFKRHEGALLLISHDRRFLDEL
                     CTTILELEDGKLKAYKGNYTDYLMQKDEEVKRADFEYQEYVKEKKRLEKALLYKKALS
                     DGIRKTPKRMGNSEARLHKMGGQTNKKKLDSNVKAIKSRIDKLEVKNKPKVSKEMNIK
                     MQDGMEIISKNLVEVKDMTLKLENKLLLDNVSFKIKRGKKIALLGDNGCGKSTLIKEI
                     LADKNDNIKINNKVKVGYFDQNQSLLDEEKSVLYNTKVNSSFDESFIRINLSLFGFKG
                     DDVYKKVKVLSGGEKVKIALCKIILEDNNFLVFDEPTNYLDIKSMEALEKALINTDKT
                     MLIVSHDRVFVSHICNYIIEIKDAKIREFDCNYDEYTISRNKKTPSRENQIKKENLLV
                     LENRLTTVISMLSIEKDNLKKELYESEYNELLKQINKLKNSF"
     gene            complement(11752..13527)
                     /locus_tag="KR231_000788"
     CDS             complement(11752..13527)
                     /locus_tag="KR231_000788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NFACT family protein"
                     /protein_id="HBH0003194.1"
                     /translation="MALDGLVIHSIVDELSSKLTGGKIDKIHQPEDDEVIFNIRNNKE
                     NFRLVLSASASNPRVYLTSNYQKENPLKAPMFCMLLRKYIQGGNIVEISQIGFERIIK
                     ISVESLDELKEKTVKNIMIEIMGRHSNIIITHGEENKIIDSIKRVPFSISRVRQVLPG
                     HDYSLPPEQNKLNPLDDISKDLFIKNLEELEGPIFKSIYSKFLGISPIIAKEICYRAG
                     VNQNAIIKDISDEQFDALHKVFCNLFNDINSNKYSPCIIIDKKVDKVVDFSCINLTLF
                     SDLSYINKDSMSRILEDFYRTKDIKDRINQRSSDLKKSISVKLDRLYNKLKKQEEELS
                     ESENADIYKIKGELITSYIYMVEKGMESIEVANFYDENCNDVTIELNKNLTPSENAQK
                     YFKKYNKMKHAKVEISHQISLNKEEIDYLENIILSIENCENLAELQDIKEELAKVGYI
                     KTQKKNSKKDTIPSTKPHEFVSSDGFKILVGKNNKQNDYLTLRLADNDDLWMHTKNIP
                     GSHVIIKCAGKEVPDNTVFEGAMLAAFFSKSKLSSQVPVDYTKRKNVKKPSGSKPGMV
                     IYETNSTIYVTPEEETVAKLKVKSE"
     gene            13823..14857
                     /gene="ltaE"
                     /locus_tag="KR231_000789"
     CDS             13823..14857
                     /gene="ltaE"
                     /locus_tag="KR231_000789"
                     /EC_number="4.1.2.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="low-specificity L-threonine aldolase"
                     /protein_id="HBH0003195.1"
                     /translation="MRFIDLRSDTVTMPTDEMREAMAKAPVGDSIFRDDPTVNKLEEL
                     AAAKVGKEDAIFLPSGTFGNQLALFTHCLRGQEIIIGKGYHIVTHEVGAPAVIAGVQL
                     RTIDEDESGALNPELVEKAIRRDDIHEPQTGLICVENAYSGGTVVSLDNLREIKKIAE
                     KHNLPVHLDGARLFNAALTLGVEAKEIAKCCDSVMFCVSKGLAAPMGSILAGNKEFIA
                     KARRKQKVMGGGMRQVGIVAAAGIIAIEKMTLRLNEDHENAKYLACELNKIDGIEVNN
                     VNPDISMVFFKMSEDIIKEDVLIKEFFERNIKINKMENGEYRFVTHVDITKEDLDYVL
                     KTLKELIGVC"
     gene            15144..15974
                     /locus_tag="KR231_000790"
     CDS             15144..15974
                     /locus_tag="KR231_000790"
                     /EC_number="5.1.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopimelate epimerase"
                     /protein_id="HBH0003196.1"
                     /translation="MKFWKLHGIGNDFIAIDGRFDQINPSDYTALAKKVCHRRFSVGA
                     DGLLVVKDSKVADVEMVYYNSDGSRAAMCGNGLRCFCKFVYDNCIVKKESFTVDTLDG
                     IKDIKVNLTNREINSIRVNMGKGSFIAKDVPVLTNKERFVQESIKVLDRELKVTSMLM
                     GVPHTVVIVDELDVDDVCKYGKEIENNKIFPEKTNVNFVKVEDKYNIHVYTWERGCGY
                     TLGCGTGMTASAIVCNLLNMVESSVNVTSQGGTVKIDVGDFSYMTGPAVKICEGILEV
                     "
     gene            15978..16859
                     /locus_tag="KR231_000791"
     CDS             15978..16859
                     /locus_tag="KR231_000791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YicC family protein"
                     /protein_id="HBH0003197.1"
                     /translation="MAISMTGFGRGEYKDDNYYFLVECKTINHKYSDINIRLPRKISF
                     LEDKVRNLVKNYVKRGRVDLYIKFDLLGKEDVNLNFDEGLASQYIDILKEIKNKFDII
                     DDISVMNVAKFPDIVKIEEKEEDEDLLWSMLNQAVEDALIKLREMRSEEGKKLAEDIA
                     MRCDLLKNHIEEIEKYSSSVVEDYREKLNLRISELLDDPSIIDENRLAQEVAIYADKS
                     SITEEIVRFKSHIGQLKNTIFKDDSIGRKIDFLIQEMNRETNTIGSKSSDINITNLVV
                     EVKSELEKIREQIQNIE"
     gene            16889..17506
                     /gene="gmk"
                     /locus_tag="KR231_000792"
     CDS             16889..17506
                     /gene="gmk"
                     /locus_tag="KR231_000792"
                     /EC_number="2.7.4.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="guanylate kinase"
                     /protein_id="HBH0003198.1"
                     /translation="MFVKKGLLLVVSGPSGAGKGTICKELLKENDTIKLSVSATTRKP
                     RTGEVDGVNYFFISKEKFEEMIEKGEFLEYAQIYDNFYGTPKAAIMECLEKGQDVLLE
                     IEMQGAKQIKEVCPEGVFIFVLPPSLEELKNRIVGRGTETEAEIEKRFSCAYEEIKMI
                     KDYDYFIFNEDVKTSAKEIEGIISSEKNKVSRYKNIIIEKFKEEL"
     gene            17509..17775
                     /locus_tag="KR231_000793"
     CDS             17509..17775
                     /locus_tag="KR231_000793"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit omega"
                     /protein_id="HBH0003199.1"
                     /translation="MLKPSINEVLEKIDNRYYLVGTVSKRARKLIDGEEPYVSNKTKE
                     KPVCVATKEVASGKITYRLLTEEEIEIEEARHHAEQHQQISEEE"
     gene            17780..18979
                     /gene="coaBC"
                     /locus_tag="KR231_000794"
     CDS             17780..18979
                     /gene="coaBC"
                     /locus_tag="KR231_000794"
                     /EC_number="4.1.1.36"
                     /EC_number="6.3.2.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890797.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional phosphopantothenoylcysteine
                     decarboxylase/phosphopantothenate--cysteine ligase CoaBC"
                     /protein_id="HBH0003200.1"
                     /translation="MLKDKTVVIGISGGIAAYKACDVVSKLKKLNANIHVIMTKSATE
                     FVKPLTFQSLSQNYVVEDMFEEPKTWEVEHISLAKKADLFLIVPASANVIGKIANGIA
                     DDMLTTTVMATKAQVLIAPAMNTNMYENPIVQKNIQTLKSFGYKFIEPESGRLACGDI
                     GTGKLANPDIIVEEVLTNLTKEQDLKGQSMIVTAGPTVESIDPVRYLTNRSSGKMGYS
                     IAREAIARGADVTLISGPTNLSIPQNLKKFVQIESAQDLYEAVVSNLSENKIVIQSAA
                     VADYKPKTYSDKKIKKKNDDLSIELSRNYDIAYEIGKIKEDKILIGFAAETNDLIEHA
                     KGKIKKKNLDFIVANDLTKEGAGFRADTNIVKIIDVEGNITEYPKMKKEEVANVILDK
                     VKALLEK"
     gene            19218..21743
                     /gene="priA"
                     /locus_tag="KR231_000795"
     CDS             19218..21743
                     /gene="priA"
                     /locus_tag="KR231_000795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein N'"
                     /protein_id="HBH0003201.1"
                     /translation="MNNILNLSRGFIMKKYAKVIVRSNTIYTDNLFTYQIPVFLSDVI
                     KIGHRILVPFGKGNKPTEAFVFQFTDSLDEKIKIKEIIDILDENPIFRKEDLELVYWM
                     KNRYLCTYIECINLIYPKGYKLNNYKVVLLGESLSGLNDIELKEKISTLSDKNREIVE
                     KVIDSKGKIKVDKLKYIPNLNSSLYTMNKNGIIKLCWEYKNHKNEKKVCYISLSLESD
                     KIDDYIEQNKINVGSKQKEILSFLKNNENVEINDLLDLLNASKQSINSLSKKKLITLE
                     FKDYYREPKSIYKSVLKSIKLNNEQQEAVDEIKSNMFVDDKKPYLIHGVTGSGKTEVY
                     MEIIEFALNQGLDSIFLVPEIALTPQTIDRLKSRFGDLVGVFHSKLSEGEKHDVYKAV
                     KAGKVRVLIGARSALFAPFNSLGLIIIDECHESSYKSEKNPKFNAIEVARFMALKNNI
                     TLILGSATPSIEEYYRAKSGEYKLINIKSRANDKPLPNIEVVDMKDELDKGNRSIFSL
                     KLQKEIRYAIEENNQVILFLNRRGYANFVSCRKCGYVFQCENCDISLTYHKKSNTGRC
                     HYCGYEKEIPKECPECKSTYVKPFGVGTQKIEEELKYIFPDIKTLRMDKDTTSKKGAL
                     DEILNKFKDKEADVLIGTQMLSKGLDFENVTLVGILSADMILNFPDFKSFETTFQLIT
                     QVSGRAGRADKEGKVVLQTYDTEHYAIKHAIEYDYEGFYEDEIKIRKAFGYSPFNNML
                     SVVVSGEDERLVIKNIKNMHASLIYLLEKRGINDLGFILGPNPCSISKINQNYRWQIL
                     FKDENIEINLLKGIIKYICITKRDLIFDKNINVSIDINPNSVL"
     gene            21761..22201
                     /gene="def"
                     /locus_tag="KR231_000796"
     CDS             21761..22201
                     /gene="def"
                     /locus_tag="KR231_000796"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HBH0003202.1"
                     /translation="MALRQIVQIGEPVLRKKSKKVEKIDEKIIQLLDDMAETMYDADG
                     VGLAAPQVGILKRVVVIDIGEELIELINPEIIETSGEQIDEEGCLSVVGEAGNVRRPN
                     YVKVRALNRNGETIELEGEELLARAFCHEIDHLDGILFVDKIEK"
     gene            22216..23145
                     /locus_tag="KR231_000797"
     CDS             22216..23145
                     /locus_tag="KR231_000797"
                     /EC_number="2.1.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861609.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionyl-tRNA formyltransferase"
                     /protein_id="HBH0003203.1"
                     /translation="MKIVFMGTPDIAVPCLQKIIDEKYEILGVVTQPDKPKGRGKKLG
                     MSPVKELAIENNIPVYQPVKARDKEFIDKIKSLNPDVIVVVAFGQILPKEILEIPKLG
                     CINVHVSLLPKYRGAAPINWVIINGEEKTGVTTMYMDEGLDTGDMILKTEVNLDENIT
                     AGELHDKMMNIGAETLKETLRLIEEGNAPREVQNHEEFSYAPIMNKSLGNIDFSKSAR
                     EIHNLVRGVNPWPSAYTTYNDVIMKVWKTKVLDEKSTKDVGTIIDVSKDGIKVSTIDN
                     VLLIEEIQMPNKKRMLVGEYIKGNTIETGLVLG"
     gene            23155..23907
                     /locus_tag="KR231_000798"
     CDS             23155..23907
                     /locus_tag="KR231_000798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF116 domain-containing protein"
                     /protein_id="HBH0003204.1"
                     /translation="MTDIKKYLTSVGILILILGILIGVVNFFIISLTQIFSLMINIII
                     ISLILIILCSTVVTYRVIKGKYVNSNIMKINFNIVSGLFPIISFIASSFGMSKSDIRR
                     IYIKLNNEYIYSNKYNFNPEDIIILIPHCIQENSCKLKVTNDIDNCKECGRCNIGELI
                     KLKEKTNVKIFVATGGTLARKIIMDTKPKAVVAVACERDLTSGIQDIKKIPVLGVFNK
                     RPNGPCVNTNVDMMDIEKAIGFLTGKNILVCN"
     gene            23976..24677
                     /locus_tag="KR231_000799"
     CDS             23976..24677
                     /locus_tag="KR231_000799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc metallopeptidase"
                     /protein_id="HBH0003205.1"
                     /translation="MYPVYGGFWGFDPTMVVLIPAILLTIYAQFKVSSTTNKYLRVNT
                     RRGYTGEQTARRVLDSNGLYDVKIEMVRGHLSDHYDPRRKAVRLSEDVYYGTSITSVA
                     VAAHECGHAIQHAKGYAPLQIRSSLVPVVNFASSISWFLIFLGFIMAGPFLKIGILLF
                     SASVLFQIITLPVEFNASSRAIVQLGNLGIIDESESRQSRRVLSAAALTYVAAALVSI
                     LQLLRLLLIAQRRND"
     gene            24739..26064
                     /gene="rsmB"
                     /locus_tag="KR231_000800"
     CDS             24739..26064
                     /gene="rsmB"
                     /locus_tag="KR231_000800"
                     /EC_number="2.1.1.176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(967)-C(5))-methyltransferase
                     RsmB"
                     /protein_id="HBH0003206.1"
                     /translation="MDAREVGFKVLCDIEKNDNYSNIAINKHFKNLEISDMDRGLATE
                     LIYGVIENKYYLDYIINKLSKIKVKKMSTYVKIFLRMGTYQILFLDSISDYAAVNETV
                     KLSKKYDKKSSGFINAILRNEIRAKETIMDITEEDSVKYLSIKYSYNSWIIKNWIDKF
                     GQEFAEDLLEANNEKPSIYIRTNTLKISREELIEKLSEMGIVCLKVPMVEEAIKVEKM
                     KNIEKNELFKAGLFTIQDISSMIVGKVINPKEGSFVLDVCSAPGGKSTHLATLMNNTG
                     QVVARDIFEHKLKLINSTVNRLGLKNVFVERFDASEIDENSISKFDYVLADVPCSGFG
                     IIRRKPEIKYKKEEELKDITSIQKKILENASKYVKVGGTLVYSTCTIQDVENINIVTS
                     FVEENHNFEFVPIDTVNVDLDNQDKGYLKIYPNIHGIDGFFIAKLKRIR"
     gene            26072..27103
                     /gene="rlmN"
                     /locus_tag="KR231_000801"
     CDS             26072..27103
                     /gene="rlmN"
                     /locus_tag="KR231_000801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2503)-C(2))-methyltransferase
                     RlmN"
                     /protein_id="HBH0003207.1"
                     /translation="MEKKKIVLKNFTEDELKEFMKTIDEKPFRGSQIFSWIYKGAKTF
                     DDMNNIPKSLRNKLEEVSCIGHIDIELKLESKVDNTKKYLFLLDDGNIIETVMMDYDS
                     RVTVCVSNQVGCRMGCNFCASTMDGLIRNLEPWEILDQVIKIQEDTGKRVSNLVLMGS
                     GEPLDNFENTKQFLKIINEKNGLNIGYRHITLSTCGIVPKMYELADLEIAINLALSLH
                     SPYDEERRKIMPVANAYSIEEILNACRYYIKKTNRRVTFEYSLIKGVNDSEKEAKALA
                     KLLKGMLCHVNLIPINKVEEREYEKPDKAFIYKFRDSLEKNNIPATVRMSMGSDISGA
                     CGQLRRKYK"
     gene            27123..27875
                     /locus_tag="KR231_000802"
     CDS             27123..27875
                     /locus_tag="KR231_000802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Stp1/IreP family PP2C-type Ser/Thr phosphatase"
                     /protein_id="HBH0003208.1"
                     /translation="MVYSCASHIGKIRKNNEDYCEGEVIDTEHGPIGIFAIADGMGGH
                     KKGEVASKLAVENIIDFLKENLLQHDNVKIDYIDDILKQAYNNVNSIVHKKSMEDIEF
                     EGMGTTLVTAIVYNNVLYVANVGDSRCYLLTDEKFDKITIDHSVVEELMMAHVITEEE
                     ARRHPQRNRITRAIGTDDMVVVDIFKKEIKKSDIILLATDGLTGFIDDEDIRDLILDY
                     EYERTSNISEELISMANDVSGKDNVSVIVIKV"
     gene            27892..29907
                     /gene="pknB"
                     /locus_tag="KR231_000803"
     CDS             27892..29907
                     /gene="pknB"
                     /locus_tag="KR231_000803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Stk1 family PASTA domain-containing Ser/Thr
                     kinase"
                     /protein_id="HBH0003209.1"
                     /translation="MGDTILGNRYEIIRKIGDGGMAFVYEAKDRLLNRTVALKVLRPE
                     FVDDDEFLTKFKREAEAVASLSHPNIVNVYDVGEDGKVHYIVMEFVDGKNLKEIIQDE
                     GILDEYTALDITKQIAMALSAAHKKGIIHRDIKPHNILISNEGRVVKVADFGIAKAVS
                     NSTMTNIGSIIGSVHYFSPEQAKGKFVTNNADLYSLGIVLYEMLIGKVPFRGDSPISI
                     ALQHINDDIDFTSEEKVRIPQSVRTTIKKLTEKSSADRYQTAEELIEDIEYIEKNIDL
                     DFIKEYDDFATKKIDEKEINKVVNPTLAKPAPEKVVKPVEVADLDDDEDYYDDFYEED
                     DDEDEEEEEIMRAKKNQRPKSTPSKRTKKKKKKQESPKSRRRLKVIAAVLILILCAQV
                     FLAYKFLFAGGFGNKSLTVPNLVNMTLEEAQSAVEKEGLYLSVKSEEYNSEVDENCII
                     SQTPEGGSTNVKKGDTINVVVSKGSSQASVPNVVGLTLSNAKQLIEENNLKVGTVKYE
                     YSSIYKEGTVLSQSPGAGSSRAQEGDEVNLYVSKGSEKSNTQTPTVPDKKPTTPENNT
                     PTEPGSNSGNSGGNSGGSNSGNSGGNSGNNGSNSGGSNSGNSGGNSGGSNSGDNGGSS
                     GGSNSGDNGGSSGGSNSGDNGDSSGGSNSGDNGGTSSGTGANIGKTE"
     gene            30015..30752
                     /locus_tag="KR231_000804"
     CDS             30015..30752
                     /locus_tag="KR231_000804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HBH0003210.1"
                     /translation="MKKKTVLITGGARGIGKAMSKAFAKEGYNVLVNFNKSENEAKEL
                     YTILNEKNFSVKLFKANISNREDVEDMVDYCIKEFGGLDVLVNNAGVSQDKLFTDITD
                     EDWDNMMNINLKGSFYCSQVALKYMISEKKGNIINISSIWGISGASCEVHYSITKAGI
                     IGMTKALAKEVGPSNIRVNSIAPGVINTDMLSGYNEEDIDALVEETPLMRLGTPEDIA
                     NCAIFLASDKSNFITGQVISPNGGFVI"
     gene            30850..31734
                     /gene="rsgA"
                     /locus_tag="KR231_000805"
     CDS             30850..31734
                     /gene="rsgA"
                     /locus_tag="KR231_000805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome small subunit-dependent GTPase A"
                     /protein_id="HBH0003211.1"
                     /translation="MLEGKIIKGISGFYYVDTYNGIYECKARGIFRKQKITPLVGDRV
                     KISIVDEDEKKGILEEIDSRDTELIRPPIANVDKALIVFAIKNPKPNLSLLDRFIVLA
                     EKENLETVIILTKADLDDNDTLETVKNIYELSGYKVIPVSNITKLNIDKVKEELKENV
                     VVFAGPSGVGKSSLLNEIDENFKLQTGVVSDKIKRGKHTTRHAELLKLEFGGMVADTP
                     GFSSLALEDIEEVELKDYFIEFDKFNDCKFGSKCIHENEPNCAIKEAVTNGEISKERY
                     DSYIQLLHEIRQNNSRRY"
     gene            31739..32410
                     /locus_tag="KR231_000806"
     CDS             31739..32410
                     /locus_tag="KR231_000806"
                     /EC_number="5.1.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribulose-phosphate 3-epimerase"
                     /protein_id="HBH0003212.1"
                     /translation="MIKLAPSILSADFAKLLEDVRKVESAGCEYLHIDVMDGHFVPNI
                     TLGPLVVKSLKKENINMVFDAHLMIENPDQYIEEFVKAGCDIITVHQEACVHLHRTIQ
                     NIKSHGIKAGVVLNPATPVDTIKHVLSDLDMVLLMSVNPGFGGQSFIPCVLDKIKELK
                     AIIDSQGLNIDIEVDGGISPKNVAEVVQAGANVIVAGSAIFGSDDIQETVNLFRKNAS
                     LEELV"
     gene            32419..33060
                     /locus_tag="KR231_000807"
     CDS             32419..33060
                     /locus_tag="KR231_000807"
                     /EC_number="2.7.6.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416274.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine diphosphokinase"
                     /protein_id="HBH0003213.1"
                     /translation="MKICIVLNGEIEDYEVTRDIIIKECYDCIICADGGANHTYKMEI
                     MPDYILGDLDSVEEEKINFYKNKGVKFEKFPSKKDETDTELCLFLAKTLKANHIDFFG
                     ALGGRIDHTLANIKLLYYLKEDGIYSRILSDKEEMYIVENEEISLYGNPGDTISVIAI
                     NGDAKGVTLTGLEYPLDNYYMKYSVPIGISNVMLSNSCKIKVEQGCVLVVRNL"
     gene            33191..33820
                     /locus_tag="KR231_000808"
     CDS             33191..33820
                     /locus_tag="KR231_000808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HBH0003214.1"
                     /translation="MVDSIIFDLDGTLWDSTEEVCKVWQDVLSEHKEIELSVTKDLFR
                     SLMGLSFEEIANRLFPNLSEEERMNLLNECSLKECDYLSENGAKLFDDIEDTLKLLSK
                     KYKLFIVSNCQAGYIESFLKAHKLEQYFIDFECPGNTGLHKGENNKLIIERNKLINPI
                     YVGDTQGDANSAKFVGIPFIYAKYGFGNVDVYDYFIDSFKDLLEHDILK"
     gene            33875..34531
                     /locus_tag="KR231_000809"
     CDS             33875..34531
                     /locus_tag="KR231_000809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HBH0003215.1"
                     /translation="MELQDTIFKRQSVRKFKNQDVSDEDILKMIKAAGAAPSGKNIQN
                     WHFVVIKRRDLMEKIADVITKKQQEILVEMDKVSVDKANRFRKFVKNFTLFYLKAPVL
                     VLVFTKVYNPSGYYELELIDAPKETIDKLFIRNPGMQSLGAAIENFTLSAIELGYGSC
                     WLTSQNYAADEIEAVLEAETGFEKGEYFLGAMLALGVPEDNLKSPSKKPVEEICTFIK
                     "
     gene            34935..35651
                     /locus_tag="KR231_000810"
     CDS             34935..35651
                     /locus_tag="KR231_000810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBH0003216.1"
                     /translation="MNSYNILVVEDEKEIADAIEIYLLNQGYNVFKGYNGLEGLKVIE
                     NQEIHLAIVDIMMPKMDGITLTMKLRENYNFPVIMLSAKSEEVDKIMGLNIGADDYVT
                     KPFKPLELLARVNSQLRRYTKYLNMVGNKEQKVESDDSVFAIGGLELNENTKEVSIDG
                     KYIKTTPIEFKILSLLMRNAGRVFSADEIYERVWNENAVNTDTVMVHVRNIREKIEID
                     PKNPKYLKVVWGVGYKIEKI"
     gene            35626..37959
                     /locus_tag="KR231_000811"
     CDS             35626..37959
                     /locus_tag="KR231_000811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HBH0003217.1"
                     /translation="MDTKLKKFKDKYIVTIIVFILMLSASLGMISQYSTIQASAKGGA
                     ENPFEQESFVDSIYKGSYVLYHNMKEEQEGKMIQPSKLFINEETMNYIKNVSKEKDTY
                     DGSETYYTDDSINADFNENFENWEHFIKASGKNLKYYLVDKESNFEFFNDNKELGVLD
                     TTKNDASKENSNENQSKNTEMNDEERQKQITDIKENYRFYVVMNFDKDGKVNIVDSYG
                     VNQKIINQMLLSKAREDLMDTSLGGNSISYKLSPIKNITLVYAVPKVISKGDSVEYGY
                     GNTYFDDGIISYISNVENNSYYKISGMILKIILAIVVIVALAFPYRKSKELLGFDTLS
                     RIPLEILFIALAIIQGLVDLYPTVIISNTLSGNYVEYLINNDISAKMASILVSLMNLT
                     YWFVIFSIIFVFIILLKHILNVGIREYFTKHTVTGMFFVWLKKAGKAVINQIRTINLK
                     EKPNKTIVTILGINLLIIVIMCSMWFFGIILALIYSVVLFKILSDYSKKTIYEYNQLL
                     DVTKKISDGNLDVNMEKDLGFFNPIKDELGNIQTGFKKAVDEEVKSQKMKTELISNVS
                     HDLKTPLTSIITYIDLLKDESITDENRKLYIDTLDRKSQRLQHLIEDLFEVSKANSGD
                     VYLNIVNVDIVSLMKQTLLELDDKLADSSLIVKNNFSNEKIILPLDSQRTFRVFENLI
                     INISKYAMPNSRVYIDILETDNKVNIMLKNMSASEIDFSVDDIMERFVRGDKSRNTEG
                     SGLGLAIAKSFIELQGGKMNISVDGDLFKVTITFNKN"
     gene            complement(38276..40954)
                     /gene="mngB"
                     /locus_tag="KR231_000812"
     CDS             complement(38276..40954)
                     /gene="mngB"
                     /locus_tag="KR231_000812"
                     /EC_number="3.2.1.170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannosylglycerate hydrolase"
                     /protein_id="HBH0003218.1"
                     /translation="MKKTKVHVVPHSHWDREWYFTTSRSKIYLMKDFQDILDILEEKE
                     DFKYFTMDAQASLLDDYLKWRPQDEYRIRDLVQRRRLVIGPWYTQTDQLVISGESIIR
                     NLYYGIDRCNEFGEPMRVGYVPDSFGQSAQMPQIYRGFGIDSSLFWRGVSDDMVDTTE
                     FIWKGSDGSKVLAVQIPFGYYYGGNIPEDDSDLKEYLKDIIGKLKVKASTNNVYFPNG
                     FDQAPIRKNLPDILKKANEIDNENEYEISDIENYIDSVRNERNEFTELKGEFLNAKHM
                     RIHKSIFSSRSDLKIMNNKLENYITNVLEPLLTLSYSLGNEYPHLVIKDIWKLMFENA
                     AHDSIGSCNSDTTNEDVYTRYKQARDLSINLLDLHMRLISTQIKNNNEEITLTVFNGF
                     PEVRNEVVEFDTYIPGQDFVIKNKNGKILNYIIKEKEDITNYILTQTIRLNPSKKIYI
                     PKTVYRAKIALSVKDIPPMGYTQLVFELDTKNKCEIETSNCKEIENKYYKITANKNGS
                     LEILDKESNKTYKNQAVIEDNGDDGDSYNYSPPRKDIYVSSLDSVSSVEVLKSNIQEE
                     MILKYSLTIPTSLEERAIGKVSVKMPVTMKITLEPKEQIIKFNVNIKNNQALSHRVRV
                     LFNTEIASKFSIADQQFGIIQRPTVLEKDLALWKRDNYSWQEKPITIEPMQSFVTLED
                     GQRGIALITGCVREYQIVGDNLDTIALTLFRSFGYMGRENLLYRPGRASGEKIIATPD
                     AQLLKELNFDFGLYIYNNKFDEANVANTAKRFLTPIQIYEYADFLNGRLIFAFNDEKQ
                     IYENEFSLMNVNNSNFTVSAIKKEEKGDGIVVRIFNGMKNEDAKGSLNINKNVNDAYS
                     AMLDEIYDNTSKLKVNTKTVEVNSLSHCKVQTIVIK"
     gene            complement(41029..42135)
                     /locus_tag="KR231_000813"
     CDS             complement(41029..42135)
                     /locus_tag="KR231_000813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIC"
                     /protein_id="HBH0003219.1"
                     /translation="MSKKNKSLLSELKGHLMTGISYMLPLVIGSSLVVAIPKLTALAM
                     GITSLDAYKNVSGFYHILYLMEQVGWTGIGLLNTVLAGFIAFSIGEKPAMGAGFIGGL
                     IASNTNAGFLGAVIAGFFAGYVCKFLKKKIKISGSASGMMPLIIMPLITVGLTGFLMS
                     VVLAGPLGNINTSLNAWVAEMCQNGTNSVVLALILGAMIGFDLGGPVNKAAWMAGNAL
                     LLEGIYLPAILVNCAIVIPPLGYGLATFIRKSKFSNALAETGKGNIVMGIIGITEGAI
                     PFTLTNPLKLVPVNMIGCALGVGLSALLGVHAIMPPVGGLYGFISIGSGWAYLVGAIF
                     GALVIAILSTTLVDFNEDETTENTEFDEIELDIM"
     gene            complement(42249..42557)
                     /locus_tag="KR231_000814"
     CDS             complement(42249..42557)
                     /locus_tag="KR231_000814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIB"
                     /protein_id="HBH0003220.1"
                     /translation="MKIVAITSCIAGLAHTPMAAKALEQAASKMGHEIKVEQQGAMGR
                     VNTITKEEAQDADFILIASDQTISGMERFDGKKVIKVKIGIALKKPEAVLTKCIEAIS
                     "
     gene            complement(42560..43012)
                     /locus_tag="KR231_000815"
     CDS             complement(42560..43012)
                     /locus_tag="KR231_000815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBH0003221.1"
                     /translation="MVLQEKYIFIDKDLKSKEEVLNFIADSAYILGITTNKEALLKDL
                     LKRENEFPTGIKDGFAIPHTKSVNVKEASILYIKTTNELEWKTLDDSKVRYVFSLLAP
                     HKNEGNIHLKTLSKLATCLMEDDFTNEVKNASDASHLVKYITNKMKEE"
     gene            43246..45174
                     /locus_tag="KR231_000816"
     CDS             43246..45174
                     /locus_tag="KR231_000816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HBH0003222.1"
                     /translation="MHKRLLTLFKLLNESDDKITCKTLSNHLKVSERTIRNDITSING
                     TLEKNGAIIKIKKGEGYYIDILNLALYQQYLALISDDIMDSSEIPDSPIERNQYILKY
                     ILYNNTYIKLEDLANSLYVSKFTILNDIKRIKPILSKYNLILVSKPYYGVKVEGKEID
                     IRRCISNNMINRNFENYIIGITDREIELFNNVDLIELQRVVLSEINKFNINFLDFNLK
                     NFIIHLAITVSRILDGYCLDNVLDVVLTDFQSNTTVENIFNYIESKYTIIISKADRVY
                     LYNHFITKSSLLDNVSNRVDTKIIEYVEEILEVINNQYTFDLRNDSVLFDDLVLHFKS
                     ILNSKSYNLNKVNPLINTIKSNYPLAFEITLNAIEKVFKNSIYSLTEDEIGYVSLHIG
                     AGIERFFQSNIKCKNVVLVCGSGYGSSRLLEVQLNKVFHDKINILQCLSFNQFLASEL
                     SDVDIIISTIPLNHDSIPIVLVDLKLLKKDIENISKSITNNSHIYSNLLDNFFDKNLF
                     IVNPKIKDKDELIKLMCNKLTQSEIVFPSFAESVFYRESLSSTNIDDFLAIPHPMELS
                     SIRTKICISILDEPIYWSEDSTVKLIMMLAINKDDYIKINSIYDILLKIIHDNDIRDS
                     ISNCNDFDNFLSIIKSIV"
     gene            complement(45434..46195)
                     /locus_tag="KR231_000817"
     CDS             complement(45434..46195)
                     /locus_tag="KR231_000817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HBH0003223.1"
                     /translation="MEYTVQKLSKLAGISTRTLRYYDEIGLLKPLKINSSGYRIYGQN
                     EVNKLQQILFYRELGINLENIKNIINSPNFDSLSALKEHHNKLLAKRKQIDLLIENVT
                     KTIALKEGKYTMTDIEKFEGFKEKMIDENEKNYGTEIREKYGKDIIDTSNKKLKNMSK
                     QDYENWQNLNIEIISKLKKAFKTGDASSELAQEVAKLHHKWLSYTWNTYSKEAHSSLA
                     QMYVYDERFTSYYDREQPGLAKFLRDAIVIYTRDK"
     gene            46414..46890
                     /locus_tag="KR231_000818"
     CDS             46414..46890
                     /locus_tag="KR231_000818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rpn family recombination-promoting
                     nuclease/putative transposase"
                     /protein_id="HBH0003224.1"
                     /translation="MNLKRSNEKREEYRRMYSDKESFLSLIQNFTSVSIAKELTLKNI
                     ELETSFICEYKGKEVDIIYKVFSKSGKVSHYIVLEFQTEMDTEIVPRLKSYREQIWKS
                     FIMKKSLEEIEDKNFKLPKVIPVVLYSGPERLSRKKGILDIVESISEFSNNSSMKN"
     gene            46988..47140
                     /locus_tag="KR231_000819"
     CDS             46988..47140
                     /locus_tag="KR231_000819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-oxoglutarate translocator"
                     /protein_id="HBH0003225.1"
                     /translation="MRNNKSKVLLGILCLATGMAVILSMLLPGWIWSALTALILIGCG
                     ALLFFC"
     gene            complement(47300..47488)
                     /locus_tag="KR231_000820"
     CDS             complement(47300..47488)
                     /locus_tag="KR231_000820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L28"
                     /protein_id="HBH0003226.1"
                     /translation="MAKVCSVCGKGKVSGNQVSHSNKHNKRTWSANLRSVRAIIDGAP
                     KRVKVCTRCLRSGKIERA"
     gene            47849..48199
                     /locus_tag="KR231_000821"
     CDS             47849..48199
                     /locus_tag="KR231_000821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HBH0003227.1"
                     /translation="MSAKVTNQYGNIEIDNQVIAQVVYRAAMESYGLVGLAYKSKGIV
                     ELLKGENATKGVRVEEVEEDAIAIELYVIIQYGTNISTVANNIIDRVKYVVEKMTGVR
                     VTRIDINVQGIRVK"
     gene            48218..49861
                     /locus_tag="KR231_000822"
     CDS             48218..49861
                     /locus_tag="KR231_000822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DAK2 domain-containing protein"
                     /protein_id="HBH0003228.1"
                     /translation="MIQYIDGKRLREMFISGANNLQNNKELVDKLNVFPVPDGDTGTN
                     MSLTISYALKELAKVENDNISDIGKALSKGSLMGARGNSGVILSQIIRGIAKSIEGKS
                     KLSTEDLAKAFKNGSDTAYKAVIKPIEGTILTVVRESGEFAIKTAKKEKDVVKFLSML
                     VKESNSSLERTPDLLKNLKEAGVVDSGGKGLVLIYEGMLASIKGDNIEIKNVDLDTNI
                     STSMDFAKSTTSTDDIKYCYCTEFILESSKVEDTKIRDIMMAYGDSLAVVGDDGVIKV
                     HVHTNDPGNVLQEALKYGQLLTIKIENMKLQHENTLLDVEEKKENDSEPLEEEKEFGF
                     IATSMGEGLANIFKDFGVDHIIEGGQTMNPSTEDFMNAIKHINAKNIFIFPNNSNIIM
                     AANQAKELSDKNIIVIPTKNTPQGFAALVTFNGELSEDENKEAMMNALNSVKSGQVTF
                     AVRDTVMNEIDVKEGNIIGIAEGNLLSAGDYVDEVTSNLIEKLVDEDTAIITLFFGED
                     VTESQANELRTSLEEKFEDVDVELYYGGQPLYYYLISVE"
     gene            49942..51999
                     /gene="recG"
                     /locus_tag="KR231_000823"
     CDS             49942..51999
                     /gene="recG"
                     /locus_tag="KR231_000823"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase RecG"
                     /protein_id="HBH0003229.1"
                     /translation="MDLYKDVQYVKGIGPKKADKLNKLGIFTLKDLLYYFPRQFEDRN
                     NLKKIAQLEDGEKVTIKAVISSINTFSPKEGMTLTKIDVKDETGSAKVVFFNKSYIKN
                     TFRPGDSILVFGKVKKKFNNLELTSCELEYLTNSPKNTCRFMPVYQLTYGVTNKEIMS
                     IIRTVLEDKELIIQEYMPQRIIEKYRLCSIDFAVRNIHSPSSKESLKIALYRIVFEEL
                     LILQLGLFVFKSGRNKEDGIKFETSKDLKKIISALPFKLTKAQNRALDEIIQDMNLEK
                     IMNRLVQGDVGSGKTVVALLALANCVLNGYQGALMAPTEILAGQHYISLTESLKDFGI
                     NVGLLIGSLTKKQKDTVLEQIKNNEIDILIGTHALIEDKVEFNNIGLVITDEQHRFGV
                     MQRSKLSLKGANPDILVMTATPIPRTLALILYGDLDISIIDELPPGRQPIETIAIEKS
                     KRDRAYNNLVRREVESGRQVYIVCPLVEESEAIEAKSAVELVEELRAEYFHDLRLGLL
                     HGKMKSSEKDEVMRLFKDKEIDILVSTTVIEVGVNVPNATLMIIENAERFGLAQLHQL
                     RGRVGRGSHKSYCVLIYDSKTDVCRQRMAIMEETNDGFKISEKDLEIRGPGEFFGTRQ
                     HGLPELKVANLFKHIKILKLAQQEARYILGEDNNLQLKENMALKKEIIDKFKDTLKEI
                     SLN"
     gene            52058..52612
                     /gene="rsmD"
                     /locus_tag="KR231_000824"
     CDS             52058..52612
                     /gene="rsmD"
                     /locus_tag="KR231_000824"
                     /EC_number="2.1.1.171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(966)-N(2))-methyltransferase
                     RsmD"
                     /protein_id="HBH0003230.1"
                     /translation="MRVISGKARGLKLNTPKNEDVRPTTDRVKESLFNMINSYIMESE
                     VLDLFAGTGSLGIECLSRGAKSCTFVDISKESIDIVKSNIKKARVESESIILNLDFKT
                     AIDKLKLQNSKFDIIFMDPPYYKNMFIEAIEKIDNSNLLNEDGIIVVEHDTNDLFPDK
                     ICKLEKTRDKKYGNTTLTFYKMEA"
     gene            52614..53111
                     /gene="coaD"
                     /locus_tag="KR231_000825"
     CDS             52614..53111
                     /gene="coaD"
                     /locus_tag="KR231_000825"
                     /EC_number="2.7.7.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pantetheine-phosphate adenylyltransferase"
                     /protein_id="HBH0003231.1"
                     /translation="MENKPRKAIFAGSFDPITNGHLDIICRASKLFDELQIGVLNNPN
                     KKGLFSFDERVKLIEKSTSHLNNIKVVTFDGLLINYCQENGIGALVRGVRSGADVDYE
                     LQMAHMNRELNPDIETIILPSCTKYSFISSSLIKEVLLFDADIKNLVPKIVLEELKKK
                     TSGGN"
     gene            53115..53639
                     /locus_tag="KR231_000826"
     CDS             53115..53639
                     /locus_tag="KR231_000826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0003232.1"
                     /translation="MKIDLEMIELFEQLEEIFRSASTIPFSHKCTVDKDEVLAIINDI
                     RTLIPEEVTQAVWINKERNKIISQAKQDATNIVEQAKKEAERIQQEYQDNIEELKKNS
                     EDVVKAYVESSEPVVQADQRAKDIVDRAERIANEIRIGSIEYAEDVLSSVEYNLREIL
                     EEVKRDKAELRPKK"
     gene            53983..55902
                     /locus_tag="KR231_000827"
     CDS             53983..55902
                     /locus_tag="KR231_000827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HBH0003233.1"
                     /translation="MKERAKKILDFIIKNNNVTSQELQEKFNVSKRTIYYDILAINEQ
                     LGKSGNIKNVKHKFIFEGNLCDARKIISTEEDKFLDSDYRKTFILNKILLGEKISIEK
                     LTNEMLLSKNTVVQTITDVKKYLQTMGLRLEYKGKYKIIGDEYVIRELFLIIVQENVL
                     EINSISEEVSSFDTKGHIKLTDYSLLNLTKFVEFLNKRIRDGKTLYSYKYLNEAKKIS
                     YFSNCKELLCEEANENEQAYICTYISSLPSLNSEVKEDVVEEYVDKLIDKFEVNTAIK
                     LESKHEFKKNILRHLHSSYNRIRFKFPIRNPMLDETKYKHESLYKIIKSIIENEEEFP
                     VFEGIREEEIGFIAAYFGGYLRGSRDNGLRRNKVLLVCPNGLMVSKSLEIQLYKYIPT
                     IEIVGIVSIKQLKEVNVYYDYIITTIDIQNVNNVIVVNPLLTSSDVQLLMNKLISVKE
                     NEKYFNLELIIQAIRKNGVINNEEALKADLLNIIHKIDEGEMYQPMLKELINAERVNI
                     IKNVRDWKEAIKIASKPLLEDNSIEELYIENMIKSVEKYGPYIVLADRFALPHASSKE
                     GVNKLAMSLLIVEDEVDLLGKPVNIFMVLAAVDNTTHIRALASLSEMMYEEENVKLII
                     NGDKSSIIELINKQN"
     gene            55915..56202
                     /locus_tag="KR231_000828"
     CDS             55915..56202
                     /locus_tag="KR231_000828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBH0003234.1"
                     /translation="MKILAVCGFGVGSSMVLKMTIQKALKQLGIECEVENTDINSARG
                     ADCDCIFTSQELLNELKGTCNVDVYPVKKYMDLAEVTEVVQTFLSDKNDKK"
     gene            56970..57083
                     /locus_tag="KR231_000829"
     CDS             56970..57083
                     /locus_tag="KR231_000829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013483530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HBH0003235.1"
                     /translation="MIMGRHLWNPSYFVATVLENTEEQIGKYINNQKKQVK"
     gene            57085..58203
                     /locus_tag="KR231_000830"
     CDS             57085..58203
                     /locus_tag="KR231_000830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HBH0003236.1"
                     /translation="MIVVEKAYKFRMYPNKKQQELINKTFGCCRFVYNKYLAKRIEVY
                     KNDKETFTYKQCSSDLTNLKKELKWLKEPDKFSLQNVLKDLDNAYKKFFKEKAGFPKF
                     KSKKINRFSYKTNFTNGNIMYCGQHIKLPKLGMVKIRDKQVPQGRILNAAISKEPSGR
                     YYVSLCCTDVDIEAFENTNNQIGLDLGIKEFCISSCGEFIENPKYLKKSLNKLAKLQR
                     ELSRKTIGSLNRNKARLKVARLQEHIANQRNDFLQKLSTKLIKENDIICIEDLQVKNM
                     IRNSKLSRLISDVSWSEFIRQLEYKANWYGRQIVKVGKFFASSQICNKCGYKNEEVKD
                     LNIREWICPSCNETHDRDINASINILKEGLRLITIQNK"
     gene            58354..59571
                     /locus_tag="KR231_000831"
     CDS             58354..59571
                     /locus_tag="KR231_000831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HBH0003237.1"
                     /translation="MLIGLIAAFGLVLQKKKASDVIKGSLLAAFGIIIMETGTGMLVS
                     SIAPINGAFQSISGGAVTKGLSDVTFTASYGGIIGLAMFAGLAIHLMIARFTPIKTIF
                     LTGHMLYWFPFIFVASGVEAGLNGGVLITFAAVLSALYWSIMPWLLRKYVFDVIGDDS
                     FTLGHPSGCLALISGFVAKLVGNKEKSTEDINIPQSLSFFREISISGGMAVFLMFIVV
                     GIVIPGAFKDSNEFIGTYAIKQGLSFGAGLIIMLHGVRMLINQIMPAFQGISEKVVPN
                     ALPAFDCPILFNYKPNAVLIGFLVAMLTSTAMILIYNYFNVFNLLLIPLVITSFFECG
                     AAAVIGESQGGIRGAIIGTAIAAIFMVVLVGISAVIYSGTIQNWILIFGGNDLSLFGI
                     ISRFIGSLFGGIL"
     gene            59574..60314
                     /locus_tag="KR231_000832"
     CDS             59574..60314
                     /locus_tag="KR231_000832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HBH0003238.1"
                     /translation="MKFKYIDEIRRLIDIIENEEKVNMEKAVQIFVEAIESKNAIFSF
                     GASHAGILTEELFYRAGGCVLINPVFAKSLMLDTAPITHTSKMERLEGYGTALADKTP
                     IKKGDVVIVHSVSGRNPVSIEFAMKAKENKAIVICITNLSYSKSVSSRHSSGKKLYEV
                     CDLVIDNHGQKGDACVEIDGLNQKVSPTSTVIATTVMNSIIAQATQELVNKGLKNPPI
                     FYSANIDGGDELNKKIFDEYKSVIHYEY"
     gene            60637..61947
                     /locus_tag="KR231_000833"
     CDS             60637..61947
                     /locus_tag="KR231_000833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter substrate-binding protein"
                     /protein_id="HBH0003239.1"
                     /translation="MKKENKMEGIKVGMLKKLCSLAMVAIMTTTLITGCSSGNGKDSK
                     KDGEKEKLVLWMPPVENNMKEVWDPILDKFEEKNNCEVDLQIIPWDNYSEKFATAISA
                     GEGPDVGYMYAEMYPQFIESGAVEDLTNYATKEDKEQSIYIKTSEMMGGMYGMPFQAA
                     NPGVLYYNKDILEKLGEKPPKTWEDFKRICKKATQDTDGDGKIDQWGLAQGWGAKTFG
                     NLNWNWYPYLWQAGGDIFNDDLKSVKFNDKSGLEAANFLKELQAYVPEDSLSKDSNEM
                     IESVFGPGKAAFTIMLSSAATSVFDESFPDLNWGFVTGLEDKKAATFGAVDHLSLMSS
                     AKNKELAYKLIQHMLSVESMTEFHKAIPRAPITKGEPYQGDERFKEMVENDKNVYRPL
                     VVGPHGVEIYEYLWKELQTMISGDKTPKQALDDAAKYSNDLLAQ"
     gene            62045..62962
                     /locus_tag="KR231_000834"
     CDS             62045..62962
                     /locus_tag="KR231_000834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HBH0003240.1"
                     /translation="MENLVREFEENSKRKKTKLNIKPYMYILPLGIILVAFYVIPIIM
                     SIYFSFTKYNIISPATFIGLENYKKLFTDETLKVSIINTIKFTVVVVPCQTILSLILA
                     VWITGKGNSKIASFAKGAIFIPVLSSMVLIGMVWRALLNGEGSIIYQVLGAFGIESSK
                     LLGDSKTALPTLMFISMWKNIGYFMVIYISAIMNLPKHCYEVAKVDGATKLQEFIKIT
                     VPLLKPTTIMVVFLGSIWSLQVFDLIYTVTGGGPGISTMSIVMHAFNLNFKNFNSGYA
                     MTVANVLFLLIAVVSILQNKLVRRDNSDF"
     gene            62978..63787
                     /locus_tag="KR231_000835"
     CDS             62978..63787
                     /locus_tag="KR231_000835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HBH0003241.1"
                     /translation="MKTARRLLSDGLLLFIACASLVPFIYMLIISLKITYNSYSLDIS
                     FSTVTLQNYIDIFTKKGFAQYFFNTAIVSFSGVLLNLVFSTLAGYSFAKMDFKGSDKL
                     FLFMIMTLIIPSQVTMIPLYIIMKHLGWINSYLALIMPIPTAFGVFIMRQAILGVPKE
                     LLESAKIDGCSDFRILIQIVLPLIKPALITLAIFTFMGAWNEFMWPLIATTKDTMRTL
                     TVGLSTLKTFQITNYGQMMAGATITFLPPFIFYLILQSKFVEGVSLSGIKG"
     gene            63845..65593
                     /locus_tag="KR231_000836"
     CDS             63845..65593
                     /locus_tag="KR231_000836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4091 domain-containing protein"
                     /protein_id="HBH0003242.1"
                     /translation="MEISYVLKDCTFKHNKYSVVEAETWKDKDLDIVVAKGEKFAFQI
                     MLKATEEFNCTIDKSSAISWKGLGNRVRLALNMPNSLENNFSINILGYVQDDTKAFVN
                     DAILRDKDVLVEQYLPQTFWIEGQVPEDFEENNLDIGIDIFKSFGYEDEEKVCTIDVP
                     VKVRNVVLKPLDESKFFLDLWQHPSCLARMYKVELWSDIHFEIVDNYLKELASLGEKV
                     ATVIVSDYPWAGQSCYKVYKNPSNLYEYNMVSVSKGLDGKIKCNFESMDRYISIADKY
                     KMAKEIDLFGLLGNWCAGEFGNPVEGYKDPIRVRYFDEKDKVFKFINNTNDLKEYIGL
                     VLNHLIECGLWDRVRIIADEPNNPEVVKECIEFINSTVSTHQVKYKSATHDQNFLDRA
                     KDEIDDMSINLKLTIQNYKDIESLKKKINDKGGILTWFVCCFPEKPNSFLSSPFVENR
                     IIGWYTYYFGLDGFLRWDYNLWTEDPWKDSSYKFPIWKAGDMFFVYPGKDLKPVRSVR
                     MENLRFGIQDFELFTMLEKEKGREYIEVELMQELLNKKENAEIKGFGDIELGYSLDNW
                     GYDKVKKYVLELLDRV"
     gene            65855..66877
                     /locus_tag="KR231_000837"
     CDS             65855..66877
                     /locus_tag="KR231_000837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 5 protein"
                     /protein_id="HBH0003243.1"
                     /translation="MFGGINIKRIGIIIMFFLSISFIGFYLVIRDNSDTVKMQRGINI
                     GNALESPKDFPWDVKMSNKFFDDIKDAGFDTVRIPVRFSDYTSDSDNFKIDEEFFKKI
                     DKYVDYALDKDLIVVLDLHHFEEIMKEPRVHKEKFLKIWQQIANRYQKYDKKLVFELL
                     NEPKENLYSQLLNEYIEEAIKIIRKTNPKRTIIVGPYNFYQIDYLNELNIPKDSNIVV
                     SFHYYEPNDFAFQGNIYHKGFEHLSNITWEGTNEQMDYLKKRFDTVENWANKNKVKIF
                     LGEFGITKEAPEASRRAWIKAVREEAEKRNFSWAYWELASGFGIYNQIEGTWDRDILS
                     ALIEKR"
     gene            66882..69188
                     /locus_tag="KR231_000838"
     CDS             66882..69188
                     /locus_tag="KR231_000838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HBH0003244.1"
                     /translation="MKKNSKKILITLTIITNVIYILWRIFYTVPKEEGKFALICAIIL
                     LFVEIMGMMEMFVHYYGMSNIEYPEKPIISEELYPHVDVFIATYNESVDLVRKTVNGC
                     IHMQYPDKKKVHIYICDDGNREEMCILAEKMGVNYITRTEREGAKAGNLNNAMQHTNS
                     PLIATFDADMIPMHDFLIATVPYFLKNEQAKKDGEKEEYEKVGFVQTPQSFYNPDLFQ
                     FNLHSEGRIPNEQDYFYRDIQLARNRTNSVIYGGSNTVISREALEEVDGFYTYSITED
                     FATGILIQSKGYRCYAIPEVHASGLSPTDLKSLIKQRERWARGCIQTGRRLNILFRRG
                     LGFWQKISYISSITYWYASIKRFVYIMAPILFSVFNVIVVKCTLLQVLVFWLPMYILS
                     SLSLKIFSQNIRNTRWTNIYETIMFQSLMPAVILETFAISKNKFSVTNKSKLEENRMY
                     KFLQGIPYFIYMVLSIIGILKMFVAIFKMSSMTYSVVLFWLIGNLFNLVMATLFISGR
                     QQLRKSERYIAEIDFKLKQNSYVLSSKTIDISENGFAFLLENPEYISPEEEFEVEFRE
                     KSGNEMYIANMKAKIVNVVEVNSKWKYAAYITHIEDSEIDNWMCIVHDRIPTLPMTIS
                     NQLGFFDDLQINVKKRIEKTRTLSRRSPRINMNFQMDIKNTGKLRIVNFNYQYVLLNF
                     ENKSIYPKEIALEINENIVLECDLCEGKIDERGILYKVNNIDSIMQNFFLRDEMMDWI
                     LQNKKILDSKPSEKKEKSIDEFEPMEYI"
     gene            69160..>69488
                     /locus_tag="KR231_000839"
     CDS             69160..>69488
                     /locus_tag="KR231_000839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0003245.1"
                     /translation="MSLNPWNIFRRDEMKTLKVFFCSTKYLILVFIFFINTTFISSAT
                     SDKILDLSFKKIETDLSSKITYEDTGVKIETDSSKSDKERYLYIYQNIKENWSMYNNF
                     YIEIQNK"
BASE COUNT        27147 a         7437 c        12176 g        22728 t
ORIGIN      
        1 ctatataata aatatataac agagagatga taatgtgtgt ttaacacaat taaatcaaat
       61 gagatatttg aacaaagaat agtataaaat ttttaaagaa atatgttgta tgagtaagaa
      121 tctacataat attgtattat atgatattcg aaagtattat ttctaagaaa agagatttct
      181 aaagtataaa attaaatact agaattgtaa agttaataat aactacaagt tattacaagc
      241 ttatgctagc tagtattagt tgttaataga agtacaacta tttcttattt aattaaaaga
      301 ttaaatgtgg aaagttttgt gataggatta cttcaaatat gtaatttata acaaccataa
      361 taaatttaga gtgtgtaaaa atttattttt taaagggaga ttatgaaaac atcaatttta
      421 atcgcattaa tagaaaagac aagccttatt gtagtattgt ttcttctaat aacaaagtta
      481 aaaatattta agcagatatt tcaaaaggaa gaatatagtt ttaatgactt ggtctgtata
      541 gcattagttt ttactttttt agccatattt ggaacttata gtggtataaa ttatatgggg
      601 tcaatagtaa acactagaat aatatctata gtatcaggtg gcattttatt tggtccgatg
      661 gtaggtatta cagcaggagt tttttcaggg attcatagat attttatgga tattgggggg
      721 ataacatctg ttccatgtct tttatcaagt atactagcag gtgtattatc aggatttcta
      781 tataagagga taccaaaaca acatagagta atgtatggaa tattggtagg catgatttct
      841 gaaagtttta ctatattact tatatactta atatcatatc cacattcttt agcaattcaa
      901 ataatcggtg gaatatattt acctttaata gttgggcaga ttggaatagg atttgttata
      961 tctatagtag aggggattga gaaagataaa aaagatatag aagcgagaaa taaagcagaa
     1021 ataaaagcac ttcaaagaca aattaatcca cattttttgt ttaattccct aaacacaata
     1081 gcttcattta taagatttag tccagataag gctagagagt taataataaa tttatcaact
     1141 tatctaagat ataatcttga atatagtgat aacttaattg atataaataa agagattgaa
     1201 caagttaaat cttttgtaga gatagaaaaa gctaggtttg gagaattact aactgtatct
     1261 tatgatatag aagatgtaaa tataaagatt ccaagtttga ttatacaacc attagtggaa
     1321 aatgcaataa tacatggtat tttagaaagt ggtagagctg gtgtagtgaa aatatccata
     1381 aaaaagttac cgtattcatt agaaaatact gtgagaatat caatagagga taatggtata
     1441 ggtataagtg aggaaattat aaataatgta tatcaagata atatgccaga aaataagatt
     1501 gggctttata atgtacattt aaggcttaaa ctgatgtatg gaagagggct taatataaga
     1561 agaatagata atgggacttt gatagtattt tatgtaaagg agtagaagta tgagagctat
     1621 aatagtggaa gatgaatttc cagcaagaaa ggaattgaga tattttattg aaaataaaag
     1681 tggaatcgag gtagtaagtg aatttaccaa tggtatagag gtgttagact ttattcagga
     1741 aaataaaata gatgtaattt ttttagatat aaatatacct catcttgatg gaatgctact
     1801 tgcaaaaaca ttaaatcagt ttaaatcaag acctaaaatt gtttttataa cagcatatga
     1861 aagttatgca gtagatgctt tttctttgga tgtatttgat tatatattga aaccatattc
     1921 tgaagagaga attatttcta tgctgaataa attagaaaaa agtgagatga gtgatattga
     1981 actatttaat gtaaatagta atttatacaa atataagaag gaagcagtaa atcaggagat
     2041 agaagaaata acacataaaa ttagcctttg gaaaggtgat aaattagttg taatagatat
     2101 tgatgatata tattactgtg aagctaatga aaggcagaca tttatatata ctgagaaaga
     2161 aaagtttata ttaaaagaag gcatatcaga agtcgaaaat cttataaatg ataaaacatt
     2221 ttttagaaca cataggtctt atatcgtaaa cttaaccaaa gtaaaagaaa ttataccatg
     2281 gtttaataat acatacatat taaaattaaa aaatagtgat tatgaagtaa ctgtaagtag
     2341 aagcaaagta aaagaattta ggctgttaat gcatatataa agtcatttca tgtacttaaa
     2401 tatgcactta atgtaattaa tatttatatt agcataaaaa agtattacta tttgaactgg
     2461 aaatagtttt cttaaactca taaaaattta taaagcaatt atataaaaac taaggggatg
     2521 aatttatggt aagcttttta ggttcaatag tagtacttat agtaggttat tttgtctatg
     2581 gtacttttgt agaaaaggtt tttggaacca atgacaaaaa tcaaactcca gctatagctt
     2641 gtagggatgg agtagattat gtgccaatga aatggaagag aatcttttta attcagtttc
     2701 taaatatagc agggttaggt ccgatatttg gagctataca aggagcatta tttggaccat
     2761 cagcattttt atggattgtg tttggaacaa tctttgctgg tggagtacac gattttgctt
     2821 caggatatct atcaatgaaa aacaaaggta catctgcatc agagttggta ggcctttatc
     2881 taggaaatgg tgcaaaaata gcaatgagaa tatttagtgt tattctttta gtattggttg
     2941 gagttgtatt tgtaacaggt ccagcaggat tattaaagac attgacaggt gtaaacgcac
     3001 aaatatgggt tggagtgata atactttatt atattatggc tactgtttta ccaatagata
     3061 aattgattgg taaaatatat cctttatttg gagcagcatt attaattatg gcagtaggtg
     3121 tagctggagg attaataata aaggggtata acataccaaa tataaattta caaaatatga
     3181 atccaaatgg aacaccttta ttcccatact tatttataac aatagcatgt ggagcaatat
     3241 caggttttca tgcaactcaa tcaccactta tggcgagatg tgttgagaaa gagagtgagg
     3301 caagaccagt attttatggg tcaatggttg cagaaggtat aatagcttta gtttgggcag
     3361 cagcagccat gtcatatttc catggcatac ctcaacttaa tgtgatattt aatgatggtg
     3421 gagcagcaac agtagtaaat acagtatctg ttggattaat ggggcctatt ggaggagctt
     3481 tagctatact tggagttgtg gcatgtccta taacttctgg agatacagca tttagaagtg
     3541 ctaggctgac aatagcagat gcaatgaatt ataatcaaga tgcagtcaaa aatagatttt
     3601 taatagcttt accattattc gcagttggtg ttgctcttac atttatagat tttaatataa
     3661 tttggagata tttctcttgg gcaaatcaaa cacttgcaat gataatgttg tggactggtt
     3721 ctgcatattt agtcaaagca aataaaaacc attatataac tacattacca gcacttttta
     3781 tgactgtagt aacatttagt tatataatgc aagcaaaaga aggatttaga ctaccagtta
     3841 atatatctaa tggaataggt gttattgtag caataattct tggtctttta ttctttaaaa
     3901 aagcaaaaca tattaaagaa caaaataatc ataaattggc aagttagtaa aataataact
     3961 ataaaaatta aaaaattgta tttaaattat gttcaaagaa gagactatct caaaatagag
     4021 ataagtctct tttttattgc tgaaaggata aaaatatatt tgatttcata taaaaaagag
     4081 ggttaaatga actaaaaatt tcattttgag acattccatt tttcgaatca aatcttattt
     4141 ttattgtatg tttaatttac ttttccacat actattttta tgatgtaaat attaaaatta
     4201 gaggtgttaa aaatggatac taaaaaatat aaagataaat tattgaaaga aagagaaaat
     4261 ttaactaatt tagtagagga tatgaaagat aatactttat ttggagatac aactaaacat
     4321 acaagtgaaa agtattcatc aggagaatta tctagttatg ataatcatat aggagacatg
     4381 ggaacagatt tatatatgca aaatatgcaa aacagtctaa taaatcatga agagggaaga
     4441 ttgtatcaaa tagacttagc attatctaaa atagagaatg gaacatatgg gatttgtgat
     4501 ttatgtcata atcaaataga tttagaaaga ttggatatat tgccagatac aagtttatgt
     4561 aatgattgtg caaagaaaga aaataattta ttaggtgatg caatgcaaaa ccctgatgta
     4621 gaagattcta acttttattc agaagaccta acaaatttaa ctgatttaaa taaaaatgga
     4681 atattgagag attaaaaaac tgacattata aaatatattg ctagaatgaa ttagaaaaga
     4741 ggtaatgaca tgaagaaaat aatatggggt atatgtatat gtttattatc tatagtaggt
     4801 gtatatacat ataatcataa tacacataat caagatagtt caaaagaagc atatagttta
     4861 aatgacaata taaaagacga ttatgaagat gtaataataa aaaaaggaaa tgaggatgaa
     4921 aaaattttag cattaacttt tgatgatggt ccagatgagg attttacacc acaagtactt
     4981 gatatattaa agaaaaatga tgtaaaagca actttttttg tagttggaga aaaagtagaa
     5041 tataacaaag aattattaaa aagacaatat gatgaggggc atgaaatagg gaatcataca
     5101 tttacacata taaatgttgc aaaaaatagt tatagtagtg ttgaaaaaga aataacagat
     5161 acgcaaaata ttataaaaag tgtaatagga gtagaaccaa agatatttag acctccatat
     5221 agagccatga gtaaaagtgt ctgtgatatt atagtttcta aaggcatgaa tataattctt
     5281 tggtcaaact tagaccctag agattggtct aaccctggag tagatgcaat tataaatact
     5341 atccttacaa aggtccaaaa tggtaatata atacttttac atgattataa cactaaaaga
     5401 aatgataaat cacaaactat acaagcttta gaagtagtaa ttcctaaatt aaaagagaga
     5461 ggatataaat tcgtaacagt atctgaactt atacaacatt tagataaaaa taagcaagtg
     5521 caaaagtaaa aatatttgtt tgaagattag tggtgattgt aagtttaaat tacagacatc
     5581 attaatcttt aatctataaa atacacaaaa aatattgatt agtatggtat ttttaaattt
     5641 tttatacata atgatatgat tttaaatatg tagaaatcta caatataaaa aaagtagtac
     5701 tattttaaat tttgttctag ctttattaag aaaatacaat tttaataaag ttgctcttta
     5761 gagcattttt tttgtataat aataatagtg tgcttcaaat aaaattggtt tttaaataat
     5821 ttataggggg aaaaatcatt gctatatata ttaataataa ttctactcat aggtttagac
     5881 caactgtcta aaatatgggt attgaataat ttggtggatg tatcaacaat accaataata
     5941 aataatgtat ttcatttaac ttatgtcgaa aatagaggtg cagcatttgg attattacaa
     6001 aataatcaat ggatatttat aattgttgca ttacttgcaa cagtatttgg actatactat
     6061 cttaatacaa ggaaagtaca tatatttgga aggttgggaa ttatattaat tatatctggt
     6121 gcattgggaa atctaattga tagagtacga ttaggttttg tagtagatta cttcgacttt
     6181 agaattatat gggaatatgt attcaatata gctgatgtat ttgtagttgt aggaactgtg
     6241 tttttatgta tatatgtttt attttttgaa agtaaaagta ggtgatataa tggatgaagt
     6301 aaaagagttt ttagtacttg aagaggaaga agaagttaga cttgatattt atctagcaga
     6361 acaattaggt gatatgtcaa gaagttatat acaaaaaatt ataaaagatg gaaaagtaaa
     6421 ggttaataat aaagtagaaa aagctagata tctggttaaa gaggaagata atattgttat
     6481 agagatacca gaacctaaag tattagaagt tttacctcaa gatattccaa tagatattgt
     6541 atatgaagat gatgatgtct taataataaa taaacctcag gatatggttg tccatcctgc
     6601 tcctggaaac tatgaaaata cgttagtaaa cgggatttta tatcattgta aagataagtt
     6661 gtcatcaata aatggcgtta ttagacctgg tatagttcat agaatagaca aagatacttc
     6721 tggtcttctt atgatagcta agaacaatta tgcacataat tttctagcag aacagttaaa
     6781 ggaacatact ataactaggg agtatgaatt tatatgctat ggtgtggtta aagaagataa
     6841 aataactgtt gataaaccta tagggagaaa tcctaaggat agattaaaaa tggctgtagt
     6901 aaaagatgga aaaaatgcaa tcactcactt tgaagttgta gaaagatttg ataagtttac
     6961 acatatgaga gctaggcttg aaactggtag aactcatcaa ataagagttc atgctttgtc
     7021 tataaatcac ccacttttag gtgattatgt atatggtcca aaagaaacta aatttaaatt
     7081 aaaaggacaa actttgcatg ctaagaagtt gggatttata catcctacta ctaaggaata
     7141 tatcgaattt aattcagaat tacctgagta ttttaaggaa gttattaaaa agataaaata
     7201 actatttgta taatacttat aaatcatttt ttgtttttat ataagtaaat aaatttagtg
     7261 aaatttaaat aaaatatctt atattaaagt attttgttta aaaaagcttg aaaaatttga
     7321 aatataaata tataatttga tttgatagat taaaaaatta tctttaaacg atacagagat
     7381 atcgtaagac aattgctaaa ttgcactgta tattttttat ataagagctt cttgtcttgt
     7441 gatgagaagt ttttttgttg tttaaattga aattttaaat aaaaataaat ttataaaaaa
     7501 ttaaaagaaa ggagtagatt tgtcaaatag atatattata tctttgacaa taattatgat
     7561 atggtagaaa aagctcaatt aatggatgaa aaggcaatag caagagcaat tactagaata
     7621 agtcatgaaa taattgaaag aaataaaggt gtagaaaatc tagttttagt tggaataaag
     7681 actagaggtg tgccaattgc aaatagaatt tctaagaaaa tagaacaaat agaaggaaca
     7741 aaagtagata caggagatat tgatataact ttgtatagag atgatttgga aaaaattcat
     7801 gttgaacctg tagttaaagg aacttattta gattttaatg taaatgataa gacagtagtt
     7861 ttagttgatg atgttttata cactggaaga actgtgagag cttcactaga tgctattata
     7921 gatataggaa gacctaaatc aatacaatta gcagtgctag tggacagagg gcatagagag
     7981 ttgcctataa gagcagatta tgtaggaaaa aatgtaccta cttctagaca tgaaattata
     8041 tctgtcagtt tattagaaat tgatggagaa gattcagtta caatcaaaga ataattattt
     8101 ttaagtatta tataaaagct tagcattgaa tagtcaggga ggaggataaa gcttacatag
     8161 attgcacaaa ataaatatta taattttatg gatgtgagtc ttaatgtagt ttttattctc
     8221 ctttatttga gtttttgatg tcgtaaaatg taaaataatg ataaattata taataagtat
     8281 atagaggtta aaaaatagaa tctagggaat gataattaat taaaagatat taattaaaca
     8341 gaggatttat ttatatataa taattttgga ggtttttatg aaaaaaacga taatgtcttt
     8401 acaacatcta ttagccatgt ttggagcgac agtattagtt cccattttga caggttttaa
     8461 tccgtcagtt gcaattttct gtgctggtgt tggtacattg atatttcatt tttgtacaga
     8521 aggaaaagta cctgcctttt taggttcaag ttttgcgttt ataccagtta tactagcagc
     8581 taaagaggca tatggtggag atttagcata tgctcaaggt ggtataatag tagcaggatt
     8641 aatttatatt ataatgtcga ttatagtaaa agtagttggt gtaaataaaa ttaaattata
     8701 ttttcctgca caagttacag gagctatgat agtagttata ggattaaatt tattgccaac
     8761 agcttttagt atggcttcag ccaattttgt gatagcattt ataactttag caatagcaat
     8821 tttaaccaat aagtttggta gaggatttat aaaacaatta ggaatattaa tagcagtttt
     8881 ttctgggtat ataatctgtt tgatattaag attagtagat ataactacta ttacagaagc
     8941 aagtttattt gcaataccta actttacagt tcctaagttc agtttaggag caatagtgat
     9001 tatatctcca gttgtattag ctgtatttat ggaacatata ggagatatga ctactaatgg
     9061 tgctgtagta ggtaaaaact ttatagaaaa tcccggatta aatagaacat tacttgggga
     9121 tggatttgcg actatagttg cagggtgttt aggaggacca gccaatacaa cttatggaga
     9181 aaatacagca gtacttgcta taactaaaaa ctatgaccct tcaatactta gacgtacagc
     9241 aatatttgct atattgcttg catgtgtagg caagtttggt ggatttcttc aaagtatacc
     9301 aggttcagtt atgggtggaa ttagtataat gctattttcg atgataactt atgtaggatt
     9361 aaaaactata agggacagtt cttgtgtaga aagtaaaata aatatattaa tcatagcagt
     9421 tatattatta ataggtcttg gaacaacata tttatctaat aaaggtattt ctgttggaat
     9481 ccctataaca agtacagtaa agataactgg tcttagttta gctgcaattg ttggaattgt
     9541 attaaacaga attttaaata atcaggactt taaagttgaa gaagaataaa tttaaagaat
     9601 aagttgtata ttgaataact aaaattagtt aattttctat agacatttgt aattaatgtt
     9661 gatataatga ttaaaaataa atgaaagaaa gggcaaggta actaggacaa tgagaatata
     9721 atctattttt tataatttaa agtattgtaa tttttgaaaa gcctattttg gtggctttat
     9781 ttgcaatgct taaattaagg agagtagatt atagtctata cgtttatttg ttatgcctat
     9841 ttatagaatc tctccttata tttaagtgtg ttaaggaggg attttttatg ttgttagtaa
     9901 aagtagagaa tttaaagaaa tattatgcag ataaattaat tttggatata gataaacttg
     9961 aaatattaga aaatgacaaa ataggtctag ttggttcaaa tggtcaagga aaaacaacat
    10021 tattaaaagc aatattggga gaaatagaaa ttgatgaagg atatacttac cttacagaaa
    10081 gctattctta tataagtcag agtgaaaata atattgaaac atgtagtcat agtaaggaga
    10141 agagtctttt aaatgctcca gataaatttg aagaacactt atcaggaggg gaaaaggtta
    10201 agttaaaaat agcagatgcg ctgagtaata agaaaaatat cataatagct gatgagccaa
    10261 cttcaaactt agataaaaaa agcattgggg ttttggaaga tatgtttaaa aggcatgagg
    10321 gagcattatt attaatatct catgatagac gttttctgga tgagttatgt acaactatat
    10381 tagaactaga agatggaaaa ctaaaagctt acaaaggcaa ttacactgat tatttaatgc
    10441 aaaaagatga agaagtaaaa agagctgatt ttgagtatca agaatatgtt aaagagaaaa
    10501 aaaggcttga aaaagctctt ttatataaaa aagctttaag tgatggcata agaaaaacac
    10561 caaaaagaat gggtaattca gaagctaggt tgcacaaaat gggtggtcag actaataaga
    10621 aaaagttgga ctcaaatgtg aaggctataa aaagcagaat tgataaactt gaggtaaaga
    10681 ataaacctaa agtttctaaa gaaatgaaca ttaagatgca agatggtatg gagataatta
    10741 gcaaaaatct agtagaggta aaagatatga ctctaaagtt agaaaataag ctcctgttag
    10801 ataatgtttc ctttaagata aaaagaggta aaaagatagc attgttaggt gataatgggt
    10861 gtggaaaaag tactctgata aaagaaatat tggctgataa aaatgacaat ataaaaataa
    10921 ataacaaggt aaaagtaggt tattttgacc aaaatcaaag tttattagat gaggaaaaga
    10981 gtgttctata caatactaaa gttaatagtt catttgatga atcttttata aggataaact
    11041 taagcctatt tgggtttaaa ggtgatgatg tctacaaaaa agtaaaagta cttagtggtg
    11101 gagaaaaggt aaaaatagca ctatgtaaaa taatattgga agataataat tttttagtat
    11161 ttgatgaacc aacaaattac ttagatataa aatctatgga agcactggaa aaggcactga
    11221 taaatactga taaaactatg cttatagtgt ctcatgatag agtatttgta tcacatattt
    11281 gtaactatat tatagagata aaagatgcta aaataaggga gtttgattgt aattatgacg
    11341 aatatacaat tagcagaaat aaaaaaactc ctagtagaga aaaccaaatc aaaaaagaaa
    11401 atcttctagt attagaaaat agacttacaa ctgttatatc tatgttatct atagaaaaag
    11461 ataatctaaa aaaagaattg tatgaatcag aatataatga attactaaaa caaatcaata
    11521 aattaaaaaa tagcttttag tgttaacttt ttaattacat ctatataaga agactgaaaa
    11581 tatttgttgg gaatataagt atagttatta aaacagaaaa gtattttgtt agaaaattaa
    11641 aagtaagcta attagaaagt ggccttattg tactttataa gaaggccact atttttattt
    11701 agaatgataa tgtgtagttg tctaacattt attttgtatt tagtgcagaa tttattcaga
    11761 tttaacctta agcttggcta ctgtttcttc ttcaggagta acataaatag tactgttagt
    11821 ttcataaata accatacctg gtttagaacc actaggtttt ttcacatttt ttctcttagt
    11881 atagtctaca ggcacctgag aagaaagttt tgacttacta aagaatgctg ctagcatagc
    11941 tccttcaaat acagtattat cagggacttc cttaccagca cactttatta ttacatgaga
    12001 accaggaata ttttttgtat gcatccataa gtcatcatta tcagcaagtc ttagtgtaag
    12061 atagtcattt tgcttattgt ttttaccaac caatatttta aatccatcag aagacacaaa
    12121 ttcatgaggt tttgtagatg ggatagtatc ctttttactg tttttctttt gagtcttgat
    12181 gtatccaact ttagcaagtt cttcttttat atcttgtaat tcagctaaat tttcacagtt
    12241 ttcaatactt aaaattatgt tttctaagta atctatttct tccttattta aggaaatttg
    12301 atgagatatc tcgactttag catgtttcat tttgttatac tttttaaagt atttttgagc
    12361 attttcagat ggtgtcaagt ttttatttaa ttctattgtt acatcattac aattttcatc
    12421 atagaagtta gcaacttcaa tactttccat acctttttct accatataaa tatatgaagt
    12481 aatcaattct ccttttatct tataaatgtc tgcattttcg gattctgata attcttcttc
    12541 ttgtttttta agtttattat aaagtctatc aagcttaaca gatatactct tctttaaatc
    12601 agatgaacgt tgattaattc tatctttaat atccttagtt ctatagaaat cttccagaat
    12661 acgagacata ctatccttat ttatatatga taaatcgcta aataatgtaa ggtttataca
    12721 actgaaatca actaccttat ccaccttttt atctataata atgcaaggag agtatttgtt
    12781 agaatttata tcattgaata aattacaaaa tactttgtgt aaagcatcaa attgttcatc
    12841 agatatatcc tttatgatag cattttgatt tacacctgct ctgtagcaaa tttctttagc
    12901 tataataggg cttataccta gaaatttaga atatatagac ttaaagatag gtccttccaa
    12961 ttcctctagg tttttaataa acaaatcctt agatatatca tcaagagggt tgagtttgtt
    13021 ttgttctggt ggcaatgaat aatcatgacc aggtaaaact tgacgaactc tacttatgct
    13081 aaaagggact ctttttatag aatctataat tttattttct tcaccatgag ttattattat
    13141 gttgctatgt cttcccataa tttcaatcat aatattttta actgtctttt cttttaattc
    13201 atctaaagat tcaacactta tttttattat tctttcaaaa cctatttgag aaatttctac
    13261 tatatttcca ccttgtatgt attttctaag taacatacaa aacataggcg cttttagagg
    13321 gttttctttt tgataattac ttgtaagata aactctagga tttgaggcac ttgcacttaa
    13381 aaccaatcta aaattttctt tattatttct tatattaaaa attacctcat catcttcagg
    13441 ttgatgtatc ttatctattt ttccacctgt aagttttgat gataattcat cgactattga
    13501 atgtataact aatccatcta atgccattta tagcacccct ttctttgacc aaaatgagtc
    13561 agtaaattaa ttatacacat aatatacgct ttgtgactag ggggaattta aacaatagag
    13621 attaatattt aaattgtata attatttata tttattagag aggaaacttt atttttaaaa
    13681 ttaataattt aaagtagatt aaatataaag taaatatagt ataattattg tgtagagtat
    13741 aagctatgaa agtatatgaa ctttacagaa aaaatcaatt ttaaggttct atagtatata
    13801 aatatgaaag aaggttgaaa aaatgagatt tatcgattta agaagtgata ctgttactat
    13861 gcctactgac gaaatgagag aagctatggc aaaggctcct gttggagatt caatctttag
    13921 agatgaccct actgtaaata aacttgaaga attagcagca gctaaagttg gaaaagaaga
    13981 tgctattttc cttccaagtg gaacttttgg gaatcaatta gctctattta ctcattgcct
    14041 aagagggcaa gaaataatta ttggtaaagg ttatcacatt gtgactcatg aggttggggc
    14101 acctgctgta atagctggag ttcagcttag aactatagat gaagacgaaa gtggagctct
    14161 aaatcctgaa cttgttgaaa aggcaattag aagagatgac atacatgaac cacagacagg
    14221 gcttatatgt gtagaaaatg catattcagg tggaacagtt gtgagtcttg ataatttaag
    14281 agaaattaaa aaaatagctg agaaacataa cttaccagta catttagatg gagcaagatt
    14341 atttaacgca gcattaactt tgggtgtaga agctaaagaa atagcaaagt gttgtgatag
    14401 tgttatgttc tgtgtgtcaa aaggtttagc tgcaccaatg ggttctatac ttgctggaaa
    14461 taaagaattt atagcaaaag ctagaagaaa gcaaaaagtt atgggtgggg gaatgagaca
    14521 agtaggtata gttgcagcag ctggtataat tgccattgaa aaaatgactt taagattgaa
    14581 tgaagaccat gaaaatgcaa aatatttagc ttgtgaatta aataaaattg atggcattga
    14641 agtaaacaat gttaatccag atataagtat ggtatttttt aagatgagtg aagatattat
    14701 aaaagaggat gttttaataa aagaattttt tgaaagaaat ataaaaatta ataaaatgga
    14761 aaatggtgaa tatagatttg taactcatgt agatattact aaggaagatt tagactatgt
    14821 tttaaaaaca cttaaagaat taataggtgt atgttaatag atatctacta gaaggattat
    14881 agctagttac cagatgttta attaaaaaat tcatagacag tttaaataaa acatacataa
    14941 aattcatata gaaatattaa tatataaaca tagaaagaac tagcttaaaa acataatata
    15001 attaccctaa ttgtaatggc aactctccct cacatcctca aattatagtt gtcattacaa
    15061 aacttttccc ataaattata agtttatggg aattttttta tgttataata gtttaagcgt
    15121 taatttacga aggagcgata cttatgaaat tttggaaact acatggaata ggaaatgatt
    15181 ttatagcaat agatggaaga ttcgaccaga taaatccatc tgattatact gctttagcaa
    15241 aaaaagtatg ccatagaaga ttttctgtag gagcggatgg attgttagtt gtgaaagatt
    15301 caaaagttgc agatgtagaa atggtatatt ataattctga tggttcaaga gcagctatgt
    15361 gtggaaatgg ccttagatgt ttttgtaaat ttgtttatga taattgtata gttaaaaaag
    15421 aaagttttac agtagataca ttagatggta taaaagatat aaaagtaaat cttactaata
    15481 gagaaataaa ctctataaga gtcaatatgg gaaaaggaag ttttatagct aaggacgttc
    15541 ctgtacttac aaataaagaa cgttttgtgc aagaaagtat aaaggtttta gatagggagc
    15601 ttaaagttac ttctatgttg atgggggttc ctcatacagt agttatagta gatgaattag
    15661 atgtagatga tgtttgtaaa tatggaaaag agattgaaaa taataaaata tttcctgaaa
    15721 aaacgaatgt aaattttgta aaggtagaag ataagtataa tatacatgtt tatacttggg
    15781 aaagaggttg tggatatact ttaggttgtg gtactggtat gactgcatca gcaatagtgt
    15841 gcaatttact taatatggta gaaagtagtg taaatgtaac gtctcaaggt ggaacagtta
    15901 aaatagatgt aggagatttc tcttatatga caggtccagc agtaaaaata tgtgaaggta
    15961 ttttggaggt ttaattaatg gctataagta tgactggttt tggaagagga gaatacaagg
    16021 atgataatta ttacttttta gtagagtgta aaacgataaa tcataagtat tcagatataa
    16081 acatacgtct tccaagaaaa atttcatttt tagaggataa agttagaaat ttagtaaaaa
    16141 attatgtaaa aagaggaaga gtagatttat acataaagtt tgacttatta ggcaaagaag
    16201 atgtaaactt aaattttgat gagggattag catctcagta tatagacata ctaaaagaaa
    16261 taaaaaataa atttgatatt atagatgata ttagcgttat gaatgttgca aagtttcctg
    16321 atattgtgaa aatagaagaa aaggaagaag atgaagattt attgtggtca atgttgaatc
    16381 aagcagttga agatgcatta atcaaattaa gagaaatgag aagtgaagaa ggtaaaaaat
    16441 tagctgaaga tattgccatg agatgtgatt tattaaaaaa tcatatagaa gagattgaaa
    16501 aatattcaag tagtgttgta gaagattata gagaaaaatt gaatttgaga ataagtgaat
    16561 tactggatga cccaagtata atagatgaga atagattagc acaagaagtt gcaatatatg
    16621 cagataaaag cagtataaca gaagaaatag ttagatttaa aagtcatata gggcaactta
    16681 aaaatactat atttaaagac gactctatag gtagaaaaat agatttctta atacaagaga
    16741 tgaatagaga aactaacact ataggttcga agtcatctga tataaatata actaatttag
    16801 tagtagaagt aaaaagcgaa ttggaaaaaa taagagaaca aatacaaaat atagagtaag
    16861 aatacaatat tagaagggga atgcttaaat gtttgtgaaa aaaggattat tgctagttgt
    16921 atcaggacca tcaggtgcag gaaaaggtac tatttgcaaa gaactactta aagaaaatga
    16981 tacaataaaa ctttctgtat cagctactac aagaaaaccc agaactggag aagttgatgg
    17041 agtaaattat ttcttcataa gtaaggaaaa gtttgaagag atgatagaaa aaggtgagtt
    17101 tttggagtat gctcaaattt atgataattt ttatggaact ccaaaagcgg caataatgga
    17161 atgtttagaa aaaggacaag atgtattact ggagattgaa atgcaaggag caaaacaaat
    17221 aaaagaagtt tgcccagagg gagtatttat atttgtacta ccaccatcac ttgaagaatt
    17281 aaaaaataga attgttggaa gaggtacaga aacagaagct gaaatagaga agagatttag
    17341 ctgtgcatat gaagaaatta aaatgattaa ggattatgat tattttatat ttaatgaaga
    17401 tgtaaaaaca tctgctaaag aaatagaagg tataatatca tctgaaaaga ataaagttag
    17461 cagatataaa aatattataa tagagaaatt taaggaggaa ttataattat gttaaaacca
    17521 tctatcaatg aggtactaga aaaaatagac aacagatact atttagtggg gactgtttca
    17581 aagagagcaa gaaaattaat tgatggagaa gaaccatatg tttcaaataa aactaaggaa
    17641 aagcctgtat gtgtagcaac taaagaagtt gcaagtggaa aaataacata tagattattg
    17701 acagaagagg aaatagagat agaagaagct agacatcatg ctgagcaaca ccaacaaatt
    17761 tcagaagagg agtaaggtca tgctaaaaga taaaactgtt gtaattggca taagtggcgg
    17821 tatagctgca tataaggctt gtgatgttgt aagtaagtta aaaaaactaa atgcaaatat
    17881 ccatgttata atgacaaaat cagcaacaga atttgttaaa ccacttacat ttcaatcgct
    17941 gagtcaaaat tatgtagtag aagatatgtt tgaagaacca aaaacttggg aagttgaaca
    18001 tatatcatta gcaaaaaaag cagatttatt cttaatagtg ccagcaagtg caaatgttat
    18061 aggcaagatt gcaaatggta tagctgacga tatgttgaca actactgtta tggcaacaaa
    18121 agcacaggtt cttatagcac cagctatgaa tactaatatg tatgaaaatc caattgttca
    18181 aaaaaatata caaactttaa agagctttgg atataaattt attgaaccgg aaagtggaag
    18241 gcttgcatgt ggagatattg gaacaggtaa actagctaat ccagatataa tagtagagga
    18301 agttttgact aatcttacta aagagcaaga tttaaaaggt caaagtatga tagttacagc
    18361 tggtccaact gtagagagta tagacccagt aagatattta actaataggt cttctggtaa
    18421 aatgggatat tctatagcaa gagaagctat agctagaggt gctgatgtaa cattaatatc
    18481 aggtcctaca aatctttcta ttccacaaaa tcttaaaaaa tttgttcaaa tagagtcagc
    18541 acaagatttg tatgaagcag tagtatcaaa tttaagtgaa aataaaatag taattcaaag
    18601 tgcagcagtt gcagattata aaccaaaaac ttattctgac aaaaaaatta aaaagaagaa
    18661 tgatgattta tcaatagaac taagtagaaa ttatgatatt gcttatgaaa taggaaaaat
    18721 aaaagaagat aagatactaa ttggatttgc agctgaaact aatgacctta tagaacatgc
    18781 caaaggaaaa ataaaaaaga aaaatttaga ttttattgtg gcaaatgatt taactaaaga
    18841 aggtgctggt tttagagctg atactaatat tgtaaaaata atagatgtag agggaaatat
    18901 tactgagtat cctaagatga aaaaagaaga agtagccaat gttattttag ataaagttaa
    18961 agcgttgctt gagaaataag acctttttta aatatgatat ttgtgtattt tatcacagct
    19021 aaagtggctg aaagctgcaa tttaatttta gcgagtaaaa actcgcaaat gtcagttaaa
    19081 ttgtagtttt cagcatttat tttgtcataa agtataaaat ataattaata gttaattatt
    19141 aaaataaagt taatattaat aacttgaaat tgcttataaa ttctgagatt ttaatatctt
    19201 gtaaagtata ttaaaatatg aacaatatat taaatttaag tagaggtttt ataatgaaaa
    19261 aatatgcaaa ggtaatagtt agaagtaata ctatatatac agataattta tttacatatc
    19321 aaattcctgt atttttatct gatgtaataa aaattgggca cagaatatta gtaccatttg
    19381 gaaaaggtaa taaaccaaca gaagcctttg tatttcaatt tacagatagc ttagatgaaa
    19441 aaataaaaat aaaagaaatt attgatatat tagatgaaaa tccgatattt agaaaagaag
    19501 atttagagtt ggtttattgg atgaaaaata gatatttgtg tacttatata gaatgtataa
    19561 atttgatata tccaaaggga tacaaattaa ataattataa agtagtccta ttaggtgaaa
    19621 gtttaagtgg attaaatgat attgaattga aggaaaaaat atcaacttta agtgataaaa
    19681 atagagaaat agtagagaaa gtgattgata gtaaaggtaa aattaaggtt gataagttaa
    19741 aatatatacc aaacttaaat agttctttgt acacaatgaa taaaaatgga attataaaat
    19801 tatgttggga atataaaaat cacaaaaatg aaaagaaagt atgttatata tctttgagtt
    19861 tagaaagtga taagattgac gattatatag agcaaaataa aataaatgtg ggaagtaaac
    19921 aaaaagagat attaagtttt cttaaaaata atgaaaatgt agagataaat gatttattgg
    19981 atttattaaa tgcttcaaaa caaagtataa attctctaag taagaaaaag ctaataaccc
    20041 tagaatttaa ggattattat agagagccaa aaagtattta caaatccgta ctaaaaagta
    20101 taaaattaaa caatgagcaa caagaagcag ttgatgagat aaagtcgaat atgtttgtag
    20161 atgataaaaa accatactta attcatggag taactggaag tggaaaaact gaagtttaca
    20221 tggaaataat agaatttgct ctaaatcaag gcttagacag tatattctta gtacctgaga
    20281 tagcattaac tcctcaaaca atagataggc taaagagtag gtttggagat ttagttggag
    20341 tgttccacag taaactatct gaaggagaaa aacatgacgt ttacaaagct gtcaaagcag
    20401 gtaaagtaag agtgttaatt ggagctaggt cagctttatt tgcacctttt aattccttag
    20461 gcttaataat aattgatgaa tgtcatgagt catcatataa gtctgagaag aatccaaaat
    20521 ttaatgctat agaagttgct agatttatgg cattaaaaaa taatataact cttattttag
    20581 gttcagcaac gccctcaatt gaagagtatt atagggcaaa atctggagaa tacaaactta
    20641 taaatataaa aagtagagca aatgataagc ctcttccaaa cattgaagtt gtagacatga
    20701 aagatgagtt agataaagga aatagaagta tatttagttt gaaattacaa aaagaaatac
    20761 gttatgcgat tgaagaaaat aatcaagtaa tactattttt aaacagaaga ggttatgcaa
    20821 attttgtatc ttgtagaaag tgtggatatg tgtttcaatg tgaaaattgt gatatatctt
    20881 taacttatca taagaaaagc aatactggaa gatgccacta ttgtggatat gagaaagaaa
    20941 ttccaaaaga gtgtcctgaa tgtaaaagta cttatgttaa gccatttgga gttggaactc
    21001 aaaaaattga agaggaatta aaatatattt ttccagatat aaaaactttg agaatggata
    21061 aagatacaac ttcaaaaaaa ggtgctttag atgagatact aaataaattt aaagataaag
    21121 aagcagatgt acttattgga acacagatgt taagtaaagg gctggatttt gagaatgtaa
    21181 ctttagtagg tattttgtct gcagacatga tattaaattt tccagacttt aaaagttttg
    21241 aaactacatt tcaattgata actcaagtct ctggaagagc agggagagct gataaagagg
    21301 gaaaagtagt acttcagact tatgacactg aacactatgc tattaagcat gctattgaat
    21361 atgattatga gggtttttat gaagatgaga taaaaataag aaaagcattt ggatattctc
    21421 cttttaataa tatgttaagt gtagttgtta gtggtgaaga tgaaagatta gtgataaaaa
    21481 atataaaaaa tatgcatgca tcattgattt atttattaga aaaaaggggt ataaatgatt
    21541 taggatttat attaggtcca aatccatgtt caatatcaaa aataaatcaa aattatagat
    21601 ggcaaatact ctttaaagat gaaaatattg aaattaatct cttaaagggt ataataaaat
    21661 atatatgtat aacaaaacga gatttgatat ttgataagaa tatcaatgta tctatagata
    21721 ttaatccaaa cagtgtatta taaatttagg aggaattata atggctttaa gacaaatagt
    21781 tcaaatagga gaaccagtat taagaaaaaa atcaaaaaag gttgaaaaaa ttgatgaaaa
    21841 gataatacaa ttattagatg atatggcaga aactatgtat gatgcagatg gtgttggact
    21901 ggctgcacct caagttggaa tattaaaaag agtagtagta atagatattg gagaagagct
    21961 tatagaactt ataaatcctg aaataataga aacatctggg gagcaaatag atgaggaagg
    22021 atgtttaagt gttgttggag aagcgggaaa tgttagaaga ccaaattatg taaaggtcag
    22081 agctttaaat agaaatggtg aaacaataga gttagaggga gaagaacttt tagctagagc
    22141 attttgtcat gagatagacc acttagatgg aattttattt gttgacaaaa tagaaaagta
    22201 gtaggagttg atttgatgaa aatagtattt atgggaactc ctgatatagc agttccatgt
    22261 ttacaaaaaa taatagatga gaagtatgaa atattgggtg ttgtaactca accagataaa
    22321 ccaaaaggaa gaggtaaaaa actaggtatg agtccagtaa aagaactggc aattgaaaat
    22381 aatatacctg tatatcaacc agtaaaggct agagataaag aatttataga taaaattaaa
    22441 tctttaaatc cagatgtaat agtagttgta gcttttggac agatacttcc aaaagaaata
    22501 ttagagattc ctaaacttgg atgtataaat gttcatgttt ctttacttcc aaaatataga
    22561 ggtgcggcac ctataaattg ggtaataata aatggtgaag aaaagactgg tgttacaact
    22621 atgtatatgg atgaaggatt agatactgga gatatgatac taaagacaga agtaaatctt
    22681 gatgaaaata taacagcagg agaacttcat gataaaatga tgaatatagg agcagaaact
    22741 ttaaaagaaa cattaagatt aattgaagaa ggaaatgctc caagagaagt acaaaatcat
    22801 gaagaatttt cctatgcgcc aataatgaat aaatcattag gtaacataga tttttcaaaa
    22861 agtgccagag aaatacacaa tttagttaga ggagtaaatc catggccaag tgcttatact
    22921 acctataatg atgtcataat gaaagtttgg aaaactaaag tgttagatga aaaaagcaca
    22981 aaagatgtag gtacaataat tgatgtaagc aaagatggga taaaagtaag tactatagat
    23041 aatgtacttt taattgaaga aattcagatg ccgaataaaa agagaatgtt ggttggtgaa
    23101 tatataaaag ggaatactat agaaactggt ttagtattgg gttaggtgaa aagtatgaca
    23161 gatataaaga agtatttaac aagtgttggg attttgattt taatattagg aattttgata
    23221 ggagttgtta atttttttat aataagttta actcaaatat tctccttgat gataaatatt
    23281 ataataatat cactaatact tataatacta tgttcaacag tagttactta tagagtaatt
    23341 aaaggaaagt atgttaactc aaatataatg aaaataaatt ttaatattgt cagtggatta
    23401 tttcctatta tatctttcat tgcatcatca tttggtatgt caaaaagtga tattagaaga
    23461 atatatataa agttaaataa tgaatatata tacagtaata aatataattt taatccagag
    23521 gatataataa ttttaatacc tcattgtatt caagagaata gttgtaaatt aaaagttact
    23581 aatgatatag ataattgtaa agaatgtgga agatgcaaca taggagaatt aattaagcta
    23641 aaggaaaaaa ctaatgtaaa aatatttgta gctacaggag gaactctagc tagaaaaatt
    23701 ataatggaca ctaaacctaa agctgttgta gctgttgcat gtgaaagaga tttgacatct
    23761 ggaatacaag atattaagaa aattcctgtt ttaggtgtat ttaacaaaag acctaatgga
    23821 ccttgtgtaa atactaatgt agacatgatg gatattgaaa aagctatagg ctttttaaca
    23881 ggaaaaaata tattagtttg taattaaact gtttttaagt taagtgaata ttaagaggat
    23941 gtataataaa aatatatttt aggagagtgt tatttatgta ccctgtatat ggcggttttt
    24001 ggggatttga cccaacaatg gttgtattaa ttccagctat attacttact atatatgcac
    24061 aatttaaagt gagttcaaca acaaataagt atttaagagt aaatacacgt cgaggatata
    24121 ctggagagca aacagcaaga agagtacttg attcaaatgg tttgtatgat gtaaagatag
    24181 aaatggttag agggcatcta agtgaccatt atgacccaag aagaaaggct gtaaggttgt
    24241 cagaagatgt atattatgga acatctataa cttctgttgc agtagctgca catgaatgtg
    24301 gtcatgccat acaacatgct aaaggttatg cacctcttca aataagaagt agtttagtac
    24361 cagtagtgaa ttttgcttca agtatatctt ggtttttaat atttttagga tttattatgg
    24421 ctggtccatt tttaaaaatt ggtatactat tgttttcggc ttcagtgtta ttccaaataa
    24481 taacattgcc tgtagaattt aatgcttcaa gtagagcaat cgttcaactt gggaatttag
    24541 gtattataga tgaaagtgag tcaagacaaa gtagaagagt actttcagca gcagctttaa
    24601 catatgttgc agcagcattg gtttcaatac ttcaattact tagattgtta ctaatagctc
    24661 aaagaagaaa tgactaaaag taaagtgggt tgtttagaaa caaccctttt ttatgtttaa
    24721 taaaagggag aaatttatat ggatgcaaga gaagttggat ttaaagtatt atgtgatata
    24781 gaaaaaaatg acaattattc aaatattgca ataaataagc attttaaaaa tttagaaata
    24841 agtgatatgg atagaggact tgcaacagag ttaatttatg gagtaataga aaataaatat
    24901 tatttagatt atataatcaa taaactttca aaaataaagg taaaaaaaat gtcaacttat
    24961 gttaaaatct ttttaagaat gggaacatat cagattttat ttttagatag tatatcagat
    25021 tatgcagcag ttaatgaaac tgtaaaatta tctaagaaat atgataaaaa atcttctggt
    25081 ttcataaatg ctattcttag aaatgaaata agagctaaag agactataat ggacataact
    25141 gaggaagata gtgtaaaata cttatctata aagtattcct ataactcttg gattataaaa
    25201 aactggatag ataaatttgg acaagaattt gctgaagatt tgttggaagc aaataatgaa
    25261 aagcctagta tctatataag aacgaataca cttaaaataa gtagagaaga acttattgaa
    25321 aaattaagtg aaatgggtat tgtatgttta aaagttccta tggtagaaga agctattaaa
    25381 gtcgaaaaaa tgaaaaatat agaaaaaaat gaattattta aggctggttt atttacaatt
    25441 caagatataa gttctatgat agtagggaaa gtaattaatc caaaagaagg ctcatttgtt
    25501 ttggatgtat gtagtgctcc tggagggaaa tctactcact tagctacttt aatgaacaat
    25561 actggtcaag tagtagctag agatattttt gagcataaac taaagcttat aaactctact
    25621 gtaaatagat tggggcttaa aaatgtgttt gtagaaagat ttgatgcttc tgagattgat
    25681 gaaaatagta taagtaaatt tgattatgtt ttagcagatg ttccttgctc tggttttggt
    25741 ataataagac gtaaaccaga aattaagtat aagaaagaag aagagttaaa agacatcact
    25801 tctatacaaa agaaaatttt agaaaatgca tctaaatatg tcaaagttgg tggaacttta
    25861 gtatatagta catgtacaat tcaagatgtg gagaatataa atatagttac ttcttttgtt
    25921 gaagaaaatc acaactttga atttgttcca attgatacag taaatgtaga cttagacaat
    25981 caagataaag gatatttaaa gatatatcct aatattcatg gtatagatgg ttttttcata
    26041 gcaaaattaa agagaataag gtagtgagag aatggaaaag aaaaagatag tattaaaaaa
    26101 ttttactgaa gatgaactta aagaatttat gaaaactata gatgaaaagc cctttagagg
    26161 aagtcaaata ttctcttgga tatataaggg tgcaaaaact tttgatgata tgaacaatat
    26221 accaaaaagt ttgagaaata aattagaaga ggtttcatgt atagggcata tagatataga
    26281 attaaagtta gaatctaagg tagataatac aaaaaaatat ttgtttttat tagatgatgg
    26341 aaatataata gaaactgtga tgatggatta tgatagtaga gttactgtct gtgtttctaa
    26401 ccaagtaggt tgtaggatgg gatgtaattt ttgtgcatct acaatggatg gattaattag
    26461 aaacttagag ccatgggaaa ttttagacca agttattaaa attcaagaag atactggtaa
    26521 gagggtatca aatcttgtat tgatggggag tggtgagcca cttgataact ttgaaaatac
    26581 aaaacaattt ttaaaaataa ttaacgaaaa aaatggtctt aatatagggt ataggcatat
    26641 aactctttca acttgtggaa tagtacctaa aatgtatgag ttggcagact tagaaatagc
    26701 tataaattta gctttatcac ttcattcacc atatgatgaa gaacgaagaa aaattatgcc
    26761 tgtagcaaat gcttattcta ttgaagaaat attgaatgca tgtagatatt atataaaaaa
    26821 gacaaataga agggttacat ttgaatattc tcttataaaa ggggtaaatg actcagaaaa
    26881 agaagcaaag gcattagcta agctcctaaa aggtatgcta tgtcatgtaa atttaattcc
    26941 aataaataaa gttgaagaaa gagaatatga aaagccagat aaagcattta tttataaatt
    27001 tagggatagt ttggagaaga acaatatacc tgccacagtt aggatgtcta tgggttctga
    27061 tattagtgga gcttgtgggc aattgagaag aaaatacaag taatttgtaa ggaggaagtc
    27121 gtatggttta tagttgtgcc tcccatatag gaaaaataag aaaaaacaat gaagactatt
    27181 gtgagggaga agttatagat acagaacatg gtccaatagg aatatttgcc atagctgatg
    27241 gaatgggtgg acataaaaaa ggtgaagtcg ccagtaaatt agcagtagaa aatataattg
    27301 attttctaaa ggaaaactta ttacaacatg ataatgtaaa aatagactat atagatgata
    27361 tattaaaaca ggcttataat aatgtaaact caattgtgca caaaaaatct atggaagata
    27421 tagaatttga aggaatggga actacattag ttacggctat agtgtataat aatgtcttat
    27481 atgtggcaaa tgttggagat agcagatgtt atttgttaac agatgaaaaa tttgataaaa
    27541 taactataga ccattccgtg gttgaagaac ttatgatggc ccatgtcatt acagaagaag
    27601 aggcaagaag acatccacag aggaatagaa taactagagc aattggaaca gatgatatgg
    27661 ttgttgtaga tatttttaag aaagaaatca aaaaaagtga tataatactt cttgcgacag
    27721 atggattaac tgggtttatt gatgatgaag atataagaga tttaatatta gattatgaat
    27781 atgagagaac tagtaatata agtgaagaat tgataagtat ggccaatgat gtttctggta
    27841 aagataatgt ttcggttata gtgataaaag tataattagg acggtgatat tgtgggagat
    27901 acaattttag gaaatcgata tgaaatcatc aggaagattg gtgatggagg aatggcattt
    27961 gtatatgagg ctaaagacag attattaaac aggactgttg cacttaaagt acttagacct
    28021 gaatttgtag atgatgatga atttctaaca aagtttaaaa gagaggcaga agcagtagca
    28081 agtctttcac atccaaatat agtaaatgtt tatgatgttg gtgaagatgg aaaagttcac
    28141 tacattgtaa tggagtttgt agatgggaag aatctaaaag agattataca agatgaaggt
    28201 atattagatg aatatactgc attagatata acaaaacaaa tagctatggc acttagtgca
    28261 gcgcacaaaa aggggattat acatagagat ataaaacctc ataatattct catatcaaat
    28321 gaaggaagag tagtaaaagt ggctgatttt ggtatagcca aagctgtttc aaattcaaca
    28381 atgactaata ttggtagtat aataggttca gtgcattatt tttcaccaga gcaagctaaa
    28441 ggtaaatttg taactaataa tgctgacctg tattctctag gtatagtttt atatgaaatg
    28501 ttgataggaa aagttccatt taggggagat agtccaattt ctatagcact tcaacacatt
    28561 aatgatgata tagactttac atcagaagaa aaagttagga ttcctcaaag tgtaagaact
    28621 acaataaaaa agcttacaga aaaatctagt gcagatagat atcaaactgc tgaagaattg
    28681 atagaagata tagagtatat agaaaaaaat attgatttag attttataaa agaatatgat
    28741 gattttgcaa ctaagaaaat tgatgaaaaa gaaattaata aagttgtaaa tccaacactt
    28801 gcaaaaccag ctcctgaaaa agtggttaag cctgttgaag tagctgattt ggatgatgat
    28861 gaagattact atgatgattt ttatgaagaa gatgatgatg aagatgaaga agaggaagag
    28921 ataatgagag ctaaaaagaa tcagagacct aagagtactc caagtaagag aactaagaaa
    28981 aagaagaaaa aacaggaaag cccaaaatct agaagaagat taaaagtaat tgcggctgtt
    29041 ttgatactga tattgtgtgc tcaagtattc ttagcatata agtttttatt tgctggaggg
    29101 tttggcaata aatctttgac tgttcctaat cttgtaaata tgacattaga agaagctcaa
    29161 agtgctgttg aaaaagaagg attatacctg agtgtaaaaa gtgaagagta taatagtgaa
    29221 gttgatgaaa attgtataat atcacagaca cctgaaggtg gaagtacaaa tgtcaaaaag
    29281 ggtgatacta taaatgttgt cgtaagtaaa ggttcaagtc aggcatctgt tcctaatgta
    29341 gtgggactta ctttgagtaa tgcaaaacaa cttattgaag aaaataactt aaaagtggga
    29401 actgttaagt atgaatacag ctcaatatat aaagaaggta cagttttaag tcagagtcca
    29461 ggtgctggct catcaagagc tcaggaaggt gatgaggtaa atctatatgt aagcaaaggt
    29521 tcagaaaaat caaatacaca gactccaaca gtaccagata aaaaaccaac aacaccagag
    29581 aataatacac caacagaacc tggttcaaac tcaggaaaca gtggtggaaa ttcaggaggc
    29641 tcaaattcag gaaatagtgg tggaaactca ggcaataatg gaagtaactc aggaggttca
    29701 aactcaggaa atagtggtgg aaactcagga ggctcaaact caggagataa tggaggaagt
    29761 tcaggaggct caaactcagg agacaatgga ggaagttcag gaggttcaaa ctcaggagac
    29821 aatggagata gttcaggagg ctcaaactca ggagataatg gaggaacttc atcaggaact
    29881 ggcgcaaaca ttggtaaaac agaataaata ttaataaaat aagagctgtc cttttataga
    29941 aaatattttc tttaaagggc agtttgtttt gtataaaata ctgaattggt tataatataa
    30001 ggagaaaagt atttatgaag aagaaaacag ttttaattac aggaggagct agagggattg
    30061 gtaaagctat gtctaaagct tttgcaaaag aaggttacaa tgtattagta aattttaata
    30121 agtcagaaaa tgaagctaaa gagttgtaca ctatattaaa tgaaaaaaat ttttctgtaa
    30181 aactttttaa ggctaatatt tcaaatagag aagatgtaga ggatatggta gattattgta
    30241 taaaagaatt tggaggattg gatgtacttg taaacaatgc tggtgtaagt caagataagt
    30301 tgtttacaga tataactgat gaagattggg ataatatgat gaatattaat ttaaaaggaa
    30361 gcttttattg ttcacaagtt gctttaaaat acatgatatc agaaaaaaaa ggaaatataa
    30421 ttaatatatc ttcaatctgg ggtatatcag gtgcgtcttg tgaagtgcat tattctataa
    30481 caaaagcagg tataataggt atgacaaagg cattagctaa agaagtagga ccatcaaata
    30541 ttagagtaaa tagcatagct ccaggtgtca ttaatactga catgttatct ggatataatg
    30601 aggaagatat agacgctctt gtggaagaaa cccctctaat gaggctagga actccagaag
    30661 atatagcaaa ttgtgctatt ttcttggcat cagacaaatc aaattttatc actggtcagg
    30721 taattagtcc aaacggagga tttgttattt aaaaaaaatg tggtattata taaaaatagg
    30781 aaagaataac acgatatact actcataaac agtatgtgtt tatataaatt ttataaaggg
    30841 aggcatttga tgctagaagg aaaaattata aaggggatta gtggatttta ttatgtagat
    30901 acttataatg gtatttatga atgtaaggct agagggatat ttagaaagca gaaaataaca
    30961 cctttggttg gtgatagagt caaaataagc attgttgatg aagatgaaaa aaagggtatc
    31021 ttagaagaaa tcgacagtag agatacagaa cttataagac ctcctattgc aaatgtagat
    31081 aaagcattaa tagtattcgc aataaaaaat cctaaaccaa acttatctct tttagataga
    31141 tttatagttt tggcagaaaa agaaaattta gaaactgtaa taatccttac aaaagcagat
    31201 ttagatgata atgatacatt agaaactgtt aaaaatatat atgaacttag tggttataaa
    31261 gtcattcctg taagcaatat tactaagtta aatatagata aagtaaaaga agaattaaaa
    31321 gaaaatgtag tagtgtttgc aggaccatct ggagttggaa aatcaagctt attaaatgaa
    31381 atagatgaaa attttaaact tcaaacagga gttgtaagtg ataaaataaa aaggggaaaa
    31441 catactactc gtcacgctga acttttaaaa ttagaatttg gtggaatggt tgcagataca
    31501 ccaggtttta gttcccttgc acttgaagat atagaggaag ttgaacttaa agattatttt
    31561 atagaatttg ataaatttaa tgattgtaag tttggttcaa agtgtattca tgaaaatgaa
    31621 cctaattgtg ctataaaaga agctgttaca aatggagaaa tatctaaaga aagatatgat
    31681 agttatatac agctgctaca tgaaataaga caaaataata gtaggaggta ttagaaacat
    31741 gattaaatta gcaccatcaa tattatcagc agattttgca aaattattag aagatgtaag
    31801 aaaagtagaa agtgcaggat gtgaatatct tcatatcgat gtaatggatg gacactttgt
    31861 accaaacatt acattaggac cacttgtagt caaaagttta aagaaagaaa atataaatat
    31921 ggtatttgat gctcatctta tgatagaaaa tccagaccag tatattgaag aatttgtaaa
    31981 agcaggatgt gatataataa ctgttcacca ggaggcttgt gttcatctac atagaactat
    32041 acaaaatata aaatcacatg gaataaaagc tggtgtagta cttaatccag ctacaccagt
    32101 agatacgatt aaacatgtac tatctgattt agatatggta ttattaatgt ctgttaaccc
    32161 tggatttgga ggacaatcat ttattccttg tgttttagat aagattaaag agttaaaagc
    32221 tattatagat agtcaaggat taaacattga tatagaagtt gatggtggta taagccctaa
    32281 aaacgtagcc gaagttgtac aagcaggagc taatgtaata gtagcaggtt ctgcaatatt
    32341 tggaagtgat gacattcaag aaacagttaa tttatttaga aagaatgctt ctcttgaaga
    32401 attagtttaa atttaataat gaaaatctgt attgttttaa atggcgaaat tgaagattac
    32461 gaagttacaa gagatattat aattaaggaa tgttatgact gcataatatg tgcagatgga
    32521 ggggcaaatc acacttataa aatggaaata atgccagatt atatattagg agatttagat
    32581 tcagtagaag aagaaaagat aaacttctat aaaaataaag gtgttaaatt tgaaaaattt
    32641 ccatctaaaa aagatgagac tgatacagag ctttgtcttt ttttagctaa gacacttaaa
    32701 gcaaatcata ttgatttttt tggtgcttta gggggaagga ttgaccacac tcttgcaaat
    32761 ataaagctat tatattattt aaaagaagat ggtatatatt ctaggatact ttctgataaa
    32821 gaagagatgt atatagttga aaatgaggaa atttcattgt atggaaaccc aggggacact
    32881 atttctgtaa tagctataaa tggtgatgct aagggtgtaa cacttactgg cttagaatac
    32941 cctctcgata attattatat gaaatactct gtacctattg gaatatcaaa tgttatgttg
    33001 agtaattctt gtaagattaa agtagagcaa ggctgtgtac ttgtagttag aaatttataa
    33061 aatttgattt tgacaattgg ttttatattg tagagcagat acaatcaagt aaaatatatt
    33121 tatgattgta tctgcttttt agtatataat tataaatata taataaactt tgacataagg
    33181 gggatttttt gtggtagata gtattatttt tgatttagat ggaacattgt gggattcaac
    33241 tgaagaagta tgcaaagtct ggcaggatgt tttaagtgag cataaggaaa tagaattaag
    33301 tgtcacaaaa gatttattta gaagtcttat ggggctttct tttgaggaaa tagcaaatcg
    33361 tttatttcca aatttaagtg aagaagaaag aatgaattta ttgaatgaat gttctttgaa
    33421 agaatgtgac tatttatctg aaaatggagc taaattattt gatgatatag aagatactct
    33481 taaattacta tctaaaaaat ataaattatt tatagtaagt aattgtcaag ctggatatat
    33541 agaatctttt ttaaaagcac ataaactaga acagtatttt atagattttg aatgtcctgg
    33601 taatactggt ttgcataaag gagaaaataa taaacttata attgaaagaa ataaattaat
    33661 aaatccaatc tatgttggtg atacgcaagg tgatgcaaat agtgctaagt ttgtaggtat
    33721 accttttata tatgccaaat atgggtttgg gaatgtagat gtatatgatt attttataga
    33781 ttcatttaaa gatttgttag aacatgatat attaaaataa gatgagttta aaaattatat
    33841 taaaataata aaaaagttat ggggggattt aaaaatggaa ttacaagata ctatttttaa
    33901 aagacaaagt gtaagaaagt ttaaaaatca agatgtatca gatgaagata ttttaaaaat
    33961 gataaaagca gcaggtgcag caccatcagg caagaatatt caaaactggc attttgttgt
    34021 tataaaacgc cgtgatttaa tggaaaagat agcagatgtg ataactaaaa agcaacaaga
    34081 aatacttgta gaaatggata aagtatcagt ggataaggct aatagattta gaaaatttgt
    34141 taaaaatttt acactatttt acttaaaagc tccagtttta gtattagttt ttacaaaggt
    34201 atataatcca tcaggatatt atgaattaga gcttatagat gcacctaagg agactataga
    34261 taaattattt ataagaaatc caggtatgca gagtctaggt gctgcaattg aaaactttac
    34321 actatcagca attgaacttg gatatggttc ttgttggttg acaagtcaaa actatgcagc
    34381 agatgagata gaagctgttt tagaagcaga aactggtttt gaaaagggag agtatttttt
    34441 aggtgcaatg ttagctcttg gagtgccaga ggacaatttg aagagtccat ctaaaaaacc
    34501 agtagaagaa atatgtacat ttataaaata aaagtcaagg acattttaaa atcgaagtaa
    34561 attaaaaaca aaataaatta aaaataaata tttaaaaaat taaaaagtag gttttattga
    34621 tattaatttt atatttcaaa tcattaattt aattaataca ataagaacta cttttttttg
    34681 tatattaatt ttaaatatat ttaaatcttt agaaaagtat atgtaatatc ttaagttttt
    34741 aattttaata ttaagtatat aaaacaaaat gaaaaaatat taaatttaaa ctagaaggag
    34801 gtttctaaga tggacattaa atacaaataa ccagaacaaa agatataaat atatatataa
    34861 atggaaaaac ttctatcata ttgtataatc atatatgtaa agaaaattta taaattaata
    34921 taaaggagat tagaatgaat tcatataata ttttggtggt agaagatgaa aaggagatag
    34981 cagatgctat agaaatatat ctattaaatc aaggatataa tgtttttaag ggatacaatg
    35041 gattagaagg tcttaaggtt atagaaaacc aagaaataca tttagctata gttgatataa
    35101 tgatgcctaa aatggatggt ataacactta caatgaagct tagagaaaac tataattttc
    35161 cagtaataat gctatctgca aaatcagaag aagttgacaa aataatgggg cttaatatag
    35221 gagcagacga ttatgtaaca aaacctttta agccattaga actattggct agagttaatt
    35281 cacaacttag aaggtacact aagtatctaa acatggttgg aaataaagag caaaaggtag
    35341 aaagtgacga tagtgtgttt gcaataggcg gattagaatt aaatgaaaat acaaaagaag
    35401 ttagtattga tggaaagtat ataaaaacaa ctcctataga atttaaaata ctaagtttac
    35461 ttatgagaaa tgcaggaaga gttttttctg ctgatgaaat atatgaaaga gtttggaatg
    35521 agaatgctgt aaatacagat acagttatgg tacatgtgag gaatataagg gaaaagatag
    35581 aaattgaccc aaaaaatcct aaatatttaa aggtggtgtg gggtgttgga tacaaaattg
    35641 aaaaaattta aagataaata tatagttact attatagttt ttatacttat gttatcagca
    35701 tcattaggta tgattagtca atattctact atacaagcaa gtgctaaagg tggagcagag
    35761 aatccatttg aacaggaaag ctttgtagat agtatatata aaggaagtta tgttttatat
    35821 cataatatga aggaagaaca agaaggtaag atgatacaac catcaaagct atttatcaat
    35881 gaagaaacta tgaactatat aaaaaatgta agtaaagaaa aagatactta tgatggttca
    35941 gaaacttatt atacagatga tagtattaat gcagatttta atgaaaactt tgaaaattgg
    36001 gagcatttca ttaaagcgtc aggaaagaat ttaaagtact atttagttga taaagaaagc
    36061 aattttgaat tttttaatga taataaagaa ttaggagtac ttgatacaac aaaaaatgat
    36121 gcttcaaaag aaaattctaa tgaaaatcag tcaaaaaata cagaaatgaa tgatgaggaa
    36181 agacaaaagc agattacaga tataaaagaa aactatagat tctacgttgt aatgaatttt
    36241 gataaagatg gaaaagtaaa tattgtggat tcttatggag taaatcaaaa aattattaat
    36301 caaatgttgt tatctaaagc aagagaagat ttaatggata caagtttagg aggaaattca
    36361 atttcatata agttatctcc aataaaaaat ataacattag tatatgctgt acctaaagta
    36421 ataagtaaag gtgatagtgt agagtatggt tatggaaata cttattttga tgatggtata
    36481 atttcatata taagcaatgt agaaaataat tcttattata agatttctgg aatgatttta
    36541 aaaattatat tagctatagt tgttattgta gctttagcat tcccatatag aaaatctaaa
    36601 gagttgctag gatttgatac attatcaaga ataccgttag agatactctt tattgctctt
    36661 gctattatac aggggcttgt agatttatat cctactgtta taataagtaa taccttgagt
    36721 gggaattatg tagagtacct tataaacaat gacataagtg ctaaaatggc tagtatattg
    36781 gtaagtttaa tgaatttaac ttattggttt gtaatattct caataatatt tgtatttata
    36841 atacttttaa aacacatttt aaatgttgga ataagagagt attttacaaa acatactgtg
    36901 acaggaatgt tttttgtatg gttaaaaaaa gcaggaaaag cagttattaa tcaaattaga
    36961 acaataaatc tgaaagaaaa gccaaataaa actatagtta caattttggg aataaattta
    37021 ttgattatag ttataatgtg tagtatgtgg ttctttggaa taatactcgc attaatatat
    37081 tcagtagtat tatttaagat actgtcagat tactctaaaa agacaatata tgaatataat
    37141 caacttttag atgttacaaa gaaaatttca gatggaaact tagatgtaaa tatggaaaaa
    37201 gatttaggat tttttaatcc tataaaagat gaattaggaa atattcaaac tggatttaaa
    37261 aaagctgttg acgaagaggt taagagtcaa aagatgaaaa cagagcttat atcaaatgta
    37321 tcacatgact taaaaacacc tctaacatct ataatcactt atatagattt attaaaagat
    37381 gaaagtataa cagatgaaaa tcgtaagttg tatattgata cattagacag aaagtcacaa
    37441 agattgcaac atctaataga agatttgttt gaagtaagca aggcaaatag tggagatgtt
    37501 tatttgaata tagtaaatgt ggatattgta tctctaatga agcagacact tttagaatta
    37561 gatgacaaac ttgcagattc atctctaata gtaaagaata acttttctaa tgaaaaaata
    37621 atattaccat tagatagtca gcgtacattt agagtatttg aaaatcttat aataaatata
    37681 agcaaatatg caatgccaaa ttcaagagtg tatattgata ttttagaaac agataataaa
    37741 gtaaatatta tgcttaaaaa tatgtctgca tctgagattg attttagtgt agatgatata
    37801 atggagagat ttgtaagagg agataaatca cgtaacacag aaggttctgg tcttggttta
    37861 gcgatagcaa aaagttttat agaattacag ggtggtaaga tgaatataag tgtggatggt
    37921 gatttattca aagttacaat tacttttaac aaaaattaga ttagacttct ttaataatta
    37981 taaagtctat agaataaaag aatctggaaa tatttatgtg tattctttaa ataaaaattt
    38041 ataggtattg ttttaaaata atttgtaagc attatttcaa aacagcttat aaatgttatt
    38101 ttaaaacaga atgttgattt atttaaaaaa ggtgaatcct aatatacaag gttcaccttt
    38161 ttattttaca aaatgttatt tagtgttaca gagcttataa atagcataat atctggcttt
    38221 actattaaca tagtactagc aatttatttt gaaatcttgt ataagctatt ttatattatt
    38281 taattactat tgtttgtact ttacaatgtg ataaagaatt tacctctaca gttttagtat
    38341 ttactttaag cttgctagta ttatcataga tttcgtcgag cattgcacta taagcatcat
    38401 tgacattttt attgatgtta agacttccct tagcatcctc atttttcata ccattgaaga
    38461 ttctaactac aattccatct cctttttctt ctttctttat tgcacttact gtgaaatttg
    38521 aattatttac attcatcaaa ctaaattcat tttcatatat ttgtttttcg tcattgaatg
    38581 caaatataag tctaccattt aaaaaatcag catattcata tatttgtata ggtgttaaga
    38641 atctcttagc tgtattagct acatttgctt catcaaattt attgttatat atgtaaagac
    38701 caaagtcaaa gtttaactct ttaagtaatt gtgcatctgg tgttgctatt attttttctc
    38761 cagaagctct tcctggtcta taaagtaaat tttctcttcc catatatcca aatgacctga
    38821 atagtgttaa tgctattgta tctaaattat caccaactat ttgatattct cttacacaac
    38881 cagttattaa tgctattcct ctttgtccat cctctaaagt aacaaaactt tgcattggtt
    38941 cgatagttat aggtttttct tgccatgagt aattgtctct tttccacaat gcaaggtctt
    39001 tttctaatac tgttggtctt tgtattattc caaattgttg atctgctata gaaaacttag
    39061 atgctatttc tgtattaaat aaaactctta ctctatgaga tagtgcttgg ttatttttta
    39121 tattaacatt aaacttaatt atttgttctt taggttctaa ggtgattttc attgttactg
    39181 gcattttcac agaaacttta cctatagccc tttcttccag tgaagttggt atggtcaatg
    39241 aatatttaag tatcatttct tcttgaatgt ttgattttag cacttctact gaagatacag
    39301 aatctaaaga tgaaacataa atatcttttc ttggaggaga atagttgtat gaatctccat
    39361 catctccatt gtcttcaatt acagcttggt ttttataagt cttattagat tctttatcta
    39421 atatttctaa tgaaccattt ttattggctg ttattttgta gtatttgttt tctatttcct
    39481 tgcaattact tgtttctatt tcacatttat ttttagtatc caattcaaaa actagttgag
    39541 tatatcccat tggtggtata tcttttactg aaagtgcaat ttttgctcta tatacagttt
    39601 tgggtatata tattttttta cttgggttta atcttattgt ttgagttaat atataatttg
    39661 taatatcttc tttttctttt attatataat taagaatttt tccattttta ttctttatca
    39721 caaaatcttg acctggaata taagtatcaa attctacaac ttcatttctg acttctggga
    39781 atccattgaa tactgttaat gttatttctt cattattatt tttgatttga gtacttataa
    39841 gtctcatatg caaatctaat aaatttatac tcaaatctct ggcttgtttg tatcttgtgt
    39901 atacatcctc atttgttgtg tcactattac aagaacctat gctgtcatga gctgcatttt
    39961 caaacataag tttccatata tcttttataa ctaggtgagg gtattcattt ccaagtgaat
    40021 aacttaatgt taataatggt tcaagtacat ttgtaatata attttctaat ttgttattca
    40081 ttattttaag gtctgacctt gaggagaata tggatttgtg tattctcata tgtttagcat
    40141 ttaaaaattc acctttaagc tctgtaaatt catttctttc atttcttact gaatctatat
    40201 agttttctat atcacttatt tcgtattcat tttcattatc tatttcatta gcttttttta
    40261 atatatcagg aaggtttttt cttattggtg cttggtcaaa tccatttgga aaatatacgt
    40321 tattagtaga agctttaacc ttaagttttc cgattatatc ttttaaatat tcttttaaat
    40381 cagaatcatc ttctggtata ttacctccat agtaataacc aaatggtatt tgaactgcta
    40441 atacttttga accatcagaa cctttccata taaactctgt tgtatctacc atatcatcag
    40501 aaactccacg ccaaaataat gaactatcta ttccaaaacc tctgtatatt tgtggcattt
    40561 gagctgattg cccaaaagaa tctggtacat atccaaccct cataggttca ccaaattcat
    40621 tgcatctatc tattccatag taaaggtttc taattataga ttctcctgat ataaccaatt
    40681 ggtctgtttg agtataccaa ggtccaataa ctaatcttct tctttgaact aaatctctta
    40741 ttctatattc atcctgaggt ctccatttta aataatcatc taagagagaa gcttgtgcat
    40801 ccatagtaaa gtatttaaag tcttcttttt cttccaatat gtctaatata tcttgaaaat
    40861 ctttcattaa atatattttt gaccttgatg ttgtaaaata ccattctcta tcccaatgac
    40921 tgtgtggaac tacatgtact tttgtctttt tcataaaaat cctcccaaaa tttaattgag
    40981 aattgagagt acactcaatt ctcaattatc taaaattaag tttttaattt acattatatc
    41041 taactctatt tcatcaaatt ctgtattttc cgtagtttca tcttcattga agtctactaa
    41101 agttgttgat aatattgcta ttactaaagc tccaaatatt gcacctacta agtaagccca
    41161 tccagaacct attgatataa atccatataa tccaccaact ggaggcatta tagcatgtac
    41221 acctaacaaa gctgataatc ctacacccaa agcgcatcct atcatattaa caggaactaa
    41281 ttttaatgga tttgttaaag tgaaaggaat tgcaccttct gttattccaa ttatacccat
    41341 aactatattg ccttttcctg tttcagctaa tgcattggaa aactttgatt ttcttatgaa
    41401 tgtagctaaa ccatatccta gtggaggtat aactattgcg cagtttacca atatcgctgg
    41461 tagatagatt ccctctaaca ataatgcatt tcctgccatc caagctgctt tatttactgg
    41521 tccacctaaa tcgaatccta tcattgcgcc taaaattaaa gccaatacca ccgaatttgt
    41581 tccattttga cacatttcag ctacccaagc atttaatgaa gtatttatgt ttcctaaagg
    41641 tcctgctaat acaacactca ttaaaaaacc agttaatcca actgttataa gtggcattat
    41701 tataagtggc atcattcctg atgctgaccc agatatttta atttttttct ttaaaaactt
    41761 acaaacatac ccagcaaaga aacctgctat tactgctcct aagaatcctg cattagtatt
    41821 acttgctatg agcccaccaa taaaacctgc acccatagct ggtttctcac ctattgaaaa
    41881 tgctataaat cctgctaata ccgtatttaa tagacctatg ccagtccaac caacttgttc
    41941 cattaagtaa agaatatgat aaaaaccaga tacattttta taagcatcta aacttgttat
    42001 acccattgct aaagctgtaa gctttgggat agctacaact aaagatgagc ctattacaag
    42061 tggcaacata tatgagatac ctgtcattaa gtgtccctta agttcactta aaagagattt
    42121 atttttttta ctcattttta atcctcctat ataagtttgt tatatttttt gataatatgt
    42181 tataattaca ttagacaatt ttttaatttt tgatttttct cattctatat tagagtgaga
    42241 tttttttatt aagaaatagc ttctatacac tttgttaaga cagcttctgg tttttttaac
    42301 gctataccta ttttgacttt tatcaccttt ttaccatcaa atctttccat tccagatata
    42361 gtttggtcag atgctataag tataaagtcc gcatcttgtg cttcttcttt tgttatagta
    42421 tttactcgtc ccatagcacc ttgttgttct actttgattt catgacccat ttttgatgca
    42481 gcttgttcta aagcttttgc tgccataggt gtgtgtgcta atcctgctat acatgatgtt
    42541 attgctacta ttttcataat tattcctcct tcattttatt agttatatat tttactaaat
    42601 gacttgcatc actagcattt ttaacttcat ttgtaaaatc atcctccatt aaacatgtgg
    42661 ctaatttaga tagagttttc aaatgtatat ttccttcatt tttatgtggg gctaacaaac
    42721 taaatacata tctaacctta ctatcatcta aagttttcca ctctaactcg ttagttgttt
    42781 taatatagag tatggaagct tcctttacat ttacactttt tgtatgaggt atcgcaaatc
    42841 catcttttat tcctgttgga aattcatttt ctctttttag aaggtctttt aaaagagcct
    42901 ctttattagt tgtaatacct agtatataag cactatctgc aataaaattt aatacttctt
    42961 ctttgctttt taagtcttta tctataaata tatatttttc ttgtagtacc atatattttt
    43021 ccactccatt cataatgtct taacttatat ttatattgta atcattatcc taattaaatt
    43081 aaatataact aatttccact tcgacatgga aatttatatt atgataataa ctaatttcca
    43141 tatagaagtg gaaataaatt attataatac aattttatta gagtaattgt attatatgag
    43201 tgtaaatagt ataatttaga agaaattcta taagggggga tatttatgca caagagattg
    43261 ctcacgttgt ttaaattatt aaatgaaagt gatgataaaa ttacttgtaa aactttaagt
    43321 aatcatttaa aagtgagtga gagaactata agaaatgata ttacttctat aaatggaact
    43381 ttagagaaaa atggtgctat tattaaaata aaaaaaggag aaggatatta tatagatatt
    43441 cttaatttag cattatacca acagtatcta gcattaatat ctgatgatat tatggattca
    43501 agtgaaatac cagattctcc tatagaaaga aatcaatata ttttaaaata tattctctat
    43561 aacaatacat atataaaact agaagattta gctaatagct tgtatgtgag taaatttaca
    43621 atactaaatg acataaaaag aataaagcct attttgtcaa agtataattt aatattagtt
    43681 tctaagccat attatggagt taaagttgaa ggtaaggaaa tagatattcg aagatgtatt
    43741 tctaataata tgataaatag gaattttgaa aactatataa ttggaattac agatagagaa
    43801 atagaattat ttaataatgt agatttaata gagcttcaaa gggtagtgtt aagtgaaatt
    43861 aataaattta atatcaattt cctagatttt aatctaaaaa actttattat ccatttagct
    43921 attactgtaa gtagaatact tgatggttac tgcttagata atgttttaga tgttgtttta
    43981 acagattttc aatcgaatac aactgttgaa aatatattta attatattga gagtaaatat
    44041 actataatta tttcaaaggc agacagagtt tatctatata atcattttat aactaaaagt
    44101 tctcttttgg ataacgtttc caatagggta gatactaaaa ttatagagta tgttgaagaa
    44161 attttagaag taatcaacaa tcaatatact tttgacctta gaaatgatag tgtattattt
    44221 gatgatttag tactgcactt taaatcaatt ctcaattcta aatcttataa tttaaataag
    44281 gtgaatcccc ttataaatac aataaagagt aattatcctt tagcatttga aataacttta
    44341 aatgctatag aaaaagtttt taaaaatagt atttactctt taacagaaga tgaaattgga
    44401 tatgtatccc tgcatatagg tgctggaata gagagatttt ttcaaagtaa tattaagtgt
    44461 aaaaacgtag tattagtatg tggttcaggg tatggttcaa gtaggttatt agaggttcaa
    44521 ttaaacaaag tttttcatga taaaataaat atacttcaat gtctatcatt taatcaattt
    44581 ttagctagtg aattgtcaga tgtagatata ataatatcga caattccttt aaatcatgat
    44641 agtattccta ttgtattagt ggatttaaaa ctattaaaaa aagatataga gaatatatct
    44701 aagtcaatca ctaataattc ccatatttat agtaatcttt tggacaattt ctttgataaa
    44761 aatttattta ttgttaatcc taaaatcaaa gataaagatg agcttataaa gttgatgtgc
    44821 aacaaattaa ctcaaagtga aattgtattt ccatcatttg ctgaatctgt attttacaga
    44881 gaaagtttat cttctaccaa tatagatgat tttttagcta tacctcatcc tatggaatta
    44941 agctctataa gaactaagat ttgtatttcc atattggatg aaccaatata ttggagtgaa
    45001 gattctactg ttaaattaat catgatgttg gctataaata aagatgatta tataaaaata
    45061 aactccattt atgatatcct tttaaagata attcatgaca atgatattag agatagtata
    45121 tctaattgta atgattttga taattttctt tccataatca agtctatagt atagattttt
    45181 atattacata agttttaaaa actttaataa aatatttttt gtttttagca taaatagtat
    45241 aagtaagttt tgtataattt gttattattt tgtattgatt ataattatta tacaataaag
    45301 attctgtctc aaaatagaga gagaaacctg tttttcattg ataaaatgat aaaaatatat
    45361 ctgatttcat acaaaaaaga gtgtctcatg aactaaaaag ttcattttga gacaccacct
    45421 ttattatttt atattattta tctcttgtat atattactat agcatccctt aaaaacttag
    45481 ctaatccagg ttgttctcta tcataatatg atgtaaaacg ttcatcatat acatacatct
    45541 gtgctagaga ggaatgagct tctttagagt atgtgttcca agtgtaactc aaccatttat
    45601 gatgtaattt tgcaacttcc tgagccagtt cactagaggc atcaccagtt ttaaaagctt
    45661 ttttaagttt actaattatt tcgatattta ggttttgcca attttcataa tcttgcttag
    45721 acatattttt aagtttttta tttgatgtat ctataatatc tttaccatat ttctctctaa
    45781 tttcagttcc ataatttttt tcattttcat caatcatctt ttctttaaaa ccttcaaatt
    45841 tttctatatc tgtcatagtg tattttccct ccttcagagc tatagtttta gttacatttt
    45901 ctattagtaa atcaatttgc tttcttttgg ctagtaattt attatggtgt tcttttaacg
    45961 cacttaaact atcgaagttt ggtgaattta taatgttttt tatattttct aagttaattc
    46021 ctaattctct ataaaaaagt atttgttgaa gtttattaac ttcattttga ccatatatac
    46081 gataacctga agaatttatt ttaagtggtt taagaagacc tatttcatca taatatctaa
    46141 gtgttctagt acttatacca gctagtttac ttaatttttg aactgtatat tccataagta
    46201 gtacctccta taaattaaat atacactttt acgcaacgta aatgtcaata cattaaaata
    46261 taaaaattta tatcttttaa taaaaatata aaaaaatatc tttactggat attttacaca
    46321 caactgtcaa tactcactaa tgaaaattaa aaaataaaat ttatagacta tctttactaa
    46381 aaaatagagg gtctatagtc taggaggaac tgtatgaatt taaaaagaag caatgaaaaa
    46441 cgagaagagt acagaagaat gtattcagat aaagaaagtt ttttaagttt gattcaaaat
    46501 tttacaagtg tctcaatagc aaaagaatta actcttaaaa atatagagtt agaaacatct
    46561 tttatatgtg aatataaagg aaaagaagtt gatataattt ataaggtatt ttctaaaagt
    46621 ggcaaagtat cacattatat agtgttagaa tttcaaacag aaatggatac tgaaattgtc
    46681 ccaagattga aatcgtatag agaacaaatt tggaaaagtt ttattatgaa aaaaagcctt
    46741 gaagaaatag aagataaaaa ttttaaactt cctaaagtta taccagttgt tttatatagt
    46801 ggacctgaaa ggttaagtag aaaaaaagga attttggata ttgtagaatc tatatcggag
    46861 ttcagtaata attctagtat gaaaaattaa aattacataa tgtgtttatt ggtctaaaat
    46921 ggaaaactgt cgcataaact tgaatatgaa aatatttata gatacaggtt ctatgtggag
    46981 gtgttccatg agaaataaca agtctaaggt attgctagga atactttgtc tagcaacagg
    47041 aatggctgta attctgtcaa tgttgcttcc tggctggatt tggtcagcac ttaccgcatt
    47101 aatacttatt ggatgtggag cattattatt tttttgttaa aatagtttta actataaagt
    47161 gtggggtgag tattgatgaa agtagtaaca ataaaattac caaaatggat ttcaagtata
    47221 atcctaaaat ttatgagaaa gagtaaaaat gattaaatta aaaagcctac ttacggaagt
    47281 aggcttttaa acgtggttac taagctcttt caattttacc agaacgtaaa catctagtac
    47341 aaacttttac tctcttagga gctccatcta taatcgctct tacgcttctt aagttagctg
    47401 accatgttct tttattatgt ttatttgagt gtgatacttg gtttccagaa accttacctt
    47461 taccacatac gctacatact tttgccatct acgcacacct ccttaaaatg ataactattt
    47521 aaagactaaa aacatattta tattatcata aataacaaaa atttgcaata gaaatatata
    47581 tttgccttac acatattgaa gaatttctta ttatcatata aaattatata tataatttta
    47641 tataaagtaa atatatttgg aaaataatta ttatttttct ttgaatatat atactataga
    47701 agaaatttta tccaaaaact tttctaggtt taaattatac catatttata gtatgatatg
    47761 attataattt tatataataa ataagtaaaa atagtaaaaa ataaattaag aaatgttttt
    47821 aataaaaata agcttaaggg ggtcaaccat gagtgcaaag gtaacgaatc aatatggaaa
    47881 tatagaaata gataatcaag taatagctca agtcgtatat agagctgcaa tggaaagtta
    47941 tggcttagta ggtttagcat ataagtctaa aggaatagta gagctattaa aaggcgagaa
    48001 cgcaactaaa ggtgtaagag ttgaggaagt agaagaagat gccatagcaa tcgaacttta
    48061 tgttataata caatatggta caaatatatc tactgttgcc aataatataa tagatagagt
    48121 aaaatatgta gttgaaaaaa tgactggcgt aagagttact agaattgata ttaatgtaca
    48181 aggaataaga gttaagtaat ttcataggag gaaacaaatg attcaatata tagatggtaa
    48241 aaggttaagg gagatgttta tttcaggtgc aaacaatctc caaaacaata aagagttagt
    48301 tgacaagtta aatgtattcc ctgtaccaga tggagataca ggaactaata tgtcattaac
    48361 aatatcttat gccttaaaag aattagcaaa agttgaaaat gataatatat cagatatcgg
    48421 aaaagcatta tctaaaggtt ctttaatggg agctagagga aactcaggag ttatactttc
    48481 acaaataatc agaggtatag ctaaatctat agaaggaaaa agtaaattat caacagaaga
    48541 tttagcaaaa gcttttaaaa atggttcaga cacagcatat aaagctgtaa taaaaccaat
    48601 tgaaggaact atacttactg tagttagaga aagtggagag tttgcaataa aaactgcgaa
    48661 aaaagagaaa gatgtagtaa agtttttaag tatgcttgtg aaggaatcaa attcttcatt
    48721 agaaagaact ccagaccttc taaagaatct aaaagaagct ggtgtggttg actctggtgg
    48781 aaagggtctt gtacttatat atgaaggaat gttagcttct ataaaaggcg ataacataga
    48841 aataaaaaat gttgacctag atactaatat ttcaacaagt atggattttg caaagagtac
    48901 tactagcaca gatgatataa aatattgcta ttgtacagaa tttattttag aaagttctaa
    48961 ggtagaagat actaaaataa gagacataat gatggcttat ggtgatagcc tagcagtagt
    49021 tggagatgat ggagtcataa aggtacatgt acacactaat gacccaggaa atgtacttca
    49081 agaagctcta aagtacggtc aattattaac tataaaaata gaaaatatga agttacaaca
    49141 tgaaaataca ttactggatg tagaagaaaa gaaagaaaat gatagtgaac ctttagaaga
    49201 agaaaaagag tttgggttta tagctacttc tatgggtgaa ggtttggcaa atatatttaa
    49261 agatttcgga gttgaccata taatagaagg tggtcaaact atgaatccaa gtactgaaga
    49321 ttttatgaat gctataaagc atataaatgc taaaaatata tttattttcc caaataacag
    49381 caatataata atggctgcta atcaggcaaa agaattgagt gataaaaata taatagttat
    49441 acctacaaaa aatacgcctc aaggatttgc tgcattagta acttttaatg gagaattaag
    49501 cgaagatgaa aataaagaag ctatgatgaa tgctttaaac tcagttaaat caggtcaagt
    49561 aacttttgct gttagggata cagtgatgaa cgaaattgat gttaaagaag gtaatataat
    49621 tggaattgca gaagggaatt tattatcagc aggagattat gtggatgaag taacatcaaa
    49681 ccttattgaa aagttggttg atgaagatac tgctataata acattattct ttggtgaaga
    49741 tgttacagaa tctcaagcaa atgaactacg tacttcttta gaagaaaagt ttgaagatgt
    49801 agatgtagag ttatattatg gaggacaacc tctttattat tacttaattt cagttgaata
    49861 atgattataa gaacctgtat gaccaagtag cttttataaa attggttgta caggattttt
    49921 gtgtagtagg tgatatattt gttggattta tataaagatg ttcaatatgt taagggaata
    49981 ggacctaaaa aagcagataa attaaataaa ctgggtatat ttacactaaa agacctattg
    50041 tattattttc caagacaatt tgaagataga aataatctaa agaaaatagc acaattagaa
    50101 gatggtgaga aagttacgat aaaagcagta atatcaagta taaatacatt tagcccaaaa
    50161 gaaggtatga ctttaacaaa gattgatgta aaagatgaga caggctcggc taaagtagtg
    50221 ttttttaata agagttatat aaaaaatact tttcgtccag gagattcaat attagttttt
    50281 gggaaggtta agaaaaaatt taataactta gaacttacat catgtgaatt agaatatctt
    50341 actaattcac ctaagaatac atgtagattt atgcctgtgt accagcttac atacggtgtt
    50401 acaaataaag aaattatgag tataattaga acagtacttg aagataaaga attaattata
    50461 caagaatata tgccacaaag aattatagaa aaatataggc tatgtagtat agattttgca
    50521 gttagaaaca tacattcacc aagtagtaag gaatcattaa aaatagcttt atatagaatt
    50581 gtatttgaag aattacttat actacaacta gggttgtttg tatttaaaag tggcagaaat
    50641 aaagaagatg gaataaagtt tgaaacaagt aaagacttaa aaaaaataat aagtgcttta
    50701 ccatttaaac tgactaaagc tcaaaacagg gcattagatg aaattataca agatatgaat
    50761 ttagagaaaa taatgaatag attggtacaa ggtgatgtag ggagtggtaa aacagtagta
    50821 gctctcttag cacttgcaaa ttgtgtttta aatggttatc agggcgcttt gatggcacct
    50881 acagagatat tagcagggca acattatatt tcacttactg agtctctaaa agattttgga
    50941 ataaatgtag gtctattaat aggtagtctt acaaaaaaac aaaaggatac agtattggaa
    51001 caaataaaga ataatgagat tgatatatta ataggtacac atgcactaat tgaagataag
    51061 gttgaattta ataatattgg tttagttata acagatgaac aacatagatt tggtgttatg
    51121 caaaggagca aactttcatt gaaaggagca aatcctgata tattagtaat gacagcaaca
    51181 ccaataccaa gaactttagc acttatactc tatggagatt tagatatttc tattatagat
    51241 gaacttcctc caggaagaca gccaatagaa acaattgcta ttgaaaaaag taagcgagat
    51301 agagcatata ataaccttgt aagaagagag gttgaatcag gaagacaagt gtacattgta
    51361 tgtcccttgg tagaagaaag tgaagccata gaagccaaat cagcagttga acttgttgag
    51421 gagttaagag cggaatattt tcacgactta aggcttgggt tgcttcatgg taaaatgaag
    51481 tcaagtgaaa aagatgaagt aatgagactt tttaaagata aagaaataga tattttagtt
    51541 tcaacaacag taatagaagt tggtgtcaat gtgccaaatg caacattaat gataatagaa
    51601 aatgcagaaa gatttggact tgcacaatta catcagctta gagggcgagt tggaagaggt
    51661 agtcataaat cgtattgtgt actaatttat gattctaaaa cagatgtatg tagacaaaga
    51721 atggctataa tggaagagac caatgatggt tttaagattt cagagaagga tttagaaata
    51781 agaggacctg gggaattttt tgggacaagg cagcatggtc ttccagaact taaggtagca
    51841 aacttattta agcatataaa aatactgaag ttagcacagc aagaagctcg atatatattg
    51901 ggtgaagata ataatctaca attaaaagaa aacatggcac tcaaaaaaga aattatagat
    51961 aaatttaaag atacattgaa agaaatttca ttaaattaat tttaaattgt gttaaaatat
    52021 tactaatgta ataatgtgct gaagggagat tgtcatattg agagtaattt caggaaaagc
    52081 gagaggatta aaactaaata ctccaaaaaa tgaagatgta aggccaacta cagatagagt
    52141 aaaagagtct ctatttaata tgataaattc atatataatg gaaagtgaag ttctggattt
    52201 atttgctggg actggttctt taggaataga gtgcttatct aggggtgcca agtcatgtac
    52261 ttttgtagat atcagtaagg aaagcataga tattgttaag tccaatataa aaaaggcaag
    52321 agttgaaagt gaaagtatta ttttaaacct tgattttaag actgcaatag ataaacttaa
    52381 attacaaaat agtaaatttg acataatttt tatggaccct ccgtattata aaaatatgtt
    52441 tatagaagct attgaaaaaa ttgataattc taatctattg aacgaagatg gaataatagt
    52501 tgtagaacat gatacgaatg atttatttcc agataagata tgtaaattgg agaaaactag
    52561 agataagaaa tatggaaata ctacattaac tttttataag atggaggcat aatatggaaa
    52621 ataaacctag aaaagctata tttgcaggaa gttttgaccc aattactaat ggacatttag
    52681 atattatttg cagggcttcg aagttatttg acgaattaca aataggagta ttaaataatc
    52741 ctaataaaaa gggtctattt agctttgatg aaagagtaaa acttatagaa aaaagtacaa
    52801 gccatttaaa taatataaaa gttgtgactt ttgatggttt attaataaat tactgtcagg
    52861 aaaatgggat tggagcatta gttagaggtg tgagaagtgg tgctgatgtt gattatgaac
    52921 ttcagatggc gcatatgaat agagagctta atccagatat agagactata attttaccaa
    52981 gttgtacaaa atattcattt ataagttcat ctttaataaa agaggttttg ctctttgatg
    53041 ctgatataaa aaatttggtt ccaaagattg ttttggaaga attaaagaaa aaaactagtg
    53101 ggggtaattg atatatgaag atagatttag aaatgattga actatttgag cagttagagg
    53161 agatatttag aagtgcttct acaatccctt tctcacataa atgcacagtg gataaagatg
    53221 aggttttagc aataattaat gatataagaa ctttaatacc agaagaagta acacaggcag
    53281 tatggattaa taaagaaaga aataaaataa taagtcaagc taagcaagat gctacaaata
    53341 tagttgaaca agcgaaaaaa gaagctgaga gaatacaaca agaatatcaa gataatatag
    53401 aggaattaaa gaaaaattct gaagatgtag taaaggcata tgtagaatcc agtgaacctg
    53461 ttgttcaagc agaccaaaga gcaaaagata tagttgatag agctgagaga atagccaatg
    53521 agataagaat tgggtcaatt gaatatgcag aggatgtgct ttctagtgtt gagtataatt
    53581 taagagaaat attagaagaa gtaaaaagag ataaagctga acttagacct aaaaaataaa
    53641 ttttaaataa ataaaaatgg agctatcaca caaaaaattc caatttatgt gtgatagctc
    53701 tcttttaata tagcaatttt ttgttatata attgtgcttt ttagattact tatatcttat
    53761 tttgatatta taatgtagtt taatctttta tttgttgaaa tcaacttatt tatttgtata
    53821 aataatatag gttattttca aattttttta ataattttac cactgtcttc ttttagatta
    53881 gagttagact gtgcaaaatt ataaaataat actaaatcat gtgcaattat ttggtatggc
    53941 actacatgta gaaaatatag ataataaaat taaggaggta gtatgaagga aagggctaaa
    54001 aaaatattag attttattat taaaaataac aatgtaacat cacaagaact acaagaaaag
    54061 tttaatgttt caaagagaac tatttattac gatattctag ctataaatga acaactagga
    54121 aaaagtggta atataaaaaa tgtaaaacac aaatttatat ttgaaggtaa tttatgtgat
    54181 gcaaggaaaa taatttcaac tgaagaagat aaatttttag atagtgatta cagaaaaact
    54241 tttatattaa acaagatatt acttggcgaa aaaatatcaa tagaaaaact aacaaatgaa
    54301 atgttacttt caaaaaacac agtagtacaa acaataactg atgtaaaaaa ataccttcaa
    54361 acaatggggt taagattaga gtataaggga aagtacaaaa ttataggtga tgaatacgtt
    54421 attagagagc tgtttctgat aattgttcaa gaaaatgtac tggaaattaa ttctataagt
    54481 gaggaagtaa gtagtttcga tacaaaagga catataaaac ttactgatta ttctttatta
    54541 aatctaacta agtttgtgga atttctaaat aaaaggataa gagatgggaa aacattatac
    54601 tcatataaat atctaaatga agctaaaaaa attagttact ttagtaattg taaagaactt
    54661 ttatgtgaag aagctaatga aaatgaacaa gcctatatat gcacttacat aagttcactt
    54721 cccagcttaa atagtgaagt taaggaagat gttgttgaag aatatgtaga taaacttata
    54781 gataagtttg aagtaaatac agcaataaaa ttagaaagta agcatgagtt taagaaaaat
    54841 attttaaggc acctccactc ttcttacaac agaatacgat ttaagtttcc tattagaaat
    54901 ccaatgttag atgagactaa gtataaacat gagtcacttt ataaaattat aaaatcaatt
    54961 atagagaatg aagaagagtt tcctgtattt gaggggataa gagaagaaga aataggattt
    55021 atagcagcgt attttggagg atatttaaga gggtctaggg ataatggtct aagaagaaat
    55081 aaagtcttac tagtttgtcc taatggtctt atggtatcaa agagtttgga aatacaacta
    55141 tataaataca taccaaccat agaaatagta ggtatagtat ccattaagca actaaaagaa
    55201 gtaaatgtat actacgatta cataattaca actatagata tacaaaatgt aaacaacgta
    55261 attgttgtaa atcctctttt aacatcatca gatgttcaat tacttatgaa caaactaata
    55321 agtgtaaaag aaaacgagaa gtatttcaat cttgaattaa taatacaagc tataagaaaa
    55381 aatggagtta tcaataatga agaagcacta aaagctgatt tattaaacat aatacacaag
    55441 atagatgaag gagagatgta tcaaccaatg ttaaaggaat taattaatgc agaaagggtc
    55501 aatataataa aaaatgttag agattggaaa gaagcaataa aaatagcctc aaagccattg
    55561 ttagaagata actctataga agagttatat atagaaaata tgataaagtc agttgagaaa
    55621 tatggaccat atattgtttt agctgataga tttgctctac cacatgcaag ttctaaagaa
    55681 ggagtaaaca agcttgctat gtctttacta atagtagaag atgaagttga tttattagga
    55741 aaaccagtaa atatatttat ggtattagct gctgtagata acactactca cattagagca
    55801 ttagcatcac tatcagagat gatgtacgag gaagaaaatg taaaactaat aattaatggt
    55861 gataaaagtt caataataga acttataaat aagcaaaatt agggggaatg aaaaatgaag
    55921 atattagcag tatgtggttt tggtgtaggt tcatcaatgg tattaaaaat gacaatccaa
    55981 aaggctctaa agcagttagg tatagaatgt gaagtagaaa atacagatat aaattcagct
    56041 agaggtgctg attgtgactg tatattcaca agtcaagaat tgttaaatga attaaaagga
    56101 acttgtaatg tagatgtata tccagttaaa aagtacatgg atttagcaga agtcacagaa
    56161 gttgttcaaa cttttttaag tgataaaaat gataagaaat agtataagtt ttaaaaagta
    56221 aatttaagtt aatcagaata aaataaaaac ttactaagtt caaaaatagt aagaaagaga
    56281 ggagggattt agtggtagaa aacttaaaca gttgacctat cactaaaaaa tataatgctt
    56341 gattaaaaaa tagctacgca cactcgtgac cttagtcatg agttagtagc taaaatagtc
    56401 agcatatagg gaaacctata tgtagagata ggatagaacc tatccaatac tacttgaatt
    56461 gctggaaacc cctaaagcta accaaactaa aacataagga tgaaataaac ctaagtgtga
    56521 aagttacgaa agtagaaaaa attggttaga tggtataagg ttaaacccta agtactttaa
    56581 aatgggcaat cagcaggtaa gctccgaata ggagaaactt caacgactat tcctcttgag
    56641 ggaagtacac tacaagctat tggtagtgga agtgggtaga ccttaacgga taatgccgaa
    56701 ggataagata tagtctgtgc ttacgtgaaa gtgtaagaag ttcataagag aactgcatag
    56761 gtagtagcga acttatgtga acgacaacct caaaaatgat aaaagttaag aacttacggt
    56821 tcttatatat gttatttaaa aataaatata aaaaaccttc aaaatacttg ttttaagtaa
    56881 ttgcatattt taatattatg ataagtgatg aaaaatggaa gttactcatg gtagaggata
    56941 tgcatatagt atgtcaaata tagacatcca ttattatggg gagacatctt tggaatccta
    57001 gttatttcgt tgctactgta ttagaaaata cagaggagca gataggaaaa tatattaata
    57061 atcagaaaaa acaagtaaag tgaggtgata gtagtggaaa aagcttataa gtttagaatg
    57121 tatccaaata aaaaacagca agagttaatt aacaaaactt ttggatgttg tagatttgta
    57181 tataataagt atcttgctaa aagaatagaa gtttataaaa acgataaaga aacttttact
    57241 tataaacagt gtagttctga tttgaccaat ttaaaaaaag aattaaagtg gcttaaagaa
    57301 cctgacaaat tttcactaca aaacgtctta aaagatttag ataatgcata taaaaaattc
    57361 tttaaagaaa aagcaggatt tcctaaattt aaatcaaaga aaattaatag attttcatat
    57421 aaaactaact ttacaaatgg aaacattatg tattgtggtc aacatataaa actacctaaa
    57481 cttggtatgg ttaagataag ggataaacaa gtacctcaag gtagaatact taatgctgct
    57541 atatctaaag aaccaagtgg tagatattat gtatcattat gctgtactga tgtagatatt
    57601 gaagcatttg aaaatactaa taatcagata ggtttagatt taggaattaa agaattttgt
    57661 atctcaagtt gtggagaatt tatagaaaat cctaagtatc ttaagaagtc attaaacaag
    57721 cttgctaaat tacaaagaga attatcgaga aaaacaatcg gtagtttaaa tagaaataag
    57781 gcaagattaa aagttgcaag acttcaagaa catatagcta atcaaagaaa tgattttcta
    57841 caaaaactat ctactaaatt aataaaagag aatgatatta tttgcataga agatttacaa
    57901 gtaaagaata tgattagaaa tagtaaacta tctcgcttaa tttcagatgt atcatggtca
    57961 gaatttattc gtcaattaga atacaaggct aattggtatg gtagacaaat tgtaaaggta
    58021 ggtaaattct ttgctagttc acaaatatgt aataaatgtg ggtataaaaa cgaggaagtt
    58081 aaggacttaa atataagaga atggatttgt cctagttgta atgaaactca cgatagagat
    58141 ataaatgcaa gtataaatat attaaaagaa ggattaagac taataacgat tcaaaataaa
    58201 taacatatgt aagaaccgta ggaactacgg ggatagcctg tggagaatta gtaagacata
    58261 ttttagtatg caaaattcta tgaagcagga accctgtgac tttagtcatg ggaggttcag
    58321 tttatttcaa ataatatttt acgtaatcca tctatgttaa ttggattaat agcagcattt
    58381 ggtcttgtac tacagaagaa gaaagcatct gatgttataa aggggtcact acttgcagct
    58441 ttcggaatta taattatgga gactggaaca ggtatgttag ttagttcaat agcaccaatt
    58501 aatggagctt tccaaagtat aagtggtggt gcagtaacaa aaggtttaag tgatgttact
    58561 tttactgcaa gttatggtgg aattataggt ttagcaatgt ttgcgggttt agctattcac
    58621 ctaatgatag caagatttac tcctattaag acaatcttct taacaggtca catgctttat
    58681 tggttcccat tcatatttgt agcttcagga gttgaagctg gattaaatgg tggagtatta
    58741 ataacttttg cagcagtatt atcagcactc tattggtcaa taatgccttg gttattaaga
    58801 aaatatgtgt ttgatgttat aggagatgat tcttttacat taggtcatcc atctggttgt
    58861 ttagcactta tatcaggatt tgttgctaaa ttagtaggaa ataaagaaaa atctacagaa
    58921 gatataaaca tacctcaaag tttatcattt tttagagaaa tatctataag tggtggaatg
    58981 gcagtgtttt taatgtttat agttgttggg atagtaatac caggtgcgtt taaagatagt
    59041 aatgagttta ttggaacgta tgcaataaag caaggtcttt cttttggagc aggtcttata
    59101 ataatgcttc atggggtaag aatgctaata aatcaaataa tgccagcatt tcaaggtata
    59161 tctgaaaaag ttgtgccaaa tgcactacct gcttttgact gtccaatatt atttaattat
    59221 aaaccaaatg ctgtattaat aggattctta gttgctatgc taacatctac agctatgatt
    59281 ttaatatata actactttaa tgtatttaat ttgctactta taccacttgt tataacttca
    59341 ttctttgagt gtggagcagc agcagtaata ggagaatcac aaggtggtat acgtggagct
    59401 ataataggta cagctatagc tgcaatattt atggtagttt tagtaggaat atctgctgta
    59461 atttactcag gaactattca aaattggata ctaatatttg gaggtaatga cctttcatta
    59521 tttggtataa tcagtaggtt tataggttca ctatttggag gaatattata gatatgaaat
    59581 ttaaatacat agatgagata agaagattaa ttgatataat agaaaacgaa gaaaaagtca
    59641 atatggaaaa agcagtacaa atctttgttg aagcaataga aagtaaaaat gctatatttt
    59701 catttggagc ttcacatgca ggaatattaa cagaagaatt attctataga gcaggtggct
    59761 gtgttcttat aaatccagta tttgcaaaat ctctaatgtt agatacagcg cctataactc
    59821 acacaagtaa gatggaaaga ttagaaggat atggtacagc tctagctgat aaaactccaa
    59881 ttaaaaaagg agatgtagtt atagttcatt cagtatctgg tagaaatcca gtaagtatag
    59941 agtttgctat gaaagctaag gaaaataagg caatagtaat atgtataact aatttaagtt
    60001 actcaaaaag tgtatcttca agacattctt caggaaaaaa actttatgaa gtatgcgatt
    60061 tagtgataga taatcatggt caaaagggag atgcctgtgt agagatagat ggattaaacc
    60121 aaaaagttag tccaacttct actgtaatag caactactgt gatgaactct attatagctc
    60181 aagctactca ggaattagtt aataaagggc taaagaatcc tccgattttc tatagtgcca
    60241 atattgatgg tggagatgag ttaaataaga agatttttga tgaatataaa agtgtaattc
    60301 attatgaata ttaaggttaa aaaaatatgt taatgaactt tgaagtttat caacaaagaa
    60361 tattaataat atataataaa tgctatcatt taaaagctgt aggtaaaaat ctacagcttt
    60421 ttattattgt agattaaaaa gatgcgtaat taaattttaa attggagaaa ataaattgga
    60481 aggtatcaat tataaatatt agaaacgttg tcatagaaaa aaactatatt aaaaaaaagt
    60541 acatagaaaa aactgattag acaataaata catgctttga taatatttta aatggaatga
    60601 aaatgtgtag aattataatg aaaaaagaaa ataaaaatga aaaaagaaaa taaaatggag
    60661 ggaataaaag tgggtatgtt aaaaaaatta tgttcactag ctatggtagc aattatgact
    60721 acaacactta taacagggtg ttcaagtgga aatggaaaag attcaaaaaa ggatggcgaa
    60781 aaagaaaaac tagttctttg gatgccacca gtagaaaata atatgaagga agtttgggac
    60841 cctattttag ataaatttga ggaaaaaaat aactgtgaag tagatttaca gataattcct
    60901 tgggataatt attctgaaaa atttgcaaca gctataagtg ctggcgaagg tccagatgta
    60961 ggatatatgt atgcagaaat gtatccacag tttatagaaa gtggagcagt agaagatttg
    61021 actaactatg caactaaaga ggataaagag caatctattt atataaaaac atctgaaatg
    61081 atgggtggaa tgtatggtat gccattccaa gcagcaaatc caggggtatt atactataac
    61141 aaggatattt tagagaaact aggagaaaaa cctcctaaaa catgggaaga ttttaaaaga
    61201 atttgtaaaa aagcaacgca agatactgat ggtgatggaa agatagacca atggggatta
    61261 gctcagggat ggggagctaa aacttttggt aacttaaact ggaactggta tccttattta
    61321 tggcaagctg gtggagatat atttaatgat gatttaaaat cggttaaatt taatgataag
    61381 agtggtttag aagcagctaa tttcttaaaa gaattacaag catatgtgcc tgaagattct
    61441 ttatctaaag atagtaatga aatgatagaa agcgtatttg gaccagggaa agcagcattt
    61501 acaataatgt tatcttctgc tgcaacaagt gtatttgatg aatcattccc ggatttaaat
    61561 tggggatttg taactggact agaagataag aaagcagcaa cttttggagc agtagaccat
    61621 ttatctttaa tgtcatctgc taaaaataaa gaacttgcat acaagttaat acaacatatg
    61681 ttaagtgttg aatcaatgac agaatttcat aaagcaatac caagagcacc aataacaaaa
    61741 ggtgaaccat atcaaggtga tgaaagattc aaagaaatgg tggaaaatga caaaaatgta
    61801 tatagaccat tagtagtagg acctcatgga gttgaaatat atgaatattt atggaaagaa
    61861 cttcaaacta tgatttcagg agataaaact ccaaaacaag cgttagatga tgctgcaaaa
    61921 tattcaaatg atttattagc acaataaaag tttaaagctg taatatgttg taaaggactt
    61981 tacagattaa aattagcatt gtatttataa atacaatgct aatatttata ttggagagga
    62041 taaaatggaa aacttagtta gagagtttga agaaaattca aaaagaaaaa aaacaaaatt
    62101 aaatattaaa ccatatatgt atatattgcc attgggaata attttagtgg cgttttatgt
    62161 gataccaata ataatgtcaa tatactttag ttttacaaag tataatatta ttagtccagc
    62221 tacttttata ggtttagaaa attataaaaa attatttaca gatgaaacat taaaagtatc
    62281 tattataaat actattaaat ttactgttgt tgtagtacct tgccaaacta tattatcatt
    62341 gattttggct gtttggatta caggaaaagg aaatagtaaa atagcttcat ttgctaaagg
    62401 tgctatattt ataccagtat tatcatctat ggttttgata ggtatggtat ggagggcttt
    62461 attgaatgga gaaggttcta ttatatatca ggtattaggt gcctttggaa tagaatcatc
    62521 taaactttta ggagatagta agacagcatt acctacactt atgtttatat ctatgtggaa
    62581 aaatataggg tattttatgg taatttatat ttcagctata atgaatttac caaaacactg
    62641 ctatgaagta gcgaaggttg atggggctac aaaacttcaa gaatttataa aaataactgt
    62701 acctttattg aaaccaacta caataatggt tgtattttta gggtcgatat ggtcattaca
    62761 agtatttgac ttaatttata ctgtgacagg tggaggtcca ggtatatcta ctatgagtat
    62821 agttatgcat gcatttaact taaactttaa aaactttaat tctggatatg caatgactgt
    62881 agcaaacgta ttatttttgt taatagcagt agtttcgatt ttacaaaata agcttgtaag
    62941 acgagacaat tcagattttt agaaaggtag gtataatatg aaaacagcaa gaagattatt
    63001 aagtgatggt ttgcttttat ttatagcgtg tgcaagtttg gtacctttta tatacatgtt
    63061 gataatatca ttgaagataa catataactc atatagtttg gatatatctt tttcaacagt
    63121 aacccttcaa aactatatag atatttttac taaaaaagga tttgcacaat atttttttaa
    63181 tacagcaata gtatcttttt caggtgtatt attaaattta gtatttagta cattagcagg
    63241 atattctttt gcgaagatgg attttaaagg tagtgataag ttatttttat ttatgataat
    63301 gactttaatt ataccttccc aagttacaat gataccacta tatataataa tgaaacactt
    63361 aggatggata aatagttatc ttgcacttat tatgccaata ccaactgcat ttggcgtatt
    63421 tataatgaga caagctattt taggagtacc aaaagagtta ttagaatcag caaagataga
    63481 tggttgttcg gattttagaa ttttaataca aatagtgttg cctttaatta aaccagcatt
    63541 aattacacta gcaatattta cttttatggg agcatggaac gagtttatgt ggcctcttat
    63601 agctacaact aaagatacaa tgagaacatt aacagttgga ttatctactc ttaagacatt
    63661 ccagataact aattatggac agatgatggc aggggctaca ataacatttt tacctccatt
    63721 tattttctat ttgattttac agagtaaatt tgttgaaggt gtgtctttgt ctggtataaa
    63781 aggttaaata gtctaattta ataatatata aagaaactta tataaatatg gaggaattta
    63841 aactatggaa atttcatatg tactgaaaga ttgcacattc aaacacaata aatactcagt
    63901 tgtagaagct gaaacttgga aagataagga tttggatatt gtagtagcta aaggtgaaaa
    63961 atttgcattt caaattatgt taaaagcaac agaagaattt aattgtacaa ttgataaaag
    64021 tagtgctata tcatggaaag gcctgggaaa tagagtaagg ttagcattaa atatgcctaa
    64081 tagtttagaa aataatttta gtataaatat attaggatat gttcaagatg atacaaaggc
    64141 atttgtgaat gatgctattt taagggataa agatgtgtta gtagagcaat atttgcctca
    64201 aacattttgg attgaaggtc aagtaccaga agattttgaa gaaaataacc ttgatatagg
    64261 tattgatata tttaaaagct ttggatatga agacgaagaa aaagtttgta caattgatgt
    64321 tcctgtaaaa gtaagaaatg ttgtgctaaa gcctttagat gaaagcaagt tctttttaga
    64381 tttatggcaa catccaagct gtttagctag aatgtataaa gttgagttat ggtctgatat
    64441 acattttgaa atagtcgata actatttaaa agaattagca tctttaggag aaaaagttgc
    64501 aacagttata gtttcagatt atccatgggc agggcaaagt tgttataaag tttataaaaa
    64561 tccatcaaac ttatatgaat ataacatggt aagtgtatca aaaggattgg atggaaagat
    64621 taaatgtaac tttgagagta tggataggta tataagcata gctgataagt ataaaatggc
    64681 taaggagata gatttatttg gtctattagg taattggtgt gctggtgagt ttggaaatcc
    64741 tgtagaaggt tataaggacc ctataagagt aagatatttt gatgaaaagg ataaagtatt
    64801 taaatttata aacaatacaa atgatttaaa agaatatata ggattagtat taaatcattt
    64861 aatagagtgt ggattatggg acagagtaag gattatagct gatgaaccaa ataatccaga
    64921 agtagtcaaa gagtgtatag aatttataaa ttctactgta agcactcatc aagttaaata
    64981 taaatcagca actcacgacc aaaacttttt agacagagct aaagatgaaa ttgatgatat
    65041 gtcaataaat ttaaaactta ctatacaaaa ttataaagat atagaaagtc ttaagaaaaa
    65101 aatcaatgac aagggtggga tattgacttg gtttgtatgc tgttttccag agaaaccaaa
    65161 tagtttttta agttctcctt ttgtagaaaa tagaataata ggatggtata cttattactt
    65221 tggtcttgat ggatttttaa gatgggacta taatttatgg acagaagacc cttggaaaga
    65281 ttcaagttac aaattcccta tttggaaagc tggagatatg ttctttgttt atcctggaaa
    65341 agatttaaag ccagttagaa gtgtcagaat ggagaattta agatttggaa tacaggactt
    65401 tgagttattt acaatgttag aaaaagaaaa gggaagagag tatatagaag ttgagcttat
    65461 gcaagaatta ttaaataaaa aagaaaatgc tgaaattaaa ggttttggtg acatagaact
    65521 aggatattca cttgataatt ggggatatga taaagttaaa aaatatgtat tagagttgtt
    65581 agacagagta taaaaaatat aagagtgtct caaaatgaac tttttagttc atgaggcact
    65641 ctttttgtat gaaatcaata tagtttcatt gtttcaacaa tgaaaaatag gattatttct
    65701 attctaagac agccctttag ttttttagtt gtattcaatg ttttaaaact aactataaac
    65761 gctataaagt ttataaatga caataattat atataacatg atgtacttta atttgctata
    65821 atagggattg aataatatta tatggaagat aacattgttt ggggggatta atataaaaag
    65881 aataggtatt attataatgt tttttttaag tatatctttt attggatttt atcttgtaat
    65941 aagagataac agtgatacag ttaagatgca acgagggata aatataggta atgcactaga
    66001 atcacctaag gattttccgt gggatgtaaa aatgtcaaat aagttttttg atgatataaa
    66061 agatgcaggt tttgacacag tacgtatacc agtaaggttt tctgattata cgtcagattc
    66121 tgataatttt aaaattgatg aagaattttt taaaaagatt gataaatatg tagattatgc
    66181 attggataaa gacttaatag ttgtgttgga tttacaccat tttgaagaaa ttatgaaaga
    66241 accaagagtt cataaagaaa agtttttaaa aatatggcaa cagatagcta ataggtatca
    66301 aaaatatgat aaaaaattgg tatttgaatt attaaatgaa cctaaagaaa atttatattc
    66361 acagttacta aacgaataca ttgaagaagc aataaagata attagaaaaa ctaaccctaa
    66421 aagaactatt atagtaggac catataattt ctatcaaatt gattatttga atgaattaaa
    66481 tattcctaaa gattctaata tagtagtttc ctttcactat tacgagccaa atgattttgc
    66541 atttcaagga aatatatatc ataagggatt tgagcactta agcaatatta cttgggaagg
    66601 aacaaacgaa caaatggatt atttaaaaaa aaggtttgat actgtggaaa attgggcaaa
    66661 taaaaataag gtaaaaatct tcttgggtga atttggaata acaaaagagg caccagaagc
    66721 ttcaagaaga gcatggataa aagctgtaag agaagaagct gaaaaacgaa acttttcatg
    66781 ggcttattgg gagcttgcat ctggatttgg tatatacaat caaattgaag ggacttggga
    66841 tagagatata ttaagtgcat taatagaaaa gaggtgattt tatgaagaaa aattcaaaaa
    66901 agatacttat aactttaact attattacta atgtcatata tatattgtgg agaatttttt
    66961 acacagtacc taaagaagaa gggaagtttg ccttaatatg tgccataata cttctttttg
    67021 tagagataat gggcatgatg gaaatgtttg tgcattatta tggtatgtca aatattgagt
    67081 accctgaaaa accaatcata agtgaagaac tttatccaca tgtagatgta ttcattgcaa
    67141 catataatga atctgttgat ttggtgagaa aaactgtaaa tgggtgtatt catatgcagt
    67201 atccagataa gaaaaaggta catatataca tatgtgatga tggaaatcgt gaagaaatgt
    67261 gtattctagc agaaaaaatg ggtgtaaatt acataactag aactgaaaga gaaggagcaa
    67321 aagctggaaa tttaaataat gcaatgcaac atacaaattc ccctttgatt gctacatttg
    67381 atgcagatat gataccaatg catgactttt taattgctac agtaccatac tttttgaaaa
    67441 atgagcaagc taaaaaagat ggagaaaaag aggagtatga aaaggttggt tttgtgcaaa
    67501 ctccacagag tttttataat ccagacttgt ttcaatttaa tctgcactct gaaggaagga
    67561 ttccaaatga gcaagattat ttttacagag acattcaatt ggctagaaat aggacaaatt
    67621 ctgtaattta tggtggtagt aatacagtta tttcaaggga agcacttgaa gaagttgatg
    67681 gattttatac ttattctatt acagaagatt ttgcaacagg tatcttaatt caaagtaagg
    67741 ggtatagatg ttatgctatt ccagaagtac atgcatcagg tttatctcct acagatttaa
    67801 aaagtcttat taagcaacgt gaaagatggg cacgtggatg tatacaaact ggtagacgtc
    67861 taaatatttt gtttaggaga ggtttaggtt tttggcagaa aataagttat atttcttcaa
    67921 ttacttattg gtatgcaagt ataaaacgct ttgtatatat aatggcacct attttatttt
    67981 ctgtgtttaa tgtgattgta gtaaaatgta cgttacttca agtattggta ttttggttgc
    68041 caatgtatat tttaagtagt ttatctctta aaatattttc tcaaaatata agaaatacta
    68101 gatggaccaa tatatatgaa actataatgt ttcagtcttt aatgccagca gtaatacttg
    68161 aaacgtttgc aatatctaaa aataaatttt cagtaacaaa taagagtaaa ttagaagaaa
    68221 atagaatgta taagttttta cagggaatac cttattttat ttacatggtc ttatctatca
    68281 taggaatttt aaaaatgttt gtagcaatat ttaaaatgag ttcaatgaca tattcagttg
    68341 tattattttg gttgattgga aaccttttta accttgttat ggctacatta tttatatcag
    68401 ggagacagca gttaagaaag tctgagcgtt atattgctga aattgatttt aagttaaagc
    68461 aaaattctta tgttctttct tcaaaaacaa ttgatatatc agaaaatggg tttgcatttt
    68521 tgctagaaaa tccagaatat atttccccag aagaagagtt tgaggtagag tttagagaaa
    68581 aatctggaaa tgaaatgtat atagctaata tgaaagcaaa gattgttaat gttgtggaag
    68641 taaattcaaa gtggaaatat gcagcttata ttacacatat tgaagatagt gaaatagata
    68701 attggatgtg tattgttcac gatagaatac ctactttacc aatgacaata tctaatcaac
    68761 taggtttctt tgatgatttg caaattaatg taaaaaaacg tattgaaaaa actagaacat
    68821 tatcacgaag aagtccaaga atcaatatga attttcagat ggatataaaa aatacaggta
    68881 aattaagaat agtgaatttt aattatcaat atgtattatt aaattttgag aataaaagta
    68941 tttatcctaa agaaatagca ttggaaatta atgaaaatat tgtgttagaa tgtgatttgt
    69001 gtgagggtaa aattgatgaa agaggtatct tatataaagt aaataacatt gacagcataa
    69061 tgcaaaattt ctttttaaga gatgaaatga tggattggat attacaaaat aagaaaattc
    69121 ttgattcaaa gcctagtgaa aagaaggaaa aaagtataga tgagtttgaa cccatggaat
    69181 atatttagga gagatgaaat gaagacttta aaagtgtttt tttgttctac aaaatatctt
    69241 attttggtgt ttattttttt tataaatact acttttataa gttcagcaac aagtgataaa
    69301 attttagatt tatcctttaa aaagatagag actgacttaa gttctaagat tacatatgag
    69361 gatacaggtg taaaaataga aacggatagt tctaaaagcg ataaggaacg ttatttatat
    69421 atttaccaaa atataaaaga aaattggagc atgtataata atttttatat tgaaattcaa
    69481 aataaaaa
//
LOCUS       DAEPHU010000012        66720 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 01A10CD0081
            SAMN05941466-rid12468953.denovo.012, whole genome shotgun sequence.
ACCESSION   DAEPHU010000012 DAEPHU010000000
VERSION     DAEPHU010000012.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941466
            Sequence Read Archive: SRR6291087
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 66720)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 66720)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068158.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 22:43:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,892
            CDSs (total)                      :: 3,805
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 87
            rRNAs                             :: 8, 1, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 55
            CDSs (without protein)            :: 55
            Pseudo Genes (ambiguous residues) :: 0 of 55
            Pseudo Genes (frameshifted)       :: 21 of 55
            Pseudo Genes (incomplete)         :: 28 of 55
            Pseudo Genes (internal stop)      :: 16 of 55
            Pseudo Genes (multiple problems)  :: 8 of 55
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..66720
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941466-rid12468953.denovo.012"
                     /strain="01A10CD0081"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            <1..591
                     /locus_tag="KR231_000840"
     CDS             <1..591
                     /locus_tag="KR231_000840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0003246.1"
                     /translation="IKTFDQSVRKLDKQFNILNIKFVKLFDKYDNQDNINKEILFDIK
                     ESSKNIYNATESQFKIRDYIKNINAGFALYERSAQDLLTKLMTHENKISQNQKILLDE
                     KFTLDDSIKNLSSIIENFSNDLQVKLDMMFENSLDIQDKLDVMFNNSFMNDEVPLDSE
                     ELFKDDVNNVFNPFSEEIYEIEDKEIKVIGEDELNE"
     gene            584..1216
                     /locus_tag="KR231_000841"
     CDS             584..1216
                     /locus_tag="KR231_000841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="OmpA family protein"
                     /protein_id="HBH0003247.1"
                     /translation="MNNKYRRTVNREFEKSSFWPTFTDLLSTVLMVVILILFSSESIS
                     GSVEQDLAKNVNASVEETFKKSGIPVKVDKSNGQVTFGEKTMFDVDSDVLKPEAKEML
                     KMFVPKYIETIYKDYGDYISKIVIEGHTDDVGSYIYNLDLSQRRAYSVAKFIVGDEIG
                     DYKYKDKVTKHIIAIGRSKAELIKNGDNSVNRDASRRVELKYEININQNK"
     gene            1545..2702
                     /locus_tag="KR231_000842"
     CDS             1545..2702
                     /locus_tag="KR231_000842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435380.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HBH0003248.1"
                     /translation="MIEISIKNKKNSKIKTLILLLIVSISIYLTGCTTLDNGNNQSNN
                     NDSLSSSISSDKNVKIHFIDTGNSDAILIQDGKTFILIDGGDNDDEGLMVDYLNNQGV
                     KDIKYLIATHSHADHLGGLDSVVKNFNIENVFVSNGSAETKSYRDFINALANKGLSPS
                     VPLENNKFYLEDSYFEVLNTNGGDTTNEQSLVLVYTNGNDKVLFTGDAEEGTEKEILP
                     KLEKVDLLKVAHHGSRSSSSQEFLDKVNPEYAVLLVGKGNSYGHPHQETMNKLKKMGV
                     KVHRSDECSDIIFESTGDGVFTSCKDGSYNKGVREDGNSGKSNSNTSKNDSFKNKQNT
                     SNSEEIVYFTPKGKSYHSTKNCSGLSRSKKILSGTIAESKKNDPCDICYGK"
     gene            complement(2849..3484)
                     /gene="lexA"
                     /locus_tag="KR231_000843"
     CDS             complement(2849..3484)
                     /gene="lexA"
                     /locus_tag="KR231_000843"
                     /EC_number="3.4.21.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor LexA"
                     /protein_id="HBH0003249.1"
                     /translation="MYLDLTEKQVLILEFIKSQIILKGYPPAVREICTAVGLRSTSTV
                     HSHLNKLEKLGYIRKDPTKPRAIEVLERSKVNDVSGANQEIIELPLVGQITAGEPILA
                     QQNIEEYIPFPASLVKGSNNFVLRVKGESMINAGILDEDYVVVDKKNTALNSQIVVAL
                     INGESATVKRFFKEGNLIRLQPENDFMEPIMLNDSEVEIVGIVTGVFRVIK"
     gene            complement(3588..4715)
                     /locus_tag="KR231_000844"
     CDS             complement(3588..4715)
                     /locus_tag="KR231_000844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HBH0003250.1"
                     /translation="MNNDKKIIKVHNKSDKPDNIVIKENELIEKCLLLENKLPVFMKD
                     YFIYLKGSVAVSTRLAYLEDINFFCSYLIETKELTNADCVKDITEDDFNTIKSRDINL
                     FLGDYCSRYYKNTEKNTLIFENNNRALARKKSSISTLFKFLYRNSQIDNNITDGFNPI
                     KLPKPQPDAIKRLEIDEVAKMLESVETGEGLTEKEKVYWRKTKLRDKAILALFVTYGL
                     RLNELRELNISSFNFSRGEFKIYRKRGKEVLMPINHTCEHVIKDYLQNERTRDELLND
                     EEKDALFLSLQNKRITAKAIRTLVKKYTSIPLDTTRDNGYSPHKLRATAATSLIQTGF
                     SIYDVQNLLDHDNVTTTQLYAAHKKNVKRDIVKNFEWIEDD"
     gene            complement(5036..5881)
                     /locus_tag="KR231_000845"
     CDS             complement(5036..5881)
                     /locus_tag="KR231_000845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0003251.1"
                     /translation="MIYIIEILKISVINIFCFIGIFIVFGLIFSITENLNNKFIFSSF
                     GKTGIIVTGAIGTFVHELSHLIMCLIFMHKINSVKFFRPIESKNDGILGYVSHSYKKD
                     NLYQSIGNFFIGIAPIIGGTIMIILIFKILLPDSYMKVTQNIDLKLYVSMINNLNING
                     FIHIILGDISNFIRIMLLTPSVYSLKYFIFMFLMYSISTHMSLSSADLKNSLNGLSFI
                     VIVIFVISSITYLFGFDNLNISSLIVKYNIFISFFMAIGFIFSIVTLIISYILSLVSP
                     FKNFS"
     gene            complement(5911..6282)
                     /locus_tag="KR231_000846"
     CDS             complement(5911..6282)
                     /locus_tag="KR231_000846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACT domain-containing protein"
                     /protein_id="HBH0003252.1"
                     /translation="MKLKLLVEEYAVCRLNNDSKIPTWIDTEKFYSITRTDDELSVVC
                     LNNNIPSDVKSEKEWRILKILGPLDFSLVGILSKLSSLLADNKISIFAISTYDTDYIL
                     VKEKDIENACKILSCNGYEVE"
     gene            complement(6435..6695)
                     /locus_tag="KR231_000847"
     CDS             complement(6435..6695)
                     /locus_tag="KR231_000847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003866776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage V sporulation protein S"
                     /protein_id="HBH0003253.1"
                     /translation="MEVLKVSSKSNPNSVAGALAGVLRERGVAEIQAIGAGALNQAIK
                     SIAIARGFVAPSGMDLVCIPAFTDIEIEGDKKTAIKLIIEPR"
     gene            complement(6884..7828)
                     /locus_tag="KR231_000848"
     CDS             complement(6884..7828)
                     /locus_tag="KR231_000848"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424062.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyltransferase
                     subunit alpha"
                     /protein_id="HBH0003254.1"
                     /translation="MIENNSEKIKVLENDIKQLITISKANNIDLSDKINSLNEKLEKL
                     KEDAFSHLSAYEKVTLSRDIKRPTTLEYIEHICSNFLELHGDRLFKDDPSMVGGIGQI
                     GKFNVTIVGHQKGRDTKENIKRNFGMPHPEGYRKALRLMKQAEKFNRPIITFIDTSGA
                     FCGLEAEERGQGEAIARNLLEMSKLSVPVITFVIGEGGSGGALGIGVGNDVCMLEHSV
                     YSVISPEGLSSILFKDSSKAKEACDVMKLTSNDLYDLKIIDKIIKEPLGGAQKDVEAV
                     SKEIKAYILERLNHYKDMDKEEIIAQRYKKFRNIGKCL"
     gene            complement(7849..8703)
                     /locus_tag="KR231_000849"
     CDS             complement(7849..8703)
                     /locus_tag="KR231_000849"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyltransferase
                     subunit beta"
                     /protein_id="HBH0003255.1"
                     /translation="MIKKFLSSKESKYVTISLDDNFKKNSVDDKFWTYCKGCDSHVFR
                     KDIEENSFVCPKCSRHYGLRARKRINLLIDKGTFMEFNSDVEFQNPLNFPKYKEKVDS
                     YKEKTKESEAVVTGYGRINGIKTVICVMNPDFMMGSMGSIVGEKITYSIEYAAENNLP
                     IIICSASGGARMQEGMVSLMQMAKTSQALSKLEEKLLPYISVLTDPTTGGVTASFAML
                     GDIIISEPNTLIGFAGPRVIEQTINQKLPEGFQTSEFLLEKGFIDMIVDRRKMKEVLY
                     QILAMHKK"
     gene            complement(8718..10079)
                     /gene="accC"
                     /locus_tag="KR231_000850"
     CDS             complement(8718..10079)
                     /gene="accC"
                     /locus_tag="KR231_000850"
                     /EC_number="6.3.4.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxylase
                     subunit"
                     /protein_id="HBH0003256.1"
                     /translation="MIKKILVANRGDIAVRIIRTCKELGIKTVAIYSEIDKDCFHRYI
                     ADESICIGPNNISKSYNNIENIIYLALKLKCDAIHPGFGFLSENPEFAKQCEDNNIIF
                     IGPTREQMILMGDKSRARETMMELNIPVVPGSESVLKTKEEALEVAREIGYPVMIKAS
                     SGGGGKGMRIVRKEEELFSNFDMASSEALAAFSNSDLYMEKFIENPRHIEVQVFGDKH
                     SNAIHLGDRDCSMQRRNQKVIEESLSPYLSDEERQKLHKIAVDIVKGVGYIGAGTIEF
                     IVDKDKNFYFIEMNTRIQVEHPVTEMVTNLDLIKLQISIANGDKIPFKQEDITFRGHA
                     IECRINAEDSSKNFAPSPGKIESLNLPGGFGVRFDTFVYAGYTIPPLYDSMIGKLICW
                     AETREECISRIYRALDEIIVEGINTNVEFQKALVTSEEFREDTHHTKFIEDVFMKKEF
                     ATL"
     gene            complement(10095..10547)
                     /gene="accB"
                     /locus_tag="KR231_000851"
     CDS             complement(10095..10547)
                     /gene="accB"
                     /locus_tag="KR231_000851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxyl carrier
                     protein"
                     /protein_id="HBH0003257.1"
                     /translation="MNINEIKELLKAIDSTNLEYVKLESSDLRLEVSKKAQSTSSPVL
                     SVQQESVVDLSLEKPVVNDTPVTSNENLSVVVAPLMGTFYDSPSPDADSFVKVGDVVE
                     EGDTLCILEAMKLMNEITSEIKGEIIEVLVSNEELVEYNQPLFKIKPL"
     gene            complement(10817..11263)
                     /locus_tag="KR231_000852"
     CDS             complement(10817..11263)
                     /locus_tag="KR231_000852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0003258.1"
                     /translation="MESKFFNWYTQSLGGTFGIISCICAYLNGYMFVYTNSASKYFES
                     IGFLGIISSYTLLPLCMLTLIFGVIYSYTPETSDKSIFNIPFFTLNKRLILITVVFGF
                     IGARVYFIIPAILITFNLYSNVLIAKLKYILCKNKENDTNLKESEV"
     gene            11538..11816
                     /locus_tag="KR231_000853"
     CDS             11538..11816
                     /locus_tag="KR231_000853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0003259.1"
                     /translation="MVDTLEFGLKILFFILSIIWMGKIMILRTDKQIVINPLLIGISA
                     VLVMLHTSQSNIEFFGLDVQYIRIVLYIIYSLIILIGIWATNRRNGIF"
     gene            complement(11945..12691)
                     /locus_tag="KR231_000854"
     CDS             complement(11945..12691)
                     /locus_tag="KR231_000854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0003260.1"
                     /translation="MWEGTMNLANLIPFIISAAALSPINSNDKVLSENQLKDIFPDAN
                     LRAVVKRYINPDEMTISNIKALDGEFYATGESISNLKGISYLENVDNFIFWNNNIKEI
                     PKEALSLKDMDSINLANNYLIDDDVVNSLSHNGVDVNCDLNFIDTKDNQYKLDSKYHN
                     VDIAKGESIDLRKIITKKIDSYYKYWEVTDNLPKDLNFIVSVSDKSVLSCEDMIIKGN
                     KTGQAVVKVILSDKNDLNTSQEVLITVNVK"
     gene            complement(12820..13464)
                     /gene="trmB"
                     /locus_tag="KR231_000855"
     CDS             complement(12820..13464)
                     /gene="trmB"
                     /locus_tag="KR231_000855"
                     /EC_number="2.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889910.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(46)-N7)-methyltransferase TrmB"
                     /protein_id="HBH0003261.1"
                     /translation="MRRRRKKGADEKLLSYTKYVLRDDIDKLKGKWNLKFRNDNPIHV
                     EFGTGKGKFITTLAKQNPDINYIAMELKEEVLLKAVEKADASNLNNILFLWGDVSNIL
                     DYFEAKELSRIYINFCDPWPKNRWSKRRLTHSGFLEMYNRVLEDDGEIHFKTDNEKLF
                     EFSLNEIAANNWLLKNISLDLGNSEYENNVTTEYEDKFMSQGMRIFRCEAKKRN"
     gene            complement(13602..13922)
                     /locus_tag="KR231_000856"
     CDS             complement(13602..13922)
                     /locus_tag="KR231_000856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein HesB"
                     /protein_id="HBH0003262.1"
                     /translation="MKITLPETAIDTLKSILKDNQDKPNNIRVYFAGVGCGGPSFGLA
                     LDEKKEDDLTYEVGELQFVMSSDEYSQYGDIIIEDTGFGFRVIPENMKDQGGGGCSGC
                     SGCH"
     gene            complement(14375..14623)
                     /locus_tag="KR231_000857"
     CDS             complement(14375..14623)
                     /locus_tag="KR231_000857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HBH0003263.1"
                     /translation="MQKTKAWGIIEPEKPESQQQMAHMDFAVNDLEEAVQYAIHCGAT
                     IAEEQFTDDWRVMIDPAGHPFCLCQMKSIMESSHFSLL"
     gene            complement(14654..15115)
                     /locus_tag="KR231_000858"
     CDS             complement(14654..15115)
                     /locus_tag="KR231_000858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glyoxalase/bleomycin resistance/dioxygenase
                     family protein"
                     /protein_id="HBH0003264.1"
                     /translation="MKFGGVLLIVKDINKSKKFYEDVMEQKITLDLGEHVSFENGFGL
                     QSNYKAIIGYDLPIYQQSNNFQLYFEVNDIKQWESKINRIGNIEFLHYIKEYPWGQRT
                     FRFYDFDKNIIEISESMESVIKRLLKQGLALEEISKRTMYPVEFITQFQQL"
     gene            complement(15153..15986)
                     /locus_tag="KR231_000859"
     CDS             complement(15153..15986)
                     /locus_tag="KR231_000859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBH0003265.1"
                     /translation="MLKKESIHFINKNRSLIVCEDNFVYLLPCIQLRNWISNFTISFP
                     NQTIISDNYTIIPHGSVTLVFFYDATGLHSLLFGPTTKPKTVGNIANRCDVILIIEFQ
                     PAGFFPLIGIQQSELIDKVVPFSIINTSLDLEIKKIFNESLSIDKLILKLEELLISNI
                     KIEYSYEFILAIQLIIQNSGNISSQEISKKVFYSSRHLNRLFNQYLGLSMKSFSRLVR
                     INKSIKLLNNNKTSLMSICNELGFYDIPHFIKDFKIVCGITPQKYRANMSDFYSEIAK
                     F"
     gene            complement(16260..16946)
                     /locus_tag="KR231_000860"
     CDS             complement(16260..16946)
                     /locus_tag="KR231_000860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH0003266.1"
                     /translation="MKITHNSLAVEAKNIIKEYKIGNTTTRVLKEVSLQVMKGEFVSI
                     MGQSGSGKSTLLYILGGLDTPTSGKVYMNGADISHFNDEKMSIIRRRNIGFVFQFYNL
                     IPNLNVEENIMLPLLLDGKNLKDYKNQLDEILDIVGLTDRRKHTPRELSGGQQQRVAI
                     ARALIGKPEILFADEPTGNLDSKTGIEIIDLLNKINRDNGQTIIMVTHSPEAAKSSSR
                     TITVSDGLIV"
     gene            complement(16961..19438)
                     /locus_tag="KR231_000861"
     CDS             complement(16961..19438)
                     /locus_tag="KR231_000861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HBH0003267.1"
                     /translation="MKIILKYIFTNIKERKIRTAVMLLSIVLSTVLLFVSFSIGLSYE
                     SAQRKMAKGMYGTATISVQSKNPDILTNLEDIPDLNAIKSKVGVLESSAIYNKGGYYE
                     EFSLISADLSQLNKINKPRLENGDSITDFSGDKIILPNRFTSKYKIKKGDSITLQIYG
                     KSYTFQVSDIASYDTVFLRNTRGVNALLPKETLSKIINKGSGYTRVLIESEEEITENL
                     VNKLSKELSTEKYMVSNTINETKIISDARQKTMPFFLISFFALTLSIFIIYSSYKVIT
                     LERLPFIGTFRSIGANEKTVTRILMLESILYGSIGGLIAIPIGVVVLNLMLHGLGNSL
                     EQGISIPVVISPIGVIISVIVAIIVSSFSAYIPVKKASHLPIKNIVLGTVEEKNVSNR
                     SILFIGSIMFILSILLPRISPENTLYLAGGFSLLGLIVATIVLIPLITDIMSIVFEFV
                     YKNILGNEGKLAARNMKNNKNIIQNITLLFISISAVIAISVVGNFVKTYITDVFRDAE
                     LQGFADGKMNEEFIEDVRHMDGIKKILPLYVMNNEISGNGVTLSRLEGTDNIKLYNSM
                     FGINYTNFEIKKQVIEAFNDKRSVILNEDTLKKVGLSIGDTITLSNDKYDFSYKIVGS
                     FKSRANDVEAVIPSHYAVNDFDKTNYGFLVYTAVNPDAVMIQIRYLFGDTYNWSRTVE
                     EFNNDSLNTISSFLSPMNKMTYFIFLLATVGIINNLLINYIQKRRSIAMYKSIGLSNK
                     QNIKVTLIEGFTSGLLGAVIGIVISILEIQTIFIVAGPKISMKPDLDFKTFIIVGLLG
                     IIVTLIGSIVPIIKGKKMKLIEEIKFE"
     gene            complement(19657..21060)
                     /locus_tag="KR231_000862"
     CDS             complement(19657..21060)
                     /locus_tag="KR231_000862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBH0003268.1"
                     /translation="MHKPSYKTVFHSYIIFFMIFICLILTVIGIFLSLITIQKPNGEF
                     IRSDWPKKFTENFNEQIVFIDNKPQVKQSGLEKLRENQLWLQILDSSGNRVYGFLEPK
                     EHKDYYSNSELLALANQNNSSNGTVYFNTIKNNKNDYIYIIYFPLNISKVNMFFDGGK
                     FIGGKSIVFSIIGIIFLIILVSGIAYGYWVTKCISNITSAVSDISKRSYLPVNIKGVF
                     ADIYNSLNILNEEIHRSDEIQNKTDIMREEWISNITHDLKTPLSPIKGYAELLTDSST
                     NYSPEKVYKYASIMLKNIEYTNTLINDLKLTYQLKNGIIPLNKNNYDLVRFLKELSID
                     ILNYPEYESNIVEFKSNIDNINFDFDCTLLKRAFSNLIVNAFTYGDKNTKVCVHITLN
                     ERIEIIISDNGKGMSREEASNLFNRYYRGSNTKQKIEGTGLGLAITKQIIEVHGGNIS
                     VESIPGLGSSFYITFPI"
     gene            21553..22413
                     /locus_tag="KR231_000863"
     CDS             21553..22413
                     /locus_tag="KR231_000863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HBH0003269.1"
                     /translation="MKKQKSPILLEMLGLFFGCISMSIGINMFLKPHTIAPGGLSGLS
                     LVLNKVTGLPVSAIMLIIGVPLVILAFRIMGTKNSLKTLFGTVVFSAIVQLTDPLSKL
                     RFTNDLLLSSIAGGILVGIGLGIMFKSDASTGGTDLIALILSKKFPGIKATKFMSCLD
                     GMVVISSGIVNRSLETALYSGIALCVLIKIADMIMEGFDHSKAFFIISDEPESLRQAI
                     TEELDRGLTILDGKGGYTRENKEVLLVVVSKKQELYLKRLVKRTDPTAFVIVTDVHEV
                     LGEGFKNLEN"
     gene            complement(22652..23209)
                     /locus_tag="KR231_000864"
     CDS             complement(22652..23209)
                     /locus_tag="KR231_000864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBH0003270.1"
                     /translation="MSDSEYPQMKTLETRNCILRPASLDDVEDFFDCYKNKIVVKHLP
                     FSEHKSLEDTRKFIKSFFLNPYKKGKIGHFAIVYKRDNKVIGNMGFNNINPKALEAEI
                     GICINPSYWGHDFATEITKRVIQYGFRELNLNKIIAITYEENQNSTKSLDLLGFKCTG
                     KYIKKIHTGNTVKNVPCYQYELKKQ"
     gene            complement(23399..24286)
                     /locus_tag="KR231_000865"
     CDS             complement(23399..24286)
                     /locus_tag="KR231_000865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HBH0003271.1"
                     /translation="MNIKLELYKVFNAVVNNKSFSLAAKELFMSQPAVSQSIKQLEEQ
                     LDTLLFYRNNKGVKLTPEGKILSEHVTTALKLISSGEDRINKFKKLEYGSLKIGVGDT
                     AARFFLLKYLEIFHKKYPHIHVSTINRTSRELISLLKDGNIDIAIINMPIEDDTLNIV
                     ECIEIHDIFVCANDYIEYKGRKISLEELNTLPLIMLENKANSRLYVNEYFLSKGIKLN
                     PDIELGSHELLLEFAYINLGVSCVIEEFSIDYLENEKLFKLDIKEPIPKRNIGYCHLK
                     DISLSLATKEFLSMISNNI"
     gene            24405..25604
                     /locus_tag="KR231_000866"
     CDS             24405..25604
                     /locus_tag="KR231_000866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003493023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="coenzyme F420-0:L-glutamate ligase"
                     /protein_id="HBH0003272.1"
                     /translation="MDRLVGTVSRGVRAPIIRQGDDLVKIVVDSVLNASKSENFEVRD
                     KDVIAVTEAVVARAQGNYAHVDNIAKDVKDKFGDDTVGVIFPILSRNRFAICLKGIAK
                     GCRKVVLMLSYPSDEVGNHLISIDELDDKGINPWSDVLTEEKYRELFGYNKHTFTGVD
                     YVDYYKNLIKDCGAEVEIVFANNPKTILNYTTSILTCDIHTRQRTKRILRQNGAKKVY
                     SLDDIMTASVDGSGYNDQYGLLGSNKATEETVKLFPINCDEVVNKIQGNIKEITGKDV
                     EVMVYGDGAFKDPVGKIWELADPVVSPAYTKGLEGTPNEVKLKYLADNDFADLSGDEL
                     KEAISKYIVEKDNKSDDLTGNMVSQGTTPRRLTDLIGSLADLTSGSGDKGTPIIYIQG
                     YFDNYTK"
     gene            complement(25798..28353)
                     /locus_tag="KR231_000867"
     CDS             complement(25798..28353)
                     /locus_tag="KR231_000867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HBH0003273.1"
                     /translation="MMSLVKFSIQYIKHYKKQSISIVLSIVLSVALLTGIGSLVHSAD
                     KSRIEKIREDSGDYHYFYKVDKEQLNKIKENKKSKEYTVDRLGVTKPKNQIDEPFIIE
                     FLNADSSYLDMTGRKLLKGTLPSKDGEIVLDTYSLNNLNVNKEIGTEINLDGKIYKLC
                     GILSSLSNPETALEGFVNDYFQPKEKDSYIVYVKYDENKNIKKQNYKFMKKFNISKEK
                     TYINWSLSVEFGVKPPKNIEKYNIFEFLKNLELNTNAIILLVGVFGAAAVYSIFHVSI
                     LQRISQYGVLEVLGANNKQLLFLLFLELFLLFIVGFPIGCFLGIGVASTIYEQFPHIF
                     LSSDIVPGAFFISEKSIYLGFLFILLLLILIAVRVVHQLNKYSSIESMKNFKITNKKK
                     RILESVKHSNMTKVLSHKYMTQKKGMFIGILFSLSLGGIIFLCSSYSIQLTKNNNELT
                     MKADDGLNSDYQITMQTTDFDVGIPKDKISRLNNVEGISKVYPVRYLFGAMQIKEEQL
                     FWKNFFKPLEKDYRIKTFFDGICTKQNEGGYLLKTNIYGYNNGMLEGLNSYIIDGEIN
                     THDMVKNNKVIVRLPMDGTGMYDAVDINPGDTIKVKVPKTMKPTDEIVKFKEENKNDY
                     TTKEFVVAATVKRVMANNIYFIGDYGMDIVMTNGQMKNNFDIENYNSVSIKKTEDSNS
                     EELSENIKSVVSDVKRCIVTDYTIAIEKNNTYLNQKLLFIYGIVFVLLAISLFHIINT
                     VSYLIFSRRHEFGILRAMGITDNKFLLMMIREGFLYGFYASIIMVIGSVIGQFMIYFM
                     VKRVYLYINPILKINTPLYIGMIILNITISIVAVIIPVRQILKSDIISEINKN"
     gene            complement(28350..29036)
                     /locus_tag="KR231_000868"
     CDS             complement(28350..29036)
                     /locus_tag="KR231_000868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH0003274.1"
                     /translation="MSILVTNNLVKHYGKGETKVKALNGVSIEIERDTFTAIVGTSGS
                     GKSTLLNIIGGLDNPTSGDVIIKGKNISKIGKKDLTVFRRRNIGFIFQNYSLMPVLNT
                     YDNIALPVTLDKGNHIDHEYIEMLMKTLGIWDKRLKFPSELSGGQQQRVAIARALANK
                     PALILADEPTGNLDSKTTMEVVCLLKESSAKFHQTILMVTHNENIAQVCDSIIHIEDG
                     VVVNTGGELL"
     gene            complement(29113..30021)
                     /locus_tag="KR231_000869"
     CDS             complement(29113..30021)
                     /locus_tag="KR231_000869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435311.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBH0003275.1"
                     /translation="MFILAFIICTVVIFIVSTKINRKRYDELNLMLNQILEGKEVTYP
                     DTKDTRASKISHQVKKIKDMIEIEVEQSKSEKEAIKGLISNMSHQLKTPLSNITIYCE
                     LLENINISTLQKKEFLQKMKNETFKIDWLLQSLFKMTKLEDGVIEFEVEELLIKDTLI
                     QSISTIFNKAEAKNIRINLEPFSDIKLVHNKKWTIEAIVNVLENAIKYSPSDSTITIS
                     VIKMELYTKITIKDEGIGIDSRELNDIFKRFYRSKNVENQNGTGIGLYLTRLILEKEN
                     GNIIVESKLGSGCCFSIFLQNCKSLN"
     gene            complement(30023..30694)
                     /locus_tag="KR231_000870"
     CDS             complement(30023..30694)
                     /locus_tag="KR231_000870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBH0003276.1"
                     /translation="MNLLIIEDDINLNEGLFYAFENDGFNVFKAYTKQEGLNIFNSKN
                     IDFIILDCNLPDGDGFDVCQIIREKSDIPIIMLTARDSEIDEVKGLEIGLDDYITKPF
                     SLSVLKARVKVAIRKKSNNKVIYSNGIKLDQKLLKVYKNKECLELSSVEYKLLSYLIE
                     NKGQILLKEQILHHIWDSEENYVDDNIVSVNIRRLRVKVEDDPSNPKYIKTAYGMGYL
                     WNEVE"
     gene            30956..32020
                     /locus_tag="KR231_000871"
     CDS             30956..32020
                     /locus_tag="KR231_000871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S ferredoxin"
                     /protein_id="HBH0003277.1"
                     /translation="MKRVDERNTMFARANYKKDSTAYNDYYKKNPDKKEIDDSIRNRP
                     NLCSEGTMTYNELNSPMASSAFDFLSDIKSLCEGKVSDTKVDVDAKSMTKKIKGLAKQ
                     YGASVVGITKLKDYHIYTNRGRHEENYGEEINLTHKYAIVFGCEMDKEMINRAPMICE
                     VIETSKCYVDASIVGMILSYYIRNLGYDARNHMDANYLVMPVFIARDAGLGDIGRNAI
                     LTNKDYGSRLRLGVVTTDIPLLEDEYVDFGLEDFCKVCKKCSFNCPSHSLSNDIKIGD
                     DGKYNWVIEHETCYIKWRYLGTDCGMCISACPFSQNLETIKNTTSFKGNNELIQKALD
                     EYTSKFGKRIFIPGNPSWLK"
     gene            32178..32864
                     /locus_tag="KR231_000872"
     CDS             32178..32864
                     /locus_tag="KR231_000872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBH0003278.1"
                     /translation="MEKILVVEDDSILNKTLSYNLIEDGYIITSKFTAKSALKSIFEC
                     EFDLIILDINLPDKSGFELCNEIKENYNIPIIFLTANDMECDMIKGYELGALDYITKP
                     FNINIFKQKIKAFLNHLTIKTKQDYYKDGYLEINFSELSANINGNQIIFTPLEYRTLK
                     LLTENPKSILTRKVLLEKLWDIDANFVDEHTLTSVISRIRSKIEKDNLKYIKTVYGMG
                     YMWLGERNEF"
     gene            32854..33885
                     /locus_tag="KR231_000873"
     CDS             32854..33885
                     /locus_tag="KR231_000873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBH0003279.1"
                     /translation="MNFKKFSFSSIYLIIAVGIIFTAILFSISIYLITGDLKLIALLL
                     IYTMVLCGFIALIIFLLHKKIVIFCSKICHTLDSMMNSEDNIEIELEEETILSRINHR
                     LIRMYEVIQENRNSIAIEKADLQELVSDISHQIKTPIANLKMINTTLLNQTFKTEIQK
                     DFLMDMENQLDKLDFLMQSMVKTSRLETGIITLSKKKNSIYETIATALSGILFDAEKK
                     NIEVTVDCDPNLYIIHDKKWTSEAIFNILDNAVKYTSSNGKIRVATECWVMYTKIDII
                     DNGKGISESRQAEIFKRFYREEDVHDIEGIGIGLYLSRKIISLQGGYIKVTSDIGKGS
                     TFSIFLPNK"
     gene            33967..34632
                     /locus_tag="KR231_000874"
     CDS             33967..34632
                     /locus_tag="KR231_000874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH0003280.1"
                     /translation="MSILQVINLKKYYGQSSNITKALDGVTLSIEKGEFISIVGTSGS
                     GKSTLLNMMGGLDNPTSGKVIIKGKELSTMSDEQLTIFRRRNIGFIFQNYNLVPLLNV
                     YENIILPIGLDGETIDKDFINEIINMLSLEEKLYDIPSNLSGGQQQRVAIARALVTKP
                     AIILADEPTGNLDSRTSSDVLSLLKVTSKKFNQTIVMITHNNEIAQLTDRIIRIEDGK
                     IVN"
     gene            34645..37062
                     /locus_tag="KR231_000875"
     CDS             34645..37062
                     /locus_tag="KR231_000875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBH0003281.1"
                     /translation="MFRNNNRTFIRKIALNDLKINKLKTYLSGIIIMISTCLLLTVTL
                     VSYNASVDLVNASPYHAIYKSVDEKAKNILYKNKNFSGVGTYKLIGSNKKTDCIMSIV
                     YADDTAIKLMNFQPLKGKLPTNKNEIAISEKYLQEFGLDKDIGDSIKLNYYDDITNKE
                     VQCDFIIVGFLENYYQDNAKQYYTVVSNDYFKNIASTPLQNKSNTFDESRPDTVDVLV
                     KLSEENTEKDSASIKTQLNKIGLSLGIKKYNIYLNDNYIESNLIDGEQIITVLVVGIV
                     VLFSSVFVIYSIFYISVVNSVQMYAKLKSLGMTSFQLKKIISLQGNILSIIFIPLGVI
                     ASCIIAYIIQPLAWQMIADLFIILILSLVMFLTVRISLFKPARIISKISAIEAMQYTE
                     TKFRKKAKNFSYINIKNLALKNIESNRKKNLIALISLSISGVLFISIANLANSIDFKK
                     QLSQQFVYNEDYIISIKSDNLYEHITEIQQNNPLTDSLKNEIKSIHGVKKLIESKSIK
                     SNIIEPYIKDRDEKQFITLIKGITPELSKSLEEYIVSGKIDYTHLDSDSLIINKYRTK
                     YYGLNLKVGDTVTFNIFSGNDIIKKKMKIIGIIDNSNTGGMFFASDKTLESLTPYNTN
                     LDFSILIDKKHSKEVEEKLLSIIQKNSNLMLYSYEDDYRMITRAFQYIIIASYIFVGL
                     ISCFGILNMTNTLINSVLIRKKEFALLQAVGMTRKQLRNMLYREGLNISIKAICTSST
                     LGYFGSNLLCTFIKDVIRLDFINFKFSIFTILIFSFVLIGIQVLVTELLVRNIEKKSL
                     TERLRSQ"
     gene            complement(37243..38034)
                     /locus_tag="KR231_000876"
     CDS             complement(37243..38034)
                     /locus_tag="KR231_000876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HBH0003282.1"
                     /translation="METKQYLIDFYNTYDEDSRLALKHGMVEFLTTMHYIDKYIKSGD
                     CVLEIGAATGRYSHTLARQGYDVDAVELVEHNIEVFHKNTQSNENISITQGNAMDLSV
                     FPDNKYDITLLLGPLYHLYNKEDKQQALHEAIRVTKPGGVVFAAYVISDGCLIDEGFH
                     RGNINVSEYIEKGLIDPQTFAAKSEPKDLFELVRKENIDDLMSAFNVTRLHYVASDGL
                     ALYMREAVDSMDDDAFALYLKYHLATCEREDLVGVTSHAIDIFRK"
     gene            complement(38067..38654)
                     /locus_tag="KR231_000877"
     CDS             complement(38067..38654)
                     /locus_tag="KR231_000877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBH0003283.1"
                     /translation="MPPKVKITKEMILNTVLDITREVGFEAVNARSIASKLQCSTRPI
                     FTCYENMNELKNEFLAFAYEYYNQYVVNYSNSKSVSPYLLLPLSYIEFAQEETHLFKL
                     LFINDLDLMMEEANDFYKEIDNEKKARLFSESIGIELECAKVIFLDLFLYTHGIAVLT
                     ATKKLTLDRYSAEKMLKNILTAFIRQEKPDWNLSI"
     gene            complement(38831..40222)
                     /locus_tag="KR231_000878"
     CDS             complement(38831..40222)
                     /locus_tag="KR231_000878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="benzoate/H(+) symporter BenE family transporter"
                     /protein_id="HBH0003284.1"
                     /translation="MERLARREQPHIKFGMFKIRIPFIHYRFEKPEAIQGIISSMTSL
                     GTIGLSTQILGLPYEVAWSMAIINSILYCLHVFMGDPVVPGWITASITLTTAYLLKFS
                     MGIERIQALTALQIDLGIIFILMGITGVAGKLVSKIPNSIKGGILMGVGISTIISEFN
                     PKGRFDSYPISITVGILVACFVMFSERFDTLKVKNKFLFHLGEYGVVSAILVSLIVGI
                     FSKEIEIPRFSFDNLVYIVDFKNLINTVSPFGIGFPSVMLFIQGIPMAFMIYIIAFGD
                     FITGENLVLSESENRKDEYIDFNSNRSNVISGIRNIFMAIFSPYIPMCGPLAATLTGS
                     VAQRYKVGKEAMQSVFSGMGTLVWVSAIFICFYPIAQIATPLIPLALSVTLLVQGYLC
                     TKLSMELCNTGVEKGLIGLMGGVIAAKGGTWGLAVGFILYFILIDSKKRKEKDINSIE
                     DCVYEILDKKKSI"
     gene            complement(40412..41710)
                     /locus_tag="KR231_000879"
     CDS             complement(40412..41710)
                     /locus_tag="KR231_000879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA thioesterase/BAAT N-terminal
                     domain-containing protein"
                     /protein_id="HBH0003285.1"
                     /translation="MKVNVYNVESFVDERLKIMVSDLIPNTKLKISVKMEFPWCKGEE
                     FSSYGVFCSNEKGEVDLDLVEPIEGTYKADNCMGLIYSLEKSKTEGKNFAENISIDKP
                     IIMNMIFETSIERKEVELKRIFKSEDITTKYISDEFIGKLFYKQNSNNKTILMLGGSD
                     GNLDALDLLAAPLASRGFNVLTVAYFALEGLPDKLEEVPLEYFEKVFEWISENEITST
                     KEIFVHGTSKGGELAFLLASRYEQIKKVVVSQPHIYCFQALNGLMSGNDTSSWSYKGE
                     PFPYIKVDNDIFFEEQKKNISKDIPFGFNSTYKKSLKRAENRKEARIKIENSKADILM
                     IAGKEDNIWNSYEACLEALEIFEENNYPYNVELLTYNNMGYPLPIPYIMPLKETLCMS
                     MSRGIFSSGGTVEGNSKGQFESWNRTIEFYKKPLSSDLNN"
     gene            complement(42067..42942)
                     /locus_tag="KR231_000880"
     CDS             complement(42067..42942)
                     /locus_tag="KR231_000880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="kinase"
                     /protein_id="HBH0003286.1"
                     /translation="MITFDVNGAIIRFDDTKNNYNKIRKIFKLYALEISKNFERDCLN
                     SFQNLKQISDRGLSLGEKYIEESFKKGIETIVSFGIITIDIDTFKSVYCEKYLDFKRL
                     FNNLNKTFIIPNKNKKNGHASFLEIESTIKKMSNYLYNDCFKIHYAVVDALIENRITA
                     VHSYIDEESIKKSNALFNNYKDGFIGKADECKVVKQIITLNPYREDVYEFLVKEDGDF
                     SKEIERLTEFLGYDIREYKASLMDIYINELMESDENDVENAKEKIEKYARYIGCSDEN
                     LYVARVNAIYTFANA"
     gene            complement(43135..43821)
                     /locus_tag="KR231_000881"
     CDS             complement(43135..43821)
                     /locus_tag="KR231_000881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF554 domain-containing protein"
                     /protein_id="HBH0003287.1"
                     /translation="MFGVIANSLAIAGGCIVGLIIKGGLPQRVSDTIMNGIALCVLYI
                     GISGALEGKNTLVTIISVAVGALIGELIDIDKWVNKLGAFLQSKFSKGNKKDSIAEGF
                     ISSSLLFCIGAMAVVGSLESGLTGSHDTLFVKSVIDGIASIIFTASLGIGVMFSAISV
                     FLYEGIICVGASFLNGFLSDPVVTEMTAAGSLLIIGLGLNVLKLTNIKVANLLPAIFI
                     PILFGVFGII"
     gene            complement(43870..44403)
                     /locus_tag="KR231_000882"
     CDS             complement(43870..44403)
                     /locus_tag="KR231_000882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolyl-tRNA synthetase associated
                     domain-containing protein"
                     /protein_id="HBH0003288.1"
                     /translation="MSDLNNKKEQDENESSMNETKIYDILDKLNVEYDVVEHEAVYTA
                     EQLVILDGITKGCQCKNLFLRNAKGNKYYLIVVKGEKQVDLNSLKDKIGSSRLSFASP
                     ERLYNVLKLLPGSVNPFSLINDTERKVELYIDKDVIKEDYLNFHPNINTKTVNISRKG
                     FEEFLEYLKYPIQSIDV"
     gene            complement(44447..45079)
                     /locus_tag="KR231_000883"
     CDS             complement(44447..45079)
                     /locus_tag="KR231_000883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cyclase family protein"
                     /protein_id="HBH0003289.1"
                     /translation="MKVFDLTHVTHNDMPVYAEPNRPDIKKVAIIEENGYQETLISVF
                     SHNGTHMDSPRHMYTKGETLDKLDIENFVGKAYVLELEKGNENIELEYLKKYEDEIKN
                     SDFIIFKSGWSKFWDKKQYYVGYPTLTKEAANYIANTNIKGIGIDMLSVDRYDTSVFE
                     VHHILFEKGKIIIENLTNLENVPEKFLFIAAPFKYNDADGAPVRAIAIVE"
     gene            complement(45169..46248)
                     /locus_tag="KR231_000884"
     CDS             complement(45169..46248)
                     /locus_tag="KR231_000884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435274.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIR2 family protein"
                     /protein_id="HBH0003290.1"
                     /translation="MKIAIFLGAGASAAENLPIQNELFSEYFKKLNPTNYNTKMNREL
                     YIFFKQMFNIDIVKDNIDNANFPTFEEVLGLLDLAEQRKEAFRNFGLENLNNRSDSIR
                     FLRQYLILLMAEAIHNTPRTDNKYHKLLVENLLENDLLLDTTFISANYDIHIDNTVTG
                     LRDKNDLPIMLDYGVEFTNFKEELNWRKPKEPLIKLYKIHGSLNWLYCPICNSVTLTP
                     HEGGVMKLIENSSETKCLECGELTEPIIVPPTYFKNMSNIFLSNVWNETEKTLRDTDL
                     LIFCGYSFPEADMHIKYMLKRVQTNRKKPPLKIMVFNNHSQKQRITLKKEEGRYKRFL
                     GEDVIFTDNSFQDFSVNPLRFIKNI"
     gene            complement(46381..47727)
                     /gene="pepV"
                     /locus_tag="KR231_000885"
     CDS             complement(46381..47727)
                     /gene="pepV"
                     /locus_tag="KR231_000885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptidase PepV"
                     /protein_id="HBH0003291.1"
                     /translation="MKEQIKEKVNSLQDEMISSIQESVKIPSVISEATENCPFGENVD
                     KALRGILDLCKSLGFKTVYKDGYYGYAEIGQGEKMIGILGHVDVVPEGDLESWNYPPF
                     EAVLEDGKLYGRGTQDDKGPTISAIYAVKALMDLNVDFNKRIRFIFGADEENLWRCIN
                     KYKENNEEIPNYGFTPDSRFPITNAEKGLLQVHLTCDSKSDIELSVGKALNAVPGKAI
                     YIGKYSDKLKKELDKLNFEYTVEGNKICIIGKSVHSAASDTGINAVARLCIALNNIGI
                     DSNIIKFLAEVIGEDANGNNIIPNCKDDVSGKLTVNIGRVTIDNEKEFAGIDVRIPVT
                     YKKDDFVKELKKMTDKYNLNYEEYDFLDSIYVPEDTLLVKTLRKVYEEETGLDGTPLS
                     SGGATYARALDNCVAFGAIFPGKPETEHQANEYLIVEDIIKATQIYALSIYELLKI"
     gene            complement(47796..49076)
                     /locus_tag="KR231_000886"
     CDS             complement(47796..49076)
                     /locus_tag="KR231_000886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine gamma-lyase family protein"
                     /protein_id="HBH0003292.1"
                     /translation="MLNETKELLKDYYGIDDDTFKLSQEIMEEIKDKFEEIKEIREYN
                     QYKVLKAMQESKLSDMHFNWTTGYGYNDIGREKIEEIYSKVFNTEDALVRPIIVNGTH
                     ALTLCIQGIVRPGDEILSVTGRPYDTLEGVIGIREEKGSLKEYGVTYDDVDFLEDGNL
                     DLEGIKNKINDRTKLVMIQRSKGYSWRKSLSISDIKEAIEVIKSVKPEAIVMVDNCYG
                     EFLDTKEPTDVGADVMAGSLIKNPGGGLALTGGYIAGRKDLIELISYRMTSPGIGKEC
                     GLTFGTTRNVLQGFFLAPYIVSQAVMGAIFCSRAFEKLGYDVLPKYDDLRSDIIQCIR
                     LNNADEVISFCEGIQEAAPVDSYVKPVPWDMPGYESEVIMAAGAFIQGSSIELSADAP
                     IRPPYNVYFQGGLTFDHSKMGTLKAIEFIKKLKK"
     gene            complement(49203..49463)
                     /gene="hfq"
                     /locus_tag="KR231_000887"
     CDS             complement(49203..49463)
                     /gene="hfq"
                     /locus_tag="KR231_000887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA chaperone Hfq"
                     /protein_id="HBH0003293.1"
                     /translation="MKNTVLNLQDLFLNNARKERIPVTIYLVNGVQVKGLVKGFDSYI
                     ILIEGDNRQQNMIYKHAVSTIQPGKYINLTNQNQNNNNNNNR"
     gene            complement(49577..50512)
                     /gene="miaA"
                     /locus_tag="KR231_000888"
     CDS             complement(49577..50512)
                     /gene="miaA"
                     /locus_tag="KR231_000888"
                     /EC_number="2.5.1.75"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenosine(37)-N6)-dimethylallyltransferase
                     MiaA"
                     /protein_id="HBH0003294.1"
                     /translation="MKKIPLIILTGPTAVGKTDLSIKLAKDMNAEIISADSMQIYEYM
                     DIGSAKVTEEEMQGVKHYLIDEVKPDYPFSVSEFQQRAKKYIHEINEKEKCVLVTGGT
                     GLYLNSLIYNMDFAQSDANNELREELQKQLAEKGIDYMHNKLKELDEESANRIHKNNT
                     KRVIRALEVCLSGKKMNDFSSDLKFNEEYQPIIIVLNRDREHLYQRINMRVDIMIKNG
                     LVEEAKKLLSMGFKKDMISMQGIGYKEILKYLDGEYTYEEAIEIIKRDSRRYAKRQIT
                     WFKRYKTAKWFDLDQYENIDELKNEIILYIKDSIK"
     gene            complement(50550..52517)
                     /gene="mutL"
                     /locus_tag="KR231_000889"
     CDS             complement(50550..52517)
                     /gene="mutL"
                     /locus_tag="KR231_000889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair endonuclease MutL"
                     /protein_id="HBH0003295.1"
                     /translation="MKNIINILDDLTINKIAAGEVVERPSSVVKELIENSIDAGANKI
                     SIDIIDGGKSLIKITDNGIGIPSSEVEKSFLRHATSKIKKIDDLYDLYSLGFRGEALA
                     SISAVSKLEMTTKTKDEIIGTKIYVEGGKIISKEPIGSTNGTTIIIKDIFFNTPARQK
                     FLKSTHAETINISDLINKLAIGNPNIQFKYTNNNKQMLNTPGDGKLVNTIRSIYGKEI
                     TENIIDVEFKCNHFKMNGYIGNNNIYRSNKNLQHIYINKRFVKSKIIIDAITESYKSI
                     IPIGKHAVCFLNIEVDPSCIDVNIHPNKLEIKFEKEQEVYIELRDFLKVKLIHSNLIG
                     KYATYSDKKTQPRIAINSREKSTDYKLRNNDLLESTPKNSNITKGKDEVIEVVTLSSE
                     KPINEFQSVSEVLNASVEDDVKNINYLSEDSANDNIQEEFQVDGIKNEGNYYLGDSIK
                     DSEEEYLCSSKRKFSLYGYFVIGVVFNTYIILSKDDSMYLLDQHAAHERILYERYMEK
                     FYRQDINMQILLDPVVIEVSNIDMLQIENNLELFMKFGFELEIFGNNHIMVRCVPTIF
                     GVPETEKFILQIIDNIEEITSNYDLKGERFASMACRSAIKANDKIYDIEIKSLLEQLE
                     KCENPFTCPHGRPIMVEISKTEIEKMFKRIM"
     gene            complement(52528..55371)
                     /gene="mutS"
                     /locus_tag="KR231_000890"
     CDS             complement(52528..55371)
                     /gene="mutS"
                     /locus_tag="KR231_000890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair protein MutS"
                     /protein_id="HBH0003296.1"
                     /translation="MQIDMNKLTPMMKQYLEVKNRYKDCILFFRLGDFYEMFFEDALV
                     ASKALEIALTGKACGLEERAPMCGVPFHSANSYISKLVENGYKVAIGEQMEDPSTAKG
                     IVRREVIRVITPGTVLDGNLLENKKNNYLLSLYKDGTNIGLTYVDISTGETNATCLNE
                     DKVIEEIAKIHPTEIIINDLDFIEKLRDIATVSNIYINESFSDNYLDINILKEYFPDV
                     YLQKLKFDDKGLIKSSLSILLNYIYNTQKQITSNINNINIYNSSEYMVLDMFTRTNLE
                     LTQTIRGNKKKGSLLHVLDKTSTAMGGRLLRKYVEEPLINKSKIENRLDVIEEIKDDF
                     ILREDLNDILKNIYDIERICGKIAFERVTPKELIHLKNSIEKLPNLKDTINLSNAKIL
                     KEYVSEMDKLDDIYNLIDEAILEEPTITIKDGNIIKSDFSDELKELREISKNGAFLVK
                     EIENREREKTGVKSLKIGFNKVFGYYIEITKANFKQAKLDETYIRKQTLSNAERYITP
                     ELKEIEEKILHAEEKIKSLEYEIFVEIRDTIYKNIDRIQKVAKTIANIDVFVSLATVA
                     HINNYVKPAINENNKLDIRNGRHPVVENIVGEENFVPNDTYLNRGENIINIITGPNMS
                     GKSTYMRQTAIIALMAHIGSFVPAESADIPILDRIFTRVGASDDLSQGQSTFMVEMNE
                     VSLILKNATERSLVILDEIGRGTSTYDGISLAWSIVEYIQKNIRCKTLFATHYHELTD
                     LEEEFKEVKNYSIAVKEDGEGIIFLRKIIPQGADKSYGIYVAKLAKLPDEVIERAKYI
                     LKDLEKNHVYNSVAINGDKENNNIINSNLDEELVKVNQSNFKNKYESLKIEHELIVKD
                     YKHIKKDYDKLNSKFKALNDEVALMKQNDDKEKINQEDSVKEVALTQISFDSVNRDIL
                     SEEILNLDILNMTPLDAINSLYNLQRKAKEIKS"
     gene            complement(55532..56266)
                     /locus_tag="KR231_000891"
     CDS             complement(55532..56266)
                     /locus_tag="KR231_000891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH0003297.1"
                     /translation="MLTQMNFYHNKKVKVSIENVSKTYKDIEVLKDISIDVYEGEFVS
                     ILGPSGCGKSTIFNIITKLTDYDSGKVNINGKYSYMYQKDLLLPYKTIIDNVSLPLIL
                     KKEKKSKARSMVKPYFEVFGLSGYEDKYPSELSGGMRQRANFLRTFINSNDIMLLDEP
                     FGALDSLTKTSMQKWLLDVKKKVNSTILLITHDIDEAIMLSNRIYVISKKPSIVKKEF
                     VIDSRKLNEDNLENIIKLKKEIISLL"
     gene            complement(56235..57248)
                     /locus_tag="KR231_000892"
     CDS             complement(56235..57248)
                     /locus_tag="KR231_000892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HBH0003298.1"
                     /translation="MNFKKLGILGLVSVFTLATITGCSSNNNKDKNNDKDTSSKKVTM
                     VLDWTPNTNHTGLFVALDKGYYKEEGLDVEIVQPPESGAETLVATGKADFGISYQEQV
                     TYAKTSEDPLPIKAVATVIQHNTSGFASPKEKNITTAKDFEGKTYGGWGSPSEEAVFK
                     AVMKKNGADFNKLKIVNTGQDDFFAAMKTVDFAWIFEGWDAVKADLIGYDLNFIPVKD
                     LDERLDYYTPLIISNETVLKNNPELAKKFLKATTKGYEYAIKNPEESAKILVKHAPEV
                     DEKLALKSQEYLASKYKDDAPRWGEMKDSVWNNYTSFLKEYKLIDKDMKASDAYTNEF
                     LPQ"
     gene            complement(57270..58040)
                     /locus_tag="KR231_000893"
     CDS             complement(57270..58040)
                     /locus_tag="KR231_000893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBH0003299.1"
                     /translation="MKNLEIIDKVKDSIYPIATFLFILILWQSMVGVLEVPQYILPTP
                     VDIINVFFKDYQNLSIHAVVTIGEAILGFIVAIIISLVIGILMDFVSIIKKCLYPIML
                     VTQMIPTIIIAPLFMIWFGFGTMPKVLMVMLTCFFPILISFVDGIENIDKDYLNLFKT
                     MDSNKVNTFIHLKFPMAMDKFFSGLKISATYAVMAATVAEWLGGTKGLGVYMLRSKSA
                     YALDKVFASTILVVIFSLMFVGIVQAVKKVVIRHRLID"
     gene            complement(58015..58305)
                     /locus_tag="KR231_000894"
     CDS             complement(58015..58305)
                     /locus_tag="KR231_000894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MTH1187 family thiamine-binding protein"
                     /protein_id="HBH0003300.1"
                     /translation="MVIADIAVMPLRPYKGEEEMYKVVDACIAEIEKSGLKCEIGAMS
                     TTVEGDFDEVFELLKKVHKIPFNLGCERVITVARVDEKAGGLTIDEKLRNHR"
     regulatory      complement(58436..58535)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     regulatory      59155..59244
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01051"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="cyclic di-GMP riboswitch class I; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="cyclic di-GMP"
                     /db_xref="RFAM:RF01051"
     gene            59297..59473
                     /locus_tag="KR231_000895"
     CDS             59297..59473
                     /locus_tag="KR231_000895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0003301.1"
                     /translation="MFMDKMDRCTHILTAYICSSRDYCNFIDTQLNDFILEYGENVVE
                     SCLHQVMVLVSRYN"
     gene            complement(59588..59944)
                     /locus_tag="KR231_000896"
     CDS             complement(59588..59944)
                     /locus_tag="KR231_000896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428797.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBH0003302.1"
                     /translation="MDIDNNFEEFPNIEERQKDFNCSIGFTMTVIGSKWRAIILWHIL
                     KQEPIRYSQLKKEVVHISHKILSQELKYLERDGLIKRISYPTIPPKVEYLSTKRGKSL
                     ESILLELCNWGKQYMR"
     gene            60200..61113
                     /locus_tag="KR231_000897"
                     /pseudo
     CDS             60200..61113
                     /locus_tag="KR231_000897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007061260.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PhzF family isomerase"
     gene            61344..61955
                     /locus_tag="KR231_000898"
     CDS             61344..61955
                     /locus_tag="KR231_000898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA pyrophosphatase"
                     /protein_id="HBH0003303.1"
                     /translation="MINDIKNKFKNYKPYINGYKNMKRASVLIPIVEINNTHYILFEV
                     RSKNLKHQPSEISFPGGKIESGETPYEAVIRETCEELGTFSDNIEVISSLDLLITPVK
                     FIIHPYLGYIKNINNLNINKDEVDHTFLVPIKYLLENPPNTYSNTVKVFPDENLPYGS
                     IPNQKDYKFESGSYPILFYKYKDYVIWGMTAKILENFLNFLSE"
     gene            62253..62591
                     /locus_tag="KR231_000899"
     CDS             62253..62591
                     /locus_tag="KR231_000899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3784 domain-containing protein"
                     /protein_id="HBH0003304.1"
                     /translation="MFAVGFVVIIALAFFILSVLLFNGKASMLLAGYNSMSKKEKARY
                     DKKKLCRSSSIVTFIVSIMLFIMAFLGYRIESGQMDEKKMVPFSIIFIIVILSSVFFN
                     ILYSNKKCKK"
     gene            complement(62998..64434)
                     /gene="miaB"
                     /locus_tag="KR231_000900"
     CDS             complement(62998..64434)
                     /gene="miaB"
                     /locus_tag="KR231_000900"
                     /EC_number="2.8.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (N6-isopentenyl
                     adenosine(37)-C2)-methylthiotransferase MiaB"
                     /protein_id="HBH0003305.1"
                     /translation="MSKRKQVTIPIEKIQEQDKYIEQIHRQNEEYFNRTGKRKLVFTQ
                     TFGCQMNEHDSEKLCSMLEEMGYQMSMMVEESDLIIYNTCAVRENAELKVYGNLGQLK
                     HLKGKNPDMKIAVCGCMMQQPHVVEELRKKYKHVDLIFGTHNLYKFPQLLTESINSDK
                     MLVDVWDVDGEVIEGLRSNRKFELKAFVNIMYGCNNFCTYCIVPYTRGRERSRTPEDI
                     INEIKELVANGTKEITLLGQNVDSYGKTLENPVSFSELLRKVNDIEGIERVRFMTSHP
                     KDISDEVIYAIRDCDKVCEFLHLPIQCGSSSLLKKMNRHYTKEYYLEIIEKAKKEVPG
                     IAFSTDLMIGFPGETEEDLLDTLDVVEKVRYDSAFTFIYSKRQGTPAAKMENQIPEDI
                     KHDRFNRVLEAVNRISAEINDGYKDRIVEVLVEGRSKNNENKFAGRTRQNKLVNFEGG
                     NDDLIGKLVMVKITEPRTFSLNGILVNN"
     gene            complement(64682..66142)
                     /locus_tag="KR231_000901"
     CDS             complement(64682..66142)
                     /locus_tag="KR231_000901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp28"
                     /protein_id="HBH0003306.1"
                     /translation="MKFYKRILTLTLSISFVFANIQLVDAISSVEKIQGKNKYEIAGK
                     IADKNAYKTAYKTAYKTAILINTSNSIADGLSASGLAGALNAPILLTEKNTIPTETSA
                     RLKNVSKVYIIGGTYSISTSVENSLKSKKMKVVRIKGNDRIKTSYNVAKEINSIKKVN
                     TVMLTNAYKGEADAISIASVAARDKAPIILTNGQSIPFSTSGLKSYVIGGTASMSTTL
                     VNNTKSTRLGGSTRFETNKAIINKFYKDAREFYIAGAYELTNALVGSSLSKHGPMVLV
                     NDGSNKSILKNAKKITSIGYIDSNIVQQCLNITNGIGDINTGVVKNVKPTTKTIKDGM
                     YKVGKDISAGEYLITSNSGSYASYYEVTSDSTGNADSILSNDIFSGTRYITLKNGQYI
                     KIEDSTMTLAKYAKAQKAKNGKFGNGMYKIGLEIPAGEYIIMSNSSDAYYEVRNDSLG
                     NAEGIVTNDTFSGRRYITVEEDQYLILNDCYLIENE"
BASE COUNT        22949 a        10273 c         7658 g        25840 t
ORIGIN      
        1 attaagacat ttgaccagag cgtaagaaaa ttagataaac agtttaatat tttaaatata
       61 aaatttgtaa agctttttga taaatatgat aatcaagata atataaataa agagatttta
      121 tttgatataa aagaatcttc aaaaaatata tacaatgcca ctgaaagcca attcaaaatt
      181 agagattata taaaaaatat aaatgcagga tttgctctat atgaaagaag tgctcaagat
      241 ttattaacta aattaatgac ccatgaaaat aaaatctctc aaaatcaaaa aatcctttta
      301 gatgaaaagt ttaccttaga tgactcaata aaaaatctct caagtattat tgaaaacttt
      361 tctaatgacc tacaagttaa actggatatg atgtttgaaa attctttaga tattcaagat
      421 aagttagatg ttatgtttaa taactctttt atgaatgatg aagttcctct tgatagtgaa
      481 gaattattta aggatgatgt taataatgta tttaatcctt ttagtgaaga aatttatgag
      541 atagaggata aagaaataaa ggtcataggt gaggatgagt taaatgaata ataaatatag
      601 aagaactgtt aacagagaat ttgaaaagag tagcttttgg ccaacattta cagatttatt
      661 atctactgta ttgatggttg taattcttat cttatttagc tcagaaagta tttcaggttc
      721 tgttgaacaa gatttagcta agaatgtcaa tgcttctgtt gaagaaactt ttaaaaaaag
      781 tggaatacct gtgaaggtag ataaatctaa tgggcaagta acttttggtg aaaaaaccat
      841 gtttgatgta gatagtgatg ttttaaaacc agaggctaaa gaaatgctaa aaatgtttgt
      901 tccaaagtac atagagacta tttataaaga ttatggtgac tatatatcca aaatagttat
      961 agaaggtcat acagatgatg tgggaagtta tatatacaac ttagatttat cgcaaagaag
     1021 agcatatagc gttgctaaat ttatagtggg agatgaaata ggtgactata aatacaaaga
     1081 taaagtgact aagcatatta ttgcaatagg aaggtcaaaa gctgaactca tcaaaaatgg
     1141 tgacaatagc gtgaatagag atgcatctag aagagtagaa ctaaaatacg aaataaatat
     1201 taatcaaaat aaataattaa atttttataa aaaaaaagaa ggcagttggt gtgagcttta
     1261 agccttcttt aaggaaaaag tttatttatt tttgttgata cttaacatat tatagttttt
     1321 agaagcagtt tgcaatatat taaacgtaaa tggtcgttta aaatgcataa ctggatacta
     1381 ctgatgtaaa atatttcatt ttatataata taaaaattat acagtatcaa ttttctatat
     1441 tattgtacta taatctatta tttaaaatat tatgtaaaaa aatatcataa aaacgcatat
     1501 catgttataa ttactagagt attatgaata tggaggcgta gtttgtgata gaaataagta
     1561 taaaaaataa aaaaaattct aaaattaaaa ctttgatact tttattgata gtatctatat
     1621 caatttattt aactggttgt actacattag ataatggaaa taatcaatca aataataatg
     1681 attctttgtc tagtagtata tcaagtgata agaatgtaaa aattcatttt attgacactg
     1741 gaaatagtga tgcaatattg attcaagatg gtaaaacttt tatattgata gatgggggag
     1801 ataatgatga tgagggatta atggtagatt acctaaacaa tcaaggtgta aaagatatta
     1861 aatatcttat agctacccat tctcatgcag accatttagg tggacttgat tctgttgtca
     1921 aaaactttaa tatagaaaat gtttttgtat cgaatggttc agcagaaaca aagagttata
     1981 gggactttat aaatgcttta gcaaataagg gtttatcccc aagtgtaccg cttgaaaata
     2041 ataagttcta tttagaagat tcttattttg aagttctaaa tacaaatggg ggagatacta
     2101 ctaatgaaca atctctagtc cttgtatata ctaatgggaa tgataaagtt ttatttacag
     2161 gtgatgctga agaaggtacc gaaaaagaaa tactccctaa gcttgagaaa gtagaccttt
     2221 taaaagtagc tcatcatggt tctcgtagta gttcatctca agagttttta gataaagtaa
     2281 atcctgaata tgcggttctt ttagtaggca agggtaattc atatggtcat ccacatcagg
     2341 agacaatgaa taaattaaaa aaaatgggag taaaagtaca tagaagtgat gagtgttcag
     2401 atataatatt tgaatcaaca ggtgatggag tatttacaag ttgtaaagat ggaagttata
     2461 ataaaggcgt tagagaagat ggaaactctg gaaaatcaaa cagtaataca agtaaaaatg
     2521 attcttttaa aaataaacaa aatacatcca attcagaaga aatagtgtat tttactccaa
     2581 aaggtaagag ttatcactct acaaaaaatt gtagtgggct ttcaagaagt aaaaaaatat
     2641 tatcaggcac aattgcagaa agtaagaaaa atgacccatg tgatatatgt tatggaaaat
     2701 aacaaaaaaa caaccaattt atctataaag cttctgaact ttaaatcatt taaaaaataa
     2761 aataaatgca taaaaaaata agctataatc aatagataac acattttatc tatacgaata
     2821 gcttattttt ttaagtattt tttaatagct atttaataac tctaaataca ccagttacaa
     2881 tacctacaat ttcaacttct gagtcattga gcataattgg ttccataaaa tcattttctg
     2941 gctgaagtct tattaaattt ccttctttaa aaaacctctt aactgtagca gattcaccat
     3001 ttataagtgc aactactatc tgagaattta aggctgtatt ttttttgtct actacaacgt
     3061 aatcttcatc taaaattcct gcattaatca tactttcgcc ttttactctt aatacaaaat
     3121 tgttactgcc ctttactaaa ctggcaggga atggaatgta ttcctctatg ttttgttgag
     3181 ctaaaatggg ttctccagct gttatttgac ctactaaagg aagctctatt atttcttgat
     3241 tagctccaga aacatcattt actttactac gttctaaaac ttcaatagct cttggtttag
     3301 tagggtcctt tcttatgtat cccagttttt caagtttatt tagatgagag tgcacagttg
     3361 aagtagatct taaccctaca gcagtacata tttctcttac agcaggtgga taacctttta
     3421 atatgatttg agactttata aattccaata tcaagacttg cttttcagtt agatctaaat
     3481 acataacatc actcatttcc aaacatattt tgtttttatt tccatacact ttatattttt
     3541 aattataaca taatccattt atatctgcaa acatttgttc ctgattttta atcgtcctca
     3601 atccattcaa aattcttgac tatatcacgt tttacatttt tcttatgagc tgcataaagc
     3661 tgagtagttg tgacattatc atggtcaagt aagttttgaa catcatatat agaaaatcct
     3721 gtttggatta gagaagttgc agccgttgct cttaatttat ggggactata tccattgtct
     3781 ctagtagtat caagtggaat agatgtatat ttttttacca gtgttcttat agcctttgct
     3841 gtaattctct tattttgaag agacaaaaat aaagcatctt tttcttcatc atttaatagt
     3901 tcatctcttg ttctttcgtt ttgcaaataa tcttttatta catgttcaca agtatgattt
     3961 ataggcatta aaacttcttt cccacgtttt ctatatattt taaattcacc tcttgaaaaa
     4021 ttaaaagagg agatattgag ttctctaagc tcatttaatc taagcccgta tgtaacaaat
     4081 aatgctagta tagctttgtc acgtaattta gtttttctcc aatatacctt ttctttctct
     4141 gtaagccctt cacctgtttc tactgattca agcatcttag caacttcatc tatctcaagg
     4201 cgcttaatag catctggctg aggtttagga agttttattg gattgaatcc atcagttata
     4261 ttattatcta tctgagagtt tctgtataag aatttaaata gagtagagat ggatgatttt
     4321 tttcttgcta aagctctatt gttattttca aaaatcaatg tgtttttttc tgtatttttg
     4381 taatatctac tgcaataatc acctaagaat aaatttatat ctcttgattt tattgtatta
     4441 aaatcatctt ctgtaatatc ttttacacaa tctgcatttg ttaattcttt ggtttcaatc
     4501 aaatatgaac aaaaaaaatt aatatcttct aaataagcaa gtcgtgtaga aactgcaaca
     4561 gaacctttta aatatataaa ataatccttc ataaatacag gaagtttatt ttccaaaagt
     4621 agacattttt ctatgagttc attttctttg ataacaatat tatcaggttt atctgattta
     4681 ttatgtactt ttataatttt cttatcatta ttcaaaatta aacctcctaa aactaaaata
     4741 taaatctttt atattatttt ttgatattta taccaagtga gtataaatat ttaatttaat
     4801 cattttttac atttttaaga gattagcagt gctttagatg aaattatcac taactattcc
     4861 ctaaatccac atttaaagac tagttgaatt taagtactct tttttatttc tcaatatatt
     4921 tatagaaata ttttaaaata tattgagaaa ttttttatgc tctactaaaa tcttttttat
     4981 ataatatttt tatatgtttc taacgaaacc aaatattagt aaaatatgta tttatttaac
     5041 taaagttttt aaatgggctg actaagctta aaatatagga tattatgaga gttactattg
     5101 aaaaaataaa ccctattgcc ataaagaaac ttataaatat gttatactta actattaaac
     5161 tggatatatt caagttatca aatccaaata agtatgtaat tgaacttatt acaaaaataa
     5221 ctataactat aaagctcaga ccatttaagc tattttttaa atcagcacta ctaagtgaca
     5281 tatgtgtaga tatagaatac attaaaaaca taaatataaa atacttcaat gaatatacac
     5341 taggtgttaa caacattatt cttataaaat tggaaatatc acctaaaata atgtgtataa
     5401 acccatttat atttaaatta ttaatcatac ttacatataa ctttaaatct atattttgag
     5461 tcactttcat ataactatct ggcagtaata tcttaaaaat taaaataatc attattgttc
     5521 cacctataat aggtgcaatt cctataaaga aatttcctat actttgataa agattatctt
     5581 ttttatagct atgacttaca tatcctagta taccatcatt tttactttct attggtctga
     5641 aaaacttaac tgaatttatt ttatgcatga aaattaaaca cattatcaaa tgactcaatt
     5701 catgaacaaa cgttcctata gctccagtta caataattcc agtttttcca aaagatgaaa
     5761 atataaattt attatttaga ttttctgtaa tgctaaaaat caatccaaat acaataaata
     5821 ttcctatgaa acaaaaaata tttattacac ttatttttaa aatttcgatt atataaatca
     5881 taagttaagt cctcatgtaa aagtatttaa ctactctact tcatatccat tacagcttaa
     5941 aattttacaa gcattttcta tatctttttc ttttactaag atatagtctg tatcataagt
     6001 agaaattgca aatatgctta ttttgttgtc tgctaacaaa ctacttaact tagataaaat
     6061 tcctacaagt gaaaagtcta aaggacctag tatcttaagt attctccact ccttttctga
     6121 cttgacatca gaaggaatat tattatttaa acatacaaca cttaattcat catcagttct
     6181 agttatagag taaaacttct ctgtatctat ccatgttggt attttactgt cattatttaa
     6241 tctacatact gcatactctt ctaccaataa ttttaatttc ataatgtata tttcctccaa
     6301 tcttatttgt ttacttaaga ttatacatta aaagttacat aaaataaaac atataaagta
     6361 aaaaaggttc actatagtgt cctatttcta tagccaacct ttaaaactta attaaattct
     6421 aataaagaga tatattatct aggttcaatt ataagtttaa tggctgtttt cttatcacct
     6481 tcgatttcta tatcagtaaa tgcgggaatg caaactaaat ccattccact aggtgcaaca
     6541 aaacctcttg ctattgcaat tgattttatc gcttgattta gagctccagc tcctatagct
     6601 tgtatttctg caacgcctcg ttctcttagt actccagcca aggctccagc tacagaatta
     6661 ggattagatt ttgatgaaac ttttagtacc tccatttcaa catctccttg ttaatttgtt
     6721 aaagtatcca ttacctaaag tactaaatca taattgccat ttactaatta caatcatcat
     6781 ttaaagtata cttttataaa aatatacttc tataatcgtt ttaagaaaac ctttattttt
     6841 tttaaccatt ttattatgaa aaaactacaa atttctttat attctataag cattttccaa
     6901 tatttctaaa ttttttatat ctttgagcta taatttcctc tttatccata tctttgtaat
     6961 gatttaatct ttctaaaata taagctttta tttcttttga aacagcttct acatcttttt
     7021 gtgctcctcc aagaggttct tttataatct tatctattat ttttaaatca tataaatcat
     7081 tacttgtaag cttcataaca tcacaagctt ctttagcttt agatgaatct ttaaatagaa
     7141 tactagaaag tccttctgga gaaattacag aataaactga atgttctaac atacatacat
     7201 catttcctac tccgatacct aaagctcctc cactaccacc ttcaccaatt acaaaagtga
     7261 ttactggaac agaaagttta ctcatttcaa gtaagtttct tgcaatagct tctccttgtc
     7321 ctctttcttc tgcttctaga ccacaaaaag ctcctgatgt atcaataaac gttattatag
     7381 gtctattaaa tttttcagct tgtttcataa gtcttaatgc ttttctgtat ccttctggat
     7441 gaggcattcc aaaatttctt tttatatttt cttttgtatc tcttcctttt tggtgtccaa
     7501 ctatagtaac attaaacttt cctatctgac caattcctcc aaccatagaa gggtcatctt
     7561 taaaaagcct atctccatga agttctaaaa aattagaaca aatatgttct atgtattcca
     7621 atgtcgtagg tctctttata tctctactta atgttacctt ttcatatgct gatagatgtg
     7681 aaaaagcatc ttccttaagc ttttccaatt tctcattaag tgaatttatt ttatcactta
     7741 aatctatatt atttgcctta gaaatagtta ttaattgttt aatatcattt tctaagactt
     7801 ttattttttc actattattt tcaatcaaaa cagttcctcc tttatgccct atttcttgtg
     7861 catagcaaga atttgatata atacttcctt catttttctt ctatctacta tcatgtcaat
     7921 aaaacctttt tcaagtaaaa actcagaagt ttgaaatcct tcaggaagtt tttgatttat
     7981 tgtttgctct attactcttg gacctgcaaa acctatcaac gtatttggct cagaaattat
     8041 aatatcacca agcatagcaa aactagcagt tactcctcca gtagtagggt cagttagaac
     8101 tgatatatat ggcaataatt tttcttcaag cttagaaagt gcttgagaag tctttgccat
     8161 ctgcataaga gataccatac cttcttgcat tctagctcct cctgaagcag aacaaataat
     8221 tataggtaaa ttattttcag cagcatactc tattgaataa gttatttttt ccccaacaat
     8281 agaacccata cttcccatca taaaatcagg attcattaca caaataactg ttttaattcc
     8341 atttattctt ccataacctg tgacaacagc ttctgactct tttgtttttt ccttataaga
     8401 gtctactttt tctttgtatt taggaaaatt tagtggattt tgaaattcta catcagaatt
     8461 aaactccata aaagttcctt tatcaatcaa taaatttatt ctttttcttg ctcttaagcc
     8521 ataatgtctt gaacattttg gacatacaaa tgaattttct tctatgtcct ttctaaatac
     8581 atgactatca caacctttgc aataggtcca aaatttatca tctacactat tctttttaaa
     8641 gttgtcatct aaagaaatcg taacatactt agattctttt gatgataaaa atttttttat
     8701 cataatctat ttactcctta taatgtagca aattctttct tcataaagac atcttctata
     8761 aatttggtat gatgagtatc ttctctaaac tcctcacttg ttacaagtgc cttttgaaat
     8821 tctacatttg tattaatacc ttctacaata atttcgtcta gagctctata tattctactt
     8881 atacattctt ctctagtttc agcccaacat attaacttac ctatcataga atcatataaa
     8941 ggtggtatag tatatcctgc atatacaaaa gtatcaaatc taacaccaaa acctccaggt
     9001 aaatttaatg attctatctt acctggtgat ggagcaaaat tctttgatga atcttctgca
     9061 tttattctac attcaatagc atgacctcta aaagtaatat cttcttgttt aaaaggaatt
     9121 ttatccccat tagctataga tatttgaagt tttataaggt caagatttgt taccatctct
     9181 gtaactggat gttcaacttg tattcttgta ttcatctcta taaaataaaa gtttttatct
     9241 ttgtcaacta taaactcaat agtacctgca ccgatataac ctactccttt tactatatct
     9301 actgcaattt tatgaagttt ttgtctttct tcatctgaaa ggtatggact taaagattct
     9361 tctattactt tttgatttcg cctttgcata gaacaatctc tatcacctaa atgtattgca
     9421 tttgaatgtt tatctccaaa tacttgtact tctatatgtc taggattttc tataaacttt
     9481 tccatatata aatcactatt agaaaatgct gctagagctt ctgaacttgc catatcaaaa
     9541 tttgaaaaaa gttcttcttc ttttctaacg attctcatac cttttccacc gcctccactt
     9601 gaggctttta tcataacagg atatccaatt tctcttgcaa cttctaaagc ttcttcctta
     9661 gttttcaaaa cagattctga accaggaaca acagggatat tcaattccat catagtttct
     9721 cttgctctag atttatctcc catcaaaatc atttgttctc ttgttggacc tataaaaata
     9781 atattattat cttcacattg ctttgcaaat tcaggattct ctgataaaaa tccaaagcct
     9841 ggatgaatag catcacactt taatttaaga gcaagataga ttatattttc tatattatta
     9901 taactcttac ttatattatt tggtcctata caaatagatt catcagctat atatctatga
     9961 aaacaatctt tatctatttc agaatagata gcaacagttt ttatacctag ttctttacat
    10021 gttctgatga ttctaactgc tatatcgcct ctatttgcaa ctagtatttt ttttatcaac
    10081 ttaaatacct cctactacaa tggttttatc ttaaataaag gttgattata ttctactagt
    10141 tcttcattac taactaatac ttcaattatt tcacctttaa tttcacttgt tatctcattc
    10201 ataagcttca ttgcttctaa tatacataaa gtgtcgcctt cttcaactac atcgccaact
    10261 ttaacaaagc tatctgcatc tggacttgga gaatcataga atgttcccat caaaggagct
    10321 actactactg atagattctc attagatgtg acaggtgtat cgtttacaac tggcttttct
    10381 aaagaaagat ccactactga ttcttgttgt acacttaaaa caggtgaact tgtagattga
    10441 gcttttttag atacttctaa tcttaaatcg ctactttcaa gttttacata ttctaagtta
    10501 gttgagtcta tggcctttaa taattcctta atttcattga tgttcatttt gttaccccct
    10561 tgtattatta cctggtgcta atattatatc acaaaaaaca aatttataaa agaaaaagtg
    10621 ctgactagag aatcaacaca tcaatatatc ttttaatttt aaattaacaa ccagtaactt
    10681 atatttgttt taattttcca ttattaatat aaattataag tataaaatga ataaaattca
    10741 atattttttg caaaatacaa gagaatacaa attaatacct cgggaatttt taagacaaat
    10801 accaatatta tgcaatttag acttcgcttt ctttcaaatt agtatcattt tctttatttt
    10861 tacataggat gtactttaat ttagctatca aaacattgct atataggtta aaagttatta
    10921 gaattgcagg aattataaag taaactctag cacctataaa accaaaaact actgtaataa
    10981 gtattaatct tttatttaaa gtaaaaaaag gtatattaaa aatacttttg tcggatgttt
    11041 ctggagtata agaatatata actccaaaaa tcaaagtaag catacaaagt ggaagtagtg
    11101 tataacttga aattattccc agaaatccta tactttcaaa atatttgcta gcactatttg
    11161 tataaacaaa catgtatcca tttaaatatg cgcatataca tgatataatg ccaaaagttc
    11221 cccctaagga ttgagtgtac caattaaaaa atttagattc catatacctc acctcctaaa
    11281 actgtatata taatgatatg catttaaata gtaaaatata tctttatatg tttctgaata
    11341 aaattttgtt aatttcatta atttatgttt aagaaatttg aagtatagtg tagtatatat
    11401 taatgtagat gaagttttat agtacttatt tcatagtgct taatcaagtt atcttattat
    11461 ggattcaaaa gttgtttgta gggttttata ttttgttgag ctgaaaaatt tattataaat
    11521 gaagggatgt tttcgctttg gtagatacat tagaatttgg tcttaaaatt ttatttttta
    11581 tattatcaat aatttggatg ggtaaaataa tgattttaag aactgataag caaatagtaa
    11641 tcaatccttt gcttattggt atatctgcag tccttgtgat gttgcatacc tcacagagta
    11701 acattgaatt ttttggatta gatgtccaat atataagaat agttttgtat ataatatatt
    11761 cactgataat tttaatagga atatgggcta ctaacagaag aaatggaatt ttttagataa
    11821 tctatttcta taaaatttaa aggttgctag taacaaagca ctaatattag cgttctgtta
    11881 ctaacaacct ttattttgat tatacactta aattgaaaat agaatgattg aataagttga
    11941 cagattattt tacattgaca gtaattagaa cttcttgaga tgtatttaaa tcatttttgt
    12001 cgcttagtat aacttttacc actgcttgac ctgttttatt acctttaatt atcatatctt
    12061 cacatgaaag tacactctta tcacttacag atacaataaa atttaaatct tttggaaggt
    12121 tatcagtaac ttcccagtat ttataataac tatcaatttt cttcgtaatt atttttctca
    12181 aatcaatact ttcacctttt gctatatcaa cgttatgata tttagagtcc agtttatact
    12241 gattatcttt tgtatcaata aaatttaaat cgcaatttac atccacacca ttatgagaaa
    12301 gagaatttac tacatcgtca tcaatcaaat aattattggc aagatttatt gaatccatat
    12361 cttttagact taaagcttcc ttaggaatct cttttatatt attattccaa aaaataaaat
    12421 tgtctacatt ttcaagatat gatatacctt ttaaatttga aatgctctca ccagttgcat
    12481 aaaattctcc atctaaagcc tttatattgc ttatagtcat ctcatctgga tttatatatc
    12541 tttttacaac tgctcttaaa tttgcatcag gaaaaatatc tttaagttga ttttcgctca
    12601 aaaccttatc atttgaattt attggactta aagctgctgc agaaataata aatggtatta
    12661 aattagctaa attcatagta ccctcccaca taaatttttt attataataa tttaatttct
    12721 atgagagggt tctgtttcct tgttatatat acctactttc gtacacttta ttaatataaa
    12781 ttaaaataaa tttctactat taaacttata aacatattac tagttacgtt ttttagcttc
    12841 acatctaaat attcgcatac cttgtgacat aaatttgtct tcatactctg ttgtaacatt
    12901 attttcatac tcactatttc ctaaatcaag agaaatattc tttaatagcc aattatttgc
    12961 agcaatttca tttaaactaa actcgaataa tttttcatta tctgttttaa agtgaatttc
    13021 gccatcatct tccaaaaccc tattgtacat ttctaaaaat ccagaatgag tgagtcttct
    13081 tttactccat ctatttttag gccatgggtc acagaaattt atataaattc tcgataattc
    13141 tttagcttca aagtaatcca aaatattgct tacatctccc cataaaaata gtatattatt
    13201 caaattagaa gcatctgctt tttcaacagc ctttaaaaga acttcttcct taagttccat
    13261 ggcaatataa tttatgtcag ggttctgctt agctaaagtt gttataaact taccttttcc
    13321 agtcccaaat tcaacatgta ttggattatc atttctaaac tttaaattcc acttgccttt
    13381 taatttgtct atatcgtctc ttaaaacata ttttgtataa cttaaaagct tttcatctgc
    13441 accttttttt cgtcttcttc tcacaataat tctccttaca tataaaaaat tagtaaaata
    13501 catttttatt atacattatc tcaccaaaaa ataaaaagaa ctctcttaaa atagaaattt
    13561 atttctataa agagagttct aaacttacta aaaacttaat cttagtggca ccctgaacaa
    13621 ccagagcatc ctcctccacc ttgatctttc atattttcag gaataactct aaatccaaat
    13681 cctgtatctt ctattattat atctccatac tgactatatt catcagagct cattacaaat
    13741 tgtaattctc caacttcata agttaagtca tcttcttttt tctcatctaa agctaatcca
    13801 aaagaaggac ctccacaacc aacacctgca aagtatactc ttatattatt aggtttatct
    13861 tgattgtctt ttaagatact ttttaaagta tcaatagctg tttctggtaa agtaattttc
    13921 atcaaatcat tccctttcaa atattttatt aaaacaatat ctattatata cccatacaag
    13981 gtacataatc aattagtttt tgcatatttt actaaaactt ctacctaata ttacctaagg
    14041 ctttaaaata ttttatataa tattttatta ccttaaataa ataccctatc ataaacttag
    14101 taaacaaata aaattattat tctaaaaaat ataataattt tatttgttgt tttaatatta
    14161 taacacattt gataatgtcc aattcatata tgcaaaattt atatacttta aaatatctaa
    14221 gaaattattc aataaaaaaa tactattttt taaaaattat cattattgat aaagctctac
    14281 tatttatatt ttttagtgta ttcatgtata ataagtaaaa gcacaacggt atatactgtt
    14341 gtgctttttt gtaattaata aacaatattt tggtctataa caatgaaaaa tggctacttt
    14401 ccataattga tttcatctga cataagcaaa aagggtgtcc agctgggtca atcataactc
    14461 tccagtcatc agtaaattgc tcctctgcga ttgtagctcc acaatgaatt gcatattgaa
    14521 ctgcttcttc taaatcatta acagcgaaat ccatatgagc catttgctgt tgagattcag
    14581 gtttttctgg ttctattatg ccccaagcct ttgttttttg caatataaag aaaaaattat
    14641 atattttaat attttataat tgttgaaatt gtgtaataaa ttcaactgga tacatagtgc
    14701 gttttgaaat ttcttctaaa gctaaacctt gttttaaaag cctctttatg acgctttcca
    14761 tactttctga aatttctata atatttttat caaaatcata aaacctaaaa gttctttgac
    14821 cccatgggta ttcttttata taatgcaaaa attcaatatt tcctattcta tttatcttac
    14881 tttcccattg tttgatgtca ttaacctcaa aatacaactg aaagttattt gattgttgat
    14941 atattggtaa atcatatcca attatagctt tataattact ttgtaatcca aatccatttt
    15001 caaatgatac atgttctcct aaatctaatg tgattttttg ctccataaca tcttcataaa
    15061 acttttttga tttatttatg tctttgacaa ttagcaatac tcctccaaat ttcatcttat
    15121 cactatcctt tctttgttat aagtattata acttaaaatt ttgcaatttc actgtaaaaa
    15181 tcagacatat tagctcggta tttttgagga gttattccac agacaatttt aaaatcttta
    15241 ataaaatgtg gtatatcata gaatcctaat tcattacata tagacatcaa tgaagtttta
    15301 ttattgttta gaagttttat agatttatta atacgtacca aacgagaaaa tgacttcata
    15361 ctcaacccta ggtactgatt aaagagtctg tttaaatgcc tagaactata aaatactttt
    15421 ttagaaattt cttgtgaaga tatatttcca gagttttgaa taatcaactg aattgccaaa
    15481 ataaactcat atgagtattc aattttaata ttagaaatca ataattcttc caactttaaa
    15541 atcaatttat ctatagataa agattcatta aatatttttt taatttctaa atctaatgaa
    15601 gtattaatta tagaaaatgg aacaacttta tcaataagtt cactttgctg tatacctata
    15661 agcgggaaaa aaccagcagg ttgaaattct ataattagta taacatcaca tctattagca
    15721 atatttccta ctgtttttgg tttagtagtt ggaccaaata atagactatg taaccctgtg
    15781 gcatcataaa aaaacaccaa agttacactt ccatgaggaa taatcgtgta attatcagaa
    15841 attattgttt gatttggaaa cgatatagta aaattcgata tccaatttct taattgtata
    15901 caaggcaaga gataaacaaa attgtcttca caaactataa gtgacctatt tttatttata
    15961 aaatgaatac tttctttttt taacatatat tatatcctgt cctatcgtga atatttatta
    16021 aagtaagaag aatccatatt atctctatat atcattaact gcttttaata atagagatag
    16081 tatgaatact cattagatat ttaataaaca aataaaatta aaataatcaa taaaaaatat
    16141 agtactttta tctgttattt taatattata gcacatttat agtatttaac ttatatccac
    16201 tttacatatg tctaatttat ataattaaaa atgcttatct caaatacaat aattagtcct
    16261 tatacaatta aaccatctga aactgtaata gtacgactac tacttttggc tgcttctggt
    16321 gagtgagtta ccataattat agtttgtcca ttgtctctgt ttattttatt cagtaaatct
    16381 attatttcta tccctgtttt actatctaaa tttccagtag gctcatcagc aaatagaatc
    16441 tctggttttc caattaaagc tcgagctata gcaacacgtt gttgctgacc accagataac
    16501 tctcgtggtg tatgtttacg tctatcagtt aaaccaacta tatctaagat ttcatctaat
    16561 tgatttttat aatcttttaa atttttacca tctaataaca aaggaagcat tatattttcc
    16621 tccacattta aatttggtat taagttataa aattgaaata cgaatcctat atttctacga
    16681 cgtattatgc tcattttctc atcattaaaa tgtgatatat cagctccatt catatacact
    16741 tttccgctcg ttggagtatc taaaccacct aaaatatata aaagagtact tttgccagaa
    16801 ccagattgac ccatgataga aacaaattca cctttcatta cttgtaaaga tacctctttt
    16861 aacactcgag ttgttgtatt tccaatttta tattctttga taatattttt tgcttctaca
    16921 gctaaactat tatgtgtaat tttcatatta acctccataa ttattcaaac ttaatttctt
    16981 ctatcagttt cattttcttc ccttttataa taggcactat cgaacctatt aaagttacta
    17041 taattcccaa taacccaaca ataataaatg ttttaaaatc taaatctggt ttcattgaaa
    17101 tttttggtcc tgcaactata aagatagttt gaatctcaag tatagatatc acaataccaa
    17161 taacagctcc aagtaaacct gaagtaaacc cttcaatcaa tgtcactttt atattttgtt
    17221 tattacttag tcctatagat ttatacatag ctatagaacg tcttttttga atataattaa
    17281 tcagtagatt attaataata cctactgtag caagaagaaa aatgaaatag gtcatcttat
    17341 tcataggaga caaaaaacta cttatagtat ttaaagaatc attattaaat tcttcaactg
    17401 tacgactcca attatatgta tctccaaata aatatcttat ctgaatcata acagcatctg
    17461 gattgactgc tgtatatact aaaaaaccat aattagtttt atcaaaatca ttaactgcat
    17521 aatgtgatgg tataacagct tctacatcat ttgcgcggga tttaaaacta cctactattt
    17581 tataagaaaa atcatactta tcattagata gagttattgt atctcctata gataagccta
    17641 ctttttttag agtatcttca ttcaaaataa cagaacgttt atcattaaaa gcttctatta
    17701 cttgtttttt tatctcaaaa tttgtataat tgattccaaa catagagtta tatagtttta
    17761 tattatctgt accctctagt cttgataatg ttacaccatt accagaaatc tcattattca
    17821 taacataaag aggtaatatt tttttaattc catccatatg tctaacatct tcaataaact
    17881 cttcattcat ctttccatct gcaaaacctt gtaattctgc gtcacgaaac acatctgtta
    17941 tataagtttt gacaaagtta ccaacaacac ttattgcaat aactgcagaa atacttataa
    18001 atagtaaagt gatattctgt attatatttt tgttattttt catatttcta gcagctaatt
    18061 taccctcatt ccctaaaata tttttataaa caaactcaaa aactatagac atgatatcag
    18121 taataagagg aatcaacaca atagtagcta caattaatcc cagtaatgaa aatccaccag
    18181 ctagatacaa tgtattttca ggggatattc ttggaagtaa aatagataaa ataaacatta
    18241 tacttcctat aaaaagtata gaacgatttg aaacattctt ttcttctact gttcctagta
    18301 caatattttt tatcggcaaa tggctagctt ttttaacagg tatatatgca ctaaatgaag
    18361 aaacgattat tgctactata acagatataa tcactccaat gggtgatatt actactggaa
    18421 ttgatattcc ttgttcgaga gaatttccta acccatgaag cattaaattt aaaacaacta
    18481 caccaatagg aatagcaatt aatcctccta tacttccgta taatatactt tcaagcatca
    18541 atatacgagt tacagttttt tcattggcac caatacttct aaatgttcca ataaaaggaa
    18601 gacgttctaa tgtaataacc ttataactgc tgtatattat aaatatacta agggttaatg
    18661 caaaaaaact tattaaaaag aaaggcattg tcttttgtct agcatctgaa attatcttag
    18721 tttcatttat agtatttgat accatatatt tttcagtaga aagttctttg gataatttat
    18781 ttactagatt ttctgtaatt tcttcttctg actctataag aactcttgta tatccactgc
    18841 ctttatttat aatttttgat agagtctctt tgggtagcag tgcatttaca cctcttgtgt
    18901 tcctcaaaaa tactgtatca taagatgcaa tatcactaac ttgaaaagta taagactttc
    18961 cataaatctg caaagtaata gaatcacctt tttttatttt atattttgat gtaaagcgat
    19021 ttggaagaat aattttatca ccagaaaaat cagtaatact atcgccattt tctaatcgtg
    19081 gcttgttgat tttatttagt tgacttaagt ctgctgatat aagactaaat tcttcatagt
    19141 atcccccttt attataaata gcagagcttt ccaatacacc aacctttgat tttatagcat
    19201 ttaaatcagg tatgtcttct aaattggtta atatatctgg atttttactt tggacagata
    19261 tagtcgctgt accatacata ccttttgcca tttttctttg tgcactttca taagataatc
    19321 caattgagaa tgaaacaaaa agtaaaactg ttgataaaac tatggacaat aacataactg
    19381 ctgttctaat ttttcgttct ttaatatttg tgaaaatata ctttaatata attttcaaat
    19441 ttacaccttc tttccttatc taagatattt caatctaata tttttatact ttaatctaaa
    19501 ttaaatctct aatagactcc tccatacttt tatcattcta tttataatat ttttaatcaa
    19561 atcacccctt aaataaaaaa gattgataaa ctactatata aatataataa tctatcaacc
    19621 ttaatatatt ttttatttga ccttaattaa ccttaattaa ataggaaagg tgatataaaa
    19681 tgagctacct aatccaggta tactttcaac agatatattc cctccatgaa cttcaataat
    19741 ttgcttcgtt attgctagtc ctaaaccagt tccttctatt ttttgttttg tattgcttcc
    19801 tctataataa cgattaaaca aatttgatgc ttcttctctt gacatccctt ttccattatc
    19861 agatataatg atttcaattc tttcatttaa tgttatatgt acacaaactt tagtattttt
    19921 atctccatat gtaaaagcat tgacaataag attactaaaa gctcgtttta atagtgtaca
    19981 atcaaaatca aagttaatat tatctatatt actcttaaat tcaactatat ttgattcata
    20041 ttctggatag tttaaaatat caatggataa ttctttcaaa aatcttacta aatcataatt
    20101 atttttattt aaagggatta ttccattttt taattgatag gttaatttta aatcgtttat
    20161 aagtgtattt gtatattcta tattctttaa catgattgaa gcatatttat atactttttc
    20221 aggtgaataa ttagtactac tatctgtaag aagctctgca taccctttta ttggtgaaag
    20281 tggagttttt aaatcatgag ttatatttga aatccactct tctctcataa tatcagtttt
    20341 attttgtatc tcatcacttc tatgaatttc ttcatttaaa atatttaaac tattatatat
    20401 atcagcaaaa acacctttaa tattaactgg aagatagctt cgttttgaaa tatcgctaac
    20461 agcagatgta atatttgata tgcactttgt tacccagtaa ccataagcaa ttccagaaac
    20521 caaaattatt aaaaatataa tccctatgat tgaaaataca attgacttac cacctataaa
    20581 tttacctcca tcaaaaaaca tattcacttt agatatattt aatggaaaat atataatata
    20641 aatatagtca tttttattat ttttaattgt attaaagtat acagttccat tacttgaatt
    20701 attttggtta gctaatgcta ataattcaga attagaataa taatctttat gctcttttgg
    20761 ttctaaaaac ccataaactc tatttccact agaatctaaa atttgcaacc acaattgatt
    20821 ttctcgaagt ttttctaatc cagactgttt tacttgtggc ttattatcta taaatacgat
    20881 ttgttcatta aagttttctg taaatttttt cggccagtca ctacgaataa attccccatt
    20941 tggtttctga atagtaataa gtgataagaa aatacctatt actgtcagga ttaagcaaat
    21001 aaaaatcatg aaaaaaataa tgtatgaatg aaatactgtt ttataactag gtttatgcat
    21061 ttaatcaact cttttcttaa acttttattt tgattattgc ttatataaaa tagacaataa
    21121 ttattgatat gtaaaaattt atttaaaaat acaactatct acataaatta tatttatata
    21181 attatatgtt atcaagctat ctgttgtatt taataaatcc ttttgataac atataaaagt
    21241 aagataaatt tttccattaa ataccttata attatacaca aaatctctat atacgttaaa
    21301 cagtatagag aaaattttca tagaaccatc tttatagggg atactttata aaagaataaa
    21361 aaaattataa tatataaaaa cttcatagga gagtaacaac atcagtaaaa atatgaaaac
    21421 actatataaa aattcaaaaa tattaagaat aatgaaatac ttgaaattgc ttatatcaag
    21481 aaattttata taatataaac tggtcaaata tgttataata ttaaattgtg acaagttcat
    21541 ggaggtgttt atatgaaaaa acaaaagtcg ccaattttac ttgaaatgct tggactattt
    21601 tttggttgta tatcaatgag tattggtata aatatgtttt taaaaccaca tacaattgct
    21661 cctggaggac ttagtggtct atcattagta ctaaacaagg ttacaggact tccagtatca
    21721 gctatcatgt taattatagg tgtcccatta gtaatacttg cttttagaat tatgggtaca
    21781 aaaaattcat taaaaacttt atttggaaca gttgtatttt cagctatagt tcaattaaca
    21841 gacccattat caaaactaag atttactaat gacttattat tgtcttctat tgcaggagga
    21901 atcctagttg gtataggttt aggaataatg tttaaatcag atgcttctac tggaggaaca
    21961 gacttaattg cactcatact tagtaagaaa ttcccaggaa taaaagctac aaaattcatg
    22021 tcatgcctag atggaatggt tgttatatct tctggtatag taaatcgtag tttagaaact
    22081 gctctttact ctggtatagc actttgtgta ttaataaaaa tagcagatat gataatggaa
    22141 ggatttgacc attcaaaagc attttttatt atctctgatg agcctgaaag tttaagacaa
    22201 gctataactg aagaacttga tagaggtctt actattcttg atggtaaagg tggatacact
    22261 agagaaaata aagaagttct attagtcgta gtttctaaaa aacaagaact ttatctaaag
    22321 agattagtta aaagaactga ccctactgca tttgttattg ttacagatgt acatgaggtt
    22381 cttggagaag gatttaaaaa tttagagaac taataaaaat taatatttta agtatatata
    22441 ctattttaat taaaatacga tttattcaaa aagagtgtct cataaacttt ttagttcatg
    22501 agacactctt ttttgtataa aatcaaatgc attttcagta ttttaacaat aaaaacagga
    22561 ttatctatat tttgaggcaa ccactttatt gaaattttat ttagaaaaca atcattacta
    22621 aataaccagc atagatatta aatgattata tctattgttt tttcaattca tattgataac
    22681 aaggaacatt tttcacagta tttccagtat gaattttttt gatatacttt cctgtacatt
    22741 taaatcctaa taaatctaat gattttgtag aattttggtt ttcttcatag gttattgcaa
    22801 ttattttatt taagtttagt tctctaaatc catactgtat tactcttttt gttatctcag
    22861 tagcaaaatc atgtccccaa tagcttggat ttatacatat acctatttct gcttctaatg
    22921 ctttaggatt tatattatta aaccccatat tcccaataac tttattgtct cttttatata
    22981 ctatagcaaa gtggccaatt ttcccttttt tatatggatt tagaaaaaat gattttataa
    23041 actttcttgt atcttctaaa gatttatgct cactaaatgg taaatgtttt actactattt
    23101 tatttttata acagtcaaaa aaatcttcaa catcatctaa tgatgcaggt cttagtatac
    23161 aatttctagt ttctaaggtt ttcatttgag gatattcaga atcagacatt tctaatcccc
    23221 ctttatacat taatctaaat atactgttca tatttaaaat acgatattaa ttatataaat
    23281 gttctcaaat taaccttatt tttattttta ataaaaacta attactatat gaatctttca
    23341 aatttacgaa tttatctcta tttttatatt aaattacttg tgaaatatgt attctaaatt
    23401 atatattatt agatatcatg cttaaaaatt ctttggttgc taaggataaa gatatatctt
    23461 ttaaatggca gtaacctata tttctcttag gtattggctc ttttatatct aatttaaaca
    23521 atttctcatt ttccaaataa tctatgctaa attcttctat aacacaagac actccaagat
    23581 ttatatacgc aaattctaaa agtaattcat gagaacccaa ttctatatcc gggtttagtt
    23641 ttataccttt tgataaaaaa tattcattta cataaagtct tgaatttgct ttattttcta
    23701 gcattattaa aggcaatgtg tttaattctt ccaatgatat tttcctacct ttgtattcta
    23761 tgtaatcatt tgcacataca aatatatcat gtatttcaat acactcaaca atatttagtg
    23821 tatcatcttc tattggcatg tttataattg ctatatctat attcccatct ttgagtaaag
    23881 atataagttc tctactcgtt ctatttattg tagatacatg tatatgtgga tacttcttat
    23941 gaaaaatttc taaatatttt aacaagaaaa aacgtgcagc tgtatctcct actcctattt
    24001 tcagagaacc gtattctaat tttttaaatt tatttattct atcttctcct gatgatatta
    24061 actttaatgc agtagtgaca tgttcactta gaattttccc ctctggagtt aattttactc
    24121 ccttattgtt tctataaaat aataaagtat ctaattgttc ttctaattgc tttattgact
    24181 ggcttacagc tggctgtgac ataaacaatt ccttagcagc aagagaaaaa ctcttattat
    24241 ttacaactgc attaaaaacc ttataaagtt caagttttat attcatatat aattactcct
    24301 tatgtcaaat attagtatta tttattttac ttataattat atttgaatta taatatacat
    24361 ggtactaata tgacaatatt aattctttag gaggatttta gataatggat agattagttg
    24421 gaactgtttc aagaggggtt agagcaccta ttataagaca aggagatgac ttagttaaaa
    24481 tagttgttga ttctgtttta aatgcgtcaa aaagtgaaaa ctttgaagtt agggacaaag
    24541 atgtaattgc cgttacagaa gctgttgtag ctagagcaca gggaaattat gctcacgttg
    24601 acaatattgc aaaagatgta aaagataaat ttggagatga tactgttggg gttatattcc
    24661 caattttaag tagaaatcgt tttgctatat gtttaaaagg aattgcaaaa ggatgtagaa
    24721 aagtcgtatt aatgttaagc tacccttctg atgaagttgg aaatcactta ataagtattg
    24781 atgaacttga tgataaggga ataaatcctt ggtcagatgt tttaacagaa gaaaaataca
    24841 gagaactatt tggatataac aagcatacat ttactggtgt agattatgtt gattattata
    24901 agaatttaat caaggattgt ggtgcagagg tagaaatagt atttgcaaac aatccaaaaa
    24961 ctattcttaa ctatacaaca agtattttaa cttgtgatat acatacaaga caaagaacaa
    25021 agagaatttt aagacaaaat ggagctaaaa aagtatattc acttgatgat ataatgacag
    25081 caagtgtaga tggtagtggt tacaatgacc agtatggact tttaggttca aacaaagcta
    25141 cagaagaaac agtaaaatta ttccctataa attgtgatga agttgtaaac aaaatccaag
    25201 gtaatataaa agaaataaca gggaaagatg tagaagtaat ggtttatgga gatggagctt
    25261 ttaaagaccc tgtaggtaaa atatgggaat tagctgaccc agtagtatct cctgcttata
    25321 caaaagggct agagggaact ccaaacgaag taaaattaaa atacttagca gataatgatt
    25381 ttgctgactt atctggtgat gagttaaaag aagcaatttc aaaatacata gttgaaaaag
    25441 ataataaatc tgatgattta acaggaaaca tggtttctca aggtactact ccaagaagat
    25501 taacagacct tataggttct ttagcagatt taacatctgg aagtggagat aagggtactc
    25561 ctattattta catacaagga tatttcgata actatacaaa atagtatgtt ttaataagat
    25621 ttaatttttt tggattatat atattaacat gaaaatttat taaaacctct taatagatat
    25681 gacttttcaa gagttatatc tattaagagg tttatttaat gttcacagat aagatatatt
    25741 taaataattt aaacaagatt gtcagaaagt tatataatct taaaaattta tataactcta
    25801 attcttattt atttctgaaa taatatcact cttcaaaatt tgtcttactg gaataattac
    25861 agcaactata ctaatagtga tatttaaaat aatcatacct atgtatagag gtgtatttat
    25921 tttaagaatt ggatttatat ataaatatac acgttttacc ataaaataaa tcataaattg
    25981 tccaataaca cttccaatta ccattataat acttgcatag aatccatata aaaaaccttc
    26041 tcttatcatc ataagtaaaa acttattatc cgtaataccc atagctctta aaattccaaa
    26101 ctcatgtctt cttgaaaaaa ttaagtagct tactgtattg attatatgga acaaacttat
    26161 tgcaagaagt acaaatacaa taccatatat aaataagagt ttttgattta agtaggtatt
    26221 atttttttca atagcaatgg tataatctgt tacgatacat ctttttacat cacttacaac
    26281 actttttatg ttctcagaca attcctcact gttactatct tctgtctttt ttatacttac
    26341 tgaattataa ttttcgatat caaagttatt tttcatttgc ccattcgtca taactatatc
    26401 cataccataa tcaccaatga aatatatgtt atttgccatc acacgtttta cagtagcagc
    26461 aactacaaat tcttttgttg tataatcatt cttattttct tctttaaatt taacaatttc
    26521 atctgttggt ttcattgtct ttggcacttt aacttttatt gtatctcctg gatttatatc
    26581 aactgcatca tacatcccag ttccatccat aggtagtcta actataacct tattattttt
    26641 aaccatatca tgggtattaa tctccccatc tataatataa gaatttaatc cttctaacat
    26701 accattgtta taaccataaa tatttgtttt taaaagatag ccaccttcat tttgctttgt
    26761 acaaatacca tcaaaaaaag tctttatcct gtaatctttt tcaagaggtt taaagaaatt
    26821 tttccaaaat agttgttctt ctttaatttg catagctcca aataaatatc ttactggata
    26881 gacttttgat attccctcaa cattgtttaa tcttgaaatt ttatcttttg gtatacctac
    26941 atcaaaatct gttgtttgca tagttatttg gtagtcagaa tttaaaccat catcagcttt
    27001 cattgtaagt tcattattat ttttagtaag ctgtatagag taactagaac atagaaatat
    27061 aattccacca agtgataatg aaaacaaaat tccaataaac attccctttt tttgagtcat
    27121 gtatttatga gataatactt ttgtcatgtt agagtgtttt acactttcta atattctctt
    27181 tttcttatta gtaatcttaa agtttttcat agattctata ctagagtatt tattcaactg
    27241 atgtacaaca cgtacagcaa ttaaaattaa caacaataag ataaataaaa agcctaaata
    27301 aatagatttt tcacttataa aaaatgctcc tggaacaata tcactactca aaaatatatg
    27361 tggaaattgt tcatatattg tagacgctac tccaatacct aagaagcaac ctataggaaa
    27421 tccaacaata aaaagtaaaa ataactctaa aaatagtaga aataaaagtt gtttattatt
    27481 agcgcctaat acttctaaaa ccccatattg tgatattctc tgaagtattg aaacatggaa
    27541 aatactatat actgctgctg caccaaacac tccaacaagc aatataattg catttgtatt
    27601 tagttctaaa ttttttaaga actcaaatat attatatttt tctatatttt ttggtggttt
    27661 tactccaaat tcaactgaaa gagaccagtt tatataagtt ttttcttttg atatgttgaa
    27721 ttttttcata aatttataat tttgcttttt aatattttta ttttcatcat attttacata
    27781 aactatataa gaatcctttt ctttaggctg aaaataatcg tttacaaatc cctccagagc
    27841 agtttctggg tttgaaagac ttgataaaat accacataac ttatagattt taccatctaa
    27901 attgatttct gttccaattt ctttgtttac atttaaattg tttagagaat atgtgtcaag
    27961 tactatctct ccatctttac taggaagagt tccttttaat aattttctac ctgtcatgtc
    28021 taaatatgaa gaatcagcat ttaaaaattc tataataaaa ggttcatcta tctgattttt
    28081 aggttttgta acgccaagtc tatctacagt gtattccttt gattttttat tttctttaat
    28141 tttattaagt tgttccttat ctactttata gaaataatga taatctccac tatcttccct
    28201 tatcttttca attctacttt tgtctgcact atgaactaaa gaaccaattc ccgtcaataa
    28261 tgctactgat agtactatgc ttaaaactat agatatagat tgttttttat aatgctttat
    28321 atattgaatt gaaaatttta ctagagacat catagtaatt caccaccagt attaaccaca
    28381 actccatctt caatatggat aattgagtcg catacttgtg ctatattttc attgtgtgtt
    28441 accataagta tcgtttgatg gaattttgca ctactttctt ttaataaaca taccacttcc
    28501 attgtagttt tactatcgag atttcctgtt ggttcatctg ctaatataag cgcaggttta
    28561 tttgccaaag ctctagcaat tgctaccctc tgttgttgac caccagatag ttcgcttgga
    28621 aattttaaac gcttatccca aattcccaat gtcttcatca gcatttcaat atattcatgg
    28681 tctatatggt ttcctttatc taatgtaaca ggaagagcta tattatcata agtgtttaat
    28741 acgggcatta aactgtagtt ttgaaatata aatcctatat ttcttcttct aaacactgtc
    28801 aaatcttttt ttcctatttt agatatgttc tttcctttaa ttattacatc acctgaggtt
    28861 ggattatcta atccacctat aatatttaac aatgtgcttt ttccagaacc agaagttcca
    28921 actatagcag taaatgtatc tcgttcaatt tctatactta ctccatttaa ggcttttact
    28981 ttagtctcac cttttccata gtgttttact aaattattcg tcactaatat actcatttaa
    29041 tttctccttt caatacagat atatgttcta taaaatattg taagtgacga taattacact
    29101 catcctacaa aattagttta aactcttaca attctgtaag aagatactaa aacaacatcc
    29161 acttcctagt ttagattcta ctataatgtt tccattttct ttttctaaaa ttaatcttgt
    29221 aagatataga ccaatccctg tgccattttg gttttcaaca tttttacttc tgtaaaatct
    29281 tttaaaaata tcatttagtt ctctactatc aatacctatt ccctcatctt taatagtaat
    29341 cttcgtatat agttccattt ttattacaga aatagtaatc gtgctatctg atggtgagta
    29401 ttttattgca ttttctaaaa catttacaat tgcttctatg gtccactttt tattatgaac
    29461 taattttatg tctgaaaatg gttcgagatt tatccttata tttttagctt ctgctttatt
    29521 aaagatagta ctgatacttt gaataagagt atctttaatt agtagttctt ctacttcaaa
    29581 ttctataact ccatcctcta atttagtcat tttaaataag gattgtaaca gccagtcaat
    29641 cttaaaagtt tcatttttca tcttttgtaa aaactccttc ttctgtaatg tggaaatatt
    29701 tatattctcc agaagttcac aataaatggt tatatttgaa agtggagttt ttaattgatg
    29761 tgacatattt gatattaaac ctttaatcgc ttctttttct gactttgact gttctacctc
    29821 tatttctatc atatccttaa ttttttttac ttggtgagaa atttttgacg ctcttgtatc
    29881 ctttgtatct ggataagtaa cttctttacc ttccaatatt tgatttaaca tcaaatttaa
    29941 ttcatcatat ctttttcgat ttattttagt agatactata aatataacaa ctgtacatat
    30001 tataaaggct aatataaaca tattattcta cctcattcca taaataaccc attccataag
    30061 ctgtttttat atattttgga ttagatgggt catcctctac ttttactcta agtcttctta
    30121 tatttacaga tacaatatta tcatcaacat aattttcttc gctgtcccaa atatggtgta
    30181 aaatttgttc ctttaataat atttgacctt tattttcaat tagataactt agaagcttat
    30241 attctacaga gctaagttcc aaacattctt tatttttata tacttttagt aacttttggt
    30301 ccaattttat tccattggaa tatattactt tattattcga tttttttctt attgctactt
    30361 tgactcttgc ctttaataca gataaagaaa atggttttgt aatataatca tcaagcccta
    30421 tttctaatcc ttttacttca tcaatttctg agtctcttgc agtaagcatt ataattggta
    30481 tatctgactt ttcccttatt atttgacata catcaaatcc atctccatct ggaagattgc
    30541 agtctaagat tataaaatct atatttttac tattaaatat atttaatcct tcttgttttg
    30601 tataagcctt aaatacatta aatccatcat tctcaaatgc ataaaaaaga ccttcattta
    30661 agtttatatc atcttcaata attaataagt tcaattttac tctcctttag attttttaga
    30721 taaataatta ttttcttgca ttatcatact aaaaatattt taattttatt tatttcacta
    30781 aaaagattgt atttaaattt gttttcaaaa taaaaacatt ataatcaagc atatagttat
    30841 atatttccca atttaattac gcttaaattg aaaatataac tttattctta tataattaaa
    30901 ttatacaaca ataaagttat attttttaaa tatattttta ctagggggaa tagaattgaa
    30961 aagggttgat gagagaaata ctatgtttgc aagagcaaat tacaaaaaag atagtactgc
    31021 ttataatgac tattataaga aaaatcctga caaaaaagaa attgatgata gtataagaaa
    31081 tagaccaaat ttatgtagtg aaggaacaat gacttacaat gagttaaact ctccaatggc
    31141 aagtagtgca ttcgattttt tatctgatat caaatcttta tgcgaaggaa aagtttctga
    31201 tactaaagta gatgtagatg caaagtcaat gacaaaaaaa attaagggtc ttgcaaagca
    31261 gtatggagct tctgtagttg gtataactaa attaaaagac tatcatattt atacaaatag
    31321 gggtagacat gaagaaaatt acggtgaaga aattaatcta actcataagt atgcaattgt
    31381 atttggatgt gagatggata aagaaatgat aaatagagct ccaatgatat gtgaagttat
    31441 agaaacatca aagtgctatg tggatgcatc tatcgtcggc atgattttaa gttactatat
    31501 aagaaattta ggatatgatg ctagaaatca tatggatgct aattatttag taatgcctgt
    31561 ttttatagct cgtgatgctg gtttaggaga tataggaaga aatgctatac ttacaaataa
    31621 agattatggc tctagactta gattaggtgt tgttactaca gatattcctc ttttagaaga
    31681 tgaatatgtt gattttggac tagaagattt ttgtaaggtc tgtaaaaaat gctcttttaa
    31741 ctgcccttct cattcgcttt ctaatgatat taaaattggt gatgatggaa aatataattg
    31801 ggtaattgaa catgagacat gctatattaa atggagatat ttaggtacag attgtggtat
    31861 gtgtatatct gcttgcccat ttagccaaaa tctcgaaact ataaagaata ctacttcatt
    31921 taagggtaat aatgagctta ttcaaaaagc tttagatgag tatacttcaa aatttggtaa
    31981 aagaatattt atacctggaa atccatcttg gttgaaataa ttttatttaa taaagaatct
    32041 gtactagaat ttatcatagg acaggttctt tattaaatat ataaattttt aaatactttt
    32101 tctcgtttat aacaattcag caatgttttt agtctataat tgacattata aaatattaaa
    32161 ctaaaaggag taactgtatg gaaaaaatat tagtagtaga agatgattct atattaaata
    32221 aaactctatc atataaccta attgaagatg gatatataat tacttcaaaa tttacagcta
    32281 aatctgcact aaagtctatt tttgaatgtg aatttgattt aataattttg gatattaatt
    32341 taccagataa aagtgggttt gaattatgta atgaaataaa ggaaaattac aatataccaa
    32401 taattttttt aactgctaat gatatggaat gtgatatgat taaaggctat gaacttggag
    32461 ctttggatta tataacaaaa ccatttaata tcaatatatt taaacaaaaa attaaagctt
    32521 ttttaaatca tcttacaata aaaacaaaac aagattacta taaggatgga tatcttgaaa
    32581 ttaacttttc tgagttatct gccaatataa atggaaatca aattatattt acaccattag
    32641 aatatcgtac tttaaaactg cttactgaaa atcctaaaag tattttaaca aggaaagtac
    32701 ttttagaaaa actctgggat atagatgcta actttgtaga tgaacatact ttaacatctg
    32761 ttataagtag gattagaagc aaaattgaaa aagacaatct taagtatatc aaaacggtat
    32821 atggtatggg atatatgtgg ttaggtgaaa gaaatgaatt ttaaaaaatt ttcttttagt
    32881 tctatttatt taataattgc tgttggtata atttttacag ctattttatt tagtatctca
    32941 atttatctaa taactggtga tttaaaacta attgctctat tattaatata tacaatggta
    33001 ctttgtggat ttatagcatt aataatattt ttacttcata aaaaaatagt tatattttgt
    33061 tctaaaatat gtcacacttt agatagtatg atgaatagtg aagataatat tgaaattgaa
    33121 ttagaagaag aaactatttt atcacgtatc aatcacagat taattagaat gtatgaagtt
    33181 attcaagaaa atcgcaatag tattgctata gagaaagctg atttacaaga actagtttct
    33241 gatatatctc atcaaattaa aactcctatt gcaaatttaa aaatgattaa tactactcta
    33301 ctaaatcaaa catttaaaac agaaattcaa aaggattttt taatggatat ggaaaaccaa
    33361 ttagataaat tagatttttt aatgcaatct atggtaaaaa cctccagact agagacaggt
    33421 ataatcacac tatctaaaaa gaaaaattca atttatgaaa caattgctac agcacttagt
    33481 ggaattttgt ttgatgctga aaaaaagaat attgaagtta cagttgattg tgacccaaat
    33541 ttatatataa ttcatgacaa gaaatggact tctgaagcta tttttaatat attagataat
    33601 gctgtaaaat acacaagttc taatggtaag atacgtgtag ctacagaatg ttgggttatg
    33661 tatacaaaaa tagatattat tgataatgga aaaggaatat cagaaagtcg ccaagcagaa
    33721 atctttaaaa gattttatcg tgaagaagat gtccatgaca tagaaggtat tggaataggt
    33781 ctctatcttt caagaaaaat tatatctctt caaggtggct atattaaagt tacatcagat
    33841 attggaaaag ggtcgacttt ttctattttc ttacctaata aataaatttt taaaaatttc
    33901 atttgtaatg attctgcaac attttggttt tatactgtat ttacaagatg ttaaggaggt
    33961 attattatga gtattttaca agtaattaat ttaaagaaat attatggaca aagttcaaac
    34021 attacaaaag ctcttgatgg tgtaactcta tctattgaaa aaggcgaatt tatttctatt
    34081 gtaggtacat ctggtagtgg caaatccaca ttattaaata tgatgggagg attagataat
    34141 cctacatctg gaaaggttat tataaagggt aaggaattat ctactatgtc tgatgaacag
    34201 cttacaatct ttagacgcag aaatataggt tttatatttc aaaattataa tcttgttcct
    34261 ttacttaatg tatatgaaaa tattatctta ccaataggat tggatggaga gaccatagat
    34321 aaggatttta taaatgaaat tataaatatg ctttctcttg aagaaaaatt atatgatata
    34381 ccaagtaatc tttctggtgg tcaacagcaa cgtgttgcta tagctagagc acttgtaaca
    34441 aaaccagcta ttatactagc tgatgaacca acaggtaacc ttgatagtag aactagttca
    34501 gatgtactga gtttacttaa agtgacaagt aaaaaattca accaaacaat tgtaatgatt
    34561 acacacaata atgaaattgc acaactaact gatagaatta ttcgtattga agatggaaaa
    34621 attgttaact aggaggtgta gtatatgttt agaaataata atcgcacatt tataagaaaa
    34681 atagctttaa atgatttaaa aattaataaa cttaaaacat atctttcagg tatcattata
    34741 atgatttcta catgtttatt attaacagtg accttagttt catataatgc ctctgtagat
    34801 ttagttaatg catctccata tcatgctata tataaatctg tagatgaaaa agcaaaaaat
    34861 atactatata aaaataaaaa ctttagtggc gtaggaactt acaaattaat tggaagtaat
    34921 aaaaagacag attgtattat gtcgattgtt tatgcagatg atacagcaat taaacttatg
    34981 aattttcaac cattgaaagg caaactacct acaaataaaa atgaaattgc tatttcagaa
    35041 aaatatttac aggaatttgg tttagataaa gatattggag atagcattaa attaaattat
    35101 tatgatgata ttacgaataa agaagttcaa tgtgatttta ttattgttgg atttctagaa
    35161 aattattatc aagataatgc caagcaatac tatacagtcg tttcaaatga ttattttaag
    35221 aatatagctt ctacaccttt acaaaataaa agtaatactt ttgacgagtc aagacctgat
    35281 actgtagatg tattagttaa actatcagaa gaaaatacag agaaagattc agcttcaatt
    35341 aagacacagt taaataaaat tggtttatct ttaggtatta agaaatataa tatatactta
    35401 aatgataact atattgaatc aaatttaatt gatggtgagc agattattac agttttagta
    35461 gttggaatag ttgttctttt ttctagcgtt tttgttatat atagtatttt ttatatttca
    35521 gttgttaatt cagttcagat gtatgctaag ttgaaatcgt taggtatgac ttcttttcag
    35581 ttaaaaaaaa ttatttctct acaaggaaat attttgtcaa ttatttttat tccattaggg
    35641 gttatagctt cttgtataat tgcttacata attcaaccat tagcatggca aatgatagct
    35701 gatttattta taattttaat tttatcactg gtaatgtttt taactgttag aatttcttta
    35761 tttaaaccag ctagaattat ttctaaaata tctgctattg aagccatgca atatacagaa
    35821 actaaattta gaaaaaaagc aaaaaatttt agttatataa atataaaaaa tctagcatta
    35881 aagaatatcg agtcaaatag aaagaaaaat ttgattgcat taatatcgct aagcattagt
    35941 ggagttttat ttatttcaat cgctaatctt gctaattcaa tagatttcaa aaaacaacta
    36001 tctcaacaat ttgtctataa cgaagattat ataattagca ttaagagtga taacttatat
    36061 gagcatatta cagaaatcca acaaaataat ccactaacag attctcttaa gaatgaaatt
    36121 aaatctattc atggagtaaa aaaattaatt gaatccaaat caattaaaag taatattata
    36181 gaaccttaca tcaaagatag agacgaaaaa caatttatta ctctaattaa aggtattacg
    36241 cctgaacttt caaaatcact tgaagaatat attgtcagtg gaaaaataga ctatacacat
    36301 ttagattcag atagtttaat tataaataaa tatagaacaa aatattatgg attaaattta
    36361 aaagttggag atacagttac atttaatatc tttagtggaa atgatattat taaaaagaaa
    36421 atgaaaatta taggaatcat tgacaattcc aatacaggag gtatgttttt tgcttcagac
    36481 aaaactttag aatctctaac accatataat acaaatttag atttttctat tttaatagat
    36541 aaaaagcatt ctaaagaagt tgaagaaaag ttgttaagta taattcagaa aaattcaaat
    36601 ttaatgcttt attcatatga agatgattat agaatgatta ctagagcatt tcaatatata
    36661 attatagctt catacatttt tgttggttta atttcttgct ttggtatact aaatatgacc
    36721 aataccctaa taaacagcgt tttaattaga aaaaaagagt ttgcattact tcaagccgtt
    36781 ggaatgacaa gaaagcaact gcgaaatatg ctttatagag aaggtctaaa cataagtatc
    36841 aaagctatat gtacttcaag tacactaggt tattttggtt caaatctact ttgcactttt
    36901 ataaaagatg taattagatt agactttatt aattttaaat tttctatatt tactatttta
    36961 attttttcat tcgtattaat tggtatacaa gttttagtga ctgaattact tgtaagaaat
    37021 atagaaaaaa aatcacttac agaacgctta cgttctcagt aagaatgtat ataaaaaata
    37081 gccatttttt atacaagttt taatatgatt ttttaaaagc tatagggata gaaaattttg
    37141 actttacata attttctatc cctatacttg tttttatttt atacagatac acttacttat
    37201 atctccgagc aacatcacca gagacataaa caagcatatt ccttattttc taaatatgtc
    37261 aattgcatga cttgtaaccc ctactaaatc ttcacgttca caagtagcaa ggtgatattt
    37321 taaatataat gcaaatgcat catcatccat agagtctact gcttcacgca tatataaagc
    37381 caaaccatct gatgcgacat aatgcagtct agttacatta aatgcagaca tcaaatcatc
    37441 aatgttttct ttacgtacaa gctcaaacaa atcctttggt tcagacttag cagcaaatgt
    37501 ctgtggatca atcaaacctt tttcaatata ttcagataca ttaatatttc ctctatggaa
    37561 cccctcgtca atgagacagc catcagatat aacatatgca gcaaaaacca caccaccagg
    37621 ttttgttaca cgaattgcct catgtaaagc ttgttgttta tcttctttgt tataaagatg
    37681 atatagtggt cctaacagta acgtaatatc atatttatta tctgggaaaa cagataaatc
    37741 catagcatta ccctgagtaa tgcttatatt ttcatttgat tgagtatttt tatggaaaac
    37801 ctctatatta tgttcgacta attccactgc gtcaacatca tatccctgac gtgccagtgt
    37861 gtgagaataa cgaccagttg cagcgccaat ttcaagcaca caatcacctg attttatgta
    37921 cttatcaatg taatgcatag tagtgagaaa ttccaccatt ccatgtttta atgcaagtcg
    37981 actatcttca tcataagtat tataaaagtc aattaagtat tgttttgttt ccataatttc
    38041 acctcttcta tattagttaa taaacatcaa atagacaaat tccaatctgg tttttcttgt
    38101 cttataaaag ctgttaatat atttttcaac attttttcag cactatatct atctaatgtt
    38161 aatttttttg ttgctgttaa gacagctatg ccatgagtat aaagaaataa atctaaaaat
    38221 attacttttg cacattccaa ctctattcca atgctttccg aaaaaagtct tgcctttttt
    38281 tcattgtcaa tttctttata aaaatcattt gcctcttcca tcatcaaatc taaatcattt
    38341 ataaataaca acttaaataa atgagtttct tcttgagcaa attcaatgta tgaaagcgga
    38401 agcagtaaat aaggacttac acttttagaa ttactataat taacaacata ctgattatag
    38461 tattcatatg caaaagcaag aaattcattt tttaattcat tcatgttttc gtaacaagta
    38521 aaaattggtc gagtggaaca ctgtaattta cttgcaatac tcctcgcatt tacagcttca
    38581 aatcccactt ctcttgtaat atccaagact gtattcaaaa tcatttcttt tgttatcttt
    38641 actttaggtg gcatatatgt tcacctctcc attaaatttt tataaaacac atatgttata
    38701 taactatagt aacatatcaa gaaattatgt caagaaaaag ctttgcattt ttttgcaatt
    38761 cctaaaactt ataaataaaa catgagttgc aattaatcta ttaatagata acagcaactc
    38821 agattttcct ttaaatactc ttctttttgt ctaatatttc atatacacaa tcttctattg
    38881 aattaatatc tttttctttt ctttttttag aatcaattaa aatgaaatac agtataaaac
    38941 ctacagcaag tccccatgtt ccgcctttag cagcaattac acctcccata agtccaatca
    39001 atcccttctc aacacctgta ttacatagct ccattgatag ctttgtacat aaatatcctt
    39061 gaactaaaag tgttactgac aatgctaatg gtataagagg tgtagcaatc tgcgcaattg
    39121 gataaaaaca gataaaaatt gctgaaaccc atactaatgt acccatgcca ctaaaaacag
    39181 actgcatggc ttcctttcca accttgtacc tttgagcaac acttcctgta agtgtcgcag
    39241 ctaatggacc gcacattggt atatatggag aaaagattgc cataaaaata tttcttatcc
    39301 cacttataac attagaccta tttgaattga aatctatata ttcatctttt ctattttcac
    39361 tttcagaaag tactaagttt tcacctgtta taaaatcacc aaaggcaatt atgtatatca
    39421 taaaagccat tggtatccct tgtataaata acattacact tggaaaacct attccaaaag
    39481 gagatactgt atttatcaga tttttaaaat ctactatgta aactaaattg tcaaaactaa
    39541 atctaggaat ttctatttct ttactaaata tacctactat taaactcact aaaatagctg
    39601 atactacacc atattctcct aaatgaaata aaaatttatt cttaactttt agagtatcaa
    39661 atctttcaga aaacattaca aaacaagcaa ccaaaattcc tactgttata gatataggat
    39721 aagaatcaaa tctcccttta ggattaaact ctgatattat agtcgatata ccgacaccca
    39781 ttagtattcc acctttaata gaatttggta tcttactaac taactttcca gctacaccag
    39841 ttatacccat taaaataaat attattccta aatctatttg taaagctgtt aatgcttgta
    39901 ttctttcaat gcccatgctg aactttaaca aatatgcagt tgtaagagtt atagaagctg
    39961 taatccagcc aggtacaact gggtctccca taaaaacatg caaacagtat aatattgagt
    40021 taatgatagc catactccat gccacttcat agggtaatcc caaaatttgt gtactaaggc
    40081 caattgtgcc taaacttgtc atacttgata ttataccttg aatagcttct ggtttctcaa
    40141 atctgtaatg tataaatgga attcttatct taaacattcc aaattttata tgaggttgtt
    40201 cccttctagc gagtctttcc ataacttcac tccacctttc aataactctt ataagtttac
    40261 aactttataa ttgtttataa attatcaatg tcattaaaat tagtatataa catgcaaatt
    40321 atataaacaa taaattaaat ctataaaatt gatagatttt gtgcatatat agaaagaccg
    40381 cttcattttt agttacttaa atcacttaat attagttatt taaatcactt gataaaggtt
    40441 ttttataaaa ttcaatagtt ctattccatg attcaaactg tccttttgaa tttccttcta
    40501 cagttccacc tgaagaaaaa atccctctac tcatactcat acataaagtc tcctttagag
    40561 gcataatata tggaattggt aacggataac ccatattatt gtatgttaat aattctacgt
    40621 tatatggata attattttct tcaaagattt ctaatgcctc taaacaagct tcataactat
    40681 tccatatgtt atcttctttt ccagcaatca taagtatatc tgctttggaa ttttctattt
    40741 ttattctagc ctcttttcta ttctctgctc ttttaagact tttcttataa gtactattaa
    40801 atccaaatgg aatatctttt gatatatttt ttttctgttc ttcaaagaat atatcattgt
    40861 ctactttgat atatggaaat ggctctcctt tatatgacca tgatgaagta tcatttccac
    40921 tcatcaatcc attaagagct tggaaacaat aaatgtgagg ttgtgatact acaacctttt
    40981 taatttgttc atatcttgaa gcaagtaaaa aggccaattc tccacccttt gatgtcccat
    41041 gtacaaatat ttctttagta ctggtaattt cattttcact aatccactca aatacttttt
    41101 caaaatattc taatggaacc tcttctaatt tatctggtaa cccttctaaa gcaaagtatg
    41161 caactgttag tacattgaat cctctagatg caagtggagc tgctaaaagg tctagagcgt
    41221 ctaaatttcc atcagaacca cctagcatta aaattgtttt attattagaa ttttgtttat
    41281 aaaataattt tcctataaac tcatcagata tgtattttgt ggtaatatct tctgatttaa
    41341 atattctctt taattcaact tcttttcttt caatagaagt ttcaaatatc atattcataa
    41401 ttattggttt atcaatagat atattttctg caaaattttt accttcagtt ttagattttt
    41461 ccagcgaata aattaacccc atacaattat cagccttata agtaccttct ataggttcaa
    41521 ctaaatctaa atctacttct cctttttcat ttgaacaaaa cactccataa gatgaaaatt
    41581 cttctccctt acaccatgga aattccattt tcacacttat tttaagttta gtatttggaa
    41641 ttaagtctga aaccataatc ttaagtcttt catccacaaa tgattctaca ttgtatacat
    41701 ttactttcat aatctatttc tccttataat aattatttat gttttatata aaacagcttt
    41761 atctaataca agataaataa atttttaaat taagacacca tattgactat ttcattttat
    41821 caacatattt catctttgtc aacatattgt cttttttagt aatttaaaat tatggtctat
    41881 atgaaatcca gttgattttt ggctaattaa agataggaat gctattaggt ttagaatata
    41941 tatattcaaa ataaaaaacc actcatttaa agaatggttt ttaatataaa ctatttgtta
    42001 ttaataagga tattttttta tttaaattta tataatcgaa catctaatat ttaatgttta
    42061 ataaaattat gcatttgcaa aagtatatat ggcattaact cttgctacat ataaattctc
    42121 atcactacat ccaatatatc tagcatattt ttcaatcttt tcttttgcat tttcaacatc
    42181 attttcatcg ctctccatta actcatttat ataaatatcc attaatgacg ctttatattc
    42241 tcttatatca tagcctaaaa attcagtcaa tctctcaatt tccttactaa aatctccatc
    42301 ttcttttacc aaaaattcgt atacatcttc cctatatgga tttaaagtta ttatttgttt
    42361 tactactttg cattcgtcag ccttcccaat aaaaccatct ttataattat taaataaggc
    42421 attagatttt tttatagatt cttcatcaat ataagaatgt accgcagtta tacgattttc
    42481 tataagggca tctacaacag cataatgaat tttaaaacaa tcattgtata aataattgct
    42541 cattttcttt attgtcgatt ctatttctaa gaagctcgcg tggccatttt ttttattttt
    42601 atttggtata ataaaagttt tattcaaatt attaaaaagt ctcttaaaat ctaaatattt
    42661 ttcacaataa acacttttaa aggtatcgat atctatagtt ataattccaa aacttactat
    42721 agtctcaatt cctttcttaa aagactcttc tatatatttt tctcctaaac ttaaacctct
    42781 atcagatatt tgctttagat tttgaaaact atttaaacaa tctctttcaa agtttttaga
    42841 tatttctaaa gcatataatt taaagatttt ccttatctta ttataattat tttttgtatc
    42901 atcaaatctg ataatagctc catttacatc aaaagtaatc attgagtttt aacctcccca
    42961 ttagtttcat caataaaata aatttaatat aaactttata atcataatat taaacttatt
    43021 tatactataa ttattaattt gatgataaaa gctattttcc ttctaaataa aaaatttgtc
    43081 taaagtttct aaaaaattta gacaaatctt aggttattac tctttaaatt atttttaaat
    43141 tattccaaat acgccaaata atattggtat aaatatagct ggtaacaaat tggctacttt
    43201 tatattcgtt aatttaagta catttagacc aagtcctata attaataaac ttccagctgc
    43261 tgtcatttct gtgactacag gatcacttaa aaatccattt aaaaatgatg ctcccacaca
    43321 tataatacct tcatacaaaa atacagatat tgcagaaaac attacaccta tacctaaaga
    43381 agcagtaaat ataattgaag ctattccatc tataacagat tttacaaata aagtatcatg
    43441 acttcctgta agaccacttt ctaatgaacc aactactgcc atggctccta tacagaataa
    43501 taaactagat gatataaaac cctctgctat agaatctttt ttatttcctt tagaaaattt
    43561 actttgtaaa aaagcaccca acttatttac ccatttgtca atatctatta attctcctat
    43621 cagagcacct acagctacgg atattattgt cactaatgtg ttttttcctt ctagtgctcc
    43681 tgatatacca atgtacaata cacataaagc aattccattc attatagtat cgcttactct
    43741 ttgaggtaat cctcctttta ttataagacc tactatacat ccacctgcaa ttgctagact
    43801 atttgctatt actccaaaca ttttttctcc cctcgattag ctaattgaaa tttatcctat
    43861 tattaaaacc taaacatcta tactttgtat tggatatttt aaatattcca aaaattcttc
    43921 aaaacctttt ctagatatat ttacagtttt agtatttatg ttaggatgaa aatttaagta
    43981 atcttcttta attacatctt tatctatgta aagctcaact tttctttctg tatcatttat
    44041 taatgaaaaa ggatttacac ttccaggaag aagtttaagt acattgtata gtctttcagg
    44101 tgaagcaaac gataatctag aacttcctat cttatcttta agtgagttta aatcaacttg
    44161 tttttctcct ttaactacaa taagataata cttatttcct ttggcatttc ttaaaaataa
    44221 atttttacat tgacacccct ttgttattcc atctaaaatg actaattgct ctgctgtata
    44281 tacagcttca tgctctacta catcatattc aacatttaat ttatccaaaa tatcatatat
    44341 tttagtttca ttcatgctag attcattttc atcttgttct tttttattat ttaaatcact
    44401 catacttttc tccttaaaca cttcatcata atatcattgt gaggtattat tctactatag
    44461 ctattgctct tactggagct ccatcagcat cattatactt aaatggtgct gctataaata
    44521 gaaatttttc tggaacattt tctaaatttg taagattttc tatgattatt tttccttttt
    44581 caaataaaat atgatgcact tcaaatactg atgtgtcata tctatccact gatagcatat
    44641 ctattcctat gccttttata ttagtattag ctatatagtt tgcagcttct tttgttaatg
    44701 taggataacc tacatagtac tgctttttat cccaaaattt tgaccaacct gatttaaata
    44761 ttataaaatc actatttttt atttcatctt catatttttt tagatattct aattctatat
    44821 tctcatttcc cttttcaagt tccaatacat aagcttttcc aacaaaattt tctatatcca
    44881 acttatctag ggtctcacct ttagtataca tatgtcttgg tgaatccata tgagttccat
    44941 tgtgagaaaa tacactaatt aatgtttctt gataaccatt ttcttcaata atagctactt
    45001 tcttgatatc tggtctatta ggctctgcat atacaggcat gtcattatgt gtcacatgag
    45061 ttaaatcaaa aaccttcatc tttatatacc ccctatgttt ttattttcta ttatatacct
    45121 aaattcattt tatttctatc agattttatt ccattatata ccatactact atatattttt
    45181 tataaacctc aagggattta ccgaaaaatc ttggaaagaa ttatcagtaa atataacatc
    45241 ttcacccaaa aaacgtttat accttccttc ttctttcttt aaagtaattc tctgtttttg
    45301 tgaatgatta ttaaaaacca ttatcttaag aggaggtttt tttctattag tctgcactct
    45361 ttttaacatg tattttatgt gcatatcagc ttcaggaaat gaatatccac aaaatattaa
    45421 aaggtcagta tctcttaaag ttttttctgt ttcattccaa acattactta aaaatatgtt
    45481 tgacatattc ttaaaatatg ttggtggcac tataataggt tctgttaact caccacactc
    45541 taaacatttt gtctctgaac tattttcaat aagcttcatg acaccacctt catgtggtgt
    45601 aagagttaca ctattacaaa tggggcaata aagccaattc aatgacccat gtatcttata
    45661 taatttgatt aatggttctt ttggttttct ccaatttaac tcctctttaa aatttgtaaa
    45721 ctccacacca taatcaagca taattggcaa atcattctta tctcttaatc cagtaactgt
    45781 attgtctata tgtatatcat aatttgcact aataaaagta gtatcaagaa gcaaatcatt
    45841 ttccaaaaga ttttcaacta aaagtttatg atatttatta tctgttctag gtgtattatg
    45901 aattgcttca gccattagca gtattaaata ttgtcttaaa aaacgtatac tatcacttct
    45961 gttatttaga ttttctagtc caaaatttct aaatgcttct tttctttgtt ctgctaagtc
    46021 taaaagacct aaaacttctt caaaggtagg aaaatttgca ttatctatat tatcttttac
    46081 tatatcaata ttgaacatct gtttaaagaa aatatacaat tctctattca ttttggtatt
    46141 ataatttgtg ggatttagtt ttttaaaata ttcgctaaaa agttcatttt gaataggtag
    46201 attctctgct gctgaagctc ctgctcctaa aaatattgct attttcatat agttcctcct
    46261 aatataaata ttactcctat ttttatatcc attaaatatc catatcattt attttatgat
    46321 acaacaataa agctgtcttt tactagaaaa aatcctatta caagacagcc ttatattata
    46381 ttaaatcttt aataattcgt aaatagaaag agcatatatt tgagtagctt ttataatatc
    46441 ctctactatt aagtattcat tagcttggtg ttctgtttct ggttttcctg gaaaaatagc
    46501 tccaaatgca acacaattat ctaaagctct tgcgtatgtt gctcctccag atgaaagtgg
    46561 tgttccatca agaccagttt cttcttcata tacttttcta agtgtcttaa caagaagagt
    46621 atcttctgga acatagattg aatccaagaa atcatattct tcataattta aattgtattt
    46681 atctgtcatt ttctttaact cttttacaaa atcatccttt ttgtatgtta ctggaatcct
    46741 tacatctatt cctgcaaatt ctttttcgtt atcaatagtt actctaccta tatttactgt
    46801 tagtttacct gatacatcat ccttgcaatt aggaattata ttgtttccat tagcatcttc
    46861 accaataact tctgctaaaa acttaattat attagaatct atacctatat tattaagagc
    46921 tatacaaagt ctagccactg catttatacc agtatcactt gctgctgaat ggacactttt
    46981 tccaattata cagattttat taccttcaac agtatactca aaatttaatt tatcaagttc
    47041 tttttttaat ttatcagagt attttccaat atagattgct ttacctggaa ctgcatttaa
    47101 agcctttcca actgacaact ctatatcact tttgctatca caagtcaaat gaacttgtaa
    47161 aagacctttc tctgcatttg ttattgggaa tctagaatct ggagtaaatc catagtttgg
    47221 tatttcttca ttattttctt tatatttatt tatacatctc caaagatttt cttcatcagc
    47281 cccaaaaatg aatcttatcc tcttattaaa gtctacattt aaatccataa gagctttcac
    47341 tgcataaatt gctgatattg taggtccttt atcatcttgt gttcctcttc catacaattt
    47401 accatcttct aaaacagctt caaatggagg gtaattccag ctttctaaat caccttctgg
    47461 aaccacatca acgtgaccaa gtatacctat cattttttca ccttgtccta tttctgcata
    47521 tccataatat ccatctttgt atactgtctt aaatcctaaa gatttacata agtctaatat
    47581 acctcttaaa gctttatcta cattttcacc aaatgggcaa ttttcagttg cttcagatat
    47641 aacactaggt atttttacac tttcttgtat tgaagaaatc atttcatctt gtagagaatt
    47701 tactttttct ttaatttgct ctttcatatt atcacccttc aattttcatc ataatatact
    47761 aataaatatt ttgacctttt aaaaaaaaaa tatgcttatt ttttcagttt ttttataaat
    47821 tcaatcgctt ttaaagtccc catttttgaa tggtcaaatg taagtccacc ttgaaaataa
    47881 acattataag gaggtcttat tggagcatct gcacttaatt ctatagaaga accttgtata
    47941 aatgctcctg ctgccattat gacttcactt tcgtatccag gcatgtccca aggaacaggt
    48001 tttacataag aatcgactgg tgcagcttct tgtatacctt cacaaaaact tattacttca
    48061 tcagcattat taagtctaat acattgaata atatcacttc ttaagtcatc atattttggt
    48121 aatacatcat atcctaattt ttcaaaagct cttgagcaaa agatagctcc cattacagcc
    48181 tgagatacta tataaggcgc caagaaaaaa ccctgaagta catttctagt tgttccaaaa
    48241 gtaagaccac attcttttcc tattccagga gaagtcattc tataagatat aagctcaatc
    48301 aaatcttttc taccagctat atatccacct gtcaatgcaa gcccaccacc aggatttttt
    48361 attaaagagc cagccataac atctgctcca acatcagtag gctctttggt atctaaaaac
    48421 tcaccataac aattatcaac cattactata gcttctggtt taacagactt tattacttct
    48481 atagcttctt ttatatcact aattgaaagt gattttctcc aagaatatcc ttttgacctt
    48541 tgtatcataa cgagtttagt tctatcattt attttgtttt taattccttc taaatctaag
    48601 tttccatcct ctaaaaaatc tacatcatca tatgtaacac catactcttt caatgaacct
    48661 ttttcttctc ttatgcctat aactccctct aaagtatcat atggtctacc agtaacagat
    48721 aaaatttcat ctcctggtct aactatacct tgtatacata aagtaagtgc atgtgtacca
    48781 tttacaatta ttggtcttac aagagcatct tctgtattaa atactttaga ataaatttcc
    48841 tctatttttt cacgaccaat atcattatat ccatatcctg tagtccagtt aaagtgcata
    48901 tcacttagtt tagattcttg catagctttt aaaactttat attgattata ttctcttatt
    48961 tcttttattt cttcaaactt atcttttatt tcttccatta tttcttgcga tagtttaaaa
    49021 gtatcatcat ctattccata gtagtctttt aataattctt ttgtctcatt aagcatttta
    49081 tcacctgtct ctttattatt ttatttaaac atgtaaagga gactatttta ctaaaacaaa
    49141 taaattatag tttataagtt agtataagtc tcctctcaat catcttaaat taaattaatt
    49201 atctatctgt tgttattatt attgttgttt tggttttgat ttgttagatt aatatacttt
    49261 ccaggttgta tagttgatac agcatgttta taaatcatgt tttgttgtct attatcccct
    49321 tctattaata ttatataact atcaaacccc tttacaagcc ctttaacttg cactccatta
    49381 actaaatata tagtaacagg tatcctttct ttccttgcat tatttaaaaa caaatcttgt
    49441 aaatttaaaa ctgtattttt cattagattt gtaccctccc aagattaaat tgaacttcta
    49501 aaatattcct accttatatt ctatataagt tatgacaaat tttcaatatt aagttgtata
    49561 cttaaaaatt tatatattat tttatagaat ctttaatata taagattatt tcatttttta
    49621 attcgtctat attttcatat tggtctaaat caaaccattt tgctgtttta tatcttttaa
    49681 accatgttat ctgacgtttt gcataccttc tagaatctct tttaattatt tcaatagctt
    49741 cttcgtatgt atattctcca tccagatact ttaatatctc tttataacct ataccttgca
    49801 ttgatatcat atctttttta aatcccatac ttaaaagttt ttttgcctct tcaaccaatc
    49861 catttttaat cataatatca actctcatat ttattctttg atacaaatgt tctctatctc
    49921 tatttagaac tattattatt ggttgatatt cttcattaaa ttttaaatca cttgaaaaat
    49981 cattcatttt cttaccactt agacaaactt caagagctct tatgaccctt ttagtattgt
    50041 ttttatggat tctattagca gattcttcat caagttcttt taacttatta tgcatgtaat
    50101 ctattccctt ttcagcaagc tgtttttgaa gttcttctct taattcatta ttggcatcag
    50161 attgtgcaaa atccatatta tatattaaag agtttaaata aagtcctgtg cctccagtta
    50221 ctaaaacaca tttttccttt tcatttattt catgtatata tttttttgct ctttgttgaa
    50281 actctgaaac tgaaaatgga tagtcaggct taacttcatc tataaggtaa tgcttcactc
    50341 cttgcatctc ttcctctgta acttttgcac ttccaatatc catatattca tatatttgca
    50401 tagaatcagc tgaaattatc tctgcattca tatcttttgc taattttatt gacaaatctg
    50461 tttttccaac agcagttgga cctgtaagta ttataagtgg tatttttttc ataacattcc
    50521 tttccatata ttttaaatat ccaaatattt tacataattc ttttaaacat tttttctatt
    50581 tctgtcttag atatttcgac cattataggt cttccatgag gacatgtaaa tggattctca
    50641 cacttttcta gctgttccaa taaacttttt atttcaatat cgtatatttt atcatttgct
    50701 tttatagcag acctacatgc catagatgca aatctctctc cttttaaatc ataattactt
    50761 gtaatttctt ctatattatc aattatttga agtataaatt tctcagtttc aggtactcca
    50821 aatatagtag gaacacatct taccattata tgattattgc caaaaatttc tagctcaaaa
    50881 ccaaatttca taaataactc caagttattt tcaatttgaa gcatatctat atttgatact
    50941 tcaataacca ctgggtctaa aagtatttgc atatttatat cttgtctata gaacttctcc
    51001 atatatcttt catatagtat tctttcatgt gcagcatgtt ggtccaacaa atacatagaa
    51061 tcgtctttgc tcaaaattat ataagtatta aatacaactc caattacaaa atatccgtat
    51121 aaagaaaact tgcgttttga actacacaag tattcttctt cactgtcctt aatactatct
    51181 cctaagtaat aatttccttc atttttaatt ccatcaactt gaaactcttc ttgtatatta
    51241 tcatttgcac tatcttcact tagataatta atgtttttta catcatcttc tacacttgca
    51301 tttaggactt cacttactga ttgaaattca tttattggtt tttcacttga taaagtaaca
    51361 acttcaatga cttcatcctt acctttagta atattactat ttttaggagt agattctaat
    51421 aaatcattat ttcttaattt ataatctgta cttttttctc tactgttaat agcgattcta
    51481 ggttgtgttt ttttatcact ataagtagca tattttccaa taagatttga gtgtattaat
    51541 ttaaccttta aaaaatctct aagttctata tacacttctt gttctttttc aaatttaatt
    51601 tcaagtttat tggggtgtat atttacatct atacatgatg ggtctacttc tatatttaag
    51661 aagcacactg catgtttacc tattggaatt atagacttat aactttctgt tattgcatct
    51721 atgattattt tactttttac aaatctttta tttatataga tatgttgtaa gtttttattt
    51781 gaacggtata tattgttatt acctatatat ccattcattt taaagtgatt gcacttaaac
    51841 tctacatcta ttatattttc cgttatttct tttccatata tacttctaat agtgtttaca
    51901 agttttccat cccctggagt atttagcatc tgtttattgt tatttgtata tttaaattga
    51961 atgtttggat tacctattgc aagtttattt atcaaatcac ttatgtttat agtttctgca
    52021 tgagtagatt ttaaaaattt ctgtcttgct ggtgtattaa agaaaatatc ttttataatg
    52081 atggtagttc cattagtaga acctattggt tctttcgata ttatttttcc accttcaaca
    52141 tatattttag ttcctattat ttcatcttta gttttagtcg tcatttctaa ttttgataca
    52201 gctgaaatag atgccaatgc ttctcctcta aaaccaagag agtataaatc atacaaatca
    52261 tcaatttttt taattttact agtagcatgt ctcaaaaatg atttttcaac ttcacttgaa
    52321 ggtattccta ttccattatc tgtaatctta attagacttt ttcctccatc aattatatct
    52381 atggaaattt tatttgcacc tgcatcaatg gagttttcaa taagttcttt tactacagaa
    52441 gaaggtcttt ctacaacttc acctgctgct atcttattta tagtcaaatc atctaggatg
    52501 ttaattatat ttttcatttt tacacctcta agattttatt tcttttgctt ttctttgaag
    52561 attataaaga gagtttatag catctaatgg agtcatattt aaaatatcca gatttaaaat
    52621 ttcttctgat agtatatctc tatttacact atcaaaagag atttgagtta aggctacttc
    52681 ttttacagaa tcttcttgat taattttctc tttatcatca ttttgcttca ttaaagcaac
    52741 ttcatcattt aatgctttaa atttagaatt taatttatca taatcctttt ttatatgttt
    52801 gtagtctttt actataagtt catgttctat ttttagagat tcatatttat tcttaaaatt
    52861 actttgattt accttaacta attcttcgtc caaattacta ttaattatat tattgttttc
    52921 tttatctcca tttattgcaa cactgttgta aacatgattt ttttccaagt ctttaagtat
    52981 atattttgct ctttctatga cttcgtctgg taatttagct aatttagcaa catatattcc
    53041 ataactcttg tctgctccct gaggaattat ttttcttaaa aatattattc cttccccatc
    53101 ttctttgact gctattgaat aatttttaac ctctttaaac tcttcttcta aatcagtaag
    53161 ttcatgataa tgtgttgcaa ataatgtctt acatctaata tttttttgaa tatattccac
    53221 tattgaccat gctaaactta taccatcata ggtactagtt ccacgaccta tttcatctaa
    53281 tataactaaa cttctctctg ttgcattttt taatataagg gatacttcgt tcatctctac
    53341 cataaaagta gattgacctt gagataaatc gtcactagct ccaactcttg taaatattct
    53401 atctaatatt ggaatatcag cagactctgc tggtacaaat gagcctatat gtgccataag
    53461 agctattata gcagtttgcc tcatatatgt tgatttacct gacatattag gaccagttat
    53521 tatgttaata atgttttctc cacgatttaa ataagtatca tttggaacga aattttcctc
    53581 tcctactata ttttcgacaa caggatgtct accatttctt atatcaagtt tattattttc
    53641 atttattgct ggttttacgt agttatttat atgtgcaact gttgcaaggg acacaaaaac
    53701 atctatatta gctatagtct tagccacttt ttgtattcta tctatgtttt tatatattgt
    53761 atctcttatc tctacaaata tctcgtattc taaagattta atcttttcct ctgcatgtag
    53821 tatcttttct tctatttcct ttaattctgg agttatatat ctttctgcat tactaagtgt
    53881 ttgctttctt atatatgtct catctagctt tgcctgttta aagttggctt ttgttatttc
    53941 tatataatac ccaaaaactt tattaaatcc tatttttaat gatttaactc ctgttttttc
    54001 tctttccctg ttttctattt cctttacaag aaaggctcca ttcttagaaa tctctcttag
    54061 ttccttaagt tcatcactaa aatctgattt aattatgttt ccatctttta tggttatcgt
    54121 aggttcttct agaatagctt catctattaa attgtatata tcatctaatt tatccatttc
    54181 tgaaacatac tcttttagga tttttgcatt tgataaattt atagtatctt ttaaattagg
    54241 taacttttct atcgaatttt ttaagtgaat taactctttt ggtgttactc tctcaaatgc
    54301 tatctttcca catattcttt ctatatcgta tatattttta agtatatcat ttaggtcttc
    54361 tcttaatata aagtcatctt ttatttcttc tattacatct aatctatttt caattttaga
    54421 tttatttatc aaaggttctt ctacatattt tcttaaaagt ctacctccca ttgctgtaga
    54481 agttttgtca agtacatgta ataatgaacc ttttttctta ttccctctta tagtttgagt
    54541 aagttctaaa ttagttctag taaacatatc tagaaccata tattctgatg aattgtatat
    54601 atttatatta ttaatgttag atgttatttg tttttgagta ttgtatatat aattcagaag
    54661 aattgataag cttgacttta ttagaccttt atcatcaaac tttagttttt gtagataaac
    54721 atctggaaaa tattctttta atatatttat atccaaatag ttatcactaa aactttcatt
    54781 tatgtatata ttacttacag tagctatatc tctaagcttt tctataaagt ctaaatcatt
    54841 tataattatt tcagttggat ggatttttgc aatttcttca attaccttat cttcatttaa
    54901 acatgttgca ttagtttctc ctgtacttat atcaacataa gttagaccta tattagtacc
    54961 atccttatac aaagataata aataattatt ctttttattt tcaagtaaat ttccatctaa
    55021 aactgtacca ggagtgatga cccttataac ctctcttcta acaattcctt ttgctgtaga
    55081 tgggtcttcc atttgttcac ctattgctac tttatatcca ttttcaacta attttgatat
    55141 atatgaattg gctgagtgga aaggaacacc acacatagga gcacgttctt ctaaaccaca
    55201 agcttttcct gtcaatgcta tttcaagagc ttttgaagct actaatgcat cttcaaaaaa
    55261 catttcataa aaatctccaa gtctaaaaaa cagtatacag tctttatatc tattttttac
    55321 ttcaagatac tgtttcatca taggagttaa tttattcata tctatttgca ttatcaaacc
    55381 tccttctttt ctaattaaat attatatcat agtagatgat tattattaac acaatatata
    55441 aaattttgac atataactaa aaacaatcca aaatgtatac tcacattttg gattgctaag
    55501 tttaatgctt attaaataaa aatatttttt tttacaataa agatattatt tcttttttaa
    55561 gtttaatgat attttcaagg ttatcttcat ttaactttct actatctata acaaattctt
    55621 tctttactat tgatggtttt tttgaaataa cataaattct gtttgatagc attatagctt
    55681 cgtcaatatc atgagttata agaagtattg ttgaatttac ttttttctta acatctaaaa
    55741 gccatttttg catggatgtt ttagttaatg aatcaagtgc cccaaaaggc tcatctaaaa
    55801 gcattatgtc attagaattt ataaaagttc tcaagaagtt agctctctgt ctcattcctc
    55861 cagaaagttc tgaaggatat ttatcttcat atccgcttaa tccaaacacc tcaaaataag
    55921 gttttaccat tgacctagct ttactctttt tttctttttt taaaattagt ggtagtgaca
    55981 cattatctat tatagtttta tatggcaaga gtaaatcttt ttgatacata taactatact
    56041 taccatttat attcactttg ccactatcat aatctgtaag tttagttata atattaaaaa
    56101 tagtactttt tccacatcca cttggcccta atatagaaac aaactcacct tcataaacat
    56161 caatacttat atcttttaaa acttcaatat ctttataagt ttttgataca ttttctatag
    56221 atacttttac ttttttattg tggtaaaaat tcatttgtgt aagcatcact tgccttcata
    56281 tccttatcta ttaatttata ttcttttaag aatgatgtat agttgttcca tacactatct
    56341 ttcatttctc cccatcgtgg tgcatcatct ttgtacttgc ttgctaaata ttcttgactc
    56401 tttaaagcta gtttttcatc tacttcaggt gcatgtttta ctaaaatttt tgctgattct
    56461 tctggatttt ttattgcata ttcataacct tttgttgtag cttttaagaa ttttttagca
    56521 agctctggat tatttttaag cacagtttca ttagaaatta taagtggtgt ataataatcc
    56581 aatctctcat ctaaatcttt tactggtata aagtttaagt catatccaat taaatcagct
    56641 ttaactgcat cccaaccttc aaatatccat gcaaaatcta cagttttcat agctgcaaag
    56701 aaatcatctt gaccagtatt aactatcttt aacttattaa aatcagctcc atttttcttc
    56761 ataactgctt taaaaacagc ttcttctgat ggagagcccc aaccaccata agtttttcct
    56821 tcaaaatctt tagctgttgt tatattcttt tcttttggtg atgcaaaccc agaagtatta
    56881 tgttgtataa cagttgctac agcttttatt ggaagtggat cttcactagt ctttgcataa
    56941 gtaacttgtt cttgatagct tataccaaag tcagcttttc ctgttgctac taaagtttct
    57001 gctccacttt caggtggttg tactatttca acatccaaac cttcttcttt atagtaaccc
    57061 ttatcaagtg ctacaaataa tccagtatga tttgtatttg gtgtccaatc aagcaccata
    57121 gttacttttt tagaagaagt atctttatca ttgtttttgt ctttattgtt atttgaagaa
    57181 catccagtta ttgttgccaa tgtaaaaaca cttactaaac ctaatattcc taacttttta
    57241 aaattcataa ttgcctccct caaatacctt taatctatta atctatgtct tataacaact
    57301 ttttttacag cctgtacaat tcctacaaac attaaactaa atataactac taatatagta
    57361 gatgcaaata ctttatcaag tgcatatgca ctttttgacc taagcatata aacaccaagt
    57421 cctttcgttc cacctagcca ttctgcaaca gttgctgcca ttacagcata cgttgcagat
    57481 attttaagtc cagaaaaaaa tttatccatt gccataggaa atttaaggtg aatgaatgta
    57541 ttaactttat ttgagtccat agtcttaaat aaatttaaat aatctttatc aatattctca
    57601 atgccatcta caaaacttat taatatagga aaaaaacaag taagcattac catcaatact
    57661 tttggcattg ttccaaatcc aaaccatatc ataaagagtg gtgctataat tattgtaggt
    57721 atcatctgtg taaccaacat aataggataa agacattttt ttattattga tacaaaatcc
    57781 atcaatattc caattaccaa tgatattata attgcgacta taaaaccaag tattgcttct
    57841 cctatagtaa ccacagcatg tatggataaa ttttgataat ctttaaaaaa cacattaatt
    57901 atatctactg gtgtgggtag tatatactga ggaacttcta aaactcctac catagattgc
    57961 caaagaataa gtataaacaa aaatgttgct attggatata tactatcttt gactttatct
    58021 atgatttcta agtttttcat ctatagtcag acctccagct ttttcatcta ctctagctac
    58081 tgttatgact ctttcacatc caagattaaa agggatttta tgtacctttt ttaataattc
    58141 aaaaacttca tcaaaatcac cttcaacagt agtgctcatt gctcctattt cacatttaag
    58201 accacttttt tcaatttcag caatacaagc atctactact ttatacatct cttcttcacc
    58261 tttgtaaggt cttagtggca ttactgctat gtctgcgatt accatttaaa tcactccttt
    58321 aaaaataatt aatacctact aggtatattt tgttttttat taaaaaattt tattactaaa
    58381 aagatattat atttaaataa aagaaaagtc ttatccaaaa taggataaga cttattttta
    58441 tcttaactgg tctccctaca ctggcattat ccaaacaggt tcaaagggtc gagataaaat
    58501 ctcctctcag cacattagct ccccgaaata tattatatct tttctacttg attatactac
    58561 acttatcata ttttaacaaa ttttttattt atattagata ttttatccgt tcaaaaatat
    58621 ctaatataaa ttgtacatta ttacaccaaa taaattatct taaaatggta atttatcaac
    58681 atcttccaaa actagattaa ctgaattttc tagtttttat tttgctattt caagcatatt
    58741 tggatgtata tcaattccat acaaatattg tgctaaattt ctgttttcac tcatctaatt
    58801 tgcaatcgtt acaaattaca gattagaaat agcttttaga ctctacttat ctttatctac
    58861 aaaaaatcct tcaataaatt cattaataat attcagtaat ctaaaaataa acctctatct
    58921 agatttttaa gatacaagcc ttttaggaag tatcttttgt gataatataa aaattactca
    58981 tcattatcat caaaatcctc agcaaccaac attttagata agaatcaaac tctataatat
    59041 aattatttta tccaatttat ttttgagaaa taaaatattt ttttaatttt taaatttttt
    59101 aatatgcacc ttgaaaaaag aaacgttttc ctatattatg gtaatagtag aataaaacta
    59161 aataggcaaa actagagaaa tttagtgacg caaagctata gggactaaga cttatgaaat
    59221 gagttatgtc agccagttgc caaagagata ttttcttttt gtttttatga atgtttttta
    59281 gggggatata tgatatatgt ttatggataa aatggataga tgtacacata tactaactgc
    59341 atatatatgc agttcacgcg attactgcaa ttttatagat acacaattaa atgattttat
    59401 actagaatat ggagagaatg tggtagaatc ttgtttgcat caagtgatgg tattggtaag
    59461 cagatataat taaagaaatt ttattttcta gaaaaccctt tttagtttta tctacgtttt
    59521 ataattcatt aaagaactaa ttaaaataag cttcattata tatttttcat aaagtaaaca
    59581 gttgagttta tctcatatac tgtttacccc aattacataa ttctaataat atagattcta
    59641 atgatttacc acgtttagta gacaaatatt caacttttgg aggaatagtc ggataagaaa
    59701 tcctcttaat aagtccatct ctttcaagat actttaattc ttgtgacagt atcttatgac
    59761 ttatatgaac aacttctttt tttaattgac tgtaacgtat tggctcttgt tttaaaatat
    59821 gccataaaat aattgccctc catttacttc ctatcacagt catggtaaaa ccaattgaac
    59881 aattaaaatc tttttgtctt tcttcaatat ttggaaattc ttcaaaatta ttatctatat
    59941 ccatctcaat cctctctttc aaaatagtaa gtatctaact aaaaagtgca ttcttgttta
    60001 gcgtactaat tcgtaatata atcttgattg tagtatagag ccttacataa tactactttt
    60061 ttagatgtat atgtttaaac tttaatatag acatatgtta ttttattaat tttatttaaa
    60121 cagataataa taaataataa tttatctcaa gttttctatg tagataaact aatctaatgt
    60181 ttagaaagga ttatataata tgaataaaaa atttcgtctt tatcaagttg actcattaca
    60241 aaagaaaaat ttacaggtaa tccagctggt gtaattacaa atgctgatgg cttatctgaa
    60301 tcacaaatgc aaaaaatagc aagagaatta aataattcag aaactgcttt tattttcaat
    60361 aacttggcta aaaatcatca agaaaattat gatgtacata tcagattttt tacactaact
    60421 aatgaggttc ctatatgtgg tcatgctact attgctgccc attatgttag agcagtagaa
    60481 aaccaattca ataacaaaac agtatttcaa aaaactagtg ctggaatatt accagttgat
    60541 attataaaaa aagataatga ttatgaaata attatgacac aaggaaaaat tgaagtatct
    60601 ccaccgttac aacaaaccta tcaaaaaaga ttacttaatg catttggtat tttaaaggaa
    60661 gatattcgta cagattgtcc tattgccata tcatctacag gacattcaaa agttatgatt
    60721 ggaataaagg aattatcaac attaaatagt ttatctccaa atttatatga attatcgaaa
    60781 ataagtcaag aaataaaatg taatggatat tatattttta cattacataa taaagaaact
    60841 ctacaagttc atggaagaat gtttgctcct gcaattggta tttcagaaga ccctgttaca
    60901 ggaaatgcta atggaccctt aggtgcgtac cttgtacatt ataaagtaat acctacaccc
    60961 aacacagagt ttatatttga agcagttcaa ggagaaacaa taaaacgcaa aggcaagatg
    61021 ttagtaaaag taattatttt agataataaa ccagttgaag taaaaataat tggaaaagct
    61081 gtaattgcat tctcaacaaa catagaaatc taattataga ttccttctaa gtaaattttt
    61141 gaacttttta atactaattt aataacaaac taatttatat acaatcaaat taattttttt
    61201 attatttgtt aatatatatt tatcattata ttatataata atatagatag ttactatatc
    61261 ttataattag ataaatcata attatatatt attgttaaaa ctcaattata taatttttaa
    61321 taatattatt ttaggaggta aaaatgataa acgatattaa aaataaattc aaaaattaca
    61381 aaccatatat aaatggatac aagaatatga agagagcatc tgttttaatt ccaatagtag
    61441 aaataaataa cacacactat atattatttg aagttcgctc aaaaaatttg aagcatcaac
    61501 ctagtgaaat ttcttttcca ggtggtaaaa tagaatcagg tgagactcca tatgaagctg
    61561 ttattagaga aacttgtgag gaacttggaa cttttagtga caatatagaa gtaatatcaa
    61621 gtcttgacct ccttataaca ccagtaaagt ttatcataca tccatactta ggatatataa
    61681 aaaatattaa taatttaaat ataaacaagg atgaagttga ccatactttt ttggttccta
    61741 taaaatatct tttagagaat cctccaaata cttatagtaa tactgtaaaa gtttttccag
    61801 acgaaaatct accatatggt tcaattccaa accaaaaaga ttataaattt gaaagtggaa
    61861 gttatcctat tctgttttat aaatataaag attatgtaat ttggggaatg acagcaaaaa
    61921 tactagaaaa ctttttaaat tttttatcag aataacactc ataataaatc atcaaaactt
    61981 ttacataaga aatttataaa agtttctaaa tttaacaatt ctaaaatatc aataactata
    62041 ttttgtagca cttttttatt ttattattgt ttgaatattt gatggttttc aatgcaattt
    62101 caacataaat actatgtatt agtgtatact gttgatgaat taaagtatga taatctattt
    62161 aataaagtat gaagtaaatg attttaatgt gcctttatgg taaaattact aataagtaat
    62221 aaaattaatt aaaatatatg gaggtgctta taatgtttgc tgtaggattt gttgttataa
    62281 ttgcacttgc ctttttcatt ttaagtgtac tattatttaa tggaaaagcc agtatgctac
    62341 tagcaggtta taactctatg agtaagaaag aaaaagcacg atacgataaa aaaaaattat
    62401 gtagaagttc tagcattgtt acttttattg tctctataat gctatttatt atggcgtttt
    62461 tgggatatag aatagagagt ggtcaaatgg acgaaaaaaa aatggttccc ttttctataa
    62521 tatttataat agtcatactt tccagtgtat tttttaatat cctctactct aacaaaaaat
    62581 gtaaaaaata aatagttgta agttgagcag ttaattataa aagattgact gctttttcat
    62641 gtatattgac tactcttatt aaatatttta acatttaaaa atctatgtaa aaataatgaa
    62701 tatagtacaa acttctaata atgattttac ctttgtggtt acagtccact atatataatt
    62761 taatatgata acagggaatt actaatgaca actaggtaag cttttataaa atataataaa
    62821 acaaaaatag atgtacaatg aaattatatc ttatatcaaa tttattttta ttaatagcaa
    62881 aaacttacat tagcataaca tatgacaaat tcgcttaaaa taaaaatttt taatataatt
    62941 tgttctatag tacatctatt ttgattagtt tacataattt tattattttg tacaatatta
    63001 attatttact aatatcccat ttaatgaaaa agttctaggt tcagtaattt ttaccataac
    63061 taatttacca attaaatcat catttccacc ttcgaaattt acgagtttat tttgtctagt
    63121 tctaccagca aacttatttt cattattttt acttcttcct tcaactagaa cttcaactat
    63181 tctatcttta tatccatcat ttatttctgc agaaatccta tttacagctt ctaacaccct
    63241 attaaatcta tcatgcttta tatcttctgg tatttgattt tccattttag cagcaggagt
    63301 tccctgtctt ttagaataaa taaatgtaaa agctgaatca tatctaactt tttcaaccac
    63361 atctaaagtg tccaataaat cttcttctgt ttctcctggg aaaccaatca ttaagtctgt
    63421 agaaaaagca atacctggaa cttccttttt agctttttct attatttcta aataatattc
    63481 ctttgtataa tgtctattca tttttttcaa aaggctactg cttccacatt gtattggtag
    63541 atgtaaaaac tcacacacct tatcacaatc tctaattgcg tatattactt catcagatat
    63601 atcttttgga tgagatgtca taaatcgaac cctttcaatt ccttctatat cattcacttt
    63661 tcttaaaagt tctgagaatg aaactggatt ttcaagtgtc ttaccataag aatctacatt
    63721 ttgtccaagt aaagtgattt ctttcgttcc atttgcaaca agctctttta tctcgttaat
    63781 tatatcttca ggagttctac ttctttctct tcctcttgtg tatgggacta tacaatatgt
    63841 gcagaaatta ttgcatccat acattatatt tacaaatgct tttaattcaa attttctatt
    63901 acttctaaga ccttctatta cttctccatc cacatcccat acatccacta acattttgtc
    63961 agaatttatt gattctgtaa gtaattgcgg aaatttatat agattatgtg ttccaaatat
    64021 aaggtctaca tgtttatatt tttttcttaa ttcctctaca acatgtggtt gttgcatcat
    64081 acatccacat acagctattt tcatatctgg attttttcct tttagatgtt ttaattgtcc
    64141 taagttacca tacactttta gctctgcatt ttctctaact gcacaggtgt tatatattat
    64201 taaatcactt tcttcaacca tcattgacat ttggtatccc atctcttcta acattgaaca
    64261 taatttttct gaatcatgtt cattcatttg acacccgaag gtttgagtaa acacgagttt
    64321 tctctttcca gttctgttga agtattcttc attttgtctg tgtatttgtt ctatatattt
    64381 atcttgttct tgtattttct ctataggtat tgttacttgt tttcttttgc tcacgtctat
    64441 tcctcctagt taatttctta tattacacat aaccttaatt atatcaaata agaaaaatct
    64501 tttaaagata ttattatttt tctagttgtg ttttaatagt aaatctaatg atttatatat
    64561 actatatttc taaaatataa aatcatataa ttattataat aataaaaaga tgttttaaat
    64621 taaaacttaa aacacctttc cttaaataaa atatatgatt tactattaaa tacaattaca
    64681 tctattcatt ttcaattaaa taacaatcat ttaatattaa atattgatct tcctcaaccg
    64741 ttatatatct tcttcctgaa aaagtatcat tagtaactat tccctctgca ttacctaagc
    64801 tatcatttct aacttcataa tatgcatcag aagaatttga cattataata tattctccag
    64861 caggaatttc taatccaatt ttatacatac catttccaaa cttaccattc ttggccttct
    64921 gggctttagc atactttgct aatgtcattg ttgaatcctc aattttaata tattgaccat
    64981 tctttaaggt gatatatcta gtcccactaa aaatatcatt tgaaagtata ctatcagcat
    65041 tacctgtact atcacttgta acttcataat aagaagcata acttcctgag tttgaagtta
    65101 ttaagtattc acctgctgag atatcttttc caaccttata cattccatct tttatagtct
    65161 ttgtagtagg tttaacattt tttacaaccc cagtattaat atctccaatt ccatttgtta
    65221 tatttaaaca ctgttgtact atatttgaat ctatatatcc tatagaagtt atcttcttag
    65281 cattttttaa aatgctttta ttgctaccat cgttaactaa aaccattgga ccatgttttg
    65341 ataaagaaga tcctacaagt gcatttgtta attcataagc tccagctata taaaactctc
    65401 tagcatcctt ataaaactta tttattattg ctttattagt ttcaaaacga gtactccccc
    65461 ctagtctagt agatttagta ttgtttacta aagtggtact cattgaagct gttcctccta
    65521 ttacataaga ctttaaacca ctagttgaaa aaggtatact ttgtccatta gtaagaatta
    65581 ttggtgcttt atctcttgct gctacagatg caatacttat agcatctgct tctcctttat
    65641 atgcattggt tagcataaca gtattgactt tttttattga atttatttct tttgcaacat
    65701 tataacttgt ttttattctg tcatttccct taattcttac aactttcatt ttcttagatt
    65761 ttaatgaatt ttcgacagat gtactaatag aatatgttcc tccaattata taaacttttg
    65821 atacattttt taatcttgca gatgtctcag ttggtatagt atttttttca gttaatagta
    65881 taggggcatt taaagctcct gctagtccac ttgcacttaa tccatctgca atagagttac
    65941 tagtattaat taatatagca gttttatatg cagttttata tgcagtttta tatgcatttt
    66001 tatctgctat tttacctgct atttcatact tattttttcc ttgtattttt tctacagatg
    66061 atattgcatc tactaattga atatttgcaa atacaaaaga aatacttaaa gtcaatgtta
    66121 atattctttt atagaatttc ataataaaat tgtccccctc ataataaatt tttaatatat
    66181 aaatacatat tcttaaatta gttatgtact taacaaactt atgtaaaatt gcaaattata
    66241 ttaagtatat tacaaataaa tattaataca attattcatt tagctataat tgtatttaca
    66301 tttatattaa aaatcaacta gatttgtata aatacttata attatatttt tattcttaat
    66361 atttttttta ttatgttatt ttaatagatt tatttttctt ttttaagcat agagatgtat
    66421 ttttccatat attctatttc tattatagtt tcgcttattt aattcaccca aaatttcact
    66481 taatattaga attttaaatc ttttactaaa acagactttt atagttctat taaaattttt
    66541 tactaaactt tattttttac tatgaattat ctattttttt ggctaaattt aagcaagttt
    66601 ttcacaaaaa atatatacat tactatattt ttaaaacttt ataaatatat aattgattta
    66661 attggaaatt ttagtgtatt caaaaaatga gaaatcagag gagattaata taaaaattta
//
LOCUS       DAEPHU010000013        65677 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 01A10CD0081
            SAMN05941466-rid12468953.denovo.013, whole genome shotgun sequence.
ACCESSION   DAEPHU010000013 DAEPHU010000000
VERSION     DAEPHU010000013.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941466
            Sequence Read Archive: SRR6291087
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 65677)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 65677)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068158.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 22:43:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,892
            CDSs (total)                      :: 3,805
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 87
            rRNAs                             :: 8, 1, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 55
            CDSs (without protein)            :: 55
            Pseudo Genes (ambiguous residues) :: 0 of 55
            Pseudo Genes (frameshifted)       :: 21 of 55
            Pseudo Genes (incomplete)         :: 28 of 55
            Pseudo Genes (internal stop)      :: 16 of 55
            Pseudo Genes (multiple problems)  :: 8 of 55
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..65677
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941466-rid12468953.denovo.013"
                     /strain="01A10CD0081"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            complement(<1..907)
                     /locus_tag="KR231_000902"
     CDS             complement(<1..907)
                     /locus_tag="KR231_000902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exonuclease domain-containing protein"
                     /protein_id="HBH0003307.1"
                     /translation="MFILKRVYIDFEMNMPNSKSKRAVFNSDIIAIGAVMYDEKTKNI
                     DKFKSLIRPVSNEELYPHIQELTHISSEELKSAPSYEEVMRKFKKWLGIFSDIKGIYT
                     FGNLDLTCFNNTDMRSAKKNNHPRFVNNIRDLFVDIKEKYINCGMRCMNYISLKNLLE
                     FVNLEFSGDAHDPLNDAYNLFILDEAITNNVDIQNLLIIRDIIRPPFNDINSNLDNCF
                     NKFKESLYKKEGNYNIVDFSVEIIKTVRMYLLTIIDVNIQNLEIMKDISKKMDTIDKL
                     KDIEEGYFYLLEDVYFDMKDVLEDLM"
     gene            complement(946..1806)
                     /locus_tag="KR231_000903"
     CDS             complement(946..1806)
                     /locus_tag="KR231_000903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011986089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 2-thiocytidine(32) synthetase TtcA"
                     /protein_id="HBH0003308.1"
                     /translation="MSELSGKGCEIIVPFEERLPVRDIEKSIIKKYRKNLWSKFMKAI
                     RDYKLVEEGDKIAVAISGGKDSILMAKMFQELKKHGQVNFDVEFIAMDPGYHANIRQL
                     LIDNCEYLNIPIHLFDSRIFEIADEIAKDYPCYMCARMRRGALYSKAEELGCNKLALG
                     HHYDDVIETTMLNLLCAGNFKTMLPKLNSTNFEGIKIIRPLYYIREEHIIRFIQNSGI
                     WPLNCACMVAAKKTGNKRYEIKDLIKSLESNFKNVEKSIFKAAENVNLDSVLGWQKDG
                     EKHSFLENFE"
     gene            2075..2284
                     /locus_tag="KR231_000904"
     CDS             2075..2284
                     /locus_tag="KR231_000904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="spore coat associated protein CotJA"
                     /protein_id="HBH0003309.1"
                     /translation="MENKTRDIKKNCGPSLARPYINNQIFTEMYCLSDALKFGTIFPE
                     LNLLESEMYNKELYAKPKKYRGGRR"
     gene            2284..2550
                     /locus_tag="KR231_000905"
     CDS             2284..2550
                     /locus_tag="KR231_000905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="spore coat protein CotJB"
                     /protein_id="HBH0003310.1"
                     /translation="MKDSSRAELMRKVQETSFACVDMNLYLDNHPDDKNAINTYNSLC
                     NQFAQARYAYENKYGPLTNFGYAPSRCPWQWADQPWPWDREFNY"
     gene            2579..3151
                     /locus_tag="KR231_000906"
     CDS             2579..3151
                     /locus_tag="KR231_000906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000265278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="manganese catalase family protein"
                     /protein_id="HBH0003311.1"
                     /translation="MWIYQKTIQHPVNIKTCDPRMAKFLITQFGGPNGELAASLRYLS
                     QRYTMPTGNMRALLTDIGTEELAHVELICTMVYQLTSDASPEELKAAGLGSNYAQNGY
                     GIYPTDSNGVPFDVRPIAVMSNPVTDLHEDMAAEQKALATYYQLINLTDDVDVIDVLK
                     FLGQREIIHYQRFGEALMDAYELEESQKMF"
     gene            complement(3386..4576)
                     /locus_tag="KR231_000907"
     CDS             complement(3386..4576)
                     /locus_tag="KR231_000907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SH3 domain-containing protein"
                     /protein_id="HBH0003312.1"
                     /translation="MNFNQKRIAASIMATAIIMPTMGNLAYANESEVESVSIESRTIT
                     GNAVNFRKGPGTNHESMGKLYKGDKVEYVGKEGSWVKVKYNGNTGYVHGNYVAINSLG
                     SSNESSDTSVKSTKVVTAKGLNFRTGPSTSSSKISTLGYGTEVGYISESNGWSKISSN
                     GRVGYVSSKYLGTSVNDSTNENAENSSNDLVKGTKVVTAKSLNVRTGPGTSHSKIATL
                     SYGTEVGSISESGGWTKISYGNQTGYVSSQYLAEKGSVDTSIPSYSTNSPSQGADSVI
                     SFAKTLLGKPYVWGAEGPNSFDCSGFTQYVMKKSVGVSIPRVSRDQSKYGTYVNRGDL
                     RSGDLVFFDTQGSNNGSVSHVGIYIGNGDMIHASSGSSKKVTISNINSSYYSSRYVNA
                     RRVL"
     gene            complement(4836..5267)
                     /gene="dut"
                     /locus_tag="KR231_000908"
     CDS             complement(4836..5267)
                     /gene="dut"
                     /locus_tag="KR231_000908"
                     /EC_number="3.6.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454700.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dUTP diphosphatase"
                     /protein_id="HBH0003313.1"
                     /translation="MYNLKVKKLNDDAIIPNFAHKGDAGMDLYSIEEVVIPPGETKLI
                     KTGICIELPTMTEAQVRPRSGLALKHSVTVLNTPGTIDEGYRGELKIILINHGKNDFK
                     VEKHMKIAQMIVKPIYDINIEEVKELSDSERGKGGFGSTGF"
     gene            5380..7608
                     /locus_tag="KR231_000909"
     CDS             5380..7608
                     /locus_tag="KR231_000909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IA DNA topoisomerase"
                     /protein_id="HBH0003314.1"
                     /translation="MKLVLAEKPSVAKTIASFLGAKTRQDGYFEGNDYIITYAVGHLV
                     SLYDMKDYDKDKYSGSWKMNNFPFVPEDKFKFKIDSSKTKQFNTVKKLLNRKDVEYVI
                     NATDNDREGELIAFLIFLLAKNKKPVKRILVNEWTPEDITRGIKNLKDEDEMRNLQAA
                     GYTRLITDWLIGINFTSVATLKYGNGKLLNIGRVILPTVKLVYDRDMEILNFVPKTYY
                     EIEGHFKAEAGEYKGKYVKGKESKFDTLEDANKIIASITSETGKILDKKVTMSKEYAP
                     KLFSLTSLQGYITSKYSNFTSDKVLNVCQSLYEGNGKGGYITYPRTDSIFLEESLASK
                     ASQTLDKLKVGLEYENKIKFSKTKRVFDSSKVDSHSAIIPTYIIPKSLSKDEQLVYDA
                     IKDRFVANFMPPAEYENTEIKTEVDNCTFLTKGKVLKSKGYLEVYNKEEKNDLLPLVN
                     KDDVVDVLEIKPLTKQTTPPKPYTEDTLLKAMKNCGKNVPEEDTTVLSGYSIGTSATR
                     ADVLKKISQVGYVKKKGKSYSITDLGKNLVEIFPVKDLFDVDYTGKLEKSLSDIQKGK
                     YTRKEYLTNIISFIYQNVNIIKQDASKNINTEAYTFDSKTKKFTKTKEKKQKKDVTNT
                     EKEVAISKDSNNKKEVKNGDENQSLGKCPICQGDVLEFDKGFACKNHKECKFVIWKND
                     KYLSLYKKKVNKTMVKNILKKGETKVKSLTAKNGNKFDATLKYDKNPDTGYFNWKIEF
                     DN"
     gene            complement(7719..8204)
                     /locus_tag="KR231_000910"
     CDS             complement(7719..8204)
                     /locus_tag="KR231_000910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HBH0003315.1"
                     /translation="MDNNNILKIADSFLDFLFVLENNIFKESDLLKKFQNNSDIMKAY
                     FEECPMAPSHAKVILYLMTSNSSSISQIASNLGILKSNMTPIIDRLVEHGLVNKFPDP
                     KDRRILRVELTDKAFKLFDAVKAILKESLVKKLSNLSEEELTLLDEHTLKLSEIVKKL
                     G"
     gene            8456..9679
                     /locus_tag="KR231_000911"
     CDS             8456..9679
                     /locus_tag="KR231_000911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="efflux RND transporter periplasmic adaptor
                     subunit"
                     /protein_id="HBH0003316.1"
                     /translation="MKRYLIVFLMCSSLFLVGCGKTEESEPEKPIAVSVQKAIGGEIE
                     NTNSFSGTTKVKDETAVTAQTVGTVQEVYVKLGQNVRKGDELLSISSPELENSVKQSK
                     ASLDLAKASYSSATGGSLEAQVNQAKTALDNAKIQYEESQRNYDNNKILYEQEVISLD
                     QFKKIEFSLEQTKQQLDSAQRAYDTATSKSIPQAKALAKKQLDQAQVSYNLAMSNLDK
                     LTLTSPVDGTITAKNFDSKEMITQSQPAFIISNPNILEVDLNVAESDIGKFKKDGNVD
                     VIIEDQRILGKIDYVPSVVDPQTSLYPVKVLVNNTNNKFKAGMSAQVNLSVEKENGAV
                     TVPKKAIFEENGKKYVYIATKDNIAKKHLVQTGIVTEDKIEIKSGVSDKDTVIIGGIS
                     LISDGTKIFPVEKEK"
     gene            9683..12817
                     /locus_tag="KR231_000912"
     CDS             9683..12817
                     /locus_tag="KR231_000912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="efflux RND transporter permease subunit"
                     /protein_id="HBH0003317.1"
                     /translation="MNLTQTSVKRPLTIIMVFLVLIVFGGIGYKKMSINLMPDIEIPV
                     VMVMTTWTGAGPQDVDEQVSQKVDESLSAVSNVKSTISSSQESVSMVVAQFEFGTNLD
                     EIMNDVRSKVDALQTSLPDDAAKPTVLKLDMNAQAIGQLVISGGNENSSQALRKYAED
                     VIQPKIESIDGVTSADLKGGEKAQVNVIADPAVLSNYGVSLSTIKGVLSSSNKTFPYG
                     SITQGEDKIVLRAIDKLESLDDIKQIQIPVKGGNTVRLDNLCSVDYGYADKDSIYRYN
                     GKDSLVIDISKQQDANTVKVMQSAYKYVDELNKENPQFKIKIANDTSSYISESINSVM
                     SNLLISAVIAFIVIFAFLKSVRASLVVAVAIPISIIGAIAILYFTGESLNLITASSLV
                     ISVGMVVDNATVVIENIFKYRKSGRLSLDDCAIEGTRTVTNAILASTLTTIAIFLPIM
                     FTEGIAKITFGALGKTLIASLAFSFIGAITLVPSVFAKLSREKNSQKMQEKDSPIFDK
                     VSEAYKKLLSVCLRHQRLVVISSLLIFVASLFGMGFIGMDFMPAADKGELSISIELPK
                     GLSLESNDYYVSMTEKKVSDIPEIKTLITTLTSDSNNSKASIAIELESQKNRKRTTDE
                     IEKEIIDRVATVPDCKINVSQNSSVMGGAGGADFTLEMKGPDLDVLKILGKEAEKEFS
                     SIKGFRNVETSLTDTTQEAQFTIDKHKAQEYGVNTAEIAGMLRTAINGDSVTTATIDD
                     YKVDVNLKFKADTIDSLEDIKQLKVNSATGKEVPLGAFSDIKMADGLQSISRTDGDFS
                     VNITATLDNLDAGTATKLALEKTNKMVIPKDYSIGVGGETEMMNESMASLGFSMVIAI
                     ALVYMVMVAQFESFSKPFIIMFCVPFAFVGVVLSLLVSGQSLSTVGMLGIILLIGIVV
                     NNGIVLIDYIEQLRKTNRNNDLIGLVSIGCAARLRPVLMTTATTILGMLPTALSLGEG
                     GETMQPLAIVIMGGLTVSTLITLVLIPTIYLIFDKWENKFSDKMPKIFGKITDKIGSI
                     KRKIIKKPKLKAKV"
     gene            12851..14149
                     /locus_tag="KR231_000913"
     CDS             12851..14149
                     /locus_tag="KR231_000913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TolC family protein"
                     /protein_id="HBH0003318.1"
                     /translation="MSKIVAISCGVGIITANLIPVYADNNTSSINKVDNSILSDSNKR
                     TSEKEILTAREAVSAALKNSEKLKMKSEEIKMLKEKLEVQDEFDSFTGSDNSFPYDQI
                     GLLKNQSEQAKGFMEDQIANDITNKFNDLVSRENELDKIKNNLEIKTKEIKDMKLKKD
                     LGLVTSLETESAELELQTLQNTQKAKLQELKNNQDYFKLLTNIDLNNYQLDKEYRFES
                     FRVGGSVDSYMEGKVNEYLKYDQLILERTEESFNDKDENKADLPDRPNLTRPVAPTKP
                     EQGNLTDDEYKVLMDKYEKDYDRYKKEVEAYNLERQTYAAGLTTYANYLQQKFNTENG
                     LVTLEDSKKALKKGLIDSYAQLLALEDTIQITKKQLDLSEKQLKNTKLRYDLGLITLT
                     DYKKQVVSNEDAKNSYDTLIVNYNSLKNGIEKPWILNTGK"
     gene            complement(14438..14683)
                     /locus_tag="KR231_000914"
     CDS             complement(14438..14683)
                     /locus_tag="KR231_000914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ribbon domain-containing protein"
                     /protein_id="HBH0003319.1"
                     /translation="MTKCPKCGKEVSSRPGSICPRCGFKVADESLKIRCPEPSCRALV
                     SRKLDYCPKCGCKLRGYNISEFVNMVRCKIDETFDKK"
     gene            complement(14897..17524)
                     /locus_tag="KR231_000915"
     CDS             complement(14897..17524)
                     /locus_tag="KR231_000915"
                     /EC_number="2.7.9.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate, phosphate dikinase"
                     /protein_id="HBH0003320.1"
                     /translation="METKYVYSFGEGSKDMKSLLGGKGANLAEMTKIGLPVPPGFTIT
                     TEACNDYYVNNESIRAEIIKEIEEHLATLEKDLNKTLGCNKNPLLVSVRSGAVFSMPG
                     MMDTILNLGLNDNSVVGLAEATQNERFAYDSYRRFIQMFSDVAMEVPKYKFENVLDRV
                     KEAKGYTVDTELTTDDLKEIVKEFKAIYKKEIKNDFPQDPKEQLMLAIEAVFRSWNNP
                     RAIVYRKLNDIAHNLGTAVNIQSMVFGNMGETSGTGVAFTRNPATGENKLFGEFLMNA
                     QGEDVVAGIRTPQNISTLADVMPAVFDEFVKITHILEGHYKDMQDIEFTIENERLYIL
                     QTRNGKRTAAAAINVAVDLVEAGIIDEKEAIMRIEPNQLDQLLHPKFEDKALKEAKVI
                     AKGLPASPGAASGKVYFNADDVVKANEKGEKVVLVRLETSPEDIEGMVKAEGILTARG
                     GMTSHAAVVARGMGKCCVAGCGEIKVDEFNKEIRALDDVVIKEGEYISIDGSTGNVYL
                     GDVKKTEVSLTGNFEKLMNWVDKHKCMMVRTNADNPRDARAAIEFGAEGIGLCRTEHM
                     FFDEARLPAVREMILSNTVEQREKALEKILPMQREDFVELFKVMDGKPVNIRLLDPPL
                     HEFLPHDDETIEELSKSMGIKVSDIKKRIVDLDEFNPMLGHRGCRLAITYPEICVMQS
                     KAIIQGAIEAIKAGVKVSPEIMVPLVGEVNELKIIRKMIVETVDAIIKEEGIEVPYTV
                     GTMIEIPRACLTADEIAQEADFFSFGTNDLTQMAFGYSRDDAGKFLGQYVDEEILEKD
                     PFQVLDQNGVGKLVKMGAKLGREVKPELKLGICGEHGGEPSSVEFCYSVGLNYVSCSP
                     FRVPIARLAAAQASIKNPR"
     gene            complement(17585..18427)
                     /locus_tag="KR231_000916"
     CDS             complement(17585..18427)
                     /locus_tag="KR231_000916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="kinase/pyrophosphorylase"
                     /protein_id="HBH0003321.1"
                     /translation="MLVKNLIIYAVSDSVGETAQQVAKACMSQFYVNETYEIKRFPYM
                     INKGVLLETLENAKAENALIVYTLVDEELCSIVERYCEREGLSCIDLMTDILREISKR
                     TGRKPKREAGIIRKLDESYFKRVEAIEFAVKYDDGKDPRGVLQADIILVGISRTSKTP
                     LSMYLANKNIKVANVPLVPEIPIPKEVFEIDTKKIIGLTNSPEKLNEIRTQRLKALGL
                     SSKANYANLERILQELDYSEEIMKRIGCPVINVSNKAIEETAGIILDIMKENGLKIYK
                     EIEI"
     gene            complement(18434..19072)
                     /locus_tag="KR231_000917"
     CDS             complement(18434..19072)
                     /locus_tag="KR231_000917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBH0003322.1"
                     /translation="MIIIQLNERQLKIIDIVKENEPITSESIASSLNVTRATLRSDLA
                     ILTMTGILDARPKVGYFYSGVSEINLIGKSVKEKTVEDIMSMPVLAKKDESIYDVIVT
                     MFLSDVGSIVIIDENEELCGVVSRKDLLKATIGGSDINKMPIGMIMTRTPNVVTLTKG
                     ASVLLASRKIIEHEVDSIPIVEYKGEDKNHMRVVGRISKTNITKLFLEIVDN"
     gene            complement(19508..20800)
                     /locus_tag="KR231_000918"
     CDS             complement(19508..20800)
                     /locus_tag="KR231_000918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)-dependent oxidoreductase"
                     /protein_id="HBH0003323.1"
                     /translation="MLDLNRKLAKLEEEGKKIKVALIGAGHMGNGMVSQMANMKGIEA
                     SIVVDINLELAHKAFTDAGIDEEIIDNVTNEKDAEIKLQEGKVLTCNDFLVACKTKSI
                     DVVIDATGGIAIGAEIALNSILNKKHIVMLNAETDCVVGPILKKLADDAGVIFTGSAG
                     DEPGAVMELFDFADAMGFEVRVIGKGKNNKLDLDCNPDTVREEAERKGASPHMIASFK
                     EGTKTMVEMALMCNATGFVPDVRGGHGIEATVNEVPKKYALKSEGGVLDNYGVVDFVN
                     GIAPGVFVVVAHKLKAVNDELKYLSMGDGPNYILYRPYHLCSLETPLSAAMAVLDHKA
                     TIVPKAGLVAEVMTIAKKDLKKGEFMDGYGAYTCYGTIEKYDVAKAMNAVPIGLISKK
                     TKVVKDIKKGEVITYDMVEIEKDTTLYHLRQLQEKIFG"
     gene            complement(20837..21193)
                     /locus_tag="KR231_000919"
     CDS             complement(20837..21193)
                     /locus_tag="KR231_000919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIA"
                     /protein_id="HBH0003324.1"
                     /translation="MKYEVKISGIGSLVKELMDESNCLIIYDETINDDDLKDISVIHS
                     IATLKSDVEIGDTLTIGNRDYCIVSVGDIAQKTLREIGHCTIKFDGKCEVNLPGEIHV
                     EIGNPDITIGDLITIS"
     gene            complement(21228..21587)
                     /locus_tag="KR231_000920"
     CDS             complement(21228..21587)
                     /locus_tag="KR231_000920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0003325.1"
                     /translation="MKLLVILFVAYILNTIFIMKQNKLYFKTLNRAKKKGDIVSTGKK
                     KSYFSKGSIAIISSDSDGFIKFGEILKGRTVMAKFKEIEEIEGLDIYSAEQKFKDEES
                     IVQAIKFIKEKINVSFN"
     gene            complement(21656..23629)
                     /locus_tag="KR231_000921"
     CDS             complement(21656..23629)
                     /locus_tag="KR231_000921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HBH0003326.1"
                     /translation="MSVTEKIPSIDRKIFKILIMCSKKEFVSINSIANELNVTTRSVR
                     TYIKQLNKDLGNDIAVIKYIKGQGYKLEIKDEQILNKIIDMNRKNVFSLNSKEDRVEF
                     ILNYLIELDGFITLDSLADEMCVGRTTLVNDFQYVEKVLASYNLNLIKKQNTGMKLNG
                     NELDIRLFILNQLYKNSRKDFSNSKYFKGIKKEEIINLEEKLLTLFKKNNFYVTDEML
                     REVINYIVVLVYRVKEEKKVKDYDVKFDLLKSYDEYFIAREIKHIISGMFECTLNDEE
                     IIYLTIPLVSGNAPASECALNSSRISKNIDELMENIFNQIYVDMGIFINEDELRVGLG
                     YHLSFTLNRLLFNIKLKNVLLEEIKQNYILPFKLAQIAGKVIEKKYNLEVSEDEIGYI
                     AIHFSGYLERNSSRFYSIKKIAIICSTGLGTAKLLKIRVEKLIGNNPKIDTLSSFNLR
                     NINLDEYDIVFTTIDLDTSNINTIVLKINTIFDENKLREQLKTVLCLREGNIDTTNST
                     NLLINNLLDEDKFMILNEKTILASLEKMMDHLMDLGCIDDKFRKNIVNREEKSPTVFD
                     KGLLFPHSVNEKSDKFLMAVGILEEPIEYANRSIKIILMTMFPCENKIDSDLLVKIYE
                     EVLKIGQDVKLTNKISKCRTFLEFKKVLLKNLI"
     gene            complement(23851..24864)
                     /locus_tag="KR231_000922"
     CDS             complement(23851..24864)
                     /locus_tag="KR231_000922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIB"
                     /protein_id="HBH0003327.1"
                     /translation="MEENKILKIEKGTSGWGGPLYIKKEGNRNKILSMTAGGIHEVTL
                     KIKELLGCEIVDGFKTGVSDEEVAVVIIDCGGTARCGVYPKKKIPTINVNPVGKTGPL
                     AKFITEEYYVSDVNPNCISVVDGEDMPQKSQENKSENKSSIRKPDNYDEVKSKAQGEY
                     AKKNIILSIGQGAGQVVSKFYDAGRDTIQMVMNNVIPFMAFVSMLMGIILASGLGDWI
                     ARVISPLAGNIGGLLIISVICTLPFLSPILGPGAVIAQVVGTLVGTQIGLGAIPAYLA
                     LPALFAINGQAGCDFVPVGLSLGEAEPETVEYGVPALFYSRLITGPIAVIIAYGVAVF
                     ALR"
     gene            complement(24877..25422)
                     /locus_tag="KR231_000923"
     CDS             complement(24877..25422)
                     /locus_tag="KR231_000923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIC"
                     /protein_id="HBH0003328.1"
                     /translation="MENVITGLSKGAEWFIGLFQKGGEQFIGLVSGTLPTLIVLMVAI
                     NSLIKIIGEERVNNWASKLGKNSFTRYILLPLVSVFFLGNPMCYTFGRFLKEEHKAGF
                     YDAAVSFVHPITGLFPHANAGELFVWLGISAGLTTLGKETTTLALWYFIVGLIVIFIR
                     GIVTEKMYAFLTRKNRATNKA"
     gene            complement(25798..26667)
                     /locus_tag="KR231_000924"
     CDS             complement(25798..26667)
                     /locus_tag="KR231_000924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HBH0003329.1"
                     /translation="MDYLKYFKKAVMYIENNLHENITVNDVAKETGYSYYHLTRLFKS
                     MFGESVGSYIKKRRLVSSTKELLYSDKKVIDIAIGSGFESSEAFSRAFKSIYKVSPIE
                     YRKNRIDVFVGKKKKLELDFMRHLVGNITIKPVIKEIEKIKVIGIKDKVILENNSLPD
                     LWEKFRKVHHIVPNTLPSKRVFGICEAISEIHLVSESMEFNEIIGLEVNSYDVIPNSF
                     VSKTIKEGKYAIFTHTGSLDNLDKTYEYIWGTWFLSSKEELDIRDDFEVYDERFLGPS
                     NVNSQIDIYIPIK"
     gene            complement(26819..27934)
                     /locus_tag="KR231_000925"
     CDS             complement(26819..27934)
                     /locus_tag="KR231_000925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="linear amide C-N hydrolase"
                     /protein_id="HBH0003330.1"
                     /translation="METLEVRNIELSGTNYEIGYRLGELVANMPEIIEGQINKSNLVS
                     KKEEKEMIELFDKYCPGLNEELQGFADAIQVNCNQILYYTMTYLKPGCSQVALAPELT
                     ENGHVLFARNFDFSHNMEDFVLCKTKVNGKYAHIGTTVMQFGRGEGMNECGLGVSQSS
                     CGIPVGNSDGLRKPAIVGLQFWAVIRYLLENCKDVDEALEYLKDMPIAYNINLLLADK
                     SGNIALVETLDGKKEVNIINSLESKREYFLHSTNHTHIDKLHKLEPQSMKNSIHRYKL
                     IKEYINKSKKIGEKELMNLLSSKYPNGLSCNYYNDFFGTLKSIVMDLNIGKFNILWGG
                     LENKWESYYLKNDIKSITQRININIEKAPSDFFDFIE"
     gene            complement(28170..29306)
                     /locus_tag="KR231_000926"
     CDS             complement(28170..29306)
                     /locus_tag="KR231_000926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallopeptidase"
                     /protein_id="HBH0003331.1"
                     /translation="MKERIIQVADSKKEKILGLCQSLYDEPEIALQEYKSAKKISEFL
                     REEGFDVEENLAGMATAFKATKKNGDGPKIAFIAEYDALPGNGHACGHHLIASMGVGA
                     GIALSSILDTYKGEVSIIGTPAEETGDGKPYLIEHGVFDGYDAAMMIHPNSKTCVTPE
                     IIAIGGLDFIFTGKASHAGAKPYNGINALDAVVLLYNNINALRQQLVDGTRIHGIILE
                     AGTAANVIPDMGKVRLEIRAKEQNYFDEVVEKVKNCARGAAIATGCELEFYHFEPTCQ
                     GLNENKVLVDIFTKIMEEFGIYEDEQVMLGSTDMGNLSQIMPCIHPLMKFSENGEELH
                     TKEFLEASINSYAKDRVIDGIKILALTGFNLFENPELLKKMKEE"
     gene            complement(29362..30825)
                     /locus_tag="KR231_000927"
     CDS             complement(29362..30825)
                     /locus_tag="KR231_000927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine:cation symporter family protein"
                     /protein_id="HBH0003332.1"
                     /translation="MTDLVNTINGIVWSPVLVAMCLCIGLYFSLKLKFFQIRDVKEMF
                     TLLLEGDSSHVGISSFQGFATSMAGRIGTGNIAGVAVAIAMGGPGALVWMCIMATLGS
                     ATAFVESTLAQIYKDEHDGQYRGGPPYYFEKGLGWKKCSVLFSIVAIISYTFFMPGTQ
                     SNTLYLAMNQAFGFSKMTIAVASSIALAIIIFGGIKRIGLFAEKVVPIMGGAYLIMTL
                     VIIITNISLVPEAIVTMFKSAFGFGSVFGGMLGSAISWGVKRGIYSNEAGEGSGTYGA
                     AAAEVSHPAKQGLVQAFSVYVDTLLICMATGIMIVITGMYNVTGVCTALPGVEPGPQY
                     VQSAINTLHPQLGDIFIAIVLLLFTFTTLLAFSYMMETNVSYLVTRIKAEKHEKYIIN
                     VCRFMLIACAAMCCFIEPLTSWALGDICIGVLTYINLIAIFTLKKPAIKAYYDYIRQK
                     KMGIKRSDRTFNPIELDIRNAEFWENRYLKEDKHELN"
     gene            complement(31470..32729)
                     /locus_tag="KR231_000928"
     CDS             complement(31470..32729)
                     /locus_tag="KR231_000928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBH0003333.1"
                     /translation="MGEKENGIKFGKLMFQLVIIAISWELVYIIPFIQYTLYDPILKA
                     LECTNTQLGFLLTIYGLGNIFGAPIGGWLADRFDYRKIILGSVFLNGVVSFLFAFNMN
                     YPFAVATWVGCAITSLVMNYPSMVKILRVIGKDNQGKVYGFNEAMVGVSGVVMGAIFL
                     YIYTCFATPTLGMRWVMISLGILSIAMCPVLWFVIKDVDIKEEREEAGEKMSAGDFIT
                     VLKSPNTWLVGISIFCVYSFTVTMSYFTPYITSVLGGSVALSGALAIIRQHGLKLFGA
                     PFGGYCADKLKSPTKVLLPIYVFGIAVIVLFLVLPASTPMTIFIALTFVVGILGYMGK
                     GIYYAVQDEVKVPVKYSATTIGIAAALGFSPDVFQFALIGHWIDTYGNKGYTYTFIFQ
                     IAILVIGILSCLYILKVKKRRASKLEA"
     gene            complement(32753..33961)
                     /locus_tag="KR231_000929"
     CDS             complement(32753..33961)
                     /locus_tag="KR231_000929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HBH0003334.1"
                     /translation="MKYAKRMDMVKASAIRDSQKKIAQKVASGGTVISFAAGLPDPNL
                     FPIEEISEITQKVLNERGKFALAYGPTKGEDELLDLLVKRMKEEENIDTKAENIIITT
                     GSQQGIALSAMILLEKGDVVVTENPSYLGAINAFRPYECDFLGVDTDEEGMVTDDLDK
                     LLSENSNIKVIYVIPTFQNPTGKTWSLQRRKDFMEVVNKYDVIVIEDNPYGEIRFTPE
                     PLPTLKSLDTKDKVLYLGSFSKVLCPGFRVAWMCGNVDIIDKAELLKQGIDLQSNQFS
                     QVQVIEFLKKYNLNEHIEKIRAEYKKRCLLMLDAMKKHFPEEAKYTEPDGGMFIWVEL
                     PESINVDDLLDKAIDAGVAYVSGESFFANNGPKNTMRLNYTTMSEEQIVKGVEILAEV
                     IKKELNYACE"
     gene            complement(33991..34884)
                     /locus_tag="KR231_000930"
     CDS             complement(33991..34884)
                     /locus_tag="KR231_000930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional enoyl-CoA hydratase/phosphate
                     acetyltransferase"
                     /protein_id="HBH0003335.1"
                     /translation="MLKDFNNLLEEAKKLEPVIVSVAVAEDKEVLKAVKSATDLNIIK
                     PILVGDKDKIESISREIGLKGHEIIGCQNPDESVKKAVEIVKNKEAKVLMKGLVNTSV
                     YMRAILNKETGLRTGRLLSLLAVYELPQYHKLLYCTDSGINVSPNLNQKKDIMTNALL
                     TMKSIGMENPKTAILTANEMVDPKIQSTVDANLLVEMEKSGEIPKCIVEGPIAFDVAF
                     DAHAAEHKGIKSNIAGDVDLLVFPNIEAGNILGKSWLRFNKAKWAGIVLGATNPIILG
                     SRSDTAEIKINSIALACLASQ"
     gene            complement(34902..35960)
                     /gene="buk"
                     /locus_tag="KR231_000931"
     CDS             complement(34902..35960)
                     /gene="buk"
                     /locus_tag="KR231_000931"
                     /EC_number="2.7.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="butyrate kinase"
                     /protein_id="HBH0003336.1"
                     /translation="MKVLVINPGGTSTKISVFQDENEILKKNITHTREDLKNFSKVFD
                     EYDYRKQLIVDILSSENHSINSFDAVVGRGGLMKAIKGGTYTVSEEMIEDMRNEINGE
                     HASNLGALLAKTIADEIGVQSFVVDPVSVDEFDDVSRITGISDIEKASWLHALNHKAV
                     SRKIAQKLGGKYEDYNFIVAHLGSGISIVAHKQGKMIDGSGGRSDGPFSPERSGGLLA
                     YPLIELCYSGKYTHDEMVAKVSSIGGMYDYLGTKDMIEIENRIKEGDEKAKLIMDAFI
                     YQVAKEISMYGASLSGNVDRVILTGGISHSEMVVKGVAEKVSYLAPIEIVPGEMEMEA
                     LALGALRVLNGEEIAKTY"
     gene            complement(36117..36656)
                     /locus_tag="KR231_000932"
     CDS             complement(36117..36656)
                     /locus_tag="KR231_000932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416670.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-oxoacid:acceptor oxidoreductase family
                     protein"
                     /protein_id="HBH0003337.1"
                     /translation="MLNEIICAGFGGQGVLTAGKIIMYVAYKAEKKITWFPSYGNEMR
                     GGSANCNVVVSDEKIANPCVKNPDILLGMNSVSVDKYESLMKKNGYMFVNESLVSKDR
                     KYREDINVIKVPVTEIAQNLGNEKAANICMLGAMVKSLDLFTKEEFESGMCEYFENQG
                     KGKFNSKNVEAFEAGYDYE"
     gene            complement(36669..37388)
                     /locus_tag="KR231_000933"
     CDS             complement(36669..37388)
                     /locus_tag="KR231_000933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-oxoglutarate oxidoreductase"
                     /protein_id="HBH0003338.1"
                     /translation="MAKKAPAIMMCENMFCGGCGHSIVDRIIGEVLTEMDICQDTIIC
                     SDIGCNHMFQFSMNVDVVVPPHGKMGAAMAAMKRVRPDKYIFTIAGDGGAYAIGLGET
                     MSAATRNDNVIFLVMNNNMFAMTGGQMAPTTIEGQYTASTPAGRNYADHGSTFDVVKV
                     MGNLDIAYLARGTITNPKEINTTKRYIKKALEKQKEKKGFCLIEVLVPCPTNWGLKPV
                     DAMKRIENELVPKYPLGEFID"
     gene            complement(37391..38467)
                     /gene="vorB"
                     /locus_tag="KR231_000934"
     CDS             complement(37391..38467)
                     /gene="vorB"
                     /locus_tag="KR231_000934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-methyl-2-oxobutanoate dehydrogenase subunit
                     VorB"
                     /protein_id="HBH0003339.1"
                     /translation="MQSLLIKGNEALAEGAIRGGCRFYAGYPITPQSEILEMMAWRQK
                     EVGGVFIQGESEIASVNMVMGASALGARAMTSSSGPGFSLKQEGIAYWVSAGLPAVVA
                     CVQRYGIGDGFIGAGQDNYWQAVKGGGNGDYHLIVLAPNSVQENMDMAYESFELAEKY
                     MHPVLILSDATIGQMVEPCIAPPMKEYDMDKAPWAAKGTPVGEKNKVITDITYFEDQD
                     TWQKGYIEKMRKVQEDEQRWEEIEIEDAEVVFVAYGISSRIAEGAVRDARAKGMKLGL
                     IRPKTLWPYPRKAFKKLSDSLKGLVTVEMNMMAQMKEDVIIACDNRFPVYSVATAQYM
                     AEVNQLIDFAQQIIDGKAKQEEVF"
     gene            complement(38496..38693)
                     /locus_tag="KR231_000935"
     CDS             complement(38496..38693)
                     /locus_tag="KR231_000935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S binding protein"
                     /protein_id="HBH0003340.1"
                     /translation="MEKVKLSVERCKGCYLCIEACKKDAISLSDYTNKKGFVTIKVDE
                     EKCIQCGACYTMCPDLVFEIL"
     gene            complement(38976..39743)
                     /locus_tag="KR231_000936"
     CDS             complement(38976..39743)
                     /locus_tag="KR231_000936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IclR family transcriptional regulator"
                     /protein_id="HBH0003341.1"
                     /translation="MGEIINALDRALDIILLLYHEKREMGITEISKAMGVYKSTVHRT
                     LVTLENKGFVIQNAENGKYWLGINLYAIGMVVGEKMSLTEIVKPYTKKLNQEFNEVVN
                     VSILEERAQDSPRSIIIHKEYGSNQLLSVNPSVGSSSECYCSAVGKCLMAFNDSIDFE
                     KYRKTPIHKYTEHTIDNWDDMMLFLAKIKEQGYAIDDEELEHGLTCIGAPILDKNNKA
                     IAAISLSGPTIRMREGDFEYKIKRVIETAKSISELFR"
     gene            40023..41570
                     /locus_tag="KR231_000937"
     CDS             40023..41570
                     /locus_tag="KR231_000937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitrite/sulfite reductase"
                     /protein_id="HBH0003342.1"
                     /translation="MDNFKKILLNELPNFKEYSSKFLNGEINKMQYKGFSGGYGVYAQ
                     RDKKSFMIRLRVSAGVLSQYQLNKIYEIAIKHNLDKIHLTTRQAIQLHDLSINSIVDI
                     MEEGIKNDIFTRGGGGNYPRNVGLSPLSGVDPSEVFDVTPYAVATDKYFIKNATTYHL
                     PRKLKVSYSNCYTDTAHCSIQDLGFVATLKNDEPYFRVFLGGGLGKQPKVALELDELI
                     KPKDALYCVEGMIKFFMDYGNYENKNRARVRYMVESLGEELFLEKFKEYYKLEKENGS
                     LELNIEEIDYSKPGVKIDIQDSRLIPQKQDGLYTVYIHPVGGILLTKDLSTLLKELDN
                     VENPMIRLGMTEGLYILNLNGNEAKRILEISKTISCNSQLEQSISCIGVPICQMGIQN
                     SQKMLHEIIDYFRLQNNEEILNKAPKLYISGCLNSCGVHQVGSIGLCGKKKNVDGIST
                     DAFELFVGGSFEIGKTRLGKSLGDFKASDIPEMLYKISDASSGNFYEWVNSNDNILNK
                     ITDKYKI"
     gene            complement(41736..43802)
                     /locus_tag="KR231_000938"
     CDS             complement(41736..43802)
                     /locus_tag="KR231_000938"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit beta"
                     /protein_id="HBH0003343.1"
                     /translation="MKNYLLFEIGVEEMPSRFVGSTLEQLKNNLSKLFDENRIAFDKI
                     NAYGTPRRLTLVVEGLSDRQSDLEEEIKGPAKKIAVDAENNLTKPALGFIKSKGLSES
                     DIYFKQVGKEEYIFATIKQDGKETSEVLKDILPETIKSVVFPKAMRWGGKNLKFARPI
                     RWIVALLNDKVLEFDLEGIISSNVTKGHRFLGESTIEVDSIEDYFEKLEKNYIVLDQN
                     KRKEMIRKQCIEVANSLGGEVEFDEDLLEEVTYLVEYPTAFYGEFDVDYIKLPKEVVI
                     TPMKQHQRYFPVLKEGKLLPNFIAVRNGDSYRIDNVKAGNEKVLEARLADALFFYRED
                     TKRNLESYIEKLKTVVFQVKLGTIYDKTLRLEKLSADILDSLGLVDEKADTIRAAKLS
                     KADLVTGMVGEFDELQGFMGKEYAKVGGENDVVSEAIFEHYLPRFAGDILPKTNAGVA
                     LSIADKLDSIAGFFAIGIQPTGSQDPYALRRQALGILSILMDRKVAVDIKILIEHALD
                     NYSELDFNKEEVVEQIMNFFNERVKNLFKDLGIRYDVVDAVLSSDINDVSDMHMRALE
                     LNNWLEKDELVEMLTAFNRVSTLAQKAESDKIDESLLKEDAEIKLYNEFKQVKVKVNE
                     LLKDKKYGIALDEFASLRPVVDNLFDTVMVMDNDEAIKNNRLALLKQVYDTMLGICDL
                     SKIVYK"
     gene            complement(43802..44680)
                     /gene="glyQ"
                     /locus_tag="KR231_000939"
     CDS             complement(43802..44680)
                     /gene="glyQ"
                     /locus_tag="KR231_000939"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit alpha"
                     /protein_id="HBH0003344.1"
                     /translation="MNFQEMILALQKYWSKQGCIMMQPYDIEKGAGTMNPNTFLRSLG
                     PEPWQVCYVEPSRRPADGRYGENPNRLYQHHQFQVILKPSPDNIQELYLESLKEIGID
                     PSEHDIRFVEDNWEAATVGAWGLGWEVWLDGMEITQFTYFQQVGNIECELETGEITYG
                     LERLAMYIQEVDSVYDLKWNDKITYGEVFNKAEYENSMYAFELCDADMLFNLFDIYEK
                     EALRLMENGLVIPSYDYVLKCSHAFNTLDARGAIGVSQRASFIGRVRNMAKTVAETFV
                     KQREEMGFPLLKDGDK"
     gene            complement(44840..45439)
                     /locus_tag="KR231_000940"
     CDS             complement(44840..45439)
                     /locus_tag="KR231_000940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4342 domain-containing protein"
                     /protein_id="HBH0003345.1"
                     /translation="MSSNITIEMVDSVFERVPGATYAEAKEALVMCNGDVIEAVIYLE
                     NKKNTCNCKAKSAKETMEEVFGKDGENIKFQLKELLRKSSVVRIIVEKDGKTMMNIPL
                     TVGVVGLAFVPLATLVGLSAAVISKYRIKVQNEEDGEIVDLGELNEEKLHVLKNMITN
                     AAKDVKDVVVDKKEDDKDVTADLMKEESEKNKEDEDENK"
     gene            complement(45432..46205)
                     /gene="recO"
                     /locus_tag="KR231_000941"
     CDS             complement(45432..46205)
                     /gene="recO"
                     /locus_tag="KR231_000941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecO"
                     /protein_id="HBH0003346.1"
                     /translation="MIILNTQGIVLKAIRYKESDIILTLFTRKLGKVSAIAKGAKKNK
                     SSLLSSSQLFSYSNFTLKKQGNMYKVTQSEIIKSFYNISYDIEAFSYATYITKLVENS
                     ILENQTNNRLFILLAQTLYLYTQDNTDNRFITAAFELKFLDYIGFKPIVNKCINCECK
                     ILQNSVFNIYEGGILCSKCSKLFDNNIKLDLTTISLMEYVLRNDILTCSKAKVSKYIT
                     HELENILDKYLKVYVDNINFKSLHVLQSVKNNKGVDNDE"
     gene            complement(46171..46326)
                     /locus_tag="KR231_000942"
     CDS             complement(46171..46326)
                     /locus_tag="KR231_000942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqzL family protein"
                     /protein_id="HBH0003347.1"
                     /translation="MNNISWEVFKKTGSIDAYLYFCDCKNIHEEIEEVREKKEDDDNP
                     EHPGDST"
     gene            complement(46399..47778)
                     /gene="mgtE"
                     /locus_tag="KR231_000943"
     CDS             complement(46399..47778)
                     /gene="mgtE"
                     /locus_tag="KR231_000943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter"
                     /protein_id="HBH0003348.1"
                     /translation="MDRKLDASQDLLYEVKSLIDNNKVLELRELIEEYHIIDIFDIME
                     NLEEDMKIQLFEVLPLDMASSILEEGSVEFFISILSKLDVEHSKNILELMSLGDMADK
                     LSELEEEEREHIINLLNQENADYVKELLFYDEDSAGGTMTTGYISINKDMTALEAIDH
                     MREEAEEAETIYYIYVVDDEEKLVGVLSLRELIIARDANIVEDLMSENIISVYVDEDR
                     EEAVRLVSKYNLIAIPVVDRQEKLKGIITVDDIIDVMEEEATEDMYKFAGSSEHEREV
                     AEKENPTLREQIISALRGRLPWLIITLVGGLLASLILSNLDYIMNPVYAPLVFFIPVV
                     IGMGGNIGTQSSSVTVITLSNKDLNFSNVVREGIVGIITGLLCSIITGIVIYFVMRKL
                     DIVLIVSISLFINMVLGATIGAFMPVLLKKMDADPSTVSSPIISTALDITGIAVYFII
                     TTALLSKIV"
     gene            complement(47790..48683)
                     /gene="era"
                     /locus_tag="KR231_000944"
     CDS             complement(47790..48683)
                     /gene="era"
                     /locus_tag="KR231_000944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase Era"
                     /protein_id="HBH0003349.1"
                     /translation="MFKSGFVSIVGRPNVGKSTLMNNVVGEKIAIMSDKPQTTRNTIQ
                     AVYTDEEMQIVFLDTPGIHKPKNKLGEFMVKAATEAFKNVDLILFVVDDSKKIGPGDR
                     KIIEDLRSVKTPIILVVNKIDQLDQKDELFDIIKMYDREGIFKEIVPISALKGKNTDT
                     LIKVIQNYLEEGPKYFPDYMITDQPERVLIAELIREKVLHYLNDEIPHGVAVEIEKMK
                     ARNDKEIVDVSAVIYCERDSHKGIIIGKNGRKLKGIGKSARQDIELLLGSQINLQLWV
                     KVKENWRNLQNYINNFGYNDK"
     gene            complement(48747..49148)
                     /locus_tag="KR231_000945"
     CDS             complement(48747..49148)
                     /locus_tag="KR231_000945"
                     /EC_number="3.5.4.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine deaminase"
                     /protein_id="HBH0003350.1"
                     /translation="MDNIELLRLAEDARQHSYAPYSGFRVGAALLTKSGKVYTGCNIE
                     CASLGGTNCAERTAIFKAISEGDKDIYKIAIASDNSENNEQTYPCGICRQVIIEFGSD
                     IKIITGYTKGEVFEHSIKDLLPNYFSGNDLK"
     gene            complement(49267..49986)
                     /locus_tag="KR231_000946"
     CDS             complement(49267..49986)
                     /locus_tag="KR231_000946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase"
                     /protein_id="HBH0003351.1"
                     /translation="MKPEKTRQGIIKAFNAAIEGILYTFKFERNMKIHYLGSVAVLII
                     SLFFNFSKLEMIMLLMSICLVVVAEMFNTAIEKAVDLVTDEYHVLAKIAKDVAAGGVL
                     VAALNSVVVGYILFYDKLTDISGILIYKIRESELHITLICILLVLIAVVVVKALTSTG
                     TPLKGGMPSGHAALAFAIATAITLMTERVVASTLAYIMAVLVAQSRIEGKIHTFWETI
                     AGALLGVLIAILVFQLGMFYN"
     gene            complement(49992..50453)
                     /gene="ybeY"
                     /locus_tag="KR231_000947"
     CDS             complement(49992..50453)
                     /gene="ybeY"
                     /locus_tag="KR231_000947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416637.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA maturation RNase YbeY"
                     /protein_id="HBH0003352.1"
                     /translation="MDLILDDRQDKLEVSEELIEKIKDIIIECLDYEGYDDNYEVSLS
                     FVDNKEIHELNREYRGVDRVTDVLSFPLLSDDFEDVELEEESLGDIVVSLERALEQSI
                     EYNHSFEREVCFLICHSMFHLLGYDHDTDENTKEMREKEEHILNKLNITRE"
     gene            complement(50510..51625)
                     /locus_tag="KR231_000948"
     CDS             complement(50510..51625)
                     /locus_tag="KR231_000948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PhoH family protein"
                     /protein_id="HBH0003353.1"
                     /translation="MKIIVIKIVIIVKIIIAITTNKIKLKILGGLIQLIIQKKFTIAD
                     GNFERELFGNFDENVKLIEKTLNIDVILREGNIILIGEEKNVDSALKLMNELHQTVSN
                     GKHLDKQSISYSLSLLLEGSEQKIKELEGTIVITQRGKAVQPKTLGQKEYIKLIENND
                     ITFGVGPAGTGKTYLAVAMAVKAFKRDEVSRIILTRPAVEAGESLGFLPGDLKDKVDP
                     YLRPLYDALFEMLGADKFNKYLERGTIEVAPLAFMRGRTLDNSFIILDEAQNTTSEQM
                     KMFLTRLGFGSKAVVTGDVTQTDLPQNKKSGLIQATEILKGVPGIGSIMLTDRDVVRH
                     ELVQRIIRAYEKHDKREEFKKEERKKAKMQEKTFKRK"
     gene            complement(51564..52907)
                     /gene="yqfD"
                     /locus_tag="KR231_000949"
     CDS             complement(51564..52907)
                     /gene="yqfD"
                     /locus_tag="KR231_000949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sporulation protein YqfD"
                     /protein_id="HBH0003354.1"
                     /translation="MISFIRGYYVIVVEGVGLEQFLNHLIRNGISVYNVTRIKNTKME
                     FHIDRQDIKEFKNVYRGSKFDIKVKQKTGVPFIIKRVYKHKGMWICALVSLFLLMSTS
                     QFVTDVYIQSPEGIKKEALRNELYKVGVRPGVYKKSIDRKEVRDHMMSKFNDVAYLSI
                     NVKGTNIFVTVTKKAESLKSTDQSNYCNVIALKNGIIEKVIPRSGKSVIKSGDIVQKG
                     DVLLNGANTKSIPEVWASTFYESTKKASYVDTVNKKTGEKKNIYTLSFYDKEFTMRKN
                     IKYKDYVVENKEKKLSIGNYTFPIKIKTSTFYETKKVEVKRNKEELKKELSEKALKEL
                     EYIIPASARIIDVKHNFKVNKNMLEYLITVQTSENIAKIYPLSKSEAERFIKEESKPD
                     EGEEEVPSNPEKRPLNDIRNEFDEDNKDNKDQNNSDENNSNQNSNNSQNNNSNNN"
     gene            complement(52920..53156)
                     /locus_tag="KR231_000950"
     CDS             complement(52920..53156)
                     /locus_tag="KR231_000950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YabP/YqfC family sporulation protein"
                     /protein_id="HBH0003355.1"
                     /translation="MLEISTDLQVNQPVITVTSNTFISIENYLSILEYEVDLIRIKTK
                     VKTIKISGDKLSLKYITDSEIGIKGIIYNVEYVD"
     gene            complement(53369..53932)
                     /gene="raiA"
                     /locus_tag="KR231_000951"
     CDS             complement(53369..53932)
                     /gene="raiA"
                     /locus_tag="KR231_000951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome-associated translation inhibitor RaiA"
                     /protein_id="HBH0003356.1"
                     /translation="MQIIVSGRQMKLTDGIKGYVDGKLSRLEKYLDPESEVKVTVSAK
                     KDRQKVEVTIIPINGQIIRAEDVEDDLYAAIDIVCDKLSRQVVKYKTKVKDKVQNNKS
                     IRFENLDFIDNSSEFDDYDYDDEEDENIVIERRKKFNVKPMSSEEAILQMELVGHNFY
                     MFRNQDNFEINIVYKRKAGGYGLIEQD"
     gene            complement(54125..54622)
                     /locus_tag="KR231_000952"
     CDS             complement(54125..54622)
                     /locus_tag="KR231_000952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416623.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan-rich sensory protein"
                     /protein_id="HBH0003357.1"
                     /translation="MIISVKEIRNFLINIFIPLIIGYLSSILTMIISGTDISTYYLQL
                     TKPSFAPPAFIFPIVWTILYILMGISSYLILRKGYNLPKVRDAIFYYGLQLVLNFIWS
                     ILFFGFGLRFTALIDIIIMILVSIIMISKFSKIDKRSGYINLIYLMWLVYAGFLNYFI
                     WFINK"
     gene            complement(54733..55176)
                     /locus_tag="KR231_000953"
     CDS             complement(54733..55176)
                     /locus_tag="KR231_000953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GatB/YqeY domain-containing protein"
                     /protein_id="HBH0003358.1"
                     /translation="MSLKQKLQEDLKSSMKNKDTVRKSVVTLIRASIKQYEVDNRVEL
                     DEDGIIDVIAKQLKQRRDALVEFEKAGREDLIKETEGEIEVLKEYLPQQLSEEELEEI
                     VKSTISEVGATSMKDMGKIMSVIQPKVKGRADGKLINKLVKQNLQ"
     gene            complement(55206..55385)
                     /locus_tag="KR231_000954"
     CDS             complement(55206..55385)
                     /locus_tag="KR231_000954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S21"
                     /protein_id="HBH0003359.1"
                     /translation="MSEVRVRENETLDSALRRFKRQCAMSGIMSEVRKREHYDKPSVK
                     RKKKAEAARRKNAKK"
     gene            complement(55548..55898)
                     /locus_tag="KR231_000955"
     CDS             complement(55548..55898)
                     /locus_tag="KR231_000955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine triad nucleotide-binding protein"
                     /protein_id="HBH0003360.1"
                     /translation="MDCIFCKIANGEIPSTKVYEDDRVLAFNDLNPVAPYHILVVPKK
                     HYDSLIDIPDKEMDIVSHIHVVINKIAKEKGFDQTGFRVINNCGSDGGQEVKHLHYHI
                     LAGKKLPNYEAGQN"
     gene            complement(55941..57239)
                     /gene="mtaB"
                     /locus_tag="KR231_000956"
     CDS             complement(55941..57239)
                     /gene="mtaB"
                     /locus_tag="KR231_000956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (N(6)-L-threonylcarbamoyladenosine(37)-C(2))-
                     methylthiotransferase MtaB"
                     /protein_id="HBH0003361.1"
                     /translation="MKKVAFYTLGCKVNQYETEAMLELFEKDGYEQVNSEEYADVYVI
                     NTCTVTHMSDRKSRQYIRRVKKKNPDAIIAVVGCYSQVSPEEILDIEEVNLVMGTNDR
                     RKIVEEIKKINSSKKVSTVDDIMKVKAFEEIEISQTNGKTRAFMKIQDGCDRFCTYCI
                     IPYARGRVRSRDIDSIVDEVKKLANNGYKEVVLTGIHVASYGKDLKDRDIKLLDVIKQ
                     INQIEKIERIRLSSVEPILFTDEFVNEVLKMDKVCPHYHLSLQSGCDETLKRMNRRYT
                     TLEYKTIVDRLRSKMPDVAITTDVIVGFPGETNEEFKKTYEFLKEIELSQMHIFKYSP
                     RKGTPAATMENQVDPQMKHFRSEQLLNLSKVNFNKFATKFIGRELDVLFEQNIEGNKY
                     EGLTSNYIRVVVESDKNIQGQILKVKINDVKDEYVEGILL"
     gene            complement(57241..57999)
                     /locus_tag="KR231_000957"
     CDS             complement(57241..57999)
                     /locus_tag="KR231_000957"
                     /EC_number="2.1.1.193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (uracil(1498)-N(3))-methyltransferase"
                     /protein_id="HBH0003362.1"
                     /translation="MDRFFVEKNNINLQDKTCTIEGEDVKHISKVLRCKLGEKLEICD
                     KNNNEYICEIMNIDKSIVNLEILEKVDINRESELKVRLYQGLPKAPKMEMILQKLTEV
                     GVEEIILVQTKRSVVKVDDKKEDKKFERWERIIYEAAKQSKRGKIPKLRGVLSFKEAL
                     EDMKKNNVNICPYENERTVSIKHALKKCDSNIDSVGIFIGPEGGFSEEEIEQIQKNNC
                     NVVSLGPRILRTETASVVASTIALYELSDLGGEK"
     gene            complement(58018..58965)
                     /gene="prmA"
                     /locus_tag="KR231_000958"
     CDS             complement(58018..58965)
                     /gene="prmA"
                     /locus_tag="KR231_000958"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11 methyltransferase"
                     /protein_id="HBH0003363.1"
                     /translation="MNNWIEVTIKTTTEAVEPITNILYEQGAGGAVIEDPKDFLFQKK
                     NELDWDYVEEEVFKKNEEDDVLIKTYVSEEKNVMEFVEIIKQKVLGLKDFGIDIGEGS
                     VSLDQVNEADWANAWKAYYKPTKVGQRVVVKPTWEDYAMQEGDLIIELDPGMAFGTGT
                     HETTSMCIRELEKYVNKDSKVFDIGCGSGILAIAAAKLGAKEVVAVDLDEVAVKVAKE
                     NVLENKVEKSVSVMHGNLTDVIKDKADVIVANIIADIIKILAKDVQNFMKEDAIFISS
                     GIILDKVEEVKESLIENGFEIVEVQKLGEWSAIVSKLKK"
     gene            complement(59407..61815)
                     /locus_tag="KR231_000959"
     CDS             complement(59407..61815)
                     /locus_tag="KR231_000959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454738.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CRISPR-associated helicase/endonuclease Cas3"
                     /protein_id="HBH0003364.1"
                     /translation="MKNIMQKEILAKSYNLRTNQQEQTLVEHIKDLFEVLESILELNL
                     YSDKDVEILKICCALHDLGKINSIMQQKMEINNKISYSCSEEERKKLESDKKSLKKIA
                     RHNIFSGAFLKDILEKMNLSEEDKLYIYKSIMLHHGNYEDYMRLSISKVQEEIYEYIE
                     KGILEKEEFNLKDIESYINSILNVDFKFGEDVLDYDYIDKLSESMFIDSDYNNGQIDD
                     SVLNYRKFKYILYKGMLNLIDHSASSRQKGIKFYNDFTDEEIDNMILNEIYKSQGNLE
                     KNNIEFNTIQKRLRELSGRNVLTVAFTGSGKTAADYRKTFKRKFFLVPNKISAESFYR
                     KNIFQNKNDLDTRSSNDYIGLLHGDINLYSENEDNGEHDFVLTLRDIDLSINFCKPCV
                     IATVDQLLLSMFKFPGYEKIFAAVKNASITVDEVHLLEPKMFLILIYFMQFACKYLDV
                     DFHLMTATLPKSYKEQMINKGIIFQEESNENVTDKGEIVFIESNKEEEICEGKDVKVS
                     FIKEKEIKSIVEDALENKQKILIIKNTIDSVNRTYEFLKENLSDKYGGVDIDVLHSRF
                     KFKDKKEKYSKILNGEGDIWISTQSVEISLDLDFNIIISDLATMDSLIQRMGRCNRNN
                     KYEYGNFYILPSEDKIYDNKLKNTTKNILKDILKTNSIFTMGIRKTILDDYYDNSVVK
                     KYFEENFISCDKEIKNIYGINKEIFDGLDLIFNFEPYKNIVDSKKEAAKIFRDVDVSY
                     KIILEEDFYKEDRELQQDSIQVSGFIFNRLYYYGLISKVEGYMVLKSSSKFEYNSTVG
                     LILK"
     gene            complement(61842..62639)
                     /gene="cas5"
                     /locus_tag="KR231_000960"
     CDS             complement(61842..62639)
                     /gene="cas5"
                     /locus_tag="KR231_000960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CRISPR-associated protein Cas5"
                     /protein_id="HBH0003365.1"
                     /translation="MKVLQCKLKQPTAHYRDPKVFQNEYISTLNLPSKTTIMGMITYL
                     CDRRLNSDIDIGIIGTHHHRELEFSRGENIDFWNEYTNMRKGKDKEKFLLQGNYYDYY
                     KEHKAQNSILNYEVLKEVELTIFISCKDDEELEFIRKKLESPCKYANLGRKEDFVIPS
                     EKGCFVKEVELKEVIPMNTRDAIKENIKLKNTYVRVDLRDKENVETIINQGVLIALPY
                     KYKDLEANRDDRVYEFCHYIYVDNDGIYPKNIKVNVCIDTKEVFTWL"
     gene            complement(62655..63671)
                     /gene="cas7i"
                     /locus_tag="KR231_000961"
     CDS             complement(62655..63671)
                     /gene="cas7i"
                     /locus_tag="KR231_000961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I-B CRISPR-associated protein
                     Cas7/Cst2/DevR"
                     /protein_id="HBH0003366.1"
                     /translation="MNEKRVKGVTLTILTESPVPLSYDQGYGNYTPIKKEQYRDKVHA
                     KTSIATITYDLRRILHQEYGWNLSNIVFGKKGNIYPSIKKNVGCVDENGLETDVFGYL
                     IPLKEKGSISKASPLRIIPFRSLNSYRGSTQLITNRGFLSSEFGRKYYDEREENEVLR
                     DENFPTTQALAIEETLSDYYVYTITLELDRIGVVEVEEDGKLLLPEERKFMSKELREK
                     AVKDILDAITVFTRNIKHSSVLLKPLAVMGGAFDKVVPFFWDDVDYNADSGEINLEGV
                     IETIESYSLKESNTILAINDRLKISNKKELNKFNLSKYPVKEIKNLADRLEIGEDNMW
                     YLKE"
     gene            complement(63691..65166)
                     /locus_tag="KR231_000962"
     CDS             complement(63691..65166)
                     /locus_tag="KR231_000962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0003367.1"
                     /translation="MREIKAKFYRSGDIVRDIGIVYFCELLMDLKNELEKNDYKLKFT
                     CELNRNYLSLESAEYIDPKYISDYILENQLFKVFKNGKKETLEKIFSNIDNLTYVNFI
                     EELDKSSATEKQKEGIKKDFKNRRFPYVRNSGKYGLNTSLENMEKNVKRIVDIVIKSN
                     IEIDEIDKLDLKQYEEKDSVCNVCNINKTTKLDIDLRERKDSKYNFLFRGAEKSGFKR
                     SGQVESNICFECEFFNLMCLLYINLKRPMVFAYTNDLRELAFLNHKIMLKRKMYSDKS
                     FYKKLLHEKISSIRLYRIDIDTNKGIILKFDSIIEYKELLKKIELIDIIDNYNFSREP
                     MNTRNLGKKMINNGNLSNLKELLLDNISVLRQLTGTSREMDFVSSSYNIGLYIKLCWI
                     VDGREEYKMKNYIESNLIYSRVGKDLFNKMTDESRRKNFSMKVIQLLKSNDRTQLFQT
                     IMHVLVSNGILIGEGFVEGLMQSSELELNTNVGLFIQEIMK"
     gene            complement(65171..>65677)
                     /gene="cas6"
                     /locus_tag="KR231_000963"
     CDS             complement(65171..>65677)
                     /gene="cas6"
                     /locus_tag="KR231_000963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CRISPR-associated endoribonuclease Cas6"
                     /protein_id="HBH0003368.1"
                     /translation="GDIIFNISFYNYSMFSKLYNGILKVKELEYKGYRFKIKNIKIHK
                     EHEIKENGVIFKTMSPIIVKNKEGKYLDVEDSNYIECLNYIANLTLESIRGSGLRKPL
                     EFIPLNFKKRVLKEKIRGFKEREFYYINAYAGTFFLKGNMEDLNALYKMGIGYRRTEN
                     AGMVDILK"
BASE COUNT        21292 a        11679 c         7323 g        25383 t
ORIGIN      
        1 gcattaaatc ttctagtaca tctttcatat cgaagtacac atcttctaat aaataaaaat
       61 agccttcctc tatatctttc aatttatcta tagtatccat ttttttactt atatctttca
      121 taatttctaa attttgtata tttacatcta tgattgttaa taagtacatt ctcacagttt
      181 ttattatttc aacagaaaaa tctacaatat tataatttcc ttctttttta tataatgact
      241 ccttaaattt gttaaaacaa ttatctaaat tagaatttat atcgttaaat ggtggtctta
      301 ttatgtcacg tattattaaa agattttgta tatctacatt atttgtgatt gcctcatcca
      361 aaataaataa attatatgca tcatttaatg ggtcatgggc atctccacta aactctaagt
      421 taacaaattc aagtaaattt ttcaatgata tatagttcat acatctcata ccacaattta
      481 tatatttttc ttttatatct acaaataaat ctctaatgtt atttacaaac cttggatggt
      541 tatttttttt agcacttctc atatctgtgt tattgaaaca tgtcaaatcc aaattaccaa
      601 aagtatatat tcctttaata tcagaaaata tgccaagcca ttttttaaac tttctcatga
      661 cctcttcata acttggtgca ctcttcaatt cttcagaaga tatatgtgtt aattcttgta
      721 tatgaggata caactcctca ttacttactg gtcttattaa agatttaaat ttatcaatat
      781 tttttgtttt ttcatcatac ataactgctc cgattgcaat tatatcagaa ttaaatactg
      841 ctctttttga tttagaattt ggcatattca tttcaaaatc tatatatact cttttcaata
      901 taaacaccct ttccaattgt ttatagtgat tctttttaac tatttttatt caaaattttc
      961 taagaaagaa tgtttctccc catctttttg ccaaccaagt actgaatcaa gatttacatt
     1021 ttctgccgcc ttaaatatag atttttctac atttttaaaa tttgattcta agctctttat
     1081 taagtctttt atctcatatc ttttattacc tgttttttta gcagcaacca tacatgcaca
     1141 atttaatggc catataccac tattttgaat aaatcttata atatgttctt ctcttatata
     1201 ataaagtggt cttataattt ttataccttc aaaattagta gaattaagtt taggaagcat
     1261 tgttttaaaa tttccagcac acaataaatt aagcattgtt gtctctatta catcgtcata
     1321 atgatgacct aatgcaagtt tgttacaccc taattcttct gcctttgaat ataatgctcc
     1381 tctcctcatt cttgcacaca tatagcatgg ataatctttt gctatttcat ctgctatctc
     1441 aaatatcctt gaatcaaata aatgtattgg tatatttaga tactcacaat tatctataag
     1501 taattgtctt atatttgcat gatatccagg gtccatagca ataaattcaa catcaaaatt
     1561 aacttgtcca tgttttttta actcttgaaa cattttagcc ataagaatac tgtcttttcc
     1621 accagaaatc gctacagcta tcttatcacc ttcttcaacc aatttataat ctcttattgc
     1681 cttcataaac ttagaccata aatttttcct atattttttt attatacttt tttctatatc
     1741 tcttactgga agtctttcct caaaaggaac tataatttca cagccttttc ctgatagttc
     1801 actcatctaa tcacctcgta tatttatgtt aataatattt tacaaaaaag tctaccttca
     1861 tccacaaaat actataattt ttactttaat tttactaaat aatttatagt ttacaataac
     1921 acataaactt ataataacat aaataacctc tttcttttat tatctttttt atttttctca
     1981 tttaatattt tattattagt aacgattttt aaatgattga atattataca ctagatagag
     2041 ttacctatct atttacaaca aggaggtttt catcttggaa aataagacta gagatatcaa
     2101 aaaaaattgt ggtccatctt tggctagacc atacattaat aatcaaattt tcacagaaat
     2161 gtactgcctt tctgatgcat taaaatttgg aactatattt ccagaactaa acttactaga
     2221 gtctgaaatg tacaacaaag aattatatgc taagccaaaa aaatatagag gaggtagaag
     2281 ataatgaaag actcatctag agctgaactt atgagaaaag ttcaggaaac atcttttgca
     2341 tgtgttgata tgaacttata tttagacaat caccctgatg ataaaaatgc tatcaacact
     2401 tataattcat tatgtaatca atttgcgcaa gctagatatg cttacgaaaa taaatacggt
     2461 cctttaacta actttgggta tgctccaagt agatgccctt ggcaatgggc tgaccaacct
     2521 tggccttggg acagagaatt taattattag acatcaagta ttggaggatt gaaaattcat
     2581 gtggatatat cagaaaacta tacaacaccc agttaatata aaaacttgtg accctagaat
     2641 ggctaaattt cttataactc aatttggtgg gccaaatgga gaacttgctg catctttaag
     2701 atatttaagc caaagatata caatgcctac tggtaatatg cgtgcacttt taacagatat
     2761 tggtacagaa gaactagctc acgttgagct tatatgtact atggtttatc agttaacttc
     2821 tgatgcaagc ccagaagagt taaaagctgc aggtcttggt tcaaactatg ctcaaaatgg
     2881 atatggaatt tatccaacag attcaaatgg tgttccattt gatgtaagac ctatagcagt
     2941 tatgtcaaat cccgtaaccg atttacatga ggatatggca gctgaacaaa aagcacttgc
     3001 aacttattat caacttataa acctaacaga tgacgttgat gttatagatg tattaaaatt
     3061 cttgggtcaa agagaaataa ttcattatca aagatttggt gaagccttaa tggatgctta
     3121 cgagttagaa gaatctcaaa aaatgttcta aaatttttat ttgtataact attattattt
     3181 gataatttat aatttactgt tgtgttaaaa tttataaaaa atataaatat aatttatttt
     3241 ctataaacag agaaaataaa taaaaagcag gtatcaatca aatagtaaca tgtattatac
     3301 tatacattac tatcaatatt gtacctgctt tcatattata agcaataaag aaaaatctat
     3361 ttattaggtt ttataataaa aacaattata aaactcttct tgcatttaca tatctacttg
     3421 aatagtagct actatttata ttagatattg ttactttttt tgatgaacct gaagatgcat
     3481 gtatcatatc tccatttcct atgtatattc caacatgact tacagaacca ttatttgaac
     3541 cttgtgtatc aaagaatact aaatctccac ttctaaggtc tcctctattt acatatgttc
     3601 catacttact ttggtctcta gatactcttg gtatactaac tcctacagat tttttcataa
     3661 cgtactgcgt gaatccagaa cagtcaaaac tatttggacc ttctgctccc catacatatg
     3721 gttttccaag tagtgtcttt gcaaaactta ttacactatc agctccttga cttggagaat
     3781 tagtcgaata agatggaatt gaagtatcaa cagaaccttt ttcagcaagg tattgacttg
     3841 acacatatcc agtttgattg ccataactta tttttgtcca tcctccactt tcagaaatac
     3901 ttccaacctc agtaccataa cttaatgtag ctattttaga atgacttgta cctggtcctg
     3961 ttctaacgtt caatgacttt gctgttacaa cctttgtacc ctttacaagg tcatttgaac
     4021 tgttttcagc attttcattt gtagagtcat ttacactagt tcctaaatat ttacttgaaa
     4081 cataacctac tctaccatta gaacttattt ttgaccatcc atttgactca gatatgtatc
     4141 cgacttcagt cccatatcct agtgttgata ttttagaact acttgtactt ggtcctgttc
     4201 taaaatttaa tccttttgct gttacaactt ttgtcgactt aactgaagta tcactacttt
     4261 cattgctact tccaaggcta tttattgcta cataatttcc atgcacataa cctgtgtttc
     4321 cattatattt aacttttacc caagaacctt cttttcctac gtactcaact ttatcacctt
     4381 tgtaaagttt ccccattgat tcatggtttg tacctggtcc ttttctaaaa tttaccgcat
     4441 tccctgttat tgttctgctt tctatactca cactctctac ttcagactca ttagcatatg
     4501 ctaaattccc catagtaggc attattatcg cagttgccat tatactggct gctattctct
     4561 tttgattaaa attcataact ttccactcat ctcctctttt ctactatctt tatttcactt
     4621 caaaatataa aagaaataat tgacactatc aaaatatcaa ttatttcttt tatattaata
     4681 ttattacaaa tttgtaacta tttgtctata gtaatatttg cttaccataa attaccatgt
     4741 ataaatttta atctttaata gcctgtaatt tagtaatata gccatctttt acctttttta
     4801 aaaatggcta tattttttaa cttttttgta actttttaaa atccagttga gccaaaccca
     4861 ccttttcctc tttcggagtc acttaattct tttacttctt ctatgttaat atcatagata
     4921 ggttttacta tcatttgagc aattttcata tgcttttcaa ccttaaaatc atttttacca
     4981 tgatttatta atataatttt aagctctcct ctgtatcctt cgtcaatagt tcctggtgta
     5041 tttaatacag taacagaatg ctttaaggca agcccacttc taggtcttac ctgcgcttct
     5101 gtcatagtag gaagctctat acatatccca gttttgataa gtttagtctc tccaggaggt
     5161 attacaacct cttctataga atacaaatcc ataccagcat cacctttgtg agcaaaatta
     5221 ggtattatag catcatcatt taattttttt acttttaaat tgtacatctt atatctcctt
     5281 tcaactttct ataaatatta taacttaaat ttcgacctct tgaagttttt tatttttttg
     5341 tggtaatata attattagtg ttttaaagga ggatttttta tgaaacttgt acttgctgag
     5401 aaaccatctg tggcaaaaac tatagcatca tttttaggtg caaagaccag acaagatggt
     5461 tactttgaag gaaatgatta tataattact tatgcagttg gacacttagt atcattatat
     5521 gatatgaagg attatgataa agataaatac tctggctctt ggaaaatgaa caatttccca
     5581 tttgttcctg aggataagtt taaatttaag attgatagtt ctaaaactaa acaattcaac
     5641 actgtaaaaa agcttttgaa tagaaaagat gtagaatatg taataaatgc cactgataat
     5701 gaccgagaag gagaacttat agcattttta atatttttac tggcaaaaaa taaaaaacca
     5761 gtaaaaagaa tcttggtaaa tgaatggaca ccagaagata ttacaagagg tataaaaaac
     5821 ctaaaagatg aagatgaaat gagaaatctt caagctgctg gatatactag gcttattact
     5881 gactggttga ttggaataaa tttcacttct gttgctacat tgaaatacgg aaatgggaaa
     5941 ctattaaaca taggtagggt aattcttcca acagttaaat tagtctatga tagagatatg
     6001 gaaatactaa actttgttcc taaaacttat tatgaaatag aagggcattt taaagctgaa
     6061 gctggtgaat ataaaggtaa atatgttaag ggtaaagaaa gtaaatttga tacacttgaa
     6121 gatgcaaata aaattatagc ttcaattaca tctgaaactg gtaaaatact agataaaaaa
     6181 gttactatgt caaaggaata tgcaccaaaa ctttttagtt tgacatcact tcaaggatat
     6241 ataacttcta agtattccaa ttttacatct gataaggttt taaatgtctg tcaatctctc
     6301 tatgagggta atggtaaggg tggatacata acttacccta gaactgattc cattttctta
     6361 gaagaaagtt tggcttcaaa agcttctcaa actttagata aattaaaggt tggtcttgaa
     6421 tatgaaaata aaattaaatt ttctaaaact aaaagagttt ttgattcttc taaagtagac
     6481 tcccatagtg ctataattcc aacttatata attccaaaaa gtttatctaa ggatgaacaa
     6541 ttagtttatg atgccataaa agatagattt gtagcaaact ttatgcctcc tgctgaatat
     6601 gagaatacag aaattaagac tgaagtagat aattgtactt tcttaacaaa aggtaaggtg
     6661 cttaaatcaa aaggatacct tgaggtatat aataaggaag aaaaaaacga tttacttcca
     6721 cttgtaaata aagatgatgt tgtagatgtg ttagaaataa aaccattaac taagcaaact
     6781 actccaccta aaccgtatac tgaggacaca cttttaaagg ctatgaaaaa ttgtggtaaa
     6841 aatgtgcctg aagaagatac aacagtgcta tctggatatt cgattggaac atcagccaca
     6901 cgtgctgatg tgttaaagaa gataagtcaa gtgggctatg taaagaaaaa aggtaaatct
     6961 tattctataa cagaccttgg gaaaaattta gttgaaattt ttcctgttaa agacttattt
     7021 gatgtagatt atactggaaa acttgaaaaa agtttaagcg atattcaaaa aggaaagtat
     7081 acaagaaaag aatatcttac taatatcatt agttttatat atcaaaatgt caatattata
     7141 aaacaagatg cttcaaaaaa tataaacaca gaagcatata ctttcgattc aaaaactaaa
     7201 aaatttacta aaacaaaaga aaaaaaacag aaaaaagatg taactaatac tgaaaaagaa
     7261 gttgctatat caaaggattc taataacaaa aaagaagtta aaaatggtga tgaaaatcaa
     7321 tctcttggca aatgccccat ttgtcaaggt gatgtactag aatttgacaa aggctttgct
     7381 tgtaaaaatc ataaagaatg taaatttgtt atttggaaaa atgataagta tttaagtctt
     7441 tataaaaaga aagttaacaa aacaatggtc aaaaatattt taaaaaaagg tgaaactaaa
     7501 gtaaaatctt taactgctaa aaacggtaat aaatttgatg ctacattaaa atatgataaa
     7561 aatccagata ctggctattt caattggaaa atagagtttg acaactaaat attcataaga
     7621 aaagaaatag cagtagtata ataatctata ttatattact gctatttctt ttcttatgaa
     7681 gtttcaactt ttttaatagt gacttttaca atcacactct aacctaattt ctttactatt
     7741 tctgataact ttaatgtatg ttcatctaat aaagttagtt cctcttcaga aagattagat
     7801 aattttttta ctagagattc tttgagaata gcttttactg catcaaataa tttaaatgct
     7861 ttatctgtta attcaaccct aagaatcctt ctatcttttg ggtcaggaaa tttattgact
     7921 aaaccatgtt ccactaatct gtcaataatc ggagtcatat ttgattttaa aattcctaaa
     7981 ttagaagcta tttgagaaat tgatgatgaa tttgatgtca taagataaag aattacctta
     8041 gcatgtgatg gagccattgg acattcttca aaataagctt tcattatatc agagttattt
     8101 tgaaactttt ttaacaaatc gctttcttta aatatattat tttcaagcac aaataaaaaa
     8161 tctaaaaaag agtccgctat tttaagtata ttgttgttat ccatatttgt aacatccctt
     8221 caatagataa tataataaaa cattgttgtt taatatagta taaattataa actattaata
     8281 aatttaaaac aagaaaaagt tattgactca taataattat aaatttataa tcaaattaga
     8341 gaattataaa ttgccaataa agggaagttt tttaattagt ctaaaactaa acttaaatta
     8401 taagacactt taaattctac aacaagctag tgtgcaatat ataataggag gagatatgaa
     8461 aagatattta atagttttct taatgtgtag ttcactgttt ttagttggat gtggaaaaac
     8521 agaagaatct gaacctgaga aaccaatagc agtttctgtt caaaaagcaa taggtggaga
     8581 aattgaaaac acaaattctt tctcaggaac tacaaaggtt aaagatgaaa cagctgttac
     8641 tgcacagact gttggcacag ttcaagaagt gtatgtaaaa cttgggcaaa atgtaagaaa
     8701 aggagatgaa ttattgagta taagcagtcc agagctagaa aatagtgtaa agcaaagtaa
     8761 agcctcacta gatttagcaa aagcaagtta ttcaagtgcc actggtggtt cattagaggc
     8821 acaagtaaat caggcaaaaa cagctcttga caatgcaaag attcaatatg aggagtctca
     8881 aagaaattat gacaataata agattcttta tgaacaggaa gtcattagtt tagaccaatt
     8941 taaaaaaata gaattttctt tagagcaaac aaaacaacag ttagattctg ctcaaagagc
     9001 atacgataca gcaacttcaa aaagtatacc tcaagctaaa gcacttgcta aaaaacagct
     9061 tgaccaagct caagtatcat ataatttagc aatgagtaat ttagacaaat taacattaac
     9121 atctccagta gatggtacaa taacagctaa aaactttgat tcaaaggaaa tgataacaca
     9181 atcacaacca gcttttatta tttctaatcc taatatacta gaagttgatt taaatgtagc
     9241 agaatcagat ataggtaaat ttaagaaaga tggaaatgta gatgttataa ttgaagacca
     9301 aaggatttta ggaaaaatag attatgtacc ttcagtagtt gaccctcaga catctttata
     9361 tcctgttaaa gtacttgtaa ataatacaaa caacaaattt aaggcaggta tgtctgctca
     9421 agtaaactta agtgttgaaa aagaaaatgg tgctgttaca gtacctaaaa aagcaatatt
     9481 tgaagaaaat ggtaaaaaat atgtatacat agcaacaaaa gacaatatag caaagaaaca
     9541 cttggttcaa actggaattg taacagagga taaaatagaa attaaaagtg gtgtaagtga
     9601 taaagataca gtgattatcg gagggataag tcttatttct gacggaacta agatatttcc
     9661 tgtagaaaag gagaagtaga ctatgaattt aacacagact tccgttaaac gtcctctcac
     9721 aatcataatg gtctttttag tattaatagt ttttggtggt attggatata aaaaaatgtc
     9781 aataaatcta atgcctgata tagaaatacc agttgtaatg gtcatgacta cttggacagg
     9841 tgctggtcct caagacgttg atgaacaagt tagtcaaaaa gttgatgaaa gtttatctgc
     9901 cgtttcaaat gtaaaatcta ctatatcaag ttcacaagaa agtgtttcta tggtagttgc
     9961 tcagtttgaa tttggaacta atttggatga aataatgaat gatgttaggt ctaaagttga
    10021 tgcattacag accagcctcc cagatgatgc agctaaacca acagttttaa agctggatat
    10081 gaatgcacag gctataggtc aacttgtcat atctggagga aatgaaaata gttcacaagc
    10141 cttaagaaaa tacgctgaag atgtaattca gcctaaaata gaatccatag atggtgttac
    10201 ttcagcagac cttaaaggtg gagaaaaagc acaggttaat gtaatagctg acccagctgt
    10261 tctttcaaat tatggagtta gtttatccac tataaaaggt gtcttatcct ctagtaataa
    10321 aacattccct tatggttcaa ttactcaagg tgaggataaa atagttttaa gagcgattga
    10381 taaattagaa tccctagatg atataaaaca gattcaaatt cctgtaaaag gaggaaatac
    10441 agttagatta gataatcttt gtagtgtaga ttatggatat gcagacaaag atagtattta
    10501 tagatacaat ggaaaagaca gtttggtaat agatatttct aaacaacaag atgccaacac
    10561 tgtaaaagtt atgcagagtg catacaaata cgtagatgaa ttgaataagg aaaatcctca
    10621 atttaaaatt aaaattgcta atgatacaag ttcatacata agtgaatcaa taaacagtgt
    10681 aatgagcaac ttgcttataa gtgctgttat cgcatttatt gtaatatttg ctttcctaaa
    10741 aagtgtaaga gcttcactag ttgttgcagt tgcaatacca atttctataa taggtgctat
    10801 agcaattctc tactttactg gtgaaagttt aaatcttatt actgcaagtt cattggtaat
    10861 ttcagttggt atggttgttg ataatgctac agttgtaatt gaaaatatat ttaaatatag
    10921 gaaaagtggt agattgagtc ttgatgattg tgctattgag ggaacaagaa ctgtaacaaa
    10981 tgcaatactt gcatcaacat tgaccacaat agcaatattc ttacctatca tgtttacaga
    11041 aggtatagct aaaataactt ttggggcatt aggtaaaaca ctaatagctt cactagcatt
    11101 ctcctttata ggtgcaatta cactcgttcc tagtgtattt gcaaaattaa gcagagaaaa
    11161 aaatagtcaa aagatgcaag aaaaagatag tcctatattt gataaggtaa gtgaagcata
    11221 taaaaaatta ttaagtgtat gtttgagaca tcaacgctta gttgtaatat caagtttact
    11281 tatttttgta gcttccttat ttggaatggg atttataggt atggacttta tgcctgcagc
    11341 agacaagggt gaattatcta tttctataga acttccaaaa ggtcttagcc tagaatccaa
    11401 tgattactat gtatctatga ctgagaaaaa agtctcagat attccagaaa ttaaaacttt
    11461 aataacaact ttgacatcag attcaaataa tagtaaagca agtatagcaa ttgaattaga
    11521 atctcaaaaa aatagaaaaa gaactactga tgaaatagaa aaagagataa ttgatagagt
    11581 ggctactgta ccagattgta aaataaatgt aagtcaaaac agtagtgtta tgggtggagc
    11641 tggaggagca gacttcacat tagaaatgaa aggtcctgat ttagatgtat taaaaatact
    11701 gggaaaagaa gctgaaaaag aatttagctc tataaaagga tttagaaatg ttgaaacttc
    11761 tcttacagat acaacacaag aagctcaatt tactatagat aaacataagg ctcaagaata
    11821 tggtgtaaat accgctgaaa ttgcaggcat gttacgtaca gcaataaatg gtgactccgt
    11881 aaccactgct actattgatg attacaaagt ggatgtaaac ctaaaattta aagcagatac
    11941 tattgatagc ttagaagata taaagcaact aaaagtaaac tctgcaactg gaaaagaagt
    12001 tcctcttggt gccttttcag atataaaaat ggcagatggt ctacaatcta tatctaggac
    12061 tgatggagat ttttctgtaa atataactgc tacacttgac aatttagatg ctggtactgc
    12121 tacaaaacta gcactagaaa aaacgaataa aatggtaatt cctaaagatt actctatagg
    12181 tgttggtggt gaaacagaaa tgatgaatga atctatggca agtcttggat tttcaatggt
    12241 catagctata gcattagttt atatggtaat ggtagctcag tttgaatcat ttagtaaacc
    12301 atttataatc atgttctgtg ttccatttgc attcgttgga gttgtgcttt cgcttctagt
    12361 tagtggtcaa agtttaagta ctgtcggtat gctaggtata atcttactta tcggtattgt
    12421 tgttaataat ggtatagttc ttattgacta catagagcaa cttagaaaaa caaatcgtaa
    12481 caatgattta attggtttgg tttcaattgg ttgtgcagca agattaagac cagtcttaat
    12541 gactacagca acaacaattt taggtatgtt gccaacagca ctatctcttg gtgaaggtgg
    12601 agaaactatg caaccactag ccatagttat aatgggtggt ctaactgtat ctacacttat
    12661 aactttggtg cttataccta ctatatactt aatatttgat aaatgggaaa ataagttttc
    12721 agacaaaatg cctaaaatat ttggtaagat aacagataaa ataggaagta taaaacgtaa
    12781 aataataaag aaaccaaaat tgaaagctaa agtttaaata gaatggaggg tgattgtatt
    12841 gaataaaaaa atgagcaaaa tagttgcaat tagctgtggt gttggtataa taactgccaa
    12901 tttaatccca gtttacgcag ataataatac ttcttctata aacaaagttg ataattctat
    12961 tttaagtgac tcaaataaaa gaacatctga aaaggaaatt ttgactgcta gagaagctgt
    13021 tagtgctgca cttaaaaata gtgaaaaatt aaaaatgaaa tcagaagaaa taaaaatgtt
    13081 aaaagaaaag ttagaagtac aagatgagtt tgatagtttt actggaagtg acaactcgtt
    13141 tccatacgac caaattggac ttcttaaaaa tcaaagtgaa caggctaaag gctttatgga
    13201 ggaccaaata gcaaatgata ttactaataa atttaacgat ttagtttcaa gagaaaatga
    13261 gctagataaa ataaaaaaca atcttgaaat aaaaactaaa gaaattaaag atatgaaatt
    13321 aaaaaaagat ttagggttag taacatcttt agaaactgaa tcagctgaac ttgaacttca
    13381 aacactacaa aatactcaaa aagctaaact tcaagaacta aaaaacaatc aagactattt
    13441 taagttatta actaatatag atttaaataa ttatcaattg gataaagaat atagatttga
    13501 atcttttaga gtaggtggct cagttgattc atatatggaa ggtaaggtta atgaatattt
    13561 aaaatacgac caattgattt tagaacgtac agaagaaagc tttaatgata aagatgagaa
    13621 caaagcagat ttaccagata gacctaacct tacaagacca gttgctccta caaaaccaga
    13681 gcaaggtaac ctaactgatg atgaatacaa ggttcttatg gataagtatg aaaaagatta
    13741 tgatagatat aaaaaagaag ttgaagcata caatcttgaa agacagactt atgctgctgg
    13801 ccttactact tatgcaaatt atcttcaaca aaaatttaat actgaaaatg gtctagtaac
    13861 attagaagac agtaaaaaag ctcttaaaaa agggttaatt gatagctatg ctcaattact
    13921 tgctttagaa gatacaattc agattactaa aaaacaactt gatttatcag aaaaacaatt
    13981 aaaaaatact aaattaagat atgatttagg attaattact ctaactgatt ataaaaaaca
    14041 agtggtaagt aatgaagatg ctaaaaatag ctatgacact cttattgtga attataactc
    14101 actaaaaaat ggtatagaaa aaccttggat acttaatact ggaaaataat tctggtaaat
    14161 agaaagatta ctttaacata cgtttgatta aaaaatagtt atgcatactc gtggctttag
    14221 tcatggaaga ttcagaaggc aaataataga aatagattag taaaaatata tttacttata
    14281 aaactgtata cttttataga ggctatctca aaatagagat aagcctcttt tttattgttt
    14341 aaattataaa aatatatttg attccataca aaaagagtgc cttctgaact aaaaagttca
    14401 ttttgagaca ccctcaaaag cttaactcta aatttaatta ttttttatca aatgtttcat
    14461 ctattttaca tctcaccatg ttaacaaatt cagaaatatt atatcctcta agtttgcatc
    14521 cacatttagg acaataatcc agtttcctag ataccaaagc cctacaacta ggttctggac
    14581 atcttatttt tagactctca tctgctactt taaatccaca tcgtgggcat atactacctg
    14641 gacgtgatga tacttccttt ccacatttag gacactttgt caactttatc ccctccagta
    14701 aactcaattt aattgatagt tgaaatttct ctctacaata atatatgcaa tataattaaa
    14761 tacgtttcac ttacaactat ataagttaaa tttttataat aaaaatcccc tatattcaat
    14821 ttacaaatac ttaatttgat acattgaaca ataggggatt ttatttttat ttagttacat
    14881 attttgcagt ctattattat ctaggatttt ttatagatgc ttgagctgct gcaagtctag
    14941 caattggcac tctaaatggt gaacaagata catagttaag tcctacacta taacagaact
    15001 ctactgaaga tggttctcct ccatgctctc cacatattcc tagttttaat tctggtttaa
    15061 cttctctacc taatttagct cccatcttaa ctaacttacc aacaccattt tggtctagta
    15121 cttggaatgg gtctttttct aatatttctt catctacata ttgacctaag aatttaccag
    15181 catcatctct tgaatatcca aatgccattt gagttaagtc attagtacca aaactgaaga
    15241 agtctgcttc ttgtgctatt tcatcagcag ttaaacaagc tctaggtatt tctatcatag
    15301 tacctacagt ataaggaact tctatacctt cttcttttat tatagcgtca acagtttcta
    15361 ctatcatttt tcttattatt tttaactcat ttacttctcc aactaatgga accattatct
    15421 ctggagaaac tttaacacct gctttgattg cttctatagc accttgtatt atagctttag
    15481 attgcattac acatatttca ggataagtta ttgcaagtct acaacctctg tgtccaagca
    15541 ttgggttaaa ctcatctaaa tcaactattc tcttcttaat atcacttact tttattccca
    15601 tagattttga aagttcttct atagtctcat catcatgagg caaaaattca tgtagtggtg
    15661 ggtctagtaa tcttatatta actggttttc catccataac tttaaataac tctacaaaat
    15721 cctctctttg cattggtaat attttttcaa gagctttttc tctttgttct actgtattag
    15781 ataatatcat ttctctaact gctggcaatc tagcttcatc aaagaacata tgctcagttc
    15841 tacatagacc tataccttct gcaccaaact ctatagctgc acgagcatct ctaggattat
    15901 ctgcattagt tctaaccatc atacatttgt gtttgtctac ccagttcatt aatttttcaa
    15961 aatttccagt taaagatact tctgttttct taacatctcc taggtacaca tttcctgtag
    16021 aaccatctat agaaatgtat tctccttctt ttataactac atcatcaagt gctcttattt
    16081 ctttattaaa ctcatcaact tttatttctc cacatccagc aacacaacat ttacccatac
    16141 ctctagcaac aactgctgca tgtgacgtca ttccacctct agctgtaagg attccttctg
    16201 ctttaaccat tccttctata tcttctggag atgtctctag tctaactaaa actacttttt
    16261 ctcctttttc atttgctttt actacatcat cagcattgaa ataaacttta ccacttgctg
    16321 cacctggtga tgctggtaaa ccttttgcta taaccttggc ttcttttaat gccttatctt
    16381 caaattttgg atgtaataat tggtctaatt gattaggctc aattctcatg atagcctctt
    16441 tttcatcaat tattccagct tcaactaaat caaccgctac atttattgct gctgctgctg
    16501 ttctcttacc atttctagtt tgtagtatat ataatctttc attttctata gtaaactcta
    16561 tatcttgcat atctttataa tgaccttcaa gtatatgagt aatttttaca aattcatcga
    16621 atacagctgg cattacatct gcaagagttg atatattttg aggagttctt atacctgcaa
    16681 caacgtcttc accttgtgca ttcattaaaa attcaccaaa taatttattt tctcctgtag
    16741 ctggatttct agtaaatgca acacctgtac cactagtttc tcccatatta ccaaatacca
    16801 ttgattgaat atttactgct gttcctaagt tatgagctat atcattcaat ttacggtata
    16861 cgattgcacg aggattattc catgatctaa atacagcctc tattgcaagc attaattgct
    16921 cttttgggtc ttgtgggaaa tcatttttta tttctttttt ataaattgct ttaaattctt
    16981 ttactatttc ttttaaatca tcagttgtaa gttctgtatc aactgtgtat ccctttgctt
    17041 cttttactct gtctaataca ttttcaaatt tatattttgg aacttccata gcaacatcag
    17101 aaaacatttg tatgaatctt ctgtaactat catatgcaaa tctttcattt tgtgtagcct
    17161 ctgctaagcc aacaacacta ttgtcattaa gacctaggtt aagaattgta tccatcattc
    17221 ctggcataga gaatactgca ccagaacgaa ctgatactaa taatggattc ttattgcatc
    17281 ctaatgtttt atttaagtct ttttctaaag tagctaaatg ctcttctatt tcttttatta
    17341 tctctgctct tatactttca ttgttaacat aataatcatt acatgcttct gttgttatag
    17401 tgaatccagg agggacaggt aagcctatct tagtcatttc tgctaaattg gcacctttac
    17461 ctcctagtaa agatttcatg tctttgcttc cttcaccaaa actataaaca tacttagttt
    17521 ccattgttaa atcccccatt aatcttttta ttttaattta tatcattttt attaatagac
    17581 attattaaat ttctatttct ttgtatatct ttagaccatt ttctttcatt atgtctaaaa
    17641 ttatacctgc tgtttcttct attgccttat ttgaaacgtt tattactggg catccaattc
    17701 ttttcattat ctcttctgaa taatctaact cctgaagtat tctttctaaa ttagcgtagt
    17761 ttgctttact ggacaatcct aaagctttta atctttgggt tcttatctca ttcagctttt
    17821 caggtgaatt agtaagacct attatttttt tagtatctat ctcaaacact tctttaggaa
    17881 ttggtatttc tggaactaat ggaacattag ctacttttat atttttatta gctaaataca
    17941 tactcaaagg agttttagat gttcttgata ttcccactaa aattatgtct gcttgaagaa
    18001 cacctctagg gtcttttcca tcatcatatt tcactgcaaa ttctatagct tcaactctct
    18061 taaagtaaga ttcatctaat tttctaatta taccagcttc tcttttaggt tttcttcctg
    18121 ttctcttgct tatttctctt agtatatctg tcattaaatc tatacaacta agaccttctc
    18181 tttcgcaata tctttcaaca atactgcata attcttcatc aactaatgta tatacaatta
    18241 aagcgttttc agcttttgca ttctccaaag tttcaagtag tactccttta ttaatcatgt
    18301 atggaaatct ttttatttca taagtttcat tcacataaaa ctgagacata catgcctttg
    18361 caacttgttg tgcagtctcc cctactgaat ctgatactgc atatataatt aggtttttca
    18421 ccagcatacc tccttaattg tcaactattt ctaagaatag cttagttatg ttggtttttg
    18481 atattctccc aacaactctc atatgatttt tgtcttctcc cttatattca acaatcggaa
    18541 tcgaatctac ttcatgttct attatttttc ttgaagctaa taaaacactt gctcctttag
    18601 ttaaagtgac tacatttgga gttcttgtca ttatcatacc tattggcatt ttatttatat
    18661 cagaacctcc tatagttgct tttagcaagt cttttctgga aacaactcca cataactctt
    18721 cattctcatc tataataact atactcccta catcagataa aaacatagtg actattacat
    18781 catatatact ttcatccttc ttagctagta caggcatgct cattatatcc tctactgttt
    18841 tttcttttac acttttacca attaaattta tttcactaac tcctgaataa aaatatccaa
    18901 cttttggtct tgcgtctaat attcctgtca ttgttaatat agctaaatca gatctaagtg
    18961 tagcacgagt cacattcaag ctggaggcaa tactttcact cgttattggt tcattttcct
    19021 taactatatc tataattttt agttgtcttt cattaagctg aataataatc accttctttc
    19081 attgtgctat actttttatc ttttcgcatc ttatatagta tattatataa ctatatatac
    19141 cattctgtaa acagattttt tattgaatac gatatatttt ttactaagtt ctctcgctta
    19201 aagatattta ttatatatta atgggggata tttctttaat taatagaact atattagtat
    19261 tacagttaat attataatac ataattggtc attttaattc attttatatt aaaattttta
    19321 ataatattat ttcaatgtga atataaaatt gcagaactaa ttcaaaataa tttttacgac
    19381 tacaaataac ctataatata cttttaaaga aagtatccta acaagaatat ataaaaattt
    19441 aaaagggttg atttaaaaat aaccatcaac cctttttact aatatctatt tatattacca
    19501 tcaaatctta cccaaatatt ttttcttgca attgtcttaa atgatataaa gtagtatctt
    19561 tttctatctc taccatatcg taagttataa cttcaccttt tttaatatct tttacaactt
    19621 tagtcttttt acttatcaaa ccaataggta cagcattcat agcctttgct acatcgtatt
    19681 tttctatagt accatagcat gtatatgctc catagccatc cataaactca ccttttttca
    19741 aatctttctt agctatagtc ataacttctg ctactagtcc agctttaggt actattgtag
    19801 ccttatggtc taagactgcc atagctgctg ataaaggagt ctctaaacta cataaatgat
    19861 atggtctata taatatgtaa ttaggtccat cacccatact taaatatttt agttcatcat
    19921 taactgcttt taatttatgg gctactacta cgaaaactcc aggtgctata ccatttacaa
    19981 aatcaactac accataatta tctaatactc caccttcgct ttttaatgca tatttcttag
    20041 gtacttcatt aactgtagct tcaataccat gaccacctct tacatcaggc acaaatccag
    20101 ttgcattaca cattaaagcc atttctacca ttgttttagt tccttcttta aaagaagcta
    20161 tcatatgagg tgaagctcct tttctttctg cttcttctct aactgtatca ggattacaat
    20221 ctaaatctaa tttattattt ttacctttac ctatcactct aacttcaaac cccattgcat
    20281 ctgcaaaatc aaataattcc attactgcac ctggctcatc tcctgcagaa cctgtaaata
    20341 ttactccagc atcatctgct aattttttaa gtattggtcc aacaacacaa tcagtttcag
    20401 catttaacat aactatatgt tttttattta aaatagagtt taatgctatc tctgcaccaa
    20461 ttgcaatacc tccagttgca tctataacta catctattga cttagtttta caagccacaa
    20521 gaaaatcatt acatgtcaat acttttcctt cttgtaattt tatttctgca tccttttcat
    20581 ttgttacatt atctataatt tcttcatcta ttcctgcatc agtaaaagct ttatgagcca
    20641 actccaaatt tatatctaca acaatagaag cttcaatacc tttcatattt gccatttggc
    20701 ttaccattcc atttcccata tgcccagctc ctataagagc tacttttatt tttttacctt
    20761 cctcttccaa ttttgcaagt tttctgttta aatctaacat accaattcct cctgttataa
    20821 taattttatt ttcaaattaa gaaatagtta ttaaatctcc aatagttata tctggatttc
    20881 ctatttccac atgtatttct cctggtaaat ttacttcaca ttttccatca aatttgattg
    20941 tacaatgccc aatttctcta agagtcttct gagcaatatc accaactgaa actatacaat
    21001 aatctctatt ccctatagta agtgtatctc ctatttcaac atcacttttt aacgttgcta
    21061 ttgaatgaat tacagatata tcctttaagt cgtcatcatt aatggtttca tcatatataa
    21121 taagacaatt gctttcatcc attaactctt taactaaact gcctatccca cttatcttaa
    21181 cttcatattt catgacattc ctcctgataa tttatattta tattgagtta attaaaagaa
    21241 acatttattt tttcttttat aaattttata gcttgtacaa tactctcttc atctttaaat
    21301 ttttgctctg cactatatat atctaatcct tctatttctt caatctcttt aaatttagcc
    21361 attactgtac gtccttttaa aatttctcca aactttataa acccatctga atctgaagat
    21421 ataatggcta tacttccttt agaaaaatag cttttctttt tgcctgtaga cactatatca
    21481 cccttttttt tagctctatt taaagtttta aaatacaatt tattctgctt cattataaat
    21541 atagtattta aaatataagc aacaaataaa atcactaata atttcatatt tatacacctt
    21601 ccaaaaatca cattattttt aaatctgtat aacaactata aatgctgtac aatagttata
    21661 taaggttttt aagtaacacc tttttaaatt ctaaaaaagt tctacattta cttatcttat
    21721 tcgttaattt tacatcttgg cctatcttta aaacttcttc ataaattttt actaataagt
    21781 ctgagtctat cttattctca catggaaaca ttgtcataag aattattttt atacttctat
    21841 ttgcatattc tattggttct tctaaaattc caactgccat taaaaactta tctgattttt
    21901 catttacaga atgaggaaat aataaacctt tatcaaatac tgtgggagat ttttcttctc
    21961 tattgactat attttttcta aacttatcat caatgcatcc taaatccata agatggtcca
    22021 tcattttttc taatgaagca agtatagtct tttcatttaa tatcataaat ttatcttcat
    22081 ctaacaaatt atttattagt aaatttgtag aattagtagt gtcaatattc ccttctctta
    22141 ggcacaatac tgtttttaat tgttctctta gtttgttttc atcaaatatt gtatttattt
    22201 ttaatactat tgtatttata tttgatgtgt ctaaatcaat agttgtaaaa actatatcat
    22261 attcatctaa gttaatattt ctcaaattaa aacttgaaag agtatcaatt ttaggattat
    22321 ttcctatcag tttttctact cttattttca atagttttgc tgttcctaga cctgtactac
    22381 atataattgc tatttttttt attgaataga atctactgct atttctttct aaatatccac
    22441 tgaaatggat tgctatatat ccaatctcat cttctgaaac ttctaagtta tactttttct
    22501 ctattacttt tcctgctatt tgtgctaatt taaatggaag tatataattt tgcttaatct
    22561 cttctaacaa aacatttttt aactttatat taaataatag cctgtttaaa gtaaaactaa
    22621 gatgatatcc tagacctact cttaattcat cctcatttat aaaaataccc atatcgacat
    22681 atatttgatt aaatatattt tccatcaact catcaatgtt tttactaatt ctactactat
    22741 ttaaagcaca ttctgatgct ggtgcatttc cactaactaa cggtatagtt aaataaataa
    22801 tttcttcatc atttaaagta cattcaaaca ttcctgatat tatatgtttt atttccctag
    22861 caataaagta ttcatcatat gatttaagta aatcaaactt tacatcataa tcttttactt
    22921 tcttttcttc ttttactcta tagactaaaa ctactatgta gttaataact tctcttaaca
    22981 tttcatctgt aacataaaaa ttattttttt taaataaagt caatagtttt tcttctaaat
    23041 ttatgatttc ttcttttttg attcctttaa aatactttga attactgaaa tctttccttg
    23101 agtttttata caactgattt aatataaaca gtctaatatc aagttcattt ccatttaatt
    23161 tcatacctgt attctgtttt ttaatcaagt ttaaattata tgaagccaaa actttttcta
    23221 catactggaa atcatttact aaagtagttc ttcctacaca catctcatca gctaaactat
    23281 caagtgtaat aaatccatct agttctatca agtaatttag tataaactct actctatctt
    23341 cttttgaatt taatgaaaat acattttttc tattcatatc aataatctta ttgagtatct
    23401 gctcatcttt tatttctagt ttatagcctt gaccctttat atatttgatt actgctatat
    23461 cattacctaa atctttattc aattgtttta tatacgtcct tacacttcta gttgtgacat
    23521 tcaattcatt tgctattgag ttaatactca caaactcttt tttactacac ataatcaata
    23581 tcttaaatat cttgcggtca atagaaggaa ttttctcagt tacactcatt ttgtatctcc
    23641 tccttgattt cattctagta caaatttgaa accaaattaa tacataaaat ttcactttaa
    23701 taaaggaaaa tttagtatta atctaactcg ataattacag ctaattaata gtataaaagc
    23761 tagtctttca ttaacaaaaa atcttgacta gcttaaattt atatttacaa ttttattaat
    23821 taattccaag ccttatattg acattaaata ttatctcaat gcaaatactg caactccata
    23881 tgcaataata acagctattg gaccagttat taaacgagag taaaataaag ctggaacacc
    23941 atactctaca gtttctggtt ctgcttctcc caaacttaat cctactggta caaaatcaca
    24001 tccagcttgc ccatttattg caaataaagc tggaagtgct aaatatgctg gtattgcacc
    24061 aagaccaatt tgtgtaccta caagagtccc tactacttga gctataactg caccaggtcc
    24121 tagtattggt gataagaatg gaagtgtgca aattactgat ataatcaata atccaccaat
    24181 attacctgca agtggagata taactcttgc aatccagtct cccagtccag atgctaaaat
    24241 aattcccata agcatactta caaatgccat aaatggtatt acgttattca ttaccatttg
    24301 gatagtatct cgacctgcat cataaaattt tgatactact tgccctgccc cttgaccaat
    24361 agaaagtatt atgttctttt tagcatattc accttgtgct tttgacttaa cctcatcata
    24421 attatcaggc tttctaatag aactcttatt ttcgctttta ttttcttgag atttttgtgg
    24481 catatcttcc ccatctacaa cacttataca gttaggatta acatctgata cataatattc
    24541 ttctgttata aattttgcta aaggacctgt ttttccaact ggatttacat ttattgtagg
    24601 tatttttttc tttggataaa ctccacatct agcagttcca ccacaatcaa taataactac
    24661 tgctacttct tcatcagaaa ctccagtttt aaatccatct acaatttcac aacccagtag
    24721 ttcttttatt tttaatgtta cttcatggat accaccagca gtcattgaca gtatcttatt
    24781 tctattccct tcttttttta tatacaaagg acctccccag cctgaagttc ccttttctat
    24841 ttttaatatt ttattctcct ccattttatc tacctcctaa gccttatttg ttgctctatt
    24901 ttttcttgtt agaaaagcat acattttttc tgttactata cctcttataa aaattacaat
    24961 tagaccaact ataaaatacc acaatgccaa tgtagtagtt tctttaccta aagtagtcaa
    25021 acctgcagat attcccaacc atacaaaaag ttctcctgca tttgcatgtg gaaaaagacc
    25081 tgtaattgga tgtacaaatg aaactgctgc atcataaaat cctgctttgt gctcttcttt
    25141 taaaaatcta ccaaatgtat agcacatagg atttcccaag aaaaatactg atactaatgg
    25201 aagtagaata tatcttgtaa aagagttctt tcctagctta gaagcccaat tattaactct
    25261 ttcctcacca attatcttaa tcaaagagtt aatagctacc attaatacaa ttagcgttgg
    25321 aagagtacct gaaacaagac ctataaattg ttctccccct ttctgaaaca aaccgataaa
    25381 ccactctgca cctttactta gacctgtaat aacgttttcc ataaaattat aacctcccta
    25441 taatatcttt aaatttttaa ttttactgct taccataaat tttacaaatt acatcttttt
    25501 tctgtactat atgctaatat tgtaaatgtt tttttattaa tatcatttta atataatatt
    25561 tttgataaat aaatacatct tttttcaatt ttataaagga aaaaattgta ctaattagaa
    25621 ttttcagaaa tatacaattc ttatttcgac tatattctaa attcttctta gaaatttaag
    25681 aacttatttt tatttctttt attattaaaa ttatctaaat ctgataaaaa taaaaaatag
    25741 atgctctttt acgaacatct atttcttaat caaattattt tttagttttc ttatagatta
    25801 ttttataggt atataaatat caatttgtga gttcacatta ctaggaccta aaaatcgttc
    25861 atcatatact tcaaaatcat ctcttatatc aagttcttct tttgaactta aaaaccaagt
    25921 accccatata tattcataag ttttgtctaa attatctaag ctaccagtat gagtaaatat
    25981 agcatacttt ccttccttaa tagtttttga aacaaatgaa tttggaatca catcataact
    26041 attaacttca agtcctatta tctcattaaa ttccatactt tcactaacta ggtgtatttc
    26101 agagattgct tcacagattc caaaaactct ctttgatggc aaagtatttg ggacaatatg
    26161 atgtactttt ctgaatttct cccacaagtc aggtaatgaa ttattttcta aaattacttt
    26221 atcctttata cctattacct ttattttttc tatttctttt ataactggtt taatcgttat
    26281 atttccaaca agatgtctca taaaatctaa ctctaatttt ttctttttac caacaaatac
    26341 atcaattcta ttttttctat attctatagg gctaaccttg tatatagatt taaatgctct
    26401 gctaaatgct tccgaagatt caaatccact accaatagct atatctatca cttttttatc
    26461 actatataaa agttcttttg tactacttac taatcgtctt ttttttatat aacttcctac
    26521 actctcacca aacatagact taaataagcg tgttaaatga taataagaat atccagtttc
    26581 ttttgccaca tcatttacag ttatattttc atgtaaatta ttctcaatat acattacagc
    26641 ttttttaaaa tactttaagt aatccaatat ggcacctctc ttctacttaa actctttaaa
    26701 tatgtaaaat agcactattt tttactatac taaaatatta taactaattc aatacgataa
    26761 ataaaaactt ttagttgatt tatatatcct aattatttag aataattaaa tacatttttt
    26821 attcaatgaa atcaaaaaag tcagatggtg ctttttcaat atttatgttt atcctctgtg
    26881 ttatagattt aatgtcattt tttaaatagt agctctccca tttattctct agtccacccc
    26941 ataaaatatt aaactttcct atatttaaat ccataactat actttttaaa gttccaaaaa
    27001 aatcattata gtaattacaa gataagccat ttggatattt tgaagacaat aaattcatta
    27061 actctttctc tccaattttt ttagacttat ttatatattc tttaattaat ttatatctat
    27121 gaatagaatt tttcattgat tgtggctcta atttatgaag tttatcaata tgtgtatgat
    27181 tagtagagtg taaaaaatat tctcttttac tttctaaact attgattata tttacttctt
    27241 ttttcccatc taaagtctcc acaagtgcaa tgtttccaga cttatctgca agcaataaat
    27301 taatattgta tgcaattggc atatctttta aatattctaa tgcttcatct acatctttgc
    27361 aattttctaa caaatatcta ataacagccc aaaactgtaa acctacaatt gctggttttc
    27421 ttaaaccatc tgaattgcct acaggaatac cacatgatga ctgacttaca cctaagccac
    27481 attcattcat accttcacct cttccaaatt gcataacggt agtacctata tgtgcatatt
    27541 ttccatttac cttagtttta cataaaacaa aatcctccat attgtgtgag aaatcgaaat
    27601 tacgtgcaaa tagtacatgc ccattttcag ttaattctgg tgctaatgca acttgactac
    27661 aacctggttt aagataagtc atagtataat ataaaatttg attacaattc acttgaattg
    27721 catcagcaaa accttgcaat tcttcattaa gacctggaca atatttatca aacaactcta
    27781 tcatctcttt ttcttctttt ttgcttacca gattagattt attaatctga ccttctatta
    27841 tctctggcat attagcaacc aattctccta gtctgtatcc tatctcataa tttgtaccac
    27901 tcaattcaat atttcttact tctaaagttt ccatatgtac ccctcctata tatcttataa
    27961 tcgattttat cattcgaatt gtaatcattc atgatatttt gtgctacaag ttaaaaaagg
    28021 tcatataaaa acagataagc ctctttttca ttgttaaaat aataaaaata tatttaattt
    28081 catacaaaaa agagtgtctc ataaactaaa aagttcattt tgagacactc ttcttatttt
    28141 aaagagtata attaaaaata gtctaagttc tactcttcct tcattttttt caataactct
    28201 ggattttcaa ataaattaaa tcctgttaaa gctaatattt ttataccatc aattactcta
    28261 tcttttgcat atgaatttat agaagcctcc aaaaattctt ttgtatgtag ttcttctcca
    28321 ttttcagaaa acttcatcaa aggatgtata catggcatta tttgacttaa atttcccata
    28381 tctgttgaac ctaacattac ttgttcatct tcatatattc caaattcctc cataatcttt
    28441 gtaaatatgt ctaccaaaac tttattttca tttaatcctt ggcaagttgg ttcaaagtga
    28501 taaaattcaa gttcacatcc agtggctatt gcagcacctc tagcacaatt tttcactttt
    28561 tctactactt catcaaagta attttgttct tttgccctta tctctaatct tacttttccc
    28621 atatcaggta ttacatttgc agcagttcct gcttctagta taataccatg tattctcgtt
    28681 ccatctacta attgttgtct tagtgcattt atattattat atagtaatac tactgcatct
    28741 aaagcattta ttccgttata tggcttagct cctgcatgag atgcttttcc agtaaatatg
    28801 aaatctagac ctcctattgc tataatttca ggtgttacac aagtttttga atttggatgt
    28861 atcatcattg ctgcatcata gccatcaaat acaccatgtt ctatcaagta aggctttcca
    28921 tctccagttt cttcagcagg tgttccaatt atacttactt ctcccttgta agtatccagt
    28981 atacttgaaa gagctattcc agctccaact cccatagatg caattaaatg atgtccacat
    29041 gcatgtccat tgcctggaag agcatcatat tctgctataa atgctatttt aggaccatct
    29101 ccatttttct tggttgcttt aaaagctgta gccatacctg ccaagttttc ctcaacatca
    29161 aaaccctctt ctcttaaaaa ttctgatatt tttttagcag atttatattc ttgcaaagca
    29221 atttctggtt catcatataa agattgacat agccctagaa ttttttcttt ctttgaatca
    29281 gccacttgta ttattctttc tttcatacca atcttacctc ccactaaatt tatttagtaa
    29341 tttttatatt ttattataac tttaatttaa ctcatgctta tcctctttta agtatctatt
    29401 ttcccaaaac tcagcatttc ttatatctaa ctctataggg ttaaaagttc tatcactcct
    29461 ttttattccc atcttcttct gtcttatata atcataatat gcctttatag ctggtttttt
    29521 tagtgtaaag atggcaatta aatttatata tgttaataca cctatacata tatcacctaa
    29581 tgcccagctt gtaagtggtt ctataaaaca acacattgct gcacatgcta taagcataaa
    29641 tctacagaca ttaattatgt acttttcatg tttttctgct ttaattctag ttactaagta
    29701 agatacatta gtctccatca tatatgagaa ggctaataaa gttgtaaatg taaataataa
    29761 taaaactatt gctataaaaa tatcacctaa ttgtggatgt aatgtattta ttgcactctg
    29821 tacatattgt ggtcccggtt ctacacctgg cagtgctgtg caaacacctg taacattata
    29881 cattcctgtt attacaatca taatacctgt agccatacat attaataatg tgtctacata
    29941 aacagaaaat gcttgaacta atccttgttt ggctggatga ctcacttctg ctgctgccgc
    30001 accataagtc ccagaacctt ctcctgcttc atttgagtat atacctcttt ttactcccca
    30061 agatattgct gaacctagca ttcctccaaa aactgaacca aatccaaatg cagatttaaa
    30121 cattgttaca atagcctctg gaactaaact aatatttgtt ataattatta ctaatgtcat
    30181 aataaggtat gctccaccca ttataggtac tactttttca gcaaataaac caatcctttt
    30241 aattcctcca aaaattatta tcgctaatgc aatagaagat gctactgcta ttgtcatttt
    30301 tgaaaatcca aatgcttgat tcattgctag atataaagtg tttgattgtg taccaggcat
    30361 aaaaaatgta taacttatta ttgcaactat tgaaaataaa actgaacact ttttccaccc
    30421 aagacctttt tcaaaataat atggaggtcc tcctctatac tgcccatcat gctcatcttt
    30481 atatatttga gctagagtag attctacaaa tgcagttgct gaacctaatg tagccattat
    30541 acacatccat actaatgctc ctggacctcc cattgctatt gctacagcta caccagctat
    30601 atttccagtc cctattcttc cagccataga tgtagcaaaa ccttgaaatg atgatatacc
    30661 aacatgagaa ctatctcctt caagcaagag agtaaacatt tcttttacat ctcttatttg
    30721 aaaaaatttt aatttcaatg aaaaatataa tcctatacac aaacacattg caactaatac
    30781 gggtgaccaa acaattccat taatggtgtt aactaaatcg gtcacttaac tcaccaccat
    30841 tcattttata tttatagaca ataatttaaa cagctatatt tcaatatttt atataatctt
    30901 tatattaata tatctaaaaa atctaccttc tatttattta tattatcttt aatctacaat
    30961 ctacaaatat ttatttctaa aatcaagagt attaatcata tctaaacata aatttataaa
    31021 atttttaacg acgtgtgttt gaataataat caaacaatat aaattggaat acatataatg
    31081 aaaagcctga aattattatt atataaatag tacaatatat atttattaat atataattaa
    31141 atagtatcta gttagatttt aaattttcgt atttattatg aggtttaaaa ttgagtacaa
    31201 ctaccatcta tttttaaaat ctcttagaat ttaaattaaa taggtttatg taggtaagaa
    31261 aatagataat aattgccact caattttaca ccttcagggg taactttatg ttaaaaccta
    31321 gaaaacttga taacattttg atttttatac tttattctct aaacattatt ataaaactta
    31381 atctattgat attttttatg ttatttatac aatcacattc atcaaaataa gtattgtatt
    31441 tatatatact taattaccaa attgaatatt taagcttcta atttacttgc tcttctcttt
    31501 ttaaccttta atatatataa acaagatagt attccaataa ctagaattgc tatttggaat
    31561 ataaatgtat atgtgtaacc tttattgcca taagtatcta tccagtgtcc tattaatgca
    31621 aattggaata catctggtga aaatcctaaa gctgcagcta tacctatagt agttgctgaa
    31681 tatttaactg gaacttttac ttcatcttgt actgcataat atataccttt tcccatgtaa
    31741 cctaatatac ctactacaaa tgttaaagct atgaatatag tcattggagt tgatgcaggt
    31801 aatactagga ataaaactat tactgctata ccaaatacat atattggtaa aagtactttt
    31861 gtaggagatt ttaatttgtc tgcacaatat cctccaaatg gtgctccaaa taattttaga
    31921 ccatgctgtc ttattattgc taatgcacca gataatgcta cagaacctcc aagtacagat
    31981 gttatatatg gtgtaaaata agacattgta actgtgaatg aatatacaca gaatatactt
    32041 attcctacta gccaagtatt tggtgatttt agtactgtta taaaatcacc agcagacatt
    32101 ttttcacctg cttcttctct ttcttcttta atatctacat ctttaattac aaaccataat
    32161 actggacaca ttgctattga taatattcct aaagatatca ttacccatct catacccaat
    32221 gtaggagttg caaagcatgt ataaatatat aagaatattg ctcccattac tactccagaa
    32281 actccaacca tagcttcatt aaatccataa accttacctt gattatcttt tcctataact
    32341 ctaagtattt ttaccataga aggatagttc ataactaatg atgtgattgc acaacctacc
    32401 caagtagcaa ctgcaaatgg atagttcata ttaaatgcaa ataaaaatga tactactcca
    32461 ttaagaaata cagaacctaa aattatcttt ctataatcaa atctatctgc taaccagcct
    32521 cctataggag ctccaaatat attacctaac ccataaattg taagtagaaa acctagttga
    32581 gtgtttgtac attctaatgc ttttagaatt ggatcatata atgtatattg gataaatggt
    32641 ataatataaa ctaattccca agatattgct ataataacaa gttgaaacat taactttcca
    32701 aactttatac cgttttcttt ttctcccata tttaaaccct cactttttat atttattcac
    32761 aagcataatt gagttctttt tttataactt ctgcaagtat ctcaacacct ttaacgattt
    32821 gttcttctga cattgttgta tagttaagtc tcatagtatt ttttggacca ttatttgcaa
    32881 agaaggactc tccagaaaca taagcaactc cagcatcaat ggctttatct aataaatcat
    32941 ctacatttat actttcagga agttcaaccc atataaacat tcctccatct ggttctgtat
    33001 atttagcttc ctctgggaaa tgtttcttca tagcatctaa cattagcaga catcttttct
    33061 tatactctgc tcttattttt tctatatgtt catttaagtt gtatttcttt aaaaattcta
    33121 ttacttgtac ttgcgaaaat tgatttgact gtaaatctat accttgtttt aaaagttctg
    33181 ccttatctat gatgtctaca ttaccacaca tccaagcaac tctaaatcct ggacataata
    33241 cctttgaaaa tgacccaagg tacaatactt tatctttagt atcaagagat ttaagtgtag
    33301 gtagaggttc tggtgtaaat cttatttctc cataaggatt atcctctatt actatgacat
    33361 catatttatt cacgacttcc ataaaatctt ttcttctttg taaagaccat gtttttcctg
    33421 tagggttttg aaatgttggt attacatata tcacctttat gttagaattt tcagataata
    33481 atttgtctaa atcatctgtt accattcctt cttcatctgt atctactcct aaaaaatcac
    33541 attcataagg tctaaatgca tttattgcac ctaagtaact tggattttct gtaactacta
    33601 catctccctt ttctaataaa atcatagcac ttaatgctat cccttgttgt gacccagtag
    33661 ttattataat attttctgct tttgtatcaa tattttcttc ttctttcatt ctttttacta
    33721 atagatctaa caactcatct tcacctttag taggtccata tgctagggca aattttcccc
    33781 tttcattaag tactttttga gttatttcac ttatctcttc tattggaaat aaatttgggt
    33841 caggaagccc tgcagcaaaa gatataacag ttccaccact tgctaccttc tgagctattt
    33901 tcttttgaga atctcttata gctgaagctt ttaccatatc cattcttttt gcatatttca
    33961 taatactttt tcctccttaa taataatttc ttattgtgat gctaggcacg ctaatgctat
    34021 tgaatttatt tttatttcag ctgtgtcaga acgtgaacct aaaattatcg gatttgttgc
    34081 tcctaaaact atacctgccc acttagcttt attaaatcta agccatgact ttcctaatat
    34141 attccctgct tctatatttg gaaatactaa taaatcaaca tcaccagcaa tattactttt
    34201 aataccttta tgttctgctg catgtgcatc aaatgctaca tcaaatgcta ttggaccttc
    34261 cactatacac tttggtattt ctcccgattt ttccatctct acaagtaggt tggcatccac
    34321 tgtagattgt atcttagggt ctaccatttc atttgcagta agtatcgcag ttttaggatt
    34381 ttccatgcct atacttttca tagtaagaag tgcatttgtc attatatctt ttttttgatt
    34441 taagtttggc gatacattta ttccactatc agtacaataa agaagtttat gatattgagg
    34501 taattcatat actgcaagca aacttaataa tcttcctgtt ctaagacccg tttctttatt
    34561 taatatagct ctcatataga cacttgtatt tactaatccc ttcataagaa ctttagcttc
    34621 cttattttta actatctcta cagctttttt aactgattca tcgggatttt gacaacctat
    34681 tatttcatga ccttttaatc caatttctct tgatatactt tctattttat ccttgtctcc
    34741 tacaagaatt ggctttataa tgtttaaatc tgttgctgat ttcacagcct ttaatacttc
    34801 tttgtcttct gcaacagcaa cacttacaat aacaggttca agctttttag cctcttctaa
    34861 taaattatta aaatctttta acatactctt tctcctaaat attaataagt ttttgctatt
    34921 tcttctccat taagtactct aagtgcccct agagcaagtg cctccatttc catctctcct
    34981 ggtactatct ctattggagc tagatatgaa actttttctg ctactccttt gactaccatt
    35041 tctgagtgag atatccctcc tgtcaagata actctatcta cattccctga aagtgaagct
    35101 ccatacatag aaatttcttt tgctacttga taaataaatg catccattat aagttttgcc
    35161 ttttcatcac cctccttgat tctgttttca atttctatca tatcctttgt tcctaaataa
    35221 tcgtacattc ccccaatcga acttactttt gcgaccattt catcatgagt atattttccg
    35281 gagtaacaca attctataag aggatatgca agtaatccac cactcctttc tggagaaaat
    35341 ggaccatcag acctaccacc acttccatca atcattttgc cttgtttatg tgctacaatc
    35401 gatattcctg aacctaaatg agctacaata aagttataat cctcgtattt tccccctagt
    35461 ttttgtgcaa tttttcttga aacagcttta tggtttaatg catgtaacca acttgctttt
    35521 tctatgtctg atattcctgt aatcctcgat acatcatcaa attcatctac agaaactggg
    35581 tctactacaa atgattgtac tcctatttca tcagctatag ttttagctaa taatgcacct
    35641 aaatttgatg catgttcccc atttatttca tttctcatat cctcaatcat ttcttcactc
    35701 acagtatagg taccaccttt tatagccttc ataagtccac cacgaccaac tactgcgtca
    35761 aaagaattta tactatgatt ctcactactt aaaatatcta ctatcagttg ttttctataa
    35821 tcatattcat caaatacttt agaaaaattt tttaaatctt ctcttgtatg ggttatattt
    35881 tttttcaaaa tttcattttc atcttggaaa acagaaattt ttgtggatgt accaccagga
    35941 tttattacta aaactttcaa tttaacaccc cctagttcta ctatacagaa cgtcgttctt
    36001 gtattccgac ctaaagactt cgtcctattg ttcagaacga cgttctatat tttattaatt
    36061 aaatactaac atataaaaat aagtatttca ataattattt taaatattta aaatattcat
    36121 tcgtagtcgt atccagcttc aaatgcttct acatttttag aattgaattt acctttgcct
    36181 tgattttcaa agtattcaca cataccactt tcaaattctt cttttgtaaa taaatccaaa
    36241 ctctttacca tagcacctaa catgcaaatg ttagcagctt tttcattgcc taaattttgt
    36301 gctatttcag taacaggtac ttttataaca ttaatgtctt ctctgtactt tctatcctta
    36361 cttactagtg attcattgac aaacatataa ccattttttt tcattaaact ttcatactta
    36421 tctactgata cgctgttcat tcccaatagt atatctggat tttttacaca aggatttgca
    36481 attttttcat cacttacaac aacattgcaa tttgcacttc ctcccctcat ctcatttcca
    36541 taagatggga accatgtaat tttcttttct gccttatatg caacatacat tataattttt
    36601 cctgctgtaa gaactccctg tcctccaaaa ccagcacata taatttcatt caacatatta
    36661 tttcctccct aatcaataaa ttctccaagt ggatactttg gaacaagttc attttcaatt
    36721 ctcttcatag catctactgg ctttaatccc cagtttgttg gacatggtac aagcacttct
    36781 attaagcaaa aacctttctt ttctttttgt ttttctagag cttttttgat gtatcttttt
    36841 gttgtattta tttctttagg gttagttatt gttcctcttg ctagatatgc tatatctaaa
    36901 tttcccataa cttttacaac atcaaatgtt gaaccatgat ctgcgtaatt tctacccgct
    36961 ggagtagaag ctgtatattg accttctata gtagttggag ccatttgccc tcctgtcatt
    37021 gcaaacatat tattgttcat aacaagaaat attacattat catttctagt agcagctgac
    37081 atagtttctc caagccctat tgcataagct ccaccatctc cagctattgt aaatatatat
    37141 ttatctggtc taactctttt catagctgcc attgctgctc ccattttacc atgaggtgga
    37201 acgacaacat ctacattcat actaaattga aacatatgat tacaacctat atctgaacat
    37261 ataattgtat cttgacatat atccatttct gttaatactt ctccaataat tctatcgact
    37321 atagagtgtc cacagcctcc acagaacata ttttcacaca tcattattgc tggtgctttt
    37381 ttagccataa ttaaaatacc tcctcttgct tagcttttcc atctataatc tgttgagcaa
    37441 aatctattaa ttgatttact tctgccatat attgagctgt tgctactgaa tatactggaa
    37501 atctattatc acatgctata attacatctt ccttcatctg tgccatcatg ttcatttcaa
    37561 ctgttacaag tcccttcaat gaatcactta atttcttaaa tgcttttctt gggtaaggcc
    37621 acaatgtttt tggtcttatt agacctaatt tcattccttt tgctctagca tctctaactg
    37681 caccttctgc tattcttgat gaaataccgt atgccacaaa taccacttca gcatcttcta
    37741 tttctatctc ttcccatctt tgttcatctt cttgaacttt tctcattttt tctatatacc
    37801 ctttttgcca tgtatcttgg tcttcaaaat atgttatatc agttattact ttattttttt
    37861 ctcctacagg tgttcctttt gcagcccatg gagctttatc catatcgtat tctttcattg
    37921 gtggtgctat acaaggttct accatttgac ctattgtagc atcagaaagt ataagtactg
    37981 gatgcatata tttttcagcc aattcaaaag attcatatgc catatccata ttttcttgaa
    38041 cactattagg tgctaacacg attaaatgat aatctccatt tccaccgcct tttactgctt
    38101 gccaataatt atcttgacca gctcctataa atccatcacc tataccatat ctttgcacac
    38161 atgctacaac tgctggcaaa ccagctgata cccaatatgc aataccttct tgttttaatg
    38221 aaaatcctgg accagatgaa gaagtcatag ctcttgctcc aagtgcactt gctcccataa
    38281 ccatatttac actggctatt tctgattcac cttggataaa tactcctcca acttcttttt
    38341 gtctccatgc catcatttct aatatttctg attgtggcgt tattggataa cctgcataaa
    38401 atctgcaacc accacgtata gcaccttctg ctaaagcttc atttccttta attaataaac
    38461 tttgcatacc ttttctcccc tctaataaaa ataatttata atatctcaaa tactaaatca
    38521 gggcacattg tataacaagc gccacattga atacattttt cttcatcgac tttaatagtt
    38581 acaaagcctt ttttatttgt gtagtcagaa agacttattg catctttttt gcaagcttca
    38641 atacaaagat agcatccctt acatctttca acactcaact tgactttttc catttctcaa
    38701 atctcccctt tatgtaatat ttttacttaa ttttaaatat ataatattta tattttgtat
    38761 aaatactata tatgcatcaa ttttgttcta tagtatagaa ccttgttcta tttttattgc
    38821 ttaattaaaa gataacacat tcgcttatat atttcaataa cattttaaat tttaagaata
    38881 tttaatttta gattaaagaa aaataggcta catttaaact gatatttaca aataacaatt
    38941 taaatatagc ctatttttat tatcgagatt aaaaatcatc taaaaagttc agatatactt
    39001 tttgcagttt ctataactct tttaatctta tactcaaagt ccccttctct cattcttata
    39061 gttggacctg acaaacttat ggctgcaata gctttattat ttttatctaa gataggtgct
    39121 ccaatacaag ttagtccatg ttctagttct tcatcatcta tagcatatcc ttgttctttt
    39181 atttttgcta aaaaaagcat catatcatcc caattatcaa ttgtatgttc tgtatacttg
    39241 tgtattggtg tttttctata tttttcaaaa tctatagaat cattaaatgc cataagacat
    39301 ttaccaactg ctgaacaata acattcacta cttgaaccaa cggatggatt tactgaaagt
    39361 aattgatttg aaccatactc tttatgtatt atgatacttc ttggagaatc ttgagctctt
    39421 tcttctaata tagatacatt aactacttcg ttaaattctt gatttaattt tttcgtatat
    39481 ggttttacta tttcagtcaa tgacattttt tctcccacaa ccatacctat tgcatataaa
    39541 tttattccta gccaatactt accattctct gcattttgta taacaaaacc tttgttttca
    39601 agagtaacca aagttctatg tacagtactt ttatatactc ccatagcctt acttatttca
    39661 gttattccca tttctctctt ttcatgatat aacagcaaaa ttatgtctag ggctctatct
    39721 aatgcattta ttatttctcc catatacaaa aactcctcct gcaaatatta agtgctactc
    39781 ccacactcta ctaaatatta tatattaaaa ttacaaaatt atctatttat cttaattata
    39841 ttttataaaa caaaaatatt atacttaatt tgtaaaataa aaacaaaata ctcactatgt
    39901 ccttattatt cttactttta atagaattat tctgttatat ttttatcctg actagataat
    39961 aatatatata tctattatac aatagatata tttttataca agactaacaa tgaggtgaaa
    40021 taatggataa ttttaaaaag atattgttaa atgaactacc taattttaaa gaatattctt
    40081 caaaattttt aaatggagaa ataaataaaa tgcaatataa gggattttct ggtggatatg
    40141 gtgtttatgc tcaaagagac aaaaaatctt ttatgataag acttagagta tctgctggag
    40201 ttttatctca gtatcaactt aataaaatct atgaaatagc tattaaacac aacttagata
    40261 agatacactt aacaactaga caagctatac aattacacga tttatctata aattcaattg
    40321 ttgatatcat ggaagaagga ataaaaaatg atatattcac tagaggtggt ggtggtaatt
    40381 atcctagaaa tgtcggatta tctccattat ctggagttga ccctagtgaa gtctttgatg
    40441 ttactccata tgcagttgct actgataaat attttatcaa aaatgctact acataccatt
    40501 tacctagaaa attaaaagtt tcttattcta attgttacac agatactgct cattgtagta
    40561 tacaagactt aggatttgtt gctactttga aaaatgatga accatatttc agagttttct
    40621 taggtggagg tctaggtaaa caacccaaag ttgctttaga acttgatgaa cttataaagc
    40681 cgaaagacgc cttatattgt gttgaaggta tgattaaatt ctttatggat tatggaaatt
    40741 atgaaaataa aaacagagct agggttagat atatggtcga atcacttggt gaagaactat
    40801 tcttagaaaa atttaaagaa tactataaat tagaaaaaga aaatggtagt cttgaactca
    40861 atattgaaga aatagattac tctaaacctg gagttaaaat agatatacaa gattctagac
    40921 taatacctca aaaacaggat ggtttataca ctgtatatat acatccagtt ggaggtattt
    40981 tgttaacaaa ggatttaagt actttactta aagaattaga taatgttgaa aatcctatga
    41041 ttagactagg aatgacagag ggattatata ttttaaattt aaatggaaat gaagcaaaaa
    41101 gaatattaga aataagtaaa actattagtt gtaattctca attagaacaa agtatatctt
    41161 gcataggtgt tccaatttgt caaatgggca tacaaaatag tcagaaaatg ttacatgaaa
    41221 tcatagatta ttttagatta caaaataatg aagaaatttt aaataaagca cctaagttat
    41281 atatatcagg atgtttaaat tcatgtggtg ttcatcaagt tggtagcata ggtttatgtg
    41341 gtaaaaagaa gaatgttgat ggtatatcta cagatgcatt tgaattattt gttggaggca
    41401 gttttgaaat aggtaagact agattgggaa aatcacttgg agattttaaa gctagtgata
    41461 ttcctgaaat gctttataaa atatcggacg catcttcagg caatttttat gaatgggtaa
    41521 attcaaatga taatatttta aacaaaataa ctgataagta taaaatataa tttattatat
    41581 ttacttacaa aaaacatggg tgtctcaaaa tgaacttttt agtttatgag acactctttt
    41641 tctatgaaat caaatatatt ttcatcatct caacaatgaa aaataagact atctctattt
    41701 tgagacagcc ttatttctta taaatagttt aaattttatt tataaacaat tttagataaa
    41761 tcacaaattc ctagcatagt atcatatact tgtttaagta aagcaagtct attgttctta
    41821 atagcttcat cattatccat gaccataact gtatcaaata aattatcaac tactggtctt
    41881 aaagatgcaa attcatctaa agcaatacca tatttcttat cctttaataa ttcattaact
    41941 tttaccttta cttgtttaaa ttcattgtaa agtttaattt cagcatcttc ttttaataaa
    42001 gattcatcaa ttttatcact ttctgctttt tgagctagag tagaaactct attaaatgca
    42061 gtaagcatct ccactaattc atctttttct agccaattat taagctctaa agctctcata
    42121 tgcatatcag aaacatcatt tatatcagaa cttaaaacag catcaacaac atcatatctt
    42181 attcctaaat ctttaaatag attttttact ctctcattga agaaattcat tatttgctca
    42241 acaacttctt ctttattaaa atctaattca gaataattgt ctaaagcatg ttcaataagt
    42301 atttttatat ccacagcaac ttttctgtcc ataagtatac taagtatacc taaagcttgt
    42361 cttcttaaag catatgggtc ttgagaacct gttggttgta ttcctatagc aaagaaacct
    42421 gctattgaat ccaacttatc agctattgat aaggcaaccc ctgcattagt cttaggaagt
    42481 atatctcctg caaatcttgg aagataatgt tcaaaaatag cttcacttac aacatcattt
    42541 tctcctccaa cttttgcgta ttcttttccc ataaaacctt gtaattcatc aaattctcct
    42601 accattccag taactaaatc tgccttagat aatttagcag cccttatagt atctgccttt
    42661 tcatctacta aacctaaact atcaagtata tcagcactta atttttcaag tcttaaagtt
    42721 ttgtcgtaaa tagttcctaa ttttacttgg aatacaacag tttttaattt ttctatgtag
    42781 ctttctaagt ttctcttagt atcttctcta tagaaaaata aagcatctgc aagtcttgct
    42841 tctaaaactt tttcatttcc agctttaaca ttgtctattc tgtaagaatc accatttcta
    42901 acagctataa agttaggtaa cagttttcct tctttaagta ctggaaaata tctttgatgt
    42961 tgtttcatag gagttataac aacttctttt ggtagtttta tataatccac atcaaattct
    43021 ccataaaaag cagttggata ttcaactaaa taagttacct cttcaagtaa atcttcatca
    43081 aattcaactt ctccacctaa agaatttgct acttctatac attgttttct tatcatttct
    43141 tttctcttgt tttggtctaa aactatataa tttttttcta atttttcaaa ataatcttct
    43201 atagaatcaa cttctattgt actttcacct aaaaatctat gaccttttgt tacattagaa
    43261 gatattattc cttctaaatc aaactctaat actttatcat ttaacaatgc aactatccat
    43321 cttataggtc ttgcaaattt aagatttttt cctccccaac gcatagcttt tgggaatact
    43381 acagatttta tagtctctgg taatatgtct tttagtactt ctgaagtttc ttttccatct
    43441 tgctttatag tcgcaaatat atattcttct tttccaactt gtttaaaata tatgtcagat
    43501 tcgcttaatc ctttgctttt tataaatcct aatgctggtt ttgttaaatt attttctgca
    43561 tcaacagcaa tttttttagc aggacccttt atttcctctt ctaaatcact ttgtctatca
    43621 ctcaatcctt cgactactaa agtaagtctt cttggtgtcc cataagcatt tattttatca
    43681 aaagctattc tattttcatc aaataattta ctaagattgt tttttaattg ttctagtgta
    43741 ctgcctacaa atcttgatgg catttcttca acaccgattt caaataaaag ataatttttc
    43801 attatttgtc accgtccttt aaaagaggga atcccatttc ttctctttgt tttacaaaag
    43861 tttctgcaac agtctttgcc atatttctaa ctctacctat aaatgaagct ctttgactaa
    43921 ctcctattgc acctcttgca tccaatgtat taaatgcatg agagcatttt aacacatagt
    43981 catatgacgg tattacaagg ccattttcca taagtcttaa tgcttctttt tcatatatat
    44041 caaacagatt aaacaacata tctgcatcac ataattcaaa tgcgtacatt gagttttcat
    44101 actcagcttt attaaatact tcaccataag ttattttatc attccatttt aaatcataaa
    44161 cactatcaac ttcttgaatg tacatagcta atctttctaa tccatatgta atttctcctg
    44221 tctcaagctc acattcaata ttacctactt gttgaaaata cgtaaattga gttatttcca
    44281 taccatctag ccaaacttcc catccaagtc cccaagcacc aactgtagca gcttcccagt
    44341 tatcttcaac aaatcttatg tcatgctcac ttgggtcaat tccaatctct ttcaaacttt
    44401 ccaaatataa ttcttgtata ttatctggag aaggttttag tataacttgg aattgatgat
    44461 gttgatatag tctgtttggg ttttcaccat atcttccatc tgctggtctt cttgaaggct
    44521 ctacatagca tacttgccaa ggctcaggtc ctaatgatct taaaaaagta ttaggattca
    44581 tagttcccgc acctttttca atatcataag gttgcatcat gatacaacct tgctttgacc
    44641 agtatttttg caacgccagt atcatctctt gaaaattcat aaaaatccct cctataacaa
    44701 taaagcctct cgtctacacg aaaggctatt ttaatagttc ttctacaact tttagaatat
    44761 caaattctat aaaatttgtc aatgttagtg ataattctta taattatctt ctcttcattt
    44821 tttaaaagtc actttatatc tatttatttt cgtcttcgtc ttctttattc ttttcagatt
    44881 cttctttcat aaggtcagca gttacatctt tgtcatcttc ttttttgtca actactacat
    44941 ccttcacatc ttttgctgca ttagttatca tattcttcaa aacgtgaagt ttttcttcat
    45001 tcaattcacc taaatctaca atttctccat cttcttcatt ttgaactttt atacgatatt
    45061 tacttataac agcagctgat aatccaacta aagtagctaa tggtacaaaa gctaatccaa
    45121 caactccaac tgttaaagga atattcatca tagtttttcc atctttttca actattattc
    45181 tcactacact actttttcta agaagctctt ttaattgaaa ctttatattt tctccatctt
    45241 tgccaaatac ttcttccata gtttctttag cagattttgc tttacaatta caagtatttt
    45301 ttttattttc taaatatatt actgcctcaa ttacatctcc attgcacatt actaatgctt
    45361 cttttgcttc tgcataagtt gctcctggaa ctctttcaaa gactgaatca accatttcaa
    45421 tagttatatt actactcatc attatccact cccttattat tttttacact ttgcaatacg
    45481 tgtaatgatt taaaattaat attatcaaca taaactttca aatacttgtc tagaatattc
    45541 tcaagttcat gtgttatata ttttgatact ttagctttac tacatgttaa aatatcattt
    45601 cttaatacat attccataag acttatagtt gttaagtcta attttatatt attatcaaaa
    45661 agtttactac acttactaca tagtatacca ccttcgtaga tattaaacac agaattttgt
    45721 aaaattttac attcacaatt aatgcattta tttactatag gtttaaatcc tatatagtct
    45781 aaaaatttta actcgaatgc tgctgttata aacctattgt ctgtattatc ctgtgtatac
    45841 aaatacagag tctgcgcaag taatataaat agcctattat tagtctgatt ttcaagtata
    45901 gaattttcaa ctaattttgt aatatatgta gcataagaaa atgcctctat atcataggat
    45961 atattataaa aactttttat tatttcactt tgagtaacct tgtacatatt accttgtttt
    46021 tttaaggtaa aattgctata agaaaataac tgtgatgatg aaagcaaaga gctcttattt
    46081 tttttagctc cttttgctat tgcagatact tttccaagct ttcttgtaaa tagtgtaagt
    46141 attatatcac tttccttata ccttatagct ttaagtacta tcccctgggt gttcaggatt
    46201 atcatcgtct tcttttttct cccttacttc ttcaatttct tcatgtatgt ttttgcaatc
    46261 acagaaatat aaatatgcat ctatactacc tgttttttta aaaacttccc aactgatatt
    46321 gttcattttt aaaaaacccc cttcttacat ttatacttat atttttagta agaagaggat
    46381 aaatcataca taaagttatt aaacaatttt tgacaataat gccgttgtta ttataaagta
    46441 aactgctata ccagttatat caagagctgt agatataatt ggtgatgaaa ctgtagatgg
    46501 gtctgcatcc atttttttta ataaaacagg cataaacgca cctattgttg cacctaaaac
    46561 catatttata aataatgata ttgaaacaat taatacaatg tctaactttc tcataacaaa
    46621 gtaaattaca atacctgtta ttatactaca caaaagacct gtaataatac ctacaatacc
    46681 ttctctaacc acattgctaa aatttaaatc cttattagat aatgttatta ctgtaacaga
    46741 tgatgattga gttccaatat ttccacccat accaattact acaggtataa aaaatactaa
    46801 tggagcatat acaggattca ttatatagtc taagttagaa agtattaacg aagccaacaa
    46861 ccctccaact aaggtaataa ttaaccaagg taatcgtcct ctaagtgctg atattatttg
    46921 ctctctcaat gtagggtttt ctttttcagc aacttctctt tcatgttctg aacttcctgc
    46981 aaatttatac atatcttcag ttgcttcttc ttccattaca tcaattatat catctactgt
    47041 tattattcct tttaattttt cttgtctgtc tactactgga attgctatta aattgtattt
    47101 agatactaat cttactgctt cttctctatc ttcatctaca taaacagaga ttatattttc
    47161 actcatcaaa tcttctacta tatttgcgtc tctagctatt attaattctc ttaatgacaa
    47221 tactccaact agtttttctt catcatcaac cacatatata taataaatag tttcagcttc
    47281 ttcagcttct tctctcatat ggtctatagc ctcaagagct gtcatatctt tatttataga
    47341 aatatatcca gtggtcattg ttccaccagc agaatcttca tcatagaata gtaactcttt
    47401 tacataatcg gcattctctt gattcaaaag atttattatg tgttctcttt cttcttcttc
    47461 aagttcactc aacttgtctg ccatatctcc aagagacata agttcaagta tatttttcga
    47521 gtgttctaca tccagtttag ataaaatact aataaaaaac tctacactac cttcttctaa
    47581 tatagaagat gccatatcta aaggaagtac ttcaaataat tgaattttca tgtcttcctc
    47641 taaattttcc attatatcga atatatcaat tatatgatat tcctctatta attctcttaa
    47701 ctccaatact ttattattat caattaatga ttttacttca tataataaat cttgggaagc
    47761 atccagtttc ctatccatat aacccacctt tatttatcat tatatccaaa attatttata
    47821 taattttgta aatttctcca attttctttg actttaaccc ataattgaag atttatttgt
    47881 gaacctaaaa gcaattctat atcttgtctt gctgacttac ctattccttt tagtttccta
    47941 ccattttttc ctattattat tcccttatgt gaatctcttt cacagtatat tacagcagat
    48001 acatctacta tttccttatc atttctcgct ttcatttttt caatttcaac agctacacca
    48061 tgaggtattt catcattaag atagtgaaga actttttctc ttataagttc tgctattaat
    48121 actctttctg gctggtctgt aatcatataa tctggaaaat actttggccc ttcttctaaa
    48181 taattttgta taacttttat taaggtatcc gtattctttc cttttaatgc tgatattggt
    48241 actatttctt taaaaatgcc ttctctatca tacattttga ttatatcaaa tagctcatct
    48301 ttttggtcta gttggtctat tttgtttaca actaaaatta ttggtgtctt aacacttctt
    48361 aaatcctcta ttatctttct atctccagga cctatttttt tagaatcatc aactacaaat
    48421 aatattaaat ctacattttt aaaagcttct gttgctgcct ttaccataaa ttcacctaat
    48481 ttattttttg gtttgtgaat acctggtgta tctaagaata ctatctgcat ttcttcatct
    48541 gtatatactg cttgtattgt atttcttgta gtttgaggct tatcactcat tatagctatt
    48601 ttttctccaa ctacattatt cattaaagta gattttccta catttggtct acccactata
    48661 ctgacaaaac ctgatttgaa cattaactgt ctcctaactt tttatcttct tgttttaatt
    48721 acttaaattt atttatactt ttaaatttat tttaaatcat ttccagagaa atagtttggc
    48781 aacaaatcct ttatactatg ctcaaacacc tctcctttag tatatcccgt tattattttt
    48841 atatcagaac caaactctat aattacctgc ctgcatattc cacatggata tgtttgctca
    48901 ttattttctg agttatcact tgctatagct attttataga tatccttatc accctctgat
    48961 attgctttaa aaatagctgt tctttctgca caatttgttc cacctaatga tgcacattct
    49021 atattacatc cagtataaac tttaccactc ttagttaaaa gagctgcacc tactctaaaa
    49081 cctgagtaag gagcataaga atgttgtctg gcatcttctg ccaaccttaa caattctatg
    49141 ttatccacaa caactcctcc tgtatacaat aattaaaagt tatttttatt taatactcta
    49201 cattatatca taaaaattta attagcacag atttgtttta ttttaaatat tttatgtaca
    49261 tttattttaa ttatagaaca ttccaagctg aaatactaat atagctatca acacacctaa
    49321 caaagctcca gcaatagtct cccaaaaggt atgtattttt ccttcaattc tactttgggc
    49381 aactaataca gccattatat atgcaagagt agaggcaaca actctttcag tcataagtgt
    49441 aattgcagtt gctatagcaa atgctaaggc agcatgacca cttggcattc ctccttttag
    49501 aggagtacct gtagaagtca atgcttttac aactacaaca gctataagaa ccaataatat
    49561 acatatcaag gttatatgta attctgattc tcttatttta taaattaata ttccagatat
    49621 atctgtcaat ttatcataaa acaaaatata tccaactact actgaattta gtgctgccac
    49681 tagaacgcct ccagctgcaa catcttttgc tatcttagca agaacatgat attcatcagt
    49741 tactaaatca acagcttttt ctatagctgt attaaacatt tcagcaacta caactaagca
    49801 tatggacata agtaacatta tcatttctaa ttttgaaaag ttaaaaaaca aacttattat
    49861 aagaacagca actgaaccta aataatgtat tttcatattt ctttcaaatt taaatgtata
    49921 caatatccct tctatagctg cattaaatgc tttaattata ccttgacgag ttttttctgg
    49981 tttcataaaa actactccct tgttatgttt aacttattta atatgtgttc ttctttttct
    50041 ctcatttctt ttgtattttc atctgtatcg tggtcataac ctaaaagatg aaacatacta
    50101 tgacatatta aaaaacatac ttctctttca aagctatggt tatactctat actctgttct
    50161 aaggctcttt caagagatac tactatgtca cctagggatt cttcttctaa ctcaacatcc
    50221 tcaaaatcat cacttaaaag aggaaatgat aaaacatcag tcactctatc aactcctcta
    50281 tattctctat ttaattcatg aatctcttta ttatctacaa aagaaagact cacttcataa
    50341 ttatcatcat atccttcata atctaaacat tctatgatta tatcctttat cttttcaatt
    50401 aactcctcac ttacttctaa tttatcttgt ctatcatcta gtatcaaatc cattcactac
    50461 acctactttt tattcattaa taatgctata tatctatatt actacacttt tactttcttt
    50521 tgaaagtctt ttcctgcatt ttcgcttttt tacgttcttc ttttttaaat tcttctcttt
    50581 tgtcgtgctt ctcataagct cttattattc tttgtaccaa ctcatgtctt acaacatctc
    50641 tatctgttag cattatagac ccaatacctg gaacaccttt aagaatctct gtagcttgta
    50701 ttagaccact cttcttattt tgtggtaaat ctgtttgagt tacatctcct gtaactacag
    50761 ctttagagcc aaatccaagt ctagttaaaa acattttcat ttgttcagaa gtagtatttt
    50821 gagcttcatc caatattata aatgaattat caagtgttct acctctcata aatgcaagtg
    50881 gtgcaacctc aatagtacct ctttctaaat acttattaaa tttatcagca cccaacattt
    50941 caaataaggc atcatatagt ggtcttaaat atgggtcaac tttgtccttt aaatctcctg
    51001 gtaaaaaacc tagactctct cctgcttcca cagctggtct tgtaagtata attctactaa
    51061 cttcatctct tttaaaagct tttactgcca tagcaaccgc aagataagtc tttcctgttc
    51121 cagcaggtcc aacaccaaaa gttatatcat tattttctat aagttttata tattcttttt
    51181 gacctaaagt tttaggttga acagcttttc ccctttgagt tatgacgatt gtcccctcaa
    51241 gttcttttat tttttgttca cttccttcaa gcaaaagaga taatgaataa gaaatactct
    51301 gcttatctaa atgcttacca tttgatacag tttggtgtaa ttcattcata agttttaatg
    51361 cagaatctac atttttttct tctccaatta aaattatatt gccttctcta agtattacat
    51421 ctatatttaa agtcttctct attaatttta cattttcatc aaagttgcca aataactctc
    51481 tttcaaagtt accatctgct attgtaaatt tcttttgtat tatcaattga attagtcctc
    51541 ctaagatttt aagtttaatt ttattagttg ttattgctat tattattttg actattatta
    51601 ctattttgat tactattatt ttcatcagaa ttgttttgat ctttattatc cttattatcc
    51661 tcatcaaact catttcttat atcatttaat ggtctttttt ctggattgga aggaacttcc
    51721 tcttcacctt catctggttt actttcttcc tttataaacc tttctgcttc tgacttacta
    51781 agaggataaa ttttagcaat attttcacta gtttgaactg ttattaaata ttctaacata
    51841 tttttattaa ccttaaagtt atgttttaca tctattattc tagccgaagc tgggattatg
    51901 tattctaact cttttaaagc tttttcagat aattcttttt ttaactcttc tttattcctt
    51961 tttacttcaa ccttttttgt ttcataaaaa gtactcgttt ttatctttat tggaaaagta
    52021 tagtttccta ttgatagttt tttttcttta ttttcaacaa cataatcttt atattttata
    52081 ttttttctca ttgtaaactc tttatcataa aaacttagtg tatatatatt tttcttttct
    52141 ccagtttttt tatttacagt atctacataa cttgcctttt ttgtggactc ataaaaagta
    52201 cttgcccata cttctggtat tgacttggta ttagctccat ttaataagac atctcccttt
    52261 tggactatgt ctccagattt aataactgat ttaccacttc tagggattac cttttctatt
    52321 ataccatttt ttaaagcaat tacattacaa taatttgatt ggtctgtaga ttttagggat
    52381 tctgcctttt ttgtaacagt aacaaatata tttgttcctt ttacattgat agataaatat
    52441 gccacatcat taaattttga catcatatgg tctctaactt cttttctatc aatactcttc
    52501 ttatagactc ctggtcttac tccaacctta taaagctcat ttctaagagc ttcttttttt
    52561 ataccttcag gagattgtat atatacatct gtcacaaact gtgatgtaga catcaataaa
    52621 aataaagaaa caagagcaca aatccacata cctttgtgct tataaactct tttgataata
    52681 aaagggaccc cagttttttg ctttaccttt atatcaaact tacttcctct ataaacattc
    52741 ttaaattctt ttatatcttg tctatctata tgaaactcca ttttagtatt ttttattcta
    52801 gttacattgt aaacacttat cccatttctt ataagatgat ttaaaaattg ttcgagtcct
    52861 actccttcca caactataac atagtatccc cttataaaac ttatcaagtg tatctcctcc
    52921 taatcaacat actcaacatt gtagataatc ccttttatac ctatctcact atcagtaata
    52981 tacttaagtg aaagtttatc cccagatatt ttaattgttt taactttagt ctttattctt
    53041 attaaatcaa cttcatattc taatattgat agataatttt ctatactaat aaacgtatta
    53101 cttgtaacag taataactgg ttgatttact tgtaaatcag tggatatttc taacataagc
    53161 attaccccct taattaattt tatgcttgaa ataggtattt atgcacttta ttgatgttgt
    53221 aacagattag ttttaaaatt tttatataat aaatacctaa tatctaatat attatttaaa
    53281 caagaaaaag gtaatcatat tgataaaaaa tcaacatgat taccttttta ttttttctta
    53341 tataaaatct aaacgtatac aatttttatt aatcttgttc tattaaacca tatccaccag
    53401 ctttacgctt atacactatg tttatttcaa aattatcttg gtttctaaac atatagaaat
    53461 tgtgtcctac tagttccatt tgaagtatcg cctcctcaga actcataggt tttacattaa
    53521 atttctttct tctttctatt actatattct catcttcttc atcatcataa tcataatcat
    53581 caaattcact gctattatct ataaagtcaa gattttcaaa tcttatgctc ttattatttt
    53641 gaactttgtc tttaacttta gttttatatt tgacaacttg tctacttaat ttgtcacaaa
    53701 caatatcaat tgctgcatat aagtcatctt ctacgtcttc tgctcttatt atttgaccgt
    53761 taataggaat tattgtaacc tccacttttt gtctatcctt tttcgcactt actgttactt
    53821 tcacttctga ttcaggatca aggtattttt ctaacctact taattttcca tctacgtatc
    53881 cttttattcc gtcagttaat ttcatttgtc tcccagatac tattatttgc ataaaaacct
    53941 ctcccttcaa gcctttccaa ttctaatact ttaatatgtt aatctttaaa tacaattttt
    54001 ataaatttat tgtatttaaa ttaatattat tgtatatgaa aatgattatt tttaatagtc
    54061 tatttatttt tcgtttgtta tgatattatt aaaagtacag ggtaatttac aaaatcttta
    54121 cattctattt attaataaac catataaaat agttcaaaaa tcctgcataa acaagccaca
    54181 ttaaataaat caaatttatg tatccagatc tcttatctat tttagaaaac ttcgaaatca
    54241 ttattataga aaccaaaatc attattatta tatctatcaa agctgtaaat ctaagtccaa
    54301 atccaaaaaa tagtatactc caaataaagt ttaatacaag ttgtaatcca taataaaaaa
    54361 ttgcatctct tactttaggt aagttgtaac cctttcttaa tattaggtat gaagatatac
    54421 ccatcaatat gtacaatata gtccaaacta taggaaagat aaaagctggt ggtgcaaagc
    54481 ttggctttgt gagttgtaaa taataggttg aaatatctgt tccactgata atcattgtta
    54541 agatgctact taagtaacct attattagtg gtataaatat gtttatcaaa aaattcctaa
    54601 tctcttttac tgatataatc aaatttttcc ccttctttca aaattttctt tgattataga
    54661 tatgctcaaa tatgactcgt tattcccaaa aactataaaa agcctagaga tttctctcta
    54721 ggctatatca atctattgta agttttgttt taccaactta tttataagtt ttccgtcagc
    54781 tcttccttta acttttggtt ggataactga cattattttt cccatatcct tcatagaagt
    54841 tgcccctact tcagatatag tagattttac aatttcttct aactcttctt cgcttaattg
    54901 ttgaggtagg tactctttta aaacttcaat ttcaccttct gtttctttta ttaagtcttc
    54961 tcttccagct ttttcaaatt caactaatgc atctctacgt tgctttaatt gttttgctat
    55021 tacatcgata attccatctt catcaagctc gaccctatta tcaacctcat actgctttat
    55081 agaagctctt attaaagtta ctacagattt tctcactgta tctttgtttt tcatcgaaga
    55141 tttcaaatcc tcttgtaact tttgcttaag ggacatcccc ttcacctctt tattcttatt
    55201 tactactatt tcttagcgtt ttttcttctt gctgcttcag cttttttctt acgcttaacg
    55261 cttggcttat catagtgctc tctttttctc acttctgaca tgatgccaga cattgcacat
    55321 tgacgcttga atcttcttaa agcgctgtct aatgtttcat tctctctaac tcttacttct
    55381 gacatttctt tttccctccc tccaatagcg caattatgct gggactgtaa ctatgttctt
    55441 tttgcataat atgcattaca acctaacact ttgtttatta taaactaaat ttttactttt
    55501 atcaagtatt tttatcaaga aggaactcaa tttttcaata atttagttta gttttgtccc
    55561 gcttcgtaat taggaagctt tttaccagct aaaatatgat agtgcaaatg tttaacttct
    55621 tgccctccat cacttccaca attatttatg actctgaatc cagtttggtc aaaacctttc
    55681 tctttagcta ttttattaat aacaacatga atatgtgaca caatgtccat ctctttatca
    55741 ggaatatcaa ttaaactatc ataatgtttt ttaggtacaa ctaatatatg atatggagca
    55801 actgggttca agtcattaaa agctaagact ctatcatctt cataaacttt agttgaaggt
    55861 atttctccgt tcgctatttt acaaaaaata caatccattc tttccacctc ctatcttata
    55921 aatattataa tttctacatg ttatagcaaa attccttcta catattcatc ttttacatca
    55981 tttattttca cttttaatat ctgaccttgt atatttttgt cactttcaac aacaactctt
    56041 atataatttg aagttaatcc ctcatattta ttgccttcta tattttgttc aaataaaaca
    56101 tccaactcac ggccgataaa tttagttgca aatttattaa aatttacttt acttaaattt
    56161 aaaagttgtt cacttctaaa gtgtttcatt tgagggtcaa cttgattttc catagttgca
    56221 gctggagttc cttttcttgg tgaatattta aaaatatgca tttgtgaaag ctctatttct
    56281 tttaaaaact cgtacgtttt tttaaactct tcatttgtct ctccaggaaa acctactatt
    56341 acatctgtag ttattgccac atctggcatt ttacttctca atctatctac aatagttttg
    56401 tactctaaag ttgtgtatcg tctattcatt ctttttagag tttcatcaca tccactttga
    56461 agtgataaat ggtaatgagg acaaacttta tccatcttta aaacttcatt tacaaattca
    56521 tctgtaaata aaattggttc aacagaacta agcctaattc tttctatttt ttctatctgg
    56581 tttatttgtt ttattacatc aagaagttta atatccctat cctttaaatc ttttccataa
    56641 gaggcaacat gtattcctgt taatacaacc tctttatagc cattattagc caattttttc
    56701 acttcatcga ctatactatc aatatctcta cttctaacgc gtcctcgggc ataaggaatg
    56761 atacaataag tacaaaatct gtcacatcca tcttgtattt tcataaatgc tctagtcttt
    56821 ccattagttt ggctgatttc tatttcttca aaagctttaa ctttcattat gtcatcaact
    56881 gtactaactt tcttacttga atttatcttt ttaatttctt caacaatctt tcttctatca
    56941 tttgtgccca tgactaaatt tacttcttct atatccaaaa tttcttctgg agatacctga
    57001 gaataacatc ctacaacggc tattattgca tctggattct tctttttaac tcgtcttata
    57061 tattgacgag attttctatc actcatatga gtaactgtac atgtatttat aacataaaca
    57121 tcagcatact cttcactatt gacttgttca taaccatctt tctcaaatag ttctagcata
    57181 gcttctgttt catattgatt aactttacac ccaagtgtat aaaaagctac ttttttcaat
    57241 ttatttttct cctcctaaat cacttagttc atacaaagct attgttgatg ctacaacaga
    57301 agctgtctca gttcttaata ttctaggccc caatgataca acattacaat tatttttttg
    57361 tatttgttct atttcttctt cagaaaatcc accttctgga cctataaaaa ttccaacact
    57421 atctatatta gaatcacatt tttttagtgc atgttttatt gaaactgttc tttcattttc
    57481 ataagggcaa atatttacat tatttttttt catatcttct aaagcttctt taaaacttaa
    57541 aacacctctt aattttggta tcttacctct tttgctttgc tttgctgctt cataaattat
    57601 tctttcccaa cgttcaaatt ttttatcttc ttttttgtca tcaactttaa caacacttct
    57661 cttagtttga actaatatta tttcttctac acccacttca gttaattttt gaagtatcat
    57721 ttccattttt ggagcttttg gaagtccctg gtatagcctt actttaagtt ctgattctct
    57781 atttatatca actttttcta aaatttctaa attaactata ctcttatcta tattcattat
    57841 ctcacaaata tactcattat tattcttgtc acatatttca agtttctcac ctaatttgca
    57901 tcttaaaact tttgaaatat gttttacatc ttcaccttct atagtgcaag ttttatcttg
    57961 tagatttata ttattttttt caacaaaaaa tctatccatt atacgtcacc atatccctta
    58021 ttttttaagc ttagaaacta ttgctgacca ttcacctaat ttttgaactt caactatttc
    58081 aaatccattt tcaattaagc tttctttaac ttcttctact ttatccaaaa ttatacctga
    58141 agatatgaat atagcatctt ctttcataaa gttttgaaca tcttttgcaa gtatctttat
    58201 tatatcagct attatatttg caactattac atccgcttta tcttttatta catcagttaa
    58261 attaccatgc attacagata cacttttttc aactttattt tcaagaacat tttcttttgc
    58321 aacttttaca gccacttcat ctaaatctac agctacaact tcttttgctc ctaatttagc
    58381 tgctgctatt gcaaggattc cactaccaca gccaatatca aatactttag aatctttatt
    58441 cacgtacttt tctaattctc taatgcacat actagtagtc tcatgtgtac ctgtaccaaa
    58501 tgccattcca gggtcaagct ctatgattaa atccccctct tgcatagcat aatcttccca
    58561 tgtaggcttt actactaccc tttgtcctac ttttgttggt ttgtagtatg ctttccatgc
    58621 atttgcccaa tcagcttcat ttacttggtc caatgataca cttccttcac ctatatctat
    58681 accaaaatct tttaacccta aaactttttg ctttattatt tcgacaaatt ccatcacatt
    58741 tttttcttca gaaacataag tttttataag aacatcatct tcttcattct ttttaaatac
    58801 ttcttcttca acataatccc agtctagttc atttttcttt tggaataaaa agtcttttgg
    58861 gtcttctatt acagctcctc cagctccttg ttcatatagt atattcgtta taggttcaac
    58921 tgcttctgtt gttgttttta tagttacttc tatccaatta ttcataagtt tacctctctt
    58981 ctctatagta atattcctgt ttttccataa cttttattat atcataaata taatattttg
    59041 ttgttttata ttattggttt taaattcaag ctaataatat ccttatataa tagtcagaat
    59101 atttaaaaat ccgattagtt aattttaaac ctaataataa aacttctatt atatctacta
    59161 tatcaatatt tgaaatccac ttagttaatc ttaaacatac aaaatctcca acttataatt
    59221 attttcgcga tgtacctgaa acccacttag ttaatcttaa acctcaaatt tattatctat
    59281 atacacttgt aaacactcta tctcacaact tatttttcct tttaaaaaaa tagtttttac
    59341 agtgagctta cagtagtact ttttgtattt tcaatgtcta aaggtatatt atatttaaac
    59401 atatgctcac ttcaaaatta agcctacagt actattatac tcaaacttac tactagattt
    59461 tagtaccatg tatccttcta ctttgcttat taacccataa taatataatc tattaaatat
    59521 aaaccctgat acttgaatcg aatcttgttg taactctcta tcttccttat aaaaatcttc
    59581 ttccagaata attttgtaac taacatcaac atctctaaaa attttagctg cttccttctt
    59641 actatcaaca atatttttgt aaggttcaaa attaaaaatt aaatccaatc catcaaaaat
    59701 ttctttattt ataccataaa tattcttaat ttctttatca caacttataa aattctcttc
    59761 aaaatatttt ttgactacac tattatcata gtaatcatcc aaaatagttt ttctaattcc
    59821 cattgtaaaa atagagttag tttttaatat gtcctttaag atgtttttag ttgtgttctt
    59881 aagtttgtta tcataaattt tatcttcact aggtagaata taaaagtttc catattcata
    59941 tttattattt ctattacatc tacccattct ttgtatcaag ctatccatag ttgctaaatc
    60001 acttattatt atattgaaat ccaaatccaa ggatatttct actgattgag ttgatatcca
    60061 aatatcaccc tctccattta atattttact atatttctct tttttatctt tgaacttaaa
    60121 tctactatgt aaaacatcta tatctacacc accatactta tcagataaat tttcttttaa
    60181 aaactcatat gttctattga ctgaatcaat agtattcttt attataagaa ttttttgttt
    60241 attttctaaa gcatcttcaa ctattgactt gatttctttt tcctttataa aagaaacctt
    60301 tacatcttta ccttcacaaa tctcttcttc cttgttgctc tcaataaaaa ctatttctcc
    60361 tttatcagta acattttcat tactttcttc ttgaaaaata attcccttgt ttatcatttg
    60421 ctctttatat gattttggaa gtgtagctgt cattaagtga aaatcaacat ctaagtactt
    60481 gcatgcaaac tgcataaaat atatcaaaat caaaaacatc tttggttcca ataaatgtac
    60541 ttcatcaaca gttatagatg cattttttac ggctgcgaat attttttcat atcccggaaa
    60601 tttaaacata ctaagtaata actggtcaac tgttgcaatt acacaaggtt tacaaaagtt
    60661 tatactcaaa tctatatccc ttaatgtcaa tacaaaatca tgttctccat tatcttcatt
    60721 ctctgaatat aagtttatat ctccatgaag taatccaatg taatcattac tacttcttgt
    60781 atctaaatca tttttatttt gaaaaatatt ttttctataa aaactttctg ctgatatttt
    60841 atttggcact aaaaagaatt ttcttttaaa agtctttcta taatctgcag ctgtttttcc
    60901 tgaacctgta aatgcaacag tcagaacatt tcttccagaa agttctctca accttttttg
    60961 tatagtattg aactctatat tatttttttc caaattaccc tgactcttat atatctcatt
    61021 taaaatcata ttatcaattt cttcatcagt aaaatcgtta taaaatttta tacctttctg
    61081 tctacttgat gcactatggt ctattaagtt cagcatccct ttatataaaa tatacttaaa
    61141 ctttctataa tttaaaactg aatcatctat ttgaccattg ttataatcac tgtctataaa
    61201 catactttca cttaatttat ctatgtaatc ataatccaat acatcttcac caaatttaaa
    61261 gtctacattt aaaatgctat ttatataact ttctatatct ttcagattaa actcttcttt
    61321 ttctaaaatg cctttttcaa tatactcata aatttcttct tgaactttac taatacttaa
    61381 cctcatataa tcttcatagt ttccatgatg taacattata cttttatata tatataactt
    61441 atcttcttct gacaagttca ttttttctaa tatatctttt aaaaatgctc cagaaaatat
    61501 attatgtctt gctatctttt ttaaagattt tttgtcagac tctaactttt tcctctcttc
    61561 ttctgagcaa ctatacgata ttttattatt aatctccatt ttttgttgca taattgaatt
    61621 aatttttcct aaatcgtgca aagcacaaca tatttttagt atctctacat ctttatctga
    61681 atatagattt agttctaata tagattctaa tacttcaaat aaatccttaa tatgttcaac
    61741 taatgtttgc tcttgttgat tagttcttaa attatatgac ttagctaata tttctttttg
    61801 catgatattt ttcatgataa acacctatct ttcaaaataa tttaaagcca tgtaaaaact
    61861 tcttttgtat caatacatac atttacctta atatttttag gatatatacc atcattatca
    61921 acatatatat aatggcaaaa ctcataaact ctatcatctc tatttgcttc taaatcttta
    61981 tatttataag gtaatgcaat caatacacct tgatttatta tagtctcgac attctcttta
    62041 tctcttaagt caactcttac atatgtattc tttaatttta tattttcttt tatagcatca
    62101 cgagtattca taggtataac ctcttttaac tcaacttctt tcacaaaaca ccctttttca
    62161 cttggtatta caaaatcttc ttttcttcct aaatttgcat atttacatgg actttcaagc
    62221 ttttttctaa taaattcaag ttcttcatca tccttgcaag aaataaatat agtcagttct
    62281 acttctttaa gaacttcata gtttaatatg ctattttgag ctttatgttc tttatagtaa
    62341 tcatagtagt ttccttgaag caaaaacttt tctttatctt tgccttttct catatttgta
    62401 tattcattcc aaaaatcaat gttctctcct cttgaaaatt ctagttctct atgatgatgt
    62461 gttccaatta ttcctatatc tatatcagag tttaatcttc tatcacataa atacgttatc
    62521 attcccatta ttgtggtctt agatggtaaa tttaaagtac ttatatattc attttgaaat
    62581 acttttgggt ctctatagtg agcagttggt tgcttaagtt tacattgtaa tactttcata
    62641 attcaaaaaa cctcctactc ttttaaatac cacatattat cttctccaat ttccaatcta
    62701 tctgctagat ttttaatctc ttttacaggg tatttactta aattaaactt atttaattcc
    62761 tttttattag aaatttttaa tctgtcattg atagcaagta ttgtgttact ttctttaagg
    62821 ctataacttt ctatagtttc tatgactccc tctaaattta tctcaccact atcagcatta
    62881 taatctacat catcccaaaa aaatggtaca actttatcaa aagctccacc cattactgca
    62941 agtggtttta atagtactga tgaatgtttt atgtttcttg taaacacagt aattgcatct
    63001 aatatatctt ttactgcttt ttctcttaac tccttactca taaattttct ttcttctggt
    63061 aaaagtaact ttccatcttc ttctacttct actactccta ttctatcaag ctccaatgtt
    63121 attgtataaa cgtagtaatc tgataaagtc tcttctattg ctaatgcttg tgttgttgga
    63181 aagttttcat ctctaagtac ttcattttct tccctctcat cataatattt tctaccaaat
    63241 tcgctactta aaaaacctct atttgttatc aactgtgttg aacctctata tgaatttagt
    63301 gacctaaaag gtattattct aagcggagaa gccttactta tagaaccttt ctctttaagt
    63361 ggtattaaat aaccaaatac atcagtctct aatccatttt catctacaca tcctacattt
    63421 ttcttaatag atggatatat atttcctttt tttccaaaaa caatattact taaattccaa
    63481 ccatattctt gatggagtat tcttcttaaa tcatatgtta ttgtagctat actagttttt
    63541 gcatgtactt tatctctata ttgttctttt tttattggtg tataatttcc atacccttgg
    63601 tcatacgaaa gtggaactgg gctttctgtc agtatagtta atgttactcc ttttactctt
    63661 ttttcattca ttttaaattt tccccctttt ttatttcatg atttcttgaa taaatagacc
    63721 tacattcgta tttaattcta attcagaact ctgcattaga ccttctacaa acccttctcc
    63781 tattaagatt ccattagaaa ctaacacatg cattatagtt tgaaatagct gagttctatc
    63841 attagactta agtagttgaa tcactttcat agaaaaattt tttcttctgg attcatctgt
    63901 cattttatta aataagtctt tacctactct tgaatatatt aaattacttt ctatatagtt
    63961 tttcatttta tactcctccc ttccatctac aatccaacac aattttatat ataaaccgat
    64021 attatatgaa ctagatacaa aatccatttc tcgagaagtt ccagttagtt gccttaaaac
    64081 acttatatta tcaagtaata attcttttaa atttgataaa ttcccattat taatcatttt
    64141 tttacccaaa tttctagtat tcattggctc tcttgaaaaa ttataattat ctataatatc
    64201 tataagttca atttttttta ataattcttt atactctata atagagtcaa attttagaat
    64261 tataccttta ttcgtatcaa tatcaatcct atatagtcta attgaactta ttttttcatg
    64321 caaaagtttt ttataaaatg atttatctga atacattttt cttttaagca ttatcttatg
    64381 atttaaaaat gctaattctc ttaaatcatt cgtatatgca aaaaccattg gtctttttaa
    64441 atttatatat aaaagacaca ttaagttgaa aaattcacac tcaaaacaaa tattactttc
    64501 aacttgtcca cttcttttaa aacctgattt ttctgcacct ctaaataaaa agttatactt
    64561 agagtccttt cgttctctta aatcaatatc tagttttgtt gttttattta tattgcaaac
    64621 attacataca ctatcttttt cttcatattg tttcaaatca agtttatcta tttcatctat
    64681 ctctatattt gatttaatca caatatcgac tattcttttt acattttttt ccatattttc
    64741 tagactcgtg tttaatccat acttaccact atttctaaca tatggaaatc ttctgttttt
    64801 aaaatctttt ttaatccctt ccttttgttt ctcagttgca gaagatttat ccaattcttc
    64861 aataaaattt acatatgtta aattatctat attactaaat attttttcta aggtttcctt
    64921 tttcccattt ttaaatacct taaaaagttg attttctaat atataatcag atatatactt
    64981 agggtctata tattctgcag attctaaaga taaataattt ctattcaact cacaagtaaa
    65041 ttttagctta taatcatttt tttctagttc gttttttaaa tccattagta attcacaaaa
    65101 gtaaacaatg ccaatatctc ttacaatatc acctgatcta taaaatttag cttttatttc
    65161 tctcacctcg ctactttaat atatcaacca ttcctgcatt ttccgtcctt ctatatccaa
    65221 ttcccatttt atacagtgca tttaaatctt ccatatttcc ttttaaaaaa aatgttcctg
    65281 cataagcatt tatatagtaa aattctctct ctttaaatcc acgaatcttt tcttttaaca
    65341 ctcttttttt gaagttaaga ggtataaatt ccaatggctt tctaagccca ctacctctta
    65401 tactctccag agttagatta gctatatagt ttaaacattc tatataattt gaatcttcta
    65461 catctaaata tttaccttct ttattcttta ctattatagg agacatagtt ttaaatataa
    65521 caccattttc ttttatctcg tgttctttat gtatttttat attttttatt ttaaatctat
    65581 aacctttata ttctagctcc tttactttta aaattccatt gtataattta ctgaacatag
    65641 aataattata aaaacttata ttgaatatta tatctcc
//
LOCUS       DAEPHU010000014        62866 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 01A10CD0081
            SAMN05941466-rid12468953.denovo.014, whole genome shotgun sequence.
ACCESSION   DAEPHU010000014 DAEPHU010000000
VERSION     DAEPHU010000014.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941466
            Sequence Read Archive: SRR6291087
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 62866)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 62866)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068158.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 22:43:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,892
            CDSs (total)                      :: 3,805
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 87
            rRNAs                             :: 8, 1, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 55
            CDSs (without protein)            :: 55
            Pseudo Genes (ambiguous residues) :: 0 of 55
            Pseudo Genes (frameshifted)       :: 21 of 55
            Pseudo Genes (incomplete)         :: 28 of 55
            Pseudo Genes (internal stop)      :: 16 of 55
            Pseudo Genes (multiple problems)  :: 8 of 55
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..62866
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941466-rid12468953.denovo.014"
                     /strain="01A10CD0081"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            complement(178..957)
                     /gene="hisJ"
                     /locus_tag="KR231_000964"
     CDS             complement(178..957)
                     /gene="hisJ"
                     /locus_tag="KR231_000964"
                     /EC_number="3.1.3.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidinol-phosphatase HisJ"
                     /protein_id="HBH0003369.1"
                     /translation="MKDGHIHSPYCPHGSKDDFEKYVQRAMDVGITEMTFTEHFPYAN
                     GFRDPAPENDSCMSIEDLPKYFNDVKKLKEKYEGKIKINVGSEVDFIEGYEEGIKENL
                     NKYGKELEDSLLSVHIIKIDDDYYCVDYSVEEFQNLIDKLGSIEAVYNKYYETLIKAV
                     NSDLGIHKPKRIGHLNLVRKFNQVFPYDYKGNTILEELIKLIKEKGYELDYNVSGNRK
                     EYCKEPYIDGYLLELVKKYDIPLILGSDSHCAEEINKYDIV"
     gene            complement(1503..1853)
                     /locus_tag="KR231_000965"
     CDS             complement(1503..1853)
                     /locus_tag="KR231_000965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc transporter"
                     /protein_id="HBH0003370.1"
                     /translation="MIFDKEIVRYHHGHHDHDHCHEHTHGDICHEHPHDHAHDHDHEH
                     SHEESSESKDEKTLKILLVHWINHNETHEEGFREWVEKARAIGKEETAKSIEKAIEYM
                     EEANKMLLEAKKHM"
     gene            complement(1869..2285)
                     /locus_tag="KR231_000966"
     CDS             complement(1869..2285)
                     /locus_tag="KR231_000966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3842 family protein"
                     /protein_id="HBH0003371.1"
                     /translation="MIIAVIDGMGGGIGAQIVSSLREELPTYVEIYALGTNSIATSSM
                     MKAHANKGATGENAIVVSAKKANIIVAPISVIIPNSMMGEVTCNISEAIADSEALKIL
                     LPIMPENVELVGLEGKPLALLVKDSVNLIKKEFNIK"
     gene            complement(2304..2495)
                     /locus_tag="KR231_000967"
     CDS             complement(2304..2495)
                     /locus_tag="KR231_000967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CooT family nickel-binding protein"
                     /protein_id="HBH0003372.1"
                     /translation="MCESSAFICKSNNELEKVMENVVNIDPCDGKIYLTDLLGEQKII
                     DGIIKEIRLMDHKIIIQEN"
     gene            complement(2646..3461)
                     /locus_tag="KR231_000968"
     CDS             complement(2646..3461)
                     /locus_tag="KR231_000968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate--protein ligase family protein"
                     /protein_id="HBH0003373.1"
                     /translation="MNQWRVIHNKSYEGAMNMAIDEAIFTAYKKGHNKPTLRFYTWEP
                     ACLSIGYFQKLEDEIDLDKCRCMNIDYTRRITGGRAVLHDNELTYSIIIGEDNPLIDK
                     SINLSYRYISEGLVKGLNLSGIETDNLNRGERISRENLSAACFNAHASYEVTINNKKV
                     IGSAQSRKDGVLLQHGSIILDFDVEKLFKLIKTKTPELKERAMKFTAKKASGIENEIG
                     RKIDIDILQKNIVKGLAEQFNVEFVEGDLTDYEKQLVKELYEKYKNEEYNKKR"
     gene            complement(3508..4446)
                     /locus_tag="KR231_000969"
     CDS             complement(3508..4446)
                     /locus_tag="KR231_000969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM protein"
                     /protein_id="HBH0003374.1"
                     /translation="MIRLSVGTAIELGILNKKSDIPPTTAYIMIGEKCINKCSFCSQS
                     IESSTRKDKLSRVIWPEFSKEEILDALKAYKGKNIKRICIQSMASEEAHNSVLDFINY
                     ISGKIDMPISLSAKLENDEQIKKFFSVGVDKIGIAIDAANKELYEKIKGNNYDEKLKF
                     ITEMSKSYPNKISTHIIVGMGESHEDIYNLYTYLKENDVTISLFAFTPVRGTKMEKIN
                     QPSIESYRRVQLMSYMINKGYPKEYFKFKNGYLNSIKLDNDILKDINKGYPFEIRGCK
                     DCNRPYYNERPGSTIYNYSRPLNQSEIDLAIREINL"
     gene            complement(4443..5315)
                     /locus_tag="KR231_000970"
     CDS             complement(4443..5315)
                     /locus_tag="KR231_000970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM protein"
                     /protein_id="HBH0003375.1"
                     /translation="MNKNLSEKMEIAFDIKLKNFGNKIEFAYPNQTLALSTTSNQCSL
                     KCAHCNGHYLNNMVPIEEYEEKVQSRNITSFLLSGGCSYEGDVPINTHINTIKNLKEQ
                     GYRLNAHLGLMDKDSIVELCKYLDIVSFDLVFDDETIREVYKMKKSKEDYIEVYNTIQ
                     EHTEVAPHICIGLKGGQIKGEYEIIEYLQKNPPNKLTFIVLIPTKGTEYENVEPPELE
                     GVADILCEARINLPDTEINLGCMRPRGVYRKELDQLSIMCGVNRIVLPSRSAKNKAIE
                     MNMTINECKECCVL"
     gene            complement(5340..7268)
                     /locus_tag="KR231_000971"
     CDS             complement(5340..7268)
                     /locus_tag="KR231_000971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4445 domain-containing protein"
                     /protein_id="HBH0003376.1"
                     /translation="MIKVSFTPNNKEVYCNEGDILLEVARNADIFIDAPCNGNVSCGK
                     CKVKLLNGKVDTEKTRHITDDEWEQGYILACCTKVISDIEIEVPSKVSSSMHGMKIEG
                     SNKKEDREIFERAKKIIEEHNLQFKTNIKKKYIEMEEPNLDDNISDVDRLERYVRNNL
                     GYNEIDFRLDILRKMPTVFRKSDFKVTITYVQKQKKLTIINIEQGNKENSLYGVAIDI
                     GTTSVVVCLVDLYSKEVVDKASSGNAQIKYGADVINRIIYSTKKNGLETLHKAIVEET
                     INPLLKTIYERNGIDKEDVVTLVAAGNTTMTSLFLGVYTDFLRQEPYIPPFLKSPKLM
                     GENVGLFVNDSAYVYLAPSVASYVGGDITAGVLSAGIWSSEENVLFIDLGTNGEIVFG
                     NKDYMMSCACSAGPAFEGGGISCGMRASAGAIEKVIIDKETLEPTLKIIDECAPVGIC
                     GSGIIDLICQMITKGVIDRRGKIYRDLDNKRVRFNEHEIGEYVLAFKEEFDLENDIVV
                     NEVDIDNFIRAKGAIYSGAYTLVDSLGMDFSILDRVYIAGGIGNNLDIENSIIIGLLP
                     DIDREKFTYIGNSSLVGSYLALISKDAKNKLEEIGNQITYVELSVYPSYMDEFISACF
                     LPHTNIEQFPTAKKLLEE"
     gene            complement(7380..7757)
                     /gene="gcvH"
                     /locus_tag="KR231_000972"
     CDS             complement(7380..7757)
                     /gene="gcvH"
                     /locus_tag="KR231_000972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine cleavage system protein GcvH"
                     /protein_id="HBH0003377.1"
                     /translation="MKLLPELKYSKDHEWVKVIDGDVVYIGITDYAQDQLGEILFVET
                     PEVEDTVTKGVDFGVVESSKVASDLISPVNGEVLEVNEKLEDEPECINEDPYENWILK
                     VKLADVAELDTLLSDKEYEAGLE"
     gene            complement(7844..9970)
                     /gene="cdhC"
                     /locus_tag="KR231_000973"
     CDS             complement(7844..9970)
                     /gene="cdhC"
                     /locus_tag="KR231_000973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CO dehydrogenase/CO-methylating acetyl-CoA
                     synthase complex subunit beta"
                     /protein_id="HBH0003378.1"
                     /translation="MNLYNIIFTGSEQALGAAQAMLAEAIEKNGKEHKVAFPDTAYSL
                     PCIYAATGQKMNTLGDLEGALEVVKSLINRTHLLEHAFNAGLATALAAEVIEALKYST
                     MDAPYSEPCAGHITDPIIRSLGVPLVTGDIPGVAVVLGECPDAESAAKVIKDYQSKGL
                     LTFLVGKVIDQAIEAGVKMGLELRVIPLGYDVTSVIHVVSVAVRAALIFGGLTPGDLN
                     GLLEYTANRVPAFVNAFGPLSELVVSAGAGAIALGFPVITDQTVLEVPMNLLTQKDYD
                     KIVATSLEARGIKIKVTEIPIPVSFAAAFEGERIRKSDMFAEFGGNRTEAWELVVKKE
                     ATEVEDHKIEIIGPNIDEVDADGVLRLPLAVIVKIAGKNMQEDFEPVLERRFHYFLNY
                     IEGVMHVGQRDMAWVRISKDAFDKGFRLEHIGEVLYAKMLDEFESVVDKCEITIITDA
                     EKVSELKGEAIAKYNARDERLASLVDESVDTFYSCNLCQSFAPAHVCVVTPERLGLCG
                     AVSWLDAKATKELDPTGPCQPIEKGECLDDRTGVWNSVNETVNQISQGAVESVTLYSI
                     LEDPMTSCGCFECICGIMPEANGFVVVNREFASVTPVGMTFGELASMTGGGVQTPGFM
                     GHGRHFISSKKFAYAEGGPERIVWMPKELKDYVADKLNATVKEMTGIENFCDMVCDET
                     IADDSEGVLAFLEEKGHPALAMESVM"
     gene            complement(10027..10833)
                     /locus_tag="KR231_000974"
     CDS             complement(10027..10833)
                     /locus_tag="KR231_000974"
                     /EC_number="2.5.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydropteroate synthase"
                     /protein_id="HBH0003379.1"
                     /translation="MEKFMIIGERIHCISPSIRKALAERDPAPILKRAKEQLEAGAHY
                     IDFNIGPAERDGEEIMTWGIKLLQSEFNNVPIALDTANKKAIEAGLKVYDRTNAKPII
                     NSADAGSRFDLIDIAAEYEAMVIGLCAKEGIPRDNDERMAYCQEILEKGLMLGMEPTD
                     ILFDPLCLVIKGMQEKQVEVLEAIKMMTEMGLLTTGGLSNVSNGCPKHVRPVLDSAFL
                     AMAMANGFSSAIMNPCDPELMKTVKSCDIINGASLYADSFLELNEGGFAF"
     gene            complement(10883..12250)
                     /locus_tag="KR231_000975"
     CDS             complement(10883..12250)
                     /locus_tag="KR231_000975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA decarbonylase/synthase complex
                     subunit gamma"
                     /protein_id="HBH0003380.1"
                     /translation="MALKALDIFKLTPKKNCKDCGFPTCMAFSMKVASGAVEVGKCPH
                     MSDDAIAKLSEATAPLMKALKVGAGASEYELGGETVLFRHEKTLVSRNRYAVSFCTCM
                     SDEAVDAKIANMKKVDYVRIGEQMKVEMAVLEYCGDKDAYLKLIDKIKGSGLEVAYIL
                     ACDDAQVVKEAVEVLKDARPMVYGATKENYKDMIEVVKGASLPLGVKAGSLEELYETV
                     ELIQAAGYKELVLDVTGENIKDTYTNAIQVRRTALKEQDRTFGYPSIVFANRLSNSNP
                     MMEVALSSIFTIKYGSIIVIDDISYAKALPLFALRQNIYTDPQRPMRVEPKIYPINNP
                     DENSPVLVTVDFALTYFIVAGDIERSKVPVWLVIPDAGGYSVLTSWAAGKFGGNSISA
                     FIKESKVEEVTNCKDLIIPGKVAVLKGDIEDNLPGWNVVIGPEESMELPKFLKGYQEK
                     ACQTN"
     gene            complement(12281..13225)
                     /locus_tag="KR231_000976"
     CDS             complement(12281..13225)
                     /locus_tag="KR231_000976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA decarbonylase/synthase complex
                     subunit delta"
                     /protein_id="HBH0003381.1"
                     /translation="MAFKMSTQKYSGKISEVEVGIGEKAIKLGGENVLPFYSFDGEVG
                     NSPKIGIQISDVYPESWTDSYKELYKDVANCPVEWAKYVEANTQADFICLKFDGSDPN
                     GLDKSVDECADVAKAVIEAIKLPLVVAGSGNHEKDGKLFEKLAQTLDGHNCLFMSAVE
                     DNYKGVGASAGMAYAHKVGAESSVDINLAKQLNVLLTQLGVKGENIVMNVGCSAVGYG
                     YEYVASTMDRIRLAAFGQNDKTLQMPIITPVAFEVGHVKEAIAPIEDEPDWGCPEERT
                     IAMEVSTAASVLVGGSNAVILRHPKSIETIKELVNALA"
     gene            complement(13245..14015)
                     /locus_tag="KR231_000977"
     CDS             complement(13245..14015)
                     /locus_tag="KR231_000977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HBH0003382.1"
                     /translation="MGYNIAVAGKGGTGKTSLTGLLIDYLVKDKKGPVLVVDADANAN
                     INEVLGIEVEATIGEIREEVNQREKLGNAFPGGMTKAQYLQFRLNSIIEEGEGYDLLV
                     MGRSEGEGCYCFVNGILREQVNKISGHYKYLVMDNEAGMEHLSRKVTRHVDTLLLVSD
                     CSRRSIQAVARIRDLAEELKLSVGRILLIVNKVPNGVMNDGVKEEIEKHNLELIGVVP
                     MDELIYEYDSTGIPLVNLPEDSKSKVAMKEIFAKLELK"
     gene            complement(14071..15456)
                     /gene="lpdA"
                     /locus_tag="KR231_000978"
     CDS             complement(14071..15456)
                     /gene="lpdA"
                     /locus_tag="KR231_000978"
                     /EC_number="1.8.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoyl dehydrogenase"
                     /protein_id="HBH0003383.1"
                     /translation="MKIVVVGGGPGGYVAAIKASMLGADVTVVEKRRVGGTCLNAGCI
                     PTKALLASSGVLNTVKEAKDFGIEIDGTVKPNFTAIMERKNKVVNQLISGIEFLFEKR
                     GVNLVNGFGKLIDKNTIEVTKDDGTVETIKADKIILANGSVPVVPRMFPYDGKVVITS
                     DEVLGLEEIPESMLIVGGGVIGCEIGQFFRALGTEVTIVEMVDQILLNEDKDVAKQLL
                     RQFKKDKIKVITGIGVQTCEVVDGKAVATLSNGKVIEAQYALVCVGRRPNLDNSGVED
                     IGIEMERGKVVVNEHLETNVEGIYAIGDIIDTPFLAHVASKEGIVAVENALGKTKVVD
                     YRAIPRCVYTEPEVAGVGKTEKQLEAEGVEYNVGQFDFRGLGKAQAIGHFQGFVKVIA
                     DKETDKIIGAAVVGPHATDLLTELSLAVHLGLTVEQVGDAIHPHPSLSEGLMEALHDV
                     HGECVHSVPKL"
     gene            complement(15500..16381)
                     /locus_tag="KR231_000979"
     CDS             complement(15500..16381)
                     /locus_tag="KR231_000979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylenetetrahydrofolate reductase"
                     /protein_id="HBH0003384.1"
                     /translation="MSLLRETLESGKFAVTTEMAPPKGTDLSHLIECAKPLVGRVHAA
                     NVTDFQSAVMRATSLATCKLLKDAGLEPVIQITGRDRNRIAIQGEMLSAGVFGINNLL
                     ALTGDHTSVGDHPQAKGVFDLDSVGILQTAETLMAGTDMAGNKLKGSPDFYLGASVTP
                     EYSPIEVQLLKMKKKIKAGAKFFQTQALYDINTMRKFRELTRDMDCKVLAGIVPLKSP
                     GMAKFMTANVPGIFVPDEQIERLRAAGKENWVSEGIKMAGELIKQLKEEDLCDGVHIM
                     AIGAEENIPAILDAAGL"
     gene            complement(16417..17091)
                     /locus_tag="KR231_000980"
     CDS             complement(16417..17091)
                     /locus_tag="KR231_000980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylenetetrahydrofolate reductase C-terminal
                     domain-containing protein"
                     /protein_id="HBH0003385.1"
                     /translation="MIISENKPLEEVLGYLKDFDKLVLVGCNQCAATCKSGGEEEVLK
                     MKETLEGEGKKILGYVMLDPACNLLKSKKDLKALKEETKEADAVLSLACGDGTQTIVK
                     NLKDKPVYPANNTLFIGEVQRVGEYEEACKACGDCELGWTGGICPVTMCAKGLMNGAC
                     GGAKNGKCEVNSENDCAWIKIYERLEAIGQLDNLAEIRPPKDYSKQNNPRSLSAKKKK
                     EAAANS"
     gene            complement(17128..18000)
                     /locus_tag="KR231_000981"
     CDS             complement(17128..18000)
                     /locus_tag="KR231_000981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional 5,10-methylene-tetrahydrofolate
                     dehydrogenase/5,10-methylene-tetrahydrofolate
                     cyclohydrolase"
                     /protein_id="HBH0003386.1"
                     /translation="MEGMSTKGQIIKGKPVADKISEELIKEVDLLIKEGINPKLTIVR
                     VGARSDDLSYERGALKRCQNIGITTEVLELAEDITQEEYIDVLKRVNDDKNVNGILCF
                     RPLPKHLNEEVIKYVIAPEKDVDCFSPINSAKVMEGDKSGFPPCTPTAVVEILKHYNV
                     DLKGSKVTVLGRSMVVGKPVSMLLLSEHATVTICHSKTKNLSGVAAEADVLIAAIGRA
                     KMVDESFVKDGAVVIDVGINVDEEGNLCGDVDTNAVLDKVSMITPVPAGVGSVTTSIL
                     AKHVVKACKLQNNK"
     gene            complement(18092..18724)
                     /locus_tag="KR231_000982"
     CDS             complement(18092..18724)
                     /locus_tag="KR231_000982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cyclodeaminase/cyclohydrolase family protein"
                     /protein_id="HBH0003387.1"
                     /translation="MKIADKTCVDFVEVLSSKEAVPGGGGAAALVGAIGMALGSMVCN
                     LTIGKKKYAEYEESVKEILSKAGKLEKDLLKMIDDDAECFLPLSKAYGLPKETEEEKR
                     IKAETMEKALKVACEVPLNIVRVCYEAIKLHEDLVDKGSRLAISDVGVGVQCLRAAIL
                     GGQLNVVININSIQDKEYVNKVKTEVDKLVEDGVKICDEVYAKVEKALGK"
     gene            complement(18829..20505)
                     /locus_tag="KR231_000983"
     CDS             complement(18829..20505)
                     /locus_tag="KR231_000983"
                     /EC_number="6.3.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014355320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate--tetrahydrofolate ligase"
                     /protein_id="HBH0003388.1"
                     /translation="MGFKSDIEIAQEAKPQDIREVAKKLGLGEDDVELYGKYKAKVDY
                     NLLKRETGKKAKLILTTAINPTPAGEGKTTTTIGVADAFAKLDKNVLVALREPSLGPV
                     FGVKGGAAGGGYAQVVPMEDINLHFTGDFHAIGAANNLLAAMLDNHIHQGNALRIDPK
                     KITWRRCVDMNDRQLRNIVDGMGKKGDGAVRQDGFDITVASEIMAAFCLASDISDLKE
                     RLGNIIVGYSYEGEPVTARQLKANGAMAALLKDALKPNLVQTLEGTPSFVHGGPFANI
                     AHGCNSVIATRMAMHFADYVITEAGFGADLGAEKFLDIKCRMANLKPDAVIIVATVRA
                     LKYNGGVAKADLNNENLEALEKGLPNLLKHVENITQVYGLPAVVAINRFPLDTEAELK
                     LVEDKCKELGVNVALSEVWAKGGEGGIAVAKEVLRLLDEEENNFRFCYEDDLSIKDKI
                     NAIATKIYGADGVDYTPEADKEIANLEKLGFTKVPVCMAKTQYSLTDDQTKLGRPTGF
                     RITVRQATISAGAGFIVALTGEIMKMPGLPKVPAAEKIDVDENGVIAGLF"
     gene            complement(20754..21533)
                     /locus_tag="KR231_000984"
     CDS             complement(20754..21533)
                     /locus_tag="KR231_000984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HBH0003389.1"
                     /translation="MKIAITGKGGVGKTTFSSMLSRMFAEDGYRVVAVDADPDANLAL
                     ALGFPKEVYESIVPISEMKKLVSDRTAASVGSFGKMFKMNPKVDDIPENFCKEYNGVR
                     LLTLGTVDSGGTGCVCPEHVLLKRLCSHLILQNKDVVVMDMEAGIEHLGRGTAQGVDA
                     FIVVVEPGERSLQTYRKVKKLGHDIGVNKVFVVGNKIRNKEDEEFIIQNLEDGESLGF
                     IYYNQDVIDSDRANQSPYDSSETTKEQIKAIKDKLMSLKDK"
     gene            complement(21843..23762)
                     /gene="cooS"
                     /locus_tag="KR231_000985"
     CDS             complement(21843..23762)
                     /gene="cooS"
                     /locus_tag="KR231_000985"
                     /EC_number="1.2.7.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic carbon-monoxide dehydrogenase
                     catalytic subunit"
                     /protein_id="HBH0003390.1"
                     /translation="MDEKMLTIDLNSQKMIAKAREEGVETMYDRKEGFKAQCGFGLQG
                     VCCRICGMGPCRISPKTPRGLCGADEHTIVGRNFARMVAGGTAAHSDHARDIAHTLAL
                     ADPNGNYKIRDEAKLITLAKEWDVETEGRDIYDVAHEVAEIALMEFGKPFGTLRFIKN
                     APEPRQKIWKEYAIEPRAIDREIATIMHSTHIGCTGDIDSLIHMSLRTSMADGWGGSM
                     IGTRLSDILFGTPVPRRTEANLAVLEENKVNIILHGHEPALSEMIVLASEEPDLVALA
                     KEVGADGINLAGMCCTGNEITMRHGVKIAGDFHQQELAIITGAVEAVIVDVQCIFPAL
                     ARVADCYHTKFVTTSPKAKITGSTYIEFREEQALDDAKAIVKEAILNFKNRDKSKVLI
                     PELKSGATVGYSVEAVVNQLDRVVNSHIDPAGTVKPLTDCLKAGVLRGAAGVVGCNNA
                     KGVSNEAHVTIMKELIKNDIIVVTTGCGASAAAKFGLMESDAAEKYAGKGLATVCKLV
                     GIPPVLHMGSCVDISRILDLVGAAANYLDMDMCDLPVVGIAPEWMSEKAVAIGCYVVA
                     SGIDTYLGIMPPIAGSSRAVDILTSELKDKVGATFTVNTNPKELAATIIEDIEKKRVH
                     FEALVEEKMAEKAEA"
     gene            complement(24369..25280)
                     /locus_tag="KR231_000986"
     CDS             complement(24369..25280)
                     /locus_tag="KR231_000986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional enoyl-CoA hydratase/phosphate
                     acetyltransferase"
                     /protein_id="HBH0003391.1"
                     /translation="MIKKLDDILEQLKGGEKIVLSVAAAHDKEVLMAIKDAVERNIIT
                     PILVGNEGKIREISKEIGFDLSGIKIVDKDDIKECAEIAVKLVSSKEADFVMKGLLDT
                     SVILKEVLNKDYGLRTDSLLSHVMVYELEKYHKLLITTDGGMNIAPDYEQKAKILKNS
                     IKAAKALGMETVKVACLAAKEKVNPKMQATVDADMLAKACKEGEFGENVIVEGPLAFD
                     LAVSKEASEIKGFKSEVSGDVDIILVPTIEVGNGIGKAFTYMADSKSAGIIMGAKAPI
                     VLVSRADSHESKLYSIAYGAIVAKNMK"
     gene            complement(25396..25974)
                     /locus_tag="KR231_000987"
     CDS             complement(25396..25974)
                     /locus_tag="KR231_000987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar O-acetyltransferase"
                     /protein_id="HBH0003392.1"
                     /translation="MNINEFLTHINQRKPVSSKSEIHEFMVKLSNEAMKITSKLNSSY
                     HEPEEVRSLFSELIGKKVDESFFMFPPFYTDCGKNITIGKNVFINSSCHFQDQGGIEI
                     GDNTQIGHNVVLATLNHGIAPEKRGTTYPSPITIGKNVWIGANVTVVPGVTIGDNAII
                     AAGAVVTKNVAENTIVGGVPAKLLRAIDEIPE"
     gene            26200..27123
                     /locus_tag="KR231_000988"
     CDS             26200..27123
                     /locus_tag="KR231_000988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HBH0003393.1"
                     /translation="MEIRVLRYFLAIAREESISGAATFLHITQPTLSRQIMELEEELG
                     VKLLVRGNRKITLTNEGRLLHKRAEEIISLVDKVELEFDNPNEIISGDIYIGSGETEA
                     MRLIARTAHHFHQKYPNVRYHLFSGNADDVTEKLDKGLLDFGILIEPANIQKYDYAQI
                     PATDVWGLLMRKDSALASQSTINPKDLCNIPLIISRQTLVDKAISKWLQGSNEKLNII
                     ATYNLVYNASLLVEEGLGYALCLDRLVNTTENSNLCFRPLSPPLEAKLNIIWKKHQIF
                     SKAAEKFLLQIQKDFSSIMLDTSKLDTPKEK"
     gene            complement(27295..28437)
                     /locus_tag="KR231_000989"
     CDS             complement(27295..28437)
                     /locus_tag="KR231_000989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418311.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HBH0003394.1"
                     /translation="MDFKIEKYLLKKAEELAFITIKHGGEFKLKSYEVPKGGLDVPIK
                     NEVLVKGIKEKTAQDKLNSMSIADAMIYIIGIDSKFKNNAEYEKFLNALSKDIDLDLK
                     SYMGYMSRKYFEIGEHTDSLIYIKAFITMYPDDLDAMYNYAIVCQEIAKQYQKDMDDK
                     AMNAFLLEAMAKLEKVIDVDENFALGYYHLGYHYYNQGQYLKTKLTWEEALRLGLDAD
                     LVAEVQENLGKMDFKVQYEEGYTLVFQGKFKEGLEKLLPLEEEHMDWWNLLFMIALGY
                     KGMGEIEQAKMYLEKILIIKPNQVDTIVELGLCEAYKNNLDKAIEYFEQAAKIKEDPE
                     ILCNLGMAYLNNGDIDDATYYIERAYELNPQDEITIACLRELGINK"
     gene            complement(28455..30209)
                     /locus_tag="KR231_000990"
     CDS             complement(28455..30209)
                     /locus_tag="KR231_000990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="B12-binding domain-containing radical SAM
                     protein"
                     /protein_id="HBH0003395.1"
                     /translation="MKILLTTLNSKFIHTNLAIRYLKEFVRDLIEVNMKEYTINNDLD
                     YILKDIYKNEYDIILFSTYIWNVGDIVKLCDNLKKIRPNTKIALGGPEVSYDSYEAMK
                     KYDFVDYILYGEGELIFRDLVLHLQGKMEINDVNGLVYRQGNEIIVNKPMELLQDLDE
                     IPSPYENLNPKEYENRIVYYESSRGCPFNCQYCLSSTIPGLRYFSLDRIKSDLKALID
                     ARVSQIKFIDRTFNANRKVAMEIMDFLMKNDNGYTTYHFEVTAYLIDDKMLEFLADCK
                     EGLFQFEIGVQSTNEKTLDAVGRRDDFKKLSHVVQTVASYRNIHQHLDLIAGLPYEDY
                     KSFENSFNDVFNLGIEHLQLGFLKMIKGTGMRKVADEHGFKYKDYAPYEFLYNNYISY
                     EETLKLKDIEDILERYYNSKNFVLSMRYIIGRFYKKSPFKFFEVFAKYFDENGYFDLA
                     QGKNQLYKILMDFYNEKINIDNDVFNDILKYDYISLGKTSNIPQFFNKLDVDDFKNRC
                     HVFLQDNDNLSTYLPSFVDKPAKHIIKYVHFEPFRFNVVDLKNDINTEIREVENVVLF
                     EYDDKKIFEKSKTHKVEI"
     gene            30345..30551
                     /locus_tag="KR231_000991"
     CDS             30345..30551
                     /locus_tag="KR231_000991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0003396.1"
                     /translation="MELIEKVSINSLSKRDLLLIIKSLEYTNENTQISDFIDLRNNIV
                     KELCFLTDTKEKDFLDYLEKNSTL"
     gene            complement(30556..31479)
                     /locus_tag="KR231_000992"
     CDS             complement(30556..31479)
                     /locus_tag="KR231_000992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0003397.1"
                     /translation="MNDELLKKVYTSSFSSASRALKDLTIINTKSLIDDKTQRCVYID
                     ENRLRDELIYYRFYGEKIGNINFLNILLPLILSNTNIQKSEDEVIKLIKKYVIYFKKE
                     ELLFDYLLGSVVYNSIMHNLINNSKIEYVELLQSIKDKIIGFSIELDKSDVVKFQMAR
                     IKAIQLIDKYIDLKSEDYDEESILLNVLNVLYDVYMEDRTVENEGINSIKKSILSILG
                     EDSKLNEDNIDFIFSMSEYVVKLRKYKIGVKAYNKSIDPRSLIRLEEGNTIVDPIFNQ
                     ITVMSKTFNDNILSIKINSKSGIYILKFKKV"
     gene            complement(31733..33433)
                     /locus_tag="KR231_000993"
     CDS             complement(31733..33433)
                     /locus_tag="KR231_000993"
                     /EC_number="6.1.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine--tRNA ligase"
                     /protein_id="HBH0003398.1"
                     /translation="MQDFKVAISNCLKEKIEDLSKEEIEALIEVPPNKDMGDYAFPCF
                     KLAKVFRKAPNMIASELAESIEPSGEITKVIQLGGYVNFFVNKSQLAETVIKKVLDEK
                     ENYGHSDFGKDKTVIVEYSSPNIAKPFHIGHIRTTVIGNALYKIYDSQGYKTIRINHL
                     GDYGTQFGKLIVAFKKWGEKEVVESNPIPELLKLYVRFHDEAEQHPEMEDEARAWFNK
                     LENGDEEAQELWQWFRNESLKEFNRVYKLLDIEFDSLAGESFYSDKMNRVIELLEEKN
                     LLKESKGARIVDLEEYKMPPALITKNDGSTLYMTRDLAAAIYRKETYDFDKCIYVVGS
                     QQNLHFQQWFKVIELMGYDWAKDLIHVGFGMVALEEGTMSTRKGRVVFLEDALNQAID
                     KTKEIILAKNPNAKNVDEISKQVGVGAVVFQELSNSRIKDYTFSWERTLSFDGETGPY
                     VQYTHARCCAVLRKAEVEVTSDIDYSLLADEDSAEVLRVIESFNKNILLALKKNEPHI
                     VTRFMLDLAQAFNKFYHDNPILVENLEIRKARLALVLATKQTLENSLKLLGMHAPERM
                     "
     gene            complement(33843..34256)
                     /locus_tag="KR231_000994"
     CDS             complement(33843..34256)
                     /locus_tag="KR231_000994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF523 domain-containing protein"
                     /protein_id="HBH0003399.1"
                     /translation="MILVSACLIGINCKYSGDNNDNEKVKEYLKGKEFTLVCPEQLGG
                     LSTPRPPAEIVDGKVITKDNKDVTENFVRGANETLKIANLYVCSEAILKEGSPSCGCN
                     LIYDGSFSGKKIPGKGITARLLEEEGIKVKSEKDL"
     gene            complement(34322..36700)
                     /locus_tag="KR231_000995"
     CDS             complement(34322..36700)
                     /locus_tag="KR231_000995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease MutS2"
                     /protein_id="HBH0003400.1"
                     /translation="MNEKSLRVLEYNKIIDLLKKKASSSLGLKYIENLVPNTDFVEVK
                     SMLEETSEAQSIIIKRGSVGLEGIHDIEDKVKRAYIGASLDPGSLIMIADTLRVARRL
                     RNSLSSSDEEDFNYPIIQSLSNSLYVYKDIEDQIYNAIISEVEISDNASSTLRDIRRR
                     IAQKNQSIRSKLNSIISSTTYQKYLQDAIISLRGDRFVVPVKSEYRSQVAGIVHDQSS
                     SGATLFIEPMTIVEMNNELRQLKLGEQEEIERILSELSAMVGEVSEDLISNQEILGRL
                     DFAFSKGKLSIQMRGIEPTLNEDKYLNIKNGRHPLLDKKKVVANTIYLGRDFHTLVIT
                     GPNTGGKTVTIKTVGLFALMTQSGLHIPADYGSSMCVYDNVFADIGDEQSIEQSLSTF
                     SSHMTNIVSILQNVTADSLVIFDELGAGTDPVEGAALAIAVLEDINSVGAKCIATTHY
                     SELKNYALTKPGVENAAVEFDIETLSPTYKLLIGVPGKSNAFEISRKLGLSDYVISRA
                     KEYINTENIALEDVLQNVEKNRIKAVEDREEAERLKEEIEKLKVEYDEKLEKLVSQRD
                     KMIEKAKSEAFSIIRQAKEEVDIIIKELRSLEQERASKEKNRKIEELRKELTSSMGSL
                     QPTVKSMIVPKVSNKEIKDLKPGEEVKVITLNQNGSVVSVDKKRKEAVVQIGIMKMTL
                     PFKSLQKTRKDVSTNVTKSTRNIIRSKSGSVKNEVDLRGLNLEEAIMEVEKYLDDAYV
                     AGLESVTVIHGIGTGVLKAGLQDILRRNRHVKSQRGGQYGEGGAGVTIVKLK"
     gene            37019..38470
                     /locus_tag="KR231_000996"
     CDS             37019..38470
                     /locus_tag="KR231_000996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-histidine dipeptidase"
                     /protein_id="HBH0003401.1"
                     /translation="MGNVLEGLKPESVFKNFEKISQIPRGSGNEKGISDFLLSFGKNL
                     GLETIQDESLNIIIRKPATKGYENCPGVVLQGHMDMVCEKEKNVEHDFLKDPIKLRID
                     GDMIYATGTTLGADNGIAVAMGMAILEDNTLEHPALEVLVTVNEEDGMNGADALDPSL
                     IKGQYILNMDSEEEGYLLVSCAGGKTCVVSLPVEYKEVKGDKQGLLVEVTGLLGGHSG
                     MEIVLQRANANKAIARVLSVLNVDYELASVDGGTKHNAIPREAKCVIAVNKADVESAK
                     KQINDILTAFKHEFTTSDPGMTYSVAETSVDKVLTKDCKEKVVQMSCLTPHGVQSVSL
                     DIEGLVESSTNFAIIETKESTIEFLTSVRSSVMSIRDEIADRIRLLAQALGANYDLIA
                     QYPAWEFKKGSKLEKICSETYEKLTGKVPTVMALHAGLECGLLLDKLPHAEAISIGPD
                     MFDVHTPNEHVSIPSVANVWDYVIEILKSMNQY"
     gene            complement(38674..41187)
                     /locus_tag="KR231_000997"
     CDS             complement(38674..41187)
                     /locus_tag="KR231_000997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HBH0003402.1"
                     /translation="MEDCVVNLKKLLLLIIVITSIFTSCIFSFGINAIGNDNRTIRVA
                     YPIQKGLTEIDEQGNYFGYTYEYLLEIAQYTGWNYEFVQVPGEINESITKLMKMLENG
                     EIDIMGGMLYNEPMQKIYNYAGNNYGVANTVLQALYENTDIDNIMSSQDVKKIRIAVI
                     ENSDTRLKELDEYCKMNLMSPELVYCKTNDEQLEALKSGKADVLLNVSMNPIEGVRTV
                     AKFSSKPFYFITPKGSTNLTQKLNSAINNIEQKDPYFSTTLYEKYFTPENNQMFLSDE
                     ETNYIKETEKLKVGVLLNKPPFQNIDKDTGELRGISIDLLNHICDKTGLEFELVPVKS
                     QEDLENMTKKREIDIVAGMIYDYEYSREHNIAMSRPFLSTQYTMMINNKLNENSLDGK
                     RVALAKGINYYGQFEENIVWYDNLEECIEAVNKGYADYTYGEGYSMQYYMNQPKYKNV
                     RLVPQTYKAKSICFGIIKKDKQELLNIFNKAIISISSEKMQSIVYQNTTYRQDFSLLY
                     IMQQNPIETIFIVASLLICIIGFMAFGLHTRTSMNEKISLELKKHTQLYEMTSEYFFE
                     YDYKQDKLIISMPEKGIETYYGLDKNDKESENGNIENERDKIRKEYNKKFFDVIKSQE
                     NGTTEMYSIMLDDTFHWIRVTSKIIYNDRKIPMYVIGKICNIDSEKEEKNRLLDKAQR
                     DSLTNIYNAAYIRKLTSQNLLNLSTEKNGALLIIDIDYFKSINDTYGHLLGDKVLIDV
                     AKALDESFAKNDIVGRLGGDEFSVYINDIINKEELINKCNDVYNHIHLIKLPNGESLS
                     ISMGVVIAKPGQEYDELYQIADNALYDSKRQGRNRFKIV"
     gene            complement(41410..42231)
                     /locus_tag="KR231_000998"
     CDS             complement(41410..42231)
                     /locus_tag="KR231_000998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HBH0003403.1"
                     /translation="MIDINLEKCVGCGMCESDCLVNAIKVKDDKAKVKNILCINCGHC
                     MAICPTDAIEMQGFDKNEVIEYNRESFELEPEKLLNFIKFRRSIRQYKDIEVEEEKIK
                     NIVEAGRYTPTGGNRQPIRYILVKEKLKEVKELAIQGLYNLALDTDDNDPVRSIYKNT
                     FKKMYKRYKENGNDSLFYDAPLLMVVVGDMSLGGSAYVDGGLAASNMELMAYSQGLGI
                     CYNGFFVMASNVEPKIKELLGMSENEAVITSFILGYPDVKYKRTVNRNTAKFEVR"
     gene            complement(42749..43225)
                     /locus_tag="KR231_000999"
     CDS             complement(42749..43225)
                     /locus_tag="KR231_000999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="8-oxo-dGTP diphosphatase"
                     /protein_id="HBH0003404.1"
                     /translation="MKLTTICYIEKDDKTLMLYRNKKKDDIHEGKYVGVGGKFEQGET
                     PEECVIREVKEETGLTLKSLSYKGLITFPKFKDEEDWYMFLYFSDEFEGELSEKDLND
                     CKEGNLIWVDNDKIFDLNMWEGDRLFLNWAKTGNIFSAKIVYDNGKLKDYNVSFLD"
     gene            complement(43260..43838)
                     /locus_tag="KR231_001000"
     CDS             complement(43260..43838)
                     /locus_tag="KR231_001000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HBH0003405.1"
                     /translation="MREEALEILFKYLETDRMRKHCYAVEAVMRELAKRLEPEKEEEW
                     AVAGLLHDLDSDIVGRKPGEICEGHATTTVELLKKENFGNEEMYRAILGHHDGMGVTR
                     TSLMEKAIYAADPITGFITAIALVYPDKKLTSVKTKSVIKRMKETRFASNVNRDAMRS
                     IEDIGIPFDEFAELSLNAMKNISDVLESAENN"
     gene            complement(43942..46542)
                     /locus_tag="KR231_001001"
     CDS             complement(43942..46542)
                     /locus_tag="KR231_001001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HBH0003406.1"
                     /translation="MKKIELLAPVGSFDSLKAAVQNGANAVYLGGKDFSARASANNFD
                     RNELIEAVKYSHIRGVQVFVTVNTLIKQYEIEDFVEYVKFLYDIDIDALIVQDIGMAR
                     LIKKLLPDFELHASTQMVAHSLEDVKYLQSVGFDRVVLARELNVDEIKWICENTTVDI
                     EVFVHGALCVCYSGQCLMSSMIGNRSGNRGRCAQPCRQKYELIDINTGEVVKSNGDYL
                     LSPRDLSTIEDLDKIIEAGVLSLKIEGRMKKPEYVATVVSGYREAINEFVDKKKISIS
                     EEIINNLYTIFNRKFTKGYILGEVGKDIMNSNRPNNQGLYIGKVLDYNRKNKRLRVML
                     ENTLKKGDGINLGGGTIGRIIKDGEITTIAHKGDLIELDFVGEAKRNQLIYKTSDSEL
                     MDRVQATFQQDKEFIKTNIRAKVSIKLGKKPELFISDFCGNKSVVEGDKIVEKAIKVA
                     LSKEKIETQIQKLGNTPYKLKEIEIDLDEGVSMPISVLNQMRRDCIELLDEERIKIKD
                     RKFKKNRLKYQPNRVNKQKKLDTAPKIRVKVKNLEQLEAVLNYNVDLIYYEDINTLSK
                     ALQMVSSISIDSNISIDSSISMDLDTSSSLGTPKELMGSNTNNIDTLSNTSKIDTLNK
                     NHSNTAVTDKKLIYSAPRIVRNKEYKQFEILDNIKGINKVQIGNWGSMEYFKKKDLNI
                     DCYLNVFNSESINHFKEEGASTVCLSQELNLNEIKQTLKYTDVEIEAVIYGYAPMMVT
                     EYCPMGVVVRDCKKDKRVAKCKESSYALRDFTDASYRITQDIFCRSTIYNSKVTCMLD
                     NLYELEEIGIDVFRIDFTVEDSEMVKKVIEAHIEVLSNNYKLGKKATDLYKKLDEIGT
                     VAGHYYKGVE"
     gene            complement(47112..47795)
                     /locus_tag="KR231_001002"
     CDS             complement(47112..47795)
                     /locus_tag="KR231_001002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1275 domain-containing protein"
                     /protein_id="HBH0003407.1"
                     /translation="MTSKSQMSESFFLCSLLAITGGFLDIYTYVVRGKVFANAQTGNI
                     VLFGLNIAEGNVKESFYYLIPILAFMLGVFIAEKIRKYFTNNKTKIHWRQVIIIIEMI
                     TILIVSFIPRGRFNMFVNVAISFICSMQVESFRKVNGNSFATTMCTGNLRSATETLFH
                     YIHTKNIFMIKKSLQYYAVIIFFISGAILGTFFTKIFVEKSILICFFILAVVFGIMFI
                     NKDDSFNEN"
     gene            complement(47971..48561)
                     /gene="zapA"
                     /locus_tag="KR231_001003"
     CDS             complement(47971..48561)
                     /gene="zapA"
                     /locus_tag="KR231_001003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein ZapA"
                     /protein_id="HBH0003408.1"
                     /translation="MNKVMVKIHGAEYPMVGDKSEKFMISIADFVDKEMDKITRQNPK
                     LSLSVAAILTALNISDLLFECSDENEKLIKANEELSKKVGASNEELQLEIKSLKLTIA
                     EKEAENREAETKMKELIEIIENKKQEIFELSNTTEGSRAELDAYKNKIEELSTQLEEA
                     NERATIAENLASEFQNKAYDLQLKCTGLNNDAKNVE"
     gene            complement(48586..50979)
                     /locus_tag="KR231_001004"
     CDS             complement(48586..50979)
                     /locus_tag="KR231_001004"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit beta"
                     /protein_id="HBH0003409.1"
                     /translation="MLVSLKWLRDYVDIDMDVKEFADKMTMTGTKVETIDYYGEEIEN
                     ILVGKILEIKQHPNADKLVVTKVDIGDKVVQIVTGATNISEGDYIPVAVNGSKLPGGV
                     EIKQTDFRGELSDGMMCSAAELGIDEHYIEEYKRGGIYILDHEDSYELGKDIKDVLGL
                     KDALIDFELTSNRPDCKCMMGIAREAAATIGTKVKYPEIEVKESDEEIDFKVEIDNPD
                     LCRRYVARMVTDVKIEPSPYWMQRRLTEAGVRPISNIVDITNFVMLELGQPLHAFDIN
                     QVETGRIVVRNAKDGEKLVTLDDVERTLDKDMLVITNGEKSLGLAGVMGGANSEITSN
                     TKTVLFESANFKPENIRMTAKKVGIRSEASSRNEKDLDPNLAEIAANRAAQLVEMLGA
                     GKVLKGVVDVYPNKPEPKKLVVNPQRINHLLGVDVPMEQFVGILESLEFKCNLVANDK
                     LEIDVPSFRTDMEQEADVWEEIARIYGFENIPSVQLEGNTTAGIKTSKQKFMDALKDN
                     STAVGLNEILTYSFVSPKGVDKIRVPEGNAKRNFVKLLNPLGEETSVMRTTLIPNMLD
                     VLSTNVSHKIEEVSAFECGHIFIPQDSELPKEENRMCVGMYGKDVDFFALKGTIETIL
                     VNVGFKGYEIEPQDNNTTFHPGRCAKIVYNNKYVGTLGELHPDVIENYNLGQRVYVAE
                     IDIDFVFDNSDRTKNYVPLPKYPSTSRDIALIVKDDVFVKQIEDIIKENGQGLVESYK
                     LFDVYKGSQIEAGYKSIAYSITYRSKDKTLTDEDVAKVHDKILSELSEKLNANLRSN"
     gene            complement(50996..52015)
                     /gene="pheS"
                     /locus_tag="KR231_001005"
     CDS             complement(50996..52015)
                     /gene="pheS"
                     /locus_tag="KR231_001005"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000388219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit alpha"
                     /protein_id="HBH0003410.1"
                     /translation="MQEKLLALREAALAEIKEAQSIESVESLRVKYLGKKGEITAILK
                     EMGKLSAEERPVVGKVANEVRENIELSINSKKEEINAIEKERKLKEEVIDVTQPGKVL
                     KVGKKHPITQIIDEVTDIFIGMGFSIAEGPEVETVENNFDALNAPKDHPSRDMSDTFY
                     INDGVLLRTQTSPVQVRTMRSQELPIKVIAPGRCFRSDSPDATHSPMFHQIEGLVVGK
                     DVTMAEFKGTMDIFVEKLFGSDIKTKFRPHNFPFTEPSAEVDVTCFKCGGKGCPMCKY
                     EGWIEILGSGMVHPNVLRNCGIDPEVYSGFAFGVGVERLAMLKYEIDDIRLLFENDMR
                     FLNQF"
     misc_binding    complement(52065..52299)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(52685..53482)
                     /locus_tag="KR231_001006"
     CDS             complement(52685..53482)
                     /locus_tag="KR231_001006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436797.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA methyltransferase"
                     /protein_id="HBH0003411.1"
                     /translation="MITNINSKDNEKLKYTRALLKSKNRNKESKFIIEGYRIVMLALE
                     CMANLDYVFINEEFENKKEHVKLLEDLDKKNTKIYKTTNKNFKELVDTENTQGIIGVV
                     SFKKKKLSESINKKDKFVLILDRIQDPGNMGTIIRTADSAGVDAIIALKGCVDIYNPK
                     VIRSTMGSIFDVNIIDASQDETVDMLKSLDFNIVSSYLNTENFYDKIDYGSKVALVIG
                     NEANGINEELVSKSDILVKIPIYGKAESLNAAISSAILMYEIKKYLI"
     gene            complement(53671..54342)
                     /locus_tag="KR231_001007"
     CDS             complement(53671..54342)
                     /locus_tag="KR231_001007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418257.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkA family potassium uptake protein"
                     /protein_id="HBH0003412.1"
                     /translation="MKQYIVIGCGRFGSSVASTMHLLGHQVMAIDKNEDSVQSISDKV
                     THSLIVDVTDEQALRSLGLGNFDVAVVAIGSDIRASIMATLIAKEMGVELIICKAKDE
                     LQAKVLYKIGADRVVFPERDMGVRVAHNLVSDNILDHIELDPEYSIVEIVTPNSWVGK
                     TLIELELRARYEITVLAIKTGKNINVTPSPDEELTAGSILVIIGQNTSITAITSGNKG
                     IIRRR"
     gene            complement(54629..56005)
                     /locus_tag="KR231_001008"
     CDS             complement(54629..56005)
                     /locus_tag="KR231_001008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Trk family potassium uptake protein"
                     /protein_id="HBH0003413.1"
                     /translation="MKTIVRRLILYADGMRPTQIMVSGFAAIIVIGALLLTLPIASQS
                     GESIGLLNALFTATSAVCVTGLVMVDTATYWSLFGQIVIITLIQIGGLGFMTVATMFS
                     LMARKKIQLRERLLIQESLNQADLSGLVRLTRFVLIITITIEGIGALVLSTVFIPQFG
                     LSKGIWYSVFHAISAFCNAGFDLMGSVSGPFTSLNSYVNNFTVSMTVCALIVLGGLGF
                     PVVLDIVRKRRFSKLNVHSKVVLFSTATLIFVGALFIFLIEFNQKATMADLPLKGKVL
                     SAIFQSVTARTAGFNTLDLATLRESSVFVMIILMFIGASPASTGGGIKTTTLAVLIIT
                     VRSFLSGKSDIEAFERRLAPSTIKKSLGIFVISISAVIFGTLIISITQPNFTLVQSAF
                     EVTSALATVGSSLAGTPNLNALGKIIIIIFMFMGRVGSLTLFMAILSGGRRKSQPIRY
                     AEGKIMVG"
     gene            56434..58176
                     /locus_tag="KR231_001009"
     CDS             56434..58176
                     /locus_tag="KR231_001009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase M3"
                     /protein_id="HBH0003414.1"
                     /translation="MVKSKKKIFVFLILIAVFIIFASYIRNYTNDTKKDSVRGTIPFE
                     KMEYKRPNIQSICENINKCNDKLLTAKTAKEQLNLFNEVDKIYQDFYSTLTIAKIRNN
                     IDSSDEFYSKEYKYLMSKSVDVDMSYKDFQDRFVTSKFSKELEKELGKDTFNYLKNIG
                     KLNSKEVEGLLKKEQDLVVKYEDLLAKSTVSIDGIEVDFEEALSRPNLSPEEYVKIYS
                     DYLKKYNPIFGNIFLELIQTRTEIASKQGFKNYIDYAYMNLNKDYSQEEAKKFRQDVK
                     DYIVPLYREISSKPSDSSIYIKVYKNRSFRKFDKVLEDISPKLKESFDYMKKYDLYDY
                     SSGKNKSPGGYTTYINKYKAPFLFNTWDNSFLGVTSFAHEFGHFYNYYNSINLNNKMQ
                     PSIDVCEVHSTSLEILFYKYFDDFFGKQSEAIKKEHLSIVLNTIIDACLYDEFQEIIY
                     KNPYMSLNDINKLFFDLEEEYGVSNNILREKNAPFWILVSHNFQVPFYYLSYGLASDV
                     SLQIWQLSQEDYRKAVDVYMDFLNQNTDAGFKDVVEKVNLQLPFQNGNLEEISSTLYD
                     YFGIDNPLELKNAS"
     gene            complement(58340..58534)
                     /locus_tag="KR231_001010"
     CDS             complement(58340..58534)
                     /locus_tag="KR231_001010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0003415.1"
                     /translation="MKIITIGSSLITVLLFLSTMVCGFWIKNNKVTDASSIKFHMNSA
                     IFTGIFLLISTILLIIYIKK"
     gene            complement(58531..59112)
                     /locus_tag="KR231_001011"
     CDS             complement(58531..59112)
                     /locus_tag="KR231_001011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBH0003416.1"
                     /translation="MKSNDKDARERIIEVTLNLLNEVDDIEEITVRKIAERANVGVGL
                     INYHFKTKDNLLSTAIGDVMSNIIAELYDDSVYTLRPIEDLKNLLKKLCDTGLHYEKV
                     LPFVLNQCITNGDMQAELDIVPMLRKIFGNKKDEMSLRIIALQIILPIQISALSTESF
                     QLYSGINIKNKYERDKFIDILIENIIGEDVDVR"
     gene            59280..60098
                     /locus_tag="KR231_001012"
     CDS             59280..60098
                     /locus_tag="KR231_001012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HBH0003417.1"
                     /translation="MFKIGDFSKLSKISIRMLRHYDEIGLLTPSHTNKTNGYRYYSAD
                     QLSTTNRIHALKDMGFGLYSIKEILTEYNDKESLIKYLNIHHSQVKEQLEDTQKKLLK
                     IETTIKRIGGNDIMKNYDVTIKNFAPKYMMTLRRVIPTYQDEGMLWHQVFLETKDQNV
                     QIEPPKYSKAVFYDTGYKEDYVDVEVQVAVSGKYKDTEHVKFKTVPSVTAATAIVNGN
                     FNQVADACEAIGNWISDNNYDVDGPMFNIYHVSPGNDSNPDNWVTEVCFPVKKK"
     gene            60773..61594
                     /locus_tag="KR231_001013"
     CDS             60773..61594
                     /locus_tag="KR231_001013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002572585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallohydrolase"
                     /protein_id="HBH0003418.1"
                     /translation="MKLKIVGSGGMSIIPSSFCKCKICEEARQKGGRYERLGPSLYID
                     DIKMLIDTPEDIAVACNRQKISEVKHISISHHDPDHVKGIRIVEKIGCDFITGENNPI
                     GFYALPEVIEDINRTNLDCLKYYGNVINCISINETSHVKINNFDIDLINNNPDRNITF
                     YVIKENEKKVIYACCNPKPFTHSDMYFDADVLIISLVSDDGILNDGTKLKDTPFKDEI
                     FTLDEIVEIKNYYRIKKIIITHIDEIWGKSYGYYSELEKKLDNIYFAYDGMEIIV"
     gene            complement(61904..62683)
                     /locus_tag="KR231_001014"
     CDS             complement(61904..62683)
                     /locus_tag="KR231_001014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family NAD(P)-dependent oxidoreductase"
                     /protein_id="HBH0003419.1"
                     /translation="MSYKKIAIITGANSGFGKEFLKLLINEEEITEIWAVARNKARLN
                     QLVDEFGSKVKIFSKDLSKIEEVKEIGTFLSKENVCIKYLINNAGFAKFCSYNDLSID
                     ESINMIDLNISAVVALGLICIPYMQKGSHIMNISSQASFQPLPYQNIYSSTKAFIRNY
                     TRALNVELKSKGINAIAVCPGWMSTNLFKRGIVVAEKGTKNFPGIVSPDIVAKKALKD
                     AKKNKDISVYGINTKSSHLLAKLLPQKMMMKVWLMQQHIKE"
BASE COUNT        19623 a        11731 c         7098 g        24414 t
ORIGIN      
        1 tcctattatt ctattgaatt ttattattat tttatttaga ttctattgtt attttactta
       61 gaacttatta ttattttgtt taagttctat tactattttc aatcatataa atttacaaaa
      121 gactgtacat aaatttattt tatacaaact tatctacagt cttttgtgtg aatatatcta
      181 aacaatatcg tatttattta tttcctctgc acagtgagaa tcagaaccta aaattaatgg
      241 aatatcgtat ttttttacca actctaataa gtatccatct atataaggct ctttgcagta
      301 ctcttttcta tttccagaaa cattataatc aagttcataa cctttttctt taattaactt
      361 tattaactct tcaagaattg tatttccttt ataatcgtat ggaaatacct gattaaactt
      421 tctaactaaa tttaaatgac ctattctttt tggtttatgt atacctaaat ctgaatttac
      481 agcttttatc aatgtttcat aatacttatt ataaacagct tcaatacttc ctaatttgtc
      541 gattaaattt tgaaactcct ctacactgta atctacacaa taataatcat catcaatctt
      601 aattatatgt actgataaaa gagaatcctc taattccttt ccatatttat ttaaattctc
      661 ctttatccct tcttcgtatc cttctataaa atccacttcc gacccaacat ttatcttgat
      721 tttaccctca tacttttctt tcaacttctt gacatcatta aaatactttg gtaaatcttc
      781 aatactcata caactatcat tttcaggagc agggtctcta aatccatttg catacggaaa
      841 atgttctgta aatgtcattt ctgttattcc aacatccatt gctctttgta catatttttc
      901 aaaatcatcc ttacttccat gaggacaata aggtgaatgt atatgaccat ctttcataaa
      961 taattcactc cttttttaaa gaaaaaatct aatataaatg cataaatctt ttaacttcaa
     1021 aataatattt ttaatcatgc taatttttat tatatctaat attagagtaa ttttaaactg
     1081 ccttttaagt atcttatcat tagtactatt ttcaacttaa cattaatatt attttttaac
     1141 ttaacattaa tactatcttt aaatagtaat actcaatata taattactta acataaaata
     1201 actcaaattg cttgatgagg cttttgcagt atttaaagaa tatataatta tttaacatta
     1261 aataatccaa tcttgtaata aaatttactc attaaagtat attacagaaa atacctcaaa
     1321 ataaactttt tagttcatga tatactcttt tttgcatgaa attagatata tttttatcat
     1381 ttcaacaatg aaagggaggc ttatatccat ctttagacaa ccccttagat aaaattttta
     1441 ataattaaac atcacaaaat ataaaaatcg cttatatcaa acgtataagc gattaattat
     1501 atttacatat gttttttagc ctctaacaac attttattag cttcttccat atactctata
     1561 gccttttcaa tactctttgc tgtttcttct tttccaatag ctctagcctt ttcaacccac
     1621 tctctaaatc cttcttcatg agtttcattg tgatttatcc aatgtactaa aagtattttt
     1681 aaagtttttt catccttaga ctctgatgat tcctcatgac tatgttcgtg gtcgtggtcg
     1741 tgagcatggt catgtggatg ttcatgacat atatctccat gagtatgttc gtggcagtgg
     1801 tcatggtcat gatgtccatg atgatatctt acaatctctt tatcaaaaat cattagttat
     1861 tccccctgtt attttatatt aaactctttt tttataaggt ttacagaatc ttttacaagt
     1921 agtgctaatg gtttaccttc taatccaact aactccacat tttctggcat aataggtaaa
     1981 agtatcttaa gtgcctcact gtctgcaata gcttcactta tattacaagt aacttctccc
     2041 atcatagaat taggtattat tacagaaata ggtgcaacta ttatatttgc ttttttagct
     2101 gatactacta tagcattttc ccctgtagct cctttattag catgagcttt catcatagaa
     2161 ctagttgcta tagaattagt ccctagtgca taaatttcta catatgtagg taactcttct
     2221 ctcaaagaag aaactatctg ggctccaata cctccaccca ttccatctat cactgctatt
     2281 atcatatgaa attcccctat taattaattt tcttgtatta ttatcttatg gtccatcaat
     2341 cttatttctt taattatccc atctattatc ttttgctctc ctaataaatc cgttaaataa
     2401 atctttccat cacaagggtc tatattaacc acattttcca taaccttttc taactcatta
     2461 ttacttttac aaatgaaagc tgatgattca cacatataaa tctcctccta atatgatttt
     2521 tattaaaaat caaaaaaaga ttcccttagg tatttcaata caccaaagaa accttcatga
     2581 tttcagtttt tgtatattat tataccttaa gtatatcact ttaatttatg taaagtcaat
     2641 taaagttaac gctttttatt atactcttca ttcttgtatt tttcatatag ttctttaact
     2701 aattgcttct cataatcagt caaatcgccc tccacaaact caacattaaa ttgttcagct
     2761 aatcccttta ctatgttttt ctgtagaata tctatgtcta tttttctgcc aatttcattt
     2821 tctattccac ttgctttttt agctgtaaat ttcatagctc tttctttcaa ttctggtgtc
     2881 ttagttttta ttaatttaaa caatttttct acatcaaaat ccagtattat tgaaccatgt
     2941 tgtaataaaa caccatcttt tctgctttga gcacttccaa ttaccttctt attattaata
     3001 gtaacttcat atgatgcatg tgcattaaaa catgcagctg ataaattttc cctacttatt
     3061 ctctcgcctc tatttaaatt atctgtttct ataccactta gattcaaccc tttaactaga
     3121 ccttcactta tatatctata agataggttg atgctcttat cgattaaagg attatcttct
     3181 cctataatta tactataagt tagctcatta tcatgtaata cagctcttcc acctgtaatt
     3241 cttctagtat agtctatatt catacatcta cacttatcta aatctatctc atcttccaat
     3301 ttctgaaaat atcctatact caaacaagct ggttcccatg tataaaatct aagagttggc
     3361 ttattatgtc ccttcttata tgcagtaaat atagcttcgt caattgccat attcattgct
     3421 ccttcatatg atttattatg tataactctc cactgattca tgattattac gcccccattt
     3481 ttagtataaa tatatcctag aaatcctcta tagatttatt tctcttattg ctaaatctat
     3541 ctcactttga tttaaaggtc ttgaatagtt gtatatagta cttcctggtc tttcattata
     3601 gtatggtcta ttacaatcct tacaacctct tatttcaaaa ggatagcctt tgtttatgtc
     3661 ttttaaaata tcattgtcaa gctttatact atttaagtat ccatttttaa acttaaaata
     3721 ctcttttgga taacctttat ttatcatata agacattaac tgtacccttc tataactttc
     3781 tatgcttggt tgatttatct tttccatttt agttcctcta actggagtaa atgcaaataa
     3841 actaatcgtt acatcatttt cctttaaata agtatataaa ttgtatatat cttcatgact
     3901 ttcacccata ccaactatta tatgtgtact tattttattg ggatatgatt ttgacatttc
     3961 agttataaat tttaactttt catcatagtt atttcctttt attttttcat atagttcttt
     4021 atttgctgca tctattgcta ttcctatttt atcaactcct actgaaaaaa acttctttat
     4081 ctgttcatca ttttctaatt ttgcagatag tgaaattggc atgtctatct taccacttat
     4141 atagtttata aagtctaaaa cagagttatg tgcttcttca cttgccattg attgaataca
     4201 tattctcttt atattttttc ctttataagc ttttaaagca tctaatattt cttcttttga
     4261 aaactctggc caaattactc ttgataattt atcttttcta gtactacttt ctattgattg
     4321 agaacaaaaa ctgcatttat ttatgcattt ttctccaatc attatatatg ctgtggtagg
     4381 aggtatatcg ctttttttgt ttaatatccc aagttctatt gctgtcccaa ctgatagtct
     4441 aatcataaaa cgcaacactc cttacactca tttattgtca tattcatttc tatagcctta
     4501 ttctttgcag accttgatgg taatactatt ctattgactc cacacattat agataattgg
     4561 tctagctctt ttctatacac tcctcttggt ctcatacaac ctagattaat ttcagtatct
     4621 ggtaaattaa ttctagcttc acataaaata tctgctaccc cttctaactc aggaggttct
     4681 acattttcat actcagtccc ttttgttgga ataaggacta taaatgtaag cttattagga
     4741 ggattttttt gtaggtattc tataatttca tattcaccct ttatttgtcc tccttttaaa
     4801 ccaatacata tatgtggtgc tacttctgta tgttcttgta ttgtattata gacttcaata
     4861 taatcttctt tactcttttt catcttataa acttctctta ttgtctcatc atcaaacact
     4921 aaatcaaaag aaactatatc taaatactta cacaactcta caatgctatc tttatccata
     4981 agacctaaat gagcattcaa tctatatcct tgctctttta agtttttaat ggtattaata
     5041 tgagtattta tagggacatc tccctcataa ctacaaccgc cactcaatag aaagctagtt
     5101 atattccttg attgtacttt ttcctcatat tcttctattg gcaccatatt gtttaagtag
     5161 tgaccgttgc aatgggcaca tttcaaacta cattgattgc ttgtagtact aagagctagt
     5221 gtctggttag gataagcaaa ctctatttta tttccaaaat tctttaattt aatatcaaat
     5281 gctatttcca ttttttcaga tagattctta ttcatagttt attccttctt aagtacattt
     5341 tactcttcta gtaatttctt tgctgttggg aactgctcta tattcgtatg tggtaagaaa
     5401 catgcagaaa taaattcatc catataactt ggatatacac taagttcaac ataagttatt
     5461 tgattaccta tttcttcaag tttatttttt gcatctttac ttataagagc taagtaagaa
     5521 ccaacaagtg aactattccc tatataagta aatttttctc tatcaatatc aggaagtaac
     5581 cctataatta ttgagttttc tatgtctagg ttgtttccta taccacctgc tatataaacc
     5641 ctatctaata tactaaaatc catacctaaa ctatctacaa gagtgtatgc gcctgaatat
     5701 atagctcctt tagctctgat gaaattatct atatcaactt cattgactac tatatcattt
     5761 tctaaatcaa attcttcttt aaatgctaat acatactctc ctatctcatg ctcattaaat
     5821 ctaactctct tattatctaa atccctgtat attttacctc ttctatctat taccccttta
     5881 gtaatcattt gacagattaa atcaattata ccagaaccac atataccaac tggtgcacat
     5941 tcatcaataa tctttaatgt tggctctaaa gtttctttat caataattac tttctctatt
     6001 gctcctgctg atgctctcat tccacagctt atccctccac cttcaaaagc aggtcctgct
     6061 gaacatgcac agctcatcat ataatcttta tttccaaata caatctctcc attagttcct
     6121 aaatctataa ataaaacatt ttcttcactt gaccatatcc ctgctgataa tacacctgct
     6181 gttatatctc ctcctacata acttgcaaca gatggagcta agtacacata tgcactgtca
     6241 tttacaaaaa gaccaacatt ttcacccata agttttggag attttaaaaa tggtggtatg
     6301 taaggttctt gtcttaagaa gtctgtatac acacccaaga ataaacttgt catagttgta
     6361 ttcccagcag ccactaatgt aactacatct tccttatcta ttccatttct ttcatatatt
     6421 gtttttaata gtggatttat agtttcctca actatagctt tatgaagtgt ctctaatcca
     6481 tttttcttag ttgaatatat aattctattt ataacatctg ctccatattt tatctgtgca
     6541 tttccagaag atgctttatc tactacctct tttgagtata ggtctactaa acaaacaact
     6601 actgaagttg taccaatatc tattgcaact ccgtataagg aattttcttt atttccttgt
     6661 tctatattta tgattgtaag tttcttttgt ttttgaacat atgttattgt aaccttaaaa
     6721 tcactctttc taaatacagt tggcattttt ctaagtatat ccaatctaaa atctatttca
     6781 ttatatccta ggttatttct aacatatctt tccaatctat ctacatcact tatattatca
     6841 tctaaatttg gttcttccat ttctatgtat ttctttttta tatttgtttt aaattgaagg
     6901 ttatgttctt caattatttt tttagctctt tcaaaaattt ccctatcctc ttttttatta
     6961 ctaccttcta tcttcatacc atgcatagaa gatgatactt tagaaggaac ttcaatttct
     7021 atatctgata ttacctttgt acaacaagct agtatataac cttgctccca ctcatcatct
     7081 gttatatgtc ttgttttttc tgtatcaact tttccattca ataattttac tttacacttc
     7141 ccacaagaca cgtttccatt acaaggagca tctatgaata tatctgcatt tcttgcaacc
     7201 tctagtaata tatccccctc attacaataa acctctttat tgtttggtgt aaaacttact
     7261 tttatcatgt tatccctccc aatttgttct atatatgata aaaggaaagt atagctaaat
     7321 ttgcgtgcac tcaaatttta ctatactttc cccaattata ataatatctt aatctttaat
     7381 tattctaatc cagcctcgta ttctttatca cttaataacg tatcaagttc agccacatca
     7441 gctagtttta cttttaatat ccagttttca tatgggtctt catttataca ttctggctca
     7501 tcttctaatt tttcattaac ttccaatacc tcaccattaa caggagatat taaatcagaa
     7561 gctactttag aagactcaac tactccaaaa tctactccct tagttacagt atcttctact
     7621 tctggtgttt caacaaacaa tatttctcct aattgatctt gagcatagtc tgttatacct
     7681 atatatacaa catctccatc aattactttt acccactcat gatctttaga gtattttaat
     7741 tctggtaata atttcatttc gatagacccc caatattata ttattgatta aattacttaa
     7801 atcatattaa tattatatca tattatttta aattttccat caattacatt acactttcca
     7861 tagctaatgc tggatgacct ttttcttcta agaaagctaa tactccttca gaatcgtcag
     7921 ctatagtttc atcacaaacc atatcacaga agttttctat tccagtcatt tctttaactg
     7981 tagcatttaa tttatcagct acataatctt ttaattcttt tggcatccaa actattcttt
     8041 ctggtccacc ttctgcataa gcgaattttt tagaagatat gaaatgtctt ccgtgtccca
     8101 taaatcctgg agtttgaact cctccacctg tcatagaagc aagttctccg aaagtcatac
     8161 caactggagt aacacttgca aattctctgt taactacaac aaatccattt gcttctggca
     8221 ttataccaca gatacattcg aagcatccac aagaagtcat tgggtcttct agtatagagt
     8281 ataatgtaac agattcaact gcaccttgag atatttggtt tacagtttca tttactgaat
     8341 tccatacacc tgttctatca tctaagcact cgcctttttc tattggttga caaggacctg
     8401 ttgggtctaa ttctttagta gccttagcat ctaaccagct aactgctcca caaagaccaa
     8461 gtctttcagg agtaacaaca caaacgtgag ctggtgcaaa tgattgacat aagttacaag
     8521 aatagaaagt atcaacactt tcatcaacta atgaagctaa tctttcatct ctagcattgt
     8581 acttagctat tgcttctcct tttaattcag aaactttttc agcatctgta attatagtta
     8641 tttcacactt atcaactact gattcaaatt catctaacat cttagcatat aaaacttctc
     8701 ctatatgctc aagtctaaat cctttatcaa atgcatcttt agagattctt acccaagcca
     8761 tatctctttg tccaacgtgc attacacctt ctatatagtt taagaagtag tggaaacgtc
     8821 tttcaagaac tggctcgaaa tcttcttgca tatttttacc agctatttta actattacag
     8881 caagtggtaa tcttaataca ccatctgcat caacttcatc tatatttggt cctattattt
     8941 ctatcttatg gtcttcaact tctgttgctt ctttcttaac aacaagctcc caagcttcag
     9001 ttctgtttcc accaaactca gcaaacatat cgctctttct aattctctca ccttcaaatg
     9061 ctgctgcaaa tgaaactggg ataggtattt cagtaacttt tatttttatt cctctagctt
     9121 ctaatgaagt agctactatc ttatcgtaat ctttttgagt taataggttc attggaactt
     9181 caagaactgt ttggtcagtt ataactggga atcctaaagc tattgctcca gcacctgcag
     9241 atacaactaa ttcacttaat ggtccaaatg cattaacaaa tgcaggaact ctattagctg
     9301 tgtactctaa taatccgttt aaatcaccag gagttaatcc accgaatatt aatgctgctc
     9361 ttactgcaac agatacaacg tgtataacag aagttacatc atatcctaga ggtataactc
     9421 ttagctcaag acccattttt actccagctt ctatagcttg gtctataact ttaccaacta
     9481 agaaagttag taaaccttta gattggtaat cttttataac ttttgctgct gattctgcat
     9541 ctggacactc accaagaaca actgcaacac caggtatatc tcctgtaact aatggtacac
     9601 caagtgatct gattataggg tcagttatat gacctgcaca tggctcacta tatggagcat
     9661 ccatagttga atattttaat gcttcaatta cttctgctgc taaagctgta gctaaaccag
     9721 cattaaaagc atgttctagt aaatgagttc tatttattaa agattttact acttctaaag
     9781 caccttctaa gtcccctaaa gtgttcatct tttgtcctgt tgcagcatat atacaaggta
     9841 atgaatatgc tgtatcaggg aaagcaactt tatgctcttt tccattcttt tctatagctt
     9901 cagctaacat agcttgagcc gcacctaaag cttgttctga ccctgtaaag attatattat
     9961 atagattcat tctatttccc cctttaatat ttacacctat tttttattaa ctatacccta
    10021 aaaaccctag aaagcaaatc caccttcatt taactctaag aaagagtctg catataaaga
    10081 tgccccgttg attatgtcac aagattttac agttttcatt aattctgggt cacatggatt
    10141 cattatagct gaactaaatc cattagccat tgccattgct aagaatgcac tatctaaaac
    10201 aggtctaaca tgcttaggac atccattaga tacgttagat aatcctcctg tagttaaaag
    10261 tcccatctca gtcatcattt ttatagcttc taaaacttct acttgttttt cttgcatacc
    10321 ttttataact aagcataatg ggtcaaatag tatatcagtt ggctccattc ctaacattaa
    10381 gcctttttct aatatttctt ggcagtaagc catacgctca tcattatctc ttgggatacc
    10441 ttcttttgca cataaaccta taaccattgc ttcgtattca gctgctatat ctattaaatc
    10501 aaatcttgaa ccagcatcag cagagtttat tattggtttt gcattagttc tatcataaac
    10561 tttaagtcca gcttcgatag cttttttatt agctgtatct aatgctatag gaacattgtt
    10621 gaactcagat tgaagtaatt tgattcccca tgtcattatt tcttcgccat ctctttcggc
    10681 aggtcctata ttaaaatcta tatagtgtgc tcctgcttct aattgctctt ttgctctttt
    10741 taagattgga gctgggtctc tttctgctaa tgcttttctt attgaaggtg atatacaatg
    10801 tattctctca cctataatca taaatttttc catttataat gtcccccttt aaatttaata
    10861 ttaatagtta gttaatattt tattagtttg tttggcatgc tttttcttgg tatcctttta
    10921 agaacttagg taattccata gattcctctg gtcctataac tacattccat cctggtaagt
    10981 tatcttctat atcaccttta agtactgcaa cttttcctgg aatgataagg tctttacaat
    11041 tagttacttc ttctacctta ctttctttaa tgaaagcaga gattgagttt ccaccaaatt
    11101 taccagcagc ccaagatgta agaactgaat atccacctgc atctggtatt actaaccata
    11161 ctggaacttt tgatctttct atatcaccag caactatgaa gtaagttaat gcaaagtcaa
    11221 cagtaactaa tactggagaa ttttcatctg ggttgttgat tggataaatc tttggttcaa
    11281 ctctcattgg tctttgtggg tcagtgtata tgttttgtct tagtgcaaat aatggtaatg
    11341 ccttagcata actaatatca tctattacta ttatagaacc gtattttata gtgaatattg
    11401 atgataaagc aacttccatc atagggtttg aattagataa tctatttgca aatactattg
    11461 aaggatatcc aaatgttcta tcttgctctt ttaaagctgt tcttctaact tgtatagcat
    11521 tagtgtaagt atcttttatg ttttctcctg ttacatctaa tactaattct ttatatccag
    11581 cagcttgaat taattcaact gtttcatata attcttctaa gctaccagct tttacaccta
    11641 atggtaaact tgctccttta actacttcta tcatatcttt gtagttctct ttagttgctc
    11701 catataccat tggtctagca tcttttaata cttcaacagc ttctttaact acttgtgcat
    11761 catcacaagc taaaatataa gctacttcta atccactgcc ttttatttta tctattaatt
    11821 ttaaatacgc atctttatct ccacaatact ctaaaacagc catttcaact ttcatttgtt
    11881 caccaattct tacatagtca acttttttca tgttagctat tttagcatct actgcttcat
    11941 cactcataca agtacagaat gaaactgcat atctatttct acttactaat gttttttcat
    12001 gtctaaataa tactgtttct ccacctagtt catactcaga tgcaccagca ccaactttta
    12061 aagctttcat taaaggtgca gtagcctctg ataattttgc tatagcgtca tcagacatat
    12121 gtgggcattt acctacttct acagctcctg aagcaacctt catagagaaa gccatacaag
    12181 ttgggaatcc acaatcctta cagtttttct ttggtgttaa tttaaatata tctaaagctt
    12241 ttaatgccat tattttttcc ccctaacctt aacaatttaa ttaagctaat gcgttaacca
    12301 attcttttat agtttctatt gattttggat gacgaagtat aactgcgttt gaaccaccta
    12361 ctaaaacact tgctgcagtt gaaacttcca ttgctatagt tctttcttct ggacaacccc
    12421 aatctggctc atcttctatt ggagctatag cttctttaac atgacctact tcaaaagcta
    12481 ctggtgttat gataggcatt tgtaatgtct tatcattttg accaaatgct gcaagtctaa
    12541 ttctatccat agtagatgca acgtactcat atccataacc aactgctgaa catccaacat
    12601 tcataactat attttcacct ttaacgccta gttgagttaa caatacgttt aattgtttag
    12661 ctaggtttat atcaacagaa gattcagctc ctactttatg tgcataagcc ataccagctg
    12721 atgctcctac tcctttgtag ttatcttcta ctgctgacat aaataagcag ttatgtccat
    12781 ccaatgtttg agctaatttt tcaaataatt taccatcttt ttcatgattt cctgaaccag
    12841 ctacaactaa aggtaatttt attgcttcaa ttactgcctt agctacatca gcacattcat
    12901 caactgactt atctaatcca tttgggtcag aaccatcaaa ttttaaacaa ataaaatctg
    12961 cttgtgtatt agcttcaaca tatttagccc actctactgg acaattagct acatctttgt
    13021 ataattcctt atatgaatca gtccagcttt caggataaac atctgatatt tgtatcccta
    13081 tttttggaga attacctact tctccatcaa aactataaaa aggtaataca ttttccccac
    13141 ctaatttaat tgctttttcc cctattccta cttcaacttc tgatattttt ccagaatatt
    13201 tttgagtaga cattttaaat gccatatttt tttccccctt aagcctattt taattctaat
    13261 ttagcaaaaa tttctttcat agccacttta gattttgaat cttcaggtaa attaactaaa
    13321 ggaatacctg tagaatcata ttcatatatc aattcatcca taggtacaac accgattagc
    13381 tctaggttat gcttttcaat ttcttcttta acaccatcat tcataacccc atttggaact
    13441 ttatttacaa tcaaaagtat tcttccaaca cttaacttta gttcctcagc taaatctctt
    13501 attctagcaa cagcttgtat gctacgtctt gagcaatcac taaccaataa aagtgtatca
    13561 acatgtctag tgacttttct acttagatgt tccataccag cttcgttgtc catgactaag
    13621 tatttgtaat gaccagatat tttgtttact tgttctctaa gtatcccatt tacaaaacag
    13681 taacatcctt caccttctga cctacccatt actaataagt catatccttc gccttcttcg
    13741 attatagaat ttaatctaaa ttgaagatat tgtgcctttg tcataccacc agggaatgca
    13801 ttgcctaact tttctctttg atttacttct tctcttattt ctcctattgt tgcttcaact
    13861 tcgataccta atacttcatt tatgttagca ttggcatcag catctacaac taatactggt
    13921 ccctttttgt ccttaaccaa ataatcaatc aaaagccctg tgagacttgt tttaccagtt
    13981 ccaccttttc ctgcaacagc tatattgtat cccattttaa gacttccccc ttaaatctag
    14041 ccacagagcc ttatgtactc tgtctgtcta ttataattta ggtacagaat gaacacattc
    14101 tccatgtaca tcatgaagtg cttccattag cccttcagat aaacttggat gtggatgtat
    14161 tgcatcccct acttgttcta ctgttaatcc tagatgaaca gcaagtgaca actctgtcaa
    14221 taaatctgta gcatgaggtc ctactactgc tgcacctatt atcttatcag tttctttgtc
    14281 agctataact tttacaaatc cttggaaatg tcctatagct tgtgcttttc caagacctct
    14341 aaaatcaaat tgacctacat tgtattctac accttcagct tcaagttgct tttcagtctt
    14401 accaacacca gcaacttcag gttcagtata aacacatctt ggaattgctc tataatctac
    14461 taccttagtc ttacctaaag cattttcaac tgctacgata ccttctttag aagcaacatg
    14521 tgctaggaaa ggagtatcta ttatatcgcc tattgcgtat ataccttcta cattagtttc
    14581 aagatgttca ttaactacta cttttcctct ttccatttca attcctatat cttctactcc
    14641 agaattgtca aggttaggtc ttctaccaac acatactaat gcatattgtg cttctataac
    14701 ctttccatta gaaagagttg caacagcctt accatcaact acttcacaag tttgtactcc
    14761 aatacctgta ataaccttaa ttttatcttt cttaaattgt ctaagtagtt gtttagctac
    14821 atctttgtct tcatttaata gtatttggtc aaccatctca actatagtta cttctgttcc
    14881 caaggctcta aagaactgcc ctatctcaca tcctataact ccaccaccta ctattaacat
    14941 agactcaggt atctcttcaa gtccaagaac ttcatcacta gttattacaa cttttccatc
    15001 atatgggaac attcttggta caactggaac agaaccattt gctagtatta tcttatctgc
    15061 ttttatagtt tctactgttc catcatcttt agttacttct atagtgtttt tatcaattaa
    15121 ttttccaaaa ccattaacta agtttactcc tcttttttca aataagaact ctataccact
    15181 tattaattgg tttacaactt tattttttct ttccattatg gcagtgaagt ttggcttaac
    15241 tgtaccatct atttctatac caaaatcctt tgcttctttt acagtattca atactcctga
    15301 agaagcaaga agtgctttag ttggtataca tcctgcattt aagcaagttc ctccaactct
    15361 tcttttttca acaactgtta catctgcacc aagcatagaa gcttttatag ctgctacata
    15421 tcctcctggt ccaccaccta ctactactat cttcatcttt aattccccca aacctaatat
    15481 aatctacaat cttgcaatac tataaacctg cggcatccag tatagcaggt atattctctt
    15541 ctgccccaat tgccattata tgaacaccat cacataaatc ttcttctttt aattgtttga
    15601 taagttcccc tgccattttt attccttcac ttacccagtt ttcttttcca gctgctctta
    15661 atctttcgat ttgttcatct ggaacaaata ttcctggtac atttgcagtc ataaatttag
    15721 ccattcctgg tgattttaaa ggtactattc ctgctaatac cttgcaatcc atatcccttg
    15781 ttaattctct aaactttctc attgtattta tgtcataaag tgcttgtgtt tggaaaaatt
    15841 tagcccctgc ttttattttc tttttcattt ttaataattg aacttctatt ggagaatatt
    15901 ctggagttac tgatgctccc agataaaaat ctggagaacc ttttaactta ttaccagcca
    15961 tgtccgtacc tgccattaaa gtctcagcag tttgaagtat ccccacagaa tctaaatcaa
    16021 acactccctt agcttgtgga tggtctccta cgctagtatg gtctcctgtt agtgccaaca
    16081 gattgtttat cccaaataca cctgctgaca acatttctcc ttgtatagct attctatttc
    16141 tatctctccc tgttatttga ataactggct ctaatccagc atcttttaat aatttacatg
    16201 tagcaagaga agttgctctc ataactgccg attgaaagtc tgttacattt gctgcatgaa
    16261 ctcttccaac taacggcttt gcacattcta ttaaatgtga aaggtcagtc ccttttggag
    16321 gagccatttc agtagtaact gcaaattttc cactttctaa tgtttctctt aataagctca
    16381 tctctaatcc cccttttaac cttctaaaaa aaacttttat gaatttgctg ctgcttcttt
    16441 ctttttcttt gcacttaaac ttcttggatt attttgctta gaatagtctt ttggtggtct
    16501 tatttctgct aagttatcta attgtcctat agcttctagt ctttcatata tctttatcca
    16561 agcacaatca ttctctgagt ttacttcaca cttaccattt ttagctccac cacaagcccc
    16621 attcataaga cctttagcac acatagttac tggacatatc ccacctgtcc aaccaagttc
    16681 acagtctcca caagccttac aggcttcttc atattctcca actctttgta cttcccctat
    16741 aaacaaagta ttgttggctg gataaactgg cttatctttt aaattcttaa ctattgtctg
    16801 tgtaccatct ccacatgcta aagataaaac tgcatcagct tccttagtct cttcctttag
    16861 agcctttaaa tcctttttag actttaaaag gttacaagca gggtcaagca ttacatatcc
    16921 taagattttt ttgccttcac cttcaagagt ttccttcatt tttaaaactt cttcttcccc
    16981 accactttta caagttgctg cacattgatt acaaccaact aaaaccagct tgtcaaaatc
    17041 ttttaagtac cctagcactt cttctaatgg tttattttca gaaattatca tatctacttc
    17101 ccccctaaac cttccacata tatatatcta tttattgttt tgtaatttac aagccttaac
    17161 tacatgtttt gcaagtatag atgttgtaac tgaaccaacc cccgctggaa ctggagttat
    17221 cattgatact ttgtctaaaa ctgcatttgt atcaacatct ccacataaat ttccttcttc
    17281 atcaacattt ataccaacgt ctataactac cgctccatct ttaacaaaac tttcatcaac
    17341 catcttagct ctaccaatag ctgctattag cacgtctgcc tctgctgcta cacctgatag
    17401 atttttagtt tttgaatgac atattgtaac agttgcatgt tcacttaata aaagcattga
    17461 tactggcttt ccaactacca ttgatcttcc aagaactgtt accttacttc cttttaaatc
    17521 aacattatag tgttttaata tctcaactac tgctgtaggt gtacatggtg gaaatccact
    17581 tttatcccct tccattacct tagcagagtt tattggacta aaacaatcta cgtctttttc
    17641 cggtgcaata acatatttta taacttcttc atttaagtgt tttggaagag gtctaaaaca
    17701 taatatacca ttaacatttt tgtcatcatt aactctcttt aatacatcaa tatattcctc
    17761 ttgtgttata tcctcagcta actctaacac ttctgttgtt atacctatgt tttgacatct
    17821 ctttagtgct cctctttcat aagataaatc atcacttctt gccccaactc taactattgt
    17881 tagtttagga tttatacctt ctttaattag taaatcgact tcttttatta attcttcact
    17941 aatcttatca gctacaggtt ttccttttat aatttgtcct ttagttgaca ttccttccat
    18001 acattcacaa ctcccctaca agcaaactta aattaattta ttctatatac cacatattaa
    18061 taacatagta tctactttcg tcatttaaaa attattttcc aagagctttt tcaactttgg
    18121 cataaacttc atcacaaatt tttacaccat cttcaactaa cttatctact tctgttttta
    18181 ccttattaac atattcttta tcttgtatag aatttatatt tataactaca tttaattgtc
    18241 caccaagtat agcagctctt aaacactgaa ctcctacacc aacatcactt atagcaagtc
    18301 ttgaaccttt atcaactaaa tcttcatgta acttaatagc ttcatagcaa actcttacta
    18361 tgtttaatgg tacttcacaa gcaactttta atgccttttc cattgtttct gcttttattc
    18421 ttttttcttc ttctgtttct ttaggaagcc cgtaagcttt tgataatggt aagaaacatt
    18481 ctgcatcatc atctatcatt tttaataaat ctttttctaa ctttcctgcc ttacttaata
    18541 tctcttttac actttcttca tactcagcat acttcttctt ccctattgta aggttacata
    18601 ccatactacc taaagccata cctattgcac ctactagtgc agcagctccc ccaccacctg
    18661 gtactgcttc tttggaagat agtacttcta caaaatcaac acaagtttta tctgctattt
    18721 tcatgataat cctccttgaa aggatgtagg aaaatatctc aaattgttcg agatatttta
    18781 cgaactattt taagatatct cctactcttt atttataaat taatttcctt agaataatcc
    18841 agctattact ccattttcat caacatctat tttttctgct gctggaactt ttggtaatcc
    18901 tggcatcttc attatttctc cagtaagtgc aactataaat ccagctcctg ctgaaattgt
    18961 tgcttgtctt acagttattc taaatcctgt tggtctacct aatttagttt ggtcatcagt
    19021 taaagaatat tgagttttag ccatacatac tggaacttta gtaaatccaa gtttttctaa
    19081 gttagctatt tccttatcag cttcaggagt ataatctaca ccatctgctc cataaatctt
    19141 agtagctata gcatttatct tgtcttttat agataaatca tcttcatagc agaatctaaa
    19201 gttattttct tcttcatcca ataatcttaa aacttcttta gctactgcaa ttccaccttc
    19261 tccacctttt gcccatactt cagaaagagc aacattaaca cctaattcct tacacttgtc
    19321 ttcaacaagt ttaagttcag cttcagtatc aagtgggaat ctattgattg caacaactgc
    19381 tggtaatcca tatacttgag ttatgttttc aacatgtttt aataagtttg gaagtccttt
    19441 ttcaagagct tctaggtttt cgttatttaa gtctgcttta gcaactccac cattgtattt
    19501 taatgctctt acagtagcaa ctattataac agcatctggt tttaagtttg ccattctaca
    19561 ttttatatct aagaattttt ctgctccaag gtcagcaccg aaaccagcct cagttattac
    19621 ataatctgca aagtgcatag ccattcttgt agctataaca gagttacatc catgagctat
    19681 atttgcgaat ggtccaccgt gtacaaatga tggtgttcct tcaagagttt gaactaggtt
    19741 tggttttaaa gcatctttta ataatgcagc catagcacca ttagctttta attgtctagc
    19801 tgttacaggt tcaccttcgt agctgtatcc aactattatg tttcctaatc tttcttttaa
    19861 atcagatata tcacttgcca aacagaacgc tgccattatt tcagaagcaa cagttatatc
    19921 gaatccatct tgtctaactg ctccatcacc ttttttaccc ataccatcaa cgatatttct
    19981 aagttgtcta tcgttcatgt ctacacatct tctccaagtt attttcttag ggtctattct
    20041 aagtgcattt ccttggtgaa tatggttatc aagcatagca gctaaaagat tgttagcagc
    20101 tcctatagcg tgaaaatctc ctgtgaagtg taagtttata tcttccatag gaacaacttg
    20161 tgcatatcct ccaccagctg ctccaccttt aacaccaaat actggtccta gagatggttc
    20221 tcttaaagca actaatacat ttttgtctag tttagcaaat gcatcagcaa cacctatagt
    20281 agtagtagtt tttccttcac ctgctggagt tgggtttata gctgtagtta gtattaactt
    20341 agctttttta ccagtctctc tttttagtag attgtagtca acttttgctt tgtatttacc
    20401 ataaagttct acatcatctt cacctagtcc taattttttt gcaacctctc taatatcttg
    20461 aggcttagct tcttgagcta tttcaatgtc agatttaaat cccataactg aatctcctcc
    20521 cacaacctaa atagatttaa aatataattt ttgtaaaaat tgtattaata tgtaaaaatt
    20581 atattttata agataattat acatgtaaaa ttacttaaaa actagctact aagctattaa
    20641 aatattcaaa cttaatagct agttatttat ctaattactt acttattacc tatctattgc
    20701 ctatgtctaa cctttaacca acttaaaatc ccaaatcaaa atttctatct attttactta
    20761 tccttaagtg acattaattt atcttttatt gctttaatct gttctttcgt tgtttcacta
    20821 gaatcatatg gagattgatt agctctatca gaatcaataa catcttggtt ataataaata
    20881 aatcctaaag attctccatc ttctaagttt tggattataa attcttcatc ttccttattt
    20941 ctaattttat ttcctactac aaatacttta tttacaccta tatcatgtcc aagtttctta
    21001 acttttctat aagtctgtag acttctctct cctggttcta caactactat aaaagcatct
    21061 acaccttggg ctgttcctct tcctaagtgt tcaattcccg cttccatatc cataaccact
    21121 acatctttat tttgtagtat taaatgtgag cagagtctct tcaaaagaac atgctctgga
    21181 catacacatc cagtaccacc agaatctacg gttcccaatg taagtaatct tactccattg
    21241 tattctttac agaaattttc agggatatcg tctactttag gattcatctt aaacattttt
    21301 ccaaatgaac ctacagaagc agctgttcta tctgaaacta attttttcat ttctgatata
    21361 ggtactattg attcatatac ttcttttgga aaacctagtg ctaaagctaa attagcatca
    21421 gggtcggcat caacagcaac aactctgtat ccgtcttcag caaacatcct agagagcatt
    21481 gaagaaaaag tcgttttacc tactccacct ttacctgtta ttgctatctt cataatccct
    21541 accacctttt attactattt gctttttagt agttaatttt acagttaaat attttttata
    21601 ctctatattt ttatacacta aaaataaact acagctagtc cttacaggaa ccaattaaat
    21661 ttaccctact agcttttcaa agcagcatgt atagttttat tattctttaa tattgtttat
    21721 attttattta ttcagtatat tcattatatt ttgatgttct ttactttaat atttgacttt
    21781 attcaacttt attcaaccag aaacttctta taaaaacgtt tattctataa cttcactatt
    21841 ttttaagctt cagccttttc tgccattttt tcttcaacta atgcttcaaa gtgaacacgt
    21901 tttttctcta tatcttctat tattgtagct gctaactctt ttggatttgt atttacagta
    21961 aatgtagctc caactttatc ttttaattca ctagttaata tatccactgc tcttgaagaa
    22021 ccagctattg gaggcattat tcctaaataa gtgtctatac cagaagctac aacatagcat
    22081 cctatagcaa ctgctttttc tgacatccac tctggagcta tacctacaac tggaaggtca
    22141 cacatatcca tatctaagta attagctgct gctccaacta aatctagtat acggcttata
    22201 tcaacacaag aacccatatg tagtactggt gggattccta ctaatttaca gacagttgca
    22261 agacctttac ctgcatattt ttcagccgca tcagattcca ttaaaccaaa cttagctgct
    22321 gctgaagctc cacaacctgt agtaactact attatgtcgt ttttgattaa ttctttcatt
    22381 attgttacgt gagcctcatt tgaaactcct ttagcattgt tacatccaac tacaccagct
    22441 gctcctctta atactccagc ttttaaacag tctgttaatg gcttaactgt tcctgctggg
    22501 tctatatgag agtttacaac tctgtctaat tgatttacta ctgcttctac actataccca
    22561 actgttgcgc ctgattttaa ttcaggtata agtacttttg atttatctct atttttaaag
    22621 tttaaaatag cttctttaac tattgcttta gcatcatcaa gtgcttgttc ttctctaaat
    22681 tcaatataag ttgaacctgt tatcttagct tttggagaag ttgttacaaa tttagtatgg
    22741 taacaatctg caactctagc taatgcaggg aatatacatt gaacgtcaac tattacagct
    22801 tcaactgctc cagttattat tgcaagttct tgttgatgga agtctcctgc tatttttaca
    22861 ccatgtctca ttgtaatctc attacctgta caacacatac ctgctaagtt tattccatca
    22921 gcaccaactt ctttagctaa agctactaag tctggctctt ctgatgctaa aactatcatt
    22981 tctgataatg ctggctcatg tccatgtaat attatgttaa ctttattttc ttctaatact
    23041 gctaaattcg cctctgttct tcttggcact ggagttccaa ataagatatc gcttagacga
    23101 gtacctatca tagaaccacc ccaaccatca gccatagaag ttctaagact catgtgtatt
    23161 aaactatcta tatcaccagt acatcctata tgagtagagt gcattattgt tgcaatttct
    23221 ctatctatag ctcttggctc tatagcgtat tctttccata ttttttgtct tggttctggt
    23281 gcatttttta taaatcttaa tgtcccaaaa ggttttccaa attccattaa tgcaatttct
    23341 gccacttcat gtgctacatc atagatatct ctaccttctg tctctacatc ccattcttta
    23401 gctaaagtaa ttaacttagc ttcgtctctt attttatagt ttccatttgg atcagctaat
    23461 gctaatgtat gtgctatatc tctagcatgg tctgaatggg cagctgtccc accagcaacc
    23521 attcttgcaa agtttctacc tactatagta tgctcatctg ctccacataa cccccttgga
    23581 gtcttagggc ttattctaca tggtcccatt ccacatattc tacagcaaac accttgaaga
    23641 ccaaaaccac attgtgcctt aaagccttct tttctatcat acattgtttc tacgccttct
    23701 tctctagctt tagctatcat cttctggctg tttaaatcaa ttgttaacat tttttcatcc
    23761 atattcctat cccctttttt tgatttttaa aatcccccag gtgactgact tcatgtcata
    23821 aaataataaa ataaatgctt tctaagttga ttatatacta attttcagtg ctttgcttta
    23881 gatttaaata tttttttaac aaaattagat aatacataaa aattttattt tctacactta
    23941 atttaagttg attttatcgc ttgtttttgg ctatttgtta atatctaaac ctactttttt
    24001 gatacttcag tttaattaaa ttatgttttg atttttttaa atcaaatttg aaatttttct
    24061 agtcattttt atattattgc agattgtttg tgtatttatt atctttcact actgtttgga
    24121 cttattacag atttttactc cctaaactta attagtaaaa atttcttaga atagcatttt
    24181 ttggactaat ttttttgaat ttttttattt ttcctacttt aatattaatt atagcttcaa
    24241 attgaacatt tgtatatatt catttgaagc tataattatt ttttatataa aactttttta
    24301 atacagcatt aatttagaca ttttgactat tttttctact ttaattcatt tatttcaagc
    24361 gatttatcct atttcatatt tttagctaca atagccccat atgcaataga atataattta
    24421 gattcatgtg aatcagctct tgacactaaa actataggag cttttgcacc cataattata
    24481 cctgctgatt tagagtctgc catatatgta aaggctttcc ctattccatt accaacctct
    24541 attgttggaa ccaatatgat atctacatct ccagatactt cacttttaaa cccttttatc
    24601 tcactagctt cttttgaaac agctaaatca aaagccagag gaccttctac aattacattt
    24661 tcaccaaatt ctccttcttt acaagctttt gctaacatat ctgcatctac agttgcttgc
    24721 atcttaggat ttactttctc tttagctgcc aaacatgcaa cttttacagt ttccattcct
    24781 aaagcttttg cagcttttat agaatttttt aatatctttg ccttttgttc ataatcagga
    24841 gctatattca tacctccatc tgtagttata agtaatttat ggtatttttc taactcatat
    24901 accataacat gacttaataa actatcagtt ctaagaccat agtctttatt taacacttct
    24961 tttaatatga cagatgtatc taataatcct ttcattacaa agtcagcttc tttacttgat
    25021 actaatttaa ctgctatttc tgcacactct ttgatatcat ccttatccac tattttgata
    25081 ccacttaaat caaatcctat ttcttttgat atttctctta ttttgccttc atttccaacc
    25141 aatataggag taattatatt tctttctaca gcatccttta ttgccattaa aacttcttta
    25201 tcatgagctg ctgctacaga gagtacaatt ttctctcctc ccttaagttg ttctaaaata
    25261 tcatctaatt tttttatcaa aagtaacccc tcccttatat atatttaact aaataatacc
    25321 atatttgcta taccttttct caatttattt tttatgttat aaagaattta tataactaaa
    25381 agacagttta atattttatt ctgggatttc atcaatagct cttaaaagct ttgcaggaac
    25441 accacctaca atagtatttt ctgcaacatt ttttgttaca actgctccag cagcgataat
    25501 tgcattatct ccaatagtaa ctcctggaac tacagttaca ttagcaccaa tccatacatt
    25561 ttttcctatt gtgattggag aaggataagt tgtaccacgt ttctctggtg caataccatg
    25621 gttaagtgta gccaatacca cattatgccc aatttgcgta ttatctccaa tctcaatccc
    25681 cccctggtct tgaaaatggc aactgctatt tataaaaaca ttttttccta ttgtgatgtt
    25741 ttttccacaa tctgtataaa atggtggaaa cataaaaaat gattcatcta ccttttttcc
    25801 aattaactca gaaaataaac tacggacttc ttctggttca tgataagaag aatttaactt
    25861 acttgtgatt ttcattgcct cattactcaa cttaaccata aattcatgta tttctgattt
    25921 actagaaaca ggttttcttt gattgatatg tgttaaaaat tcattgatat tcattttata
    25981 catcctttca atatgtgctt taatttattt gtacattcta aataatattt taataaaaat
    26041 taatttaatt tatttttatt aaaatatcat tgcttctttt agtgtaatat acaattatat
    26101 ctatatcaaa tatctatatt aaatacttaa ctatacttaa aaagcatata aattgatata
    26161 attatataat aaataagtta atattgagga gggataatta tggaaataag agtattaaga
    26221 tattttttag caattgcaag agaagaaagt atatctggtg cggcaacctt tttacatata
    26281 acacaaccaa cactttctag acaaattatg gaacttgaag aagagttggg agttaaatta
    26341 ttggttcgag gaaatagaaa aatcacctta acaaatgaag gtaggctttt acataaaaga
    26401 gcagaggaaa ttatatcatt agttgataag gttgaattag aatttgacaa tcccaatgag
    26461 attattagtg gtgatatata tataggaagt ggtgaaactg aagctatgcg acttatagct
    26521 agaactgccc atcattttca tcaaaaatac cccaatgtaa gatatcacct ttttagtggg
    26581 aatgctgatg atgtgactga aaaattagac aagggactgc ttgattttgg tattttaatt
    26641 gaacctgcaa atatacagaa gtatgattat gcacaaattc ctgctactga tgtatggggt
    26701 ttactaatgc gtaaagatag tgcccttgca tcacaaagca caataaatcc aaaagattta
    26761 tgcaatatac ctcttattat ttcaagacag acacttgttg ataaagcaat ttctaaatgg
    26821 cttcaaggca gtaatgaaaa actaaacatt attgcaacat acaatttagt ttataacgct
    26881 tctcttttgg tagaagaagg tctgggctac gctctgtgtt tagatagact cgtcaatact
    26941 acagaaaaca gtaatctttg ttttagacct ctatctcctc ctttagaagc taaattaaat
    27001 attatatgga aaaaacatca aatattttca aaggcagcag aaaaattttt acttcaaata
    27061 caaaaagatt tttcttctat catgttggat acatctaagt tggatacacc taaagaaaaa
    27121 taaatcataa taaaaagtga gagtgtctca aaatgaactt tgcactgtat aaggcactct
    27181 tttttataca aagtaaaata tatgttcatc atttcagcac taaaaaagag gcttatctct
    27241 attttgagat agccccactt aaccaataaa attaaataca acttaacaat atccttactt
    27301 atttattcca agttctctta gacaagcaat cgtaatttca tcttgtggat ttaattcata
    27361 agctctttct atatagtaag ttgcatcatc aatatcacca ttatttaaat aagccattcc
    27421 taaattgcaa agtatttctg ggtcttcctt tatcttagcc gcttgttcaa aatactctat
    27481 tgctttatct aaattattct tataagcctc acaaagcccc aattccacta tagtatccac
    27541 ctgattaggc tttattatca atatcttctc aagatacatc ttagcctgct ctatttcgcc
    27601 cataccctta tatccaagtg ctatcataaa cagcaagttc caccaatcca tatgttcttc
    27661 ttctaatgga agtaacttct ctaatccttc cttaaactta ccttggaata caagtgtata
    27721 tccttcttca tattgaactt taaagtccat cttgcccaga ttctcttgta cctcagctac
    27781 taaatcagca tctaacccta gccttaacgc ttcttcccaa gtcagcttag tctttaaata
    27841 ttgaccttga ttataataat ggtagcctaa gtgataataa cctaatgcaa aattctcatc
    27901 aacatcaatt accttttcaa gcttagccat ggcttcaagt aagaatgcat tcattgcctt
    27961 atcatccata tctttttgat actgtttagc tatctcttgg caaacaatcg catagttata
    28021 cattgcatct aaatcatctg gatacattgt tataaatgct tttatatata ttaaagaatc
    28081 tgtatgttca ccaatctcaa agtattttct cgacatatat cccatatacg atttcaaatc
    28141 caaatcaata tcttttgata aagcatttaa aaacttctca tactctgcat tgtttttaaa
    28201 cttactatct attccaatta tatatatcat tgcatctgct atagacattg aatttaactt
    28261 atcttgagca gtcttttctt ttatcccttt tactaatacc tcatttttta taggtacatc
    28321 taatccacct tttggcactt catagctttt taatttaaac tctccaccat gttttatagt
    28381 tataaaagct aattcttctg ctttttttag caaatatttt tctatcttaa aatccatttt
    28441 atcctcctaa atacttaaat ctctacttta tgagttttag atttctcaaa tattttttta
    28501 tcatcatact caaataagac tacattttct acttctctta tttctgtatt tatatcattt
    28561 tttaaatcca caacattaaa tctaaatggc tcaaaatgaa catattttat tatatgttta
    28621 gctggtttat caacaaaact aggtaaatat gttgataagt tatcattatc ttgtaaaaat
    28681 acatggcatc tattcttaaa atcatccaca tctagcttat taaaaaactg tggtatattt
    28741 gatgttttac ccagtgatat atagtcatat tttaatatat cgttgaatac atcattatct
    28801 atgttgattt tttcattata gaaatccatc aatattttat ataactgatt ctttccttgt
    28861 gccaaatcaa agtagccatt ttcatcaaaa tacttggcaa aaacctcaaa gaatttaaaa
    28921 gggctttttt tataaaatct gcctataata tatctcatag ataacacaaa gtttttagaa
    28981 ttgtagtatc tctccagtat atcttctata tcctttagct tcaaagtttc ttcatagctt
    29041 atataattat tgtataaaaa ctcatatgga gcataatcct tatatttaaa accatgctca
    29101 tctgcaactt ttctcatacc tgtcccttta atcatcttta aaaagcctaa ttgcagatgc
    29161 tctataccta gattaaatac atcattaaaa gaattttcaa agctcttata atcttcataa
    29221 ggcagtcctg caattaagtc taagtgttga tgtatatttc tataagatgc tacagtttgt
    29281 acaacatgag acaacttttt aaaatcatcc cttctaccta ctgcatcaag tgttttttca
    29341 ttcgttgact gaacccctat ttcaaattga aaaagacctt ctttacaatc agccaaaaac
    29401 tcaagcatct tatcatctat caaatacgct gtaacttcaa aatgataagt tgtatatcca
    29461 ttatcatttt tcataagaaa atccatgatt tccatagcca cttttctatt tgcattgaat
    29521 gtcctatcta taaactttat ttgtgatact cttgcatcta ttaaagcttt taaatcactc
    29581 tttatcctgt ctaaactaaa ataccttaga cctggaatag tagatgataa acagtattgg
    29641 cagttaaaag ggcaacctct tgatgattca taatacacta ttctattttc atattctttt
    29701 ggattcaagt tttcataagg actaggaatc tcatccaaat cttgaagtaa ttccataggc
    29761 ttattcacta ttatctcatt gccttgtcta tatacaagtc catttacatc atttatttcc
    29821 atctttcctt gcaagtgaag tactaaatct ctaaaaatta attctccctc tccataaagt
    29881 atataatcca caaaatcata ctttttcatt gcctcataac tatcataact cacttccggt
    29941 ccgcccaaag ctattttagt attaggtcta atttttttta gattatcaca aagtttaact
    30001 atatctccca cattccagat atatgttgag aataatatta tatcatattc atttttatat
    30061 atatccttta aaatatagtc caaatcgttg tttatcgtgt attctttcat attaacttct
    30121 atcaaatctc ttacaaattc ttttagatat cttatagcca aatttgtatg aataaacttg
    30181 gaatttaatg ttgttaataa aattttcaaa tatttctcac ctctttttaa gattatactg
    30241 tctttttgta ccccttatag gttaaaatag tatatgtaaa gtctaaataa tatctatata
    30301 attaatttat taatttcaag taatgtgagg aaaggaagtt ttttatggaa ttaattgaaa
    30361 aagtatctat caactcttta tcaaaaagag atttactact tattataaag tctcttgaat
    30421 acactaatga aaatactcaa attagtgatt tcattgacct taggaataat atagtaaagg
    30481 aattatgttt tttaactgac actaaggaaa aagatttttt agattatcta gaaaaaaata
    30541 gcacactcta ataacctaaa cctttttaaa ctttaatata taaatacctg atttagaatt
    30601 tatttttatg cttaatatat tatcattaaa ggttttcgac ataactgtta tttgattaaa
    30661 tatagggtct actatagtat taccttcttc aagtcttata agacttcttg ggtctatgct
    30721 tttattatat gccttaactc caattttata ttttctcaat ttaacaacat attcggacat
    30781 agaaaaaata aaatctatat tatcttcatt taatttacta tcttcaccca aaatggataa
    30841 tatagatttt tttatgctat taattccttc attttctaca gttctatctt ccatatatac
    30901 atcatataga acatttaaaa catttaataa aatactttct tcatcataat cttcagattt
    30961 caaatcaatg tacttatcaa ttaattgtat tgctttaatc cttgccatct gaaactttac
    31021 aacatctgat ttgtctaatt ctatagaaaa tcctattatc ttgtctttaa tactctgtag
    31081 taattcgaca tactctattt tactattatt tataagattg tgcataatgg aattatacac
    31141 cacagaacct aataaataat caaataaaag ttcttctttt ttaaaataaa taacatactt
    31201 ttttattagt ttaataacct catcttcact tttttgaata ttagtatttg ataaaattag
    31261 tggtaataaa atatttaaaa aattgatatt tcctattttt tctccataaa atctatagta
    31321 aataagttca tctctcagtc tattttcgtc tatatacaca catctttgcg ttttatcatc
    31381 tattaaggat tttgtattta ttatagttaa atctttaaga gccctacttg cactactaaa
    31441 agaagatgtg tagacttttt ttagtaattc gtcattcata aatatatcct ttctgaaaaa
    31501 ttgaatgtaa ataaattgtt attaaaaaaa aagagacagc ccgtttaaga agctgtcata
    31561 tataggggga tagtagtgta caaaaatcat tgtaatctac tatctatata ttattatacg
    31621 atactacttt tttatatgta aagcatcagt tttcgacatc cctatatttt acagttatac
    31681 aaattgcgta ctaagttcaa ttttattctt tttatttcaa cattttatca tgctacattc
    31741 tttcaggagc gtgcattccc aacaatttca gagaattttc taaagtttgt tttgttgcta
    31801 aaactaatgc aagtcttgct tttcttattt ccaaattttc tactaaaatt ggattgtcat
    31861 gataaaattt attaaacgct tgagctaaat ctagcataaa tctagtcact atatgtggct
    31921 catttttctt tagagcaagt aaaatattct tattgaatga ttctataact ctaagaactt
    31981 ctgcactatc ttcatcagct aatagactat aatctatatc agaagtcact tctacttctg
    32041 cttttcttaa aactgcacag catctagcat gtgtatactg aacatatggt ccagtctcac
    32101 catcaaaact aagcgttctt tcccaagaga aggtatagtc tttaattcta ctattagata
    32161 actcttggaa tactactgcc ccaacaccta cttgcttaga tatttcatcc acatttttag
    32221 catttgggtt tttagctagt ataatttcct tagttttatc tatagcttga tttaaagcat
    32281 cttctaaaaa tactactctt ccttttctag tcgacatagt accttcttca agtgcaacca
    32341 taccaaatcc aacatgaatt aaatcttttg cccaatcata tcccataagc tcaattacct
    32401 taaaccattg ttggaaatgt aagttttgtt gagaaccaac tacatatata cacttgtcaa
    32461 aatcataagt ttcttttcta tatattgcag cagctaaatc tcttgtcata tataacgttg
    32521 aaccatcatt cttagtaata agtgctggtg gcattttata ctcttctaaa tcaacaattc
    32581 ttgctccttt agactctttt aaaagatttt tctcttctaa tagttcgata actctgttca
    32641 ttttatcaga ataaaaactc tctcctgcta aagaatcaaa ttctatatct aaaagtttat
    32701 aaactctgtt aaactctttt aaactctcat ttctaaacca ttgccataat tcttgtgctt
    32761 cttcgtcacc attttctaat ttattaaacc atgctcttgc ttcatcttcc atttctgggt
    32821 gttgttcagc ttcatcatgg aatcttacgt ataattttag taattctgga attggattag
    32881 actctactac ttctttttct ccccactttt taaaggccac tattaactta ccaaactgag
    32941 ttccatagtc acctaaatga tttattctta tagtcttgta tccttgcgaa tcatatatct
    33001 tatataaagc attacctata actgtagttc ttatgtgccc tatatggaaa ggttttgcta
    33061 tatttggaga agaatattca actattacag ttttatcttt tccaaaatca ctatgtccgt
    33121 aattttcttt ttcatctaaa acttttttaa ttacagtttc tgctaattga gatttattta
    33181 caaagaaatt tacatatccg cctaattgta ttacttttgt tatctctcca cttggttcta
    33241 tactttccgc caattcactt gctatcatgt ttggagcttt tctaaacact ttggctaatt
    33301 taaagcatgg aaaagcatag tcccccatat ccttatttgg tggaacttct ataagtgcct
    33361 ctatctcttc tttcgataaa tcttctattt tttctttaag gcaatttgat attgccacct
    33421 taaaatcttg cattctgttg ctcctctcta cattgttcct ggtttatatt gtgcttatct
    33481 ctttatgtta aatcaaattt cgtgtttttt caagtatttc attacagtgt aaaacacttt
    33541 agtaattatg ttttctgtat atattaaaaa tactataatt tcagttttta atcacactat
    33601 tattgatttt ttataagact tttttctatt ttattgtttc ttgtactatc cagttgactt
    33661 tatatacttt ttttaatctt ttatctgttt tcatacatca atgtcagctt tatatacatt
    33721 tttttaatct tttatctatt ttcatacatc aatgtcagct ttatatactt tttttacttt
    33781 tttatctatt tttatacatc aatattagct ttatatactt tttttactct tttatctatt
    33841 ttctataaat ctttttcact cttaactttt attccttctt cttctaatag ccttgctgtt
    33901 atacctttcc ctggtatctt tttacctgaa aaactaccat catatattag attacatcca
    33961 caagaggggc taccctcttt tagtattgct tcgctacata catataaatt tgctattttt
    34021 agagtttcat tagcccctct tacaaagttt tctgttacat ccttattatc tttagtaatt
    34081 acttttccat caactatctc agcaggtggt cttggtgtag atagaccacc taactgctct
    34141 gggcatacaa gtgtaaattc tttgcctttt aaatattcct tgactttttc attatcatta
    34201 ttatcgccac tatatttaca atttattcct attaaacatg cagataccaa tatcataaaa
    34261 atgtgctcct atacaaatta tatatattct catacaaatt actaatgtat tcttatacaa
    34321 attattttaa tttaacaatt gttactcctg ctccaccttc tccatattga ccacctcttt
    34381 gtgattttac atgtctattt cttcttaaaa tgtcttgtag ccctgctttt aatactcctg
    34441 tacctattcc atgtattact gttacagact ctaaacctgc cacatatgca tcatcaagat
    34501 acttttctac ttccattata gcttcttcta ggtttaaccc tctaaggtca acttcatttt
    34561 ttacactacc agattttgac cttataatgt ttctcgttga tttagttaca tttgttgaaa
    34621 catctttgcg tgttttttgt aaagatttaa aaggtagagt catcttcatt ataccaattt
    34681 gcactactgc ttcttttctc tttttatcta ctgaaactac actaccattt tgatttaaag
    34741 ttattacctt aacttcttca cctggcttta agtcttttat ctccttattt gatacctttg
    34801 gaactatcat actttttact gttggctgaa gacttcccat agagctagtc aattcttttc
    34861 taagttcttc tatcttacga ttcttttctt ttgaagctct ttcttgttca agacttctaa
    34921 gttcttttat tataatatct acttcttctt tagcttgtct tataattgaa aatgcttctg
    34981 atttagcttt ttcaatcatc ttatctcttt gactgaccaa tttttcaagt ttttcgtcat
    35041 actctacttt cagtttttca atctcttctt ttaatctttc agcttcttct ctatcttcta
    35101 ctgctttgat tctattcttt tcaacattct gtaacacatc ttctaaagct atgttttctg
    35161 tatttatata ttctttagca cgtgaaatca cataatcact tagcccaagt tttctagaaa
    35221 tctcaaacgc atttgatttt ccgggaacac ctataagtaa cttatatgtt gggcttaaag
    35281 tttctatatc aaattcaact gctgcgtttt ctacacctgg tttagtaaga gcataatttt
    35341 taagctcact atagtgagtg gtagctatac atttagctcc tacagaattt atatcttcta
    35401 atactgctat tgcaagggca gctccttcaa cagggtctgt tcctgctcct aactcgtcaa
    35461 atataactaa agagtctgct gttacgtttt gtaatataga tactatattc gtcatatgag
    35521 atgaaaatgt tgatagactc tgttcaatac tctgctcatc tcctatatct gcaaatacat
    35581 tatcatatac acacatacta cttccataat cagcaggtat atgaagtcca ctttgtgtca
    35641 taagtgcaaa tagacctaca gtttttattg taacagtctt accacctgtg tttggacctg
    35701 ttatcaccaa tgtatggaag tctcttccta aataaatggt atttgctact accttctttt
    35761 tatccagcag tggatgtctt ccatttttta tgtttaaata tttatcctca tttaaagttg
    35821 gttctattcc tctcatctgt atagaaagtt ttccctttga aaatgcaaag tccaatcttc
    35881 caagtatctc ttgattagag attaaatctt cgctcacttc tccaaccata gcagaaagct
    35941 ctgataaaat tctttctatt tcttcttgct cacctagttt taactgtctc aattcattgt
    36001 tcatctctac tatagtcatt ggctctataa aaagtgtcgc accagaagat gactggtcat
    36061 gcactatacc agctacttgc gacctatatt cagattttac aggtactaca aatctatcac
    36121 ctcttagaga aattattgca tcttgtaagt acttttgata agtagttgaa cttattattg
    36181 aatttaattt tgacctaatg gattgatttt tttgggctat tcttcttctg atatctctaa
    36241 gtgtacttga agcattgtca gatatttcta cttcactaat tatagcattg tatatctggt
    36301 cttctatgtc cttgtataca tatagagaat ttgatagaga ttgtattatt ggataattaa
    36361 aatcttcttc atcactacta gataagctat ttcttaatct tctagccact cttaaggtat
    36421 ctgctatcat aatcagactt cctgggtcaa gagaagcacc tatataagct ctctttacct
    36481 tatcttctat atcatgaata ccttccaacc ctactgaacc tctctttata ataattgatt
    36541 gagcttcact agtttcttct agcatagatt tcacttctac aaaatcagta tttggtacta
    36601 aattttctat atattttaga cctaaagaag atgaggcttt cttctttaac aaatctatta
    36661 ttttattgta ttctagaact cttaacgatt tctcattcat tttctatatt caccatcctc
    36721 gatattttaa cttttttatt taattttaaa aatgtatgtt ttcaagcatt tccaataaaa
    36781 actgcaagtt ttatttcttt ttcatttcta aaattattat attttttctc ttttagatat
    36841 attttacaca tattttgtat tatactatgt atgtagctat ctatatatta tacataaaca
    36901 tgctttattt gtaatataat ctgttaaaaa atcttcttta atatttttaa aggagtttat
    36961 tttagcttat aaaaaaaaat agctacttat atagataaat taaggaggaa catgagtcat
    37021 gggaaacgta ttagaaggat taaaaccaga aagtgttttt aaaaactttg agaaaatatc
    37081 tcaaattcct agaggttctg gaaatgaaaa aggcataagt gattttttac ttagctttgg
    37141 taaaaattta ggtcttgaaa ctattcagga tgaaagctta aacataataa taagaaagcc
    37201 tgctacaaaa ggatatgaaa attgtccagg tgtagttctt caaggacata tggatatggt
    37261 ttgcgaaaaa gaaaagaatg ttgaacatga ttttcttaaa gaccctataa aattaagaat
    37321 tgatggtgac atgatatatg ctactggaac tactctagga gctgacaatg gtatagctgt
    37381 tgctatgggt atggctatat tagaagataa tactttagag catcctgcac tagaagtttt
    37441 agttactgtt aatgaagaag atggtatgaa tggtgcagat gcactagacc ctagcttaat
    37501 taaaggtcaa tatatcctaa atatggactc cgaggaggaa ggatacttat tagttagctg
    37561 tgctggtggt aaaacttgtg ttgttagttt acctgttgaa tacaaggaag ttaaaggtga
    37621 caaacaagga ttattagttg aggttactgg actattaggt ggacactctg gtatggaaat
    37681 tgttttacaa agagcaaatg ctaacaaagc aatagctaga gtattaagtg tattgaatgt
    37741 tgattatgaa ttagcttctg ttgatggtgg tactaagcac aatgctatac ctcgtgaagc
    37801 taaatgtgta atagctgtta ataaagctga tgttgaatct gctaaaaaac aaataaatga
    37861 cattttaact gcatttaaac atgagtttac tacttctgac cctggcatga cttactcagt
    37921 agctgaaact tctgtagaca aagttcttac taaagattgt aaagaaaaag ttgttcaaat
    37981 gtcttgctta actcctcatg gagttcaatc agtaagtctt gatatagaag gattagttga
    38041 aagttctact aacttcgcta taatcgaaac taaagaatct actattgaat ttttaacttc
    38101 tgttagaagt tctgttatgt ctattagaga tgaaatcgct gatagaataa gacttttggc
    38161 tcaagcttta ggtgctaatt acgaccttat agctcaatac ccagcttggg aatttaaaaa
    38221 aggctcaaaa ttagaaaaaa tatgcagtga aacttatgag aaattaactg gtaaagttcc
    38281 tactgttatg gctctacatg ctggtcttga gtgtggatta ttacttgata aacttcctca
    38341 tgctgaagct atctctatag gaccagatat gtttgatgtt catactccaa atgaacatgt
    38401 tagtatccct tctgtagcta atgtttggga ttatgttatt gaaatattaa aatctatgaa
    38461 ccaatattaa atttaagttt tgattctaag tagattttaa ttttaagtaa tctatataaa
    38521 attaactctg taaattaata ctacggttag tataatattt actttcaata ttaacttata
    38581 gaaataaagc ctaatgatag ataataacat gtatcattag gctttattgt aatttaaata
    38641 ttattaagct ttattctgtt ttaaaattaa ttcttatact attttaaatc tatttcttcc
    38701 ttgtctctta gaatcataaa gagcattatc tgctatttga tacagttcat catactcttg
    38761 accaggcttt gctataacta cccccatact aatagataaa ctttctccat ttggcaactt
    38821 aatgagatga atatgattgt atacatcatt acatttatta ataagttctt ccttatttat
    38881 tatatcattg atataaacac taaattcatc tccacccaaa cgacctacta tatcattttt
    38941 tgcaaaactt tcatcaagtg cctttgcaac atcaataagt actttatctc ctaacaagtg
    39001 accataagta tcattaatcg atttaaaata atcaatatct ataatcaata aagcaccatt
    39061 tttttcagtt gataaattca acaaattttg tgaagttaat tttctaatat atgctgcatt
    39121 ataaatattg gttaaactat ccctttgagc cttatctaac aatctattct tttcctcttt
    39181 ttcagaatca atattacata ttttcccgat tacatacatt ggtatttttc tatcattata
    39241 aattattttt gaagtaactc taatccaatg aaaagtatca tcaagcataa tagaatacat
    39301 ttcagttgtt ccattttctt gtgattttat tacatcaaaa aactttttat tatattcttt
    39361 ccttatttta tctctttcat tttctatatt gccattttca ctttccttat catttttatc
    39421 caaaccataa taagtctcaa tacccttttc tggcatagaa attatcaatt tatcttgctt
    39481 ataatcatac tcaaaaaagt attcacttgt catttcatac aactgagtat gttttttgag
    39541 ttctaaagat atcttctcgt tcatacttgt acgagtatgt aaaccaaatg ccataaatcc
    39601 aataatacaa attaataaac tggctacaat aaaaatagtc tcaattggat tctgttgcat
    39661 aatataaagc aacgagaaat cttgtctata tgtagtattt tggtagacaa ttgattgcat
    39721 tttttctgat gaaatactta taatagcttt attaaatata ttcaataatt cttgtttatc
    39781 ttttttaatt ataccaaaac aaatactctt tgctttatag gtttgaggaa ctagacgcac
    39841 atttttatac ttaggttgat tcatatagta ctgcatagaa taaccttcgc cataagtgta
    39901 atctgcatag cctttattaa cagcttctat acactcttct aaattatcat accaaactat
    39961 attctcttca aactgaccat aataattaat acctttggct agagctacac gttttccatc
    40021 taaactattc tcatttaatt tattattaat catcatagta tattgagtag aaagaaaagg
    40081 ccgagacata gctatattat gttcacgaga gtattcataa tcataaatca ttcctgctac
    40141 aatatcaatt tcacgctttt tagtcatgtt ttctaaatct tcttgagatt ttacaggcac
    40201 aagttcaaat tctaagcctg ttttatcaca tatatgattt aacaaatcaa ttgatatacc
    40261 tcttaattca cctgtatctt tatctatatt ttgaaatggt ggtttgttta aaagtactcc
    40321 tacttttaat ttttctgtct ctttaatgta attagtttct tcatcagata aaaacatttg
    40381 attattctct ggtgtaaagt atttttcata taaagtagtt gaaaaatatg ggtctttctg
    40441 ttcaatatta ttaattgctg agttaagctt ttgagttaaa tttgtactac ctttaggagt
    40501 aatgaaataa aatggttttg atgaaaattt tgctacagta cgtacacctt ctattgggtt
    40561 catactcaca ttaagaagta catctgcttt accactcttt agtgcttcta gttgctcatc
    40621 atttgtttta caatatacca attcaggtga cataagattc attttacaat actcatctaa
    40681 ttctttaagt ctagtatcag aattttctat tacagcaata cggatttttt tcacatcttg
    40741 tgaactcatt atgttatcaa tatctgtatt ttcatataat gcttgtagta ctgtatttgc
    40801 tactccataa ttattccctg cataattata tattttttgc attggttcat tgtataacat
    40861 acctcccatt atatcaattt caccattttc taacatcttc attaattttg taatagattc
    40921 atttatctct ccaggaactt gaacaaattc ataattccat ccagtatact gtgcaatttc
    40981 tagtaaatat tcatatgtat acccaaaata gttaccttgc tcatctattt cagttaaacc
    41041 tttttgaata ggataagcaa cacgaatggt acgattatca ttacctatag cgttgatacc
    41101 aaaagaaaat atgcaagaag tgaatataga tgtaattaca ataattaata aaagtaattt
    41161 ttttaaattc actacacaat cctccatata gttaagattt acagtataaa ttactgcata
    41221 aacttgtaga catgtaaaaa tagattagta tataaaagga tatataaatc tacttagaaa
    41281 tttaaatatc cttaatatat acaatatatt taaattataa ctcatttata tgtctattac
    41341 aacaaattta ccctgctaaa tacctactct atatcccata attttacaag ttgtagtgaa
    41401 gtttaagttc tatctcacct caaatttagc agtgtttcta tttacagttc ttttatattt
    41461 cacatctgga taacccaata taaatgaagt gataactgct tcgttctcgc tcattcctaa
    41521 cagttctttt atctttggct ctacatttga tgccataaca aaaaatccat tataacaaat
    41581 tcctaatcct tgagaatagg ccataagttc catattagat gcagccaatc ctccatctac
    41641 ataagcactt ccacctagag acatatcacc tacaactacc ataagtagtg gggcatcata
    41701 aaataaagaa tcatttccgt tctctttgta tcttttgtac attttcttaa atgtattttt
    41761 atagatagaa cgtacagggt cattgtcatc agtatctaat gccaaattat aaagaccttg
    41821 tattgccagt tctttcactt cttttagctt ttcttttact aatatgtatc ttataggctg
    41881 tctattacca cctgttggtg tgtatctacc agcttccact atgtttttta ttttttcttc
    41941 ttctacctct atatctttat attgtcttat acttcttcta aatttaataa aattcaataa
    42001 cttttcgggt tctaattcaa aactttcacg attgtattct attacttcat ttttatcaaa
    42061 tccttgcatt tctattgcat ctgttgggca aattgccata cagtgaccac agttaataca
    42121 gagaatattt ttaacctttg ctttatcatc cttaactttt attgcattta caagacagtc
    42181 tgattcacac atcccacagc ctacacattt ttctaaattt atgtctatca ttccaaatta
    42241 ttcctccttt taaaaaattt actttagtat aaaacaaata gttgtctaag tcaattttta
    42301 tttttttaac aatatactag ccttaactac actttaatgg agaaaaatat acataaattg
    42361 gaacttaaat tagaacttat tcaaagtaaa agataaaaga agtagatgtc taaaagtgaa
    42421 ctttttagtt aattagatat tctttattgt atgaaatcaa gtggatattt atcatttcaa
    42481 caataaaaaa ggcttacctc tattttggat atgtccctgt caagtagaca gactaaaaaa
    42541 aggctatctt tatgcactga gatagcccct tttcccaact actattgttt atcttaatat
    42601 tagtcaataa atttaatttg ctataacctg taagttacat tttaatttga tgtaacttta
    42661 aattacattt ttaagtaata tctttaaatt atattcttaa aatatatcat taaactacat
    42721 tttaattaat ctaaaaacta tatcttaatt aatctaagaa acttacatta taatctttta
    42781 gtttcccatt atcatataca atctttgcac taaagatatt tccagtctta gcccaattta
    42841 agaacagcct gtcaccttcc cacatattta aatcgaatat tttatcatta tcaacccaaa
    42901 ttaaatttcc ttctttacaa tcatttaaat ctttttcaga taattcacct tcaaactcat
    42961 ctgagaaata caaaaacata taccaatctt cttcatcttt aaattttgga aaagttatca
    43021 accctttata tgacaatgat ttaagagtaa gaccagtctc ttcttttact tctctaatta
    43081 cacattcttc tggagtctct ccttgctcaa actttcctcc aactcctaca tacttacctt
    43141 catgtatatc atctttcttt ttatttctgt acaacatcaa agtcttgtca tctttttcta
    43201 tataacaaat agttgtaagt ttcatgtatc tcgccttgct ttctctttta tattctcaac
    43261 taattatttt cagcactttc aagcacatca cttatattct tcattgcatt aagagaaagc
    43321 tctgcaaatt catcaaatgg aatccctata tcttctatac ttctcattgc atctctattt
    43381 acatttgaag caaatctcgt ttctttcatt cttttaataa cagacttagt ctttacactg
    43441 gtaagttttt tatctggata aactaaagct atagcagtta taaacccagt tatagggtct
    43501 gctgcatata ttgctttttc cattaggcta gttcttgtaa ctcccattcc atcatgatga
    43561 ccaagtattg ctctatacat ttcttcgtta ccgaagtttt cttttttaag cagttctact
    43621 gttgttgtag catgtccttc acatatttct cctggctttc ttccaactat atctgaatcc
    43681 aaatcatgta aaagacctgc cactgcccac tcttcttctt tttctggctc tagtcttttg
    43741 gctaattctc tcataacagc ttcaacagca taacaatgtt ttctcattct atcagtttct
    43801 aaatacttaa ataaaatttc taaagcttct tctctcattt tcaccaatcc ccctgttttt
    43861 tcacatatat gatattttta tatattaata cacataaatt caagctttta tatatattca
    43921 tgtatatttt tcatgttata tctattctac acctttatag tagtgtcctg caactgttcc
    43981 aatttcatct aatttcttat acaagtctgt agcctttttt ccaagtttat aattattact
    44041 cagtacctca atgtgagctt caataacctt tttaaccatc tcactatctt caactgtaaa
    44101 atctatccta aatacatcta ttccaatttc ctctaactca tatagattgt ccaacataca
    44161 agtaaccttc gaattgtaaa ttgtacttct acagaatata tcttgtgtta tcctataact
    44221 tgcatccgta aagtctctta aagcataact actttcctta catttagcaa ctctcttgtc
    44281 ctttttacaa tctctaacaa ctactcccat aggacagtat tctgtaacca tcataggagc
    44341 atatccatat attactgctt caatttctac atctgtatat tttaaagttt gtttaatttc
    44401 atttaagttt agttcttgtg acaaacaaac tgtacttgct ccctcttctt tgaagtgatt
    44461 tatactttca ctattgaata catttaagta gcaatctata tttaagtctt ttttcttaaa
    44521 gtattccata gagccccagt taccaatttg aaccttatta attcctttta tattatccaa
    44581 tatctcaaat tgcttgtact ctttatttct aacaatcctt ggtgctgaat agattaattt
    44641 tttgtcagtg actgctgtat tagagtggtt cttattcaaa gtatctattt tacttgtatt
    44701 tgacaaagta tctatgttat ttgtatttga acccattagt tctttaggag tacctaaaga
    44761 cgaagaagta tctaaatcca tagaaatact tgaatctata gaaatatttg aatctataga
    44821 gatacttgag accatttgta aagcttttga taatgtattt atatcttcat aatagattaa
    44881 atctacatta taatttaata ctgcttctaa ttgctccaag ttcttaactt taactctaat
    44941 cttaggagct gtatcaagtt ttttctgttt atttactcta tttggctggt attttaatct
    45001 attcttctta aattttctat cttttatctt tattctttct tcatctaaaa gctcaataca
    45061 atcccttctc atttgattta acacacttat aggcatactt acaccttcat ccaggtcaat
    45121 ttctatctct tttaacttat atggtgtatt tccaagcttt tgaatttgtg tttctatttt
    45181 ttctttactt aaagccacct ttatagcttt ttcaactatt ttgtctcctt ctaccaccga
    45241 tttatttcca caaaaatcac ttataaaaag ctctggcttt ttacctagtt taatactcac
    45301 ttttgcacgt atattagttt ttatgaactc tttatcttgc tgaaatgtag cttgtactct
    45361 atccattaat tcgctgtcag aagtcttata tataagctga tttctctttg cttctccaac
    45421 aaaatctaat tctatcaaat cccctttatg tgctattgta gttatctctc catcctttat
    45481 tattcttcca atagtacctc cacctaagtt aattccatca cctttcttaa gcgtattttc
    45541 tagcattact ctaagtcttt tgttctttct attataatct aaaacttttc caatatatag
    45601 cccttgatta ttaggtctat tagagttcat tatatcctta ccaacttcac ctaatatata
    45661 tccttttgta aactttctat taaatatggt atacaaatta tttattattt cctcagaaat
    45721 acttattttt ttcttatcta caaattcatt aatcgcttct ctatatcctg aaaccacagt
    45781 agctacatac tctggctttt tcattctacc ttcaattttt aaagataata cacctgcttc
    45841 aattatttta tccaaatctt ctatagtact taaatctcta ggactcaaca aataatctcc
    45901 attacttttt actacttctc ctgtatttat atctatcaac tcatactttt gtctacatgg
    45961 ctgtgcacac ctacctctat ttccagacct attgcctatc atactactca taaggcattg
    46021 acccgagtaa catacacata aagctccatg tacaaaaact tctatatcta cagttgtatt
    46081 ttcacaaatc cattttatct catcaacatt taattctctt gctaaaacaa ctctatcaaa
    46141 ccctacactc tgaaggtatt ttacatcttc taaggaatgt gctaccattt gagtgcttgc
    46201 atgtagttca aagtcaggta atagtttttt tataagtctt gccattccta tatcctgtac
    46261 tattaaagca tcaatatcta tatcgtataa aaattttaca tactctacaa aatcttctat
    46321 ttcatactgt tttatcaatg tatttacagt aacaaagact tgcactcccc ttatatgaga
    46381 gtatttaaca gcctcaatca gctcatttct atcaaagtta tttgcagatg ctctagcact
    46441 aaagtcttta ccacctaaat acacagcatt tgctccgttt tgaactgctg cttttaatga
    46501 atcaaaagag cctactggtg caagtaattc tatttttttc atatttttct cctctattta
    46561 tacttgttag gttaatataa ttatatctat aacttaaata tttgtattaa atttatatat
    46621 ttcttactat attttaaatt cttcaatcaa tttatatatt agttatttat atttggttca
    46681 tttgagttaa catatacatt atttactata tttagtatat ttctattaac ttatatattg
    46741 attactgtat tttaaattct tcaattaatt tatatactgc ttactaaatt taaaacattt
    46801 taattaattt gtacactgtt tactatactt gaaatacttc tattaatcta tatattgcct
    46861 actatactta agacatttta attaatttat acactgttta ctatacttga aatacttcta
    46921 ttaatctata tattgcctac tatacttaag acattttaat taatttatac actgcttact
    46981 atacttaaaa tacttctatt aacttataca ttgcttacta tattttaaat tctttaatta
    47041 atctatgcaa tatttgctat atataaagta tatcaaataa cagcttcatt tttttgtaaa
    47101 tttacagaaa gttaattttc attaaatgaa tcatctttat tgataaacat aattccaaag
    47161 accactgcca aaataaaaaa acatattagt attgattttt ccacgaaaat ttttgtaaaa
    47221 aaagttccta aaatagctcc agatataaag aatataataa cagcataata ctgtaaactc
    47281 ttttttatca taaaaatatt cttagtatgt atataatgaa ataaagtttc tgtagcactt
    47341 cttaaatttc cagtacacat tgtcgttgca aaactattcc catttacttt tctaaaactc
    47401 tctacttgca ttgaacaaat aaaagaaata gcaacattta caaacatatt aaatcttcct
    47461 ctaggaataa atgaaacaat aagtattgta atcatttcaa ttataatgat aacctgacgc
    47521 caatgaatct ttgtcttatt atttgtaaaa tactttctta tcttctcggc tataaataca
    47581 cctaacataa atgccaaaat aggaatcaaa taataaaatg attcctttac attaccttct
    47641 gctatattaa gcccaaacaa aactatattt ccagtttgtg cattagcaaa gactttacct
    47701 cttaccacat aagtataaat atccaaaaat cctcctgtta ttgccaacaa agaacataaa
    47761 aagaatgatt cagacatctg actcttgctt gtcatatata aacctctcgc tttctaatga
    47821 tagatacaaa atcaaaatca ttttagattc tatttttcat tgatataaaa aaattattta
    47881 tatttaaata ttgtctatat ttatacatca tttatattta tacattaaaa gaagctgtct
    47941 caaaaaacaa gagacagcaa atcttttagt ttattccaca ttttttgcat cattatttaa
    48001 ccctgtacat tttaactgta aatcataagc tttgttttga aactcagaag ctaagttttc
    48061 agctatagta gctctttcat ttgcttcttc aagttgagta cttaactcct caatcttgtt
    48121 tttataagca tctaactctg ctctagaacc ttctgtcgta ttactaagtt cgaatatttc
    48181 ttgcttttta ttttctataa tctcaattaa ctctttcatc ttagtttcag cttcacgatt
    48241 ttctgcttct ttttctgcta tcgtaagctt taaagacttg atttctaatt gaagctcttc
    48301 attagatgct ccaaccttct tactcaattc ttcattagct ttaatcaact tctcattctc
    48361 atctgaacat tcaaataaaa ggtctgatat atttaatgca gttaatatcg cagcaactga
    48421 taagctcaat ttcgggtttt gacgtgttat tttatccatt tctttgtcta caaaatcagc
    48481 aatactaatc ataaacttct ctgatttgtc tccaaccatt ggatattcag cgccatggat
    48541 tttaaccatt actttgttca tcctaacctc ccccgacatt agttgttaat ttgatcttaa
    48601 gttagcattt aatttttcgc ttaattcact taatatctta tcatgcacct tagctacatc
    48661 ttcatctgtt agagttttat ctttacttct ataagttatt gaatatgcaa ttgacttgta
    48721 tccagcttct atttgagaac ctttgtaaac atcaaataac ttgtagcttt ctactaatcc
    48781 ttgaccattt tcctttatta tatcttctat ttgttttaca aatacatcat ctttaacaat
    48841 aagagctata tctcttgatg tagatggata ttttggtaat ggcacataat tctttgttct
    48901 atcagaatta tcaaatacaa agtcaatatc tatttcagcg acataaactc tttgacctag
    48961 attgtagttt tctataacat ctggatgcaa ttcacctaat gtacctacat atttattatt
    49021 atacactatt ttagcacatc taccagggtg gaaggtagta ttattatctt gaggttcaat
    49081 ttcataacct ttaaatccga catttacaag tatagtttct atagttcctt ttagtgcaaa
    49141 gaagtcaaca tctttaccat acatacctac acacattcta ttttcttcct taggtaattc
    49201 tgaatcttgt gggatgaata tatgtccaca ctcaaatgca gatacttctt ctattttatg
    49261 agatacatta gttgataaaa catctaacat atttggtatt aaagtagttc tcattacaga
    49321 agtttcttct cctaatgggt taagtaattt aacaaaattt ctctttgcat taccttctgg
    49381 tactcttatc ttatctactc ccttagggct tacaaatgaa tatgttaata tttcatttaa
    49441 tcctacagca gttgaattat cttttaaagc atccatgaat ttttgttttg aagttttaat
    49501 tcctgctgtc gtatttcctt ctaattgtac agaaggtata ttctcaaatc cataaattct
    49561 agctatttct tcccatacat cagcttcttg ttccatatct gttctaaagc ttggtacatc
    49621 tatttctaat ttatcattag ctaccaaatt acatttaaac tctaatgatt ctaaaattcc
    49681 tacaaactgc tccattggta catctacacc taatagatgg ttaattcttt gaggatttac
    49741 taccaatttt ttaggttctg gtttatttgg atatacatct acaacacctt ttaaaacttt
    49801 tcctgctcct aacatttcaa caagctgtgc agctctattt gctgctatct ctgcaagatt
    49861 agggtctaag tctttttcat ttcttgaaga tgcttctgac ctaataccaa cttttttagc
    49921 tgtcattctt atgttttctg gtttgaaatt ggcactttca aaaagtacag tcttcgtatt
    49981 agaagttatt tctgagttag caccacccat tacaccagct aaaccaagtg atttttctcc
    50041 atttgttata actagcatat ctttgtctaa tgttctctca acatcatcta atgttacaag
    50101 tttctctcca tctttagcat ttcttactac tattcttcca gtctctactt gatttatatc
    50161 aaaagcatga agtggttgac caagctctaa cattacgaag tttgttatat cgactatgtt
    50221 acttataggt cttactcctg cttctgtaag tcttctttgc atccaatatg gagaaggttc
    50281 tatttttaca tctgtaacca ttctagcaac atatcttcta cataaatctg gattatctat
    50341 ctcaactttg aaatctatct cttcgtcact ttcttttact tcgatttcag gatattttac
    50401 ttttgttcct atagttgcag ctgcttctct agctataccc atcatgcatt tacaatcagg
    50461 tctgtttgaa gttaattcaa aatctattaa agcatctttt aatcctaaaa catcttttat
    50521 atcttttcct aattcataag aatcttcgtg gtctaaaata tatataccac ctcttttata
    50581 ctcctcaatg taatgttcat ctatacctag ttcagctgct gaacacatca taccatctga
    50641 taattcacct ctgaaatcag tctgtttgat ttcaactcct ccaggtaact tagaaccatt
    50701 tacagctact ggaatataat ctccttctga tatatttgta gctcctgtaa ctatttgaac
    50761 aactttatct ccaatatcta ctttggttac aaccaactta tcagcatttg gatgttgttt
    50821 tatttctaaa atctttccaa ccaatatatt ttctatttct tcaccataat aatctattgt
    50881 ttcaacttta gttcctgtca ttgtcatttt atcagcgaac tcttttacat ccatgtctat
    50941 atcaacatag tctctaagcc attttaaaga tactaacatc tacataccct cctaattaaa
    51001 attgatttaa gaatctcata tcattttcga ataataatct aatatcatct atttcgtatt
    51061 taagcattgc aagtctttca accccaactc caaatgcaaa tccactgtaa acttctgggt
    51121 ctattccaca atttctaagc acatttggat gaaccatacc tgaacctaat atttctatcc
    51181 aaccttcata tttacacatt gggcaacctt taccaccaca tttgaaacaa gtaacatcaa
    51241 cctctgcact tggttctgta aatgggaagt tgtgaggtct aaacttagtt ttgatatcag
    51301 aaccaaacaa tttttcaacg aagatatcca tagttccttt aaattctgcc atagtaacat
    51361 cttttccaac aacaagccct tctatctgat ggaacattgg tgagtgtgta gcatctggcg
    51421 agtctgacct aaaacatcta cctggtgcaa ttacttttat tggtaactct tgacttctca
    51481 tagttcttac ttgaactgga gatgtttgag ttctaagtaa taccccatca ttgatataga
    51541 atgtatcgct catatctctt gatggatggt ctttaggagc gtttaatgcg tcaaagttgt
    51601 tttcaacagt ctcaacttct ggcccttctg ctatagagaa tcccattccg ataaatatat
    51661 ctgttacttc atctataatt tgagttattg gatgcttctt cccaaccttt aaaacttttc
    51721 ctggttgagt aacatctatc acttcctctt ttaattttct ttctttttca atagcattta
    51781 tttcttcttt tttagaattt atgctaagtt caatgttttc tcttacctca ttggcaacct
    51841 taccaactac tggtctttct tcagcagata atttacccat ttctttaagt atggcagtta
    51901 tctcaccttt ttttcctaag tacttaactc ttaaactttc tacactttct atgctttgtg
    51961 cttcttttat ttcagccaaa gctgcttcac gtaaagcaag taatttttct tgcacacata
    52021 tcaccctttc gtttttttgt ataaaaaaag cccctcaatc cctgtctagg gacgaaaggc
    52081 tatagtttcg cggtaccacc ctagtagttt aacaatttaa aaatcatcaa accacctcta
    52141 acaaacttaa cgcgtttttg acgtcaaagc ctactgtaaa atttcagctc tgttactcca
    52201 gagggaactt ctcatgacct cttagaaaac actcccagcc taggtgttta tctctttact
    52261 aagtttaatc aaaatacttt cctctttcat tgcatttaca atattatatt gtttatttta
    52321 gtattatatc atttccattc aaattatgtg actattttta atatatatcc aatacataat
    52381 taatttaatt attttttata taatatacat ctaatgcata attaactcaa ttatttttta
    52441 tataatatac atctaatgca taattaactc aattattttt tatataatat acatctaatg
    52501 cataattaac tcaattattt tttatataat atacatctaa tgcataacta actcaattat
    52561 tttttatata atatacatct aatatataat taatttaatt atttttttaa tatatattga
    52621 ctatttttga tactctacta tttaattcaa gattataaca tgacattata tttattacaa
    52681 tacattaaat taagtatttt tttatttcat acatcagtat agcagagctt atcgcagcat
    52741 ttaacgactc ggctttacca tatataggta tcttaaccaa aatatcagac tttgatacaa
    52801 gttcttcatt tattccattt gcttcgtttc ctatcaccaa tgctactttt gagccataat
    52861 ctattttgtc ataaaaattt tctgtattta agtaacttga aactatatta aaatccaatg
    52921 atttaagcat gtccacagtt tcatcttgtg aagcatcaat tatattcaca tcaaaaatag
    52981 aacccatagt agacctaatt acttttgggt tgtatatatc gacacatccc tttagtgcta
    53041 ttatggcatc tactccagca gaatcagcag tccttattat agtccccata tttcctgggt
    53101 cttgtattct gtctaaaatc aatacaaatt tatctttttt atttatactt tcacttaatt
    53161 tttttttctt aaatgaaact acacctatta ttccttgagt attttctgta tccactaatt
    53221 ctttaaagtt tttattagta gtcttgtata tctttgtgtt ttttttatcc aaatcttcta
    53281 atagttttac atgttctttc ttattttcaa attcttcatt gataaataca taatcaaggt
    53341 ttgccataca ttcaagtgca agcattacta ttctgtatcc ctctattatg aactttgact
    53401 ctttattcct attctttgat tttaatagtg ctcttgtata ctttaacttt tcattatcct
    53461 tactgtttat atttgtaatc attttatcta aatgctaata acttataaat ttttatatta
    53521 gcacagcctc cttactttta atttaatttc tctttatcta atcttacaaa taaatactac
    53581 cttcgattaa aaaaatagta tcatataact attcataatt atatgatact atctactttc
    53641 attgcaatta aatatatatt aaatagtaaa ttatcttctt ctaattatcc ccttatttcc
    53701 agatgttatc gctgttatac tagtattttg accgattata actaggatac ttccggctgt
    53761 aagttcctca tctggagaag gtgtaacatt tatattttta cctgttttta tagcaagtac
    53821 agttatctca tatctagctc ttaattcaag ctctataagt gtcttgccaa cccaactatt
    53881 tggagttacg atttcaacaa ttgaatactc tgggtcaagt tcaatatggt ctaatatatt
    53941 atctgaaact aaattgtgtg caactcttac tcccatatct ctttctggaa atacaactct
    54001 atctgcgcca attttataaa gcactttagc ttgtaattca tcctttgcct tacatattat
    54061 caactctaca cccatttctt tggctataag agtcgccatt atagatgccc ttatatcaga
    54121 acctattgca actactgcta catcaaagtt acctaaacct aatgacctta acgcttgctc
    54181 atcagtaaca tccactataa gtgaatgggt taccttgtca gatatacttt gaactgaatc
    54241 ttcatttttg tctattgcca ttacttgatg tcctaaaaga tgcatagtag acgcaactga
    54301 acttccaaat ctcccacacc caatgactat atattgcttc atctcgaaac ttcctcccta
    54361 atacacaatt tatataatat ctcttaaatt aattgtttac acatacaaaa cttatacaca
    54421 atatataatt ttatatacac agattaattt aattttgatt taccttttta tttgtatttt
    54481 atttccctgt ttttttattt cattaattaa ttttgttcgt tagtcgattt tatttcttca
    54541 tataattaca tctaggctca tttattttat caacagattt acagtgctac tctaaatcca
    54601 ttataaattt atattactcc ttggtaactt aaccaaccat aattttacct tctgcatatc
    54661 tgattggttg actctttctt ctaccaccag aaagtatagc cataaataaa gtaagagaac
    54721 caactctacc cataaacata aagattatta ttataatctt acctaaagca tttaagtttg
    54781 gagttccagc taaacttgaa ccaactgtag caagtgctga tgtaacctca aaagctgatt
    54841 gaactaatgt aaaattaggc tgagttattg aaataatcaa tgttccaaaa ataactgctg
    54901 atatactgat tacaaatata ccaagagatt tttttatagt tgatggagct aatcttcttt
    54961 caaaagcttc tatatctgat tttcctgata gaaaacttct aactgtaatg attaaaacag
    55021 ctagtgttgt tgtttttata cccccaccag ttgatgcagg tgatgctcca ataaacatca
    55081 aaattatcat tacaaataca ctactttctc gtaaagtagc taaatcaagc gtattaaaac
    55141 cagcagttct tgctgttact gattgaaata ttgctgatag tacttttccc tttaaaggca
    55201 agtccgccat agtagctttt tgattaaatt ctataagaaa aataaataat gcacccacaa
    55261 aaataagtgt agcagttgaa aacaatacaa ccttagaatg cacatttaat tttgaaaatc
    55321 ttctttttct tacaatatca agtacaacag ggaatcctag ccctccaagc actataagtg
    55381 cgcaaacagt cattgatact gtaaagttgt ttacataaga atttaacgat gtaaatgggc
    55441 cacttacact gcccatcaag tcaaatccgg cattacaaaa cgctgatatt gcgtgaaata
    55501 cactatacca tatcccttta gacaaaccaa attgtggaat aaagacagtt gataaaacca
    55561 gtgcacctat tccctctatt gttatggtta ttattaatac aaatcttgta agtcttacaa
    55621 gtcccgataa atcagcttga tttaatgact cttgtattaa taatctttct cttagttgta
    55681 ttttttttcg tgccataagt gaaaacattg tggctacggt cataaatcca agaccaccaa
    55741 tttgtatcaa tgttattata actatctgtc caaataaact ccaataagtt gctgtatcta
    55801 ccataactag accagtaaca caaaccgctg aagtagccgt aaatagagca tttaataagc
    55861 ctatactctc tccactctgc gacgctatcg ggagtgttaa caacaatgct ccgattacaa
    55921 taatcgcagc aaacccagat accattattt gagtaggacg cattccatct gcgtagagaa
    55981 taagtcttct aactattgtt ttcaactttc tttatacctc cttaacataa aatcactact
    56041 gttaagaccc ttaatttgtt tatttttaga gctttcctct aaattattat tctattatag
    56101 tataaatatt gtataaagac aatgatagta atttttataa tttctgtttg gaatatttta
    56161 aatttttata tatatctttt aatttaaatt gcaccaaaaa catctatatt ttttacatat
    56221 aataggtcta aaactatcat agcttttact attttgtact taaaatttat ttatcatttt
    56281 accagtataa atttcatata cttttttgaa gttaaatttt ttatattatt tataatctta
    56341 tctatatctt tatgttaaat tttcttaaca tgcatttttt atatttaata tagtaaaata
    56401 attaataact atatccatga ttggaggatt tttatggtta aatccaagaa gaaaatattt
    56461 gtttttctaa ttttaattgc agtttttatt atatttgcat catacataag aaattatact
    56521 aatgatacaa aaaaagattc tgttagagga actattcctt ttgaaaaaat ggaatataag
    56581 cgtcctaata tacagtcaat ttgcgaaaac attaacaagt gtaacgacaa acttttaaca
    56641 gctaaaacag ctaaggaaca attaaattta tttaatgaag ttgataaaat ttatcaggat
    56701 ttttacagta cacttactat agcaaaaatt agaaataaca tagattcatc agacgaattt
    56761 tactctaagg aatataagta tcttatgagt aaatcagtag atgttgacat gtcatacaaa
    56821 gactttcaag atagatttgt aacttctaaa ttctctaaag aattagaaaa agaacttgga
    56881 aaggatacat ttaattatct aaagaacatt ggaaaactta attctaaaga agttgaaggt
    56941 ttgcttaaaa aagagcaaga cctagttgta aaatatgaag atttattagc taaatctaca
    57001 gtatcaatag atggtataga ggtagacttt gaagaagcct tgtcaagacc aaatcttagc
    57061 cctgaagaat atgtgaaaat ttattcagat tacttaaaaa aatacaatcc tatatttggt
    57121 aacatattct tagaacttat acagacaaga actgaaatag caagtaagca aggatttaag
    57181 aattatatag attatgccta tatgaaccta aacaaagact attctcaaga agaagctaaa
    57241 aaatttagac aagatgtaaa agattacata gttccattat atagagagat ttcatctaaa
    57301 ccatctgatt cttctattta tattaaagta tataaaaatc gctcatttag gaagtttgat
    57361 aaagtacttg aagatatatc tccaaaacta aaagagagct tcgactatat gaaaaaatat
    57421 gacttgtacg attattcttc tggaaaaaac aaatcacctg gaggatatac tacttatata
    57481 aataaatata aagcaccttt cttgtttaat acatgggaca attctttttt aggtgttact
    57541 agttttgctc atgagtttgg tcatttttat aattactaca acagtattaa cttaaataat
    57601 aagatgcaac caagtataga tgtatgtgaa gttcattcaa catctttaga aattctattt
    57661 tataaatatt ttgatgattt ttttggtaaa caatctgaag ctataaaaaa agaacactta
    57721 tcgattgttt taaatactat tattgatgct tgtctttatg atgaatttca agaaattata
    57781 tacaagaatc catatatgag tctaaatgat atcaataaat tgttttttga tttagaggaa
    57841 gaatatggag tttccaataa tatacttaga gaaaaaaatg ctcctttttg gatacttgta
    57901 tctcataact tccaagttcc tttttattac ttgagttatg gtcttgcatc tgatgtatca
    57961 cttcagatat ggcaattatc acaagaagat tacagaaaag ctgttgatgt atatatggat
    58021 tttttaaatc aaaatactga tgctggattt aaagatgtgg tagaaaaggt aaatttacaa
    58081 ttacctttcc aaaatggaaa tttagaggaa ataagctcta ctttatatga ttattttggt
    58141 atagataatc cacttgaact aaaaaatgct tcttaatttc taatacttta tactcactct
    58201 taagatttag tattagattg aaataagtga tattttttca cacacaatta atgtttaata
    58261 aaattatatg gtaaagtatc agaaattttt aagactcttg tctttataat ttctgatact
    58321 ttatttatta ataatattat tattttttta tatatataat taaaaggatt gtggaaatca
    58381 ataaaaatat ccctgtaaaa atagcactat tcatatggaa cttaatagaa cttgcatctg
    58441 ttaccttatt attcttaatc cagaacccac aaaccatagt tgaaagaaaa agtaaaacag
    58501 tgataagact tgaaccaata gttataattt tcatcttaca tcaacatcct ctccaataat
    58561 attttctatt aaaatatcaa tgaatttatc tcgctcatat ttattcttta tatttatacc
    58621 actgtataac tgaaatgatt ctgtagataa agcagaaatc tgtattggta aaataatttg
    58681 cagggcaatg attcttagac tcatttcatc ttttttattt ccaaaaattt tacgaagcat
    58741 agggacaata tcaagttctg cttgcatatc tccattggtt atacattgat tcaatacaaa
    58801 aggaagcact ttttcataat gtaatccagt atcacacaat ttttttaata aattttttaa
    58861 atcttcaata ggtcttagag tatatacact atcgtcatat agctctgcta ttatatttga
    58921 catcacatct cctatggcag tactcaacaa attatccttt gttttaaaat gataatttat
    58981 taaaccaact ccaacatttg cacgctcagc aatttttcta actgtaatct cctcaatatc
    59041 atctacttca tttaaaagat tcaatgtaac ttcaattata cgttctctag catctttatc
    59101 attacttttc ataatagacc tccaaaacaa ttaacatttt cggttctgaa catgtttagt
    59161 ataatatttt tttcatcata tgtcaatata atttaattat aattttagtt gactctaaca
    59221 ttatgatatg gtttatatta atattaagct aaaagtacct ttataaagga gacaaaaaca
    59281 tgtttaagat aggcgatttt tcaaagctaa gtaaaattag tattcgtatg ttacgtcatt
    59341 atgatgaaat aggactttta actccttctc atacgaataa aactaatgga tatagatact
    59401 atagtgcaga ccaactttct actacaaaca gaatccatgc actaaaagat atgggctttg
    59461 gcttgtattc tataaaagaa attttgacag aatataacga taaagaaagt ctcataaaat
    59521 atctaaatat ccaccattct caagtaaaag aacaattaga agatacacag aaaaaactat
    59581 taaaaataga aaccactatt aaaagaattg gaggaaatga tattatgaaa aattatgatg
    59641 taactataaa gaattttgca ccaaaatata tgatgacact tagaagggtt ataccaactt
    59701 accaagacga aggaatgtta tggcatcaag tatttttaga gacaaaagac cagaatgttc
    59761 aaattgaacc cccaaagtat tctaaagcag ttttttatga tactggatat aaagaagatt
    59821 atgtagatgt tgaagtacaa gttgctgtat ctggaaagta taaagatact gaacatgtta
    59881 aatttaagac tgttccaagt gtgactgctg caactgcaat tgttaatgga aatttcaatc
    59941 aagttgcaga cgcttgtgag gctattggta attggatatc agataataac tatgatgtgg
    60001 atggtcctat gtttaatatt tatcatgtaa gccctggcaa cgatagtaat cctgataatt
    60061 gggtaacaga ggtatgcttc ccagttaaaa agaagtaatt tttatattaa ttggataata
    60121 ttttaatttg ttagacaaat tacttttagt gttatgtata aatacctaca atttgattag
    60181 gatattatct taatttgtta aacaaattac ttttagtgtt atgtataaat atctacaatt
    60241 taattaggat attatcttaa tttgtcagat aaatcaatta taagattata tactatcctt
    60301 atactctagt taaatatatt ttaatcacta atataaatta gtttttttaa caaaacaata
    60361 aaagagtaaa gtacaaataa ttcctttgtg ctctactctt tttaactttc tttagacaat
    60421 aatacaatga taaatataaa aaattatata ttccattcta tagaaatatg ctcaccaata
    60481 acatgtatgt tgttaatcaa tatattatat caaattatat caaaattaca taaaccttat
    60541 aggacaatca tatcttatta caagaaaaat gtcttatcca tattgaataa gtcattcagt
    60601 tcatatacaa agtcaatttc attgagaaac atttaatata tgtttataaa aatttcatac
    60661 tattctttca tatttacatg tgatataatt tattaactca taattttgtt aatcagttgt
    60721 gattgtagat tatttatata atctaatatt ttaagaaggt ggtgtaataa ctttgaaatt
    60781 aaaaattgtt ggtagtggcg gtatgtcaat tattccaagt tcattttgca aatgcaaaat
    60841 atgtgaagaa gccagacaaa aaggcggaag atatgaacga ttagggccaa gtttatatat
    60901 tgatgatata aaaatgctga tagacacacc tgaagatatt gcagtagctt gtaacagaca
    60961 aaaaatatcg gaagtaaaac atatttcaat ttctcaccat gacccagacc atgttaaggg
    61021 tattagaatt gtcgaaaaaa taggatgtga ctttatcaca ggagaaaata atccaattgg
    61081 cttttatgcg cttcctgaag taattgaaga tataaaccga acgaatctcg attgtcttaa
    61141 atattatggt aatgttataa attgcatttc tattaatgaa acttcgcatg taaagataaa
    61201 taattttgat attgatttga ttaacaataa cccagacagg aatataacct tctatgttat
    61261 caaagagaat gaaaaaaaag tcatatatgc ctgctgtaat cccaagccat ttactcatag
    61321 tgatatgtac tttgatgctg atgttttaat aataagtcta gtttctgatg atggtatatt
    61381 aaatgatggt acaaaactta aagacacacc atttaaagat gaaatattta ctttagatga
    61441 gattgttgaa attaaaaact attatagaat taaaaagatt atcattacac atattgacga
    61501 aatatgggga aaatcatatg gttattacag tgaattagaa aagaaacttg ataacattta
    61561 ttttgcatat gatggtatgg aaattatagt ctaaatcatt aagtaataag cataatgcaa
    61621 aataagaaaa cttcaattta acagtatagt taaactatgt aatatcaaca tatctcagtt
    61681 tttacaaaat atcatagtat ttatctttat aaaatttcaa gtcctacata ttttaatact
    61741 tcaatatcta aataaagtaa aatcaaaaat atattttata tacattatag acggcttatc
    61801 ggcactagat aagccgtttt gtcacaatta ttatttgctc aacaaaactt ctcataatat
    61861 ataacagatt gaatctccaa ctgatactta attaccgaaa ctcttattcc ttaatatgtt
    61921 gttgcattaa ccaaaccttc atcatcattt tttgtggcaa tagttttgct aataaatgac
    61981 tggattttgt atttatacca tacacagaaa tatccttatt tttctttgca tccttcaatg
    62041 cttttttggc aacaatgtct ggagacacta tgcctgggaa attttttgtc cctttttcag
    62101 ctacaactat acctctctta aatagatttg tactcatcca acctggacat acagcaattg
    62161 catttatccc tttactctta agttcaacat ttaatgctct tgtataattt cttataaacg
    62221 ctttagttga actataaata ttttgatatg gcaatggctg gaatgatgct tgtgaagaaa
    62281 tattcatgat atggcttccc ttttgcatat atggaataca tataagtccc aatgctacaa
    62341 cagcactaat atttaaatca atcatattaa tagattcatc tatacttaaa tcattgtatg
    62401 aacagaattt tgcaaaacca gcattgttta taaggtattt tatacataca ttttctttac
    62461 ttaaaaatgt accaatttct tttacttctt ctatttttga taaatctttt gaaaaaattt
    62521 ttaccttact tccaaattca tctactaatt gatttaatct cgccttgttt cttgcaactg
    62581 cccatatttc tgttatttct tcttcattta ttaataactt tagaaactct ttaccaaaac
    62641 cactattagc acccgttata attgcaatct tcttataact cataattatt ctcctttacc
    62701 ataagtttat acgctcaaac tgtaaactta ttttttacaa ataaaacacc ctctattcag
    62761 atgttatatt catattattt gagatattat atttatatca ttttcaataa ttgttatata
    62821 gcataaaaaa tagtgttaat attatagaat cggtattgat tatatt
//
LOCUS       DAEPHU010000015        61314 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 01A10CD0081
            SAMN05941466-rid12468953.denovo.015, whole genome shotgun sequence.
ACCESSION   DAEPHU010000015 DAEPHU010000000
VERSION     DAEPHU010000015.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941466
            Sequence Read Archive: SRR6291087
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 61314)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 61314)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068158.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 22:43:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,892
            CDSs (total)                      :: 3,805
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 87
            rRNAs                             :: 8, 1, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 55
            CDSs (without protein)            :: 55
            Pseudo Genes (ambiguous residues) :: 0 of 55
            Pseudo Genes (frameshifted)       :: 21 of 55
            Pseudo Genes (incomplete)         :: 28 of 55
            Pseudo Genes (internal stop)      :: 16 of 55
            Pseudo Genes (multiple problems)  :: 8 of 55
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..61314
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941466-rid12468953.denovo.015"
                     /strain="01A10CD0081"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            complement(1..2115)
                     /locus_tag="KR231_001015"
     CDS             complement(1..2115)
                     /locus_tag="KR231_001015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding domain-containing protein"
                     /protein_id="HBH0003420.1"
                     /translation="MSENKQVVNCDIIASNSKHNMCEYDAELLTFFPDEIAHLIEINN
                     KLDNAFKKAENLVDKLDKDYMDAKMYMVKNRGEIDPHEMFQNEQGLKQIDNYGAFMVK
                     VRDKINKIKDSPYFARIDFRLKDMDDESKYYIGRFAFDYEDELIILDWRSPIASMFYD
                     YEIGKAGYDAPIGWVDGEITRKRQFKIKNGKLEYALESSINIQDDILQKELSHTSDEK
                     MKSIISTIQKEQNQIIRNDKADTLIIQGVAGSGKTSIALHRIAFLLYRFKDKISANNV
                     IILSPNKVFGDYISNVLPELGEEPLCELSFENIAEVQLDRVINFESEKDPLEINDAKW
                     SERVRFKSTLDFVKLIDDYIKQMPNKIFIPKDYTFGSFTAKSDWIQSRFEAYNRYPVK
                     KRLEKVAEDIHYKFESDNIMEEDLPKVKSILKSLNGMLTIKNTLTLYKDFFKQMNISN
                     MFVMAEKKTLEWSDVYPFIYIHAAYEGIQEDKIIRHIVIDEMQDYTPIQYAVINLLFK
                     CKKTILGDFGQLVNPNHTHTLDDMKQLYNDGELVMLNKSYRSTFEIINFAKKIQDISS
                     LEPIERHGEEPALLKCNNEQDEINKIKIEIEEFKKSDNATLGIILKTDNDAKAVYDAL
                     REEYSVHLISSESSSFTKGVSITSIKMSKGLEFDEVIVPSVNNKTYYSDYDRSLLYIA
                     CTRAMHKLKLTYTCELTQLIDM"
     gene            complement(2199..3035)
                     /locus_tag="KR231_001016"
     CDS             complement(2199..3035)
                     /locus_tag="KR231_001016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBH0003421.1"
                     /translation="MSYKVINVITAIDYIEEHLSEKLDLDIVANAVHYSKYHLHRTFT
                     TSVGLTMHDYIKRRKLTEAAKLLVFSKKPIIEIALIAGYESQQAFTSIFKAMYKKSPN
                     KYRKEQEFYPLQLRFVLKKDNLFSKNVLELEKEIKLASMSDIPLWMNLVRLVIDGFPN
                     LQEEEYIYQLEQYILEERALILKLNNVAIANMVFNRETRSIDFFGIHPQYRNSDIAQV
                     FLKKVIEDFLIDTDISITTFREGDKADTGHRDMIKKLGFAEAELLVEFGYPTQKFILP
                     LS"
     gene            complement(3619..3981)
                     /locus_tag="KR231_001017"
     CDS             complement(3619..3981)
                     /locus_tag="KR231_001017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HBH0003422.1"
                     /translation="MKIYDILTRFYIQDIEKAIPFYENLLKEKCSLRFSYKEVGLELA
                     QIGNVLLLSGSDDALKPFIETKSTFMVDSVDEWRSYLLDNGAVVVRDKKKVPTGYNMT
                     LRHPDGTIIEYVQHTKQD"
     gene            complement(4215..4679)
                     /locus_tag="KR231_001018"
     CDS             complement(4215..4679)
                     /locus_tag="KR231_001018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GyrI-like domain-containing protein"
                     /protein_id="HBH0003423.1"
                     /translation="MTRISNITIAEQSEYCFLAIRKTIDFMVEFSEFSKQSFEKISKY
                     LEERGILSSGAPIVCFHNMDLVKLDVEVGFPVATYIDGKNEILQKIVPAQKIITAIDL
                     GLYELQDPTLEDLFSWANSNGYKLHGDIYYQYLNDINRPASEYLTKMMLPII"
     gene            complement(5108..6529)
                     /gene="nhaC"
                     /locus_tag="KR231_001019"
     CDS             complement(5108..6529)
                     /gene="nhaC"
                     /locus_tag="KR231_001019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Na+/H+ antiporter NhaC"
                     /protein_id="HBH0003424.1"
                     /translation="MKERECRKASLFDAMIPITCLILFLSLGVLVYGSSPHVPLIGAA
                     AVAGLVAVYRLGFKWKELELSMFNSIKMAMQAILIIIIIGVLIGTWIVSGVVPCMIYW
                     GLKILSPNIFLVASTLVCAIVSLATGSSWSTMGTVGVALLGIGQSLGMPIGLIVGSII
                     SGAYFGDKLSPLSETTNLAPAMAGTDLFTHIKYMLYSTIPSLLICLVIYGVIGMKYSG
                     QALDIKQIELIRSTLDSTFNTLSPVLLLAPAIVIGLVVFKVPAIPGLIVGAVLGVLFA
                     VVFQGESMNTILDAAQNGYVSSTQIQEVDALLSKGGIMNMMSTVSLTICALSLGGILE
                     KTGMLEVVASSLLRLAKGVFGTVLCTMVTCTITNIIAGEQYLSIVIPGRMYNKEYKKR
                     GIHPKMLSRALEDSGTLTSPLVPWNTCGAYITATLGVSALTYGPYALLNIINPIVSLV
                     LIACKFKIARIEDEPETCLNFDV"
     gene            complement(6559..7623)
                     /locus_tag="KR231_001020"
     CDS             complement(6559..7623)
                     /locus_tag="KR231_001020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine/ornithine racemase family PLP-dependent
                     enzyme"
                     /protein_id="HBH0003425.1"
                     /translation="MYPRLEIDIEKLKHNAKLISQMCHERNIKISFVTKSFCAQKEIV
                     EEICSEGIDHIADSRIQNLKNLQDINLPKILIRIPMLSELEEVINYCDISFNSELGTI
                     KKLNELCESKNIIHKIVLMFDLGDLREGYFYEEDFFNNVREIVRLKNIEIIGIATNLT
                     CYGAIIPSRENIGRLVSIAKRMEEKFGINLEIVSGGNSSSIHLLINNNMPEGITNLRI
                     GESILLGRETAYGENINGTYQDAFKLICQVVECKEKPSVPIGEIGVDAFRNKPVYEDK
                     GILKRAIIAIGKQDINIDSLIPIDTDIKILGASSDHMILDVSNTKYDYKLGDNLEFLL
                     TYGGIMSSSTSKYVSKKIIV"
     gene            complement(7608..9017)
                     /locus_tag="KR231_001021"
     CDS             complement(7608..9017)
                     /locus_tag="KR231_001021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate mutase L"
                     /protein_id="HBH0003426.1"
                     /translation="MENSKVSLKIDVLVAEIGSTTTVVNAFHDINTNNPIFLGQGQAP
                     TTVFEGGDVRNGLSGAIKDLANKLSVDDIEYNDMFATSSAAGGLKMTVHGLVYDMTVK
                     AAKEAALGAGAVIRQITSGRIKRTDLNKIKEINPNIILIAGGVDYGERDTAIYNAEMI
                     ASMNLGIPVIYAGNVENQEEIRLIFEDTNYKLYITENVYPKIDLLNIEPTRRIIQSVF
                     EEHITTAPGMKYIKEMVNENITPTPGAVMEASKLLYKNIGDLLTLDVGGATTDVHSVT
                     DGSDYINKILVNPEPTAKRSVEGDLGVYVNMKNIVEVIGKENLQSELSIDIDAVIENY
                     PPIPKSKEEILFVERLTKEAVVKAMLRHSGKIRNIYGTTGKVKIAEGKDLTEVRYIVG
                     TGGALTRLPSRIEILDNMLKYNKNNELLFPKEKTKILIDNDYIMASMGVLSKKYEEAS
                     LKLLLKSLNFEEERLCILG"
     gene            complement(9017..11221)
                     /locus_tag="KR231_001022"
     CDS             complement(9017..11221)
                     /locus_tag="KR231_001022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892628.1"
                     /note="Presence of a B(12) (cobalamin)-binding domain
                     implies dependence on cobalamin itself, in one of its
                     several forms, or in some unusual lineages, dependence on
                     a cobalamin-like analog; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalamin-dependent protein"
                     /protein_id="HBH0003427.1"
                     /translation="MLKENKKLDIDYILKDLDKYKPKRRGWVWREHLENLEMGPFKYK
                     DCTKPLKKSVGLPSSKYFNNIDPQPSPVITTEIASGRFEDDIRRMRMAAHHGADHLMV
                     IRTAGQSHFDGLIEGTPQGIGGVPITRKQVRAQRKALDFIEEEVGRPINYHSYVSGVA
                     GPEVAVMFAEEGVNGAHQDPQYNVLYRNINMVRSFVDACEAKKIMAFANIAQIDGAHN
                     ANATAREAWKVMPELMVQHALNSIFSEKIGIDKSNICLSTVPPTAPPAPCLKIDLPYA
                     VALRELFSDYKMRAQMNTKYMESSTREATVTHVLNLLTSVLTRADIQSTITPDEGRNV
                     PWHIYNIEACDTAKQALVGMDGLMDMIELKDVGELRDKARELKERAVLYMEEISEVGG
                     YFESVEQGFFVDSGNYPERNGDGISRKIKGGVGEGTVYEREEDYLAPVTAHFGYNNVA
                     QYDENAIDNPSMLIDGCTFENPDKIIYIDELDDFDNVENRLKESYEYRNGTKIKPEME
                     WCADGIIMITMMLPTDKRTAEFAALEFVKKMNLQEIEVISREVMHESEGTRIEVKGRV
                     PFDIDLNNLVIPEEPKVLTDEEIRADIEEKPMKIVSATVGEDEHSVGLREIIDIKHGG
                     IEKYGIECHYLGTSVPVEKLVDAAIELNADAILASTIISHDDIHYKNMKKLHDYCVEK
                     GIRDKVMIACGGTQVTPEIAVEQGIDAGFGRNSKGIHVATFLVEKRREMSNK"
     gene            complement(11215..11589)
                     /locus_tag="KR231_001023"
     CDS             complement(11215..11589)
                     /locus_tag="KR231_001023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine aminomutase subunit alpha"
                     /protein_id="HBH0003428.1"
                     /translation="MKKREDDFEVRRKHLQELSDDELKERFWSLATQIVEPMIELGKK
                     NTTPSIERSVLLRMGFSSLEVKPILEGVMERGLIGKGAGHVVYKLAKSKNITVREAGL
                     LLVKGEYWDEVTCLFREGVESC"
     gene            complement(11667..13097)
                     /locus_tag="KR231_001024"
     CDS             complement(11667..13097)
                     /locus_tag="KR231_001024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent lyase/thiolase"
                     /protein_id="HBH0003429.1"
                     /translation="MNNSTSMKDMSYQAVMGRNNEIMKNAIGLDYSSFEQEGIGFDYE
                     KMMSETGYTLQDIEAIQSQYAVGNTPLIELKNLTKLARKCAKEGKGARIFVKDEAMNA
                     SGSFKARRAATAVYHAKQMGYKGVIAATSGNYGAAVASQAAMQGLKCIIVQECYDSNG
                     VGQPEIIEKARKCEAYGAEVVQLTVGPELFYTFLVLLEETGYFNASLYSPFGIAGVET
                     LGYELAIQFREKYKKDPDIVVCTNAGGGNLTGTARGLIKAGSINTKVVGASVDLKGLH
                     MASDNQFNKKSFTTGHTGFGIPYCTWPDRSDVPRSAARPLRYMDRYVLVKQGEVFYTT
                     ELLAQLEGIERGPAGNTSLAAAFSLAQELDEDKAIVVQETEYTGAGKHICPQLTFARE
                     NGIDIKFGNPREEIAGVNLILPERPELLKCVDIDMNKIRKSFIKNCISNNHIDNIDKL
                     SNRDIEFLMEEVKSSRDFVVDVLNNL"
     gene            complement(13090..13398)
                     /locus_tag="KR231_001025"
     CDS             complement(13090..13398)
                     /locus_tag="KR231_001025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-amino-4-ketopentanoate thiolase"
                     /protein_id="HBH0003430.1"
                     /translation="MDAKINDWVIIHNIVLTPEERAPQVPEDTKKVSLEMWVKGFIQS
                     DASIGDLVEVKTITGRLVKGNLLKINPYYTHDYGKCIPELLQIGIQAKEILFGGVYNE
                     "
     gene            complement(13519..14586)
                     /locus_tag="KR231_001026"
     CDS             complement(13519..14586)
                     /locus_tag="KR231_001026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-binding protein"
                     /protein_id="HBH0003431.1"
                     /translation="MRKVRVGIWGFGAMGIGMANMILKKEGIEIVSVCSRSTSGKSMY
                     DVLGIERGERPEVIINKNYEEVFREKSVDVVLLATDSFTKKAFDKINFLLNRKINVIS
                     TAEQMAYPQADDADLAKKMDEVAKENGVSILGTGINPGFVLDLLVLALSGTCEEVTSI
                     KAKRVNDLSPFGKSVMVEQGVGVTREEFIKGVEDKTIAGHVGFVESINMIADGLGWKL
                     DKIEQTKEPIMTTVDRKSKYGEALAGNVAGCRQCGYGYVNGEVLIEMEHPQQIIPEAE
                     GIKTGDYVSIKGIPNIDLQINPEIPGGVGTYAMIVNSIPLIINARPGLKTMLDIPVPR
                     AIMGDIRNQIEVELEEESKAN"
     gene            complement(14842..16215)
                     /locus_tag="KR231_001027"
     CDS             complement(14842..16215)
                     /locus_tag="KR231_001027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HBH0003432.1"
                     /translation="MNEILENIDEGVHFVNKDGKTIIYNNSVQKMEKMNRHDILTNSF
                     FDIVNKMKINRSTLLEVLEKREVIKDNIQKYLDKNGKEITAINTTIPIDIKGEFVGAL
                     EISKNMTTIENLLNRNYKKNLVNKVSIRQKKGYEFDDILGESNLIKEAIAKSKKACKS
                     DASVFIYGETGTGKELFSQSIHYGSNRRNYPFIAQNCAALPESLFEGILFGTSKGGFT
                     GAIDRPGLFEQANKGTLLLDEINSMPIMLQAKLLRVLQEGYVRRVGGTKDIPIDVRII
                     ATTNESPKVILNEHKMRKDLYYRLNIIHIKIPPLRDRKEDIPLLCKKFISKYNKKLNK
                     KVVGISDEAIKILKNYDWQGNIRELENIIYCTMSMMEDEVQIETSMINLNDYYTLKEN
                     KESNNYSLNDLEDKTLSKIISEIEEKYIYESLEKASYNITKAASILGMNRQNLQYKIK
                     KYNIKIL"
     gene            complement(17190..17330)
                     /locus_tag="KR231_001028"
     CDS             complement(17190..17330)
                     /locus_tag="KR231_001028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426234.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0003433.1"
                     /translation="MENLMMSIITGVIASYIYDKLKSHSERPTKSGWELNIKFQKSKS
                     SK"
     gene            complement(17588..18748)
                     /locus_tag="KR231_001029"
     CDS             complement(17588..18748)
                     /locus_tag="KR231_001029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp27"
                     /protein_id="HBH0003434.1"
                     /translation="MKLNKTLLAIGMSVSLLIASCPTSNALSSINSIKGTNKYETAGL
                     IADKQNYDIAILINSENGLSDGLSASGLSGAKNAPILLTKKDTIPSETLKRLEKVKEV
                     YLIGGKNSIGASVQKILSDKKISINRISGTDRIDTSHKVAKEIGSVSAVKKVILTNAF
                     KGEPDAMSVASIAVRDKSPIVLTDGNTTSFATDGLETYAIGGKVSISDKLINETKATR
                     IGGVDRYDTNKQIINKFYNGSKEFYIASGTDLVYSLVGSTIAQKTPIVLVGNGSNKSI
                     LKNASKITAIGNIDDVVIKQCLNITNNVGDSNTGIVKDTNSNNTNKPSNEPSSNNPGL
                     TDKSTVYVTPNGKSYHLTKNCSTLKRSKTINKVTLKQAKSQGKIDPCNVCVK"
     gene            complement(18919..19122)
                     /locus_tag="KR231_001030"
     CDS             complement(18919..19122)
                     /locus_tag="KR231_001030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4236 domain-containing protein"
                     /protein_id="HBH0003435.1"
                     /translation="MGFNFRKSINLGGGLKLNLGKKSVGISAGVKGARVSVNSKGRKS
                     ATLSIPGTGISYTKTSTKKRKPK"
     gene            complement(19209..20243)
                     /locus_tag="KR231_001031"
     CDS             complement(19209..20243)
                     /locus_tag="KR231_001031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YHYH domain-containing protein"
                     /protein_id="HBH0003436.1"
                     /translation="MFKKKLIAVAMSITMISVGSFSYAHSGRTDSSGGHRDNKNKSGL
                     GSYHYHCGGYPAHLHNNGGCPYTGGGSSSGTATSVNNEEKQKRSVGEKGYNQGYEDGY
                     KGNYSSSNYSGDYSDTYESKYSEGYEKGKAKLEEEEKEAKETGYNLGLTGAKSNNTYE
                     KEVLKNAYDTGYSTGYNEYKTKKIEEYKAKGIEDSNKDKEKMTFEENIDSKFIDAYNN
                     AYDEIQEQLKNDYTTQGFESAIKGERFDTSTIGNVKYANWFKEGYDNGKVKLPKAKES
                     VYNQGYNEEDFSIPDEMKSIETKLKGVYDEGLEKREEEKSRNATYGVGAGTAAVVAGV
                     VYKKKKRKKI"
     gene            complement(20765..22126)
                     /gene="rlmD"
                     /locus_tag="KR231_001032"
     CDS             complement(20765..22126)
                     /gene="rlmD"
                     /locus_tag="KR231_001032"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HBH0003437.1"
                     /translation="MSVKKKDVIEFEVDKMEFGGTSLSQVGDRVIHMKGGISGQKVRA
                     GVKKVRSKKAEVKMIELLENSPLETEETCKHFRECGGCTLLSVPYEKQLEIKEKQVMD
                     LFLKQDLFGFQFLGIEGSPENKYYRNKMEYTFGDEVKNGPLTLGLHKKGKHIDIQTVE
                     ECMLVDEDFSKILVSSVEFFNEKKLPYYRTMNHKGYLRHLVVRKGIHTNEIIVNIVTS
                     SQEDFDMYEFKDMLLGIDLKAELVGVLHTINDGLADAVQCDELRVLYGRDYIQEEILG
                     LKFKISPFSFFQTNTKGAEVLYSIARDFIGDYNDKVVFDLYSGTGSIGQVMAGAAKKV
                     YGIEIVEEAVVAANENAKLNGLTNCEFIAGDVAKVVKDLKDKPDLIIVDPPRPGIHKD
                     AIRDICGFGAKEIVYISCNPKSLVVDLVDFKGYGYEIKMVKCMDMFPNTPHCETVVKL
                     IRE"
     gene            complement(22153..22875)
                     /locus_tag="KR231_001033"
     CDS             complement(22153..22875)
                     /locus_tag="KR231_001033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HBH0003438.1"
                     /translation="MAKKQRIDKILSNLGYGSRSEIKKYCKQGSVVVNGSEVSNPGTQ
                     VDTENDEILFNGEEVIYREYIYLMMNKPDGYISATTDKYDPTVLDLIDLSYLAFEPFP
                     VGRLDKDTEGLLVLTNDGKLSHRVLSPKKHVPKTYYAKIDGVVTEEDVEAFLEGVVLD
                     DGYKTMPSQLNILKSDDESEIELTIHEGKFHQVKRMFESVGKKVVYLKRLSMGNLKLD
                     ESLELGEYRELTDEEVKLIEER"
     gene            complement(22875..23204)
                     /locus_tag="KR231_001034"
     CDS             complement(22875..23204)
                     /locus_tag="KR231_001034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1904 domain-containing protein"
                     /protein_id="HBH0003439.1"
                     /translation="MPQIKIRGINENDICKISEKMINDLVEAVKCPRDYFEIECIKSV
                     AIRDGKIADVYPFVEVAWFDRGQEVQDIVARIITDSIRNNLDVESMDLAFTVFEKEKY
                     YENGEHF"
     gene            23534..24460
                     /gene="fba"
                     /locus_tag="KR231_001035"
     CDS             23534..24460
                     /gene="fba"
                     /locus_tag="KR231_001035"
                     /EC_number="4.1.2.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class II fructose-1,6-bisphosphate aldolase"
                     /protein_id="HBH0003440.1"
                     /translation="MALITTKEMFKKAYEGGFAIGAFNISDLEQLQGVLKAAKAKNSY
                     VMIQASMSAVKYAGPHTLVEMVKAASDEIGVDVALHLDHGPNMDAIKTCIDAGFSSVM
                     IDGSHFDFEENVRITKEAVEYAHSKGVVVEAELGVLAGTEDDVTSDVHKYTQPAEAVE
                     FVERTGVDSLAIAIGTSHGAFKFKGEAKLRFDILEEIQSKLPGFPIVLHGASAVDQNA
                     VATCNEFGGNIAGAKGVPVDMLRKASSMAVCKINMDTDLRLAMTAAIRKFLAENPKEF
                     DPRKYIGAGRDAIQAVVESKIDDVLGSANSIN"
     gene            complement(24595..26226)
                     /locus_tag="KR231_001036"
     CDS             complement(24595..26226)
                     /locus_tag="KR231_001036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HBH0003441.1"
                     /translation="MDNNLIGLIEHVENPAILCKESGEIIYCNHLIDSIFSFLDIKKP
                     RNINELDSNFDKTEILTDSKKKIAFRELRMTAHIYNMKDNNNENNIVYLFEKSLISDK
                     VIEDIIEHIDEVVVVFNKDGVIEKMNTVSDEILPFKRTEVLGRNITDLVRQGLVEEPI
                     ILNMLKVKKKIYRNIVYPDGKLIAYTAVPRWDSKGKLTGGVLTGRDISRVIKLESQIK
                     YSDISEDTEYISQSKIMDNIKKVVKRAAASDSSIFINGESGVGKEIIARTIYKYSSRR
                     DKPFIAINCGAIPNELLESEFFGYEEGSFTGAKKKGKKGLFEEANGGTIFLDEIGELP
                     MQMQKKLLRVIQENTITRIGGSKPIKIDVRYISATNISHEDLRNNLKFRQDLYYRLSV
                     IPVKIPPLRERKEDIVPLVNYFLKLYNEKYNREVEVSPKVIELLEEYSWPGNIRELKN
                     IIERFVVLSAKNVIGEDEFNMLINLDMIDNETDDLSPIVVNGIMNLNDAYKIVDQIMI
                     SKAINKYGSITKAAEVIGIYPSTIHRKIKSGHIHV"
     gene            complement(26709..27746)
                     /locus_tag="KR231_001037"
     CDS             complement(26709..27746)
                     /locus_tag="KR231_001037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="electron transfer flavoprotein subunit
                     alpha/FixB family protein"
                     /protein_id="HBH0003442.1"
                     /translation="MNDIKDLSSYKNVWIFAEQREGKIAPVVIELLGEGRKLAKEVDA
                     ELCAILLGKDVDGLAKELITFGADKVYVADDALLEKYTTDAYTKVIKDAIDEIKPEIM
                     LFGATHIGRDLAPRIASRVGTGLTADCTKLEIDPEDKKIKQTRPAFGGNIMATIICPN
                     HRPQMSTVRPGVMDKAEKDETRTGEVIALDYKITQDDIRTTVLETVKTKKDLVSLTDA
                     NVIVSGGLGLGGPEGFEMLKKLADKLGGVVGSSRAAVDAGWIDHSHQVGQTGTTVKPN
                     LYIACGISGAIQHLAGMQSSDFIIAINKNPAAPILEIADYGVVGDLHEIVPMLIEKLD
                     SVDDLLEAIKA"
     gene            complement(27765..28550)
                     /locus_tag="KR231_001038"
     CDS             complement(27765..28550)
                     /locus_tag="KR231_001038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012703997.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="electron transfer flavoprotein subunit beta/FixA
                     family protein"
                     /protein_id="HBH0003443.1"
                     /translation="MKILVCVKQVPDTNEVRINKETGTLIRDGVPSILNPDDANALEE
                     ALKIKDEHDDVTITVITMGPPQADFMLRECLAMGADDAILLSDRAFGGADTWATSNTI
                     AAGISKVGDYDIIFAGRQAIDGDTAQVGPQIAEKLDIPQVTYVQDFKIEGKDIIVQRQ
                     LEDGYELIKVSTPVLLTAVKELNTPRYMSVDKIVKAYKHDVKVWTIDDLDVNKEEVGL
                     KASPTKVFRSFTPEPRGKGEILEGKADEIASKIIIGLKQKHII"
     gene            complement(28583..29716)
                     /locus_tag="KR231_001039"
     CDS             complement(28583..29716)
                     /locus_tag="KR231_001039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003483287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA dehydrogenase family protein"
                     /protein_id="HBH0003444.1"
                     /translation="MLYNKEQELLRKAVRDFVSKELDTLPAEMDKTGVMPKELIKKLA
                     DAKFISSNIPEEYGGGGAGYVSYAIVMEEIARRCASTATFVTAGSSLASLPILYNGTE
                     EQKQKYLKGIATGELIGAFGLTEPGAGSDAGGQQTTAELVGDHYILNGRKTFITNGPF
                     CDVAIVIAVTDRSKGLRGTSAFIVESKWDGFSTGAHEDKMGIRGTETSDLIFENVKVP
                     KENLLGKEGQGFKIAMGTLEVGRIGVAALALGIAQGALDEAVKYTKQRVQFGKPIAKF
                     QNTQFTIADMETKVCAARGLVYDAAQKRDAGMRVAQESAMAKYYASEIANEVAYKALQ
                     LHGGYGFIKDYEIERMYRDARIVSIYEGTSEVQKMVISSNVLK"
     gene            complement(29764..30891)
                     /gene="hadC"
                     /locus_tag="KR231_001040"
     CDS             complement(29764..30891)
                     /gene="hadC"
                     /locus_tag="KR231_001040"
                     /EC_number="4.2.1.157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="(R)-2-hydroxyisocaproyl-CoA dehydratase subunit
                     beta"
                     /protein_id="HBH0003445.1"
                     /translation="MEAILSKMKEVVENPNAAVKKYKSETGKKAIGCFPVYCPEEIIH
                     AAGMLPVGIWGGQTELDLAKQYFPAFACSIMQSCLEYGLKGAYDELSGVIIPGMCDTL
                     ICLGQNWKSAVPHIKYISLVHPQNRKLEAGVKYLISEYKGVKRELEEICGYEIEEAKI
                     HESIEVYNEHRKTMRDFVEVAYKHSNTIKPSIRSLVIKSGFFMRKEEHTELVKDLIAK
                     LNAMPEEVCSGKKVLLTGILADSKDILDILEDNNISVVADDLAQETRQFRTDVPAGDD
                     ALERLARQWSNIEGCSLAYDPKKKRGSLIVDEVKKKDIDGVIFCMMKFCDPEEYDYPL
                     VRKDIEDSGIPTLYVEIDQQTQNNEQARTRIQTFAEMMSLA"
     gene            complement(30891..32117)
                     /gene="hadB"
                     /locus_tag="KR231_001041"
     CDS             complement(30891..32117)
                     /gene="hadB"
                     /locus_tag="KR231_001041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="(R)-2-hydroxyisocaproyl-CoA dehydratase subunit
                     HadB"
                     /protein_id="HBH0003446.1"
                     /translation="MSEKKEARVVINDLLAEQYANAFKAKEEGRPVGWSTSVFPQELA
                     EVFDLNVLYPENQAAGVAAKKGSLELCEIAESKGYSIDLCAYARTNFGLLENGGCEAL
                     DMPAPDFLLCCNNICNQVIKWYENISRELDIPLIMIDTTFNNEDEVTQSRIDYIKAQF
                     EEAIKQLEIISGKKFDPKKFEEVMKISAENGRLWKYSMSLPADSSPSPMNGFDLFTYM
                     AVIVCARGKKETTEAFKLLIEELEDNMKTGKSSFRGEEKYRIMMEGIPCWPYIGYKMK
                     TLAKFGVNMTGSVYPHAWALQYEVNDLDGMAVAYSTMFNNVNLDRMTKYRVDSLVEGK
                     CDGAFYHMNRSCKLMSLIQYEMQRRAAEETGLPYAGFDGDQADPRAFTNAQFETRIQG
                     LVEVMEERKKLNRGEI"
     gene            complement(32132..32932)
                     /gene="hadI"
                     /locus_tag="KR231_001042"
     CDS             complement(32132..32932)
                     /gene="hadI"
                     /locus_tag="KR231_001042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-hydroxyisocaproyl-CoA dehydratase activator
                     HadI"
                     /protein_id="HBH0003447.1"
                     /translation="MYTMGLDIGSTASKGVILKNGEDIVASETISSGTGTTGPSRVLE
                     KLYGKTGLAREDIKKVVVTGYGRMNYSDADKQISELSCHARGVNFIIPETRTIIDIGG
                     QDAKVLKLDNNGRLLNFLMNDKCAAGTGRFLDVMAKIIEVDVSELGSISMNSQNEVSI
                     SSTCTVFAESEVISHLSENAKIEDIVAGIHTSVAKRVSSLVKRIGVQRNVVMVGGVAR
                     NSGIVRAMAREINTEIIVPDIPQLTGALGAALYAFDEAKESQKEVKNI"
     gene            complement(32971..34170)
                     /gene="hadA"
                     /locus_tag="KR231_001043"
     CDS             complement(32971..34170)
                     /gene="hadA"
                     /locus_tag="KR231_001043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isocaprenoyl-CoA:2-hydroxyisocaproate
                     CoA-transferase HadA"
                     /protein_id="HBH0003448.1"
                     /translation="MLLEGVKVVELSSFIAAPCCAKMLGDWGAEVIKIEPIEGDGIRV
                     MGGTFKSPASDDENPMFELENGNKKGVSINVKSKEGVEILHKLLSEADIFVTNVRVQA
                     LEKMGIAYDQIKDKYPGLIFSQILGYGEKGPLKDKPGFDYTAYFARGGVSQSVMEKGT
                     SPANTAAGFGDHYAGLALAAGSLAALHKKAQTGKGERVTVSLFHTAIYGMGTMITTAQ
                     YGNEMPLSRENPNSPLMTTYKCKDGRWIQLALIQYNKWLGKFCKVINREYILEDDRYN
                     NIDSMVNHVEDLVKIVGEAMLEKTLDEWSALLEEADLPFEKIQSCEDLLDDEQAWAND
                     FLFKKTYDSGNTGVLVNTPVMFRNEGIKEYTPAPKVGQHTVEVLKSLGYDEEKINNFK
                     DSKVVRY"
     gene            34847..35845
                     /locus_tag="KR231_001044"
     CDS             34847..35845
                     /locus_tag="KR231_001044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-2-hydroxyacid dehydrogenase"
                     /protein_id="HBH0003449.1"
                     /translation="MKILVFGARDYEEPVIKKWSEEHKDVQVDIYPENMTEENVVKAK
                     GYDGISIQQTNYIDNPYIYETLKDAGVKVIASRTAGVDMIHFDLVNENGLIVTNVPSY
                     SPNAIAELAVTQAMNLLRKTPLVKKKVCEGDYRWIAELLGTEVRSITVGVIGTGKIGA
                     TSAKLFKGLGANVIAFDQYPNSDLNDILTYKDSLEDLLKEADLITLHTPLLEGTKHMI
                     NKDTLAIMKDGAYIVNTGRGGLINTGDLIEALESGKIRAAALDTFETEGLFLNKKMNP
                     GELTDPEINKLLSMEQVIFTHHLGFFTSTAIENIVYSSLSSAVEVIKTGTATNRVN"
     gene            36207..36734
                     /locus_tag="KR231_001045"
     CDS             36207..36734
                     /locus_tag="KR231_001045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR04002 family protein"
                     /protein_id="HBH0003450.1"
                     /translation="MEKMNKVTSKKTTYIVTSALFASIICLTIAYILHIPVGGNNGYV
                     HIGDAFIYLAATILPTNYAIAASAIGAGLADLSTGAAIWVIPTIIIKPILVLFFTSKS
                     DKIINKRNIVASVVAGIVGLVLYMFAEGIIIGSFTSAFVMSLLGLLQPIGSFIVFIIL
                     GMALDKLDFKKRYFN"
     gene            36761..37357
                     /locus_tag="KR231_001046"
     CDS             36761..37357
                     /locus_tag="KR231_001046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR04100 family radical SAM protein"
                     /protein_id="HBH0003451.1"
                     /translation="MNILYTIENSIYVNITNTCPCSCVFCIRNEKDEVANSGSLWLEH
                     EPSVDEVKEAFNKYNLDDYDEIVFCGYGEPLMRINELIEVAKFIKEKSSIKIRINTNG
                     LSDLIHNKKTAILLKNVIDAVSISLNAPNKEAYNRVTQPKFGEKSFDYMLDFARDCKK
                     YIKEVAFSVVDEISPEEIEESKQLAKKLDIPLRVRHKN"
     gene            complement(37422..39005)
                     /gene="asnB"
                     /locus_tag="KR231_001047"
     CDS             complement(37422..39005)
                     /gene="asnB"
                     /locus_tag="KR231_001047"
                     /EC_number="6.3.5.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine synthase (glutamine-hydrolyzing)"
                     /protein_id="HBH0003452.1"
                     /translation="MINLEEKYLTRKDTYMIKILEYNGHIRNWKVLCEELGIDSSLCR
                     DERERAILVEAYKTWGYDMANHMHGMFAFALWDTVEKKLFCLRDQFGVKPFYYYETEN
                     GKLLYGSSIRKIMEQPGFVKELNEDMLQIYMSFTYVAGENTFFRGVKKLMPGHYLVYQ
                     NKTVCIGRYWKPEFHPDHSKSIEEWTDEIHTTLQKIMPEVKSENETAELFLSGGVDSS
                     YILAMSDIEKTGSCGYEEERFDESKLAQQTANILGCKNSRYIITPEEYFASVPYVMYH
                     MEQPTGDASAIVFAIECKAAAENTNICYSGEGADEFFGGYNIYHKAECYGENLKTFYI
                     GNTNIMNEGEKRKILKKYNPDVLPIEVVKGIYEETEELDTLTNMSNVDIQIWLEGDIY
                     FNIDKMSTAVGLEVRMPLTDTRIFDIASRIPSEYKVKGKENKIAFRTAASKTLPEEIA
                     FRNKLGFIVPIRIWMADDQYNKDIRDKFNSEIADKFFNIDEINEIFNDYISGNSDNWR
                     KIWMIYTFLVWYEIYFVKC"
     gene            complement(39571..40407)
                     /locus_tag="KR231_001048"
     CDS             complement(39571..40407)
                     /locus_tag="KR231_001048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HBH0003453.1"
                     /translation="MNYIIKKVLNSSVVLVHDTKDNEFILLGKGIGYGKKTGEYICGS
                     NDNQMFVPVENTKSKQFLELMDDIPVDILKITQEIIVEAEKLLNSSFNKNLYLILADH
                     FNFAIERMRKGIKITNRVFWEIKNYYPNEFKVGMVAIYMVEERLGIQLPEEEAANIAF
                     HFANAMASDGNSYDTIKYAKVIGEIINIFVFSLNRTLDKKSMHYMRFITHIKFFVERF
                     FSDSMLSSGDDLLFNQMKRSNPKEMLIALKVRDFLEKKYGKKLTNEEIAFLVVHIARV
                     KQ"
     gene            complement(40431..41897)
                     /locus_tag="KR231_001049"
     CDS             complement(40431..41897)
                     /locus_tag="KR231_001049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000110363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="family 1 glycosylhydrolase"
                     /protein_id="HBH0003454.1"
                     /translation="MRKFPEGFLWGGATAANQFEGGWNLGGKGWSVSDVAKAHFDADV
                     KDYKSNNEITTKDIEEGLAHPEDEVNYPKRHGSDFYHHYKEDIALMAEMGFKTYRMSI
                     AWSRIFPNGDDKEPNEEGLQFYDDVFDELISYGIEPLVTMSHYEPPLNIVLNYDGWYS
                     RQVINMFVRYVETICERYKNKVKYWLTFNEVDSMIRHPYTTGGLVRDRFKDKNFEEVI
                     FQAMHHQFVASALATKICHEIIPNSKVGCMLTKLTYYPYTCRPEDVLATQRKMRSIYA
                     YSDTQVFGEYPVYLLSYFKNNNIQIVKEEHDDEIMKKYPVDFISFSYYMSSCEAADTT
                     GLDITPGNTLLAVKNPYLEMSEWGWQIDSIGLRISLIELYDRYRKPLFIVENGLGAKD
                     ILTEDKKVHDQYRINYLKEHFKCMLDAIIEDGVELWGYTSWGCIDLVSESTKQMSKRY
                     GYIYVDADDYGKGTYNRYKKDSFYWYKKVIESNSIDFK"
     gene            complement(41900..43762)
                     /locus_tag="KR231_001050"
     CDS             complement(41900..43762)
                     /locus_tag="KR231_001050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HBH0003455.1"
                     /translation="MNYKKTAIDIIEQVGGSKNILALEHCSTRLRFKLIDRSKVNQDA
                     LKKVQGVMSIVNGAQFQVVIGNSVVDVYDEILKVCPLDTNDSTVKTEEKINLGTRFIE
                     FIINIFQPLIFAIAGAGILKSLLMLLAMFNILKSDSTIYTLLVAISDATFYFLPLMVA
                     VTTANVLKCNRLVAIAAVGYLLLPATTTALSEGVELFGFTIPNIAYNAQVFPAILCVS
                     FLATMEKIFNKYSPKPIRTFFVPMMSLAITVPITLTILGPLGYNVGTIFTTIILFLYN
                     KMGFLVVGLLAAFLPFMVATGMHKALIPYSINTIGKLGYEALYMTSSLAHNISESGAC
                     FAVALRTKDETLKQTALSAGISALMGITEPALYGITLQHKRAMLGVVFSSAISGTFLG
                     LFAVKGFVIVGPGLASMSMFIDPNNGNNLIFASIGFVIAILGSFIITLIIWKEDTNTV
                     ESSIGDVVEEELEEEKEVNILVTPVEGKVIDLSKVNDELFASKTLGDGVAIIPTNGNL
                     YAPCDSEVVMLFETKHAIGLRTKNGAEILIHIGINTVSMNGDGFKTFVKTGDNVKEGD
                     LLIQFDLDKISHANLDSTVMIVNNNGADYAYKVLNQSYGNVKKGSILFDVKGGI"
     gene            complement(44009..44872)
                     /locus_tag="KR231_001051"
     CDS             complement(44009..44872)
                     /locus_tag="KR231_001051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EamA family transporter"
                     /protein_id="HBH0003456.1"
                     /translation="MILSYFALLIRVVLLAFERVVVRLLGDEEGDIYKNIASSFLFFF
                     IGGVCLLPFSIMDRVSDWSFLIPCYISSLVYSIGSVAYVTSLATGEVSLVTPINSLNS
                     LFLLLLSVIFLGEGLSLAKVAGIIIMIGGVFILKKVSSFLKNVSVIFNNLPCRLMFLY
                     IFLQSVGRVLDKAFFVQVSPILYSTILYFFVGLNLFIFLAFKKKQKIICEIFSNKKGL
                     SILSGAINGYSYLALLIALNNLELSIAEPFSQVSMIITLILAHFIFKENIKEKIPGSI
                     LILIGGWLLLL"
     gene            complement(44927..45859)
                     /locus_tag="KR231_001052"
     CDS             complement(44927..45859)
                     /locus_tag="KR231_001052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728579.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-aminoacyl-tRNA deacylase"
                     /protein_id="HBH0003457.1"
                     /translation="MNNKKAVFFFCSDLKKDPVASNVIKCCEEIMDLNQTDIVIDDNF
                     VLEFKDKNNNLFHFVKTKDVISHNYKYYLPILNRHFRDYDFAGVVNWHEGENAPEHIL
                     TAHTIGDVPTGEFGNSNPRYFKNLINAIEDIKNENLLDEFTTLTEATHWSGTTYGEES
                     KLITEYSVPMLDIEIGSSSDSFNNSIAIQVLAKSLIRVFDCDEPLKTLLCVGGVHFEK
                     SFSDIIKNKEYNISIGHVLPNQWIVSGMYDDESGFEKLEKCINSIEGGIDCIVFHDKL
                     KGTYKEQCRKLGEKLNVPVFKHKILKNPKDLPIW"
     gene            complement(45945..46496)
                     /locus_tag="KR231_001053"
     CDS             complement(45945..46496)
                     /locus_tag="KR231_001053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBH0003458.1"
                     /translation="MQSLNEIIAENLKKIRKEKHLSLDKIAQLSGVSKSMLSQIEKCE
                     VNPTISTLKKITNGLKISFTSLMERQESDIELIQKSDIDHFIEDNGKYISYPIFPFDS
                     KRRFEIFMIEIEEGGNLDSNAELPGTQEFITVFSGEVTIKINGEDYIVSSGNSIRFKA
                     DVSHIYRNSGKGIAKMSMVVYYI"
     gene            complement(46725..47216)
                     /locus_tag="KR231_001054"
     CDS             complement(46725..47216)
                     /locus_tag="KR231_001054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0003459.1"
                     /translation="MIDLKIENRKGKIHVKSSEIKDILELRPDFEYVQDISNTINQEN
                     ILVFDCQLTGNSFDMDDLDIEEILEELGEEIDESYFSVLFEDVRAYLKDATDEIEADL
                     QDNYLFDNLRCYFDIYNINQEFTDFKFVFLVSFKDIKISSLANLAKIVSKRQLIGASK
                     FYS"
     gene            complement(47244..47804)
                     /locus_tag="KR231_001055"
     CDS             complement(47244..47804)
                     /locus_tag="KR231_001055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009904860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrolase"
                     /protein_id="HBH0003460.1"
                     /translation="MNKLNICIDIDGTITSPYHFLPYLNDIFNKNITEAECITHNWEE
                     LYGSGIRDVYAEFNNKYIHSYDEAKIVEGATEVISTLSKGHNLSFVTARHECLTDVTK
                     NWLSRQGFSDIDVYLLGSDYKVEKARELSCDIFIEDNPLNSVQLADDGVKVILLDTNY
                     NKDVKHQNIVRVSNWIDIEKIIKQGI"
     gene            complement(47956..49113)
                     /locus_tag="KR231_001056"
     CDS             complement(47956..49113)
                     /locus_tag="KR231_001056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAM-dependent methyltransferase"
                     /protein_id="HBH0003461.1"
                     /translation="MNKQSIGKLNMFFMGITQRNLDNRDFFIELEVIFKSGRKEFKGI
                     AIEEDNKYKFNFKGKSDLYTFNELLKNISKEAENYDGLVFKYVERGTIVVIEGDNKKV
                     NVKYLDNKEEVPKIDEFTASQIKNRDYYVKVGQANALLKEIGVLTKDGKIKNDKIRKY
                     NQIDHFVELIDSILKEIKDKDCITILDCACGKSYLSFVLNFYIKEVLKKNCYFIGIDY
                     SDVVIEASKNMAKNLGYKNMSFIKEDLTNYTPNRDVDLVISLHACDTATDMAIGLGIR
                     AKSEAIVVVPCCHKELLGQYRYEAMEPILKHGVFKARFADLITDGLRTLLLEGNGYDT
                     SVVEYISPLDTPKNLMIRAIKTKTNNDKALKEYKELKSQFGVEPTLEKLIY"
     gene            complement(49150..50091)
                     /locus_tag="KR231_001057"
     CDS             complement(49150..50091)
                     /locus_tag="KR231_001057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0003462.1"
                     /translation="MRWILVFIFLYLIPLVVIFRNYKNFKRSCIYSSIYVVLATTIMI
                     SNIYMSGLNKIKESMYYHNYISDETYDEKYVSNFKEKESTDLNQDNKKNEEISNNKNL
                     NNKQDRNIQNKESNEEGSNDIKEKNNSDSNVSVNNKSEKQEDNTKENNKYTSKEKNSE
                     DIKKIDMESIGIFKKEIYNIERAALVPMRECIPYTKDIAKNITKLSSIKKDVTNARNK
                     CKEVVKEYENMQIPELSKEKYTETLSNARDDVKKAYELREKSMESALKLINTKSPKYI
                     GKITEYLDLSDKQIESFKNRLNDLKEEINNSETNNIN"
     gene            complement(50178..50870)
                     /locus_tag="KR231_001058"
     CDS             complement(50178..50870)
                     /locus_tag="KR231_001058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HBH0003463.1"
                     /translation="MSLYAIGDLHFSTSVNKPMNIFGSNWDGHEKKIIDNWKEVVKEE
                     DMVLVLGDTSWGINLSEAKKDLDIISKLPGQKILIKGNHDYWWTTVTSLNKLYEDMRF
                     IQTNFYEYKDYAICGGRGWICPNDVKFDETDEKVYKREEHRLRLSLESARKSGHSKII
                     VITHYPPTNDKLEESLFTKLFEEYNVEKVIYGHLHGKESFKMGLKGIRNGVEYTLASC
                     DYTEFNLIKVHD"
     gene            complement(50979..51791)
                     /locus_tag="KR231_001059"
     CDS             complement(50979..51791)
                     /locus_tag="KR231_001059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP pyrophosphokinase family protein"
                     /protein_id="HBH0003464.1"
                     /translation="MEYEKWNEILAPYEHAVEELKIKFKNIRKEYLAKGEYSPIEFVT
                     GRTKKISSIISKLKRINAKDIETEIDDIAGIRIMCQFVEDIYAIVDLIKVRNDMTIIG
                     EKDYITNYKDSGYRSYHVIIKYPINSIAGSKEIICEIQIRTLAMNFWATIEHSLKYKY
                     DHYIPETLAERLRRASDAAFLLDQEMSEIREDIMKAQAMYQMKSIAIRDTLNRIQELY
                     DLGDTHKAMQYQRKLDRTETDKNITEILELKQEIDILLEQYKDTKVDDKVVQ"
     gene            complement(51842..52753)
                     /locus_tag="KR231_001060"
     CDS             complement(51842..52753)
                     /locus_tag="KR231_001060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HBH0003465.1"
                     /translation="MNLTKVKGNTFFIKGGTNTGIYVFEDNTALMIDPGLCGSRPRRV
                     NKVLDENNIQVRYIINTHGHDDHYGACNQFKEYYKDVCIMSSEYDKLYIENPELFSKY
                     IVGGKSNVFMDNILKNKMLDDIKIDKFIEAGKFELNNEMFDIIEFQGHTPGSIAVLTK
                     DNVIFVGDLLIGDEILSKYDFLFLYDIQEQINSLEKLKNIDFEYLVLGHGKQVISKED
                     SYKLIEKHLNALKKYLYQIRELLVEPKSLEILLKNIINNNNLSNNYKEYHFFKSSLVS
                     VISYLVDLEEIGYILENGELLYYTKTK"
     gene            complement(52812..53543)
                     /locus_tag="KR231_001061"
     CDS             complement(52812..53543)
                     /locus_tag="KR231_001061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YkgJ family cysteine cluster protein"
                     /protein_id="HBH0003466.1"
                     /translation="MTSIKNKDILNCIDYSIKNKLFDKLNDVYKSLPVGNCSGCGNCC
                     MESVGINLIEFLNIFCYLEDRVDLKKSCISKILDYYFEEYTRKNPCPFKDTNNRCLIY
                     EVRPLNCRMFGHWKKEDYNKNLDNVIEKNNNYRELMKKQYGFEINDEVVNYRIDYCDR
                     FIPNKDYLSKSKRLSFFDELMILDSNIYSSGNIDIDFRDRGIVEYFIESLLYRNLAYN
                     VKIRISKEYKIRKRTIDRIKRIVLV"
     gene            53632..53883
                     /locus_tag="KR231_001062"
     CDS             53632..53883
                     /locus_tag="KR231_001062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0003467.1"
                     /translation="MNRYTKIINMMGSYYTKDFEKEKKNVIKVREVKEDTVRKFFLQG
                     DCEVLVVFEDTGKEILIDDFSPEEDIKKYLGAKFINKKR"
     gene            54117..54536
                     /locus_tag="KR231_001063"
     CDS             54117..54536
                     /locus_tag="KR231_001063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0003468.1"
                     /translation="MQIYFRVKAVGKRKPMLELTPFDVSDNINCLKEAISEIVSKNVL
                     EYNEKIPEKSIINFLTNEEIESQADIGKVGFGSIYNENKQSVEKAIEVALQAFEDGIY
                     KVLINEDVIEKLDSSINLKSGDIFTFIRLTLLAGRMF"
     gene            54561..59618
                     /locus_tag="KR231_001064"
     CDS             54561..59618
                     /locus_tag="KR231_001064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4132 domain-containing protein"
                     /protein_id="HBH0003469.1"
                     /translation="MLERTRVEKNPKIIENFKNNFTKSSSKQYYDLAKSLWDCIENSS
                     YYYREPEDKFLNMIKKYYNCHYYEIKNMDELLSGPLKNALELIFTSEQVEELCQLIKR
                     KMDYTYSGGYYRKGYRSNKLVDYFRGIIRFISNYVDLIYYDFSVIDYLTLPNKVLYYD
                     SIMSDKIALEIDKGNQKVISALEEVIFGENQTALLTRQMIIGIMKSHSDKCYEMLSKL
                     LLAAKQQEGLRQQIVESLDEGTISASIYMLKTILDNNLERFSSVIRALDTWTGLGFSD
                     QKPGIIRKCLELSYKSLTDEKFRIESINSNDNLEIYFALWATATYNIYDSYSLIENLL
                     SCQEKYKKLVALYFLSHTESTYFKHSIASKNIKGDDLEILAWVITNFYVEGSVGYYYS
                     WQNRETNFDLSNTPIDKDFDARKEQFESLKHTLEILNSKTKSFSGSVFPWTWIEISSH
                     EILKCMMTLTAYDMNAQFIDVLMENCHLMSSDLRASLIVNFVNEPKTDRQREFLLECL
                     SDKSVSNRETVLSLLRKLELTDVELDKITNLLSLKTSSIRQTVIKILLEQDDSNLENI
                     ASSLIKSSNSQKCLGGLEIVNLLKDNTARQELYNKLVLLIEDIDKSKKNTSQVQILID
                     NLLGKAKNDYCKENGFGIYNPENKVQIPEQFDFKDDSNSSSKLNKIISNISLSTREDS
                     VSVATKKEAKKILDTDINKIIKVYEKFDELITENADYEYEVERWSGNVDKVLLGYSTY
                     NLTPIKYKVSNDTLDNYPLAELWRETSKKLDLDYKLILDILFYSISTCGYNETEKSWF
                     SSIYSNVLDSKKQNKIYTKLEKLKFNGLTRKLLRVLLNEFDHKEIFNYCLEIYYKLRN
                     LLTIEQCKKQRVEFTKNYYRQNEYCPALNAPILNYWLDKAHSFIYDDISFTKFFYTTF
                     SNYQLLEYKFPFYTSINVFARAHELGLMTEEQVNREMISGYNASNIIRTLTNPRWAGD
                     TLEKYPWLKDNLKTVTNRIIEIESRRGDMPTEVSHLANNIQYFEGINYFVNILVALGK
                     ETFQRGYSYGSNYSKKDVLSSLLKNCYPTKEDDSKKLKSLLKNTDITELRLIESAMYA
                     PQWVNIIEKYLNWKGLKSTIWYFHAHINEGFSAQKESEVALFSPISPRSFIDGAFDVD
                     WFLDSYKTIGEERFNILYKSAKYITSGGNSHRRAQLYADATLGKLDKDMLMKEIETNR
                     NQDKLRSFSLLPMKKGDLKEATFRYEFIQKFAKESKQFGAQRRESESKACTIALENLA
                     RSAGFGDVNRMMWALETEKLNEVAHLFKPKDIDGTSIWIDVDENGKASTKVQKGNKSL
                     KSIPKAIAKHPYVLELKSVQKDLKSQYSRAKQSLEQAMKNEIVFTVKEIANIYKNPVI
                     CPLIKNLVWVCDDNIGYVYNDKSKFFICNIEGETYKLTAKNKLKLAHPVHLFESGKWS
                     EFQHDLFSKQIVQPFKQVFREYYRINSDELSEKTISRRYAGHQIQPKKTVALLRNQLW
                     TVDYEEGLQKVFYKENIVAKMFALADWFSPADIEPPTIETVEFFDRKTYKSLELASIP
                     PILFSEVMRDIDLVVSVAHAGGVDPETSHSTVEMRIAIAKELLLLLKINNVNFEGSHA
                     LIAGNLGEYSVHMGSGIVHKKGMGALNILPIHSQSRGKIFLPFADEDPKTAEIMSKIL
                     LLAEDSKIKDPSILSNL"
     gene            complement(59804..60541)
                     /locus_tag="KR231_001065"
     CDS             complement(59804..60541)
                     /locus_tag="KR231_001065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBH0003470.1"
                     /translation="MIKVLICDDDKIVRDDIANIAKESGYVDYVKKVKDGIEAIEFIK
                     NEKIDLLIIDIDMPYKNGIDSAEEILSIDKDIHIVFVTGFADYSLESFKVHPIDFVVK
                     PFKKEKILDSINIAIDHINSHKIANNNFIEDTLFVYKIRKQIHMINFDDIVMFEKNSR
                     AINLHTKDEDIIKFYENFDDLKKRLPPNFFMTHRQYIVNLRFIHKVIPINKSSLEIRF
                     INFQENAILNKSLEKDFLYRFYRVKRF"
     gene            complement(60560..>61314)
                     /locus_tag="KR231_001066"
     CDS             complement(60560..>61314)
                     /locus_tag="KR231_001066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HBH0003471.1"
                     /translation="LGYSFLLEGVLNIILFLVLIILSFYTGFKVIRLINNNNEQEYKL
                     QKLDSKINHKDNIIIKLRSQKHDYLKHLQVVYSLLNTGLDEDAKEYIMNISNSFKSKN
                     SRYGKVSYLDAIASLKYEECLEKDISFDVYIQDFMDNLEIEPNDMSSVLLNIIDNAIE
                     SLSTIKKEKKYIRVHAYEDEFQYIIAIKNNGPKIHNVESIFWNGFSTKEGQDRGYGLH
                     LVKNILDKYDYSILVNSDDFLTEFVILIPKYY"
BASE COUNT        19792 a        10806 c         7006 g        23710 t
ORIGIN      
        1 ctacatatct ataagttgag tcaattcaca agtatatgtc aacttaagtt tatgcatagc
       61 tcgtgtacag gcaatatata acaaactgcg gtcataatca ctataatatg ttttattatt
      121 tactgaaggt acaataactt catcaaactc taaacctttt gacattttaa tagaagttat
      181 ggatactcct tttgtaaagc tagaactttc agaagatatt aagtgaacac tatattcttc
      241 tcttaacgca tcatatacag ctttagcgtc attatctgtc tttaatataa taccaagagt
      301 cgcattatca ctctttttaa attcttcaat ttctattttt atcttattta tttcatcttg
      361 ctcgttatta cattttaata aagctggttc ttcaccatgt cgttcaatag gctctaatga
      421 agatatgtct tgaatctttt tggcgaaatt aataatctca aaagtagaac ggtaactctt
      481 gttcaacata actaattccc catcattata tagctgtttc atatcatcta gtgtatgagt
      541 atgattagga ttaaccaatt gtccaaaatc tccaagaata gtctttttac acttaaaaag
      601 taagtttatt acagcatatt gaataggtgt atagtcctgc atttcatcaa taacaatatg
      661 ccttataatc ttatcttctt gtataccttc atatgcagca tgaatatata taaatgggta
      721 tacatctgac cattcaagtg ttttcttttc tgccatcaca aacatgtttg atatattcat
      781 ttgtttaaag aaatccttat atagtgtaag agtatttttt attgtcaaca ttccattcaa
      841 acttttaagt atacttttta cctttggtaa atcttcttcc ataatattat ctgattcaaa
      901 tttataatga atgtcttcag ctaccttctc taatctcttc ttaactggat atctgttata
      961 tgcctcaaat ctactctgta tccagtcact tttagctgta aaacttccaa aagtgtagtc
     1021 ttttggaata aaaatcttat ttggcatttg ttttatataa tcatcaataa gttttacaaa
     1081 atcaagtgta gatttaaaac gcactctttc agaccattta gcatcattta tttctaatgg
     1141 gtctttctca ctttcaaaat taataactct atctaattgt acctctgcta tattttcaaa
     1201 acttaattca cataatggct cttctccaag ctcaggaagg acattggaaa tatagtctcc
     1261 aaagacttta ttaggtgata ggataattac attatttgct gatattttat ctttaaatcg
     1321 ataaagaaga aaagcaattc tgtgtaatgc tatagatgtt ttcccagaac cagctacccc
     1381 ttgaataatc agtgtatcag ctttatcatt tctaataatt tgattttgtt ccttttgtat
     1441 tgttgaaatg attgacttca ttttttcatc tgaagtgtga ctaagttctt tttgaagaat
     1501 atcatcttgt atattaatgg aactttctag tgcatattct aattttccat ttttaatttt
     1561 aaattgtcgt tttcttgtta tttctccatc cacccatcct attggagcat catatccagc
     1621 ttttccgatt tcataatcat aaaacatact ggcaattgga gaacgccagt caagtattat
     1681 aagctcatct tcataatcaa atgcaaatct accaatataa tacttagatt catcatccat
     1741 atctttcaac ctaaaatcta ttctagcaaa gtatggagaa tctttgattt tattaatctt
     1801 atctcgaact tttaccataa aagccccata gttatctatt tgttttagtc cttgttcatt
     1861 ttgaaacatt tcatgtgggt ctatttcacc acgatttttt accatataca ttttagcatc
     1921 catataatcc ttatcaagct tgtcaacaag attttcagct ttcttaaaag cattgtctag
     1981 cttgttattt atctctatta gatgtgcaat ctcatctgga aaaaaagtta ataactctgc
     2041 atcatattca cacatattat gtttagaatt agatgcaata atatcgcaat ttactacttg
     2101 tttattttca gacatttaaa tcctcctttg ttaattaagt acttacactg aatcattata
     2161 cttaattgtg ttttggagtt tttaatcatt cttgctattt aacttaaagg aagaataaat
     2221 ttttgagtag gatatccaaa ttccacaagc aattctgctt ctgcaaagcc caacttcttt
     2281 atcatatctc tatgtcctgt atcagctttg tcaccctctc gaaaggtagt aattgaaata
     2341 tctgtatcta tcaagaaatc ttcaataact ttcttcaaaa acacttgtgc aatgtctgaa
     2401 ttacgatact gtggatgtat tccaaaaaaa tcaatacttc tagtttctct attaaacacc
     2461 atatttgcaa tagcgacatt attaagtttt aatattaaag ctctttcttc taaaatatac
     2521 tgttctaatt gatatatata ttcttcctct tgcaaattgg gaaatccatc tatgactaat
     2581 ctcactaaat tcatccataa tggtatgtca gacatacttg caagtttaat ttctttttcc
     2641 aactctagta cattctttga aaataggtta tcttttttca aaacaaatct tagctgcaaa
     2701 ggataaaatt cttgttcttt cctatattta tttggagatt ttttatacat agctttaaat
     2761 atagaagtga atgcctgttg actttcatat ccagctatca atgcaatttc aataattggt
     2821 ttctttgaaa ataccaataa ttttgctgct tctgtcaact ttctccgctt tatgtaatca
     2881 tgcattgtta ggccaacaga agttgtgaaa gttctatgca ggtgatattt tgagtaatga
     2941 acagcattag caactatatc taaatccagc ttttctgata aatgctcctc tatatagtca
     3001 atagcagtta tgacattaat tactttgtaa gacattgcag cttccctcct tttatccatg
     3061 caacattata tcaattatta cttagttata tttaatgaat cttgctattt tataaacaaa
     3121 tttgttgttt aagttttcaa ttcataaatt taatatatta ctttttactt tctgattaaa
     3181 gactctaatc ctttaatttt caataacttt tcatttagta aatctaaaaa gttatttatt
     3241 attttcttct tattagattc cttaattaaa tgataaatat ttatattata cgactaaaaa
     3301 cagcttttta caattattta atatgattac aaacttaccc tatcttaaag tttaatgggg
     3361 tcctgttatg aatcttttta ttttaattta agctcttcat cagtttattt tatatattga
     3421 tgtatttgat ttcatacaaa aaagagtgct tcatgaacta aaaagttcat ttttaaacac
     3481 tctcttttat gtaaataaat ttctattcta ttttgaaata ttataatttg acttataatc
     3541 tattaatacc aaaaataata aattgtacgt ctaagaatag attctaatta gttgctcagt
     3601 agtaaaatct gtttttaact aatcctgctt tgtatgttga acatattcta taattgtacc
     3661 atctggatgt ctcaatgtca tattatatcc tgtaggaact tttttcttat ctcttactac
     3721 aactgctcca ttatccaata gataacttct ccattcatca acagaatcaa ccataaaagt
     3781 agattttgtt tctataaatg gtttaagagc atcatcagaa ccagataata gtaaaacatt
     3841 tcctatttgc gctaattcca acccaacttc tttataggaa aaacgcaaag aacatttttc
     3901 ttttaaaaga ttctcataaa aaggtatggc tttttctata tcttgaatat aaaaacgtgt
     3961 taatatatca tatattttca tattttcccc ctatatatct atataatatt acctctaaat
     4021 tataccactc tacaaattat ataacaataa attaagcata gccttttgag catcttaagt
     4081 agaccttaac aatatattgg ggttacatta gaatacataa attaaatcac cttgatatta
     4141 tttaggataa aatttatgta gtagcagtaa atgttcttct aattatcaac taacaaacga
     4201 taatctttaa ctttctatat aatgggtaac atcattttcg taagatattc actagctgga
     4261 cgattgatat catttaaata ctggtaatat atatcgccat gaagtttata tccattgcta
     4321 tttgcccatg aaaataagtc ttctaaagta gggtcttgta attcataaag tcctaaatca
     4381 attgcagtta ttattttctg tgcaggaaca atcttttgta gaatctcatt tttcccatct
     4441 atataagtgg ctacaggaaa ccctacttca acatccaatt ttactaaatc catgttatga
     4501 aaacatacaa tcggtgctcc tgaagataaa attcctctct cctccagata tttagaaatt
     4561 ttttcaaaac tttgttttga aaactctgaa aattctacca taaagtcaat tgtttttcgt
     4621 attgccaaaa aacagtactc agattgttca gctattgtta tattggatat tctagtcatt
     4681 ttattcctcc attactttat tttcatttct aatcttttta taccaaatta tacgaaaatt
     4741 cactgtgtaa ctaattattt catatgaata taaaacataa cctccttcca tttcttatat
     4801 cgaaagtata gcaaaaataa tctcatcatt cttgtcacac agtgctctta taatcagaac
     4861 atacttaaaa gacttgccta atttttaggc aagtctaaaa gaaatctttt tctataaaaa
     4921 atttatacaa acaattaaaa tatcaaaata tagactaata taaaactata aatttactaa
     4981 tctgaacctc ccatggctaa agtcacaaga ttactgattt atagaatttc gcacactaaa
     5041 atatgtctta ctaattcccc acaggctacc cccctagttc ctacgttctt acataagtta
     5101 tctattatca aacatcaaaa tttaaacaag tttcaggttc atcttctatt cttgctattt
     5161 taaacttaca tgcaattaat actaaagata ctattggatt tataatattt aataaagcgt
     5221 atggaccata tgttagtgca gatacaccta atgttgctgt tatatacgcc ccgcatgtat
     5281 tccatggtac taatggagaa gttaaagttc cactatcttc taaagctctc gacaacatct
     5341 taggatgtat acctctcttt ttatattcct tattatacat tcttcctggt ataactatag
     5401 atagatattg ttcacctgct attatattgg taattgtaca agttaccata gtacataata
     5461 ctgttccaaa tacacccttt gctaatctta gtaaagaaga tgctactact tcaagcatac
     5521 ctgttttttc taaaatacct ccaagagata aagcgcatat tgttaaggat acagtggaca
     5581 tcatattcat aatcccacct ttagataata aagcatctac ctcctgtatt tgtgttgacg
     5641 aaacatatcc attttgtgct gcatctaata tcgtattcat agattctcct tgaaaaacta
     5701 ctgcaaacaa tactcccaat acagcaccta ctataagccc tggtatagca ggaactttaa
     5761 atacaaccaa tccaattact attgctggag ctaataataa tactggtgat aaagtattaa
     5821 atgtagaatc taatgtagac ctaattaatt ctatttgttt tatatctagt gcttgacctg
     5881 aatacttcat tccaattaca ccataaatta ctaaacaaat taataatgat ggtatagtcg
     5941 aatatagcat atattttata tgtgtaaaca aatctgttcc tgccattgct ggagctaagt
     6001 tagtcgtttc agataaaggt gatagtttat ctccaaagta agctccagat attatagaac
     6061 ctacgattaa tccaattggc atacctaaac tttgaccaat tcctaaaaga gctactccta
     6121 ctgtacccat tgtgctccaa gatgaacctg tcgcaagaga tactattgca cagactaatg
     6181 ttgatgctac taaaaaaata tttggtgata aaatttttag tccccagtaa atcatacatg
     6241 gaactactcc acttactatc caagttccta taagtacgcc tattataatt atgattaaga
     6301 ttgcttgcat tgccatcttt atactattaa acatacttaa ttctaactct ttccatttaa
     6361 atccaagtct atatacagcc acaagtcctg ctactgctgc tgctcctatt agtggtacat
     6421 gaggtgatga accatacact aatactccta gacttaaaaa taatatcaaa caagtaattg
     6481 gtatcattgc atcaaacaga cttgcttttc tacattctcg ctctttcata aaatagtttc
     6541 ctcctaatta tttaaacact acactataat tttttttgaa acatatttgc tcgtactaga
     6601 tgacatgata cccccataag ttaataaaaa ttctaaattg tcacctaatt tataatcata
     6661 ttttgtgtta cttacatcta gtatcatgtg gtctgaactt gcccctaata tttttatatc
     6721 agtgtctatt ggaattaaag agtcaatatt tatatcttgt ttacctatag ctatgattgc
     6781 cctttttaag attcccttat cttcataaac aggtttattt ctaaaggcat caactcctat
     6841 ttctccaata ggaactgatg gtttttcttt acattcaact acttggcata ttaatttaaa
     6901 tgcatcttga tatgttccat ttatattttc accgtatgcc gtttctctac caagtagaat
     6961 ggactcgcct attctcaaat tagtaatacc ttctggcata ttattattta tcaacagatg
     7021 aatagaactt gaattacctc cagatactat ttctagattt attccaaatt tttcttccat
     7081 tctttttgct atacttacca gtctgcctat attttcccta gatggtataa tagctccata
     7141 acaggttaag tttgtagcta taccaattat ttcaatattt tttaatctta ctatctctct
     7201 tacattatta aaaaagtctt cttcataaaa gtatccttct cgtaaatcgc ctaagtcaaa
     7261 cataagaact atcttatgaa taatattttt actttcacat aattcattta atttctttat
     7321 tgttcctaat tctgagttaa aactaatatc gcaataattg ataacttctt ctaattcact
     7381 taacattggg attctaatca atatcttagg tagatttata tcttgtaaat tttttaagtt
     7441 ttgtattctt gaatctgcta tatggtctat tccttcacta catatttctt ctactatttc
     7501 tttttgtgca caaaatgatt tagtaacaaa agatatctta atatttcttt catgacacat
     7561 ctgcgaaatt aattttgcat tatgctttaa cttttctata tctatttcta acctaggata
     7621 cataatcttt cctcctcaaa attcaaactt tttaacagga gcttaagaga tgcttcttca
     7681 tattttttag ataaaacacc catagatgcc ataatatagt cattatctat taatatcttt
     7741 gttttttcct ttggaaatag taattcatta tttttattgt atttgagcat attatctaat
     7801 atttcaattc tactagggag cctagtaagt gctccccctg taccaactat atatcttact
     7861 tctgttaaat ctttcccttc tgcaattttg acttttccag ttgttccata gatatttctt
     7921 atttttcctg aatgtcttag catagcttta acaacagctt cttttgtcaa tctttcaaca
     7981 aataatattt cttcttttga ttttggtatt ggaggataat tctctattac tgcatcaata
     8041 tctatagata gttcactttg taagttttct ttacctataa cttctactat attcttcata
     8101 tttacatata cacctaaatc cccctcaaca cttctctttg cagtaggttc aggattaacc
     8161 aaaattttat taatatagtc acttccatct gtaacagaat gtacatcagt agttgctcca
     8221 cctacatcca gagttaataa atctccaata tttttatata aaagtttaga agcttccatt
     8281 acagctcctg gggttggagt aatattttca ttaaccattt ctttaatgta tttcattcct
     8341 ggtgctgtag ttatgtgttc ttcaaataca ctttgaatga ttcttcttgt aggttctata
     8401 ttcaataaat ctattttagg gtatacattt tcagttatat aaagcttata attagtatct
     8461 tcaaatatta accttatttc ctcttgattt tcaacattac cagcatatat aactggtatg
     8521 cctagattca tagaagctat catttctgca ttataaatag ctgtatctct ttctccataa
     8581 tcgactccac cagctattaa aattatgttt gggtttattt cttttatttt atttaaatca
     8641 gttcttttaa ttctacctga tgttatttga cgaataacag ctccagcccc taaagctgct
     8701 tctttagctg cttttactgt catatcatag actaatccat gaacagtcat ttttaatcca
     8761 ccagctgcac tagaagttgc aaacatatca ttatactcta tatcatctac agataattta
     8821 ttagctaaat ctttaatagc acctgataag ccatttctta catcgccacc ttcaaacact
     8881 gttgttggag cttgaccttg acccaaaaat ataggattgt tagtattaat atcgtggaaa
     8941 gcgtttacca ctgtagtagt acttccaatt tcagctacca acacatctat ttttaaagaa
     9001 accttgctat tttccattat ttattactca tttctcttct tttttcaact aagaaagtgg
     9061 ctacatgtat gcctttactg tttcttccaa atccagcatc tatgccttgt tcaacagcta
     9121 tttcaggtgt tacttgtgtt cctccacacg caatcattac tttatctctt ataccttttt
     9181 ctacacaata atcgtgtaat tttttcatgt ttttatagtg aatatcatca tgacttatta
     9241 ttgtagatgc aagtattgca tctgcattca gttcaatcgc tgcatctacc aatttttcta
     9301 caggtacaga agtccctaga tagtggcatt ctatgccata tttttcaata cctccatgtt
     9361 ttatatctat tatttctctt aaaccaactg aatgttcatc ttctccaacc gtagctgaaa
     9421 ctattttcat aggtttttct tctatatctg ctcttatttc ttcatcagtt agtaccttag
     9481 gttcttctgg tattactaaa ttgtttaaat ctatatcaaa cggaactctt cctttcactt
     9541 ctattctagt cccttcagat tcatgcataa cttctctact tatgacctca atttcttgta
     9601 agttcatttt tttgacaaat tccaaagctg caaactctgc tgttctttta tcagtaggaa
     9661 gcatcattgt tatcattata attccatctg cacaccattc catttcaggc ttaattttag
     9721 ttccatttct gtactcatat gattctttta gtctattttc tacattatca aaatcgtcaa
     9781 gctcatcaat atatattatt ttgtctggat tttcaaatgt acatccatct attaacattg
     9841 atggattatc tatagcattt tcatcatatt gagctacatt attgtatcca aagtgagcag
     9901 ttacaggtgc taaataatct tcttctcttt cataaacagt accttcacca actccacctt
     9961 ttatttttct agatattcca tcaccatttc tttctggata atttccagaa tcaacaaaaa
    10021 atccttgttc cacagattca aaatatccac caacttcaga tatttcttcc atatataata
    10081 cagctctttc tttaagttct cttgctttgt ctcttaattc accgacatct ttaagttcta
    10141 tcatatccat aagcccatcc ataccaacta aagcttgctt tgctgtatca catgcttcta
    10201 tattgtatat atgccaaggt acatttctac cttcatcagg tgttatagtt gattgtatgt
    10261 cagctctagt taatactgat gttaataagt ttaatacatg agtaactgtt gcttctctag
    10321 ttgatgattc catatattta gtattcattt gagctctcat cttataatca ctaaataact
    10381 ctctaagtgc aacagcgtaa ggtaagtcta tttttaaaca tggtgctgga ggtgctgttg
    10441 gtggaactgt tgataagcat atattacttt tatctatacc tattttttct gagaatatag
    10501 agtttaaagc gtgttgaacc ataagttcag gcattacctt ccatgcttct ctagcagtag
    10561 cattagcatt atgtgctcca tcaatttgag ctatattggc aaaagccatt attttctttg
    10621 cctcacaagc atctacaaaa gaccttacca tgtttatatt cctatacaga acattatatt
    10681 gtgggtcttg atgtgctcca ttaactcctt cctcagcaaa cattactgct acttcaggac
    10741 cagcaacacc acttacatat gaatgataat taataggtct accaacttct tcttctataa
    10801 aatcaagagc cttcctttga gctcttactt gttttcttgt tattggaact ccacctatac
    10861 cttgtggggt tccttctata agcccatcaa aatgtgattg tccagcagtt ctgataacca
    10921 ttagatggtc agctccatga tgagctgcca ttctcattct tcttatatca tcctcaaatc
    10981 taccagaagc tatttcagta gtaataactg gacttggttg agggtctata ttattgaaat
    11041 acttagatga tggtagccct acactcttct ttaaaggttt tgtacagtct ttatatttaa
    11101 aaggtcccat ttcaagattt tccaagtgtt ctctccaaac ccaacctctt cgttttggtt
    11161 tatatttatc caaatctttt aatatatagt ctatatccaa ttttttattt tcctttaaca
    11221 tgattctacc ccttctctaa ataaacatgt aacttcatcc caatattcac ccttaactaa
    11281 taacaaacct gcttctctaa ccgttatatt tttagattta gccaatttat aaactacatg
    11341 ccctgctcct ttacctataa gacctctttc cataacccct tctaaaatag gttttacttc
    11401 aagagaagaa aatcccattc tcaacaagac agacctttct attgatggtg ttgtattctt
    11461 tttaccaagt tctatcattg gttctactat ctgggtagct aaactccaaa acctttcttt
    11521 taactcatca tcactcagtt cttgaagatg ttttcttcta acttcaaaat catcctctct
    11581 ttttttcatg aacattcctc cattcgtatt gatttaatcg aattttctga atttttattt
    11641 tatattaaat taaaaaacaa taattactat aaattattta atacatcaac aacaaaatct
    11701 cttgaacttt ttacttcttc cattaaaaat tctatatctc gattacttag cttatcaata
    11761 ttatcaatgt gattattaga tatacaattt tttataaatg actttcttat tttattcata
    11821 tcaatatcaa cacatttcaa taattctggt ctttctggta atattaagtt tactcctgca
    11881 atttcttctc ttggatttcc aaattttata tctattccat tttctcttgc aaaggtaagt
    11941 tgtggacata tatgtttacc tgcacccgta tattctgttt cttgtaccac tatagcttta
    12001 tcctcatcta gctcttgagc taaagagaat gctgctgcta aagatgtatt tcctgctgga
    12061 cctctttcta taccttctag ctgtgccaat aattcagttg tataaaaaac ttctccttgt
    12121 tttactaata catatctatc catatatcta agtggtctag ctgcagacct aggtacatct
    12181 gacctatcag gccatgtaca gtatggtatc ccaaaacctg tatgtcctgt tgtaaatgat
    12241 tttttattaa attgattatc actagccatg tgtaatcctt ttaaatctac acttgctcct
    12301 actactttag tattaataga accagctttt atcaatcctc ttgcagttcc agtaagatta
    12361 ccaccacctg catttgtaca aacaactata tcagggtctt ttttatactt ttctctaaat
    12421 tggatagcta actcataacc taaagtttct acacctgcaa ttccaaatgg tgaatataat
    12481 gatgcgttaa aatagcctgt ttcttctaat aaaactaaga acgtataaaa taactctggt
    12541 ccaacagtta actgaacaac ttctgctcca tatgcctcac attttcgcgc tttttctatg
    12601 atttcaggtt gacctacacc attagaatca taacattctt gaactattat acattttaat
    12661 ccctgcattg ccgcttgtga tgctacagct gcaccatagt taccactggt agctgctatt
    12721 acacctttat atcccatttg tttggcatga tatactgcag tagctgctct tcttgcttta
    12781 aaactaccag atgcattcat tgcttcatct tttacaaata ttctagctcc tttaccttct
    12841 ttagcacatt ttctagctaa tttagtcaaa tttttaagct ctattaaagg agtatttcca
    12901 acagcatact gtgattgaat tgcttcaata tcttgtaatg tatatcctgt ttcactcatc
    12961 attttctcat aatcaaaccc tattccctct tgttcaaaag aagaataatc caatccgatt
    13021 gcatttttca ttatttcgtt atttcttccc ataacagctt gataactcat atctttcatt
    13081 gatgttgaat tattcattat atacacctcc aaataatatt tctttagctt ggattcctat
    13141 ttggagtaac tctggtatac atttaccata atcatgagta taatatggat ttattttaag
    13201 taaattacct tttacaagtc tgcctgtaat tgttttaact tctactaagt cgcctataga
    13261 agcatcactt tgtataaaac ctttaaccca catttctaag gatactttct tagtatcctc
    13321 tggaacttgt ggagctcttt cttctggagt caatactata ttgtgtataa taacccaatc
    13381 attaatttta gcatccattt tttcatcccc ttattaattg actattgcct tactaattaa
    13441 tttactgtta ttttaaatta aacattattt taccaattag ctaactgtta tcttactaat
    13501 tagctagttg ctatcttact aattagcctt tgattcttct tccaattcaa cttctatctg
    13561 atttcttata tctcccatta ttgctctagg tactggtata tccaacatag ttttaagacc
    13621 tggtctagca tttattatta atggaataga gtttactatc attgcataag tacctactcc
    13681 tccaggtatt tcaggattta tttgtaaatc aatgtttggt atacctttta ttgatacata
    13741 gtctcctgtt ttaatacctt ctgcttctgg tattatctgt tgtggatgct ccatttcaat
    13801 taaaacttct ccatttacat atccatatcc acattgtcta caaccagcaa catttccagc
    13861 caatgcctct ccgtacttag attttctatc tactgtagtc attattggct cttttgtttg
    13921 ttctatctta tctaatttcc aacctaatcc atcagctatc atatttattg attctacaaa
    13981 acctacatga cctgctatag tcttatcttc tacacctttt ataaattctt cccttgttac
    14041 tccaacacct tgttccacca taacagactt tccaaatgga gataaatcat ttactctctt
    14101 agcttttata ctagtaactt cttcacaagt acctgaaagt gccaatacta gtaaatctaa
    14161 tacaaatcct ggatttattc ctgttccaag tatacttact ccattttcct ttgcaacttc
    14221 atccattttt ttagctaaat ctgcatcatc agcttgtgga tatgccattt gttctgctgt
    14281 tgatataaca tttatttttc tatttaataa gaaatttatt ttatcaaaag cctttttagt
    14341 aaatgaatca gttgctaaca aaacaacatc tacacttttt tctctaaaaa cttcttcata
    14401 atttttattg ataataactt ctggtctttc tcctctttca attcctaaaa catcatacat
    14461 acttttccct gaagtacttc tactacaaac agatactatt tctatacctt ctttctttag
    14521 aatcatatta gccataccta ttcccatagc tccaaatccc catattccta ctcttacttt
    14581 tctcatatat acaccctcct aaaaatttat atattctcaa taattagtta aagcataaat
    14641 cgtgccaact ttaaaattaa agtaaatatt tattggaacg ttgaaactat aattatttta
    14701 ttatgtattt tcataaataa aaaataatat ttcttatgag aaataaaaaa aagagcaaaa
    14761 tattttgctc ttttataata attttgctcc tctattttgc ttttttattt tactttgatt
    14821 ttgttttttt atcttgctta tttataatat tttgatatta tattttttta ttttatactg
    14881 taaattttgc ctattcatac ctaaaattga tgcagcttta gttatattgt aagatgcctt
    14941 ttctaatgat tcatatatat acttttcttc tatctcactg ataatcttac taagtgtttt
    15001 gtcctccaaa tcgtttaaag aataattgtt actctcttta ttctctttaa gagtgtaata
    15061 gtcgtttaga ttaatcatac ttgtttctat ttgtacctca tcttccatca tactcatagt
    15121 acaataaatt atgttttcta gctctcttat gttaccttgc caatcgtaat tttttaaaat
    15181 tttaatagct tcatctgaaa ttcctaccac ttttttattt aactttttat tatactttga
    15241 aataaatttt ttgcacaata gaggtatgtc ctcttttcta tctctaagag gaggaatttt
    15301 tatatgaatt atgttaagcc tataatataa atcttttcgc attttatgct cgtttaaaat
    15361 tacctttgga ctttcatttg tcgttgcaat aattcttaca tctataggta tatccttagt
    15421 tcctccaacc cttcttacat aaccttcttg taaaaccctt aatagtttag cctgtaacat
    15481 aataggcatg gaatttatct catccaataa caatgtccct ttgttagctt gttcaaataa
    15541 gcctggccta tctattgctc ctgtaaatcc tcccttgcta gttccaaaaa gaataccttc
    15601 gaatagtgat tccggcaaag ctgcacaatt ttgtgctata aatggatagt ttctcctatt
    15661 acttccatag tgaatggact ggctaaataa ctctttaccc gttccagttt caccgtatat
    15721 aaatactgaa gcatcagact tgcaagcttt cttagattta gctattgctt ctttaatcaa
    15781 attactttcc cctaaaatat catcaaattc ataacccttt ttttgtctaa tactaacttt
    15841 attgactaaa ttttttttat aatttctatt tagtaaattt tctatcgttg tcatattctt
    15901 tgatatttca agtgccccta caaactcgcc tttaatatca attggtattg tagtattaat
    15961 tgctgttatc tcttttccat ttttatccag atatttttga atattgtctt tgataacttc
    16021 ccttttttcc aaaacttcta atagtgtact cctgtttatt ttcattttgt tgactatatc
    16081 aaaaaatgaa ttggttaaaa tatcgtgtct gttcattttt tccatttttt gtacagaatt
    16141 attgtagatt atagttttcc cgtctttatt aacaaaatgt accccttcat caatattttc
    16201 caatatttca ttcattattt taaaaaatat ctcttggttc aactatatca ccccagtacc
    16261 taaatatata aaaacccaaa aaattaataa aatgttgcta ttgtatttat cttatcatat
    16321 atttatgata ttttttatgt acattatatt aatatatttt taagtatatt taaaatttta
    16381 tttatatatc tttcattatg gttatataca atatttgaat tgtcattaaa tatgccaata
    16441 gttttatata ttattgattt tattaaaaaa agagatatac aaactaataa gttgtaatct
    16501 ctcaaatata aaaaaacaat aaattagctc attggatttt ttagtccata atataattat
    16561 agattattca ccaaacaatc tatagaaatt gtggtattaa tgtttaaata accaactttt
    16621 tctaaaataa cctttatagg aatatatgag ttcataagta aagatagcga aataagaaac
    16681 cagtttggta tgtaaaatct agatttttaa ttaaattatc aagattatat attatagtat
    16741 caaaaataga aaattaaaat taaatttttt ataataaatt gtatacatta taaattatat
    16801 taaattttta atttaagtaa tagtatatgt aatctttagt catcttctta ccagtttttt
    16861 atccactttt ctaatgaagt tattttttca tatgttaatt cctcttgaaa taatgatact
    16921 aaaagacttt ttataaaatt ataacttaaa agtttatgta tttttttgat atgaatttat
    16981 agtacttatc ttctttaatt gagattgtgt atatttaact aaacattaca acaataattc
    17041 tatgaaatca aatcaattat ttacatattt ttttagaaca ataataagta tatattcaca
    17101 aaattttgtg ttaatatttt taatttgtga tataataaaa gcaaggaaac atattttact
    17161 taactttgag tgatgtttcc ttcaacaaat tattttgaag atttactttt ctggaacttt
    17221 atattaagtt cccagccact cttagttggt cgctcagagt ggctctttaa tttatcgtaa
    17281 atgtaactgg ctataacacc agttataata ctcatcatta gattttccat agttttcacc
    17341 tcctctcata agaaagtgaa gaaacttcca tggaaacacc actcatagct ttttcaaata
    17401 tttattcctt gccatattaa ttatatcata aatattggaa acataaaatt ttaatactta
    17461 tcgtctttat tattattttt tataattaat aatttttttt aataatacat aatataaatt
    17521 tatatttctt caataaaaaa gacaatctta attaattgtc ttttttaata tatatttggc
    17581 taatacatta ttttacacaa acattacaag ggtctatttt accttgtgac ttagcttgtt
    17641 ttaatgttac tttatttatt gttttacttc tttttagtgt agaacaattt tttgttagat
    17701 gatatgattt tccattagga gttacatata ctgtactttt atcagttaat ccaggattat
    17761 tagagctagg ctcattactt ggtttgttcg tattatttga attagtatct tttacaatgc
    17821 ctgtatttga atccccaaca ttattagtta tatttaaaca ttgttttata acaacatcat
    17881 caatatttcc aatagcagtt attttacttg cattttttaa tatactctta ttacttccat
    17941 ttccaactaa cactataggt gttttttgtg caattgtaga accaactaaa gaataaacta
    18001 aatcagtccc acttgctatg taaaattctt ttgagccatt ataaaattta tttattattt
    18061 gtttatttgt atcgtatcta tctactccac ctattcttgt tgctttagtt tcatttatta
    18121 acttatcact aatactgact tttccaccaa ttgcataagt ttctaatcca tctgtagcaa
    18181 aacttgtagt gtttccatca gttaatacta ttggagattt atctctaact gctatagaag
    18241 caacactcat agcatctggt tcacctttaa aagcattagt taatattact tttttaacag
    18301 cacttacact tcctatttct tttgcaactt tatgacttgt atctattcta tcagttccac
    18361 ttattctatt tatgcttatt tttttatcac ttaatatttt ctgaactgat gctcctatcg
    18421 aattttttcc tccgattaga tatacttctt ttaccttttc taatcttttt aatgtttctg
    18481 aagggattgt atctttctta gttaacaata ttggggcatt tttagctcct gacaatccac
    18541 ttgctgacaa tccatcagat aatccatttt cagaattaat aagtattgca atatcataat
    18601 tttgtttatc tgctattaaa cctgctgttt catacttatt tgtacctttt attgaattaa
    18661 tagaactaag agcgtttgat gttggacaac tagcaatcaa taatgaaaca gacatcccta
    18721 ttgccaatag tgttttgttt aatttcataa tgaaatcctc ctataaattt tataatatta
    18781 cttaaatatt ataattctac ataaaagaat attttccttt atgaaattag tttatatttc
    18841 aaaattttgt cactttttaa atctatatac taaaaaatag actatttgta acagtctatt
    18901 tcttagtata tcaaatattt atttaggttt acgtttcttt gtactagttt ttgtatatga
    18961 tattccagtt ccaggtatac tcaatgtagc tgattttctt ccttttgaat taactgacac
    19021 tctagcacct ttaacaccag cacttatacc tacactcttc ttacctaaat ttaatttgag
    19081 tcctcctcct agatttatgc ttttcctaaa gttaaatccc atagatataa ccttcccttc
    19141 tatattttaa atatttatac ttaaaattat atttgttata cacttgccat cattggtata
    19201 tctagcatct atatcttttt acgttttttc ttcttatata ctactccagc aactacagct
    19261 gctgttccag ctccaacccc ataagtagca tttctacttt tctcttcttc tcttttttct
    19321 aaaccttcat catatacacc ttttaactta gtttcaatag acttcatttc atctggtata
    19381 ctaaaatctt cttcattgta accttgatta tatacacttt cttttgcttt aggtaactta
    19441 accttaccat tatcatatcc ttctttaaac caattagcat atttaacatt acctatagtt
    19501 gatgtgtcaa atctttctcc tttgatagca ctctcaaatc cttgagtagt gtaatcattt
    19561 tttaattgtt cttgtatttc gtcataagca ttattataag catctataaa tttagaatct
    19621 atgttttctt caaatgtcat tttttcttta tctttattgc tatcctctat ccctttagct
    19681 ttatattctt ctatcttttt agtcttatat tcattgtatc cagttgaata tccggtatca
    19741 taagcatttt ttaaaacttc tttttcatat gtattattag atttagcacc tgtaagccct
    19801 agattatatc cagtctcttt agcctccttt tcttcctctt ctaatttagc cttacctttt
    19861 tcatatcctt ctgagtactt tgattcatat gtatcactat aatctccact ataatttgat
    19921 gaactataat ttcctttata cccatcttca tacccttgat tatatccttt ttctccaaca
    19981 gacctctttt gcttttcttc attattaacc gaagttgctg ttccagaact gcttcctcct
    20041 ccagtataag gacaaccacc attattatgt aaatgagctg gataaccacc acaatgatag
    20101 tgataacttc ctaatccaga tttattttta ttatcacgat gacctcctga tgaatcagtt
    20161 cttcctgaat gagcatacga aaagctccct acactaatca tagttatact cattgcaaca
    20221 gctattaact ttttcttaaa cataatctat ttccccctaa aatattctat gattttatta
    20281 tatcagtcaa tatattatgt ttaaaccgtt aaaattcgac aatgtaaata tttgatgaat
    20341 tgtatttgta aataaatctt ttagcatatc ttgaatatct gtagttgttt tgacatcata
    20401 ttcttcaata agttttttaa tatttcgttt ttgttaaaca taaaaagcgt gcacttttct
    20461 ttgtatagtg atatttgata ttttaattat cactacttta gaagaataca cactttattt
    20521 taaaaaccct gatactatgt tattagaaaa tggtactaat ataaaagata tccagcatat
    20581 actcggacat gctaaaactt caacaactat ggatacatat ttacatgtaa ctaacaacat
    20641 gagaaaccag acggtaaata tttttgaaat cattgtagaa taaatttgcc acccaaaaat
    20701 aattatggtg gcaaataggt ggcaaatcta cttttaagac acactataaa agtctgaaac
    20761 cctgttattc tctaataagt ttaactacag tctcacaatg tggcgtattt gggaacatat
    20821 ccatacactt aaccatctta atctcataac catacccctt aaaatcaacc aaatcaacaa
    20881 ccaaagactt aggattacaa gaaatataaa caatctcctt agcaccaaat ccacaaatat
    20941 ccctaatagc atccttatga atgcctggtc taggagggtc aacaataatc aaatcaggct
    21001 tgtcctttaa atccttaaca accttagcca catccccagc aataaactca caattagtaa
    21061 gtccattcaa cttagcattc tcattagcag caacaacagc ttcctcaact atctcaatac
    21121 catacacttt cttagcagca ccagccataa cctgtccaat agacccagta ccactataca
    21181 agtcaaatac aactttatca ttgtaatctc caataaaatc cctagcaata ctataaagaa
    21241 cctcagctcc cttagtattg gtttggaaaa acgaaaatgg tgaaatctta aacttaagac
    21301 ctaaaatttc ttcttgtata taatctcttc catacaatac tcttaactca tcacattgga
    21361 ctgcatctgc taaaccatca ttaatagtat gaagtacacc tactaactca gcttttaaat
    21421 caatccctaa aagcatatct ttaaactcat acatatcaaa atcttcttga gaagaagtta
    21481 ctatattaac tataatctca ttagtgtgaa tcccttttct aactacaaga tgtctcaaat
    21541 atcctttgtg attcattgtt ctataataag gaagcttttt ttcattgaaa aactctacac
    21601 tagaaactaa tatctttgag aagtcttcat caaccaacat acactcctca acagtttgta
    21661 tatctatatg ctttcctttt ttatgaagac ctaatgtcaa aggtccattt tttacttcat
    21721 ctccaaaagt atattccatc ttatttctat aatatttgtt ttctggactt ccttctatcc
    21781 ctaaaaactg aaatccaaat aaatcttgct ttaaaaataa atccataact tgtttttctt
    21841 ttatttctaa ttgtttttca tatggcacag acaatagtgt acatcctcca cactctctaa
    21901 agtgcttgca agtttcttca gtttcaagtg gtgagttctc taataattct atcatcttaa
    21961 cttcagcttt cttacttcta acttttttaa ctccagctct caccttttga ccacttattc
    22021 cacccttcat atggataact ctatctccaa cttggcttaa agatgtacca ccaaattcca
    22081 ttttatctac ttcaaattct ataacatctt ttttcttcac agacattcct ccaatttact
    22141 atagtatctt tattatcttt cttcaatcaa ttttacttct tcatctgtta actctctata
    22201 ctcacctaac tctaaacttt catccaattt taaattgccc atagacaatc tttttaagta
    22261 tactactttt ttgcctacgc tttcaaacat tctttttact tggtgaaact taccttcatg
    22321 tattgtaagc tctatttctg attcatcatc actttttaat atatttaact gtgatggcat
    22381 agttttatat ccgtcatcaa gcactacacc ttctaaaaaa gcttctacat cttcttcagt
    22441 aactactcca tcaatttttg cataataagt cttaggcaca tgcttcttag gagataaaac
    22501 tctatgagaa agctttccat cattagttaa aactaataat ccctctgtgt ctttatctaa
    22561 ccttccaaca ggaaatggtt caaaagctaa gtatgataaa tcaattaaat ctaatactgt
    22621 tgggtcatat ttatctgtag ttgctgatat atatccatca ggtttattca tcatcaaata
    22681 tatatattct ctatatataa cttcttctcc attaaataat atctcatcat tttcagtgtc
    22741 tacttgagtt cctggatttg aaacttcact tccatttact actacagacc cttgtttaca
    22801 atacttcttt atttcacttc tgcttccata acctaaattt gaaagaattt tatctatacg
    22861 ttgcttttta gccattaaaa atgctctcca ttctcataat atttttcttt ttcaaatact
    22921 gtaaatgcta aatccatact ttctacatct aaattatttc ttatactatc agttattatt
    22981 cttgctacta tatcttgtac ttcttgtcct ctatcaaacc aagctacttc aacaaaagga
    23041 tatacatctg ctattttacc atctcttatt gcaactgact ttatacattc tatttcaaag
    23101 tagtctcttg gacattttac agcttcaact aaatcattta tcattttttc acttatttta
    23161 catatatcat tttcattaat tcctcttatt tttatctgtg gcatagttta tctcctttat
    23221 tttaaatttt tagtgaatta tcatccactt aattcccttc gataacgttt gaagtggtaa
    23281 cttcttggtc aagacaacta ttgttatcag tatctccaaa ctaataaggt agttcctacc
    23341 cttatagtta gcattatata gctaattttc ctaaattgtt tatattcttt attattttat
    23401 ttaatcctat tgtcttctat ttaacattat acttgtaatt tatagttatt acaatttact
    23461 atatactttt tttgatttaa cgttataata taagtgatgg gtaaatttta aaagttaata
    23521 ggaggagttt aaaatggcat taattactac aaaagaaatg tttaaaaaag cttacgaagg
    23581 tggatttgct ataggtgcat ttaacataag tgacttagaa caattacaag gtgttttaaa
    23641 agctgctaaa gctaaaaatt cttatgttat gatacaagct tctatgtcag ctgttaaata
    23701 tgctggacct catacattag ttgaaatggt taaggctgct tctgatgaaa taggtgtaga
    23761 tgtagctctt cacttagacc atggtccaaa tatggatgct attaaaactt gtattgatgc
    23821 tggtttctct tcagttatga tagatggttc tcattttgac tttgaagaaa atgttagaat
    23881 aactaaagaa gctgttgaat atgcacactc taaaggtgtt gttgttgaag cagaacttgg
    23941 tgttctagct ggaacagaag atgatgttac ttctgatgtt cacaagtata ctcaaccagc
    24001 tgaggcagtt gagttcgttg aaagaacagg tgttgattca ttagcaatag ctattggaac
    24061 ttctcatggt gctttcaaat tcaaaggaga agctaaatta agattcgata tactagaaga
    24121 aatccaaagc aaattaccag gtttcccaat agttcttcat ggtgcatctg ctgttgacca
    24181 aaacgctgtt gctacatgta atgaatttgg tggaaatata gctggtgcta aaggtgtacc
    24241 tgtagatatg ttaagaaaag catcttctat ggctgtttgt aaaataaaca tggatactga
    24301 cttaagacta gctatgactg ctgctatcag aaaattctta gctgaaaatc caaaagaatt
    24361 tgacccaaga aaatacattg gtgctggtag agatgctata caagctgtag ttgaaagcaa
    24421 gatagatgat gttttaggtt ctgctaactc tataaactaa tataactttt aaatatttat
    24481 aaaagaaaag agatgactta aagtaattaa atttattttt aagccatctc ttttaagttg
    24541 tataaattat gtatcttata atattttaat tatattgtct ttttaaactg acagctaaac
    24601 gtgaatatgt ccactcttta tctttctatg gatggtagaa ggatatatac ctataacttc
    24661 agcagccttt gttattgaac catacttatt tatagcctta cttatcatta tttggtccac
    24721 tattttatat gcatcattaa gattcataat tccatttacc actattggtg ataaatcatc
    24781 tgtttcatta tcaatcatat ctaaatttat cagcatgtta aattcatctt ctccaattac
    24841 atttttagct gataatacta caaatctttc aatgatgttt tttaattctc ttatgtttcc
    24901 tggccaagaa tattcttcta ataactcaat aactttaggc gaaacttcta cttctctatt
    24961 gtacttttca ttgtaaagtt ttaagaaata atttactaat ggtactatat cctcttttct
    25021 ttctctaaga ggaggtattt ttactggaat aacacttaat ctatagtaca aatcttgtct
    25081 aaatttaagg ttatttctaa ggtcttcatg agaaatatta gtagcactta tatatctaac
    25141 atctattttt ataggcttac taccacctat tctagtaata gtattttctt gtataaccct
    25201 aagtaatttt ttttgcatct gcattggtaa ctcacctatc tcatccaaga aaatagttcc
    25261 accattcgcc tcttcaaaaa gtcccttttt accttttttc ttagctccag taaaagaacc
    25321 ttcttcatat ccaaaaaact ctgactctaa taattcattt ggtatagctc cacagtttat
    25381 agctataaag ggtttgtctc tccttgaact atacttatat attgttcttg ctattatttc
    25441 ttttcctaca cctgattctc catttataaa tatagaagaa tctgaggctg cagctctctt
    25501 aacaactttt tttatattgt ccataatctt actttgactt atatactctg tgtcttctga
    25561 tatatcacta tattttatct gagattcaag cttaataacc cttgaaatat ctctccctgt
    25621 tagtactcct cctgtaagct ttcccttaga atcccatctt ggaactgccg tatatgcaat
    25681 aagcttccca tctgggtaaa cgatatttct ataaatcttt ttcttcactt taagcatgtt
    25741 taatattatt ggttcttcaa ctaatccttg tctcacaagg tctgttatat ttctaccaag
    25801 tacctcagtt cttttaaaag gtaatatctc atcactgaca gtgttcatct tttcaattac
    25861 cccatctttg ttaaacacaa caacaacttc atctatatgc tctattatat cttcaattac
    25921 tttatcagat attagagact tctcaaataa ataaactata ttattttcat tattattatc
    25981 tttcatattg tatatatgtg cagtcatcct taactctctg aaagctattt tctttttact
    26041 atctgtcagt atttctgttt tgtcaaaatt tgaatctaat tcatttatat ttctaggctt
    26101 ttttatatct agaaaactaa aaatactatc tattagatga ttacagtata ttatttcgcc
    26161 tgattcttta cataaaatgg ctggattttc tacatgttct ataagcccta ttaaattatt
    26221 atccattaat attcgcacct ttcattaagt aatttattga actacataca aaatttattg
    26281 tttgcttaca ataaatacca tcagcacata taatcaactc cttataatat tcgtcttttc
    26341 aagtagttta tttcattaaa acgtaactaa gatataattt taatgattat agtttgttaa
    26401 aaatttcatt ttgcttttaa ttgtatttta tcacatattt agtaattatt tgtctattta
    26461 atacaattta attaaattta agatttattt aaaaaaacaa agataatcct tacagaatat
    26521 aactcacaat ttgtaagcaa tatacatata aggattatcc agattatctt gtattataaa
    26581 attttattca aacagacttt ttaataactg acaaatacac actagcaata acttatcaaa
    26641 gggttaataa ttatgttact aactaataag acttattcaa tcagtaatat ttatatagtt
    26701 tgtatctatt aagcttttat agcttctaat aaatcatcaa cgctatctaa tttttctata
    26761 agcattggaa ctatttcatg taagtctcca actactccat agtcagcgat ttctaaaatt
    26821 ggagctgctg ggtttttgtt tatagcaatt atgaaatctg atgattgcat acctgctaaa
    26881 tgttgtattg ctcctgatat accacaagct atatataggt ttggtttaac agtagttcct
    26941 gtttgaccta cttggtgaga atggtctatc catccagcat caacagccgc acgagaagaa
    27001 ccaactactc cacctaattt gtcagctaat ttcttaagca tttcaaatcc ttctggtcca
    27061 cctaatccta aaccacctga tactataaca tttgcatctg taagagatac taaatctttc
    27121 ttagttttaa ctgtttctaa aacagtagtt cttatatcat cttgagttat tttgtagtct
    27181 aatgctataa cttcaccagt tcttgtttcg tctttttcag ctttatccat aacaccaggt
    27241 ctaactgtag acatttgagg tctatggttt ggacaaatga ttgtagccat tatgtttcca
    27301 ccaaatgctg gacgagtttg ttttattttc ttatcttctg ggtctatttc taacttagta
    27361 cagtcagctg ttaatccagt tccaactctt gaagctattc taggtgctaa gtctctacct
    27421 atatgagttg ctccgaaaag cattatttct ggttttattt catctattgc atcttttatt
    27481 acttttgtat atgcatcagt tgtatatttt tctaaaagag catcatctgc aacataaact
    27541 ttgtcagctc caaaagtgat taattcttta gctaatccat caacatcttt tcctaataat
    27601 attgcacaaa gttctgcatc tacttcttta gctaattttc ttccttctcc taataattct
    27661 ataactactg gagctatttt tccttctctt tgttctgcaa atatccatac gtttttataa
    27721 gaacttaaat cttttatatc attcatagtt tgtactcctc caacttatat aatgtgcttt
    27781 tgttttagac cgattattat tttactagct atttcatcag ctttaccttc taagatttct
    27841 ccttttcctc ttggttcagg agtaaatgat ctaaatactt tagttggtga tgcttttaaa
    27901 ccaacttctt ctttatttac atctaaatca tcaattgtcc aaacttttac atcatgttta
    27961 tatgctttta ctattttatc aacagacatg tatctaggtg tatttaactc ttttactgct
    28021 gttaaaagta caggtgtact tacttttatt aattcgtatc catcttctaa ttgtctttga
    28081 actattatat cttttccttc tattttgaaa tcttgtacat atgtaacttg aggaatgtct
    28141 aatttctctg caatttgtgg tccaacttgt gcagtatctc catctattgc ttgtcttcct
    28201 gcaaatatta tgtcatagtc acctacttta gatattcccg ctgcaatagt atttgatgta
    28261 gcccaagtat cagctcctcc aaatgctcta tcacttaata atattgcatc atcagcaccc
    28321 atagctaaac actctcttag cataaagtct gcttgaggag gtcccattgt tataactgtt
    28381 atagttacat catcatgctc atctttaatt tttaaagctt cctctaatgc atttgcatca
    28441 tctgggttta atatacttgg aactccatct cttataagag tacctgtttc tttatttatt
    28501 cttacttcgt tagtatctgg aacttgtttt acgcaaacta atattttcaa agtctatacc
    28561 tccaatttca ttagattatt tattatttta atacgtttga tgaaattacc attttttgaa
    28621 cttctgatgt tccttcgtat attgatacga ttctagcatc tctgtacatt ctttcgattt
    28681 cataatcttt tataaatcca tatccaccgt gaagttgtaa tgctttataa gcaacttcat
    28741 ttgcaatttc tgatgcatag tatttagcca tagcagattc ttgagcaact ctcattcctg
    28801 catctctctt ttgtgctgca tcataaacta atcctctagc tgcacaaact tttgtttcca
    28861 tgtcagctat agtaaattga gtattttgga atttagctat aggcttacca aattgaactc
    28921 tttgttttgt atatttaaca gcttcatcta aagcaccttg agctattcct agagctaagg
    28981 cagcaacacc tattctacca acttctagag tacccattgc tatcttaaat ccttgacctt
    29041 cttttccaag taagttttct tttggaactt taacgttttc aaatattaag tcagaagttt
    29101 cagttcctct tatacccatc ttatcttcat gagctcctgt tgagaaacca tcccatttac
    29161 tttctactat aaacgctgat gttcctctaa gtcctttact tctatctgta actgctatta
    29221 ctatagctac atcacagaat ggtccattag ttatgaaagt ttttctacca tttaatatat
    29281 agtggtctcc aactaattct gctgttgttt gttgtccacc tgcatcagaa ccagctcctg
    29341 gctcagttaa accaaatgct cctattaatt cacctgttgc tatacctttt aagtattttt
    29401 gtttttgctc ttcagtacca ttgtaaagta ttggtaatga agcaagagaa gaaccagctg
    29461 taacaaaagt agctgttgaa gcacatcttc tagctatttc ttccattact atagcgtaag
    29521 aaacatatcc tgctccccca ccaccatatt cttctgggat attactgctt ataaattttg
    29581 catcagctaa ttttttgatt aattccttag gcattacacc tgttttatcc atttctgctg
    29641 gtaaagtatc taattcttta ctaacaaaat ctcttactgc ttttcttaaa agttcttgtt
    29701 ctttgttata taacatagct tcctccaatt ttcatatttt atagtaaatt tattttaatg
    29761 aacttacgct aaactcatca tctcagcaaa agtttgaata cgagttctgg cttgttcatt
    29821 attctgagtt tgttggtcga tttcaacata taaagtaggt attccactat cttctatatc
    29881 ttttctaact aaaggataat cgtattcttc tgggtcacag aatttcatca tacagaagat
    29941 aacaccatct atatctttct ttttaacttc atctactata agtgacccac gttttttctt
    30001 agggtcataa gctaatgaac atccttctat gtttgaccat tgtcttgcta atctctctaa
    30061 cgcatcatca cctgctggta catctgttct gaattgtctt gtttcttgtg ctaagtcgtc
    30121 agctacaact gatatattgt tgtcttctaa aatgtctaat atatctttag aatcagctaa
    30181 tatacctgtt aataaaactt tctttccaga acagacttct tctggcatag catttaattt
    30241 tgctattaaa tctttcacta gctcagtatg ttcttctttt ctcataaaga acccactctt
    30301 aattactaag cttcttattg atggttttat agtattagaa tgtttataag ctacttcaac
    30361 aaagtctctc atagtttttc tatgttcatt gtaaacttct atactttcat gaatttttgc
    30421 ttcttctatt tcatatccac aaatttcttc aagttctctt tttacacctt tgtactcact
    30481 gattaagtat tttacaccag cttcaagttt tctattttgt gggtgtacta atgatatata
    30541 ttttatatga ggtactgctg atttccagtt ttgtcctaaa caaattagtg tatcacacat
    30601 acctggtata ataactccag ataattcatc ataagcacct tttaatccat attctaaaca
    30661 tgattgcatt attgaacatg caaatgcagg gaaatattgt ttagctaaat ctaattctgt
    30721 ttgtcctccc catataccaa ctggaagcat tccagctgca tgtataattt cttctgggca
    30781 ataaactggg aaacaaccta tagctttttt accagtttca cttttatatt tttttacagc
    30841 cgcatttgga ttttcaacta cttctttcat tttagataaa atagcttcca ttatatctca
    30901 cctctattaa gtttttttct ttcttccatt acttcaacta aaccttgaat tcttgtttca
    30961 aattgagcat tagtgaaagc tctagggtct gcttggtcac catcaaatcc agcatatggt
    31021 aatccagttt cttcagctgc tcttctttgc atttcatatt gtattaaact cataagttta
    31081 cagcttctgt tcatatgata gaatgctcca tcacatttac cctctactaa agaatcaact
    31141 ctatattttg tcatacggtc taggtttaca ttgttaaaca tagtactata tgctactgcc
    31201 attccatcta aatcattaac ttcatattgt aatgcccaag catgtgggta aacactacct
    31261 gtcatgttaa ctccaaattt agctaatgtt ttcatcttgt atcctatata tggccaacaa
    31321 ggtatacctt ccatcattat tctgtatttt tcttcccctc tgaaagaaga tttaccagtt
    31381 ttcatgttgt cctctaattc ttctataagt aacttaaatg cttctgtagt ttctttttta
    31441 cctctagcac aaactattac agccatgtaa gtaaataagt caaatccatt cattggagaa
    31501 ggagaagaat ctgctggtaa actcatagaa tacttccata gtcttccgtt ttcagctgat
    31561 attttcatta cttcttcaaa cttcttaggg tcaaatttct ttcctgatat aatttctagt
    31621 tgttttatag cttcttcaaa ttgagcttta atataatcta ttcttgattg agtaacttcg
    31681 tcttcattat tgaaagttgt atcaatcatt attaaaggta tatctaattc tcttgaaata
    31741 ttttcatacc attttataac ttggttacat atattgttac agcaaagtag gaaatctgga
    31801 gccggcatat ccaaagcttc acatccacca ttttctaaaa gaccaaaatt tgttcttgca
    31861 tatgcacata ggtcaataga atatccttta gattcagcta tttcacataa ttctaaagaa
    31921 ccttttttag ctgctactcc agctgcttgg ttttctggat ataatacgtt taagtcaaat
    31981 acttctgcta actcttgagg aaatactgat gttgaccaac ctacaggtct tccttcttct
    32041 ttagctttaa atgcatttgc atattgttca gctaataaat cattaattac tactctagct
    32101 tctttttttt cagacatttt catccctctt tttatatatt tttcacttct ttttgtgatt
    32161 cttttgcttc atcaaaagca tataacgctg ctcctaaagc accagttaat tgaggtatat
    32221 caggtacaat aatttctgtg ttgatttctc ttgccatagc tcttacaata ccactatttc
    32281 tagcaactcc accaaccata actacatttc tttgtactcc tattcttttt actaggctag
    32341 aaactctctt tgctactgaa gtatgaatac ctgccactat atcttcaatt tttgcatttt
    32401 cagataaatg tgatataacc tcagactctg caaatactgt acatgtactg cttattgata
    32461 cttcattttg agaattcata gatatacttc cgagttcaga tacatcaacc tctattattt
    32521 ttgccattac atctaaaaat cttcctgtac ctgcagcaca tttgtcattc ataagaaagt
    32581 ttaatagtct tccattatta tctaatttta atacctttgc atcttgacca cctatgtcaa
    32641 taatggttct tgtctctgga attatgaaat ttacccctct agcatgacag cttaattcac
    32701 ttatttgctt atcagcatct gaatagttca ttcttccata tcctgtaact acaacttttt
    32761 taatatcttc tcttgcaaga cctgtcttgc catataattt ttctaaaact cttgatggtc
    32821 cagtagtccc agtaccagag gatattgttt cagaagctac aatatcttcc ccattcttta
    32881 agattactcc ctttgatgca gttgaaccta tatctaatcc cattgtgtac atctttagca
    32941 ttctcctttt aaaaaatcta gaattactaa ttaatatctt acaactttac tatctttaaa
    33001 gttatttatt ttctcttcat cgtagcctaa agattttaat acttctacag tatgttgacc
    33061 tacttttggt gctggtgtat attctttaat tccttcattt ctaaacataa ctggagtatt
    33121 aactaagaca cctgtatttc cgctatcgta tgttttctta aataagaagt catttgccca
    33181 agcttgttcg tcatctaata aatcttcaca gctttgaatt ttttcaaatg gtaagtctgc
    33241 ttcttctaat aaagctgacc actcgtctaa tgttttttct aacatagctt ctccaactat
    33301 cttaactaaa tcttcaacat gattaaccat tgaatctatg ttattatatc tatcgtcttc
    33361 taatatatat tctctattta taaccttaca gaatttgcct aaccacttgt tgtattgtat
    33421 taaagctaat tgaatccatc ttccatcttt acatttatat gtagtcatta atgggctgtt
    33481 tggattttct cttgataaag gcatttcatt tccgtattgt gctgttgtta tcattgttcc
    33541 cattccatat atagctgtat ggaaaagact tactgttact ctctcacctt taccagtttg
    33601 agctttttta tgtaatgctg ctaaacttcc tgctgctagt gctagacctg catagtggtc
    33661 accaaatcct gctgctgtat ttgctggaga tgttcctttt tccataacag attggctaac
    33721 tcctcctctt gcgaagtatg cagtatagtc aaatcctggt ttatctttta aaggtccttt
    33781 ttcaccatat cctaatattt gagagaatat taatcctgga tacttatctt ttatttggtc
    33841 ataagctata cccatttttt ctaatgcttg aactctaaca ttagttacaa atatgtctgc
    33901 ttctgataat aatttatgta atatttctac tccttctttt gattttacat taatacttac
    33961 acccttttta tttccatttt ctaattcaaa catagggttt tcatcatctg atgctggaga
    34021 tttaaatgtt ccacccataa ctcttattcc atcaccttct ataggttcaa tcttaataac
    34081 ctctgcaccc cagtcaccta acatttttgc acaacatggt gctgcgatga aacttgaaag
    34141 ttctactact ttaactcctt ctaaaagcat aacgttttcc tccttaatag tatcaattat
    34201 aaaatttcga ttaaatcact cataaaatac ttttttctga tattaactgt ctgatgtcaa
    34261 agttcctaat cttatctaaa ataacttaaa aattattaaa attatttttt attgttttat
    34321 tgtcttacac ctatattgtt aagcatttat cgtgccaact ttatatttaa tcaaaatatc
    34381 gcttgatttg aatgtttttt aacaatatgc aattgaataa tctttttcat atcgtggcat
    34441 cttgccacta tccattgcat tttgctattc tttctatgct tataaaagtt ttttttatat
    34501 atttttttat gaaaaagctt gacatttcaa aaaaagtttt cattgctaaa ctcaaaaaca
    34561 catgttatca ttgtaattaa tcagcaagtt agttaactaa tttcaaactt agataatttt
    34621 ttaataatat ttaatctaaa aaataacaat ttctttgata aattttagag taattattac
    34681 attaaataaa aaattactaa atatcaaaat aacacaggga aaacaatttc aaaactaaat
    34741 ttttaacctt aaaaattttg tataaaaaat ataaccttat atgctacata ttatttctaa
    34801 atgaaaaatt accataataa tttaataatt acaggagggt attgatatga aaatactagt
    34861 atttggagca cgcgattatg aagaaccagt aataaaaaaa tggtctgaag aacataagga
    34921 tgttcaagtg gatatttatc ctgaaaacat gactgaagaa aatgtagtta aagctaaagg
    34981 gtatgatggt atatctatac aacaaactaa ctatatagat aatccttata tttatgaaac
    35041 tttaaaagat gctggggtta aagttatagc ttcaagaact gcaggggttg acatgataca
    35101 ttttgattta gttaatgaaa atggacttat cgttacaaac gttccttctt attcacctaa
    35161 tgcaatagct gaattagctg ttactcaagc tatgaacctt ttaagaaaga ctcctctagt
    35221 aaagaaaaaa gtctgtgaag gtgattaccg ttggatagct gaacttcttg gaacagaagt
    35281 tagatctatt acagttggtg ttataggtac aggaaaaata ggtgctactt ctgcaaaatt
    35341 attcaaaggc ctaggagcta atgtaattgc atttgaccaa tatccaaata gtgatttaaa
    35401 tgatatatta acttacaaag attctttaga agaccttcta aaagaagctg accttataac
    35461 attacatact cctttacttg aaggaacaaa acatatgata aataaagata ctctagctat
    35521 aatgaaggat ggagcttaca tagtaaatac tggccgtggt ggtttaatta atacagggga
    35581 tttaatagaa gcactagagt caggaaaaat tagagctgct gcccttgata catttgaaac
    35641 tgaaggattg ttcttaaaca aaaaaatgaa tcctggagaa ttaactgacc cagaaataaa
    35701 taaacttctt tctatggaac aagttatatt cactcatcac cttggtttct tcactagtac
    35761 agcgattgaa aatatagttt attctagttt aagtagtgct gtagaagtta taaaaacagg
    35821 aactgctact aatagagtaa attagtattt tataaatata ttttttcatt aattagctat
    35881 tatctaacaa aatagccttt aatttcccaa atataagaga gtcagctcag tatatattga
    35941 gtagactctc ttatattatt ttttatatta aacttgtact cttcttattc ataccaaatt
    36001 aaatttatat taacttactc taactactcc tactctatac attttaccta tttttacttt
    36061 tctaattata tacatttgaa tgggtacaat ctgtatttta caaaaaaaac acctaacaaa
    36121 ctatgaaaat tgtatgatta atattaatat atttataaga aaacataaca attatgttag
    36181 ctctggattt ttagggaggg agtatattgg aaaaaatgaa taaagttact tctaaaaaaa
    36241 ctacctatat tgttacttca gcattatttg catccataat atgcctgaca atagcatata
    36301 tattacatat tccagttggt ggaaacaatg gatatgttca tataggagat gcttttattt
    36361 atctagctgc aactattttg ccaacaaact atgctatagc tgcttctgca attggtgctg
    36421 gtctagctga tttatctaca ggtgctgcta tctgggtaat accaactata atcataaaac
    36481 caatacttgt attatttttc acttctaaaa gtgacaagat aataaataag agaaatatag
    36541 ttgcttcggt tgtagcaggt atagtaggat tagttttata catgtttgct gaaggtataa
    36601 ttattggaag ttttacaagt gcatttgtaa tgagcttact tggcttatta cagccaatag
    36661 gaagttttat tgtttttata atcttaggta tggcacttga taaacttgat tttaaaaaac
    36721 gttattttaa ttaagaattt aaatttatgg agggaaaatt atgaatatct tatatacaat
    36781 tgaaaatagt atctatgtaa atataactaa tacatgtcca tgtagttgtg ttttttgtat
    36841 aagaaacgaa aaagatgaag ttgcaaatag tggtagttta tggttggagc atgagccaag
    36901 tgtagatgaa gtaaaagaag ccttcaataa atacaattta gacgactatg atgaaatcgt
    36961 attttgtgga tatggcgaac cattaatgag aataaatgaa ttgatagagg tagcaaagtt
    37021 tataaaagaa aaaagtagca taaagataag aataaataca aatggtctaa gtgatttaat
    37081 acataacaaa aaaacagcta ttctgttaaa aaatgttata gatgcagtat caataagtct
    37141 taatgcccca aataaagaag cttataatag agttactcaa ccaaagtttg gagaaaaatc
    37201 atttgattat atgttagatt ttgcaagaga ttgcaaaaaa tatataaaag aagtagcttt
    37261 ttcagtagta gatgaaatat ctccagaaga aatagaagaa tctaaacaac tggcaaaaaa
    37321 acttgatata ccattaaggg ttagacataa gaattagcaa gtaaaattat aaaacattaa
    37381 gaatcacctg aatggtcttt caggtgattc ttcctcttgt attaacattt tacaaaatag
    37441 atttcatacc acactaggaa tgtgtaaatc atccaaatct ttctccaatt atcagagttt
    37501 ccactaatgt agtcattaaa aatctcatta atctcatcta tgttaaagaa tttatctgct
    37561 atctcactat tgaatttatc tcggatatcc ttattatatt ggtcatcagc catccatata
    37621 cgaattggca caataaatcc taatttattt ctaaaagcaa tctcttctgg taatgttttt
    37681 gatgcagctg tacgaaaggc aattttattc tcttttcctt tcactttata ttctgatggt
    37741 attctggatg caatatcaaa tattcttgta tctgtaagag gcattctgac ttccaatcct
    37801 actgcagtac tcattttatc tatattaaaa taaatatctc cttccaacca tatttgaata
    37861 tctacatttg acatgttagt aagtgtatct agttcttctg tttcttcata aattcctttt
    37921 accacttcaa taggaagcac atcaggattg tatttcttaa gaatttttct tttctcaccc
    37981 tcattcataa tgtttgtatt tccaatataa aatgtcttca aattctctcc ataacactct
    38041 gccttatggt atatattata tccaccaaaa aactcatctg ctccttctcc agagtaacag
    38101 atatttgtgt tttcagctgc tgccttgcat tcaatagcaa aaacgatagc agatgcatct
    38161 ccagttggtt gctccatatg gtacattaca taaggtactg acgcaaaata ctcttcaggt
    38221 gtaattatat atctcgaatt tttacaccca agaatattag ctgtctgttg tgctaatttt
    38281 gattcatcaa aacgctcttc ctcataacca catgaacctg ttttttctat atctgacatt
    38341 gccaatatat aagatgaatc aacacctcct gataggaata actctgcagt ttcattctct
    38401 gattttacct ctggcataat tttctgaagt gttgtatgaa tttcatccgt ccattcctca
    38461 atagacttgc tgtggtcagg atgaaattca ggtttccaat aacgaccaat acatactgtt
    38521 ttattctgat agacaaggta atgtcctggc ataagcttct ttactccacg gaagaatgta
    38581 ttttcacctg ctacatatgt gaaagacata taaatctgta acatgtcttc atttaactct
    38641 ttcacaaatc ctggttgctc cataatctta cgaatagatg aaccatagag aagcttccca
    38701 ttttcagtct cataataata gaaaggtttt accccaaact ggtctcttag gcagaagagt
    38761 ttcttttcca cagtatccca taatgcaaaa gcaaacattc catgcatgtg atttgccata
    38821 tcatatcccc atgtcttata tgcttccact aaaattgctc gttcacgctc atctctacat
    38881 aatgaagaat cgattccaag ttcttcacaa agaactttcc agtttcgaat atgcccattg
    38941 tattctagaa tttttatcat atatgtgtct tttcgtgtta aatacttttc ttctaaattt
    39001 atcatatgtg tatcctttcg tattaaaaca tttaacttct aaatttatta aatgtttata
    39061 tatatttatt cacttataat cactgaaaaa tcgacttttt tcaaagtaaa ttctttttga
    39121 attagtacta atctgctctt tattaatggc ataaatatga ttatcaagta ttatcagtgt
    39181 tataacattg aattttttat tcttcataaa tattgccccc tttatattac caactaaata
    39241 taatatatct tatgttactt acatattctt taagaaattc tgaagatttt ataaagtttt
    39301 ttgtattata attaattaaa aataaaattc tagttataaa acatattttc cattaaacaa
    39361 aaaaatagtt aaaataaatt cataaccaca taaacttatt ttaactattt gtatatttta
    39421 attataaata ttaacttaaa tttttaacag gatacactca taaaataaac ataatgaaca
    39481 acaaaataat atgtctcagt ttctttatat actttacctt ctttcaattt tctaccatgt
    39541 agacgtataa gataatatta gtaattcact ctattgctta actcgtgcga tatggacaac
    39601 caagaaagct atttcctcat ttgttaactt ttttccatat ttcttttcta aaaaatctct
    39661 aacttttaat gcaattaaca tttcttttgg atttgacctt ttcatttgat taaataataa
    39721 atcatcacca ctgcttaaca tactatctga aaaaaatctt tccacaaaaa attttatatg
    39781 tgttataaat ctcatataat gcatactctt tttatctaag gttctattca aagaaaaaac
    39841 aaaaatatta attatttctc caattacttt ggcatactta atcgtatcat atgaatttcc
    39901 atctgaagcc atagcatttg caaaatggaa agcaatgtta gctgcttctt cctctggtaa
    39961 ttgaatgccc aatctctcct ctaccatata aattgcaacc attccaacct taaactcatt
    40021 tggataataa ttttttattt cccaaaatac tcgatttgta atttttattc ctttacgcat
    40081 cctttcaatt gcaaagttaa aatggtctgc taatattaag tataagtttt tattaaaaga
    40141 tgagttcaat aacttttctg cctctactat tatttcctgt gttatcttta aaatgtcgac
    40201 aggaatatca tccattaatt ctaaaaattg ttttgatttt gtattttcaa cagggacaaa
    40261 catttgatta tcattggaac cacaaatata ttctcctgtt tttttaccat atccaattcc
    40321 tttccctagc aaaataaatt cattatcctt tgtgtcatga actaaaacaa cgctcgagtt
    40381 caaaactttc tttattatgt agttcatttt atttgctcac cttctattgg tcatttaaaa
    40441 tctatactat tactttcaat taccttttta taccaataaa aactatcttt cttatatcga
    40501 ttatatgtcc cctttccata atcatcagca tccacataaa tatatccata acgttttgac
    40561 atttgtttcg ttgattcact gaccaaatca atacaacccc atgaagtata tccccaaagt
    40621 tcaacaccat cttcaataat cgcatctaac atacatttaa agtgttcttt taaataatta
    40681 attctatatt ggtcatgaac ttttttatct tcagttaaaa tatctttggc tcccaatcca
    40741 ttttcaacta taaataaagg ctttctgtat ctatcatata attcaatcaa agatatacgt
    40801 agacctattg aatcaatttg ccaaccccat tcactcattt ctaaataagg attttttaca
    40861 gctaataacg tattcccagg tgtaatatct aatccagttg tatcagctgc ctcacaagaa
    40921 gacatatagt aagagaatga aataaaatct actggatact ttttcataat ttcatcatca
    40981 tgttcttctt ttactatttg aatgttatta tttttaaaat acgacagtaa atatactgga
    41041 tactcaccaa aaacctgcgt atcactatat gcataaatac ttctcatttt tcgttgagtt
    41101 gccaaaacat cttctggtct acatgtgtat ggataatacg ttaattttgt taacatacac
    41161 cctacttttg aatttggaat aatttcatga caaatttttg ttgcaagggc actagctaca
    41221 aattgatgat gcatagcttg aaaaataact tcctcaaagt ttttatcctt aaaacggtct
    41281 cgaactaaac caccagtagt gtacggatga cgaatcatag aatcaacttc attaaatgta
    41341 agccaatatt tcactttgtt tttatatctt tcacagatag tttctacata cctaacaaac
    41401 atattgataa cttgtcgtga ataccatcca tcatagttta aaacgatatt taatggtggt
    41461 tcataatgtg acatagtaac aagtggttca attccataac ttatcaactc atcaaataca
    41521 tcatcataaa actgtaaacc ttcttcattt ggctctttat catctccatt tggaaaaata
    41581 cgagaccaag caatactcat tcgatatgtc ttaaatccca tttctgccat tagagcaata
    41641 tcttctttat agtgatgata aaaatcacta ccatgacgtt ttggataatt tacttcatct
    41701 tcaggatgtg ctaatccttc ttctatatct tttgttgtga tttcattatt agatttataa
    41761 tctttcacat ctgcatcaaa gtgtgccttt gctacatctg atacagacca ccctttacca
    41821 cctaaattcc aaccaccttc aaattgatta gcagctgtag ctcctcccca aagaaatcct
    41881 tctggaaact ttctcatatt tatattcctc cctttacatc aaacaagata cttccttttt
    41941 ttacattgcc ataagactgg tttaacactt tataagcata atctgctcca ttattgttta
    42001 caatcataac agttgaatct aaattagcat gtgagatttt gtctaaatca aactgaatta
    42061 ataaatctcc ttcttttaca ttatcgcctg tcttaacaaa tgttttaaat ccatctccat
    42121 tcatacttac agtatttatt ccaatatgaa tcaaaatctc agccccattt tttgttctta
    42181 aaccaattgc atgttttgtt tcaaataaca tcacaacttc tgaatcacaa ggtgcgtata
    42241 aatttccatt ggtcggtata attgcaactc catctcccaa agtcttactt gcaaatagtt
    42301 catcattaac cttacttaaa tctattactt ttccttctac tggagttact aagatattta
    42361 cttctttttc ttcttctagc tcttcttcaa caacatctcc aattgatgac tctactgtat
    42421 ttgtatcttc cttccaaata atcagtgtaa taataaacga gcctaatatt gcaataacaa
    42481 aaccaatact tgcaaaaatc aaattgtttc cattgtttgg gtcaataaac atactcatac
    42541 tggcaagccc tggtccaaca attacaaatc cttttactgc aaataatcct aaaaatgtac
    42601 cagaaattgc acttgagaat acaacaccta acattgctct tttatgttgt aaagtaatac
    42661 catataaagc tggctctgta attcccatca aggcagaaat tcctgcagat aatgctgttt
    42721 gttttaatgt ttcatctttt gttcgcaagg ctactgcaaa acaagcacca ctttcagaaa
    42781 tattgtgggc taatgaagat gtcatatata aagcttcata acccaacttt ccaattgtat
    42841 taattgaata aggtattagt gctttgtgca ttcctgttgc aaccataaat ggaagaaaag
    42901 cagcaagtaa tcctacaact aagaatccca ttttgttata taagaataaa ataatggttg
    42961 taaaaattgt accaacgtta tatcctaaag gacctaaaat agttagagta attggaacag
    43021 taattgccaa agacatcata ggaacaaaga aagttcgaat tggttttggt gaatacttgt
    43081 taaaaatttt ctccattgtt gccaagaaag acacacataa gatagccggg aaaacctgtg
    43141 cattataggc aatgtttgga attgtaaatc caaatagttc gacaccttca cttaaagcag
    43201 ttgttgttgc tggaagcaat aagtatccta cagcggcaat agctactaaa cgattacatt
    43261 tcaatacatt ggcagtagtt acagctacca taagaggtag gaaatagaat gttgcatctg
    43321 aaatagcaac taataatgta tatatagtag aatctgattt taaaatatta aacattgcta
    43381 ataacatcaa cagtgatttt aaaataccag ctcctgcaat agcaaaaatc agtggttgaa
    43441 aaatattaat aataaattct ataaatcttg ttcctaagtt tattttttct tcagttttta
    43501 cagtactatc atttgtatct aaagggcaaa cttttaaaat ttcatcatac acatcaacaa
    43561 cactatttcc aatgacaact tgaaattgtg ccccattaac tatactcata acaccttgta
    43621 ctttttttaa agcatcctga ttgactttac ttctatcaat caacttaaag cgtagtctag
    43681 ttgaacagtg ttctaaagct aaaatatttt ttgaaccacc aacttgttca ataatgtcaa
    43741 tggcagtttt tttataattc atcttgtaat ctccttctcc ataatttttt atgaatggcc
    43801 attcaagatg caaaaaaggc agaacctata taaacacctt gaaaaatcaa agcaatatat
    43861 tcgatcctgc ctgcattacc agtaacatgt cttctattta tactattttg tattattata
    43921 ttaacatttg cctaaaagaa ttgtcaatac ttttttaaat tttctgatac taactaatag
    43981 cacctttata attcattttt tatatcaatt aaagtaacag tagccaccca ccaattagta
    44041 tcaaaattga acctggtatt ttttctttta tattttcttt gaatataaaa tgagcaagta
    44101 ttaaagttat tatcatagat acttgagaaa atggctctgc tatactaagt tctagattat
    44161 ttaaagcaat taataatgct aaataagaat atccattaat agcaccactt aaaattgaaa
    44221 gccccttttt attactaaaa atctcacaaa ttattttttg tttcttttta aatgctaaaa
    44281 agataaataa atttaaacct acgaaaaaat acagtatagt tgaatataat ataggagata
    44341 cttgtacaaa aaaagcctta tccaatactc ttcctactga ctgcaaaaat atgtataaaa
    44401 acattaatct acatggtaaa ttgttaaaaa ttacagagac attctttaaa aaagagctta
    44461 ctttttttaa tataaacact ccaccaatca taattatgat tcctgcaact tttgctaaac
    44521 ttaaaccttc acctaaaaat ataactgata aaagcagtaa aaacaatgaa tttaaactat
    44581 ttattggagt aacaagtgaa acttccccag ttgctaaaga cgttacatac gctactgaac
    44641 caattgaata gactaaacta cttatataac atggtattaa aaacgaccaa tcactaactc
    44701 tatccattat gctaaatgga agtaaacata ctccccctat aaagaaaaat agaaatgatg
    44761 aagctatatt tttataaata tctccttctt catcacctaa taatcttaca actactcttt
    44821 caaaagctaa tagcactact ctaattaata atgcaaaata agataatatc atttttgacc
    44881 tcgcttaaaa attaatccga cttattgtta tattaactgt ataaaactac catataggta
    44941 agtcttttgg attttttaat attttatgtt taaatacagg tacattaagt ttttcaccta
    45001 gtttacgaca ttgctcttta taggtacctt ttaatttatc atgaaaaact atacaatcaa
    45061 ttcctccttc aatactattt atacactttt ctagtttctc aaatccagat tcatcatcat
    45121 acattccact tacaatccat tgatttggca atacatgtcc aattgatatg ttatattctt
    45181 tattttttat aatatctgag aaagatttct caaaatgtac ccctccaaca cataacaaag
    45241 tcttcaaagg ttcatcacaa tcaaatactc taattaatga ttttgccaat acctgtattg
    45301 ctatactatt attaaaacta tcactactac ttcctatctc aatatccaac ataggtacag
    45361 aatattctgt aattaattta gattcttcac catatgttgt tccagaccag tgagttgctt
    45421 ctgttaatgt agtaaattca tcaagtagat tttcattttt tatatcctca atagcattga
    45481 ttagattttt aaagtatctt ggatttgaat ttccaaattc tcctgttgga acatctccaa
    45541 ttgtatgagc tgttaggata tgttctggag cattttctcc ctcatgccaa tttacaactc
    45601 ctgcaaaatc ataatctcta aaatgtctat ttaaaattgg aagataatat ttataattat
    45661 gacttattac atcttttgtt tttacaaaat gaaataagtt attgttttta tccttaaact
    45721 ctaatacaaa attatcatca ataacaatat cagtttgatt taaatccatt atttcttcac
    45781 aacattttat cacattactg gctactgggt ctttctttaa atcactgcaa aagaaaaaaa
    45841 ctgctttttt attattcatc cataaatcac actcctataa cttaaatata atatatcttc
    45901 atacctaaaa tcatctaaat atcactctaa ttccattaaa ttatttatat ataatatact
    45961 accatactca ttttagctat acctttgcct gagtttctat atatatgtga tacatcagct
    46021 ttaaatctta tagaatttcc actagataca atgtaatctt ctccatttat tttaatggtt
    46081 acttcgccac taaaaacagt tataaactct tgtgttcctg gaagttcagc atttgaatct
    46141 aaatttccac cttcttctat ttcaatcata aatatctcaa atcttctttt ggagtcaaat
    46201 ggaaatattg gataacttat atactttcca ttatcttcaa taaaatggtc tatatcactt
    46261 ttttgaatca attctatgtc actttcctgc ctctccatca atgatgtaaa tgagattttt
    46321 agcccattag ttattttctt caaagtagat atagtaggat ttacctcaca cttttcaatt
    46381 tgagatagca tactcttact tacaccacta agttgtgcaa tcttgtctaa actaagatgt
    46441 ttttctttcc ttatcttttt taaattttca gcaattattt catttaaact ttgcataaat
    46501 accccctaat acatactaat ataagataaa ttattttgat tattaaataa acttagtaat
    46561 ttaatagaaa ctttttatcc attataatgt acattatgtt taatatacat tacttttttt
    46621 agaatgtaaa tagttttctg aaattttgtg aaaatgaata aataaaaaac tagtaaccta
    46681 tatttttaca aggttactag cttttattat aataatcttt cattttaact ataaaactta
    46741 gatgcaccta taagctgtct cttagaaaca atcttagcta ggtttgctaa tgaagaaatt
    46801 tttatatctt taaaagaaac taaaaataca aacttaaaat ctgtaaattc ttgatttata
    46861 ttgtatatat caaaataaca tctcaaatta tcaaataagt aattatcctg taagtctgct
    46921 tctatctcat cagtagcatc ttttaaatac gctcttacat cttcaaataa aacactgaaa
    46981 taagactcat ctatttcttc acctaactct tccaatattt cttctatatc taaatcatcc
    47041 atatcaaaag aatttcctgt caactggcaa tcaaatacca atatattttc ttgatttata
    47101 gtatttgata tatcttgtac atattcgaag tctggacgta attctaaaat gtcttttatt
    47161 tcactgctct ttacatggat ttttcctttt ctattttcaa tttttaaatc tatcatatgc
    47221 tccccctttc aatctacaaa tctttaaata ccttgtttta taatcttttc aatatctatc
    47281 caattactaa ctctaactat attttgatgt ttaacatctt tattatagtt agtatccaga
    47341 agtattactt taacaccatc atcagctagt tgcactgagt ttaaaggatt atcttctata
    47401 aatatgtcac aactcagttc tcttgccttt tcaactttat aatcacttcc taataagtaa
    47461 acatctatat ctgaaaatcc ttgtctcgat agccaatttt tagttacatc agttaaacac
    47521 tcatgtctag ccgttacaaa agataaatta tgtcctttag ataatgtgct aattacctct
    47581 gtagcaccct ctacaatctt tgcttcatca tatgagtgta tatacttatt attaaactcc
    47641 gcatacacat ctcttattcc cgaaccatac aattcttccc aattatgtgt tatacactct
    47701 gcttcagtta tatttttatt aaagatatca tttaggtatg gaagaaaatg ataagggctt
    47761 gttattgttc catctatatc aatacatata ttcaatttgt tcatttttac ctccatgtaa
    47821 catttattga tttgattaat caaatattat agcacagctt taattataaa tcaaaactct
    47881 ggatatgact atacctatat aataccaaaa agcttgcata tttaagcaag cttttcgtaa
    47941 attttacatt tttaactaat atataagttt ttctaaggtt ggttccactc caaattgtga
    48001 tttcagttct ttatattctt ttaatgcttt gtcattattc gttttagttt ttatcgctct
    48061 tatcattaaa ttttttggtg tatcaagtgg agatatgtat tctactacag aagtatcata
    48121 tccattgccc tccaataaca atgttcttaa accatcagtt attaaatctg caaatctagc
    48181 tttaaataca ccatgtttta atattggttc catagcttca tatctatatt gccctaatag
    48241 ctccttatga caacatggta ctactactat agcttcagat tttgctctaa ttcctagacc
    48301 tattgccata tctgtagccg tatcacaagc atgtagactt attacaaggt caacatccct
    48361 attaggtgta taattagtca aatcctcttt tataaatgac atatttttat aacccaagtt
    48421 tttagccata ttttttgatg cttctataac tacatctgaa taatctattc ctataaaata
    48481 acagtttttc ttcaatactt cttttatata aaaatttaag acaaagctta agtaggattt
    48541 tccacaagca caatccaaga tagttataca gtctttatcc tttatttctt ttaaaatact
    48601 atctatcaat tcaacaaaat ggtctatctg attgtatttt cttattttat cattttttat
    48661 cttaccatct tttgtaagta ctccaatttc ttttaaaagt gcatttgctt gtcctacttt
    48721 tacataataa tctctgtttt ttatttgaga tgccgtaaat tcatctattt taggtacttc
    48781 ttccttatta tctaaatatt ttacatttac cttcttattg tctccttcaa ttacaacaat
    48841 agttcctcgc tcaacatatt taaatactaa tccatcataa ttttctgcct ctttagaaat
    48901 attcttaagc aactcattaa acgtatataa atctgatttt cctttaaaat taaatttata
    48961 tttattatct tcctctattg caattccttt aaactctttt cttccagatt taaaaatcac
    49021 ctctaactca ataaaaaaat ccctattatc aaggtttctt tgagtaatcc ccataaaaaa
    49081 catatttagt tttcctatac tctgtttatt catcataatc tcccttttaa cttatatcct
    49141 taaatcttat taattaatat tatttgtttc tgaattattt atttcttctt ttaaatcgtt
    49201 caatctattt ttaaaacttt ctatctgctt atctgataaa tcaagatatt ctgttatctt
    49261 ccctatatat ttagggcttt tagtatttat taatttcaaa gcactttcca tagatttttc
    49321 tctaagctca tatgctttct ttacgtcatc tctagcatta ctcaatgttt ctgtatactt
    49381 ctccttagaa agttctggaa tctgcatatt ttcatattct tttacaactt ctttacactt
    49441 gtttctggca tttgtaacat ctttttttat actagataat ttagttatat tttttgctat
    49501 atccttagtg taaggtatgc attctctcat tggaactaaa gctgctcttt ctatattata
    49561 aatttctttc ttaaaaattc ctatactttc catatctatt ttttttatat cttcactatt
    49621 tttttcttta cttgtatatt tattattttc ttttgtatta tcttcttgtt tttctgattt
    49681 attattcact gaaacattac tatcagaatt attcttttct tttatatcat tacttccttc
    49741 ttcattactt tctttatttt gtatatttct atcttgtttg ttgtttaaat ttttattatt
    49801 tgatatttct tcattctttt tattatcctg gtttaaatca gtactttctt tttccttaaa
    49861 atttgataca tacttttcat catatgtctc atcagaaata taattgtgat aatacataga
    49921 ctcttttatt ttattaagtc cactcatata aatattactt atcattattg ttgtagctaa
    49981 taccacataa atactactgt agatacaaga cctcttaaaa ttcttgtaat ttctgaatat
    50041 cactactaaa ggaataagat ataaaaatat aaaaactaat atccacctca taagtcgtgt
    50101 ctcctttctc aaaaccgaaa tccctcaaat atttattttt aatcatgtat cttatagtat
    50161 ttaccaattt atgtttttta atcgtgaact tttattaaat taaattctgt atagtcacaa
    50221 gatgctaatg tatattctac tccatttcga atccccttca atcccatttt aaaagattct
    50281 ttaccatgca agtgaccata aatcaccttt tcaacattat attcttcaaa taactttgta
    50341 aataaagatt cttccaattt atcattcgta ggaggataat gagtaatcac aattattttt
    50401 gagtgaccac ttttacgagc agattctaat gatagtctaa gtctatgttc ttctctttta
    50461 taaacttttt catcagtctc atcaaattta acatcattag gacatatcca gcccctacct
    50521 ccacaaattg cataatcttt atattcataa aaatttgtct gaataaaacg catgtcttca
    50581 tatagcttat ttaaacttgt aacggttgtc caccagtaat catgatttcc ctttataagt
    50641 attttctgac ctggaagttt gcttattata tctaaatctt ttttagcttc ggataaatta
    50701 attccccaag atgtatctcc tagtactaag accatatctt cttccttaac aacttctttc
    50761 caattatcta taattttctt ttcatgacca tcccaattac ttccaaagat attcattggc
    50821 ttattgactg atgttgaaaa atgtaaatca cctatagcat acaaactcat aatatcattc
    50881 ctttcttaat tacactaaat aggctgtctc tttttagaaa ttattttcca ttaagaggca
    50941 gccccattaa tatttagcaa attttctaca agtagttttt actgaactac tttatcatct
    51001 accttagtat ccttatattg ctctaataat atatctattt cttgttttaa ttccaaaatt
    51061 tcagttatat ttttatctgt ttcagttcta tcaagttttc tttggtactg catagcttta
    51121 tgtgtatcac ccaagtcata taactcttgt attctattta gagtatctct aatagctata
    51181 gacttcattt ggtacatagc ctgagctttc attatgtcct ctcttatttc actcatttct
    51241 tggtctaaaa gaaaggcagc atcagatgct cttctaagcc tttcagcaag agtctcaggt
    51301 atgtaatggt catatttata ttttaatgaa tgttctattg tagcccagaa attcattgca
    51361 agagttctta tttgtatttc acatataatt tcctttgaac ccgcaatgga gtttataggg
    51421 tattttatta taacatgata gcttctataa ccactatctt tgtaatttgt aatataatct
    51481 ttttctccta ttatagtcat atcatttctt acttttatca aatcaactat agcatatata
    51541 tcctcaacaa actggcacat tattcttata ccagcaatat catcaatttc agtttctata
    51601 tcttttgcat ttatcctttt taacttagat attatggaag atattttttt tgttctacct
    51661 gtgacaaact ctatgggaga atattcacct tttgctaaat attcttttct tatattttta
    51721 aattttattt ttaattcctc tactgcatgt tcataaggtg ctagtatctc attccatttt
    51781 tcgtattcca tattgctcac cctttatttg ttttttatga ccttctttat tttatcataa
    51841 tttattttgt ttttgtatag taaagcaatt ctccattttc caatatatac cctatttctt
    51901 ctaaatcaac taagtaactt atgacagata ctaacgaaga tttaaaaaaa tgatactctt
    51961 tataattatt gcttaaatta ttgttattta taatgttttt taataaaatt tctaaagatt
    52021 tcggttctac aagcaactct cttatttgat ataaatattt ttttaaagca ttcaaatgtt
    52081 tttctattaa tttataagaa tcttctttcg atataacttg cttgccatgc cctaaaacta
    52141 agtactcaaa atctatattt tttaattttt ctaatgaatt tatttgttct tgtatatcat
    52201 atagaaacaa gaaatcgtat tttgataaaa tttcatctcc tatcaataaa tcgccaacaa
    52261 aaatcacatt atccttcgtc aaaacagcta tactaccagg tgtatgaccc tgaaattcaa
    52321 ttatatcaaa catttcattg tttaattcaa attttccagc ttctataaat ttatctattt
    52381 ttatatcatc caacatttta ttttttaaga tattatccat aaatacattg ctctttcccc
    52441 caacaatata ctttgaaaac aattctggat tttctatata taatttatcg tattcagatg
    52501 acattataca cacatcttta taatattctt taaattgatt acaagctcca tagtggtcat
    52561 catgaccatg agtatttata atatatctaa cctgtatatt attttcatct aatactttat
    52621 ttactctcct aggtcttgaa ccacataacc ctgggtctat cataagtgct gtgttatctt
    52681 caaatacata tattcctgta ttcgtgccac cttttataaa aaaggtattt ccttttactt
    52741 ttgtaagatt caccttcttc acctcatttt gacaatattt atgatacaat ttattactta
    52801 ctaatataaa actatacaag aacaatcctt tttattctat ctatagttct ttttcttatt
    52861 ttgtattctt tagatatcct tattttcaca ttatatgcta aatttctata aagtaatgac
    52921 tctataaaat attcaactat acctctatcc ctaaagtcta tatctatatt tccacttgaa
    52981 taaatatttg agtctaatat cataagctca tcaaaaaagc ttaatctctt agatttactt
    53041 aaataatctt tatttggaat aaatctatca caataatcta tcctgtaatt tactacttca
    53101 tcatttattt caaatccata ttgctttttc attaactctc tatagttatt atttttctca
    53161 ataacattat ctaaattttt attataatcc tcttttttcc aatgtccaaa catcctacaa
    53221 tttaatggtc taacttcata tattaaacat ctattattag tatctttaaa tggacatggg
    53281 ttctttcttg tatactcctc aaaataataa tctaatattt tacttataca gctttttttt
    53341 aaatcaactc tatcttcaag ataacaaaat atattcaaaa actcaattaa atttatacct
    53401 actgactcca tacaacaatt tccacatcca gaacaatttc ctactggcaa ggacttatat
    53461 acatcattta gtttgtcaaa gagcttattt ttaatggaat aatctataca atttaaaata
    53521 tctttatttt ttatactagt cattattatt actccttgtt ataattatta agttaataca
    53581 aacaattatt ataacatatt ttttaaattt aatcgcatat ggaggtattt tatgaataga
    53641 tatacaaaaa taattaatat gatgggaagt tattacacaa aagactttga aaaagaaaaa
    53701 aagaatgtaa taaaagttag agaagttaaa gaagatacag ttagaaaatt tttcttacaa
    53761 ggtgactgtg aagttcttgt agtatttgaa gacactggga aagaaatact tattgatgac
    53821 ttttctcctg aagaagatat caaaaaatat ttaggagcaa aatttataaa taaaaaaaga
    53881 tagttatcaa aaataattct aaaattaaaa tttaataaat gtacagttat aattctatat
    53941 aattatagtt aaaagttatc ttttattgct tttttagact ttaagatagc tttttttcta
    54001 ttttttgtaa aataattcca taattcacat taataattca caaaatgata taatataaca
    54061 aatagataaa tttttaaatt tctaaataca taattaatat tttgcgaggt gattttatgc
    54121 aaatttattt tagagttaag gctgttggca aacgcaaacc tatgctagaa cttacccctt
    54181 ttgatgtatc tgacaacatc aattgcctaa aagaagctat ctctgaaatt gtatctaaaa
    54241 atgttcttga atataatgag aaaatcccag aaaaatcaat aataaacttc ttaactaatg
    54301 aagaaattga atctcaagct gatattggaa aagttggatt tggctctatt tacaatgaga
    54361 ataaacaatc tgtagaaaag gcaatagagg tagcgttaca ggcatttgaa gatggaatct
    54421 acaaagtgct tataaatgaa gatgttattg aaaaactcga ttcctctata aatctgaaaa
    54481 gtggagatat atttactttt ataagactta ccttgcttgc tggaagaatg ttttaaaata
    54541 aataatttgg aggtacataa atgttagaac gtactagagt agaaaaaaat cctaaaataa
    54601 ttgaaaattt taaaaataat tttactaaat cttcttcaaa acagtactac gacttagcaa
    54661 agtctctttg ggactgcata gaaaatagtt catactatta tagagaacct gaagacaaat
    54721 tcttaaatat gataaagaaa tactacaatt gccactacta cgaaattaaa aatatggacg
    54781 agctcctttc tggaccttta aaaaatgcat tagaattaat atttacttct gaacaagtag
    54841 aagaactttg ccaattaatt aaaagaaaga tggattatac atattcagga ggatattatc
    54901 gtaaagggta tcgctcaaat aaacttgtgg attattttag aggtattata aggtttattt
    54961 caaactatgt tgatttaatt tattatgatt tttcagttat agattatctt actcttccaa
    55021 ataaggtctt gtactatgac tctataatga gtgataaaat agcactagaa atagacaaag
    55081 gaaatcaaaa agtaataagt gctttagaag aagtaatatt tggagaaaat caaactgctc
    55141 tacttacaag acaaatgata attggtatca tgaagagtca tagtgataaa tgctatgaaa
    55201 tgctttctaa acttcttttg gcagccaaac aacaagaagg acttagacag caaattgtag
    55261 agagtttaga tgagggtaca atttctgcat caatatacat gttaaaaact attttggaca
    55321 acaatttaga gcgatttagt tctgttataa gagccttgga tacatggaca ggacttggtt
    55381 tttcagacca aaaacctgga ataatacgta aatgtttaga actttcatat aaatcattga
    55441 ctgatgaaaa gttccgtata gaatcaatta atagcaatga taatcttgaa atttattttg
    55501 ccttatgggc tactgcaact tacaacatat atgactctta ctctcttatt gaaaacttac
    55561 tttcttgtca ggaaaaatat aaaaaacttg tagctcttta ctttttatcg catacagaaa
    55621 gtacatattt taaacattct atagcatcta aaaacattaa gggtgatgat ttagagatac
    55681 tagcatgggt aattacaaat ttctatgtag aaggttctgt tggctactac tatagttggc
    55741 aaaacagaga aactaatttt gacttgtcaa acactcctat tgacaaagac tttgatgcta
    55801 gaaaagaaca atttgaaagt ttaaaacata ctttagaaat tttaaattca aagacaaaat
    55861 cattttcagg aagtgtattt ccatggactt ggattgaaat ttcttctcat gaaatactta
    55921 aatgtatgat gactttaaca gcatacgata tgaatgctca atttatagat gtgcttatgg
    55981 aaaattgtca tcttatgagt tcagatttaa gagcttcact tatagtcaat tttgtaaatg
    56041 aaccaaagac agatagacaa cgtgaatttt tattggaatg tttaagtgat aagagtgttt
    56101 ccaatagaga aacggtattg agtctactta gaaagcttga gctaacagat gtagaattag
    56161 ataagataac caatctattg tctttaaaga caagctctat tagacaaaca gtaataaaaa
    56221 ttttacttga acaagatgat tcaaatttgg aaaatattgc ttcttcactg ataaaatctt
    56281 caaattctca aaaatgcctt ggaggtcttg aaattgtaaa cttattaaaa gacaatactg
    56341 ctagacaaga actatataat aagcttgttt tacttataga agatattgat aaatctaaaa
    56401 agaatacatc tcaagttcaa atactaattg ataatttgtt aggtaaagca aaaaatgatt
    56461 actgcaaaga aaatggtttt ggaatatata accctgaaaa caaagttcaa attccagaac
    56521 aatttgattt taaagatgat tctaatagct catcaaagct taataaaatt atctcaaata
    56581 taagtttatc tactcgtgag gattctgttt ctgtagcaac aaaaaaagaa gcaaaaaaaa
    56641 ttctcgatac ggatataaat aaaataataa aagtttatga aaaatttgat gagcttatta
    56701 ctgaaaatgc agattatgaa tatgaagttg aaagatggtc aggtaatgta gacaaagtac
    56761 ttttaggtta ttctacttat aacttgactc ctattaaata taaagtttct aatgatactc
    56821 ttgataatta tccattagca gagctttgga gagaaactag taaaaagctt gacttagatt
    56881 acaaattaat acttgatatt ttattttata gtataagtac atgtggatat aatgaaacag
    56941 aaaaaagttg gttttcatct atatattcaa atgtccttga ctctaaaaaa caaaataaaa
    57001 tatatacaaa acttgaaaaa cttaaattta atggacttac aagaaaactt ttaagagttt
    57061 tactaaatga gtttgaccat aaagaaatat ttaactattg tttagaaata tactataaac
    57121 ttagaaactt attgactata gaacaatgta aaaaacaaag agttgaattt actaaaaact
    57181 attacagaca aaatgaatac tgccctgctt taaatgcccc tattttaaac tattggcttg
    57241 ataaagcaca ttcgtttatt tatgatgata tttcttttac taagtttttc tacactacgt
    57301 tttcaaatta tcagttgcta gaatataagt ttcctttcta tactagcata aatgtgtttg
    57361 ctcgtgcaca tgaattagga ttaatgactg aagagcaagt taatagagaa atgataagtg
    57421 gatacaacgc atcaaatata ataagaacat tgacaaatcc tagatgggct ggcgacacat
    57481 tagaaaagta cccttggctt aaagataatt taaaaactgt tacaaaccga attatagaaa
    57541 ttgaatcacg tagaggtgat atgccaacag aggtgtctca tctagctaat aatatacaat
    57601 actttgaagg tataaattat tttgtaaata ttttggtcgc tcttggtaaa gaaacgttcc
    57661 agagaggata ttcatatggt agcaattatt caaaaaaaga tgttttaagt tctctactta
    57721 aaaattgcta tcctactaaa gaagatgact caaaaaaatt aaaaagttta cttaaaaata
    57781 ccgacattac tgagttaaga ttgatagaat ctgctatgta tgcccctcaa tgggtaaaca
    57841 taattgaaaa atatttaaac tggaagggtc tgaaaagtac aatttggtac ttccatgcac
    57901 atataaatga aggcttctct gcacaaaaag aatcagaggt tgctctattc tcccctattt
    57961 caccacgtag tttcattgat ggtgcatttg atgtagattg gtttttagat tcatataaaa
    58021 ctattgggga agaaagattc aatatacttt acaagtcagc taaatatata actagtggtg
    58081 gtaactctca tagacgtgca caactctatg ctgatgctac acttggtaag cttgataaag
    58141 acatgttgat gaaagaaatt gaaacaaata gaaatcaaga taaattgaga agtttctctt
    58201 tacttcctat gaaaaaagga gacctaaaag aagcaacttt ccgttatgaa tttattcaaa
    58261 agtttgctaa agaaagcaag caatttggtg cacaacgtcg tgaaagtgaa tcaaaagctt
    58321 gtactatagc gctagaaaat ctagctagaa gtgctggatt tggagatgta aatcgtatga
    58381 tgtgggctct tgagactgaa aaactaaatg aagttgctca tctatttaaa ccaaaagata
    58441 ttgatggtac ttcaatttgg atagatgttg atgaaaacgg aaaagcatct actaaagttc
    58501 aaaaaggcaa caagtcttta aagagtatac caaaagctat tgctaaacat ccatatgtac
    58561 ttgaacttaa atctgtccaa aaagatttaa agagtcagta ttctcgtgca aaacagagtt
    58621 tagaacaagc tatgaaaaat gaaatagtat ttacagttaa agaaattgcc aatatctata
    58681 aaaatccagt tatctgccct ttgattaaaa atctagtatg ggtatgtgat gataatattg
    58741 gatatgttta taatgataag tctaagttct ttatttgcaa tatagaaggt gaaacttata
    58801 agttgacggc aaaaaataaa ttaaaacttg cacatccagt tcatttgttt gaatctggta
    58861 agtggagtga gttccaacat gatttattta gtaagcaaat tgttcaacca tttaagcaag
    58921 tattccgtga gtattataga ataaacagtg atgaattatc tgaaaaaact atatctcgca
    58981 gatatgctgg tcaccaaatt cagccaaaga aaactgtagc acttcttaga aatcagcttt
    59041 ggactgtcga ttatgaagag ggattacaga aagtatttta taaagaaaat atagtggcaa
    59101 agatgtttgc acttgcagat tggttttcac cagcagatat agagcctcct actattgaaa
    59161 cagtagaatt ttttgataga aaaacttata aaagtttaga attagcttct atacctccaa
    59221 ttctattctc agaagttatg cgtgatatag accttgttgt aagtgtcgct catgctggtg
    59281 gtgttgaccc tgaaactagc cattctactg tagagatgcg tatagcaatt gctaaagaac
    59341 ttttattatt attaaaaatt aacaatgtca attttgaagg ctctcatgct cttatagcag
    59401 gtaatttagg tgagtattct gtgcatatgg gttctggtat tgtacataaa aaagggatgg
    59461 gtgctttgaa tatacttcct atacattctc aaagtagagg taagatattc cttccattcg
    59521 ctgatgaaga ccctaaaact gctgagatta tgtctaagat actattactt gctgaagata
    59581 gtaagattaa agaccctagt atcttaagta atttataagt ataaaaacta tccctaaaat
    59641 atattggact ttcttaaaaa aaattagaaa gtccaatata tactatactg taatttatat
    59701 agattaaatc ataattacaa ataattttta tataaacttc tcttatacat tatctttatg
    59761 gtacttatta tatcacacaa aaagtatttt tcttctatct tcactagaat cttttaaccc
    59821 tataaaatct atataaaaaa tctttttcta gagatttgtt taatatggca ttttcttgaa
    59881 aatttataaa ccttatctct aatgaagatt tatttatagg tataacctta tgtataaatc
    59941 ttagatttac tatgtattgt ctatgggtca taaagaaatt aggaggtagg cgttttttta
    60001 aatcatcaaa gttctcataa aactttatta tatcttcatc tttagtgtgt agattaattg
    60061 ctcttgaatt tttctcaaac ataactatat catcaaaatt aatcatatgt atctgcttcc
    60121 ttattttata tacaaaaagg gtgtcttcta taaaattatt attagcaatc ttatgggagt
    60181 taatatggtc tattgctatg ttaattgaat caagtatttt ttctttttta aatggtttaa
    60241 ctacaaaatc tataggatgc actttaaagc tttcaagact ataatcagcg aaacccgtca
    60301 caaatactat atgtatatcc ttatctatag aaagaatttc ttcagcagaa tcaatcccat
    60361 ttttatatgg catatcaatg tcaataatca ataaatctat tttctcattt tttataaatt
    60421 caattgcctc tataccatcc ttaacttttt taacataatc tacatatcca gactctttag
    60481 ctatatttgc tatatcatct cttacaatct tatcatcatc acaaatcaaa acttttatca
    60541 tagacttttc tcctcctaac taataatatt ttgggattaa gattacaaat tcagttaaaa
    60601 aatcatcact atttacaagt atactataat catacttatc taatatattt ttaactaaat
    60661 gtagcccata tcccctatct tgtccttctt tagtactaaa tccattccaa aatatacttt
    60721 caacattatg tattttagga ccattatttt ttatagctat aatatactga aattcatctt
    60781 catatgcatg tactcttata tacttctttt ctttttttat agtagacaaa gactctattg
    60841 cattatctat tatgtttaat agtactgaac tcatatcatt aggttcaatc tctaaattat
    60901 ccataaaatc ttgaatgtag acatcaaaag atatatcctt ttcaagacat tcctcgtatt
    60961 ttaatgaagc tatagcatct aaataagata cttttccata ccttgaattt tttgatttaa
    61021 aactatttga tatattcatt atatattctt tggcatcttc atctagccca gtatttaata
    61081 gagaatacac cacttgcaaa tgtttcaaat agtcatgttt ttgacttctt aatttgataa
    61141 ttatattatc cttatgattt attttactat ctagtttttg tagtttatat tcctgttcat
    61201 tattattatt tatcaatctt ataactttaa agcctgtata aaaacttaaa ataattaaaa
    61261 ccaaaaaaag tataatattt aatactcctt caagtaaaaa actatatcct aacc
//
LOCUS       DAEPHU010000016        59184 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 01A10CD0081
            SAMN05941466-rid12468953.denovo.016, whole genome shotgun sequence.
ACCESSION   DAEPHU010000016 DAEPHU010000000
VERSION     DAEPHU010000016.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941466
            Sequence Read Archive: SRR6291087
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 59184)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 59184)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068158.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 22:43:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,892
            CDSs (total)                      :: 3,805
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 87
            rRNAs                             :: 8, 1, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 55
            CDSs (without protein)            :: 55
            Pseudo Genes (ambiguous residues) :: 0 of 55
            Pseudo Genes (frameshifted)       :: 21 of 55
            Pseudo Genes (incomplete)         :: 28 of 55
            Pseudo Genes (internal stop)      :: 16 of 55
            Pseudo Genes (multiple problems)  :: 8 of 55
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..59184
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941466-rid12468953.denovo.016"
                     /strain="01A10CD0081"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            242..424
                     /locus_tag="KR231_001067"
     CDS             242..424
                     /locus_tag="KR231_001067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0003472.1"
                     /translation="MKKFRKHKSISNCISILLILYLTLGSLLPNNIYAQDLQSYSGKV
                     CNTTYKAPIERSEGFF"
     gene            642..785
                     /locus_tag="KR231_001068"
     CDS             642..785
                     /locus_tag="KR231_001068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0003473.1"
                     /translation="MYVYYFESPEKFAFNKVIRTKNQNEISLEKFNEFKETIQDKLLP
                     YNR"
     gene            760..2327
                     /locus_tag="KR231_001069"
                     /pseudo
     CDS             760..2327
                     /locus_tag="KR231_001069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_021426623.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="iota toxin protein Ib"
     gene            complement(2979..3980)
                     /gene="trpS"
                     /locus_tag="KR231_001070"
     CDS             complement(2979..3980)
                     /gene="trpS"
                     /locus_tag="KR231_001070"
                     /EC_number="6.1.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan--tRNA ligase"
                     /protein_id="HBH0003474.1"
                     /translation="MSEKKVILSGAQPSGKMTLGNYLGAIKNWTELQDNYDCYYSIVD
                     LHAITVPQDPKVLRANTIELLAQYIACGLDPEKNTIFIQSHVKEHVELMWVLNTMTYM
                     GELSRMTQFKDKSQKSEANLNAGLFTYPVLMAADILLYQTDLVPVGDDQKQHLELARD
                     LANRFNNRFSPTFVVPEGYYPKGGARVMSLQEPTKKMSKSDSNENAFILLADDSDSIK
                     RKIKRSVTDSLGVVKYNDEQPGIKNLIDIYSNLSKKSVEEIVNMYEGKGYGIFKEDVA
                     EVVSEALRPIREKYVDLLNNKDYLEKIYSMGAEKAEKQARKTLRKVYKKVGFIERRY"
     gene            complement(4003..4701)
                     /locus_tag="KR231_001071"
     CDS             complement(4003..4701)
                     /locus_tag="KR231_001071"
                     /EC_number="3.2.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5'-methylthioadenosine/adenosylhomocysteine
                     nucleosidase"
                     /protein_id="HBH0003475.1"
                     /translation="MNVIGIIGAMDEEVSILVDLMDIRETIKKASLEFYKGILEGKNV
                     VLVKCGIGKVNSALCAQILISEFKVDAIVNTGVAGALNEKLDVNDIVISTDAIQYDVD
                     TTAFGDPKGVIPRMKTSVFKADERLIDAAYKSSVEEVKTHKVLKGRVVTGDKFINSKE
                     LKEELVNDFGGYCGEMEGGAIAHVCYLNNTPFVIIRAMSDKADGSADVTYDVFVHDAA
                     NNSKDIVLNMLKSI"
     misc_binding    complement(4744..4984)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(5075..6478)
                     /locus_tag="KR231_001072"
     CDS             complement(5075..6478)
                     /locus_tag="KR231_001072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HBH0003476.1"
                     /translation="MEKKKIGLWSLVFMNVSALYGIRWIAKSTASSFGLGLGAIPMWL
                     LFSFIYFVPGALICAELASTYQKGDGGLYDWVKEAFGEKYGFLVSWLNWTAKIFWYSS
                     FLTFLAVNVSYTIGNPALADNKMFVLILSLIIFWALSLIATKGISFTKIFTNTGALGS
                     TIPSAILIIFSFVAVFVLKKHDIASTYTIASMTPKLNMDAFVAISAIMFGLAGAETAA
                     NFITEIDKPEKNFPKAILISAGIVASLYVLGSIAITMIIPPDQITASKGVLDALSAVC
                     ASLGIGSWLVQLIAFGIAFSVLGAIVLYIASPIKMLFGSVKKGIFPDSLVEVNEHKIP
                     SKAVILQAIIVTIILLVTTLMPSVDAIYNVLVTMTALTALFPYVLLYASYIKLRKERP
                     DEIRPYTMAKSTSTCLGLAKMVLVVTVVGILLSAAPVMPTFAENVIYEIEMIGGGLLV
                     ILSGLWLWNRYEKKTAK"
     gene            6975..8051
                     /locus_tag="KR231_001073"
     CDS             6975..8051
                     /locus_tag="KR231_001073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HBH0003477.1"
                     /translation="MKAQRLNAVLEQMKKDDISQMLVSDPTSIFYLTGVLIHPGERLL
                     ALYLNLNGNNKLFINELFPVSEDLGVEMVWFNDTQNPVEIITEHIDKNATMGVDKNWP
                     ARFLLNLIELGGGSKFVNSSYIIDTLRMCKDEEEKELMRIASKLNDKAMEQLKATVSG
                     ELTEKQLVGKLSKIYEDLGTDGFSFDPIIGFGPNGANPHGEPGNALVKPGDAIILDIG
                     CIKDNYCADMTRTVFYKEIPEKGREIFEIVLEANKRAEAIVKPGVRFCDIDAAARDYI
                     TEKGYGQYFTHRTGHSIGLEVHDKGDVSSINTDTVQPGMIFSIEPGIYLPGEFGVRIE
                     DLVLVTEDGCEILNKHDKEICVVG"
     gene            complement(8168..9010)
                     /locus_tag="KR231_001074"
     CDS             complement(8168..9010)
                     /locus_tag="KR231_001074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HBH0003478.1"
                     /translation="MDKIKLIVDSACDLPDDIIEKYNIEVVGLNVSFGEESYISGKEI
                     DNETFYRKMSESKVLPKTSCPSPDKFLEAYHCQEESVLVINISSGLSGTYNSALLAKD
                     MFEKEGNNKKVEVIDSLSGSIGIGQLVLKAAILIKEGKEIEEIVSIINKYKDNPPFFG
                     TLETLENAIKGGRINPIAGKIINTLNFKAIIQVADGVVTPIDKARGEGNSLKKLITLV
                     ESKIKDKEEKVLFIGHANCPEKAQKVREVMEKDVKYKDVVICEVGSVMGTYTSKGAIL
                     ITAI"
     gene            9194..9766
                     /locus_tag="KR231_001075"
     CDS             9194..9766
                     /locus_tag="KR231_001075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBH0003479.1"
                     /translation="MKTNNMKQAILSSATNLIAKNGVQNTSLADIAKDVNISKGTLYY
                     HYASKDDIIYDIADTHLEVITSAILNCVKNVKSKNSQIEMVNLILEKISTIESRGRVH
                     MYLICEAITSNNDLKERIRLKYIEWRTTLKSEIVESLEKYNSSENEQDAESFSFLLMS
                     IVDGLVVQSLLKTEKIPYENIASFLVNHWI"
     gene            complement(9929..10201)
                     /locus_tag="KR231_001076"
     CDS             complement(9929..10201)
                     /locus_tag="KR231_001076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0003480.1"
                     /translation="MLRERFVVRNHHNPHTSGCCGTGGEGCCGGDNHEHSHQHSHSHG
                     HEHEHVNGVGHDHNHDDGFSGTHEHSHEHTHTHGHEHSDGHTHEHK"
     gene            complement(10328..11200)
                     /locus_tag="KR231_001077"
     CDS             complement(10328..11200)
                     /locus_tag="KR231_001077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HBH0003481.1"
                     /translation="MYGESKKLSIDNNIFLQYCLIILGMILSTLGINLYLAPAKLLSG
                     GVAGICVILYKLFGINQGISSFLMNIPIFIIARKYFDNKFLLISFVNMLLFSLALGLT
                     QDIAKYFPIDDTMLQCIYGGALTGIGMGLTFKARATAGGLDIIAAIMKRKYDIPMKNT
                     FLFINFFVVCAGAFLFGAKLVMYTLITMYIISFTMDIGKDCFDRKKSILLISNKYDEI
                     SKVIMNKMGRGVTFLEAEGAYTQNKKKMIYCIISANEIGKFKDLIYDMDSEAFISVNN
                     VEEVKGGGFKDKFL"
     gene            complement(11487..14594)
                     /locus_tag="KR231_001078"
     CDS             complement(11487..14594)
                     /locus_tag="KR231_001078"
                     /EC_number="6.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728473.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoleucine--tRNA ligase"
                     /protein_id="HBH0003482.1"
                     /translation="MAKFKPLVDSSVKQAEAQVFDYWKDINILEKTLEKGKDDPSFVF
                     YEGPPTANGNPGVHHVLSRTLKDSVCRYKTMSGYQVKRKAGWDTHGLPVEIQVEKELG
                     LTSKQQIEEYGIAEFNQKCRESVFSFEKQWRIMTERMAYEVDLDNPYITLDNNYIESV
                     WWILNKFNKEGYIYEGHKILPYCPRCGTGLASHEVAQGYKEVKTNTVIAKFKKKDADE
                     YFLAWTTTPWTLPSNVSLTVNADVDYLKVKKGDEVYYVSKPLADKVLGEDYEVLEEMK
                     GKDLEGLEYEQLMPFVEVDKKAFFITVGDYVTTEDGTGIVHTAPAFGEDDYNTGKRYD
                     LPVIQPVDETGKFTSTPWEGRFVMEDGLDVEIIKWLASENKLYSKEKVVHNYPHCWRC
                     QTPLVYYAKPSWYIEMTKLKDKLIENNNGVKWFPSFVGEKRFGNWLENLNDWAISRTR
                     YWGTPLPIWRCECGHTDSVGSRAELAEKAIEDVNPETVELHRPYVDDIHLKCEKCGKP
                     MTRVTEVIDCWFDSGAMPFAQHHYPFENKENFDQLFPADYISEGIDQTRGWFYSLLAV
                     STFVLGKAPYKSVLVPDLVLDKDGKKMSKSRGNTVNPMELFDQYGADALRWYLLYVSP
                     PWTPTKFDMDGLKEIQSKFIGTMKNVYNFFTLYANTDDINPTEFFVEYKDRPELDRWI
                     LSKFNNLMKDVEENLAIFELNKTLRMIQDFINDDLSNWYIRRSRRRFWATELTEDKKA
                     VYNTTYELLHGLCRAIAPFAPYMSEEMYRNLTGEVSVHLAEYPKCNEELVDTKLEEKM
                     DLAKNLVTLGRASREVERIKVRQPLQKVLVDGKFEDTISDVVDLIKEELNVKEVIFAK
                     DLDEYMNFSLKPNFKEAGPLLGSKMNLFVGALSKLNAHETANKLEKGETLTVDLDGEA
                     FEFNKDLVLIGITAKEGFNVSVENNLFVILDTKLTEELINEGYAREFISKVQQLRKSN
                     NFEVLDNIVIEYCGDDEIAKAVDHFNEYIKSETLALEINRVDDKSLEEQNLNDHMTGI
                     KVIKK"
     misc_binding    complement(14687..14919)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(15094..15621)
                     /locus_tag="KR231_001079"
     CDS             complement(15094..15621)
                     /locus_tag="KR231_001079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DivIVA domain-containing protein"
                     /protein_id="HBH0003483.1"
                     /translation="MLTPIEIENKEFKKGLRGYRDEEVDEFLDIIKEDYESLCRENTA
                     LKEKLGLYQDQVNKYENIEETLKATLITAQSAAEDTCSAANKKAKIIVEEADLKARQI
                     IEQANNRVIEIRKEYDALVKEFKIFRNKFKSLLEDEIRSVDEIFYDVDEKCVNAFEGT
                     TVYNYSNDEAATTLE"
     gene            complement(15656..16441)
                     /locus_tag="KR231_001080"
     CDS             complement(15656..16441)
                     /locus_tag="KR231_001080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding protein"
                     /protein_id="HBH0003484.1"
                     /translation="MDKLKLTNHIKDIDLKNKMFKVIDKANSCIKNYDVKSTEFLNPY
                     EVKNAVAILNSTNEIKYSVDGGYEQAERSTVFIYPFYMEYEDIEDTLRFLQIEGNFKF
                     KNISHKDYLGSILGLGIKREKIGDIIIHDSFCQVVVSSDICDFIIVNLEKVSRNNVIV
                     KEISRENIVNSSSKYKEVSFTVSSDRLDCVISGIYNISRQDSAKYINGEKVHVNYEKI
                     TSTSKIVKNDDLISIRGKGRAKVTQIGDITKKGKIKVQARLIV"
     gene            complement(16451..16708)
                     /locus_tag="KR231_001081"
     CDS             complement(16451..16708)
                     /locus_tag="KR231_001081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggT family protein"
                     /protein_id="HBH0003485.1"
                     /translation="MGTIRIALYYLLDIIAWMIVIKSLMTWFPNGRQSKIFDILENLT
                     EPIEGPIRSIMYKYTNGPIDFSPLIAIVLLMFLRQLVLVIF"
     gene            complement(16727..17185)
                     /locus_tag="KR231_001082"
     CDS             complement(16727..17185)
                     /locus_tag="KR231_001082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein SepF"
                     /protein_id="HBH0003486.1"
                     /translation="MSNGIISKFKNWIVDEEEDYIEDEYESGMDDIVQEEEMNSGFST
                     AKANKIVNLHTTSQMKVVIVEPKVYDEAATIADHLKQRRAVIVNLEGLTNSEVRKSIF
                     NFMNGAVYVLDGSIQKVSKSIFILAPNNVDIDANMKKELESKAFFPWQNK"
     gene            complement(17225..17929)
                     /locus_tag="KR231_001083"
     CDS             complement(17225..17929)
                     /locus_tag="KR231_001083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggS family pyridoxal phosphate-dependent
                     enzyme"
                     /protein_id="HBH0003487.1"
                     /translation="MGSIKDNLSEIRNKIDKAAKKVDRDSKEITLLAVTKTVDVDLVN
                     EAMREGITSVGENKPQELARKYDIIGDKLNWHLIGTLQTNKVKYIIDKVCMIHSLDRI
                     ALCEEIQKRAEQINREIDCLVQVNISKEESKHGLDREEVVDFVKEVSEKYKNIKIKGL
                     MTMAPFIEDEDEIRGVFKGLKDLSKQIKELNIPNVGMDVLSMGMSHDYEIAIEEGATI
                     VRVGTSIFGERNYNKK"
     gene            complement(17939..18574)
                     /locus_tag="KR231_001084"
     CDS             complement(17939..18574)
                     /locus_tag="KR231_001084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0003488.1"
                     /translation="MKKVKYTRLVILGILIYLVFNILVMIISKNVDTLVLKNEKVDAK
                     IHVKGTIEKDANDQSNYLSTYISKEDSNNFEKNQNVIIEYHEQKLDAKVYKIYENNNK
                     IMVKLKISNQIVANQDTSVEEFDIIYNQMECLKIPKTSIKTKDNKRGVYVIDEQSQSV
                     KFVILEGITYENESSVFVDYYKNDINGVTSVNLYDKIILRPNSINTNIRIK"
     gene            18955..19995
                     /locus_tag="KR231_001085"
     CDS             18955..19995
                     /locus_tag="KR231_001085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBH0003489.1"
                     /translation="MSEILLGTGLLLLVLCCFTIFSYKAPYGMKAMGALANAACATFL
                     VEAFNLSLLGDVLGMEFFRSVGAANGSLGGVAAAILVPLALGVSPVYAVLIGLSCLDF
                     SILSGFVAGYFVSFLIKFIEKKVPPGVDLVVVILLCAPLSRLIASNVDPLVNSTLLQI
                     GQVLIEATNISPIIMGIILGGLITVVGTSPLSSMALTSIIGLTGLPMAIGALGAFGSA
                     FMNSTLFAKLKLGSKKDIISVAIEPLTQSDIISANPIPIYSTNFFGGAFSGIIVALMG
                     LVNMTPGTATPVAGFAIMFAYNPVQQVLITAGLCALFNVIAGFLGSKIFSTFKVLTAG
                     EIRGTDVEEEIA"
     gene            complement(20458..21813)
                     /locus_tag="KR231_001086"
     CDS             complement(20458..21813)
                     /locus_tag="KR231_001086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009170073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PFL family protein"
                     /protein_id="HBH0003490.1"
                     /translation="MNVGNILETIKMIDEEQLDIRTITMGISLLDCIDPDGDKAREKI
                     YNKIMSSAKDLVKVGKDIEREFGIPIVNKRVSVTPISIIAGATDENDYVKFAQTLDKA
                     AEDLGIDFIGGFSALVQKGYTKGDKILIKSIPKALASTNKVCASVNVGSTRCGINMDA
                     VKEMGEIIKETAELTKDAKGFGCAKLVVFCNAVEDNPFMAGAFHGVGEADRIINVGVS
                     GPGVVKRALEKVKGEPFDVVSETVKKTAFKITRVGQLVAKEASSRLDVPFGIIDLSLA
                     PTPAIGDSVANILEEMGLEVVGTHGTTAALALLNDAVKKGGVMACSHVGGLSGAFIPV
                     SEDAGMIDAVIKGALSIDKLEAMTAICSVGLDMIAVPGNTTAGTLGAMIADEAAIGMI
                     NNKTTAVRIIPAPGCDVGDMVEFGGLLGRAPVMPINTNSSELFTQRGGRIPAPIHSFK
                     N"
     gene            complement(21839..22108)
                     /locus_tag="KR231_001087"
     CDS             complement(21839..22108)
                     /locus_tag="KR231_001087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010963800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACT domain-containing protein"
                     /protein_id="HBH0003491.1"
                     /translation="MKAILTVIGKDKPGIVAGISDELYKQNINIVDISQKILQDYFTM
                     IMIVDLEKSLNSFEKTVEDLVERGKKLSVDVKIQREEIFNSMHNL"
     gene            complement(22398..24353)
                     /locus_tag="KR231_001088"
     CDS             complement(22398..24353)
                     /locus_tag="KR231_001088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0003492.1"
                     /translation="MKKYEIFIFMSIIVLCFISFPHKVFGQEENCLEDFERWVQENKN
                     NKEEIVYTLSCDMVIDEEFRFYIPYDSNFTIDTNKYKILIKNHGRFIIDDNELNIIGE
                     GGKEGVIHIENGGSISIGINNIIATDGTALYVEEGGDLHIKSSYESVEKIKANGKDAI
                     GIYTENDIRILNKDIEVNGEHAIGVYSKGDVEIEETSIKAYSSNNESGLLRDNNKLAQ
                     SIISESKKVYIIDDYNELIPSIAEDSGYDIVKCCHRGIGVFSDEIKVSKDDKIENIKF
                     PKYMVLETSSGNRLDIDVEWDFTDYYEKLEKGENFNITGKFKTEMLNKEKIIINDDVV
                     PILNVSVIEKKPIDNLELEFQNTKNGYVAVLFYDMPYSASKVFVEYSSDGINWISEEQ
                     EDIRDQAILFFEDFKLRCFRVKVVGGLKEGYSNIVFKPGFIMGGGDNQETPDDEREND
                     DIDGDRGGGGRDDPDRDEDDNNQDGNNGNENNDSNNNQNNNNENNNNENDNSDEKQPN
                     TPKDDVESSTDSNENKNPHDIPKDGNKENNSDKEKGFYNKNSITENDDNYDLSSKSVF
                     GTNEHSFPYRESISNKNQDTNKNKSNISDYDGIINNNYKLESKEYNLKKDIIFLFCIL
                     TPIMIGSILIVNPDTRKSIIKFIKLKK"
     gene            complement(24536..26011)
                     /gene="spoIVA"
                     /locus_tag="KR231_001089"
     CDS             complement(24536..26011)
                     /gene="spoIVA"
                     /locus_tag="KR231_001089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage IV sporulation protein A"
                     /protein_id="HBH0003493.1"
                     /translation="MNNNIYEDISKRTQGDIYIGVVGPVRTGKSTFIRKFMEKLVIPN
                     IDNEFKKDRTRDEIPQSGSGKTIMTVEPKFVPADGVEIKIKDTVSLKVRMVDCVGYIV
                     EGALGHEEGGKQRLVSTPWSQEAMTFEKAAEIGTKKVIKDHSTIGIVVLTDGSVTGID
                     RKSYVEPEERVIQELKNLKKPFAVVLNTLSPKSEETSMLRSELEEKYEVPVLPMNVVE
                     MEEEDIEEVMEAVLYDFPLTEIRINLPKWVEGLERNHWIKSSIITTLKQSIIDIGKIR
                     DIEGIIQGFSELEFLEDTGVDNVELGEGVINIDLQTKQDLFYNVLEEKSGFKIEGDYQ
                     LLSLITRLSKVKNEYDKIESALIDAKIKGYGVVAPSLEELSLEEPEIMKQGKQYGIKL
                     KANAPSLHIIKADISTEVSPIVGNQNQGEEMIKYLMEVFEEQPADLWESNMFGKSLHD
                     LVKEQLQSKLYTMPEEIRVKMQKTLQKIVNEGSSNIITILL"
     gene            complement(26183..27478)
                     /locus_tag="KR231_001090"
     CDS             complement(26183..27478)
                     /locus_tag="KR231_001090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBH0003494.1"
                     /translation="MSVEVNKPSIWKNFKVLIILFVAGAFIYALPYLKNYYYDTFAQA
                     FNLTNTQMGSLGSIYGLLAMVSYLFGGFLADRISARKLLSGSLIITGISGLVLTLYPP
                     YIVVFLIHALWGITTILTFWPALVKAVRMLASENEQGKAFGFMESGRGITNAIHLSLV
                     LILFGYISSKVSDKSGLTAIIVLYSAINVIVGVLVFFKLKDNEKEVSAKFDKEAFFAV
                     IKMPHTWIITIIMFCSYSANMSFYYFTPYSTEAFGATVVFASAISILAQYCRPVASAA
                     SGLLGDKVGSSKIISYGFILMIAGLLGVIFTPTKSSMIYILLIGCVAIYVSMYAIQGL
                     HYSLLEEGNYSLSISGTAIGIVATLGYLPEVLCPLAAGKILDAFPGVTGYRYYFIVLT
                     IVAIIGLVFTFIWMNMTKERRKELIEMNNNSNENTTKVS"
     gene            complement(27662..29071)
                     /locus_tag="KR231_001091"
     CDS             complement(27662..29071)
                     /locus_tag="KR231_001091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HBH0003495.1"
                     /translation="MKKKIGFWDLVFMNISALFGIRWIAKSTASSFGLGLGSIPVWLL
                     FAFIFFVPASLICAELAATYPKDGGLGEWVKQAYGEKWGFMVSWLNWTSKIFWYSSFL
                     TFLAINIAYMLGNPDLSNNKMFILALSLIIFWLLSLVSTRGMAFGKFFTNTGALGSTI
                     PAILLIVMAFMSVVILKKAPSASIYTIQNIIPKIDANSLVSISAIIFALSGAETTANF
                     ITEMDNAKKNFPKAILTVAVLIGGIYILGSVAITMILPPDKIAASTGILDALAKVAQD
                     LGIGSWFIRIVAFGITLSVLGALILYIAGPVKMLFGNVREGVFPKQLTVTNKYNIPSN
                     AVIVQAIIVSLLLVGTNLLPSVDNIYNVLVTMTALTALFPYVLLFTSYIRLRKTRPNE
                     ERPYSIAKSDSVCINIARMVLVVTVVGILFSTAPVMETLKDNIIYEIEMIGGGLFVII
                     TGLMLWKNYEKKISNNSGR"
     gene            complement(29123..30262)
                     /locus_tag="KR231_001092"
     CDS             complement(29123..30262)
                     /locus_tag="KR231_001092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HBH0003496.1"
                     /translation="MSNNMRLERLRKYMNEKSIEIALIFEPDNQFYISGFKAITYSRP
                     IVTVVTQDKIELIVPGLEELHAKEVAKVDNVYVYYEIPEMKEHGISHKHYLDIILNKY
                     PKGTTVGIEKDIVSASFSEYITDKSFAIKDVGSKIFEMRYVKDAKEIEFLKIAGYLSD
                     IGIKGSLENVRVGMSELEFDVEGDNALLKYVSENYPDTYIGFANWTCSGIDRTAQPHL
                     DSNTRILQRGDIVIHSRQVWYENYRAENERTFIIGKPTERQKEVFKIAVEAQQAGLDT
                     IKAGIPARMVDEAARAVVAKYGLELYSNHRIGHGLGLSEHEEPYLRFDNELILEEGMV
                     FSMEPGIYIPGVGGFRHSDTAIVGKNGATIITNYPRSVEELILDI"
     gene            30581..31231
                     /locus_tag="KR231_001093"
     CDS             30581..31231
                     /locus_tag="KR231_001093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBH0003497.1"
                     /translation="MTNKELQKKRILMYFIEAAQNIMENEGIENITLRKVADMAGYNS
                     STLYKYFKNLDHLISFASIKYFKDYNLNISRCIENVNDEYKKYIIMWKLFCKHSFDNA
                     QAFYQVFFNLSSDELSYITKQYYDMFPEDLGIHDSDISLMITGESIKERNKILLNNLV
                     DTGYIPAKDLDIINDIIISFYQNLLFLKKNTGKNSDDDELTMKMISSIEYIIKHAK"
     gene            complement(31388..32407)
                     /locus_tag="KR231_001094"
     CDS             complement(31388..32407)
                     /locus_tag="KR231_001094"
                     /EC_number="1.1.1.94"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent glycerol-3-phosphate
                     dehydrogenase"
                     /protein_id="HBH0003498.1"
                     /translation="MEKVCVLGTGSWGSALALGLAKKGNDVSMWTRKEEQAKKINRTK
                     ENTDYLPGVLFPNNITISTDIEKTIKDCKVIVLAVPSQAVRSTCQKIKPFIKEGQVIV
                     NVAKGLEKGTGLRLSQVCEEELPQNPYVILSGPSHAEEVARDIPTTVVVASKDLKIAQ
                     MIQDLFMSPKLRVYTNPDIVGVELGGALKNIIAFGAGICDGLGYGDNAKAALMTRGIS
                     EMSRLGIAMGANMSTFAGLSGIGDLIVTCTSMHSRNRRAGILIGKGMSLEDTLKEVKM
                     VVEGITATEVAHDVAEKLDIDMPITNAIYSVIKKGSNPKEVGIELMMRSKKHEMEEVV
                     LGDDI"
     gene            complement(32438..33052)
                     /gene="plsY"
                     /locus_tag="KR231_001095"
     CDS             complement(32438..33052)
                     /gene="plsY"
                     /locus_tag="KR231_001095"
                     /EC_number="2.3.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol-3-phosphate 1-O-acyltransferase PlsY"
                     /protein_id="HBH0003499.1"
                     /translation="MEIFSYIIIAVVAYLLGNISTSYIVAKRIAGVDIRTQGSGNAGS
                     TNVLRTLGKRAGAMTFLGDVLKGVMAVLISEFAARLVGIDTLLAGYLAVICVVAGHNW
                     PAVLGFRGGKGVATSLGAMLAVNPVITLMCLAVFILVVAITKYVSLGSVVGIGCSPIF
                     MIMVKNKAGLIVALFLTASVIYNHRANIKRLLNGTERKIGQKKE"
     gene            complement(33087..34406)
                     /gene="der"
                     /locus_tag="KR231_001096"
     CDS             complement(33087..34406)
                     /gene="der"
                     /locus_tag="KR231_001096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012063975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase Der"
                     /protein_id="HBH0003500.1"
                     /translation="MSRPVVAVVGRPNVGKSTIFNKFAGKRISIVENTPGVTRDRIFA
                     EVEWLDKYFTLVDTGGIEPDSEDIILSQMRNQAMLAMDMSHVILFIVDGKAGITAADK
                     EIAQLLRKTKKPVILVVNKIDSQSQFDNIYDFYELGFGTPFAVSGANSMGFGDLLDEI
                     VENFPAGLDTEYEEDIIRVAITGKPNAGKSSILNKILGEERVIVSPIAGTTRDAIDTY
                     FEKNGQKFLLIDTAGLRRKSKIYETIEKYSVIRAMSAVDRADVVLIVIDALEGVTEQD
                     TKVAGIAHDEGKGCIFVINKWDLIEKDNKTMSNYTKDIKEKFPFMMYAPIVFVSAKTN
                     QRMNKILDTVEYVSNEHSKRISTSALNEVIGEAVMLNQPPSDKGRRLKIYYGTQTDIR
                     PPKITLFINDKDLTHFSYQRYLENKIRENFGFEGTSIKFEYRQKNKK"
     gene            complement(34440..35768)
                     /locus_tag="KR231_001097"
     CDS             complement(34440..35768)
                     /locus_tag="KR231_001097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF512 domain-containing protein"
                     /protein_id="HBH0003501.1"
                     /translation="MEVNVKKVNNIISKVYKDSIAEEIGIEVGDLLISVNEQPIHDII
                     EYRFLLSDEYLDVEIQKKDGEVYIYEIEKDYDEDLGVEFTNPIIDQAKSCRNKCMFCF
                     IDQLPEGMRETLYFKDDDSRLSFLQGNFVTLTNMSEEDINNIIKYRISPINISVHTTN
                     PELRQKMISNKFAGKLYGIMKRLADTHIEMNCQIVLCPGINDGKELDRTIKELAQLYP
                     YVNSVAIVPVGITKHRENLVELNIFNDKSASKTIEQIHQIQQKYLEKLGTRFAFLSDE
                     FYILSNSELPGYEEYEGFLQFEDGVGMIRKLKTEIEEYLNILPEKILKREKKVSIATG
                     HSAYEFIQSMADAMMDKFKNLQVNVYEIKNKFFGETITVSGLLTAKDLKEQLEDKELG
                     EALYITRSMLKADEEIFLDNIELNQLEELMRIKIIPCLNEGKDFVDKILK"
     gene            complement(36006..36206)
                     /locus_tag="KR231_001098"
     CDS             complement(36006..36206)
                     /locus_tag="KR231_001098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454951.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0003502.1"
                     /translation="MGMDIGLNEYTLAIVTLDKNMKNGGGCPIFYANDEKDLQNKALL
                     MSKCVGGMVHDMTNGTLIIVKH"
     gene            complement(36208..37140)
                     /locus_tag="KR231_001099"
     CDS             complement(36208..37140)
                     /locus_tag="KR231_001099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YIEGIA family protein"
                     /protein_id="HBH0003503.1"
                     /translation="MDRVFFVAVIIGITSRIIMLNLDQKQYPTQPNVLLSQLILAFVA
                     SSLGALLVPALINRSYTSITFLSLAAEQFRQVRANRRNTLQNLEEVQLVKRGAAFIEE
                     IARTYEVRNYMCIVTSFLTIGLYYVILAETKISEGMSLVISSICGLVLAFILKKLLTR
                     KSIGDIADVMPAEISFVDESILKVGDLKGITNIGLKSDREVYINRGVGIQIIPKNKDY
                     ANAGILFDSGQRQAIVYNIYSRLGLYGDYGEPSFVPLPRRNKEDESIMIAYLPVDKNV
                     EKVMEAVKSCPILSSSKGKNLSLKNYKIGKKGSA"
     gene            complement(37185..38117)
                     /locus_tag="KR231_001100"
     CDS             complement(37185..38117)
                     /locus_tag="KR231_001100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YIEGIA family protein"
                     /protein_id="HBH0003504.1"
                     /translation="MEESLLNANLFRHSFIVALVVGILCRGLVLRVTDKQYPSRPQDY
                     LEQIIISGLSASLGAIALPALIDKEFAALTFFAVAIQQFQGLAEQERITLKNIDNEEL
                     VPKGDAYVEEIASTYESRSYISLFSALVSSIVYIVFARKYGLSFFYCTILAIVSGAIV
                     GLIFRRFLRRNSIADIADIVPAKISFEGPILMVNGVIITNIGLESTREKYRNECLAIE
                     VIPRDLGAFGIVNDIGQRQAIIHNLFIHMGIDRDVDEVDIVAISKTNLEKSTVVIPYM
                     PILKDIDVMIDVVKSTPIIETSKGKQSDFSRKTL"
     gene            complement(38172..39461)
                     /locus_tag="KR231_001101"
     CDS             complement(38172..39461)
                     /locus_tag="KR231_001101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HBH0003505.1"
                     /translation="MEDLNSIYFFIVMLSIAIVILAVRYTITLRKYLKEFIYVSKKVS
                     NNEYHARLNISAKGELGELARNFNHMIKNMDKTLEEVQYKHLQLRSILKSISHGILAI
                     DVNGNILLINDEAKEMIKSEPNQLVEGHNINVVIKEEEILKQILQFIGSKDNETANIT
                     TKDDIVYKIKVDPVYLQNTNNVIIGSIVNIEDITKKVKLENMRSDFVANVSHELKTPL
                     TSISGFVETLKSNENIDVNTRNRFLEIIESESDRLKRLIDDILLLSFVENKDTLLMEN
                     VVVYDVFKEVYEITQHSASEKNIEVLYKCDDKSISILSNKDYIKQVFLNLVDNAIKYT
                     QDNGIVQVVVLKDEEKIVIKVIDNGVGIPKEDVERIFERFYRVDKARSRDVGGTGLGL
                     AITKHIVKSLNGCIKVKSELGIGSEFIVTILQKNFLK"
     gene            complement(39490..40182)
                     /locus_tag="KR231_001102"
     CDS             complement(39490..40182)
                     /locus_tag="KR231_001102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBH0003506.1"
                     /translation="MNTKVLVIDDEMHIVELLKFNLEVSNYEVSYSYDGFDGFIKAKE
                     IKPDLILLDWMLPNISGIEVLRKIRSDKDLKNIPVIMLTAKNMENDKVEGLEIGADDY
                     ITKPFSIKELLARISSVLRRYNLTSLGEENNILTTGNLKLDLSKHEVTKGSEKIELTL
                     KEFELLKLLIQNKGKVLSRNYLLDKIWGYEYYGETRTVDVHIRYLRKKIEDEDKSEKY
                     IETIRGVGYKID"
     gene            complement(40197..40958)
                     /gene="pgeF"
                     /locus_tag="KR231_001103"
     CDS             complement(40197..40958)
                     /gene="pgeF"
                     /locus_tag="KR231_001103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan editing factor PgeF"
                     /protein_id="HBH0003507.1"
                     /translation="MMKDYINIKNVQDIKEYVNLSGNCEELDEKLNSVNLVITCKNID
                     AKNREDMLKVCKECDLTFENLTSNSQIHSDIVNIVNKDTIGKRRDGDALITNLEKVPL
                     LLFTADCVPISIIDAKNKAIGLAHAGWRGTFSNIGHKTIKLMSECYKTVPEDLVCIIG
                     PSIGPCCYEVSEDLVEKFNTILTNNDEKFYIIKEGSYYLDLWKINEYMLRCSGVKKEN
                     IINLNLCTSCRADKFHSYRKHNKASERIGTVLQIK"
     gene            complement(40955..41416)
                     /gene="nrdR"
                     /locus_tag="KR231_001104"
     CDS             complement(40955..41416)
                     /gene="nrdR"
                     /locus_tag="KR231_001104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor NrdR"
                     /protein_id="HBH0003508.1"
                     /translation="MQCPYCNYKESKVIDSRHTDLKSIRRRRECESCKKRFTTYEKIE
                     TTPLMVIKKDNSREYFDREKIKYGLLKACEKRPVSIDEIESIVVHIENEINKCFIEEI
                     ETKKIGEMVMDKLKELDEVAYVRFASVYRQFKDINTFVNELKSILIEKGDK"
     gene            complement(41438..41701)
                     /locus_tag="KR231_001105"
     CDS             complement(41438..41701)
                     /locus_tag="KR231_001105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlmC/YmxH family sporulation protein"
                     /protein_id="HBH0003509.1"
                     /translation="MIRVSDIMEKEIINVKNGKRMGFIIDIDMDIHEGKVVSFTIFGD
                     GSRSFFSRGGDEEVIFWNDILKIGCDTIIVNIGSELSLDEFEI"
     gene            complement(41805..42578)
                     /gene="sigG"
                     /locus_tag="KR231_001106"
     CDS             complement(41805..42578)
                     /gene="sigG"
                     /locus_tag="KR231_001106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011986856.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sporulation sigma factor SigG"
                     /protein_id="HBH0003510.1"
                     /translation="MQVNKVEICGVNTSELPVLKNKQMKELLLQIKNGDEEARQQFVR
                     GNLRLVLSVIKKFNNRGENIDDLFQIGCIGLIKAIDNFDLSQNVRFSTYAVPMIIGEI
                     RRYLRDNNPIRVSRSLKDIAYKALQVRERLIRTNSKEPTVSEIAKELELEVESVVMAL
                     DAIQDPISLFDPVYQDNGDAIFVMDQVQDKKDTDENWLQEISLKEAIKKLNSREKLVL
                     DLRFYKGRTQIEVADEIGISQAQVSRIEKNALKNMRKYV"
     gene            complement(42670..43392)
                     /gene="sigE"
                     /locus_tag="KR231_001107"
     CDS             complement(42670..43392)
                     /gene="sigE"
                     /locus_tag="KR231_001107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sporulation sigma factor SigE"
                     /protein_id="HBH0003511.1"
                     /translation="MLRLKERIISFITMLGIKLKIIKPKGIYYMGGANILPPPLKPEE
                     EMELLQKLETDESVKSILIERNLRLVVYISRKFENTGIDVEDLISIGTIGLIKAVNTF
                     KLNKNIKLATYASRCIENEILMYLRKNNKKKTEVSFDEPLNIDLDGNELLLSDVLGTE
                     NDEIYKIIEEEIDRDLLVMALDRLSDREKQIMELRFGLIDKGIEKTQKEVAGMLGISQ
                     SYISRLEKKIISRLQKEMKKFV"
     gene            complement(43417..44289)
                     /locus_tag="KR231_001108"
     CDS             complement(43417..44289)
                     /locus_tag="KR231_001108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-E processing peptidase SpoIIGA"
                     /protein_id="HBH0003512.1"
                     /translation="MFKGFKGGYMVYIEYYVIENLVINYIIISCTSILTKRYNPKKNK
                     LLGASLGGAYSVAYLYPSMNILFTVPFKIIIMSIITLISFRSKSKKDYVHVALVFYLV
                     NIFISGSTYFIIYFTGISHLKISFLIACTYVSCELLKYIYKDLKMLKYIKELTKTINI
                     NLLEKSFCCKALVDSGNLLKDPISQSDVIIVKSSVLEGFIPEKLLNINYEDIDMKKAQ
                     EIIGSLDDKTSGRVRIIPYKHAGSNKTSIIIGLKADYIEVDEQKIGNIILGISNFNDR
                     EYGAIMNPNILPGF"
     gene            complement(44579..45853)
                     /locus_tag="KR231_001109"
     CDS             complement(44579..45853)
                     /locus_tag="KR231_001109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter substrate-binding protein"
                     /protein_id="HBH0003513.1"
                     /translation="MIKLKKVLSLVMVGILSVSILAGCSKKEDSKGKEGKEKLVVWSA
                     PLTDHDADAWKPIFEKFEKENNCEIEFQIVPWDNYAEKYATAISAGEGPDIGYMYAEM
                     FPQFIEMGAVEDLTPYLEKSGTSDNYLYLDDAKMMGGIYGLPIEAANPGVLYYNKDIL
                     EKLGEKPPKTWDDFKRICEKATKDTDGDGKIDQWGLAQGWGSKVFGSLNWNWYPYLWQ
                     AGGDIYNDDLKSVKFNNAEGLKAANFINDMKKYIPEDALSKDSNEMIESVFGPGKAAF
                     TIMLSSAATSTFDKSFPDLNWGYVTSLEDKTVGSFASVDDLTLMSACKNKELGFKLLE
                     YMLSKESMEAFHKEIPRAPVAKGEKYQGDPRFEEMVTRDKHMYRPLTVGPHGVEIYEY
                     LWKQLQMMIAGDITPEQALNESAKYANGLLAQ"
     gene            complement(46137..47294)
                     /gene="ftsZ"
                     /locus_tag="KR231_001110"
     CDS             complement(46137..47294)
                     /gene="ftsZ"
                     /locus_tag="KR231_001110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsZ"
                     /protein_id="HBH0003514.1"
                     /translation="MLNFDVELEECAQIKVIGVGGGGNNAVNRMVEAQLKGVEFISVN
                     TDKQALYTSKAEYKVQIGEKLTRGLGAGANPEVGKRAAEESKDEIVKLLQGADMVFVT
                     AGMGGGTGTGAAPVVAGLAKEMGILTVGVVTKPFAFEGKIRMKNAEGGIAELKSKVDT
                     LITIPNDRLLQIVQKNTSMLDAFAVADDVLKQGIQSISDLIAVEGLINLDFADVTTIM
                     KDKGLAHMGIGSASGETRAIDAARQAIQSPLLETSIQGAKGVLLNVTGGPNLGLFEVN
                     EASTLVMESCDPEANVIFGASIKEDLGDEIMITVIATGFEGLQNGALDLDTKPKSSIR
                     SSLNTTVKQAVKEIEEEVIAEEKIEPPKKASIIEEDDDESMEIPTFLRRRR"
     gene            complement(47484..47837)
                     /locus_tag="KR231_001111"
     CDS             complement(47484..47837)
                     /locus_tag="KR231_001111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="small basic family protein"
                     /protein_id="HBH0003515.1"
                     /translation="MLWVLGGLAFGVVVGYYIPFTYSMDYSIYMSVAILAIMDSIFGA
                     IKSNFEDNYDNVIFITGFIGNAILAILLTYIGEKLGVSLYYVAVLVFGMRLFNNLSII
                     RRYIISNIMNKKRKN"
     gene            complement(47936..48610)
                     /locus_tag="KR231_001112"
     CDS             complement(47936..48610)
                     /locus_tag="KR231_001112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF881 domain-containing protein"
                     /protein_id="HBH0003516.1"
                     /translation="MKKKIVILGAFILGVFISTYIKSLDPNRVYITLGQTESIESEVE
                     NTKKEIKNLKETLKKNKKTLNEYKEAKKNGNESIQTLMQKELEEVKELSGYSTVTGPG
                     ITITMRDSERELKDGQNPNDLIIHDIDILRVLNDLKKAGARAISINGERVLATSKIKC
                     SGATITVNDTTYGQPFIIKAIGDIDLLSAAINSPESYAKSLKDIYGINIKVQENNGNK
                     VNLFAK"
     gene            complement(48615..49313)
                     /locus_tag="KR231_001113"
     CDS             complement(48615..49313)
                     /locus_tag="KR231_001113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF881 domain-containing protein"
                     /protein_id="HBH0003517.1"
                     /translation="MKKRFINKSIIIGSIVLGVLVSLQLKIINIENRGMTTFKRGEQL
                     TEELKSLKKEKENLQSEVNSVKKDIEIYRGKNNEGEQDILKSEIEKYETLAGYTDVEG
                     TGIKIEINSTKDLGNSDKNDSILYNYDLLLSMINKLNSAQASAISINDQRIVSNTYMY
                     LKEDKLYMNDTVIKEPIIIKAIGDSDTLASALNIKYGIVWEIETYYNAKVKVTKEDNI
                     EINGHSDINKAEGK"
     gene            complement(49336..50076)
                     /locus_tag="KR231_001114"
     CDS             complement(49336..50076)
                     /locus_tag="KR231_001114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsQ-type POTRA domain-containing protein"
                     /protein_id="HBH0003518.1"
                     /translation="MKKRRKLNTNNVMIVLVFILMLSFCICIIVKSDLFDVKKIDVIG
                     NKRVTKSNIMKELNVNLNENIFAYNFKDMKNKLIKNPYIENVEIKRKLPNKIIISLKE
                     KEIFAVLKDEDNYCYIDKKGNLLEELRGSNESKKDLIVDVDYSIDDNKSIKFKNYKTK
                     ENVFKTLNYLKEEGIYRKINYVNLKKESNIEMLTRSNIKILLSNDDNLDYNISRVSKI
                     LIDLQNKNTNGGTINLNYGKLAVYSPEG"
     gene            complement(50346..51572)
                     /gene="murG"
                     /locus_tag="KR231_001115"
     CDS             complement(50346..51572)
                     /gene="murG"
                     /locus_tag="KR231_001115"
                     /EC_number="2.4.1.227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyldiphospho-muramoylpentapeptide
                     beta-N-acetylglucosaminyltransferase"
                     /protein_id="HBH0003519.1"
                     /translation="MKVLLSGGGTGGHVYPAIAIANKIRDEHPDAEIIFVGTEKGIES
                     EIVPKYGFELKTVTVQGFKRKIDFDNVKRVFKLFKGLEQSRKIVKKFKPDIVIGTGGY
                     VSGPVLFNASMGKIPAIIHEQNSFPGVTNKILSKTVTKVLTSFEDSHKRFPEAAEDKL
                     VFTGNPVRKEILLSRKNIARKNLSISDEKRMVLCYGGSGGSRKINDAMRLVIKNMVNE
                     DIAFIFATGKSYYDEFMGSISDINLKPYQKVVPYLEDMANALAASDLVIGSAGAISLA
                     EITALGKPSIIIPKAYTAENHQEYNAKSIEKQGAGIAILEKNLTPESLNTAVFKLLGD
                     RELLVDMANASKTIGKPEAIDLIYDEIMKVYNSTQKSTSKKTKKEKVIKEVKEIKKET
                     TPSIEGQAKVIGIKKR"
     gene            complement(51590..52720)
                     /gene="spoVE"
                     /locus_tag="KR231_001116"
     CDS             complement(51590..52720)
                     /gene="spoVE"
                     /locus_tag="KR231_001116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage V sporulation protein E"
                     /protein_id="HBH0003520.1"
                     /translation="MPKENLKKQIDIRMKTEFDGVVFYTTMLLVFVGIVMVFSASFIQ
                     SSFKHNDAYYFLKKNVIYAVLGFIVMIITSRIDYSFWKKNATAIGAIAVVLLLLVLTP
                     LGIEANGAKRWLGIGALTFQPAEIAKFATIILTAKLIEKNYDKIKSLTKGVVPLLVVP
                     GIFFALIILQPNLSTAGTVILVTFVMIFVAGMDMKIVFAMIGSGAALFAALVIAEPYR
                     LSRVTSFLDPFQDPLGKGYQVIQGLYALGSGGLFGLGLGKSKQKYFYIPEPQNDFIFA
                     IIGEELGLIGCIIVIMLFVVLVYRCVRIALKTSNVFACMVVIGIGAQIGIQAALNIAV
                     ATSSMPATGVALPFISYGGTSLTIFMGAVGIVLNISKHVKIN"
     gene            complement(52772..54127)
                     /locus_tag="KR231_001117"
     CDS             complement(52772..54127)
                     /locus_tag="KR231_001117"
                     /EC_number="6.3.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanine--D-glutamate
                     ligase"
                     /protein_id="HBH0003521.1"
                     /translation="MDLKGKKVLLVGLAKTGISTIKHLDKLGASVIVNDIKDENKLRN
                     ILDELKSINDIKYILGHHPEDVDDIDMVVVSPGVPLDLPFILKLKNSGKYIIGEVELA
                     FKLSNNPIFIGITGTNGKTTTTSLVGEIFSRAKRDTYVVGNIGNPVIDTIETSSEESV
                     LVTELSSFQLESIDEFRPKVSAILNITEDHLNRHHTMEKYIEAKANIFMNQTVEDFCV
                     LNYDDEIVKSLADKCNAKVIYFSRTKKVNGGVYLENNDIIIDIDDKIKFLNKDDVSLP
                     GGHNLENCMAAIAIAYVCKIDLEVIKDVLMTFKGVEHRQEFVRNLDNVIYVNDSKGTN
                     PDSTIKAIQSYDRPIILIAGGMDKGSNFDELLETAKSYVKSLVLLGETASNIENCAKN
                     KGFNDIHIVKDMEEAVKTSYEISKSGDIVLLSPACASWDMYESFEVRGKDFKDNVNNL
                     K"
     gene            complement(54146..55114)
                     /locus_tag="KR231_001118"
     CDS             complement(54146..55114)
                     /locus_tag="KR231_001118"
                     /EC_number="2.7.8.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-N-acetylmuramoyl-pentapeptide-
                     transferase"
                     /protein_id="HBH0003522.1"
                     /translation="MMLGITELTYTALIAFLIVIIIGPIFIPMLRKFKFGQTVRDDGP
                     QTHLAKNGTPTMGGIIMIVAILITGLTRVKVSHDMAVGLICIAGFGFIGFLDDFIKIK
                     LKRSLGLKAYQKIILQVALSFYVAFYQYTSSSSASQLMIPFTDFVINVGILYIPIMMF
                     IIVAIVNAVNLTDGLDGLASGVTLIVSVFFMLFASSIAGNTEVAVLAAATVGACLGFL
                     GFNSYPARVFMGDTGSMALGGAVVAFSVLTNSVLIIPIIGGIYFAEALSVLIQVGYFK
                     ATRKRFFKMAPIHHHFEQCGWPETRVVFIFWIITVVLAWISIIAVF"
     gene            complement(55155..56528)
                     /locus_tag="KR231_001119"
     CDS             complement(55155..56528)
                     /locus_tag="KR231_001119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-
                     alanine ligase"
                     /protein_id="HBH0003523.1"
                     /translation="MECLTIKELVLATNGKLIYGDYNDCVSDIVIDSREANAQNAFVA
                     IVGENLDGHTFMKSAYDSGCKTFIKNESNGIKLESSDINLIEVKDTSLALGDISKYYK
                     EKFDIPFIGVTGSVGKTTTRDMIYSAISAKLNILKNEKNLNNHFGVPLTLFNLNKEHE
                     CAVIEMGMSGFNEIKYLVDIVNPKIAVISNIGLSHVEKLGSQEGILKAKMEITSNFDE
                     TNTLIVNGDDKFLSTLKEKEHVYKLKTFGFNKNNDVYCESYTMEEDSLTFICVINGKK
                     EEIFIPTIGEHNIYNAMSAILVGLCLNISLDYIKKGLKNFKGTKMRLDIIKNEKLTII
                     NDSYNASPDSMDAALKILGRYKGRRVAILGDILEMGEISEYGHRLVGKSSMNNTDIII
                     TIGENSVFIGEEAKQLGFNSANIYHFENREDVFNKLNELVKTGDTILVKGSRGMRLEK
                     IVEYLNK"
     gene            complement(56695..58674)
                     /locus_tag="KR231_001120"
     CDS             complement(56695..58674)
                     /locus_tag="KR231_001120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage V sporulation protein D"
                     /protein_id="HBH0003524.1"
                     /translation="MRKVKRISKKRLVLVLILACALFFCLVIRTGYLQLMKGNWLSTK
                     ALEQQTRDIPIEPKRGTIYDRNMKELAVSVTKYTVWCKPVEVEDKKEAAEKVAEILDE
                     DYKDIYALISKKNMALVKVKRWIDDDKASQIRDAKLSGIWVAEDNQRYYPYGNFAPYV
                     LGHTSSDATGISGVEMQYDKKLKGKPGKLIVSTDASGREIPQGMEKYYEPVQGNGLVL
                     SIDEVIQHYTEKAVQKAYELNNAKKVTAIAMNPKTGDILALASKPDYDPNDSRTPIYP
                     YYQEELEKYNDKDKIKGYYQMWRNPAVSDTYEPGSTFKLITSSSALEEGVIKDGEKFT
                     CTGSVTVGGRKIKCWRHYRPHGTQEFKQAVQNSCNPVFVELGSRLGVGKMYDYIESFG
                     LMDKTGIDLPGEAKGILYNEKNVGPVELATISFGQSISVTPIQLITAISSIANGGDLM
                     QPRVVKSYTDNKGNITETVKPKKVRSVISKETSKKMLEIAESVVTEGGGKIAYIPGYR
                     LGGKTGTAQKVIDGKYAPGKYICSFVGIAPCDDPQIVVLAIVDEPTGVSAFGSTTAGP
                     IVKEIMNDSLKYLGVKPVYKEEEKAEYEKKQVKVPDVRNLKIGDAVKALEDAKLKPDL
                     DADIELPEDTKVKDIFPKPGVKVNEDSSITLYFEN"
     gene            complement(58686..59033)
                     /locus_tag="KR231_001121"
     CDS             complement(58686..59033)
                     /locus_tag="KR231_001121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0003525.1"
                     /translation="MKKNYKIHNLNEYKNKKKNNYKKRNKKKIGAKCILLIATFSVII
                     LNLCGYSKISEMKYDIYYLQKDLRKKEIVLEELKAKETEKTSIKEIELKAKELLNMDY
                     PKDGQIKYIDVDN"
BASE COUNT        18804 a        10603 c         6462 g        23315 t
ORIGIN      
        1 tataacaatt gttcctagat tatgattcga taagatagct cattaaatca taaaagtacg
       61 aaatagtctc tttaaaatat tcagttgtta ttttgtactg acatatcata taaatacata
      121 tttttatgat atatacctac atattttatg aaatttatat aaaaaattct tatttagatt
      181 atataatcta aataaattaa aattcaaaag ttaactaaac taatatttgt agggagaata
      241 aatgaaaaaa tttaggaaac ataaaagtat tagtaattgt atatctatat tgttgatatt
      301 atatctaact ttaggtagtt tgttacctaa taacatttat gcacaagatt tacaaagcta
      361 tagtggaaaa gtttgtaata ctacttacaa ggctcctata gaaagatcag aaggattttt
      421 ttaaagataa agaaaaggct aaagaatgag aaagaaaaga tcaaaaactt gaaaaatctg
      481 aaaaagaagt attaggatca tataaaaaag attctataga gataagcaaa tattctcaga
      541 caagaaatta tttttatgat tatcaaatag aagcaaattc ttgagaaaaa gaatatagag
      601 aacttcgaaa tgctatatca aaaaataaaa tagataaacc tatgtatgta tattattttg
      661 aatctccaga aaaatttgca tttaataaag taataagaac aaaaaatcaa aacgaaattt
      721 cattagaaaa atttaatgag tttaaagaaa ctatacaaga caaattatta ccatacaaca
      781 gataattcaa ctgctgttca aaatagcaat ggataatcat gaaatactgg attaagtata
      841 aacaaaggag aatctgcata tataaatgca aatattagat actacaacac aggtactgca
      901 cctatgtaca aagtgacacc aacaacaaat ttagtgttag atggagatgc attatcaact
      961 atcaaagcac aagaaaatca aattggcaat aatctatctc ctggaaatac ttatctcaaa
     1021 aaaggatttt cacctatggc tcttaacaca atgtatcaat ttagttctag actgattcct
     1081 ataaattata attaattaaa aaaattagat gatggaaagc aaattaaatt agaaacaaca
     1141 caagtaagtg gaaattttgg tacaaaaaat ggttctggac aaatagtaac agaatgaaat
     1201 agttggtaag acgatatagg tcaaattgac agtatttctg tatctattat attagataca
     1261 gaaaatgaat cttacaaaag aagaattact gctaaaagtt tacaggtccc agaagataaa
     1321 acacctgaac ttacaattgg agaagcaatt gaaaaaactt ttggcactac taaaaaagat
     1381 ggtttgttat attttaataa tataccaata gatgaaagtt gtgttgaact catatttgat
     1441 gataatatag gcaataagat taaagacagt ttaaaaactt tgtctgataa acaaatatgt
     1501 aatgttaaac ttgaaagagg aatgaatata cttataaaaa caccaactta ctttactaat
     1561 tttgatgatt acaataatta ccctagtata tggagtaatg ttaatactac aaatcaagat
     1621 ggtttaaaag gctcagcaaa tagattaaat ggtgagacga agattaaaat acctatgtct
     1681 gaactaaaac cttataaacg ttatgttttt agtaaaattc aaaaaatcct ttaacatata
     1741 attcaataat tgtaaatata aaagtaaaag aagaaaaaac ggattatttg gtactagaac
     1801 aaggatatac aaaatttagt tatgaatttg aaactactga aaaagattct tctaatataa
     1861 atatagcatt aattgatagt gatacaatat acttagataa cttatctatt acagagctaa
     1921 atagtactcc tgaaatactt gatgaaccag aagttaaaat tccaactgtt caagaaataa
     1981 tagttacaca taaaatatat tctgcagatt ttaaatttaa tccaagtaca ataaaggctt
     2041 atataaatgg tatgtatttt acaccaacat aaactaataa agaagctctc gattatgtcc
     2101 aaaaatatag agttgaagct actttacaat attttggatt taaagatatt gaaactaaag
     2161 ataaagaatt gcgtaattat ttaggagata caaatcaacc taaaactgat tgtgttaatc
     2221 ttaggagtta ttttacaggt ggagaaaata ttatgacata caagaaatta agaatatata
     2281 caattactca agatgataga gagttattgg ttcttagtgt tgattagtat caaatgattt
     2341 aaatttatcc ccacaataca atatgtattt accttataaa gtattaaaaa attaacttta
     2401 taaggtattt tttatttaaa tattatcttc ttctaatata ttctttttta gaactatatt
     2461 gtattaaaaa gataattatc tgtatcatat cacctatata taaacataaa ttcatttaat
     2521 tatataaatt taaaaaatat ttttttgata tattattgac aattttcatt ataagagtta
     2581 aaattaactc ataaattaca tattgggtat aaaatacaat gtatgttaga agttgtttca
     2641 gaaggctatg gttttctgat ttttttatgc tcagtagtga tatgcaaaaa agacaaagtt
     2701 gacatcagtt aacttttacc tttattctac tttccccaaa gtaagaataa tctaacccct
     2761 ttgagatgag caaaagctca tcttttttta ttatcaaaag atgctgtctc aaaatagaga
     2821 taatcctctt tttcattgtt gaaatgatta aaatatattt tatttcatac aaaaaagagt
     2881 gcctcatgaa caaaagttca ctttgagact ctctctttca tatcatatac ctttttaata
     2941 actttaaaat ttatttatca agtaaagata gctaataatt agtatcttct ctctataaat
     3001 ccaacttttt tataaacttt tctaagagtt tttctagctt gtttttcggc tttttctgct
     3061 cccatactat atattttttc taaataatct ttattattaa gaaggtcaac atatttttct
     3121 cttataggtc ttaaagcttc tgatactact tcagccacat cttctttaaa tatgccataa
     3181 ccctttcctt catacatgtt tacaatctct tctacactct ttttacttaa attagaatat
     3241 atatcaatta ggtttttaat acctggttgt tcatcattgt attttacaac acctaaagaa
     3301 tcagtaacac ttctttttat ctttctcttt atagaatctg aatcatctgc taatagtata
     3361 aatgcatttt catttgaatc ggatttactc atttttttag ttggctcttg caaactcatc
     3421 actcttgctc caccttttgg gtagtatcct tctggaacta caaaagtagg tgaaaatcta
     3481 ttattaaacc tatttgctaa atcacgagct aattctaaat gttgtttttg gtcatctcca
     3541 actggaacta ggtcagtttg atacaacaat atgtcagcag ccataagaac tggatatgtg
     3601 aataaacctg catttagatt tgcttcactc ttttgtgatt tatctttgaa ttgagtcatt
     3661 ctacttaatt cacccatata agtcatagta ttcaataccc acataagttc aacatgctct
     3721 ttgacatgtg attgtataaa tatagtattt ttttctgggt ctaatccaca agctatatat
     3781 tgagcaagta attctatagt attggctctt aaaactttag ggtcttgagg tactgttatt
     3841 gcatgcaaat caactatact ataataacaa tcataattgt cttgaagttc agtccagttt
     3901 tttatagctc ctaaataatt tcctaaagtc attttgcctg atggctgtgc accacttaat
     3961 ataacttttt tttcactcat ttttttgtac ctccttatat atttatattg attttaacat
     4021 atttaaaact atgtctttag agttattggc agcatcatgt acaaatacat cataagtaac
     4081 atcagcactt ccatctgcct tatcagacat tgctcttatt attacaaatg gagtattatt
     4141 taaatagcat acatgagcta tagctccacc ttccatttct ccacaatatc caccaaaatc
     4201 atttactaat tcttctttta attctttaga atttataaat ttatctcctg taactactct
     4261 tccttttaat actttatgag tctttacttc ttccacagaa gatttgtaag cagcatctat
     4321 aagtctttca tctgctttaa atacagaagt cttcattctt ggtataactc ccttagggtc
     4381 tccaaatgct gtagtgtcta catcatactg tatagcatca gttgatatta ctatatcatt
     4441 aacatcaagt ttttcgttta aagctcctgc aacacctgta ttaacaatag catcaacctt
     4501 aaattcgctt attagtatct gggcacaaag agcagagtta accttaccta tgccacactt
     4561 tactaacact acattcttac cttccaaaat tcccttataa aattctaagc tagctttttt
     4621 tatagtctct ctaatatcca ttaaatcaac taaaatacta acttcttcat ccattgcacc
     4681 tataattcct attacgttca tttttcctcc taaattttct atattaaaaa atccgtccta
     4741 aatcaatagg acggatatat tttccgtggt accacctaaa tttatataca ctcaaaattg
     4801 aatatatata tcttaatata tgctataacg tgcatacacg atatcaaata ctctgtaatc
     4861 ttaaattaca tttcatttta ctcctcaaag acccattcaa taaatacttt ttattaagtt
     4921 ctcagcatcc ttaattctct gtgcaaaaat atatttattt actatttctt atctcaggat
     4981 ttaatttatt aatttcttta ttttataata ttccttacac tataaattgt caactatata
     5041 ttataatatc caaaagaaat ttttaaaata cattttattt agctgttttc ttttcatatc
     5101 tattccataa ccatagacca gataatataa ctagaagacc tccaccaatc atctctatct
     5161 catatataac attttcagca aatgtaggca taactggtgc tgcagataat aatataccca
     5221 ctacagttac aactaaaacc atttttgcta aacctaggca agtacttgtt gattttgcca
     5281 tagtataagg tctaatttca tctggtctct cttttcttag tttaatataa gaagcatata
     5341 acaatacata tgggaataat gcagttaatg ctgtcatagt tacaagaaca ttgtatatag
     5401 catcaacaga aggcattaat gtagtcacca atagtattat agtaactatt attgcttgaa
     5461 gtataactgc tttagaaggt atcttgtgtt catttacctc tactaaacta tctggaaata
     5521 ttcctttttt aacactacca aataacattt ttattggtga tgctatgtaa agaactattg
     5581 ctcctaatac tgaaaaagct ataccaaaag ctattaattg aaccaaccaa gaaccaattc
     5641 ctaaagacgc acaaacagca gaaagtgcat ctaatacacc tttagaagca gtaatttggt
     5701 ctggtggtat tatcattgtt attgcaattg aacctaatac atataatgaa gctactattc
     5761 cagctgatat taatattgcc ttagggaagt tcttttcagg cttatctatt tctgttatga
     5821 agttagcagc agtctctgct cctgctaaac caaacattat agctgatata gcaacaaatg
     5881 catccatatt aagttttgga gtcattgaag ctattgtgta tgtagaagct atatcatgtt
     5941 ttttcaatac aaatactgct acaaatgaaa atattataag tatagcactt ggtattgttg
     6001 aacctaatgc acctgtatta gtaaatattt ttgtaaaact tattccttta gttgctataa
     6061 gagataatgc ccagaatatt attaaagata atataagtac aaacatctta ttatcagcaa
     6121 gggctggatt tcctattgta taagaaacat ttactgctaa gaaagttaaa aatgaagaat
     6181 accaaaatat tttagctgtc cagtttaacc aagaaactaa aaatccatac ttttctccaa
     6241 aggcttcctt aacccaatcg taaagacctc catcaccttt ttgatatgta gaagctaatt
     6301 cagcacaaat taaagctcct ggtacaaagt atataaatga gaataataac cacataggta
     6361 ttgcacctaa tcctaaacca aagcttgatg ctgtagattt agctatccat cttataccat
     6421 ataaagctga tacattcata aataccaaac tccataggcc tatttttttc ttttccatcc
     6481 taatttaatt tcccctctct attaattatt ttaaatttaa tttcaaaatt aataaaatag
     6541 attcattatt attaaactga tatttttcaa aatatttgca tattcaaaaa cagttttaat
     6601 aataaacctt aaatactttg aaatcaaatc ttattaaaaa tgataaattt aaaagtttta
     6661 ccactttaat tctaatgata ctaaattttt aaaattgttt caatattatt ttattataaa
     6721 attttattta ttatttttca ttagtatata aaaagataaa atacataact ttatagactt
     6781 aatttattac ttttatagaa ttttcacaat aaaaagtcat tttacttccg tatttaatgc
     6841 aaaagtagag attaaactta atataaaaaa tatataacaa atttttttta tatttctaga
     6901 agaaaagtat actctttttt gtttaataat gctaaaattg atttgtattg aattttgatt
     6961 aggaggaaat tattatgaaa gctcaaagat taaatgctgt acttgaacaa atgaaaaaag
     7021 atgatatttc tcaaatgtta gtaagtgacc ctacttctat attttatctt acaggagtac
     7081 taatccatcc aggcgaaaga ctattagcat tatacttaaa tttaaatggc aataataaat
     7141 tatttataaa tgaattattc ccagtttcag aagatttagg tgttgaaatg gtttggttca
     7201 atgatactca aaatccagta gaaataataa ctgaacatat agacaaaaat gctactatgg
     7261 gtgttgataa aaactggcca gctagattct tattaaactt aatagaatta ggtggaggaa
     7321 gtaagtttgt aaattcatct tatataatag atactttaag aatgtgtaaa gatgaagaag
     7381 aaaaagagtt aatgagaata gcttcaaaat taaatgacaa ggctatggaa caacttaaag
     7441 ctactgtttc tggtgaactt acagaaaaac aacttgttgg taaattatct aaaatatatg
     7501 aagacctagg tactgatgga ttttcatttg accctattat aggttttgga cctaatggag
     7561 ctaatccaca tggtgaacct ggaaatgcac ttgtgaaacc aggagatgca ataatcttag
     7621 atataggttg tataaaagat aactattgtg ctgatatgac aagaactgta ttctataaag
     7681 aaatacctga aaaaggtaga gaaatatttg aaatagttct tgaagctaat aagagagctg
     7741 aagctattgt aaaaccaggt gttagattct gtgatataga tgctgctgct cgtgactaca
     7801 taactgaaaa gggatatgga cagtacttca ctcatagaac tggtcactct ataggacttg
     7861 aagttcatga taaaggagat gtatcttcta taaatacaga tactgtacaa ccaggaatga
     7921 tattctctat agagccaggt atatatttac caggtgagtt cggagttaga atagaagatt
     7981 tagtacttgt tactgaagat ggttgtgaga tattaaacaa acatgacaaa gaaatatgtg
     8041 tagttggtta attctaaaat caatttgata aaattaaaaa gccatataaa aatgttttaa
     8101 acatttttat atggctttaa tttctcaatc tatgatttat ttcaatccat tatttatatt
     8161 gcagtattta tattgcagtt attaagattg caccctttga agtatatgtc cccatcactg
     8221 aaccaacttc acagattaca acatctttgt attttacatc cttttccata acttccctta
     8281 ccttttgagc cttttctggg caattagcat gtcctataaa taaaaccttt tcttctttat
     8341 ctttaatttt tgactctact aaagtaatca gctttttcaa actgtttcct tcacctcttg
     8401 ccttatctat aggagttaca acgccatctg caacttgtat tatcgcctta aaatttaagg
     8461 tatttataat ttttcctgct attggattta ttctaccacc cttaatagca ttttctaaag
     8521 tttcaagtgt tccaaaaaat ggaggattat ctttatattt atttattatt gaaacaatct
     8581 cttcaatttc ttttccttct tttattaata ttgctgcttt taacactaat tgtcctattc
     8641 caattgaccc actaagtgaa tctataacct caactttctt gttatttcct tccttttcaa
     8701 acatatcttt tgctaaaagt gcactattat aagtcccaga taatcctgaa cttatattaa
     8761 tcactaatac actttcttcc tgacaatggt atgcttctaa aaatttatca ggagaaggac
     8821 atgatgtttt tggtagtact ttactctcac tcatttttct atagaaagtt tcattatcta
     8881 tttcctttcc agatatataa ctttcttctc caaaagatac atttaaacca acaacttcta
     8941 tgttgtattt ttctattata tcatcaggta agtcacatgc actgtccact atcaatttta
     9001 ttttatccat attaacctca ctataagata ttattttatt tattcagtcg gtcgtacgac
     9061 cgatttaatt attattttat atattgaatg aaaaaaagtc aatagatata gattctcgct
     9121 ttattgacaa taaatatcca taagcttata atgttattaa tttgttataa atatacatgg
     9181 aaaggtaggt tttatgaaaa caaataatat gaaacaggct attttatcat ctgcaaccaa
     9241 tttaatagcc aaaaatggag ttcaaaatac tagccttgct gatattgcaa aagatgtaaa
     9301 tataagtaaa ggtactttgt attatcacta cgcatctaaa gatgatatta tatatgatat
     9361 tgcggatact catttagaag ttataactag tgctatacta aactgtgtaa aaaatgtcaa
     9421 atcaaaaaat tctcaaatag aaatggttaa cttaatctta gagaaaatat ctactataga
     9481 aagtcgtggt agggtacata tgtatcttat ttgtgaggca attacttcaa ataatgattt
     9541 aaaggaaaga ataagattaa aatatattga atggagaact actcttaaat ctgaaattgt
     9601 tgaatcacta gaaaaatata atagtagcga aaatgaacag gatgctgaat cattttcttt
     9661 tttactcatg tcaatagttg atggtttagt tgtccaaagt ttattaaaaa cagaaaaaat
     9721 accttatgaa aatatagctt cttttttagt taatcattgg atttaaactt aatacttaga
     9781 taattaataa aagtgaacta tttaagttat ctactttaac agttcacttt cttatttatt
     9841 ctcaataatt tttacttaaa acattcaatt tttatttaaa ccttcatgga atcacaaaat
     9901 aaaaatctct tataaattta aaatgttttt atttatgttc atgtgtatgc ccatctgaat
     9961 gttcatgacc atgtgtatgt gtatgctcat ggctatgctc atgagtacct gaaaaaccat
    10021 catcatgatt atggtcgtga cctacaccat ttacatgctc atgttcatgc ccatgactgt
    10081 gagaatgttg atgtgaatgt tcatggttat ctcctccaca gcatccttct cctccagtcc
    10141 cacaacaccc acttgtatgt ggattatgat gatttcttac tacaaatctc tctcttaaca
    10201 taattcttat acctcctagt atattattga gtacttcatg taccccatta actatggtat
    10261 acatctaact aggtataatc tcaatacata tgtcattttt taacatatat aattaacata
    10321 tataatctta aagaaattta tccttaaaac ctccaccttt tacttcttca acgttattga
    10381 cagaaataaa agcttcacta tccatatcat aaattaaatc tttaaattta cctatttcat
    10441 ttgcagatat tatgcaataa atcatctttt tcttattttg tgtatatgca ccttctgcct
    10501 ccaaaaaagt gactcctcta cccattttat tcattatcac tttggatatt tcatcatatt
    10561 tatttgatat taaaagtata gatttttttc tatcaaagca atcttttcct atatccatag
    10621 taaaagaaat tatatacatt gtaattaaag tgtacatcac caatttagct ccaaataaaa
    10681 aagctcctgc acatactaca aaaaaattaa taaataaaaa tgtatttttc ataggtatat
    10741 catactttct tttcattatg gctgctatta tatcaagtcc tccagcagta gctcttgctt
    10801 taaaagttaa ccccatacct ataccagtta atgcaccacc ataaatacac tgtagcatag
    10861 tatcatctat tgggaaatat ttagcaatat cttgtgttag ccccagtgct agagaaaata
    10921 gtaacatatt gacaaaactt attagcaaaa atttattatc aaaatacttt ctagctataa
    10981 taaatattgg tatgttcatc aagaaacttg atattccctg atttatacca aataatttgt
    11041 ataatataac acaaattcca gctactcctc cacttaataa cttggctggt gctagatata
    11101 aatttattcc taaggttgat agaatcatac ccaatataat cagacaatat tgtaaaaata
    11161 tattattatc aatacttagc tttttacttt caccatacat caaaacgcac ccctttgcat
    11221 aataaataaa ccaccctgca taacacacga taaatttaca aataaattta tcagaagtag
    11281 tttcctaaaa atattattca tcctcactta aacgtttatt cattaatatt ctatcacatg
    11341 acataaataa tttatatgat ttatacagat ttatttattg taaattttgg aatattaaaa
    11401 cattttattg aatagataat tatattacat aaaaaatccc tatagaaatc tataaactaa
    11461 tttctatagg gattttgatt aactaactat ttttttataa cttttatacc tgtcatatgg
    11521 tcatttaagt tttgttcctc taaagattta tcatctactc tgtttatttc taaagctaaa
    11581 gtttcagact tgatatattc attaaaatgg tcaacagctt tagcaatttc atcatcacca
    11641 cagtattcta ttactatatt atctaatact tcaaagttat tagattttct taattgctgt
    11701 actttagata taaattctct agcataacct tcattaatca actcttcagt tagcttagta
    11761 tctagtataa caaaaagatt gttttcaaca gatacattaa atccttcctt agcagttata
    11821 cctattaata ctaaatcctt attaaattca aaagcttcac catctaaatc aactgttaaa
    11881 gtctcacctt tttcaagttt attagcagtt tcatgagcat ttaatttact taatgctcca
    11941 acgaataaat tcatcttaga acctaataat ggccctgctt ccttaaagtt tggttttaaa
    12001 ctaaaattca tatactcatc taaatcttta gcaaatatta cctctttaac attaagctct
    12061 tcttttatta aatcaactac atcacttatt gtatcttcaa acttaccatc tactaacact
    12121 ttttgtaatg gttgacgaac ttttattctt tctacttctc ttgaagctct acctaaagta
    12181 actaagtttt tagctaaatc cattttttct tctaatttag tatctactaa ctcttcatta
    12241 catttaggat attcagctaa atgaacagat acttctcctg ttaagtttct atacatttct
    12301 tctgacatat atggtgcaaa tggagctata gctctacaaa gaccatgtaa caattcataa
    12361 gttgtattgt acactgcttt tttatcttct gttaattcag ttgcccaaaa tcttcttctt
    12421 gaacgtctta tataccagtt agataaatca tcatttataa aatcttgtat cattcttaaa
    12481 gttttattta actcaaatat agctaaattt tcttctacat ctttcattaa attattgaac
    12541 ttagataata tccatctatc aagttctggt ctatctttat attctacaaa aaattcagtt
    12601 ggatttatat catctgtgtt tgcatataaa gtaaagaagt tatatacatt cttcatagta
    12661 cctataaatt tactttggat ttcttttaat ccatccatat caaatttagt tggagtccat
    12721 ggtggagaaa catatagtaa ataccatctt aatgcatctg ctccatattg gtcaaataat
    12781 tccattggat ttactgtatt tcctcttgat ttactcattt tcttaccatc tttatcaagt
    12841 acaaggtctg gaactaaaac actcttatat ggtgcttttc ctaatacaaa tgttgatact
    12901 gcaagtaatg agtagaacca acctctagtc tggtctatac cttctgatat atagtcagct
    12961 gggaacaatt ggtcaaagtt ttccttattt tcaaatggat agtggtgttg agcaaatggc
    13021 atagccccac tatcaaacca acagtctata acctctgtta ctcttgtcat tggttttcca
    13081 catttttcac attttaagtg tatatcatct acatatggtc tatgaagttc aactgtttct
    13141 ggatttacat cttctatagc tttttcagct aattcagctc ttgaaccaac tgaatctgta
    13201 tgaccacatt cacatctcca tataggaagt ggagttcccc aatatctagt tcttgatatt
    13261 gcccagtcat ttagattttc taaccagttt ccaaatctct tctctcctac aaaacttggg
    13321 aaccatttta caccattatt attttctatt aatttatctt taagtttagt catctctata
    13381 taccagcttg gttttgcata gtatactaat ggagtttgac atctccagca gtgtggataa
    13441 ttatgaacta ctttttcttt gctatataat ttattttcag aagctagcca ttttattatt
    13501 tcaacatcta gcccatcttc cattacaaat ctaccttccc aaggagtaga tgtaaattta
    13561 ccagtttcat ctactggttg aataactggt aaatcatatc ttttacctgt gttgtagtca
    13621 tcttcaccaa atgctggtgc tgtatgaact ataccagttc catcttcagt agttacataa
    13681 tctcctactg taataaaaaa tgcttttttg tcaacttcta caaaaggcat taattgttca
    13741 tattctaaac cttctaggtc tttacctttc atttcttcta aaacttcata atcttcacct
    13801 agtactttat cagctaaagg tttagataca taatatacct catcaccttt tttaactttt
    13861 aaataatcta catcagcatt tactgttaat gaaacatttg atggtaaagt ccatggagtt
    13921 gttgtccatg ctaagaagta ttcatcagca tcttttttct taaatttagc tataactgta
    13981 ttagttttta cttctttata tccttgtgca acctcatgac tagcaagacc agttccacat
    14041 cttgggcaat aaggaagtat tttatgccct tcatatatat atccttcttt gttgaatttg
    14101 tttagtatcc accatacaga ctctatatag ttattatcta aagttatata tggattatct
    14161 aaatcaactt cataagccat tctctcagtc attattctcc attgtttttc aaatgagaaa
    14221 actgactctc tacatttttg gttaaattca gctattccat attcttctat ttgttgctta
    14281 ctagtaagtc ctaactcttt ctctacttgt atttcaactg gtaatccatg tgtatcccaa
    14341 ccagcttttc tctttacttg ataaccagac attgttttat atctacaaac tgaatcttta
    14401 agcgttctag ataaaacatg gtgtactcca ggatttccat tagctgttgg aggtccttca
    14461 tagaatacga aacttgggtc atctttccct ttttctaaag ttttttcaag tatatttatg
    14521 tctttccaat aatcaaaaac ttgtgcttct gcttgtttta cagaactgtc taccaatggc
    14581 ttaaatttcg ccatgtaaat caccctttcc tactaaatat tataattcca aaatttttta
    14641 ttctttcaca taaatttaaa tactaaaaaa ctcgccccct ttaaaccaaa gggacgagtt
    14701 ataaatcgcg ttaccaccct aattctatat gtaaactaaa tactagctac atataacact
    14761 ctaatagtat aacggtacta accggcacag cttagtagaa tttaatcgtt cagcctgcag
    14821 ctcaagagtg atttttatct ttataaattc attggttctc agcataccca attctctgta
    14881 aaattatcta aagataaatg tctctatcaa cgcttttaaa aatttatctg tgtttatatg
    14941 aaattctata acaaataatt tgaatagtca atatattttt gaaaaatata ataatttcta
    15001 tttttcttac atttttatcc tatttttaat ctttgttata gatttctcaa actcacacaa
    15061 ttattctaca taaaaaataa acaaattaca agcttattct aaagttgtag cagcttcatc
    15121 attactataa ttatacactg ttgttccttc aaatgcgttt acacattttt catctacatc
    15181 ataaaaaatc tcatcaacac ttcttatttc atcttctaac agtgatttaa atttatttct
    15241 aaatatctta aattctttga ctaaagcatc atactctttt cttatctcta taacacggtt
    15301 attagcttgt tctataattt gtctagcttt taaatcagct tcttcaacaa ttatcttagc
    15361 ctttttatta gccgcgctac aagtgtcttc tgctgcactt tgagcagtta ttaaagtagc
    15421 ttttagtgtt tcttcaatat tttcatactt gtttacttgg tcttgatata accctaattt
    15481 ttctttaaga gctgtatttt ccctacatag agattcataa tcttccttga tgatatctaa
    15541 aaattcatca acctcttcat ctctataccc tcttaaacct tttttaaact ctttattttc
    15601 tatctcaatt ggagttagca ttacatttcc tcccagctat aatttaaatt agtccttata
    15661 caattaatct tgcttgaact tttatttttc cttttttagt aatatctcct atttgtgtta
    15721 ccttagctct tcctttgcct ctaatagaaa tcaaatcatc attttttact attttagaag
    15781 ttgaagttat cttttcataa ttgacatgga ctttttctcc atttatgtat tttgcactat
    15841 cttgtctaga tatattgtaa ataccactta tcacacaatc taacctatct gaagatactg
    15901 taaatgatac ttctttatat tttgaagaac tattaacaat attttctctg gaaatttcct
    15961 ttacaattac attatttctt gaaacctttt ctaagtttac aattataaaa tcgcaaatat
    16021 cactacttac aactacttga caaaagctat catgtataat tatatctcca attttttctc
    16081 tttttatacc tagacccagt attgacccta agtaatcttt atgagatata tttttaaatt
    16141 tgaaattccc ttctatttgt aaaaatctaa gagtatcttc tatatcttca tattccatgt
    16201 aaaatggata aataaataca gtgcttcttt cagcttgttc ataacctcca tccacactgt
    16261 attttatttc atttgtagaa tttaatattg ctacagcatt tttcacttca tatggattaa
    16321 gaaactccgt agacttaaca tcatagtttt ttatacaact attagccttg tctatcactt
    16381 taaacatttt atttttcaag tctatatcct ttatgtgatt tgttagtttt aatttatcca
    16441 tcctatcacc ttagaatata accaatacta attgtcttag gaacatcaat aatactattg
    16501 caattaaagg agaaaaatct ataggtccat ttgtatattt atacattata gaccttattg
    16561 gcccttctat tggctctgta agattttcca aaatatcaaa aattttactt tgtcttccat
    16621 ttggaaacca agtcatcaag ctttttataa ctatcatcca tgctattata tctaaaagat
    16681 aataaagtgc aattcttatt gttcccatat attaaccgcc tttttactat ttattttgcc
    16741 aagggaagaa tgctttactt tctaattctt ttttcatatt tgcatctata tccacattat
    16801 taggagctag tataaatatt gatttagaaa ccttttgtat acttccatct aagacataaa
    16861 ctgccccatt cataaagtta aatatagatt tacgaacttc agaattagtc aatccttcca
    16921 aattcactat aactgccctt ctttgtttta gatggtctgc tatagttgca gcttcatcat
    16981 aaaccttagg ttcaactatt acaactttca tttggctagt tgtatgtaaa tttacaattt
    17041 tatttgcttt tgcagtacta aagccactgt tcatttcttc ttcttgaact atatcgtcca
    17101 tgccactttc atattcatct tcaatgtaat cttcttcttc atcaactatc caattcttaa
    17161 atttagatat tattccattt gacattatta acttcctcct taaaatttat tcaaatttga
    17221 gtaattattt tttattgtag tttctttctc caaagattga tgttccaact ctaacaatgg
    17281 tagccccttc ctctatagca atttcataat cgtgactcat tcccattgac aaaacatcca
    17341 tccctacatt agggatgttt agttctttta tttgttttga taaatcttta agacctttaa
    17401 atacacctct tatctcatct tcatcttcta taaaaggtgc cattgtcatt agacccttta
    17461 tttttatatt tttatatttt tctgacactt ctttgacaaa gtctacaact tcttctctat
    17521 caagtccatg cttagactct tctttagata tattcacttg tactaagcaa tctatttctc
    17581 tgtttatttg ttctgcacgt ttttgaattt cttcgcataa tgcaattcta tctaaagagt
    17641 gtatcataca aactttatcg attatgtact taactttatt ggtttgcaaa gttcctatca
    17701 ggtgccagtt taatttatca cctataatat catactttct agctaattct tggggtttat
    17761 tttcaccaac agaagtgatt ccttccctca ttgcctcatt aactaagtct acatcaacag
    17821 tctttgtgac tgccaaaagg gtaatctctt tgctgtctct atctactttt tttgcagctt
    17881 tatcaatttt gtttcttatc tcagacaaat tgtctttaat agaacccatt attatcacct
    17941 actttatcct tatatttgtg tttatactgt taggtcttaa aattattttg tcatatagat
    18001 taacacttgt aactccattt atgtcatttt tataataatc cacaaataca gaagattcat
    18061 tctcataagt tattccttct aatatgacaa attttacact ttgtgattgt tcatcaatta
    18121 catatacacc acgtttattg tcttttgttt ttatagaagt tttaggtatt tttaaacatt
    18181 ccatctgatt atatattata tcaaattctt cgacacttgt atcctgattt gcaacaattt
    18241 ggttacttat ttttaatttt accattattt tattattatt ttcatatatt ttgtaaactt
    18301 ttgcatctaa tttttgctca tgatattcaa ttattacatt ttgatttttt tcaaagttat
    18361 tagaatcttc tttactgatg tatgtagata gataattact ctggtcattg gcatcttttt
    18421 ctatagttcc ttttacatga atctttgcat caactttttc attttttaac accaacgtat
    18481 ctacattttt gctaattatc attactaata tattaaatac taaatatata agaataccaa
    18541 gtatcactaa tctggtatat tttacctttt tcaaagactc tccccctata aaattacttt
    18601 cattataagt acttcttcta aaaaatgttt attccttttt tataagctaa tattttacgt
    18661 tctaataatt attttttcca tattaaattt attttttatc aatcttccta tacaagactg
    18721 cattatttat atataattgt attataaagt ataagtttaa tttacatttt atacgttaag
    18781 cttactttat atgtttttat agttattttt atttttagat gcaatataaa accaattaag
    18841 atttaaaata acttttgtta tgttgacatt tatttaggta atcatttatg aattaggata
    18901 acgttatcat aacaaaagtt tatgtcctaa aaaaaataca aggaggattt tcttatgtca
    18961 gaaattttat taggaacagg tttactttta ttggttctat gttgtttcac aatttttagt
    19021 tacaaggccc catatggtat gaaggctatg ggagctctag caaacgctgc atgtgctact
    19081 ttcttagtag aggcattcaa cctttcttta cttggtgatg ttttaggtat ggaatttttt
    19141 agaagtgttg gagctgctaa tggtagtctt ggtggagttg ctgctgctat acttgtgcct
    19201 ttagccttag gtgtatctcc agtttatgca gttttaatag gattatcttg tttagatttt
    19261 tctatattat ctggattcgt tgctggatac tttgtttctt tcttaattaa gtttatagag
    19321 aaaaaagtgc cacctggagt ggatttagtg gttgtaattc ttctatgtgc accgctatct
    19381 cgtcttatag catcaaatgt agacccatta gttaatagta cactactaca aattggacaa
    19441 gttttgatag aagctaccaa cattagccct ataataatgg gaattatact aggaggtcta
    19501 ataacagtag ttggaacgtc tccacttagt tcaatggctc ttacatctat aattggtctt
    19561 actggtcttc ctatggcaat aggagcatta ggtgcttttg gttcagcttt tatgaactca
    19621 acactatttg caaaattgaa attaggttct aaaaaagata ttatatctgt tgctattgaa
    19681 ccattaaccc aatcagacat aatttcagct aatccaatac ctatatattc tactaatttc
    19741 tttggaggag ccttttctgg tatcattgta gccttgatgg gtcttgtaaa catgacacca
    19801 ggtacagcta cacctgtggc tggttttgct ataatgtttg cttataatcc agttcaacaa
    19861 gttcttataa cagctggttt atgtgcttta ttcaatgtaa ttgcaggatt tttaggttca
    19921 aaaatattca gtacctttaa agttcttact gctggtgaaa tacgtggtac tgatgtagaa
    19981 gaagaaattg cttaaaaaac aataagattt ataaatttat atctcaagta gtagagtttt
    20041 atattgtagg caattttatt aattgcaaac gttttatttt ttatttatgt ttatgattat
    20101 tatgtgtgtt gaatatttag ataaattttt atttattatt tttatttaga tttttgttta
    20161 gttttttatt tggttgatat attaggaata aaaattagta tagtttatta ctagttagat
    20221 agcataactt tttagataca taaaaaattt tatattaatt agatattatt aaaataaaag
    20281 cgatacatga atttttaaat gtccatgtat cgctttattt ttgccataat cttaacaact
    20341 gatttttaaa gtttattatc ttaacaaagt tcattatctt atataatatt taaatgcata
    20401 gacttcttta atttaaccat ctaaatattt aattaaatat tattatatgt aatataacta
    20461 atttttaaat gaatgtatag gagctggaat ccttcctcct ctttgagtaa ataattcaga
    20521 tgaatttgta tttataggca ttactggtgc tcgtcctaaa agtcctccaa attctaccat
    20581 atcacctaca tcacatcctg gggctggtat aattctaacg gctgtagtct tattattaat
    20641 catacctatt gctgcctcat cagctatcat ggctccaagc gtacctgctg tagtatttcc
    20701 tggcacagct atcatatcaa gacctacaga acaaatagca gtcattgctt caagcttatc
    20761 tatacttaaa gcacctttaa taacagcatc aatcatacct gcatcttcag atactggtat
    20821 aaacgctcca ctaagtcctc caacatgtga acatgccatt actccacctt ttttaacagc
    20881 atcatttaaa agtgctaatg ctgctgtagt cccatgagta ccaacaactt caagacccat
    20941 ttcctctaat atatttgcta ccgaatcacc aatagcaggt gtaggagcta gtgataagtc
    21001 tattatccca aatggaacat ccaatctact agaagcttcc tttgccacaa gttgtccaac
    21061 tcttgtaatt ttaaatgcag tctttttaac tgtttctgaa acaacatcaa aaggctctcc
    21121 ctttactttc tctaaagctc tcttaacaac accagggcca cttacaccaa catttataat
    21181 tctatcagcc tcaccaacac catggaaagc tcctgccata aatggattat cttctactgc
    21241 attacaaaat actactaatt ttgcacaacc aaaacctttt gcatcttttg ttaattctgc
    21301 agtttctttt atgatttctc ccatttcttt cactgcatcc atatttatac cacatcttgt
    21361 agaacctaca tttactgaag cacatacttt attagtactt gctagagctt ttggaattga
    21421 cttaattagt atcttatcac cttttgtata tcccttttga actaatgctg agaatccacc
    21481 aataaaatct atacctaaat cttctgcagc cttatccaat gtctgtgcaa actttacata
    21541 gtcattttca tctgttgcac ctgcaataat ggaaattgga gttactgata cccttttatt
    21601 tacaattggg ataccaaatt cacgctctat atcttttcca accttcacca aatctttagc
    21661 agaactcata atcttattgt atattttttc tctagcttta tctccatcag ggtctataca
    21721 atctaataaa gaaatcccca tagttatagt tcttatatcc aactgttctt catctatcat
    21781 ctttattgtt tcaagtatat ttcctacatt cactattatc acctcccctt actgtctact
    21841 acagattatg cattgaatta aatatttctt ctcgctgaat ttttacatcc actgataatt
    21901 tcttacctct ttcaaccaag tcctcaaccg ttttctcaaa agaatttaat gatttctcta
    21961 aatcaactat cataatcata gtaaaataat cctgtaatat tttttgtgat atatctacta
    22021 tgttgatatt ttgcttgtat aattcatcac taattcctgc cactatacct ggtttatcct
    22081 ttccaattac tgttaaaatt gctttcataa taatatcctc ccttattttt ttataaatct
    22141 tatattttta caaattgaac tatgtgttaa catatatttc atttatttgt tagtaaacca
    22201 ctttttatgt atatatttaa tatattttaa tacctataca ttcatttgtc aatttttttt
    22261 caatattcta ttatttttat actatttaga aaattcatat attatatatg ttttctcaac
    22321 aacaaataca gttttcataa taatgaaagg tattacttag caatctcatg attttctaaa
    22381 taataccttt ctaaaaatta tttttttaat tttatgaatt taattatact ttttctagta
    22441 tcaggattta caattaatat agaaccaatc ataattggtg ttagtataca aaataaaaaa
    22501 ataatatctt tttttagatt atattcttta gattctaatt tataattatt atttattatt
    22561 ccatcataat cacttatatt tgacttattt ttatttgtat cttgattttt gttagaaata
    22621 ctttccctat aaggaaaaga atgttcattg gtaccaaata ctgattttga gcttaaatca
    22681 taattatcat cattttctgt aattgaattt ttattgtaaa atcctttttc tttatcagaa
    22741 ttattttctt tattaccgtc tttaggtata tcatgaggat ttttattttc attgctatca
    22801 gtacttgatt ctacatcatc tttaggagta tttggttgtt tctcatcaga attatcattt
    22861 tcattattat tattttcatt attattgttt tgattgttat tactatcatt attttcattt
    22921 ccattattcc catcttgatt gttatcatcc tcatctctat ccgggtcgtc tctacctcct
    22981 cctccacggt caccatcaat atcatcattt tcccgttcat catctggcgt ctcttgattg
    23041 tctccgcctc ccattataaa tcctggttta aaaactatat ttgaataccc ttcttttaat
    23101 cctcctacca cttttactct aaaacaacgc aacttaaaat cttcaaaaaa aagtatagct
    23161 tgatctctaa tatcctcctg ttcttcagat atccaattga ttccatcgct tgaatattca
    23221 acaaaaacct tacttgcact atacggcata tcataaaata aaacagctac atatccattt
    23281 tttgtatttt gaaattccag ttccaaattg tctattggtt ttttctctat aacagataca
    23341 ttcaaaatag gaactacatc atcatttatt ataatttttt ctttatttaa catttctgtt
    23401 ttaaactttc ctgttatatt aaaattttct cccttttcca acttttcata ataatcagta
    23461 aaatcccatt ctacatctat atcaagtcga ttaccactag atgtttctaa taccatatat
    23521 ttgggaaatt ttatattttc tattttatca tctttactta cttttatttc atcactaaat
    23581 acaccaattc ccctatgaca acatttcaca atatcatagc cagaatcttc agctatagaa
    23641 ggtataagct cattataatc atcaattata taaactttct tactttctga tataattgat
    23701 tgtgccaact tattattatc tcttagtaac ccactttcat tgttgctact atatgctttt
    23761 attgaagttt cttctatctc aacatcacct ttagaataaa cacctatagc atgttctcca
    23821 ttcacttcaa tatccttatt tagtattcta atatcatttt cagtataaat tcctattgca
    23881 tcttttccat ttgcctttat tttttcaaca gattcgtagg atgatttaat atgtaagtct
    23941 cctccttctt caacgtataa ggctgtccca tcagtagcaa ttatgttgtt tataccaata
    24001 cttatacttc caccattttc tatatgtatt actccttctt ttcctccttc acctattata
    24061 ttcaattcat tatcatcaat aataaatctc ccatgatttt ttatcaatat tttatatttg
    24121 ttggtatcta ttgtaaaatt actgtcataa ggaatataaa atctaaactc ttcatctatt
    24181 accatatcac aagaaagagt ataaactatt tcttctttat tatttttatt ttcttgaacc
    24241 cacctttcaa aatcttcaag acaattttcc tcttgtccaa aaactttatg tggaaaactt
    24301 ataaaacaca aaactattat actcataaaa ataaatatct catacttttt catcttacac
    24361 tcctagaaat ttttagcttt gaaacaatcc tgtcgaaaca tatacttcac ccactataat
    24421 ttttccacaa ttatcaatta ttgtcaattt atataagtat ctttattaat tgttataaat
    24481 aaaaagctac ttactaaagc aaacagacgt ttcactttaa taagtagcta tatttttata
    24541 acaaaatagt tataatatta gaacttcctt catttacaat tttttgtaaa gtcttttgca
    24601 ttttaactct tatctcttct ggcatagtat ataatttact ttgtaattgc tcttttacta
    24661 agtcatgtag tgatttacca aacatatttg attcccataa atctgctggt tgctcttcaa
    24721 atacttccat aagatatttt atcatctctt caccttgatt ttgatttcca actattggag
    24781 aaacctctgt agatatatct gcttttataa tatgaagtga tggtgcattg gcttttaact
    24841 tgataccata ttgttttcct tgtttcatta tttctggttc ttccagacta agttcttcta
    24901 aggaaggagc tactactcca tatcctttta tcttggcatc tattaaagca ctttctattt
    24961 tatcatactc atttttaact ttagatagtc tagttatcag actaagcagt tgataatctc
    25021 cttcaatttt aaatccactt ttttcttcaa ggacattata gaataaatct tgctttgtct
    25081 gtaaatcaat atttataaca ccttctccta gctctacatt atcaacacct gtatcttcca
    25141 aaaactctaa ctcagaaaat ccttgtataa taccttctat atcccttatt ttacctatat
    25201 ctataatact ttgttttaat gttgttatta tgctactttt tatccaatga tttctttcaa
    25261 gaccttcaac ccattttggt aagttgattc ttatttctgt aagtggaaaa tcatataata
    25321 cagcttccat aacctcctct atatcttctt cttccatttc aaccacattc attggaagaa
    25381 ctggaacttc atacttttct tccaattcac ttctaagcat actcgtttcc tcactttttg
    25441 gacttaacgt atttaaaacc actgcaaatg gttttttaag atttttcaat tcttgtataa
    25501 ctctctcttc tggttctaca tagctttttc tgtcaattcc agtaactgaa ccatctgtca
    25561 agacaactat ccctattgta gaatggtctt ttataacttt tttagttcct atctctgctg
    25621 ccttttcaaa tgtcatagct tcttgtgacc aaggagtgga tactaatctt tgttttccac
    25681 cttcctcatg ccctaaagct ccttcaacta tgtatccaac acaatctacc attcttactt
    25741 ttaaagatac tgtgtctttt atttttattt ctacaccatc tgctggtaca aattttggtt
    25801 ccactgtcat tatcgtttta cctgaaccac tttggggtat ctcatctctt gttctatcct
    25861 ttttaaattc attgtctata ttaggtataa ccaacttttc cataaatttt cttataaaag
    25921 ttgattttcc tgttcttaca ggtccaacta ctccaatata tatatccccc tgagtccttt
    25981 tggatatatc ttcgtatatg ttattattca tattattcct cctatacatc taatcttatt
    26041 aaattatatt tagagttaag ggttaatatt cttaaaatag aaaaataaag accagcaata
    26101 ttaatttaat ttacatatag aaatttgtaa atttcaatgt aaattaaatt aatattgctg
    26161 gtccaaatag tagtgtatta tattaactga ctttagtagt attttcattt gaattattat
    26221 tcatctcaat aagttcttta cgtctttctt ttgtcatgtt catccatata aatgtaaaca
    26281 ccaatccaat tatggctact atagtaagaa ctatgaagta gtacctatat ccagttacac
    26341 ccggaaatgc atccaatatc ttccctgctg ctaaaggaca aagtacttct ggaagatatc
    26401 ctaatgtagc aactattcct atagcagttc ctgatattga taatgaataa ttaccttctt
    26461 caagtaacga atagtgtaaa ccttgaattg catacataga tacatatatt gcaacacatc
    26521 caatcaatag tatataaatc atagatgatt ttgttggtgt aaatattaca cctaaaagac
    26581 ctgcaatcat aagtataaat ccataagata taatctttga tgaaccaact ttatctccaa
    26641 gtaatccaga agcagctgat gctactggtc tacaatactg agctaatatt gagattgcag
    26701 atgcaaacac cacagtagct ccaaatgctt cagttgaata aggcgtaaaa taataaaatg
    26761 acatattagc tgaatatgaa caaaacatta ttattgttat tatccatgta tgaggcattt
    26821 ttattactgc aaaaaaggct tctttatcaa attttgctga tacctctttt tcattatcct
    26881 ttaatttgaa aaatactaat actccaacta ttacatttat tgccgagtat aatactataa
    26941 tagctgtaag accagattta tcacttactt ttgatgaaat atacccaaat agtatcaata
    27001 ctagagatag atgaattgca ttggtaattc cacgaccact ttccataaat ccaaaagctt
    27061 ttccttgttc attttcagat gctaacattc taacagcttt tacaagagct ggccaaaaag
    27121 taagtattgt tgttattccc cataaggcat ggattaaaaa cacaacaata tatggaggat
    27181 aaagtgttaa tacaagacca gatattcctg taataattaa agaacctgaa agcaattttc
    27241 tggctgaaat acggtctgct aaaaaaccac caaaaaggta tgataccatt gcaagtagac
    27301 cataaatact tcctaagctt cccatttgtg tatttgtaag attaaatgct tgtgcaaaag
    27361 tatcataata ataattcttt aaatatggta aagcatatat aaatgctcct gctacaaaga
    27421 gtattatcaa gactttgaaa tttttccaaa tgcttggttt atttacttca actgacatac
    27481 ttcctcctta tgtaaatacc tgtaaatttt catgataatt aattattgct tattgtattg
    27541 tttattcaat atttcggaat atttattaat atattaggtt aatctatcaa taatttatgg
    27601 tgagttatga gctaaaagta aactctttta gctcaccata ataattatat ttttatttat
    27661 actaacgtcc agagttatta gatatctttt tttcatagtt cttccatagc attaaacctg
    27721 ttattataac aaaaagacct cctcctatca tttcaatctc atagattata ttatctttta
    27781 aagtctccat aactggtgcc gttgagaaaa gtatgccaac tacagttact acaagtacca
    27841 ttctggcaat attgatacaa actgaatcac tttttgcaat tgaatatggt ctttcttcat
    27901 ttggtcttgt ctttctaagt ctaatataag atgtaaaaag caagacatat ggaaataatg
    27961 ctgttaatgc tgtcatagta acaagaacat tgtatatatt atctactgat ggtaataagt
    28021 ttgttcctac aagaagtaga ctcactatta tagcctgaac tattactgca tttgatggta
    28081 tattgtattt atttgtaaca gtcaattgct taggaaatac accttctctt acatttccaa
    28141 aaagcatctt tactggacct gctatataaa gtattaatgc tcctagtact gataaagtta
    28201 ttccaaatgc tactattctt ataaaccaac ttcctatacc taaatcttgt gcaactttag
    28261 ctaatgcatc tagtatccct gtagatgctg caattttatc tggaggaagt atcattgtta
    28321 ttgctactga acctaagata tagattcctc ctattaaaac agccacagtt aatatagctt
    28381 taggaaagtt tttcttagca ttatccattt cggttatgaa attagcagtc gtttcagctc
    28441 ctgataatgc aaatattata gcagatatag aaactaatga attggcatct atttttggta
    28501 ttatattttg gattgtatat atcgatgctg atggagcttt tttgagaata actacagaca
    28561 taaatgccat cactataagt aatatagcag gaattgtaga acctaatgct cctgtattcg
    28621 taaaaaattt tccaaatgcc atcccacgag tacttactaa ggacaacagc caaaatatta
    28681 tgagtgaaag tgctaaaata aacatcttat tgtttgataa atctggattt ccaagcatat
    28741 atgcaatatt tatagctaaa aatgtcaaga aagaagaata ccaaaatatc tttgatgtcc
    28801 aatttagcca tgacaccata aatccccact tctctccata agcttgttta acccattctc
    28861 caagtccacc atcttttgga tatgttgcag ccaactctgc acatataagt gatgcaggaa
    28921 caaagaatat aaaagcaaac aataaccaaa ctggtataga accaagaccc aatccaaaac
    28981 tagaggcagt agatttagct atccatctaa tcccaaatag tgctgatata ttcataaata
    29041 ctaaatccca aaatccaatt ttctttttca ctgtaattcc tccaatttca aatttattca
    29101 aactcataca ctatgtattg atttaaatat caagtataag ttcttcaaca cttcttggat
    29161 aattagttat aattgtagca ccattcttac ctactattgc tgtatctgag tgtctaaatc
    29221 ctccaactcc aggtatatat atccctggtt ccatagaaaa taccattcct tcttctaata
    29281 ttaattcatt gtcaaatctt aaatatggct cttcatgttc tgacaaacct aaaccatgac
    29341 caattctatg atttgaatat aactctagac catactttgc aacaacagct cttgctgctt
    29401 catccaccat tcttgctggt ataccagctt ttattgtatc taatccagct tgttgagcct
    29461 ctactgcaat cttaaacact tctttttgtc tttctgttgg tttgcctata ataaaagttc
    29521 tttcattttc tgctctatag ttttcatacc aaacctgtct actatgtatt actatatctc
    29581 ctctttgaag tattctagta ttagaatcta aatgaggttg tgctgttcta tcaatccctg
    29641 aacaagtcca gtttgcaaat cctatatatg tatcaggata attttcagaa acatatttta
    29701 gtaaagcatt atccccttca acgtcaaact ccaattcact catcccaact ctaacatttt
    29761 ctaaagaccc ttttattcct atatcagata ggtaacctgc tatcttcaaa aattctattt
    29821 cttttgcatc ttttacatat ctcatttcaa atattttact tccaacatct ttgatagcaa
    29881 atgacttatc agttatatac tctgaaaagc ttgcagatac tatatctttt tctattccaa
    29941 cagttgttcc tttagggtat ttatttaaaa ttatatctaa gtaatgttta tgtgatattc
    30001 catgttcttt catttctggt atttcataat acacatatac attatcaact tttgcaactt
    30061 ctttagcatg taattcttct aatccaggta ctattaattc tattttatct tgagttacta
    30121 ctgttacaat tggtctagaa taagttattg ctttaaatcc actaatataa aattgattgt
    30181 ctggttcaaa tattaaagca atttcaatgc ttttttcatt catgtacttt ctcaatcttt
    30241 ctagtctcat attatttgac ataatgcacc tctttcttaa tattcagata atttattcaa
    30301 tacaacaagg atgaatatat tattttaaaa ttcttaatat ttttagtact tgtcgtattt
    30361 gtatgtaaat taattttatt tgtgattatt ttatcataat catgattatt ttgtcaatca
    30421 tgattttatt ttaaaaaatt ttttatattc tagtgatttt aaattatcta aaatataacg
    30481 agtatacatt gtattttgta atattattct tgatttatgg taagtttaat gataaaatca
    30541 cgattatata aactatattg attatttgta ggtgaataaa atgacaaata aagaattaca
    30601 aaagaaaagg atattgatgt atttcataga agctgctcaa aatattatgg aaaacgaagg
    30661 tatagaaaat attacacttc gtaaggttgc agatatggct ggctataata gttcaactct
    30721 atataaatac tttaaaaatt tagaccattt aatatcattt gcatctataa aatattttaa
    30781 agattataac ttgaatattt caagatgtat agaaaatgtc aatgatgaat ataagaaata
    30841 tataattatg tggaaattat tttgtaagca ttcttttgat aatgctcaag ctttttacca
    30901 ggtatttttt aacttgtcta gtgatgaact tagctatata acaaaacaat attatgatat
    30961 gtttccagaa gatttaggta ttcatgatag tgacatatct ttaatgatta caggagaaag
    31021 tataaaggaa agaaataaga tactattaaa caatcttgta gatactggat atataccagc
    31081 taaagattta gacataatca atgatataat tatttctttt tatcaaaatc tattattctt
    31141 aaaaaagaac acaggaaaaa attctgatga tgatgaatta actatgaaaa tgatttcttc
    31201 tattgaatac ataataaaac atgctaaata aaattaaaat atggctgtct caaaatagag
    31261 ataagccttt tttattgttg aaataataaa aatatattta atttcatata aaaatgagtg
    31321 cctcgtaaac taaaaagttc attttgagac acccctaaaa taaatttatt atttattata
    31381 caatagttta tatatcatca cctaaaacta cttcttccat ttcatgcttt ttacttctca
    31441 tcattagttc tattccaact tctttaggat ttgaaccttt ctttattaca gaatatatag
    31501 cattagttat aggcatatct atatctaatt tttcagcaac atcatgtgct acttcagtag
    31561 cagttatgcc ttctacaacc atctttactt cttttaaagt atcttctaaa ctcatccctt
    31621 tacctatgag tataccagct cttctatttc tactatgcat acttgtacaa gtaactatta
    31681 aatctccaat acctgaaaga cctgcaaagg tagacatatt agctcccata gcaattccaa
    31741 gtctgctcat ttcactaata cctcttgtca taagggcagc ttttgcatta tcaccatacc
    31801 ctaatccgtc acatatccca gctccaaatg ctataatatt ttttaatgct cctccaagtt
    31861 ctactccaac tatgtctgga ttcgtataaa ctctaagttt agggctcata aacaaatctt
    31921 gtatcatctg tgctattttt aaatctttag aagcaactac tacggtagta ggaatatccc
    31981 ttgctacttc ttcagcatga gatggcccag atagtattac atatggattt tgtggtaatt
    32041 cttcttcaca gacttgtgat aatctaagcc cagtcccttt ttcaagacct ttagctacat
    32101 taacaataac ttgtccttct tttataaatg gttttatttt ttggcaagta cttcttacag
    32161 cctgtgatgg aactgctaaa actattacct tacaatcttt tatagttttt tctatatcag
    32221 tacttatagt tatattattt ggaaataata ctcctggtaa atagtctgta ttttctttag
    32281 ttctgtttat ttttttagct tgttcctctt ttcgagtcca catgctcaca tcattacctt
    32341 tttttgcaag ccctaaagct aatgcacttc cccagcttcc agtacctaat acacatactt
    32401 tctccatgtt taacaccacc tgagtataat atatttacta ttctttcttt tgaccaattt
    32461 ttctctctgt cccatttaat aatcgcttta tatttgctct gtgattatat attactgatg
    32521 cagttaagaa cagagctact attaaaccag ctttattttt taccataatc ataaatattg
    32581 gtgaacatcc tattcctaca acagaaccca atgaaacata ctttgttata gctaccacca
    32641 atataaatac tgctagacac attagtgtta ttactggatt tacagctagc attgccccta
    32701 gtgaagttgc aacacctttg cctcctctaa atcctaaaac cgctggccaa ttatgacctg
    32761 ctacaacaca tataactgcc agatatccag ctaaaagagt atctattcca accaatcttg
    32821 ctgcaaattc tgatattaaa acagccatta cacctttaag aacatcacct aaaaatgtca
    32881 ttgctcctgc tctttttcca agtgtcctaa gtacatttgt cgaacctgca ttaccagaac
    32941 cttgagtcct tatatcaacc ccagcaattc gctttgcaac tatgtatgag gtagatatat
    33001 ttcctaaaag atatgcaact acagcaataa ttatataact aaatatctcc actgaatttc
    33061 ccccctttag ttatatttta agatatttat tttttatttt tttgtctata ctcaaacttt
    33121 atggaagttc cttcaaatcc aaaattttct cttatcttat tctcaaggta tctttgatat
    33181 gagaagtgag ttaaatcctt atcatttata aacaatgtaa ttttaggagg tctaatgtca
    33241 gtttgagtcc catagtaaat ttttaatctt ctacctttgt cagatggtgg ttgatttaac
    33301 attacagctt ctccaattac ttcattcagt gctgaagttg atattctctt agaatgttca
    33361 tttgacacat attcaactgt atctagtatc ttgttcattc tttgattagt ttttgcagaa
    33421 acaaatacga ttggagcata catcataaat ggaaattttt cttttatatc ttttgtgtaa
    33481 ttactcatag tcttattatc tttctctatt aaatcccatt tattgattac aaatatgcat
    33541 ccttttcctt catcatgtgc tatacctgca acctttgtat cttgttctgt tacaccttct
    33601 aaggcatcta ttactatcaa tactacatct gctctatcta cagcactcat agctcttatt
    33661 acactgtatt tttctattgt ctcatatatt ttactttttc ttctaagccc tgctgtatct
    33721 attagaagaa atttctgtcc atttttttca aaataagtat caattgcgtc tctagtagtt
    33781 cctgcaattg gacttacaat tactctttct tctccaagta tcttattgag tatagaactt
    33841 tttcctgcat ttggtttacc tgttatagct actcttatta tatcttcttc atactctgta
    33901 tctaatcctg ctggaaaatt ttcaactatc tcatctaata aatctccaaa tcccatacta
    33961 ttggctcctg aaactgcaaa aggcgttcca aatcccaact cataaaaatc gtatatatta
    34021 tcaaattgac tttgactatc aatcttatta accactaaga ttactggttt ttttgtcttt
    34081 ctaagcaatt gtgcaatttc tttatcagca gctgttattc cagctttacc atcaactata
    34141 aaaagtatta catgtgacat gtccattgca agcatggctt gatttctcat ttgagataat
    34201 attatatctt cgctatcagg ttcaattcct cctgtatcca ctaatgtaaa atatttatct
    34261 aaccattcta cttcagcaaa tattctatct cttgtaactc caggtgtatt ttcaactatt
    34321 gatatccttt ttcctgcaaa tttattaaat attgtagact taccaacgtt tggtctccca
    34381 actacagcta caactggcct acttatactc attttatttc tccttccatc ttttgttttc
    34441 tattttaaaa ttttatccac aaaatctttt ccttcattca aacaagggat aatttttatt
    34501 ctcataagtt cttctaattg atttaattca atattatcta agaaaatttc ttcatctgct
    34561 tttagcatac ttcttgttat ataaagagct tctcctaatt ctttatcttc aagttgttct
    34621 tttaaatcct tagctgttaa aagacctgat acagttattg tctctccaaa aaacttgttt
    34681 ttgatttcat atacatttac ttgaagattt ttaaacttgt ccatcatagc atctgccata
    34741 ctctgtataa attcatatgc agaatgacca gtagctattg atactttctt ctctcttttt
    34801 agaatcttct caggcaatat atttagatac tcttcaatct ctgtttttaa cttacgtatc
    34861 atacctacac catcttcaaa ctgtaaaaaa ccttcatatt cttcatatcc aggcaattca
    34921 ctattagata gtatataaaa ttcatctgat aaaaatgcaa atcgagtacc taatttttca
    34981 agatatttct gttgtatttg atgtatttgc tctatagttt tacttgcgct cttatcatta
    35041 aatatattta attctactag attttctcta tgctttgtaa tcccaactgg aactatcgca
    35101 acactgttta catacggata aagttgagct agttctttta ttgttctatc caattccttt
    35161 ccatcattta tacctggaca taaaacaatt tgacagttca tttctatatg agtatctgcc
    35221 aatctcttca ttataccata taattttcct gcaaatttat tgcttatcat tttttgtctt
    35281 aactctggat tagttgtatg cacagatata tttataggac ttattctata ttttataata
    35341 ttatttatat cttcttcact catatttgta agtgtgacaa aatttccttg taaaaaagat
    35401 aatctcgaat catcatcttt aaaataaaga gtttctctca taccttctgg caattggtct
    35461 ataaaacaaa acatacactt atttctacag cttttagctt ggtcaattat cggatttgta
    35521 aattcaacac ccaaatcttc atcatagtct ttttctatct cgtatatgta gacttcgcca
    35581 tctttttttt gtatttctac atctaaatat tcatcactta gtaagaatct atactctatt
    35641 atatcatgta ttggctgttc attcacagat ataagtaaat ctcctacctc tatacctatt
    35701 tcttctgcaa tactatcttt ataaacctta cttataatat tatttacttt ttttacattt
    35761 acttccaata ttttcaccac tcttttgtat tcatcaatgc ttattataat atattttaat
    35821 atgcaattta tttatttatt atattttatg atagcatttt taagcatttc atgtcataat
    35881 aacacatttt aattctaata gtcaatataa gtaaatagct ataaaataga ttagaacaaa
    35941 taatattcaa atttaagttt cttaaaaatt tgaatattat ttgttcttaa aaaaatttta
    36001 taaatttaat gttttactat gattaacgtc ccatttgtca tatcatgaac cattccacct
    36061 acacactttg acatcaacaa tgccttattt tgtaagtctt tctcatcatt tgcataaaat
    36121 attggacaac ctccaccatt tttcatattc ttatcaagtg taactatagc tagggtatat
    36181 tcatttaaac ctatatccat tcccatctta tgcacttcct ttctttccta ttttataatt
    36241 ttttagtgat aagttttttc ctttagaact tgaaagtatt gggcatgact ttacggcttc
    36301 cattactttt tccacattct tatctactgg taaataagca atcattatac tttcatcctc
    36361 tttattcctt ctaggtaatg gtacgaatga aggttctcca taatctccat ataaacctaa
    36421 ccttgaatat atattgtata ctattgcctg tctttgacct gagtcaaata atatccctgc
    36481 attagcataa tctttatttt taggaattat ttgtattcct acacctctat taatatatac
    36541 ttctctatca ctttttagac ctatatttgt tattcccttt aaatctccta ccttcaatat
    36601 agactcatct acaaaactaa tctcagcagg cattacatca gctatgtctc caatactttt
    36661 tctagtaaga agttttttta atataaaggc taacactaat ccacaaattg aacttattac
    36721 caaactcatt ccttcactta ttttcgtttc tgcaagtatt acataataca atcctattgt
    36781 taaaaaagat gtaactatac acatataatt tcttacttca taggttctag ctatctcttc
    36841 tatgaatgca gctcctctct ttacaagttg aacttcctct aagttttgca atgtatttct
    36901 tctatttgct ctcacttgtc taaattgctc tgctgctagg gataaaaaag ttatagatgt
    36961 ataagaacga tttataagag ctggaaccaa taatgctcct aatgaagaag cgacgaatgc
    37021 taatataagt tgagatagta aaacatttgg ttgcgttgga tactgttttt ggtctaaatt
    37081 caacattata attctagatg ttataccaat aataacagca acaaaaaata ctctatccat
    37141 taaatcactc ctaaaatatt taatttgaaa ttttacatgt aaatctacaa agtctttcta
    37201 gaaaaatcac tctgctttcc ttttgatgtt tctatgatag gtgtactttt cactacatct
    37261 atcatgacat ctatatcttt gagtattggc atatatggta taaccacagt acttttttct
    37321 aaattggtct tagatatagc aacaatatca acctcatcta catctctatc tatccccata
    37381 tgaataaata gattatgtat tatagcttgt ctttgcccta tatcatttac tattccaaat
    37441 gcacctaaat ctcttggtat aacttctatg gccagacatt catttctata cttttctctt
    37501 gtactttcta gacctatgtt agttattatt acaccattta ccattaaaat aggtccttca
    37561 aaacttattt ttgcaggaac tatatctgct atatctgcta tactgttcct tcttaaaaat
    37621 cttctaaaaa tcaaaccaac aatagctcct gacacaatag ctaggattgt gcaataaaaa
    37681 aagctaaggc catactttct tgcaaaaacg atataaacta tcgaagatac cagtgcagaa
    37741 aaaagactta tataacttct agattcatac gtagatgcta tttcttcaac gtaagcgtct
    37801 ccttttggta ctaattcttc attatcgata ttctttagtg ttattctttc ttgttctgca
    37861 agaccttgaa actgttgtat tgctactgca aaaaatgtca aggctgcaaa ctccttatct
    37921 ataagtgcag gtaatgctat agcacctaac gaagctgaaa gcccagatat aattatctgt
    37981 tctaaataat cttgtggtct tgatgggtat tgtttgtctg taactcttaa aactaatcct
    38041 ctacataata ttcctacaac taatgcaact ataaaagagt gtctaaataa atttgcattc
    38101 aataaacttt cttccatttt ctcagctcct tctcttatat agtttgtgca aaaaacaaaa
    38161 aaaattccct tctatttaag gaaatttttt tgtaatattg taactataaa ttcgctacca
    38221 atgccaagtt cactttttac ttttatacat ccatttagtg atttgactat atgctttgtt
    38281 atagccaatc ctaaacccgt tcctcctaca tccctacttc ttgctttatc taccctataa
    38341 aatcgttcaa atatgcgttc tacatcttct tttggtatcc ctacaccatt gtctataact
    38401 ttaattacga ttttttcttc atcttttaac actacaactt gtacaatccc attatcttgg
    38461 gtatacttta tagcattatc aactaggttt aagaacactt gctttatata gtctttattg
    38521 gatagtatac ttattgattt atcatcacat ttatataaaa cttctatatt tttttcacta
    38581 gctgaatgtt gagttatttc atatacctct ttaaatacat catatactac aacattttcc
    38641 ataagaagag tatctttatt ttctacaaat gataacagca atatatcatc aatcaacctt
    38701 tttaatctat ctgattcgct ttctattatt tctaagaatc tatttctagt attcacatct
    38761 atattttcat ttgactttag tgtttcaaca aacccactta tagatgtaag tggtgtttta
    38821 agttcatgac ttacatttgc aacaaaatca cttctcatat tttcaagttt aactttttta
    38881 gtaatatctt ctatatttac tatcgaacct attattacgt tgttagtatt ctgaagataa
    38941 actgggtcta cttttatctt atatacgata tcatctttag tagtaatatt agcagtttca
    39001 ttatctttag aaccaataaa ttgaagtatt tgttttaata tttcttcttc ttttattaca
    39061 acattaatat tatgaccttc aactaattga tttggttcac tctttatcat ttcttttgct
    39121 tcatcattta tcagaagtat atttccattt acatctatag ctaaaattcc atgagatata
    39181 ctctttaata tagaccttag ctgtaaatgt ttatactgta cttcttctaa ggttttatcc
    39241 atattcttta tcatatgatt aaaatttcta gctaattcgc caagttctcc tttggctgat
    39301 atgttaagcc tagcatgata ttcattatta cttacttttt ttgagacgta tataaactct
    39361 tttaaatatt tccttaatgt tattgtgtat cttacagcta atataacaat ggctatggac
    39421 aacataacaa taaaaaaata tatactattt aaatcttcca caagataaca ctcctaaaat
    39481 ataacctttt taatctattt tgtatcctac acctcttata gtctctatat atttttccga
    39541 tttatcttca tcttctattt tttttcttaa atatcttata tgaacatcta ctgttctagt
    39601 ttctccatag tattcatacc cccatatttt atccaaaaga taatttcttg aaagtacttt
    39661 tcctttattt tgaattaata attttaacaa ttcaaattcc ttaagagtta actctatctt
    39721 ttcagagcct ttggtaactt catgttttga taaatctagt tttaaattac ctgtagtaag
    39781 tatattgttt tcttcaccta agctagtcaa attatatctc cttaaaacag aactaatcct
    39841 agctaacaac tcttttatac taaatggctt agttatatag tcatcagcac ctatttcaag
    39901 cccttcaacc ttgtcatttt ccatattttt agcagtaagc attataacag gaatattttt
    39961 taagtcctta tcacttctta tttttctcaa aacttctatt ccacttatat ttggtaacat
    40021 ccaatctaaa agtattaaat ctggtttaat ttccttagcc tttataaatc cgtcaaatcc
    40081 atcatatgaa taactaactt cgtaatttga cacctccaaa ttgaatttta atagctcaac
    40141 tatatgcatt tcatcgtcta taacaagcac tttagtattc attaaaaagc tcctctctat
    40201 tttatctgta gtaccgttcc tattcgttct gatgccttat tatgttttct ataagagtgg
    40261 aatttatctg ctctacaact agtgcataaa tttaaattta ttatattttc ttttttaact
    40321 ccactacatc taagcatata ctcattaatt ttccataaat ctaaatagta acttccctct
    40381 tttattatat agaacttttc atcattattt gtaagaattg tgttaaattt ttctactaaa
    40441 tcttcagaca cttcataaca acatggtcca attgatggcc caattataca tactaaatct
    40501 tcaggaactg ttttatagca ttcagacatt aattttattg ttttatgacc tatattacta
    40561 aaagtccctc tccaacctgc atgagccagt cctatggctt tatttttagc atctataatt
    40621 gatataggta cacagtctgc tgtaaacagt aaaagtggta ctttttccaa gtttgttata
    40681 agtgcatctc catctcttct tttccctata gtatctttat tgactatatt aactatatct
    40741 gaatgtattt gagaattact agttagattt tcaaatgtca aatcacattc tttacatact
    40801 tttaacatat cttctctatt ttttgcatct atattcttac atgttataac tagatttaca
    40861 gaatttaatt tttcatcaag ttcttcacaa ttaccactta aattaacata ctctttaata
    40921 tcttgtacat tttttatatt tatataatct ttcatcattt gtctcctttt tctatcagta
    40981 tacttttaag ttcatttaca aaagtattta tatctttaaa ttgtctatac acagaagcaa
    41041 atcttacata ggcaacctca tctaactctt tcaatttatc cattaccatc tcaccgattt
    41101 ttttggtttc aatttcttct ataaaacatt tatttatttc attttcaata tgtacaacaa
    41161 tactttcaat ctcgtcaata gaaacaggtc ttttttcaca tgcttttagc aatccatatt
    41221 ttatcttttc tctatcaaaa tattctctac tattatcctt tttaatgacc attaaaggag
    41281 ttgtttctat tttctcatac gtagtaaacc tctttttaca tgattcacac tcacgtcttc
    41341 ttctgataga ttttaaatct gtatgtctag aatctattac ctttgattct ttataattac
    41401 aataaggaca ttgcatctat attcctcctt tgtttaacta tatctcaaac tcatctaagc
    41461 ttaattctga acctatattt actattattg tatcacaacc tattttaagt atatcattcc
    41521 aaaatataac ttcttcatcc cctcctcttg aaaaaaaact tctacttcca tctccaaaaa
    41581 tggtaaatga gactacctta ccttcgtgaa tatccatgtc tatgtctatt ataaacccca
    41641 tcctttttcc attttttaca tttataattt ctttttccat tatatcagaa actctaatca
    41701 tattgtactc accctttctt taaaaataaa tatgtatcga agtaaaaaaa aatgacctat
    41761 ataggtcatt taaattaaaa taatgtttac agtccatgga ttacttatac atattttctc
    41821 atattcttta aagcattttt ttcaattctt gatacttgtg cttgagatat accgatttca
    41881 tcagcaactt ctatctgagt tcttcctttg taaaacctta aatctaatac caacttttct
    41941 ctactattta atttcttaat agcttcttta agtgatattt cttgcaacca attttcatca
    42001 gtatcttttt tatcttgaac ctgatccata acgaatattg catctccatt gtcttgatat
    42061 actgggtcaa acagagatat tgggtcttgt atggcatcaa gtgccattac aactgattct
    42121 acttctaatt ctaattcctt tgctatttct gatactgtag gttctttaga atttgttcta
    42181 attaatcttt ctctaacttg tagtgcctta tatgctatat cttttaatga cctacttact
    42241 ctaattgggt tattgtctct tagatacctt ctaatttctc ctataatcat aggaacagca
    42301 taagttgaaa accttacatt ttggcttaaa tcaaagttat ctatcgcttt tataagacca
    42361 atacaaccta tttgaaataa atcgtctata ttttctcctc tgttgttaaa cttttttatt
    42421 acactcaaga ctaatcttaa attccctctt acaaactgtt gtctggcttc ttcatcacca
    42481 ttttttattt gtaataaaag ttccttcatt tgcttatttt taagaactgg aagttctgat
    42541 gtattaacac cacatatttc aaccttatta acttgcatat attttcagtc ctctctcaaa
    42601 agtattcatc tattgaaatt atttacattt ccaatttttt tatacttttt aagaagaatt
    42661 aatttagcat tatacaaatt ttttcatttc tttttgcaac cttgagatta ttttcttttc
    42721 aagtctagat atgtaggact gtgatattcc aagcattcca gcaacttctt tttgtgtttt
    42781 ttcaatacct ttatcaataa gaccaaatct taattccata atttgctttt ctctgtcact
    42841 taatctgtca agtgccataa ccaacaaatc tctatctatt tcttcttcaa ttattttgta
    42901 tatttcatca ttttctgtac ccaatacatc agataataaa agttcgtttc catctaaatc
    42961 tatatttaaa ggttcatcaa atgatacttc tgttttcttt ttattatttt ttcttaagta
    43021 cattaatatt tcattttcta tacatctcga agcataagtt gccaatttta tatttttatt
    43081 cagtttaaaa gtattaactg cttttatcaa acctatagtt cctattgaaa tcaaatcttc
    43141 tacatctata cctgtatttt caaattttct cgatatgtag actactaatc taagatttct
    43201 ttctattaaa attgacttta cactttcatc tgtttctagc ttttgtaaaa gctccatttc
    43261 ttcttctggt ttcaatggag gaggaagtat atttgcccct cccatatagt atattccctt
    43321 tggctttatt atttttaatt taatacctaa catagtaata aagcttatta ttctttcttt
    43381 caatcgtaac attccttgtc ccccttaaat tttcacctaa aatccaggca atatatttgg
    43441 attcattatt gctccatatt ctctatcatt aaaatttgaa ataccaagta ttatatttcc
    43501 tatcttttgc tcatctactt ctatatagtc agcttttaag cctattatta tgcttgtctt
    43561 attacttcca gcatgtttat aaggtattat tctaactcta cctgaagttt tatcatctaa
    43621 acttcctata atttcttgtg ctttcttcat atctatatct tcataattaa tatttaatag
    43681 tttttctgga ataaatcctt ctaacacact agacttaact attattacat cactttgact
    43741 tattgggtct tttaacaaat taccactatc tactaaagcc ttacagcaaa aacttttttc
    43801 tagtaagttt atatttatag tctttgtaag ctccttaatg tacttaagca ttttcaaatc
    43861 tttataaatg tattttaata attcacaact cacataagta catgcaatta agaaagatat
    43921 ttttaagtga cttattcctg taaaataaat tataaaataa gtgcttccag aaataaaaat
    43981 gtttactaga taaaaaacta acgctacatg aacataatct tttttgctct tacttctaaa
    44041 tgaaattaaa gttattatac tcatgattat tattttaaat ggtacagtaa atagtatatt
    44101 cattgatgga tacaaataag caacagaata ggcacctcct aaactagccc ccaataactt
    44161 atttttttta ggattatatc ttttagtaag aatagaagta caacttataa taatataatt
    44221 tattactagg ttttctataa catagtactc aatatacacc atgtatcccc ccttaaaacc
    44281 tttaaacata ttataagata gtatgtacaa aattttatgt cacttttgat ggtcgaatcc
    44341 aaaacaaatt ctatttaaaa agaacaatga tatatgtctt atactttatg tcgtcaaaag
    44401 atattttttt aatgccaaac aaatagactt ttttgtagaa tccaatatat ctaggtagaa
    44461 gttattcgct ctacttttgg tatatttaca aaaaaagact acataattta ataatatatc
    44521 aagtaaatct tttacttata taaaatcaaa ttatatagtc tgtaaattca aatataaatt
    44581 attgtgctag taatccattt gcatattttg cagattcatt tagtgcttgt tctggagtta
    44641 tgtctccagc tatcatcatt tgaagttgtt tccataaata ttcatatatc tctactccat
    44701 gaggtccaac tgtcaatggt ctatacatat gtttatctct tgtcaccatt tcttcaaatc
    44761 ttgggtctcc ttggtatttt tcacctttag caactggagc tctaggtatt tctttgtgga
    44821 aagcttccat tgattctttg cttagcatat actcaagaag tttaaatcca agttctttat
    44881 ttttacatgc tgacattaat gttaaatcat ctactgaagc aaaacttcca actgtcttat
    44941 cttctaatga tgttacatat ccccagttta aatccgggaa tgatttatca aatgtacttg
    45001 tagcagcaga ggatagcatt atagtaaatg cagcttttcc tggtccaaat acactttcaa
    45061 tcatttcatt actatctttt gataaagcat cttctggaat atactttttc atatcattta
    45121 taaagtttgc agctttcaag ccttctgcat tattaaattt aactgatttt aaatcatcat
    45181 tatatatatc tccaccagct tgccataaat acggatacca gttccagttt aagcttccaa
    45241 atactttaga accccaacct tgtgcaagac cccactggtc gatttttcca tctccatcag
    45301 tatcttttgt tgctttttca cagattcttt taaaatcatc ccatgttttt ggaggttttt
    45361 ctcctaattt ttctagtata tctttattgt agtacaatac gcctggatta gcagcttcta
    45421 taggtaaacc ataaatacca cccatcattt ttgcatcatc taagtataga taattatctg
    45481 aagttcctga tttttctaaa taaggtgtta aatcttctac cgcacccatt tctataaatt
    45541 gaggaaacat ctctgcatac atgtatccta tatctggacc ttcacctgca cttattgctg
    45601 ttgcatattt ttctgcgtag ttatcccatg gtactatctg aaattcaatt tcacagttat
    45661 tttctttttc aaatttttca aatatcggct tccatgcatc tgcatcatgg tctgttaatg
    45721 gtgcagacca tacaactaat ttttctttac cctctttgcc tttagaatct tctttttttg
    45781 aacatcctgc aagaattgat actgatagaa tccctaccat aactaaagaa agaacctttt
    45841 ttagtttaat catgcttaat cccctttcag actttaattt gtctttttcc tcaaatgttt
    45901 acatttaatt cagatttaat attaacaaat aagattactc ttgtctaatc ataaaaaact
    45961 atactaactc ctataactat attttttttc tatacctatt agatttaatt catactaaaa
    46021 acttactttt taaattttat caatatttaa aaattttttt aagtctagcc acaaactaac
    46081 tatctaaatt gagcaaaata aaaagaagtc tattgacttc tttataagct tacatattat
    46141 cttcttcttc ttaggaatgt aggtatctcc atgctctcat catcatcttc ttcaattata
    46201 cttgcctttt taggaggctc tattttttcc tcagcaatta cttcttcttc aatttctttt
    46261 acagcttgtt ttactgttgt atttaatgaa gaacgtatgc ttgatttagg tttagtatct
    46321 aaatctaagg caccattttg taatccttca aatcctgtcg cgattactgt aatcattatt
    46381 tcatcaccta aatcttcttt tatagaagct ccaaatataa catttgcttc tgggtcacag
    46441 gattccataa ctaaagttga tgcctcatta acttcaaata atcctaagtt aggaccacct
    46501 gtaacattaa gaagtactcc tttagctcct tgtattgatg tttctagaag tggagattga
    46561 atagcttgtc ttgcagcatc aattgctcta gtttcaccac tagcactacc tatacccata
    46621 tgagcaagtc ccttgtcttt cattatagta gtaacatctg caaagtccaa gtttattaac
    46681 ccttcaactg ctataaggtc tgaaattgat tgtatacctt gttttaacac atcatctgca
    46741 actgcaaaag catctaacat tgatgtattt ttttgtacta tctgtaaaag tctatcattt
    46801 ggtatcgtta taagagtatc tacttttgat ttaagttctg ctattccacc ttcagcgttc
    46861 ttcattctta tcttaccttc aaatgcaaaa ggtttggtaa ctacacctac tgtaagtatc
    46921 cccatttctt ttgccaagcc tgcaaccact ggagcagctc ctgtaccagt accaccgccc
    46981 attccggctg ttacaaagac catatcagct ccttgaagta actttactat ttcatcttta
    47041 ctctcctcag cagctctttt ccctacttct ggatttgctc ctgctccaag tcctctagtt
    47101 aatttttctc ctatttgaac tttatattca gcttttgatg tatataaagc ttgtttatct
    47161 gtatttactg atataaattc aacgcctttt agttgagctt ctaccattct attgacagca
    47221 ttgtttccac cgccacctac acctattact ttaatttgtg cacattcttc taattctacg
    47281 tcaaagttta gcatcataaa cccccttctc tcatgattca aagttatcgt atgtattaat
    47341 tatatcattt tcttctttta ttttgttaac ctttaagtaa catattccac aaaaacgtaa
    47401 attttccttt ttaaatttct tacttatatt gtcaaatatt actctttaag tataaaataa
    47461 tttacgtata tattaaatgc tctttaattt ttacgttttt tgttcataat attactaata
    47521 atatatcgtc taattataga taagttatta aacaatctca taccaaaaac taatacagca
    47581 acatagtaaa gagaaactcc taacttttct cctatataag tcaataatat agccaatata
    47641 gcattaccta tgaaaccagt aataaaaatt acattatcat agttatcttc aaaattggat
    47701 tttatcgctc caaaaataga atccattatt gcaagaatag ctactgacat atatatggaa
    47761 taatccatag aatatgtaaa tggaatatag taacctacta ctacaccaaa tgctaatcct
    47821 cctaaaaccc ataacataaa tcttcacctc tttattttac tttgaaacac aactacatta
    47881 caatcctttt tattaatttt ttttactttt tctttatttt tttgtatttt tcgttttatt
    47941 ttgcaaataa attcacttta tttccattat tttcctgaac ttttatatta attccatata
    48001 tatccttaag agatttagca tatgattctg gagagtttat agctgcactc aataaatcta
    48061 tatctcctat agcttttatt ataaatggtt gtccatatgt agtatcattt actgtaatag
    48121 tagctcctga acattttatc ttacttgttg ctagtactct ttctccattt atagaaattg
    48181 ctcttgctcc agcctttttt aaatcattta aaaccctcaa aatatctata tcatgtataa
    48241 tcaaatcgtt tggattctgt ccgtctttta actctctctc actatccctc atagtaatag
    48301 ttatgcctgg ccctgtaaca gttgaataac cacttaattc tttaacttct tcaagctctt
    48361 tttgcataag tgtttggata gattcatttc cattcttttt tgcttcttta tattcattca
    48421 aagttttttt gttcttttta agagtttctt ttaagttttt tatttctttt tttgtatttt
    48481 ctacctcact ttcaatactt tcagtttgac ctaatgttat gtatactcta tttgggtcta
    48541 gtgattttat ataagttgat atgaaaacgc ctaatatgaa tgctcctaat ataactattt
    48601 tctttttcat actattattt cccctctgct ttgtttatat cactatgacc atttatttct
    48661 atattgtctt ctttggtcac ttttactttg gcattataat atgtttctat ttcccagaca
    48721 ataccatact ttatattaag tgccgaagcc aatgtatcag aatcaccaat tgcttttatt
    48781 ataattggtt cttttatgac agtgtcattc atataaagct tgtcttcttt taaatacata
    48841 tatgtattag aaactattct ctggtcgttt atagatatgg cacttgcttg tgctgaattt
    48901 aatttattta tcattgataa taataaatca taattatata gtatactatc atttttatca
    48961 gagtttccta agtcttttgt agaatttatc tcaattttta tgcctgttcc ttcaacatct
    49021 gtatatccag ctaatgtttc atatttttct atttctgact taagtatgtc ttgttctcct
    49081 tcattgtttt tgcctctata aatctctata tctttcttca cactattaac ttctgattgt
    49141 agattctctt tttctttttt taaagattta agttcttctg taagttgctc tcctctttta
    49201 aaagttgtca tccctctatt ttctatatta ataattttaa gttgtaaact aacaagaaca
    49261 cccaatacaa tacttcctat gattatactt ttatttataa atcttttttt caatatatca
    49321 cttccttaca attgtctatc cttctggact atacactgcc aactttccat agttaagatt
    49381 tatagtccct ccattagtat ttttattttg caggtcaatc agaattttac ttaccctaga
    49441 tatattataa tctaagttat catcattaga aagtaagatt tttatattac ttcttgtaag
    49501 catttctata ttgctttctt tttttaagtt tacataattt atttttctat aaattccttc
    49561 ttcttttaaa taatttaaag ttttaaatac attctcctta gttttataat ttttaaattt
    49621 tatagattta ttatcatcaa tgctataatc tacatctact atcaagtctt ttttactttc
    49681 attagaacct cttagttctt ccaataaatt tcctttttta tctatataac aataattatc
    49741 ttcatctttt aatactgcaa atatttcttt ttcttttaaa cttataatta tcttattggg
    49801 aagttttctt tttatttcca cattttctat atatggattt tttataagtt tatttttcat
    49861 atctttaaaa ttgtatgcaa aaatattttc atttagattt acatttagtt ctttcattat
    49921 atttgatttg gtcaccctct tatttccaat tacatctatt ttctttacat caaataaatc
    49981 actttttaca attatacata tacaaaaaga taacataagt ataaaaacta aaactatcat
    50041 gacattattc gtatttaact ttcttctttt tttcaaatat aatcaacccc tttggttaat
    50101 aaatacacct ttagagcttg tttttcctac aaaaaaatta taatatttaa agtcaaattt
    50161 ttgcatttta ttacataaca tccaaataag gtattaaatt ttataaataa atcaatattt
    50221 catcaaaata aacatagcat actacatact atttatatat ttaaatctgt atacatacaa
    50281 ataaacccct aatttataat aatttagaaa atctaatata ttataaatta ggggtaaata
    50341 tttacttatc ttttctttat tcctattacc ttagcttgac cttctatact tggagtcgtt
    50401 tcttttttta tttcttttac ttccttaata actttttctt tttttgtttt tttagaagtt
    50461 gacttttgtg ttgaattgta tactttcatt atctcatcat atataaggtc tatggcttca
    50521 ggcttaccta tagttttact tgcatttgcc atatcaacca aaagttctct atctcctaaa
    50581 agtttaaata ctgctgtatt taggctctct ggagttagat ttttttctaa aatagcaatt
    50641 cctgcccctt gtttttctat actcttggca ttatactctt gatgattttc agcagtataa
    50701 gctttaggta ttattataga tggctttcca agagccgtta tctcagctaa tgaaattgct
    50761 cctgcgctac ctataaccaa atcacttgct gcaagtgcat ttgccatatc ttctaagtaa
    50821 ggcacaactt tttggtatgg tttaagattt atatcgctaa tacttcccat aaattcatca
    50881 taatagcttt tgcctgtagc aaatataaaa gctatatctt catttaccat attctttatt
    50941 acaagtctca ttgcatcatt tatttttctt gaacctccac taccaccata gcaaagtacc
    51001 attctttttt cgtcacttat tgatagattc tttcttgcaa tattttttct tgataataaa
    51061 atttcttttc taactggatt tcctgtaaaa actaatttat cttctgctgc ctctggaaat
    51121 cttttatgcg aatcttcaaa acttgtaagt acctttgtaa ctgttttaga taaaatctta
    51181 ttagttacac caggaaaaga attttgctca tgtattatgg ctggtatttt ccccatagat
    51241 gcattaaata aaacaggtcc actaacatat ccaccagttc ctataactat atctggttta
    51301 aatttcttaa caatctttct tgattgctcc aaacctttaa aaagcttaaa aactcttttt
    51361 acattatcga aatctatttt tcgcttaaag ccttgaactg ttacagtctt taattcaaat
    51421 ccatacttag gaactatttc tgactctatt cccttttccg tcccaacaaa aattatctca
    51481 gcgtctggat gctcatctct tattttgttt gcaatagcta tagctggata cacgtgccct
    51541 ccagttccac cgcctgataa taaaactttc atcaaatcat catctcctgt taattaattt
    51601 tgacatgctt tgagatgttt aacactattc ctacagctcc cataaagatg gtgagtgaag
    51661 ttcctccata acttataaat ggtagtgcta cacctgtagc tggcattgat gatgtcgcaa
    51721 ctgctatatt taaagctgct tgtattccaa tttgtgcacc tatacctata acaaccatac
    51781 aagcaaatac attagaagtc ttcaaagcta ttcttacaca tctgtagact aaaactacaa
    51841 atagcataat aactattata caaccaatca atcctaactc ttctcctatt atagcaaata
    51901 taaagtcatt ttgtggctct ggtatataaa aatacttttg tttactcttt cctaagccta
    51961 gaccaaacaa tccacctgaa cctagtgcat atagaccttg tattacctga taccccttac
    52021 caagagggtc ttgaaaaggg tctaaaaatg atgtaacacg actaagtcta tagggttcag
    52081 caattactaa tgcagcaaat aaagcagccc cactccctat catagcaaat acaattttca
    52141 tatccattcc agcaacaaat atcattacaa aagtaactag aattacagta cctgctgttg
    52201 acaaatttgg ctgaagtatt atcaacgcaa aaaatatccc tggaactacg agaagtggta
    52261 caacaccttt tgtcaaagat tttattttat cataattttt ttcaattaat tttgcagtta
    52321 atattattgt agcaaacttt gcgatttctg caggttgaaa tgttaaagct cctattccca
    52381 accatctttt tgctccgttt gcttctatcc ctaaaggggt caaaactaac aataataata
    52441 ctactgctat agctccaatt gctgtagcat ttttcttcca aaaactataa tctattcttg
    52501 atgtaataat cataactata aatccaagta cagcatatat tacattcttt tttagaaaat
    52561 agtacgcatc attgtgttta aatgaagatt gtataaaact tgcactaaac accataacta
    52621 ttcctacaaa tactaaaagc atagtagtgt aaaacactac tccatcaaat tcagtcttca
    52681 tccttatgtc aatttgtttt ttcaaatttt ctttaggcat ccaactaatc tacctccatt
    52741 cttccattta agtaagttta gaggtaagag attattttaa attgtttaca ttatctttga
    52801 agtcttttcc tcttacttca aaactttcat acatatccca acttgcacaa gctggtgaaa
    52861 gaagcactat atctccactt tttgaaattt cataagaagt cttaactgct tcttccatat
    52921 cttttactat atgtatgtca ttaaatcctt tatttttagc acaattttct atatttgatg
    52981 cagtttctcc taataagacc aatgatttaa catatgactt tgcagtttca agaagttcat
    53041 caaaattact tcccttatcc atcccccctg ctataagtat tataggtcta tcataagact
    53101 gtatagcttt tatagtggaa tctggattag ttccctttga atcatttaca tatattacat
    53161 tgtctaaatt tcttacaaac tcttgtctgt gttccactcc tttaaatgtc ataagtacat
    53221 cctttataac ttctaaatca attttgcaga catatgctat tgctatagct gccatacaat
    53281 tttctaagtt atgacctcca ggtaaactta catcatcttt atttagaaat ttgattttat
    53341 catctatatc tattattatg tcattatttt ctaaatatac tcctccattt acttttttag
    53401 ttcttgaaaa gtaaattact ttggcattgc atttatcagc taaagatttt actatctcat
    53461 catcatagtt taatacacag aaatcctcaa cagtttggtt cataaatata tttgcctttg
    53521 cttctatgta tttttccata gtatggtgtc tatttaaatg gtcctctgta atatttaata
    53581 ttgcgcttac tttaggtcta aattcatcta tactctcaag ctgaaaactg cttagttcag
    53641 ttactaacac agactcttca cttgaagttt ctatagtatc tattacagga tttcctatat
    53701 taccaactac atatgtatct cgttttgctc ttgaaaaaat ttctcctacc aaactagttg
    53761 tagttgtctt tccatttgta cctgtaatcc ctataaaaat tggattattc gatagtttaa
    53821 aagctaattc tacctcacca attatatact tgcctgaatt ttttaatttc aatatgaatg
    53881 gtaggtctag tggtacacct ggagacacta caaccatatc tatatcatct acatcttctg
    53941 ggtgatgtcc taatatgtat tttatgtcat ttatagattt caattcatca agtatatttc
    54001 tcaatttatt ttcatctttt atatcattta cgattacact tgcacccaat ttatctaaat
    54061 gtttaattgt agatatacca gtttttgcaa gtcctactaa taaaactttt tttcctttta
    54121 agtccatttt tcattccccc tagccctaaa atactgctat tatacttatc caagctaaaa
    54181 caactgttat aatccaaaaa ataaatacaa ctcttgtttc tggccaacca cactgttcaa
    54241 agtggtggtg tattggagcc atcttaaaga atctctttct tgttgcctta aaatatccaa
    54301 cttgaatcaa aactgataga gcctccgcaa aataaattcc tccaattata ggtattataa
    54361 gcactgagtt agttagaact gaaaatgcta caactgcacc tcctaatgcc attgaacctg
    54421 tgtcgcccat aaacactcta gccggatatg aattaaatcc taagaaacct aaacatgctc
    54481 caacagttgc tgctgctaaa actgcgactt ctgtatttcc agcaatagaa cttgcaaata
    54541 gcataaagaa tacagaaact attaatgtta ctcctgatgc taatccatct aatccatcag
    54601 tcaagtttac agcatttact attgctacga ttataaacat cattattggt atatataata
    54661 ttccaacatt tatcacaaaa tctgtaaatg gtatcataag ttgtgaagca cttgatgatg
    54721 atgtatactg ataaaaagca acataaaaag ataatgcaac ttgaaggatt attttttgat
    54781 atgcttttag tccaagtgat ctttttagct ttatttttat aaaatcatct aaaaagccaa
    54841 taaaaccaaa acctgcaata catataagac ctactgccat atcatgacta acttttactc
    54901 ttgtaagtcc agttattaga attgcaacaa tcattataat tccacccata gtaggtgttc
    54961 cgtttttagc tagatgtgtt tggggtccat catctctaac tgtctgacca aatttaaatt
    55021 ttctaagcat tggtataaat attggtccta ttataattac tattaaaaac gcaatcaatg
    55081 cggtgtacgt aagctctgtt attcctaaca tcataaaact cctctccctt gtcaattaac
    55141 tcattagttt aagcttattt atttagatat tcgactattt tttctaatct catgcctctt
    55201 gagcctttta ctaaaatagt gtctcctgtt tttactaatt catttaactt gttaaacaca
    55261 tcttctctat tctcaaagtg atatatattg gctgaattga atcctaattg ttttgcttct
    55321 tctccaataa acactgaatt ttcacctata gttattataa tatcagtatt attcatagat
    55381 gattttccaa ctaatctatg accatactct gaaatttcac ccatttctag tatatctcca
    55441 agtatcgcta cccttctacc tttatatctt ccaagtatct ttaaagcagc atccatagaa
    55501 tctggactag cattatatga atcattaatt attgttaatt tttcattttt tattatgtct
    55561 aatctcattt ttgtcccttt aaaatttttt aaaccttttt ttatataatc taaagaaata
    55621 tttagacaca aaccaactaa tatagcagac attgcattat atatattatg ttctcctatt
    55681 gttggtataa atatttcctc ttttttccca tttattacac atataaatgt taaactatcc
    55741 tcttccatag tataactttc acaataaaca tcattgtttt tattaaagcc aaatgttttt
    55801 aacttatata catgttcttt ttcttttaat gtagataaaa acttatcatc tccatttaca
    55861 attaaagtat ttgtttcatc aaagtttgaa gtaatctcca tctttgcttt caaaataccc
    55921 tcttgtgaac ctagtttttc tacatgtgat aatcctatat tcgatatgac tgcaatttta
    55981 ggatttacta tatccactaa atattttatt tcattgaatc cagacatacc catctctatt
    56041 acagcacact catgttcttt atttagatta aataaagtca atggaactcc aaaatgatta
    56101 tttaagtttt tttcattttt tagtatattt aactttgcag atatggcaga gtaaatcata
    56161 tctctagtag tagtttttcc cacactacct gtaacaccta taaatggaat atcaaatttt
    56221 tctttatagt attttgaaat atctcctaga gccaaagatg tatcttttac ctctattaaa
    56281 tttatatccg aactttctaa ttttattcca ttactttcat tttttataaa agttttacat
    56341 ccactatcat atgcagactt cataaatgta tgcccatcta aattttctcc aactatggct
    56401 acaaatgcat tttgggcatt tgcctccctg ctatctataa ctatatcact tacacagtca
    56461 ttataatctc catatattaa cttcccatta gttgcaagta ctaactcttt tattgttaag
    56521 cactccatta ttaaactcct cctttaaaac cttagctata ttctcttagc aacaaaaggc
    56581 aatgtatacc gttatatata cattgcctac gataactctt aactttataa ttatatacta
    56641 tatttctgtt tttttgaaga tgtttatggg tatatgttaa ttatctgtta ctttttagtt
    56701 ttcaaaatat agggttatac ttgagtcttc attaactttt actccaggtt ttgggaatat
    56761 atcctttacc tttgtatctt ctggaagttc tatatctgca tctaagtctg gttttaactt
    56821 cgcatcctcc aatgccttta cagcatctcc tatttttaga tttcttacat ctggcacttt
    56881 aacttgcttc ttttcatact cagctttttc ttcttcttta tatactggtt taactcccaa
    56941 atattttaaa gagtcattca ttatttcttt cactattggt cctgctgtag tactaccaaa
    57001 tgcacttact cctgttggtt cgtcaacaat agcaagaact actatttgcg ggtcatcaca
    57061 aggtgctatt ccaacaaatg aacatatata ttttcctgga gcatacttac catctataac
    57121 tttttgagct gtacctgttt taccaccaag tctataacct ggtatatatg ctatctttcc
    57181 tccaccttca gttacaactg attctgcaat ttctaacatt tttttagatg tttctttaga
    57241 tataacactt cttacttttt ttggttttac tgtttcagtt atatttcctt tattgtcagt
    57301 ataagatttt accactcttg gttgcattaa atctccacca ttagctattg atgatatagc
    57361 tgttataagt tgtattggag ttactgatat agattgacca aatgatattg tagccaattc
    57421 aactggtcct acattttttt cgttatacag tattccctta gcttctcctg gtaaatctat
    57481 acctgtctta tccataagac caaatgattc tatataatca tacatttttc caacacctaa
    57541 tctgcttccc aactcaacaa atactgggtt gcaagagttt tgtactgctt gtttaaattc
    57601 ttgtgttcca tgaggtctgt aatgtctcca acatttaatc tttcttcctc caacagttac
    57661 actacctgta catgtgaatt tttctccatc tttaattact ccttcttcaa gagcactgga
    57721 agatgtaata agcttaaatg tagaacctgg ttcatatgta tcacttactg ctggatttct
    57781 ccacatttga taatagcctt ttattttatc tttatcatta tatttttcaa gttcttcttg
    57841 ataatatgga tatattggcg ttcttgagtc attagggtca taatctggtt ttgatgctaa
    57901 agcaagtata tcacctgttt tagggttcat agctattgca gtaacctttt ttgcattatt
    57961 taactcataa gctttctgta ctgctttttc agtatagtgt tgaattactt catctataga
    58021 caacacaaga ccattacctt gtacaggctc ataatatttt tccattcctt gtggtatttc
    58081 tcttcctgaa gcatcagtac ttactataag ttttccaggc tttcctttta actttttatc
    58141 atattgcatt tctacaccag atatacctgt tgcatctgaa gaagtatgtc ctaacacata
    58201 tggtgcaaaa ttcccatatg ggtaatatct ttgattatct tctgccaccc atattccact
    58261 taatttagca tctcttattt gacttgcctt atcatcatct atccatcttt ttacttttac
    58321 aagagccata ttttttttgc ttattaaagc gtaaatatct ttataatctt catccaaaat
    58381 ctcagctacc ttttcggctg cttctttttt atcttctact tccacaggtt tacaccaaac
    58441 agtatactta gttacactta ctgctaactc tttcatattt ctatcatata tagttcctct
    58501 tttgggttct attggtatat ctcttgtttg ttgttctagt gcttttgtac tcaaccaatt
    58561 tcccttcata agttgtagat acccagtcct aataacaagg caaaaaaaca atgcacatgc
    58621 tagaataaga acgagtacca gccttttctt acttatcctc tttacttttc tcaaatctat
    58681 tccccctagt tatccacatc tatatacttt atttgtccat cttttggata gtccatattg
    58741 agcaattcct tagcctttag ctcaatttct tttattgatg ttttttcagt ttcttttgcc
    58801 tttagttcct ctaatactat ctcttttttt cttaaatctt tttgtaaata atagatatcg
    58861 tacttcattt ccgagatttt tgaataacca catagattca atattattac tgaaaaagtt
    58921 gcaatcagta aaatgcattt agctcctatt tttttcttat ttctcttttt ataattattc
    58981 ttttttttat ttttatattc atttagatta tgtattttat aatttttttt caaattctca
    59041 ccccgatagt atatagttta aattttcctc tatactatat ttgttattaa tcatatttct
    59101 tcctctaaaa tttcatcgct aaattaatac actattacac aatctaattg tatttttttc
    59161 tatacacaac aaaaacctat aaat
//
LOCUS       DAEPHU010000017        55245 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 01A10CD0081
            SAMN05941466-rid12468953.denovo.017, whole genome shotgun sequence.
ACCESSION   DAEPHU010000017 DAEPHU010000000
VERSION     DAEPHU010000017.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941466
            Sequence Read Archive: SRR6291087
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 55245)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 55245)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068158.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 22:43:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,892
            CDSs (total)                      :: 3,805
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 87
            rRNAs                             :: 8, 1, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 55
            CDSs (without protein)            :: 55
            Pseudo Genes (ambiguous residues) :: 0 of 55
            Pseudo Genes (frameshifted)       :: 21 of 55
            Pseudo Genes (incomplete)         :: 28 of 55
            Pseudo Genes (internal stop)      :: 16 of 55
            Pseudo Genes (multiple problems)  :: 8 of 55
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..55245
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941466-rid12468953.denovo.017"
                     /strain="01A10CD0081"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            146..1342
                     /locus_tag="KR231_001122"
     CDS             146..1342
                     /locus_tag="KR231_001122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetate kinase"
                     /protein_id="HBH0003526.1"
                     /translation="MKILVLNCGSSSLKYQLIDMNNEEVLCIGLVERIGIEGSILKHE
                     KAGRDDKYVVEQPMKDHKDAIALVLEAVAHPEFGAVKEMKEIDAVGHRVVHAGEKFAT
                     SVVITPEVEEALKECIDLAPLHNPANIMGIDACKAILPDVPMVGVFDTAFHQTMPKSS
                     YLYGLPHELYTKYGVRRYGFHGTSHNYVSQRAAEILGKDIKDLKIVTCHLGNGASIAA
                     VDGGKCVDTSMGFTPLEGLIMGTRCGDIDPAILPFLMRKEGLDADGLDKLMNKESGVY
                     GMTGISSDFRDIEDAAKNGDERAQATLEAYVKKVQKYIGAYAAEMNGLDVVVFTAGVG
                     ENGKAIRADIASNMEFLGMKLDKEANDVRGKETVISTADSKVKMLLIPTNEELMIARD
                     TLRLVK"
     gene            1435..1959
                     /locus_tag="KR231_001123"
     CDS             1435..1959
                     /locus_tag="KR231_001123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF177 domain-containing protein"
                     /protein_id="HBH0003527.1"
                     /translation="MKVSIEKINRKETDKIDLNFCEKIDTISYCDEIYKLVSPVNLKG
                     KVSKTNKGLYLDIDVNFTIVDNCSRCLKEVEIPLEYSIQGFLVKEEDYDEDEFEEFDP
                     FIFDGEEIDLIDIIEQTLDFNVPHKVLCSENCKGLCQVCGANLNEEECSCSEITNDEE
                     YIDPRFAKLKDLFN"
     gene            1984..2160
                     /gene="rpmF"
                     /locus_tag="KR231_001124"
     CDS             1984..2160
                     /gene="rpmF"
                     /locus_tag="KR231_001124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L32"
                     /protein_id="HBH0003528.1"
                     /translation="MAVPKRKTSKSNTKMRRAANSKMEATGFVSCPQCHEPKLPHRVC
                     PDCGYYKGKEVVSK"
     gene            2367..2924
                     /gene="fapR"
                     /locus_tag="KR231_001125"
     CDS             2367..2924
                     /gene="fapR"
                     /locus_tag="KR231_001125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription factor FapR"
                     /protein_id="HBH0003529.1"
                     /translation="MKKKSKAQRQKELIDMLKTDPFYTDEELSSLFDVSIQTIRLDRM
                     SLNIPELRERVKSIAETQSSKVKTLGVKEITGEIIDLSVGRLGISMLEVTQDMIYSKT
                     NTLKDTYIFSLADSLAMAIIDAPKVIMRVANVKSFKLIEQQDRLIAKAEVYRNIDKKH
                     YVKVVINNKAQEQIFRGKFIFEELD"
     gene            2935..3957
                     /gene="plsX"
                     /locus_tag="KR231_001126"
     CDS             2935..3957
                     /gene="plsX"
                     /locus_tag="KR231_001126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acyltransferase PlsX"
                     /protein_id="HBH0003530.1"
                     /translation="MKIVIDGMGGDNAPKSNVEGAVNAIKEYQVDLIITGDKDLLEKE
                     FSNYEFDRNKLEIVHTTEIIENEDKPVKAIRSKKDSSMVVALNLVKEGKADAIISAGN
                     TGALLAGGLFVVGRIKGIDRPCLCSAIPNVKRGMTLIADCGANADCKPKNLVEFAAMS
                     NIYSRKVLGLENPKVALANVGLEEGKGNDLVKRSYEEIKKLDLNFIGNVEAREVINAY
                     TDIIICDGFTGNILLKSAEGVALSVMSLIKETFMASTKSKIGALLIKDDLRKLKSFID
                     YSEYGGAPLLGLNGGVIKAHGSSDAKAIKNAINQGIKFSKGKVVEDINQFISKYNEEN
                     KNNEDE"
     gene            3983..4969
                     /locus_tag="KR231_001127"
     CDS             3983..4969
                     /locus_tag="KR231_001127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketoacyl-ACP synthase III"
                     /protein_id="HBH0003531.1"
                     /translation="MNTKAGILGVGSYLPEQSYDNFHFEKIMDTSDEWISTRTGIKER
                     RFAKESEATSDLASKAALKAIECAKLNVEDIELIILATITPDMSLPSTACIVQDAIGA
                     VNATAFDISAACSGFVYGVTIAKQFVETGCYKNVLVIGAETCSKFLNYDDRTTAVLFG
                     DGAGAAVIGPVNEGGILSTHMGSDGKGKDCLKVPAGGSRLKASKETVEANLHTIEMAG
                     SDVFKFAVRKMAETSLRALEKANLNTTDIDYLVPHQANIRIIQASSKRLELDMKKVYV
                     NIDKYGNMSAASIPVALDEAYREGKIKKGDNVVLVGFGGGLTWGASVVKWTL"
     gene            5078..6007
                     /gene="fabK"
                     /locus_tag="KR231_001128"
     CDS             5078..6007
                     /gene="fabK"
                     /locus_tag="KR231_001128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-[acyl-carrier-protein] reductase FabK"
                     /protein_id="HBH0003532.1"
                     /translation="MNKICKILNIKYPVIQGGMAWVATASLASAVSNAGGLGIIAAGN
                     APKEAIKKEIVECKKLTDKPFGVNVMLMSPFVDDIIDLIIEEKVQVITTGAGNPAKYM
                     DRLKEAGTKVIPVVPTIALAQRMEKLGATAVIAEGTEGGGHIGELTTMVLVPQVADAV
                     NIPVIAAGGIVDGRGIAASFALGASAVQVGTRFICSEECSVHSNYKNLVLKAKDRDAI
                     VTGRSTGHPVRTLKNKLSKEFLKMEQNGATPEELDKKGTGALRFATVDGDIEKGSFMA
                     GQSAAMVKEITPCKEIIEAMVNQAREIMPAIEL"
     gene            6023..6973
                     /gene="fabD"
                     /locus_tag="KR231_001129"
     CDS             6023..6973
                     /gene="fabD"
                     /locus_tag="KR231_001129"
                     /EC_number="2.3.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACP S-malonyltransferase"
                     /protein_id="HBH0003533.1"
                     /translation="MGKVALVFPGQGAQYVGMAKDLYENNTVAKSVIDEASDALNMDL
                     KNLMFNGNEEELSKTENTQPAMVTHSVAVLKAVQAQVDLKYSACLGLSLGEYSALVAA
                     DAIDFKDAVCLVKKRGKFMQDTVPTGVGAMAAILGLDRSILENVVKDIQGGIVEVANY
                     NSPGQIVISGENEKIEEAMVKCKEAGAKRAVKLNVSGPFHSSMLREAGVKLASELEKV
                     NITKPKVDVVANVNADYYKNEGKDLLIKQVSSSVLWEDSIERLLNDGYDTFIEMGPGK
                     TLKAFIKKIASNKKANVNIYNIDGIDSLNEFVQNYRNGEI"
     gene            6973..7722
                     /gene="fabG"
                     /locus_tag="KR231_001130"
     CDS             6973..7722
                     /gene="fabG"
                     /locus_tag="KR231_001130"
                     /EC_number="1.1.1.100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-[acyl-carrier-protein] reductase"
                     /protein_id="HBH0003534.1"
                     /translation="MINLTGQVAVVTGGSRGIGKEIAKKLASFGADVVINYTSKEDEA
                     LKTKNEIESMGVKCTSIKCDVSKFDEVNQMIDSVVSEFGKIDILVNNAGITKDGLLMR
                     MKEEDFDRVIDINLKGVFNCTKAVTKPMMKKKYGRIINMTSVVGIMGNAGQTNYCASK
                     AGVIGFTKASARELASRNININAVAPGFIETDMTKVLSDDVKESTLANIPKKSYGKPE
                     DVANAVAFLVSDMSSYITGQVINVDGGMVMQ"
     gene            7776..8000
                     /gene="acpP"
                     /locus_tag="KR231_001131"
     CDS             7776..8000
                     /gene="acpP"
                     /locus_tag="KR231_001131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HBH0003535.1"
                     /translation="MFNKVVEIIIEQLGVEDKEITMETSLMKDLEADSLDAVEIIMAL
                     EDEFGIEIPDTEAENFKSIGDIVKYIEANK"
     gene            8029..9267
                     /gene="fabF"
                     /locus_tag="KR231_001132"
     CDS             8029..9267
                     /gene="fabF"
                     /locus_tag="KR231_001132"
                     /EC_number="2.3.1.179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-ketoacyl-ACP synthase II"
                     /protein_id="HBH0003536.1"
                     /translation="MNKRVVITGLGCVTPLGTGKEEFWSNIKSGVSGIDKITNFDAST
                     YQTQIAGEVKNFHPEEYISKKELKRLDKFAQFAIVSAKLAVEDANLDLDKVDRERFGV
                     IIGSGIGGVEAIETQHKILLEKGNKRVSSLFVPMMIGNMAAGQVSIFLGAKGPNTNVC
                     TACASGTHSIGDAFKVIQRGDADIMVAGGSEAAVTGLAFAGFCNMKAMSTRNDDPKTA
                     SRPFDKDRDGFVMGEGAGIVILEDLEHALARGAKIYAEVVGYGLTADAYHMTTPAENG
                     EGAARSMNMALKEGNVPLEEVDYINAHGTSTYYNDLYETMAIKTVFGEKAYDLCVSST
                     KSMTGHLLGASGAIEAVVCAMSIEDSFVPPTINIQEVGEDLDLDYVPNQGKEKNIRYA
                     LSNSLGFGGHNATIVLKKYV"
     gene            9493..11211
                     /locus_tag="KR231_001133"
     CDS             9493..11211
                     /locus_tag="KR231_001133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diguanylate cyclase"
                     /protein_id="HBH0003537.1"
                     /translation="MNFRLPKKRLPKKIIFICIILISIILFIKHDQNGLKEREIINKG
                     KYMSESLVADKEYDEAKKVVKTSFESIPEKKYNKVYNEVWDMLKTISYVPDGTKIVID
                     SLEKMRESDVKLSDECRFNIEKRLASVYIMDNNYFKAVDLTVKSIKLAEKLGNNYEKA
                     RLDVDLASIFLKIGGYETGEKLIKDSFKIDIDEGEKNGMVRLYAIINLAEIYVEEGEY
                     DKAIEISSRIKDYKKFVNTDNYNDFDIMASIMQSNAYVGKNNIQKAKTFLEKADYLIK
                     SDRTVYILDKDMYYYMAMGNLEYKSENYNSAIDNYKKSLEISTKRKLTQEKIKNLNKI
                     LNIYEKQGNIESLNEYQKMLINEYKENKSIRDSETSFYIIDKVSNESKLFEKTKKEIK
                     YYKILFTVILIAILGSTFLYNRLKYFKAQNLHDGLTNVYNRKSFDIMYEKYREKDDNF
                     ALVMIDIDNFKLINDNYGHKFGDTVIKGITNTICVMLEQDDKVFRYGGEEFSVLIRNK
                     SGDEVADIIDSIRVAIANKKWNDDVTVTISAGVAHVSDSKDVLEEADKNLYKAKQLGR
                     NKVVYK"
     gene            11242..13242
                     /locus_tag="KR231_001134"
     CDS             11242..13242
                     /locus_tag="KR231_001134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HBH0003538.1"
                     /translation="MKQSIAIVTDKITKLSSFLEENIRLVLGNYIDINHYYLEVLKEN
                     DKIQGDFVLVMNDDRLNSMRKHLVQDSKIIVIRRTLKENEIYGLFSIPNGTEVLVVND
                     TKETTLETISLFYKIGVKNLKFTPYIEGKIYKNIDIAITPGVKGKVPSYINKVIDLGN
                     RYIDISTFIEIINGLRIDVKEIRKNLMAYSESLISLDNGVKDNYRQLFLKIEEQDVIL
                     NLSKDGIIFTSADGIINTFNKEALKILGINENPQGKNIEDIISEDLNILLEDKEIIDE
                     VVFTNKKYINVNKKSIFSMGNKAGIYYNLQEITYIKKLEQNLTNKLREQGQIARYTFK
                     DIKTKNKNMVKCVELAKKISKSELSVLIIGESGTGKELLSQSIHNASNRSNQPFIAVN
                     CAAVPDSLLESQLFGYEKGSFTGALREGKKGLFELANNGTIFLDEIGDMPPLLQTKLL
                     RVLQEKQVMPIGSHNVINIDVRVIAATNKNLLKMIREGKFREDLYYRLNVLPIDVPSL
                     RNRKEDIITLMNFFLKNNIRLSPEVITILEKYNWPGNIRELQNVASYVSLMCDSMVFR
                     DDLPPYIRVECANNYEDGFGYTRKEFEEILRILYERRESSSGIGRGFIIEKLIQEGIE
                     ISESKVRKVLSYLSECGYISSKSGRGGSQITSEGIKLYNNIN"
     gene            13593..13838
                     /locus_tag="KR231_001135"
     CDS             13593..13838
                     /locus_tag="KR231_001135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR03905 family TSCPD domain-containing
                     protein"
                     /protein_id="HBH0003539.1"
                     /translation="MKYKTTGTCATEIEFEVKENKVTNVNFIGGCDGNLKGLKVLVEG
                     MNIEDVIQKLKGIECKTKPTSCPDQLSLALENYMNIK"
     gene            13873..14598
                     /locus_tag="KR231_001136"
     CDS             13873..14598
                     /locus_tag="KR231_001136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyl-gamma-aminobutyrate hydrolase
                     family protein"
                     /protein_id="HBH0003540.1"
                     /translation="MKPIIGILGNLIIMENGMFPGLERSYVNNDYINAVLKGGGSPVI
                     IPVNTDKEVIKKQIEMVDGVLISGGWDINPQLYGEETREETTFIYPEVDEFDLIAISI
                     ALELKKPILGVCRGLQILNVSLGGTLYQDNNLIEGSYIKHTQSSKRHVATHKVDVKEG
                     SILEGILGKQLLTNSYHHQSVNQLGKGLKAIAYSKDGIIEAIEKEDENFVVGVQWHPE
                     MMVDYCDKMEKLFKYFINICSNL"
     gene            14620..15933
                     /locus_tag="KR231_001137"
     CDS             14620..15933
                     /locus_tag="KR231_001137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HBH0003541.1"
                     /translation="MNEKNKMGLISIILLGINAVVGAGVFLLPGDAMKSFGVASIFVY
                     IFDMLLVLSMAFCFAEVAGKFNKNGAAYVYTKEAFGDFCGFEVGLMKWVIGCISWGAL
                     IVGFPTSLSAVWAPAGEPHIQKIIIVVMIVGLTIINLLGVSLSKIVQNVITVGKLIPL
                     ILFIGIGIFFIKGVNFTSSTMVPPGAGATEFGAAALLMFYSFTGFESIAVAAEDMENP
                     QKNIPIAIISVIVIASIIYILNQVVCVGILGDSLSSTSTPVADAARICFGNMGAGLVT
                     FGTLVSVGGICMCGAFVNPRSCVALADDKMLPRIFARKDKKGTPYVAIIATMLITIPI
                     ALSGSFAELAAISAVARFIQYIPTSLSVLVFRKKRPELVGTFKTPFGAVIPLIAVCVG
                     TWLLFQASMHQLIMGLGALAIGVPLYFIMKSYNRKVYDENLKKIV"
     gene            16139..16678
                     /locus_tag="KR231_001138"
     CDS             16139..16678
                     /locus_tag="KR231_001138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBH0003542.1"
                     /translation="MPTITLKNGVDVLIREGVREDAQSIIDFYNEVGGETHFLSFGKD
                     EYKISLEEQENAIESAKASDNSVKLIAFIDGEIVGIATIDSNQKAKGKHVGVLGIVVK
                     EKYWGIGLGKRLMLDLIEWCKSNGITKKITLVTNEENYNAIGLYKKVGFEVESILKKE
                     CYYNGVYTDLIGMSLLLGI"
     gene            16767..18752
                     /locus_tag="KR231_001139"
     CDS             16767..18752
                     /locus_tag="KR231_001139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428429.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-1,6-bisphosphatase"
                     /protein_id="HBH0003543.1"
                     /translation="MKNLCKISDDYLNSKLKYLKLLSKQYPSISKASTEIINLEAILN
                     LPKGTEHFITDVHGEYEPFVHVLKNGSGVIKRKIEELFSNTIRDSEKKMLATLVYYPE
                     QKLDLIIKQEENIDDFYRINIYRLIELCKYASSKYTRSKVRKLLPENFKYIIEELLHE
                     HVKSEHKEEYYKSIVETIVDIGIAKEFIIAISTVIQKLVVDRLHVIGDIYDRGPRPDI
                     IVDKLIEHHCVDIQWGNHDILWMGAASGEKTCIANALRISARYANLDIVEDIYGINLL
                     PLATFAIEMYKDDPCKEFIPKVNDQSVTTTEKSLMAKMHKAISIIQFKLEGEVIRRRP
                     EFEMEHRLLLNMINYDEGTINLKGKTYKLKDTYLPTIDKKDPYKLTMEERNVIDKLVS
                     SFRGSEKLQKHVSFLFSKGSIYLKANSNLLIHGCVPLNEDGSFMSMNIMGKEYKGKAL
                     MDKMESLAREGFFFKDKAEEKLYGMDIMWYLWTGKCSSLFGKDDMTTFERYFIAEKET
                     HKENKNPYFKLRENEMACKRLFEEFDLELDESHIINGHVPVESKNGESPIKANGKILV
                     IDGGFSRAYQKTTGIAGYTLIYNSRTLQLVSHEPFNSAEEAIANESDILSTTVVVEHK
                     AKRKMVRDTDEGVKIQEEIEDLKLLLMAYKKGLIKEM"
     gene            18976..19944
                     /gene="spoIIIAA"
                     /locus_tag="KR231_001140"
     CDS             18976..19944
                     /gene="spoIIIAA"
                     /locus_tag="KR231_001140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage III sporulation protein AA"
                     /protein_id="HBH0003544.1"
                     /translation="MNKLSDEIINSLSTTIREKVEKVSNNNLNIEEIRLRSQKPLILN
                     ANSKDYFYNQKTMTLDLNQQNSYVVTREDVEQTFQIICKYSIHSFMDDIKKGFITLRG
                     GHRVGLVGKAIVEDGQVKNIKHISSLNIRVSREIIGCSDKILSHIIKGKNQINNTLII
                     SPPQCGKTTLIRDIVRNLSNGNEDYGFKGLKVALVDERNEIAGAYLGVPQMDVGIRTD
                     IIETCPKDLGITMLLRSMSPNVIVTDEIGSEKEIKALYTALNGGIGLITTVHGDSIED
                     IQNRKELNRLLDKELFKKVIILSAKRGAGTIEKIYDLEEKRWYFAN"
     gene            19934..20455
                     /locus_tag="KR231_001141"
     CDS             19934..20455
                     /locus_tag="KR231_001141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage III sporulation protein AB"
                     /protein_id="HBH0003545.1"
                     /translation="MQIKIIIIAFLIGSSYLIGEQIYKTYTRRHKQLNDLIRVLEILR
                     MDLSFGLYTLEEIFNRIGGNKEFCFWKFFYQISEGLHNEQSKTLEIIISENIDVLSKE
                     TYLGNKEIEELKNLILTLGKSDIESQQRMIDLSIENLKKQTYETKEDINKKGVLYKKL
                     VTFIGIGICIILI"
     gene            20472..20669
                     /gene="spoIIIAC"
                     /locus_tag="KR231_001142"
     CDS             20472..20669
                     /gene="spoIIIAC"
                     /locus_tag="KR231_001142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018589775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage III sporulation protein AC"
                     /protein_id="HBH0003546.1"
                     /translation="MEISLILKVAGVGILISVLNMILEKTDRKDWAGLTTLAGVIIVL
                     GMVITEISDLFNTVRTMFQLY"
     gene            20685..21071
                     /gene="spoIIIAD"
                     /locus_tag="KR231_001143"
     CDS             20685..21071
                     /gene="spoIIIAD"
                     /locus_tag="KR231_001143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage III sporulation protein AD"
                     /protein_id="HBH0003547.1"
                     /translation="MEIMQLIGIAIISTTLCLVIKKDRPEIANFIAIITGVIILLSVM
                     FKLNFIVDSIQDLANKANIPTMYISLIIKLIGIAYLMEFAIQLCKDCGEGNIASKLEF
                     GGKIIVMSMSFPILLSIVEMVVNIIP"
     gene            21156..22361
                     /gene="spoIIIAE"
                     /locus_tag="KR231_001144"
     CDS             21156..22361
                     /gene="spoIIIAE"
                     /locus_tag="KR231_001144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage III sporulation protein AE"
                     /protein_id="HBH0003548.1"
                     /translation="MKKRFLPMIIGFLFTFFFVNIFAIMIFANEVPSSEDKEYGETKN
                     SIDKYIDGQLDKLDINEIQDYINKEIVINDVNLKSFVKDLISGEKNILDLFNKDGLKI
                     LMFDEFKASLKVVAVILVLALLSSILKSLENSFSSGAVSQIATYIIFITMVSLTLIGF
                     KDVLQICYDAIDHTVGLMQVIMPILITFLLLIGFPITSTTLNPIFIGGVTFINVFFKN
                     FLFVSITVAFGILIINNLSKNIRLKRFFSFVKQINYVSIGAMFTVYLGLVSIQGLYVT
                     SFDKFSVKTAKFAIGNFIPVVGGFVSDSVDILLSSSQLIKNIFGGIGLILLVGICLLP
                     VIKILSVIVVYKLAAIIVEPVGEDGISNFLNEVANLMIIMLASVIAITVMFFVTVAIL
                     TSISVVSQG"
     gene            22421..23038
                     /locus_tag="KR231_001145"
     CDS             22421..23038
                     /locus_tag="KR231_001145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage III sporulation protein AF"
                     /protein_id="HBH0003549.1"
                     /translation="MLEGIKAWIVSVLIGAFIVNIVDMILPSSKIKPYVNLVLNFMFV
                     FIVITPVVGFFSKDMSLEDRILKSMGNYNKQYVDSTNALAKETGNNSLSKGYEDGLKE
                     VLKLKLDEYGYDLEDIELNGANINNIKIKEKNNSAKSNNSSNEENKNNSTKREEENIN
                     SNDKENSKQVFKKGTEYGLNLNEEKLKNDLIKVLDVSIEDIQIDK"
     gene            23050..23604
                     /locus_tag="KR231_001146"
     CDS             23050..23604
                     /locus_tag="KR231_001146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage III sporulation protein AG"
                     /protein_id="HBH0003550.1"
                     /translation="MLKNLNDKDKRKVYSLITIAGICVVSLVLLSCFPSSKSDKQVGK
                     TETNKNAEKQVTKEQEKDDLESKLTAILSKIDGAGDVDVMVTFESSEEIQPAFNSNNT
                     TETTEEKDAQGGERTVTTSSENKTMITSNSSDPVVIKTTEPKIKGVIVVASGASDPSV
                     KETLYSAVQTSLQVAGHQVEIYSK"
     gene            23631..24320
                     /locus_tag="KR231_001147"
     CDS             23631..24320
                     /locus_tag="KR231_001147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpoIIIAH-like family protein"
                     /protein_id="HBH0003551.1"
                     /translation="MKFNYKGRGFVIITLTAMLVVVGTVNYQLSKKSLLETSKEFKAY
                     EEAQLQKNTDDSYSSKTEDSSNVDKQGGKESADIDIVDSKASKVKEKATETSKEIKAQ
                     LSSEKNMKKASYILDMKMNREKQRNELVQDLNEMINNPSTTEESRKEASNMKLNIVKI
                     QEKELQIENLLSTKGYEEALVYISDNKVNVVVNEAKLEKKDAAKIFDLVAEQANVKYE
                     NIKLTNNNSNK"
     gene            24430..24792
                     /locus_tag="KR231_001148"
     CDS             24430..24792
                     /locus_tag="KR231_001148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HBH0003552.1"
                     /translation="MEDNKFGQVKISNDVIATIAGLAALEVEGIETTATLTDKLLKNN
                     GVKIQIEEEDVNLDVMVTIKYGMSIPDTAFKVQENVKNTVETMTGLKVSQVNIHIQGI
                     SFKKDKVDKEEAKATKKN"
     gene            24877..25383
                     /gene="nusB"
                     /locus_tag="KR231_001149"
     CDS             24877..25383
                     /gene="nusB"
                     /locus_tag="KR231_001149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antitermination factor NusB"
                     /protein_id="HBH0003553.1"
                     /translation="MKKDRAQKSTTREYIMKLIYQININKEDFETLEDKVDNFLKDNS
                     EHIINRYKELALQYSKNTNLKLEDTEIEDVIDKKYINTVCKALKENHDKIDELINKHA
                     KNWTVDRMPKVDVSILRLSVCEILYLDTPNKVSINEAVELAKIYCDDKSPKFINGILG
                     SVVDEIGK"
     gene            25367..26437
                     /locus_tag="KR231_001150"
     CDS             25367..26437
                     /locus_tag="KR231_001150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-sialoglycoprotein endopeptidase"
                     /protein_id="HBH0003554.1"
                     /translation="MKLGNNIIIGIDTSCYTTSIAAISLDKKVIFNEKIMLEVRDNSK
                     GLRQSEAVFQHINNLGILSDRIKSFKDKFNVEGVCSSKKPRPVENSYMPVFNVGHNFG
                     KLLSSIYGCRFYETTHQENHIEASLLNSKLKNNNKFISVHMSGGTTEILLTSKQDSHH
                     NVCDTNLGKIAKISIKKDDKSKLYNNFGYNIDIIGGSKDISFGQLIDRVGIKLGYKFP
                     SGKYLDENALNCNLKIESGLKTSVRDGYMNLSGLENQVNKIINDNGDNTNQKEYISKL
                     VLDSVVRNMFKSLVYLCETYNVNEVVFAGGVSASKYILRELSMKLRKKHIEAYFTEPQ
                     YSTDNAVGCAIIGLNNFLGERV"
     gene            26434..27639
                     /locus_tag="KR231_001151"
     CDS             26434..27639
                     /locus_tag="KR231_001151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII large subunit"
                     /protein_id="HBH0003555.1"
                     /translation="MKLRALDISEANSYIKRILINDPILSNLKVKGEISNFKVHSSGN
                     VYLSLKDETSKLNCVIFKSNFNRNLKLDNGVKIIANGYISVYERDGAYQLYINEIEIE
                     GIGNLHIEFNRLKEKLNKEGLFDPKYKIPIPKMPNSIGVITSPTGAVIRDIINVIKRR
                     YPKVNIKLYPVTVQGDKSAEEICEAIRFFNHMKNVDTLIVGRGGGSIEELWSFNDEMV
                     AREVFNSQIPIISAVGHETDFTICDFVSDMRAPTPSAAAEIATPSLDDINYKLGNIKS
                     RMSKSLTNQIELDQYRLETVFNKINNYLDSYTIKDKVIQLDKIYDKIIFGIENNLKLE
                     DEKLVKIGALLHNLSPLATMDRGYSITQKNGKVINSIKGLKIKDSIDIVLKDGNLECM
                     IDKIENKEG"
     gene            27641..27856
                     /gene="xseB"
                     /locus_tag="KR231_001152"
     CDS             27641..27856
                     /gene="xseB"
                     /locus_tag="KR231_001152"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419178.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII small subunit"
                     /protein_id="HBH0003556.1"
                     /translation="MNLTYEEAYKRLESILSELESKNASLDESLSLYEEGISLYKHCN
                     KLLDDAKLKISKFNQLGIEEDFKIEEE"
     gene            27859..28746
                     /locus_tag="KR231_001153"
     CDS             27859..28746
                     /locus_tag="KR231_001153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyprenyl synthetase family protein"
                     /protein_id="HBH0003557.1"
                     /translation="MEFKQCLKEKASFVEKVLKEYMPKEEGYQKTVIEAMNYSLSAGG
                     KRLRPILTLEACKIVGGNEDEAIPFAIAIEMIHTYSLIHDDLPALDNDDLRRGRPTNH
                     KVYGEAMGILAGDALLNYAFEVMLAGSINKENPEKYLKAINEIAKGAGIYGMIGGQVV
                     DVESENKQIEKEKLDYIHMNKTAAMMVGCMRAGATIGGANSEQMEEITKYAKNIGLSF
                     QIVDDILDIVGDEAKLGKKVGSDIENHKSTYPSLLGLDKSKEIAHNLIDEAKKSIEKL
                     SDDVDFLKGLAEYIIDREY"
     gene            28776..29213
                     /locus_tag="KR231_001154"
     CDS             28776..29213
                     /locus_tag="KR231_001154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="divergent PAP2 family protein"
                     /protein_id="HBH0003558.1"
                     /translation="MDFFSEIFNNGALGISLIACFLAQFIKIFTGKEKRIELSRILIS
                     GGMPSSHSSFVTSLATVVGIEKGFNSTDFAIITVLALIIMYDAAGVRRAVGKQATILN
                     QMVADIQHGKHIEQKKLKELIGHTPLEVWFGALLGIVTALILM"
     gene            29247..31112
                     /locus_tag="KR231_001155"
     CDS             29247..31112
                     /locus_tag="KR231_001155"
                     /EC_number="2.2.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-deoxy-D-xylulose-5-phosphate synthase"
                     /protein_id="HBH0003559.1"
                     /translation="MYKYLDKVNSPKDIKNMSIEEMDLLAKDIRKFLVKSVSKTGGHL
                     ASNLGVVELTLALHKVFDSPKDKIVWDVGHQSYVHKIVTGRKDCFVSLRQFNGLSGFP
                     KENESPHDIFDTGHSSTSISIATGIACARDIKKENYSVISVIGDGSITGGMALEALNQ
                     LGYIDTNMIVILNDNEMSIDKNVGGMSKYLSSIIRNSTVEKMTDEVDKILNVTQTGEI
                     LSKTAHRFKDKLMYSFSPQDCSFFDSLGIRYYGPIDGHNTKELIDILRKAKHKKGPVL
                     LHVITKKGKGYRFAEEQPDKYHGVSKFDIKTGVTSAKVKSMSISVGEKLVDMANSNEN
                     IVAITAAMPSGTGLNLFESAYPKRYYDVGIAEQHATGFAAGLAKNGMKPYFAVYSSFL
                     QRAYDQVIHDVCITKKPVTFLIDRAGLVGNDGETHHGMFDLSYLNSIPNIVVMAPKDT
                     REMELMMDLSLKLDCPLAIRYPRGSSYYLDKGEYGEIVLGKYEVLDDGQDTVILCIGS
                     MVKHALEAKEILSREGINPTIVNARFLKPIDEGMLKALLKNHKNVVTIEDNIVTGGFG
                     SRINKFIIDNEYNVNILNIAIPEEFVKHGNIDELYDFVGLSPKSIADKIRKLVIE"
     gene            31245..32057
                     /locus_tag="KR231_001156"
     CDS             31245..32057
                     /locus_tag="KR231_001156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TlyA family rRNA
                     (cytidine-2'-O)-methyltransferase"
                     /protein_id="HBH0003560.1"
                     /translation="MKKRIDLLLVEQGYFESRERAKKAIMAGLVFVDNQRCDKAGTEV
                     KEDCSIEVKGNPIPYVSRGGLKLEKAMKNFDLTIDGKVCMDIGASTGGFTDCMLKNGA
                     IKVFSIDVGYGQLAWKLRQDDRVVCMERTNIRNVTIEDTKQFADFASIDVSFISLKLV
                     LPKAKELVRHDGEVVALIKPQFEAGREKVGKKGVVREKSTHIEVIKMISDFSVENGFE
                     ILGLDFSPIKGPEGNIEYLIHLRNGNEGYEFDGETYNNKIVEVVEASHNLDK"
     gene            32077..33756
                     /gene="recN"
                     /locus_tag="KR231_001157"
     CDS             32077..33756
                     /gene="recN"
                     /locus_tag="KR231_001157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecN"
                     /protein_id="HBH0003561.1"
                     /translation="MILELYMKNCALVEELRLNIDKNLNILTGETGSGKSIIIDALGL
                     CLGDKYDRSFLRKGTDKGLVEAVFFSDNRYLKKILEENDISMEDDNLLVITRLIYSDG
                     KSTARVNGRTVKVSLLKEIASTLIDIHGQHQNQALFNKDTHLKFLDLFGENELEEFKI
                     AYKNVYHKYSEVKKALNCLTENKDEMQIQREIDLLRFQINEIEAANLNKNEYEDLLKQ
                     REVYRNSEKIYNNLNSSYSKLHNGEYNVIDLIGLASKELNDISKYDSVLSEYSDTVER
                     IMYELQDISGEIRNYKDNIDFEPYELEQIELRIDEINNLRRKYGDSIDDIFEYYGKIK
                     DRLDEILNRDERVEQLRSKLMNIEEDLKIKASKLTKARIEVATTLEKILLDELKSLNM
                     KNVMFKVNFEKGPFTLDGVDDIEFMISFNLGEDIKPIYKVASGGEMSRFMLAFKTILA
                     DIDDIDTLVFDEIDTGISGIAAQIVGEKLSDIAKKKQIICITHLPQIAANADTHYCIE
                     KDTSNNRTFTNVSKLNESQRKNEIARLIAGNNITEKTIEHASEIIELAKKC"
     gene            33971..34837
                     /locus_tag="KR231_001158"
     CDS             33971..34837
                     /locus_tag="KR231_001158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0003562.1"
                     /translation="MNKKDTMHLIFIIVIFILLWYIVVAVSEINKNIESCSNKLDYLS
                     QELMSTKSDISNTINEEMSKSYITKSIDLKVKKIEKKECIIDIDVQLSKLGKNGKVFF
                     MYKEDSDKWNETEMTKHGELSYACEIKINTGSEYDYKVVTSGAISESSDVQKLTKSDY
                     MPEQPIFNSGIRDNREYFIEIVENSNLFNHESEKSKNKVYDNIRLEKVDIIVNEGKKD
                     TIYKAKLAEGLDDGKTNNSNRNQVNYEVSFPKRDIDDIIYIKAKLTYNNGVEYTKDIT
                     EDITMGLQDLEK"
     gene            complement(34930..35421)
                     /locus_tag="KR231_001159"
     CDS             complement(34930..35421)
                     /locus_tag="KR231_001159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBH0003563.1"
                     /translation="MADKMAQNITLQFVEEKDLENLENVKLLFTEYSNSLNIDLCFQD
                     FNNELKTLPGKYKKPSGSLILAFVDENLAGCVALKKLEGKICELKRLYVRNQFRGLKI
                     GKILLEEIIEEAKKFGYTHMRLDTLPSMKSAQGLYEKFGFYDIEPYTYNPIEGARYME
                     LKL"
     gene            complement(35482..35922)
                     /locus_tag="KR231_001160"
     CDS             complement(35482..35922)
                     /locus_tag="KR231_001160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBH0003564.1"
                     /translation="MKLNVRIADINNWHDLVSLSVDKSQLDYIESNALSIAESKFITA
                     WVPVGIYDENSLIGFAMYGRLEDDRVWLDRFMIDSKYQGKGYGKASLDFLVNHLKNEY
                     NCDELYLSIFEDNKMAIKLYKDFGFEFNGELDYGGEKVMVLKSN"
     gene            36083..37141
                     /locus_tag="KR231_001161"
     CDS             36083..37141
                     /locus_tag="KR231_001161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase S55"
                     /protein_id="HBH0003565.1"
                     /translation="MNKINKNFKNIWIILGAVSIFTMVIIFNKNCNVNKETQIEAFTI
                     KNHDKKFVYPMGNIIGVKANTDGVLVLGYEEEDVDYIGGIQIGDNIVKIDNKRIKNSQ
                     DVSEILNKIKKSKVEVTFERKNKYKTEVIETKKENGKYKLGLWVRDKISGIGTMTFYD
                     PSMEKFKAIGHAIKDSDTNELLKIKQGYIYKPEQLKIVKASNEKVGKIKGDFNDSNLM
                     GNFSNNSELGISGNITENHNKEFNVANKEKQLIEVGRPQDVKIGGAVILFEDKNKNIT
                     SYDIKIESIVYDKGNYRDMVIKVVDDKLLEYTGGIVQGMSGAPIIQNNKIIGAITHVF
                     RDNPKKGYGIFIDEMIKL"
     gene            37283..38107
                     /gene="spo0A"
                     /locus_tag="KR231_001162"
     CDS             37283..38107
                     /gene="spo0A"
                     /locus_tag="KR231_001162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sporulation transcription factor Spo0A"
                     /protein_id="HBH0003566.1"
                     /translation="MGGFLVEKIKIVLADDNKDFCQVLKEYLSNEDDIDILGIAKDGI
                     EALDLVKKTQPDLLILDVIMPHLDGLGVIEKLNTMDIPKMPKIIVLSAVGQDKITQSA
                     INLGADYYIVKPFDFVVFINRIRELVSNRVTQVEPKPRPVQETQMTRSDFVKNVGNIE
                     TEITNIIHEIGVPAHIKGYLYLREAIKMVIDNVELLGAVTKELYPSIAKKFNTTPSRV
                     ERAIRHAIEVAWSRGKVDTINQLFGYTVHNTKGKPTNSEFIAMIADKLRLEHSMVK"
     gene            38520..39641
                     /locus_tag="KR231_001163"
     CDS             38520..39641
                     /locus_tag="KR231_001163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0003567.1"
                     /translation="MRVEAPIKVDRKTKKLAKRVESGEIAVINHIDIDEVAANSLVEA
                     KIKLVINAAPSISGRYPNKGPGILTENNILIIDNVGEELFEELKEGETIEVVDGKIYR
                     KGKFLGAGEVLDKYEVSHQIKAAYENLAVELDRFIDNTIDYAKKEKGFILGEVEIPKV
                     KTNYANKHVLIVVRGQDYKEDLSTMLSYIEEVKPVLVGVDGGADALIEFGYTPDVIVG
                     DMDSVSDEALKKASEIVVHAYTDGRAPGLKRVEELGLDAVVFPAPGTSEDIAMLIAYE
                     YKAELIVAVGTHSNMIDFLEKGRKGMASTFLVRLKIGSKLIDAKGVNLLYRSKLKIKY
                     IWALIATALFPVLVVASLSPGVQQFIQLMQLKFRVLLQM"
     gene            39659..40534
                     /locus_tag="KR231_001164"
     CDS             39659..40534
                     /locus_tag="KR231_001164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper transporter"
                     /protein_id="HBH0003568.1"
                     /translation="MHINMKYYIVTIGAIFIALGIGMLVGFNLNNNQQLSEQQANIIN
                     DLDDKFDILKEKNDKLDSDLASVNRDYEEAVNFINKNVDKILAGSLNGKSIGIISANE
                     NDDYTKNIEDIINKSNGSIAFNIILKENITNPEKLKEMSTKLGTDVKNANDAVNYIID
                     TLKKEDASDILTYLQELDVIKFNFIGDTYLKYDSVVIAGGNDAKDSTKQFEKIEKFVV
                     SKLKSENKYLVEVQNTGVKTSYVELYSKNKVATIDNIDEGIGSISLAILLQQGNIVGN
                     FGRLDTATSLLPSIK"
     gene            40558..41250
                     /locus_tag="KR231_001165"
     CDS             40558..41250
                     /locus_tag="KR231_001165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HBH0003569.1"
                     /translation="MDSYISIIIPAYNEESRIKYTLESILDIKQINEIIVVDDGSIDN
                     TAKVVSELENEKIKFFKLDKNRGKGYALNYGIKLAMKNADIIGFLDGDLGSSAKEVEK
                     LIVPILNGEADVTIAKFPPAKRKGGLGFVKGLAKNSVFEMTGVELDATLSGQRIFKRE
                     VLEKFDEIPFGYGVEVGMTIDILKYGFKIKEVLVNMTHNETGRNLKGFIHRGKQYYHI
                     KKVLGQKKKEWR"
     gene            41258..42082
                     /locus_tag="KR231_001166"
     CDS             41258..42082
                     /locus_tag="KR231_001166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase"
                     /protein_id="HBH0003570.1"
                     /translation="MKDYILYTILLLTGLFGTYAVIPLFKNLLINGNVLRPNYKKDMI
                     PVSMGIVFLPMIVINGIILAFFTTEFKDLAYIFMFMFGMISMFFAGILDDVIGNRDVS
                     GLKGHFKSLFKGSLTTGGFKALFGGFVGLIVSVAISKDIIDIIVNTLIIALSTNLMNL
                     LDLRPGRAIKAYLFIMVIIFLTLTGFVQVLPLLIVPNVLAYFNYDLKARAMMGDTGSN
                     VLGISIGMLISFGYPFNIRLGWLIFVVIMHIFTEKYSLTKIIEKNKLLNFIDKLGR"
     gene            42087..43154
                     /locus_tag="KR231_001167"
     CDS             42087..43154
                     /locus_tag="KR231_001167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3866 family protein"
                     /protein_id="HBH0003571.1"
                     /translation="MISKRVGIVESIVSQTETLDDIRVNINGEIQRAYNYPKISGTIN
                     IGDEVVLNTTAVELSLGTGGYHFVITNLNNIESTLTEGGHIMKLRYTPLQIKVDSVEE
                     QESIYHDKFANFKGLEGLSVVVGTLHSMLTPFAASFKRNNPNKKLVYIMTDGASLPIY
                     LSKNVDTLKEKKLIDSTITIGNAFGGDYECINIYTALITAKEILKADAVFVSMGPGIA
                     GTGTKYGFTGIEQGSILDAVKKLEGRAIAIPRISFADKRERHQGISHHSMTVFKEIVN
                     VNVDIPITIYDDEKLNFIKEQINLNGLDKKHNIIYIDNNKTKEDLDYFNLKVKSMGRN
                     YEQDEAFFKAASTAAYYLMEV"
     gene            43156..43692
                     /locus_tag="KR231_001168"
     CDS             43156..43692
                     /locus_tag="KR231_001168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HBH0003572.1"
                     /translation="MVLEEKTISSDRVYTGKVITLKVDTVEIPGQGYQKRELVEVGGA
                     VGIVAITDDNKVVLVKQFRKPIEKPIFEIPAGKLEKNESPKECAERELKEETGYSAKN
                     IKLIHKFFTSAGFSNEIMFVYLATGLTPGENNLDADEFLDVYEIELEEAYNMVLKNDV
                     EDAKTSIGLLLVKDMFKN"
     gene            43760..44365
                     /locus_tag="KR231_001169"
     CDS             43760..44365
                     /locus_tag="KR231_001169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage II sporulation protein M"
                     /protein_id="HBH0003573.1"
                     /translation="MRRTYRKNDFRELNRQIIIIGLLFMMSIVVGSYINKILPGSSNN
                     ILNNINPAVEYYNLNISIKDTVIQNLKSDAIFMGSIALLSLFVVTIPAVLVAFVLKGM
                     SIGYTINSCILALKFKSIKMILIILFKNLIIIPCAIILALISLSYFKEMVYEFKKKNR
                     KNMQFLIKRYILNIIIIIALSLGLQLILNTASIGIIKFLAK"
     gene            44377..45291
                     /locus_tag="KR231_001170"
     CDS             44377..45291
                     /locus_tag="KR231_001170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HBH0003574.1"
                     /translation="MDIIEGYIDYIKDKKKLSENTVASYFMDIKKYMEYINQKSIKLV
                     DIVENDIISYLIKLEKDNVSIATIARMISSIKSFHDYLFLNHICTNNPAKDIKKPKIK
                     KENINILTEEEIERLLNFPKLTTPKLIRDKAIFEVLYGTGIKVSELVEMNIEDIDLDI
                     DYIYCNSCCKNQRVIPLCDITKLYLEKYLKEARPKMAVEGEKSLFVSSLGQRFTRQGL
                     WKVIKKYSNLANIDKNINPTMLRHSFAIHLLNEGANIAVVSKILGNVNLSSLQVYLNH
                     IDKNVRREIKEKHPRNDVDVELQKAEAK"
     gene            45333..46505
                     /locus_tag="KR231_001171"
     CDS             45333..46505
                     /locus_tag="KR231_001171"
                     /EC_number="5.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopentomutase"
                     /protein_id="HBH0003575.1"
                     /translation="MSRVIWIVIDSVGIGALPDAEKFGDSKDVSTLGNIFKEYPDIQI
                     PNMRNLGIGNIDGIDFFESIKEPIGCFGKCKEMSQGKDTTTGHWEMTGIIVDKPFKTF
                     EHGFSKEIIEEFEKKTGRKVVGNKPASGTVIIDEYGEHQIKTGDVIVYTSADSVFQIA
                     ANEEVIPLEELYNMCKIAREIMMGDNAVARVIARPFIGKKKGEFVRTSNRRDYSLDPF
                     EPTVLDNIKESGLDVLAVGKIEDIFNGKGITDAIHTKSNMDGVDETLNYMKQDNKGLI
                     YSNLVDFDSKYGHRRDPEGYKKALEEFDSRLPEIMANMREDDILIINADHGNDPTYKG
                     TDHTREYIPVMIYGNKIKKGFNLGVKDTFADIGATVADILNVKLPKHGSSFKEDLF"
     gene            46552..47364
                     /locus_tag="KR231_001172"
     CDS             46552..47364
                     /locus_tag="KR231_001172"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HBH0003576.1"
                     /translation="MFEKIAQSSKFINSKSDIKPKIGLILGSGLGDLANDIEDPVAIK
                     YSEIPNFPVSTVAGHAGQLVIGKLEGKEVIAMQGRFHYYEGYSQKEATFPVRVMKELG
                     VEILIVTNAAGGVNKEFKAGDLMLIRDHINFSGSNPLVGKNDDRFGARFPDMSDAYSS
                     KYVDVVKNCAKECNIDVKEGVYMFFSGPNYETPAEVRMAQILGADAVGMSTVPEVIVA
                     SHSNIGVIGISCITNMAAGILNQPLSHEEVIETTQKVKSEFMNLVKTTVKNL"
     gene            47568..48893
                     /locus_tag="KR231_001173"
     CDS             47568..48893
                     /locus_tag="KR231_001173"
                     /EC_number="2.4.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrimidine-nucleoside phosphorylase"
                     /protein_id="HBH0003577.1"
                     /translation="MRMYDIIKKKRDNLELSKKEINYFIENYSKGDIPDYQASALLMS
                     IYLNKMNKQETVHLTEAMMNSGDMINLSEIDGIKVDKHSTGGVGDKTTIALIPLVASC
                     GAPVAKMSGRGLGHTGGTIDKLESIPGFSTEMEISKFIDSVNKSKIAVCGQSAKVAIA
                     DKKIYALRDVTATVDNISLISSSVMSKKLASGADAIVLDVKTGDGAFMKTLEESFELA
                     KSMVDIGTGMNRDTIGIVTDMDEPLGFAVGNSLEVIEAIETLKGNGPKDLVELCEVLG
                     AYMLVLSKVAHDFEDGVEKIRESIKSGTAIQKLKEFIENQGGNKDVVDDYSLFKKSKY
                     KYPVKSTKSGYISKIKAEDVGVSAMILGAGRETKDDILDLSAGIILEKKVGDYVNEGE
                     VLAYMYYNDEQKLSLAKGRFIDSYSIVDSKIEKNKLIYGIVTKEEIKKF"
     gene            49106..50185
                     /gene="mltG"
                     /locus_tag="KR231_001174"
     CDS             49106..50185
                     /gene="mltG"
                     /locus_tag="KR231_001174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endolytic transglycosylase MltG"
                     /protein_id="HBH0003578.1"
                     /translation="MNFKENRLKIAVLIIVILIILAGIFVFIQIGPYDKNNKKDVIID
                     VPSGASVGKISDILYENKLIKNELLFKLLVKVSNKAPSIKSGTYLLNQSYSNNDIISL
                     LVSGKIYQDGIKVTIPEGATSKEIIAMLVSKNLGDKATFENLIKKPQEFYDKFPYLKE
                     DGITSLEGFLYPETYYFNSKKQSEEDILSEMLKVFDSKYTDKFKKKQKELNMTLQEVM
                     EMASIIEKEAVLDKDRPIIASVFYNRLKVGMPLQSDATIQYIFEERKKIVTYDDLKID
                     SPYNSYKNKGLPPTPISNPGIKSIEAALYPEKTDYLYFVAKIDGGNNYSTNYQDHLKY
                     VKEYKEARDKQSKDTKATNKENTKK"
     gene            50357..51031
                     /locus_tag="KR231_001175"
     CDS             50357..51031
                     /locus_tag="KR231_001175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-methyltransferase"
                     /protein_id="HBH0003579.1"
                     /translation="MSNIVNDLVEDYIRVTLKEKEGFLKDLEIYAEENSVPIIHKEVS
                     DLLKVLLKVQKPKRILEVGCAIGYSSIFFATIIGKDADIITVERNEKMIEKAKENIKL
                     AGFDNNITILEGDAEEKLSQVQGEFDLIFIDAAKGQYKLFFDLVIDKLKDGGLLVSDN
                     ILYKGMVAHDDFVVRRKKTIVKRMRNYLDYICNCDYLSTSLVPIGDGVALSYKESKRG
                     DVDGIK"
     gene            51018..52265
                     /locus_tag="KR231_001176"
     CDS             51018..52265
                     /locus_tag="KR231_001176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438167.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HBH0003580.1"
                     /translation="MELNKVELLAPAGDLERLKIAITYGADAVYIGGEIFGMRSAAKN
                     FSKEDMAEGVAFAHERGKKVFVTVNIIPHNEDFLQLEDYLLELEEIGIDAVIIADPGV
                     LSVIKKVIPNMEIHLSTQANTTNYLSANFWYEHGIKRVVVARELSFDEISEIRAKTPL
                     DMDIEAFMHGAMCISYSGRCLISNYMTGRDANKGSCAQSCRWQYHLVEEKRPGEYFPI
                     YEDERGTFFFNSKDLCMIEYIPELIKSGITSLKIEGRMKTAYYVATVVRAYRMAIDEF
                     YRDPENWKFNPMWMEELKKGSHRHFTSGFYLNKPTTEDQNYQSASYVRNYDFIGIVRE
                     TEDEDGLIVVEQRNKMCVGDEIEVMGPYKETMFTKIEEMYNEEGEAIESAPHPRQIVK
                     LKLSVKVGKDYMLRKVIEEKVEE"
     gene            52337..54001
                     /locus_tag="KR231_001177"
     CDS             52337..54001
                     /locus_tag="KR231_001177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein 2"
                     /protein_id="HBH0003581.1"
                     /translation="MSKKKTPFLKKVGKRSWCIFTIILIIYSVLIYRLVDIQVLKGDK
                     YKQSVESQSVEKVELNSGRGIIYDRNNKKLTDTSKSQVLIVEKEKLNNNYKILELIKK
                     ATKMNDLDIYKAVQEQLTRPIIQIQTKNIDKSMKKELEKNGIMVEEKTMRYAKDGLLS
                     HTIGYIKEDDKSGQSGIEKSMDSVLRNSNEKYISAFKAGDAGNEKSLNILKGSVKTVD
                     NKDKDRHLKTTIDYNIQKKLEQILNKEENPTAAIISEASTGEILAMCSRPNFDQNDIS
                     KSLKGKNGEFENRVIKATYPPGSVFKMVVLFSALENGVIDENYTYNCTGKTKVGNTNE
                     ILRCNKRDGHGFQNLRQAFSNSCNPAFLDIAMKLGKEKILKSAEKLHLFEKVDIGLDE
                     EKIREAPKNISIRNLAIGQENIEFTPLQINQMTQIIANNGTFKPLYLYKSLVDNNMNT
                     IKTYKSSKKEELISPYVCTQVKEYMKSVSRIGTAKDLKDIEGGCGVKTGTAQSSLNKK
                     AIDHGWITGFYPEERPKYVITVLVEGTQKGNKSATPIFKEICESIK"
     gene            complement(54098..54739)
                     /gene="sigK"
                     /locus_tag="KR231_001178"
     CDS             complement(54098..54739)
                     /gene="sigK"
                     /locus_tag="KR231_001178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018589741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sporulation sigma factor SigK"
                     /protein_id="HBH0003582.1"
                     /translation="MAALKSFEKPLTPEEEIEYLTKFKIENDKSAKDTLIERNMRLVA
                     YIAKKYNNSTEDQDDLISIGTIGLIKAIETYNIDKGTRLATYASRCIENEILMNIRSN
                     KKNKTQVSLQDPIGTDKEGNEISLLDILGTEANYVLDEVELKVQVGKLYEQLNKILTP
                     REREIVQLRYGLTPYGYKTQREIAQKLDISRSYVSRIEKKALKKLEKELVQES"
BASE COUNT        22355 a         5603 c        10271 g        17016 t
ORIGIN      
        1 tgatatatta tttatgaaaa tcgtttaatg tatacaataa tatatctata acaaaataat
       61 aaaagataga gttttattta gacatttatt acaaatcaaa atttattaca tattatttat
      121 aaaaaaatct aaggaggaaa taataatgaa aatattagta ttaaactgtg ggagttcttc
      181 attaaaatat caattaatag atatgaataa tgaagaagtt ttatgtatag gattggttga
      241 aagaatagga atagaaggtt ctatattaaa acatgaaaaa gcaggtagag atgataaata
      301 cgttgttgaa caaccaatga aggaccacaa agatgcaata gcattagttt tagaagctgt
      361 tgctcatcca gaatttggtg cagttaaaga aatgaaagaa atagatgcag taggacatag
      421 agttgtacat gctggagaaa aatttgcaac ttcagtagta ataactccag aagtagaaga
      481 agctttaaaa gaatgtatag atttagctcc acttcataat ccagcaaaca taatgggaat
      541 agatgcttgt aaagctatac ttccagatgt accaatggta ggtgtatttg atactgcttt
      601 ccatcaaaca atgcctaaat cttcatactt atatggttta cctcatgagc tatatactaa
      661 atatggggta agaagatatg gattccacgg aacttctcat aattatgtat ctcagagagc
      721 agcagagata ttaggaaaag atataaaaga tttaaaaata gtaacttgtc acttaggaaa
      781 tggtgcttct atagctgctg ttgatggtgg aaaatgtgta gatacatcta tgggattcac
      841 tccattagaa ggattaataa tgggaactag atgtggagat atagacccag ctatattacc
      901 attcttaatg agaaaagaag gtttagatgc tgatggattg gataaattaa tgaataaaga
      961 atctggagta tatggaatga ctggaatttc tagtgacttc agagatatag aagatgcagc
     1021 taaaaatgga gacgaaagag ctcaagctac attagaagcg tatgttaaaa aagtacaaaa
     1081 atatataggc gcttatgctg ctgaaatgaa tggattggat gttgtagtat ttactgcagg
     1141 cgttggtgaa aatggaaagg ctataagagc agatattgct tctaacatgg agtttttagg
     1201 aatgaaatta gataaagaag ctaatgatgt tagaggaaaa gaaacagtaa tatctactgc
     1261 tgattctaaa gtaaaaatgc ttttaatacc aactaatgaa gaattaatga tagctagaga
     1321 tacattaaga ttggtaaaat aattaaatta aacctatgcc tatcaagtaa aaatacttga
     1381 caaacaaatg ctagatttgt ataataaatt tggtgatatg ttgaggtgaa cttaatgaaa
     1441 gttagcatag aaaaaataaa tagaaaagaa actgacaaaa tagacttgaa tttttgtgaa
     1501 aaaattgata ctattagtta ttgtgatgag atttacaaat tagtatcacc tgtaaattta
     1561 aaagggaaag tgtcaaagac taataaaggt ttgtatctag atatagatgt caattttaca
     1621 attgttgaca attgttcaag atgtcttaaa gaagtagaaa taccactaga gtattctata
     1681 caaggttttt tagtaaaaga agaagattat gatgaagatg agtttgagga atttgatcct
     1741 tttatattcg atggtgaaga aatcgacctt attgatataa tagaacagac attagatttt
     1801 aatgtacctc ataaagttct ttgtagtgaa aactgtaaag gtctttgtca agtatgcggg
     1861 gcaaacttaa atgaagaaga gtgttcttgc agtgaaatta caaacgatga ggaatacata
     1921 gatcctcgtt ttgctaaatt aaaagattta tttaattaaa ttttgactaa ggaggtggcg
     1981 taaatggcag taccaaagcg taaaacgtct aaatcaaaca caaaaatgag aagagcagct
     2041 aactcaaaga tggaagcaac aggatttgta agttgcccac aatgtcatga gccaaaatta
     2101 ccacatagag tgtgtccaga ctgtggatat tataaaggta aagaagttgt gtctaagtaa
     2161 tagcttctaa aaagcatgta gagtatactc tacatgtttt ttttgtacat ataaaaaaat
     2221 aagatgattt actagagaaa ataagtggat tttatgcata ttaaaaaata gaaaaataat
     2281 aatataagta ttgaaaattt ttgtgtgtta ctatatacta ctattagtag ctggtactaa
     2341 ttacagctat aaaatttgga gggaacatga aaaagaaaag taaagcccaa agacaaaaag
     2401 agcttataga tatgctaaag acagatcctt tttatactga tgaagaatta tcaagtctgt
     2461 ttgatgtaag tatacagacc ataagattag atagaatgag tctaaacata ccagagctaa
     2521 gagaaagagt caaatcaata gcagaaactc agagttcaaa agtaaagact ttaggagtaa
     2581 aggaaattac aggagaaatc attgatttat ctgtagggcg attaggtata tctatgttag
     2641 aagttacaca ggacatgatt tactctaaga ctaatacttt aaaagatacg tatatttttt
     2701 ctctagcaga ttcattggca atggctataa tagatgcacc taaggttatt atgagagttg
     2761 caaatgtaaa aagttttaag ttgatagaac aacaagatag acttatagca aaagcagaag
     2821 tgtatagaaa tatagataaa aagcattatg taaaagttgt tatcaacaat aaagcccaag
     2881 agcaaatatt tagaggaaag tttatctttg aagaattaga ttaggaggga aattatgaaa
     2941 atagtaattg atggaatggg tggagataat gcacctaaat ctaatgtaga aggcgcagta
     3001 aatgctataa aagaatatca ggttgattta ataatcacag gagataaaga tttacttgaa
     3061 aaggaatttt caaattatga atttgataga aataaattag agatagttca tactactgag
     3121 attatagaaa acgaagataa accagtaaag gctataagaa gtaaaaaaga ttcatctatg
     3181 gtagtagcat taaatcttgt aaaagaagga aaggcagatg ctataatatc agctggaaat
     3241 acaggagcct tacttgctgg tggattattt gttgttggta gaataaaagg aatcgataga
     3301 ccttgcttat gttcagcaat accaaatgta aagcgaggaa tgacacttat agcagactgt
     3361 ggcgcaaatg cagattgtaa acctaagaat ctagttgaat ttgcagctat gagtaatatt
     3421 tattcaagaa aagttttagg tcttgaaaat cctaaggtag cattagcaaa tgttggacta
     3481 gaagaaggca aaggcaatga tttagtcaaa aggtcatatg aagaaattaa aaaattagat
     3541 ttaaatttta tagggaatgt agaagctaga gaagttataa atgcatacac agatataatc
     3601 atatgtgatg gatttacagg taatatatta cttaaatctg ctgaaggtgt agcactttca
     3661 gttatgagtc ttataaagga aacttttatg gccagtacaa aaagtaaaat aggagcatta
     3721 cttataaagg atgatttaag aaaattaaaa agttttatag attattctga gtatggggga
     3781 gctccacttt taggtctaaa tggaggagtt ataaaagctc atggtagttc tgatgctaaa
     3841 gctataaaaa atgctataaa tcaaggaata aaattttcaa agggaaaagt cgttgaagat
     3901 attaaccaat ttataagcaa atacaatgaa gaaaataaaa ataacgaaga tgaataaact
     3961 cgttttggag gtttaatata taatgaatac aaaggctgga atattaggag taggaagtta
     4021 tctacctgag caatcatatg ataattttca cttcgaaaaa ataatggata catcagatga
     4081 gtggataagt actagaactg gtattaagga aagaagattt gccaaagagt ctgaagcaac
     4141 ttctgactta gcatctaaag ctgccttaaa agctatagaa tgtgcaaagt taaacgtaga
     4201 ggatatagag ctgattatat tagctacaat tactcctgat atgtctttgc cttcaactgc
     4261 atgtatagta caagatgcaa taggagcagt aaatgctact gcatttgata tatcagcagc
     4321 ttgttctgga tttgtatatg gagtaactat tgcaaagcaa tttgtggaaa caggttgcta
     4381 taaaaatgtg cttgtaatag gagcagaaac ttgttctaag tttttaaatt atgatgatag
     4441 aacaacagca gtattgtttg gagatggagc tggagcagct gttattggcc ctgtaaatga
     4501 gggtggaata ctgtctacac atatgggctc tgatggtaaa ggaaaagatt gtttaaaagt
     4561 acctgctgga ggttcaagac ttaaggcaag taaagagact gtagaagcta atctacatac
     4621 aatagaaatg gcaggtagtg atgtgtttaa atttgcagtt agaaagatgg cagaaacttc
     4681 tttaagagct cttgaaaaag caaatctaaa tacaactgat atagactact tagtgccaca
     4741 tcaagctaat ataagaatca tacaagcttc ttctaagaga ttagagcttg atatgaaaaa
     4801 agtttatgta aatatagaca aatatggaaa tatgtctgct gcatctatac cagtagcatt
     4861 agatgaagct tatagagaag gtaaaattaa aaagggtgat aatgtagttt tagttggctt
     4921 tggtggaggt ctaacttggg gggcttcagt tgtcaagtgg actttatagt ataaaatatc
     4981 taaaatgatt taattaacaa aattaaactt atacacaaaa taaagttgat taataataaa
     5041 aagtttactt ttatgatttc aagtgaagga gaattgtatg aataaaattt gcaaaatatt
     5101 aaatataaaa tacccagtta tccaaggggg aatggcatgg gtagctactg catcattagc
     5161 aagtgctgta tctaatgcag gaggacttgg cataatagca gcaggaaacg caccaaaaga
     5221 agctataaag aaagaaattg ttgagtgtaa aaaattaaca gataaacctt ttggagtaaa
     5281 tgtaatgctt atgtcgccat ttgttgatga tataattgat ttgattatag aagaaaaagt
     5341 tcaagttatt actactggtg ctggaaatcc tgcaaagtat atggatagat taaaggaagc
     5401 tggaacaaag gttattcctg tagtacctac aatagctttg gcacaaagaa tggaaaagct
     5461 aggagctaca gcagtaatag cagaaggtac tgaaggtgga ggacatatag gagaacttac
     5521 tactatggtc ttagttccac aagttgctga tgctgtaaac atacctgtaa tagctgctgg
     5581 aggaattgta gatggtagag gaattgcagc atcatttgca ttaggtgcca gtgcagttca
     5641 agtaggaact agatttattt gcagtgaaga gtgttctgtc cattcaaact ataaaaactt
     5701 agtactaaaa gcaaaagata gagatgcaat tgtaacagga agaagtactg gtcatccagt
     5761 aagaacatta aaaaataaac tatcaaaaga atttttaaag atggaacaaa atggagctac
     5821 tcctgaagaa ctggataaaa aaggtacagg agctttaaga tttgcaacag tagatggaga
     5881 catagaaaaa ggttcattta tggcaggtca aagtgctgct atggtaaaag aaataacacc
     5941 ttgtaaggaa attatagagg ctatggtaaa tcaagcaaga gagattatgc cagcaataga
     6001 actgtaaatc aggaggagca agatgggaaa agttgcacta gtattccctg gtcaaggagc
     6061 tcaatatgta ggtatggcca aggatttata tgaaaataat actgttgcta aaagtgtaat
     6121 agatgaggct agtgatgcct taaatatgga tttaaaaaac cttatgttta atggaaatga
     6181 agaagaactt tctaaaactg aaaacactca acctgctatg gttacacata gtgtagctgt
     6241 attaaaagca gtacaagccc aagtagattt aaaatatagt gcatgtttag gtttatcttt
     6301 aggagagtat agtgcattgg ttgcagcaga tgcaattgac tttaaagatg ctgtatgctt
     6361 ggtcaaaaaa agaggtaagt ttatgcagga tacagttcca acaggtgttg gagctatggc
     6421 agcaatttta ggtctagata gaagtatatt agaaaatgta gttaaagata tacaaggagg
     6481 tattgtggaa gtagcaaatt ataattctcc tggtcaaata gttatatctg gtgaaaatga
     6541 aaagatagaa gaagcaatgg tgaaatgcaa agaagcagga gcaaaaagag ctgttaaatt
     6601 aaatgtaagt ggaccttttc actcatcaat gctaagagaa gctggtgtaa aattggccag
     6661 tgaattagaa aaagttaaca taactaaacc taaagttgat gtggtggcaa atgtaaatgc
     6721 agattactat aaaaacgaag gtaaagacct gcttataaaa caagtaagtt catctgttct
     6781 ttgggaagat tctatagaaa gacttttaaa tgatggatat gatactttta tagaaatggg
     6841 acctggaaaa actttaaaag catttattaa gaaaatagct tccaataaaa aagcaaatgt
     6901 caatatttat aatatagatg gtatagattc tcttaatgaa tttgtacaaa attatagaaa
     6961 tggagagata taatgataaa tcttacagga caagtagcag ttgttactgg tggctctagg
     7021 ggtataggaa aagaaatagc aaaaaaacta gcatcttttg gagctgatgt agtaatcaat
     7081 tatacttcta aagaagatga agcactaaaa actaaaaatg aaatagaaag tatgggggta
     7141 aagtgtacct ctataaaatg tgatgtgtct aaatttgatg aagtgaatca aatgatagat
     7201 tctgttgtaa gcgaatttgg aaaaattgat atattggtta ataatgcagg cataactaaa
     7261 gatggtctgc ttatgagaat gaaagaagaa gattttgata gagttataga tataaactta
     7321 aaaggtgtct ttaattgtac aaaagcagtt actaaaccta tgatgaaaaa gaagtatgga
     7381 agaataataa atatgacttc agtagttgga attatgggta atgcagggca aactaattat
     7441 tgtgcatcaa aagcaggtgt aattggattt acaaaagctt ctgcaagaga gttagcatca
     7501 agaaacataa atataaatgc agtagcacct ggatttatag aaacagatat gactaaagta
     7561 ctaagtgatg atgtaaaaga atcaacacta gcaaacatac caaagaaatc ttatggtaaa
     7621 ccagaagatg tagccaatgc cgtagcattt ttagttagtg acatgtcaag ttatataaca
     7681 ggacaagtaa taaatgtaga tggtggaatg gtaatgcaat aataatttaa aaagtagaga
     7741 aatctattaa aataaaaaat tttaggaggt acacaatgtt taataaagtt gtagaaataa
     7801 taatagagca attaggagta gaagataaag aaataactat ggaaacatca ttaatgaagg
     7861 atttagaagc agattcatta gatgcagtag aaataataat ggcacttgaa gatgaatttg
     7921 gtatagaaat accagataca gaagcagaaa acttcaaatc tataggagat atagttaagt
     7981 atatagaagc taataaatag tcgagcttta aaaaagtgga ggtatccgat gaataaaaga
     8041 gtagtaataa caggacttgg atgtgttacg ccgttgggaa caggaaaaga agagttctgg
     8101 agtaatataa aatctggagt atctggtata gataaaataa ctaattttga tgctagcaca
     8161 tatcaaactc agatagcagg agaagttaag aattttcatc cagaagaata tataagtaaa
     8221 aaagaattga agagattaga taaatttgct caatttgcaa tagtatctgc taaattagca
     8281 gttgaagatg caaatcttga tttagataaa gttgatagag aacgttttgg tgttataata
     8341 ggttctggaa taggtggagt tgaagctata gaaactcaac ataaaattct tttggaaaaa
     8401 ggaaataaaa gagtaagttc actttttgta cctatgatga taggaaatat ggcagctggt
     8461 caagtttcaa tatttttagg agcaaaaggg cctaacacta atgtatgtac agcttgtgca
     8521 tcaggaactc attcaatagg tgatgctttt aaggtaattc aaagaggtga tgcagacatc
     8581 atggtagcag ggggttctga agctgctgta acaggtcttg cttttgctgg attctgtaac
     8641 atgaaggcta tgtcaactag aaatgatgac cctaaaactg catcaagacc atttgataaa
     8701 gacagagatg gttttgtaat gggagaagga gcaggtattg ttatcttaga agacttagaa
     8761 catgctttag caagaggcgc taaaatatat gcagaagtag ttggatatgg tttaactgct
     8821 gatgcatacc atatgacaac tccagctgaa aatggagagg gagcagctag gtctatgaat
     8881 atggctttga aagaaggaaa tgttccatta gaagaagtag attatataaa tgctcatgga
     8941 acttcaactt attacaatga tttatatgaa actatggcta taaaaactgt atttggagaa
     9001 aaggcatatg acttatgtgt gtcatcaaca aaatctatga ctggtcactt attaggagca
     9061 tcaggtgcta tagaggctgt tgtttgtgct atgagtatag aagatagttt tgtgcctcca
     9121 actataaaca tacaagaagt tggtgaagat ttggatttag attatgttcc aaatcaaggt
     9181 aaagaaaaaa atattagata tgcactatca aattctttag gatttggtgg gcataatgct
     9241 acaatagtac taaaaaaata tgtataaata aatattaaat ataaaactaa aaaacaagca
     9301 cttgttttaa ctgtataaat ttatattagc ttaaatttaa agtctcctaa attattttag
     9361 gagacttttt tattaagatt taagtctagc atatgttgta aatcattttg atatattgta
     9421 ttattaatta ttaagaggtt atttatatat gtaagttttc attctacaat atacaaaagg
     9481 aggactaaaa ttttgaattt tagactacca aagaaaaggt tacccaaaaa gataattttt
     9541 atatgtataa tacttattag tattattttg tttataaagc atgaccaaaa tggattgaaa
     9601 gaaagagaaa ttataaataa gggaaaatat atgtctgaaa gccttgtggc agataaggag
     9661 tatgatgaag caaaaaaagt ggttaagact tctttcgaat ctattccaga aaaaaaatac
     9721 aataaagtat ataatgaagt ttgggatatg ttaaagacta tttcatatgt tccagatgga
     9781 acgaagatag tcattgattc tttagaaaag atgagagaat cagatgtgaa attatctgat
     9841 gaatgtagat ttaatataga aaaaagatta gcatcagtgt atataatgga taataattat
     9901 tttaaggcag tagatttaac tgtaaagtct ataaagttgg ctgagaaatt ggggaataat
     9961 tatgaaaaag caagactaga tgttgatttg gcgagcatat ttttaaagat aggtggctat
    10021 gaaacaggag agaaattaat aaaggattct tttaaaatag atattgatga aggtgaaaaa
    10081 aatggaatgg ttagattata tgctattata aatctagcag aaatatatgt agaagagggc
    10141 gaatatgata aagctattga aataagtagc aggataaaag attataaaaa gtttgtaaat
    10201 acggataatt acaatgattt tgatataatg gcctctataa tgcagtcaaa tgcgtatgtg
    10261 ggcaaaaata atatacaaaa ggcaaagact tttttagaaa aagctgatta tcttataaaa
    10321 tcagatagaa cagtttatat attagataaa gatatgtact attatatggc aatgggaaac
    10381 ttagaatata aaagcgaaaa ttataattct gcaatagata attataaaaa aagtttagag
    10441 atatctacta aaagaaagtt aacccaggag aaaataaaaa atttaaataa gatattaaat
    10501 atatatgaaa aacaaggaaa tatagaatct ttaaatgagt atcaaaagat gttaataaat
    10561 gaatataaag agaacaaaag tataagagat tcagagacta gtttctatat aattgataaa
    10621 gtatcaaacg aaagtaagct atttgaaaaa actaaaaaag aaataaaata ttataaaata
    10681 ttatttacag taattttaat tgctatatta gggtctactt ttttatacaa ccgattgaag
    10741 tattttaaag cacaaaattt acatgatggt cttacaaatg tttataatag aaaaagtttt
    10801 gatattatgt atgaaaagta cagagagaaa gatgataatt ttgcacttgt gatgatagat
    10861 attgataatt tcaagctcat aaatgataat tatggacata aatttggtga cactgttata
    10921 aagggaataa caaataccat ttgtgttatg ttagaacaag atgataaagt ctttaggtac
    10981 ggaggagaag aattttctgt attaataaga aataaatctg gtgatgaagt agcagatata
    11041 attgacagta taagggttgc aattgcaaat aaaaagtgga atgatgatgt gactgtgact
    11101 ataagtgcag gtgtagctca tgtttcagat agcaaagatg tactagaaga agctgataaa
    11161 aatttatata aagcaaaaca acttggtaga aataaagtag tatataagta attatatact
    11221 atataaataa gaggtataaa tatgaaacaa tcaatagcta tagtaactga taaaataact
    11281 aaactatcat ctttcttaga agaaaatata cgtttggttt taggtaatta tattgatata
    11341 aaccactatt atctggaagt tttaaaagag aatgataaaa tacaaggtga ttttgtacta
    11401 gtaatgaatg atgatagatt aaacagtatg agaaagcatt tagtacaaga tagtaagatt
    11461 atagtgataa ggagaacact taaagaaaat gaaatatatg gattattttc aataccaaat
    11521 ggaactgaag tattggttgt aaatgataca aaagaaacta ccttagaaac gataagctta
    11581 ttttacaaaa taggagtaaa aaatttaaag tttactccat atattgaagg aaaaatttat
    11641 aaaaatatag acatagctat aacgcctgga gtaaagggaa aagtaccaag ttatataaat
    11701 aaagtaatcg accttggaaa tagatatatt gatatatcta cctttataga aataataaat
    11761 ggtcttagaa tagatgttaa agaaatacgt aaaaatttaa tggcatattc tgagagttta
    11821 ataagtttag ataatggagt taaagataat tataggcaac tgtttttaaa aatagaagaa
    11881 caagatgtta tattgaatct atcaaaagat ggaataatat ttacttcagc agatggtata
    11941 ataaacacat ttaataaaga agctttaaaa attttaggta taaatgaaaa tccacaaggc
    12001 aaaaacatag aagatatcat ttctgaagat ttaaatattt tacttgaaga caaagaaata
    12061 attgatgaag tggtatttac aaataaaaaa tatataaatg taaataaaaa aagtattttt
    12121 tctatgggga ataaagctgg gatatattat aacttacaag aaataacgta tataaaaaaa
    12181 ttagaacaaa atcttactaa taaattaaga gaacaaggtc agatagcaag atatacattt
    12241 aaagatataa aaactaaaaa taaaaatatg gtaaagtgtg tagaattggc taaaaaaata
    12301 tctaaatcag aactttctgt attaataata ggagaaagtg gtactggtaa agaattatta
    12361 tcacaatcaa ttcataatgc ttccaataga agtaatcaac cgtttatagc agttaattgt
    12421 gcagcagttc cagatagtct attagaaagt caactgtttg gatatgaaaa aggctctttt
    12481 acaggagctt taagagaagg aaaaaagggt ctatttgaac ttgctaataa tggaactata
    12541 tttctggatg aaattggaga tatgcctcca ttgctacaga caaagttact aagggtatta
    12601 caagaaaagc aggttatgcc tataggttcc cataatgtta taaacataga tgttagggtc
    12661 atagcagcaa caaacaaaaa cttactaaag atgattagag aaggaaaatt tagagaggac
    12721 ctgtattata gactaaatgt attgccaata gatgtaccat cattgaggaa tagaaaagaa
    12781 gatataataa cacttatgaa tttctttttg aaaaacaata taagactttc gccagaagtt
    12841 ataactattt tagaaaaata taattggcca ggaaatataa gagagttaca aaatgttgct
    12901 tcttatgtaa gtctaatgtg tgatagtatg gtttttagag atgacttacc accatatata
    12961 agggtagaat gtgctaacaa ttatgaagat ggatttggtt atacaagaaa agaatttgag
    13021 gaaatactga ggattctata tgaaagaaga gagtcatcct ctggaattgg aagagggttt
    13081 ataatcgaaa agcttataca ggaaggtatt gagatttctg aaagcaaagt tagaaaggtg
    13141 ctatcttatt taagtgaatg tggatacata tcatctaaat ctggtagagg aggaagtcaa
    13201 ataacctcag aggggataaa actttataat aatataaatt aagctaagta tttgatattg
    13261 aaatcacata ttttgaattt agatatttaa ataataataa acttttatat ttatagagat
    13321 taatttatat tatgtcagaa agaatattgt aatttataat taaatattaa taggttttta
    13381 aaataggatt agataggtaa taggttaagt tagaataacc cattacctat ttttatttgt
    13441 aagaaaagtg tacatagaat tagaagtaaa aaatacaact aataaaacta ttgaaaatac
    13501 tagataaata ataaataaaa ataattatag attttggcat acatattgct aattatagag
    13561 ataagacgac aaaataattg ggaggtttaa tgatgaaata caaaacaaca gggacttgtg
    13621 ctacagaaat tgaatttgaa gtaaaagaaa ataaagttac aaatgtaaac tttataggtg
    13681 gatgtgatgg aaatttaaaa gggctaaaag tattagttga aggcatgaat atagaagatg
    13741 taatacaaaa gttaaaagga atagagtgta aaacaaagcc aacatcttgc ccagaccaac
    13801 tgtctctagc attggaaaat tatatgaata taaagtaata cataaaacaa tcgattagtt
    13861 aggagtttaa ttatgaaacc aataataggg attttaggaa atttaataat aatggaaaat
    13921 ggtatgtttc caggtcttga aaggtcatat gtaaataatg attatataaa tgcagtgcta
    13981 aaaggaggag gtagtccagt aataattcct gtaaatacag ataaagaagt tataaaaaaa
    14041 cagattgaaa tggttgatgg agtcttaata tctgggggat gggatatcaa tcctcaactg
    14101 tatggagaag aaacaagaga agaaacgaca tttatatatc cagaagtgga tgaatttgat
    14161 ttaattgcaa taagtatagc attagaactt aaaaagccta tattaggtgt atgtagggga
    14221 ctacaaattt taaatgtaag tttaggagga actttatatc aagataataa tcttatagaa
    14281 ggaagttata taaaacatac acaatcttct aaaagacatg tagctactca taaagttgat
    14341 gttaaagaag gaagtatttt agagggaatt ttaggaaaac aattacttac aaatagttat
    14401 catcatcaaa gtgtcaatca gcttggaaaa ggattaaaag ccatagcata ctcaaaagat
    14461 ggtataatag aagctattga gaaagaggat gaaaattttg tagtaggagt acagtggcat
    14521 ccagaaatga tggtagatta ctgtgataaa atggaaaaac tatttaaata ttttataaat
    14581 atttgttcaa atttataata taccttgggg ggattgaaca tgaacgaaaa gaacaaaatg
    14641 ggattaataa gtattatact tttaggtatt aatgcagtag taggagctgg agtttttcta
    14701 ttaccaggag atgcaatgaa atcatttggt gtagcaagta tatttgtata tatatttgat
    14761 atgttgttag ttttatctat ggcattctgt tttgctgagg ttgcaggtaa attcaataaa
    14821 aatggtgctg cctatgtata tacaaaagaa gcttttggag atttttgtgg ttttgaagta
    14881 ggtcttatga aatgggtaat aggatgtatt tcttggggag ctttaatagt aggttttcct
    14941 acatcattat cagcagtatg ggctccagca ggtgaaccac atatacaaaa aattataatt
    15001 gtagtcatga tagttgggct tacaattata aacttattag gtgtatctct atcaaaaatt
    15061 gtacaaaatg ttataactgt aggtaaacta attccattaa tactatttat aggaataggt
    15121 atatttttta taaaaggagt taattttact tcttcaacaa tggtacctcc aggagctgga
    15181 gcaacagagt ttggagcagc agcactttta atgttttatt catttacagg atttgaatct
    15241 atagcagttg cagcagaaga tatggagaat ccacaaaaaa atataccaat agcaattata
    15301 agtgtaatag taattgcatc aataatatat atattaaatc aagttgtatg tgttggtata
    15361 ctaggagatt cgttatctag tacatctaca ccagtggcag atgctgcaag aatatgcttt
    15421 ggaaatatgg gagctggatt ggttaccttt ggaaccttgg tttctgttgg tggaatttgt
    15481 atgtgtggtg cttttgtaaa tccaagaagc tgtgtagctt tagctgatga taaaatgtta
    15541 ccgagaatat ttgcaagaaa agataaaaaa ggtacaccat atgtagcgat aatagctact
    15601 atgctaatca ctataccaat agctctatct ggaagttttg ctgaattagc agcaataagt
    15661 gcagttgcta gattcataca atacatacca acatctttat ccgtattagt gtttagaaag
    15721 aaaagaccag aattagtagg tacttttaaa actccttttg gagcagtgat tcctctaatt
    15781 gctgtatgtg ttggaacatg gttattattc caagcatcta tgcatcaatt aattatggga
    15841 ttaggagctt tggcaattgg agtaccatta tactttataa tgaagtctta taatagaaaa
    15901 gtctatgatg aaaatttaaa gaaaatagtt taattatgtt ataacaattt attgagttaa
    15961 aattagacat tggcataaaa ttaaatacaa ataagtatct acaaggctat attaaaatat
    16021 tattaatttt ttattttaat atagccttat attgttatca ataaatgaaa aatattgtaa
    16081 caatagaaga acaatagtat tatgtttata gacaaaaaac ttattaggag gtaaatttat
    16141 gccaacaata acattaaaaa atggtgtaga cgtacttatt agagaaggtg taagagaaga
    16201 tgctcaaagc attatagatt tttataatga agtgggtgga gaaactcatt ttctgtcatt
    16261 tggaaaggat gaatataaaa tatctttgga ggaacaagaa aatgctatag aatcagcaaa
    16321 agcatccgat aattctgtta aactgattgc atttatagat ggtgaaatag ttgggattgc
    16381 aacgattgat tctaatcaaa aagcaaaagg aaagcatgtt ggagtattag gaattgttgt
    16441 aaaagaaaaa tattggggaa ttggattggg taaaaggctt atgttagacc ttatagaatg
    16501 gtgtaaatca aatggaataa ccaagaagat aactcttgtc actaatgaag aaaattataa
    16561 tgctatagga ttatacaaaa aagttggatt tgaagtagaa agcatactaa agaaagaatg
    16621 ttattataat ggtgtttata ctgatttaat aggaatgtca cttttattgg gaatataatt
    16681 agtgtacatt ttatctcgaa aaaagtatat taagtatggt ataattaaaa aagaatataa
    16741 cttaatataa ttttggagga cgaattatga aaaatctgtg taaaatatca gatgattatt
    16801 taaacagcaa gcttaagtat ttaaagttat tatcaaaaca atatccaagt atatcaaaag
    16861 caagtacaga aataataaat ttagaggcta tattaaatct tccaaaggga acagagcatt
    16921 ttataacaga tgtacatggt gaatatgaac catttgtaca tgtattaaaa aatggttctg
    16981 gtgtaataaa gagaaaaata gaagaattgt tttcaaatac aataagagac agcgaaaaaa
    17041 aaatgttagc aactcttgta tattatcctg aacaaaagtt agacctaata attaagcaag
    17101 aggaaaatat agatgatttt tatagaataa atatttatag acttatagaa ctttgtaaat
    17161 atgcttctag caaatatact aggtctaaag ttagaaaact gttaccagaa aattttaaat
    17221 acataataga agaacttttg catgagcatg ttaaaagtga acataaagaa gagtattata
    17281 aaagtatagt tgaaacaata gttgacatag gaatagctaa ggagtttata attgctattt
    17341 ctacagttat acaaaaattg gttgtagata gacttcatgt aataggagat atttatgata
    17401 gaggtccaag accagatata attgtcgata agcttattga acatcattgt gtagatattc
    17461 aatggggaaa tcatgatata ttgtggatgg gtgcagcctc aggtgaaaaa acttgtatag
    17521 caaatgcact gaggatatca gctagatatg cgaatttaga cattgtagaa gacatatatg
    17581 gaataaatct attgccttta gccacttttg ctatagaaat gtataaagat gacccttgta
    17641 aagaatttat tccaaaggtt aatgaccaaa gtgtaacaac aacagaaaag tctttaatgg
    17701 caaaaatgca caaagcaata agtataattc aatttaagct tgaaggtgag gttatcagac
    17761 gaagacctga atttgaaatg gaacatagac tcttgcttaa tatgataaac tatgatgaag
    17821 gtacgattaa tttaaaaggt aaaacatata aattaaaaga tacttattta cctacaatag
    17881 acaaaaaaga cccatataaa ttaactatgg aagaaagaaa tgttattgat aaattagtat
    17941 cttcatttag aggtagtgaa aaattacaaa aacatgtttc atttttgttt tctaaaggaa
    18001 gtatatattt aaaggctaac tcaaatttac tgattcatgg atgtgtaccg ttaaatgaag
    18061 atggaagctt tatgtctatg aatataatgg gaaaagagta taaaggtaag gctcttatgg
    18121 ataagatgga gtctctagca agagaaggat ttttctttaa agataaggca gaagaaaaac
    18181 tgtatggcat ggatattatg tggtatttat ggactgggaa atgttcatca ttatttggta
    18241 aagatgatat gactacattt gaaagatact ttatagctga aaaagagact cataaagaaa
    18301 ataagaaccc atattttaaa cttagagaaa atgagatggc ttgtaaaaga ttatttgaag
    18361 aatttgattt agaacttgat gaatctcata taataaatgg tcatgttcct gtggagagta
    18421 aaaatggaga gagcccaata aaagctaatg gtaaaattct cgttatagat ggtggttttt
    18481 ctagggctta ccaaaaaact actggtatag ctggatacac tttgatatac aattctagaa
    18541 ctttgcaatt agtatcgcat gaaccattta attctgctga agaagccatt gcaaatgaaa
    18601 gtgatatctt atcgacaact gttgtagtag agcataaggc aaagagaaaa atggtgagag
    18661 atactgatga aggagtaaag atacaagagg aaatagaaga tttaaaacta cttttaatgg
    18721 cttataagaa agggctaata aaagaaatgt agatgttata gaggcacttc atgattgaag
    18781 tgtctttttg ttaatactta ttaaatatat tataaagatt aataatagta gtttatatta
    18841 tacttactaa gtgaatccaa gataaatggg ttcacttttt ttatttataa acattattaa
    18901 aaaaatatag atgttttggt tatattcctt gtcctttata aatagaatta tataaacaaa
    18961 ggaggaggac aagagatgaa taaactttct gatgaaataa taaactctct ttctacaact
    19021 ataagagaaa aggtagaaaa agtctcaaac aataatctga acatagaaga aattaggtta
    19081 cgctcacaaa aaccattgat actaaatgca aactctaaag attattttta caatcaaaaa
    19141 actatgacac ttgatttaaa tcaacaaaac tcatatgtag taacaagaga agatgtagag
    19201 caaacttttc aaataatatg taaatattca atacattcat ttatggatga cataaaaaaa
    19261 ggattcataa ctttgagagg aggtcataga gtagggttag ttggaaaagc aatagtagaa
    19321 gatggacaag tcaaaaatat aaagcatata tcatctttaa atataagggt atcaagggaa
    19381 attattggat gctcggataa gattttaagt catatcataa agggaaaaaa tcagattaat
    19441 aatactttga taatatcacc acctcaatgt ggaaaaacaa ctttaataag agatatagta
    19501 agaaatttaa gtaatggtaa tgaagattat ggatttaaag gtttaaaagt ggctttagta
    19561 gatgagcgta atgagatagc aggagcttat ctaggtgttc cacaaatgga tgtgggaata
    19621 aggactgata taatagaaac ttgcccaaaa gacttgggta ttacaatgct tttaaggtct
    19681 atgtcaccaa atgttattgt gacagatgaa attggaagtg aaaaagaaat aaaggcatta
    19741 tacacagcat taaatggagg tataggatta ataactactg tgcatggaga ttcaatagag
    19801 gatatacaaa atagaaaaga attaaataga cttctggata aagagttatt taaaaaggtt
    19861 ataattcttt ctgcaaaaag aggagcagga acaattgaaa aaatttatga tttagaagaa
    19921 aagagatggt attttgcaaa ttaaaataat tattatagct ttcttgatag gaagtagtta
    19981 tttgataggt gaacaaatat acaaaactta tactcgtaga cataaacaat taaacgattt
    20041 aataagagtt ttagaaattt tgaggatgga tttatctttt ggactttata cattagaaga
    20101 aatctttaat aggataggtg gaaataaaga gttttgtttt tggaaatttt tctatcaaat
    20161 atcagaagga cttcacaatg aacaaagtaa aactttggaa ataataatat cagaaaatat
    20221 tgatgtctta agtaaagaaa cttatctagg caataaagaa attgaggaac tgaaaaatct
    20281 aatacttact ttagggaaaa gcgatataga gtcacaacaa agaatgatag atttatctat
    20341 agaaaatttg aaaaaacaaa cctatgagac aaaggaagat ataaacaaaa aaggcgtatt
    20401 gtataaaaaa ttagtgacat tcataggtat aggtatatgt attatattga tttaatatgg
    20461 ggaggtttat tatggaaata tcattgatat taaaggttgc aggtgtcggt attctaatat
    20521 cagtattgaa tatgatattg gaaaaaacag atagaaaaga ttgggcaggt cttactacat
    20581 tagcaggtgt aataatcgta ttgggtatgg taataacaga aataagtgac ttgtttaata
    20641 ctgtaagaac aatgtttcaa ctttactaaa gaggagggag taatttggaa ataatgcaat
    20701 taataggaat tgcaatcatt tcaactacac tctgtttagt aattaaaaaa gatagaccag
    20761 agatagcaaa tttcatagct ataataactg gagtaataat actattgtca gttatgttta
    20821 agctaaattt tatagtagat agtatacaag atttggctaa caaggctaac atcccgacta
    20881 tgtatatatc attaataata aaattaattg ggatagcata cttaatggaa tttgcgatac
    20941 aactttgtaa agattgtggg gaaggaaaca ttgcttcaaa actagaattt ggaggtaaaa
    21001 taatagttat gtcaatgtct ttccctatac ttttgtccat tgtagaaatg gtggtgaata
    21061 taattccata gatgtgtatc ttggaatgaa tataagtata ttagagagct tttgttgtat
    21121 tgaggtttat agagtgaaga gaggcatggt tgcttatgaa aaaaagattt ttaccaatga
    21181 ttataggttt tttatttact ttcttttttg taaatatctt tgctattatg atatttgcta
    21241 atgaagtacc aagtagtgaa gataaagaat atggtgaaac aaaaaatagc atagataagt
    21301 atatagatgg tcaattagac aagctagata taaatgagat tcaagactat ataaataaag
    21361 aaatagttat taatgatgtt aatttaaaat catttgtaaa agatttaatt agtggagaaa
    21421 aaaatatctt agatttattc aataaagatg gattgaagat attgatgttt gatgaattta
    21481 aagcaagttt aaaggtagta gcagtaattt tggtactggc tctgttatca tctattttaa
    21541 agagtctgga aaactctttt tcatcaggtg cagtaagtca aatagcaaca tatataatat
    21601 ttatcacaat ggtatcactt acacttattg gttttaaaga tgtattacag atttgctatg
    21661 atgcaataga ccatactgta ggtcttatgc aagttataat gccaatatta ataacatttt
    21721 tacttttaat tggattccca ataacgtcga ctactttgaa tcctatcttc ataggaggag
    21781 taacatttat aaatgtattt tttaaaaatt ttctatttgt atctattact gttgcatttg
    21841 gaattttaat aataaacaat ttatcaaaaa atataaggct aaagagattt ttctcctttg
    21901 taaaacaaat aaattatgtt tctattggag ctatgtttac tgtttactta ggtcttgtat
    21961 ccatacaagg attgtatgta accagttttg ataaattcag tgtaaagact gctaaatttg
    22021 ctataggtaa ttttattcct gttgtaggtg gatttgtatc tgactctgtg gatattttat
    22081 tatcttcatc tcagcttata aaaaatatat ttggaggaat agggcttatc ttacttgttg
    22141 gaatttgctt acttccagta ataaaaattt tatcagtaat agtagtgtac aaattagcag
    22201 caataattgt agagcctgtt ggagaggatg gaatatctaa ttttttaaat gaagtggcaa
    22261 atttaatgat aataatgcta gcatcagtaa ttgctataac agtaatgttc tttgtaactg
    22321 tagctatctt gacctcgata agtgtcgtaa gtcaagggta atttatatat cagtgaaaaa
    22381 taattacatt taatctaatg tttttagaga ggaggatgct atgttagagg gcataaaggc
    22441 atggatagtt agtgttttga taggagcatt tatagtaaat atagtagata tgattttacc
    22501 aagttctaag ataaaacctt atgtcaacct agttttaaac tttatgtttg tatttattgt
    22561 aataactcca gtagtaggat ttttttcaaa agatatgagt ttagaagata gaatattaaa
    22621 atctatggga aactacaaca agcagtatgt agatagtaca aatgctttgg caaaagagac
    22681 tggaaataat agtctatcca agggatatga ggatgggtta aaagaagtac ttaaattaaa
    22741 acttgatgaa tatggttatg atttagaaga tatagagctt aatggggcaa atataaataa
    22801 tataaaaata aaagaaaaga ataatagtgc aaaaagtaat aacagttcca atgaagaaaa
    22861 taaaaataat agtactaaaa gagaggaaga aaacataaac tctaatgaca aagaaaattc
    22921 taaacaagtc ttcaaaaaag gtacagagta tgggttgaac ctaaatgaag aaaaattaaa
    22981 aaacgactta ataaaggtgc tggatgtttc tatagaagat atacaaattg ataaatagga
    23041 gttgggagaa tgttgaaaaa cttaaatgac aaagataaga gaaaggtata ttcactaata
    23101 actatagcag gaatatgtgt ggtttcatta gtattattat cttgttttcc tagtagcaaa
    23161 agcgataaac aagttggaaa aacagagact aataaaaatg ctgaaaagca agtcactaaa
    23221 gaacaagaaa aagatgattt agagtcaaaa ttaacagcaa tactatctaa aattgatggt
    23281 gcaggagacg ttgatgtaat ggttacattt gaatcaagtg aagaaataca acctgctttt
    23341 aattcaaata atacaacaga aacaacagag gaaaaagatg cacaaggtgg agaaagaaca
    23401 gttacgactt ctagtgaaaa taaaacaatg ataacttcaa attcaagtga ccctgtagtt
    23461 ataaaaacta cagagccaaa gataaaggga gtgatagtgg tagcaagtgg agcaagtgac
    23521 ccaagtgtta aagagacact ttatagtgca gtacaaacat cattacaagt agctggtcat
    23581 caagtagaaa tatattctaa ataaatacat ataaccgggg ggataaatga atgaagttta
    23641 attataaggg aagaggattt gtaataataa ctttaactgc aatgttagtg gtagtaggaa
    23701 cagtgaatta tcaactaagt aagaaatctt tattagaaac atcaaaagag tttaaggcat
    23761 atgaagaagc acagttgcaa aaaaatactg atgatagtta tagtagtaag acagaggatt
    23821 ctagtaatgt agataaacaa ggtggtaagg aaagtgctga tattgatata gtcgatagca
    23881 aagctagtaa agtaaaagaa aaggcaactg agacaagtaa ggaaataaaa gctcaattat
    23941 catcagagaa aaatatgaaa aaggcatctt atattttaga tatgaaaatg aatagagaaa
    24001 aacaaagaaa tgagttagtt caagatttaa atgaaatgat aaataatcca tctacaacag
    24061 aagaatctag aaaagaagct tctaatatga aattaaatat agttaaaatt caagaaaaag
    24121 aacttcaaat agaaaacctt ttgagtacaa aaggatatga agaagcgtta gtttatataa
    24181 gcgataacaa agttaatgta gttgtaaatg aagctaaatt agaaaagaaa gatgcagcaa
    24241 aaatatttga tttagttgca gaacaagcca atgtgaagta tgaaaatatt aaacttacaa
    24301 ataataatag taataagtaa agtataaacc tcagaattaa ctgaggttat tttcttgcaa
    24361 agtagacttg tatttggtat tattatactt ataaaaatag ttccttaaaa tcaggaggta
    24421 agttttaata tggaagataa taaatttgga caagtaaaaa tatctaatga tgtaatagct
    24481 acaatagctg gtttagcagc attagaagtt gaaggcatag aaactacagc aacattaaca
    24541 gataagttgt taaaaaataa tggagtaaaa atacaaatcg aagaagagga tgttaattta
    24601 gatgtaatgg ttacgataaa gtatggaatg tcaataccag atacagcttt taaagttcaa
    24661 gaaaatgtaa aaaatactgt tgagacaatg acaggactga aggtttctca agtaaatata
    24721 cacattcaag gaatcagctt taagaaggat aaagttgata aagaagaagc aaaagcaact
    24781 aagaaaaatt aatattagcc ctctgaaaag tcagagggtt ttttgctggt aattgatttt
    24841 atatggataa ttaaacttaa aggagaattt tgattgatga aaaaagatag ggcacaaaag
    24901 agtacaacaa gagaatatat aatgaaactt atataccaaa taaatattaa taaagaagat
    24961 tttgaaactt tagaagataa agtagataat tttttaaaag ataattcaga acatattata
    25021 aatagatata aagaacttgc acttcaatac tcaaaaaata caaatttaaa gttagaagat
    25081 actgaaattg aagatgttat agacaaaaaa tatataaata cagtatgcaa agcattgaaa
    25141 gaaaatcatg acaaaataga tgagttaata aataagcatg ctaaaaactg gacagtagat
    25201 agaatgccaa aggtagatgt ttctatactt agattgtctg tgtgtgaaat actttattta
    25261 gacactccta ataaagtatc aataaatgaa gcagtagaac ttgcaaaaat atattgtgat
    25321 gataagtctc ctaaatttat aaatggtata ttgggaagtg ttgttgatga aattgggaaa
    25381 taatataata attggaattg atactagctg ctatactact tctatagcag ctatctcttt
    25441 agataagaaa gttatattca atgaaaaaat aatgttagaa gtaagggata attcaaaagg
    25501 tttaaggcaa agtgaagctg tatttcaaca tatcaataat ttagggattc ttagtgatag
    25561 gataaaatct tttaaagata agtttaatgt agaaggagtt tgctcatcaa aaaaaccgag
    25621 acctgttgaa aactcatata tgcctgtatt caatgtaggt cataattttg gaaaattatt
    25681 gtctagtata tatggttgta gattttatga gactactcat caagagaatc atattgaagc
    25741 aagtttatta aatagtaaat taaaaaataa taataaattt atttctgttc atatgtctgg
    25801 tggtactaca gagatacttt taacaagcaa acaagatagt catcacaatg tatgtgatac
    25861 taatttaggt aaaattgcca aaataagtat taaaaaagat gataaaagta agttatacaa
    25921 taattttgga tataatatag atataattgg aggaagtaaa gatattagct ttggtcaact
    25981 tatagataga gtaggaatta agcttggata taaatttcct tcaggaaagt atttggatga
    26041 aaatgcttta aattgtaatc ttaaaataga aagtggtctg aaaacttctg taagagatgg
    26101 gtatatgaat ttatcaggat tagaaaatca ggtaaataag attataaatg ataatggaga
    26161 taatactaat caaaaagaat atatatctaa attagtatta gattcagtag ttagaaatat
    26221 gtttaaatct ctagtgtatt tatgtgaaac ttataatgta aatgaagtag tatttgctgg
    26281 tggagtttct gcaagtaagt atattcttag agaattaagc atgaagttaa gaaaaaagca
    26341 tatagaagct tattttacag aaccacaata ttcaactgat aatgctgtcg ggtgtgctat
    26401 aataggattg aataactttt taggagaaag agtatgaaac taagagcttt agatataagt
    26461 gaagcaaact catatattaa aagaatttta ataaacgacc caatactttc taatcttaaa
    26521 gttaaaggag aaatttctaa ttttaaggtt catagtagtg ggaatgtata tttatcactt
    26581 aaagatgaaa catcaaagtt aaactgtgta atttttaaaa gtaattttaa tcgcaattta
    26641 aaattagata atggtgtaaa aattatagct aatggatata tatcagtcta tgaaagagat
    26701 ggtgcgtatc aattatacat taatgaaatt gaaatagagg gaataggaaa tttgcacata
    26761 gagtttaata gattaaagga aaaacttaat aaagaaggat tatttgaccc taaatacaag
    26821 atacctatac ctaaaatgcc aaactcaatt ggcgttataa catctccaac aggtgctgtt
    26881 ataagagata taataaatgt aataaaaaga agatatccga aagttaatat aaagctttat
    26941 ccagtaacgg ttcaaggaga taaatcagct gaagaaatct gtgaagcaat tagatttttc
    27001 aatcatatga agaatgttga tacacttata gttggtagag gtgggggttc aatagaagaa
    27061 ctttggtctt ttaatgatga aatggtagca agagaggttt ttaattctca aattccgata
    27121 atatcagcag ttgggcatga aacggatttt actatttgtg actttgtgtc tgatatgaga
    27181 gccccaacgc catcagcagc agctgagatt gctactccat cattggatga tataaactat
    27241 aaacttggaa acataaaaag taggatgagt aagtctctta caaatcaaat agagctagac
    27301 caatataggt tagaaacagt atttaataag ataaataact atttagattc gtacacaata
    27361 aaagataaag ttatacaatt agacaaaata tatgataaaa taatttttgg aatagaaaat
    27421 aatttaaaat tagaagatga aaaattagta aaaattggag cattactcca taatttaagt
    27481 ccattagcta ctatggatag aggttatagt ataactcaaa aaaatggaaa agtaataaat
    27541 agtataaaag gattaaaaat aaaggatagt atagatatag tattaaaaga tggaaattta
    27601 gaatgtatga tagataaaat tgaaaataaa gagggatagt atgaatttaa cctacgaaga
    27661 agcttataaa agattagaaa gtattttaag tgaattagaa tctaaaaatg ctagcttgga
    27721 tgaatcttta agcctatatg aagaaggtat aagcctttat aaacattgta ataagctttt
    27781 agatgatgct aaattgaaaa taagtaaatt taatcaattg ggaatagaag aagactttaa
    27841 aatagaggag gaataaaatt ggaatttaaa caatgtctaa aagaaaaagc aagttttgta
    27901 gaaaaagtac ttaaagaata tatgcctaaa gaagaagggt atcaaaaaac tgttattgaa
    27961 gctatgaact atagcttaag tgctggaggt aaaagattaa gaccaatact tacattggag
    28021 gcttgtaaaa tagttggagg taatgaagat gaagctattc cttttgctat tgcaattgaa
    28081 atgatacata catattcact aatacatgat gatttgccag ctcttgataa tgatgattta
    28141 agaagaggaa gaccaacaaa tcataaagta tatggagaag ctatggggat tttagcagga
    28201 gatgctttgt taaactatgc ttttgaagta atgcttgcag gctcaatcaa taaagaaaat
    28261 ccagaaaagt atctaaaagc tataaatgaa attgccaaag gtgctggtat atatggaatg
    28321 ataggtggtc aagtagtaga tgtagaaagc gaaaataaac aaattgaaaa agaaaaatta
    28381 gattatatac atatgaataa aactgctgca atgatggtag gctgtatgag agcaggagct
    28441 actataggtg gagcaaattc tgaacaaatg gaagaaataa ctaaatatgc aaaaaatatc
    28501 ggattatcat tccagatagt agatgatata ctagacatag taggagatga agctaagtta
    28561 ggtaaaaagg ttggaagtga tatagaaaat cataagtcaa catacccatc tcttttaggt
    28621 ttagataaat ctaaagaaat tgcacataat ttgattgatg aagcaaagaa aagtatagaa
    28681 aaattatctg atgatgtaga ttttttaaag ggattggctg aatatataat agatagagaa
    28741 tactaaaata tacagctaaa atcgaggagg gaaaaatgga ttttttttcg gagattttta
    28801 acaatggggc tttgggaata agtctgattg cttgtttctt agcacaattt ataaaaatat
    28861 ttactggtaa ggaaaaaaga attgagttat caagaatact tatttcagga ggtatgccta
    28921 gttcccatag ttcttttgtt acaagtttag ctacagtggt aggtattgaa aaagggttta
    28981 attctactga ttttgctata attaccgtgc ttgccttaat tataatgtat gatgcagcag
    29041 gtgttagacg ggctgttggt aaacaagcta ctatattaaa tcaaatggtg gcagatatac
    29101 agcatggaaa gcatatagag cagaagaaat taaaagaatt aataggtcat acaccactag
    29161 aagtttggtt tggagcttta cttggaatag taacagcttt aatattgatg taaattgaaa
    29221 atttacagaa taaaggtgag gataatatgt ataaatattt agataaagta aattctccaa
    29281 aggatataaa aaatatgagt atagaagaaa tggatttact tgcaaaggat ataagaaagt
    29341 tcttagtaaa atctgtttca aagacaggag gacacttagc ttctaatcta ggagtggttg
    29401 agttaacatt agcacttcat aaagtatttg atagccctaa agataagatt gtatgggatg
    29461 tagggcatca atcttatgtt cataaaatag ttactggaag aaaagattgt tttgtatctt
    29521 tgagacagtt taatggacta agtggttttc caaaggagaa tgaaagtcct catgatattt
    29581 ttgatacagg acatagcagt acatctattt ctatagctac aggtattgcc tgtgctaggg
    29641 atataaaaaa agaaaactat agtgttatat ctgtgatagg agatggttct ataacaggag
    29701 gtatggcact tgaagcttta aatcaattag gatatataga taccaatatg atagtaatcc
    29761 ttaatgataa tgagatgtcc atagataaaa atgttggagg aatgtctaaa tatctgtcaa
    29821 gtattataag aaactcaaca gttgagaaaa tgacagatga agttgataaa attttaaatg
    29881 ttacacaaac aggtgaaatt ttatctaaga ctgcacatag atttaaagat aaactaatgt
    29941 atagcttttc tcctcaggac tgttcatttt ttgattcatt aggtataaga tattatggac
    30001 ctatagatgg ccataatact aaagaactaa tagatatatt gagaaaagct aaacacaaaa
    30061 aagggcctgt tcttttacat gtaattacga aaaaaggaaa agggtacaga tttgcagaag
    30121 aacaacctga taaatatcat ggagtatcaa agtttgatat aaagacaggt gttacatctg
    30181 caaaagttaa gtctatgtca attagtgttg gagaaaaact tgttgatatg gctaatagta
    30241 atgaaaatat agtagcaata acagctgcaa tgccatctgg tacagggtta aacctgtttg
    30301 aaagtgcata tccaaaaaga tattatgatg ttggtatagc tgaacaacat gcaacaggat
    30361 ttgcagcagg tcttgcaaaa aatggtatga aaccttactt tgctgtgtac tcatcatttt
    30421 tgcaaagggc atatgaccaa gttattcatg atgtatgcat aacaaaaaag ccagttactt
    30481 ttcttataga tagagctgga ttagttggaa atgatggaga aactcatcat ggtatgtttg
    30541 atttaagtta cttaaattct attccaaata ttgtagtaat ggctccaaaa gacacaagag
    30601 agatggagct tatgatggat ttgtcattaa aattagattg tccactagca attagatacc
    30661 caagaggaag tagttattac ctagataagg gagagtatgg agagattgta ctgggtaaat
    30721 atgaggtatt agatgacggt caagatacag tcatactttg tattggaagt atggtaaaac
    30781 atgctttaga ggctaaagaa atattatcaa gagaaggaat aaatccgaca atagttaatg
    30841 ctagattctt aaagccaatt gatgaaggta tgttaaaagc attattaaaa aatcataaaa
    30901 atgtagttac tatagaggat aatattgtaa ctggaggatt tggaagtaga ataaataagt
    30961 ttattataga taatgaatat aacgtaaata tacttaatat agcaatacca gaagaatttg
    31021 taaaacatgg caatatagat gaattatatg actttgtagg attatcgcca aaaagtattg
    31081 ctgataagat aaggaaatta gttattgagt aaaaatctaa tgtagatatt gtaaattaaa
    31141 atttatataa aatatagaat ttatcaatta gaataaatat caagtgtgtt acttcaagct
    31201 actttagtta tcattaaagt agcttttaac agaaaggtaa ttgtatgaaa aaaagaatag
    31261 atttattatt agtagaacaa gggtactttg aaagtagaga aagagccaaa aaagcaataa
    31321 tggctggatt ggtttttgtt gataatcaaa ggtgtgataa ggctggtaca gaagtaaaag
    31381 aagattgtag tatagaagta aaaggaaatc caataccata tgtcagtaga ggtggtttaa
    31441 agcttgaaaa agcaatgaaa aactttgatt tgactattga tggaaaggta tgtatggata
    31501 taggggcatc cacaggtggt tttacagatt gtatgctcaa aaatggagca ataaaagtat
    31561 tttctataga tgttggttat ggtcaacttg catggaaatt gagacaagat gatagggttg
    31621 tgtgtatgga aagaaccaat ataagaaatg tgacaataga agatacaaag cagtttgctg
    31681 attttgcgtc aattgatgtg tcttttatat cgttaaagtt agtacttcca aaggcaaagg
    31741 agttagtacg tcatgatggg gaagttgtcg ctttaattaa acctcaattt gaagcaggaa
    31801 gagaaaaagt aggtaaaaaa ggagtagtta gagaaaaatc tacacatata gaagttataa
    31861 aaatgatttc tgatttctca gtcgaaaatg gatttgagat tttagggtta gatttttctc
    31921 ctattaaagg tcctgaaggt aatatagaat atctaattca tttgagaaat ggaaatgaag
    31981 gatatgaatt tgatggtgag acatacaata acaaaatagt agaagttgtt gaagcttctc
    32041 ataatttaga caaataggtt aaaagggggc ttagatttga tcctcgaatt atatatgaaa
    32101 aattgtgcct tagttgaaga actaaggttg aatattgata aaaacttaaa tatacttaca
    32161 ggtgaaactg gttcaggaaa atctataata atagatgcac ttggactttg tttaggtgat
    32221 aaatatgata ggtctttttt aagaaaagga acagataagg gacttgttga ggctgtattt
    32281 ttttcagaca atagatatct taaaaaaata ttagaagaaa atgatataag tatggaagat
    32341 gataatttat tggtaataac taggttgata tactcagatg gtaagagtac tgctagagta
    32401 aatggaagga ctgttaaagt gtctcttctt aaagaaattg catctacact tatagatata
    32461 catggtcaac atcaaaatca agctttgttt aataaagata ctcatttaaa atttctagac
    32521 ctttttggag aaaatgaatt ggaagagttt aaaattgctt ataaaaatgt gtaccataag
    32581 tatagtgaag taaaaaaagc tttaaattgc ttgacagaaa ataaagatga gatgcaaatt
    32641 caacgagaaa tagatttatt aagatttcaa ataaatgaaa ttgaagctgc aaatctaaat
    32701 aagaatgaat atgaagattt attaaaacaa agagaagttt atagaaatag tgaaaagata
    32761 tataataatc taaattcgag ttatagcaag ttacataatg gtgagtataa tgttattgac
    32821 ctaataggtc ttgcatctaa ggaacttaat gacatatcta aatatgacag tgttttaagt
    32881 gaatatagtg atactgtaga aagaatcatg tatgagttac aagacatatc tggtgagata
    32941 agaaattaca aagataatat agactttgaa ccttatgagc tagagcagat tgagcttaga
    33001 atcgacgaga ttaataactt aagaagaaaa tatggagaca gtatagatga tatatttgag
    33061 tattatggaa aaattaaaga tagattagat gaaatattaa acagagatga aagagttgaa
    33121 cagttaagaa gcaaactgat gaatatagaa gaagatttaa aaataaaagc cagtaaattg
    33181 actaaagcaa gaatagaagt agcaactact ttagaaaaaa tacttcttga tgaattaaaa
    33241 agcttaaata tgaaaaatgt aatgttcaag gttaattttg aaaaaggtcc atttacttta
    33301 gatggagtag atgatattga atttatgata tcttttaact taggagaaga tattaagcct
    33361 atatataaag ttgcatcagg tggtgagatg tccagattta tgttagcgtt taaaaccata
    33421 ttggctgata tagatgatat tgatacatta gtgtttgacg agatagatac tggaataagt
    33481 gggatagcag cacagatagt tggtgagaaa ttgagtgata tagcaaagaa aaaacagata
    33541 atatgtataa ctcatttacc tcaaattgct gcaaatgcag acactcatta ttgtatagag
    33601 aaagatactt caaataatag gacgtttacc aatgttagta agttaaatga atctcaacga
    33661 aaaaatgaaa ttgccagact tatagcaggt aacaatataa cagaaaaaac tattgaacat
    33721 gcaagtgaaa ttattgagtt ggctaaaaaa tgttagtgaa aaacaagcat tttaataggt
    33781 gtaaagaatt tttatagaaa tgctttacat ctatttttta tgatgaaatt attttaaaat
    33841 atctagtgcc tatattgaag aaaagtaggt ttgaaaatgg aatgaacttt gtataaattt
    33901 gtaactttga aatttctaaa tgcttaagta taatattatt tattaaggta gtagtgaggg
    33961 gaggcataaa atgaataaaa aagatactat gcacttaatt tttataattg taatttttat
    34021 tttattatgg tatattgtgg tagcagtaag tgagattaat aaaaatattg aaagttgtag
    34081 taacaaatta gattatttgt cacaagagct tatgagtact aagtcggata ttagtaatac
    34141 tataaatgaa gaaatgtcaa aaagctatat aacaaaaagt attgacttaa aagtgaaaaa
    34201 aatcgagaaa aaagaatgta ttattgatat agatgttcaa ttaagtaaac ttggaaaaaa
    34261 tggaaaagta ttttttatgt ataaagaaga tagtgataaa tggaatgaaa ctgagatgac
    34321 aaaacatgga gaattatcat atgcatgtga aattaagata aatacaggaa gtgaatatga
    34381 ctataaagta gttacaagtg gagctatatc tgaaagttct gatgtgcaaa aattgactaa
    34441 atctgattat atgcctgaac aacccatatt taattctggg ataagagata atagagaata
    34501 ctttattgaa atagtagaaa atagtaatct tttcaatcat gagagtgaaa agtcaaaaaa
    34561 taaagtttat gataatatta gattagaaaa agtagatatt attgtaaatg aaggaaaaaa
    34621 agacactata tacaaagcca aattagctga aggcttagat gatggcaaaa ctaataattc
    34681 aaatagaaat caagtgaatt atgaagtaag ttttcctaaa agggatattg atgacataat
    34741 ttatattaaa gctaaactta catacaataa tggagtagaa tatacaaagg atataactga
    34801 agatataact atgggattac aagatttaga aaaataaata catatttaaa taaatattca
    34861 aatagatttg ttcaataaaa tagagtataa ataaaactgt agtagtttta cttatactct
    34921 attaaaaaat tataatttta attccatata tctagcccct tcaattggat tataagtata
    34981 aggttctata tcataaaaac caaacttttc gtataatcct tgtgcacttt tcatgcttgg
    35041 aagagtatct aatctcatgt gtgtatatcc aaatttttta gcttcttcaa tgatttcttc
    35101 caatagtatt tttcctattt ttaatcctct aaattgattt cttacatata atctttttaa
    35161 ttcacatatt ttaccttcaa gtttttttaa agcaacacaa cctgccaaat tttcatcaac
    35221 aaatgccaat atcaatgagc ctgaaggttt tttatatttt cctggaagtg tttttaattc
    35281 attattaaag tcttgaaaac ataagtctat atttagagaa tttgaatatt cagtaaatag
    35341 aagttttacg ttttcaaggt tttctaaatc tttttcttca acaaattgta aagttatatt
    35401 ttgagccatt ttatccgcca ttatatacac atgtttatat aatgacttca cctccttgat
    35461 atatgtatat ttttcttaat atcaattaga ttttaatacc attacttttt caccaccata
    35521 gtcaagctct ccattaaact caaatccaaa atctttataa agcttaatag ccattttatt
    35581 gtcttcgaat atactaagat atagttcatc acagttatat tcatttttaa gatgatttac
    35641 aagaaaatct aatgatgctt ttccatatcc tttaccttga tattttgaat caatcataaa
    35701 tctatcaagc caaactctat catcttctaa acgaccatac atagcaaatc ctattaaaga
    35761 attttcatca tatattccaa caggtaccca agctgttata aatttagatt cagcaataga
    35821 aagtgcattg ctttctatat aatctaactg acttttatct acagacaaac taactaaatc
    35881 atgccaatta tttatgtctg caattcttac atttaatttc aagatattac cgcccttcaa
    35941 actttttgtt acaatctaat actatcatat tatgtattaa aaatcactta ttaagatttt
    36001 aaataaactt tttaaatgaa taaattctca ggaaaaagga attataaata cataataata
    36061 cagcatagga gtagatggat atatgaacaa aataaataaa aatttcaaaa atatttggat
    36121 aatattagga gctgtatcga tttttaccat ggttataatt tttaataaaa attgtaatgt
    36181 taataaagag actcaaatag aagcttttac aattaagaat catgataaaa aatttgtata
    36241 tcctatggga aatataattg gagtaaaagc aaatacagat ggtgtattgg tcttaggata
    36301 tgaggaagag gatgtagact atattggagg catacaaatc ggtgataata tagtaaaaat
    36361 agataataaa aggataaaaa atagtcaaga tgtatcagag attttgaata agattaaaaa
    36421 aagtaaagtt gaagtgactt ttgagagaaa aaataagtat aaaacagaag taatagagac
    36481 taaaaaagaa aatggcaagt ataaacttgg attatgggta agagataaaa tatctggaat
    36541 tggaactatg actttttacg accctagtat ggaaaagttc aaagcaattg gtcatgccat
    36601 aaaagattcg gatactaatg aactattaaa gataaagcaa ggatatatat ataagccaga
    36661 acaattaaaa atagtaaaag ctagtaatga aaaagtaggt aaaataaaag gagattttaa
    36721 tgacagcaat ttaatgggta atttctcaaa taattcagag ttaggtataa gtggtaatat
    36781 tacagaaaac cataataaag agtttaatgt agcaaataaa gaaaagcaat taatagaagt
    36841 tggaagaccg caagatgtaa aaataggagg tgcagtaatt ctttttgagg ataaaaacaa
    36901 aaatataaca agctatgata taaaaataga aagtatagta tatgataaag gaaattatag
    36961 agatatggta ataaaagtag tagatgacaa gttattggaa tacacaggag gtatcgtaca
    37021 ggggatgagt ggagctccaa taatacaaaa taataaaatt attggtgcaa taactcatgt
    37081 ttttagagat aatccgaaaa aaggatatgg tatttttata gatgaaatga taaaattgta
    37141 ggtgaggcat taaaaaattt tattatttta tcaattatct aggaggaata taattttgga
    37201 gtgtcgaata tgctttagag tagataatta ggaagcaatt gtgtaaaaag tttagttttc
    37261 tgtaataaga agatgttttt taatgggggg atttttagtg gaaaaaatca aaatagtttt
    37321 agcagatgac aataaggatt tttgtcaggt attaaaagag tatttgtcta atgaagatga
    37381 tatcgatata ttaggcatag ctaaggatgg aattgaagca ttagacttag taaaaaagac
    37441 acaaccggac ttattaatac tagatgtaat aatgccacat ctagatggat taggtgtaat
    37501 tgaaaaattg aatactatgg atatacctaa aatgccaaaa ataatagtac tatcagcagt
    37561 aggtcaagat aagataactc aaagcgcaat aaatctagga gcagattact acatagtaaa
    37621 gccatttgat tttgttgtgt ttataaacag aattagagag ctagtttcta atagagttac
    37681 acaagttgag ccaaaaccta gaccagttca agagactcaa atgactagaa gtgattttgt
    37741 taagaatgta ggaaatatag agacagaaat cacaaatata atacatgaaa taggagtacc
    37801 agctcatata aaaggatatt tatatttaag agaagcaata aaaatggtta ttgataatgt
    37861 tgagctttta ggtgcagtaa caaaagagtt atatccaagt atagctaaaa aattcaatac
    37921 aacaccaagt agagttgaaa gagcaataag acatgcaata gaggttgcat ggagtagagg
    37981 aaaagttgac acaataaatc aattatttgg atatacggta cacaatacta aaggaaaacc
    38041 aactaattca gaatttatag caatgattgc tgataaatta agactagaac atagtatggt
    38101 taaataaaca agacataaaa agtaaggctt tttaattaag gcattggcta taaatgcgta
    38161 ttacaagcag cgaaacggta taaccactag ggttataccg tttcgctatt ttaataaata
    38221 taaaaatttt atttattatt tgcttactat atcaatataa taattttatt atactatgga
    38281 tatagtatgt gtctttacaa gttgtaaact gacagtggtt tattttttaa tataaatatt
    38341 gactttgatg caggtaaact ttgtattttt aagcgtatta tggaatatgt taaataaaaa
    38401 aatgatgaaa tatagtattg taaatgccaa agatgcaaaa caaacttaaa acatttattt
    38461 tattgttaag taatgctata atataatgtg attttaataa tgatagtgga ggtttaaata
    38521 tgagagtcga ggcccctata aaagtagatc gaaaaaccaa aaaacttgct aaaagagttg
    38581 aaagtgggga aatagcagtt ataaatcata tagacataga tgaagttgct gcaaactctt
    38641 tagtagaagc taaaataaaa cttgtcataa atgcggctcc ttctataagt ggtaggtatc
    38701 ccaataaagg tccagggata ttaactgaaa ataatatact aataattgat aatgttggag
    38761 aagagttatt tgaagaatta aaagaaggag aaactataga agttgtagat ggaaagatat
    38821 atagaaaagg aaaattttta ggtgcaggag aagttttaga caagtatgag gtttcacacc
    38881 aaataaaggc tgcctatgag aatttagctg tagaattgga tagatttata gataatacta
    38941 tagattatgc taaaaaagaa aaaggattta tacttggaga agtagaaatt ccaaaagtga
    39001 aaactaatta tgctaataaa catgtattga tagttgtaag aggtcaggac tacaaagaag
    39061 atttaagtac tatgctttct tatatagaag aggtaaagcc agtattggtt ggtgttgatg
    39121 gaggagcaga cgctttaatt gagtttggat atactccaga tgtgattgta ggtgatatgg
    39181 atagtgtaag tgatgaagct ttaaaaaagg ctagtgaaat agtagtacat gcttatacag
    39241 atggaagagc accaggtctt aaaagggttg aggaattagg cttagatgca gttgtatttc
    39301 ctgcaccagg aactagtgaa gatatagcta tgcttatcgc ttatgagtat aaggctgagt
    39361 taatagtagc agttggtaca cattcaaata tgattgattt tcttgaaaaa ggaagaaaag
    39421 gtatggcaag tactttttta gttagactaa aaataggttc aaagcttata gatgctaaag
    39481 gcgttaattt gttatacaga agtaaattaa aaataaagta catatgggca ttaatagcaa
    39541 cagcattatt tcctgtgttg gtagttgcat cattgtcacc aggagttcaa cagttcatac
    39601 aactaatgca attaaagttt agagtattat tacagatgta aattttagga ggataaatat
    39661 gcatattaat atgaaatatt atatagtcac tataggggct atatttatag ctttgggtat
    39721 aggcatgtta gtaggattta atttaaataa taatcaacaa ttaagtgaac aacaagcaaa
    39781 cataataaat gatttggatg ataagtttga tatcttaaaa gaaaaaaatg ataaacttga
    39841 cagtgactta gcaagtgtaa atagagatta tgaagaggca gttaatttta taaataaaaa
    39901 tgtagataag attttagctg gttcgctgaa tggtaaaagt ataggaataa tatctgctaa
    39961 tgaaaatgac gattatacaa aaaatataga agacataata aataaatcta atggaagcat
    40021 tgcatttaat ataatattaa aagaaaacat aacaaatcca gaaaagttaa aggaaatgtc
    40081 aactaaacta ggtacagatg taaaaaatgc aaatgatgca gttaattata taattgacac
    40141 tcttaaaaag gaagatgcaa gtgacatttt aacatatctt caagaactag atgtaataaa
    40201 gtttaatttt attggagata catatctaaa atatgattcc gttgtaatag ctggtggaaa
    40261 tgatgcaaaa gacagtacaa aacagtttga aaaaatagaa aaatttgtag tttcaaaact
    40321 taaatcagag aataaatatt tagtagaagt tcaaaataca ggagttaaaa cttcttatgt
    40381 agaactatat tctaaaaaca aagttgcaac tatagacaat attgatgaag gtataggaag
    40441 tatatctcta gctattcttc tacaacaagg taatatagtt ggtaattttg gtagattgga
    40501 tactgcaact tcattgttgc catctattaa atagaaataa ttttaaggag agaaaaaatg
    40561 gattcttata taagtataat aataccagct tataatgaag aaagtagaat aaaatataca
    40621 ttagaaagca tattggacat taagcaaata aatgaaataa tagttgtgga tgatggttca
    40681 attgacaata ctgctaaggt tgtatctgag ctagaaaatg aaaagattaa attttttaag
    40741 ttagataaaa atagaggtaa aggatatgct ttaaattatg gtatcaaatt agcaatgaaa
    40801 aatgcagata ttataggttt tctggatgga gatttaggaa gttctgctaa agaagttgaa
    40861 aaattaatag tacctatatt aaatggtgag gcggatgtta caatagccaa gtttcctcct
    40921 gcaaagagaa aaggaggttt gggatttgta aaaggtttag ctaaaaattc tgtgtttgag
    40981 atgactggtg ttgagttaga tgcaacttta tcaggtcaaa gaatatttaa aagagaagtt
    41041 ttagaaaagt ttgatgaaat accttttgga tatggagtag aagttggaat gaccattgat
    41101 atattaaagt atggatttaa aattaaagaa gtattagtaa atatgactca taatgaaaca
    41161 ggaagaaatt taaaaggttt tattcataga gggaaacagt attatcacat aaaaaaggtt
    41221 ttaggacaaa aaaagaaaga atggaggtaa tatcttagtg aaagattata tactttatac
    41281 cattttatta ttaactggat tatttggaac ctatgctgta attccactat ttaaaaattt
    41341 attgataaat ggaaatgtac ttagaccaaa ctataaaaaa gatatgatac cagtaagtat
    41401 gggaattgta tttttgccta tgattgtaat caatggaata atacttgctt tctttactac
    41461 agaatttaag gatttagcgt atatatttat gtttatgttt ggtatgatat ccatgttttt
    41521 tgcagggata ctagatgatg tcattggaaa tagagatgta agtggtttaa aggggcattt
    41581 taaaagttta tttaaaggaa gtcttacaac aggaggtttt aaagctttat ttggtggatt
    41641 tgtagggctt atagtttctg ttgctatatc aaaagacata attgatataa tagtaaatac
    41701 actaataata gctctatcaa ctaatttaat gaatcttttg gatttaagac caggaagggc
    41761 aataaaagca tatttattca taatggtaat tatattttta acattgacag gatttgttca
    41821 agttcttcca ttacttatag taccaaatgt acttgcatac tttaattatg atttaaaagc
    41881 aagggctatg atgggagata ctggttcaaa cgtccttgga atatctattg gaatgctcat
    41941 ttcttttggg tatccattta acattagatt aggatggtta atatttgtag ttattatgca
    42001 tatattcact gagaaatact cattaactaa gataatagaa aaaaataaac tattaaattt
    42061 tatagataaa ttgggaaggt agtattatga taagcaaaag agtggggatt gttgaatcaa
    42121 tagtaagtca aactgaaaca ctagatgata taagagtaaa tataaatgga gaaatacaaa
    42181 gggcatataa ttatcccaaa atatctggaa ctataaatat aggtgacgaa gtggttttaa
    42241 atacaacagc agtagaactg agcttaggta caggtggata ccattttgta ataactaatt
    42301 taaataatat agaatctact ttaactgaag gtggacatat aatgaaactt agatatacgc
    42361 ctcttcaaat aaaagtggat tctgttgagg aacaagaaag tatttatcat gataaatttg
    42421 cgaattttaa aggattagaa ggtctttctg ttgtagtagg gactcttcat agtatgttaa
    42481 ctccatttgc agcttcattt aaaagaaata atccaaataa aaaattagtg tatataatga
    42541 ctgatggagc atctcttcca atttatttaa gtaaaaatgt ggatacttta aaagaaaaaa
    42601 aattaataga tagtacaata actataggaa atgcgtttgg tggagattat gaatgtataa
    42661 atatatatac tgcattaatt acagcaaaag aaatactaaa agcggatgca gtatttgtca
    42721 gtatgggacc tggaattgct gggacaggaa caaaatatgg atttacaggg attgaacaag
    42781 gctctattct tgatgctgta aaaaaacttg aaggaagagc aattgcaatt ccaagaatta
    42841 gttttgctga caaacgagaa agacatcaag gtatttcaca tcatagtatg actgtattta
    42901 aagaaattgt aaatgtaaat gtagacatac caataactat atatgatgat gaaaaattga
    42961 actttataaa agagcaaatc aatttaaatg gtttagacaa aaagcataat ataatttata
    43021 tagataataa taaaacgaaa gaggatttag actattttaa tctaaaagta aagagtatgg
    43081 gaagaaatta tgaacaagat gaggcatttt tcaaagctgc aagcacagca gcatattact
    43141 taatggaggt ttaagatggt attagaagaa aaaactatta gtagtgatag ggtttataca
    43201 ggtaaagtaa ttactttaaa ggttgatact gttgaaattc cagggcaagg atatcaaaaa
    43261 agggagttag tagaagttgg tggagcagta ggaatagttg caatcacaga tgataataaa
    43321 gttgtgttag ttaagcaatt tagaaaacct atagaaaagc caatctttga aattccagct
    43381 ggtaaactag aaaaaaatga aagtccaaaa gaatgtgctg aaagagaatt aaaagaagaa
    43441 acagggtata gtgcaaaaaa tattaagcta atacataaat ttttcacttc agcaggtttt
    43501 tctaatgaga taatgtttgt atatttagca acaggtctta ctccaggaga gaataattta
    43561 gatgcagatg agtttttaga tgtctatgaa attgagcttg aagaagcata taacatggta
    43621 ttaaaaaatg acgttgaaga tgcaaaaaca tctattggat tattattagt aaaagatatg
    43681 tttaaaaatt aatatttata aaatgaataa ccctttgtcc taaagcatat tattttataa
    43741 aggacaaggg ggaattaaat tgagaagaac atatagaaaa aatgatttta gagaattaaa
    43801 tagacaaata attattatag gattgttgtt tatgatgtct attgttgttg ggtcttacat
    43861 aaataaaata ttgccaggtt ctagtaacaa tatattaaac aatataaatc ctgctgtaga
    43921 gtattataat ctaaatataa gcataaaaga tacagtgata caaaatttaa aatcagatgc
    43981 aatctttatg ggctcaatag ctctattaag tctatttgta gtaacaattc cagcagtgtt
    44041 ggtagctttt gtattaaaag ggatgtcaat tggttataca ataaatagtt gtatattggc
    44101 attaaaattt aaaagtataa aaatgatttt aataatatta tttaaaaatt tgattattat
    44161 tccatgtgca atcatattag cattaattag tttaagttat tttaaagaaa tggtttatga
    44221 atttaaaaag aaaaatagaa aaaatatgca atttttaatt aagaggtata tactaaatat
    44281 tataattata atagcactat cattggggtt gcaattaata ttaaatactg caagtattgg
    44341 tattattaag ttcctagcta aataaaggag tttataatgg atattataga gggatatata
    44401 gattacataa aagataaaaa aaaattatca gagaatacag tggcatcata ctttatggat
    44461 ataaaaaaat atatggaata tataaatcaa aaaagcatta aactagtaga tatagtagaa
    44521 aatgatatta taagttactt aataaagttg gaaaaagata atgtatcaat agctacaata
    44581 gcgaggatga tatcctctat aaaatctttt catgattatt tatttttaaa tcatatatgt
    44641 acaaataatc ctgcaaagga tataaaaaaa cctaaaataa aaaaagaaaa tataaatata
    44701 cttacagaag aagaaattga aagactatta aattttccaa agttaacaac acctaaattg
    44761 attagggaca aggctatttt tgaagtatta tatggtactg gtataaaagt atctgaatta
    44821 gtagagatga atatagagga tattgaccta gatattgatt atatatattg taattcatgt
    44881 tgtaaaaatc aaagagtgat accactttgt gatattacaa aactttactt agaaaagtat
    44941 ctaaaagaag caagacctaa aatggctgta gaaggtgaaa aatcattatt cgtaagttca
    45001 ttaggtcaaa ggtttacacg acaaggtctt tggaaagtca taaaaaaata ttctaatcta
    45061 gccaatatag ataaaaatat aaatcctaca atgcttagac attcatttgc tattcatttg
    45121 ttaaatgaag gtgctaacat tgctgttgta agtaaaattt taggaaatgt taatttatct
    45181 agtttgcaag tatatttaaa tcatatagat aaaaacgtga gaagagaaat aaaggagaaa
    45241 catcctagaa atgatgttga tgtagaatta caaaaagcag aagctaaata gactatatag
    45301 caaattttat aatttagaag gagcatattt atatgagcag agtaatttgg attgtaattg
    45361 atagtgttgg gataggagca ttgcctgatg ctgaaaaatt tggtgatagt aaggatgtaa
    45421 gtacccttgg aaatatattt aaggaatatc cagatattca gattcctaat atgagaaatt
    45481 taggtatagg aaacatagat ggtatagatt tttttgaaag tataaaagaa ccaataggtt
    45541 gttttggaaa gtgtaaggaa atgtctcagg gaaaagatac tactacaggt cattgggaaa
    45601 tgactggtat aatagttgac aaaccattta agacatttga acatggattc tctaaggaga
    45661 taatagaaga gtttgagaaa aaaactggaa gaaaagtagt aggaaataaa ccagcttcag
    45721 gaactgtaat aatagatgag tatggagaac atcaaataaa aactggagat gtaatagtat
    45781 atacatcagc tgatagtgta tttcagattg ctgctaatga agaagtaatt cccctagaag
    45841 aactctataa tatgtgcaaa atcgctaggg aaataatgat gggggataat gcagtagcta
    45901 gagtaattgc tagaccattc ataggtaaga aaaaaggtga gtttgtgagg acttcaaata
    45961 gaagagatta ttcactagac ccatttgaac caacagttct tgataatata aaagaatcag
    46021 gacttgatgt tttagcagtt ggaaaaatag aagatatttt taatggaaaa ggaattacag
    46081 atgctatcca cactaaaagc aatatggatg gagtggatga aactttaaat tatatgaaac
    46141 aagataataa aggtctaata tattcaaatc tcgttgattt tgattctaaa tatggtcata
    46201 ggagagaccc agaaggatat aagaaagctc ttgaagagtt tgatagtaga cttcctgaaa
    46261 taatggctaa tatgagagaa gatgatattt taataatcaa tgcagaccat ggaaatgacc
    46321 caacatataa aggtacagac catacaagag aatatatacc tgttatgatt tatggcaata
    46381 agattaaaaa aggttttaat ttaggagtaa aagatacttt tgctgatatt ggagcaactg
    46441 ttgcagatat actaaatgta aagttgccta aacatgggtc aagctttaaa gaagatttat
    46501 tttaaactat aaaatgataa aaacttagct taataggatg gagagattgg aatgtttgaa
    46561 aagatagcac aaagtagtaa atttataaat tctaaaagtg atataaaacc taagattggt
    46621 ttgatattag gttctggact aggtgattta gcaaatgata tagaagaccc tgtcgcaatt
    46681 aaatatagtg aaattccaaa cttccctgta tcaacagtag caggacatgc tggacaactt
    46741 gtaattggaa aacttgaagg aaaagaagtt attgctatgc aaggtagatt tcattactat
    46801 gaaggatatt ctcagaaaga agctactttt ccagtaaggg ttatgaaaga attaggagtc
    46861 gagattctta tagtaactaa cgctgctgga ggcgtaaata aagaatttaa agcaggagat
    46921 ttgatgctta taagagacca tataaacttt agtggaagta atccattagt aggaaaaaat
    46981 gatgacagat ttggtgctag atttccagat atgtcagatg catattcttc taaatatgta
    47041 gatgtagtta aaaactgcgc taaagaatgc aatatagatg tcaaagaagg cgtttatatg
    47101 ttttttagtg gtccaaacta tgaaacacca gcagaagtga gaatggcaca aattttggga
    47161 gctgatgctg taggtatgtc tactgttcca gaagtcatag tagcttctca ctctaatata
    47221 ggagttattg gtatatcttg tataacaaat atggctgctg gcatcttaaa tcaaccacta
    47281 agtcatgagg aagtaataga aactactcaa aaagttaaat cagaatttat gaatttagtt
    47341 aaaacaacgg ttaaaaattt ataagttaaa gcttattata gattttttga ggaagtttat
    47401 aataaaatag ttaatgttta atttgaaaag aattaataaa aagctgtctt gatatagaaa
    47461 gttatttcta ataaaggaca gtttttttat aatactacaa catttgaaag tgttttaaag
    47521 tttaatattt atttaaatta ttataggtta gaatggagat ttcaattatg agaatgtatg
    47581 atattataaa aaaaaagaga gataacctag agcttagtaa aaaagagata aactacttta
    47641 tagaaaacta ttcaaaggga gatatacctg actatcaagc ttctgcacta ttaatgtcga
    47701 tttatttaaa taagatgaat aaacaggaaa ctgtacatct tacagaagca atgatgaact
    47761 ctggagacat gataaaccta tctgagatag atggaataaa ggtagataag catagtactg
    47821 gtggtgttgg agataagact accatagctc ttataccttt ggttgcttca tgtggagcac
    47881 cagttgcaaa gatgtcaggt agaggtcttg gtcatactgg tggtactatt gataaattgg
    47941 agtctatacc aggtttttcg acagaaatgg agataagtaa atttattgat tctgtaaata
    48001 agtctaaaat agcagtttgt ggtcaaagtg caaaggtagc aattgcagat aagaaaatat
    48061 atgctcttag agatgttaca gcaactgttg ataatatatc attgatatca tcaagtgtaa
    48121 tgtctaagaa gttagcttca ggagctgatg caattgtgct agatgtaaaa actggtgatg
    48181 gagcatttat gaagacatta gaagagtctt ttgagttagc taaatctatg gttgatatag
    48241 gtactggtat gaatagagat acaataggga ttgtaacaga tatggatgaa cctttaggtt
    48301 ttgcagtggg aaactcttta gaagttatag aagcaattga gacattaaaa ggaaatggac
    48361 ctaaagacct tgttgagcta tgcgaagtat taggagcata tatgttggtt ttatcaaagg
    48421 tagcacatga ttttgaagat ggtgttgaaa aaataagaga atcaataaaa tctggtactg
    48481 ctatacaaaa actcaaagag tttatagaga atcaaggtgg taataaagat gtagtagatg
    48541 attattcttt attcaaaaaa tcaaagtata aatatccagt taaatcaact aaatcaggtt
    48601 atataagcaa aattaaagct gaagatgttg gtgtatcggc tatgattctt ggagcaggta
    48661 gagaaactaa agatgatatt ttagatttat cagcagggat aattttagaa aagaaagtag
    48721 gagattatgt aaatgaaggt gaagttttag cttacatgta ttataatgat gaacaaaagc
    48781 tttcattggc aaagggaaga tttattgatt cctactctat tgtagattca aaaatagaaa
    48841 aaaataaatt aatatatggt attgtaacta aagaagagat taaaaagttt tagaaaattt
    48901 tagaaaagtg attataaaag gcctaacatg tcaaaaataa tgttaggttt tttatttttt
    48961 gatagactat aaattatacc aaaaatatat attttaaaac attttttaca atataaataa
    49021 gtttattcta caagatgatt gaaaattaaa gtatctagtt ttataataga aaatggataa
    49081 atatacataa ggagtagatt atattatgaa ctttaaagaa aatagattga aaatagcagt
    49141 attaataatt gttattttga ttatcttagc aggtatattt gtgtttatac aaataggtcc
    49201 ttatgataaa aataacaaaa aagatgtaat tatcgacgtt ccaagtggag catctgttgg
    49261 aaaaatatct gacatattat atgaaaataa attaataaag aatgaactat tatttaaact
    49321 tttggtaaag gttagcaata aagctccgtc tataaaatca ggaacatact tacttaatca
    49381 atcgtattca aacaatgata taataagtct tttagtttca ggtaaaatat atcaggatgg
    49441 tataaaagtg actattccag agggagctac atctaaagaa attatagcaa tgttagtaag
    49501 taaaaattta ggagataaag ctacttttga aaatttaata aaaaaacctc aagaatttta
    49561 tgataaattt ccatatttga aggaagatgg aataacctct ttagaagggt tcttgtatcc
    49621 agaaacttat tattttaatt caaagaaaca atcagaagaa gatattttaa gcgaaatgtt
    49681 aaaagtattt gacagtaaat acacggacaa gtttaaaaag aaacaaaaag aattaaatat
    49741 gactcttcaa gaagtaatgg aaatggcatc aataattgag aaagaagctg ttcttgacaa
    49801 agacagacct ataatagcaa gtgtgtttta taatagactt aaggtaggta tgcctcttca
    49861 atcagatgct acaatacaat atatatttga agagagaaag aaaattgtaa catatgatga
    49921 tttaaaaatt gattcaccat ataatagtta taaaaataag ggattacctc ctacaccaat
    49981 atcaaatcct ggtataaaat ctattgaagc agcattatat ccagagaaaa cagactattt
    50041 atattttgta gctaagattg atggtggaaa taattatagt acaaactatc aagaccattt
    50101 aaaatacgtt aaagaatata aagaagcaag ggataaacaa tcaaaagata caaaagcaac
    50161 aaataaagaa aatacaaaaa aataaaccat gattataaaa agtctaacag ggtaagaata
    50221 atgttgggct tttttattga aaattgttat tcttagattt ataataaaga aagtgtaaat
    50281 atatataaca atatgaattt aaaaaataat aaattaatat aaaacttgaa tatttattat
    50341 tttagggagt gtttttatga gtaatatagt taatgatttg gttgaagatt atataagagt
    50401 gacattaaaa gaaaaagaag gatttttaaa agatttagaa atttatgcag aggaaaatag
    50461 tgttcctata atacataaag aagtttcaga tttattaaaa gtcttgttaa aggttcaaaa
    50521 accaaagaga attttagaag taggatgtgc aattggttat tcttctattt tttttgcaac
    50581 tattatagga aaagatgcag atataataac tgttgagaga aatgaaaaaa tgatagaaaa
    50641 agcaaaagaa aacataaaat tagctggatt tgacaataac ataactatac tagaaggaga
    50701 tgcagaagaa aaacttagtc aagtccaagg tgaatttgac cttatattta tagatgcagc
    50761 caaaggtcaa tataagctat tttttgattt agttatagat aaattaaaag atgggggact
    50821 tttagtatct gataatattt tgtataaagg tatggttgct catgatgatt ttgttgtaag
    50881 aagaaaaaag actatagtta aaagaatgag aaattattta gattatatat gtaattgtga
    50941 ctatttaagc acatcattgg taccaatagg tgatggtgta gcactaagtt ataaagaaag
    51001 taaaagaggt gatgtagatg gaattaaata aagtagaact tttagctcca gctggtgatt
    51061 tggagagatt gaaaatagct ataacatatg gagcagatgc cgtttatata ggtggagaaa
    51121 tttttggaat gaggtctgca gcgaagaatt ttagtaagga agatatggca gagggagtag
    51181 cttttgcaca tgaaagaggc aagaaagtat tcgtaacagt aaatataata cctcataatg
    51241 aagattttct acaattagaa gactatttgt tggaactaga agagatagga atagatgcag
    51301 ttataatagc tgacccagga gtgcttagtg tcattaaaaa agtaattccg aatatggaaa
    51361 tacatttaag tacacaagca aatacaacca attatctaag tgcaaacttc tggtacgagc
    51421 atggaataaa aagagttgta gtggcaagag aattatcttt tgatgaaata tctgagataa
    51481 gagcaaaaac acctttagat atggatatag aagcgtttat gcatggtgct atgtgtattt
    51541 cttattctgg cagatgttta ataagcaact atatgactgg aagagatgca aacaaaggtt
    51601 cttgtgctca atcttgtaga tggcaatatc atttggtgga agaaaaaaga cctggtgagt
    51661 attttccaat atacgaagat gaaaggggta cattcttctt taactcaaaa gatttatgta
    51721 tgatagagta tataccagag ttaatcaaat ctggtataac aagtttaaaa atagaaggta
    51781 gaatgaagac tgcatactat gtagctactg ttgtaagagc atacagaatg gcaatagatg
    51841 aattttacag agacccagaa aactggaagt tcaatccaat gtggatggaa gaactaaaaa
    51901 aaggtagtca tagacatttt acatcaggtt tttacttgaa taaaccaaca acagaagacc
    51961 aaaattatca atcagcatca tatgttagaa actatgattt tataggtata gttagagaaa
    52021 cagaagatga agatggtctt attgttgttg agcaaagaaa taaaatgtgt gttggtgatg
    52081 aaatagaagt tatgggacca tataaagaaa ctatgtttac taaaattgaa gaaatgtaca
    52141 atgaagaagg agaagctata gaatcagctc ctcatcctag acaaatagtg aagttaaagc
    52201 tatcagtaaa agttggtaaa gattatatgc ttagaaaagt tatagaagaa aaggttgaag
    52261 aataataaaa aattgataaa aatagtatta gccccttaga aattgtcaat aatgaaatta
    52321 tctaaggggt gatttcatgt caaaaaagaa gactccattt ttgaaaaaag tgggaaagag
    52381 aagctggtgt atatttacta taattttaat aatttatagt gttttaattt ataggctagt
    52441 tgatatacaa gtattaaaag gtgataaata caaacaaagt gttgaatcac aaagcgttga
    52501 gaaagtcgag ttaaatagtg gaagaggaat aatctatgat agaaacaaca agaagcttac
    52561 agatacaagt aaatctcagg tattaattgt tgaaaaagaa aaattaaata ataactataa
    52621 aattttggag cttattaaga aagctactaa gatgaatgat ttagatatat ataaagctgt
    52681 acaagagcaa ttgacacgcc ctataataca gattcagact aaaaatatcg ataagagtat
    52741 gaaaaaagaa cttgagaaaa atggaataat ggtagaagaa aaaactatga ggtacgcaaa
    52801 agatggttta ttatcacata caataggata tataaaagaa gatgataaat caggtcaatc
    52861 aggaattgaa aagagtatgg atagtgtact tagaaattca aatgaaaagt atataagtgc
    52921 ttttaaagct ggagatgcag gaaatgaaaa atctctaaac atactaaagg gaagtgtaaa
    52981 aactgttgat aataaggata aagatagaca tctaaaaact actattgatt ataacattca
    53041 aaaaaaatta gaacaaatac taaataaaga agaaaatcct acagcagcaa taatctcgga
    53101 agcatctaca ggtgaaattc ttgcaatgtg ctctagacct aattttgacc aaaatgacat
    53161 atcaaaaagt ttaaaaggaa aaaatggaga atttgaaaat agagttataa aagcgacata
    53221 tccaccaggg tctgtattta agatggtagt tttattttct gcacttgaaa atggtgttat
    53281 agatgagaac tatacttaca actgtacagg taagactaaa gttgggaata ctaatgaaat
    53341 actgcgatgt aataaaagag atggtcatgg tttccaaaac ttaagacaag ctttttctaa
    53401 ttcatgcaat cctgcatttt tagatatagc tatgaaactt ggaaaagaaa agatactcaa
    53461 atctgctgaa aaattacatt tatttgaaaa ggttgatatt ggtcttgatg aagaaaaaat
    53521 tagagaagct ccaaaaaaca tatcaataag aaatttagct ataggtcaag aaaatataga
    53581 atttacacca cttcaaataa atcaaatgac tcaaataata gctaataatg gaacattcaa
    53641 accactatac ttatataaaa gtcttgtgga caataatatg aatacaataa aaacttataa
    53701 gtcttcaaaa aaagaagaac ttatttctcc ttatgtgtgt acacaagtta aagaatatat
    53761 gaagtctgta tctaggattg gtacagctaa agacctaaaa gatattgaag gtggttgtgg
    53821 agttaaaact ggtacagctc aaagtagttt aaataaaaaa gctatagacc atggatggat
    53881 aacaggattt tatcctgaag aaagacctaa gtatgtaata actgtgttag tagaaggaac
    53941 tcaaaaagga aataaatctg caacacctat atttaaggaa atatgtgaaa gtataaaata
    54001 aattatgtac tataaaattt aaggatatat cgtaactttg attttagata gaaaattttg
    54061 tctaatgatg tacgatatat ccttttaaaa tatagtatta actttcttga acaagctctt
    54121 tttctagttt tttaagagct tttttttcga ttctagatac atatgacctt gatatatcga
    54181 gtttttgtgc aatttctctt tgtgtcttat agccataagg agttaaccca tatcttaact
    54241 ggacaatttc tctttctcta ggagtaagaa ttttgtttag ttgttcgtaa agttttccaa
    54301 cttgaacttt tagttcaact tcatcaagaa catagttagc ctctgtacca agtatatcta
    54361 aaagacttat ttcattacct tctttatctg ttccgatagg gtcttgtaga gatacttgag
    54421 ttttattttt tttgttagat ctaatattca ttaaaatctc attttcaata catctagaag
    54481 catatgttgc taatcgagtt cctttatcta tgttataagt ttctatagct ttaattaatc
    54541 ctattgtacc tatggatatt aaatcatcct gatcttccgt tgaattatta tatttctttg
    54601 ctatataagc tactaatctc atgtttcttt caattaatgt atcttttgca cttttatcgt
    54661 tttctatttt aaatttagtt aaatactcaa tctcttcttc aggggttaag ggtttttcaa
    54721 aagatttaag agctgccaat aggtcacccc cttttcaacg gtcactttaa attatatgaa
    54781 ggagacttat ccaagttgac tgttatctaa taaaataata tgcatatttt tagaatttaa
    54841 aacatatatt tgcaaacttt tgaatggaat atgacataaa gagtgggaat ttaaatttaa
    54901 gtttttgttg tatatatatg aaacaaggcg aagaaattat tgatttataa agtataaatt
    54961 ggaattgagg tgtcaataaa tataaaagga aatagtattt atatatgttt tggtgttgaa
    55021 gtaaaagatt aatgcaaagc attagagtct ataaaaatat gaatatagga ggtgtaattt
    55081 tacaatactt aaaaaagtaa atgtaattaa ttgtttgtat aaagttgatt acaagcaaaa
    55141 gtatcagtca tagttaatac tgttaaggat gaaggtggtg tgttaattta tatatgtatg
    55201 ggaagaaatt ttgattacaa tgaaaaaact tacaaaagat attta
//
LOCUS       DAEPHU010000018        55160 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 01A10CD0081
            SAMN05941466-rid12468953.denovo.018, whole genome shotgun sequence.
ACCESSION   DAEPHU010000018 DAEPHU010000000
VERSION     DAEPHU010000018.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941466
            Sequence Read Archive: SRR6291087
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 55160)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 55160)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068158.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 22:43:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,892
            CDSs (total)                      :: 3,805
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 87
            rRNAs                             :: 8, 1, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 55
            CDSs (without protein)            :: 55
            Pseudo Genes (ambiguous residues) :: 0 of 55
            Pseudo Genes (frameshifted)       :: 21 of 55
            Pseudo Genes (incomplete)         :: 28 of 55
            Pseudo Genes (internal stop)      :: 16 of 55
            Pseudo Genes (multiple problems)  :: 8 of 55
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..55160
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941466-rid12468953.denovo.018"
                     /strain="01A10CD0081"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            complement(<1..896)
                     /locus_tag="KR231_001179"
     CDS             complement(<1..896)
                     /locus_tag="KR231_001179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009243519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysozyme family protein"
                     /protein_id="HBH0003583.1"
                     /translation="MKLKHIALIGSLFPILFSLVLFFGVLISADSDDENSNFSSGITG
                     MNLSAEVLKHQPMVEKYARENGISEYVNVLLAIIQVESGGTAEDVMQSSESLGLPPNS
                     LDTESSIKQGCKYFASLLSSCKNQGIDDLNVAIQSYNYGGGYVGYVAGKEKKHTFNLA
                     ESFAREKSGGKKVTYTNPIAVAKNGGWRYGYGNMFYVELVNQYLTVAHFDNATAQAIM
                     NEALKYQGWKYVYGGSNPNTSFDCSGLVQWCYGKAGISLPRTAQAQYDATQHLPLSQA
                     KAGDLVFFHSTYNAGSYVTHVG"
     gene            complement(893..3055)
                     /locus_tag="KR231_001180"
     CDS             complement(893..3055)
                     /locus_tag="KR231_001180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBH0003584.1"
                     /translation="MKERIKGAFTKKKIFHFLKMALFVVALSLILLSLLGTVAHATGL
                     VDDTINVENLYSKYPLSNYQLDFYVDNSWSWLPWNWLDGIGKSVQYGLYCITNFVWTI
                     SLYLSNATGYVVQEAYKLDFINDMADSIGKSIQTLAGVTQNGFSSSGFYVGFLLLIIL
                     VVGLYVAYTGLIKRETSKALHAVINFVVVFVLSASFIAYAPDYIKKINEFSSDISTAS
                     LDLGTKIMLPNSDSEGKDSVDLIRDSLFSIQVEQPWLLLQFGNSNAEEIGTNRVEALV
                     SASPEVEDGKTREEVVKTEIEDNDNNNLTIPQVVNRLGMVFFLLFFNLGITIFVFLLT
                     GMMLFSQILFIIFAMFLPISFLLSMIPSYESMAKQAIVRVFNTIMTRAGITLIVTVAF
                     SISSMFYNISTDYPFFMVAFLQIVCFAGIYMKLGDLMSMFSLNANDSQSMGRRIFRRP
                     YLYLAHRARRMERRLAGAVTAGGVAGAVAGSTISNRKPTRNTATKDSRGNTSTSSMGQ
                     RAGSKVGAVLDTKNKVKDKANAVKENIKDMPTQTAYAVYSAKEKAKSSVSDFKRGMVQ
                     EQQSRQSGRLEKQEQHKKNIADKRMELQKAQEARQAQRKADGSATTGATRPHERPATA
                     SKPSAEKMQEVKRPAIAQTPKASEPVKTNVIKERPLSSGASDKKATQSAQITHRQNVE
                     KVVSQETRQNYTKDRRTKVQQTTEKTRNLVTKKGQKKK"
     gene            complement(3055..5505)
                     /locus_tag="KR231_001181"
     CDS             complement(3055..5505)
                     /locus_tag="KR231_001181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HBH0003585.1"
                     /translation="MFPIKYIDNNLVWNKDNEVFAYYELIPYNYSFLSAEQKFIVHDS
                     FRQLIAQSREGKIHALQIATESSIRSMQEQSKKLVTGKLKEVAYQKIDEQTEALVSMI
                     GDNQVDYRFFLGFKLMVTEEQLNLKNIKKSAWLTFTEFLHEVNHTLMNDFVSMPNDEI
                     NRYMKMEKLLENKISRRFKVRRLEINDFGYLMEHLYGRDGIAYEDYEYQLPKKKLNKE
                     TLIKYYDLIRPTRCVIEESQRYLRLEHEDKESYVSYFTVNAIVGELDFPSSEIFYFQQ
                     QQFTFPVDTSMNVEIVENRKALTTVRNKKKELKDLDNHAYQAGSETSSNVVDALDSVD
                     ELETDLDQSKESMYKLSYVIRVSAPDLDELKRRCDEVKDFYDDLNVKLVRPAGDMLGL
                     HSEFLPASKRYINDYVQYVKSDFLAGLGFGATQQLGETTGIYMGYSVDTGRNVYLQPS
                     LASQGVKGTVTNALASAFVGSLGGGKSFCNNLLVYYAVLFGGQAVILDPKSERGNWKE
                     TLPEIAREINIVNLTSDKDNAGLLDPFVIMKDKEDGATLAKEILTFLTGISTRDGDKF
                     PVLISAISKVSESEHRGLLNVITELRQENTPIANHIANHIASFTNYDFAHLLFSDGTV
                     ENTISLDNQLNIIQVADLVLPDKDTTFNEYTTIELLSVAMLIVISTFALDFIHSDRSI
                     FKIVDLDEAWAFLNVAQGETLSNKLVRAGRAMQAGVYFVTQSSGDVSKESLKNNIGLK
                     FAFRSTDINEIKQTLEFFGIDKDDENNQKRLRDLENGQCLLQDLYGRVGVVQIHPVFE
                     ELLHAFDTRPPVQRNEVE"
     gene            complement(5483..5881)
                     /locus_tag="KR231_001182"
     CDS             complement(5483..5881)
                     /locus_tag="KR231_001182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009274602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HBH0003586.1"
                     /translation="MKKIKSYTGIWNVEKVLYAINDFNLPFPVTFTQITWFVITEFII
                     ILFGDISPLSMIEGAFLKYFGIPVALTWFMSQKTFDGKKPYSFLKSQITYALRPKITY
                     AGKAVKLHKQTLNETITAVRSVNYVPDKIY"
     gene            complement(5998..6501)
                     /locus_tag="KR231_001183"
     CDS             complement(5998..6501)
                     /locus_tag="KR231_001183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004843360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antirestriction protein ArdA"
                     /protein_id="HBH0003587.1"
                     /translation="MIDDMAVYIANLGKYNEGYLVGAWFTFPIDEEDVKEKIGLNEQY
                     EEYAIHDTDNFPIAIGEYVSIEELNEMYEMIEELPDYIVECLDEFISHFGTLEEVVEH
                     KDDIYYYPDCETMTDVAYYYIDELQALGDIPPSLQNYIDYEAYGRDLDMGGCFIETSR
                     GMCEIPY"
     gene            complement(6519..7022)
                     /locus_tag="KR231_001184"
     CDS             complement(6519..7022)
                     /locus_tag="KR231_001184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004843359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antirestriction protein ArdA"
                     /protein_id="HBH0003588.1"
                     /translation="MQETRVLVETRGTTGEETISYWFELPIDVAEFEEKLGVGAESGD
                     YRIIEKVLPYADEVHEHTSVYQLNELDFMYRQLSSDMQEEYVSLLTVFENLEALYICR
                     NVITVYPDCKSMIDVARQKLMNDPTFKHLSEDCQEYYFDFEAYASHLQEHGKFLVTEH
                     GIFELPE"
     gene            complement(6941..7237)
                     /locus_tag="KR231_001185"
     CDS             complement(6941..7237)
                     /locus_tag="KR231_001185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005339688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HBH0003589.1"
                     /translation="MNDIFKDMQSKVGCDYISDLPSYKRKVWHEMKRLNLADYEERQL
                     EDFSKYVFGMSYQTLKDVMKQQKGREEQCRKQGCWWKREEQLAKKQYHTGLNCR"
     gene            complement(7326..7952)
                     /locus_tag="KR231_001186"
     CDS             complement(7326..7952)
                     /locus_tag="KR231_001186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009319953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HBH0003590.1"
                     /translation="MKYIMLHGLGQSSESWSDTVKVFNDDFEVLCPNLSDWLSGKTPC
                     YDTLYRTLETYCEQFEEPLNICGLSLGGILAMQYAIEHPEKVNSLVLIGTQYEMPKYL
                     LKMQNLIFRIMPCSAFEKMGFRKTDFINLCKSMMELNFKHELKKISCSVLVVCGDKDK
                     INKKASLELQQQIENAEIAIIENAGHEVNTDNPTLLGQKLNVFFKQYV"
     gene            complement(8023..8244)
                     /locus_tag="KR231_001187"
     CDS             complement(8023..8244)
                     /locus_tag="KR231_001187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002570387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0003591.1"
                     /translation="MNFGQNLYQWFLSNAQSLVLMAIVVIGIYLGFKREFSKLIGFLV
                     VALIAVGLVFNAGGVKDVLLELFNKIIGA"
     gene            complement(8245..8379)
                     /locus_tag="KR231_001188"
     CDS             complement(8245..8379)
                     /locus_tag="KR231_001188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017143882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3789 domain-containing protein"
                     /protein_id="HBH0003592.1"
                     /translation="MWVLLKDFLLVSMGMGIGVVLMCILNVGKEADYKMKQLEESEDN
                     "
     gene            complement(8392..9588)
                     /locus_tag="KR231_001189"
     CDS             complement(8392..9588)
                     /locus_tag="KR231_001189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003062030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
                     /protein_id="HBH0003593.1"
                     /translation="MVLNEEQWIKELREKRIAYGISQGRLALASGITREYLNKIESGK
                     MKPSKELLNILHEELARFNPEAPLTMLFDYVKIRFSTLDIQHIIKDILKLNINYMLHE
                     DYGHYSYTEHYSLGDIFIYTSSDEEKGVLLELKGRGCRQFESYLLAQQRSWYDFLMDA
                     LIDGGVMKRIDLAINDHTGILDIPELAEKCRKREYIGKSRSYKFYQSGELIKHREDDR
                     EYMGRTLYLGSLKSDVYFCIYEKDYEQYVKLGTPLEEADIINRFEIRLRNERAYYAVR
                     DLLTYYDAEQTAFSIINQYVRFVDEEPDKRKNDWKLNDRWAWFIGDNRQSLKLTTKPE
                     PYTLDRTLRWVQRQVAPTLKMLKKIDKGNGTDYMDTIEQQAKLTEKHEMIIKQQTTPA
                     KDLVES"
     gene            complement(9833..10249)
                     /locus_tag="KR231_001190"
     CDS             complement(9833..10249)
                     /locus_tag="KR231_001190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009290089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0003594.1"
                     /translation="MEIKEINKIIQSEDKDEKVKSVKCICINYGDFLADCEGFVQKRY
                     HDFKCNPKHQFEKKADTILENAIHEKNFMPDLFLIRLNRKQSACNSQIDFVFELLDKS
                     FLETDPIRKSEISEETLNLCLSADVSFIMVYIGMNR"
     gene            complement(10253..11635)
                     /locus_tag="KR231_001191"
     CDS             complement(10253..11635)
                     /locus_tag="KR231_001191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009290090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HBH0003595.1"
                     /translation="MRKIFNKGHRIRASDKHLVYHYCIGTLLFVFMAVLLLLNSKQLM
                     RTNWEHFSLLQNGLILSPYNFITILIATGVCVLVAFLYYRFCYDSFKKLLHRQKLARM
                     ILENKWYEADTVQDSGFFTDLQSRSREKIVWFPKIYYQMEKGLLHICCEITLGKYQDQ
                     LLRLEDKFESGLYCELTDKTLHDGYIEYTLLYDMIANRITIDEVRAENGCLRLMKNLV
                     WEYDALPHALIAGGTGGGKTYFLLTLIEALLHTNAVLYILDPKNSDLADLGTVMGNVY
                     HTKEEMIDCVNAFYEGMVQRSEEMKRHPNYKTGENYAYLGLPPCFLIFDEYVAFFEML
                     GTKESVGLLSQLKKIVMLGRQAGYFLIVACQRPDAKYFSDGIRDNFNFRVGLGRISEL
                     GYGMLFGSDVKKQFFQKRIKGRGYCDVGTSVISEFYTPLVPKGHDFLQTIGRLAQERQ
                     VMPEQQGKEN"
     gene            complement(11705..12496)
                     /locus_tag="KR231_001192"
     CDS             complement(11705..12496)
                     /locus_tag="KR231_001192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006573936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBH0003596.1"
                     /translation="MTLGEKIQKLRKQNGFSQEELAEKVTVTRQTISKWELNQSEPDL
                     DFIAQLSNIFNVSADYLIKEELTKPDELPFRKKRYQYYFSERSKRTMFVAISIVALIA
                     SIVCLICDYFTSDKLSWSFIAIEAIIAVWLVFLPCMLFKEKVIFKTLIICSIIPIPFL
                     AILALLLKVTTIFTLGSCISVLCIAIMWAIYGIFRKYHQRIFLSLGFSLLLLIFVPIV
                     IVRVTDYFLPQYEIVSKSDVFNGIITFAIALICFGIDYLTQHKNK"
     gene            complement(12640..13278)
                     /locus_tag="KR231_001193"
     CDS             complement(12640..13278)
                     /locus_tag="KR231_001193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016280180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HBH0003597.1"
                     /translation="MKYIFLHGLGQTSFSWNKTLEVMSDKWDILCPNLADWLYNERPC
                     YETLYKALERCCKQFNEPLTLCGLSLGGILAMQYSIEHSEKVHSLVLIGTQYAMPKKL
                     LKMQNIMFQFMPSSMFSKMGFQKADFISLCKSMIDLDFTHNLKDISCRVLVICGEKDK
                     PNKSASLQLGNLIPYAKITIISGAGHEVNIDAPIKLGNELNVFFNSSHNTER"
     gene            complement(13362..13745)
                     /locus_tag="KR231_001194"
     CDS             complement(13362..13745)
                     /locus_tag="KR231_001194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009588269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HBH0003598.1"
                     /translation="MRLSNGFVIDREKTFGELKFTAVRDVFLQNEDGTPSTQLKKRIY
                     DLKCSLHGGIIPVSVPPEVPLREFPYNAVVELVNPVADTVSRKTYTGADVDWYVKAED
                     IVLKNKGNQNAGSPQNNNSQGQQKK"
     gene            complement(13761..14087)
                     /locus_tag="KR231_001195"
     CDS             complement(13761..14087)
                     /locus_tag="KR231_001195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HBH0003599.1"
                     /translation="MEMKYVVPDMAQSFGTLEFAGESEPVFERDKNNRRVLARRSYNL
                     YSDVQKGENVVVEIPVQAGEKKFKYEQKVKLVNPKLYGRGYAIGDMGHTDYVLVADDI
                     VAVEEK"
     gene            complement(14322..17366)
                     /locus_tag="KR231_001196"
     CDS             complement(14322..17366)
                     /locus_tag="KR231_001196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SrtB-anchored collagen-binding adhesin"
                     /protein_id="HBH0003600.1"
                     /translation="MKKMLKRLCTGFLALATVVTALPTTPVHAESKQYWTESKERVGI
                     VEKVMNDGSIGSTFNEGHLTVEGEDAYCIDINTDFKNGYKIRTDASTRMSADQISDVA
                     LSIEYVKQYTDSHSGISNNHAYLLRQLVVWQRLSVHLGWQCDNVRASYDEIPKATQDE
                     VFAGARAFVKENKGRYECGGYIYSGEGQELGQFWAKLNVGNAKLQKTSNNTSITDGNG
                     NYSIAGATYGVFSDKDCTKQLATLTTDENGNTDVVEVKAGTVYIKELSAPAGYKVDKT
                     VYPLTIKAGETATLNVSDTPKVTDTLIELFKIDMETQKDNPQGNASLAGAEFTWKYYA
                     GFYNKDNLPAEATRTWVTKTVAETDSDGATHYITKLADAYKVSGDSFYMQGVKAVLPL
                     GTLTVEETKAPNGYLLDGAYMQAGDKSEQIKGLYVTQITEDGDLAVLSGSNQFSVSDK
                     VIRGGVKIQKRDLETGDTKPQGSATLKDTAFDIISLNDNAVLVEGKLYKKNEVVKTIR
                     TDIEGVASTSADLLPYGKFRIIESEAPDGYLTDGAKPIDFAITENGKIVDLTDEAHSI
                     YNQIKRGDIEGVKIGAGTHKRLADVPFRITSKTTGESHVVVTDDNGQFSTSADWASHK
                     HNTNAGKTSEDGVWFGTSEPDDSKGALPYDTYIIEELRSDSNKGFELIPPFEIVVSRN
                     NLVIDLGTLTDEYEKEISIHTTATSKDGEKTILAGKEVTIVDTVKLDGLEKGTKYQLK
                     GWQMLKEENAELIIDGKRVENDYTFVADEEEMKVEISYTFNASALGGKNLVTFEELYD
                     LSNPDEPVKVAEHKDIEDDGQTVLITERIIKIHTTATDKDGNKELEAGKDVTIIDTVT
                     LEGLEVGTQYKLVGWQMLKEENIELLINGKRVESDYTFTADSETMKVEVVFTFDATSL
                     DGKQLVTFEELYDLSNPDEPKKVTEHKDIEDKGQTITFKEKPEEPEKPETPPTPEKPS
                     RPSDSPKTGDSTNVMAFVVMLLASAGGLAGIFFYKRRKMKNS"
     gene            complement(17742..18950)
                     /locus_tag="KR231_001197"
     CDS             complement(17742..18950)
                     /locus_tag="KR231_001197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dicarboxylate/amino acid:cation symporter"
                     /protein_id="HBH0003601.1"
                     /translation="MKKKIGLVPKLIIGIIVGILIGSYAPEIIVQILVTVSTLFSAFL
                     KFVIPFIIIGFVTAGIADLATGAGKLLGITTGIAYGSTLIAGLLSFAVSTLIFPNFID
                     ASVASQIGDPEAGMLAPIFTIPLEPMVDVTAAIVFAFVMGLGISALRNHGKGETLFNF
                     FQEFQGIVTKTLSTVIIPLLPLYIAGTFANITIAGEVWTILGVFWKVYLVVIPLHFVY
                     MACQFTAAGVFSGKNPVRMLKNQVPGYLTAIGTQSSAATIPVNVGCAEKNGVSKQIRE
                     FVVPLCATIHLSGSMISITGFTTAVLMMNGMPHGIGVLFPYIAMLGIAMVAAPGAPGG
                     AIMSALPFLPMVGIPSDGGLASLMIALYLTQDSFGTACNVSGDNAIAVVVDKINDGMS
                     KKGNKEEQSA"
     gene            complement(19111..19500)
                     /locus_tag="KR231_001198"
     CDS             complement(19111..19500)
                     /locus_tag="KR231_001198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004455003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1232 domain-containing protein"
                     /protein_id="HBH0003602.1"
                     /translation="MEFLKIIINIVLDILKKILVRFKNAKFGLVFVFDLLKLPDFMTD
                     KRINIVDKIKVISVLIFTISYFVSGVDIIPEMIAGAFGFIDDAIVLIWSIGIVNEEIN
                     KYRVIAKKDKHSNIIENVEFSIKDEEE"
     gene            complement(19604..20605)
                     /locus_tag="KR231_001199"
     CDS             complement(19604..20605)
                     /locus_tag="KR231_001199"
                     /EC_number="6.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--ammonia ligase"
                     /protein_id="HBH0003603.1"
                     /translation="MSTIIPKDYKSSLNVIDTQIAIKKLKDFFEMRLSNELNLIRVSS
                     PLFVLPETGANDNLNGEKAVSFDIPFMNKNAEIVQSLAKWKRLALKKYGFEVGSGLYT
                     DMNAIRKNEELDNIHSLYVDQWDWELVIDKSSRNEKTLKDVVKRLYGVFKDTEIFVCS
                     MYEGIKEILPEEITFITSQELEDMYPELSPKEREDKIVKEKKAVFITQIGKTLISGEK
                     HDGRSPDYDDWELNGDILFYNPVLDSALELSSMGIRVDEESLDRQLKLAGCEERKEFD
                     YHKMLLNGELPYTIGGGIGQSRICMYFLQKAHIGEVQVGVWPQDMIQNCSSAGIELL"
     misc_binding    complement(20664..20919)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(21053..22243)
                     /locus_tag="KR231_001200"
     CDS             complement(21053..22243)
                     /locus_tag="KR231_001200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HBH0003604.1"
                     /translation="MSKYNFDRVIDRVGTDCVKWDFRTNCSTKAQKDGLPFWIADMDF
                     ECAEPIIEALRKKVEHKIFGYSSNDSDKYFNAVCDWYKRRFNWEINRKDIIFSPGVVP
                     AVAILVRILTNSNEGVIVQKPVYYPFEAKIKSNNRDVVNNPLIYENGTYRMDYDDLEE
                     KAKCSNNKVLILCSPHNPVGRVWREDELKKVVEICKKYDLWIIADEIHSDLIRKGFKH
                     TPLQSLCPEYKDKIVTCIAPSKTFNLAGMQLSNIIVNNDELKKKYQEEVTAVGVATSP
                     NPFAIVATIAAYNESEDWLNELNDYLDNNIQFIDEYLKENLPKVKLVYPEGTYLAWLD
                     FTAYGLNEVELEDLMFKKANVLFDEGYIFGKEGIGFERINVACPQSLLKECMDRLKTI
                     FENL"
     gene            complement(22524..23645)
                     /locus_tag="KR231_001201"
     CDS             complement(22524..23645)
                     /locus_tag="KR231_001201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 peptidase aminoacylase family protein"
                     /protein_id="HBH0003605.1"
                     /translation="METNKDYIEYVHKVYDYLHTIPEKGFEEYKTSEFVLKELEKMGF
                     ENINKGIAGTGIIVTIDSKKEGPVFAIRADMDALEFIIDGEKKMIHACGHDGHTSMLL
                     TAAKLIKERNLVKRGKLKILFQPGEEKLYGALRVIDSGLLDDVEEMVGMHLRPGQDCR
                     LGKAIPAMYHCASCIMEFTIKGITCHGSKPHLGVNAVDAVCLAVNAINAIRVNPAIPN
                     SIKVTNISVKGETYNNIPDEAFMALDIRAESNDIIEELKEKAIHAVKTAVSSINAEAV
                     LISKDGVPAAEFDEELVNLAEETIKDVLGADASIGIFKNSGGEDFHYYTQKLKCKTTY
                     IGLGADATPGFHNPNVTFDTKALEYGVDIWCRLVEKRLG"
     gene            complement(23706..24191)
                     /locus_tag="KR231_001202"
     CDS             complement(23706..24191)
                     /locus_tag="KR231_001202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004455006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjiG family protein"
                     /protein_id="HBH0003606.1"
                     /translation="MSEVAKKEVKVKKGNVIDAFIGGARNGFQISTNSMAPNVIFGFA
                     IISVFNLTGLLDVIGTIFTPVMSIFGLPGVAATAIMTIFISMGGASGVIAGLFTAGQI
                     SQAHVAILLPMLLLSGAQIQFMGRLLGTAELKTKYYPHMFVIATLNGCIAMLIMNYFV
                     V"
     gene            complement(24193..24861)
                     /locus_tag="KR231_001203"
     CDS             complement(24193..24861)
                     /locus_tag="KR231_001203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0003607.1"
                     /translation="MSKLESTTEKVEVKWYGYVALILGALFFSGIFKDAPGPLKVLDF
                     NNVLGSFGTLGTINDGVGTLAANFRGDGGTGPRDGWLYALTLIPSVMFALGVVRVIDH
                     LDGMKAAQKLLSPLLKPLLGLPGFAGLTLIASLQSTDAAASMTKELKDDGYIDEKQKA
                     VFCAFQFSGASAITNFFASGAALFPFIGDVPIFIPLALILIMKFVGANLLRLYLNKFD
                     KGEA"
     gene            25251..27275
                     /locus_tag="KR231_001204"
     CDS             25251..27275
                     /locus_tag="KR231_001204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009899983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HBH0003608.1"
                     /translation="MDKKKLILITHDKLNSDHYKEELTNFFGDEIIIETQNILDGIKE
                     NLEGDVVLSLSPLTSNFLIKHFKEDIEIIHGTKALSKLGYEKMMKLPPGTKSLLMTTN
                     KTSAFEMATYLYKIGINHIDFVPTYPDCDEIYDLDTAITPGQIRFIPKYIKNIVDLGW
                     RKISLDTYMSLLVVLKLKNEKFIEKLYKLSKETLSHDFLNTSLDNISKLKTILYMTID
                     EIGDGLIFFNTFNKVTFVNKSLLNMLGLDEKLIKSPSLMEYMPNSFLDKITKNLNIDN
                     MIIYIDEIDKKFILSKKPFYLYKNIEGCLITLKDVNNIEILEQKIRSDSVKRGYVAKY
                     KFNNIIGNSSIIKDCIKKAKKMALTDNPILITGETGTGKEAFTQSIHNHSNRKNKPFV
                     AINCASLPSELLESELFGYEDGSFTGAKKGGKKGLFELAHTGTIFLDEIGDMPHDLQV
                     KLLRVLQEKEIRKIGGTSIIPIDVRILAATNKDLEKLIIENKFRMDLFYRISMFTLDL
                     PPLRKRLEDIPLLLESFLKELPYKNIKLDKSLLEALNSYTWMGNIRELRNCIEYMAYM
                     GSNYLTINDLPQNISSKLNNNHMSSNMSIFNDLNQYDKNICISILKSLHMKPMGRTKL
                     MKFMEYNVTEYEVRNMLEYLTRNGYLISSKGRKGSSITEKGIKIIENNII"
     gene            complement(27505..28692)
                     /locus_tag="KR231_001205"
     CDS             complement(27505..28692)
                     /locus_tag="KR231_001205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3798 domain-containing protein"
                     /protein_id="HBH0003609.1"
                     /translation="MLRKITAFMLSICLIIGLTGCSLLVGKKDKEKIIDDFKVAVVTQ
                     PLSENKVQYNMVEEMAKEYEEENKIDKDKDGQTKVKQTIKHVVLPENFTSNIDSAINK
                     IVKLADDKEVQAIVVSTDQAGLLPALQKVKEKRPEIITISAPMGDDKNQLSQFVDVNL
                     GVSAEERGKVLAERSKEMGAKAFIHYASTDDLKDVNIAKRLEMIKETCKNIGLPFVQV
                     NTPNINTEEDKNKVKQFLNEDIEKQVKKYGKDINVFGVNEYMDEVILTKALELKYIVA
                     EQSNPSPIQTYPSVMGLKISEKDAQNYDKINDMISEKAKAFGMSNRLGGYPMPMDAFL
                     PSVAIYLATEMVKQDLTQEDVCDPDYLEAFTELRFGIGSEFTPLTEVLYNYQSVILSQ
                     LIY"
     gene            complement(28894..30165)
                     /gene="brnQ"
                     /locus_tag="KR231_001206"
     CDS             complement(28894..30165)
                     /gene="brnQ"
                     /locus_tag="KR231_001206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004455013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid transport system II
                     carrier protein"
                     /protein_id="HBH0003610.1"
                     /translation="MRDIFIVGFALFSMFFGAGNLMFPPFLGMESGKDWLIPLIGFVV
                     ADAGIAMLVIIATARCKGSMDDVLRRAGKGLARVMSVAALACLALLVIPRTCATTYEM
                     GIMPIFGDHGPVAKAVFSIIFFGLTLAFTIRSSKVIDIIGKYLTPALLLVLFVLIVKG
                     IISPAGPMSPEHMIDKNLFGEGISQGYQTMDALGAASMATIMLMSIIAKGYTSDKDQI
                     GMTIKAGFVACVFLAVVYGGLTYLGATVSTLYDTSIPQASLLVEITSILLYGQVGKVI
                     LGVIVALACLTTSTGLTASISTYFEGISKASYKQLVIGICVASMLISNLGVDSIIAIS
                     VPILQTIYPVLLAIVVMELAGKHIKNDNAFKGAAYVTLVISLLSAINGMTGAVPFIQS
                     LPLAGLGFNWVIPAILGGIVGNFIKSNKQVA"
     gene            complement(30306..30959)
                     /locus_tag="KR231_001207"
     CDS             complement(30306..30959)
                     /locus_tag="KR231_001207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pentapeptide repeat-containing protein"
                     /protein_id="HBH0003611.1"
                     /translation="MTKIIKVQKPKFTGELEIIENLEDILEDIFNDEKIFNKIIENEV
                     ISDLDSVRVSFESCIFRNVSFENCNLKKIDLLDVVFENCNLSNTFFDGGSIYRVEFKN
                     SKLIGVRFDDCILKNVLFKDVLGKYSNFSFSKFKIVSILDSNFENSVFQEVKGDNLVF
                     EYTNLKKANFNGTKLSGIDFTTNNIEGIEIGIDDIRGAIFDVSQAIDLTKLMGIIIK"
     regulatory      31288..31389
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00167"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="purine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="guanine and/or adenine"
                     /db_xref="RFAM:RF00167"
     gene            31462..32805
                     /locus_tag="KR231_001208"
     CDS             31462..32805
                     /locus_tag="KR231_001208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NCS2 family permease"
                     /protein_id="HBH0003612.1"
                     /translation="MVPNTNNVQPGGNNSSLSFLDKMFKFSERGSSLKTEVIGGVTTF
                     LTMAYIVFVNPAILSEAGMDKAALITVTILATAIGTLIFAILGNAPFALAPGMGLNAF
                     FTYSLVIGAGIPWQTGLGVVFLSGCVFFTLAVTGLRKTIADAIPRELAVASSAGIGLF
                     LAFVGLKNMGVIIANPDTIVSLADFTPTVLIALFALILMAILEYKKVKGGILISIVVA
                     TIISVIFGFVELPTAIISTPPSIAPVAFKLDIVGALKFSLIGPIFSFMFIDMFDSLAF
                     LITCCKQMGLEDENGEIKDLGRMLYADVSSTLIGSFLGTSTVTTFGESASGIAAGART
                     GLASIVTAALFLATLIFTPLLGIVPTYAAAPALVMVGVFMFESIKQIDFADSKIAVPA
                     FVTVLLMPLTYSISIGLCFGFISYIIMHVVAKETDKISITLWIIGLLAVVNLVLS"
     gene            32984..34348
                     /locus_tag="KR231_001209"
     CDS             32984..34348
                     /locus_tag="KR231_001209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HBH0003613.1"
                     /translation="MSQLLIKNAYLITMNADREVYENGSILIENNIIKEVGKFDINIV
                     DKDAEIYDAKGKILMPGLVNTHVHLSQQLGRGLADDVVLLTWLRERIWPYESSFNYED
                     SLISSTACCVELIKSGVTTFLESGGQYVDAMVEAVDKTGLRACLAKSVMDTGDGLPEA
                     WQKTTDEEINTQLDLFHKFNNTSNERIKIWFALRTIFNTTEELLVRTKELADKYNTGI
                     HMHIAEIADEISFVKQNNGVGTVEYLDKLGVLGPNLLAAHTVWLTHKEIDLFRLHDVK
                     VSHDPGSAMKVVLGFASIPEMLEKGIPVSIGTDGAPSNNRMDLMRDMYLTSLIHKGRT
                     LNPTVVPAEEVLEMATINGAKCALLEKEIGSLEVGKKADMIILNPDTIHCLPMHNPIG
                     NIVYSMTSENVDSTICDGKWLMKERKVLVVDESELLNKVKKQASKIKDKAEVKIPSKF
                     KIIK"
     gene            complement(34526..36391)
                     /locus_tag="KR231_001210"
     CDS             complement(34526..36391)
                     /locus_tag="KR231_001210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HIRAN domain-containing protein"
                     /protein_id="HBH0003614.1"
                     /translation="MENVFKRLQEFNGYDGYKESFEMNYLCIYESIPLREQVELANNL
                     VDEILNMYKSESNEIYLLEGSNSKSLICYFEIFMKKINTLVKEMIIDEKWLYKLTKEL
                     IYKSKKVEYVKLGLVLSEKYLNVENLREVVDTFSKSGEYVFYLSNTIKKLEFYNTYLF
                     NLSKKATGSIKVFAIVNMENLDSKINSYLIEDGYKDTKYERLLMNYIISIVDLNEYLE
                     KRDLDKEKINNLARLICNYLLSVEFKYIGNKLELVNRFLPTVVNYGTNFESLYSIFLI
                     AINVLKDENIECNKIEFEKEINGILLSEKWKNIYFEALRDASGKTEDIIKMSEIYDVN
                     LSFDDLLPYLNRDIRDFEVYWHISKKGTTSSRLKLLNFFEETFKIDDLIGKMKDIEKD
                     KLTQEYYDDMLFFIVLKGSKSLYPEGKNISLKGIFGNINEVRKESINILKRYREKLSL
                     EELKIVKEAYEKEKNVILKDELRRVLYESNNLKKEFVNIEKIKVDEHGKDIYLTSIAV
                     AGSRFRNREYLEKELEKSKIYYLTREKDNLYDEKAIKIVGETGYVIGYVPRKENYILS
                     NLLDGGKLLYCRVTEYNLYEDCIYANVYLSYKDVIETVENSLKMVLDKSRIKLIN"
     gene            complement(36627..37844)
                     /locus_tag="KR231_001211"
     CDS             complement(36627..37844)
                     /locus_tag="KR231_001211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004455016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBH0003615.1"
                     /translation="MNNKKYYPTAIALYFSYFLLGIGISILGQYKPEFSSMWGAKTLS
                     DGTLDVSIVLAVIAALGLGRLISYPFAGPISDKYGRKVSGLIGNFLHAIFFVGIVFSP
                     NFYIAYVFAIIGGAANSFLDTCVTPSCMEIFASLGTIANMFTKFTIALAQFLLPFIIG
                     FVAANSISFKVIFIVTAILIVVDAFLIAVLPFPPANNVIDNKGKTVKSEKMKFTPTSI
                     ALVCIGFTCTSTFVLWLNCNQELGKLYGMADPTKIQSFYSMGVICAVLITSLLIKKYI
                     KPIRILVIYPIIALLMLLVVYFVQTPTICMLGGFVIGYSAAGGVLQLTTSTANEMFPT
                     NKGKITSIVMIASSIANYVILNIAGIITKSGGVNGPKYVVLFNVAITFVGILLALFVN
                     MRYEKEKVYDYDV"
     gene            complement(38044..38907)
                     /gene="aroE"
                     /locus_tag="KR231_001212"
     CDS             complement(38044..38907)
                     /gene="aroE"
                     /locus_tag="KR231_001212"
                     /EC_number="1.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004455017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate dehydrogenase"
                     /protein_id="HBH0003616.1"
                     /translation="MEISGRTGLFALIGTPVGHSKSPVMYNYSFKKLDLDYRYLAFDI
                     TVDKVKEALLAIKTFNIKGANVTMPCKSAVTEYMDELSPAARIIGACNTIVNDNGKLV
                     GHITDGVGYVRNLKENGVEVKGKKITIMGAGGAATAIQVQCALDGAREISIFNPKDDF
                     YKRAEQTVENIKKDVPECVVNLYDLEDTNKLYEEIQSSDILTNATLIGMKPYDNETNI
                     KDTSVLRKDLVVTDVVYNPKKTKMIEDAEANGCKAIGGLGMLLYQGAEAFNLYTGLEM
                     PVEEVNELCFK"
     gene            complement(38989..40911)
                     /locus_tag="KR231_001213"
     CDS             complement(38989..40911)
                     /locus_tag="KR231_001213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890951.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HBH0003617.1"
                     /translation="MKISSMFTPIRIGSMTVPNRFVVPPMGNNFANTDGTLSETSKAY
                     YLERALGGFGLITIESSVVDKKAKGGPRKPCLYDDSTIDSFKNVIDACHDAGSKVSIQ
                     LQHAGSEGNEKVAGHPLKAASAIPASNGRNTPLAITTEEIYELIESYGDAALRAQKAG
                     ADAVEVHCAHGYLVSSFISQRTNKRVDEFGGCFENRMRLPRLIIENIRKKVGNSLAIL
                     CRINSTDDVPGGIDVHDSSVIAAYLEDCGIDGLHVSRSIHIHDEYMWAPTTLHAGFSA
                     ELVTEIKKAVSIPVITVGRYTEPQFAELMVRQGRCDLVAFGRQSLADPEMPNKAKNGK
                     LDEMIPCIACLQGCVPNMFQGKPIACLANPILGHEAELKPAEISKEVLVVGGGVGGML
                     AAWVCAKRGHNVTLVEKSEVLGGQMRLAAYPPGKGDITNLVRSYISKCNQYGVKICTN
                     TEATVELIKEKSPDVVIIATGATPLVLPIPGINDSGLIHAVDLLDGKKSCGKKVLVVG
                     GGMVGCEVAAFLGEQEHEVTVIELREEVGADVISEHRKFLMNDFENYNIHTITGAKVS
                     KFYDDGVDYLLTDGTEHDLKGFDSVVLAMGSRNYDPLSEVIKEVVKETYIVGDAVKAR
                     RALDATKEAFEVALNI"
     gene            complement(40975..41823)
                     /locus_tag="KR231_001214"
     CDS             complement(40975..41823)
                     /locus_tag="KR231_001214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar phosphate isomerase/epimerase"
                     /protein_id="HBH0003618.1"
                     /translation="MNNQKNLNIPITISSYTLGTEVSFRDRVRIAKEAGFDGIGLRAE
                     NYIDAKNAGVTDEEMIAILNEYDMKVTEVEYITQWGREEDRTEAQREKEQNVYHMAHL
                     FNVKHINCGLLEMIPEEQIITALGELCDRAGELIIGLEFMPYSGVPDLATAWRVVKGC
                     NRENAMLILDTWHWARAKQTAEDLAPVPADKIVSIQVCDVLETPYEKLRDESLHDRLA
                     PGEGYGNTEEFVKIIKEHNISPRVIGAEVISDSLISKGLSTAAETVFNATKKVLDKAW
                     SEVSPK"
     gene            42236..43117
                     /locus_tag="KR231_001215"
     CDS             42236..43117
                     /locus_tag="KR231_001215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HBH0003619.1"
                     /translation="MNLYHLRYFVTLAHLEHYTKAAENLSITQPSLSHAISLLENELG
                     VALFEKEGRNIVLTKYGKIFLKDVEKSLEILDSSVKSLKITGTGEGQIDLAFLRTLGT
                     DFIPDIVHKFLKSNPAKSIDFKFHTGVTTDIIQGLKERKYDIAFCSKLEKEKGIEFIP
                     VAKQDLVLIVPYSHPLAAKDTIDLKETIPYPQIVFNQRSGLRYIIDDMFKKINQQPNI
                     VYEVEEDQVIAGLVAKNFGIAVVPNMNMLSFTKVKVIQIIHPSWERNFYLAFIKDRYL
                     PPAIKNFKNFVIKNAQL"
     gene            complement(43325..44188)
                     /locus_tag="KR231_001216"
     CDS             complement(43325..44188)
                     /locus_tag="KR231_001216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004455022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3800 domain-containing protein"
                     /protein_id="HBH0003620.1"
                     /translation="MLSSYVKRVSKIIKKKYIMFIDESGRADINHEDPFTLTGVIFEY
                     KYAVSQGDYVCSLRKEMDAFKEYCFGTSNIGIHLTDISRKSRAFEKFDDSQIKLFYDE
                     LPLFLSRLECTIISVTVDKARLKKYYAPSKEPYVVAFIHVLQNFYSFVNNETVESARI
                     VIESRDDVSNLKVQKAFFDVFNNGTIYLDIDEELRDKVKGFIIAKKEDADYREGLEIA
                     DILCNPLSRARRGLIEANPKCMQYGEKNKIFKSVRNKIYTPTSVNDIRNWGFKEVPIV
                     EPVGPWLEKMR"
     gene            complement(44343..46277)
                     /locus_tag="KR231_001217"
     CDS             complement(44343..46277)
                     /locus_tag="KR231_001217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp22"
                     /protein_id="HBH0003621.1"
                     /translation="MKKSLKKYLVLALTLVLVFACGVPESSAASKHVIIVNSRKNTLG
                     YFVNNKLVKEFRVATGKKGSETPTGKTKVVNKIKNRPYYKGNIPGGSPRNPLGDRWMG
                     LALKGTYGDTYGIHGNNNESSIGKHISGGCIRMHNKDVRWLFDQVPVGSDVIIDYSND
                     SYVKIAAKYKINLNQTGWKTENGKKYYVKSDGTYQKNSWLKVNGKMYYFDASGVMQTG
                     WKTINNKKYYLGTDGARVSGWKVIDGKTYYFNSDGVMQTGWQEKNGKKYYLGSDGLAV
                     TGWQEIDGNKYYFDKTGIMQTGWQQIDGKSYYLDKDGKMLTGSQKIDGKDYTFNEDGT
                     INPTWDTIIGANRFDTAKKISSVGNWNADSSDTVILVNGNAIADGITATPLASSYDST
                     ILLTNTANLPTETVEEMKLLAPKTVILIGGENAISSKLEQEIKTTFNTETKRIAGQDR
                     YQTATRIAEELGNREEIKTAYMVSGNGEADALSVASKAGEEKQPIILVNKDGITEESY
                     KWLTERKLENAYFIGGPSAINDSVIAKMNDITTEDISGNRIYGDSRVDTNAKVIEKFY
                     GDTDLQAVLVSKSDALVDALSAGPLAVKLHSPIVLMDNSGLSSEQQRVFANKKVETPY
                     QIGGGVSYIVMDKLMDILAK"
     gene            complement(46389..47402)
                     /gene="galE"
                     /locus_tag="KR231_001218"
     CDS             complement(46389..47402)
                     /gene="galE"
                     /locus_tag="KR231_001218"
                     /EC_number="5.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="HBH0003622.1"
                     /translation="MAVLVAGGAGYIGSHTAIELLESGYEVVIVDNLSNSNSIVVDRI
                     KELSKKPVKFYNIDIRNKDEMHVVFKENNIESIIHFAALKAVGESVEKPIEYYSNNLI
                     STLNLFELMREYGVKKFVFSSSATVYGDPHTCPILEDFPLSVTNPYGRTKLMIEQMLV
                     DISKADKSLDIALLRYFNPVGAHKSGRIGEEPNGVPSNLMPYITKIAVGKLKELSVYG
                     NDYPTHDGTGVRDYIHVLDLAAGHVKALQKLEENPGLVVYNLGTGKGYSVLDLVKAFS
                     KASGKEIPYKIVGRRAGDVAMCYADSSKAEKELGWKAKYELEEMCEDSWRWQSMNPNG
                     YEE"
     gene            complement(47426..48295)
                     /gene="galU"
                     /locus_tag="KR231_001219"
     CDS             complement(47426..48295)
                     /gene="galU"
                     /locus_tag="KR231_001219"
                     /EC_number="2.7.7.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UTP--glucose-1-phosphate uridylyltransferase
                     GalU"
                     /protein_id="HBH0003623.1"
                     /translation="MTVKKAIIPAAGLGTRFLPATKSQPKEMLPIVDKPTLQYIIEEA
                     IESGIEEILIITGRNKKSIEDHFDKSVELELELEQKGKTEMLEMVRDISNMVNIHYIR
                     QKEPKGLGHAIYCAKSFIGDEPFAVLLGDDIVDSDVPCLKQLIDTYNEYKTTVLGVQK
                     IAKEDTNKYGILDVKHIEDRVYKVKDMVEKPAIEEAPSDIAILGRYIITPAIFSILEK
                     QTPGKGGEIQLTDALQTLGKQEAIYAYNFEGRRYDVGDKIGFLEATIDFALKRENLKD
                     DLMDYMRKKVSEK"
     gene            complement(48493..48813)
                     /locus_tag="KR231_001220"
     CDS             complement(48493..48813)
                     /locus_tag="KR231_001220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0003624.1"
                     /translation="MSSKYNVWTFNYEFLGLDSGDEKNNEVYYEIDLDEILNENYIDE
                     DIDSGLDSDGNSILGELISEMDIDEDVSVDMTYQELEVDLEDLDSYLDEDIDSDIKGI
                     LDEI"
     gene            complement(48803..50794)
                     /locus_tag="KR231_001221"
     CDS             complement(48803..50794)
                     /locus_tag="KR231_001221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0003625.1"
                     /translation="MLKLGEKIIYELSDGFELSGISRYSKEYKKLHITNLGNIIISKS
                     DEVNEDTGVKYIYSFSDNKEKLEAVLEDSQIIVYGNNLPFYIKSENSSKNVTANLTMK
                     ITLDEYDLICKSQREFIFYLKDNMTILSLDDNKFYMGGINKDNEKFIFISGKNRFEIN
                     FDDIERYILEDKRVSLKGYFHMEREGIIVRSVSIFNNNIDSVVPSDLNERVKDNQKIG
                     NLPKDCEIVFCKISGNIDGFDYKNTNMLLVKYQDQLIFINKKSKKTIVKSAKDNCSKL
                     NLGEDIILYDNKNVFNLHINDKNREIMQIDDLKDIENEIVGYTLKHAPFFIQEDFDSL
                     TILKSFQKEIISIKNSDIKDIVINKELENENSNFVETEIKFNNQKVLLNLSKSMVQKL
                     MQDVFIYAKQPLLKENSIEVIYKNWSKAMNDMIIFNFFGNIYYMKSEFDKILEKELND
                     EIRIEVINSLYKQIQEQRNNLDLLSAYMPRILENQEIDLFEKYNTKLDVQVFKQIKNL
                     LSDLSYNISSYLNEVEKSLDNIIFVISGEDKKKYNYRMLKESESASLDVFLKQAISRL
                     NHLVENMYPYYVDETSREMFKLFELLWKNYRNIDDDSIKEILFERITNTYVFKQLTLN
                     NSTKERRKDIIEKIYNSVDYGTNKLDENMFFTGGIKYVK"
     gene            complement(50917..53460)
                     /locus_tag="KR231_001222"
     CDS             complement(50917..53460)
                     /locus_tag="KR231_001222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPOR domain-containing protein"
                     /protein_id="HBH0003626.1"
                     /translation="MKVLSENNIIRNTVLNVTASFLKQESKINEKLDGVLEKKFEKVE
                     FNEAKYAELLKFNILFYKTLARNTEPLIGKWIVDKYIPEIDELEKDLELTTAKCRKYV
                     NKAMKEGLDSLKANDLNSFLAYDKMELSERRRRLEKDYKVLNLYKDLLNISLRKISLE
                     KKECGDLFLKNQADAKRELKREIIFCVNKILASNKDVVPNNVEENNEQNKVEIKATEI
                     EDLQLGKDNSENDMLLNEIKNSKVKHESKSNDIESKFIDKLNSLNNESISQTIHNEYK
                     KLCGLEELHSVEAYGFGKEIIKDFACATVVLEFLKRRNRDLIEGAMRLTIIGEFGPEN
                     FKEFVDYVIKNKTEISEDTWNKAQNLIKDNYSELENHEIASKRTRRNKDIDIEEYIYM
                     IKNADKDICFRSSISIEDDAEEGTKEEVDSNNQDIGDVVEDKDTTDKEYDSNKEDIIE
                     PENKKSKKKAKLFGFIKKDNEEAEQEEENLNDISPDIILDKPVENHQVKSEEIEQNEL
                     KEIKQEEPSQHIEEERSVKIEKPINNNLDEKVSSNNESKLEKESKNLEDKKAKEIKEE
                     KLENEKSVVIPIKKKENSNKKSKNSSKDKYRENKKEMKNYVSDKEDSLDDEEVVSKKS
                     RLKETIIAVVIVVIVGVGYFITVGNNKKNDKENIPKSSTQQQANNKLTEEEKKAQAEK
                     EKKEAEEKAKAEKEAQEKAQAEKKAKEMEAYKDGKGVYYTVYAGSLKVEKTAKETAKE
                     YEAKGISSTIIQENGYYKIKIGDYSQYGEAQEKCNELAKKSIDTYIAMYDKYYDYKLE
                     ELKESAPSLSAEELKQKYEDLRSELKNKSGYREYVKHLDKLYEEIVEGA"
     gene            complement(53738..54072)
                     /gene="rnpB"
                     /locus_tag="KR231_001223"
     ncRNA           complement(53738..54072)
                     /ncRNA_class="RNase_P_RNA"
                     /gene="rnpB"
                     /locus_tag="KR231_001223"
                     /product="RNase P RNA component class A"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00010"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00010"
     gene            54204..54881
                     /gene="srtB"
                     /locus_tag="KR231_001224"
     CDS             54204..54881
                     /gene="srtB"
                     /locus_tag="KR231_001224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sortase SrtB"
                     /protein_id="HBH0003627.1"
                     /translation="MKKLYRIVINIILVLVILYSGFNIYSKLTKYNHDTKISSELQKK
                     EYKKEDLSKINSDFKFWLSVENTNINYPVVQSKDNSYYLDKDFYKKDSISGTLFMDYR
                     NKSIDDKNIIIYGHNMKNKTMFNNLNKFKDADFFKKNNKIKITLNGKEFLYDVFSAYI
                     VESDYDYLKTNFNNESDYQNYINDITSKSLYKSPIKVNSNDKIVTLSTCTYEFDDARM
                     VIHGRLI"
     gene            complement(55041..55115)
                     /locus_tag="KR231_001225"
     tRNA            complement(55041..55115)
                     /locus_tag="KR231_001225"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(55081..55083),aa:Thr,seq:tgt)
BASE COUNT        17031 a        10558 c         7481 g        20090 t
ORIGIN      
        1 atgccgacgt gggttacata cgaaccagcg ttataggtag aatggaaaaa caccaagtcc
       61 ccagcctttg cctgcgaaag cggaagatgt tgggtagcgt catattgtgc ttgtgcggtt
      121 ctcggcaagg agataccagc ttttccatag caccattgca caagtccgct acaatcaaag
      181 gaagtgttgg ggttactgcc accatacaca tacttccagc cttgatattt caacgcttca
      241 ttcataatcg cttgtgccgt cgcattatca aagtgtgcca cggtcaaata ttgattgact
      301 aattccacat agaacatatt tccatagcca taccgccagc ccccgttctt cgcaacggct
      361 atcgggttgg tgtaggttac tttctttcca cccgattttt cacgggcgaa gctctctgca
      421 aggttaaagg tgtgtttttt ctcttttcct gccacatatc ccacatagcc accgccatag
      481 ttataagact gtatcgctac attcaaatcg tcgatacctt gatttttgca ggaagaaagc
      541 agggacgcaa aatatttaca cccctgctta attgaacttt ctgtatctaa ggaattaggc
      601 ggtaaaccaa gactttccga actctgcata acatcttctg ccgtaccgcc actttctact
      661 tgaatgatag caagcaatac attgacatac tcggagatac cgttttctct ggcgtatttt
      721 tctaccatag gctgatgttt caagacttct gcggataagt tcatacccgt aatgccagaa
      781 gaaaaattgc tgttctcgtc gtcgctgtcc gcactaatca acaccccaaa gaaaagcacc
      841 agagaaaaga ggataggaaa cagactgcca atgagagcga tatgtttcag tttcattttt
      901 tcttctgtcc tttcttcgtt acaaggttac gggttttctc tgtggtctgc tgaacctttg
      961 tcctacggtc tttggtgtaa ttctggcgtg tttcctgcga taccactttt tctacatttt
     1021 gcctatgtgt tatctgtgcc gactgggtcg ctttcttatc agaagcacca gaagataacg
     1081 gacgctcttt gataacattt gtcttgactg gctcacttgc tttcggagtt tgagctatgg
     1141 cagggcgttt gacttcctgc attttttccg cactcggctt tgaagctgtg gctggtcgct
     1201 catggggacg ggtagctccc gttgtcgctg atccgtcagc ctttcgctgt gcctgccttg
     1261 cttcttgtgc cttttgaagc tccatacgct tgtcagcgat atttttctta tgctgttcct
     1321 gcttttccaa acgccccgac tgtctggact gctgttcctg taccatgcca cgcttaaagt
     1381 cggacacgct ggactttgcc ttttcctttg cggaatacac cgcataagcg gtctgtgttg
     1441 gcatatcctt gatgttttct ttgacagcat ttgccttgtc tttcacttta tttttcgtat
     1501 ctaagacagc acccaccttt gagcctgcac gctgtcccat gctggaagta gaggtattgc
     1561 cccgactgtc ttttgtagct gtgttccttg tcggttttct gtttgaaatc gtgctacctg
     1621 ccaccgcacc agcaacaccg ccagcagtaa ccgcaccagc aagccgtctt tccatacgcc
     1681 tagccctatg tgccaagtat agatatggtc tgcggaaaat tcttcgtccc atgctttgac
     1741 tgtcgttagc gttcaaagag aacatactca ttaaatcgcc cagcttcatg tagatacctg
     1801 cgaaacacac tatctgtaag aacgctacca taaagaacgg atagtccgtg gatatattat
     1861 aaaacatact ggaaatgctg aacgccaccg ttacaatgag cgttattcct gcccgtgtca
     1921 ttatggtatt aaacaccctt acgattgcct gctttgccat gctttcatag ctcggtatca
     1981 tggaaagtaa aaagctgata ggcagaaaca tagcgaagat aataaaaagt atctggctga
     2041 acaacatcat gcccgtaagc aagaatacaa atatcgttat ccctaagttg aagaacagga
     2101 ggaagaacac catacccaag cggtttacca cctgcggtat cgtcagattg ttgttgtcgt
     2161 tgtcctcgat ttctgttttc acgacttcct ctctggtctt tccgtcctcg acctctggac
     2221 ttgccgatac aagagcttct acacggtttg tcccgatttc ctctgcgttg ctgttcccga
     2281 attgtaagag tagccacggc tgttccactt gaatagaaaa taagctgtcc cgtatcaagt
     2341 ccacgctgtc cttgccctcg ctgtcagagt ttgggagcat gatttttgtt cccaaatcaa
     2401 gtgaagcggt actaatatct gatgaaaatt catttatctt tttgatgtag tcgggagcgt
     2461 aggcaataaa cgaagcggac agcacgaaca ccaccacaaa gttgataact gcgtgaagtg
     2521 ccttgctggt ttctcttttt atcagtcccg tataggcaac ataaagtccc accaccaaga
     2581 taatgagaag caggaaacca acatagaagc cagagctgga aaaaccgttc tgtgttacgc
     2641 ctgcaagggt ctgtatgctc tttccgatac tgtctgccat atcgttaata aaatcaagtt
     2701 tataggcttc ctgcaccaca tagcccgtgg cattgctcaa ataaaggctt atcgtccaga
     2761 caaagttggt aatacagtaa agcccgtact gcaccgattt tccaatcccg tctagccagt
     2821 tccacggaag ccacgaccag ctattatcta cataaaaatc aagctggtag ttggaaaggg
     2881 ggtattttga gtaaagattt tctacgttta tggtatcgtc cacaagcccc gtcgcatgag
     2941 ctaccgtccc cagaagtgaa agcaggataa gggagagtgc cactacgaac agagccattt
     3001 tgagaaagtg gaaaatcttc ttttttgtga acgcaccttt tatcctttct ttcatcactc
     3061 cacctcattt ctctgtacgg gcggtcttgt atcaaaggcg tgtagcagtt cttcaaaaac
     3121 ggggtgtatc tgtaccacac cgacacgccc gtataagtcc tgcaataagc attgtccgtt
     3181 ctccaaatca cgcaagcgtt tctggttgtt ctcgtcgtcc ttgtcgatac cgaaaaactc
     3241 taaggtctgc tttatctcgt tgatgtcagt agaacggaaa gcgaatttta aaccgatatt
     3301 gtttttcaga ctttcctttg acacgtcgcc agaagattgt gtaacaaaat aaacgcctgc
     3361 ctgcatagct cgtccagcac gaaccagctt atttgataag gtttcgcctt gtgccacatt
     3421 taagaacgcc cacgcttcgt caaggtctac aatcttaaaa atacttctgt ctgaatggat
     3481 aaaatcaagg gcaaaggtac taatcacaat cagcattgcc accgataata attcaatggt
     3541 cgtgtattcg ttaaaagtgg tatctttatc tggcagtaca aggtcagcta cttgaatgat
     3601 attgagctgg ttatccagac tgattgtatt ttctactgtc ccgtccgaaa acagcagatg
     3661 tgcaaaatca taatttgtaa aactggcaat atgatttgcg atatggttcg caatcggtgt
     3721 attctcttgc cgtaattctg tgataacatt taacagtcct ctgtgttcgc tttcagatac
     3781 cttgctgatt gcactaataa gcacagggaa tttatctccg tcacgggtag agatacccgt
     3841 taaaaatgtt aagatttctt ttgccagcgt cgctccgtcc tctttatctt tcataatcac
     3901 aaatgggtca agaagtcctg cattgtcctt gtcgctggta aggtttacga tattgatttc
     3961 acgggctatc tctgggagcg tttctttcca gttgccacgc tctgatttag ggtctaagat
     4021 aaccgcttga ccgccaaaca gcacagcata atacaccaga agattgttgc agaacgactt
     4081 cccaccgcca agcgaaccga caaaagcaga agcaagggca tttgtaactg tgccttttac
     4141 gccctgcgaa gctaaagacg gttgcaggta cacatttctt cccgtatcaa cggaatagcc
     4201 catatagata cccgtagttt ctcctaactg ctgtgtagca ccaaaaccaa gccctgccaa
     4261 gaaatctgat tttacatact gcacatagtc attgatatat cgcttgctgg ctggaagaaa
     4321 ttcagaatga agccccagca tatccccagc aggacgcacc aactttacat tgaggtcgtc
     4381 gtaaaagtcc ttgacttcat cacaacggcg tttcagctcg tcaagatcgg gtgcagacac
     4441 ccgtatcacg tagcttaact tatacatact ttctttgctc tggtctaagt ctgtttccag
     4501 ctcgtccacg ctgtctaagg cgtccaccac atttgagctg gtttcacttc ctgcttgata
     4561 agcgtgattg tcaaggtctt tcaattcctt tttcttgttt cttactgtcg ttaatgcttt
     4621 tcggttctcc acgatttcta cattcataga agtatcaacg gggaatgtga attgctgttg
     4681 ctggaaatag aagatttcag acgacggaaa atcaagctcc ccgacaatcg cattgacagt
     4741 aaagtaggac acataacttt ccttgtcctc atgttccaat cgtaaatacc gctggctttc
     4801 ctcaatcaca caccttgtcg gacggataag gtcgtagtat tttatcagcg tttctttgtt
     4861 caattttttc tttggtagct ggtactcata atcttcatag gcgataccgt ccctgccgta
     4921 aagatgttcc atgagatacc caaaatcatt gatttccaag cgacgcacct taaaacgcct
     4981 tgatatttta ttttccagta acttttccat tttcatgtaa cggttgattt catcattcgg
     5041 catggaaaca aagtcattca tcagcgtgtg gttcacttca tggagaaatt ccgtaaacgt
     5101 cagccacgcc gattttttga tgttcttcag attgagctgt tcttccgtaa ccatgagctt
     5161 aaagccaaga aaaaaacggt agtccacttg attgtcccca atcatagata ctaacgcttc
     5221 ggtctgttcg tctatcttct gataggcaac ttcctttaat tttccagtta ccagtttctt
     5281 tgactgttcc tgcatacttc gtatggagct ttctgtggca atctgcaagg catgaatttt
     5341 accctcacgg gactgtgcga taagctggcg aaagctgtca tgcacgataa atttctgctc
     5401 tgcggatagg aaagaatagt tatacggtat caactcatag taagcgaaca cctcattgtc
     5461 cttgttccag acaaggttat tgtcaatata ttttatcggg aacatagttc acactcctta
     5521 ctgccgtgat tgtttcattc aaggtctgct tatgcagttt tacggctttt cctgcataag
     5581 tgattttagg tcgcaacgca taagttatct gtgatttcaa aaagctgtac ggcttctttc
     5641 cgtcaaaggt cttttgcgac ataaaccaag tgagagcaac gggaatacca aagtatttga
     5701 gaaatgctcc ctcaatcatg gaaagtggag aaatatcccc aaacagaatg atgataaatt
     5761 ccgtaatcac aaaccatgta atctgtgtaa aggtaacggg aaagggtaag ttaaagtcat
     5821 tgattgcata caagactttt tccacgttcc agatacccgt ataagattta atctttttca
     5881 agttctttca gctcctttcg taagtttcta aatggaaaag gacagccatt ttcagactgt
     5941 cccttaaaga gaaatacgct gtcagtagca acaatgcttg tcgctgatct tccagcgtta
     6001 gtatggtatc tcgcacatac ctcggcttgt ttcaatgaag caaccgccca tatccaaatc
     6061 tcgcccgtag gcttcatagt caatgtagtt ctgcaagctg ggtggaatat cccctagtgc
     6121 ctgcaattcg tctatgtagt agtaggcaac atctgtcatg gtttcacagt cgggataata
     6181 ataaatatcg tccttgtgtt ccacgacttc ttccagcgtc ccaaagtggc tgataaattc
     6241 gtccagacac tctacgatat agtcgggaag ttcctctatc atttcataca tctcgttgag
     6301 ttcttcaatg gaaacatact cgccaatcgc aatggggaag ttgtcggtat catggatagc
     6361 gtattcctca tactgttcat tcaagccgat tttttctttt acatcttcct cgtcaatggg
     6421 aaacgtgaac caagcaccga ctaaatagcc ctcattgtat ttgccaagat tagcaatata
     6481 aaccgccata tcatcaatca taagcaccac ctcatttcct actctggcag ttcaaagata
     6541 ccgtgttccg ttactaaaaa tttcccgtgt tcctgtaagt gagaagcgta ggcttcaaaa
     6601 tcgaaatagt attcttgaca gtcctcggac agatgtttaa atgtcgggtc gttcatcagc
     6661 ttttgccttg caacatctat catgcttttg cagtctggat aaacggtaat cacgttcctg
     6721 caaatataaa gtgcttctaa attttcaaac accgtaagta gtgatacata ttcttcctgc
     6781 atatcacttg aaagctggcg gtacataaaa tctaattcat tgagctgata cacgcttgta
     6841 tgttcgtgga cttcatcagc ataaggcaac accttttcaa taatacggta atccccactt
     6901 tctgcaccga cacctagctt ttcttcaaac tcggcaacat ctatcggcag ttcaaaccag
     6961 tatgatattg tttcttcgcc agttgttcct ctcgtttcca ccagcaccct tgtttcctgc
     7021 attgttcctc acgtcctttc tgttgtttca tcacatcttt taaggtctgg tacgacatac
     7081 caaacacata tttagaaaaa tcttctaact gtctttcttc atagtcagca aggttcagtc
     7141 gtttcatttc atgccatacc ttacgcttgt aagagggcag gtcagaaata taatcacagc
     7201 cgacttttga ctgcatatcc ttaaaaatat cgttcatgta atcactccaa tctgaaattt
     7261 aagtatgaaa aaagcagtca atcctaagac taactgcttt gtgtgtaggg atatgaaatt
     7321 gtttatcaga catattgttt gaaaaataca tttaactttt gccctaatag tgttggatta
     7381 tctgtattta cttcatgtcc tgcattttca ataatagcta tttctgcgtt ttctatctgt
     7441 tgttgcaatt ctaaagaagc ttttttattt atcttatcct tatcgccaca gacaacaagt
     7501 accgaacatg atattttttt cagttcatgt ttaaaattaa gttccatcat agatttgcat
     7561 agattgataa aatctgtttt ccgaaagccc attttttcaa acgctgaaca aggcataata
     7621 cgaaatatca gattttgcat ttttaacaga tactttggca tttcatattg tgttcctatt
     7681 aacactaatg agttcacttt ttctgggtgt tctatcgcat actgcatagc aagaatacca
     7741 cctaaagaaa gtccacaaat atttagcggt tcttcaaact gttcacagta tgtttccaat
     7801 gtccgataca atgtatcata acatggtgtt ttcccagaaa gccaatctga taaattaggg
     7861 cataaaactt caaaatcatc attgaatact tttacggtat cactccaact ttcagaagat
     7921 tgtcccaaac catgaagcat tatatatttc atttcatcac tcctagatac tgtgtttcat
     7981 atccacatta taccattcgc atatcagcac cacaataaaa ttttatgcac cgataatctt
     8041 attgaacagc tctaacagta catctttcac accgccagca ttgaatacca agccgacagc
     8101 aatcaaggca actaccaaga agccgataag tttggaaaac tcacgcttga aacctaagta
     8161 gataccgata accacaatcg ccataagcac taagctctgt gcgtttgata aaaaccattg
     8221 atataaattt tgtccgaaat tcatttaatt gtcctcgctt tcttctaatt gtttcatttt
     8281 atagtcagct tctttgccaa cattcaaaat acacatcaag actacgccaa tacccattcc
     8341 catagatacc agcaggaaat ctttcaataa tacccacatt tttcatcact cctaactttc
     8401 tactaaatct tttgcagggg tcgtctgctg tttgattatc atttcatgct tttctgtgag
     8461 ctttgcctgc tgttcgattg tatccatgta gtctgtaccg tttcctttat caatcttttt
     8521 cagcattttc aaggtcggtg ctacctgcct ttgtacccaa cgcaatgtgc ggtctaaggt
     8581 gtaaggctct ggctttgtcg tcagcttcaa actctgtctg ttatcgccga taaaccaagc
     8641 ccagcggtca ttgagtttcc agtcattttt tcgcttgtct ggttcttcat caacaaaccg
     8701 cacatactga ttgataatag aaaaggcggt ctgctctgcg tcataatagg tcagcaaatc
     8761 tcgtactgca taataggcac gttcattgcg aagccgtatc tcgaaacggt tgataatgtc
     8821 ggcttcttcc agaggtgtcc ccagcttgac gtactgctca taatcctttt catagataca
     8881 gaaatataca tcagatttca gcgaaccaag ataaagggta cgccccatat attctctgtc
     8941 gtcctctctg tgcttgataa gctcgcccga ctggtagaac ttataacttc tggacttccc
     9001 gatatattcc cgtttcctgc atttttccgc aagctctgga atatccaaaa tgcccgtatg
     9061 gtcgttgata gcaaggtcga tacgcttcat cacgccaccg tctatgagtg cgtccatgag
     9121 gaagtcatac cagcttcttt gctgtgccag caggtaactt tcaaactgtc ggcaaccccg
     9181 accctttaac tctaaaagga cacctttttc ttcgtcagac gacgtataga taaagatgtc
     9241 ccctaaagag taatgctccg tataactgta atgtccgtaa tcttcatgga gcatataatt
     9301 gatattcagt tttaatatat ctttgatgat gtgctgtata tccagcgtgg aaaaacgaat
     9361 tttcacataa tcaaacagca tggtaagcgg tgcttctgga ttgaaccttg ccagttcctc
     9421 atgcagaata ttaagaagtt cctttgacgg cttcattttt ccgctttcta tcttgttgag
     9481 gtattctctt gtaatgccag aagctaacgc caacctgcct tgtgagatac cgtaagcaat
     9541 ccgtttctcc cgtaattctt ttatccattg ttcttcattc agaaccatac ccccaatctg
     9601 taacgtgtga agttttttaa ggcgacttca cagccgattt ttgctaggaa accatgtcag
     9661 aagccttatg tttcctatgt tttttgtcta ttgtctattt gcaaacgtac ccctctgtta
     9721 gataccgagg ggttcatcag cagagcaggg acaagccctg ctctgcaaaa cggcttccac
     9781 ggtcgtattt gctccgccga ccgttcctgc cgttgtgcag gcagaaccta tcctacctgt
     9841 tcataccaat gtaaaccatg atgaatgaaa catcagcgga taaacataaa tttaatgttt
     9901 cttctgatat ttcactttta cggatagggt ctgtttccag aaaagactta tccagcaatt
     9961 caaaaacaaa atcaatctgg ctgttgcaag ccgactgttt tctatttaag cgtatcaaga
    10021 acaaatcggg catgaagttt ttttcgtgaa ttgcattttc aagaatagta tcagcttttt
    10081 tctcaaactg atgttttgga ttacatttaa aatcgtgata acgtttctgc acaaatccct
    10141 cgcaatcggc tagaaaatct ccataattga tacagataca ttttacgctc ttaactttct
    10201 cgtctttatc ttctgattgt attattttat tgatttcttt tatttccatg agttagttct
    10261 cctttccttg ttgttctggc ataacttgtc tttcttgtgc aagcctgccg attgtttgta
    10321 aaaaatcatg tccttttggg actaaaggcg tgtaaaattc gcttataacg cttgttccca
    10381 catcacaata gccacgcccc ttgatacgct tctggaaaaa ctgctttttc acatctgaac
    10441 caaacagcat accgtaacct aattcgctga tacgcccaag tcccacacgg aaattgaagt
    10501 tatctctgat accgtccgag aaatactttg cgtctggacg ctggcaggca acgataagga
    10561 aataacctgc ttgtcgccct aacataacga ttttctttaa ctggctaagt aaacccacgc
    10621 tttctttcgt cccaagcatt tcaaaaaacg ccacatattc atcaaagata agaaagcagg
    10681 ggggtagtcc cagataggcg tagttttcgc ccgtcttata gttcgggtgt cgcttcattt
    10741 cctcacttcg ctgtaccatg ccctcataaa aagcattaac gcaatcaatc atttcttctt
    10801 tggtatgata cacatttccc ataaccgttc ccaagtcggc aaggtcgcta ttcttcgggt
    10861 ctaagatata aaggacagcg tttgtgtgca gtaaggcttc aatgagcgtc agcagaaaat
    10921 aggttttacc gccaccagtc ccaccagcga taagggcgtg agggagtgcg tcatattccc
    10981 agacaagatt tttcattagt ctaagacagc cattctctgc ccgtacttca tcaatggtaa
    11041 tgcggttcgc tatcatatca taaagcaggg tatattcgat ataaccgtca tgcaaggtct
    11101 tgtcggtcaa ctcacaatac aagccacttt caaatttatc ctctaaccgt aaaagctggt
    11161 cttgatattt tcccagcgta atttcacagc agatatgaag cagtcccttt tccatttgat
    11221 aataaatctt tggaaaccag acgatttttt ctcttgatct gctttgcagg tcagtaaaaa
    11281 aaccgctgtc ttgtacggta tcggcttcat accacttatt ttccagtatc attcgtgcca
    11341 gcttttgacg gtgcaggagc ttcttgaaac tgtcgtaaca gaagcggtaa tacagaaaag
    11401 cgaccaatac acaaacacca gtcgctatca gtatcgttat gaaattgtaa ggggaaagta
    11461 tcaagccatt ttgtaacaag ctgaaatgct cccagttggt acgcatgagc tgtttgctat
    11521 tcaatagcag gagaaccgcc atgaatacaa acagaagcgt ccctatgcag tagtggtaga
    11581 caaggtgctt gtcgctggct ctgatacggt gtcctttgtt aaaaatctta cgcataaatc
    11641 aatcactcct ttctgggtac gaaaaaagca gtcaatccta agactaactg ctttgaaata
    11701 atatctactt atttttatgt tgtgttaagt aatctatacc aaaacatata agggcaatag
    11761 caaatgtgat tatgccatta aatacatcag attttgaaac aatttcatat tgcggtaaga
    11821 aatagtctgt aacacgaaca atgacaatcg gaacaaatat caaaagtaac agagaaaacc
    11881 ctaaactaag aaatatgcgt tgatgatact tgcgaaaaat tccataaata gcccacataa
    11941 tcgcaataca aaggactgaa atacaactgc caagtgtaaa aatggtcgtt acctttaata
    12001 acaaggcaag tattgctaaa aatgggatag gaataatact gcatattatc aatgtcttaa
    12061 aaattacttt ttccttgaaa agcatacaag gcaggaatac aagccaaact gcaataattg
    12121 cttcaatagc tataaaagac caagatagct tatcagaagt aaaataatca caaataagac
    12181 aaactatgct tgctattaaa gcaactattg atattgcaac aaacattgtg cgtttgcttc
    12241 tttcagagaa gtaatattga tacctctttt ttctgaatgg taattcatca ggcttcgtta
    12301 attcttcctt gataagataa tcggcagata cattgaaaat gttactaagt tgagctataa
    12361 agtctaaatc tggttctgat tgatttagct cccattttga aatagtttgt cgagtaaccg
    12421 ttactttctc tgcaagttct tcttgtgaaa acccattttg ttttcttaat ttttgtattt
    12481 tctctccaag tgtcatagac attctccttt tatcgttatt tgcataaaat cataaaaaat
    12541 aaaatgtcct atgtctacca acattagctg gaattaacgc aacgaaccat tgcaacagcg
    12601 tatttatagg catttacagc ttttagatta ctttgctttt tacctttcgg tattatgaga
    12661 actattgaaa aaaacattta attcatttcc caatttaata ggagcgtcta tatttacttc
    12721 atgtcctgca ccagatataa tcgtaatttt tgcgtatggt attaaatttc ctaattgtag
    12781 ggacgctgat ttattcggtt tatctttttc cccacatata accaatacac gacaagaaat
    12841 atctttcaaa ttatgggtaa aatctaaatc aatcatagac ttgcataagc tgataaaatc
    12901 tgctttttga aaccccattt ttgaaaacat tgagctaggc ataaattgaa acatgatatt
    12961 ttgcattttt agtaattttt ttggcattgc atactgtgtt cctatcagca ctaaagaatg
    13021 taccttttct gaatgttcaa tactgtattg catagcaaga ataccaccta gagataaccc
    13081 acacagcgtt agcggttcgt tgaactgttt acagcacctt tccaacgctt tatataaagt
    13141 ttcatagcag gggcgttcat tatatagcca gtctgcaaga ttaggacaca atatatccca
    13201 cttatcactc attacttcta atgttttatt ccaactgaaa gaagtctgcc ccagtccatg
    13261 tagaaaaata tatttcattt tgtttcactc ctacattttg atataccact tattatagca
    13321 ggtatcacat atccgctaca atgaaaatct attcagcaag cctatttttt ctgctgtccc
    13381 tgcgaattgt tgttctgtgg actgcctgcg ttctggttgc ctttattctt caatacaata
    13441 tcctctgcct ttacatacca gtccacatct gcacccgtat aggtttttcg tgataccgta
    13501 tcggctactg gattgacaag ctccacgact gcattgtacg gaaattccct taacggtact
    13561 tctggcggta cggacacggg gataattcca ccatgcagac tgcacttcaa atcatagata
    13621 cgctttttaa gctgggtact cggtgtcccg tcctcattct gcaagaacac atcacgcacc
    13681 gctgtaaatt ttaattctcc aaatgttttc tctctgtcaa taacaaaacc gtttgataat
    13741 ctcataaatt cttcactcct ttacttttct tcaactgcta caatatcatc agcaactaac
    13801 acataatcgg tatgtcccat atccccgatt gcgtaacctc tgccgtataa cttcggattg
    13861 acaagtttta ctttctgctc atacttgaac ttcttttcgc cagcctgcac gggaatttct
    13921 accacaacat tttcgccttt ctgtacgtca gaataaaggt tatagcttcg tctggctaag
    13981 accctgcggt tatttttatc tctttcaaag actggctcac tttcgcctgc aaattcaaga
    14041 gttccaaaag actgtgccat atctggcacg acatatttca tttccatatt gttttacctc
    14101 gtttctttct atttttgata aattgattgt gatttcttat tctggcggtt cgggaagtac
    14161 cagcaatccc ccagatagta aagggtaaaa tcaatgctta cgcacccttg actatccgtg
    14221 ttcttgcagg ttggtggcag acaagccaga ataagcggaa gtctgccgtt tgaccgcttc
    14281 ggcggagagc gtgatttttc tttcctcata ccgttaccgc cttatgagtt cttcatttta
    14341 cggcgtttgt agaagaagat acctgccagt ccaccagcag acgcaagcaa catcacaaca
    14401 aatgccatta catttgtact gtcgcccgtt ttgggactgt cgctcggtct gctaggcttt
    14461 tctggtgtcg gtggtgtttc gggtttttct ggttcttctg gcttttcctt aaaggtaatc
    14521 gtctgtccct tatcctcaat atccttatgc tcggtaactt tcttcggttc gtctggattg
    14581 cttaaatcgt acaattcctc aaaagttaca agctgtttgc cgtcaagaga agtagcgtca
    14641 aaggtaaaga caacttccac tttcatagtt tcgctatctg cggtaaaggt ataatcactt
    14701 tccacacgtt ttccattgat aagaagctct atattttctt ctttcaacat ctgccagccc
    14761 acaagtttgt actgtgtacc gacttctaat ccctctaagg ttacggtatc aatgattgta
    14821 acgtcttttc cagcttcaag ctctttgttg ccgtccttat cggtagcagt cgtatgaatt
    14881 ttgatgatac gctctgtgat aagtaccgtt tgcccgtcgt cctcaatgtc tttgtgttcc
    14941 gcaactttta cgggttcgtc tggattgctt aaatcataca attcttcaaa ggtaacaagg
    15001 ttcttgccac ctaaagcaga cgcattgaat gtataggaaa tttctacttt catttcttcc
    15061 tcatcagcga caaaggtata atcgttttct acacgtttcc cgtcaatgat aagttcagcg
    15121 ttttcttcct ttaacatctg ccagcctttg agctgatatt ttgtaccttt ttccaagccg
    15181 tccagcttca cagtatcaac aatcgtaacc tcttttcctg caaggatagt cttttcgccg
    15241 tctttgctgg ttgctgtggt atggatagag atttcttttt cgtattcatc agtcagcgtc
    15301 cctaaatcaa tcacaaggtt atttcttgat accacgattt caaaaggtgg gataagttca
    15361 aagcctttgt tgctgtcaga gcgtaattcc tcaatgatgt aagtatcata aggtaacgca
    15421 cccttgctgt cgtctggttc agaagttcca aaccacacac cgtcctcgct ggtttttcct
    15481 gcgttggtat tgtgcttatg agaagcccag tcagcagaag tggagaattg cccgttatca
    15541 tcagttacaa caacatgact ttcacctgtc gtcttgcttg tgatcctaaa gggaacatca
    15601 gcaagacgct tgtgtgtgcc tgcaccgatt ttcacaccct caatatctcc acgcttaatc
    15661 tgattgtaga tagagtgggc ttcgtcggtt aagtccacaa ttttaccatt ttctgtgatt
    15721 gcaaagtcaa tcggtttcgc accgtctgtc aaatatccgt ctggagcttc gctctcaatg
    15781 atacggaatt ttccataagg taagaggtcg gcagaagtag aagcgacacc ctcaatatct
    15841 gtacgaattg tctttaccac ttcgtttttc ttgtataact tgccctcaac caataccgca
    15901 ttatcattta aagaaatgat gtcaaatgca gtatctttca atgttgcact tccttgtggt
    15961 ttcgtatcgc ccgtttctaa atctcgtttc tgaattttca caccgccacg gataaccttg
    16021 tccgatacgg aaaactggtt acttccactc aatacggcaa ggtcgccgtc ctcggtaatc
    16081 tgtgttacat ataatccctt tatctgttcg gacttatccc cagcctgcat atatgcaccg
    16141 tccagcaagt agccgtttgg agctttcgtt tcctcaacag ttaatgtacc aagtggaaga
    16201 accgccttaa ctccctgcat atagaagctg tcgccagata ccttgtatgc gtccgctaat
    16261 tttgtgatgt agtgggttgc cccgtcgctg tctgtttcgg cgactgtctt tgtaacccat
    16321 gtacgagtag cttcggcagg gagattgtct ttattgtaga aacctgcata atacttccat
    16381 gtaaattccg cacctgctaa agaagcgttt ccctgcggat tgtctttctg tgtttccata
    16441 tcaattttga aaagttcaat caaagtgtcc gttacttttg gagtatcaga tacgttcaag
    16501 gtcgctgttt cgccagcttt gattgttaat ggatagactg ttttatccac tttatatcct
    16561 gctggtgcgg ataattcctt gatatagact gtgcctgctt ttacctctac aacatctgta
    16621 tttccgtttt catcagtcgt aagggtggca agttgtttcg tgcagtcctt atcagaaaag
    16681 acaccgtatg tcgcacctgc aatagagtaa ttcccgttac cgtctgtaat gctggtatta
    16741 ttggaagtct tttgaagttt agcatttccg acattcagtt tcgcccagaa ttgtcccaat
    16801 tcctgcccct cgccagagta gatataaccg ccacattcat agcgtccttt attttctttg
    16861 acaaaggctc ttgcaccagc gaaaacttcg tcctgcgttg cctttggaat ttcatcataa
    16921 gaagctctca cgttgtcgca ttgccagcca agatgtacgc tcaatctctg ccagactaca
    16981 agctgtctta aaaggtaggc gtgattgttg cttattccgc tgtggctgtc tgtgtactgt
    17041 ttcacatatt cgatagataa ggcaacgtcg cttatctggt cggcactcat acgggtgctt
    17101 gcgtcagttc tgattttgta accattctta aaatctgtgt taatgtcgat acagtaagcg
    17161 tcctcgccct caacggtcaa atgtccctca ttaaaggtag aaccaatcga accgtcattc
    17221 attacttttt caacgatacc gacacgctct tttgactccg tccaatattg cttactttct
    17281 gcatgaacgg gtgtagtcgg taaagcagta acgacagttg caagagctaa gaagcccgta
    17341 cacaatcgtt ttaacatctt tttcataaat ctaatgctcc tttcattttg ggtataaaat
    17401 agccgtccaa taagaacggc tgaaaataga aaaggaacgt catgttaggc gttccatagt
    17461 ctataagtta ttcaattttt tcttgtttca atactgatgt gctgtaccat atctttgcgt
    17521 atctaggaaa acttgcgtat caaggctcat tcgttagtag taaataagta gtaaattgat
    17581 gtgtttgttt ccttgaaaat gctgatagat actgtgtttt aggggataat cagattttta
    17641 ttgtgttttt aaataaaaaa atcactttat tttataattt tttataccat aaaaaatgag
    17701 ctatctctat ttgagataac tcatttttga ttattaaaaa actaagcact ttgctcttct
    17761 ttatttcctt ttttactcat tccatcattt attttatcta ctactactgc tattgcatta
    17821 tctcctgata cattacatgc tgtaccaaaa ctgtcttgag ttaagtataa agctatcatt
    17881 aaacttgcaa gcccaccatc tgatggtatt ccaaccattg gtaggaaagg aagtgcactc
    17941 attatagccc cacctggtgc tcctggtgct gcaaccattg ctatacctaa cattgcaata
    18001 taagggaata atacacctat tccatgtggc ataccattca tcattaaaac tgcagttgta
    18061 aatcctgtta ttgatatcat actacctgat aaatgtattg ttgcacaaag aggtacaaca
    18121 aattctctta tttgcttact tactccattt ttttctgcac aaccaacatt aactggtata
    18181 gttgctgctg aagattgagt tcctatagct gttaaatatc caggtacttg attttttaac
    18241 attcttactg gattttttcc tgaaaataca cctgctgctg tgaattgaca tgccatatat
    18301 acaaaatgta aaggtattac tactaagtat actttccaga atacccctaa tattgtccat
    18361 acttcccctg ctatagttat atttgcaaaa gttcctgcta tgtataaagg taataaaggt
    18421 ataatcactg ttgacaacgt tttcgttacg attccttgaa attcttggaa gaaattaaat
    18481 aaagtctctc cttttccatg atttcttaaa gctgatattc caagtcccat tacaaatgca
    18541 aatacgattg cagctgttac atctaccata ggctctaatg gaattgtgaa tattggagct
    18601 aacattcctg cctctgggtc tccaatttga cttgcaacac ttgcatcaat aaaatttggg
    18661 aagattaatg tagatactgc aaatgataat aatcctgcta ttaaggtaga accatatgct
    18721 attcccgtag ttatccccaa taactttcct gcacctgttg ctaaatcagc tatacctgct
    18781 gttacaaaac ctataattat aaatggtata acaaatttta ggaatgctga gaataaagta
    18841 ctaactgtta ctaatatttg tactattatt tctggtgcat aacttccgat taaaataccg
    18901 actatgatac cgatgattag tttgggcact aaacctattt ttttcttcat aatatttacc
    18961 ctccataact tttttaaatt aagcattctt gcacattgaa tacttagtta aatattggat
    19021 atccacttat tatgataata gagttttacc tctccgtcaa caatttaacc attttttgtt
    19081 aataaaaaaa agaataacat atataaattg ttattcttct tcatctttta tagaaaattc
    19141 tacattttca attatatttg aatgtttatc tttttttgcg ataactctat acttattaat
    19201 ttcttcattc actataccta tactccaaat taaaactata gcatcatcta taaaaccaaa
    19261 tgcccctgca atcatctctg gaattatatc aaccccagat acaaagtagg atatagtaaa
    19321 aattaataca gaaattacct ttattttatc aactatattg attcttttat ctgtcataaa
    19381 atcaggtagt ttaagtaaat caaatacaaa aaccaaacca aatttagcat ttttaaatct
    19441 gaccaaaatt ttttttaaaa tatctaaaac tatattaatg attattttta aaaactccat
    19501 atttatcacc tcttataatt ataggttatt ctacattata accgatataa ttaatttgat
    19561 gaacatatta gatataaatt ttatcaatta gtttatattt aaattataat aattcaattc
    19621 ctgcactact acaattttga atcatatcct gtggccatac tccaacttgt acttctccta
    19681 tatgagcttt ttgtaagaaa tacatacata ttcttgactg accaattcct ccaccaattg
    19741 tatacggaag ttcgccattt aaaagcatct tatgatagtc aaactctttt ctctcttcac
    19801 atccagcaag tttcaattgt ctatcaagag attcttcatc aactctaatt cccattgaag
    19861 ataattctaa tgctgaatct aaaacaggat tgtaaaataa tatatcccca ttcaattccc
    19921 aatcatcata atcagggctt cttccatcat gtttttctcc tgatattaat gtttttccta
    19981 tttgagttat aaatactgct ttcttctctt ttacaatttt atcttctctt tcctttggtg
    20041 ataattctgg atacatatct tctaactctt gtgatgttat aaaagttatt tcttctggta
    20101 atatttcttt tataccttca tacatactac atacaaaaat ttcagtatct ttaaatactc
    20161 catacaatct ttttacaaca tcttttagag tcttttcatt tctactactt ttatctataa
    20221 ccaattccca atcccattgg tctacataaa gagaatgtat attgtctaat tcttcatttt
    20281 ttcttattgc attcatatct gtatataaac cactaccaac ttcaaaccca tattttttaa
    20341 gggctaatct tttccatttt gcaagtgatt gaacaatttc tgcattttta ttcataaatg
    20401 gtatatcaaa gcttacagcc ttttctccat ttaaattatc atttgcacct gtttctggca
    20461 atacaaataa cggagaagaa actcttataa gatttaattc attacttagt ctcatttcaa
    20521 aaaaatcttt taattttttt atagctattt gtgtatcaat tacgttcaaa ctacttttat
    20581 aatcctttgg tattattgtg ctcatatcat tcactcccta tatttatata tttttccatt
    20641 aaaaaaaccc ttcatcccta tataaaaggg acgaaaggtt gcttttccgc ggtaccaccc
    20701 tgattagttt gaaataaatt caaacccagc tcacaatgta cagatattac tcgatacacc
    20761 ccaatatgat aacggtttgg ttccgactaa gcctactctt ttaaaatttc ggttagcaac
    20821 tccaggatgt tcttcattat agacttcata ttggtctcac accatcacca actcgcttta
    20881 attacattct ataactactc ttcctttcaa agtctttaag agtttaattc aataaaattt
    20941 agctctctta tgttttctat ttattcataa tagtatgata agtgattagt taaaatttgt
    21001 caagtttatt atttttttat ttttaaacac tttataaatt tttacctata ctttataaat
    21061 tttcaaatat agtctttaat ctgtccatac attcttttaa taaagactgt ggacaagcta
    21121 catttattct ttcaaatcct attccttctt ttccaaatat ataaccttca tcaaataata
    21181 cattagcttt tttaaacatt aaatcttcaa gttctacttc atttaatcca taagcagtaa
    21241 aatctaacca tgctagatat gttccttctg gataaacaag ttttactttt ggtaggtttt
    21301 cttttaagta ttcatcaata aattgtatat tattatctaa gtaatcattt aattcattaa
    21361 gccagtcttc actttcatta tatgctgcta ttgtagctac aatagcaaag ggatttggtg
    21421 aagttgcaac tccaacagct gtaacctctt cttgatattt cttttttagt tcatcattat
    21481 tcactattat attagacaac tgcattcctg ccagattaaa tgttttactt ggagctatac
    21541 atgtaactat tttatccttg tactctgggc ataatgactg taaaggagta tgtttaaatc
    21601 cttttctaat taaatcagaa tgtatctcat cagctattat ccataggtca tattttttac
    21661 atatttctac aacctttttt aattcatctt ctctccaaac tcttccaaca gggttgtgag
    21721 gactacaaag tatcagtact ttattgttgc tacacttagc tttttcttct aaatcatcat
    21781 aatccatcct ataagtacca ttctcatata tcagaggatt gtttacaaca tccctattat
    21841 tgctctttat cttagcttca aatgggtaat acactggttt ttggactatt acaccttcat
    21901 tagaattagt taatattctt actaaaatag caacagcagg tacaacacca ggactaaaaa
    21961 taatatcttt tctatttatt tcccagttaa atctcctttt ataccaatca caaactgcat
    22021 taaagtattt atcactatca tttgaactat atccaaatat tttatgttca acttttttac
    22081 gtaatgcttc tattattggt tctgcacatt caaaatccat atcagcaatc caaaaaggca
    22141 aaccatcttt ttgtgctttt gttgaacaat tagttctaaa atcccatttt acacaatctg
    22201 ttcctactct atctattact ctgtcaaaat tatacttact cattttttcc ctcctaagaa
    22261 taaaattttt ataattgtta agtctattac tagatgcact ttggtattat tttacaattc
    22321 ttaatattat aataatatca cttttttgtc caatagattt aaaatataat tacttttcca
    22381 tcatattttt tcaatattcc aaaatcagtt tcattatatc aaaataagat tgctcatatt
    22441 aattattttc taattaacat aagcaatctt tttctataac ttctataatt ataattttaa
    22501 atgtagaatt attagtttgg atgttatccc aatctctttt caaccaatct acaccatata
    22561 tctacaccat attctaaagc tttcgtatca aatgttacat ttggattatg aaatcctggt
    22621 gtagcatcag ctcctaatcc aatatatgta gttttacatt ttagtttttg tgtataataa
    22681 tggaaatctt ctccaccaga atttttaaat atacctatag atgcatcagc tcccaataca
    22741 tcttttatag tttcttcagc caagtttaca agttcttcat caaattctgc tgctggtact
    22801 ccatctttgg aaattagtac agcttctgca tttatagaac ttacagcagt ttttacagca
    22861 tgtattgctt tttcttttaa ttcttctatt atatcattac tttctgccct tatatctaaa
    22921 gccataaatg cttcatctgg tatattatta taagtttctc ccttaactga tatatttgtt
    22981 acttttatag aatttggtat agctggattt actcttattg catttattgc attcactgct
    23041 aaacagacag catctactgc atttactcct aaatgtggtt tagaaccatg acaagtgata
    23101 cctttaatcg taaattccat tatacagcta gcacaatggt acattgcagg tatcgccttt
    23161 cccaacctac aatcttgtcc aggtcttaaa tgcatcccta ccatttcttc tacatcatcc
    23221 aacaaaccag aatcaattac tcttaatgct ccatataatt tttcttcacc tggttgaaaa
    23281 agtattttta acttacctct ttttactaaa tttctctctt ttattaactt tgcagctgtt
    23341 aaaagcatag aagtatgacc atcatgacca caagcatgta tcattttctt ttctccatct
    23401 atgataaatt ccaatgcatc catatctgct cttatagcaa atactggtcc ttctttttta
    23461 gaatctatag ttactataat accagttcct gcaattcctt tattaatatt ttcaaacccc
    23521 attttttcaa gctcttttaa aacaaactct gatgtcttat attcttcaaa tcctttttct
    23581 ggtatagtgt gtagataatc atacacttta tgtacatact caatatagtc tttgttagtt
    23641 tccataatct agctcctcct taaaatttaa actttccatt tatattaaat ctttattata
    23701 attacctata ctacgaaata attcattata agcattgcaa tacaaccatt taaagttgct
    23761 ataacaaaca tatgtggata atatttagtt tttaactcag ctgttcctaa aagtctcccc
    23821 ataaattgta tctgcgctcc tgaaagcaat aacattggca atagaattgc aacatgtgct
    23881 tgacttattt gacctgctgt aaataaacct gcgattactc cagatgctcc tcccattgat
    23941 ataaatattg tcattatagc tgttgctgca acacctggaa gtccaaagat actcattaca
    24001 ggtgtaaata ttgtccctat tacatccaaa agacctgtta aattgaacac agaaattata
    24061 gcaaaaccga agatgacatt tggagccatt gaatttgtac ttatttggaa tccatttcta
    24121 gctcctccaa taaacgcatc tatcacattt ccttttttaa cttttacttc tttttttgct
    24181 acctcactca tgttaagctt cccccttgtc aaatttattt aaatataatc taagtaagtt
    24241 cgccccaaca aacttcataa ttaatattaa agcaagtggt ataaatattg gtacatctcc
    24301 tataaatgga aatagtgctg ctccagaagc aaagaaattc gtaattgcag acgcacctga
    24361 aaattgaaat gcacaaaata cagctttttg tttttcatct atatacccat catctttaag
    24421 ttctttagtc atagatgcag ctgcatctgt agactgtaaa ctagctatca aagttagtcc
    24481 tgcaaatcca ggtaacccta ataatggctt taatagtgga ctaagaagct tttgagctgc
    24541 cttcattcca tctaagtggt ctataactct aactactcca agtgcaaaca taactgatgg
    24601 tattaatgtc aatgcatata gccatccatc tcgagggcca gtacctccat cacctctaaa
    24661 gtttgcagct aatgtaccta caccatcatt aattgttccc aatgttccaa aagaacctaa
    24721 tacattgtta aaatccaata cttttaatgg tcctggtgca tctttaaata ttcctgaaaa
    24781 aaataatgct cccaatatta atgctacata cccataccat tttacctcaa ctttttctgt
    24841 tgttgattct aatttactca tataaattct ccctcctgtt taaatgaatt ttattagtat
    24901 acttgtttaa taagcaaaac ttatgccaat accttaatga taaagccttt gtatttattt
    24961 ttttattgta aatttattcc agtgattaaa tagcttataa ttacttactt ttcaagttta
    25021 aaaatataat atttttttat taattattta aaatatacat tacaatataa aaagctattt
    25081 tccttatctt gcaaaaataa ttttaaaata ggtttttata ggataaaatc ctaaaaaaac
    25141 ctattattta atcaaatata taaatttata ctactatttg ttgtataata taacttgcct
    25201 tatactttaa atactttaaa aataaatact attttgttag gagaaataaa atggataaaa
    25261 agaagttaat ccttataaca catgataaat tgaatagtga ccactacaaa gaagaattaa
    25321 caaacttttt tggagacgaa ataatcatag aaacacaaaa tatacttgat ggaataaaag
    25381 aaaatttaga gggagatgta gtgctttctc tatcaccttt aactagtaat tttttaataa
    25441 aacattttaa ggaagatatt gaaattattc atggaacgaa agcactttca aaacttggat
    25501 atgaaaaaat gatgaaacta cctccaggta caaaatcgtt acttatgaca accaataaaa
    25561 cttcagcatt tgagatggct acttatctat ataaaattgg tataaatcat atagattttg
    25621 taccgacata tccagattgt gatgaaatat atgatttaga tacagctata acaccaggtc
    25681 agattagatt tataccaaaa tacataaaaa atattgttga tttaggttgg agaaaaatct
    25741 cattagatac atatatgtca ttattagtag tattaaaact aaaaaatgag aaatttatag
    25801 aaaaactata caaattgtcc aaagagacac taagtcatga tttcttaaat acatcattag
    25861 ataatatatc taaattaaaa actatacttt acatgaccat tgatgaaata ggtgatggtc
    25921 taatattttt caacaccttt aacaaggtta cttttgtaaa taagtcttta cttaatatgt
    25981 tgggactaga tgaaaaactt ataaaatcac cttccttaat ggaatatatg ccaaatagtt
    26041 tcttagataa aattacaaag aacttaaata tcgataatat gattatatac atagacgaaa
    26101 tagataaaaa attcatactt tctaaaaaac cattttatct ttataaaaat atagagggtt
    26161 gcttaattac attgaaagat gtaaacaata tagaaatatt agaacaaaaa ataagaagtg
    26221 attctgtcaa aagaggttat gtagctaaat ataaatttaa taatattatt ggaaatagtt
    26281 ctattataaa agattgtatt aaaaaggcaa aaaaaatggc tcttacagat aatcctatat
    26341 taataacagg tgaaacagga acaggtaaag aagcctttac tcagtcaata cacaatcatt
    26401 caaatagaaa aaataaacct tttgtagcaa taaattgtgc ttcattacca agtgaattac
    26461 ttgaaagtga actatttgga tatgaagatg gttcttttac tggagcaaaa aaaggtggaa
    26521 aaaaaggatt attcgaatta gctcacactg gcactatatt tttagatgag ataggagata
    26581 tgccacatga tttacaggtt aaacttttaa gagtcttaca agaaaaagaa attagaaaaa
    26641 ttggtggtac aagtattatt ccaattgatg tgagaatatt agctgccaca aataaagatt
    26701 tagagaaatt aattatagaa aataaattta ggatggattt attttatagg ataagtatgt
    26761 tcactttaga tttacctcct cttagaaaga gattagaaga tatacctctt cttttagaat
    26821 catttttaaa agaacttccc tataaaaaca taaaactcga taagagtctt ttagaagctt
    26881 taaattcata cacttggatg gggaatatta gagaactgag aaattgtatt gaatatatgg
    26941 cttacatggg ttccaattat cttacaataa atgatttacc tcaaaacata tcttcaaaat
    27001 taaataataa tcatatgtca agtaatatgt ccatattcaa tgatttaaac caatatgaca
    27061 aaaacatatg catttctatc ctaaaatcat tgcacatgaa accaatgggg aggacaaagt
    27121 taatgaaatt tatggaatat aatgtcacag aatacgaagt aagaaatatg ctagaatatt
    27181 tgacacgcaa tggatactta atttctagta aaggaagaaa aggctcatca ataactgaga
    27241 aaggcataaa aataatagaa aataatataa tttaaaccta tagtaattca tctttacttt
    27301 atcaaaattt atatataatt ataatttttt atttttctat aaatttttta taaaataata
    27361 aaacttattt atattaaaaa cgaagctatc tcaatatagg gataagcttc tttttaattg
    27421 ttaaaaagat aaaaatatat ttgatttaat agaaaaagag tgcctcataa actaaaaagt
    27481 tcattttgag acacttcctt aatattaata aattaattgg cttaaaatta ctgattgata
    27541 attataaagt acctctgtta aaggagtaaa ttctgaaccg attccaaatc ttaattctgt
    27601 aaacgcctct aaataatctg ggtcacatac atcttcttgt gttaaatctt gtttcaccat
    27661 ttcagtagca agataaattg ctactgatgg tagaaaagca tccattggca taggatatcc
    27721 accaagtcta tttgacatgc caaaagcctt agccttttca cttatcatgt cgtttatttt
    27781 atcataattt tgagcatctt tttcagatat ttttagaccc ataacactag gatatgtttg
    27841 tattggtgat ggattgcttt gctctgcaac tatatacttt aattctaaag ccttagtcaa
    27901 tataacttca tccatatact catttacacc aaatacattt atatcttttc catatttttt
    27961 aacttgtttt tcaatatctt catttaaaaa ctgcttaact ttgtttttgt cttcttcagt
    28021 atttatattt ggagtattaa cttgtacaaa tggcaatcct atatttttgc aagtctcttt
    28081 aatcatttct aatcttttgg ctatattaac atctttcaaa tcatctgtag aggcataatg
    28141 aataaaagct tttgctccca tttcttttga acgttcagct aatacttttc ctctttcctc
    28201 tgcactaacc cctagattca catcaacaaa ttggcttaat tggtttttat catctcccat
    28261 aggggcagaa atagttatta tttctggacg cttttccttt accttttgta aagcaggtaa
    28321 aagccctgct tggtcagttg aaactacaat agcctgaact tctttatcgt cagccaactt
    28381 tactatctta ttaatagcac tgtctatatt agaagtaaaa ttctctggca atacaacatg
    28441 ctttatagtt tgtttaactt tagtttgacc atctttgtct ttatcaattt tattctcttc
    28501 ctcatattct tttgccatct cttccaccat attgtattgt actttatttt cagataatgg
    28561 ttgagttacc actgcaactt taaaatcatc tataattttc tctttatctt tcttgcctac
    28621 aagtaaacta caacctgtaa gtccaataat taaacatatg gatagcataa atgctgttat
    28681 ttttctaagc attaattaaa acctcctaaa tttgtacatt cttatcacta ttactaattt
    28741 tatcatactt caaagaaaaa ttatattata aaaaattata tacatgctat tataatccaa
    28801 tctaaaaagt actatgggta gattaggttt agattaaacc tacccatagt actaaaaatt
    28861 aatatattat aaaattaaat taattacaaa ttattatgct acttgtttgt tgctttttat
    28921 aaagttacca actattccac ccaatatagc tggtattacc cagttaaagc ccaaacctgc
    28981 aagtggcaag ctttgtataa atggaacagc tcctgtcatt ccatttatag ctgataataa
    29041 actaatcact aatgtaacat atgctgcacc tttaaaagca ttatcattct ttatatgttt
    29101 accagccaac tccataacaa ctattgctaa taaaacagga tatatagttt gtaggattgg
    29161 aactgatatg gctattatag aatcaacacc taaatttgat ataagcatac tagctacaca
    29221 tatacctata accagttgtt tataactcgc cttacttatt ccttcaaaat aagttgatat
    29281 tgatgctgtt aaacctgtag aagtagtcag acaggcaagt gccacaatta cacctaaaat
    29341 tacctttcct acttgaccat ataacaatat actagttatt tcaactaata aagatgcttg
    29401 aggtatacta gtatcatata aagttgaaac tgttgcacct aaataagtaa gaccaccata
    29461 tactactgct agaaatacac aggctacaaa accagcttta atagtcattc ctatttggtc
    29521 tttatctgat gtatatcctt tagctattat agacatcaac attatagttg ccatagatgc
    29581 tgcacctaga gcgtccattg tttgataacc ttgtgatata ccttcaccaa atagattttt
    29641 atctatcata tgctcaggac tcataggtcc tgctggagaa attataccct ttactattaa
    29701 aacaaataat actaataata acgctggagt taaatactta cctattatgt ctataacctt
    29761 agaagaccta atagtaaatg ctaaagttag cccaaagaag attattgaaa atacagcttt
    29821 agctactgga ccatggtctc caaatatagg cataataccc atttcatatg ttgttgcgca
    29881 agttcttggt attacaagaa gtgctaaaca tgctagagca gctacactca ttactcttgc
    29941 taacccttta ccagctctcc taagtacatc atccatgctt cccttacatc ttgctgttgc
    30001 tataataaca agcattgcta taccagcatc tgcaacaaca aatccaataa gaggaattaa
    30061 ccagtctttg ccggattcca tccctaaaaa tggaggaaac ataagatttc ctgcaccaaa
    30121 gaacatagaa aataaagcaa aaccaactat aaaaatatct ctcatctgct tactcacact
    30181 aaattacccc ctttgaaaat attttgaata ttaagataat cttactttat tttcagaaaa
    30241 atgtcaatct ggtaaaaatt cacacattgt taacgttttc ccaatttatt ttatgaatat
    30301 ttttttcatt ttatgataat tcccatcaat ttcgttaaat caattgcttg tgacacatca
    30361 aaaattgctc ctctaatatc atctatacca atctcaattc cctcaatatt attagtagta
    30421 aaatctatgc cagaaagttt agttccatta aagtttgctt tttttaaatt tgtatactca
    30481 aatactagat tgtcaccttt tacttcttga aatacagaat tttcaaaatt tgaatctaag
    30541 atagaaacta tcttaaattt agagaatgaa aagttagaat acttacctaa aacatccttg
    30601 aacaaaacgt ttttaagtat acaatcatca aatctaactc ctatcaattt actattttta
    30661 aattcaactc tgtatatact tcctccatca aaaaatgtat ttgataaatt gcagttttca
    30721 aataccacat caagtaaatc aatctttttt aaattacaat tttcaaaaga cacatttcta
    30781 aatatacaag attcaaagct aactcttaca gaatctaaat cacttataac ttcattttct
    30841 ataattttat taaatatttt ttcatcatta aatatatctt caagtatatc ttcaagattt
    30901 tcaataattt ctaattctcc tgtaaattta ggtttttgca ctttaataat tttagtcatt
    30961 ttcccctcca ctataaatta tattattttt gatattattt tttttaatat attaacttaa
    31021 tatacatatt tgatatatta aaaagttttt acgaaatatc catgtattca gtacttttat
    31081 aattatatca caaactcatt tataataaac ttccattaat agtataaaac aagttagaat
    31141 aattgacatt atattcatac atattcaatt attggaaaaa gtaatttttt tcaataaata
    31201 accttaattt tttataaaat cgacaaaaaa acgaataatt ttattatatt tattgtaaat
    31261 aatacaatat tacgatataa tacaacagaa aaacaaatag aaaatgttca tataatatta
    31321 gtaatacggt ctaatagttt ctacaaactc accttaaatg ggttttctat gaatagaatg
    31381 tcaactctga atatatgttc tattctatct atatgaatat atattttttt gtttatatct
    31441 taaagttttt tggaggtaaa aatggtacca aacactaaca atgtacaacc aggtggaaat
    31501 aattcatcat taagcttttt agacaaaatg tttaaattta gcgaacgtgg ctctagcctt
    31561 aaaacagagg taataggtgg agttactaca tttttaacaa tggcatacat agttttcgta
    31621 aatccagcaa tattatctga agctggaatg gataaagccg cccttataac agttaccata
    31681 ctagctacag ccattggtac acttatattt gcgattttag gaaatgcacc atttgctcta
    31741 gctcctggta tgggattaaa tgcattcttc acatactctt tggttatagg tgcaggaatc
    31801 ccatggcaaa caggtcttgg ggtagttttt ctatctggat gtgtcttctt tacactcgca
    31861 gtaacaggtc ttcgaaagac aattgcagac gcaattccta gagaattggc agtagcatct
    31921 tcagcaggta taggtctttt ccttgctttt gttggtttaa aaaatatggg tgttataata
    31981 gctaatccag atactatagt ttcacttgca gattttacac caacagtttt aatagctctt
    32041 tttgctctta tcttaatggc aatactagaa tataaaaaag ttaaaggtgg aatattgata
    32101 agtatagtag ttgcaacaat aatatctgtt atatttggat ttgtggagtt gccaacagca
    32161 ataatctcga cacctcctag tatagcacca gttgctttta aattagatat tgtaggtgca
    32221 ttgaaattct cattaattgg acctatattc tctttcatgt ttatagacat gtttgattca
    32281 ttagcatttc ttattacttg ttgtaaacaa atgggtcttg aagatgagaa tggtgaaata
    32341 aaagatttag gaagaatgtt atatgcagat gtttcttcta ctttaatagg ctcattctta
    32401 ggaactagta ctgttacaac atttggagaa tctgcttctg gtattgcagc aggtgcaaga
    32461 acaggacttg cttcaatagt aacagcagca ttattcttag ctacacttat atttacacca
    32521 ttacttggta tagttcctac ttacgctgca gctcctgcac ttgtaatggt tggtgtattc
    32581 atgtttgaaa gcataaaaca gattgatttt gctgatagca aaatagctgt acctgctttt
    32641 gttacagttt tattgatgcc tttaacttat agtataagta ttggtttatg ctttggattt
    32701 atttcatata taataatgca tgtagtagct aaagaaactg ataaaatcag tattacactt
    32761 tggattatag gtttacttgc agttgtaaac ttagttctaa gttaatattt ttaaatagtt
    32821 ctaggtcaat attttaaatt atatagaata aaatcttatt tattttaaat ttataaatag
    32881 caaaatcact ttatatgtaa attgattttg ctattaactt tgtatagaaa atttattatc
    32941 ataatatata gatataaaaa tatatagaaa aggagtggtg tttatgtcac aattacttat
    33001 aaaaaatgca tatctaatta ctatgaatgc agatagagag gtatatgaaa atggaagcat
    33061 acttattgaa aataatatta taaaagaggt tggtaagttt gatattaata ttgtagataa
    33121 agatgcagag atatatgatg ctaaaggaaa aatactaatg ccagggctag tcaatactca
    33181 tgttcactta tctcaacaat taggacgtgg tcttgcagat gatgttgtac ttttaacttg
    33241 gcttagagaa agaatttggc catacgaaag tagcttcaat tatgaagatt ccttgatttc
    33301 atctactgca tgttgtgttg aattgataaa atctggtgtc actacatttt tagaatctgg
    33361 tggtcaatat gtagatgcta tggttgaagc tgttgataaa actggactta gagcctgttt
    33421 agctaaatca gttatggata caggagatgg tcttcctgag gcatggcaaa aaactactga
    33481 tgaggaaatc aacactcaat tagacttatt ccataagttt aataatacat ctaatgagag
    33541 aattaaaata tggtttgcat taagaactat ttttaataca actgaagaat tacttgttag
    33601 aactaaagaa ctagctgata aatacaatac aggtatacat atgcatattg ctgaaatagc
    33661 tgatgaaatt tcatttgtaa agcaaaacaa tggagttgga acagttgaat accttgataa
    33721 actaggtgta ttaggaccaa atcttttagc tgctcataca gtttggctta ctcataagga
    33781 aattgattta tttagattac atgatgtaaa agtttctcat gacccaggtt cagctatgaa
    33841 agtggttcta gggtttgcat caattcctga aatgttagaa aaaggaatac ctgtttcaat
    33901 tggtactgat ggagctcctt caaataatag aatggacctt atgagggaca tgtatcttac
    33961 atcactaata cataaaggaa gaactttaaa cccaactgtc gtaccagctg aagaagtctt
    34021 agaaatggct actataaatg gagcaaaatg tgctttacta gaaaaagaaa ttggtagtct
    34081 tgaagtagga aaaaaagctg atatgattat tctaaatcca gatacaattc attgtttacc
    34141 aatgcataat ccaattggaa atatagttta ttctatgact agtgaaaatg tagactctac
    34201 tatttgtgat ggtaaatggt tgatgaagga aagaaaagta ttagttgtag atgaatctga
    34261 attattaaat aaagttaaaa aacaagcttc taaaataaaa gataaagcag aagttaaaat
    34321 tccatctaaa tttaaaatta taaaataaca taaatttcaa ttgttttgta aatatgaata
    34381 tataaatata tttatataca tcatatatac aaaacaattg tttttttatt ttatattcat
    34441 tagcattgct cataaaatac accataattc cagaaaaaat aaccaatcag ttaggattac
    34501 atcatctaag caatatataa acgtcttagt ttataagttt tattctactc ttatctaaaa
    34561 ccatctttaa agagttttca actgtttcaa ttacatcttt ataactcaag tacacatttg
    34621 cgtagataca atcttcatat aaattatatt cagttactct acaatacagc agttttcctc
    34681 catctaataa attgctcaaa atatagtttt cttttcttgg gacatagcct atcacatatc
    34741 cagtttcacc aactatttta atagcttttt catcatatag attatctttc tctctagtta
    34801 aatagtatat cttacttttc tccaattctt tttcaagata ttctctattt ctaaaccttg
    34861 aaccagcaac agctattgaa gtcaaataga tatccttacc atgttcatct acttttattt
    34921 tttcaatatt tacaaattct ttttttaaat tattactttc atataatact cttcttaatt
    34981 catccttcaa tataacattt ttttcttttt catacgcttc tttaacaatt tttaattctt
    35041 caagagatag tttctctctg tatcttttta agatatttat ggattctttt cttacttcat
    35101 ttatatttcc aaatattcct tttaaagata tattctttcc ttcaggatat agtgatttac
    35161 ttcctttaag cacaataaaa aataacatat catcataata ttcttgagtc aatttatctt
    35221 tttctatatc tttcattttt ccaattaaat catctatttt aaacgtctct tcaaaaaaat
    35281 ttaataattt taatctagaa cttgtcgttc cctttttaga tatatgccaa tatacctcaa
    35341 aatctctaat atctctattt agatatggca acaagtcatc aaaagataag tttacatcat
    35401 aaatttctga catttttata atatcttctg tttttccact agcatctctt aatgcttcaa
    35461 aatatatatt tttccatttt tcactgagca agataccatt tatttctttt tcaaattcaa
    35521 tcttattgca ctctatattt tcatctttta agacgtttat agctattagg aaaattgaat
    35581 ataaactttc aaagttagtc ccataattta ctacagtagg taaaaatcga ttcactaatt
    35641 ctaatttatt acctatatat ttaaattcta cacttagcaa gtaattgcat ataagacgtg
    35701 ctaaattatt tatcttttct ttatctaaat ctcgtttttc aagatattca ttcaaatcta
    35761 caattgaaat aatatagttc atcaataatc gttcgtactt tgtatcctta taaccatctt
    35821 caattagata ggaatttatt ttagaatcta aattttccat attaacaata gcaaatactt
    35881 ttattgaacc tgtagccttt ttagataaat taaataaata tgtattgtaa aattcaagtt
    35941 ttttaatagt attactcaga taaaatacgt attctccaga tttagaaaat gtatctacaa
    36001 cttctcttaa gttttctaca tttagatatt tctcacttaa aactaaccct agttttacat
    36061 actcaacttt tttactctta tatattaatt ctttagttaa tttatataac catttctcat
    36121 caataatcat ttcttttacc aaagtattta tctttttcat aaaaatttcg aaataacaaa
    36181 ttaaagactt agaattacta ccctccaata aataaatttc attagattca cttttataca
    36241 tatttaaaat ttcatctact agattatttg caagctctac ttgttctctt aacggtatac
    36301 tttcatatat acataggtaa ttcatttcaa atgattcttt gtatccatca taaccattaa
    36361 attcctgcaa tcgcttaaaa acattctcca ccaaattatc ctcctttaca tgatgtaatt
    36421 tatattgatt atactactta tttcatcaag tttacattta tacgcaaaaa aatattacta
    36481 gaaattgaaa ttctagtaat atccttatta ttaattatgt aaatacccta tcttataact
    36541 gtaaataata tccttattaa ttttaattac ttttaataaa aatctatcct agatttagac
    36601 ttctctatgc atatattata ctaatattag acatcataat catacacttt ttctttttca
    36661 tatctcatgt ttacaaacaa tgcaagtaaa attccaacaa atgttattgc cacattaaac
    36721 aatacaacat attttggtcc attaactccc cctgattttg taataatacc tgctatattt
    36781 aaaataacat agtttgctat actagatgca atcataacta tagatgttat ttttccttta
    36841 ttagttggaa acatttcatt tgcagttgac gttgttaact gaagaacacc tcctgctgct
    36901 gaataaccta ttacaaatcc ccctaacata caaatagttg gagtttgaac aaaatataca
    36961 actaatagca taagtaaagc tattatagga tatataacta atattcttat tggtttaata
    37021 tattttttaa taagtaaaga agttattaat actgcacata ttactcccat tgagtaaaag
    37081 gattgaattt ttgtagggtc agccatccca tacaatttac ccaattcctg attacaattt
    37141 aaccataata caaatgtaga tgtacatgta aatccaatac aaacaagagc tatacttgtt
    37201 ggtgtaaatt tcatcttctc tgatttaact gttttgcctt tgttatcaat aacattatta
    37261 gctggtggaa atggtaacac agctatcaaa aaggcatcta ctacaataag aatcgctgtt
    37321 actataaaaa taactttaaa tgatattgaa tttgctgcaa caaatccaat tataaaagga
    37381 agcaaaaatt gtgctaaagc tattgtaaat ttagtaaaca tatttgctat tgttcctaaa
    37441 ctagcaaata tctccataca agaaggagtt acacaggtat ctaagaatga atttgctgcc
    37501 cctccaatta ttgcaaatac atatgctata taaaaatttg gtgaaaatac aattccaaca
    37561 aagaaaattg catgtagaaa gtttcctata agaccactta cttttcttcc atacttatct
    37621 gaaataggtc ctgcaaatgg ataagatata agtctcccta atcctagtgc agcaataaca
    37681 gctaaaacaa tacttacatc caatgttcca tctgataatg ttttagcccc ccacattgat
    37741 gaaaattctg gtttgtattg tcctaaaatt gaaattccaa taccaagtaa aaaatatgaa
    37801 aaatacaacg ctatggcagt aggataatat tttttattgt tcataatttt tctcccattc
    37861 ttgttaattt attaacattt ttgtgtacaa taaactcatc cccataatgg atttaaagta
    37921 tagtcagtta aaacttcaaa tttaactgga ctatgaggca aaacccacta tgacaatttg
    37981 taatttatta ttaaaaatat tgaaatacgt atgttttttc attgtttaag atattactct
    38041 tatctattta aagcataatt cattaacttc ttctacaggc atttctaatc cagtatatag
    38101 attaaaagct tctgctcctt ggtataataa cattcctaat ccaccaatag ccttacatcc
    38161 attagcttca gcatcttcaa tcatttttgt tttcttagga ttataaacga catctgttac
    38221 tactaaatct tttcttaaaa cactagtatc ttttatattt gtttcattgt cataaggctt
    38281 cataccaata agagttgcat ttgtcaatat atcacttgat tgtatctcct cataaagttt
    38341 gtttgtatct tctaaatcat atagattaac aacacattct ggtacatctt tttttatatt
    38401 ctcaactgtt tgctctgctc ttttataaaa atcatcctta ggattaaaga tagatatttc
    38461 tcttgctcca tctaaagcac attgtacttg tatagcagtt gctgcaccac cagcacccat
    38521 aattgtaatc tttttacctt taacttctac cccattttct tttaaattac gaacatagcc
    38581 tactccatct gttatatgac caactaactt tccattgtca tttacaattg tattacatgc
    38641 tccaattata cgagctgctg gagaaagttc atccatatat tctgtaacag cagatttaca
    38701 tggcatagta acattggctc cttttatatt aaaagttttt attgctaaaa gtgcctcttt
    38761 taccttatct actgtgatat caaaggctaa atatctataa tctaaatcta atttcttaaa
    38821 actataatta tacatcactg gtgatttaga gtgaccaacc ggtgtaccta ttaatgcaaa
    38881 taatcctgtt ctacctgaaa tttccataac tataatctcc tctcaatatt atcattttct
    38941 ttgcaaataa cctattcagt tatttacaaa gaaaaattta tttattattt atatatttaa
    39001 tgctacttca aaagcttctt ttgttgcatc taatgcccta cgagctttta ctgcatcacc
    39061 aacaatataa gtttctttta caacttcttt tataacttca cttaatgggt cgtaattacg
    39121 agaacccata gcaagtacta ctgaatcaaa accttttaaa tcatgctctg tgccatctgt
    39181 aagtaaatag tcgacaccat catcataaaa tttagaaact tttgcaccag taatggtatg
    39241 tatattataa ttttcaaaat cattcataag gaatttacgg tgttctgaaa ttacatctgc
    39301 accaacttct tctctaagct caataacagt aacctcatgt tcttgttctc caaggaaggc
    39361 tgccacttca catccaacca ttccacctcc aacaacaagt acttttttcc cacaagattt
    39421 tttaccatca agaaggtcta cagcatgaat taatcctgaa tcattgattc ctggtatagg
    39481 aagtacaagt ggagttgctc cagtagctat aataactaca tcaggtgatt tctcctttat
    39541 aagttctact gtagcttctg tattagtaca tatttttaca ccatattgat tacattttga
    39601 aatataactt ctaactaagt tagtaatatc tcctttccct ggaggatatg cagctaaacg
    39661 catttgccca ccaagaactt cagatttttc aactaaagtt acattatgtc ctcttttagc
    39721 acatacccat gctgcaagca tacctccaac acctccacca acaacaagaa cttctttgct
    39781 aatttcagct ggcttaagct ctgcttcatg tcctaatata ggatttgcaa gacaggctat
    39841 aggtttgcct tggaacatat ttggtacaca tccttgtaag catgcaatac atggtatcat
    39901 ttcgtctagt tttccatttt tagctttatt aggcatttct gggtcagcca agctttgtct
    39961 accgaatgct actaaatcac atcttccttg tctgaccatt aactcagcaa actgtggctc
    40021 tgtataacgt ccaactgtta ttactggtat actaacagct ttttttattt cagtaactaa
    40081 ttctgcactg aatccagcat gtaaagtcgt aggagcccac atatattcat catgtatatg
    40141 tatactacgt gaaacatgaa gtccatctat tccacaatct tctagatatg ctgctattac
    40201 tgaactatcg tgtacatcaa ttcctcctgg aacatcatca gtgctgttta tacgacataa
    40261 tattgctaga gaatttccta cttttttacg tatattttca atgataagac gaggtaatct
    40321 cattctattt tcaaaacatc caccaaactc atctacacgc ttatttgttc tttgtgatat
    40381 aaaactacta accagatatc catgagcgca gtgaacttca acagcatctg caccagcttt
    40441 ttgtgcacgt aatgcagcat ctccataaga ttctataagt tcatatattt cttctgttgt
    40501 tattgctagt ggtgtattac gaccatttga tgcaggtatt gcagaagcag cttttaatgg
    40561 atgtcctgct actttttcat ttccttcaga accagcatgt tgtaattgta tagatacctt
    40621 cgaacctgca tcatgacaag catctattac atttttaaaa ctatctattg tgctatcatc
    40681 atataaacaa ggcttacgag gacctccttt tgcttttttg tctacaacac tagattctat
    40741 agttattaat ccaaaaccac ctaaagcacg ctcaagataa taagccttag aagtttcact
    40801 taaagtacca tctgtgtttg caaaattgtt tcccataggg ggaactacaa aacgatttgg
    40861 aactgtcatt gaaccaattc ttataggtgt aaacatagaa ctaatcttca taaggttttc
    40921 cttcctttca agttttatat tataatactc tgtatatttt tatattatat aagtttattt
    40981 tggagatact tcagaccatg ctttatccaa aactttttta gttgcattaa atacagtttc
    41041 agcagcagtg gataaccctt tagatattag agaatcagat attacttctg cccctatgac
    41101 tcttggtgat atattgtgtt cttttattat tttcacaaat tcctctgtgt ttccatatcc
    41161 ttcacctgga gccaaacggt catgtagtga ttcatcccta agtttttcat aaggagtttc
    41221 taaaacatca cacacttgaa ttgatactat cttatctgct ggaacaggtg caaggtcctc
    41281 tgctgtctgc tttgctctag cccagtgcca agtatctaat ataagcattg cattttcacg
    41341 attacatcct ttcacaacac gccatgcagt agccaaatct ggtacaccac tatatggcat
    41401 aaactcaaga cctataataa gttcacctgc tctgtcacat aattctccca atgcagttat
    41461 aatttgttct tctggtatca tctctaataa tccacaattt atatgtttaa cattaaataa
    41521 gtgagccata tgataaacat tttgctcttt ttctctttga gcttccgttc tatcttcttc
    41581 tcttccccat tgagttatat attctacttc tgtaactttc atatcatatt cattaagaat
    41641 tgcaatcatt tcttcatctg taacacctgc attttttgca tcaatataat tttcagcacg
    41701 caatccaata ccatcaaacc cagcttcttt tgcaatacga actctatcac ggaatgaaac
    41761 ttctgttccc aatgtataag aactaattgt aattggaata ttaagatttt tttgattatt
    41821 catagcttaa atttgccccc tttattttct ttataattaa tagtattttt gattttatat
    41881 ttttatttat cctactagta gtattatttt accttaaaaa taaaagtatt ttttgatttc
    41941 tatttatcta gattttataa atttattgta tcacgagact ttactaataa caaattgata
    42001 atttcctatt aattcataga ttttgtttat agattttatt tataagataa ttcttgtatt
    42061 tttctattag gtcgtataaa tatatttatc ttataattca gacaaaaaac gataaatttt
    42121 tttaaaagct tttattctta ctctataatc atatataata aaaatgtaaa aatatcttaa
    42181 aggttaactt ctacaaatat ataaataaaa atacctatga aaggatgaac aaaaattgaa
    42241 tttatatcac ttacgctatt ttgttacatt ggcacattta gaacactata caaaagcggc
    42301 agaaaattta tctataacac aaccaagctt aagtcatgct atttctttac tagaaaatga
    42361 acttggggtg gctctatttg aaaaagaagg tagaaatata gtccttacta agtatggaaa
    42421 aatattttta aaagatgtgg aaaaatcatt agaaatttta gattcaagtg taaaatcatt
    42481 aaaaataact ggtactggtg aaggacaaat agacttagct tttcttagaa cacttggtac
    42541 tgattttatc ccagacatag tgcacaaatt tttaaaatct aatcctgcta aatcaataga
    42601 ttttaaattt catactggtg taactactga cattattcaa ggtcttaaag aaagaaaata
    42661 tgatattgca ttttgttcga aacttgaaaa agaaaaggga attgaattta tacctgttgc
    42721 caaacaagat ttagtactaa ttgtaccata tagtcatcca ctagctgcaa aggatactat
    42781 agatttaaaa gaaaccatac cttatcctca aatagtattt aatcagagaa gtggtcttag
    42841 atatataatt gatgatatgt ttaaaaaaat aaatcaacag cctaatatag tctatgaagt
    42901 agaggaagac caagtaattg ctggattagt tgcaaaaaat ttcggaattg ctgtagtccc
    42961 aaatatgaat atgcttagct ttacaaaagt aaaagtaatt cagattattc acccaagttg
    43021 ggaaagaaac ttttacttag catttataaa agatagatat ttgcctcctg caattaaaaa
    43081 ctttaaaaac tttgtcatta aaaacgctca attataattt attaataaag gggttatttt
    43141 taaatatcct cttttattct ttttataaaa taaaaaaatc tatactttta aaagtataga
    43201 ttcctaactg acagtcggca tccgagtctc agtaattatc gttatacaac agcaactgga
    43261 ttcagttcct gaataactag gttacttaca ttatatcaga ttttttaaaa tttgtcaatt
    43321 gtatctaacg cattttttca agccatggtc caacaggctc tacaatagga acttctttaa
    43381 atccccaatt tcttatatca ttcacactcg ttggagtata tattttgttt ctgacagatt
    43441 tgaatatttt gtttttttct ccatattgca tacactttgg attagcttct attaaccctc
    43501 ttcttgctct gctaagagga ttacataaaa tatctgctat ttctaaacct tctctatagt
    43561 cagcatcttc ttttttggca attataaaac ccttaacctt atctcttaat tcttcatcta
    43621 tatctaagta tattgttcca ttattaaata catcaaaaaa cgccttttgt acttttaagt
    43681 ttgagacatc atcccttgac tctataacta ttcgtgcaga ttctacagtt tcattattta
    43741 caaatgaata aaaattctga agaacatgta taaaagccac aacatacggt tcctttgaag
    43801 gtgcataata tttctttaat ctagctttat ctactgttac tgatattata gtacactcta
    43861 atctagatag aaataaaggc aactcatcat agaataactt aatctgtgaa tcatcaaact
    43921 tctcaaatgc tcttgatttt cttgatatat ctgtcaaatg tattcctatg ttactggttc
    43981 caaaacaata ctctttaaat gcatccattt ctttcctcaa agaacataca taatcgcctt
    44041 gacttactgc atatttatat tcaaaaatta ctcctgtcaa tgtaaatggg tcttcatgat
    44101 ttatatcagc tcttccactt tcatcaataa acattatata ttttttcttt ataatcttac
    44161 tcaccctctt aacatatgat gatagcatct atattcattt tatatgagtt ttaaaaatat
    44221 tccaagattt ttatataact taaacttaat tttatactaa aaaattgaga tgtaaaacaa
    44281 tcaagctttt attgattgaa tttcacatct caattataat tatttttcaa tatatatttt
    44341 tactattttg caagaatatc cattaattta tccattacta tataagatac tccgcctcct
    44401 atttgataag gagtttcaac ttttttattt gcaaatactc tttgttgctc tgatgataat
    44461 cctgaattat ccattaaaac tattggtgaa tgtaatttta cagctaatgg tccagctgat
    44521 aaagcatcta ctaaagcatc tgatttacta actaatacag cctgtaaatc agtatctcca
    44581 tagaattttt ctatcacttt ggcattagta tctactctac tatctccata tattctattt
    44641 cctgaaatat cttcagtagt tatatcattc atttttgcta ttactgaatc gttaattgca
    44701 cttggtccac ctataaagta tgcattttct aattttcttt ctgttagcca tttataagat
    44761 tcttctgtaa ttccatcttt attgactaat attataggtt gtttttcttc cccagcttta
    44821 gaagctacag ataaagcatc tgcctcccca tttccagaaa ccatatatgc agtttttatt
    44881 tcttctcgat ttccaagttc ttcagctatt cttgtagcag tttgatatct atcttgacct
    44941 gctattctct ttgtttctgt gttgaaagta gtttttattt cttgctctaa tttagaactt
    45001 attgcatttt ctccacctat caagattact gttttaggtg ctaataactt catttcttca
    45061 acagtttcag ttggtaaatt agctgtatta gtaagtagta ttgttgagtc atagctactt
    45121 gctaaaggag ttgctgttat accatcagct attgcattac catttactaa tattacagta
    45181 tctgaactat cagcattcca gtttccaact gaacttatct ttttagctgt atcaaatcta
    45241 tttgcaccta taattgtatc ccatgtagga tttatagttc catcttcatt aaaagtataa
    45301 tctttcccat ctattttttg agaaccagtt agcatctttc catctttgtc taaatagtaa
    45361 gacttaccat ctatttgttg ccatcctgtc tgcattattc ctgttttgtc aaagtaatac
    45421 ttattaccat ctatttcttg ccatcctgtt actgctaaac catcagatcc tagatagtat
    45481 ttctttccat tcttttcttg ccatcctgtt tgcattactc catctgagtt aaagtaataa
    45541 gtttttccgt ctattacttt ccatccagat actcttgctc catcagttcc taaataatat
    45601 tttttgttat taattgtttt ccatcctgtt tgcattactc ctgaagcatc aaagtaatac
    45661 atttttccat ttacttttag ccaactattc ttttggtatg ttccatcaga ttttacataa
    45721 tacttcttac cattttctgt tttccatcct gtttgattta gatttatctt atattttgcc
    45781 gctatcttta catagctgtc gttactataa tctataatta catctgaacc tacaggaact
    45841 tggtcaaata accatctaac atctttattg tgcattctta tacatccacc agaaatatgc
    45901 tttcctatag aactctcatt attatttcca tgtattccat atgtatctcc ataagttcct
    45961 tttaatgcta atcccatcca tctatctcct aatggatttc ttggacttcc tccaggtata
    46021 ttacctttat aatatggtct attttttatc ttgttaacta cttttgtttt ccctgttggt
    46081 gtttctgacc cctttttacc tgttgcaact ctaaattctt ttacaagttt attatttaca
    46141 aaatatccta gagtattttt tcttgaattt actataatca catgtttact ggctgcgctt
    46201 gattctggta cgccacatgc aaatactaaa actaaagtca gtgctagtac taaatacttt
    46261 tttagacttt ttttcactat aacttccccc tcttttagaa acattactac atgtgtctaa
    46321 ttataacata aaattaccaa taccttatat ttacaaattt gttacattta tacatataag
    46381 tatgtattct actcttcata cccattagga ttcatacttt gccatctcca tgaatcttca
    46441 cacatctctt caagttcata cttagctttc catccaagct ctttttctgc ctttgaagaa
    46501 tctgcataac acatggctac atctccagcc cttcttccta caatcttata tggtatttct
    46561 tttccacttg ctttagaaaa tgcttttact aaatcaagaa cactataccc ctttccagtt
    46621 cctaaattat aaacaacaag tcctggattt tcttctaatt tttgtaatgc ttttacatga
    46681 ccagcagcta aatctaatac atgtatatag tctctaactc cagttccatc atgtgttgga
    46741 tagtcattac cataaacact caattccttc aatttaccta ctgctatttt tgttatataa
    46801 ggcattagat tgctcggaac tccatttggt tcttcaccta ttctaccact tttatgagca
    46861 ccgactggat taaagtatct taaaagagct atatccaatg acttatctgc ttttgatata
    46921 tctactaaca tctgctctat cataagttta gttcttccat atggattggt tacagaaagt
    46981 ggaaaatcct ctaatatagg acaagtatgt gggtctccat atacagtagc tgaagaacta
    47041 aatacaaact ttttaacacc atattctctc attaattcaa ataaatttaa ggtacttatt
    47101 agattattgc tgtaatattc aattggtttt tctactgatt caccaactgc ttttaaagct
    47161 gcaaagtgta taattgattc aatattattt tctttaaata caacatgcat ttcatcttta
    47221 tttctgatat caatattata aaattttact ggttttttag ataattcctt gattctatca
    47281 accactattg agttgctatt acttaagtta tcaactataa caacttcata acctgattct
    47341 aaaagttcta ttgctgtatg gcttcctata tatcctgctc ctccagctac taaaactgcc
    47401 attgtaatta cctcttttct aatatttatt tttcacttac tttttttctc atatagtcca
    47461 ttaaatcatc ttttaaattt tctctcttta gagcaaagtc tattgttgcc tctaaaaaac
    47521 caattttatc tcccacatca tatcttctac cttcaaagtt ataagcataa atagcctctt
    47581 gttttccaag agtttgaagt gcatctgtca gttgtatctc tccaccttta ccaggtgtct
    47641 gtttctctaa tatgctaaat attgcaggag ttattatata tcttccaagt atagctatat
    47701 cagatggagc ttcttcaatt gcaggttttt caaccatatc tttaacttta tatactctat
    47761 cttcgatatg ttttacatcc aatataccat atttattagt atcttcttta gctatctttt
    47821 gaacacctaa tacagttgtt ttatactcat tataagtatc tattaattgt tttaagcacg
    47881 gaacatctga atctactata tcatcaccta ataatacggc aaaaggttca tcacctataa
    47941 aactttttgc acagtaaatt gcatgtccaa gaccttttgg ctctttttgt cttatataat
    48001 gaatatttac catatttgat atgtctctta ccatttctaa catctctgtc ttaccttttt
    48061 gctctagttc taactctaat tcaactgatt tatcaaaatg atcttctata gattttttat
    48121 ttctacctgt tattataaga atttcttcaa ttcccgattc tatagcttct tctattatat
    48181 actgtaaagt tggtttatct actataggaa gcatttcttt gggctgtgat tttgttgctg
    48241 gtaaaaatct agttcctagc cctgctgctg gtattattgc ttttttaact gtcatctgca
    48301 ttttttcacc cttcttcgta aattttctat tgtaccaaat taatatacca tatttatact
    48361 ttttcttcaa actctatatt atcccaatat ttaatgctat aagataatat aaggtagatg
    48421 aaatttcatc tacctttagt tttataagtt aatattgtat tgtttatatt ttatccaaaa
    48481 cttatacagg tactaaattt catctaagat gccttttata tcactatcta tatcttcatc
    48541 tagataagaa tctaaatctt ctaagtcaac ttctagttct tgatatgtca tatcaacact
    48601 gacatcctca tctatatcca tttctgatat taattctcct aaaatactat ttccatcaga
    48661 atctaaacca ctatctatat cttcatctat atagttttca tttaaaattt catctaaatc
    48721 aatctcgtaa taaacttcat tatttttttc atcccctgag tccaatccta agaactcata
    48781 gttaaaagtc caaacattgt atttacttga catactttat tcctcctgtg aaaaacatat
    48841 tttcatctag tttattggtt ccataatcaa cagagttata tattttttca attatgtctt
    48901 ttcttctttc ttttgtacta ttatttaatg tcaattgttt aaatacatat gtatttgtta
    48961 ttctctcgaa taatatttct tttatactat catcatcaat atttctatag tttttccaca
    49021 ataactcaaa taacttaaac atttccctac tagtttcatc tacataataa ggatacatat
    49081 tttctactaa atggtttaat cttgatatgg cttgttttaa aaatacatca agacttgcac
    49141 tttcactttc ttttaacatt ctataattgt atttcttctt atcttctcct gaaattacaa
    49201 agatgatatt gtctaaactt ttttcaactt catttaaata actgcttata ttatatgata
    49261 aatcagacaa tagattttta atctgcttaa acacttgtac atcaagttta gtattatact
    49321 tttcaaacaa atctatttct tgattttcta atattcttgg catatatgct gacaataaat
    49381 ctaaattgtt tctttgttct tgtatttgct tataaagtga atttataact tctattctta
    49441 tttcatcatt taactctttt tctaaaatct tatcaaattc agatttcata tagtaaatat
    49501 ttccaaagaa attaaatatt atcatatcat tcatagcttt agaccaattc ttatatatca
    49561 cttcaataga attttcttta agtagaggtt gctttgcata tataaataca tcttgcataa
    49621 gtttttgaac catactttta cttaagttta aaagtacttt ttgattatta aattttattt
    49681 ccgtttctac aaaattagaa ttttcgtttt caagttcttt attaattaca atgtctttta
    49741 tatcactatt ttttatagat atgatttctt tttgaaaaga ctttagaata gtcaagctat
    49801 cgaaatcttc ttgaataaaa aatggagcat gttttaatgt atatcccact atttcatttt
    49861 ctatatcttt taggtcatct atttgcataa tttctctatt tttatcattt atatgtaggt
    49921 taaatacatt tttattatca tataatatta tatcttctcc taaatttaac ttagaacaat
    49981 tatctttcgc tgactttaca atagtcttct tagatttctt atttataaaa attaattggt
    50041 cttgatattt tactaaaagc atgtttgtgt ttttataatc aaatccatct atatttcctg
    50101 atatcttgca gaatactatt tcacaatctt taggaagatt tcctattttt tggttatctt
    50161 taactctctc atttaaatca gatgggacta cactatctat attgttatta aatatagata
    50221 cagaccttac tataatcccc tctctttcca tatgaaagta tcccttcaat gacactcttt
    50281 tatcttctaa aatgtatctt tctatatcat caaaatttat ttcaaatcta tttttcccac
    50341 tgataaatat aaacttctca ttatctttat taattccacc catataaaac ttattgtcat
    50401 ctaaacttaa tatagtcata ttatccttta gatagaatat aaattctctt tgacttttgc
    50461 agattaaatc atattcatcc aaagttattt tcatagtcaa atttgctgta acatttttac
    50521 ttgaattttc actttttatg taaaaaggca agttatttcc atagacaatt atttgagaat
    50581 cttctaaaac tgcctctaat ttttctttat tgtctgaaaa actatatata tattttacac
    50641 ctgtatcctc attaacttca tctgatttgc tgattattat attccctaga tttgttatat
    50701 gaagcttttt atattctttt gagtatctac ttatgccact aagctcaaac ccatctgaaa
    50761 gctcatatat gattttttct cctaatttca acataccttc accacctaaa cagaattata
    50821 agtattttat aaaggtgaat aaaatgtctc aaaacaaata atattttttt taatactttt
    50881 tattctgaga catagtttct ccttttttat aatgctctaa gcaccttcaa ctatttcttc
    50941 ataaagttta tctaaatgtt taacatattc acgatatcca gatttgttct ttaactcact
    51001 tcttaaatct tcatattttt gtttaagttc ttcagcactc aaagaaggag ctgattcttt
    51061 taattcttct aacttataat catagtactt atcatacata gctatatatg tatcaataga
    51121 cttcttagct agttcattac atttttcttg tgcttctcca tattgagaat aatcacctat
    51181 ttttatttta tagtatccat tttcttgaat tattgttgaa gaaatacctt tagcttcata
    51241 ttcttttgct gtttcttttg ctgttttttc aactttaagt gaacctgcat aaacagtgta
    51301 atatacacct ttaccatctt tatatgcttc catttctttt gctttctttt cagcttgtgc
    51361 tttttcttga gcctcttttt cagcttttgc cttttcttct gcttcttttt tctctttttc
    51421 agcttgtgct tttttctctt cttcagttaa tttattgtta gcttgttgtt gagttgatga
    51481 ctttggaata ttctctttat catttttctt attgttgcct actgttataa aatatcctac
    51541 accaacaata accactataa ctactgctat aatagtttct tttaatctac tcttcttaga
    51601 aacaacctct tcatcatcta aagaatcttc tttatctgat acataatttt tcatttcttt
    51661 cttgttttct ctatatttgt ccttagaaga atttttagat tttttattac tattttcttt
    51721 ctttttaata ggtattacta ctgatttttc attttctaat ttttcttctt ttatttcttt
    51781 tgctttttta tcttctaagt ttttactttc tttttcaagc ttcgattcat tatttgaaga
    51841 tactttttca tctaagttat tatttattgg tttttctatt tttacactac gttcttcttc
    51901 tatatgttga cttggttctt cttgttttat ttctttcaat tcattttgct ctatttcttc
    51961 tgatttcact tgatgatttt caactggttt atctaaaatt atatctggag aaatatcatt
    52021 taaattctct tcttcttgtt cagcttcttc attgtctttt ttaataaatc caaataattt
    52081 agccttcttt ttactctttt tattttctgg ttcaattata tcttctttat tgctgtcgta
    52141 ctctttatct gtagtatctt tatcttctac aacgtcacct atatcttgat tattactatc
    52201 tacttcttct ttagtccctt cttcagcatc atcttctatt gaaatactac ttctaaagca
    52261 aatatcttta tctgcatttt ttatcatgta aatgtattct tcaatatcga tatctttatt
    52321 tcttctagtt ctttttgatg caatttcatg attttctaat tcactatagt tatcttttat
    52381 tagattctgt gctttattcc atgtatcttc actaatttct gttttatttt taattacata
    52441 gtccacaaat tccttaaaat tttcaggacc aaattctcca attatagtca gtctcattgc
    52501 accttctata aggtctctat ttcttctctt taaaaattct aatacaactg ttgcacaagc
    52561 aaaatcttta ataatttctt tgccaaaacc atatgcttca acagaatgaa gttcttctaa
    52621 tccacataac ttcttatatt cattgtgtat tgtttgagat atactttcat tatttaagct
    52681 atttaactta tctataaact tcgattctat atcatttgat tttgattcat gttttacttt
    52741 tgaattttta atttcattta gtagcatgtc attttctgaa ttatctttac ctaattgcaa
    52801 atcctcaatt tcagttgctt ttatttctac tttgttttgt tcgttattct cttccacatt
    52861 attaggtacc acatctttat tactagctaa tattttgttt acacagaata taatttctct
    52921 ttttaattct cttttcgcat ctgcttgatt tttaagaaat aaatctccac attctttctt
    52981 ttctaaactt atttttctaa gagatatatt aagaaggtct ttatataggt ttaaaacctt
    53041 ataatccttt tctaaacgtc ttcttctctc tgatagttcc attttatcat aagctaaaaa
    53101 actatttaaa tcattggctt ttagagagtc taatccctct ttcatagcct tatttacata
    53161 ctttctacat tttgctgtag ttaactctaa atctttttct aattcatcta tttcaggtat
    53221 gtacttatct actatccatt tgccaataag tggttctgta tttcttgcta atgtcttata
    53281 aaacaatata ttaaatttta aaagctctgc atattttgct tcattaaatt ctactttttc
    53341 aaatttcttt tccaaaacac catctagctt ttcatttatt ttagactctt gttttaaaaa
    53401 acttgctgtg acatttaaaa cagtgtttct tattatatta ttttcactca aaaccttcac
    53461 tccttaaatc aattatttta ttgtaatatt tacattgtgc aaagttgcta atttgattat
    53521 gatatctaaa taattattta ctaaatttgc tacatcttat atcatatcat attatttaca
    53581 tcattttact ttttcttttt atatctatct tatattatac catttttaat atctgtacta
    53641 acttatatta caatattcct caaaatttta aaagtagatt agacaaattt acaaataaaa
    53701 aaacatcagt ttaaactgat gtttttgact atcgaaataa ttaagcaagt ctataagcgg
    53761 agttctgtat tagataatca tctttctagg cctattgtca ccaataggct caagcgacct
    53821 acctaccgga gagtacgagc agcactcttt attcctatct tggtcttgct ccaggtgggg
    53881 tttacatagc caactagtcg cctagctgct ggtgagctct tacctcgcct ttccatcctt
    53941 accacaatag tggcggttta tttctgttgc actatcctta ggatcgctcc cactaggcgt
    54001 tacctagcac cctgctctat ggagctccga ctttcctcat gtaagattac atgcgattat
    54061 ctggcttact taatatttat tttacttagt tatgttaaca caaattcttt tacatgtcaa
    54121 agtaatatta tactaaaaat ttaaatttat tcaaaaatag tgtaatatag atatataaac
    54181 tacatttaac tcgaggtgat ctattgaaaa aattatatag aatagtaatt aacattatac
    54241 tagtattagt aatactttac agtggattta atatatactc aaaacttacc aaatacaatc
    54301 atgatactaa aatatcctca gaacttcaaa aaaaagaata taaaaaagag gatttatcaa
    54361 agattaacag tgattttaaa ttttggcttt ctgttgagaa tacaaatata aattatccag
    54421 ttgtacaatc taaagataat tcttactatc ttgacaaaga tttttataaa aaagattcta
    54481 tttctggtac actgtttatg gattatagaa ataaatctat tgatgacaaa aatatcataa
    54541 tatatggaca taatatgaaa aataaaacta tgttcaacaa cctaaataag tttaaagatg
    54601 ctgacttctt taaaaaaaat aataaaataa aaataacctt gaatggaaaa gaatttttat
    54661 atgatgtttt ttctgcttat attgtagaat ctgattatga ttatctaaaa acaaatttta
    54721 acaatgaatc tgattatcaa aattacataa atgatattac ttctaaatca ttgtataaat
    54781 ctcctattaa ggtaaatagc aatgataaaa tagttacact ttctacatgt acctatgaat
    54841 ttgatgatgc cagaatggtg attcatggta gattgattta aaactcacag acacagttta
    54901 aaacaataat tttaaactgt gtcatctttt atacctataa tttgtaaatt agaccactaa
    54961 aagtatttaa tacaaaataa caaatacatc aaacaataaa aaacaataaa aaaagactat
    55021 gctaaaaaca tagtctttac tggagctggt gataggaatc gaacctacaa cctgctgatt
    55081 acaagtcagc tgctctaccg ttgagccaca ccagcacacc tattttattg taaattagca
    55141 aaactaattt ttaaaagtta
//
LOCUS       DAEPHU010000019        54997 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 01A10CD0081
            SAMN05941466-rid12468953.denovo.019, whole genome shotgun sequence.
ACCESSION   DAEPHU010000019 DAEPHU010000000
VERSION     DAEPHU010000019.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941466
            Sequence Read Archive: SRR6291087
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 54997)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 54997)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068158.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 22:43:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,892
            CDSs (total)                      :: 3,805
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 87
            rRNAs                             :: 8, 1, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 55
            CDSs (without protein)            :: 55
            Pseudo Genes (ambiguous residues) :: 0 of 55
            Pseudo Genes (frameshifted)       :: 21 of 55
            Pseudo Genes (incomplete)         :: 28 of 55
            Pseudo Genes (internal stop)      :: 16 of 55
            Pseudo Genes (multiple problems)  :: 8 of 55
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..54997
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941466-rid12468953.denovo.019"
                     /strain="01A10CD0081"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            155..1435
                     /locus_tag="KR231_001226"
     CDS             155..1435
                     /locus_tag="KR231_001226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase"
                     /protein_id="HBH0003628.1"
                     /translation="MNILGLIVEYNPFHNGHIYHLSKSIEKTNATHTVAIMSGNFLQR
                     GEPALFDKYTRAKIAVENGVDLVIELPTLFACQSAEIFSHGAITILNSLNCINSICFG
                     SEEGNTEILYNIAEILANEPNEFKLLLKKYLDDGLLFPTARANALFDYIHQDKKNNFI
                     QNYSKEQLSKTLNSSNNILGIEYIKNLIHLNSSIKPFTISRVQSEYNSEEIESDICSA
                     TAIRTSLKENTDLFHLKNVIPEKTYNILNEKIDNGFLPMFDDFFFDILKTIILRDMDT
                     LKEYFEVNEGIENRIYKDIFTSEFLHELQLAIKSKRYTLTKIKRTLNNILLGIKKSDM
                     QLIKNIDTIPYIRILAFNDKGREILKEIKNKSEIKIINKFSNISFSLDDTIFKTLISY
                     DIKATNIYNSIYYKNNKDLVKGPMDFYTHPIYVK"
     gene            complement(1698..3089)
                     /locus_tag="KR231_001227"
                     /pseudo
     CDS             complement(1698..3089)
                     /locus_tag="KR231_001227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729521.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-binding oxidoreductase"
     gene            complement(3100..4320)
                     /locus_tag="KR231_001228"
     CDS             complement(3100..4320)
                     /locus_tag="KR231_001228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-binding protein"
                     /protein_id="HBH0003629.1"
                     /translation="MSKIVVNQDKITDLKRILEICPFGAIEEKSGIVEISAGCKMCKL
                     CVKSGPKGAFEFIESSKVQINKDEWRGIAVYVEHHNGNIHPVTYELIGKAREMASKIK
                     QPVYCVFVGKDIKDKCSNLISYGVDEVFVYDEDEFKDFRIEPYSKAIENFIDKIKPTI
                     VLVGGTTLGRSLAPRLAARFRTGLTADCTILDIQSNTDLDQIRPAFGGNIMAHINTPN
                     NRPQFATVRYKIFSAPEKIENTTGKITLCKVEKKELKSKIKVLSVKEKNKEVGLEEAE
                     VIVVASRAIKKQEDMEMIYKLADKLNAQVAGTRPVIEAGWIDAKKQIGLSGRTVKPKL
                     IITCGVSGAVQFVAGMQGADYIVAINKDDKAPILDVAHLALIGDIYDIIPKLIEKIEN
                     NKDNNQKYMASAAK"
     gene            complement(4334..5122)
                     /locus_tag="KR231_001229"
     CDS             complement(4334..5122)
                     /locus_tag="KR231_001229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003402402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="electron transfer flavoprotein subunit beta/FixA
                     family protein"
                     /protein_id="HBH0003630.1"
                     /translation="MEILTCIKQVPGTTSVEVDETTGVLKRDGVDSKMNPYDLYALET
                     ALRIKEDKKANLKVLSMGPPQAKKVIEESFMMGADEGALISDRRFGGADVLATSYTIS
                     QGIKKMGKVDLIICGKQTTDGDTAQVGPEVAEFLDIPHVTNVTKLIEVKDESIVVEID
                     MPNDLQVCEIEYPCLITVEKDIFQPRLPSFKLKLNTKDREIPVYSLDDFEDKNENNYG
                     LNGSPTQVVRIFPPKPNTDKNIVRGNADELSFALVNKLEELKLV"
     gene            complement(5139..6413)
                     /gene="larA"
                     /locus_tag="KR231_001230"
     CDS             complement(5139..6413)
                     /gene="larA"
                     /locus_tag="KR231_001230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nickel-dependent lactate racemase"
                     /protein_id="HBH0003631.1"
                     /translation="MVKLKVPYSKQGMILEIPDERFLGVLESKSDNYIEHKTQEEIVE
                     ESMNNPIGSNSLEELVKGKKNVVIITSDHTRPVPSRITMPIILRRIRNVNPEIDVKII
                     VATGFHRPSTREELIYKMGEEIVDNEDIVMHISTDDKSMCKVGILPSGGDLYINKLAY
                     EAELLIAEGFIEPHFFAGFSGGRKSVLPGIASAKTIMYNHCSDFIDSDNSRTGKLNNN
                     PIHEDMVYAAKVAKLAFILNVVIDKDKKIIASFAGDVEKAHTKGCRFVTELSKVNSIK
                     SDIVVTTNGGYPLDQNIYQSVKGMTAAEATCKDGGVIIMISACNDGHGGQSFYENVAN
                     ADSPKQLLDKIRSVDRVDTIPDQWEFQILARILSKYTVIMVTDKCNPEMIKKMHMKHA
                     FNFKEALEMANSIVGKESKVVVIPDGVSVIVK"
     gene            complement(6531..7244)
                     /locus_tag="KR231_001231"
     CDS             complement(6531..7244)
                     /locus_tag="KR231_001231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FadR family transcriptional regulator"
                     /protein_id="HBH0003632.1"
                     /translation="MFNSIASKKVYEQVIEQIQYKILNGELKKGDKLLSERELSEQMN
                     VSRTSIREAIRVLETMGVIESRQGEGNFICTNIEKTLIEPLSMIFKLNNGTLEDILEL
                     RIILEIEIAKLASKRITSSEVIELKHIIDEMRVETNKKDNNRVLVLLDQKFHSKLATL
                     SKNYLIQSLFMTASKLFDGFIEDAREKIIAEPFNENILLKQHEAIYNAVVENDVELAC
                     EKAKEHMDFISKNYRKNEN"
     gene            7369..8628
                     /locus_tag="KR231_001232"
     CDS             7369..8628
                     /locus_tag="KR231_001232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sporulation integral membrane protein YlbJ"
                     /protein_id="HBH0003633.1"
                     /translation="MKKNKIIAFFAPSIIVGVLVLGIILYPNEAIKSAREGFSIWSNV
                     LVPSLLPFIIGANLIVDLKIVDIIGFIINPITRFVFNVSGKSALAFAISTVSGYPVGV
                     SLASEFRSNGQISKYEAQRLVSFCSTSGPLFIIGSVGTGMFQNSNLGYLMILCHYLGT
                     ILVGLFFRNYGNENLPKTKLDLKTNIKNVINIRNSSGNGFFVLFGNAVFNGVNTLLTV
                     GGFVIVFSVVFKILSLFNVISLIASVIYLPLSFLGVSKELCQAFVSGLFEITIGCNKV
                     SSITSSPEILRASLASFLIGFSGLSILAQCCTFLSKTDIDLKLYILSKFAHGVLAAIF
                     IFILYPIANSAVLVSSFADTYNVIYNNLIWFYYLSYYDTILQIVVIIYLISAVFIAKK
                     HMKTLSTNGKLMRYKNTFFTKKFSRKK"
     gene            8908..9474
                     /locus_tag="KR231_001233"
     CDS             8908..9474
                     /locus_tag="KR231_001233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HBH0003634.1"
                     /translation="MATRPIEIDEYKKIMELLHTGFTYSENGVEKRFRKNPKVALALM
                     LEANLGLRISDILRLKIGNFKGNMLEINEKKTGKLQYRPVNKNIIESINEHARKYNLK
                     SNDYLVNIKTKAIQKQLRIICKHLNLYNISTHSFRKLYATTQFEKSNNNLELVKELLN
                     HSSVATTQRYIRVTQQAINEASENFFIG"
     gene            complement(9675..10880)
                     /locus_tag="KR231_001234"
     CDS             complement(9675..10880)
                     /locus_tag="KR231_001234"
                     /EC_number="1.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine dehydrogenase"
                     /protein_id="HBH0003635.1"
                     /translation="MKIAILGYGTVGSGLIDLIENNTSKRDIEVVGILVKNKEKHKYK
                     KYFDKITTDIEDIFDKDIDILVEVIGGLNPAFDYVTRALNKKIHVVTTNKDLLAEKGS
                     DLIELANLNNVSIKFEASVAGGIPVLKPLIESLEGNNIKSINAILNGTCNFILSKMYD
                     ENLPYDVALKQAQELGFAEVNPDADVLGYDSARKLSILSTLSYGKIVYWKDLLLEGIT
                     SIDEKDIEYAKKLNCKIKLVARSKYESGEVSGFVRPALVDNNNMLSKIDNEFNVVILV
                     GDSVGELSFVGKGAGRGATGSAVYADIIDIIDNRSSNIKSFSKGKLDLSGLIEDECSA
                     VVRFGGYNNKDGILECLDKYVDSYDIIDDEELAIFVSAKSEHEIDRVLEIVKRNNYSE
                     SAKKLLKID"
     regulatory      complement(10983..11089)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00162"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="SAM riboswitch class I; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="S-adenosylmethionine"
                     /db_xref="RFAM:RF00162"
     gene            complement(11181..11549)
                     /locus_tag="KR231_001235"
     CDS             complement(11181..11549)
                     /locus_tag="KR231_001235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhbY family RNA-binding protein"
                     /protein_id="HBH0003636.1"
                     /translation="MLKGKQRAYLRSLANTLKPTTQIGKEGVTESFLEQLDGMLRTRE
                     LVKVTILENAGLDTKETANAVCEALRAEFVQAIGFKFTIYKRNIEEPKILFPGHEQAK
                     AKTKNNNVTKKGKPTKRAVR"
     gene            complement(11601..12878)
                     /gene="obgE"
                     /locus_tag="KR231_001236"
     CDS             complement(11601..12878)
                     /gene="obgE"
                     /locus_tag="KR231_001236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000469293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase ObgE"
                     /protein_id="HBH0003637.1"
                     /translation="MFIDKARIFVKAGNGGNGSVAFRREKYVPAGGPDGGDGGRGASI
                     IFEVDLGLRTLMDFKYQKKYQAQNGGDGSKGKRAGKNGENLVLKVPAGTVIRDEATGL
                     VLADLKKEGDTAIVAKGGIGGKGNQHFANAVRQAPAFAKSGTDGEERWITLELKMIAD
                     VGLLGFPNVGKSTFLSVVTKAKPKIANYHFTTLTPNLGVVQTKFGDSFVLADIPGIIE
                     GASEGIGLGHEFLRHVERTKVLIHIVDISGLEGRDPIEDFDKINDELKLYNEKLSKRP
                     QVVVANKFDILEDESKFEKFKSELEGRGYTVFKMSAATRQGIDEVIAYVSKMLKEVED
                     VELVSEEEMYRPELDIGTEEELSIDIEDGVYVVTGKALRRIMYSVNFDDMESLQYFQK
                     AMESQGVFDRLREMGIEDGDVVKIYELEFEFYN"
     gene            complement(12989..13279)
                     /gene="rpmA"
                     /locus_tag="KR231_001237"
     CDS             complement(12989..13279)
                     /gene="rpmA"
                     /locus_tag="KR231_001237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L27"
                     /protein_id="HBH0003638.1"
                     /translation="MLNMNLQLLASKKGVGSSKNGRDSISKRLGVKRFDGQLVTAGSI
                     IVRQRGTKIHPGTNVGKGSDDTLFALVDGTVKFERKDKKRKKVSIYPVAIAE"
     gene            complement(13293..13610)
                     /locus_tag="KR231_001238"
     CDS             complement(13293..13610)
                     /locus_tag="KR231_001238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal-processing cysteine protease Prp"
                     /protein_id="HBH0003639.1"
                     /translation="MIKVKYYYNDDFLLQGFCLKGHADFAEIGYDIVCAAVTSNAIAV
                     INSLDKLQKIEFEKVVGEEGHIECIVKDTHVKDAQLLLNHFQLAVKEIKREYPKNIKI
                     LKK"
     gene            complement(13625..13936)
                     /gene="rplU"
                     /locus_tag="KR231_001239"
     CDS             complement(13625..13936)
                     /gene="rplU"
                     /locus_tag="KR231_001239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012063435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L21"
                     /protein_id="HBH0003640.1"
                     /translation="MYAIVKTGGKQYKVSEGDVLFVEKLEANAGDVVTLNEVLACSKD
                     GELKLGSPVVEGASVQAKVVEQGKAKKVIVFKYKAKKDYRRKQGHRQSYTKIVVEKIN
                     A"
     gene            complement(14037..15458)
                     /locus_tag="KR231_001240"
     CDS             complement(14037..15458)
                     /locus_tag="KR231_001240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rne/Rng family ribonuclease"
                     /protein_id="HBH0003641.1"
                     /translation="MKKIVIESLIGSQKTAVLEDERLTELFVEDNLNKKTVSNIYRGI
                     VKKVIPGIEACFVDIGFKKLAYLQLKKGSTIKSGQDILVQINKEEIGTKGAKLNTEIS
                     ISGRYIVYIPSNDRTTISNKITDEKERFRLKKITKAVNKENLGLIIRTEAQGCTHDEI
                     KKDIEELKLKYENILKEYKLGIGPKLLYKSLDFATKYVKDNVNDDIESIITNSYDKYS
                     ELKSILRGIDKTYVDKLCLEENRDVFDLYRIESKIEKLLNKKVWLKSGGYLIIEKTEA
                     LTVIDVNTGKFIGTGKLDETVYKTNLEAAKEIVRQLRIRDIAGIIIIDFIDMHKKKHQ
                     KEILHILEEEFNKDKRKAEVLGMTKLGLVEVARRREKESIDKYYLMSCPCCDGEQTIK
                     SVHYILDSIEKEIMRISEHTVYKNIMVEFNDFIFEQIKEYYMDIIDKIGEKYNIKISL
                     NANSTLKHNKTNVIFDKIVDNKM"
     gene            complement(15476..16177)
                     /locus_tag="KR231_001241"
     CDS             complement(15476..16177)
                     /locus_tag="KR231_001241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2344 domain-containing protein"
                     /protein_id="HBH0003642.1"
                     /translation="MSKIIRVKFKKEGDMIYISHLDLQRLLQRAFRRAEINLSHSQGF
                     NPHPKMSYGNALALGTESQGEYVDIEIEEDDLSVEEFLNKVSIQLPDGIDFIKAKEID
                     RQTPSLSSVIDYGEYLFNIDLKRPMTKEFVKRKVIDFMNNKEIIITKKNKKGKMVEVD
                     IRPMIRTFDVLNLEDEHITLTATIATGSKTNLNTNILIPKILEMFELDIDPLDVDILR
                     RDLYVLEDGELVTPM"
     gene            complement(16179..18023)
                     /locus_tag="KR231_001242"
     CDS             complement(16179..18023)
                     /locus_tag="KR231_001242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428473.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR03960 family B12-binding radical SAM
                     protein"
                     /protein_id="HBH0003643.1"
                     /translation="MNKVDLKKILKKVEKPARYLGNEINSIHKDTSNSELIRYAHCFP
                     DLYEVGMSHLGSHILYDVINKDEDVFCERVYSPAVDMENIMREKSIPLFALESREPIT
                     NFDFVTFTLQYELSYTNILNILDLANIPILKEERTLEDPFIMVGGPCAYNSEPLADFV
                     DVVILGEGEEVNLEVVNEYKEWKKNKTTREDFLYKISSIEGVYIPSFYDVKYNEDGTV
                     QSVTPNREGITKNPTKRIIKDVETVDYPEKLIVPYIDTVHDRIVLELFRGCTRGCRFC
                     QAGMIYRPIREKSVKRLKEILDKLVKNTGYDEISLSSLSTSDYSKLSELTDYLVDEYA
                     SNNIGISLPSLRLDNFSMEIADKIQQVRKSGLTFAPEAGTQRLRDVINKGVTEEDLEN
                     ATERAFEMGWNSVKLYFMIGLPTETYEDLDGIAKLAYKVIDIYRKVNGGKLKRSFSVT
                     VSTSTFVPKPFTPFQWHGQDTTEEVINKQRHLVNKLRNNNIKYNYHDSKTSLMEAVVA
                     RGDRRIGKVIYDAFRLGAKFDGWAEHFNLDIWKEAMEKNNLSIDFYAHRNRNYEEVFP
                     WDHIDVGISKKFLIREDENAKKEKITSDCRHNCNGCGINIHDIGRGLC"
     gene            18342..19535
                     /locus_tag="KR231_001243"
     CDS             18342..19535
                     /locus_tag="KR231_001243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FprA family A-type flavoprotein"
                     /protein_id="HBH0003644.1"
                     /translation="MSKVFEVKKDIYFTGVVDEGLKVFDIIMETEFGTTYNSYLIKDE
                     KTVLFDTVKANFKDEFLSNLSEVTDIAKIDYVVIHHTEPDHAGSLKYLLDINPNIEVY
                     CTKAAKLYLDGQINRPFNCHVIKDGEILNIGKRNLRFITAPFLHWVDTMFTYIEEDKT
                     LLTCDAFGCHFASVDAEVVNSEDYLKSAKHYYDCIVKPFAKHVLSAVDKVVGLNIEFD
                     TILTSHGPMLTKDPMAAVKRYVEWSTEAVNTTNQNQVSIFYLSAYSNTLEMAKKIKEG
                     LDKEGAKAELYDLEDMTLTEMHDTLVVSKVILLGSPTINKTMVKPMWDLFSVIDPMAN
                     QGKIAGVFGSFGWSGEGITMAETLLKSMSFKMPVESLKKKFFPSEETLKECMAFGAEF
                     AKLVK"
     gene            complement(19747..20829)
                     /locus_tag="KR231_001244"
     CDS             complement(19747..20829)
                     /locus_tag="KR231_001244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861129.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transglutaminase domain-containing protein"
                     /protein_id="HBH0003645.1"
                     /translation="MKKIRKLATKLLIAMMVLTSCMSVTVYGMTAKDVTAKTPKSYVA
                     GTNSIYGPKLSQAQLNSVAQATADFMNKKITKNMTTDAKIRVAYNHIKNNTTYVNWNA
                     AEGANTAYTLVTKKGACSGMCRSLKALCDAMGIECYYVHSTTNDHQWNLIRFEDGRLY
                     HVDIDANKSAGADIIYKSLTHPLPFDKKAYPAVGEVVKTQNPTPTVKKPTPAKPSAPV
                     GPGNHTMIADQQGAILDEVYGNNLRPKIEMYEGVPCSLINSSINTIKFTSKNSNLDPS
                     KHTVTVIGFMNTPYGMVALAPDGVPDEYPFEYDKPFSLDFTGKNLSAAELSKKCKENN
                     VIIKVEIGETASNSGRGMVAYARYVN"
     gene            complement(21393..22184)
                     /locus_tag="KR231_001245"
     CDS             complement(21393..22184)
                     /locus_tag="KR231_001245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0003646.1"
                     /translation="MKLIDEYLDKLYKKCDNKSTIELKQEMRCHLIESANEFKLEGLD
                     EEEACKKAIERFDDGDEMQYELCNIIKELSLSLDRHKSIVMGFKKVLGYISIIAFLIS
                     GFMWYYNNSLQHNMYNLGKELDGEIKQLAERHDMTKIGEYKLELEKILDKDKYSKVKA
                     LRLYVIDMKDGNTNLSSSGLNANMVYEREADYNNISNFIQHLGYNGKDFLDKNGNIVN
                     PDIFLEYFFYFESEMLIPVAFAFGLLCIIAYFILRFKISLIKNNN"
     gene            complement(22188..22517)
                     /locus_tag="KR231_001246"
     CDS             complement(22188..22517)
                     /locus_tag="KR231_001246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBH0003647.1"
                     /translation="MQLNKEVLKGYIDILIVSILEKKDCYGYEIAKQVRERSEFELKE
                     GTMYLALKRMESKNLIKSYYSNEQSSGGRRKYYNLTNEGKDFLEIKKQEWRFIKKVMN
                     QFLGEVD"
     gene            complement(23002..23415)
                     /locus_tag="KR231_001247"
     CDS             complement(23002..23415)
                     /locus_tag="KR231_001247"
                     /EC_number="4.2.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylglyoxal synthase"
                     /protein_id="HBH0003648.1"
                     /translation="MNIALVAHDQMKNTMVGFCIGYESILKKYGLYATGTTGKRIMDE
                     TELNINRLASGPLGGDQQIGSLIVTQEIDLVIFLRDPLTSQAHETDIQALIRLCDVYH
                     VPIATNLASAEIFIKALDRGELSWREVRKSKSQRI"
     gene            complement(23456..24586)
                     /gene="rodA"
                     /locus_tag="KR231_001248"
     CDS             complement(23456..24586)
                     /gene="rodA"
                     /locus_tag="KR231_001248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein RodA"
                     /protein_id="HBH0003649.1"
                     /translation="MKKININYKSTIKLIKQLDWKLIVTVLAIFIFGLVILSSATHAN
                     STGSYNQLIKQGLAFVLGIGMIIVILFFDYNLLGRYYKALYIISLILLAIVLLPGIGT
                     VKGGARSWINLGPLDLQTSEIVKLTFVLSYAKILESKKDKLNTLKEVMPVVVYSLPFI
                     GLLIAQPDLGTGIVFCCMIFAMLFTAGLSSKLIKRGIIILLVSMPLMYLMMADHQKVR
                     IEAFLNPEDVTLKGNYQVMQSLIAIGSGGVTGKGLYNGSQNQEDFLPVQDSDFIFAVV
                     GEELGVIGMAVLIILFMIFLLRLLAIARDAKDFYGTLIVVGVMGMFGYQIIQNIGMTV
                     ALIPVTGVTLPFVSYGGSSLLTSLANLGLVLNVCMRRKKINF"
     gene            complement(24671..24955)
                     /gene="minE"
                     /locus_tag="KR231_001249"
     CDS             complement(24671..24955)
                     /gene="minE"
                     /locus_tag="KR231_001249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division topological specificity factor
                     MinE"
                     /protein_id="HBH0003650.1"
                     /translation="MLDLFRVFSNEAKTSKSVAKERLKLVLVHDRVDCSPQLLEMIKT
                     DILKVIANYAEIEDDGLEIKMSKCRGEHDDKPVSALVANIPLKNIKDRCM"
     gene            complement(24973..25770)
                     /gene="minD"
                     /locus_tag="KR231_001250"
     CDS             complement(24973..25770)
                     /gene="minD"
                     /locus_tag="KR231_001250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septum site-determining protein MinD"
                     /protein_id="HBH0003651.1"
                     /translation="MSEVIVITSGKGGVGKTTTAANLGTALSLENKKTVVVDADIGLR
                     NLDVVMGLENRIVYDIVDVVEGTCRLKQALIKDKRFDNLYLLPAAQTRDKNAVSVEQM
                     IDLCEKLKESFEYIIIDCPAGIEQGFKNAVAGADRAIVVTNPEISAVRDADRIIGLLE
                     ANEIKEIRLVINRIRNDMVKRGDMMDKQDIIEILAIDLLGLVPDDESIIISTNKGEPA
                     ILDSKSLAGQAYKNIAKRILNEEVPLLDLEVEDGFFGRLKKMFSMAK"
     gene            complement(25794..26477)
                     /locus_tag="KR231_001251"
     CDS             complement(25794..26477)
                     /locus_tag="KR231_001251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septum site-determining protein MinC"
                     /protein_id="HBH0003652.1"
                     /translation="MSLREICSQELVEFKGNKRGIIVNIKREAPFEEIQEKIINKLEA
                     YVGFFNGAKISKINSDCLTDMEILELKEGITSRFDVEFVEDQKIEENSNFPTKYVNTL
                     RSGENIEFEGDVVILNDMKPGSKVLSKSNTVVMGDINAGAKVVAGGNVFVMGKIEGFV
                     HAGAEGNEFAYVVAGNLNPKILQIADNIAEAPDDEENYESESEISPEIAFVSNGRIVI
                     ESYLSKLDK"
     gene            complement(26575..29553)
                     /locus_tag="KR231_001252"
     CDS             complement(26575..29553)
                     /locus_tag="KR231_001252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein"
                     /protein_id="HBH0003653.1"
                     /translation="MEENKQVDRLKIIKIVMGVIFLAILVKIIYMTTFKYEYYNELAE
                     NKTYKKLAIEAPRGEIKDRYGRLLAGNKNLFTVQVSGNDINKKDANKHSRANEISLKL
                     INLLERNGEEYVDEFPIYVENGKYYYTYDRDIREYKSENGIPNDYNAKESFYYLVDKL
                     ISAGILSQEDKRLDATRLQAKLNENGYYPPILVSKWMFTAERDKRDWLASYKIKETKL
                     SAKEAFEKVRNSDALEIDKSLSDEDARKIMVVRDLIKSKGYSQYNPVTIAKDVGETTI
                     AQIEESAMDLVGVSIAVEPVRYYPNGSLASHMLGYVGKMPSTQIESYLQKGYETGDMV
                     GLAGVEKSNESRLRGTDGYKMVKVDALGRISKEIESKKPKSGDTVYLTLDKDLQEVSD
                     NALKQIIEVASKGGTFKSKFGDKPISAYAGKAQSAALIAIDVKNGEVLASSSYPNYDP
                     NKFAKGISTEDYKALQPKNPNDLLAGSPLLNLVTQGEFQPGSSFKMVTSMAALENGLD
                     PNFTINDPGVIMLGKKSFGDYVWNHGRGNHGMTNLYKAIQESCNIYMATIGTGKTWPD
                     GKSIGIDMNANKILEYAKLFGLDQNTGLQDEVEERAGKVPSTEDKLKSTQALLKSNLE
                     REMANDFVDITREKNPKEYEKRINEIVSWAAEKKTPGRVETMNRLKKLDVKEDRIEEV
                     ADLAVFSYFNFAKWSTADTFNLAIGQGENAYTPAQISRYVAAIANGGNLVELSVVDRA
                     VSSDYSSVKINDQKKVEKIPFKNPDNLKELTKGMKLVARQGTAKSAFADFPIDVAAKT
                     GTAEKSGKIPTDNEYEYLKSHMSSYNVNLNDAIKLADKMKAEKEKELSLAKEKEIKKK
                     LENKDLKDEERKKLEEELEDGVKVRLEDTDKVNSSYLRKAIKELNPKITDDQIDRFKQ
                     DYGSFTWTVAFAPADDPEIAVVCVIPQGDSSVFSLLPTREVIGTYMGLEPTNSKNDNK
                     TNDVNNSSDENINFESQINR"
     gene            complement(29565..30053)
                     /gene="mreD"
                     /locus_tag="KR231_001253"
     CDS             complement(29565..30053)
                     /gene="mreD"
                     /locus_tag="KR231_001253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreD"
                     /protein_id="HBH0003654.1"
                     /translation="MKKVLLCLLGIVLMTIENSITNYIDIFGISFNLVLIYVTIISLY
                     LDELEGGIIAAIIGLIKDITVGGIFGVNALILFIIAYAIGYMRDQLYKGSYIITFVLI
                     FIGSLIDSIVNIGTSSIIYQSYNISTLFVKGLLVAPIVNSLIGLVIYRLSKRAVLKLK
                     ED"
     gene            complement(30068..30961)
                     /gene="mreC"
                     /locus_tag="KR231_001254"
     CDS             complement(30068..30961)
                     /gene="mreC"
                     /locus_tag="KR231_001254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreC"
                     /protein_id="HBH0003655.1"
                     /translation="MALRFDKNKNEKKRINVKVIATGVVAITLIGIVGISIGKFSSGS
                     PVNLGVASDAITSVGKGINDGFSFIKNGFKDVANFKDNSKKVKKLEEENEKLKKNMIA
                     LNAKLDKTESLEELKKTLNFVQEEYKATSISASVVGKNDGNWYESFVIGAGKNSGVKK
                     ESIVMNGSGLVGIVYEVSNNYSKAISLLDSKASVSFKLAKDANAKGTITQNTTLDNKD
                     SYNSKGYLQGYMFDSSYNVIQGDIITTSGLGFFPDGIPIGEVEKVVDDKDKSLKYVVV
                     KPYVDFKNINDVVVIEPRNIG"
     gene            complement(30971..31981)
                     /locus_tag="KR231_001255"
     CDS             complement(30971..31981)
                     /locus_tag="KR231_001255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein"
                     /protein_id="HBH0003656.1"
                     /translation="MTKDMGIDLGTANTLVYIKGQGIVVREPSVVAIRDDSKEVLAVG
                     EEAKKMIGRTPGNIVAIRPMKDGVIADFDITQSMISYFIQKAADKKGVVSPRIAICVP
                     FGVTEVEKRAIEEAARQAGAKDAFLIEEPMAAAIGAGLKVEEPEGNMVVDIGGGTSEI
                     AVISLGGIVTAKSIRIGGDEFDESIVAYVKKEYNLMIGERTAENVKINIGSTFKDDEE
                     INMQIRGRDLISGLPKTIEICSTEVREALKEPVSSIVDAIKSTLERTPPELASDIMEN
                     GIMLTGGGALLRGLDKLITQETGMSVQIAETPLDCVALGTGKSVEDQEIFEKVLMMNT
                     KN"
     gene            complement(32102..32761)
                     /gene="radC"
                     /locus_tag="KR231_001256"
     CDS             complement(32102..32761)
                     /gene="radC"
                     /locus_tag="KR231_001256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadC"
                     /protein_id="HBH0003657.1"
                     /translation="MAPEERPREKMLAKGVKSLSNAELLAILLRTGNKNKNAIELANY
                     IINRDIQGIRHLEDMTIEELCNIDGIGLSKSTQIKAALELGSRVASFKPIKYKIRNPW
                     DIQRYYMDSLRYLKKEVFKAVLLNTKNEIISDVDVSIGTLSSSLVHPREVFKEAIRRS
                     ASKIIVMHNHPSGSVEPSREDKNITSRLIKCGEIIGIEIIDHIIIGDGLYFSFKENMI
                     I"
     gene            complement(32806..33390)
                     /gene="maf"
                     /locus_tag="KR231_001257"
     CDS             complement(32806..33390)
                     /gene="maf"
                     /locus_tag="KR231_001257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septum formation inhibitor Maf"
                     /protein_id="HBH0003658.1"
                     /translation="MNIILASASPRRKEILENTNVRFDIIKNEIDEIILEGETPKHLV
                     MRLAFEKSMSVASEHNEDVVIGADTVVVLDNAILGKPKDESCARDMLKRLSGREHQVI
                     TGISLINLCEDKKVIDYVISNVKFKTLSEQDIEDYLKTNESFDKAGAYGIQGYGALLV
                     EEIRGDYFNIVGLPISRLGDLLKKYFSINLFYGV"
     gene            complement(33610..34581)
                     /locus_tag="KR231_001258"
     CDS             complement(33610..34581)
                     /locus_tag="KR231_001258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RnfABCDGE type electron transport complex
                     subunit B"
                     /protein_id="HBH0003659.1"
                     /translation="MVILTAVLVLGIMGLIFGIVLDFASKKFAVEVDERVEAILGVLP
                     GANCGGCGFPGCGGLANAIVEGNAPVNGCPVGGADVGAKVGEIMGISAEAGEKQVAKV
                     ICKGTCSSAKDKYEYEGISDCRAANVLNSGAKMCKFGCLGLGTCKDACKFDAISIVDG
                     IAVIDEEKCVNCGKCKEVCPKGIIITKPESQEVVVECNSKEFGKAVKEKCTAGCIGCG
                     MCVKACKFDAIIFEDKIAKIDPNKCVGCMQCVAKCPTKVISGDITKKKKVTIDQELCV
                     GCTVCKKQCKFDAIEGELKEKHKVDADKCVGCHLCMEKCPKKAIKIL"
     gene            complement(34597..35172)
                     /gene="rsxA"
                     /locus_tag="KR231_001259"
     CDS             complement(34597..35172)
                     /gene="rsxA"
                     /locus_tag="KR231_001259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="electron transport complex subunit RsxA"
                     /protein_id="HBH0003660.1"
                     /translation="MNLILLFLSIVLVNNVITSQFLGICPFLGVSKKVDTAVGMGVAV
                     TFVLTLASIITYFIQILLVKTGTGFLQTIAFILVIASIVQFVEMVIQKMSPSLYQALG
                     VYLPLITTNCAVLGIALVNVQKSYNLVETIINGFGAGAGFTLAIVIFAGIRERLELAD
                     IPEAFKGFPITLISAGLMSIAFLGFTGLIKL"
     gene            complement(35187..35780)
                     /locus_tag="KR231_001260"
     CDS             complement(35187..35780)
                     /locus_tag="KR231_001260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="electron transport complex subunit E"
                     /protein_id="HBH0003661.1"
                     /translation="MNLAKVFKNGLIDENPTFVQVIGMCPTLAVTTSAINGIGMGLST
                     AAVLICANLVISLIRKITPDKIRIPIFIVVIATFVTIVGMLLKAYVPALDKALGIYIP
                     LIVVNCLILARAESFAFKTGAMPSIVDGVGQGLGFTVALTIIGAVRELLGNGSLFGMT
                     LFGASFQPVLIFILPPGAFLTLGFLFAGFNKLRSKKA"
     gene            complement(35793..36362)
                     /locus_tag="KR231_001261"
     CDS             complement(35793..36362)
                     /locus_tag="KR231_001261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RnfABCDGE type electron transport complex
                     subunit G"
                     /protein_id="HBH0003662.1"
                     /translation="MNSMVRLGGTLLAISAIAALALGATNQVTAPVIEQRNIQANNEL
                     RKAVLPEAKEFKEMKEDTYKGLGDGLIAEVYEGLDGSEVVGYTLKAKPSGYGGEIEVM
                     VGISSEGQVTGVDIGNMSETAGLGAKAKDDAFKGQYKGKTAEPLEVAKGSTTADNQIL
                     AISGATITSTAVTTGVNAAIDVFNSALNK"
     gene            complement(36362..37339)
                     /locus_tag="KR231_001262"
     CDS             complement(36362..37339)
                     /locus_tag="KR231_001262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RnfABCDGE type electron transport complex
                     subunit D"
                     /protein_id="HBH0003663.1"
                     /translation="MENKLIVSSSPHVRSNEDTSYIMKQVIIALLPAAVAGVYFFRLN
                     ALSAMFFCILGTVGTEFLYQKFTKQKSTIGDFSAVVTGLLLAFNVPASLPWWMCLVGG
                     IFAILVVKMVFGGIGCNFVNPALAARAFLLASFPVAMTAWTQPGVNWIGKNLDAVTTA
                     TPLSFLKNGAAGLADISSNGISLADMMIGNIGGCIGETSAILLLLGGVYLMYKGIINY
                     VIPVFYIATVFILTFLLGGFNITFAIYQLFAGGLMLGGFFMLTDYTTSPMTKKGQIIY
                     AVLAGLITTVIRMYGGYPEGVSYSILLVNCLAPLIDKFVRNRVFGEVAK"
     gene            complement(37362..38699)
                     /gene="rsxC"
                     /locus_tag="KR231_001263"
     CDS             complement(37362..38699)
                     /gene="rsxC"
                     /locus_tag="KR231_001263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="electron transport complex subunit RsxC"
                     /protein_id="HBH0003664.1"
                     /translation="MKLLTFKGGIHPPYRKEYSNTKALEKAQAPKIVYIPLQQHIGAP
                     AKPIVEVGDEVKFGQKIGEQQGFVSCNVHSSVSGKVIAIEQHEVPGGSAQCVVIENDF
                     KEELHESVQPKGQLEDLSKEDIVGIIKEAGIVGMGGATFPNHVKVSPPPDSKAEVVIL
                     NGAECEPYLTADHRLMVENPEDVVFGLRALMKVLDVKKGFIGIETNKPDAIEAIQNVA
                     KDYSEIEVVGLQVKYPQGAEKQLIYACTGKEVPSGGLPIAAGAVVDNVATAAQIAKSI
                     KTGMPLVERITTITGSCIKEPKNLITKVGTLVSEIIEQCGGFKEDKKIGKVIMGGPMM
                     GIAQYTTEIATNKGSSGILCLDEEESRTPDIQNCLRCGRCTDVCPSFLQPLFISAYSL
                     KDDYDTAEYHRAMDCIECGSCSFICPARRPLLQSIRSAKREIGAKRRKQAAQK"
     gene            complement(38915..39859)
                     /locus_tag="KR231_001264"
     CDS             complement(38915..39859)
                     /locus_tag="KR231_001264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0003665.1"
                     /translation="MNRRKTIYRGFNNNRHKIDLRKYVITIACLCLIGYYSYTKIKDS
                     KILEYVSAKIPFLNNSSDITYKDISDELNSIKKGKKSKSQTNSDDKQETNPEKAVNNT
                     KEPEEVKLATIEGWDMYTIQVAAIDNNDDLKKIQTSLVNNDIPFSVMEKDGVKKIQTY
                     SSFDENDVRKQISSVRKVFPDAFLSHLDAPMLSLEYTSNYAYIESISKELNKLITNFK
                     EESSFWSNAENNVDMEKYNTILTNRKAISQNISKEAEKIDYSEMRLFKDNLIEYVKNV
                     NEKIDTASKAANEEKYSVSKSLLLSSMQEYSMFINSIK"
     gene            complement(39970..41244)
                     /locus_tag="KR231_001265"
     CDS             complement(39970..41244)
                     /locus_tag="KR231_001265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SH3 domain-containing protein"
                     /protein_id="HBH0003666.1"
                     /translation="MKKAIAALGIGAVAVSVSSINASALEKGTVTASALNIRSGPSSD
                     CDKVAKLYKGKTVEILEKSNGWYKVRVSSSVVGWGSAKYISTSGSSEGTSSQNNPTSS
                     GTTISGNGKVNVSSRLNVRSGAGTNYSLVGKANNGDVVKLLEQSNGWYKIKLSNGVTG
                     WASSQYISKTSEDVGTNNSSNSNSTNNSDKKPSSEESIEGKNGKVTSAVSLNVRSGPG
                     TSYSIIGKLNGGDVVELKAKSNGWYKVKLSSGTIGWVSASYISETNEDTKEKPNSSSN
                     QNSQSNSNSKPSFTGNSDKSTAKGSTIVDFAYTLIGIPYQWGASGPDKFDCSGFTQYV
                     FKHSVGVSIPRVSREQANFGSAISMGNYAPGDLVYFDTDGDGTTNHVGIYVGNSKFIH
                     CSGTQTNPNKVKVDNLTSSYWSKVLLGARRFV"
     gene            complement(41376..41747)
                     /locus_tag="KR231_001266"
     CDS             complement(41376..41747)
                     /locus_tag="KR231_001266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HBH0003667.1"
                     /translation="MKFNFCHNNFNVTNLEKSLDFYKKALGLKEVKRKEAEDGSFILV
                     YLGDGITSHTLELTWLRDWDRPYNLGDNEFHLALEVEEFDEAKKLHKDLDCICFENES
                     MGIYFIADPDNYWIEILPKNH"
     gene            complement(41975..42574)
                     /locus_tag="KR231_001267"
     CDS             complement(41975..42574)
                     /locus_tag="KR231_001267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0003668.1"
                     /translation="MESRGYKEDLKKMILDMAHKELESYVSQKGAKKYFEGNLDKIIN
                     NNIKKFNQSIGLNRVYLKMLKKCAYQESVTSISRTIKKEALFKSKKELFAFSEYLKLD
                     INKRLSYNQILRKISRYIYYNRSSYAQKYVVFKRGDEEYLLEPEKIKDELISSYRSKT
                     REDMRSIAKLLDIEVEDDYNAEDIRKKVINYIIKEKLKS"
     gene            complement(42775..42987)
                     /locus_tag="KR231_001268"
     CDS             complement(42775..42987)
                     /locus_tag="KR231_001268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy-metal-associated domain-containing
                     protein"
                     /protein_id="HBH0003669.1"
                     /translation="MKKKLLVEGMSCGHCVNHLKTALTEDIDGIEVLDVDLENKCASV
                     DMKDDVSIEKLKEVIAELGFELKGIE"
     gene            complement(43060..44775)
                     /locus_tag="KR231_001269"
     CDS             complement(43060..44775)
                     /locus_tag="KR231_001269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HBH0003670.1"
                     /translation="MKRIKVLTVVLAITLMVAGCSNTKTKQSSSDSSLQSQSSIDAKY
                     INLTMVTPKTINPITNTDKSVGYIMNLVYDSLFTIDENYNVIPQLVKEYNIAQDGMSI
                     DIKLKDAKWHDGKNITSNDVNYTIGLIQKSADSPYNEFTKNIASVNIKSDKDFTIKFK
                     ARYAFSIDSLIFPIVSQNHLDSKDVNDKNNNMIGNGKYKIESYTEREGMVLSVNKDYY
                     EEVPKTMKNIKVGMVPNEDARTSMVMALDSDITNVTLNDLSKFQEKEFNITKYQGRDY
                     ECVLFNYNNPFFKDVNFRKAIAHSIDKDRIISEGYMDDATPVNFPLNSKSKYYNSEMK
                     DLEFNKDKAIECLAKVEYANVNSVNQNDNKVKNQKKSAKKNSKKLTPEEEAKAKKAEE
                     DRIKKEAEEKKNREKEEVKKSLSEMNLKIIVNRDNSERIKTANIINENLKAIGINSTV
                     NQLSDKDMENALNSKNYDLALVGWKLSIIPDASSIIASSGYTDDKLNGYMSALTSSTS
                     EIETKKAYKDVQTYIKDNATFISLAVRNNYIVSNSRLKGKITPNDFDVYEGISNLDIK
                     SNESN"
     gene            complement(44775..45329)
                     /locus_tag="KR231_001270"
     CDS             complement(44775..45329)
                     /locus_tag="KR231_001270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lytic transglycosylase domain-containing
                     protein"
                     /protein_id="HBH0003671.1"
                     /translation="MNSKKVLILSIFIILFGALLMESKVIHKFLYPKKYSEYVEKYSK
                     EFNLDENIVYSVIKAESKFNSSAVSKKEAKGLMQILDITRDWGAEELNLKNVDIFDPE
                     TNIRLGCWYLSKLYKEFGKLDLVIAAYNGGSGNVKKWLENNEYSKDGENLHDIPFKQT
                     SKYVEKVKNNYEHYNKIYGKKGKN"
     gene            complement(45322..45924)
                     /locus_tag="KR231_001271"
     CDS             complement(45322..45924)
                     /locus_tag="KR231_001271"
                     /EC_number="2.7.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dephospho-CoA kinase"
                     /protein_id="HBH0003672.1"
                     /translation="MLILGLTGGIGCGKSSLSNIFRNLNIPIVDADIISRKIFEDKLL
                     LEKVFVHFGQSIKNDDGTLNRKALGKIVFSDEEKLKELNNLTHPRIREKIISEIEKLR
                     KKGENIVVLDAAILVESGFLDMVDKLLVVTCKQEVQISRIQKRDNCSEQEALSRINSQ
                     MSQEEKSKYGDYIIDNSGTITELESKAHKFIEYMKENWRE"
     gene            complement(45933..48581)
                     /gene="polA"
                     /locus_tag="KR231_001272"
     CDS             complement(45933..48581)
                     /gene="polA"
                     /locus_tag="KR231_001272"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase I"
                     /protein_id="HBH0003673.1"
                     /translation="MEKKLIIIDGNSIINRAFYALPEMNNKEGLKTNAIYGFTTMLFK
                     MIDIYKPTHISVAFDRKAPTFRHLEYKDYKAGRKGMPDELAEQLQPLKDLLDKFRINR
                     LEIDGYEADDIIGTVSKKAEENGYKVYIVTGDKDAIQLASDNTTTLITKKGVGEVEEY
                     NFNSVIEKYEMTPTQFIDLKGLMGDKSDNIPGVPGIGEKTGIKLIKEFSSIENLIENT
                     DKLKGSVKKKIEENKEIAIQSKRLATIIRDVPIEVDLDSMIFGDYDKDELLDKFRYFG
                     FTSLLSRLVDLVDSDDTEHVEEKIEILKLKDIEKFIDEVNKKGQVILKTVRGQGNILE
                     KNIIYIFISVDGEKIYYVDSNEVSKLDSIFSNNEIKKYGYNLKDDYISLKPYNINLEN
                     MYFDITIAEYLIDSTSSTSYDCSAIAMKYLSKKVKSKEELLGKGVKSKNYEDLEFEDL
                     AEYMGQIICTVKETVPMMERSLMDMSMDGLFYHVEMPLVEVLGHMEYEGIKVDKSILD
                     ELSVEFKEIIATLEKEIYELSGEPFNINSPKQLGVILFEKLELPIIKKTKTGYSTNAD
                     VLEKLRDKHPIIDKITEYRQIVKLNSTYVEGLLNIINPESNRIHSSFNQTITTTGRIS
                     STEPNLQNIPIKMEMGRKIRKVFIADDNCKLVDADYSQVELRVLAHMSQDENMIEAFK
                     HHEDIHTKTASQVFNVPMEDVTSELRGAAKAVNFGIIYGKSDFGLADDLNIPVPKAKE
                     YIESYFAKYHKIKEFMDTTVEKASEDGYAVTILNRRRYIPEIKSSNFMERNRGKRFAM
                     NAPIQGSAADIIKIAMINVHKKLEENNLKSKLILQVHDELIVEAIDDEIDIVKKIVKE
                     EMENAVNMDVHLDVDLNVGSSWYETK"
     gene            48733..48820
                     /locus_tag="KR231_001273"
     tRNA            48733..48820
                     /locus_tag="KR231_001273"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:48767..48769,aa:Leu,seq:caa)
     gene            complement(49007..49450)
                     /locus_tag="KR231_001274"
     CDS             complement(49007..49450)
                     /locus_tag="KR231_001274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0003674.1"
                     /translation="MKKNMLYVGIIYFICGILLVLLATFTEFSFEAFIWGLSGAALGP
                     GVCMILQYMYWSKPERAVDYEEKIKNQRIEMNDERRIMLRDKAGRITNQIMCYVLVIL
                     IFIVSILSVFSVMVISKWVLVVLGLLILFQFICSVVVYNKLDKRL"
     gene            complement(49453..49650)
                     /locus_tag="KR231_001275"
     CDS             complement(49453..49650)
                     /locus_tag="KR231_001275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004631111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBH0003675.1"
                     /translation="MKNRLEEIRKERGIKQEELASILQVSRQTIGSLENGRYNPSIIL
                     AFKIARYFDMSIEEIFIYEEE"
     gene            complement(49842..50708)
                     /locus_tag="KR231_001276"
     CDS             complement(49842..50708)
                     /locus_tag="KR231_001276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HBH0003676.1"
                     /translation="MEWINKLNQAITYIEENLESGVDYAEAAKIACCSTFHFQRMFSY
                     IAEVPLSEYIRRRRMTKAAFELQNSNIKILELSEKYGYDSPTSFNRAFQNIHNISPSA
                     SRAKGVVLKAYPKMTLSIYVKGNIEMQYRIVEKKGFRIVGIKESMNMIVEECFEKVPK
                     LWAKCIKNGTIDKLSELINNEPCGLLGVSVCTNSKGLDYYIAAPTDKPVLEDTHEYLI
                     PSGTWAVFECVSPMPNALAIQELQKRIITEWLPSSGYVYANLPDIELYPNGDINAPDY
                     TTEVWIPIQKPS"
     gene            complement(50934..51803)
                     /locus_tag="KR231_001277"
     CDS             complement(50934..51803)
                     /locus_tag="KR231_001277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HBH0003677.1"
                     /translation="MDYKTIILNRKSVREYKNTDIKEEYLSEIKKYSESCKKLVPEID
                     VDVRIMNRSEVFNNLDKVAGYKGNMIDSPSYIIILSDIKDNYIENSGYIGESIIFKVT
                     ELGIGSCWVTFEDGKKVKEKLGINSDKEVTGIIAIGYGENVSNAKVLNATKTGQNYSK
                     SDMQVVTDKGSTRLGVEDVVYMNEWGNVASIEILEERALLDAFHYARLAPSTLNRQPW
                     RFIVDGGTVVLAVRKDGHTNLYEEKIDIGIVMLYFATIISATMFDLKWNLGTPDKDYK
                     VPEDYKIVGYCNI"
     gene            complement(52309..52530)
                     /locus_tag="KR231_001278"
     CDS             complement(52309..52530)
                     /locus_tag="KR231_001278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0003678.1"
                     /translation="MNVNNHKCPECGEHSKKFEIVEENEDCVIFECYTCGTISILKYC
                     ENCKEFVFVNIPNNVETYEYCCGKCNNKI"
     gene            complement(53032..54012)
                     /locus_tag="KR231_001279"
     CDS             complement(53032..54012)
                     /locus_tag="KR231_001279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0003679.1"
                     /translation="MGDTSRFYESVKNKYPKLKDGTRVHLWPKENIIIGPIYDEEDGY
                     KKSIGNVDSLSWKQIVILAECDGKNTTDDIINILSNRYRNIHNMKEKVMEFFMFYENV
                     YLTFEDDIQTLSSVFEITGNKSYITPLYFTIEIDGDNNTNDYFSEITSLLNCMYEKGC
                     RFIEVIGEDILKNKSMREIFQYMLDHFDLIVVTKDSFTIDRSLIKELDNYRHKVIWKV
                     YSKNDDTRIKLKEDIKITSLIKRGHTVVRGDREKAIKIEDMRFKDTKERFSKYGAEWS
                     HLYISSDGSVKSYSFQKDKRIYLGNIFNNSVEEIFLEMQNKIDKLEIVYQ"
     gene            complement(54176..54973)
                     /locus_tag="KR231_001280"
     CDS             complement(54176..54973)
                     /locus_tag="KR231_001280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018591576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HBH0003680.1"
                     /translation="METTEYTIFNKKIPKEFDNFKIVQVSDLHNKVFDKNNKVLIDKI
                     ESLNPDVIFITGDLVDGENKNFQVALDLIDNLVEKYEVYHIIGNHEQKSLIKKYKHLY
                     KDYFKELYSKKIINMENESVRIYRGNSHLNLYGLIIPLECYPYLFANNKKLELSDNFV
                     EDNLGKVNENEYNILLAHTPFFFEKYAKWGADLVLAGHVHGGIIRIPFVGGVLSPNRE
                     FFPKYDWGKYEKDNSTMILNKGLGGSKVLIRLNCKPEIVKITFKYEK"
BASE COUNT        17258 a        10146 c         5937 g        21656 t
ORIGIN      
        1 aataacattt aaccagtttt ttatgtaggt aacatttcta catttttata aattttttta
       61 cgttttttaa ttttataatt aaaaatttaa attttataca tattataata aattgtgata
      121 tatataaaat aattaaagat aaaaggagta ttttatgaac atacttggat taatagttga
      181 atataaccca tttcataatg gacacatata tcatttatct aaatctatag aaaaaacaaa
      241 tgcaacacat actgtagcaa taatgagtgg aaattttcta caaagaggcg aaccagcttt
      301 atttgataaa tacactagag caaaaattgc tgtcgaaaat ggtgtagact tagttataga
      361 attaccaact ttatttgctt gtcaaagtgc tgaaattttt tctcatggtg ctataacaat
      421 tttaaattca ctaaactgca taaattctat atgttttggt agtgaagaag gaaatacaga
      481 aattctttat aatatagctg aaattttagc aaatgaacca aatgaattta agttactttt
      541 aaaaaaatat ttagatgatg gtctgttatt tccaacagct agagctaatg cactttttga
      601 ttatatacat caagacaaaa aaaataattt tatacaaaat tattcaaagg aacaattatc
      661 aaaaacatta aattcatcaa acaacatact gggtatagaa tacataaaaa acctcatcca
      721 tttaaacagt agtataaaac catttactat ctccagggtc caatcagagt ataattccga
      781 agaaattgag agtgatattt gttctgctac tgctataaga acttcactta aagaaaatac
      841 agaccttttt catttaaaaa atgttattcc agaaaaaact tataacatcc taaatgaaaa
      901 aatagataat ggttttttac ctatgtttga tgacttcttc tttgatattt taaaaacaat
      961 tatacttaga gatatggaca ctttaaaaga gtattttgaa gtaaatgaag gcatagaaaa
     1021 cagaatctat aaagatatct ttacatctga atttctacat gaactacaat tagcaattaa
     1081 atccaagcga tacactttaa ccaaaatcaa acgaactcta aacaatatat tgttaggtat
     1141 taaaaaaagc gacatgcaac ttataaaaaa catagatact ataccttata taagaatact
     1201 tgcttttaat gataaaggta gagaaattct aaaagagata aaaaataaat ctgaaataaa
     1261 aataataaac aagttttcaa atatatcatt ttcattagat gatacgattt ttaaaacact
     1321 cataagttat gatataaaag ctacaaatat atataattca atatattata aaaacaataa
     1381 agatttagta aaaggcccta tggattttta tactcatcca atatatgtaa agtagttttt
     1441 taaaataact atatttataa aaatcatttt attaactctt tattatataa gatacaatag
     1501 tcttacttta tttatgtaca catgctttta ggatgacaac atcaacttaa atattatgtt
     1561 actttctaaa tttaagtaaa tattgccatc ctaaaaattt tacaatttag cttcagattt
     1621 aaaagtaaag tttaaaatat tatatttaaa tctaatttaa tattttttgt tttgtaaata
     1681 ttattaaatt aatatttcta atatattttc cctggattta aaatattttt agggtcaaaa
     1741 gctaacttta tatttttaat taacatcata taagcatctg aatttgattc atgtaagtac
     1801 tcttttttag catatcctat gccatgttca ccagaaactt gaccactaag ttctctagat
     1861 tttttataca tatagtcaaa agtttctttt aatcttattt tccatgtatt atcatccata
     1921 ccatctttta aaatatatat gtgtagattt ccatctcctg catgaccaaa actttttatt
     1981 cttattttta atttgtcttg aagctcgtga gtgtatctta taaactctgc tatcttatct
     2041 cttggaacaa cgacatcaca ttcatccatt tgtgtcgtag atgcctttat agcttctaaa
     2101 aatgcacctc tggctgacca tatagaatcg tttctttctt gtgtatctga tataaataca
     2161 tctaatgcac cattttctaa acataaatta gctacttttt catattcttt ttctatatct
     2221 tcagtgctat ttccatcaaa tgtaagcaaa agataagcat ctgatgtatt atctggaaac
     2281 tttttaccta aaaattcttc tgctgccaat atcacatctc tttccataaa ttctatagcc
     2341 gttggtattg attttgattt tattatttta ggaacagttt ctattgccat tgataaatct
     2401 ggaaatggta taagcaaact tatacttttc tttggtaaag gaagcaattt taatatagct
     2461 ttagtaacta ttcctaaagt accttctgag cccactaata aatcctttat actatatcca
     2521 gaactatttt taaccacctt tccacctaca tttataattt ctccatttgg tagtacaact
     2581 tcaagacctc ttacataatc ccttgtaacg ccatatttta ctgctctcat accacctgca
     2641 ttagtgttta tattacctgc aattgtagca cttttttcac ctgggtcagg tgggtaaaat
     2701 aaatctctat cttgaacata ttgacctatt gtcatcaata aaacacctgg ttctactgtc
     2761 aatgttaaat tttcataatc aacttcaagt attttattca ttttacatag attaatcatt
     2821 attccaccat ttatggcaac agcagcacct acaagaccag taccttgacc tcttggtgtg
     2881 actggtatat tatttttata tgcgtatttc attattttag atacttattc agtttcaagt
     2941 acatttacta aaacttcagg gtacttctca atccctccaa gttcatcatg tgaaaaatct
     3001 tcatttatat cacttccaac taatacattt tcttctccac aagtatctat taaaaaatct
     3061 atatcttttt tatcgattaa tttatacatt tctatccccc tatttagctg ctgatgccat
     3121 atatttttga ttattatctt tgttattttc tattttttca atcaatttag gaataatatc
     3181 ataaatatca cctattaaag ctaaatgtgc tacatcaagt ataggcgctt tatcatcttt
     3241 atttattgct actatatagt cagcaccctg catccctgca acaaattgaa cagctccaga
     3301 tacaccacaa gttattatca atttaggttt tacagttcta ccactaagac ctatttgttt
     3361 tttagcatct atccaacctg cttctattac aggtcttgtt cctgccactt gagcgtttaa
     3421 cttatcagct aatttatata tcatctccat atcttcttgt ttttttattg ctctacttgc
     3481 cacaactatc acttcagctt cttccagacc aacttcttta tttttttctt ttacactcag
     3541 taccttaatt ttagatttta gttctttttt ttctacttta cataaagtta tctttcctgt
     3601 agtattctct attttttctg gtgctgaaaa tattttatat cttacagtgg caaattgtgg
     3661 tctattatta ggtgtgttta tatgagccat tatatttcca ccaaatgctg gtcttatttg
     3721 gtctaaatca gtatttgatt gaatatcaag tattgtacaa tctgctgtaa gacctgttct
     3781 aaatctagcg gcaagtcttg gagctaatga cctacctaat gtagttccac caactaatac
     3841 tatcgttggt tttattttat ctataaagtt ttctattgct tttgaatatg gttctatcct
     3901 aaaatcttta aattcatctt catcatatac aaatacttca tccaccccat aagaaatcaa
     3961 attactgcac ttatctttta tgtcttttcc tacaaataca caatacacag gttgttttat
     4021 ttttgatgcc atctcacgag ctttacctat aagctcgtac gttacaggat gtatatttcc
     4081 attatgatgt tcaacatata ctgcaattcc cctccattca tctttattaa tttgtacttt
     4141 actactctct ataaattcaa atgcgccttt tggtccactt ttgacacaca acttgcacat
     4201 cttacagcca gcacttattt ctactatacc tgacttttct tctatagccc caaaaggaca
     4261 tatttctaaa attctcttta agtcagttat tttatcttga tttacaacta tctttgacat
     4321 ttattactcc cccttacacc aactttaatt cctctaattt atttacaagt gcaaaactta
     4381 gttcatctgc atttcctctt acaatatttt tatctgtatt tggctttgga ggaaatattc
     4441 ttacaacttg agtaggagaa ccattaagtc catagttatt ttcattttta tcttcaaagt
     4501 catctaagct atatacaggt atttctctat ctttagtatt aagttttaat ttaaatgaag
     4561 gtagtcttgg ttgaaaaatg tctttttcta cagttattaa acatggatat tcaatctcac
     4621 atacttgtaa atcatttggc atatctattt caacaactat actttcatct ttaacttcaa
     4681 ttaattttgt aacgttagta acatgaggta tatctaaaaa ttcagctact tcaggtccca
     4741 cctgtgctgt atcaccatca gtagtttgtt ttccacaaat tattaggtct acctttccca
     4801 tcttcttaat accttgtgat atggtatagg aagtagccaa tacatctgct cctccaaatc
     4861 tcctatcact tattaatgct ccttcatcag ctcccatcat aaaactttct tcaattacct
     4921 tctttgcctg aggaggaccc atgctaagta cttttagatt cgctttctta tcttccttta
     4981 ttctaagagc tgtttctaaa gcatataggt catagggatt catttttgaa tctactccat
     5041 ctctttttag tactcctgta gtttcatcaa cttctactga agtcgttcca ggaacttgtt
     5101 taatacatgt caaaatttcc ataaagtaca ctcctttttt atttaactat aactgatact
     5161 ccatcaggta taactactac tttgctctcc ttaccaacta tactattcgc catttctaaa
     5221 gcttctttaa agttaaatgc atgtttcata tgcatttttt ttatcatttc aggattacac
     5281 ttatctgtta ccattatcac agtatattta gataatattc tcgctagtat ctgaaattcc
     5341 cattggtctg gaatcgtatc tactctatcg acacttctaa ttttatctaa aagttgtttt
     5401 ggagaatctg catttgctac attttcataa aaagattgac ctccatgacc atcattacat
     5461 gctgaaatca ttattattac tccaccgtct ttacaagtag cttcagctgc tgtcattcct
     5521 ttaacagatt gataaatatt ttggtctagt ggatatccac catttgtagt tacaacaata
     5581 tcagatttta tagaatttac ttttgataac tctgttacaa atctacatcc tttagtatgt
     5641 gctttttcga catcaccagc aaaggaagca attatttttt tatctttatc tattacaaca
     5701 ttcaatatga atgctaattt tgcaacttta gctgcatata ccatatcctc atgaatagga
     5761 ttattattca attttccagt tcttgaatta tcactatcta taaagtcact acagtgattg
     5821 tacattatag tctttgcaga tgcgattcct ggaagtacgc tttttctgcc acctgaaaaa
     5881 cctgcaaaga aatgaggttc tataaaacct tctgctatca aaagttctgc ctcatatgct
     5941 agtttgttta tatataaatc tccacctgaa ggcaatatcc ctactttaca catagattta
     6001 tcatcagtag atatatgcat aactatatct tcattatcta ctatttcttc tcccatttta
     6061 taaattagct cttcccttgt acttggccta tgaaatccag ttgccactat aatcttcaca
     6121 tcaatttctg gattaacatt cctaatcctt cttaatataa ttggcatagt tattctactt
     6181 ggtacaggtc ttgtatggtc acttgtaatt atgactacat tctttttccc cttaaccagt
     6241 tcttccagag aattagagcc tataggatta ttcatagatt cttcaactat ctcttcttga
     6301 gtcttatgtt ctatataatt atccgatttt gactccaaaa caccgagaaa acgttcatca
     6361 ggtatttcta aaatcattcc ttgttttgaa tacggtactt ttaactttac catttttaat
     6421 ctcccattat aataaactat aaaattggta tgtggtcata ccagttttac atttatataa
     6481 tagtaccatt atctaccatt tgcaagaata atttatttta taacaaactt ttaattttca
     6541 ttttttctat aatttttact tataaaatcc atatgttcct ttgctttctc acatgcaagt
     6601 tctacatcat tttctacaac tgcattgtat atagcttcat gctgtttaag caatatattt
     6661 tcattaaaag gttctgcgat tattttttct cttgcatctt ctataaatcc atcaaataat
     6721 tttgatgctg tcataaaaag actttgaatt aaataatttt tacttaatgt tgctagttta
     6781 ctgtgaaatt tttggtctaa taataccagt actcgattat tatctttttt attagtttct
     6841 accctcattt catctattat atgtttcaat tctataactt cagaagaagt tattctcttt
     6901 gaagcaagtt ttgcaatctc aatttctagg attattctaa gctctaatat atcttcaagt
     6961 gtaccattat taagtttaaa aatcatagat aaaggttcta ttaaagtttt ttctatattt
     7021 gtacatataa aatttccttc accctgtctg ctttctatca ctcccatagt ctctaatacc
     7081 ctaatagctt cccttatgga agttctactc acattcattt gttcagacag ttctctttct
     7141 gatagtaatt tatccccctt ttttaactct ccatttagta ttttatattg tatttgctca
     7201 attacttgtt cataaacttt tttactagct atactattaa acattttttc ctccaatatg
     7261 ataatcgttg ttgtaatata tatctattat atatcttaag ccattacatt catatatttt
     7321 tattactttt aatataatat cttataactc aaatttacag gtgatattat gaaaaaaaat
     7381 aaaattattg ctttttttgc tccatctatc atagttggag ttctagtttt agggattatc
     7441 ctatacccaa atgaagctat aaaatctgca agagaaggct tttctatatg gtctaatgtt
     7501 ttagttccat cactactacc atttataatt ggagcaaact taattgttga tttaaaaata
     7561 gtggatatta tagggtttat catcaatccc ataactagat ttgtatttaa tgtttcagga
     7621 aagagcgctt tagcttttgc tatatctaca gtatctggtt atccagtagg agtaagttta
     7681 gcttctgaat ttaggagtaa tggacaaatt tctaagtatg aagcacaaag acttgtgtct
     7741 ttttgttcta catcaggacc tttattcata ataggttcgg ttggtacagg tatgttccaa
     7801 aattcaaact taggttattt aatgattctc tgccattatc taggaactat attggttggt
     7861 cttttcttta gaaattatgg taatgaaaac cttccaaaga caaaattgga tttaaaaaca
     7921 aatataaaaa atgtaatcaa cattagaaat tcaagtggga atggtttttt tgttttattt
     7981 ggaaatgctg tatttaatgg agtaaacaca ttacttacag ttggtggatt tgtaattgtt
     8041 ttttcagtag tatttaaaat actatctctt tttaatgtaa tctcattaat agcatcagtt
     8101 atatatttgc ctctttcatt tttaggtgtt agtaaagaac tctgtcaagc atttgtaagt
     8161 ggtctatttg aaattactat aggatgcaat aaagtatcta gtataacaag ttctccagaa
     8221 attttaagag catctttagc tagttttttg ataggattta gtggattatc catcctagct
     8281 caatgttgta catttctatc aaaaacggac atagatttaa aattatacat actaagtaaa
     8341 tttgcgcatg gagttttagc tgctatcttt atatttatac tttatccaat tgcaaactct
     8401 gctgtgttgg tttctagctt tgctgataca tacaacgtta tatataataa tttaatctgg
     8461 ttttattacc ttagctatta tgatacaatt cttcaaattg tagtaataat ttatctaatc
     8521 tcagccgtat ttattgcaaa aaaacatatg aaaactttat ctacaaatgg gaaactaatg
     8581 cgatataaaa atactttttt cactaagaaa ttttcacgaa aaaaataaaa ctaaaaataa
     8641 aactaataaa acttaactaa atacttccat ttttttatta tatttgtcat aattttaata
     8701 acctttttaa ttagtttaac agcatagtta tttcatcaca atttaataat tttattagaa
     8761 atatttttca aaaaattctc cttaatcaca tatatcacac ttgtataagt ttactgggaa
     8821 atttttccat tatataatat ttcatttata ttatataata aataccgacc taaacttacc
     8881 aaatcaaact aagaggagtg gttgaaaatg gcaacaagac ctatagaaat agacgaatat
     8941 aaaaagataa tggaactatt acatactggc tttacttata gtgaaaatgg cgttgaaaaa
     9001 agatttagaa aaaatcctaa agttgcattg gcactaatgt tagaagctaa tttaggtcta
     9061 agaatatcag atattttaag attaaagata ggtaatttta aaggtaatat gttggaaata
     9121 aatgaaaaaa agacgggcaa attacagtat agaccagtta ataaaaatat aattgagtcc
     9181 ataaatgaac atgcaagaaa gtataatctt aaatcaaatg actacttagt aaatataaag
     9241 acaaaggcta ttcaaaaaca gttgaggata atttgtaaac acttaaatct gtataatata
     9301 agtacacata gctttagaaa gctctatgct actactcaat ttgaaaagag taacaataat
     9361 ttagagttgg ttaaagaact tttaaatcac agctctgtag ccactacaca gcgatatata
     9421 agggtaactc agcaagctat taatgaagct agtgaaaatt tctttattgg ttaattataa
     9481 cgtatacatt tttctattat cttattaatt caccagatat taaaaaagag tgtctcaaaa
     9541 tgaacttttt agttcataag acactctttt tttataaaat caaatatatt tttattattt
     9601 caacactgga aaaaaggctt atctctctat tttgagacac cctattaaat tttcataatt
     9661 cttgcataaa catattaatc tatcttcaat aattttttag ctgattcact gtaattattt
     9721 ctttttacaa tttccaaaac tctatcaatc tcatgttctg actttgcact tacaaaaatc
     9781 gccaattctt catcatctat aatatcataa ctatctacat atttatctaa acattctaaa
     9841 attccatctt tattattata cccaccaaat ctaactactg cactacactc atcttctata
     9901 agtccactta aatccaattt cccttttgaa aaagacttta tatttgaact tctattatct
     9961 attatatcta taatatctgc ataaacagca cttcctgttg cacctcttcc agctccctta
    10021 cctacaaaag aaagttcacc tactgaatca cctactaaaa taactacgtt gaactcatta
    10081 tctatctttg aaagcatatt attattgtcc actaatgctg gtctaacaaa tccacttact
    10141 tctcctgatt catacttact tctagcaacc aattttatct tacaatttaa tttttttgca
    10201 tattctatat ctttttcatc tattgaagtt attccttcta ataataaatc tttccaatat
    10261 actatttttc cataagataa agtagacaat atagataact ttctagcact atcatatcct
    10321 aaaacatctg catctggatt aacttctgca aatcccaact cttgtgcctg ttttaaagcg
    10381 acatcatacg gtaaattttc atcatacatc tttgataata taaaattaca agtcccattt
    10441 aaaatagcgt ttatgctctt tatattgttg ccttccagtg attctatcaa tggttttaaa
    10501 actggaatac cacctgccac agatgcttca aacttgatgc taacattatt taagttagct
    10561 aattctataa ggtcactacc tttttcagcc agtaaatctt tattagttgt cactacatgt
    10621 atttttttat ttaacgctct tgttacataa tcaaaagctg gatttaatcc tccaattact
    10681 tcaactagta tatcaatatc cttgtcaaat atatcttcta tatcagtagt tatcttatca
    10741 aagtacttct tatacttgtg tttttcttta tttttaacta aaattccaac aacttctata
    10801 tctctttttg aagtattatt ttctattaaa tcaattaatc cacttcctac tgttccatac
    10861 cctaatattg ctatcttcac tgtaacatac ccccatcatt ttgattatat taaattattt
    10921 atatatataa atataccaat aaaaaaagct tgagtataaa ctcaagccat atgacgggtt
    10981 tatactcatc tttcagcata aatgctgcag gatttagcac caatgtataa ttaaatatac
    11041 tggttgccgg gcttcacagg gccagtccct ctgccactct tgataagatt gctaatttaa
    11101 atttatgttt aatagtataa tacaatttct tccaattgtc actatttttt taacttattt
    11161 ccctaaaagg atataaacta ttatctaaca gctcttttag ttggtttacc cttttttgta
    11221 acattattat ttttagtctt tgctttcgcc tgttcatgtc ctggaaaaag tattttaggc
    11281 tcttcaatat tcctcttgta aatagtaaat ttaaaaccaa tagcctgcac aaattcagct
    11341 cttaaagctt cacatactgc attagcagtt tctttagtat caagacctgc attttctaat
    11401 atagtaactt ttactaattc tctagttctt aacataccat ctaattgctc taagaaactc
    11461 tctgtaacac cttctttacc aatttgtgta gtaggcttta aagtatttgc caaagatctt
    11521 aaatacgccc tttgttttcc ttttaacata ttctcacctc tataattcta tacttaaatt
    11581 atctataatc tatatttaaa ttaattgtaa aactcaaatt ctaattcata aattttaacc
    11641 acatctccat cttctattcc catttctcta agcctatcaa aaacaccttg actctccata
    11701 gctttttgga aatattgaag ggattccata tcatcaaaat ttacagaata cattattctt
    11761 ctaagtgctt tacctgtaac tacatacaca ccatcttcaa tatctatact taactcttct
    11821 tcagtaccaa tatcaagttc tggtctatac atttcttctt ctgaaactag ctccacatct
    11881 tctacttctt ttagcatttt agaaacatag gctattactt catctatgcc ttgacgagtt
    11941 gctgctgaca ttttaaatac tgtatatcct ctgccttcta attcactctt aaacttctca
    12001 aacttactct catcttctaa tatatcaaat ttatttgcaa ctacaacttg tggtctcttt
    12061 gaaagctttt cattgtacaa tttaagctca tcatttatct tgtcaaaatc ttcaataggg
    12121 tctcttccct ctaatccaga tatatctaca atatgtatca atacctttgt tctctcaaca
    12181 tgtcttaaga actcatgacc taatcctatg ccttcagaag caccctctat aattccaggt
    12241 atatctgcaa gtacaaaact atctccaaac ttagtttgaa caacacctag atttggtgta
    12301 agtgttgtaa aatgatagtt tgcaattttg ggtttagctt tagttacaac tgatagaaat
    12361 gttgatttac ctacatttgg aaatcctaaa agaccaacat ctgctatcat tttaagttca
    12421 agagttatcc atctttcttc tccatctgta ccagattttg caaaagctgg agcttgtctt
    12481 actgcatttg caaagtgttg gttaccttta ccacctatac caccttttgc aactatagct
    12541 gtatctcctt ctttttttaa atctgctaat acaagacctg tagcctcatc tcttattact
    12601 gtacctgctg gtacttttaa tactaaattt tctccatttt taccagctct ttttcctttg
    12661 cttccgtcgc caccattttg agcttgatat tttttctggt acttaaagtc cattagagtt
    12721 ctaagcccca aatcaacttc aaatatgatg cttgctccac gaccaccatc tccaccgtct
    12781 ggaccaccag ctggaacgta tttttctctt ctaaatgcta ccgaaccatt tccaccattt
    12841 ccagccttaa caaatattct tgccttatct ataaacaaat tcttcaccta cttaattaaa
    12901 aacttttaat tagcattacc aaaaatacca ttataaattc atcagtatta taagaaaaag
    12961 gagtgcctca acactccttt tatgtatatt actcagctat agctactgga tatatactaa
    13021 ctttttttct cttcttgtct tttctttcga atttaacagt accatcaact aatgcaaata
    13081 aagtatcatc actacctttt ccaacattag ttcctggatg tattttagtt cctctttgtc
    13141 taactattat acttccagca gttactaatt gaccatcgaa tctcttaaca cctaatcttt
    13201 tagatataga atctctacca tttttagaag aacctacccc ttttttagat gctaataatt
    13261 gtaaattcat gtttaacata tggagtcacc ccctactttt ttaaaatttt tatatttttt
    13321 gggtattccc gtttaatttc tttaaccgct aattgaaagt gatttagtaa taattgtgcg
    13381 tcttttacat gtgtatcttt gactatacac tctatatgac cttcttctcc tactactttt
    13441 tcaaattcaa tcttttgtaa tttgtctaaa gaatttataa ctgcaatagc attagatgta
    13501 actgcagcac atactatatc atagcctatt tcagcaaaat cagcatgtcc ctttaaacaa
    13561 aaaccttgca acaagaaatc atcattataa taatatttaa cttttatcat aacttaacca
    13621 ataactaagc gtttattttt tctacaacta tcttagtgta tgattgacga tgtccttgtt
    13681 ttcttctgta atcttttttt gctttatact tgaaaactat aactttctta gctttacctt
    13741 gttcaacaac tttagcttga acagatgctc cttctactac tggagaacct aattttaatt
    13801 ctccatcttt agagcaagct aatacttcgt ttaaagtaac aacatcacct gcgttagctt
    13861 ctaatttttc aacgaataat acatcacctt cagaaacttt atattgcttt ccaccagtct
    13921 ttactatagc gtacattaaa tacacctcct cggcctcaaa ctcgccagta caaggtactt
    13981 catttgaaga tttaaacctt tactgtgcgg cattacaatt attaattata aaatatttac
    14041 attttattgt caactatttt atcgaaaata acattggttt tattgtgctt taatgtacta
    14101 tttgcgttta aagaaatctt tatattatat ttttcaccaa ttttatcaat tatatccata
    14161 taatattctt ttatttgttc aaaaataaaa tcattaaatt ctaccattat gtttttgtaa
    14221 acagtatgtt cacttattct cataatttct ttttcaatac tatctagtat ataatgtaca
    14281 gattttattg tttgttcacc atcacaacat ggacaagaca ttaaataata cttatcaatg
    14341 gattcttttt ctctacgcct agcaacttct actaaaccaa gttttgtcat acctaatact
    14401 tcagcttttc ttttatcttt attaaattct tcttctagga tgtgtaaaat ctccttttga
    14461 tgcttctttt tatgcatatc aataaaatcg attattatta tcccagctat gtctctaatt
    14521 ctaagctgtc ttacaatttc ttttgcagct tcaagattag ttttataaac ggtttcatca
    14581 agtttaccag ttccaataaa cttacccgta tttacatcta taaccgtaag agcttctgtt
    14641 ttttcaatta ttaaataacc tccactcttt aaccatactt ttttatttaa taatttttct
    14701 attttagatt ctattctgta taaatcaaat acatctctat tttcctcaag acacagttta
    14761 tcaacataag tcttatctat acctcttaaa atagacttaa gttcagagta cttatcataa
    14821 ctattggtaa ttatagattc aatatcatca ttcacattat cttttacata tttagttgca
    14881 aaatctaaag acttatataa taatttcgga cctataccaa gtttatattc ttttaaaatg
    14941 ttttcatact ttaatttcaa ctcttctata tctttcttta tttcatcatg agtgcaacct
    15001 tgagcctcag tccttattat taatcctaga ttttccttat ttactgcctt agtaattttt
    15061 tttaatctaa atcgttcttt ttcatcagta attttatttg atattgtagt tctatcattg
    15121 gaaggtatat agacaatata ccttccagaa atactaatct cagtgtttaa ttttgcgcct
    15181 ttagttccta tttcttcttt atttatctga accaaaatat cctgaccaga ttttatagta
    15241 cttccctttt ttaattgtaa ataagcaagt ttcttaaatc caatatctac aaaacaagct
    15301 tctattcctg gtataacttt ttttacgatt ccacgatata tattggatac agtcttctta
    15361 tttaaattgt cttcaacaaa aagttctgtt aatctttcat cttcaagtac tgctgttttc
    15421 tgggacccta ttagggactc aataactatc tttttcacaa cttcacctct cgagcttaca
    15481 taggagtcac taattcccca tcttctaata catataaatc tcttctcaat atatcaacat
    15541 ctaatgggtc aatatcaagt tcaaacatct ctaatatctt tggtataagt atattagtat
    15601 ttaaattagt ttttgagcct gtagctatag tagcagtaag agtaatatgt tcatcttcta
    15661 aatttaaaac atcaaaggtt cttatcatag gtcttatatc tacttcaacc atcttacctt
    15721 ttttattctt ttttgttatg attatttctt tattattcat aaagtcaatt acttttcttt
    15781 ttacaaactc tttcgtcata ggtcttttca aatctatatt aaacaaatat tctccatagt
    15841 ctatcacaga agaaagagaa ggtgtttgtc tatcaatttc ttttgctttg ataaaatcta
    15901 tcccatctgg aagttgaatt gatactttat ttaaaaattc ctctactgat aaatcatctt
    15961 cttctatttc aatatctaca tactcacctt gactttctgt ccctaaagcc aaagcattgc
    16021 cataactcat tttagggtga ggattaaatc cttgagaatg tgataagttt atttcagctc
    16081 ttctaaacgc tctttgtaac aatctctgaa ggtcaagatg tgatatatat atcatgtcgc
    16141 cttccttttt aaattttact cttattatct tactcatatt agcaaagccc ccttcctata
    16201 tcatgtatat ttattccaca accattgcag ttatgtctac aatcagaagt gattttttct
    16261 tttttagcat tttcgtcttc tctaattaag aattttttac taatacctac atctatatgg
    16321 tcccaaggaa atacctcttc atagtttcta tttctatgtg cataaaaatc tatagaaaga
    16381 ttattctttt ccatagcttc tttccatata tctaaattaa aatgttctgc ccatccatca
    16441 aatttagcac ctagtctaaa tgcatcatat ataacttttc ctattcttct atcgcctcta
    16501 gctactactg cttccatcaa actagtcttt gaatcatgat aattgtattt tatattgtta
    16561 tttcttaatt tatttactaa atgtctctgc ttattaataa cttcttctgt agtatcttga
    16621 ccatgccatt ggaaaggtgt aaatggcttt ggtacaaatg tagaagtact cactgtaaca
    16681 ctaaaacttc tctttagctt tcctccattt acttttctat aaatatcaat aactttataa
    16741 gctaatttag ctataccatc taaatcttca taagtctcag ttggtaaacc aatcataaaa
    16801 tacaacttaa cactattcca ccccatctca aaagctcttt ctgttgcatt ttccaaatct
    16861 tcttctgtaa cacctttatt tataacatct ctaagtcttt gagttcctgc ttctggagca
    16921 aaagtaagtc cagattttct tacttgttgt attttatcag caatttccat tgaaaaatta
    16981 tctaatctaa gggatggaag cgaaatccca atattattag atgcatattc atctaccaaa
    17041 taatcagtca actctgataa cttactataa tcactcgtac taagtgatga taatgatatt
    17101 tcatcatatc cagtattctt aactaattta tctaatattt ctttaagtct tttaacactc
    17161 ttttctctta ttggtctgta tatcatacct gcttgacaga atctacatcc tctagtacat
    17221 cctctaaata attctagtac tattctatca tgaacagtat ctatataagg tactattagt
    17281 ttttctggat aatctacagt ctcaacatct tttattatcc ttttagtagg atttttagta
    17341 atcccttctc tattaggagt tacactttga actgtaccat cttcattgta cttgacatca
    17401 taaaaacttg gtatgtatac tccttctatg ctagatattt tatataaaaa atcttctcta
    17461 gtcgttttat ttttcttcca ttctttatac tcatttacta cttctaaatt aacctcttca
    17521 ccttcaccta atattactac atctacaaaa tctgctaatg gttcggaatt ataagcacaa
    17581 ggaccaccaa ccattataaa tgggtcttcc aaagttcttt cttcttttaa tattggtata
    17641 ttggctaaat ctaatatatt taagatatta gtgtatgaaa gttcatattg aagtgtaaaa
    17701 gtgacaaaat caaagtttgt tataggctct cttgactcta atgcaaataa tggtatactt
    17761 ttttctctca ttatattttc catatcaact gcaggagaat acactctctc acaaaataca
    17821 tcttcatcct tatttattac atcatataat atatgactcc ctaagtgact cataccaact
    17881 tcatataaat ctggaaagca atgtgcatat cttatcaatt cactattact agtatcttta
    17941 tgaattgaat ttatttcatt tccaagatat ctagcaggct tttctacttt ttttaagatt
    18001 tttttcaagt ctactttatt catttattaa aattcctcca aacaagctct ttatttttat
    18061 tcttatttat aagtaatatt atacacgata aaatattttc tatcaaaaat ataactaaaa
    18121 tattgaattt aaaatacata ttattcacaa aatagaatag ctaaaaatat ttaagaatat
    18181 tttctattaa atttttattg aaatacaatt tttttacaaa gtatgatata ttataaacat
    18241 aaaactattg ttttacatga cttatcatga catcttttgt ttcattcacc tcaaaatggg
    18301 gtatgttact tatataatga taaattttag gagggttaaa aatgagtaaa gtttttgaag
    18361 taaaaaaaga tatctacttt actggagtag tagatgaagg tttaaaagta ttcgacataa
    18421 taatggaaac tgagtttggg acaacttaca actcttattt aatcaaggac gaaaaaacgg
    18481 ttttatttga cactgtaaag gcaaatttta aagatgagtt tttaagtaat ttatcagagg
    18541 ttactgatat agctaaaatt gactatgttg taattcatca cacagaacca gaccatgcag
    18601 gtagtttaaa atacttatta gatataaatc ctaatataga agtttattgt actaaagctg
    18661 ctaaactata cttagatggt caaataaata gaccttttaa ctgtcatgta ataaaagatg
    18721 gtgaaatttt aaatatcggt aaaagaaatc ttagatttat aactgctcca ttcttacatt
    18781 gggttgatac aatgtttact tacattgagg aggacaagac tcttttaact tgtgatgcat
    18841 ttggttgtca ctttgcaagt gttgatgcag aggtagtgaa tagtgaagat tatctaaaat
    18901 cagctaaaca ctactatgat tgtatagtta agccatttgc taaacatgtt ttaagtgctg
    18961 tagataaggt ggtaggacta aacatagaat ttgatactat attgacttct catggtccaa
    19021 tgcttactaa agacccaatg gctgctgtta aaagatatgt tgagtggtct acagaagctg
    19081 ttaatacaac taatcaaaat caagtttcta tattctactt atcagcttat agtaatactt
    19141 tagagatggc taaaaagata aaagaaggac ttgataaaga aggtgcaaag gctgaattat
    19201 atgatttaga agatatgaca ttaacagaaa tgcacgatac attagtagtg tcaaaagtaa
    19261 tattactagg ttctccaact ataaacaaaa ctatggttaa acctatgtgg gatttattct
    19321 ctgttataga cccaatggct aaccaaggca agatagcagg agtatttggt tcatttggtt
    19381 ggagtggtga aggtataact atggctgaga ctttacttaa atctatgtca ttcaaaatgc
    19441 ctgtagaatc tcttaagaaa aaattcttcc ctagtgaaga gacattaaaa gagtgtatgg
    19501 catttggtgc agaatttgca aaattagtta aatagccatt aatcaaacat aatattattt
    19561 aaaataaatg attttatatt taaaaataaa ttaaaatgga gttgtctcaa aattaatttt
    19621 tctaatctaa ttttaagttc aactcctttt ttattttcta aaatgactga tataatgata
    19681 aatgcaccct ttgtgcgagg gtgcattatt tataatatgt tctatttgta cactagtata
    19741 tttgtattaa ttcacatatc tagcgtatgc taccatccct cttccagaat tagatgccgt
    19801 ttcaccaatt tccactttaa taattacatt attttcttta cacttttttg ataattctgc
    19861 tgcagaaagg ttcttaccag taaaatctaa agaaaatggc ttatcatatt caaaaggata
    19921 ctcatcaggt acaccatctg gagctaatgc aaccatacca tatggtgtat tcataaaccc
    19981 tattacagta actgtatgct ttgatgggtc taaatttgaa tttttgcttg taaacttaat
    20041 tgtatttatt gatgagttga ttaaactaca cggaactccc tcatacattt caatttttgg
    20101 acgtagatta tttccataaa cttcatcaag tattgcccct tgttgatctg ctatcatagt
    20161 gtgattccca ggtccaactg gcgcagaagg cttagctggc gtaggtttct taacagttgg
    20221 cgttggattc tgtgtcttta ctacttcgcc aacagctgga tatgctttct tgtcaaatgg
    20281 taatgggtga gtaagactct tgtatatgat gtctgctcct gctgatttgt tggcatcaat
    20341 atctacatga tacaaacgtc catcctcaaa acgaataaga ttccactgat ggtcatttgt
    20401 tgtactatgt acataataac attcaattcc catagcatca cataaagctt tcaagctcct
    20461 acacattcca gaacaagcac cttttttagt aaccaatgta taagcagtat tggctccctc
    20521 tgctgcgttc cagttaacat atgttgtgtt gtttttaatg tgattataag caaccctaat
    20581 cttagcatct gtggtcatgt tctttgtaat tttcttgttc ataaagtctg ctgttgcttg
    20641 tgctaccgaa ttaagttgag cttgtgataa ctttggacca tatatactgt tggttccagc
    20701 tacataactt ttcggtgtct ttgcagtaac atctttagct gtcataccat aaactgttac
    20761 actcatacat gaggttaaaa ccatcattgc aatcaatagt ttagtagcta atttcctgat
    20821 ttttttcata ttagcattct cctttataat atattttact ttcaattccc taccattaat
    20881 taagttcatt ttagatttaa aatatggatt atcaacatgt atgcatagca attcacgtgg
    20941 tcatagaata tttagatttc ttggaaaatc tgttctatat ttcctatata gttcgtatac
    21001 aatccaactc acaaacctgc atttttgata tcatcacaat aaaatgataa taattaatat
    21061 attcaaaaat gttggtctgt aacaggtatg tcaattttcc aattattggt aatggcgaga
    21121 gtgaggagaa ttgtcaataa tacatttaaa attaaaattg tatacacttc atacattctc
    21181 ccctaacaac attatacaga ttataatttg tatattcaat acattttttg gaaagtataa
    21241 ttatatcaaa atatgtgatt atgtatagat acaatccact atggagaaat ataaaagaaa
    21301 agagtataac aaacaataaa aaataagatg attcaaattt tattttgaaa catcttattt
    21361 actctacaaa ttaagattat ttggtgaatt atttaattat tattttttat taaagaaatt
    21421 ttaaatctta atataaaata cgctattata cataataatc caaatgcaaa tgctactgga
    21481 attaacatct ccgattcaaa ataaaagaaa tattctaaga aaatatctgg atttactata
    21541 ttcccattct tgtctaaaaa atcttttcca ttatatccta aatgctgtat aaaattactt
    21601 atgttattat aatctgcttc cctctcatat accatattag cattcaatcc agaagaactt
    21661 aaattagtgt ttccatcttt catatctatt acatatagtc taagagcttt gactttacta
    21721 tacttatctt tatcaagtat tttttcaagt tctaacttat attcaccaat ctttgtcata
    21781 tcatgtcttt ctgccaattg ctttatttct ccatcaagtt cttttcctaa attatacata
    21841 ttatgttgta aactattatt gtaataccac ataaatccag aaattaaaaa tgcaattata
    21901 cttatgtaac ctaatacttt tttaaacccc attacaattg atttatgcct atccaatgat
    21961 aaagatagtt cttttattat attacataat tcatactgca tttcatcacc atcatcaaat
    22021 ctttcaattg cttttttaca tgcttcttct tcatctaatc cttctaattt aaattcattt
    22081 gcagattcta taagatggca tctcatttcc tgttttaatt ctatagtact tttattgtca
    22141 cattttttat atagtttatc taaatattca tctattagtt tcataaatta atccacctct
    22201 cccaaaaatt gattcataac ctttttaata aatctccatt cttgtttctt tatttctaaa
    22261 aaatctttac cttcattagt taaattataa tattttcttc ttccacctga actttgttca
    22321 ttgctataat aagatttaat taaattttta gattccattc ttttaagtgc aagatacatt
    22381 gttccttctt ttaattcaaa ctcacttctt tctcttactt gctttgcaat ttcatatcca
    22441 taacaatctt tcttttctaa tatagaaaca attaatatat cgatataacc ttttaacact
    22501 tctttattta actgcattat gtaccaccgc cttttcacct actactctat aatgtatagt
    22561 acttatattt actataatat tacatagtac tctatattgc aaggtttata ttctacaata
    22621 gacttaaaaa taataaatag ctgtatatta atatttaatc tataaatact aatatacagc
    22681 tatttatcaa attttaaaaa taaatttttg ttttattaat gttgtcataa caacatttac
    22741 ttggttgaaa tagtattacc tataagttta aatatatata ataatagact tgattctatt
    22801 tcatattatt aaaatagagt aatagtttaa attctactac tctatctata atctatttcc
    22861 taattattta atctcaaatt tagctcttca tcatttaaat ctttcataag atttctacag
    22921 gtactagatt tattccaaca gaaagactag ggcattaaac acttatatat ctgtttcttt
    22981 agactgtaat attaatattt tttaaatacg ttgacttttg ctttttctaa cttctctcca
    23041 tgatagttct cctctatcaa gagcttttat aaatatttct gctgaagcta gatttgtagc
    23101 tattggaaca tgataaacat cacaaagtct tattaacgct tgtatatctg tttcatgagc
    23161 ctgagatgtc aatgggtctc ttaaaaaaat aactaaatct atttcttgtg ttactattaa
    23221 agaacctatt tgttggtctc cacctaaagg accagatgct aatctattta tatttaattc
    23281 agtttcatcc attattcttt ttcctgtagt tccagttgca tatagtccat acttttttaa
    23341 aattgattca taacctatac aaaatccgac catagtgttt ttcatttggt catgtgctac
    23401 taatgctata ttcatatatc taatctcctc aatttatgtt tagatgtatt taaatttaga
    23461 aatttatttt ctttcttctc atacacacat ttagtactaa tcctaagttt gctaaagatg
    23521 tcaataacga acttcctcca taacttacaa aaggtaatgt tactccagtt actggtatta
    23581 acgcaaccgt catacctata ttttggatta tctggtaacc aaacattccc ataacaccaa
    23641 ccactatgag ggttccataa aaatcttttg catctcttgc aattgctaaa agccttaata
    23701 ggaatatcat aaataagatt atcaacactg ccattcctat tacaccaagt tcttcaccta
    23761 caacagcaaa tataaaatca ctatcttgta caggtaaaaa atcttcttga ttttgacttc
    23821 cattgtaaag tcctttacca gttacgcctc cagaaccaat tgcaatcaga gattgcataa
    23881 cttgatagtt tccttttaga gttacatctt ctggatttag aaaagcttct attcttacct
    23941 tttgatggtc tgccatcatt aaatacatca gtggcattga cactaatagt atgattattc
    24001 ctctttttat caactttgag ctaagacctg ctgtgaacag cattgcaaat atcatacaac
    24061 aaaatacaat tcctgttccc aagtctggtt gtgcaatcaa taatccgata aatggaagag
    24121 aataaactac aacaggcata acttccttta acgtatttaa tttatccttt ttggattcaa
    24181 gtatctttgc ataacttagt acaaatgtta atttgactat ttcagatgtc tgcaagtcaa
    24241 gtggtcctaa gttaatccac gacctagctc caccttttac tgtcccaatt ccaggtaata
    24301 aaactatggc taacaaaata agacttatta tataaagcgc tttataatac ctgcctagaa
    24361 ggttatagtc aaaaaataat atgactataa tcattcctat cccaagtaca aaagctaatc
    24421 cttgtttaat caattgatta tatgaacctg ttgaattagc atgtgttgca ctactaagta
    24481 taacaagccc aaaaataaag atagctaata ctgtaactat aagtttccag tctaactgtt
    24541 ttatcaactt aattgtcgac ttataattaa tattgatttt tttcaaagaa tcaccgtctt
    24601 tctatcttta aacatataat taaataaaag gggcatatac caataaggat atcccccttt
    24661 taagcactaa ttacatacat ctatctttta tattctttag tggtatatta gcaactaatg
    24721 cagatacagg tttgtcatca tgctcacctc tgcatttaga catttttatt tcaagaccat
    24781 catcttctat ttctgcataa ttagctatta cttttaaaat gtctgttttt atcatctcta
    24841 aaagttgtgg tgaacaatct actctatcat gaactaaaac tagctttaac ctctctttag
    24901 caacagattt actagtttta gcctcgttag aaaaaactct aaataaatct aacacagatg
    24961 tatcctcctt tgctacttag ccatgctaaa cattttttta agtctaccaa agaatccatc
    25021 ttcaacttca agatcaagta gaggaacttc ttcatttagt atcctttttg cgatattttt
    25081 gtatgcttga ccagcaagtg acttagaatc aagtatagct ggctctcctt tatttgttga
    25141 tataattatg ctttcatcat caggaacaag acctaacaaa tctattgcta atatttctat
    25201 tatatcttgt ttatccatca tgtctccacg cttaaccata tcatttctaa ttctatttat
    25261 aactaatctt atctctttta tttcatttgc ttctaataga cctattattc tatcagcatc
    25321 tcttactgct gatatttctg gattagtaac tacaatagct ctatctgccc cagctactgc
    25381 atttttaaag ccttgctcaa tacctgctgg acaatctatt attatatact cgaaagattc
    25441 ttttagtttc tcacacaggt caatcatctg ctcaactgag acagcatttt tatctctagt
    25501 ttgtgctgct ggtaataaat atagattatc aaatcttttg tcttttatta gagcttgctt
    25561 aagcctacaa gttccttcaa ctacatctac tatgtcataa actattcgat tttcaagacc
    25621 cattactaca tctaagtttc taagtccaat atctgcatcc acaactactg tttttttatt
    25681 ttctaggctt agcgcagttc ctaagtttgc tgcggtagta gtttttccaa ccccaccttt
    25741 accagatgtt ataactataa cttcgctcat aatactaccc cctatttttc tttctatttg
    25801 tctaactttg acaaatagct ttcgattaca attcttccat tacttacaaa ggctatttct
    25861 gggctaattt ctgattcact ttcataattt tcttcatcat ctggagcttc tgcaatatta
    25921 tctgctattt gtaatatttt aggattaaga tttccagcaa caacatatgc aaattcattg
    25981 ccttctgcac ctgcatgtac aaaaccttct attttaccca ttacaaaaac attacctcct
    26041 gctacaacct tagcaccagc atttatatct cccataacaa ctgtatttga ttttgaaagg
    26101 acttttgaac caggtttcat atcattcaat ataactacat caccttcaaa ttcaatattt
    26161 tcaccagatc ttagggtatt gacatatttt gttggaaaat tactattttc ttcaattttt
    26221 tgatcttcaa caaattccac atcaaatcta gaagtaattc cttctttaag ttctagaatc
    26281 tccatgtcag ttaaacaatc actattaatt ttactaattt tagccccatt aaaaaagcca
    26341 acatatgctt ccaatttgtt tattattttt tcctgtattt cctcaaatgg agcttctctt
    26401 tttatattta ctattatccc tcttttatta cccttgaact ctactagttc ttgactacaa
    26461 atttctctta aagacataac aacctccaga gtgatatatc atttatattc ttcaaatacg
    26521 ctttaaaccc ttttattttt tctatataaa gctaaagttt atacatagat tgagctatct
    26581 attaatttgt gactcgaaat ttatattttc gtcagaagaa ttgttaacat cattcgtctt
    26641 gttgtcattt ttactattag ttggctctaa tcccatataa gttccaataa cttctctagt
    26701 tggtaaaagt gagaatacac ttgaatcacc ttgaggaatt acacatacaa cagctatttc
    26761 tgggtcatct gctggagcaa aagcaacagt ccacgtaaaa gaaccataat cttgtttaaa
    26821 tctatctatt tggtcatctg ttatttttgg atttaattct tttatagctt ttcttagata
    26881 tgaagaattc accttatcag tgtcctctaa tctaactttt actccatctt ctaattcttc
    26941 ctctaatttc tttctttctt cgtctttcaa atctttattt tctaatttct tttttatttc
    27001 cttttcctta gctaatgaaa gctctttttc tttttctgct ttcatcttat cagctagttt
    27061 aatcgcatca tttaggttga cattataaga tgacatatga ctttttaaat attcatactc
    27121 gttatctgta ggtattttcc cacttttctc agctgtacca gtttttgctg ctacatctat
    27181 tggaaaatca gcaaaagcac tcttcgctgt accttgtctt gcaaccaatt tcataccttt
    27241 tgttaattct tttaagttat ctggattttt aaaaggtatt ttttcgactt tcttctggtc
    27301 attaatttta actgatgaat aatcacttga aacagctcta tcaactacag ataattctac
    27361 taaattacct ccatttgcta tagcagctac atatcttgat atttgagctg gtgtataagc
    27421 attttcacct tgtcctatag ctaagttgaa tgtatctgca gtactccatt ttgcaaaatt
    27481 aaaataacta aatactgcta aatctgctac ttcttcaatt ctatcttctt taacatccaa
    27541 tttttttagc ctattcattg tttcaactct accaggagtt ttcttttctg ctgcccagct
    27601 tacaatctca ttgattcttt tctcatattc tttaggattt ttttctctag ttatatcaac
    27661 aaaatcattt gccatttctc tttctaaatt tgactttaga agagcttgtg ttgatttcaa
    27721 tttatcttct gtgctaggaa ctttacctgc tctttcttct acttcatctt gaagccctgt
    27781 attttggtca agcccaaata attttgcata ctcaagtatt ttatttgcat tcatatctat
    27841 accaatgctt tttccatctg gccatgtttt acctgtacca attgttgcca tatatatatt
    27901 acaagactct tgtattgctt tatataagtt tgtcatacca tggtttcctc taccatggtt
    27961 ccatacatag tcaccaaaag attttttacc taacattata accccagggt catttatagt
    28021 aaagtttgga tccagaccat tttctaacgc tgccattgaa gttaccatct taaatgaaga
    28081 acctggctga aattcccctt gtgtaaccaa gtttaaaagt ggacttcctg ctagtaagtc
    28141 atttggattt tttggttgaa gtgctttata atcctctgta gaaatacctt ttgcaaattt
    28201 atttgggtca taattaggat aacttgatga agctaatact tctccatttt taacatcaat
    28261 agctataaga gctgctgact gtgcttttcc tgcatatgca ctaattggtt tgtccccaaa
    28321 tttactttta aaagtacctc ctttagaagc aacttcgatt atctgtttta atgcattatc
    28381 tgaaacttct tgtaaatctt tatctagtgt aagatacaca gtatctcctg atttaggttt
    28441 tttagattca atttctttac tgattctacc caatgcatca actttaacca ttttataacc
    28501 atcagttcct cttaatctac tttcattact cttttctact cctgcaagac ctaccatatc
    28561 tccagtttca taaccttttt gaaggtatga ttctatttga gtggatggca tttttcctac
    28621 atatcctaac atatgagaag ctaatgaccc attaggataa tatcttactg gttctactgc
    28681 tattgaaaca ccaacaaggt ccatagcact ttcttcaatt tgagcaatcg tagtttctcc
    28741 cacatcctta gcaatagtta ctggattata ttgagaatat ccttttgatt ttatcaaatc
    28801 ccttacgacc attatttttc ttgcatcttc atcactcaaa cttttatcaa tttctaatgc
    28861 atcactattt cttacttttt caaacgcttc tttggcactc agtttagttt cttttatctt
    28921 ataactagcc aaccaatctc tcttatctct ttctgctgtg aacatccatt tactaactaa
    28981 aataggtgga taatatccat tttcatttag ttttgcctgt aatcttgtcg catccaatct
    29041 tttatcttct tgagataata ttccagctga tataagtttg tccaccaagt aataaaaact
    29101 ttccttagca ttataatcat ttggaatacc attttctgat ttatattccc taatatctct
    29161 gtcatatgta taatagtact ttccattttc tacatatata ggaaactcat ctacatattc
    29221 ttcaccattt ctctccagca aatttataag ttttaatgat atttcatttg ctcttgaatg
    29281 cttatttgca tctttcttat taatatcgtt acctgaaact tgaacagtaa ataagttttt
    29341 atttcctgcc aacagtcttc catatctatc ttttatttct cctcttggag cttctattgc
    29401 caacttttta tatgttttat tctcagctaa ctcattgtaa tattcatatt taaatgtagt
    29461 catatagatt atttttacta aaatagctaa aaatatcacg cccatgacta tcttaattat
    29521 ttttagtcta tcaacttgtt tattttcttc catgaaatca ccaactaatc ttctttaagt
    29581 tttaaaactg ctcttttaga taagcgatat attactaaac caattaaact attcactatt
    29641 ggtgctacta gtagaccttt tacaaaaagt gttgatatgt tgtagctttg ataaattata
    29701 ctagatgtac ctatattgac aattgaatca attaaactgc ctataaaaat taaaacgaaa
    29761 gtaataatat aactaccttt atatagctga tctctcatgt atccaattgc atatgcaata
    29821 ataaacaaaa ttaatgcatt tacaccaaaa attccaccaa cggttatgtc tttaataagc
    29881 cctattattg ctgctataat cccaccttct aattcatcta aataaagaga gattatggtt
    29941 acatatataa gaactaaatt aaagcttatg ccaaaaatat ctatataatt tgttatacta
    30001 ttttctatag tcataagcac aatccccaac agacaaagta aaactttttt cattgttttt
    30061 atccccttta tcctatattt cttggttcta tgactacaac gtcatttata ttcttaaaat
    30121 caacataagg ttttacaact acatatttta atgacttatc tttatcatca accacttttt
    30181 caacttcgcc aattggtata ccatctggga agaatccaag acctgatgtt gttattatat
    30241 ctccttgaat tacattatat gatgagtcaa acatatatcc ttgcaaatat cctttactat
    30301 tataactatc tttattatct aaagtagtat tttgagtaat tgtaccttta gcattggcat
    30361 cctttgctag tttaaagctt acagatgcct tagaatccaa tagtgaaatt gccttactat
    30421 aattgttgga aacctcataa actatgccaa ctaatccact accattcata actatacttt
    30481 ctttttttac acctgaattt tttcctgcac ctatgacaaa actctcatac cagtttccat
    30541 catttttacc aacaacactt gctgaaatac ttgtcgcctt atactcttct tgtacaaagt
    30601 tcagtgtctt ttttaactct tctagcgatt ctgttttatc tagtttggca tttaaagcta
    30661 tcatattttt tttaagtttt tcattttctt cttctaattt ttttaccttt ttagaattat
    30721 ctttaaaatt tgctacatct ttaaaaccat ttttgataaa agaaaatcca tcatttattc
    30781 ccttacctac acttgtaata gcatctgaag ctactcctaa atttactgga ctaccactag
    30841 aaaatttacc aattgatata cccacaattc caattaaagt gatagcaact acgcccgttg
    30901 ctatcacttt aacattaatc ctttttttct catttttgtt cttgtcaaat ctcaaggcca
    30961 tcaccaactt ctaattctta gtattcatca ttaatacttt ttcaaagatt tcttggtctt
    31021 caacagattt acctgttcca agtgcaacac aatcaagagg tgtttctgct atttgtacag
    31081 acataccagt ttcctgtgta ataagcttat caagacctct aagcaaagcg cctcctcctg
    31141 ttagcattat tccgttttcc attatatctg aggctaattc tggtggagtt ctttctagtg
    31201 tagattttat tgcatctact attgaactta caggttcttt taatgcttct ctaacttctg
    31261 tagagcatat ttctattgtt ttaggtaatc ctgagattaa atctctacct cttatttgca
    31321 tatttatttc ttcatcatct ttaaatgtag aacctatgtt aatttttaca ttttcagcag
    31381 ttctttcacc tatcataaga ttatattctt tttttacata agccactata gactcgtcaa
    31441 attcgtctcc acctattctt atagatttag cagtaacgat tcctcctaaa gatattacag
    31501 ctatttctga agtacctcca ccaatatcaa ctaccatatt accttctggt tcttcaactt
    31561 ttaatccagc ccctatagcc gctgccattg gctcttctat aaggaatgca tctttagctc
    31621 ctgcttgtct tgcagcctct tctatagctc tcttttctac ttctgtaact ccaaaaggaa
    31681 cacatatagc tattcttgga cttacaacac cttttttatc agccgctttt tgtataaaat
    31741 agctaatcat tgattgagtt atgtcaaaat cagctattac tccatctttc ataggtctta
    31801 tagctactat atttcctggt gttctcccta tcattttttt ggcttcttca cctactgcta
    31861 atacctcttt actatcatct cttattgcga caactgatgg ttctctaaca acaatacctt
    31921 gtccttttat gtaaactaat gtatttgcag tccctaaatc tattcccata tcctttgtca
    31981 tcttattaaa actaaaaaaa cctttttttt ctttcttttt ttccttagcc atgattttac
    32041 tccttcctac tattaagaat catgtttaaa acattctcct attattttat cacatataaa
    32101 gtcaaattat catattttct ttaaagctaa agtataatcc atctccaata attatatggt
    32161 ctattatttc tattccaatt atttctccac atttaataag tcttgatgtg atatttttat
    32221 cttctcttga tggttctaca cttcctgaag ggtgattatg catcactatt atcttacttg
    32281 cacttcttct tatagcttct ttaaaaacct ctcttggatg gactaatgac gagcttaaag
    32341 tccctataga tacatctaca tcagatatta tctcattttt tgtgtttaaa agaaccgctt
    32401 taaaaacctc tttttttaaa taccttaggc tatccatata atacctctgt atatcccaag
    32461 gattccttat tttatacttt ataggtttaa aactagctac tctagagcct agttctaaag
    32521 ctgctttaat ttgggttgat tttgataacc caattccatc tatattacac agctcctcta
    32581 ttgtcatatc ttctaaatgt ctaataccct gaatatctct atttattata tagttggcta
    32641 attcaatagc atttttattc ttgttgccag ttcttaaaag tatagccaac aactcagcat
    32701 ttgataagct ttttacgcct ttggcaagca tcttttctct gggtctttcc tctggtgcca
    32761 tttcttttac cttaatggtt gaattaaatg actttttcag ataaatcaca ctccataaaa
    32821 aagatttata ctaaaatatt tttttaatag gtcgcctaac cttgaaattg gaagaccaac
    32881 tatattaaaa taatctcctc taatttcttc aactaacaaa gctccataac cctgtatacc
    32941 ataggctcct gctttgtcaa atgactcatt agttttcaga taatcctcaa tatcctgctc
    33001 tgataacgtt ttaaatttca cattgctgat tacatagtca attacctttt tatcttcgca
    33061 caagtttatt aagctaatac ctgttatgac ttgatgctct cttccagata gtctttttaa
    33121 catatctctt gcacaagact catcttttgg ttttcctaaa atagcattgt ctaaaacaac
    33181 aactgtatca gctccaataa caacatcttc attatgttca gatgctacag acatactttt
    33241 ttcaaaagct aatctcataa ctaaatgttt tggtgtttca ccttccaata taatctcatc
    33301 aatttcattt ttaattatat caaatcttac attcgtattc tctagaattt ctttccttct
    33361 tggagaggct gatgccaaga ttatattcat ttattcacct catttgtacg taatttgtac
    33421 ctatttagtc tatcactata ttgtaaaaaa ttcaacagaa atgtcgaacc ttttttgtta
    33481 cactattgtt atatttatta ccattagaat aaatatacat aaaatagagg tatggaaatt
    33541 attccatacc tctgttttat gtactcatta gagatatgga aattattcca tatccttatt
    33601 ttgtccatat tacaaaattt taatagcttt ctttggacat ttttccatac ataaatggca
    33661 tcctacacat ttatctgcat ctaccttatg tttttctttt aattctccct ctattgcatc
    33721 aaacttacat tgttttttgc acactgtaca tccaacacaa agttcttggt caatagtaac
    33781 tttctttttc ttagttatgt cacctgatat tacttttgta gggcattttg ctacacattg
    33841 catacaacct acacacttat tagggtctat cttagctatt ttgtcttcaa atattattgc
    33901 atcaaattta caagctttta cacacattcc acagccaata catccagcag tacatttttc
    33961 tttaacagct ttaccaaact ctttgctatt acactctaca actacttctt gactttctgg
    34021 ttttgtgatt attataccct taggacaaac ttctttacat tttccacaat ttacacactt
    34081 ttcttcatct attactgcta ttccatcaac tatagaaata gcatcaaatt tacaagcatc
    34141 tttacatgtt ccaagaccta aacatccaaa tttacacatc ttagcacctg agtttaaaac
    34201 atttgctgct ctacaatctg atattccttc atactcatat ttatcttttg cacttgaaca
    34261 agttccttta caaataactt ttgctacttg tttctcacct gcttcagcac ttattcccat
    34321 tatttctcca acttttgcac caacatctgc tccacctaca gggcaaccat taactggtgc
    34381 attgccttca actatcgcat ttgcaagacc tccacaacct ggaaatccac aacctccaca
    34441 gttggctcct ggaagtactc ctagtatagc ttccactctc tcgtctactt ctacagcaaa
    34501 ctttttagat gcaaaatcta gtactatccc gaagattaag cccataattc ctaaaactaa
    34561 tacagctgta agtatcacca ttttcacccc tcttttttat agctttataa gtcctgtaaa
    34621 tcctaagaaa gctattgaca ttaaacctgc tgatataagc gttataggga aacctttaaa
    34681 tgcttctggt atatcagcta attctagtct ttctcttata cctgcgaata ttactattgc
    34741 taaagtaaat ccagctccgg ctccaaatcc gtttattatt gtttctacta aattataact
    34801 tttttgaaca ttaactagag ctataccaag aactgcacag tttgtagtta taagaggtaa
    34861 ataaactcct aatgcttgat ataaagatgg actcatcttt tgaattacca tttcaacgaa
    34921 ctgaactata gaagctataa ccaatataaa agctattgtt tgtaagaatc cagttccagt
    34981 ttttactaat aaaatctgta taaaataagt tataattgaa gctagagtta aaacgaacgt
    35041 aactgcaact cccatcccta ctgctgtatc aaccttctta gaaactccca agaaaggaca
    35101 tatacccaag aattgagatg ttataacgtt attaacaaga acgatactta aaaataaaag
    35161 tattaaattc atttattaca cctccactat gcttttttac ttcttaattt attaaatcct
    35221 gcaaataaga atcctaatgt taagaatgca cctggtggta atataaatat taatactggt
    35281 tggaaagatg ctccaaataa tgtcattcca aataaactac catttccaag taattctctt
    35341 actgcaccta ttattgtaag tgcaacagta aatccaagac cttgacctac accatcaact
    35401 attgaaggca tagctcctgt tttgaaagca aaactttctg cacgagctaa tattaaacag
    35461 ttaacaacta ttaatggtat atatatacca agagccttat caagagcagg aacatatgct
    35521 tttaaaagca tacctactat tgtaacaaat gtagctataa ctactataaa tataggtatt
    35581 cttatcttat ctggtgtaat ttttcttatt aaagatataa ctaaatttgc acatattaaa
    35641 actgctgctg ttgaaagacc cataccaatt ccatttattg ctgaagttgt aacggctagt
    35701 gttggacaca tacctataac ttgaacaaat gttgggttct catctattag cccattttta
    35761 aatactttag ctaaattcat aattaaccct ccttatttat taagagcact attgaaaaca
    35821 tctatagcag catttactcc tgtagtaact gctgtagatg taatagttgc acctgatatt
    35881 gctaatattt gattatctgc tgttgtactt ccttttgcta cttcaagagg ctcagcagtt
    35941 tttcctttgt attgaccctt aaatgcatca tccttagctt ttgctccaag acctgctgtt
    36001 tctgacatat taccaatgtc aacacctgta acttgacctt cagatgatat acctaccata
    36061 acttcaattt ctccaccata tccacttggt ttagctttta aagtatatcc aaccacttca
    36121 gaaccatcta aaccttcata cacttcagct ataagaccat ctccaaggcc tttgtaagta
    36181 tcttccttca tttctttaaa ttcttttgct tctggaagga ctgcttttct aagttcatta
    36241 tttgcttgta tatttctttg ttctattact ggagctgtaa cctgattagt agctccaaga
    36301 gctaatgcag ctattgcact tatagcaagt aaagtaccac ctaatctcac catactgttc
    36361 attatttagc cacctcccca aatactctat ttctaacaaa cttatctata agtggagcaa
    36421 gacagttcac taatagtatt gagtaagata caccttctgg atatccacca tacattctta
    36481 taacagttgt tataagacca gctaatacag cgtatattat ttgacctttt ttagtcatag
    36541 gcgaagttgt ataatccgta agcatgaaga atccacctaa cataagtcct ccagcaaaca
    36601 gttgatatat tgcgaaagtt atattaaatc cacctaaaag gaatgttaat ataaatacag
    36661 ttgctatgta aaatactggt ataacataat ttattatgcc tttatacatt aggtatactc
    36721 cacctaataa taataatatt gctgatgtct cacctataca tccaccaata ttccctatca
    36781 tcatgtcagc aagactaatt ccattgctag aaatatctgc cagtcctgct gctccatttt
    36841 tcaaaaagct taatggagtt gctgtagtaa ctgcatctaa atttttacct atccagttaa
    36901 cacctggttg agtccaagca gtcattgcta ctgggaatga tgctaataaa aatgctcttg
    36961 cagcaagtgc tggattgaca aagttacatc caattccacc aaataccatt ttaactacta
    37021 atattgcaaa tattcctcct actagacaca tccaccaagg aagtgatgct ggtacgttaa
    37081 atgctaataa taatcctgtt acaacagctg aaaaatctcc tatagtactt ttttgcttcg
    37141 taaatttttg atataaaaat tcagtaccta ctgtaccaag tatacaaaaa aacatagcac
    37201 tcaaagcatt aagtctaaag aagtatactc ctgctactgc tgctggaagg agtgctataa
    37261 taacttgttt cattatatat gaagtatctt cattacttct cacatgagga gaagatgata
    37321 ctatcaactt attttccatc gtttttcccc cttaactttc tttatttctg agcagcttgc
    37381 tttcttctct ttgctcctat ttctctcttt gctgatctta tagattgaag taatggtctt
    37441 cttgctggac aaataaatga gcaagaccca cattctatac aatccattgc tctatgatat
    37501 tcagctgtgt catagtcatc ttttaaagaa tatgcactta tgaaaagtgg ttgtaagaat
    37561 gatggacata catctgtaca tcttccacat cttaaacagt tttgaatatc tggagtacgt
    37621 gattcttcct catccaaaca taaaattcct gaagaacctt tgttagtcgc tatttcagta
    37681 gtatattgag ctattcccat cataggtcca cccattataa ccttaccaat cttcttatct
    37741 tctttaaatc caccacattg ttctattatt tctgaaacta atgttccaac ttttgttatt
    37801 aggttctttg gctctttgat gcaactacct gttattgtag tgattctttc aaccaaaggc
    37861 atacctgttt taatagactt agctatctgt gctgctgtgg caacgttgtc aacaactgca
    37921 cctgctgcta ttggtaatcc accagatgga acttctttgc ctgtacacgc ataaataagt
    37981 tgtttctctg ctccttgtgg atatttcact tgaaggccaa caacttcgat ttcgctatag
    38041 tctttagcta cattttgaat tgcttctata gcatctggtt tattcgtttc aattcctata
    38101 aatccttttt tgacatctaa taccttcatt aatgctctta aaccaaacac aacatcttct
    38161 ggattttcaa ccattaatct gtggtctgca gttaagtatg gttcacattc tgcaccattt
    38221 aatataacta cttctgcctt gctatctggt ggaggagata cttttacatg gttagggaat
    38281 gtagctccac ccatacctac tattcctgcc tcttttatga tacctactat atcttctttg
    38341 ctcaaatcct ctaactgacc ttttggttga acactctcat gtaattcttc cttaaagtca
    38401 ttttcgataa ctacacattg agctgaacct cctggtactt catgttgttc aatagcaata
    38461 actttacctg atactgaaga atgaacgtta catgaaacaa aaccttgttg ttcacctatt
    38521 ttttgcccaa actttacttc atcaccaact tcaacaatag gtttagctgg tgcccctata
    38581 tgttgctgaa gaggaatgta aactatcttt ggagcttgag ctttttcaag tgcctttgtg
    38641 ttagagtact cttttctata tggaggatgt atccctccct taaaagttaa gagtttcatt
    38701 gttttacccc cttatctata aaaaaacatt ttttctgcct tctataagta tactatatat
    38761 attaaaaaat cttaacaatt gttaaaaaaa tatccgtatt tttataattt attttataaa
    38821 tcaacacctc tatattaagt caaattgagg aaaaggattg cttaattaaa caatcctttt
    38881 catatagctt tctaaagtcc aaattttctg tattttattt tatagaattt ataaacatag
    38941 agtactcctg catggatgat aaaagcagac ttttacttac actatatttt tcttcatttg
    39001 ctgcttttga agctgtatca attttttcat tcacattctt tacatactct attaaattat
    39061 ctttaaataa acgcatttca gaataatcaa tcttttcagc ttcttttgat atattttgtg
    39121 atattgcctt tctatttgtc aaaatagtat tatatttttc catatctaca ttattttcag
    39181 cattcgacca aaaacttgat tcttctttaa agtttgttat taatttattt aattctttag
    39241 atatactctc tatataagcg tagttacttg tatactctaa agacaacata ggtgcatcta
    39301 agtgtgataa aaatgcatct ggaaacacct ttcttacact gcttatctgc tttctaacat
    39361 cattttcatc aaaagaggaa taggtctgta ttttttttac tccatccttc tccataactg
    39421 aaaaaggtat gtcattatta actaatgatg tctgtatttt tttcaaatca tcattattat
    39481 ctattgcagc aacttgaata gtatacatat cccagccttc tatagtagct aatttgactt
    39541 cttctggctc tttagtgtta tttaccgctt tttctggatt agtttcttgt ttatcatctg
    39601 aattggtttg tgatttagat tttttccctt tttttattga atttaattca tcagatatat
    39661 ctttataagt tatatctgat gaattattta gaaatggtat tttagccgat acatactcca
    39721 atatcttgct atcttttatt tttgtataag aataatagcc aattagacac aagcaagcaa
    39781 tcgttataac atatttacgt aaatcaatct tatgtctatt attattaaat cctctgtata
    39841 tcgtttttct tctattcatt agtttgtccc tcccaaaatt atattattaa taaagtatat
    39901 ttttaagagt cacaatttat gaatataaat aattatttct tctaattttt taataagaaa
    39961 ttgtacttac taaacaaatc ttcttgcacc aagtaatact ttagaccaat atgaactagt
    40021 taaattatcc actttaacct tattaggatt agtctgagta ccactacaat ggataaattt
    40081 actatttcct acgtatatac ctacatgatt agttgttcca tcaccatcag tgtcaaaata
    40141 aactaaatct cctggtgcat aatttcccat agaaattgca cttccaaaat tagcctgttc
    40201 tctagaaact ctaggaatag aaacgcctac agaatgttta aaaacatact gtgtaaatcc
    40261 agaacagtca aatttatcag gtcctgaagc tccccattga tatggtattc caataagagt
    40321 atatgcaaaa tctacgattg ttgaaccttt tgctgtagat ttatctgaat ttccagtaaa
    40381 tgatggcttt gagttactat tagattgaga attttggtta gatgatgaat ttggtttttc
    40441 ttttgtatcc tcattagtct cagaaatata actggcactc acccatccaa ttgttccact
    40501 cgataacttt accttatacc aaccattact tttagctttt aattcaacaa catctccacc
    40561 atttaatttt cctattatag aatagcttgt cccaggacca cttcttacat ttaaactcac
    40621 agcagatgtt accttaccat tcttgccttc aattgattct tcgctagatg gttttttatc
    40681 agaattatta gtactatttg aattactaga attgttcgtt ccaacatctt ctgatgtttt
    40741 agaaatatat tggctactag cccatccagt aactccattt gatagtttta ttttatacca
    40801 tccattgctt tgttctagta actttactac atctccatta tttgctttac caactaatga
    40861 atagttagta cctgcaccac ttcttacatt cagtctagaa ctcacattta ctttaccatt
    40921 tccactaata gttgtcccac ttgaagttgg attattttga cttgatgtac cttcagacga
    40981 accacttgtt gatatgtatt ttgcacttcc ccatccaaca acagaactcg atacccttac
    41041 tttataccat ccattagact tttctaaaat ctctacagtt tttcccttgt ataattttgc
    41101 taccttatcg caatcagaac ttggtccact tcttatattc aaggcacttg ctgttactgt
    41161 tcccttttca agagcacttg catttatgga gctaacagat actgctactg ccccaattcc
    41221 taaagctgct atagcttttt tcactactat cactcccccc aacaaatttt tatagtcata
    41281 aattcataac attattatcc atttttagtc cctacaattt aatgataact tattttctta
    41341 ttaattgtaa agaaattata aacatatcct taaaattagt gatttttagg aagtatttca
    41401 atccaataat tatctgggtc cgctataaaa taaattccca tactttcatt ttcaaaacat
    41461 atgcaatcta aatctttatg aagttttttt gcctcatcaa actcctcaac ttctaaagcc
    41521 agatgaaatt cattgtctcc taaattatat ggtctatccc aatctctaag ccaagttaat
    41581 tctaatgtat gactagtaat gccatctcct aaataaacta atataaaact tccatcttct
    41641 gcttccttgc gctttacctc tttaagccct aaagcttttt tataaaaatc taaacttttt
    41701 tctaaattag taacattgaa attgttatga caaaaattaa acttcatttt gaaatcactc
    41761 tccaattttt atttttttta tattatatca ttattataaa tttatttaaa tcatattaag
    41821 ttaaaaattt gaatgatgat gaccaattac caaatcatgg taaattattt aaaagaatat
    41881 gtcaaaaaaa gaataagctc tttcaaatgc ataaaaaatt tatacccaag ttatacttaa
    41941 tcatgcaaat tggcagaact tattctttaa aactctaact tttaagtttt tctttaataa
    42001 tataatttat tacttttttt ctaatatctt cagcattata atcatcttct acttctatat
    42061 ccaaaagttt tgctattgac ctcatatctt ctctagtctt tgacctatag cttgatatta
    42121 attcatcttt tattttctct ggttctaaaa gatattcttc atctcctctt ttgaaaacaa
    42181 cgtatttttg agcatatgaa cttctattgt agtatatata tcttgatatt tttcttaaaa
    42241 tttgattata tgaaagtcgc ttgttaatat caagttttaa gtactctgaa aaagcaaata
    42301 gctctttttt tgatttaaat aatgcttctt tctttatagt tcttgatatt gaagttacac
    42361 tttcttgata tgcacacttt tttaacattt ttaaatatac tctattaaga ccaatacttt
    42421 gattgaattt ttttatatta ttattaataa tcttatccaa gttaccttca aagtattttt
    42481 ttgctccttt ttgtgataca taactctcaa gttctttgtg ggccatatca agtatcattt
    42541 tttttaaatc ctctttatat cccctagatt ccatgatact ccctccctta gctatttata
    42601 gtatattcaa aaagctcaag aaatgtgagt cattacaaaa tttttttact ttttatgtat
    42661 atattaattt aaaaggggag ataatagtaa tgtaaaatca aacatactca atctccccca
    42721 tttttagacc tctattactc ccccaataga ggtctttttt tagtttatca atttctattc
    42781 aattcccttt agttcaaatc ctaattctgc tatcacttct tttaattttt caatagatac
    42841 atcatctttc atatctacag atgcacactt attttctaaa tctacatcta aaacttcaat
    42901 accatctata tcttctgtta atgcagtttt aagatggttt acacaatgac cacaactcat
    42961 accttctact aatagtttct tcttcattta attacctcct tataccctat aagggtattc
    43021 tatcatatag tttatacttt ttaaatagaa attaatcatt taatttgatt cattcgattt
    43081 tatatctaaa ttagatattc cctcatatac atcaaaatca tttggagtaa ttttaccttt
    43141 taatctacta ttacttacaa tatagttgtt tctcacagct aaacttataa atgttgcatt
    43201 atcttttata tatgtctgta catctttgta tgcttttttt gtttcaattt cagacgtaga
    43261 acttgtaagt gcagacatat atccatttaa cttatcatca gtatatccac tactcgctat
    43321 aatactactt gcatctggta taattgatag tttccatcca actaatgcta aatcataatt
    43381 tttagaatta agagcatttt ccatatcctt atctgacagc tgatttactg tactatttat
    43441 tcctatagct tttaagtttt catttattat gtttgcagtt tttattctct cactattatc
    43501 tctgtttact attatcttta agttcatttc agaaagactt ttctttactt cctctttttc
    43561 tctatttttt ttctcttcag cttctttttt gattctatct tcttctgctt ttttagcttt
    43621 tgcttcttct tctggcgtaa gcttctttga gttcttttta gctgattttt tctgattttt
    43681 tactttattg tcattttgat ttactgagtt tacatttgca tattctacct tagcaagaca
    43741 ctctatcgcc ttatctttat taaactctaa atccttcatt tcactattat agtattttga
    43801 ttttgaatta agtggaaaat taactggagt agcatcatcc atataacctt cactaataat
    43861 tctatcttta tctatagagt gtgcaattgc ttttctaaaa ttaacatctt tgaaaaaagg
    43921 attattataa ttaaataata cacactcata atctcttcct tgatattttg ttatattaaa
    43981 ctctttttct tgaaacttac ttaaatcatt taatgtaaca ttggttatat cactatcaag
    44041 agccataacc atagatgtcc ttgcatcttc attaggcacc atacctactt ttatgttctt
    44101 catggttttt ggaacttctt catagtaatc tttgtttaca gataaaacca ttccttctct
    44161 ttctgtatat gattctattt tatatttccc atttcctatc atattattat tcttgtcatt
    44221 tacatctttt gaatctaaat gattttgaga tacaattgga aaaattaaac tatcaattga
    44281 aaaagcatat ctagctttaa attttattgt aaaatcttta tctgatttaa tattcacaga
    44341 agctatattt ttagtaaatt cattatatgg actatctgca cttttttgaa ttaaaccaat
    44401 agtatagttt acatcatttg aagtaatatt ttttccatca tgccactttg catcttttag
    44461 ctttatatct atactcattc catcctgagc tatattatac tccttaacta attgaggaat
    44521 tacattgtag ttctcatcta tagtaaataa actatcataa actaaattca ttatataacc
    44581 aacagactta tcagtattag ttataggatt tatagttttt ggagttacca ttgttaagtt
    44641 tatatactta gcatctatag aactttgact ttgtaaactt gaatcactac tactttgttt
    44701 tgttttagta ttactacaac cagctaccat aagagttata gctaaaacga ctgttaagac
    44761 ttttattctc ttcattagtt ttttcctttc ttgccatata tcttattata atgttcgtaa
    44821 ttatttttta ctttttctac atattttgaa gtttgcttaa aaggtatatc atgtagattt
    44881 tcgccatctt tactatattc attattttct aaccattttt tcacattacc tgaaccacca
    44941 ttatatgcag ctatcactaa atctaattta ccaaattctt tgtataactt acttaaatac
    45001 caacagccaa gtcttatatt agtctctggg tcgaaaatat ccacattttt taaatttagt
    45061 tcctctgctc cccaatctct agttatgtct aatatttgca ttaatccttt tgcttccttt
    45121 tttgaaacag cagaactatt aaacttactt tcggctttaa taacactgta aactatattt
    45181 tcatctaaat taaattcttt cgaatacttt tctacatact ctgaatattt tttaggatat
    45241 aaaaatttat gtattacttt gctttccatt aatagtgccc caaataagat tataaaaata
    45301 gatagaatca atactttctt actattcacg ccaattctcc ttcatgtact caataaattt
    45361 atgtgcttta ctttctaatt cagttattgt tcccgaatta tctattatat aatcaccata
    45421 tttggatttt tcttcctgac tcatctgtga atttatccta ctaagtgctt cctgctcact
    45481 gcaattatct ctcttttgta ttctactaat ttgtacttct tgtttacaag taactactaa
    45541 tagcttgtca accatatcta aaaaaccact ttctaccaat attgccgcat ctaacactac
    45601 tatattttcg cctttttttc tcaatttttc tatttcactt attatttttt ctcttattcg
    45661 tggatgagtc aagttattta attccttaag tttttcttca tcactaaaaa ctattttccc
    45721 aagagctttt ctatttagag ttccatcatc attttttata ctttgcccaa aatggacaaa
    45781 tactttttcc aataacaact tatcctcaaa tatcttcctg gatataatat cagcatccac
    45841 tataggaatg ttaagatttc taaatatatt tgataggctg ctttttccac agcctattcc
    45901 tcctgtaagt cctaatatca acataaaatc acctactttg tctcatacca agaactacct
    45961 acatttaaat ctacatctaa gtgaacatcc atatttacag cattttccat ttcttctttt
    46021 actattttct taactatatc tatttcatca tcaattgctt caactatcaa ctcgtcgtga
    46081 acttgtagta taagttttga tttcaaattg ttctcttcca attttttatg aacatttatc
    46141 atagcaattt ttattatatc tgctgcactt ccttgtattg gtgcattcat tgcaaatctc
    46201 tttcctctat ttctttccat aaaattgctt gactttattt ctggtatata tcttcttctg
    46261 tttaaaattg ttacagcata tccatcctca ctagcctttt ctactgttgt gtccataaac
    46321 tcttttattt tatggtattt agcaaaataa ctttcgatat attctttcgc ctttggaaca
    46381 ggtatattta aatcatcagc tagaccaaag tcacttttac catatataat accaaagttt
    46441 acagctttag ctgcacctct caattcacta gtaacatctt ccataggaac attaaaaact
    46501 tgtgaagctg ttttggtatg aatatcttca tgatgtttaa atgcttctat catattttca
    46561 tcctgactca tatgtgcaag aactcttagc tctacttgtg agtaatcggc atcaaccaac
    46621 ttacagttat catctgcaat aaacactttt cttatttttc tacccatttc catttttata
    46681 ggtatatttt gaagatttgg ttctgtagat gaaattcttc ctgtagtcgt tatagtttga
    46741 ttaaatgatg aatgtattct attactttct ggatttatta tatttaaaag tccttcaacg
    46801 taagtagaat ttaactttac tatttgtcta tactcagtta tcttatctat tattggatgc
    46861 ttatctctta atttttctaa aacatctgca ttagttgaat atccagtttt agttttttta
    46921 attattggaa gctctaattt ttcaaataat ataacaccca attgttttgg tgaatttata
    46981 ttgaatggct ctcctgataa ttcataaatt tccttttcta atgtagctat tatttcttta
    47041 aattcaacac tcaattcatc caatatactt ttgtctactt ttataccttc atactccata
    47101 tgacctaaga cttctactaa aggcatctct acatgataaa aaagaccatc catactcata
    47161 tccattagac ttctttccat cataggaact gtttctttaa ctgtgcatat tatttgaccc
    47221 atatactctg ctaaatcctc aaattctaaa tcctcatagt ttttagattt aacacccttt
    47281 cctaataatt cttcttttga tttaaccttt tttgataaat acttcatagc tattgcacta
    47341 caatcatatg aggtagatga agttgaatct attaagtact cagctattgt tatatcaaaa
    47401 tacatatttt ctaagtttat attatatggt tttaaagata tataatcatc ttttaaatta
    47461 tatccatact ttttaatttc attatttgaa aatatactat ctaactttga cacttcattt
    47521 gaatctacat aatatatttt ttctccatct acacttataa aaatatatat tatatttttt
    47581 tcaagtatat taccttgtcc tctaacagtt tttaaaataa cttgtccttt tttgtttact
    47641 tcatctataa atttttctat atcttttaat tttaatattt ctattttttc ttctacgtgt
    47701 tctgtgtcat ctgaatcgac caaatcaact aatcttgata agagacttgt aaatccaaag
    47761 tatctaaatt tatctaaaag ttcatcttta tcataatcgc caaaaatcat actatctaaa
    47821 tccacttcta ttggcacatc tcttataatt gttgcaagtc ttttactttg aatagctatt
    47881 tctttgtttt cctctatttt cttttttaca ctacctttaa gcttatctgt attctctatt
    47941 agattctcta tactagaaaa ctcttttata agctttatac ctgttttttc acctattcca
    48001 ggtactccag gtatattatc agacttgtct cccataagac cctttaaatc gataaattgt
    48061 gttggagtca tctcatattt ttcaattaca gaattaaagt tgtattcttc tacttctcca
    48121 accccttttt tcgttataag ggtagttgta ttatctgaag caagttgaat agcatcttta
    48181 tctccagtta ctatgtatac cttatatcca ttttcttctg cttttttaga aacagtacct
    48241 ataatatcat ctgcctcata accatctatt tctagtctat ttattctaaa tttatctaaa
    48301 aggtctttta atggctgtaa ttgttctgcc aattcatctg gcataccctt tcttccagcc
    48361 ttataatctt tatattctaa atgcctaaat gtaggtgctt ttctgtcaaa agctacactt
    48421 atatgtgttg gtttatatat atctatcatt ttaaatagca ttgtagtaaa cccatatata
    48481 gcattggtct ttaacccttc tttattattc atttctggaa gagcataaaa agctctattt
    48541 attattgaat ttccatctat tataattaat tttttttcca aattatatca ctcctaaaaa
    48601 ttatctattt ttgtaacata tatattatat accaatatag tgttatttaa tattcccata
    48661 ataataatag tatattaaaa ttaaatatgt tgcaaacaat atattttttt gctataataa
    48721 tatacatgac atgcccgagt ggtggaattg gtagacgcag tggactcaaa atccaccgga
    48781 ctaatactcc gtgccggttc gagtccggcc tcgggcacca ttaaaaactc ctaaagctat
    48841 ttattcaata gattaggagt ttttttattt ttgatttaaa ttttaagtta ttttttgaaa
    48901 ttactgtgtc tttttaaaat ttatataatt atataaattt atcttctagc attaatttaa
    48961 aaactaattt acttttatat aattttctat tttatatcat aacttattac aaccttttat
    49021 ctaatttatt gtatacaaca acactacaaa taaattgaaa taaaataagc aatccaagaa
    49081 caactaaaac ccacttgctt attaccatta cagaaaatac actcaatata gaaacaataa
    49141 atataagaat tacaagaaca tagcacatga tttgattagt aatacgtcca gctttatcac
    49201 gtaacataat tcttctttca tcattcatct ctatcctttg attttttatc ttttcttcat
    49261 aatctactgc tctttcaggt ttactccaat acatatattg aagaatcata catacacctg
    49321 gacctaaagc agctccagat aatccccaaa taaaagcctc aaatgaaaac tcagtaaatg
    49381 tagccaataa aacaagtaaa attccacaaa taaaatatat aattccaaca tataacatat
    49441 tctttttcat ttttactcct cctcataaat aaatatttct tcaatactca tatcaaagta
    49501 tctagctatc ttaaaggcta agatgataga aggattatac ctaccatttt ctaatgaacc
    49561 tatagtttgt cttgatactt gcaaaataga agcaagttct tcttgtttta tgcctctttc
    49621 ttttcttatt tcttctaatc tatttttcac atctatcccc ctttaatatc tcaactacgg
    49681 aaagtctact ttccataatt atacaactat attccattta tgtaaagctt actttccata
    49741 tttacaaaaa aataacagac tattttcagc ctgtaatttt agaatttcat gttgtttatt
    49801 aattttaatg ttatttatta attccatatt atttattaat tttaacttgg tttctgaatt
    49861 ggaatccaaa cttctgtagt ataatcagga gcattgatat cgccattggg ataaagttca
    49921 atatctggta aattagcata cacataccca gaacttggta accactcagt aataattctt
    49981 ttttgcaatt cctgtattgc cagagcattt ggcattggag aaacacattc aaatactgcc
    50041 catgtgcctg atggtattaa gtattcatga gtatcttcta atacaggctt atctgttgga
    50101 gcagcaatat aataatctaa acccttacta tttgtacaca cactaactcc aagcaatcca
    50161 caaggttcat tatttattaa ctctgaaagt ttatcaattg ttccattttt tatgcattta
    50221 gcccacaact taggaacttt ctcaaagcac tcttctacaa tcatgttcat actttctttt
    50281 ataccaacaa tacgaaaccc tttcttttct acaatacgat attgcatttc tatatttcct
    50341 tttacataaa tgcttaatgt catcttagga tatgctttta aaacaacacc ctttgctcta
    50401 gatgcagatg gagaaatgtt atgtatattt tgaaaagctc tattaaaaga tgttggtgaa
    50461 tcgtaaccat acttctcaga tagttctaaa attttgatgt tactgttctg aagttcaaat
    50521 gcagccttag tcatacgtct tcgtctaata tattcagata atggtacttc tgcaatatat
    50581 gaaaacattc tttgaaaatg aaaggttgaa caacatgcaa tttttgctgc ttctgcataa
    50641 tccactccac tttcgagatt ttcttcaata taagtaatag cttgatttaa tttatttatc
    50701 cattccattt gatattacct ccaagcaaat tatacagttt aataaaataa tatacctctc
    50761 tattcatgca caaaattgta agcatttaaa tttataagca tttttcaatc aatacaataa
    50821 atataaaaat tgtattatac aataaaaaag ttcaataaca ttatattgta aaatgttatt
    50881 gaacttttta taaaaattaa tttaagtgta gttaaattaa gtattacact atcttatata
    50941 ttacaatatc ctactatctt atagtcttct ggcactttat aatctttgtc tggagtacct
    51001 aaattccatt ttaaatcaaa catagttgca cttattattg ttgcaaaata aagcataact
    51061 ataccaatgt ctattttttc ttcatataaa ttagtatgac catcttttct aacagctaaa
    51121 actacagtgc ctccatcaac tataaatctc catggttgtc tatttaatgt agatggagct
    51181 aatcttgcat agtgaaatgc atcaagaagt gctctttctt ctaagatttc tatacttgca
    51241 acatttcccc attcgttcat ataaacaaca tcttctacac ctagtctagt agacccctta
    51301 tctgttacaa cttgcatatc agattttgaa taattttgcc cagtttttgt agcatttaat
    51361 actttagcat tacttacatt ttctccatat ccaatagcta taattcctgt tacctcttta
    51421 tctgaattaa ttccaagttt ttcttttacc ttttttccat cttcaaaagt aacccaacaa
    51481 gaaccaattc caagttctgt tactttaaag attatacttt ctcctatgta ccctgaattt
    51541 tcaatgtaat tatcttttat gtcagataat attataatat aacttggaga atctatcata
    51601 tttcctttgt accctgctac tttatctaaa ttattaaaaa cttcacttct attcataatt
    51661 cttacatcaa catctatttc tggaactagt ttcttacaag attctgagta tttcttaatt
    51721 tcactaagat attcttcttt aatatctgtg ttcttatatt ctctaacaga ctttctattt
    51781 aatatgattg ttttataatc cataatttta tcctccccaa actagtattg tcttaattat
    51841 atacccatta atatattatt ttactcattt atttaataaa taaagattac aattttgtaa
    51901 ttattattta ttaataatat tccactttta cattaataat gaccagttgt gcaaaatcca
    51961 ttgccaacca ccaaataaaa acatattata aaggtaatat aaaataacaa acaaatctta
    52021 acaaaaaatt aaactttttt tacacgaaag aaggcttccc gttgccttct ttatttttat
    52081 aaaaaaataa gctgtttcta aaatgatttc acatttttga aacagccaag ttattctata
    52141 atgacaacta taatttgagg atgtgaggga gagttgtcat tataaattta gggtaattat
    52201 attatgtttt aagctagttc tttctatatt tatataatac attttatata tgaattttat
    52261 atgagattgg tataaatgat atatgaaatt acatatgttt atattatatt aaattttatt
    52321 attacatttt ccacaacaat actcatatgt ctccacatta tttggaatat ttacaaatac
    52381 aaattcttta cagttctcac aatactttaa tatagatata gttccacaag tgtaacattc
    52441 aaatattaca caatcctcat tttcctctac tatttcaaac tttttactat gttcaccaca
    52501 ctctgggcac ttgtgattat ttacattcat aaatactcct ccttattagt atagttacat
    52561 gtcaaaaact taattaatgt attctatatt acttattata tattctataa taaatcatat
    52621 tctaatataa taaaacaaat taaataaaaa aaaaaccata aattttaaat ttatggatta
    52681 attcttgtaa tgataactct atttgaggat gtgagggagg gttatcatta caatagggta
    52741 ttatattatg gtttttaagc tagtctttct acacctcata tgatacatat gctatatgaa
    52801 ttttatatga tttttacata aatattttat gaaatttaaa ttttttagtc attttgaaat
    52861 ttgtaaaaag ttctctaaaa atccacagca tcataaacag ccaaaattta agtaaaacat
    52921 cataaaaaaa tttgtccaat aattttaaca agtaatctca cctcattata attattgaca
    52981 caaacttaaa taaacaatct ataaatcttc tataaatctt aaactttccc cctattgata
    53041 cacaatttct agtttgtcaa ttttattttg catttctaag aaaatttctt caacagaatt
    53101 gttaaatata ttgcctaaat agattctttt atctttttga aatgaataag attttacact
    53161 accatcagaa gaaatatata aatgactcca ctctgctcca tattttgaaa acctctcctt
    53221 tgtatcttta aacctcatat cttctatttt tattgctttt tctctgtctc ctcttactac
    53281 agtgtgaccc ctttttatta aactggttat ttttatatct tcttttaatt taatacgtgt
    53341 atcatcattt tttgaatata ctttccatat cactttatga cgataattat ctaattcctt
    53401 tattaagctt ctatcaatag taaaactatc tttagttacc acaattaaat caaaatggtc
    53461 taacatatat tgaaatattt ctctcatact tttatttttt aaaatatcct caccaataac
    53521 ctctataaat ctacagcctt tctcatacat gcagttcaat aaacttgtga tttcagaaaa
    53581 ataatcattt gtattattat ctccatctat ttctatagta aagtacaaag gagtaatgta
    53641 tgatttattt cctgttatct caaatacact tgatagtgtc tgtatatcat cttcaaacgt
    53701 taagtacaca ttctcataaa acataaaaaa ttccataact ttttctttca tattatggat
    53761 atttctatat ctattggata atatatttat tatatcgtca gtagtatttt tcccatcaca
    53821 ttcagccagt ataacaattt gcttccaact taagctatcc acatttccga tacttttttt
    53881 atatccatct tcttcgtcat aaataggacc aattataatg ttttcttttg gccacagatg
    53941 aaccctagtt ccatctttta atttcggata tttatttttt acagactcat aaaatctact
    54001 tgtatcaccc atgattcttt actacccccc atagtttaaa tattctatgc taaaaatagc
    54061 actttatttt tattaattca acaattattc aaaattggtc attatatatg tttaaatgga
    54121 tttaacatca accttattta tatgttattg atgtttatat atgttatata aaatcttatt
    54181 tctcatactt aaatgtaatc ttaactatct ctggtttaca attaagccta attaaaactt
    54241 ttgagcctcc taagccttta tttaaaatca tagtgctatt atctttttca tattttcccc
    54301 agtcatactt aggaaagaac tctctatttg gagataatac acctccaaca aaaggtattc
    54361 ttattatacc tccatgaaca tgtcctgcta aaaccaaatc tgctccccat tttgcatatt
    54421 tttcaaagaa aaatggtgta tgtgctaaaa gaatgttata ttcattttca ttaactttac
    54481 ctagattgtc ttctacaaaa ttgtcactta gttctaattt tttgttatta gcaaataaat
    54541 atggatagca ttccaatggt ataattaaac catataaatt aagatggcta ttacctctat
    54601 atattcttac agattcattt tccatattta ttattttctt tgaatatagt tccttaaaat
    54661 aatccttata tagatgttta tactttttta ttaaagattt ttgttcatga tttccaatta
    54721 tatgatatac ttcatatttt tcaaccaaat tatctattaa atctaatgca acttgaaaat
    54781 ttttattttc tccatctact aaatctcctg ttataaatat aacatctggg tttaatgatt
    54841 caattttatc tatcaatacc ttattatttt tatcaaacac cttattatgt aaatcactca
    54901 cttgaactat tttaaagtta tcaaattcct ttggaatttt tttgttgaaa atagtatatt
    54961 ctgtcgtttc tatatgctga gtttcatact tatacag
//
LOCUS       DAEPHU010000020        53214 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 01A10CD0081
            SAMN05941466-rid12468953.denovo.020, whole genome shotgun sequence.
ACCESSION   DAEPHU010000020 DAEPHU010000000
VERSION     DAEPHU010000020.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941466
            Sequence Read Archive: SRR6291087
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 53214)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 53214)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068158.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 22:43:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,892
            CDSs (total)                      :: 3,805
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 87
            rRNAs                             :: 8, 1, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 55
            CDSs (without protein)            :: 55
            Pseudo Genes (ambiguous residues) :: 0 of 55
            Pseudo Genes (frameshifted)       :: 21 of 55
            Pseudo Genes (incomplete)         :: 28 of 55
            Pseudo Genes (internal stop)      :: 16 of 55
            Pseudo Genes (multiple problems)  :: 8 of 55
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..53214
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941466-rid12468953.denovo.020"
                     /strain="01A10CD0081"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            complement(<1..187)
                     /locus_tag="KR231_001281"
     CDS             complement(<1..187)
                     /locus_tag="KR231_001281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-binding protein"
                     /protein_id="HBH0003681.1"
                     /translation="MGENYKFFNHKDCEFFPCHKTNKPEEFNCLFCYCPLYALGENCG
                     GNFKYTDKGIKDCSSCIL"
     gene            404..1687
                     /gene="hflX"
                     /locus_tag="KR231_001282"
     CDS             404..1687
                     /gene="hflX"
                     /locus_tag="KR231_001282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase HflX"
                     /protein_id="HBH0003682.1"
                     /translation="MKEIQEKALLVGLNLTTIVKKNDDIDTNESMEELKELTKAAGAE
                     VVGSLIQNKHSVDAAYYIGKGKVEEIRAYSDSLDATLVIFNDELSGAQIRNIENVVGR
                     KVIDRTTLILDIFAQRALSKEGKLQVELAQLKYRLPRLYGMGGEMSRTGAGIGTRGPG
                     EQKLEIDKRHILNKAADIRRELKEVKKNRETQRVKRLKSNIPIVALVGYTNAGKSTLL
                     NELIKTHKDYEQEKEVFVKDMLFATLDVTLRKALLPNKKEFLVVDTVGFVSKLPHDLV
                     EAFKATLEEVQYADLILHVIDATNTSYELQKSTTEGVLKELGVNDKKHILVYNKVDKL
                     ELDIYPKSQEDIVYISAKQGINMDKLLNMIEIALMENTYSVSLMLPYERGDIFSRIKD
                     KYNVENFEYGESGITLDVDLDEEDFNIYREYILEK"
     gene            1695..2372
                     /locus_tag="KR231_001283"
     CDS             1695..2372
                     /locus_tag="KR231_001283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HEAT repeat domain-containing protein"
                     /protein_id="HBH0003683.1"
                     /translation="MDINWENIDNLEDYFITYLLYKESKTVSQISKIRNISSTEASEQ
                     LIQAKLKIKEMQKDDFEASKDILDKFLELDKIKRLDFMDSLDDEKMVYFKRKVFKRIL
                     VEKNAEDLIVLIWATGELKDDRFLKLLHQLTNHRHSDIRRITYSAIRKIESPSSREVL
                     QKGLYDKNAQTRQYCAKALSKLGDENSLKILQQLKDKNKNFEKEYVLRAYDKAIKSLE
                     NAKNLKK"
     gene            2458..2901
                     /locus_tag="KR231_001284"
     CDS             2458..2901
                     /locus_tag="KR231_001284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HBH0003684.1"
                     /translation="MIVRRCAGGVVFYANKVLIVKNDRGEWTLPKGKILGGGLPYESA
                     VQRVKVETGIDAKMIDVAGDTMYEFFSRSRQQEVCNAIMWYVMEACNTDCVLAPEFQE
                     GGFYKVKDALEMLSHHKEQALVEVSYKKFKELKKLVSEGDDVPAN"
     gene            3206..3850
                     /locus_tag="KR231_001285"
     CDS             3206..3850
                     /locus_tag="KR231_001285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YigZ family protein"
                     /protein_id="HBH0003685.1"
                     /translation="MSNYRTLHEFGMDEITIEKSVFIGYAKPIKSEEEALEFINEIKK
                     KHKDATHNVWAYTVGKNMNIQRYSDDGEPQGTAGIPTLEVIKKEDLRDVAVVVTRYFG
                     GTKLGAGGLVRAYTKGAKLGLEAGKIIYKVMYQEVKVKIDYTQLGKVQNELMNLGYFI
                     KDTVYEDNVEIVVYSRLEDVEKLSEKMIDITSGTGKIVLGEEFYLSEQNGEILI"
     gene            complement(3936..4313)
                     /locus_tag="KR231_001286"
     CDS             complement(3936..4313)
                     /locus_tag="KR231_001286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfite exporter TauE/SafE family protein"
                     /protein_id="HBH0003686.1"
                     /translation="MLFALIGFFAGIIGGMGMGGGTILIPALVLLAGIDTKIAQSVNL
                     LSSIPMTLIALAIHIKNKNVIFKLVIPIAVFGVLGAVFGSLLANYLSSDILKKIFGIF
                     LLLVGLFEVKKGFCAKSDKKPLN"
     gene            complement(4313..4699)
                     /locus_tag="KR231_001287"
     CDS             complement(4313..4699)
                     /locus_tag="KR231_001287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfite exporter TauE/SafE family protein"
                     /protein_id="HBH0003687.1"
                     /translation="MKKTDDLKKKYFDFNLKNTIIGVFTGFINGVFGSGGGTLLVPIL
                     NDIVKVEEHKSHATALSIIIFLTTASSVLYVSKGTYDVNLTIKVAVGSILGGIIGAKL
                     LNKVTGKFLRISFGIIMIIAALRMVF"
     gene            4878..5633
                     /gene="nadE"
                     /locus_tag="KR231_001288"
     CDS             4878..5633
                     /gene="nadE"
                     /locus_tag="KR231_001288"
                     /EC_number="6.3.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(+) synthase"
                     /protein_id="HBH0003688.1"
                     /translation="MSNIKIQIDKTVEWLINKVNEANAKGLIVGVSGGIDSAVVANLI
                     KKAFPENSMGVIMSIKSNPQDREDALKVIEGCDIEYLDLDLIEPQSAILDMVVGNLKD
                     KHLYREEYLKMTDANLRARVRMSTIYTIANNLGYLVVGTDNAAEIHTGYFTKFGDGGV
                     DILPIANLTKGEVYEWAKELGVHEDLINKAPSAGLWEGQTDEDEMGTTYNMIDAVLEG
                     RLDEVPKRDQEIIERLHRLSEHKRKTPAQPPKF"
     gene            5716..6435
                     /locus_tag="KR231_001289"
     CDS             5716..6435
                     /locus_tag="KR231_001289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YebC/PmpR family DNA-binding transcriptional
                     regulator"
                     /protein_id="HBH0003689.1"
                     /translation="MGRIGNIINRKGKQDAQRAKIFTKHARAIAVAAKEGGADPEYNA
                     ALKTAIEKAKADNMPNDNIDRAIAKGAGAGAGEDYETIVYEGYGPGGVAVIVETLTDN
                     KNRTAGNVRYYFDKNGGNLGTSGCVSFMFDKKGQILVGLGDGVSEEELMDVALEAGAE
                     DFITEEDGYEIITTPEDFSSVRDELKAKGYEFISADVKMIPQTTTVLTEESHLKMMNK
                     LVDMLEEDDDVQDIYHNWEVE"
     gene            complement(6602..7606)
                     /locus_tag="KR231_001290"
     CDS             complement(6602..7606)
                     /locus_tag="KR231_001290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="substrate-binding domain-containing protein"
                     /protein_id="HBH0003690.1"
                     /translation="MATIKDIAKDCGLSSATVSYVLSGKGNERRIPLHTQELILNSAD
                     KLGYKRSTPIKHNNIKIAFYWQDEGFELASTNILQAINHIISLEHLNINIIIRPYKVG
                     HLCDDEYFFANNYYDGIVLTGINADDIEYLVKNKPKIPVVVVNREIPGFSSVSIDNEE
                     TGRIAALHAIQNGKNDIAVVFNPTSFTCMTLRGKSFLKTCKEHGIHLSDSIYYCSNKI
                     DSGYDIAQKMLAKNSLKKVIFCNHDVVALGMMNAFHESGIVIGEDIQIFAASNGPSRL
                     MARSIPPLTVIDLKMEETAERSLRMIIDTVTGRINGIQQQVIYPSIIYRQSSPAQNLL
                     "
     gene            7872..8768
                     /locus_tag="KR231_001291"
     CDS             7872..8768
                     /locus_tag="KR231_001291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA lyase"
                     /protein_id="HBH0003691.1"
                     /translation="MSKVNIFEVGPRDGFQNLKEFLETDKKLKIIDGLIASGIKQLEI
                     SSFVSPKAIPQMKDAKEVATYCVEKYPDVKLYALVPNLYGAKVAWECGIRDISYVISL
                     SETHNKKNINRTHEESIDELKKIMNTYPDMNICIGMATVFGCPFEGLPKIEDAIRFAK
                     RLWENGIREMNLADTIGIADPKQVRETISALVEALPECRWQVHIHDTRNMGMVNTLVA
                     IESGITTVQSTLGGLGGCPFAPGASGNTATEDLVYMLERMGYDTGVDFVKLLELSKYQ
                     KSFVNGVYSGHHVNIKSDSCNC"
     gene            8906..10168
                     /locus_tag="KR231_001292"
     CDS             8906..10168
                     /locus_tag="KR231_001292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0003692.1"
                     /translation="MDIIALLLFLGVIIIAFVRKNNAGILALAIGVIAVRIFGMDDKE
                     LYGAISNSMFTTLVGITLLFAIVNSTGALKLVAEKIVAASGKRVWLIPIAVFIAGFVV
                     AGVGPGAIPALAIIPAMAVPVAITVGYNPVMLALIGECGLMAGRMTPITPEGQIITTV
                     AEGVGIENVMPTILACQTLSTIVFSIVLFIIFKGYKLKKPINVIDSKQIEKFNIKQII
                     SLISIVVMIAFIIIFDMNVGLAAFAVSAVLIFFNIADEGECIKSIPWSTIVMVLGVGA
                     MMTIVDAAGGIDLMSNALSSLMNSKTATPIMSISAGLMSMVSSALAVVYPTMMPMCVD
                     IAKAVGGVDPLALIAAVGVGGSLAGVSPLSTGGALILAAMGSSKKDFNKEEQNKVFVQ
                     LFIMSAVGLLVIAVVSILSFNAITHLMN"
     gene            10244..11437
                     /locus_tag="KR231_001293"
     CDS             10244..11437
                     /locus_tag="KR231_001293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA transferase"
                     /protein_id="HBH0003693.1"
                     /translation="MKKGALSNIKVLDLTRVLAGPYCTMMLADFGADVIKIEMPRKGD
                     DTRGFGPFVNGESLYYANINRNKKGITLNLKSEEGKNIFLEMVKHADVVVENYRPGVM
                     EKLGLGYDELAKVNNQIIYGAVSGFGCYGPYSERPGYDIIAQAMGGLMSITGQEGGEP
                     TRVGNAMGDVLGGMNLTIGILTALNARKIIGKGQRVDVSLVDSVVSSLETGIQRYFDS
                     GQPELMGNRYASAYPYDSFKASDGSFVIGCGNDKLFEKLCKKVLFREDLLIDERFKTN
                     LNRCEHYKALKPEIEKWSIKHTIKEAVDLISEAGVPAAPIYNLDCVTTDEHIAKAREM
                     IVDISHPIIGNMKVNGNPVKLMTTKAKIDMPAPSLGESNEEIYNGWLGFDSDKIKDLK
                     ENGVI"
     gene            12066..12860
                     /locus_tag="KR231_001294"
     CDS             12066..12860
                     /locus_tag="KR231_001294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-CoA hydratase/isomerase family protein"
                     /protein_id="HBH0003694.1"
                     /translation="MESVMENLNNLKVEVKDKVCVITINRPKALNALNSDTLRELSQV
                     IDVVSENEAILGVIITGEGKVFVAGADIRQMQNYKSEEGRKYAGYAQGVFDKIEALEK
                     TVIAAVNGYALGGGCELAMSCDIRIASEKAIFGQPEVNLGVIPCFGGTQRLSRLVGTG
                     IAKELIFTGRQVNAEEAKSIGLINKVVPSDLLLEESMKMMNQIVEKAPIAIRYAKVVI
                     NKGIDMDLKNALELEKDIAGLTFATRDKQEGMNAFIEKRKPVFENK"
     gene            12955..14295
                     /locus_tag="KR231_001295"
     CDS             12955..14295
                     /locus_tag="KR231_001295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntP family permease"
                     /protein_id="HBH0003695.1"
                     /translation="MNTGVIISLVGIIIALSLLVVMVMKGINIFIIAIVCSSLVAITG
                     SLNVYDALKVDYMTGFVGFLQANFFIFLTGTLMGKIMEITGGAKSIAKMIVRWIGKDK
                     ALLSIPIACGILAYGGVSVFVVSFAVFPIALEIFKEADLPRRFIPAALTFGCSTFAMV
                     APGAPQIQNIVPASTLGTDIMAGAVNGFISCAVMFIVGSTILYKMVSKEKANGGHFIA
                     HESDIFDEAEATNSKRENGPNGVIALIPLIVSILIINVKVNGKAIVPIEVGVFIGALL
                     VYLLLNKYQDNTKIVGHVGDACKTTVVAICNTCAVVAFGSVVKSAVGFDFIVNAMTNI
                     PGPPIAGAAVGTTVIAGICGSASGGLGIAAPLLGPVFLAKGVSAAALTRTMAISSAAL
                     DSLPHNGYIVTVTNGLCKETHKDAYMPIFWVTVLTPFIGTIVAVLLFTMFPGLP"
     gene            14432..15664
                     /locus_tag="KR231_001296"
     CDS             14432..15664
                     /locus_tag="KR231_001296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418473.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA transferase"
                     /protein_id="HBH0003696.1"
                     /translation="MLNKPLEGVKVIDLTYFVAGPGTSKILADWGADVIKVEPSFGDP
                     GRKTGATMTMPIDDYNNPFYSTYNSNKRGLSINLKSETGIEIMDKLLSEANVFVSSYR
                     TGALKRLGLDYESLSKKHPHLIWGQINGFGDFGPAKDNAGFDTVAFWARSGAMLDIAE
                     KDTSPINPPIAFGDATTSCSLSGGICAALYQQAKTGKGQKVMASLFGQAIWNASSLLA
                     STQFSDEYPKTRKNAISPVINSYRCKDGKWIFLSILEHERYFEALCRLFGREDLIKEE
                     KFASSVESKKNATELINILDGEFAKFTQNEMVEKLTAADIAHEKIQHVNDVVTDEQAI
                     ANNYIYEHTSKDGNKTMLASTPVKFGNIEVNMTCDAPLIGEHSDEILRELGYSDSDIE
                     ALIESGIVTMNKEACEIC"
     gene            15704..16846
                     /locus_tag="KR231_001297"
     CDS             15704..16846
                     /locus_tag="KR231_001297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA dehydrogenase family protein"
                     /protein_id="HBH0003697.1"
                     /translation="MDFRLTEAQLMLQRVAKEFAENEIAPIAAETDKTGIFPRELFSK
                     MAKIGFNGIGTPVEYSGSGGADIEKVIVVTEIAKKCAASAAILSIHTIYAQAILKFGT
                     EEQKKKYLPMMAEGGCVGAFALTEPNAGSDAARAATTAIIDEETDEYVLNGTKCFISG
                     GGQAESLIIFALTDPSKGIKGMSAIIVDKGTPGFSIGKIEEKMGIHGSETAELIFDNC
                     RVPKSNLLGKEGKGFNIAMTCLDGARIGVGAQAVGIAEGALEESIKYSKERVQFGKPI
                     SALQGIQWYIADMATMVESAKLLVYYAADLKARGEKHTKEAAMAKYNASRTAREVTNL
                     ALQIHGGYGYMKDYPLERMYRDAKITEIYEGTSEIHKVVISRAVLG"
     gene            16857..17651
                     /locus_tag="KR231_001298"
     CDS             16857..17651
                     /locus_tag="KR231_001298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009899720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="electron transfer flavoprotein subunit beta/FixA
                     family protein"
                     /protein_id="HBH0003698.1"
                     /translation="MNIVVCLKQVPDTNEVKINKETGTLIRDGVPSIINPDDRNALEE
                     ALKMKDELGAVIKVISMGPPQAKSALKEALAMGADEAYLISDRAFGGSDTWATSTIIA
                     AAIEKVGKYDVIFCGRQAIDGDTAQVGPEVAEFLGIPQVTYAKEVKVQDDKLLVTRYT
                     ETGDYLIEAKMPVLLTAIKELNNPRYPSVKGILEAYNNGDAKITVLTLADLDVDTTQI
                     GLKGSPTNVYKSFVPVKDKHNEIIEGINKKEKAEKLIEILFDLKLV"
     gene            17662..18684
                     /locus_tag="KR231_001299"
     CDS             17662..18684
                     /locus_tag="KR231_001299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="electron transfer flavoprotein subunit
                     alpha/FixB family protein"
                     /protein_id="HBH0003699.1"
                     /translation="MMRAKVNQGINLNDYNGVWVIGEQREGKINPVTIELIGEGRKLA
                     DQLGKELAVVIAGYEVEKEVKELLHYSVDKVYYINDPLLKDFTTDGYAISIANLIERK
                     KPEVVLVGATSIGRDIAPRIAGKVGTGLTADCTKLEIDSTDNKLLQTRPAFGGNLMAT
                     IVCPKNRPQMSTVRPGVMAKAVRNESETGILEVVTPELTEKMIRTRLVEILPQEKKSV
                     NLTDARIIVSGGRGLKRAEGFELIKELADKLGAEIGASRAAVDSGWIEHSHQVGQTGT
                     TVRPELYIACGISGAIQHLAGMSDSKYIVAINKDAKAPIFSICDYGIVGDLYEIIPEM
                     IESLNR"
     gene            18783..20159
                     /locus_tag="KR231_001300"
     CDS             18783..20159
                     /locus_tag="KR231_001300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-54-dependent Fis family transcriptional
                     regulator"
                     /protein_id="HBH0003700.1"
                     /translation="MKEQWYKDIFARVLSMTDDGFIVVNRSGVIIDINDKYCDFLGKE
                     RKDIIGQNIQSIIPNTKMLDVMKNKYCEEGAIHHYSGGNTKEKSVIVSRSYVENDNGE
                     VVAGVAQVKFRLQSFDVAKKLMSEYMELQYYKEQFKDNCGFDKLIGENRDFIELKKTG
                     VKASKTNFPVLLTGETGTGKEVFARAIHNNSSRSDKPMVSINCAAIPEELLESELFGY
                     DEGAFTGAKKGGKKGKFLVANNGTIFLDEIGDMPLTMQAKLLRVLQESEIEPVGGLKT
                     IKIDVRVISATRKNLSKMVEEGLFREDLYYRLNVINIHMMELKDRQDDILLLANYILN
                     KLNVEYKELKVLSDKVKNCFINYTWPGNIRELQNVIKSAYAVSDDMVIMMCDLPSKMD
                     NISRVAQCNVDSNCSIHEMVENYEKSLIIDVLRKYNWKCSKAAEVMGIHKSLLYKKIK
                     KYEIELNN"
     gene            complement(20491..20835)
                     /locus_tag="KR231_001301"
     CDS             complement(20491..20835)
                     /locus_tag="KR231_001301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0003701.1"
                     /translation="MDQIKRLHELQQKSYLTKEEFEELKNNTYIERFELRDECDNSYI
                     YTFYTNDKCNDIKFIKSQFIVTLIKIGFLCECGGVFRQKKIVDEYDYGYNAIYKCDSC
                     GKELDKEVENYD"
     gene            21323..22333
                     /locus_tag="KR231_001302"
     CDS             21323..22333
                     /locus_tag="KR231_001302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4116 domain-containing protein"
                     /protein_id="HBH0003702.1"
                     /translation="MHEDKNDIFESIDTEDFDNKTEEECLELVRKNGLNLIYIKNQTE
                     EICLEAVRQNCNAIKCVQNQTEKICIEAVKQDWRMLEFVEEPTEEICMLAINQDGTAL
                     KYIENQTEELCLRAVEKNGAALEYVKEQTEEICIEAVRNSEFGLARVKNQTEKICMEA
                     VKHCSYNLKWVENQTEEICMEAVRQNGLDLKFVKNQTETICLRAVRQNGMALEFVKEQ
                     TVGICLKAVRQYGMALKFVKEQTEEICTEAIKQDKRALSFVKGDKEKYKALYDNNEPF
                     AKRYVRNVIEKENRALIKKGEENAKIKIAGKLYDRGMSFEDISDIVEIEISKLKVSLG
                     VF"
     gene            22444..22932
                     /locus_tag="KR231_001303"
     CDS             22444..22932
                     /locus_tag="KR231_001303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin family protein"
                     /protein_id="HBH0003703.1"
                     /translation="MKITVLYQTRSGNTERVAKLIEEGAKKVDGVDVKLMRLDNIDLD
                     YLNESKAVIFGTPTYLANTTWEVKKWFDEDSKKVNLAGKLGAVFATCDYICGGPDVAI
                     LTIVGHLMVKGMLVYSGGGSLGKPFIHLGHVHSIEGPELQDEKAIIFGERIATKAKEL
                     FA"
     gene            23108..25036
                     /locus_tag="KR231_001304"
     CDS             23108..25036
                     /locus_tag="KR231_001304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EAL domain-containing protein"
                     /protein_id="HBH0003704.1"
                     /translation="MVWHIEYEIFSAIIVIFLMVYFFRSKFIPTLQNKIYCALLIFSF
                     LFIISNILGSFCLNNIDKIPIFITFLLNQIYLLLLPIPAALVSFYVMAIIYQDIRYMK
                     KRLLFLSIPLIICIILSITNPFTHILFGLSKETGYIRGCGYVATFASFFFYAIYSAFL
                     SFKYRKAMHESKIWAIRGFLIVSIVAIILQAIFLQYLLTGTACACSLLLTYLSMQNRG
                     LIIDDLTGVLNRQSFIQELDLNINTEQSGFIITIALDDFKFMNETFGTKNGDIALKEV
                     GKYLIQIHDVNHVYRIGGDIFSIVVNSQLGIEPDDIIRKIEERFKKPWLVEEISFNLA
                     TSIAVVYYPENAETTEDVIVAIDFSIHEAKRSESRRVVYADASISEKIKKKHVIKNCL
                     KEALKNDGFEVYYQPIFSNSRGRFTSAEALLRLEHKELGFIPPDEFIPIAEQTGLINS
                     IGLVVFEKVCRFIASDEFEDLKLDNIAVNLSVVQCMQKNLADDLLYLMNKYNVSPTKF
                     KLEITETVAMGSFNIIKETMERLIDLGVKFALDDFGIAYSGVTNMLSLPFSVIKLDKS
                     LIWSMNEDSRHKLTVETIIALINKLNMKAVAEGVETIKCAEDLIAMECEYLQGYYFSK
                     PVPEDVFKNLLKENTFTS"
     gene            25213..25623
                     /locus_tag="KR231_001305"
     CDS             25213..25623
                     /locus_tag="KR231_001305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HBH0003705.1"
                     /translation="MNKKKILVPIDGTERSMHSLEFIKGIFKKDEVEVEIMNVKELVF
                     IDGISLAEEIKNSENLGRRILDKAAEIMGEYDVKVHFTFGYPGDEIIRKAKEDNVDFI
                     VMTKSTKKGLTRMIGSVTASVVKQAKCIVMIVPE"
     gene            25645..25947
                     /locus_tag="KR231_001306"
     CDS             25645..25947
                     /locus_tag="KR231_001306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIBC"
                     /protein_id="HBH0003706.1"
                     /translation="MNKKIVAVCESERSLNSLKTAANDLGFDLVYEIQENDNIKNELS
                     IYDIEDASIVLFVTSDSIESIEKIDRFIDREFYEVDPKYIIEDAKSIVSEILIDLN"
     gene            complement(26164..26856)
                     /locus_tag="KR231_001307"
     CDS             complement(26164..26856)
                     /locus_tag="KR231_001307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FadR family transcriptional regulator"
                     /protein_id="HBH0003707.1"
                     /translation="MKSLNATEKIIDYIKLNILNGTFKINSKLPSERKIADLFNISRI
                     PVRNAINILCKEGILRAVPYSSPIVEGFKKVDLFDDGEIYKNHNIQEFYVESLRARQL
                     IESEATKLAILNATSKELQKIKYTYLKSIEELDKVSHGLIEECYDADLQFHKEIILAS
                     HNPIFIKYYELIPKTVSSNQYFGFKYRNSLKDMISHHNKIMIAFDSKDSYLGYTSMYN
                     HLEDVIQLFQHD"
     gene            complement(26882..28069)
                     /locus_tag="KR231_001308"
     CDS             complement(26882..28069)
                     /locus_tag="KR231_001308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBH0003708.1"
                     /translation="MKKISNQKLLLLSIVTFFWFSQYVYIPFQNPYLSACNVSTNMIG
                     IIIGAYGISQCLLRLPVGVFADSINKHKIFILSGIFFAGLASLIRVFSPGGNGFLIAN
                     ILSGISSSTWISYMVHYTNFFSTEHQQKATSTIILVNNLGMLIGFVMSTLFYEKLGMT
                     ALCIMSVLSSVIGTILALNIKNHNSKKIPEKISIKKYLSICKDKRLVFFSFMALIQQG
                     IQMSTTMSFTTQILKNLGSSSTLIGLSSIFYMVCAVASSGFASTKFCTKYGPKFWIPL
                     VFILVSAYCFLVPTIKNINIIFVLQVLPGISTGILLSYLTSESMKNVPKHQKSTAMGF
                     FQAIYAIGMSVFPMIVGKISEYTSIQYGYFILAIIAILASILSYTYYKKVDLTLNYDI
                     IQS"
     gene            28405..30282
                     /locus_tag="KR231_001309"
     CDS             28405..30282
                     /locus_tag="KR231_001309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HBH0003709.1"
                     /translation="MDYKNIAQEILLNVGGKENVNEVTHCMTRLRFKVKSASKVNKDK
                     LSKTEGVITVVESMGQIQVVIGNKVKKVYDEVIKIVPQSNNVGKKNESQEKQGIINSI
                     LSAVAGIFTPTIPAIAGVGMIKGILSVLAMYYMNKNGVDIKETQSYIILNAMADSIFY
                     FMPIILGYTAAKVFNANKIISMVLGATLCYPTFTALMAGEESVRFLGLAVTKATYTSS
                     VIPIIIAIWALSYVEKVLEKYIPEVIKIIMVPTLSLVVMLPATLFLFGPIGIYIGNVI
                     NFSYKYIYELSPALCGAFVGGLWCVLVIFGAHRALLPIGISDVAQTGRQNLLAFAGAA
                     NFSQAGAALGVFFKTKNQGLKTISMSATITALFGITEPAIYGANLRLKKPMVCAVICG
                     AFGGAIMGMGGAYGNAFANQGVLTIPVYAEAGALGFLSYLGGCAIAFFGSAISTYLVG
                     FEDLEESSNKENSSIKVETKDGVIDITSPVEGECIELSEVKDDVFASKAMGEGIAVLP
                     TKGVITAPTDCEVASLFPTLHAIGLKLDNGAEMLIHVGINTVELNGKYFTKHVNQGDL
                     VKKGDKLISFDIDKIKKVGYDVTTPVIVNNTFDFGQVVSCKSSYVSTNDNIISLVLAG
                     N"
     gene            30592..31998
                     /locus_tag="KR231_001310"
     CDS             30592..31998
                     /locus_tag="KR231_001310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HBH0003710.1"
                     /translation="MNTGFPKDFLWGASSSAFQVEGAWDKDNKGKTVADYNSFKKSHL
                     QADTKVASDFYHNYEEDIELMKELGMKTYRFSISWARIIPDGEGEINQKGLDFYNKII
                     DKLIECDIEPFVTLYHFDLPFKLVEKYNGWESRETVYAFERFAKICFKHFGDRVKYWQ
                     PHNEQNLIVRVEERINIYDETDSWKIDKMRAQMDYNLCLAHALAVNACHEMIKESKIG
                     AAVSSSVTYPLTSKPEDIYAARMNDNFKVYYMLDMHHYGEYPGYYMKYLEKRNIVPHM
                     EDGDKEILKKAKMDFIAVNYYRTNCAEALPEDSQHPFGLREGTVDFSMYGLFKMSMNP
                     NLEASEYGAAIDPSGLRVALNEYWQRYHLPVIITENGLGAKDILEDGKIHDDYRIDYL
                     RSHINACKLAIEDGVEMIGYCPWSFTDLLSSSQGFNKRYGLVYINRTDHEILDLKRIK
                     KDSFYWYKEVIENNGIVK"
     gene            32026..32874
                     /locus_tag="KR231_001311"
     CDS             32026..32874
                     /locus_tag="KR231_001311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454252.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HBH0003711.1"
                     /translation="MYITKVLNNSLLLAKDDNDEEIILMGKGIGHNYKAGSELNEKDI
                     EKIFVLHDENIKKSIIQLATEIDAEYFGIAQMIIAYGIEKYNLKLMNHIYLALTDHIA
                     FAVRRFKEGIMIENHYLFEIKEFNPKEYDIGKYAITVFKEVLGLDLPEEEIGNIAGHF
                     INAQQDNPYSDRNKRSAKIVNAILQIVHYHFSIVYNKESFYYRRFVMHLKAFSQRFLA
                     NEPSREKIDFIYEQVQKNCKEEYECVKKVGAYMYKEYSRELPRQEELYLMIHIHKILG
                     ELCENS"
     gene            33376..34068
                     /locus_tag="KR231_001312"
     CDS             33376..34068
                     /locus_tag="KR231_001312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003020373.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBH0003712.1"
                     /translation="MNKVLIIDDDKDLCILLKKSISIEQIEANYCHSGRDGLVELSKQ
                     DYQLVVLDVMMPGMDGFETMEQIRKYSSIPILMLTSKSDNYSKVHGLRAGADDYLTKP
                     FEITEFTARVLSLIRRYTRFNPKNEEPQQLSFKGLLIDLDQHTVTTNGEPMLLPPKEF
                     GVLLYCARHQGKILTKQQIYEAVWGEPYVYDDSNIMAIISRLRKKIELDPSSPIYLQT
                     IKGIGYQFNTEV"
     gene            34065..35000
                     /locus_tag="KR231_001313"
     CDS             34065..35000
                     /locus_tag="KR231_001313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBH0003713.1"
                     /translation="MKMDEQTIILFLLLLSIGLLFLSIFAFSKLGHIHKRLKDIEEIL
                     ADVQIGDENRKILIKPCDVMAPLVYQLNEIVYDYENKLLSLKKSDKASKQLMTSLSHD
                     VRTPLTTLIGYLDAVHSGIVIEQEREEYLEIARRRAYDLKDYIDVLFDWFRLNSDEFT
                     LSIESVEIAELSRNILKDWIPIFHEKKLNFEIDIPENRLMVNLDPDGYSRVVNNLVQN
                     VLAHSKARQIKITMSEDSRMVLLRVEDDGVGIARENLPHIFERLYKCDKGRSEKGSGL
                     GLSIVSQMVERMGGQVSVESEIGKYTVFTVSLPLI"
     gene            35148..36071
                     /locus_tag="KR231_001314"
     CDS             35148..36071
                     /locus_tag="KR231_001314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013273760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH0003714.1"
                     /translation="MNNLIIETKNLTKQYGAQKSVSNLNIHVQKGRIYGLLGRNGAGK
                     TTTMKMLLGLTKPTTGEIKIFGQDIHNNEKKLLPRIGCLIESPGFYPNLTGTENLKIF
                     ARLRGIPKKNAVESALDVVGLPNNDKKLFSQYSLGMKQRLAIALAIMHDPQLLILDEP
                     INGLDPIGIAEVRTFIRDLCTERGKTILISSHILSEIALLADDIGIIDHGILLEEESL
                     AQLEEKNSKYIHFAVSDAAQAARLLETQLNLKNFKVADNYNIMLYDTDVSVAEINRAF
                     ILNNIEVSESHLCEDTLEDYFKKVTGGEGIA"
     gene            36055..36825
                     /locus_tag="KR231_001315"
     CDS             36055..36825
                     /locus_tag="KR231_001315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBH0003715.1"
                     /translation="MKELLDIISCEFSKLKRLKFILISILGACLFPIPATILIAKDNL
                     PFEQLFKLVVNFGYFLLLPIVLSIVASQLFFIERDNDVLKNLATVPVPKGKLALAKLA
                     VLLFISLFYSVAGLGATIIGGFIVGIVEGVAVKLGMSIAFGIMFFVTVLPVVVLIVYF
                     NRSYIFSIILSFVYAIFNFSISLNIINFEPNNPLLSVLPAPVIMRWWMAFWGDPTGEY
                     TVLRQPYLLSTPACVGILCLITIIAVLLICMIYKKQEN"
     gene            36835..37617
                     /locus_tag="KR231_001316"
     CDS             36835..37617
                     /locus_tag="KR231_001316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBH0003716.1"
                     /translation="MLDIITTEFQKIKRYNILWIGVVAVLFSALLAVFQVVSSHGSDP
                     LTYESFANGVIWNNFSLSFPFGITLIGGYLINREYTDQTLKNILTVPISLRKLLVGKL
                     IAVGGITVLLSLFSFLCTFILGLLFCNINISVILVVKSLVQILSVNLYCYVAVLPIIA
                     YFGRKQNAFLTGVGIAFVYGFCGVFVAGRNLTDFYPITAGLGLVGYNNGAGTVYQPLI
                     GAMTLIVILILTTILLVFTPNYDKVMTISKKKGIKHKKYSHK"
     gene            37994..38530
                     /locus_tag="KR231_001317"
     CDS             37994..38530
                     /locus_tag="KR231_001317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rubrerythrin family protein"
                     /protein_id="HBH0003717.1"
                     /translation="MNLKGTKTEKNLMAGFAGESEARNKYTYYASKARKEGYNQIAAI
                     FEETANNEKEHAKLWFKLLHDGMPSTEENLKDAAAGENYEWTDMYAKFAKEAREEGFD
                     KIAYLFEAVGKIEKEHEERYLKLLENLNEGKIFKRDEEVVWQCQNCGHVYVGTEAPEK
                     CPVCDHPKAYFNIKAENY"
     gene            38562..38951
                     /locus_tag="KR231_001318"
     CDS             38562..38951
                     /locus_tag="KR231_001318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor"
                     /protein_id="HBH0003718.1"
                     /translation="MKFSKQRELILNEILNNPVHPTADYLYENLKKDNPNLSLGTVYR
                     NLAQLTEHGFIRKVSIPGYPDRFDGRIDNHYHIICEVCGEVYDLESEVLNNLQELISE
                     ETDIKITSYNISFKGICNNCKRCSQVG"
     gene            38988..39374
                     /locus_tag="KR231_001319"
     CDS             38988..39374
                     /locus_tag="KR231_001319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="desulfoferrodoxin"
                     /protein_id="HBH0003719.1"
                     /translation="MCSEQKFFICETCGNLVGMIQSGGVPIFCCGKPMKELVPNTTDA
                     AVEKHVPVIEVDGNNVTVKVSSTTHPMTKEHHIAWVYLMTEQGGQRKCLAVDGEPVVK
                     FALNDDDKVISAYAYCNLHGLWKAEL"
     gene            39501..40943
                     /locus_tag="KR231_001320"
     CDS             39501..40943
                     /locus_tag="KR231_001320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418516.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-hydroxy-acid oxidizing protein"
                     /protein_id="HBH0003720.1"
                     /translation="MSIYKCSVCGYIYDESKNDKTWDELSEDWECPVCTKGRSYFGKI
                     STVYYEEDEKIAEDIVEDESKLNTEKEGDLNYLSTYLRRDDEVEKHMDIIHEMAVTGK
                     SIIEPMRTKLPVISWDDILIMGAQLNPLPLNEHDEVNTTTIIGKKAKKPMIIENPVYI
                     SHMSFGALSKELKIALAKGAAQNKTAMCSGEGGILPEEKEASYKYIFEYVPNKYSVTE
                     ENLKNSDAIEIKIGQGTKPGMGGHLPGEKVTEEIAKVRNKPVGQDVISPSCFEEIQSK
                     EDLKKLVDELREVSEGRPIGVKISAGHIEKDMEFIAYAKPDFVTIDGRGGATGASPKL
                     LKDATSIPTIFALYRARKYIDTHGLDIDLVITGGLRISTDFAKAIAMGADAVAIASSA
                     LMAAACQQYRICGSGKCPVGVATQDEELRKRLHIENSANRVANFLNVSLEELKTFARI
                     SGHKDIHDLSVDDLYTVNSEISNYTNIQHV"
     gene            41240..42055
                     /locus_tag="KR231_001321"
     CDS             41240..42055
                     /locus_tag="KR231_001321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HBH0003721.1"
                     /translation="MERLKIQVLVDNNTYIDRYFVGEPAVSYYIEIDGNRILFDSGYS
                     DVFISNAEKLNIDLGNLTHVVFSHGHNDHTRGIQFLENRYDLSTVELISHPNCFIPRK
                     HGEKSIGAPFSAEEIKNIFMYNPKDKPFNLSKNCVFLGEIPSINDFEKRAKIGKCKIG
                     DLWEDDYVLDDSAIVCKTDKGIFIVTGCSHSGICNIVEYAKKVCGDDRVIGILGGFHL
                     FELNNRLDSTIQYLDKEEIRMLYPCHCVSFKVKAKMNEILNINEVGVGLTISI"
     gene            42657..43841
                     /locus_tag="KR231_001322"
     CDS             42657..43841
                     /locus_tag="KR231_001322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453637.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0003722.1"
                     /translation="MQKSVKKAKVTGSMLAIFGVASVLFSSHAGGGFATGNQETQYYV
                     QYGWTAPLMAILAMIILTATMREVIIMYNNNNCRNYKDLFCELWRPYPKLEIIWEIYY
                     YLMVLIAVSAVIAGAAAVFQSIGVNYFVAVFIIGVVLLVFTIFGAMLVSKAATAMTIA
                     ILVCTLTIFIVGIKAKVPEITEILSNRTSFTPGYIKPILNTFIYAGFQSVVIPTLAGC
                     SRPLLKNSKEATKAMIISFVMNAIALGLAVTMLMGWYREIIAAGQTTLPTLYVAGQSG
                     NHTIYIIYNVALFLCLMSTGVTTIFGLVNRFEDHKALSFLSSRMKRRVFTACAIMVVS
                     MLISLTGLSNIVKYGYGYCGYLGLFTIVIPFLTLGHYKNKKFAKENPEAKWPAELNEN
                     VN"
     gene            complement(44218..45327)
                     /locus_tag="KR231_001323"
     CDS             complement(44218..45327)
                     /locus_tag="KR231_001323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HBH0003723.1"
                     /translation="MDFKSLGISENTINILKKSGITTPTPIQKESIKLIKEGKDVIAE
                     AQTGTGKTLAFLLPIFENISLDINDIQVLILSPTRELAIQITEEAMKLKESKDVSILA
                     AYGGKDIGSQIKKLKGNIHMIIATPGRLLDHLNRKTIDLSKLKTFVLDEADQMLLMGF
                     KNEVEAILKETSNKKQTLCFSATINSQVKKLAYRYTKNPVVVSIQKEEITLNNIKQEV
                     VETTDRKKLDALCKVLDEDNPFMAIIFCRTKRRVDNLEEALAIRGYNCQKLHSDIAQS
                     KRERIMKSFRNLDIQYLIATDVASRGLDISGVSHIYNYDLPETPEDYIHRIGRTGRAG
                     EEGYTCAFIDPKNERMLSEIETAIESKISRRIIEL"
     gene            45789..46982
                     /gene="nifV"
                     /locus_tag="KR231_001324"
     CDS             45789..46982
                     /gene="nifV"
                     /locus_tag="KR231_001324"
                     /EC_number="2.3.3.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homocitrate synthase"
                     /protein_id="HBH0003724.1"
                     /translation="MCVISKDRAKEIKIVDTTLRDGEQTAGVVFANREKIMIAEMLSD
                     LGVDQIEVGIPTMGGDEKNVIKHICSRNLKSDIMAWNRAVIKDVEESISCGVDAVAIS
                     ISVSDIHIENKLRTSRGWVLENMAKTVEFAKKNGLYVSVNGEDASRADIDFLTEFINV
                     GKQAGADRFRYCDTVGVMNPFSIKNAIETLYERTNFDIEMHTHNDFGMATANALAGIA
                     AGANYVGVTVNGLGERAGNAALEEVLMALKCVYKCDLNNIDTRKFRGICEYVAQASGR
                     ILPTWKPVVGDNMFIHESGIHADGALKDPHNYEPFDPSEVNLERKIVIGKHSGRAAVV
                     NKLSEYEMYISPENATKLLNAIRATSIRLKRSLMDKEILQLYCDILAHEKGTTEEEAV
                     RGSYI"
     gene            47007..48932
                     /locus_tag="KR231_001325"
     CDS             47007..48932
                     /locus_tag="KR231_001325"
                     /EC_number="4.2.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aconitate hydratase"
                     /protein_id="HBH0003725.1"
                     /translation="MGDNIVYKIIKKHIVDGEAVAGSSIGIKIDQTLTQDSTGTMTYL
                     QLEAMGIDKVKTKRSVAFVDHNMLQQGFENADDHKYIQTVADKYGVYFSKPGNGICHQ
                     VFLERFSTPGDTLLGSDSHTPTAGGVGMMAIGAGGLDVALAMAGGAYYIKAPKVCKVN
                     LVGKLNNMVSSKDIILEVLRKQTVKGGVGKVYEYGGEGVKSLSVPQRATITNMGAELG
                     ATTSIFPSDEKTLEFFKSQGREEAWIELKPDADAVYDEEITINLDELKPLAAKPHSPD
                     NVDEVENIGKIKIDQVAIGSCTNSSYEDLMKVAQILKGNKVHKDVSLVIAPGSRQVME
                     MIARNGALADIISAGARILENSCGPCIGMGQSPGTDSVSLRTFNRNFYGRSGTLSAQV
                     YLVSPEVAAVSAIKGVLTDPREFDIKFTNLDVNEFLIDDSMIIKPADVGSDVEVVRGP
                     NIKPFPLNTELSQSIGGKVILKTEDNITTDHIMPSNAKLLPFRSNIPYLANYCFNTVD
                     TEFPQRAKDNNGGFIVGGDNYGQGSSREHAALAPLYLGVKGVIVKSFARIHKANLINS
                     GIIPMEFCDEKDYENISLLDNLEIPNILDNLGSGILEVKNTTKGTSFKVKVELSAKEV
                     DVLKAGGKLNYTKNQAN"
     gene            48954..49949
                     /locus_tag="KR231_001326"
     CDS             48954..49949
                     /locus_tag="KR231_001326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isocitrate/isopropylmalate dehydrogenase family
                     protein"
                     /protein_id="HBH0003726.1"
                     /translation="MYKVTLIPGDGIGPEVAKAMKKVVEATGVEIEWEEVNAGEAVIE
                     EYGTPLPEYIIDSIKKNKIAIKGPITTPVGKGFRSVNVTLRQALDLYVNLRPIKSFKG
                     IKSRYEDVDLVVVRENTEDLYAGIEHKIGDYAAESIKIITRSASERIVDFACNYVKDN
                     KRKKVTAIHKANIMKMSDGLFLDVFREVASKHGVEYDDLIVDAAAMNLVLNPENYDVM
                     VMPNLYGDILSDLGAGLVGGLGIIPSANIGKDCAIFEAVHGSAPQIAGQNKANPTALI
                     QSSVMMLRYLGEYENAQKIETALEKVFLEGSKLTVDLGGSASTTEFADEVCKYIV"
     gene            50275..50748
                     /locus_tag="KR231_001327"
     CDS             50275..50748
                     /locus_tag="KR231_001327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HBH0003727.1"
                     /translation="MVVSVEVCLIKTLDSNILREVGTLSRAVNSINDIKYKELKLQKG
                     QFTFLTRICENPGINLVELSNMLKVDKATTTKAIQKLIKAGYVDKKQDKFDKRGYNLT
                     PTDKSLEVYELIIEEENRSIEICFDNFTDEEKQVVTKLLEKMSKNVENEWFKVKR"
     gene            50782..51276
                     /locus_tag="KR231_001328"
     CDS             50782..51276
                     /locus_tag="KR231_001328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBH0003728.1"
                     /translation="MIRKANMNDLESIMQIIKSTVEEMKTYNNTQWDENYPLEKDFVS
                     DIKKQDLYIYEVDGEVAGFICLNYEEPEEYLGLNWSSNKKAMVIHRMAVNPNFRKTGI
                     ASKLVDFAEKLAVENNVSYLKSDTYSINSKMNLLLTKCGFIKIGEMSFLGKEKSFYCY
                     DKIL"
     gene            51373..51894
                     /locus_tag="KR231_001329"
     CDS             51373..51894
                     /locus_tag="KR231_001329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HBH0003729.1"
                     /translation="MIGFLKKRRSIRKYKDVEVEKEKLDKILKAALLAPSSKGLRTWE
                     FIVVDDKEKLINLSQCRTKGGGFFLKNAPLAIVIIADKEKNDVWIEDASIAASYIQLQ
                     AHELGLGSCWIQVRNRMHDDNIEADKYIREELKVPSKYSVECIISIGYPDEEKKAYGD
                     SDLDYKKVHFNNF"
     gene            52083..52394
                     /locus_tag="KR231_001330"
     CDS             52083..52394
                     /locus_tag="KR231_001330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HBH0003730.1"
                     /translation="MGIFKTKMDEDWKVNYIKEFNEMRDSYESKLQKKQFEVDSLKSE
                     LDRLRSYKNSLKPKEKQITDDDINNIKSLRRDGLSYKEISNQTSWSKATVSRVLNGLY
                     D"
     gene            52422..53108
                     /locus_tag="KR231_001331"
     CDS             52422..53108
                     /locus_tag="KR231_001331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HBH0003731.1"
                     /translation="MKYSYKKCIIDSILLMFIVQILRMILNYVLLSQFEFTLENFNII
                     NLISFTLVGLSLILFLKDNSLYNKVRNRKITEAFEENKNNILIEKCKLILFVVVLSLA
                     IIVTYCTKGYVLFNVTMMTLSVLIVPIFEELFFREYIWNYLSNFIKSKSKIICITSIL
                     SGIYNIGYIDVIRNYVILYNNSSYTFEVIISKIMIGTVFGIVLGLVKYRFRDVGFCIL
                     LRSLFAIFIR"
BASE COUNT        19950 a         6149 c         9914 g        17201 t
ORIGIN      
        1 gtaatataca actactgcaa tctttgatac ctttatctgt atacttaaag tttccaccac
       61 agttttctcc taaagcatac aaaggacaat agcaaaatag acagttaaac tcttctggtt
      121 tattagtttt atgacaaggg aaaaattcgc aatctttgtg attaaaaaac ttataatttt
      181 cgcccatatt ttcctcctaa ttaaataaaa tttaaatttt ttatactata taagattttg
      241 gtgataatat aattatacta aataatttta tgaatagtcg ataatatagt attattaatc
      301 atagtattaa tggtataatt agtcaacaga aaaataatgt aaaaataatg taagtgtatt
      361 ttgtaattag aatatgtttt ataacaaaaa atgaggtgat taagtgaaag aaattcaaga
      421 aaaagcactt cttgtaggtc tgaatttgac tacaatagtg aaaaaaaatg atgatataga
      481 cactaatgaa tctatggaag aattaaaaga actaacaaaa gctgctgggg cagaagttgt
      541 aggtagctta attcaaaata aacactctgt agatgcagct tattatatag gaaaaggtaa
      601 agtagaagaa ataagagcct atagtgactc tttagatgct actttagtaa tttttaatga
      661 tgaattatct ggtgctcaaa tcagaaatat agagaatgtt gttggaagaa aagtaataga
      721 tagaactact ttaattttag atatatttgc tcaaagggca cttagcaaag aaggtaaatt
      781 acaagttgaa ttagcacaat taaagtatag attgccacga ctttatggaa tgggtggtga
      841 gatgagtaga acaggtgcag ggattggtac tagaggtcct ggagaacaaa aactagaaat
      901 agataagaga catatactta ataaagcagc agatataaga cgtgaactta aagaagtaaa
      961 aaagaataga gagacacaga gagttaagcg tttaaagtca aatataccga ttgtagcact
     1021 tgttgggtat acaaatgcag gaaaatctac cctgttgaac gaattaataa agacacacaa
     1081 ggattatgaa caagaaaaag aagtttttgt aaaagatatg ctttttgcaa ctttagatgt
     1141 aaccttgaga aaggctcttt tgccgaataa aaaagaattt ttagtagtag atactgttgg
     1201 atttgtaagt aaacttcccc atgatttagt agaagcgttt aaggcaacat tggaagaagt
     1261 acagtatgca gatttaatct tacatgtaat tgatgcaaca aatactagtt atgaattgca
     1321 aaaaagtacg actgaaggtg tattaaaaga acttggtgta aatgataaaa aacatatact
     1381 tgtatataat aaagtggaca agctagaatt ggatatatat cctaaaagtc aagaagatat
     1441 tgtgtatatt tctgcaaaac aaggcataaa tatggataag ttattaaata tgatagaaat
     1501 tgctttaatg gaaaatactt attcagtaag tttgatgtta ccttatgaga gaggtgatat
     1561 atttagtaga ataaaagata aatataatgt ggagaatttt gagtatgggg aaagtggtat
     1621 aacgctagat gtagatttag atgaagaaga ttttaatatc tatagagagt acatactaga
     1681 aaaataggtt gaatatggat ataaactggg aaaatataga taatcttgaa gattatttta
     1741 taacctatct tctttataaa gaatctaaaa cagtatctca aattagtaaa attagaaata
     1801 tttcaagtac tgaagcaagt gagcaactta tacaagcaaa gttaaaaata aaggaaatgc
     1861 aaaaagatga ttttgaggca tctaaggata ttttggataa atttctagaa ctagataaaa
     1921 ttaagagact tgattttatg gatagcttag atgacgaaaa aatggtatac tttaagagaa
     1981 aggttttcaa aagaatcctt gtagaaaaaa atgctgaaga tttaattgtt ttaatttggg
     2041 cgacaggtga gctaaaagat gataggtttt tgaaattgct tcatcagctc acaaaccaca
     2101 gacactcaga tattagaaga ataacttatt cagcaatcag aaagattgaa tcaccaagta
     2161 gtagagaagt actgcaaaaa ggtctctacg acaaaaatgc acagactagg cagtactgtg
     2221 caaaagctct ttcaaaattg ggagatgaaa acagtttaaa gattttacag cagttgaaag
     2281 acaagaataa gaattttgaa aaagaatatg tgcttagagc ttatgacaaa gccattaagt
     2341 cattggaaaa tgcaaaaaat ttgaaaaagt aattttttat taaagcaatt tgtttactta
     2401 atgatgtatt tctaaagttt aacaaggtaa taaataaatt aatgggaggg gtttcaaatg
     2461 atagtaagac gttgtgcagg tggagtagtg ttttatgcta ataaagtact tattgtaaaa
     2521 aatgataggg gtgaatggac acttccaaaa ggaaagatac taggaggggg acttccatat
     2581 gagagtgctg ttcaaagagt taaagtagaa actggcatag atgctaaaat gatagatgtg
     2641 gctggcgata ctatgtatga atttttctca agaagtagac aacaagaagt ttgtaatgca
     2701 ataatgtggt atgttatgga agcttgtaac actgattgtg tacttgctcc tgaatttcaa
     2761 gaaggtggat tttataaagt aaaggatgct ttagaaatgt tatcacatca taaagagcaa
     2821 gctttagtag aagtatctta taaaaagttt aaggaattaa agaaattagt ttcagagggc
     2881 gatgatgttc cagcaaatta attgtgaatt tagaggattc tgaggaaggg atagcccctt
     2941 ccttttttaa ttgaagcagt tttaagcgta aattatatag tctctttaaa ctatgattta
     3001 tcaatttaga gatttagtag tttatattta aaatcagtaa gatatattta aaataaaaat
     3061 taaaaagtat acaattttat tatataattg tcttatgatg ttgattaaag aattattaaa
     3121 agtccattta tttttaaata gaataatttt ataaatatat atttgatgtg tatattagaa
     3181 aatgattaaa ataggaggaa atacaatgag caattacagg acattacatg aatttggaat
     3241 ggatgaaata acgattgaaa agtctgtttt tattggatat gctaagccta taaagagtga
     3301 agaagaagca ttagagttta taaatgaaat aaagaaaaag cataaagatg caactcacaa
     3361 tgtgtgggct tatactgtag gtaaaaatat gaatatacaa agatatagtg atgatggaga
     3421 accacaagga acagctggga tacctacatt agaggttata aaaaaagaag atttgagaga
     3481 tgtagcggtt gttgttacta ggtattttgg aggaacaaaa ttaggtgcag gtggtctagt
     3541 tagagcttat acaaaaggtg ctaaactggg acttgaagca ggtaagataa tttataaggt
     3601 aatgtatcaa gaagttaagg ttaagataga ttatactcaa cttggaaaag tgcaaaatga
     3661 gttaatgaat ttggggtatt ttataaaaga tactgtatat gaggataatg ttgaaatagt
     3721 agtatattca agattagaag atgtagagaa attatcagaa aaaatgattg atataacaag
     3781 tggaacagga aaaatagttt taggagagga attttatttg tctgaacaaa atggagaaat
     3841 tttaatataa tctaaaaggt tattagaata gttaatacct caaatagcca attagtattt
     3901 ttaagtgaaa agccattaaa ttgatttaat ctaaatcaat ttaatggctt tttatcggat
     3961 tttgcacaga atcctttttt tacttcaaat aaaccgacta aaagtaaaaa tatcccaaat
     4021 atttttttta atatatctga agacagataa ttagctaata gtgaaccaaa tacagctcct
     4081 aaaaccccaa acacagctat aggtataacc aatttaaaaa ttacattttt attttttata
     4141 tgtatagcaa gtgctataag tgtcataggg atagatgaaa gtaaatttac gctttgtgct
     4201 attttagtgt ctatgccagc aagtaaaacg agtgcaggta taaggattgt tcctccaccc
     4261 attcccattc ctccaataat tcctgcaaaa aatccaatta gagcaaataa cattaaaaca
     4321 ccatccttaa tgctgcaatt atcataatta ttccaaaaga aattctaaga aactttccag
     4381 taaccttatt tagtaattta gctcctataa taccaccaag aatacttcca actgcaactt
     4441 taattgttaa gttaacatca taagtacctt tagatacata taaaacagaa cttgctgtcg
     4501 ttaagaatat tattatagaa agagcagttg catgagattt atgttcttct accttaacga
     4561 tgtcatttaa tattggaact aaaagagtac ctcctccaga accaaaaact ccatttataa
     4621 atcctgtaaa aactccaatt atcgtatttt ttaagttaaa atcaaagtat tttttcttta
     4681 aatcatcagt ttttttcata aaaatcacct tctgaaatag ttttaccaaa ataggcaaat
     4741 tatatttata taaaataaga ttaaatataa tctttcatgt ttgtttaatt ttgcataaaa
     4801 aaaaacatat taaaacaaca tattaatata tggtataata tattaaaaca aagtagcaaa
     4861 tttgagagga gataacaatg tcaaatataa aaatacaaat agacaaaact gtagaatggc
     4921 ttataaataa ggttaatgag gcaaatgcaa aaggattaat tgttggtgta tctggaggaa
     4981 ttgattcggc agtagttgct aatttaatta aaaaggcatt tccagaaaac tctatgggag
     5041 ttataatgag cataaaaagt aatcctcaag atagagaaga tgcacttaag gttatagagg
     5101 gatgtgatat agaatacctt gatttagacc ttatagaacc acaaagtgct atattagaca
     5161 tggtagtagg aaatttaaaa gataaacatt tatatagaga agaatattta aagatgacag
     5221 atgcaaactt aagagcaaga gtaagaatga gtacaattta tacaattgct aacaatctag
     5281 gatatctggt tgttggtaca gacaatgctg cagaaataca cacaggatat tttactaaat
     5341 ttggtgatgg tggagttgat attttaccta ttgcaaattt aactaaagga gaggtgtatg
     5401 aatgggcaaa agagcttggt gttcatgaag atttaataaa caaagctcct tcagcaggtc
     5461 tttgggaagg tcaaacagat gaagatgaaa tgggaactac ttacaatatg atagatgctg
     5521 tgttagaagg tagattggat gaagttccta aaagagacca agagataatt gaaagacttc
     5581 atagattaag tgaacacaag agaaaaacgc ctgcacaacc tcctaagttc taatttacta
     5641 tttataagat ttgtgataaa atttacaagt gatgaaaatt agaataatta attgtacgta
     5701 ttaaggagtg gaaatatggg acgtataggt aatataatta atagaaaagg taaacaagat
     5761 gctcaaagag caaagatatt tactaaacat gctagagcaa tagcagttgc agctaaggaa
     5821 ggtggagcag acccagagta caatgcagcg ttaaaaacag ctatagaaaa agctaaggca
     5881 gataatatgc caaatgataa tatagataga gctatcgcta aaggtgctgg agcaggtgct
     5941 ggagaagact atgaaactat agtttatgaa ggatatggac ctggtggagt tgctgttata
     6001 gtagaaactt taactgacaa caaaaacaga actgctggta acgtaagata ctattttgac
     6061 aaaaacggag gaaacttagg aactagtgga tgtgtgtctt ttatgtttga taaaaaagga
     6121 caaatattag ttggtttagg agatggagtt tcagaagaag aattgatgga tgttgcatta
     6181 gaagcaggag ctgaagattt cataacagaa gaagatggtt atgaaataat aactacacca
     6241 gaagattttt ctagtgttcg tgatgagtta aaagctaaag gatatgagtt tatatctgct
     6301 gatgtgaaga tgatacctca aactacaact gtattgactg aagaatctca tttaaaaatg
     6361 atgaataaat tagttgatat gcttgaagaa gatgatgatg ttcaagatat atatcataac
     6421 tgggaagtag aataaatagt ataagcatat tgaaatttat aagtattgaa tcaattttaa
     6481 catgtgataa attttataga ataagaaaca ctaaaataga catacgcacc tctaacctat
     6541 atttgcataa taatatgtaa gcataggtaa ggggtgtttt tatatttata ggttaagaaa
     6601 tttaaagtaa attttgagct ggactcgatt gtctataaat aattgatggg tatataactt
     6661 gttgctgaat accatttata cgcccagtta ctgtatcaat aatcatccta agactacgtt
     6721 ctgctgtctc ttccattttt aaatctataa ctgtcaaagg aggaatactt cttgccatta
     6781 gtcgtgaagg tccattactt gctgcaaata tttgaatatc ctctccaatt acaattcccg
     6841 attcatgaaa tgcattcatc ataccaagag ctaccacatc atgattacaa aaaattactt
     6901 tttttagtga attttttgca agcatttttt gagcaatatc atatccacta tctattttat
     6961 tagaacaata atatatagaa tctgatagat gtattccatg ttctttacat gtttttaaaa
     7021 aagatttacc ccttaaagtc atacatgtaa aggaagttgg gttgaataca acagcaatat
     7081 catttttacc attttgaata gcatgtaaag ctgctatacg accagtttcc tcattatcaa
     7141 tagatacact tgaaaaacca ggtatttcac gatttacaac aactacagga attttaggtt
     7201 tattttttac tagatattct atatcatcag cattgatacc tgttaaaaca attccatcat
     7261 aataattatt tgcaaaaaag tattcatcat cacatagatg accaactttg taaggtcgta
     7321 tgatgatatt tatgtttaaa tgttctaaag aaattatgtg gtttattgct tgaagtatat
     7381 tggttgatgc caactcaaat ccctcatcct gccaataaaa agctatttta atattattat
     7441 gtttaatagg agtagagcgt ttatatccaa gcttatcagc tgaatttaat ataagctctt
     7501 gtgtatgtag cggaatcctg cgttcatttc ctttaccact taagacgtac gagacagttg
     7561 ctgaagaaag accacagtct tttgcaatat ctttgattgt tgccatgata aaatcctcct
     7621 taaatagttg cttaaatttg cttataccaa taatcttaac atatattcaa ctaaagaaca
     7681 atattctaca aggtgcatat tttacagaat tagaataaat aaatttaaaa aaacttctta
     7741 cttatgttga cataatttag tttataggat tataatatgc ttaaataagc ttattattaa
     7801 cttaaattaa gcaaagttaa gcaggaacat gcaatgctag cttgcaatgt gactgtaaag
     7861 ggggaaaagg tatgagtaag gtaaatatat ttgaagttgg tcctagagat ggatttcaaa
     7921 acctgaaaga gtttttagaa actgataaaa agcttaagat tattgatggt cttattgctt
     7981 cagggattaa acaacttgaa attagttcat ttgtaagccc aaaagcaata cctcagatga
     8041 aagatgcaaa agaagtagca acttattgtg tagaaaaata tcctgatgtg aaactttatg
     8101 cattagttcc aaatttatac ggtgctaaag ttgcatggga gtgtggtata agagatatat
     8161 cctatgttat atctttgagt gaaactcata ataaaaaaaa tataaatcgt acccatgaag
     8221 agtctattga tgagcttaaa aaaataatga atacttatcc agacatgaat atatgtattg
     8281 gaatggctac tgtatttgga tgtccttttg aaggtttacc aaaaattgaa gatgccataa
     8341 gatttgctaa acgcctttgg gaaaacggta tcagggagat gaatctagca gatacaatag
     8401 ggattgctga ccctaagcaa gtaagagaaa ctattagtgc attagttgaa gctttaccag
     8461 agtgcagatg gcaggtacat attcatgata ctagaaatat gggaatggtt aatactcttg
     8521 tggctattga atctggaatt actactgttc agtctacact tggaggatta ggaggatgcc
     8581 catttgctcc tggagcatct ggcaatactg caactgaaga tttagtatat atgcttgaac
     8641 gtatggggta tgatacagga gttgattttg ttaaacttct tgaattatca aagtatcaga
     8701 agagttttgt aaatggagta tatagtggtc atcatgtaaa tataaagtct gatagttgta
     8761 attgttagtt ctattgatta atcgattaaa aaaatatgtt gattaaaaaa atatgctgat
     8821 tggtaaaata gatttattga taaaaaatat aaattataaa atacattatc taataaaaca
     8881 aataaaaaaa ttgaggggga ttagtatgga tattatagct ttacttttat ttttaggagt
     8941 tattattatt gcatttgtac gtaagaataa tgcaggtatt ttggctctag ctattggtgt
     9001 catagctgtt agaatttttg gaatggatga taaagaactt tatggagcta taagcaactc
     9061 aatgtttact acacttgttg gtataacact actctttgca atagtgaact caacaggagc
     9121 attaaagctt gttgcagaaa aaattgtagc tgcttctggt aaacgtgttt ggcttatacc
     9181 tatagcagtt tttatagcag gatttgttgt tgctggtgtt ggacctgggg caattccagc
     9241 acttgcaatt atcccagcaa tggctgttcc tgtagccata acggttggtt ataatcctgt
     9301 aatgcttgca cttataggtg aatgtggatt aatggcaggt cgtatgactc ctattactcc
     9361 agaaggtcaa attataacaa ccgttgcaga aggggttgga attgaaaatg ttatgcctac
     9421 tatcttagcc tgtcaaactc tttctacaat tgtattttca atagtattgt ttataatttt
     9481 caaaggatat aaacttaaaa aacctataaa tgttatagat agtaagcaaa tagaaaaatt
     9541 caatataaag cagataattt ctctaataag catagtagtt atgattgctt ttatcataat
     9601 ttttgatatg aatgttgggc ttgcagcttt tgcagtttca gctgtactta tttttttcaa
     9661 tattgctgat gaaggagaat gtatcaaatc aattccatgg agcacgatag taatggttct
     9721 tggagtaggt gcaatgatga caatcgtaga tgcagcagga ggtattgact tgatgagtaa
     9781 tgcattatca tcactgatga atagtaaaac agctactcca attatgagta tttcagcagg
     9841 acttatgtct atggttagtt ctgctttagc agtagtttat ccaactatga tgcctatgtg
     9901 tgttgatata gctaaggcag ttggaggagt agacccacta gcacttattg ctgcagttgg
     9961 tgttggaggt tctcttgctg gtgtaagccc actttctact ggtggggcat tgattttagc
    10021 agctatgggt tcaagtaaga aagactttaa taaggaagaa caaaataagg tttttgtaca
    10081 gcttttcatt atgagtgcag ttggcttatt ggttattgca gtagtatcaa tattatcatt
    10141 taatgcaata acacatttaa tgaactaatt agaataactg aaaataaatc attaaattta
    10201 acttttaata ttaatcaata taatataatt tggaggggaa gttatgaaaa aaggagcatt
    10261 aagcaatata aaggtacttg accttacaag agttcttgca ggtccatatt gtacaatgat
    10321 gttggcggat tttggagctg atgttataaa aatagagatg ccaagaaaag gtgatgatac
    10381 aagaggtttt ggaccttttg taaatggaga gagtttatac tatgcaaata taaatagaaa
    10441 taaaaaaggt atcactctaa accttaaatc agaagaagga aaaaatatat ttttagaaat
    10501 ggtaaaacat gctgatgttg tagtagaaaa ttacagacca ggtgtaatgg aaaagttagg
    10561 tctgggttat gatgagttgg ctaaagttaa caatcaaata atttatggag ctgtatcagg
    10621 atttggatgt tatggaccat attcagaacg tccaggttat gatattattg cacaggcaat
    10681 gggtggtctt atgagtataa cagggcaaga aggaggagaa ccaacgagag ttggtaatgc
    10741 tatgggtgat gtactaggtg gaatgaattt aactattggt atactcacag cactcaacgc
    10801 tagaaaaata ataggaaaag gacaaagagt agatgtttcc ctcgttgatt ctgttgtatc
    10861 gtctctcgaa actggtatac agagatactt tgattcagga caacctgaac ttatgggtaa
    10921 tagatatgct tcagcctatc cttatgactc ttttaaggca agtgatggaa gttttgtaat
    10981 aggctgtggt aatgacaaac tttttgaaaa gttatgtaaa aaagttcttt ttagagaaga
    11041 ccttttaata gatgagagat ttaaaacaaa tcttaatcgt tgtgaacatt acaaggctct
    11101 taaaccagaa atagaaaaat ggtctattaa gcatacaata aaagaagcag ttgacttaat
    11161 atcagaggct ggagttcctg ctgctcctat ctataatctt gattgtgtta caacagatga
    11221 acatatagca aaagcaagag aaatgattgt agatattagt catcctatta taggaaatat
    11281 gaaagtcaat ggaaatccag ttaagttgat gacaacaaaa gctaaaattg atatgccagc
    11341 accatctcta ggggaaagta acgaggagat ttataatggt tggcttggtt ttgatagtga
    11401 taaaataaaa gatttaaaag aaaatggagt tatttgatta aaaaatagct aaacacactt
    11461 gtgactttag tcaggggagg ttcagttaga ataatatcaa aaaatattaa atcaatactg
    11521 taaatcaaat atagaattgt cagaagcatt taagatggga aaagctactt agacattgag
    11581 tctttgtggc ttttcctatt ttcattaaga attttatatt atcagaatag atatgtacta
    11641 aactaaagta ttaacaattt aaattaatag aaaataaact acctaattat gttgaataaa
    11701 gactacttta gtgaaaataa acttatagag atgctattta aattatttta atggaaatat
    11761 caaaaatgag actgcattct caaaaatgag actgcgtttt ttaagtattt tctcgaaaat
    11821 gagacaaaaa tattgtttta tgggttttat tgaagaaaaa ttcttctgtg aattacaatt
    11881 taatcaattt taaagttgaa aattattaaa aatttagtga aatttatgta tatttcgttt
    11941 attttattaa aaataacaat tttttactaa aaataaagaa cttcaatggt gattggcata
    12001 gtacttgcta ttttatatta acaagaaatg tagaaaaaat aacaatgtat aatgggggga
    12061 atatgatgga atctgtaatg gaaaatttga acaatcttaa ggtggaggtt aaggacaaag
    12121 tctgtgttat tactataaat agacctaaag ctttaaatgc tcttaatagt gacactctta
    12181 gggaactatc acaagttatt gatgtagtat cagaaaatga ggcaatatta ggagttatta
    12241 ttactggaga aggtaaagtt tttgtagccg gtgctgatat acgccagatg caaaactata
    12301 aaagtgagga aggcagaaaa tatgcaggtt atgctcaggg agtttttgat aaaattgaag
    12361 ctcttgaaaa aacagtaata gcagcagtta atggatatgc attaggtggt ggatgtgaac
    12421 ttgctatgag ttgtgatatt agaattgcat cagaaaaggc tatatttgga caacctgaag
    12481 ttaatttagg agttattcca tgttttggtg gaactcaaag attatcaaga cttgttggaa
    12541 ctggaatagc taaagagtta atttttacag ggagacaagt aaatgcagaa gaagctaaat
    12601 ctattgggct tattaataaa gtggttccaa gtgatttact tttagaagag tctatgaaga
    12661 tgatgaacca aatagttgaa aaagcgccaa tagcaataag atatgcaaaa gttgttatta
    12721 acaaagggat agatatggat ttaaagaatg ctcttgaact agagaaagat attgcaggtt
    12781 taacttttgc tacaagagat aagcaagaag gaatgaatgc atttatagaa aagagaaagc
    12841 cagtttttga aaataagtag ctattataac taaaattgga acaatgtaga atatattcaa
    12901 aatctaaatt tcgtgaaaaa atacatatag tttaatttta aaaggagtta atttatgaat
    12961 acgggagtaa ttataagttt agtagggatt atcatagctc tatctcttct agttgtaatg
    13021 gttatgaagg gaataaatat ttttattata gcaattgtat gttcatcatt agttgctata
    13081 acaggaagcc taaatgtgta tgatgcactt aaagtggatt atatgacagg gtttgttgga
    13141 tttcttcagg caaatttctt tattttccta acagggacat taatgggaaa aataatggag
    13201 attactggtg gagcaaaatc tattgctaag atgattgtaa gatggattgg gaaggataaa
    13261 gcactacttt ctattccaat agcttgtgga atattagcct atggtggagt aagtgttttc
    13321 gttgtaagtt ttgcagtgtt tccgatagct ttagaaattt ttaaagaagc tgatttgcca
    13381 cgaagattta taccagcagc tttgactttt ggatgctcaa cttttgctat ggttgcacca
    13441 ggggcaccac aaattcagaa tattgttcca gcatcaacat tagggacaga tattatggct
    13501 ggagcagtaa atggttttat atcatgtgca gtaatgttta tagttggaag tacaattttg
    13561 tacaaaatgg tttcaaaaga aaaagccaat ggtggtcatt ttatagcaca tgaatcagat
    13621 atatttgatg aagcagaagc aactaattct aagagagaaa atggtcccaa tggtgtaatt
    13681 gccttaattc cattgatagt gtcaatttta ataattaatg taaaagttaa tggaaaagcg
    13741 atagtaccaa ttgaggtggg agtatttatt ggagctttat tagtatattt attgttaaat
    13801 aaatatcaag ataatactaa aatagttgga catgttggtg atgcatgtaa aactacagta
    13861 gtagcaatat gtaatacttg tgctgtagtt gcatttggtt cagtagtaaa atcagcagtt
    13921 ggttttgact tcatagttaa tgctatgact aatattcctg gtcctcctat tgcaggggct
    13981 gcagttggaa ctacagttat tgcaggtatt tgtgggtcag cttcaggtgg actaggaatt
    14041 gcagctccac ttcttggacc agtattttta gccaagggtg tttccgctgc agcattaact
    14101 aggactatgg caatttcatc agcagcatta gattcacttc cacacaatgg atatattgtt
    14161 actgtaacaa atggtctttg taaagaaaca cataaggatg cctatatgcc aatattctgg
    14221 gtaactgttt taaccccatt tattggaacc atagtagcag tcctactgtt tacaatgttc
    14281 ccgggattgc cataagagaa aagataaaag gtataaatta tattttgatg ttataaaatc
    14341 aattttcaaa atatatacaa taaatttcat gttttaatac tgtaaatatg tatttaaaat
    14401 aacaaattga ccatataagg aggaattgaa agtgttaaat aaaccattag agggagttaa
    14461 ggttattgac ctaacgtatt ttgtagcagg tccagggact tctaaaatat tagctgactg
    14521 gggtgctgac gttattaagg tagagccaag ctttggagac ccaggaagaa agacaggggc
    14581 aacaatgaca atgccaatag atgattataa taatcctttt tacagcacat ataattcaaa
    14641 taaaagaggt ttgtctataa atcttaagag tgaaactgga attgaaatta tggataagct
    14701 tttaagcgaa gcaaacgtat ttgtttcaag ttatagaaca ggagcattaa aaagactagg
    14761 tcttgattat gaatcattaa gtaaaaagca tccacacctt atctggggtc agataaatgg
    14821 ttttggcgat tttggacctg ctaaggataa tgcaggattt gatacagttg ccttttgggc
    14881 aagaagtggg gctatgcttg atatagcaga aaaagataca agtccaataa atccacctat
    14941 agcctttgga gatgcaacaa cttcttgtag tttatctgga ggaatatgtg cagctttgta
    15001 ccagcaagct aagactggaa aaggacaaaa agtaatggca tctttatttg ggcaagcaat
    15061 atggaatgca tcatctttat tagcatctac acagtttagt gatgagtatc caaaaactag
    15121 aaaaaatgct atttcaccag taataaattc ttatcgttgt aaggatggaa agtggatatt
    15181 cttaagtatt ttagagcatg aaagatattt tgaggcactt tgtagattat ttggaagaga
    15241 agacttaata aaagaagaga aatttgcatc ttcagtagaa agtaagaaaa atgctacaga
    15301 acttattaat attttagatg gtgaatttgc aaagtttact caaaatgaga tggttgaaaa
    15361 acttactgct gctgatatag ctcatgaaaa aattcaacat gttaatgatg tagtgactga
    15421 tgaacaggct attgctaata actatatata tgaacataca agtaaagatg gaaataagac
    15481 aatgcttgca tctactccag ttaaatttgg aaatattgaa gttaacatga cttgtgatgc
    15541 tccacttata ggagaacatt cagatgagat attgagagaa cttggataca gtgattctga
    15601 tatagaggct ctaattgaat ctggaattgt aacaatgaat aaagaagcat gtgaaatatg
    15661 ttaataaaca tgtgaagtat gttaataaat aggagggaat tttatggatt ttagattaac
    15721 agaagcacaa ttaatgcttc aaagagtagc aaaagaattt gcagagaatg aaatagcacc
    15781 aatagctgct gaaacagata aaacaggtat ttttccaagg gagcttttta gcaaaatggc
    15841 taaaatagga tttaatggaa ttggaacacc tgtagagtat agtggttctg gtggggcaga
    15901 tatagaaaag gtaattgttg ttactgagat tgccaaaaaa tgtgcagcat ctgcagcaat
    15961 attatcaata cacacaatat atgctcaagc tattttgaaa tttggtactg aggaacaaaa
    16021 gaaaaaatac cttccaatga tggctgaagg tgggtgtgta ggtgcttttg ccttaaccga
    16081 acctaatgct ggttcagatg ctgcgagagc tgcaacaact gcaattattg atgaagaaac
    16141 tgatgaatat gttttaaatg gaactaagtg ttttatttct ggtggaggtc aagcagaatc
    16201 attaataata tttgcattga cagacccatc aaagggaata aagggaatgt ctgctatcat
    16261 tgtcgacaaa ggtacgccag gtttttcaat aggaaaaatt gaagaaaaaa tgggtattca
    16321 tggttcagaa actgcagagt taatatttga taactgtaga gttccaaagt ctaacttatt
    16381 aggaaaagaa ggtaaaggat ttaatatagc tatgacttgt ttagatggag caagaattgg
    16441 agttggagct caagctgtag gaattgctga aggggcttta gaagaaagta tcaaatattc
    16501 taaagaaaga gtccagtttg gcaagccaat ttcagctttg caaggtattc aatggtatat
    16561 agcagatatg gcgacaatgg tggaatcagc aaaattatta gtatattatg ctgcagattt
    16621 gaaagctaga ggagaaaaac acactaaaga agctgctatg gcaaaataca atgcgtcacg
    16681 tactgcaaga gaggttacaa atttagccct tcaaatccat ggtggatatg gatatatgaa
    16741 ggattatcca ttagagagaa tgtacagaga tgccaaaata acagaaattt acgaaggtac
    16801 ttcagaaata cacaaagttg ttatttcaag agcagtacta ggataggagg aaaagaatga
    16861 atatagttgt ttgcttaaag caagttccag atactaatga agttaaaata aataaagaga
    16921 caggtactct aataagagat ggtgtaccaa gtataatcaa tccagatgat agaaatgctt
    16981 tagaagaagc tctaaaaatg aaagatgaac taggagcagt gattaaggtt ataagcatgg
    17041 gacctcctca agctaaaagt gctttaaaag aagctttggc aatgggagct gatgaagctt
    17101 atttaatctc agatagagct tttggtggtt cagatacttg ggctacatct acaattattg
    17161 ctgctgctat agagaaggtt ggaaagtatg atgtaatatt ctgcggaaga caagctatag
    17221 atggagatac agctcaggtt ggaccagagg ttgcagaatt tttagggata ccacaagtta
    17281 cttatgcgaa agaagtaaag gttcaagatg acaaattact agtaactcgt tatacagaga
    17341 caggggatta tttaatagaa gcaaagatgc cagttttatt aactgctata aaagagttaa
    17401 acaatccaag atatccaagt gtcaagggaa tcttagaagc ttataataat ggagatgcaa
    17461 agattactgt attaacactt gcagatttag atgttgatac aactcaaatt ggattaaagg
    17521 gttcacctac aaacgtttat aagtcttttg taccagttaa agacaagcat aatgaaataa
    17581 tagaaggtat aaataaaaaa gaaaaagctg agaaactaat agaaatacta ttcgatttga
    17641 aactagtata ggagtgttaa gatgatgaga gcaaaagtta atcaaggtat aaatttaaat
    17701 gattataatg gtgtttgggt aataggagag caaagggaag gtaaaattaa tcctgttacg
    17761 atagaactta ttggtgaagg aagaaagctt gctgaccaat taggaaaaga gcttgcagtt
    17821 gtgatagctg gatatgaagt agagaaagaa gtgaaggaat tacttcacta tagtgttgat
    17881 aaagtatatt acatcaatga ccctcttctt aaagatttca ctactgatgg atatgcaatt
    17941 tcaattgcaa atttaatcga aagaaaaaag ccagaggttg tattggttgg tgctacttct
    18001 ataggaagag atatagcgcc tagaattgca ggtaaggttg gaacaggtct aactgctgac
    18061 tgtacaaaac ttgaaataga ttcaacagat aataagttat tacaaacaag accagcattt
    18121 ggtggaaatt taatggccac tattgtttgt ccaaaaaata gaccacagat gtcaacagtt
    18181 cgtccaggag ttatggcaaa agctgtaaga aacgaatcag agactggaat tttagaagtt
    18241 gttactccag aacttactga aaaaatgatt agaactagat tagtagagat acttccacaa
    18301 gaaaagaaat ctgtaaatct aactgatgct agaataatag tatcaggagg aagaggatta
    18361 aaaagagcag aaggatttga gcttataaaa gaattggctg ataaattggg ggcagagatt
    18421 ggtgcttcaa gagcagcagt agattcaggg tggatagaac attctcatca agtgggacaa
    18481 acaggaacta ctgttagacc agaactatac attgcatgtg gaatatctgg agcaatacaa
    18541 catttagcag gtatgagtga ttctaaatat atagttgcta taaataaaga tgcaaaagcc
    18601 cctattttta gtatatgtga ctatggaata gtaggagatt tatatgaaat tatacctgaa
    18661 atgatagaat cattaaatag gtaactttta gaaaacattg aatatgtaga atgataagtc
    18721 ttataatatt gtattgtaag acttattatt tttgctgaag gttatagtgg ggagatgaaa
    18781 caatgaaaga gcagtggtat aaggatatat ttgcaagagt attatctatg actgatgatg
    18841 gttttattgt tgtaaataga agtggagtaa taatagatat taatgataaa tattgtgact
    18901 ttttaggaaa agaaagaaaa gatataatag gacaaaatat acaaagtatt ataccaaata
    18961 caaaaatgct agatgttatg aaaaataagt attgtgaaga aggagctata catcattatt
    19021 caggtggaaa tacaaaagaa aaaagtgtaa tagtaagtag gtcttatgtg gaaaatgaca
    19081 atggagaagt agttgcagga gtagctcaag ttaaatttag attgcaatca tttgatgtag
    19141 ctaaaaagtt aatgtcagaa tatatggagc tccaatatta taaagagcag tttaaggata
    19201 actgtggttt tgacaagctc ataggtgaaa atagagactt catagaactt aagaaaacag
    19261 gtgtgaaagc ttctaaaaca aactttccag tacttttaac gggtgaaaca ggtacaggaa
    19321 aagaagtctt tgctagagca attcacaata atagcagtag gtcagataaa cctatggtta
    19381 gtataaactg cgctgcaata ccagaagaat tattagagtc agagctattt ggctatgacg
    19441 aaggagcttt tacaggagca aaaaagggtg gtaaaaaagg taaattttta gttgcgaata
    19501 atggtacaat ctttttagac gagataggtg acatgccttt gaccatgcaa gcaaaacttt
    19561 taagagttct tcaggaaagt gagatagaac cagtgggagg tcttaaaact ataaagatag
    19621 atgtaagagt aatctctgcc acaagaaaga atttaagtaa aatggttgaa gagggattat
    19681 ttagagaaga cctatactat agattaaatg taataaacat tcatatgatg gaattgaagg
    19741 acaggcaaga tgatatttta ttgctagcaa attatatatt aaacaaatta aatgttgaat
    19801 acaaggaatt gaaggtttta agtgataagg ttaaaaattg ttttattaac tatacttggc
    19861 cgggaaatat aagagaacta caaaatgtaa taaaaagtgc ctatgctgta agtgatgata
    19921 tggtcattat gatgtgtgac cttccatcta agatggataa tatcagcaga gtagctcaat
    19981 gtaatgtgga tagcaattgt tcaattcatg aaatggttga gaattatgaa aagagcttaa
    20041 ttattgatgt gttaaggaag tataattgga aatgttctaa ggcagcagag gttatgggaa
    20101 tacacaagag tcttttatat aagaaaataa aaaagtatga aattgaatta aataattaag
    20161 ataaattgaa ttaaggcaat gctaaaaaaa cgcccttatt caaagcgaac tgtataaact
    20221 gttttatgca gttaaaacgt gtaaaagtag atgtgaagta ctaatgtcaa tcattagtac
    20281 ttttttatta tatttataat tactatctat atttcagtat cttttgatat ctaagattat
    20341 tatgtttaat ttaggatata acaaaaccct cttagttatg gacagttttt tatattttaa
    20401 ctgtctacta agaggggata gtttagttta aatttagagt aaattttatc tagcatttat
    20461 aaaaaatatt ttgaatagct tttttgttat ttaatcataa ttttctactt ctttatcaag
    20521 ttctttgcca caagaatcac acttatatat agcattgtat ccgtaatcat attcatcaac
    20581 tattttcttt tgtctaaata caccaccaca ctcacatagg aaaccaattt ttataagtgt
    20641 aacgataaat tgtgatttta taaattttat atcattacat ttatcgttag tgtaaaatgt
    20701 ataaatataa gagttatcgc actcatctct taattcaaat ctttcaatat atgtgttatt
    20761 ttttaattcc tcaaattctt ctttagttaa atatgatttt tgttgcaatt catgtaaacg
    20821 cttaatttgg tccattattt atatcctccc aataatttta gtattttaag cttagataag
    20881 gaatctaagt tttattaaat ttatcccaag gaattattta aatcatattt agttttatta
    20941 attacaacat atataaatta cacgaaaata aaactaattg taaaaataat atcctgtgaa
    21001 aacctaaact actaacccct tactaacccg aaaactaaaa aaagaaaata tatccaaata
    21061 taagtgatat ataaataaag atgtttcata taaatttaac tttaaatatt ctgacaataa
    21121 tatatataaa tatattatag ttaaaatata ccacatattt tgggtattgt atactggaat
    21181 tagagtaatt aatttatttt ttaacataca aatgatttta tgaaaaaaaa caagactcaa
    21241 aaatttttat attctttgat agaataaaat tgagagtaaa tttattgaat tttataaaat
    21301 ttataagggg tgagtctaag atatgcatga agataaaaat gatatatttg aatcaataga
    21361 tactgaggat tttgataata aaacagaaga agaatgttta gagctagtaa gaaaaaatgg
    21421 attgaattta atatacataa aaaatcaaac agaagagata tgtctagagg ctgttagaca
    21481 aaattgtaat gcaataaaat gtgttcagaa tcagacagaa aaaatatgta tagaagcagt
    21541 taaacaagat tggagaatgt tagaatttgt agaagagcca acagaagaaa tttgcatgtt
    21601 ggctattaac caagatggaa cagcattaaa atatatagaa aatcagacag aggagttatg
    21661 cttaagagcc gttgaaaaaa atggtgcagc tttggagtat gtaaaagaac aaacagaaga
    21721 aatatgtata gaagcagtta gaaacagcga atttggattg gcaagagtga aaaatcaaac
    21781 agaaaaaata tgtatggaag cagttaagca ttgtagctat aatctaaaat gggtagaaaa
    21841 tcaaacagaa gaaatatgta tggaagcagt gagacaaaat gggcttgatt tgaaatttgt
    21901 aaaaaatcaa acagaaacaa tctgtttaag agcagtaaga caaaatggaa tggcattaga
    21961 atttgtaaag gaacagactg ttggtatatg cttaaaggca gtaagacaat atggaatggc
    22021 attaaaattt gtaaaagaac aaacagaaga aatttgtaca gaagctataa aacaagataa
    22081 aagagcactt agttttgtaa aaggagataa ggaaaaatac aaggctctat atgataataa
    22141 tgaaccattt gcaaagagat atgttagaaa tgtaatagaa aaagaaaaca gagcattgat
    22201 taaaaaagga gaagaaaatg caaaaatcaa aattgcagga aaactttatg atagaggcat
    22261 gtcttttgaa gatatatcag atatagttga gattgaaata agcaagttaa aagtgagttt
    22321 aggtgttttt taagggaaat agttaataaa aaaataatcg actagctctt tgtaggacag
    22381 caaaattagt gatataattt gatgtataat aaattatttt tattagataa gggggaatta
    22441 aagttgaaga ttacagtatt ataccaaaca agaagtggaa acacagaaag ggtcgctaag
    22501 ctgatagaag agggcgctaa aaaggtggat ggagtagatg taaagcttat gagacttgat
    22561 aatattgatt tagattattt aaatgaaagt aaagcagtaa tatttggaac acctacttat
    22621 ttagcaaata caacttggga agtaaaaaaa tggtttgatg aagattcaaa aaaagttaat
    22681 ttagctggaa aattaggagc tgtttttgct acatgtgatt atatatgtgg aggtccagat
    22741 gttgcgatac ttactatagt aggacatttg atggttaaag ggatgcttgt gtattctgga
    22801 ggtggttctt taggaaagcc atttatacat ttaggacatg tacattcaat tgaaggtcca
    22861 gagttacaag atgagaaggc tataatattt ggtgaaagaa ttgctactaa ggcaaaagaa
    22921 ctatttgctt aatttctata tgcataataa tgattagagt aaatttaggg ttttaatgga
    22981 gatttgaagt aaaagttata aaataaaaaa ttttccataa aattactcaa gatgaattat
    23041 aatataatta taaataaatt atattattaa aatatttaaa atcaaacgtc aatagcgagg
    23101 gaagtttatg gtatggcata tagaatatga gattttttct gcaattatag ttattttttt
    23161 aatggtatac ttttttagaa gtaaatttat acctacttta caaaacaaaa tatattgtgc
    23221 acttttaata ttctcatttt tatttataat ttcaaatatt ttaggttcat tttgtctaaa
    23281 taatatagac aaaattccaa tttttattac ttttttattg aatcagatat acttattgtt
    23341 attgccaata ccagcagcac ttgtatcatt ttatgttatg gctattattt atcaagatat
    23401 aaggtatatg aaaaaaagat tattattttt atctatacca cttataattt gtataatctt
    23461 atctattaca aatcctttta cgcatattct atttggattg tcaaaagaaa caggttatat
    23521 acgaggttgt ggatatgttg caacttttgc atcttttttc ttttatgcaa tatattcagc
    23581 atttttatct tttaaatata gaaaagcaat gcatgaatca aaaatatggg ctattagagg
    23641 ttttcttata gtttcaattg tggcaattat cttacaggca atttttttac agtatcttct
    23701 tacaggaact gcatgtgcat gtagtttact tttgacatat ctttctatgc agaatcgagg
    23761 tcttattatt gatgacctta ctggtgtact caatagacaa tcttttattc aagagctaga
    23821 tttgaatatc aatactgaac aatcaggatt tattattaca attgcgcttg atgattttaa
    23881 gtttatgaat gaaacttttg gaacaaaaaa tggagatatt gcactaaaag aagttggaaa
    23941 atatttgatt cagatacatg atgtaaacca tgtatataga atagggggag atatattttc
    24001 tattgttgtc aatagtcaat taggtataga accagatgat attatcagaa agatagaaga
    24061 aagatttaaa aagccttggc tagtagaaga gataagtttt aatttagcaa ctagtattgc
    24121 tgttgtttat tacccagaaa atgcagaaac gacagaagat gtaattgttg ctatagattt
    24181 ctctatacat gaagcaaaac gttctgagtc aaggcgagtt gtttatgcag atgcgtctat
    24241 aagtgaaaag ataaagaaga aacatgttat taaaaattgt ttaaaagaag cattaaaaaa
    24301 tgatgggttt gaagtgtact accaacctat attttctaat agcaggggca ggtttacttc
    24361 agcagaggca ttacttaggc tagaacacaa agagttaggt tttatacctc ctgatgaatt
    24421 tattccaatt gcagaacaaa caggattgat taactcaatt ggattagtag tctttgagaa
    24481 ggtatgtaga tttatagcta gtgatgagtt tgaagattta aaattggata atatagctgt
    24541 gaatctttct gtagtacaat gtatgcaaaa aaacttagct gatgatttac tttatcttat
    24601 gaataaatat aatgtatcac caactaaatt taaacttgaa attactgaga ctgtggctat
    24661 gggctctttt aatataatta aagaaacaat ggaaagatta attgatttag gtgttaagtt
    24721 tgcacttgat gattttggaa ttgcttattc tggagttact aatatgcttt ctttaccatt
    24781 ttcagtaatt aagttagata agagtttgat ttggtctatg aatgaagata gtaggcataa
    24841 acttacagtt gagacgatta tagctcttat aaataaattg aatatgaagg ctgtagcaga
    24901 aggtgttgaa accattaagt gtgctgaaga tttaatagct atggagtgtg aatatttgca
    24961 agggtattat ttttctaaac cagttccaga agatgttttt aaaaatttgt tgaaagaaaa
    25021 tacttttaca agttaacacc ctttattttt ttaattacaa ctttgttcat tgacactgcc
    25081 agcgatatat tataaaatta acacaataat aaatattaaa tttattatac atattattaa
    25141 tattaattaa tggagtaaag atttattata tattttattt aattatccta aagtgagaaa
    25201 ggaagatgtg acatgaataa aaagaaaata ttagtgccaa ttgatgggac agaaagaagt
    25261 atgcattctt tggaatttat aaaaggaata tttaaaaaag atgaagttga agtagaaata
    25321 atgaatgtaa aagaactagt atttattgat ggcatatccc tggctgaaga gataaaaaat
    25381 tctgaaaatt taggaagaag aatcttggat aaagcagcag agataatggg agagtatgat
    25441 gttaaagtac attttacttt tggatatcca ggagatgaga taattagaaa agcaaaagaa
    25501 gataatgtag attttatagt tatgacaaaa tctactaaaa aaggtcttac aagaatgata
    25561 ggttcagtaa cagcaagtgt agttaaacaa gcaaaatgta tagtgatgat tgtaccggag
    25621 tagaattaga aaggtatttg aaatatgaat aaaaagatag tagcagtttg tgaaagtgaa
    25681 agaagtttaa attctcttaa gacagctgca aatgatttag gatttgattt agtttatgaa
    25741 attcaagaaa atgataatat aaaaaatgaa ctttctattt atgatataga agatgcatcc
    25801 atagtgttat ttgttacaag tgattctata gaaagcatag agaagattga tagatttata
    25861 gatagagaat tttatgaagt tgatccaaag tatataatag aggatgcaaa atctatagta
    25921 agtgaaattt taatagactt aaattaatcg tgggtgtcgc actaagaata gagcgacgcc
    25981 tttttatata ttttacacaa gaaataaaga ggttgtatca aaatatagat aagagtcttt
    26041 ttcattgttg aaatgatgaa aatatatttg atttcataca aaaaagagta cctcataact
    26101 aaaaagttca ctttgagaca ctccattttt atatgttagt tgcatttaag gtaaaataga
    26161 agtttaatca tgttgaaata actgaattac atcttctaaa tgattgtaca ttgatgtata
    26221 acctaagtaa gagtctttac tatcaaatgc aatcattatc ttgttatggt ggctaatcat
    26281 atccttgaga gaatttctat atttaaaacc aaagtattgg ttagaagaaa ctgttttagg
    26341 tattaactca taatatttta taaaaattgg attatgagaa gctaaaatta tctctttgtg
    26401 aaattgcaag tcagcatcat aacattcttc tatcaaaccg tgagaaacct tatccaattc
    26461 ttctattgac tttaggtaag tatattttat tttttgaagt tctttagatg tagcatttaa
    26521 aattgctagt ttagtagctt cactttcgat aagttgtctt gctcttaaag attctacata
    26581 aaattcttgt atgttatgat ttttatagat ttcaccatca tcaaataggt caactttttt
    26641 aaatccttca actataggac ttgaataagg cacagctcta agtattcctt ccttacagag
    26701 tatatttatg gcatttctta caggtattct acttatgtta aataggtcag caatctttct
    26761 ctcacttggt aatttactat taattttaaa agttccattt agaatgttta atttaatata
    26821 atcaataatt ttttcagtgg catttaagct tttcataaaa actcctaaac atataatttt
    26881 tttatgattg tattatatca tagttaagag ttaaatctac ttttttataa tatgtataag
    26941 acaggataga ggccaaaata gctataatag ccaagataaa gtatccatat tgtattgaag
    27001 tatattccga tattttacca actatcattg gaaatacaga cattcctata gcataaattg
    27061 cttgaaaaaa acccattgca gtagatttct gatgttttgg tacatttttc atagactcgc
    27121 tagtaaggta agaaaggagt atacctgtag atatacctgg tagtacttgt agtacaaata
    27181 ttatattaat attttttatt gttggaacta aaaagcaata ggctgaaact aaaataaaaa
    27241 ctaaaggaat ccaaaatttt ggcccatact tagtacaaaa tttagtagaa gcaaagccag
    27301 aagaagcaac agcacacacc atgtaaaata tagaagatag acctatgagg gtagaactag
    27361 aacctaagtt tttaagaatt tgagtagtaa atgacattgt tgtagacatt tgaataccct
    27421 gttgaattaa tgccataaag gaaaaaaata caagtctttt atccttgcag atagataaat
    27481 attttttaat tgatattttt tcaggtattt tttttgaatt atgatttttt atatttaagg
    27541 ctagaatcgt tccaataact gaagacaata cactcatgat acataaggct gtcattccta
    27601 atttttcata aaataaagta ctcataacaa atccaatcaa cattcctaga ttgtttacta
    27661 atattattgt acttgtagct ttttgttgat gttctgtaga aaaaaagttg gtatagtgaa
    27721 ccatgtaaga aatccaagtt gatgatgata ttccagataa aatgttagct ataagaaaac
    27781 cattgcctcc aggagaaaag actcttataa gagatgctaa accagcaaag aaaattccag
    27841 acagtataaa tattttatgt ttatttatgg aatcagcaaa tactccaaca ggaagcctta
    27901 ataaacattg tgagattcca tatgcaccta ttattatacc aatcatattt gtagatacat
    27961 tacatgcact taaatatgga ttttggaaag gtatatatac atattgtgaa aaccagaaaa
    28021 atgtaacaat agaaagtaaa agtaattttt gattagatat ttttttcata ttatcctccg
    28081 tatggtattt ttataatgca aataatatac catttggatt ttttaatcaa gtactttctc
    28141 tattaaaaaa aatttaaata tataattatt atttacaaaa aaattatact ttatagttga
    28201 attaagaaaa cgcttatgat actataaagt taacaaattt gaatatataa cagtagacgt
    28261 gttactggta atgcaggcaa gatcgaatca atttttatag attatctata gagtactatg
    28321 ggtataatct atttatttgg ttcgattttt ttgtttaatt ggccataaaa caaaaagcct
    28381 atagttgaaa atggaggatt ttttatggat tataaaaata tagctcaaga aattctacta
    28441 aatgtaggag gaaaagagaa tgtaaatgaa gtgactcatt gtatgacaag acttagattt
    28501 aaagtcaaaa gcgcttctaa agtgaataag gataaattat ctaaaactga aggagtaata
    28561 actgttgttg agagtatggg tcaaatacaa gttgtaattg gaaataaagt aaaaaaagta
    28621 tatgatgagg ttataaaaat tgtacctcaa tcaaataacg taggtaaaaa gaatgaaagt
    28681 caagaaaagc aaggtataat taattctata ttatcagcag tagctggtat atttacacct
    28741 acaatacctg ctatagcagg ggttggtatg attaaaggta ttttatcagt tcttgctatg
    28801 tattatatga ataaaaatgg agtagatata aaagaaacgc aaagctatat tatcttaaat
    28861 gccatggctg attctatatt ctattttatg cctattatac taggatatac tgcggctaaa
    28921 gtatttaatg caaataaaat aatatctatg gtattaggag ctacactttg ttatccaact
    28981 tttactgctt tgatggcagg tgaagaatct gttagatttt taggattggc agtaacaaaa
    29041 gctacgtata catcatctgt tattccaata attattgcta tatgggctct ttcatacgtt
    29101 gaaaaagtat tagaaaagta tatacctgag gtaattaaaa taataatggt tccaacttta
    29161 tcattggtag taatgttacc tgcaacatta tttttatttg gaccaatcgg aatttatata
    29221 ggaaatgtca taaacttttc ttataagtat atttatgaat taagcccagc attgtgtgga
    29281 gcatttgtag gtgggttatg gtgtgtgttg gttatatttg gtgctcatag agcattatta
    29341 ccaataggta taagtgatgt tgctcaaaca ggaagacaga atttattggc atttgcagga
    29401 gctgcaaact tttcacaagc aggggctgct ctaggagtat tctttaaaac taaaaatcaa
    29461 ggactaaaaa caatttctat gtctgcaact ataacagctt tatttggtat aactgaacct
    29521 gcaatatacg gtgccaatct tagattaaaa aagcctatgg tatgtgccgt aatatgtggt
    29581 gcatttggag gtgcgataat gggaatgggt ggagcttatg gtaatgcatt tgcaaaccaa
    29641 ggtgttttaa ctatacctgt atatgctgaa gcaggtgcat taggtttctt aagttatcta
    29701 ggtggttgtg ctatagcatt ttttggttca gctatttcaa cttatctagt tggatttgaa
    29761 gatttggaag agtcttctaa taaggaaaat tcatctataa aagtagaaac gaaggatggt
    29821 gttattgata taacttcacc tgtagagggc gaatgtatag aattgtcaga agtaaaggat
    29881 gatgtatttg cttcaaaagc tatgggagaa ggtatagctg tgttacctac aaaaggagta
    29941 ataacagccc ctactgattg tgaagtagct tctttatttc caacattaca tgcaatagga
    30001 ttaaaattag ataatggagc agaaatgtta atacatgttg gaatcaatac agtagagtta
    30061 aatggtaaat actttaccaa acatgttaat caaggagatt tagtgaaaaa aggtgataaa
    30121 cttatatcgt ttgatataga taaaataaaa aaggttggtt atgatgtaac tacgccagtt
    30181 atagtaaaca atacatttga ttttgggcaa gtagtttctt gtaaatctag ttatgtttca
    30241 accaatgata atataatttc attagtatta gctggtaatt aagttaattt gactagagat
    30301 aagtaaattg atttaaaagg aaataagtaa atcaacaatt aaatacatct aaaagtaagt
    30361 ttattgcaat gaattgttaa agaaaataat taatatggag taaatctatt gcaatgaagt
    30421 aacaaagaaa ataattaata tagagtaagt ttattgtaat gaattgttaa agaaaataat
    30481 taatataggg taaatctatt tcaatgaaat aacaaagaaa agagttaata tagagtgaac
    30541 ttattgcaat gaatcaacaa agaaaataat taataaaaag gagaaatatt tatgaataca
    30601 ggatttccaa aagacttttt atggggagca tcatcttctg catttcaagt ggaaggagct
    30661 tgggataaag acaataaagg aaaaaccgta gccgactata attcttttaa aaagtctcat
    30721 ttacaggcag atactaaagt cgcatcagac ttttaccata attatgaaga agatattgaa
    30781 ttaatgaaag aattagggat gaaaacatat cgtttttcaa tttcatgggc aaggataata
    30841 ccagatggtg aaggagagat aaaccagaaa ggtttagact tttataataa gataatagac
    30901 aaactaatag agtgtgatat tgagccattc gtgactttat accattttga ccttccattt
    30961 aaattagtag agaaatataa tggttgggaa agtagagaaa ctgtctatgc ttttgaaaga
    31021 tttgctaaaa tatgctttaa gcattttgga gatagggtaa agtattggca acctcataat
    31081 gaacagaatt taattgttag agtggaggag agaattaata tatatgatga aacagattca
    31141 tggaagatag ataaaatgcg tgctcagatg gattataatc tttgcttagc acatgcatta
    31201 gcagtcaatg catgtcatga gatgataaaa gaaagtaaaa ttggagcagc agtatcatca
    31261 tctgtaacat atcctcttac ttctaagcca gaagatatat atgcagctag aatgaatgat
    31321 aattttaaag tgtactatat gcttgatatg catcattatg gagaatatcc agggtattat
    31381 atgaagtatc ttgaaaaaag aaatatagtt cctcacatgg aagatgggga taaagagata
    31441 cttaaaaaag ctaaaatgga ttttatagct gtaaattatt ataggacaaa ttgtgcagaa
    31501 gctttacctg aagattcaca acatccattt ggattaagag aaggaactgt tgattttagt
    31561 atgtatggac tatttaaaat gtcaatgaat cctaacttag aggcttctga gtatggagca
    31621 gcaatagacc catcaggtct tagagttgcc ttaaatgaat attggcaaag atatcactta
    31681 cctgttataa taacagaaaa tggtctagga gctaaagata tattagaaga tggaaaaatt
    31741 catgatgact atcgtataga ctatttaaga agtcatataa atgcatgtaa actagctatt
    31801 gaagatggtg tagagatgat tggatattgt ccatggtcat ttacagacct tttaagttct
    31861 tctcaaggtt ttaataagcg ttatggactt gtttatataa atagaactga ccatgaaatt
    31921 ttagatttaa aaagaatcaa gaaagatagt ttttactggt ataaagaagt tatagagaac
    31981 aatggaatag taaaataaac ataaatatat attgagggtt ttagtatgta cattacaaag
    32041 gtattaaata attcgttgct acttgcaaag gatgataatg atgaagaaat aatattgatg
    32101 gggaaaggca ttggccataa ttataaggcc gggtctgagt taaatgaaaa agatatagaa
    32161 aagatttttg ttcttcatga tgaaaatata aaaaagagta ttatacaatt ggcaacagaa
    32221 atagatgcag aatattttgg tatagctcaa atgataattg catatggaat agaaaaatat
    32281 aacttaaaac ttatgaacca tatatatttg gccttaactg accacattgc ctttgcagtg
    32341 agacgtttta aagaaggtat aatgattgaa aatcactatt tgttcgaaat caaggaattt
    32401 aatccaaaag agtatgatat aggaaaatat gctattactg tttttaagga ggttcttggt
    32461 ttagacctac cagaagaaga gattggtaat atagcaggcc attttataaa tgcacaacaa
    32521 gataatcctt atagtgatag aaataagaga agtgctaaaa ttgtaaatgc tattttgcaa
    32581 atagttcatt atcacttttc tattgtatat aataaagagt cattttatta taggagattt
    32641 gtaatgcatc taaaggcctt ttcacaaaga tttctggcta atgaaccatc aagagaaaaa
    32701 atagatttta tatatgagca agttcaaaaa aattgtaagg aagagtatga atgtgtgaaa
    32761 aaggtaggag cttatatgta taaggaatac tccagagaat taccaagaca agaggagtta
    32821 tatttgatga ttcatattca taagatttta ggagaattat gcgaaaatag ttagaatatc
    32881 ttaatatgct agtaatatta taaaaaatta aaaattaact gcactttaaa tatgaataat
    32941 tgcattactt aagggggttg tcttaaaatt gattttttta attaaatttg aagctcaact
    33001 ccttttttaa acctttatat cattacaact ttaatgttta tacgcctgta cttcagatgt
    33061 atatctactt tttacatttc tcaacatgca aatctaccat tctgtatata gtaaatgtat
    33121 tatcatgttt gttttattca agcacactta taatacgctt gattttttca caatgatgaa
    33181 atatactaat gggtgttata ggtataagaa tcgcattaca cttgaagaag taagtgataa
    33241 atgagatata aatcctcata tgataaacta ctatttcatt gaggaacata ttctaagtga
    33301 tgtcaagata ctacaatatg actaaattcc tagtgataaa aaagtctacg aatgagtgta
    33361 gaaaggggaa ctaagatgaa taaagtttta attatagatg atgataaaga tctttgtatt
    33421 ttgttaaaaa agagtatttc aattgaacag attgaagcaa actattgcca ttctgggaga
    33481 gatggactgg ttgaactttc aaaacaagat tatcagttag tagttctaga tgtgatgatg
    33541 ccaggtatgg atggttttga aactatggaa caaatacgaa aatatagcag tattcctatc
    33601 ttaatgctga catcaaaaag tgataattac agcaaagtgc atggattgcg agctggtgca
    33661 gatgactatc taaccaaacc atttgaaatt acagaattta ctgctcgtgt actgtcttta
    33721 atccgacgtt acacccgttt taatccaaaa aatgaggagc cacagcaact ttctttcaaa
    33781 ggtttgttga ttgaccttga ccagcataca gttactacca atggcgaacc tatgttgctt
    33841 ccacccaagg aatttggtgt acttctttac tgtgcaaggc atcagggtaa gattttgaca
    33901 aaacagcaga tttatgaagc cgtgtggggt gagccatatg tatatgatga cagcaatatc
    33961 atggctatta tcagtcgcct aagaaaaaaa attgaactag acccatcatc tcccatctat
    34021 ttgcaaacaa taaaaggaat tgggtatcaa ttcaacacgg aggtatgaaa atggatgaac
    34081 aaacgataat tcttttctta ctcttgctgt cgattggtct actttttctt tccatatttg
    34141 ctttttccaa gcttgggcat attcacaaac gcttaaaaga tatagaggag atactcgctg
    34201 atgtacaaat tggagacgaa aatcgtaaaa tactaattaa gccatgtgat gttatggctc
    34261 cattggttta tcagcttaat gagattgtct acgattatga aaataagtta ctttctctga
    34321 aaaagtcgga taaagctagc aaacaactta tgacaagttt atctcatgat gttcgtacac
    34381 cattaacaac tctgattggt tatctggatg ctgtacacag tggtatagtt atcgaacaag
    34441 agcgggagga ataccttgaa atcgctaggc gtagagccta cgacctcaag gattacattg
    34501 atgttctttt tgactggttt cggttgaact ctgatgaatt tacgctgtca atagaatctg
    34561 tggaaattgc agagttgtca cgcaatattt tgaaagactg gattcctata ttccatgaaa
    34621 agaaactgaa ttttgaaatt gatattccag aaaatcgact aatggtaaac ctcgacccag
    34681 atggatattc ccgtgtggtc aataatctgg ttcaaaatgt tcttgctcac agtaaggctc
    34741 ggcaaatcaa gattaccatg agtgaggatt ccagaatggt attactccgt gttgaggatg
    34801 atggtgttgg gattgccaga gaaaatttac cacatatttt tgagcgactg tataagtgtg
    34861 ataaaggacg ttcagaaaaa ggaagtggtc ttggtctatc tattgtcagt caaatggtgg
    34921 agcgaatggg tggtcaggtt tccgtagaaa gtgagattgg aaagtatacc gtatttacag
    34981 tgagcttacc attaatataa aattgttttt cccccatgtg acatgtatac acagggggat
    35041 tttttgtaag ttataaagtt gcaaggttaa tacaaggttg ttgcaaggtt aatgtaagat
    35101 tgaggtggta tgataacttt aataaacaaa ggaggctttt attatttatg aataatttaa
    35161 ttattgaaac aaaaaatctc actaagcaat atggtgctca aaagagcgtt tctaatttga
    35221 atattcacgt tcagaaaggt cgcatttacg gattgctagg aagaaacggt gcgggtaaga
    35281 cgacaactat gaaaatgtta ttgggcctaa caaaaccaac tactggagaa attaaaatat
    35341 ttggtcagga cattcacaat aacgagaaga agcttcttcc tcgaattgga tgtttgattg
    35401 aatcaccagg gttttatcct aatctgacag gaacagaaaa tctcaaaatc tttgcaaggc
    35461 ttagaggaat accaaaaaaa aatgcagtag aatcagcact ggatgtagtc ggtttgccaa
    35521 acaatgacaa aaagttattt tctcaatact ctcttggtat gaaacagagg ttggcgattg
    35581 ctcttgccat tatgcatgac ccacaactgt tgattttgga cgagcctatc aatggacttg
    35641 atcctattgg tattgcagaa gtaagaacgt ttattcgtga tctctgcaca gaacgaggta
    35701 aaactatttt gatttccagt cacattcttt ctgaaattgc cttgttggca gatgacattg
    35761 gcattattga ccatggtatt ttgttggagg aagaaagtct tgcccaatta gaagaaaaaa
    35821 acagtaaata catacatttt gctgtatctg atgcagcaca ggcagcaagg cttctggaaa
    35881 cccaacttaa cctgaaaaat ttcaaagtag cagataatta caatattatg ctatatgata
    35941 cagatgtttc tgttgcagaa ataaatcgtg ctttcattct aaacaacatt gaggtatcag
    36001 aatctcattt atgcgaagat actcttgaag attacttcaa gaaagtaaca gggggtgaag
    36061 gaattgcttg atataatttc atgtgaattt tcaaaactca agcggttaaa atttatactg
    36121 atttctattt taggtgcttg cttatttcca attcccgcaa caattttgat tgcaaaggac
    36181 aacttgccct ttgagcaatt gttcaaatta gttgtcaatt ttggatattt cttgctatta
    36241 ccaattgtat taagtattgt tgctagccaa ctatttttta tagaaagaga taatgatgta
    36301 ttaaaaaatc ttgcaacagt gccagtgcca aaaggaaaac tggctctggc aaaattggct
    36361 gtgttgctgt ttatatcatt gttctactct gttgcagggt taggagctac tatcattgga
    36421 ggtttcattg ttggaatagt agagggggtt gctgtaaaat taggaatgag cattgctttt
    36481 ggaattatgt tttttgttac tgtacttcct gttgtggtac tcattgtata tttcaatcgc
    36541 agctatattt tttctattat actttctttt gtatatgcta ttttcaattt tagtatatcc
    36601 ttaaatatta tcaattttga accaaataac ccactattaa gcgtattacc tgctcctgtt
    36661 ataatgcgtt ggtggatggc attttgggga gatcccactg gcgaatacac ggtacttaga
    36721 cagccatatt tgctctcaac tcctgcttgt gtaggtattt tatgtttgat aaccattata
    36781 gcagtcctgc tgatttgtat gatatacaaa aagcaggaga attaggaggt atctatgctt
    36841 gatataatta ctacagaatt tcaaaaaata aaaagatata atattctatg gattggtgtt
    36901 gttgctgttc tgttttcagc actattggca gtttttcagg ttgtaagttc acacggcagt
    36961 gaccctctaa cgtatgagag ctttgcaaac ggagttatct ggaataattt cagtcttagt
    37021 tttccatttg ggattacact tattggagga tatcttatta accgtgaata tacagaccaa
    37081 accttaaaaa acatcctaac tgttcctatt tcattacgca aattgctagt gggaaaatta
    37141 attgcggttg gaggaattac tgtattgtta agtcttttca gcttcttatg cacatttatt
    37201 ttggggttgt tattttgcaa tatcaatata tctgttatac tcgttgtaaa atccttagtt
    37261 cagattttgt ctgttaatct gtattgttat gttgctgttt tgccgattat tgcttatttt
    37321 ggtcgtaaac aaaatgcatt tctgacgggt gtagggattg catttgtata cggtttttgt
    37381 ggtgtgtttg ttgctggaag aaatctgaca gacttttatc caatcacagc aggtcttggt
    37441 ctagttggat acaacaatgg tgctggtact gtttatcagc cacttatcgg tgctatgact
    37501 ttgattgtaa ttctaatctt gacaactatt ctacttgtat ttacacctaa ttatgataaa
    37561 gttatgacca tatctaagaa aaaagggata aagcataaaa agtattctca taaataacat
    37621 aaatattgtt tctattattt aagttgctag acagtgaaaa gaaaaaatct gtcgtacagt
    37681 ggctatatgc tcatgtattc aagaagctac agttttgatt tttcataact gtagcttctt
    37741 tttgtattta ttaaatcacg actatcataa tacttgcaat aggtatagta acaagagaga
    37801 gtactgtcat atgtgtttta tatattacat taagtatatt ctaaaatata tgttttaaat
    37861 aatatatttg aaaataggaa tatttaaata aaaaaaataa tattatatat agttgacaaa
    37921 aattggcaaa tgatatacta tataaatata gaaatagtaa tcattactat tattaaaaag
    37981 ggaggaatta attatgaact taaaaggaac taaaacagaa aagaatttaa tggcaggatt
    38041 tgcaggagag tcagaagcaa gaaataaata tacatactac gcttcaaaag caagaaaaga
    38101 aggttataat caaatagctg ctatatttga agaaactgct aacaatgaaa aggaacatgc
    38161 taaattatgg tttaaacttt tacatgatgg tatgccttca acagaggaaa atttaaagga
    38221 tgcagcagca ggtgaaaact atgaatggac tgatatgtat gcaaaatttg ctaaagaagc
    38281 tagagaagaa ggatttgaca agatagctta tttatttgaa gctgttggaa aaatagagaa
    38341 agagcatgaa gaaagatact taaagctttt agaaaactta aatgaaggaa aaatatttaa
    38401 aagagatgaa gaagttgttt ggcaatgtca aaactgtggt catgtgtatg taggtactga
    38461 agcaccagaa aaatgcccag tatgtgacca tccaaaagca tattttaata taaaagctga
    38521 aaattattaa aaattatcat tattaaaaag gaatgttaac tatgaaattt tctaaacaac
    38581 gagaactgat tttaaatgaa atattaaata atccggttca tcctactgcg gattacctat
    38641 atgaaaactt aaaaaaagat aatccgaatt taagcttagg aactgtgtat agaaatttag
    38701 ctcagctaac ggaacatggc tttataagaa aggttagtat tccagggtat ccagatagat
    38761 ttgatggtcg aatagataat cactatcata tcatatgtga agtatgtgga gaggtatacg
    38821 atttagaatc cgaagttctt aataatttac aagaattaat atctgaggag acagacataa
    38881 aaataacatc ttataacata agttttaaag ggatttgtaa taattgtaaa aggtgtagcc
    38941 aagtaggtta gttttcaaat tctaaaaata attaatgagg tgagtttatg tgtagtgaac
    39001 aaaaattttt tatatgtgag acttgtggaa accttgtagg aatgatacaa agtggtggtg
    39061 tacctatttt ctgttgtgga aaacctatga aggaacttgt tcctaataca acagatgcag
    39121 cagttgaaaa acatgtacct gtaattgaag tggatggaaa taatgttact gttaaagtaa
    39181 gtagcacaac tcatccaatg actaaagaac atcatatagc atgggtgtat cttatgactg
    39241 aacaaggtgg tcaacgcaaa tgtctagcag tagatggaga acctgtagtt aaatttgctt
    39301 tgaatgatga tgataaagtg atttctgcct atgcttactg taatttacat ggattatgga
    39361 aggctgaact gtaatattta aataaattga gtcaaaaagg aggctataaa tgtattttca
    39421 tacaaatagc ctcctataaa tttatataaa ttcaagtttt aattttgttt aatgtcaata
    39481 taatataagg agaaaataat atgtcaattt ataaatgtag tgtttgtgga tatatttatg
    39541 atgaatctaa gaatgataaa acatgggatg aattaagtga agattgggaa tgccctgtat
    39601 gtacaaaagg tcgtagttat tttggaaaga taagtactgt ttactatgaa gaagatgaaa
    39661 agatagcaga agacatagtt gaagatgaat ctaaattaaa tactgaaaaa gagggagatt
    39721 taaattactt aagtacatat ttaagaagag atgatgaagt tgagaaacat atggatataa
    39781 ttcacgaaat ggctgttaca ggaaaatcta taatagaacc tatgagaact aaactaccag
    39841 taatttcttg ggatgatatt ttaattatgg gtgctcaatt aaatccatta cctttaaatg
    39901 agcatgatga agtaaataca acaacaataa taggaaaaaa agcaaagaaa cctatgatta
    39961 tagaaaatcc agtttatatt tcccacatgt catttggagc tttgtctaaa gaactaaaaa
    40021 tagctttagc aaagggtgca gcccaaaata agacagctat gtgtagtggt gaaggaggta
    40081 tattaccaga agagaaggaa gcttcataca agtatatttt tgagtatgta ccaaataaat
    40141 atagtgtaac tgaagaaaat cttaaaaatt ctgatgctat agagataaaa attggtcaag
    40201 gaacaaaacc tggtatggga ggtcatcttc ctggcgaaaa agtaactgaa gaaatagcaa
    40261 aagtaagaaa taagcctgta ggtcaagatg taataagtcc atcttgtttt gaggaaatac
    40321 aatccaaaga ggatttaaag aaacttgtag atgaacttag agaagtttca gaagggcgtc
    40381 caataggtgt taaaatttca gcaggtcata ttgaaaaaga tatggaattt atagcttatg
    40441 ctaaacctga ttttgtaact attgatggtc gtggtggagc tactggagca agtccaaagt
    40501 tgcttaaaga tgcaacttca attccaacaa tatttgctct ttatcgtgct agaaaataca
    40561 tagatacaca tggattagat atagatttgg ttataacagg tgggcttcgt atatctactg
    40621 attttgctaa ggcaattgct atgggggctg atgcagttgc tattgcaagt tctgctctta
    40681 tggcagcggc gtgtcaacaa tatcgtatat gtggttctgg taagtgtcct gtaggagtag
    40741 ctactcagga tgaggaattg agaaaaagat tacatataga aaatagtgct aatagagtgg
    40801 caaacttttt aaatgtaagt ttagaagaac ttaagacttt tgctagaatt tctggtcata
    40861 aagatataca tgatttaagt gttgatgatt tatatactgt taactctgaa atatcaaatt
    40921 atacaaacat acagcatgta tagattgaag tttgaaacta ttagatttta gacagctata
    40981 aaagtaaatg ataaatatat tttataaaag agagtgtctt aaaatgaact ttttagttca
    41041 taagtcactc ttttttgtat gaagccaaat atatttatca ttttagcaat gaaaaagaat
    41101 cttatctctt tattttgaga tagactcctt ctatttatga aaattaaaga tattaaattg
    41161 taaaatattc tgtgatgtcg tactattaaa ctaaagattc tgtactttaa agtaaataaa
    41221 aatttaagga gtgattatta tggaaagatt gaagatacaa gttttagtcg acaataatac
    41281 ttatattgat agatactttg ttggagaacc agcagtaagc tattatattg agattgatgg
    41341 aaataggatt ttgtttgact cagggtattc agatgtattc atatcaaacg ctgaaaaatt
    41401 aaatatagat ttaggaaatt taactcatgt tgttttttct catgggcata atgaccatac
    41461 aagaggtatc cagtttttag aaaataggta tgatttatct acagttgaac ttatttcaca
    41521 tcctaactgt tttataccta gaaaacatgg agagaaaagc ataggagctc cattttctgc
    41581 tgaggaaatt aaaaatattt ttatgtataa tcctaaggat aagccattta atctaagcaa
    41641 gaattgtgtg tttttaggtg aaataccttc tataaatgat tttgaaaaaa gagctaaaat
    41701 tggtaaatgt aaaataggag atttgtggga agatgattat gttttagatg attctgctat
    41761 agtttgtaaa actgataaag gtatttttat tgttacagga tgttctcata gtggaatttg
    41821 taatatagta gagtatgcta aaaaggtatg tggagatgat agagttattg gtatactagg
    41881 tggttttcat ctttttgaat tgaataatag gttagatagt acaatacaat atttggataa
    41941 agaagaaata agaatgttgt acccttgtca ctgtgtttct tttaaggtaa aagcgaagat
    42001 gaatgaaata ttgaatataa atgaagttgg agtagggctg accataagta tatagtattt
    42061 gaaagtatat aagatttaag ttgaaggtta aaaagatatt ttctatagaa aatatctttt
    42121 ttgttacgtt tattttaaga gaaatcaata tacttttata tgaaatattg taaaaaaatt
    42181 tatttttaat gagaatatat tttcattaat aaacaatttt attatgtatt aataatgtta
    42241 gaataaatat aaataaatca aagttactta cattacagta tattttttca caaaatatat
    42301 tgatttattc ttttaaagtt tgataattcc aatgaatgta ataaaagaag gaattttata
    42361 ctatactatt attattataa aataataaag aaaaaattat ataataataa agaaaaaatg
    42421 tataatattt aacattaaaa aagatatttc ataaaattaa aaaacaaagt gaatttgaat
    42481 actatttaaa aaataaaata aatatataaa aaatatttaa tataaaggta gaaataagtt
    42541 gaaaatgtaa agtcattgga aaaatatagt tgaatttaat gagcaaaaat gttattgttt
    42601 tatcaataaa gtgttaaaat aaaaactttt aatatcattt tagggaggat gatttcatgc
    42661 aaaaaagtgt aaagaaagca aaagtaacgg gctctatgtt agccattttt ggtgttgcaa
    42721 gcgttctttt tagttcacat gcaggaggag gatttgctac agggaatcaa gaaactcagt
    42781 actatgtgca gtatggatgg acagcaccac ttatggcaat tttagcaatg attatactta
    42841 ctgctaccat gagagaagtt atcataatgt ataataataa caattgtagg aattataagg
    42901 atttattttg tgagctttgg agaccatatc caaaacttga aataatatgg gagatatatt
    42961 actatctaat ggttttaata gctgtaagtg ctgttatagc aggtgcagca gcagtatttc
    43021 aaagtatagg agtaaattat tttgtagctg tatttattat tggagttgta cttcttgtct
    43081 ttactatatt tggtgctatg cttgtatcta aagcagctac agcaatgaca atagctattc
    43141 tagtatgtac tcttactatt tttattgttg gtataaaagc taaagtacca gaaataactg
    43201 aaatattatc aaatagaacg agtttcacac ctggctatat caagccaata cttaatactt
    43261 ttatttatgc aggttttcaa tcggttgtta tacctacact tgcaggatgt tcaagaccac
    43321 ttcttaagaa ctcaaaagaa gctactaagg caatgataat ttcatttgtt atgaatgcaa
    43381 ttgcattagg acttgctgta actatgctaa tgggatggta tagagaaatt attgctgctg
    43441 ggcaaacaac actccctact ctttatgttg caggtcaatc tggaaatcat actatataca
    43501 taatttataa tgttgcatta ttcctttgtt taatgtctac aggagtaact actatatttg
    43561 gtcttgtaaa tagatttgaa gaccataaag cactttcttt cctttcttca agaatgaaaa
    43621 gaagggtatt tacagcttgt gcaataatgg tagtgtcaat gcttatatca cttacaggat
    43681 taagtaatat tgttaaatat ggatatggat attgtggtta tcttggtcta ttcactatag
    43741 taattccatt ccttacacta ggacattata agaataagaa gtttgcaaag gaaaatccag
    43801 aagctaaatg gccagcggaa ttaaatgaaa atgtaaatta gatgtagtag caaaaaatat
    43861 tgctaaagag aatactatag ataagaatac tatagataat atatctgcat gtttattaag
    43921 attatttgca aaatctaata ttaaacaact ataaacaagc aatataaaac taagaataaa
    43981 agataaaaag agggtgtctc aaaatggact tttagtttat aaggcactct tttttatatg
    44041 aagtcaaata tattttcatt attttgacaa taaaagagac taatcctact ttggatagcc
    44101 tcttttttct ttaatataaa atagtataac agcaaagtat agattgatac atgttttctg
    44161 tagctttcta tatattacag tgtttgtgtg gcattggtat tttaagcaat ctataaatta
    44221 taattctata attcttctac taattttaga ttctatagcc gtctctattt cacttaacat
    44281 tcgttcattt ttagggtcaa taaaagcaca tgtatagcct tcttcaccag ctctaccagt
    44341 tctaccaata cggtggatgt agtcttctgg tgtttctggt aaatcgtaat tatatatatg
    44401 acttactcca gatatatcaa gaccacgaga agctacatct gtagctatta agtattgtat
    44461 atctaaattt ctaaatgatt tcattattct ttctcgtttt gattgagcaa tatcactatg
    44521 aagtttttga caattatatc ctcttatagc aagagcttct tcaagattgt caacccttct
    44581 cttagttcta caaaatatta ttgccataaa aggattatct tcatctagta ccttacataa
    44641 ggcatctaat ttttttctat ctgtagtttc tactacttct tgttttatat tattaagagt
    44701 gatttcttct ttttgaatag aaactacaac aggatttttt gtgtatctat aagctaattt
    44761 ttttacttga gaatttatag ttgcagaaaa gcatagtgtt tgctttttgt ttgaagtctc
    44821 ttttaaaata gcttccactt catttttaaa tcccataagc aacatttggt ctgcttcatc
    44881 taaaacaaaa gtctttaact tactaaggtc tattgttttt ctatttagat ggtctaaaag
    44941 cctacctggt gtagctataa tcatatgaat atttcctttt agtttcttta tttgagaacc
    45001 aatatctttt cctccatatg ctgcaagaat acttacatct ttagattctt taagtttcat
    45061 agcttcttct gttatttgaa tagctagttc tcttgtagga gaaagtataa gtacttgtat
    45121 atcatttata tctaatgata tattttcaaa tatcggaagt aaaaaagcta gtgtttttcc
    45181 tgttccagtt tgagcttctg ctattacatc ttttccttct tttattagtt taatactttc
    45241 tttttgtata ggtgtaggtg ttgttattcc tgattttttt agaatattta ttgtattttc
    45301 actaatccct aagcttttga aatccattgt tatcttacct ttcatgaaaa attttctttt
    45361 ttattaacca attaataata tcatatttat aagtattttt agtaaatttt ttaattatta
    45421 tttatatagc ttaaaaatat attaagatac tttaaaatgg aatgtaactt aaattaaatt
    45481 ttagtaggaa ttttataggt ttatttttaa aggttttttg aaaataaatc tatttaaaaa
    45541 ttaaattaaa atgcaagaaa aacataataa ctttcatttt taagaagttt tcacaaaaaa
    45601 gaaaaaatat agtgcaataa atgatacaaa gtaatataat agattacaag atatgaaaag
    45661 ctaaaaaaat aaattgcaaa tgaaattaaa atgaataaaa aataaaaaaa taatcataag
    45721 ttagaggtat caatgaaaaa taagacttaa tgttttaaaa ttaaaagtat actaaggggg
    45781 gcattaatat gtgcgttata tcaaaagata gagcaaagga aataaaaata gtagatacta
    45841 ctttaagaga tggagagcaa acagctgggg ttgtatttgc aaatagagaa aaaataatga
    45901 ttgctgaaat gttaagtgac ctaggtgttg accaaattga agttggtata cctactatgg
    45961 gtggagatga aaaaaatgta ataaagcaca tatgtagtag aaatttaaaa tcagatataa
    46021 tggcttggaa tagagcagta ataaaagatg ttgaagaatc tatttcttgt ggtgttgatg
    46081 cagtagctat atcaatatca gtatctgaca ttcatataga aaataaattg agaacttcta
    46141 gaggctgggt tttagaaaat atggctaaaa cagttgaatt tgcaaagaaa aatggattat
    46201 atgtttcagt aaatggagaa gatgcttcaa gagcagatat agacttctta actgaattta
    46261 taaatgttgg aaaacaagca ggggcagata gatttagata ctgtgataca gtaggagtta
    46321 tgaatccttt ttctataaag aatgcaatag aaactcttta tgaaagaact aattttgata
    46381 tagaaatgca tacacataat gactttggga tggcaactgc aaatgcactt gcaggaatag
    46441 cagcaggagc aaattatgtt ggtgttacag taaatggatt aggtgaaaga gcaggaaatg
    46501 cagcattaga agaagtttta atggcactta agtgtgttta taaatgtgat ttaaataata
    46561 tagatactag aaaatttaga ggaatatgtg agtatgtagc acaggcatca ggaagaatac
    46621 ttcctacatg gaaaccagta gttggggata atatgtttat acatgaatct ggtatacatg
    46681 cagatggagc tttaaaagac ccacataact atgaaccatt tgacccaagt gaagtaaatc
    46741 ttgaaagaaa aatagtaata ggtaaacatt caggaagagc tgcagttgta aataagttga
    46801 gtgaatatga aatgtatatt tctccagaaa acgctaccaa gctattaaat gctataagag
    46861 ctacatctat aagattaaaa agaagtttaa tggataaaga aattcttcaa ttatattgtg
    46921 atatactagc acatgagaaa ggcacaacag aagaagaagc agttagaggt tcatatattt
    46981 aagatataat tgtttaggag gaaaatatgg gagataatat agtttataaa ataattaaaa
    47041 aacatatagt agatggagaa gctgttgctg gaagttcaat tggtataaaa atagaccaaa
    47101 ctttaacaca agattctact ggaacaatga catatcttca actagaagct atgggaatag
    47161 ataaagtaaa gactaaaaga agtgtggcat ttgtagacca taatatgtta caacaaggat
    47221 ttgaaaatgc agacgaccat aagtatatac aaacagtggc agataaatat ggagtttatt
    47281 tctctaagcc aggaaatggt atttgtcatc aagtattttt agaaagattt tcaacaccag
    47341 gagatacact tttaggttct gatagccaca cacctactgc tggaggtgtg ggcatgatgg
    47401 ctattggagc tggtggatta gatgttgctt tagccatggc aggaggagca tactatataa
    47461 aagcaccaaa agtctgtaag gtgaatctag ttggaaaatt aaataatatg gtatcatcaa
    47521 aagatataat attagaagtg ttaagaaaac aaactgtaaa aggtggagta ggtaaagttt
    47581 atgaatatgg tggagaaggt gtcaaaagcc tatctgttcc acaaagagct acaataacaa
    47641 atatgggggc tgaacttgga gcaactactt caatcttccc aagtgatgaa aaaacactag
    47701 aattttttaa gagtcaagga agagaagagg catggataga gctaaaacca gatgcagatg
    47761 cagtttatga tgaagagatt actataaact tggatgaatt aaaaccatta gctgcaaaac
    47821 ctcatagccc agacaatgta gatgaagttg aaaatatagg caagattaaa atagaccaag
    47881 tggcaatagg aagttgtaca aattcttctt atgaagactt aatgaaagta gcacaaatcc
    47941 tgaaaggaaa taaagtacat aaggatgtga gtttggtaat agcaccaggt tcaagacaag
    48001 ttatggagat gattgctaga aatggggctt tggcagatat aataagtgct ggagctagaa
    48061 tactagaaaa ttcttgtggt ccatgtattg gtatgggtca atctccaggt actgactctg
    48121 tgtctttaag aactttcaat agaaatttct atggtagaag tgggactttg tcagcacaag
    48181 tatatttagt aagtccagaa gtggcagcag taagtgcaat caagggagtg cttacagacc
    48241 caagagaatt tgatattaaa tttacaaatt tagatgtaaa tgaatttttg atagatgata
    48301 gcatgataat taaacctgct gatgtaggaa gtgatgtaga agtagttaga ggacctaata
    48361 taaaaccttt ccctcttaat acagagctaa gtcagtctat aggtggaaaa gttatattaa
    48421 agacagaaga taatataact actgaccata taatgccatc aaatgctaag ttacttcctt
    48481 ttagaagtaa tataccgtat cttgcaaact attgtttcaa tactgtagat acagaatttc
    48541 ctcagagagc aaaagacaat aatggtggat ttatagttgg tggagataat tatggtcaag
    48601 gttcaagtag agaacatgca gctttagcac cattatatct aggtgttaaa ggggtaatag
    48661 ttaagagctt tgcaagaatc cacaaggcta acttgataaa tagtggtata attccaatgg
    48721 agttttgtga tgagaaagat tatgaaaata tatctctttt agataatctg gagataccaa
    48781 atattttaga caatctaggt agtggaattt tagaagttaa gaatacaact aaaggaactt
    48841 cttttaaggt caaagtagaa ttgtcagcaa aagaagttga tgtattaaaa gctggtggaa
    48901 aattaaacta cactaaaaat caagctaatt aatatgaaaa gagggaatat tgaatgtata
    48961 aagtgacact tataccagga gatggaatag gaccagaagt tgcgaaagct atgaaaaagg
    49021 tagtagaagc tactggagta gaaatagaat gggaagaagt taatgcagga gaggcagtta
    49081 ttgaagagta tggtactcca cttcctgaat atattataga tagtataaaa aagaacaaaa
    49141 tagctataaa aggcccaatt actactcctg taggtaaagg atttaggagt gtaaatgtaa
    49201 ctttaagaca ggcattagat ttgtatgtca atttaagacc tattaaaagt tttaagggga
    49261 taaaatcaag atatgaagat gttgatttag tggttgtaag agaaaataca gaagatttat
    49321 atgctggaat agaacataaa ataggtgatt atgcagctga aagtataaag ataataacaa
    49381 gaagtgcaag tgaaagaatc gttgattttg catgtaacta tgttaaagat aataagagaa
    49441 aaaaagttac agctatacat aaggcaaata taatgaaaat gtctgatgga ttgtttttag
    49501 atgtgtttag agaagttgca tcaaaacatg gtgtagaata tgatgatttg attgtagatg
    49561 cagcagctat gaacttagtt ttaaatccag aaaattatga tgtaatggta atgccaaatc
    49621 tttatggaga tatactatca gatttaggtg ctgggcttgt tggaggttta ggtataattc
    49681 caagtgcaaa tattggtaaa gattgtgcga tatttgaagc tgttcatgga agtgctccac
    49741 aaatagcagg tcaaaataag gctaatccaa cagcacttat tcaatcatca gtaatgatgc
    49801 ttagatactt aggtgaatat gaaaatgcac aaaaaataga aacagcttta gaaaaagtat
    49861 ttcttgaagg aagtaaattg actgtagatt tgggtggctc agcttctact acagagtttg
    49921 cggatgaggt gtgtaagtat attgtataga ttttatttag ggaaaaagta aaatatagat
    49981 tgaaggaaag aggctttctc aaaatagaga taagcctttt ttattggaat gataaaatat
    50041 atttgatttt atacaaaaga gagttcctca taaacgaaaa agttaatttt gggatatcca
    50101 ttttaatttt aaaattaatt gattaatatg caaagaaaga ttaaataaat ttattatttt
    50161 taattgaact ttcaaccaaa atatggtaaa atttaaaaaa gttgaacttt caactaaaaa
    50221 tgaatatatt gattatgtga aattttataa aacagaaact atttgacttt agccatagta
    50281 gtttcagtgg aggtgtgttt gattaagact ttagatagta atatattaag agaagtaggt
    50341 actttatcta gagcagtaaa ttcaataaat gatattaagt acaaggaatt aaagttacaa
    50401 aaaggacaat ttacattttt gacaagaatc tgtgaaaatc ctggtataaa tcttgtggaa
    50461 ttatcaaata tgttaaaggt agacaaggct acaacaacca aggctataca aaaattaata
    50521 aaggcaggat atgtagataa aaagcaggat aagtttgata aaagaggata taatttaact
    50581 ccaactgata aatctttgga agtttatgag ttgataattg aagaagagaa tagaagtata
    50641 gagatatgtt ttgataattt tacagatgaa gaaaaacaag tggtaactaa gttattagaa
    50701 aaaatgagca aaaacgtaga aaatgaatgg tttaaagtaa agagatagta aataaataca
    50761 ttaacttaag gagatatttt tatgattaga aaagcgaata tgaatgattt agaaagcatt
    50821 atgcaaatta taaaatctac agtggaagaa atgaagactt ataataatac acaatgggat
    50881 gaaaactatc cattagaaaa agactttgtt tcagatatta agaaacaaga tttatatatt
    50941 tatgaagtgg atggagaagt agcagggttt atatgtctta attatgaaga gccagaagaa
    51001 tatttaggct taaattggtc atctaataaa aaagcaatgg taatacatag aatggctgta
    51061 aatccaaact ttagaaagac aggaatagca tctaagttag ttgattttgc tgaaaaatta
    51121 gctgtagaaa acaatgtatc atacttaaag agcgatacat attcaataaa ctcaaaaatg
    51181 aatttattac ttacaaagtg tggttttata aaaatcggag aaatgagttt tttaggaaag
    51241 gagaaatctt tctactgtta tgataaaata ttataaagag catttataat acaagggata
    51301 aataatagat tttcagcatt agtaagggca taatataacc tagtgtatgc tattatgaaa
    51361 gggatgattt atatgattgg atttctaaag aaaagaagaa gtattagaaa atacaaggat
    51421 gttgaagtag aaaaagaaaa attagataaa atattaaaag ctgctctttt agctccatca
    51481 tcaaaggggc ttagaacatg ggaatttata gtggtagatg ataaagaaaa gctaattaat
    51541 ttatctcaat gtagaactaa aggtggtgga tttttcttaa aaaatgcacc tttagctatt
    51601 gtaattattg cagataaaga aaaaaatgat gtttggatag aggatgcaag tatagctgct
    51661 tcatacatac aacttcaagc tcatgaacta ggtttaggtt cttgttggat acaagtaaga
    51721 aatagaatgc atgatgataa tatagaagct gataagtaca ttagagaaga attaaaagta
    51781 cctagcaagt acagtgtaga atgtataatt tctataggat atcctgatga agaaaagaaa
    51841 gcatacggtg actctgattt agactataaa aaggttcatt ttaacaactt ttagtatata
    51901 atatgttgta ttaagacatt atattttttt ctattgttaa tatatactta aaattgtaaa
    51961 aatatatctg aattttacta acttatctag gggttatgta caaggatttt aaagataaat
    52021 atagaaatta atgtttataa tcgatacata acttgagtaa caaaatttaa ggaggttaaa
    52081 gtatgggtat atttaaaaca aaaatggatg aggactggaa agtaaactac attaaagagt
    52141 ttaatgaaat gagagattct tatgagagta aacttcaaaa aaaacagttt gaggtagata
    52201 gtttgaaatc agaattggat agactaagaa gctataaaaa tagccttaag ccaaaagaaa
    52261 aacaaattac tgatgatgat ataaataata taaagagttt aaggagagat ggcttaagct
    52321 ataaagaaat ttcaaatcaa acaagttgga gcaaagcaac tgtaagtagg gtattaaatg
    52381 gactttacga ttagcatata catggggtga tttaaattgg gatgaagtat agttacaaaa
    52441 aatgcataat agattctatt ttattgatgt ttatagttca aatattaagg atgattttga
    52501 attatgtact tctaagtcaa tttgaattta ctcttgaaaa ttttaatatt ataaacttaa
    52561 tttcttttac attagttggt ttatcgttaa ttttattttt aaaagataat tctttgtata
    52621 acaaggttag aaatagaaaa atcacagaag cttttgaaga aaataaaaac aatatactta
    52681 ttgaaaagtg taagctgata ctttttgttg tggttttatc tttagcaata attgtaactt
    52741 attgtactaa gggatatgta ctttttaatg taactatgat gactttgtct gtattgatag
    52801 tcccaatatt tgaagagtta ttttttagag aatatatatg gaactatcta agtaatttta
    52861 taaagtcaaa gagtaaaatt atctgtataa catctatact atctggaatt tataatatag
    52921 gatacataga tgttataaga aattatgtaa tattgtataa caattcaagc tacacctttg
    52981 aagttattat ttcaaaaatt atgataggta ctgtttttgg tattgtactt ggattagtta
    53041 agtataggtt tagagatgta gggttttgta tattattgag gagcttattt gctatattta
    53101 ttaggtagat agtataatcg gtttataagg ttgttttaaa tttaatttta aatcaacctt
    53161 attttatttg tgttttataa agcacttata tattaataac taataaattt aata
//
LOCUS       DAEPHU010000021        51929 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 01A10CD0081
            SAMN05941466-rid12468953.denovo.021, whole genome shotgun sequence.
ACCESSION   DAEPHU010000021 DAEPHU010000000
VERSION     DAEPHU010000021.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941466
            Sequence Read Archive: SRR6291087
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 51929)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 51929)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068158.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 22:43:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,892
            CDSs (total)                      :: 3,805
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 87
            rRNAs                             :: 8, 1, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 55
            CDSs (without protein)            :: 55
            Pseudo Genes (ambiguous residues) :: 0 of 55
            Pseudo Genes (frameshifted)       :: 21 of 55
            Pseudo Genes (incomplete)         :: 28 of 55
            Pseudo Genes (internal stop)      :: 16 of 55
            Pseudo Genes (multiple problems)  :: 8 of 55
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..51929
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941466-rid12468953.denovo.021"
                     /strain="01A10CD0081"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            27..101
                     /locus_tag="KR231_001332"
     tRNA            27..101
                     /locus_tag="KR231_001332"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:59..61,aa:Thr,seq:tgt)
     gene            116..197
                     /locus_tag="KR231_001333"
     tRNA            116..197
                     /locus_tag="KR231_001333"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:150..152,aa:Tyr,seq:gta)
     gene            210..293
                     /locus_tag="KR231_001334"
     tRNA            210..293
                     /locus_tag="KR231_001334"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:244..246,aa:Leu,seq:tag)
     gene            317..391
                     /locus_tag="KR231_001335"
     tRNA            317..391
                     /locus_tag="KR231_001335"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:349..351,aa:Gly,seq:gcc)
     gene            416..492
                     /locus_tag="KR231_001336"
     tRNA            416..492
                     /locus_tag="KR231_001336"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:450..452,aa:Arg,seq:tct)
     gene            502..577
                     /locus_tag="KR231_001337"
     tRNA            502..577
                     /locus_tag="KR231_001337"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:535..537,aa:Gln,seq:ttg)
     gene            586..661
                     /locus_tag="KR231_001338"
     tRNA            586..661
                     /locus_tag="KR231_001338"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:619..621,aa:Lys,seq:ttt)
     gene            664..752
                     /locus_tag="KR231_001339"
     tRNA            664..752
                     /locus_tag="KR231_001339"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:698..700,aa:Ser,seq:tga)
     gene            756..831
                     /locus_tag="KR231_001340"
     tRNA            756..831
                     /locus_tag="KR231_001340"
                     /product="tRNA-Phe"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:789..791,aa:Phe,seq:gaa)
     gene            838..911
                     /locus_tag="KR231_001341"
     tRNA            838..911
                     /locus_tag="KR231_001341"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:872..874,aa:Met,seq:cat)
     gene            926..1002
                     /locus_tag="KR231_001342"
     tRNA            926..1002
                     /locus_tag="KR231_001342"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:960..962,aa:Ile,seq:cat)
     gene            1020..1096
                     /locus_tag="KR231_001343"
     tRNA            1020..1096
                     /locus_tag="KR231_001343"
                     /product="tRNA-His"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1054..1056,aa:His,seq:gtg)
     gene            1105..1180
                     /locus_tag="KR231_001344"
     tRNA            1105..1180
                     /locus_tag="KR231_001344"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1138..1140,aa:Lys,seq:ttt)
     gene            1188..1261
                     /locus_tag="KR231_001345"
     tRNA            1188..1261
                     /locus_tag="KR231_001345"
                     /product="tRNA-Cys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1220..1222,aa:Cys,seq:gca)
     gene            1269..1345
                     /locus_tag="KR231_001346"
     tRNA            1269..1345
                     /locus_tag="KR231_001346"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1303..1305,aa:Arg,seq:acg)
     gene            1358..1433
                     /locus_tag="KR231_001347"
     tRNA            1358..1433
                     /locus_tag="KR231_001347"
                     /product="tRNA-Val"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1391..1393,aa:Val,seq:tac)
     gene            1509..1922
                     /locus_tag="KR231_001348"
     CDS             1509..1922
                     /locus_tag="KR231_001348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009887782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0003732.1"
                     /translation="MYIVIGNEIVDSEELKIIIDKNSEFKVEKDLSKSTKREDVIAYQ
                     LSIDLNYLDSLINEQCNLASLSDEEKFDEYMTLSDELALDLEELMPKYTIINARAYKL
                     DEVDGIVKIILAVAYADLGHLKLSDVVKRLSRQVD"
     gene            2231..5662
                     /locus_tag="KR231_001349"
     CDS             2231..5662
                     /locus_tag="KR231_001349"
                     /EC_number="6.4.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate carboxylase"
                     /protein_id="HBH0003733.1"
                     /translation="MLKKFNKILVANRGEIAIRIFRACSELGIKSVGIYSKEDKYGLF
                     RTKADESYLIGEGKGPIDAYLDMDGIIDLAKRKKVDAIHPGYGFLAENAEFARKCEEN
                     GITFIGPSSKVMNMMGDKINSKKIAKEVNVQTIPGVEKAIRSTEEAKEVANKIGYPVM
                     IKASNGGGGRGMRIVHREEDLELEYETACSESRKAFGEDIIFIEKYIADPKHIEVQIL
                     GDNYGNIVHLYERDCSVQRRHQKIIEYAPAFSLDDKVRKEICEDAVKLSKHVGYSNAG
                     TLEFLVDANGGHYFIEMNTRVQVEHTVTEMVTGIDIVQSQILIAQGYSLDSEEINIKS
                     QDDVEIRGYSIQCRITTEDPKNKFMPDTGKIQVYRTGSGFGIRLDGGNGFTGANISPH
                     YDSLLVKTISWDRTFQGAINKTIRSIKELRVRGVKTNVGFLVNVLNNPIFSNGKCSTK
                     FIDENPDLFEITESKDRGTKLLQFIGDVIVNDNACKEKPLFDALHDPRMDKDGSKSEG
                     SKILFDKLGKSAYIEKIKNDKKLLLTDTTMRDAHQSLLATRIRTYDLLKAAKPTEKYQ
                     KDLFSLEMWGGATYDVAYRFLKESPWRRLQKLREEIPSIMFQMLLRASNGVGYKNYPD
                     NVIEEFTKESARQGIDVFRIFDSLNWVENMKPSINTALETGKIVEATMCYTGDILDKT
                     KTKYNLEYYIKMAQELESLGADIIAIKDMSGLLKPYSAYTLVKELKKNVKAPIHLHTH
                     DTSGNGVATCLMASEAGVDIIDAALESMAGLTSQPSLNAIVEALKNTERDTGIDLFGY
                     DELGKYYKDLRKVYNKFESDLTNSCAEIYNFEIPGGQYTNLKPQADSLGLVNRFDEVK
                     EKYKEANEVVGDIIKVTPSSKVVGDLAIFMTKNKLDKDNIIEEGKNLSFPDSVVDYCK
                     GMIGQPEGGIPKDLQEVVLKGEEAITVRPGSLLPAEDFDEIAKYLNEKYDINANIRNV
                     ISYALYPKVYEDYIKHLQHYNDISKLESDVFFYGLNKNEECEVEIEEGKVLTIRLVEI
                     GEVKENGFRTIGFELNGMVREVEIKDKNFSGKINNVEKADMNDPLQIGASIPGKVIKI
                     MVKEEDEVKANQPLIVIEAMKMETIIVAKTDGVIKSIKVKEDDMVEDKQLLMIMK"
     gene            5904..7832
                     /locus_tag="KR231_001350"
     CDS             5904..7832
                     /locus_tag="KR231_001350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009904742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor G"
                     /protein_id="HBH0003734.1"
                     /translation="MKVYDSKMLRNVAVLGHSGCGKTNLIETIAYTANTNKIPKLTDK
                     VNMTYSMGLIPIEYNDYKFNLLDTPGYFDFSGDVVSSLRASDAAIIVIDATAPIQVGT
                     EKSLELTESIPKIMFINKIDNEKARYKDAIAMLREKYNNKIVPMISPIYKDKNFVKLH
                     NVFENIDDLEGEFKEQAMSVKEALMELIAETDDQILDKYFNGEELTTEEIQKGIIIGI
                     QRGDIIPVICGSTINNIGTKEILDTISSYLEPIFTEESKPFRGLVFKTMVDPFVGKMS
                     YIKITEGVLSKDKDVFNINKNVKEKIANIYTLRNSELVEIEKAKAGDIVVITKVNSLK
                     TGDTISADKDAEALEKIDFPKPQIYYAVTPKNKGDEEKVASVLNKLVEEDPTLHWYRN
                     TETKQALLGGQGELHIKTIKNKMKDKFGVDVELNDLKVPYRETIKGTADVQGKHKKQS
                     GGHGQYGDVKIRFERCESDFEFTEEIFGGSVPKQYIPAVEKGLKDSMQKGILAGYPVT
                     NIKATLYDGSYHDVDSSEMAFKMAASAAFKKGMEEAHPILLEPIMKLKITVPEEYMGD
                     VMGDINKRRGKIFGMEPDDKGKQIIFAEAPQAETFKYAIDLRAMTQGRGYFEMELERY
                     GEVPSQFAEKIIGLATAK"
     gene            8285..8749
                     /locus_tag="KR231_001351"
     CDS             8285..8749
                     /locus_tag="KR231_001351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CtsR family transcriptional regulator"
                     /protein_id="HBH0003735.1"
                     /translation="MATMTDIIEKFIKDLMEEDNSIQIQRNELANLFSCAPSQINYVL
                     TTRFTIDRGYYIESKKGGGGYVQIEKIRKSKDGHIRELLNEKIGSQISYKKAKELLEG
                     LKESDLINERELKLILYAIDDKSLCMPIYELKEKVRSNILKNIIIGLFSIEE"
     gene            8756..9250
                     /locus_tag="KR231_001352"
     CDS             8756..9250
                     /locus_tag="KR231_001352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UvrB/UvrC motif-containing protein"
                     /protein_id="HBH0003736.1"
                     /translation="MLCQKCNKNKASVYYNKIVNGEKTEMYLCSECAKENTEMNFNLD
                     MPFSMMDIFSNLGFQPKKELEEKLVCPKCNTTYSEFKNNGRFGCSECYNAFSSQVNPM
                     LQNIHGHIEHTGKAPKKSFYKISVENEIKELKEDLDRAIKNEEYELAAQFRDKIKYLK
                     GSID"
     gene            9266..10291
                     /locus_tag="KR231_001353"
     CDS             9266..10291
                     /locus_tag="KR231_001353"
                     /EC_number="2.7.14.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein arginine kinase"
                     /protein_id="HBH0003737.1"
                     /translation="MKENIVMKSRVRLARNLNNYPFPNKLDKECAMEIIEKVKNAFIN
                     SNLEQKEEFDFYKIEDLDQSKKMLMVEEHIISPDLAENDKSAVIVKKDKTISIMINEE
                     DHIRIQTICDDLNLEYAYSVANEIDDLLESSLEYAFNTKLGYLTSCPTNTGTGMRASV
                     MMHLPALSQLGYMDELYKISSQIGIAIRGIYGERTEALGNIYQISNQLTLGRTESNII
                     ENVSGLTKDAISKEIKAREILQKKLGIKLEDKIFRSIGTLENSRVMSSAEAMSHLSNI
                     KMGIEMNYIDKLDLRAIEQLMIGIQPAHQSIMYKSDDVENRDINRATYIRETLEKLRG
                     GMNCELQ"
     gene            10278..12725
                     /locus_tag="KR231_001354"
     CDS             10278..12725
                     /locus_tag="KR231_001354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HBH0003738.1"
                     /translation="MNFNRFTQRAKKAIDLAFESAKSLGHNIVGSEHILLGLLREEEG
                     IAAKVLSKVGFTEAYLEGKIVDMEGKGEEISEDIVLSPRSKQILELSGMFANKLKTNY
                     IGTEHILLAIIQEGEGIANKILNYAGVNDRTLAQLTIDMMGISDKNQYKAENSYTGNQ
                     NQAESKVLDKYGRNLTLYAKQNKIDPVIGREKEIQRVIQILSRRTKNNPVLIGDPGVG
                     KTAIAEGLATNIALGNVPETLKNKTLYSLEMGSLLAGAKYRGEFEERIKEVVDEVVKN
                     GNIILFIDEMHTIIGAGSTGEGSIDASNILKPALARGEIQVIGATTIDEYRKHVEKDS
                     ALERRFQPVMVDEPTKEDSIKILEGLRDKYEAHHKVKITDDAIKAAVELSTRYISDRY
                     LPDKAIDLIDEAASKVRLKENTPPSEIKKLELEIENIDKEKEEAVRCQDFEKAAKIRD
                     EQGLLKKQLEDVRERWNKSSKHSDLVDGEVIAEVVGLWTGIPVNKILEEEADRLLRLE
                     EILHNRVIGQEQAVKSISKAIRRSRAGLKDPNRPIGSFLFLGPTGVGKTELSKALAEV
                     QFGDENQIIRIDMSEYMEKHAVSRMIGSPPGYVGHDEGGQLTEKVRRNPYSVILFDEI
                     EKAHPDVFNILLQILDDGRLTDSKGRTVDFKNTIVIMTSNVGASTIGRQKTLGFSIAK
                     GDEEEKSQYEKMKENIMGELKQRFRPEFLNRIDDIIVFHSLNENHISKIVLLMAAKLQ
                     ERLKEMDIKLEMSDEAVKLISKSGFDLEYGARPLKRALQKELEDELSEAILKGNVKKG
                     SNVVAKVKDEKIVFETK"
     gene            12905..14278
                     /gene="radA"
                     /locus_tag="KR231_001355"
     CDS             12905..14278
                     /gene="radA"
                     /locus_tag="KR231_001355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadA"
                     /protein_id="HBH0003739.1"
                     /translation="MAKIKTKYVCQSCGYETAKWLGKCPECTKWNTFVEEIDQKSTKK
                     EVFIIDKSSSKPVSINSIESKEEERFTTDINELDRVLGGGIVKGSLVLVGGDPGIGKS
                     TLLIQVSSNVANLGKTVLYITGEESESQIKMRAKRLGINSENLYIFAENNLSIIESYL
                     ESVNPELIILDSIQTVFSPEISSAPGTVSQIKEGTSKFMKISKKMGISTFIVGHVTKE
                     GSLAGPKLLEHMVDTVLYFEGERYNTYRLVRAVKNRFGSTNELGVFEMRDLGLVELDN
                     PSKILISEKPKDVAGSVIISTVEGTRPMLLELQALVSPTSFGIPKRTSTGVDYNRVGM
                     LLAVLEKRVGLQIQNQDVYINIVGGIKINEPSIDLGIAISVASSFRNIPIDEDIAVTG
                     EVGLTGEVRAVSFIEKRIAECKKLGFKKIVVPRSNYDVVKETKGIEIWPVDNLRQAIN
                     IVLGRNQ"
     gene            14281..15351
                     /gene="disA"
                     /locus_tag="KR231_001356"
     CDS             14281..15351
                     /gene="disA"
                     /locus_tag="KR231_001356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA integrity scanning protein DisA"
                     /protein_id="HBH0003740.1"
                     /translation="MENFLDNKNMLYALKMISPGTPLRLGLNNVLRAKTGGLIVIATN
                     EDVMKIVDGGFAINAEYSPSYLYELAKMDGAIVLSGDVKKILFANAQLIPDYFIETSE
                     TGTRHRTAERVAKQTGAIVIGISQRRNVITVYRGNEKYVVEDISKIFTKANQAIQTLE
                     KYKTVLDQAVTNLNALEFNDLVTIYDVALVMQKMEMVMRVTSIIEKYVIELGDEGTLV
                     SMQLEELMGTTRIDQKLIFKDYNKENTEIKELMKKVKNLNSEELIELVNMAKLLGYSG
                     FSESMDMPIKTRGYRILSKIHRLPTAIIENLVNYFENFQQILDASIEELDEVEGIGEI
                     RATYIKNGLIKMKQLVLLDRHI"
     gene            15440..16534
                     /locus_tag="KR231_001357"
     CDS             15440..16534
                     /locus_tag="KR231_001357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PIN/TRAM domain-containing protein"
                     /protein_id="HBH0003741.1"
                     /translation="MIRKVTRILFILLGFTIGITTYLTLMKDFEILTFGKETYGYIAA
                     VVAGIIIAILGYLIEPWVVNKVKEIAKIVDKELSKYPQTDILLGSMGLIVGFVIAYLL
                     SGLVNRIPIVGGILSLLLYLFLGYLGMKVALKSKNDLFNIGKLGRLANPIKDKDKDKE
                     NKKEVKAIPPKVLDTSVIIDGRIADICKTGFIEGKLIIPAFVLEELRHIADSSDDLKR
                     VRGRRGLDILNIIQKELNIEVEISERDFDDIAEVDSKLLKLAQVLNGKVVTNDYNLNK
                     VAQFQGVEVLNINELANAIKPVAIPGEDMVVQVVKEGKEAQQGVAYLDDGTMIVVDGG
                     RKYMNETIKVLVTSVLQTPAGRMIFAKPKN"
     gene            16663..18840
                     /locus_tag="KR231_001358"
     CDS             16663..18840
                     /locus_tag="KR231_001358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0003742.1"
                     /translation="MRKKIISFLATFIIILTSASQYSFADDISTRGKVIFIDMNRTSM
                     SNMLRIKSLREELDNRGYIGLMNIRGDKGSDDRRSYASMGAGGRANVANEEDINFESS
                     SKDRNIVFESATGKSAKGINNLTINKSINENLNFGEYGSVLGSLGQSLSDNGLKASVL
                     GNSDIIENGQLIKNRNLCLTAMDEYGRIPNGNVDTINKKDLSMPYGISTDYDKLIVET
                     KETYKNNDVIFVELGDTYRLDLYKPNLNEKTYESMKDNIEKNIDIYLKNIFSMVEEND
                     TIYIASAFPSDLDYKNKRRLSPIIKLNGEGKGILSSSTTRREGIVTNLDVGVEILDNF
                     NIKNQNMVGRKYELINRDDNKEFLMDEYQKIVSISSIRSTILNGFVSIVFLSWIVAMI
                     AILFRKHISKNYKETTFFILKELLKIGIVMPLSFMITPIMNFKTPLAISLGIIIITLT
                     IYLISKVLIKNDLKNMLFFTGLTIVIMVIDAGFGSYLMKSNVMSYDCIIGARYYGVGN
                     EYQGVAIGSAIFTFAILLTYKNIPKWYIIVFSLVILITSASPIMGANVGSAISECVAF
                     LLFILLIYNVKIDFKKIVLLGIAVVFVLGVFVAIDMILGSNSHLGMFVKEIYFNGPGE
                     IIQTFSRKIEMNLKLAQTSAWVNILLTGIGVILVLMINQIRYFKQLMDEYPIVFKGFI
                     ASIAGCLVTLLVNDSGIVSSATAFIYVIVPMITLSINLTALKE"
     gene            complement(19026..19871)
                     /locus_tag="KR231_001359"
     CDS             complement(19026..19871)
                     /locus_tag="KR231_001359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBH0003743.1"
                     /translation="MNRNNFSHEIIEPIDNLDVNFKLFDDSGSYVANHWHNSLEIIYI
                     TSGDLQINMEGYTYNLKANECMFINSGIIHSTRCIYQNTSILLQVPLSFLNKYIPDFK
                     NCYFDFKVNANDNNYKKNSSKVKLILENMREIKLSSPPAANLLFTSLLFELLFELYTN
                     FKISVGNKNMKKTVLDLSKFEPVLEYTKINYKMPISINKIAKVAHLQPEYFCRKFKQY
                     MGQTYLEYLNDVRISHIYKDLINTNDTLCSILEAHGFTNTKLFYRIFKEKFKCTPKHI
                     RKKST"
     gene            20088..21254
                     /locus_tag="KR231_001360"
     CDS             20088..21254
                     /locus_tag="KR231_001360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009887803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cellulase family glycosylhydrolase"
                     /protein_id="HBH0003744.1"
                     /translation="MYIKGVNLGGWLVLEKWMTSSLFEGTEAEDEYYLPRQLSREAYE
                     SRIKTHRSEYITERDFATIKSMGFNSVRIPVPYFIFGDCEPFIGCVKELDKAFAWADK
                     YGLSILIDLHTVPGSQNGFDNGGISGICSWSQNPEYVAFTLNVLERLAKRYGMRHELY
                     GIQILNEPITERMWNIMNVPNRFKAVDKEMARGSKPNSLEFLRDFYIKAYRVMRPYMR
                     EENVIVFHDAFELKAWKDFMREEEFKNVVLDTHQYLMLAEADGCEQSIDSYLKYIREN
                     YAKDILQMQKYFPVICGEWSLFNSYVCGIDTNGGQSPLNGIESNIDKLSKDDKRELYR
                     KIAKAQLDAWRNGSGHYYWNYKLLLDTVNEEGWIGWDSWDLGKCVAQEWYPIEY"
     gene            21276..22922
                     /locus_tag="KR231_001361"
     CDS             21276..22922
                     /locus_tag="KR231_001361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453968.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 43 protein"
                     /protein_id="HBH0003745.1"
                     /translation="MIKNPILPGFNPDPCICRKGDDYYLVVSSFEWFPGIPVYHSKDL
                     KNWELYTHILTDETKIDLKKLPSSKGIWAPCLTYCEEEDLFYIVYGIMNSMNARYFDV
                     DNYLITSKDIKGEWSEPVYLHSSGFDASIFHDDDGKKWIASLDWETREGYEKPGVICL
                     VEYCTKKKEIVGYPKRIWSGGTDRGCIEAPHITKRGDYYYIMCAEGGTGYGHSVTMGR
                     AKNIWGPYEKDSMNPIVTSIPGDFYERHDPDHLKPKYYNPESKLQKSGHGSYIETTSG
                     EVYLVHLTSRPFVPELRCTLGRETAIQKMKWTKDNWLRMEDESNLAKEYVSESKLEEH
                     LVSSIPSFDDFDSNELGLQYYAPRISPLSFADVKSRPGYVRIRGQESRTSLNKVSILA
                     RKLTSVYARITTKMEFYPEVHQHSAGLIMYYDNMNYINLRKYYSETLGQSALSIIHLE
                     NGEKTEFLNTRIPIKDIPIYLRLYIQGRKSYFEWSYDEKNYQRIGKVFDTTKFSDEYC
                     KYGEFTGTFIGLTCADRVKHKHYADFDFFEYIVDESKDVD"
     gene            23019..24392
                     /locus_tag="KR231_001362"
     CDS             23019..24392
                     /locus_tag="KR231_001362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBH0003746.1"
                     /translation="MNTEVNVKATTIRYEKISFFERISYGCGDLGCNIIYSAMSAFLL
                     FYYTNYADVSAAAVGSIMLVSRILDGFSDLTMGIIVDRTKSKYGKARPWILRMAIPFA
                     IAAVLLFSVPSNLGITSKLIYIFITYNLVSTVIYTAINVPYATLNSLITQNQYERGVL
                     SIFRMILATCDTLLINGLTLPLVEYFGNNLSAWTKTFFVFGIASIMVFFITFTGTKER
                     VKAVKQDRNEVIPFKIGIKSLFRNKYWIQITLCLVCIFIVFAINGGSSVYYAKFILGD
                     EKLFGPINMVSNISQIIAMFMVAPFIKKFGKRNVLIVGSIILISSNVMFIIVGQNHIG
                     VIFASAIKGIGSAGIASTMFAIVSDTIEYGEWKTGYRTEGLINSASSFGFKVGNGLGS
                     AILGAVLSIGGYVGTSATQSDLAIVSIKVCFIYLPIFITILQIIIMSFYKLDKEYSTI
                     LNELNTK"
     gene            24837..25790
                     /locus_tag="KR231_001363"
     CDS             24837..25790
                     /locus_tag="KR231_001363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009904745.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-binding transcriptional regulator"
                     /protein_id="HBH0003747.1"
                     /translation="MKKIGDLRLMMKCCSLYYEDNLNQQEIANQLGISRPTISRILKE
                     AFEQGIVKIQIVDVLKNDYQKIERSLERKYKLKEVIVVDDKQDALTQKQELARAVSEY
                     LTRVVKENDIIGVSIGTTLKEIPRYVEKSNCKNVTFIPLLGGIGDNEIDIHANQIAVS
                     LARAFGGDFKLLHAPAVMSDLSTKEKLCKDEKIKEVLDLIDKTTIAIVGIGNPMSLNS
                     TIMASGYMNEADIEDLKKYNSIGAICLQAFDKEGKTSILEFNQRVLGVKLEDLKKIKR
                     TIGVASGDEKIEAIKASLKAKFINSLAINHSLALKLLEDCD"
     gene            25828..26790
                     /locus_tag="KR231_001364"
     CDS             25828..26790
                     /locus_tag="KR231_001364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009887810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine pyrophosphate-dependent dehydrogenase
                     E1 component subunit alpha"
                     /protein_id="HBH0003748.1"
                     /translation="MSISKETLLEMYKRMNQARKFEEKVSWFFARGMVHGTTHLSVGQ
                     EASSVAAVMALEKGDLVSLTHRGHSQFIGMGIDLNKMMAELMGKETGFCKGKGGSMHI
                     ADIESGNLGANGVVGGGLTIAPGAALTQQYKKTGKIVLCSFGDGASNEGTFHEGINLS
                     SIWKLPIIFYCENNLYGMSTSIKRHMNIESIATRAASYGIEGISIDGYNPIEVYETVQ
                     KAAEKCRRGEGPVLIESRTYRWLGHSKSDANVYRTKEEIESWKAKDPIEFLKNYLIEN
                     NLSNEDELDKIQEFAKQSIEDAVEFAQNSPNPKIESLLEDVYAD"
     gene            26815..27801
                     /locus_tag="KR231_001365"
     CDS             26815..27801
                     /locus_tag="KR231_001365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-ketoacid dehydrogenase subunit beta"
                     /protein_id="HBH0003749.1"
                     /translation="MSTRELTYAQAIKEAMSEEMRRDENVIFMGEDIGIYGGAFGVSV
                     GMIDEFGPERVRDTPISEAAIAGAAAGAAATGLRPIMEVMFMDFVTISMDAIVNQAAK
                     MRYMFGGKAQVPMVVRCPGGSGTGSAEQHSQSLEAWFCHVPGVKVVAPSTPADAKGLL
                     KAAIRDNNPVIFVENKLLYRKKGFVPEDDYVIEIGKADIKREGTDVTVITYGRMLQSV
                     EEAAETLSKENINVEIIDLRTLYPLDKETIVKSVCKTGRVLICHEAAKTGGLGGEISA
                     LITESESFDYLDAPVKRICGKDVPIPYNPELEKAVVPRVDEIEEAIKSLIVR"
     gene            27814..28860
                     /locus_tag="KR231_001366"
     CDS             27814..28860
                     /locus_tag="KR231_001366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895167.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-oxo acid dehydrogenase subunit E2"
                     /protein_id="HBH0003750.1"
                     /translation="MVANKIKATPAARSQARKDNIKLDRLIGSGENGRIHLVDVLNYL
                     KDNKANTTPLARRIAEDLNIDLETIVGTGYNGKIRKCDVEKLTGKETIVSTNTSKSSE
                     KKELKIENENSRMFNTVEGIFEKPNPMRATVAKRMSESYFSAPVFTFNIEVDATELKV
                     LRAKLIDTVKESTGVKLTMTDLIVMAVSKILPNHQALNSAWTDEGIFRYKDVNIAIAV
                     GLDEGLYVPVVKNANKKSLKEIAKESKELAEKVKTGKLMPADQEGNTFTISNVGMYGI
                     TTFTPIINMPSSAILGVGATQDKFVPVNGEAKIKPIMNLSLTSDHRVIDGTVAAKFLK
                     DLKELLENPLSMLV"
     gene            29027..30757
                     /gene="lpdA"
                     /locus_tag="KR231_001367"
     CDS             29027..30757
                     /gene="lpdA"
                     /locus_tag="KR231_001367"
                     /EC_number="1.8.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoyl dehydrogenase"
                     /protein_id="HBH0003751.1"
                     /translation="MSVEVIMPKAGVAMEEGTIVSWLKQEGEEVKIGEPILEITTDKV
                     NMEIESEGEGTLAVIIHKEEGEVLPVFTVIGVIAEKGENQEEVKAKYLSGNVSKEDIV
                     EENQNIEFKEEKINKKECNHDYDVVVIGGGPGGYLSALKAALLGGRVALVEENILGGT
                     CLNRGCIPTKTYIKTAEILEEIDQLSKRGVKVTVDKEQDIKKAIKYKNRVVKKLTAGV
                     GGLLKSRDVDVFNLKASVKEEHKVILSDGKVLDTENIIIATGSKVRILPIKGIESNLI
                     ITSTEALDLETVPEELVIIGGGVIGCEFAEIFNSRGSKVTIVEMEDRVIPRMDKELSE
                     SLKYSLSKKGINVLTKKKVSEFKEEGNNILVCIEGEEPIKADLCLYAIGREANLSGIE
                     DLDIKIDKGSIVVNSKMETSIPSIYAVGDVTGGVMLAHAAFKMGEVAASNALGVNKEV
                     DLGALPSCVYTIPEVASVGITEEDARKKYNVKVGKFNFAGNGRALASGQEQGYVKVVA
                     DAKYGEILGIHMFGCGVAELINHAASFKALEIPTDEASELIFGHPCTSEALMEALADV
                     NGECLHLPKK"
     gene            31175..34123
                     /locus_tag="KR231_001368"
     CDS             31175..34123
                     /locus_tag="KR231_001368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009887817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HBH0003752.1"
                     /translation="MRQRIKNLIENEDKKNPLTDEAISSRLNIRREDVTFLRNELKIE
                     DSRQRRKVVLIKAIKDILKEEKTINKNDITRRLNSIGFTVSRFTVIQYLKEIQDSGDL
                     KLDKESDDKKEEIINNRENKDIAFDKLIGSSGSLSTIIKLAKAAILYPPHGLHTIIMG
                     PTGVGKSELAECMYKFAVESSRFPKNAPFIVFNAADYSENPQLLLSQLFGHVKGAFTG
                     ADENKEGLVSKADGGILFIDEIHRLPHEGQEILFQLIDKGMVRKLGETRLTHKIDVMI
                     ISATSEPIDSHLLNTFKRRIPVTIEIPELVARPLNERFDIINNFFLIEAQRMGANIHI
                     KSDVLKALMLYDCIGNVGQLRSDIQVACARGLLNQLTNKLKEVNISISDVPGYVKQGL
                     IKIRNCRGKIENYVDGDLIIDSNLQGEIEKKNEDIYTFPDEIYKLTERRHIDLLEQGL
                     DFDVINRIIGGELESCIQKYIKQVKKVSISNNLPDISPIVGKYIVELTYEVIKIASQY
                     LSSLEPNLHLCLAVHLKAAFERLKEGKVISNAHLKEIIGNYPVEYSVAEKVAQYLKER
                     YNINLPKEEIGIIAIYFKMSSRRDMSEQKKIGVLLMAHGRVASSVCEVTNKLLGINHA
                     RYLDMPFEKKPEEMIEEATTIIKDIDEGRGVIILVDMGSLSYFGDIISGKTGINIRTI
                     SRFDTLLSIEVIRRAVLPDLTIDEIVDEVKGIEPQVKEKVSKCNNTKVDFRKPIILTL
                     CITGLGGACKIKKILEENIKSITEKVDIEPIGMIEYPSLDLEIKQISNDKNVIAIVGT
                     IDPQIANIPFFSLVDINDKAKLNQINNLIDTNQIGETNKKYELSDLIHKEDIFVDLQV
                     KSKEEVLKYMSKKLREKGYVTKNFYKKVVERDNLFPTELSDEIAIPHTDGIDVIRPAI
                     SIAILKKPIVWSKSKVKIILLLAVDQKCFNPLSTLLSFIETDEFKKIKNIKDRDFIRE
                     MILDGVNENN"
     gene            34101..34565
                     /locus_tag="KR231_001369"
     CDS             34101..34565
                     /locus_tag="KR231_001369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBH0003753.1"
                     /translation="MESMKIISSNLIFKNIEVSNNEDALKFLGQRLFDEQYVKESYIQ
                     AVVAREKKYATGLPTEIYGVAIPHTDIVHVNEPGIAIGILNKPVKFIMMGTDDTEIDV
                     KVVFMLAVKEPQEQLQLLEKLMTIFQDKNILNNIVDLSEESVSDLLNSKLKN"
     gene            34678..34980
                     /locus_tag="KR231_001370"
     CDS             34678..34980
                     /locus_tag="KR231_001370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBH0003754.1"
                     /translation="MGVTNVAKKILVACGTGVCTSTIAINKLKKALQDIGKLDMVNIT
                     QCKVVEVASKAPDYDLIICTTQVSSSIKTPVINGLPFLTGVGMDKLINDVLEELEL"
     gene            35042..36406
                     /locus_tag="KR231_001371"
     CDS             35042..36406
                     /locus_tag="KR231_001371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425524.1"
                     /note="with GatAB forms a phosphoenolpyruvate-dependent
                     sugar phosphotransferase transporter for galactitol;
                     subunit IIC forms the translocation channel and contains
                     the substrate binding site; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS galactitol transporter subunit IIC"
                     /protein_id="HBH0003755.1"
                     /translation="MEGLYMEILNFIVGLGAQVMMPIIICIFGLILGTKLGKSLRAGL
                     TVGVGFIGLNTIIALLTDNLGPATQQMVKNLGLSLSIIDVGWPAASAIAFASTVGALI
                     IPIGLVVNIVMLITNTTQTVDVDIWDYWHFAFTGALVAGATQSVMWGVFASVANMVIV
                     LVMADLTAPGIEEYLGMPGISLPHGFTQAFVPIAIVVNKLLDLIPGINKIEINADTLQ
                     KKFGLFGEPLIMGSVIGVIIGIAAKYDIKGILQLGVTMGAVLILIPKMAALLMEGLLP
                     VSEAAQEFIEKRFKNRGKIYIGLDSAVGIGHPVTLSVALVLVPLTILIAAILPGNKVL
                     PFADLAVIPFALVLIVPITKGNVFRTLIIGIIIITSGLLIATNLAPLFTQMALNASFK
                     MPEGATMISSICDGANPLSWVFVKVMNYKVIGGVVFGVIALGMAIYNRNRIINENKKL
                     SIEE"
     gene            36441..36914
                     /locus_tag="KR231_001372"
     CDS             36441..36914
                     /locus_tag="KR231_001372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0003756.1"
                     /translation="MKKYKYDSKRYLLSVTIPGFFMILILIYALFNNYTNFNLNIYSL
                     LIIVCTYGIFNTFISSSNPKKIIIDSKCIHFTSFMTTHKYEIKDIEKIRIREFYNKKI
                     YVKINDGNLFKGRYWIRTNMFNNSIALYSYFIELEECLYPDSLKFRNKKFENKNI"
     gene            37086..37736
                     /locus_tag="KR231_001373"
     CDS             37086..37736
                     /locus_tag="KR231_001373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class II aldolase/adducin family protein"
                     /protein_id="HBH0003757.1"
                     /translation="MLLEKLRKEVLQASLDLLNYNLVTLTGGNVSGRDEQTGYIAITP
                     SGMDYRNLTPSDIVIVDVDGNIIDGKWKASVDLSDHLYIYKHREDINSIIHTHSTYSS
                     CFAILNEPIECASTTLANEVGGSVPVAKFSPPTSKKMGKCVIEAIGDKRACLLANHGV
                     IAVGPSVGHALTAAVMLEDSAKVYYLAKSIGTPVLLPDEEIQRARDVFFNVYGQDK"
     gene            37910..38842
                     /locus_tag="KR231_001374"
     CDS             37910..38842
                     /locus_tag="KR231_001374"
                     /EC_number="6.3.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate--protein ligase"
                     /protein_id="HBH0003758.1"
                     /translation="MYYLLNKSTNPYFNLALEEYLFLNDKYNDDIIIIWRNEESIFIG
                     KNQNPYQEVYHDVIEKGEIPILRRISGGGTVYHDLGNINMSFIQKDRQLHEIDFLEHT
                     KFMQKMLSTLGLDVSITERKDLFLNGKKISGSAQSIKRKNSLYHGTLLYDSDLNKLTK
                     YLNSNKATESNATKSVSSKVTNIKFLLEKDINYFLDYCVEYLKSNIKNIKELELDEED
                     IKSVYNIGEDKYKKIEWTYGKTPKFQVVLPFNNESKINIHVNRWKVSKFFISYDDNVI
                     NMDKLLDLNFFKEEIKESILENYPHYIDLINLIF"
     gene            39116..39829
                     /gene="ispD"
                     /locus_tag="KR231_001375"
     CDS             39116..39829
                     /gene="ispD"
                     /locus_tag="KR231_001375"
                     /EC_number="2.7.7.60"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009904750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-C-methyl-D-erythritol 4-phosphate
                     cytidylyltransferase"
                     /protein_id="HBH0003759.1"
                     /translation="MYSVIIVAAGSGRRMNLDINKQFIKLREKEIIAHTIQVFYENIN
                     IDEIVVCIKKEEEDFFKENIINKYNFKNIKIAYGGKERQDSIYNGLKKLDENCDIVLI
                     HDGARPFVDHRIINESIKVAKEKKAVVVGVPVSDTIKIVSDGTVQETPERNLLWAAQT
                     PQTFEYNLIIDAYEQAYKNNYYGTDDSMLVENIGQSVTMVMGSYENIKITSPEDLNIA
                     EQILNMEKRDEVNSRRRII"
     gene            39826..40311
                     /locus_tag="KR231_001376"
     CDS             39826..40311
                     /locus_tag="KR231_001376"
                     /EC_number="4.6.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009887828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-C-methyl-D-erythritol 2,4-cyclodiphosphate
                     synthase"
                     /protein_id="HBH0003760.1"
                     /translation="MRIGLGYDVHKLTEDRKLIIGGVEIPHDKGLLGHSDADVLIHAI
                     MDSILGALALGDIGKHFPDTDEEYKGADSMKLLEHVYNLITSKGYKIGNIDSTIIAQS
                     PKMAPYIESMRSNISKVLNTDIDNINIKATTEEGLGFTGAKQGIASQSICLLLLTSQN
                     N"
     misc_binding    40406..40614
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            40678..42393
                     /locus_tag="KR231_001377"
     CDS             40678..42393
                     /locus_tag="KR231_001377"
                     /EC_number="6.1.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proline--tRNA ligase"
                     /protein_id="HBH0003761.1"
                     /translation="MKMSKMFMPTLKEIPADAEITSHQLMVRSGMIKKMTSGVYNQLP
                     MGLRVFKKIEQIIREELNKKDCQEILCAALLPSELWKESGRWTAMGEEMFRLKDRTER
                     EYCLGPTHEEAFTDIIRQEITSYKQLPLNLYQIQVKYRDERRPRFGVMRTKTFTMKDA
                     YSFDVDDKGLDKSYQDMFDAYVSIFDRCGLENSPVQADSGAIGGSTSAEFMVKSEVGE
                     DEVVFCSGCDYAANVERAESCNLASQKEEMKELEEVHTPGAATIKELEEFLKTSPDKF
                     AKTLVYEADGKTVVVVVRGDREVNEIKVSNAIGSVIEFALATDDVVRKVTNAEVGFAG
                     PIGINADYVFIDKEIVEQRNIVVGANKTEYHIKNANYGRDFEGIVGDFRNVQEGDKCI
                     VCGKPLEIARGVEVGHIFKLGTKYSESMNANFIDKDGKSKPIVMGCYGIGVERTAAAI
                     IEQHNDEKGIIWPLSVAPYHVVIVPANMKNEEQISIAENIYNDLQAMGVEVLLDDRDE
                     RIGVKFNDSELIGIPMRITVGKNINEGKVEFKLRHKEDKEIIDIEEINEKVKAEFIRN
                     NVRLG"
     gene            42515..43960
                     /locus_tag="KR231_001378"
     CDS             42515..43960
                     /locus_tag="KR231_001378"
                     /EC_number="6.1.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proline--tRNA ligase"
                     /protein_id="HBH0003762.1"
                     /translation="MAKNEKQFVEEITKMEDDFPQWYTDVITKTDLVDYAPVKGFMVV
                     KPYGYALWEKMQEFMDKKFKETGHKNCYFPLLIPESLLNKEAEHVEGFAPEVAWVTHG
                     GNKKLEERLCVRPTSETIICTMYAKWLKSYRELPYLYNQWCSVVRWEKSTRPFLRTSE
                     FLWQEGHTLHETAEEAQEETIQQLEVYKALCEELLAMPVVAGQKSESEKFAGGERTYT
                     IEAMMHDGKALQSGTSHFLGQHFTKAFDITFADREGNLANPYHTSWGASTRLIGGLIM
                     THSDNRGLVLPPRVAPIQVVIVPIAAKKGNVMETVDKIYADLKAKGVAVEVDDRDNYT
                     TGWKFNEWEMKGVPVRVEIGPKDIENNQAMVFRRDTLEKDSMPLEGLADAICDLFDVI
                     HNDMFEKARKHREDNTSIVENMDEFRKALEEKPGFIKTMWCGDAECEAKIKEETGATI
                     RCLPFEQENLGHKCVYCGKEADSMVVMAKAY"
     gene            44400..45881
                     /locus_tag="KR231_001379"
     CDS             44400..45881
                     /locus_tag="KR231_001379"
                     /EC_number="6.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate--tRNA ligase"
                     /protein_id="HBH0003763.1"
                     /translation="MNVRVRFAPSPTGFVHIGSLRTALYNYLFAKKMGGEYILRVEDT
                     DQSRLVEGAIENMLNAMKWAGVNHSEGVILDDSGKVVQKGEYGPYIQSQRLDIYQEYI
                     KQLLDSGKAYYCFCTKERLDEVRDAQRAAGETAKYDGHCKNLSKEEVEANIKAGIPYV
                     IRLRLPENHTIKFTDLVRGDMEFNTNDLDDQVLMKTDGFPTYHFAVVVDDYLMKITHV
                     IRGEEWVSSTPKHVYLYEAFGWEAPVFVHLPNILNKEKKKLSKRQGDVAVEDFKKKGY
                     LPEGLVNYVALVGWSPEDNQELFTMEELEKAFSVERVSKSGGVFDTEKLNWVNQHYIK
                     DGDDAYLTDLAIPFLIEDGFITEEEATNKYDFLKSMISVLKEKLQYVKEVTEHASIFF
                     GDKIEVETEEGREFLRLEHIPTLIDALREKIEKTEVLNAEFVQAMLKEIQKEYKIKGK
                     NLFMGSRIILTGQMHGPDLPKVMEVLGKETCLNRIAYVKNNIL"
     gene            46102..46257
                     /locus_tag="KR231_001380"
     CDS             46102..46257
                     /locus_tag="KR231_001380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0003764.1"
                     /translation="MYSNIDDVKKELKELCLEYVTILEKLKDEKMITEETFEKCSSQK
                     KIFLEEQ"
     gene            46402..47799
                     /locus_tag="KR231_001381"
     CDS             46402..47799
                     /locus_tag="KR231_001381"
                     /EC_number="6.1.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine--tRNA ligase"
                     /protein_id="HBH0003765.1"
                     /translation="MKVYNTLTRTKEEFVPLEEGKVKMYVCGPTVYNYIHIGNARPFI
                     IFDTLRRYLEYRGYDVTYVQNFTDVDDKIINRSHEEGISPEEVAAKYIKEYFVDCDGL
                     GIKRATVHPQVTDNIQQIIEFIKELEDKGYAYAVNGDVYFDTNKFEGYGKLSGQKQED
                     LEAGARIEVNDQKRHPMDFVLWKAKKEGEPGWDSPWGEGRPGWHIECSVMSKRYLGET
                     IDIHAGGQDLTFPHHENEIAQSEARSGKTFSKYWMHNGYININDEKMSKSKGNFFTVR
                     DISKLYDLEIVRFFMLSAHYRNPVNFSDEMLNQAKAGLERLYNTKEKLEFTLSNLVES
                     PLTEKEVELVKELDDFRQKFIDAMDDDVNTADAVSVIFELAKLINSNVDENSSLEFAK
                     KCLDEFNELTGVLNIVNKKKDTVLDKDIEELIQKRTDAKKNKEFQLADDIRQQLLDMG
                     IVLEDTRQGVKWKRI"
     gene            47784..48197
                     /locus_tag="KR231_001382"
     CDS             47784..48197
                     /locus_tag="KR231_001382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mini-ribonuclease 3"
                     /protein_id="HBH0003766.1"
                     /translation="MEKDIKMEKTELVTMSPLVLAYLGDTVYETYIREYLIRQNTQRK
                     VNDLHKLAIKYVKAKAQATIIHEIEIELTEEESKIYKRGRNQKSNTSPKNADIIDYKH
                     ATGFEALVGYLYLNNEIERLQYIINKGIKIIERDM"
     gene            48303..49061
                     /locus_tag="KR231_001383"
     CDS             48303..49061
                     /locus_tag="KR231_001383"
                     /EC_number="2.1.1.148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent thymidylate synthase"
                     /protein_id="HBH0003767.1"
                     /translation="MKVKLISHTPEPEKVIAMAAKLCYSPVGTDEIEKDLTDESIEKF
                     LNMLLSIGHGSILEHASFTFSIEGISRACSHQIVRHRIASFSQQSQRYVKLEQFEYII
                     PPEIEKIEKAKELFIDSMKKDQENYDKLVEILFENHYNDLIKNGKNEKTAKRQAEKKA
                     IEDARYVFPNACETKMVFTINARSLFNFFEHRCCERAQWEIRNLAVEMLREVKKVAPI
                     LFKKTGPSCVNGSCPEGTMTCGDIVQVREKFKAL"
     gene            49074..49811
                     /gene="rlmB"
                     /locus_tag="KR231_001384"
     CDS             49074..49811
                     /gene="rlmB"
                     /locus_tag="KR231_001384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009887855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (guanosine(2251)-2'-O)-methyltransferase RlmB"
                     /protein_id="HBH0003768.1"
                     /translation="MASIEGRNPVIEAIKSDREIDKILIANSAKEGSIKKIIGMAKDK
                     NIIIQYVDKHKLDEVSTSHSHQGVIAYASEYKYYELDELIDLAKNKDEDPFFIILDEI
                     TDPHNLGSIIRTADAVGAHGVIIPKRRSVHITPVVAKASAGAVEYMPVCKVTNIVNTI
                     KRLKEEGLWIAAADMDGETFYKQNLTGPLGVVIGSEGFGISRLVKQNCDFIVKMPMIG
                     NVTSLNASVAGGILLYEIFRQRLDKSK"
     gene            49814..50341
                     /locus_tag="KR231_001385"
     CDS             49814..50341
                     /locus_tag="KR231_001385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NYN domain-containing protein"
                     /protein_id="HBH0003769.1"
                     /translation="MKKNINHYLIIDGYNIINAWDNLKELAKEDLEDSREKLIDDIIE
                     FSEFMGYKTIIVFDAYNVKNSREKVEKRKHITIVYTREHQTADSYIEKFITSLSKYDD
                     VKVATNDYAEQQMILGKGATRMSARELKLELDRSKNKMKEKNIGLRKKIQRNWLEERL
                     DKETLSKLENIRRKR"
     gene            50406..51053
                     /gene="sigH"
                     /locus_tag="KR231_001386"
     CDS             50406..51053
                     /gene="sigH"
                     /locus_tag="KR231_001386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sporulation sigma factor SigH"
                     /protein_id="HBH0003770.1"
                     /translation="MLVAKEKSYELVDNCQQDEYNIVLRASEGDKIALEYIITKYRNF
                     VKAKAKSYFLIGADKEDIIQEGMIGLYKAVRDFDGSKTNSFKCFAEICITRQIITAIK
                     TATRQKHIPLNSYVSLNKPIYDEESDRTLLDIIATSIVTDPEELIISKEELKNIESKM
                     NELLSDLELEVLELYLNGKSYQFIADKLKRDVKSIDNALQRVKRKLEKHLENRND"
     gene            51127..>51929
                     /locus_tag="KR231_001387"
     CDS             51127..>51929
                     /locus_tag="KR231_001387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009887863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HBH0003771.1"
                     /translation="MAKAKYERTKPHVNIGTIGHVDHGKTTLTAAITKTLYDRYQLGE
                     AVDFANIDKAPEERERGITISTAHVEYETPNRHYAHVDCPGHADYVKNMITGAAQMDG
                     AILVCSATDGPMPQTREHILLSRQVGVPYIVVFLNKCDMVDDEELLELVEMEVRDLLT
                     EYDFPGDDTPIVRGSALMALEDPKSEWGDKIVELFEQIDEYIPAPERDTDKPFLMPVE
                     DVFSITGRGTVATGRVERGVLKVQDEVELVGLTEAPRKVVVTGVEMFRK"
BASE COUNT        21135 a         5580 c         9860 g        15354 t
ORIGIN      
        1 ccccttccag gtcgccaaaa taaaatgctg gtgtggctca acggtagagc agctgacttg
       61 taatcagcag gttgtaggtt cgattcctat caccagctcc atataaaatt aatacggagg
      121 atttcccgag cggccaaagg gggcagactg taaatctgtt gtcatcgact tcggtggttc
      181 gaatccacca tcctccatca aaaaaatgcg cggatgtggc ggaattggca gacgcactag
      241 acttaggatc tagcgccatt ggcgtggggg ttcgactccc ttcatccgca ccatttttat
      301 ttaatttaat aaacgagcgg gaatagttca gtggtagagc gcaaccttgc caaggttgaa
      361 gtcgcgagtt cgaatctcgt ttcccgctcc aaattttatg tttatgttgt aatgtgggtg
      421 catagctcag ctggatagag caacgccctt ctaaggcgtg tgtccggggt tcgaatccct
      481 gtgcgctcac cacatatata ttggggatta gccaagtcgg taaggcacat gactttgact
      541 catgtatgcg taggttcgag tcctgcatcc ccagccaaac agtatggtct attagctcag
      601 tcggtagagc acctgacttt taatcagggt gtcccgcgtt cgagtcgcgg atagatcacc
      661 aatggagagg tgtccgagtg gtttaaggag ctggtcttga aaaccagtga cttcgaaagg
      721 ggccgtgggt tcgaatccca ccctctccgc caaatgccca gatagctcag tcggtagagc
      781 aggggactga aaatccccgt gtcggtggtt cgattccgcc tctgggcacc aaaatgtggc
      841 ggtatagctt agttggctag agcgttcggt tcatacccga aaggtcatag gttcgactcc
      901 tattaccgct actaaaattt aatgtgggcc attagctcag ttggttagag cgcccggctc
      961 ataaccggta ggtctggggt tcgagtccct gatggcccac cacattaaat taacttatgg
     1021 tgggtatagc tcagttggtt agagcgccag attgtggctc tggaggtcgt gagttcgact
     1081 ctcattatcc accccaactt atatggtcta ttagctcagt cggtagagca cctgactttt
     1141 aatcagggtg tcccgcgttc gagtcgcgga tagatcacca aaaaggcggc gacatagcca
     1201 agtggtaagg cagtggactg caactccttg atccccagtt cgaatctggg tgtcgcctcc
     1261 aataaaatgc gctcatagct caactggata gagtgtctga ctacgaatca gaaggttagg
     1321 ggttcgagtc cctttgggcg caccatatga atagcgaggg attatagctc agctgggaga
     1381 gcacctgcct tacaagcagg gggtcacagg ttcgagccct gttaatccca ccagtgcaaa
     1441 cctctagtaa aactactaga ggttttattt ttgattgaaa aagtttttat atttaggagg
     1501 taaaaaattt gtatatagta ataggaaatg aaatagttga tagtgaagaa cttaaaataa
     1561 ttatagataa aaatagtgaa tttaaagttg aaaaagattt aagtaaaagc acaaaaagag
     1621 aagatgtaat agcatatcag ttaagtatag atttaaatta cctagattct cttataaatg
     1681 agcaatgtaa tttagccagt ctatctgatg aagagaaatt tgatgaatat atgactttgt
     1741 ctgatgaact tgcactggat ttagaagagt taatgccaaa atatacaata ataaatgcta
     1801 gagcatataa attagacgag gtagatggaa ttgtaaaaat aatactagct gtagcgtatg
     1861 cagatttagg gcacttaaaa ctttctgatg tagtaaagag gctatctaga caagtagatt
     1921 aggatatgaa tatgaactat attaaaaaaa tgtataaaat cttacgtaaa gatgaaaata
     1981 attatgtaaa catagaaaaa aacagtataa aatcaagtca attgtagaaa ttttcacata
     2041 aattcatctg aaattctgta aaaaatgcct taattttaat gaggtaaatc gagtttacac
     2101 agtctaaaaa ttacttatat ttataaattt atcttattaa ttaaggaact ttcttaaaca
     2161 tcttcaaaaa taaagtattt tagtctataa tctttaatat tacacaaaca ataaaggaga
     2221 agaatagagt atgcttaaaa agtttaataa aatactagtg gctaatagag gcgaaatagc
     2281 tataagaata tttagagcct gttcagaatt ggggataaaa agtgttggta tatacagtaa
     2341 ggaagataag tatggattgt ttagaacaaa agcggatgaa tcatatttga taggagaagg
     2401 taaagggcca atagatgcat atttagatat ggatggaata atagacctag caaagagaaa
     2461 aaaagttgat gctatacatc caggatatgg ttttctagcg gagaatgcag aatttgctcg
     2521 taaatgtgaa gagaatggaa ttacttttat aggaccatca tctaaggtaa tgaatatgat
     2581 gggggataag attaactcta aaaaaatcgc aaaagaagtt aatgttcaaa ctataccagg
     2641 agtagaaaaa gcaataagaa gtactgaaga agcaaaggaa gttgcaaaca aaataggata
     2701 tcctgttatg ataaaagcat ctaatggcgg tggcggtaga ggtatgagaa ttgtacatcg
     2761 cgaagaagac ttagagcttg aatatgaaac tgcttgtagt gaatcaagaa aagcttttgg
     2821 agaagatatt atatttatag aaaaatatat agctgatcca aaacatatag aagttcaaat
     2881 attaggtgat aattatggaa atatagttca cttatatgaa agagattgtt cagttcaaag
     2941 aagacatcaa aaaataatag aatatgcacc agctttttcg ttagatgata aagtaagaaa
     3001 agagatatgt gaagatgcag ttaagttatc aaaacatgtg ggttattcta atgcgggaac
     3061 attagaattt ttagtagatg caaatggtgg gcattatttt atagagatga acacaagagt
     3121 acaggttgaa catactgtaa cagagatggt tacaggaata gatatagttc aaagtcaaat
     3181 actaatagcc caaggttaca gcttagatag tgaagaaatt aatataaaat cacaagatga
     3241 tgtggaaata agaggttact ctatccaatg tagaataact acagaagacc ctaagaataa
     3301 attcatgcct gatacaggta aaattcaagt ttatagaact ggttcaggat ttggtataag
     3361 actagatgga ggaaatggat ttacaggggc aaacataagt cctcattatg atagtttatt
     3421 ggttaagaca atatcttggg atagaacatt ccaaggagca ataaataaaa ctataagatc
     3481 tataaaagaa cttagagtta gaggtgttaa aactaatgta ggattcctag ttaatgtttt
     3541 aaataatcct atattctcaa atggtaaatg tagtactaag tttatagatg aaaatccaga
     3601 tttatttgaa ataacagaaa gtaaagacag aggaacaaaa ttacttcaat ttataggaga
     3661 tgtaattgta aatgataatg cttgtaaaga aaaaccatta tttgatgcat tacatgaccc
     3721 aagaatggat aaggatggtt caaaatcaga aggaagtaaa atacttttcg ataagttagg
     3781 taaatctgca tatatagaaa agataaaaaa tgataagaaa ttactattaa cagatacaac
     3841 aatgagagat gcacatcaat cattattagc aacaagaata agaacatatg acttattaaa
     3901 agctgctaag ccaacagaaa aatatcaaaa ggatttattc tcacttgaaa tgtggggagg
     3961 agctacttat gatgttgcat atagattttt aaaagaatct ccttggcgta gattacaaaa
     4021 gctaagagaa gaaataccaa gcataatgtt ccaaatgttg cttagagcat caaatggagt
     4081 tggatataaa aactatccag ataatgtaat agaagaattt acaaaagaat ctgctagaca
     4141 aggtatagat gtatttagaa tatttgattc attaaactgg gttgaaaata tgaaaccatc
     4201 tattaataca gctttagaaa ctggaaaaat tgttgaagca actatgtgtt atacaggtga
     4261 tatactagat aagactaaaa ctaaatacaa tctagaatat tatattaaaa tggcacaaga
     4321 attagaaagc ttgggagcag atataatagc aataaaagat atgtcaggtc ttcttaaacc
     4381 atattcagct tacacactag ttaaagagtt aaagaaaaat gtaaaagcac caatacattt
     4441 acacactcat gatacaagtg gaaatggtgt agcaacttgt ttaatggcgt cagaagctgg
     4501 agtagacata attgatgctg cattagaatc tatggcagga cttacaagtc agccatcact
     4561 taatgctata gtagaggcac ttaagaatac agagagagat acaggaatag atttatttgg
     4621 atatgatgag ttaggaaaat attataagga tttaagaaaa gtttataata aatttgaaag
     4681 tgatttaact aattcttgtg cagaaatata taattttgaa ataccaggag gccaatatac
     4741 aaacttaaaa cctcaagctg atagtttagg attagttaat agatttgatg aagttaaaga
     4801 aaaatataaa gaagctaatg aagttgtagg agatataata aaagtaactc catcttcaaa
     4861 agttgtagga gacttagcta tctttatgac taaaaataaa ttagataaag ataatataat
     4921 agaagaaggt aaaaatttat cattcccaga ttctgttgtg gattactgta aaggtatgat
     4981 tggtcaacca gaaggtggaa taccaaaaga tttacaagag gtagttctaa aaggtgaaga
     5041 agctataaca gtaagaccag gttcattatt accagcagaa gattttgatg aaatagctaa
     5101 atatctaaat gaaaagtatg atataaatgc taatataaga aatgttataa gttatgcttt
     5161 atatccaaaa gtatatgaag attatatcaa acatctacaa cattataatg atatatctaa
     5221 acttgaaagt gatgtattct tctatggatt aaataaaaat gaagaatgtg aagtagaaat
     5281 agaagaaggt aaggtattaa caataagatt agttgaaatt ggtgaagtta aggaaaatgg
     5341 atttagaact ataggatttg agttaaatgg aatggttaga gaagtagaaa taaaagataa
     5401 gaatttctct ggaaaaatta ataatgttga aaaagctgat atgaatgacc ctcttcaaat
     5461 tggagcaagc ataccaggaa aagttataaa aataatggtt aaagaagaag atgaagtaaa
     5521 agcaaatcaa ccattaatcg ttatagaggc tatgaagatg gaaactataa tagttgctaa
     5581 gactgatgga gtaattaagt caatcaaagt aaaagaagat gatatggttg aagataaaca
     5641 attattaatg ataatgaagt aatttaatta aaataaatta aaaagcactc tgaaatgttt
     5701 aataaaaaat gttttagagt gtttttattt attttaatta aatatttgtt aaaaaaaaga
     5761 ggacaattac ctccagatgt agaaataaag ctagtaagga aaatgttatc taaaaattct
     5821 aaatatagta aatattttcc ataatatttc ttaggaaata acagcaaaga taaaatacat
     5881 aaatttaaaa ggtgggtgct tatatgaagg tttatgatag taaaatgttg agaaatgtag
     5941 cggtattagg acatagcgga tgtggaaaaa caaatctaat cgaaactata gcttacacag
     6001 caaacactaa taagatacct aaattaacag acaaggtaaa tatgacttat agcatgggat
     6061 taatacctat agagtataat gattataagt ttaacttatt ggatacccca ggatattttg
     6121 actttagcgg agacgttgtg tcatctctta gagcaagtga tgcagcaata atagtaatag
     6181 atgcaacagc gcctattcaa gttggtacag agaaatcatt agaactaact gagagtattc
     6241 ctaagataat gtttataaat aaaatagata atgaaaaggc aagatacaaa gatgcaatag
     6301 caatgttaag agaaaaatac aataataaga tagttcctat gataagtcct atatacaaag
     6361 ataaaaactt tgtaaagtta cataatgttt ttgaaaacat agatgattta gaaggtgaat
     6421 ttaaggaaca agctatgagt gttaaagaag cattaatgga acttatagca gaaactgatg
     6481 accaaatatt agataaatat tttaatggag aagaactaac tacagaagag atacaaaaag
     6541 gtattattat aggtatacaa agaggtgata ttatacctgt aatatgtggt tcaactataa
     6601 ataatatagg cacaaaggaa atattagata caatatcaag ttatttagaa cctatcttta
     6661 cagaggaaag caaaccattt aggggattag tatttaaaac tatggttgac ccatttgttg
     6721 gaaagatgtc atatataaaa attactgagg gtgtactttc taaggataaa gatgttttta
     6781 atataaataa aaatgtaaaa gaaaaaatag ctaatatata tacattgaga aatagtgaat
     6841 tagtagaaat agaaaaagct aaagctggtg atatagtagt tataactaaa gttaattctc
     6901 taaaaacagg agacactata tctgcagata aagatgcaga agctttagaa aagatagatt
     6961 ttcctaaacc acaaatatat tatgcagtaa ctcctaagaa taaaggtgat gaagaaaaag
     7021 tagcatctgt attaaataaa ctagtagaag aggaccctac attacattgg tatagaaata
     7081 cagagacaaa acaagcactt ttaggaggtc aaggagaact tcatataaaa acaattaaaa
     7141 ataaaatgaa agataagttt ggtgttgatg ttgaattgaa tgaccttaaa gttccttata
     7201 gagaaactat aaaaggaaca gctgatgtac aaggaaaaca taaaaagcaa tcaggtggtc
     7261 atggtcaata tggagacgta aaaataagat ttgaaagatg tgaatctgat tttgaattta
     7321 cagaagaaat atttggtggt tctgtaccaa aacaatatat accagcagtt gaaaaaggtt
     7381 taaaagactc tatgcaaaaa ggtatattag caggatatcc tgttacaaac ataaaagcta
     7441 cgctttatga tggttcatac catgatgtag actcttctga aatggccttt aagatggcag
     7501 caagtgcagc ctttaaaaaa ggtatggaag aagcacaccc aatactacta gaacctataa
     7561 tgaaacttaa gataactgtt ccagaagaat atatgggaga tgtcatgggt gatataaata
     7621 agagaagagg aaaaatattt ggaatggaac cagatgacaa agggaaacaa ataatatttg
     7681 cagaagctcc acaagcagag acatttaaat atgcaataga tttaagagca atgacacaag
     7741 gtagaggata ctttgaaatg gaattagaga gatatggaga ggttccatca cagtttgcag
     7801 aaaaaataat tgggttagct actgcaaagt aatgaacaaa ataaatagaa aaataattaa
     7861 tatatattat taaaaatatt tttagggttt taactaggta taggtttatg ttaggtaaac
     7921 ttatacctag tttttataca tttttgatga ataaaaaaat atataatact ttcttaaata
     7981 ttttaataaa aagaaagtat ttttttatta ttatttttac aaatgtttag taataaagat
     8041 gagaaggtat atttaaaata taaagtattt aaagttctga aatctaatca tgaagcaaaa
     8101 aattagcatt tggttatcaa taaatataat aaataaaaac tcataattaa tgaaagaata
     8161 aattcatgtc taaatttcta taaaaaattt aaatttatac aatttagggc tttaaaaatt
     8221 taaataatag gtgtaaaata atagtcaaag aaagtcaaaa ataaaaaggt gtgtggtgat
     8281 attaatggca actatgacag atataattga aaaatttatt aaagatttga tggaagaaga
     8341 taatagcata caaattcaaa gaaatgaact agcaaacttg tttagttgtg caccatcaca
     8401 aataaattat gtcttaacaa caagatttac aatagataga ggatattaca ttgaaagtaa
     8461 aaaaggtggc ggaggatatg ttcaaataga aaaaatacga aaaagtaaag atgggcatat
     8521 tagagaacta ctaaatgaaa aaataggaag tcagatatcc tataaaaaag caaaagaatt
     8581 attagaaggt ttaaaagagt cggatttgat taacgaaaga gaattaaaat taatattata
     8641 tgcaatagat gataaatcat tgtgtatgcc aatatatgaa ttaaaagaga aggtaaggtc
     8701 taatatttta aagaatataa taataggatt atttagtata gaggagtgat aatttatgct
     8761 atgtcaaaaa tgcaataaga ataaagcatc tgtatattat aataagatag tcaatggaga
     8821 aaaaacagag atgtatttat gtagtgagtg tgcaaaagag aatacagaaa tgaattttaa
     8881 cttagatatg cctttttcaa tgatggatat attttctaat ttaggttttc aacctaaaaa
     8941 agaacttgag gaaaagctag tttgtcctaa atgcaataca acatatagtg agtttaagaa
     9001 taatgggaga tttggatgta gtgaatgtta taatgcattt agtagtcaag taaatccaat
     9061 gcttcaaaat atacatgggc atatagaaca tacaggaaaa gcacctaaaa aatcttttta
     9121 taagataagt gtagaaaatg agattaaaga actaaaagaa gatttagata gagctataaa
     9181 aaatgaagag tatgaattag cagctcaatt tagagataaa attaaatatt taaaaggttc
     9241 tattgactaa gattggagtg atattatgaa agagaacata gtcatgaaat caagagttag
     9301 gctagctaga aatttaaata actatccatt tccaaataaa ttagataaag aatgtgccat
     9361 ggaaataata gaaaaagtaa aaaatgcgtt tattaattct aacttagaac aaaaagaaga
     9421 atttgatttc tataaaattg aagatttaga ccaatctaaa aaaatgctta tggttgaaga
     9481 acatataata agcccagatt tagcagaaaa tgataaaagt gcagttatag taaaaaaaga
     9541 taaaactata agtataatga taaatgaaga agaccatata aggatacaaa ctatatgtga
     9601 tgatttaaac ttagaatatg catatagtgt agcaaatgaa atagatgatt tgttagaatc
     9661 aagtttagaa tatgccttta acacaaagct aggttatcta acatcttgtc caactaatac
     9721 aggaacagga atgagagctt ctgtaatgat gcatttacca gcattaagtc aactaggcta
     9781 tatggatgaa ctttataaaa tttcatcaca aataggtata gcaattagag ggatatatgg
     9841 agaacgaaca gaagcattgg gaaatatata tcaaatatct aatcaactta cacttggaag
     9901 aacagagtct aatattatag aaaatgtaag tggacttaca aaagatgcaa tttcaaaaga
     9961 aataaaagct agagaaatat tgcaaaaaaa attaggtata aaactagaag ataaaatatt
    10021 tagatcgata gggacacttg aaaattcaag agtaatgagt agcgcagagg caatgagcca
    10081 tctatcaaat ataaaaatgg gaatagaaat gaactatata gataaactag atttaagggc
    10141 tatagaacaa cttatgatag gtatacaacc agcgcatcag tcaataatgt ataagagtga
    10201 tgatgttgag aatagagata taaatagagc aacatatatt agagaaactt tggaaaaatt
    10261 aagaggaggg atgaattgtg aacttcaata gatttacaca aagagctaaa aaggcaattg
    10321 atttagcgtt tgaatctgct aaaagtctag gacacaatat tgtcggaagt gaacatatac
    10381 ttttaggtct tttaagagaa gaagaaggta tagctgctaa agttctaagt aaagttggat
    10441 ttacagaagc ttatttagaa ggcaaaatag ttgatatgga aggtaaggga gaagaaatct
    10501 cagaagatat agtattaagt ccaagaagta aacaaatact tgaattatca ggaatgtttg
    10561 caaataaatt aaaaacaaat tatattggga ctgagcatat attattagca attattcaag
    10621 aaggtgaagg aatagctaat aagattttaa attatgctgg agtaaatgat aggactttag
    10681 cccaattaac aattgatatg atgggtatta gtgataaaaa tcaatacaaa gcagaaaata
    10741 gttacacggg caaccagaat caagcagaat ctaaagtact tgataagtat ggaagaaatc
    10801 ttacactata tgcaaaacag aataaaatag accctgtaat aggtagagaa aaagaaatac
    10861 aaagagtaat acaaatatta agtagaagaa ctaaaaacaa tccagtgttg ataggagacc
    10921 caggtgtagg gaaaacagcc atagctgaag gtctggctac aaatatagcc ttaggaaatg
    10981 ttccagaaac actaaaaaac aaaactttat actctttaga gatgggttca ttattggctg
    11041 gggctaagta tagaggagaa tttgaagaaa gaattaaaga agttgtagat gaagttgtta
    11101 aaaatggaaa cataatctta tttatagatg agatgcacac aataataggg gctgggtcta
    11161 ctggagaagg ctctatagat gcttcaaata tattaaagcc agccttagca agaggagaaa
    11221 tacaagttat aggtgcaact acaattgatg aatatagaaa gcatgttgaa aaagattctg
    11281 ctctagaaag aagattccaa ccagttatgg tagatgaacc aactaaagag gactcaataa
    11341 aaatattaga aggattaaga gataaatatg aagctcatca taaagttaaa ataactgatg
    11401 atgctataaa ggcagctgta gaattatcaa ctagatatat atcagacaga tatctgccag
    11461 ataaagctat agacttgatt gatgaagctg catcaaaagt aagattaaaa gaaaatacac
    11521 ctccttcaga aataaaaaaa ttagaactag aaatagaaaa tatagataaa gaaaaagaag
    11581 aagcagtaag atgtcaagac tttgagaaag cagccaaaat aagagatgaa caaggtctac
    11641 ttaaaaaaca attagaagat gttagagaaa gatggaacaa gtcatctaaa cattcagatt
    11701 tagttgatgg agaagttatt gctgaagtag tgggcttatg gacaggaata ccagttaata
    11761 aaattcttga agaagaggct gatagacttt tgagacttga ggaaatactg cacaatagag
    11821 ttataggtca agaacaagca gtaaaatcta tttcaaaggc aatcagaagg tcaagagcag
    11881 gtcttaaaga ccctaataga ccaattggtt catttttatt tttaggtcca acaggagtag
    11941 gtaaaacaga attatctaag gcattagcag aagtgcaatt tggagatgaa aatcaaataa
    12001 ttagaataga tatgtctgaa tatatggaaa aacatgctgt gtcaagaatg ataggttcac
    12061 ctccaggtta tgtaggtcat gatgaaggtg gtcaattaac tgaaaaagta agaagaaatc
    12121 catattcagt tatattattt gatgagatag aaaaagctca tccagatgta tttaatattc
    12181 tgttacaaat tctagatgat ggtagactaa ctgattcaaa aggaagaact gtagatttta
    12241 agaatactat tgtaataatg acatcaaatg ttggagcatc tacaattggt agacaaaaaa
    12301 ctttaggatt tagtatagct aaaggagacg aagaagaaaa atctcaatat gaaaaaatga
    12361 aagaaaatat aatgggtgaa ttaaaacaaa gattcagacc agagttttta aacagaatag
    12421 atgatataat tgttttccac tcactaaatg aaaatcatat atcaaaaata gtacttttaa
    12481 tggcagcgaa actacaagag agattaaaag aaatggatat aaaattagaa atgagtgatg
    12541 aggctgttaa attaatttct aaatctggat ttgacttaga atatggagca agacctctta
    12601 aaagagcttt acaaaaagag ttggaagatg agctatctga agcaatctta aaaggtaatg
    12661 tgaaaaaggg aagtaatgta gtagcaaaag tcaaagatga aaaaatagtt tttgaaacta
    12721 aataatttaa tagagttgca ttttaaaata ttgcaaatat aagttttata atctaaacaa
    12781 aattttaagg gcaatgaatc tataataatt cattgtcctt aattatttta tttaatcttt
    12841 acatattgtc tttcagatat gctaaaatta tagtatagaa taaaaaatta aggatgataa
    12901 aagtatggca aaaataaaaa caaaatatgt atgtcaatct tgcggatatg aaacagctaa
    12961 atggcttggt aaatgtccag aatgtacaaa atggaataca tttgtagaag aaatagacca
    13021 aaaaagcacc aaaaaagagg tctttataat agataaatct tcatctaaac cagtcagtat
    13081 aaactcaata gaaagtaaag aagaagagcg gtttacaaca gatataaatg agttagatag
    13141 agtgcttgga ggaggtatag ttaaaggctc tttagtgctt gttggtggtg accctggtat
    13201 aggtaaatca acacttttaa tccaagtatc tagtaatgtt gccaatttag gaaaaactgt
    13261 tttatatata actggagaag aatcagaatc tcaaataaaa atgagagcta aaagattagg
    13321 tattaactca gaaaatttat atatatttgc tgaaaataat ttaagtataa ttgaatctta
    13381 tttagaaagt gtaaatccag aattaataat tctagactca attcaaactg tcttcagtcc
    13441 agaaatatcc tcggcaccag gaactgtcag ccaaattaaa gaaggtactt caaaattcat
    13501 gaaaatttct aaaaaaatgg gaatttcaac gttcatagtt gggcatgtta caaaagaagg
    13561 ttcactagca ggaccaaaat tattagagca tatggttgat actgttctat attttgaagg
    13621 agaaagatat aatacttata gattagtaag agctgttaaa aatcgatttg gttcaactaa
    13681 tgaacttgga gtatttgaaa tgagggattt aggattagta gaacttgata atccatctaa
    13741 aattttaatc tctgaaaaac caaaagatgt agcaggttca gtaataatat ctactgtaga
    13801 aggtacgaga ccaatgttac ttgaattgca agcattagtt tctcctacaa gttttggtat
    13861 accaaaaaga acatctacag gagtcgatta caatagagta ggtatgttat tagcagtatt
    13921 agaaaaacgt gttggtttgc aaatacaaaa tcaagatgtc tatataaaca tagttggagg
    13981 aataaagata aatgaaccct caattgattt agggatagcc atttctgtag catctagttt
    14041 tagaaatata ccgatagatg aagatatagc tgttacagga gaagtgggac ttacaggaga
    14101 agttagagca gtaagcttta tagaaaagag aatagctgag tgtaaaaaac ttggatttaa
    14161 aaagatagta gttcctagaa gtaattatga tgttgtaaaa gagaccaaag gcatagaaat
    14221 atggccagta gataacttaa gacaagctat aaatatagta cttgggagga atcaataaat
    14281 atggagaatt ttctagataa taaaaatatg ctatatgcat taaaaatgat atctcctgga
    14341 actccactta gattaggtct aaacaatgta ctaagagcta agactggtgg attaattgta
    14401 attgcaacaa acgaagatgt aatgaaaata gtagatggag gatttgctat aaatgcagaa
    14461 tattcaccat catatctata tgaattagct aaaatggatg gagctatagt tttaagtggt
    14521 gatgtaaaga aaatattatt tgctaatgca caacttatac ctgactattt tatagaaaca
    14581 tcagagacag gaacaagaca tagaacagca gaaagagtag caaaacaaac tggtgctata
    14641 gtcataggaa tttcacaaag aagaaatgtt ataacagttt atagaggaaa tgagaagtat
    14701 gtagtcgaag atatatctaa gatatttact aaggcaaatc aggctataca aactctggaa
    14761 aaatataaga cagtattgga ccaagctgta acaaatttaa atgccttaga gtttaatgat
    14821 ttggtaacta tttatgatgt tgcattagtc atgcaaaaga tggaaatggt aatgagagtt
    14881 acaagtataa ttgaaaaata tgtgatagaa ttgggtgatg aaggaacttt agtaagtatg
    14941 caattagaag aattaatggg tacaaccaga atagaccaga aattaatatt caaagattat
    15001 aataaagaaa acacagaaat aaaagaactt atgaaaaagg tcaaaaattt aaattcagaa
    15061 gaactaatag aattggtcaa tatggcaaaa ctattagggt atagtggttt ttcagaaagt
    15121 atggatatgc ctataaaaac aagaggttat aggattctta gcaaaataca tagactacca
    15181 acagcaataa tagaaaactt agtaaattat tttgaaaact ttcaacaaat tttagatgca
    15241 tctattgaag aattagatga ggttgaagga ataggtgaaa taagagcaac atatataaaa
    15301 aatggactca taaaaatgaa acaattagtc ttattagata gacacatatg atgaatttta
    15361 aatgaatttt actacttttt tcttgaatat aatatacact ttggtctata atagataagt
    15421 ataactaggg ggtgaagcat tgataaggaa agtaacaaga atattgttta ttttacttgg
    15481 atttacaata ggtataacaa cctatttaac attaatgaaa gattttgaaa tattaacatt
    15541 tggaaaagaa acatatggtt atatcgcagc tgtagtagca ggtataataa tagccatttt
    15601 aggatatctt atagaaccat gggttgtaaa taaagtaaaa gaaattgcta aaatagtgga
    15661 taaagaattg tcaaaatatc ctcagactga tatattgtta gggtctatgg gtcttatagt
    15721 aggatttgtt attgcgtatt tattaagtgg attagtaaat agaataccaa tagtaggtgg
    15781 aatactatcc ttactattat atttattcct aggatatctt ggaatgaaag ttgcgcttaa
    15841 aagtaaaaat gatttattta atattggaaa actaggaaga ttagcaaatc ctattaagga
    15901 taaagataag gataaagaaa ataaaaaaga agtaaaagcc attcctccaa aagtattaga
    15961 tacaagtgta ataattgatg gaagaatagc tgatatttgt aagactgggt ttatagaagg
    16021 aaaacttatt attcctgctt ttgttttgga ggaactaaga catattgcag attcttcaga
    16081 tgatttaaaa agagtaagag gtagaagagg tctggatata ttaaatataa ttcagaaaga
    16141 attaaatata gaagttgaaa taagtgagag agactttgat gatatagcag aagttgatag
    16201 taaattatta aagcttgctc aggttttaaa tggaaaagtt gttacaaatg attataactt
    16261 aaataaagtt gctcaattcc aaggtgttga agtattaaat ataaatgagt tagctaatgc
    16321 tataaaacca gttgctatac caggtgaaga tatggttgtt caagtggtta aagaaggaaa
    16381 agaggctcaa caaggtgttg catatctaga tgatggaact atgatagttg ttgatggagg
    16441 aagaaaatat atgaatgaga ctataaaagt actcgttact tctgttcttc aaactcctgc
    16501 aggtagaatg atatttgcaa aacctaaaaa ttaatatgtt caaagaaacc tataatttgg
    16561 gctgtttatt ttaaatagat ggtccaaatt tatttattta taacgataat gtttaatgta
    16621 ttcttaaaga tggggattta aatcagaaag cagggagaat ttatgagaaa aaagattata
    16681 tctttcttag caacatttat cataatatta acatcagcaa gtcagtatag ttttgcagat
    16741 gatatatcaa cacgtggaaa agtaatattt atagatatga atagaactag tatgagtaat
    16801 atgttaagaa taaaatcatt aagagaagaa ctagacaata gagggtatat tggcttgatg
    16861 aatataagag gcgataaagg aagtgatgat agaaggtcat atgctagtat gggtgctggt
    16921 ggtagagcta atgtggctaa tgaagaagat attaattttg aaagctcgag taaggataga
    16981 aatatagttt ttgaatcagc tacaggaaaa agtgcaaaag gtataaataa tttaactata
    17041 aataagtcta taaatgaaaa tttaaacttt ggagagtatg gttctgtatt agggtcatta
    17101 ggacaaagtt tatctgataa tggattaaaa gcatctgtat tgggtaattc agatataatt
    17161 gaaaatggtc aacttataaa aaatagaaac ttatgtctaa ctgcaatgga tgaatatgga
    17221 agaataccta atggaaatgt agatactata aataaaaaag acttatctat gccttatgga
    17281 atatcaactg attatgataa attgattgta gagactaaag aaacttacaa aaataatgat
    17341 gtgatttttg tggagcttgg agacacatat agattagatt tatataaacc aaatttaaat
    17401 gaaaaaacat atgagagtat gaaagataac atagaaaaaa atatagatat atatttaaaa
    17461 aatatatttt ctatggttga agaaaatgac actatctaca tagcaagtgc atttccaagt
    17521 gatttagatt ataaaaataa aagaagactt tctccaataa taaaattaaa tggagaaggg
    17581 aaaggtatat tatcatcttc aactactaga agagaaggta ttgtaacaaa tttagatgtt
    17641 ggggttgaaa tattagacaa ctttaatata aaaaatcaaa atatggttgg aagaaaatat
    17701 gaacttatta acagagatga taataaagaa tttttgatgg atgaatatca aaagatagta
    17761 tctatttcaa gcataaggtc tacaatactg aatggttttg taagtatagt tttcttgtca
    17821 tggatagttg ctatgattgc aattttattt agaaagcata tatcaaaaaa ttataaagaa
    17881 acaacatttt ttatattaaa ggaactttta aaaataggaa tagtaatgcc actgtcattt
    17941 atgataacac caataatgaa tttcaaaaca ccattagcaa tatctttagg aataattata
    18001 ataacactta ctatatatct tataagtaaa gttttaataa agaacgattt aaaaaacatg
    18061 ctgtttttta ctggattaac catagtaatt atggttattg atgctgggtt tggctcatat
    18121 ttaatgaaaa gcaatgttat gagttatgat tgtataattg gagctagata ttatggagta
    18181 ggaaatgagt atcaaggtgt ggcaatcggt agtgcaatat ttacatttgc aattttactt
    18241 acatataaaa atataccaaa gtggtatata atagtttttt ctttggttat cttaattaca
    18301 agtgcatctc caattatggg agcaaatgtt ggaagtgcta tttctgaatg tgttgcattt
    18361 ttactattta tactattgat atataatgta aagatagatt tcaaaaaaat cgtattatta
    18421 ggtatagcag tagtatttgt attaggagtt tttgtagcaa tagatatgat tttgggaagt
    18481 aattcacatt taggtatgtt tgtaaaagaa atttacttta atggaccagg agaaataata
    18541 caaacattta gtagaaagat agagatgaat ttaaagctag ctcaaaccag tgcatgggta
    18601 aatatactgt taactggaat aggtgtaatt ttagttctta tgattaatca gattagatac
    18661 tttaagcaac tgatggatga gtatccaatt gtatttaaag gatttatagc atcaatagca
    18721 ggatgtttag taactctttt agtgaatgac tctgggattg tgtcatcagc tacagccttt
    18781 atttatgtaa ttgtacctat gataacatta agtataaatc ttacagcatt aaaagaataa
    18841 gtactgtatg aataatatgt aaatattaat acattaattt aacttcttta tttacaaaat
    18901 aaagaagaaa gtttataaaa aataaattat aataaaaaag agtttatctc aaaattgatt
    18961 attctaatca aattttaaga taaacttttt ttattataaa gataaataac atataacctc
    19021 atattttagg tagatttttt tcttatatgt ttaggagtgc atttaaattt ttccttaaaa
    19081 attctgtaaa ataattttgt attagtaaat ccatgagctt ctaatatact gcataaggta
    19141 tcatttgtgt taattaaatc tttataaata tgagaaatac gcacatcatt taaatactct
    19201 aagtaagttt gtcccatata ctgtttaaat tttctacaaa aatattctgg ttgtaagtgt
    19261 gctaccttag cgattttgtt aatagaaata ggcattttgt aattaatctt tgtatattct
    19321 aaaactggtt caaattttga caaatcaagt actgtttttt tcatattttt attacctaca
    19381 gatattttaa agtttgtata taattcaaat aaaagttcaa ataataagct tgtaaagagc
    19441 agattagctg caggaggaga actaagttta atttctctca tgttttctaa tataagttta
    19501 actttacttg aatttttttt atagttattg tcattggcat taaccttaaa gtcaaaatag
    19561 caatttttaa aatcagggat atatttgttt agaaaagaca atggtacttg caataatata
    19621 gaggtatttt gataaataca tctagttgag tgaataattc cagaattaat gaacatacac
    19681 tcattagctt ttaaattata agtgtaaccc tccatgttaa tttgtaaatc accagaagtt
    19741 atataaatta tttctaatga gttatgccaa tgatttgcta cataactacc actatcatca
    19801 aatagtttga aattaacatc taaattatca ataggttcaa ttatttcatg tgaaaaatta
    19861 tttctgttca taataatatc ctccttataa ttttaaatta taaatagtaa atttataatg
    19921 ttcaatatta aaaagataat atagactaat aaattagata ataaacatac ttaagaaaac
    19981 ggataaaatc aaatataata actgtatatt aaaataactt aaaaaaatta ttttattata
    20041 agtgcaaaat atacctattt aaataagata agaggggagg attttatgtg tatataaaag
    20101 gtgtaaattt aggaggttgg ttagttttag aaaaatggat gacctcaagt ttatttgaag
    20161 gcacagaagc tgaagatgaa tactatttac caagacagct ttcaagagag gcatatgaat
    20221 ctagaattaa gactcatcgt agtgaataca tcacagagag agattttgca acgattaaat
    20281 ctatgggatt taattcagtt cgtataccag taccatactt tatttttgga gattgtgaac
    20341 cattcatagg atgtgttaaa gaacttgata aagcatttgc ttgggcagat aagtatgggc
    20401 ttagtatatt gatagactta catacagttc caggaagcca aaatggattt gataatggag
    20461 gaatatcagg tatatgtagc tggtcacaaa atccagaata tgtagcgttt acattaaatg
    20521 tattagaaag acttgcaaaa cgttatggga tgaggcatga attgtatgga atccaaattt
    20581 taaatgagcc tataacagaa agaatgtgga acataatgaa tgttccaaat cggtttaagg
    20641 ctgtagataa ggagatggca agggggagta aacctaattc attagagttt ttacgtgatt
    20701 tttatataaa agcatatagg gtaatgcgtc cttatatgag agaggaaaac gttatagtgt
    20761 ttcatgatgc atttgaatta aaagcatgga aagactttat gagagaggaa gaatttaaaa
    20821 atgttgttct agatacacac caatatttga tgttagctga agcagatgga tgtgaacaaa
    20881 gtattgatag ctatctcaaa tatattagag aaaattatgc taaagatatt ttacaaatgc
    20941 aaaaatattt tcctgttata tgtggggagt ggagcttatt taattcatat gtttgtggta
    21001 tagatacaaa tggaggtcaa tcacctctaa atgggattga atcaaatata gataaattat
    21061 caaaagacga taaaagagaa ttatatagga agatagcaaa agcacagctt gatgcatgga
    21121 gaaatggaag tggtcactac tattggaatt ataagttatt actagataca gttaatgaag
    21181 aaggttggat aggatgggat agttgggacc taggcaaatg tgtagctcaa gaatggtatc
    21241 ctatagaata ttaaactaaa attggaggaa aagatatgat taaaaaccct atacttccag
    21301 gttttaatcc agatccttgt atttgtagaa agggagatga ttattatctt gtagtttcat
    21361 cttttgaatg gtttccaggt atacctgttt atcactctaa agacttaaaa aattgggagt
    21421 tatatactca tattttgaca gatgaaacaa aaatagattt gaagaagctt ccttcatcta
    21481 aaggaatttg ggcaccctgt ttgacttatt gtgaagaaga agatttattt tacatagttt
    21541 atggaattat gaactctatg aatgcaagat attttgatgt tgataattat ttaattacat
    21601 caaaagatat aaagggagag tggagtgaac cagtatatct acactcatca ggttttgatg
    21661 cgtctatttt tcatgatgat gatggtaaaa agtggattgc atcattagac tgggagacta
    21721 gagaaggata tgaaaaacct ggtgttatat gtttagtgga atactgtaca aaaaagaaag
    21781 aaatagtagg atatccaaag agaatatggt cagggggaac tgatagaggt tgtattgaag
    21841 caccacatat aacaaagcgt ggagattact attatataat gtgtgcagaa ggtggaactg
    21901 gatatggtca tagtgtaact atgggaaggg ctaaaaatat atggggacct tatgaaaaag
    21961 attcaatgaa tccaattgta acttcaattc caggcgattt ttatgaaaga catgaccctg
    22021 accatctaaa gcctaaatac tataatccag aatcaaaact tcaaaaatct ggtcatggaa
    22081 gctatataga aacaacatca ggtgaagtat atttagttca tctaacatct agaccatttg
    22141 taccagagtt aaggtgtact ttaggtagag aaacagctat tcaaaaaatg aaatggacaa
    22201 aggataattg gcttcgaatg gaagatgaaa gtaatttggc aaaagaatac gtatcagaaa
    22261 gtaaactaga agaacattta gtttcatcta taccaagttt tgatgacttt gattcaaatg
    22321 aattaggttt acagtactat gctcctagga tttcaccatt atcatttgca gatgttaagt
    22381 ctagaccagg atatgtaagg attagaggac aagaatcaag aacatcatta aataaagtaa
    22441 gcatattggc aagaaaatta acttcagtat atgcaagaat aaccactaag atggagtttt
    22501 acccagaggt acatcagcat agtgcgggtt tgataatgta ttatgataat atgaattata
    22561 taaatttaag aaagtattat agtgaaacat tgggtcaaag tgcactatca ataatacatc
    22621 ttgaaaatgg agagaaaacg gaatttttaa atactaggat accaataaaa gatataccaa
    22681 tatatcttcg tctgtatata caaggtcgta agtcatattt tgaatggagt tatgatgaaa
    22741 aaaactacca gagaatagga aaggtatttg atacaactaa gttttcagat gagtactgta
    22801 aatatggaga atttacaggt acgtttatag gattaacttg tgcagatcgt gtaaagcata
    22861 aacactatgc tgattttgat ttttttgaat atatagtaga tgaatcaaaa gatgtcgatt
    22921 aataaaatca ttactaaaat tttcagagca aaggtaaatc ttatgctctg aaataagaaa
    22981 cattagaagg caaatcttac aaaaaggagt atggtattat gaatacagaa gttaatgtta
    23041 aagcaactac gattagatat gaaaagattt cattttttga aagaatttct tatggttgtg
    23101 gggatttggg gtgcaatatc atatactcag ctatgtcagc atttttgctg ttttattata
    23161 ctaattatgc agatgttagt gcagcagctg taggtagtat tatgcttgta tctaggatac
    23221 tggatgggtt tagtgactta acaatgggaa ttatagtgga tagaactaaa tccaaatacg
    23281 gtaaggctag gccttggatt ttgagaatgg cgattccttt tgctatagca gcagtattat
    23341 tattttctgt tccatcaaat cttggtatca cttctaaatt aatttatatt tttattacat
    23401 ataacttagt ttctactgtt atttatacag caatcaatgt accctatgca actctaaatt
    23461 cacttataac tcaaaaccag tatgaaagag gagtattaag tatatttaga atgatattag
    23521 ccacttgtga taccttacta ataaatggac ttacactacc tctagttgaa tactttggaa
    23581 ataatttatc agcatggact aaaacattct ttgtatttgg aatagcatct ataatggtat
    23641 tttttataac atttactgga accaaggaaa gagtaaaagc agttaagcaa gataggaatg
    23701 aagtaatacc atttaaaata ggtattaaat ctttatttag aaataagtac tggatacaaa
    23761 taacattatg tttagtttgc atatttattg tatttgcgat aaatggtggt tcatccgtat
    23821 attatgcaaa gtttattttg ggagatgaaa aattatttgg tcctataaat atggtttcaa
    23881 atatatccca aattatagct atgtttatgg ttgctccttt tataaaaaaa tttggaaaaa
    23941 gaaatgtatt aatagtaggt tcaataatat taatatcgtc aaatgttatg tttataatag
    24001 ttggacaaaa tcatatagga gtaatatttg caagtgctat aaagggaata ggaagtgctg
    24061 gaatagcatc aacaatgttt gctattgttt cagatactat tgaatatgga gaatggaaga
    24121 ctggatatag aactgagggg cttataaata gtgcatctag ttttgggttt aaagtgggaa
    24181 atggattagg ttcagcaata ttaggtgcag tattatcaat tggtggttat gtaggaacat
    24241 cagctactca aagtgattta gctatagtat caataaaagt atgttttata tacctaccta
    24301 tatttataac aatattacaa attatcataa tgtcttttta taagcttgat aaagaatata
    24361 gtactatact taatgaatta aatactaaat aatgaaaaag tttcttataa agtcttaagt
    24421 ttaattaagg tctattgtaa atgttcccta taaaaactat tatatattta tgattattga
    24481 agaattttta gagaagcgaa taataaaaat ataagaagac tttaaatgat gaaatggttg
    24541 gttttttaga aatgatttaa taagttattg ttatttaaag cattataagt ggacaattaa
    24601 tttttaattt atggagatga tatttaacaa ttagaagtaa tatataatat gcactaagaa
    24661 gcaatttttc aactatttat gaaggtggtg gtacaagaaa agtatcacct tttttttgtt
    24721 atacaaaaaa acagttgact ttttatatga accccttcta taatgttact gaaattaagt
    24781 aaaatgattg aacaaatgta aagataattg aaaagcttga ttttggagga aagcaaatga
    24841 aaaaaattgg agacttaaga ttaatgatga agtgttgttc actttattac gaagataatt
    24901 tgaatcaaca ggaaatagca aatcaattgg gaatatcaag accaacaata tcaagaatat
    24961 taaaagaagc ttttgaacaa ggaatagtaa aaatacagat agttgatgtt ttgaaaaatg
    25021 attaccaaaa aatagagaga agtttggaga gaaaatataa attaaaagaa gtaatagtag
    25081 tagatgataa acaggatgca ctaacacaaa aacaagaact agcaagagct gtatctgaat
    25141 atttaactag agtagtaaag gaaaatgata taataggtgt ttcaatagga acaacactaa
    25201 aagaaatacc aagatatgtg gaaaaaagta actgtaaaaa tgttacattt atacctctat
    25261 taggagggat tggagacaat gaaatagata ttcatgcaaa tcaaatagcc gtaagtttag
    25321 cgagggcttt tggaggtgat tttaaattat tacatgctcc agctgttatg tctgacttgt
    25381 ctacaaaaga gaaactttgc aaagacgaaa aaattaaaga agtactagat ttaatagata
    25441 aaacaactat agcaattgtg ggtataggaa atcctatgag tttaaactca acaataatgg
    25501 cttctggata catgaatgaa gcagatatag aagatttaaa aaaatacaac tcaataggtg
    25561 caatttgttt acaagccttt gataaagaag gaaaaacttc tatacttgaa tttaatcaaa
    25621 gagtattagg agtgaaactg gaagatttaa aaaagataaa aagaacaata ggtgtcgctt
    25681 caggagatga aaaaatagag gcaataaagg catcattaaa agcgaaattt ataaatagtt
    25741 tagcaattaa tcacagttta gcacttaaat tattagaaga ttgtgactaa tagaaagata
    25801 gataaaagtt aacaggaggg aatgtatatg tcaatatcaa aagaaacatt gcttgaaatg
    25861 tataagagaa tgaatcaggc tagaaaattt gaagagaaag ttagttggtt ttttgcaaga
    25921 ggtatggttc atggaacaac tcacttatct gtaggtcaag aagcgtcaag tgtggcggct
    25981 gtaatggctt tagaaaaagg agatttagta tcattaactc atagaggaca tagtcaattt
    26041 ataggaatgg gaatagacct aaataaaatg atggctgaac ttatgggtaa agaaactgga
    26101 ttttgtaagg gaaaaggagg ctcaatgcat atagcagata ttgagtcagg taacttagga
    26161 gcaaatggag ttgtaggtgg aggtcttaca atagctccag gagctgcact tacacaacag
    26221 tataaaaaaa caggcaaaat agttttatgt agttttggtg atggagcatc aaatgaaggt
    26281 acttttcatg aaggaataaa tttatcttca atatggaaat tgccaataat attttactgt
    26341 gagaataatt tatacggtat gtcaacaagc ataaaacgtc atatgaatat agaaagtatt
    26401 gccactagag cagcttctta tggaatagaa ggaatatcaa tagatggata taacccaata
    26461 gaagtatacg aaacagtaca aaaagctgct gagaagtgta gaagaggaga aggacctgta
    26521 ttaattgaaa gtagaactta tagatggtta ggtcattcaa aatcagatgc aaatgtatat
    26581 agaacaaaag aagaaataga atcatggaaa gcaaaagacc ctattgaatt tttaaaaaat
    26641 tatcttatag aaaataatct atctaatgaa gatgaattag ataagattca agaatttgca
    26701 aagcaatcaa tagaagatgc agtagagttt gctcaaaata gcccaaatcc aaaaatagag
    26761 tctttattag aggatgtata tgcagactaa gaatggtaaa ggaggaaaat aaaaatgagt
    26821 acaagggaat taacatatgc acaagcaata aaggaagcaa tgtcagaaga aatgagaaga
    26881 gatgaaaatg taatatttat gggagaagat ataggaatat atggaggagc atttggtgta
    26941 tcagttggta tgatagatga atttggacca gaaagagtaa gggatactcc tatatcagaa
    27001 gcagctatag caggagcggc agcaggtgca gcagcaactg gcttaagacc tattatggaa
    27061 gtaatgttta tggactttgt aacaatttct atggatgcaa ttgtaaatca agcggcaaaa
    27121 atgagatata tgtttggagg aaaagcacaa gttccaatgg ttgttagatg cccaggaggt
    27181 tctggaactg gttcagcaga gcaacattca caaagtttag aagcttggtt ttgtcatgta
    27241 ccaggagtaa aagtagttgc accttctaca ccagcagatg ctaagggatt gttgaaagca
    27301 gctataagag ataataatcc agtcatattt gttgagaata aattgttata cagaaaaaaa
    27361 ggttttgtgc cagaagatga ttatgtaatt gaaattggaa aggcagatat taaaagagag
    27421 ggtactgatg ttacagtaat tacttatgga agaatgttac aaagtgttga agaagcagca
    27481 gagactctat caaaagaaaa tataaatgtt gaaattatag atttaagaac tttatatcca
    27541 ttagataaag agactatagt aaagagtgta tgtaaaactg ggagagtttt aatttgccat
    27601 gaagcagcta agactggtgg gctaggtgga gaaatatcag ccctgataac agaaagtgaa
    27661 tcatttgatt atttagatgc tccagtaaaa agaatttgtg gaaaagatgt gccaatacca
    27721 tataatccag agttagaaaa agcagttgtc ccaagagttg atgaaataga agaagcaata
    27781 aaatctttaa ttgttagata aggagggata gatatggtgg caaataaaat aaaagccaca
    27841 ccagcagcta gaagtcaggc aagaaaagac aatataaaat tagataggct gattggaagt
    27901 ggagaaaatg gaaggattca tttagtagat gtgttaaatt atttaaaaga taataaagca
    27961 aatactactc ctttagctag aagaatagca gaagatttaa atatagattt agaaactatt
    28021 gtaggtactg gatataatgg aaagataaga aagtgtgatg tggaaaaatt aactggaaaa
    28081 gaaactattg tatcaactaa tacatctaaa tctagtgaga aaaaagagct gaaaattgaa
    28141 aatgaaaatt caagaatgtt taacacagta gaaggaatat ttgaaaagcc aaatccaatg
    28201 agagctactg tagcaaaacg aatgtcagaa agttatttta gtgctcctgt atttacattc
    28261 aatatagaag tagatgctac agaattgaag gtacttagag caaagttaat cgacacagta
    28321 aaagaatcaa ctggagtaaa attaactatg acagatttaa tagtaatggc agtatctaaa
    28381 atacttccaa atcatcaagc cttaaattca gcatggacag atgagggtat atttagatat
    28441 aaagatgtaa atatagctat tgcagttggt ttagatgaag gcttatatgt tccggtagta
    28501 aaaaatgcaa acaaaaagtc tttaaaagaa atagcaaaag aaagcaaaga acttgcggaa
    28561 aaagtaaaga cagggaaact tatgccagca gaccaagaag gtaatacatt tacaataagt
    28621 aatgttggaa tgtatggtat aactacattt acacctataa taaatatgcc ttcaagtgca
    28681 atcttagggg taggtgctac acaagataag tttgttccag taaatggaga ggctaaaata
    28741 aaacctataa tgaacttatc attaacatca gaccatagag taatagatgg aacagtagct
    28801 gcaaaattct taaaagattt aaaagaattg ttagaaaatc ctttatcaat gcttgtatag
    28861 gttttgatat tttgttactg atataaatag tttgaataga ttatattatt ataattgttt
    28921 cagtaaattt aaagctttta tatattaaga attattttta acagtaacta tatgtgaata
    28981 tgatttgctt aattaaaata tatgaaaata aataggagga gagcctatgt cagtagaagt
    29041 aataatgcca aaagcaggag tagccatgga agaaggtact atagtatctt ggctaaagca
    29101 agaaggcgaa gaagtaaaga ttggagaacc tatactagaa ataacaacag ataaagttaa
    29161 tatggagata gagtcagaag gagaaggtac acttgctgta atcatacata aagaggaagg
    29221 tgaagtatta ccagtattta cagtaatagg tgtaatagca gaaaaagggg aaaatcaaga
    29281 ggaagtaaaa gctaaatatt tatctggaaa tgtttcaaaa gaagatatag ttgaagagaa
    29341 tcaaaatata gaatttaaag aagaaaaaat aaacaaaaaa gagtgtaatc atgattatga
    29401 tgtagtggta ataggaggag gacctggggg atatttatca gcattaaaag cagctctttt
    29461 aggtggaaga gttgctttag ttgaagaaaa tatactagga ggtacttgct taaatagagg
    29521 ttgtatccct acaaagactt atataaaaac agcagaaata ttagaagaaa ttgaccaatt
    29581 atcaaagaga ggtgtaaaag taactgtaga taaagaacag gacattaaga aggccataaa
    29641 atataaaaat agagtagtta aaaaacttac agctggtgtt ggcggattat taaaaagtag
    29701 agatgtagat gtgtttaatc ttaaagctag tgttaaagaa gagcataaag taattttatc
    29761 agatggaaaa gttttagata cagaaaatat aataattgct acaggttcca aagtaaggat
    29821 attacctata aaaggaatag aatcaaattt aataataact agtacagaag cattagattt
    29881 ggaaacagtg ccagaagaat tagtaataat tggtggtgga gtgattggtt gtgaatttgc
    29941 agagatattc aattcaagag gttctaaagt aactatagta gaaatggaag atagagtaat
    30001 cccaagaatg gataaagagt taagcgaatc tttaaaatat tctcttagta aaaaaggtat
    30061 aaatgtatta actaaaaaga aagtttctga atttaaagaa gaaggaaata acatattagt
    30121 gtgcattgaa ggtgaagagc caataaaagc agatttatgt ctatatgcta taggaagaga
    30181 agctaatctt tctggcatag aggacttaga tattaaaata gataaaggtt caatagttgt
    30241 aaatagtaaa atggaaacaa gtataccaag catatatgca gtaggtgatg ttactggagg
    30301 tgtaatgtta gctcatgctg cttttaaaat gggagaggta gcagcttcaa atgctctagg
    30361 tgtgaataaa gaagttgact taggtgcatt acctagttgt gtttatacaa ttccagaagt
    30421 agcatcagtt ggtattacag aagaggatgc tagaaaaaaa tataatgtaa aagttggtaa
    30481 gtttaatttt gctggaaatg gaagagcttt agcttctggt caagaacaag gatatgtgaa
    30541 ggtagtagca gatgctaaat atggagaaat tttaggtata catatgtttg gatgtggtgt
    30601 agcagaactt ataaatcatg cagcatcatt taaagcgtta gagataccta ctgatgaagc
    30661 aagtgagttg atatttggtc atccatgtac ttcagaagct ttaatggaag ctttggcaga
    30721 tgtaaatgga gaatgtttac acttacctaa aaaataaatc taaacataaa ttattaattt
    30781 aagtctatta ttaatattaa tttatatcat aaaattttaa aacacttact tagccatacc
    30841 ccttattatg caaataattt atttgcataa taaggggtat tttttatgga aaaatataga
    30901 atatagaatc cttgtagttt ttgttgtaca aaaaagatag taatataaaa taacattatc
    30961 attttagaat gatttcaatt gtaattagga aaagtgattt ttttgttttt aaaaaaagta
    31021 ttatttgtaa aatataaaaa aaaatttctt aatatttgaa taaaagaata gcttaattta
    31081 aatgttatta ctttataaaa aaataataag tacaaaaaaa acaatatatg gcatataagt
    31141 tgctatataa ataataagga gggaacaatt ataaatgagg caaagaataa aaaacttaat
    31201 tgaaaatgaa gataagaaaa atcctttaac agatgaagcg atttcaagta ggttaaatat
    31261 tcgaagagaa gatgttacct ttttgagaaa tgagttaaaa atagaagatt caagacaaag
    31321 aagaaaagtt gttttaatta aagctataaa agatatttta aaagaagaaa aaactataaa
    31381 taaaaatgat ataacaagaa gattaaacag cattgggttt acagtatcaa gatttacagt
    31441 catacaatac ttaaaagaga ttcaagattc tggtgaccta aaacttgata aagagagtga
    31501 tgataaaaaa gaagaaataa tcaataatag agaaaataaa gatatagcat ttgataaact
    31561 tataggtagt agtggtagct taagtacaat tataaaacta gccaaagcag caattcttta
    31621 tccacctcat ggtcttcata ctattattat ggggccaact ggtgttggaa agagtgagtt
    31681 agcagagtgt atgtataaat ttgcagtaga atcatccaga ttccctaaga atgcaccatt
    31741 tatagttttt aatgcagcag attattcaga gaatccacag cttttgctat cacagttatt
    31801 tggacacgtt aaaggtgctt ttacaggagc tgatgagaac aaagaaggat tagtatcaaa
    31861 ggcagatgga ggaatattgt ttatagatga aatacataga ttacctcatg aaggtcaaga
    31921 aatactattt caactgattg ataaaggtat ggtcagaaag ttaggagaaa caagactaac
    31981 acataaaata gatgtaatga ttatttcagc aacttctgag ccaatagatt ctcatttact
    32041 taatacattt aaaagacgta tacctgtaac aattgaaata ccagaattag ttgcaagacc
    32101 attaaatgag aggtttgaca ttataaataa tttcttctta atagaagctc aaagaatggg
    32161 agcaaacata catataaagt cagatgtatt aaaagctctt atgctttacg attgtatagg
    32221 taatgtaggt caacttagaa gtgatattca agtagcttgt gctaggggac tattaaacca
    32281 acttacaaac aaactaaaag aagtaaatat aagcatatca gatgtacctg gatatgtaaa
    32341 acaaggtctt ataaaaatca gaaattgtag agggaaaata gaaaattatg tagatgggga
    32401 tttaattata gactcaaatc ttcaaggtga gatagaaaag aaaaatgaag atatatatac
    32461 ttttccagat gaaatataca aacttactga aagaagacat attgatttat tggaacaagg
    32521 tttagatttt gatgttataa atagaatcat tggaggagaa ttagaaagtt gcattcaaaa
    32581 atacataaaa caagttaaaa aagtttctat tagtaacaat cttccagata taagtccaat
    32641 tgttggaaaa tatatcgtag agctaactta tgaagtaatc aaaatagcat cacaatacct
    32701 aagttcacta gaaccgaatc tacatttatg tttagcagtt cacctaaaag cagcttttga
    32761 gagattaaaa gaaggaaaag taatatcaaa tgctcatttg aaagaaataa taggaaatta
    32821 tccagtagaa tattctgtag cagaaaaggt agctcaatat ttaaaggaaa gatataacat
    32881 aaacttacca aaagaagaaa taggtataat agcaatatat tttaaaatga gtagtagaag
    32941 agatatgtct gaacaaaaaa agataggcgt acttcttatg gctcacggaa gagtagcatc
    33001 ttctgtatgt gaggttacaa ataaactatt aggaattaat cacgcaaggt atttagatat
    33061 gccatttgag aagaagccgg aagaaatgat tgaagaagct actacaataa taaaagatat
    33121 tgatgaaggt agaggtgtga ttatattagt agatatgggt tcactttcat attttggaga
    33181 tattatttct ggaaagactg gaattaatat aaggacaata tctagatttg atacattgct
    33241 ttctatagag gttatacgaa gagcagtttt accagattta acaatagacg agatagttga
    33301 tgaagttaaa ggtatagagc cacaagtaaa agaaaaggtt agtaaatgta acaatacaaa
    33361 agtagatttt agaaaaccta taattttaac attatgtatt actggattag ggggagcttg
    33421 taagataaaa aaaatcttag aggaaaatat taaaagtata actgaaaagg ttgatataga
    33481 acctataggt atgattgaat atccaagtct tgatttagag ataaaacaaa taagcaatga
    33541 taaaaatgta atcgccatag ttggaacaat tgaccctcag atagcaaata tccctttttt
    33601 tagtctagta gacataaatg ataaagcgaa gttaaatcaa ataaataacc taattgatac
    33661 aaatcaaatt ggtgaaacaa ataaaaaata tgaattatca gatttaatac ataaagaaga
    33721 tatatttgtg gatttacagg ttaaatcaaa agaagaagtt ctaaaatata tgagtaaaaa
    33781 acttagagag aaaggttatg tgacaaaaaa tttctataaa aaagtagtgg aaagagataa
    33841 cttatttcca actgaattat cagatgaaat agcaatacct cacacagatg gaatagatgt
    33901 aattaggcca gctataagta tagccatctt aaagaagcct attgtgtgga gtaaaagtaa
    33961 agtaaaaata atacttttat tagctgtaga ccaaaagtgt tttaatccat taagcactct
    34021 actctcattt atagaaacag atgaatttaa gaagataaaa aacattaaag atagagattt
    34081 tattagggag atgatattag atggagtcaa tgaaaataat tagtagcaat ttaattttta
    34141 aaaatattga agtgtctaac aatgaagatg cattaaagtt tttgggacaa cgtttgtttg
    34201 acgaacagta tgtaaaagaa agttacatac aagctgttgt agcaagagaa aaaaagtatg
    34261 ctacagggtt accaacagaa atatacggag tggcaatacc acatacagat atagtacatg
    34321 taaatgagcc aggaatagca attggaatac tgaataaacc tgtaaaattt ataatgatgg
    34381 gtacagacga tactgaaatt gatgtaaaag ttgtatttat gttagcagtg aaagagccac
    34441 aagaacaatt gcaactatta gaaaaactta tgactatatt tcaagataag aatatactaa
    34501 ataatattgt tgacttaagt gaagaaagtg tgagtgattt attaaactct aaattgaaaa
    34561 attaaacatg taaagtatat taaaaatgta aaattaaaca tgcaaagtat gttaaaaaat
    34621 ataaaaagat tattaaagat ttctaactat agatatcttt aaaataaaat aatttcaatg
    34681 ggggtgacta atgtggctaa aaagatatta gttgcatgtg gaacaggagt atgtacttca
    34741 acaattgcta taaacaaatt aaagaaagca cttcaagaca ttggtaaatt ggatatggtt
    34801 aatattacac aatgtaaagt agtagaagtt gcatcaaaag cacctgatta tgatttaata
    34861 atttgtacta cacaagtatc tagtagtata aaaacaccag tgataaatgg attacctttt
    34921 ttaactggtg tcggaatgga taaattaatc aatgatgtat tagaagagtt agaattataa
    34981 ttaaaaaaat taaggaacat ggtctctaaa atcataagtt ttagagactt aaaattaaat
    35041 aatggagggt ctttatatgg agatattaaa tttcattgtt ggtctaggtg cacaagtaat
    35101 gatgccaata ataatatgta tttttggttt gatattaggt acaaaactag gaaaatcttt
    35161 aagagctggt ttaactgtgg gagttgggtt tataggtctt aacactatta tagctttgct
    35221 aacagataat ttaggtccag ctacacaaca aatggttaag aatttagggc taagtttatc
    35281 aataatagat gtaggatggc cagcagcatc agctatagct tttgcatcaa cagtaggggc
    35341 tttaattatt ccaataggtc ttgtggtaaa tatagttatg ctaattacta atactactca
    35401 aactgttgat gtagacatat gggattactg gcattttgct tttacaggag ctttagtggc
    35461 aggtgctact caaagtgtaa tgtggggagt atttgcatca gtagcaaata tggtaattgt
    35521 attggtaatg gcagatttaa ctgctccagg tatagaggaa tatttaggta tgccaggtat
    35581 atctcttcct catggattta cacaggcatt tgttccaatt gctatagtag taaataaatt
    35641 attagaccta ataccaggta taaataagat tgagataaat gctgatacat tgcagaaaaa
    35701 atttggatta tttggagaac ctttaataat ggggtctgta ataggtgtaa taattggtat
    35761 tgctgcgaaa tatgatataa aaggaatatt acaattaggt gtaactatgg gagctgtatt
    35821 aatattaatt ccaaagatgg cagcattatt aatggaagga ttattaccag tatcagaagc
    35881 tgcacaggaa tttattgaga agagatttaa aaacagaggc aagatttata taggcttaga
    35941 ttcagcagta ggaataggtc atcctgttac attatcagtt gcactagtgt tggttccttt
    36001 gactatactt atagcagcta tattgccagg aaataaagtt ttaccatttg cagatttagc
    36061 agtaattcca tttgcacttg tattaatcgt accaattaca aagggaaatg tgtttagaac
    36121 attaataata ggaataatta taattacttc tggattatta atcgcaacta acttagctcc
    36181 attatttacc caaatggctt taaatgctag ttttaaaatg cctgaaggag caactatgat
    36241 ttcaagtatt tgtgatggtg cgaatccatt aagttgggta tttgtaaaag ttatgaacta
    36301 taaagttatt ggaggagtag tttttggagt tatagcttta ggaatggcta tttacaatag
    36361 gaatagaata ataaatgaaa ataaaaagct atctatagaa gaataaggtt aaaacaattt
    36421 tattaaggag tgtataggtt atgaaaaaat ataaatatga ttctaaaaga tacttactca
    36481 gtgttacaat accaggattt tttatgattt taatattgat ttatgcactg tttaataact
    36541 atacaaattt taatttgaat atatatagtt tgttaataat tgtctgtact tatggtatat
    36601 tcaatacttt tatatcatca agtaatccta aaaaaattat tattgatagc aaatgtatac
    36661 attttacctc atttatgact acacataagt atgaaattaa agatatagaa aagataagaa
    36721 taagagaatt ttataataaa aaaatttatg taaaaattaa tgatggaaac ctttttaaag
    36781 gtaggtattg gataagaaca aatatgttta ataatagtat agcattatat agctatttca
    36841 ttgagttgga agagtgctta tatccagatt cactaaaatt tagaaataaa aaatttgaga
    36901 ataagaacat ataaaaataa aaaattgaat tgaagcctag cttaatcttt tttgataaga
    36961 tataagtttg aactttatac taaattttta gaattttcaa tcaagacaat aacataatag
    37021 ctaagcaatt agaacacaat taagatgtat aaggcatgta tatgatgaat gggaggattt
    37081 aattaatgtt attagagaaa ttaagaaaag aagtattaca agcatcttta gaccttttaa
    37141 actataattt agtgacatta acaggaggaa atgtaagtgg gagagatgaa caaactggct
    37201 atatagcaat caccccaagt ggaatggatt atagaaatct tacaccaagt gatattgtta
    37261 tagtagatgt agatggaaat attatagatg gaaaatggaa agcatcagtg gatttatcag
    37321 accacttgta tatatataag catagagaag acataaatag tataattcat acacattcta
    37381 catactcaag ttgttttgct attttaaatg aacctataga atgtgcaagt acaactcttg
    37441 caaatgaagt agggggttca gtaccagttg caaaattttc accaccaaca tctaaaaaga
    37501 tgggaaaatg tgttattgaa gcaattggtg acaaaagagc atgtctttta gcaaatcatg
    37561 gcgtaattgc agttggtcca tctgtaggac atgctcttac agccgctgta atgttagaag
    37621 attcagcaaa agtatattac ttagcaaaat caattggcac accagtgcta ctgcctgatg
    37681 aagaaattca aagagcgaga gatgtatttt ttaatgtcta tggtcaggat aaataaatta
    37741 gataaaattt taaaagtaat atgaaaatat agatattcaa tgatattaag gagatttata
    37801 atgatataat aagtttaata gttaagaagt aaaatatgaa atgtaatagt atataaattc
    37861 atttaagact aaaaagaata agataaaata aaaaggagtc tgtatttcta tgtattactt
    37921 attaaacaaa agcacaaatc cttactttaa tttggcatta gaagaatatc tatttttaaa
    37981 tgataaatat aatgatgata ttataatcat atggagaaat gaagaatcca tttttatagg
    38041 taaaaatcaa aatccatatc aggaagtata tcatgatgtt attgaaaagg gagaaattcc
    38101 tattttaaga agaatatctg gaggaggaac tgtttatcat gacttaggta atatcaatat
    38161 gtcattcata caaaaagata ggcaacttca tgagatagat tttttggagc atactaagtt
    38221 tatgcaaaag atgctttcaa ccttaggact agatgtatct ataactgaaa gaaaagattt
    38281 atttttaaat gggaaaaaaa tttcaggctc tgcacagtct ataaaaagaa aaaattctct
    38341 ttatcatgga actcttcttt acgattcaga tttaaataaa ttaactaaat atttaaattc
    38401 aaataaagca actgaatcaa atgcaactaa atctgtttca agtaaagtta caaatattaa
    38461 gtttttactc gaaaaagata taaattactt tttagattat tgtgttgaat atttaaaatc
    38521 taatataaag aatataaaag aacttgaatt ggatgaagaa gatattaaaa gtgtatacaa
    38581 tataggagaa gataaatata aaaagataga gtggacatat ggtaaaacgc cgaaatttca
    38641 agtagtgcta ccatttaata atgaaagtaa aataaatata catgttaaca gatggaaagt
    38701 atcaaaattt tttatttctt atgatgataa tgtaattaat atggacaagt tgttagattt
    38761 gaatttcttt aaagaagaaa taaaagagag tattttagaa aattatccac attacataga
    38821 tttaatcaat ttaatatttt aatataaaac ctctaatttg ataaaattgt cttatatcaa
    38881 actagaggtt tttaatattc ttgcatatta acaaccatta caaaattgta aaattaaaaa
    38941 caacactatt gaaaaatcaa tatatattgt aataaatata tgtgtttttc attagcaaat
    39001 agacattaac tatttataca actgaaaatt taatatataa ttaatcagat ggttaaaata
    39061 aaaatattaa aagttttaat aaatgatggt taaaaataaa atacgaggtg ataccatgta
    39121 tagtgttata attgttgcag cgggaagcgg aaggagaatg aacttagata taaacaaaca
    39181 gttcataaaa ttaagagaaa aagaaattat tgctcataca attcaagttt tttatgaaaa
    39241 tataaatata gatgaaatag tggtatgtat aaaaaaagaa gaagaagatt tttttaaaga
    39301 aaatataata aataagtata actttaaaaa tataaaaata gcatatggcg gaaaagaaag
    39361 acaggactca atatataatg gtttaaaaaa attagatgaa aattgtgata tagtacttat
    39421 ccatgatgga gcaagaccat ttgtcgacca tagaataatc aatgaatcta taaaggtagc
    39481 taaagaaaaa aaggctgtgg ttgtaggtgt tccagtaagt gatactataa agatagtgtc
    39541 agatggaaca gtacaagaaa ctccagaaag aaatttgctg tgggcagcac aaacccctca
    39601 aacctttgaa tataatctca taatagatgc ttatgaacaa gcatataaga acaattatta
    39661 tggtactgat gattcaatgt tggtagaaaa tataggtcaa agtgtcacta tggtaatggg
    39721 ttcttatgaa aacataaaaa taactagtcc agaagattta aatatagcag aacaaatatt
    39781 aaatatggaa aaaagagatg aagttaacag tagaaggaga attatatgag aataggatta
    39841 ggatatgatg tacacaaatt aacagaggat agaaaactta taatcggtgg tgtagagata
    39901 ccacacgata aaggtttgtt gggtcattct gatgctgatg tattgataca tgcaataatg
    39961 gattctattt taggtgctct agcattagga gatataggga agcatttccc agatacagat
    40021 gaagaatata agggagcaga tagtatgaaa ttattagaac atgtgtataa tctaataaca
    40081 agtaaaggat ataaaattgg taatatagac agtactataa ttgctcaaag ccctaagatg
    40141 gctccatata ttgagagtat gagaagtaat atatcaaaag ttttaaacac agacattgat
    40201 aatataaaca taaaggcaac aacagaagaa ggtcttggtt ttacaggagc aaaacaggga
    40261 atagcttcac aaagtatttg tttattattg ttgacaagtc agaataatta atatattatt
    40321 agtaataagt ttaatggata tcaagtaata ggcctatata gaatatctat aatgtatgaa
    40381 tttaagtgaa attaatataa atataaaatt agctatgata aagaaatagt aaaatgatga
    40441 aatcttcaca gagagaaaac ggtggtgaga gttttcaaga ggaagtcttt gaacctgtct
    40501 tttagcttaa aggtataaaa atctttacgg taggaaccgt tatattccca aaagagagct
    40561 attcatatag ctaactagag tggtaccgcg gaaattaaac ctttcgtctc tatacttgta
    40621 tagagatgag aggtttttta tattttcagg aagttaatat tcaggaggaa tctattaatg
    40681 aaaatgtcaa aaatgtttat gccgacatta aaagaaatcc cagcagatgc tgagattaca
    40741 agccatcaat taatggttag gtcaggcatg ataaaaaaaa tgacttcagg tgtttataac
    40801 caattaccaa tggggttaag agtgttcaaa aaaattgaac aaataattag agaagaatta
    40861 aataaaaaag attgtcaaga aatactttgt gcagccttac ttccttctga attatggaaa
    40921 gagtctggaa ggtggactgc tatgggtgaa gaaatgttta gactaaaaga cagaacagaa
    40981 agagagtact gtcttgggcc aacacatgaa gaagcattca ctgatataat aagacaagaa
    41041 attacttcat ataaacaatt gccactaaac ttgtaccaaa tacaagtaaa atatagagac
    41101 gagagaagac caagatttgg tgttatgaga actaagactt ttacaatgaa ggatgcatat
    41161 agttttgatg tagatgataa aggtttagat aagtcatatc aagatatgtt tgatgcatat
    41221 gtaagtatat ttgatagatg tggattggag aatagccctg tacaggcaga ttcaggagct
    41281 ataggaggtt ctacatcagc cgaatttatg gttaagtcag aagttggtga agatgaagtt
    41341 gtattttgta gtggatgtga ttatgcagcc aatgtagaaa gagcagaatc ttgtaatcta
    41401 gcatcacaaa aagaagaaat gaaagaatta gaagaggttc atacaccagg agcagctaca
    41461 ataaaagagt tagaagaatt tttaaaaact tctccagata agtttgctaa aactttagta
    41521 tatgaggcag atggaaaaac agttgtagtc gttgtaagag gagatagaga agttaatgaa
    41581 atcaaagtat ctaatgccat aggttctgtt atagaatttg ctcttgctac agatgatgta
    41641 gtgagaaaag taactaatgc agaagtagga tttgcaggtc caataggtat aaatgctgac
    41701 tatgtattta tagataaaga aattgttgaa caaagaaaca tagttgttgg ggctaataaa
    41761 actgagtacc atataaaaaa tgctaactat ggaagagatt ttgaaggaat agttggagat
    41821 tttagaaatg ttcaagaagg cgacaagtgt atagtatgtg gtaagccact tgaaatagct
    41881 agaggtgttg aagtaggaca tatatttaaa ctaggaacta agtactcaga atctatgaat
    41941 gcaaacttca tagacaaaga tggaaaatca aagcctatag taatgggatg ttatggaata
    42001 ggtgttgaaa gaacagcagc agctataatt gaacaacata atgatgagaa aggtataata
    42061 tggcctttgt cagtagctcc ataccatgtt gtgatagttc cagcaaatat gaaaaatgaa
    42121 gaacaaatat caatagctga aaatatatat aatgatttgc aagctatggg tgtagaagtt
    42181 ttattagatg acagagatga aagaataggt gtcaaattca atgattcaga attaatagga
    42241 atacctatga ggattacagt aggtaaaaat attaatgaag gtaaagtaga atttaaactt
    42301 agacataaag aagataaaga gataattgac atagaagaaa taaatgaaaa agtaaaggca
    42361 gagtttatca ggaataatgt taggttagga taataactta aataagatat tgtatagata
    42421 atcaaagttg tactttatag acaccatttt atctatatat aaggatataa aatggtgttt
    42481 ttttataaaa caaataaatg aggaggtaat taaaatggca aaaaatgaaa aacaatttgt
    42541 tgaagaaata acaaagatgg aagatgattt tccacaatgg tacacagatg taataactaa
    42601 gactgactta gttgattatg caccagtaaa aggttttatg gttgtaaagc catatggata
    42661 tgcattatgg gaaaagatgc aagaatttat ggataaaaaa tttaaagaaa ctggacataa
    42721 aaactgttat tttccattat taataccaga gagtttatta aacaaagaag cagaacacgt
    42781 tgaaggtttt gctccagaag ttgcatgggt aacacatgga ggaaataaaa aattagaaga
    42841 aagattatgt gtaagaccta cttcagagac tataatatgt acaatgtatg cgaaatggtt
    42901 aaaatcatat agagaattac catatcttta taatcaatgg tgctcagttg ttagatggga
    42961 aaaatcaact agacctttct taagaacatc tgagttttta tggcaagaag gtcatacgtt
    43021 acatgaaaca gcagaagaag cacaagaaga aacaatacaa caattagaag tatataaagc
    43081 gctatgtgaa gaattacttg caatgccagt tgtagctggt caaaaaagtg aaagtgaaaa
    43141 atttgcaggt ggtgaaagaa catatactat agaagctatg atgcatgatg gtaaagcatt
    43201 acaatcaggt acaagtcact tcctaggtca acactttact aaggcttttg atattacttt
    43261 tgcagataga gaaggaaatt tagctaatcc atatcataca tcttggggag catctacaag
    43321 acttataggt ggacttataa tgactcatag tgataacaga ggtttagtat taccaccaag
    43381 agtagctcca attcaagttg ttatagttcc tatagctgct aaaaaaggaa atgtaatgga
    43441 gactgttgat aaaatatatg ctgatttaaa agctaaggga gtagctgtag aagttgatga
    43501 tagagataac tatacaactg gatggaaatt taatgagtgg gaaatgaaag gtgttccagt
    43561 aagagttgaa attggaccaa aagatataga aaataatcaa gctatggtat ttagaagaga
    43621 tactttagaa aaggattcta tgcctttaga aggattagct gatgctatat gtgatttatt
    43681 tgatgttata cacaatgata tgtttgaaaa agcaagaaaa catagagaag acaatacatc
    43741 tatagttgaa aatatggatg agtttagaaa agctttagaa gaaaagccag gattcataaa
    43801 gactatgtgg tgtggagatg cagaatgtga agctaagatt aaggaagaaa caggagcaac
    43861 tataagatgc ttaccttttg aacaagaaaa cttaggtcac aagtgtgtgt actgtggaaa
    43921 agaagcagat agtatggtag taatggcaaa agcttactaa aatacattta aataaaaact
    43981 ggggtagaaa gtatttaata ctttatccca gtttttttgt tttttatgag taataaaatg
    44041 tatttgtaac tatgtcataa gataagtcat agatacttat attaaaaaga atataataga
    44101 gaactatttt taataattac atattaatga aagcaaaata tttttgttat atagattttc
    44161 aataaagcaa acaataaata taaatgaata ttagtaagga gtgcttttaa tttttagaaa
    44221 ataaatgact taaaagaaag atttatgaaa ttaaaactag gattttctga tataataaac
    44281 atgtgtattt ttaaataaaa aggatattat tattagattt gattaaaaat aaacttgcaa
    44341 aacaatgtac tagtttaata ttatagttat attgaataaa atatcaggag gaagtaaaaa
    44401 tgaatgtaag agtaaggttt gcaccaagtc caacaggatt tgtacatata ggtagtttga
    44461 gaactgcttt atataactat ttatttgcaa aaaaaatggg cggagaatat atattaagag
    44521 tggaagatac agaccaaagt agattagtag aaggtgctat agagaatatg cttaatgcta
    44581 tgaaatgggc tggggtcaac catagtgaag gtgttatatt agatgatagt ggaaaagtag
    44641 tacaaaaagg agaatatggt ccatatattc aatctcaaag attagatata taccaagaat
    44701 atataaagca acttttagat agtggaaaag cttattactg tttctgtaca aaagaaagac
    44761 tggatgaagt aagagatgct caaagagcag caggagaaac agctaaatat gatggtcatt
    44821 gtaagaatct ttctaaagaa gaagtagaag cgaatataaa agcaggaata ccatatgtta
    44881 taagattaag attgccagag aatcatacaa ttaagtttac agacttagtt agaggagata
    44941 tggaatttaa tactaatgac ttagatgacc aagtattaat gaaaacagat ggatttccaa
    45001 cttatcattt tgcagtagtt gttgatgact atttgatgaa aattacacat gttataagag
    45061 gagaagaatg ggtatcatct actccaaaac atgtttattt atatgaagct tttggatggg
    45121 aagcacctgt atttgtgcat ttaccaaata tacttaataa agaaaagaaa aaattaagta
    45181 aaagacaagg tgatgtagct gttgaagact ttaagaaaaa aggatattta ccagagggat
    45241 tagtaaacta tgtagcatta gttggttggt ctcctgaaga taatcaagaa ttgtttacaa
    45301 tggaggaatt agaaaaagcc ttctctgtag aaagagtctc taaaagtggt ggagtatttg
    45361 atactgaaaa attaaattgg gttaatcagc attatataaa agatggtgat gatgcttatc
    45421 taacagactt agcaatacca tttttaatag aagatggatt tataacagaa gaagaagcta
    45481 ctaataaata tgatttctta aagagtatga tatcagtact taaagagaaa ttacaatatg
    45541 taaaagaagt tactgaacat gcaagtatat tttttggaga taaaatagag gtagaaactg
    45601 aagagggaag agagttctta agattagaac atatacctac tttaatagat gctttgagag
    45661 aaaaaataga aaaaacagag gtattaaatg ctgagtttgt tcaagctatg cttaaagaaa
    45721 tacaaaaaga gtacaaaata aaagggaaaa atttatttat gggctcaaga ataattttga
    45781 cagggcaaat gcatggtcca gatttaccaa aagtaatgga agttttagga aaagaaactt
    45841 gcttaaatag aatagcttat gtaaaaaata atatattata gtcataaaag tccgctaatt
    45901 tagaagcgga ctttttttgt gttagtattt ggtgaaaata tctgcttaag aaaatgaagg
    45961 tatttaaggt aataaattta atatataaaa agcaaagcaa aaatataaat aaaatatgaa
    46021 taataaacta ataaaatatt aagcatagaa gaagggaatc tattatttta gtttgattta
    46081 attattaagg gggtaattac tatgtatagt aatattgatg atgttaaaaa ggaattaaag
    46141 gagctatgct tagaatatgt tacaatttta gaaaaattaa aagatgaaaa aatgattaca
    46201 gaagaaactt ttgaaaagtg ctcttctcaa aaaaaaatat ttttagaaga acaatagagg
    46261 atggtaatag tattattatt atgtagtttg aaagatagta cgaaaaatga tagtaatact
    46321 attatttatt gcaattttca actataatat aatatataat gttaagaaga taatttataa
    46381 aaatacagtg aggtgatgag tgtgaaagtt tataatacat tgactagaac aaaagaagaa
    46441 tttgttccat tagaagaagg aaaggtaaaa atgtatgtgt gtggtccaac agtttataac
    46501 tatatacaca taggtaatgc aagaccattt ataatatttg atactctaag aaggtattta
    46561 gagtatagag gatatgatgt aacttatgta caaaacttta cagatgttga tgataagatt
    46621 ataaatagaa gtcatgagga gggaatatct cctgaagaag ttgcggctaa gtatataaaa
    46681 gaatattttg tagactgtga tgggctagga ataaaaagag ctactgttca tcctcaggtt
    46741 acagataata tacaacagat tatagagttt ataaaagagt tggaagataa gggatatgca
    46801 tatgcagtaa atggtgatgt atattttgat acaaataagt ttgaaggtta tggaaaactt
    46861 tcaggtcaaa aacaagaaga tttagaggca ggggctagaa ttgaggttaa tgaccaaaaa
    46921 agacatccta tggactttgt tctttggaag gcaaaaaaag aaggtgagcc aggatgggat
    46981 agcccttggg gagaaggtag accaggatgg catatagaat gttctgttat gtctaagaga
    47041 tatttaggtg aaacaattga tatacatgca ggtgggcaag atttaacatt cccacatcat
    47101 gaaaatgaaa tagctcaaag tgaagctaga agtggaaaaa cattctcaaa atactggatg
    47161 cataatggat atataaatat aaatgatgaa aagatgagta aatcaaaagg taatttcttt
    47221 acagtaagag atatatcaaa attatatgat ttagagatag taagattttt catgttatca
    47281 gcacattata gaaatccagt aaactttagt gatgagatgt taaatcaagc taaagcaggt
    47341 cttgaaagac tatataatac taaagaaaaa ttagaattta cgctaagtaa tttagtagaa
    47401 tctcctttaa cagaaaaaga agtagagctt gttaaagaat tagatgactt tagacaaaaa
    47461 ttcatagatg ctatggatga tgatgttaat acagcagacg cagtaagtgt aatatttgaa
    47521 ttagctaagt taataaattc taatgtagat gaaaattctt ctttggagtt tgctaaaaaa
    47581 tgcttagatg aatttaatga acttacagga gtattaaata ttgtaaataa gaaaaaagat
    47641 actgtattag ataaagacat tgaagaattg atacaaaaaa gaactgatgc aaagaaaaat
    47701 aaagagtttc aattagctga tgatattaga caacaattac tagatatggg aattgtatta
    47761 gaagacacaa gacaaggtgt taagtggaaa aggatataaa aatggaaaaa actgaattag
    47821 ttactatgtc accattagtt ttagcatact taggtgatac agtgtatgag acatatataa
    47881 gagaatattt aattagacag aatacacaaa gaaaagttaa tgatttgcat aaactagcta
    47941 taaagtatgt aaaagctaaa gctcaggcaa ctataattca tgaaattgaa attgagttaa
    48001 ctgaagaaga gagtaaaatt tataaaaggg gaagaaatca aaagtcaaat acttctccta
    48061 agaatgcaga tattatagac tacaaacatg caactgggtt tgaggcatta gtgggatatt
    48121 tgtatttaaa taatgaaata gagagacttc aatatattat caataaagga atcaaaatta
    48181 ttgaaagaga tatgtaaata ttaaagagtg ttgtcttaat aataagtaat aaggcaacac
    48241 tttttttata actaatgtat aataaatata tagaaattag taatgagaaa ggataaaaag
    48301 ttatgaaagt aaaattaata tcacatacac ctgaaccaga aaaagtaata gctatggcag
    48361 ctaagctatg ttattcacca gttgggacag acgaaataga aaaagactta acagatgaaa
    48421 gtatagagaa atttttaaat atgttattaa gtataggtca tgggtcaata ttagaacatg
    48481 cttcatttac attttcaata gaaggtattt caagggcttg ttcacatcaa attgttagac
    48541 atcgtatagc tagtttttca caacaaagtc aaagatatgt taaattagaa caatttgagt
    48601 acataattcc tccagaaata gaaaaaatag aaaaggcaaa agagttattt atagactcca
    48661 tgaaaaaaga ccaagagaat tatgataagt tagttgaaat attgtttgaa aatcattata
    48721 atgacctaat aaaaaacggt aaaaatgaga aaacagctaa aagacaagct gaaaagaaag
    48781 caatagaaga tgctagatac gtatttccaa atgcatgtga aacaaaaatg gtatttacta
    48841 taaatgctag aagtttgttt aatttctttg aacatagatg ctgtgaaaga gcacagtggg
    48901 aaataagaaa tttagctgtg gagatgttaa gagaggttaa aaaggttgct cctatattat
    48961 ttaaaaagac cggtccaagt tgtgtaaatg gaagttgtcc agaaggaact atgacttgtg
    49021 gagatatagt tcaagttaga gaaaaattta aggccttgta ggaggtgaat aatttggcga
    49081 gtatagaagg aagaaatccg gtaatagaag caataaaaag cgacagagaa atagataaaa
    49141 tattaattgc aaattcagct aaagaaggtt caattaagaa aataatagga atggctaaag
    49201 ataagaatat aattattcag tatgttgata aacataagct agatgaagta agtacaagtc
    49261 attcacatca aggtgtaata gcttatgcaa gtgagtataa gtattatgaa ttagatgagc
    49321 taatagattt agcaaagaat aaagatgaag acccattttt cattatatta gatgagataa
    49381 cagacccaca taatttgggt tcaataataa ggacagcaga tgcagtagga gcacatggag
    49441 ttatcattcc aaaaagaagg tctgtacaca taactcctgt agttgccaaa gcatctgctg
    49501 gagcagtaga atatatgcca gtttgcaagg taaccaatat agttaataca ataaaaagac
    49561 tcaaagaaga agggctgtgg attgctgcag ctgatatgga tggagaaact ttttataaac
    49621 aaaatcttac tggtcctctt ggtgtagtaa ttggaagtga aggttttgga atatctagat
    49681 tggttaaaca aaactgtgac tttatagtaa aaatgccaat gataggtaat gttacatctt
    49741 taaatgcatc tgtagcaggt ggaatacttt tatatgagat attcagacaa agactggata
    49801 aaagtaaata ggcatgaaaa aaaatataaa tcattactta ataatagatg gctacaatat
    49861 tataaatgcg tgggacaatt tgaaagaact ggctaaagag gacttagaag attctcgaga
    49921 aaagcttatt gatgacatta tagaattttc tgagtttatg ggttataaga ctataatagt
    49981 ttttgatgct tataatgtta aaaattctcg agaaaaagtt gaaaaaagaa aacacataac
    50041 aatagtttat acaagagaac accaaacagc agatagttat atagagaaat ttataacttc
    50101 tttatcaaag tatgatgatg taaaagtagc cactaatgac tatgcagaac agcaaatgat
    50161 tttaggaaaa ggtgctacta gaatgtctgc aagagaatta aagttagagt tagatcgttc
    50221 caagaataaa atgaaggaaa aaaatatcgg tttgaggaaa aaaattcagc gaaattggtt
    50281 ggaggaaagg ttagataaag aaacattgtc gaaacttgag aacattcgta gaaagcgttg
    50341 aaattactag gttctttaga ctataatata cctataaatt tgttttatat atgggggaga
    50401 tttacatgtt ggtagcaaaa gaaaaaagtt atgagttagt ggacaattgt cagcaggatg
    50461 agtataacat tgtattaaga gcaagtgaag gggataaaat agcactagag tacattatta
    50521 ctaaatacag aaattttgta aaggcaaaag caaagtcata ttttttaatt ggagcagata
    50581 aagaagatat aatacaagaa ggaatgatag gcctttataa ggcagttaga gattttgatg
    50641 gaagtaagac caattcattt aaatgttttg cggagatatg tataacaaga caaataataa
    50701 ctgctataaa aactgcaaca agacaaaaac atataccttt aaattcatat gtttctttga
    50761 ataaaccaat atatgatgaa gagtcagaca gaacactttt agatattata gctacaagta
    50821 tagtaacaga tccagaagag cttataatta gtaaagaaga gttaaaaaat atagaatcaa
    50881 aaatgaacga attgttaagt gacttggaat tagaagtact agaattatat ttaaatggaa
    50941 agtcatacca gtttatagcg gacaagctta aaagagatgt aaagtcaata gataacgctt
    51001 tacaaagggt taagagaaaa ttagaaaaac atcttgaaaa cagaaatgat taatagtaaa
    51061 atacttacca taagcttatt gtgagcaaaa ttaatttata tcgaaagata agggaggaaa
    51121 ttcaaaatgg ctaaagctaa atacgaaaga acaaaacctc atgttaatat agggacaata
    51181 ggacacgtag accacggtaa aactacatta acagcagcaa taacaaaaac attatatgac
    51241 agatatcaat taggagaagc agtagatttc gcaaacatag ataaagctcc agaagaaaga
    51301 gaaagaggaa tcacaatatc aacagcacac gttgagtatg aaacaccaaa tagacactat
    51361 gcacacgttg actgcccagg acatgctgac tacgttaaga acatgataac aggagcagca
    51421 caaatggatg gagcaatatt agtttgttca gcaacagatg gaccaatgcc acaaacaaga
    51481 gagcatatac tattatcaag acaagttgga gtaccatata tagtagtatt cttaaacaaa
    51541 tgtgacatgg tagatgatga agagttatta gagttagtag agatggaagt aagagattta
    51601 ttaacagaat atgatttccc aggagatgac actccaatag taagaggttc agcattaatg
    51661 gcattagaag atccaaagag tgagtgggga gataagatag tagaattatt cgagcaaata
    51721 gatgagtata taccagctcc agagagagat acagataaac cattcttaat gccagtagag
    51781 gacgtattct caatcacagg aagaggaaca gttgcaacag gaagagtgga aagaggagta
    51841 ctaaaagtac aagacgaagt agaattagta ggattaacag aagcaccaag aaaagtagta
    51901 gtaacaggag tagagatgtt cagaaaatt
//
LOCUS       DAEPHU010000022        50379 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 01A10CD0081
            SAMN05941466-rid12468953.denovo.022, whole genome shotgun sequence.
ACCESSION   DAEPHU010000022 DAEPHU010000000
VERSION     DAEPHU010000022.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941466
            Sequence Read Archive: SRR6291087
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 50379)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 50379)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068158.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 22:43:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,892
            CDSs (total)                      :: 3,805
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 87
            rRNAs                             :: 8, 1, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 55
            CDSs (without protein)            :: 55
            Pseudo Genes (ambiguous residues) :: 0 of 55
            Pseudo Genes (frameshifted)       :: 21 of 55
            Pseudo Genes (incomplete)         :: 28 of 55
            Pseudo Genes (internal stop)      :: 16 of 55
            Pseudo Genes (multiple problems)  :: 8 of 55
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..50379
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941466-rid12468953.denovo.022"
                     /strain="01A10CD0081"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            303..953
                     /locus_tag="KR231_001388"
     CDS             303..953
                     /locus_tag="KR231_001388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HBH0003772.1"
                     /translation="MDFISSILQGLLSILFNFTGDFGISIVLITLIVKLVLMPLSLKQ
                     RFSVKKQQELAEKMEYIKEKYKNDTKELEKQIQVSSVESMKSMLGCLIVLVQMPVVYA
                     LYHVCLDMTKEFTTIIIPWIANLGTFDNLFILPCIYTLIMLASNLVNYIPYLKINSQV
                     KFNKQMAVVTTITSLILTVRTPVAIGLYFITSAIYSLIEDICFRIYFNRKNRIVTK"
     gene            1156..1827
                     /locus_tag="KR231_001389"
     CDS             1156..1827
                     /locus_tag="KR231_001389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBH0003773.1"
                     /translation="MAKILVVEDEKRMQNIIVEYMQKGGYTCITADDGVEALTILKSN
                     NIDLMILDIMMPYLDGFSVCRVSREMTNIPIIILTAKGEEEDKLKGYEYGADDYITKP
                     FSPKVLLAKVNALLRRYTTDIPKNSLSLGKIFIMVASRQVYVEDKLIDLTYKEFELLR
                     LFMENPNQVFSREKLLNCIWGYDFEGNTRTVDTHIKTLRKKLGSEGHHIVTLIRSGYK
                     FEVKE"
     gene            1824..2954
                     /locus_tag="KR231_001390"
     CDS             1824..2954
                     /locus_tag="KR231_001390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBH0003774.1"
                     /translation="MNSLRKIIEKLKNVDISNWIKQNFGLYSVRKKVFLLSKLSGALI
                     ILFYLVVEEFSINSKFEFWIWFIILVIFIMSIDFLLGKFISEPITSINKSAKSMSQLD
                     FSNPCTVNTNDEFGELSRSLNTMSTNLQQALSDLESANIQLEKDVNKERMLLEQRKEL
                     VDTISHEMKTPLGIIRAYTEGLIDEVDEEKKKNYMNVIIEETDRMNNMIVSLLDLSAL
                     EAGVSKLNPERFDFIEFVETVAGRLLIDIPDANFYFTYDLPEYEVFVVADKMRMEQVV
                     ENLVINAKKHVVYNGNLDLSITCENGLLLFEIYNDGRFIEQDEISKIWSKFYRSVQSQ
                     RTGGSGLGLAIVSQILTMQGLEYGVNNRDRGVEFYFMIPIDE"
     gene            3385..4230
                     /locus_tag="KR231_001391"
     CDS             3385..4230
                     /locus_tag="KR231_001391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH0003775.1"
                     /translation="MIKVRELKFSYGKDKQILHGLNFEVKEGEIFGFLGPNGSGKSTT
                     QKILNGVLKGYNGHVSIFGKEVKAYTESLYQKIGVLFEFPYLYTNLSAIDNLEYFSSF
                     YPKNQRRDIYELLDLLEFKKEFINKPVSSYSKGMKQRISMARALVSNPKLLFLDEPTS
                     GLDPSGAVLFRKIIEEERKKGTTIFLTTHNMLDADLMCNNVAFIADGKIMVIDKPKNL
                     KMKNSNNKVEVEFVYNGNRDIEIVDIQELESGITFKYDEILSVHSKEPTLEEVFIKYT
                     GRMLV"
     gene            4230..5258
                     /locus_tag="KR231_001392"
     CDS             4230..5258
                     /locus_tag="KR231_001392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBH0003776.1"
                     /translation="MYSKFFTLVKKDFWMMIYGKFFVLTLGSLILYSCYINFGYVKFM
                     DEDSYHNNVYLYNPENISMSASPLINQVSSIGELKAKLDEDTSAVCIDMSSSKPKVIL
                     HESIKGVDNYRADYALSLLSSEKDHNSKISDNNAIIQINDKDTSEIKQRKDMTCEILF
                     FEIVAIGFLGIASLLFKEKQMGVMRITGILPVKRSLFILSKIFAFFICDLCFTVLLVV
                     FNIGFLEGIKILPQVLVQASILSIIMSLIGIGCSMLLRDFKQFSLIYLVVAVFITTPI
                     FLSANTSFEIDWIKYHPFYHVYSQLKNAFFMNFSKELVYFVVCSLTIIVLFLLVKYIF
                     NKELVREG"
     gene            5261..6274
                     /locus_tag="KR231_001393"
     CDS             5261..6274
                     /locus_tag="KR231_001393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBH0003777.1"
                     /translation="MIGLRYQLKSIKKDKMCIISFFLPVVMAILINFMGTIDISSLGE
                     IRFGIVKDTLPVQTEQWLKKYGMVSVYDTKMHLIREIKDIKTDTIGVVRDGKGIKTVF
                     YGNEINAIKNVGKTLPEMFRLKGDLKDVEVTILPKDSILKEFQNVFIAMILITAMFMG
                     CTFNAMNIISEKEDGISFINEVLPQSRSQYIIQKVFLGLLCGCLSSMITVFICLDISI
                     LDMIMMLLLVVFSAFISSLIGLFIGKLSEGLMVGIVYIKIVMILFIGTPLLIYLLGVN
                     TSGIGNLCYIMPSVATFNGIMEIINGNVIIIKDIVILAVHCVVWFMIYIILDKKRKLS
                     FSR"
     gene            complement(6791..8041)
                     /gene="cme"
                     /locus_tag="KR231_001394"
     CDS             complement(6791..8041)
                     /gene="cme"
                     /locus_tag="KR231_001394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter Cme"
                     /protein_id="HBH0003778.1"
                     /translation="MENKNTNSTWKKKVILFLASQYISLFGSSLVQMAMIWYVTLQTS
                     SGVWVTVLTVCSFIPQMIISFFAGVWADYYNRKVLIIVSDSTIAISTLVLILFMMSSN
                     GTTSELIAISVISVIRSLGSGVQTPAVNAMIPQLVPEEHLMRFNGINSSLQSIVQFIV
                     PIVAAAILGFGNKINQVLLIDVFTAIIAIVLLIFIKIPKHDIPKQTEKVSFFADMVSG
                     IKYCFSDKFIRKVLFTYGAFMLLCVPSGFLIGLLIERTFGKGYIYLSIIEMIGFLGMV
                     LGGLIIGVFGGFKNRNKTFFLAILSYAIFSIILGLVTQAWQFFIFMFFTNFSIPIIQA
                     SAMTMLQEHVAPQMLGRVLSLPIIIYTGFIPLGMMIFGPMADVISINNLIIIAGIILL
                     FFALAIPYSKQFYKQGISKSNESE"
     gene            complement(8127..8873)
                     /locus_tag="KR231_001395"
     CDS             complement(8127..8873)
                     /locus_tag="KR231_001395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HBH0003779.1"
                     /translation="MDTYTTSEVADLIGVHPNTVRLYEELNLIPKPKRNTNGYRIFND
                     FHIEQFRFARTALKIEVVQRGLRKDALEIVRTSANRDFDKAISLVNQYLQQLEIEKSN
                     AEEALTIVAQILNGNTPETNKLFLTRKETAEHLNVTIDTLRNWEMNGLLKVKRKQNGY
                     RVYTDEDIKRLKIISALRCANYSLSAILRMLNALSSSPNTNIKTVLDTPKDDDEIISV
                     CDKLITSLKEAEHNAKTMKSHLQIMKKQFS"
     gene            complement(9026..10048)
                     /locus_tag="KR231_001396"
     CDS             complement(9026..10048)
                     /locus_tag="KR231_001396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydrolase"
                     /protein_id="HBH0003780.1"
                     /translation="MNKNNCLDLIFEKVDPSSVGMSSEKLSQLEPLIISQYSNINGII
                     IARKGKIVFEKYYNGYNADDTFHVASVTKSIISALIGIAIDKGYIKDVDQKVVDFFPE
                     YTCSPSEICKKAVTIRHLLTMTAPYPFKNMTESLERLCKQKDWIKYTLNQLGQKGEIG
                     TFKYSSAGTHLLSAIITKTTGKSAREFANEYLFKPIGMKVIPDYDMKDFGFEDFFGKN
                     LKGWAKDRQGYSIGGWGLTLSARDMLRFGFLYLNDGIWNNKRIISKSWIEESVKMNSN
                     EYGYLWWLCKKDGVLWYSAMGTGGNAICCIPQYDLVIAIPSKIVFKPRDRWEFIEKYI
                     LTSIID"
     gene            complement(10048..12468)
                     /locus_tag="KR231_001397"
     CDS             complement(10048..12468)
                     /locus_tag="KR231_001397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrA"
                     /protein_id="HBH0003781.1"
                     /translation="MKEIKINGAKIHNLKNIDVSIPKDKLVVATGVSGSGKSSLMFDI
                     VFEEGRKQYLQSLGILAGIDSEDKFDNIQGLAPTIAVQQNIIRQSNPRSTVGTRTNIL
                     NMLTLLYSVEGQIMCTMCDTPVSDNLICNNCGYEEERLRPSYFSYNSSDGMCMKCSGH
                     GAYFEINIEKLVLDKHDTLKQVLDRAKITPGYLRVFSKKFNDYLDIQFLQLPEEIRNE
                     VLYGHYENGKKSSSLSKVFHNRYKRGEDLNGVYTMTACSDCNGFKIGEEARRVLLNGK
                     HIGELGKMTILEIDDFLKLLINQGNLNTFGTNLVNDILSKTQHLIESRLGHLSLYREM
                     STLSGGEMQRLFLNSHLDSEMDSLIYVLDEPTAGLHESEKIDILKSLKKLKDLGNTVI
                     VVEHDKNTIEMAEHIIDIGPKAGVEGGQLVYQGDLEGLLQSDKSLTGQYLSGKYPMPN
                     RTSNKNITHTDKIPCITIQNANTNNLKNVTVSLPLGAMVGISGKSGSGKSSLISDTLL
                     PLLRSQFNNHTINNQINSSESEIGEEDDYAVVETIADRLIGTKHISGYSEISQSPIGK
                     NMNSTPASYIGIWDKIRTLFAGQPESLEQGFTAGHFSFNSKGACPKCSGSGYEKVWLG
                     NNLSIDHICSECQGKRFNDESLSIKYKNKNIHDILNMSVSESVHFFKDIPNIVSHLNV
                     LEQIGMGYIKLGQPTPTLSGGESQRIKLAKEIGKKRNGNILYVLDEPTTGLSLYDTSK
                     LIQLLDELVENGNSVIVVEHDIDVLNVCDWIVELGPEGGDKGGYIIAEGSPKTLKENP
                     KSITGRYL"
     gene            complement(12554..13474)
                     /locus_tag="KR231_001398"
     CDS             complement(12554..13474)
                     /locus_tag="KR231_001398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HBH0003782.1"
                     /translation="MTNAKSKKEYLNRICKVQDYIEEHLHEPLSLDELSNIAGFSKFH
                     FHRIFKAIEKETLAQYVNRLKLENATAFLIHRTDMTVTDIAHYFGFTDSAVFSRAFKN
                     YYKISPIKYRNNYSKNCKEPYKISQYNRSISKPKCKNTREVKGEIEILELDNMNTIYT
                     RYTGSYGNLTSTFPKLLERLFTYASEQNLLGLENTQILAIYHDNPQFTQEHQLRTSIC
                     MTIPDNIVVKENDNLGNMIIPSGKYLVGHFDISKSEYSDAWDFMYNEWLSNGNYKLRA
                     SFPFEVYLNNPHNHPQNRHLVDIYLPIEPF"
     gene            14064..14990
                     /locus_tag="KR231_001399"
     CDS             14064..14990
                     /locus_tag="KR231_001399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conserved phage C-terminal domain-containing
                     protein"
                     /protein_id="HBH0003783.1"
                     /translation="MSNSFYQLNSAVLYFNEKRDVNRIRFNHYVMRKENIQRLKGTLP
                     RGQFMMTVRKAASDLDVSISTISRLVNEFIDLGILRLISRGVKGNCCSVYSYVCSESS
                     NAEIVTKNGDIFKNIEKYIDATINNNQKTMKYKHRNELFKNSNTNIYSRINQESIDKD
                     YDLIIHTGYETENETKKKELLKNNLNKKNLNKNTFENSDEDLTEDSTYKNPESIHEII
                     IRKLNSESGKNFKADLSITKALIDKRLKEGYSLEDFYKVIEAKVRRWRYTDMEIYIEP
                     TILFGYEFESYLNEESSLSACNYGDMCYEDMY"
     gene            complement(15373..17025)
                     /locus_tag="KR231_001400"
     CDS             complement(15373..17025)
                     /locus_tag="KR231_001400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp21"
                     /protein_id="HBH0003784.1"
                     /translation="MNKKNLAILISGMMFFSSSSAIFADNTTKQERLIGKTRYETAVE
                     VSKLGWVQSKTAIIVNGNSIQSALCANPFAKLKNAPILLVNNNSIENSTKAELKRLGV
                     DNVYIVDSGNSISSKVENEIKSLNIKINKIVGNNIYEMSTNVLKEIDKIKKIENVAVV
                     NGLKGLSDAVSIASPAAIHNMPIILVSDENSNDSSINFLNNRSIKKSYIVGGNKILSD
                     NTVKKYPNRERISGSDRNNTNAKIIDKFYKDKKINNVFVAKDGINQENALVDSLSIGV
                     LAAKENSPIMISNGSLVNSQKEFIKNKDIDEITQVGGGYNQKAFEDILKLKNVNIRNK
                     TKKISLIQAKEILKQALPGSNILVCYYDEDDNEYDCKVIKDNILYEIEIDAYSGKIIE
                     IEKDDDLNDNNLGTQNISLDKAKSIALDAIPNGNLIYCKYDAEDNEYEAKVIKNKKTY
                     ELEISAFDGRIVDIDMDNDSDDDFDDNDKNNSNTNDNSSIISAEKAKSIMLDKVPGGK
                     IVKFKYDEDDKEYEGEIIKGKTEYEITINAITGKILEFEIDD"
     gene            17624..18745
                     /locus_tag="KR231_001401"
     CDS             17624..18745
                     /locus_tag="KR231_001401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434286.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HBH0003785.1"
                     /translation="MEAKKLGFGLMRLPIKDENDVTTIDMEHLNKMVDTFLERGFTYF
                     DTAYVYHMGKSEIALRESLVKRHKRESFTIATKLPLMALKKKEEQETIFNEQLEKCGV
                     DYFDYYLLHNIGVSHYEVAKKFDSFKFIEEKKKEGKIKNIGFSFHDSAELLDKVLSEH
                     PEVDFVQLQINYLDWDNESIQSRKCYEVAEKHNKPVIVMEPVKGGTLAKIPEKAEKLL
                     NDYNPDMSISSWAIRFAASKDNVMMVLSGMSNMEQLLDNTGYMQNFKPFVQEEYNIID
                     EAVEIINESILIPCTACQYCVEGCPKNIAIPNYFALYNAEKQALNTGFSTQMVYYNNY
                     TKTYGKASDCIECKQCEESCPQHIKIIDALKNVAETFEK"
     gene            18781..19194
                     /locus_tag="KR231_001402"
     CDS             18781..19194
                     /locus_tag="KR231_001402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HBH0003786.1"
                     /translation="MTISEVSKKYELSADTLRYYERIGLIPPVNRNKSGIRSFTEEDC
                     EWVNFIKCMRGAGLSIETLIEYVAMFQQGSSTIKARKELLIEQRNQLAKRIEEMQKTL
                     ERLNFKIDRYEEGIIEKEKVLKSSRNKKMEAVSYE"
     gene            19187..19726
                     /locus_tag="KR231_001403"
     CDS             19187..19726
                     /locus_tag="KR231_001403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin family protein"
                     /protein_id="HBH0003787.1"
                     /translation="MSKNVLIVSASPRKGGNSDLLCDQFIQGVLESKNQVEKIFLKDK
                     DINYCTGCGACYEKEANCSQTDDMGEILEKMIGADVIVLATPVYFYTMNAQMKTMIDR
                     TCSRYTEICDKDFYFIVTAADENVADMERTIEGFRGFTSCLNGSKEKGIVYGVGAWNV
                     GDIKGSKAMKQAYEMGKLA"
     gene            complement(19926..20411)
                     /locus_tag="KR231_001404"
     CDS             complement(19926..20411)
                     /locus_tag="KR231_001404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0003788.1"
                     /translation="MSKSELTAETTEEMLEVLSGKDYDIACHLHELGKSLDCKIEPKT
                     GARSYKIVYSTKKPKRSLFTIECNEKKWRVKANLFHLNTYKDAVEECSKTIKDSITKT
                     RTCKKCNSKCIGGSSFELDGKSYLTCIGSGHYFANMEEMDWKNLEKLITKENNIMQES
                     V"
     gene            21316..21693
                     /locus_tag="KR231_001405"
     CDS             21316..21693
                     /locus_tag="KR231_001405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003483933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RidA family protein"
                     /protein_id="HBH0003789.1"
                     /translation="MSKVVIATEKAPGAIGPYSQAIQVGNIVSTSGQLPIDMKTGELV
                     SDPKEATKASLDNVKAILEQAGTSMDKIFKTTVFVKDLKDFNDINEVYATYFKENPPA
                     RSCVQVAQLPKDAVLEIEAMAVL"
     gene            22089..23894
                     /locus_tag="KR231_001406"
     CDS             22089..23894
                     /locus_tag="KR231_001406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HBH0003790.1"
                     /translation="MLSKLKEFQQEMIKYTETVASVLDVDIEIVDDRLIRISGTGLYK
                     SKINESVVTEGFIYDNVIQTGQELVVLDICDNQLCIECSHYMKCLNKVIIAVPIKYNN
                     RTIGVIGAISTDKTKKVEISAKIDNYLKFVNHICDLISMKIEEHEASKNSSRKMDMMI
                     EIIENVEKGVIILDINSKISYINNIALKKLDIDKNIIENIVNIVSVESSSNGHELLEI
                     DIDNKIYNINAKIIPVYPYINQYDKIIIFDKTYINHKGHGKVNSGWGNSDIESIIGNS
                     EAMLKVKERTKKLAKSNSTVLITGESGTGKELIARAIHAEGSRWNKPFIAINCAAIPE
                     NLLESELFGYIKGAFSGASSGGKVGKFELANEGVIFLDEIGDLSMPLQAKLLRVLQER
                     KFARIGSNKLIDLDIRVIAATNKNLLKLVNEGKFRDDLYYRLNVIPINLPPLRERKDD
                     IEAIMMKFASKYSLELGIQLNKIEENVMNMLINYNWPGNIRELENAVEYMMNLVGDDG
                     IIYKDMLPLDILNYYNINGNIYKNKDVNIIFEDDIVGGIVENQERILSIKELELTYIN
                     KLLNKYGRDTKTKKKIAKDLGIGLATLYRKLEEEQ"
     gene            23971..24508
                     /locus_tag="KR231_001407"
                     /pseudo
     CDS             23971..24508
                     /locus_tag="KR231_001407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427977.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="2'-5' RNA ligase family protein"
     gene            25122..26336
                     /gene="dpaL"
                     /locus_tag="KR231_001408"
     CDS             25122..26336
                     /gene="dpaL"
                     /locus_tag="KR231_001408"
                     /EC_number="4.3.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopropionate ammonia-lyase"
                     /protein_id="HBH0003791.1"
                     /translation="MREIKWKLNNLPKSEEKEKGIEFLKDEEIAKAKAFHESFPQYEK
                     TPLVKLDNLAKSLGVSGIYVKDESYRFGLNAFKVLGGSYSMGRYLAQRLNTDISELGY
                     DKLTSKEIKEKLGEITFFTATDGNHGRGVAWTANKLGQKSVVLMPKGSSEFRLNKIKG
                     EGADASITDLNYDDAVRLANDYAEADDHGVMVQDTAWDGYEEIPAWIMQGYGTMAKEA
                     IEQLKEYGVDRPTHVFVQAGVGSLAGAVQGYVASIYDECPITVVVEADEADCYYKSAE
                     AGDGKPRFVGGDMPTIMAGLACGEPNTIGFEVLKNYSSAFVSAPDWVSAKGMRILGNP
                     LRGDEKVISGESGAVTTGALVSILESEDLKDLREALKLDENSKVLLISTEGDTDPDKY
                     RDIVWNGECQSK"
     gene            26669..27856
                     /locus_tag="KR231_001409"
     CDS             26669..27856
                     /locus_tag="KR231_001409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YgeY family selenium metabolism-linked
                     hydrolase"
                     /protein_id="HBH0003792.1"
                     /translation="MLNETRKKQLTEVCQDLIRNASYSGQEENVVKAIEENFALLGFD
                     SWSRDRYGNIVGCIKGNKPGKKILFDGHIDTVPVPDASKWSVPPFEARIVDGKIYGRG
                     TSDMKGQVSAMMAAVSYFAEDTNKDFEGELYVAGVVHEEIFEGVSAREISKAVQPDYV
                     VIGESSELNLKIGQRGRGEIVVETFGKPAHSANPEKGINAVYKMANVIQKIQQLVPPT
                     HPVLGDGILVLTDIKSSPYPGASVVPDYCKATFDRRLLVGETREGVLAPIQALLDEMM
                     KEDPELNAKVSYAVEKADCYTGNTIESERFFPGWLYDEEDEFVQAAYKGLKEAGIDSE
                     ITQYSFCTNGSHYAGEAGIRTIGFGPSKENLAHTIDEYIELDQLFKGAEGYYGILKSV
                     YKK"
     gene            27872..29455
                     /locus_tag="KR231_001410"
     CDS             27872..29455
                     /locus_tag="KR231_001410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-aminoacylase"
                     /protein_id="HBH0003793.1"
                     /translation="MRTLIKHGLIVDGNKTPAYEGDILIENEKILKISQDLNEEADKV
                     IDAKGRVICPGFIDTHSHSDLVILVNPYNEVKIRQGITTEVLGQDGISMAPLPQEHIS
                     SWRKNLAGLDGESDEIDWKYETTENYLKMMDYNGVGLNETYLVPHGNVRMEAMGLEDR
                     PATKEEIQKMCEITERELKAGAIGLSTGLIYIPCAYSLTEEIIEMCKVVAKYDGVFVV
                     HQRSEADTILTSMEEIIEIGKQSGVKVHFSHFKVCGKANWKYIPQVIELLEKAEKEGI
                     RVSFDQYPYAAGSTMLGVVLPPWAHSGGTDKLIERLSDENERAKMKKDIANGIEGWDN
                     FIEFAGIDQIFVTSVKTEKNKDTIGKSLLEIGKMRGKDPLDATFDLLKEEENAVGMVD
                     FYGLEEHIIGFMKRDEQNVCTDGLLAGKPHPRAYGSFPKILGRYVRELNVLTIEEAVY
                     KMTKKAATSFSIKDRGELKEGYFADIVIFDKDTVSGCDDFINSMQYPTGIDYVIINGN
                     CVVEEGKYNKIKAGKVLKN"
     gene            29483..30811
                     /gene="ssnA"
                     /locus_tag="KR231_001411"
     CDS             29483..30811
                     /gene="ssnA"
                     /locus_tag="KR231_001411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898311.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative aminohydrolase SsnA"
                     /protein_id="HBH0003794.1"
                     /translation="MILVGNGRLISQDSLNPYMEDGCVVINDNLIEDIGTTEEMKAKY
                     PVHEFIDAGKKIIMPGLINSHMHIYSSFARGMAVPGKPSENFLEILNNLWWRLDKQLT
                     LEDTKYSAYATYIECIKNGVTTVYDHHASPNAIEGSLFTISDVAKDLGIRTCLCYEVS
                     DRDGGNTIQQGINENVNFIKYAQKDDTDMIKGMFGLHAAFTLSDDTLNKCASEMAGLD
                     TGYHVHVAEGLADLQYNVDKYGKRVLERFNDFGVLKEKTIAVHCIYISAEEISLLNKT
                     NTFVVHNPESNMGNAVGCSPAIELLKRGVTVGLGTDGYTSDMFESLKVANIIHKHHLK
                     DPRVGFEESQTMLFDNNRKIAKAYYKNDLGVLKKGAYADVIVVDYIPHTPLTENTIGG
                     HTIFGMSGRSVDTTIINGKVLMKDRKLINIDEESILAKSRELSQNLWNRI"
     gene            30956..32308
                     /locus_tag="KR231_001412"
     CDS             30956..32308
                     /locus_tag="KR231_001412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine permease"
                     /protein_id="HBH0003795.1"
                     /translation="MSRDKSPKIAPVDERLPVSKSWVFSLQHVLAMCAGAVAVPMMIG
                     SAARLDHASIVFLINACLFMAGIGTLIQSVGIGNIVGAKIPVIEGTSFAAVAGMTAIA
                     SSYSDSQVAIQTVFGSVIVAGLFCILLAPVFEKLIRFFPSVVTGTVVMVIGISLFPVG
                     IKWITDNKLEAVEPNSLALALAVLAITLLSFKFLKGIWNSTAILVGIVLGTLLSMAVG
                     MADFSAVNGVGWLNLNVPLKFGMPRFEPSAILSLCLIMLVLMTESVGNMIAIHEMVDK
                     EVTGKNIKRGLFGDGISTALSGIFNSFPITPFGQNTGIVGLTGIKSRFIAVYAGVILL
                     VLGFLPKFAAIIGAIPKPVLGGVGFAMFGMVMVGGVKTLSKVKFDGTKNGVIVAVSVG
                     LSMIPLTNPDFYHNFPTWVQTIFHSGITTGSLSAVLLNIFFNELGSKKEKNNKVEEAK
                     "
     gene            32500..33609
                     /locus_tag="KR231_001413"
     CDS             32500..33609
                     /locus_tag="KR231_001413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S binding protein"
                     /protein_id="HBH0003796.1"
                     /translation="MANLKVNLYGMEFLNPIMTAAGPGAKDGALCQEAAKGGAGAICT
                     KTISVLPADVPRPCMAKTNSGFLNTELWSELPKEQWIEEEYKKVKETGLPVIVSMGYS
                     AEQIAEVAPLVKPYADAVELSTHYVGTDVAPIVNALKAAKAVLDVPVFMKMSPHTDIQ
                     TIAKAVEEAGADGLVMINSFGPCMAIDVNTGYPIMGSKAGYGWLSGAPIRPLAIRCIY
                     EASQVVNIPIIGVGGITCGKDVAEMMMAGASAVQVCTEAILKGPSIYGKIAKELNEFL
                     DENGYADVNEIKGLTHKKMAARGFRTHSVAPVVDDNKCIKCKQCVTSCVYEALEVTDK
                     LNIDADKCFGCGLCVTRCPKGALSICYNQVEAMNE"
     gene            33892..35283
                     /gene="hydA"
                     /locus_tag="KR231_001414"
     CDS             33892..35283
                     /gene="hydA"
                     /locus_tag="KR231_001414"
                     /EC_number="3.5.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydropyrimidinase"
                     /protein_id="HBH0003797.1"
                     /translation="MGIVLKGGKVVTSEKTYCADVRIEDEKIVDIGLDISKENDEIVD
                     VSDSYVIPGGIDTHTHFDLDTGVTKTADNFETGTKAAIVGGTTTILDFATQAKGCSLK
                     DGLEEWHEKAKDKSYSDYGFHMAITDWNDSVCNEMEDMVKEGVSSFKLYMAYKGSLQV
                     DDGVIFEALRKAEEIGGIIGFHCENGDIICELVDKAKSENNLSPKYHQLTRPAIMEAE
                     ATSRLMKIAEVANSKVYVVHLSCKESLEEVLKAKQRGVDVIVETCPQYLLLNDELYDL
                     DGFESAKYVMSPPLRNKENNEILWNAILDNQIDTIGTDHCSFNYKGQKELGINDFSKI
                     PNGSPGVEHRMSLLYTYGVCKNKISINKMVEVTSTNAAKLFGMYPNKGTIEIGSDADI
                     LVLNPNKKSKIEAKKQLQNVDYTPYEGYEVDCQIEHVYLRGKEVVRDGELICNTPSGR
                     YINRRLTKGAREW"
     gene            35277..37838
                     /gene="xdh"
                     /locus_tag="KR231_001415"
     CDS             35277..37838
                     /gene="xdh"
                     /locus_tag="KR231_001415"
                     /EC_number="1.17.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="selenium-dependent xanthine dehydrogenase"
                     /protein_id="HBH0003798.1"
                     /translation="MVEFILNGEKVVAKEGKKLLDFLREDMNITSVKNGCSEGACGTC
                     MVIIDGKATKACVFKTDKLAGKNITTIEGLSERERDVFAYSFASQGAVQCGFCIPGMV
                     ISSKALIDVNNNPTEDDIKKALKGNICRCTGYVKIIKAVDLAAKIFRENIDVPKVNCK
                     GLVGENLPRVDAVGKALGYSEYVDDMRIEGMIYGSAVRAKYPRALVKKIDIEEAKAYP
                     GVVAVLTAKDIPGTIKVGHLKKDWDTLIPEGEITRYLGDGIVLVAAETREALEEAKKL
                     VKIDYEELTPLSTTEDALREDAPKIHETGNILVKEHLVRGNAKEKIENSKYVVTKRYT
                     TPATEHAFLEPECAVAGPYEEDGVIIYSTDQGVFATQHECADMLGLPYEKVRVINKMV
                     GGGFGGKEDMSVQHHAALLAYHTKRFVKVQLTRKESIIVHPKRHATEMEFTTACDENG
                     YLTGMKATIISDTGAYASLGGPVLQRLCTHAAGPYNYQDIDITGTAVYTNNPPGGAFR
                     GFGVTQSCFATECNLNLLAEMVGISPWEIRYKNAIRPGQVLPNGQFADEGTAMAETLE
                     AVKEEYEKHPRAGIACAMKNSGVGVGIPDVGRCRLVIKDGKVHIRTSASCIGQGLGTV
                     MTQVVCETASLLPENVVHEVPDTHLTPDSGNTTASRQTVFTGEATKVASNKLKEALDS
                     GKTLLDLEGEEFYGEYESITDKMGCDKENPVSHVAYGYATQVVILDENGKLEKVVAAH
                     DVGRAINPISLEGQIEGGVVMGLGYALTEDYPVVNSVPTAKFGTLGLFKSTDIPEIQA
                     LIVEKNKDLLAYGAKGVGEICTVPTAPAVQNAYYVFDKEFRTELPLQNTPYSKKK"
     gene            38014..39360
                     /gene="rpoN"
                     /locus_tag="KR231_001416"
     CDS             38014..39360
                     /gene="rpoN"
                     /locus_tag="KR231_001416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase factor sigma-54"
                     /protein_id="HBH0003799.1"
                     /translation="MNFNNSLELTQSQKLIMTTQLKQSLSILNMSKLELEEEIKREAE
                     NNPLVEVEKSGEINWEEYIKDMDRSRRLDRTEISYNPDNEVNLENLVKYSSNLYEDLK
                     FQISLYKLTDKELEVCEYIIDSLDEDGYLRTEEKVIVDTLKIDEELFEKCLISVQQLE
                     PSGVGARSLSECLMIQMASLGIYNEILEEIVTKDLNLIANNKYKEISKKYNMSLQKCV
                     ELINIIKTLDPKPGRTCSVEKSVYIQPDVTVEKIDDEFIVYLNEKDSYQIRINSYYKD
                     ILKNSQSDESAKEFIKERLNSATGLMKNIESRKTTVLKIAEEIVKAQDEFLRKGTKYI
                     KPLKMKDIAEKLEFHESTISRGVNGKYMLTPFGVYEFRYFFSSAIETENNEMASSTSI
                     KKIIKETIKDENKKKPLSDDHISKLLKEKGINVARRTVAKYREELGIPSSSKRKEY"
     gene            40156..41178
                     /locus_tag="KR231_001417"
     CDS             40156..41178
                     /locus_tag="KR231_001417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HBH0003800.1"
                     /translation="MKNLLEIQKKLIPQAIELMERRYSILRQISLSEPIGRRTLSNVL
                     EISERIIRSETEFLKEQGLIDVAVSGMTITKEGSDLLDKLKDIMSDIMGLSKLQDRVR
                     EKLGIKRVILVPGSCDENGSLLKDVTRYGCEYFLGILKDGDIVSITGGSTMLEFSNVI
                     KTDKRYPNSTIVPARGSMGTDVEMQSNNIVASISKKLHSNCKLLHIPDELDESAMKTL
                     SQVPEIKTTLEYIKRTDILVFSIGRADVMAKRRKLPEDKVDEILSKNAVGEAFGYYFN
                     KDGEIVYKLNTVGIDLETVKQVKETIAIFAGTEKVEALLAISNMHKNMVLVTDEESAY
                     KILSLL"
     gene            41238..42245
                     /gene="gap"
                     /locus_tag="KR231_001418"
     CDS             41238..42245
                     /gene="gap"
                     /locus_tag="KR231_001418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glyceraldehyde-3-phosphate dehydrogenase"
                     /protein_id="HBH0003801.1"
                     /translation="MVKVAINGFGRIGRLALRKMMEQQDKFEVVAINDLTDAKMLAHL
                     FKYDTAQGRFNGEIEVKEGAFVVNGKEIKVTAERNPADLPWAELGVDIVLECTGFFTS
                     KDKAEAHIQAGAKKVVISAPATGDLKTIVFNTNSDILDGSETVISGASCTTNCLAPMA
                     KVLNDKYGIEKGLMTTIHAYTNDQNTLDGPHPKGDLRRARAAAGNIVPNTTGAAKAIG
                     LVIPSLKGKLDGAAQRVPVVTGSITELVCTLGKNVTVEEINAAMKEASNESFGYTEEM
                     LVSSDIIGISYGSLFDATQTKVMEVDGKQLVKVVSWYDNEMSYTSQLIRTLGYFAQLA
                     K"
     gene            42467..43669
                     /locus_tag="KR231_001419"
     CDS             42467..43669
                     /locus_tag="KR231_001419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate kinase"
                     /protein_id="HBH0003802.1"
                     /translation="MSMLNKKTIEDIDVCGKKVLVRCDFNVPLQDGVITDENRLNGAL
                     PTIQYLISKGAKVILCSHLGKPKGEAKPELSLAPVAKRLSEMLGKEVVFAADDNVVGE
                     NAKKATEKMENGDVVLLENTRYRKEETKNEENFSKELASLAEIFVNDAFGTAHRAHCS
                     TVGAGEFLQERVCGYLIQKELKFLGEAVANPVRPFTAILGGAKVSDKLAVINELLEKV
                     DNLIIGGGMAYTFLKAQGYEVGTSLLEIDKVEYAKEMMEKAKNKGVNLLLPVDVVMAD
                     HFAPDATPIVTEDANVKEDYMGLDMGPKTIANFVKTIKESKTVVWNGPMGVFEFENFA
                     NGTLSVARAMAELTDATTVIGGGDSAAAVNQLGFGDKMTHVSTGGGASLEFLEGKELP
                     GIAALDNK"
     gene            43695..44438
                     /locus_tag="KR231_001420"
     CDS             43695..44438
                     /locus_tag="KR231_001420"
                     /EC_number="5.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="triose-phosphate isomerase"
                     /protein_id="HBH0003803.1"
                     /translation="MRKPIIAGNWKMHKTIKEALEFVNEVKDKVNSDKVEAVICAPFT
                     LLKDLKEATKGTNIKIGAQNMHFEEKGAFTGEVSPLMLKEIDMDYVVIGHSERRQYFN
                     ETDETVNKKVLKALEVGIDPILCVGETLEQREAGKTKDVCKVQVEKALENVLKDDLAK
                     VVVAYEPIWAIGTGKTATAEDANDVISYIREVIKGLYGELANEVRIQYGGSVKPSNVA
                     EIMGQSDIDGALVGGASLASNDYLDLVNF"
     gene            44447..45979
                     /locus_tag="KR231_001421"
     CDS             44447..45979
                     /locus_tag="KR231_001421"
                     /EC_number="5.4.2.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003228330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3-bisphosphoglycerate-independent
                     phosphoglycerate mutase"
                     /protein_id="HBH0003804.1"
                     /translation="MMKKPVALIIMDGFGYNKDVKGNAIAESKTPNLDRIKKEYPNTL
                     INASGLDVGLPDGQMGNSEVGHTNIGAGRIVYQDLTRITKSIKDGDFFTNKVLCEAMD
                     NAKENSLHVMGLLSDGGVHSHIDHLKAIIKMAKDKGVQKVYVHAFTDGRDTDPQSALE
                     YAKEVQASMDEIGVGEFATVSGRYYAMDRDKRWERVELAYNAMVRGIGEKANSIEEAI
                     QNSYDDGKNDEFIMPTVIMKDDKPVGSIKENDSIIFFNFRPDRARQITRALVCEEFDG
                     FKREDIKNFFVCLTEYDITIENVHIAFGPQSLANTLGEYLAKNGKTQLRAAETEKYAH
                     VTFFFNGGVEEPNKGEERLLIPSPKVATYDLKPEMSAYELTDKALDKLGEDKFDFIVL
                     NFANPDMVGHTGSIEAAIKAVETVDTCVGRLIDKIVELGGSAIITADHGNAEYMLDPE
                     TGKTVTAHSINPVPFIVVGQEYESAKLLDGGRLSDIAPTVLDMMKLEKPEEMTGHSLI
                     SK"
     gene            46567..47859
                     /gene="eno"
                     /locus_tag="KR231_001422"
     CDS             46567..47859
                     /gene="eno"
                     /locus_tag="KR231_001422"
                     /EC_number="4.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopyruvate hydratase"
                     /protein_id="HBH0003805.1"
                     /translation="MSVIELVYAREVLDSRGNPTVEVEVVLEDGAMGRAIVPSGASTG
                     AFEAVELRDGDKGRYLGKGVETAVANVNEIIAPEIEGMDAFDQPAIDAIMIELDGTPN
                     KGKLGANAILGVSMAVARAAADEIGLPLFQYLGGVNAKQLPVPMMNILNGGEHADNNV
                     DVQEFMILPVGACCFKEGLRMGAEVFHSLKKVLGEKGLACGVGDEGGFAPNLGSNREA
                     LELIVEAITKAGYKPGEDVMLGLDVAATEMYNKETKKYVLAGEGKELTAAEMVALYED
                     WSNNFPIITIEDGLDEEDWDGWKLLTEKLGNKLQLVGDDLFVTNTERLEKGIENGVAN
                     SILVKVNQIGTITETLDAIEMAKRAGYTAVISHRSGETEDSTIADLAVAVNAGQIKTG
                     APSRTDRVAKYNQLLRIEEMVGEQARYCGLKSFYNLKK"
     gene            48452..48676
                     /gene="secG"
                     /locus_tag="KR231_001423"
     CDS             48452..48676
                     /gene="secG"
                     /locus_tag="KR231_001423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecG"
                     /protein_id="HBH0003806.1"
                     /translation="MSNILMGVQVVLGILLVISIMPQDSKNALPSEFGGEGSQAYFKP
                     KGKQAFLARVTKITAVLFFINALALLIVKK"
     gene            complement(49060..49998)
                     /locus_tag="KR231_001424"
     CDS             complement(49060..49998)
                     /locus_tag="KR231_001424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AEC family transporter"
                     /protein_id="HBH0003807.1"
                     /translation="MENLILSINVVLPLFLTMSLGYVLKKLGLFDTHTLNKMNNVCFK
                     SFLPLLLFFNIYNTDLDGSLNFRLMAVAVIIIFSIFLILVFIIPKIEKDNKTRGALIQ
                     GVFRSNFVIFGIPVTISLFGDKSIGVTSLLIAVIVPMFNVLSVVILEIFRGGKVNIKH
                     MIKSVLTNPLIIASFIGLTMLILNINIPTFLHKTIGDISKIATPLSLIILGGSFSFSA
                     IKGHINPIILGVCGKLILVPAIFLPISIFLGFRNVELASLMIMLSAPTAVSSFTMAQQ
                     MDSDSELAGQIVVFTSGFSIITVFLIIFILKQNNLI"
     gene            complement(49986..>50379)
                     /locus_tag="KR231_001425"
     CDS             complement(49986..>50379)
                     /locus_tag="KR231_001425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HBH0003808.1"
                     /translation="KKIEHVVITNNNIENYINFYKKFGFSSKEMSKNYKLNARNIKIN
                     LNIKGYKFLPYVKNLQASRDNLCFKINTNIDEPKKYLEQNEIQIKRGIVECTGVFGNM
                     KSIYLKKTNGNLIELSNHRITESKPWKI"
BASE COUNT        19306 a         5934 c         8883 g        16256 t
ORIGIN      
        1 tgaagaggtg atgtgatgag attagatatg gatagtatgt tatatgtact aatttatatg
       61 acattattgg tatctatcat tggaagtata ttttattttt gtaaagacct cttaaatcat
      121 aaaattaagt atgttttaat aagagacata tttgtaaata gaattacata ttctgaagaa
      181 cgactgccta aacagtatat agtttttcag aaatatgata tttggaggta ttgtagtttg
      241 ttttaatttg aaatgaatct attataaatt ctaaagttta aaaataaaaa ggagagaata
      301 aaatggattt catttcaagt atattgcaag gattattaag tatattattt aattttacag
      361 gtgattttgg aatttctatt gtacttataa ctttaatagt taaattagta cttatgccac
      421 tatcattaaa acaaagattt tctgtaaaaa aacagcaaga attagctgaa aaaatggaat
      481 atataaaaga aaagtataag aatgatacta aagaattgga aaagcaaata caagtaagtt
      541 ctgtagaaag tatgaagagt atgctgggat gtcttatagt tttggttcaa atgccagtag
      601 tatatgcttt atatcatgta tgtttagata tgacaaagga atttacaaca attataattc
      661 catggattgc taatttaggt acatttgata atttgtttat attaccttgt atatatacat
      721 taattatgtt agcttcaaat ttagtgaatt atataccata tttaaaaata aattctcaag
      781 taaagtttaa caaacaaatg gctgtggtga ctaccataac aagtcttata ctaactgtta
      841 gaactccagt agccataggt ctgtacttta taacaagtgc aatttattca ttaattgaag
      901 atatttgctt tagaatatat tttaatcgaa aaaatagaat agtgacaaaa taatataatt
      961 attattagaa atattttagc ctgctaacat agaaaaagtt agtaggctat ttttatctat
     1021 gatatcaatt ccattaagaa tagtctaaaa aatactatca aaatgctata aaaaatacta
     1081 taaaaaaata gttgaaaaat aaataaatta atataaacta aaataaagcc tacaaaaaag
     1141 aggtgataaa tagaaatggc taaaatacta gttgtagaag atgaaaaaag aatgcaaaat
     1201 attattgtag aatatatgca aaagggagga tatacttgta taactgctga tgatggagtc
     1261 gaggcactta caatattaaa gagcaacaat atagatttaa tgatattgga tattatgatg
     1321 ccgtatttag atggattttc agtgtgtaga gtttcacgtg aaatgactaa tatacctatt
     1381 attatattga cagctaaagg tgaagaggag gataaattaa agggttatga atatggcgca
     1441 gatgattata taacaaaacc atttagccca aaagtacttt tagcaaaagt taatgctttg
     1501 ttacgtagat acactactga tattcccaaa aattcattga gtttaggaaa gatttttatt
     1561 atggtagcat caagacaagt gtatgtagaa gataaattga ttgatttaac atataaagaa
     1621 tttgaattat tgcgtttatt tatggaaaac cctaatcaag ttttttccag agagaaactt
     1681 ttaaattgta tatggggata tgattttgaa ggaaacacac gaactgtaga tacacatata
     1741 aaaaccttac gcaaaaagct tggtagtgaa ggacaccata tagttacatt aattcgttca
     1801 ggatataagt ttgaggttaa ggaatgaata gtttaagaaa gattatagaa aaactgaaaa
     1861 atgtagatat ttcaaattgg attaaacaaa attttggact atattcagtt agaaaaaaag
     1921 tgtttttact ttctaaatta tcaggagcgt taattatatt attttatctg gttgttgaag
     1981 aattttcgat aaactctaaa tttgaatttt ggatttggtt tataatactg gttatattta
     2041 ttatgagtat tgatttctta ttgggaaaat ttatttcaga accaatcaca tctataaata
     2101 aatctgcaaa aagtatgtcc caacttgatt tttctaatcc atgtactgta aatactaatg
     2161 atgaatttgg agaactttct aggagcctga atacaatgtc tacaaatcta caacaggcat
     2221 tatcagacct agaaagtgca aatattcaac ttgaaaagga tgtaaataag gaaagaatgc
     2281 tattggaaca aagaaaggag ttggtagata caatttcaca tgaaatgaag actccacttg
     2341 gcattatacg tgcgtataca gaggggctta tagatgaagt tgatgaagaa aaaaagaaaa
     2401 attatatgaa tgttataata gaagaaactg atagaatgaa caatatgatt gtatcattat
     2461 tagacttatc tgcattggaa gcaggagttt ctaaacttaa cccagagcgt tttgatttta
     2521 tagagtttgt tgaaactgtg gcaggtcgtc ttttaattga tataccagat gccaattttt
     2581 attttacata tgatttgcca gagtatgaag tttttgtagt ggcagataaa atgagaatgg
     2641 aacaagtagt agagaatcta gttattaatg caaagaagca tgttgtatat aatggtaatt
     2701 tagatttatc gattacatgt gaaaatggct tgcttttatt tgaaatttat aatgatggta
     2761 ggtttataga gcaagatgag atttcaaaga tttggtctaa gttttatcgt agtgttcaat
     2821 ctcagcgtac aggaggttca ggtctagggc ttgcaattgt ttcacaaata cttacaatgc
     2881 aagggttaga atatggagtg aataatcgtg atagaggagt agagttttat tttatgattc
     2941 caattgatga ataatttagt attaatttat aaattataag tatctgatgt aaaatatttt
     3001 tatttgtata cgtaagtatt taaagagaat aaaataaaaa aacttaatga aaaagcttaa
     3061 tgaaaaagtc taataaaaag cttaatgaaa agcttaataa aaagtcttgt tttcctgatg
     3121 aaaacaagat tttttattaa gctttttatt atttcacttc gatttcacaa gagagacact
     3181 ctgatttcac caaatagaaa taaaataggt taaataaatt aaaaaataga agcgtaatta
     3241 aataaggtta caagggggag tacttatgaa atggtataca tggttgacta ttatattgat
     3301 aatattgctt tctattccgc ttaaaattaa atttataaaa tggtgggata gacgacaaaa
     3361 aaatgataaa ggaggttatg atagatgata aaagtaagag agttaaaatt ttcttatgga
     3421 aaagataaac agatattgca tggacttaat tttgaagtaa aagaaggaga aatctttgga
     3481 ttccttggac ctaatggttc aggaaaatcc acaacacaga aaatcttaaa tggtgtttta
     3541 aaaggttaca atggtcacgt atccattttt ggtaaggaag ttaaagcata cacagaatct
     3601 ttatatcaaa agattggtgt tttatttgaa tttccttatt tatataccaa tttaagtgca
     3661 attgataatt tagaatattt ttcgtctttt tatcctaaaa atcaaaggag agacatatat
     3721 gaactcttag atttgttaga gtttaagaaa gagtttataa ataagcctgt atcatcctac
     3781 tcaaaaggta tgaagcaacg tattagcatg gcaagagcat tggtaagtaa tccaaagttg
     3841 ttatttttag atgagcctac tagtggactt gacccatctg gagctgtact atttcgtaag
     3901 attattgaag aagaacgaaa aaaaggaaca actatctttt tgactactca taatatgcta
     3961 gatgcagatt taatgtgtaa caatgtggct tttattgcag atggaaagat tatggtaata
     4021 gataaaccca aaaatttaaa aatgaaaaat agcaataata aagttgaagt ggaatttgta
     4081 tataatggaa atcgagatat tgaaattgta gatatacaag agttagaatc tggaataact
     4141 tttaaatatg atgaaatctt aagtgtacat tcaaaagaac ctacactaga agaagttttt
     4201 attaaataca caggaaggat gttagtgtaa tgtattctaa attttttacc ttagtaaaaa
     4261 aagatttttg gatgatgatt tatggtaaat tttttgtgct gacacttggc tctctcatac
     4321 tttattcgtg ttatattaat tttggttatg taaagtttat ggatgaagat agttatcaca
     4381 ataatgtata tctatataat ccagagaata taagcatgag tgcatctcca ttaattaatc
     4441 aagtttcttc tataggtgaa ttaaaagcaa aacttgatga agatacaagt gcagtttgta
     4501 ttgatatgag ttccagtaag ccgaaagtaa ttttacatga aagtattaaa ggagttgaca
     4561 attatagagc tgactatgca ttgtcattat tatcatcaga aaaagaccat aatagcaaaa
     4621 tatcagacaa caatgcaata attcaaatta atgataagga tacatctgag ataaaacaaa
     4681 gaaaagacat gacttgtgag attttattct ttgaaattgt agctattgga tttttaggga
     4741 ttgcctcttt attatttaaa gaaaagcaga tgggagtaat gcgtattact ggtattttac
     4801 ctgtaaaaag aagtcttttt atattatcaa agatatttgc tttttttata tgtgacctat
     4861 gttttacagt tcttttagta gtatttaata ttggattttt agaaggaata aaaatacttc
     4921 cacaagtatt agttcaagct agtattttat caattattat gtctttgatt ggaataggat
     4981 gctcaatgtt attgagagat tttaagcaat tttctcttat atatcttgtg gttgctgtat
     5041 tcataactac acctatattt ctatctgcaa atacatcttt tgaaatagat tggattaaat
     5101 atcatccctt ctatcatgtt tatagtcagc ttaaaaatgc gtttttcatg aatttttcaa
     5161 aagaattagt ttattttgta gtgtgttctt tgacaataat agttctattt ttacttgtaa
     5221 aatatatttt taataaagaa ttggttaggg agggataatc ttgataggat tacgttacca
     5281 gttaaagagt ataaaaaaag ataaaatgtg tataatttcc ttctttttac cagttgttat
     5341 ggcgatttta ataaatttta tgggaacaat tgatatatct tcattaggag agatacgttt
     5401 tggtatagtg aaggatacac ttcctgtaca aacagagcag tggttaaaga agtatggtat
     5461 ggtaagtgta tatgacacaa aaatgcattt aatacgtgaa attaaggata ttaaaacgga
     5521 cacaattgga gttgttagag atggtaaagg aataaaaact gtgttttatg gaaatgagat
     5581 taatgctata aaaaatgttg gaaagacatt gccagagatg tttagactaa agggtgattt
     5641 aaaagatgtt gaggttacaa tattgcctaa agatagtatt ttaaaagagt ttcaaaatgt
     5701 ttttattgct atgattttaa ttactgctat gtttatggga tgcaccttta atgcaatgaa
     5761 tattatatcg gaaaaagaag atggaatatc atttataaat gaagttttgc cacagagtag
     5821 aagtcagtat attatacaaa aagtattttt gggtctttta tgtgggtgtt tatcttcaat
     5881 gataactgta tttatatgtt tggatatttc aatattagat atgataatga tgttgttact
     5941 cgttgtattt tcagcattta tttcatcact tataggttta tttattggaa agttgtcaga
     6001 aggtcttatg gtaggaattg tttatattaa aatagtaatg attttattta taggtactcc
     6061 tttgttaata tatcttctag gggttaatac cagtggtata gggaatttat gctatataat
     6121 gccttcagtt gctacattta atggtattat ggagattatt aatggtaatg tcattattat
     6181 caaagatatt gtaattttgg ctgtacattg tgtagtatgg tttatgatat atattatttt
     6241 agataaaaaa agaaagttat cttttagtag ataactcagt ataattataa ttgggacaat
     6301 ttaataggtg atttaatata ctttgtatag tgtaatttat gtagtgcaat ttgtatactt
     6361 taatttatgt agtgtaatag ttagttttat tttataatta ttcaatataa tttagtaaga
     6421 agttcagtac aattagagct acttagtgga aaacttaata ggtacttaaa ctatataaat
     6481 actttatttt cctccatttg tactataaat ttaatttatg atataaatgg aggtattatt
     6541 atatgatttg ataaatttca tcattataac ctacaagtaa aggtattatt atataaagtt
     6601 aataaagata gtatcaaaat attatttgct ataaagagag ggactcaaaa taaagataaa
     6661 cctatttttc aatgttgaaa tgataaaata tatttgattt catataaaaa attttcttca
     6721 taaattaaaa agtccatttt aagccccttc atttttaacc agataaatcg agttaaacta
     6781 tttaaatata ttactcggat tcatttgact tagatattcc ttgcttgtaa aattgttttg
     6841 aataggggat agccaaagca aaaaataaaa gtataatccc tgctatgatt attaaattat
     6901 taatagaaat tacatctgcc attggtccga aaatcatcat accaagagga ataaaaccag
     6961 tatatataat aataggtaag ctaagaactc tacctagcat ttgtggtgct acatgctctt
     7021 gcaacatagt catagctgat gcttgaatga ttggaattga aaaattcgta aaaaacataa
     7081 atataaaaaa ttgccaagct tgtgttacaa gacctagaat aattgaaaaa atagcatagg
     7141 ataatattgc tagaaaaaag gtcttatttc tatttttaaa accaccaaaa actcctataa
     7201 tcaatccacc taaaaccata cctaaaaatc caatcatttc aataatagac aggtatatat
     7261 aacccttgcc aaatgttcgt tcaataagaa gtcctataag aaatcctgat ggaacacaaa
     7321 gaagcatgaa tgctccataa gtaaaaagca cttttctaat gaacttatct gaaaaacagt
     7381 actttatccc tgataccata tctgcaaaaa atgagacttt ttcagtttgt tttggtatat
     7441 catgtttagg aattttgatg aatattaata atacaatagc aataattgca gtaaatacat
     7501 caattaaaag aacttgattt attttattac caaatccaag tattgcagca gctacaatag
     7561 gaactataaa ttgtactata gactgtagac tactatttat accattaaaa cgcattaaat
     7621 gttcttctgg tacaagttga ggaatcattg cgtttacagc aggtgtttgt acaccacttc
     7681 ctagtgaacg tataacagat attactgata tggctattaa ttcacttgtt gtgccatttg
     7741 atgacatcat aaatagaatt agaactaatg tagatatagc aattgttgaa tctgatacaa
     7801 ttatgagtac ctttcgattg tagtagtctg cccatacacc agcaaaaaaa gaaattatca
     7861 tttgaggtat aaaggagcat acagttaaaa ctgttaccca tacacctgat gatgtctgaa
     7921 gtgtgacata ccatatcatt gccatttgta caagtgatga gccaaataag gaaatatatt
     7981 gacttgctaa aaaaagaatg acttttttct tccatgtaga attagtattt ttattttcca
     8041 tcctattcct cctttgattt gtgtgttgaa tttttcttgc tcttaaggat aacacacaaa
     8101 tcaaagtctg gagttagagt ggagggctag gaaaattgtt ttttcataat ttgaagatga
     8161 gatttcatgg tttttgcatt atgttcagct tctttcaatg aagttatcag tttgtcacac
     8221 actgagataa tttcgtcatc atcttttgga gtgtcaagga cagttttaat attagtatta
     8281 ggactagaag ataaagcatt taacattcgt aaaatagctg aaagagaata gtttgcacaa
     8341 cgaagtgcgc ttataatttt aagtcgtttt atatcttcat cagtatatac acgataacca
     8401 ttttgttttc tttttacttt taacaaacca ttcatttccc aatttcttaa agtatctatt
     8461 gtaacgttta agtgttctgc agtttctttt ctagttaaaa agagtttatt tgtttctgga
     8521 gtatttccat ttaaaatctg tgcaacaata gtaagtgctt cctcggcatt agatttttct
     8581 atttctaatt gttgcaagta ttgatttaca agactaatag ccttatcaaa gtccctattc
     8641 gctgatgttc ttacaatctc aagggcatct tttcttaatc ccctttgtac cacttcaatt
     8701 ttcaaggctg tacgagcaaa tctaaattgt tctatatgaa aatcattaaa gatacgataa
     8761 ccattggtat tacgcttagg tttaggtatt aagtttagtt cttcatataa acgtactgta
     8821 ttaggatgta caccaattaa atctgctacc tctgatgtcg tgtaagtgtc cattagtatt
     8881 caactccttt tagatatata gtattagtca taataacacc aaacaaaagt ctggtgttat
     8941 aatggagggt ttggctatct aagagtaatt agtttatgaa agagtaatta gtttatgaaa
     9001 gagtaattag tttatgaaag agtaattaat ctattataga agtaagtata tatttttcaa
     9061 tgaactccca tctatcacga ggtttaaaca ctattttaga tggtatggct attactaagt
     9121 catattgtgg aatacaacaa atagcatttc ctccagttcc cattgctgaa taccacaaaa
     9181 caccatcttt tttacatagc caccacagat aaccgtattc attactattc attttaactg
     9241 attcttcaat ccacgattta gatataatac gtttattatt ccaaatacca tcatttaaat
     9301 acagaaaacc aaatcgcaac atatctctag cactcaatgt aagtccccag ccacctatag
     9361 aataaccctg tctatctttt gcccaaccct taagattttt tccaaagaaa tcttcaaaac
     9421 caaaatcttt catatcataa tctggtataa ctttcatacc aataggttta aataagtact
     9481 cattagcaaa ttcacgagca gattttccag tagtttttgt tataatagct gaaagtaggt
     9541 gcgttccagc tgaagaatat ttgaaagtac caatttcgcc tttttgacca agttgattca
     9601 aggtatattt tatccaatct ttttgtttgc aaagtctttc taaagactca gtcatatttt
     9661 taaaagggta tggtgcagtc attgtaagta ggtgacgtat agttactgct tttttacata
     9721 tttcagaagg actacaagta tattcaggaa aaaaatcaac aaccttttgg tcaacatctt
     9781 ttatatatcc tttatctatt gcaataccta ttaaggctga tataatactt tttgtaactg
     9841 atgcaacatg aaaagtatca tcagcattat atccattata gtacttttca aagacaattt
     9901 ttccttttct tgcaataatt ataccattta tattgctata ttgtgagatt attaaaggtt
     9961 caagttgtga aagcttttct gaactcatac caacacttga agggtctact ttttcaaaaa
    10021 ttaagtctaa gcaattgttt ttattcatta aagatacctc cctgttatag attttggatt
    10081 ttcttttaga gtttttggag aaccttctgc aattatataa cctcctttgt caccaccttc
    10141 tggaccaagc tcaacaatcc agtcacaaac atttaataca tctatatcat gttcaacaac
    10201 aattacagaa tttccatttt caaccaattc atctaataat tgaatcaact tagaagtatc
    10261 atatagactt agaccagtag ttggctcatc caatacataa aggatattac catttcgttt
    10321 tttaccaatt tcttttgcaa gtttgattct ttgggattca ccaccactta aagtcggtgt
    10381 aggttggcct aattttatat accccatacc tatttgttct aatacattta agtgtgaaac
    10441 aatatttgga atatctttga agaaatgtac agattcagaa acactcatat ttaaaatatc
    10501 atgtatattt ttatttttat atttaataga taaagattca tcattaaatc tttttccctg
    10561 acattcactg catatatggt ctatacttag attatttccc aaccagacct tttcatatcc
    10621 actaccacta catttaggac aagccccttt ggagttaaat gagaaatgac cagctgtaaa
    10681 tccttgttct aacgattctg gctgacctgc aaatagtgta cgtatcttat cccatatacc
    10741 aatataagaa gcaggagttg agttcatatt tttgcctata ggagattgag atatctctga
    10801 atatccagaa atatgtttag taccaatcag tctatctgca atagtttcaa caactgcata
    10861 atcgtcttcc tcacctattt cactctctga agaatttatt tgattattga tagtatggtt
    10921 attaaattgg cttctaagaa gaggaagtag ggtgtctgat ataagtgaac tcttgccact
    10981 acctgatttt ccagatattc caaccatagc acccaaaggt aatgatacag ttacattttt
    11041 aagattattt gtatttgcat tttgaatagt tatacaaggt attttatcag tatgtgtaat
    11101 gtttttattg cttgttctat taggcattgg atattttcca gatagatact gtccagtaag
    11161 tgatttgtcg gattgaagta gaccttctaa atctccttga tatactaatt gaccaccttc
    11221 aacaccagct tttggaccaa tatcaataat atgttctgcc atttcaattg tgtttttatc
    11281 atgctcaact actatgaccg tattgcctaa atctttaagt ttctttagtg attttaagat
    11341 gtctattttt tctgattcat gcaatccagc tgttggttca tcaagcacat aaattaatga
    11401 gtccatctct gaatcgagat gtgaatttaa aaatagtctt tgcatttccc caccactcaa
    11461 agttgacatt tctcggtata aggatagatg acctaatcgt gattctatta aatgttgagt
    11521 tttggataaa atatcattta caagatttgt accaaatgtg tttaaattac cttgatttat
    11581 taagagttta aggaaatcat caatttctaa aatcgtcatt tttccaagtt ctccaatatg
    11641 ttttccgttt aaaagtactc tacgtgcttc ttcaccaatt ttaaaaccat tgcaatctga
    11701 acaggcagtc atagtataaa ctccatttaa atcttcgccc cttttgtaac gattgtgaaa
    11761 tacctttgat aaagaggaac tttttttacc attttcataa tgaccataga gtacttcatt
    11821 tcttatttct tcaggtagtt gtaagaattg tatgtctaaa taatcattga attttttaga
    11881 aaatactctc aaatatccag gtgtaatctt tgctctatct aagacttgtt ttagggtatc
    11941 atgcttatca aggactaatt tttcaatatt aatctcaaaa tatgcaccat gtccagagca
    12001 cttcatacac attccatctg aagagttgta tgagaaataa cttggtctta atcgttcttc
    12061 ctcatatcca caattattgc aaattagatt atcgcttaca ggagtatcac acatagtaca
    12121 cattatttga ccttccactg aatacaatag tgtaagcatg ttgagaatat tggttcttgt
    12181 gcctactgtt gaacgaggat tgctctggcg aataatattt tgttgaacag ctatagtggg
    12241 agctaaacct tgaatattat caaacttatc ttcactatca atacctgcaa gtatacctaa
    12301 agattgcaga tattgtttac gcccttcctc aaatacaatg tcaaacataa ggctagactt
    12361 acctgagcca ctgacacctg ttgcaacaac aagcttatct tttggaatag aaacatctat
    12421 atttttaaga ttgtgtatct ttgctccatt aatttttatt tctttcattg gttcacctca
    12481 ttttatcaat tttatcaaac cgtaaaatag ggatatatta atccttaata caagaataga
    12541 ttaggtgagg ttattaaaaa ggttctatag gtaaatatat atcgaccaag tgtctatttt
    12601 gagggtgatt gtgtgggttg ttaagatata cttcaaaagg gaaggaggca cgtagcttat
    12661 aattaccatt tgatagccat tcattataca taaaatccca cgcatcacta tattcagatt
    12721 ttgaaatatc aaaatgtccc acaagatatt ttccagaagg tattatcata ttgccaagat
    12781 tgtcattctc tttgacaaca atgttatctg gaatggtcat gcaaatacta gtccttaatt
    12841 gatgctcctg tgtaaattgt ggattatcat gataaatggc taatatttgt gtgttttcaa
    12901 gtccaagtag attctgctca cttgcatatg tgaataaccg ttctaaaagt tttgggaaag
    12961 tactggttag attaccatat gaaccagtat atctagtgta aatagtattc atattatcaa
    13021 gttctagaat ttcaatttca cctttaacct ctctagtatt cttacattta ggttttgata
    13081 tgcttctatt gtactgagaa attttatatg gttctttgca attcttgcta taattgtttc
    13141 tatattttat agggcttatt ttatagtaat ttttaaatgc tctcgagaaa actgctgaat
    13201 cagtaaagcc gaagtagtgt gcaatatcag taacagtcat gtcagttcta tgaataagaa
    13261 aagcagttgc attttctagt tttagcctat ttacatattg tgccaaagtt tctttttcta
    13321 ttgctttgaa gattctatga aaatgaaatt ttgaaaaacc tgctatatta gaaagttcat
    13381 caagagaaag aggttcatgt aaatgttctt ctatatagtc ttgcactttg caaatacgat
    13441 ttagatattc ttttttactt ttagcatttg tcatatatag ccctccttat tgtgtaaaat
    13501 gtgtatcaat taatttatag caatatagta ataaaatttt atgtttttgt aatttatgat
    13561 aaataagata gcgtttaatt ttttataatt gataaaagat ataagatgcc ttatatttgt
    13621 ctttgcatat aagtatagtc ttcgtaataa ttagtatacc atagtgattt atttttaatt
    13681 gtgtatttat ataaatacac aacttatgat atggacgaat tattatgcaa ataagctgta
    13741 attaaataaa ttgcaatata aaccagttga aacataagtt agggaaatat tatcaaagtt
    13801 attacttagc ataagagtat agatggaata aaataagatt aaaaaattac atactaaatt
    13861 taataaaatt tttatattaa aaataatatt aagtttattg tttaaataaa aaagttaaat
    13921 ctacactatt aacttattat acttaaaact ttaaaatgaa aatatcaaag aatacttttt
    13981 aataaaaata atcatttaat aagttattta aaaatctaaa aactttacaa caaattatat
    14041 atttaaattg gaggagtggg aatatgagta atagttttta tcaattaaat tcagcagtat
    14101 tatattttaa tgaaaaaaga gatgtaaata gaataaggtt taatcactat gtaatgagaa
    14161 aagaaaatat acaaagatta aaaggaactc tgccaagagg acaatttatg atgacagtaa
    14221 ggaaagctgc atctgacctt gatgtatcta tatctacaat aagtagactt gtaaatgaat
    14281 ttatagattt aggtatattg agattaataa gtaggggagt aaagggaaat tgttgttctg
    14341 tatatagtta tgtttgttct gaaagtagta atgcagaaat tgtaacaaag aatggtgata
    14401 ttttcaaaaa tatagagaaa tacattgatg caactattaa caataaccaa aaaacaatga
    14461 aatataaaca tagaaatgag ttgtttaaga acagtaatac caacatatac agccgtataa
    14521 atcaagagag tatagacaaa gattatgatt tgataattca tactgggtat gaaacagaaa
    14581 atgagacaaa gaaaaaagaa ttattaaaaa ataatttaaa taaaaagaat ttaaataaaa
    14641 atacctttga aaattcggat gaagatttga ctgaagattc tacttacaaa aatccagaaa
    14701 gcatacatga aattattata agaaaattaa atagtgaatc aggaaaaaat tttaaagctg
    14761 atttgagtat aactaaggca cttatagata aaagattaaa agaagggtat agtttagaag
    14821 atttttacaa ggttatagag gcaaaggtaa gaagatggag atatacagat atggaaatat
    14881 atatagaacc aacaattctg tttgggtatg aatttgagtc gtatttaaat gaggagagtt
    14941 ctttatctgc ttgtaattat ggtgatatgt gttatgaaga tatgtattga gatatttatt
    15001 aagatattag ttgcttttta gttgtttaaa atatgtttat gtataaatag tgtattaaaa
    15061 tggagttgtc tcaaaataga gagaagtctc ttcttaattg tttaaatgat gaaaatatat
    15121 ttgatttaat acaaaggaga gtgctttatg agttagaaga tttattttga gacactcact
    15181 ttttttaata tactggagaa atataaccca ttttacaaga gtgcatagat atatataatg
    15241 gcataatgtg gatttaaatt aaaaaaataa aataaagcca taaatattga aaatttcaat
    15301 atttatggct ttattgcttg taataattaa tagaatatat attttttatt aatcatctat
    15361 ttatattttt tattaatcat ctatttcaaa ttctaatatt ttaccagtaa ttgcattaat
    15421 tgttatctca tattcagttt ttccttttat tatttcacct tcatattctt tgtcatcttc
    15481 atcatactta aattttacta ttttcccacc aggcacttta tctagcatta ttgatttagc
    15541 tttttcagca ctaataatag aactgttgtc attagtatta gagttattct tatcattatc
    15601 atcaaagtca tcatcagaat cattgtccat gtcaatatct acaattcttc catcaaatgc
    15661 acttatctct aattcatatg ttttcttatt ttttattact ttagcctcat attcgttatc
    15721 ttcagcatca tatttacaat agattaaatt accattagga atagcatcta atgctataga
    15781 cttagcttta tccaatgata tattttgtgt acctaaatta ttatcattta agtcatcatc
    15841 tttttcaatt tctattattt taccagagta ggcatcaatt tctatctcat ataggatatt
    15901 atcctttata actttgcagt catattcatt atcatcttca tcataataac aaactaaaat
    15961 attgcttcct ggaagagctt gttttaatat ttctttagcc tgtattaaag atattttttt
    16021 agttttattt cttatgttca cattttttag ttttaaaata tcttcaaatg ctttttgatt
    16081 atatcctcct cctacttgtg ttatttcatc tatatcttta tttttaataa attctttttg
    16141 actatttaca aggctaccat tagatatcat tataggagaa ttttctttag cagctagtac
    16201 tcctattgat aatgaatcta ctaatgcatt ttcttggtta ataccatctt tagctacaaa
    16261 tacattattt atttttttat ctttataaaa tttatcaata atttttgcat tagtattgtt
    16321 tctatctgaa ccactgattc tttctctgtt tggatatttc tttactgtat tgtctgataa
    16381 aatcttattt cctccaacta tgtaagattt ttttatagac ctattgttta agaaatttat
    16441 actactatca ttgctgtttt catctgatac taatattata ggcatattat gtattgctgc
    16501 tggagaagct atactaactg catcagatag tccctttagt ccatttacaa ctgcaacatt
    16561 ttctatcttt tttatcttat ctatttcttt aagtacattt gtagacattt catatatatt
    16621 gtttcctact attttattta tttttatgtt aagtgatttt atttcatttt ctactttaga
    16681 agaaatgcta tttccactat ctacaatgta cacattatct acaccaagcc ttttaagctc
    16741 agccttagtt gaattttcaa tactgttgtt gtttactaaa agtataggtg cattctttag
    16801 cttagcaaat ggatttgcac aaagcgcact ttgaatagaa ttaccattaa ctataatggc
    16861 tgtttttgat tgaacccatc ccaatttact tacttctact gctgtttcat atcttgtttt
    16921 acctattaat ctttcttgct ttgtagtatt gtctgcaaaa attgctgaag aactagaaaa
    16981 aaacatcata cctgatatta atatagctaa atttttctta ttcatatttt tacctcacaa
    17041 tctttaaaaa tttgttattt agcatactta ataaaatata atcttaaaat caaattgata
    17101 ctgagtttga agttacaaaa tcaacaaata agatttcttt aatacaaaat tttccttttt
    17161 atatttaaca ttgtatcaca aatataaaaa ggaaaaaact ttttaaaaag ggtatacact
    17221 attcattttt tatcttataa ataagtcttt atcactgttt tatatatttt aaaatagaca
    17281 caagacctat ttctaaatct tttataaata ttttaggtga aatttctttt taaacatatc
    17341 taaaaagtat ttgtagtaat attaatggac tgaatttctt aaagtatata tttctttaca
    17401 tgttggagtt tgtgaagttt gagaattgga gggtgaaaga aacatgtaat ggattaatat
    17461 taaagaactg tatttttata atatttgtct taaaaataaa aaaatctatt gacttgaagt
    17521 taactccaag tagtaaagta taattataca agaattatat acttgtaaga atagttaaag
    17581 tagagagaaa aaacaaacaa gttttaaagg gggaagtaaa acaatggagg caaaaaaatt
    17641 aggatttgga ttaatgcgtt taccaataaa agatgaaaat gatgttacaa ctattgatat
    17701 ggaacattta aataaaatgg tagacacttt tttagaaagg ggatttacat attttgatac
    17761 ggcctatgtg tatcacatgg gaaaaagtga gatagcactt agagaatctc tagtaaaaag
    17821 acacaaaaga gagagtttta ctatagctac aaaacttcca ttaatggctt taaagaaaaa
    17881 agaagagcaa gaaaccattt ttaatgagca attagaaaaa tgtggtgtag actattttga
    17941 ctactatctt ttacacaata taggcgtgtc acattatgaa gtagctaaaa aatttgatag
    18001 ctttaagttt attgaagaaa agaaaaaaga aggaaaaata aagaatattg gtttttcttt
    18061 tcatgatagt gcagaattat tggataaagt cttgagtgag catccagaag tagacttcgt
    18121 gcaattacag attaattatt tagattggga taatgaaagc atacaatcta gaaaatgcta
    18181 cgaggtggca gagaagcata ataagcctgt aattgttatg gagccagtaa aaggaggtac
    18241 acttgcaaag ataccagaaa aagcagagaa attattgaat gactacaatc cagatatgtc
    18301 aatttcatct tgggcaatac gttttgcagc aagtaaagat aatgttatga tggtcttaag
    18361 tgggatgtca aatatggaac aattattaga caatacagga tatatgcaaa atttcaaacc
    18421 attcgtacaa gaggaatata atattataga tgaagcagta gagattatca acgaatcaat
    18481 tttaattcct tgtactgcct gtcagtattg tgtagaaggc tgtccaaaaa atatcgctat
    18541 tccaaactat tttgcgttgt acaatgcaga aaaacaagct cttaatactg gattttcaac
    18601 acagatggtc tactataata attatactaa aacttatgga aaggcctcag attgtattga
    18661 atgtaaacaa tgtgaagaaa gctgtcctca acacattaaa attatagatg ctttaaagaa
    18721 tgtagcagaa acctttgaga aataattcaa tctatacaat atcaagagga gaagatatgt
    18781 atgacgattt cagaagttag taaaaaatac gagctttcag cggatacttt acgatattat
    18841 gaacgaattg gtttaatacc acctgtaaat agaaataaaa gtggaattag gtcttttaca
    18901 gaagaagatt gtgagtgggt taatttcata aagtgtatga gaggtgcagg tctttctatt
    18961 gagacattaa ttgagtatgt agctatgttt caacaaggga gcagtactat caaagctaga
    19021 aaagaacttt taatagagca gagaaaccaa ctagcaaaaa gaatagaaga aatgcaaaaa
    19081 actttggaac gattaaattt taagattgat agatatgaag aaggtattat tgagaaagaa
    19141 aaagtattaa agagcagtag aaataagaaa atggaggcag tatcttatga gtaaaaatgt
    19201 attaatagta tcagctagtc ctagaaaagg tggaaattct gatttattgt gtgaccagtt
    19261 tatacaaggg gtattagaat ctaaaaatca agtggagaag atatttttaa aagataaaga
    19321 tattaactat tgtactggat gtggtgcttg ttatgaaaaa gaagcaaatt gttcacagac
    19381 agatgacatg ggagaaattc ttgaaaaaat gattggggca gatgtgattg ttttagcgac
    19441 tccagtttat ttttatacta tgaatgcgca aatgaaaact atgattgata gaacttgctc
    19501 tagatatact gaaatttgtg ataaagattt ctattttatc gttacagcag cagatgaaaa
    19561 tgtggctgat atggaaagaa caatagaagg atttagagga tttacatcat gtctaaatgg
    19621 ttctaaggaa aaaggtatag tatatggtgt aggtgcttgg aatgtaggtg atattaaggg
    19681 aagtaaggca atgaaacagg catatgaaat gggtaagttg gcgtagtatg tttgtataaa
    19741 attgtataaa attgaatata ttcttatcat ttcaacaata aaaagaggct tatctgtatt
    19801 ttgagacagc ctctttgtgc tatatcattt atttttattc tatatcctta ttataccctt
    19861 tattttttta tgcctattta agtatctgtt gttactcata tattttaata attaccctta
    19921 aaaaactata cagattcctg cataatatta ttttctttag taattaattt ttctaggttt
    19981 ttccaatcca tttcttccat atttgcaaaa taatgaccac ttcctatgca agtcaggtaa
    20041 gactttccat ctaattcaaa cgaagaacct ccaatacact ttgaattaca tttcttacaa
    20101 gtacgagttt tagttatact atctttaata gttttagagc attcctccac agcatcttta
    20161 tatgtattta gatgaaaaag atttgcttta actctccatt ttttttcatt acattcaata
    20221 gtaaataagc tacgttttgg tttcttagtt gaatatacta ttttgtaaga acgagcacct
    20281 gtttttggtt caattttaca atctaatgat ttaccaagtt catgtaaatg acatgcaata
    20341 tcataatctt taccacttag tacttctaac atttcttctg ttgtttctgc tgttaattca
    20401 cttttgctca tattaaaaaa atccccctat ataaataata atttcatatg aaaataatta
    20461 atataagtat attaaataaa actattaaaa tcaataaaat tactgcaatc ttacattatt
    20521 gggcatagaa tgagagctaa tgatttatta gaaataagac ttaatagtat gaaaatttac
    20581 ttagacgtgg tacaattcta taaaagattt aaaactagga aaggagaaag ttgttgagat
    20641 acggccaata taacaattta tttataagtt gtaaatttat tatgagatta attagattgt
    20701 taagtaatac tatcaaaagg tagttttttg gattttcagc aacagtggta gatattgata
    20761 attttttggt tattattata tttagctgtt atattttcaa taggctctat gataactagg
    20821 gtaaataagg tatgggtaaa ggttttatta tttataatag tgggattgtc aactatagtt
    20881 ctttcatatg taataacttg attatgcaaa attctatgaa gcaggaaccc tgtgacttta
    20941 gtcatgggag gttcagaatt taaggttaaa aaataacttt aatctgtaaa ttctcaaaac
    21001 aagaattctc atgttggtaa atttctagat atgagaaaaa aattgacatc ataaaaaagt
    21061 aattttagag cgttttttta cgaaaaaatt cagaagtaac tattttgaat gacttcacaa
    21121 aattttatat ataaataaag tttggcacgt taattgcttt aataaaagtt aacaagacac
    21181 aaataaacat aatcatctaa gtattgatta tttgaagttt tagatttgaa gtttaatcta
    21241 aaggttcgta ttaatattgg tgtttaggaa attttatttt cctgtaaata taacttaata
    21301 ataggaggtg aagtcatgtc aaaagtagta atagctacag agaaagctcc aggagcaatt
    21361 ggaccatatt ctcaagcaat tcaagttgga aacatagttt ctacatcagg tcaacttcca
    21421 atagatatga agactggcga gttagtatct gacccaaaag aagcaacaaa agcttcttta
    21481 gataatgtaa aagcaatatt agaacaagct ggtacaagta tggataaaat atttaagact
    21541 acagtattcg taaaagattt aaaggatttt aatgatatta atgaagtata tgctacatat
    21601 tttaaagaaa atccaccagc aaggtcatgt gtacaagttg ctcaattacc aaaagatgca
    21661 gttttagaaa ttgaagcaat ggcagtatta taagtattat aacaataaaa ccaataacaa
    21721 aactaataaa aattaaaaac taataaaaaa agtctacaat taaaaaagtt tatattaaaa
    21781 aagtctatat aaaaatctat ctaaatattt aactattgag cttttctcat ataatgtata
    21841 tttttatgtc aaaaatatat ttgttatatg aggaaagctt ttttttatta ttgtattgtg
    21901 atttatttta ttgtctgcat attataatta aggttactat ataaaacaaa ctttttataa
    21961 attaatattg tctgttttaa cgcaaatata taaataagta atgttttata tatattttaa
    22021 agagtgacta tatgttaaaa tatagctaaa ctgataattt ggtaaattaa attctaatgg
    22081 gggaaactat gttaagtaaa ttaaaagaat ttcaacaaga aatgataaaa tacactgaaa
    22141 cagtagctag tgtgttagat gtagatattg aaatagttga cgatagatta ataagaatta
    22201 gtggtacagg tctgtataaa tcaaagataa atgaaagcgt tgttactgag ggctttattt
    22261 atgacaatgt tatacagaca ggtcaggaat tagtcgtatt ggatatatgt gataatcagc
    22321 tttgtataga atgttcccat tacatgaaat gcctaaataa agtaataata gcagttccaa
    22381 taaagtataa taatcgaact ataggagtaa ttggtgctat tagcacagat aaaactaaaa
    22441 aagtagaaat aagtgcaaaa atagataatt atttaaaatt tgtcaatcat atatgcgatt
    22501 taatttctat gaaaatagaa gaacatgaag cgtcaaaaaa tagcagtaga aaaatggata
    22561 tgatgataga aatcattgaa aatgttgaaa aaggcgttat aatactagac ataaatagca
    22621 aaatatctta tataaacaat atagctctaa aaaaattaga tatagataaa aatataatag
    22681 aaaatatagt aaatatagta tctgttgaat cttcctcaaa tggacatgaa ttactagaaa
    22741 ttgatattga taacaaaatt tataatataa atgccaaaat aattccggta tatccatata
    22801 taaatcaata cgacaaaata ataatatttg acaagacata tatcaatcat aaaggacatg
    22861 gaaaagtgaa tagtggctgg ggaaatagtg atatagagtc tataattgga aattcagaag
    22921 caatgttaaa agtaaaagag agaactaaga aattagcaaa gtcaaattca actgtactta
    22981 taactgggga aagtggtacg ggtaaagagc taattgctag ggctatacat gctgaaggta
    23041 gcagatggaa caagccattt attgcgataa actgtgctgc tattccagaa aatctccttg
    23101 aaagtgagct atttggctat ataaaaggtg catttagtgg agctagtagt ggagggaaag
    23161 taggtaaatt tgaacttgca aatgaaggtg ttatatttct tgatgaaata ggagatttgt
    23221 caatgccttt acaagcaaag ttacttagag ttttacaaga gagaaaattt gcgagaattg
    23281 ggtcaaataa acttatagat ttagatataa gagtgattgc tgctacaaat aaaaacttat
    23341 tgaaattagt aaatgaaggt aagtttaggg atgatttata ctatagattg aatgtaattc
    23401 ctataaattt gccacctctt agggaaagaa aggatgatat tgaggcaata atgatgaagt
    23461 ttgcttctaa atattcttta gaattaggta ttcagttaaa taaaatagaa gaaaatgtaa
    23521 tgaatatgtt gattaactat aattggccgg gaaatataag ggaactggaa aatgcagttg
    23581 aatatatgat gaatttggtt ggagatgatg gaataatata taaagatatg cttccattag
    23641 atattttaaa ctattataat attaatggaa atatttataa aaataaggat gtaaatataa
    23701 tatttgaaga tgatatagtt ggagggatag tagagaatca agaaaggata ctttcaatta
    23761 aagaattaga gttgacttac ataaacaagt tgttgaataa gtatggaaga gatacaaaga
    23821 cgaagaagaa gatagcaaaa gacttaggca taggtttggc tacactatat agaaaattgg
    23881 aagaggaaca gtagtaatat aatattaaaa tgataggtat ttgtgtgttt ttatagatag
    23941 gtatttttac tttatggtgg aggtgttatt atgcaatatg cgatagagct atattatgat
    24001 aaaaaaacgg aaaagcaact ttttgattta tctaaaaaaa tcgctgatga aaaaattagt
    24061 acgaagtact tagaatggaa aacaagacct catcttactt tggcttgttt caatgatgtg
    24121 gatgaggctt gttgcataga caagctaaag gggtttgcac aaaaccataa ggtaatacct
    24181 gcttacattg gttcagtagg catgtttaat gatactaaaa cggtgtttgt atcacctata
    24241 atgaatagca atgtatcagt ttcagagaga attatatgag gtactacaag attttgattc
    24301 aaatggttgg gaatggtacc accccaatcg ttgggtaccc cattgcacaa tagcacttac
    24361 tggagatgat gaaagtgagg ctttttttcg ggcaagtgat gtattactgc gtgagttcaa
    24421 aaaaataagt ggtgagtttg tctcaatagg attggttaaa attacatttc ctgtggaaga
    24481 aatttttaca gtgaatatga ataggtaact ttaactctgt tgtggatgtt atgaatattt
    24541 tgtatagtgc atttcatcag ataaatgcga agttgcgaat ttcgacagct caatagtcgc
    24601 aagtagggca caatggtaca catattgcac ttttgcttat tggggggacg accatgtaaa
    24661 cttctgtaag aagctatgaa aagatttaag ccattttgga ggctttgggt aataaagaat
    24721 atttgggtaa taaagtatat aaatttatag agtttatgcg taagaaggtt atagccatat
    24781 atttatagaa aataaaagta gtaatatatc tgacaaaaca atagacatat aaaaaataag
    24841 agcataataa aggaagaatt aagataaata aacgatttct cgaattgata attctcgtat
    24901 tgataaaaat ttcccaatat gagaattttt tcttttataa atcttatttt tcacactcaa
    24961 aatttataaa ctttaaagaa attttataaa agtatgtaat tccaacataa aaaaattgtt
    25021 tttagaataa ataatattgg cacggtaatt gctttgctat aaggcacaaa gataaaaaat
    25081 taaaatgaca ccgaaaaatt tgaaagggga atataaaata aatgagagaa ataaaatgga
    25141 aattaaataa cttacctaaa tcagaggaaa aagaaaaagg aattgaattt ttaaaagatg
    25201 aagagattgc aaaggctaaa gcttttcatg aaagctttcc acaatatgaa aagactcctt
    25261 tagttaaatt agataactta gcaaaatcac taggcgtaag cggaatatat gttaaagacg
    25321 aatcttatag atttggctta aacgcattta aagttttagg tggttcttac tctatgggta
    25381 gatacttagc tcaaagatta aatacagata tatctgagtt agggtatgac aaattgactt
    25441 cgaaagaaat aaaagaaaaa ttaggagaaa taactttctt tacagctaca gatggaaatc
    25501 acggtagagg agttgcttgg acagctaata aattaggtca aaaatctgtt gtattaatgc
    25561 caaaaggttc ttctgaattt agattaaata aaatcaaagg agaaggtgca gatgctagta
    25621 taacagactt aaactatgat gatgcagtaa gattagctaa tgattatgca gaagctgatg
    25681 accatggagt aatggttcaa gatacagcat gggacggata tgaagaaata ccagcatgga
    25741 taatgcaagg atatggaact atggctaaag aagctataga acaattaaaa gaatatggag
    25801 tagatagacc aacacacgta tttgttcaag caggagttgg ttcacttgct ggtgcagttc
    25861 aagggtatgt tgcttcaata tatgatgaat gcccaataac agtagtagta gaggctgatg
    25921 aggctgattg ttactataaa tcagcagaag ctggagatgg aaaaccaaga tttgttggag
    25981 gagatatgcc aactataatg gcagggcttg cttgtggaga accaaacact ataggttttg
    26041 aagtgttaaa aaattattca tcagcattcg tttcagcacc agactgggta tctgctaaag
    26101 gtatgagaat attaggaaac cctctaagag gagatgagaa agtaatctct ggagaatctg
    26161 gagcagttac aactggagca ttagtttcaa tccttgaaag tgaagattta aaagacttaa
    26221 gagaagcttt gaaactagat gagaactcta aagtattatt aataagtaca gaaggagata
    26281 ctgaccctga taaatataga gatatagttt ggaatggtga atgccaaagt aaataaaaga
    26341 cttaaggaaa ataaaaactt aacaaataaa tgaaaaattt aaggaaaata aaaacttaaa
    26401 taagtgaaaa ctttaaataa aataaaaact aaaacaaatg aaaaatctaa ataaatgaaa
    26461 aagtaaagca aatgaaaaat tcaaaataaa aactaaataa aattaaataa aaccaaataa
    26521 aattaaaata aagtctaaat aaaaatttaa taaataaaat ataaagaaat aaaaaatcaa
    26581 tagattaagt gaaatgctaa taaattaaaa aagtgaaata tcaaaataaa acgtcaacaa
    26641 actaaaaatt atatggggga atatcaaaat gttaaatgaa acaagaaaaa aacaattaac
    26701 tgaagtatgc caagacttaa taagaaatgc tagttattca ggtcaagaag aaaacgtagt
    26761 aaaagctata gaagaaaatt ttgctttact aggttttgat agttggtcaa gagatagata
    26821 tggaaatata gtaggatgta taaaaggaaa taaaccaggt aaaaaaatat tatttgacgg
    26881 gcatatagat acagttccag ttccagatgc aagtaaatgg agtgttcctc cttttgaagc
    26941 gagaatagta gatgggaaaa tatatggtag aggaacttct gatatgaagg ggcaagtaag
    27001 tgctatgatg gctgctgttt catactttgc agaagatact aacaaagact ttgaaggtga
    27061 attgtatgta gcaggtgttg ttcatgaaga aatatttgaa ggtgtttcag ctagagagat
    27121 aagtaaggct gttcaacctg attatgttgt aataggtgaa tcttcagaat taaacttaaa
    27181 gataggtcaa agaggtagag gagaaatagt agtagaaact tttggtaaac cagctcactc
    27241 tgctaatcca gaaaaaggta taaatgcagt ttataaaatg gctaatgtaa tccaaaagat
    27301 acaacaatta gtacctccaa ctcatccagt tttaggtgat ggaatattag ttttaacaga
    27361 tataaaatct tctccatatc caggagcatc agtagtgcca gattattgca aagctacttt
    27421 tgatagaaga ttattagttg gagaaacaag agaaggcgta ttagctccaa tacaagcttt
    27481 attagatgaa atgatgaaag aagacccaga attaaatgca aaagtttctt atgcagttga
    27541 aaaagctgat tgctatacag gaaatactat agaaagtgaa agattcttcc caggttggtt
    27601 atatgatgaa gaagatgaat ttgttcaagc agcgtataag ggattaaaag aagctggaat
    27661 agattcagaa ataactcaat actcattctg tacgaatgga agtcactacg caggtgaggc
    27721 tggaataaga actataggat ttggtccttc taaggaaaat cttgctcata caatagatga
    27781 gtatatagaa ttagaccaat tattcaaagg tgcagaagga tattatggta tattaaaatc
    27841 agtttataaa aaataattag gagatggttt tgtgagaact ttaataaaac atgggcttat
    27901 agtagatgga aataaaacac cagcatatga aggagatatt ttaatagaaa acgagaaaat
    27961 attaaaaata tcacaagatt taaacgaaga agctgacaaa gttatagatg caaaaggtag
    28021 agttatatgt ccaggtttca tagatactca tagccattca gacctagtta ttttagttaa
    28081 tccatataat gaggtaaaga ttagacaggg aattacaaca gaagtgttgg gccaagatgg
    28141 tatatctatg gcccctctac ctcaagagca tatatcttct tggagaaaaa atttagcagg
    28201 tctagatggt gaaagtgatg aaattgattg gaaatatgaa acaacagaga attatttaaa
    28261 aatgatggat tacaatgggg taggtttaaa tgaaacttat ttagtacctc atggaaacgt
    28321 tagaatggaa gctatgggac ttgaagatag acctgctact aaagaagaaa ttcaaaaaat
    28381 gtgtgaaatc acagagagag aattaaaagc aggagctata ggattgtcta ctggacttat
    28441 atatatacct tgtgcatact cattgactga agaaattata gagatgtgta aggtagtagc
    28501 aaaatatgac ggagtatttg tagttcacca aagaagtgaa gcagatacaa ttttaacttc
    28561 aatggaagaa atcatagaaa ttggaaaaca atcaggagta aaagttcatt tttcacattt
    28621 taaggtttgt ggtaaagcaa actggaagta tataccacaa gttatagagc ttttagaaaa
    28681 agcagaaaag gaaggaataa gagtatcttt tgaccaatat ccatatgcag caggaagtac
    28741 aatgcttgga gtagttttac ctccttgggc acattctgga ggaactgata agttaataga
    28801 aagattaagt gatgaaaacg aaagagcaaa aatgaaaaaa gatatagcaa atggaataga
    28861 aggctgggat aattttatag aatttgctgg aatagaccaa atatttgtaa caagcgtaaa
    28921 aacagaaaag aataaagata caattggtaa gagcttatta gaaattggaa aaatgagagg
    28981 aaaagaccca ttagatgcaa cgtttgattt attaaaagaa gaagaaaatg cagttgggat
    29041 ggtagatttc tatggattag aagaacatat aataggattc atgaaaagag acgagcaaaa
    29101 tgtgtgtaca gatggtcttt tagcaggtaa accacatcca agagcttatg gttctttccc
    29161 taaaatacta ggaagatatg ttagagagtt gaatgtgtta acaatcgaag aagctgttta
    29221 taaaatgact aaaaaggcag ctacaagctt tagtataaaa gatagaggcg aattaaaaga
    29281 aggatatttt gcagatatag ttatatttga caaggataca gttagtggtt gtgatgattt
    29341 tatcaactct atgcagtacc ctacaggtat agattacgta attataaatg gaaattgtgt
    29401 tgttgaagaa ggaaaataca ataaaattaa agcaggaaaa gtacttaaaa attaaatctt
    29461 agctttaagg aggaataaat ttatgatttt agtggggaat gggaggctaa taagccaaga
    29521 ttctttaaat ccctatatgg aagatggatg tgtagtaata aatgataatc taattgaaga
    29581 tataggtact acagaagaaa tgaaagctaa atatccagta catgaattta tagatgcagg
    29641 caagaaaata atcatgccgg gtctaataaa ttcacatatg catatataca gctcatttgc
    29701 tagaggaatg gcagttccag gaaaaccttc tgagaacttt ttagagatac taaataattt
    29761 atggtggaga cttgacaaac agcttacact ggaagataca aaatacagtg catatgcaac
    29821 gtatatagaa tgtataaaaa atggtgtaac aacagtttat gaccatcatg caagtccaaa
    29881 tgcaattgaa ggcagtttgt ttacaatatc agatgttgca aaggatttgg gaattagaac
    29941 gtgtctttgt tatgaagtgt ctgatagaga tggtggaaat acaatccaac aaggtatcaa
    30001 tgaaaacgta aactttataa aatacgctca aaaagatgat acagacatga taaaaggaat
    30061 gtttgggctt catgctgcat ttacactatc tgatgataca ttaaataaat gtgcttcaga
    30121 gatggctggt cttgatacag gttaccatgt acatgttgct gaaggactag cagacttaca
    30181 atataatgta gataaatatg gaaaaagggt tttagaaaga ttcaatgatt ttggagtact
    30241 aaaagaaaaa acaatagcag ttcattgtat atatataagt gcagaagaaa tcagtctttt
    30301 aaataaaaca aatacatttg tagttcataa tccagaatct aatatgggaa atgcagttgg
    30361 atgttctcct gcaatagagt tattaaaaag gggagttaca gtaggattag gaactgatgg
    30421 atatactagc gatatgtttg aatcattaaa agttgccaat ataattcaca aacatcactt
    30481 aaaagaccca agagttggat ttgaagaatc acaaacaatg ttatttgata acaatagaaa
    30541 aatagctaaa gcttattata aaaatgacct aggagtactt aaaaaaggtg cttatgcaga
    30601 tgttatagta gttgattata taccacatac tccattgaca gaaaatacaa tagggggaca
    30661 cactattttt ggaatgagtg gaagaagcgt agatacaact attataaatg gaaaggtact
    30721 tatgaaagat agaaagttaa taaacataga tgaagaaagt attttagcaa aaagtagaga
    30781 attaagtcaa aatctatgga atagaattta aataattgat attaatatac aagtaagaaa
    30841 caagaattta gatgttaaaa acagagctta aacaaaaata ggaatttaaa tgaagtatat
    30901 aaataaaaaa tatacggaat agaatattaa attaaatata gaagggagac ccaaaatgtc
    30961 tcgagataaa agccctaaaa tagctccagt agatgaaagg ttacctgtat ccaaatcttg
    31021 ggtattttca ctacagcacg ttttagcaat gtgtgcagga gcagtagcag ttcctatgat
    31081 gataggaagt gctgcacgac tagatcatgc tagtattgtt tttttaataa atgcttgctt
    31141 gtttatggca ggtataggaa cactcataca aagtgttggt ataggaaata ttgtaggtgc
    31201 taaaatacca gtaatagaag gaactagttt tgccgctgtg gcaggtatga cagcaatagc
    31261 ctcatcatat agtgattcac aagttgcaat acagacagta tttggctctg taatagtagc
    31321 tggattgttt tgtatattac ttgctccagt atttgaaaaa ttaataagat ttttccctag
    31381 tgtggttact ggaacagttg ttatggtaat aggtatttca ctatttccag ttgggataaa
    31441 atggataact gacaacaaat tggaagcggt tgaaccaaac tcattagcat tagctttagc
    31501 agtattggca ataactttac tttcatttaa attcttaaaa ggaatttgga atagtacagc
    31561 tatattggta ggtatagtac ttggtacact actttccatg gcagttggaa tggcagattt
    31621 tagtgcagta aatggagttg gttggcttaa cttaaatgta cctttaaaat ttggaatgcc
    31681 tagatttgaa ccatctgcaa tactatcatt gtgtttgatt atgttggtac ttatgacgga
    31741 atcagttggt aatatgatag ctattcatga aatggtagac aaagaagtaa caggtaaaaa
    31801 tattaaaaga ggtctatttg gagatggaat atctacagca ttatctggaa tattcaattc
    31861 atttccaata actccatttg gtcaaaatac aggaatagta ggtcttacag gtataaaatc
    31921 aagatttata gcagtttacg caggggttat attgctagta cttggattct taccaaaatt
    31981 tgcagcaata ataggagcaa tacctaagcc tgttcttgga ggcgtaggat ttgcaatgtt
    32041 tggaatggta atggttggag gagtaaaaac tttaagcaaa gtgaaatttg atggaactaa
    32101 aaatggggtt atagtagcag ttagtgttgg tttgtctatg ataccactaa caaatcctga
    32161 tttctatcat aatttcccaa cttgggtaca aacaatattc catagtggaa taacaacagg
    32221 tagtttatca gcagtgcttt taaacatatt cttcaatgaa ctaggttcta aaaaagaaaa
    32281 aaataataaa gttgaagaag caaaataaaa ataaaacaag taaaaatcta tattgactta
    32341 aagtcattaa gcattaataa aaataattca gagatattaa taattcaaca aaactatctt
    32401 atattttaaa taatataaaa aagtaaataa ataacgaata caaataaaag aatacaatct
    32461 aaatattaaa aatatttaat ttaagggaga gataataata tggctaattt aaaagttaat
    32521 ttatatggaa tggaattttt aaacccaatt atgacagcgg caggacctgg agcaaaagat
    32581 ggtgctctct gtcaagaggc agcaaaaggt ggagcaggag ctatatgtac aaaaactata
    32641 tctgtattac cagctgatgt accaagacca tgtatggcaa aaactaatag tggtttttta
    32701 aacacagaat tatggtcaga gcttccaaaa gagcaatgga tagaggaaga atacaaaaag
    32761 gtaaaagaaa cagggcttcc agtaatagta agtatgggat attcagcaga gcaaatagct
    32821 gaggttgctc ctttagtaaa gccttatgca gatgcagttg aattatctac tcattatgta
    32881 ggtacagacg ttgcaccaat agtaaatgct ttaaaagctg caaaagctgt tttagatgta
    32941 ccagtattta tgaaaatgag tcctcatact gacattcaaa ctattgcaaa agctgttgaa
    33001 gaagcaggtg cagatggact tgtaatgata aactcatttg gaccatgtat ggcaatagat
    33061 gtaaatacag gataccctat aatgggaagt aaagctggat acggatggtt atcaggtgca
    33121 ccaataagac ctctagcaat aagatgtata tatgaagctt ctcaagttgt aaatatacca
    33181 ataatcggtg ttggtggaat cacttgtgga aaagacgtgg ctgaaatgat gatggctgga
    33241 gcaagtgctg ttcaagtatg tacagaagca atccttaaag ggccttctat ctatggaaaa
    33301 attgctaaag aattaaatga atttttagat gagaatggat atgctgatgt taatgaaata
    33361 aaaggattaa ctcataagaa aatggcagct agagggttta gaactcattc agtagctcca
    33421 gtagtggatg ataacaagtg tatcaaatgt aagcaatgtg taacaagctg tgtatacgaa
    33481 gctttagaag ttacagataa gttgaacata gatgcagaca agtgttttgg atgtggatta
    33541 tgtgtaacta gatgtccaaa aggagcttta agcatctgct acaatcaagt agaagctatg
    33601 aatgagtaat aattatatag aattttggta attaacttag agtaataggt attaggataa
    33661 taaaatatat cagataaaca aacacgcatt atgcattaat aatacagtct aaagttaata
    33721 attttattat attgatttaa ctaaatatta gtttagctga atattaattt aattaggtat
    33781 tggtttaatc ttaatataga tttactacgt ataagtgaac taactagatt actttaagtt
    33841 aattttttca tataaaataa attgatacat tacaagtaag gtggagtcta tatgggaatt
    33901 gttttaaaag gtgggaaagt agtaacaagt gaaaaaactt actgtgcaga tgtaagaata
    33961 gaagatgaaa aaatagtcga tataggtctt gatatatcaa aagaaaatga tgaaatagtt
    34021 gatgttagtg attcttatgt tataccagga ggtatagata cacacacaca ctttgactta
    34081 gatacaggcg ttactaagac agcagataac tttgagacag gaacaaaagc tgctatagta
    34141 ggaggaacta ctactatatt ggattttgct acacaagcta aaggatgttc tttgaaagac
    34201 ggattagaag aatggcatga aaaagctaag gataaatcat attcagatta tggctttcat
    34261 atggctataa cagattggaa tgactcggtt tgtaatgaaa tggaggatat ggtgaaagag
    34321 ggagtatctt catttaaact gtatatggcg tataaaggaa gccttcaagt tgatgatggt
    34381 gtaatctttg aagcattgag aaaagcagaa gagataggag ggattattgg tttccattgt
    34441 gaaaatgggg acataatatg tgaacttgtg gataaagcaa agtcagaaaa taatttatct
    34501 ccaaaatatc atcaattaac tagaccagct ataatggagg cagaagctac atcaagactt
    34561 atgaagatag ctgaagttgc aaactctaaa gtatatgtag ttcacttaag ctgtaaagaa
    34621 tccttagagg aggttttaaa agctaagcaa agaggtgtgg atgtaatagt tgaaacttgt
    34681 cctcaatacc ttctattaaa tgatgaatta tatgatttag atggatttga aagtgctaag
    34741 tatgtaatgt caccaccttt aagaaataaa gaaaataatg aaatattatg gaatgctatt
    34801 ttagataatc aaatagacac tataggaaca gaccattgtt cttttaatta taagggacag
    34861 aaggaacttg ggataaacga tttcagtaag ataccaaatg gttctccagg tgtagaacat
    34921 aggatgagtc ttttatacac atatggagtc tgtaaaaata aaatatctat caacaagatg
    34981 gtagaagtaa catcaactaa tgcagcaaag ttgtttggaa tgtatcctaa taaaggaact
    35041 atagaaatag gcagtgatgc agatatatta gtcttaaatc caaacaaaaa atccaaaata
    35101 gaagcaaaaa aacaattaca aaatgtagat tatacacctt atgaagggta tgaagtggat
    35161 tgtcaaatag aacatgttta tttaagagga aaagaagtag ttagagatgg agaattaatt
    35221 tgtaatactc caagtgggag atatataaat aggcgtctaa caaagggggc tagagaatgg
    35281 tagaatttat attaaatgga gagaaagttg ttgcaaaaga aggcaaaaaa cttttagact
    35341 tccttagaga agatatgaat ataacttcag ttaaaaatgg atgttcagaa ggtgcttgtg
    35401 gaacatgtat ggttataata gatggtaaag ctactaaagc atgtgtattt aaaactgata
    35461 aattagctgg gaaaaacata acaactatag agggattatc agagagagaa agagatgttt
    35521 ttgcatattc ttttgctagt caaggagctg tacaatgtgg attttgtatt ccaggtatgg
    35581 taattagttc aaaagcactt atagacgtta ataataatcc tactgaagat gatataaaga
    35641 aagctttaaa aggtaatata tgtagatgta cagggtatgt aaaaataatt aaagctgtcg
    35701 atttagcagc aaagattttt agagaaaata tagatgtgcc aaaagtaaac tgtaaaggtc
    35761 tagtaggtga aaatcttcct agagttgatg cagttggcaa agcacttgga tattctgaat
    35821 atgtagatga tatgagaatt gaaggtatga tttatggttc agcagttaga gctaagtatc
    35881 ctagagcttt agttaaaaaa atagatatag aagaagcaaa agcttatcca ggagttgttg
    35941 cagttctaac agctaaagat attccaggaa ctataaaggt agggcactta aagaaggatt
    36001 gggatacttt aataccagaa ggtgaaataa ctagatactt aggagatgga atagttttag
    36061 tagcagcaga aactagagaa gcgttagaag aggcaaaaaa gctagttaag atagattatg
    36121 aggaattaac accattaagt actacagaag atgcgcttag agaagatgct ccaaagatac
    36181 acgagacagg taatatactt gttaaggaac atttagtaag aggaaacgct aaagaaaaga
    36241 tagaaaattc aaaatatgtt gtaactaaaa gatatactac acctgctaca gaacacgcat
    36301 ttttagagcc tgaatgtgca gtagctggtc cttatgaaga ggatggagta ataatctatt
    36361 caacagacca aggggtgttt gccactcaac atgaatgtgc agatatgtta gggctaccat
    36421 atgagaaggt aagagttata aacaaaatgg taggaggagg atttggtgga aaagaagaca
    36481 tgagtgttca acaccatgca gccttacttg cataccatac taagagattt gtaaaagtac
    36541 agttaacaag aaaagaaagt attattgttc atccaaaacg acatgccaca gaaatggaat
    36601 ttacgacagc atgtgatgaa aatggatact taacaggtat gaaggcaacg ataatatctg
    36661 acacaggtgc atatgcctct cttggaggac cagtgctaca aagactgtgt actcatgcag
    36721 caggaccata taattatcaa gatattgata taacaggaac agcagtatat actaataacc
    36781 ctcctggagg agcatttaga ggatttggag ttacacagag ttgttttgca actgaatgta
    36841 atctaaattt acttgctgaa atggttggaa tatctccttg ggagataaga tataaaaatg
    36901 caataagacc tgggcaagtt ttaccaaatg gtcaatttgc agatgaagga acagcaatgg
    36961 cagagacact agaagctgta aaagaagagt atgaaaagca tccacgtgca ggtatagctt
    37021 gtgctatgaa aaatagtggg gttggagttg gtatacctga tgttggaaga tgtagattgg
    37081 tgataaaaga tggcaaagtc cacataagaa caagcgcttc ttgtataggt caagggcttg
    37141 gtactgttat gactcaagta gtttgtgaaa ctgctagcct acttcctgaa aatgtagtgc
    37201 atgaagttcc agatactcat ttaacaccag actctggtaa tactacggct tcaagacaga
    37261 cagtatttac gggagaagct actaaggttg cgtcaaataa gttaaaagaa gctttagact
    37321 ctggcaaaac tttacttgat ttagagggag aagagtttta tggagaatat gaaagtatta
    37381 cagataaaat gggttgtgac aaagaaaatc cagtaagtca tgttgcttat ggatatgcaa
    37441 cacaagttgt aattctggat gaaaatggaa aattggaaaa agtagtagca gcacatgatg
    37501 ttggaagagc tataaatcca atcagtttag agggtcaaat agaaggtgga gtagttatgg
    37561 gtcttggata tgctctaacc gaagattacc cagtagttaa ctctgttcct acagctaagt
    37621 ttggtacatt aggtttattt aaatctacag atataccaga aatacaagct ttaatagttg
    37681 aaaagaacaa agatttattg gcttatgggg caaaaggtgt aggagaaatt tgtacagttc
    37741 ctactgcacc agcagtacaa aatgcctatt atgtatttga taaagaattt agaactgaac
    37801 taccactaca aaatactcca tatagtaaaa aaaagtaaca aaaaaaagaa atattaaata
    37861 aaaaaataga tgaaattgta aataaaaaaa tagatgaaat tgtaaataaa aaaaaccctt
    37921 ttgcataagg tatattttaa atgatagaat atacatatac aggagggttt ttcttttata
    37981 aaataagttt aataaaattg agaggtgagc agaatgaatt ttaataatag tctagaatta
    38041 actcagtctc agaagctaat aatgactaca caacttaagc aatcattatc aatattaaat
    38101 atgagtaagt tagagttaga agaagagata aaaagagaag cagagaataa cccattagtt
    38161 gaagtcgaga aaagtgggga gataaattgg gaagagtata taaaagacat ggataggtca
    38221 agacgtttag atagaacaga gataagctat aatcctgata atgaagttaa tctagaaaat
    38281 ttagttaaat attcgtcaaa tttatatgaa gatttaaaat ttcagataag cctgtataaa
    38341 cttacagaca aagaattgga agtctgtgag tatataattg atagtttaga tgaggatgga
    38401 tatttaagaa ctgaggaaaa agtaattgtt gataccttaa agatagatga agaacttttt
    38461 gaaaaatgtt taattagtgt tcagcagttg gaacctagtg gagtaggggc aagaagtctt
    38521 tcagaatgtc tgatgataca aatggctagt ttaggaatat ataatgaaat tttagaggaa
    38581 atcgttacaa aagacttaaa tttaattgca aataataaat acaaagagat aagtaaaaag
    38641 tacaatatgt cattacaaaa atgtgttgaa ctaataaaca taattaagac attagaccca
    38701 aaaccaggaa gaacttgttc agtagagaaa agtgtataca ttcaacctga tgtaacagta
    38761 gaaaaaattg atgatgaatt tattgtatat ttaaatgaaa aagattctta tcaaataaga
    38821 atcaatagtt attataaaga catattaaaa aattcacagt ctgatgaaag tgcaaaagaa
    38881 tttataaaag aaagactaaa ttcagcaaca ggacttatga aaaatataga gagtaggaaa
    38941 actacagtac ttaagattgc agaagagata gtaaaagctc aagatgaatt tttgagaaaa
    39001 gggacaaaat atataaaacc tttgaaaatg aaagacatag cagaaaaatt agaatttcat
    39061 gaatctacta taagtagagg tgtaaatggt aaatatatgt taacaccttt tggtgtatat
    39121 gaatttagat actttttcag tagtgccatt gagactgaga ataatgaaat ggcatctagt
    39181 acaagcataa aaaaaattat aaaggaaaca ataaaagacg aaaataaaaa gaaaccttta
    39241 agtgatgacc atatatctaa gttactaaaa gaaaaaggaa tcaatgttgc aagaagaaca
    39301 gttgccaaat atcgtgaaga attaggaatc ccatcttcaa gtaagagaaa agaatactaa
    39361 taagtaaaag acaaatatca gtatggtaag gggaaaaggc taattaaaag atgaatgtag
    39421 attgggctaa aaattttatg aagtaaaata atagaatatg gaaaagtatt aaaatgctat
    39481 aagatattaa aaaactgggg aacattaaaa cattaagata gcaaagaaca taaaaaacta
    39541 aagaagatta aaacattaaa gaacattaga gctttgagga atattagaac tttaaagaat
    39601 attaaaattt ataaaatata aaaatactaa aaagaattga aaaactgggg aacattaaaa
    39661 tattgtaaaa tgctaaaaaa ctagaaaaca taattaaata agtgcttata aagaatgatt
    39721 aaattaaata agtgtttgta aagaataatt agatattaga aaaagaagaa tacctagata
    39781 aataaactat tattaaattt aataatcata aaaggaaaac acagggtata aataaaaatc
    39841 ttaactagat aaaagtaaac ttagttgtag ataaaaataa ctagaaataa aagtaactag
    39901 aaataaaatt atttatagta ataaatatta gaatgaaaat ataaaaaaat atatataaaa
    39961 agccttatat aaaaagaaaa aatactgtga tttgaaaatg gtggagaaat attttataaa
    40021 ataaaaaaat aaaaaagttt ttgaaaaact attgaaatct atacgcaaat cctataaaat
    40081 aaaaatatct tgtgggactt aaataaacac tagggacgaa aaaagtcccg aaaggaaagc
    40141 aataaggagt atgttatgaa gaacttatta gaaattcaaa agaaattgat tccacaggca
    40201 attgaactta tggaaagaag atactctatt ttaagacaaa tatctttaag tgaaccaata
    40261 ggtaggagaa cattatcaaa tgtattagag attagtgaaa gaataatcag gtcagaaact
    40321 gagtttttaa aagaacaagg acttatagac gtagctgtat ccgggatgac tatcactaaa
    40381 gaaggttctg atttgttaga taaacttaag gacatcatga gtgacatcat gggattgtct
    40441 aagttacaag atagagtcag agaaaagctt ggaataaaaa gggtaatatt agttcctgga
    40501 agctgtgatg aaaatggaag tttactaaaa gatgtaacta gatatggatg cgagtatttc
    40561 ttaggtattt taaaagatgg agatatcgtt tcaataacag gaggaagcac tatgttggag
    40621 ttttcaaacg ttattaaaac tgataagaga tacccaaact ctacaatagt tccagctaga
    40681 ggaagtatgg gaactgatgt agagatgcaa tctaataata tagttgcttc gataagtaag
    40741 aaattacatt ctaattgcaa acttttacat ataccagatg agttggatga aagtgcaatg
    40801 aaaactctta gccaagtgcc agagattaag acaactttgg agtatattaa aagaacagac
    40861 attttagttt ttagtatagg tagagcagat gtcatggcaa agagaagaaa acttccagaa
    40921 gacaaggttg atgagatatt atctaaaaat gcagttggag aagcatttgg atattatttc
    40981 aacaaagatg gagaaatagt ttacaaactg aacactgttg gaattgattt agaaacagtt
    41041 aaacaagtaa aagaaactat tgcaatcttt gcaggtactg aaaaagtaga agccttatta
    41101 gctatatcaa atatgcataa aaacatggtt cttgtaacag atgaagaaag tgcttataag
    41161 atattgtcat tattataaaa gtcaagacct agcacagagc tagaaaacat acatttactt
    41221 tataggaggt agcgaaaatg gttaaagtag ctataaatgg atttggaaga ataggaagat
    41281 tagcattaag aaaaatgatg gagcaacaag ataagttcga agttgttgca ataaacgact
    41341 taacagacgc taaaatgtta gctcatttat ttaaatatga tacagctcaa ggaagattta
    41401 acggagaaat agaagttaaa gaaggtgctt ttgtagtaaa cggaaaagaa ataaaagtaa
    41461 cagcagaaag aaatcctgct gacctaccat gggctgaatt aggagtagat atagtattag
    41521 aatgtacagg attctttaca tctaaagata aagctgaagc tcatatacaa gcaggggcta
    41581 agaaagttgt tatatctgca ccagctactg gagatttaaa aacaatagta ttcaacacaa
    41641 acagtgatat attagatggt tctgaaacag ttatatcagg agcttcttgt actactaact
    41701 gtttagctcc aatggctaaa gtattaaatg ataaatacgg tatagaaaaa ggattaatga
    41761 ctactataca tgcatacact aatgaccaaa atactttaga tggtcctcat ccaaaaggtg
    41821 atttaagaag agctagagct gctgctggaa acatagttcc aaacactaca ggagctgcaa
    41881 aagcaatagg cttagtaata ccttcattaa aaggaaaatt agatggggca gcacaaagag
    41941 taccagttgt aactggttca ataactgaat tagtttgtac attaggaaaa aatgttacag
    42001 ttgaagaaat aaatgcagct atgaaagaag cttcaaacga atctttcgga tatactgaag
    42061 aaatgttagt atcttctgac ataatcggaa taagctatgg ttcattattt gacgctactc
    42121 aaacaaaagt tatggaagta gatggaaaac aattagttaa agttgtttct tggtatgata
    42181 atgaaatgtc ttatacttct caattaataa gaactttagg atactttgca caattagcaa
    42241 aatagtcagt tttgagaaaa tagaaaagta gattgacaaa gtccgagttt gtagtttaat
    42301 actacggact caggactttt tttaagaaaa aatatataaa atacacctaa ataatgttac
    42361 atactatata taaaaatatg ataatatgat atatttaata gggtaaaagt atgtactata
    42421 ttatacttgg caataaaaaa ttactttatt aaaaggagag atatttatgt caatgcttaa
    42481 caaaaaaact atagaagata ttgatgtgtg cggaaaaaaa gtattagtaa gatgtgactt
    42541 taatgtgcca ttacaagatg gtgtaattac tgatgaaaat agattgaacg gagctttacc
    42601 aactattcaa tatttaattt ctaaaggtgc gaaagttata ttatgctctc acttaggaaa
    42661 gccaaaagga gaagctaagc cagaattatc tttagcacca gtagcaaaga gattatctga
    42721 gatgttagga aaagaagttg tatttgcagc agacgataat gttgtaggag aaaatgcaaa
    42781 gaaagcaact gaaaaaatgg aaaacggaga tgtagtatta ttagaaaata ctagatatag
    42841 aaaagaagaa actaaaaacg aagagaattt ctctaaagaa ttagcatcac ttgctgaaat
    42901 atttgtaaat gatgcgtttg gaactgctca tagagcacat tgctcaacag ttggtgcagg
    42961 tgagttctta caagagagag tttgtggata cttaattcaa aaagaattaa aattcttagg
    43021 agaagctgtt gcaaaccctg taagaccatt tacagctata cttggaggag ctaaagtttc
    43081 tgataaatta gctgttataa acgaattatt agaaaaagtt gataatctaa taataggtgg
    43141 aggaatggct tatacattct taaaagctca gggttatgaa gtaggaactt ctttacttga
    43201 aatagataaa gttgaatatg ctaaagaaat gatggaaaaa gctaagaata agggtgttaa
    43261 cttattatta ccagtagacg ttgttatggc agaccacttt gcaccagatg ctactccaat
    43321 agtaacagaa gatgctaatg taaaagaaga ttacatggga ctagatatgg gacctaagac
    43381 tatagcaaac tttgtaaaaa ctataaaaga atcaaaaact gtagtatgga atgggccaat
    43441 gggagtattt gaatttgaaa actttgcaaa tggtacatta tcagtagcta gagctatggc
    43501 agagttgact gatgcaacta ctgtaattgg cggtggagat agtgcagcag cagttaatca
    43561 attaggattt ggtgacaaga tgactcacgt atcaacaggt ggaggagcat cactagaatt
    43621 tttagaaggt aaagaattac caggtattgc agcattagat aataaataaa ctaatatata
    43681 gaggagattg taaaatgaga aaacctataa ttgcaggaaa ctggaaaatg cataaaacaa
    43741 taaaagaagc tttagaattt gtaaatgaag ttaaagataa agtaaattct gataaagtag
    43801 aagctgttat atgtgcacca tttactttat taaaggattt aaaagaagct actaagggta
    43861 caaatataaa gataggtgct caaaatatgc actttgaaga aaaaggagca tttacaggag
    43921 aagtttcacc tcttatgtta aaagaaatag atatggacta tgttgtaata ggacattcag
    43981 aaagaagaca atacttcaat gaaactgatg aaactgtaaa caagaaagtt ttaaaagcat
    44041 tagaagtagg aatagaccca atattatgtg ttggagaaac tttagaacaa agagaagctg
    44101 gaaaaactaa agatgtttgt aaagttcaag ttgaaaaagc tttagaaaat gttcttaaag
    44161 atgatttagc aaaagtagtt gttgcatatg agccaatctg ggctattgga actggtaaaa
    44221 ctgcaactgc tgaagatgct aatgacgtta tatcttatat aagagaagtt ataaaaggat
    44281 tatatggaga attagctaat gaagttagaa tacaatacgg tggaagtgtt aaaccttcaa
    44341 atgtagccga aataatgggt caaagtgata tagatggagc tttagtaggt ggagctagtt
    44401 tagctagtaa tgattaccta gaccttgtta atttctaagg agtgaaatga tgaaaaaacc
    44461 agttgcttta attattatgg acgggtttgg atacaataag gatgttaagg gaaatgcaat
    44521 tgctgagtcc aaaactccta atttagatag aataaaaaaa gagtatccaa acacattgat
    44581 aaatgctagt ggtcttgatg ttggtctacc tgatggtcaa atgggaaatt cagaagttgg
    44641 acacactaac ataggtgcag gtagaatagt atatcaagat ttaactagaa taacaaaatc
    44701 tataaaagat ggtgactttt ttactaataa agttttatgt gaagcaatgg ataatgcaaa
    44761 agaaaattct cttcatgtaa tgggactttt gtctgatgga ggagtacatt cacatataga
    44821 ccatcttaag gctataatca aaatggcaaa agataaaggc gtacaaaagg tgtatgttca
    44881 cgcatttact gatggtagag atactgaccc tcaaagtgca ttagaatatg ccaaagaagt
    44941 acaagctagt atggatgaaa ttggagtagg tgaatttgct acagtttctg gtagatacta
    45001 cgctatggat agagataaga gatgggaaag agtagaactt gcatacaatg ccatggttag
    45061 aggtattggt gaaaaagcaa attctattga ggaagctatt caaaactctt atgatgatgg
    45121 aaaaaatgat gagtttataa tgccaacagt tattatgaaa gatgataaac cagttggaag
    45181 tataaaggaa aatgattcaa ttatattctt caactttaga ccagatagag ctagacaaat
    45241 aactagagct ttagtttgtg aagagtttga tggatttaaa agagaagata ttaaaaactt
    45301 ctttgtatgc ttaacagagt acgatataac tatagagaat gtgcatatag catttggacc
    45361 tcaatcttta gccaacactc taggtgagta tctagctaaa aatggaaaaa ctcaacttag
    45421 agctgctgaa actgaaaagt atgcacatgt aactttcttc ttcaatggtg gagtagaaga
    45481 gccaaataaa ggtgaagaaa gactattgat accttctcca aaggttgcaa cttatgattt
    45541 aaaaccagaa atgtcagcat atgaattgac agataaagct ttagataaat taggagaaga
    45601 taagtttgac tttatagtat taaactttgc aaatcctgat atggtaggtc atacaggaag
    45661 tatagaagcg gctataaagg ctgttgaaac tgtagatact tgtgtaggaa gattgataga
    45721 taaaatagta gagttaggtg gaagtgcaat aataactgct gaccacggaa atgctgaata
    45781 tatgttagac ccagaaacag gaaaaactgt aacggctcac tctattaatc cagtaccatt
    45841 tattgtagtt ggtcaagaat atgaaagtgc aaaattattg gatggaggaa gattatctga
    45901 tatagcaccg actgttttag atatgatgaa gttagaaaag ccagaagaaa tgactggtca
    45961 ttcacttatt tcaaaatagt cgattctgat aagtagagaa taatatataa actacaatat
    46021 aaatttaaaa ataatgcagt ttaggtttat tttgtaaagt ttagacttta tgacagaaga
    46081 tttagatttt gtaagttttg gatattgtaa ggtgtagatg aagatatatt ttataaaatt
    46141 tacaagatag acaatttata aaataaaaaa ttataatata gataataatg taaataatga
    46201 tataaataat aacaagatag acaataacaa tataaataat aataattaat atatattata
    46261 taagcaaaaa ttttagaatc attagttgta cattttatgt ttaatgtttt aaatctagtt
    46321 ataatatttg tgtatttaag attggttttg gattttagac aagttttttt atattatata
    46381 aattaaaata ttataaaaaa taaaataaaa ataggaactt ttacaaattt acccatcaaa
    46441 taaatttgta cctaattttc aaaagcaact ttatgtacta taatatagaa agtagattaa
    46501 aatagtagac ggatgtttac agtaaatgaa aatttaacta atagaaaatc gaagggagat
    46561 atacaaatgt cagttattga attagtatat gctagagaag tattagactc aagaggaaat
    46621 ccaactgtag aagttgaagt agtattagaa gatggagcaa tgggaagagc aatagttcca
    46681 tcaggagcat ctacaggagc ttttgaagct gttgaattaa gagatggaga taagggaaga
    46741 tacttaggaa aaggtgtaga aacagctgtt gctaacgtaa atgaaataat agcacctgaa
    46801 atagaaggaa tggatgcatt tgaccaacca gctatagatg caatcatgat agaattagat
    46861 ggaactccaa acaaaggtaa attaggagct aatgctatat taggtgtttc aatggcagta
    46921 gctagagcag ctgctgatga aataggttta ccattattcc aatacctagg tggagtaaat
    46981 gctaaacaat tacctgttcc aatgatgaac atattaaacg gtggagagca tgctgataac
    47041 aacgttgatg ttcaagaatt tatgatatta ccagtaggag cttgttgttt caaagaaggt
    47101 ttaagaatgg gagcagaagt attccattcg ttaaagaaag ttttaggaga aaaaggatta
    47161 gcttgtggtg taggtgacga aggtggattt gctccaaact taggttcaaa cagagaagct
    47221 ttagaattaa tagttgaagc tataacaaaa gctggatata agccaggtga agacgttatg
    47281 ttaggtcttg acgttgctgc tacagaaatg tacaacaaag aaactaaaaa atacgtttta
    47341 gcaggagaag gaaaagagtt aactgctgct gaaatggttg ctttatatga agattggtca
    47401 aacaacttcc caataataac tatagaagat ggtttagacg aagaagattg ggatggatgg
    47461 aaattattaa ctgaaaaatt aggaaataaa ttacaattag ttggtgacga cttatttgtt
    47521 actaacacag agagattaga aaaaggaatt gaaaatggag tagctaactc tatattagtt
    47581 aaagttaatc aaataggtac aataactgaa actttagatg ctatagaaat ggctaagaga
    47641 gcaggatata ctgctgttat atctcacaga tcaggagaaa ctgaagattc tactatagca
    47701 gatttagctg ttgcagtaaa tgctggtcaa ataaaaactg gtgctccatc aagaactgat
    47761 agagttgcta agtacaacca attattaaga atagaagaaa tggttggaga gcaagctaga
    47821 tattgtggat taaaatcttt ctataactta aaaaaatagt tattaaaatg gttactaaaa
    47881 aagattaatg aagagagaat ataagatatt taagctcatc ttataagata taaaagagat
    47941 aagtgttaat tgatttttca attcacttat ccttttttat attttattac ttaattttat
    48001 tcatagattc agaaaaaata tgaataaatg tttctatctc atttttatct aattgcatag
    48061 gaggttttta ttaaaaaata aaagtgaaga catattttga tttaatcata attgtcatta
    48121 aagtattatt gctaaatgtg gattatttat tttaaattat gttgaaatta aaagttatat
    48181 caatatttta aaatgattgt tttattttgg tggctattta taatatatac aatgagagta
    48241 gattatttta agtgttaatt tatgcattaa tttaaatagt tttctcttct aagttttatt
    48301 catttttata ttgagaatat agtaatatat tatagtaaca atatattttt ttgtatgtta
    48361 tttatagcat aatagtcttg aaatggctat attattgtga tacactaaag agtaatgaaa
    48421 tttaagtaat aaacagatag gaggggcaag aatgagcaac attttaatgg gtgtgcaagt
    48481 agtactaggg attttactag taattagcat aatgcctcaa gattctaaga atgctttacc
    48541 ttcagaattt ggtggagaag gaagccaagc ttactttaaa ccaaaaggaa aacaagcatt
    48601 tcttgctaga gttacaaaga taacagcagt attatttttt ataaatgcat tggcattact
    48661 tatagttaag aagtagtgat attgttgaat aactggccat tatttaatta gtgcatttgc
    48721 tagacattta aaaattaaat ttagttttta ataaaagtac atcaacataa aaagtacgta
    48781 aaataaaagc tggactaatg attttatatg attagtccag tttttatttt atagattgac
    48841 tatttgttgg cgtttattat ttgtatttat atattgtttg tatttatata tttttttcaa
    48901 actaaaaaat atatagcaac actactttca ccatgtttaa tgagataata tacacaaagt
    48961 tatattatat agtaaaaata gtataataat atgtttttac gcaattaaat cgattttata
    49021 tatgtttctc ataataccaa tttgtgttat caaatatcat taaataagat tattctgctt
    49081 taaaataaat attattaaaa atactgtaat tatagaaaat ccagaagtaa atactacaat
    49141 ttgtccagct aattcactgt cagaatccat ctgttgtgcc attgtaaatg aagaaactgc
    49201 agttggagca gataacatta tcataagtga agctaattct acatttctaa atccaagaaa
    49261 aatgctaatt ggtaaaaata tagcaggtac aagtataagt tttccacata cgcccaatat
    49321 aatggggttt atatgcccct ttatagcaga aaaactaaaa gagccaccta gaattataag
    49381 tgataaagga gtagctattt tagaaatatc accaatagtt ttgtgtaaaa atgtaggtat
    49441 attaatattt aaaattagca ttgtcaatcc tataaaagag gcgattatga gtggatttgt
    49501 taagacgctt ttaatcatat gttttatatt tactttgcca cctctaaaaa tttcaagaat
    49561 tacaacagat aatacattaa acataggtac aataactgca attaataaag atgtgactcc
    49621 aatactctta tcgccaaata gtgaaattgt cacaggaata ccaaatataa cgaaattgct
    49681 acgaaataca ccttgtatta atgcacccct tgtcttatta tctttttcaa ttttaggaat
    49741 aataaagact aagattaaga agattgaaaa aataattata acagctacag ccataagcct
    49801 aaaattaaga gaaccatcta aatctgtatt gtatatatta aaaaataata ataatggcaa
    49861 gaaagacttg aagcagacat tattcatttt atttaaagta tgagtatcaa atagacctaa
    49921 tttttttaga acatatccaa gtgacattgt gagaaacaaa ggaagaacaa catttattga
    49981 taggattaaa ttttccaagg tttactctcc gtgattctat gatttgataa ttcaattaaa
    50041 tttccattag tttttttcaa ataaatagat ttcatattac caaagacacc tgtacattct
    50101 acaattcctc gcttaatttg aatctcattt tgttctaagt atttttttgg ctcatcaata
    50161 tttgtgttta ttttaaaaca taagttatct ctacttgctt gtaaattttt aacataaggt
    50221 aaaaatttat aaccttttat gttaagattt atcttaatat ttctagcatt aagtttataa
    50281 tttttgctca tttctttaga tgaaaaacca aattttttat aaaaattgat ataattttct
    50341 atattattat tagtaatgac cacatgttct atttttttt
//
LOCUS       DAEPHU010000023        48792 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 01A10CD0081
            SAMN05941466-rid12468953.denovo.023, whole genome shotgun sequence.
ACCESSION   DAEPHU010000023 DAEPHU010000000
VERSION     DAEPHU010000023.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941466
            Sequence Read Archive: SRR6291087
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 48792)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 48792)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068158.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 22:43:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,892
            CDSs (total)                      :: 3,805
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 87
            rRNAs                             :: 8, 1, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 55
            CDSs (without protein)            :: 55
            Pseudo Genes (ambiguous residues) :: 0 of 55
            Pseudo Genes (frameshifted)       :: 21 of 55
            Pseudo Genes (incomplete)         :: 28 of 55
            Pseudo Genes (internal stop)      :: 16 of 55
            Pseudo Genes (multiple problems)  :: 8 of 55
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..48792
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941466-rid12468953.denovo.023"
                     /strain="01A10CD0081"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            complement(103..1548)
                     /locus_tag="KR231_001426"
     CDS             complement(103..1548)
                     /locus_tag="KR231_001426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HBH0003809.1"
                     /translation="MIKLGKFPKGFLWGGAVAANQLEGAWNEGGKGWCLADVHMYDKD
                     RDISKPYESDMTIERIKFAMKDNNGYYPKRSGIDFYHTYKEDLKLLKELGLKCFRFSI
                     NWARIFPNGDDLEPNEEGLKFYDNLINEVIDNGMEPIVTLLHYETPLNLVLKYKGWSN
                     RKVVDFFVRYAELILNRYKNKVKYWIVINQINLIHYESFNSVAFCVDQVDNVEETRYQ
                     AIHHQFIATALTKKLGKEINSDMMIGMMMADCTSYPEDCDPENVVFALKRNRLQYFFT
                     DVSFRGEYPVYIKRFFKENNINIVMEEGDDKILKENTMDFLALSYYYSTTVSASKNTM
                     NPTDNIKNPYLKANPWGWAIDPKGLYNTLSQYYDRYQKPIMIAENGFGMHDKFEDGKV
                     HDSYRIDYLGKHIEQIGEAIADGTEILAYCMWSPIDIVSCSSQEMEKRYGFIYVDIDN
                     NGNGSKKRYKKDSFYWYQNVIRTNGEELKEK"
     gene            complement(1570..1923)
                     /locus_tag="KR231_001427"
     CDS             complement(1570..1923)
                     /locus_tag="KR231_001427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HBH0003810.1"
                     /translation="MTIEEHIIDEELVEVAMQIILRAGEARTEIKHALNDLEKFDYRN
                     ADLKLAKAKGFMTEAHRAQTKIIQGEAGGEKRAHSLLFAHAQDTLMTIFSELNITMSL
                     VGIVKSIEYKVNNSK"
     gene            complement(1952..3199)
                     /locus_tag="KR231_001428"
     CDS             complement(1952..3199)
                     /locus_tag="KR231_001428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBH0003811.1"
                     /translation="MGRVFMNKFIDFLSEKFTPVVNNMTKNIWVQSVQSTIMKVLPMV
                     FVGSLVTIVSVLKNYISFLPDLSPINQYTFGLLGLFIAFLLPMEIMKNKKFESMSVVA
                     GLAGAGLMLMMIRPEITNEGAIFNFNRFGGEGMLVSLVAGLFSGLIMSLFGSFSFFGE
                     DSALPDFVSKWFDNMLPITVIMFVGWGLIYGLNFDMFEIIVRVFKPVSDIAQTLPGFV
                     LLNFLVVFIYSLGISGWVLSPITYSIQLGAIAANAAAVASGGVATNIYVYEVIQTGWI
                     TLGGLGATLPLVIMMCLSRVGRIKAIGRACIVPSIMNINEPVIFGAPVAWNPFLMLPM
                     WIGTVVISITTYLSMSMGFVTIPSKVFNLWYVPFGISTFTVNQDVRGLIVLAINIVLL
                     FMIWYPFFKAYEKEEIKLESQEV"
     gene            complement(3207..3524)
                     /locus_tag="KR231_001429"
     CDS             complement(3207..3524)
                     /locus_tag="KR231_001429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBH0003812.1"
                     /translation="MKNIRVLLACGSGASTGFMATSMRKSAKKKGIEADIKARSESEI
                     DKYLSEIDCLLLGPHLDYMKEEIQQKANEYNVPVACISKTAYGRLDGAKALEEALELI
                     SNK"
     gene            3766..5679
                     /locus_tag="KR231_001430"
     CDS             3766..5679
                     /locus_tag="KR231_001430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBH0003813.1"
                     /translation="MKTSKKELFLNFIKTQHDWIDSSTLANYLNVSTRSIRKYVNEIN
                     SNGEFILSSKKGYKVNLNNNCQTKVDSSENISPDNRLNLILKELIVNSNGINIFDLSE
                     DLFVSPATIEGDIVKANKFIGSYNLKIKQSKFLLKLIGNESAKRKLMSSIIFKETGSD
                     FLSLFDVQKIYQEYNLTKLKENIIYILKKYNLFINEYAINNILLHLMITIDRIKKNNY
                     IESVEVVNYIDNNNDISISRDISNFLESEYNITLTSAELYYLVFQLTNKTTVLNYHEM
                     DTKSLPNYIDEHFVKLTKKIIKNVYDLYFIDLSDDEFVVKFTLHVKNLISRAKNNQVL
                     RNQIPQKLKDSYPLIYDISVYICNQIQILENIEIDEDEISYISLHVGSFFDRQKLLED
                     KILCALITPNYYDLQFKIVRDLEKRFNESIEIIQIFSDTHNLDFDNKVDMVITTLPIS
                     DRCPIPFVYVNPYLNRKDYDNIQSKFIQIKDRKNILTVQNHLEMYFSESLFMKNIYLD
                     SAKDYIRFMGNILYENKYVKPNYIDDVLIREKMSSTAFNNNVAIPHSMKMDALKTGVC
                     LIVNDKPVKWGEEKVQIIAMIPINEKEKEKFNYIFESFIEILSEWNNVKELTKADNYS
                     SFMNRIAYLIQNI"
     gene            complement(5802..6956)
                     /locus_tag="KR231_001431"
     CDS             complement(5802..6956)
                     /locus_tag="KR231_001431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate kinase"
                     /protein_id="HBH0003814.1"
                     /translation="MKILISIDSLKGSLSSIEAGNAIKKGILKVKEDAQVKILPLADG
                     GEGTVDALVQGMNGKKDTIEVTGPIAKKVDATYGLLKNTSTAIIEIAQASGLTLVPTE
                     LRNPLYTTTYGVGEIIKEAINKGYRNFIVGIGGSATNDAGIGMLQALGFEFYDENNKL
                     VGLGGKVLNEIRHIKIENRLKELDECKFKIACDVNNPLFGKNGAAYIYGSQKGATSEI
                     IEELDNGLRNFSKVVKNYLSKDVANVEGAGAAGGLGFAFLAFLNSKLESGIKIILEEI
                     KLEEELKDADFVITGEGRLDNQTAMGKAPIGVAKLAKKYGVKVIGLAGATTEDAVKCN
                     EEGIDAYFSIVNRAMTIEEAMDKATASENMTATTTQIFNLITSIQQSKNM"
     gene            complement(7216..9831)
                     /gene="mngB"
                     /locus_tag="KR231_001432"
     CDS             complement(7216..9831)
                     /gene="mngB"
                     /locus_tag="KR231_001432"
                     /EC_number="3.2.1.170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannosylglycerate hydrolase"
                     /protein_id="HBH0003815.1"
                     /translation="MKKNVHIVPHMHWDREWYFSTEESRILLVNNMEEIMDMLENNHN
                     YPYYVMDGQTAILEDYLAVKPECKERIKKLVQEGRLIIGPWYTQTDEMVVGGESILRN
                     LLYGIKDCDEFGEYMKIGYLPDSFGQSAQMPQILNGFDIKYSMFWRGCSERKGTNKTE
                     FNWKSDDGSSVLVQILPLGYAIGKYLPMNEDELRTRMDKYLPVLDKGATTDHIILPNG
                     HDQMPIQKNIFEVIYKLKECYPERKFFLSRYENIFKELEKNEDIDTIKGEFLDGKYMR
                     VHRSIFSTRMDIKSANARIESKITNILEPLASIAYSLGFEYHHGLIELIWKEIMKNHA
                     HDSIGCCCSDKVHHEIMNRFFLAEEKVDQLITFYKRRIVDAMSCEMALDKLVAFNLMP
                     YDRNEIVSAQVITKMKAFEIFDKDNNKLDFEVVHKEVIDAGLIDRQIVHYGNYDSFMV
                     YTINFKDKIPAMGYKAYMIKEVEHMLEKAYEVCDMVDNDFYTIQVNENGTLKIFDKKL
                     NKTFENVLLMENGGDEGDEYDFSPLPNEKLIFNDNIVANSTIKKNRFNNEIKINYRLK
                     VPKDIQARKNNRADSFIDFDIVINVPNDKAIIDVVFNINNQARDCRVRTYIPTNIASK
                     FSVSDNQFGHIKRSVYDDAMEVWQQEEWSERPDSIYPMLTFVGLSDKEHGVAVLTNST
                     REFEIVGEKFDTIAITLFRSVGFLGKEEMARRPGRPSGIKLPTPDSQMIGDIKIDLAI
                     VTHEKSTLEANVANMAKEYLTKIQTYNKMPYNAMKLNQSEIEVDYSYSLLKETNKDLV
                     LSVVKKAEKQEALVVRFYNSKEETKSANIVFNKNIKTAKWINLNEKELESISIDNNSV
                     NVECLMNQVKTILVK"
     gene            complement(9975..11900)
                     /gene="mngA"
                     /locus_tag="KR231_001433"
     CDS             complement(9975..11900)
                     /gene="mngA"
                     /locus_tag="KR231_001433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS 2-O-a-mannosyl-D-glycerate transporter
                     subunit IIABC"
                     /protein_id="HBH0003816.1"
                     /translation="MEFKKITNENLVFLKQKIKTKKDAIKFLARKLYDEGKLTSYEEY
                     LEAVMYRETLSPTGFERGLAIPHGKSKSVKEAAFAAMTLETPIENWESVDPNNKVEII
                     FLIAVPENEGGNTHIQILSELVTRLSNEDYMNMLLNSKTKKELFNNLDIKEKKEQIKE
                     EIRIQNESKKIILAITACPAGIAHTYMSAEALIKAGKEIGVDVYVEKQGANGMVDPHT
                     PDIIKRADAIIYATDVAPKNTERFEHLPNIKTSVAAPLKRAKEIIYEALEVAQKQGKG
                     DYIEKSSDISYCEKSSWKKDVKSAILTGVSHIIPLIVAGGMILAFAVLASQAFGLQEL
                     YNQEGSWLWQLRKLSGGMLGTLMVPVLSAYMSYSLAEKPGLGPGFAAGLAADLIGSGF
                     LGGMLGGLLAGYIVKFLKKNIPAKGTLAGFVSFWVYPVVGSLVVGLLMLFVVGKPVAA
                     LNNGLINWLNGMTGVNAILLGAIIGAMVSFDLGGPINKAAYTFAIGAIASGNFIPYAI
                     FASVKMVSAFGVTIATVLGRDLFSESEKEIGKQTWILGLAGITEGAIPFMIEDPIRVI
                     PSLVAGSAITGSIVAFFNIGLQVPGAGIFSLALLEGSMSGFIIASIWFFAAVLGAIIS
                     AVLLIITRKQKNQRKIH"
     gene            complement(12030..12755)
                     /locus_tag="KR231_001434"
     CDS             complement(12030..12755)
                     /locus_tag="KR231_001434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HBH0003817.1"
                     /translation="MEFYERAKKYEYKFTDTEDMIIEYMRKNKEEIVKLSIQSLADKF
                     FTVPNTIVRLCKKMEYDGFSQLKNNLKEELKNEDKEPKNGFESDIKKTLELIDYEKIN
                     KVADIIQKSRSIIVYGIGQNIPLCEILVKEIRGGHDNITYYSQRHEVLHDIGKLGEQD
                     MFFALSLSGETKEVIEVAKTAVNKGCKVVALTHICENQLQQIADISLYCYSTIKQVNG
                     YNISDKVPIMMIMRAIIEQYWLR"
     gene            complement(13018..13788)
                     /locus_tag="KR231_001435"
     CDS             complement(13018..13788)
                     /locus_tag="KR231_001435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ChbG/HpnK family deacetylase"
                     /protein_id="HBH0003818.1"
                     /translation="MKKLVVRADDIGYSEGVTLGIISSYKNGIVTSAGIMVNMPFSRQ
                     AIEMVKNDDVCFGLHVNLVIGEPCCKEHIKIKNLLDEGGKFVSSKIRRTQLLTGKEVF
                     NYEEVYEEVCAQIETYKLYMSKLPEYIDIHGIEEDVSISAMCDAAKEYGIPSCPYYLD
                     SCISMPSKYPQNDFYKLNKSFVKLFEEKYINLDKDITLMVTHPGFIDYSLIKSSSLIQ
                     ERVYEHAMLCDKEVKMWLKRNNIELVDFKDIFKSNNYI"
     gene            complement(13790..15217)
                     /locus_tag="KR231_001436"
     CDS             complement(13790..15217)
                     /locus_tag="KR231_001436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HBH0003819.1"
                     /translation="MMQQLSLLGKTMLVPIAVMPAAGILGLLFGPNMLNVPAISNISN
                     IVFSNVDYLFLLGAASAYSKSKDKTSVMVAAVVAYMIFKSNLELLNDTLNAGVFGGII
                     VGACIAWTYNKTYKVKVPAFLSFFAGEKCVITLSPVVALILSYIFSLLWIYPQAAMNQ
                     FGFWLGGAGAIGIFLFLFCNRALIPTGLHQVLNAYILFEMGEYTTSTGEVIRGEIPRF
                     MAGDPNAGFFWTGFYIIMMFSIPAISYAIYKTAQDKKKQEVKGAMTAGALTSFMATVT
                     EPIEFSFLFASPKLYIIHSFYSGLGGVVLYLLGVRLGSFNGASIIDYVLSFSYGDKAW
                     LVIPVGVVFFVLYYVTFKYIIIKDNVQTPGREVEIEIGDKVSEKEKNLKLSHGNFSYM
                     AKQIIKNCGGYENIVTLNNCMTRLRLEVKDATILNDDNIKKTGAKGVIKLSNTSVQII
                     IGTDVVKVKDEMEMQLDELRKQADA"
     gene            15608..16330
                     /locus_tag="KR231_001437"
     CDS             15608..16330
                     /locus_tag="KR231_001437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBH0003820.1"
                     /translation="MAKNKFSEIYEVLKEEILDGKYTSNMMLPTELQLIERFSCSRNT
                     VRRAISQLNTEGYVQSIKGKGVVVLENSCSNDFFLNMHNFKGVESIVEDKKVNTATSV
                     LHFSKILIDNKLSKKTGFKVGSEVYYLHRLRYIDNIPKILDINYFLCSIVKDLDVSIA
                     QGSIYKYIEECLGTKIVSSRKIFKIEKATELELKTLPLNDYNCVGVIKNSVYTDDGKL
                     FEYTESKHTPETFVFMDVTQRY"
     gene            16527..18194
                     /locus_tag="KR231_001438"
     CDS             16527..18194
                     /locus_tag="KR231_001438"
                     /EC_number="3.2.1.93"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha,alpha-phosphotrehalase"
                     /protein_id="HBH0003821.1"
                     /translation="MKNWWKKATVYQIYPKSFKDSNNDGIGDINGIIEKLDYLYYLGV
                     DLLWLTPMYVSPQRDNGYDIEDYYNIDPKYGTMSDFEKLLKEAHKRDIKIMMDMVLNH
                     TSTEHKWFKESKKSKDNPYRDYYFWKDAKPDGSVPNNWISRFSGTAWKYDETTNQYYL
                     HLFEETQADLNWENEKVREECYKILEFWADKGIDGFRLDVVNLLSKTPGLPDDPITGP
                     KGDGRTHYADGPRIHEYLHNMNQKVFKPKNIVTVGEMSSTTPEECINYTRENREELSM
                     VFSFHHMKTDYKGGAKWTNEMFSLDKLKKAQSDFQYKMYEGKGWNALFYSNHDQPRAL
                     SRFGDDRFFRQESAKMLAITLFGLQGTTYIYQGEEIGMTNAYFTKIDEYDDAESKNAY
                     YHMIKSGIDEKEALLILQQKSRDNARTPMQWDNTIYKGFSNHKPWLKVNNDNISVENE
                     LNDSRSVFYTYQRLIKYRKQYDIFTEGTYRLLDENHKNLFVYEREYKNQNLLVISNFT
                     HDNVVYKLPETYLNKLNYTILETNYTRDIIENKMEIKPYESIMIYYK"
     gene            complement(18290..19609)
                     /locus_tag="KR231_001439"
     CDS             complement(18290..19609)
                     /locus_tag="KR231_001439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HBH0003822.1"
                     /translation="MEKGIKLGFWSIVLLGINAIIGSGIFGLPGDAYTDIGPASILVL
                     VFCMLLAVSIALCFAEAGSWFDTDGGPYLYAKEAFGDFVGFEVGFMKWIVSMIAWATM
                     ANFFAVTLSSVWPQAAEPLIKNIIIGILVVGLGIINFMGMKQSKHLNNIMTIGKLLPI
                     VLFIAVGLFFIKGSNFTPFVIIQKGQSASSAFVAVSITLFYAFTGFESLAVAAKDMEN
                     PKKNVPKALVMVMFVVSVIYMLILGISIGVLGNGLAGSATPVADAAIKMLGPIGGYII
                     TIGTIVSVGGINIASSIFTPRSAAALVEQGLMPKSIRQTNKNGAPYIAIIVSVIGTLL
                     IAWSGSFTTLSQISVVSRFIQYIPTCLAVLILRKKYAGKDVNFRIPGGAIIPIFAVII
                     SILLLIKAGIDEPMKIVWGLGGMIIVVPIYFYMTKVYSKKYNDVEVK"
     gene            complement(19650..20396)
                     /locus_tag="KR231_001440"
     CDS             complement(19650..20396)
                     /locus_tag="KR231_001440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyl-gamma-aminobutyrate hydrolase
                     family protein"
                     /protein_id="HBH0003823.1"
                     /translation="MKKLAKKKYPIIGISGNLLIDEGGMFPGYERAYVNNDYIQSVVM
                     CKAIPYIVPIVYDDEIIKEQVSNIDALILSGGQDVNPLIWKEEPHNKLGAISPKRDSF
                     DMKLLKHALDMKKPVLGICRGEQIINVTEGGSLYQDLSLIEGAYIKHNQQHLSNVPTH
                     TVQIKEGTKLYEILGEKEVLVNSFHHLVVNKVAPGYIVSATSKDGLIEAIEKEGSEFV
                     IGIQWHPEMMTRDYDNMKKIFMAIVKEASK"
     gene            complement(20640..22649)
                     /locus_tag="KR231_001441"
     CDS             complement(20640..22649)
                     /locus_tag="KR231_001441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HBH0003824.1"
                     /translation="MKTIAVVTDGLSKLECFLNKNLEMIFKDKVMIKNYYLNKITEKE
                     LIKDDIILVMIDDRVLKIKKYVEDVSKIITINRSIKQKDIYKLFSLPEGIDVLVVNDN
                     KHTVLETISNLYNIGINHLNFIPYNPNEEYRNIKIAITPGESSLVPKYIEEVIDLGHR
                     YIDSSTFIQIIAKLKLDDKEITERLIKYTDEIISLYSGINTKYKELTIKADELNSIIN
                     LSNLGMAMVSDKGNIIICNNSLRDILDIQSNIIGKNIDELENENIKKIFSLSKAHDEV
                     IKFNNKYLNVNKYNIESFGRVTGYYFCIQEITYIRKLEQNLSKKLREKGQVARYTFDD
                     IKTVSTKMERTKKLGMKIAESDYTILITGESGTGKELMAQSIHNASPRHSQPFIAINC
                     AAMPENLLESELFGYEEGAFTGALKGGKKGLFEQANNGTIFLDEIGDMPIYLQSKLLR
                     VLQENQVMRVGGENVIDIDVRVIAATNKNLLEMIKGDRFRADLYYRINVLPINIPPLR
                     ERKEDIEVMLKHFMKRKRAISQDVQDIINAYEWPGNIRELKNTAMYINIMSSEDVILI
                     NDLPHNLLNITEDFSKEISILKDRTSIEKVKLVMECLKNANNLNKNIGRNGIVNSINE
                     LGYNITEGEVRGILNMLKELDLIICESGRKGSELNRRGKNILNSI"
     gene            complement(23043..24476)
                     /locus_tag="KR231_001442"
     CDS             complement(23043..24476)
                     /locus_tag="KR231_001442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HBH0003825.1"
                     /translation="MALRKDFLWGGATAANQCEGAWNLDGKGPSCSDMCTGGSQKVSK
                     RITRVIEKGTFYPSHEAIDFYHRYKEDIALFAEMGFKVFRFSIAWTRIFPTGMEKEPN
                     EAGLKFYENVIDECLKYNIEPLITISHYEIPFAITEKYNGWVSRDVIDLYMNYCETIF
                     KRYKGKVKYWLTFNEINSATMPMGGYLSQGILNEGTTDFINQVDIPQLRFQGLHHQFV
                     ASAKAVKLAHEIDSNYQVGCMQIFATMYPYTCNPDDAVKTQRDSRVMNYFCGDVQVRG
                     EYPTYMNRYFGENNIEIKMEKGDLEILKEGCVDFYTFSYYMSTCVSSDSKEDNTSGNI
                     LGGVKNPYLKSSEWGWQIDPEGLRYALNEIYDRYRIPMMVVENGLGAYDKKESNGVIN
                     DDYRIEYLKAHIEQMKEAVEDGVDLFGYTPWGCIDLVSASTGEMAKRYGFIYVDKYDD
                     GSGDLSRIKKKSFDWYKQVIESNGERL"
     gene            complement(24563..26479)
                     /locus_tag="KR231_001443"
     CDS             complement(24563..26479)
                     /locus_tag="KR231_001443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HBH0003826.1"
                     /translation="MRKYEQLSKEIIANVGGKDNISSLSHCITRLRFKLKDESIANDD
                     VLKKMDGIVTVMKSAGQYQVVIGNHVPDVYEVVCDLAGLGGDTIDNSDSDAPKGLLNK
                     FIDIISGVFQPILGVLCAAGMIKGFNAVFTALGLYGETDGAYIMLNAIGDAMFQYMPI
                     ILGYTAAKKFKLKPFIGMLIGAVLCYSGIQLDTLASTGQPLYNLFTGTIFESPVYITF
                     LGLPVIAMNYTSTVVPVILIVLLAAKLEKVFAKIIPDVVKNFFVPMAVLLVSLPLGFM
                     VIGPIATYASNIVGNGFLALFNFSPILCGALTGLLWQVLVIFGLHWGLVPIAMSNLMT
                     MGFDTILVGVFVPSFAQTAVVAAMYFKLKDKKIKELCIPAVISGICGVTEPAIYGITL
                     PRKTPFIYSCVGGAVAGAVMGIMNVKSYVMGGLGIFGIPNYINPTTGDMKGVYATIIA
                     IIVAIVVGFVLTLFFWKDDAIVEISKDDNGQGVIEKNKREVVYSPIKGEVKALEQIQD
                     AAFSTGILGKGVAITPKEGKVVAPFDGTVMTLFPTKHAIGIISDNGCELLIHIGLNTI
                     QLEGKYFKSFVNQGDKIKKGQTLITFDIESISKEGYCLETPVVVTNYSDYVDIVENTQ
                     KHVNNSQKLITVLA"
     gene            complement(26553..27413)
                     /locus_tag="KR231_001444"
     CDS             complement(26553..27413)
                     /locus_tag="KR231_001444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439998.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HBH0003827.1"
                     /translation="MIIEKILNNNVIITTDENHKEIVVMGRGLAYKKRTGEHISKDKI
                     DKIFKLSDPNISDKFKELIADIPIRYMELSDEIILYAKEKLGKRLNDSIYISLTDHMY
                     TAIERAREGVSVKNVLLWDIKRFYKSEFKIGLEALDYIEKKFEIRLSEDEAGFIALHI
                     VNAQMDQSIKTIYEITQIIQEISNMVKYHYRIVFDEDSVYYHRFITHLKYFAERIVSN
                     NLHENNEDDLLNVIKVKYKNAYKFIEKLDEFIHKKYNYDLTDEEKLYLTIHVERVVSK
                     SIKSDINPNN"
     gene            complement(27764..28951)
                     /locus_tag="KR231_001445"
     CDS             complement(27764..28951)
                     /locus_tag="KR231_001445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallopeptidase"
                     /protein_id="HBH0003828.1"
                     /translation="MIESIKKRAYEIENELGKEIEEVCNFIFNNPELGEEEYISSKYL
                     VEKMKEYGFDTVYPYCNMETAFRAELGDNDGPTIAFLAEYDALPGYGENKEPAHACGH
                     NWIAASTLGACIVLSKLKENFKGKIVLIGTPAEETTGGKCDLVKAGAFDDVDVSYQMH
                     IEAFNNINCKALAIDSLEFSFEGVSAHAASHPHMGVNALDAVQLTFAGINALRQHVKS
                     DVRIHGIVSNGGEAPNIVPEKAACKFFVRAAERSYLDEVTKKVINCAKGAELMTGAKL
                     SYRYFENSFDNIINNKVLQKITKNNLIEAGITDILEGKDGPVGSTDIGNVSQVCPTMY
                     TEIALDISPMVYVHEKEFLNYANSEEAYDKLHKAVKAMVGCALEIYLEDGLLDEIKKN
                     HLN"
     gene            complement(28965..30356)
                     /locus_tag="KR231_001446"
     CDS             complement(28965..30356)
                     /locus_tag="KR231_001446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfcC family protein"
                     /protein_id="HBH0003829.1"
                     /translation="MSSLKKKKFTMPQTLTIIFLLIVLMAILTWIVPSGNFERVDIDG
                     RSVVVAGTYEKAPSNPQGITDVFTAPINGFIDAAEVVGFVLIVGGAFGIVNKTGAIEA
                     VIAHTVNKMKKFQFLIIPISMILFGLGGTTFGMSEETLPFYMIFIPLMTSMGYDSLTA
                     VATVFIGATAGFGAATTNPFSVGIAQALSQIAPGSGIEFRVVMFIIYMAISIGFVMMY
                     ANKVKKDPKKSLVHDISLNQESMVNSDTNIKEFTKREAMVIAIFTIGMAIMIYGVLKL
                     GWYITEIAMIFTAIGIISGIASGLKQDDIVNSFISGAGDLMTAGLCIAFARGIVIIAE
                     NGFIIDTILNSAANLLNGLPKTIFINLTFLIEGLIAFLIPSASGLASLTIPVLAPLGD
                     LVDVSRQMIVTAYQFGIGVTNLITPTSGVLMGALAVANIPWSKWVRFVIPLMVVLTIL
                     VMAFLTIGLYLGF"
     gene            complement(30951..32651)
                     /locus_tag="KR231_001447"
     CDS             complement(30951..32651)
                     /locus_tag="KR231_001447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HBH0003830.1"
                     /translation="MHYIAWHFNKNGGNNTMKDKLQVLSGAMMIPVILLVVAGVFIGL
                     GSAFANMENVSALGLSGLIKEGSFINVFFKVINDLGFMVMRYLPIFFVTGIAFGLSKK
                     EKGWGALGGIVLFIGMHTVISTLLAANGINSDTVTAEAFMASGLGEAEAYSRSSLYGS
                     FLGIFSYDCSIFGAIIAGFVASAVHNKFVDIELPSALSFFSGPRFSMIMMFIASIVLG
                     TAMYFIWPPVGLALSKLGNWIGSSGLLGTFTFGAMDKALLPFGIHHLIAFPIEYTRVG
                     GTMEVGGAIYEGVNNIRLAQMGDPDTLSYITRNFTTGRLLIHFAILPAAALAMYKLAD
                     NANKKKAISILIPAIVTAMLVGVTEPIEYTFLFVAPLLYFVAYVPLAGLTYVFTEMFN
                     VSIMGESFRNMFPNLLQPQKVDALPLLFLIPIFFIVTYIIFTWAIKKFDIKTPGRSSE
                     EVKLYSKKEYRERQSVDAGKTAYNNAVEEEVDDKDTKLVHSIIEGLGGSNNIKNVTNC
                     ATRLRVELNSIDGFYEDGFWVNELGASGVVKKKNSVQVIFGPRVITIASKLKAVLGVD
                     "
     gene            complement(32623..34026)
                     /locus_tag="KR231_001448"
     CDS             complement(32623..34026)
                     /locus_tag="KR231_001448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallopeptidase"
                     /protein_id="HBH0003831.1"
                     /translation="MIVNKELIIDYLKSNQENIINDIRSLVEIPSIRDESTTDINQPF
                     GIEIRNAFDKLIQIAKDKDFVVKDFDGYAIHIEYGEGEEVVGVLNHIDVVPIYNKELW
                     KSKPFKVCQKDNYLYGRGVNDNKGPLIGILYALLFLRELNEKPKRKIRLIVGGAEETT
                     WECMEHYFSVNEQPKFAFSPDGNFPIVNGEKGILYFNLRKKIDKDKFRNHNLVDIKSN
                     KEDGFVCDKIEAVFKTNDKKDLVESLAYYTEIEELEEGKVLVRYTGERALSRNPHRSY
                     NCAFSLAKDLEKIKKLNDKGVIIRDILNSYFTDDNHGKKLGIYKEDVDMGVSTICIMS
                     IFLEKNELNMKIDFRYPKGISWEFITNRINEIGKKENLIVDIYKDLKLLYVKPDSELI
                     NKLSNAYKQGFGKEAELFTKGAASYARVLKNGVAFGPTIEGDNPNSHQANENISIDTL
                     YKAIEVYIYALYSLAFQ"
     gene            complement(34290..34781)
                     /locus_tag="KR231_001449"
     CDS             complement(34290..34781)
                     /locus_tag="KR231_001449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HBH0003832.1"
                     /translation="MFNIFKKKENKIEKIYSPFKGNLVNLEDVPDAVFAQKMMGDGVA
                     IIPSEGKLYSPVDGEIVNVFDTKHAIMIKSNDNTNILIHVGLETMSLEGKPFDVKVKA
                     GDKVKAKDLIMEVDLDFITSNDLNIITPVVIMDDADSVKRTVKDRIEPGNVDINSIIM
                     EVE"
     gene            complement(34807..35619)
                     /locus_tag="KR231_001450"
     CDS             complement(34807..35619)
                     /locus_tag="KR231_001450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HBH0003833.1"
                     /translation="MRYKLICTDMDGTLMGKGFEVSEENIKALKEVMEKGIKVALVTG
                     RPYNAMKYFTSVLGDDIYIISTNGTYFKLLGYEYKKVLSKEALKKIYTIGEKYNLSKH
                     FKGCKIVISNNEIGEEHPYRLINSKNKEEDRIEIIENASCETLLEKADNEILKCILFS
                     ENVDSLREAKEEFKKQEDLEVVSSGKINFEVMSKGTSKGIAVKKFCDILGIDSKEVIC
                     IGDNENDISMIKFAGLGIAMGNATDEVKSMADFVTDTNVNDGVAKALRKILS"
     gene            complement(35632..36783)
                     /locus_tag="KR231_001451"
     CDS             complement(35632..36783)
                     /locus_tag="KR231_001451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase"
                     /protein_id="HBH0003834.1"
                     /translation="MINFYQPSRINFGQGTLSELPRIIGKYGKKCLLVTTPNVEPLDK
                     LYKRVTLNLIEKGIEVVHFDRVEPNPTVELINEGFELAKKESVDVVLAVGGGSSIDTA
                     KVLALTFGLEKIDWDYMFSTYTNPFKIYDKVSEKELPLIAVSTTSGTGSQVTQAAVIS
                     RGSEKNTIFHQNCFSKECIVDPELMLTLPERITASTAFDAFTHAFESYINPNANDFTE
                     IMSEKSMELVINYLPKVMEDKNNIEYRTKLAVADTLGGSSLANAGAAAPHPLSEIIGG
                     VTHIPHGEALAIVFPKFAEKFYKDNIEKFAKVARMLNQELEKVEDDEAAKTLGNEIES
                     FLKRVGLKTKMSEFNVTKEQLEQITSCPVLGFLPFGKKEDLVEILEKSY"
     gene            37053..37694
                     /locus_tag="KR231_001452"
     CDS             37053..37694
                     /locus_tag="KR231_001452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldolase"
                     /protein_id="HBH0003835.1"
                     /translation="MKYLIDSANLDEIQKCLKYGFKGITANPSMYLKEKVNFHEFIET
                     CANLNPEILTAEVIGNNLYELINSCDKILNINKNTIIKINFSEVGLELINILNSKGVK
                     TACTLIFNVNQASLAINAGADYLFPFIGRNDENGNDGIKNLTEICNLISINGYNTKVV
                     AASIKNVFHLTQASLCGCDYAAVTYDLFKKASFNQLTIDGANTFERDWSKVNK"
     gene            37720..39264
                     /locus_tag="KR231_001453"
     CDS             37720..39264
                     /locus_tag="KR231_001453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HBH0003836.1"
                     /translation="MNKRLLDIAELLLNSSDYITVDTIAEELKVSNKTIRNDLVILDE
                     WLLEFNLSLDKKTGSGVIILGNEDIKLKVIRDINDKSNCIYAYSPEDRKRYILSKLFI
                     KNSKFRIRDICNELHVSRATVHKDLVVIQNFLQNFKVTLVRKTNNGVYLEGKEKDIRK
                     AIFELATVNKSYTELKEILFSKSNECKDTPSTKIFKELFNYDFEKLSQITLHTLQVEK
                     SNLSDEYYINFLIHIAICIKRISIKRYINLSEGFFRELLEHEYFEKSKILCANLSEAF
                     DVEFIDEEVCYILLHIEGLLKSIKKTTTLEPLKNEEITEYNLSEAIAVHWGSILNLNL
                     KDDLILIKSLANHLKSVLHRINYGFTITNPILNDIKRTFPYTYKAAKESNTVIKQLMN
                     YEVNDDEIGYLALYLISAIDRSKSPLNTILICHCSDGVSNLLVQKLSFEFNQINIVKS
                     IPLSSISFTNFDDVDLILTTAPVDFEHNAELININALLSKNDISRLSTIIKKLYSEKN
                     KILSYK"
     gene            complement(39464..40090)
                     /locus_tag="KR231_001454"
     CDS             complement(39464..40090)
                     /locus_tag="KR231_001454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HBH0003837.1"
                     /translation="MKKEMIKDYLLITISAFLMALAVNFFFAEHTLAPGGITGLSVVL
                     STFLSMPVENISLGISMPLLVMGLLFLGKGFGIKTLYITLMGPLFLKVIPQTHITDNL
                     LVAGVIGGLLVGTAIGIAIIRGCSTGGTDLVAMLINKVIKFLKLPVILFMLDGFIIVA
                     SGIISKNFMISIYSLISLLLIIKTIGFVTTKFGKNTEEINNINNACAQ"
     gene            complement(40225..40941)
                     /locus_tag="KR231_001455"
     CDS             complement(40225..40941)
                     /locus_tag="KR231_001455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pentose-5-phosphate 3-epimerase"
                     /protein_id="HBH0003838.1"
                     /translation="MKHIKIAAGLAHVNYGHISAVVKEAMDAGVDYVHSDAADMHDLK
                     NMQLMGGHQIIEAIRPVTDKPIECHIYTRDCDRLFIEKIAAAGCNLLIIPAEHFLGAP
                     LAYIINYCREFGMKVGLTIGCYTPLCFVDEAIYDIDRLQIVVHGVDETDGKDNWGWRK
                     SAVDLVKRARKMIDEKNPKCELAIDGGLRADNMEPLIECNPDVVILSSAIFKDKDGIT
                     AGVKNCRKAIDKAATKFGLE"
     gene            41367..42581
                     /locus_tag="KR231_001456"
     CDS             41367..42581
                     /locus_tag="KR231_001456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phosphofructokinase"
                     /protein_id="HBH0003839.1"
                     /translation="MRNCIIAQSGGPTAVINASAVGIYEKNLETKYFDKVYFGINGIE
                     GILNKNIIDSDSLNKDNVLNLKQTPSSGLGSCRYKLADYKINSYDYDRVINILDEYEI
                     DTLFYIGGNDSMDTVMKFSQYCKNTTCKIKFIGIPKTIDNDLLGTDNCPGFGSAAKLI
                     STLIMETYLDFSIYKNNGIFIVETMGRDTGWLAASSSLARLNDTPLVDLIYLPEIDFY
                     EDKFIEDVRKIFKEKNKAYIVASEGIRDKYGNFICEQKTSAHDKFGHSQLGGVSNYLK
                     NLIVSSSITTRVKTLELGVIQRCAMHLASDTDLKQAAEVGAYGIELSKKGYTGVMAII
                     NRTCNNPYKYEVSHTDISKIANKTKYFPKEWINEECNYITDEALNYLYPLIQGKPDIK
                     YKNGLPYFSIIY"
     gene            43201..44529
                     /locus_tag="KR231_001457"
     CDS             43201..44529
                     /locus_tag="KR231_001457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0003840.1"
                     /translation="MMKIAVITTEFLKEFVDNSIKKLNINAEIEIYIYRDFSHVGDLY
                     LEIEDRFDGFAVSGPIPKKAITKKAGTIKKPLVDFGTDLQSYYDMFLKLIFKYNTLDF
                     SRAYFDLTDWADNPKDISYYLSNGTFGDLMDSIDENASKMSLSDIAKLEKKIAKKHIN
                     LWNEGKIDFSTTRFSSIVPMLQNAGVNFHFIYPDIDLLKNTFNNLIKDIHLHRMKGNQ
                     PSVIYITVKDTNYDDSTLDQVYKILNSIKKDKLTDFIIEKNSNSFKIFTKCETIKSLT
                     KNFTACYIKESIENSTNIKVCVGYGIGNDIKQAMSSAISANKESKINHLNYSFLVNEN
                     YETIGPLLCDKLLTVSNKVTPHINTIAKSSKLSTLTIQKIISVTEILQRDEVTPKELS
                     SCLNVTVRTANRFLSSLLKSGNATILYEKQNSTKGRPERVYKLFISENKY"
     gene            complement(44657..45847)
                     /locus_tag="KR231_001458"
     CDS             complement(44657..45847)
                     /locus_tag="KR231_001458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HBH0003841.1"
                     /translation="MKNFFKEAQSIEGEIIRWRRYLHENPEIGCNLPKTVTFVTSTLE
                     KMGYSPKLTSNNGIVAVLDSKNGGKTLLLRADMDALPIMEETDLPFKSKNKDASHSCG
                     HDNHTAMLLGAAKILMDNKHLLKGRVKFVFEPDEETTRGAKSMIDDGILENPQVDAAM
                     AFHSMVGKFLNTGQVAYSRGPAMASADIFEITVEGKATHGASPEFGVDPINIMSHIQI
                     ALNTILSREKPQKEPVVLTIGMFNAGSVPNAIPNKASMSGTLRTFDQSVREKLKNRII
                     EISTGIAKSFGGNAKVEFKMGTPAVINDLDVGDEIVSYVKEVIGNENVIDFPSAMGSE
                     DFSEILLRVPGVFLWIGMGSISQGYNFGMHNPKAIFNEEGLVYGSALFAHCAVKWLEN
                     NFSR"
     gene            complement(45953..47332)
                     /locus_tag="KR231_001459"
     CDS             complement(45953..47332)
                     /locus_tag="KR231_001459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HBH0003842.1"
                     /translation="MIGSISINEIDKKRFKLDDLSKKIWENPEKAFKEFKACENTANF
                     LRSEGFDVEVGVGGLATAIRASFGSGKPVIGFMGEFDALPGLNQKVSTKQEAFELGAY
                     GHGCGHNLLCTAHVGAVVGLKREMIENNLSGTIVFYACPGEEQLTGKGFMARGGAFEG
                     LDLAINFHPNKISEATIGTSTAVNSVKFHFKGKTAHAGSDPQNGRSALDAVELTNVGA
                     NYLREHVTSDVRIHYTITDGGVAPNIVPDKASVWYYTRALSREAVESTYERLVKVAKG
                     AAMMTETEVEVEFLGGCYNTLNNHVLANLVSECMNEIKQEPWTREELDFAAELDRQSP
                     QQYKAMISKYNLPEGTHLYYGGGNVTNFNSYGSTDIGDVMHIVPTAYFFTGCTNLGAP
                     GHSWQFTSCAGSSIGEKGMIYASKIMAMFGAKILNNPEIAKKAKEEFDKSMNGKTYKC
                     PIPDDIPTP"
     gene            complement(47363..48571)
                     /locus_tag="KR231_001460"
     CDS             complement(47363..48571)
                     /locus_tag="KR231_001460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0003843.1"
                     /translation="MENFWNPLTCFTVCVMIYAFSEFLSKKTKGAISTLLFVCIIFLL
                     GFWTNILPKDITGASGILAAMSNFGIALLITNLGTLINLEDLCHEWKTVVIALVGIVG
                     IGVGCLTVGSMLFGREYALIAAPPIAGSTVAGIIVTTVAEAANRPELAAFVILVLSFQ
                     KFFGIPITTYCINKELKFKRDNGDFLKDESKSNFKLPSMRIFKEDLGKKSSTLVYLAK
                     LSFVAMIGNFVGLATLIPGFTPANYYLNPNIACLLVGLIFTRIGFLEKGILDKSQSNG
                     IIMFGCMLMLPGGLAKVTPTALFGMIIPTIGILVVGSVFIILFTAIVGKLLGYSPRMS
                     AAIGVTCMLAYPATQIISNEGIDAMEGTEEEKQRATDYLLPKMIIGGFVTVTIASVAF
                     ASIIGPIIFG"
BASE COUNT        16128 a         8590 c         5541 g        18533 t
ORIGIN      
        1 aattaataaa tcattttatt tacaattata acccccctta taaaactata ttaataatat
       61 atacagtatt tataaggggg gttgtttata tttaaaaact atttactttt cttttaattc
      121 ttctccatta gttcttatta cattttgata ccaataaaaa ctatcttttt tataacgttt
      181 tttacttcca tttccattgt tatctatatc tacatatata aatccatatc ttttttccat
      241 ttcttgagat gaacaactta ctatatctat tggtgaccac atacaataag ctaatatttc
      301 ggttccatca gctatagctt cacctatttg ttctatatgt tttcctaaat aatctattct
      361 gtaactatca tgaacttttc catcttcaaa tttatcatgc attccaaatc cattttcagc
      421 tatcattatt ggcttttggt atctatcata atattgagat aaagtattgt ataatccttt
      481 tgggtcaatt gcccaccccc aaggatttgc ttttaaatat ggattcttta tattgtcagt
      541 tggattcatg gtgtttttac ttgctgatac tgttgtagaa taatagtatg ataaagctag
      601 aaaatccata gtattttctt ttaagatttt atcatcacct tcctccataa ctatatttat
      661 gttattttct ttgaaaaatc tcttaatata gactggatac tctcccctaa aacttacatc
      721 agtgaaaaaa tattgtagcc tatttctttt taaagcaaat actacatttt cagggtcaca
      781 atcttctgga taagatgtac aatctgccat catcatacct atcatcatat ctgaatttat
      841 ttcttttcca agcttcttag tcaaagctgt agctatgaat tgatgatgaa tagcttgata
      901 tctagtctct tctacattat ctacttggtc tacacaaaat gcaactgaat taaatgattc
      961 ataatgtatt aaatttattt gatttataac tatccaatat ttaactttat ttttatatct
     1021 atttagtatt aattctgcat atctaacaaa gaaatctacc acttttctat tagaccatcc
     1081 tttatatttt aatactaaat tcaaaggagt ctcatagtga agtagtgtta caataggttc
     1141 cataccatta tctattactt catttataag attatcataa aactttaatc cctcttcatt
     1201 aggctctaaa tcatctccat ttggaaatat tctagcccaa tttattgaaa atctaaaaca
     1261 ctttaaccct agctctttca aaagctttaa atcttctttg tatgtatgat aaaagtctat
     1321 tccactacgc ttaggataat atccattatt atctttcata gcaaacttta ttctttctat
     1381 agtcatatca gactcataag gtttagatat atctctatct ttatcataca tatgtacatc
     1441 agctaaacac caacctttgc caccttcatt ccatgcacct tctaattgat tagctgctac
     1501 agctcctccc cataaaaaac ctttaggaaa cttacccaat ttaatcactc cttattttat
     1561 ttatttaaat catttactat tatttacctt atattctata gactttacta ttcctactaa
     1621 agacatagtt atatttaact cgctgaatat ggtcataaga gtatcttgag catgtgcaaa
     1681 taacagcgaa tgtgctcttt tctctccacc agcttcccct tgtataatct tggtttgagc
     1741 tctatgtgct tctgtcataa acccttttgc tttagctagt tttaaatcag catttctata
     1801 atcaaacttt tccaaatcat taagagcatg tttaatttct gttctagcct cacctgcacg
     1861 aagtattatt tgcattgcca cctctactaa ttcttcatct attatatgtt cttcaattgt
     1921 catatttata atttcctttc aatttctaaa tttaaacctc ttggctctct aattttatct
     1981 cttctttctc ataagcttta aaaaatggat accatatcat aaatagcaat actatattta
     2041 ttgctaaaac aataagacct ctaacatctt gatttaccgt aaaagtagat ataccaaaag
     2101 gaacatacca taaattaaac accttacttg gaattgtcac aaatcccata ctcattgata
     2161 agtaagtagt tattgatatt actactgttc ctatccacat aggtaacatt aaaaatgggt
     2221 tccatgccac tggagctcca aatattactg gttcatttat attcattata gaagggacaa
     2281 tacatgctct tcctattgct tttattcttc caactctgga taaacacatc attataacta
     2341 atggtaatgt agcacccaac cctcctaaag ttatccaacc tgtttgaata acttcgtaaa
     2401 catatatatt agttgctact cctcctgatg ctactgctgc tgcattagct gcaattgcac
     2461 caagttgaat tgaataagtt ataggagata gtacccaccc acttattcct aaagaatata
     2521 taaatactac taaaaagttt aagagtacaa atccaggtaa tgtctgtgct atatctgata
     2581 ctggtttaaa tactctaact attatttcaa acatgtcaaa gttgagtcca taaattaatc
     2641 cccagcctac aaacattatc actgttatag gtaacatatt atcaaaccac ttgcttacaa
     2701 aatccggaag tgctgaatct tctccgaaaa atgaaaaaga accaaataag gacattatta
     2761 atccagagaa taatcctgca actagcgata caagcattcc ttctcctcca aacctgttga
     2821 agttaaatat agctccttca ttcgtaatct ctggacgaat catcattaac attaatccag
     2881 cacctgcaag accagcgact acactcatac tttcaaattt cttattcttc attatttcca
     2941 taggcaataa aaatgctata aataatccta aaagtccaaa tgtatattga tttattggac
     3001 ttaaatcagg taaaaagctt atgtaattct tcaagacaga aactatagtt actaatgagc
     3061 ctacaaatac cattggcaaa actttcatta tagttgattg aactgattgt acccatatat
     3121 tcttagtcat attatttaca acaggagtaa atttttcact taaaaaatct ataaatttat
     3181 tcataaacac tctccccata aatattttat ttgtttgata ttagttctag tgcttcttcc
     3241 aaagcctttg ccccatctag tcttccatat gcagttttag atatacatgc tactggaacg
     3301 ttatattcat tagccttttg ttgaatttct tccttcatat aatctaaatg tggtcctagt
     3361 aataaacaat ctatttctga taaatactta tctatctctg actcacttct cgcttttata
     3421 tctgcttcta tacctttttt ctttgcactc tttctcatac tagttgccat aaaacctgta
     3481 cttgctcctg aaccacacgc caaaagcact cttatatttt tcataatgat acctccaata
     3541 tttttatcca tcaatttatt tcttaatgaa ctttttattt tattatgttt atattgtact
     3601 taccaaataa gttcatttca cataaatata tttcctaata ataggaaatc agttactctt
     3661 aattaaacat attaatatag tataatgtat cttataatac gtacattcaa ttatataatt
     3721 atcatatcat ccagatttta ttttaaaact atgcgaggga atctaatgaa aacatctaaa
     3781 aaagaactat ttttaaattt cataaaaaca caacatgatt ggatagattc atctacattg
     3841 gctaattatc ttaatgtctc aacgcgttca attagaaaat atgtaaacga aattaattcc
     3901 aatggtgaat ttatattatc ctctaaaaaa ggatataaag taaatctcaa taataattgt
     3961 caaaccaagg ttgatagttc agaaaatata tcacctgata acaggttaaa tttaatttta
     4021 aaagaactta tagttaatag taatggaatt aatatatttg atttaagtga agacttgttt
     4081 gttagtccag ctactattga aggagatata gtcaaagcta ataaatttat aggaagttat
     4141 aatttaaaga taaagcaatc gaaattttta ttgaaactaa ttggaaatga gtctgcaaag
     4201 cgcaaattaa tgagctctat aatatttaaa gaaacgggaa gtgatttttt aagcttattt
     4261 gatgtacaaa aaatatatca agagtataat ttgaccaaac tgaaagaaaa tataatatat
     4321 atattaaaaa aatacaattt gtttataaat gagtatgcta taaataacat acttcttcat
     4381 ttaatgataa ctatagacag aataaaaaag aataactaca tagaatctgt cgaagtagta
     4441 aactacatag ataataataa tgatataagc atttcaagag atatatcaaa ttttttagag
     4501 tctgaataca atataacttt aactagtgca gaattatact acttagtatt tcagttaaca
     4561 aacaaaacca cagtcttaaa ttatcatgaa atggatacta agtcattgcc aaattatata
     4621 gatgaacatt ttgttaaatt aactaaaaaa ataattaaaa atgtatatga cttatacttt
     4681 atagatttat ctgatgatga atttgttgta aaatttactc ttcatgtaaa aaatttaatc
     4741 agtagggcta aaaataatca agttttgaga aatcaaatac ctcagaagtt aaaagattcc
     4801 taccctctga tatatgatat atctgtttat atttgtaatc agattcaaat tttagaaaac
     4861 atagaaatag atgaagatga aatatcgtat atatctcttc atgtaggttc attttttgat
     4921 agacaaaaat tactagaaga taaaattctc tgtgcattaa ttactccaaa ttactatgat
     4981 ttacaattca aaatagtaag agaccttgag aagagattta atgaatccat agaaattatt
     5041 cagatttttt cagatactca taatcttgat tttgacaata aggtagacat ggttattact
     5101 actttaccaa ttagcgatag atgccctata ccttttgttt atgtaaatcc ttacctaaat
     5161 agaaaggatt atgataatat tcaaagtaaa tttattcaga ttaaagatag aaaaaatata
     5221 cttactgtac aaaatcattt agaaatgtac tttagtgaat ctttgtttat gaaaaatata
     5281 tatttagata gtgctaaaga ttatataaga tttatgggaa atattctgta cgaaaataaa
     5341 tatgtcaaac ccaattatat agatgatgtt cttataagag aaaaaatgtc ttcaactgca
     5401 tttaataaca atgtagcaat tcctcatagc atgaaaatgg atgctttaaa aaccggagta
     5461 tgtttaattg ttaacgataa accagttaaa tggggtgagg aaaaagttca aattatagct
     5521 atgataccta taaatgaaaa agaaaaagaa aagttcaatt acatatttga aagctttatt
     5581 gaaatattat ctgagtggaa taatgttaaa gaacttacta aggcagataa ctatagtagt
     5641 tttatgaata gaatagctta tcttattcaa aatatctaaa tcaattaatt tatttccaat
     5701 atatgtttct taagttatta acataaaata gataagctgt cacactaaaa agtctaaatt
     5761 aatatgtgac agctttttac ctaatatacc ttgttttaat actacatatt ttttgactgt
     5821 tgtatactag ttataagatt gaatatttgt gttgttgtag ctgtcatatt ctcactagca
     5881 gttgctttat ccattgcttc ttctattgtc atagctctat ttactataga aaaataagca
     5941 tctataccct cttcattaca tttaactgca tcttctgttg tggctccagc caaacctatt
     6001 acttttaccc catatttttt tgccagtttt gcaactccta ttggagcctt gcccatagca
     6061 gtttgattgt ccaatctacc ttcaccagtt atgacaaaat ctgcatcttt taactcttcc
     6121 tctaatttaa tttcttctaa tattattttt attccagatt ctaattttga atttaaaaat
     6181 gctaaaaaag caaaacctaa tcctcctgct gctcctgctc cttctacatt agctacatct
     6241 ttacttaagt aatttttaac tactttggaa aaatttctaa gcccattatc taactcctca
     6301 attatttctg atgttgcacc tttttgagac ccgtatatgt atgcagctcc atttttccca
     6361 aacagcggat tatttacatc acaggctatt ttaaacttac attcatctaa ttcctttaat
     6421 ctattttcta tttttatatg tcttatttca tttaaaactt ttccacctaa tcctactaac
     6481 ttgttatttt catcataaaa ctcaaaccct aaggcttgaa gcatacctat cccagcatca
     6541 ttagtagcac ttccacctat cccaactata aaatttctat agcctttatt tattgcttct
     6601 tttattattt ccccaacacc ataagttgta gtgtataaag gatttctaag ttcagtcgga
     6661 accaatgtta gtcctgatgc ttgagctatt tctattattg ctgtacttgt attttttaat
     6721 aatccatatg ttgcatccac ttttttagct attggtccag taacttctat agtatctttt
     6781 ttaccattca tcccttgaac taaggcatct actgtccctt caccaccatc agcaagtggc
     6841 aatatcttta cttgcgcatc ttctttaacc ttcaatatcc ccttttttat tgcatttcct
     6901 gcctctattg aagataagct tcctttcaaa gaatctatag aaattaatat tttcatattt
     6961 atctactcct ttttattact ccttatttta aacatataat tttataagct taatttatct
     7021 tttattttat actctacatc tctctttgta tacaacttat accattaata ttcttttatc
     7081 ttataaaaag ggagtgtctc aaaataaatt tcttagttca tgagacactc tttttgtata
     7141 aaatcaaata tatgtttatt atttcaacaa tgataaggag gattatctct attttaagat
     7201 aattcctttt tagcactatt taaccagtat agttttaact tggttcatta agcactctac
     7261 atttacagag ttattatcta ttgatataga ttctaattct ttttcattta ggttaatcca
     7321 tttagctgtt ttaatatttt tgttaaatac tatgttagct gattttgttt cttctttaga
     7381 attgtaaaat ctaactacta atgcctcttg tttttcagcc ttttttacaa cacttaacac
     7441 aaggtcctta ttagtttcct taagtaaact atatgaataa tctacttcta tttctgattg
     7501 attcaatttc atagcattat atggcatttt attataagtt tgtatttttg ttaaatactc
     7561 tttagccata tttgcaacat ttgcttctag tgtagatttt tcatgagtaa ctattgctaa
     7621 gtctattttt atatctccta tcatttgaga atctggagta ggcaacttta ttcctgatgg
     7681 acgacctggg cgtcttgcca tttcttcttt acctaggaat cctacacttc taaataatgt
     7741 tatagctatt gtgtcaaatt tttcccctac tatttcaaac tctcttgtac tgtttgtaag
     7801 aacagctact ccatgctctt tgtcagacaa tccaacgaat gttagcattg gatatataga
     7861 atctggtctt tcactccatt cttcctgttg ccaaacttcc atagcatcat catacacact
     7921 tctctttata tgtccaaact gattatcaga cacagaaaac tttgaagcta tatttgttgg
     7981 tatataagtt ctaaccctac aatctcttgc ttggttattt atgttgaata ctacatctat
     8041 tatagcttta tcatttggaa catttataac tatatcaaag tcaataaatg aatctgctct
     8101 attatttttt ctagcttgta tatcttttgg tacttttaat ctataattta tctttatctc
     8161 attattaaat ctatttttct ttatagtgga atttgctact atattatcgt taaatattaa
     8221 tttctcattt ggaagtggtg aaaaatcata ctcatctcct tcatctcctc cattttccat
     8281 caataataca ttttcaaaag ttttatttaa ttttttatca aatatcttta atgtcccgtt
     8341 ttcattaact tgaatagtat aaaagtcatt atctaccatg tcacatactt cataagcttt
     8401 ttctaacata tgttcaactt cttttatcat atacgcctta taccccattg caggtatttt
     8461 atctttaaag tttattgtat ataccataaa tgaatcatag tttccataat gaacaatttg
     8521 acggtctatt aatcctgcat ctattacttc tttatgtacc acttcaaaat ccaacttatt
     8581 attatcttta tcaaatattt caaatgcttt cattttagtt ataacttgag cgcttactat
     8641 ttcattccta tcgtaaggca ttaagttaaa tgctactaac ttatctaaag ccatttcaca
     8701 actcattgca tcaactattc ttcttttgta aaatgttatt aattggtcta ctttttcctc
     8761 agctaagaaa aatctattca ttatttcatg gtgaacttta tctgaacaac aacatccaat
     8821 gctgtcatga gcatgatttt tcattatttc tttccaaatt aactctatta atccatgatg
     8881 atattcaaat cctagagaat atgcaataga agctagtggc tccaatatgt tggttatctt
     8941 tgattctatt ctagcatttg ctgattttat atccattctt gttgagaata tacttctatg
     9001 aaccctcata tatttcccat ctaaaaattc cccttttatt gtatctatat cctcattttt
     9061 ttctagctct ttaaatatgt tttcatatct acttaagaaa aattttctct ctggataaca
     9121 ttcttttaat ttatatataa cttcaaatat attcttttga attggcattt ggtcatgtcc
     9181 atttggaagt attatatggt cagtagttgc acccttatca agaaccggta aatatttatc
     9241 cattcttgtt cttagctcat cttcattcat tggtagatat tttcctattg cataacctaa
     9301 tggaagtatt tgaaccaaaa cagaagaccc atcatcactc ttccaattaa actctgtttt
     9361 attagttcct tttctttcag aacatcctct ccaaaacatt gagtatttta tatcaaaccc
     9421 atttagtatt tgtggcattt gagcactttg accaaatgaa tctggtaaat atcctatttt
     9481 catatattct ccaaattcat cacaatcttt tattccatat agtaaatttc taagtatgga
     9541 ttctccacca actaccattt catcagtttg agtataccaa ggacctatta ttagccttcc
     9601 ttcttgaact aattttttta ttctctcctt acattcaggc ttaactgcta aataatcttc
     9661 taatatagca gtttgaccat ccatcacata atatggatag ttatgattat tttctaacat
     9721 atccattatt tcttccatat tatttacaag taatattcta gattcctcag ttgagaagta
     9781 ccattctcta tcccaatgca tatgaggaac tatgtgtaca ttttttttca ttgcttatcc
     9841 tccaaaactt atctgataat attttctgtc taattaaaaa tccaataaaa atactactga
     9901 gtttacaaaa ttttttaata tttattttat cactataatt aaacctttga tttaaatatc
     9961 taataacgta tcttttaatg tatctttctt tgattttttt gtttcctagt tattattaat
    10021 aatactgctg atattatagc tccaagtact gccgcaaaga accatattga tgctataata
    10081 aatcctgaca tacttccctc taaaagcgcc aatgagaata tccccgctcc aggcacttga
    10141 agacctatat tgaagaatgc tactatagac ccagttatgg ctgaaccagc taccaatgat
    10201 ggtataacac ggattgggtc ctctatcata aatggtattg caccttcagt tattccagcc
    10261 aatcctaata tccaagtttg ctttcctatt tccttttctg attctgaaaa taaatctctg
    10321 cctaaaacag tagctattgt aactccaaaa gctgaaacca tcttaactga tgcaaatatt
    10381 gcataaggta taaaatttcc acttgctatt gctcctattg caaatgtata ggctgcttta
    10441 tttattggtc cacctaagtc aaatgaaacc atagctccta ttattgcacc tagtagtatt
    10501 gcatttactc cagtcatccc atttaaccaa tttataagac cattgttaag tgctgctaca
    10561 ggctttccta ctacaaataa catcaataaa cctactacca aagaaccaac tactggatat
    10621 acccaaaaac ttacgaatcc agctaatgtg cctttggctg gtatattctt ctttaaaaat
    10681 tttactatat aaccagcaag taaacctcct aacatacctc caagaaatcc actacctatt
    10741 aaatcagctg ctagacctgc tgcaaatcct ggtccaagac ctggtttttc agctagtgag
    10801 taagacatat atgctgataa tactggaacc atcaatgtac ctaacatacc tccagaaagc
    10861 tttcttaatt gccataacca agaaccttct tgattgtata gttcttgtag accaaatgct
    10921 tgagatgcta atactgcaaa tgcaagtatc atacctcctg ccacaataag tggtattata
    10981 tgagatactc ctgtaagtat tgctgatttt acatcttttt tccatgatga tttttcacaa
    11041 tatgatatat cagatgattt ttctatataa tcacctttac cttgtttttg tgctacttct
    11101 aaagcttcgt atattatttc ttttgctctt tttagtggag ctgctactga cgtttttatg
    11161 tttggcaaat gttcaaatct ttctgtattt ttaggtgcta catctgttgc atatattatt
    11221 gcatctgccc tttttattat atctggtgta tgagggtcca ccataccatt agctccttgc
    11281 ttttctacat acacatccac accgatttct ttaccagctt taattaatgc ttctgctgac
    11341 atatatgtat gtgctatacc tgcagggcat gctgttattg ctaatataat tttttttgat
    11401 tcattttgaa tcctaatctc ttcttttatt tgttctttct tttcttttat atctaagtta
    11461 ttaaataact ctttcttagt ttttgaattt aacaacatat tcatataatc ttcatttgac
    11521 agtctagtaa ctaactcaga aagtatttgt atgtgtgtat ttccaccttc attttctggt
    11581 actgctatta aaaatattat ctctacttta ttatttgggt ctacgctttc ccaattttct
    11641 attggtgtct ctaaggtcat agctgcaaat gcagcttctt taactgactt agattttcca
    11701 tgaggaattg caagccctct ttcaaaacct gttggagata aagtttctct gtacattaca
    11761 gcttctaaat attcctcata agatgttaac ttgccttcat catatagctt tcttgctaag
    11821 aactttattg cgtctttctt tgtttttatt ttttgtttta aaaaaacaag gttttcattt
    11881 gtgattttct taaattccaa aattacgccc tccttaaatc atttaatgct atgaatatag
    11941 cataaaataa attatgaaaa tgtttttttg aaattataca cacaatttct tcttaaaaaa
    12001 taaagatttg tgtatttata cacaaatctc tatcttaacc agtattgctc tattattgct
    12061 ctcataatca tcataattgg aaccttatct gatatattgt acccatttac ttgtttaatt
    12121 gttgaatagc aatataaact tatatctgca atttgttgca attgattttc acatatatgt
    12181 gttagagcta ctaccttaca acccttatta actgctgtct ttgctacttc tataacttct
    12241 ttcgtttctc cacttaaact aagtgcaaaa aacatatctt gttcacctaa ttttcctata
    12301 tcatgaagta cttcatgtct ttgactatag taagttatat tatcatgccc acctctaatt
    12361 tcttttacta atatctcaca taaaggaatg ttttgaccta ttccataaac tataatactc
    12421 ctagattttt gaattatatc tgctacttta tttatttttt cataatctat tagctctaat
    12481 gtctttttta tatctgattc aaaaccattt tttggctctt tatcctcatt ttttaactct
    12541 tcttttaaat tattttttag ttgagagaaa ccatcatact ccattttttt acatagccta
    12601 actatggtat ttgggacagt aaaaaattta tctgctaaag attgtattga taattttact
    12661 atttcttctt tgttttttct catatattca attatcatgt cttctgtatc tgtaaattta
    12721 tactcatatt tttttgctct ttcataaaat tccatagttt ctcctccatc tattttatta
    12781 ttcataagta aaattcaaaa atattagcta aaattttcgt taatataatt ataatttaat
    12841 atttttaatt tattaatgca tactactctt tttattatac ataaaaaatg tgtacttcct
    12901 atattgatag agatgattca agtttttatt ttgatacatc tctatcaata tttttttaga
    12961 aaatacacat ttttttcaaa tacttatttt taattaaaac tttaggtaat ctattcttta
    13021 tatataatta ttagacttga aaatatcttt aaaatcaacc aattcaatat tatttctttt
    13081 taaccacatt ttaacttcct tatcacatag cattgcatgt tcatatactc tctcttgaat
    13141 aagagaagat gattttataa gactataatc tataaatcct ggatgagtaa ccatcaatgt
    13201 tatatcttta tctaaattta tatatttttc ttcaaataat ttaacaaaag atttatttaa
    13261 cttgtaaaaa tcattctgag gatatttact tggcatgcta atacatgaat ccaaataata
    13321 gggacaactt ggtataccgt attcttttgc agcatcacac attgctgata ttgatacatc
    13381 ttcttctata ccatgtatat caatatactc aggcaattta ctcatataca acttgtaagt
    13441 ttcaatttga gcacaaactt cttcatatac ttcttcataa ttaaaaacct ctttacctgt
    13501 cagtagttgc gttcttctta ttttgctaga aacaaatttt ccaccttcat ctaacaaatt
    13561 ctttatctta atatgttctt tgcaacaagg ttctcctatt actaaattaa catgtaaacc
    13621 aaaacataca tcatcatttt ttaccatttc tatagcttgt cttgaaaaag gcatattcac
    13681 catgattcca gcacttgtaa caataccgtt cttataagaa gatattatcc ctagtgtaac
    13741 accttctgaa tatcctatat catctgccct aactactagt ttcttcattt tatgcgtctg
    13801 cctgctttct caactcatca agttgcattt ccatctcatc ctttacttta acaacatccg
    13861 ttcctatgat gatttgaact gatgtattac tcaatttaat tacccctttg gctcctgttt
    13921 ttttaatatt atcatcattc aaaatagtag catccttcac ttctaaacgt aatctcgtca
    13981 tacaattatt aagagtcact atattttcat aaccaccaca atttttaatt atctgtttag
    14041 ccatatatga aaaattacca tgagaaagtt ttaaattctt ttctttttca ctaactttat
    14101 cacctatctc tatctcaact tcacgtcctg gtgtttgcac attatctttt attattatat
    14161 atttaaatgt tacataatat aatacaaaga atacaactcc tacaggtata actaaccacg
    14221 ctttatctcc ataactaaaa cttaagacat agtcaattat acttgctcca ttaaatgaac
    14281 ccaagcgaac acccagtaaa tatagtacaa ctccacctag accagaataa aaagaatgaa
    14341 ttatatataa ctttggagat gcaaataaaa acgaaaattc tattggttca gttactgttg
    14401 ccataaaaga agtcaatgct ccagcggtca ttgcaccttt tacttcttgc ttctttttat
    14461 cttgtgctgt tttatatata gcataagaaa tagcaggtat tgaaaacatc ataattatgt
    14521 aaaatcctgt ccagaagaat cctgcatttg ggtctcctgc cataaatcta ggaatttctc
    14581 ctcttataac ttctcctgtt gatgttgtat attcacccat ttcaaataat atgtaagcat
    14641 ttaaaacttg atgtaaccca gttggtatta gtgcacggtt acagaataaa aacaagaata
    14701 ttcctattgc accagctcct cccaaccaaa aaccaaattg attcattgca gcttgtggat
    14761 atatccataa taaactaaat atatatgata aaattaaagc aaccactggt gatagtgtaa
    14821 ttacacattt ttctcctgca aagaagctta aaaatgctgg aactttaact ttatatgttt
    14881 tattgtaagt ccatgctata caagctccaa caattatccc accaaataca cctgcattta
    14941 atgtatcatt caataactct aaatttgact taaatatcat atatgcaact acggctgcaa
    15001 ccattacact tgtcttgtct ttagactttg agtaggcact agctgctcct aataaaaata
    15061 agtagtccac atttgaaaat actatattag atatattaga tatagctggc acattgagca
    15121 tatttggacc aaataataat cctaatatac ctgctgctgg cattacagct attggcacta
    15181 gcatagtctt tcctaaaagt gacagttgtt gcatcatttt gtttaagaac ctcttcatat
    15241 ccaatcccct ttctatttcg gtttaatttt ttgtgaaaac gatttattca cattttatat
    15301 tttaaatatt atatttgttt aaacaaattg tcaatatttt ttattcattt tatttttatc
    15361 atttagttta acatataaat ccttttaagt gtattgctat atctagtcta tttttttaat
    15421 tcattttttt tattttaaaa atatgtttaa ccatgtattt gaaacaaccc acaaaataat
    15481 tctattttgt cctttttatg gttgatatga ttctattttc actatacatg tctaaacaca
    15541 tttgatataa tttgttcata tcagttcaat aatattacta aagaccttta aggagggata
    15601 ggggtatatg gctaaaaata aattttcaga gatatatgaa gtattgaaag aggaaatact
    15661 tgatggtaaa tatacaagta atatgatgct gcctactgaa cttcaactta ttgaaaggtt
    15721 ttcatgtagc agaaacactg tacgtagagc aatttctcaa ttaaacacag aaggatatgt
    15781 tcaaagtata aaaggcaagg gtgttgtagt gttagaaaat agttgttcta atgatttttt
    15841 tctaaatatg cacaatttca aaggtgtaga atcgattgta gaagataaaa aggttaatac
    15901 tgctactagt gttctccact tcagcaaaat cttaattgat aataagttat ctaaaaagac
    15961 aggttttaaa gttggtagtg aagtatatta ccttcacaga ctaagatata ttgataacat
    16021 acctaaaatt ctcgacatta actattttct atgtagtata gttaaagacc ttgatgtttc
    16081 tatagcacaa ggctctattt ataaatatat agaagagtgt ctaggtacaa aaattgtttc
    16141 atccagaaag atatttaaaa ttgaaaaagc tacagagctt gagttaaaaa cgctacctct
    16201 aaatgattat aattgtgttg gtgttattaa aaatagtgta tatactgatg atggaaagct
    16261 ttttgaatat actgaatcaa agcatacacc tgaaacattt gtattcatgg atgttactca
    16321 aagatattaa aaaaattatg tttaattaaa cataattttt ttacgtttag acactttatc
    16381 ccatactaac ctcactattc tatatacaat tatgtgttta tacaaataat tatttattgt
    16441 atattttagc tttaatatta gtttaatgct tgacaatttg tttaaacata ttataattaa
    16501 cttataaatt acaggaggta tcaattatga aaaattggtg gaaaaaagca actgtctatc
    16561 aaatatatcc aaaaagtttc aaagatagca acaatgatgg tataggtgat ataaatggta
    16621 ttatagaaaa attagattat ctgtattatt taggtgttga tttattatgg ttgactccta
    16681 tgtacgtttc tcctcaaaga gataatggat atgatataga agattattat aatatagacc
    16741 caaaatatgg gacaatgagt gactttgaaa aactcttaaa agaagctcat aaaagagaca
    16801 taaaaataat gatggatatg gtcctaaacc atacatctac tgaacataaa tggtttaaag
    16861 aatctaaaaa aagcaaagac aatccatatc gtgattatta tttctggaaa gatgctaaac
    16921 ctgatggttc tgttcctaat aactggatat ccagatttag tggaactgct tggaaatatg
    16981 atgaaaccac taaccaatat tatttacatt tatttgaaga aactcaagct gatttaaatt
    17041 gggaaaatga aaaggttcgt gaagaatgtt acaaaatact agaattttgg gctgataaag
    17101 gtattgatgg ttttcgttta gatgtagtca acctactctc caaaacacct ggattacctg
    17161 atgaccctat aacaggacca aaaggagatg gaagaactca ctacgctgat ggtcctcgta
    17221 tacacgaata tttacataat atgaatcaaa aagttttcaa acctaaaaat atagttactg
    17281 taggtgaaat gtcatctact acacctgaag agtgtatcaa ctatactaga gaaaatcgag
    17341 aagaactatc tatggttttt agcttccatc atatgaaaac agattataaa ggaggcgcaa
    17401 aatggactaa tgaaatgttc tctctggata aattaaaaaa agcacaatct gactttcaat
    17461 ataaaatgta tgaaggaaaa ggatggaatg ctctatttta ctctaatcac gaccaaccta
    17521 gagctttatc tagatttgga gatgatagat tttttcgtca agaaagtgct aagatgttag
    17581 ccataacact atttggtcta caaggtacta catacatata tcaaggtgaa gaaataggta
    17641 tgacaaatgc ctactttact aaaatagatg aatatgatga tgctgaaagt aagaatgcat
    17701 actatcatat gattaaatct ggtattgatg aaaaggaggc attgcttata cttcaacaaa
    17761 aatccagaga taatgcccgt actcctatgc aatgggataa tactatttat aaggggtttt
    17821 ctaatcataa accgtggtta aaagttaata atgacaatat tagtgtagaa aatgagctta
    17881 atgattctcg ttcagtattt tatacttatc aaagattaat caaatatcgt aaacaatatg
    17941 atatttttac agaaggtact tatagattgt tagatgaaaa tcataaaaat ctatttgttt
    18001 atgaaagaga gtataaaaac caaaatcttc ttgttataag taatttcact catgataatg
    18061 tagtatataa attacctgaa acttatttga ataaattaaa ctacacaata cttgaaacca
    18121 attacactag agatataatt gaaaataaaa tggaaataaa accttacgaa agtataatga
    18181 tatattataa ataaagttat ttatgtaaaa ataggtataa caccctggtg ttataccaat
    18241 tttactaaat tcaaagtaat gtttatagaa tatctataga ttacaataat tatttgactt
    18301 ctacatcatt atatttcttt gaatatactt tagtcatata gaaatatata ggaactacaa
    18361 ttatcatccc acctaatccc caaactatct tcataggttc atcaatacct gcttttatca
    18421 gtaataatat acttataata actgcaaata ttggtataat tgctcctcca ggtattctaa
    18481 aatttacatc tttaccagca tacttctttc tcaatattag tacagctaaa catgtaggaa
    18541 tatattgaat aaatctagat acaacactta tttgagataa tgttgtgaat gaacccgacc
    18601 atgctattag taaagttcct atgacagata ctataattgc tatataagga gctccatttt
    18661 tattagtttg tcttatagac ttaggcatta atccttgttc aaccaaagca gcagcagacc
    18721 ttggtgtaaa tatggatgat gcaatattta tacctccaac agatactata gttcctattg
    18781 taattatata cccacctata ggacctaaca tcttaatggc agcatctgca acaggagtag
    18841 ctgaccctgc taagccatta cccaacaccc ctatacttat tcccagtata agcatatata
    18901 ttactgatac tacaaacatt accattacca atgctttagg tacatttttc ttagggttct
    18961 ccatatcttt tgctgcaaca gctaaagatt caaatcctgt aaaagcataa aataaagtta
    19021 tagatactgc tacaaaagct gatgacgcac tttgaccttt ttgtattatt acaaatgggg
    19081 taaaattaga accctttata aagaataatc ctacagctat aaataaaact attggtaata
    19141 attttcctat agtcatgata ttatttaagt gcttagattg tttcattccc ataaaattta
    19201 taatcccaag ccctacaact aatataccaa ttattatatt tttaataagt ggttctgctg
    19261 cttgtggcca tacagatgat agtgttacag caaagaaatt tgccatagta gcccaagcaa
    19321 tcatactaac tatccacttc ataaatccaa cttcaaatcc aacaaaatct ccaaatgcct
    19381 cttttgcata aagatagggc cctccatcag tatcaaacca actacctgct tcagcaaaac
    19441 ataaagcaat agaaacagct aaaagcatac aaaaaactaa tactaatata cttgctggac
    19501 ctatatctgt ataagcatca ccaggtaacc cgaatatacc tgaccctatt attgcattga
    19561 ttcctaatag tacaatactc caaaaaccta acttaatgcc tttttccatt gttattcccc
    19621 ccaaagccaa cttaatatat ttgtattttt tatttagatg cttctttaac tattgccata
    19681 aatatttttt tcatattatc ataatctcta gtcatcattt ctggatgcca ttgtatccct
    19741 attacaaact cacttccttc cttttctata gcttcaatta aaccgtcttt agatgtagct
    19801 gaaacaatat atcccggtgc tactttgttg acaactaagt gatgaaaact attaactaaa
    19861 acttcttttt ctcctagtat ttcatataat tttgtcccct cctttatctg tactgtatgt
    19921 gtaggtacat tagatagatg ttgctgattg tgtttaatat aagcaccttc aattaaagat
    19981 aaatcttgat acaaactacc tccttcagtt acatttataa tttgttctcc tctacatata
    20041 cctaaaactg gttttttcat atctaaagca tgttttaata atttcatatc aaaactatct
    20101 ctctttggtg atattgcccc caacttatta tgaggttctt ctttccatat gagtggattt
    20161 acatcttgtc ccccagatag tataagcgca tctatattag atacctgctc ctttataatc
    20221 tcatcatcat atacaatcgg tacaatatat ggtatagctt tacacataac tactgattgt
    20281 atataatcat tatttacata agccctttca tagccaggaa acattcctcc ttcatcaatt
    20341 agtaaattac ctgatattcc tattattgga tatttctttt tagccaattt cttcacccct
    20401 taacttattt gtgaacaata aaaaatgcta cttctcttaa agagcaagta gcataccaag
    20461 attttattta tttgaacatt ataatttatt ttagaaatac tttttttgaa tacgagtaat
    20521 ataaataact ttatttactt atattttatt ttaatcctgt ttagtttgac ttttttaaat
    20581 tgttttaagt acaactaata ggtaaaatag gcatttagat tttccttttt atcaacctat
    20641 taaatactgt ttaatatatt ttttcccctt ctatttaatt cacttccctt tctaccagat
    20701 tcacatatta tcaaatccag ctcttttaac atattaagta ttcctcttac ctcaccttct
    20761 gttatattgt agcctaattc atttattgaa ttaacaatac catttctacc tatattttta
    20821 ttaagattat tggcattttt taaacactcc attactaact ttactttctc tatagatgtt
    20881 ctatccttta atatgcttat ttctttacta aaatcttcag ttatatttaa taagttatga
    20941 ggtaaatcat ttattaaaat aacatcctca gaactcataa tgttaatata catagcagta
    21001 ttttttaatt ctcttatatt acctggccat tcatatgcat taataatgtc ttgaacatct
    21061 tgactaattg ctctcttcct tttcataaaa tgctttaaca taacttctat atcttctttt
    21121 cgctctctta aaggtggtat atttatgggc aatacattta tcctatagta taaatctgct
    21181 ctaaatctat ctccttttat catttctaat aaatttttat ttgtagccgc aattactcta
    21241 acatctatat ctattacatt ttctcctcca accctcatta cttgattctc ttgtaatact
    21301 ctaagtaatt tgctttgtaa gtatataggc atgtctccta tttcatccaa aaatatagtt
    21361 ccattgttag cctgttcaaa taatcctttt ttacctcctt ttaaagctcc tgtaaaagca
    21421 ccttcttcat atccaaaaag ttcactttca agtaaatttt ctggcatagc tgcacagttt
    21481 attgctataa atggctgact atgtcttggt gatgcattat gaatagactg agccatgagt
    21541 tcttttcctg ttccactttc tcccgttata agaattgtat aatcagattc agctattttc
    21601 atacctaatt tcttagttct ttccatcttc gttgaaactg tttttatatc atcaaaagta
    21661 tatctagcaa cttgtccctt ttctctaagc ttctttgata ggttttgctc caattttctt
    21721 atgtaagtta tttcttgaat acaaaaataa tatccagtaa cccttccaaa actctctata
    21781 ttatacttat ttacgtttaa gtacttatta ttaaatttta taacttcatc atgtgcctta
    21841 ctcaaactaa aaatcttttt aatattctca ttctctaatt catctatatt tttccctata
    21901 atattacttt gaatatctag tatatccctt aaactattat tacaaataat tatgtttccc
    21961 ttatctgata ccattgccat acctaagttt gataaattta ttatggaatt tagttcatct
    22021 gcttttatag taagttcttt gtatttagta tttattcctg aatataaact aattatttca
    22081 tctgtatact taattagcct ctcagtaatt tctttatcat ccagtttgag ttttgctatt
    22141 atttgaataa acgttgaact atcaatatac ctatggccta aatcaataac ttcttctata
    22201 tattttggaa ctaaacttga ctctcctggc gttatagcta tcttaatatt tctatattct
    22261 tcattgggat tgtatggtat aaaattcaaa tgatttattc ctatattgta taaattagat
    22321 attgtttcca atacagtatg cttattatcg tttactacta atacatctat tccttctggc
    22381 aatgaaaata acttatatat atccttttgc tttatgctcc tatttatagt tattatcttt
    22441 gagacatctt ccacatattt ttttattttt aatactctat catctatcat taccaatatt
    22501 atgtcatctt ttattaattc cttctctgtt attttattta aataataatt ttttatcatt
    22561 actttatctt taaagatcat ttctagattt ttatttaaga aacattctaa tttagacaac
    22621 ccatcagtta ctactgctat tgttttcatt tgattactcc ttttaaaata tactctactc
    22681 ttttataata tacatttgat tttcacttta ataacacaaa aaattgtaca tttagtatac
    22741 taacatattc ctttattagt tttatgtcca taaatatcat agttgcaata tctatcatat
    22801 ttcttaaact tctataaagc aaaaattgtg ccaaattaat aattttctta attttattct
    22861 aaagttcctc aatagtattt acagacttag cacttatagc ttataagtct ttatattatt
    22921 aatctatttt tataggttaa ttgtacaaat catatatcac ttttacctat taaatgcatt
    22981 ataaaaaatt gtatttataa acactattta ctactcttct aagtacaaac agtatctaca
    23041 tactataacc tttcaccatt agattctatt acttgtttat accagtcaaa actctttttc
    23101 ttaatcctag acaagtctcc acttccatca tcatacttat ccacgtatat aaacccatat
    23161 ctcttggcca tctcaccagt agatgcactt actaaatcta tacatcccca tggagtatat
    23221 ccaaataaat caacgccatc ttctacagct tccttcattt gctctatatg tgcttttaaa
    23281 tactctatac gatagtcatc atttatcact ccattagatt cttttttatc ataagctcct
    23341 aaaccatttt caactaccat cataggtatt ctatatctat cataaatttc atttagtgca
    23401 tatctaagcc cttcagggtc tatttgccat ccccattcac tagacttaag atatggattt
    23461 ttcactccac ctaatatgtt gccacttgta ttatcttctt tagaatcact acttacacat
    23521 gtagacatat aataactaaa tgtataaaaa tctacacaac cttcttttaa aatttctaaa
    23581 tctccttttt ccatttttat ttcaatatta ttttctccaa aatatctatt catataagtt
    23641 ggatattcgc cacgcacttg tacatctcca cagaaataat tcattactct actatctctt
    23701 tgagttttaa ctgcatcatc tggattacaa gtataaggat acattgttgc aaatatttgc
    23761 atacatccaa cttgataatt tgaatctatt tcatgagcta acttaacagc cttagcactt
    23821 gctacaaatt gatgatgtaa cccttgaaaa cgaagttgag gtatatctac ttggtttata
    23881 aaatctgtag tcccttcatt taatattcct tgtgataagt agcctcccat aggcattgta
    23941 gctgaattta tttcattaaa tgtcagccaa tattttactt ttcctttata tcttttaaat
    24001 attgtttcac agtaattcat atacaagtct attacatctc ttgaaaccca tccattgtat
    24061 ttctctgtta ttgcaaatgg tatttcatag tgagatattg ttattaatgg ttctatatta
    24121 tattttaaac attcatctat cacattttca taaaatttaa gtcctgcttc atttggttct
    24181 ttctccattc cagttggaaa tattctagtc catgctattg aaaatctaaa taccttaaat
    24241 cccatttctg caaataaagc tatatcttct ttgtatctgt gataaaaatc tattgcttca
    24301 tgacttggat aaaatgttcc tttttctata actctcgtta ttcttttact tactttttga
    24361 gaacctccag tacacatatc tgaacaagaa ggacctttcc catctaaatt ccatgctcct
    24421 tcacattgat ttgctgctgt tgctccaccc cataaaaaat cttttctaag tgccataatt
    24481 ctacctccaa taatttattt atagtaactt tattttaaaa taaaaataca tatatataat
    24541 tcttaattaa tagaactctc ttttacgcta aaacagttat caatttctga ctattattta
    24601 catgcttttg tgtattttct acaatatcca cataatcaga ataattagta acaactactg
    24661 gtgtttctaa gcaatatcct tcttttgaaa tactttctat gtcaaaagtt attaatgtct
    24721 gacctttttt aatcttatcc ccttgattaa caaaagattt gaaatattta ccttccaact
    24781 gaatagtatt taaccctata tgtatcaata gttcacaacc attatcagat ataattccta
    24841 ttgcatgttt tgttggaaat aaagtcatta cagtcccatc aaatggtgcc actacttttc
    24901 cttctttagg tgttattgct acaccttttc ccaatatacc tgttgaaaac gctgcatctt
    24961 gtatctgctc caaagccttt acttcacctt ttattgggct atatactact tctcttttgt
    25021 ttttttctat aacgccttgc ccattatcat ctttagaaat ttctactata gcatcatctt
    25081 tccaaaaaaa taatgttaaa acaaatccta ctacaatagc tactattatt gctattatag
    25141 ttgcataaac acctttcata tctccagttg ttggatttat ataattaggt ataccaaata
    25201 ttccaagtcc acccattaca taacttttta cattcattat ccccattaca gctcctgcca
    25261 cagcaccacc tacacaacta tatatgaatg gtgtttttct tggtaaagtt attccatata
    25321 ttgcaggctc tgttacacca catatccctg aaataactgc aggtatacac agctctttta
    25381 tcttcttatc ttttaattta aagtacattg ctgctactac tgctgtttgt gcaaaagatg
    25441 gtacaaatac tcccactaat attgtgtcaa accccatagt cataaggttt gacatagcta
    25501 ttggtactaa tccccaatgt agaccaaata ttacaagcac ttgccacaat aaaccagtta
    25561 atgcaccaca taaaattggt gaaaagttaa ataaagctaa aaatccattt ccaactatat
    25621 tagaagcata ggtagctata ggccctataa ccataaatcc caatggtaaa gaaactaata
    25681 aaactgccat tggtacaaag aaattcttta ctacatctgg tattatttta gcaaacactt
    25741 tctccaactt agctgctaat aatactatta aaattactgg tactactgtt gaagtgtagt
    25801 tcattgctat tactggtaat cctaagaaag ttatatatac tggtgattca aatattgttc
    25861 cagtaaatag attgtataaa ggttgacctg tagatgctag agtatctaat tgaatacctg
    25921 aatagcataa aactgcacct ataagcattc caataaatgg ttttaatttg aatttcttag
    25981 cagctgtata tccaagaatt attggcatat actggaacat tgcatctcca attgcattta
    26041 acataatata tgcaccatca gtttctccat acaaacccaa tgctgtaaat actgcattaa
    26101 atccttttat cataccagca gcacacagaa ctcctaatat tggttgaaaa actcctgata
    26161 ttatgtctat aaacttatta agtaatcctt ttggcgcatc tgagtctgaa ttatctattg
    26221 tatctcctcc taatccagcc aaatcgcaca caacttcata aacatctgga acatgattac
    26281 caataactac ttggtattga cctgcacttt tcattacagt aactatacca tccatttttt
    26341 ttagcacatc atcatttgct attgactcat cttttaattt aaaacgtagc ctcgttatac
    26401 agtgagataa actgctaata ttatcctttc ctcctacatt cgcaatgatt tcttttgata
    26461 gttgttcata ctttctcatt ttttctcctc cattttcttt ttgaaatatg aaggtttggc
    26521 caacttaatg tcaccaccca atatatataa acctaattat taggatttat atccgactta
    26581 atacttttac ttaccactct ttcaacgtga atagttaagt ataatttttc ctcatctgtt
    26641 aaatcgtagt tgtatttttt atgtataaat tcatccaact tttctatgaa tttataagca
    26701 tttttatatt taacttttat tacatttaat aaatcatctt cattattttc atgtaaatta
    26761 ttactaacaa ttcgttctgc aaaatacttt aagtgagtaa taaatctatg ataataaact
    26821 gaatcttcat caaatactat tctgtaatgg tatttaacca tatttgaaat ttcttgtatt
    26881 atttgtgtaa tctcatatat agtttttata ctttgatcca tttgtgcatt aactatatgc
    26941 agtgctataa atccagcttc atcttctgat agtctaattt caaatttttt ttctatataa
    27001 tccaatgcct ctaaccctat tttaaattca ctcttataaa atctttttat atcccaaagt
    27061 aatacatttt ttacacttac tccttcacga gctctttcta ttgcagtata catatggtct
    27121 gttaaagaaa tataaatact atcatttaat cttttcccta gtttttcttt agcatataaa
    27181 attatttcat ctgataattc catatatctt ataggaatat ctgctattag ttctttaaat
    27241 ttatcagata tatttgggtc tgaaagtttg aatatcttat caattttatc ctttgatata
    27301 tgctctcctg tacgtttttt ataagctaaa cctctcccca taactactat ttccttatga
    27361 ttttcatcag ttgtaataat tacattatta ttgagtattt tttcaataat cattgtgatg
    27421 ccccctttat tagcattaag ttaaaataaa tcttttttaa ttatttagaa tatttaaaat
    27481 gtaatttatt acataaaaaa aaacctattt attacacatt aaatagactc ccatgagtcc
    27541 tgagtaataa ataggtttag cttgtattta aacaatcact atccgtttgt attttatttt
    27601 aattattatt tattatatgt tagcaaattt attttttagt gtcaactttt tctcaatatt
    27661 ttaattttaa ataaattata taaattgaat cttcaaagta ctatttttat caataaacaa
    27721 aataaaaaag gtattacttt ctttaagtaa tacccattta tttctaattt aagtggtttt
    27781 tcttaatctc atcaagtagt ccatcttcta aataaatttc taatgcacat cctaccattg
    27841 cctttactgc tttgtgaagt ttatcataag cttcctcaga atttgcataa tttagaaatt
    27901 ctttttcatg aacatatacc attggactta tatctaaggc tatttctgta tacatagtag
    27961 ggcaaacttg acttacatta cctatatctg tagaacctac tggaccatct ttaccttcta
    28021 atatatctgt tatacctgcc tcaatcaaat tattctttgt tatcttttga agtactttgt
    28081 tatttattat gttgtcaaaa gaattttcaa agtatctata agaaagctta gctcctgtca
    28141 ttaactctgc accttttgca cagtttataa cttttttagt tacttcatct aaataacttc
    28201 tttcagcagc tcttacgaaa aacttacaag ctgctttttc tggaactata tttggagcct
    28261 ctcctccatt tgaaactata ccatgtattc taacatctga ttttacatgt tgtcttagtg
    28321 catttatccc agcaaaagta agttgtactg catctagtgc attgactccc atatgagggt
    28381 gactagctgc atgtgctgat accccttcaa aactaaactc taatgaatct atcgccaaag
    28441 ccttacagtt tatattatta aaagcttcta tatgcatttg ataacttaca tcaacatcat
    28501 caaaagctcc tgccttaact aaatcacatt ttcctcctgt tgtttcttca gctggtgttc
    28561 ctattagtac aatttttcct ttaaaatttt cttttaactt acttaatact atacaagctc
    28621 ctagtgtaga tgctgcaatc cagttatgtc cacaagcatg agctggttct ttattttctc
    28681 catatccagg aagtgcatca tactcagcta aaaatgctat ggtaggtcca tcattatctc
    28741 ctaattcagc tctaaaagca gtctccatat tacaatatgg ataaactgta tcaaatccat
    28801 attccttcat tttttctact aagtattttg atgatatgta ttcttcttcc cctaattcag
    28861 gattgttaaa tataaaatta caaacttctt caatttcttt tccaagttca ttctctatct
    28921 cataagctct cttctttata ctctctatca taatttacct cctactagaa tcctagatat
    28981 aatcctattg tcaaaaatgc cattacaaga attgttaata ctaccattaa aggaattacg
    29041 aatctaaccc actttgacca aggaatattg gctactgcta gtgctcccat taaaacacct
    29101 gatgtaggtg ttatcaagtt agttacacct ataccaaatt gataagctgt aactatcatt
    29161 tgtcttgata catctactaa gtcgccaagt ggtgcaagta caggtattgt aagtgatgca
    29221 agccctgatg ctgatggtat taaaaatgct attaatcctt ctattaagaa agttaaattt
    29281 ataaatatag tttttggtaa tccatttaat aaatttgctg cagaatttaa aattgtatct
    29341 attataaatc cattttctgc tattattaca attccacgtg caaatgctat acacaatcct
    29401 gctgtcatta aatctcctgc tccacttata aatgaattaa ctatatcatc ttgtttaaga
    29461 cctgatgcta tacctgatat tatacctata gctgtaaata tcattgcaat ttcagttata
    29521 taccatccca actttaaaac tccatatatc ataatcgcca tacctattgt gaaaattgct
    29581 attaccatgg cttctctttt tgtaaattcc tttatatttg tatcactatt aaccattgat
    29641 tcttgattta gtgatatatc gtgtactaaa gattttttag ggtctttttt aactttattg
    29701 gcatacatca taacaaatcc tatagatata gccatatata ttataaacat aacaactcta
    29761 aactctattc cagaacctgg tgctatttgt gataatgctt gtgctattcc tacagagaaa
    29821 ggattcgtag tagctgctcc aaatccagct gttgctccta taaatactgt ggccactgct
    29881 gtcaatgaat catatcccat actggtcata agtggaataa atatcatata aaaaggtagt
    29941 gtctcttcac tcattccaaa cgtcgtccca cctagtccaa atagaatcat tgaaatcggt
    30001 attattaaaa attgaaactt cttcatttta tttacagtat gagctataac agcttctata
    30061 gctcctgttt tattaactat cccaaaagct cctccaacta ttaaaacaaa tccaactact
    30121 tcagcagcat ctataaaccc gtttataggt gctgtaaata catcagtaat tccttgtgga
    30181 tttgatggtg ctttttcata agttccagct acaacaactg accttccgtc tatatctact
    30241 ctttcaaaat ttccacttgg cactatccaa gtaagaattg ccattaacac tattagcaaa
    30301 aatattattg taagtgtctg tggcatagta aactttttct tttttaaact gctcattttt
    30361 aatctcccca ctttttaaat taaatatttt attattgcat ccctttatcc tattttgtat
    30421 agatgtaaaa aagctcaaca tggatacatg ttgagctaaa tgtgctaaat acaacatacc
    30481 tgcatcttcc ctttatcttg tttaagatag ctctccatca aaattcggga taattttgat
    30541 gacagtactg tacctattaa atacagtccc agcactagct tcggacacta gcacttcggc
    30601 acttactcct tttatattgc ctcattggtt tccaacctct tcaatattaa tcttagtaaa
    30661 tgcaacctct acctcaatct gtttgttaga tgaggtaatt cttattaatt tttattaatt
    30721 caaagtaatt gtagcataat atgtcgagat tgtaaatatt ttcagtataa taattcttac
    30781 tttatgattt cattccattt ttcacaaata attttttctc catataattt aaatactgta
    30841 gtatatttta aatacacaca aactttccac aaattttaaa ttattataat acctttataa
    30901 taaaaaataa aagctatgta aacttatcaa tttacacagc tttatataca ttaatctact
    30961 ccaagtacag ctttaagctt tgatgctatt gtaataactc gtggaccaaa tataacttga
    31021 actgagtttt tctttttaac aactccactt gcacccaatt catttaccca gaagccatct
    31081 tcatagaatc catcaattga atttagctct accctaagtc tagttgcaca gtttgtaaca
    31141 ttttttatat tattacttcc tcctaaacct tctattatag aatgtacaag ctttgtatct
    31201 ttatcatcta cttcctcttc tactgcattg ttgtatgctg ttttaccagc atctacagat
    31261 tgtctttctc tatattcttt cttactataa agcttaactt cttctgaact tcttcctggt
    31321 gtttttatat caaacttctt gattgcccat gtaaatatta tataagtaac tataaaaaat
    31381 attggtatca aaaataataa tggtaacgca tccacttttt gtggttgtaa taaattagga
    31441 aacatatttc taaatgattc tcccattata gaaacattaa acatttctgt aaatacatac
    31501 gtcaatcctg ccagtggtac atatgctaca aaatacaata atggtgcaac aaataggaat
    31561 gtatactcta ttggttccgt tacccctacc aacatggctg ttactattgc tggtatcaat
    31621 atacttattg cttttttctt attagcatta tcagccaact tatacatagc taaagctgct
    31681 gctggtaata ttgcaaaatg tattaataaa cgacctgttg tgaagttacg agttatataa
    31741 gatagtgtat ctgggtctcc catttgagct aatcttatat tattaacacc ctcgtaaatt
    31801 gctccaccta cttccattgt tccacctact cttgtatatt ctatagggaa tgcaattaag
    31861 tgatgtatac caaatggtaa taatgcttta tccattgctc caaaagtaaa tgttcctaat
    31921 aatccactag aacctatcca attaccaagt ttagataatg ccaaccctac tggtggccat
    31981 ataaagtaca ttgctgtacc caatactatt gatgctataa acatcataat cattgaaaat
    32041 cttggacctg agaaaaaaga taatgcacta ggaagttcta tgtcaacaaa tttgttatgt
    32101 actgcactag ctacaaatcc agctattata gctccaaata tactacaatc atatgaaaag
    32161 attcctaaga aagaaccata taaagaactt cgactatatg cttctgcctc tcctaatcca
    32221 gatgccataa acgcttctgc tgtaactgta tctgaattta taccatttgc tgctaacaat
    32281 gtacttataa ctgtgtgcat tcctataaat aaaacaattc ctcctaatgc accccatcct
    32341 ttttcctttt tagataatcc aaaggctata cctgtaacaa agaatattgg taagtatctc
    32401 attaccataa atcctaaatc gtttattact ttaaagaata catttataaa tgacccttct
    32461 tttattagtc cgctaagccc taatgcagaa acgttttcca tatttgcaaa agctgaccct
    32521 agtcctataa atactcctgc tacaacaagt aatataacag gtatcatcat tgctccagaa
    32581 agtacttgta atttatcctt catagtatta tttcctccat ttttattgaa atgccaggct
    32641 atataatgca tatatatata cttctattgc tttgtataat gtatctatac ttatattttc
    32701 atttgcctga tgtgaatttg gattatcccc ctctattgtg ggtccaaatg caactccatt
    32761 ttttaacact cttgcataag atgcagctcc ttttgtaaaa agttcggctt cttttccaaa
    32821 accttgttta tatgcatttg ataatttatt tattaattca ctatctggtt ttacatacag
    32881 taattttaaa tccttatata tatcaactat taaattttct ttttttccaa tttcattaat
    32941 tctattagtt ataaactccc aacttatacc cttaggatat ctaaagtcta ttttcatatt
    33001 caattcattt ttctctaaga agatactcat tatacatatt gtagaaactc ccatatctac
    33061 atcttcttta tatatcccta atttttttcc atgattatca tctgtaaagt atgaatttaa
    33121 aatatccctt attataacgc ctttatcatt tagtttttta attttctcta aatcttttgc
    33181 taaactaaat gcacagttat atgacctgtg tggatttctc gataaagccc tttctcctgt
    33241 atatcttact aatactttac cttcttctag ttcttctatc tctgtataat aagctaatga
    33301 ttctactaaa tctttcttat cattagtttt aaaaacagcc tcaattttgt cacatacaaa
    33361 tccatcttct ttgtttgact ttatatcaac taaattgtga tttctaaatt tatctttatc
    33421 tattttcttt cttagattga agtataaaat acctttttct ccatttacta ttgggaagtt
    33481 tccatctgga gaaaatgcaa attttggctg ttcattgaca ctaaagtaat gctccataca
    33541 ttcccaagtc gtctcttcag ctccacccac tatcaatcta atctttctct tcggcttttc
    33601 attaagttct cttaagaaaa gtaatgcata taaaatccct atcaaaggtc ctttgttgtc
    33661 attaactcct ctaccataaa gatagttatc tttttgacat actttaaaag gtttactctt
    33721 ccaaagttct ttattatata ttggcaccac atctatatga ttaagcaccc ctactacttc
    33781 ttctccttct ccatattcta tatgaattgc atatccatca aagtctttta caacaaaatc
    33841 tttgtctttt gctatttgaa taagcttatc gaaggcattt cttatttcta tcccaaatgg
    33901 ttgatttata tctgttgtac tttcatctct aattgaaggt atttcaacta aacttctaat
    33961 atcatttatg atattttctt gattggattt taaataatca ataattagtt ctttgtttac
    34021 tatcatctta attatttatc acccctttat attaatttta caaagcattt cagttcatat
    34081 ctacattata aattttgaat attatttttt caatatttca aatacttctc taagttacca
    34141 taatgatacg gtaaacaatc aacagattat gacaaaatca tactatacct attactaata
    34201 ttttaactta tctattacgt cttttttaat gtaagtttat tccaaaaata cataaaaaaa
    34261 gatgtagcct tagctacacc ttcttatatc tattcaactt ccattattat gctattaata
    34321 tctacatttc caggttctat cctatctttt actgttctct taacagaatc agcatcatcc
    34381 attataacta caggagttat tatatttaaa tcatttgacg ttataaaatc taaatctact
    34441 tccattatta aatctttagc ttttacctta tctcctgcct ttaccttaac atcaaacggc
    34501 tttccttcta gtgacattgt ctctaaacct acatgtatta atatatttgt attatcatta
    34561 ctcttaatca ttattgcatg ctttgtatca aatacattga ctatttcacc atcaacagga
    34621 gaatataact taccttcact tggtattatt gctactccat ctcccatcat cttttgggca
    34681 aaaactgcat ctggaacatc ttctaagttc actaaatttc ccttaaaagg gctatatatt
    34741 ttctcaatct tattttcttt tttcttaaat atattaaaca taacacactc tccacattat
    34801 aaaattttat gataatattt ttcttaaagc ttttgctaca ccatcattta cattagtatc
    34861 agttacaaaa tctgccatag attttacttc atctgtagca tttcccatag caataccaag
    34921 acctgcaaat ttaatcatgg atatatcatt ttcattatca cctatacaaa taacttcttt
    34981 gctatctata cctaatatat cacaaaattt tttaactgca ataccttttg aagtaccttt
    35041 actcataact tcaaagttta tctttccaga acttactact tctaaatctt cttgtttttt
    35101 aaattcttcc tttgcttctc tcaaagaatc tacgttttct gagaaaagta tacattttaa
    35161 aatttcatta tcagcttttt ctaataaagt ttcacaactt gcattttcta ttatttcaat
    35221 tctgtcttct tctttatttt tactatttat taatctatat ggatgttctt cacctatttc
    35281 attgttggat ataactattt tacagccttt aaaatgtttg cttaaattat acttttcacc
    35341 tattgtatag attttcttta gagcttcttt gctcaaaacc ttcttatact catatcccag
    35401 taatttaaaa tatgtcccat tagttgatat aatatatata tcatccccta aaacacttgt
    35461 aaaatatttc atagcattat aaggtcttcc cgtaactaag gctaccttga tacccttttc
    35521 catgacttct tttagtgctt taatattttc ttctgatact tcaaatcctt tacccatcaa
    35581 agtaccatcc atatcagtac aaattaattt atatcgcatt tgtatcacat cctagtaaga
    35641 tttttctaat atttcaacaa ggtcttcttt ctttccaaaa ggtaaaaatc ctaaaactgg
    35701 acagcttgtt atttgttcta attgttcctt tgttacatta aactcagaca tttttgtctt
    35761 aagtcccact ctctttaaaa aactttctat ttcatttcct aaagttttag ctgcttcatc
    35821 atcttccact ttttctaatt cttggtttag cattctcgct actttggcaa atttctctat
    35881 attatcctta tagaactttt ctgcaaattt tgggaacact atagccaaag cctcaccatg
    35941 aggaatatgt gtaactcctc ctattatttc acttagtgga tgtggtgctg ctgctccagc
    36001 atttgccagt gaacttcctc ctaatgtatc tgctactgct aactttgttc tgtattctat
    36061 attattttta tcttccatta ctttaggtag atagttaatg actaattcca tagatttttc
    36121 agacattatc tctgtaaaat cattagcatt tggatttata taactttcaa atgcatgagt
    36181 aaaagcatca aatgctgttg atgcagtaat tctctctggc agagttaaca taagctctgg
    36241 gtcaactata cattcttttg agaaacaatt ttgatgaaat attgtatttt tctcgcttcc
    36301 tctcgatatt actgctgctt gtgtaacttg gcttcctgtt ccagaagtag ttgatacagc
    36361 tattaatggt aattcttttt cacttacctt atcgtatatt ttaaatggat ttgtatatgt
    36421 actaaacata taatcccaat ctatcttttc taaaccaaaa gtcaatgcta atacttttgc
    36481 agtatctata cttgaacctc ctccaacagc taaaacaaca tctacagatt cttttttagc
    36541 taattcaaac ccttcattta ttaattctac agttgggttt ggctctactc tatcaaagtg
    36601 tacaacttct ataccttttt ctattaaatt caatgtaact cttttatata acttgtctaa
    36661 tggctctaca tttggagtag taactaacaa acatttcttt ccatattttc ctattattct
    36721 aggtaattca cttaaagttc cttgtccaaa atttattctt gatggttgat aaaagttaat
    36781 catatttttc ctcccttaaa ttattgcctt catattcaaa ttatacatat cataggattt
    36841 ttaaggcaat accttcactg ttaactctta tttactaaag cttatggcaa ttattagaca
    36901 atcaatgttt tattattacc atatcattat gtaaatttta ttaagtaccc atgttataat
    36961 tttataatca atcttattgt ataattgact taataataaa aatagagtat atacactttt
    37021 ttatgacaaa tagcttaaag gagaattaaa ttatgaaata tttgatagac agtgctaatc
    37081 ttgatgaaat tcaaaagtgt ttaaagtatg gatttaaggg aataacagct aatccatcta
    37141 tgtatcttaa agagaaagta aacttccatg aatttattga gacatgtgct aatttaaatc
    37201 cagaaatatt aactgctgaa gtcattggaa ataatttata cgaattaatt aattcatgtg
    37261 ataagatatt aaatataaat aaaaacacta taataaaaat aaatttctct gaagttggct
    37321 tagaacttat aaacatatta aatagtaaag gtgtaaaaac tgcatgtacc ttgattttca
    37381 atgtaaatca agcatcatta gctataaatg caggtgctga ttacctattc ccttttatag
    37441 gtagaaatga tgaaaatggg aatgatggta taaaaaacct tacagaaata tgtaacctta
    37501 tatcaataaa tggatataat actaaagttg ttgcagcttc tattaaaaat gtattccact
    37561 taactcaagc atctctttgt ggatgtgatt atgcagctgt aacatatgat ttatttaaaa
    37621 aagcttcttt taaccagctt acaatagatg gtgccaatac ttttgaaaga gattggtcca
    37681 aggttaataa atagtaacta agatttagga gggtttgcat tgaacaaaag attattagat
    37741 attgctgaat tattactcaa cagctcagac tatattactg tagatactat tgccgaagaa
    37801 ttaaaagtta gtaataaaac tattcgtaat gaccttgtta ttttagatga atggctttta
    37861 gagtttaatt tatccctaga taaaaaaact ggttcagggg ttattattct aggtaatgaa
    37921 gatataaaac ttaaagttat tagagatatc aatgataaat caaattgtat atatgcatac
    37981 tctcctgaag atagaaaaag gtatattcta agtaaattat ttattaaaaa ttctaagttt
    38041 aggattcgtg atatttgcaa tgaactacat gttagtagag ctactgtgca taaagacttg
    38101 gtagttattc aaaatttttt gcaaaacttt aaagtgactc tagttagaaa aaccaataat
    38161 ggagtatatt tagagggaaa agagaaagat attcgaaaag caatttttga acttgctacg
    38221 gttaataaaa gttatactga acttaaagaa atattattct cgaaatctaa tgaatgcaaa
    38281 gatacccctt caacaaaaat atttaaggag ctatttaact atgattttga gaaattatct
    38341 caaatcactc tacacacctt acaagtagaa aaaagtaacc ttagtgatga gtattatata
    38401 aacttcttaa tacatatagc tatatgtatt aaaagaattt caattaaaag atatattaac
    38461 ttatctgaag gtttttttag agaattatta gaacatgaat actttgaaaa atcaaaaatt
    38521 ttatgtgcta acctaagtga agcttttgac gtagaattta ttgatgaaga ggtctgttat
    38581 atccttcttc atatagaagg attacttaaa tcaataaaga aaactactac tcttgaacct
    38641 cttaaaaatg aagaaattac agagtataat ctatctgaag caatagctgt tcattgggga
    38701 agtatactaa atttaaactt aaaggatgat ttaatattaa taaagtctct tgctaatcac
    38761 cttaaatcag ttctacacag aataaactat gggtttacta ttacaaatcc catattaaat
    38821 gatataaaga gaacatttcc ttatacttat aaggctgcta aagagtctaa tactgttatc
    38881 aaacagttga tgaattatga agtcaatgat gacgaaatag gatatcttgc tttatattta
    38941 atatcagcaa tagatagaag caaatctccc cttaatacta ttttaatatg tcactgtagt
    39001 gatggtgtat ctaatttatt agtccaaaag ttaagttttg aatttaatca gattaatata
    39061 gttaaatcta tacctctatc ttctatttca tttacgaact ttgatgatgt ggacttaata
    39121 ctaaccactg ctcctgtaga ctttgaacat aatgctgaac tgataaatat aaatgctctt
    39181 ttaagtaaga atgatatttc tagacttagt acaattataa aaaaactata ttctgaaaaa
    39241 aataaaatat tatcttataa ataaacaaaa ataggcttgt ctcaacatag agataaacct
    39301 atttttcatt gtctaaatga taaaaatata tttgatttca tagaaaaagt gcctcatgaa
    39361 ctaaaaaatt cattttgaga cacctccatt ttttatattt aagcttttta tttaagcttt
    39421 tatatttttt aaacttttat atttaaagta aattttatta tttttattga gcacaagcat
    39481 tatttatatt attaatttct tcagtattct taccaaactt tgtagttaca aatcctattg
    39541 tttttattat gagtaataaa gatatcaatg aatatataga tatcataaaa ttcttactta
    39601 ttattccaga cgctactatt ataaatccat ctagcataaa taatataact ggcaacttca
    39661 gaaacttaat taccttatta ataagcattg caactaaatc agttccacca gtactacagc
    39721 cccttattat tgctatccct atagcagttc ctaccaataa cccacctatc actcctgcta
    39781 ctaatagatt gtcagttatg tgagtttgtg gtattacttt taagaataat gggcccataa
    39841 gagttatata taatgttttt attccaaaac ctttccctaa aaataataat cccattacta
    39901 aaagtggcat agatattcct aatgatatat tctcaacagg cattgataag aatgtgctaa
    39961 gtacgactga taatcctgtt atccctcctg gagctaatgt atgttctgca aagaaaaaat
    40021 taactgctaa tgccattaaa aatgctgata ttgttatcag taaataatct tttatcattt
    40081 cttttttcat ttaataacct cctatgatta tattatttca gtataaaaaa tcaattaaat
    40141 tagtctagct tcctgtagtt tttcataaaa ttaatgcttc cttaaaacat taagaaagca
    40201 tctcttttat catagtttat tatcttattc taaaccaaac tttgtagctg ctttatctat
    40261 agcttttcta caattcttaa cacctgctgt tataccatct ttatccttga atattgctga
    40321 agataatatt acaacgtctg gattacattc tattaatggc tccatattgt ctgctcttag
    40381 tccaccatct attgctaatt cacacttagg attcttttcg tctatcattt ttctagctct
    40441 ttttactaaa tcaacagcac tctttctcca tccccagtta tcttttccat cagtttcatc
    40501 aacaccatga acgactattt gcaatctatc tatatcatat atagcttcat caacaaaaca
    40561 taatggtgtg taacatccaa ttgttaatcc tactttcata ccaaattctc tacagtaatt
    40621 tattatgtat gcaagaggag cacctaaaaa atgttctgct ggtattatca acaagttaca
    40681 tcctgctgct gctatttttt ctataaataa tctatcacaa tctcttgtgt atatatggca
    40741 ttctattggt ttatctgtca ctggtcttat tgcttctatt atttgatgac cacccataag
    40801 ttgcatattt tttaagtcat gcatatctgc tgcatctgaa tgcacgtagt ctacacctgc
    40861 atccattgct tctttaacta cggctgatat atgaccgtaa tttacatgtg ctaatcctgc
    40921 tgctattttt atgtgtttca tatttgtata cctccatatt ttactttaat tagtattaaa
    40981 tattagtttt tgatattttt ttaatatttt ttaatccagt attactttta tttagcatta
    41041 cttttattgc tgtatatatt tcttttatga acttattctg cttttgttaa ctgtgaactt
    41101 attttgcttt gtaaattaat attacactga tatatttttt ttcacaacac tttgactact
    41161 ccttaaaagt acctttatat tgtggtaaat tatagacatt aattgtatat aaaaagttag
    41221 ttttttacca cattcttatg gcatttattg tctatactaa ctcaattgat atagctagtt
    41281 catttaatat ataatcagac tataaatata aatttactcg ataaaaagta ccattcataa
    41341 caatattaat gaaagggaga tgtaaaatga gaaactgtat tattgcccaa tctggaggcc
    41401 ctacagctgt tatcaatgct tctgcagttg gtatttatga aaaaaattta gaaactaaat
    41461 actttgataa agtatatttt ggtatcaatg ggattgaagg tatattaaac aaaaatataa
    41521 tagattcaga ctccttaaac aaagataatg tattaaattt aaagcaaaca ccttcgtctg
    41581 gtcttggttc ttgtagatac aaactggctg attataaaat aaattcttat gattatgata
    41641 gagttataaa tatactagat gaatatgaaa tagatacatt attttatata ggcggaaatg
    41701 attctatgga cacagtgatg aaattttctc aatactgcaa aaacactact tgtaaaataa
    41761 aatttatagg tattcctaaa acaatagata atgatttatt aggaactgac aactgtcctg
    41821 gatttggttc tgctgcaaag cttatttcta cactaataat ggaaacatac ttagattttt
    41881 ctatatacaa aaataatggt atatttatag tagaaactat gggtagagat actggatggt
    41941 tagcagcttc ttcttcacta gctagactta atgatactcc acttgttgat ttaatatacc
    42001 ttccagaaat tgatttctat gaagataagt ttatagaaga tgttagaaaa atatttaaag
    42061 aaaaaaataa ggcttatata gttgcgtcag aaggtataag ggataaatac ggcaacttta
    42121 tatgcgaaca aaaaacttct gctcatgata aatttggtca ttcccaatta ggtggagtaa
    42181 gcaactatct aaagaatctt atagtatcat catcaattac aacaagagta aaaaccttag
    42241 aacttggtgt aatacaaaga tgtgctatgc atttagcttc agatactgat ttaaaacaag
    42301 cagctgaagt tggtgcatat gggatagaac tatctaaaaa aggatataca ggagttatgg
    42361 ctatcattaa tagaacatgc aataatcctt ataagtatga agttagtcat actgatattt
    42421 ctaaaatagc taacaagaca aaatattttc ctaaagagtg gataaatgaa gaatgtaatt
    42481 atataactga tgaagcccta aattatctat atccacttat tcaaggtaaa ccagatatca
    42541 aatataaaaa tggactacct tatttttcaa ttatttacta ggaaattatt ataatttgat
    42601 atacactcaa ttctatcgct cttaaatacc taagtggctg ttaaataaaa ttataaattg
    42661 ttatatgaca gtcacttaat cgtttaatta tttaactgtt tagtttttta attttttaat
    42721 cttttttaat actaatacga tttgttgtaa taatatctca cacccatttt cattttggat
    42781 agattataat tagttagaca ataaatattt tgtcatgata ttattatata tagtgataca
    42841 aatagaaata cttttatcat ggctagaaaa acaaagatta cacaaaggat ttaaaaatca
    42901 aacaacttca attaaaataa atggttaaaa taacttctaa atcaactact ataaacaata
    42961 aaagaacata aagtagttaa gtctacaatt ataaaattag taagactata ataacttaaa
    43021 taaaattaaa gttaacaaag actattaaag ttagcaaata ttcctctacc taaataattg
    43081 ctttttataa agagttattt attttaattg aatttaattg aaatacgatt ttaactagaa
    43141 caatagatta atgtaatatt taatataaaa taattataat aattgaaaag gaagtaatct
    43201 atgatgaaaa tagcagtcat aacaaccgaa tttttaaaag agtttgtaga taattctata
    43261 aaaaagttaa atattaatgc agaaattgaa atatatatct atagagattt ttctcatgtt
    43321 ggagatttat atttagaaat agaagatagg tttgatggat ttgcagttag tggccccatc
    43381 cccaaaaaag ctattacaaa aaaggctgga actattaaaa aacctctagt tgattttggt
    43441 actgacttac aaagttacta tgatatgttt ctaaagctta tctttaaata taatacatta
    43501 gatttttcta gagcgtactt tgacttaaca gactgggcag ataatccaaa agatatatca
    43561 tattatttat caaatggcac atttggagac ttaatggata gtattgatga aaatgcatct
    43621 aaaatgagtt tatctgacat agcaaaactt gaaaaaaaga ttgcaaaaaa acatattaat
    43681 ctatggaatg aagggaaaat cgatttttct actactcgtt ttagtagtat tgttcctatg
    43741 ttacaaaatg caggagtaaa ctttcatttc atataccctg atatagattt attaaaaaat
    43801 acttttaata acttaataaa agatattcat ttacatagaa tgaagggaaa tcaaccaagt
    43861 gtaatatata taacagttaa agatacaaat tatgatgact ctactctaga ccaagtttat
    43921 aaaatattaa atagtattaa aaaagataaa ttaaccgatt ttataattga aaaaaatagt
    43981 aattctttta aaattttcac taaatgtgaa acgattaaat cattaactaa aaattttact
    44041 gcatgttata taaaagaatc tattgaaaat agtacaaata ttaaagtatg tgttggatat
    44101 ggaattggta atgatataaa gcaagctatg tctagtgcca taagtgctaa taaggaatct
    44161 aaaataaatc atttaaatta cagtttctta gtcaacgaaa attatgagac aataggacct
    44221 ttactgtgtg ataagttact tactgtttca aataaagtaa ctccacatat aaatacaatt
    44281 gccaaaagtt ctaaattgtc tactcttact attcaaaaga ttatatctgt tactgaaatt
    44341 ctacaaagag atgaagttac tcctaaggaa ttatcttcat gtttaaatgt aacagttaga
    44401 actgctaata gatttctaag tagtctctta aagtctggaa acgctactat attatatgaa
    44461 aaacaaaact caacaaaagg tagacctgaa agagtataca aattatttat atcagaaaat
    44521 aaatattaaa atccaaaatg cataaaaata ttttatcatc taatattaag taaaattata
    44581 tatgactttc taaaaggtat atctttgcat ctttttaaga tatacctttt ataatattta
    44641 ataatatttt atgttattat ctactaaaat tattttctaa ccattttact gcacaatgag
    44701 caaataaagc tgaaccataa actaatccct cttcattaaa aattgcttta ggattatgca
    44761 taccaaaatt atatccctga ctaatacttc ccattccaat ccataaaaat actcctggaa
    44821 cccttagtaa aatctctgaa aaatcttctg aacccattgc agatggaaag tctattacat
    44881 tttcatttcc tataacttct ttaacataag atacaatctc atctcctaca tccaaatcat
    44941 ttataactgc aggagtcccc attttaaatt ccactttagc atttcctcca aatgatttag
    45001 ctattcctgt agatatttca ataattctat tttttaattt ttctctaaca gattggtcaa
    45061 atgttcttaa agtacctgac atagatgctt tatttggtat agcatttggt acgcttcctg
    45121 cattaaacat accaatagtt aaaactacag gctctttctg aggtttttct cttgaaagta
    45181 tagtgtttaa tgctatttgt atatgtgaca ttatgtttat tgggtccact ccaaattcag
    45241 ggcttgctcc atgagttgct tttccttcta ctgttatttc aaatatatct gcagatgcca
    45301 tagctggacc acgtgaataa gctacttgac ctgtgttaag aaatttaccc accatactgt
    45361 gaaatgccat agctgcatcg acctgaggat tttctaatat accatcatca atcattgatt
    45421 ttgcacctct ggtagtctct tcatctggtt caaatacaaa ctttactcta cctttaagta
    45481 agtgcttatt atccataagt attttagctg ctcctaagag cattgctgtg tgattatcgt
    45541 gtccacaact atgagatgca tctttattct tacttttaaa aggtaaatcc gtctcctcca
    45601 taataggaag tgcatccata tctgccctta ataataaggt ctttccacca tttttactgt
    45661 ctaaaacagc tactattcca ttattagacg tcaatttcgg agaatatccc attttttcta
    45721 aagtactggt aacaaaggtt actgttttcg gtagattgca accaatttcg ggattttcat
    45781 gtaaatatct tctccatcta ataatttccc cttctattga ctgcgcttct ttaaaaaaat
    45841 ttttcatatt ccttcctcct aatcagatag tcagcaaaat ctcactttct tttagtaatg
    45901 aaatgatgct gatataaaaa ttataatttt atatattaaa tttcatgtct ttttaaggag
    45961 ttggaatatc atctggaata ggacatttat atgttttacc attcatagat ttatcaaatt
    46021 cttcttttgc ctttttagct atctctggat tatttaatat tttagctcca aacatagcca
    46081 taatctttga tgcatatatc ataccttttt ctcctataga acttcctgca caagatgtaa
    46141 actgccagct atgacctggt gctcctagat tcgtacaccc tgtaaaaaag tatgctgtcg
    46201 gaactatatg cattacatct ccaatatcag tagagccata actattaaag tttgtaacat
    46261 ttcctccacc ataatataga tgagttcctt ctggcaaatt atatttactt atcatagcct
    46321 tatattgttg tgggctttgt ctatctaatt cagctgcaaa atccaattcc tctcgagtcc
    46381 aaggctcttg tttaatctca ttcatacatt ctgatacaag atttgctaaa acatgattgt
    46441 ttaaagtatt ataacaccct cctaaaaact ctacttcaac ttcagtttca gtcatcattg
    46501 cagctccttt tgctaccttt acaagtcttt catatgtact ttctacagct tctctactta
    46561 aagctcttgt ataataccat actgatgctt tatcaggaac tatgttgggt gctactcctc
    46621 catctgtaat tgtataatga atccttacat cagaagtaac atgttctctc aaataattag
    46681 ctcccacatt agtaagttcc acagcatcta gtgcacttct tccattttga gggtctgagc
    46741 ctgcatgtgc agtctttccc ttaaagtgaa actttacaga gttaacagct gttgaagtac
    46801 caattgtagc ttcactaatt ttatttggat gaaaatttat agctaagtct aacccttcaa
    46861 acgctccacc tctagccata aatcctttac ctgttaattg ttcttctcct ggacatgcat
    46921 aaaatactat agtcccactt aagttatttt ctatcatctc tcttttaagc cctactactg
    46981 cccctacatg tgctgtacat aataaattat gcccacatcc atgaccatat gcacccaatt
    47041 caaatgcttc ttgttttgtt gaaacttttt gatttaaacc aggtaatgca tcaaattctc
    47101 ccataaaacc tataactggt ttacctgaac caaaactagc tctaatagcc gtggctaaac
    47161 ctcctacacc tacttccaca tcaaatcctt cacttcttag aaagtttgct gtattttcac
    47221 atgctttaaa ttctttaaat gctttttctg gattttccca tattttctta cttaaatcat
    47281 caagtttgaa tcttttttta tctatctcat ttatagatat acttcctatc attttctatt
    47341 cctcctataa atctatttac tatcaaccaa atataattgg acctattata ctagcaaatg
    47401 ccactgatgc aatggttaca gtaacaaatc ctcctataat catctttggt aataaataat
    47461 ctgttgccct ttgtttttct tcttcagttc cttccatagc atcaatacct tcattggaaa
    47521 ttatctgtgt tgcaggataa gctagcatac aagttacacc aattgcagct gacattcttg
    47581 gagaatatcc caatagtttt cctacaattg cagtaaatag tattataaat acagagccta
    47641 caacaagtat tcctatagtt ggaataatca tcccaaacaa tgctgttgga gttaccttag
    47701 caagtcctcc aggtaacatc aacatacaac caaacattat aattccatta gattgagatt
    47761 tatctaaaat tcctttttct aaaaaaccta ttcgtgtaaa aatcaaccct actaacaaac
    47821 atgctatgtt gggatttaaa taatagtttg caggggtaaa tcctggtatt aaagtagcca
    47881 atcctacaaa attaccaatc atagcaacaa atgaaagctt tgcaagatat actaaagtag
    47941 atgatttttt acctaaatct tctttaaaaa ttctcatact tggaagttta aaattacttt
    48001 ttgactcatc tttcaaaaaa tccccgttat ctcttttaaa ttttaattct ttatttatac
    48061 aatatgtagt tatcggaatg ccaaagaact tttgaaatga taatactaga attacaaatg
    48121 cagcaagttc aggtctattt gcagcttctg caacagttgt tacgataata ccagcaacag
    48181 tagaacccgc tattggaggt gctgctatta aagcatactc tctaccaaat aacatactac
    48241 ccactgttaa acagccaacc cctattccta caatacctac taatgcaatt acaaccgttt
    48301 tccattcatg acataagtct tcaagattta taagtgttcc taagttagtt attaataaag
    48361 ctataccaaa gttgctcatt gcagctaata tccctgatgc tcctgtaatg tcttttggta
    48421 aaatatttgt ccaaaatcct agtaaaaata taatacatac aaataacaat gttgaaattg
    48481 caccttttgt tttcttagat aaaaactcac taaaagcata aatcattaca catacagtaa
    48541 agcaagtaag tggattccaa aaattttcca ttgttgtttc ctcctaaata taataatttt
    48601 ttatcaataa aacaataatt ataaaatgta tattatgcag ttattcttaa ctacatatgg
    48661 tatagcttga tattttttga tgatattata tacgtcctaa attattccta aaatatctaa
    48721 ataaatataa ctagagttaa ctctctaaat attaactata gttatcaact tactagattt
    48781 ctttttgatt tt
//
LOCUS       DAEPHU010000024        46351 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 01A10CD0081
            SAMN05941466-rid12468953.denovo.024, whole genome shotgun sequence.
ACCESSION   DAEPHU010000024 DAEPHU010000000
VERSION     DAEPHU010000024.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941466
            Sequence Read Archive: SRR6291087
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 46351)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 46351)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068158.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 22:43:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,892
            CDSs (total)                      :: 3,805
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 87
            rRNAs                             :: 8, 1, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 55
            CDSs (without protein)            :: 55
            Pseudo Genes (ambiguous residues) :: 0 of 55
            Pseudo Genes (frameshifted)       :: 21 of 55
            Pseudo Genes (incomplete)         :: 28 of 55
            Pseudo Genes (internal stop)      :: 16 of 55
            Pseudo Genes (multiple problems)  :: 8 of 55
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..46351
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941466-rid12468953.denovo.024"
                     /strain="01A10CD0081"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            <1..489
                     /locus_tag="KR231_001461"
     CDS             <1..489
                     /locus_tag="KR231_001461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015984856.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HBH0003844.1"
                     /translation="DTTKTELTSNIETAKTELNTKIDQLIAGGSNVAYTQRVAIDDWV
                     EDAESGFKATVTHSLLTQRIVVNIIDATTKENIVPNFKIVDDNSIEIRSEVKVELNVY
                     VINGNAETHFINATVDDNRVSEMTTYSSKKIEDRLVNIEEKVNGGLSNIATSVNELIT
                     YC"
     gene            506..2218
                     /locus_tag="KR231_001462"
     CDS             506..2218
                     /locus_tag="KR231_001462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0003845.1"
                     /translation="MQTEWNFNYANYVQNVSLPPGRYKLECWGACGGAVDTSDWTDCA
                     KGGYSKGEIVFKKRTNLQICVGQSGYEKVSEGSSLTRSGFNGAGAAGKVTTGSFAYSK
                     YGGGATDIRLYHPSATWGNTESLLSRILVAGGGGGMKNNFASARSIGHGGGYVGVNGV
                     GRDRDFCGGGSQYQGGTSYDTEEYHGSLGKGGYGNIGIGGGGGWYGGAGSYSNECGGG
                     GSGYALNKDSYKVPGYIPTPEYYLENIVMTTGGNTTKADGYAKITLLQALPFLTVSSY
                     NSTQATFKADHTDPALLTKIEWFIDDVLKETITTNLTEEKTINYTLEDNALHTLKIVV
                     TDSNNATAEKVLSISKNIMPLPENVNLNDISTKLVEVNAGFKVGKTSIINTLALKNIE
                     ASLNNTLVELSEKIKTSFDSSDTSVQDLQNQVTQKNNTITQLETELSKRKRFITGTYT
                     FTKTDAENFNLSIYDKEGTSKTLTIPVNMGFSPSLIVLSGVTFSTTSKSYVYFDNVCN
                     SNFYNFGYNSDSTHSNPKAVGILNVSNVGYSSLVLTLYKLSMSEAVGIWAKEGATLTY
                     KIYI"
     gene            2239..2586
                     /locus_tag="KR231_001463"
     CDS             2239..2586
                     /locus_tag="KR231_001463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0003846.1"
                     /translation="MNRNNRIIYDQTGNIWLQTGEATGDIQEWSKITELNFLDVEFGS
                     IDYSKQYIESINPVTKEPIIKDIEVILTDEQKRLQALEKELSMLKEENKNRDSEIVNT
                     AFEVENIKLNNNL"
     gene            2598..2768
                     /locus_tag="KR231_001464"
     CDS             2598..2768
                     /locus_tag="KR231_001464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0003847.1"
                     /translation="MYNLLKLMIEQKNYSTKEDLQHKIDVFYAVNRITEEQYLELTSL
                     LNKEETPAEPIK"
     gene            2799..3365
                     /locus_tag="KR231_001465"
     CDS             2799..3365
                     /locus_tag="KR231_001465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0003848.1"
                     /translation="MTFKELVNKVRNLVLEAKNVTIEDTESKFTSENVEGALKECIDR
                     ADEAFQEADSGKTLLSTAIGSPATSEQTFQDYANYITGFKSNISNLETQLKSKYSIRY
                     GPIDGYDGNPFSANFGKSASYLIVYVYFRRSVYYYNPSGSSLGSNTGGSERAWITIDS
                     NKTGFSVHSYDTSYEPYPFTGYYIACFA"
     gene            3396..3686
                     /locus_tag="KR231_001466"
     CDS             3396..3686
                     /locus_tag="KR231_001466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0003849.1"
                     /translation="MEEISINLLCAVAGVVISYLAFRNSSNRKIQDDTETTTKLEQQI
                     TFLCENVRDIKHDVAKFNTSFLDISERVAKVEASTKQAHLRIDEIINRIGGK"
     gene            3690..3947
                     /locus_tag="KR231_001467"
     CDS             3690..3947
                     /locus_tag="KR231_001467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin family protein"
                     /protein_id="HBH0003850.1"
                     /translation="MDNLISFIPEQLLILVAALYVIGAGCKKYKQLDNKYIPVVLLIL
                     GIGFSIWMLGLNPVAVLQGVICWGVAIGVNQTYKQFKDGEK"
     gene            4208..5071
                     /locus_tag="KR231_001468"
                     /pseudo
     CDS             4208..5071
                     /locus_tag="KR231_001468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429958.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="Abi family protein"
     gene            5150..5962
                     /locus_tag="KR231_001469"
     CDS             5150..5962
                     /locus_tag="KR231_001469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HBH0003851.1"
                     /translation="MKICITVGHSILKSGACTSADGVVNEYQYNKSLAPVLADTFRKE
                     GHKADVIICPEKQFKTKAEEKTYKIPRVNSGGYDLLIELHLNASDGQGKGSEVLYYSN
                     KGLEYATRICNKLGTVFRNRRAKLDKGLYILNSSNPTAVLIESFFCDNKEDYEKAKKL
                     GHEGIAKLIVEGVLNKNINNEGVKQMYKHTIVYDGEVDKISATVVGWGYNDGKILICD
                     IKDYVPGQTQNLYVIGGAACEKIGSMTKEKFTMIKGNDRFDTLYKALDFINR"
     gene            6056..8455
                     /locus_tag="KR231_001470"
     CDS             6056..8455
                     /locus_tag="KR231_001470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding repeat-containing protein"
                     /protein_id="HBH0003852.1"
                     /translation="MIFKKYIKSLLIVVSVTLIMNKSILFVNALDLESNNNIKSYKRK
                     NVKEIDISNKFVDESFRRDIVEKVLDNRDDPLTNEVASKDNYKIYESDLNKIESCLEL
                     DLHKNPDVSNPNKIDNLDGIENFRNLEKLDCSSNNLESVDLSKNIKLKYLDISGNKIL
                     NINLKNNNLINELHCDANKLSSLDLKNNKNLVSLFFTSNELTEIDLSNNVNLENLQFL
                     NNNLKSIDLSHNKKLKSLNCTNNKLKSLNLSNNVFLKNLSCSGNNLSKLNIKGLTSLE
                     YLGCAKNKLQDLDVSTNIKLDSLFCGKNSLTKIDISKNKELKSLECSGQYIEKSIIKN
                     GENIVVDIGIENSKLKELYPQNYNISTGFLTWKNISEFPNNVSYSLEYEYGPVNDVET
                     MDVNISIDKLVKCRIRYIDYDGSIINEKEISDNSSINEIQINPQRENYEFNGWRNNKD
                     EKIYTSEQVSKLVFDDSTDFIATYKRKSTGSSGSSGGTSSKEDFNIAPSKEKLTGADR
                     NETSVKISQKGWNKADNIVLINDSSISDALSATPFAKSKDAPILLTKNNNLNKLTEKE
                     INRLEAKNVYIVGGLKSVDEKVVSDLKKKGLNVIRISGNDRYETSIKLAKELDKNSNL
                     SKVVVVNGEKGLADAVSMGAISAKEEMPILLTNQNDDMKDIKDLIANKNISKSYVIGG
                     ESLFNNKEVNNTLPSVTKIAGSDRTETNSKVISHFYSKDTLNDLYVAKNGMNKQDDLV
                     DALSVGVLAGKTESPVVLVGNGLDDSQKELIKNKKFKNITQIGGNGNEKAFNEVENLV
                     K"
     gene            complement(8496..8681)
                     /locus_tag="KR231_001471"
     CDS             complement(8496..8681)
                     /locus_tag="KR231_001471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB/MazE/SpoVT family DNA-binding
                     domain-containing protein"
                     /protein_id="HBH0003853.1"
                     /translation="MILLEQRKLRVAFNKSGKGSFTPRLILPMSWIKEMNISPDERDV
                     LVTFEDGKIIIEKTENE"
     gene            complement(9229..9405)
                     /locus_tag="KR231_001472"
     CDS             complement(9229..9405)
                     /locus_tag="KR231_001472"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0003854.1"
                     /translation="MEQKESKIVYSKGGSGTYSAKISLPLSQLEKMGFTREKRKAVVI
                     FKEDEIIIKKSDEE"
     gene            10122..10799
                     /locus_tag="KR231_001473"
     CDS             10122..10799
                     /locus_tag="KR231_001473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="manganese catalase family protein"
                     /protein_id="HBH0003855.1"
                     /translation="MFKHDKALLKEVKVERPNPQYAVLMQEQLGGANGELKAAMQYLS
                     QSFRIKDPQIKDLFLDIAAEELSHMEMVAQTINLLNGHDVDYNSVNTGEIETHVLTGL
                     SPVLINSSGAPWTANYVTVTGDLVADLLSNIASEQRAKVVYEYLYRQIDDKYVKETID
                     FLLNREEAHNALFRDALNKVKDTGSNRDFGVTEDSKLYFDLSTPGPNHDTKIDINPPS
                     FEKPLKK"
     gene            10973..13009
                     /locus_tag="KR231_001474"
     CDS             10973..13009
                     /locus_tag="KR231_001474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin domain-containing protein"
                     /protein_id="HBH0003856.1"
                     /translation="MDSNRKPNNLINEKSPYLLQHAYNPINWYSWNDEAFKKAKEEDK
                     PIFLSVGYSTCHWCHVMEKESFEDEEVAEIMNRNFVAIKVDKEERPDVDSVYMTVCQA
                     MTGSGGWPMTIIMTPDKKPFFAGTYFPKYSRYNRPGVIDLLENVSEKWNTSRDILIKS
                     GDEIIEALKDDFGVKNTEGDLSKEMLSSSVRVFKAIYDEKYGGFGNAPKFPSPQNLMF
                     LMKYYSIEKDKDVLKMVEKTLDGMYRGGLFDHIGFGFSRYSTDKKWLAPHFEKMLYDN
                     AMLTIAFLDAYKITKKELYKEIAIKTIDYVVREMKDKEGGFYSAQDADSEGEEGKFYT
                     FNPLEIIEVLGEEDGIFFNNYFDITSSGNFEGKSIPNLIKNKEYERHNEKIADLSKKV
                     FEYRKERTSLHKDDKILTSWNALMIVALTKAYSTLKNDIYLEYSNKCLNFINNNLVNE
                     SGRLLARYRDGSSDYLAYLDDYAFLIWAYIELYESTFNMKYLEKALNLNESCINLFWD
                     YEKSGFYIYGKDSENLIARPKDLYDGAIPSGNSVQLYNLIRLAKITGDNRLEEMSYKQ
                     LKLYVDNVKSSPTGYSFYMLSLMFELYSTKEIICIFKEDSDLIAFKELISENFIPNAT
                     FLAKKYNEENTIIGFLNNYILKDDKTSYYVCQSNSCSQPINDLQKLKDMILGVE"
     gene            complement(13200..13766)
                     /locus_tag="KR231_001475"
     CDS             complement(13200..13766)
                     /locus_tag="KR231_001475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HBH0003857.1"
                     /translation="MDYSNELKELFLMNQTYATLFTLTNKIQIEGDKYFGILTSRQYM
                     TILSILHLPEEETTLNNIARKMGTSKQNINRLVANLEKNGYVDVIPSPHDKRAINVKV
                     TDLGKKVMVTCSRTGINFMADVFHEFTKDELETLWSLLKKMYRFNGEEQDGFEEDANF
                     MEYEEIDKIKSEALEEFAKRRNRVNKKD"
     gene            14054..14989
                     /locus_tag="KR231_001476"
     CDS             14054..14989
                     /locus_tag="KR231_001476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HBH0003858.1"
                     /translation="MKCTNFTFKGEEGLDIYTYKWEDENIKKPKAVIQIAHGMAETAQ
                     RYETFAKVLTKNGYIVYINDHRGHGKTAKIIENVGHLAEKEGFRCLVEDMYTLTNIIK
                     KENEDLPIYLFGHSMGSFASQRYIMDYSNNLSGLILCGSNGKQGIILNLAHLIINREI
                     KKYGRRSKSNKINNLIFGGEIIRRNEKTKFDWLSRDKEQVEKYINDPFCGVVCSCGFF
                     YDLVQGLKEIEDKENLKKVPLDIPIYIISGDKDPIGKNGKGVLRLRDRYIKLGVKDVT
                     CKLYKDGRHELLNEINREEVFEDIICWLNNKIEIL"
     gene            15454..16668
                     /locus_tag="KR231_001477"
     CDS             15454..16668
                     /locus_tag="KR231_001477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBH0003859.1"
                     /translation="MQIKIGKVIQCLRKERNLTQEQLAKFIGVSTPAVSKWESGNSYP
                     DIELLPLLADFFNVSIDKLLNYKIDLSEEEVMKIYKELESGFARIEIDLSTEEPKEEF
                     RQDLESVKKLSNMYIEKYPKSYLLKLRICSLYQMYSYKFGKSELNDRVKETMNILEDI
                     VRNTDDIQIKETALIILSNAYCMLEDYEKAELYLNMIHKSIGDTSVNLAMIYLKQNRL
                     EEAEILLQNKLFSNVFNISMDCKGIINVYKNQYKELKKKLENRNFNKNAIEREMEYIK
                     NKLLGYANLSLEIKKMLSEDKGAFFSMYMDYMELSLIFLFFNMKEEAKKALYSLKEIL
                     EKYPIHESLDVSQMRFFDKVESKNLYTFNIYTNLLIVLNDDSYNELREEPIFKDVIEK
                     ILDMEKMLKNKE"
     gene            complement(17088..17609)
                     /locus_tag="KR231_001478"
     CDS             complement(17088..17609)
                     /locus_tag="KR231_001478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBH0003860.1"
                     /translation="MKFKRLRTSENKLCYKAMELYKISFPFHEQRKSSLQEEILKNKE
                     YQFNLIYDKNQFVGIILCWETDDFIYVEHFCIFPEMRNNRYGQRALELLNKKGKTIIL
                     EIDLPIDEISIYRKAFYERVKYKTNNYEHIHPPYHEKFNGHNLIVMSYPEKLSKMEYD
                     KFNHYLRNNVMSF"
     gene            17965..18762
                     /locus_tag="KR231_001479"
     CDS             17965..18762
                     /locus_tag="KR231_001479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="G5 domain-containing protein"
                     /protein_id="HBH0003861.1"
                     /translation="MEKREKRIIISSLLSVSILMGLVSIYSILNKEDIILTVKGQEQK
                     VSSFKKTVEELLDEQGIKYNSEDKINPSLDTELKDDMKIKVVKVTKSKKEEIEKIPFD
                     TKHVNDSNLLKGKSKVYQEGQEGEKKLVYNLTYHDGKLVKKVLSKEVISKEPTTKIIK
                     YGTKEKVLIASRGANIRGGKHMKVVATAYAGDTITSTGTTPRWGVIAVDPRVIPYGTK
                     VYIPKLGMTFVAEDCGGAIKGNRIDIFMNSEGKASNWGRKSIDIYLH"
     gene            18872..19462
                     /locus_tag="KR231_001480"
     CDS             18872..19462
                     /locus_tag="KR231_001480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SGNH/GDSL hydrolase family protein"
                     /protein_id="HBH0003862.1"
                     /translation="MKIVCLGDSLTYGFGVSRSNSWTNIVNKETRLEIVNKGINGDTT
                     SGMLARFNEDVVKNSPDIVFIMGGTNDFIAGAGNEIINSNIMAMVHQSYSKNIIPIIG
                     IPLKPDIPNVREDWSCFTDFNIVSQNLESYSYWIKKFCMTFNTNFVDFYSEYNKNMEL
                     EGYKKLYFDGLHPTKEGHRIMADIFINSINKYIEEL"
     gene            19528..21225
                     /locus_tag="KR231_001481"
     CDS             19528..21225
                     /locus_tag="KR231_001481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-sugar mutase"
                     /protein_id="HBH0003863.1"
                     /translation="MDYTKTYEEWIKGSYFDEDTKLELENIKNNEKEIEDRFYKDLEF
                     GTAGLRGIIEAGTNRINKYTVRRATFGLANYILENTTKEETSRGVVIAHDNRHKSRQF
                     CIESANTLAACGIKAYIFDSLRTTPELSFAVRSLNAIAGIVITASHNPPEYNGYKVYW
                     EDGAQVMPEIANAITEKVNSIHDYSTIPTLTEANKNLVVLLDESQDTKFIEAVKSQII
                     RKDLVKNVGKSFKIVYTPLCGTGNVPIRRALKEVGFENIIVVPEEENPDPNFAGLDYP
                     NPEEKKALNRGILLAKEKGADLVIATDPDCDRVGVAVKTTTGEYALLTGNQIGGMLTH
                     YIIEGLKENNKLKENPTIIKTIVTSEFGADIAKANNVDVLNVLTGFKFIGEKIKLFEQ
                     NKNRSYVFGYEESYGYLVGTHARDKDGVVSSLLISEMAAFYYSKGMSLYDGLIELYKK
                     YGFFKEQTISLTLKGIEGVEKIKEIISYFRENQIDYINSIKVVDKKDYKNGIDNLPKS
                     DVLKYFLEDESWVAIRPSGTEPKLKFYIAVKGASDIEADKKIQGLKKYIDDMVEKLK"
     gene            21439..22278
                     /locus_tag="KR231_001482"
     CDS             21439..22278
                     /locus_tag="KR231_001482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YihY/virulence factor BrkB family protein"
                     /protein_id="HBH0003864.1"
                     /translation="MFGIDKKLIEYIIAKSNYSELSSKSAEVSFFLMLSIFPFLIFTI
                     SSIAYIPILHLNKYIALFRNMMPEGAFAVLSSIIVSAIDNRNLKFLAVSFVLTMWTFS
                     RAVKALIKGMNRAYKVKETRSFFKILSISFLFTIMLLVLIFLSMIFLVYGEKIGYFIF
                     NLVGLDEIFIKIWDILRYTVGIITIIVIFTLLYKYTPNKKLTIKESAPGAIFATFAWF
                     LVSFLYSYYTNYYANYEVIYGSIAEIIVLMTWMYFSSWSIVIGYEVNSRLYFRKIRHE
                     MLK"
     gene            22795..24651
                     /locus_tag="KR231_001483"
     CDS             22795..24651
                     /locus_tag="KR231_001483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PAS domain-containing protein"
                     /protein_id="HBH0003865.1"
                     /translation="MDTHNKYVNFIKNIPVPFLYCRIVKRQEDIEYRVEYISKGMGKV
                     LQLEEGICDKNILDVLPVFKSKKYFKELFSNEVDCIKRYIPTLKNWINIKKQIIGDSY
                     IILYFGKIVFDYRQIIDSFDKKEKVAYIKDEEGIYIDCSENLIPILNNNIKTTKDIFG
                     KNDIEVWGENTGKLFRDDYREGVSSKKRFLQNLFEYEETFFMVEKYFLYDEDELLGTI
                     GIVDNIIYSGYSNRNYNSKDLMKMIEHSIPENMFYKDVYGNYIGFNSGFLNLACMNKE
                     ELLGKNSYKISEEEALIDKIFESDKGVVENKKVVTFELNISMNDENKCIEITKRPFFD
                     SYGSVIGIIGTARDISRRKRLEEEMDKTRMEFFANLSHELRTPINLISSSLQVIEKKE
                     ADLIESNDTLKRNLGIIKQNGNRILRLVNNVIDFTKMQSGYLDFKPEESDIIAFIEEI
                     CMSVADFASQNNIQLTFDTEIEEFSMLFDSEKLERIILNLLSNGIKYNKKDGKINIFL
                     YVKDNVFNMKISDSGIGIPKEKIDKIFNRFEQIDNELSYRVKGSGIGLSLVKSLVELH
                     EGSISLKSQLGIGSEFIVSLPVRSKNNIEKYNHKREISNELSKKLEIEFSDL"
     misc_binding    24734..24974
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     misc_binding    25040..25275
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            25360..26577
                     /locus_tag="KR231_001484"
     CDS             25360..26577
                     /locus_tag="KR231_001484"
                     /EC_number="1.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine dehydrogenase"
                     /protein_id="HBH0003866.1"
                     /translation="MENKVKIGVLGYGVVGSGLIDIIDNNKEKRNIEIVGILVNNLEK
                     HKDKKYSNIITNNIDDIFNKDIDILVEVMGGLEPSLSYIKKALNNKIHVVTANKDLLA
                     ECGDELAKLASENKVSIKFEASVAGGIPVLKPIIESLEGNNIDSINAILNGTTNFILS
                     KMYDENLSYDMALRQAQELGFAEANPESDVLGYDAARKLSILSTLAYDNRVYWKDVYL
                     EGITDIDEKDIEYAKKLNCKIKLIGQSKYENDKVSAFVRPVLVEKDNILARIDNEFNA
                     VIVNGDSVGEVSFVGKGAGSLATGSAVYSDVIDIIDNRVSSIDSFTKDKIQVNKIVRE
                     KCGALLRFKKCNKDEILNIVENCLVKFDILNDDDELAIMVYADSEYEINNSLCLIKDK
                     GYCEKMNKMLKIS"
     gene            26694..27188
                     /gene="cdeM"
                     /locus_tag="KR231_001485"
     CDS             26694..27188
                     /gene="cdeM"
                     /locus_tag="KR231_001485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exosporium morphogenetic protein CdeM"
                     /protein_id="HBH0003867.1"
                     /translation="MENKKYANGGYSEDWYERGESTAKWFQNDREEYERAAYDEDRER
                     RGSNCGCSDSGENRPRNCERFRREAEIREREAREAFCESSERKKEALAYECEARKLWE
                     EAEKYWDEYSKYNYKGIEYLAEAARLFDEGMECEARRNGNNGGNNNNCCHKCHKCNCN
                     CCRK"
     gene            27453..28718
                     /gene="hisD"
                     /locus_tag="KR231_001486"
     CDS             27453..28718
                     /gene="hisD"
                     /locus_tag="KR231_001486"
                     /EC_number="1.1.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidinol dehydrogenase"
                     /protein_id="HBH0003868.1"
                     /translation="MKSIKTSSMKEKVDEKILREQVSSIIEDIRNNKDVALKKYNEKF
                     DRNTRDEFRITKEEIKEAYKHVDDEFINNLKIAAKNIREFAKAQKLSFENPFEKEIYP
                     GVILGQTNIPIESCLAYVPGGQYPLFSTALMLIIPAKVAGVKRIVACSPTMKNTEKIN
                     PKTLVAMDIAGADEIYATGGVQAIAAFTYGTEKINPVDIIVGPGNKFVTEAKRQCYGQ
                     VGIDFVAGPSEVLIIADETSNPVYIAADLLAQCEHDLNARGILLTNSLEVAQKVEKNI
                     ESMLKDLPTKDIAYSSWENNGEIILVDDMEEAIKISNFYAPEHLEVAVNEYNDICDRL
                     TNYGSLFIGNLSAEVFGDYVSGTNHTLPTLKASRYTGGVWVGTFIKTCTKQIFNEKAI
                     QSLAPVAEKLAKEEGLYAHAKAAEVRFKK"
     gene            complement(28921..29673)
                     /locus_tag="KR231_001487"
     CDS             complement(28921..29673)
                     /locus_tag="KR231_001487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HBH0003869.1"
                     /translation="MSYFQYQGNSCFYKEYGQGKPIIFLHGNTGSSNMFKALVPLYVE
                     NFRCILIDFLGNGQSDRVSQFSPDIWHDEALQTIALIEHLNCGKVGLIGTSGGAWAAV
                     NTGLERPDLVEAIIADSFDGRTLNDNFIDNLITGREKSKQDIQARKFYEWCHGKDWEN
                     VVNLDTKALLQCANEKRPLFHKELCKLEMPILFTGSKEDEMCRHNLEEEYKQMATFIS
                     KASIHIFSQGGHPAILTNADEFAQLAKVFFKY"
     gene            complement(29791..30060)
                     /locus_tag="KR231_001488"
     CDS             complement(29791..30060)
                     /locus_tag="KR231_001488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0003870.1"
                     /translation="MSYQNSIDLLPKELIEQVQEYIDGKVIYIPKKQEHKKHWGENTN
                     TKQVLASRNSQICINFQNGMSIKQLSEKYFLTEKSIQRILKQQNL"
     gene            30535..31629
                     /locus_tag="KR231_001489"
     CDS             30535..31629
                     /locus_tag="KR231_001489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HBH0003871.1"
                     /translation="MKNIVGKPQTIKKVNEDLIKNIIKNEGPITKPEISNITELSLAT
                     VNKIVEQLALKNEVKVSGLSESTGGRRAQLFEINANLEHIIALYYYRNCCIGVVANLL
                     GEIIYQEEFNIRMDTYENVNQDTFFVIDTLIKKEKGNNIRAIGIGVPGVVKKGVVKNI
                     PTIKSWEGINLENLIKSKYNTKVFIENDTNITTIGIYQKQYKDKYKNMALMYLEDGIG
                     SGIVINGELYLGSTNFAGELSYLNIEFGKYNSNNLNLEDYIMSLRKRYLESKDNKFKK
                     EILSIISNFIRTLVCVLNPQAMIIQCSILTKSDMEFIEKDVSNNVGEENFPKLIKVES
                     LREGSINGVISMCLKETDYQYSLSNKKGGY"
     gene            31631..32581
                     /locus_tag="KR231_001490"
     CDS             31631..32581
                     /locus_tag="KR231_001490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylglucosamine kinase"
                     /protein_id="HBH0003872.1"
                     /translation="MKYLVSIDGGGTKTKFCVSDLDGNILKEHTTGSTNYKSVGIKKT
                     YENINNGFKKILKDLYIDYDDIEYTVFGISGCDSPNDYKIIMDEILKIGINKEKIYLA
                     NDAVLAFYAQADSPGLVIVAGTGSIILGIKEDGEIYRVGGWGYNFSDLGSGYDIGRKL
                     LKKVLLYCDECHEYSDLFSCVLDFFGANSFEQLAYMITDINNNVEIANLASLVIDCAE
                     QGDKLAIEILRESSTELSKLAQVILRKISNPMKVDKSEINIVLSGGTLNKTVYAQMLM
                     NNLKTENTDKNLKFISQENQPVYGGIRLAMALANRRVKHG"
     gene            32574..33758
                     /locus_tag="KR231_001491"
     CDS             32574..33758
                     /locus_tag="KR231_001491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0003873.1"
                     /translation="MDRKKVIVQIFTGGFKAKEIKFNDIKCKLLELLDCIDIEKVIMG
                     WSVDEELYVETKKLLNKYNVELYLWLPCFSEIGLLEKSNLLIDYMGKEVKGYALQEDE
                     NFEFYCPNNKENIKNIKKIYSTYFSDIKFDGIFLDKIRYGSFSNKLNGVFNCFCKDCL
                     NIYEKNNIDKESLMREMNNVSKGVIDNEDTPFGITEYINGKYKFKNKIWEDFFETKNQ
                     NIYKALLEISNYFKSKGLKIGIDTFSPFISYFTGQDLEKLQEVADFIKPMMYRTTKAP
                     AGLPFEFERFIDESIHKNKEIGKRNFLDILGIKEYEGDVYPIEFVLEEIDFMTRNLNK
                     DIYVGVEINKKEIISPVTPKYISENISNINKTTVKGYVLSWDLLSAPKENIDEIIKWF
                     RN"
     gene            33771..35267
                     /locus_tag="KR231_001492"
     CDS             33771..35267
                     /locus_tag="KR231_001492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter ATP-binding protein"
                     /protein_id="HBH0003874.1"
                     /translation="MSKILEMQQIYKSFGKVDVLKGINFELEKGEVRALLGANGAGKS
                     TLIKILGGVHSQTKGKVILTGNEIMFKNPHHSKENGISIIYQELSLIPTLTVLENIFL
                     GREILKGSVFLNKKDMLEECMKICEDFDFNIDPHMVVSNLSVANQQMVEIMKAVSCNS
                     EIIIMDEPTTSLTNNEKDGLFKIISRLKSKGKTIVYISHILEEVFKVCDSASIMKNGI
                     MIGTYDVEDLTKLKITQLMTGNDNHKLIEKKDYTFAKYEEPPVLEVKNISWSNKIKNV
                     SFKVYRGEVVGLAGLVGSRRTEIINLIFGIDNKDSGDIFINGKKVDITSPKVAIKNKI
                     GLIPEDRKNLGLILEQAIYTNSSSVQIDKFKKFLFIDRNKEIEFSKKGVKELGIKVND
                     VKQEVKELSGGNQQKVVVSKWLEKDLDLIIYDEPTKGIDIAAKEDIFNTIKEFSSKGI
                     GVIFISSDLEEVIRVSDRILVTREGSIVDDLKNENIQVQDIMNSIFNV"
     gene            35290..36240
                     /locus_tag="KR231_001493"
     CDS             35290..36240
                     /locus_tag="KR231_001493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBH0003875.1"
                     /translation="MKKAFEKLNLRDYGVLLGFLALCIAISIATPSFLGKQNILNLLR
                     QSSIIGIISAGMTFVIISGNFDISVGAVAALAGAITMKFATGGTNLFASMLLGVAICA
                     VIGLINGIVVAKINVPSLIATMAMVTIVRGLLLMLTGGYPITENIPILDYIGNGYLFN
                     IPIPVVIFFIVVLASFIVLNKTKFGRYVYSVGGNQEASKLNGINVDSHKVKVFIINAV
                     LAGIAGIVLTGRLGTATAIAGEGYDMDAIASVVIGGTSVAGGSGSVLKTVIGVLLMSV
                     INNSFNLLGIDVYFQYIFKGLIILAAVGFDSYSKKKLASR"
     gene            36261..37223
                     /locus_tag="KR231_001494"
     CDS             36261..37223
                     /locus_tag="KR231_001494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430005.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter substrate-binding protein"
                     /protein_id="HBH0003876.1"
                     /translation="MKKLMKHLALLLSLVMIFGLVGCSNGGDKEKNGEKKIAVLLPGS
                     TGYFVATKQGIDAKSKELGVSVEYADAQWDASKQLSQAEDFMAKGVDMIALCGVDSAV
                     SERIVKAANDSDVPIVAFTNSIGSNPTGEFKGLVTYIGQNEEETGALTGKIAKNLLGE
                     TGGKAVLIEGVPGTTPQVLRKKGLEKELKDSNIEIVYNQTSNWEKEQALKVTEDLIQK
                     KTDFNVIICQDDNSATGAGQALKDAGLKDKVKVIGLGGSKDGLKAITDGLIDGTTYMS
                     AVEEGGLVIEKASKFLKGEKIEPVTQIKQVEVNKDNISEFKGEW"
     gene            37595..38227
                     /locus_tag="KR231_001495"
     CDS             37595..38227
                     /locus_tag="KR231_001495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HBH0003877.1"
                     /translation="MARRLFLERIGLIFLGSAILAFGVYNFYYLNNITEGGVLGILLL
                     LKNLFNIQPAIANVVIDGLLLLVGYKFFGKKFLIYSIVASITFSVLYDLFEAIGPLVP
                     QSQNMLLSTILAGVTVGTGVGIVVKAGCASGGDDALALVISKTTSLNIGQVYLATDVI
                     VLLLSLFYLSAFDIFYSLIAVTISGKVIDFIYYHGKSLDMDISNDIVPEC"
     gene            38638..38730
                     /gene="kdpF"
                     /locus_tag="KR231_001496"
     CDS             38638..38730
                     /gene="kdpF"
                     /locus_tag="KR231_001496"
                     /EC_number="7.2.2.6"
                     /inference="COORDINATES: protein motif:HMM:TIGR02115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="K(+)-transporting ATPase subunit F"
                     /protein_id="HBH0003878.1"
                     /translation="MEGLPMWFLAVVIIMLIIYLVYALINPEKF"
     gene            38771..40453
                     /gene="kdpA"
                     /locus_tag="KR231_001497"
     CDS             38771..40453
                     /gene="kdpA"
                     /locus_tag="KR231_001497"
                     /EC_number="7.2.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015391009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="potassium-transporting ATPase subunit KdpA"
                     /protein_id="HBH0003879.1"
                     /translation="MFMVQIVIVLAIFMILVIPMGKYLYHIATNQKTFGDRLFDKVDN
                     FIYKVCSIDKKKEMNWKQYALALLFTNAVMVFIGYIILRTQSMHIFNPSGIKSMEQGL
                     SFNTIISFMTNTNLQHYSGESGLSYFSQMTVIIYMMFTSAATGYAAAMAFVRGLVGKK
                     KTLGNFYVDLIRITTRVLLPGALIIGLILVTQGVPQTFAGTETVTTIEGKLQDIARGP
                     VAALESIKHLGTNGGGFFGSNSSHPFENPTIISNIVEILSMMILPGACVVAFGHMIKN
                     KKQGWVVFGAMSIIFLIGLVVCFKAESAGNPILSQLGLNQSMGSMEGKEVRFGIAQSS
                     LFTTVTTSFTTGTVNNMHDTLTPLGGLVPLLNMMLNVVFGGKGVGLMNMLMYAIIAVF
                     LCGLMVGRTPEFLTKKIEGKEMKLIALLIILHPLLILMFSGLSVAIPAGLEGISNPGF
                     HGLSQVLYEFASSAANNGSGFEGLGDNTMFWNITTGIVMFFGRYVSIIVLLAISSLLA
                     SKKAVNESIGTLRTDNFTFTIVLVLVVLIVGALTFFPALALGPISEHLVLWH"
     gene            40478..42535
                     /gene="kdpB"
                     /locus_tag="KR231_001498"
     CDS             40478..42535
                     /gene="kdpB"
                     /locus_tag="KR231_001498"
                     /EC_number="7.2.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010966942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="potassium-transporting ATPase subunit KdpB"
                     /protein_id="HBH0003880.1"
                     /translation="METKKTKFITKDIFKTSIIEAFKKLNPKYMMKNPVMFVVEIGFI
                     VTLILTIVPSLFGDEGNNLRAYNGIVTIILFITVLFANFAEAVAEGRGKAQADTLKKT
                     RKDTVARVIDTLGNEKMISASELKLGDIVLVNAGEVIPNDGEVIEGIASVDESAITGE
                     SAPVMRESGGDFASVTGGTTVVSDWLKIRITTKPGESFLDKMIALVEGASRQKTPNEI
                     ALNTLLVGLTLIFMVVLISLYPMANYAGVKIPISTMIALLVCLIPTTIGGLLSAIGIA
                     GMDRVTRFNVIAMSGKAVEACGDVDTMILDKTGTITYGNRLASEFIAVGNADSKDLIN
                     YSVMCSLKDDTPEGKSIVDLGMKLGSTGKTKEAEEAEFVEFSAQTRMSGINLADGRAI
                     RKGAYDSIIKRVKESGGTVPEDLEENVNRVAKLGGTPLVVCVDNEIYGIIYLKDTVKS
                     GLVERFARLREIGIKTIMCTGDNPLTAATIAREAGVDGFIAECKPEDKIDAIKKEQLE
                     GKIVAMTGDGTNDAPALAQADVGLAMNSGTTSAKEAANMVDLDSDPTKILEVVEIGKQ
                     LLITRGALTTFSIANDVAKYFAIIPAIFTLAIPQMEILNVMKLSTSFSAILSALIFNA
                     IIIPCLIPLAMKGVKYRPMKSQAMLMRNMLIFGLGGVIVPFLGIKLIDLLITPLVMVL
                     NLG"
     gene            42554..43180
                     /locus_tag="KR231_001499"
     CDS             42554..43180
                     /locus_tag="KR231_001499"
                     /EC_number="7.2.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="K(+)-transporting ATPase subunit C"
                     /protein_id="HBH0003881.1"
                     /translation="MKTLKPALLVSIVLLVVCGLVYPLVLTGVSQVAFKDKANGSMIE
                     VNGVKVGSELIGQSFTDARFFKGRVSSVNYNTYTKEDLVPDKDGNTSYGGVSSGSFNY
                     GATNPELHDRVQKDIEQFLKDNPTVKREDIPTDLLTASGSGLDPNISPASAKIQIPAI
                     AKASGISESKLQKIVEDNTSKKLFGVLGEDRVNVLKVNVEVAKILGLI"
     gene            43417..44325
                     /gene="cysK"
                     /locus_tag="KR231_001500"
     CDS             43417..44325
                     /gene="cysK"
                     /locus_tag="KR231_001500"
                     /EC_number="2.5.1.47"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine synthase A"
                     /protein_id="HBH0003882.1"
                     /translation="MLYNNALELIGNTPVVRLNNLGCTNGCSNIYVKLEKVNPAGSIK
                     DRAVYEMLEGLEQRGELKKGDVLVEATSGNTGIALSMIGKLKGYEVVIVMPETMSVER
                     RDLMKAYGANLVLTDGKAGMAGSIEKANELLKENPNYKSLKQFENKDNPNAHYKTTAV
                     EIMNDVKDLDIFVCGVGTGGTLIGTARYLKEQNPNIRVIALEPKKSPAISENKTGPHK
                     IQGIGANFVPENYDSSVVDEVILVDDEDAFDTVKLLAAKEGILVGISSGANIFGAIEM
                     AKKYPDKKIVTVAPDGVDKYMSMGIF"
     gene            44352..44942
                     /gene="cysE"
                     /locus_tag="KR231_001501"
     CDS             44352..44942
                     /gene="cysE"
                     /locus_tag="KR231_001501"
                     /EC_number="2.3.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine O-acetyltransferase"
                     /protein_id="HBH0003883.1"
                     /translation="MFKKINKDIEYIMKNDPAARSKIEVFLLYPSVHAMIMHRMAHAL
                     YKKKKLFTARLISQISRFMTGIEIHPGAKMGEGILIDHGMGVVIGETAEVGNRVTIYQ
                     GATLGATGKDTGKRHPTVGDDVLIGAGTKILGPLNIGSNSKIGANSVVVKDVPNGATV
                     VGIPAKIVKIRNLEPVKKNKKEVSYEYDELDNVYYI"
     gene            45102..45290
                     /locus_tag="KR231_001502"
     CDS             45102..45290
                     /locus_tag="KR231_001502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferredoxin"
                     /protein_id="HBH0003884.1"
                     /translation="MKANVNQDTCIGCGLCPSICPEVFDMKDDGKSHVIVDEVPSDAE
                     ESAAEARESCPVDAIDVH"
     gene            complement(45344..46213)
                     /locus_tag="KR231_001503"
     CDS             complement(45344..46213)
                     /locus_tag="KR231_001503"
                     /EC_number="3.4.11.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionyl aminopeptidase"
                     /protein_id="HBH0003885.1"
                     /translation="MKLNRNDSCWCGSTKKYKKCHMDMDNKIDSFAKLGHIVPTHDII
                     KNESQIEEIKKSAVINTKILDYISDKIEIGMSTEDINKLVHDFTLQNGAIPAPLDYNG
                     FPKSVCTSVNNEVCHGIPSKDIILKDGDIINVDVSTIFNGYYSDASRMFMIGNVNENA
                     KKLVQVTKECVQKGLEVAKPWGFLGDIGDVINSYAKKNGYSVVREIGGHGVGLSFHED
                     PFVSYVSKKGTEMLLVPGMIFTIEPMVNEGTHEIFVDEENNWTIYTKDGKLSAQWECM
                     VLVTETGVEILTE"
BASE COUNT        18255 a         4896 c         8125 g        15075 t
ORIGIN      
        1 gatacaacta aaacagaatt aacaagcaac atagaaactg ctaaaacaga gttaaatact
       61 aaaatcgacc aattaatcgc aggtggctca aatgttgcat acactcaaag ggtcgcaatt
      121 gatgattggg ttgaggatgc agaaagtgga ttcaaagcaa ctgtaacaca tagtttatta
      181 acacagagaa tagttgtaaa tattatagat gctactacaa aagaaaatat agttccaaat
      241 tttaaaatag ttgatgataa ttcaattgag attagaagtg aagtaaaagt tgagttaaat
      301 gtctatgtga taaatggaaa tgcagaaact cattttataa atgcaactgt agatgataac
      361 agagtatctg aaatgactac ttattcatct aagaaaatag aggacagatt ggttaatata
      421 gaagaaaagg taaatggtgg tttatctaat attgcaacaa gtgtaaatga gttgataact
      481 tattgttaga gaggagagtg agaaaatgca gactgaatgg aattttaatt atgctaatta
      541 tgtacaaaat gtttcattgc cacctgggcg atataaatta gaatgttggg gtgcttgtgg
      601 tggtgctgtc gatacaagcg attggactga ttgtgcaaaa ggtggttatt caaaaggtga
      661 gattgtattt aaaaaaagaa ctaatctaca aatttgtgtc ggtcaatccg gttatgagaa
      721 agtttctgaa ggttcaagcc ttactagaag tggttttaac ggtgcaggcg ctgctggcaa
      781 agttactact ggtagctttg cttattctaa atacggtggt ggagcaactg atataagact
      841 ttatcatcct agtgcaactt ggggtaacac cgaaagtttg ctttcacgca tacttgttgc
      901 aggcggtgga ggaggtatga aaaataattt tgcttctgct cgttctattg gtcatggtgg
      961 tggttatgta ggtgttaatg gagttggtcg tgacagagat ttttgtggcg gtggttctca
     1021 ataccaaggt ggaacaagtt acgacacaga agaataccat ggttcattag gaaaaggagg
     1081 ttatggtaac ataggaatag gtggtggagg gggttggtac ggtggtgctg gttcttattc
     1141 taatgaatgt ggaggtggtg gaagtggtta cgcactaaat aaagatagtt ataaggtacc
     1201 cggatatata ccaacacctg aatattatct tgaaaatata gtcatgacta ctggaggtaa
     1261 tactactaaa gcagatggtt atgctaaaat aacattacta caagcattgc catttttaac
     1321 agtatcttct tataattcta cacaggcaac atttaaagcc gaccacacag accctgcatt
     1381 acttacaaag atagaatggt ttatagatga tgtactaaaa gaaactataa caacaaattt
     1441 aacagaagag aaaacaatta attatacatt agaagataat gcattacaca cacttaaaat
     1501 agttgttaca gacagtaata atgctacagc agaaaaagtg ttaagtataa gtaagaatat
     1561 aatgccactg cccgaaaatg taaatttaaa tgatatatca acaaaattag ttgaggttaa
     1621 tgcaggattt aaagttggga aaacaagtat tataaacact ttagcactta aaaatataga
     1681 agcaagttta aataatacac ttgtggagtt atcagagaaa ataaaaacaa gttttgatag
     1741 ttcagacact agtgtgcaag atttacaaaa tcaagtaaca caaaaaaaca atactataac
     1801 tcaattagaa acagagttaa gtaaaagaaa aagatttata acaggaactt atacattcac
     1861 aaaaacggat gcagagaatt ttaacttaag tatatatgac aaagaaggaa cttcaaaaac
     1921 tcttactata ccagttaaca tgggcttctc tcctagttta attgtactta gtggagtaac
     1981 ttttagtaca acaagtaaat cttatgttta ttttgataat gtttgtaatt caaattttta
     2041 taattttggc tataattctg attctactca tagtaacccg aaagctgttg gtattcttaa
     2101 tgtatctaat gttgggtatt cttcattagt gcttacatta tataaattat caatgtcaga
     2161 agcagttgga atatgggcaa aagagggagc tacattaact tacaaaatat atatttaata
     2221 aaaaaatgag gtgataatat gaacagaaat aatagaataa tttacgacca aacaggcaat
     2281 atatggcttc aaactggtga agcaacagga gatatacaag agtggtcaaa aataactgaa
     2341 ttaaattttt tggatgttga atttggtagt atagactata gtaaacaata tatagagtct
     2401 ataaatccag ttacaaaaga accaatcatc aaagacatag aagtcatttt aacagatgaa
     2461 caaaagagat tacaagcatt agaaaaagaa ttaagcatgt taaaagaaga aaataaaaat
     2521 agagatagtg agatagtaaa cacagccttt gaggtagaaa atataaaatt aaataacaat
     2581 ttataggagg aattaacatg tataacttat taaaacttat gatagaacaa aagaactata
     2641 gcactaaaga ggatttgcaa cacaaaattg atgtattcta tgcagtaaat agaattacag
     2701 aagaacaata tttagaactt acaagtttat taaataaaga agaaacacca gcagaaccaa
     2761 taaaataggt tcttttttta ttgaaagaag gtgactaaat gacttttaaa gagttagtta
     2821 ataaagttag aaatcttgta ttagaagcaa agaatgtaac tatagaagat acagaaagta
     2881 aatttacaag tgaaaatgta gaaggagcat tgaaagaatg tatagataga gcagatgagg
     2941 cttttcaaga agccgatagt ggaaaaacac ttttatcaac tgctatcggc tctcctgcta
     3001 catcagaaca aacatttcaa gattatgcga actatattac aggatttaag agcaatataa
     3061 gcaatttaga aactcaattg aaaagcaaat attctattag atatggtcct attgatggat
     3121 atgatggtaa tcctttttct gctaattttg gcaagagtgc aagttacctt attgtctatg
     3181 tttactttag aagaagtgta tattattata atcccagtgg tagttcttta ggaagtaata
     3241 caggaggttc tgaacgtgca tggattacta tagacagcaa taaaactggt ttttcagttc
     3301 attcatatga tactagttat gagccatatc cttttacagg ttattatatt gcttgtttcg
     3361 cataataaat tatattatta aaactaggag gatgtatgga agaaattagc ataaatctat
     3421 tatgtgcagt tgcaggagtt gtaatatcct acttagcatt tagaaatagc tcaaacagaa
     3481 agatacaaga tgatacagaa acaactacaa aattagaaca acaaataact tttctgtgtg
     3541 agaatgtaag agatataaag catgatgtag caaagtttaa tacaagtttc ttagatatca
     3601 gtgaacgagt tgcaaaagta gaagcaagta caaaacaagc acatcttaga attgatgaaa
     3661 ttataaatag aattggagga aaataaaaga tggataattt aataagtttt ataccagagc
     3721 agttactaat tttagtagct gctctttatg ttataggagc aggttgcaaa aaatataaac
     3781 aattagataa taaatacatt ccagtagtgt tattgatact tggaataggt ttctcaatat
     3841 ggatgctagg attaaatcct gttgcagtct tacaaggtgt aatttgttgg ggagttgcaa
     3901 taggtgtaaa tcaaacttac aaacagttta aggatggtga aaagtaatga aattaacaaa
     3961 aatattatta ctcacaaaaa tttaaaaaat ttcattaaat agagtatact tttatagcta
     4021 ataagtatat aataatagta cagaactcgt aaagcattta tatgctcaaa tatacgggac
     4081 attgattttt gaaggaaccc gccaagcttc ttttatagct caaatagtcg ggacagataa
     4141 atttacccac taatattaat tggtgggttt tattatataa aagtatatct atgaaaaggt
     4201 gaaaacaatg gttgaagtaa aagaagaaaa aacatttgat gaacaaatag atattttaaa
     4261 aagtagagga ttaataataa atgataaaga agatgctaaa tttgtattaa gtaatgtcaa
     4321 ttattatagg tttacagcat atcttctaag ttttaagaat gatgatggct catataaaga
     4381 aggaactacg tttgaagaag tttatgatat atataggttt aataaggaat ttaggatatt
     4441 attaacagat ttgttaggga gcatagaaat agcatttagg acatacattg catatacatt
     4501 agcaattaaa catggtgctt gtggatatct ataaagggag agtttcaaag atgaaaaatt
     4561 ctatattaat tttttgacag cattagagag agaaaaaaat aataattcag ataagctttt
     4621 tattatacac cataaagaaa aatataaagg aaaacttccc atttgggttg caacggaaat
     4681 aatgactttt ggtatgttgt aaaaattata ttcaaacatg ttgccagaag atactagata
     4741 cataaaaaat aatttgtgta gagtgaatac tttattagtt aaatcttggt tacaatcatt
     4801 aacacaggtc agaaatcaat gcgctcatta tggtagaata tataataata atttccgtat
     4861 tataacaata aaaaacgaat ataaaaagta taacttggat aataaaaaga tattttctta
     4921 tatacttgct atgaagcatt tgactatgga taaattaatt tggaatagtt tttttataaa
     4981 acttcaaaag ttaattaatg attataataa ttctatagac ttaaagctta ttggttttcc
     5041 taataattgg atagagatat tggctaaata aaatagttac tttaagaagt ttataaacac
     5101 ttactatatg taagtgtttt tttattgaaa agaaggagga aaataaataa tgaaaatatg
     5161 tattacagta ggacacagta ttttaaaaag tggtgcatgc acttctgctg atggagtagt
     5221 taacgaatac caatacaata aatctcttgc accagtatta gcagatacat ttagaaaaga
     5281 aggtcataag gcagatgtaa taatatgccc tgaaaagcag tttaaaacta aagcagaaga
     5341 aaagacttat aaaataccta gagttaatag tggaggatat gatttactta tagaactaca
     5401 tctaaatgca agtgatggtc aaggaaaagg ttcagaagtt ctatattata gtaataaagg
     5461 tttagaatat gcaactagaa tatgtaataa gctaggtaca gtatttagaa atagaagagc
     5521 taaattagat aaaggattat atatcttaaa tagttcaaat cctacagcag tattaattga
     5581 aagtttcttc tgtgataata aagaagatta tgagaaagct aagaaactag gtcatgaagg
     5641 tattgctaag ttaattgtag aaggtgtatt aaataaaaat ataaataatg agggagttaa
     5701 acagatgtac aaacatacaa ttgtttatga tggagaagtt gacaaaatct ctgcaactgt
     5761 agttggttgg ggttataatg atgggaaaat actgatatgt gatataaaag attacgtgcc
     5821 aggtcagacg caaaatcttt atgtcattgg tggtgcagca tgtgagaaga ttggttctat
     5881 gactaaagaa aaatttacta tgataaaggg taatgataga tttgatacac tttataaggc
     5941 attagatttt attaatagat agattatata aaatatttta gtatttcttg aaaatcataa
     6001 gtatggtaat atttagataa atattattta ttattaatag gtatgggggt agattatgat
     6061 atttaagaag tatataaaat cattactgat agttgttagt gttacattga taatgaacaa
     6121 atcaatatta tttgtaaatg cattagattt agagagtaac aataacataa aatcttataa
     6181 aagaaagaat gtaaaggaaa ttgatataag caataaattt gttgatgaat cctttagaag
     6241 agatattgtt gaaaaggtat tagataatag ggatgatcca ttaacaaatg aagttgcatc
     6301 aaaagataac tataaaatat atgaaagtga tttaaataaa attgagagtt gcttagagtt
     6361 agatttacat aaaaatccag atgtttccaa cccaaacaaa atagataatt tagatgggat
     6421 agaaaatttt agaaatctag aaaagcttga ttgtagttca aataatctag aaagtgtaga
     6481 tttaagtaaa aatataaaat taaaatatct agatattagt ggaaataaaa tattaaacat
     6541 taatttaaaa aacaataatc ttattaatga attacattgt gatgcaaata aattatcaag
     6601 tttagacctt aaaaataata aaaatttggt aagtttattt tttactagta atgaattaac
     6661 agagatagat ttaagtaata atgtgaactt agaaaatttg caatttctta ataataattt
     6721 aaaaagtata gatttaagtc ataataaaaa gttgaaatct ctaaattgta ctaacaataa
     6781 acttaaatct cttaatttaa gtaataatgt ttttttgaaa aatttaagtt gttcaggtaa
     6841 taacctaagt aaattaaata taaaaggact tacaagtctt gagtatttgg gatgtgctaa
     6901 gaataaatta caagatttag atgtatctac aaatataaaa ttagattctt tattttgtgg
     6961 gaaaaatagt ttaacaaaaa tagatataag taaaaataaa gaattaaaat cattggaatg
     7021 tagtggtcaa tatatagaaa aaagtattat aaaaaatggt gaaaatatag ttgtagatat
     7081 aggaattgaa aattcgaaat taaaggaatt atatccacaa aattataata tctcaacagg
     7141 ttttctaaca tggaaaaata tttctgaatt tccaaataac gtaagttata gtttggaata
     7201 tgaatatggt ccagtaaatg atgtagagac tatggatgta aatatatcaa tagataaatt
     7261 agttaaatgt agaatcagat atatagatta tgatggaagt ataatcaatg aaaaagaaat
     7321 atcagataat tctagtataa atgaaattca aattaatcct caaagagaaa actatgagtt
     7381 taatggttgg agaaacaata aagatgaaaa aatatataca tcagagcagg taagtaaatt
     7441 agtttttgat gatagtactg attttatagc aacttataaa agaaaatcaa caggatcaag
     7501 tggttcttct ggtggaactt caagtaaaga agattttaat atagcaccat ctaaggaaaa
     7561 attaacaggt gcagacagaa atgaaacatc agtgaaaata agtcaaaaag gatggaataa
     7621 agctgataat atagtgttaa taaatgactc tagcatatcg gatgctttat cagcaacacc
     7681 atttgctaag tctaaagatg caccaatatt acttactaaa aataataact taaataaatt
     7741 aacagaaaaa gaaataaata gattagaagc aaaaaatgtg tacatagtgg gtggattaaa
     7801 gtctgttgat gaaaaagtag tgtctgattt aaagaaaaaa ggattaaatg taattagaat
     7861 atctggaaat gatagatatg aaacatcaat aaaacttgca aaagaattag acaaaaattc
     7921 taacctgtca aaagtagtag tggtaaatgg agaaaaggga ctagctgatg cagtaagtat
     7981 gggagctata tcagcaaaag aggaaatgcc aattcttctt actaatcaaa atgatgatat
     8041 gaaagatata aaagacttaa tagctaataa aaacatatca aaatcatatg taataggtgg
     8101 agaatcttta tttaataata aagaagtgaa taacacatta ccatctgtaa ctaaaatagc
     8161 aggttctgat agaacagaaa ctaactcaaa agtaataagt catttctata gcaaagatac
     8221 acttaatgac ttatatgtag ctaagaatgg aatgaataaa caagacgatt tagtagatgc
     8281 cttatcagta ggagtgcttg caggtaaaac tgaatctcca gtagtattag ttggaaatgg
     8341 attagatgat agccaaaaag agttaatcaa gaataaaaag tttaaaaata taactcaaat
     8401 tggtggaaat ggaaatgaaa aagcatttaa tgaagtagaa aacttagtta aatagattga
     8461 aaggtagtaa ctggaaatag ttactacctc cttttttatt cattttcagt tttttcaata
     8521 attatttttc catcctcaaa agtaacaaga acatcccttt catcaggaga gatattcatc
     8581 tctttaatcc atgacattgg aagtatcaat ctgggtgtaa aagagccttt gccactttta
     8641 ttgaatgcaa ctctaagttt tctttgttcc aataatatca ttcctttcta ctattaataa
     8701 atgccagcaa taataaagta aataccaaag caataagagc tttaaaagta aaacttatta
     8761 ttatattaat aatatttaaa actatagtga taccaagaat aatcatacaa attctataaa
     8821 atttattatt catattaaat tagaaaatgt gttataatat tagaaagaag ctacctagaa
     8881 ggaaggtatt ttcctcctag gattgaaact tataattctt taatcaatct tagtattgcg
     8941 agtactagat taattaaaac taatgtgaaa gagaaagcat ttttaatttt attaaatttg
     9001 ttttctcttt tattttttct tctttctaat ctccccactt tctttgtcct cccttctaag
     9061 ttttttattt tcttacctcc tttctatatt tatattatat catcacgtga cgtgaaagtc
     9121 aataaatatt ccatattttt caataaagct ataaaatata ttaatataaa atacaaaata
     9181 taataaaaat aagtggatgt ttacattata cacccactta ttttagagtt attcctcatc
     9241 agattttttt attataatct catcttcctt aaaaataact acagccttac gtttttccct
     9301 tgtaaatccc attttttcaa gttggcttaa aggtaaagaa attttagccg aataagtacc
     9361 tgaaccacct ttactgtaaa ctattttaga ttctttttgc tccaaactat tttcctcctt
     9421 ttttatattg taatgtaaca aatattaaca ataaaatgct tactattaat cctattatat
     9481 tgttgatatt aaaatgtaaa aataaaagta ttatgtctat tactatagtt atagcaacta
     9541 taataagaca gaatttataa actttatcac tcatatttta tagaaaatgt gttataatat
     9601 ttagaaagaa gtcactagga agaagattaa attcttccta gcttacaaaa ctataaatct
     9661 tttaataatt taattagttt atcaattaaa tttattaaaa tgggtaagat agagagagca
     9721 gttttaactt tggcgagttt gctttctcta tctttttttc ttctttctat tctactcatt
     9781 ttccttttca ccccctttct atatttatat tataatatgc cgaaccggca aaagcgatat
     9841 ttatttccat atttttcaat aaagttatat tgacaaacta tattttttta caaataaaaa
     9901 taagggtggc aaaaccaaac ttgccaccct tttgccaccg aaaataaata atagaataaa
     9961 tttaaattaa acataataaa acataaacaa caaaactgac cttaataaaa cattgaaata
    10021 ccaacacttg taaaaaataa caacaataaa caaataacct agaataatat tacaacttaa
    10081 gtaaataata attttgaata ataatttacg gaggtattca tatgtttaaa cacgataaag
    10141 cattattaaa agaagtaaaa gtagaaagac caaatcctca atatgctgtt ttaatgcaag
    10201 aacagttggg tggtgcaaat ggagagttaa aagcagctat gcaatacttg tcccaaagtt
    10261 ttagaataaa agaccctcaa ataaaagatt tatttcttga tatagcagca gaagagctta
    10321 gccatatgga aatggtagca caaactataa atttattaaa tggacatgat gttgattata
    10381 attcagttaa tacaggcgaa atagaaacac atgtattaac tggtctatca ccagtcttaa
    10441 taaactcatc aggagctcct tggactgcta attacgttac agttacaggg gatttagtag
    10501 ctgacttact ttcaaatata gcttctgaac aaagagctaa ggtagtttat gagtacttgt
    10561 atagacaaat agatgataaa tatgtaaaag aaacaataga tttcttactt aatagagaag
    10621 aagcacataa tgctctattt agagatgctt taaataaagt taaagataca ggttcaaata
    10681 gagattttgg agttacagaa gattctaaat tatatttcga tttgtctact ccagggccaa
    10741 atcacgatac taagatagat attaatcctc cttcttttga aaaaccttta aaaaaataat
    10801 ttgatatttt ttatgttgtt ttgttttagt agttataaaa attatttact aggagaatta
    10861 attatatgaa aaattaaata tgtatggtta aaaatgggta tacacttatt ataagtgtat
    10921 atctatttgt ttattgcaaa acatataata aaataacaaa tgaggtggta ttttggacag
    10981 taatagaaaa cctaataatc taataaatga aaaatctcca tatcttttac agcatgcata
    11041 taatcctata aactggtata gttggaatga tgaggctttt aaaaaagcaa aagaagagga
    11101 taagccaata tttttaagtg taggatattc aacatgtcat tggtgccatg ttatggaaaa
    11161 agaatctttt gaagatgaag aagttgctga aataatgaat agaaactttg tggcgataaa
    11221 agtagataaa gaggaaagac ctgatgtaga tagcgtgtat atgacagttt gccaagccat
    11281 gacaggtagt ggtggatggc caatgaccat aataatgaca ccagataaaa aacctttttt
    11341 tgcgggaaca tatttcccaa aatattcaag gtataataga cctggagtta tagatttatt
    11401 agagaatgta tctgaaaagt ggaatacaag cagggatata ttaataaaat ctggagatga
    11461 aataatagaa gctcttaagg atgattttgg tgtaaaaaat actgagggtg atttatcaaa
    11521 agagatgttg agttcatcag ttagagtatt taaggctatt tatgatgaaa agtatggtgg
    11581 ttttggtaat gctcctaaat ttccaagtcc tcagaatctt atgtttttaa tgaaatatta
    11641 tagtatagaa aaagacaaag atgtgttaaa aatggtggaa aaaactttag atggaatgta
    11701 tagaggaggc ttgtttgatc atattggatt tgggttttca agatactcta ctgataaaaa
    11761 gtggttggct cctcattttg aaaaaatgct atatgataat gctatgctta ctatagcttt
    11821 tttagatgcg tataaaataa caaagaaaga gttatataaa gaaattgcta taaaaactat
    11881 agattatgta gttagagaga tgaaggataa agaaggtggg ttttattcag cacaggatgc
    11941 tgatagtgaa ggtgaagaag gtaaatttta tacatttaat cctcttgaga taattgaagt
    12001 tttgggtgaa gaagatggaa ttttctttaa taattatttt gatataacta gtagtggaaa
    12061 ttttgaaggc aaaagtattc ctaatcttat aaaaaataaa gaatatgaga gacataatga
    12121 aaagatagct gaccttagta aaaaggtatt tgaatataga aaagaaagaa catctttgca
    12181 taaagatgac aagatactta catcatggaa tgcattgatg atagttgctt taacaaaggc
    12241 atatagtact ttaaaaaatg acatatattt agagtattca aataagtgtc ttaactttat
    12301 aaataataat cttgtaaatg agtcaggtag attattagct agatatagag atggaagttc
    12361 cgactattta gcatatttag atgattatgc ttttttaatc tgggcgtata tagagcttta
    12421 tgagtcaaca tttaatatga aatatttaga aaaggcttta aatttgaatg aaagctgtat
    12481 caaccttttt tgggattatg aaaaaagtgg attttatata tatggtaaag atagtgaaaa
    12541 tttaatagca agaccaaaag atttgtatga tggagctatt ccatcaggaa attctgttca
    12601 attatacaat cttataagac ttgcgaaaat tactggagat aatagacttg aagaaatgtc
    12661 atataaacaa ttaaaactgt atgtggataa tgtaaagagt tctccaactg gctacagctt
    12721 ttatatgctt tcattgatgt ttgaacttta ttctactaag gaaattatat gtatttttaa
    12781 ggaagattct gatttaattg catttaaaga attgataagt gaaaatttta taccaaatgc
    12841 aactttttta gcaaagaaat acaatgaaga aaacactatt ataggttttt taaataacta
    12901 tatattgaag gatgataaga ctagttatta cgtgtgtcaa agtaatagtt gtagtcaacc
    12961 aattaatgat ttacaaaaat taaaagatat gattttagga gtagaataat cataatagcg
    13021 aaaaaggaga tgctttaaaa taaaagtcta atcatctcct ttttttgtat aaaaaacaga
    13081 aaaagagttc ctaagaacac ctaatctatg taatgattgt tttgttaaaa aataaaaatg
    13141 acattatagt tatataaaat attgtactat aaaaaagtgg tattatagat gcgatagtat
    13201 taatcttttt tatttaccct atttcttctt tttgcaaatt cttcaagtgc ttcagattta
    13261 attttatcta tttcttcata ttccataaaa ttagcatctt cttcaaagcc atcttgttct
    13321 tcaccattaa aacgatacat tttttttagt aaactccata aggtctctaa ttcatctttg
    13381 gtaaattcgt gaaatacatc tgccataaag tttattccag tcctactaca tgttaccata
    13441 accttttttc ctaagtctgt aactttaaca ttaattgctc tcttatcatg aggacttgga
    13501 attacatcaa catatccatt tttttcaaga ttagcaacta gtctatttat attttgttta
    13561 cttgtaccca tttttcttgc aatattattt aatgttgttt cttcctctgg taaatgaaga
    13621 attgataaaa tagtcatata ctgtcttgaa gtaagtatac caaaatattt atctccttct
    13681 atttgtattt tgtttgtaag ggtaaaaaga gttgcatatg tttgattcat taaaaagagc
    13741 tcttttagtt catttgaata atccatgaaa tatatctcct ttatttttag atgttgtttt
    13801 gtcgaaaaca gaatatcatg aattaattct aatgtcaata tggtgtcaaa atatattaaa
    13861 gtattacttt tttatgtaac tattaattaa ttaaattatt gtataatttt atgtaaaaac
    13921 ttctatgtac caatgataat ttctatgagg aattaataat tcttaaattt tttagaaaga
    13981 ttttgacttg aaaatacttg taatataata tataaattaa tatactgaat aaaatcaatc
    14041 tggagggata attatgaagt gtacaaactt tactttcaaa ggagaggaag gtttagatat
    14101 atatacatat aaatgggaag atgaaaatat aaaaaaacca aaggcagtta tccaaattgc
    14161 acatggaatg gctgaaactg cacaaaggta tgagactttt gccaaggtac ttactaaaaa
    14221 tggttatata gtatatatca atgaccatag aggtcatgga aaaactgcaa agataataga
    14281 aaatgttgga catttagctg aaaaagaagg atttagatgt cttgtagagg acatgtatac
    14341 tttaacaaat attataaaga aagaaaatga agatttgcca atttatctat ttggacacag
    14401 catgggttca tttgcaagtc aaagatatat aatggattac agtaataatt tatctggtct
    14461 tatactatgt ggttcaaatg gaaagcaagg aatcattcta aatcttgctc atctgataat
    14521 caatcgtgag attaaaaagt atggaagacg ttctaaaagt aataaaataa ataatttgat
    14581 atttggtggc gaaataataa gaagaaatga aaagactaag tttgactggt taagtagaga
    14641 taaagaacaa gttgaaaaat atataaatga cccattttgt ggagtagtgt gtagttgtgg
    14701 ctttttttat gatttagttc aagggttaaa agaaattgag gataaagaaa acttaaaaaa
    14761 agtgccactt gatataccta tttacataat atctggagat aaagacccca taggaaaaaa
    14821 tggtaaagga gtcttaagac taagggatag atatataaaa ttaggagtaa aagatgtaac
    14881 ttgcaaactt tacaaagatg gaaggcatga attgttgaat gaaataaata gagaagaagt
    14941 ttttgaggat ataatttgtt ggttaaataa taaaatagaa atattgtaat aaaaaaatat
    15001 aatgatatat ttgctttaaa tttatttata tataatattt gaaaagtgga ttatgtatat
    15061 gcaaagtaga aaagagagag cctagaagtg attttttgct ataatgccat ttattgaata
    15121 ggtgggtgtt attataaata aattattaac actcagtatg attatcattg tatatggaat
    15181 ttattttatt taaaattcct tgaaagttta aatatagtaa gttgtaataa agagaaaatc
    15241 taaatattta aatgctattt aatgtgaatc tattaattag gttatactta aacttaatta
    15301 atagatttta tatttcaagc caatgagata gggttttaga ttaaaatata accaatggtt
    15361 aaattacaga cattttgtta actttccctc gatttactag taaatatttt ttttatatac
    15421 ttaaattaca acagatgtac tagggaggta tatatgcaaa ttaaaatagg taaagtcata
    15481 cagtgtctta gaaaagaacg aaatttaact caagaacaat tagcaaagtt tataggtgtg
    15541 tcaacaccag cagtatctaa gtgggagagt ggaaattctt acccagatat agaattattg
    15601 cctttattag cagacttttt taatgtgtct attgataagc ttttaaatta caagattgat
    15661 ttaagtgaag aagaagtaat gaaaatttat aaagaattag aatcaggctt tgctagaatt
    15721 gaaattgatt tatcaacaga agaaccaaaa gaagaattta gacaagactt agaatctgta
    15781 aaaaagcttt ccaatatgta tatagagaag tatcctaaaa gctatttatt gaagctaagg
    15841 atatgttcgc tgtatcagat gtattcatat aaatttggta agagtgaact taatgacaga
    15901 gtaaaagaaa caatgaatat tcttgaagat atagtgagaa atacagatga tatccaaata
    15961 aaagaaacag ctcttattat attatcaaac gcatattgta tgttggagga ttatgaaaag
    16021 gcagagttgt atttaaatat gatacataag tcaatagggg atacaagtgt taatttagct
    16081 atgatatatt taaagcaaaa tagacttgaa gaagcagaaa tattgcttca aaataaattg
    16141 tttagtaatg tatttaatat aagcatggat tgtaagggaa taattaatgt atacaaaaat
    16201 caatacaagg aattaaagaa aaaattggag aatagaaatt ttaataaaaa tgcaattgag
    16261 agagaaatgg agtatataaa aaataagttg ctggggtatg caaatctttc tttagaaata
    16321 aaaaaaatgc tcagtgaaga taaaggtgca ttttttagta tgtatatgga ttatatggaa
    16381 ttatctctaa tttttttatt ttttaacatg aaagaagaag caaaaaaagc cttatatagt
    16441 ctaaaagaaa tattagaaaa atatcctata catgaaagtt tggatgtaag tcaaatgaga
    16501 ttttttgata aggtagagtc taaaaattta tatactttta atatatatac aaacttgtta
    16561 attgtactta atgatgatag ttataatgag cttagagaag aaccaatttt taaggatgta
    16621 attgaaaaga ttttagatat ggaaaaaatg ttgaaaaata aagaataagt aaaaatttaa
    16681 tataggactt aaagattaat caaattaaaa gaaagtgttt caaaataaaa atttgaatca
    16741 ccttttttgt cggtcttaaa cagttattta gaaaaataga ggtttcaaaa tagaaatctg
    16801 aattatctgt attattacac aaaaatagaa acctaaattt ataaaaatag aataaagttt
    16861 gttatataaa atgtaatttt gtctataaaa tctcacttgt tttcttaact ttaagcgtga
    16921 aaaagagaat gtatcatgaa ttttttagtt catgatgcat ccttctttgt atgaaatcca
    16981 atatatcttt attatttaaa caatggaaaa gagccttatt tctattttga gacatctctt
    17041 ttatttaatt atgaagtttt atacagttca ataaatagga attatattta gaaactcatg
    17101 acattatttc ttagatagtg attaaattta tcatattcca ttttagataa cttttctggg
    17161 taagacatta caatcaggtt atgcccatta aatttttcat ggtatggtgg atgaatgtgt
    17221 tcataattat ttgtcttata ttttactctt tcatagaacg ccttgcgata aattgaaatc
    17281 tcatcaattg gaaggtcaat ttctaaaata atagtttttc ctttcttatt taaaagctct
    17341 aacgctcttt gtccatatct attattgcgc atttctggaa aaatgcagaa atgttctaca
    17401 tagataaagt catctgtttc ccaacataaa attatgccga caaactggtt tttatcataa
    17461 attaaattga actgatattc tttatttttc aaaatttctt cttgcaaaga agattttctt
    17521 tgttcatgaa atgggaaact aattttatat aattccatag ccttgtaaca taatttattt
    17581 tcactggttc ttaaccgttt aaatttcact ttactcctcc taatcacgaa aattccaatt
    17641 tatttatgag ttcattttac catagtcagt atttgcatac aatgtgtttt aagttgagtg
    17701 tcatttcttt cttttattta tgcttatatc tcatagacta agagataatt gcttaagaca
    17761 taactaaaaa ctattatatt aagctttgat aatctaaaaa cagtatattt atggactttt
    17821 ctaggtctaa aagtaatctt aataatttta gaagttacaa aaaagttaca taaatttgga
    17881 aagctataat atacatatat aatataaggt taaaactgta atgaataata ttaatttaaa
    17941 atttgaacat ggaaggagat tattatggag aaaagagaaa agaggataat aatatcatct
    18001 ttattaagtg tatcaatttt aatgggtttg gtaagtatat attctatatt aaataaagaa
    18061 gacataattt taactgttaa gggtcaagag caaaaagtat cttcctttaa gaaaacagtt
    18121 gaggaacttt tggatgaaca gggtataaag tataattctg aagataagat taatccaagt
    18181 ttagatacag aactaaaaga tgatatgaaa ataaaagttg ttaaggtaac taaaagtaaa
    18241 aaagaagaga ttgaaaaaat tccatttgat acaaagcatg taaatgatag taatttgtta
    18301 aaaggaaaat ctaaagttta tcaagaaggt caagaaggag aaaaaaaact agtctataat
    18361 ttaacttacc atgatggaaa gttagtcaaa aaagtcttat caaaagaagt aatatctaag
    18421 gagccaacta caaaaattat aaaatatgga actaaagaaa aagtactaat agcatcaaga
    18481 ggagcaaata taagaggagg caaacatatg aaagtggttg ccactgcata tgcaggagat
    18541 acaataacat ctactggtac aactccaaga tggggtgtta ttgcagttga cccacgtgta
    18601 ataccatatg gaacaaaagt atatatacct aaactgggta tgacttttgt agcagaagat
    18661 tgtggaggtg caattaaagg taatagaata gacattttta tgaacagtga aggaaaagct
    18721 tcaaattggg gaaggaaaag tatagatata tatctacatt aaattagtga atagaataac
    18781 tttacttgaa ggacaaaaaa gtataaaata tgaattaact aaactgttag attattctta
    18841 aaacataaaa atatatctaa ggggggataa gatgaaaata gtatgcttag gagacagttt
    18901 aacgtatgga tttggagtat cacgaagtaa ttcatggaca aacattgtaa ataaagagac
    18961 tcgattagaa atagtaaata agggtataaa tggtgataca acaagtggta tgttagctag
    19021 gtttaatgaa gatgttgtaa aaaattctcc tgatatagtt tttataatgg gtggcaccaa
    19081 tgattttatt gctggtgcgg gaaatgaaat tattaattct aatataatgg ctatggtgca
    19141 tcagtcatat tcaaaaaata ttatacctat aataggtata ccattaaaac cagatattcc
    19201 aaatgttagg gaagattgga gttgttttac tgattttaat atagtatctc aaaacttaga
    19261 atcatatagt tattggataa aaaaattttg tatgacattt aatactaatt tcgtagattt
    19321 ttattcagaa tataataaaa atatggaact agaaggatat aaaaaattat attttgatgg
    19381 gttacatcca accaaagagg gtcatagaat aatggcagac atttttatta attcaattaa
    19441 taagtatata gaagagttat agattacatt aaaatgcttg tttatgcgtc agttgcaata
    19501 aatacataca gtagagaggg gtttattatg gattatacta aaacttatga agagtggata
    19561 aagggttcat attttgatga agatacaaag ctagagttgg agaatataaa aaataatgaa
    19621 aaagaaatag aggatagatt ctataaggat ttagaatttg ggactgcggg tcttagagga
    19681 ataattgaag caggaacgaa tagaataaat aagtacacag ttagaagagc tacttttgga
    19741 ttggcaaact atatattaga aaacacaaca aaagaagaaa caagtagagg agtagtaata
    19801 gctcatgata atagacacaa gtctagacaa ttctgtatag aatctgcaaa tactttggca
    19861 gcatgtggta taaaagcata tatatttgat agtttgagaa ctactccaga attatctttt
    19921 gctgttagaa gcttaaatgc aatcgctggt atagtcataa cagcaagcca taatcctcca
    19981 gaatataatg gatataaggt atactgggaa gatggagcac aagttatgcc agagattgca
    20041 aatgcaataa cagagaaagt aaatagtata catgattata gtacaatacc aaccttaacg
    20101 gaagctaata aaaatttggt agttttgttg gacgaatcac aagatactaa atttatagaa
    20161 gcagtgaaaa gccaaattat aagaaaagat ttagttaaaa atgtaggtaa aagctttaag
    20221 atagtttata cacctctttg tggaacaggg aatgttccaa taagaagagc attgaaagaa
    20281 gttggttttg aaaatataat tgtagttcca gaagaagaaa atccagaccc aaattttgca
    20341 gggcttgatt atccaaatcc agaagagaaa aaagctttaa atagaggtat attactcgca
    20401 aaagaaaaag gagcagacct tgtaatagca actgacccag attgtgatag agtaggtgta
    20461 gcagtaaaaa ctactacagg tgagtatgct ttacttacag gaaatcaaat tggtggtatg
    20521 ctgacacatt atataataga aggattaaaa gaaaataata aattaaaaga aaatcctaca
    20581 ataataaaaa ccatagttac atcagaattt ggagcagata tagctaaagc aaataatgtt
    20641 gatgtattaa atgttcttac aggttttaaa tttattggtg aaaaaataaa attatttgaa
    20701 caaaataaaa atagaagtta tgtatttgga tatgaagaaa gttatggtta cttagttggg
    20761 actcatgcta gagataaaga tggtgtagtt tcttcattgt taatatctga aatggcagca
    20821 ttttactatt caaaaggtat gagtttatat gatggtttaa tagaacttta taaaaagtat
    20881 ggatttttca aagaacagac tatatctttg actttaaaag gtatagaagg tgtagaaaag
    20941 ataaaagaaa taatatctta ttttagagaa aatcaaattg attatataaa tagtattaaa
    21001 gtagttgata aaaaagatta taaaaatggt atagataatc ttcctaaatc tgatgtttta
    21061 aaatactttt tggaagatga atcttgggta gctataagac catctggaac agaaccaaaa
    21121 cttaaatttt acatagctgt aaaaggagct agtgatattg aagcagataa aaagattcaa
    21181 ggtttgaaaa agtatataga tgacatggtc gaaaaattaa aataaaatat tattatttta
    21241 taagataatt ttgtaataat atttatttag ctgaaaatta taatttactt tcattgagta
    21301 gaatatggaa atgttagtag aattgttatt ttcagctttt atttgtgtta tttttactta
    21361 aataattata ttatagaatg aatctgagta taattaatat tgtataatga aattaatttg
    21421 atagaaaagg ggatatttat gtttggtata gataagaaat tgattgaata tataattgca
    21481 aaatccaatt acagtgaatt aagttcaaag tcagcagaag tatctttctt cttaatgttg
    21541 tccatatttc cttttttaat atttacaata agttctatag cttatatacc gattcttcat
    21601 ttaaataagt atatagcttt gtttagaaat atgatgccag aaggtgcttt tgctgtgtta
    21661 tcttcaatca tagtttctgc aatagacaat agaaacctga aatttttagc agtcagtttt
    21721 gtacttacta tgtggacatt ttcaagagca gtaaaagctc ttattaaagg aatgaataga
    21781 gcctataaag ttaaagaaac taggtctttt tttaaaattt tatctatatc atttttattt
    21841 acaataatgc ttttggtcct tattttttta tctatgatat ttttagttta cggtgaaaaa
    21901 ataggttatt ttatttttaa tcttgtagga ttggatgaga tatttataaa aatatgggat
    21961 attctaagat acactgtagg tataataaca ataatagtga tatttacact tttatataaa
    22021 tacactccaa ataaaaagtt aactattaaa gaatctgcgc caggtgctat ttttgctact
    22081 tttgcttggt ttttagtatc atttttatat tcttattata caaattacta tgctaactat
    22141 gaagtaatct atggaagtat agctgaaata attgtactta tgacctggat gtattttagt
    22201 agttggtcta tcgttattgg ctatgaggta aattcaagat tgtattttag aaagataaga
    22261 catgaaatgt taaagtaaag tatttaaaat aaaagagagt atttagtatt ataaatgtaa
    22321 ttgaattaat aaagaaatat tgacatttaa gttaaaaagt ctagaatttt tctgggcttt
    22381 ttttattttt agtataactt gacaaatttt atttaatggg atagttttaa tttataatca
    22441 tctttaaaaa gatgactatt gataagtaag agataaaatt ggtaagtatc aaaaaatata
    22501 ctaaataaaa attatagtcc taatgagtta atttctgtat tttcaaataa tgcagtattt
    22561 agtcatgtgt ttttatatgc gcctgtattt ctaattagca atatattaga ataagctact
    22621 gtaattagat ttagaaaaaa gcgacataaa taattataaa caaataataa attacataaa
    22681 attaaattta ttcacaagta tatcttataa aatatgttat aattaataga aaattgtcat
    22741 ataattaatt aagtagtatt attataaata acattgaaag gtagtggtta gaatatggat
    22801 acccataata aatatgtaaa ttttataaaa aatatacctg tacctttttt atattgtaga
    22861 attgtaaaga gacaagaaga tatagaatat cgagtagaat atataagtaa gggtatgggc
    22921 aaagtattac aattagaaga aggtatttgt gataaaaata tactagatgt attgcctgta
    22981 tttaagtcta aaaaatattt caaagagttg ttctcaaatg aagtggattg tataaaaagg
    23041 tacattccga cacttaaaaa ctggataaat ataaaaaaac agataatagg ggattcatac
    23101 ataattttgt attttggtaa aattgtattt gattatagac agataatcga ttcctttgat
    23161 aaaaaggaaa aagtagctta tattaaagac gaagaaggca tatatataga ttgtagtgaa
    23221 aatttaatac caatattaaa taacaacatt aaaacaacga aagatatctt tggtaaaaat
    23281 gatatagaag tatggggaga gaatacagga aaattattta gagatgatta tagagaagga
    23341 gtatctagta aaaaaagatt tttacaaaat ctttttgaat atgaagaaac attttttatg
    23401 gttgaaaaat attttttgta tgatgaagac gaacttttag gtactatagg gatagtagac
    23461 aatataatat atagtggtta cagtaataga aattataact caaaagattt aatgaagatg
    23521 atagaacact caattccaga gaatatgttt tataaagatg tgtatggaaa ttatattgga
    23581 tttaattcag gttttttgaa tttagcttgt atgaataaag aagaattatt agggaagaat
    23641 agttataaaa tatcagaaga agaagcttta atagataaga tatttgaaag tgataagggt
    23701 gtagttgaaa ataaaaaagt agttacattt gagttaaata taagtatgaa tgatgaaaac
    23761 aagtgtattg agattacaaa aaggccgttt tttgatagct atggaagtgt tattggaata
    23821 attggaacag caagggatat aagtagaaga aaaagattag aagaggaaat ggataaaact
    23881 aggatggaat tttttgcaaa tttatcccat gaacttagaa cgcctataaa tttaatatca
    23941 tcttcattac aagtgataga aaaaaaagaa gcagatttaa tagaatcaaa tgatacttta
    24001 aaaagaaatc taggtataat aaaacaaaat ggaaatagaa tattgaggtt agtaaataat
    24061 gttatagact ttacaaaaat gcaatcagga tatttagatt ttaaaccaga agaatctgat
    24121 ataattgcat ttatagagga gatatgtatg tctgtagctg attttgcaag ccaaaataat
    24181 atacaactta catttgatac agaaatagaa gaattttcaa tgttatttga ttcagaaaaa
    24241 ttggaaagaa taatattaaa tttactttct aatggaatta agtacaataa gaaagatgga
    24301 aaaataaata tatttttata tgtgaaagat aatgtattta atatgaaaat atctgatagt
    24361 ggtataggta taccaaaaga aaaaatagat aaaatattta ataggtttga acagattgac
    24421 aatgaacttt cttacagagt taaaggaagt ggtattggac tttcattagt gaaatctttg
    24481 gttgagttgc atgagggaag tatatcttta aaaagtcaac ttggtattgg aagtgaattt
    24541 atagtttcat tgcctgttag aagtaaaaat aatattgaaa aatataatca taaaagagaa
    24601 atcagcaatg aactaagtaa aaaattagaa atagagttct cggatttata agtttaaata
    24661 taaaaaataa aattttaaaa aagtattgac aattgattta gaagggttta aaataaatta
    24721 caacataata aataaaaagg cgatgaatag gaagagtaaa tctaattcga ttaccagaga
    24781 gaagagtccg ttggctggaa gactttttaa attagaggga ttgaaaacta cctaggagct
    24841 actttctgaa gtcatctgca ttagtagatt ttagtaagaa tagtcgttag ctgcgttaaa
    24901 gtgtaaagtg agttttcatg acatatgaaa actaaattag gtggaaccgc gggaataata
    24961 ctctcgtcct tatgttataa ggatgagagt tttttgttat ttaaaaatat aaacagtaat
    25021 cataataatt atagaaaata taaaagcaat gaataggaag agtaaattta attcgactat
    25081 cagagaggaa agttcacagg ctgaaagact ttctaagttt gagaaattga aaactaccta
    25141 ggagctgtgg tctgaagtta ctttaaaaag ttttagtaag actaaccgtt aactgcgtta
    25201 aagtgtaaag tggattttat caataaatga taaaatcaaa ttgggtggaa ccgcgagtat
    25261 agactcgtcc ctttatatag ggatgagtct atttttattg caataaaaga ttgaaaataa
    25321 aaaaaaatcg gaaaattata aatttaggag gaaaataaaa tggagaataa agtgaaaatt
    25381 ggagtactag gatatggagt tgtaggaagt ggacttatag atataataga taataataaa
    25441 gaaaaaagaa atatagaaat agttggaatt ttagttaata atttggaaaa acataaggat
    25501 aaaaaatatt ctaatataat aactaataat atagatgata tatttaataa agatatagat
    25561 atacttgttg aagtcatggg tggtttagaa ccatcattat cttatataaa aaaagcatta
    25621 aacaataaaa ttcatgttgt tacagcaaat aaagatttgt tagctgaatg tggagatgag
    25681 cttgcaaaat tagcaagtga aaataaagta agtattaaat ttgaagcttc agttgcagga
    25741 ggtataccag tattaaaacc aataatagaa tcactagaag gaaataatat agatagtata
    25801 aatgcaattt taaatggaac tactaatttt atattatcta aaatgtatga tgagaatcta
    25861 tcttatgata tggcattaag acaagctcaa gaattaggtt ttgctgaagc aaatccagag
    25921 tcagatgtat tagggtatga tgctgctaga aaactatcaa tattatcaac tctagcttat
    25981 gacaatagag tatattggaa ggatgtgtat ttagaaggaa ttacagatat agatgaaaaa
    26041 gatattgaat atgcaaaaaa attaaattgt aaaataaaat tgattggtca aagtaagtat
    26101 gaaaatgata aagtaagtgc ttttgttaga cctgttttag tagaaaaaga taatatcctt
    26161 gctagaatag acaatgagtt caatgctgtc atagtgaatg gagattcagt aggagaagtt
    26221 tcttttgtag gtaaaggcgc tggaagttta gcaacaggaa gtgcggttta ttcagatgtt
    26281 atagatataa tagataatag agtttcaagt atagattctt ttactaaaga taaaatacaa
    26341 gttaataaaa tagttagaga aaagtgtgga gcacttctta gatttaaaaa atgtaataaa
    26401 gatgaaattc taaatatagt tgagaattgt ttagtaaaat tcgatatttt aaatgatgat
    26461 gatgaacttg ctattatggt ttatgctgat tctgaatatg aaataaacaa cagtttatgt
    26521 ctaataaaag ataaaggata ctgcgaaaaa atgaataaaa tgttgaaaat aagttaaaaa
    26581 agaaaaaata taagtttata tgtaacatat tttgacgatt ttaatactat atagtatgag
    26641 atgaaacaaa acatctcata aaaaaattaa aattcaaggg agagatatgt tatatggaaa
    26701 ataaaaaata tgcaaatggt ggttattcag aagactggta tgaaagagga gaatctacag
    26761 ctaaatggtt ccagaatgat agagaagaat atgaaagagc agcatacgat gaagatagag
    26821 aaagaagagg ctcaaactgt ggatgttcag attcaggaga aaatagacct agaaactgtg
    26881 aaagatttag aagagaagca gagataagag aaagagaagc aagagaagca ttctgtgaat
    26941 cttcagagag aaagaaagaa gcactagcat atgaatgtga agctagaaaa ttatgggaag
    27001 aagcagaaaa atactgggat gaatattcaa aatacaacta taaaggaatc gaatatttag
    27061 cagaagctgc tagattattt gatgaaggta tggaatgtga agctagaaga aatggaaata
    27121 atggaggaaa caataataat tgttgccata aatgccataa atgtaattgt aactgctgta
    27181 gaaaataaaa aaattaattg acaaatcaat agttaaaata tatcatatta tgtataataa
    27241 agagaaaatt cagaaaaaaa taatgattag aagaaatata agtatattta ttagacaaat
    27301 agtgctcagt tagtgaggtg agtacaatat gattaaactc ccatcctcta gcttttgata
    27361 gagggtggga gtttttattt atttatatat cttaaatgag gataatattg taaaataaat
    27421 gagtatgaga ttgtaaaatt aggaggtaaa aaatgaagag tattaaaaca tcaagtatga
    27481 aagaaaaggt agatgaaaag atattaagag agcaagtaag ttctataata gaagatataa
    27541 gaaataataa ggatgttgca cttaaaaaat ataatgagaa gtttgataga aatacaagag
    27601 atgaatttag aattactaag gaagaaataa aggaagctta taagcatgta gatgacgaat
    27661 ttataaataa cttaaagatt gctgccaaaa atataagaga atttgctaaa gctcaaaaac
    27721 taagttttga aaaccctttt gaaaaagaaa tttatccagg tgtaatctta ggtcaaacta
    27781 atattccaat agagtcatgt cttgcatatg ttccaggagg tcagtatcca ttgttttcaa
    27841 cagctcttat gcttataata cctgcaaaag tagcaggagt aaaaagaata gtggcatgtt
    27901 caccaactat gaaaaatact gaaaagataa atcctaagac attggtagct atggatatag
    27961 caggtgctga tgaaatatat gcaactggag gagttcaagc tatagcagca tttacatatg
    28021 gaacagaaaa gattaatcca gttgacataa ttgtaggacc aggaaataag tttgtaactg
    28081 aagctaaaag acaatgttat ggacaagtag ggattgattt tgtcgctggg ccaagtgaag
    28141 ttcttataat agcggatgaa acttcaaatc cagtttatat tgcagctgat ttattagcac
    28201 aatgtgagca tgatttaaat gcaagaggaa tattattgac aaatagcttg gaagtagcac
    28261 aaaaagttga aaaaaatata gaaagtatgc taaaagattt gccaacaaag gacatagcat
    28321 atagttcatg ggaaaataat ggagagataa tattggttga tgatatggaa gaagccatta
    28381 aaataagtaa tttttatgca ccagaacatt tagaagttgc agtaaatgag tataatgata
    28441 tttgtgatag attaactaac tatggttctt tatttattgg aaatctttct gctgaggtgt
    28501 ttggtgacta tgtttcaggt accaatcata cattaccaac acttaaagca tcaagatata
    28561 ctggtggtgt ttgggttgga acttttatca aaacttgtac aaagcagata tttaatgaaa
    28621 aagctataca atcattagca cctgtagctg aaaagctggc aaaagaagag ggattatatg
    28681 cacatgcaaa ggctgctgag gttaggttta aaaagtagta aaaaatttta ttttggcagt
    28741 cgagatttag tgttagactg agataaggaa aacgctgaga acccgaataa atactatatt
    28801 ttgtgggcct cggcgtttct tttatatctg tatataatag gataatacta cctgtgtgtt
    28861 taaatgctag cttaatattt cttttctaaa taatgtttat gaaatagtta atatttttag
    28921 ttaatacttg aaaaaaactt ttgctaactg tgcaaattca tctgcattcg tcaatatagc
    28981 agggtgtcct ccctgactaa aaatgtgaat acttgctttt gaaataaaag ttgccatttg
    29041 tttgtactct tcttcaagat tatgacgaca catttcgtct tccttacttc ctgtaaataa
    29101 aattggcatt tctaatttac acaattcttt atgaaacaaa gggcgtttct cgtttgcaca
    29161 ttgcaataga gcttttgtat caagattaac aacattctcc caatcttttc catgacacca
    29221 ttcatagaat tttcgtgctt gaatatcttg ctttgatttt tcccttccag tgattagatt
    29281 atctatgaag ttatcattaa gagtacgtcc atcaaagcta tctgctataa ttgcttcaac
    29341 taaatcggga cgttctaatc cagtattaac agctgcccat gctcctccac ttgttccaat
    29401 taagccaact ttaccacaat tcaaatgttc aatcaatgct attgtctgta aggcttcatc
    29461 atgccatatg tcaggagaaa attgagaaac tctatccgac tgtccattac ctaaaaaatc
    29521 aattaagata catctaaaat tttctacata taatggcaca agtgctttaa acatattaga
    29581 agaaccagta ttaccatgca ggaaaattat cggtttacct tgtccatatt ctttataaaa
    29641 acaagaatta ccttgatact gaaaatatga catatatttt cctccttttt atttgttaag
    29701 ttaattataa caatataggt atgaatgaaa aacctcatgt tctttcttag aataaaaatg
    29761 tgccacgcat aaaacgtgac acatttctaa ttataaattt tgctgtttaa gtattctttg
    29821 tatgcttttc tctgtcaaaa agtatttctc tgataactgc ttgatactca ttccattttg
    29881 gaaatttata cagatttgag aattacgaga agctaagact tgtttggtgt ttgtgttttc
    29941 accccaatgc tttttgtgct cttgcttttt gggaatataa atcactttac catctatata
    30001 ttcttgcact tgctcaatca gttctttagg cagtaagtca atcgaatttt gatagctcat
    30061 tttgcacctc ctaaataatt attctttagg attagcaaag gctactgcca ctcacaatta
    30121 aaaataaaat tttttattat gtacaatagc ctttgctatg cacaagttcc aattcccata
    30181 aactaaatac tcctttctgg tttgaaaaat tcatctgaac attgatttcg cttttaagat
    30241 agagttcaat gacaaattta catttttatt atatatattc agatagataa ttgcaactgt
    30301 ctttgtatga ggatatttta ttatagtcaa tactataata tgtatttata tcatcaaact
    30361 aatatgaaca gttgaaagga atatgaacaa taaaacttag tcaggaagaa taattatgaa
    30421 gcagacaata gagaaatttg attttaaagt tttattgaaa atttattgac aaatttaact
    30481 tgtaaatatt atactaaact taataaataa agtttataaa gtaaggtgtt gtctatgaaa
    30541 aatatagttg gaaaaccgca aacgataaaa aaagtaaatg aagatttaat aaaaaatatt
    30601 ataaaaaatg aaggtcctat aacaaaacca gaaatttcaa acattactga attgagttta
    30661 gctacagtta ataagattgt agagcaatta gctttgaaaa atgaagttaa agtaagtgga
    30721 ctaagtgaat ctactggagg aagaagagct caattatttg aaataaatgc aaacttagaa
    30781 cacataatag ctttatatta ttatagaaat tgttgtatag gggtagttgc caatttatta
    30841 ggtgaaataa tttatcaaga agaatttaat ataagaatgg atacatatga aaacgttaac
    30901 caagatactt tttttgttat agatactcta ataaaaaagg aaaaaggaaa caatataagg
    30961 gctattggaa ttggtgtccc aggagttgta aaaaaaggtg tagttaaaaa tataccaact
    31021 ataaaaagtt gggaaggtat aaatttagaa aatttaataa agagtaaata caatactaaa
    31081 gtgtttatag aaaatgatac aaatattact actattggga tttatcaaaa acagtataaa
    31141 gacaaatata aaaatatggc tcttatgtat ttagaagatg gtattggttc aggtatagtt
    31201 ataaatggtg aattgtattt aggttctaca aattttgctg gagagttaag ttatctaaat
    31261 atagaatttg gtaagtataa ctctaacaac ttaaatcttg aagattatat tatgagttta
    31321 agaaaaagat atttagaaag taaagataat aaatttaaga aagaaatttt atctataata
    31381 tcaaacttta taaggactct tgtatgtgtc ctaaatccac aagctatgat tatacagtgt
    31441 agtatattaa ccaagagtga catggagttt atagaaaaag atgtaagcaa taatgttgga
    31501 gaagaaaatt ttcctaaatt aataaaagta gagtcattga gagaaggaag tataaatgga
    31561 gtaattagta tgtgtttaaa agaaactgac tatcaatatt ccttatctaa taaaaaagga
    31621 ggatattaat gtgaaatatt tggtttcaat agatggaggg ggaacaaaaa ctaaattttg
    31681 tgtaagtgac ttagatggaa acatacttaa agaacatacc actggttcaa ctaattataa
    31741 gtcagttgga attaaaaaaa catatgaaaa tattaataat ggatttaaaa aaatattaaa
    31801 agatttatat atcgattatg acgatattga gtacactgta tttggtatat ctggttgtga
    31861 ttctcctaat gattataaga ttataatgga tgaaatatta aaaattggga ttaacaaaga
    31921 aaaaatatat ctggcaaatg atgcagtttt agctttttat gcacaagcgg attcccctgg
    31981 tttagtaatt gtggctggga caggttcaat tatactggga attaaagaag atggagaaat
    32041 atatagagtt ggtggatggg ggtataattt tagtgatttg ggttctggat atgatatagg
    32101 gagaaaatta ttaaagaaag tattgcttta ttgtgatgaa tgtcatgagt atagtgattt
    32161 atttagttgt gtcttggatt tctttggagc aaatagtttt gaacaacttg catatatgat
    32221 tactgatata aacaataatg ttgaaatagc aaacttagct tcattagtga ttgattgtgc
    32281 cgaacaaggt gataaattgg ctattgaaat attaagagaa tcatcaactg aactatctaa
    32341 attagctcaa gtaatattga gaaaaatatc taatccaatg aaagtggata aaagcgaaat
    32401 aaatatagtt ttgtctggtg gtacattaaa taaaactgta tatgctcaaa tgttaatgaa
    32461 taatttaaaa acagaaaata cagataaaaa tttaaaattt atatctcaag aaaatcagcc
    32521 agtgtatggg gggataagac ttgctatggc attagctaat aggagggtca agcatggata
    32581 gaaaaaaggt aatagtacaa atttttactg gaggttttaa ggctaaagaa ataaagttta
    32641 atgatataaa atgtaaacta ctagaattat tggactgtat tgatatagaa aaggttatca
    32701 tgggatggag tgtagatgaa gaattatatg tagaaactaa aaaactatta aataaatata
    32761 atgttgaact atatctttgg ttgccatgtt tttctgaaat aggattactt gaaaaaagta
    32821 atttgctaat tgattatatg gggaaggaag tcaagggcta tgctttacaa gaggatgaaa
    32881 attttgagtt ttattgccca aataataagg aaaatataaa aaatataaag aaaatatata
    32941 gtacttattt tagtgatatt aaatttgatg gaattttttt agataaaata aggtatggtt
    33001 ctttttcgaa taaactaaat ggtgttttta attgtttttg taaagattgt ttaaatatat
    33061 atgaaaaaaa taatattgat aaagagtcgt taatgagaga aatgaataat gtgtctaagg
    33121 gagttataga taatgaagat actccatttg gtataacaga atacattaat ggaaaataca
    33181 aatttaaaaa taaaatatgg gaagattttt ttgaaacaaa aaatcaaaat atatacaagg
    33241 cattattaga gataagtaat tattttaaaa gtaagggatt gaaaataggt atagatactt
    33301 tttctccttt tatttcttac tttacaggtc aagatttaga aaaattacaa gaagtagcag
    33361 attttataaa accaatgatg tatagaacta caaaagctcc agctggttta ccatttgaat
    33421 ttgaaaggtt tattgatgaa tccatacata agaataaaga gattggaaaa agaaatttct
    33481 tagatatttt aggaattaag gagtatgaag gagatgtata tcctatagaa tttgtactag
    33541 aggaaatcga ttttatgaca agaaatctta ataaagatat atatgtagga gttgaaataa
    33601 ataaaaagga aattatatct cctgttacac ctaagtacat aagtgaaaat atttcaaata
    33661 taaataagac aacagtaaaa ggatatgttt tatcttggga tttgttgtca gcaccaaaag
    33721 aaaatattga tgaaattata aaatggtttc ggaattagtg aggtgataaa gtgagtaaga
    33781 tattggaaat gcaacaaata tataaaagtt ttggaaaggt agatgtttta aaagggataa
    33841 attttgagtt agaaaaggga gaagtaagag ctcttttggg agctaatgga gcaggaaaat
    33901 ctacacttat taaaatttta ggaggagttc attctcaaac taaaggtaaa gtaattttga
    33961 ctggtaatga aataatgttt aaaaatccac atcattctaa agaaaatggt attagtataa
    34021 tttatcaaga attaagcttg ataccaacgc ttacagtact tgaaaatatt tttcttggta
    34081 gagaaatttt aaaaggaagt gtgtttttaa acaagaaaga catgcttgag gaatgtatga
    34141 aaatttgtga ggattttgat tttaatatag acccacatat ggtagtttct aatttaagtg
    34201 tagcaaacca acaaatggtt gagataatga aagctgtttc atgtaattct gaaattatca
    34261 taatggatga acctacaaca tcacttacta ataatgaaaa agatgggcta tttaaaataa
    34321 taagtagact aaagtctaaa ggtaaaacaa tagtctatat ttctcacata ttagaggaag
    34381 tttttaaagt atgtgatagt gcaagtataa tgaaaaatgg aattatgatt ggaacttatg
    34441 atgtagagga tttaactaaa ttaaagataa ctcaacttat gacaggaaat gataatcaca
    34501 aacttattga gaagaaggat tatacatttg caaaatatga agagccacca gtactagaag
    34561 taaagaatat aagctggtct aacaaaataa aaaatgtttc atttaaagtt tatagaggcg
    34621 aagttgtagg tcttgcaggt cttgtaggtt caagaagaac tgaaattata aatttgatat
    34681 ttggtataga taataaagat agtggagaca tttttatcaa tggtaaaaaa gtagacataa
    34741 cttctcctaa ggttgctata aaaaacaaaa taggattgat tcctgaagat agaaaaaatc
    34801 taggattaat tttagaacaa gctatataca caaactcatc atcagtacaa attgataaat
    34861 tcaagaaatt cttgtttata gatagaaata aagaaattga gttttctaaa aaaggtgtta
    34921 aggaattagg aataaaagtt aatgatgtaa agcaagaagt aaaagagctt agtggtggaa
    34981 atcaacaaaa agtagtagtt tctaagtggt tagagaaaga tttagattta ataatatatg
    35041 atgagccgac aaagggaata gatattgctg caaaagaaga tattttcaat acaatcaaag
    35101 aattttcaag taaaggaata ggagtaatat ttatatcttc tgatttagaa gaagtaataa
    35161 gagtaagtga tagaatttta gtaactagag aaggttctat tgtagatgat ttaaaaaatg
    35221 agaatataca ggttcaagat ataatgaaca gtatatttaa tgtataaaaa atgaaaatgg
    35281 aggactgaaa tgaagaaagc ttttgagaag ttaaatttaa gagattatgg agtattatta
    35341 ggttttttag ctttatgtat agctataagt attgcaactc catcattttt aggtaaacaa
    35401 aatatactta atcttttacg acaatcttct ataattggaa taatttcagc aggtatgact
    35461 tttgttataa tatctggaaa ctttgatata tcagttggag cagtagcagc tcttgcaggt
    35521 gctataacaa tgaaatttgc gactggtgga actaatttgt ttgcatccat gctcttaggt
    35581 gtagcgattt gtgcagtaat aggattaatc aatggtatag tagttgcaaa gataaatgta
    35641 ccatcattaa tagccactat ggctatggtc actattgtaa gaggattgct gttgatgctt
    35701 acaggaggat atccaattac tgaaaatata ccaatacttg attacattgg aaatggatat
    35761 ttgtttaata taccaatacc agtagtaatt ttctttatag tggtgttagc ttcatttatt
    35821 gtacttaata aaactaagtt tggtagatat gtttattctg taggagggaa tcaagaagca
    35881 agtaaactta atggtataaa tgtagattct cacaaagtga aagtatttat tattaatgct
    35941 gtacttgcag gaatagctgg aatcgtacta acaggaagac ttgggactgc aactgcgatt
    36001 gcaggtgaag gatatgatat ggatgcaatt gcatctgtag taataggagg tacatcagtg
    36061 gcaggaggtt ctggttctgt acttaaaact gttataggag tattacttat gagtgttata
    36121 aacaacagtt ttaatcttct tggaatagat gtatatttcc agtacatatt taaaggatta
    36181 ataattttag cagcagttgg atttgattct tatagcaaga aaaaacttgc ttcaagataa
    36241 aaaataaggg ggattttttt atgaaaaaat taatgaaaca tttagcattg ttgctatcac
    36301 ttgttatgat atttggttta gttggttgtt caaatggtgg tgacaaagaa aaaaatggag
    36361 aaaagaaaat agcagtatta ctaccaggtt caacaggtta ctttgtagca actaaacaag
    36421 gtatagatgc aaaatctaaa gaattaggtg taagcgtgga atatgcagat gctcaatggg
    36481 atgctagtaa acaattatca caagctgaag attttatggc taaaggggta gacatgattg
    36541 cattatgtgg agttgattct gctgtaagtg agagaatagt taaagctgct aatgattcag
    36601 acgttcctat agtagcattt acaaattcta taggaagtaa cccaactgga gaatttaaag
    36661 gtttagttac atatatagga caaaatgagg aagaaacagg agcattaact ggaaaaattg
    36721 ctaaaaactt attaggagaa actggtggga aagctgtatt aatagaagga gtaccaggaa
    36781 ctactccaca agtattaaga aaaaaaggtc ttgaaaaaga attaaaagat agtaatatag
    36841 aaatagttta taatcaaact tcaaattggg agaaagagca agctttaaag gtaacagaag
    36901 atttaattca aaagaaaact gattttaatg ttataatatg tcaagatgat aattctgcta
    36961 caggtgcagg tcaagcttta aaagatgctg gtcttaagga taaagttaaa gtcataggtt
    37021 tgggtggaag taaagatgga ttaaaagcta taactgatgg gttaatagat ggtacaactt
    37081 atatgtctgc tgtagaagaa ggtggattag tcatagaaaa ggcatctaaa ttccttaaag
    37141 gtgaaaaaat agaacctgtt acacaaatta aacaagttga agttaacaaa gataatattt
    37201 cagagttcaa gggtgaatgg taaattgtca tagataataa ataagatttt tagagttact
    37261 ttagaaacta tataaagtaa ctcttttttt aatttaattt agtgataaat tattgaatag
    37321 tatttctaaa caaataaaaa attaatataa acaaagactt aattatacta aattataagt
    37381 aaaactaata taaacttatg gaaaaaagga aaacgtctaa agtattggaa ttactatagt
    37441 gtaggtgtgg tattaaaaaa acataaaaaa acataaaaaa attgttgaaa aaaatataga
    37501 aattttgtat aattaaagat ttgaaaagtg cggtatacaa agccaattct tttgtatata
    37561 atatatataa attcagaaaa aggaagggat atgtatggcc aggcggttat ttttagaaag
    37621 gattggactt atatttttag gttcagcaat attagcattt ggagtttata atttttatta
    37681 tttaaacaac ataacagaag gtggagtgtt aggtatttta ctactgttaa aaaatttatt
    37741 caatatacaa ccagcaatag caaatgttgt aatagatggt ttgctacttt tagtaggata
    37801 taaatttttc ggtaaaaaat tccttatata ttcaatagta gcttctataa ctttttcagt
    37861 gttatatgac ttatttgaag ctataggacc tctagtacca caatcacaaa atatgctttt
    37921 atcaactatt ttggcaggtg taactgttgg aactggtgta ggtatagtag taaaagcagg
    37981 ttgtgcatca ggaggagacg atgctttagc attagtaatt tctaagacta catctttgaa
    38041 catagggcaa gtttatttag caacagatgt tattgtattg ttgttatcat tattttatct
    38101 atcagcgttt gatatctttt attctttgat tgctgttaca attagtggca aggtaattga
    38161 ttttatttat tatcatggta aaagtttgga tatggatata agtaatgata tagttccaga
    38221 atgttaatat aaattaaata actttagatt ttattagggg tggcagattt gccacctttt
    38281 ttgtgtctaa atctttatag aaagtataat cctatctagg tttttgcaaa tctcaaatat
    38341 agaattatgt tgaaatgact gggaatacga ttgctagatg tgcattttaa aaacccaatt
    38401 ttatatttat gaaatactaa tcattaatgg atgtttctta atcctatctt tatacctaaa
    38461 atgataagat aaatgaagta gcaatacaaa actaaaattt gtaaaagaga ttaaattaaa
    38521 tggaggagct aaaatgttgg atatagttat gatagcattg ttattcatag gatttgtttc
    38581 catgaagtta cttgctgatt ggtgtgggaa acaaactgaa aaaaaataat gtaatgtatg
    38641 gagggattac ctatgtggtt tctggcagtt gtaattataa tgttaataat atatttggta
    38701 tatgcgctta ttaatcctga aaaattttaa acagtataag gctaataagt aagttgaatt
    38761 ggggggaaca atttttatgg tgcagatagt aatagtgtta gcgattttta tgattttagt
    38821 aatacctatg ggcaagtatt tatatcatat agctactaat caaaaaacat ttggagatag
    38881 actatttgat aaagtggaca attttatata taaggtatgt agtatagata agaaaaaaga
    38941 aatgaactgg aaacagtatg cattagcttt attatttaca aatgcagtta tggtatttat
    39001 aggatatatc atacttagaa ctcaaagtat gcatattttt aatccaagtg gaattaaaag
    39061 tatggaacaa ggactatcat ttaatacaat aataagtttt atgacaaata caaatcttca
    39121 acattattca ggtgaatcag gactttcata ctttagtcag atgacagtga taatatatat
    39181 gatgtttaca tcagctgcaa caggatatgc ggctgctatg gcatttgtaa gaggtctagt
    39241 cggtaaaaag aaaacattgg gaaattttta tgtagattta attaggataa caacaagagt
    39301 acttttacca ggagctttaa ttattgggct tatattagtt acacaaggag taccacaaac
    39361 ttttgctggg acagaaacag tgactactat agaaggaaag cttcaagata tagctagagg
    39421 tcctgtggca gctcttgaat caataaaaca tttaggaaca aatggtggtg gattctttgg
    39481 ttcaaattca tcacacccat ttgaaaatcc aacaataata tcaaatatag tagaaatatt
    39541 atctatgatg atattaccag gagcttgtgt tgttgcattt ggtcacatga taaagaataa
    39601 aaaacaaggt tgggttgtgt ttggcgcaat gtcaatcata tttttaatag gtctagtagt
    39661 gtgctttaaa gcagaaagtg caggaaatcc tattttatca caattagggc ttaatcaaag
    39721 tatgggaagt atggaaggta aggaagttag atttggtata gcacaatcat cattattcac
    39781 aacagtgact acttccttta cgacaggtac agttaataat atgcatgata cactgactcc
    39841 tttaggagga ttagtaccac ttttaaatat gatgctaaat gtagtatttg gtggtaaagg
    39901 cgtaggtctg atgaatatgt tgatgtacgc tataatagca gtattcttat gtggattaat
    39961 ggtaggaaga acaccagagt ttttaactaa gaaaatcgaa ggaaaagaaa tgaagcttat
    40021 tgctttactt attatattac atccactttt aatactaatg ttctctggtc tttcagtagc
    40081 aataccagca ggacttgaag gaatttcaaa tcctggattc catggattat cacaggtatt
    40141 gtatgagttt gcatcttcag cagccaataa tggttcagga tttgaaggtc taggagataa
    40201 cactatgttt tggaatataa caacaggtat agttatgttc tttggaagat atgtgtctat
    40261 tatagtacta ctagcaatat caagtttgtt agcatctaaa aaagctgtaa atgaaagtat
    40321 aggaacactt agaacggata attttacatt tacaatagtt ttagtacttg ttgttttaat
    40381 tgttggtgct ttaacatttt tcccagcctt agcgcttgga cctatttcgg agcatctagt
    40441 gttgtggcac taaaaaattg ggagggagta aagttttatg gaaactaaaa aaacaaagtt
    40501 tattacaaaa gatattttca aaacttccat tatagaagct tttaaaaaat taaatcctaa
    40561 atatatgatg aaaaatccag ttatgtttgt tgtagaaatt ggatttatag taacattgat
    40621 acttacaata gtacctagtt tgtttggtga tgaaggcaat aacttaagag cttataatgg
    40681 gattgtaaca ataatcttat ttataacagt cctttttgca aattttgctg aagctgtagc
    40741 tgaaggaaga ggtaaagctc aagcagatac acttaagaaa actagaaaag atacagtagc
    40801 aagggttata gatacgttag gaaatgaaaa aatgataagt gcaagtgagc taaaacttgg
    40861 tgatattgtt ttagtaaatg ctggagaagt tatcccaaat gatggagaag ttatagaggg
    40921 tatagcttct gtggatgagt cagcaataac tggagaatct gcacctgtca tgagagaatc
    40981 aggtggagat ttcgcatctg ttacaggtgg tactacagtt gtaagtgact ggttaaagat
    41041 aagaataaca acaaaaccag gagaatcgtt cttagataaa atgatagctc ttgtagaagg
    41101 tgcttcaaga caaaaaacgc caaatgagat tgctttaaat actttgttag tagggttaac
    41161 acttatattt atggttgttt taatatctct ttatccaatg gcaaactatg caggtgtaaa
    41221 gattccaatt tctactatga tagctctctt ggtatgttta ataccaacta ctataggtgg
    41281 attgttgtca gctattggta ttgcaggtat ggatagagta actagattta atgtaattgc
    41341 aatgtcagga aaagcagtag aagcttgtgg agacgttgat actatgattt tggataagac
    41401 aggtacgatt acttatggga atagacttgc atcagaattt atagcagttg gaaatgcaga
    41461 ttcaaaagat ttaataaatt attctgttat gtgttcatta aaagatgata caccagaagg
    41521 aaaatctata gttgatttag gtatgaaatt aggttcaaca ggtaagacaa aagaggcaga
    41581 ggaagctgag tttgtagaat tttctgcaca aactagaatg agtggtatta acttagctga
    41641 tggtagagct ataagaaaag gtgcttatga tagcataata aaaagagtaa aagaatctgg
    41701 tggtacagtg ccagaagatt tagaagaaaa tgtaaatcga gtagctaaac taggagggac
    41761 acctttagta gtgtgtgtag ataatgagat atatggaatt atctacttaa aagatacagt
    41821 aaaatcaggg cttgtagaaa gatttgctag acttcgagag ataggaataa agacaataat
    41881 gtgtacaggg gataatccct tgacagcagc tacaattgca agagaagctg gagtagatgg
    41941 atttattgca gaatgtaaac cagaagataa aatagatgca ataaaaaaag aacaattaga
    42001 gggtaaaata gttgcaatga caggtgatgg aacaaatgat gctcctgcac ttgctcaggc
    42061 agatgtaggt cttgcaatga atagtggtac aacatctgca aaagaagcag caaatatggt
    42121 ggatttagat tcagacccaa ctaagatatt ggaagttgtt gaaataggaa aacagctttt
    42181 aataactcgt ggggctttga caacatttag tatagcaaat gatgttgcaa aatattttgc
    42241 gattatacca gctatattta ctcttgcaat acctcaaatg gagatattaa atgtaatgaa
    42301 actttctacg tcatttagtg cgatattatc agctttaata tttaatgcta taattatccc
    42361 atgtttaata cctcttgcaa tgaagggagt aaaatataga cctatgaaat cacaagctat
    42421 gttaatgaga aatatgctta tatttggtct tggtggagtt atagtaccat ttttaggaat
    42481 aaaattaatt gatttattga ttacaccttt agtaatggtt cttaatttag gttaataaat
    42541 ggaggatata aaaatgaaaa cattaaagcc agcattactt gtaagtattg tattgttagt
    42601 tgtttgtgga cttgtatatc cacttgtttt gacaggtgta agccaagttg catttaaaga
    42661 taaagctaat ggaagtatga tagaagtaaa tggtgtaaaa gtaggttcag aacttattgg
    42721 tcaaagcttt acagatgcga gattctttaa gggaagagta tcatcagtaa actataatac
    42781 ttatacaaaa gaagatttag taccagataa agatggaaac acatcttatg gaggtgtatc
    42841 atcagggtct tttaattatg gagctacaaa tccagaactt catgatagag tacaaaaaga
    42901 tatagaacag tttttaaagg ataatccaac tgtcaaaaga gaggatatac caacagattt
    42961 acttacagca tcaggttcag gacttgaccc taatataagt ccagcctctg caaaaattca
    43021 gataccagct atagcaaaag cgtctggaat atcagaaagt aaattacaaa aaattgtaga
    43081 agataatact tccaaaaaac tttttggagt tttaggtgaa gatagagtta atgtattaaa
    43141 ggttaatgta gaggtcgcaa aaatattagg tcttatatag tattttgtgg aattttagca
    43201 acaaaatatt actcaagatt taatttaaag gttaaatttt aaagagtgaa aatcgataat
    43261 gattttcact tttttatttg aatattacta atatttggaa taaagtgatt gtaagtataa
    43321 aatccaaaaa aaggttgcat tatcaaaatg ataatactat aatatattta tcgttatcaa
    43381 tttgataata gatttggaca tataggagga aatagtatgt tatataataa cgcattagag
    43441 ttgataggaa acacacctgt agtaaggctg aataatttag gctgtactaa tgggtgttct
    43501 aacatatatg taaaattaga aaaagtaaat ccagcaggaa gtataaaaga tagagctgtt
    43561 tatgaaatgt tagagggttt agagcaaaga ggagaattaa aaaagggaga tgtactagtt
    43621 gaagcaacta gtggaaatac tggtattgca ttatctatga taggaaaatt aaaaggatat
    43681 gaagtagtaa tcgtaatgcc cgaaacaatg agcgttgaga gaagagattt aatgaaggct
    43741 tatggagcaa atttggtgct tacagatggt aaagctggaa tggcaggttc catagaaaaa
    43801 gcaaatgaac ttttaaaaga aaatccaaac tataaaagct taaaacaatt tgaaaataaa
    43861 gataatccaa atgcacatta taaaacaaca gcagttgaaa ttatgaatga tgtcaaagat
    43921 ttagatatat tcgtatgtgg agttggaaca ggtggtactt taataggaac tgcaagatat
    43981 ttaaaagaac aaaatccaaa tataagagta attgcacttg aaccaaaaaa atctccagct
    44041 atatcagaaa acaagactgg acctcataaa atacaaggaa taggtgctaa ctttgttcct
    44101 gaaaattatg attctagtgt agttgatgaa gtaatattag tagatgatga agatgcattt
    44161 gatacagtta aattacttgc agcaaaagag ggaattttag tagggatatc ttctggagca
    44221 aatatatttg gtgctataga gatggcaaaa aagtatccag ataaaaagat agttacagta
    44281 gctccagatg gagttgataa gtatatgtct atgggaatat tttaataatt ttatttgagg
    44341 gagtgaatac tttgtttaag aaaataaata aagatattga atatataatg aagaatgatc
    44401 cagcagctag gtctaagata gaagtttttt tactttatcc atcagttcat gcaatgataa
    44461 tgcataggat ggctcatgct ctttataaga agaagaagct ttttacagca agattaatat
    44521 cccagatatc cagatttatg actggcatag aaatacatcc tggtgctaaa atgggggaag
    44581 gtatattgat agaccatgga atgggtgttg taattggaga gacagctgaa gtaggtaata
    44641 gggtgacaat atatcaagga gctactttag gagctacagg aaaagatact ggaaagagac
    44701 atccaactgt tggtgatgat gtattaattg gtgctggaac aaaaatacta ggacctttaa
    44761 atataggttc aaattcaaaa attggtgcaa attctgttgt cgttaaggat gtacctaatg
    44821 gtgcaacagt tgttggtata ccagcaaaaa tagtaaaaat aagaaaccta gaacctgtaa
    44881 aaaagaataa aaaagaagtg tcctatgagt atgatgaatt agataatgta tattatatat
    44941 aggatttata taactataaa ataaacttta taaaaattat tttaaaaggt atttttttca
    45001 aatttgagga cataataaaa aagaactgaa tgttacagtt ttggttcatc aatctttgat
    45061 aaacaagatt ttaaatttgt agcgtctagg aggattttat tatgaaagca aatgttaatc
    45121 aagatacttg tataggttgt ggattatgtc catcaatatg tccagaagta tttgatatga
    45181 aggatgatgg gaaatcacat gttatagttg atgaagtacc aagtgatgct gaagaatcag
    45241 cagcagaagc tagagaaagc tgtccagttg atgcaataga tgtgcattaa taaaataaat
    45301 gcctataaaa attgaatttt caatttttat aggcatttgt cttttattca gttagtattt
    45361 caacacctgt ttctgtaact aaaaccatac attcccattg agcagataat ttaccatctt
    45421 ttgtataaat agtccaatta ttttcttcat caacaaaaat ttcgtgagtt ccttcattta
    45481 ccataggttc tattgtgaat atcatcccag gaaccaatag catctcagtc ccttttttag
    45541 atacataact tacaaaaggg tcttcatgaa agcttaatcc aactccatga ccacctattt
    45601 ctctaacaac agagtatcca tttttctttg cataagagtt gataacatca cctatatctc
    45661 ctaagaatcc ccatggtttg gcaacttcaa gacctttttg gacacattcc tttgtaactt
    45721 gaactaattt ttttgcattt tcgttaacat tacctatcat aaacattctt gaagcatctg
    45781 aatagtatcc gttaaaaata gtagaaacat ctacatttat aatatctcca tcttttaaga
    45841 taatgtcttt acttggaata ccatgacaaa cttcattatt tactgatgta catacacttt
    45901 taggaaatcc attatagtct agtggagcag ggatagctcc attttgtagt gtaaagtcat
    45961 gaaccaactt atttatatct tctgtagaca ttccaatttc gattttatct gaaatataat
    46021 ccaaaatttt tgtgtttatt acagcacttt tttttatttc ctcaatttga ctttcatttt
    46081 ttataatatc atgagttggt acaatatgac ctaacttagc aaatgaatct attttattat
    46141 ccatatccat atgacatttt ttatattttt tagtacttcc acaccaacag ctatcatttc
    46201 tatttaactt cataactttt catccttctt ttattattta tttaaattat gggttacata
    46261 aactatttta aaacataacc attataaata ttataacata aatactaaga aatcctttat
    46321 agatagtgat ttattcaaag tataaattat t
//
LOCUS       DAEPHU010000025        44807 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 01A10CD0081
            SAMN05941466-rid12468953.denovo.025, whole genome shotgun sequence.
ACCESSION   DAEPHU010000025 DAEPHU010000000
VERSION     DAEPHU010000025.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941466
            Sequence Read Archive: SRR6291087
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 44807)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 44807)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068158.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 22:43:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,892
            CDSs (total)                      :: 3,805
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 87
            rRNAs                             :: 8, 1, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 55
            CDSs (without protein)            :: 55
            Pseudo Genes (ambiguous residues) :: 0 of 55
            Pseudo Genes (frameshifted)       :: 21 of 55
            Pseudo Genes (incomplete)         :: 28 of 55
            Pseudo Genes (internal stop)      :: 16 of 55
            Pseudo Genes (multiple problems)  :: 8 of 55
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..44807
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941466-rid12468953.denovo.025"
                     /strain="01A10CD0081"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            <1..1089
                     /locus_tag="KR231_001504"
     CDS             <1..1089
                     /locus_tag="KR231_001504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exonuclease"
                     /protein_id="HBH0003886.1"
                     /translation="YARIVEIDKNYNDFEFRVVPLKIADLFEENILSQLEKGIFLSAT
                     LSLSESMSYFKNTLGIDRVKNVEKIIEPIFDYKNRVSVVGFSDICEYRNSEFPNEMSK
                     IISNISKITEGHTLALFNSKDRQEKTYEILKKYLHSFNLEIYADKKGIRHLNDLNRKC
                     VVLGSKGCFEGVDIPGDGLVCVTLDKLPNLNPKDPLYFTIMKKYGIDYYTINYPQMTI
                     KVKQAMGRILRSKYDYGCFVIFDVGTNISVLKRLEKDLHDCKISKVNSNEFYTYIRRH
                     LNKYRSLILKSVIFDTIKALNVDAKMDNNDVDKDIIKKDINENIRQRAVKGEVYHIDI
                     IKKDMKVKYFDRNYLINLDIFMREEDKN"
     gene            1107..1706
                     /locus_tag="KR231_001505"
     CDS             1107..1706
                     /locus_tag="KR231_001505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease H family protein"
                     /protein_id="HBH0003887.1"
                     /translation="MAKQKFYAVKKGKNIGVYNTWDECKKQVNGFSGAEYKSFSTFQE
                     AKEYIDGSEKLSFQEDKEFIEAYVDGSYEHSVKMYGSGVVILKNNEVIKTYSEKGKEK
                     TLVSMRNVAGEIEASKIAMQYCIDNNVQNLILYFDYEGIEKWCTGVWKTNKEGTIAYK
                     NFYDSIKNKLNVKFTKVKAHSGNKYNEEADKLAKKAIGV"
     gene            complement(1963..4092)
                     /locus_tag="KR231_001506"
     CDS             complement(1963..4092)
                     /locus_tag="KR231_001506"
                     /EC_number="1.11.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peroxiredoxin"
                     /protein_id="HBH0003888.1"
                     /translation="MPNLPSLGSKAPDFKANTTNGPIRLSDYKGNWIVLFSHPGDFTP
                     VCTTEFLCFAKYYDEFKKRNTELIGLSVDSNSSHLAWMYNISLLTGVEIPFPIIEDRD
                     MRIAKLYGMISKPMSDTSTVRSVFIIDNNQILRTILYYPLTTGRNIPEILRIVDALQT
                     SDRDNIVTPANWFPGMPVILPYPKNYKELKNRVNSCNKKYSCMDWYLCFVPDNYNDEE
                     VSKKIDNTCSWKKEHTKNIENECNCEHEHHDYLNKALDCKQEHKTDIKDDCNHEKKHT
                     KNTNKVHNSKQDKFKDKSCDEMNFNYDKDESCDKINSSYNKEDSSYEDFYKHNYKNYD
                     YTSEKNTKKIAMKTLKDSKKLVRPQITDPYNPIVENANCPDINPIVAEYVLGNPTNVD
                     AQLLDAVIFAFAEIDQSGNLFIPYPRFLNQLLALKGEKPSLKVIVAIGGWGAEGFSDA
                     ALTPTSRYNFARQVNQMINEYALDGIDIDWEYPGSSASGITSRPQDRENFTLLLTAIR
                     DVIGDDKWLSVAGTGDRGYINSSAEIDKIAPIIDYFNLMSYDFTAGETGPNGRKHQAN
                     LFDSDLSLPGYSVDAMVRNLENAGMPSEKILLGIPFYGRLGATITRTYDELRRDYINK
                     NGYEYRFDNTAQVPYLVKDGDFAMSYDDALSIFLKTQYVLRNCLGGVFSWTSTYDQAN
                     ILARTMSIGINDPEVLKEELEGIYGQF"
     gene            4358..4606
                     /locus_tag="KR231_001507"
     CDS             4358..4606
                     /locus_tag="KR231_001507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0003889.1"
                     /translation="MMICFAMTFALVLINSVMGVHIGLDYYFLMGSVLTVCLTIGIVL
                     CNARKIFDSKAIHKTRTKTVSNNKKQKSHSRDIKRKIS"
     gene            4772..6163
                     /locus_tag="KR231_001508"
     CDS             4772..6163
                     /locus_tag="KR231_001508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UbiD family decarboxylase"
                     /protein_id="HBH0003890.1"
                     /translation="MNFRDLFEKAVDFIDEKRKSIVAISLSTLGVIALIIVFFLSSNE
                     FSVGNEANELLKIIEKRQYSIAVDYYTSIEKKFSDSKMERFNKSVSKKINKLLLNSGD
                     KYLDGDISQESFIGLINTVKELNKISIDVDDLLAQADRVREMYKEENTTYDIAINYIS
                     TVSILNGMGSNLDVYKQNIETIKESRDVYDSAVKDQKAYKYYEAIEKYNKVLKEDEKY
                     YSMAQNGKEQCIEEMYDYYISRAEEANTSGDYERALQYIEYLKDDYSDDEKVQSLEKK
                     YKKNLSLYTLTSDDIINVIAKKSGKDKANLSINSLPQMIKNNKYYYAEVYEYDKLINE
                     VLVSAKTKDLYSYKDGKKDYKVDYGDGYFRILEDGSYQFGITKDKAKFVLTNTLDEKE
                     NKYKKIEILDIEKADRYVKSKKSLEELFGKYKNIYYYAVVNKGLFRGKEVYAINIYNE
                     KIYAISENGLNEY"
     gene            6278..7747
                     /locus_tag="KR231_001509"
     CDS             6278..7747
                     /locus_tag="KR231_001509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanW family protein"
                     /protein_id="HBH0003891.1"
                     /translation="MSNVNKKLVIAIGAVALVVIIFIGIMCMQFKGEKIAKNTYVNGV
                     NIGKLTKSQAKQELAKKYKLENVDFNYNDKSWKVKSKDLNLSTDLDKTVENAYNLNRK
                     SAFFGNLSKTISANFGKKSNLVVAINYDKNKLKAEMEKIAKEIDVDVKDATLDISGEK
                     VKVIPDSDGLKMDISKSMENFDNQTKKGNYKNELVVKATPAKVKKEQLANIDTNLGTY
                     STTFKTSQINRSINIKLATDNISNVLLMPGETFSFNKHTGKRSKENGYKSAPVIMEGE
                     MEEDYGGGVCQVSSTLYNSVLYAGLEIVNVKNHTIPSSYVPKGRDATVADSGIDFLFK
                     NNLKHPVYIKNYVSGNQIVCNIYGSAEDKQNITISTKLDGVSQTTMKRVNDPTMPKGK
                     EKVDKSGRNAYSVSTYRTFNDANGKKIKTEKIANSYYPKKEGIILVGTMEPKPEEKPN
                     TDENKNNQNTNNQNPNNQQKPETPPTDNKPNETQPQPQA"
     gene            7812..8405
                     /locus_tag="KR231_001510"
     CDS             7812..8405
                     /locus_tag="KR231_001510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fis family transcriptional regulator"
                     /protein_id="HBH0003892.1"
                     /translation="MNLNNITNYVQSICENISNVLDVDVTLVTKDLTRIAGTGIFRGK
                     IGETISEKSVYSLVLKDGKSYVINKEIEENCNKCANRENCKELADICTPVKMGEHILG
                     ILGIAAFNEEQKEKILSKDKELTAFVRSMSDLISFKLDELYKQEVKTIDDLEREAIEN
                     AIKKYGSNTEGMKKVAEALNIGIATLYRKVKKFNIKS"
     gene            8587..9933
                     /locus_tag="KR231_001511"
     CDS             8587..9933
                     /locus_tag="KR231_001511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HBH0003893.1"
                     /translation="MPRKILDISLIEDNKSDLTFFNIEEEDGDETLKALKQSYVTTNY
                     KEETLLNLQGALNSKSDTTSKELKLESYKRYNNALDLAYKNYITSAINMVNKALEINP
                     KDIDILNLRGLLKLLKCDFAKSFESFYTALCYENNHISRKYVNLISSEDFKTFLGRYN
                     HSIRFINEELNYESIHILENIIEEEPELIEPYVILSLLYDKLGNVKKREGYLDKLKEL
                     DKDNPVFEKNEEEKEDTSKKEEIKKVKRKKSILPYIIVGCVLIGMGIYLIQSKKRIEN
                     LNNQISSKEEKLSETDKKLGETSKKLEKTNKELNEVKNKEPEREITVADEEDLYYQAL
                     NLKKNKEYEKAIDNFKSVVSSGKTKKYISESIYQLAITNKLLGNKDEAIKYYKKYINT
                     YTKNDQYYDDSYYELGMFYYDNGDLKNAQQTFYSLRSEVPDSMYNNSKIKEILSEK"
     gene            10115..10486
                     /locus_tag="KR231_001512"
     CDS             10115..10486
                     /locus_tag="KR231_001512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CidA/LrgA family protein"
                     /protein_id="HBH0003894.1"
                     /translation="MKVFNQLVIILSIWVIGEYISSFIQGIILIPGSIVGMLLLFLLL
                     QFKVLDLSSIENVSGFFLDNMAIFFIPAGVSLIKSLDLIRENVLVLLLVICLSTLIVM
                     YTTGIIVEKMIKKKEEGQKNV"
     gene            10479..11168
                     /locus_tag="KR231_001513"
     CDS             10479..11168
                     /locus_tag="KR231_001513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LrgB family protein"
                     /protein_id="HBH0003895.1"
                     /translation="MYNVLQTPVFGIIVTIVFFNLGRYIQRKTSNPICNPLLIAIVGI
                     ILFLSISKIPYENYKIGADSLNFFLGPVTVVLAVPLYKQFELFKKHMFEIIVGIGCGI
                     VISFVSVLIIGKIANSDVSIINSLIPKSITTPMGISLANSLNGVESITVVAIIFTGIF
                     GGMVASTVFKLGNINHPVAKGIALGTSAHALGTTKAFELGEIEGAMSGVSIGVSGTIT
                     VILIPIIMNFI"
     gene            11688..12554
                     /locus_tag="KR231_001514"
     CDS             11688..12554
                     /locus_tag="KR231_001514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HBH0003896.1"
                     /translation="MSEVKNTLQKHPVLRYSTMLFGMLMTSIGINGFLRPAHLLSGGA
                     TGIATSINYLTNINVGLLTFLINIPIFILGFIYLEKEFCISSLVNMIVFSLLLGATQE
                     ISNIIPIHDILLQSVYGGILSGLGVGVVFRTRSSQGGTDIIAAILKIKKNIEMKDTAL
                     AINGLIVLTGSFLFGLDLALYTLIGLFLNAYSMSFIKDAMNYQKSVMVMSNEVDLIAE
                     DIMKSLVRGVTFLDAEGAYTHQKKKIIYTIVSSNEIPKIKDIALKYDKKAFISVNDVT
                     EVKGRGFKAKDL"
     gene            12796..13605
                     /locus_tag="KR231_001515"
     CDS             12796..13605
                     /locus_tag="KR231_001515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0003897.1"
                     /translation="MNLSKEYVNLYDNYLKYINEVNKEIRSIKNMKKRVLKRGDFAPE
                     NEVLELEGKTIRDIDDVDTKKPKNKIYKFSNGDVYVGKFLEGKMEGKGSYTFFVDEGT
                     VMEYIGEFKEDKKNGKGNFIFSNGNEYIGYFEEDMMSGIGNMLYSSKDEYIGTWKNGK
                     KDGKGIYKWSDGCIYAGEFKGGKMEGYGICYNSKGEVLYEGEWKNNLIHGKGTYIWEK
                     GKKYIGEFMHGKKHGQGTFYLNNELVYEGTWKFDKPSIFDRTLDEIFSLRL"
     gene            13749..14813
                     /locus_tag="KR231_001516"
     CDS             13749..14813
                     /locus_tag="KR231_001516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728685.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase"
                     /protein_id="HBH0003898.1"
                     /translation="MKRLIALVLVVLIVLFYSPELLKEGYDLKEKFFQSEIWNEFLDK
                     ININDNSKKDKKEKSQNLQSNNTEGENLGESDIKNFEKISLGDNLSYVLSSIGKPGRI
                     DISEYGFDWYVYNQYGKEFAMVGLENDEVVALYSNSINSCENQDIKLNQDRQTVRTKI
                     TPLKYKRKGNTRYIINSENQYDIISKEGKYITIFYDIHEENRVCSYLIIDKSTEDEFK
                     NLYPDDSEELKKCFELEVIDLVNSVRNQRGLNSLRYSEQATLSSRKHSEDMRDNNFFD
                     HVNKKNETPFDRMKREGIVYTSAGENIAAGQINAIYAHEAWMNSEGHRKNILGNYNNI
                     GVGVIFGGSYKTYYTQNFYK"
     gene            14841..15560
                     /locus_tag="KR231_001517"
     CDS             14841..15560
                     /locus_tag="KR231_001517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HBH0003899.1"
                     /translation="MTSWKKKTVYKCLIAVALFCGIVLISNFSKVSALMMDTNGNVLI
                     KHGSREKKLIAITFDDGPHPKETSQVLDVLKKYNVKATFFIAGKHAKWYKEPLVRASK
                     EGHEIGNHTFNHPDISNLSSSQIEEEIVKCEDILKEVTGKKPTLFRPPFGSYREKDLI
                     EIAKKHDYKVVLWTGVDVKDWKNPGANSIADKIINKVQNGDIILLHDYATNDTVEALD
                     MFIPKMIEKGFKFVTVSELIK"
     gene            15584..16168
                     /locus_tag="KR231_001518"
     CDS             15584..16168
                     /locus_tag="KR231_001518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminodeoxychorismate/anthranilate synthase
                     component II"
                     /protein_id="HBH0003900.1"
                     /translation="MILMIDNYDSFVYNLVQYIEELGEAVVVKRNNEIKISDIEELNP
                     EVIVLSPGPCSPKEAGICIDIVEHFKGKKPILGICLGHQTIGHVFGGDIIKAQQPVHG
                     KVYSINHTNKGVFRGLKNPLNVTRYHSLIVDSNTVPKELEITAITDKGEIMGIRHKKY
                     LIEGVQFHPEAILSEYGHEMLKNFITEARERVHM"
     gene            16170..17519
                     /gene="pabB"
                     /locus_tag="KR231_001519"
     CDS             16170..17519
                     /gene="pabB"
                     /locus_tag="KR231_001519"
                     /EC_number="2.6.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminodeoxychorismate synthase component I"
                     /protein_id="HBH0003901.1"
                     /translation="MIREINTKLNSFEIFTIFRNEHDSFILDSAMDKEKLGRYSFISS
                     QPFKVLKYKDTDENPLEVLKEELHKYRVVNDTNLPFVGGAVGYLSYDLGNYIENLPRT
                     AVDDIEMPDMYFGFYNHVIVIDHLVQKTYIATPNIDIELEEKIIDDIEQRILKEEKKG
                     IDSICYEEKEVTPIRLKSNFTKEEFKNAVQSVREYIRQGDIYQANLTQRFSGETELTS
                     FELYRDLRRFSPAPFGAFLNFEDAHILSNSPERFIRCVNKRIETRPIKGTRPRGKDKE
                     EDLRLQQELRNSEKDRAELLMIVDLERNDIGRISKTGSVKVPELFVIEPYANVNHLVS
                     TVVGELKDDKDATDVIKATFPGGSITGAPKIRAMEIIDELEPTQRNVYTGSIGYIGFN
                     GDMDFNIAIRTIIKNDKKVYFQVGGGMTWDSDPDEEYQETLDKAKSIMKALRGYYEE"
     gene            17509..18252
                     /locus_tag="KR231_001520"
     CDS             17509..18252
                     /locus_tag="KR231_001520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class IV"
                     /protein_id="HBH0003902.1"
                     /translation="MKNNVGFDSSLSKFGIGLFETIRVKNGIAVDLDIHIERMLSSIN
                     CLDLDINYKKDFLINEIVTYIKKENVINKALRITVFDEGYNISIRDIPYNQETYEKGF
                     KLAISPIVRGNSLIHRHKTTNYFENIYTKNIANKTGYNDGIFLNSEGVILECSMSNIF
                     FIKGERVYTPSDRLPILNGIIKKRIIEICDELHIELIENEINISEISSFDFVFVTNSL
                     MGAIKVTEIDKIKFNKENVVFDKIVKLLE"
     gene            18286..18987
                     /locus_tag="KR231_001521"
     CDS             18286..18987
                     /locus_tag="KR231_001521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0003903.1"
                     /translation="MIGCIYEVYNEEMTKIIENQNTLAVYLVGSSKDVDFTLYDVVIN
                     DIDVFVFVKEGEKQERILFKKKGIEFDVNYFSKDGVKKLLSNREYFFVKEMKDAKVLF
                     DRENISHIIKDISRDIYLEGPSKMSLEEKSFIKQDIGAKILNLKNKEKFDVFEYHFLT
                     NLYLKDIIIGYFNINDKWVPKDKKLLKVLKKENNELFELVSKVSENYDYQRLLDVYNY
                     IFKEIETKEVIKLIF"
     gene            19013..19585
                     /gene="folE"
                     /locus_tag="KR231_001522"
     CDS             19013..19585
                     /gene="folE"
                     /locus_tag="KR231_001522"
                     /EC_number="3.5.4.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP cyclohydrolase I FolE"
                     /protein_id="HBH0003904.1"
                     /translation="MNKVDKEKIQHAVREILEAIGEDPDREGLIETPNRVARMYEEIF
                     SGLSEEPRDHLKVLFADEKHEELVLVKDIPFYSCCEHHLVPFFGKAHIAYLPKGGRLT
                     GLSKLARVIDTLAKRPQLQERITKNAADIIMEELQPYGVLVVVEAEHMCMTMRGVKKP
                     GSKTVTSAVRGIFEKDIASRAEAMSLITMK"
     gene            19649..20440
                     /gene="folP"
                     /locus_tag="KR231_001523"
     CDS             19649..20440
                     /gene="folP"
                     /locus_tag="KR231_001523"
                     /EC_number="2.5.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydropteroate synthase"
                     /protein_id="HBH0003905.1"
                     /translation="MFDYGKRTYIMGILNVTPDSFSDGGDFNNLDIAIQHAKDMVDQG
                     ADIIDLGGESTRPGHSYVDSDEELRRVIPVIKKLKQELDIPISIDTYKADVAEEALKL
                     GVTMVNDVWGLRKDKNMASVIGKYDAEVCIMHNQDGTNYDKDIMESIKDFFKVSIEMA
                     MSCGVKKEKIVLDPGVGFGKDFEQNIEVLRRLNELKDLGYPILLGTSRKSVIGKVLPV
                     EPKKRLEGTIATTVLGIRDGVDIVRVHDVYENLMAARMTDAIYRK"
     gene            20451..20816
                     /gene="folB"
                     /locus_tag="KR231_001524"
     CDS             20451..20816
                     /gene="folB"
                     /locus_tag="KR231_001524"
                     /EC_number="4.1.2.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889257.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroneopterin aldolase"
                     /protein_id="HBH0003906.1"
                     /translation="MDKILLSNLGFYGYHGVLKEENFLGQKFFVDMELYIDSREAGLS
                     DDINKSVSYAEVYNVVKDITENKQFNLLEALAENIAEEVLNKFILINGVMVRVRKPEA
                     PVNGIYDYFGVEIRRTRDE"
     gene            20809..21315
                     /gene="folK"
                     /locus_tag="KR231_001525"
     CDS             20809..21315
                     /gene="folK"
                     /locus_tag="KR231_001525"
                     /EC_number="2.7.6.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-amino-4-hydroxy-6-
                     hydroxymethyldihydropteridine diphosphokinase"
                     /protein_id="HBH0003907.1"
                     /translation="MNKAYLGIGTNMGDRFDNLSRACELLKNSDSIYKVKESSLYETK
                     PWGYTEQADFLNMCVEIETEFEPYELLEYCQEIERELHRERIVHWGPRTIDVDVLFFN
                     DVVSTDERLTIPHPRIQDRAFVLIPLMDLNEELIINEKTIKEHLNLLSAEEREEVKEL
                     VGYERKPI"
     gene            21296..22081
                     /gene="aroF"
                     /locus_tag="KR231_001526"
     CDS             21296..22081
                     /gene="aroF"
                     /locus_tag="KR231_001526"
                     /EC_number="2.5.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-7-phosphoheptulonate synthase"
                     /protein_id="HBH0003908.1"
                     /translation="MKENLFNNNSKIEINTNNKKITVKKDKLIIAGPCAIESYEQLLE
                     TAKFVKSQGANILRGGAYKPRTSPNSFQGLKKEGLEILKAVKDEVGMAVITELMDVRD
                     MDELYSISDIIQIGSRNMQNFTLLSEVGKQNKPVMLKRGIASTITEWIGASEYIAIEG
                     NSNIIMCERGIRTYNDYTRNTLDLAAVPIIQKETGLPVVVDPSHATGVRYLVKPMSLA
                     SFACGADGIMVEVHPDPENALSDGAQSLCFNEFEDLMKSINNY"
     gene            22336..24126
                     /locus_tag="KR231_001527"
     CDS             22336..24126
                     /locus_tag="KR231_001527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA primase"
                     /protein_id="HBH0003909.1"
                     /translation="MNDIKDIIEEIKARCDIASIISEYMNIKQSGANYKGLCPFHGEK
                     TPSFYINTSKQIYKCFGCGEGGDVINFVMKMENLDFMDAVKILANKCGIEINTNMNEE
                     TRIKIEKSKKFQDIHTEAARFYLSNLLGSKNLGYEYLRIRGLDDKIIKKFGLGFSLDS
                     WNSLMNTLISKGYKKQDLLECGLIAKNRDGTNCYDKFRNRVMFPIFDYRGNIIGFGGR
                     VLDDSLPKYLNSPDTLIFNKKQNLYGLNFARKNLESKTIVLVEGYMDLISLYQYGIKN
                     VVATLGTALTEQQGILIKRYADTAIISYDSDEAGIKATLRAIDILTKLGINVKVLDLK
                     DAKDPDEFVRKYGLSDYKKAMDVSTHYIKYKIDHLKKEFNIQKDEERVKFAKEASKII
                     KQLTSPVEIDFYTKYLSNQIDINVESIKREVYGKNYNKPYNNKNQKKIEEKVIEKVEV
                     RQDGKQLVEETLIKIMLEDKKIREIALLKVEESDFLLKESKEILNYMIKNQELDKITI
                     DKLKSLNISEEYLKELNSISLNSINLENTKEIEGIITNIRKNSLEEQINSLLREQQEL
                     ENNNDMKEVDGRVMEIALKIVEINKILKSL"
     gene            24144..25310
                     /gene="rpoD"
                     /locus_tag="KR231_001528"
     CDS             24144..25310
                     /gene="rpoD"
                     /locus_tag="KR231_001528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor RpoD"
                     /protein_id="HBH0003910.1"
                     /translation="MENKSNKKELKKVTAKTLIEKGKKQGSLTLAEIMEAFSETELDK
                     DQVENLYETLGNLGIEITETKNYKADIDFSVADDDLSIGHLDEDAEAISHDDSSAIEI
                     ETVDLSLPKGISIDDPVRMYLKEIGKIPLLKPHEEVEFARRMHEGDEIAKQRLVEANL
                     RLVVSIAKRYVGRGMLFLDLIQEGNLGLIKAVEKFDYTKGYKFSTYATWWIRQAITRA
                     IADQARTIRIPVHMVETINKLIRVSRQLLQELGRDPKPEEIAKEMEMTEDKVREIMKI
                     AQDPVSLETPIGEEEDSHLGDFIPDDDAPAPAEAAAYSLLKEQIEDVLGSLNDREQKV
                     LKLRFGLEDGRARTLEEVGKEFDVTRERIRQIEAKALRKLRHPSRSKKLRDYLD"
     gene            25475..26164
                     /locus_tag="KR231_001529"
     CDS             25475..26164
                     /locus_tag="KR231_001529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAM-dependent methyltransferase"
                     /protein_id="HBH0003911.1"
                     /translation="MKLTDRLLKIASLVSDGKKIADIGTDHGYIPVYLLKEGKVPFAV
                     LADVNKGPLDNAHKEVIQNNLLDKVDLRLGSGIEILEIGEVEEVIIAGMGGILISELL
                     EAKKEVAHNVEKLILQPMQAQEELRYYLLNNGYEILEEVLVREDFRIYEIIVAKYTGK
                     NTIIEDEIYYEVGIKLLENKDSLFNDFIEKKIKTYSSIVNKLEGKNGEAIDKKRKESE
                     VAIKKLENLIK"
     gene            26178..27275
                     /locus_tag="KR231_001530"
     CDS             26178..27275
                     /locus_tag="KR231_001530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Nif3-like dinuclear metal center hexameric
                     protein"
                     /protein_id="HBH0003912.1"
                     /translation="MLLKSLTRKIEKKYPLNLAEDWDNVGLIVGDFDMDVKKVLVSLE
                     ANEDVIDEAISKNIDLIVTHHPFIFGKINKINSGDLKGRLIQKLIKNDISLYSMHTNF
                     DIAFDGLNDYFMEIMEFGNSKVLDITKSENLYKLAVYVPHNYSDELRKVLSNSGAGHI
                     GNYSDCTFSIEGEGQFKPLEGSNPFLGSVNDIETVNEVKIETVVPQKLLGGVISSMLD
                     AHPYEEVAYDLYKLENKGEIFGLGRISKLDKSMTLESLSRKIKEKLNMKHIRVVGNLS
                     TDITKVAVVTGAGSEFVKKAKRQGAEVLITGDVKYHEAQDALDIGMCIVDCGHFDTED
                     IFKNVMKRFLDEFSEIEVIKSNVYLNPFSTI"
     gene            27338..27910
                     /locus_tag="KR231_001531"
     CDS             27338..27910
                     /locus_tag="KR231_001531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896380.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HBH0003913.1"
                     /translation="MKVAVIFHSVCGSTYLLAREYKEALEEMNIEVDIFRVSDEVAKT
                     LPQYYLINSKEYKDEFESINVIKSGKEILDYDAIFMGSPTYYGNVSGPMKMFMDSFSD
                     IWVGTPLSGKIFGCFATAGSQHGGGELALQAMNIFAQHMGMTLLSVPCSVRGGYPAYG
                     ILHIAGDNSDIRPNDDAKIGIRDYLKRLNI"
     gene            complement(27970..28437)
                     /locus_tag="KR231_001532"
     CDS             complement(27970..28437)
                     /locus_tag="KR231_001532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxamine 5'-phosphate oxidase family
                     protein"
                     /protein_id="HBH0003914.1"
                     /translation="MFKEMRLKKREMTKEDTVEVLKNGEFGTFSTISENGYPYGVAVN
                     YVYFNDSIYFHCARNGHKLDNISKNNKVSFLVVANESVIPDKFSTTYSSAIVFGKACT
                     VENEEKKNALVEIIKKYSKGFFEEGMKYIEKDMNLTTVVKIEIDHISGKASRL"
     gene            complement(28823..29299)
                     /locus_tag="KR231_001533"
     CDS             complement(28823..29299)
                     /locus_tag="KR231_001533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HBH0003915.1"
                     /translation="MLSKAEIKYFNECASEILSSEKVQLMRTFPHHGNVSCLEHSLSV
                     AYYSYLLCKKLHLSVDIQSVIRGALLHDFFLYDWHYKGDRKGLHGFTHPREALKNATL
                     FFQINEKETDIILKHMWPLTVKPPRYKEAFIVCLLDKFCCLVETLKIHSLLSPYHV"
     gene            complement(29419..30510)
                     /locus_tag="KR231_001534"
     CDS             complement(29419..30510)
                     /locus_tag="KR231_001534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1648 domain-containing protein"
                     /protein_id="HBH0003916.1"
                     /translation="MSKIECLFTIFPVLILMYATFYFMPYFVGKKHIYGVSIDQEHKN
                     YNYFIKLDKEFKKLLSLGFIIDFILVFILVFTFNKLELSYFIGIIGFLLYESILYIHT
                     HKKAKKLKSEIYSKLGHIDIDSKLIVDMDFINKKNKIIKKFKIIYLIPILFTLGMSIF
                     IAFNYNQLPDSIATHWNINGSPDVFIDKSFLNVFKLIGTDFCLMVLLYITSIGSIKSR
                     IKIDTNRIEESRVENIKYLNKIGYLFLILMIIMTTQFFTTLLSIKTKLSTAMNITTLL
                     VIIYLIATYINSPNLKFNSSYSPEEDEKYWIAGIMYNNPNDPSLMVNKRFGIGWTINF
                     GNPLGKILYIAIALLLIFSLFSLIKSLLL"
     gene            complement(30503..30892)
                     /locus_tag="KR231_001535"
     CDS             complement(30503..30892)
                     /locus_tag="KR231_001535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBH0003917.1"
                     /translation="MVLNLDFNSDKSIYVQIKEEITKAIASGELKINESLPSVRSMAE
                     NIGVNLHTVNKSYNELKEEGFLNIDRRKGAIVAQLPMKIDNTTRQKNKLDLELLVAKS
                     YLSGISKEEFLSLSSSLFDKYEVKYYE"
     gene            31084..31530
                     /locus_tag="KR231_001536"
     CDS             31084..31530
                     /locus_tag="KR231_001536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0003918.1"
                     /translation="MLTYLMKRQMHKKDDGMSKPMMITGAVITGVGAYAVYKMVKSHK
                     SNSQMVNTNYYGNSDYDDYKYDEFDYDCDCRDTKQDYEYEELKKKVKEFNSRRINCEN
                     CPHVSQEEMMQYVNSVKDVKEEIDLHEDAKKDNIYKEDEYKKYEEE"
     gene            31794..32519
                     /locus_tag="KR231_001537"
     CDS             31794..32519
                     /locus_tag="KR231_001537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBH0003919.1"
                     /translation="MKRKEIVMLKLLIVEDDSTISFGIKYALEQEGFSIDISKDLSSG
                     KEMISSNEYSMILLDVTLPDGTGYELCQYIRGFSQVPIIFLTACDEEVNIVMGLDIGG
                     DDYITKPFRIRELISRIKAVLRRKGNTSEENKKILKFGDLSIYTLEARVYKNDKEIFL
                     TSVEYKLLLILIQNKNTVLSRTQILEKLWDVTYDFVNDNTLTVYIKRLREKIGDDLCE
                     PIYIETVRGIGYKWIGSENSVSI"
     gene            32506..33750
                     /locus_tag="KR231_001538"
     CDS             32506..33750
                     /locus_tag="KR231_001538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBH0003920.1"
                     /translation="MFLYNPEVKKFLSKYVTLMFIVIIISIGFSIINVSLTKEMVVRN
                     NQAIIGTLSSKYPNLESQIVDIITQGKSMENIDYGQKILIKYNYDKSIRINSEPIISK
                     LVLETIKINIILVCIIFILIFVLVVRYFKSIYNDLSDMTKYVYYSSEGKPFDMKNKNQ
                     EGQIGLLKTELLKMTTILNEKVELLKREKIFLNNTISDISHQLKTPMTSLIMLNDLLY
                     NDVPYEVKIDFLNKIKNQLNRMDWLIKSMLKLSKVEAKVINFKKDKVKFSELIHRAML
                     SMKIPMEIKNQKLTIEGNDNVSYIGDIDWSVEALVNIIKNCVEHTPEFGNIIITYKEN
                     PLFSELIIKDEGEGIDKKDIPHVFKRFYRGRSSSKEDSVGIGLAMSKSIIESQNGDIY
                     VNSEKGQGTEFHIIFHKMYDSD"
     gene            33830..34507
                     /locus_tag="KR231_001539"
     CDS             33830..34507
                     /locus_tag="KR231_001539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003517588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH0003921.1"
                     /translation="MEILRVENLTKSYGKNETKVDAIKNVSLSVEKGTFIAITGPSGS
                     GKSTLLHLLGGVDRPTSGKVYINDVDIYNLKTKDLAIFRRRNIGLIYQFYNLIPVLNV
                     KENILLPAELDNRDIDREYFDDLMKTLGLIDREKHLPNQLSGGQQQRTSIGRALINRP
                     SIILADEPTGNLDSKNSKEILELLKLSVKKYNQTLIMITHDKNMALQADRIISIEDGI
                     IKSDEVM"
     gene            34508..37069
                     /locus_tag="KR231_001540"
     CDS             34508..37069
                     /locus_tag="KR231_001540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBH0003922.1"
                     /translation="MNLYTLLTIRYLKQNKRRTIVTIIGIILSTALICGIGNIFESFM
                     DYQMRETIKNDGSFHVTFYDVNRKNVEYVTKSAEIEKHAFTKQLGYSKLENSENAILS
                     IKQYDKNAINGYKVSIKEGRFPAKEGEIVLSESIINLIDDKLKIGDKITLKVGDMFDS
                     SKKKIDSMTFHEGDYIANEKDRTFKVVGIIEKPGFERYNGIATAIAYFNPMNNYNDTI
                     NVSVAVRNPKDVYKISNKISKNIYSNKDKEAVSDMIKYNEHLLRLQGASKYSNINNSI
                     KSIIIAVTILVIICTIATVYNSFSISINERKKQFGILNSIGATSSQIKRLVFIEGIII
                     SLIGIPIGLISGTVAIDLLFKIINKYFTESVVTKMSLQIVYNPIITIVSIIIVLLTIF
                     ISILLPAISASNISHLNVIKNTGEYKVGKIKSSRLIKMIFKTEGVLAYKNIRRNRKKF
                     IITLFSLMVSIIIFISFSGFTLLLLRGEEIRNSQRKYDLYLTAKNTARSVEDTISELE
                     DIDGIKNFELATGQYVSIRVSENKINKSKEDLIRKYYQKYKIGDSYEYDFSNNELIFP
                     GDFAVKNKINNLVQGSFNKERAIEENGVILVRKSAFEENGKKGVVELTNYKVGDTVNC
                     EYLDENALSKKVKVKILAITDEERLGLGYQNMGLQFITYDEVAKNLNLKLSKSLIFID
                     SGGSIKTKKEIEALANKNNFNFYDESASNESEKQDLKVIKIFVYGFIVVISLVSVTNI
                     LNTVSTSINLRKRELAVIQSIGVTPKGFRKMIYLESFIYGILSLLFGIPISIGIILIM
                     NKLISGVIEFSPIIPWTAIVICIVSVFIITFIAGYIPMSKLNKENIIDNIRRESI"
     gene            37260..38534
                     /locus_tag="KR231_001541"
     CDS             37260..38534
                     /locus_tag="KR231_001541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S dicluster domain-containing protein"
                     /protein_id="HBH0003923.1"
                     /translation="MITISHITAKNMYKSLEERINKFPQGAPPSDTLYKILNVLYTEQ
                     EAKLVAQLPIKPFRVKTAAKIWSVSESEAYRVLDKLASKALILDIEDNKGKKYIMPPP
                     MAGFFEFAMMRTRHDIDQKLLAELYYQYMNVEEDFIKDLFYSTETKLGRVYVQEEVLT
                     NDNEVSILDYERATHIIDESTHIGISMCYCRHRMQHVGKACDAPMDICMTFDNVANSL
                     INNKFARRVDKIECKELLHQAYEHNLVQCGENVRKGVTFICNCCGCCCEAMVAAKRFG
                     NLHPVQTTSFIPNINHENCVKCGKCITACPIDAISKVKEDGKEYIKIDEDRCLGCGVC
                     VRNCHKNSIMLLKRDEKIITPANSVHRAVLMAIEKGQLQNLIFDNNALASHRAMGAIL
                     SAILKLEPAKKILASKQLKSVYLDKLLSMNDK"
     gene            complement(38695..41736)
                     /locus_tag="KR231_001542"
     CDS             complement(38695..41736)
                     /locus_tag="KR231_001542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp20"
                     /protein_id="HBH0003924.1"
                     /translation="MFKQRLSKLLSSTLVLSMLFTAAPNITFADNTKDNSEKYQSSDI
                     ELHDYSKNAESYTKTKALAKEKIQTLLSKYGAVSAQYALIDNGKIEISGNGGVYSKQD
                     NKNLNKDNMYSIASISKMFTTTAVMKLVDDGKLNLDTPVVKYIPEFKMADDRYKEITP
                     RMLLNHSSGLMGSSFKNTILLADNDSYGHDNFLKELQKQRLKAKPGAFSVYCNDGFTL
                     AEILVERVSGMSFTNFLDKYINNPLNLQNTKTPENSFDSSKLAKAYVPYWEDAVPQDN
                     LNAIGAGGLYSSAENLCTFAQTFMKNSNGILSPASVKAMENKEYLNGLWPEGEDSILG
                     YGLGWDCVNTYPFNQYNLKALTKGGDSLLFHSNLIVLPDENMAVAVLSSGGSSQLNEI
                     IGQEILLSALKEKGKIKEIKPDKTFSKPQQVKMPSSLKENSGLYASSNMIKVDVNDNG
                     TLTVSSPYIENGPEDKYVYIGQDRFVSEKGNSCLKFVKEKNNITYLNMSSYDDVPGLG
                     QTASLYYVAQKVDDNNISNSVKEVWKKRSGKGYYLVDEKYTSQSYMFGSVKASFSLSD
                     ETPGYIVNTKIMDENNSNAFIEIPGVIGRDLSDIKLHKENGTEYLSFGTLTYVSEDSI
                     TNLPAEKSFTCELESNGYAKWYKIGDDIANKKIEVNLPQNSAFAVYDDKGVPVNYSLV
                     TKNNRVRLPKGGVIVFLGSPNARFEVTYQDEVNASALTGTDRYETSIKISQAGWENAE
                     NAVLINDSAIADALAATPFAYKKNAPILLTGSSQINEKTLAELKRLKVKNVYVVGGEA
                     SINEKSLDTIKSNNISVSRISGSDRYQTSMNIAKELNNISNISKISVVNGEKGLADAV
                     SIGAVSAQNDMPIILTNENSNITEINNLFKNKKIDKSYVIGGEYTVSKNIESKLQNPQ
                     RISGSTRNETNAKVIKEFYKDSKIDNLYVAKNGMNKQDDLIDGLSVGVLAGKTKSPVM
                     LVGNSLDYNQKELFKTMRFKSVTQIGGNGNENSFKQIKEIA"
     gene            41943..42242
                     /locus_tag="KR231_001543"
     CDS             41943..42242
                     /locus_tag="KR231_001543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HBH0003925.1"
                     /translation="MYKNINKKQLKEMMKNEKDVLLLDVRTKDEFKEYKIENAINISL
                     QELINNIDEIYDYKDKKVVVYCRSGHRSVTACNLLAEEGFEHLYNLNSGIIDYMS"
     gene            complement(42480..44708)
                     /locus_tag="KR231_001544"
     CDS             complement(42480..44708)
                     /locus_tag="KR231_001544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhgE/Pip domain-containing protein"
                     /protein_id="HBH0003926.1"
                     /translation="MRHLKKTNSLKEILNWNNIKNLRPSKGLKNILEIFKSDLKDIRG
                     NYAVLVIVLGLAFLPSLYAWFNIKASWDPYGSTANMLVAVTNEDKGNEIAGQKINVGD
                     QLIEQLKDNKSLGWQFVDEKTALEGVKKGTYYASLKIPKNFTKDLTSLITDDVKKGEI
                     IYTVNEKINAVAPKITDKGASTIQLQVNQTIVKTVSEIVLGISNGVGAGIEHSLPKLT
                     KVENSLIDLQKRFDHINKTVDLASDATSKLSDTVKDIKSDLPTIKKTLNDTKLLSSDL
                     KKFLEDTNDNLDELSPLIKSDLNLMVDLSSSASSLTLNLIDAVNSGSEDVPKLIDNLS
                     EKLSNLQSLNDTLVDFLTKLNQLTSNNRLDDVIDNLEDSSNKIDSSISTLNDIKNKVI
                     SGQQPSISALNNVLSLSNGIGRINLNILNNFDSKISKPINSIFANSIKVANDIITVLD
                     KAEAKLPKVEEILTTSLKLSGNAQESISLIRERLPLAKGMLDDLIDTLSKISNGEDMK
                     KLVSLLESDILTKSNFLKEPVEVKTEKLYPIENYGSAMTPFYSVLSTWVGILLISALL
                     STSVHGNYKPYEIYFGRGLTFLSIALVQGFIIGTGDILLLGVTAKHPILLIVLLMFTS
                     MVFNFIVYSLVSVFGNVGKAIAIVLLVVQIGSSGGTFPIQVTPTFFQRINPIMPFTYA
                     IGATREAVGGIYAPNLTKDILVLLLFMILSICLNVLLKGPINRVIKPFNDKFGDSNLT
                     GH"
BASE COUNT        17816 a         4873 c         7484 g        14634 t
ORIGIN      
        1 tatgcaagga tagttgaaat tgataagaat tataatgact ttgaatttcg agtagtgcca
       61 ttaaaaatag cagatttatt tgaagaaaat attttatctc aattagaaaa aggaatattt
      121 ttatcagcaa ctttgagttt atctgaaagt atgtcttatt ttaaaaatac attaggaata
      181 gacagagtta agaatgtgga aaagattata gaaccaattt ttgattataa aaatagagtc
      241 tctgtagttg gattttctga tatttgtgag tacagaaatt ctgaatttcc aaatgagatg
      301 agtaaaatta tatctaatat atcaaagatt acagaaggtc atacattagc tctttttaat
      361 agtaaagata gacaagaaaa aacttatgaa atattgaaaa aatacttaca tagttttaac
      421 ttagaaattt atgctgataa aaaggggatt agacacctta acgatttaaa tagaaaatgt
      481 gtagtacttg gctcaaaagg atgttttgaa ggcgtagaca ttccagggga tggtttggtt
      541 tgtgtaactt tagacaagct tccgaatcta aatccaaaag accctttgta ttttactata
      601 atgaagaagt atggtataga ctactatact ataaattatc ctcaaatgac cataaaggta
      661 aagcaagcta tggggagaat tttaagaagc aaatatgact atggatgttt tgtgattttt
      721 gatgtaggaa ctaatataag tgtgttaaag agattagaga aagatttaca cgattgtaaa
      781 atttcaaagg ttaatagcaa tgagttttat acttatataa ggcgacattt aaataaatat
      841 agaagtttaa tactaaaatc tgttatattt gatactataa aagcgttgaa tgttgatgct
      901 aaaatggata acaatgatgt tgataaggat attataaaaa aagatataaa tgaaaatata
      961 agacaaagag ctgtaaaagg agaagtgtac catattgata ttataaaaaa agatatgaaa
     1021 gtaaaatatt ttgatagaaa ctatcttata aatttagata tatttatgag agaagaagat
     1081 aaaaattaag agtgggagtg atatatttgg caaaacaaaa gttttatgct gtgaaaaaag
     1141 gtaaaaatat aggtgtatat aatacatggg atgagtgcaa aaaacaagta aatggattct
     1201 caggagctga atataagagt ttttctactt ttcaagaagc taaagaatat attgatgggt
     1261 cagaaaaatt gagttttcaa gaagataagg agtttataga agcatatgta gatggaagtt
     1321 atgaacattc agtaaaaatg tatggttcgg gtgttgtgat tttaaaaaat aatgaagtta
     1381 taaaaactta tagtgaaaaa ggaaaagaga aaactttagt aagtatgaga aatgtagctg
     1441 gagagataga ggcttctaaa attgcaatgc agtactgtat tgacaataat gttcaaaact
     1501 tgattttata ctttgactat gaagggattg aaaagtggtg tactggagtt tggaaaacaa
     1561 ataaagaagg aactatagca tataaaaatt tctatgacag tattaagaat aagcttaatg
     1621 taaaatttac aaaggttaaa gctcattctg gaaataagta taatgaggaa gcagataaat
     1681 tagctaaaaa agctattggt gtataataaa aaaatattta tacataatta catggtataa
     1741 gagtatatct aaattcctac tttataatta aacaacttgt aattaaacaa cttgtaatta
     1801 aacaacttat aattaaataa attttgatta aaaaagcaga ttgtattatg aaaaaataag
     1861 tatctaattt ataaacaatt aataatagta ttaattagat acaacttatt taatataata
     1921 aaatctgctt tttatataac tataaaattt tcctacattc tattagaatt gcccataaat
     1981 accttcaagt tcttctttta atacttcagg gtcatttata ccaatagaca tggttctagc
     2041 cagtatattt gcttggtcat aagttgatgt ccatgagaat acaccaccta gacaatttct
     2101 aagaacatat tgagttttta agaatattga taaagcatca tcatatgaca ttgcaaaatc
     2161 tccatcctta actaaatatg gaacttgagc agtattatca aatctatatt catatccatt
     2221 tttatttata taatcccttc taagctcatc ataagttctt gttatagtag cacctaatct
     2281 tccataaaat ggtataccaa gaaggatttt ttcagaaggc attccagcat tctcaagatt
     2341 tcttaccatt gcatcaacac tatatcctgg caaagataag tctgaatcaa aaagatttgc
     2401 ttgatgtttt ctaccatttg ggcctgtttc acctgctgta aaatcataac tcataagatt
     2461 aaaataatct attataggag ctattttatc tatttcagca cttgaattta tatatcctct
     2521 atctcctgtt ccagctacac taagccattt atcatctcct ataacatctc ttatggcagt
     2581 tagtaagagt gtaaagtttt ctctatcttg aggtcttgat gttattccag atgcactact
     2641 tccaggatat tcccagtcta tatctattcc atctaaagca tattcattta tcatctgatt
     2701 gacctgtctt gcaaaattat atctagatgt aggtgttaat gctgcatcag agaatccttc
     2761 agctccccaa cctccaatag ctacaattac ttttaagcta ggtttttcac ctttaagagc
     2821 aagtaattga tttaaaaatc taggataagg aataaacaaa tttccagact ggtctatctc
     2881 agcaaaagca aatataactg catctaatag ttgagcatct acattagttg gatttccaag
     2941 aacatattct gctacaattg gatttatatc tggacagttt gcattttcaa ctattggatt
     3001 gtatgggtct gttatttgtg gtctaactaa ttttttagaa tcttttaaag ttttcatagc
     3061 tattttttta gtattttttt cgctagtata atcgtagttt ttataattat gtttatagaa
     3121 atcttcataa ctactatctt ctttgttata gctagaattt attttgtcac aagattcatc
     3181 tttatcatag ttaaaattca tttcatcaca agacttatct ttaaacttat cttgtttgga
     3241 gttgtgaact ttgttagtat ttttagtatg ttttttctca tgattgcaat catctttaat
     3301 atcagtcttg tgttcttgtt tacagtcaag agctttgttc aggtagtcat gatgttcatg
     3361 ttcacagtta cattcatttt caatgttttt agtatgttct tttttccagc tacaagtatt
     3421 atcaattttc ttgctcactt cttcatcatt ataattatct ggtacaaaac ataagtacca
     3481 gtccatacat gaatatttct tattacaact gttaactcta ttttttaatt ccttatagtt
     3541 tttaggataa ggtaaaatca ctggcattcc aggaaaccag tttgcaggag taactatatt
     3601 atctctatca ctagtctgaa gtgcatctac tattctaagt atttctggaa tatttcttcc
     3661 tgtagttagt ggataataaa gaatcgttct tagaatttga ttattatcta taataaatac
     3721 agagcgaaca gttgatgtat cactcattgg ttttgatatc atgccgtata acttggcaat
     3781 tctcatatct ctatcttcta taataggaaa tggaatttct acacctgtaa gtaaagaaat
     3841 attatacatc caagctaaat gtgaactgtt actatcaaca cttagaccaa ttagttctgt
     3901 atttcttttt ttaaattcgt cataatattt agcaaaacat aaaaattctg tagtacaaac
     3961 tggtgtaaaa tcaccaggat gtgaaaataa aacaatccaa ttacccttat agtcagagag
     4021 tctaatagga ccatttgttg tattggcttt aaaatcagga gcctttgacc ctaaacttgg
     4081 caaatttggc atgtaaatca cccctcaata aattatcatt tattttattc tattaattaa
     4141 tacatattag tgttactatt ttattaaaag ttaagtaatc cttatgtcaa aaaaagatat
     4201 ttattaaaaa gatttaatat tttcctaata taaatgacaa tagtaattgc tattttttta
     4261 ctaatttggt atagtaatgg ataaggggta gtgtcaattt tagtgattat acgaggtgag
     4321 tggattgaaa aaaattctaa gaattttagt tatctccatg atgatatgtt ttgcaatgac
     4381 ttttgcatta gtgttaataa attcagttat gggagtacat ataggattgg attattactt
     4441 tttgatggga agtgtgctta cagtttgttt aacaattgga attgttttat gcaatgctag
     4501 aaaaatattt gatagcaaag ctatacacaa gacaagaacg aaaactgtca gtaataataa
     4561 aaaacaaaag agtcattcta gggatataaa aagaaagata tcataattta tgtaaaggaa
     4621 atatttatgt ataaaataat gattgatagg taaaataaaa acacgattta acttgtgttt
     4681 ttattttttt tcaagaatta tgatataata accaataaga aatttagttt accataaaat
     4741 ataaagatta ttaaatggag agggaactat aatgaatttt agagatttat ttgagaaggc
     4801 tgtagatttt attgatgaaa aaaggaaatc tatagttgcg atttcattat caacattagg
     4861 tgtaattgct ttgataatag tatttttctt aagtagtaac gagtttagtg taggaaatga
     4921 agctaatgag ttgttaaaga ttatagagaa aagacagtat tctatagctg ttgattacta
     4981 cacaagtata gaaaaaaagt tttctgattc aaaaatggaa aggtttaata agtctgtttc
     5041 taaaaaaata aataaattgc tattaaatag tggtgataaa tatttagatg gagacataag
     5101 tcaagaaagt tttattggat taataaatac cgtgaaagaa ttaaacaaaa taagtataga
     5161 tgtggatgac ttattagctc aagctgatag agttagagaa atgtataaag aagaaaatac
     5221 tacttatgat attgccatta actacataag tactgtttca atattaaatg gtatgggtag
     5281 taacctagat gtatacaaac agaatataga aacaatcaaa gagtctagag atgtttatga
     5341 ctcagcagta aaagaccaaa aagcatataa gtattatgaa gctattgaaa agtataataa
     5401 agtattaaaa gaagatgaaa agtattacag tatggctcaa aatgggaaag aacaatgtat
     5461 tgaagaaatg tatgattact atataagtag agctgaagag gcaaatactt ctggagatta
     5521 tgaaagagca ttacaatata ttgagtattt aaaagacgat tattcagatg atgaaaaggt
     5581 acagagttta gaaaaaaaat ataaaaagaa tttatcattg tatactttaa catctgatga
     5641 cattataaat gtaatagcta aaaaaagtgg caaagacaag gcaaatctat ctataaattc
     5701 acttccacaa atgataaaaa ataataaata ctattatgct gaagtatatg agtatgataa
     5761 attaataaat gaagttttgg taagtgcaaa aactaaagat ttatattcat ataaagatgg
     5821 taaaaaagat tacaaagtag attatggtga tggatacttt agaatattag aagatggaag
     5881 ttatcaattt ggtattacaa aagataaagc taagtttgtg ttaactaata ctcttgatga
     5941 aaaagaaaat aagtataaaa agattgagat attagatata gagaaagcag atagatatgt
     6001 aaaaagtaaa aagagtttag aagaattgtt tggaaaatat aaaaatattt attattatgc
     6061 tgtagtaaat aaaggcttat ttagaggcaa agaagtttat gctattaata tttacaatga
     6121 aaaaatatat gccatatcag aaaatggact aaatgaatat taattaataa tattaaatta
     6181 atatataatt aaaaagtttt tggggtttta aggcgcatta tgtagtaata taataatagg
     6241 gatatataaa taattttatt gtaaggagaa gtatgggatg agtaatgtga acaaaaagct
     6301 agttatagct attggagctg tagcattagt agtaataatt tttataggca taatgtgcat
     6361 gcaatttaaa ggggagaaaa tagcaaaaaa cacatatgtt aatggagtaa atattggaaa
     6421 attaactaaa tcacaagcaa aacaggaatt agctaaaaaa tacaaattag agaatgttga
     6481 ttttaattac aatgataaaa gctggaaagt aaagagcaaa gatttaaatt tatctactga
     6541 cctggataaa acagtagaaa acgcatataa tttaaataga aagagtgctt tctttggcaa
     6601 tctatcaaaa actatttcag caaattttgg caaaaaaagc aacttagtag ttgcgataaa
     6661 ttatgataaa aataaattaa aagcagaaat ggaaaagata gctaaagaaa tagatgtaga
     6721 tgtaaaagat gctacacttg atataagtgg tgaaaaagtc aaggttatac cagattctga
     6781 tggtcttaaa atggatattt ctaagagtat ggagaatttt gataatcaaa ctaaaaaagg
     6841 taactataaa aatgagttag tagtaaaagc tactccagca aaagtaaaaa aagagcaact
     6901 tgctaatata gatacaaatt taggtacgta ttcaacaaca tttaaaactt ctcaaataaa
     6961 tagaagtata aacataaaat tagcaacaga taatataagt aatgtattac ttatgccagg
     7021 agaaactttc tcatttaata aacatacagg gaaaagaagt aaggaaaatg gatataaaag
     7081 tgcacctgta ataatggaag gtgagatgga agaagattat ggtggaggag tttgtcaagt
     7141 ttcatctacg ttatacaatt ctgtgctata cgcaggttta gaaattgtta atgtaaaaaa
     7201 tcatactata ccatcaagtt atgttccaaa aggaagagat gcaactgttg cagatagtgg
     7261 aatagatttc ttatttaaaa ataatctaaa gcatccagtt tacataaaaa attacgtttc
     7321 aggaaatcaa attgtttgca atatatatgg aagtgcagaa gataaacaaa atataacaat
     7381 atcaacaaaa ttagatggcg tttcacaaac tacaatgaaa agagttaatg accctacaat
     7441 gcctaaaggt aaagaaaaag tagacaaaag tggaagaaat gcatattctg tatcaacata
     7501 tagaacattt aatgatgcaa atggtaaaaa aattaaaact gaaaaaatag ctaattcata
     7561 ttatcctaag aaggaaggta ttatattagt tgggactatg gaaccaaaac cagaggaaaa
     7621 accaaataca gacgaaaata agaataatca aaatacaaac aatcaaaacc caaataatca
     7681 acaaaaacca gaaacaccac caactgataa taagcctaat gagacacaac cacaaccgca
     7741 agcttaaagt tctcaagaat aggatttatg tagagtaata aaaaatataa atctaaatag
     7801 gagggattac tttgaattta aataatataa cgaattacgt tcaaagtatt tgcgagaata
     7861 tttctaatgt cttggatgta gatgttactt tagttacaaa agatttaact aggatagcag
     7921 gtacaggaat attcagaggt aaaataggag agacaatatc agagaagtca gtgtactctc
     7981 ttgttttaaa agatgggaaa tcctatgtta taaataaaga aatagaagag aactgtaata
     8041 aatgtgcaaa tagagaaaat tgtaaagagt tagctgatat atgtactccc gttaaaatgg
     8101 gagagcatat acttggaatc ttgggtatag ctgcgtttaa tgaagaacaa aaagaaaaga
     8161 tactttcaaa agataaggag ttaactgctt ttgtaaggag tatgtctgat ttaatatctt
     8221 ttaaactaga tgaactttat aaacaagaag ttaagactat agatgacctt gagagggaag
     8281 ctatagaaaa tgccataaag aaatatggaa gtaatacaga aggtatgaaa aaagtagctg
     8341 aggcattaaa tataggtata gctacactct atagaaaagt aaaaaaattc aacattaaaa
     8401 gttaatagta ttgaaaaaga ggtaaccttt ttatgaaaag aagaggatta ccttttttat
     8461 tatgagaatg gtggaaaaat atgtatagtt ttgacttgac atattaaata tgttatctta
     8521 aatatatatt ttagagtgga ggtgagtatt attttagtta aagatataaa acaagacata
     8581 gaaagcatgc ctagaaaaat tttagatata tctttgatag aagataataa aagtgatttg
     8641 acttttttta atatagaaga agaagacggt gatgaaacat taaaagcatt aaaacagagt
     8701 tatgtgacta caaattataa agaagaaact ctattaaact tgcaaggagc tttaaattca
     8761 aagtcagata caacgtctaa ggagttaaaa ttagaatcat ataaaagata taacaatgca
     8821 ttggatttag catataaaaa ttatataact agtgccatta atatggttaa taaagctctg
     8881 gagataaatc ctaaagacat tgatatacta aatcttagag gtcttttaaa attattaaaa
     8941 tgtgattttg ctaaatcatt tgagagtttt tatactgctt tatgttatga aaataatcat
     9001 atatctagaa aatatgtaaa tctaatttca tctgaagatt ttaaaacttt tttaggaaga
     9061 tacaatcatt ctataagatt tataaatgaa gaattaaatt atgagtcaat acatatttta
     9121 gagaacataa ttgaagaaga acctgaacta atagagccat atgtaatttt atctttgtta
     9181 tatgataaac taggtaatgt aaaaaagaga gaaggatatt tagacaaact taaagagcta
     9241 gataaagata atcctgtatt tgaaaaaaat gaagaagaaa aagaagatac aagtaaaaag
     9301 gaagaaataa aaaaagtaaa aagaaagaaa agtattttgc catatattat agttggctgt
     9361 gttttaatag gtatggggat atatttgatt caaagcaaaa agagaataga aaacttgaat
     9421 aaccaaataa gtagtaaaga ggaaaagtta agtgaaactg ataaaaagtt aggagaaacg
     9481 agtaaaaaat tagaaaaaac gaataaggaa ttaaatgagg ttaaaaataa agaaccagaa
     9541 agagagataa ctgtagctga tgaggaagat ttatattatc aagctctaaa tttaaagaaa
     9601 aacaaagaat atgaaaaagc catagataat tttaaaagtg tagtttcttc tggtaaaact
     9661 aaaaaatata tttctgagtc aatatatcaa ttagcaataa caaataaatt attaggaaat
     9721 aaggatgaag ctataaaata ttacaaaaaa tatataaata cttatactaa aaatgaccag
     9781 tattatgatg attcatatta cgagttgggt atgttttatt atgataatgg cgatttaaaa
     9841 aatgcacaac agacttttta tagtttgaga agtgaagttc cagacagtat gtataacaat
     9901 tcaaaaataa aagaaatttt aagtgaaaaa taggtttata tagttaagtt ttttgaaaca
     9961 accaagtatg tattttatta aattaaaata aaaataaatt taaaaagaga ttgtgtcaaa
    10021 ttataacttt ctattttaaa gaaagatatt tgcttgttga taaaactaca aatatatgat
    10081 ttgaagcaat ctctttaatt tttggaggtg gaaaatgaaa gttttcaatc aattggtaat
    10141 aattttatct atctgggtaa taggagagta tataagttcc tttatacaag gaattatact
    10201 tattcctggg agtatagttg gtatgctatt attatttcta ctactacaat ttaaagtttt
    10261 agacttgagt agtatagaaa atgtaagtgg atttttcctc gataatatgg ctatattttt
    10321 tattccagca ggtgtatcac ttataaagtc attagaccta ataagggaaa atgtattagt
    10381 gcttttatta gtcatatgtt taagtacact aatagtaatg tatactactg gaattattgt
    10441 ggagaaaatg ataaaaaaga aggaagaagg acaaaaaaat gtataatgta ttacagacac
    10501 cagtatttgg tataatagta acaatagttt ttttcaattt aggaagatac attcaacgaa
    10561 aaacaagtaa tcctatatgt aaccctttat taattgcaat cgtaggaata atattgtttt
    10621 taagcatatc taaaatccct tatgagaatt acaagatagg agctgatagt ctaaatttct
    10681 ttttaggtcc tgtcacagta gtacttgcag ttccacttta taaacaattt gaattattta
    10741 aaaagcatat gtttgagatt attgtaggaa taggttgtgg tatagtgatt tcttttgtat
    10801 ctgtattgat aattggcaaa atagctaatt cagatgtaag tataataaat tcactaattc
    10861 caaaatctat aacaacacca atgggaatat ctttagcaaa ttctttaaat ggtgtagaat
    10921 caataacagt tgtagccata atttttacag gtatttttgg tggtatggtt gcttctacag
    10981 tattcaaact ggggaatata aatcatccag ttgctaaagg aattgctctt ggaacatctg
    11041 cacatgcttt aggaactaca aaggcttttg aacttggaga aatagaagga gctatgagtg
    11101 gtgtttctat tggagtctct ggtacaatta cagtaatact aattccaatt ataatgaatt
    11161 ttatataaaa aataaaatta agatgagtac cttgaatact taaaacaaaa taaaataaaa
    11221 aaaatttaaa ataaaaactg aacgaaaaaa atgcaaataa tgaaataaaa aaatcatgta
    11281 ctgaaattat aaaaagaaaa atttcattta ggaattaatt ataaagagac aattactaaa
    11341 cttgaatttg ctaaaataaa ataaattact gctaaaatag atatttagaa aaaaatacta
    11401 taaatttact atattgcaag ttaaataata agcagtatca tattatgcta gaaaaagttt
    11461 catttaaggc ataaatgaga tgatttgaac gtttttaaag attagaatat aaaagattgc
    11521 actagacata tatgaaaaag ataatataat agatgatgta atagatgaca gttcaagaaa
    11581 ttataaaaaa aatttatttg aaatattatc tattacatca ggaataatat atgtaagagt
    11641 aagcttttaa aattctaaag atttagaaag attgaaggga gaaagaaatg agtgaagtta
    11701 agaataccct acaaaaacat ccagttttaa gatattcaac aatgctattt gggatgttga
    11761 tgacatctat aggaataaat gggttcttaa gaccagcaca tctgcttagt ggaggtgcta
    11821 caggtatagc aacatctata aactatttga caaatataaa tgtaggttta ttaacatttt
    11881 taatcaatat tccaatattt atcttagggt tcatatacct tgaaaaagag ttttgtattt
    11941 caagtttggt aaatatgatt gtattttcat tattattagg agcaactcag gaaataagta
    12001 atattatacc tatacatgat atattgcttc aaagtgtata tggtggtata ttatctggtt
    12061 taggagtcgg agttgtattt agaactaggt cttctcaagg tggtacagat ataatagctg
    12121 caatactaaa aattaagaag aatatagaaa tgaaagacac tgctttagca ataaatggct
    12181 tgatagtact tacaggaagt tttttatttg ggttggattt agcattatac actcttatag
    12241 gtctatttct aaatgcgtat tcaatgagtt ttattaaaga tgcaatgaat taccaaaaat
    12301 ctgttatggt aatgtcaaat gaagtcgatt taatagcaga agatataatg aagagtttag
    12361 ttagaggtgt aactttttta gatgcagaag gtgcatacac tcatcaaaaa aagaagatta
    12421 tatatacaat agtttcatca aatgagatac caaagataaa agatatagct ttgaagtatg
    12481 ataaaaaggc ctttatatct gtaaatgatg ttacagaagt aaagggaaga gggtttaaag
    12541 caaaagattt atagaaaatt ttacaagctg ggagtttata atgtaaattt gtatattata
    12601 tctctcagct tatttaaatt tagtatacga aaataaaggt tttattaatg atttgtgtat
    12661 cactttaaaa gatatcattt taaaattaaa attgaaaaaa ttacttaata tgtagaaaac
    12721 atgaccacta ttaggatata ataaatttaa tagatttagt aaaataccta ggaataacgt
    12781 tggaggaatg gcattatgaa tttatctaaa gaatatgtta atttgtatga taattatttg
    12841 aaatatataa atgaagtaaa caaagagatt agaagtataa agaacatgaa gaaacgtgtt
    12901 ttaaaaaggg gcgattttgc tccggaaaat gaagtattag aattggaagg aaaaacaata
    12961 cgcgatatag atgatgtcga tacaaaaaaa ccaaaaaata aaatctataa attttcaaat
    13021 ggggatgtat atgtagggaa attcttagag ggaaagatgg aggggaaagg ctcatatact
    13081 ttttttgtag atgaaggaac agttatggag tacataggag aatttaaaga agataaaaaa
    13141 aatggaaaag gaaactttat attttcaaat ggaaatgaat atataggtta ttttgaggaa
    13201 gatatgatga gcggtattgg aaatatgtta tatagtagta aagatgaata tattggaact
    13261 tggaaaaacg gaaaaaaaga tggaaaaggt atttataagt ggagtgatgg atgtatatat
    13321 gcaggtgaat ttaaaggtgg aaagatggaa gggtacggta tttgctataa tagtaaaggg
    13381 gaagtacttt atgaaggaga atggaagaat aatttgattc atggtaaggg aacttatata
    13441 tgggaaaaag gtaaaaagta tataggtgaa tttatgcatg gtaaaaaaca tgggcaagga
    13501 actttttatc taaataatga attggtttat gaagggactt ggaaatttga taagccatct
    13561 atatttgata gaacattaga tgaaatattt tccttgagac tgtagcttta tctaattagt
    13621 agataaagct tttttctaat acttactgta aataggtatg aatgatattg attagtatac
    13681 actatcaata ttaacttaat aaatgcaata ttaaaaaatt ttgattgatt ttaagaagga
    13741 gagatatatt gaagagatta attgctttag tgttagtagt acttattgtt ttattttata
    13801 gtcctgaatt attaaaagaa ggatatgatt taaaagaaaa gttttttcaa agtgaaatat
    13861 ggaatgaatt tttagacaaa ataaatataa atgataattc taagaaagat aaaaaagaaa
    13921 aaagtcaaaa tttacaatca aataatactg aaggggagaa cttaggagag tcagatataa
    13981 agaattttga aaaaataagc ttaggagata atttaagcta tgttttatca agtatcggca
    14041 aacctggtag aattgatatt agtgaatatg gttttgattg gtatgtatat aatcaatatg
    14101 gaaaagaatt tgcaatggtt ggacttgaaa atgatgaagt agtagcactt tatagtaatt
    14161 ctattaattc atgtgaaaat caagatataa aactaaatca agatagacaa acagtgagaa
    14221 ctaagattac accattaaaa tataagagaa aaggaaatac cagatatata ataaactcag
    14281 aaaatcaata tgatataata agtaaggaag gtaagtatat tacaattttc tacgatattc
    14341 atgaagaaaa tagagtttgt tcatatttaa taattgataa aagcactgaa gatgagttta
    14401 aaaatttata tccagatgat agcgaagaac ttaaaaaatg ttttgaactt gaagttatag
    14461 accttgtaaa tagtgttaga aatcaaagag ggttaaactc attgagatac agtgaacagg
    14521 caactttgag ttcaagaaaa catagtgaag atatgagaga taataatttt tttgaccatg
    14581 taaataagaa gaatgaaact ccatttgaca gaatgaaaag agaaggtata gtatatactt
    14641 cagctggaga aaacatagca gcaggacaga ttaatgcaat atatgcgcat gaagcttgga
    14701 tgaactctga aggacataga aaaaatattt tggggaacta taataatatt ggagttggag
    14761 taatatttgg aggaagctat aaaacatatt acactcaaaa tttttataaa taactaaaat
    14821 atttgaaagg aagttaaaaa atgacatcat ggaaaaaaaa gacagtatat aagtgcttaa
    14881 tagcagtagc cttgttttgt ggaatagtgt taatatctaa ttttagtaaa gtttctgctt
    14941 tgatgatgga tactaatgga aatgttttga ttaaacatgg ttcaagggaa aaaaagctaa
    15001 tagcaattac ctttgatgat ggtcctcatc ctaaagaaac tagtcaagtt ttagatgtat
    15061 taaagaaata caatgtaaaa gctacttttt ttatagctgg aaaacatgca aaatggtata
    15121 aagaaccatt agtaagagca agtaaagaag gtcacgagat aggaaatcat actttcaatc
    15181 atcctgatat aagtaattta agttctagtc agatagaaga ggagattgtt aagtgtgaag
    15241 acattttgaa ggaagtaact gggaaaaaac ctacattatt tagaccacca ttcggaagtt
    15301 atagagaaaa agacttaata gaaattgcaa aaaagcatga ctataaagtt gttttatgga
    15361 caggtgtaga tgtgaaagat tggaaaaatc caggagctaa tagcattgca gataaaataa
    15421 ttaataaagt acaaaatgga gatataatac ttttgcatga ttatgcaact aatgatacag
    15481 ttgaagcttt agatatgttt attccaaaaa tgattgaaaa aggttttaaa tttgtaacag
    15541 tttctgagtt gataaaataa tttttagggg ggagatttac agtatgattc ttatgataga
    15601 caattatgat tcttttgtat acaacctagt ccaatatata gaagaattag gggaagcagt
    15661 tgtagtaaaa agaaataatg aaatcaaaat aagtgacatt gaagaactaa atccagaggt
    15721 aattgtgtta tctccaggac cgtgttctcc aaaagaagct ggtatttgca tagatattgt
    15781 tgagcatttt aaggggaaaa aacctatact aggaatttgt ttaggtcacc aaactattgg
    15841 acatgttttt ggaggagata ttataaaagc acaacagcct gtgcatggaa aagtatatag
    15901 tatcaaccat actaataaag gagtttttag gggacttaaa aatcctttaa atgtcactag
    15961 gtatcattca ctaatagttg actccaatac agttccaaaa gaattagaaa ttacagcaat
    16021 tactgataaa ggggaaataa tgggaattag gcataagaaa tatttaatag aaggagtaca
    16081 gtttcatcca gaagctattt tgtcagagta tggtcatgaa atgcttaaaa attttataac
    16141 agaagctaga gaaagggtac atatgtaata tgataagaga gataaatact aaattaaatt
    16201 cttttgagat atttactatt tttagaaatg aacatgacag ttttatatta gatagtgcta
    16261 tggataaaga aaaattggga agatattctt ttataagtag ccaaccattt aaggtattaa
    16321 agtataaaga tactgatgaa aatcctttag aagttttaaa agaagaacta cataagtata
    16381 gggttgtaaa tgatactaat cttccatttg taggaggtgc tgtgggatat ttatcttatg
    16441 atttaggtaa ttacatagaa aatttaccta gaactgctgt agatgatatt gagatgcctg
    16501 atatgtattt tggattttat aatcatgtaa tagttataga ccatcttgtg caaaaaactt
    16561 atatagctac tccaaacata gatatcgaat tagaagaaaa gataatagat gatatagaac
    16621 aaagaatatt aaaagaagag aaaaaaggta tagatagcat atgttatgaa gaaaaagaag
    16681 taacacctat aagacttaaa tctaatttta caaaggaaga atttaaaaat gcagttcaaa
    16741 gtgttagaga gtacataaga caaggagata tatatcaagc taatttaaca caaaggttca
    16801 gtggagaaac agaacttaca agctttgaat tgtataggga cttaagaaga tttagcccag
    16861 caccatttgg ggcattctta aactttgaag atgcacatat attatcaaat tctccagaaa
    16921 gatttataag atgtgttaat aagagaatag aaactagacc aataaaaggt actcgtccaa
    16981 gagggaaaga taaagaagaa gatttaagac ttcaacaaga acttagaaat agtgaaaaag
    17041 atagagctga actacttatg atagtagatt tagaaagaaa tgatattggg agaatatcta
    17101 aaactggaag tgttaaagtt ccagagctat ttgtaattga accatatgca aatgtaaatc
    17161 acttagtttc cacagttgta ggtgagttaa aagatgataa agatgctact gatgtaataa
    17221 aagcaacttt tccagggggg tctataacag gagcacctaa gattagagca atggaaatta
    17281 tagacgaatt agagccaacg caaagaaatg tatatactgg ttcaataggt tatataggtt
    17341 ttaatggtga tatggatttt aatatagcaa ttagaacaat aatcaaaaat gacaaaaaag
    17401 tctactttca agttggagga ggaatgactt gggattctga cccagatgaa gaatatcaag
    17461 aaacacttga taaagctaaa tccataatga aggctttgag gggatattat gaagaataat
    17521 gtaggttttg atagtagttt aagtaaattt ggaattggtt tgtttgaaac tattagagtt
    17581 aaaaatggaa tagcagtaga tttagatatc catatagaaa gaatgctaag ctcaataaat
    17641 tgtttggatt tagatataaa ctataaaaaa gatttcttga taaatgaaat tgttacatat
    17701 ataaaaaaag aaaatgtcat taataaagca cttagaatta ctgtttttga tgaaggttat
    17761 aatatatcta ttagggatat tccatataat caagagacgt atgagaaggg gtttaaatta
    17821 gctatatctc caatagttag ggggaatagt ttaattcata gacataagac tactaattat
    17881 tttgaaaaca tatataccaa aaatatcgca aataagactg gttataatga tggtatattt
    17941 ttaaattcag aaggtgtaat attagaatgt tctatgagca atattttctt tataaaagga
    18001 gaaagagtgt acactcctag tgatagatta ccgatattaa atggaataat aaaaaaaagg
    18061 attatagaga tttgtgacga attacatata gagttgatag aaaatgaaat taatatatca
    18121 gaaattagta gttttgattt tgtttttgtc acaaatagtc ttatgggcgc tataaaggtt
    18181 acagaaattg acaaaataaa atttaataaa gaaaatgttg tttttgataa aatagtgaag
    18241 ttattagaat aaattaaaat attaacaatt tgttggagac aaaagatgat aggttgtatt
    18301 tatgaagtat acaatgaaga gatgactaaa ataatagaaa accaaaacac tttggctgta
    18361 tatttagtgg gttctagtaa agatgtagat tttactcttt atgatgtagt gataaacgat
    18421 attgatgtgt tcgtttttgt aaaagaaggg gaaaaacaag agagaatact gtttaaaaaa
    18481 aagggaatag aatttgatgt aaattacttt tcaaaagatg gtgtaaaaaa attattatca
    18541 aatagggaat atttctttgt gaaagaaatg aaagatgcta aagtactgtt tgatagggag
    18601 aatatatcac atattataaa agatataagt agagatattt acttagaagg acctagtaaa
    18661 atgtcattag aggaaaagtc ttttataaag caagatattg gagcaaaaat attgaattta
    18721 aaaaataaag aaaaatttga tgtttttgaa tatcattttt tgacgaattt atatttaaaa
    18781 gatataataa ttgggtactt taatataaat gataaatggg taccaaaaga caaaaaattg
    18841 ctaaaagttt taaaaaaaga aaataatgag ctttttgaac tagtgtcaaa agtaagtgaa
    18901 aattatgact atcaaagact tttagatgtt tataattata tttttaaaga aattgagaca
    18961 aaagaggtta taaaactaat cttctagtca caaatcaatg gggggagttt aaatgaataa
    19021 agttgataaa gaaaagatac aacatgcagt aagagaaata ctagaggcaa ttggggaaga
    19081 cccagataga gaaggtctaa tcgaaactcc aaatagagtt gctaggatgt atgaagagat
    19141 attctctggt cttagtgaag aaccaagaga ccatttaaaa gttctttttg cagatgaaaa
    19201 acatgaagag ttagtattgg taaaagatat tccattttat tcatgttgtg agcatcatct
    19261 agttcctttc tttggaaaag ctcatattgc ttatttacca aaaggaggaa gacttacagg
    19321 gctttctaaa cttgctagag taatagatac attggcaaaa agaccacaat tacaagaaag
    19381 aatcactaaa aatgctgcag atataataat ggaagaatta caaccttatg gtgtcttagt
    19441 agtagtagaa gctgaacata tgtgcatgac aatgagaggc gtaaaaaaac caggttcaaa
    19501 aactgttaca tcagcagtga gaggaatatt tgaaaaggac attgcgtcta gagccgaggc
    19561 tatgagtttg attactatga agtagtaatt tattatagat ataatcattt attgagataa
    19621 aatttaattt aagggagtgt cattaattgt gtttgattat ggtaaaagaa cttatataat
    19681 gggaatatta aatgtaactc cagatagttt ttctgatgga ggagatttta ataacttgga
    19741 catagcaata caacatgcaa aagatatggt tgaccaaggt gcagatataa tagacctagg
    19801 aggagagtct acacgcccag gtcatagcta tgtagactca gacgaagagc taagaagagt
    19861 aatccctgta ataaaaaaac ttaaacagga attggatata ccaatatcaa tagacactta
    19921 taaggcagat gttgcagaag aagcattaaa attaggtgtc actatggtaa atgatgtttg
    19981 gggtcttaga aaagataaaa atatggcttc tgtaatagga aaatatgatg cagaagtgtg
    20041 tataatgcat aatcaagatg ggacaaacta tgacaaagat ataatggagt caataaaaga
    20101 cttttttaag gtaagtatag aaatggcaat gagttgtggt gtaaaaaaag aaaaaatagt
    20161 acttgaccca ggtgtaggat ttggcaagga ttttgaacaa aatattgaag tattgagaag
    20221 attaaatgaa ttaaaagatt tagggtatcc tattttgctt gggacatcca gaaaatcagt
    20281 aataggaaaa gtacttccag ttgagcctaa aaaaagatta gaaggtacaa tagctactac
    20341 tgttcttggt ataagagatg gcgtagatat agttagagta catgatgttt atgaaaattt
    20401 aatggcagct agaatgactg atgcaatata tagaaagtag gtataatata atggataaaa
    20461 tattacttag taatctagga ttctatggat atcatggtgt tcttaaagaa gaaaattttc
    20521 taggtcagaa attctttgtc gacatggaac tttatattga ttcaagagaa gcaggtctta
    20581 gtgacgatat aaataaatct gtaagctatg ccgaggttta caatgttgtt aaagatatta
    20641 ctgaaaataa acaatttaat cttttggagg ctttagcgga aaatattgct gaagaagtct
    20701 tgaataaatt tatacttata aatggagtta tggtcagagt tagaaagcct gaggctcctg
    20761 taaatggtat ttatgactat tttggtgttg agataaggag aacaagagat gaataaggct
    20821 tatttgggaa taggtactaa catgggtgat agatttgata atttatcaag agcatgtgaa
    20881 cttttgaaaa atagtgattc tatatataaa gtaaaagaat caagcttata cgaaacaaaa
    20941 ccatggggat atacagaaca agcagatttt ctaaatatgt gtgtagaaat agaaacagag
    21001 tttgaacctt atgagttgtt agaatattgt caagaaatag agagagaact acacagagag
    21061 agaatagttc attggggacc aagaactata gatgtagacg tactattttt taatgatgta
    21121 gtttccactg atgaaagact aacaatacct catccaagga ttcaagatag agctttcgtt
    21181 ttgataccac ttatggattt aaatgaagaa cttataataa atgaaaaaac aataaaagaa
    21241 catttaaacc tcctatctgc tgaagaaaga gaagaagtaa aggagcttgt aggttatgaa
    21301 agaaaaccta tttaataata attcaaagat agagataaat acaaataaca aaaagataac
    21361 tgtaaaaaaa gataaactta taatagctgg accatgtgca atagagagtt atgagcaact
    21421 tttggagact gctaaatttg taaaaagtca gggagcaaat attttaagag gtggagcata
    21481 caagccaaga acatctccaa attcatttca aggattaaaa aaagaaggtc ttgaaatatt
    21541 aaaagcggtt aaagacgaag ttggtatggc tgttattaca gaacttatgg atgtaagaga
    21601 tatggacgaa ctgtatagta taagtgatat aattcaaatt gggtcaagaa atatgcaaaa
    21661 ctttactctt ttaagtgaag tgggaaaaca aaataaacct gttatgttaa aaagaggaat
    21721 agcttccaca attactgaat ggataggtgc ttctgaatat atagcaatag aaggaaatag
    21781 taatattata atgtgtgaga gaggtataag aacgtataat gattatacta gaaatacatt
    21841 agatttagct gcagtaccca ttattcaaaa ggaaacaggt cttcctgttg tggtagaccc
    21901 aagccatgcc actggagtta gatatttggt aaaacctatg tcactggcat cttttgcatg
    21961 tggagcagat ggaataatgg tagaagtaca tcctgaccca gaaaatgctt tgtcagatgg
    22021 tgctcaatct ctttgcttta atgaatttga agatttaatg aaatcaatta ataattatta
    22081 aaagaggcaa gagcctcttt tttattcgta atcgttgcta aggtaaattt ataagttata
    22141 atttgatagt tagattattt aatataaata aagatttaat attgatagaa ttaatataaa
    22201 aaataaaaat tttttgatta ataagaagga tatcaataaa aaaagtcgaa ttgtgtatat
    22261 tgagtgattg acaaatttag aatatagtgt agaatagaaa tgttaacaca aaaaattaca
    22321 ccagaaggtg ataatatgaa tgatataaaa gacattattg aagaaataaa agctagatgc
    22381 gatatagcaa gtataatatc tgaatatatg aatataaaac aatctggagc taattacaaa
    22441 ggattatgtc catttcatgg cgaaaagaca ccttcttttt atataaatac gtcaaaacag
    22501 atttataagt gttttggttg tggtgaaggt ggagacgtaa taaattttgt catgaaaatg
    22561 gaaaatttgg attttatgga tgctgtaaaa attttagcaa ataaatgcgg tatagaaatt
    22621 aacactaaca tgaatgaaga aactaggatt aaaatagaaa aatctaagaa atttcaagat
    22681 attcatacgg aagcagctag attttatctt tcaaacttat tgggaagcaa aaatcttggg
    22741 tatgaatatt taagaataag aggactagat gataaaatta ttaagaaatt tggtttagga
    22801 ttttctttgg attcatggaa ttcacttatg aatactctaa tcagtaaagg atataaaaaa
    22861 caagacttat tggagtgcgg tctaattgca aaaaatagag atggaactaa ttgctatgat
    22921 aaatttagaa atagagttat gtttcctata ttcgattata gaggaaatat aataggattt
    22981 gggggaagag tattagacga ttctttgcca aaatacttaa attctccaga cacgttaatt
    23041 tttaataaaa aacagaactt atacggatta aattttgcta gaaaaaattt agaaagtaaa
    23101 actatagtct tagttgaagg atatatggat ttaatttcgc tttatcagta tggtataaaa
    23161 aatgtagtag caacccttgg aacagccttg actgaacaac aaggcatttt aataaagaga
    23221 tatgcggaca ctgctattat atcttatgat tctgatgaag caggaataaa agcgacttta
    23281 agagctatag atatacttac taaattaggt atcaatgtaa aagtgttaga cttaaaagat
    23341 gctaaagacc cagatgaatt tgtaagaaaa tacggactta gtgattataa aaaagctatg
    23401 gatgtttcta ctcactacat aaaatataaa atagatcatc ttaaaaaaga atttaacatt
    23461 caaaaagatg aagaacgagt gaagttcgca aaagaagctt ctaaaattat aaaacaattg
    23521 acaagtcctg ttgaaattga tttttataca aagtatttaa gcaatcaaat agatattaat
    23581 gtcgagtcta taaagagaga agtttatggt aaaaattaca ataagccata taataacaaa
    23641 aatcaaaaga aaatagaaga aaaagtaatt gaaaaagtcg aagtcagaca agacggaaaa
    23701 caattagttg aagaaactct aataaaaata atgttagaag acaaaaaaat tagagaaata
    23761 gcgttactta aagtagaaga aagtgatttt ttattgaaag aaagtaaaga aattttaaat
    23821 tacatgatta aaaatcaaga attggacaaa ataactattg acaaattgaa aagtttaaac
    23881 atatccgaag aatacttaaa agaattaaat tcaatttctt tgaatagtat aaacttagag
    23941 aacacaaaag aaatagaagg aataataaca aatatcagaa aaaactcatt agaagagcaa
    24001 attaatagct tgttgagaga acaacaagaa ttagaaaata ataatgatat gaaagaggta
    24061 gatggtagag ttatggaaat tgctttaaaa atagttgaga taaataaaat tttaaagagc
    24121 ttgtagagaa aggaggtttg agtgtggaaa ataaatcgaa taaaaaagag ttaaaaaagg
    24181 ttactgctaa gacattaata gaaaaaggaa aaaagcaagg ttctctgaca cttgcagaga
    24241 taatggaagc tttttcggag actgaacttg ataaggatca agtagaaaat ctttatgaga
    24301 ctttaggaaa tttgggaata gaaataacag aaacaaaaaa ctataaagct gatatagatt
    24361 tttcggttgc tgatgacgat ttaagtatag gccacttaga tgaagatgca gaggcaattt
    24421 cacatgatga ctcttctgca atagaaatag aaactgtgga tttatcttta ccaaaaggga
    24481 taagtataga tgaccctgta agaatgtact taaaagaaat aggaaaaatt cctctactta
    24541 aaccacatga agaagtagaa tttgctagaa ggatgcacga aggtgatgag atagcaaaac
    24601 aaaggttagt tgaagcaaac ttaagactag ttgtaagtat agcaaaaaga tatgtaggaa
    24661 gaggtatgct tttcttggat ttaatacaag agggaaattt aggtcttata aaagcagtcg
    24721 aaaaatttga ctatacaaaa ggatataagt ttagtactta tgcaacatgg tggataagac
    24781 aagctataac acgtgctatt gcagaccaag ctagaactat aagaatacca gttcatatgg
    24841 tagagactat aaataagcta ataagagtat caagacaact acttcaagaa cttggaagag
    24901 atccaaaacc agaagaaatt gcaaaagaaa tggaaatgac agaagataaa gtaagagaaa
    24961 taatgaaaat agctcaagac cctgtgtctt tagaaacacc aataggagaa gaagaagata
    25021 gccatttagg tgactttatt ccagatgatg atgctccagc cccagcagag gcagcagcat
    25081 attctttatt aaaagaacaa atagaagatg tacttggttc attaaatgat agagaacaaa
    25141 aagtattaaa gcttagattt ggtcttgagg atggtagagc cagaactctt gaggaagttg
    25201 gaaaagagtt tgatgtaact agagagagaa taagacagat agaagcaaaa gcactaagaa
    25261 aactaagaca tccaagtaga tcaaaaaaac ttagagatta tttagactaa aaagatacat
    25321 cattgatgtt tttgtgataa atgccatgag ataagtgata tctcatggct attttgtagt
    25381 aaagatttaa ttttattttt gtagttattt cagtctaata tctataactt ggattaaatc
    25441 ctataaataa agggaattga aaggagaatt atatttgaaa ttaacagata gattattgaa
    25501 aatagcatca ttagtgtcag atggtaaaaa aatagctgat atagggacgg accacggata
    25561 cataccagta tatttgttaa aagagggaaa agtaccattt gcagtgctag cggatgttaa
    25621 taaaggacct cttgacaatg cacataaaga agtcatacag aacaatcttt tagataaagt
    25681 tgatttacga ttgggttctg gtatagagat acttgaaata ggggaagtag aagaagtgat
    25741 aattgctggt atgggtggaa tcttgataag tgagcttctc gaggctaaaa aagaagtagc
    25801 acataatgta gaaaaattaa tattacagcc aatgcaagca caagaagaac ttagatatta
    25861 ccttttaaac aacggatatg aaattttaga agaagtttta gtgagagaag attttagaat
    25921 atatgagata attgttgcca aatatacagg taaaaatact ataatagaag atgagatata
    25981 ttatgaggtt ggaataaagc ttttagaaaa caaagattct ctttttaatg attttataga
    26041 aaaaaagata aagacatata gttctatagt taataaatta gaagggaaaa atggggaagc
    26101 tatagataag aagagaaagg aaagcgaagt tgcaataaaa aaacttgaaa atttaataaa
    26161 ataaatagga ggtatatatg ctattaaaga gtctaactag aaaaattgaa aaaaagtatc
    26221 ctctaaactt agcagaggat tgggataatg taggtcttat agttggagat tttgatatgg
    26281 atgtaaaaaa ggtattggta tctttagaag ctaatgaaga tgttattgat gaagctatat
    26341 ccaaaaatat agatttaatt gtgacacatc atccttttat atttgggaaa attaataaaa
    26401 ttaatagtgg agatttaaaa ggcagactta tccaaaaact tattaaaaat gatatatcac
    26461 tttattctat gcatacgaat tttgatatag catttgatgg tctaaatgac tattttatgg
    26521 aaattatgga atttggtaat tcaaaggttt tagatataac taaaagcgaa aatttgtata
    26581 aattagcagt atacgttcca cataactatt cagatgaact tagaaaggtt ttaagtaatt
    26641 caggagcagg tcatataggg aattatagtg attgtacgtt ttcaatagaa ggtgaaggac
    26701 aatttaagcc attagaaggc tctaatccgt ttcttggaag tgtaaatgat atagaaactg
    26761 taaatgaagt taaaattgaa actgtagtac cacagaagct tttaggtggg gtaataagtt
    26821 ctatgttaga tgcacatcct tatgaagaag ttgcatatga tttgtacaag ttagaaaata
    26881 aaggtgagat atttggacta ggtagaataa gtaaacttga taaaagtatg acattagaaa
    26941 gtctttcaag gaaaataaaa gagaaattaa atatgaaaca cataagagta gttggaaacc
    27001 ttagtacaga cataacgaaa gtagccgttg taacaggagc tggttcagaa tttgtaaaaa
    27061 aagctaagag acaaggtgca gaagtactaa ttacgggtga tgtaaagtat catgaggcac
    27121 aagatgcact tgatattgga atgtgtatag tggattgtgg tcattttgat acagaagata
    27181 tattcaaaaa tgttatgaag agatttttag atgaatttag tgaaattgaa gtaataaaaa
    27241 gtaatgtata tttgaatcca tttagtacta tttagcagtg tttgataata aaaatactat
    27301 ataaaaaata aatttgagtt taattagggg gataatgatg aaagtagcag taatttttca
    27361 tagtgtttgt gggagtacat atttattagc tagagaatat aaagaagcgc ttgaagaaat
    27421 gaatatcgag gtagatatat ttagagtaag tgacgaagtt gcaaaaacac ttcctcaata
    27481 ttatttgata aattccaaag aatacaaaga cgaatttgaa agtataaatg taattaaatc
    27541 tggaaaagaa atattagatt atgatgctat atttatgggt tcaccaacat attatggaaa
    27601 tgtatctgga ccaatgaaga tgtttatgga tagtttttct gatatttggg taggtactcc
    27661 tttgagtggt aaaatatttg gttgttttgc tacagcaggt tcacaacatg gaggaggaga
    27721 attagctttg caagctatga atatatttgc ccaacatatg ggaatgactc ttttgtcagt
    27781 tccatgttca gtaagaggag gttatccagc gtatggaata cttcatatag caggagataa
    27841 ttctgatata agaccaaatg atgatgccaa gataggtata agagattacc taaaaagact
    27901 taacatataa gaatatcata taaaaatacc taaaagcgac tgtatatact tttaggtatt
    27961 tttacttaat tataaacgtg aagctttacc agaaatatgg tcaatttcta ttttaacaac
    28021 agttgttaag ttcatatcct tctctatgta cttcatgcct tcttcaaaga atcctttaga
    28081 atattttttt attatttcta caagagcatt tttcttttct tcattttcta cagtgcaagc
    28141 ttttccaaaa actatagcac tagaataagt agtactaaat ttatctggaa taacactttc
    28201 attagcaact actaaaaaag aaactttgtt gtttttcgat atattatcta acttatgccc
    28261 atttcttgca caatgaaagt aaatagaatc attaaagtat acataattta cagcaactcc
    28321 ataaggataa ccattttcag atatagtgga aaaagtacca aattcaccat tttttaatac
    28381 ttcaacagta tcttcttttg tcatttctct ttttttcaat ctcatttctt taaacataat
    28441 atcatccttt ctaattttga tgcttaaatt aaattttaga acatttataa agattatgct
    28501 atgtttttta caaattttaa gaaaaaaata tagtttaaga taaaaggtag tgaaagagaa
    28561 gctatttgga ggtttattta tgatattatt gttagagtag tataaacaat actaataaat
    28621 ttaatagctg gtttcttgtt atttaagata gtaagcatgt ctataagaag gggaagttat
    28681 cgagggtaga agttgttatt tataactata ttataaagaa aatattatta tataaaataa
    28741 taaatagtaa agaggtatca agttgaatat aatacttaat acctcttcaa aattaagtta
    28801 taaaagtgtt gtgggaattg tcctatacat ggtaaggaga taataaagaa tgtatcttta
    28861 aagtctcaac taaacagcaa aatttatcca acaaacatac aataaatgct tctttgtatc
    28921 taggtggctt aacagtaagt ggccacatgt gttttaaaat tatgtccgtt tctttttcat
    28981 ttatttgaaa aaataaagtt gcatttttta atgcttctct agggtgagta aatccatgta
    29041 atccttttct atcacctttg taatgccaat cataaagaaa aaagtcgtgt agtaaagctc
    29101 ctctaataac actttgaata tcaacactta agtgcaattt tttacataat agataactat
    29161 aatatgctac tgacaaacta tgttcaagac atgaaacatt gccatgatga ggaaatgttc
    29221 tcataagttg aactttttca gaagaaagta tctcagaagc acattcatta aaatatttga
    29281 tttcagcttt tgacaacatt atgaaaatct ccattcttag taatatataa atactatact
    29341 tcaacgataa tatgaaatat ttcttatcct acaaaatata atacccaata atacaagtaa
    29401 gatacctttt atggtatttt aaagtaagag agattttatt aggctaaaca atgaaaaaat
    29461 taaaagtaaa gctatagcaa tatatagtat ttttccaaga ggattgccaa aatttatagt
    29521 ccatccaata ccaaaccttt tattaaccat taatgatggg tcatttggat tattatacat
    29581 gatgcctgct atccaatact tctcatcttc ttctggagaa taagatgagt tgaattttaa
    29641 atttggggaa ttaatatatg ttgctattaa ataaattata actaaaagcg ttgtaatatt
    29701 catagcagtt gatagttttg tttttattga taaaagagta gtaaaaaact gtgttgtcat
    29761 tataatcatc aatattaaaa acaaataacc aattttattt aaatatttaa tgttttcaac
    29821 tctactttct tcaattctat ttgtatctat cttaatcctt gactttatgg atccaatgga
    29881 agttatatat aataaaacca ttaaacaaaa gtcagtaccg attaatttaa atacattaag
    29941 aaatgattta tctataaaaa catcaggaga cccatttatg ttccaatgag tggcaattga
    30001 gtctggcaat tgattataat taaatgctat aaaaatactc attcccaaag taaatagtat
    30061 cggtattaaa tagattattt taaatttttt tattatttta tttttcttat ttataaaatc
    30121 catatctact attaattttg aatctatatc tatatgacct aatttagaat aaatttctga
    30181 tttaagcttc ttagcttttt tatgtgtatg aatatatagt atactttcat ataataaaaa
    30241 acctataata ccaataaaat aggaaagttc caatttatta aatgtaaaga ccagaataaa
    30301 aactaatata aagtctataa taaaacctaa agataatagt tttttaaatt ctttatctaa
    30361 ctttataaag taattataat ttttatgctc ttggtctata gaaactccat agatgtgttt
    30421 tttacctaca aaatagggca taaaataaaa tgtagcatac atcaaaatta gaactggaaa
    30481 tattgtaaat agacattcaa tcttactcat aatatttcac ctcatacttg tcaaataaac
    30541 ttgaacttag tgacaaaaat tcttctttac taatacctga taaataagat tttgccacca
    30601 ataattccaa gtcaagttta tttttttgac gagttgtatt atctattttc attggtagtt
    30661 gagctacaat agcacctttt cttctatcaa tatttaagaa tccctcttct tttaattcat
    30721 tgtaggattt gttcactgta tgtaaattta caccaatatt ttcagccata cttcttacag
    30781 atggaagtga ttcatttatt ttcaattctc ctgaagctat agccttagtt atttcttctt
    30841 taatttgtac ataaatagat ttatcactat taaaatctaa atttaaaacc ataaaaaacc
    30901 tccattatgc tttataaatg aaaacgattg ttatatacat agtataacat aaaaaataat
    30961 aacaaacaca aaatataagt ttatattttg taaaaattgt aatttaaaaa ataacataat
    31021 ttttattaaa ataatacaga tactatttat agatagaaat aaaaattaga aaggagaaaa
    31081 aatatgttaa catatttaat gaaaagacaa atgcataaaa aagatgatgg aatgagtaaa
    31141 ccaatgatga ttacaggagc tgtaattaca ggtgtaggag catatgctgt atataaaatg
    31201 gtaaaaagcc ataaatctaa ttctcaaatg gtcaatacaa attattatgg aaatagcgat
    31261 tatgatgatt ataaatatga cgaatttgat tatgactgtg attgtagaga cacaaaacaa
    31321 gattatgaat atgaagaatt aaaaaaaaaa gtaaaagaat ttaattcaag aagaataaat
    31381 tgtgaaaatt gtccacatgt ttctcaagaa gaaatgatgc aatatgtaaa tagtgttaaa
    31441 gatgtaaagg aagagattga tttacatgaa gatgctaaaa aagataatat ttacaaagaa
    31501 gatgaataca aaaaatatga agaagaataa gtaatatttt gtataactga acaaatagta
    31561 atgtcaaatt atttaatatc tagttttaat atgtaagttg taacttaact tgaaagaatc
    31621 agtatcattc tttagatagt taagtaacaa cttacatttt atttttataa attttaatag
    31681 ttctttgtga ctattttgta attttagaaa tattttagta tccagggtaa ttgtgtataa
    31741 taaaacttgt atagatagat agtatgaaat taagcagata gtttaaaatt aaaatgaaaa
    31801 gaaaggaaat agttatgtta aagttgttga tagttgaaga tgatagtact atatcttttg
    31861 gaataaagta tgctttagaa caagaaggat ttagtataga tatatcaaag gatttatcta
    31921 gtggaaaaga aatgatttct tctaatgaat atagcatgat actgttggat gttacattgc
    31981 cagatggaac tggttatgag ctttgtcaat atataagagg attctctcag gttcctataa
    32041 tattcttgac tgcttgtgat gaagaagtaa atattgtaat gggtctcgat ataggtggag
    32101 atgattatat aacaaaacct tttagaatta gagaattaat atccagaata aaagctgttt
    32161 taagaagaaa aggtaatact tcagaagaaa ataagaaaat acttaaattt ggagatttaa
    32221 gtatatatac attagaagct agagtatata aaaatgataa agaaatattt ctgacatcag
    32281 ttgaatataa acttctttta attcttatac agaataaaaa tactgtttta agtagaactc
    32341 aaatattgga aaaactttgg gatgtaactt atgattttgt aaacgacaat actctaactg
    32401 tttatataaa aaggcttaga gaaaaaatag gtgatgattt atgtgaacca atctacatag
    32461 aaactgtaag ggggattggt tataaatgga taggaagtga aaatagtgtt tctatataat
    32521 ccagaagtga agaagttttt aagtaagtat gttactttga tgtttattgt tatcataata
    32581 tctattggat ttagcataat caacgtgtcc ttaactaaag agatggttgt aagaaataat
    32641 caggctataa taggaacttt atcaagcaag tatccaaact tggaaagtca gatagtagac
    32701 ataataactc aagggaagtc tatggagaac atagattatg gtcagaaaat attaattaag
    32761 tataattatg ataaatctat taggataaac tctgagccta ttatttctaa attagtttta
    32821 gagactatca aaataaatat aatattagta tgtataatat ttattttgat atttgtgttg
    32881 gttgttagat attttaagtc aatttacaat gatttatcag atatgactaa gtatgtttac
    32941 tatagttcag agggtaagcc atttgatatg aaaaacaaga atcaagaagg gcagataggt
    33001 cttctaaaaa ctgaactctt aaagatgaca acaattctta atgaaaaggt tgaactttta
    33061 aaaagagaaa agatattttt aaacaataca atttccgata tatcacatca attaaaaact
    33121 cctatgactt ctttaataat gttgaatgat ttattatata atgatgtacc atacgaagta
    33181 aaaatcgatt ttttaaataa gataaaaaat caattaaata gaatggattg gttgattaaa
    33241 agcatgctta aattatcaaa ggtagaagca aaagtgataa attttaaaaa agataaggta
    33301 aaatttagtg aactcataca tagagcaatg ctatctatga aaatacctat ggagattaaa
    33361 aatcaaaaac tgactataga gggaaatgat aatgtatctt atattggtga tattgattgg
    33421 tccgtggaag cattagtgaa tataatcaaa aattgtgtag aacatactcc tgaatttgga
    33481 aatataatta taacctataa agaaaatcca ttattttctg aactaataat aaaagatgag
    33541 ggtgaaggta tagataaaaa agatatacca catgtattta aacgattcta tagaggaaga
    33601 agtagttcaa aagaagatag tgtaggaata ggtcttgcaa tgtcaaaatc tataatagaa
    33661 agccaaaatg gcgatatata tgtaaacagc gaaaaaggtc agggtacaga atttcatata
    33721 atatttcata aaatgtatga tagtgactaa tctgtaatat ttaattcact ttatagtaat
    33781 agccaaaacc taatatatga agtatagaat ataaatattg gaggtagtta tggaaatttt
    33841 aagagtagaa aatctaacta aaagttatgg taaaaatgaa acaaaagttg atgctataaa
    33901 aaatgtaagt ttatcagttg aaaaaggaac gtttatagca ataacaggtc caagtggaag
    33961 tggtaaaagt accttattac atttattagg aggagttgac agaccaacta gtggtaaggt
    34021 ttatataaat gatgttgata tatataattt aaaaactaag gatttggcga tatttagaag
    34081 aagaaatata ggtcttatat atcaatttta caacttaatt ccagtcttaa atgtgaagga
    34141 aaacatattg cttccagcag agcttgacaa tagagatatt gatagagaat attttgatga
    34201 tttaatgaaa acattaggtc taattgatag agaaaagcac cttccaaacc aattatcagg
    34261 aggtcaacaa cagagaacct ctataggacg tgcattaatt aatagacctt ctataatatt
    34321 agcagatgag ccaacaggta atttagatag taaaaattca aaggaaatat tagaattgtt
    34381 aaaattgtca gtaaaaaaat acaaccagac actaataatg ataactcatg acaaaaatat
    34441 ggcacttcaa gctgatagaa ttataagcat agaagatgga atcataaaaa gtgatgaggt
    34501 gatgtagatg aatttatata cattactaac cattagatac ttaaaacaaa ataaaagaag
    34561 aaccattgta accataatcg gtataatact ttcaacagct ttaatttgtg gtataggaaa
    34621 tatatttgaa agttttatgg attatcaaat gagagaaact ataaagaatg atggaagttt
    34681 ccatgttaca ttttatgatg taaatagaaa aaatgtggaa tatgtaacga aatcagctga
    34741 aatagaaaaa catgcattta ccaaacaact tggatattct aaattagaaa atagtgaaaa
    34801 tgctatatta agtataaagc aatatgataa aaatgcaata aatggatata aagtttctat
    34861 aaaagaaggt agatttccag ctaaggaagg agaaattgtt ctaagtgaaa gtattattaa
    34921 tcttatagat gataagttaa aaataggaga taagataact ttaaaagtag gggatatgtt
    34981 tgactcaagc aagaaaaaga ttgatagtat gacatttcat gaaggtgatt atatagcaaa
    35041 tgaaaaagat agaactttta aagttgttgg tataattgaa aaacctgggt ttgaacgtta
    35101 taatggaatt gcaacagcta tagcctactt taatcctatg aataattaca atgatacaat
    35161 taatgtatca gtagcagtaa gaaatcctaa agatgtgtat aagataagta ataaaataag
    35221 taaaaatata tattcaaata aagataaaga agcagtttct gatatgataa aatacaatga
    35281 acatttattg aggttacaag gtgctagtaa gtattcaaat ataaataact ctataaagtc
    35341 tataattata gcagtaacta ttttagtaat catatgtaca attgctacag tgtacaattc
    35401 ctttagtatt tctataaatg aacgaaaaaa acagtttggg atattaaatt ctataggtgc
    35461 tacatctagt caaattaaaa gattagtttt tatagaaggt attataatta gtttaattgg
    35521 tataccaata ggactaatat ctggaacagt agctatagac ctattgttta aaattataaa
    35581 taagtatttt actgaatcgg ttgttactaa gatgagtttg cagatagtgt ataatccaat
    35641 aataactatt gttagtataa taatagtttt gcttacaatc tttatatcaa ttctactacc
    35701 tgcaatatcg gcttctaata tttctcacct taatgtgatt aaaaatactg gagagtataa
    35761 agtgggcaaa atcaaaagct caagacttat taaaatgatt tttaaaactg aaggagtact
    35821 tgcatataaa aatattagga gaaatagaaa aaaatttata ataactcttt tttctttaat
    35881 ggtaagtata ataatattta tatcttttag tggctttaca ttacttttac taagaggtga
    35941 agaaattaga aattctcaaa gaaaatatga tttgtattta actgcaaaga acacagctag
    36001 gtctgtagag gatactataa gtgaactaga agatattgat gggataaaaa actttgaatt
    36061 ggcaacagga caatatgtgt ctataagagt aagtgaaaat aaaataaata aatccaagga
    36121 agatttaatc aggaaatatt atcaaaaata taagattgga gatagttatg aatatgattt
    36181 cagtaataat gaattaattt ttccaggaga ttttgcagta aaaaacaaaa taaataactt
    36241 agtacagggc tcttttaata aagagagagc aattgaagaa aatggtgtta tattagttag
    36301 aaaaagtgca tttgaagaaa atgggaagaa aggtgtagta gaacttacca actataaagt
    36361 aggagataca gtaaattgtg aatatcttga tgaaaatgcc ttaagtaaaa aagtaaaggt
    36421 caagattctt gctataactg acgaagaacg tctaggtctt ggttatcaaa atatggggtt
    36481 acaatttata acttatgatg aagttgctaa aaatttaaat ttaaaattaa gtaaaagcct
    36541 tatatttatt gattcaggag gaagcattaa gactaagaag gaaatagaag ctttggcaaa
    36601 taaaaataat tttaactttt atgatgaaag tgcaagcaat gaaagtgaaa aacaagattt
    36661 aaaggttatt aaaatatttg tatatggttt tatagtagtg atatctttag tgagtgttac
    36721 aaatattcta aatacagtaa gtacaagtat aaatctaaga aaaagagaac ttgcagtaat
    36781 acaatctata ggggttactc ctaaaggatt taggaaaatg atatatttag aaagttttat
    36841 atatggtata ctgtcattgt tgtttggaat accaattagt attggtataa ttctaattat
    36901 gaataaactt atttcaggtg taattgaatt ttctccgatt ataccgtgga cagccatagt
    36961 tatctgtata gtaagtgttt ttataataac ttttatagca gggtatatac caatgagtaa
    37021 attaaataaa gaaaatataa tagataatat aagaagagaa agtatataga tataaaaata
    37081 attcttaact atataaaata ttattatatc acttaaatga ttttttattt atataagaaa
    37141 tctaataata aattactaga ggtatttaac tatttagaaa gaattggtat tatataaagt
    37201 aagagaatat ataataagaa agaatatttg attttattgg aaaacaaaag aaaaagaagg
    37261 tgattactat ttctcatata actgcgaaga atatgtataa aagtttagag gaaagaataa
    37321 acaagtttcc acaaggtgct ccaccatctg atacattata caaaatacta aatgtactat
    37381 atacagaaca agaagcgaag ttagttgctc agcttccaat aaagcctttc agagtaaaaa
    37441 cagcagctaa aatttggagt gtaagtgaaa gtgaagcata tagagtattg gataaacttg
    37501 ctagtaaggc tctgatacta gatatagaag ataataaagg gaagaaatat ataatgcctc
    37561 ctccaatggc tggttttttt gagtttgcca tgatgagaac gagacacgat atagaccaaa
    37621 aacttttggc agagctttac tatcaatata tgaatgtaga agaagatttt atcaaagatt
    37681 tattttattc aacagaaacg aagcttggaa gagtatacgt tcaagaggaa gttttaacta
    37741 atgataatga ggttagtatt ttagattatg aaagggctac tcatataatt gatgaatcaa
    37801 ctcatatagg tataagtatg tgttactgta gacatagaat gcaacatgtt ggaaaagctt
    37861 gtgatgctcc tatggatata tgtatgacgt ttgacaatgt agcaaattct ttaataaata
    37921 ataaatttgc aagacgtgtg gataaaatag aatgtaaaga actacttcat caagcatatg
    37981 aacataactt agttcaatgt ggagaaaatg ttaggaaagg ggttacgttt atatgtaatt
    38041 gctgtggatg ttgctgtgaa gcaatggtag cagctaaaag atttggaaat cttcatccag
    38101 tacagacaac aagttttata ccaaatataa accatgaaaa ttgtgtaaag tgtggtaaat
    38161 gtataactgc atgtccaata gatgcgataa gcaaggttaa ggaagatggt aaagaatata
    38221 taaaaattga tgaggataga tgtctaggtt gtggagtttg tgttagaaat tgccataaaa
    38281 atagcattat gttattaaag agagatgaaa aaataataac tccagcaaat tcagtacata
    38341 gagcagttct tatggcaatt gaaaaagggc agttacaaaa tttaattttt gataataatg
    38401 ctctggctag tcatagagct atgggagcta tactgtcagc tatattaaag cttgaaccag
    38461 ctaaaaagat tttagccagt aaacaattaa agtcagtata tttagataaa ttgttaagta
    38521 tgaatgataa atagaaacta acttaaaaaa ggcaaagttt tagacttatc tatatcttaa
    38581 taaacttatc atttaatatt taaatttaat ttttacacat ataaaactta taacttaaat
    38641 aaaaaaaggc tatattcaat taatattact tgaatacagc cttttttagt tatgttaagc
    38701 tatttctttt atttgcttaa atgagttttc atttccattt ccaccaattt gtgttacaga
    38761 tttaaatctc atagttttaa atagttcttt ttgattataa tctagtgagt ttcctactag
    38821 cattacagga gatttagttt ttccagccaa aactccaaca gataatccgt ctattaaatc
    38881 atcttgttta ttcattccat ttttagcaac atataaattg tctatcttag aatccttgta
    38941 aaattctttt attacttttg cattagtttc atttctagtg ctacctgata ttctctgtgg
    39001 attttgaagt ttactttcta tatttttaga aactgtatat tctccaccga ttacataaga
    39061 tttatcaatc tttttgtttt taaacaagtt atttatttca gttatattac tattttcatt
    39121 agtaagtatt ataggcatat cattttgagc tgatacagct ccaatgctta ctgcatcggc
    39181 taatcctttt tcgccattaa ctactgaaat ctttgatata ttgctaatat tgttcaattc
    39241 tttagcaatg ttcatagaag tttgatatct atcacttcct gaaattctag atacagagat
    39301 attgtttgat tttatagtat ctaaagattt ttcatttata gaagcttctc caccaactac
    39361 atatacattt ttaactttta atctctttaa ttcagccaaa gttttttcat ttatttgaga
    39421 gcttccagtc aataatatag gagcgttttt cttgtatgca aatggtgttg cagccaaagc
    39481 atctgcaatt gctgaatcgt ttattaaaac tgcattttca gcattttccc aacctgcttg
    39541 acttatctta atagaagttt catatctatc agttcctgta agtgcacttg catttacttc
    39601 atcttgatat gtaacctcaa atctagcatt tggacttcct aagaaaacaa ttacgcctcc
    39661 ttttggcaat ctaactctat tgttctttgt aactaaagaa tagtttacag gaacaccttt
    39721 atcatcataa acagcaaaag ctgaattttg aggaagatta acttctattt ttttatttgc
    39781 gatatcgtca ccaatcttat accattttgc ataaccattg gattctagtt cacaagtaaa
    39841 agatttttct gctggcaaat tagttataga atcttcacta acatacgtta gtgttccaaa
    39901 agataaatac tctgtaccat tttctttatg aagtttaatg tcggataaat cacgacctat
    39961 tacaccaggt atttctataa aagcatttga gttattctca tccattattt tagtgttaac
    40021 tatataacct ggagtttcat cagaaagact aaaacttgct tttacagagc caaacatata
    40081 gctttgagaa gtatattttt catccactag atagtaacct ttgccacttc tttttttcca
    40141 cacttctttg acactatttg atatattgtt gtcatctact ttttgagcta catagtataa
    40201 acttgctgtc tgacctaatc cagggacatc atcataagag ctcatattta aatatgtgat
    40261 attatttttt tcttttacaa attttaaaca actattacct ttttcagata caaatctatc
    40321 ttgacctatg tatacgtatt tatcttcagg tccattttct atataaggag aagatactgt
    40381 taaagtacca ttatcattaa catctacttt tatcatattt gaagaagcat aaagaccact
    40441 attttctttt aaagagctag gcattttaac ttgttgtggc ttactaaatg ttttatcagg
    40501 ttttatttct ttaattttac ctttttcttt taatgcagat agtaagattt cttgtccaat
    40561 tatttcatta agttgactac ttccaccaga agaaagaact gcaactgcca tattttcatc
    40621 tggaagaact ataagattac tgtggaataa taaagaatct ccaccttttg taagagcttt
    40681 taaattatac tgattaaatg gataagtgtt gacacaatcc caccctaaac catatccaag
    40741 tatagagtct tctccttcag gccatagacc atttaaatat tctttgtttt ccatagcttt
    40801 tactgaagca ggagaaagaa taccatttga atttttcata aatgtttgtg caaatgtaca
    40861 tagattttct gcacttgaat ataaaccacc tgcacctata gcattaaggt tatcttgtgg
    40921 aactgcatct tcccaataag gtacatatgc ttttgctagt tttgaactat caaaactatt
    40981 ttctggagtt tttgtatttt gtaagttaag tggattattt atgtatttat caagaaaatt
    41041 agtaaatgac ataccagata ctctttctac taaaatttca gctaaagtaa atccatcatt
    41101 acaataaaca gaaaaagctc ctggtttagc ttttaatctt tgtttttgta attcttttaa
    41161 gaaattatca tgaccataag aatcattgtc tgctaataaa atagtgtttt taaaactact
    41221 tcccatcaac cctgatgagt gatttaataa cattcttgga gtgatttcct tgtatctatc
    41281 atcagccatt ttaaattcag gtatatactt tacaacagga gtatctaaat ttaattttcc
    41341 atcatcaacc aacttcataa cagctgttgt agtaaacatt ttactgatag atgcgatact
    41401 atacatatta tccttattta agtttttgtt atcctgtttg ctgtaaactc caccattacc
    41461 agaaatctca attttgccat tatcaatcaa agcatattga gcacttacag caccatactt
    41521 tgatagcaaa gtttggattt tctctttagc aagagcttta gtttttgtgt aagattccgc
    41581 gtttttacta taatcatgta attctatatc agaactttga tatttttcgg aattatcttt
    41641 tgtattatca gcaaaagtaa tatttggagc agcagtaaat aacatactca atactaatgt
    41701 actagataat aatttagaga gcctttgctt aaacatatta cattacctct ttcccttttt
    41761 aataatttat aattagcata acattcttaa ttattttaat caacagatta ttatcaataa
    41821 aaaaagcttt tataagtata gctttttata taacagagaa aaatataaaa ataatatttg
    41881 ttgttgtata aagaataaag ggtataggta atatataaat aaaatggagg aattttagac
    41941 atatgtataa gaatataaat aagaagcaac ttaaagaaat gatgaaaaat gaaaaggatg
    42001 ttttattatt agatgtaaga actaaagatg aatttaagga atataaaata gaaaatgcta
    42061 taaatatatc tttacaagag ttaatcaata atatagatga aatttacgat tataaagata
    42121 agaaagtagt agtttattgc agaagtggtc atagaagtgt tactgcatgt aatttgttag
    42181 ctgaagaagg ttttgagcat ttatataatt taaattcagg aataattgat tatatgagtt
    42241 aaataatgta agttatacat taaatactat gtatagctct gcttattaag taggaatata
    42301 tctaaatatt tataagataa atttaggaaa gaacgaattt tttcgttttt ttctatgaca
    42361 gtttttgtag taaatattag tttttaagtt ggaaaaaggt agtagctttt tagctactac
    42421 cttttaatat gaacttagaa tattattaaa aaaatatatt taaagacaga attaattttt
    42481 taatgaccag ttaaattact atcgccgaat ttatcattaa atggttttat aactctattt
    42541 ataggtcctt ttagaagtac atttaaacaa atagacagaa tcataaatag taatagaact
    42601 agtatatctt tagttagatt tggagcatat ataccaccaa ctgcttccct tgtagcacct
    42661 attgcatagg taaatggcat tatagggttt attctttgga agaatgtagg tgtaacttgt
    42721 atagggaatg taccaccaga agaaccaatc tgaacgacta atagtactat tgcaattgct
    42781 tttcctacat ttccaaatac agaaactaaa gaatacacta taaagttaaa taccatacta
    42841 gtaaacataa gcagaactat caataaaatt ggatgttttg ctgttactcc taacaataat
    42901 atatctccag ttcctattat aaaaccttgg acaagagcta tacttaaaaa agtaaggcct
    42961 cttccaaagt aaatttcata aggtttatag tttccatgta cagatgtaga caatagtgct
    43021 gaaataagta atataccaac ccatgtagaa agaacactat aaaatggtgt cattgcagaa
    43081 ccataatttt caattggata taatttctct gttttcacct caacaggttc ttttaagaaa
    43141 ttagactttg tcaatatatc actttcaagc aagctgacta attttttcat atcttcacca
    43201 ttactaattt tgcttaaagt atcaatcaaa tcatccaaca ttccttttgc taaaggaagt
    43261 ctttctctta tcaatgatat actttcctgt gcatttcctg aaagttttag agaagtagta
    43321 agtatttctt caacctttgg aagttttgct tctgccttat ctaaaacagt aattatatca
    43381 tttgctactt ttatactgtt tgcaaatata ctatttatag gttttgatat ttttgagtca
    43441 aaattattta aaatatttaa attaattctt ccaataccat ttgatagact taaaacatta
    43501 ttcaaagcac ttatagatgg ttgttgtcca gatataactt tgtttttaat atcatttaat
    43561 gttgatatag atgaatctat tttattgcta gagtcttcaa gattatctat gacatcatcc
    43621 aatctattat ttgatgtaag ttggtttaat ttagttaaaa aatccaccaa agtatcattt
    43681 aaagattgca aattagaaag tttttctgat aaattatcta tcaacttagg tacatcttca
    43741 ctgccactat ttactgcatc aattaaattt aatgtaagag aagaagcaga agatgaaagg
    43801 tcaaccatta aatttaagtc agacttaata agaggagaaa gttcgtctaa attatcattt
    43861 gtatcctcta agaatttttt taagtcactt gataatagtt ttgtatcatt cagagtcttt
    43921 ttaattgtag gtaaatcaga tttaatatct ttaactgtat cagataattt tgaagtagca
    43981 tcagaagcta aatcaacagt cttatttata tggtcaaatc tcttttgaag gtcaataagg
    44041 gaattttcaa cttttgtcaa ttttggaaga ctgtgttcaa ttcctgcacc aactccgttt
    44101 gatataccaa gaacgatttc actaactgtt tttactatag tctgattaac ctgtagttgt
    44161 attgtagaag cacctttatc tgtaatcttt ggtgcaactg catttatttt ttcattaaca
    44221 gtatagataa tttcgccttt tttaacatca tctgtaatta aagatgtcaa atcttttgta
    44281 aaattttttg gaatcttaag tgatgcataa taagtacctt ttttaacacc ttcaagagca
    44341 gttttttcat ctacaaactg ccaacctaaa ctcttgttat ctttgagttg ttcaattaat
    44401 tggtctccta cattaatctt ttgtcctgct atttcatttc ctttatcttc atttgttact
    44461 gctacaagca tattagcagt gcttccataa gggtcccaag atgcctttat attgaaccaa
    44521 gcatacagag atggtaaaaa agcaagacct aaaactatta caagtacggc ataattgcca
    44581 cgtatatctt ttaggtcact tttaaaaatt tctaatatat tttttaaacc ctttgaaggt
    44641 cttaaattct tgatattatt ccagtttaaa atttctttta aactattagt ttttttcaaa
    44701 tgtctcacct cctaaaatat tttgataaag aaaaaagtta gatttataat caattttaaa
    44761 ttatattact ttttacacaa atagtaaagt taaaattttg tcttaat
//
LOCUS       DAEPHU010000026        44604 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 01A10CD0081
            SAMN05941466-rid12468953.denovo.026, whole genome shotgun sequence.
ACCESSION   DAEPHU010000026 DAEPHU010000000
VERSION     DAEPHU010000026.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941466
            Sequence Read Archive: SRR6291087
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 44604)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 44604)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068158.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 22:43:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,892
            CDSs (total)                      :: 3,805
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 87
            rRNAs                             :: 8, 1, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 55
            CDSs (without protein)            :: 55
            Pseudo Genes (ambiguous residues) :: 0 of 55
            Pseudo Genes (frameshifted)       :: 21 of 55
            Pseudo Genes (incomplete)         :: 28 of 55
            Pseudo Genes (internal stop)      :: 16 of 55
            Pseudo Genes (multiple problems)  :: 8 of 55
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..44604
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941466-rid12468953.denovo.026"
                     /strain="01A10CD0081"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            94..996
                     /locus_tag="KR231_001545"
     CDS             94..996
                     /locus_tag="KR231_001545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HBH0003927.1"
                     /translation="MFKKNKKQTENVKEKKVRTVKVGTHKKTVIALWVVLIASVSFGV
                     YKNFTAIDQHTTHEKEVIELRLQDTNGIENFVKNFAKSYYTWSNSKEAIDARTQAISG
                     YLTKELQDLNMDTIRTDIPTSSAITDVIVWSIEQSGTDTFSATYEVDQQIKEGEQTTA
                     VKATYTVKVHVDAGGNMVIIQNPTLAPAIEKSDYEPKTPEADASVDADTINDATAFLE
                     TFFKLYPTATEKELAYYVSGNVLESIGRDYLYSELVNPIFTVDGDNVKVKVAVKFIDN
                     QTKATQVSQFELVLHKESNWKIIG"
     gene            complement(1195..1530)
                     /locus_tag="KR231_001546"
     CDS             complement(1195..1530)
                     /locus_tag="KR231_001546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0003928.1"
                     /translation="MTHMSADKLLLGFHLDHVSNLNELLRKVAHNNICIMSDRMTKVA
                     VWKPSVKTIQLVCMEYLNYIIDHSVIYEKIQCANWNGTEETNSIFNNSPSPLITLIYS
                     CDLQQNKTT"
     gene            1480..1689
                     /locus_tag="KR231_001547"
     CDS             1480..1689
                     /locus_tag="KR231_001547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0003929.1"
                     /translation="MVKVKTKKKFVSTHMCQGEMPIYVRERYEKMLAVSIRAPNLEGM
                     VENFDKDLSRPNETDLIELKNAISK"
     gene            1782..4445
                     /gene="mgtA"
                     /locus_tag="KR231_001548"
     CDS             1782..4445
                     /gene="mgtA"
                     /locus_tag="KR231_001548"
                     /EC_number="7.2.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016440611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium-translocating P-type ATPase"
                     /protein_id="HBH0003930.1"
                     /translation="MSKATLFDSRIKKYAYCRTSEIYRDIGSSPDGLSIEQIGSMREK
                     YGANSFNGRKNDTTMQRLRRAFINPFHVILFVLGIVSLVTDVFVASNFARNATTAIII
                     FSMIVISGVIRLIQELRAKSAAAQLDRLVHESVTVRRDGKLIEIPGEELVVGDIVLFS
                     AGDRVPADIRLTKITDLFISQAAITGESAIIEKSCRKLSYGEQDTLTQLENLAFMATT
                     VISGKGEGIVLAVGKDTLYGGFTKPDSDDKNSFKKGADSIAWVMIRFMAILVPIVFIL
                     LGITDGKWMESFAFALSVAVGLMPEMLPMVITACLAKGSLAMSKKQTIIKDINAMQSF
                     GSMDVLCMDKTGTLTNESILLEYYMDIFGNENAEVLDLAYLNSCYHSGVCNTIDNAIL
                     ACNTMPGREAHYANLLTKFQKADEIPFDYARKFVSTLVQDSNGNSQLIMKGDIEHIFS
                     RCNHVEYRGKLLPMGQDARQSVSSVVGEMLQDGMKVIAVARKNVGAQKKITPDDEWGM
                     TLVGYLSFFDAPKQTAKESVTALKRLKVIPKILTGDQAAIAVSVCRRVGIYTERILTG
                     TQLDEMTDCELKKAVEHTHVFAELTPGHKVRLVSAMQDNGHSVGFLGDGVNDIPALNE
                     ANVGISVDTAVDAAKDAADVVLLQKDLNVLEQGVMEGRKTFTNMLKYIKITASSNFGN
                     IFSIICASAFLPFLPMTSIQILLLNLLYDTLCIVLPWDNVDEEEMLSPRDWSGKTLRQ
                     FMLSFGPISSLFDIVTFLFLYYFLCPMLCGGATYLQLTDPSLQLQYVALFQTGWFLES
                     MWTQVLILHFLRTSKIPFFQSRASAPVISITLVGIIAFTSLTFVGGASLFGLTKLPLW
                     YFVFLLLVVSLYMLLNSVAKYFYKKKYQELI"
     gene            4461..4964
                     /locus_tag="KR231_001549"
     CDS             4461..4964
                     /locus_tag="KR231_001549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006566797.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HBH0003931.1"
                     /translation="MKKNISYIPMDSALEIWLLEKLLRDPPDSDCAKDLLSGIQEMIR
                     GEVSSLLLGASEESDWPVGTLSDRILAGDLEIYPRGRKVLIKGSEVNLTPKEFDILYF
                     LVQNKGEVFTKEQIYRAVWEEDYILDNSNIMAFIRKLRKKIEPAPDCPTYILTIWGIG
                     YKFNDQI"
     gene            5102..5779
                     /locus_tag="KR231_001550"
     CDS             5102..5779
                     /locus_tag="KR231_001550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018597221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MgtC/SapB family protein"
                     /protein_id="HBH0003932.1"
                     /translation="MFYTDFILRIALSLTLGFLIGLERQLTGHPAGIRINVLICMGTS
                     FFTLFPMLYGSDQVFRVGSSIISGVGFLCSGVIFKDRGTVRGMNTAATLWCTAAIGIL
                     ASTGMYAMAITAATILIGSNLILRPFARKFHPITSSDESEKQYRISVTCQEKAEQDIR
                     LLLINSNSCKTLFLNNLESGDVVGDKVEIVAEYCSVGKSKNNILEGIVGQVLVIPEVI
                     SAGWEVL"
     gene            6026..6337
                     /locus_tag="KR231_001551"
     CDS             6026..6337
                     /locus_tag="KR231_001551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3784 domain-containing protein"
                     /protein_id="HBH0003933.1"
                     /translation="MDFTCIFFGILFTLAGFWLAFGKGYRHLSLWKNMPQEEKDKINI
                     VPLCRNVGEMIALNGIIFLMKGFLPGFSNHWFVFAIIAWLIVAGFDVWYIEKSVRYRN
                     Q"
     gene            6503..9268
                     /gene="mgtA"
                     /locus_tag="KR231_001552"
     CDS             6503..9268
                     /gene="mgtA"
                     /locus_tag="KR231_001552"
                     /EC_number="7.2.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002571344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium-translocating P-type ATPase"
                     /protein_id="HBH0003934.1"
                     /translation="MNKKENRMAIRQTVEKAVIRDEQNRRIQFAATNPIKEVLKKLHT
                     TLRGLEVDEVSVSRAKYGTNKVTHEKKKSLAKRLVGAFINPFTAILFCLALVSTITDM
                     IFPYFSLFGSVPEDFDSLTVVIILTMVFISGTLRFVQESRSGNAAEKLLAMITTTCTV
                     TRRNYEKKELPMDDLVVGDIVHLSAGDMIPADVRILDAKDLFVSQASLTGESEPIEKT
                     PNVSAQKESVTDYTNIAFMGSNVISGSATAVVVCVGDHTLFGSMASAVAGEAVETSFT
                     KGVNAVSWVLIRFMLIMVPLVFFVNGITKGDWLAAFLFGVSIAVGLTPEMLPMIVTTC
                     LAKGAVSMSKKQTIVKNLNSIQNFGAIDILCTDKTGTLTQDKVVLEYHLNVNGEDDTR
                     VLRHAYLNSYFQTGYKNLMDLAIIHKTEEEEAADSRLIDLSENYVKVDEIPFDFTRRR
                     LTTVVQDNKGKTQMVTKGAVEEMLSICAFAECNGGVQPLTDDVRYRILETVDNLNDKG
                     FRVLAIAQKSNPSPIGAFGVKDECDMVLIGYLAFLDPPKESTADAIKALKDHGVITKI
                     LTGDNDKVTRTICKQVGLEVRNMLLGSDLEQMGDAELARVAESTDVFAKLTPDQKARV
                     VSVLRENGHTVGFMGDGINDAAAMKAADIGISVDTAVDVAKESADIILLEKDLMVLEQ
                     GIIEGRKTYANMIKYIKMTASSNFGNMFSVLAASALLPFLPMMSVHLIFLNLIYDLSC
                     TAIPWDNVDEEFITKPRKWDASSVGSFMIWIGPTSSIFDFTTYIFMYFVFCPLFVSNG
                     VLFNDLPAHFSGAELAMLQAQYIGMFQAGWFVESMWSQTLVIHMIRTPKLPFVQSRAS
                     APVTLLTMTGIIVLTIIPFTVFGTMLGFVALPAAYFAYLIPCILLYMTLATSLKKAYV
                     RHFGELL"
     gene            9281..9448
                     /locus_tag="KR231_001553"
     CDS             9281..9448
                     /locus_tag="KR231_001553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002587909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0003935.1"
                     /translation="MNWKELWMTLFGTTEWLGLNIGFWVAMAVVLLIVIVMNVVFWSM
                     KPKKDTKESYK"
     gene            10499..10798
                     /locus_tag="KR231_001554"
     CDS             10499..10798
                     /locus_tag="KR231_001554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HBH0003936.1"
                     /translation="MKHLHIQQLSTIGSSLKKHLNSTEHNAPICGFLQHITGIICLAQ
                     DQYVCIALVLFYCIKLFQKIFAVGYQIPPFMVSVSAKRGRSLFALATFAGKGVRL"
     gene            10795..11211
                     /locus_tag="KR231_001555"
     CDS             10795..11211
                     /locus_tag="KR231_001555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002592281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HBH0003937.1"
                     /translation="MKPSSFEGAIRLQFDCLARKVVGRTVKNYDRELGRRARRETPFC
                     DLSEMELNQIGAMDEYCVEFTSFDVFGSEVHIYDERLCEAIKELTESRRNILLMSYFL
                     EMTDAEIAEVMEMERFSVCRNRLHTLKLIKDMYEEE"
     gene            11216..11455
                     /locus_tag="KR231_001556"
     CDS             11216..11455
                     /locus_tag="KR231_001556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002592280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBH0003938.1"
                     /translation="MMKSTKKCPSFSTISSAADGNEVAIEKILNHYDAYISKASLRPF
                     YDEHGNMYIVLDMELKGRIRAALIKVILGFEVKVK"
     gene            11774..11917
                     /locus_tag="KR231_001557"
     CDS             11774..11917
                     /locus_tag="KR231_001557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HBH0003939.1"
                     /translation="MNNIIRYSMQIAMLKQLLARKLISEKEYTLVKQRLMKDYKVLSD
                     ITA"
     gene            11980..13740
                     /locus_tag="KR231_001558"
     CDS             11980..13740
                     /locus_tag="KR231_001558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HBH0003940.1"
                     /translation="MQEVEVIKAKNVLARQARGKAIERLRVAAYCRVSTDSEDQLNSY
                     KSQVQYYTDMIKKNKEWVLADIYADEAITGTQVTKREDFQRMINDCMNGEIDMVFTKS
                     ISRFARNTLDTLKYVRMLKERNIAVYFEDEKINTLTMDGELLLVVLSSVAQQEVENIS
                     ANVKKGLKMKMKRGELVGFQGCIGYDYHPEDKTITVNQEEAEIVRYIFNRYVDGAGGS
                     VIGQELESLGYKTKYGSSTWAPSTVIGIIKNEKYKGDILLGKTFTVDPISKRRLENMG
                     EEDKFYMKDHHEPIISEEVFEKAQEILNRRNKNRTTVGSGKREKYSRKYAFSCMLECG
                     FCGGTLTRRNWHSGSKYSKVIWQCVTATKKGKKFCKHSKGIPETAIEEAFVESYRLLC
                     DDNKDVLEEFLQRMDDTLSSSVVSKQLAKAEKEIDALEKKKSKLVDMRLEEIIDKETY
                     ESKYADLVSKQEQLVEERQKLQETSDNEKDIKKRLKEFKKTLEQNEVLDKFDRYVFES
                     IVEKVIVGGLDENGNVDPAQLTFVYKTGLKNSVDGAKFKTQRKNARGRHRTNELCSHD
                     SNEVDKMCSDSSNDTCGNCS"
     gene            complement(14229..14867)
                     /locus_tag="KR231_001559"
     CDS             complement(14229..14867)
                     /locus_tag="KR231_001559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0003941.1"
                     /translation="MSNQRKDFDITNDMFQESIPITTKIILEDMPSNDELNHVFSKGC
                     ERKMKKRKIVLITLLLIGVLLLGSILYNLFLGKTANISMLKESWNFDIPIPNKEIEVF
                     DTQDSINGDGQSYFIQGFSEKNFKKVFNLKGGIVVSKDNINEIEKYIDKFKRDSVNIN
                     KSNKNKIEEDFKKYKLEVKKDDKYIYKRNYENYVVLIIKKDEQKLYSLIWNQ"
     gene            complement(15277..15453)
                     /locus_tag="KR231_001560"
     CDS             complement(15277..15453)
                     /locus_tag="KR231_001560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0003942.1"
                     /translation="MFRDKMDRCTHMLTAYIGSSYDYCDFIDTQLDDFILEYGENVVE
                     SCLHQVMVLVSKYN"
     regulatory      complement(15507..15603)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01051"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="cyclic di-GMP riboswitch class I; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="cyclic di-GMP"
                     /db_xref="RFAM:RF01051"
     gene            16400..16801
                     /locus_tag="KR231_001561"
     CDS             16400..16801
                     /locus_tag="KR231_001561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429137.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNHCP domain-containing protein"
                     /protein_id="HBH0003943.1"
                     /translation="MNYKNRKRAYYQENSCMDNFICKNCGCLVVPEGAGTQHRNHCPH
                     CLHSLHVDIIPGDRAADCDANMEPIGVWVRKNGEWAIIHRCTRCGHLSSNRIAADDNS
                     VKLMSIALKPLAQPPFPLERIIEKLEKEETE"
     gene            16798..17865
                     /gene="rsgA"
                     /locus_tag="KR231_001562"
     CDS             16798..17865
                     /gene="rsgA"
                     /locus_tag="KR231_001562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898525.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome small subunit-dependent GTPase A"
                     /protein_id="HBH0003944.1"
                     /translation="MNGMKQINLQDYGLNRNFITQSMEYHDLYLARIISQEKNFYQAV
                     CVNGVLFAEVSGKLRFEATIQSDFPTVGDFVMLDRCNNKNGNAIIHHVLHRKSLFVRK
                     AAGKVNEEQVVAANIDIVFLCMSLNKDFNIHRLERYLSLTWESGAIPVVVLTKSDLCD
                     NVHRKLQVVNSIALGVDVVVTSSIEPDGYKQISKYIKPGCTVALLGSSGVGKSSLINC
                     LMGGEFLNTKEIRIDDDKGRHATTRRELFLISGGGIVIDTPGMRELGMWDVSEGLDKS
                     FADIEAYFGKCHFRNCTHTSEPGCAIWEAIAHQELSPKRWESYRRLKTEAVFADNKSE
                     YLAKKEKKFKNISKINKKIRR"
     gene            18401..19099
                     /locus_tag="KR231_001563"
     CDS             18401..19099
                     /locus_tag="KR231_001563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0003945.1"
                     /translation="MKISSQYRSQYSFRYESNINNTRINESMVKKNETVGKDTYLSNI
                     MKQKQELNDRIRDLKYRQEVYTKKINDAIKNLCKSEIRETTNNFSNIEIGIKNSIIEE
                     KNKSTMLDENSTYLNTNDEKESLITKESNEKIEEEILNDEKLEELEQKKDYKEDSNKK
                     EKVSEDLSLVGKTREELENMLKNFINLTQEEIMKLESRIEKLDKNAEEYKQNSKTNIF
                     DKTDEQKKHINVLI"
     gene            19277..20167
                     /locus_tag="KR231_001564"
     CDS             19277..20167
                     /locus_tag="KR231_001564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0003946.1"
                     /translation="MKKNILTTMITMIIILMMSMTVMAEPYQEDETSSLKKQSANERN
                     QTNIGTMDGRVQTNAISKGANYDPKYPLKGMLTQLGLNTTGKEGWDLLYGGNPNGVEL
                     RADGKYYYINKGMEGLGFYAAALSGGSYQRIGFGKLDPIEVIADGNWISYKQAQDTLT
                     VIRNFLNSFDWRNASEMERANRAAKLVTEAKYADSKYCNIVYGNLVDKRGVCGSFASS
                     FHLLTRLMGMDSLSILNPSLNHAWNYIQIDGKWYRFDGSEISAFGGSLDFDYRKLKDA
                     TREMTTYYDAKALSILGFNQ"
     gene            complement(20560..21516)
                     /locus_tag="KR231_001565"
     CDS             complement(20560..21516)
                     /locus_tag="KR231_001565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diguanylate cyclase"
                     /protein_id="HBH0003947.1"
                     /translation="MENNTIQKQLRDLSKKIWHIYILNPEEENLKFIISLLDDNLALI
                     GTGKHEFYETLEEFIIGLEKDQTESEQIDFEIIDEWYSCTKVTDEAFIVYGTLWVIEK
                     DYLEKDIYVEMDTRFTMVYRVTDDMIKLIHVHHSIPNFDQMKDEYYPKTITEKAQEAL
                     AMANEFKLKSEKDLMTGLYNRHFFEVHIKEMLKTVSHGYFYIFDLDNFKQVNDIFGHV
                     RGDEILIHFSNILTKVFVNDAIIGRLGGDEFAVFEYSNQSKENVENKAKKVLELCLES
                     NSCSIGISKLENNSDTFQSLYKQSDYALYYSKRNNKGNFSWF"
     gene            22219..23214
                     /locus_tag="KR231_001566"
     CDS             22219..23214
                     /locus_tag="KR231_001566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBH0003948.1"
                     /translation="MSIIELNELTKSYRRFEKKAGFMGSVKSLFNRKYTEKTAISSFD
                     LKIEEGEFVGLIGQNGAGKTTLIKMLTGIIAPSSGEISVMGYYPNKLENNFKKQYAVV
                     MGQKSQLFFELTPADTFLLFKELYDISNEEYKKNLDYFIELFEVSDYLNVQVRTLSLG
                     ERMKMELIVALLHNPKILFLDEPTIGLDAIAQKQIRYFLKEVNETKGTTIILTSHYME
                     DIKSLCSRSIVVENSRKIYDGSTEKLFNYFQKYKKITVSFSNETNIVFPKDCKVVEQT
                     NHKISVIVPKERGNETIKWIFDKYDVKDVMIEEEDIGSIVERIYKKGSDEYYEQL"
     gene            23192..24055
                     /locus_tag="KR231_001567"
     CDS             23192..24055
                     /locus_tag="KR231_001567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-2 family transporter protein"
                     /protein_id="HBH0003949.1"
                     /translation="MSIMSNYNEASSNDSMFYKFKQSIRRYYEVAKINFKVQLIWRFD
                     VVVNMVFTIVKILFAYILWKAIFGENKIVSGFTFNSMLSYYIISSFLAGIDMSKSTSE
                     EICNRVKLGTFSKYMIIPINVQNYFIAKNFGMTCFYFVFNMISAFVWIFIFKIDFAFT
                     SNPVQILISILMIFLGFIFMMKLHFFIGILSFKFLEISFLKMIIENIVEFITGTMIPL
                     VLLPETIVTVMKVFPFYYTTYLPSMLLIGRNSNEAIQGLIILALWVLFFSVVNKVMYK
                     RMRTLFDGVGI"
     gene            24052..24846
                     /locus_tag="KR231_001568"
     CDS             24052..24846
                     /locus_tag="KR231_001568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-2 family transporter protein"
                     /protein_id="HBH0003950.1"
                     /translation="MMKKNLKIIFMLLKMKLSKMMVFRFDFFGAFFVDSSLFILQLLM
                     FNSIYSHVDSIGGWQQGEMLIFIGTFSLINAINMTIFFFGIYDIPRKIQEGELDYYIT
                     KPLDPLFRLTFENINIGSSPLILASILIVLYGISELNSEITLVMIIIYIFMVLLMTLL
                     FYDVCIILRTVSFFVISSSAIMRLEDNLLPMNMKIPGVIYEGIFKVLFYLILPYGIMS
                     TIPTQILAGTITINGLIYSILIVFLFTLFMWRFWKLGMRHYKSASS"
     gene            25131..26510
                     /locus_tag="KR231_001569"
     CDS             25131..26510
                     /locus_tag="KR231_001569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HBH0003951.1"
                     /translation="MSDVYYSENHEQDNLYEQDNLLAQRFNLFTLLKFAFPTIFMMIF
                     MGLYTIVDTIFVSRFINTNALSAINIVCPIINLIVGIGTMLATGGSAIVARKMGNGDI
                     EGANKAFSLIVLSGVVIGVIITGIGIVFMDYIIIWLGASEVLIKYCRSYLFIILVFAS
                     ANILQVLFQCLFVTAGKPQFGLWLVLGAGCANIILDYVFIVLLQMGISGAALATGVGY
                     LIPTISGMVFFSKNKGLLKFCIPRLDKRILFEACFNGSSEMVGQLSTAVTTFLFNAMM
                     MKLIGEDGVAAITIIIYSQFLLTSLYIGFSMGVAPIISYNYGSENNTQLNHVFKICIL
                     FISVASLLVFIFSISCSPIIVEIFSQRGSRVYEIARSGFYIFSFSFIFCGYNIFTSSM
                     FTALSNGKVSAILSFLRTFGFITIGLLILPNILNINGIWLAVPSAEILTLFLTVFCIF
                     KYKNRYKYM"
     gene            26958..27671
                     /locus_tag="KR231_001570"
     CDS             26958..27671
                     /locus_tag="KR231_001570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBH0003952.1"
                     /translation="MDTCFNKKILLVDDEKDIVDLIEEVLINDGFKNIIKAYNGLDAI
                     SLCKIACPDVVILDIMLPDIDGIEVCKKIREFSYCSILFLSSKNDDIDKILGLSSGGD
                     DYITKPFSPREIAFRVKAQLRRQQYQSIVPSDSEVIKIGDITIDIEGNRVYKDRNEIE
                     LTGREYHLLSYMAQNVNKIIGKERLYEQVWGVYSSICDNTIMVHIRHIREKIEDNPSN
                     PKILITVKGLGYKLVNRID"
     gene            complement(27943..29481)
                     /locus_tag="KR231_001571"
     CDS             complement(27943..29481)
                     /locus_tag="KR231_001571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HBH0003953.1"
                     /translation="MSLLKVTNLSQCFMDKSLYEKANFDLFKGEHIGVVGQNGTGKST
                     LIKILLGEVVPDSGEIKWQPNINIGHLDQYAEINRDTTISLYLHTAFEELYKIEKEMN
                     LLYQKSAISENEQYLIKASDYQEQLIASNFYSIDNEINKIANGLGLDSIGMNRVVREL
                     SGGQRAKVILAKLLLSNHDVLLLDEPTNFLDKEHVEWLSNYLNTFNGAFIVVSHDFDF
                     LEKISTGILDIEFGMIKKYHGKYSEFLKQKSHLREDYIRRYQAQQKKIEKEETFIRKN
                     KAGVNSKIARGRQKQLDKIERIAPPSFTGKPNIQFSEIEISAQNALTITNLEVGYYYS
                     LLPKLNFSVDGGQKIVITGFNGIGKSTLLKTLVKDIPRISGDFQFSEQVKIGYYEQDL
                     KWENPDKTPLQIVADKYPKLNTKEIRRHLARCGVKEEHVSRSVSTLSGGEQSKVKLCC
                     MMLSPCNFLILDEPTNHFDAETKDALQNALKQFRGSIILVSHEEKFYKGWIDKVFNIE
                     KQLV"
     gene            30363..30818
                     /locus_tag="KR231_001572"
     CDS             30363..30818
                     /locus_tag="KR231_001572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Lrp/AsnC family transcriptional regulator"
                     /protein_id="HBH0003954.1"
                     /translation="MDEIDLKIINSLKKNSRASTSEISRQINLSVPAVSERIRKIEQS
                     NLIQKYTIQINREKTKYKLLAFIFINTDLSKSMKEFKKTILEYDTVLECHHISGEYDY
                     LIKVLAEDTSNLEEFISVTLKEIGGIQKANTTIVLSTIKEEFNTIKDIF"
     gene            30867..31451
                     /locus_tag="KR231_001573"
     CDS             30867..31451
                     /locus_tag="KR231_001573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DJ-1/PfpI family protein"
                     /protein_id="HBH0003955.1"
                     /translation="MKVLVFLAKGFETMEFSVFVDVMGWARNDYGHDIDVVTCGFKKQ
                     VMSTFNIQVLVDKTIEEVCVDDYDALAIPGGFEEFGFYDEAYDSSFLNLIREFNSKEK
                     IIASICVAALPVGKSGVLKNRKATTYHLKNGKRQRQLSEFDVNVVNEPIVVDKNIITS
                     YCPETAPHVAFKLLEMLTSKEQMDEVKLAMGFKL"
     gene            complement(31456..31779)
                     /locus_tag="KR231_001574"
     CDS             complement(31456..31779)
                     /locus_tag="KR231_001574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBH0003956.1"
                     /translation="MKKCLDNYSCPIEATLALIGGKYKTLILWHLKDTILRFNELKKL
                     IPKATPKMLTQQLRELESDGLIIRVVYPVVPPKVEYSLSDFGKSIIPILDSMCDWGSD
                     YLENL"
     gene            31931..32449
                     /locus_tag="KR231_001575"
     CDS             31931..32449
                     /locus_tag="KR231_001575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HBH0003957.1"
                     /translation="MNFVELAKKRYSCRNYQDRKVEKEKLEKVLDVARIAPTGGNRQP
                     QRLIVIQEKEGINKLSKAANIYDAPLAILVCGDKDKVWTRPFDGKQLTDIDTSIVTDH
                     MMLQATELGLASVWVCYFNPDIIREEFSLPDNLEPINILLMGYESKIPESPERHEKTR
                     VPLSEIVSYETL"
     gene            complement(32625..33293)
                     /locus_tag="KR231_001576"
     CDS             complement(32625..33293)
                     /locus_tag="KR231_001576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA-binding protein"
                     /protein_id="HBH0003958.1"
                     /translation="MLEVSHKVKEIYPNIKFGVMVINITHSKPNKENFLVLKNSTIKN
                     IIEQHPEYNRKEKIKTEPVSSYIKYYKKFKKTYPVLLQLESILLKSKGIPDVGVTIES
                     MFLAELKNLLLTAGHDLDKMELPLKIELANGSEHFYGIGGKEHILTKDDLFLSDNIGI
                     LSSILNGPDNRTAITKDTKNIMYFVYGPDKISEKQIQDHLNDIKHYISSAFPDLKVNS
                     IDIF"
     gene            33408..34823
                     /locus_tag="KR231_001577"
     CDS             33408..34823
                     /locus_tag="KR231_001577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HBH0003959.1"
                     /translation="MWITINRNSNISLSRQIYCEIKDMILDGSLKFEQKLPSSRTLSK
                     ELSVSRNTVLDAYNQLIAEGYLETRNGYGTIVAKGISGHKVDFKLNDTFRDEKDLHTN
                     KQKNYIDFRSGVPELKLFPRKELSKLYKQILYDLSDSDFRYGSTAGVWVLRVEISKYL
                     FRTRGIRCNPKNIMIVSGSTQGLSLISQLLYKSNKKVAVEDPIHKGLLKVISSIGYSV
                     VGIKVDDKGMNTNLIKSIKGISFVYTTPSHQYPLGGILPIQRRLELIKCATENDYYII
                     EDDYDSEFRYEGQPISSLYELSPNKVIYIGSFSKILSPAIRVGFMLLPDNILESYKTL
                     KMYSDVHTETILQHVLAEFIGNGGLEKYIFRMKKLYNRKRKYLIKVLNTEFKNEFKIK
                     GEAAGLHIVAHFYNVKFTESLIHKIFEAGIKVYPIQQYAIENILEYDYEIILGYAHLS
                     FDEIEKGVKILSKIIHMNQGT"
     gene            35046..35504
                     /locus_tag="KR231_001578"
     CDS             35046..35504
                     /locus_tag="KR231_001578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBH0003960.1"
                     /translation="MEIIDYIEENLTENLNLDKIAYIANYSKYHLHRMFTNVVGCTIH
                     QYIQRRRLTEAARQLIFTDKYIIDIAITVGYSTHQSFTLAFRNLYKESPQVYRNKDEF
                     YPIQQRFVLNLNHQIQSEKCISYANMNYKQRRDEINSYLNFNINCEVKVA"
     gene            35501..36085
                     /gene="clpP"
                     /locus_tag="KR231_001579"
     CDS             35501..36085
                     /gene="clpP"
                     /locus_tag="KR231_001579"
                     /EC_number="3.4.21.92"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp endopeptidase proteolytic
                     subunit ClpP"
                     /protein_id="HBH0003961.1"
                     /translation="MSLVPHVIEQTGQGERSYDIYSKLLKDRIIFIGEEINDAIASLV
                     VAQLLFLESEDPDSDIIIYINSPGGSATSGFAIYDTMNYVRCDVSTICIGMAASMSAF
                     LLAGGTHGKRCALPNSEIMIHQPMGGAKGQATDVKIAVDNILKIKERLDKILSENTGK
                     SIEDIRRDTDRDNFMTALEAKEYGLIDYIMNRNE"
     gene            36397..37473
                     /locus_tag="KR231_001580"
     CDS             36397..37473
                     /locus_tag="KR231_001580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HBH0003962.1"
                     /translation="MITISLCMIVKNEEEVIGRCLECVKDIVDEIIIVDTGSTDSTKE
                     IVSKYTDMVYDFEWIDDFSAARNFSFSKASKDYTMWLDADDIILEADREKLLKIKESL
                     DTSIDIVMAKYNVSFDENGNPTLSYYRERLFKRSSNHKWVDPIHEVVPLFGEVFYSDI
                     AISHKKLHRQDPLRNLRIFEKMISEGKTLEPRHQFYYSRELYYNARYKEAIEGFTKFL
                     DSSRGWIEDCISACRDLATCYYLINDEKSALYSLFRSFEFDEPRAEICCDIGKHMFDR
                     QKYKEAIFWYKVALTRDKNDTNGGFKSNDCYGYIPSIQLSVCYDRLGESDKAIYYHEK
                     TKEIKPNDSAVLHNENYFSKFKNS"
     gene            37540..39612
                     /gene="bclA3"
                     /locus_tag="KR231_001581"
     CDS             37540..39612
                     /gene="bclA3"
                     /locus_tag="KR231_001581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="collagen-like exosporium glycoprotein BclA3"
                     /protein_id="HBH0003963.1"
                     /translation="MLLIMSRNKYFGPFDDNDYNNGYDKYDDCNNGRDDYNSCDCHHC
                     CPPSCVGPTGPMGPRGRTGPTGPTGPTGPGVGATGPTGPTGPTGPTGNTGNTGATGLR
                     GPTGATGATGPTGATGAIGFGVTGPTGPTGATGATGADGVTGPTGPTGATGADGITGP
                     TGATGATGFGVTGPTGPTGATGVGVTGATGLIGPTGATGTPGATGPTGAIGATGIGIT
                     GPTGATGATGADGATGVTGPTGPTGATGADGVTGPTGATGATGIGITGPTGPTGATGI
                     GITGATGLIGPTGATGTPGATGPTGATGPTGVGVTGATGATGATGADGATGVTGPTGA
                     TGATGANGLVGPTGATGAAGTPGATGPTGATGPTGVGITGATGATGATGPTGADGATG
                     PTGATGNTGADGVAGPTGATGATGNTGADGATGPTGATGATGADGATGPTGATGATGV
                     AGATGATGPTGATGATGADGATGPTGATGATGADGATGPTGATGATGVTGATGPTGPT
                     GATGATGATGASAIIPFASGIPLSLTTIAGGLVGTPGFVGFGSSAPGLSIVGGVIDLT
                     NAAGTLTNFAFSMPRDGTITSISAYFSTTAALSLVGSTITITATLYQSTAPNNSFTAV
                     PGATVTLAPPLTGILSVGSISSGIVTGLNIAATAQTRFLLVFTATASGLSLVNTVAGY
                     ASAGIAIN"
     gene            39781..40542
                     /locus_tag="KR231_001582"
     CDS             39781..40542
                     /locus_tag="KR231_001582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="epoxyqueuosine reductase"
                     /protein_id="HBH0003964.1"
                     /translation="MKNKIEISMNNFVKNYHKSNNITTKWQELLFAYASAEDDMFQKL
                     KSVVGTSHAMPKDFLENGKTIITYFIPFDESVNNSNIGGFECSEIWARAYIETNMLIS
                     NLNDFLCEELEKIGANSYAIPGSYNFDSEKLVSDWSQRHVAFIAGLGTFGLNNMLITE
                     KGCCGRIGSIITSLELEPTKRPENEYCLYKHNNSCKKCVNKCVKEALKEDGFNRNKCY
                     EMCMINEKKYTYIGGCDICGKCIVGVPCSVINPSR"
     gene            40851..41129
                     /locus_tag="KR231_001583"
     CDS             40851..41129
                     /locus_tag="KR231_001583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0003965.1"
                     /translation="MSYKKAIHILPEELLELIQEYVDGECIYIPRKSNNKKEWGSNTP
                     TREELSIRNMQIYEDYQVGYDLQYLSEKYYLSLKSIQRIVLQEKRKDI"
     gene            41422..41997
                     /locus_tag="KR231_001584"
     CDS             41422..41997
                     /locus_tag="KR231_001584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1062 domain-containing protein"
                     /protein_id="HBH0003966.1"
                     /translation="MKKITWEVEYISQLPVIRYCKKCGKKTEYICSGLFRVNAQHKYL
                     DIWLIYKCSNCDSTWNSTIYSRVNPKSLNPEILEQFHTNDYNLVKQYAMNMELLHRNG
                     AEVGIPEYKIVGQEININDLTQVHIISKYPCQLKVSTLLREKLGLSRKVFDEMLDCGI
                     IRSNSGVDLKKGKLNYEIMLDIGKEKQKSSN"
     gene            complement(42103..42936)
                     /locus_tag="KR231_001585"
     CDS             complement(42103..42936)
                     /locus_tag="KR231_001585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prenyltransferase"
                     /protein_id="HBH0003967.1"
                     /translation="MNVENQSLSDIEIILSHRYDNGADYWTTPDKRLIKGSPFSTLDS
                     VLYLLELGVNPDDTLLKECADLIFSTWREDGRFKLYPNGGIYPCHTANAANVLCHMGY
                     ASDIRMQKTFQHFLDTQYTDGGWRCNKFSFGRGPETEYSNPLPTLNILNAFRFSNYLN
                     KESKLDKAVDFLLDHWTIKKPIGPCHYGIGTLFMQVEYPFRNYNLFLYVYVLSFYNRA
                     KKDKRFLEALKILESKMIGNKIVVERVVPKLSKLSFCKKGESSEIATTHYYEILKNLE
                     K"
     gene            complement(43004..43633)
                     /locus_tag="KR231_001586"
     CDS             complement(43004..43633)
                     /locus_tag="KR231_001586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3786 domain-containing protein"
                     /protein_id="HBH0003968.1"
                     /translation="MDEKITKNNYNVPFDYVRKKLKELDPHTISNLSNIPFNNDLNRF
                     TLNFFDRQYIIDYPSGEVWNSNGSLCNNFELKILIVRYLINAKGIPRTNKYVTFKEIP
                     GGNVYYPNFLNRTLYRLSEVFTSQIDKYKLVMEKIGAEKVNMGDLAYRFTYMGNTSMV
                     FILWFGDDEFPPNSNILFDSNIVYYFNAEDLAVVPDTAINAILNKINQL"
     gene            43944..44603
                     /gene="cprR"
                     /locus_tag="KR231_001587"
     CDS             43944..44603
                     /gene="cprR"
                     /locus_tag="KR231_001587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator CprR"
                     /protein_id="HBH0003969.1"
                     /translation="MSKILVVDDELDMLKLIENVLKRDGHEVKVISDVEKAMNMDFNY
                     FNLIILDVMMPKMDGFEVCKTIRNKVDCPILFLTAKNMESDIMYGLGIGADDYITKPF
                     GVGELRARITAHLRRESREKKNLLTISNVQFNFLGKEVSIDGKKINFTKSEYLICEFL
                     AKNKGQVFSKERIYESVYGFDGESDISTITEHIKNIRSKLKQYDIYTIETVWGIGYKW
                     V"
BASE COUNT        15646 a         6000 c         8109 g        14849 t
ORIGIN      
        1 acccgatagg atatacagac ctaagtagta gttactggca acagcactta atcggtgcag
       61 gacgagtaaa acaatagaaa ggacttgaaa aatatgttta agaagaataa gaaacagaca
      121 gaaaatgtca aagaaaaaaa ggtacgtact gtcaaggtag gcacacataa gaaaaccgtg
      181 attgcattgt gggtggtgct tattgcaagc gtgagctttg gagtatataa gaattttacc
      241 gctattgacc agcacacgac ccatgaaaaa gaagtgattg agcttcgctt gcaggacacc
      301 aacgggatag aaaatttcgt gaagaatttt gcaaagtcct attacacatg gagtaacagc
      361 aaagaagcga ttgacgcaag gacgcaggca atcagcggtt atctgacaaa ggaattgcag
      421 gacttgaata tggataccat tagaacggat ataccgacca gctctgccat tacagatgtg
      481 attgtatgga gcattgaaca gtctggaacg gacacttttt ccgctaccta cgaagtagat
      541 cagcagataa aagaggggga acagacaaca gcggttaagg caacctatac cgtaaaagtt
      601 catgtggacg ctggcgggaa tatggtaatt attcagaacc ctacccttgc accagcaatc
      661 gagaaatcag actatgaacc aaagacacca gaagcagacg caagtgtaga cgcggatacc
      721 ataaatgacg ctactgcatt tctggaaact ttctttaagc tatacccaac agccacagaa
      781 aaggagcttg cttactatgt gtctggaaat gtgcttgagt ctatcggcag ggactacctc
      841 tattctgaat tggtaaaccc tatctttacg gttgatgggg acaatgtgaa agtcaaggtt
      901 gccgtgaaat tcattgataa tcagacaaag gcaacacagg tatcgcagtt tgaattagtg
      961 ctacataagg agagcaattg gaagattata ggataattat tgaaagcgtg catttcttta
     1021 ggaatttgca cgcttttgtt aagagcatta ttctttatat ttatgaaaga catcttaaac
     1081 aaagtattaa tggcttcgca aaactttttt cttaatatat ttggattaga aaaagcgcat
     1141 cttaattgta gacttactat acatatgaat tatgccagtc aacgtattta aaatttatgt
     1201 tgttttattt tgttgtaaat cgcaagaata gataagagta atcaatggtg aaggggaatt
     1261 attaaaaata ctattggttt cttctgtccc gttccaattt gcgcattgta ttttttcata
     1321 aattacagag tggtcaatta tgtagttcag atattccata caaactaatt gtattgtttt
     1381 tacactcggt ttccatactg ccacttttgt cattctatca ctcataatac aaatattatt
     1441 atgagcaact tttctaagta gttcatttaa atttgataca tggtcaaggt gaaaaccaag
     1501 aagaagtttg tcagcactca tatgtgtcaa ggggaaatgc ctatttatgt gcgagagcgc
     1561 tatgagaaaa tgcttgccgt atccatccgt gctccaaatt tagaaggaat ggttgaaaac
     1621 tttgataagg atttatctcg ccctaacgag acggatttga tcgagctgaa aaatgccata
     1681 tcaaagtaaa ttgcaagaaa aaagcaagaa tataaatata gcattttcag aacactgtgt
     1741 taaaatgtta ttacttatac ttataaagga ggggatgttt cgtgtcaaaa gcaacactat
     1801 ttgatagtcg tatcaaaaaa tacgcatact gtagaacatc agaaatttat cgagacattg
     1861 gctcatctcc ggatggttta tccattgagc aaatcggttc aatgcgggag aaatacggag
     1921 cgaacagctt caatgggcgg aaaaatgata cgacgatgca acggttgaga cgggcattta
     1981 ttaacccgtt tcatgtgatt ctttttgttc tgggcattgt ttctcttgtt acggatgttt
     2041 tcgtagcatc caattttgcg agaaatgcta ctaccgccat tatcatcttt tccatgatcg
     2101 taattagtgg cgtaattcgt ctgattcagg agctgcgagc aaagagcgct gctgctcagc
     2161 ttgatcgcct agttcatgaa agcgtcacag tgaggcgtga tggaaagtta atagagattc
     2221 ctggcgaaga attagtggta ggggatattg tactattctc tgcaggtgat cgtgttccgg
     2281 cggatatcag attgacgaag attacggatc tctttatctc tcaggctgcg attactggcg
     2341 agagcgccat cattgaaaag agctgccgaa aactcagtta cggagagcag gatacactga
     2401 ctcagcttga aaacctcgct tttatggcaa ccacagtcat cagtggaaaa ggggaaggca
     2461 ttgtactggc agtaggcaaa gataccctgt atggaggatt taccaaaccg gattctgatg
     2521 ataaaaattc ctttaaaaaa ggagccgatt ccatcgcctg ggtgatgata cgttttatgg
     2581 cgatattagt tcccattgta tttatattac tggggattac tgatggaaaa tggatggaat
     2641 cttttgcttt cgccctgtca gttgctgtag gtctgatgcc ggaaatgctt cctatggtta
     2701 ttacagcctg ccttgccaaa ggaagtcttg ctatgagcaa aaagcagacc attatcaagg
     2761 atattaatgc catgcagagc tttggtagca tggatgtgct ttgtatggat aaaacaggaa
     2821 cacttaccaa tgaaagcatc ctgctggaat attatatgga tatttttggg aatgaaaatg
     2881 cagaggttct tgatcttgct tatctgaata gctgctatca ttctggtgtc tgcaatacca
     2941 ttgataatgc cattcttgcc tgcaatacca tgccagggcg ggaagcccat tacgcaaatc
     3001 ttctgacaaa attccaaaaa gctgatgaaa ttccctttga ctatgctcgt aagtttgtca
     3061 gtacacttgt acaggatagc aatgggaata gtcagcttat tatgaaaggt gatattgaac
     3121 atatattctc acgctgcaac catgtagaat atcgtggaaa acttctcccc atggggcagg
     3181 atgcgagaca gagtgtatct tctgtagtag gtgaaatgtt acaggacgga atgaaggtca
     3241 ttgcggtggc acgaaaaaat gtgggagcgc aaaagaaaat aactcctgat gacgaatggg
     3301 gcatgactct agttggctat ctatccttct ttgatgcacc aaagcagaca gcaaaggagt
     3361 ctgtaactgc actcaaaaga ttaaaagtta tccctaagat tctgacaggg gaccaggcag
     3421 cgattgctgt gtctgtttgc cgccgggtgg gtatttatac agagcgtatc ttaactggta
     3481 ctcaactgga tgaaatgaca gactgtgaac ttaaaaaggc tgtggaacat actcatgttt
     3541 ttgcagagct tactccggga cataaggtgc gtcttgtctc tgctatgcag gataatggtc
     3601 attccgtggg atttcttggt gatggagtca acgacattcc ggcactgaat gaagcaaatg
     3661 tgggaatctc tgtagatacg gcagtggacg cagcaaaaga tgctgccgat gtggttttgc
     3721 tgcaaaagga cttgaatgtt ttggagcaag gtgtaatgga ggggcgaaaa acttttacca
     3781 atatgctgaa atatattaaa atcaccgcta gctctaactt tggaaatatt ttttccatca
     3841 tttgtgccag tgccttttta ccgttcctgc ctatgacttc aattcagatt ctgcttttga
     3901 atctgctgta tgatacgttg tgtattgtgc ttccttggga caatgtagat gaggaagaga
     3961 tgctgtcccc aagagactgg tccggcaaaa cactgagaca gtttatgctg tctttcggac
     4021 cgatcagttc tctgtttgat attgtcacct tcctattttt gtattatttc ctatgtccga
     4081 tgctatgtgg aggggcaacc tatctgcagc ttacagatcc ttccctgcaa cttcagtatg
     4141 tagcactgtt tcagactgga tggtttttgg aatctatgtg gacacaggtt ttgattttac
     4201 attttctgcg aacttccaag attccttttt tccagagcag ggcatctgca ccggtcattt
     4261 ctataactct agtggggatt attgctttta cttcccttac atttgtcggc ggtgcgtcgt
     4321 tgtttggact gacgaaatta cctctttggt atttcgtatt tttactgctg gtggtatctc
     4381 tctatatgct gctgaattca gtagccaaat atttttataa gaaaaaatat caagagttga
     4441 tttaagagga ggcattcatg atgaaaaaga atattagtta tattccgatg gattcggctc
     4501 ttgaaatctg gctattagaa aaactactaa gagatccacc ggacagtgat tgtgcgaagg
     4561 atttactttc tggtattcag gagatgattc gtggagaggt atcttcgtta ttgttaggag
     4621 catcagaaga aagcgattgg ccagtgggta ctctgtcaga tagaatcctg gcaggggatc
     4681 tggaaattta tccaagaggc agaaaagtac tgataaaagg ttctgaagtc aacctgactc
     4741 caaaggaatt tgatattttg tactttcttg tccagaacaa aggtgaagtt tttacaaagg
     4801 aacagattta tcgtgccgta tgggaggaag attatattct ggataacagc aacattatgg
     4861 cttttatccg gaagttgcga aaaaagattg aacctgctcc ggattgtccc acatatattt
     4921 tgaccatctg gggtattgga tacaaattta atgatcagat atgacaaaga cggactaaga
     4981 ccattttcgg tttcagtccg tctattttct taccaaatcg caagaaaatc gcaagacttt
     5041 agccatagga ttgtatttgg attttttata tactgttagt agttaaaggg aggtgtttca
     5101 tatgttttac acagatttta ttttgagaat tgccctctcc ttaacacttg gatttcttat
     5161 tggattagaa cggcaattga ctggtcatcc tgcaggtatt cgtatcaatg tgttaatctg
     5221 catgggtaca agtttcttta ccttgtttcc tatgctctac ggttcggatc aggtattccg
     5281 tgtcggaagc agtattatat ccggtgttgg ttttttatgc agtggtgtta ttttcaagga
     5341 cagagggaca gtacgtggaa tgaataccgc tgccacctta tggtgtactg cagcgattgg
     5401 aattcttgca agtacgggaa tgtatgcaat ggcgatcacc gccgctacta ttttaattgg
     5461 ttccaacctg attctacgtc cctttgcaag aaagtttcac ccaattactt ccagtgatga
     5521 atctgaaaag cagtatcgta tttcggttac atgtcaggaa aaggcagagc aggatatacg
     5581 cttattgctg attaacagca attcctgtaa gacgctcttt ttgaacaatc tggaaagcgg
     5641 tgatgtggtt ggtgacaagg ttgagattgt cgcagaatac tgttctgtcg gaaaatccaa
     5701 aaacaatatt ttagaaggaa tcgttgggca ggtattggta attccggaag tgattagtgc
     5761 tggttgggag gtgttgtgag tgaggagaga aatcgaagat ttgaaacgag caattctttt
     5821 tgctttctac cctgtattta caatcttatg tagctatttg ggttggaatt tctttgaaca
     5881 aagaatggta atctttaaga tatggtatca ggtgagtatt gtgatctggt ttattcttgc
     5941 tgttactatt attgtgctct tcattaaact tctgaagctg acaaaactaa gaaacaggtt
     6001 taagcattga aaggaggaac aaacgatgga ttttacatgt atcttttttg gaattttatt
     6061 tactcttgca ggcttttggt tggcctttgg aaaaggatat cgtcatcttt ccctgtggaa
     6121 aaatatgccg caggaggaga aagataaaat taatattgtc ccgctttgtc gtaatgttgg
     6181 agaaatgatt gcgttaaatg ggattatatt cttaatgaaa ggatttttgc cgggattttc
     6241 aaaccactgg tttgtatttg caataatcgc atggctgatt gttgccggct ttgatgtctg
     6301 gtatatcgaa aaaagtgtcc gctatcgcaa ccaataatcc acattgaggt ttcacataga
     6361 tattttttta agattgtgag gtgaaagaca tggactctga tgtcagtcca cgaaggcaga
     6421 gaatattata tgagaatttg gagattccgt gtcgctcata taatattcct tgcccctatg
     6481 aaaattcaag gaggtaagac caatgaacaa aaaagaaaat cgtatggcta ttcgtcagac
     6541 tgtagaaaaa gcagtcatcc gtgacgaaca gaaccgccgc attcaatttg cggcaaccaa
     6601 tcctattaaa gaagttttaa aaaaacttca taccacactt cgtggcttag aagtagatga
     6661 agtatccgta agtcgtgcta aatatggtac caataaagtc actcatgaaa aaaagaaatc
     6721 tctggcaaaa cgactggttg gcgcatttat caatccattt accgccattt tattttgtct
     6781 ggctttagta tccacaatta cagatatgat ttttccgtat ttttctctgt ttggcagtgt
     6841 gccagaggac tttgattccc tgactgttgt aatcatttta acaatggtat tcatttccgg
     6901 tacgcttcgt tttgtacagg aatccagaag cggaaatgca gcagagaaat tgttagccat
     6961 gattacgacc acttgtacag ttactcgtag aaactatgaa aaaaaagaac ttcctatgga
     7021 tgatttggtg gtgggagata ttgtgcatct ttctgctgga gatatgattc cggcggatgt
     7081 tcgtattttg gatgcgaagg atttgtttgt cagtcaggca agtcttactg gtgagagtga
     7141 acctattgaa aaaacaccca atgtaagtgc tcagaaagaa agcgtgactg attacacaaa
     7201 cattgctttt atggggagta atgtaatttc tggtagcgca acagctgttg ttgtttgtgt
     7261 tggcgatcat actctgtttg gctctatggc gtccgcagtt gctggagaag cggttgaaac
     7321 aagctttacc aagggtgtca atgccgtttc ttgggtattg attcgtttta tgctcattat
     7381 ggttccgctg gtgttctttg tcaatggtat caccaagggc gattggttgg cggccttctt
     7441 attcggcgtt tctattgctg ttggtttgac accagaaatg ttgccgatga ttgtaacaac
     7501 ctgtcttgcg aaaggcgctg tttccatgag caagaagcag acaatcgtta aaaacctcaa
     7561 ttccattcag aacttcggtg ctattgatat tctctgtact gacaagactg gcacgctgac
     7621 ccaggataag gttgtgctgg aataccatct gaatgtaaat ggcgaggacg atacgcgagt
     7681 actgcgtcac gcttacctca atagttactt ccagactggc tataaaaacc tgatggattt
     7741 ggcaattatc cataagacgg aggaagagga agccgcagat tcgcgtctca ttgacctgtc
     7801 tgaaaactat gtgaaagtag atgagattcc ttttgacttc acacgtcgtc gtctgactac
     7861 agtggtacag gataataagg gtaagaccca gatggtaaca aaaggtgctg tggaagaaat
     7921 gctctctatt tgtgcgtttg cagagtgtaa tggaggagtg cagcctctga ctgatgacgt
     7981 tcgttacaga attctggaga cagtggacaa tcttaacgat aagggattcc gcgtactagc
     8041 tattgcacag aagagtaatc cttccccaat cggcgcattt ggtgttaaag atgagtgtga
     8101 tatggtactg attggatatc tggcattcct tgatcctcca aaagaatcta ctgcggatgc
     8161 tattaaagct ctgaaagacc atggtgttat aaccaaaatt ttgacaggtg acaacgacaa
     8221 agtgactcga actatctgca agcaggtggg attagaggtt cgcaatatgc ttctcggttc
     8281 tgatttggaa caaatgggcg atgcagagct tgcaagagtg gcagagtcta cagatgtatt
     8341 tgcaaagcta acccctgatc agaaagcccg tgtggtttct gttctccgtg aaaatggtca
     8401 tacggtcggt ttcatgggtg acggtattaa tgatgctgca gctatgaaag ccgccgatat
     8461 tggtatttcg gtggataccg ccgtggacgt ggcaaaagaa tctgctgaca ttattctatt
     8521 ggaaaaagat ctgatggttt tggaacaggg tattattgag ggacgaaaga catatgccaa
     8581 catgatcaag tacattaaaa tgactgcttc atccaacttc ggcaatatgt tctcagtgct
     8641 tgctgcatct gctttgctac ctttcttacc aatgatgagt gttcatctta tatttctaaa
     8701 cttaatttat gatttatcct gtactgcaat tccttgggat aatgtggatg aggagtttat
     8761 taccaaacct cgtaaatggg acgcttccag tgttggaagt tttatgatct ggattggacc
     8821 aaccagttct atctttgatt ttacaaccta tatttttatg tactttgtat tttgtccatt
     8881 gttcgtatcg aatggtgtat tatttaatga tttgcctgct catttcagcg gtgcagaact
     8941 ggcaatgctt caggcacagt atatcgggat gttccaagca gggtggttcg tggaatctat
     9001 gtggagccag acattagtca ttcacatgat tcgtactcca aagctacctt ttgttcagag
     9061 tcgtgcatca gctccggtga ctttgctaac aatgactgga attatagttc tgaccattat
     9121 tccgtttact gtgtttggaa ctatgcttgg atttgttgca ttgcctgcag catactttgc
     9181 ttatctgatt ccatgtattc tgctgtatat gactttggca acaagtttaa aaaaagccta
     9241 tgtccgtcat ttcggagaac tgctttaagg aggtggaatg atgaactgga aagaactttg
     9301 gatgaccctt tttggaacta ccgaatggct tggtcttaat atcggctttt gggtggctat
     9361 ggcagttgtg ttgctgattg ttattgtaat gaatgtagta ttttggtcca tgaaaccaaa
     9421 aaaagacaca aaagagtctt ataaataaga tatcagtatg aatgaatcaa gggagatgca
     9481 cagtttttta ttgtggaatc tccctatcat atcaaggcgc attcaattgt ggcaatttag
     9541 tagtaaagta tgtgtttttt tatcattgaa ttacctataa atgctgtata taagtggata
     9601 attgtaattt cgatataaaa attatggtac ttaaaagaaa tttcgttttt tattgtttgt
     9661 ttacgcgtct ataacgaaat cgtgaaataa tattcaaagg tagattttat tatggaatgt
     9721 atgtctgtag aagaagcttc gataaaatga ggagatatct gaaagaagga taaaaaaatt
     9781 atgtaatgga aacagaatcc caaatctatt gtaacaacaa tgacaggtaa tgaatggtta
     9841 cgtagattga taattcctat tcaaattatt atctatctta tattgagtgg tgttttgtaa
     9901 ttacattttt atacaaaaag aatatgttga acgcacaatg ataaatattt tgtattcccc
     9961 aactaataga ataaagtttt tgcttggaaa gtatgttata taggcattat ggtttgtaat
    10021 gatcacgttg acagattata ccgctatata tgaagtcaaa gaacttaaat catttacaag
    10081 tgagataatc tatctaagtc taaaaaactg gatttctcaa tctattgtca atgagtccat
    10141 tacttattat ttgtgttttg caaagaaatg ttttctactc tagtttactt tttagttact
    10201 aaatatcggg aattggtttt gttggactat attgatctga aagtatacaa aatattattc
    10261 cgtggtctgc tgtaacccct ataagtttat tagatgcaca aggattgcta ccttatattt
    10321 caattctact ttgttatttt gcaagactga ttataaatac atactgcttt agagggttta
    10381 gtttagttct ttttgaactt ttgaataaga cgacggttat atagccgccg ttttattttt
    10441 gcctaacgtt ggacaaatta ctggatggtc ttgttttatc ggctctaggg gtagccgtat
    10501 gaaacactta catattcaac aactttcgac catcggtagt tcattaaaaa aacatttaaa
    10561 ttctacggaa cataatgctc ctatatgtgg ttttttacag catataacag gaataatttg
    10621 tttagcacaa gatcagtacg tctgtattgc ccttgtgctt ttttactgca taaaactttt
    10681 tcaaaaaatt tttgcggttg ggtatcaaat cccacctttc atggtgagtg ttagtgcgaa
    10741 aagaggtaga agtcttttcg ctttagcaac tttcgctgga aagggggtga gattatgaaa
    10801 ccatcttctt tcgagggcgc tatcagactt caatttgatt gtctagctcg caaggttgta
    10861 ggacgaactg taaagaacta tgaccgagag cttggcagac gtgcaagacg tgaaacgccg
    10921 ttctgtgatt tatctgaaat ggagttaaac cagatcggtg ccatggacga atattgcgtt
    10981 gagtttacgt catttgatgt atttggttca gaagtccata tctatgatga acgcttatgt
    11041 gaagctatca aagaattaac agaaagccga cgtaacattc tgcttatgtc ctactttctt
    11101 gaaatgaccg acgctgaaat tgcagaggtt atggaaatgg aacgattttc cgtatgtaga
    11161 aacaggctgc acacattaaa gcttattaag gatatgtacg aggaggaata aaaacatgat
    11221 gaagtctaca aaaaagtgtc catcattctc gaccatcagt tctgcagctg acggtaacga
    11281 ggtggcaatt gaaaagattt tgaaccatta tgacgcttac atatcaaaag ccagcctacg
    11341 cccgttctat gacgaacacg ggaatatgta tatcgtgctt gatatggaac tgaaaggcag
    11401 gatacgggca gcgttgatta aagtaatctt agggtttgaa gtcaaagtga agtaaatata
    11461 acagagagta tctaccacct cattttaact cttttccgtt ctttgacaag tgaatacagt
    11521 aatcagatac gtttgatata cgacgagcca gcggactgga acgccacgac cactgaaatg
    11581 gggaaagcag cgagcgatta tgccagtgaa ccgcaagcga tctttggaaa ggttgctgcc
    11641 atgactcgta tatctgaata atgatacacc cgtatgacac ggttcaccca tcagaatggg
    11701 aatggtgaaa gtccagtgga gctgccgaag ccgtctgatt acttccataa ataaaaaagc
    11761 aaggagggtt ttaatgaata atataattag gtatagtatg caaattgcta tgttaaaaca
    11821 actgcttgcc cgtaaactga tttctgaaaa agaatacact cttgtaaaac aaaggctgat
    11881 gaaagactat aaggtgcttt ctgacataac tgcttgaatt gtgtttttta aagtagtaca
    11941 ataacaatat gaaaggaaca caaaataagg aggtgtacta tgcaggaagt tgaagtaata
    12001 aaagcaaaaa atgttttggc aagacaagcc cgtggaaaag ccattgagcg tttgcgtgta
    12061 gctgcatatt gccgtgtaag tacagatagc gaagatcagt taaacagtta taaatcacaa
    12121 gttcagtatt atactgacat gattaagaaa aacaaggaat gggtgttagc tgacatttat
    12181 gctgatgaag caattacggg gacacaagta acaaaacgag aagattttca gcgtatgata
    12241 aatgactgta tgaatggtga aattgacatg gtatttacaa aatccatatc aagatttgcc
    12301 agaaatactt tagacacatt gaaatatgtt cgtatgctaa aagagagaaa tatcgccgtt
    12361 tattttgaag atgaaaaaat caatacactt acaatggatg gagagttatt gcttgttgtt
    12421 cttagttctg ttgcacagca ggaagtcgag aacatttcag ccaatgtaaa aaaagggttg
    12481 aaaatgaaaa tgaagcgcgg cgagctggta ggttttcaag gttgtattgg atatgattat
    12541 cacccagagg ataagacaat aactgtaaat caagaagaag cagagattgt cagatatatt
    12601 ttcaaccgtt atgttgatgg tgctggtggt tctgttattg gacaggagct tgaaagtcta
    12661 ggttataaaa cgaagtatgg gagttccaca tgggcaccat ctacggttat tggaattatt
    12721 aagaatgaga aatacaaggg tgatatactc ttaggcaaaa cttttactgt tgatccgatt
    12781 tccaaacgtc gccttgaaaa catgggtgaa gaagataaat tttatatgaa agatcaccat
    12841 gagccgatta ttagtgaaga agtttttgaa aaagcacagg aaattcttaa tcggagaaat
    12901 aagaaccgaa caacggtagg cagcggtaag cgtgagaagt atagcaggaa atacgcattt
    12961 agctgtatgc tagaatgtgg cttttgtggt ggtactttaa caagacgtaa ttggcacagt
    13021 ggctcaaaat acagcaaggt tatatggcaa tgtgtaacgg ctacgaagaa aggaaagaaa
    13081 ttttgtaaac atagcaaagg tattccagaa acagctattg aagaagcatt tgtagaaagt
    13141 tatcgtttat tatgtgatga taataaagat gttctggaag aatttttgca gagaatggac
    13201 gatactctta gtagtagtgt ggtgtcaaaa caacttgcaa aagcggaaaa ggagatagac
    13261 gcattagaga agaaaaaaag taaacttgtg gatatgcgtc tggaagaaat tattgataag
    13321 gaaacctacg aaagtaaata tgctgattta gtaagtaaac aagaacagct tgttgaagaa
    13381 agacaaaagt tacaagaaac ttctgataat gagaaagaca taaaaaaacg tttgaaagag
    13441 tttaagaaaa ctctggaaca gaatgaggtt cttgataaat ttgaccgcta tgtgtttgaa
    13501 agcattgttg aaaaagtaat tgtaggtgga cttgatgaaa acggaaatgt tgaccctgca
    13561 cagttgacct ttgtttataa aacaggcttg aagaatagcg tagatggtgc taaatttaaa
    13621 acacaaagga aaaatgcaag aggacggcat aggactaatg aattgtgttc acatgacagc
    13681 aacgaggttg ataaaatgtg ttccgatagt agtaacgaca catgtggaaa ctgtagctaa
    13741 gataatcaaa caatagtaat gtttatatag attatatact aataatatat tgtatttgcc
    13801 accgatttgc cactgtaaag cgatttcggt ggcaaattta gtctacaatg ttatcaaaaa
    13861 tctctaaagt tttattttta attctataaa acttattata attgtaattt taaaagaaat
    13921 agtcaatcta cagtagccag attttataca actcattttt ttcatagagt aatttacata
    13981 atctatagtt gaatattatt taatattttt ataattcatt agcaaatata ggcattacaa
    14041 atgttgataa acatgtgaaa gcacatatcc acttataatt atttttttta aaaccataaa
    14101 atcacctctt catttgttgt atgtttttat aacaaatgaa gaggtgattt ccagacaatt
    14161 taaaaggttt ttgtatattg actaaaattt atttttatta tttataattc ttaataatac
    14221 atatgtacct actgattcca tattaaactg tataattttt gttcatcttt ttttataatt
    14281 aaaactacgt agttctcata atttctctta tatatatact tatcatcttt tttaacttct
    14341 aacttatatt ttttaaaatc ttcttcaatt ttatttttat tacttttatt aatgttaaca
    14401 gaatctcttt taaatttatc aatatatttt tctatttcat taatattatc tttgcttaca
    14461 actataccac cttttaaatt aaaaactttt ttgaaatttt tttcagaaaa tccttgaata
    14521 aaataacttt gtccatctcc attaatacta tcttgagtat caaatacttc aatttctttg
    14581 ttaggtattg gtatatcaaa attccaagat tcctttagca ttgaaatatt agctgttttt
    14641 cctaaaaaaa gattatatag gatacttcct aataacaaaa cacctattaa tagtagtgtg
    14701 attaatacaa tttttctctt tttcattttt cgttcacaac cttttgaaaa aacatgattt
    14761 aattcatcat ttgaaggcat gtcttcaaga ataatttttg ttgtgatagg aatgctttct
    14821 tgaaacatat catttgtaat atcaaaatct tttctttgat tactcaatat ccatttcttc
    14881 taatatttct tttgattttt tctagtacat tgaatactct tatatacatt ctcctctttt
    14941 aaaattaaaa gttataaaag aataagttat ataaaaaatt attatatttt ttaatatagc
    15001 ttatttgcaa atttataatt ttgttaatct aatccttcaa actaaaaaat catttatatt
    15061 tacagaattt cattttaaga gatgtttatt ttcacataga taagagaatt taagttctca
    15121 tatttattat ttgatacaaa tttacatctt tattatatgt attttaaata aaaaataaaa
    15181 ttatgaatac tagaaatcta tcttaattag ctttctaaca taaggctatt taaagtagat
    15241 aaaactaaaa agggttctct agaaaaccaa atctatttaa ttatacttac ttactaatac
    15301 catcacttga tgcaaacaag attctaccac attttctccg tactctagta taaaatcatc
    15361 tagttgtgta tctataaaat cacaataatc atatgaacta ccaatataag cagtcaacat
    15421 atgtgtacat ctatccattt tatctctaaa catatatatt attatccccc taaaaaactt
    15481 tcataaaaac aaaaagaata tctctttttg gcaactggct gacataactc atagtttatt
    15541 ttataagcgt tagtccctat agctttgcgt cactaaattt ctctagtttt gccgatttag
    15601 ttttattcta caattacaat aatacaatag aattgcttat tattcaatat acttatttga
    15661 aaattaaata aatttacaaa tatgaacgtt attttatatc aaaaaaaata gactatgcat
    15721 gtagaatata tggaaaaact tgattgtagg ttttgtatga aaagacagtt gttattaatt
    15781 taagtgagat aaattgagca acaggcataa aatgagaaaa caaataatag cagttaattt
    15841 ttattattaa tactaggtga acattaaatt tcaaaatacc actagatttt atagaataag
    15901 aaaatgagac aaacataaat atatgaatat attaaattat acttgaacat acttatattt
    15961 tatgataaaa tttcaataat aattattagt gaaggagtgt cttgcctgat gtcagagtta
    16021 tatataatgg taaccaacaa ataaatagtt ggagacgcat atgggttctg tttaatcaga
    16081 gtttttaagt gtatttttga tacatttgat tgttgtgtct tactctgcct ttatagataa
    16141 ctaacattag acaacaaata ataatattac atattacttt gttaaattgt ggtgtagtgg
    16201 gctttaatct gctacacttt tattaatttt acacagtatt attttgaata taattatgtt
    16261 gaaatagaag atactaaatt ttctagtcca caggggtttt ctgtttttgt gtaggtaaat
    16321 atgtatacca cataaaaagg cagatataaa tacctgtgga ctttttttgt agaaaataca
    16381 cgatacggag gaaataaaaa tgaattataa aaatagaaaa cgagcttatt atcaggaaaa
    16441 ttcctgtatg gataacttta tttgcaaaaa ttgtggttgc cttgtagttc ctgaaggagc
    16501 tggtacacaa catagaaatc attgtccaca ttgtttacat agtcttcatg tagatatcat
    16561 tcctggtgac cgtgctgcag attgtgatgc taatatggaa cctattggag tgtgggtgag
    16621 aaaaaatggt gagtgggcaa ttattcatcg ttgtacacgc tgtggacatc ttagttctaa
    16681 tcgtattgca gctgatgata attcagtgaa attaatgtca attgcattaa aaccactggc
    16741 acagccccct ttcccactag aaagaatcat tgaaaagttg gaaaaggagg aaacagaatg
    16801 aatggtatga aacaaatcaa tttacaagac tatggtctaa atagaaattt tattactcaa
    16861 agtatggaat atcatgattt ataccttgct cggattatct cgcaggaaaa gaacttttat
    16921 caagctgtat gtgtaaatgg tgtactgttt gcagaggttt caggaaagct gcgttttgag
    16981 gctactatac aatctgattt tcccacagtt ggtgatttcg ttatgttgga tcgttgcaat
    17041 aataaaaatg gtaatgctat tattcatcat gtgcttcata gaaaaagctt gtttgtgcgt
    17101 aaggctgctg gaaaggtaaa tgaggagcag gtggttgcag ctaatattga cattgttttt
    17161 ttgtgcatgt cactgaataa ggattttaac attcatagat tggagaggta tctgtcttta
    17221 acatgggaaa gtggagctat cccagtagta gtacttacta aatcagactt atgtgacaat
    17281 gtgcatcgta aattacaagt agttaattct atagccttgg gtgtagatgt agttgttacc
    17341 tcatctatag agccagatgg ttataaacag atttctaagt atattaaacc aggctgtact
    17401 gttgccttac ttggttcttc aggagttgga aaatcttcat taattaattg tctgatgggt
    17461 ggagaatttt taaatacaaa ggaaattcgc atagatgatg ataaaggaag acatgccacg
    17521 actagacgag agctattttt aatttcaggt ggtggtattg ttattgacac accaggtatg
    17581 agagagttgg gaatgtggga tgtttcagaa ggtttagata aaagttttgc agatatagaa
    17641 gcttatttcg gaaaatgtca ttttcgtaat tgtactcaca cctcagaacc aggctgtgct
    17701 atctgggaag ctattgctca tcaagaactt tcgcctaaaa gatgggaatc ctatcgtagg
    17761 cttaaaactg aagcagtatt tgcagacaat aaaagcgaat acttagcaaa aaaagaaaag
    17821 aaatttaaaa atatctcaaa aataaataag aagattagaa gataagtgta gtttttttgt
    17881 tcattctatg agtctatata ctattaatat attaaatttg ccatcaattt gttactttaa
    17941 tgtgattttg atggcaaatt tggtttgtgg tattatttaa agcaatttat taattttttt
    18001 aataaagttt gattttttat atgatgatat atacatgtga taatgtatac atatttgtta
    18061 cgataggctc ctttataaag aggtcttatg taagataaga aaaggcatat ttatactaat
    18121 acataataga gtatatgctt atgtatgata gagatgtttc ttaagagcaa aactgcaata
    18181 ttgctaattt ataaagtaaa aatatatgaa ttataaaata caaataatat atttataaaa
    18241 attattgttt taatttataa taaaaatttt ttgttgaaaa taatgctcga acctataaaa
    18301 ctattaacta atatttgtaa atgtatactt ttgatgataa aatataatta agttaagttg
    18361 gtttttataa acataaattt attttaagga ggtgaaataa atgaaaatat ctagtcaata
    18421 tagaagtcaa tattcattta gatatgaaag taatataaat aatacaagaa taaatgaaag
    18481 tatggttaag aaaaatgaaa ctgtaggaaa agacacttat ttatctaata ttatgaaaca
    18541 aaagcaagaa cttaatgata gaattagaga tttaaaatat agacaagagg tttatactaa
    18601 aaaaataaat gacgcaatta agaacttatg taaatcagaa ataagagaaa caactaataa
    18661 tttttctaat atagaaatag gtattaaaaa tagcattata gaagagaaaa ataaaagtac
    18721 aatgttagat gaaaattcaa cttatctaaa tacaaatgat gaaaaagaat ctttaatcac
    18781 taaagagtct aatgaaaaaa ttgaagaaga aatattaaat gatgaaaaat tagaagagtt
    18841 agaacaaaaa aaggattata aagaggattc taataaaaaa gagaaagtat ctgaggactt
    18901 atctttagta ggtaaaactc gtgaagagct tgaaaatatg cttaaaaatt ttataaattt
    18961 aacacaagaa gaaataatga aacttgagtc gagaatagaa aagttagata aaaatgctga
    19021 agaatacaaa caaaattcaa agactaatat atttgataaa acagatgaac aaaaaaaaca
    19081 tataaatgta ctgatttaaa caatatgttt taaaaaaata agtttattat ataatgaaaa
    19141 tataaaggta caatttcaat acacttctat taaaccaata atttatgaat cagatttaat
    19201 ttcaatttac taataaccat atatttatga gttaataatt ttatgtttta aaaagaatta
    19261 aataaggggg agtagtatga agaagaatat attaactact atgattacca tgattattat
    19321 attgatgatg agtatgacag taatggcaga gccatatcaa gaagatgaaa catctagctt
    19381 gaaaaaacag agtgcaaatg aacgtaatca gactaatata ggcacaatgg atggcagagt
    19441 gcaaacaaat gcaataagta aaggtgctaa ttatgaccct aaatatcctc ttaaaggaat
    19501 gttaacacaa cttggtctta atacaacagg taaagaggga tgggatttac tctatggagg
    19561 aaatcccaat ggagttgagc ttcgagcaga tggtaaatat tattatataa ataagggtat
    19621 ggaagggcta ggattttatg cggcagcatt gtcaggtggc tcatatcaga gaataggctt
    19681 tggaaaactt gaccctatag aagtaatagc tgatggaaat tggatttctt acaaacaagc
    19741 tcaagataca cttacagtaa tcaggaattt tttaaatagc tttgactgga gaaatgcatc
    19801 tgagatggaa agagctaata gagctgcaaa attggtaacc gaagcaaaat atgcagactc
    19861 taaatattgt aacatagtct atggtaatct ggttgataaa cgtggtgtat gtggaagttt
    19921 tgcaagtagc tttcatttat taacaaggtt aatgggaatg gattcactat ctatattaaa
    19981 tccatcatta aatcatgctt ggaactatat acaaattgat gggaaatggt ataggtttga
    20041 tgggtctgaa atatcagctt ttggtggatc attagacttt gattaccgta aattaaagga
    20101 tgcaacaaga gagatgacta cttactatga tgctaaggca ttgtctatat taggatttaa
    20161 tcaataaaaa tagggggagg cttcttatag agcctttttt tattgatttg aaatttaata
    20221 aggaatttta tatgaaaatt taatcaataa aagcaaaaaa ggctctttat aaagcctttc
    20281 taagtgtttt tttaagtaaa attttttata tcaacatcag ttttaatcaa aacatataac
    20341 attttggact tacttttaaa aataaaatta ttaaaatata atattaatca tgtttttagt
    20401 ttattatatt ctataatagt ggtcatgttg actattgtag ttttattaag aatagttggt
    20461 ttatataaat atatgcaaag atagcttgtt gtttacttta cttattagta tataggacaa
    20521 gatactctaa taaatttgcc tattttaata tcttttgtac taaaaccaac taaagtttcc
    20581 tttattattt cgttttgaat aatacaaagc ataatccgat tgtttgtata aagactggaa
    20641 agtatcagag ttattttcta atttagatat acctatagaa caagaattac tctctaggca
    20701 taattctaaa accttctttg ccttattttc aacattctct tttgattgat tactatattc
    20761 aaaaacagca aattcatctc caccaagtct tccaataata gcatcattta cgaatacttt
    20821 agtcaaaata tttgaaaaat gtattagtat ttcatctcct cgaacatgac caaagatatc
    20881 atttacctgt ttaaaattat ctaaatcaaa gatgtaaaag tatccatgtg aaacagtttt
    20941 aagcatttct tttatgtgta cttcaaaaaa atgtctattg tatagtccag tcataaggtc
    21001 tttttctgat tttagtttaa attcatttgc cattgctagt gcttcttgtg ctttttcagt
    21061 tattgtttta gggtaatact catctttcat ttggtcaaag tttggaatag aatggtgaac
    21121 atggataagt ttaatcatat catctgtaac tctgtatacc atagtaaatc gagtatccat
    21181 ttctacatag atatcttttt ctaggtaatc tttttctatt acccaaagag taccatatac
    21241 tataaaagct tcgtctgtaa ctttggtaca tgaataccac tcatctataa tctcaaagtc
    21301 tatttgctct gattctgttt ggtctttttc aagacctata ataaattctt ctaatgtttc
    21361 gtaaaattca tgttttcctg ttccaattaa tgcaaggttg tcatctaata aggaaataat
    21421 aaatttaagg ttttcttctt ctggatttaa aatataaata tgccaaattt tttttgataa
    21481 atctcttaat tgtttttgta ttgtattatt ttccatagat taccccctta agatttacag
    21541 tttatatttt aatgtattat aagttgaact cttattacaa tattattata atatagaact
    21601 aaagaaatta catcctgtat aagtaaaagt atatctttta taataaaaat attacagtaa
    21661 aataaccagt tttaatatac gtattatatt tttaatttat aaacgaatat tataaatgaa
    21721 atttaaattc aaccctgaag aaataagcta aatgtattag tatataaatc catacttgaa
    21781 cataaataac ctttatgata tgatatcaat aataatatta tgagaggagt gccttgatgt
    21841 cggagttata taatggtaac caacaattaa atagttggag acacatatat tctgtataat
    21901 cagaaatttc aagtgtattt ttaatacatt taatttttgt gtcttattct gcctttatag
    21961 ataactgaca tatgacaaca aatagtattt aaaatatata ttactttgtt aaattatggt
    22021 gtagtaggct ttaatctgct acacttttat taattttgta tagtattatt ttgataacta
    22081 ttttgaaata gagagcatta atttttctag tccacaggag ttttctgttt ttgtgctgtt
    22141 aaatataagc acagagaaag gcagatatat acctgtggac tttttttata taaattatga
    22201 aatatggagg tagttaaaat gagtataatt gaacttaatg aactgactaa atcttataga
    22261 agatttgaga aaaaggcagg atttatgggg agtgtaaagt ctttatttaa taggaaatat
    22321 acagaaaaaa cagctatatc gtcatttgat ttaaagatag aagaaggaga atttgttgga
    22381 ttaataggtc aaaatggagc tggcaaaact actcttatta agatgttaac tggtattatt
    22441 gcaccgtctt ctggagaaat atctgtaatg ggttattacc ctaacaaatt agaaaataat
    22501 tttaaaaaac aatatgctgt tgttatgggc caaaaaagtc aactattctt tgaattgaca
    22561 ccagcagata cgtttctttt atttaaagaa ttatatgata tatctaatga agaatataag
    22621 aaaaacttgg attactttat cgaattattt gaggtatctg actatttaaa tgttcaagtt
    22681 aggacgcttt ctttaggaga aagaatgaaa atggaactaa tagtagccct tctacataat
    22741 ccaaaaatat tatttttgga tgaaccaact ataggcttag atgctatagc ccaaaaacaa
    22801 attaggtatt tcctaaaaga agtaaatgaa acaaaaggaa ctactattat acttacttct
    22861 cattacatgg aagatattaa gagtctctgt agtagaagta ttgttgtaga aaatagccgt
    22921 aaaatatatg atggttctac agagaaacta tttaattatt ttcaaaaata taaaaaaata
    22981 acagttagtt tttccaatga aactaacatt gtatttccaa aagattgtaa agttgttgaa
    23041 caaacaaatc ataagatatc agtaattgtg ccaaaagaaa gaggaaatga aacgattaaa
    23101 tggatttttg ataaatatga tgttaaagat gtaatgattg aagaagaaga tataggtagt
    23161 attgtagaga ggatatataa gaaaggaagt gatgagtatt atgagcaact ataatgaagc
    23221 aagttcaaat gattcaatgt tttataaatt taaacagagt attagaaggt attatgaagt
    23281 agccaaaatt aactttaaag tgcaacttat ctggagattt gatgtggtgg ttaatatggt
    23341 gtttacgatt gtaaaaattt tatttgctta tattttatgg aaagcaattt ttggtgaaaa
    23401 taaaatagtc tctggtttta catttaactc tatgttatct tactatataa taagctcatt
    23461 tttagcaggt attgatatgt caaagagtac cagtgaagag atatgtaatc gtgtaaaatt
    23521 gggcaccttt tcaaagtaca tgattattcc aattaatgtt caaaattatt ttattgctaa
    23581 aaattttgga atgacatgtt tttattttgt atttaatatg atttctgcat ttgtatggat
    23641 ttttatattt aaaatagatt ttgcctttac atcaaatcca gttcaaatat taatttcaat
    23701 tttgatgatt tttctagggt ttatttttat gatgaaactc cacttcttta ttgggatttt
    23761 gtcatttaaa tttcttgaga ttagtttttt aaaaatgata attgaaaata ttgttgaatt
    23821 tattacagga acaatgatac cacttgtact cttaccagaa actatagtaa cagttatgaa
    23881 ggtatttcca ttttattata caacatattt gccatctatg ttactaatag gtagaaacag
    23941 caatgaggca atacaaggat taattattct agcattatgg gttttatttt tttctgtagt
    24001 aaataaagtt atgtataaaa gaatgagaac attatttgat ggggtgggta tatgatgaaa
    24061 aaaaatttga aaataatatt tatgttatta aaaatgaaat tatcaaagat gatggtattt
    24121 agattcgatt tttttggagc attttttgta gatagttcat tatttatatt acaacttcta
    24181 atgtttaata gtatatattc tcatgtagac tcaatagggg gatggcaaca aggagagatg
    24241 ttaatattta taggaacttt ctcattaata aatgcgataa atatgacgat tttctttttt
    24301 ggtatttatg atattccacg aaaaatccaa gaaggagaat tagactacta tattacaaaa
    24361 ccattagacc cactatttag gttaacattt gaaaatatta atattggttc atcaccatta
    24421 attctagcaa gtatacttat tgttttatat ggaatatctg agttaaactc agagataact
    24481 ttagttatga taataatata tattttcatg gtgttattga tgacattact tttttatgat
    24541 gtatgtatca tacttagaac agtttcattt tttgttatat catcttctgc gataatgaga
    24601 ttagaagata atttattgcc aatgaatatg aaaattcctg gtgtaatata tgaaggtatt
    24661 tttaaagtat tattctattt aatcttacca tatggaatta tgtcgacaat tccgactcaa
    24721 attttggctg ggacaataac aattaatgga ttaatatact caattttaat tgtatttttg
    24781 tttacattgt ttatgtggag attttggaag ttaggtatga gacattataa aagtgcaagt
    24841 agttaataaa ttagtaaaaa tagacaatgt ataactatat ataaatacgt ttcatatgac
    24901 actaaactat gtgaacaagt atttgcgcta aaggcactga aagctataaa atgattaaag
    24961 taaggattta aaagtttctt tagtagaaat ataattgtgt aaaaaagcaa gattaattaa
    25021 aactatatcc aaataattag atataattct tatgcagaaa ggaggtctgt aaatgtctaa
    25081 ttgtttggaa tatattttaa aaataattaa tgtacagaaa aataaacaaa atgagtgatg
    25141 tatattattc agaaaatcat gaacaagata atctttatga gcaagataat ttactggcac
    25201 aaagatttaa tttatttact ctattgaagt ttgcatttcc tactattttt atgatgattt
    25261 ttatggggtt gtatacaatc gtagatacta tatttgtatc aagatttatt aatacaaatg
    25321 ctctatcagc aattaatatt gtatgtccaa ttattaatct tatagttgga attggaacta
    25381 tgcttgccac tggaggaagt gctattgtag cacgtaagat gggaaatggt gatattgagg
    25441 gagcaaataa agctttttct ttaatcgtat tatcaggagt tgtaattggg gtaataatta
    25501 ctggtatagg tattgtattt atggattata tcattatatg gttaggagca agtgaagttt
    25561 taattaaata ttgtcgttca tatcttttta ttatcttggt ttttgcttct gcaaatatac
    25621 tacaagtatt atttcaatgt ttatttgtaa cagctggaaa gcctcaattt ggattatggc
    25681 tagtgttagg tgctgggtgt gctaatataa ttcttgacta tgtgttcatt gttctgttac
    25741 aaatgggtat tagtggagca gcacttgcaa ctggagtagg atacctaatt cctaccattt
    25801 caggtatggt tttcttttca aaaaataaag ggttacttaa attttgtata cctagactag
    25861 ataaaagaat attatttgaa gcttgtttta atggttcatc tgaaatggtg ggtcaactat
    25921 caacagcagt tactactttt ttatttaatg ctatgatgat gaaattaatt ggtgaagatg
    25981 gggttgcagc tattacaata attatttatt ctcaatttct tttaacttcg ctttatatag
    26041 gtttctcaat gggtgttgca ccaataataa gttataacta tggaagtgaa aataatacgc
    26101 agttaaatca tgtttttaag atttgtatat tatttatttc agtagcatct ttattggtat
    26161 ttatcttttc tatatcatgt tcaccaatca ttgtagagat tttttctcaa agaggaagcc
    26221 gagtttatga aattgcaagg tccggatttt atatattttc ttttagtttt attttttgtg
    26281 gatataatat ttttacctca tctatgttta cagcattatc aaatggaaag gtgtctgcaa
    26341 tattatcttt tctacgtaca tttggattta taactatagg tttattgata ttgccaaata
    26401 tattaaatat aaatgggata tggttagcag taccaagtgc tgagatttta accttatttt
    26461 taactgtttt ttgtatattt aagtataaga atagatataa atatatgtag atattaaata
    26521 aatagcttag atagatattt tatgttttaa taagtaattc aattagtggt agatatatac
    26581 tattgaaaat taaagttata attgatataa agaattaata aaaataacat ataaaagttt
    26641 aaaagggagt tgaacttaaa gtttgattag aaaaagtcaa ttttaagaca actcctttta
    26701 ttttactatt gtattaatct gtatctgtaa gtgtattagt ctaatattat aaactttgga
    26761 tgaaattaat tttctatagg ttttaatgta tcatacactt tattttaaag aaacttatct
    26821 taattttcat agtgattgaa tttgtctatt agagatgtta ctattagtaa tgtaaaagca
    26881 agagtagtga atataaaaaa caagatagtg atactgcaag attagaatat aataaatttt
    26941 tatggagaga tttcaatatg gatacatgtt ttaataaaaa aatattactt gttgatgatg
    27001 aaaaggatat agtagattta attgaagaag tactcataaa tgatggtttt aaaaacatta
    27061 ttaaagctta taatggtcta gatgctattt cgctgtgtaa gatagcatgt ccagatgttg
    27121 tcattcttga tataatgtta ccagatatag atggtataga agtgtgtaaa aaaattcgag
    27181 agttttcata ctgttctatt ctttttttat catcaaaaaa tgatgatatt gacaaaatac
    27241 taggtcttag tagtggggga gatgactata taacaaagcc attcagtcca agagaaattg
    27301 cttttcgagt taaagcgcaa ttacgtagac aacagtatca aagcattgta ccatcagata
    27361 gtgaagttat taaaatagga gatattacta ttgatataga aggaaaccgt gtatataaag
    27421 atagaaatga gattgagtta actggaaggg agtatcatct tttaagctac atggctcaaa
    27481 atgtaaataa aattatagga aaagaaagac tctatgaaca agtatgggga gtatatagta
    27541 gtatttgtga caatacaatt atggtgcata tacgacatat aagagaaaaa attgaagata
    27601 acccctcaaa tcctaaaata cttataacag ttaaaggact aggatataaa cttgtgaata
    27661 gaatcgatta gaatagattt taatattaat gaagatatct caagttgaat ttttagttaa
    27721 tgaggcattc ttttatgggt gaaatcaaat gtattttcgt tatctcaaca atgaagaaga
    27781 ggtctatctc tattttgaga tagcctcatt aagtttatat cctggtaatg tactttatgt
    27841 tctaataaaa tttttttagt ttatttgcag tgaaacatta actagaacat taaaatttgc
    27901 attgaaatac caattaaata atattgtata ttgtgtataa acttatacta attgtttttc
    27961 tatattaaat actttatcaa tccaaccttt ataaaatttt tcttcatggg aaactaggat
    28021 tatacttcct ctaaactgtt tcaaagcatt ttgtaaagca tcctttgtct ctgcatcaaa
    28081 gtgattggtt ggttcatcca gaataagaaa attacaagga gataacatca tacaacataa
    28141 tttaacctta gattgttcac caccacttaa agtagataca ctccttgaaa catgctcttc
    28201 cttcacacca catctggcta gatgacgtct aatctctttt gtatttaatt ttggatattt
    28261 atctgctact atttgaagtg gggttttatc aggattttcc cattttaaat cttgctcata
    28321 ataaccaatt ttaacttgtt ctgaaaactg gaaatctcca gatatacgag gaatatcttt
    28381 gactaatgtc tttaacaagg tagatttacc gattccatta aaaccagtta taactatttt
    28441 ttgacctcca tcaacagaga aatttaattt tggaagtaaa gaatagtagt atccaacttc
    28501 aagatttgtt atagtaagag cattttgagc cgatatttca atttctgaaa attgaatatt
    28561 tggttttcct gtaaaactag gaggagctat tctttctatt ttatccaatt gtttttgtct
    28621 tcctcttgca atttttgaat ttactccagc tttattttta cgtataaatg tttcttcttt
    28681 ttctattttc ttttgttgtg cttgatacct tctaatataa tcttctctta aatgtgattt
    28741 ttgtttaagg aactctgaat attttccatg atatttctta atcatgccaa attctatatc
    28801 aagaatacct gtagaaattt tttctaaaaa gtcaaaatcg tgggaaacta caataaatgc
    28861 cccattaaat gtatttaaat aatttgagag ccattcaaca tgctctttat ctaaaaagtt
    28921 tgttggttcg tctaataata gaacatcatg gttagaaagt agtaattttg ctaaaattac
    28981 ctttgccctt tgaccaccac taagctctct aacaacacga ttcattccta ttgaatctaa
    29041 tccaagacca tttgctattt tatttatttc attatctata gaatagaaat tacttgctat
    29101 tagttgttcc tgataatctg atgctttgat tagatattgc tcattttcag atatagcact
    29161 tttttgatag agtaaattca tttccttttc tattttataa agttcttcaa atgcagtgtg
    29221 taaatagagt gatattgttg tatctctatt gatttctgca tattggtcta aatggcctat
    29281 attgatatta ggttgccact tgatttctcc tgaatctgga acaacttctc ccaataaaat
    29341 tttaattaat gtacttttac ctgtaccatt ttggccaact acacctatat gttcaccttt
    29401 gaataaatca aagttagctt tctcatacag tgatttatcc ataaaacatt gtgataaatt
    29461 agttactttt aataaactca taattcaaac tccttttctt ttattaaaaa atttatggaa
    29521 ataaaaaaag cagaggaatg gcattgtaaa atgccgacct ctgcttttgg aaaaacaaaa
    29581 ggtcatagac aagcattgtt gtctatgacc agaaaatcta tattatctat cggcaaatag
    29641 gtaattttaa ataagcatag ccaaaaaact atactaaacc tatatttgcc gatgaagata
    29701 gaaagcttta agctttcaga ttaacctcta cacaacgctt catcgtatac atttgtgtag
    29761 agttaagttt tctaacaagt ttaactaatt ctatataaat cataattatt cacatcctaa
    29821 tcttagtatt aattctagtt tatctgtatt taaattgtac ttttgtactt tgtggattat
    29881 cttatttatt taaaatatgt tttattaatt atagcttaag ttatgttatc ataatactta
    29941 gttatagtca ataagaaagt tatatttact attattatat taatttagta aatctatcat
    30001 tacaaagtta tttgaagact cgctatcaat aaaattttat agtctataag aaaattaaga
    30061 ttatgagttt tataattttg atatagggat actattttca taaatattac aacatgtaga
    30121 agtatatgtc tattattgtt gaattttcaa tgatatatta aggttctaat atattataca
    30181 aaataaaaac attaattcaa cttaaataat tttaagtatt atatgtgttt tgattaaaga
    30241 aaactaaaat tttaaggaaa aataacatat ttgtattaaa ttttattgaa atgattaaat
    30301 ttatttactt aatgtaaatt attagctaaa attgtattaa ataattaagg aggtgagtag
    30361 ctctggatga aatagattta aaaataatta attctctaaa aaagaatagt agggcttcaa
    30421 cctctgaaat aagcagacaa attaatttat cagtaccagc agtctcagag cgtataagga
    30481 aaattgagca gtcaaattta attcaaaagt acactattca aattaatcgg gaaaaaacaa
    30541 aatataagct tttggctttt atatttatca atactgattt atctaaaagt atgaaagaat
    30601 ttaagaaaac tatattggaa tatgatactg tattagaatg tcatcatatt tcaggagagt
    30661 atgattactt aataaaagta ttagcagaag atacaagtaa tcttgaagag tttatatcag
    30721 tgactttgaa ggaaattggg gggattcaaa aagctaatac aaccattgtt ttatctacaa
    30781 ttaaagaaga atttaataca ataaaagata ttttttaaat aatttactag taaagtgtta
    30841 attatatttt aggaggaaaa tagaatatga aagttttagt ttttttagca aaaggttttg
    30901 aaactatgga atttagtgta tttgtagatg ttatgggatg ggctcgtaac gattatgggc
    30961 atgatattga tgtagtgact tgtggattta aaaaacaagt tatgagcaca tttaatatac
    31021 aagtattagt tgataagacg atagaagaag tatgtgttga tgattatgat gctctagcta
    31081 ttcctggagg atttgaagaa tttggatttt atgatgaagc atatgattca tcttttttaa
    31141 atctaataag ggagtttaat tcaaaagaaa aaataatcgc ttctatttgt gtggcagcat
    31201 tgccagttgg aaaaagtggt gttttaaaaa atcgtaaagc tactacatat catttgaaaa
    31261 atggtaaaag acaaagacag ttaagtgagt ttgatgtaaa tgtagttaat gaaccaattg
    31321 ttgtagataa aaatattata acctcatatt gtccagaaac agctccacat gtagctttta
    31381 agcttttaga aatgttgaca tctaaagaac aaatggatga agttaaatta gcaatgggat
    31441 ttaaactgta atggtttata gattttctaa gtaatcagaa ccccagtcac acatggaatc
    31501 taaaattgga ataatactct ttccaaaatc agatagcgag tattctactt ttggaggaac
    31561 aacaggataa accactctta taattaaacc atctgattct aattcacgta attgttgagt
    31621 taacatctta ggcgttgctt taggaattaa tttttttaat tcattgaacc tcaatatagt
    31681 gtctttaaga tgccaaagta taagtgtctt atatttacca ccaatcaatg caagtgttgc
    31741 ttctattggg caactgtaat tatctaaaca ttttttcatt tttgggctcc tttatttatt
    31801 ttaaagtatc tttttaggta ctatattaca aaaaagtgca ttattgtaat atagtaccat
    31861 agtgataaaa ttatagcata ggttaaataa atcatcaact tagcctaata aaacaatagg
    31921 gggtaaataa atgaatttcg ttgaacttgc aaaaaaaaga tattcttgcc gtaattatca
    31981 agatagaaag gttgaaaaag aaaaacttga gaaggtttta gatgttgcaa gaatagctcc
    32041 aactggtggt aatcgtcaac ctcaaagatt gattgttatt caggaaaaag aaggtataaa
    32101 taaactttct aaggctgcca atatatatga tgcgccatta gcaattcttg tatgtggaga
    32161 taaagacaaa gtttggacaa gaccttttga tgggaaacaa cttacagata ttgacacaag
    32221 tatagttaca gaccatatga tgttacaggc aactgaactt ggattggcaa gtgtttgggt
    32281 gtgctatttt aatccagata taattagaga agagtttagt ttgccagata atctagaacc
    32341 aataaatata ttattgatgg gatatgaatc taagatacca gagagcccag agagacatga
    32401 aaaaactcgt gttcctttaa gtgaaattgt ttcttatgaa actctttaat tataaaatta
    32461 agttattcat aggataaatg taataaagtg tttgttataa acaaaattca aaataaataa
    32521 tatctacata taattaattt tagtgaagta tatctagttt aactagaatg tatacttcac
    32581 taatttattt attcaaaata tttatgagga ttttaatata ttaactaaaa tatatcaatt
    32641 gaattaactt ttaaatctgg aaaagcactt gaaatatagt gttttatatc atttaaatgg
    32701 tcttgaattt gcttttctga tattttatca ggtccatata caaaatacat aatattttta
    32761 gtatcttttg ttatagctgt tcgattatca gggccattaa gaatactaga taatatacca
    32821 atattatctg ataaaaataa atcatctttt gttaaaatat gttctttacc acctatacca
    32881 taaaaatgtt cacttccatt tgctaattct attttcaaag gtaattccat tttatcaagg
    32941 tcatgacctg ctgttagaag aagatttttc aattctgcta aaaacattga ctcaattgtt
    33001 acacctacat ctgggatacc ttttgatttt aatagaatag attctaattg aagcaataca
    33061 gggtaagttt tcttgaattt tttataatac tttatataac ttgaaacagg ctctgtttta
    33121 attttttctt tgcgattgta ttctgggtgt tgttctataa tatttttaat tgtagagttt
    33181 ttaagaacta aaaaattttc tttattaggt tttgaatgtg taatatttat aaccataact
    33241 ccaaatttaa tattgggata aatttcttta actttatgtg atacctctaa cataatatag
    33301 actccttttt attttatatt ttatgatata atcttagcaa attaaaagtg gattttatag
    33361 ttccattttt atagtaattt tatagaacca cttttggagg tattagaatg tggattacga
    33421 ttaatagaaa tagtaatata tcattatcaa gacaaattta ttgtgagata aaagatatga
    33481 ttctggatgg aagcttaaag tttgagcaaa aactgccatc atctaggact ttatcaaaag
    33541 aactatctgt atctcgtaat acagttttag atgcatataa tcaattaatt gcagaaggat
    33601 atttggaaac aaggaatgga tatggaacaa ttgtagctaa aggaatatca gggcataaag
    33661 ttgattttaa gttaaatgat acttttagag atgaaaaaga tttacatact aataaacaaa
    33721 aaaattatat agattttcgt tcaggagttc cagaattaaa actatttcca cgcaaagaac
    33781 tttcaaagct atataaacaa atactgtatg atttatcaga ttcggatttc agatatggaa
    33841 gtacagctgg tgtatgggtt ttaagagtgg aaatatctaa gtatttattt cgtactagag
    33901 gaattagatg taatcccaaa aacattatga ttgtttctgg ttcaacacaa ggtttatctt
    33961 taatttcaca gcttttatac aaaagtaata aaaaggttgc tgtagaagac cctattcata
    34021 aaggcttatt aaaggttatt tcatctattg gatattcagt tgttggaatt aaagtagatg
    34081 ataagggaat gaataccaac ttaataaaat caataaaggg gatttctttt gtttatacta
    34141 caccttctca tcaataccca ttaggaggga ttttacctat tcaaagaaga ctagagctta
    34201 ttaaatgtgc aacagagaat gattactata taattgaaga tgattatgat agtgaattta
    34261 gatatgaggg tcaaccaatt agttctcttt atgaacttag cccaaataaa gtaatttaca
    34321 taggttcttt tagtaaaata ttatctccag ctattcgtgt tggatttatg ttattaccag
    34381 acaatatttt agaaagctat aaaaccttaa aaatgtactc tgatgttcat acagaaacaa
    34441 tattgcaaca tgtattagct gaatttattg gaaatggagg tttagagaag tacatattta
    34501 gaatgaagaa gttgtacaat agaaaacgta agtacctcat aaaagtttta aacacggaat
    34561 ttaaaaatga atttaaaata aaaggtgaag cagcagggct tcatatagtt gctcatttct
    34621 ataatgttaa atttacggaa agtttaattc ataaaatttt tgaagcaggt ataaaagttt
    34681 atcctataca acaatatgca attgagaata tattagaata tgactatgaa attatactag
    34741 gttatgctca tcttagtttt gatgaaattg aaaaaggtgt aaaaatactc agcaaaataa
    34801 tacatatgaa tcaaggtaca tagataaaac atgtagcaat ctacatataa tagatgtaat
    34861 taagtttaaa ctttaaaaga aatatatatt aatatttttg tataaaaata cctgatattt
    34921 ttttatcgat actttattgc tatacactaa attaagatag caatttatat taagaaaaaa
    34981 ctttttgcat aggttataat acttaaaagg agaggataga gttgaaaaca aatacagatg
    35041 ttattatgga gataattgat tatatagaag aaaatcttac agaaaatcta aatttagata
    35101 aaatagctta tattgctaat tattcaaaat accatttaca cagaatgttt acaaatgttg
    35161 taggatgtac tatccatcaa tacatacaga ggaggagact tactgaagca gctagacaac
    35221 ttatatttac agacaaatat attatagaca tagctattac agtaggatat tctacacatc
    35281 aatcttttac actagcattt agaaatttat ataaagaatc tccacaagta tatagaaata
    35341 aagatgaatt ttatcctatt caacagagat ttgttttaaa tctaaatcat caaattcaaa
    35401 gtgaaaaatg tatttcttat gcaaatatga attataaaca aagaagagat gaaatcaatt
    35461 cttatcttaa ctttaatatt aattgtgagg tgaaagtagc atgagtttag tgccacatgt
    35521 aattgaacaa acaggtcaag gggaaaggtc ttatgatata tattcaaaat tattaaaaga
    35581 tagaattata tttataggag aagaaattaa tgatgctatt gcaagtttag tagtagctca
    35641 attactgttt ttagaatcag aagacccaga ttcagatata attatatata taaatagccc
    35701 tggtggctct gctacatcag gatttgctat atatgatact atgaattatg tcagatgtga
    35761 tgtatcgact atttgtattg gtatggctgc aagcatgagt gcttttttac ttgcaggagg
    35821 aacacatgga aaaagatgtg ctttacctaa ttcagagatt atgattcatc agccaatggg
    35881 aggagctaaa ggtcaagcaa cagatgtaaa aatagctgta gataatatat tgaaaataaa
    35941 agaacgatta gataaaattc tttctgaaaa tacaggtaaa tcaatagaag atattaggag
    36001 agatacagat agagataatt ttatgactgc actagaggct aaagagtacg ggctgattga
    36061 ttatataatg aataggaatg aataaagtat caaagtatca tattaaaatg tctgttttac
    36121 aaatatatat ataatattaa ataagagtgt ctcaaaatga actttttagt ttatgggaca
    36181 ctcttttttg tatgaaatta aatatggttt tatcatttca acaattatta ccaaatttca
    36241 agtttaataa attctactat aaaaaataca taaaagataa ggttctttag taactttctg
    36301 tcgtcaaaag tttttataaa tttaataaca aaacaagaga aaataccata tattacttat
    36361 gtctgcaata tatagaagac aaaggagttg tacattatga ttacaataag tttgtgcatg
    36421 attgttaaga atgaggaaga agttataggc agatgcttag aatgtgtaaa ggatatagta
    36481 gacgaaatta taattgtaga tacaggttct acagattcca caaaagaaat agtctcaaaa
    36541 tatacagaca tggtgtacga tttcgaatgg atagatgatt tctctgctgc aagaaatttt
    36601 tcattttcta aagcttctaa agactatact atgtggcttg atgcagatga cataatttta
    36661 gaagctgata gagaaaaatt attaaagatt aaagaaagct tggatacttc cattgatatt
    36721 gttatggcaa aatacaatgt atcctttgat gaaaatggta acccaactct ctcgtattat
    36781 agagaacgat tgtttaaaag aagttctaat cataaatggg ttgaccctat tcatgaagta
    36841 gtacctcttt ttggagaggt attttattct gacattgcaa tatctcataa aaagcttcat
    36901 agacaggacc ctctaagaaa tcttagaatt tttgaaaaaa tgatttcaga aggaaaaaca
    36961 ttggagccaa gacaccaatt ctattattct agagagttgt actataatgc taggtataaa
    37021 gaagcaatag aaggttttac taagttttta gactcatcaa gaggatggat tgaggattgt
    37081 atcagtgctt gcagagattt agccacatgt tattacttaa ttaatgatga aaaaagtgcc
    37141 ttatattcat tgtttagaag tttcgaattt gatgagccaa gagcagaaat ttgttgtgac
    37201 ataggaaagc atatgtttga tagacaaaaa tataaagaag ccattttttg gtataaggta
    37261 gcattaacaa gagataagaa tgatactaat ggaggtttta agtcaaatga ttgttatgga
    37321 tatataccat ctatacaatt aagtgtctgt tatgacaggt taggagaatc agataaagct
    37381 atttattatc atgaaaaaac aaaagaaatc aaacctaacg atagtgctgt tttgcacaat
    37441 gaaaattatt ttagtaaatt taaaaatagt tgataggtca caatcatact aaatttgaca
    37501 tattatatat agagcttaaa agctcaaata tatcaggagg tgcttttaat aatgagtaga
    37561 aataaatatt ttggaccatt tgatgataat gattacaaca atggctatga taaatatgat
    37621 gattgtaaca atggtcgtga tgattataat agctgtgatt gccatcattg ctgtccacca
    37681 tcatgtgtag gtccaacagg cccaatgggt ccaagaggta gaaccggccc aacaggtcca
    37741 acgggtccaa caggtccagg agtaggggca acaggcccaa caggaccaac cggtccgact
    37801 ggtccaacag gaaatacagg gaatacagga gcaacaggat taagaggtcc aacaggagca
    37861 acaggggcaa caggcccaac aggagcgaca ggagctatag ggtttggagt aacaggtcca
    37921 acaggcccaa caggagcgac aggagcaaca ggagcagatg gagtaacagg tccaacaggt
    37981 ccaacgggag caacaggagc agatggaata acaggtccaa caggagcaac aggggcaaca
    38041 ggatttggag taacaggtcc aacaggccca acaggagcaa caggagtagg agtaacagga
    38101 gcaacaggat taataggtcc aacaggagcg acaggaacac ctggagcaac aggtccaaca
    38161 ggggcaatag gagcaacagg aataggaata acaggtccaa caggagcaac aggagcaaca
    38221 ggggcagatg gagcaacagg agtaacaggc ccaacaggcc caacaggggc aacaggagca
    38281 gatggagtaa caggcccaac aggagcaaca ggagcaacag gaataggaat aacaggccca
    38341 acaggtccaa caggagcaac aggaataggg ataacagggg caacgggatt aataggtcca
    38401 acaggggcaa caggaacacc tggagcaaca ggtccaacag gagcaacagg cccaacagga
    38461 gtaggagtaa caggagcaac aggagcaaca ggggcaacag gagcagacgg agcaacagga
    38521 gtaacaggtc caacaggagc aacaggggca acaggagcaa atggattagt aggcccaaca
    38581 ggagccacag gagcagcagg aacacctgga gcaacaggtc caacaggagc aacaggccca
    38641 acaggagtag gaataacagg agcaacaggg gcaacaggag cgacaggtcc aacaggagca
    38701 gatggagcaa caggtccaac aggagcaaca ggaaatacag gagcagatgg agtagcaggt
    38761 ccaacaggag caacaggagc aacaggaaat acaggagcag atggagcaac aggtccaaca
    38821 ggagcaacag gggcaacagg agcagatgga gcaacaggtc caacaggagc aacaggagca
    38881 acaggagtgg caggagcaac aggagcaaca ggtccaacag gagcaacagg agcaacagga
    38941 gcagatggag caacaggtcc aacaggagca acaggagcaa caggggcaga tggagcaaca
    39001 ggtccaacag gagcaacagg ggcaacagga gttacaggag caacaggccc aacaggccca
    39061 acaggagcaa caggagcaac aggagcaaca ggtgctagtg caataatacc ttttgcatca
    39121 ggtataccac tatcacttac aactatagct ggaggattag taggtacacc tggatttgtt
    39181 ggatttggta gttcggctcc aggattaagt atagttggtg gagtaataga ccttacaaac
    39241 gcagcaggaa cattgactaa ctttgcattt tcaatgccaa gagatggaac aataacatct
    39301 atttcagcat acttcagtac aacagcagca ctttcacttg ttggttcaac aattacaatt
    39361 acagcaacac tttaccaatc tactgcacca aataactcat ttacagctgt accaggagcg
    39421 acagttacac tagctccacc acttacaggt atattatcag ttggttcaat ttctagtgga
    39481 attgtaacag gattaaatat agcagcaaca gcacaaactc gattcttact agtatttact
    39541 gcaacagctt caggtctttc attagttaat actgtagcag gatatgcaag tgcaggaatt
    39601 gcaataaatt agattagata agaaaaggct tctaatatcg tattgatatt aggagctttt
    39661 ttaagaatga ttgatgaaca tagttttaat attaattagt gcgcatatta taaaatacta
    39721 ttatataata taaaataata acattaaatt ggaaatatag aattatctag gggtgatact
    39781 atgaaaaata agattgaaat atcaatgaac aactttgtaa aaaattatca taaatcaaat
    39841 aatataacta caaagtggca agaacttttg tttgcttatg catctgctga agatgatatg
    39901 tttcagaagc taaaaagtgt tgtaggaaca tctcatgcta tgccaaaaga ttttctggaa
    39961 aatggaaaaa ctataattac atattttata ccttttgatg aaagtgtaaa taatagtaat
    40021 attggagggt ttgaatgttc tgaaatatgg gcaagagcgt acatagaaac taatatgttg
    40081 atttcaaatt taaatgattt cttatgtgaa gaactagaga agataggggc taattcatat
    40141 gctattcctg ggtcgtataa ttttgacagt gaaaaattgg taagtgactg gtcacaaaga
    40201 catgtagcat tcatagcagg tcttggaact tttggtttaa ataatatgct tattacagaa
    40261 aaagggtgtt gtggaagaat aggaagcata atcacaagtt tagaattaga gccaactaaa
    40321 agaccagaaa atgaatactg cttgtataaa cataataata gttgcaaaaa atgtgtcaat
    40381 aaatgcgtga aagaagcttt aaaagaagat ggatttaata ggaataagtg ttatgaaatg
    40441 tgtatgataa atgaaaaaaa atacacttat ataggtggat gtgatatttg tggaaagtgt
    40501 atagttggag ttccttgttc agtaataaac ccatcaagat aatggattta agttgactaa
    40561 taattttaaa gatagtttat aatgaaaaaa ttttagttat caaaataaat ataatataaa
    40621 aactaaataa atgtgtttaa aaaatggata aataatttgt gttgattgac aaccagttat
    40681 actgttgata gacttatatg tatcgctgtg atatataagg agggttgaga ttttatgttt
    40741 gatttaatct ttatttttgc atagcaaggg ctattgcaac tatgaaattt aatatataaa
    40801 tagccctttg ctattcctaa tgaaaaatta ctatttaata ggagagcaaa atgagctata
    40861 aaaaagcaat acatatatta ccagaagaat tacttgaatt aatacaggaa tatgtagatg
    40921 gtgaatgtat ctatattcct agaaaatcta ataataaaaa agaatgggga agtaatacac
    40981 ctactcgtga ggagttgtca attagaaata tgcagattta cgaagactat caagttggat
    41041 atgatttgca atatttatcg gaaaagtatt atttatcttt gaaaagtatc caaagaattg
    41101 tattacaaga aaaaagaaaa gatatctaag gatgagccag tatagtttta taattatact
    41161 ggctcatttt cttttgataa aagtgtttga ggtatagttt cttttaagtg gatgatataa
    41221 tttaagtaat ttcaataact tatacagtag ctaacaaagc tggttgtaaa gtatctaata
    41281 agaagtagta gctttttata tgtttgaaat taaaatttat taaaattagg aggtcttgtt
    41341 ttgaaaaaaa tacttgatta tattccacct tttcataact ttctattaat ttagtaatct
    41401 tatagaaagg aaattgcatt tatgaaaaaa attacttggg aggtggaata tatctcccag
    41461 ttacctgtaa ttaggtattg taaaaaatgt ggaaaaaaga ctgaatatat ttgttcaggt
    41521 ttatttaggg ttaatgctca acataaatat ttggatatat ggttaatata caagtgttca
    41581 aattgtgatt caacatggaa ctcaactata tattctcgtg ttaatccaaa aagcttaaat
    41641 ccagaaatac tagaacaatt ccatacaaat gattataatc ttgttaagca atatgctatg
    41701 aatatggaac ttttacatag aaatggagca gaagttggta ttccagagta taaaatagta
    41761 ggacaagaaa ttaatattaa tgaccttaca caagttcata ttattagtaa atatccatgt
    41821 cagttaaagg tatcaacatt attacgtgag aaactaggtt tatctaggaa ggtatttgac
    41881 gaaatgttgg attgtgggat tattagaagt aactcaggag ttgatttaaa gaaaggtaaa
    41941 ttaaattatg aaattatgtt agatataggc aaggagaagc aaaagtcttc aaattgatta
    42001 gaataactaa cttaatatat tttcaggaac atcatttaaa aaaatagtga ctttaaaaaa
    42061 tttaaagcca ctatttttta atatgtttta tctatataac tattattttt ctaggttttt
    42121 taatatttcg taatagtgtg ttgtggctat ttcacttgac tcgccttttt tacaaaaaga
    42181 taatttagat agttttggaa ctacacgttc aacgacaatt ttattaccta tcattttaga
    42241 ttcaagtatc ttcaatgctt ctaaaaatct cttatccttt tttgcacgat tataaaatga
    42301 taaaacgtag acataaagga ataggttata attacggaaa ggatattcaa cttgcataaa
    42361 taatgtgcca attccatagt gacaagggcc gattggtttt ttaatagtcc aatggtcaag
    42421 tagaaaatct acagctttgt caagttttga ttctttattt agataattac taaaacggaa
    42481 tgcatttaat atattaagag ttggtagtgg atttgagtat tcagtttctg gacctcgacc
    42541 aaaactaaat ttattgcaac gccacccacc atcagtatac tgtgtatcta aaaaatgttg
    42601 aaacgttttt tgcattctaa tgtcagatgc atatcccata tgacagagta cgttagcagc
    42661 atttgcagta tgacaagggt aaatacctcc atttggatat agtttgaaac gtccatcttc
    42721 tcgccatgtg ctaaatatca ggtcagcaca ttctttaagt aaagtatcat cagggttcac
    42781 acctaattct aatagataaa gtacactatc aagagtagag aaaggagaac cttttattaa
    42841 acgcttatca ggtgtagtcc aatagtctgc accattatca tacctgtgtg ataatattat
    42901 ttcaatatct gataaagatt gattttctac attcattttt tactccattt catattatat
    42961 tctattaaat ctatcaaaaa ctttattata atattattta tatttataat tgatttattt
    43021 tatttaaaat tgcatttata gctgtatcag gaacaactgc taaatcttct gcattgaagt
    43081 aataaactat attagaatca aataatatat ttgaatttgg aggaaattca tcatctccaa
    43141 accaaagtat aaataccata gatgtattac ccatatatgt aaacctataa gctaaatctc
    43201 ccatgtttac tttttcagct ccaattttct ccataactaa cttatatttg tctatttgag
    43261 atgtaaaaac ttctgaaagc ctatatagag tcctgtttaa aaaatttgga taataaacat
    43321 tgcctcctgg tatttcttta aaagttacat atttattagt tctaggaata cctttagcat
    43381 tgattaaata tctaactatc aagattttaa gctcaaagtt attgcaaagg ctaccattac
    43441 tattccaaac ttctccactt ggatagtcta taatatattg tctatcaaaa aaattgagtg
    43501 tgaatctatt taaatcatta ttgaaaggta tattacttaa attactaatt gtatgagggt
    43561 ctaattcttt gagttttttt cgaacatagt caaatggaac attataatta ttttttgtta
    43621 tcttttcatc cataattttt tcctccaatt taaacaatta aaagtatatt tataaaaagt
    43681 tttcttatta ttaattttat tatatattca aaatattaca ataataaatt gttaaataaa
    43741 tttttatatt taagtaaata cgtgtaaaat gaatataaag tttttgaaat ataaagtttt
    43801 tgtatctaaa atattttatt tgtaaaatag taattaatta ttgtaagcta taatatgaga
    43861 gtattatggt taatgtgaat tttaaagata ttattaaata tataaattag aatactatta
    43921 aacggataaa tggaggagtt attatgtcta agatattagt agtagatgat gagttagata
    43981 tgttaaagtt gattgaaaat gtgttgaaaa gagatggaca tgaagtaaag gtaattagtg
    44041 atgtagaaaa agctatgaac atggatttta attattttaa tctaataata ttagatgtta
    44101 tgatgcctaa gatggatggt tttgaagtat gtaaaactat aagaaataag gttgattgtc
    44161 caatactgtt tttgacagca aaaaatatgg aaagtgatat tatgtacggt cttggtatag
    44221 gtgcagatga ctatataacc aaaccttttg gtgtaggaga attaagggct aggataactg
    44281 ctcatttaag gcgagaaagt agagaaaaaa agaatttatt aactatctca aatgttcaat
    44341 ttaacttttt aggcaaagaa gtttcaattg atggtaaaaa aattaatttt actaaaagtg
    44401 aatatctaat atgtgaattt ctagcaaaaa ataagggaca agtattttca aaagaaagaa
    44461 tatatgagtc ggtatatggt tttgatggag aaagtgatat aagtactatc acagagcata
    44521 taaaaaatat acgaagcaaa ttaaaacaat atgatattta tacaatagaa actgtatggg
    44581 ggatagggta taaatgggtg taat
//
LOCUS       DAEPHU010000027        43902 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 01A10CD0081
            SAMN05941466-rid12468953.denovo.027, whole genome shotgun sequence.
ACCESSION   DAEPHU010000027 DAEPHU010000000
VERSION     DAEPHU010000027.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941466
            Sequence Read Archive: SRR6291087
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 43902)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 43902)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068158.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 22:43:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,892
            CDSs (total)                      :: 3,805
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 87
            rRNAs                             :: 8, 1, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 55
            CDSs (without protein)            :: 55
            Pseudo Genes (ambiguous residues) :: 0 of 55
            Pseudo Genes (frameshifted)       :: 21 of 55
            Pseudo Genes (incomplete)         :: 28 of 55
            Pseudo Genes (internal stop)      :: 16 of 55
            Pseudo Genes (multiple problems)  :: 8 of 55
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..43902
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941466-rid12468953.denovo.027"
                     /strain="01A10CD0081"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            41..1063
                     /locus_tag="KR231_001588"
     CDS             41..1063
                     /locus_tag="KR231_001588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0003970.1"
                     /translation="MVNWEIKKLAKSKSMFISLGILVLILMISIFITPVLETESYYID
                     KEKGRIEDTRSGIDIGNEKFQNKINVLKQFSNQTDTGEFSKKIELMSKKKLDNLSVNE
                     YKDISFWKVFNYRVTNSLINVGMLIIISIIISNIYVDEVVTSVKDIILSSKEKKKALN
                     SKIFVALLVPLVIYSVYLMGIFIITCMQQGVPVNGDLESFRIVDNVVALKTNLSITKY
                     VILNIGIELLMFEGWAMIAIFGSFISKSSISSISFFIFIISITKIMSVIHILPKKLLS
                     VVSNVNYYDLIFGFNKIIGNYLGDIMIFKVNIDIVNIAIGLLMAILIGAMSLCFLVIK
                     SDYISR"
     gene            1077..1964
                     /locus_tag="KR231_001589"
     CDS             1077..1964
                     /locus_tag="KR231_001589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011948651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH0003971.1"
                     /translation="MNKLEIENLSKIYGKKVANDKITVTLENGVYGLLGPNGAGKSTL
                     MKQITTLIKPDEGQILYNGEDIFKMDADYRNILGYLPQEFGVYKNFTAKEFLQYIGAL
                     KGLRGKYLNSKIGELLDLVGLYDVRNKSIGKFSGGMKRRAGIAQVLLNDPKIIVLDEP
                     TAGLDPQERARFRNLIAKMSRDKIIILSTHIISDIESVAKETIMIKDGKLLMKGTHKD
                     ILSHMENKVYNVQVKNECEVDDIQSKYKVVSIQSDINSIVLRIVSEDIPSEDNIQPVQ
                     AKFEDVYMFYFDLEDAREV"
     gene            1970..2743
                     /locus_tag="KR231_001590"
     CDS             1970..2743
                     /locus_tag="KR231_001590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBH0003972.1"
                     /translation="MMYLVKAEMIKILKSKSVWIIWLFLIFFGFFLIRKFDVLDTYAD
                     IFYKIEGSIPLIGLIMFIITSGNYIKEYDSNMTGLINTTKKGKKSVVLSKLVANGLIL
                     SIINISFILLVGIRGFSFFDFKNLNESIHNLWYFGNSNLNLTVIQMYIIVILTTIFAS
                     FIFAQIGLTLSSIFKSAVIPFILGGLIMAIPYFSVGFIPDKAIKFMSVTPNWIMMSQQ
                     MVKYNVPSILIVFSIVISIILMIVLTKITYENFTSSKRF"
     gene            2855..3580
                     /locus_tag="KR231_001591"
     CDS             2855..3580
                     /locus_tag="KR231_001591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012450879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBH0003973.1"
                     /translation="MENRVLIIDDEVEILKLLETVLKKEGLNNIYTAKTKKEGLELFK
                     SINPDLIVLDIMLPDGEGYDICKEIRKTSNSPIIFLSAKTEELDKLLGLAIGGDDYVT
                     KPFSPKEVAFRVKAHLRRLSYFSDAQNESKNLNNNEEKIISFGPYILNESRAELIKDG
                     KSIGLFAKELKILSLFAHNQNQIISKEKLWDKVWGEDYVGFDNTIMVHIRKIREKLED
                     NPSKPEYILTIKGLGYKLAVKED"
     gene            3584..4987
                     /locus_tag="KR231_001592"
     CDS             3584..4987
                     /locus_tag="KR231_001592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBH0003974.1"
                     /translation="MKWKITRNFIFTIVFVAISVVIINIISILYVISTNSFFKVVDSG
                     NNPEEFARSFEKDLYEKDGEFKLSKIGAEKLEKSNSWIQVLNDLGEEVYGVNVPKDTP
                     KKYTPFQMVNNYKYIETKYVNFVLEKYLNKKHLNIIVGIPSRDISRIILTYSQNNIKK
                     TLNKVIIITLVIDSVVALGVGYLFSRKLTKPISSVLWSIETMANGNYSLYLKDRGIYE
                     EVFKNINMLADTLRVNEVERKENEELREEWLANITHDIKTPLASIQGYAEIINDKDYE
                     FEEDEIQEYTEIIYNKSKYIKDLVDDLNLSTRLKNNTIVLDKKKINLVSLVRDIIIDI
                     LNDNRYKNRNIEFESNEDLIEVYVDSILFRRAITNLIFNSIVHNSEGTLISVEIVKKD
                     NIEIIIKDNGIGISKSDLKHIFKKYYRGTNTGEMHKGSGLGMAISKEIIEIHKGKIYV
                     SSEIGIGTKIIIEIKQN"
     gene            4998..5822
                     /locus_tag="KR231_001593"
     CDS             4998..5822
                     /locus_tag="KR231_001593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein TraX"
                     /protein_id="HBH0003975.1"
                     /translation="MDFFKKGISGFTIKILALIFMTFDHIAAFMPQTMQIPIWFHWVG
                     RISAPLFIFMAVEGFYHTSNRKKYISRLYIWSVIMAIGNQIINNVFSHPEGAIIINNI
                     FSTLFLIAIYLQAIEFIKKFRKEKEIKYFIIGLLMIIIPIILGIFTVALLFKVTNRVI
                     ALFMILVPVPFLVEGGPIWIILGIIFYLCRGKKFSLSICYVLMCIFIFTTMSNGDYSL
                     KNSILQNYQWMMIASLPLMLLYNGEKGKSMKYLFYLYYPIHVYILYILGIYLINGF"
     gene            complement(6147..6767)
                     /locus_tag="KR231_001594"
     CDS             complement(6147..6767)
                     /locus_tag="KR231_001594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin family protein"
                     /protein_id="HBH0003976.1"
                     /translation="MKVLLINGSPNQYGCTYTALNEITKVLSKHDIKTEILYLGKETI
                     PGCISCASCFETGKCIRNDKVNKLIEDLDNIDGIIIGSPVYFSSATGQLTSFLDRLFF
                     IAGSRMATKLGASVVSCRRGGASATFDQLNKYFSISNMPIVSSQYWNQVHGFTPEDVM
                     KDEEGLQTMRTLGENMAWLLKCISAGKKAGIKEPQYEETIMTNFIK"
     gene            7033..7365
                     /locus_tag="KR231_001595"
     CDS             7033..7365
                     /locus_tag="KR231_001595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBH0003977.1"
                     /translation="MSIDCISNTDLSETGFSYTLSLISGKYKMIILYCLVEFEVVRYN
                     ALKRYINTISYKTLSLSLKELEADNLIIRTEYPQIPPKVEYSLSERGKSLIPILDAMC
                     EWGERNRP"
     gene            complement(7485..8126)
                     /gene="pcp"
                     /locus_tag="KR231_001596"
     CDS             complement(7485..8126)
                     /gene="pcp"
                     /locus_tag="KR231_001596"
                     /EC_number="3.4.19.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyroglutamyl-peptidase I"
                     /protein_id="HBH0003978.1"
                     /translation="MKILLTGFDPFGGEPINPAQEAVERVNNNINGAEIIKITIPTVM
                     TKSVEAIDKAIQEHNPDIVISVGQAGGRFDITPERVAINIDDFRIKDNEGNQVIDTII
                     KEDGEPAYFSKLPVKAMVKHMNENKIPASVSNTAGTFVCNHVMYGILYMIDKKYPNIR
                     GGFIHIPYTTSQVIDKKNTPFMSLEEIVKGLELAIEACIIYKEDVKEIGGEIS"
     gene            complement(8147..9079)
                     /locus_tag="KR231_001597"
     CDS             complement(8147..9079)
                     /locus_tag="KR231_001597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF979 domain-containing protein"
                     /protein_id="HBH0003979.1"
                     /translation="MQNFINISLEIFYALMGFLMIVIAYKSFTTINNNKKYGTSLFWI
                     LISLPFIFGRLIPANIIGIILILSSLLTLSKQVVFAKYEEPDENFGKEQADKLKNKIF
                     IPSLILAFAAVVVAMSLSNFDNSSQFAIGVGSIIALISALIITKAKPATSVQDGSRLL
                     QQMGPASMLPQLLVALGALFTQAGVGEVISTMISGVVPADSRLFGVIAYVLGMVIFTM
                     IMGNAFAAFSVITAGIGIPFVLSQGGNPAIIGALALTAGYCGTLLTPMAANFNIVPAA
                     LLECKNDYIVIKYQAPVALVLIIAHILVMYFLGF"
     gene            complement(9101..9766)
                     /locus_tag="KR231_001598"
     CDS             complement(9101..9766)
                     /locus_tag="KR231_001598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF969 domain-containing protein"
                     /protein_id="HBH0003980.1"
                     /translation="MIKLIGILIVVIGFILKIDTLFTVLLAGVATGIVAGLDFNQIFT
                     ILGDSFVSNRGVSLFILTLPVIGVLERYGLKQRAVSLIEKLKRLTTGKVLTIYMIARQ
                     IAGALSIRMSGHPQFVRPLVNPMAQAAGLSNSDELKESDEEAIKALSAASENYGNFYG
                     QNLFAGSSGVLLIASTLTQFGYNVTGLNIVKASTIMAVIALVVATIQFTLYDKKLNKS
                     HKK"
     gene            complement(10336..10809)
                     /locus_tag="KR231_001599"
     CDS             complement(10336..10809)
                     /locus_tag="KR231_001599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin"
                     /protein_id="HBH0003981.1"
                     /translation="MNTIIIYSSKYGCTKDCANILKNKLSDNVTIVDINNNNKIELSK
                     FDKIIIGSSIYVGSVSKKIQVLCNDNVELLNKKQVGIFLCCGFSEQADKYLKSNFPSS
                     LLESANAIGIFGSEARLEKMKFLDKLIMKAVSKGNYDSFRISQDNIDNFLINLNS"
     gene            complement(10812..11216)
                     /locus_tag="KR231_001600"
     CDS             complement(10812..11216)
                     /locus_tag="KR231_001600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FMN-binding protein"
                     /protein_id="HBH0003982.1"
                     /translation="MKIRNKATNKKKKYVKISIALFFVFICIIIVIVSNLKPENLVVK
                     DIDINNVKNGIYTGSADNNLVKATVSVEVNNGKIQNINILKHDHLLGKPAEKITTSII
                     KQQSLDVDAITSATYSSNTIRKAVENALRKGE"
     gene            complement(11191..11820)
                     /locus_tag="KR231_001601"
     CDS             complement(11191..11820)
                     /locus_tag="KR231_001601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBH0003983.1"
                     /translation="MSIKERRKNEKEEMKKKIMDASIEIINQHGYENLSIRKIATKIE
                     YSPTTIYLYYKDKAEIISDMTNKLYNTVESNAIDIMNNCSSLPIDKQIIEIMTSFIKT
                     LSSEPEMAKSIMYSRMNIIFASENTNNTPSNNGIKMLDKFLSIGIEQGIFKKNIDKSS
                     WMLISALLGFVLCVVENKLYSLHNFSQLIENFLDILVGGLYNENSQQGY"
     regulatory      12185..12228
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00522"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="PreQ1 riboswitch class I; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="preQ1"
                     /db_xref="RFAM:RF00522"
     gene            12329..13297
                     /locus_tag="KR231_001602"
     CDS             12329..13297
                     /locus_tag="KR231_001602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside hydrolase"
                     /protein_id="HBH0003984.1"
                     /translation="MEKRKVIIDCDPGIDDSLAILLALNSPELEVIGITTCCGNVPAN
                     IGAENALKTLQMCSSLNIPVYIGEEAPLKRKLVTAQDTHGEDGIGENFYQKVVGAKAK
                     NGAVDFIINTLYNHEKVSIIALAPLTNIAKALIKDKKAFENLDEFVSMGGAFRIHGNC
                     SPVAEFNYWVDPHGADYVYKNLSKKIHMVGLDVTRKIVLTPNIIEFINRLDKKMAKYI
                     TEITRFYIDFHWEQEGIIGCVINDPLAVAYFIDRSICKGFESYVEVVEDGIAMGQSIV
                     DSFNFYKKNPNAIVLNEVDEKKFMYMFLKRLFKGYEDIIDSVEGVI"
     gene            13299..13862
                     /locus_tag="KR231_001603"
     CDS             13299..13862
                     /locus_tag="KR231_001603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HBH0003985.1"
                     /translation="MKRKICVKTITLIAFGISINIIGAFIAMGLRLPVYLDSIGTIMI
                     ASLLGPKYAVVTGVFGSLISGITFDVYSLYFAPVQISTGLLAGIAFKKNFLRGLKTPL
                     GVLLFAIPTSIISSIISAFLFGGMTSSGSSYIVQILKVLGLGDVFSVFVTQVFTDYGD
                     KLLAVVLVNLGLNAVPKTLKVSLTGGK"
     gene            13870..14559
                     /locus_tag="KR231_001604"
     CDS             13870..14559
                     /locus_tag="KR231_001604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM protein"
                     /protein_id="HBH0003986.1"
                     /translation="MDRYSEITNKNQREIVLLKGFPCIWGKCSFCDYIDDNSNLEEEM
                     NKLNLKVLKNVTGKYGVLEVINSGSCFELPKDTLEKIKCIIKEKNIKKLFLESHWSYK
                     NRLKEMREYFEIPVVFKIGVETFDNDFRNNILNKNANFKTPQDVKEYFDSPCIMVGIK
                     GQTKEMIDKDIEIILNTFEKATVNVFINNSSSIKRDEELVKWFVSKYKFLDENPNIEV
                     LYNNTDFGVGD"
     gene            14686..15414
                     /locus_tag="KR231_001605"
     CDS             14686..15414
                     /locus_tag="KR231_001605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA alkylation repair protein"
                     /protein_id="HBH0003987.1"
                     /translation="MMFDRVKWNKLDYNELLEYMMSIQDIKYRDFNKKLIPGTENIIG
                     IRVPNLRKLSKEISQGNWKEFLEVAEDTYYEEVRLQGMVIGNINSNFEETLYYVKRFI
                     PKIDNWSVCDGFCSDLKSMKKYKENMYDILKKYVYSKNPWEIRFALVMFLIYYVDDKH
                     IKEIFEYCNNIQSEEYYVKMGMAWLLSICFIKCEEETFLYIKNNNLDDFTYNKMLQKI
                     IESNRVDLEKKNIIRSMKRKTRRC"
     gene            15428..16102
                     /locus_tag="KR231_001606"
     CDS             15428..16102
                     /locus_tag="KR231_001606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HBH0003988.1"
                     /translation="MNNNEDRIDKFLELQSKGFKFAEIAQNLKISQSTLRTFLNKKGY
                     KSEKGKYIFKDELNYNKSLDNRNLEEEKAKEYEKSKKNTISNRKKVSTKKKISNEKAL
                     SKSVEQIEFNDTGLKNAKPKQNIKPKKDRKINITQEDLDKLCEVYDWYLEVKDYNIKP
                     KKVSNKKDVHIDDEHIDELKTTRIRIDKEIWNDFERLCSNSNFEKHQILTQALKEFMK
                     KYKNLL"
     gene            16128..16964
                     /locus_tag="KR231_001607"
     CDS             16128..16964
                     /locus_tag="KR231_001607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0003989.1"
                     /translation="MNKIVKKSISLMIILTIFIFMLTACEKDEQPDSVDIQTEDKNEI
                     KIDEGNAKVLNIGKSEIINIDEGDKVDTSTKVENNSTFNISNVELIYNEYDENKKIIS
                     SDSKALLDMTLMPGKVAYIECGHKTFVKGVEVYAYEYEAEGKIVYVNLKENTINIRNN
                     NIKLENSSQYEVLSTSELKKVNESNEGITYQVKVKNSSSKDLGNIILKTAEVNENGEY
                     LTVNRVPSYKILKPSEETDIDILCSTKAKSVEIVGYTYDDIKEKANVDIDLKSHKVKI
                     DK"
     gene            16980..17651
                     /locus_tag="KR231_001608"
     CDS             16980..17651
                     /locus_tag="KR231_001608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBH0003990.1"
                     /translation="MKVLIVEDNKILLESVVEELSKHFETEKCEDGEEALYLVNQNIY
                     DLVILDLMLPNINGFDILKKMRVNNIDTPVLILTAKETLDDKVEAFTIGANDYLTKPF
                     YMEELVARVYAILRTNGKIKERNGLEFKSLYLDTLEKRVYIEKEEIKLQNKQFNLLEY
                     FVLNKGSILLKEQIYDRIWGIDSDATIEIVEVYVSNLRKKLSKYGYDKYIKTKRKVGY
                     IFDDK"
     gene            17641..18873
                     /locus_tag="KR231_001609"
     CDS             17641..18873
                     /locus_tag="KR231_001609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBH0003991.1"
                     /translation="MINKNVFTSTKNHLIKMYIIVVGSFLIIFSIFIYSYFRGLTYSG
                     IDSEINDELEYIVSQFKRTSFLNPIRLKDPKDMVYVYEDGRISYYTQNEYFDELLPDR
                     RLDKKNSFFKYTENGYTFRELNVDVGRYQIQIIRNIDSEMNSLRQLTSVLIIGILISV
                     IITYFVAVYLTRKALIPIETAWKNQAKFIQDASHELRTPITIVSSKLESMLKSPESTV
                     NDEVETIATAMKETRRLKKMITDLLSLTKEDSIVKVNLEEIDLEKLLEEISEDYIDIA
                     EFQEKRFVFNSKLKNKVIITDKNKLRQLILIFIDNAFKYTKLGDEIALELKEDIEDEV
                     TLLISDTGIGIKKEEIPLIFDRFFRSENVRNKDLEGSGIGLSIARMISLNLSIDINVT
                     SDVDIGTTFELSIPKKLK"
     gene            19023..19340
                     /gene="trxA"
                     /locus_tag="KR231_001610"
     CDS             19023..19340
                     /gene="trxA"
                     /locus_tag="KR231_001610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin"
                     /protein_id="HBH0003992.1"
                     /translation="MAKVINTSEFRSSVEGSKGVVVVDFFATWCGPCNMLGPVFAELG
                     EEMKDKARFVKVDIDESLEIAQQFNVSTVPTMIIFKDGKPVETLIGFMPKNKIEMQVK
                     SYL"
     gene            19357..20235
                     /locus_tag="KR231_001611"
     CDS             19357..20235
                     /locus_tag="KR231_001611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HBH0003993.1"
                     /translation="MRYDIAIIGSGPAGLSAAINAKIRNKTIIMFGNDNLSNKLVKAP
                     SIDNYLGFYDISGDELKDKFKSHIDSMDISIENKRINNIYAMGEYFTIMSGNDMYEAT
                     TVILATGVEYTRPIKGEEEFLGRGVGYCATCDAPLYRNKKVAVIGYNEESKEEANFLS
                     ELTSKTYFIPMYKKDNLMRSSDNLDDSIEVIHDRPVQIDGDKLVNKVSFKENHIEVDG
                     VFVIKDSTAPSALVPGIEIDGIHIKVDNNMKTSIDGCFAAGDCVGKPYSYIKAAGQGQ
                     IAALNAVYYLDKLKRA"
     gene            20505..20873
                     /locus_tag="KR231_001612"
     CDS             20505..20873
                     /locus_tag="KR231_001612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HBH0003994.1"
                     /translation="MENLVKIFKALSDETRLNILILVSKRNICQKGISKYLGISDSAV
                     SQHIKILKDVGIITGYKEGYYVLYHINKESFNICVDFINSMLSNSSESFIDVFDVNTI
                     HLGCSKECKSIKKCCKRREK"
     gene            20876..21247
                     /locus_tag="KR231_001613"
     CDS             20876..21247
                     /locus_tag="KR231_001613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NifB/NifX family molybdenum-iron cluster-binding
                     protein"
                     /protein_id="HBH0003995.1"
                     /translation="MKVCIPVEENKGLDSKPYGHFGSAPIFVVCDLESGEVKSLDNGD
                     LDHEHGKCQPLKALSGTAVDAVVVGGIGQGAIIKLNGMGIKVYRAEGDTISANLDLLK
                     NGKLVEFPSDHTCSHDGCGHH"
     gene            complement(21392..21847)
                     /locus_tag="KR231_001614"
     CDS             complement(21392..21847)
                     /locus_tag="KR231_001614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0003996.1"
                     /translation="MNINTVQGDSIEVLLRQLGATRISKVSSTLYFIKFDLGDGWEIS
                     YTYNINAKDQYFLQRIEPYPIGRGLFNDEYEIVSFISKDLKKFLNAKNSSNFKTFVEV
                     TRKVNSIIDNVEELFLNYNVDGDDLKTLNKELNDILNDIDYIEKHTKKI"
     gene            complement(21886..23151)
                     /locus_tag="KR231_001615"
     CDS             complement(21886..23151)
                     /locus_tag="KR231_001615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ArsB/NhaD family transporter"
                     /protein_id="HBH0003997.1"
                     /translation="MEFQQIIAICIFLIVMAAIITEKVNRSVAAVGGALLMIIFNILT
                     LDEGLSHIDFNTIGVLVGMMLFVAVVKNSGLFEYIAIWTAKKAKGDPWKIMICFAIIT
                     AILSAVLDNVTTVLLIGPMTIVITQILGLNPVPFLITQILASNIGGTATLIGDPPNIM
                     IGSAANLSFMDFVINLGPAVIVILAITIICFRFIYGKELVVNERAKNAILKLDEKKSV
                     KDKPLLIKSLILIAFILFGFMFHSTIHIDSSVVALTGASIMLLIGKQDVDEIMAGIEW
                     STILFFMGLFVVVGGLVEVGIINKLAQALIGLTEGHLVFTMLLILWLSAIVSSFLDNI
                     PFVATLIPLILTMQAEGIDVMPLWWATSLGACLGGNGTLIGASANVVLAGIGNKHGHP
                     ISFKEYFKIGFPLMIISIIISTVYLIIKF"
     gene            23621..25072
                     /locus_tag="KR231_001616"
     CDS             23621..25072
                     /locus_tag="KR231_001616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine:cation symporter family protein"
                     /protein_id="HBH0003998.1"
                     /translation="MDFFNGILTSINNAVVFVNNYLWSYILIIMLVVIGIYFTIKTNF
                     VQFRYFIEMFRLLGDGTANKNAKKEGKISSFQAFCISTSSRVGTGNIAGIAIAVVAGG
                     PGAVFWMWLIALIGSASSFVESTLAQIYKVKDGQAFRGGPAYYMEQGLNKKWMGILFS
                     ILITICYGFVFNAVQANTVSLAFNNAFGISKMAMGIGLGILTAIVIFGGVHRVAKVSE
                     IIVPVFAGLYILVALAIVVMNITEIPSVIALIVESAFDFKGMAIGTFMGVVMTGVKRG
                     LFSNEAGMGSAPNAAATAHVTHPVKQGLIQSLGVFTDTIIICSCTAFMVLLYSGYSSS
                     GATGIELAQEALTHHIGPVGNIFIAVCIFLFAFSSIVGNYYYGESNMEFMSGSKTKLN
                     VFRVFVVGMVLFGSLTQVDVVWNLADLFMALMAIINLIAIALLGKYAFIALKDYTSQK
                     KSGIKDPVFIADEIEGLEKVSEWHRELSEEHLG"
     gene            complement(25270..25911)
                     /locus_tag="KR231_001617"
     CDS             complement(25270..25911)
                     /locus_tag="KR231_001617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007491147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PAS domain-containing protein"
                     /protein_id="HBH0003999.1"
                     /translation="MTDNYIFDSYNNLVDGLSAYLGEGYEFILYKFNGVHYSINKIAN
                     GKYNTVKEGDIITDFDLALINKLENDADGDFISYFNRNKLGEPLKSTDIVIRGVDNKI
                     IGLLCIHFYLNTPLTRIIGSYIPEHNAMQSAPVLENIVEDTDEVILKSYQDAKVIVEN
                     DSNISSNDKNKSIVSILNESGIFKIKDSVVKVADLMGLSKNTIYMHLRNLNKN"
     gene            26385..27764
                     /locus_tag="KR231_001618"
     CDS             26385..27764
                     /locus_tag="KR231_001618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016290023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HBH0004000.1"
                     /translation="MAQDKIVVEILENIGGKENIKEVAHCMTRLRIKVCDSSQVNQEK
                     LKKIKGVLGLVLKGEQYQIVIGPNVSQVYNTLNEVIGIIPEKDSKKTISEGKQNSIAK
                     ILDTIAGIFNPIVPALAGAGLIKAILALLVASKFLSADSETYIILNTISDGVFSFLPF
                     MLAYSAAKIFKMNTYVAVAIAGAMLHPNFINLIQQGLTKISFIGIPMSLIQYNGSVFP
                     IVLTIWFASYIEKGVDKITPKALKIILVPALTILFAAPIALIIIGPIAQMLGNYIAGG
                     ASILFERGGIFAGLIYGGIYSFMVVTGLHHGMVPVLVDGITRYGFNYISPVSGSSNMA
                     QAGSAFGVWLKAKDKDLKAVAATATISALTGVTEPAIYGVNLRLKKPFLCAAIGGAAG
                     GGFAAYFQCKAFAMGGPSFLTLPMFIGEGGHVGLVAIAFTIAFIVSAIATYIVGFEEE
                     VTADSHANL"
     gene            27808..28542
                     /locus_tag="KR231_001619"
     CDS             27808..28542
                     /locus_tag="KR231_001619"
                     /EC_number="3.5.99.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010990049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosamine-6-phosphate deaminase"
                     /protein_id="HBH0004001.1"
                     /translation="MKIYLTKDYEEMSQVAAQMVLKYMYSNDNKRINLSITAGQTPKR
                     TYEILSEFVKNKPYFENVHYYNFDEIPIKGEKVGVTIRNLTNMYFREAQIPEERIHVL
                     DENNYQGFDRKIEADGGIDMVLMGLGWDGHFCGNLSGTVNSFDEETRAVSTYITDDMA
                     KLLTKSVGGNPEKLFDYYVTYGPKTIMHCKNIIMIVNGKHKAQILKQTLFGPLDLLCP
                     SSLLRLHPNFTLIVDEEAASEIKDLI"
     gene            28631..29830
                     /locus_tag="KR231_001620"
     CDS             28631..29830
                     /locus_tag="KR231_001620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006875852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HBH0004002.1"
                     /translation="MYNHMKKVFQGLEGGLFSSVEKADVGDSYQKLGEQGVSLMGWAD
                     PFFPDYCIPRHILDAATLAISSNMSTHYTAPVGNDLLKIEIAEKLKEVNNLDVDFKRN
                     ILITPGSDSGLYYSMLPFINEGDEVLIPTPCYPNNIQNTKLMGGVPIFVELKESDGYQ
                     IDITEFEKRLTNKTKLVVLTHPNNPTTTIFNKESLEKLAKFIIDNDLILICDQAFEDF
                     TFENELITPASLEGMFERTVTIFSTSKGMGLSGFRVAYMVCSDKLMDKYYGAAVTVLG
                     ATNTVAQMSTIEAFKDRSFMEDFERVFDKRRQEAYKIINEIPNVSMQMPESGFLGWIN
                     VSKLGTSSEIQKYLVDEAKVCINDGINYGPGGEGHLRIILGSYKDDSKVIGALNRIKD
                     ALIKKQQ"
     gene            29854..30336
                     /locus_tag="KR231_001621"
     CDS             29854..30336
                     /locus_tag="KR231_001621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015529974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HBH0004003.1"
                     /translation="MLSIFKSKKNDNKLKAFASGKVIPIEDVDDNVFSSKMLGDGIAI
                     YPTNEYVVAPCDAEVNIIMKDTKHAVGIKLFNGMEILFHVGIDTVSMNGEGFEIFVSP
                     GDKIKRGDKLISFNSKLIKEEGLQDVVIMVVTNSEQYKNIKYHIGLEAVIDDTIIAEI
                     "
     gene            complement(30654..31251)
                     /locus_tag="KR231_001622"
                     /pseudo
     CDS             complement(30654..31251)
                     /locus_tag="KR231_001622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816433.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(31495..31923)
                     /locus_tag="KR231_001623"
     CDS             complement(31495..31923)
                     /locus_tag="KR231_001623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0004004.1"
                     /translation="MKIHSIQNLTLDTRNLIKKYSLTLNEDLIWEFKHGKYHTIKYFT
                     HKFAVKESVLALLFNIHKLCYAKIKYFESSFSKYEPYKYSYQNEFVKCEMYDMNFMFH
                     KYSNIMIDLRNLQEIKTIEEFRLFCDYLESFEDNLQDLII"
     gene            complement(32324..32785)
                     /locus_tag="KR231_001624"
     CDS             complement(32324..32785)
                     /locus_tag="KR231_001624"
                     /EC_number="2.5.1.78"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6,7-dimethyl-8-ribityllumazine synthase"
                     /protein_id="HBH0004005.1"
                     /translation="MIYEGKLIGKDLKIGIINSRFNEFITSKLLSGAEDCLLRHDVSP
                     ENIEIVWVPGAFEIPLVAQKMAKSGKYDAIICLGCVIRGATSHYDYVCSEVSKGIAKV
                     SLDSELPVIFGIVTTENIEQAIERAGTKAGNKGYDCAMNALEMANLFKSLD"
     gene            complement(32890..34083)
                     /locus_tag="KR231_001625"
     CDS             complement(32890..34083)
                     /locus_tag="KR231_001625"
                     /EC_number="3.5.4.25"
                     /EC_number="4.1.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     3,4-dihydroxy-2-butanone-4-phosphate synthase/GTP
                     cyclohydrolase II"
                     /protein_id="HBH0004006.1"
                     /translation="MFNTIEEAIEDIKNGKMVIVVDDESRENEGDLLMAAEMATPESI
                     NFMATYGRGLICLPATEKKFKSLNIPLMVRENTDTFQTAFTVTIDGADTLTGISAYER
                     AETVKLFCDENSTSKDFKTPGHIFPLIAKTGGVLVRDGHTEASVDLARLAGFKEIGLI
                     CEIMKDDGTMARVDDLMIFKEKHNLKIITIKDLIEYRKINETTIEKVSSAFLPTKYGN
                     FEIIGYRDTYSNEEHIALTYGNINIENTLVRLHSECLTGDVFHSLKCDCGLQLESSMK
                     KIVENGSGVLIYMKQEGRGIGLLNKIKAYKLQEEGYDTVEANLMLGFEEDMRDFYMAA
                     QILKNLNIKSINLLSNNPDKINQLEKYGIKIENRIPINEEINDFNKLYLKTKKDKMGH
                     LLDII"
     gene            complement(34106..34771)
                     /locus_tag="KR231_001626"
     CDS             complement(34106..34771)
                     /locus_tag="KR231_001626"
                     /EC_number="2.5.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="riboflavin synthase"
                     /protein_id="HBH0004007.1"
                     /translation="MFTGIVEEVGILRKITANGKSGKVTILSNKILDGTNLGDSIAVN
                     GVCLTVSNLGKNEFTADVMMETIRSTNLGLLNANDKVNLERAMSLSSRFGGHIVTGHV
                     DGKGTICKFEKDENAVLVSIRPDKKLLSSMILKGSVAIDGVSLTISYLDDEIFKVSII
                     PHTKINTILLTKNVGDFVNLESDVIGKYVNNFMANNYKELNSNSSNHKSNIDKDFLFK
                     NGF"
     gene            complement(34805..35917)
                     /gene="ribD"
                     /locus_tag="KR231_001627"
     CDS             complement(34805..35917)
                     /gene="ribD"
                     /locus_tag="KR231_001627"
                     /EC_number="1.1.1.193"
                     /EC_number="3.5.4.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     diaminohydroxyphosphoribosylaminopyrimidine
                     deaminase/5-amino-6-(5-phosphoribosylamino)uracil
                     reductase RibD"
                     /protein_id="HBH0004008.1"
                     /translation="MNFVNQKEKDIYYMKKAIELAKNGEGFVNPNPLVGCVIVKDSNI
                     IGKGYHEKFGSNHAEVNAINSAKQSLKDSTLYVNLEPCSHYGKTPPCVDKIIQNKIKR
                     VVISTLDPNPLVCGNGVKKLKDNNIDVTVGILEDEARDLNEAFFYHIKNKRPLCIVKS
                     AVSLDGKIATKSLESKWISNESSRYLTHKYRNKYQSIMVGINTVLNDNPLLTCRLNQE
                     KVSHPTRIVIDTHLKLPLNSNLVKDKTSKTIVFTCCKESIKLSMLKENNVETIISPSK
                     NNLVDLEFVMYKLGELNIDSVLVEGGATLNDSLFRNKLVDKVKLFLSPKIIGGKDAPT
                     FVSGEGINHLSDSTQLTINNVTLIDGDILIESDVLN"
     regulatory      complement(36049..36170)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00050"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="FMN riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="flavin mononucleotide"
                     /db_xref="RFAM:RF00050"
     gene            36359..38841
                     /gene="recQ"
                     /locus_tag="KR231_001628"
                     /pseudo
     CDS             36359..38841
                     /gene="recQ"
                     /locus_tag="KR231_001628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729557.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase RecQ"
     regulatory      38930..39041
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            39183..40484
                     /gene="thiC"
                     /locus_tag="KR231_001629"
     CDS             39183..40484
                     /gene="thiC"
                     /locus_tag="KR231_001629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomethylpyrimidine synthase ThiC"
                     /protein_id="HBH0004009.1"
                     /translation="MNYTTQMDAARKGIITKEMEIVSQKEQVDVNELRELIANGQVVI
                     PANKNHKSLSAEGVGKNLRTKINVNLGISRDCKDIEKELEKVRVAIDMKAEAIMDLSN
                     YGKTREFREKVVEMSPAMIGSVPMYDAVGYLEKELKDITEEEFLNVIRQHAIDGVDFI
                     TIHAGLTRSVCQKIKNHERLTHIVSRGGSLLFAWMELNNKENPIYTNFDKILDICEEY
                     DVTLSLGDACRPGCIKDSTDGVQIQELVVLGELTKRAWERNVQVMIEGPGHMAIDEIE
                     ANVVLEKRLCHGAPFYVLGPLVTDIAPGYDHITSAIGGALACAKGVDFLCYVTPAEHL
                     RLPNLDDMKEGIIAAKIAAHAGDIAKNVKGAREWDNKMSKARADLDWCEMFRLAIDPE
                     KAKRYRDESTPTHEDSCTMCGKMCSMRTVKKILNNEELNLI"
     gene            40538..40732
                     /gene="thiS"
                     /locus_tag="KR231_001630"
     CDS             40538..40732
                     /gene="thiS"
                     /locus_tag="KR231_001630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfur carrier protein ThiS"
                     /protein_id="HBH0004010.1"
                     /translation="MKVNGKEIEFEKDLTVIDLLNKYNLKSDRVVVEVNLEIIEESNY
                     NTYVLKDEDIVELISFIGGG"
     gene            40725..41528
                     /gene="thiF"
                     /locus_tag="KR231_001631"
     CDS             40725..41528
                     /gene="thiF"
                     /locus_tag="KR231_001631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine biosynthesis protein ThiF"
                     /protein_id="HBH0004011.1"
                     /translation="MVKIKIFVNELLTDVEENTTAYKVRDSYNNKCDVLVLNGYPIKT
                     DMTLCENDKLTLIQKGVKPSLDELESLLIARHTPNIHNKLKKGKVAILGLGGLGSNIA
                     ISLARIGVGELLLIDYDVVEPSNLNRQQYFIDDIGKLKTDAMIENIKKINPFIKLNKR
                     DIFLNKNNMDTIKDSDLIIEAFDDASCKAQVCNYVLINLKDKYLIASSGMAGYYDSNI
                     ITTKKIKDRFYICGDFVNEAKFGEGLMAPRVAICANHMANLATQILIDM"
     gene            41591..42361
                     /locus_tag="KR231_001632"
     CDS             41591..42361
                     /locus_tag="KR231_001632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018592874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiazole synthase"
                     /protein_id="HBH0004012.1"
                     /translation="MDKLVLGGHEFNSRLLVGTGKYGSNNILPEVIKESGSEIITMAL
                     RRVDLDNKQENILTYIPKEMTILPNTSGATNAEEAVRIARISRKMGCGDFIKIEVISD
                     TRYLLPDNEETIKATKILADEGFIVLPYMTPDLYAGRRLIEANAAAVMPLGAPIGSNR
                     GLQMKEMIRIMIDELDIPIIVDAGIGKPSQAMEAMEMGADAVLVNTAIASAGDPVQMA
                     RAFKLAVEGGREAYIAKTGNVSEFANASSPLTGFLGNL"
     gene            42378..43481
                     /gene="thiH"
                     /locus_tag="KR231_001633"
     CDS             42378..43481
                     /gene="thiH"
                     /locus_tag="KR231_001633"
                     /EC_number="4.1.99.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-iminoacetate synthase ThiH"
                     /protein_id="HBH0004013.1"
                     /translation="MSFYDVIEKYRDFDFDGYLNNVTDNDVLRSLSKDKLEDFDILNL
                     LSKTAVKHLEDMAQKAHKLSVQYFGKTVCLYTPMYIANYCVNQCVYCSYNIKSGIKRK
                     KLTMDEIREEGEAISKEGFKHLLVLTGESSFHSSVEYIGEAIEILREKFPSIGIEVYP
                     MEVEEYKYIVDKGVEGLTVYQETYDEEIYKRVHIKGPKSNYKFRLDAPERGAKAGMRT
                     LSIGALLGLNDFRKETFFTILHGKYLKTKYPHIELSYSTPRMRPFKGCFEELVDISDT
                     DLVQAMVCMRLFDPHAAINISTRENLEMRSHIIPLGVTKLSAGVSTDVGGHSQDEHDT
                     AQFKINDESTVKDVEKMLNSIGYQHVFKDWERF"
     gene            43482..>43902
                     /locus_tag="KR231_001634"
     CDS             43482..>43902
                     /locus_tag="KR231_001634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine phosphate synthase"
                     /protein_id="HBH0004014.1"
                     /translation="MYLITNRKLCSEERYLEVIKESILSGVENIIIREKDLEYQELRK
                     LYMKIKTKINCIDFQEQISDESLKTNINQKECRNKFKVNFIINSNIEFFEKVDCQGIH
                     LPFKLFLNLIENKYNFNENKILGLSLHKVEEVDYLEKL"
BASE COUNT        16723 a         5018 c         7016 g        15145 t
ORIGIN      
        1 tatatatgtg taattaaaat gatttaggag gagaaatata ttggtaaatt gggaaataaa
       61 aaaattggct aaatctaaga gtatgtttat atctctaggc atattagtgt taatactaat
      121 gattagtatc tttattacgc ctgttttaga aacagaaagt tattatatag ataaagaaaa
      181 aggacgtata gaagatacga gaagtggtat cgacataggt aatgagaaat ttcaaaataa
      241 gattaatgtt ttaaagcagt tttcaaatca aacagataca ggtgaatttt ctaaaaaaat
      301 tgaattaatg tcaaagaaaa aacttgataa tctaagtgtg aatgaatata aggatattag
      361 tttttggaaa gtatttaact atagagttac aaattcactt ataaatgtag gaatgttaat
      421 cattatatct ataattatat ctaatattta cgtagatgaa gtcgttactt cggtaaaaga
      481 tatcatacta tcatcaaaag agaagaaaaa agcattaaat tctaaaatat ttgttgcttt
      541 attagttcca ttagtaattt attctgttta tttaatggga atatttatta taacttgtat
      601 gcaacaagga gtacctgtta atggagactt agaatctttt agaatagtag acaatgtagt
      661 tgcattgaaa actaatttaa gtataacaaa gtatgtaata ttaaatatag gcatagagct
      721 tttgatgttt gaaggatggg ccatgatagc catatttggg tcttttataa gtaagtcttc
      781 aatatcttca ataagttttt ttatatttat tatatctata actaagataa tgtcggtaat
      841 ccatatatta cctaaaaaat tactttcagt tgtatcaaat gtaaattatt atgatttgat
      901 atttggtttt aataaaataa taggaaatta tctaggtgat attatgatat ttaaagtgaa
      961 tatagacatt gtcaatatag caataggact tttgatggca atattgatag gtgctatgtc
     1021 attatgtttt ttagtaataa aatcagatta tataagtaga taaaagggga gttaagatga
     1081 ataaattaga aatagaaaat ctttcaaaga tatatggtaa aaaagtagca aacgacaaga
     1141 ttacagtaac tctagaaaat ggagtttatg gtcttctagg accaaatgga gcaggaaaat
     1201 ctacattaat gaaacaaata acaacgttga taaaacctga tgaaggtcag atactttata
     1261 atggtgagga tatatttaaa atggatgctg attatagaaa tattttagga tatttgccac
     1321 aagaatttgg agtttataaa aattttacag caaaagaatt tttacagtat attggagctt
     1381 taaaaggttt aaggggaaaa tatttaaata gtaagatagg agaattatta gatttagtag
     1441 gtctttatga tgtgagaaat aagtctatag gaaaattttc aggaggtatg aagaggagag
     1501 ctgggatagc acaagtttta ctaaacgacc ctaagataat agtccttgat gagccaacag
     1561 caggtcttga cccacaagaa agagctagat ttaggaattt aatagcaaaa atgtctagag
     1621 ataagataat aatactttct actcatataa tttccgatat agaatcagtt gcaaaggaaa
     1681 caataatgat taaagatggc aaactcctaa tgaaaggaac acacaaagac atattaagtc
     1741 acatggaaaa taaagtatat aatgttcaag ttaaaaatga atgtgaagtt gatgatatac
     1801 aatctaaata taaggttgta agtattcaaa gtgatattaa ttcaatagta cttagaattg
     1861 tttcagagga tattccaagc gaggataata tacaaccagt tcaagcaaaa ttcgaagatg
     1921 tatacatgtt ttattttgat ttagaagatg caagggaggt gtagtagaaa tgatgtattt
     1981 agttaaagct gaaatgataa aaatattaaa atcaaagagt gtttggataa tttggctgtt
     2041 tttaatattt tttggatttt ttctgattag aaagtttgat gttttagata cttatgcaga
     2101 tatattttac aagatagaag gctcaatacc tctaataggt ttgataatgt ttataataac
     2161 ttctggaaat tacattaaag aatatgattc taatatgaca ggtttaataa atacaactaa
     2221 aaagggaaaa aaatcagtag tattatcaaa actagtagct aatggattaa ttttatctat
     2281 tattaatatt tcttttatat tgttagtagg aattagaggt tttagttttt ttgattttaa
     2341 aaatttaaat gaatcgattc ataacttatg gtactttgga aatagtaatt taaatcttac
     2401 agtaatacaa atgtatataa ttgttatatt gactactatt tttgcttctt ttatatttgc
     2461 acaaataggc ttaacacttt catctatatt taaatcggct gtaattccat ttatactagg
     2521 tggattgata atggcaattc catactttag tgtaggtttt ataccagata aagctataaa
     2581 atttatgtca gtgactccaa attggattat gatgagccaa caaatggtta agtataatgt
     2641 accaagtatt ttgatagttt tttctatagt aatctcaatt atattaatga tagtgttaac
     2701 taaaataaca tatgaaaatt ttacatcaag caaaaggttt taactaaaaa taatagtaat
     2761 tttatttata ttttagttta attaaaaata agataaatga attttagata aaatatatgc
     2821 taatatatat gtaaattatt acaggaggtt gtttatggaa aatcgtgttt taataataga
     2881 tgatgaagta gaaatattga agcttttaga aactgtccta aaaaaagaag gccttaataa
     2941 tatatatact gcaaaaacta aaaaagaagg attagaatta tttaaaagta ttaatcctga
     3001 tttgattgta ttggatatta tgttaccaga tggcgaaggt tatgatattt gtaaagaaat
     3061 aagaaaaacc tccaattctc caataatatt tttatcagct aaaaccgaag aattagataa
     3121 gttacttgga ctagcgattg gaggagatga ttatgttaca aaacctttta gccctaagga
     3181 agtggctttt agagttaaag cgcatttgag aagattaagt tattttagtg atgctcaaaa
     3241 cgaaagtaaa aatctaaata ataatgaaga aaaaattata tcatttggcc catatatatt
     3301 aaatgaaagt agggcagaac ttataaaaga tggaaaatct ataggactgt ttgcaaagga
     3361 actaaaaatc ctatctttat ttgcacataa tcaaaatcaa attataagta aagaaaaact
     3421 atgggataaa gtgtggggag aagattatgt tggatttgac aatactataa tggttcatat
     3481 aagaaaaatt agggaaaaat tagaggataa tccttcaaaa cctgaatata ttctgacaat
     3541 aaaaggtctt ggatataaat tagcagtaaa ggaagattag aatatgaagt ggaagattac
     3601 tagaaatttt atatttacaa ttgtgtttgt agctatatca gtagtaatta taaatatcat
     3661 atctatattg tatgtgattt caactaatag cttttttaaa gttgtagatt ctggaaataa
     3721 tcctgaagaa tttgcacgtt cttttgaaaa agatttatat gaaaaagatg gagaatttaa
     3781 actatctaag attggagctg aaaaattaga aaaatcaaat tcctggatac aggttttaaa
     3841 tgatttagga gaggaagttt atggagtaaa tgtgccaaag gatactccaa aaaaatatac
     3901 accctttcaa atggtgaata attacaagta tatagaaaca aagtatgtta attttgtact
     3961 agaaaaatat ttaaacaaaa aacatttaaa cataatagta ggtataccta gtagagatat
     4021 atcaagaata attttaacct attctcaaaa taacattaaa aaaactttaa ataaagttat
     4081 cattataaca ctagtaattg atagcgtggt agctttaggt gtaggatatt tatttagtag
     4141 aaaacttaca aaaccaattt caagcgtact atggagtatt gagactatgg ctaatggaaa
     4201 ttatagttta tatcttaagg acagaggtat atatgaagaa gtttttaaaa atataaatat
     4261 gttagctgat actttaagag taaatgaagt tgagagaaaa gaaaatgaag agttgagaga
     4321 ggaatggctg gcaaatataa cacatgatat aaagacacct ctagcatcta tacaagggta
     4381 tgcagagata attaatgaca aagattatga gtttgaagaa gatgaaatac aagagtatac
     4441 agaaattata tataataagt ctaagtatat aaaagattta gttgatgatt taaatttatc
     4501 tactcgatta aaaaataata ctatagttct ggacaagaaa aaaataaatt tagtcagttt
     4561 agtcagagat ataataattg atattttaaa tgataataga tataaaaata ggaatattga
     4621 atttgaaagt aatgaagatt taattgaagt atatgtagat tcaatcttat tcagaagggc
     4681 tataaccaat cttatattta attcaatagt tcataatagc gaaggaactt tgataagtgt
     4741 agaaattgta aaaaaagata atatagaaat tataataaaa gataatggaa ttggaataag
     4801 caaaagtgat ttgaaacata tttttaaaaa atattataga ggtactaata caggtgagat
     4861 gcataaaggt tcaggtcttg gtatggctat ttctaaagaa ataatagaga ttcataaagg
     4921 taaaatttat gtaagtagtg aaattggaat aggaacaaaa attattatag agataaaaca
     4981 aaattaggag atatgatatg gattttttta aaaaaggtat aagtgggttt actattaaaa
     5041 ttttagcatt aatatttatg acatttgacc atatagcagc atttatgcca caaacaatgc
     5101 aaataccaat ttggtttcat tgggtaggca gaatatcagc accactgttt atattcatgg
     5161 ctgttgaagg attttatcac actagtaaca gaaaaaaata tataagtaga ttgtatattt
     5221 ggtctgttat tatggctata ggaaatcaaa taattaataa tgtattttca catccagaag
     5281 gagctataat tataaataac attttttcaa cattattttt aatagcgatt tatttacaag
     5341 caatagagtt cataaagaaa tttagaaaag agaaagaaat taaatatttt attataggat
     5401 tattgatgat aatcattcct ataattttag gaatatttac agtagcttta ctttttaaag
     5461 tcactaacag agttattgct ttatttatga ttttggtacc agtaccattt ttagtagaag
     5521 gtggaccaat ttggattata cttgggatta ttttttattt gtgtagaggt aaaaagttca
     5581 gtttgagtat ttgttatgtt ttaatgtgta tatttatatt tacaacaatg tcaaatggag
     5641 attatagttt aaaaaattct attttacaaa attaccaatg gatgatgatt gcttctctac
     5701 ctttaatgtt actttacaat ggagaaaaag ggaagagtat gaagtattta ttttatttat
     5761 actatccaat ccatgtatat atattgtata tcttaggaat atacttaata aatggttttt
     5821 gattgtaagt gatattttta atacaaaatg aacagtatga ggattgtttt aggtctatta
     5881 aaattgttat ttagatgaga tttgtagaat atttaaattt atgagcagaa attcagttat
     5941 tgtaatttca ataacattag aatataatat tataatttat ttagaaatat atgatgttat
     6001 acatggtttg gttattaatg taataataaa acagaggttt gatataaaat tcaatacctc
     6061 tgttttagtg ctttttatcc tacatttatg cttattttat ttataaatta gtgttttgtt
     6121 ttaattaata ttagtacatt ttttatttat tttataaaat tagtcataat tgtttcttca
     6181 tattgtggtt ctttaattcc agctttttta cctgctgata tacacttaag aagccatgcc
     6241 atgttttctc ctagagttcg catagtctgt aatccttctt catccttcat aacatcctct
     6301 ggagtaaagc catgtacctg gttccaatac tgtgatgata caataggcat attgctgatt
     6361 gaaaaatatt tatttagttg gtcaaatgtt gcacttgcac caccacgtct acatgacaca
     6421 actgaagcac ctaattttgt agccatgcga cttccagcta tgaaaaatag acggtcaaga
     6481 aaagaagtta attgaccagt tgcactagaa aagtaaacag gagaaccaat aataatacca
     6541 tcaatattat ccagatcttc aatcaattta ttaactttat catttcgaat acattttcca
     6601 gtttcaaaac aggatgcgca actaatacat cctgggattg tttctttacc taaatacagt
     6661 atttctgttt taatatcgtg tttactcaat actttagtaa tctcatttag tgctgtataa
     6721 gtacatccat attggtttgg gctaccgttt atcaataaaa ctttcattat aaatttcctc
     6781 caatgaattt tatttaatag attttctaag agatattatt ttttataaaa taggattttc
     6841 atgaatatta tcaatttata tagaaatgtc taatcttaga atcctattta aaataacttt
     6901 ttttttagta aatacacctc ctattataaa attgactttc aattattctt acactataat
     6961 tttattataa attattctaa aaacaagtac gcacattttt gttcaatact aaccaaaagg
     7021 agagtgtaat atatgagtat agactgtata tcaaatacag atttaagtga aacaggattt
     7081 agttatacac tttcactgat tagtggtaaa tataagatga taattcttta ctgtcttgta
     7141 gaatttgaag ttgtaagata taatgcatta aaacgttata taaatactat ctcctataaa
     7201 actttgagtt tatcattaaa agaattagaa gcagataact tgattattcg tactgaatat
     7261 cctcaaatac ctcctaaggt agaatatagt ctatcagaaa ggggaaaatc tctgattcca
     7321 attttagatg caatgtgtga gtggggagag aggaatagac cttaattttg tatctgtaga
     7381 taccataaaa agactgtgag taaaattgtt tgaataatct actcacagtc tatatttaaa
     7441 ttaatagtta gtatttttaa tttataaaaa tactaaaaaa tttattatga aatttcacca
     7501 ccaatttctt ttacatcttc tttatatata atacaagctt ctatagctaa ttctaagcct
     7561 tttactattt cttctaaaga catgaatggt gtattttttt tatctattac ttgtgaagtt
     7621 gtatatggga tgtgtataaa tccacccctt atattaggat atttcttgtc tatcatataa
     7681 agaattccat acatcacatg attgcaaaca aatgttcctg cagtgtttga aacactagct
     7741 ggaattttat tttcattcat atgttttacc atagctttta caggcaattt tgaaaaatat
     7801 gcaggttcac catcttcttt tataatagta tctataacct ggttaccctc attatctttt
     7861 attctaaaat catctatatt tatagcaact ctctcaggtg taatgtcaaa tctacctcca
     7921 gcttgtccaa ctgatattac tatatctgga ttgtgctctt gaatagcttt atctatagct
     7981 tcaacagatt ttgtcataac tgttggtata gttatcttta tgatttctgc accgtttata
     8041 ttattattga ccctttcaac tgcttcttga gctgggttta ttggttctcc accaaatggg
     8101 tcaaatcctg ttaacaaaat tttcattatt ttacctccta attatattaa aatcctaaaa
     8161 agtacattac taatatgtgg gctataatta ataccaaagc aactggagct tgatatttta
     8221 taacaatata atcattttta cattctagca aggctgctgg aactatatta aaattagcag
     8281 ccattggagt aagtagagtt ccacaatatc ctgctgttaa tgctaatgct ccaattatag
     8341 caggatttcc accttgagac aatacaaaag gaataccaat tcctgccgtt atgactgaaa
     8401 atgcggcaaa tgcatttccc attatcatgg taaatataac catacctaat acataagcta
     8461 taacaccaaa taatctgcta tcagcaggga ctacaccaga tatcatggtt gaaataactt
     8521 caccgactcc ggcttgagta aataaagctc ccaatgcaac taaaagttgt ggtaacatac
     8581 tagcaggtcc catttgttga agtaatcttg agccatcttg aactgatgta gcaggttttg
     8641 ccttagttat tataagggct gatattaatg caattattga acccacacct attgcaaatt
     8701 gagaagaatt atcaaaatta gaaaggctca tagctactac tactgcagca aatgctaata
     8761 ttaatgatgg tataaatatt ttatttttaa gtttgtctgc ttgttctttt ccaaaatttt
     8821 catctggttc ttcatacttt gcaaatacaa cttgtttaga aagtgttaat aaactagata
     8881 atattaatat tattcctatt atattggctg gaatcaatct accaaatatg aatggcagtg
     8941 atataagtat ccaaaataat gatgtaccat atttcttatt gttatttatg gtagtaaaag
     9001 acttatatgc tataacaatc attaaaaatc ccattagtgc gtaaaagatt tctaatgata
     9061 tgtttataaa attttgcatt tttattcctc ctaaataaaa ctatttttta tgacttttgt
     9121 ttaatttttt atcatataag gtaaactgga ttgtagccac tacaagtgct attactgcca
     9181 taatagtact agcctttacg atattaagtc cagttacatt gtatccaaat tgagtcagag
     9241 tagatgctat aagtaatact ccactactac ctgcaaataa gttttgacca taaaaatttc
     9301 catagttttc tgatgcagca gataatgcct ttatggcttc ttcatccgat tcttttagtt
     9361 catcactatt acttaaacca gcagcttgtg ccataggatt aacaagtggt cttacaaatt
     9421 gaggatgtcc actcattctt attgatagag caccagctat ttgtctagct atcatgtata
     9481 tagtaagtac ttttcctgtt gtaagtcttt ttaatttttc tattaaagaa acagctcttt
     9541 gttttaaacc atatctttct aatacaccga ttactggcaa tgttaatatg aataatgata
     9601 cacctctgtt tgagacaaaa gaatctccta aaattgtaaa aatttgatta aaatctaatc
     9661 ctgcaacaat tcctgttgcc actcctgcta ataatacagt aaataatgtg tcaattttaa
     9721 gtataaatcc aattacaact atcaatatac cgattagttt tatcataaat tgttctcctt
     9781 ccatttctat atgttttaat ttaaatttat ttaatggata aagttaaact ctttttatag
     9841 tatttgcgtt aataggacta ttattataaa atttaataaa aaatagggaa gatgttttaa
     9901 agtatcaaag taaataatgg ttgtgtatag gaatttgaat aacaaagatt atattttaag
     9961 ctaatatgaa ttgattttgt aagtctatag tttaagtata tgtcaatatt tgaaataggt
    10021 tttaaattag atattatatt ataaaaagag aatgtgccaa acatagagac aagtgtattt
    10081 ttcacttttg aaatgataaa aatatatttg atttcataca aaaagagagt gtctaatgaa
    10141 ttttttagtt cattagacac tctctttttg ttatgattaa taaaacatat ttgttatgat
    10201 taataaagca tatattaagt gctagtttca ttagatttca ctaagaaaaa taaaattttg
    10261 ataaagttta aagactattt tgagcaatat tacttataaa taaaagaatt tatcatagaa
    10321 ataattagtt ttattttagc tattaagatt tattaaaaaa ttatctatat tatcctgtga
    10381 tattctaaaa ctgtcataat taccttttga aacagccttc ataataagtt tatctaaaaa
    10441 tttcattttt tctaatcgag cttcactacc aaaaattcca atagcatttg cactttctaa
    10501 taaggatgat ggaaaatttg attttaaata tttatctgct tgttcagaaa agccacagca
    10561 aaggaaaatg ccaacttgtt ttttgtttaa taactctaca ttatcattac atagcacttg
    10621 tatttttttt gaaactgaac caacatatat agaacttcca ataataattt tatcaaattt
    10681 tgataactca attttattat tattattaat atcaacaata gtgacattat ctgatagttt
    10741 attttttagt atatttgcac agtcttttgt acaaccatat ttacttgaat atataataat
    10801 agtattcata attattctcc ctttcttaaa gcattttcta cagcttttcg tatagtatta
    10861 ctgctataag ttgcagaagt tatagcatcc acatctaaag actgttgttt aataatactt
    10921 gttgtaattt tttcagcagg tttacctaaa agatggtcgt gttttaagat attaatattt
    10981 tggattttac cattattaac ttcaacagac acagtagctt ttaccaagtt attatcagca
    11041 cttccagtat aaatgccatt tttaacatta ttaatatcta tatcttttac taccaagttt
    11101 tctggcttta agttgcttac aattacaata ataatgcata taaatacaaa gaatagagca
    11161 atagatattt ttacatattt tttcttttta ttagtagcct tgttgcgaat tttcattgta
    11221 aagtcctccc actaaaatat ctaagaaatt ttctataagt tgagaaaaat tatgtaaaga
    11281 atatagttta ttttcaacaa cacataaaac gaatcctaac aatgcactta taagcatcca
    11341 tgagctttta tctatatttt ttttgaatat tccttgttca attccaatgg aaaggaattt
    11401 atcaagcatt tttataccat tattgctagg cgtattgttt gtattttcag atgcaaatat
    11461 aatattcatt ctactataca tgatagattt tgccatctct ggttcactag aaagagtttt
    11521 tataaagcta gtcataattt ctatgatttg tttatctatt ggtagtgatg agcaattatt
    11581 cataatgtca atggcattac tttctactgt gttataaagt ttattggtca tatcgctgat
    11641 aatctctgct ttgtctttgt agtaaagata aattgtagtt ggagaatatt ctatttttgt
    11701 agcaattttt cttattgata aattttcata tccatgttgg tttataattt cgatgctagc
    11761 atccataatc tttttcttca tttcttcttt ttcattttta cgtctttctt tgatactcat
    11821 ataatcacct ctttgcttaa cggtgttaag ttaatttaca ctgttattgt ataatttaat
    11881 tttaatactg tcaataaatt attaaataat ataagttaat atatttttat ggataataaa
    11941 ttaatgttat taattgtaat atttaagata ttattgtata ataataatcg gtttaaatgc
    12001 gccacatctt attaaagttg gttcataatt ctaaataaac tttaataaga tacattaaaa
    12061 tataataaat tcttttatgc tataaaattt attttatagc tattaaatca gatgtttaaa
    12121 aattttttaa cagtctatag tttttaagag tctatagtaa gtagcctaaa aatatgattt
    12181 tacatctgta cttgttcgag aactccaagt ataaaaaact aaggaattat atagtggcag
    12241 tatataatta atacccttag acacaccttt ttgaaagtgg aaaaaagatg tgtagttctc
    12301 ctcgaccaca aatcaaggag gataaaaaat ggaaaagaga aaagtaataa ttgattgtga
    12361 cccaggaatt gatgattctt tggcaattct tctggcttta aactcaccag agctagaagt
    12421 aattggaatt accacatgtt gtggaaatgt tccagcaaat ataggtgcag aaaatgcact
    12481 aaaaacactt caaatgtgtt cttcactaaa tattccagta tatataggag aagaagcacc
    12541 actaaaaaga aaacttgtaa cagctcaaga tacacatgga gaagatggta ttggagaaaa
    12601 cttttatcaa aaggttgtag gagctaaagc aaaaaatgga gcagtggatt ttataataaa
    12661 tactttatat aatcatgaaa aagtatcaat aatagcactt gcaccactta caaatatagc
    12721 taaagcactt attaaagata agaaagcatt tgaaaatctc gatgagtttg tatctatggg
    12781 aggagcattt aggattcatg gaaattgctc tccagtagca gagtttaatt attgggtaga
    12841 cccacatgga gcagattatg tttacaagaa tttatctaaa aaaatccaca tggtaggttt
    12901 agatgtaact agaaaaattg tacttactcc taatattatt gagtttataa atagacttga
    12961 taagaagatg gcaaagtata taactgaaat aactagattt tatattgatt tccattggga
    13021 acaggaggga ataattggct gtgtgataaa tgaccctcta gcagtagcgt actttataga
    13081 tagaagtata tgtaaaggat ttgaatcata tgtagaagtt gtagaagatg gaatagctat
    13141 gggtcagtct atagtggatt ctttcaattt ctataaaaaa aatcctaatg caattgttct
    13201 aaatgaagtt gatgagaaga aatttatgta catgttttta aagaggcttt ttaaaggtta
    13261 tgaagacatt atagactctg tggaaggagt gatatagtgt gaaaagaaaa atatgtgtaa
    13321 aaactattac acttatagct tttggtattt ctataaatat aataggcgct tttatagcta
    13381 tgggattaag attacctgta tacttagatt caataggaac tataatgata gcttcacttt
    13441 taggacctaa atacgctgtt gttacaggtg tgtttggaag tttaataagt ggaattacgt
    13501 ttgatgtgta ttctctctat tttgcaccag ttcaaatatc aaccggatta cttgctggaa
    13561 tagcatttaa aaagaatttt ttaaggggtt taaaaactcc actaggagta cttttatttg
    13621 ccattccaac atctataata agttcaataa tttcagcatt tttatttgga ggtatgacct
    13681 cttcaggttc atcatatata gtgcaaatct tgaaagtgtt aggactgggg gatgttttta
    13741 gtgtgtttgt aacccaagta tttactgatt atggagataa gctgttagca gttgttttag
    13801 tgaatttagg attaaatgca gttccaaaaa ctttaaaggt atcattgact ggaggaaaat
    13861 agatagaaaa tggatagata tagtgagata acaaataaaa atcaaagaga aattgttctg
    13921 cttaaaggat ttccttgtat atggggaaag tgttcttttt gtgattatat agatgataat
    13981 tctaatttag aagaagagat gaataaatta aatctaaagg ttttaaaaaa cgtaactggg
    14041 aaatatggag ttcttgaagt cataaattct ggaagctgtt ttgaattacc taaggatact
    14101 ttagaaaaaa taaagtgtat tataaaagag aaaaatataa aaaaattatt tttagaaagt
    14161 cattggtctt acaaaaatag gcttaaggaa atgagagagt attttgaaat tcctgtggta
    14221 tttaaaattg gagttgaaac ctttgacaat gattttagaa ataatatttt aaataaaaat
    14281 gcaaatttta agactccaca agatgtaaaa gaatattttg attcaccttg tattatggtt
    14341 ggaataaaag gacaaacaaa agagatgata gataaagata tagagattat cctaaatact
    14401 tttgaaaaag cgacagtgaa tgtttttata aataattctt ctagtataaa aagagatgaa
    14461 gagttagtga aatggtttgt tagtaagtat aaattcttgg atgaaaatcc aaatatagaa
    14521 gttttataca ataatacaga ttttggtgta ggagattagc attaatttag tttaaattta
    14581 aaattgaaaa gtttcttatg tttttgaaaa agcttctaat agttagaagc tttttttgta
    14641 gagttttatg ttacaataag aaaaaaggaa ttaaggagca attaaatgat gtttgatagg
    14701 gtaaaatgga ataaattgga ttataatgaa cttttagaat atatgatgtc tatacaagat
    14761 ataaaatata gagattttaa taaaaagctt atacctggaa cagaaaatat aataggtatt
    14821 agagttccta atttaagaaa gttatcaaaa gaaataagcc aagggaattg gaaggaattt
    14881 ttagaagtag cagaggatac atactatgaa gaagttaggc tacaaggtat ggtaattggc
    14941 aatataaata gtaattttga agaaacttta tactatgtaa aaagatttat acctaaaatc
    15001 gataattggt cagtttgcga tggattttgt tctgatttaa agtctatgaa aaaatataaa
    15061 gaaaatatgt atgatatact taaaaaatat gtttattcaa agaatccatg ggaaattaga
    15121 tttgcattag ttatgttttt aatatattat gttgatgata aacatattaa agaaatattt
    15181 gaatactgta ataatataca aagtgaagaa tattatgtta aaatgggtat ggcatggttg
    15241 ctatcaattt gttttattaa atgtgaagag gaaacttttc tctatataaa aaataataat
    15301 ttagatgatt tcacttataa taaaatgcta caaaaaataa ttgaatcaaa tagagtagat
    15361 ttagaaaaga agaatataat aagaagtatg aaaagaaaga caagaagatg ttgacggagg
    15421 aatattaatg aataacaatg aagacagaat tgacaaattt ttagaacttc aaagcaaagg
    15481 atttaaattt gcagagatag ctcaaaatct aaagattagt caaagtactt taagaacttt
    15541 tttaaataaa aaaggatata agtcagaaaa aggtaaatac atatttaaag acgaattaaa
    15601 ttataataaa agtttggata atagaaactt ggaagaagag aaagctaagg agtatgaaaa
    15661 aagtaaaaag aatactataa gtaatagaaa aaaagtaagc accaaaaaaa agatttctaa
    15721 tgaaaaggct ttaagtaaaa gtgttgaaca aattgagttt aatgatacag gtttaaaaaa
    15781 tgcaaagcca aaacaaaata ttaagcctaa gaaagataga aaaataaata taactcaaga
    15841 agatttagat aagctttgtg aagtatatga ttggtattta gaagtaaaag attacaatat
    15901 aaagcctaaa aaagtatcta ataaaaaaga tgtacatata gatgatgaac acatagatga
    15961 attaaaaaca acaagaatac gtatagataa agaaatatgg aatgattttg aaagattatg
    16021 tagtaattcg aattttgaaa aacatcaaat acttacacag gcattgaaag aatttatgaa
    16081 aaagtataaa aatctactat aaaatactac tatatgaggt gcttaatatg aataaaatag
    16141 taaaaaaatc aatttctcta atgattatat taacaatatt tatttttatg ttgacagcat
    16201 gtgaaaaaga tgaacagcct gattcagttg atattcaaac agaagataaa aatgagataa
    16261 aaatagatga gggaaatgca aaagtattga atataggaaa atcagaaatt ataaatatag
    16321 atgaaggtga taaagtagat acatcaacaa aggtagaaaa taattcaaca tttaatatat
    16381 ccaatgttga attgatatat aatgaatatg atgagaataa aaaaattata tcttcggata
    16441 gtaaggcttt gttggacatg actttaatgc ctgggaaagt tgcttacata gaatgtgggc
    16501 ataaaacttt tgtaaagggt gtagaagttt atgcatatga atatgaggca gagggtaaga
    16561 ttgtgtatgt taatttaaaa gaaaatacta ttaatataag aaataataat attaagctag
    16621 aaaatagtag tcagtatgag gtgctatcta catcagaact taaaaaagta aatgaatcaa
    16681 atgagggaat tacgtatcaa gtaaaagtaa aaaattcatc atcaaaagat ttaggaaata
    16741 ttattcttaa gacagcagaa gttaatgaaa atggagaata tttaacagta aatcgtgtgc
    16801 catcatataa gattttaaag ccttcagaag agacagatat agatatattg tgttcaacaa
    16861 aggcaaaaag tgttgaaata gtgggatata cgtatgatga tataaaagaa aaagccaatg
    16921 tggatattga cttaaaatct cataaagtta agatagacaa ataaaggtag gggatactta
    16981 tgaaggtttt aatagttgaa gataataaga tacttttaga aagtgtagta gaagaactta
    17041 gcaagcattt tgaaactgaa aagtgtgaag atggagaaga agctttatac ttagtaaatc
    17101 aaaatatata tgatttagtc attttagact taatgcttcc taatataaat ggatttgata
    17161 tcctaaagaa aatgagagtt aataatatag atacacctgt acttatattg acagcaaaag
    17221 aaacattaga tgacaaagta gaagcattta ctataggagc taatgattat ttgacaaaac
    17281 ctttttatat ggaagagtta gtagctaggg tatacgctat attaaggact aatggaaaga
    17341 taaaagaaag aaacggatta gaatttaaat ctttatattt agatacacta gaaaaaagag
    17401 tgtatattga aaaagaagaa ataaaacttc aaaacaaaca gtttaacttg cttgagtatt
    17461 ttgtattaaa taaaggttca attttattaa aagagcagat ttatgataga atatggggaa
    17521 ttgattcaga tgcgactatt gaaatagtgg aagtatatgt aagtaatcta agaaaaaaac
    17581 taagtaaata tggatatgat aaatatatta aaactaaacg taaggtagga tatatattcg
    17641 atgataaata agaatgtatt taccagtact aaaaatcatt taataaaaat gtatattatt
    17701 gtagtaggta gttttttaat aatcttttct atatttatat actcatattt taggggactt
    17761 acatatagtg gaattgatag tgagataaat gatgaacttg aatatatagt ctctcaattt
    17821 aaaagaactt catttttgaa cccaataaga ctgaaagatc ctaaagatat ggtgtatgtg
    17881 tatgaagatg gaaggataag ttactatact caaaatgaat attttgatga gttacttcca
    17941 gatagaagac tagataaaaa aaattcgttt tttaaataca cagaaaatgg atatactttt
    18001 agagaattaa atgtagatgt aggtagatac caaatacaga taattagaaa tatagattct
    18061 gagatgaatt ctttaagaca gcttacatct gttcttataa ttggaatatt aatttctgta
    18121 ataattactt actttgtggc tgtatatctc actagaaaag ctttaattcc aatagaaaca
    18181 gcatggaaaa atcaagctaa gtttatacaa gatgcttctc atgaattaag aacaccaata
    18241 acaatagttt catcaaaatt agaaagtatg ttaaaatccc cagaaagtac agtaaatgat
    18301 gaagttgaaa caatagctac tgcaatgaag gaaactagaa gacttaaaaa aatgataact
    18361 gatttattgt ctcttactaa agaggactct attgttaaag ttaatttaga agaaatagat
    18421 ttagaaaagt tattggaaga aatatcagaa gactatattg acattgctga gtttcaggaa
    18481 aaaagattcg tgtttaattc taaacttaag aataaagtta taataacaga taaaaataaa
    18541 ttaagacagc ttatattaat tttcattgat aatgccttta agtatacaaa attgggtgat
    18601 gagatagcat tagaattgaa agaagatata gaggatgagg taactttact tataagtgac
    18661 actggtatag gcataaaaaa agaagagata cctcttatat ttgatagatt ttttagaagt
    18721 gaaaatgtaa gaaataaaga tttagaaggt tctggaatag gactttcaat agctcgcatg
    18781 attagtttaa acttatctat tgatataaat gtaacttctg atgtagatat tggaactaca
    18841 tttgaattgt caatacccaa aaagttaaaa taataaaaat ataaaaaatt gtttttagaa
    18901 atgaagaatg ggtatactaa ttagtataaa atataaaaag accttataaa agtaaattta
    18961 tatttataaa tttcatagta taattatata gggataataa agtttaatag gaggatttaa
    19021 aaatggcaaa agttataaat acatctgaat ttagaagtag tgttgaaggt agtaagggag
    19081 tagttgtagt tgatttcttt gcaacttggt gtggaccttg taacatgttg ggacctgtat
    19141 ttgcagaatt aggtgaagag atgaaggata aagctagatt tgtaaaagtt gatatagatg
    19201 agagcttaga aatagctcaa caattcaatg tatctacagt accaactatg attatattta
    19261 aagatggaaa accagtagaa actttaattg gattcatgcc aaagaacaaa attgaaatgc
    19321 aagtaaaatc atatttataa aaaatgggtg agtattatga gatatgatat agctataatc
    19381 ggcagtggtc cagctggatt gtctgctgct ataaatgcaa aaataagaaa taaaacaatt
    19441 atcatgtttg gtaatgataa tttaagtaat aagcttgtta aagctccttc aatagataat
    19501 tatttaggtt tttatgatat aagtggtgat gaattaaaag acaagtttaa atcacatata
    19561 gatagtatgg atatttcaat tgaaaataaa agaataaata atatttatgc tatgggagaa
    19621 tactttacaa taatgtctgg aaatgatatg tatgaagcta ctactgtaat ccttgcaact
    19681 ggggtagagt atactagacc aatcaagggt gaagaagaat ttctaggaag aggtgtgggc
    19741 tactgtgcta catgtgatgc accactttat agaaataaaa aggtagcagt tataggatat
    19801 aatgaagaat ctaaagaaga agcaaatttt ttaagtgaac tcacttcaaa gacttatttt
    19861 atacctatgt acaaaaaaga taatcttatg agaagttcag ataacctaga tgattctatt
    19921 gaagttatac atgacagacc agtacagata gatggagata aacttgtaaa caaagtatct
    19981 tttaaagaaa accacattga agttgatgga gtattcgtta taaaagatag tacagctcca
    20041 agtgcattgg ttcctggaat agagattgat ggcattcata ttaaagttga caataatatg
    20101 aagactagta tagatggatg ctttgctgct ggagattgtg ttggaaaacc atattcttat
    20161 ataaaagcag ctggtcaagg gcaaatagca gctttaaatg ctgtttacta tttagataaa
    20221 ttaaagaggg cttaatattt atattgatta actttttaaa gatatttata aaaaactgtc
    20281 ttgaaataat tttattattt caagacagtt ttttattttt aagttattaa taaaagtatt
    20341 ttaaaatcta tatgtaatta cttttattaa taaaactcaa agttatatta gtaaaaattg
    20401 gaattattta taatatactc caaaatttaa aaataatggt tgaaaaatct aattaagagt
    20461 actataattt aattaagtaa ttacttaatc aaaacgaggt acttatggaa aacttggtta
    20521 aaatatttaa agcattgagt gatgaaacta gacttaacat acttatatta gtatccaaga
    20581 gaaatatatg tcaaaagggg atttctaaat atctagggat ttcagattct gctgtttcac
    20641 aacatataaa aatattaaaa gatgttggga taataacagg atataaagaa ggatactatg
    20701 ttttatatca tattaataaa gaatcattta atatatgtgt agattttata aattctatgt
    20761 taagtaattc tagtgaaagc tttatagatg tatttgatgt aaatacaata catctaggat
    20821 gcagtaaaga atgtaaatct ataaaaaaat gttgtaagag aagggagaaa taataatgaa
    20881 agtatgtata ccagtagagg agaataaagg attggatagt aaaccatatg gacattttgg
    20941 ttctgctcca atttttgttg tgtgtgattt agaaagtgga gaagttaaat ctttagataa
    21001 tggagattta gatcatgaac atggaaaatg tcaaccatta aaagcattgt cagggacagc
    21061 tgtagatgca gtagttgttg gaggaatagg acaaggagct ataattaaat taaatggaat
    21121 gggaataaaa gtttacagag cagaaggtga tactataagt gctaatttag acttacttaa
    21181 aaatggaaaa ttagtagaat ttccatcaga ccatacttgc tcacatgacg gatgtggaca
    21241 tcattaaaaa aaaacagctg atgaaatata tacttcatca gctatttttt cttttaataa
    21301 atacgatttt attcttttaa aaccaaaatt tagattttta tattttttgt agtatcctta
    21361 ataatatttc aagtttacaa gtttactact tttagatttt ttttgtatgt ttttctatat
    21421 agtcaatatc atttaatatg tcattgagtt ctttattaag tgtttttaaa tcatcaccat
    21481 ctacattgta gtttaaaaat agttcctcta cattatcaat gatagaattg acttttctag
    21541 taacttcaac aaatgtctta aagttactac tatttttagc atttagaaat ttttttaaat
    21601 cctttgatat aaatgatact atttcatatt catcattaaa tagacctcta ccaataggat
    21661 atggttcaat tctctgtaaa aaatattggt ctttagcatt aatattataa gtataagata
    21721 tttcccaacc gtctcctaaa tcaaacttga taaaatataa tgtactactt acttttgata
    21781 ttcttgtggc accaagctgt cttaaaagaa cttcaatcga atcaccttga acagtattaa
    21841 tattcatata tacacatccc ctttagtatt attatactat attttttaaa attttataat
    21901 taaataaaca gtagatataa taatagatat aatcataagt ggaaaaccta ttttgaaata
    21961 ctccttaaaa gagataggat gaccgtgttt attacctata cctgctagta caacattagc
    22021 agatgctcct attagtgttc catttcctcc aagacaagct ccaagagatg ttgcccacca
    22081 tagtggcatt acatcaatac cttcagcttg catagtcaaa ataagaggaa ttagtgttgc
    22141 aacaaatgga atattatcta agaaagaaga gactatagct gacaaccata atatcaacaa
    22201 cattgtaaat acaagatgtc cttctgtaag tccaatcaat gcttgagcca atttgtttat
    22261 tatcccaact tctactaatc caccaactac tacaaataat cccataaaga ataaaattgt
    22321 agaccattca atacctgcca taatttcatc tacatcttgt tttcctatta aaagcattat
    22381 agatgctcct gtcagtgcta caacagaaga atctatgtgg attgtactgt gaaacataaa
    22441 accaaaaagt atgaatgcta ttaatataag gctttttata agtagaggtt tatctttaac
    22501 agattttttt tcatctagtt ttaatattgc atttttagct ctttcattca caacaagttc
    22561 ttttccataa ataaatctaa agcatattat agttatagca agtattacta taacagcagg
    22621 acctaaattt attacaaaat ccataaaact aagattggca gcactaccaa tcataatatt
    22681 tggagggtct cctataagag tagctgttcc tcctatattt gaagctaaaa tctgtgttat
    22741 taaaaatgga actggattaa gtcctaatat ttgtgtaata actatagtca ttggtccaat
    22801 aagtaagacg gttgtaacat tatctaatac agctgataaa atagctgtta taatagcaaa
    22861 gcaaatcatt atcttccatg ggtcaccctt agctttcttt gcagtccaga tagctatata
    22921 ttcaaataac cccgagtttt tgacaacagc tacaaatagc atcataccaa ctaatacacc
    22981 aatagtattg aaatctatat ggcttaatcc ttcatcaagt gtaagtatat tgaatattat
    23041 cattaatagt gcaccaccaa cagctgctac ggatctgttt accttttctg taataatagc
    23101 tgccataact attaaaaata tacatatagc tattatttgt tgaaattcca taatataagt
    23161 acctccattt gtattatttt gtgcctaatg ctagtactat atatagtatt acttttttat
    23221 tgttttttca atggatgtat gaaagtatat tatttaacaa agtttttgaa aaattgacag
    23281 aatttaaaga aaatttttgt tatttaaata aattttaaaa ttattccatt gataataata
    23341 ttaaacgaca aacgaaaaaa tatacccttt aaactagaat ttattgtatc taataacaat
    23401 tataaaatat taaatatatc tatattataa aaacaataaa aaaaggtttg atttgaatat
    23461 aaaactgcaa tatattaaaa aaattattca ttttaaacct tgtaatttga ttttataaat
    23521 attataatta aattaatgaa tttttaacaa ggaattattc atttttttga ttttaagatt
    23581 tattgagaaa acaaaactaa ataggggggt aattaatata atggattttt tcaatggtat
    23641 tttaacgagt attaacaatg cagtagtatt tgtaaacaat tacttatggt cgtatatctt
    23701 aattataatg ttagttgtaa ttggtattta ctttactatt aaaacaaatt ttgtacaatt
    23761 cagatatttt atagaaatgt ttagacttct gggtgatggt acagcgaata aaaatgcaaa
    23821 aaaggaagga aaaatctctt catttcaagc attttgtata agtacatctt caagagttgg
    23881 aactggaaat atagctggaa tagcaattgc agtggtagca ggaggacctg gtgctgtatt
    23941 ttggatgtgg cttatagcat taattggttc tgcatcaagc tttgttgaga gtacattagc
    24001 tcagatttac aaagtgaaag atggtcaagc ttttagaggt ggaccagcgt attatatgga
    24061 acaaggtcta aataaaaaat ggatgggtat tttattctca atacttataa ctatatgtta
    24121 tggttttgta tttaatgcag ttcaagcaaa tactgtttca cttgcattta ataatgcatt
    24181 tggaataagt aaaatggcta tgggaatagg tcttggaatt ttaactgcaa tagttatttt
    24241 tggtggagtg catagagttg caaaagtttc tgaaataata gttcctgtat ttgcaggatt
    24301 atatatatta gttgctttgg ctatagttgt aatgaatata acagagatac caagtgttat
    24361 agcattgata gttgaaagtg catttgattt taaaggaatg gcgattggta catttatggg
    24421 agttgtaatg actggagtga agagaggtct attttctaat gaagcaggta tgggtagtgc
    24481 tcctaatgct gctgcaacag cacatgtaac tcatcctgta aaacaaggtt taattcaatc
    24541 tttaggtgtt tttacagata ctataataat atgtagttgt acagcattca tggtattatt
    24601 atattcaggt tatagtagta gtggagcaac tggaattgaa ttagctcaag aagctttaac
    24661 tcatcatata ggaccagttg gaaatatatt tatagcagtt tgtatattct tgtttgcatt
    24721 tagttctata gttggtaatt actattatgg tgaatcaaat atggagttta tgagtggaag
    24781 taagactaaa cttaatgtat ttagagtttt tgttgtaggt atggttttat ttggttcact
    24841 tactcaagtg gatgtagttt ggaatcttgc agacttattt atggcattga tggcgataat
    24901 aaacttaata gcaatagcac ttttaggaaa atatgcattt attgctttaa aagattatac
    24961 aagtcaaaaa aaatcaggaa taaaagaccc tgtgtttatt gcagatgaaa tagaaggcct
    25021 agaaaaggta tcagagtggc atagggaatt atctgaggaa catttaggat aaaaaatagt
    25081 ataaaattat aaaaccattt tgaaagacta gagtatgtat atactttata tgaatataat
    25141 attgaattaa tttatattac tggaattttt aattccagta atattttttt aattacaagg
    25201 atattatgat gacttaaaga ctgtggaaaa ctctttttta gttttcatta ttaatattaa
    25261 ttgacaaatt tagtttttat ttaaatttct taagtgcata taaatcgtat tttttgataa
    25321 tcccattaag tctgcaactt taacaacaga atccttaatt ttaaaaatac cactttcatt
    25381 taaaatagaa acaatagatt tatttttatc attgctagat atattagaat cattttcaac
    25441 aattaccttt gcatcttggt atgattttaa aattacttca tcagtatctt ctacgatatt
    25501 ttctaaaaca ggagcacttt gcatagcatt atgttccgga atatatgaac caattattct
    25561 tgttagtggt gtattaagat aaaaatgtat gcagagtaga ccgattattt tattatcaac
    25621 tccccttatc actatatctg ttgattttaa aggttcacct agtttgtttc tattaaaata
    25681 actgataaaa tctccatcag catcattttc gagtttatta atgagtgcca aatcaaaatc
    25741 agttataata tctccttctt ttacagtatt atatttacca ttagctattt tatttattga
    25801 atagtgtact ccattaaatt tatataaaat aaactcgtat ccttctccta aatacgcaga
    25861 taatccatcc actagattgt tataagaatc gaaaatatag ttatcagtca tgttaaaagt
    25921 catatgttac ctcctaagaa atatcttaat atcatattaa catataaaat gaatttaata
    25981 aaatatattt cagtgaaata ataaatataa tgaaaaaaaa actattgact gaaaaatatt
    26041 tcagtgatat tattaaaata cagtaaggca aacgtattat tgacagaata tataaaatgt
    26101 taaaaatagt atctaggaat taaacaaatt aaaggactag tgatttgaat ttttttagta
    26161 taatatgtga cttccaatta atatttatta aacaccaata aaattgtaaa tatgcttaat
    26221 gatatacttt agcgatgaag tgaaaatatt ttatttttat gattaaccta taggaattaa
    26281 tttagcatac tgtttagcta gtaaatctaa ataaatttta gctttagctg atatcatgtt
    26341 gaataaagtt tctattggat tttgtataac aaaggagtgg ggagatggca caagataaaa
    26401 ttgtggttga aattttagaa aacattggtg gtaaggaaaa tattaaggaa gtagcacatt
    26461 gtatgactag actgagaata aaggtatgtg atagttctca ggtaaatcag gaaaaactaa
    26521 agaaaataaa aggtgtacta ggtcttgtat taaaaggtga gcaatatcaa attgttatag
    26581 gtcctaatgt atcacaagtg tataatactc ttaatgaagt tataggaatt atacctgaga
    26641 aggatagtaa aaaaacaata tctgaaggta aacaaaatag tattgcaaaa atattagata
    26701 ctattgcagg tatttttaat cctatagttc cagcattagc gggtgcaggt ctaataaaag
    26761 ctatattagc attactagta gcatcaaagt ttttatctgc agatagtgaa acctatataa
    26821 tattaaatac aatatctgat ggtgtatttt catttttacc atttatgtta gcttactcag
    26881 cagctaaaat atttaaaatg aatacttatg ttgctgtagc aatagcagga gcaatgctac
    26941 atcctaattt cattaattta attcaacaag gcttaactaa aatatctttt atcggtattc
    27001 cgatgtcact aatccagtat aacggaagtg tatttccgat agtactaact atttggtttg
    27061 catcgtatat agaaaaagga gtagataaaa taacaccaaa ggcacttaag ataatattag
    27121 tacctgcatt gactatttta tttgcagctc ctatagcatt aattattatt ggaccaatag
    27181 ctcaaatgct aggaaactat atagccggtg gagcaagtat cctatttgaa agaggaggaa
    27241 tatttgcagg gttaatttac ggaggaattt attcattcat ggtagtaaca ggattacatc
    27301 atggtatggt tcctgtatta gtagatggaa taacaagata tggatttaac tatataagtc
    27361 ctgtgtcagg tagttcaaat atggctcaag caggatctgc atttggagta tggttaaaag
    27421 caaaagataa agatttgaag gctgtagcag ctacagctac catatcagca ttaactggag
    27481 ttaccgaacc tgcaatatat ggtgttaatt taagattaaa gaaaccgttt ttatgcgctg
    27541 ctataggtgg tgcagcagga ggtggatttg ctgcatattt ccaatgtaaa gcatttgcta
    27601 tgggaggtcc atcgttttta actcttccta tgtttatagg agaaggtgga catgtaggat
    27661 tggtagcaat agcatttaca atagcattta tagtatctgc aatagctacc tatatagtag
    27721 gatttgaaga agaggtaaca gcagattcac acgctaactt ataataaaga gaaattattt
    27781 aacatatcaa aaaggagatt aattactatg aaaatttatt taactaaaga ttatgaagaa
    27841 atgagccaag tggcagcaca aatggtgtta aagtatatgt acagcaatga taataaaaga
    27901 ataaaccttt ctataacagc aggtcaaaca ccaaaaagaa catacgaaat attaagtgaa
    27961 tttgttaaga ataaacctta ttttgaaaat gtacattatt ataactttga tgaaatacca
    28021 ataaaaggcg aaaaagttgg agttactata agaaatttaa ctaatatgta ctttagagaa
    28081 gctcaaatac cagaagaaag aatacatgtg ttagatgaaa ataattatca aggctttgat
    28141 agaaagatag aagccgatgg tggaatagac atggtattaa tgggattagg ttgggatgga
    28201 cacttctgtg gaaatcttag tggtacagtc aactcttttg atgaagagac aagagctgtt
    28261 tcaacttata taacagatga tatggctaaa ctattaacaa aatctgtagg tggaaatcca
    28321 gaaaaattat ttgattacta tgtgacatat ggacctaaaa caataatgca ttgtaaaaat
    28381 ataataatga tagtaaacgg aaaacacaaa gctcaaatat taaagcaaac actatttgga
    28441 ccattagatt tattatgtcc atcatcttta ttgagattac atcctaactt cacattaata
    28501 gtagatgaag aagcagcatc tgaaataaaa gatttaatat aaataagtaa ggaattaaaa
    28561 ttaaaaatga atttaggtgc aaagtaatat tttattttgc acctttgctt taataaaaag
    28621 gagaataaaa atgtataatc atatgaaaaa agtattccaa ggattagagg gtgggttatt
    28681 ttcaagtgta gagaaagctg atgtaggcga ttcttatcaa aaattaggtg agcagggtgt
    28741 aagtttaatg ggatgggcag atccattttt cccagattac tgtataccta gacatatatt
    28801 agatgcagct acattagcga tatcaagtaa tatgtcaact cattatacag cgcctgtagg
    28861 taatgactta ttaaaaattg agatagcaga aaaattaaaa gaagtaaata atttagatgt
    28921 tgattttaaa agaaatatat taataactcc tgggtcagac tcagggcttt attactcaat
    28981 gttaccgttt ataaatgaag gggatgaggt tcttatacca acaccatgct atccaaataa
    29041 tatacaaaat actaaattaa tgggaggagt tcctatattt gtagagttaa aggaatcaga
    29101 tggatatcaa atagatataa cagaatttga gaagagatta actaataaga cgaagttagt
    29161 agttcttact catcctaata atccaacaac tacaatattt aataaagaat ctttagaaaa
    29221 attagctaaa tttattatag acaatgattt aatattaata tgtgatcaag catttgaaga
    29281 ttttactttt gaaaatgaat taataacacc agcttcatta gaaggtatgt ttgaaagaac
    29341 agtaacaata ttttcaacat caaaaggtat gggattaagt ggatttagag ttgcatatat
    29401 ggtatgcagc gataaattaa tggacaaata ctatggagca gcagtgacag tattaggtgc
    29461 tactaataca gtagctcaaa tgtcaacgat tgaagcattt aaagatagaa gctttatgga
    29521 ggattttgaa agagtttttg ataaaagaag gcaagaagca tataagataa tcaatgaaat
    29581 acctaatgta tctatgcaga tgcctgagtc cggattttta ggttggataa atgtatcaaa
    29641 gcttggaaca tcatcagaaa tacaaaagta tctagttgac gaggctaaag tttgtattaa
    29701 tgatggaatt aattatggtc caggaggaga agggcatttg agaataattt taggaagcta
    29761 taaagacgat agtaaggtaa ttggtgcatt aaatagaata aaagatgctt taattaaaaa
    29821 gcaacaataa ataaaaaata attggagtgg agtatgttat caatatttaa gagtaaaaaa
    29881 aatgacaaca agcttaaggc atttgcatca gggaaagtaa ttcctataga agatgttgat
    29941 gataatgttt tttcatctaa aatgttaggt gatggaatcg ctatttatcc aactaatgaa
    30001 tatgttgtag ccccttgtga tgcagaagta aatataataa tgaaagatac taaacatgca
    30061 gttggaatta aattatttaa tggtatggaa atcttatttc atgttggaat agatactgta
    30121 tctatgaatg gagaaggttt tgagatattt gtttcaccag gtgacaagat aaaaagaggt
    30181 gataaattaa tatcttttaa tagtaaatta ataaaagaag aagggttaca agatgtagtt
    30241 ataatggtag ttactaattc agaacagtat aaaaatataa aatatcatat tggactggag
    30301 gcagtaatcg atgatactat tattgcagaa atttaaaaac agttatttaa gtaaatactt
    30361 agataattta gatatagtta aaattaaatc cttaaaatca aattatttaa tttttgtgta
    30421 attttaacta taaagccgat taataatata aagtatacta aataatatgg ttattatgat
    30481 tgttactgac aaagcctaag tagatataac aatttgctct aattgagtat tgctatatct
    30541 acttgttttt atatttaaaa taaaagagtc tgcattgaaa agataattct gatgagagta
    30601 aatagggtat ttaataatag tttaattctg acttatcaag atgaacctat tcatatacct
    30661 aaaacatctt taacaccttc taaattcata caaatagctg tataggctgc cttattgatt
    30721 atttttccgt caatttttac tttgtagtga acagcatata taaatattat cgaatagatt
    30781 gtatcaagag ctctattttg ctattcatta gctaaagata gtactctgtc agttattttt
    30841 gaaactaatg catgagatat atcaattccg taaatattat ttaaatgtat gatatatatc
    30901 gcgagtcgac attccttttg agtacatgcc aattacttgg ttctctattc cagaaatttc
    30961 attttcgtaa ttttgaataa ccctaggctg gaaatcatcc ctagggatat ttaattttac
    31021 ctctccaaaa tctgatttaa cattcttagc tctatatcca tttcttgaat ttgatgttgc
    31081 tttactttgg ttatcatatc tctcgtacat taaatgatct tcaatctctg actctaacat
    31141 tttgtgaatt gtgcttgcga ataaatcttt taacatctct tggatgtctt tagtattttt
    31201 tacatcatac tcttgaacta agtgttttaa tatttaattt ttgttgtaca taaaaaatgt
    31261 gtacctccta ttttggtaat tagatttaat atcttgactt ttaggagaat acacatttta
    31321 ttttacagac cctcttttct agaaaagttt ttatgaaaat tgtgatataa attattaata
    31381 aaaaataatt ttatatttat tttattatgt aatttagttt tattaaaaat tttttattat
    31441 tggatataga ttatctatta taaattttat ctttaagttt attctcctaa aatactatat
    31501 aattaaatcc tgtaaattat cttcaaagct ttctaggtaa tcacaaaata atctaaattc
    31561 ttctatggtt ttaatttctt gtaaatttct caaatctatc attatattac tatatttatg
    31621 aaacataaaa ttcatatcat acatttcaca tttaacaaat tcattttgat aactatattt
    31681 ataaggttcg tattttgaaa aactcgactc aaaatatttt attttagcat aacataattt
    31741 gtgtatgttg aacaaaagtg caagaacaga ctccttaact gcaaacttat gtgtaaagta
    31801 ttttatcgtg tggtatttac catgtttaaa ctcccaaatt aaatcctcat ttaaagtaag
    31861 agaatatttt tttataaggt tacgcgtatc tagtgttaaa ttttgtattg aatgtatttt
    31921 cataatttat tctcctcata aatatttaat aagtattaaa ttatagtgtt ttattattaa
    31981 ttgttcttaa ttatattgta tggtaaatta aaaaagtaat aaaatagata attaatatac
    32041 tagtaatata tgctataaat aaaaacaata gctaaaatag taatatatat gtttttatga
    32101 tattttatgt ttagggttat atttgtaatt attttaagct tctaaaagta gatttgatgg
    32161 ataacgtata attttagaag gatatgcaat ttgtttgata agaacgtaca tatgattaaa
    32221 ttaaaaatat taagtaccaa aaagaagaaa gatagtttct ccctttggta cttaatattt
    32281 tgtatccttt acactaattt ttaatattta ttaatgatat tatttaatct agagacttaa
    32341 ataaatttgc catttctagc gcattcatag cacaatcata acctttattt ccagcttttg
    32401 tacctgctct ttcaatagct tgttcaatat tttctgtagt tacgattcca aatataacag
    32461 gtaattcact gtctaaagat actttggcta tccctttaga gacttcacta catacataat
    32521 cataatgaga agtagcccct cttataacac agcctaaaca gattatagca tcatacttac
    32581 cacttttagc cattttttga gcaacaagag gaatctcaaa agctccaggt acccaaacta
    32641 tttctatatt ttctggagaa acgtcatgtc ttaaaagaca gtcttcagct cctgataaaa
    32701 gttttgatgt tataaattca ttaaaacgag aatttattat acctattttt aaatcttttc
    32761 caataagttt tccttcatat atcattttta cttcctccaa ttttatttat gttatagatt
    32821 tatatttata aatatcttta atttaattat aaaaaactac ttagtagaaa aatatcatca
    32881 tataatcatt tatataatat ctaaaagatg tcccatttta tcttttttag tttttaaata
    32941 tagcttatta aagtcattaa tttcttcatt aatagggatt ctattttcga tttttattcc
    33001 atatttctct aattgattta ttttatctgg gttattactt aaaagattta tactttttat
    33061 gtttaaattt tttaatattt gagcagccat atagaaatct ctcatatctt cttcaaatcc
    33121 aagcattaaa tttgcttcaa cagtatcgta accttcttct tgaagtttat aagccttaat
    33181 tttatttaaa agaccaatac ctctaccttc ttgcttcata taaattaaaa ctccacttcc
    33241 attttccaca attttcttca tagaagattc tagctgtaat ccacaatcac attttagaga
    33301 gtggaacaca tctcctgtta aacattcaga atgaagtcta actagagtat tttctatatt
    33361 tatatttcca taagtaaggg caatgtgttc ttcatttgaa taagtatctc tatatcctat
    33421 gatttcaaaa tttccatatt ttgtcggaag gaaagcacta gatacttttt ctatagtagt
    33481 ttcatttatt ttgcggtatt ctataaggtc ttttatagtg atgattttta aattatgctt
    33541 ttctttgaaa atcattaaat catcaactct tgccattgta ccatcatctt tcattatttc
    33601 acagataaga ccaatctctt taaaacctgc aagtctagca aggtctactg aggcttctgt
    33661 atgtccatcc ctgacaagaa ctccaccagt ttttgctatt aaaggaaaga tgtgaccagg
    33721 cgttttgaaa tctttacttg tagaattttc atcacagaat aattttacag tttcagctct
    33781 ttcatatgca gatataccag ttagagtatc tgctccatct atagtaacag taaaggctgt
    33841 ttgaaatgta tctgtatttt ctctaaccat aagaggtata ttaagacttt taaatttttt
    33901 ttcagtggca ggtagacaaa ttagacctct accatatgta gccataaaat ttattgattc
    33961 aggagtagcc atttcagctg ccatcaataa atctccttca ttctctctac tttcatcatc
    34021 aactacgatt accattttcc cattttttat atcttcaata gcttcttcaa tagtattaaa
    34081 catgtaattc actcctttat tatttttaaa aaccattttt aaataaaaaa tctttatcta
    34141 tatttgattt atggttacta ctattagaat ttaattcctt gtagttatta gccataaaat
    34201 tattaacata ctttccaatt acatcgcttt ctaaattaac gaaatctcca acattctttg
    34261 tcaagagaat agtgttaatt ttagtatgag gtataataga aaccttaaat atttcatcat
    34321 ctaaatatga tatagttaaa cttacaccat caatagcaac agaacctttg agtatcattg
    34381 aggataaaag ttttttatca ggtcgtatac ttactaaaac tgcattttca tctttttcaa
    34441 atttgcagat agttccttta ccatcaacat gacctgttac tatatgacca ccaaatcttg
    34501 aagaaagact catagctctt tcaagattta ccttgtcatt tgcatttaat aaacctaaat
    34561 ttgtggaacg aattgtctcc atcataacat cggctgtaaa ttcatttttt ccgaggtttg
    34621 aaacagttag acaaactcca tttacggcta tactatctcc aagatttgtg ccatctaata
    34681 ttttatttga tagtatggtt acttttccac tcttaccatt agcagtaatt tttctaagta
    34741 ttccaacttc ttctactatg ccagtaaaca tcctaacctc ctatatgaat gtattaacaa
    34801 aaatttaatt taaaacatct gattctataa gaatatcgcc atctatcaaa gttacattat
    34861 tgattgttaa ctgtgttgaa tctgacaaat gatttattcc ttctccagaa acgaatgtag
    34921 gtgcatcttt accacctata atcttgggtg atagaaataa tttgacttta tcaactaact
    34981 tatttctaaa gagactgtca ttgagagtag caccaccttc aactagaaca gaatcaatgt
    35041 ttaactctcc taatttatac attacaaact ccaaatctac taagttgttt tttgaaggag
    35101 aaattattgt ttcaacatta ttttctttta acatagataa ttttatactt tctttgcaac
    35161 atgtgaaaac tatagtttta ctggttttat ctttaaccaa attactatta agtggcaact
    35221 ttaggtgtgt atctattact attcttgtag gatgagacac tttttcttga ttgagcctac
    35281 aagttagtaa aggattatcg ttcaaaactg tatttatgcc aaccattata ctttggtatt
    35341 tatttctgta tttatgagtt agataccttg atgattcatt agatatccat tttgattcta
    35401 gtgattttgt ggcaatttta ccatctagac ttactgctga ttttacaata caaagaggtc
    35461 ttttgttttt tatatgataa aaaaatgcct catttaaatc tcttgcttca tcttctaata
    35521 ttcccacagt aacatcaata ttgttatctt ttaatttttt tactccatta ccacaaacaa
    35581 gtggatttgg gtctaatgta gatattacaa ctctcttaat cttattttgt ataattttat
    35641 ctacacaagg aggcgttttc ccataatgag aacatggttc taagtttaca taaagagtag
    35701 agtcttttag actttgttta gcactgttta tagcatttac ttcagcatga ttagagccaa
    35761 atttctcatg atatcctttg cctattatat tactatcttt aacaattaca catccaacta
    35821 atggatttgg atttacaaag ccttctccat ttttagccaa ttcaatagct tttttcatat
    35881 aataaatatc tttttctttt tgattcacaa aattcacaat atgtacacct cctgtttaat
    35941 tggataattt ttaaacaaaa aaccctgaga attaactcag ggtttagaat aatctacaat
    36001 aaatgtttaa taaatgtaga acaaaattgc tctacaaaaa cactcattaa atatcttctt
    36061 ccatccagac tttactgtcg gctttggaat ttaaccaaat caaccaagtt ttacattggc
    36121 tcgcgggcta taccgccgat tgggaatttc accctacccc gaagattaag tattaaattt
    36181 atatttagaa tgtatcataa attattttac tttgcaaact atttttttaa aaaatatatg
    36241 ttaatatata atatagaatg tctataaact ttgaaatacc acgattgtga atataaaaat
    36301 aaaaatttga acataatcag gaaagaagtc taattaattt aaattaggag agtaatatat
    36361 gaataaaaaa cttttagaaa tactatcaaa atactatgga tatacaagtt ttagaaaagg
    36421 tcaggaatct ataataaatt ctatcttaag cgaaaaagat gtgctagcta ttatgccaac
    36481 aggaggggga aaatcaatat gttatcaaat tccagctttg attttagatg gaatgacaat
    36541 agtaatttct ccacttatat cacttatgaa agaccaagta gatgccttaa agactatggg
    36601 aattagtgct gcttttataa atagttcatt aagtagcaaa gaatttaatg aaatattaaa
    36661 taatattaga aaaaataatt ataaaatact ctatattgct ccagagagat tagatgcaca
    36721 agagtttatt gagctaataa ataataacaa tgtaagtcaa gttgcgatag atgaagcaca
    36781 ttgtgtatct caatgggggc atgattttag gttgagttat agaaggattt ctgattttat
    36841 aaaaaatttg cctaaaagac ctatagttac agcatttact gcaacagctt cagaagaggt
    36901 aagaactgat ataataaatt tactgtgttt agaaaatcca gattattata taactggatt
    36961 tgatagagag aatttatcaa taaatatagt aaaatcatct agtaaaaata agtatatttt
    37021 agattatatt caaaatcata aaaatgagtc tggaattata tatgttgcaa ctagaaagga
    37081 agttgaaaat atatataatg gtttatctaa gagaaatata tctgtatcaa aatatcatgc
    37141 aggtttatct aaaaatgaaa gaagtaaaaa tcaagaagat tttataaatg ataatgtgga
    37201 tataatggta gcaacaaatg catttggaat gggtattgat aaacctaata taagatgggt
    37261 tatacattac aatatgcctc aaagtataga aaactactat caagaaatag gtagagctgg
    37321 tagggatgga gaaaaaagtg agtgtgtact tttattttct ccaggagatg tacatataca
    37381 aaaatattta attgatattg gagttgaaaa tcctgaaaga aaattatttc agcataagaa
    37441 gcttcaatac atgattgact tagtttacag taattcatgc tatagaaaga caatattgag
    37501 ttattttgga gaaaattata tagacaattg caataattgt agcaattgtt tagtagaggg
    37561 tgaaatagta gataaaacta tagatgcaca aaaagtcatt tcatgtgtag ctagaatgaa
    37621 aagaagttat ggtgttacta ctattgtaga tgtgcttaga ggttctaaga ataaaaagat
    37681 tttacagctt ggattaaata ctttgtctac atataacatt atgagagatt attctagtga
    37741 agacttaaag aattttgtaa atacattggt ttctcatggt tttttagatt tagttgagac
    37801 tctaggcaat ggaaatagag gtagttttcc tactataaga ttaaatgaga tgtctatgaa
    37861 agttttaaaa ggtgaagtga aagtagagtt taaagaaatt gttatgacaa aatcattgga
    37921 agtagaggat gagttatata atgctttaag agaacttaga cattcaattg caagtgaaga
    37981 aaggatagct ccatatatgg tatttggaga tggtacactt agagccatgt ctagtagtta
    38041 tccaattaat aaagaagaaa tgctagatat ctctggagta ggagaaatta aataccaaaa
    38101 atatggtaga gattttgaag cagtaattaa agaatatgtc gaaaaaataa tataaataaa
    38161 aaaatagatg aaaaaaatgt cgattcaaag aacgttaata gtgatttctt agaggttaat
    38221 acagataaag ttttatatga aaaactgtta gtcattagag aagaatatgc aacaaaggaa
    38281 aaattacctg catatatgat tttagccaat aaggctttga aagaaataag tggaagatat
    38341 ccacttgatg aagaacaatt aaaagatatt tctggcatag gtggagtaaa atttgaaaaa
    38401 tatggagcta gtattttggc agaggttaat aaatatgtaa aagaaaataa tattaatgtt
    38461 atttgggaga aaaagggcaa aaggaagtta atattagatg gagaaagtag aaaaaataat
    38521 gaaatagcat tagatttgct aaatcaagga aaagatatac aaagtatcag tcaagaaata
    38581 gaagtttcac tgtcaaccat tattggatat gtgcatgact atgtaaagga tggacatagt
    38641 atatcatttg aattaggact agaaaatttt tataatgaag ataaaaagaa gatgatttta
    38701 gaagtttgcg aaaaagttgg ctatgataat ttaaataaca taaaaagaaa acttccagat
    38761 tcaataaagt atgaaaatat aagagctgtg atacttgact cttatcttga aaacttaaaa
    38821 aataatatta tagcagagta atttttaact taataaaaaa taaaatttgt attattgtgt
    38881 tgaactaata attttgctgt gttatactga atttgtaaaa ataatgaaaa attagagcta
    38941 ggggcgctag aattggctag ctgagagata aagccgtaac ttacaaaccc taataacctg
    39001 atcaagataa tgcttgcgaa gggaagcttt ttaatataat tttattatat aaataggcaa
    39061 attattcaat gttaggagaa atttgtctaa gtgtatatac gattataaga gtgctttcca
    39121 aacgaggaaa agcacttttt ttattttcaa aaactataac tttaatcttg gaggattgta
    39181 atatgaacta tacaacacaa atggatgctg ctagaaaagg cataataact aaagaaatgg
    39241 aaatcgtttc tcaaaaagaa caggtagatg taaatgaatt aagagaatta atagcaaatg
    39301 gacaagttgt tataccagct aataaaaatc ataaatcttt aagtgcagaa ggtgtaggta
    39361 aaaatttaag aacaaaaata aatgtaaatc taggaatttc aagagattgt aaggatatag
    39421 aaaaagaact tgaaaaagtt agagtagcaa tagacatgaa agctgaagct ataatggatt
    39481 taagtaatta tggcaaaact agagaattta gagaaaaggt tgttgaaatg tcacctgcaa
    39541 tgataggttc agtacctatg tatgatgcag taggatattt ggaaaaagaa ttaaaagata
    39601 taacagaaga agagttttta aatgtaataa gacaacatgc tattgatgga gtagacttta
    39661 ttactataca tgcaggtctt acaagaagtg tttgccaaaa aataaaaaat catgagagat
    39721 tgactcatat agtatctcgt ggaggttctt tattgtttgc atggatggaa ttaaataata
    39781 aggaaaatcc tatttatact aattttgata aaatattgga tatatgtgaa gaatatgatg
    39841 ttacattgag tttaggagat gcttgtagac caggttgtat aaaagattct actgatggtg
    39901 ttcaaattca agaacttgta gtattaggtg aacttactaa aagagcatgg gaaagaaatg
    39961 tacaagtaat gatagaaggt cctggacaca tggctattga tgaaatagaa gcaaatgtag
    40021 tattagaaaa gagattatgc catggagcac ctttttatgt tcttggacca ttggttacag
    40081 atatagcacc aggttatgac catataacaa gtgcaatagg aggagcttta gcatgtgcta
    40141 aaggagtaga ttttttatgt tatgtaactc cagcagaaca tttaagattg cctaatttag
    40201 atgatatgaa agagggtata atagctgcaa agatagctgc tcatgcagga gatatagcta
    40261 aaaatgttaa aggtgctcgt gaatgggata ataagatgag taaagctaga gctgatttag
    40321 actggtgtga gatgtttaga cttgcaatag accctgaaaa agctaagaga tacagagatg
    40381 aatcaactcc tactcatgag gatagttgta ctatgtgtgg aaaaatgtgc tcaatgagaa
    40441 cagttaagaa aatattaaac aatgaggaac ttaatctaat ataatttttg gctagtatga
    40501 ctggaataaa aataagctga aaagaggagg tgatttagtg aaggttaatg ggaaggaaat
    40561 tgaatttgaa aaagatttga ctgttataga tttattaaat aaatataatt taaaaagtga
    40621 tagagttgta gttgaagtga atttagagat aattgaagaa tctaactaca atacatatgt
    40681 attaaaagac gaggacattg tagagcttat tagctttatt ggaggtggtt aaaataaaaa
    40741 tatttgtaaa tgaattatta acagatgttg aggaaaatac aactgcttat aaagttagag
    40801 atagctataa caataaatgt gatgtattgg tgttaaatgg atatccaatt aaaacagata
    40861 tgaccctttg tgaaaatgat aaattaacac ttatacaaaa aggagttaag ccatcacttg
    40921 atgaattgga aagcttgttg attgctagac atactccaaa tatacataat aaattaaaaa
    40981 aagggaaagt tgctatattg ggattggggg gacttggttc caatatagct atctctttag
    41041 ctagaatagg agtgggagaa cttttactta tagattatga tgttgtagaa ccatctaatt
    41101 taaatagaca gcagtatttt atagatgata taggaaaact aaaaactgat gccatgatag
    41161 aaaatataaa aaaaataaat ccatttataa aattaaataa acgagatatt tttttaaaca
    41221 agaacaatat ggatactatt aaggattcag atttaataat tgaggccttt gatgatgctt
    41281 catgtaaagc acaggtatgt aattatgtat taataaattt aaaagataaa tatttaatag
    41341 catcatctgg tatggcaggt tactatgatt caaatataat aactactaag aagataaaag
    41401 acaggtttta tatatgtggg gattttgtga atgaagctaa atttggtgaa gggcttatgg
    41461 ctccaagggt tgccatctgc gcaaatcata tggcaaattt ggcaacgcaa atacttatag
    41521 atatgtaaat attaaaatta gatataaaaa agattgaata ttaaaaaaat ttaacgtgga
    41581 gggaaataat atggataaat tggtacttgg tggacatgaa tttaatagca gattattggt
    41641 tggaacaggt aaatatggtt caaataatat attgcctgag gtaataaaag aaagtggaag
    41701 tgaaataata acaatggcac ttagaagagt ggatttagac aataaacaag aaaacatatt
    41761 aacgtatatt ccaaaagaga tgacaatact tccaaataca tcaggagcta ctaatgcaga
    41821 agaagctgta agaatagcta gaatatctag aaaaatggga tgtggagatt ttataaaaat
    41881 agaagtaata tcagatacta gatatttact tcctgataat gaagaaacta taaaagctac
    41941 aaagatactt gctgatgagg ggtttatagt tcttccatat atgacaccag acctttatgc
    42001 tggaagaaga cttatagaag ctaatgcagc ggcagttatg ccacttggag ctccaattgg
    42061 ttcaaataga ggtcttcaaa tgaaagaaat gataagaata atgatagatg agttggatat
    42121 accaataata gtagatgcag gtattggaaa accatctcaa gctatggagg ctatggaaat
    42181 gggagctgat gcagtacttg tcaacactgc tatagcttca gcaggagacc ctgtacaaat
    42241 ggctagagca tttaaattag ctgtagaagg tggaagagaa gcatatattg caaaaacagg
    42301 aaatgtgtca gaatttgcaa atgcatcttc tcctttaaca ggttttttag gcaatttata
    42361 gaaagtggtg attggtgatg agtttttatg atgtaataga aaaatatagg gattttgatt
    42421 ttgatggata tttaaataat gttactgata atgatgtttt aagaagttta tcaaaagaca
    42481 agcttgaaga ttttgatata ttaaatttgc tttctaaaac tgcagtaaaa catttagaag
    42541 atatggcaca aaaagcacat aaattaagtg ttcaatactt tggtaaaaca gtatgtttat
    42601 atacaccaat gtatatagca aattattgtg ttaatcaatg tgtttattgt agctataata
    42661 taaagagtgg aataaaaaga aaaaaattaa ctatggatga aattagagaa gagggagaag
    42721 caatttcaaa agaaggtttc aaacatctac ttgttttgac tggagaaagt agttttcact
    42781 caagtgtaga atatataggt gaggctatag aaatattaag agagaaattt ccctctatag
    42841 gtatagaagt ttatccaatg gaagtagaag aatataagta cattgtagat aaaggtgttg
    42901 aaggattaac agtatatcaa gaaacttatg acgaggaaat atataagaga gtacatataa
    42961 aaggcccaaa atcaaattat aaatttagac tagatgctcc tgaaagaggg gcaaaagcag
    43021 gtatgaggac tttatcaata ggtgcacttt tagggctaaa tgattttaga aaagaaactt
    43081 tttttacaat attgcatggg aaatacttaa aaacgaaata tcctcatatt gagctttcat
    43141 attcaacacc aagaatgaga ccttttaaag ggtgttttga ggaattggta gatataagtg
    43201 atactgattt agttcaagct atggtatgta tgagattatt tgaccctcat gcagctataa
    43261 atatatccac tagagaaaat ttagaaatga gaagtcatat aataccttta ggagtaacta
    43321 aattgagtgc aggtgtatct actgatgtag gaggtcattc tcaagatgaa catgatactg
    43381 ctcaatttaa gataaatgat gaaagtactg ttaaagatgt ggagaaaatg ctaaactcaa
    43441 ttggttatca gcatgtgttt aaagattggg aaagatttta aatgtatctg ataacaaaca
    43501 gaaaattatg tagtgaggaa cgatatttag aagttattaa agagtctata ttgagtggtg
    43561 tagaaaatat aataataaga gaaaaggatt tagaatatca agagctaaga aaattatata
    43621 tgaaaataaa aactaaaatc aattgtatag attttcaaga gcaaatatca gatgaaagtt
    43681 tgaaaactaa tataaatcaa aaagagtgta gaaataaatt caaggttaat tttataataa
    43741 atagtaacat tgaatttttt gaaaaagtgg attgtcaagg tatccatctt ccttttaaat
    43801 tattcttgaa tttaattgaa aataagtata attttaatga aaataaaata ctaggattat
    43861 ctttacataa agtagaggaa gtagattatt tagaaaaatt aa
//
LOCUS       DAEPHU010000028        42399 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 01A10CD0081
            SAMN05941466-rid12468953.denovo.028, whole genome shotgun sequence.
ACCESSION   DAEPHU010000028 DAEPHU010000000
VERSION     DAEPHU010000028.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941466
            Sequence Read Archive: SRR6291087
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 42399)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 42399)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068158.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 22:43:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,892
            CDSs (total)                      :: 3,805
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 87
            rRNAs                             :: 8, 1, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 55
            CDSs (without protein)            :: 55
            Pseudo Genes (ambiguous residues) :: 0 of 55
            Pseudo Genes (frameshifted)       :: 21 of 55
            Pseudo Genes (incomplete)         :: 28 of 55
            Pseudo Genes (internal stop)      :: 16 of 55
            Pseudo Genes (multiple problems)  :: 8 of 55
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..42399
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941466-rid12468953.denovo.028"
                     /strain="01A10CD0081"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            complement(45..710)
                     /locus_tag="KR231_001635"
     CDS             complement(45..710)
                     /locus_tag="KR231_001635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0004015.1"
                     /translation="MKGNIVQYNFADIEEEVYSLDYAIAWNTDEENVNIIPFTNKFCK
                     ESIESFCLGKINNFVEILNEGFVENHHYVHLDKMISVPKKKVNLVYQQDTHGYLLRDD
                     NDNLIPAKITSEQSKSISSKMELFCAGEEKCLINILLKADPSYILDVDSIKDKNILNL
                     GYESIDRYKEYNFDDDKILIFFINKKRYSVIMKKTNNSDNDLVSRNNAIKELFTNKAG
                     NLN"
     gene            1054..2484
                     /locus_tag="KR231_001636"
     CDS             1054..2484
                     /locus_tag="KR231_001636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4116 domain-containing protein"
                     /protein_id="HBH0004016.1"
                     /translation="MDIKNKIKSIFLPEKNDYLDDEEFEYDIENNEEDLKEDNKVHLN
                     DLSRVKYDYRELKDIENQTEEMCLLAVKQDGTIIEFVKDKTYKVCMEAVKQTYKSLKY
                     ITNQNEDICIEAVKQNYRALYYINNKTENVLIEAIKNASTYDVMEVFKFVEEQTEDVC
                     LAFIERASKNDVAEILKGIKEQTPAICLEAVKKDGKSLAYVKEQSNSICLEAVKENYS
                     ALSCVKEQTEEICIEAVKQNDFALYYVNEQTEKICMEAVKRSYMALQYVNKQTEEICL
                     EAVRIDGRALQYVKEQTEEICLESVRQNGKVLQYVKKQTENICIEAVRGSFEELEIKE
                     ILSYVKIPTERIFVEAVKQNGKILKYVENQTELICLEAVRENYNALAYVKEQTEKICL
                     EAVNQSYEALKYVKEQTEEVCLKAVKQDYRMLKYVNNQTEKICLEAVKQNYRALEFVD
                     NQTEKVCLEAVKQNRKALQYVKQKQS"
     gene            2852..3430
                     /locus_tag="KR231_001637"
     CDS             2852..3430
                     /locus_tag="KR231_001637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory gene regulator B family protein"
                     /protein_id="HBH0004017.1"
                     /translation="MFKRYAEKMTSVLICNNMIDNNESKVYSYGFEILIAFIVNITTM
                     LFIGFLFGKFTYVLFFLMCYCPIRQFSGGYHADNYFRCLLTFIFIILSTILIIENINI
                     DLFKNIIMIIASVSWVGICVLCPIEHRSNPISDREKLVYKKTAIFISTVVLLITILSL
                     SLSIFVDYFTYSAFAMFWIFVMLVLGKLKAKV"
     gene            3460..3606
                     /locus_tag="KR231_001638"
     CDS             3460..3606
                     /locus_tag="KR231_001638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cyclic lactone autoinducer peptide"
                     /protein_id="HBH0004018.1"
                     /translation="MKKFIVRFMKFASSLALSTAILSANSTCPWIIHQPKVPKEISNL
                     KKTN"
     gene            3911..5290
                     /gene="scfB"
                     /locus_tag="KR231_001639"
     CDS             3911..5290
                     /gene="scfB"
                     /locus_tag="KR231_001639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioether cross-link-forming SCIFF peptide
                     maturase"
                     /protein_id="HBH0004019.1"
                     /translation="MSMIHKFSMNGYNIVLDVNGGAVHVLDDVAYDLLDFYKEKSKEE
                     ILEILKSKYQEEKINEAYEEILNLEKEGLLYTEDTYQYHPSFVHREPVVKALCLNVAH
                     DCNLKCKYCFAAQGDFGGEKELMSFEVGKAAIDYLIANSGSRKNLEIDFFGGEPLMNF
                     EVVKQLVDYGRSVEKDYNKNIRFTITTNGVLLNDEIIDYINENMHNVVLSLDGRKEVN
                     DNMRPTLNDKGSYDITLPRFKKLVEKRAKDKYYYIRGTFTRDNLDFSKDVMHFADLGF
                     KLTSVEPVVGDESNPYALREEDLPKIFEEYEKFAVEYADRQLQGDGFKFFHFMIDLNQ
                     GPCVIKRITGCGAGNEYLSVTPNGDIYPCHQFVGNEEFKMANIFDEEIVLPENLKNMF
                     REAHVYTKEECKQCWNKFYCSGGCHANAINFNNDISKPYELGCEMQRKRTECSIMIQA
                     KLMLEGATN"
     gene            5319..5816
                     /locus_tag="KR231_001640"
     CDS             5319..5816
                     /locus_tag="KR231_001640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma carbonic anhydrase family protein"
                     /protein_id="HBH0004020.1"
                     /translation="MIRDYLEDKPLIDESVFVAKSADVIGNVKIGKDSSIWYNAVVRG
                     DEGPITIGENTNIQDCSIVHGDTETIIGNNVTVGHRSIVHGCKISDNVLIGMGSIILD
                     NAEIGEYTLIGAGTLITSNKKFPPGVLIMGSPGKVVRELTEEDKKYIDESYEWYLEAA
                     QNQKY"
     gene            6114..7778
                     /locus_tag="KR231_001641"
     CDS             6114..7778
                     /locus_tag="KR231_001641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891005.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AarF/ABC1/UbiB kinase family protein"
                     /protein_id="HBH0004021.1"
                     /translation="MRISYRNLKRYREIGYVLIKYGFSFIVERLNIEGIAYKIPLFDP
                     PEEIKNMTTGERMKRVLEELGPTYIKIGQILSTRKDLLDQDIIDEISKLRDDVEKFDS
                     NIAIDIFKEEVGLSIEEIFLEFKEEPIAAASIGQVYEGVLKTGEEVIVKIQRPNIEKI
                     IKSDLEILRTIANTLKDLKKDFNLDLVQMIEEFQTQLMRELDYTFEAINATKFSRIFK
                     NSDEVYIPKVYSEYNTKKILVMEKVNGTKLSDVEKIRRLGYNTKTIVEIGVRSFFTQV
                     LSHGFFHADPHPGNIFVVAKNKIAYIDFGMIGIIDNKTLNQLNEIALAGVEKNVDKII
                     YLLIEMDALNGEADIKGLRQDLLYLIHYYYDISIEKINVTDILNELFRFFRQYKIVMP
                     AQFVTLAKTVITLEGTSRTLNTDFSFGSMGKEFMKHHYKSKFNPKNVVLSSRQNVEEI
                     LLDIKTIPKQLKAILKNIERNNIKMQIEDVKMTRLENCIIELTSQISLSLVLASIIVG
                     SSLIIASPNIENNIWIKFTAIAGFFISFIIGLCLVIRSIRSKYKKD"
     gene            7791..10241
                     /gene="recJ"
                     /locus_tag="KR231_001642"
     CDS             7791..10241
                     /gene="recJ"
                     /locus_tag="KR231_001642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded-DNA-specific exonuclease RecJ"
                     /protein_id="HBH0004022.1"
                     /translation="MKKWILKYKGKIEESEFSKKLNISPEICQILKNRGICTEKDSEI
                     FMNPSLDYLRDPFLMKDMQKAVDRIKLAVEKNEKIWIYGDYDVDGVSSTSILCLYFKS
                     IGYNVDYYIPNRLEEGYGINEDAIKLISSRGCDLIISVDCGITSVSEVNTANDLGIDV
                     IITDHHECQSEIPSAFAVINPKQEDCNYPFDSLCGCGVAFKMIQALTPKEEFKTSMYN
                     YLEIVTLATICDIVPLIDENRIIVKNGLKSMKEGKNIGLRELIKVCGVESDKIGSSHI
                     GFAIGPRINASGRLGYSYLGVELFTTQSQEEAVEIASILEEKNNERQMIEAKMYHEAE
                     EMLKSNSRYNDDKVLVLAKEGWQHGIIGIVASKLTEKYYKPTILLGIENGEATGSARS
                     IKGFNIFEALIKCKDLMTKFGGHEQAAGLSLDSDNVEILANEINKFADYNLTEDDMIE
                     NVNVEFELQENVINLNLVEELHKLEPFGLNNPNPRFIVRNYILKDLKVIGKNQQHLKL
                     SIEKEKSYECIGFNMSHLKSMYKVGDKVDVLFQLDENNYMGNRKVQFLLKDIRLARPK
                     SASNDKLSLKLMSKIIPKDTQSLYNISVSDFELFDGNTDINIFDYFEKDTLIISNSIN
                     GFYRAMSDISLIDLDFNINYNIIEDDSKNTDKLELIFSPNIDKIDLKRYNNIILYDYL
                     YNKGEYSYIYENKREESEIIKYYNKTDLLYLKNVVSNIVPSRDEFITIYKQALIKKEI
                     DLDMVNIRETFNVIPLKFFTILNVFRELNLLDFNLNYEKNSVLIRILPKPQKKLDLNE
                     SLILNNLKNLEKQYNSSY"
     gene            10254..10766
                     /locus_tag="KR231_001643"
     CDS             10254..10766
                     /locus_tag="KR231_001643"
                     /EC_number="2.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenine phosphoribosyltransferase"
                     /protein_id="HBH0004023.1"
                     /translation="MDLKNFIRNIDDFPKPGIDFKDVTTLFKDGDAFKYAVDSIVEEL
                     KDKDVDLVIGPEARGFLMGTPVAYALGVGFVPIRKPGKLPGEVESYEYGLEYGTDTLE
                     IHKDAIKKGQKVAIVDDLLATGGTMEAAAKLVEKLGGEVVSMQFLIELKFLNGREKLS
                     NYDVNSLIKY"
     gene            10840..13047
                     /locus_tag="KR231_001644"
     CDS             10840..13047
                     /locus_tag="KR231_001644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003229747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional (p)ppGpp
                     synthetase/guanosine-3',5'-bis(diphosphate)
                     3'-pyrophosphohydrolase"
                     /protein_id="HBH0004024.1"
                     /translation="MHDKELQEIIEKIKVYAPNANFEMVEKAYNLAKKAHEGQYRKSG
                     EPYFIHPLAVANILIEMELDIETITAGLLHDVVEDTEYTYEDIKKEFGKEVADLVDGV
                     TKLGQIKYRSKEETQSENLRKMFLAMAKDIRVILIKLADRLHNMRTLKYMPPEKAKYK
                     AKETLEIYGGIAHRLGISKIKWELEDRALRFMDPEGYYDLVSRVSMKRSQREDYIQGI
                     VELLKDKFKDLSIPCDVYGRPKHFYSIYRKMQKKHKTFEEIFDLTAVRILVDNVKDCY
                     AVLGIVHTLWRPIPGRFKDYIAMPKPNMYQSLHTTVVGPDGEPLEIQIRTHEMHNIAE
                     NGIAAHWKYKEGISSKESKVEEKLQWLRQMMEWEKDLKDPQEFMDALKEDVFNSQVYV
                     FTPKGDVIELPAESTPIDFAYRVHTNVGNKCVGAKIDGRIVPIDYKLQNGNIVEVLTS
                     SNSNGPSRDWLNIVKTPNAKSRIRQFFKKERREENVDRGNTILEREFKKHDIPQKDPL
                     VEKYMALVAKKFNQPSVEDLIATVGYGGIMSSQVVSKVKDLYLKEVKKAKKEQQIQEE
                     DLNKHNISETEYSKKRKKNASQGIIVKGLDNILVRFAKCCNPLPGDEIVGYITKGRGV
                     AIHRADCPNANNNGDFFQNRLVEVSWSSAGKGKFEAEIQIKAIDRRGIVNEITHIVAM
                     DKLSLNGINARKGKDSIVSINLLVEVNDTEELKILMKKLKAIPGVESIYRMTN"
     gene            13072..13521
                     /locus_tag="KR231_001645"
     CDS             13072..13521
                     /locus_tag="KR231_001645"
                     /EC_number="3.1.1.96"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003517065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-tyrosyl-tRNA(Tyr) deacylase"
                     /protein_id="HBH0004025.1"
                     /translation="MRAVVQRVSSSKVTVDENTIGQINKGLLVLLGVTHDDKSSDVDY
                     MIDKILNLRIFEDENDKMNLSLMDIGGELLVVSQFTLYGDCRKGRRPGFSNAARPELA
                     NNLYEEFVKKAKDKGVTVGTGQFAAHMMVELTNDGPVTILLDSSKSF"
     gene            13536..14150
                     /locus_tag="KR231_001646"
     CDS             13536..14150
                     /locus_tag="KR231_001646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HBH0004026.1"
                     /translation="MIIKKFVDSYFGVNTYVLGDEKTKKCAVIDPGGSLVETLSFVKE
                     NELNIEYIILTHGHGDHIGYVKDIKEKTGAKVVAHVDEKELLNDKNKNLSYTMRCGAQ
                     EFDADIYVNDKDKLELGELKMTFLHTPGHTQGCMCIRVEDEMFTGDTLFAGSIGRTDL
                     YSGDFNQMEKSLKKLCKYEDAVRVYPGHGPTSTLGVEKKTNPYM"
     gene            14241..15797
                     /locus_tag="KR231_001647"
     CDS             14241..15797
                     /locus_tag="KR231_001647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="coproporphyrinogen III oxidase"
                     /protein_id="HBH0004027.1"
                     /translation="MLYVFLKGHDYKYEVAEFIKLFTSEFKFKDSNANNNIESKHLIN
                     RLIYENGVLFSSTEYYENGNLKYESIQNIENMNLEFLDGFDSSKTIEEFLNSLDSESK
                     RNFKKLCKENIKKSMFLVLKQVFNSYVPWGILTGIRPVKIVHNLMDKKLDDNSIRTIL
                     KDNYFIIDEKIDLALEIAKRERLFMYPIDKNKISLYVSIPFCPTRCVYCSFPSNSLKQ
                     FGHLKREYVYKLIEEIKGFAKVIKDTKKEVETLYIGGGTPTTLDEEELDLLINSLFNE
                     LDLSKIKEFTVEAGRPDTITEQKLRVLKKHNVSRISINPQTMNDDTLVKIGREHRVSD
                     LVDCFNMARRMGFDNINMDIILGLIDEDLNMVKNTLEEIKKLSPESLTVHTLAIKRAS
                     NLNINMDRYKEHLTQYEEMVKMIDLSMKYAKDMGLNPYYMYRQKHMLGNLENIGYAKE
                     GYECIYNIQIMEEKQSNYALGAGAISKFVYVDEDRIERVENVKNVEQYIERVDEMIKR
                     KKEEVYKNVD"
     gene            15787..17049
                     /locus_tag="KR231_001648"
     CDS             15787..17049
                     /locus_tag="KR231_001648"
                     /EC_number="6.1.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine--tRNA ligase"
                     /protein_id="HBH0004028.1"
                     /translation="MLTKAPRGTKDITPKEAYKWRYVENKFREICALYGYEEMVTPIF
                     EHTELFKRSVGDTTDIVQKEMYSFKDKGDREITLKPEGTAGVVRAFIENKLYADTQPT
                     KLFYVTPCFRYERPQAGRQRQFHQFGIEALGSDTPSMDAEIIALAVQFFNEVGLNDLV
                     VSINSVGCPVCRKEYNALLKEYLDSKADILCDTCNERREKNPMRVIDCKNPTCKENIK
                     DIPFIADHLCDDCKSHFDKLQEYLKEMNINFVIDKTIVRGLDYYRKTAFEIISNDIGA
                     QSTVCGGGRYDGLVEQLGGPKGISGIGFGLGIERLLLTLEGNGIEIENPQSTDIFIVT
                     IGEEANTRSFKLLKDLRQNHISADKDHIERSVKAQFKYSDKINSKFTIVIGDDELKND
                     TATLKNMKTSEQTTVKLSTLVEELKQKL"
     gene            17123..18910
                     /gene="aspS"
                     /locus_tag="KR231_001649"
     CDS             17123..18910
                     /gene="aspS"
                     /locus_tag="KR231_001649"
                     /EC_number="6.1.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--tRNA ligase"
                     /protein_id="HBH0004029.1"
                     /translation="METLKGLKRTHYCGELREKNINEEVVLMGWVQKKRNLGGLVFVD
                     LRDTSGLCQIVFDTDVDKEAFEKAEKLGAEFVIAVKGKVCERQSKNPNMLTGDIEIFA
                     TELRLLNKSETPPIYIKDDDDVSEALRLKYRYLDLRKPSMQRNLKLRHKVMNITRNYL
                     SNNRFCEIETPFLIAPTPEGARDYLVPSRVNPGKFYALPQSPQLYKQLLMVSGMDRYF
                     QIVKCFRDEDLRADRQPEFTQIDCEMSFVEQEDVMSMIEGLLEAIFKEVLDVELALPL
                     PKMTYAEAMSKYGSDKPDTRFGYELTDISDVVCNCGFKVFADATQPGKSVRGINVKGK
                     ADDFTRKQISSLEEHAKTYRAKGLAWMKVGQEGVTSPIAKFFNEEEMNAILTRMNAEV
                     GDLLLFVADKNSIVFDALGQVRLEVANRLNLLDKNVYNLLWVTEFPVFEEDEETGTFS
                     AMHHPFTSPMDEDLDKLEEGDKSSLRAKAYDIVLNGYEIGGGSVRISNSDVQSRMFKA
                     LGFTEERANEKFGYLLEAFKYGTPPHAGLAFGLDRLVMLLAGTDNIREVIAFPKNQNA
                     VCPMTNAPTLAEDEQLEELSIKVDIKDNE"
     gene            19369..20601
                     /locus_tag="KR231_001650"
     CDS             19369..20601
                     /locus_tag="KR231_001650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytosine permease"
                     /protein_id="HBH0004030.1"
                     /translation="MQEREELVLNPVPKEERVGWLAPLFNMLGSNIAISELMVGGTLI
                     LGMTLSNMIITSIIGNLILVAIIMIQGYIGYKEGLNTYVLAKGAFGEIGGKYLISLLL
                     GITSFGWFGVQAGVAGLSVQKIFPSVNLTLVTVILGLFMVVFALYGFKAMAKFNYLVI
                     PPLMILMVWGVFKAFSTYGVEAIYNYTPQTTMSMVEGLNIVVGLVIVGAIISPDQLRY
                     TRRVKDIWIISFLGLGIISLFQQVAAGVMSMGAPTWDITEVLANLGFGWVAFVILILA
                     SWSTNVSNAYSGGLALKTIFPNVKRNVLTLVAGLIGTIIAATGIIFKFQSFLSFLGIA
                     VPAIAGIMWCEYYFIQGRTYKHREGINWIAVISWLIGFAASYYSSKINFLIPPINGIV
                     VSMVIYYILMKCFGIKDK"
     gene            20615..21421
                     /locus_tag="KR231_001651"
     CDS             20615..21421
                     /locus_tag="KR231_001651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbon-nitrogen hydrolase"
                     /protein_id="HBH0004031.1"
                     /translation="MGRKVKIGIIQQHSVLGDVKKNIEKAVEMIDDLGKQGADIICLP
                     ELFATGYNLESLGGVKTLELIREHNKYIEESMSEAAKRNNVYLISPYGTLEKGSTHVY
                     NSAVIFDRKGKIMGEYCKNHLWSLEAVYFKGGEKVEVYDADFGRFGVMICYDAGFPEV
                     SRELTLKGSEIIFIPSAWRIQDEDMWDLNVSQRALENTVYTVGVNLVSNDSNLILFGK
                     SKICNPRGTVITQLDTYREKYVLSEIDLDEIKKYREDIPYLKDRKSSYNI"
     gene            complement(21533..22402)
                     /locus_tag="KR231_001652"
     CDS             complement(21533..22402)
                     /locus_tag="KR231_001652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HBH0004032.1"
                     /translation="MDLLHLKYFQTVARMEHITKASHKLNIAQPALSKTISSLEKELG
                     VQLFDRKGRYIVLNEYGRLFLKRVDSILDLVESSKKELQDTSLENSGEVKILSPAAAN
                     VLPSLLSNFRKLYPNITFNVSHTLPSSYKKSDFDLYISSSFTKLNSENSITLTCEEIL
                     LGVSINHPLSLKDEVYLSEVSDENFIVITKGENYREVIDILCESANFKPKIAFESDSP
                     YTIYALIKSLQGVGFICGKSWGLSQDPEIKLLHIKDIEFKRYLNLSWFSENYESKAVL
                     LFKNFLINYFKNI"
     gene            22774..24201
                     /locus_tag="KR231_001653"
     CDS             22774..24201
                     /locus_tag="KR231_001653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp14"
                     /protein_id="HBH0004033.1"
                     /translation="MKLTKSISSMLCLSLVLSLSPVAYANEISRTTVENTLVGQDRYQ
                     TAVEVSKKGWSSANEAVVVNSESIVDALAVTPFAKLKNAPILLTEKNNLNSQTEKELK
                     RLGVKKVYIIGLSSSVSNDVQKQLESNNLTTDRVGGSDRYQTALSIAKKIEGLKDISE
                     IAVVNGYTGLADAVSIGSVAATNGMVILPVSDASGISSFKDFIESKNINKSYIIGSTN
                     AVSDKIKQSLPNSERIGGADRNETNGKVIEKFYTSNKLNNVFVAKDGMKNQNQLIDAL
                     AVGVLASKENSPVLIVGEQLSATQKSVFSNKNATSITQVGSGGNENAFKELKDLQANS
                     NNKRVMYVTNTDKVNIRNDATIEASVIGYLNNGDEVEVLDVLKTGWVKIKYNEGIGYV
                     SGSYLTNNKPDNSNENIKIKYVKEKDGLNVRKGPSTEDEKIGHLSYGSKVETIEMFAT
                     GWVKIKYNGGYGYVSNDYLSDTPVI"
     gene            complement(24278..24547)
                     /locus_tag="KR231_001654"
     CDS             complement(24278..24547)
                     /locus_tag="KR231_001654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0004034.1"
                     /translation="MKFEYYYLIQDIAGILLAFIGLRMSIIGFRILSMRGLSINTLLI
                     VIKYCLFTIAGLNLLISKFGIRHWIWSVCMLIISIIINPRIKVSK"
     gene            complement(24550..25992)
                     /gene="nhaC"
                     /locus_tag="KR231_001655"
     CDS             complement(24550..25992)
                     /gene="nhaC"
                     /locus_tag="KR231_001655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Na+/H+ antiporter NhaC"
                     /protein_id="HBH0004035.1"
                     /translation="MKMNTERKIPSFRYSLLVMLAIIALTSVGIVVFNASITTMFLLS
                     WLIVVPAAMKLGYTNDEIEAFGFEVGKDAFQSNLIILSVGVLIAAWIAAGTIPTVVYS
                     GLTIITPKYFLLTTLIVCSLTSVATGTSWGTLGTSGIAMMSIGTSMGIPLGLTAGAVI
                     SGAFFGDKMSPLSDSTNLAAAVCKTDVITHMKHMFYTTGPAYVICIVLYTVIGFKYSN
                     NTIDYVQINQIKDVLNSNFHIGLVAMIPIIFLLLLLLLQKPPIISILSSAIMGLIIAV
                     FQEGEKIGDVLNYMLSGFTIDTGFVYADKLLNRGGIMSMAETVLLVFVVFVIAGILQK
                     TGFLEVLLQPLITKIGKSRTKLVGSTFIVSYFANAFSSSMMFTSVFVGTLMSPIYKEF
                     KLKPQNLSRIIEDTATLGGPLIPWNSNAVFCAQTLGVSPLEFIPYCFLSWITPIISFI
                     YGVTGFTMLTYTDDEIEELEIFDTAQRRVD"
     gene            complement(26017..27183)
                     /locus_tag="KR231_001656"
     CDS             complement(26017..27183)
                     /locus_tag="KR231_001656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HBH0004036.1"
                     /translation="MNYNFNEIVDRSNNFSSKWSEMEKKYGTNDLLPMWVADMDFKAA
                     PCIIDSLKNRLEQEIYGYTTRPDSYNESIVNWLDRRHNWKIKSEWLIYSPGVIPAISL
                     LINELTKANDKIMIQEPVYSPFNSVVKNNNRELIISPLQKLENGNYIMDYEDIENKIK
                     DVKLFILCNPHNPVGRVWTKDELKKLGDICLKHNVKIISDEIHSDIILKKHKHIPMAS
                     ISKEFEKNTITCMAPTKTFNIAGLQSSYVILPDEKYYKLLDDAFTRIDIKRNNCFSLV
                     ATEASYNNGESWLESFLEYLESNIDFAIKYINENMPKLKVRKPEGTYLLWVDFSALGL
                     SDEELESILVQKGKVALNQGNSFGIGGSGYQRINLACPRSMLEEALIRIKNAIN"
     gene            complement(27408..29528)
                     /locus_tag="KR231_001657"
     CDS             complement(27408..29528)
                     /locus_tag="KR231_001657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HBH0004037.1"
                     /translation="MKQMELAIVSLKKDAGEIYENQIRQFLGDNLKINLYSFEEGNLK
                     FFKEKLILLSAYLKYDEIVKLSHYDAQIIVPKLTFEKNSIDMISKLEKDKIIYVYNLS
                     KDMAIETISLIHRLGIDNINILPCYPEIEFTPTDAVILTPGEKILPKFKNCEVIDLKY
                     RIIDLSCIVEIATKTKLKHLIKDDLIKKYVEKIIPTSYSTGELLLDANKFERQFDLLL
                     SIIDDGIICTNNDGIIQFYNHMARKILSINANEMIDSFVGDCIKDINFQSILTNKTPF
                     FEKLIKINHIDINLEIKHIQLNVFDGFILKMTKFSQLEKKQAKLRAQLVNSGNISKYT
                     FDDILGSSIQTINTKKIANKMAQSNSSILIIGESGTGKELFAQSIHSASRRKDDPFVA
                     VNCSTFQENLLQSELFGYDEGAFTGAKKGGKIGLFELANNGTIFLDEIGEMDLNSQSK
                     LLRVIQEKQVRRIGSNNVIDIDVRIIAATNRNLKELVSKNMFRRDLYFRLNVLPLKIH
                     PLRERPADIFEIFGSLKYDIPCNFILSEEVKEIFKMYRWEGNVRELRNLGEYFCYLEK
                     DIIEICDLPEYILDTIDSNYSRTVCNKVSNNIKKYQFNIGKDKNIMKYDYNFKRSLDE
                     YIFILDNLKKAYDLKERIGRKSLCKIALEENRFLTEQQIRNMLLELQDFGLVDILVGR
                     GGSIITSKGVEFLKNINRSNKLNS"
     gene            29761..30162
                     /locus_tag="KR231_001658"
     CDS             29761..30162
                     /locus_tag="KR231_001658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0004038.1"
                     /translation="MKKCLYCNRDIKSPNNKLAIKYDDNMNIYPCRAECKEKIEEYIA
                     KKPTYKFINILEVLLGVGGIFCFLSKWTIAAQVVLGIDALVIFLFPLAGFKMNGKLSM
                     EQTKNQSRSIAISILAFIVIITVLYFKQIGK"
     gene            30205..30498
                     /locus_tag="KR231_001659"
     CDS             30205..30498
                     /locus_tag="KR231_001659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sensitive transcriptional regulator"
                     /protein_id="HBH0004039.1"
                     /translation="MEERKLAPNNEREALIKRLKRIEGQVKGIQKMVEQERYCVDILV
                     QISAIRSAINRVGTIILENHIKGCVAESIKHDDADKTEEMIKELMDTINKFTK"
     gene            30513..30953
                     /locus_tag="KR231_001660"
     CDS             30513..30953
                     /locus_tag="KR231_001660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SoxR reducing system RseC family protein"
                     /protein_id="HBH0004040.1"
                     /translation="MNQQGFIMEIVDDRTAKLKMQRHSACAACGKCATTNSAESKEIL
                     VEVDNTIGAKVGDHVEVSMDNMNVLKAAVMAYIIPLIALLVGTIGTYYILGAIGMTTG
                     VEAISGLVGICLTIICYLYLKKNDKKFRDSREFIPVITRILIDL"
     gene            complement(31045..31518)
                     /locus_tag="KR231_001661"
     CDS             complement(31045..31518)
                     /locus_tag="KR231_001661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HBH0004041.1"
                     /translation="MTDMSMILHFLFSGVATAGFAVFFNAPLYLLLPAGVTGGIGWIV
                     YVYLFNFTTNAVFAGFIAAALVSACSETLARKLKQPAIVFVIPGILPLIPGIGLYNTM
                     LSLIQKNYSLAMSKGTDALFLSAAIALGVLVVTSFVRTLNLLKIRKNFIPYRKSK"
     gene            complement(31518..32306)
                     /locus_tag="KR231_001662"
     CDS             complement(31518..32306)
                     /locus_tag="KR231_001662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HBH0004042.1"
                     /translation="MNQNEELEYKKNILKLALFVGELMIKNGAETSRVEDSVLRICRS
                     RGFYHVNIFTTPTVIIISDEKFDGFSFMKTIQSRGINLNKISLLNSFSREFVSDKEYD
                     IDNAIARLYEIQDVKPYPLWLFYSCTGIASACFACLLGGNYVLNFILTFIIAIFAAIT
                     YDKTMKISAISAFSCLVSSFLIALSGVLLVEIGILDDPKMLIVGAIMPLLPGVAFIKA
                     IRDLISGNLISGISRAFDAAMIIIAIASGVGFVLDTWYRIGGPF"
     gene            32634..33878
                     /locus_tag="KR231_001663"
     CDS             32634..33878
                     /locus_tag="KR231_001663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydroxymethyltransferase"
                     /protein_id="HBH0004043.1"
                     /translation="MFENLKKADPEIYESMKRELKRQQRNIELIASENIVSVPVMETM
                     GSHLTNKYAEGYSGKRYYGGCEYIDEVETLAIDRIKKIFGAEHANVQPHSGANANIGV
                     YFAMLKPGDVVMGMNLSQGGHLTHGAPVNISGQYYKFYEYGIDKDSGLIDFDEVRKIA
                     HEVKPKMIVAGASAYPREIDFKKFREIADEVGALLMVDMAHIAGLVAAGLHQNPCEVA
                     DFVTTTTHKTLRGPRGGVILCKEKYAKDIDKAIFPGIQGGPLEHIIASKAVCFKEALS
                     DEFKEYQVQVAKNAKALAEELIKRDFKLISGGTDNHLILLDLTNKNITGKAAEKRLDD
                     AYITANKNTIPFDPNGALVTSGIRLGTPAVTTRGMKEEDMAIIAEAIDLCLTYDEESK
                     ARTLVVGLTEKYPLYEEYNIMD"
     gene            34201..35298
                     /locus_tag="KR231_001664"
     CDS             34201..35298
                     /locus_tag="KR231_001664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-diphospho-muramoylpentapeptide
                     beta-N-acetylglucosaminyltransferase"
                     /protein_id="HBH0004044.1"
                     /translation="MKVLILTGKFGMGHYSASNSLSEDIKAKFDNSEIIIKDIFEYIM
                     PNYSDKMYKTFSILVNRGSSLYNLFYKCAENGKKDIKFTFSDYFLNKLDTLLHEVQPT
                     VVISTFPFCSQLVSRYKEKYNSNLPLITCITDISSHSEWISKNTDCYLVASKSTKEEL
                     VFKGIDESKIKVNGIPVKKEFKRIEHVNHSTKKNILIMGGGLGLLPKSEQFYKELNSL
                     EGVKTTVITGNNKKMYYKLYGRYENIEVVGYTNEVYKYMKDSDLIISKPGGITLFETI
                     YSELPILAFNPFLQQEIDNASFILNNEIGRILGKNKKYYVDEIKDLIYDDATLKEMSS
                     NMKELKKQFDNNTLENILFSLDEQGACRECM"
     gene            35289..35987
                     /locus_tag="KR231_001665"
     CDS             35289..35987
                     /locus_tag="KR231_001665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HBH0004045.1"
                     /translation="MYVVGLIIVVALIFLVHSIIPTYYNKLLNKEVLKNMAGENEIAL
                     TFDDGPDKRYTEKLLDVLKENDIQAMFFVVAKNAEKEPEIIKRMLRENHIVGLHSLEH
                     RNAWLYSYSYVKKDFIESTNIMKNLGVDVNYYRPPWGHTNIFSNSFVKKYNLKMTLWD
                     VMAEDWEKDSTVDIIINKLMSRTKENSIICLHDAGENSGGAVGAPERTIEALKIAIPK
                     LKASGLKFVTPERM"
     gene            35990..37054
                     /locus_tag="KR231_001666"
     CDS             35990..37054
                     /locus_tag="KR231_001666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flippase-like domain-containing protein"
                     /protein_id="HBH0004046.1"
                     /translation="MISKTEKKNKCLGSVAFLVLLMGITGYFVFRGQSVESLIKSLKG
                     ASPMFILIGFAMMFIYVACEGINIYLGMKALNQKTTLLKCMGYAFIGFYFSSITPSAS
                     GGQPAQVYYMKKDDINISYSSLILLVIVVIHQVVILAYSGIMFIMEREFILNNVSGMN
                     ILLIYGVITNVALVIGVIAIIFSKKLVNNFIISITNLLGKLRIIKDVESSRKVIISQI
                     EEYVKGAQYIKQNPKLVVQILVITIVQITSMFLVPFFVYKAFHLSTYTVFEILAIQSL
                     LNIAVSSLPLPGAVGASENSFMTLFKIFFPGHLLVPAMLLSRGISFYAFVAISGLICI
                     VVHVKSSEKVKAVKKVAYVR"
     gene            37237..37941
                     /locus_tag="KR231_001667"
     CDS             37237..37941
                     /locus_tag="KR231_001667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBH0004047.1"
                     /translation="MNKEIPKKILVADDNPEIREIVEILLTGEGYEVIMATNGEEAVN
                     LVDSTIDLIILDVVMPVKTGFVACNEIREKTTAPILFLTAKTQDSDKVIGFSAGGDDY
                     LSKPFSYSELISRVKSLLRRYYIYQGKEKEREPNILKTKELCVNLDTQDVTLNGEPVF
                     LTTIEYSILILMLKNRKKVFSSENLYETIWDEQYFYTANNTIMVHIRNLRKKLEKDQK
                     NPQYIKTAWGKGYYID"
     gene            37934..39256
                     /locus_tag="KR231_001668"
     CDS             37934..39256
                     /locus_tag="KR231_001668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBH0004048.1"
                     /translation="MINKIKPSKLGVILLIYVVISAAVAFILNIPFYSAVESIVKDVS
                     EGKVYFKREVNQLMDNFQTYVNNNGIRADDGDDIAKWNSDNWFVSMKIYKGNKVFYDT
                     LYYPNEVPDKSEENEFYSSPMARNYEIQFSDIKANIVVVALFRFRFQNFIEAISITFM
                     ALTFIITFLLLFSRKIKYLRKIEMGIKIVESGSLKYRIPVKGNDELSSLASSINEMSH
                     TLENQLIKEREMKNKNKDIVTSISHDVRTPLTSVICYLDLIKDHKYNSPEQLEQYIKN
                     VRSKAYQIKDLTDDLFTHFVNSGEEVSKGYEKINANEFIFQLLLDSSYTLEEKGFHIT
                     IENELYNQYHIYVDVTQFRRIFDNLCSNIIKYARKDKPIVFLIKVEDSKLLIIQKNRV
                     SNFSKNVESFGIGIKNCEKIVAYHNGSINVNSDDKEFAIEISIPAKES"
     gene            39443..40816
                     /locus_tag="KR231_001669"
     CDS             39443..40816
                     /locus_tag="KR231_001669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0004049.1"
                     /translation="MVLTGAHYIYILFMVIILITMIMKKDTIVPCILGVFFMGLFFEK
                     NIFGAITAVFNSFIISLNELGPIILIIAIMVALSKALEANNAIQYMVRPFSRVIKNSN
                     TAFFVTGFVMLVLSWFFWPTPAVALVGAVFLPVAMRAGLPAIGVAVALNLFGHGLALS
                     TDFVIQGAPSITAGAAGVAVSYVINDGMILFWVMGIVTISMAFYTLKRDINKGMFREE
                     LKGFESEEVEAFNGKSKIATILVALGFLADIIAMYVFDLKGGDASALLGGTAVFLIII
                     INVINFGKDSLENVCENIIDGFVFGIKIFGAIIPIAAFFYMGEVAPLTGVFGKVLAPG
                     SQGLLSDIGIALSQTIPLNKFAVSGIETVVGAITGLDGSGFSGISLVGSLASVFGTAI
                     NASVGALAALGQISGIWVGGGCLVPWGLISAAAICGVSPIELAKRNFVPVITGLVVTT
                     IVAMFII"
     gene            complement(41188..42126)
                     /gene="pdaA"
                     /locus_tag="KR231_001670"
     CDS             complement(41188..42126)
                     /gene="pdaA"
                     /locus_tag="KR231_001670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="delta-lactam-biosynthetic de-N-acetylase"
                     /protein_id="HBH0004050.1"
                     /translation="MFRKVLHYLTLLSISIFFIVGCSNSQNNQNENQNKETQLQEDKE
                     KIDSGKDTSNVIVSDGTDKPSKATTNNDNNKLDVSSLDNTTLDWFYIPNNKHKTPEVN
                     TDIEFKFSDYDALYNGPTKDGQKTLYLTFDEGYENGYTTKILDTLKQNQVKAVFFVTA
                     PYIKENKDLVKRMVSEGHIVGNHSKTHPSMPTKTSNLKNFNDELYDVEKLYKDVTGKD
                     MVKFFRPPMGKYSEKSLAMTKNLGYKTVFWSFAYRDWDTDKQPSHEEATQKIMDNLHD
                     GSILLLHAVSKTSTEILNDFISNARKLGYEFELLEY"
BASE COUNT        16323 a         4828 c         7151 g        14097 t
ORIGIN      
        1 tactattatt aatttaatca ataacataat ttaaaattat aatactagtt aagatttcct
       61 gctttattag taaataattc tttaatagca ttgtttctgg aaactaaatc gttatcagag
      121 ttgtttgttt ttttcataat cactgaataa cgttttttat ttataaaaaa tattaaaatc
      181 ttatcatcat caaaattgta ttctttatat ctgtcgatag actcataacc tagatttaga
      241 atgtttttgt cttttatact atctacatct aaaatatatg atgggtcagc ctttagtaat
      301 atattaatta aacatttttc ttcaccagca cagaataact ccatcttact tgatatagat
      361 ttagattgct ctgaagttat ttttgcagga ataaggttgt cattatcatc tcttagaaga
      421 taaccatgtg tgtcttgttg atatactaaa ttaacctttt tcttaggaac actaatcatt
      481 ttatctaaat gtacataatg atgattttca acaaaacctt catttaatat ttcaacaaag
      541 ttattaattt tacctaggca aaaagattct atagattctt tacagaattt atttgtaaat
      601 ggtattatgt ttacgttttc ctcgtctgta ttccatgcta tagcataatc caacgaatat
      661 acttcttcct ctatatctgc aaaattatat tgtactatgt ttcctttcaa aattactcga
      721 cctccatctt ataatatatt taatatactt tataaaactt atattatatt taaataatat
      781 cataaattga ataaatatga tatagtaaat aagaaaaaat ttgaaaaaaa tcactataaa
      841 tgagtaataa atataaatag tgtatactaa tgggatggaa aatgtccact attaacttta
      901 ttaccccaca tatataagat aaaattatta atataaaata taatctatcg acaatgaata
      961 gacttttaaa taaacttaat ataaaattaa ttaaataagt gcttaaaaac gatttacttt
     1021 aatgatagaa tcatattaaa ggaggataat tttatggata taaagaataa aattaaatct
     1081 atatttttac cagaaaaaaa tgactattta gatgatgaag aatttgagta tgatatagaa
     1141 aataatgaag aagatttaaa ggaagataac aaagtacatt taaatgattt aagcagagta
     1201 aaatatgatt acagagagtt aaaagacata gaaaaccaaa cagaagagat gtgtctgcta
     1261 gcagtaaagc aggatggtac tataattgag tttgtaaagg acaagactta taaagtatgt
     1321 atggaagcag taaaacagac atataaatct cttaagtata taacaaatca aaatgaggat
     1381 atttgtatag aagcagtaaa acagaactac agagctttgt actacataaa taataagaca
     1441 gaaaatgtac taattgaggc tataaaaaat gcatcaactt atgatgtcat ggaagtattt
     1501 aaatttgtgg aagagcaaac agaagatgta tgtctagcat ttatagaaag ggcatctaaa
     1561 aatgatgttg cagagatatt aaaaggaata aaagagcaaa ctccagccat atgtttagaa
     1621 gctgtaaaaa aagatggaaa atctttagct tatgtaaagg aacaaagtaa tagtatatgt
     1681 ttagaagctg taaaagaaaa ctacagtgca ctatcttgtg taaaagagca aactgaagaa
     1741 atatgtatag aagcagtaaa acagaatgac tttgcattgt attatgtaaa tgaacagaca
     1801 gaaaaaatat gtatggaagc agtaaaaaga agttatatgg ctctacagta tgtaaataag
     1861 caaacagaag agatttgttt ggaagcagta agaattgatg gaagagcatt acagtacgta
     1921 aaagagcaaa cagaagaaat ttgcttggag tcagttagac aaaatggaaa agtactgcaa
     1981 tatgtaaaaa aacagactga aaatatatgt atagaagcag taagaggttc atttgaagaa
     2041 cttgaaataa aagaaatatt aagttatgta aagataccaa cagaaagaat atttgtagaa
     2101 gcagtaaagc aaaatggaaa aattcttaaa tatgtagaaa atcagacaga attaatatgt
     2161 ttagaggcag taagagaaaa ctataatgct ttagcttatg taaaggaaca aacagaaaag
     2221 atttgtttag aagcagttaa tcaaagttat gaagcgctta aatatgtgaa agaacaaaca
     2281 gaagaagttt gtctaaaagc agtaaaacaa gattatagaa tgttgaaata tgtaaataat
     2341 caaacagaaa aaatatgttt agaagcagta aagcaaaatt atagagcttt agaatttgtt
     2401 gataatcaaa cagaaaaagt ttgtcttgaa gcagtaaaac agaatagaaa agcactacag
     2461 tatgtaaaac aaaaacaaag ttaaaaggct aaaatatata gaaaacatat gcaaataaat
     2521 aaaatttgat attttgtaat aaataaaatg ggtatctcaa aaggaacttt ttagtttgtg
     2581 aggtactctt tttatatgaa atgaaatata tttttagcct tttaacaatg gggaaaaggt
     2641 ttatttctat tttgacatag gctttttatg catataaagc ttgataaaat tgttttatta
     2701 taattgtttt gttatataaa taataagaag aaaattatat aggtcttttt ttgaccagtt
     2761 ttacattttt aacaactagt tttgtaaagt atattgaatt ttctcaaaaa agaatgtact
     2821 ctatatatgt aaaatttttt tggaggtaaa aatgtttaaa agatatgctg aaaaaatgac
     2881 atctgtttta atttgtaata atatgataga taataatgaa tctaaagtct attcttatgg
     2941 atttgaaata ttaatagctt tcatagttaa tataaccacc atgctgttta taggtttttt
     3001 atttggtaaa tttacatatg tattattttt tttaatgtgt tattgtccaa taagacaatt
     3061 ttcaggaggg tatcatgcag acaattattt tagatgctta ttaaccttta tttttataat
     3121 tttatctaca atcttaatta tagaaaatat aaatatagac ttatttaaaa atattattat
     3181 gattattgca agtgttagtt gggttggaat ttgtgttctg tgcccaatag aacataggag
     3241 taaccctata agtgataggg aaaaattggt ttataagaaa actgctatat ttatatctac
     3301 agtagtgtta ttgataacaa ttttaagtct ttctttgagt atatttgtag attatttcac
     3361 atatagcgca tttgccatgt tttggatttt tgtgatgtta gtattaggta agttaaaagc
     3421 taaagtataa gtaaaatatg tatgagggag agttaagtta tgaaaaagtt tattgtaaga
     3481 tttatgaagt ttgctagctc attggcactt agcactgcta ttttgtcagc taatagtacc
     3541 tgtccttgga ttattcatca gcctaaagta cccaaagaaa tcagcaatct aaagaagaca
     3601 aattaaatac aagcacttat ttatacaaaa ttatcaggaa aaaagaaatt attatatttt
     3661 aataagatta aaacaatata aaatcagata caaaatttat tttatttatt ttataggagc
     3721 ctaataccta tttggtaata tattagtgcg ccaatttagg gggatatagt gtatttaatg
     3781 aaatgactta cggagagtaa gtcatttttg tattgtatgt attttatgta aacttatgat
     3841 ataatgaagg gtaaagttta attaaaataa taaaaaactt tagtatagat agtaatttag
     3901 gaggtagggt atgagtatga tacataaatt ttctatgaat ggatataata tcgttttaga
     3961 tgtgaatggt ggagctgttc atgtgttaga tgatgttgca tacgatttgt tagattttta
     4021 taaagaaaaa agtaaagaag aaatattaga gatattaaaa tcaaaatatc aagaagaaaa
     4081 aataaatgaa gcatatgaag aaatattaaa tttggaaaaa gagggtcttt tatatacaga
     4141 agatacatat caatatcatc caagctttgt acatagagag cctgtagtaa aagctttatg
     4201 tttaaatgta gctcatgatt gtaacttaaa atgtaaatac tgttttgcag ctcaaggtga
     4261 ttttggagga gaaaaagaac ttatgagttt tgaagttggt aaggcagcaa ttgactattt
     4321 gattgctaat tcaggaagta gaaagaacct agagatagat ttctttggtg gagagccttt
     4381 gatgaacttt gaggttgtaa aacaactggt tgactatgga agaagtgtag aaaaagatta
     4441 taataaaaat ataagattta caataactac aaatggtgta ctgctaaatg atgagattat
     4501 agattatata aatgaaaata tgcataatgt agttttaagt ttagatggaa gaaaagaagt
     4561 taatgataat atgagaccaa ctttaaatga taaaggaagt tatgatatta cattaccacg
     4621 atttaagaaa cttgtggaaa aaagagcaaa agataagtat tattatataa gaggtacttt
     4681 tacaagagat aatttagatt tttcaaaaga tgttatgcat tttgcagatt taggatttaa
     4741 attaacctct gtagagccag ttgttggaga tgagagtaat ccatatgcac ttagagaaga
     4801 agatttacct aagatatttg aagagtacga aaaatttgct gtagagtatg cagatagaca
     4861 attacaagga gatggattta aatttttcca ttttatgata gacctaaatc aaggtccatg
     4921 tgtaataaag agaataactg gatgtggagc tggaaatgag tatctttctg taactccaaa
     4981 tggagatata tatccatgtc atcaatttgt tggaaatgaa gaatttaaaa tggcaaatat
     5041 atttgatgaa gaaatagtac ttccagaaaa tttaaaaaat atgtttagag aagctcatgt
     5101 atatactaaa gaagagtgta aacaatgttg gaataagttt tactgttcag gtggatgtca
     5161 tgcaaatgcg ataaacttta ataatgacat atcaaaacca tatgaattag gatgtgaaat
     5221 gcaaagaaaa cgtacagagt gctctataat gatacaagct aagttaatgt tagaaggagc
     5281 aaccaactaa atttatattt taaaggagtt gtttatatat gattagagat tatttagaag
     5341 ataaaccttt aattgacgaa agtgtatttg tggcaaaatc agcagatgta attggaaatg
     5401 ttaaaatagg caaagattca agtatatggt acaatgcagt agttaggggt gatgaaggac
     5461 caataactat tggagaaaac actaatatac aagattgttc tatagtgcat ggagatacag
     5521 aaactataat tggtaacaat gtaacagttg ggcataggtc tatagttcat ggttgtaaaa
     5581 ttagtgataa tgtgttaatt ggtatgggtt caataatatt ggataatgct gaaataggag
     5641 aatatactct gataggagca ggtacactaa ttacatctaa taagaagttt ccaccaggtg
     5701 ttttgataat gggttctcct ggtaaggttg ttagagagct tacagaagaa gataaaaaat
     5761 atattgatga atcttatgaa tggtatttag aggcagcaca aaatcaaaaa tattagttta
     5821 aagagtggtt gtttcaaaac atatttaaat ctgttttgag gcaaccacta atttatttta
     5881 ttagattttg ttgatatttt agttttcaaa aagtatttga ttaaaccaga tataaaatgt
     5941 caaaaataaa aattaactga gttaaataat tttaataaaa ttggtagtat atgtgataaa
     6001 attaaatatt aaagaggata taggatatta gaatatcaat tggtgaaata atgtcatata
     6061 cgataaatta aggtgtaagt ttttgggtat acctatctta ggagtgaaaa gatttgagaa
     6121 taagttatag aaatttaaag cgatatagag aaattggata tgttttaata aagtatggtt
     6181 ttagttttat tgtagaaaga ctaaatatag aaggaattgc ctataaaata ccactatttg
     6241 acccaccaga agaaataaaa aatatgacaa ctggtgagag aatgaaaaga gttttagaag
     6301 aactaggacc tacatatata aaaataggac agatattgag tacaagaaaa gacttgttag
     6361 accaggatat aattgatgaa atatcaaaac tcagagatga tgtagagaaa tttgattcaa
     6421 atatagctat tgatatattt aaagaagaag tgggtttaag tatagaagaa atattcttag
     6481 aatttaaaga agaaccaata gcagcagctt caattggtca agtttatgaa ggtgtactta
     6541 aaacgggaga agaagtaatc gtaaaaattc aaagaccaaa tatagagaaa ataataaaat
     6601 ctgatttaga gattcttaga actattgcaa atactttaaa agatttaaaa aaggatttta
     6661 atttagattt agtacagatg attgaagaat ttcaaactca attaatgagg gaacttgatt
     6721 atacatttga agctataaat gcaactaaat tctctaggat atttaaaaat agtgatgaag
     6781 tatatatacc taaagtatat tcagaatata atactaagaa aattttagta atggagaaag
     6841 ttaatggtac aaagttaagt gatgtagaaa aaataaggag actaggttat aacacaaaaa
     6901 ctattgttga aataggagtt aggtcatttt ttacacaggt attatctcat ggattttttc
     6961 atgcagaccc acatccaggt aatatattcg tagttgctaa aaataagata gcatatatag
     7021 attttggaat gattggaatt attgataata aaactttaaa ccaattaaat gaaattgcat
     7081 tagcaggtgt agaaaagaat gttgacaaga taatatatct attgatagaa atggatgcat
     7141 taaatggaga ggctgatatt aagggactta gacaggattt actttatcta atacattatt
     7201 actatgatat ttctatagaa aaaataaatg taacagatat attaaatgaa ctatttaggt
     7261 tttttagaca gtataaaata gtcatgcctg cacaatttgt aactcttgca aagacagtta
     7321 taacattaga aggaacaagt agaactttaa acacagattt ttcttttggt tctatgggaa
     7381 aagagtttat gaaacatcat tataagagta aatttaaccc taaaaatgtt gttttaagtt
     7441 caagacaaaa tgtagaagaa atattactgg acataaaaac tattccaaag caattaaaag
     7501 caattttaaa aaatatagaa agaaataata taaaaatgca aattgaagat gttaaaatga
     7561 cgaggttaga aaattgtata atagagctaa catctcaaat atctttgagt ttagtgttgg
     7621 catctattat agtaggttct tctcttataa ttgcatctcc aaatatagaa aataatatat
     7681 ggataaaatt tactgcaata gcgggtttct ttatatcctt tataataggc ctttgcttag
     7741 ttataagaag tattaggtca aaatacaaaa aagattaggg ggaattaaat ttgaaaaaat
     7801 ggatattgaa gtataaaggt aagatagagg aaagtgaatt tagcaaaaaa cttaatattt
     7861 ccccggaaat ctgccaaatt ttaaaaaata gagggatatg tactgaaaaa gattcagaaa
     7921 tatttatgaa tccatcttta gattatttaa gagacccttt tttaatgaaa gatatgcaaa
     7981 aagctgttga tagaataaag ttagcagttg agaagaacga aaaaatttgg atttacggag
     8041 attatgatgt tgatggtgta tcatctacat ctatcttgtg cttatatttt aagagtatag
     8101 gttacaatgt tgattactat attcctaata gattagaaga agggtatggt ataaatgaag
     8161 atgctattaa gcttataagc tctaggggat gtgacttgat tataagtgtt gactgtggaa
     8221 ttacatcagt gtctgaggtc aatacagcga atgatttggg catagatgtt ataattacag
     8281 accatcatga atgtcaaagt gaaattccat cagcctttgc agtaataaat ccaaaacaag
     8341 aagattgtaa ttatccattt gattcactat gtggatgtgg tgtagcattt aaaatgattc
     8401 aagccttgac tccaaaagaa gaatttaaaa ctagtatgta taattatttg gaaatagtaa
     8461 cactagcaac tatttgtgat attgttccac ttatagatga aaatagaata attgtaaaaa
     8521 atggtttaaa atcaatgaaa gaaggcaaaa atattggatt aagggagctt ataaaagttt
     8581 gtggtgtaga aagtgataag ataggttctt ctcatatagg ttttgcaata ggtcctagga
     8641 taaatgcttc aggtcgattg ggatattctt acttaggagt agagctattt actactcaat
     8701 cacaagaaga ggcagtagaa atagctagta tattggaaga aaaaaataat gaaagacaga
     8761 tgatagaagc taagatgtat catgaagctg aagaaatgct aaagtctaat agcagataca
     8821 atgatgacaa ggtgttggtt ttagctaaag agggttggca acatggaata ataggaattg
     8881 tagcatcaaa gttaactgaa aaatactaca aaccaacaat tcttctaggt atagaaaatg
     8941 gggaggctac tggttcagcg aggtcaataa aaggatttaa tatatttgaa gctctcataa
     9001 agtgcaaaga cttgatgact aagtttggtg gtcatgaaca agcagcaggg ttatccttgg
     9061 attcagacaa tgtagaaatt ttagcaaatg aaataaataa atttgcagat tataatttaa
     9121 ctgaagatga tatgatagag aatgtaaatg ttgagtttga attacaagaa aatgtaataa
     9181 atttaaatct tgtagaagaa ttacataagt tagaaccctt tggattaaat aatcctaatc
     9241 ctagatttat agttagaaat tatattttaa aagatttgaa agttataggt aagaatcaac
     9301 aacatctgaa attaagcata gaaaaagaga aaagctatga atgtatagga tttaatatga
     9361 gtcatttaaa atcaatgtat aaagtaggag acaaggtaga tgtactattc caattagatg
     9421 aaaataacta tatgggaaat aggaaagtac aatttttact taaagatata cgattggctc
     9481 gacctaaaag tgcaagtaat gacaaacttt cattgaaatt aatgtcaaaa ataataccaa
     9541 aagatactca aagcctgtat aatatatctg tgtctgattt tgaattattt gatggaaata
     9601 cagatataaa tatatttgat tattttgaaa aagatacact aataatatct aattctataa
     9661 atggatttta tagagcaatg tcagatatat cacttataga tttggatttt aacataaatt
     9721 acaatattat tgaagatgat agcaaaaata ctgataaatt agagcttata ttttctccta
     9781 atattgataa aatagactta aaaagatata ataatattat tctttatgat tatttataca
     9841 ataaaggcga atattcgtat atatatgaga ataaaagaga agaaagtgaa attataaaat
     9901 attataataa aacagaccta ttatatttaa agaatgtagt tagtaatata gttccatcaa
     9961 gagatgaatt tataacaatt tataaacaag cactcataaa aaaagaaatt gatttggata
    10021 tggtaaatat aagggaaact tttaatgtaa ttccattaaa gttttttacg atattaaatg
    10081 tatttagaga attaaattta cttgacttta atttaaatta tgaaaaaaat tctgtactca
    10141 taagaatatt gccaaaacca cagaaaaaat tagacttaaa tgagagttta atactcaata
    10201 atctaaaaaa tttagaaaaa caatacaata gcagttatta ggaggcgttt cccatggatt
    10261 taaaaaactt tataaggaat attgatgatt tcccaaagcc aggcatagat tttaaagatg
    10321 tgacaactct atttaaagat ggagatgcat ttaaatatgc agtggattct atagttgaag
    10381 aattgaaaga taaagatgta gatttagtaa taggaccaga agcaagagga tttttgatgg
    10441 gtacacctgt agcatatgct ttaggagtag gatttgttcc aattagaaaa cctggaaagt
    10501 taccaggtga agttgagagt tatgagtatg gattagagta tggtacagat actttagaga
    10561 tacataagga tgcaattaaa aagggtcaaa aagtagcaat agtagatgat ttattggcta
    10621 ctggtggaac tatggaagcc gctgccaagc ttgtagaaaa attaggtgga gaagtagttt
    10681 ctatgcaatt tttgattgag ctaaaattct taaatgggag agaaaagttg tctaactatg
    10741 atgttaattc tcttataaaa tactagtact tttataatag ttggtataac accaactatt
    10801 ttcatatata ttaaaatttt atacaaaata ggtggttata tgcatgataa agaattacaa
    10861 gaaataattg aaaaaataaa agtttatgca cctaatgcaa attttgaaat ggttgaaaaa
    10921 gcctataatc ttgcaaaaaa agcgcatgaa ggacaatata gaaaatctgg ggaaccatac
    10981 tttattcatc cattagcagt tgcaaatatt ttaatagaga tggaattaga tattgaaact
    11041 ataacagcag gtttacttca tgatgttgta gaagatacag aatataccta tgaagacata
    11101 aaaaaagaat ttggcaaaga agtagcggat ttggttgatg gagtaactaa acttggtcaa
    11161 ataaaatatc gttcgaaaga agaaactcaa tctgaaaatt taagaaaaat gtttttggca
    11221 atggcgaagg atataagggt tatacttata aaacttgctg atagattgca caacatgaga
    11281 acattaaaat acatgcctcc agaaaaagca aagtataaag caaaagagac acttgaaatt
    11341 tatggtggta tagctcatag attaggaatt tccaagataa agtgggaact agaagacaga
    11401 gcattaagat ttatggaccc agaagggtat tatgatttag ttagtagagt atcaatgaag
    11461 agaagtcaaa gagaggatta tattcaagga attgttgaac ttcttaaaga taagtttaaa
    11521 gatttaagta taccatgtga tgtatatggt agaccaaagc atttttacag tatatataga
    11581 aagatgcaaa aaaaacataa gacttttgaa gagatttttg atttaacagc agtaaggata
    11641 ttggttgata atgtaaagga ttgctatgca gtacttggta tagttcatac attatggaga
    11701 cctattccag gaagatttaa agattatata gcaatgccaa aacccaatat gtatcaatca
    11761 ttacacacca ctgttgtagg tcctgatgga gaacctttag agatacaaat aagaactcat
    11821 gagatgcata atatagctga aaatggtata gcagcccatt ggaaatataa agaaggtatc
    11881 tctagcaaag agtcaaaggt tgaagaaaaa cttcaatggt tgagacagat gatggagtgg
    11941 gaaaaagatt taaaagaccc acaagagttt atggatgcac ttaaagaaga tgtatttaat
    12001 agtcaagttt atgtatttac gccaaaagga gacgtaattg aattaccagc agaatcaaca
    12061 cctatagatt ttgcctatag agttcataca aatgtaggta ataaatgtgt aggagctaaa
    12121 attgatggaa gaatagttcc tattgattat aagcttcaaa atggtaatat tgtcgaggta
    12181 cttacatcat ctaattctaa tggaccaagt agggattggc ttaatatagt gaagacccca
    12241 aatgcaaaaa gtagaattag acaatttttc aagaaggaaa gaagagaaga aaatgttgac
    12301 cgtggaaata caatattaga aagagaattt aagaagcatg atataccaca aaaagaccct
    12361 cttgttgaaa aatatatggc attagttgct aagaaattta atcagccaag tgttgaggac
    12421 ttaattgcca ctgtaggtta tggtggtata atgtcatctc aagtggtatc taaggtaaaa
    12481 gacctatatt taaaagaggt taaaaaagct aaaaaggaac aacagataca agaagaagat
    12541 ttaaataaac acaatataag tgaaacagaa tacagtaaaa agagaaagaa aaacgcatca
    12601 caaggaatta tagtaaaagg gcttgacaat atcttagtaa gatttgctaa gtgttgtaat
    12661 cctcttccag gagatgaaat tgtaggatat attactaagg gtaggggagt agccatacac
    12721 agagctgatt gcccaaatgc aaacaataat ggtgatttct tccaaaatag attggtggag
    12781 gtttcatgga gttcagcagg aaaaggtaag tttgaagcgg aaattcaaat aaaagctatt
    12841 gacagaagag gaattgttaa tgaaataact catattgttg caatggataa acttagttta
    12901 aacggaataa atgcaagaaa aggtaaggat agtattgtaa gtataaactt acttgtagag
    12961 gttaatgaca cagaggaatt aaaaattcta atgaaaaaat taaaagcaat tcctggtgta
    13021 gaaagtattt atagaatgac aaattagagt taaaataata gggaggaaac tatgagagca
    13081 gtagtgcaaa gagtatcttc atctaaagtt acagtagatg aaaacactat aggtcaaata
    13141 aataaggggt tactagtatt gttaggagtg actcatgatg ataaatcaag tgatgtagat
    13201 tatatgattg ataaaatatt gaatctgaga atttttgaag atgaaaatga caagatgaat
    13261 ttatctctaa tggatatagg tggagagctt ttagtagtat ctcaatttac tttatatgga
    13321 gattgcagaa aaggaagaag acctggattt agtaatgcag ctagaccaga acttgcaaat
    13381 aacctttatg aagaatttgt aaaaaaagca aaagataaag gtgtgacagt tggtacaggt
    13441 caatttgcag ctcatatgat ggtagagtta actaatgatg gtccagtaac aatactatta
    13501 gactcaagta aatcttttta agggggaaaa ctttaatgat tataaaaaaa tttgtagata
    13561 gttattttgg agtaaatact tatgtattag gtgatgaaaa gactaaaaaa tgtgcagtta
    13621 tagacccagg tggaagttta gtagagacat taagttttgt aaaagaaaat gaattaaata
    13681 ttgaatatat tatccttact catgggcatg gagaccatat aggatatgtt aaggatatta
    13741 aagaaaaaac tggtgctaaa gtagttgcac atgttgatga aaaagaatta ttaaatgaca
    13801 aaaataaaaa tctaagttat acaatgagat gtggagcgca agagtttgat gcagatatct
    13861 atgtaaatga taaagacaag cttgaacttg gtgaattaaa aatgactttc ttgcatactc
    13921 caggacatac tcaaggatgt atgtgtataa gagttgaaga tgaaatgttc acaggagata
    13981 ctttgtttgc tggaagtatt ggtagaactg atttatatag tggagacttt aaccaaatgg
    14041 aaaaatcact taagaaatta tgtaaatatg aagatgctgt tagagtatat cctggacatg
    14101 gaccaaccag tactctaggg gttgaaaaga agacaaatcc ttacatgtaa ttttatatta
    14161 gtatttaaaa aagtataaaa tatttaataa ctatattagt gagggggttc ttctactgtt
    14221 aaatagaagg agttaagttg atgttgtatg tttttttaaa aggacatgat tataagtatg
    14281 aagtagcaga atttataaaa ttgtttacta gtgaatttaa gtttaaagac tctaatgcta
    14341 acaataatat agagtcaaag catttaataa atagattgat ttatgagaat ggtgtattat
    14401 tctcaagtac tgaatactat gaaaatggaa acttaaagta cgagtcaata cagaatatag
    14461 aaaatatgaa tcttgaattt ttagatggat ttgatagcag caaaacgatt gaagaatttc
    14521 ttaatagcct agatagtgaa agtaagagga actttaaaaa gctgtgtaaa gaaaatatca
    14581 aaaaaagcat gtttttagtg cttaaacaag tatttaattc ttatgtacca tggggaattt
    14641 tgactggtat tagaccagtc aaaattgtcc acaatttaat ggataaaaag ctagatgata
    14701 atagcataag aaccattcta aaagataatt attttataat agatgagaaa atagatttag
    14761 ctcttgaaat agctaaaaga gagcgattat ttatgtatcc tatagataaa aataaaattt
    14821 ctctttatgt aagtattcca ttttgtccaa ctagatgtgt atattgttca tttccttcaa
    14881 attcattaaa acaatttgga catttaaaaa gagaatatgt ttataaattg attgaagaaa
    14941 ttaaggggtt tgccaaagtt attaaggata ctaagaaaga agttgaaact ctatatattg
    15001 gtggtggaac tccaactaca cttgatgagg aagaattgga tttgcttata aattcattgt
    15061 tcaatgaatt agatttaagt aaaattaaag aatttactgt agaagcaggt agacctgaca
    15121 ctattacaga acaaaaacta agagtgttaa aaaaacacaa tgttagtaga attagtataa
    15181 atcctcaaac tatgaatgat gataccttgg taaagattgg aagagagcat agagtatctg
    15241 atttagtaga ttgctttaat atggctcgta gaatgggatt tgataatata aatatggata
    15301 taattttagg tcttatagat gaagacttaa atatggtaaa gaacacattg gaggagataa
    15361 aaaaactttc tcctgaaagc cttacagttc atacattagc cataaagaga gcatctaact
    15421 taaatataaa tatggatagg tataaagaac atctaacaca atatgaagaa atggtaaaaa
    15481 tgatagattt atcaatgaaa tatgcaaaag atatgggatt aaatccatat tatatgtaca
    15541 gacaaaaaca tatgttggga aatttagaaa atataggtta tgctaaagaa ggatatgagt
    15601 gcatttataa tatacagatt atggaagaaa aacaaagtaa ctatgcatta ggtgcaggtg
    15661 ctatatcgaa atttgtctat gtagatgaag atagaattga aagagtagaa aatgtaaaaa
    15721 atgttgaaca atacattgaa agagtagatg aaatgataaa aaggaagaaa gaagaggtat
    15781 ataaaaatgt tgactaaagc tcctagagga actaaagaca taactccaaa agaggcttac
    15841 aaatggcgtt atgtagaaaa taaatttaga gaaatatgtg ctttatatgg atatgaagaa
    15901 atggtaacac ctatatttga acatacagaa cttttcaaga gaagtgttgg agatactaca
    15961 gatatagttc aaaaagaaat gtattctttt aaagataaag gtgatagaga aattacccta
    16021 aagccagaag gtacagcagg tgtagtaaga gcatttatag aaaataaatt atatgcagat
    16081 actcaaccaa caaaattatt ttatgtgaca ccttgtttta gatatgaaag accacaagct
    16141 ggtagacaaa gacaatttca ccaatttgga atagaagcac ttggaagtga tactccttca
    16201 atggatgctg aaataatcgc actagctgtt caatttttta atgaagttgg attaaatgat
    16261 ttggtagtga gtataaattc agttggctgt ccagtttgta gaaaagagta caatgcttta
    16321 ttaaaagagt atcttgactc aaaagctgat atattgtgtg atacttgcaa tgagagaaga
    16381 gaaaaaaatc caatgagggt tatagactgt aaaaatccta catgtaaaga aaatatcaaa
    16441 gatataccat ttattgcaga ccatttgtgt gatgattgta aatctcactt tgataaactt
    16501 caagaatact taaaggaaat gaatataaac tttgtaattg ataaaacaat agttagaggc
    16561 ttagattact atagaaaaac tgcttttgaa attatatcta atgatatagg agctcaaagt
    16621 actgtatgtg gtggaggaag atatgatggt cttgttgaac aattaggagg accaaaaggt
    16681 ataagtggaa ttgggtttgg actaggaatt gaaagacttt tacttacact tgaaggtaat
    16741 ggaattgaaa tagaaaaccc tcaatctacg gatatattta tagtaactat aggtgaagaa
    16801 gcaaatacaa gaagctttaa attgttaaaa gacttgagac aaaatcatat aagtgcagat
    16861 aaagaccata tagagagaag tgttaaagca caatttaaat attcagataa aataaattca
    16921 aaatttacaa tagtaattgg agatgatgag cttaaaaatg acactgcgac attaaaaaat
    16981 atgaaaacat cagagcaaac tactgtaaaa ttaagtacat tagttgaaga attaaagcaa
    17041 aagctgtaaa ataagaaagt atgatgtttt gtgtattaga taaatatata gcattaaaat
    17101 taaataaaat ggaggtagta tcttggaaac tttaaagggt ttaaagagaa ctcactactg
    17161 tggagagttg agagaaaaaa acataaatga agaagtcgta cttatgggat gggtacagaa
    17221 aaaaagaaat ttaggtggtc ttgtatttgt tgatttaaga gatacaagtg gattatgtca
    17281 aatagttttt gatacagatg tagataaaga agcttttgaa aaagctgaaa aattaggggc
    17341 tgaatttgta atagctgtaa aaggaaaagt atgcgaaaga caatctaaaa accctaatat
    17401 gctaactggt gatatagaaa tatttgcaac tgaacttaga cttttaaaca agtcagaaac
    17461 tccgcctatt tatataaaag atgatgatga tgtttctgaa gcactaagat taaaatatag
    17521 atacttagat ttaagaaaac catctatgca aagaaattta aaattaagac ataaagtaat
    17581 gaatattaca agaaattact tatcaaacaa tagattttgc gaaatagaaa caccattttt
    17641 aatagctcca acaccagaag gagcaagaga ttatctagta ccaagtagag ttaatccagg
    17701 aaaattttac gcattaccac aatcaccaca attatataaa caattattga tggtaagtgg
    17761 tatggataga tatttccaaa tagttaaatg ctttagagat gaagacttaa gagcagatag
    17821 acaaccagag tttacacaaa tagactgcga aatgtctttt gttgagcaag aagatgttat
    17881 gagtatgatt gaaggtttgc ttgaagcgat atttaaagaa gttttagatg tagaattggc
    17941 acttccactt cctaagatga cttatgcaga agctatgtct aaatatggtt cagataaacc
    18001 agatactaga tttggatatg agttaacaga tatatctgat gttgtttgta actgtggatt
    18061 taaagtgttt gctgatgcta cacaaccagg aaaaagtgtt agaggtataa acgtaaaagg
    18121 caaagctgac gactttacta gaaaacaaat atcatcacta gaagaacatg ctaagacata
    18181 tagagcaaaa ggtcttgctt ggatgaaagt aggacaagaa ggagtaactt ctccaatagc
    18241 aaaattcttt aatgaagaag aaatgaacgc tatacttaca agaatgaatg ctgaagtagg
    18301 agatttactt ttatttgtag ctgataaaaa ctcaatagta tttgatgctt taggacaagt
    18361 tagacttgaa gtagcaaata ggcttaatct attggataaa aatgtatata acttactatg
    18421 ggtaactgag ttcccagttt ttgaagaaga tgaagaaaca ggcacattct cagcaatgca
    18481 tcacccattt acatcaccta tggatgaaga tttagacaag ttagaagaag gtgataagtc
    18541 atctttaaga gcgaaagctt atgatattgt attgaatggt tatgaaatag gtggaggaag
    18601 tgttagaata tcaaattctg atgttcaatc aagaatgttt aaagcacttg gttttacaga
    18661 ggaaagagct aatgaaaagt ttggttattt attagaagca tttaaatatg gtactcctcc
    18721 tcatgctggt ctagcttttg gtcttgatag acttgttatg ttacttgcag gaactgataa
    18781 tataagagaa gttattgcat tccctaaaaa tcaaaatgct gtttgcccta tgacaaatgc
    18841 tcctacattg gcggaagatg agcaattaga agaattaagt ataaaagttg atataaaaga
    18901 taatgaataa tatgtagttg caagaaacta aaatgtaaaa agtctggata taaaatatat
    18961 ttatattcag acttttttta ttagaattat tttatatttt ttctctatat attttcataa
    19021 attatactta tattcttaac caatataatt aaaatactat gtttaaaaat tttacataaa
    19081 cttgattatt ttagaaacta cttctgtaat gagtacacga ttttaattaa agaatatata
    19141 acaaatttga aataagtcta atatatgact taatagatta aattaaaata ataaatttgg
    19201 actatttatc tatttataac ttaaattata tcaaattgat aacaaactag atattatact
    19261 tttttgtaga atagaattac aattatataa agaaaaattc tattaatagt gaaaaaaaag
    19321 tagaaaaaag tagaaattat tcttttataa agaaagggag ggataatatt gcaagagaga
    19381 gaagaattag ttttaaatcc agttccaaaa gaggaaagag ttggatggtt agctccattg
    19441 tttaatatgc ttggttctaa catagctata tctgaactaa tggttggagg aactttaatt
    19501 ttaggaatga ctctttctaa tatgattatt acatcaatta tagggaactt aatattagtt
    19561 gcaattatta tgatacaagg ttatataggt tacaaagaag ggttaaatac gtatgtatta
    19621 gctaaggggg catttggaga gataggagga aagtatctta tatctctatt acttggtata
    19681 actagttttg gatggtttgg tgtacaagca ggggttgcag gactatcagt acaaaagata
    19741 tttccaagtg taaatctaac attagttaca gttatacttg gattatttat ggttgttttt
    19801 gcactgtatg gctttaaagc tatggctaaa tttaattact tagttatacc accacttatg
    19861 atattaatgg tgtggggagt ttttaaagct ttttctactt atggagttga agctatttat
    19921 aattatactc ctcaaacaac tatgagtatg gttgaaggtc ttaatattgt agtaggtctt
    19981 gttatagttg gtgcaattat atcacctgac cagttaagat atacgagacg agtaaaagat
    20041 atttggatta tcagtttttt aggtctaggg attatttcat tattccaaca agttgcagct
    20101 ggtgtaatgt ctatgggagc acctacttgg gatataacag aagtattggc taatttaggt
    20161 tttggatggg tagcgtttgt tattttaata cttgcatctt ggtctacaaa cgtatcaaat
    20221 gcttattctg gtggattagc attaaaaact atttttccaa atgtaaaaag aaatgttttg
    20281 actttagttg caggtctaat aggtacaata atagcagcta ctggtataat atttaaattt
    20341 cagtcatttt tatctttctt gggaatcgca gttcctgcaa tagctggaat tatgtggtgt
    20401 gagtattatt ttatacaagg aagaacttat aagcatagag aaggaataaa ttggattgca
    20461 gtaataagct ggttaatagg ttttgcagcg tcgtattata gttcaaaaat aaatttctta
    20521 atacctccga taaatggaat tgtagtgagt atggttattt attatatatt aatgaaatgt
    20581 tttggaatca aagataaata aagggggcaa ttacatgggt cgtaaggtga aaataggtat
    20641 aattcaacaa cacagtgtac ttggagatgt taaaaaaaat atagaaaagg cagtagagat
    20701 gatagatgac ttaggaaaac aaggggcaga tataatttgt ttaccagaac tatttgctac
    20761 aggatataat ttagagtctt taggtggagt taaaacatta gaattaataa gagaacataa
    20821 taagtacata gaggaatcaa tgtcagaagc tgctaaaaga aataatgtat acctgatatc
    20881 tccatatgga accttagaaa aagggtctac acatgtttat aattcagcag ttatatttga
    20941 tagaaaaggt aagattatgg gagaatactg taaaaatcat ctgtggtcat tagaagcagt
    21001 atactttaaa ggaggggaaa aagtagaggt atatgatgct gattttggta gatttggtgt
    21061 aatgatatgt tatgatgcag gttttccaga agtatccaga gaattgacat taaaaggttc
    21121 tgaaataata tttataccat ctgcatggag aatacaagat gaagatatgt gggatttaaa
    21181 tgtatctcaa agagctttag agaacactgt atatacagta ggtgtaaatt tagtaagtaa
    21241 tgactctaat ttaatactat ttggaaagag taaaatatgc aatcctagag gtactgtaat
    21301 aactcaatta gatacataca gggaaaaata tgtattatca gagattgatt tagatgaaat
    21361 aaaaaagtat agggaagata tcccctattt gaaagacaga aaaagtagct ataacatata
    21421 attctatact ataatacaag ttcaatataa aatgataaaa agaggatgta tcaatattaa
    21481 gattaaattt attatacttt gatatatcct ctttaatatt atcaactttg atttaaatat
    21541 ttttaaaata gttgataaga aagtttttga acaacaacac agctttagat tcatagtttt
    21601 cgctaaacca tgaaagattt aaatatcttt taaattcaat atctttgata tgtaacaact
    21661 taatctcagg gtcttgagat aatccccatg attttccaca tataaatcca actccttgaa
    21721 gtgattttat aagagcataa attgtatatg gtgaatcaga ctcaaatgct attttgggtt
    21781 tgaaattagc tgattcgcac aggatatcaa ttacctctct ataattctca cccttcgtta
    21841 taactataaa gttttcatct gaaacttcgc ttagatatac ttcatccttt aatgataaag
    21901 gatggtttat tgaaactcct aatagtattt cttcgcatgt taaagttatg ctattttctg
    21961 agtttagctt tgtaaatgaa gaagatatgt acaaatcaaa atcacttttt ttataagatg
    22021 atggcaaagt atgtgacaca ttaaaagtaa tattgggata tagttttctg aaattactca
    22081 aaagtgatgg taacacatta gccgctgcag gagataatat ctttacttct cctgaatttt
    22141 ctaaagaagt gtcttgtaac tccttttttg aactttctac taaatctaaa atgctatcta
    22201 ctctttttag aaacaatctt ccatactcat ttaaaacaat atatcttcct tttctgtcaa
    22261 ataactgaac tccaagttct ttttctaagg aagatatagt tttgcttaaa gctggctgtg
    22321 ctatatttaa cttgtgtgat gcttttgtta tgtgctccat tctagcaaca gtttgaaaat
    22381 acttaagatg caataaatcc atagtataaa atacacctct tttaatatga cttgagttat
    22441 atcaatttta taatcaactc cacattatac attataatat aaagtttata taataaacta
    22501 caatatatta aaaagttatt taaattgtta tttatatttt gtacataatc taattaaaaa
    22561 aagtaacttt aaatgattaa ctaaggaaat gttgttacaa actttagtta tataaaaaat
    22621 tcatttgatg agcaaagtac taatatcaag taagaataaa agcttattag ataagaaaaa
    22681 taatatttta taataatgat gttacttaaa ttattatgtt atactatttt aaataggaaa
    22741 aatttagata ctataatttt agggggagtc aagatgaaat taactaaatc aatatcatca
    22801 atgctgtgct tatctctagt tttaagctta tcaccagtag catatgcaaa tgaaataagt
    22861 agaacaacag ttgagaatac tttagtaggt caggatagat atcaaactgc tgttgaagta
    22921 agtaaaaaag gatggagtag tgcaaatgag gctgtagttg taaatagtga atctattgta
    22981 gatgcattag ctgtaacacc atttgctaaa ttaaaaaatg ctcctatatt attgacagaa
    23041 aaaaataatc taaattcaca aactgagaaa gaattaaaaa gattaggagt taaaaaagtt
    23101 tatataattg gtctatctag ttctgtatca aatgatgtgc aaaaacagtt agaatctaat
    23161 aatttaacta ctgatagagt tggtggtagt gatagatacc aaacagcttt gagtatagct
    23221 aaaaaaatag aaggattaaa agatatatca gaaatagctg tagtaaatgg gtacacaggt
    23281 cttgcagatg cagttagtat aggttctgta gctgctacta atggaatggt tatacttcca
    23341 gtatctgatg catctggtat atctagcttt aaagatttta tagaatctaa gaatataaat
    23401 aaatcataca taataggctc tactaatgct gtatcagata aaataaaaca aagtttacct
    23461 aattcagaaa gaataggtgg agcagataga aatgaaacta atggtaaagt aatagaaaag
    23521 ttttatacat ctaataaatt aaacaatgta tttgtggcta aggatggaat gaaaaatcaa
    23581 aatcaactta tagacgctct agcagtagga gtactagcat caaaagaaaa ttctcctgta
    23641 ctaatcgtag gagaacaatt aagtgcaaca caaaagagtg tattttcgaa taaaaatgct
    23701 acctctataa ctcaagttgg tagtggagga aatgaaaatg catttaaaga attaaaagat
    23761 ttacaggcaa atagtaacaa taagagagta atgtatgtaa ctaatacaga taaggtaaat
    23821 ataagaaatg atgctacaat agaagcttct gttataggat atctaaataa tggtgatgaa
    23881 gtagaagttt tagatgtgtt aaaaactgga tgggtaaaaa taaaatacaa tgaaggtatt
    23941 ggatatgtta gtgggtctta tttgacaaat aataagcctg ataatagtaa tgaaaatata
    24001 aaaataaagt atgtaaaaga aaaagatggt ctaaatgtta ggaaaggacc aagtacagaa
    24061 gatgaaaaaa taggtcacct ttcatatgga agcaaagtag aaacaataga aatgtttgct
    24121 actggatggg taaaaataaa gtacaatggt ggatatggtt atgtaagtaa tgattactta
    24181 tctgatacac cagttattta attataagta acaataaaaa aactgcttta atttgtaaag
    24241 cagttttttt ataaaaattt aagtctaata actatttcta ttttgatacc ttaatcctgg
    24301 gatttattat tatggatatt atcaacatac aaacactcca aatccagtgt ctaattccaa
    24361 acttagatat taataaattc agtcctgcta tggtaaataa gcagtattta attacaatta
    24421 aaagtgtatt tatagaaagc cccctcatag aaagtatcct aaatccaata atagacattc
    24481 taagtcctat aaatgccaat aatatacctg caatatcctg aattaagtaa tagtattcaa
    24541 atttcatatt caatcaactc ttctctgagc agtatcaaat atttctaact cttcaatttc
    24601 atcatctgtg tatgtaagca tagtaaaacc agttacacca taaataaatg aaattatagg
    24661 tgtaatccaa cttaagaaac aatatggaat aaattctagt ggacttacac caagagtctg
    24721 agcacagaaa acagcatttg aattccatgg tattaatgga ccaccaagtg tagctgtatc
    24781 ttctataatt ctagatagat tttgtggttt taatttaaat tctttgtata ttggagacat
    24841 tagagttccg acaaatacag aagtgaacat cattgatgaa ctaaatgcat ttgcaaagta
    24901 gcttactata aaagtagacc caaccaattt agttcttgat tttcctattt tagttataag
    24961 aggttgaagc agtacttcta agaatccagt tttttggaga ataccagcaa taacgaaaac
    25021 tacaaatact agtaaaacgg tttcagccat actcattatt ccaccacgat ttaatagttt
    25081 gtcggcatag acaaatccag tatctatagt aaatcctgat agcatgtaat ttaaaacatc
    25141 acctattttt tctccttctt gaaatactgc tataataagt cccatgatag ctgaacttag
    25201 tatagatata atgggtggct tttgtagcaa taaaagtaat aataaaaata ttattggaat
    25261 cattgctact aaaccaatat gaaagtttga atttaataca tccttgattt gatttatttg
    25321 aacatagtct atagtattat ttgaatactt aaatccaatt actgtataca gaactataca
    25381 tattacgtat gcaggtcctg tggtataaaa catatgcttc atatgtgtaa ttacatctgt
    25441 cttacaaact gctgcagcta agtttgtaga atctgataga ggtgacatct tatctccaaa
    25501 gaaagcacca gaaatgactg caccagctgt taaaccaaga ggaataccca tactagtacc
    25561 aatactcatc attgctatac cagaagttcc aagagtcccc caagatgtac cagtagcaac
    25621 agaagttaat gaacatacga ttaatgttgt aagcagaaaa tatttagggg ttattattgt
    25681 tagtccacta tatactactg ttggtattgt accagcagct atccaagctg ctattagtac
    25741 accaacagaa agtataatta agtttgattg aaaggcatct ttgccaactt caaatccaaa
    25801 agcttctatt tcatcattag tataaccaag tttcatggct gcaggaacta ctataagcca
    25861 tgaaagtaaa aacattgtag ttatagaagc attaaataca actataccaa ctgatgttag
    25921 agctattatt gcaagcatta ctaacaagga atatctaaat gaaggtattt ttctttctgt
    25981 attcattttc atagtgcaaa ttctccttaa atatttttag ttaattgcat tttttattct
    26041 tataagagct tcttcaagca tacttcttgg acaagctaag tttattcttt gatacccact
    26101 tcctccaatg ccaaagctgt ttccttgatt tagagcaact ttaccttttt gtacaagtat
    26161 actttctagt tcctcatcac ttaatccaag tgcactaaag tctacccata ataaataagt
    26221 accttctggt tttctaactt taagttttgg catattttca tttatatatt ttatagcaaa
    26281 atctatatta gattctaaat attctaaaaa tgattctagc caagattcac cattattata
    26341 tgaagcttca gttgcaacta agctaaagca attatttctc tttatatcaa ttctggtaaa
    26401 ggcatcatct aacaatttat agtatttttc atcaggtagt attacatatg atgattgaag
    26461 accagctata ttaaaagttt tagttggagc catacaagta attgtatttt tttcaaattc
    26521 tttagaaata gatgccatag gaatatgctt atgttttttt aatataatgt cactatgtat
    26581 ttcatcagat atgattttta cattatgctt aagacaaata tctcctagtt tttttaattc
    26641 atcttttgtc catactctac caactggatt atgaggatta caaagtatga ataattttac
    26701 atctttaatc ttgttttcaa tgtcttcata atccattatg tagtttccat tttctaattt
    26761 ttgtaatggg cttataatta gttctctatt gttatttttt acaacactat taaaagggct
    26821 gtaaactggt tcttgtatca ttattttatc atttgctttt gtgagttcat ttattaaaag
    26881 acttatagct gggataacac ctggactata aattaaccac tcacttttta ttttccagtt
    26941 atgtctccta tctagccagt ttactataga ttcattgtaa gaatctggtc ttgttgtgta
    27001 gccataaatc tcttgttcta gtctattttt taaagaatca attatacaag gtgcagcctt
    27061 aaaatccatg tcagccaccc acataggaag taaatcatta gttccatact ttttttccat
    27121 ttctgaccat ttagatgaaa aattattgct tctatcaaca atctcattaa aattataatt
    27181 cattgtaaat acctccagta attttaattt tatgttaata atattaagca aacaacgtgc
    27241 caatattgat aataaaaaat atttattcac aagttaatat ttaatattaa gtaatttcag
    27301 agcatagata agataaaaat attaattata cttaaaactt tgtggaaaag gttatttcta
    27361 ataaattttt aaatatatga aaatgtaatt aaataggtta aataggttta actgtttaac
    27421 ttgttagacc tatttatatt ttttagaaac tctactccct ttgatgttat aattgaacct
    27481 ccacgaccaa caagtatgtc tacaagccca aagtcttgta gttctaaaag catatttcta
    27541 atctgttgtt ctgtcaaaaa tctattttcc tctaaagcta ttttacataa gctttttcta
    27601 cctattcttt cttttaaatc ataagccttt tttaaattat ccaatataaa tatgtattca
    27661 tctagtgacc ttttaaaatt atagtcgtat ttcatgatgt ttttgtcttt gccaatgttg
    27721 aattgatact tttttatatt attacttact ttattacaaa cggttctact ataatttgaa
    27781 tctatagtat ctaatatata ttcaggtaaa tcacatattt ctataatatc tttttccaag
    27841 taacagaaat attctcctaa gtttcttaat tctcttacat ttccttccca tctatacatt
    27901 ttaaagattt cttttacttc ctcacttaga ataaaattac atggaatatc atattttaat
    27961 gaaccaaaaa tttcaaatat atcagcaggt ctttccctaa gtggatgtat tttaagggga
    28021 agaacattca acctaaaata taaatctctt ctaaacatat ttttagatac aagttctttt
    28081 aaatttctat tagtagctgc aattattctt acatcaatgt caatgacatt attagaacca
    28141 atacgtcgta cttgtttttc ttgtatgact ctaagtaatt tagattgaga atttaaatcc
    28201 atttctccaa tttcgtctaa aaatatagtt ccattgttgg ctaattcaaa taaaccaatt
    28261 ttcccacctt ttttagcacc agtaaaagcc ccttcatcat agccaaataa ttcactttgc
    28321 agtagatttt cttgaaaagt actacaattt actgcgacaa aaggatcatc ttttctccta
    28381 gaagcactat gaatggattg agcaaataat tctttaccag taccactttc accaattata
    28441 aggatagatg aatttgattg agccatttta ttagcaattt tttttgtatt aatagtttgt
    28501 atactagaac ctaatatatc atcaaatgtg tatttactga tattaccaga gtttactagt
    28561 tgtgctctta atttagcttg ctttttttct aattgagaaa actttgtcat ctttagtata
    28621 aatccatcaa atacatttaa ttgtatatgt ttaatctcta aatttatatc aatatgattt
    28681 attttaatca atttctcaaa aaatggagtt ttattggtca atatgctttg aaaattgatg
    28741 tcttttatgc aatcaccaac aaatgagtca atcatttcat ttgcatttat agacaaaatt
    28801 tttctagcca tatgattata gaattgaatt attccatcgt tatttgtgca tataattcca
    28861 tcatcaatta tagatagtaa caaatcaaat tgtctttcaa acttatttgc atctaacaat
    28921 aactcacctg tactataact tgtaggaatt attttttcta cgtatttttt tattaggtca
    28981 tcttttatta gatgttttaa tttggttttt gtagcaattt caacaataca acttaaatct
    29041 attattctgt attttaaatc tataacttca caatttttaa acttaggcaa gattttttcg
    29101 ccaggagtta ggattacagc atctgtggga gtaaactcaa tctctggata gcagggcagg
    29161 atatttatat tgtctattcc taatctatgt attaaagaaa ttgtttctat tgccatatct
    29221 ttacttaagt tatatacata aataatttta tctttttcta atttggatat catatcaata
    29281 ctgttctttt caaatgtcaa cttaggaaca atgatttgag catcatagtg agataatttt
    29341 actatttcat catattttaa ataagcagat aggagtataa gtttttcttt aaaaaacttt
    29401 aaatttcctt cttcaaatga gtataaattt atctttagat tatcacctaa gaattgtctt
    29461 atttgatttt cataaatttc tccagcgtct ttttttaaac ttacaatagc taattccatt
    29521 tgtttcattt taacctctca tacaaatttg acttatttta gattacataa taattaaatt
    29581 agattaaata atattattta attattatta taaatttatt atagactaca cattgaagta
    29641 aaagaagtag ctaaaattat tccttttatt tttgtttttt gtatctattt ggtataatag
    29701 tattagagcg tataataatt taggcaaaat tttttaagga agactagagg agaatataaa
    29761 atgaaaaaat gtctttactg taatagggat ataaagtcac caaataataa attagctata
    29821 aaatatgatg acaatatgaa tatatatcca tgtcgtgcag aatgtaagga aaaaattgaa
    29881 gaatatatag caaaaaaacc tacatataag tttataaata tattagaggt tcttttaggt
    29941 gtgggcggaa tattctgctt tttgagtaaa tggactattg cagcccaagt tgtacttgga
    30001 attgatgcac tggttatatt tttattccca ttggcaggat ttaagatgaa tggaaagtta
    30061 agtatggaac aaactaagaa tcaaagtagg tctattgcaa tatcaatttt ggcatttata
    30121 gtaataataa ctgtattata ttttaaacaa attggtaagt agagcataat tgtataagac
    30181 atcattagag tatgaggtga gtttatggaa gaaagaaaat tagcaccaaa caatgagagg
    30241 gaagctctca taaaaagatt aaaaagaata gaaggtcaag ttaagggtat acaaaagatg
    30301 gtggaacaag aacgttattg tgttgatata ttggttcaaa tatctgctat aaggtctgct
    30361 ataaatagag taggcacaat tatcttagag aatcatataa aaggatgtgt agcagaaagc
    30421 attaaacatg atgatgctga taaaactgaa gagatgataa aagagcttat ggatactata
    30481 aataaattta caaaataagg aggcggttag ttatgaatca acaaggattt attatggaaa
    30541 ttgttgatga tagaactgca aagttaaaaa tgcaaagaca ttcagcttgt gctgcttgtg
    30601 gaaaatgtgc tactacaaat tcagcagagt caaaagaaat attagtagaa gtagacaaca
    30661 caattggcgc aaaagttggt gaccatgtag aagtgagtat ggataatatg aatgtattaa
    30721 aagcagctgt aatggcttat ataatacctc ttatagcact tcttgtagga acaataggga
    30781 cttattatat attgggggca attggaatga caactggagt tgaagccata agtggattag
    30841 ttggaatttg tcttacaata atctgttatt tatacttaaa gaagaatgac aaaaaattta
    30901 gagacagtag agaatttata ccagtaataa caagaatatt aattgacctt taagataatt
    30961 ataattaaaa aatagcaatg tgcttcttaa ataaatactc aatacgtatt tgtagagttt
    31021 aagtacattg ctatttttat atttttattt tgattttctg taaggaataa agttttttct
    31081 gattttcaaa agattcaatg ttcttacaaa agaagttaca actaatacac caagtgctat
    31141 tgcagcactt agaaatagcg catctgtacc ttttgacata gccaaagaat aatttttctg
    31201 aatcaaagac aacattgtat tatatagccc aattcctggt attagaggaa gaatacctgg
    31261 aattacgaac acaatagctg gttgctttag ttttcttgct aaagtctcac tgcacgctga
    31321 gaccaaagca gcagcgataa aacctgcaaa aactgcattt gtagtaaaat taaataaata
    31381 aacatataca atccaaccaa ttccgccagt tactccagct ggaagaagta gatatagtgg
    31441 agcattaaag aaaacagcaa atccagcagt tgcaacacct gaaaataaaa aatgcaaaat
    31501 catagacata tcagtcatta gaaaggacct cctattctat accatgtatc aaggacaaaa
    31561 ccaactccag aagcaattgc aataataatc atagcagcat caaaagcacg agaaattcct
    31621 gatattaaat tccctgatat taaatctcta atagctttta taaaagcaac tcctgggagt
    31681 agtggcatta tagcgccgac tataagcatt ttagggtcat ctaaaatgcc tatttcaact
    31741 agtagaactc ctgaaagtgc aattaaaaaa gaagatacta aacaggaaaa tgcagatatt
    31801 gcacttatct tcatcgtttt atcataagta attgcagcaa agattgctat tataaacgta
    31861 agtataaaat ttaatacata attccctcca agcaaacaag caaaacaagc agatgcaatt
    31921 cctgtacaag agtaaaataa ccataaagga taaggtttta catcttggat ttcataaaga
    31981 cgtgcaatgg cattatcaat atcatactct ttgtcactaa caaattctcg agaaaaactg
    32041 tttaataaag aaatcttatt taagtttata cctcttgatt gaatcgtttt cataaacgaa
    32101 aagccatcaa atttctcatc tgaaataatt attactgtag gagttgtaaa aatatttaca
    32161 tgataaaacc ctcttgacct gcatattcta aggacactgt cttcaaccct agatgtttca
    32221 gctccatttt ttatcatcag ttcccctaca aatagagcta gttttagaat atttttctta
    32281 tattcaagtt cctcattttg attcataaat acacctccaa attaaaaaac gtaatattga
    32341 aattatatca aatttttaag taatattcct taatatctat acaaatatat tatctttttt
    32401 ttgtttcaaa atagtcacat ttaaattata tccaattaaa agaattagac aatattattt
    32461 attatatttt aacttaaaaa taaagaaagt aactatgtta aatatggaaa aatggcaaaa
    32521 cacttgacta ttaattggta aaggactata ataataaatt atcatattga taaaaacgaa
    32581 aattatgaaa tgtctgtaaa aataaaattt aaataataac taggaggagt aatatgtttg
    32641 agaacttgaa aaaagcggac cctgagattt atgaaagtat gaaaagagag ttaaaaagac
    32701 aacaaagaaa tattgaatta atagcatctg aaaacatagt atcagttcca gtaatggaaa
    32761 ctatgggaag tcatcttaca aataagtatg cagaaggtta ctcaggcaaa agatattatg
    32821 gtggatgtga atacatagat gaagttgaaa ctcttgcaat agatagaatc aaaaaaatat
    32881 ttggagcaga acatgctaat gttcaacctc attctggagc aaatgcaaat attggtgtat
    32941 attttgctat gttaaaacca ggtgatgttg ttatgggaat gaatttatct caaggtggac
    33001 atttaactca tggtgctcca gttaatattt ctggtcaata ttataaattt tatgaatatg
    33061 gtatagataa agacagtgga cttatagatt ttgatgaagt tagaaagata gcacatgaag
    33121 taaaacctaa aatgatagtt gcaggagcaa gtgcatatcc tagagaaata gattttaaaa
    33181 agtttagaga gatagctgat gaggttggag cattgcttat ggtagatatg gctcatatag
    33241 caggtcttgt ggctgctggt cttcaccaaa atccatgtga agtggctgat tttgttacaa
    33301 caacaactca caaaacttta agaggacctc gtgggggtgt tattctttgt aaagaaaaat
    33361 atgctaaaga catagacaaa gcaatattcc ctggtattca aggtggacct cttgaacata
    33421 taattgcttc taaggcagtt tgctttaaag aagctttaag tgatgagttt aaagaatatc
    33481 aggtacaagt tgctaaaaat gcaaaagcct tagctgaaga acttattaaa agagatttta
    33541 aattgatttc tggaggtaca gataatcatt taatactatt agatttgact aataaaaata
    33601 taactggtaa agcagcagaa aagagattgg atgatgctta tataacagct aataaaaata
    33661 caattccatt tgacccaaat ggtgctcttg ttacaagtgg aataagactt ggtactccag
    33721 ctgtaactac tagaggtatg aaagaagaag atatggcaat aatcgctgag gctatagacc
    33781 tatgtttaac ttatgatgaa gaatctaagg ctagaacatt ggttgttggt ttaactgaaa
    33841 aatatccttt atatgaagaa tataatatta tggattaatt ataaagaaca actaaataaa
    33901 atacatttaa ataattacaa tgattgtgta tgtatttgaa tatatttaga tataaaaaag
    33961 gtgtctcaaa atgaactttt tagtttatga ggcacttttt tgtatggaat cgaacatatt
    34021 tgtattattt aaataataaa aaatatggtt atctctattt ttagatggtc tctttgtatt
    34081 ttttaattaa aactttaaga tttcttaaga attatactag gtttttctaa agatttaaag
    34141 tctatactta taagtatagt aatcatatga aaagaaaagc tttaacgagg agggaatctt
    34201 atgaaggtat taattcttac aggaaaattt ggtatgggtc attactcagc atcaaattct
    34261 ttaagtgaag atataaaagc aaaatttgat aattcagaaa taataattaa agatatattt
    34321 gagtacatta tgcctaacta ttcagataaa atgtacaaga ctttttctat tcttgtaaat
    34381 cggggaagta gtctttataa tttgttttat aaatgtgctg aaaatggaaa gaaagatata
    34441 aaatttactt tttcagatta ttttttaaat aaattagata cattacttca tgaagtacaa
    34501 ccaacagtag ttatttcaac ttttccattt tgttctcaat tagtatcaag atataaggaa
    34561 aaatataact caaatcttcc tttaataaca tgtataactg atataagtag tcactcagaa
    34621 tggattagta aaaatacaga ctgttattta gtagctagta aatctactaa ggaagaactt
    34681 gtttttaaag gaatagatga atctaagatt aaagttaatg gtattccagt aaaaaaagaa
    34741 tttaaaagaa tagaacatgt aaatcattca actaaaaaaa atattcttat aatgggtgga
    34801 ggattaggat tactgcctaa atcagaacaa ttttacaaag aattaaatag tttagaagga
    34861 gtaaaaacta ctgtaataac tggtaataat aaaaaaatgt actataaact atatggtaga
    34921 tatgaaaata tagaggtagt aggttacacc aatgaagtat ataaatatat gaaagattct
    34981 gaccttatta tttctaagcc aggtggaata acactatttg aaacaattta ttcagaactt
    35041 ccaatattgg catttaatcc atttttacaa caagagatag ataatgctag ttttatatta
    35101 aataatgaaa ttgggagaat acttggtaaa aataaaaaat actatgtaga tgagataaaa
    35161 gatttaattt atgatgatgc tactcttaaa gaaatgagca gtaacatgaa agaattaaaa
    35221 aaacaatttg ataataatac cttagagaat attttatttt cacttgatga acaaggagcg
    35281 tgtagagaat gtatgtagta ggtttaatta tcgttgttgc attgattttt ttagtccatt
    35341 caattatacc tacatactat aataaactat taaataaaga ggtattaaaa aatatggctg
    35401 gagaaaatga aattgcactt acatttgatg atggtccaga taagagatat acagaaaaat
    35461 tactagatgt gttaaaagaa aatgatatac aagctatgtt ttttgtagta gcaaagaatg
    35521 ctgaaaaaga gcctgaaatt ataaaaagaa tgttgagaga aaatcatata gttggtttac
    35581 attcattgga acacagaaat gcatggcttt atagttatag ttatgttaaa aaagatttta
    35641 ttgaaagtac aaatataatg aaaaatttag gtgtagatgt aaactactat cgtccaccat
    35701 ggggtcatac taatatattt tcaaattcat ttgttaaaaa atataatcta aaaatgactt
    35761 tgtgggatgt aatggcagaa gattgggaga aagatagtac agtagacatt attataaaca
    35821 agttaatgag tagaacaaaa gaaaattcta taatttgttt acatgatgca ggtgaaaatt
    35881 caggtggtgc agtaggtgca cctgagcgta ctattgaagc tttaaagata gctattccaa
    35941 aacttaaagc cagtggttta aagttcgtaa caccagaaag gatgtagtta tgataagtaa
    36001 aactgaaaag aaaaataaat gcctaggtag tgtagctttt ttagttttac taatgggcat
    36061 aacaggatat tttgttttta gagggcagtc agttgaatca ttgataaaat cattaaaagg
    36121 tgcaagccct atgtttatac taattggatt tgcaatgatg tttatatatg ttgcctgtga
    36181 aggtataaat atatacttag gtatgaaagc tttaaaccaa aagactactc ttttaaaatg
    36241 tatgggatat gcttttattg gattttattt tagttctatt acgccttcag catcaggtgg
    36301 tcaaccagca caagtttatt atatgaaaaa agacgatata aatatatcat attcttcact
    36361 tatactatta gtcattgttg ttattcacca agtagttata ctggcatata gtggaataat
    36421 gttcattatg gaacgtgagt ttatattaaa taatgtaagt ggtatgaaca ttttactaat
    36481 atatggtgta ataacaaatg ttgctcttgt cattggagta attgcaatta tattttcaaa
    36541 aaaacttgta aacaatttta taatatcaat aacaaattta ttaggtaagt taagaataat
    36601 aaaagatgtt gaaagttcaa gaaaagttat aatatctcaa attgaagagt atgttaaagg
    36661 tgctcaatat ataaagcaga atccaaaact tgtagtccaa attttagtca taactattgt
    36721 acaaataaca tctatgtttt tagttccttt ctttgtatac aaagcttttc atctatcaac
    36781 atatactgta tttgagatat tagcgataca atccttgctt aatattgctg tttcttcatt
    36841 accattgcca ggggctgttg gagcttctga aaatagtttt atgacattat ttaagatatt
    36901 tttccctggt cacttattag ttccggcaat gttacttagt aggggaataa gtttttatgc
    36961 atttgtagct ataagtggat tgatatgtat agtagtacat gtaaaatctt ctgaaaaagt
    37021 aaaagcagtg aaaaaagttg cttatgtaag ataatattat atagattatt tttattaata
    37081 tgtcaatttg tgtgtatatt ttaattaagc tttaaacatg tttacaggag tagaaactat
    37141 taaaacgtgt gacattgcta agcttttgct aataaagtat aatattttat atagtttgaa
    37201 atatttaaga aatatagcaa aaaaaggagc ttggtgatga ataaagagat tccaaaaaaa
    37261 attttagtag ctgatgataa tcctgagatt agggaaatcg tagaaatact tttaactggt
    37321 gaaggttatg aagttattat ggcaacgaat ggagaagaag ctgtaaactt agtagatagt
    37381 acgattgatt tgattatttt ggatgttgta atgcctgtaa aaacaggatt tgttgcatgt
    37441 aatgaaatta gagaaaaaac gacagcacca atattatttt taactgcaaa aactcaagac
    37501 tctgataaag ttattggatt ttcagcagga ggagatgact atttatcaaa gcctttttca
    37561 tattctgaac taatttcaag ggttaagtcg ctacttagac gttattatat ataccaggga
    37621 aaggaaaagg aaagagagcc aaatatatta aaaacaaaag agttatgtgt caatttagat
    37681 actcaagatg ttacactaaa tggagaacct gtgtttttga caactataga atatagtata
    37741 ttaattctta tgttgaaaaa tagaaaaaaa gttttttcgt ctgaaaattt atatgaaact
    37801 atttgggatg agcagtattt ttatacagca aataatacaa taatggttca tattagaaat
    37861 ttaagaaaaa agttagaaaa agaccaaaaa aatccacaat atataaaaac cgcatgggga
    37921 aaggggtatt atattgatta acaaaattaa gccatctaag ttgggagtta tactattgat
    37981 atatgtagta atctcagctg cagtggcttt cattttaaat ataccatttt actctgctgt
    38041 tgaatctata gtaaaagatg tatcagaagg gaaagtatat tttaaaagag aagtaaatca
    38101 acttatggat aattttcaaa cttatgtgaa taacaatggt ataagagcag atgatggaga
    38161 tgatatagca aaatggaata gtgataattg gtttgtttct atgaagatat ataaaggaaa
    38221 taaggttttt tatgatacat tatactatcc taatgaagta cctgataaga gtgaggaaaa
    38281 tgagttttat agcagtccca tggctagaaa ctatgagata caattttctg atattaaagc
    38341 taatatagtt gtagtagctt tatttagatt tagatttcaa aattttatag aagcaatttc
    38401 tattacattt atggcactta catttattat aacattttta ctgttgttta gtagaaagat
    38461 aaagtaccta aggaaaatag aaatgggtat aaagatagta gagagtggca gtttaaagta
    38521 tagaatccca gtaaaaggta atgatgaatt atcatcactt gcatctagta ttaatgagat
    38581 gagtcataca ttggagaatc aacttataaa agaaagggag atgaagaata aaaataaaga
    38641 tatagtaact tcgatatcac atgatgttag aactccatta acgtcagtaa tttgttattt
    38701 agatttgatt aaagaccata aatacaatag tcctgagcaa ttggaacaat acataaaaaa
    38761 tgtaaggtct aaagcatatc aaataaaaga tttaacagat gaccttttta cgcattttgt
    38821 taattctgga gaggaagttt caaaagggta tgaaaaaata aatgctaatg aatttatttt
    38881 tcaattactt ttagatagtt catatacatt ggaggagaaa ggatttcata taacaataga
    38941 aaatgaactt tataaccaat atcatattta tgtagatgtt acacaattta gaaggatatt
    39001 tgataattta tgttctaata taataaaata tgctaggaaa gataagccta tagtattttt
    39061 aattaaagta gaggattcta aattactaat tatacaaaaa aatagagtaa gtaatttttc
    39121 taagaatgta gaaagttttg gaattggtat aaagaattgt gagaaaatag ttgcatatca
    39181 taatggaagc ataaatgtaa attcagatga taaagaattt gctattgaaa tatctattcc
    39241 agcaaaagaa tcataaaaat ttaaattata tattgtgtaa ttgctattat atattgtgta
    39301 attgcttatg taaaattcta tgaagcagga agcatgtgac tttagttatg ggatgttcaa
    39361 tattgtgtac ctctaggcaa gtaacaagtt tacttacaag accatataat attattatct
    39421 taaaaaaagg ggacataata atatggtttt gacaggagca cattatattt acattctatt
    39481 tatggtaatt atattaatta ctatgattat gaaaaaggat acaatagtac catgtatatt
    39541 aggtgttttt tttatgggat tgttctttga aaaaaacatc tttggtgcta taacagcagt
    39601 gtttaactct tttattatat ctttaaatga gttgggtcca attatcttga ttatagctat
    39661 tatggttgca ttatctaaag ccctagaagc caataatgct atacagtata tggtgagacc
    39721 attttcgaga gttataaaaa attctaatac agcatttttt gtaactggat ttgttatgtt
    39781 agttctttct tggtttttct ggccaactcc agctgttgcc ttagttggag ctgtattttt
    39841 acctgttgct atgagagctg ggctaccagc aattggtgtt gcagtagcat taaatttatt
    39901 tggtcatggt cttgccttat ctacagactt tgttattcaa ggagctccaa gtataacagc
    39961 tggtgcagca ggtgttgcag tatcatatgt tataaatgat ggtatgattt tgttttgggt
    40021 gatgggaatc gtaaccatat ctatggcatt ttatacatta aaaagagata ttaacaaagg
    40081 aatgtttaga gaagaactaa aaggttttga aagtgaagaa gtagaagcgt tcaatggaaa
    40141 atctaaaata gcaactattt tagtagcttt gggatttctt gctgatataa ttgctatgta
    40201 tgtatttgac ctaaaaggag gagatgcatc agctcttttg ggtggaacag cagtattttt
    40261 aataataatt ataaatgtta taaattttgg caaagatagt cttgaaaatg tatgtgagaa
    40321 tataattgat ggttttgtgt ttgggataaa aatatttgga gcaattatac caatagcagc
    40381 atttttctat atgggtgaag ttgcaccatt gacaggtgta tttggaaaag tattagcacc
    40441 aggttcacaa ggtttattat cagatatagg catagctctt tctcaaacaa taccacttaa
    40501 taaatttgcc gtatcaggta tagaaactgt agtgggagca ataactgggc ttgatggttc
    40561 tggattttct gggatttcat tagttggttc acttgcctct gtatttggaa ctgctataaa
    40621 tgcaagtgtt ggtgcattag ctgcattagg acaaatcagt ggtatatggg taggtggagg
    40681 ctgtctagtt ccttggggtc ttatttcagc agcggcaatt tgtggggtta gtccaataga
    40741 attggcaaag cgaaactttg tcccagttat aaccggattg gttgtaacaa ccatagtagc
    40801 aatgtttatt atttaataaa tcgaataaat ctttaattgt ataaattaaa aatagatgtg
    40861 tagctataat ttattataat tgttttacta attctaagcc atacatctat ttttattgat
    40921 atttttatta gtattcttta ataaagtaat atttttcatt atattataca taacatctaa
    40981 atataacatc taaaatactg ttatctatat ttaatatctt gccaaatttt ttgatgtttt
    41041 attgccctgt cccaccaaca tatataagct atcacaagtt tttacctata ctatcaccaa
    41101 acaaaaattc taattttaat ttattatttt ataacctata ttatattaac tatattagtt
    41161 tgtagacttt agatgtaatt ataaatatta atactccaag agttcaaatt catatcctag
    41221 ttttcttgca tttgatataa aatcatttaa aatttctgta ctagttttgg aaactgcatg
    41281 tagtaacaag atagaaccat catgtagatt atccattatt ttttgcgttg cttcttcatg
    41341 tgatggttgt ttatcagtat cccagtctct gtatgcaaaa ctccaaaata cagtcttgta
    41401 tcctaaattt ttagtcattg ccaagctttt ttctgagtat tttcccatag gaggtctaaa
    41461 aaatttaacc atatctttcc cagttacatc tttatataac ttttcaacat catataattc
    41521 gtcattaaag ttttttagat tgcttgtttt tgttggcata gatggatggg ttttactatg
    41581 atttccaact atatgtccct cagaaaccat tctttttact aaatctttat tttcttttat
    41641 atatggagct gtaacaaaaa aaactgcttt aacctggttt tgttttagag tgtcgagtat
    41701 ttttgtagtg tatccatttt cataaccttc atcaaatgta agatatagtg ttttttgacc
    41761 atcttttgta ggtccattgt atagggcatc atagtcagaa aatttaaatt caatgtccgt
    41821 atttacttct ggtgttttat gcttattgtt tggtatataa aaccaatcaa gagtagtgtt
    41881 atctaaagaa gatacatcta atttattatt atcattatta gtagtggctt ttgatggttt
    41941 atctgttccg tctgaaacta ttacattgga agtatcttta ccactatcta ttttttcctt
    42001 atcttcttgt aactgtgttt ccttattttg attttcgttt tgattgtttt gtgaatttga
    42061 acatccaaca ataaaaaaaa tagaaataga aagtagtgtt aaataatgca atacttttct
    42121 aaacattttg aagctccttt ctaaattaat aataattgca tataataata attatatgat
    42181 taattacaat tgcatatagt attattataa ttggaaatta ctattaataa tagttatatc
    42241 tttaaaaata aagtcacaat agtatgacaa agggtgaata atcaataaat ttaaaaaaaa
    42301 atgaaaaaaa tagttgacca tattatgaga agatgttatt ataataaatg tgctcaacaa
    42361 gaagtaacaa aataacaagc acaaagaagt taattgaat
//
LOCUS       DAEPHU010000029        41798 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 01A10CD0081
            SAMN05941466-rid12468953.denovo.029, whole genome shotgun sequence.
ACCESSION   DAEPHU010000029 DAEPHU010000000
VERSION     DAEPHU010000029.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941466
            Sequence Read Archive: SRR6291087
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 41798)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 41798)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068158.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 22:43:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,892
            CDSs (total)                      :: 3,805
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 87
            rRNAs                             :: 8, 1, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 55
            CDSs (without protein)            :: 55
            Pseudo Genes (ambiguous residues) :: 0 of 55
            Pseudo Genes (frameshifted)       :: 21 of 55
            Pseudo Genes (incomplete)         :: 28 of 55
            Pseudo Genes (internal stop)      :: 16 of 55
            Pseudo Genes (multiple problems)  :: 8 of 55
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..41798
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941466-rid12468953.denovo.029"
                     /strain="01A10CD0081"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            398..1705
                     /locus_tag="KR231_001671"
     CDS             398..1705
                     /locus_tag="KR231_001671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728608.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0004051.1"
                     /translation="MKEIADAITSEYLSYGINEDISIYEGRFCIYLDKKYRCNGKIYY
                     KMTPPISISFKADIGCVEEIDNEDDNLALDYDNAILEVHGYKIISITINTLSEFSVEG
                     YINDDCIKSKNSYVEYVDFNIINLDKIPGKLIKYNDKVYAGRIEFDINDYVVTIDKRY
                     DYRKELKSELKSKSGAIITHIGRIRRKDGRIFRTNNTINLLDRISTALSFMCGRYVGF
                     CLAKGYRSGNEVYRIWNENQISPFRYVPTWSDTLSNYYNMEKYISLMCKKLEDFYYGS
                     AIKSVVDWYIESLGSATMENNIISVQIALETLSYVILVEQNKILTDEVFDCNLASKNI
                     RLLLDTCKIPYGKHELNIFDNIIKNKFDDGVDLVIYLRNSIVHPSRKTHRAVLEVEDI
                     WNIISIGTRYIELVLLFILGYRGEYSNRLVERCYGEVEVVPWN"
     misc_binding    1791..2053
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            2179..2982
                     /locus_tag="KR231_001672"
     CDS             2179..2982
                     /locus_tag="KR231_001672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HBH0004052.1"
                     /translation="MKNILKKVGIFTIMLGLLGGVVGCSKPDNEKDKDASKESKKEVV
                     VGFDNTFVPMGFLDEKGDTVGFDVDLAKETFKRLGMEVKFQPIDWSMKETELNDSKTV
                     DVLWNGYSITDERKKIVSYTEPYLQNKQIIVTLSDSKINSKADLKDKEVGTQQGSTAL
                     DAVEKDKDFMNSLKGGAPVLYDTYDKALRDLEIGRTSAVVGDEVLIRYYMGQKGEDKY
                     KVLKDDFGLEDYVVATSKENPELCEKINETLKEMKKDGTFDKIYDKWFK"
     gene            3020..3631
                     /locus_tag="KR231_001673"
     CDS             3020..3631
                     /locus_tag="KR231_001673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HBH0004053.1"
                     /translation="MLQGLEIVIAMFCITLIVSIPLGIGVAFLRLSKNKLVSGITQCY
                     ILIMRGTPLLLQMIVIFYGLPLLGIVFDRFTAGVVAFFLNYAAYFAEIFRGGIQSIDR
                     GQYEASKVLGFDKFTMYKRVIFPQVFKRILAPISNEVITLVKDTSLVYILGLNDILRI
                     SQIAMNREASLLPLFEAGAIYLIFVAILTKGFELLEKKYSYYR"
     gene            3663..4334
                     /locus_tag="KR231_001674"
     CDS             3663..4334
                     /locus_tag="KR231_001674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HBH0004054.1"
                     /translation="MLKIKNLNKSFKKNRVLKDISFELEEGQIGVLLGKSGAGKTTIL
                     RCINGLEEFDSGEIIIDNEVIKNKRDMAKIRGKIGMVFQNFNLFPHMTVLENIIESPV
                     NVFKVPRKEAEERARELLRLVDLEDKLNSYPFELSGGQQQRVAIARSCALMPKVLCFD
                     EPTSALDIDTIQRVVNIMNRLKDKGMTILIITHDVVFSNNVADKIISIKDGIVENVQI
                     KEKIV"
     gene            4632..4994
                     /locus_tag="KR231_001675"
     CDS             4632..4994
                     /locus_tag="KR231_001675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase family protein"
                     /protein_id="HBH0004055.1"
                     /translation="MIKLYGYTKCSTVKKAKNWLKENNLEFEDIDMVQNPPSKEELKS
                     IYKTSGYDIKKFFNTSGMKYRELGLKDIVKTESDDKLLEILVSDGMLIKRPLLLDGKN
                     VLLGFKEDVWKSTLLKED"
     gene            5430..6131
                     /locus_tag="KR231_001676"
     CDS             5430..6131
                     /locus_tag="KR231_001676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4253 domain-containing protein"
                     /protein_id="HBH0004056.1"
                     /translation="MSIEDLYDFECVPLNNEIDIDVLFEKMIEDGKEKEYTPIIVIDE
                     KVGLLRKNIDMITKEYGSLENYREYCLTKYNEIDVNQFFDFRKSEISELLKELIDLED
                     DFYDYKHFRPIMNIDIFHEYNKVYIAKIPTIKPYEVFAYIPIGGFNDCPRDEEHIAIA
                     KYWYEKHGIFPIAIGCDTVQYSVKNLTKDGKKFDDLCIELVFYCEDIIIQGYETLKAL
                     KDVLKRSTIVLFWWD"
     gene            6401..7219
                     /gene="larE"
                     /locus_tag="KR231_001677"
     CDS             6401..7219
                     /gene="larE"
                     /locus_tag="KR231_001677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent sacrificial sulfur transferase
                     LarE"
                     /protein_id="HBH0004057.1"
                     /translation="MEVNFVKEKEKLDKLKKMLLELGSVVVAYSGGVDSNFLLKVAKD
                     TLGENVIAVTIHAMMHSSREIEEAKQYTQNFGVKHIILNIENFDLKEFKENGVDRCYH
                     CKKYIFSKIKEVAKEHNIKYIVDGTNIDDLGDYRPGLKALSELGVISPLKDSSLKKEE
                     IRSLSKTLGLNTFNKPSFACLASRIPYGVEITDENLRIVEKSEEYLSNLGFSQFRVRM
                     HGDIARIEVGQEELGKFFENNNFNKVDTKLKIFGFKYVTLDMSGYKMGSMNLNV"
     gene            7274..8422
                     /locus_tag="KR231_001678"
     CDS             7274..8422
                     /locus_tag="KR231_001678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent RNA methyltransferase"
                     /protein_id="HBH0004058.1"
                     /translation="MKNYTLISPCFFGMEKMLAREITNLGYEIIKTEDGRITYKTDEF
                     GIAKSNMWLRCAERVHLKIAEFEAKSFDELFENTKRINWSRYIPYGAQFPISKASSIK
                     SKLYSTPDVQAIVKKAIVESLKKSYLEDGLLKEDKEKYPIFVFIHKDKVTISIDTTGD
                     ALHKRGYREKANKAPIRETLAAGLIYLTPWKAGRVLVDPMCGSGTILIEAAMIGINMA
                     PGLNREFISEKWRTLDKKIWWDVRKDAFNKIDNESKFKIYGYDIDEESIDIARENAEI
                     AGVDEYIEFNVGDATQFKSEDEFGFIITNPPYGERLEDKDSVKQLYKELGYAFRKLKN
                     WSYYLITSYEDFEYEFGQKADKKRKLYNGMLKTNFFQYPGPKPPRNNK"
     gene            8558..9946
                     /locus_tag="KR231_001679"
     CDS             8558..9946
                     /locus_tag="KR231_001679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein"
                     /protein_id="HBH0004059.1"
                     /translation="MKVLKLITVVALMMLFVTGCNIKTESPEQLAKIPDYDDTKKVLY
                     DGIDQLLKPDSSMILPSNTKEVGKINKVDLNSDGIDELVVFEQKEDLSNNVSQVGFVT
                     LSYNGEKYVLGDHFLENGESIEYANFYDLDSDGYKEVILLVKSKDKTNMHIYKVVDNE
                     ITKIYDLDASWLQNKEDFNDMKVKIGYIDGDDKLDILMLHLNNKTNEMFASVANFDGK
                     MKIKDSVKFENVKNLSELYITLGNVASSVGNSSAAIKGIVLDIPILKDNNYITQILYM
                     KDGKINKAFSDYDKTITKSYYIPVDDIDKDKIIEIPIVAGSTGNNKNTYSSKSSATIS
                     WYRWNGKEGADSSLIFTSQIYYNYKYNFKLFIPNNLFDKILVEQEFVGEKAVFKFYYF
                     DYSDRKNLFNIVVESKNKLEDRKNTGTQNSIVLQESDEYTFLLVVNNANEMDKLDMTI
                     DALKEYFSLIYG"
     gene            9975..10673
                     /locus_tag="KR231_001680"
     CDS             9975..10673
                     /locus_tag="KR231_001680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBH0004060.1"
                     /translation="MKEKILILEDEIGIRSFVSINLKREGYEIVEAGTGREAIEKMTT
                     EKDITIALLDVMLPDISGIEVCKFIRENFDQVGIIMLTAKAQEDDKIEGFISGADDYI
                     IKPFSIKELLVRVSALLRRVAKDDSSVKSSEIVSPPFILDIDKRKLFKNGKEIELTPT
                     EFSIVKYLISNAKQSLSRDQILDEVWGTNYLYDFKIVDVNIRRIRNKIEDDPSKPKYI
                     QTIWGYGYCFRKEE"
     gene            10676..12109
                     /locus_tag="KR231_001681"
     CDS             10676..12109
                     /locus_tag="KR231_001681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBH0004061.1"
                     /translation="MLHFEGLRKKVIKNYFIIIIIMVTLFEGLFMFYIQNYYYDSVKQ
                     LLESEIKYADEYNAITMETTSFEKKVKNIFDKQPLTKNSEFGISIIDKDKNIILDQYG
                     FKSKEKANYEDVNNALKDIKTKNLTPYTYRIPDTGEHVMSISLPLKVNNIIEGVVRYT
                     VSLDAIDNAILKQATWLILAGIFILIIAILISLKFAETLIKPLRELKKFANELAVGNY
                     NIKLEKMKIVDDEIGDLAQTFEHMAHEIDKSEKLKEEFISSVSHELRTPLTSIKGWSE
                     TLGYESITREELDLGLGIIQDETERLIKLVEELLDFSRLSSDRIKLHVDIVDVEGLIV
                     GVVNQLKVKVAEKDISLLFEFENEFIENIQGDKNRLRQVLINLIQNSFKFTSQGGYIK
                     VVASQDEEITTISVEDNGSGIEKQNLNKVLDKFFQEDYNKAGSGLGLAISNEIVKLHG
                     GRMKIESEKNVGTKITFNIKNKFAKQA"
     gene            12131..12868
                     /gene="truA"
                     /locus_tag="KR231_001682"
     CDS             12131..12868
                     /gene="truA"
                     /locus_tag="KR231_001682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011010156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(38-40) synthase TruA"
                     /protein_id="HBH0004062.1"
                     /translation="MRNIKMIVAYDGSRYKGYQKLGDNNMTIQEKLENVLSKMTNETV
                     EIIGSGRTDMGAHARGQVVNFRTNCMDSLDKIQKYLYEYLPEDIVVKTVEEVDERFHS
                     RYNVKSKTYMYKIDNNKYHNPFIRKYATHVSKKLDLDRMRKASEYLVGEHDFTSFASS
                     KSKKKSNVREIYSINIKEDDNVIEIYVEGNGFLYNMVRIIVGALIDVGLKRRAPQDIK
                     YMLESKDRCQSSDTAPAKGLCLWKVTY"
     misc_binding    12979..13186
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            13439..14638
                     /locus_tag="KR231_001683"
     CDS             13439..14638
                     /locus_tag="KR231_001683"
                     /EC_number="6.3.4.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="argininosuccinate synthase"
                     /protein_id="HBH0004063.1"
                     /translation="MKEKVVLAYSGGLDTSIIIPWLKENYEDIDVIAVCGNVGQEDKM
                     EDVYEKALQSGASKAYVDDISEEFVTETIFKAVKAEAKYEGKYLLGTSLARPIIAKKL
                     VEVAHKEGAKYICHGCTGKGNDQVRFEATIAALDPTIKVIAPWRIWDIKSREDAIDYA
                     EKHNIKVTATKAKIYSVDANLWHVSTEGGDIEHLENEHKKDVYKQCVDPEDACDVAEY
                     VEVYFEKGVPKKVNGEELSPVALIHKLNELGCKHGIGVIDIVENRLVGMKSRGIYETP
                     GGTILYEAHNILESATLDKDTLHFKQMVSYKYGELIYNGLWYCKLRESIDAFMEQTQD
                     NVTGTVKVKLYKGNIKPAGIFTENALYDEGISSFGNSELYDHKDAEGFINLFTLPLKI
                     RAMKAGK"
     gene            14885..15931
                     /locus_tag="KR231_001684"
     CDS             14885..15931
                     /locus_tag="KR231_001684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4872 domain-containing protein"
                     /protein_id="HBH0004064.1"
                     /translation="MRKIIEIKHHSHDYECMWNGIEDLYINKTGEYLPNDFFFLLSGF
                     GSFCYMKTNKADLKRMVALGDGRTKQMYKFLAPIVGFEYKHHEFKKYEQALKKAKSEI
                     DDGYPVILGALDMYYLPYYKKLYHKEHIPFHYILMVGYDDEGIYLYDCGRTELLHLSY
                     DKLRESMNCNSPGLSKENTICTIRMNTSKNKYNIAREAIAIKRDMFLNPPKGFLGYKG
                     FEKFIKELPQWNTELDKDDYDKILTNMVMFFGTVPTIPNAIKGIKEPDTVQFKGGFDK
                     MSRMLNSIGEEYKNNSFIQVADIFDKTAIIIEKISNIIIDYLTQTCDDTEQLPLLFSE
                     VLEHMKTGYLILDV"
     gene            16039..17202
                     /locus_tag="KR231_001685"
     CDS             16039..17202
                     /locus_tag="KR231_001685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HBH0004065.1"
                     /translation="MRTVKQVSDLTGISVRALHYYDEIGLLKPNKITDAGYRLYDDES
                     IKTLQQILFFKEIDIPLREVKEIMSSQYFDKVEALKNQKKLLILKRKRLDELIELINQ
                     TLRGEGNIDFKEFDMSEYFNVLEEFKREHRNKVIKIYGSVEKYNEYIERVKSNEEKIA
                     KMAIKQYGTIEKFAKAIKTNFSSDILNLGEKFDRYKNDCLKEKHPKLKELYRKLVEDL
                     SRNPSSTDLQEIAKAITDISKKDYEIFSMDTGDDNWYYMVQNYLVNPMWIEEVDKKYG
                     SGAGKFIGQVLKTYLRDRKPKINTLYEKLVEDLSRDCSSREVQSIVEEIDNEMKRSNE
                     FYKIDNGERYFDYMSELYLQDSNYIKVTDKNYGDGASKFIGEAFKIYFDNNNC"
     gene            complement(17291..17671)
                     /locus_tag="KR231_001686"
     CDS             complement(17291..17671)
                     /locus_tag="KR231_001686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439516.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4363 family protein"
                     /protein_id="HBH0004066.1"
                     /translation="MKSTTFVILWTILFVLFGFYVNNKLYDFTEGYKDNISVLEKSIE
                     NEDWEKAQKEADSISTSWNKEKNHWYKVLNHEYFDEIGLRFNILDKAIYTENKLKSLE
                     EVESIKTYLGNIIESVKFDVNYIF"
     gene            complement(17674..18333)
                     /locus_tag="KR231_001687"
     CDS             complement(17674..18333)
                     /locus_tag="KR231_001687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF421 domain-containing protein"
                     /protein_id="HBH0004067.1"
                     /translation="MTVVLIRSIILYITVLIALRVMGKGEIAEMNCFDLVITLLIAEV
                     ASVPMENNNIPIINGVAAISGLVIMQTLISFLSLKSRKLSSFLSGKPSVLIDKGKIVY
                     KELKKERISIDELLEQLRIQGYFNLKDVQYAILETDGNLSVVPASSYNSTPPRAFNHL
                     PIPLILDGRIINKNLDIAQKDTNWLMGILKSNHIETFKDVLICVLDENDKIFIQNKKG
                     D"
     gene            complement(18439..19413)
                     /locus_tag="KR231_001688"
     CDS             complement(18439..19413)
                     /locus_tag="KR231_001688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exonuclease domain-containing protein"
                     /protein_id="HBH0004068.1"
                     /translation="MKYKLFIDFEFNILDDNKNKPKEYNGAELISIGGVLVDNEFNTI
                     DNYYSLVKPKYNKILSNKCKNLTKLNQLDINNAPNLLYVMDDFYKWFCKFDDVTIYNW
                     GDFDITGLLTSFRVYKYTGKCLELFNMMIDIQPFISQHITYNNRILSKQISLLNMKKI
                     FSVEGDIKHNSLSDAVDLMNVCKCFFFNSPKNIDILEELYNKLPALKTPLYYIPYFED
                     ENFELKFDRTPEDIIIYLKQILTILNISKKEIYFKKRSVLVNNSKIINFKNLSSSFKL
                     IKLNEFEEYPDFILKLGDKKSFVESVIKINKSNRKSIKNLILKLSKKP"
     gene            complement(19453..19800)
                     /locus_tag="KR231_001689"
     CDS             complement(19453..19800)
                     /locus_tag="KR231_001689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0004069.1"
                     /translation="MLNLKEIREEIIKKYIGDSLISELTEELKNILITDLQSNPFKSN
                     IELSIIPANIEIFKKIENILIDSKVNLKMGWERILINYILKDLFELNYEINKSCNEPL
                     MFRVIISIDSYDA"
     gene            complement(20018..20974)
                     /locus_tag="KR231_001690"
     CDS             complement(20018..20974)
                     /locus_tag="KR231_001690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902770.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-threonine 3-dehydrogenase"
                     /protein_id="HBH0004070.1"
                     /translation="MKKILITGALGQIGSELTIKLRNEYGEQNVIASSRRVKEGNPVC
                     ESGIFEILDVTDKNRFFEIAKKYDVDTIIHLASLLSAVAESKPLEAWNLNMNGLINGL
                     EIAKELDCKFFTPSSIAAFGENSPKNMTPQDTLQRPNTMYGVTKVSGELLCDYYHSKF
                     GVDTRGVRFPGLISYVTPPGGGTTDYAVDIYYEALKNKRYKSYIAEGTKMDMMYMPDA
                     LQSIVDLIEAPADKLIHRNAFNITAMSFSPEEIADSIKKYIPDFVIEYDVDPVRQSIA
                     DSWPNSLDSSSAVKEWNFKFSYDLDKMTKDMLEKLSEKGIGK"
     gene            21417..21785
                     /locus_tag="KR231_001691"
     CDS             21417..21785
                     /locus_tag="KR231_001691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C-GCAxxG-C-C family protein"
                     /protein_id="HBH0004071.1"
                     /translation="MTRPSIYHSQGYTCAEALIKSYNEEHNTDIPISIGSGMGVGMNV
                     GSVCGAVNAAVVIIGYLNGRNSNLDENIARKYSRELLNRVRNKYSSEICVSLKKNKVT
                     CEEIINFTYDALNDMLKNQK"
     gene            22210..22455
                     /locus_tag="KR231_001692"
     CDS             22210..22455
                     /locus_tag="KR231_001692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0004072.1"
                     /translation="MFIDEELEGYILTCKISEDFKNIPEYSDEEFYVTVYKDESSDSG
                     YYALLENKEERVVWDGEVVANNIFNNLWIVINKVKTG"
     gene            22554..22817
                     /locus_tag="KR231_001693"
     CDS             22554..22817
                     /locus_tag="KR231_001693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1883 domain-containing protein"
                     /protein_id="HBH0004073.1"
                     /translation="MEYSYSKMNLKKGDIVEVNLEKQANVILLDHINYVKFKNQRNYD
                     YYGGFAKKNPCRMRVPNTGTWYLVVNQDGNSGIVNFSINTIQN"
     gene            complement(23102..24049)
                     /locus_tag="KR231_001694"
     CDS             complement(23102..24049)
                     /locus_tag="KR231_001694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013378669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="(4Fe-4S)-binding protein"
                     /protein_id="HBH0004074.1"
                     /translation="MSNVTAEQKKEVKGRGFLPSRDGEHFAARIITVNGVINASQAKK
                     IAEAAEKFGNGQLAFTTRLTVELPGVKFEDIEALSEFIASENLITGGTGSRVRPVVAC
                     KGTVCVHGLADTQALAAEIHEEFYKNWYDVKLPHKFKIGVGGCPNNCIKPDLNDLGIV
                     GQRVPDYDSELCVGCKKCAVVEVCPVKAAKLTDKGKLEIDSNLCNNCGKCIESCNFDS
                     IEEKESGYKVYIGGKWGKSVRPGTQIDRLFSKEELMTLIEKAILLFREQGNTGERFGI
                     TIDRIGADKFIEMLLSDEVLERKEEILEALLHLTGGAVC"
     gene            complement(24052..25683)
                     /locus_tag="KR231_001695"
     CDS             complement(24052..25683)
                     /locus_tag="KR231_001695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HBH0004075.1"
                     /translation="MKVLIIGGVAAGTKTAAKIKREMGDNCSVTILNKGDDISYAGCG
                     LPYYVGKIIEDKSSLIVNTPESFSKLTGAEVRCGVEVTSIDRNAKQVTLKTLSTGEKE
                     NLSYDKLVIATGADPIKPPIPGIDLPGVFFVRTPNDAIKLRDSIENGIKRAVVIGGGF
                     IGLEIAENLSAMGIRVSVVDMAEHVMPGFDTDFAEYVENHMADKGIMIFTGDQVVGIE
                     GENKVEKLRTKNRAIKTDLVVMSVGIRPNTGFLKDTGLEFAPNNTIIADEYMLTNDKD
                     IYVVGDCAFVKNSLTNKPTWSPMGSSANHEGRICAQNISGKSKTYNGVLGTTVVKLPE
                     LNAGKTGLSKEIAEKEGYNVCSVTIATDDKAHYYPGASNFIIRMVAEKNTRKLLGVQV
                     MGPGAVDKIVDIAATAITLGADLYSLESMDLAYAPPFSTAIHPFVVAVNVLQNKLNGE
                     LDSVLLDEIEDFDSWTKLDVSKAPSIPSLRYIPVGEINGEIEGLAKDEKILLICAKGK
                     NSYMAQNRLRRFGYTNTKVLEGGILFYPNLKVMEE"
     gene            25813..26730
                     /locus_tag="KR231_001696"
     CDS             25813..26730
                     /locus_tag="KR231_001696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HBH0004076.1"
                     /translation="MTIRSLEIFVKVAECGKMSEVARNMYITQSSVSQAISEIEKEYG
                     VKLFDRISKKLYLTEAGKKLLGYGRHLLAVNEEMNDCMKHCAKNIRIRVGATVTVGTC
                     VISPIMLELYKVNPLIEPEVFVEDTRLIAKKLLNSELDIAIVEGKIKHPDIVTKSIIN
                     DNLVLICSHKHEFYKRDSIKVSELSNQPLIMRELGSGTRAQLEKQLKELKIPMNIRWS
                     CYNSEAILRAVVDNFGIAVISELLIEDYLKKHLLWACDIEGINLHRTFDIAYHRSKFF
                     TENISAFFDISVEYGKKQARKKSRSVNSL"
     gene            complement(26787..27368)
                     /locus_tag="KR231_001697"
     CDS             complement(26787..27368)
                     /locus_tag="KR231_001697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TerD family protein"
                     /protein_id="HBH0004077.1"
                     /translation="MGITLAKGQKVSLTKSNPGLKKVIVGLGWDINKYDGGFDFDLDA
                     SAFLTGTDGKVTNDGDFIFYNNLKHASGAVEYMGDNRTGVGDGDDEQINVDLSKIPQN
                     IAKISFSVTINEAITRRQNFGQVENSYIRIYNEETNEELIKYELGEDFSIETAIVVAE
                     LYRHNGEWKFNALGSGFEDGLAGLCKNFGVNIG"
     gene            complement(27408..27974)
                     /locus_tag="KR231_001698"
     CDS             complement(27408..27974)
                     /locus_tag="KR231_001698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TerD family protein"
                     /protein_id="HBH0004078.1"
                     /translation="MSVSLQKGQRVSLVKDNNPVKNLVVGLGWDMNKLGKKNYDLDAF
                     AIALTNQDKMNVRGDLVYFGNLKHPSKAIIHTGDNLTGKGEGDDEQIIVNLEDIPEYV
                     HKIVFGVSIYKAKKRDQDFGQMNNSFIRLIDSNSKQELFKYNLQEDFSGKVTVLAGEI
                     YRRNEEWKFNALGIGQNEELRELINTYK"
     gene            complement(28430..29290)
                     /locus_tag="KR231_001699"
     CDS             complement(28430..29290)
                     /locus_tag="KR231_001699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HBH0004079.1"
                     /translation="MLLKKDRITFSEILILIVGCILMAISLNLFFNPHAIAAGGITGL
                     GVVLNSLFGVELWIVNLLLNVPLFIFAYKILSKKDCFKTVLGIIFLTIALKLTANMAT
                     LDITNDMYLAIISGSILMGVGQGLIFRINGSTGGTDLMALLLNKYFPTFSIPVLMGIV
                     DCVVVVLSGIVNRQVEIALYSTVALYILVKVSDLLIEGFNYSKSFTIISDLSKDISKK
                     IMEDLDRGATILKGEGAYTGENKNVLLVVVEKKEVVELKKLVKNVDPNAFIIITDIHE
                     ALGNGFKKIE"
     gene            29439..30329
                     /locus_tag="KR231_001700"
     CDS             29439..30329
                     /locus_tag="KR231_001700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HBH0004080.1"
                     /translation="MAKLTLEHIKGNTYYIPLPTIVGVYVDGKDAILIDSGNNKDTAR
                     QVLRLLEEHNLNPKLIINTHSNADHIGGNAYLKNQTKCKIATTKIEGYFTENPILESA
                     FLYGGYPSKALKNKFLLAKESEVDYIIPSNGKIVDTELEAISLPGHYFEMIGVRTPDN
                     VLFVADSLTPENIITKYHFFFLLDIDSQFKTLEKLRMLEADFFVPSHSVKTTDIKSLI
                     NINKKKMEEIIDNIKKVCYEPVMIDEVIEKMCDLYNVKLDANQYVLVGSTIRSYITYL
                     YENNMVEYIFDGGKMMIKAA"
     gene            30547..32301
                     /locus_tag="KR231_001701"
     CDS             30547..32301
                     /locus_tag="KR231_001701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp23"
                     /protein_id="HBH0004081.1"
                     /translation="MYIMNKKFKKFSKKLSILILVLTMFLFNNLTANAQIKEDSIIGI
                     DRYETAGLIADRQTYDTVILVNGDKNLSDGLSSSGLAGAINAPILLTKKSEIPKATLN
                     RLDNKSLNVVKKVYIIGGYNTIENSVEKDIKRKGIQVERINGNNRIETSYNVAKKINE
                     VSSVKEVMLTNGFVGEADAMSIAPVVAKNKGAIILTDGKSVPFKTEGLNVYAIGGKSA
                     INEDLVNETKAIRIGGNDRFETNKKVMEKFYNGATDFYITNGYQLVDALTLSPLAKEK
                     PIVLVADGSNKGILKGAKSITKVGGIDANIYKQCLDMIKYNNMDMTPNILKHLTSVEG
                     NEVSEILIESDNLGVVVEKTNTNKFEFDYVSVTNEKNCTFSVYKENSSNNIKNGKLVV
                     SAKKKIDKKDSDLQDMNGDNMINANKDRMVNVIKIGVPDKMYSNFKVDVESGSVELYN
                     IKGGATVDVNDGIANIVDNNVTNPFNINTNSGISGVTAETISSEIKFRANNGIVNVTA
                     TNINGNISLFGSDNKDTFDGIFKLNLKKEPSNLHLKLIGNGINKLPEGWSKDYILGNG
                     QPIIEVKNNGINNISIGE"
     gene            32685..33671
                     /locus_tag="KR231_001702"
     CDS             32685..33671
                     /locus_tag="KR231_001702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HBH0004082.1"
                     /translation="MKKITINDIANLAGVSKSTVSRYLNNKDISDSTKEKIKTIIDEY
                     GYEPNAFAQSLRAKKTYFIGIITPCLDSFVKSKIMMAIDEELKKLKYTSLIINTNRKI
                     RSEIDSISKLASLKVDGIILIGTEITKEHKNEIEKLDIPIVVVGQKVDGINSIVNDDY
                     GAGYKMGQYIANKGYKNIVYLGVDESDISVGLNRKNGVLNGLKDKGYDAKVFYTDFDQ
                     EMSIQRSGEMLESENPDIIICATDNIAIATMKEINKRGKSIPQDISVAGFGGYDVLSI
                     ISPKLTTIKFENKNAGKVAANTIVNLIQERKEPLLKEIKFELIEGESTINKN"
     gene            33840..33988
                     /locus_tag="KR231_001703"
                     /pseudo
     CDS             33840..33988
                     /locus_tag="KR231_001703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423822.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIB"
     gene            34007..35488
                     /locus_tag="KR231_001704"
     CDS             34007..35488
                     /locus_tag="KR231_001704"
                     /EC_number="3.2.1.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sucrose-6-phosphate hydrolase"
                     /protein_id="HBH0004083.1"
                     /translation="MYKEPKYRTILESTKEELNKLRNISLNDKYKPLFHIHPQHGLLN
                     DPNGLAYYNGKYHVFYQWYPYDATHGMKHWAYVSSDDFVNWNREDVALIPIESYESHG
                     AYSGNAIEVDGKLHMYYTGNIKYSAEDRYAYQNLAIMNKDGKITKYENNPIVSEIPKG
                     YTGHVRDPKVFKRKDKYFMLLGAQTSDKKGVIIVYESKNSIDWNFKGELNVKNIDEDF
                     GYMWECPDYINIDEKDILIFSPQGVEPKGFDYQNIYNVVYAIGNMDLDNLTFEIDTMK
                     ELEKGFDFYAPQTFIKDSQIILFAWAGMGEVLYPTDKNKWAHCLTVPRKLNIKNNKLL
                     QMPVDELIKLRYDETSGQNTIKNNINIIENDENVYELNINIKNIDSNKFGLELFSSQD
                     EGVKLEFNKLGNIVTLDRSNFKKVFGVEYGTNRKEYINIDENTNIKVLADRSILEIFI
                     NEGEVVFTSRIFAKENSNQIRVYSDKIVEYEYTKFKLKQGIEL"
     gene            35514..36485
                     /locus_tag="KR231_001705"
     CDS             35514..36485
                     /locus_tag="KR231_001705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate kinase"
                     /protein_id="HBH0004084.1"
                     /translation="MKKVISIGEALIDFIPNQNGGKLKNVSEFRRVAGGAPANVSAVV
                     AKLGGKSSFISKLGKDAFGDYIIDVLNEVNVNTDYVLRTSKANTGLAFVSLKEDGNRD
                     FSFYRNPSADMLLEADEVKKEWFNNCHILHFCSVDLIDSPMKLAHKKAIEYALESNSI
                     ISFDPNIRLPLWDSEQSCKKAISEFLPFAHIVKISDEELEFITGENDIEKSLHKLFVG
                     NVELVLYTKGKDGVDAYTKKVKGMCKGVKVNAIDTTGAGDSYIGSFLYTLLYKQITLN
                     DIKEMKQETLNEYLEFSNYYAARSTTIKGAISSYATKEEITEFIKNL"
     gene            complement(36741..37343)
                     /locus_tag="KR231_001706"
     CDS             complement(36741..37343)
                     /locus_tag="KR231_001706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin family protein"
                     /protein_id="HBH0004085.1"
                     /translation="MEVCILMGSPKKKGNTAAILKPFIEELENYNSNIEVIWLYDCKI
                     EPCIACKKCQDNLFDFGCYCKDDVQKIFKKILMCDLIVFATPIYSWYCTSPMKALLDR
                     LVYGMNKYYGNEKGPALWAGKSVALITTCGYRPEKGADIWENGMKRYCKHSQLKYIGM
                     LVERDLGKPNFMNKEKEEHSRQFAKQIYYILSNSIELDNC"
     gene            37624..38835
                     /locus_tag="KR231_001707"
     CDS             37624..38835
                     /locus_tag="KR231_001707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal-dependent decarboxylase"
                     /protein_id="HBH0004086.1"
                     /translation="MYSNEDYKFIEENAPCYIYDETNIIEKCKELKNNILGFDFLYSI
                     KTNPYNKIVKSIAEQGFGADASSTNEVMISSKCGVSKDDIYYSSPGKTEIDIETVLDK
                     CIIIADSITEIELINKISKKHNQKVKIGIRINPDFTMDDDSAKSSKFGIDIEDMSSVF
                     KMLSMCDYVSVVGIHIHIKSQVLDFEKLGHYYEKCFFIALNLNKSKYINIEFINFGSG
                     LGVAYDNLRENPLNLKELSKLTQKIAFTNSNTLKSRLLIESGRFIVCKSGNYYVKIVD
                     IKVSRGKKYLIVKNGLNGFMRPIISNLIENITCGVELEGQEPLYTSNHAFSLSVLNNL
                     KEEEYVNVVGNLCTSLDVIANNVKLKKANIGDLISISNAGSYSYSLSPLLFSSYEFPK
                     QYYKRKDGYIE"
     gene            38903..39100
                     /locus_tag="KR231_001708"
     CDS             38903..39100
                     /locus_tag="KR231_001708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug transporter"
                     /protein_id="HBH0004087.1"
                     /translation="MELWKRNLFVCWIGMFFSSIGMSQIAPILPLYIKQLGVTDVSLI
                     QQYSGIIFGCTFVVAAFFSPI"
     gene            39134..40105
                     /locus_tag="KR231_001709"
     CDS             39134..40105
                     /locus_tag="KR231_001709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBH0004088.1"
                     /translation="MLLRASIGMGIVIFTMAFVQNVYQLLGLRILQGVFTGYATACTT
                     LIATQTDKNHSGWALGTLATASTTGSLIGPTVGGYIESILGLKSTFIITGGLLFVSFI
                     ISILFVVDNFKPKEIKESISIPKEQLNILPNKFLIASIFVTTFITQLALYSIEPIVTI
                     YISQLTNFASNVALIAGLTFSASGLANLLAAQKLGKMSDKIGPQKVLLISLLWAGIIF
                     IPQAFVKTAWQLMLLRFLLGLSVAGLNPSVNSLLKKIAPEEYVGKIFGYNASAQYIGC
                     SSGAFLGGQISAHLGIRTVFFSTSLLLFRNALWMYKFTGLFIKDKTK"
     gene            40292..40669
                     /locus_tag="KR231_001710"
     CDS             40292..40669
                     /locus_tag="KR231_001710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
                     /protein_id="HBH0004089.1"
                     /translation="MTISKIPQAELKVMKFIWEKNDTVTSKETIEAMERKYGWKQTTT
                     LTLLSRLVKKHFLSAEKIDRYTHYTIVVGHKEYLSVETKDFLSNIHDNSLQSLISALH
                     DDEVVDKDMLDLFESHFKNLEEE"
     gene            41200..>41798
                     /locus_tag="KR231_001711"
     CDS             41200..>41798
                     /locus_tag="KR231_001711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine kinase"
                     /protein_id="HBH0004090.1"
                     /translation="MLDAFITIVSSIIEIWSCKKVFDYTSQSKTDLKKLNMYFLFSVF
                     LIISSLYINIGANSRILICIFVMFVFYKSNYKVNIYKCLVISFFYWLILIGINGLSML
                     LVATVSNLDNMNVLLSGSLYRYEAIFLGKIMLGILLYVYKASFKNFKISKKEIYICIP
                     MIANLLSFFVLYDYIINLVKISPERRTAFLVIVLLLILS"
BASE COUNT        16359 a         4610 c         6585 g        14244 t
ORIGIN      
        1 aaggtgtata taatagttta gatgatatga tataaaatat gttgtaaatt aaatgttttc
       61 tttgacaata tatacacaag gatgataata tctatatgaa taaaagatag tgtgtaattt
      121 gataatatgt aattataaca ttatgatata attacaataa agtatgtaat aatctgtaga
      181 aatttcaagc tagttatcta agttttcgga taactaaatc taaacggaat acataatgta
      241 ttaaataaat gatgatacta aaatgatact atttttatag aaatttattg aggtatataa
      301 ttaatgaaaa taatatatta aattatataa attaaattat ataaattaaa ttatataata
      361 tattgagttt tacataaaag caaaggtggg aataaaaatg aaagaaattg ctgatgctat
      421 aacatcagag tatttaagct atggtatcaa tgaagatatt agtatctatg aaggtagatt
      481 ttgcatatat ttagataaaa aatatagatg taatgggaaa atttattata aaatgacacc
      541 tccaatatct ataagtttta aagcagacat aggttgtgtt gaagagatag acaatgaaga
      601 tgacaattta gctttagatt atgataatgc tattcttgaa gttcatggat ataaaattat
      661 ttctataaca ataaatactt taagtgaatt tagtgtagaa ggttatatca atgatgactg
      721 cataaaatct aagaactcct atgttgaata tgtagatttt aatataataa acttagataa
      781 aatacctgga aaactcatta aatacaatga taaggtatac gcaggtagaa ttgaatttga
      841 tataaatgat tatgttgtaa ctatagacaa gcgatatgat tatagaaaag aattaaaatc
      901 agaattaaag tctaaatctg gagcaataat aactcatata ggtaggatta gaagaaaaga
      961 tggtagaatt tttagaacaa ataatacaat aaatctttta gataggatat caacagcttt
     1021 gagttttatg tgtggaagat atgtagggtt ttgtttggcc aaagggtata gaagtggtaa
     1081 tgaagtttat agaatatgga atgaaaatca aatatctcct tttagatatg taccaacatg
     1141 gtcagataca ctttcaaatt attataatat ggaaaaatat ataagcctta tgtgtaaaaa
     1201 gctagaagat ttttattatg gttctgctat aaagagtgtt gttgattggt acatagaatc
     1261 tcttggaagt gctaccatgg aaaacaatat aatatctgta caaattgcac ttgaaacttt
     1321 gtcatatgta attctagtgg aacaaaataa gatacttaca gatgaagtat ttgactgtaa
     1381 tttggcatct aaaaatataa gactcttact tgatacatgt aagataccat atggtaaaca
     1441 tgaattaaat atatttgata atataataaa aaataaattt gatgatggag tggatttagt
     1501 tatttattta agaaatagca tagttcatcc aagtagaaag actcatagag ctgtgttaga
     1561 ggttgaagat atttggaata taatttcaat aggaacgaga tatattgaac ttgttttact
     1621 ctttatttta ggttatagag gagaatattc aaacagatta gtagaaagat gttatggtga
     1681 agtggaagtt gtaccttgga actagatttt tatatttatt ttaaaatata tattgacata
     1741 tattgcctta tgctataaaa tcaatatcat aataataatt cagaataaca ttaaatgcta
     1801 agaaaagaaa tagtaaaagt agttaatctt aaacagagag tttccgattg gtgagaggag
     1861 caatagattt tactttgaac acatctttga gcaggactct gaaagagtag aaatacttta
     1921 ttaggagatt tccggaatcc ttgcacccgt tatagtgcta gagtataata attttattgt
     1981 acttaaagag gttagtgtcg tgaggcatta atgaacagag gtggaaccac gagagttaac
     2041 tcccgtcctc tagcagaagc tagaggcggg agttttttaa tataattttt taagcgcgca
     2101 gagaattata ttgcaataga tacacttttt aaaaaataat caaaatattt taaaaattaa
     2161 aaggcgaggg agaatattat gaaaaatata ttaaaaaaag taggaatatt tacaattatg
     2221 ttaggtttat taggtggagt tgtaggttgt tcaaaaccag ataatgaaaa agataaggat
     2281 gcttcaaagg aatctaaaaa agaagtagtt gtagggtttg ataatacgtt tgtaccaatg
     2341 ggatttttag atgaaaaggg agatacagta ggatttgacg tagacttagc taaagaaaca
     2401 tttaaaagac ttggaatgga agttaagttt cagcctatag attggtcaat gaaagaaact
     2461 gaattaaatg attcaaaaac tgtagatgta ttatggaatg gatattctat aacagacgaa
     2521 agaaagaaaa tagtatcata tacagaacca tatttacaaa ataagcagat aatagttact
     2581 ctaagtgact caaaaataaa ttcaaaagct gatttaaaag ataaagaagt tggaacacaa
     2641 caaggttcaa cagcacttga tgcagtggaa aaggataaag attttatgaa tagcttaaaa
     2701 ggtggagcac cagttcttta tgatacttat gataaagcac ttagagattt agagataggt
     2761 agaactagtg cagttgttgg tgatgaagtt ttaattagat actatatggg acaaaagggt
     2821 gaagacaaat acaaggtatt aaaagacgat tttggattag aagattatgt tgtagcaact
     2881 tctaaagaaa atccagaact ttgtgagaaa ataaatgaaa cattaaaaga aatgaaaaaa
     2941 gatggaactt ttgacaagat ttatgataag tggtttaaat agaagataag ttagctgtta
     3001 agaagggggc actaaaggca tgttacaagg tttagagata gttatagcaa tgttttgtat
     3061 aacattgata gtatcaattc cattggggat tggagttgca tttttaagat tatcaaagaa
     3121 taaattagta agtggtatta cacaatgtta tatattgata atgagaggta cacctttact
     3181 tttgcaaatg atagtcatat tttacggatt acctctttta ggaattgtat ttgacagatt
     3241 tacagctgga gtagtagctt tcttcttaaa ttatgcagca tattttgcag aaatatttag
     3301 aggtggaata cagtcaatcg atagaggaca atatgaagct tcaaaagtac taggatttga
     3361 taagtttact atgtataaga gagtaatctt tccacaagtt tttaaaagaa tactagcacc
     3421 tatttcaaat gaagtaatca cattagtaaa agatacatct ttagtatata tattaggatt
     3481 aaatgatatt ttaagaatat ctcaaatagc aatgaacagg gaagcaagtc tgttaccatt
     3541 atttgaggca ggagcgatat atcttatatt tgtagctata cttactaagg gatttgaatt
     3601 acttgaaaaa aaatattctt attatagata aagttacaat attataggag gaggtttttt
     3661 atatgttgaa aatcaaaaac ttaaataaat catttaaaaa aaatagagta cttaaagata
     3721 tttcttttga gttagaagaa ggtcagattg gagttttact tggtaagtct ggtgcaggaa
     3781 agaccacaat attaaggtgt ataaatggtc ttgaagaatt tgatagtgga gagattataa
     3841 tagataatga ggtaataaaa aataagagag atatggcaaa aatacgagga aaaataggta
     3901 tggtttttca aaatttcaac ttatttcctc atatgacagt ccttgaaaat ataattgaat
     3961 ccccagttaa tgtttttaaa gttcctagaa aagaggctga agagagggct agagaacttt
     4021 taagattagt tgatttagaa gataaattaa attcttatcc atttgaattg tcaggaggac
     4081 agcaacagag agttgctata gctaggtcat gtgcattgat gccaaaagtc ctttgttttg
     4141 atgaacctac ttctgcactt gatattgata ctattcaaag agtagtcaat ataatgaaca
     4201 gacttaaaga caaaggtatg acaatattaa taattacaca tgatgttgtc ttctcaaata
     4261 atgttgcaga taaaattata agtataaaag atggtatagt agaaaatgtt caaataaaag
     4321 aaaaaattgt ttagagtttt ataaatataa actagggtag aattttataa tataaataaa
     4381 gggcaagtaa aatcaaatat actatgccct tttgttatct caaaatttaa tcttatattt
     4441 tatgtttaag ttacattata atttataata aaaataaaag gactatttaa atatataatg
     4501 tgaataatgt ttaataattt gaaatatgat aattttttat gttgaaagct tataatgatt
     4561 atgatataaa ttggttatag tatacaattt atgggtataa caataaaaaa ttagaaagga
     4621 atttttataa aatgattaaa ttatatggat atacaaaatg ctctactgtt aaaaaagcta
     4681 aaaattggct taaggaaaat aatttagaat ttgaagatat agatatggtt caaaaccctc
     4741 ctagtaaaga ggagttaaaa tcaatttata agactagtgg atatgatata aagaaatttt
     4801 ttaatacaag tggtatgaaa tatagagaat tgggtcttaa agatattgta aaaactgaat
     4861 ctgatgataa acttttagaa atattggtaa gtgatggtat gcttattaaa agaccattac
     4921 ttttggatgg taaaaatgta ttattgggtt ttaaagaaga tgtatggaaa agtactttgc
     4981 taaaagaaga ttaggaagag ataggtgtgt tgattaaaat tattaattaa tacacctata
     5041 aatttatgta ttaaatctaa tctttataaa tattaattag caaattcaaa tcaaaaaaat
     5101 tcatatcaac aaacatatta cttcttatta caaattatat catatgtttt atattaaaat
     5161 attataatat tacaacgaat tgttacaaaa ttacttatta ttaaccatga acatttgttt
     5221 tgtgctatca tatttatata agggaattgt cataaaaaat atcttgttca tacagtttta
     5281 tatagaaaaa agaaatgaat cttttcttta tataagtata ttttgtaaat tgcctctata
     5341 tttatagttt aaataatagt ggtattaaaa atctgacaac aaaaataaaa ctttcaaaaa
     5401 attaaatcta aaaagaatag gagataaata tgagtattga agatttatat gattttgaat
     5461 gtgttccttt gaacaatgag attgatattg atgttttatt tgaaaagatg atagaagatg
     5521 gaaaagaaaa agaatataca ccaattatag tcattgatga aaaagtaggg ctattaagaa
     5581 aaaatataga tatgattact aaagagtatg gttctcttga aaactataga gagtattgtt
     5641 taacaaaata taatgaaatt gatgtaaatc aattttttga ttttaggaag agtgagattt
     5701 cagaattatt aaaggagcta attgatttag aagatgattt ttatgattat aaacatttta
     5761 gacccattat gaatatagat atatttcatg aatataacaa agtttacata gctaaaattc
     5821 caacaattaa accatatgaa gtatttgcat acatacctat tggcggattt aatgattgtc
     5881 ctagagatga agaacatata gctattgcaa aatattggta tgaaaagcat ggaatctttc
     5941 caatcgcaat tggatgtgat acagttcaat attctgtaaa aaatttaact aaagatggta
     6001 aaaaatttga tgacttatgt attgaattag tattttattg tgaggatatt attatacaag
     6061 ggtatgaaac cttaaaggct cttaaggatg tattaaaacg ctctacaata gtgctttttt
     6121 ggtgggattg atattctatc atttagatag tattaaattg ttagtcacca agaatccact
     6181 tgctttagtt atagggagtg tgtcaaacta ggtttttata cacagtgtag catagtaata
     6241 tgtttaaatt acaaaggtta aaaaaatact ttaatatttt taatattata attaatagat
     6301 ttaaggtaat tataatttat aaaataaata ctttatatgt tataatcatt aagaatgtaa
     6361 aaaaataata tatagtttta tagttcatat ttttccagat atggaggtaa attttgtgaa
     6421 ggaaaaagaa aaattagata aattaaaaaa aatgttactt gaattaggca gtgttgtagt
     6481 tgcttattct ggtggagtag atagtaattt tttgcttaag gtcgcaaaag atacattagg
     6541 tgaaaatgtt atagctgtga ctattcatgc aatgatgcat tcaagtaggg aaattgaaga
     6601 ggctaaacaa tatactcaaa attttggtgt taaacatatc atattaaata tagaaaactt
     6661 tgatttaaaa gaatttaaag aaaatggtgt tgatagatgt tatcattgta aaaaatatat
     6721 attctctaaa ataaaagagg tagcaaaaga acataatata aagtacatag tagatggaac
     6781 aaatatagat gatttaggag actatagacc tgggcttaag gcattgagtg aattaggagt
     6841 aattagtcca ttaaaagata gtagtttaaa aaaagaagaa attaggtcgc tttcaaaaac
     6901 attaggatta aatactttta ataaaccatc atttgcatgt cttgcgagta ggatacctta
     6961 tggagttgaa ataacagatg aaaatttaag aatagtagaa aagagtgaag aatatctatc
     7021 caatttaggt ttttctcaat ttagagtgag aatgcatgga gatatagcta gaatagaagt
     7081 tggacaggaa gagctaggta aattttttga aaataacaat tttaataaag ttgatactaa
     7141 attaaaaata tttggcttta aatatgttac actagatatg tcaggatata aaatgggaag
     7201 catgaattta aatgtgtaga ttattttaaa aataaataag ttttatagtt aatataagga
     7261 aacaggaggt tttatgaaaa attatacgtt aatatcgcca tgtttttttg gaatggaaaa
     7321 aatgctggct agagagatta ctaatttagg atatgaaata ataaaaacag aagatggaag
     7381 aataacatat aaaactgatg agtttggaat agcaaagtca aacatgtggt tgagatgtgc
     7441 tgaaagagta catcttaaaa ttgctgaatt tgaggcaaaa agctttgatg aattatttga
     7501 aaatacaaaa agaataaact ggtctagata tataccttat ggagctcaat ttcctatatc
     7561 aaaagcttcc tctataaaat caaaattata cagtacacca gatgtacaag ccatagtaaa
     7621 aaaggctata gtagaaagct taaagaaaag ttatttggag gatggtttgc ttaaagaaga
     7681 taaggagaaa taccctattt ttgtatttat acacaaagat aaagtaacca tttctataga
     7741 tacaacagga gatgctttgc ataagagagg atatagagaa aaggcaaata aagctccaat
     7801 aagagagact ttagctgctg ggcttattta tttaactccc tggaaagcag gtagagtttt
     7861 agtagaccct atgtgtggtt ctggtactat attgattgaa gctgctatga ttggtataaa
     7921 tatggcacct ggcttaaata gagagtttat atcagaaaag tggagaactc ttgataagaa
     7981 aatatggtgg gatgtaagaa aagatgcttt taataagata gataatgaat ctaaatttaa
     8041 gatttatgga tatgatatag atgaagaatc tatagatata gctagagaaa atgctgaaat
     8101 agcaggtgta gatgaatata tagagtttaa tgtaggagat gcaactcaat ttaaaagtga
     8161 agatgagttt ggatttataa tcactaatcc tccttacgga gaaagattag aagataaaga
     8221 cagtgttaaa cagttgtata aggagcttgg ttatgcattt agaaaattaa aaaattggtc
     8281 gtattatttg ataacttctt atgaagactt tgaatatgag tttgggcaaa aagcagataa
     8341 aaaaagaaaa ttgtataatg gtatgttaaa aactaacttt ttccaatatc cgggtcctaa
     8401 gcctcctaga aataataaat aagttttaca tgatttattt gtaaaatata aaattttatt
     8461 aaaataagta aaacattatg atgccctgaa acgtctaatt attgtgagga gatttttgtg
     8521 aacaaattta aagatttata ggattaggag gagttaaatg aaagtgttaa agcttattac
     8581 tgtagtagcc ctgatgatgt tatttgttac tggatgtaat ataaaaactg aatctccaga
     8641 acaattagcg aagatacctg actatgatga tacaaaaaaa gtattgtatg atggtattga
     8701 ccagttacta aaaccagatt catctatgat attgccttct aatacaaaag aagtaggaaa
     8761 aataaataag gtagatttaa acagcgatgg aattgatgaa ttagtagtat ttgaacaaaa
     8821 agaagattta agtaataatg tgagtcaggt agggtttgta accttgagtt acaatggaga
     8881 aaaatacgta cttggagacc attttttaga aaatggcgaa tcaatagaat atgctaattt
     8941 ttatgatttg gactcagatg gatataagga agttatctta ttggttaaat ccaaagacaa
     9001 aacgaatatg catatatata aagtagtaga taatgaaata acaaaaatat atgacttgga
     9061 tgcatcatgg cttcaaaata aagaagattt taatgacatg aaagtaaaaa ttggatatat
     9121 agatggagat gacaagttag acatattgat gcttcatttg aataataaga ctaatgaaat
     9181 gtttgcaagt gttgcaaatt ttgatgggaa aatgaaaatc aaagattctg ttaagtttga
     9241 aaatgtaaaa aacttaagtg aattatatat aacattaggt aatgttgctt catctgttgg
     9301 aaattcttct gcagctataa aaggtattgt acttgatatt cctatattga aagataataa
     9361 ctatattacg cagatacttt atatgaaaga tgggaaaatt aacaaagctt ttagtgatta
     9421 tgataaaact attactaaat cttattatat acctgtagat gatattgaca aagataagat
     9481 tatagaaata cctatagttg caggcagtac aggtaataat aaaaatactt atagttctaa
     9541 atcatctgca actataagtt ggtatagatg gaatggaaaa gaaggtgctg actcaagttt
     9601 aatatttaca agtcagatat attataatta taaatataat tttaaattat ttattccaaa
     9661 taatttattt gataaaatac ttgttgaaca ggaatttgtt ggagaaaaag cagtatttaa
     9721 attttactat tttgactatt cagaccgtaa gaatttattt aatatagtag tagagagtaa
     9781 aaataaactt gaagatagaa aaaatacagg tactcaaaat tctattgtac ttcaagagag
     9841 cgatgaatat actttcttac tagttgtaaa caatgcaaat gaaatggata agctagatat
     9901 gactatagac gcattaaaag aatatttctc attaatatat ggttaatatt atactcaatt
     9961 ggaggtttta ttttatgaag gaaaagatac ttatactaga agatgaaatt ggtattagaa
    10021 gttttgttag tataaactta aaaagggaag gctatgaaat agttgaggca ggtactggaa
    10081 gagaagctat agaaaaaatg acaacagaaa aggatattac aatagctctt ttagatgtaa
    10141 tgcttccaga tataagtggt atagaagtat gtaaatttat aagggagaat tttgaccaag
    10201 taggtataat aatgcttact gctaaagctc aagaagatga taaaatagaa ggatttatct
    10261 caggagcaga tgattacatc ataaaaccat ttagtataaa agagctttta gtcagagttt
    10321 ctgctcttct tagaagagta gcaaaggatg attcaagtgt taagtcgagt gagatagttt
    10381 ctccaccatt tatacttgat atagacaaaa gaaaattatt taaaaatgga aaggaaattg
    10441 agcttacacc aactgaattt tcaatagtga aatatctaat atcaaatgct aagcagtcgt
    10501 taagtagaga ccagatatta gacgaagtat ggggaactaa ctatttatat gattttaaaa
    10561 tagtagatgt aaatataaga aggataagaa ataaaataga agatgaccca tcaaaaccaa
    10621 aatatataca aactatttgg ggttatggat actgttttag aaaggaagaa taatagtgtt
    10681 acattttgaa ggtctgagaa aaaaagtaat aaaaaactat tttataataa ttattataat
    10741 ggttactctg tttgaaggat tgttcatgtt ttacatacaa aactactatt atgattctgt
    10801 caaacagcta cttgaatctg aaataaaata tgctgatgaa tataatgcta ttacaatgga
    10861 aactacaagt tttgagaaaa aagtaaaaaa tatatttgat aaacaaccct taactaaaaa
    10921 ttcagaattt ggaatttcaa taatagataa agataaaaat attatattag accaatatgg
    10981 ttttaaaagt aaagaaaaag caaactatga agatgttaac aatgcattaa aagatataaa
    11041 aactaaaaat ttaacacctt atacttatag aataccagat acaggggagc atgttatgag
    11101 tatctcctta ccacttaagg taaataatat aatagaaggt gttgttagat atacagtatc
    11161 attagatgct attgataatg caatattaaa gcaagctaca tggcttatat tagcaggaat
    11221 atttatactt attatagcta tactaataag tcttaaattt gctgagactc ttataaaacc
    11281 attacgagag ctaaagaaat ttgcaaatga attggctgta ggaaattata atataaaatt
    11341 agaaaagatg aagattgtag atgatgaaat tggtgattta gcacagacat ttgaacacat
    11401 ggcacatgag attgacaaaa gtgaaaaatt aaaagaggaa tttatatcat ctgtatctca
    11461 tgaactaagg actcctctta catctataaa ggggtggagt gaaaccttag gttatgaaag
    11521 tataacaaga gaagaactag acttaggttt aggcattata caagatgaaa cagaaagact
    11581 tataaaacta gttgaagaat tattagactt ttcaaggctt tcttcagaca ggataaaact
    11641 tcatgttgat atagttgatg ttgaaggttt aattgtaggt gttgtaaatc aacttaaagt
    11701 taaagtagct gaaaaagata tatcactttt atttgaattt gaaaatgaat ttatagagaa
    11761 cattcaagga gataaaaata gattaagaca ggttctcata aatttaatac aaaattcatt
    11821 taaatttacg agtcaaggtg gttacataaa agttgtagct tctcaagatg aagagataac
    11881 aaccatatca gtagaggata atggttcagg tatagaaaag caaaatttaa ataaagtgtt
    11941 agataaattt ttccaagaag attataataa ggctggtagt ggattaggac tagcaattag
    12001 taatgaaatt gtaaaacttc atggtggaag aatgaaaata gaaagtgaaa agaatgttgg
    12061 aacaaaaata acttttaata taaaaaataa atttgctaaa caagcataaa ttcttagaaa
    12121 gaggattaag atgagaaaca taaaaatgat agtagcatac gatggttcaa gatataaagg
    12181 atatcaaaaa ttaggtgaca ataatatgac tattcaagaa aaacttgaaa atgttttaag
    12241 taaaatgact aatgaaacag tggagataat aggttctgga agaactgata tgggagctca
    12301 tgcaagagga caagtggtaa attttagaac taattgtatg gattctttgg ataaaattca
    12361 aaaatattta tatgaatatt taccagaaga tatagttgta aaaactgttg aagaagttga
    12421 tgaaagattt cattcaagat acaatgtaaa atcaaagact tatatgtata aaattgacaa
    12481 taataagtat cataatcctt ttataagaaa atatgctact catgtaagta aaaaattaga
    12541 tttagataga atgagaaaag caagtgagta tttagtagga gaacatgatt ttactagttt
    12601 tgcttcttct aaatctaaga aaaaatcaaa tgtaagagaa atttattcta taaatataaa
    12661 agaagatgat aatgttatag aaatatatgt agaaggaaat ggatttttgt ataacatggt
    12721 aaggataata gtaggtgctt tgatagatgt tggtctaaaa agaagagctc cacaagatat
    12781 taagtatatg cttgaatcaa aagatagatg tcaatcatca gatactgcac cagctaaagg
    12841 actatgtctt tggaaagtaa catattaatc aattatataa aactctcttt aaaataaaaa
    12901 taaaataaat tatatagttg acataaatgg aaaaataaac tattatatat tttataagag
    12961 agatataaaa ctttatattt aaatcctgtg agaaagagag taacttctat gtgttttata
    13021 gagagctgag gatggtggaa gcttggcaaa taagtattag tgaaaagaac tttggaggat
    13081 actaattgaa tttagtatgt tagtaggtaa tctcgcctta agagaaagag tggataagtt
    13141 tatcttatca attagagtgg taacgcggat atatttcgtc tcttggtttt tccaagaggc
    13201 gttttttaat atatttaatt attagtgttt atctggtatg ttgaacattt actaattgat
    13261 tagctaagtt tatcaataag agtggtaccg cggatatttc gcctcttagt attttaaaat
    13321 actaaggggt ttttttagta ttaaaatgat tttatgtgag tctaaattct cagagtcatt
    13381 caatattaag aatttctata aaataaaaat tataatttaa gattgggagg aattaaaaat
    13441 gaaggaaaaa gtagtattag catattcagg aggacttgac acatcaatca taataccttg
    13501 gttaaaggaa aattatgaag atatagatgt tatagctgtt tgtggaaatg taggtcagga
    13561 agataaaatg gaagatgtat atgaaaaagc tttacaaagt ggagcatcaa aggcatatgt
    13621 ggatgatata agtgaagaat ttgtaactga aactatattt aaagctgtaa aagcagaggc
    13681 taaatatgaa ggaaaatact tattaggaac ttctttagca agacctataa tagctaaaaa
    13741 attagttgaa gttgctcata aagaaggtgc aaaatatata tgccatggat gtacaggaaa
    13801 aggtaatgac caagttagat ttgaagctac aattgcagct cttgacccaa ctataaaagt
    13861 tattgcacct tggagaattt gggatataaa atcaagagaa gatgctatag actatgctga
    13921 aaaacataat ataaaggtaa cagcaactaa agctaaaata tattcagtag atgccaacct
    13981 ttggcatgtt tcaacagaag gtggagatat agagcaccta gaaaatgaac ataaaaaaga
    14041 tgtttataaa caatgtgtag acccagaaga tgcatgtgat gtagctgaat atgtagaagt
    14101 ttactttgaa aaaggtgtac ctaaaaaggt aaatggcgaa gaattatctc cagttgcact
    14161 gattcataag ttaaatgagt tgggttgtaa acatggaatt ggtgttatag atatagttga
    14221 gaatagactt gttggtatga aatcaagagg tatatatgag actccaggag gaacaatcct
    14281 ttatgaagca cataatattt tagaaagtgc tactttagac aaagatacat tacatttcaa
    14341 acaaatggta tcttataaat acggagaact tatttacaat ggactatggt attgtaaatt
    14401 aagagaatct atagatgcat ttatggaaca aactcaagat aatgttacag gaacagtaaa
    14461 agttaaactt tacaaaggaa atataaaacc tgctggaata tttactgaaa atgctcttta
    14521 tgatgaagga atatcttctt ttggaaatag tgaactttat gaccacaaag atgcagaagg
    14581 atttattaat ttattcactt taccattaaa aatcagagct atgaaagctg gaaaataata
    14641 aaataaatta tttaagagtg tataaaaacg atttttaggt ttttatatgc tcttttttta
    14701 tttgaattta ttaaattata cagtaaatag tataaaaaaa tatattatag ttccaaatgg
    14761 cttaataatg tgaaaatata agacctaaaa tataaatttt ataaatacaa tagttattga
    14821 ctctctcatt gtaagagggt ttatactgaa tctaatgaaa atttatagtg aggagataga
    14881 ttatatgaga aaaataattg aaattaaaca tcattcacat gattatgagt gtatgtggaa
    14941 tggtatagaa gatttatata taaataaaac cggtgaatac cttccaaacg attttttctt
    15001 tttactgtca ggttttggtt cattttgtta tatgaaaaca aataaagctg atttgaaaag
    15061 aatggtagct ttgggagatg gaaggacaaa acagatgtat aaatttttag caccaattgt
    15121 tggatttgaa tacaaacatc atgagtttaa aaagtatgag caagcattaa agaaagcaaa
    15181 atctgaaatt gatgatggat atccagttat tttaggagct ttagatatgt attatctacc
    15241 atattataag aagctatatc ataaagaaca tattcctttt cattatatat taatggtagg
    15301 atatgatgat gaaggaatat atctgtatga ttgtggtaga acagaattat tacatctttc
    15361 ttatgataaa ttacgtgaaa gcatgaattg caattcccct ggattaagca aagaaaatac
    15421 tatttgcaca ataagaatga atacttcaaa gaataaatat aacattgcta gagaagctat
    15481 tgctataaag cgtgatatgt ttttaaatcc acctaaagga tttttgggat ataaaggttt
    15541 tgaaaagttt attaaagagt tgccacagtg gaacactgaa ttggataagg atgattatga
    15601 taagattttg accaatatgg ttatgttttt tggaacagta ccaacaattc caaatgcaat
    15661 caaaggaatt aaagaaccag atactgttca atttaaaggt ggatttgata aaatgagtag
    15721 aatgctcaac agtattgggg aggaatacaa aaacaactct tttatacaag tagctgatat
    15781 ttttgataaa actgctatta taattgagaa aatatccaat attataatag attacttaac
    15841 tcaaacatgt gatgatacag aacaacttcc gttattgttc tctgaggtct tagagcatat
    15901 gaaaacagga tatttaatct tggatgtata aaaaatatat tgttgaccct aacattacgt
    15961 aatagtgtaa tatgaaaata tagcttaaat atattagtag gtattgatgg ctgtaaaatt
    16021 aaaatttgag gtgtggatat gagaacagtg aaacaagttt ctgatttaac tggaataagt
    16081 gtgagggcat tacattatta tgatgaaata ggtcttttaa aaccaaataa aattacagat
    16141 gcaggatata gactttatga tgatgaatct attaaaactc ttcaacaaat tttatttttt
    16201 aaggagattg atattccttt aagagaggtt aaggaaataa tgtcaagcca atattttgat
    16261 aaggttgaag ctctaaaaaa tcaaaaaaaa ttacttattt taaaacgaaa gagactggat
    16321 gaattgatag agcttataaa tcaaactcta agaggagaag gaaatattga ttttaaagag
    16381 tttgatatga gcgagtattt taatgtttta gaagaattta aaagagagca taggaataag
    16441 gtaattaaaa tttatggtag tgtagaaaaa tacaatgaat atatagaaag agttaagtct
    16501 aatgaagaga aaattgctaa aatggctata aaacaatatg gaactattga gaagtttgct
    16561 aaagctataa aaacaaattt tagcagtgat atattgaatt taggagaaaa atttgataga
    16621 tataaaaatg attgtttaaa agaaaaacat ccaaaattaa aagaattata tagaaagctt
    16681 gtagaagatt taagtaggaa tccttcttca acagaccttc aagaaatagc aaaagcgata
    16741 acagatatat ctaaaaaaga ttatgaaatt ttctctatgg atactggtga tgacaactgg
    16801 tattatatgg ttcaaaatta tctagtaaat cctatgtgga tagaagaagt agataaaaag
    16861 tatggaagtg gagcaggaaa gtttattgga caagtactaa agacttatct aagagataga
    16921 aaaccaaaga taaatacatt gtatgaaaaa cttgtagaag atttgagtag agattgttct
    16981 tcaagggaag ttcaaagcat tgttgaagaa atagacaatg aaatgaaaag aagtaatgaa
    17041 ttttataaaa tagacaatgg tgaaagatac tttgattata tgtcagagct ttatttacaa
    17101 gattctaact atataaaagt aactgataag aattatggtg atggtgcatc taagtttatt
    17161 ggagaagctt ttaagattta ttttgataat aataattgtt gaaaatttgg aagtaaaaaa
    17221 tatgtaagtt ttataaaagc acaaaaataa ggatgtagat tagctccatc tatatcctta
    17281 tttaaagtta ttaaaatata tagtttacat caaacttaac actttcaata atatttccca
    17341 aatatgtttt tatactttca acttcttcta aagattttaa tttattttca gtataaattg
    17401 ctttgtccag aatattaaac cttaatccta tttcatcaaa gtactcatga tttaaaactt
    17461 tgtaccaatg gtttttttct ttattccaac tcgtagatat tgaatcagct tctttttgag
    17521 ctttttccca atcttcattt tctatagatt tttctaaaac agatatattg tctttatatc
    17581 cttctgtaaa atcatatagt ttattgttaa cgtaaaatcc aaataataca aataagatag
    17641 tccatagtat aacaaatgtt gtagatttca atattaatca ccctttttat tttgaataaa
    17701 tattttgtca ttttcatcta aaacacaaat aagaacatct ttaaaagttt ctatgtgatt
    17761 agattttaaa atacccatta accagttagt atctttttga gctatgtcta gatttttatt
    17821 tattattcta ccatccagta taagtgggat aggtaaatga ttaaaagctc ttggaggagt
    17881 actattgtag cttgatgctg gtacaacact tagattacca tcagtctcca aaatagcata
    17941 ttgtacatct tttaggttaa agtatccttg aatcctaagt tgttctaata attcatctat
    18001 actaattctt tcttttttaa gctctttata tacaattttt cctttatcta ttaatacaga
    18061 aggtttacct gataaaaatg aacttaattt tctgcttttt aatgataaga atgaaattag
    18121 agtctgcatg attacaagtc cagatattgc tgcaacacca tttatgattg gtatattatt
    18181 attttccatt gggacagatg caacttctgc aattaatagt gttataacta aatcaaaaca
    18241 gttcatttca gctatttcac cttttcccat gactctaagt gcaattagca ctgttatgta
    18301 taatataata cttcttatta atactactgt catatctatc aattactcct ttaaaaaata
    18361 tttacactta gttagtatat cctatataaa aaatttaatt caaagtataa aaaaccttaa
    18421 ataattggat tcaactattt aaggtttttt tgataatttt aatattaaat tttttatgga
    18481 ttttctgtta cttttattta ttttaataac agattcaaca aaactctttt tatctcctaa
    18541 ttttaagata aaatcaggat attcttcaaa ttcattgagt tttattaatt tgaaagaaga
    18601 agatagattt ttaaagttaa taattttaga gttattcact aatacacttc tttttttaaa
    18661 ataaatttct tttttactta tatttagtat agttaatatt tgtttaagat atattattat
    18721 atcttctgga gttctatcaa atttgagttc aaaattttca tcttcaaagt agggaatata
    18781 atataaaggt gttttgagag caggtaattt attatataat tcttcaagaa tatcgatatt
    18841 tttaggggag ttaaagaaaa agcatttaca tacattcatt aaatccacag catctgaaag
    18901 tgagttatgt ttaatatctc cttctacaga aaaaattttt ttcatattca gtaaagatat
    18961 ttgcttagat aagattctat tattgtatgt aatatgttga gatataaaag gttgaatgtc
    19021 aatcatcata ttaaataact ctaagcattt acctgtatat ttatacactc taaatgaagt
    19081 tagaaggcca gttatatcaa aatcacccca attatatatt gtaacatcat caaatttaca
    19141 aaaccattta taaaaatcat ccataacata taaaagatta ggagcattat tgatatctag
    19201 ttggttcaat ttggttaaat ttttacattt atttgaaagt attttattgt attttggctt
    19261 aactaaagag taataattat ctattgtatt aaattcgtta tcaactaaaa ctccaccaat
    19321 agaaattaat tccgcaccat tatattcttt tggtttattt ttattatcat ctagtatatt
    19381 aaattcaaag tctataaata acttgtattt cataaatcta aagcacatcc tcaggtaaat
    19441 tatttattga gcctaagcat cataagaatc aatagatata atgactctaa acatcaaagg
    19501 ttcattacaa cttttattta tttcataatt taattcaaat aaatctttta agatataatt
    19561 tataagtatt ctttcccaac ccatttttaa attaacttta gagtctatta atatattttc
    19621 tatcttttta aatatttcta tatttgctgg tattatactg agctcaatat tacttttaaa
    19681 cgggttagac tgtaaatctg ttataagtat attttttaat tcctctgtaa gttcagaaat
    19741 taaactatca cctatgtatt tttttatgat ttcctctcta atttctttta aatttagcaa
    19801 tattagtacc tgctacttac atagtagctt ttcctttcct tttaatacta ttattcattt
    19861 ttgaatctta tttagatata ttttaagatt aaaagtcttt agctatataa ttttttaccc
    19921 atttttaact tatattaaca tattacaggc ttatatctcc accctgttta cattgaggat
    19981 ggagtatatt gcctattttg ataaaaatga taggttgcta tttgcctatt cctttttctg
    20041 ataatttttc taacatatct ttggtcattt tatctaaatc ataactaaac ttaaagttcc
    20101 attcttttac tgcactacta ctgtctagag agttaggcca agaatcagct atactttgtc
    20161 ttacagggtc tacatcatat tctatcacaa aatcaggaat atattttttt atagaatcag
    20221 ctatttcttc aggagaaaag ctcatagcag taatattaaa agcatttcta tggatgagtt
    20281 tatcagctgg agcttcgatt aaatccacta ttgattgaag tgcatcaggc atatacatca
    20341 tatccatttt tgtaccttct gctatgtaag atttatatct cttatttttt aatgcctcat
    20401 aatatatatc aactgcataa tctgtagttc ctccaccagg aggcgtaaca taagaaataa
    20461 gacctggaaa tctaacacct ctagtgtcta ctccaaattt tgagtgataa taatcacata
    20521 gtaattctcc agaaacttta gtcacaccat acatagtatt aggtctttgt aatgtatctt
    20581 gaggagtcat attttttgga gaattttcac caaaagcagc aattgaacta ggtgtaaaaa
    20641 atttacaatc caattctttg gctatttcaa gaccatttat taatccattc atatttaagt
    20701 tccaagcttc tagaggttta ctttcagcaa ctgcagaaag taaagatgct agatgaatta
    20761 tagtatctac atcatatttt tttgcaattt caaaaaaacg attcttatct gtaacatcta
    20821 atatctcaaa tataccagat tcacatactg gattaccttc ttttactctc cttgaactag
    20881 cgattacatt ttgttctcca tactcatttc taagctttat tgttaattct gaacctattt
    20941 gtcctaatgc acctgttata agtatttttt tcaattttac aacctcctaa gggtttaatt
    21001 tatgtagtac tacttatttt tattttagca aatcttttgt ttaaatacaa agaattaaag
    21061 ataataatat acgacttaat tgaatgaagt gcagtaagtg cgtaaaaatt taaagctaat
    21121 atataatggt ctattgtata acaataaaag agtagattaa attattatat atagattgtg
    21181 tgactaagtc acagaaaata gagctaattt aatatataat aaaagcatgt caagtaaagc
    21241 tttaaattaa agtaacttta tataaaaagt aatataaatt gataaaatta taaatttatt
    21301 tatagtgaat ataggttgga ttttatagat acaaaaatag tatatatgat atgtagacca
    21361 ttagcatgtt taaagtagca aaacatataa aataaaattt gaaaggaagt ataaaaatga
    21421 caagaccatc aatatatcat agccaaggat acacttgtgc agaggcatta ataaagtctt
    21481 ataatgagga acacaacaca gatataccaa tctcaatagg aagtggtatg ggggttggaa
    21541 tgaatgttgg aagtgtttgt ggagctgtaa atgctgctgt tgttataata gggtatttaa
    21601 atgggcgaaa tagtaattta gatgaaaata tagcaaggaa gtattcaaga gagctattga
    21661 atagagtaag aaataaatac agctcagaaa tatgtgtatc tcttaaaaaa aataaagtaa
    21721 cttgtgaaga aataataaat ttcacatatg atgctctaaa tgatatgcta aaaaatcaaa
    21781 aataattcta agaaacaagt attttacatt cgatagaata cttgtttttt tatgatattt
    21841 ttaataagta ttagtttatt ataattttta aatcaatttt attatatttt aattgaaata
    21901 atctactttg aaaattacta actgacaaaa gaatatgatt atagtataga aaaaatgtaa
    21961 attatttaat attaagtgag agtatatgct tacctatata aaatcgtata aattaatggc
    22021 taaatttata aattataaag aaatatatag gaaaataaaa gaattaatta gtataatata
    22081 aagttaaaaa gtgaaaattt atataattta tttataaagt aaagaaaaaa tagaaatttg
    22141 taataaaata aaaagtttat gacataatat ggtataatta gtaaaaatat agagattgga
    22201 ggaattgctt tgtttataga tgaagaatta gaaggttata tattaacatg taaaatatct
    22261 gaagacttta aaaatatacc tgaatatagt gatgaagagt tttatgttac agtctataaa
    22321 gatgaaagtt ctgactctgg gtactatgct ttattagaaa ataaagaaga aagagttgta
    22381 tgggatggag aagttgttgc caataatatt tttaataacc tttggattgt aataaataag
    22441 gttaaaactg gataatagtc taattatata gtatttgtaa tattttaaat gaatttttac
    22501 atatttgaga tgagtaaata acaaagatta ttcgatactg gaggagtaat tcaatggaat
    22561 atagttatag taagatgaac ttaaaaaaag gggatattgt agaggtaaat ttagagaaac
    22621 aagccaatgt aatattgtta gaccatataa attatgtgaa atttaaaaat caaagaaatt
    22681 atgattacta tggtggattt gcaaagaaaa atccatgtag aatgagagtt cctaatactg
    22741 gaacatggta tctagtagta aatcaagatg gaaatagtgg aatagtaaac ttttcaatca
    22801 atacaattca aaattaattt tagaatattg gatattctta ctttttgtac tttttatata
    22861 gttaaaataa aattaataag caattattat aaaataatgt gggtgcctca aaatgaattt
    22921 tataattcac gagacactct tttttatatg aactcaaata tactttatca tttcaacaat
    22981 gaaaaaaagg cgtatctgtg ttttgagata gcctcattta tcatatatca tatatagaat
    23041 tttaattatt cttaactaaa attttttcca taggttatct gtacaattaa aatatttatt
    23101 gttagcatac agctccacct gtaaggtgta aaagagcctc tagtatctct tcttttcttt
    23161 ccaaaacttc atctgataaa agcatttcta taaatttatc agcaccgatt ctatcgatag
    23221 ttattccaaa acgttcacct gtgttaccct gttctctaaa taaaagaatt gctttttcaa
    23281 ttaaagtcat aagttcctct tttgaaaata atctatcaat ctgtgttcca ggacgaactg
    23341 attttcccca tttccctcct atatagactt tataaccaga ttctttttct tcaatactat
    23401 caaaattaca actttctata cacttaccac agttattaca tagattacta tctatttcaa
    23461 gtttaccttt atctgttaat ttagctgctt taacaggaca gacctctaca acagcacatt
    23521 ttttacaacc aacacaaagc tctgaatcat agtcaggtac acgttgacca acaattccaa
    23581 gatcgtttag gtcaggttta atacagttat tagggcatcc accaacacca attttgaact
    23641 tatgaggtag ttttacatca taccaatttt tgtaaaattc ttcgtgtatt tcagcagcaa
    23701 gtgcctgtgt atcagctaga ccatgaacac aaacagtacc tttacaagcc acaacaggac
    23761 gaacccttga tccagttcca cctgttatta gattttcgct agcaataaat tcacttagag
    23821 cttcaatatc ttcaaatttt acaccaggta attctactgt tagtctagta gtaaatgcta
    23881 actgaccgtt tccgaatttt tcagcagctt ctgcaatttt ttttgcttgt gatgcattta
    23941 ttacaccatt tacagttatt atacgtgctg caaaatgttc tccatccctg cttggtagaa
    24001 aacctctacc ttttacttcc tttttttgtt ctgctgtaac attactcata tttactcctc
    24061 cattacctta agatttggat aaaatagtat tccaccttca agaactttcg tatttgtata
    24121 gccaaagcgt cttaagcgat tttgcgccat atagctattt ttacctttag cacatataag
    24181 aagaattttt tcatccttag caaggccttc aatttctcca ttaatttcac caacaggaat
    24241 ataacgtaaa ctaggaatag aaggagcttt tgaaacatca agtttagtcc aactgtcaaa
    24301 atcctcaatt tcgtcaagta aaacactatc aagttctcca ttaagtttat tttgtaaaac
    24361 atttactgcc actacaaaag ggtgaatagc tgttgaaaaa ggtggtgcat atgcaaggtc
    24421 catactttct aatgaataaa ggtcagcgcc taaagttatt gcagtagcag cgatatctac
    24481 tattttatca accgctccag gtcccataac ttgaacacct aataattttc tagtattttt
    24541 ttcagcaacc attcttataa taaaattaga tgcacctgga taataatgag ctttatcatc
    24601 agtagctatg gttacagagc aaacattata accttctttt tcagctattt ctttacttag
    24661 acctgttttt cctgcattga gctcaggtaa ttttactact gttgttccaa gaacaccatt
    24721 gtaagtttta gattttccag atatattttg tgcgcaaatt ctaccctcat gatttgcaga
    24781 tgaccccata ggtgaccatg taggtttatt tgttaaagaa ttttttacaa aagcacagtc
    24841 tccaactacg tatatatctt tgtcatttgt aagcatatat tcatctgcaa taattgtatt
    24901 attaggggca aattctaaac ctgtgtcttt tagaaaacct gtgttaggac ggattccaac
    24961 tgacataacc actaaatctg ttttaatagc tctattttta gtacgaagtt tttcaacttt
    25021 attttcacct tcgataccta caacctggtc acctgtaaaa atcattatgc ctttatcagc
    25081 catatgattt tcaacgtatt cagcaaaatc agtatcaaat ccaggcataa catgttcagc
    25141 catatcaaca acacttacac gtatacccat tgcagaaaga ttttcagcaa tttcaagacc
    25201 aatgaaacct ccaccaataa caacagctct cttaataccg ttttcaatag aatctcttag
    25261 ttttatagca tcatttggag tacgcacaaa gaatactcca ggtaaatcta ttccaggtat
    25321 tggtggtttt attgggtctg cccctgtagc aattacaagt ttgtcatagc ttagattttc
    25381 tttttctcct gttgaaagcg ttttcaaagt tacttgtttt gcatttctat caatagatgt
    25441 aacttcaact ccacaacgaa cttctgctcc tgttagttta gaaaaacttt caggtgtatt
    25501 tacgattaaa gatgatttat cttcaattat cttaccaacg taatatggaa gaccacaacc
    25561 tgcataagaa atatcatcac ctttatttag tattgtaaca gagcaattat cacccatttc
    25621 acgttttatt tttgcagcag tttttgttcc agcagcaact ccacctataa ttaatacttt
    25681 cacaatatat cacactccaa tctactttat aactctataa taaaattata cttcttgaca
    25741 atatatttgt aaaatactaa aatattaata aaatcataag catttactaa tgtttgctaa
    25801 ggttgtgata atatgacaat tcgtagtctt gaaatctttg ttaaggttgc tgaatgtggt
    25861 aaaatgagtg aagtagcaag aaatatgtat attacccagt catcagttag ccaagctatt
    25921 tcagaaatag aaaaagagta tggtgttaag ctatttgata gaatttcaaa aaaattatat
    25981 ttaactgagg cagggaaaaa acttcttgga tatgggaggc atcttttagc tgtaaatgaa
    26041 gaaatgaatg attgtatgaa gcattgtgca aaaaatatcc gtataagagt tggggcaaca
    26101 gtaactgttg gtacatgtgt aataagtcca ataatgttag aattatacaa ggtaaatcct
    26161 cttatagaac ctgaagtatt tgtagaagat acaagactga ttgcaaaaaa attacttaat
    26221 agtgaattag atattgcgat tgtagaagga aaaattaagc acccagatat tgttacaaaa
    26281 agcattatta atgataatct tgtacttata tgttcacaca agcatgagtt ttataaaaga
    26341 gactctataa aagtttcaga actttcaaat caaccattaa ttatgcgtga attaggaagt
    26401 ggtacaagag cacaattaga aaagcaatta aaagaattaa aaatcccaat gaatattaga
    26461 tggtcatgtt ataactctga agctatatta agagcagttg tagataattt tggcattgca
    26521 gttatatccg aattacttat tgaggattat ttaaaaaagc atcttttgtg ggcttgtgat
    26581 attgaaggta ttaatttaca taggacattt gatattgcat atcatagaag caagtttttt
    26641 acagaaaata tttcagcatt ttttgatatt tcagtagaat atgggaaaaa acaagcgaga
    26701 aagaagagta gaagtgtaaa cagtttataa tatatctaaa taaaaataag agtatatcaa
    26761 tatactctta tttttattta gatatattag cctatattaa cgccaaaatt tttacacaat
    26821 cctgcaagtc catcctcaaa tccagaacct aaagcattaa atttccattc tccattatgt
    26881 ctatatagtt ctgccacaac tattgctgtt tctatgctaa aatcttcacc caattcatat
    26941 ttaataagtt cctcattagt ttcttcatta tatattctta tatatgaatt ttcaacttgt
    27001 ccgaaatttt gtcttcttgt aattgcttcg tttatagtaa cactaaatga tattttagca
    27061 atattttgag gtattttaga taagtctaca tttatttgtt catcatcacc atcaccaaca
    27121 cctgttctat tatcacccat atattcaaca gctccagaag cgtgttttaa attattatag
    27181 aatataaagt ctccatcatt cgttactttt ccatcagttc cagttaaaaa tgcagaggca
    27241 tctaaatcga aatcaaagcc accatcatat ttattaatat cccatcctag tcctactatt
    27301 acttttttta gaccagggtt actttttgtt aaacttactt tttgtccttt tgctaaagtt
    27361 atacccattt aaaccaactc ctcattataa attttttatt gtaattatta cttatatgta
    27421 ttaattaatt cacgaagctc ttcattttga ccaattccta aagcattaaa tttccattct
    27481 tcatttctac gataaatttc tcctgccaaa actgttactt taccagaaaa gtcttcttga
    27541 agattatatt taaataattc ttgcttggaa tttgaatcaa ttaatcttat aaaagagttg
    27601 ttcatttgac caaaatcctg gtctcttttt ttagctttgt atatagaaac tccaaaaact
    27661 attttatgta catattcagg tatgtcttct aaattaacaa ttatttgttc atcatcacct
    27721 tcaccttttc cagttaagtt atctccagtg tgtataatag ctttagaagg gtgtttaaga
    27781 tttccaaaat aaaccaagtc acctctaaca ttcattttat cttggttagt caatgctatt
    27841 gcaaatgcat ctaggtcata atttttttta cccaatttat tcatatccca tcctaagcct
    27901 actactagat tttttacagg attattatct tttactaagc taactctttg tcctttttgt
    27961 aaactaacac tcattttaag ttctcctttt tatattttta gttttattga tggtatcaag
    28021 tataagaacc atattagcta tattatatac gtatttaggc taagttggct atatttataa
    28081 attatttatt atataactac atgaatattt tataatttaa acatattgac attatatgct
    28141 ttaaattatt ttgtagtttt ataatattta aatttgtatt tgattgttat aaagtaaagt
    28201 aagtaataaa gttagactca ataattctaa aatttctaag catactatct aaatgagaac
    28261 ggatttggaa atacttgtat aaaacaataa ttgatacatt taatttttat cttaaaaaca
    28321 acaattataa tatataaata gcaagtataa tatataaata gcaagtataa tataacatat
    28381 aaaaagttga atttgtatat gttaattata cttgctattt atttgttagt tattctattt
    28441 ttttaaatcc attacctaaa gcttcatgta tatctgtaat tataataaaa gcattagggt
    28501 cgacattttt tactaatttt ttcaattcga caacttcttt cttttcaact actactaaaa
    28561 gtacattttt attttctcca gtatatgcac cttctccttt tagaatagtt gcacctctat
    28621 ctaaatcttc cattattttt ttacttatat cttttgaaag gtcagatata atagtgaatg
    28681 atttggaata attaaatcct tcaataagca agtcactaac ttttactaaa atgtataaag
    28741 ccacagttga ataaagtgca atttcaacct gtctatttac tatacctgat aaaacaacta
    28801 caacgcagtc tacaataccc attaaaacag gtatactaaa tgtaggaaaa tatttattta
    28861 gtaggagtgc cattaaatca gttccacctg tagagccatt tattctaaaa ataagtcctt
    28921 gaccaactcc cattaaaata gaaccagata taattgcaag atacatatca tttgttatat
    28981 ctaatgtagc catatttgca gtaagcttaa gtgctatggt aagaaaaatt attcctaaaa
    29041 ccgttttaaa acaatctttt tttgaaagta ttttgtaagc aaatatgaat aatggaacat
    29101 ttaaaagtaa attgacaatc caaagttcta caccgaataa tgaatttaaa acaactccaa
    29161 gtcctgttat accaccagca gcgattgcat gtggattaaa aaataagtta agagaaatgg
    29221 ccattaatat acagcctaca attaatatta aaatttctga aaaagttatt ctatcttttt
    29281 tcaataacat cactccttat atatagatta taatatatat tatatagttt ttccaatttt
    29341 taataaaaga aataaaaata tattataaaa acaatttgat tggaattttc agaaaattaa
    29401 tgctataatt aaaagtaaat ttaaagggag gttataaaat ggctaaatta actctagaac
    29461 atataaaagg aaatacatat tatattccac tccctacaat agtaggtgta tacgtagatg
    29521 gtaaggatgc aattttaatt gacagtggaa ataataagga tacagctaga caagttttaa
    29581 gattattaga agaacataat ttaaatccta aattaataat aaacactcat tcaaatgcag
    29641 accatatagg aggaaatgca tatttgaaga atcaaacaaa atgcaagatt gctacgacta
    29701 aaattgaagg atattttaca gaaaatccaa tattagaatc agcattttta tatggtggct
    29761 atccaagtaa agcactgaag aataaatttt tattagcaaa ggaaagtgaa gttgattata
    29821 ttataccttc aaatggcaaa attgtagata cagaacttga agcgatttct cttccaggtc
    29881 attattttga aatgattggt gttagaactc cagataatgt tttgtttgtt gcagatagtc
    29941 ttacaccaga gaatataatt actaaatatc attttttctt cctactggat atagattcac
    30001 agtttaagac actagaaaaa ttgagaatgt tagaggctga tttctttgtt ccaagtcact
    30061 ctgtcaaaac tacagatata aaaagtttaa ttaatattaa taagaagaag atggaagaaa
    30121 taatagataa tattaaaaag gtttgttatg agccagttat gattgatgaa gttattgaaa
    30181 aaatgtgtga tttgtacaat gtcaagcttg atgctaatca atatgtgttg gttggaagta
    30241 caatacgttc ttatataact tatttatatg agaataatat ggttgaatat atatttgatg
    30301 gtggtaagat gatgataaaa gctgcgtaaa tagtaataat tttcaaatta tatgatgaaa
    30361 ttgttttagt atgactgtta tttgaaaagt aatataaaaa aatttatata aataagctaa
    30421 gatgattgat ataaagttac tgataatttt aaggtaatat atacgttact ataatattat
    30481 gttattattt gtaaataagg ggataattta taagcaaatt aaagacctta atttacagga
    30541 ggaatagtgt atattatgaa taaaaaattc aaaaaattca gtaaaaaact aagtatatta
    30601 attttagttt tgactatgtt tctttttaat aatttaactg caaatgcaca gattaaagaa
    30661 gattcaataa taggaattga tagatatgaa acagcaggac ttatagcgga tagacaaact
    30721 tatgatactg taatattagt taatggagat aaaaatttat ctgatgggct ttcatcaagt
    30781 ggattagctg gagctattaa cgcaccaata cttttgacta aaaaaagtga aataccaaaa
    30841 gctactttaa atagactaga taataagagt ttaaatgttg taaaaaaagt atatataatt
    30901 ggtggttata atactattga aaattcagta gaaaaagata taaaaagaaa aggtattcaa
    30961 gtggaaagaa taaatggtaa caatagaatt gaaactagtt ataatgtagc taaaaaaata
    31021 aatgaagtaa gtagtgtaaa agaggtaatg cttacaaatg gatttgtagg agaggctgat
    31081 gctatgagta tagcacctgt agttgcaaaa aataaaggag ctataatact tacagatggg
    31141 aaatcagttc catttaagac tgaaggttta aatgtttacg ctataggtgg caaatctgcg
    31201 ataaatgagg atttagtaaa tgaaactaaa gcaattagaa tcggaggaaa tgatagattt
    31261 gagaccaata aaaaggtaat ggaaaagttt tataatggag ctacagattt ttatataaca
    31321 aatggatatc aattagtaga tgcactaaca ttatctcctt tagccaaaga aaaaccaatc
    31381 gttttagttg ctgatggaag taataaaggt attttaaaag gagctaaaag tataacaaaa
    31441 gttggaggta ttgatgccaa tatatataaa cagtgtttag atatgattaa atataataat
    31501 atggatatga ctccaaatat tttaaaacac ttaacttcag ttgaaggaaa tgaagtttct
    31561 gaaatactta tagaatcaga taatttaggt gtggttgttg aaaagacgaa taccaataaa
    31621 tttgagtttg attacgtaag tgtaactaat gaaaaaaatt gtactttttc tgtatataaa
    31681 gaaaattctt ctaataatat aaaaaatgga aagctagttg taagtgctaa gaaaaaaata
    31741 gataagaaag atagtgattt gcaagatatg aatggcgaca atatgataaa tgcaaataaa
    31801 gataggatgg taaatgtgat aaaaattgga gttcccgata aaatgtattc taattttaaa
    31861 gtagatgttg aaagtggttc agtagaactt tataatatta aaggaggagc tactgttgat
    31921 gtcaatgacg gaattgctaa cattgttgat aacaatgtaa caaatccttt caatataaat
    31981 actaatagtg ggatttcagg tgtaacagct gaaactatat catctgaaat aaaatttaga
    32041 gcaaacaatg gaattgtaaa tgtaacagct acaaatataa atggcaatat aagtttattt
    32101 ggaagcgata ataaagatac ttttgatgga atatttaaat taaatctgaa aaaagaacca
    32161 tcaaatttac acttgaagtt aattggaaat gggataaata aattgccaga aggttggtct
    32221 aaagattata ttttaggaaa tggacaacca attattgaag ttaaaaataa tggcataaat
    32281 aatatatcaa ttggagaata aaaacatatg aaaataaagt ttatatagtt ttaaaaatta
    32341 tagaatttta aaatatttat atatattctt taaataaaaa attatttttt aagtgataat
    32401 taagtgttta tcgataaggc tatggttgta aaaatcatag ccttattttt atattataaa
    32461 taaattagag tatttatcaa ttcatagtag ataaaattga aattaaatat aacaacaaaa
    32521 aatgaaaatt acaattaatt taatgttaaa gactcaatta tttggatgtg gaatggatag
    32581 tacaagtagt atataaaaag tattgactgg acaaataact atattttatt ttaaatatat
    32641 aatataatgt aataaaatat atcaaatgta gaaggtgata acctatgaaa aaaataacaa
    32701 taaatgatat tgctaacttg gcaggagtat ctaaaagtac tgtatcaaga tatctaaaca
    32761 ataaagatat cagtgattct actaaagaga aaataaagac aataatagat gaatatggat
    32821 atgagccgaa tgcatttgct caaagtttga gagctaaaaa aacatatttt attggtatta
    32881 taacaccgtg tttagattct tttgtaaaat ctaaaattat gatggcaata gatgaagaac
    32941 tcaaaaaatt aaaatataca tcactaatta ttaatactaa tagaaaaata aggtcagaaa
    33001 tagatagtat atcaaagtta gctagtctaa aagttgatgg aataatacta attggtaccg
    33061 aaataactaa agaacataag aatgaaattg aaaagttaga tataccgata gttgtagttg
    33121 gacaaaaagt tgatggtatc aatagcatag tgaatgatga ttatggagca ggctataaaa
    33181 tgggtcaata tattgctaat aaaggttaca aaaacattgt atatttaggt gttgatgaaa
    33241 gtgatatatc agttggttta aatagaaaaa atggagtact taatgggtta aaagataaag
    33301 ggtatgatgc aaaagtattt tatactgact ttgaccaaga aatgtctata caaagaagtg
    33361 gagaaatgct agaaagtgaa aatccagata taataatatg tgcaactgat aatatagcaa
    33421 tagcaacaat gaaagaaatc aataagagag gtaaaagtat accacaagat atatctgtag
    33481 ctggatttgg gggatatgat gtattgtcta ttataagccc taaacttaca acaataaagt
    33541 ttgaaaataa aaatgcaggt aaagtagcag caaatacgat agtaaattta atacaagaaa
    33601 gaaaagaacc actattaaag gagattaaat ttgaattaat agaaggtgaa agtacaataa
    33661 ataaaaatta agatacacat tacatatatt agtaatgtgt atttttttac taaaaaaact
    33721 ataattctaa aaattaggaa aacttttttg aaagaaatat tgcatctgaa ataaatttat
    33781 gctaatcttt aattaaaccg gtttcgaaac cggtttaatt aaaccgatag aatagcaaaa
    33841 tgagtgcaaa aataactgat tgtaacaaag tatcaaagta attattggag tacataggaa
    33901 taaacaaaat ataaaagatg tagcacattg tgtaataaga ctaagaattg ttttagatag
    33961 caataataaa gcaaatataa aattataaaa gaaaaggaat aaaaatatgt acaaagagcc
    34021 taaatataga accatattag aatcgacaaa agaagaatta aataaattaa gaaatatatc
    34081 tttaaatgat aaatataaac cactatttca tatacatcca caacatggac tacttaatga
    34141 cccaaatgga ttagcatatt ataatggtaa gtaccatgta ttttatcaat ggtatccata
    34201 tgatgcaact catggaatga agcattgggc ttatgtaagt tctgatgatt ttgtaaactg
    34261 gaatagagaa gatgtagcat taataccaat cgaaagttat gaatctcatg gagcatattc
    34321 aggtaatgcg atagaggtag atggaaaatt gcatatgtat tatacaggga atataaaata
    34381 tagtgcagaa gatagatatg catatcaaaa cttagctata atgaacaagg atggtaaaat
    34441 aactaaatat gaaaataatc caatagtaag tgaaatacca aaaggatata caggacatgt
    34501 aagagaccca aaagtattta aaagaaagga taaatacttt atgttacttg gagcacaaac
    34561 aagtgataaa aaaggagtta taatagtata tgaatctaaa aactctatag attggaattt
    34621 taaaggagaa ttaaatgtaa aaaacataga tgaagatttt ggttacatgt gggaatgtcc
    34681 agattatatt aatatagatg aaaaagatat attaatattt tcaccacaag gagtagaacc
    34741 taaaggattt gattatcaaa atatatataa tgtagtatat gctattggta atatggattt
    34801 agataattta acatttgaaa tagatacaat gaaagaactg gaaaaaggat ttgatttcta
    34861 tgctccacaa acatttataa aggactcaca aataatacta tttgcatggg ctggaatggg
    34921 agaagtttta taccctacag ataaaaacaa atgggcacat tgtctaactg ttccaagaaa
    34981 attaaatata aaaaataata agctattgca aatgccagta gatgaattaa ttaaattaag
    35041 atatgatgaa acaagtgggc aaaatactat aaagaataat attaatatta tagaaaatga
    35101 tgaaaatgta tatgagctta atattaatat aaaaaatatt gacagcaata aatttgggct
    35161 ggaattattt tcatcacaag atgaaggtgt aaaattagaa tttaacaaat taggaaacat
    35221 tgtaacttta gacagaagca actttaaaaa agttttcggt gttgaatatg gaacaaatag
    35281 aaaagaatat ataaatattg atgaaaatac taatatcaaa gtactagcgg atagaagtat
    35341 tttagaaatt tttataaatg aaggagaagt agtatttact agtagaatat ttgctaaaga
    35401 aaattctaat caaataaggg tttatagtga taaaatagta gagtatgagt atactaaatt
    35461 taaattaaag caaggtattg aattataaaa acacattata aggggtagaa aagatgaaaa
    35521 aagtaattag tataggagaa gctttaatag actttatacc taatcaaaat ggtggtaaat
    35581 taaaaaatgt atcagaattt agaagagtag caggaggagc tccagcaaat gttagtgctg
    35641 ttgtagcaaa gcttggagga aaatcgagtt ttatatctaa gttaggaaaa gatgcatttg
    35701 gtgattatat aatagatgta ttaaatgaag taaatgtaaa tactgattat gtattgagaa
    35761 caagtaaagc aaatacagga cttgcttttg tatcattaaa agaagatggt aatcgtgatt
    35821 tctcatttta tagaaatcca agtgcagata tgcttttaga agctgatgaa gttaaaaaag
    35881 agtggtttaa taattgtcat atcctacatt tttgttcagt agatttaata gatagtccaa
    35941 tgaaattagc acataaaaaa gcaatagaat acgcacttga aagtaatagt ataataagct
    36001 ttgaccctaa tataagatta cctttatggg atagtgagca atcttgtaaa aaggcaatat
    36061 cagaattttt accttttgct catattgtta agatatctga tgaagaatta gaatttataa
    36121 caggagaaaa tgatatagaa aaatcattac ataaactctt tgtggggaat gttgaactag
    36181 tattatatac aaaaggaaaa gatggagtag atgcatacac taaaaaagta aaaggtatgt
    36241 gtaaaggggt taaagtaaat gcaatagata caaccggagc aggagattct tatataggtt
    36301 catttttata caccttattg tataaacaaa taacattgaa tgatataaaa gaaatgaaac
    36361 aagaaacgtt aaatgagtat ttagaatttt ctaattatta tgcagctcgt agtacaacta
    36421 ttaaaggtgc gataagttca tatgcaacaa aggaagaaat aactgaattt ataaaaaatt
    36481 tatagtagga atgagtaata ggttttgaag gaagtaacat gtaaagagtt tttaaggatg
    36541 tttactatga aaataattaa catataaaaa gcaataagga ggctgtctca aaatagagat
    36601 aagcctcttt atcattgttg aaatgataaa aaatatttta attattgtta ctttttagaa
    36661 gaatatatat cttattttaa ataagcaaat tatgtaagat ttatttatat tatcaatact
    36721 ttacttggag tattatgtct ttagcagtta tctaattcaa ttgaattaga taaaatataa
    36781 taaatttgtt ttgcaaattg acgagaatgt tcttcttttt ctttattcat aaaattaggt
    36841 ttacctaaat cacgttcaac aagcattcct atatatttta actgtgaatg cttacagtag
    36901 cgcttcatac cattttccca aatatcagca cccttttcag gtctatatcc acatgttgta
    36961 ataagtgcta ctgattttcc tgcccataga gcggggcctt tctcattacc atagtattta
    37021 ttcattccat acaccaatct gtcaagtagt gctttcattg gagaagtgca gtaccaagaa
    37081 taaattggag tagcaaaaac aattaaatca cacataagaa ttttcttgaa aattttctga
    37141 acatcatctt tacaataaca tccaaaatca aataagttat cctgacactt tttacaagca
    37201 atacatggct ctattttaca atcatataac catattactt caatatttga attataattt
    37261 tctaattcct caataaaagg ttttaaaata gcagcagtat tacctttttt cttaggactt
    37321 cccataagaa tgcatacttc catattgata cctccacagt attttaaaat agtttttagt
    37381 gcttaatata gttttaggat actatgagaa tacgttaaca acaatacact ttgtatattt
    37441 gtaataaaat tgaaacaaat tgttttatca ataaaagttg gaatgtatct ataattaaaa
    37501 atattttagg tatgttttta catatatgtg tgtagttaac tatggtaatt tattgtaaaa
    37561 ttatcttata ggattataat tgcttaattt atgattatat ttaaaatctt ggaggtaaaa
    37621 aatatgtact caaatgaaga ctataaattt atagaagaaa atgcaccatg ttatatatat
    37681 gatgagacta atataattga aaaatgtaag gaattgaaaa ataatatttt aggttttgat
    37741 tttttatatt ctataaaaac aaatccatat aacaaaattg taaaaagcat tgcagagcaa
    37801 ggttttggag cagatgcttc ttcaactaat gaagttatga tttcatcaaa atgtggagtt
    37861 tctaaagatg atatttatta ttcatcacca ggcaaaacag agattgatat agaaactgtt
    37921 ttagataaat gcataattat tgcagatagt attacagaaa tagaacttat aaataagata
    37981 tctaaaaagc ataatcagaa agttaaaata ggaataagaa taaatcctga ttttactatg
    38041 gatgatgata gtgctaaatc aagcaaattt ggtatagata tagaagatat gagcagtgtt
    38101 tttaagatgt taagtatgtg tgattatgta tctgtagttg ggattcatat acatattaaa
    38161 tctcaggtat tggattttga aaagttagga cattattatg aaaaatgttt ttttatagct
    38221 ttaaatttaa ataaaagtaa gtatattaat attgaattta taaattttgg tagtggactt
    38281 ggagtagctt atgataatct tagagaaaat ccacttaatc ttaaagagct ttcaaaatta
    38341 actcaaaaga ttgcttttac taattcaaac acactaaaat caagacttct tattgaatca
    38401 ggacgtttca tagtttgtaa atcaggtaat tattatgtta aaattgtaga tattaaagta
    38461 tcaagaggga aaaaatatct tattgtaaaa aatggactta atggatttat gagacctatt
    38521 atttctaatt taattgaaaa tattacttgt ggagtagaat tagaaggtca agagccatta
    38581 tatacatcaa atcatgcctt ttctctttca gtattaaata atttaaaaga agaagagtat
    38641 gtaaatgttg ttgggaatct ctgtacatca ttagatgtaa ttgcaaataa tgttaaattg
    38701 aaaaaagcaa acataggaga tttgatttca attagtaatg ctggaagtta ctcctattct
    38761 ttatcaccgc tattattttc aagttatgaa tttcctaaac aatattataa aagaaaagat
    38821 ggatatattg agtaaacaat agcataaatt aataaactta gtattattga aaaaatttaa
    38881 aatgcagggg gtgtaattct atatggaatt gtggaaaaga aatttatttg tatgttggat
    38941 aggtatgttt tttagttcta tagggatgag ccaaatagca cctatacttc cattatatat
    39001 taaacagttg ggggtaactg atgttagttt aatacaacag tattcaggta taatttttgg
    39061 atgtaccttt gtagtagcag cattcttttc gccaatttga gggaaagctg ctgataaata
    39121 tggaagaaaa tcaatgcttt tacgtgcaag tattgggatg ggaatagtta tatttaccat
    39181 ggcgtttgtt caaaatgttt atcagttatt aggattaaga atacttcaag gagtttttac
    39241 gggttatgct actgcatgta ctactcttat tgcaacacag acagataaaa atcattcagg
    39301 atgggctttg ggtactcttg caactgcatc aactactggc tcattaattg gtccaacagt
    39361 aggaggatat atagaatcaa tcttaggtct taaaagtaca tttattataa caggaggatt
    39421 gttgtttgta tcatttatca tctctatttt atttgtagta gataatttta aacctaaaga
    39481 aataaaagaa tcaatttcta tacctaaaga acaattaaat atattgccaa ataaattttt
    39541 aattgcatct atttttgtaa ccacattcat tactcaacta gctttatact ctatagaacc
    39601 aattgtaacc atatatatat cacaacttac aaattttgca tcaaatgtag ctttaatagc
    39661 tggattgaca ttttctgcat caggattagc aaatttatta gcagctcaaa aacttggaaa
    39721 aatgtcggat aaaataggtc ctcaaaaagt attgttaatt tcacttttat gggctgggat
    39781 tatatttata ccacaagctt ttgtaaaaac tgcatggcaa ctgatgttgt tgagattttt
    39841 attagggttg tcagttgcag ggcttaatcc ttctgttaac agcttgctta aaaaaattgc
    39901 accagaagaa tatgtgggaa aaatatttgg atataatgca tctgcccagt atataggctg
    39961 ttcatcagga gcatttttag ggggacaaat atcagcacat ttaggtatta gaacagtatt
    40021 tttttcaaca agtttattgt tgtttaggaa tgcactttgg atgtataaat ttactggatt
    40081 gtttattaaa gataagacta aataatcata ctatttacat ttctaatttt atgatgtaaa
    40141 ataaatattt tttatgtaat ttatcataga attatataaa aaataaccct atggtaaaaa
    40201 ttggaaaata ttattatcga caaaatcttt gacttaaaaa ctatattgcg atagtattaa
    40261 tttaataaaa gtttgagagg ggcgtaaggt tatgacaatt tcaaaaatac cacaagcaga
    40321 attaaaagtt atgaagttta tttgggaaaa aaatgataca gtaacatcaa aagaaactat
    40381 tgaagctatg gaacgaaaat atggttggaa acaaacaact acattgacac ttttatcaag
    40441 acttgttaaa aaacattttt taagtgcaga aaaaatagat agatacactc attatacaat
    40501 agttgttgga cataaggagt atttaagtgt tgagacaaaa gattttttaa gcaatataca
    40561 cgacaattct ttacagagtt taatttcagc actacatgat gatgaagttg ttgataaaga
    40621 tatgttggat ttatttgaaa gtcattttaa aaatttagaa gaagagtaat tatatcagga
    40681 tagaactcta agaatttaat taatctatgg ctgaaaacca taaatggtat tatttaatca
    40741 gctactcact attcataaag taatattaaa taggttctct aattagtaaa atgcctaaaa
    40801 taattggaat agggagtatc aagttaaatg ataccactta tttaaataag aaatgatttt
    40861 taaaatttaa aataatttta taacttgtca atattcatta atctaaagta ttatttctat
    40921 ttaaccatat caaaatatat tttactattt ttaattatta caatataaac ctgtcttttg
    40981 ttattatagg taaactaaaa gtaagaaatg atttttatat ttttaaactt tattattggt
    41041 aacttatctg taaatatttt aaaatgtact atagaaagtt gttaaaaata ttaaataatt
    41101 atattaaatt taagtgtgtt ttttatgcta taattagtat gtatttttta tgatatattt
    41161 tataaaaaat ataatttaat catttttgag gatattatta tgttagatgc atttataaca
    41221 attgtttctt ctattataga aatatggtca tgtaaaaaag tttttgatta tactagtcag
    41281 tcaaagaccg acttaaaaaa actaaatatg tattttctct tttctgtttt tctcattatt
    41341 tcttctttat atataaatat aggagctaat agtagaatct tgatatgtat atttgtaatg
    41401 ttcgttttct ataagtctaa ctataaggtt aatatatata aatgtctggt aatctcattt
    41461 ttttattggt taatattaat aggtataaat ggattaagta tgttattagt agcaacagta
    41521 agcaatttgg ataatatgaa tgttttactt agtggcagtt tatatagata tgaagcaata
    41581 ttcttgggaa agataatgtt aggtatatta ctttatgttt ataaggcttc ttttaaaaat
    41641 tttaaaataa gtaaaaaaga gatatacata tgtattccta tgatagcaaa tttattgtca
    41701 ttttttgtac tttatgatta tattattaat cttgtaaaaa tctctcctga aagaagaact
    41761 gcttttttag taatagtttt actattaata ttatctaa
//
LOCUS       DAEPHU010000030        41510 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 01A10CD0081
            SAMN05941466-rid12468953.denovo.030, whole genome shotgun sequence.
ACCESSION   DAEPHU010000030 DAEPHU010000000
VERSION     DAEPHU010000030.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941466
            Sequence Read Archive: SRR6291087
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 41510)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 41510)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068158.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 22:43:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,892
            CDSs (total)                      :: 3,805
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 87
            rRNAs                             :: 8, 1, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 55
            CDSs (without protein)            :: 55
            Pseudo Genes (ambiguous residues) :: 0 of 55
            Pseudo Genes (frameshifted)       :: 21 of 55
            Pseudo Genes (incomplete)         :: 28 of 55
            Pseudo Genes (internal stop)      :: 16 of 55
            Pseudo Genes (multiple problems)  :: 8 of 55
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..41510
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941466-rid12468953.denovo.030"
                     /strain="01A10CD0081"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            37..1914
                     /locus_tag="KR231_001712"
     CDS             37..1914
                     /locus_tag="KR231_001712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HBH0004091.1"
                     /translation="MNIPIVVNEKSKDIIKDWQYTCTNEDIKFTSIIILTYNQIEYTK
                     LCIESIRKFTPKNKYEIIIIDNNSSDGTVEWLKGQSDIKSVYNNKNLGFPKGCNQGIE
                     LATGENILLLNNDVIVTPNWLYNLNKALWSQDNIGAVGPITNACSYYQQIDVDYKSIE
                     DMFIFAHKINKSNINLWKYRLKLVGFCMLIKKTVLDNVGVLDELFTPGNFEDDDLSFR
                     MIESGYKLLLCQDTFIHHFGSVSFKENRNKYTDIMYINRRKFETKWGFNPEYSGMIRT
                     DLISKIDDSLEANINVLEIGCGIGATLLEIKNIYKNASIYGIEISESAGKLAKYSADV
                     LIANIEKVKLDYKKDFFDYIILGDVLEHLIDPWKIVNELKQYLKKDGYLVSSIPNIMH
                     VSVLRNLVLGNFTYEDSGILDKTHLRFFTLNEITKMFNDSNYIINSITATSMPLSEID
                     NSFIDTICKESCKEMRQQYESYQYIVKASKILDTKRYSSISMINLKYALMRIDNELDV
                     DSNLSYIFDNYNITEPCFVDDIEYLIDTFVINKATLLNRLGVEAFNRGLGDFSINMFM
                     TVLEMDRDDIDSIYNITSVLCELEEFDTAYNLIKNSSEKVQSESDIQEILCFIEGKKY
                     E"
     gene            1907..4021
                     /locus_tag="KR231_001713"
     CDS             1907..4021
                     /locus_tag="KR231_001713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase"
                     /protein_id="HBH0004092.1"
                     /translation="MNNDKICFITCVNDERLYEECLVYINSLDIPKNFSIETVALRGA
                     DSIASAYNKAMRETDSKYKVYLHQDTFIINKNFIHDILEIFKKNTDVGMIGVAGVKDM
                     PVNGIWWDSDKKAGKVYDSHTGKMDIYEFSNFEECFNEVMAIDGLIMITQYDVFWRED
                     KFDGWHFYDLSQSMEFRQNKYKVIVPKQNKPWCMHDSGVVNINNGYDEYRIKFVKEYI
                     NLDLYRENFYEFDKKKASTILKSNKHVMDCMKEELTEQLRLKNYKDVLGIVSKIAHFS
                     VFNHTGLYSCEECERALLECANNLPEIENTKLFTKKDLKRRKVLHVLSEGYSTGGHTR
                     LVKNWIEIDKDSVHSVVTTWQSDTLPDWLLKAINDSGGEVISLDLISDDYLKRAVALR
                     KIAYDWADIVILYVHMWDTIPVVAFGVDGKIPILHVNHYDSTFWLGTSIADIVIDFSE
                     TSQLITLDKRGIDKSEILPMPLKEKEVFSKSEVRKRYNLEDDVTIILTIASERKYNSV
                     NDINYFKIAKTLIENTDNTIIIVVGVDTENLYWKTLSNVTDNRVICFGTTANIDDFYK
                     ISDIYLESFMVGSHTSKLDAILYDLIPVKFKNEVSPIFTNMWNFIDKFDYKNIKEVID
                     MIRRYNTSEFDRDKIKAKQSEIKHFVIDKHCIEIKNYIDKIYNEVNHHKVKYDLYKND
                     EIEDYQLFVALYGYMVKNKNMS"
     gene            4030..5025
                     /locus_tag="KR231_001714"
     CDS             4030..5025
                     /locus_tag="KR231_001714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan bridge formation glycyltransferase
                     FemA/FemB family protein"
                     /protein_id="HBH0004093.1"
                     /translation="MNNIHINKFEKSCEKNWDYFVENKSINGTFLQTRNFLNYHEEGK
                     FTDHSLIICKGEEILAVVPACETYEDGERIFFSHLGSTFGGIIIRSGFNDIRHVNAIT
                     NKLEIYLQEQNFDKVYLKNTSRIFCKEDTSLLEYFLFKNNYMFYDELSMFLELSKYKE
                     DILANFKYSKRRDFKYSLKNNLTFKRLYSDEDIVCFFNLLSNCLDSKGAKVIHSVEEL
                     LEFKNNRLKDIVEFYAVYIDDIMICGSMVFNFQERVYHTQYLASNSTYNKYYPMIFLY
                     YNLIKDALERNFKYLSFGISTLNRGKYLDEGLATFKEGFGSSAICNRTYYKNINK"
     gene            5117..6349
                     /locus_tag="KR231_001715"
     CDS             5117..6349
                     /locus_tag="KR231_001715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-grasp domain-containing protein"
                     /protein_id="HBH0004094.1"
                     /translation="MKRLMILGSIKYFENIVMSAKREGIYTIVCDNRIDTPAKKICDE
                     AIDVDVFDFDKIKNIAIDKKIDGILTGFTDSLMKPYVYIANELNLPCVISCNQLESVT
                     NKAVMKNYFKNNGIPTTDYCIIESLKDLEKIQGLNFPLVIKPVDGYGSRGVYFVSNIE
                     ELIEKFEYSKEASQDGQVIIEEFYESEEIQGLAWVHNGESHVFYIGDRELVNIHTGRA
                     GKPDRLIYPSKYCFQYEEEIKSIYQNITQAFGIKNGPLYVQMLVGAYGIKVSEVMPRL
                     PGGCDYMAISQITDLDIGSLFANFSVNNEVNFDEIKKYNMHLSKCVYALPIYIRPGTI
                     KKINNIDKIENLDYVTQFLLLVKEGDTIGLYEDERQDCGRVYGVANNVFDANIKKKCI
                     HEMIEILDENNENMIENF"
     gene            6369..7313
                     /locus_tag="KR231_001716"
     CDS             6369..7313
                     /locus_tag="KR231_001716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine cyclodeaminase"
                     /protein_id="HBH0004095.1"
                     /translation="MKLITHEQIMSLNISQKQGYEWIKESFLTKKDCQLPPKISMVEE
                     GHVFYNVMPSLNHNHKIGGIKMVTRLPGRNPSLNSEIFLYNMEDAKLKAILDGNYITA
                     FRTAAVAALAIDTFAKKDFNTIAIMGLGVTASAIMNMLSYTLKDKNINIKLLKYKDQA
                     ESFVKKYEKNEQFSFEICDTHEELIVDSDVVISTVTYTDEYLSEFKWFKKGALLLPVH
                     VMGFGNVDYLFDKVYLDDYNHLKHLENIDRYKYSCEFYDVLSKQAKGRENDDERIISY
                     NIGLSIHDILFANKIYELCETLSCEEIELKEPKEKYWI"
     gene            7407..7814
                     /locus_tag="KR231_001717"
     CDS             7407..7814
                     /locus_tag="KR231_001717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WxcM-like domain-containing protein"
                     /protein_id="HBH0004096.1"
                     /translation="MDKYNLIRFVSIGNEYIGNLVALESNKAIPFDIKRVYYIYDVPN
                     NVKRGFHAHKNLEQVLVCLNGSVKIKCYDGVKETIFNLHKNDVGLYIGTGVWHEMFDF
                     DEKTVLISIASEHYNEEDYIRDYKEFLKYLNNV"
     gene            7901..8992
                     /locus_tag="KR231_001718"
     CDS             7901..8992
                     /locus_tag="KR231_001718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegT/DnrJ/EryC1/StrS family aminotransferase"
                     /protein_id="HBH0004097.1"
                     /translation="MLVKFNNLLKQFQTHKEEYEQKIKDVMESGYYILGNEVKHFEEE
                     FANYVGSKYCVGLASGLDALIIAFRALGISKGDEVIVQSNTYIASVMGISINGATPVF
                     VEPNEYYNIDSSKIEEKINSKTKAILVVHLYGQASNMKDIQELCDKYNLYLIEDCAQS
                     HGAKYDGKMTGTFGDIGCFSFYPSKNLGAFGDAGAIVTSNEEIADKVKILRNYGSEKR
                     YYNKFVGYNSRLDEIQAGLLRVKLKYLNEIEIEKSKIVDRYLNEINNPKVILPKIENN
                     CTHVWHLFVLQVEKRDTFMEYLKKSGIESIIHYPIPPHLSEAYAYLGYKKGSFNIAEN
                     YSDKVVSIPLFIGMEDEEVSYIIKIINEY"
     regulatory      9301..9391
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01051"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="cyclic di-GMP riboswitch class I; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="cyclic di-GMP"
                     /db_xref="RFAM:RF01051"
     gene            9799..10116
                     /gene="flgB"
                     /locus_tag="KR231_001719"
     CDS             9799..10116
                     /gene="flgB"
                     /locus_tag="KR231_001719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar basal body rod protein FlgB"
                     /protein_id="HBH0004098.1"
                     /translation="MNTYDIIKMGLDATNLRSQTIANNIANINTEGYKRHYITFEETL
                     NDAMPKIEEKTDNSKGLRVDGNNVDIEEEKVNQAMATLQYNALISFANGKIAMTKSII
                     SGR"
     gene            10124..10528
                     /gene="flgC"
                     /locus_tag="KR231_001720"
     CDS             10124..10528
                     /gene="flgC"
                     /locus_tag="KR231_001720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar basal body rod protein FlgC"
                     /protein_id="HBH0004099.1"
                     /translation="MSVFSGMRISASGLTAESLKMDIISSNVANINATRGPNGEAYRR
                     KVVSFEENYDNKLGMLGVKVTSVEDDKSPLKEVYDPSHPDAKPNGYVEYPNVNILVEM
                     TDLITASRAYDSNVDTLNAQKSMISKALEIGK"
     gene            10538..10855
                     /gene="fliE"
                     /locus_tag="KR231_001721"
     CDS             10538..10855
                     /gene="fliE"
                     /locus_tag="KR231_001721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar hook-basal body complex protein FliE"
                     /protein_id="HBH0004100.1"
                     /translation="MPITQINNLMQGAKLDNLIGEAKPLTLNNKEEKKNFEDVIIDTI
                     DKVNFQQVTADDMKEKFIKGEDVSMHEVMLIGQEAQLSMQYLIEVRNKIHDAYQEMNK
                     VQI"
     gene            10880..12430
                     /gene="fliF"
                     /locus_tag="KR231_001722"
     CDS             10880..12430
                     /gene="fliF"
                     /locus_tag="KR231_001722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar M-ring protein FliF"
                     /protein_id="HBH0004101.1"
                     /translation="MITSFKNKIKEQVAKSRTKISSLKKGTKIALGIGVIAICLALVF
                     TAISASKNKYAVLFSELDAQDAADISAELESKKIDTKVKGSTIYVPRTEVDKLRLELA
                     PSLTGGSKGFALMDDSSSIGLTDEEFQIKKQRMIQGEIEKTIKSFPQVEDTRVHITFG
                     ESSVFEKEAVPGSAAVYLMLKPGTTLEKNQIKSVMALISGSVTNIPEKNVQVIDNKMN
                     LLSEGILEDENVDENNQPINSGISVDKNKASEQALNKQLEKSILEMLEPIFGKGKVKA
                     TVNADLSFDTAEKTEIKIDPDKVAIKETRSKNSSKSAANNVQGVDANMNNQGNNNGTN
                     TEDSLDESFEYETGKIETHTIVAPGELNRLTASVAIDGKIAKGVQADVEDIVNNAIGM
                     DGARGDTLSVVSMVFDPEGKKEAKQELEEIKKEGFKKNIIKAVIGVVAVIAVGAIGYL
                     IYKKRSEREDMDYEDEDYISKSDSVDRKDNPLLGDDPELTLEEAVKMYAEEKPDQVTE
                     IIKTWLNE"
     gene            12443..13513
                     /gene="fliG"
                     /locus_tag="KR231_001723"
     CDS             12443..13513
                     /gene="fliG"
                     /locus_tag="KR231_001723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar motor switch protein FliG"
                     /protein_id="HBH0004102.1"
                     /translation="MSTEITNVNAFDLSDINESDKNEKVEGEGLKKAAVLLMTLGPNV
                     SSDIIKSLPDKQVQKIGLEIANISSIASKERREILKEFVEINRAKDYVIEGGLEYARE
                     LLSNALGNVKANKLLEGISINTSTKPFKHIIKLDVKKILEILRNESAQTIAVLLAHME
                     PENGAEVLSYLDFDLQNEVAMRISSMGSISPEVIKVIESSLEDKLHSISGDDFNDYGG
                     VSTLVQILINSDRKTEKNILGTIEEQNPDLAAQIKSHIFVFEDIVKLDDISIQKVLKE
                     VTMKDLVYALKGVDDEISDAIYRNQSSRAADALKEEMEMVGVIKVTQVEASQQKIANI
                     VRKLEREGAITIVRNFGGDFVE"
     gene            13506..14237
                     /locus_tag="KR231_001724"
     CDS             13506..14237
                     /locus_tag="KR231_001724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar assembly protein FliH"
                     /protein_id="HBH0004103.1"
                     /translation="MNNKIIKSKKALYKGVLDLTIIDKVRVGESNVNKENDCRFRDEV
                     IKEAIESAEIKKNEILEEAKINAQNIEKQAYEKGYSQGQKNGYEDGYKESYDEYTQKA
                     KDEADFIKNQANLILLQANEKMTEYIKEKNKEIVRLAINMASSVLKKHFEDEESMSDL
                     LKQIIQDYEGSSSFIVRCNSFYKDNIEKEFELFKEETSLKSSVFVIADDSIDKGNAII
                     QKENGRIIVGIDCAMEKLKEELLGE"
     gene            14241..15560
                     /gene="fliI"
                     /locus_tag="KR231_001725"
     CDS             14241..15560
                     /gene="fliI"
                     /locus_tag="KR231_001725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar protein export ATPase FliI"
                     /protein_id="HBH0004104.1"
                     /translation="MYKTDISIDFDKINKKIENLELTISEGRVKKIIGLTVEVEGIKA
                     FVGELCVIYNQVNKPVNCEVVGFKDKEVILMALGELTLIAPGCKVISKGIPLSVMCSD
                     NLLGKVLDGLGNPIDNSDAVLGDRYNLNNEPPDPMKRKKIRNIMETGVRAIDAFTTCG
                     EGQRIGIFAGSGVGKSTTLGMIARNAKADVNVIALIGERGREVLDFIDKDLGEEGMKK
                     SVVVCATSDKAPLVRLKGALTATAIAEYFRDQGKKVILMMDSVTRFAMAQREVGVAIG
                     EPPAQKGYTPSVFAMLPKLMERTGTSDKGSITAFYTVLVDGDDFNEPIADTTRGILDG
                     HIVLSRDLANKNHYPSIDVLNSLSRLMNEIASKEDIKIASFARDMLAEYREAEDLINI
                     GAYASGTNKKIDEAIYYHEHIINFLKQGINEKSSFNETISSLRRVFE"
     gene            15591..16037
                     /gene="fliJ"
                     /locus_tag="KR231_001726"
     CDS             15591..16037
                     /gene="fliJ"
                     /locus_tag="KR231_001726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012815984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar export protein FliJ"
                     /protein_id="HBH0004105.1"
                     /translation="MELDKNFKFRLQKVLDLKVKDEEEIKMEFAKIQQKKIDIETNLE
                     NLESNYSKYSISKNNDSIQNQKITINYLLALNNSIMDLSEELDKSTNELEKARKQLIS
                     KQIERKSLEKLKEKKYGQYYKEENLKEQNTNDEFASMSYLRNRQVL"
     gene            16066..17271
                     /locus_tag="KR231_001727"
     CDS             16066..17271
                     /locus_tag="KR231_001727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435997.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar hook-length control protein FliK"
                     /protein_id="HBH0004106.1"
                     /translation="MKIQADSYNIIKDIGDRKSSSKNKNIKNNKFEDNLYKATDHKKV
                     KDRREVSKQNISSDKPENSDNECHLDEDKSNHLEDENTYEKDCSKNNEALQQLLNLLK
                     DNYKKDKDINTILNNIEKLSISDELKQELKLNKNILNKIANQNSELNKANINNSNDIE
                     NLDIVKLRELLEDNANKDIEVITKTTENDTKNIDLYSFDSNRMDNLNSNKQKDDSSDI
                     LEKLAGVNGNKSGNFGQVINKNVDMNKIKNDNVNLKQIESNVMDDSIKAIKHMKTNDI
                     QELTIKLRPKELGDMNIQLLKDGESMRAVVTVFNKDVFDSINKNIADLKQHLELTNVN
                     IKDVSVQMHSDNTNTSDTFDKAFEQQNRQNNQENMSKKNTNDKHNNVVIEDDIKENTI
                     DDDRVDLLA"
     gene            17289..17897
                     /locus_tag="KR231_001728"
     CDS             17289..17897
                     /locus_tag="KR231_001728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar biosynthesis protein FlgD"
                     /protein_id="HBH0004107.1"
                     /translation="MYGIATALAGTQGNYRSNNLSQLERNINDIANKQVRSKGNQTVT
                     DNGTPIIGQGDDADKDLFMKILVAQMGNQDPMNPQDPTEYVSQLAQFATLEKMSAMNE
                     KLDVLLALSNSTLINSALSMATSLIGKEVEVSGEEKEDENIVGVVKSTYIKDGEVHLE
                     LEVDGSDKTVGVKYEKLLKIGEVDENSGEENDSSEHESPEEA"
     gene            17924..18907
                     /locus_tag="KR231_001729"
     CDS             17924..18907
                     /locus_tag="KR231_001729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar hook-basal body complex protein"
                     /protein_id="HBH0004108.1"
                     /translation="MIKAMYSGVSGMKANQTKLDVIGNNVANAGTTSFKKSSARITDS
                     FYQTVLYASAPTAALGGTNLGQVGVGSKISSINKDMVQGNVQPTNRPSDLMIDGDGYL
                     PVVRQGTVMYTRDGSFNLDTGFKAADGALKNIKGGRLVNGDGYMLQGMIYDGEYKADT
                     GEFVKKGDAKGKEPIVIPLQSISPKDGTVQNVLEYNISKDGTVEFLLSDGQRTQFVYD
                     IPDGAKVGDTPAGIDKLKGTIQKVQTYAFQNPAGLDAEGGNLFKPSANSGDPQIAGAT
                     GTIIQGAIEASNVDIAEEFTEMIIASRSFQANSKIISTSDEILQEIINLKR"
     gene            18920..19123
                     /locus_tag="KR231_001730"
     CDS             18920..19123
                     /locus_tag="KR231_001730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar FlbD family protein"
                     /protein_id="HBH0004109.1"
                     /translation="MIRVTDLNGRKYILNSDLIVRIDSVPESRILLTTGEKNLVKESV
                     DEIVDKVIKYKRKINVGYIRSEK"
     gene            19123..19941
                     /locus_tag="KR231_001731"
     CDS             19123..19941
                     /locus_tag="KR231_001731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MotA/TolQ/ExbB proton channel family protein"
                     /protein_id="HBH0004110.1"
                     /translation="MKKTDSLTFIGLIVSTVLVLVGAAKGSSSGLKNFFDVSSILITV
                     LGSFGALMITFTIDDIKLIKNALQYSFKTMSVSKLDLLEQFKTLSKKARKEGLLSIES
                     DVMGIEDPFMKKGLELCIDGLEINEIRSILELEIDSVEDTNNRYSKLFKTWGTFAPAF
                     GMLGTLIGLIQMLADLTSPDLIASGMGKALITTFYGSLLANIALNPIAYNIDEKTEKE
                     IYVKEMMLEGIISIQSGESSIVVEERLATYLSNNEKLEIMKSNKNTERAMSNGA"
     gene            19931..20626
                     /locus_tag="KR231_001732"
     CDS             19931..20626
                     /locus_tag="KR231_001732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425218.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="OmpA family protein"
                     /protein_id="HBH0004111.1"
                     /translation="MARKKNKKKDEINPDAWLATYADTITLILTFFVLLYATSVVDME
                     KFKNIADALKGQFSGTSIFSTGSSTSEKSPIDSVLVDKNDKSNLEQDLKDKVNNSNLQ
                     NSVTVKDDSRGILLELDDSILFDSGISELKVDSKATLNKVYDMIKMMKNKIVIEGHTD
                     NVPVKSSTHESNWDLSSSRAVSVVRYFVEEKGMDPRLFSATGCGEYQPLVSNETAKGR
                     AENRRVNILITID"
     gene            20638..21081
                     /locus_tag="KR231_001733"
     CDS             20638..21081
                     /locus_tag="KR231_001733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar basal body-associated FliL family
                     protein"
                     /protein_id="HBH0004112.1"
                     /translation="MFKNKKIIIIILILIIFSAGAGFFILGEGGNKQVDKIADLFIPT
                     GKGKDEVKTENLDLEEMVLKLADEGVRYLKVSITVSYDSSYKDIEKNTPLIRDNIINC
                     FMAKRADDFTADNLKNIKEEIKNTLNIQLGENVIQNIYFTNIVVQ"
     gene            21096..21470
                     /locus_tag="KR231_001734"
     CDS             21096..21470
                     /locus_tag="KR231_001734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar biosynthesis protein FliZ"
                     /protein_id="HBH0004113.1"
                     /translation="MILYLLKILICIPIILILIVLSLKISQGTLLKKYNDKYVKILDI
                     VNISKNNSIIILKIGEEGCIMASSSSSMSKIKDLTKEEILKIENDIKERNFKIQDFKM
                     ERIKKKYDFSRYIGKFTKKEDK"
     gene            21471..22136
                     /gene="fliP"
                     /locus_tag="KR231_001735"
     CDS             21471..22136
                     /gene="fliP"
                     /locus_tag="KR231_001735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425215.1"
                     /note="The bacterial flagellar biogenesis protein FliP
                     forms a type III secretion system (T3SS)-type pore
                     required for flagellar assembly; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar type III secretion system pore protein
                     FliP"
                     /protein_id="HBH0004114.1"
                     /translation="MELLSKLPLADVPYTSSMQLFLFLTALMFLPFVMFMMTSFVRIV
                     ISLSFLKSALGAQQAIPSQILVGLAIVLTIFIMRPVLNEINEKALQPYMKEEVTMEEA
                     MKEAEGPIKEFLLTQTRQTDLDLFVEQAGLKEKKLTRENIPLSVVVPAFAISELKTAF
                     QIGFLIYIPFLIIDLVVASVLMSMGMFMLPPVMISLPFKLLLFVMVDGWNLIVKTLIL
                     GFG"
     gene            22149..22418
                     /gene="fliQ"
                     /locus_tag="KR231_001736"
     CDS             22149..22418
                     /gene="fliQ"
                     /locus_tag="KR231_001736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar biosynthesis protein FliQ"
                     /protein_id="HBH0004115.1"
                     /translation="MSEFMIMSVLKNGMFTGAMIAAPVLIVSLVVGLLISVFQATTQI
                     QEQTLTFVPKLIAILLVVAIGGSWMLHTLISFTSEIFNMISLITK"
     gene            22430..24244
                     /locus_tag="KR231_001737"
     CDS             22430..24244
                     /locus_tag="KR231_001737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fused FliR family export protein/FlhB family
                     type III secretion system protein"
                     /protein_id="HBH0004116.1"
                     /translation="MIFVFIRIVAFFGTLRILFPAGTPALFKSLFAIIISILISSTMQ
                     IEYATNIDNIVLFTLYGVNETITGIMLGYITNLCFYSIRMAGSMMDQQMGLSMINMFD
                     PNSMTQTTLIDNLMNWTALMIFFSMDGHHVLIRGIRYSFELIPIGKPFVDNNIDYIIN
                     IFVQCFLTGFKIAIPIVLCLLMADFILGLISRSVPQLNVMIVGMPLKILVGIALFIIS
                     IPLIVNQISHLLSQIPKMYEGTFALAPMFFMGSADKTEEATPKKKGEQRKKGNIAKSR
                     ELPVAMTLLAFTLLVPTLFSYVVDTLKSSLNYFLSLDFYMNINYSNLEKLVIAGLMDF
                     FKIFLPIAIPFLVLGIIANLFQVGILFTGETLKPNLSKLNPISGFKNMFSMRSLSTLI
                     KDTAIISILAYIGYTFFQDNYLDILKLGNIYLPTLMYTVKDLVYSILSKICVAMIAIA
                     VADYVYQRYSHKKQLRMTKQEVKDEYKNSEGDPEVKAKIKQKQRQISSQRTMQAVPSA
                     TVIVTNPTHLSIAVRYEKGKDQAPVVVAKGADYLAFKIREIAKGNNIPIIENKPIARL
                     LYKQVEIDQEIPEDMYQAFAEILVAVYKIKNRYKVPKR"
     gene            24253..26328
                     /gene="flhA"
                     /locus_tag="KR231_001738"
     CDS             24253..26328
                     /gene="flhA"
                     /locus_tag="KR231_001738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar biosynthesis protein FlhA"
                     /protein_id="HBH0004117.1"
                     /translation="MNKFNLKENMDVIVAFGVVGIVLMMIVPLPTFILDILLAINISL
                     SVLILLMTLFTTNVLDLSIFPTVLLVTTLFRLGLNLSSTRLILTQGYAGEVIEAFGSF
                     VVGGNYVVGIIIFLIILIVQFVVITNGSGRVSEVTARFTLDAMPGKQMSIDADLNAGV
                     IDDKTARKRRKELQQEADFYGSMDGANKFVKGDAIAGLIVTAINIIGGIVIGAVMLNM
                     TLMGAAQTYVRLTIGDGLVSQIPALLISTSAGIIVTRASTDENFGDLVGKQLTAIPKA
                     VMMTGCVLIVLGMMPGLPKPAFFSLGIGAIAAGYFLGREKKDTLEDLEFEKPDMVNPD
                     KNEVEDVTNLINVESIEVEIGYGLISLADESAGGDLLQRIASIRRQCAIDMGIVVQPI
                     RIRDNLQLNPNQYNIKIKGNVVGGYEIMPNMVLCMDPMNQGFSIFGIKTIEPTFGIEA
                     LWIESDKVEDAELKGYTVVDSSTILITHLLDIIKSNAHELLGRQEVKTIIDAARENYS
                     AVVDELIPDLMTLGEIQKVLKNLLREKVNIKDRVTILETLADQSRNTKDIELLTEYVR
                     IALARSICNNLVDDDKTIVVATLSPETEELVSNNLQRSVNGTYPAVDPENTNKIFESI
                     QEVMSNVYFNHNIPVIVVSPKIRAPFRKLVEIVYPNLTVLSLNEIPNDIKIKAEGVVS
                     IYDDEKVYS"
     gene            26303..27319
                     /gene="flhF"
                     /locus_tag="KR231_001739"
     CDS             26303..27319
                     /gene="flhF"
                     /locus_tag="KR231_001739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar biosynthesis protein FlhF"
                     /protein_id="HBH0004118.1"
                     /translation="MMTKKYTANTIQDAMNLAKMELGDNITLIDKKEVRKSGIQGIFS
                     KKDIELTIGWEKRENVEQKDLKREIEQLKSIINNMGFDNKNDNDIDKICKNLLSLELN
                     EEIVESIRIDLQEMKFNGIDTSKNLVEILKKKIKIENQVINGKIALVGPPGVGKTTTI
                     AKLAAKLVFEENKKVGVITIDTYRIGAVEQLKIYTDIMNIPFKGVISPDEMELALDEM
                     KDCDVVLIDTTGRGYKNSMQILEIKNLIDKAETDNIHLVLNCTTRESDTKAIIDSYRN
                     VNFKSLIITKLDETITYGSIFNIMNYAQKPISYITTGQNVPDDIIKPNEDKIIRLLLG
                     VESI"
     gene            27316..28194
                     /locus_tag="KR231_001740"
     CDS             27316..28194
                     /locus_tag="KR231_001740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MinD/ParA family protein"
                     /protein_id="HBH0004119.1"
                     /translation="MIDQAQILRKIAMEKRGLDEFIVENENVPKIITIASGKGGVGKS
                     NLATNLSICLTKLNKKVLILDADIGMSNIDIIMGVNVKGTIIDVINGEKNIEDIISQT
                     KYGVNIISGGSALNHIEDFTEAQRNKFIHSIEQIHDVDFIIIDTGAGMSKSLLSFIYC
                     STEFFLITTPEPTSLTDAYSLLKAISNFGIKRSANIIINRVIDLEEAKSTYKRIKMVV
                     DKFLNLNLELYGYIIDDKKVSLCVKKQIPFILEYPTSIASKCIIAIAKRMVSQSREDI
                     VDNKSFLRKMFSIFKS"
     gene            28208..28909
                     /locus_tag="KR231_001741"
     CDS             28208..28909
                     /locus_tag="KR231_001741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FliA/WhiG family RNA polymerase sigma factor"
                     /protein_id="HBH0004120.1"
                     /translation="MNREELIKENMPLVKSIARKFFIPGKGFEYQDLVNSGVIGLIDA
                     INKFDAEKGAKFSSYSYIKIKSAILDEIRNQSPISKHNLTKVNKYNRVVEKLQSKLLR
                     EPTSYEIAKELKVSEKELHDIESNIDMLNIVSLNYVIFEDTNETVQDVISDREEEAPE
                     NIIEEEEKLEILSKAISNLNEREKLILSLYYYEDLNLKEIGKVLGVSESRVSQLHRKS
                     IRNLRNKIKELKYSI"
     gene            28925..29347
                     /locus_tag="KR231_001742"
     CDS             28925..29347
                     /locus_tag="KR231_001742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar protein"
                     /protein_id="HBH0004121.1"
                     /translation="MIQIILIVVSILIIVTIVINLHKESKNKDNRYFDKIFEQEYEAN
                     DRLIIAEKRRFFLDKVLAEKRINSHIKVYENYNLIKANEERKENIFIESKKEVRQENE
                     LSLKVKHLISSGYDDVEICKMLDIGKGELLLIRSCYKI"
     gene            29332..29517
                     /locus_tag="KR231_001743"
     CDS             29332..29517
                     /locus_tag="KR231_001743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar protein"
                     /protein_id="HBH0004122.1"
                     /translation="MLQNIRILLCDKKVFLGIGIGILISTLCIMLFSNNDMSKAEIEK
                     KARALGMKYTSEMKVLE"
     gene            29558..30331
                     /gene="flgG"
                     /locus_tag="KR231_001744"
     CDS             29558..30331
                     /gene="flgG"
                     /locus_tag="KR231_001744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar basal body rod protein FlgG"
                     /protein_id="HBH0004123.1"
                     /translation="MIRGLYTAVSAMITNQQKQNVVVNNLANMDTNGYKSKQLLTKSF
                     DELKLEGYNNYANGTKQKQIIGDISPGISMDETITNFNQGPIKTTDNKMDVAIQGKGF
                     FLVSDAAGNQFYTRNGNFRTDNQGDLITSEGYYVLGTNTATGAVGHINVGNQKFEVAK
                     DNTISLDGNAMYKFNIVDFNNYNNLKKEGDNLYSGGGAMKVNNALTIQSAIESSNVDM
                     VSEINNMMTISREYEANQKIIQAMDSKLAKIASEIGSVR"
     gene            30352..31113
                     /gene="flgG"
                     /locus_tag="KR231_001745"
     CDS             30352..31113
                     /gene="flgG"
                     /locus_tag="KR231_001745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar basal body rod protein FlgG"
                     /protein_id="HBH0004124.1"
                     /translation="MYTMFYTSKTALSANQSKLDIISNNIANSDSTGYKKINMEYSDL
                     VDEVLNRPSYPTNGNDISTGTGAKATAPMRNYEQGALAPTDSKSNLAIDGEGFFRVIR
                     KDGTYAYTRNGGFNVDALGKIVDDNGNILDVQFDAGYNYNNTNIDSTNLTVSRNGELF
                     VDNKKIGKINLYQPIGTQNFISEGDSLFVATDAAQIKQVEKVDIVQGYRERSNVSLQE
                     EFVDLIATQRAFQMNSKGIKTADEMWQIANNLRAK"
     gene            31136..32017
                     /locus_tag="KR231_001746"
     CDS             31136..32017
                     /locus_tag="KR231_001746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FliM/FliN family flagellar motor switch protein"
                     /protein_id="HBH0004125.1"
                     /translation="MNDMKEYDFGKPQSYSRENLTCLNFLLAEFCKKYKNYIIYELKC
                     NSSMVVDSIDQVNYQTFLDRVTSSCVVVQNAMEPVMKNFSFRIDRSVADMWIDITSGG
                     TGVVKDNDRELTELDKKVLLHLMDDLVRNMHLFEGFENIQVLDTHTHINLPQLCSPTA
                     PVCVVDLKVLNDNEYIGSVSLCFPYNGLEALLESISVIEFFDNDVGDDSEEFTQKIYN
                     SVSNIELSVIAEIGKVSINVEDLLKLEVGDVIVTNKKINDYIDIFVENSKSYTATPGF
                     ISSKKGVKINDAVGKEV"
     gene            32020..32394
                     /locus_tag="KR231_001747"
     CDS             32020..32394
                     /locus_tag="KR231_001747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FliM/FliN family flagellar motor switch protein"
                     /protein_id="HBH0004126.1"
                     /translation="MDNSNLISDEEAKMLLNDKVESEVDGDDELALDVSEVNRNNIQR
                     ILDLKLELSVVIGRTKMTLRDILNLHKGSLIELDTLADQDVEILIDNKVLAYGKVVVV
                     DLNFGVKITSIVSEEDMVKSLV"
     gene            32426..33829
                     /locus_tag="KR231_001748"
     CDS             32426..33829
                     /locus_tag="KR231_001748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0004127.1"
                     /translation="MVLILNLNDIKKDILKLNKKDSCSLYNESINNINNNCISTGLKF
                     LKQARDLNPDDVDILNLTGLVNLLKCNFDDAVESFYKSSLCEKTALCEKYINMLTSEE
                     FLIFFEKYNQLIRLINKGMYKEAIQGFKLITDQYCDLIEPYELLALLYDKEEEYIKFD
                     ECLEVLKIIDKENYLLNQENNTLYMYNSANIQTKSNIKVDDYKNEFLHKSSSNHKIND
                     YNDVTKEKSSSKNQKSSDSNKKKSIKKNKYLYIAIILGILLVGQSIYSSYKMNNLTDK
                     ISKNNETKNEESIDSNLTKKENNIEENEDMSKASNINKSNKNINKEDDVKSKKNTVEN
                     EDDKDSDLFTEDELMSKANTLKSEKKTKSSIQLYKKVADIGENKGNTSEATYQVAILS
                     EKLKDYKTAEEYYKMYVENYSEKDAYFDESYYNLSMMYYNNGDLKNSKLTLKKLVNKV
                     PNSMYNNSKVKEILKEE"
     gene            33945..35882
                     /gene="htpG"
                     /locus_tag="KR231_001749"
     CDS             33945..35882
                     /gene="htpG"
                     /locus_tag="KR231_001749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435963.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone HtpG"
                     /protein_id="HBH0004128.1"
                     /translation="MEFEKGSISIHTENIFPIIKKWLYSDKDIFIRELISNGCDAVSK
                     HKRLVSLGEISENKSSDYKITVSVNKGEGTLKFIDNGIGMTEEEIKKYINQVAFSGAE
                     DFFNKYKDKMEESNDIIGHFGLGFYSAFMVSKKVQIDTLSYTEGATPVRWISEGGTEY
                     EISESDARNDRGTTITLFIDDDSKEFLDEFTVRGIINKYCSFLPVEIYLEDVERLERE
                     AKEAEEKAKKQKEDGKEEIVDAKVIEPLNDTNPLWLKSPKDCTDEEYKEFYRKVFNVF
                     DEPLFWIHLNVDYPFNLKGILYFPKLKNEFELTEGKVKLYNNQVFVADNIKEVIPEFL
                     LLLKGVIDCPDLPLNVSRSFLQNDRDVSKISKHIIKKVADKLKSLCKNEREEYNKFWD
                     DIQIFIKYGCLKDESFYEKVKECILFKTIDDEYITLQDYLEKCKDKHENKVFYVSDKE
                     QQSQYIKLFKEYDLSAVVLNSSIDTHFISFMEYKENGVKFNRIDADLSDVLKDKNENK
                     DSEENKEEIAKIEGLFKEAVGERVKNYSVEGLKNEDTPAMVLVSEQSIRMAEMQSRFA
                     GMDLGMNFEEEKTLVINENSPIIKKLVSLKDDEEKKDKITLICNQIADLALLSNKELK
                     PDELDSFVQRSNKLMSLLIEL"
     gene            36269..37399
                     /locus_tag="KR231_001750"
     CDS             36269..37399
                     /locus_tag="KR231_001750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase"
                     /protein_id="HBH0004129.1"
                     /translation="MNFNYNLPVNILFGRGRINDVGKEVSKYGKKVLIVTGKNSTKKT
                     GLLDKTIDLLKDSKIEYEVFDRVEQNPLITTIYSGVEIIKSTGCDCVLGLGGGSIMDA
                     AKSIAFSYKNPGDLNDYIFGIRQGEEALPIILVPTTSGTGSEGNCFAVLTNSETKDKK
                     SIKKNSMYAKASIIDPELMVTMPKHIIASVGFDALAHNMEAYLSNGRNPLADVQAIYG
                     IELISENLIKVYNDVNDLEAWEKITLASTIGGMTIGTAGTALPHGMEHPVSGLRDVMH
                     GKGLAALTPTIIESSWDSDIERFGNISKVLGGTCAEDCSDAIRNFLKKIDLDIKLSDL
                     GIEKSDIDWLTDNCMKISVANIKRHPKYFNKEQIKEMYHKSL"
     gene            37626..38648
                     /gene="splB"
                     /locus_tag="KR231_001751"
     CDS             37626..38648
                     /gene="splB"
                     /locus_tag="KR231_001751"
                     /EC_number="4.1.99.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="spore photoproduct lyase"
                     /protein_id="HBH0004130.1"
                     /translation="MFNPKRIIFEKGTLDTDVGKKIYNKFRDNKDVEIINISSNRIKE
                     HIPGENLYEQYRSGKQTMVVGIRKSLKFQTCKPSANYQLPLVSGCMGRCEYCYLNTQL
                     GDKPFIRVFVNVDEILEQTKKYIEDRKPQVTIFEGAATSDPVPVEPYTNSLKKTIEFF
                     GREEKGRFRFVTKYSDVDSLLDAEHNNHTEIRFSINTPRIINEHEHYTASANKRIESA
                     VKLARAGYQIGFIIAPVFLYEGWKEEYKNLIISIKEALPKDFDKKIIFEVISHRYTTK
                     AKNRILEIYPDTLLPMENEDRKFKYGQFGYGKYVYDKEQLDDMKEFFLKEINGVFKNS
                     LIKYII"
     gene            38830..39741
                     /locus_tag="KR231_001752"
     CDS             38830..39741
                     /locus_tag="KR231_001752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HBH0004131.1"
                     /translation="MHAWESIQITLDLIEANLSEEISINELANKANLSPFYYQRLFKR
                     LVNKTVMEYIKLRRLARASEYLAEHKNRILDVALNFGFASHETFTRSFKKAYGLTPEK
                     YRANPVKLNHFIKPELILNYAMVDEGVPLIADDIVIEVNRKTLSNPRTFVGIEIEVPI
                     CQLVGGETTGIAIVEELWMKLGSQRHNIPNQIPGGNEFAALYMGNAKEGNCMYMAGVE
                     VESGTSVEGYSTFELPAKEYLVCGFEAENFNELVNSAVFKADKFMERWMKKHNLTTTD
                     FAIEMYYPTTPEAAYLEHWIVPVPIEQ"
     gene            39756..40172
                     /locus_tag="KR231_001753"
     CDS             39756..40172
                     /locus_tag="KR231_001753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3788 domain-containing protein"
                     /protein_id="HBH0004132.1"
                     /translation="MNWQDAFFQDTKPTFEQINEFINNPLWDKLNKTLVSTYNVEPKL
                     EYSKCSMQRGWNVKYKKRGKSLCTLYPQEGYFKALVIVSESNRVEVDLFINTCCDYIK
                     KIYNEVNFFNGSKWLMIQVDSLLVLNDMLELIKFRA"
     gene            complement(40272..40664)
                     /locus_tag="KR231_001754"
     CDS             complement(40272..40664)
                     /locus_tag="KR231_001754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBH0004133.1"
                     /translation="MSINTEKNITKNVEELTCPIRYALDIVGGKWKLPIICMLAVENP
                     IRYSSIKRKLDGITNTMLAQSLKDLESTGIVHRKQYNEIPPKVEYTLTSKGKSIVPIL
                     QQFANWGATNMQEKNTCGLSCKECRKIK"
     gene            40805..41200
                     /locus_tag="KR231_001755"
     CDS             40805..41200
                     /locus_tag="KR231_001755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxamine 5'-phosphate oxidase family
                     protein"
                     /protein_id="HBH0004134.1"
                     /translation="MKALEFLNKARVYYLATVDENNQAHVRPLGFVMEYNGKLTFCTS
                     NQKDMFKQLIFNPKVELCCIDQNLNTLRILGEAVFVTSKETQAKALEIMPSLGQMYSV
                     GDGKFEIFSIDKAKVSCCSMSGKKIDVEL"
BASE COUNT        16956 a         4238 c         7525 g        12791 t
ORIGIN      
        1 aagtttaaga taagtcaaaa ataggagaat tgaagaatga atataccaat agtggttaat
       61 gaaaaatcta aagacataat aaaagattgg caatatacat gtacaaatga agatataaaa
      121 tttacaagca taataatatt gacatataat caaatagaat atactaaatt atgtattgaa
      181 agtattagga aatttacccc aaagaataaa tatgaaataa taataattga taataactct
      241 tctgatggaa cagttgagtg gttaaaggga caatctgata taaaatctgt gtataataac
      301 aaaaacttag gatttccaaa aggatgcaat caaggtattg agttagctac tggtgaaaac
      361 atattgttgt taaataatga tgtaatagtt actccaaatt ggctctataa tttgaataaa
      421 gctttatggt ctcaagataa tataggtgct gtaggaccta ttacgaatgc atgttcatat
      481 tatcagcaaa ttgatgttga ttataagtca attgaggaca tgtttatatt tgcacacaaa
      541 ataaataaat ctaatattaa cctatggaaa tatagattga agttagttgg attttgcatg
      601 ttaataaaaa aaactgttct ggataatgta ggggttttag atgaattatt cacacctgga
      661 aattttgaag atgatgattt atcttttagg atgatagagt caggatataa gttattatta
      721 tgccaggata cttttataca ccattttgga agtgtgtctt ttaaagaaaa tcgtaataaa
      781 tatacagata taatgtatat taatagaaga aaatttgaaa ctaagtgggg atttaatcca
      841 gaatatagtg gaatgataag aacagatttg atttctaaaa tagatgatag tttggaggca
      901 aatattaatg ttttagaaat aggatgcggt ataggggcta ctcttttaga aataaaaaat
      961 atatataaaa atgcatcaat atatggaata gaaattagtg agtcagcagg taaacttgca
     1021 aagtatagtg cagatgtact tatagcaaat atagaaaaag taaaattgga ttataaaaaa
     1081 gatttttttg attatataat attgggagat gtacttgaac atttgattga cccatggaag
     1141 atagtcaatg aattgaaaca atatctaaag aaggatggtt atctggtatc tagtatacca
     1201 aatattatgc atgtttctgt tttaagaaat cttgtgttag gtaattttac atatgaagat
     1261 tcaggaattt tggacaagac tcatttaagg ttttttacat taaatgagat aacaaaaatg
     1321 tttaatgata gtaattacat aattaatagt attacagcta ctagtatgcc actttcggaa
     1381 attgataata gcttcattga tacaatatgt aaggaaagct gtaaagaaat gagacaacag
     1441 tacgaatctt atcaatatat agtaaaagcc tctaaaatcc tagatactaa aagatattct
     1501 agtattagta tgattaattt aaaatacgct ttaatgagaa ttgataatga attagatgta
     1561 gatagtaatt taagttatat atttgataat tataatataa ctgaaccatg ttttgttgat
     1621 gatattgaat atctaattga tacatttgtg ataaataaag caactctatt aaatagatta
     1681 ggagttgagg catttaacag aggtctagga gattttagta taaacatgtt tatgacagta
     1741 ttagagatgg atagagatga tattgactca atatataata taacaagtgt attatgtgaa
     1801 ttagaagaat ttgatactgc ttataattta attaaaaata gtagcgaaaa agtacagagt
     1861 gaaagtgata tacaagagat actttgtttt attgagggga agaaatatga ataatgataa
     1921 gatatgtttt ataacctgtg taaatgatga aaggctttat gaagaatgtc ttgtatatat
     1981 aaatagccta gacattccta aaaactttag tatagaaaca gtagctttaa gaggagccga
     2041 ttctattgcc tctgcttata ataaagctat gagagaaaca gattctaagt ataaggtata
     2101 cttacatcaa gatactttta taattaataa aaatttcata catgatattt tagagatatt
     2161 taaaaaaaat acagatgtcg gaatgattgg tgtagctgga gtaaaagata tgcctgtgaa
     2221 tggaatttgg tgggattctg ataaaaaagc agggaaagta tatgatagtc atacaggtaa
     2281 aatggatatt tatgaattta gtaactttga agaatgtttt aatgaagtta tggctataga
     2341 tggattaatt atgattactc aatatgatgt attttggaga gaggataagt ttgatgggtg
     2401 gcatttttat gatttgtcac agagtatgga gtttagacaa aataaataca aagttattgt
     2461 accaaaacaa aataagcctt ggtgtatgca tgattctgga gtagtaaata taaataatgg
     2521 atatgatgaa tataggataa aatttgtaaa agagtacata aatcttgatt tatatagaga
     2581 aaatttttat gaatttgata agaagaaagc aagtaccata cttaagagta ataagcatgt
     2641 aatggattgt atgaaagagg agcttacaga acaattaaga ttaaagaatt acaaggatgt
     2701 tttaggtatt gtttctaaaa ttgctcattt ttctgttttt aatcatactg gtttgtattc
     2761 ttgtgaagaa tgtgagagag cattgctaga atgtgcaaat aatttaccag aaatagaaaa
     2821 tacgaaatta tttacaaaaa aagatttaaa aagaagaaaa gtattacatg ttttaagtga
     2881 aggatattca acaggaggtc atacaagact agttaaaaat tggattgaaa ttgacaaaga
     2941 ctctgttcat tcagttgtaa ctacatggca atcagataca ctgccagact ggttattaaa
     3001 agcaataaat gatagtggtg gcgaagttat atctttggat ttaatttcag atgattattt
     3061 aaaaagagct gtagctttga ggaaaatagc ttatgactgg gctgatatag ttattttata
     3121 tgttcatatg tgggatacaa tacctgttgt tgcttttgga gttgatggga aaatacctat
     3181 tttacatgtt aatcactatg atagtacttt ttggttaggg acaagtattg cagatattgt
     3241 cattgatttt agcgaaacta gtcaattaat tacattagat aaaagaggca tagataaatc
     3301 tgaaatatta ccaatgccat taaaagaaaa agaagtattt tcaaaatctg aagttagaaa
     3361 acgatataat ttagaggatg atgtgacaat aatattgact attgctagtg aaagaaaata
     3421 caatagtgta aatgatatta attactttaa aattgctaaa acattgattg aaaatacaga
     3481 taatacaatt attattgttg taggagttga tacagagaat ctctattgga aaactttaag
     3541 taatgttaca gataatagag ttatatgttt tggaacaaca gcaaatatag atgattttta
     3601 taagatttcg gatatatacc tagagtcttt catggtagga agtcatactt caaaattaga
     3661 tgcaatttta tatgatttaa ttcctgttaa gtttaaaaat gaagtttcac caatttttac
     3721 aaatatgtgg aattttatag ataagtttga ttataagaat ataaaagagg ttatagacat
     3781 gataagaagg tacaatacta gtgaatttga cagggataag ataaaagcaa aacaatcgga
     3841 aataaaacat tttgttatag ataaacattg tattgaaata aaaaactata tagacaaaat
     3901 atataatgaa gttaatcatc ataaagttaa gtatgattta tataaaaatg atgaaatcga
     3961 ggactatcag ctttttgtag cattatatgg ctatatggta aaaaataaaa acatgtcata
     4021 ggtggtaaaa tgaacaatat tcatatcaat aaatttgaaa aaagctgtga aaaaaactgg
     4081 gattattttg tagaaaataa atctataaat ggtacatttc tgcaaactag aaatttcctt
     4141 aattatcatg aggagggaaa attcactgac cactcattaa taatatgtaa aggtgaagaa
     4201 atactagcag tcgtacctgc atgtgaaact tatgaagatg gtgaaagaat atttttttct
     4261 catttaggga gtacttttgg tggcattata ataagaagtg gttttaatga tattaggcat
     4321 gtaaatgcca ttacaaataa gttagaaata tatttacagg aacaaaattt cgataaagta
     4381 tatttaaaaa atacatcaag aatattttgt aaagaggata cttcattact agaatatttt
     4441 ttatttaaga ataattacat gttttatgat gaattaagta tgtttttaga attaagtaag
     4501 tataaagaag atatattagc caattttaaa tacagtaaaa gaagagattt taaatattct
     4561 ttgaagaata atcttacctt taaaagactg tatagtgatg aagatatagt ttgttttttt
     4621 aatttacttt ctaattgttt agatagtaaa ggagctaaag taatacattc agtagaagaa
     4681 cttttggagt ttaaaaataa tagattaaaa gatattgtag aattttatgc agtatatatt
     4741 gatgacatta tgatttgtgg gagcatggta tttaactttc aagaaagagt ttatcatact
     4801 caatatctag catcaaattc gacatataat aaatattatc caatgatatt tttatactat
     4861 aatctaataa aagatgcttt agagagaaat tttaagtatc tttcttttgg aattagcact
     4921 ctaaatagag gcaaatactt agatgagggt ttagctacat ttaaagaagg ttttggttca
     4981 agtgcaattt gtaacagaac atactataaa aatataaata agtgagaatc atgttttata
     5041 gagtttttag agtatagtaa atatctagta ctataatatt acataaaaat aattagttta
     5101 taaagaaggt ttgtatatga aaagattaat gattttaggc tcaattaagt attttgagaa
     5161 tattgttatg tcagctaaaa gagagggaat atacacaatt gtttgtgata atagaattga
     5221 tactcctgcg aaaaagattt gtgatgaagc aatagatgtt gatgtatttg attttgataa
     5281 aataaagaat atagctatag ataaaaagat agatggaatt ttaactggat ttacagattc
     5341 tttaatgaag ccatatgttt atattgcaaa tgaactaaat ttgccatgtg tgatttcttg
     5401 caatcaactt gaatctgtaa ctaataaggc tgttatgaaa aattatttta aaaataatgg
     5461 aatacctaca actgattatt gtattattga aagtttgaaa gatttagaaa aaatacaagg
     5521 attaaatttt ccacttgtaa taaaacctgt tgatggttat ggttcaagag gtgtatattt
     5581 tgtatcaaac atagaagaat taatagaaaa atttgaatat tctaaggaag cctcgcaaga
     5641 tggacaagta ataattgagg aattttatga aagtgaggaa atacaaggac tagcttgggt
     5701 tcataatgga gagtcacatg tattttatat tggagataga gagcttgtaa atatacatac
     5761 aggaagagct ggaaaaccag atagattaat ttatccatca aagtattgtt ttcaatatga
     5821 agaagaaata aaatccatat atcaaaatat aacgcaggct tttggcataa aaaatggacc
     5881 tctttatgta caaatgttag tgggagcata tggaataaag gtatctgaag taatgccaag
     5941 attacctgga ggttgtgact atatggctat ttctcaaata acagatttag acataggaag
     6001 tttatttgca aactttagtg tgaataatga agtaaatttt gatgaaataa agaaatataa
     6061 tatgcatcta tcaaaatgtg tatatgcatt accaatatac ataagacctg gcacaataaa
     6121 aaagataaat aatatagata aaatagaaaa cttagattat gtcactcaat ttctattact
     6181 agtaaaagaa ggagatacaa taggattata tgaagatgag agacaggatt gtggaagagt
     6241 ttatggagta gcaaataatg tatttgatgc aaatataaag aagaaatgta ttcatgaaat
     6301 gatagaaata cttgatgaaa ataatgaaaa tatgatagaa aatttttaaa taagggagta
     6361 tgatagatat gaagctaata actcatgaac aaattatgtc attaaacatt tctcagaaac
     6421 aaggatacga gtggataaaa gaatcctttt taacaaaaaa agattgtcaa ttaccaccaa
     6481 aaataagcat ggtagaagaa gggcatgtat tttacaatgt aatgccgtcc ctaaatcata
     6541 atcataagat tggtggaata aaaatggtta caagattgcc agggagaaat ccaagtttaa
     6601 attcagagat atttctatat aatatggaag atgctaaatt aaaggctatt ttagatggca
     6661 attatattac agcttttagg actgctgctg ttgctgcctt ggctatcgat acatttgcta
     6721 aaaaagattt taatactatt gctattatgg gtttaggtgt aactgcttct gctataatga
     6781 atatgctttc atatactctt aaagataaaa atataaatat aaagttactt aaatataaag
     6841 accaagcaga gtcgtttgta aaaaagtatg aaaaaaatga acaatttagt tttgaaatat
     6901 gtgacacaca tgaagaactt attgtagatt cagatgtagt tatttctact gtgacatata
     6961 cagatgaata tttatcagaa tttaaatggt ttaaaaaagg tgctttatta ttacctgtac
     7021 atgttatggg atttggaaat gttgattatc tatttgataa agtatatttg gatgattata
     7081 atcatttgaa acatctagaa aatatagata gatataaata ttcttgtgaa ttttatgatg
     7141 ttttaagtaa acaagctaaa ggaagagaaa atgatgatga gagaataata tcttacaata
     7201 taggtttgtc aatacatgat atattatttg caaataaaat ttacgaattg tgtgaaacac
     7261 taagctgtga agaaatagaa ttaaaagaac caaaagaaaa atattggata tagtttattt
     7321 cattcatatt tacaatagtt tattgtaaat atgaatatga agtaatatat tgttagaaaa
     7381 ttagcatgaa taggatagat aaatttatgg ataaatataa tttaattagg ttcgtatcta
     7441 ttggaaacga atatatagga aatttagttg cattagaatc aaataaagca ataccttttg
     7501 atataaagag agtttattac atatatgatg taccaaacaa tgtaaagaga ggatttcatg
     7561 cacacaaaaa cttggaacaa gtactagttt gcctaaatgg aagtgtgaag ataaaatgtt
     7621 atgatggtgt aaaagagact atatttaatt tacataaaaa tgatgttgga ttatatatag
     7681 gaacgggagt gtggcatgag atgtttgatt ttgatgaaaa aactgtttta atttctatag
     7741 catctgaaca ttataatgaa gaagattata ttagagacta taaagaattt ttaaagtatt
     7801 taaataatgt gtagttatta tacaattagt gatgtatttt cttaattaaa taaatttaag
     7861 atagccacat agagaataga tagattagga tgtgaattta ttgttggtta aatttaataa
     7921 tttattaaaa cagttccaaa ctcataaaga agaatatgaa cagaagatta aggatgtaat
     7981 ggaaagtgga tattatatcc ttggaaatga agtaaagcat tttgaagaag aatttgctaa
     8041 ctatgtaggt agcaaatatt gtgttggttt agccagtggt ttagatgcac tgataattgc
     8101 ttttagagca ttaggaataa gcaaaggtga tgaagtaatc gtgcaatcaa atacatatat
     8161 tgctagtgtt atgggaatca gtataaatgg agcaacacca gtatttgtag aaccaaatga
     8221 atattataat atagattcat ctaagataga agaaaagata aatagcaaaa caaaagctat
     8281 attagtagtg catttatatg gtcaagcaag taatatgaaa gatatacaag aattatgtga
     8341 taagtataac ttgtatttaa ttgaagattg tgctcaatct catggagcta aatatgatgg
     8401 aaaaatgaca ggaacatttg gtgatatagg ttgttttagt ttttatccaa gtaaaaattt
     8461 gggtgcattt ggagatgcag gagctatagt aactagtaat gaggaaatag ctgataaagt
     8521 gaaaattctt agaaactatg gctcagaaaa gcgatattat aataaatttg tcggatataa
     8581 ttcaagattg gacgaaattc aggcaggttt attaagagta aaacttaaat atctaaatga
     8641 aattgaaatt gaaaaatcaa aaatcgtaga tagatatctt aatgaaatta ataatcccaa
     8701 agtcatactt ccaaagatag aaaataattg tactcatgta tggcatttat ttgttttaca
     8761 agttgaaaaa cgagatacat ttatggaata cttaaagaaa agtggtatag agtctataat
     8821 acattatccg ataccaccac atctatctga agcatatgct tatttgggat ataaaaaggg
     8881 gagttttaat atagctgaga actattcaga taaagttgtt agtatacctt tatttattgg
     8941 tatggaagat gaagaagtta gttatataat taaaattata aatgaatatt aaactactca
     9001 taataatatc aaaaataaat tttttatata tcatttattt aaatttcgtt aattgacatt
     9061 tttaaatatt gatatattgt acaaataaaa ttgaaatata tggaaaaata tagaattaag
     9121 atgagatttg tcttatattt ttataaatta aaaatatttt caaagagttt attataaaat
     9181 tgtaaactat agtgtttata atctttgtaa ttattggtaa ttaaatttaa aaaataaaat
     9241 atttaattat acacaaaaaa gatatttaaa aaatttgtta tttattgtat acttaagtta
     9301 aaactaaata ggcaaatcta gagaaatcta gtgacgcaaa gctataggga ctaaggttta
     9361 tatacataaa ctatgtcagc cagttgccaa aaagagtcct aggtgtattg tatacctaag
     9421 aaaagtctat aatgactgcc tttttggcag tcattttgtt atggaaaaat cactttattt
     9481 cagtagaaaa tacacataat aacatatttt accaattata acataaaata aagaaaaatt
     9541 atctcaaaaa gttactattt tacaaaaaat gacttcttta tttatttaaa ttaatcgcat
     9601 ttccattaca ttaatacaat aatgtatcaa tttagtaaga aaactaatat ttttttaatg
     9661 aagtcccatg aaaatataaa aaaattttaa tatgtattta aatatttctt cgaaaagttg
     9721 ctctttttgt aatatagcaa cttcattttt tttattaata aacaaaatag ataaaatata
     9781 ttttgaggag gggtgagtgt gaatacatat gacattataa aaatgggatt agatgcaact
     9841 aatctaagaa gtcagacaat agcaaataat atagcaaata taaatactga aggatataaa
     9901 agacattata taacttttga agaaacacta aatgatgcta tgcctaaaat agaagaaaaa
     9961 acagacaatt ctaaaggttt aagagtagat ggtaataatg tagacataga agaagaaaaa
    10021 gtaaatcaag caatggcaac attacaatat aatgctttga taagttttgc aaatggaaaa
    10081 atagcaatga ccaaatcaat aataagtggg aggtaattag aagatgagtg tgttcagtgg
    10141 aatgagaata tctgctagtg gattaacagc agaaagtttg aaaatggata tcatatcatc
    10201 caatgtagct aatataaatg ctacaagagg tccaaatgga gaagcatata ggagaaaagt
    10261 tgtttcattt gaagaaaact atgataataa attaggtatg ctaggagtaa aagttacatc
    10321 tgttgaagat gataaatcac ctcttaaaga agtatatgac ccatctcatc cagatgcaaa
    10381 gccaaatgga tatgtagaat atccaaatgt aaatatattg gtagaaatga cagatttaat
    10441 aacagcttca cgagcatatg attctaacgt agatacattg aatgctcaga agtctatgat
    10501 atcaaaagct ttggaaatag gaaagtaggg ataaattatg ccaattacac aaattaacaa
    10561 tttaatgcaa ggtgcaaagt tagataattt gattggagaa gcaaagccat taactcttaa
    10621 taataaagaa gaaaaaaaga attttgaaga tgtaataata gatactatag ataaagttaa
    10681 ttttcaacaa gtaacagcag atgatatgaa agaaaaattt ataaaaggcg aagatgtttc
    10741 tatgcatgaa gttatgttaa taggtcaaga agcacaacta tctatgcaat atttaataga
    10801 agttagaaat aagattcatg atgcatatca agaaatgaat aaggtgcaaa tttagccttt
    10861 tgaacaggag taataatcaa tgataaccag ttttaaaaat aagattaagg agcaagttgc
    10921 taaatctagg acaaagataa gttctttaaa aaagggaact aaaatagcat taggtatagg
    10981 ggttattgct atatgtttag cgctagtatt tacagcaata tctgcgagca aaaataagta
    11041 tgcagtctta ttttcagaac tagatgctca agatgctgca gatatatcag cagagctaga
    11101 gtctaaaaag atagatacta aggtaaaagg aagtacgatt tatgtaccta gaacagaagt
    11161 tgataagtta aggctggagt tagcgccaag tcttacaggt ggttctaaag gatttgcact
    11221 aatggatgat agttcatcaa tagggcttac tgatgaagaa tttcagatta agaaacaaag
    11281 aatgatacaa ggtgaaatag aaaaaacaat aaagagtttt ccacaagtgg aagacactag
    11341 agtacatata acatttggag agtcatcagt atttgagaag gaggctgttc cagggagtgc
    11401 agcagtttat ttgatgctaa aaccagggac gactttagaa aaaaaccaaa taaagtctgt
    11461 tatggcactt atatcaggaa gcgttacaaa tataccagag aaaaatgttc aggttattga
    11521 taacaaaatg aatttattat ctgaaggtat tttggaggat gaaaatgttg atgaaaataa
    11581 tcaaccaata aatagtggca ttagtgttga taaaaataag gcatctgaac aagcattgaa
    11641 taaacaacta gaaaagtcta ttttagaaat gctagaaccg atatttggta agggaaaggt
    11701 gaaagctaca gtaaatgctg atttaagttt tgatacagct gaaaaaactg agataaaaat
    11761 tgaccctgat aaagttgcaa taaaggagac aaggtcgaaa aattcatcta aatctgctgc
    11821 aaataatgtt caaggtgtag atgctaacat gaataaccaa ggaaataaca atggtactaa
    11881 tacagaagat agtttagatg agagttttga gtatgaaaca ggtaagattg aaactcacac
    11941 tatagttgcg cctggagaac ttaatagatt gacagcttct gttgcaatag atggaaaaat
    12001 agctaaaggt gttcaagctg atgtagagga tattgttaat aatgctatag gtatggatgg
    12061 agcgagggga gatactctta gcgttgtttc aatggtattt gacccagaag gtaagaaaga
    12121 ggctaaacaa gagctggaag agattaaaaa agaaggattt aaaaagaaca taataaaagc
    12181 agttattgga gtagtagcag taatagcagt tggagctatt ggatacttaa tatataagaa
    12241 aagaagtgaa cgagaagata tggattatga agatgaagat tatatttcta aatctgattc
    12301 tgttgatagg aaggataatc ctctattagg agatgatcca gaactgacat tagaggaagc
    12361 tgttaaaatg tatgcagaag aaaagccaga ccaagtaaca gagataataa agacttggtt
    12421 aaatgagtaa gggggataga aagtgtccac ggaaattaca aatgttaatg cgtttgactt
    12481 aagtgatata aatgaaagtg ataagaatga gaaggtagaa ggtgagggtt taaaaaaagc
    12541 tgctgtatta ttaatgacat taggcccaaa tgtgtctagt gatataataa aaagcttgcc
    12601 tgataaacaa gttcaaaaaa taggtttgga aattgcaaat atttcttcaa tagcttcaaa
    12661 agaaagaaga gaaatcttaa aagagtttgt agaaataaat agggcaaaag attatgttat
    12721 agaaggtggg cttgaatatg caagagagtt attaagtaat gctttaggaa atgttaaagc
    12781 aaacaaatta cttgaaggta tatcaataaa tacaagtaca aagcctttta aacatattat
    12841 aaaactagat gtaaagaaga tattagaaat acttaggaat gaaagtgcac aaactatagc
    12901 cgttttactt gcacatatgg aaccagaaaa tggagcagaa gttttatcat acttagattt
    12961 tgatttacaa aatgaagtag ctatgagaat aagctcaatg ggttcaatat ctccagaagt
    13021 aataaaggta attgaaagtt cattagaaga taaattacat tcaataagtg gtgatgattt
    13081 taatgattat ggaggggtgt ctaccttagt tcaaatattg attaattctg atagaaaaac
    13141 agaaaagaat attttgggaa ctattgaaga acaaaacccg gatttagcag ctcaaattaa
    13201 atctcatata tttgtctttg aagatattgt caagttagat gatataagca tacaaaaagt
    13261 gttaaaagaa gtgactatga aagatttagt atatgcctta aaaggtgtag atgatgagat
    13321 ttcagatgct atatatagaa atcaatcttc tagagcagca gatgcactta aagaagaaat
    13381 ggaaatggtt ggtgttataa aggttacaca agttgaggct tctcaacaaa agatagctaa
    13441 tatcgtaaga aaacttgaaa gagaaggtgc cataactatt gtaaggaatt ttggtggtga
    13501 ctttgttgaa taataagatt attaaaagta aaaaagcatt atataaagga gtgctagatt
    13561 taaccataat agataaagtt agagtgggag aatcaaatgt aaataaagaa aatgattgta
    13621 gatttaggga tgaggtaata aaagaagcta tagaatctgc tgagataaaa aagaatgaga
    13681 tattagaaga agcaaaaata aatgcacaaa atatagaaaa gcaagcatat gaaaaagggt
    13741 atagtcaagg tcaaaaaaat ggatatgagg atggatataa agagtcatat gatgaatata
    13801 cccaaaaagc taaagatgaa gcagatttta taaaaaatca ggcaaattta atcttattac
    13861 aagctaatga gaagatgact gagtacataa aagaaaaaaa taaagagatt gtaagacttg
    13921 ctattaatat ggccagttct gttttaaaaa agcatttcga agatgaagaa tctatgagtg
    13981 atctgttaaa gcaaattatt caagattatg aaggaagtag ttcatttata gtaagatgta
    14041 attctttcta taaagataat atagagaaag agtttgaatt attcaaagag gaaacatcac
    14101 taaaatcaag tgtatttgtt attgcagatg atagtataga taaaggcaat gctattatcc
    14161 aaaaggaaaa tggaagaata atagttggta ttgattgtgc tatggaaaaa ctaaaagaag
    14221 aattgcttgg tgaataaagt atgtataaaa ctgatatatc tatagatttt gacaaaataa
    14281 ataagaaaat agaaaattta gaactcacta tatcagaagg tagagtaaag aagataatag
    14341 gacttactgt agaagttgaa ggaataaaag cttttgttgg ggagttatgc gttatataca
    14401 accaagttaa taaaccagtg aattgtgaag tagtaggttt taaagataaa gaagtcatat
    14461 taatggcgtt gggagaatta acattgatag cacctggttg taaagttatt tctaagggga
    14521 tacctttaag tgttatgtgt agtgataatt tactaggtaa agtacttgat ggtcttggaa
    14581 atcctataga caactcagat gctgttttag gagatagata caacctgaac aatgaacctc
    14641 ctgatccaat gaagagaaaa aagatacgaa atataatgga aacaggtgta agagcaatag
    14701 atgcatttac tacttgtggt gaaggacaga gaatcggcat atttgcagga agtggagtag
    14761 gtaagagtac gactctaggt atgattgcta ggaatgcaaa agcagatgta aatgtaattg
    14821 ctcttattgg agaaagagga agagaagtac tagattttat tgataaagat ttaggtgaag
    14881 agggaatgaa aaaatctgtt gttgtgtgtg caacatcaga taaagcccct ctagttaggt
    14941 taaaaggtgc tcttactgct actgcaatag cagaatattt tagagaccaa ggcaaaaaag
    15001 taatacttat gatggattca gtaactagat ttgctatggc acaaagagaa gttggtgtag
    15061 caataggaga gccaccagct caaaaaggat atacaccatc tgtatttgca atgttgccaa
    15121 aacttatgga gagaacaggg acatcagata aaggttctat aactgcattt tatacagtat
    15181 tagttgatgg agatgacttt aatgagccaa tagcagatac aacaagaggg atacttgatg
    15241 gtcatatagt tttatctaga gacttggcaa ataagaatca ctatccttct atagatgtat
    15301 taaacagttt aagtaggctt atgaatgaaa ttgcttcaaa agaagacata aaaatagcgt
    15361 cttttgcaag agacatgctt gctgagtata gagaagcaga agatttgata aatataggtg
    15421 catatgcttc aggtacaaat aaaaaaatag atgaagcaat ctattatcat gagcatatta
    15481 ttaatttttt aaaacaaggg ataaatgaaa agagttcttt taatgaaact ataagtagtt
    15541 tgagaagagt ttttgaataa acaattaaaa aaatatttga ataggttgtg atggaattgg
    15601 ataaaaactt taagtttaga ttacagaaag ttttagactt aaaagtgaaa gatgaagaag
    15661 agataaaaat ggaatttgct aagattcaac aaaaaaaaat agatatagag actaatttag
    15721 aaaacttaga aagtaattat agcaaatatt ctataagtaa aaataacgat agtattcaaa
    15781 atcaaaaaat aactattaac tatttactag ctttaaacaa ttctataatg gatttatcag
    15841 aagagttgga taagtcaaca aatgaacttg aaaaagctag aaagcagctt ataagcaaac
    15901 agatagagag aaaatcatta gaaaaattaa aagaaaaaaa gtatggacag tattataaag
    15961 aagaaaattt aaaagaacaa aacactaatg atgagtttgc aagtatgagt tatttaagga
    16021 atagacaagt tctataagaa tagtaggaag tgaggatatt attgtatgaa gatacaagca
    16081 gattcttata atattattaa agatattggg gatagaaaaa gttcatctaa gaacaaaaat
    16141 ataaaaaata ataaatttga agataatcta tataaggcaa cagaccataa aaaagttaaa
    16201 gatagaaggg aagtaagtaa gcaaaatatt agctcagata aaccggaaaa tagtgataat
    16261 gagtgtcatt tagatgaaga taaaagtaat cacttagaag atgaaaatac atatgaaaaa
    16321 gattgtagta agaataatga agctttgcag caattactga atcttttaaa ggataattat
    16381 aaaaaagata aagatataaa cactatattg aataatatag aaaaactaag tatatcagat
    16441 gaattaaaac aagaacttaa gcttaataaa aatatattaa ataagattgc aaatcaaaat
    16501 tcagagctaa ataaagctaa tataaataac tctaatgata tagaaaattt agacatagtt
    16561 aaattaagag aacttttgga agataatgct aataaagata ttgaagtaat tactaaaact
    16621 acagaaaatg ataccaaaaa tatagatttg tatagttttg atagcaatag aatggataat
    16681 cttaactcaa ataaacagaa agatgatagc tctgatattt tggaaaaact agcaggggta
    16741 aatggaaata agagtgggaa ttttggacaa gtaataaata aaaatgttga tatgaataaa
    16801 attaaaaatg ataatgtcaa tttaaaacag atagaatcaa atgtaatgga tgactctata
    16861 aaagctatta agcatatgaa aacaaatgat atacaagaat tgacaattaa attaagacca
    16921 aaagaattag gagatatgaa tatacaattg ttaaaagatg gtgaaagtat gagagctgtt
    16981 gtgactgttt tcaataaaga tgtctttgac tctataaata aaaacatagc agatttaaag
    17041 caacatcttg aacttactaa tgtaaatata aaagatgtat cagtgcaaat gcacagcgat
    17101 aatacaaata catctgatac ctttgataaa gcatttgaac aacagaatag acaaaataac
    17161 caagaaaaca tgagtaagaa gaatacaaat gataagcata ataatgtagt catagaagat
    17221 gacattaaag aaaatactat tgatgatgat agagtagatt tactagctta gtaaggggga
    17281 agtattgcat gtacggaata gcaacggctt tggcaggaac tcagggaaac tataggtcaa
    17341 ataacttaag ccaacttgaa agaaatatta atgatattgc caataaacaa gttagaagca
    17401 aaggaaatca gacagtaaca gacaatggga ctccaattat aggacaaggt gatgatgctg
    17461 ataaagactt gtttatgaag atacttgtgg cacagatggg taatcaagac ccaatgaatc
    17521 cgcaagaccc aacagaatat gtgtcacaat tagcacagtt tgcaacttta gaaaagatgt
    17581 cagctatgaa tgagaagcta gatgtacttt tagccttaag taattccact ctaataaact
    17641 ctgctttaag tatggcaaca tcattaattg gtaaagaagt agaagtatct ggggaagaga
    17701 aagaagatga aaacattgta ggagtagtaa agtccacata tataaaagat ggggaagtac
    17761 acttagaatt agaagtagat ggaagtgaca aaactgtagg tgttaaatat gaaaaattac
    17821 ttaaaatagg agaggtagat gaaaattcag gagaagaaaa tgattcttca gaacacgaat
    17881 ctccagaaga agcataatat taaatgagaa aagaggtaaa ttcatgataa aagcaatgta
    17941 ttcaggtgta agtggaatga aagcaaatca aacaaaatta gatgtaatag gtaacaatgt
    18001 agccaacgct ggaactactt cttttaagaa aagttcagct agaataacag attcatttta
    18061 tcaaactgta ctatatgcaa gtgctccaac agctgcatta ggaggaacaa acttaggaca
    18121 agtaggtgta ggtagtaaga tatcaagtat aaataaagat atggtacaag gaaatgtaca
    18181 accaactaat agaccatctg atttaatgat agatggagat ggatatcttc cagtagtaag
    18241 acaaggaaca gttatgtata cgagagatgg ttcttttaat ttagatacag gatttaaagc
    18301 agctgatggt gctttgaaga atattaaagg tggaagactt gtaaatggtg atggatatat
    18361 gttacaaggt atgatttatg atggggaata taaagctgat actggagaat ttgttaaaaa
    18421 gggtgatgct aaaggaaaag agcctattgt aataccactt caaagtataa gtcctaagga
    18481 tggaacagtt caaaatgtac tagagtataa tatatcaaag gatggaacag tagaattttt
    18541 attgagtgat ggtcaaagaa ctcaatttgt ctatgatata cctgatggtg ctaaggtagg
    18601 agatacacct gctggaatag ataaattaaa aggtacaata caaaaagtgc aaacatatgc
    18661 attccaaaat ccagcaggac tagatgcaga aggaggaaac ttgtttaaac catcagcaaa
    18721 ctcaggagac ccacaaatag caggagctac aggcacaata atacaagggg caatagaagc
    18781 ttccaatgta gatatagcag aagaatttac agaaatgata atagcaagta ggtctttcca
    18841 agcaaacagt aaaataatat cgacatcaga cgagatactt caagaaataa taaatcttaa
    18901 gagatagtag gtacatatta tgataagagt aacggattta aacggaagaa aatacatatt
    18961 aaattcagac cttatagtga ggattgattc tgtaccagaa agtaggattc tccttacaac
    19021 aggagaaaaa aaccttgtaa aagagtcggt agatgagata gtagataaag taataaagta
    19081 taaaagaaaa ataaatgtag gttatattag gagcgaaaaa taatgaaaaa aacagattca
    19141 ctgacattta ttggactaat agtatctaca gtattagttt tagttggtgc cgcaaaagga
    19201 agtagttcag ggttaaagaa tttttttgat gtttcatcaa tattaatcac agtgcttggt
    19261 tcatttggag ctctaatgat tacatttact atagatgata taaaacttat aaaaaatgca
    19321 ttacaatact catttaagac aatgagtgta tcaaagttag atttactaga acaatttaaa
    19381 acactttcta aaaaagctag aaaagaaggt cttttatcaa tagagagtga tgtaatggga
    19441 atagaagatc catttatgaa gaaagggtta gagctgtgta ttgatggatt ggaaatcaat
    19501 gagataaggt ccatcttaga actagagata gattctgttg aagatacaaa taacagatac
    19561 tctaaactat ttaaaacttg gggaaccttt gcacctgctt ttgggatgtt gggaacacta
    19621 ataggtttaa tacaaatgtt agctgacctt acatctccag atttaatagc atctggcatg
    19681 ggaaaggcat taattacaac gttttatggt tctttacttg ccaatatcgc tttgaaccca
    19741 attgcatata atatagatga gaagactgaa aaagaaattt atgtaaagga aatgatgttg
    19801 gaaggtataa taagcataca atctggggag agcagtatag tagttgagga acgtttagcc
    19861 acataccttt caaacaatga gaagttagaa attatgaaat ccaataaaaa tacagaaaga
    19921 gcaatgagca atggcgcgta aaaaaaataa gaaaaaggat gagataaatc cagatgcatg
    19981 gctggctact tatgcagata ctataacact gattcttaca tttttcgtat tattgtatgc
    20041 aacatcagtt gtagatatgg aaaaatttaa aaacatagca gatgcgttaa aaggtcagtt
    20101 ttctgggaca agtatattta gtacgggttc aagtacaagt gagaaatctc caatagacag
    20161 tgttttagtg gataaaaatg ataaatcaaa tttagaacag gatttaaaag ataaagttaa
    20221 taattctaac ttacaaaata gtgtaacagt caaagatgat agtagaggga ttttactaga
    20281 gttagatgat tcaattttat ttgactctgg gatttctgag ttaaaagtag atagtaaagc
    20341 tactcttaat aaagtatatg acatgataaa gatgatgaaa aataagatag ttatagaagg
    20401 ccatactgat aatgtacctg taaaatcaag tacacatgaa tccaattggg atttatcttc
    20461 tagtagagca gtaagtgttg taagatactt tgtagaagaa aagggcatgg accctagact
    20521 attttcggca acaggatgtg gagagtatca acctttggtt tcaaatgaaa cagcaaaggg
    20581 aagggctgag aatagaagag ttaatatact tataactatt gactaggagg aagaggtttg
    20641 ttcaaaaata aaaaaattat tataattatt ttgatactga ttattttctc agcgggagca
    20701 ggttttttta tattaggaga aggtggaaat aaacaagttg acaagattgc agatttgttt
    20761 attccaacag gaaaaggtaa agatgaagta aagaccgaaa atcttgactt agaagagatg
    20821 gtattaaagc tagctgatga aggtgtaaga tatttaaaag tatcaataac tgtatcttat
    20881 gattcttcat ataaagatat agaaaaaaat acgcctttaa ttagggataa tattataaat
    20941 tgttttatgg caaaaagggc agatgatttt actgctgata atttaaagaa cataaaagaa
    21001 gaaataaaaa atacattaaa tatacaacta ggtgaaaatg taattcaaaa tatatatttc
    21061 acaaatatag tagtgcaata aaaggatggt aagacatgat actttattta ctaaaaatat
    21121 taatatgtat cccaataatt ttaatattga tagtcttatc tttaaaaatt agccaaggaa
    21181 ctttattaaa aaaatataat gataaatatg taaaaatact agatattgta aatataagta
    21241 aaaacaatag cataataatt ttaaaaatag gtgaagaagg atgcattatg gcatcttctt
    21301 cttctagcat gagtaaaata aaagatttga ccaaagaaga aatattaaaa atagaaaacg
    21361 acattaaaga aagaaatttt aaaattcaag attttaaaat ggaaagaatt aaaaagaaat
    21421 atgatttcag tagatatatt ggaaaattta caaaaaagga agataagtaa atggaactat
    21481 tatcaaaatt acctttggct gatgtaccat atacaagttc aatgcaattg tttttatttc
    21541 taactgcatt aatgttttta ccatttgtaa tgttcatgat gacaagcttt gtcagaatag
    21601 ttataagttt atcatttttg aaatcagcat taggagcaca gcaagcaatt ccaagtcaaa
    21661 ttttggtagg acttgcaata gtattgacaa tatttataat gagaccagta ttaaatgaga
    21721 taaacgaaaa ggcattacaa ccatatatga aagaagaagt tactatggaa gaagctatga
    21781 aggaagcaga aggacctatt aaagagtttt tattaacaca aaccagacag acagatttag
    21841 atttatttgt agaacaggct ggtttaaaag aaaagaaatt aactcgtgaa aatataccac
    21901 tatctgttgt agttccagca tttgctataa gcgaactaaa aactgctttt caaataggtt
    21961 ttttaatata tataccattt ttgataatag accttgttgt ggcaagtgtt ttgatgtcta
    22021 tgggtatgtt tatgttgcct ccagtcatga tatcattacc atttaagtta ttattatttg
    22081 taatggtgga tggatggaac ttgatagtaa aaacattgat attgggattt ggataggaga
    22141 aaaatagtat gagtgaattt atgataatga gtgttcttaa aaatggcatg tttacaggag
    22201 ctatgattgc agctccagta ctcattgttt ctcttgtagt tgggctttta ataagtgtgt
    22261 ttcaagctac aactcaaatc caggagcaaa ctttgacttt tgtaccaaaa ctaatagcta
    22321 ttcttttagt agtagctatt ggtggaagct ggatgttaca tactcttatt agttttactt
    22381 ctgagatatt caatatgata tctcttataa ctaaataagt aggatacata tgatttttgt
    22441 atttattaga atagtagcat tctttggaac actaagaata ctatttccag ctggtacacc
    22501 tgctttattt aagtcactct ttgcaatcat tatatcaata ttgatttcaa gtactatgca
    22561 aattgaatat gcaacaaata tagacaacat tgtattgttt accttatatg gtgtaaatga
    22621 gaccataact gggattatgc ttggatatat aaccaaccta tgtttttata gtatcagaat
    22681 ggcgggttct atgatggacc aacagatggg attatcaatg attaatatgt ttgacccaaa
    22741 ttcaatgact cagacaactt taattgataa tcttatgaac tggacagcac ttatgatatt
    22801 ttttagcatg gatggtcatc atgttttaat tagaggtata aggtatagtt ttgagttaat
    22861 tccaatagga aaaccatttg tagataataa catagattat ataataaaca tatttgtgca
    22921 gtgcttttta actggattca aaatagcaat acctattgta ctttgtctgc ttatggcaga
    22981 ttttatttta gggcttatat caagaagtgt acctcaatta aatgtaatga tagttggtat
    23041 gccattaaaa atattggttg gtattgcatt atttatcata tcaatacctt taattgtcaa
    23101 tcaaataagt catttattaa gtcaaatacc aaagatgtat gagggaactt ttgcactagc
    23161 tcctatgttt tttatgggtt cagcagataa aacagaagaa gctactccaa agaaaaaggg
    23221 agaacaaaga aagaaaggta atatagcaaa gagtagagaa ttacccgttg caatgactct
    23281 acttgcattc accttattag tacctacatt attttcatat gtagtagata cacttaaatc
    23341 ttcgcttaat tattttttga gtctagattt ttatatgaac ataaattatt caaacctaga
    23401 gaaattagtt atagcaggat taatggattt ttttaagata tttttaccaa tagctattcc
    23461 ctttttagtt ttaggcataa tagcaaacct atttcaggtg ggaatactgt ttactggtga
    23521 aactttaaaa ccaaatttat caaaattaaa tccaattagt ggattcaaaa acatgttttc
    23581 tatgagaagt ttgtcaacct taataaagga tacagcgatt atatctattt tggcttacat
    23641 aggatataca ttcttccaag ataattattt agatatatta aagctaggta acatatacct
    23701 accaacttta atgtacacag ttaaagactt agtatattca atattgagta agatttgtgt
    23761 agctatgata gctatagcag ttgcagatta tgtttatcaa agatacagtc ataaaaagca
    23821 actgagaatg acaaaacaag aagttaaaga tgaatataaa aactcagaag gagacccaga
    23881 agtaaaagct aagataaaac aaaaacaaag acaaatttcg tctcaaagga caatgcaagc
    23941 agtaccaagt gctactgtaa tagtaaccaa tccaacccac ttatctatag cagtgagata
    24001 tgaaaaaggg aaagaccaag ctccagtagt ggtggcaaaa ggtgcagatt atctagcttt
    24061 taaaataagg gaaattgcaa agggaaataa catccctata atagaaaaca aacctattgc
    24121 taggttgtta tataagcaag tagaaataga ccaagaaatt ccagaggaca tgtatcaagc
    24181 ttttgcagag atattagtgg cagtatataa aatcaaaaat agatacaaag tccccaaaag
    24241 gtaggataag taatgaataa gtttaattta aaggaaaata tggatgtaat agtggcattt
    24301 ggtgttgtag ggattgttct tatgatgata gtgccattac ctacatttat attagatatt
    24361 ttactggcaa ttaacataag tttatctgtg ctaattttac taatgacatt atttacaaca
    24421 aatgtacttg atttatctat atttccaaca gtgttacttg tgacaacact atttagattg
    24481 ggattaaatc tttcatcaac tagattgatt ttaacacagg gatatgcagg tgaagttata
    24541 gaggcatttg gaagttttgt tgtaggtgga aattacgtag taggaataat tatattctta
    24601 attatattaa ttgttcaatt tgttgttata accaatggtt ctggaagagt atctgaagta
    24661 acagctagat ttacgttaga tgccatgcca ggtaagcaga tgagtataga tgcagattta
    24721 aatgcaggag ttatagatga caaaactgct agaaaaagaa gaaaagagct tcaacaagaa
    24781 gcagattttt atggttctat ggatggagca aataagtttg taaagggaga tgccatagca
    24841 ggtcttatag taacagcaat aaacataata ggtggaattg taataggagc tgtaatgctg
    24901 aatatgactc ttatgggtgc agcacagaca tatgtaagac ttactatagg ggatggtctt
    24961 gtaagtcaga tacctgctct attaatatct acatcagcag gtataatcgt aacaagagct
    25021 tctactgatg aaaactttgg tgacttagta ggtaaacagt taacggcaat accaaaagca
    25081 gtaatgatga ctggttgtgt tctaatcgta cttggtatga tgcctggatt acctaaacca
    25141 gcattttttt cactaggtat aggagctata gcagcaggtt actttttagg aagagaaaag
    25201 aaagatactt tagaagactt ggagtttgaa aaacctgata tggtaaaccc agataaaaat
    25261 gaagtagaag atgtaacaaa tttaataaat gtagaatcaa tagaagtaga aattggatat
    25321 ggtttaatat ccttagctga tgaatcagca ggaggagatt tacttcagag aatagcatca
    25381 ataagaagac aatgtgcaat agatatgggt atagtcgtac aacccataag aataagagat
    25441 aacttacagt taaatccaaa ccaatacaat ataaaaataa aaggaaatgt agttggtggg
    25501 tatgagataa tgcctaatat ggttttatgt atggacccta tgaatcaagg atttagtata
    25561 tttggaataa agacaattga acctactttt ggaatagagg cactttggat agaaagtgac
    25621 aaggtagaag atgcagagtt aaagggttat acagttgtag attcatccac aatacttata
    25681 actcacttac tagatataat aaaatcaaat gcacacgaat tactgggaag acaagaagtt
    25741 aagactatta tagatgcagc aagagaaaat tatagtgctg tagtagatga attgatacca
    25801 gatttgatga cacttggtga aattcaaaaa gtacttaaaa atctgttaag agaaaaagta
    25861 aatataaagg atagagttac aatacttgaa acgcttgcag accagtctag aaatacaaaa
    25921 gatatagagc ttcttactga atatgtaaga atagccttgg ctagaagtat ttgtaataat
    25981 ttagttgatg atgataagac aattgtagtg gctacattgt ctccagaaac tgaagagttg
    26041 gtatctaata atttacagag gtctgtaaat ggaacttatc cagcagttga cccagaaaat
    26101 acaaataaaa tatttgaaag tatacaagaa gtaatgagca atgtatattt caatcataat
    26161 ataccagtaa tagtagtatc accaaagata agagctccat ttagaaaatt agttgaaatt
    26221 gtatatccta atttgactgt attatcatta aatgaaatac ctaacgatat taaaatcaaa
    26281 gcagaaggtg tggtgagcat atatgatgac gaaaaagtat acagctaaca caattcagga
    26341 tgctatgaat ctagccaaaa tggaattggg tgacaatatt acattaatag ataaaaaaga
    26401 ggtaagaaag tctggaatac aaggtatctt ttcaaaaaaa gatattgaac taactattgg
    26461 atgggaaaag agagaaaatg tagaacaaaa agatttaaaa cgagagatag aacaattaaa
    26521 gtcaattatt aacaatatgg ggtttgataa taagaatgat aatgatatag ataaaatatg
    26581 taaaaatcta ctaagtttag aattgaatga agaaattgta gaatctataa gaattgattt
    26641 gcaagaaatg aagttcaatg gaatcgatac aagtaaaaat ttagtagaaa ttttaaagaa
    26701 aaagattaaa atagaaaatc aagtaataaa tggtaaaatt gctctagtcg gaccaccagg
    26761 agtaggtaaa acgactacaa tagcaaagtt agccgcaaaa ttagtttttg aagaaaataa
    26821 aaaagtagga gtaataacta tagatacata caggattggt gctgtagaac agttgaagat
    26881 atatactgat ataatgaata ttccctttaa aggggtaata agtcctgatg aaatggaatt
    26941 ggcacttgac gagatgaaag attgtgatgt tgtattaata gatacaacag gtagaggcta
    27001 caaaaactct atgcaaatac tagaaatcaa aaatcttata gataaagctg aaactgataa
    27061 tatacattta gttttgaatt gtacaacaag agaaagtgat acaaaagcaa ttatagattc
    27121 atatagaaat gtgaatttta aaagcttaat aattacaaag ctagatgaaa caataacata
    27181 tggctcaata tttaacataa tgaattatgc gcaaaaacca atatcatata ttacaacagg
    27241 acaaaatgtt cctgatgata ttataaaacc taatgaagat aagattataa ggttactatt
    27301 aggagttgaa agtatatgat agaccaagct caaattttga gaaaaatagc aatggaaaaa
    27361 agaggacttg atgagtttat agtagagaat gagaatgtac ctaagataat tacaatagct
    27421 tctggtaaag gcggtgttgg aaagagcaat ctcgctacaa atttgtctat atgcttgacc
    27481 aaacttaata aaaaagttct tatattagat gcagacatag gaatgtctaa tatagatata
    27541 ataatggggg taaatgtaaa agggactata attgatgtaa ttaatggcga aaaaaatata
    27601 gaagatataa tttcacagac taagtatggt gtaaatataa tatctggagg ttctgccctt
    27661 aatcatatag aagactttac agaagctcaa agaaataagt ttatacatag catagaacaa
    27721 attcacgatg tggattttat aataattgat acaggagctg gtatgagcaa aagcctattg
    27781 tcatttatat actgtagtac tgaatttttc ttaataacaa ctccagaacc gacatcattg
    27841 actgacgcat atagtttatt aaaagctata agtaattttg gcataaagag aagtgcaaat
    27901 ataataatca atagggtaat tgatttagaa gaagcaaaat ctacatacaa aagaataaaa
    27961 atggttgtgg acaaatttct aaaccttaat ctagaattgt atggatatat aatagatgac
    28021 aaaaaagtaa gtttatgtgt aaaaaaacag ataccattca ttttagaata tcctacaagt
    28081 attgcatcaa aatgtattat agccatagca aagagaatgg taagtcagtc aagagaagat
    28141 attgttgata ataaaagttt tctaagaaag atgtttagta tatttaaaag ctaaggaggc
    28201 gtagttaatg aatagagaag aattaataaa agagaatatg cctcttgtaa agagtatagc
    28261 aagaaaattt tttataccag ggaaaggttt tgaatatcaa gacttagtaa atagtggagt
    28321 cattggattg attgatgcaa taaataaatt tgatgctgaa aaaggggcaa agttttctag
    28381 ttactcttat ataaaaataa aatctgctat attagatgaa attagaaatc aaagtccaat
    28441 ttctaaacat aatctaacta aagtaaataa gtataataga gtggtagaaa agttgcaatc
    28501 taaattatta agagagccaa cttcatatga aattgcaaaa gaattaaagg tttcagaaaa
    28561 agaacttcat gatatcgaaa gtaatataga tatgttaaat attgtatcat taaactatgt
    28621 aatctttgaa gatacaaatg aaactgtaca agatgtaata agtgatagag aagaggaagc
    28681 tccagaaaat ataatagaag aagaagaaaa gttagagatt ctatccaaag caattagtaa
    28741 tttaaatgaa agagaaaaat taatactttc actgtactat tatgaagatt taaatctaaa
    28801 ggagataggg aaagtgctag gtgtttcaga atcaagagtt tcacaactcc acagaaaatc
    28861 aataagaaac ttaagaaaca agataaaaga acttaaatat tctatataga tggtgattga
    28921 taagatgata caaattatat taatagtagt gtctatttta ataatagtaa ctatagttat
    28981 aaatttacat aaggaatcaa aaaataaaga taacagatac tttgataaaa tatttgagca
    29041 agaatatgaa gcaaatgata gattaataat tgcagaaaaa agaagattct ttttagacaa
    29101 agtacttgca gaaaaaagaa ttaatagtca tataaaagtt tatgaaaatt ataacctaat
    29161 aaaggctaat gaagaaagaa aggaaaacat atttatagaa tcaaaaaagg aagtaagaca
    29221 agaaaatgag ttatctctta aagtgaaaca tcttataagt tcaggttatg atgatgtgga
    29281 aatatgtaag atgctagata ttggaaaggg ggaactgtta ttaataagga gttgttacaa
    29341 aatataagga tattattatg tgataaaaaa gtattcttag gaataggtat tggtatatta
    29401 atatcaactt tatgtataat gctttttagt aataatgata tgagtaaggc agagatagaa
    29461 aaaaaggcca gagcgttagg catgaaatat acaagtgaga tgaaagtttt agaatagatg
    29521 atattgttta gacatttaca aaaaaggagg tcataatgtg ataagaggat tatatacagc
    29581 agtttctgct atgataacta atcaacaaaa gcaaaatgtt gttgtcaata acctagctaa
    29641 tatggataca aatggatata aaagtaaaca acttttgact aaaagttttg atgaattaaa
    29701 gttggagggt tacaataact acgcaaatgg aactaaacaa aagcagatta taggcgatat
    29761 aagtccaggt atttctatgg atgaaactat cacaaatttt aatcaaggac ctataaaaac
    29821 tactgataat aaaatggatg tagctattca aggtaaggga ttttttctag ttagtgatgc
    29881 agctggaaat caattttaca ctagaaatgg gaacttcaga acagacaatc aaggtgacct
    29941 tataacaagt gaagggtatt atgtacttgg gacgaatact gctactggtg ctgtaggtca
    30001 tataaatgta ggaaatcaaa aatttgaagt ggcaaaagat aatacaatat cactagacgg
    30061 aaatgctatg tataaattta atattgtaga ttttaataac tacaataact taaaaaaaga
    30121 aggagataac ttatattctg gaggaggagc tatgaaagta aataatgcac ttacaataca
    30181 aagtgcgata gagtcctcta atgtagatat ggtatctgaa attaataata tgatgacaat
    30241 atcaagagaa tatgaggcaa atcaaaagat aattcaggct atggattcta aattagcaaa
    30301 aatagcaagt gagattggtt cagtaagata ggtaatagga ggtgaatttt tatgtacaca
    30361 atgttttata ctagtaaaac agctttatca gcaaatcaaa gtaaactaga tataatatct
    30421 aacaatatag caaattctga ttcaacagga tataaaaaaa taaatatgga atattctgat
    30481 ttagtggatg aagtactaaa tagaccatca tatcctacaa atggcaatga tatatcgact
    30541 ggaacaggag ctaaggcaac agctcccatg agaaattatg aacaaggtgc attggctcct
    30601 acagatagta agagtaattt ggcaatagat ggagaaggat tctttagagt gataagaaaa
    30661 gatggtacat atgcatatac aagaaatggt ggatttaatg tagatgcttt aggtaagatt
    30721 gtagatgata atggaaatat attagatgtc caatttgatg caggatataa ctataataat
    30781 acaaatatag atagtacaaa cctgacagtt tcaagaaatg gagagctatt cgtagataat
    30841 aaaaaaatag gaaaaatcaa cttatatcaa cctataggaa ctcaaaattt tatatctgaa
    30901 ggagatagtt tattcgtcgc aactgatgca gcacagatta aacaagttga gaaagtcgat
    30961 atagttcaag gctatagaga gaggtcaaat gtttctttac aagaagaatt tgttgactta
    31021 atagccactc aaagagcatt tcaaatgaac tcaaagggaa taaagacagc agatgaaatg
    31081 tggcaaatag cgaataattt aagagctaaa taattatgta aggtgaggaa tattcatgaa
    31141 tgatatgaaa gagtacgatt ttggcaaacc tcagagttat tcaagagaaa atttaacttg
    31201 tttaaatttt ttattagctg aattttgtaa aaaatataaa aactatataa tttatgaact
    31261 taagtgtaat tctagtatgg ttgttgatag tatagaccaa gtaaattatc agactttttt
    31321 agatagagta acttcttcat gcgtagtagt acaaaatgca atggaacctg ttatgaaaaa
    31381 cttttctttt agaatagata gaagtgtagc tgatatgtgg attgatataa cttctggagg
    31441 aactggagtt gtaaaggata atgatagaga acttacagaa cttgataaaa aagtgctttt
    31501 acaccttatg gatgatttag taagaaatat gcacttattt gagggttttg aaaatataca
    31561 agtattggat acacatacac atattaattt gccacaatta tgttctccaa ctgcaccagt
    31621 atgcgttgta gatttaaaag tgctaaatga taatgagtat attggaagtg tttctctttg
    31681 ctttccatac aatggtttag aggctctgtt agaaagtata tctgttatag aattttttga
    31741 taatgatgta ggagatgatt cagaggaatt tacccaaaaa atctataata gtgtatctaa
    31801 tatagaatta tcagttattg cagagatagg aaaagtatca attaatgttg aggatttact
    31861 caaactagaa gttggagatg taatagtaac aaataaaaaa ataaatgatt atatagatat
    31921 atttgtagaa aattcaaaat catacacagc aacaccagga tttatatcaa gtaaaaaagg
    31981 tgtaaaaata aatgatgctg ttggaaaaga ggtgtagtta tggacaatag taatcttatt
    32041 tcagatgaag aagcaaagat gttattaaat gataaagttg aaagtgaagt tgatggagat
    32101 gatgagttag ccttagatgt ctctgaagtt aatcgaaata atatacaaag gatacttgac
    32161 cttaagttag aattatctgt agttatagga agaactaaga tgactctaag agatatttta
    32221 aatttacata aaggttctct tattgaactg gatactttgg cagaccaaga tgtggaaata
    32281 ctaatagata ataaggtttt ggcttatgga aaagtagtgg tggtagattt aaattttggt
    32341 gtaaagataa caagtatagt aagtgaagaa gacatggtaa aatctcttgt ttagagataa
    32401 catcaattaa tacttaaggc atgaggtggt acttatttta aacttaaatg atataaaaaa
    32461 agatatacta aaactcaata aaaaagactc atgttctcta tataatgaat ctattaataa
    32521 tataaataat aattgtatat caactggatt aaaattttta aaacaagcaa gagatttaaa
    32581 cccagatgat gttgatatat taaatctcac aggtcttgta aacttactaa aatgtaattt
    32641 tgatgatgct gtagaaagtt tctataagag ttcactttgt gaaaaaactg ctctgtgtga
    32701 aaagtatata aacatgctta catctgagga gtttttaatt ttctttgaaa agtacaatca
    32761 acttataagg ttaataaata aaggaatgta taaagaagct atacaagggt ttaaacttat
    32821 aactgaccaa tactgtgatt taatagaacc ttatgagttg cttgccttac tgtatgacaa
    32881 ggaagaagaa tatataaaat ttgatgaatg tttagaagta ttgaagatta ttgataagga
    32941 aaattattta ttaaatcaag aaaataacac attatatatg tataatagtg ctaatataca
    33001 aactaaaagt aatataaaag tagatgatta taagaatgag ttcttacata aaagtagtag
    33061 taaccataaa attaatgatt ataatgatgt aactaaagaa aagagttcaa gcaaaaacca
    33121 gaaaagttca gattctaata agaaaaaaag tattaaaaaa aataagtacc tatatatagc
    33181 cataatatta ggaatattat tagtaggaca aagtatatat agttcttata agatgaataa
    33241 tttaactgat aaaatatcta aaaataatga aactaaaaat gaagagtcaa tagattctaa
    33301 cttgactaag aaagaaaata atatagaaga aaatgaagat atgagtaagg cttctaatat
    33361 aaataagagt aataaaaaca ttaataaaga ggatgatgta aaatctaaaa aaaatactgt
    33421 agaaaatgaa gatgataaag attctgactt atttacagag gatgaattga tgtctaaggc
    33481 gaatacttta aaatcagaaa agaaaactaa atcttctata caactatata agaaagttgc
    33541 agatataggt gaaaataaag ggaatacatc tgaagcaact tatcaagttg ctattctcag
    33601 tgaaaagtta aaagactata aaactgctga agaatattat aaaatgtatg tagaaaatta
    33661 ctcagaaaaa gatgcttatt ttgatgaatc ttattataat ttaagtatga tgtactataa
    33721 caatggtgat ttaaaaaatt ctaaattgac attaaagaag ttggttaata aggtaccaaa
    33781 tagtatgtat aataattcaa aagtaaaaga aattttaaaa gaagaatagt taaattagat
    33841 aagaaaaata aattatttta ttttaaaata atatgattat aatatattga cataccattt
    33901 taaaaaattt aaaatattaa ttataaaatg aggagggata aaaaatggaa tttgaaaaag
    33961 ggagtatttc aattcataca gaaaatattt ttcctataat taaaaaatgg ttatactctg
    34021 ataaagacat atttataaga gagcttataa gtaatggatg tgatgcagta agtaaacata
    34081 aaagacttgt atcactagga gaaatatcag aaaataagtc atcagattat aaaattacag
    34141 tatctgtaaa taaaggagaa ggtacactta aatttattga caatggaatt ggtatgactg
    34201 aagaagagat aaaaaaatac ataaatcaag ttgctttttc aggtgctgaa gatttcttta
    34261 ataaatataa ggataaaatg gaagagtcaa atgatataat aggtcatttt ggattaggat
    34321 tttattctgc atttatggtg tctaaaaagg tacaaataga tacactttca tatacagaag
    34381 gagcgactcc tgtaagatgg atatctgaag gtggtacaga atacgaaata tctgaatcag
    34441 atgctagaaa tgatagagga actactataa cactatttat tgatgatgat agtaaagaat
    34501 ttttagatga atttactgta agaggaataa taaataaata ctgttctttc ttaccagtag
    34561 aaatatattt agaagatgtt gaaagattag aaagagaagc taaagaagca gaagaaaaag
    34621 ctaaaaaaca aaaggaagat ggaaaagaag agattgtaga tgcaaaagta attgagcctt
    34681 taaacgacac taatcctcta tggttaaaat ctccaaaaga ctgtactgat gaggagtata
    34741 aagagtttta tagaaaggta ttcaatgtat ttgatgaacc tttattttgg atacatttaa
    34801 atgtagatta tcctttcaat ttaaagggta tactttactt ccctaaatta aaaaatgagt
    34861 ttgaactgac tgaaggaaaa gtaaaattat acaacaatca agtgtttgtg gctgacaata
    34921 taaaagaagt tataccagaa tttttacttt tattaaaagg agttatagac tgcccagact
    34981 taccattaaa tgtatcaaga agtttcttac aaaatgacag ggatgtaagc aaaatttcta
    35041 aacatataat taaaaaagta gctgataagt tgaaatctct ttgtaaaaat gaaagagaag
    35101 aatacaataa gttttgggat gatatacaaa tatttattaa atatggttgc ttaaaagatg
    35161 aaagtttcta tgagaaggta aaagaatgta tattattcaa aactattgat gatgagtata
    35221 taacattaca agattattta gaaaaatgta aggacaaaca tgaaaataag gtattttatg
    35281 taagtgataa ggaacagcaa tctcaataca ttaaactatt taaagaatac gacttaagtg
    35341 ctgttgtttt aaactcatca atagatactc attttatttc atttatggaa tataaagaga
    35401 atggagttaa gtttaataga atagatgcag acctttctga tgtattaaaa gataaaaatg
    35461 aaaataaaga tagtgaagaa aacaaagaag agatagctaa gatagaaggt ctgtttaaag
    35521 aagctgtcgg agaaagagtg aagaattatt ctgtagaagg attgaaaaat gaagacactc
    35581 cagctatggt attagtatca gaacaatcta ttagaatggc agaaatgcag tcaagatttg
    35641 ctggaatgga tttaggaatg aattttgagg aagaaaaaac tcttgtaata aatgagaaca
    35701 gtccaataat caaaaaattg gtttctctta aagatgatga ggaaaagaaa gataagatta
    35761 cgcttatttg taaccagata gcagatttag ctttactttc taataaagaa ttaaagccag
    35821 atgagttaga ttcatttgta caaagaagta ataagcttat gagtcttttg atagaattat
    35881 aagattgaat ttgaatacat tgaagcaaat ttataaaaag tattcaatat cagtgataag
    35941 aaagaagtgt ctcaaaatga acttttcagt tcatgaggcg ctttttttat gtgaaattaa
    36001 atttatttta atcatttcaa caatgaaaaa tatatttatc tctattttga gacagaccat
    36061 tctttatttt tttatctttg gttaatttta aatatttaag taggttctaa taaaaaactc
    36121 tatttagtta aatatagtta acttgatata taataagata atacatataa ttaagtaaaa
    36181 gattgttttt tagtttatgt ttaaatacat aattacactt tgttaaaaac ataaaattat
    36241 tactaaagta gaaataggag gttttagaat gaattttaat tataatttgc cagtaaatat
    36301 cttatttggg agaggcagaa ttaatgatgt gggaaaagaa gtatctaaat atggcaaaaa
    36361 agtattgata gtaacaggta aaaatagtac aaagaaaact ggattacttg ataaaacaat
    36421 agatttacta aaagactcta aaatagaata tgaagttttt gatagagtag aacaaaatcc
    36481 tcttataact actatatatt caggagtaga aattataaaa tcaactggat gtgattgtgt
    36541 tttaggtctt ggtggtggaa gcattatgga tgctgccaag agtatagctt tttcttataa
    36601 aaacccagga gatttaaatg attatatatt tggaattaga caaggtgaag aagctttacc
    36661 tataatctta gttccaacaa catcaggtac aggtagtgaa ggaaattgtt ttgcagtact
    36721 tacaaattca gaaactaaag ataaaaaatc tataaagaag aatagtatgt atgcaaaagc
    36781 atcaataatt gacccagaac ttatggttac aatgccaaaa catataattg catcagttgg
    36841 atttgatgca cttgcccata atatggaagc atatctttct aatggaagaa accctcttgc
    36901 agatgtacaa gctatttatg ggattgaact tatatcagaa aacctaataa aggtatataa
    36961 tgatgttaat gatttagaag catgggaaaa aataacactt gcaagtacta ttggaggaat
    37021 gacgattggt acagcgggta cagccttgcc acatggaatg gagcatcctg taagtggtct
    37081 tagagatgta atgcatggaa aaggacttgc agctttgact cctactatta tagaaagttc
    37141 atgggatagt gatattgaaa gatttggtaa tatttcaaag gtattaggag gaacttgtgc
    37201 agaagattgt tcagatgcaa ttagaaattt ccttaaaaaa atagatttag atataaaact
    37261 aagtgattta ggtattgaaa aatcagatat agattggtta actgataatt gtatgaaaat
    37321 atcagttgca aatattaaga gacatccaaa gtattttaat aaggaacaaa taaaggaaat
    37381 gtaccataag tctttataat ttgactttac atatttagtt ttatataaaa attataaatt
    37441 aataataaaa aattataagt aattaatagt aaaaaaattg tgtatagaag ttatatatat
    37501 aataaatttg tcttaagctt ttattttact ttctaataaa taaaggagtt taaaaaaggg
    37561 aagattaatt aagtaatatt ttataaaatt cttcgattta aaaactttaa gtagaggtga
    37621 aataaatgtt taatcccaaa agaataatat tcgaaaaagg aactttagac actgatgtgg
    37681 gtaaaaaaat atacaataaa tttagagata ataaagatgt agagataatt aatatatcat
    37741 caaataggat taaagaacat attccaggtg aaaatctata tgaacaatat agaagtggga
    37801 agcagactat ggtagttggg attagaaaaa gtctgaagtt tcaaacatgt aaaccttctg
    37861 ctaattatca actaccactt gtcagtggat gtatgggaag atgtgagtat tgttatttga
    37921 acacacaatt aggtgataaa ccatttataa gggtgtttgt aaatgtagat gaaatacttg
    37981 aacagacaaa aaaatatatt gaagatagaa agccacaggt aaccatattt gaaggggcag
    38041 ctacatcaga cccagttcca gtagagccat atactaattc tttaaagaaa acaatagagt
    38101 tttttggaag agaggaaaaa ggaagattta gatttgttac taaatacagt gatgtggata
    38161 gcttattgga tgctgaacat aataatcata cagaaatacg atttagtatc aatactccta
    38221 gaattataaa tgaacatgag cattatacag cctctgcaaa taaaagaata gagtcagctg
    38281 taaaacttgc tagggctggt tatcagattg gtttcataat agcacctgtg tttttatatg
    38341 aaggttggaa agaagagtat aaaaatctga ttataagtat aaaagaagct ttaccaaagg
    38401 attttgataa aaaaattata tttgaagtta tatctcatag atatacaact aaagcaaaaa
    38461 atagaatact agagatttat ccagatacac tattgccaat ggaaaatgag gatagaaagt
    38521 ttaaatacgg tcaatttgga tatggtaagt acgtgtatga taaagaacaa ttagatgata
    38581 tgaaagagtt ctttcttaag gaaataaatg gagtatttaa aaatagttta ataaaatata
    38641 taatatagca aatcttacct aaagatttgc tatattttat ttttatacat tttatgttta
    38701 taataaagca atgagattta gcactatcat ataagaaaat taaaaagggc actatctatc
    38761 aagaacattt tttctagttt tgatactata aaggataaga gtaacaaaaa tatcaggagg
    38821 agttatagta tgcatgcatg ggagtctatt caaattacat tggatttaat agaagcaaat
    38881 ttatcagaag aaatatcaat taatgaatta gcaaataaag caaatttatc accattttac
    38941 tatcaaagac tatttaaaag attggtaaat aagactgtaa tggagtatat aaagcttcgt
    39001 cgtcttgcaa gagcttctga atacttagca gaacataaga atcgtatact tgatgtagct
    39061 ttaaattttg gatttgctag tcatgagaca tttacacgtt cctttaaaaa agcatatgga
    39121 ttaactccag aaaaatatag agcaaatcca gtaaaactca atcactttat taagccagaa
    39181 ttaattttaa attatgctat ggttgatgaa ggtgttccac tgattgcaga tgatatagtg
    39241 attgaagtca atcgtaagac attgagtaat ccaaggacat ttgttggaat agaaatagaa
    39301 gtacctattt gccagttggt gggcggtgaa acaactggaa ttgcaatagt agaggaatta
    39361 tggatgaaac ttggaagtca aagacataat ataccaaatc aaattccagg tggaaatgaa
    39421 tttgctgctc tttatatggg aaatgcaaaa gaaggaaatt gtatgtatat ggcaggtgta
    39481 gaggtagagt caggtacatc agtagaagga tatagtactt ttgagttgcc agctaaagaa
    39541 tatttagtat gtggatttga ggcagaaaac tttaatgagt tagttaattc agctgttttt
    39601 aaagcagata aatttatgga aagatggatg aagaaacata atttaacaac tactgatttt
    39661 gcaattgaga tgtattaccc cactacacct gaagcagcat atctggaaca ttggattgtt
    39721 ccggttccta ttgaacaata gaaaggatga tgaatatgaa ttggcaagat gcgttttttc
    39781 aagatactaa acctacattt gagcaaatta atgaatttat taataatcca ttatgggaca
    39841 agttaaataa aactttggtt tctacttata atgtagaacc taagcttgaa tacagtaaat
    39901 gttcaatgca aagaggttgg aatgtaaaat ataaaaaaag aggtaaatca ctatgtactt
    39961 tatatccaca agaaggttat tttaaagctt tggttattgt aagtgaaagc aatagagtag
    40021 aggttgattt atttattaat acttgttgtg attatatcaa aaaaatatat aatgaggtaa
    40081 acttttttaa tggaagtaaa tggctaatga ttcaagtaga tagtttattg gtattaaacg
    40141 atatgcttga actaattaaa tttagagctt aacatataga acaggatgaa tatataagtc
    40201 atcctgtttt tatattcaat cagataaatt aatatatagt ctataatatg aataatttag
    40261 taaatttaaa tttactttat ctttctacat tctttgcaac taagtccaca tgtgtttttt
    40321 tcttgcatat tagtagcacc ccaattagca aattgttgta aaataggcac aatactttta
    40381 cctttacttg ttaatgtata ttcaactttt ggaggaattt cattatattg tttacgatga
    40441 acaataccag tagactctaa atcttttaat gattgagcta gcatagtatt tgtaatgcca
    40501 tccaattttc tttttatgct actatatcta attggatttt caactgctaa catacatata
    40561 ataggtaatt tccacttacc accgacaatg tctaatgcat aacggattgg acaggttaat
    40621 tcttcaacgt ttttagttat atttttttca gtatttatac tcattttaat tactccttag
    40681 ttatagtagt atctttttta tactttatca gaaaaaactg catacttgtt ttttctgtat
    40741 tttatattaa aattatatca aaggataatc cttaatacaa gtatttaaaa ggggtgtaag
    40801 aattatgaaa gcattagaat ttttgaacaa ggcacgagtt tattatttag caacagttga
    40861 tgagaacaat caagcacatg tgcgtccttt aggatttgtt atggaataca atggtaaact
    40921 tacattttgc acatctaatc aaaaggatat gtttaagcaa cttattttta atccaaaggt
    40981 tgaactttgt tgtatagacc aaaaccttaa tactctacgt attttaggtg aagcagtatt
    41041 tgttacatca aaagaaacac aagctaaggc acttgaaata atgccaagtt taggtcagat
    41101 gtactctgta ggagatggta agtttgaaat attctctatt gataaggcaa aagttagttg
    41161 ttgttcaatg agtggtaaaa agattgatgt agagctttaa ttataattga atcgacatcc
    41221 atagtgaaaa ttaagaaaac gttattactg aaatgttgat agatttaatt taaatgcaat
    41281 aaaaagattt ttaaataatg aatatgtaaa aatttttagt tattagatgt gtatttcaat
    41341 aatgatatac tattttgaat aattacatac tagaaataag ataattaaaa tttactttat
    41401 aatgggatag atttctttta aaaaatattt taactataat tgatttttat ttaatctgaa
    41461 aaaaatatta tgactataaa aaattgctac ttattatttg gatattttta
//
LOCUS       DAEPHU010000031        40743 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 01A10CD0081
            SAMN05941466-rid12468953.denovo.031, whole genome shotgun sequence.
ACCESSION   DAEPHU010000031 DAEPHU010000000
VERSION     DAEPHU010000031.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941466
            Sequence Read Archive: SRR6291087
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 40743)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 40743)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068158.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 22:43:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,892
            CDSs (total)                      :: 3,805
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 87
            rRNAs                             :: 8, 1, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 55
            CDSs (without protein)            :: 55
            Pseudo Genes (ambiguous residues) :: 0 of 55
            Pseudo Genes (frameshifted)       :: 21 of 55
            Pseudo Genes (incomplete)         :: 28 of 55
            Pseudo Genes (internal stop)      :: 16 of 55
            Pseudo Genes (multiple problems)  :: 8 of 55
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..40743
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941466-rid12468953.denovo.031"
                     /strain="01A10CD0081"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            complement(542..1381)
                     /locus_tag="KR231_001756"
     CDS             complement(542..1381)
                     /locus_tag="KR231_001756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HBH0004135.1"
                     /translation="MSDIKNEVSKKTLSKKDVIKSWLRWFFFAQSNYNYERLQSTAFS
                     HSMLPVLKKLYPDKEELKQEVETHLAFFNTEPICGCVIHGITIAMEEEKANGADEISG
                     DGMNAIKTGLMGPLAGIGDTLTQGVITPIVLAVCIGLTEGGASIAGPILFVIAQYIIM
                     TSISFGMWTNGYKYGKKAVESILQGGIVNKVIEGASILGTLVMGGLVGRFINLSTPIS
                     YTSGDFKFSLQTDLLDKIFPGLIPLVLTLLVLFALKKGLSPIKIMFILIVVGAITGIL
                     GLF"
     gene            complement(1405..2163)
                     /locus_tag="KR231_001757"
     CDS             complement(1405..2163)
                     /locus_tag="KR231_001757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBH0004136.1"
                     /translation="MHISLIQAVLIAIFYYLSWSPWLTYVGFFTWNRPLLAGFVTGII
                     LGDPVQGAIIGAGINMIYLGFISAGGAQMGDPAFAGYVGTALAIASKLDVSTAMAIAV
                     PLGTVATVLWIGKMTVNSFFAHWADREVQKGNVDRVAFINIVPPQILLFAMSFIPALL
                     VVYFGPNAIDGMLEVMNDNVLHVFNVIGAMLPALGIAMNLKLIGNKFTMPFFILGILM
                     AVYFKVDIIVISVIGVILALTITSIKYGKDSATS"
     gene            complement(2210..2683)
                     /locus_tag="KR231_001758"
     CDS             complement(2210..2683)
                     /locus_tag="KR231_001758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBH0004137.1"
                     /translation="MSNIALTRIDDRLIHGQVITAWCKITSAKRIVIVDDLVVKDPFI
                     VQVLQMAAPSTVKVEVHDVESGAEVLKSYNGDENLIVLVKYPKTVLGLVNSGVDLKEL
                     NVGGMGAGLGRKSFYKNISVSDEEKEIFRELISKDVKCFIQIVPDAKKIDVGTLL"
     gene            complement(2712..3128)
                     /locus_tag="KR231_001759"
     CDS             complement(2712..3128)
                     /locus_tag="KR231_001759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBH0004138.1"
                     /translation="MIHMAGIIIATHGNMAKAMLESAELIVGKQENVETLGLNHGDSI
                     DEFSRKLEDGIEKYKDEGVLVLLDFYGGTPFNTSAIIINKFAKVCELECLTGVNLPML
                     LELFLNRDTMKLKDLKNLCEEVGISGIKDVKTVLKL"
     gene            complement(3175..4227)
                     /locus_tag="KR231_001760"
     CDS             complement(3175..4227)
                     /locus_tag="KR231_001760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactitol-1-phosphate 5-dehydrogenase"
                     /protein_id="HBH0004139.1"
                     /translation="MKSVRFYGIRDTRVEDVDVPKILEKDDVIIKVKVAGICGSDISK
                     YSKTGPHMVGEILGHEFSGEVAQVGKEVRSFKIGDRVAVCPAMPCFECDECKKGLYSR
                     CNNVAIIGNKELGGCFAEYTKVKERNLIKIPDEISYETAAALEPVCIAGHGLFRSEAK
                     VGDTVVVLGTGPIGLFSIQWAKIFGSTKIIAVDVFDEKLDLAKELGADICINAKEKNI
                     VEEIKRLTDGDGADIVIESAGTPLTCGQVLLLAKKGGTVLYAGVPYGDVALTREQFEK
                     IVRSELTVKGTWFGNSFPFPGKEWSAGLYHMQKGDMNVEKLVTHRINLEEVPAYFEKV
                     YKRDIFFGKIMINIDN"
     gene            4623..5303
                     /locus_tag="KR231_001761"
     CDS             4623..5303
                     /locus_tag="KR231_001761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazolesuccinocarboxamide
                     synthase"
                     /protein_id="HBH0004140.1"
                     /translation="MKKVYQGKTKDVFELDNGNYLLKFKDDVTGKDGVFDPGENSVGL
                     SIDGIGRANLETSVKFFEILNNAGIKTHYVSANLEEATMEVLPAKVFGNGLEVICRYR
                     AVGSFLRRYGSCVEEGAKLDCYVEATLKDDDRCDPLITSEGLEALNIMTQAQFDSMKS
                     MTQKISNIVRDTIAEKGLELYDIKFEFGFYNDEVILIDEIASGNMRVYKDGVIVDPMD
                     LTALLLDK"
     gene            complement(5436..5756)
                     /gene="sugE"
                     /locus_tag="KR231_001762"
     CDS             complement(5436..5756)
                     /gene="sugE"
                     /locus_tag="KR231_001762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000118520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quaternary ammonium compound efflux SMR
                     transporter SugE"
                     /protein_id="HBH0004141.1"
                     /translation="MKWLFLFVAGLFEVFWAFQLKNSHGFSKLTPSILTVVGMIVSFY
                     FLSLALKHLPLGTSYAIWTGIGTVGTAIVGMAILNEPISISRIACIGFIVVGIVGLKL
                     LSTN"
     gene            6138..6965
                     /locus_tag="KR231_001763"
     CDS             6138..6965
                     /locus_tag="KR231_001763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbon-nitrogen hydrolase family protein"
                     /protein_id="HBH0004142.1"
                     /translation="MNFYKIAVCQMITTENKIENINHAVDMVTEAAINGSKIVVLPEM
                     FNCPYENKYFPKFAEEYPGETTTILSKLAEKHGIYLVSGSIPELEDGKIYNTCYVFDK
                     NGALIGKHRKMHLFDIEVTGKVSFKESDTLTAGNDVTVIDTEYGKVGIAICYDIRFPE
                     LSRLMALKGAEIVILPAAFNMTTGPAHWELSIRMRALDNQIFYVGAAPARNMNASYIA
                     FGNSRISDPWGRIIAQADEKECIIYADIDRDLIPDIRQQLPLLKHRRTDLYELNTLK"
     gene            7787..8461
                     /locus_tag="KR231_001764"
     CDS             7787..8461
                     /locus_tag="KR231_001764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBH0004143.1"
                     /translation="MNNKILVVDDEEGIITLLKDYFEMNGYEVYTAQSGKGALKKISK
                     NPDIILLDINMPEIDGIEVCNRIRDYVSCPILFLTARIENTDKINGFRAGADDYIVKP
                     FDLDELGARVSAHLRREKRKSNQTKIKFYNDLTIDYEKRLICIDNNQISLSKKEFDIV
                     ELLSMNPGQVFDKEKIYDRVWGYNSNGNSDVIMEHIRKIRIKLSKHTLENYIETVWGV
                     GYKWIK"
     gene            8449..9609
                     /locus_tag="KR231_001765"
     CDS             8449..9609
                     /locus_tag="KR231_001765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HBH0004144.1"
                     /translation="MDKINNMSLKKAFFVLTLSSLIIASTLTTFSYILLNNLYNSIQD
                     KYLKTPINTGFITIVQNNVNQFSDYDKTLLNIINILQLVLPLIFFIGLLLLADIIFYK
                     VKLKTPIEILNKGAMEISNNNLDFCLEYNNNDELGNLCNAFEKMRSELNKNNIKMWTM
                     INDRKQLNAAFSHDLRNPLTVLKGYSNYLTKYIPTGKLSDEKILSTTQLMSEHINRIE
                     YYVENMSNAQRLEDLVVSKSMSNINKFIENLDENISIIAKQEGKSFTLKSQINNINLF
                     FDENIILRVVENIISNAFRYARNNVSILIYLEQELLTFVIEDDGIGFSKESLKLALRP
                     FYRDKTLNDSNAHFGMGLYISKILCEKHGGSISIENNSTNSAKITAKFSTRN"
     gene            9880..10353
                     /locus_tag="KR231_001766"
     CDS             9880..10353
                     /locus_tag="KR231_001766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-alcohol phosphatidyltransferase family
                     protein"
                     /protein_id="HBH0004145.1"
                     /translation="MLSFTFCSLPFWICYFWCGISDIFDGLIARKLRQQSGIGAKLDS
                     IADFIFSVTILVTVGKNIALPMYLWWCIVAIALLRLISYSIGFFKYRTFSSLHTLMNK
                     ITGISIFAFPLLYICFGLDVAGIMICIVAFLSSFEEIAIMIKSKELNRDIKSIFM"
     gene            10639..11307
                     /locus_tag="KR231_001767"
     CDS             10639..11307
                     /locus_tag="KR231_001767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895525.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH0004146.1"
                     /translation="MIIKAKQLSKIYGSNNNKVIALNNVNLEINSGEFVSVIGPSGSG
                     KSTLLHILSGLDNPTSGQVLLDDKDIYKHTEKELSALRRKSFGFVFQQFNLLPVLTAS
                     ENISMPVLLDKKQPDKEYLNEISSLLGIADRLNHLPHELSGGQQQRVAIARALIAKPD
                     IIFADEPTGNLDSKSGSEVMNLLIKTSKQFGKTLVVITHDDRIAKLADRKISIIDGVL
                     MEVK"
     gene            11310..13778
                     /locus_tag="KR231_001768"
     CDS             11310..13778
                     /locus_tag="KR231_001768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBH0004147.1"
                     /translation="MKNYLSLSIKELKSQKLMTTFIIIAIVLSTIMTTVVGQSIGILQ
                     NLRIEQARSFNGDRHVSFHQLTKNQVDDIKKDDRVYQAGTSITLGSSKIKDSGISVLV
                     KEYDKTGLSNYPKLMKLKSGNLPKDKNEIALDENTLKLMGIKPRLGVTIPMNLDISLL
                     NDTIPPYNYTANFKLSGILEDDYTGYVSGIVNGIVGKGASENLLPKRYILSSLDFKIK
                     QQEKFQEIVNQLAKKINLSHNSIQYNWIYLNALKIQFEKDENSSNSDGISMIILVSLF
                     VALLVLLASGLVIYNILKISVTKKIKEYGCLRAIGAEPNQIYKIVILQILILCTIAIP
                     IGAVIGIISSKGITGMVTNILNPDILLANDNKEITELIHKNTTAYIFPLVLSTSISLI
                     FSLISALPSAIYASHVSPKIAMAGSTTKIKRKIKREKTIKNFERHLAWLNLKRNKGRT
                     IITILSLFMSITVFVALSEFSNVLDVSRSVSNLKEGDFSLTNEISGFDKSILDKIDKM
                     KNVNRTSFIKYSEYKQGEIDTDINFENSGEMLKIIGIDEQTLKDLMPSITDSILEDFK
                     NGSICFIKNPIAISTPGVKTRHTNLKPKDNITINKKQLDIYSTVDKMFFLQGNGWING
                     VDVIVYDSVYNTLTNKNKFNQINIYAKDKSKLEQIRLSIEQICENNPGSHWISYIESD
                     KQLKESFKQIEFLAWAVILFVGLIGTLNIINTTHTNINTRTNEIGVKRAIGMSNSSLY
                     KMFLWEGVYYGIFATIFGSIAGYVSAIIINMATIEKLDFTNIPITSILQATIISILAC
                     IIATLIPLRKVKKMNIIDCIDVNL"
     gene            complement(14017..15441)
                     /locus_tag="KR231_001769"
     CDS             complement(14017..15441)
                     /locus_tag="KR231_001769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBH0004148.1"
                     /translation="MKNQSLITQFRHTFIFIIIASIVATVITYVFALYLYIHSLNKDI
                     YPPNYYERQVPRIEKYINEKNITLLSQSNEEGLKRTIRGDDMLYQVVDNNGNILYGTN
                     PKKLFKTKEELFNNFINKTVRKGGYIHTVPIKGDNGKIEGAVILFYQVKITFANIRGR
                     FVFAVIIMALFSPFLYIVGFTRWLSKRFVKNINQPLHLLIDASKKIKEKDLDFEIDYY
                     SDNELGKLCSAFSEMKDELKGSLSAQWKMEQERVEMVEALAHDLKSPLSIILGYTDAL
                     IGNNTDDNEKLHRYLTVIRENTEKSAALVQKMQYTSDLEKSNIQLNLVPINLPEFLRQ
                     KVQDYELQAHQKEVELILKMQGNIQSPIQIDVDRLTRIFDNIISNSLQYTPSGGNISI
                     TVKDEKNCISYEICDSGRGFSSKDLKKALDKFYRGDEARQTKGGHSGLGLYIVKQLVE
                     QLGGSVKIENSKSGGACVKFWHSI"
     gene            complement(15460..16152)
                     /locus_tag="KR231_001770"
     CDS             complement(15460..16152)
                     /locus_tag="KR231_001770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBH0004149.1"
                     /translation="MSKILIIDDEMDLVMLLEDELKAKGHEVLIAYDGQAGIELSKQE
                     PDLIILDIMMPKMNGFEVCQAIRDDVLCPIIFLSAKQSETDKIKGLTFGGDDYVTKPF
                     GLRELMARIEANLRREKRSQYINEENKRSTLYFGKLCLYMKERAIKIDGKNIDLTKIE
                     YDIVELLALHAGQVFSREQIYEKVWGCDSEGDSSTVVERVKKIRAKFSAVTPEKEYIS
                     TVWGIGYKWNKM"
     gene            complement(16207..16983)
                     /locus_tag="KR231_001771"
     CDS             complement(16207..16983)
                     /locus_tag="KR231_001771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lantibiotic immunity ABC transporter MutG family
                     permease subunit"
                     /protein_id="HBH0004150.1"
                     /translation="MIKLLSSEWLRAKRTAVQWLTLFMPIIFSLCVVFYLTTKSGSTQ
                     EFAFEGFFTVWTVFIIPIGVGILAGFIVQEEELAGNFNGFLCVGISRVRLYLGKFLFL
                     LFCLTICTFIATLILCIGMSIAVPSGATIWLFLSAAGLVVIGTLPLLAIHLWVSFAWG
                     MGASIGISIGGILMAAILGLTSVGEKVWAFVPWTWPVKLGMLPGIYFIKEAGTISTEA
                     FYSKVMQTASIELIVVAIGLIIFLIGGVIWFKMWEGRKSY"
     gene            complement(16980..17750)
                     /locus_tag="KR231_001772"
     CDS             complement(16980..17750)
                     /locus_tag="KR231_001772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lantibiotic immunity ABC transporter MutE/EpiE
                     family permease subunit"
                     /protein_id="HBH0004151.1"
                     /translation="MNALQSELLKYKRTFMGKLIVFFPVSFAAYAFIMQSTLMQNPLS
                     QTTSWAWQSLLALIFNWWSFLFLPIGFALFATLVAFQEKKAGNYRALRTHNVSPMTLW
                     INKVIAMAVYSFISTLVLIVVTIITGLILKAGPVPFGQIIGASIVCWVVSLAILPLQL
                     WLATWKGMFLSMGVGALGMIFGVLAATKPFWIAVPWSWAVRMVCPIINIHPNGTILEA
                     GDPLLNTSVIPIGIVVSLVVFIVLTALTAAWFNRRDDK"
     gene            complement(17747..18451)
                     /locus_tag="KR231_001773"
     CDS             complement(17747..18451)
                     /locus_tag="KR231_001773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014466355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lantibiotic protection ABC transporter
                     ATP-binding protein"
                     /protein_id="HBH0004152.1"
                     /translation="MKDLILETKNLSKRYGEQMAVNNVSLQIERNSIYGLLGPNGAGK
                     STTLKMLVGLLRPTNGRIIFDRKPWKRESLAKIGSLIESPALYGNLTAEENLLVHTKI
                     LGIPKDKIYEVLEIVNLKNTGKKRASQFSMGMKQRLGIAIALLSDPELLILDEPTNGL
                     DPFGIQELRELIASFPKKGITVILSSHILSEVAQVVDNIGIINGGRLLFQGMPDPNEN
                     LEEFFTDVILKGGQNR"
     gene            complement(18706..19218)
                     /locus_tag="KR231_001774"
     CDS             complement(18706..19218)
                     /locus_tag="KR231_001774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0004153.1"
                     /translation="MKKISQEKISTHIQEVPQEKIEQWKSLYEKYKSILKVNSKSVLE
                     IIEFLKRKYVIVEETSEEFKHVVINNIKLNKPFSQKISSDKELKPIVFTIPNEGNAKK
                     LYDTQEEIYSGCKIIVGMEFETGYVFVEGSDELNDEITSFKGLDKYDINNYYLVANYI
                     RCLKKYKLID"
     gene            19544..19801
                     /locus_tag="KR231_001775"
     CDS             19544..19801
                     /locus_tag="KR231_001775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0004154.1"
                     /translation="MILNRAELFRGYSLNRFNEICNILSVNKIKYKYKVKNNAYSKKP
                     FFNEITLGNLGQKEDFSYEYLIYVHKDDYEQAESLINSKLR"
     gene            19944..20570
                     /locus_tag="KR231_001776"
     CDS             19944..20570
                     /locus_tag="KR231_001776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426324.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase family protein"
                     /protein_id="HBH0004155.1"
                     /translation="MKINIKSKLSEFIKQNNLFDDSRIISYLPNITIETDKIKTIMIN
                     EVVPTNTNDDFYSVDKDADYLKTTIPLFDSAGIKVSNINDILDMGIYITNAVKLPKSE
                     YTITRDTIKLHMPILEEEIKLFKNLEVVMLMGDVAKKSFNMITKKHIKKNVIPSISTY
                     KLRNNELYYDNLRVFPSYIMTGGNILIEKSKFEMASEDIKKMFEIING"
     gene            complement(20817..21596)
                     /locus_tag="KR231_001777"
     CDS             complement(20817..21596)
                     /locus_tag="KR231_001777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901940.1"
                     /note="N-terminal region resembles flavodoxins. C-terminal
                     ferrodoxin region binds two 4Fe-4S clusters; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EFR1 family ferrodoxin"
                     /protein_id="HBH0004156.1"
                     /translation="MNSKIYYFSGTGNSLVVSNILKETLNGSKEVIPLAIHRKENNID
                     INEDILVIVFPVYFADVPDIVKSFVEKLNFNINTHIYAIATCNGVAGHSLFTIDKLLK
                     KRGKKLSAGFLINMPGNALITPPDVEEERLKNQTNRVAEIAKCINNLEIGNIEGKNNL
                     KSHIDSVVLRLVGKNMQIATTKFFAENKCNRCGTCKRVCPVENISIVDKKPKWGNECE
                     RCLACFHWCPKEAINVKKSFLTNRKKYHHPDITVKDIFLDK"
     gene            complement(21664..22125)
                     /locus_tag="KR231_001778"
     CDS             complement(21664..22125)
                     /locus_tag="KR231_001778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HBH0004157.1"
                     /translation="MGGARDYLNGGKMKDFEKLYEATTKLVSTSLKVKDDLKKMFKQN
                     GYDITTDHYALLRFLWEQDGISQIDLCEKSCKDKSNTTRILDVMKNKGLIVRKVDVKD
                     RRKFQIFLTDLGRELEEPLNEIASIYATETFKSISDEELPLFTDILDRIGK"
     gene            complement(22101..22778)
                     /locus_tag="KR231_001779"
     CDS             complement(22101..22778)
                     /locus_tag="KR231_001779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin family protein"
                     /protein_id="HBH0004158.1"
                     /translation="MIITVINGSPRKNGATSKVLTYLYKDIERLIPDVKINYFDLSEV
                     NPSYCIGCLNCYKMGKCINQNDKVEYIHDIITKSDGVIFGSPTYGSSVTGLFKVFTDR
                     AHMMLERLLYRKPCIAVTTYENARGSKAISFIKSMVLDSGGYVCGSLSIKTGFNQNPI
                     TEKVESKIQKVSKKFIYCIEEKKNPPVLSQIYNFIAINAVLKPMAFKDIEQYKGIIDR
                     WEEQGII"
     gene            23011..23397
                     /locus_tag="KR231_001780"
     CDS             23011..23397
                     /locus_tag="KR231_001780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
                     /protein_id="HBH0004159.1"
                     /translation="MKKLPHISEAEYQVMKIIWKYAPISTTEVIEKLVETSTWSPKTI
                     QTMLLRLVKKGALTYEKNSRVFVYTPLVKEEEYVATESSSFLNRFYNGTLNSMVLNFL
                     ENDKLSEDDIEELREILNKRTTKGDK"
     gene            23400..25199
                     /locus_tag="KR231_001781"
     CDS             23400..25199
                     /locus_tag="KR231_001781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426313.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BlaR1 family beta-lactam sensor/signal
                     transducer"
                     /protein_id="HBH0004160.1"
                     /translation="MYAPFFIRFLLSTLTLSILIVVILLAKKVFKKHISAKYQYNIGF
                     ILLIMLIIPFVPLKYINLGNVFNYLYTFNQLGSSTNRTSMIKNSSNSVINNSNALNDF
                     SVSLNQVNFDSLNILLLISWIIGILIMIAITIHCNIKIKNMKKSIQILKDEEIVFIFE
                     KCKKDIGINKDFILCKSPIINTPITFGYFKPHIILPDKSISKLSLKDIKYILLHELQH
                     FKNKDILINYIMCFLQILYWFNPLVWYAFKEMRIDREIACDISVLKKLNKDSHIEYGQ
                     TLINFVDNISRPSNLTLTSDIGGSKKQIKKRLLKIMDFHNESNTLKFKSILIFTLIAL
                     IVFGNIPKLSIMADINEKYRPTNEQTVYEDLSQYFKGFDGSFVMYDLKSKQYHIYNKE
                     KSKTRISPNSTYKIYSALLGLENGIITRNNSHIPWDGKHHSNSSWNEDQDLFSAMENS
                     VNWYFQTLDKKTGLKNIQTYLRQIGYGNYDVSGGISNFWLESSLKISPIEQVELLESF
                     YTNKFKFEDKNIETVKDSLLISKKDGVSLFGKTGTANINGKDVNGWFIGYVEKNENTY
                     FFATNIQSKDYSNGSSASKITLSILNDKKIYNP"
     gene            complement(25554..27428)
                     /locus_tag="KR231_001782"
     CDS             complement(25554..27428)
                     /locus_tag="KR231_001782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HBH0004161.1"
                     /translation="MNKYNKIANELIKIIGEDNIISITHCATRLRVMVKDREIINDKK
                     VEKVDEVKGVFFTSGQYQIILGTGIVNKVYAEVEKMGLKTLSKKEQDELVKNNETGFK
                     KVMRTLADIFVPIIPVIAATGLFLGLKGCLFNDNVLGLFGMSSANIPLYIQTLVSVLT
                     ETAFAFLPAIIVWSAFKVFGGTPVIGLVIGLMLVSPILPNAYSVADPSNEIEAIMAFG
                     FIPIVGCQGSVLTAIVTAFIGANLEKWFRKHMPNVLDLIFTPFFVMLITMLVILLGVG
                     PIMHTIELKMVDIISLLIDLPLGIGGFIIGFTYPLAVITGLHHTYVMIETSLLANTGF
                     NALITLCAMYGFANIGTCLAFMKKSKNNQVKQTAVGAMLSQLFGISEPVLFGIQLRYN
                     LKPLIIMCASSGLGAAILSILHIQSNSYGLAVLPSYLMYIYDGYNLITYLLVSIFVVA
                     FCFIVTCLFGVPKEAINEDEDEELVFNENNENFVSPAKGKIVALENVPDETFSKKMLG
                     DGFAIDIIDGKIVSPISGKLETVVSSGHAFGIKGTNGEVLIHVGIDTVALNGDGFDVA
                     VKQGDMVKQGDVLVNVDLKRIHELGKSTLTMVLFPDGKKVNILDINKDVKIGQRICVE
                     "
     gene            complement(27433..29097)
                     /locus_tag="KR231_001783"
     CDS             complement(27433..29097)
                     /locus_tag="KR231_001783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glucosidase"
                     /protein_id="HBH0004162.1"
                     /translation="MEKKWWQKEIVYQIYPRSFQDSNNDGIGDLQGIISRLDYLKNLG
                     ITSLWLCPIFKSPMDDNGYDISDYLDIASEFGSMEDLKELIKESKDRGIKIILDLVLN
                     HTSDEHPWFQEALKNPESPYHDYYIFKKGNDLPNNWRSVFGGSVWEKVENRDEYYFHS
                     FGKKQPDLNWENPILRSELYQMINTWSQMGVAGFRVDAITFIKKNLSFQSLESDGVDG
                     LVKCTKTVRNQPGIEKMLYELKENTFKKYDCMTVAEAAGISYDQLGDFIGEDGFFSMV
                     FDFKHADLDVASGSEWFKRISWTIPDLRKCILDSQMYVQEHGWAANFIENHDQPRATT
                     KYLLQYERNDDAVKMLGAMYFFLRGTPFIYQGQELGMTNFKRDTINDFNDLSSIDQYY
                     RSIDESYSEEEALEFVNLRSRDNARTPFPWADKENAGFSDTTPWLKVIENYKDINAQS
                     QINNSESILEFYKKMIKLRQDSEYSDCLIYGSIEPIDIESDDIIAYRRQLDLVVIDCY
                     YNFSDKPVEIRVEEKYDIVFQNLDDINLLNKTVRLKPFHAVLLKVR"
     gene            complement(29111..29932)
                     /locus_tag="KR231_001784"
     CDS             complement(29111..29932)
                     /locus_tag="KR231_001784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HBH0004163.1"
                     /translation="MKLYKLLILDIDGTLRDEVYGIPESAKHAIRLCQKNHCSVVICT
                     GRSMGTIQDDVLSLGVDGYIAGGGNYIQYHGELLYNQSFNQRLIKEVVCLLKKREVAF
                     SIESQEKVFMNQKAKEIFETMNQLKGTNSCINKQHIQEKITYENNIEEYKSQDIHKIC
                     LWSNEKVFDEVKNILQDKMELAQRDISSQYYEIIQKDFHKGKAIKRLQERLGVTQKET
                     ICFGDGQNDVVMFQASDVTIAMKNSHQQLKDIATSICEDIFDNGIYKELKRRNII"
     gene            complement(30031..30795)
                     /locus_tag="KR231_001785"
     CDS             complement(30031..30795)
                     /locus_tag="KR231_001785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HBH0004164.1"
                     /translation="MKIEGLFNKYYNSFTANDKYICECILNHKEDCIKLSIDEFADKY
                     HISTSALSRFAQKLQLPGYSELRVIIRLNETEVEYKNQSKHQLMDCYNKVIDDIEKKD
                     CSIMFERMKKANRIIVFGEGYSQERVAKEMKRIFLPTGKIIYDVYGYDMIQALNHFIK
                     TDDMIFFISLNGDASTIIDFAKEMRMKGIYMVSITKMISNPLARLCDENLYIQSISIS
                     VDKQLDYDVTTPYFILIELLYIKYKMYLESEHIPRK"
     gene            complement(30792..31541)
                     /locus_tag="KR231_001786"
     CDS             complement(30792..31541)
                     /locus_tag="KR231_001786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HBH0004165.1"
                     /translation="MRLESLVNQNYDNLNENDKIIIKQILICQREYRNFSCEKIANEC
                     NVSRATLLRLCRKIGLDSFSDLKYLLKNNQLEFVNNDNNFHDVCENYRLLMNELQKIS
                     FQDICKIIYDAETIYIYGTGNEQKSLAQEIKRIFLSVGKCVIDLFDIGEIEFMRESFQ
                     KNDLFIIISLSGETKAGIEIAKFINNHIHTISLTRLDNNTIATLCEYNLYVETQKLDT
                     LQAISYEVVGAFYALLDLLHMNYIEYRRRKE"
     gene            complement(32045..32650)
                     /locus_tag="KR231_001787"
     CDS             complement(32045..32650)
                     /locus_tag="KR231_001787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HBH0004166.1"
                     /translation="MKIKENVLMLDSTRGSNCFIVFDKEIILIDTGLPFMGKNIIKEL
                     KTLGIKLTDIKHILLTHHDVDHISNIKLLKEKTGAKVWAHVEDIPFIIGEKDRPGFKK
                     FIGKAISRRLIKDVEPYGENMQIGNIKIIHTPGHTPGHVCMIFEAVLFAGDLVKNKNG
                     NIVPYPNPWNWDYKKMVKSIRELDNLKYEWICMSHGTPCIK"
     gene            32829..33467
                     /locus_tag="KR231_001788"
     CDS             32829..33467
                     /locus_tag="KR231_001788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBH0004167.1"
                     /translation="MSELSKRDKEKIQRENEIIDKAEKLFCLNGFDNTTMNELAKEVE
                     YTKRTIYKYFSCKEDLFFAVVLRGYKRLWDNVKIESAKGKTGFEKIKLSYFAFHKFYS
                     VEPSLLCLMGMIGIVNSEKSDTDMLFKEKFFSFNKFMFDEIQGMFEIGKNDRSIRHDI
                     EIPTLMYSSIFTLTGFFNLLSVTGKSYLNNFNIDEEKFIETTLALLIDSIKA"
     gene            33599..34261
                     /locus_tag="KR231_001789"
     CDS             33599..34261
                     /locus_tag="KR231_001789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBH0004168.1"
                     /translation="MAKILLLEDDDTITFGIKTSLEKKNHTVCCYNTIAEAKKNFDKT
                     IDLILLDLNLPDGIGYEFCQYVKSIEDTPVIFLTVRDDEKDIIRGLDMGADDYVVKPF
                     LLSVLQSRINAVLRRTHSNTNNTITCENISLNKVEVKAYLDNVEVPLTAGEYKLLLSL
                     MENKNRAMTRTKLLEMLWDVDGNFVNDNTLTVTIKRLREKLKNPPCIKTLRGIGYRME
                     DS"
     gene            34261..35442
                     /locus_tag="KR231_001790"
     CDS             34261..35442
                     /locus_tag="KR231_001790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBH0004169.1"
                     /translation="MKTPRNINSTVVFIIFCLIVTFLLSVILTTITSFNEYNVLSKAL
                     GASYEYNPKSTESILKSLKNSSDKDFKTGNEILSKHGYSKSTFWSKNFFYFLVISFGI
                     ISTMATVIYIIKHRTNKQKLSRINNLTQYLEEVNLGKESVLLRCEDEFSHLEDEIYKT
                     VGELRCSKEFALKERQTLSDNLADIAHQLKTPITSMSLMAQLLSENCPDEEIDYINRL
                     TNQISRLERLVSSLLTLSKLDASTLIFESKLIDVHSLLTYAIEPIEGSLREKHQTFTI
                     EASPSVEFEIDINWTLEALLNILKNCSEHIEDGGYIVAYYSQNPLYVEIIIEDNGKGF
                     AQEELPYIFNRFYRGKNASKDSIGIGLALSKSIIERQNGTLHAENCHNGGARFIIKFY
                     T"
     gene            complement(35623..38283)
                     /locus_tag="KR231_001791"
     CDS             complement(35623..38283)
                     /locus_tag="KR231_001791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBH0004170.1"
                     /translation="MNILQEYTLDFVRRNKRSSIAIMLAILLTTTMMSSLCGLLYTMW
                     TDFIRLSIEKEGNWHGELFDYTYGSDLPLIENFSSVDDVMVKGQWYVGKINDEKRDYI
                     IYRNATSEYWNSMPEKDTIIEGRRPNNANEIALSKQYFENNPSVKIGDKITLPIGYRI
                     LNGKPLEPIAPKSKGESFKKISEATLTIVGKVDVSTSSVIPAYTALGYLDKTSIKPND
                     SITVYLRFKNIRDTYKELPKLAKSLGWKTNEYGKYNLKYNSNYLLKMLVFSPEQKASM
                     SSISKFSTPIMYLTIAIFTVAVFVMVIYNAFSLSANARLTQLGILSSVGASPKQIKRS
                     VVFEGFLLTIIPLPIGLFLGWLLCNRLIVYVNSVNYHTDVPEVVFTYGIPAFLPAVLL
                     TIVTVWISALIPARKVSKISPIEAIRQGDSVKIKKSHKYSLGKIFGIEGELASNALRA
                     RKKSYRTATISLTLSFLLLTCFLHIIANQEGAKAVYGSDNYKDQRDIAVYLENSEPIE
                     SAFIEKLDNTEGVKSSLYYQKMSASTWLTEKDASKELAKNGGFKSIVSSKKYSPIERD
                     GKFRIISNIIGLDDKSFTEYCRQISVDPKLFYNTKNPTSIVYNKEEDINRSTRRNKVY
                     IDYLNLSIGDNIKLNEKVYDEDKGDYTYNMKVGAITSTLPKIVDTSSKYTLMQIVPMS
                     MVQEISKNYDEVSRLRSNRLIGVFKVNNREDIPRVREKLESIYNKDYGSGDYSIEDVL
                     ESEKQKASGIKTMNLIVGFITGLLAMIGLSNVLATVSGNIRSRRQEFAMLRSVGLSPE
                     GIKKMLILEGLFLGITPLLLSIPVQIGIVYAFLRINEIYFIEYLPFAPISTIIGFTIL
                     ILFIVIASYMTGYKQLKNENIVESIKNETI"
     gene            complement(38280..38963)
                     /locus_tag="KR231_001792"
     CDS             complement(38280..38963)
                     /locus_tag="KR231_001792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH0004171.1"
                     /translation="MEILKCENLTKIYGSNQTRVTALNNVNLSVQKGDFVSIVGASGS
                     GKSTLLHLLGGVDRPTSGKIYVEDTEISSLKEEALAVFRRRKVGLIYQFYNLIPTLDV
                     RKNILLPMLLDKRKVDEDRFSEIVSILGLSDRLNHLPSQLSGGQQQRVSIARSLIYRP
                     AILLADEPTGNLDRKNSEEIVDLLNLSNKRFNQTILLITHDEKIALEANRIVTMEDGV
                     IVSEKVVKK"
     gene            complement(39307..40260)
                     /gene="blaCDD"
                     /locus_tag="KR231_001793"
     CDS             complement(39307..40260)
                     /gene="blaCDD"
                     /locus_tag="KR231_001793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434692.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDD family class D beta-lactamase"
                     /protein_id="HBH0004172.1"
                     /translation="MKRKKNFIWIAILLVGVVMVMYYVGKKHNDINQKTDKNYIKSEL
                     NKSELNKSKIENNDKNKKEKINMVDYSDCFEGISGGAIFYNTKNKEYNIYNKELIETR
                     RSPCSTFKIVSTLIGLEKGVINSKESVMGYDGTEYPNKNWNKNLSLEEAFKESCVWYY
                     KKLIDKVDAKSVQNILDDLKYGNCDISEWEGDLKNGKGHLNGFWLESSLQISPKEQVQ
                     TMAKIFEGDTNFKKEHINILRDIMKIDINDKNINVYGKTGTGFDEKNKRVDAWFVGML
                     EREGDTYYFAIKSDDSNKEITGPKVKEIAINIIKKYYSVRE"
BASE COUNT        14380 a         6611 c         4959 g        14793 t
ORIGIN      
        1 accaccttag attatcttta tctattaata ttaacaaaaa gtattaattt ttacactatt
       61 tttgattatt tgttttataa ttatcaaact caatttagcg ttaaagcata ataaatttta
      121 ataaataatg caaaaattta agaataagca tttaaaatat atgtcacagg aagtttacaa
      181 ctattattta taatacatta gttacatatt ataatatctc gacaatgtct taacaatatc
      241 tcgattatat attttaatat ataactaata tgttataata ttttaattaa attaaataaa
      301 tttatatttt tttgaaatca cttaatattt tatataaaaa tgaaaaagca cctcattctg
      361 attaaaaatc tttctgagat actttttaaa atattaaata ctacatatag cttacataag
      421 tttaaaattt aatctattat aaaattaccc taattgccaa actttttaat ataaattttc
      481 caacatccta caaatataat caatagatat agaatcctaa cttacaccaa tatatattta
      541 tttaaaatag tcctaaaata cctgtaatag ctcccactac tatcagtata aacattattt
      601 ttattggaga aagacctttt tttaaagcaa agagtactaa taaagtaagt accaaaggaa
      661 ttaacccagg aaatatctta tcgagtaaat ccgtttgaag actaaattta aaatcaccac
      721 tagtataact tattggtgta gataaattaa taaacctacc tacaagtccc cccatgacta
      781 aggtacctag tatagaagcc ccttctataa ccttatttac tattccacct tgaagtatac
      841 tttcaacggc ttttttccca tacttatatc catttgtcca cattccaaaa gaaattgaag
      901 tcattattat atattgagct attacaaata atataggtcc tgcaattgat gctcctccct
      961 cagttaaacc aatacaaaca gccaacacta taggagttat aactccttga gttaaagtat
     1021 cgccaattcc cgctagtgga cccatcaagc ctgttttgat agcattcata ccatctccac
     1081 ttatttcatc tgctccatta gctttttctt cttccatagc tattgttatt ccatgtataa
     1141 cacatccaca tataggttct gtgttaaaaa atgctagatg agtctccact tcttgtttta
     1201 actcttcctt atctggatat aattttttaa gtactggcaa cattgaatgt gaaaaagctg
     1261 ttgattgcaa tctttcataa ttgtaattag attgtgcaaa gaaaaaccat cttaaccatg
     1321 attttattac atctttcttg cttaacgttt tcttagatac ttcatttttt atatctgaca
     1381 taatattttc cccctcacat gtatttaaga tgtagcacta tcttttccgt acttaattga
     1441 agtaattgta agagcaagta ttactccaat aacagatatt actattatat ctactttaaa
     1501 ataaacagcc attagtattc ctaatatgaa aaagggcata gtaaacttgt ttccaatcaa
     1561 ttttaaattc atagcaatcc caagtgctgg caacatagcc ccaattacat taaatacatg
     1621 taacacatta tcattcatta cttccaacat accatctatc gcatttggac caaaataaac
     1681 aactaataat gctggtataa aactcattgc aaataacagt atctgtggtg gtactatatt
     1741 tataaatgct actctatcaa cattcccttt ttgaacctct ctatcagccc aatgtgcaaa
     1801 aaaagaattt actgtcatct ttccaatcca aagtacagtt gcaacagttc ccaatggtac
     1861 agctattgcc attgcagtac ttacatctag cttagatgct atagctaaag cagtacctac
     1921 atatcctgca aaagctgggt cccccatctg agctccccct gctgatataa aacctagata
     1981 tatcatattt atacctgctc ctataattgc tccttgaaca gggtctccta atataattcc
     2041 cgttacaaat ccagccaata gaggtctatt ccatgtaaaa aatccaacat aagtcaacca
     2101 cggactccaa gaaagataat aaaaaattgc tattaatact gcttgaatta gtgaaatgtg
     2161 catattcttc ctccctattt tcttttaaag atttacaaga tagtcttctt tacaataatg
     2221 ttcctacatc aattttcttt gcatctggta ctatttgtat aaagcattta acatcttttg
     2281 atattagctc tctaaatatt tctttttctt catctgacac agatatattt ttataaaaac
     2341 tttttctacc aagccctgct cccatacctc caacattcaa ttcctttaaa tctaccccgc
     2401 tatttactaa acctaagaca gttttagggt atttgaccaa tactattaaa ttttcatctc
     2461 cattatatga ttttaagact tcagcacctg attctacatc atgtacttca accttaacag
     2521 ttgatggagc tgccatttgt aaaacttgaa ctataaatgg gtcctttact actaaatcat
     2581 ccacgattac tatccttttt gctgatgtaa tcttacacca agcagtaata acttgcccat
     2641 gtattaatct atcatcaatt cttgttaatg ctatattact cataattatt cctccagatt
     2701 tttaatttat tttacaactt taaaacagtt ttaacatctt tgattcctga tatcccaact
     2761 tcctcacata aattcttcaa gtcttttaac ttcatagtat ctctgtttaa aaataactct
     2821 aaaagcatag gtaaatttac acctgtcaaa cattctaact cacatacctt agcaaattta
     2881 tttattataa tagcagatgt attaaatgga gttccgccat aaaaatcaag caatactaaa
     2941 accccttcat ccttatattt ctcaattcca tcttctaact ttctactaaa ctcatctatg
     3001 ctgtcaccat ggtttaatcc taaagtttct acattttcct gtttgcctac tattaattca
     3061 gcactttcta acattgcttt agccatattt ccatgtgtgg ctataattat tcctgccata
     3121 tgaatcatac ctttcttaac cttttttata tggattatta tttagtactc taatctaatt
     3181 atctatatta atcattatct taccaaagaa aatatccctt ttgtatactt tttcaaaata
     3241 agctggtact tcttctaaat ttattctatg tgttactaat ttttcaacat tcatgtcacc
     3301 cttttgcata tgatacaatc cagcactcca ttcttttcct gggaatggaa aggagtttcc
     3361 aaaccaagtt ccctttacag ttaattcact tcttactatc ttttcaaatt gctctctagt
     3421 caaagctaca tccccatatg gtacacctgc atacaatact gtacctccct ttttagctag
     3481 caacagtact tgaccacatg tcagtggagt accagccgat tcaataacaa tatctgcacc
     3541 atctccatca gttaaccttt ttatttcttc tacaatattc ttttcttttg catttataca
     3601 aatatctgcc cctaactctt ttgccaagtc taacttctca tcaaatacat ccacagctat
     3661 tatttttgta gaaccaaata tttttgccca ttgtattgaa aataatccta ttggacctgt
     3721 accaagtact acaacagtat ctccaacttt agcttctgac ctaaaaagac catgtcctgc
     3781 tatacatact ggttctagcg cagcggcagt ctcataactt atctcatctg gtatttttat
     3841 taaatttctc tctttcacct ttgtatactc tgcaaaacaa cctccaagtt ctttatttcc
     3901 tattattgct acattattac atcttgaata caagcctttt ttacattcat cacattcaaa
     3961 acatggcata gctggacaaa cagcaactct atctcctatt ttaaaactcc ttacttcttt
     4021 accaacctgt gccacttctc cagaaaattc atgccctaaa atttctccaa ccatatgtgg
     4081 acctgtcttt gaatattttg atatatcaga accacatatt ccagctactt ttactttaat
     4141 tattacatca tctttttcta atatttttgg tacatccaca tcctccactc ttgtgtctct
     4201 tataccatag aatctaactg acttcactat taaccacccc tactttttat ttgagaatat
     4261 atccctattg tttatatgtt aaatatctaa agcaactttc atgccaatat atgtaagcat
     4321 tgtattcatg cattttataa aattatcatt aaatgtgtgt caaagtgtgt caaaagtttc
     4381 ttatattaaa acttatgtgt gtcaatataa acgacactaa cattttatat tagttctctt
     4441 attataagtt ttataaaatg tacttttttt gttattttta taaaattgtt cggaaatttc
     4501 ccttctattt gtgatataat attaaatata aggtatcaat ataaattttc atgcgaatat
     4561 cagaactttt ttgacactaa tgccttattc aatataataa tttaactttt tggaggttgt
     4621 ttatgaaaaa agtgtatcaa ggaaagacta aagatgtttt tgaattagat aatggaaatt
     4681 acttacttaa atttaaagac gatgtaactg gtaaagatgg agtatttgac ccaggcgaaa
     4741 atagtgtagg tctaagtata gatggaattg gtagagctaa tttagagaca tctgttaagt
     4801 tctttgaaat tctaaacaat gctggaatta aaactcatta tgtaagtgct aatttagaag
     4861 aagcaactat ggaagttcta ccagcaaaag tttttggtaa tggattagaa gttatttgtc
     4921 gttatagagc tgttggtagt ttcttacgtc gttatggttc atgtgttgaa gaaggtgcta
     4981 aactagattg ttacgtagaa gcaactttaa aagatgatga ccgttgtgac cctcttataa
     5041 catctgaagg tttagaagct ttaaacatta tgactcaagc tcaatttgat tcaatgaaaa
     5101 gcatgactca aaaaatttct aacatagttc gcgatactat agctgaaaaa ggtcttgagc
     5161 tttatgatat taaatttgaa tttggattct acaatgatga agtaatctta atagatgaaa
     5221 tagcatctgg aaatatgcgt gtttataaag atggtgtaat agttgaccct atggatttaa
     5281 ctgctctttt attagataaa tagtatatac atataattta caaatataat aaacttataa
     5341 ataagataag ctatgaagta aagacttttt aaatgttgat tatttttaaa cattttctcg
     5401 cctttaattt catagcttat ttaaattaat atactctaat tagtagataa tagctttaac
     5461 cctacaattc ccaccacaat aaaacctata catgcaattc ttgatatact aataggctca
     5521 tttaaaatag ccatgcctac aatagctgta ccgacggtac caattccagt ccatattgca
     5581 tatgaagttc caagtggaag atgttttagt gctaatgaca aaaaataaaa acttacaatc
     5641 attccaacaa cagtaagtat acttggagtt aatttagaaa atccatgtga attttttagt
     5701 tgaaaagccc aaaacacttc aaacaaacct gcaacaaaca aaaataacca tttcataaat
     5761 tcatccctct tttcaaatat gtctcttatt tttccaataa aataacctga gaaatattat
     5821 aaaatatctc ccaggttttt gtccttccgt gttcacaaca aaaactatgt tgtgggtttt
     5881 atctcggacc agaccaatca ttaataattg cggaacccta taaaactcta ttaattattc
     5941 tattttatct ataataatac tatcaacata tataaaaaaa gtcaatatat gggttccata
     6001 tataataaaa ataactttta tatacctttt aatattctta ttcacttctc tccataccca
     6061 tttgggtcaa tctaagaata tctaattttt atttaatatg ttataataac ataaaaatat
     6121 tgaaaggagt aatttctatg aatttctata aaattgcagt atgtcagatg attactacag
     6181 aaaataaaat tgaaaatatc aatcatgctg tagatatggt aacagaagct gccatcaatg
     6241 gatctaaaat tgtagttttg ccagaaatgt ttaactgtcc atatgaaaat aaatattttc
     6301 ctaaatttgc tgaagaatat ccaggtgaaa caacaacaat attgagtaaa ttagctgaga
     6361 aacatggaat ttatctagtt tctggtagta ttcctgagtt agaagatgga aaaatctata
     6421 atacttgcta tgtatttgat aaaaatggag ctctaattgg aaaacatcgt aaaatgcact
     6481 tatttgacat tgaagttaca ggaaaagtta gttttaaaga atcagatact cttacagctg
     6541 gaaatgatgt tactgtaata gataccgaat atggaaaagt tggtatagct atttgttatg
     6601 atattcgttt ccctgagtta tcacgtttaa tggctcttaa aggtgctgaa atcgttatct
     6661 tgcctgctgc atttaatatg actactggtc ccgcccattg ggagttatct ataagaatgc
     6721 gtgctttaga taatcagata ttctatgttg gtgctgcacc tgctagaaat atgaatgctt
     6781 cctacatagc ttttggaaat tcaagaattt cagacccttg gggaagaata attgctcaag
     6841 ctgatgaaaa agaatgtatt atttatgctg acattgatag agatttaatt cctgacataa
     6901 gacaacagtt accacttctt aagcacagaa gaactgattt atatgaactt aatactttga
     6961 aataaaacag aacataaccc cataaatcat aaattaagtg ttaaaaaaat ttatggggtt
     7021 ctcattaatt tgatttaaaa ttaatttcat aaaaataata ctaatattaa tttaattaaa
     7081 taatactaat aattactaat gattatgcta attatcagca tttactaatt taatcactat
     7141 tagttatttc ttttattaaa tatctttact ttttttactt attatgtctt ctagctttac
     7201 atttggatta tagtatttct ttctattttt agtcacatct ttctattgaa ttacttgctt
     7261 aaaacaccaa tgcacacatt ccagacaatg ttcacaatta tgtaaaaatc ttgctctacc
     7321 ttcttcaatg ttgatattat ctctcctagt tgatattatc tttcctaaaa tttcttttaa
     7381 ttaaaaaaca acattcgttg atatatcgag tatattttaa gcaactgaaa aaaacaataa
     7441 taattgatat atcaactaat taatgtagat taattcattt ttataattta tatacttttt
     7501 aattaatcta cctttttaat taaaattctt cctttctatt tatccatttt aaacttaaat
     7561 tataagattt catcagctgt gtttttgcat tccaataagt attaaatatc aaatatatat
     7621 tctattaaaa tttctaataa tttcatcctt gatttattta atatataaaa atatactaac
     7681 tttaatgatt aagttttgaa atataactaa gaatttgaga ttttattgag atttttatac
     7741 taaagtatac atactataca agcttaattt agaagggagc attcttatga acaataaaat
     7801 actcgtcgta gatgatgagg aaggtataat aacactctta aaagattact ttgaaatgaa
     7861 tggttatgag gtttacactg ctcaaagtgg aaaaggcgca ttaaaaaaaa tatccaaaaa
     7921 tccagatatt attctacttg atataaacat gcctgaaata gatggaattg aagtttgtaa
     7981 tagaattaga gattatgtat catgccctat tctatttctt acagctagaa ttgaaaatac
     8041 tgacaagata aatggttttc gtgctggtgc tgatgattat attgtaaaac cttttgattt
     8101 agacgaactt ggagctagag tatctgctca tttaagacgt gaaaaaagga agtcaaatca
     8161 aactaaaatt aaattttata atgatttaac gatagattac gaaaaaaggt taatttgtat
     8221 agataataat cagatttcac tttcaaaaaa ggaatttgat atagtagaac ttctctctat
     8281 gaatcctgga caagtatttg ataaagaaaa aatctatgat agagtctggg gatacaatag
     8341 caatggaaat agtgatgtta taatggaaca cattagaaag atacgaatca aactatcaaa
     8401 acatactctg gaaaattata tagaaacagt ctggggagtt ggttataaat ggataaaata
     8461 aataatatgt cattaaaaaa agctttcttt gttcttactt tatcttcact aattatagca
     8521 tcaacactta ctactttctc atacattttg cttaataatc tatataattc tatacaagat
     8581 aagtatttaa aaacacctat aaatacgggt tttataacca tagttcaaaa caatgtgaac
     8641 caatttagtg attatgataa aacgttactt aatataatca acatacttca gcttgtactt
     8701 ccacttatat tttttatagg acttttatta ttagctgata taatttttta caaggtaaaa
     8761 ttaaaaacac ccatagaaat actcaataaa ggtgcaatgg aaatatccaa caacaattta
     8821 gacttttgct tagagtataa taataatgat gaattaggta atctatgtaa tgcttttgaa
     8881 aaaatgaggt ctgaactaaa taaaaacaac ataaagatgt ggactatgat taatgataga
     8941 aaacaactta atgctgcttt ttctcatgat ttaagaaatc ccctaacagt tctaaaaggt
     9001 tactcaaact atttaacaaa atacatacca acaggtaagc ttagtgatga gaagatttta
     9061 tcaaccacac aacttatgtc tgagcatatt aacagaattg aatactatgt agaaaatatg
     9121 agtaatgctc aacgattaga agatttagtt gtttcaaaat ctatgtcgaa tataaacaag
     9181 tttatagaaa acttagatga aaatatatct atcattgcta aacaagaagg aaaatctttt
     9241 acacttaaaa gtcaaataaa taatataaat ctattttttg atgaaaatat cattcttaga
     9301 gtcgtcgaaa atataatatc gaatgctttt agatatgcta gaaataatgt atccatactt
     9361 atatatcttg aacaagaact ccttaccttt gtaattgaag atgatggtat aggatttagt
     9421 aaggaatctc taaaattagc tttaagacct ttctatagag ataagacttt aaatgacagc
     9481 aatgcacact ttggtatggg tctttatatc tcaaaaatat tatgtgaaaa acatggtggc
     9541 tctatttcta ttgaaaataa ttctactaac agtgctaaaa ttactgctaa attctcaaca
     9601 agaaattaaa atgattttgt aagctttcac tgctattata taaaatttgt tagtttagaa
     9661 tttataaaat gtatttcaat ttataaccaa tatatatact attttgtaga aattgtaaga
     9721 gttgcttcaa ttataatatt ttggcaaaag gcatttgaaa caataataga aatatatatt
     9781 taaatatgta gaatagtatg aaattagaat tttggaggtg attatattaa aagttttgct
     9841 aataatatta cattctctcg tattgtgttt gcattgctaa tgcttagttt tacattctgt
     9901 tcactgcctt tctggatatg ttatttttgg tgtggaatta gtgatatatt tgatggtctt
     9961 attgcccgaa agttgagaca acaaagtgga ataggtgcaa agttagatag tattgctgat
    10021 ttcatttttt cggttacaat tttggttact gtcggaaaaa atattgctct tcccatgtat
    10081 ctatggtggt gtattgttgc aatagcattg ttacggttga ttagttacag tattggtttt
    10141 tttaagtatc gcacattttc atcgcttcat actttgatga ataaaatcac tggaatttct
    10201 atctttgcgt ttccattact ctatatttgc tttggtcttg atgttgcagg aattatgata
    10261 tgtatcgtgg cttttctttc ttcttttgaa gaaatagcaa ttatgataaa atcaaaagaa
    10321 ttaaatcgtg atataaaaag tatatttatg tgaaaactta gaatttgtga caaaaataat
    10381 ttatataata atgaggaagt aaaacataaa aaattatcca caagtttatg tgtaaaatag
    10441 ttttaaagca atagagttgt attgtaaagc ctttagtgca taaattacat tttaaattaa
    10501 aaatgatact gaaactgctt atcagcactg cgaattatcc gcaaatagtg aagacttttt
    10561 agatttaagc taaaagttgg gaaaaaattg agttttaaaa cttacactct tcttatatag
    10621 aaaaggagag tgttttttat gattataaaa gcaaaacaat tatcaaaaat atatggttct
    10681 aataacaata aagttatcgc acttaataat gtaaatttag aaataaactc aggtgaattt
    10741 gtttctgtaa ttggaccttc tggaagtgga aaaagcacac ttttacatat tttaagtgga
    10801 ttagataatc ctacctctgg acaagtgtta cttgatgata aagatatata taaacacact
    10861 gaaaaagaac tatctgcact tagaagaaaa tcctttggat tcgtctttca acaatttaat
    10921 cttttacctg ttctgacagc atctgaaaat atttcaatgc ctgtacttct agataaaaaa
    10981 caacctgata aagaatattt aaatgaaatc tcatcattac ttggaattgc agatagactc
    11041 aatcatcttc cccatgaact ttcaggtggt caacaacaaa gagttgcaat tgctagagca
    11101 cttattgcaa aaccagatat aatatttgct gatgagccta caggaaactt ggacagtaaa
    11161 agtggcagtg aagttatgaa tcttcttata aaaacttcaa aacagtttgg aaagacttta
    11221 gtggtaatta ctcatgatga tagaattgca aaacttgctg atagaaaaat ttcaattatt
    11281 gatggtgttc ttatggaggt gaaatagaaa tgaagaatta cctttcactt tcaataaaag
    11341 aattaaaaag ccagaaactt atgactacat tcatcattat agcaatagta ctatcaacta
    11401 ttatgacaac tgtggttgga cagtcaattg gtatcctaca aaatttaaga attgaacaag
    11461 cccgttcttt taacggtgat agacatgtat cctttcacca acttactaaa aatcaagttg
    11521 atgacataaa gaaagatgat agagtttatc aagctggtac ttcaataact cttggcagta
    11581 gtaaaataaa ggattctggt atctctgtac ttgtaaaaga gtatgataaa acaggacttt
    11641 ccaactaccc caaattaatg aaattaaaat ctggaaattt gcctaaagat aaaaacgaaa
    11701 tagccttaga tgaaaacaca ctaaagctta tgggtataaa accaagacta ggagtgacta
    11761 tacctatgaa tttagatatt tcacttttaa atgatacaat accaccatat aattacacag
    11821 ctaactttaa attgagtggt attttagagg atgattatac aggatatgta agtggtatag
    11881 taaacggtat tgtaggcaaa ggtgcatcag aaaatctatt acctaagaga tatattttat
    11941 cctctttgga ttttaaaata aaacagcaag agaagtttca agaaatagta aatcaattag
    12001 ctaaaaaaat aaatctttct cacaattcaa ttcaatataa ttggatttac ttaaatgctc
    12061 ttaaaataca gtttgaaaaa gatgaaaata gttctaatag tgatggtata tctatgatta
    12121 tattggtatc tttatttgtt gccttattgg ttttactggc ttctggactt gtaatctaca
    12181 atattttaaa aatctctgtt acaaagaaaa ttaaggagta tggatgttta agagcaatag
    12241 gagctgaacc aaaccagata tataagatag ttattttaca aatcttaatt ttatgtacta
    12301 ttgccatacc tattggagct gtaattggaa ttatatcttc taaaggcata actggaatgg
    12361 tcactaatat cttaaatcca gatatacttc tagcaaatga taataaagaa attactgagc
    12421 ttatacataa aaacacaaca gcatatatat tcccattagt attaagcact agtatatctt
    12481 tgattttttc acttatttca gcattaccat cagcaatata tgcttcacat gtctctccca
    12541 aaattgctat ggctggcagt actaccaaaa tcaaaagaaa aattaaacga gaaaaaacaa
    12601 taaaaaactt tgaaagacat ctagcctggc taaacttaaa aagaaataaa ggaagaacta
    12661 taataaccat actatcatta tttatgagta taacagtatt cgttgcactg agtgagttct
    12721 ctaatgtatt agatgtatct aggtcagtaa gtaatttaaa agaaggagat ttttccttaa
    12781 caaatgaaat atctggtttt gataagtcaa tactagataa aatagataaa atgaaaaacg
    12841 tcaatcgcac ttcctttata aagtactctg aatacaaaca gggcgaaata gatacagata
    12901 taaattttga aaatagtggt gagatgttaa aaatcattgg aattgatgag caaactttaa
    12961 aagacttaat gccttctatt acagattcta tactagaaga ctttaaaaat ggttctatct
    13021 gttttataaa aaatccgatt gctatttcta caccaggtgt aaaaactaga catacaaatt
    13081 taaaacctaa agataatatc acaattaaca aaaaacaact agatatatat agtacagtag
    13141 ataaaatgtt ctttttacaa ggtaatggct ggataaatgg tgttgatgtt attgtatatg
    13201 attctgttta taacaccttg acaaataaaa acaagttcaa ccagataaat atttatgcta
    13261 aagataaatc aaaattagaa caaataagat tgtctattga acagatttgt gaaaataatc
    13321 ctggctctca ttggatatca tatattgaat cagataaaca acttaaagag agttttaaac
    13381 aaatagaatt tctagcatgg gcagttatat tatttgtggg attgattggt actttaaaca
    13441 tcattaacac aactcataca aatataaata ctaggactaa tgagattgga gttaaaagag
    13501 ctattggtat gagtaatagt agcttatata agatgttttt atgggaaggt gtttattatg
    13561 gaatttttgc tactatattt ggttcaattg ctgggtatgt cagtgctatt attataaaca
    13621 tggcaactat agaaaagctt gattttacta atataccaat tacttcaatt ttacaagcta
    13681 ctattatttc tatacttgca tgtattatag ctactcttat tccgttaaga aaagttaaaa
    13741 agatgaatat aattgactgt atagatgtca atttataact attttacaga taataaataa
    13801 attaaattat caatgactgt ctctattttc ttttaaatct aactaataaa tctttttaac
    13861 tataatataa gctttaaaaa aggcctgtct caaaatagag ataagccttt tttcattgtc
    13921 gaaataatga aaatatattt aacttcacaa aaaaagagtg cctcacgaat taaaaatttc
    13981 gctttgagac actccccttt aatttaaaat atatagttaa atgctatgcc aaaatttcac
    14041 acatgctcca cctgattttg aattttctat tttaacagaa cctccaagct gttccactaa
    14101 ttgttttaca atgtaaagcc caagaccaga atgtcctcct ttagtctgcc tagcttcatc
    14161 tcctcgataa aacttatcaa gagccttttt taaatcttta gagctaaacc ctctaccaga
    14221 atcacaaatc tcataagaaa tacaattttt ttcatccttt acagtaatac taatattacc
    14281 acctgatgga gtgtattgca gactgttgga tatgatatta tcaaaaattc gtgtcaacct
    14341 atccacgtcg atttgaattg gggattgtat attcccctgc attttcaata taagttcaac
    14401 ttccttttga tgagcctgta attcatagtc ttgtaccttt tgcctcaaaa attcaggtaa
    14461 atttatagga acaagattta attgtatatt tgacttttct aagtcagacg tatattgcat
    14521 cttttggaca agagcagcac ttttttctgt attttctctt atcactgtaa gatacctatg
    14581 aagtttttca ttgtcatctg tattattacc aataagtgca tctgtatatc ccaaaataat
    14641 agaaagagga gattttaaat catgtgctag agcttccacc atttcaacac gttcctgctc
    14701 catcttccac tgtgcagata aagagccttt taattcgtct ttcatttcag aaaatgcact
    14761 acaaagttta ccgagttcat tatctgaata atagtcgatt tcaaaatcaa ggtccttttc
    14821 ttttatcttc ttggacgcat caatcaatag atgtaatggt tgattgatat tctttacaaa
    14881 gcgcttagaa agccatctag taaaacccac gatatataga aatggagaaa acagagccat
    14941 tataataact gcaaatacaa atctccctct aatatttgca aaggtgattt tcacttggta
    15001 gaatagaata acagctccct caatctttcc attatcccct ttgattggaa cagtatggat
    15061 ataaccacct ttacgaacag ttttattgat aaaattatta aataattctt cttttgtttt
    15121 aaatagtttt ttggggttag taccatataa aatattgcca ttattatcca caacttgata
    15181 tagcatatca tccccacgaa tcgttctttt taaaccttct tcattcgatt gtgataacaa
    15241 agttatgttt ttttcattga tgtatttttc aattctagga acttgtcgct cataatagtt
    15301 tggtggatag atatccttat ttaaggaatg aatatacaaa tagagagcaa atacataagt
    15361 aatcactgtg gcaactatac tggctattat aataaaaata aaagtatgtc taaattgggt
    15421 aataagggat tgatttttca tttaataacc tctctctctt tacattttat tccacttata
    15481 cccaataccc caaactgtgg aaatatattc tttttctggt gtcacagcag aaaacttagc
    15541 tcgtattttt tttactcgtt caacaacagt tgaggaatca ccttcagaat cacaccccca
    15601 tactttttca tagatttgtt ctcttgagaa aacttgtcct gcatggagtg ctagtaattc
    15661 aacaatatca tactctattt ttgttaaatc aatattctta ccatcaattt taattgcacg
    15721 ttccttcata tataagcata acttcccaaa atacaaagta gatctcttgt tctcttcatt
    15781 gatatactgt gaacgctttt ccctacgcag attagcttca atccttgcca taagttcacg
    15841 cagtccaaat ggctttgtta cataatcatc ccctccaaag gtcaaccctt tgattttgtc
    15901 ggtttctgat tgctttgcac ttaaaaatat aattgggcat aaaacatcat ctctaattgc
    15961 ctgacatacc tcaaatccat tcattttagg catcataata tccagtataa taaggtcagg
    16021 ctcctgtttt gataactcta tacctgcctg accatcataa gctatcaaca cttcatgtcc
    16081 ttttgccttc aattcatcct caagtagcat tactaggtcc atttcatcat caataatcaa
    16141 tattttactc aatataacac cacctttctc ttatgggaag gtcagtatta aaacaatatt
    16201 cgtctactaa taacttttcc ttccctccca cattttaaac caaataacgc ctcctatcaa
    16261 gaatataatc aaacctattg ctactactat aagctctata ctagctgttt gcatcacttt
    16321 agagtaaaat gcctcagttg aaatagttcc agcttcttta ataaaataaa ttcctggaag
    16381 catacctagt tttactggcc atgtccatgg aacaaatgcc catacttttt caccaacgct
    16441 agttaatcca agtattgctg ccatcaaaat tccaccgata ctaataccaa tagatgcacc
    16501 cataccccat gcaaaactca cccaaagatg aatagctaat agtggaagtg tcccaatcac
    16561 cacaagtcct gctgctgaca ggaataacca tattgttgct ccagatggca ctgcaatact
    16621 cattcctatg caaagtatca acgtagcaat aaatgtgcat atagttaggc aaaacagaag
    16681 aaaaagaaat tttcccagat ataatctaac acgagaaata cctacacata aaaaaccatt
    16741 aaaatttcca gcaagctctt cctcctgcac tataaatcct gctaaaatac ctactccaat
    16801 aggaatgatg aatacagtcc atactgtaaa aaatccttca aaagcaaatt cttgtgtact
    16861 tccagattta gttgtgagat aaaaaaccac acataatgaa aaaataatag gcataaaaag
    16921 agtaagccac tggacagctg tcctctttgc tcgaagccat tctgatgata atagctttat
    16981 catttgtcat ccctcctatt gaaccaagct gcagtaagtg ctgttaatac tataaacaca
    17041 accaaagaaa caacaatccc aataggaatc actgaagtat tcaaaagtgg gtctccagct
    17101 tctaatatag taccgttagg atgtatgttg atgattgggc ataccattct aactgcccaa
    17161 ctccaaggta ctgcaatcca aaatggtttt gtcgcagcaa ggacaccaaa tatcatacct
    17221 aaagctccaa ctcccatact taggaacata cctttccatg tagctagcca tagctgaagt
    17281 ggaagtatag caagagaaac aacccagcat acaatacttg cccctataat ctgtccaaaa
    17341 ggaactggac cagctttcaa tattaaacca gttataattg ttacgactat taaaactagc
    17401 gttgaaataa aactgtagac tgccatagct ataactttat taatccaaag tgtcatagga
    17461 gacacattgt gtgtacgtaa agcacgataa tttccagctt ttttttcctg gaaagctacc
    17521 aaagtagcaa acaatgcaaa tccaataggc agaaataaaa atgaccacca gttaaaaatt
    17581 aatgctaaaa gactttgcca cgcccaagaa gttgtttgag ataatggatt ttgcatgagt
    17641 gttgattgca ttataaatgc atatgctgca aaagacactg ggaaaaaaac aataagttta
    17701 cccataaatg ttcttttata ctttaaaagt tctgattgta aagcattcat ctgttttgtc
    17761 ctcctttaag aataacatct gtaaaaaatt cttctagatt ttcattaggg tcaggcattc
    17821 cttgaaataa tagtcgtcct ccatttataa ttcctatatt atctacaact tgagcaacct
    17881 ctgatagaat atggctagaa agaattacag ttataccttt ttttggaaaa gaagcaatca
    17941 attcacgcaa ttcttgaatg ccaaaggggt caagaccatt ggttggttca tctagtatta
    18001 acaactctgg gtcactcaaa agtgcaatag ctattcctaa cctttgtttc atacccatag
    18061 aaaattgtga agctctcttt ttacctgtat ttttcaaatt tactatttcc aacacttcat
    18121 aaattttatc tttaggtatt cccaatattt ttgtatgtac taacaaattt tcctctgctg
    18181 taaggtttcc atacaatgca ggggattcta ttaaagaacc tatttttgca agagattctc
    18241 gtttccaagg ctttctatca aaaataatac gaccatttgt tgggcgaaga agaccaacaa
    18301 gcattttaag tgttgtggac tttcctgctc catttggtcc taaaagtcca tatatactat
    18361 ttcgttcaat ttgtagagaa acattgttaa ctgccatttg ttctccatat ctttttgata
    18421 agttttttgt ttcaagaatt aaatctttca tattaatttc tcccttcttg taatacctta
    18481 aatctgttac taagagaata ctaacatgaa aaaataacaa ttctataaca cctactaatt
    18541 ttaataaaat ttaaaataaa aaatagagtt accaatttta ttttggcaac tctatttaag
    18601 tttatgtttt acagttatat tagatttaag cttagtttca ttatcacact aacttcaaat
    18661 ttactctata atccttaaat caaacactaa tttattaatc aaacactaat ctattaattt
    18721 atatttcttt agacatctaa tatagtttgc tactaaataa taattattta tatcatattt
    18781 atctaatcct ttaaaagaag ttatttcatc attaagctca tcactacctt ctacaaaaac
    18841 ataacctgtt tcaaattcca tacctacaat aatcttacag ccactataaa tttcctcttg
    18901 agtatcgtac aatttttttg catttccttc atttggaatt gtaaatacaa taggttttaa
    18961 ttctttatca ctggaaatct tttgtgaaaa aggcttgttt aacttaatat tattgataac
    19021 tacatgttta aattcctctg aagtttcttc tactattaca tattttcgct ttaaaaactc
    19081 tattatttct aaaacagact tagaatttac ttttaaaata cttttatatt tttcatataa
    19141 agatttccac tgttcaattt tttcctgtgg tacttcttgg atatgtgtac ttattttttc
    19201 ttgagatatt tttttcaatt aaactctcct ttcaatactt aaatatcctt ataaatctca
    19261 catgactaaa gttacaaggt tcctacttaa tagaattttg catacttaaa tatgtcttat
    19321 taattctcta caggatatct ccgtagttcc tacgattctt acataagtta cttattttaa
    19381 attgttatta gttagattat aaaaattatt tattttatca ctaatataat actcttaaaa
    19441 actttacaaa tcaatttaaa tttgctacct tttatttata acaacttata gtacatttct
    19501 cctatgcttt tcaatatatt acttttaaaa ggaggttttc attatgattt taaatagagc
    19561 tgagcttttc cgaggatatt ctttaaatag atttaacgag atatgcaata tattatcagt
    19621 aaataaaatt aaatataagt ataaagtgaa aaataatgct tactctaaaa aacctttttt
    19681 taatgaaata acacttggca atttaggcca aaaggaagat ttctcttatg agtacttaat
    19741 ttatgttcat aaagacgatt atgaacaggc agagtctcta ataaattcta agttgcgata
    19801 gattatctat aaaacatgac attctgttgt catgttttat atgttattat actttcaaat
    19861 atgctactat attttcaaaa ttgtgtgctt taaaactagc tttttttagt aatttaaagc
    19921 ttaaaactaa ggagactcgt tatatgaaaa taaatataaa atcaaagtta agtgaattta
    19981 ttaaacagaa caatcttttt gatgacagca gaataatatc ctatcttcct aatataacaa
    20041 tagaaacaga caaaataaaa actataatga ttaatgaggt tgtcccaact aacaccaatg
    20101 acgattttta tagtgtagat aaagatgctg attatttaaa aactactatt cctttatttg
    20161 acagtgcagg aataaaagta tctaacataa atgatatcct agatatgggt atctatataa
    20221 ctaatgcagt aaaacttcct aaatcagaat atacaataac tcgtgataca attaaattac
    20281 atatgcctat tttagaagaa gaaattaaat tatttaaaaa cctagaggta gtaatgttaa
    20341 tgggagatgt tgcaaaaaaa tcttttaata tgattactaa aaagcatata aaaaagaatg
    20401 tcatcccttc catttcaaca tataaacttc gtaataatga actttattat gataatttaa
    20461 gagtatttcc atcatatatt atgactggtg gaaacatact gattgaaaaa tcaaaatttg
    20521 aaatggcatc agaagatata aaaaaaatgt tcgagattat aaacggttga tattacaaaa
    20581 taataaaaac taatataaaa taaaaagtgc ctcaaaaact tctatttatg aggcactttt
    20641 attttatatt agtgtaacta tatactatta acataattta ttatttatat tgttcctttt
    20701 aatctctatt ccatttagtc taggtaacat tactctttac aagattactt tatatttctt
    20761 ttatatctct aacgttttta tttaataaaa caattattaa tacaagtcaa atatatctat
    20821 ttatctaaaa atatatcttt tacagtaata tctggatggt gatacttctt cctattcgtt
    20881 aaaaaagatt tttttacatt aatagcctct tttggacacc agtgaaaaca agctaggcat
    20941 ctttcacact cattacccca ctttggcttt ttatcaacta tacttatatt ctctacagga
    21001 caaacccttt tacatgtccc acatctatta catttatttt ctgcaaaaaa tttagtagtt
    21061 gcaatttgca tattcttacc tactaaacga agtacaacac tatctatatg tgactttaaa
    21121 ttgttttttc cttctatatt tccaatctcc aagttattga tacattttgc aatctcagct
    21181 accctattag tctgattttt caatctttct tcttcaacat ctggaggtgt tatcaaagca
    21241 tttccaggca tattgattaa aaaaccagca gataattttt tccccctttt tttaagtaac
    21301 ttatctatag taaataaact atgtccagct accccattac aagtggcaat ggcatatata
    21361 tgagtattaa tattaaaatt taatttctct acaaaagact ttactatatc aggaacatca
    21421 gcaaaataaa caggaaaaac aattaccaat atatcttcat ttatgtctat attattttct
    21481 tttctatgta tagctaaggg tataacttct ttacttccat ttaacgtttc ttttaaaata
    21541 tttgaaacta ctagcgaatt tcctgttcca gaaaaataat aaatcttact attcattctt
    21601 atccctcttt ctatatttct acatcatcaa tagttaaaaa gtctcttaaa ataggattta
    21661 tatttacttt ccaattctat ccaaaatatc agtaaacaaa ggcaattctt catcagagat
    21721 agatttaaat gtctctgttg catatatact tgcaatttca tttaatggtt cttctaattc
    21781 tctacctaaa tctgttagga atatttgaaa cttacgtcta tctttaacat ctactttacg
    21841 gacaattaat cccttatttt tcataacatc taagattctt gtcgtattag atttatcctt
    21901 acatgatttt tcacataaat ctatctgaga aattccatct tgctcccata gaaaccttaa
    21961 taacgcataa tggtcagttg ttatatcata tccattttgt ttaaacatct tttttaaatc
    22021 atcttttact tttaacgaag tacttactaa cttagttgta gcttcatata gtttctcaaa
    22081 atctttcatt ttacctccat ttaaataatc ccttgctcct cccatctatc aattattccc
    22141 ttatattgct caatatcttt aaaagccatt ggctttaaaa cagcatttat agcaataaaa
    22201 ttatagattt gagaaagcac aggtggattt ttcttttcct ctatgcaata aataaatttt
    22261 ttagatacct tttgtatctt tgattctact ttttcagtta taggattttg attaaatcca
    22321 gtttttatag ataaactacc acaaacataa cctcccgaat ctaagaccat ggattttata
    22381 aaagaaattg cttttgaacc acgtgcattt tcatatgtag taactgctat acatggctta
    22441 cgatacaata atctttcaag catcatatgt gctctatctg taaacacctt gaaaagtcca
    22501 gttacactac ttccataagt tgggctacca aatataacac catcactctt agtaattata
    22561 tcatgaatat actctacttt atcattttga ttgatacact tgcccatttt ataacaattt
    22621 aaacaaccaa tacaatatga tggattgacc tcacttaaat caaaataatt aatttttaca
    22681 tctggtatta atctttctat atctttatac aagtaagtca aaacttttga tgtagctcca
    22741 ttttttctag ggcttccatt tataactgta attatcattt ctatatctcc tttttagttg
    22801 ttatatcaac aataagtata tcaactatat ttttagctgt caatataaac catttattta
    22861 aagctatact tacacagctt aaataaaagt tttatttaac tacatgtgct tatttaatca
    22921 actataaatg aattattttt aataattgac aaactaaatt aatgataata tactttatgt
    22981 attacaaatg taagtagaag gaggtatagt atgaaaaagt taccacatat ttcagaagca
    23041 gaatatcaag ttatgaaaat tatttggaaa tatgctccta tcagcactac tgaagtaatt
    23101 gaaaagttgg tagaaacaag tacatggagt cctaaaacaa ttcaaacaat gttattgaga
    23161 ttagttaaaa aaggagcttt aacatatgaa aaaaatagca gagtattcgt ttatactcca
    23221 cttgttaaag aagaagaata cgtagctaca gaaagtagtt cttttttaaa tcgtttttat
    23281 aatggtactc ttaattctat ggtactaaac tttttagaaa atgataaact atctgaagat
    23341 gatattgagg aactgagaga aatcttaaat aaaaggacga ctaaggggga taaataaata
    23401 tgtatgcccc attctttata cgatttttac tcagtacatt aaccttatca atattaattg
    23461 ttgtaatttt acttgccaaa aaagtattta aaaaacatat ttctgcaaag taccaataca
    23521 atattggatt tatattgctt ataatgttaa taattccatt tgtccctctt aaatatatta
    23581 atcttggaaa tgtatttaac tatttatata cttttaatca acttggaagc agtactaata
    23641 ggacttctat gataaaaaat agttcaaatt ctgtaattaa taactcaaat gcattaaacg
    23701 atttttcagt atccctaaat caagttaatt ttgatagttt aaatatttta ttactaatat
    23761 catggataat tggaatttta atcatgatag ctattactat tcattgcaac attaaaataa
    23821 aaaatatgaa aaaatcaata caaattttaa aagatgagga gatagtattt atatttgaaa
    23881 agtgtaaaaa agatattggt ataaataagg attttatact atgcaaatca cctattataa
    23941 atacacctat tacatttgga tactttaaac cacacattat attaccagat aagtctatat
    24001 ctaaattatc tttaaaagat ataaaatata tcttacttca tgaattacaa cattttaaaa
    24061 ataaagatat actgataaat tatataatgt gctttcttca aatattatat tggtttaatc
    24121 ctcttgtatg gtatgcattt aaagaaatgc gtatagaccg tgaaattgca tgtgatattt
    24181 cagttttaaa aaagcttaat aaagatagtc atatagaata tggacaaact ctaataaact
    24241 ttgtggataa tatttcaaga ccatcaaatc ttacacttac atcagatatt ggtggttcaa
    24301 aaaaacaaat aaaaaagcga ctattgaaga taatggattt tcataatgaa tcaaatacgt
    24361 taaaattcaa aagcatttta atttttacat tgatagcttt aattgtattt ggaaatattc
    24421 ccaaactatc tattatggca gatatcaacg aaaaatatag acctacaaat gaacaaactg
    24481 tgtacgagga cttaagtcag tattttaaag gttttgatgg aagttttgtt atgtatgatt
    24541 taaaatccaa gcaatatcat atttacaata aagaaaaaag taaaacaaga atttctccaa
    24601 attctactta taagatttat agtgccttat tgggattgga aaatgggata ataacaagaa
    24661 ataattcaca tatcccttgg gatggaaagc atcattctaa tagttcttgg aatgaagacc
    24721 aagacttatt ttctgctatg gaaaactccg taaactggta ctttcagact ctagataaaa
    24781 aaacagggct aaaaaacata caaacttatc ttaggcaaat tggatatggc aattatgatg
    24841 tttcaggtgg tatctcaaac ttttggctag aatcttcatt aaaaatatca cctattgaac
    24901 aggtagaatt acttgaaagt ttttatacaa ataagtttaa atttgaagat aaaaatatag
    24961 aaacagtaaa agattcattg ttaatatcaa aaaaggatgg ggtatcactt tttggtaaaa
    25021 caggcactgc caatataaat ggaaaagatg taaatggttg gtttataggt tatgtggaaa
    25081 aaaatgaaaa tacttatttc tttgctacaa atattcaaag caaagattat tctaatggta
    25141 gttcagcatc taagataaca ttatccatat taaatgacaa aaaaatctat aatccttaat
    25201 atatttactg tacattctaa aaaattcaca taattttcat attaattatc aattaaattc
    25261 atatacaagg cttattatat aaacatagaa gatagtaaaa ctagcttaaa aacataatat
    25321 aataccctat acaaatagtg gcaactctcc ctcacatcct caattgttgc cactatttaa
    25381 ttttttgtat gaagttaaat atattttcat catttcaaca atttgggtgc aatacaatct
    25441 ctattttgaa acaacctctt taattgtttt agagtttatg aattatttct catactttaa
    25501 aaagattgaa ttactcttga taatcttctt ttgtagtcat tacatatcac ctactactca
    25561 acacatattc tttgacctat ttttacatcc ttgtttatat ccaaaatatt taccttctta
    25621 ccatctggaa acaataccat tgtcaaagta gactttccta attcatgtat tctctttaaa
    25681 tcaacattaa caagaacgtc tccctgttta accatatctc cttgtttaac agcaacatca
    25741 aagccatctc catttaatgc aactgtatca attccaacat gaattaatac ttctccatta
    25801 gttcctttaa tcccaaatgc atgtccactt gaaaccactg tttctaattt acctgaaata
    25861 ggagaaacaa tttttccatc tataatatca atagcaaaac catcacctaa cattttttta
    25921 gaaaatgttt catctggtac attttctaat gcaacaattt tccccttagc tggagacaca
    25981 aagttttcat tattttcatt aaacactaat tcttcgtctt catcttcatt tatagcttct
    26041 ttaggcactc caaataaaca tgttacaata aagcagaatg caaccacaaa tattgatact
    26101 aataagtatg tgattaaatt atatccatca tagatataca ttaaataaga aggtaaaact
    26161 gctaatccat atgaattaga ttgaatatgt aaaattgata atattgctgc tcctaaacct
    26221 gaagatgcac acataataat caaaggcttt aaattatatc gaagctgaat cccaaataaa
    26281 acaggctcac ttataccaaa aagttgagat agcattgctc caaccgcagt ttgtttaact
    26341 tgattatttt tagatttttt cataaatgct agacatgttc caatattcgc aaatccatac
    26401 attgcacaaa gagtaataag ggcattaaat cctgtatttg ctaatagtga tgtttcaatc
    26461 attacataag tatgatgtaa gccagtaata acagctaatg gatatgtaaa tccaataata
    26521 aatcctccaa ttcctaaagg caaatcaatc aataagctga tgatatcaac catttttaat
    26581 tctattgtat gcattatagg gcctacacct aacaaaataa ctaacattgt tattagcata
    26641 acaaaaaatg gtgtgaaaat aaggtctaat acattaggca tatgtttacg gaaccatttt
    26701 tcaagattag ctccaataaa tgctgtaaca atagctgtta aaacacttcc ttgacaacct
    26761 acaataggaa taaatccaaa tgccataatt gcttcaattt catttgatgg gtcagcaaca
    26821 gaatatgcat taggaagtat tggggaaact aacataagtc caataacaag tccaataaca
    26881 ggtgttcctc caaatacttt aaatgctgac catacaataa ttgctggtaa aaaagcaaat
    26941 gctgtttctg taagaaccga aacaagtgtc tgaatataca atggaatatt tgcagaagac
    27001 attccaaata atccaagtac attatcatta aacaaacaac cctttaatcc caagaataat
    27061 cctgttgctg caataactgg aataatagga acaaatatat ctgctagagt tctcataact
    27121 ttcttaaatc cagtttcatt atttttaact aattcatctt gttctttttt tgataaagtt
    27181 tttaatccca ttttttcaac ttctgcataa actttattaa ctattcctgt tcctaaaata
    27241 atttgatact gtccagaagt aaagaaaacc cctttaacct catcaacttt ttcaactttc
    27301 ttatcattaa taatttctct atctttaacc atcactctta atcttgtggc acaatgtgta
    27361 atagaaataa tattatcttc accaataatt ttaataagct catttgctat tttattatat
    27421 ttattcattt ttctacctca ctttcaataa tactgcatga aatggtttca aacgcactgt
    27481 tttatttaat agatttatat catctaaatt ttggaataca atatcatatt tttcttctac
    27541 tcttatttct acaggtttat cagaaaaatt ataataacaa tcaataacta ccaaatctaa
    27601 ttgccttcta tacgcaataa tatcatcact ttctatatca ataggttcta ttgaaccata
    27661 aatcaaacaa tcagaatact cactatcttg tctcaacttt atcatctttt tataaaattc
    27721 taaaatactc tctgaattgt taatctgact ctgtgcatta atatctttat aattttcaat
    27781 aacctttaac catggtgttg tatctgaaaa acctgcattt tctttatctg cccatggaaa
    27841 tggcgttctt gcattatctc ggcttcttaa attcacaaat tctaacgctt cttcttctga
    27901 gtaactttca tctattgaac gatagtattg gtcaatgcta gataaatcat taaaatcatt
    27961 tatggtatct cttttaaaat ttgtcattcc taattcctgt ccctgataaa taaatggggt
    28021 tcctcttaaa aagaaataca ttgctcccaa catttttact gcatcatcat tcctttcgta
    28081 ttgcaaaaga tactttgttg tagctcttgg ttggtcatga ttttcaataa aattagctgc
    28141 ccatccatgt tcctgaacat acatttgact atctaaaatg cattttctta aatctggaat
    28201 tgtccatgaa attcttttaa accactcact accagaagca acatctaagt cagcatgttt
    28261 aaagtcaaag accattgaaa agaaaccatc ttctccaata aaatcaccta gctggtcata
    28321 gctaatacct gctgcttcag caacagtcat acaatcatat tttttaaacg tattttcttt
    28381 taattcataa agcatttttt ctattccagg ctgatttcta actgtttttg tacatttaac
    28441 aagaccatca acaccatcac tttctaaact ttgaaaactt aaattctttt tgatgaatgt
    28501 aatagcatca actctaaatc ctgccactcc catttgagac caggtattaa tcatttggta
    28561 aagttcactt cttaatattg gattttccca attaaggtca ggttgttttt taccaaaaga
    28621 atgaaaataa tattcgtctc tattctctac cttttcccaa acacttccac caaaaacaga
    28681 cctccagtta tttggtaaat cgtttccttt tttaaaaata taataatcat gataaggact
    28741 ttctggattt tttaatgctt cttgaaacca aggatgttca tcacttgtat gattaagaac
    28801 taaatctaat ataattttga ttcctctatc tttactttct ttaattaact cttttaaatc
    28861 ttccatactt ccaaattcac ttgcaatatc caaataatca ctaatatcat acccattatc
    28921 gtccataggt gatttaaaaa ttggacataa ccacaatgat gtaataccta aattttttaa
    28981 ataatctaaa cgagaaataa ttccctgtaa atctccaatt ccatcattat tactatcttg
    29041 aaagcttctt ggataaattt gataaacgat ttctttttgc caccatttct tttccataaa
    29101 ttactccttt ttatatgata tttcttcttt ttaattcttt ataaattcca ttatcgaata
    29161 tgtcctcaca tatagatgtc gctatatctt taagttgttg atgactattt ttcattgcaa
    29221 ttgtaacgtc tgatgcttga aacatgacaa catcgttttg accatcacca aaacatatgg
    29281 tttctttttg agttactcct aatctttctt gtaatctctt aattgctttg cccttatgaa
    29341 aatctttttg aataatttca taatactgac tagaaatatc tctctgtgct aattccattt
    29401 tatcttgtag tatatttttc acttcgtcaa ataccttttc atttgaccat aaacaaattt
    29461 tatgtatatc ttgtgactta tactcttcaa tgttattttc atatgttatt ttttcttgga
    29521 tatgttgttt atttatacaa gaattagttc ctttcaactg attcattgtt tcaaatattt
    29581 ctttggcttt ttgattcatg aaaacttttt cctgactctc aatcgaaaaa gcaacttctc
    29641 tcttttttaa taaacaaaca acttccttta tcaatctttg attaaaagat tgattataaa
    29701 gtaattcacc atgatattga atgtaattac ctcctcctgc aatatatcca tcaactccta
    29761 atgataaaac atcatcttgt attgtaccca tacttcttcc agtacaaata acaacactgc
    29821 aatgattctt ttgacataaa cgtatagcat gctttgcaga ttctgggatt ccatatacct
    29881 catctctaag cgtaccatct atatcaagta ttaataattt gtacaatttc atcttccttt
    29941 cttactatca aaatcataat agcattcaaa aaaaaagata tcaatatttt gatatctttt
    30001 aaaaaatatg ttcattttta gcacaaattt tcattttcgg ggaatatgtt cactttctaa
    30061 atacatcttg tatttaatat aaagcagttc aattaaaata aaataaggtg ttgttacatc
    30121 gtagtccagt tgtttatcta cagaaataga tatagattga atatacaggt tttcatcaca
    30181 taatcttgct aaaggattac ttatcatttt tgtaatagaa accatataaa ttcctttcat
    30241 tctcatttct ttagcaaaat caataattgt agatgcatct ccattcaatg aaataaagaa
    30301 aatcatatca tctgttttta taaaatgatt aagtgcctga atcatatcat aaccataaac
    30361 atcatatata attttccctg ttggtaagaa aatccttttc atctctttag caactctttc
    30421 ctgagaataa ccttctccaa agacgattat acgatttgcc tttttcattc tttcaaacat
    30481 aatcgaacaa tccttcttct ctatatcatc tatcacctta ttataacaat ccattaattg
    30541 gtgtttactt tgatttttat attctacttc tgtttcattt aagcgtataa taactcttaa
    30601 ttcactatat ccaggtaatt gtagtttttg agcaaaacga gaaagtgcac ttgtagatat
    30661 atggtatttg tctgcaaatt catctataga aagtttaata caatcttctt tatgattaag
    30721 aatacactca cagatatact tatcatttgc tgtaaatgaa ttataatatt tattgaaaag
    30781 tccttcaatt ttcattcttt tctccttcta tactctatgt aattcatatg aagcaaatct
    30841 aatagagcat aaaatgctcc tacgacttca taagatatag cttgtaatgt atcaagtttt
    30901 tgcgtttcaa catacagatt atactcacaa agtgttgcaa ttgtattatt atcaagccta
    30961 gttaaagaaa tcgtatgtat atgattgttg ataaattttg caatttcaat tcctgctttt
    31021 gtttctccag acaaagaaat gataataaat aaatcatttt tttgaaatga ttctctcata
    31081 aattcaattt cacctatatc aaataagtca ataacacatt tacctactga aagaaatatt
    31141 ctctttattt cttgagctaa acttttctgt tcattacctg tcccataaat ataaattgtt
    31201 tctgcatcat atattatttt acaaatatct tgaaatgata ttttttgtaa ttcattcatt
    31261 aatagtcgat aattctcgca aacatcatga aaattattat cattattaac aaattctagt
    31321 tgattatttt taagtaaata ctttaaatca gagaatgaat ctaatccaat ttttctacaa
    31381 agccttaata aagtagctct agaaacatta cattcatttg caattttttc acacgaaaaa
    31441 ttacggtatt ctctttgaca aatcaatatt tgtttaataa taattttatc attttcattt
    31501 aaattatcat aattttggtt aactaacgat tctaatctca ttttttccac tccctaaata
    31561 ttattttaat atacattagt tgctttttct agggaagagt tttaaataat aaggataaaa
    31621 taatcatttg attttatttt tattaaaata aaaataacct gctaaaagca ggcaccaaaa
    31681 agtacttatc ctttcgaaca tgtactttag atattgcttt cttcggaagc ttcatctctt
    31741 catactctaa aatatagttt tttctaactc aaaagtattt tccatggtag aaattacttt
    31801 aattcatctg ccatttactt tttatcttat ttaataatta ctattacttg aatatttact
    31861 tctttaagta aatttcatag ttaacaaagc taaaactatt attatagatg ttaaaataca
    31921 aaattgtaag tattgttata aatatgctta cagctacaaa tatacatgat atattaaaaa
    31981 gaagctgtaa attattatca tacatacaag caactatgcc tctattaatc catgttaatt
    32041 tttattattt aatacaagga gttccatgag acatacatat ccattcatat tttaaattat
    32101 ccaattctct tatagatttc accatctttt tataatccca attccatgga ttaggataag
    32161 gaactatatt tccattctta tttttgacta aatcacctgc aaataataca gcttcaaaaa
    32221 tcatgcagac atgccctgga gtatgaccag gagtatggat aatttttata ttcccaatct
    32281 gcatattctc tccataaggt tcaacatcct taatgagcct tctggaaatt gcctttccaa
    32341 taaacttctt aaacccaggt ctatccttct ctcctataat aaaaggtata tcctctacat
    32401 gagcccatac ttttgctcct gttttttctt tcaataattt aatattagat atatggtcaa
    32461 catcatgatg agttaataaa atatgcttaa tatctgtaag tttaatgcca agtgttttta
    32521 attctttaat tatatttttc cccataaaag gaagacctgt gtctataaga ataatttctt
    32581 tatcaaacac aataaaacaa tttgagccac gagtactatc taacattaat acattttctt
    32641 ttatcttcat aaataaattc cccttatttg gtattttacc tatataatta attaataaag
    32701 ttataaatag ttataatact tgatattaat tttatttttt attaaagtat actataggta
    32761 tacaagtatt atatttacat aagtatacca tcagtatact tttttatcaa tagaaaggaa
    32821 taatttatat gtcagaatta tcaaaaagag ataaagaaaa aatacaaaga gaaaatgaga
    32881 ttattgataa agcagaaaaa ttattttgtc ttaatggatt tgataataca actatgaatg
    32941 aattagcaaa agaagttgaa tatactaaac gcaccatata caagtacttt tcatgtaaag
    33001 aagatttatt ctttgctgtt gtcttaagag gatataaaag actttgggat aatgttaaaa
    33061 tagaaagtgc aaaaggcaaa acagggtttg aaaaaataaa actttcatac tttgcttttc
    33121 ataaatttta ctctgtagaa ccttctctat tatgccttat gggaatgatt ggtattgtaa
    33181 actctgaaaa atcggatact gatatgctgt ttaaagaaaa gtttttttct tttaataaat
    33241 ttatgtttga tgaaatacaa ggaatgtttg aaattggaaa aaatgataga agtattaggc
    33301 atgatattga aatacctact cttatgtatt catcaatatt tacacttaca ggatttttta
    33361 atttactatc tgtaacagga aaatcatacc tgaacaactt taatatagat gaggaaaaat
    33421 ttattgaaac aactcttgct cttttaatag attcaattaa agcataaacc taagtttata
    33481 aattaaagtt tatatactta aatgataatt ttttctatct ctaatataaa aaatattaaa
    33541 cataaaacta ataacttagt taatggaata actaaattac tgaaaggatt aaaagtaaat
    33601 ggctaaaata cttcttttag aagatgatga tacaattaca tttggaataa aaacttccct
    33661 tgaaaagaaa aatcacactg tatgttgtta taatacgatt gctgaagcta aaaaaaattt
    33721 tgataaaact attgatttaa ttctgcttga tttaaatcta cctgatggta ttggatacga
    33781 gttttgccaa tatgttaaaa gtatagaaga tactccagtg atatttttga cagtccgtga
    33841 tgatgaaaaa gacattatac gtggattaga tatgggtgca gatgactatg tggttaaacc
    33901 gtttttgctc tcagtacttc agtccagaat taatgcagtt cttagaagaa ctcattcaaa
    33961 tactaacaat actattacat gtgaaaatat aagcttgaat aaggttgaag tcaaagcata
    34021 tttagataat gttgaagtac ctttgacagc aggagaatat aaacttcttc taagtcttat
    34081 ggaaaataaa aatagagcta tgactcgtac aaagttacta gaaatgctct gggatgtaga
    34141 tggtaatttc gtaaatgata acactcttac tgttacaata aaacgtctta gagaaaaatt
    34201 aaaaaatcca ccttgtataa aaacgttaag aggcatagga tatagaatgg aggacagcta
    34261 gtgaaaactc caagaaatat caacagtaca gttgttttta taatattctg cttaattgta
    34321 acttttttat tgagtgtaat tctaacaact ataacttctt ttaatgaata caatgtactg
    34381 tctaaggctc ttggtgcatc atatgagtac aatcctaagt ctacagaaag tatactaaaa
    34441 tcactgaaaa attctagtga taaggatttt aaaacaggaa atgaaatttt atcaaaacat
    34501 ggatattcta aaagtacatt ttggagtaaa aacttttttt attttctagt gatatcgttt
    34561 ggtataattt caacaatggc tacagttata tatataatca aacatagaac aaataagcaa
    34621 aaactgagta gaataaacaa tcttactcaa tacttagaag aagtgaattt aggaaaagag
    34681 tctgtacttt tacgatgtga agatgaattt tctcaccttg aagatgagat atataaaaca
    34741 gttggggaac ttcgttgttc aaaagaattt gctttaaaag aaagacaaac tctttcagat
    34801 aatcttgcag atattgctca tcaacttaag actccaatta cttctatgtc acttatggca
    34861 caattacttt cagaaaattg tccagatgaa gaaatagatt atattaacag acttacaaat
    34921 caaatctcaa gacttgagag actagtttca tctttactta cattatcaaa attggatgca
    34981 agtactttaa tatttgaaag caaacttata gatgtacatt ctcttcttac ttatgcaatt
    35041 gagcctatag aaggttcttt aagagaaaaa catcagacat ttactatcga ggcttctcct
    35101 tcggtagaat ttgaaatcga tattaattgg actttagaag ctcttttaaa tattcttaaa
    35161 aattgtagtg agcatataga agatggtgga tatatagttg cttattatag tcaaaatcct
    35221 ctatatgttg agattatcat agaagataat ggtaaggggt ttgctcagga agaacttcca
    35281 tatattttta atagatttta tcgtggtaaa aatgctagta aggacagtat tggtataggg
    35341 cttgctctat caaagtctat tatagaacgt caaaatggta ctctacatgc agaaaattgc
    35401 cataatggtg gtgcaagatt cataattaaa ttttacacat aaaatgctgg attataggta
    35461 aaatacctat aatccagcta tatctatatt ctatgttatc tattgtttta gtaatatact
    35521 tctatttaca tttaaggttt tattaaacaa acaacttaac tatccctata cttgtaagta
    35581 gtcttaaatc gaaaccttta aataagttca aatagatttt gtttatattg tttcattttt
    35641 tatagattct actatatttt cattcttcaa ctgcttgtat cctgtcatat atgatgctat
    35701 tacaataaaa agtatcaata tagtaaaacc tattattgta gatataggtg caaatggtaa
    35761 atactctata aaatatattt catttatacg tagaaaagca tacactattc ctatttgcac
    35821 aggaatacta agtagtaatg gtgtaattcc taagaataaa ccttccaaaa taagcatctt
    35881 ttttatgcct tctggagata atccaacaga acgcaacata gcaaactctt gtcgtctact
    35941 tctaatattt cctgacactg tagcaagtac atttgataat ccaatcatag ccaataaacc
    36001 tgtaataaag cctactatta aattcatggt ctttattcca ctagcctttt gtttttcact
    36061 ttctaaaaca tcctcaatac tataatctcc tgaaccatag tctttattat aaatggactc
    36121 taatttttct cttactctag gaatgtcctc acgattattt actttaaata ctcctatcag
    36181 cctatttgaa cgtaacctac ttacttcatc ataattttta gatatttcct gtaccataga
    36241 cattggaact atttgcatta atgtatactt tgaactagta tctactattt taggaagtgt
    36301 gcttgtaata gctcccactt tcatgttgta agtataatcc cctttatctt cgtcatatac
    36361 tttttcattt aatttaatgt tatctcctat tgaaagattt aaataatcta tatatacttt
    36421 atttctacgt gtactacgat taatatcttc ctccttatta tatacaattg aggttggatt
    36481 ttttgtatta taaaataact ttgggtctac agaaatttgc ctacaatatt ctgtaaaact
    36541 cttatcatca agcccaatta tatttgaaat tatacgaaac ttgccatcac gttctatagg
    36601 agagtatttt ttagatgaaa ctatactttt aaatcctcca tttttcgcaa gttcttttga
    36661 tgcatctttt tcagtcagcc aagtggaagc agacattttt tgataatata gtgaactttt
    36721 tacaccttct gtattatcta atttttcaat gaaagcagac tctataggtt cactattttc
    36781 caaataaact gctatatctc tttggtcctt ataattatca cttccataaa cagcttttgc
    36841 tccttcttga tttgcaatta tatgcaaaaa acatgtaagt aataaaaaag ataatgttaa
    36901 agatattgtt gcagtacgat aagatttttt acgagcacgt agtgcgtttg atgcaagttc
    36961 tccttctatt ccaaatatct ttcctaatga atatttatgc gactttttga ttttaacact
    37021 atctccttgt cgtattgctt ctataggaga tatctttgat acttttcgtg ctggtataag
    37081 tgcagaaatc cagactgtta ctattgtaag taaaactgct ggcagaaaag caggaatacc
    37141 ataagtaaat accacttctg gaacatcagt atgataatta actgaattaa cataaactat
    37201 aagcctatta cacaataacc atcctaaaaa taaacctatt ggtaatggta taattgtcag
    37261 taaaaagcct tcaaacacta cagacctttt aatttgtttt ggtgatgcac caacactaga
    37321 taatatccct aactgagtaa gtctagcatt tgcagacagt gaaaacgcgt tgtaaatcac
    37381 cattacaaac acggctactg taaaaattgc tattgtaaga tacataatag gagttgaaaa
    37441 ttttgatata ctactcatag atgctttctg ttctggtgaa aagactaaca tctttaaaag
    37501 ataattacta ttgtatttaa gattgtattt tccatattca ttagtcttcc atcccaatga
    37561 tttagcaagt tttggaagtt ccttatacgt gtctcttata tttttaaatc gcaagtacac
    37621 agttatacta tcattaggtt ttatacttgt tttatcaaga tatccaagag ctgtatatgc
    37681 aggtattact gatgaagtag aaacatctac ctttcctact attgtcaatg tagcctctga
    37741 aattttttta aaactttccc ctttcgattt tggggctatg ggttcaagag gctttccatt
    37801 taagattcta tatcctattg ggagagtaat tttatcacca atttttacac ttggattatt
    37861 ctcaaaatat tgttttgata atgcaatttc attagcatta tttggtcgac gaccctctat
    37921 tatagtatcc ttttctggca tagaattcca atactctgat gtagcatttc tataaattat
    37981 ataatctctt ttctcatcat taattttgcc tacataccat tgtcctttta ccattacatc
    38041 atcaactgaa gaaaaatttt caattaatgg taagtcactt ccataagtat agtcaaacaa
    38101 ttcaccatgc cagttacctt ctttctcaat tgaaagtctt ataaaatctg tccacatggt
    38161 atacaacagt ccacacaaag aagacatcat ggttgtagta agtaatatag ctaacattat
    38221 agctatacta ctacgtttat tgcgtcgtac aaagtctaag gtgtattctt gaagaatatt
    38281 catttcttca ccaccttttc agagacaatc actccatctt ccatagttac aatacgattt
    38341 gcctctagtg ctattttctc atcatgagta ataagaagta ttgtctgatt aaatcgttta
    38401 tttgataagt ttaacaagtc tacaatttct tctgaatttt ttctatcaag attaccagtt
    38461 ggctcatctg ctaataaaat agctggtcta tagattaaac ttctagctat agataccctt
    38521 tgttgttgtc cacctgaaag ttgacttgga agatggttta atctatcaga taatcccaat
    38581 atagatacaa tctcagagaa tctatcctca tccacctttc ttttatcaag taacatgggt
    38641 aataatatat tttttctaac atcaagggta ggtataagat tataaaattg ataaataaga
    38701 cctacttttc tacgtctaaa aactgcaaga gcttcttcct ttaaacttga tatttctgta
    38761 tcttcaacat aaatctttcc agatgtaggt ctatctactc ccccaagcag atgtaacaat
    38821 gtagatttgc cagaaccaga tgctcctaca atggatacaa aatcaccttt ttgaactgat
    38881 aaatttacat tattaagggc tgtcactctg gtttgatttg aaccatatat ttttgtgaga
    38941 ttttcacatt ttaatatttc catatacaat catctccttt atggttaaat tttagcaacc
    39001 taaaatgaca ttatagtgac atgaatacaa atataaatta ctattaaaaa tattgtttag
    39061 tttttgcaca ttatttaaaa ttataatata aaacaaaaac tatgcaatat attttattta
    39121 tacttttaat atattacata gtctttaaaa ggtattaact ttaaatctat aggtattcaa
    39181 tttaataatc aatagcaagt attttatgta ctaaaggagt tttgctctat atagactcaa
    39241 tttagtaaaa ttatttaata aatattacag actataggta aataatattt acaaataaaa
    39301 ttaagtttat tcccttacac tataatattt cttaattata ttaattgcaa tttcctttac
    39361 ctttggccct gtaatttctt tattggaatc atctgattta atagcaaaat aataggtgtc
    39421 accttcacgc tctagcatac caacaaacca tgcatccaca cgtttatttt tttcatcaaa
    39481 tcctgttcca gtttttccat atacatttat gtttttatca tttatatcta ttttcataat
    39541 atctcttaaa atattaatat gctctttttt aaagtttgta tctccctcaa atatttttgc
    39601 cattgtttgc acttgttctt ttggagatat ttgtaatgaa gattctaacc aaaatccatt
    39661 taaatgtccc tttccatttt ttaaatcgcc ttcccattcg ctaatatcgc aattcccata
    39721 ctttaaatca tctaaaatgt tttggacaga tttagcatca actttatcta tcaatttttt
    39781 gtaataccaa acacaagact ccttaaatgc ctcttctaaa ctaagatttt tattccaatt
    39841 tttatttgga tactctgtac catcatatcc cataactgat tcttttgagt ttattacccc
    39901 tttttctaaa ccaattaaag ttgaaactat tttaaaagta gaacatggtg accttcttgt
    39961 ttcaattaat tctttgttat atatattata ttctttattt ttagtattat aaaaaatagc
    40021 tcctccacta ataccttcaa aacaatcact atagtcaacc atattaattt tttctttttt
    40081 gtttttatca ttgttttcaa ttttggattt atttaattca gacttattta attcagattt
    40141 tatataattc ttatcagttt tttgatttat atcgttatgt tttttcccta cataatacat
    40201 taccataact acaccaacca ataagatagc tatccaaata aaattctttt ttcttttcat
    40261 aatttatatc atctcccata tttaaattta taacctacta ttaaaatagt agacattatt
    40321 tgtaatatac tccaatctag gttctactta taagaaacaa gactaaatga atagctgtat
    40381 ctcttatatt ttcttcacct agtacaatta tgttgattaa acctattgcg aagataatta
    40441 ggtaactatt aataacatcc tgtcctcctt ttaatttgtg atataataat tgattccaca
    40501 tttaaaactt actattgtaa tatttaaata ttacaatagt aagttttaaa tgtcaagtta
    40561 gtttaggaaa gttattttaa ttgtataatt gttattacat ttataaaata tggcatgttt
    40621 aaaattattt tgctattggg aggattaaga taagcagtat tataaaagct ataaattata
    40681 aaatttaata tataatttat agcttttact tttacaaata ttgtttttat tgatttatta
    40741 atg
//
LOCUS       DAEPHU010000032        40584 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 01A10CD0081
            SAMN05941466-rid12468953.denovo.032, whole genome shotgun sequence.
ACCESSION   DAEPHU010000032 DAEPHU010000000
VERSION     DAEPHU010000032.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941466
            Sequence Read Archive: SRR6291087
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 40584)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 40584)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068158.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 22:43:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,892
            CDSs (total)                      :: 3,805
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 87
            rRNAs                             :: 8, 1, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 55
            CDSs (without protein)            :: 55
            Pseudo Genes (ambiguous residues) :: 0 of 55
            Pseudo Genes (frameshifted)       :: 21 of 55
            Pseudo Genes (incomplete)         :: 28 of 55
            Pseudo Genes (internal stop)      :: 16 of 55
            Pseudo Genes (multiple problems)  :: 8 of 55
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..40584
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941466-rid12468953.denovo.032"
                     /strain="01A10CD0081"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            9..695
                     /locus_tag="KR231_001794"
     CDS             9..695
                     /locus_tag="KR231_001794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007285877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YwmB family TATA-box binding protein"
                     /protein_id="HBH0004173.1"
                     /translation="MTISYADTSINTKYNRLSKALEISEANFKFYNVKINSVINHNLS
                     NKEFHNIFIEIINNLKLDKKGINWNQKGSGDKIQLCATIKGSDKEISIKGINKNNKES
                     YIVVDILDNKVYKHKEVIYSNVENVLNKYSSQVDVSACIVGEYTKRLQNNKYDDILQK
                     ILYNMSAKQIDEVKDVNFLSITAYSKVLNDYELEYLGEKINLNIGIKYNEDDGRTLIY
                     IATPIIKLDY"
     gene            716..1969
                     /gene="murA"
                     /locus_tag="KR231_001795"
     CDS             716..1969
                     /gene="murA"
                     /locus_tag="KR231_001795"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HBH0004174.1"
                     /translation="MAKIIVKKSNPLKGSVKIDGAKNAVLPIIAATLLANGKSTLNGV
                     PNLRDVHVISDLLRHVGAEVEYKENTLTVDASNIKTCEAPYELVRKMRASFLVMGPLL
                     ARFNSTKISMPGGCAIGTRPIDLHLKGFKALGAKIEMDHGFVEAATEKLVGNKLYLDF
                     PSVGATENIMMAASLAEGTTIIENAAEEPEIVDLANFLNEMGADVKGAGTNTIKIKGV
                     KELKGAEHNVIPDRIEAATYMVAAAMTKGDITVENVLMEHLKPVVAKLREAGCEITEM
                     DNSVRVVGPKVLKPIDIKTLPHPGFPTDVQAQFMAMLTVANGTGVVIETVFENRFMHV
                     AEFNRMGANIKIDGRSAVVNGVDELHGAAVNATDLRAGAALILCGLIAEGETQIGEIY
                     HIQRGYVDIDKKITALGGQIEIVED"
     gene            2056..3120
                     /gene="spoIID"
                     /locus_tag="KR231_001796"
     CDS             2056..3120
                     /gene="spoIID"
                     /locus_tag="KR231_001796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009887965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage II sporulation protein D"
                     /protein_id="HBH0004175.1"
                     /translation="MKNPLVVLLGFVTCSVLVPSLITLVSYKNVELTEKAESPVSINK
                     TIKKSDIEDKGNKEEKNTVNYETVNKKAPIINVYNHITGKTEKMDMENYLCGVLAGEM
                     SSEFDIEALKAQSVAARTYVVYKQEHGKSSKHKNAVVCTDYKHCQEYKSYDTLKKLNG
                     EEWIKNKYSKIQEAVRGTKGQIITYNDKAILPLYFSTSSGKTENSEEVFSAKYPYLKS
                     VESPYDKYSPKFASTLKISNTDFVKSLRRAYSTIVIDVNNLSKQVSITKRSDAGTVEK
                     IKLGNKELTGKDIRTVFKLNSANFDIKFGEGYIDFVVKGYGHGVGMSQWGAEGMAEEG
                     YKYYDILSHYYTDTKIKDIY"
     gene            3186..3854
                     /locus_tag="KR231_001797"
     CDS             3186..3854
                     /locus_tag="KR231_001797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M23 family metallopeptidase"
                     /protein_id="HBH0004176.1"
                     /translation="MKKKLLEKDGFYLSLFVCVCLLAVGGVWFTNNNVDKLASNKGIM
                     ENANKDSEEEIHLIEKDKKDAIPTATDSKQNLEKAKSKEENKSSTTKLNYIGDKVIRG
                     YSEKEPSYSKTLDVWETHKGVDISCTKGKEVKSLLNGIVVDVFNDEEYGQSVKIKSDN
                     NIVVVYSNLDKNVSVKKEQKVTEGQSLGTVGSTSQIESEEGIHVHLEAYSGEKSIDPM
                     SLIK"
     gene            3952..4212
                     /gene="spoIIID"
                     /locus_tag="KR231_001798"
     CDS             3952..4212
                     /gene="spoIIID"
                     /locus_tag="KR231_001798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sporulation transcriptional regulator SpoIIID"
                     /protein_id="HBH0004177.1"
                     /translation="MRSHIEERAIVVAKYILEKNTTVRQTAKTFGVSKSTIHKDVTER
                     LKEINPSLAKEVKNVLDKNKSERHIRGGLATKLKYEKEHKKM"
     gene            4409..5428
                     /locus_tag="KR231_001799"
     CDS             4409..5428
                     /locus_tag="KR231_001799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein"
                     /protein_id="HBH0004178.1"
                     /translation="MAGADIGIDLGTANVLVYVSGKGIVLEEPSVVAIDNRTDSVLAV
                     GEEAKKMIGRTPGNIVAIRPLRDGVISDYDVTEKMLKSFIDKIVDKKGFGRFFMPRIM
                     VCVPTGVTEVEKRAVEDATRQAGAREVYIIEEPIAAAIGAGVDISQPNGNMIIDIGGG
                     TVDIAVISLGGAVVSESIKVGGDRFDDAIVKYMKKQHNLLIGERTAEKIKFEIGSAFK
                     REEEKYMKITGRNLITGLPSSITINSTEMLEALRECVEQIVVATHAVLEKTPPELAAD
                     IGDVGIIMTGGGSLLYGLDKIIEQRTGITVTIADEPLSCVAKGTGIALGSIDLLETGG
                     SFKRK"
     gene            5444..5872
                     /gene="fabZ"
                     /locus_tag="KR231_001800"
     CDS             5444..5872
                     /gene="fabZ"
                     /locus_tag="KR231_001800"
                     /EC_number="4.2.1.59"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxyacyl-ACP dehydratase FabZ"
                     /protein_id="HBH0004179.1"
                     /translation="MLNIDEIKKLIPHRYPFLLVDKITELEVGKRAVGIKNVTVNEPF
                     FQGHFPEYPLMPGVLIVEALAQVCGVAMMSVEENKGKLGVFAGIDKVRIKREVRPGDT
                     LTMEVEMTTLRRNIAKADAKAYVGEELVCKGELMFALVEK"
     gene            complement(5983..6492)
                     /gene="yyaC"
                     /locus_tag="KR231_001801"
     CDS             complement(5983..6492)
                     /gene="yyaC"
                     /locus_tag="KR231_001801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009887970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="spore protease YyaC"
                     /protein_id="HBH0004180.1"
                     /translation="MYLAKVNYSDDDVIQMLSSVLKTIINENTIVVCIGTDRAIGDTL
                     GPLVGTILKNSNFKYPVYGTLDNPIHALNIYESLDTIKNTHIQGNFLAIDACLGSQSN
                     IGNIQIREGPILPGKGVGKKLPQIGNYSIVGIVDKIDENNKLSFNNIRLSFILDLAET
                     IALALLVST"
     regulatory      6681..6784
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00162"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="SAM riboswitch class I; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="S-adenosylmethionine"
                     /db_xref="RFAM:RF00162"
     gene            6920..8113
                     /locus_tag="KR231_001802"
     CDS             6920..8113
                     /locus_tag="KR231_001802"
                     /EC_number="2.5.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine adenosyltransferase"
                     /protein_id="HBH0004181.1"
                     /translation="MARHLFTSESVTEGHPDKICDQISDSILDALLEKDPQSRVACET
                     TVTTGLVLVAGEISTSAYVDIPKLVRETVREIGYTRAKYGFDCDTCAVITSIDEQSGD
                     IAMGVDEGLESKTGEEIEEEIEKVGAGDQGIMFGFACNETPELMPLPISLAHKLSRRL
                     TEVRKTGLVDYLRPDGKTQVTVEYEGSKAVRVHTVLISAQHCETVSNDKIREDLINHV
                     IKEVIPAELLDEDTKIYINPTGRFVIGGPQGDTGLTGRKIIIDTYGGYSRHGGGAFSG
                     KDPTKVDRSAAYAARYVAKNIVAAGLADKCEIELAYAIGIARPLSIFIDTFGTGKVSE
                     EKLVELVNKHFDLRPGAIIRDLDLRKPLYKKVAAYGHFGRTDIDLPWERTDKVEQLRK
                     DALGE"
     gene            8428..9525
                     /locus_tag="KR231_001803"
     CDS             8428..9525
                     /locus_tag="KR231_001803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0004182.1"
                     /translation="MSGKVNIKTVISFAGAYVATVIGSGFATGQEILQFFTFYGYAGI
                     IGGIISMVLFSWFGAEVIDKGRELKLKEPIKIYQVYCGKYLGTFFEWFGPLFLFGTLV
                     IMIAGAGATLSEYYGLNPYVGRIGMTIVSLITVSLGLTRLSKILGNIGPIIIIFTLLV
                     GAISLFSNIDALSNAGNMVDSLNIKTATSNGYFSGVLYTCYNVIIVITFLTGMGASAV
                     NKKDAVWGGIVGGVALMAAAIMMNLALLSDIGNIYTKEIPALYLADKISPIIGILFSV
                     VLLLGIYTTAVPLLWSVTNRFVEDDHPKFKIITIVVSILACIGGLLPFDKLVGTLYPY
                     TGYMGILILLCMLYRRITKTEGYKENKSEIS"
     gene            9789..12008
                     /locus_tag="KR231_001804"
     CDS             9789..12008
                     /locus_tag="KR231_001804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent RecD-like DNA helicase"
                     /protein_id="HBH0004183.1"
                     /translation="MEKLEGMISEIVFKNEDNGYTIAHLVNENDEIVVVGCMPTLAIG
                     ESIEVEGKWVNHKIYGTQFEVNSFMPVTPSSLEGIYVYLSSGMIHGIGEKMAKRIIDK
                     FGVDTLEVIQNSPEKLQEVEGIGSKKVKQIVKSYEEDRELRNIIIQLSPFGITPNYCL
                     KIYKKYKSSAIEVINKNPYQLAEDIRGIGFKVADSIANKIGIDKNSKDRICQGILYTL
                     NKSLSNGHTYLPEHVLIQDSEKLLELNGEIIKECVMMLVYNQKIHVEKVNNENLIYLM
                     PYYLAENGVCSQIVKLSQYEFEDLKIDIDNEINVLEEDKKIKLAEKQILAVKESVNSG
                     VLIITGGPGTGKTTTINAIIDIFENNGKSVTLAAPTGRAAKRMSETSNKEAKTIHRLL
                     EMGFSTDDDLTFFKDEEDPINSDVIIVDEVSMVDIILMYNLLRAIKLGTRVILVGDSD
                     QLPSVGAGNVLKDMINSNIINVVKLNEIFRQAQESMIIVNAHKINNGEPLYLNTKGKD
                     FFFIRKSTNEEILNEIIGLVNERLPKFYKVDKLKDIQVLSSMRKGELGVTNLNIELQK
                     YLNKKEKFKVEESFSKRLFRVGDKVMQVKNNYTKKWETEDQKESGEGIYNGDIGYVYH
                     IDKDKKTIYILFDQTKIVSYLYDELDEIDHSFCTTIHKSQGSEFPVVVLPIAWAPPML
                     LSRNLLYTAVTRAKKLVVLVGDVKYLEYMIKNNRVNQRYSNLGYKLNKFKQEGLLIE"
     gene            12011..12793
                     /locus_tag="KR231_001805"
     CDS             12011..12793
                     /locus_tag="KR231_001805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComF family protein"
                     /protein_id="HBH0004184.1"
                     /translation="MKICNDNFIKNFKNMINKCLDFIYPENISCIICDKSIKKTNTYS
                     ICKSCFKEMNFIQDGCMKCGKPIIRHSIEKEFIEECSYCFNKDFYFDKSISCIEYNDV
                     TKKIVLGLKYNQKTFMAKYIAQIMKEKLYLENIKFDYILFVPLHKKRLNKRGFNQAQK
                     IAFNLSKIVNIPLLDCISRKKYTRMLYKLNKKERKEELKNVFVVKDNVKLINNKNILL
                     IDDIFTTGLTTNEISKLLKLSGANKVFVLTLLTKANDNYIME"
     gene            13125..15038
                     /locus_tag="KR231_001806"
     CDS             13125..15038
                     /locus_tag="KR231_001806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HBH0004185.1"
                     /translation="MICLNKRQENLLTTLLLKEEFINVNKIANDFECSERTIRNDCKY
                     IDEWLSTFCNAYIKRKPNIGIKFSGDGTDKILVNQKLRGEVKRVNSELHKQVEILNLL
                     LCNNKKVTLNDLSNKLYINKNIVREEISKLSVALNNYNLNVSTKKGSGIYIGGDEKDI
                     RIMLVSFLFKYIDKYRLNIDEIEYFHIVDIIIVKNIMFTIEEDMDIRLTDISFKQLML
                     FLLINIIRIRLGNSLKVSNTKKELKLKMLILDIEDELKSNLSIVLNYEEKLFIESLIL
                     GMNKQINSSNIKKSLYLNEELASYTKKIINLVSEESGINFNNDILLYEQLICHLNVTM
                     HQMKSNVYLENPLLDNIKTKFCFLFTVISSSIEIELKGKQITEDEIGYLTLHFQTSLE
                     RKYSKRESNKKASIVCPFSFGVSMLLKVKIEKRFDNIKIIETLREEDLKRDNFNKTID
                     FIIAFQEYENIQKPIFITTPLFTDEDENKLKEFTNKIKEKDTSYKLMNRLMMSDYLIR
                     ELEHDDIYEAITYLTNLLIEKHYAEKEYLQSIITREKSYPTNVGKGILFPHGDMKYIK
                     QSVLCFARLKTPIRIRNGKDIKIILLLAYKKDDDRKVFRELFKEISNLTEDENMLDIL
                     SKCDIEKVKDILI"
     gene            15179..15487
                     /locus_tag="KR231_001807"
     CDS             15179..15487
                     /locus_tag="KR231_001807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HBH0004186.1"
                     /translation="MEEIVLKIIIHAGNAKSMLYEALDYAKENDFKKADELIENANEE
                     ILKAHKVQTELIQKEAGGDKSDISILLIHSQDHLMTCMSERNLIKEMIMLRKEIQKLK
                     "
     gene            15511..15837
                     /locus_tag="KR231_001808"
     CDS             15511..15837
                     /locus_tag="KR231_001808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBH0004187.1"
                     /translation="MKRKVYLFCSFGMSTSLLADKMQKVADEHNLPIEVEAFPIAEID
                     KIVEEKNPDCILLGPQVKYMLKELKPKFEAQGKLIDIINEVDYGTMNGEKVLKLAIKL
                     IKSKQA"
     gene            15876..17210
                     /gene="celB"
                     /locus_tag="KR231_001809"
     CDS             15876..17210
                     /gene="celB"
                     /locus_tag="KR231_001809"
                     /EC_number="2.7.1.205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIC"
                     /protein_id="HBH0004188.1"
                     /translation="MNRLERILMPLAEKIGKNKLLIAIRDGFLISSPLLIIGSLFLLV
                     ANFPIKGWNEFVGQIFGSDWAVKLQQPTVATFEVMTLLAVLGIGYSYAKQIDVDPIAS
                     AAVAIVAFFIITPFVIPYTPEGTESVYMVTGIPLGWMGSKGMFVGMITAITSVKLFAA
                     VVKKGWTLKMPDGVPPTVSKSFAALIPSAIVMVVFFLVKIAFEATPYGSIHEFIFKFL
                     QMPLLKLGNSLGAMAIAYIFLHLFWFFGINGSSVVGAVYNPILKILSAENLAAFQAGS
                     KIPNIITGQFQDMFATFGGAGSTLSLVIAMLLICKSKRIKSMGKLSILPGIFGINEPL
                     IFGLPIMLNPILLIPFAIVPTINIIIAYFCMSAGLVPLTNGVQLPWTTPIIFSGFLTT
                     GWQGAVLQVVLLILGIFMYIPFIKMLDKQYLREENATVEEEDDDISFDDLVL"
     gene            17221..17739
                     /locus_tag="KR231_001810"
     CDS             17221..17739
                     /locus_tag="KR231_001810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine/betaine/sarcosine/D-proline family
                     reductase selenoprotein B"
                     /protein_id="HBH0004189.1"
                     /translation="MKKIVMILDQIQAGAGGKEKSNIPPAGKSSPLGPGIMMEQFLNE
                     SKVIATLFCGDEFFVNNEEEVTSKMIAMVKKLNPDVVICGPSFNYENFSKMSAILSKN
                     INDKTDIPAFAAMSEENIDVINEYKNDICIVKTPKKGGIGLNDSLNNICKLAKAIANK
                     EDITLMKEEFCY"
     gene            17835..18794
                     /locus_tag="KR231_001811"
     CDS             17835..18794
                     /locus_tag="KR231_001811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N(4)-(beta-N-acetylglucosaminyl)-L-asparaginase"
                     /protein_id="HBH0004190.1"
                     /translation="MWGMIATWRMALEGITEASEHLEKGMEAGDAVELAVRRVEDYPF
                     YKSVGYGGLPNENCEVELDAAFMDGNTLDIGAVAGIRDYSNPVSIARKLSYEKVNNFL
                     VGIGAEDYAHKNGFERKNMLTDRAKLHYKKRKKETLDKGLSPYAGHDTVGMISLDKTG
                     KMCAATSTSGLFMKKRGRIGDSALSGSGFYVDSSIGGATATGLGEDLMKGCISYEIVR
                     LMKEGKHPQEACDIAVNELDKQLIKRRGKAGDLSLVAMNNKGEWGVATNIADFTFSVV
                     TKEESPTVYISNRVDGKTIHKVISNEWMEAYEARIKAPIEVSE"
     gene            18843..19895
                     /locus_tag="KR231_001812"
     CDS             18843..19895
                     /locus_tag="KR231_001812"
                     /EC_number="3.4.13.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Sapep family Mn(2+)-dependent dipeptidase"
                     /protein_id="HBH0004191.1"
                     /translation="MNIISNKIDELKEDLLSDIIDIVKIPSVKGESENGFPFGEKVGE
                     ALNKALEISEKLGFKVRNLDNYIGYAEHGDSDDYVCVIGHVDVVHEGDGWKHQPYKGE
                     ETNGRIYGRGVLDNKGPIMSALYGLYAIKELNLKLDKRVRIIFGTNEESGFEDIPYYL
                     EKEKAPIMGFTPDCKYPVVYGEKGMAKIRIKSKINYEEDVYLGFIENMSENVLVTYKE
                     LNIENSDTILDIKVKYDFSYKLKDVLDEIKASFPNSIDIEVISNFNPVYFDKESNLVK
                     KLQLAYERVTSLDGTPVTTNGGTYAKVMPNIVPFGPSFPGQKGIAHNPDEYMDIEDII
                     LNAKIFANAIYELAKE"
     gene            19898..20572
                     /locus_tag="KR231_001813"
     CDS             19898..20572
                     /locus_tag="KR231_001813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper homeostasis protein CutC"
                     /protein_id="HBH0004192.1"
                     /translation="MLEIIGMSVEDAKIIEDCGADRIELVSALTEGGLTPSFGLIESV
                     VNSVKIPVNVMIRHHAKSFVYSKEDISIMQKDISVVKEIGANGVVFGVLDKNNSIDEK
                     NLNVLLKCCDNLDVTFHRAIDESNTIDSVKILKDYDKITNILTSGGKGSIVDNIQMIK
                     NMMLSSNHIKILLGGGLNFNNIEKIKELTKASNFHFGTAIRINNSPFEDIDRQKLKQL
                     VNIISR"
     gene            21125..21676
                     /gene="raiA"
                     /locus_tag="KR231_001814"
     CDS             21125..21676
                     /gene="raiA"
                     /locus_tag="KR231_001814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009887979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome-associated translation inhibitor RaiA"
                     /protein_id="HBH0004193.1"
                     /translation="MNIIISGKQIELTDAIKNKIETKLSKLDNYIHPDTDVKVTVSAR
                     KARQKIEVTIATVNGPIIRAEDMQENLYTAIDVVYDKLSKQLKKYKKRLQDKHKDNKS
                     IRFQDAEINLADEQEDYGDENQELVIQRRKKFSVKPMSEEEAVLQMELIGHDFYMFKN
                     IDSDEIAVVYKRNNGGYGIIEHE"
     gene            21808..24483
                     /gene="secA"
                     /locus_tag="KR231_001815"
     CDS             21808..24483
                     /gene="secA"
                     /locus_tag="KR231_001815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecA"
                     /protein_id="HBH0004194.1"
                     /translation="MSFMDNLFNMADKKELKKFNKTVDIIDSLEPKFESMADSELKNM
                     TNIFKERLANGESIDDILPEAFAVVREVSKRVLGLRHYRVQMIGGIVLHQGRIAEMKT
                     GEGKTLVATAPVYLNALTGKGVHVVTVNDYLAKRDRDQMAKIYEFLGMSVGVIIHGQN
                     PKVRKEQYDCDITYGTNNEYGFDYLKDNMVIHKEQRVQRGLNYAIVDEVDSILIDEAR
                     TPLIISGPGDKSTHLYSDANTFVLTLKPDDYELEEKDKAVSLTASGIQKAEVYFNVDN
                     ITDISHTELYHHINQALRAHVIMKKDVDYVAKDGEIVIVDEFTGRLMFGRRYSEGLHQ
                     AIEAKEGLKIQRESKTLATVTFQNYFRMYKKLSGMTGTAKTEEEEFKAIYKMDVFQVP
                     TNKLMIREDLPDCVYKSEIGKFNAVAQEIIERHKVNQPILVGTVSIEKSELLSQILKK
                     KGIKHEVLNAKHHDKEAEIIAQAGRLGAVTIATNMAGRGTDIVLGGNPDFLTKREMRR
                     NGFKEEIVNRVDTPIEGIPVKGNEILFEAREEYEKLFEKFKQQTQEEQKQVVEAGGLA
                     IIGTERHESRRIDNQLRGRAGRQGDPGSSRFYIGLDDDLMRLFGSDRISGIVDKIGLE
                     EDMPIEHRILSKSIEGAQKKVEGKNFGIRKHVLQYDDVMNKQREIIYAERKRVLEGED
                     LQEQIQSMTHSIIEEAVTLYTQDKGFDEEGFKEHMYNLFLPKGSIEIPEIEKLNPVEI
                     TEKVYEIAMKIYTSKEEQVGYERMREVERVILLQAVDNHWIDHIDAMDQLRQGIGLRA
                     VGQQDPVIAYKMEGFDMFDEMNKHIKEDTVRYLFNITIETPVERKAVVDVENLSSPSD
                     GTLPTSKTVKKDEKVGRNDLCPCGSGKKYKNCCGR"
     gene            24498..25605
                     /gene="prfB"
                     /locus_tag="KR231_001816"
     CDS             join(24498..24572,24574..25605)
                     /gene="prfB"
                     /locus_tag="KR231_001816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_153309863.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 2"
                     /protein_id="HBH0004195.1"
                     /translation="MLKLQEYRHSMEQMASNLEELRVSLDIASLMKNIQINEEKMNKQ
                     DFWNDNEVAQRVLQENKSLKETLEEYESLKSLLEDIEVLIEIGLEEDDDSVERDIEKS
                     IESMEEKLSEMKIKTLLNGEYDKNNAILSINAGTGGLDAQDWAQMLLRMYIRWSESKG
                     YKVKLLDIISDPEAGIKTATILVEGTNAYGYLKSEKGVHRLVRISPFDPSGKRHTSFA
                     SIDVTPELDENIEVEINPSDLKIDTYRASGAGGQHVNTTDSAVRITHIPTGVVVQCQN
                     ERSQHLNKDRAMRLLMAKLIELKELEQKEKIEDIQGKYSQITWGSQIRSYVFQPYKLV
                     KDHRTNAEFGNVDSVMNGNIDLFINEYLKMNKIV"
     gene            25749..27890
                     /locus_tag="KR231_001817"
     CDS             25749..27890
                     /locus_tag="KR231_001817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011010799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding transcriptional accessory protein"
                     /protein_id="HBH0004196.1"
                     /translation="MDINQILKKEFNLRDEQINNTLKLIDEGNTIPFIARYRKEMTGE
                     MSDVTLREFYEKLMYLRNLQSRKDDVVRLIDEQGKLTDEITQNIEKAKTLQEVEDIYA
                     PYKQKKRTRATIAKEKGLEKLALSILENNLDNIEIEAKNYLDEEKEVLSIEDALKGAR
                     DIIAELVSDDAKIRKYIRELALREGMIVSKSATDEKSVYDMYYDYSEAVKSMPPHRVL
                     AINRGEKENFLKVKLEINNDKVLNYIINEYVNDKNFKNKEEIVSSIEDSYKRLIFPSI
                     EREIRNHLTEIAQERAISVFGKNVKSLLLQPPVKDKVVMGFDPAFRTGCKIAVVDKNG
                     KLLDYTTVYPTDPQNDVEGAKKVLKGLIEKYDIDIISIGNGTASRESETFVSEMIKEI
                     DNEVQYVIVSEAGASVYSASELANEEHPDINVSIRGAISIARRLQDPLAELVKIDPKS
                     IGVGQYQHDLNKKRLEEVLDGVVEDSVNSVGVDLNTASYSLLEHVAGISKTIAKNIIA
                     YREENGDFTSRAQLKKVKRLGPQAFTQCAGFMRILEGKNPLDNTGVHPESYDICKKMI
                     EIIGYSLDDVKNKNICEIDEKIKEIGLRELSEKLEVGQVTLKDIITEIKKPGRDPREE
                     GIKPILRTDVLKIEDIQEGMTLKGTIRNVVDFGAFVDIGIKNDGLVHKSEMSNSFVKD
                     PMSIVTVGDIVDVKVIGIDLNKKRVALSMKK"
     gene            28038..29204
                     /locus_tag="KR231_001818"
     CDS             28038..29204
                     /locus_tag="KR231_001818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HBH0004197.1"
                     /translation="MIFIKNGKINTITNGIIHGDILIDEGKIIEIGEDLIAPLDVEVI
                     DASNKLVFPGFIDAHTHLGLWEDGIGFEGADGNEETDPITPQLNPIDGINPMDRTFKE
                     AFEGGITSVCTTPGSANVMGGQCIAIKTCGKRIDKMVIKNPVASKIAFGENPKSCYGQ
                     DDKSPQTRMAIAALLRENLKKAEEYLEDIDMYESHDDEDCEKPEYDIKMESLIPVLRR
                     EIPFKAHAHRADDMFTAIRIAKEFNLKLTLDHCTEGHLIVDELVEEGFPVIVGPSLSE
                     RSKFELRNLTFNTAGILSNAGLDVCIMTDHPVIPVQYLPICAGIAVKHGMKEEKAIES
                     ITINPAKTLGIEDRVGSIEVGKDADLVIWDNSPLEIQSNVLYTIINGKVVYEKK"
     regulatory      29264..29381
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00050"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="FMN riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="flavin mononucleotide"
                     /db_xref="RFAM:RF00050"
     gene            29505..30110
                     /locus_tag="KR231_001819"
     CDS             29505..30110
                     /locus_tag="KR231_001819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HBH0004198.1"
                     /translation="MQNTAKRGNMISTRTLVVMSILSAISYLLMFIQAPIPGIFPDFL
                     KIDLSDIPAIFGGMSLGPFVGFGIVVVKNVLQAITATTTGGIGEFANILIGGSYVMIL
                     CYSYKRSGDLKGVLIGFVLGTISMTIIGSLVNYFVMLPLYGQLMGLDAIIGLGSAINP
                     QVHDLFTFVIWMIAPFNVLKAVILSLVTLPLYKKMGNVIKK"
     gene            30439..31479
                     /locus_tag="KR231_001820"
     CDS             30439..31479
                     /locus_tag="KR231_001820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4116 domain-containing protein"
                     /protein_id="HBH0004199.1"
                     /translation="MNLSKKIKKLFLDDKGYYFNSNWKDIHIGIYNTKLGDSLKYITN
                     EYIENLERVKYDYRELKNIENQTDGMCILAIRQNYKALEYVKNQTEELCLEAIKYNYK
                     ALEYVKEQTEYICLEAIKKDCNALKYVRNKTERLIIKVIRHSSNIDVVSILKALETQT
                     RRICLEAIKKDGRCLAYVREQSEELCIEAIKQNYKALKYVENQTEKMCIESVRQNGMA
                     LQYVNKQTDKICIEAVKQDGRSLQFVNNKTEEICINAIRYLNKKYNIKDVLSYIDKYT
                     EDICIEIVRQNGKMLMYIKNQTEKMCIEAVKENYKSLKYVKEQSERICKEALKQNHKA
                     KEYVKIAIDDCI"
     gene            31618..32070
                     /gene="tsaE"
                     /locus_tag="KR231_001821"
     CDS             31618..32070
                     /gene="tsaE"
                     /locus_tag="KR231_001821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     ATPase subunit type 1 TsaE"
                     /protein_id="HBH0004200.1"
                     /translation="MAKIYLENENKTREIGYKLGKLLKEGSVICLVGDLGAGKTTMTQ
                     SLADSLGIEDYITSPTFTIINEYEGKIPLYHFDVYRIGSSDEMYDIGYDEYVNSNGIC
                     IIEWANLIEDILPKEYLNIELRYKDDGREMILTPKGEFYKEIVEELIK"
     gene            32070..32786
                     /gene="tsaB"
                     /locus_tag="KR231_001822"
     CDS             32070..32786
                     /gene="tsaB"
                     /locus_tag="KR231_001822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     dimerization subunit type 1 TsaB"
                     /protein_id="HBH0004201.1"
                     /translation="MKILGMDTSSMAASVAVVEDDNLICEFTVNNKKTHSQKLMPMIE
                     NMLSMSDLSIKDMDLLAVCIGPGSFTGLRIGMATVKAMAHVNNIPIIAVNSLESLANN
                     INFCDRKICCILDAQKNQVYSAKYKFENGEMIELDGVDVVEFDALVDEIVSTNEEFII
                     VGEAVYKYKDKLENIKNIKIPSPANNVSNAGSLCSLALNKYNKNIDVHTCYTINPMYI
                     RKSQAEVQYDEKMKRLNNGR"
     gene            32776..33252
                     /gene="rimI"
                     /locus_tag="KR231_001823"
     CDS             32776..33252
                     /gene="rimI"
                     /locus_tag="KR231_001823"
                     /EC_number="2.3.1.266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009887996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal protein S18-alanine
                     N-acetyltransferase"
                     /protein_id="HBH0004202.1"
                     /translation="MEDNTKLIVDDIKIEEMTTEDIDEVFEVEKNCFEDYWSKESFRK
                     ELSNEVARYIVAKLNGKIVGYVGIWLILDEGHINNVAVHSDYRGKKIGDKLIKGIVDL
                     CKDNNIASMTLEVRASNKIAQNLYRKYGFKMGGIRKEYYSDNKEDAIIMWNQLKEV"
     gene            33258..34274
                     /gene="tsaD"
                     /locus_tag="KR231_001824"
     CDS             33258..34274
                     /gene="tsaD"
                     /locus_tag="KR231_001824"
                     /EC_number="2.3.1.234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     transferase subunit TsaD"
                     /protein_id="HBH0004203.1"
                     /translation="MSDIITLAIESSCDETAASVLKNGREVLSNIISTQIETHKKFGG
                     VVPEVASRKHVENIDIVVQEALDKANIGFNDIDHIAVTYGPGLVGALLVGLSYAKALA
                     YTLNIPLVGVNHIEGHLSANYIEHKDLKPPFITLIVSGGHTHLVEVKDYGKYEILGKT
                     RDDASGEAFDKISRAMNLGYPGGPIIDNLAKKGNKHAIEFPRAYLEEDSYDFSFSGLK
                     SSVLNYLNGKRMKNEEIVVEDVAASFQEAVVEVLSTKALKAVKEKGYNIITLSGGVAS
                     NSGLRAKITELAKDSGITVKYPPLILCTDNAAMIGCAGYYNFINGKTHDMSLNAVPNL
                     KINQ"
     gene            34571..37279
                     /gene="hpdB"
                     /locus_tag="KR231_001825"
     CDS             34571..37279
                     /gene="hpdB"
                     /locus_tag="KR231_001825"
                     /EC_number="4.1.1.83"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxyphenylacetate decarboxylase large
                     subunit"
                     /protein_id="HBH0004204.1"
                     /translation="MSQSKEDKIRSILEAKNIKSNFQNKENLSEFNEKKASKRAEDLL
                     DVYYNTLSTADMEFPYWYNREYRKSDGDIPVVRRAKALKSAFSHMTPNIIPGEKIVMQ
                     KTRHYRGSFPMPWVSESFFVAQGEQMREEAKKLASNTADELTKFGSGGGNVTESFGNV
                     VSIAGKFGMRKEEVPVLVKMAKEWVGKSVEDLGFHYEKMMPDYDLKENLMSTLICMFD
                     SGYTLPQGREVINYFYPLNYGLDGIIEMAKECKKAVAGNASGDGLIGMDRLYFYEAVI
                     QVIEGLQTWILNYAKHAKYLESIETDLEAKKEYSDLVEILEHIAHKQPRTFREALQLT
                     YTIHIASVNEDAISGMSIGRFGQILYPWYEQDIEKGLITKEEVIELLELYRIKITCID
                     CFASAGVNGGVLSGNTFNTLSIGGLKEDGSTGANELEELLLEASMRCRTPQPSLTMLY
                     DEKLPEDFLMKAAECTKLGSGYPAWVNNSNGTTFMMKQFADEGMTVEEARAFALGGCL
                     ETSPGCWKQLTLNGKTYSIAGGAGQSAGSGVHFIANPKILELVLMNGKDHRMNIQVFE
                     PHNKPLDTYEEVIEVFKDYYKQAINVLERANNIELDIWRKFDTSIINSLLKPDCLDKG
                     QHIGNMGYRYNATLNVETCGTVTMVNSFAALKKLVYDDKAFTIEEMKDAILNNFGFKD
                     ALEVGNYSMADQVKVDKTGKYDAIYKACLDAPKYGNNDLYADNILKNYEVWLSKVCEE
                     AQSLYAKKMYPCQISVSTHGPQGAATLATADGRLSGTTYSDGSVSAYAGTDKNGVYAL
                     FESATIWDQAVVQNSQMNLKLHPTTIKGQQGTKKLLDLTRSYLRKGGFHIQYNVVDSE
                     TLKDAQKNPDNYRQLMVRVAGFTQYWCELGKPIQDEVIARTEYEGV"
     gene            37283..37540
                     /gene="hpdC"
                     /locus_tag="KR231_001826"
     CDS             37283..37540
                     /gene="hpdC"
                     /locus_tag="KR231_001826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxyphenylacetate decarboxylase small
                     subunit"
                     /protein_id="HBH0004205.1"
                     /translation="MRKHSDCMNFCAVDATKGICRLSKQMINLDDAACPEIKVMPKCK
                     NCKNFVEANDEGIGKCVGLEKEDWVYSTLNAITCEGHVFNE"
     gene            37533..38483
                     /gene="hpdA"
                     /locus_tag="KR231_001827"
     CDS             37533..38483
                     /gene="hpdA"
                     /locus_tag="KR231_001827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxyphenylacetate decarboxylase activase"
                     /protein_id="HBH0004206.1"
                     /translation="MSSQKQLEGMIFDVQSFSVHDGPGCRTTVFLNGCPLSCKWCANP
                     ESWTVRPHMMFSELSCQYENGCTVCHGKCKNGALSFNLDNKPVIDWNICKDCESFECV
                     NSCYYNAFKLCAKPYTVDELVQVIKRDSNNWRSNGGVTFSGGEPLLQHEFLHEVLLKC
                     HEVNIHTAIETSACVSNEVFNKIFNDIDFAFIDIKHMDREKHKEQTGVYNDLILENIS
                     NLANSDWNGRLVLRVPVISGFNDSDENISDIISFMHKNNLVEINLLPFHRLGESKWIQ
                     LGKEYEYSDKGDVDEGHLGELQDIFLDNGIACYVGHETAF"
     gene            38798..39760
                     /locus_tag="KR231_001828"
                     /pseudo
     CDS             38798..39760
                     /locus_tag="KR231_001828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112760.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
     gene            complement(39859..>40584)
                     /locus_tag="KR231_001829"
     CDS             complement(39859..>40584)
                     /locus_tag="KR231_001829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HBH0004207.1"
                     /translation="YSLIILFFLTYSLLIVLKLLNLINNNEFIIINLILTFISSLSII
                     IYSSNKKNLYPIKNIKLGSLLIIYFMISVIVPTSFILILQGSQPNYSGIIKFIFTPIT
                     SLTTIYIFFSEEYAWRGFLQNIFFNKFGKKLGVIILGICWSLWHLPLIFTLYTPETPI
                     LGLILRSIHIVGISIFLGYLYIKTKNIWFCAIIHILNNSAFLITNSKESTITYHDILI
                     VSMVVLIFYVPFLFTKEYKNNLE"
BASE COUNT        16431 a         4260 c         7592 g        12301 t
ORIGIN      
        1 ttatagggat gacaatatct tatgcagata caagtataaa tactaaatac aatagattaa
       61 gtaaagctct tgaaatttca gaagcaaatt ttaaatttta taatgttaaa attaattctg
      121 ttataaatca taatttatca aataaagaat ttcataatat ttttatagaa ataattaaca
      181 atctaaagtt ggataaaaaa ggaataaatt ggaatcaaaa agggtctggc gataaaatac
      241 aattatgtgc tactataaaa ggtagcgata aagaaatttc tataaaagga ataaataaaa
      301 ataacaaaga aagttacata gtagttgaca tattggataa caaagtatat aaacataaag
      361 aggttattta tagtaacgta gaaaatgtgt taaataaata ttcatctcaa gtagatgtgt
      421 ctgcttgtat tgttggagaa tacacaaaaa ggttacaaaa caacaaatat gatgatattt
      481 tacaaaaaat attatataat atgagtgcta agcaaataga tgaagtgaaa gacgtaaact
      541 ttttatctat aacagcatat agtaaagtat taaatgatta tgaattagaa tatttagggg
      601 aaaaaattaa tttaaatata ggaattaaat ataatgagga cgacggaaga acactcatat
      661 atattgccac accaattata aaattagatt attaattatg aggagatcaa aaaatatggc
      721 taagataata gtaaaaaaga gtaatccact taaaggtagt gttaaaatag atggtgcaaa
      781 aaatgcagtt ttaccaataa tagcagcgac tttattagca aacgggaaat caacattaaa
      841 tggagtacca aatttaagag atgttcatgt tatatcagat ttattaagac atgtaggggc
      901 agaagttgaa tataaagaaa atacacttac tgttgatgca agtaatataa aaacttgtga
      961 agctccatat gagcttgtaa gaaagatgag agcttctttt ttggttatgg ggccattgct
     1021 tgctagattt aatagtacga aaatttctat gccaggagga tgcgctatag gaacaagacc
     1081 tatagattta catttaaaag gatttaaagc cttaggtgca aagatagaaa tggaccatgg
     1141 ttttgttgaa gcagcaacag aaaaattagt aggaaataaa ttatatttag atttcccatc
     1201 tgttggagca actgaaaaca taatgatggc agcttcttta gcagaaggga ctacaataat
     1261 agagaatgca gcagaagagc cagaaatagt agatttagca aacttcttga acgaaatggg
     1321 agcagatgtt aaaggtgcag gtactaatac tataaaaata aaaggtgtta aagagttaaa
     1381 aggagcagaa cataatgtaa ttccagacag aatagaagca gcaacttata tggttgcagc
     1441 agctatgaca aaaggtgata taactgttga aaatgtttta atggagcatt taaaaccagt
     1501 tgtagctaaa ttaagagaag ctggttgtga aataacagaa atggacaatt ctgtaagagt
     1561 tgtaggtcca aaagtattaa aaccaataga tataaaaact ttaccacatc caggatttcc
     1621 tacagatgtt caagcacaat ttatggctat gcttactgta gctaatggaa ctggtgtagt
     1681 tatagaaact gtttttgaaa acagatttat gcatgttgct gaatttaata gaatgggtgc
     1741 taatataaaa atagatggaa gaagtgcggt tgttaatggt gtagatgagc tacatggtgc
     1801 agcagtaaac gctactgatt taagagcagg ggcagccctt attttatgcg gtcttatagc
     1861 agaaggagaa actcaaatag gagaaatata ccatatccaa agaggctatg ttgatataga
     1921 taagaagata acagcattag gtggtcaaat cgaaatagta gaagattaat aattggttta
     1981 tagaagaaag ttataaatta atagggttgt tcatatactt aaatacaagg ttttaaaagc
     2041 taaggaggag agtatatgaa gaacccattg gttgttttgt taggatttgt gacttgctct
     2101 gtgttagttc catcacttat aactttagtt tcttataaaa atgtagaatt aactgaaaaa
     2161 gcagagagcc cagtatctat aaacaaaact attaaaaaaa gtgatattga agacaaaggt
     2221 aataaagaag aaaaaaatac agtgaactat gaaactgtaa ataaaaaagc accaattatc
     2281 aatgtatata atcatataac agggaaaacc gaaaagatgg acatggagaa ctatttatgt
     2341 ggagtactag ctggtgagat gtcttcagag tttgatatag aagccttaaa agctcaatct
     2401 gtagcagcta gaacatatgt agtatataaa caggaacatg gtaaatctag taaacataaa
     2461 aatgcagtag tatgtactga ttataaacat tgtcaagaat ataagagtta tgatactctt
     2521 aaaaaattaa atggtgaaga atggattaag aataaatatt ccaaaatcca agaagcagtt
     2581 agaggaacta aaggtcaaat aataacttat aacgataagg cgatacttcc tctttatttt
     2641 tctacatctt caggaaaaac agaaaatagt gaagaagtat tttctgcaaa atatccttat
     2701 ttaaagtctg tggaaagtcc ttatgataag tattccccta aatttgcgtc aacacttaaa
     2761 ataagcaaca cagattttgt taaaagtctt agaagggcat atagcactat tgtgatagat
     2821 gtgaataatt taagtaaaca agtttcaata actaaaagaa gtgatgccgg aactgtagaa
     2881 aaaataaaat taggaaataa agaattgact ggaaaagaca ttagaactgt ttttaaattg
     2941 aactctgcaa actttgacat aaaatttgga gaaggataca tagatttcgt ggtaaaagga
     3001 tatggtcatg gtgttggtat gagccagtgg ggagcagaag gaatggcaga agagggctat
     3061 aaatattatg atatattatc acattactat acagatacaa aaataaaaga tatatactaa
     3121 taattgtata aaatgccaaa aacacgtcaa taatccaaat gtagaaatat atttggaggt
     3181 gcaaaatgaa gaaaaagctg ttagaaaaag atggttttta tttatctttg tttgtatgtg
     3241 tttgtttatt agcagtaggt ggagtttggt ttacaaataa taatgtagat aaattggctt
     3301 ctaataaagg aattatggaa aatgctaata aagatagtga agaggaaata catttaattg
     3361 aaaaagacaa gaaagatgct atccctactg caacggattc aaaacaaaac ttagaaaaag
     3421 ctaagtcaaa agaggaaaat aaatcgagta caacaaaatt aaattacatt ggagataaag
     3481 taataagagg atattcagaa aaagaaccta gttattctaa aacacttgat gtttgggaaa
     3541 ctcataaagg tgtagatatt agttgtacta aaggcaaaga agtaaaatct ctattaaacg
     3601 gaatagtagt agatgtattt aatgatgaag aatatgggca atcagtcaaa ataaaaagtg
     3661 acaataacat tgtagtagta tattcaaatc tagataaaaa tgttagtgtt aagaaagaac
     3721 agaaggtaac agaaggacaa tctctaggta ctgtaggtag tacttctcaa atagaaagtg
     3781 aagaaggtat acatgttcat ttagaggcgt atagtggaga aaaatctata gacccaatga
     3841 gtctaattaa gtaaaagtat aacaagttta atcatatttg gttaagcttg ttatattttt
     3901 tggtgttttt acatatatat cattaaagct attatgtgag gggggtaatc tttgagatct
     3961 catatagagg aaagggccat agtggtagca aaatatatac ttgaaaaaaa cactacagta
     4021 agacaaaccg ccaagacatt tggagtaagt aaaagtacaa ttcataagga tgttacagaa
     4081 agattgaagg aaataaatcc atcccttgcc aaagaagtta aaaatgtgct ggacaaaaat
     4141 aaatcagaga gacatattag agggggatta gcaacgaaat taaaatatga gaaggaacat
     4201 aaaaaaatgt aggttaaaaa cctacttttt ttatttaatt aaattataaa aagaaatata
     4261 ttaagtaatt ataaatagca aaataataat actctcaaaa gatttatttt ctcttgatta
     4321 aagcgagatt tttgtatatg ctttattata ggagtattaa aataggctta taatataatc
     4381 taatattata aataaaggag ttgaaaaaat ggctggagct gatataggca tagatttagg
     4441 tactgcaaat gtgcttgttt atgttagtgg taagggaatc gttttagaag aaccgtctgt
     4501 tgtggcgata gacaacagaa cagattctgt tttagctgtg ggagaagaag ctaaaaagat
     4561 gatagggaga acaccaggta atatagtcgc tataagacct ttaagagatg gtgtaatttc
     4621 agattatgat gtaactgaga agatgttaaa atcttttata gataagatag ttgataaaaa
     4681 gggatttgga agatttttta tgccaagaat tatggtatgc gtaccaacag gtgtcacaga
     4741 agtggaaaag agagcagtag aagatgctac gagacaagct ggagctagag aagtatatat
     4801 aatagaagaa ccaatagcag cagccatagg agctggtgta gacatatcac agcctaatgg
     4861 taatatgatt atagatattg gtggaggtac tgtagatata gctgtaatat ctctaggagg
     4921 agctgttgta agtgaatcta taaaggttgg tggagataga tttgatgatg ctatagttaa
     4981 atatatgaaa aaacaacaca atcttcttat aggagaaaga acagcagaga aaatcaagtt
     5041 tgaaataggt tctgcattta agagagaaga agaaaaatat atgaagataa caggaagaaa
     5101 tttaattaca ggacttccta gttctataac tataaattca acagaaatgt tggaagcact
     5161 tagagaatgt gttgagcaaa tagtagttgc tactcatgct gttttggaaa aaacgcctcc
     5221 tgagttagca gcagatatag gagatgttgg tataataatg actggaggag gttcattatt
     5281 atatggatta gataaaataa tagaacagag aacaggaata actgttacaa tagcagatga
     5341 accattatct tgtgttgcaa aaggtacagg aatagcttta ggttcaatag acctacttga
     5401 aactggcggg tctttcaaaa gaaaataatt aggagagttt agaatgttaa atatagatga
     5461 aataaaaaaa ttaataccac atagatatcc ttttttatta gtggacaaga ttacagagct
     5521 agaagttggg aaaagagctg ttggtataaa gaatgtaaca gttaatgaac catttttcca
     5581 aggtcacttt ccagaatatc ctttaatgcc aggagtatta atagtagaag ctttagcaca
     5641 agtgtgtgga gtggcaatga tgtctgtaga ggaaaacaaa ggaaaactag gtgtatttgc
     5701 aggtatagat aaagttagaa tcaagagaga agtaagacca ggagatacat taactatgga
     5761 agttgaaatg acaactctta gaagaaatat agccaaggca gatgctaagg catatgttgg
     5821 tgaagaactt gtctgtaaag gggaattaat gtttgcctta gtagaaaaat aaaaacttga
     5881 aatataaaag taaaaaggta gataatttgg agtatttaat cagatactct aaaatatcta
     5941 cctttttata taaagaattt tatcatttag tttatattta gattaggtgg atactaataa
     6001 agccaaggct attgtttcag ctaagtctaa tataaagcta agacgtatat tattaaatga
     6061 aagtttatta ttttcatcaa ttttatctac aattcctact atagaataat ttcctatttg
     6121 aggtagtttt ttgccaacac cttttccggg caggataggt ccttctctaa tctgtatatt
     6181 acctatgtta ctctgcgacc ccaagcaagc atctatagcc aagaagttac cttgtatatg
     6241 tgtatttttt atagtatcta aagactcata tatatttaag gcgtgaatag ggttatctag
     6301 tgtaccgtaa acggggtatt taaagttact gttcttaagt attgttccaa ctaaagggcc
     6361 taaagtatca cctatagccc tgtctgttcc tatgcaaaca acaatcgtat tttcattaat
     6421 tatagttttt agaactgaac ttagcatctg tataacatca tcatcgctgt aatttacttt
     6481 agctaaatac aataggaaca cccccttcaa aaaaatatat gaataaaaag cattaaaaag
     6541 acctaacttt aaatttcaga tagatagaaa attttatttg tcttacaaaa aaaggaatag
     6601 aaaaaatatg actaaaaata ttgacaaaat tttaaaaaaa tagtaagcta gtaaagtaaa
     6661 acaaaactta aatcttgatt accttatcaa gagaggctga gggataggcc ctgtgaagcc
     6721 cagcaaccac ccaaatggga aaaggtgcta attcctacaa gacaaaagtc ttgaaagatg
     6781 aggtcagtta attagtatgt aattacgatt attaacctct tcttataaag gagaggtttt
     6841 ttattttgag taaatttcta aaattaaaaa taaggtaaaa cctataataa aaactaagaa
     6901 taaataaggg ggaataaaaa tggcaagaca tttatttacg tcagaatcag ttacagaagg
     6961 acatcctgat aagatatgtg accaaatatc agattcaata ttagatgcat tattagaaaa
     7021 agacccacaa tctagagtag cttgtgaaac tacagttact actggtttag ttttagtagc
     7081 aggagaaata agtacatctg cttatgtaga cattcctaaa ttagtaagag aaacagtaag
     7141 agaaattgga tatacaagag caaaatatgg atttgattgt gatacttgcg cagttataac
     7201 ttctattgat gaacaatctg gagatatagc tatgggagtt gatgaaggcc tagaaagtaa
     7261 gactggagaa gagatagaag aagaaataga aaaagttgga gctggagacc aaggtataat
     7321 gtttggattt gcatgtaatg agactccaga attaatgcct cttccaatat ctttggcaca
     7381 caaattatca agaagactta cagaggttag aaagactggt ctagttgatt atttaagacc
     7441 agatggaaaa actcaagtta ctgttgaata tgaaggaagt aaagctgtaa gagtacatac
     7501 agttcttata tcagctcaac attgtgaaac agtatcaaat gataaaataa gagaagattt
     7561 aattaatcat gttattaaag aagttatacc agcagaatta cttgatgaag atactaaaat
     7621 ttatataaat ccaacaggaa gattcgttat aggaggacca caaggagata caggtcttac
     7681 aggaagaaaa ataataatag atacttatgg tggatattct agacatggtg gaggagcttt
     7741 ctcaggaaaa gaccctacaa aggttgatag atctgctgct tatgcagcta gatatgttgc
     7801 aaaaaatatt gttgcggctg gtcttgcaga caaatgtgag atagaacttg catatgctat
     7861 aggtatagct agaccattat ctatatttat agatactttt gggacaggca aagtttcaga
     7921 agaaaaactt gttgaattag taaataaaca ctttgattta agaccaggag ccataataag
     7981 agacttagat ttaagaaagc ctctttataa aaaggttgct gcttatggtc actttggtag
     8041 aactgatata gatttacctt gggaaagaac tgacaaggtt gagcagttaa gaaaagatgc
     8101 tttaggtgaa taatttttaa ctaaaaagct gttagaatgt aattttacga ttactttcta
     8161 acagcttttt tattatgagt taaatatttt taataaatgt taatttatca tcatataatg
     8221 aataaacagt atttaatctg gtcaatacat tttatataat actatactaa atttatgcat
     8281 attatgggat atatgttaaa ggatggttaa gaatgtgtta actaatgtta aataattaaa
     8341 aatatattga aatatcataa taatgagtct aatataatct taataaactt acactttaaa
     8401 aataatttta attgggggga gtagtgtatg tcaggcaaag taaatattaa aacggttata
     8461 agttttgctg gagcttatgt tgctactgta ataggttctg gatttgcaac tggtcaagaa
     8521 atactgcaat tttttacatt ttatggatat gctggtatta taggtggaat aatctctatg
     8581 gtactatttt catggtttgg agcagaggtt atagataagg gaagagaatt gaaacttaag
     8641 gagccaataa aaatttatca agtatattgt ggaaaatatc ttggaacatt ttttgaatgg
     8701 tttggtccat tgtttttatt tggaacatta gtaataatga ttgcaggagc aggagctaca
     8761 ttatcagagt actatggatt aaatccatat gtaggtagga ttggtatgac aatcgtttcc
     8821 ctaataactg tttcattagg tttgacaagg ctttctaaaa tactaggtaa tataggacct
     8881 ataataataa tatttacact tttagtagga gcaattagtt tatttagcaa tattgatgct
     8941 ttatcaaatg ctggaaatat ggttgatagt ttaaatatta aaactgctac atcaaatgga
     9001 tatttctcag gagtacttta tacttgttat aatgtaataa tagtaataac attcttgaca
     9061 ggaatgggag cttctgcagt aaataagaaa gatgctgtgt ggggtggtat agtaggtgga
     9121 gtagcactta tggcagcagc tataatgatg aatttggcat tactttcaga cataggaaat
     9181 atatacacaa aagagatacc agcactttac ttagctgata agatatctcc aataataggt
     9241 attttattct cagtagtact tttactagga atatacacta cagctgtacc attgttatgg
     9301 tcagtaacta accgatttgt agaagatgac caccctaaat ttaaaattat aacaatagta
     9361 gtaagtatat tagcttgtat aggaggtcta ctgccatttg ataagttagt aggtacacta
     9421 tatccatata caggttacat gggaatttta attttactat gtatgcttta tagaagaatt
     9481 actaaaactg aggggtacaa ggagaataaa tctgaaataa gctagtactg taatatactt
     9541 atgaaattta atttatactc taaatatgga gtaattaaaa taaaatagct atttaaatat
     9601 ggtacctgta tttcatggta ccatatttta tggatgcaga ttttttttgt ttctgataaa
     9661 atgtataata gttggaaatt acgttaagta taaaaatata aaacttttct acgattatca
     9721 tagttttaat atataaaatt atactaacat ttaaatggag cgattattag tatttttagg
     9781 agataaaaat ggaaaaatta gaaggaatga taagtgaaat agtctttaaa aacgaagata
     9841 atggttatac aatagctcat ctggtaaatg aaaatgatga aattgtcgtt gtaggatgta
     9901 tgcctacttt ggcaattgga gaaagcatag aagttgaagg aaagtgggta aaccataaga
     9961 tttatgggac tcaatttgaa gtgaatagtt ttatgccagt aacaccatca tccttagaag
    10021 gaatttatgt ttacttatct tctggaatga tacatggtat tggtgaaaaa atggctaaaa
    10081 gaataattga taagtttggt gtagatacgt tagaggtgat acaaaattca ccagaaaaac
    10141 tacaagaagt agaaggtata gggagtaaaa aagtaaaaca aatagtaaaa agttatgaag
    10201 aagacagaga attgagaaat ataataatac agctatctcc ttttggaata acaccaaatt
    10261 actgcctaaa aatatataaa aaatataaaa gcagtgcaat agaagttata aataaaaacc
    10321 cataccaact tgctgaagat ataagaggaa ttggatttaa agtagctgat agtatagcaa
    10381 ataaaattgg tatagataaa aattctaagg atagaatttg tcagggaatc ttatacactt
    10441 taaataaatc tttaagtaat gggcatacat atttaccaga gcatgttcta atacaagatt
    10501 cggaaaaatt attggagcta aatggagaaa taataaaaga gtgtgtaatg atgctagttt
    10561 ataatcaaaa aatacatgta gagaaagtaa acaatgaaaa tcttatatac cttatgccat
    10621 actatttagc tgaaaatgga gtatgtagtc aaatagtaaa attatcacag tatgaatttg
    10681 aagacttaaa aatagatata gataacgaga ttaatgtttt agaagaagat aagaaaatta
    10741 agttagcaga aaaacaaatt ttagcagtca aagaatctgt taatagtggc gtattaatta
    10801 taaccggtgg tccaggaact ggtaaaacaa ctaccattaa tgctatcata gatatatttg
    10861 aaaataatgg taaaagcgtg actttggcag ctccaacggg aagagcagca aagagaatga
    10921 gtgaaacttc taataaagaa gcaaaaacta tacataggtt gctagaaatg ggattttcaa
    10981 cagatgatga tttaactttt tttaaggatg aagaagaccc aataaattca gatgtaataa
    11041 ttgttgatga ggtatcaatg gtagacatta tcttaatgta caatttactt agagctataa
    11101 agttaggaac aagagtaatt ttagttggag atagtgacca attaccttct gtaggtgctg
    11161 gaaatgtact taaggatatg attaattcta atattataaa tgtagttaaa ttaaatgaaa
    11221 tatttagaca agcgcaagaa agtatgataa ttgtaaatgc ccataagata aacaatggag
    11281 aaccacttta tctaaataca aaaggtaaag atttcttttt tataagaaaa tcaactaatg
    11341 aagaaatttt aaatgaaata ataggattgg ttaatgaaag attacctaaa ttttataaag
    11401 ttgataaatt aaaagatata caagttttat cctcaatgag aaaaggtgaa ttgggagtta
    11461 ctaatctcaa tatagagtta cagaagtatc ttaacaaaaa agaaaaattt aaagttgaag
    11521 aaagtttttc taaaagatta tttagagttg gcgataaggt aatgcaagta aaaaataatt
    11581 atacaaaaaa atgggaaaca gaagaccaaa aagaaagtgg agaaggtatc tataatggag
    11641 atataggata tgtttatcac atagataaag ataaaaaaac tatttatata ttatttgacc
    11701 agactaaaat tgtatcatac ctatatgatg aattagatga aattgaccat agtttttgta
    11761 caacaataca taaaagccaa ggaagtgaat ttccagttgt agtattgcca atagcttggg
    11821 ctcctcctat gttacttagc cgtaatttat tatatacagc agtaacaaga gcaaaaaaat
    11881 tagttgtatt agttggagat gtgaaatatc ttgaatatat gataaaaaat aatagagtta
    11941 atcaaaggta ttcaaattta ggatataagc taaataaatt taagcaagaa gggctgttga
    12001 tagaataaat atgaaaatat gcaatgataa ttttattaag aattttaaaa atatgattaa
    12061 taaatgtttg gattttatat atcctgagaa tataagttgc ataatttgtg ataaatccat
    12121 aaagaaaaca aatacttatt caatatgtaa aagttgtttt aaagaaatga attttataca
    12181 agatggttgc atgaagtgtg gaaaaccaat aatacgtcat tcaattgaaa aagaatttat
    12241 tgaagaatgt agttattgtt ttaataaaga cttttatttt gataaatcaa tatcttgtat
    12301 tgaatacaat gatgtgacaa aaaagatagt gctagggctg aagtataacc aaaaaacctt
    12361 tatggctaag tatatagctc aaataatgaa agaaaaatta tatttagaaa acataaaatt
    12421 tgattatata ttatttgttc cacttcataa aaaaaggcta aataaaagag gttttaatca
    12481 ggcacaaaaa atagcattta atttaagtaa aatagtaaat attccattat tggattgtat
    12541 aagtagaaaa aaatatacaa gaatgctata taaattgaat aagaaagaac gaaaagaaga
    12601 attaaaaaat gtatttgttg ttaaagacaa tgttaaatta ataaataata aaaatatact
    12661 tttaatagat gatatattta ctactggtct aacaacaaac gaaatttcta aacttttaaa
    12721 gttatcgggt gctaataagg tttttgtatt gactctactt acaaaagcaa atgataatta
    12781 tattatggaa taatcttata tattgacaat tttaatttaa aatattaaaa tgaataagtg
    12841 atatttaggt ctgtggttga aagtccaagc cagtcgcagg caaagggatc cacgtaagtt
    12901 aacactaaaa attgggttaa tgatcatggt gcggcttaga agtaagacct accgataata
    12961 aaatcgagag agagtagtag tgcggcgaac ccaagcgaac cctccagtag gcgagtgtgg
    13021 ggtcaaaaac caggtcagct aaatatcgta ttaaaaggga gctagcatac ctttatgtat
    13081 agctcttttt tatatataat aaatttaggt tgagtcataa agaggtgata tgtttgaata
    13141 aaagacagga aaacttatta acaacgttgc tattaaaaga agagtttata aatgttaata
    13201 agattgccaa tgattttgag tgttcagaaa ggacaataag aaatgattgc aaatatattg
    13261 atgaatggtt atctactttt tgtaatgctt atatcaaaag aaaacctaat attggaatta
    13321 aatttagtgg agatggaaca gacaaaatac tggtaaatca gaagttgcga ggtgaagtta
    13381 aaagagtaaa tagtgagctt cataagcaag ttgagatatt aaatttacta ctttgtaata
    13441 ataaaaaagt tactttaaat gatttatcta ataagttgta cataaataaa aatattgtca
    13501 gagaagaaat aagtaaatta tcagtggcat taaataatta taatttaaat gtctcgacta
    13561 aaaaaggcag tggtatatat attggagggg atgagaaaga cataagaata atgttagtat
    13621 cattcttatt taaatacata gataaataca gattaaacat agatgaaata gagtacttcc
    13681 atatagtaga tataataatt gtaaaaaaca taatgtttac tatagaggag gatatggata
    13741 taagacttac agatatatca ttcaagcaat tgatgctatt tttacttata aatataatac
    13801 gaataaggct aggaaattct ttaaaagtat caaatactaa gaaagagctt aagctaaaaa
    13861 tgctgatatt agatatagaa gatgaattga aatctaattt atccatagta ttaaattatg
    13921 aagaaaaatt gtttatagag tctttaatat tgggtatgaa caaacaaata aatagtagta
    13981 atattaagaa atctttatat ctaaatgaag aattagcaag ttatacaaaa aaaattataa
    14041 atttagtatc agaagaatcc ggaataaatt ttaataatga tatattactt tatgaacaat
    14101 taatatgtca tttgaatgtt acaatgcacc aaatgaaaag caatgtttac ttagaaaatc
    14161 cacttttaga taacataaaa actaaatttt gttttttatt tacagtaata tcaagttcaa
    14221 tagaaattga attaaaagga aaacaaataa cagaagatga aattggttat cttacacttc
    14281 actttcaaac ctctctagaa agaaaataca gcaaaaggga atcaaataaa aaggcaagta
    14341 ttgtatgtcc atttagtttt ggagtaagca tgctattaaa agtaaagata gaaaagagat
    14401 ttgataacat aaaaattatt gaaacattaa gagaggaaga tttaaaaaga gataacttca
    14461 ataagactat agattttata attgcatttc aagagtatga aaatatccaa aaaccaattt
    14521 ttataacaac accattattt actgatgagg atgagaataa acttaaagag ttcacaaaca
    14581 aaataaaaga aaaagacact tcatataaac ttatgaacag attaatgatg tctgattatt
    14641 taataagaga gttagaacat gatgatattt atgaagctat aacatattta actaatttat
    14701 taattgaaaa acattatgca gaaaaagagt atttacaatc tattataaca agagaaaagt
    14761 catatccaac caatgttgga aaaggaatat tattccctca tggagatatg aaatatataa
    14821 aacaatctgt tttatgtttt gcaaggttaa aaacaccaat aagaattaga aatggaaagg
    14881 atataaagat tatacttttg ttagcatata aaaaagatga tgatagaaaa gtatttagag
    14941 aattatttaa agaaatatct aatttaacag aggatgaaaa tatgctagat attctaagta
    15001 aatgtgacat tgaaaaagta aaagatattc ttatataaaa ttcatagtga actatggata
    15061 agcacaaaat tttccatgtg atggaaaaag ttgtgcatgt ttttttgttt ttataagata
    15121 ttatatgttt gtaaggtata aataatctaa aagtagagaa gcaacttagg aggaaaaaat
    15181 ggaagaaata gttttaaaga ttataattca tgctggaaat gcaaaatcta tgctttatga
    15241 agcacttgac tatgcaaagg aaaacgattt taaaaaagca gatgaattaa ttgaaaatgc
    15301 aaatgaagaa attttaaaag cacataaagt acaaactgaa cttatacaaa aggaagctgg
    15361 gggagataaa tcagatatat ctattttatt gattcactct caagaccatt tgatgacttg
    15421 tatgagtgag agaaacctta taaaagaaat gattatgtta agaaaagaaa ttcaaaaatt
    15481 aaaataaaaa aattaagggg gatttaaaaa atgaaaagaa aagtatattt attttgtagc
    15541 tttggtatgt caacaagttt acttgcagat aaaatgcaga aggtagcaga tgaacacaat
    15601 ttaccaatag aagtagaggc atttccgata gcagaaattg acaaaatagt tgaagaaaaa
    15661 aatccagatt gtatattact aggaccacaa gttaaataca tgctaaagga attaaaacca
    15721 aagtttgaag ctcaaggaaa acttatagat ataatcaatg aagttgatta tggaactatg
    15781 aatggggaaa aagtattaaa actcgctata aagctaataa aatccaaaca agcgtagaat
    15841 tatagtaaaa aataatagga aatgagggta gatagatgaa tagattggaa agaatactta
    15901 tgccattggc tgaaaaaata ggtaaaaata aattattaat tgcaattaga gatggttttt
    15961 taatatcatc accattatta ataataggtt cattattttt attagtagca aattttccta
    16021 taaaaggatg gaatgaattt gtaggtcaaa tttttggttc agattgggct gtaaaattgc
    16081 aacaaccaac tgtagcaaca tttgaagtaa tgactctact tgcagtttta ggaattggat
    16141 attcttatgc aaagcaaata gatgtagacc caatagcatc agcagcagtt gcaatagttg
    16201 ccttttttat aataacacca tttgtaatac catatacacc agaaggaaca gaatcagtct
    16261 acatggtaac aggtatacca ctaggttgga tgggctctaa gggaatgttt gtaggtatga
    16321 taacagcaat aacctctgta aaattatttg ctgcagttgt aaaaaaagga tggacattga
    16381 aaatgccaga tggagttcct ccaaccgtat caaaatcatt tgcagcatta ataccaagtg
    16441 caatagttat ggtagttttc tttttagtta agatagcttt tgaagctaca ccatatggaa
    16501 gtatacatga atttatattt aagtttttac aaatgccatt attaaaatta ggaaatagtt
    16561 taggtgctat ggcaatcgct tatatattct tacatttatt ctggttcttt ggaataaatg
    16621 gaagtagtgt tgttggggct gtgtataatc caatattaaa aattctatca gctgaaaatt
    16681 tagctgcttt tcaagctggt tcaaaaatac caaacataat aacaggtcaa ttccaagata
    16741 tgtttgcgac atttggtgga gcaggtagta cactatcatt agtcatagct atgttattaa
    16801 tatgtaaaag taaacgtata aagtcaatgg gaaaactatc aattttacca ggaatatttg
    16861 gtataaatga gccattgata tttggtctac caataatgct taacccaata ctattgatac
    16921 catttgcaat agttccaaca ataaatataa taatagctta tttctgtatg tcagcaggat
    16981 tagtgcctct tacaaatgga gttcagttac cgtggacaac tccaattata ttctctggtt
    17041 ttttaacaac aggatggcaa ggtgcagtct tacaagtagt gcttcttata ctaggaatat
    17101 ttatgtatat accatttata aaaatgctag ataagcaata cttaagagaa gaaaatgcaa
    17161 ctgttgaaga ggaagatgat gatatatctt ttgatgattt agtattatag gaggaagatg
    17221 atgaagaaaa tagttatgat attggatcaa atacaagctg gagctggagg aaaagagaaa
    17281 agtaatatac ctcctgctgg aaaatcaagc ccattaggac caggtataat gatggagcaa
    17341 tttttaaatg aatctaaggt aatagctacc ttattttgtg gggatgaatt ttttgtaaat
    17401 aatgaagaag aagtaactag taagatgata gctatggtaa aaaaattaaa ccctgatgta
    17461 gtaatctgtg gaccaagctt taattacgaa aacttttcta agatgtcagc aatactgtct
    17521 aaaaatataa atgataaaac agatatacca gcttttgcag ctatgtcaga agaaaatata
    17581 gatgtgataa acgaatataa aaatgacata tgtatagtta agactccaaa aaaaggtgga
    17641 attggtctta atgattcatt aaataacata tgtaaattgg caaaagcaat agcaaataaa
    17701 gaagatataa ctttgatgaa agaagaattt tgttattaat aagagtatta attattagta
    17761 agtttaaata ttatactatt tataataagc atacattagt aaaatctata taatttaagg
    17821 aggggaattt taacatgtgg ggaatgatag cgacatggag aatggcccta gaaggaataa
    17881 ctgaggcatc agaacattta gaaaaaggca tggaagcagg tgatgctgta gagcttgctg
    17941 taagaagagt tgaagactat ccattctata aatcggttgg atatggtgga cttccaaatg
    18001 aaaattgtga ggtagaactt gacgctgcat ttatggatgg taacacatta gatattggag
    18061 cagttgctgg tataagagat tattctaatc ctgtcagcat agctaggaag ttaagttatg
    18121 agaaggtaaa taatttttta gttggaatag gtgctgaaga ttatgctcat aaaaatggat
    18181 ttgaaagaaa aaatatgttg actgatagag cgaagttaca ttataaaaag agaaaaaaag
    18241 agactttaga caaaggatta agtccatatg ctggtcatga tactgttggt atgatatctt
    18301 tagacaaaac tggaaaaatg tgtgcagcta catcaacaag tggattgttt atgaagaaaa
    18361 gaggtagaat aggagattct gcactatctg gttcaggatt ctatgttgat agtagtatag
    18421 gaggagctac agctactggt ttgggagaag atttaatgaa gggatgtata tcttatgaga
    18481 tagttagact tatgaaagaa gggaagcatc cacaagaagc atgtgatatt gcagtaaatg
    18541 aacttgataa acagcttatc aaaagaaggg gaaaagctgg tgatttatca ttagttgcca
    18601 tgaataataa aggtgaatgg ggagtagcta caaatatagc tgattttact ttttcagtag
    18661 taactaaaga agaatctcct actgtatata tttcaaatag agtagatgga aagactatac
    18721 ataaggttat atcaaatgag tggatggaag catatgaggc tagaataaaa gcaccaatag
    18781 aagtaagtga gtaaagtagt ggttacataa ttaaaataga gttttataat aaggagattt
    18841 ttatgaatat cataagtaat aaaatagatg agttaaaaga agatttatta agtgatatta
    18901 tagatattgt aaaaatacct agtgtcaaag gggagtcaga aaatggcttc ccttttggcg
    18961 aaaaagtagg ggaggcactt aataaagcat tagaaatatc agaaaaattg ggatttaagg
    19021 ttagaaactt ggataattat attggttatg cagagcatgg agatagtgat gattatgttt
    19081 gtgtaattgg acatgtagat gttgtacatg aaggagatgg ttggaagcat cagccttata
    19141 agggagaaga aactaatgga agaatttatg gacgaggagt actagacaat aaaggaccta
    19201 taatgtctgc cttatatgga ttatatgcta ttaaagaatt aaatttaaaa ttagataaga
    19261 gagttagaat aatatttggt acaaatgaag aaagtggatt tgaagatata ccatattatt
    19321 tagaaaaaga aaaagcacct attatgggat ttacaccaga ttgtaaatat cctgttgtat
    19381 atggtgaaaa aggcatggca aagattagaa taaaaagtaa aatcaattat gaagaagatg
    19441 tatacttagg ttttatagaa aatatgtctg aaaatgtgct tgttacatat aaagaactga
    19501 atatagaaaa tagtgatact atattagata taaaggtaaa atacgatttt agttataaat
    19561 tgaaagatgt attggatgaa ataaaagcta gttttccaaa tagtatcgat atagaggtaa
    19621 tttctaattt taatcctgta tattttgata aagagagtaa tcttgttaaa aagcttcagc
    19681 tagcttatga aagggttaca tcattagatg gaactccagt aacaactaat ggaggtacgt
    19741 atgcaaaagt aatgccaaat atagttccgt ttggaccttc atttccagga caaaaaggaa
    19801 tagctcataa tcctgatgaa tacatggata tagaagatat aatattaaat gcaaagatat
    19861 ttgcaaatgc aatatatgaa ttagcaaagg agtagttatg ttagaaataa taggaatgtc
    19921 agtagaagac gctaaaatta tagaagattg tggtgcagat agaatagagt tagttagtgc
    19981 tttaactgaa ggtggattga caccaagttt tggtcttata gaaagtgttg ttaacagtgt
    20041 aaagatacct gtgaacgtaa tgataagaca tcatgcgaaa agttttgtat acagtaaaga
    20101 agatataagt ataatgcaaa aagatataag tgtggttaaa gagattggtg ctaatggagt
    20161 tgtatttggt gtattggata aaaacaatag tatagatgag aaaaatctaa atgttttatt
    20221 gaaatgttgt gataatcttg atgttacatt tcatagagca atagatgaat caaatacaat
    20281 agatagtgtt aaaattttga aggattatga taaaattacg aatatattaa catcaggagg
    20341 gaaaggaagt atagttgata acatacaaat gataaagaat atgatgctta gttctaatca
    20401 cataaaaatt cttttaggtg gaggtcttaa ttttaataat atagaaaaga taaaggaatt
    20461 aactaaggca agtaattttc attttggtac agcgattaga ataaataaca gtccttttga
    20521 agatatagat agacaaaagc ttaaacaact cgtaaatata atttcaagat agtatatgaa
    20581 tataaaatac ttagtttaaa taaagagagt aagttaatta taatttgggt atatgaatgt
    20641 taataggtat taaatatgaa attattgttg agtatgcttt ataactttta agtagtttta
    20701 aatataaata atgaaagaaa agatagatta tggaggtttt agagggttta tatttattaa
    20761 aaaattataa aggtatattg gcatataata cacataattt cctaaaatta ccatcttatg
    20821 acatgaattc acatattaat aaacaattaa tggagatttt tgtggataga aataggagta
    20881 aaaatagctt taaataaaca aaaacaagag ttattaacag ttttatccac attatccaca
    20941 ggtgtttgta ataatattaa tccacataag tatcaatgta actaaaaatg ataaataatt
    21001 ctatcaattg aatagaaaaa atcataaaag taaataataa aaagaggatt atgagagttc
    21061 gtgtagaata tattattaaa gtataaattt tcttatactg gcataattga agggagatgt
    21121 atttatgaac ataattatat ctggaaaaca aatcgaatta actgatgcaa taaaaaataa
    21181 aatcgaaact aaactaagta agttagataa ttacattcat ccagacactg atgtaaaagt
    21241 tacagtaagt gcgagaaaag caagacaaaa aatagaagta acaatagcta ctgtaaatgg
    21301 tcctataatt agagcagaag atatgcagga aaatttatac acagctatag atgttgtata
    21361 tgataaatta agtaaacaat taaaaaaata taaaaagaga ttacaagata aacataaaga
    21421 caacaagagt ataagattcc aagatgcaga gataaatcta gctgatgaac aagaggatta
    21481 tggggatgaa aatcaagaat tagtaattca aagacgtaag aaatttagtg ttaagccaat
    21541 gagtgaagaa gaagctgtat tacagatgga attaatagga catgattttt atatgttcaa
    21601 gaacatagat tcagatgaaa tagcagtagt ttataagcgt aataatggtg gatatggtat
    21661 aatagaacat gaataaagca atttagattt aatcatatta gctatcgata aataaattat
    21721 cgatagcttt ttaaattaat attaaaagta tagtttttat ggtaaaatga ataatagtac
    21781 aataaagaac gaggagagat gtaaaatatg agctttatgg ataatttatt caacatggca
    21841 gataaaaaag aattaaaaaa gttcaataaa actgttgata taatagattc attagaacct
    21901 aaatttgaat ctatggcaga ctcggaactt aaaaatatga caaatatatt taaagaaaga
    21961 ttagcaaatg gtgaaagtat agatgatata cttccagaag cttttgcagt agttagagaa
    22021 gtttctaaga gagtgttagg acttagacac tacagagttc aaatgattgg aggtatagta
    22081 ctacatcaag gaagaatagc agaaatgaaa acaggtgaag gtaaaacttt ggttgcaact
    22141 gctcctgttt atttgaatgc gcttactgga aaaggtgtac atgttgtaac agtaaatgat
    22201 taccttgcaa aacgtgatag agaccaaatg gcaaaaatct atgagttttt aggaatgagt
    22261 gtaggcgtta ttatacacgg tcaaaatcca aaagttagaa aagaacaata tgattgtgat
    22321 ataacttatg gtacaaataa tgaatatgga tttgactatc taaaggacaa tatggtaata
    22381 cacaaagagc aaagagttca aagaggatta aattatgcta tagtggatga ggttgactct
    22441 atactaatag atgaggctag aacaccactt atcatatctg gacctggaga caaatcaact
    22501 cacttatatt cagatgcaaa cacatttgtt ttaaccttaa aaccagatga ttatgaatta
    22561 gaagaaaaag ataaggctgt atctctaaca gcatcgggta tacaaaaagc agaagtgtat
    22621 tttaatgttg ataatataac agatatatct catacagaat tataccatca tataaatcaa
    22681 gctttaagag cacatgtaat aatgaagaaa gatgttgatt atgttgctaa agatggagaa
    22741 atagtaatag tagatgagtt cacaggtaga cttatgtttg gtagaagata ttcagaaggt
    22801 ttacatcaag caatagaggc taaagaaggt cttaaaatac aaagagaatc taaaacacta
    22861 gctactgtaa cattccaaaa ttattttaga atgtacaaaa aactttctgg tatgactggt
    22921 acagcaaaaa cagaagaaga agagtttaaa gcaatctaca aaatggatgt tttccaagta
    22981 cctactaata agcttatgat aagggaagac ttaccagatt gtgtatacaa aagtgaaata
    23041 ggtaaattta atgctgtagc acaagaaata attgaaaggc acaaagtcaa tcaaccaata
    23101 cttgtaggta cagtatcaat agaaaaatca gaattattat cacaaatact aaagaaaaag
    23161 ggcataaagc acgaggtatt aaatgctaag catcatgata aagaggcaga aataatagca
    23221 caagctggta gacttggagc tgttacaata gctactaata tggctggtcg tggtacagat
    23281 atagttctag gtggaaatcc agacttttta actaagagag aaatgagaag aaatggattt
    23341 aaagaagaaa tagtaaatag agtagatact ccaatagaag gtatacctgt aaaaggtaat
    23401 gaaattctat ttgaagctag agaagagtat gaaaaactat ttgaaaagtt taagcaacaa
    23461 acacaagaag aacaaaaaca agttgtagaa gcaggtggac ttgctataat aggtacagaa
    23521 agacacgaat ctcgaagaat agataaccag ttgagaggtc gtgctggacg tcaaggtgac
    23581 ccagggagtt caagattcta tataggtctt gatgatgacc ttatgagatt gtttggtagt
    23641 gatagaatat ctggtattgt agataaaata ggtcttgaag aagatatgcc gatagaacat
    23701 agaatattat ctaagtctat tgaaggagca caaaagaaag tcgaaggtaa aaactttgga
    23761 ataagaaagc atgtacttca atatgatgat gttatgaata aacaaagaga aataatatat
    23821 gcagagagaa aacgtgtatt agaaggtgaa gatttacaag aacaaataca atcaatgact
    23881 cattctataa tagaagaagc agttactctt tatacacaag ataaaggatt tgatgaagaa
    23941 ggatttaaag aacatatgta taatctgttc ttgccaaaag gtagcataga aataccagaa
    24001 atagaaaaac ttaatccagt tgaaataaca gaaaaagttt atgaaatagc tatgaagata
    24061 tatacttcaa aggaagaaca agttggctat gagagaatga gagaagttga gagagtaatc
    24121 ttacttcaag ctgttgataa ccattggata gaccatatag atgctatgga ccaattacgc
    24181 caaggtattg gtcttcgtgc tgtaggtcag caagacccag ttattgctta taaaatggaa
    24241 ggttttgata tgtttgatga aatgaataaa catatcaaag aagatactgt aagatattta
    24301 tttaatataa caatagaaac tccagtggaa agaaaagcag ttgtagatgt tgaaaatcta
    24361 tcttctccat cagatggaac acttccaaca agtaaaactg ttaaaaaaga tgaaaaggtt
    24421 ggaagaaatg acttatgccc ttgtggaagt ggtaaaaaat ataaaaactg ttgtggaaga
    24481 taatctcgga ggattaaatg ttaaagttac aagagtatag acatagtatg gagcagatgg
    24541 cttcaaattt agaagaattg agggtttctc tttgacatag cttcattgat gaaaaatata
    24601 caaattaatg aagaaaagat gaataaacaa gacttttgga atgataatga agtcgctcaa
    24661 agagtacttc aagaaaataa gtctttaaaa gagacattag aagaatatga aagcttaaaa
    24721 agcttactag aagatataga agtattaatt gaaataggtt tagaagaaga tgatgattct
    24781 gtagaaagag atatagaaaa gtccatagaa tcaatggaag aaaaattatc tgaaatgaaa
    24841 ataaagactc ttctaaatgg agagtatgat aaaaataatg ctatattatc tataaatgcg
    24901 ggtactggtg gcttagatgc tcaagattgg gctcaaatgc ttttgagaat gtatataaga
    24961 tggtcagaaa gtaagggtta taaagttaag ctcttagata taatatcaga ccctgaagcg
    25021 gggataaaaa cagctacaat tcttgtagaa ggaacaaatg cttatgggta tttaaagagt
    25081 gaaaaaggag ttcatagatt agtgagaata tctccatttg acccatcagg aaaaagacat
    25141 acttcatttg catctataga tgtaacacca gagttagatg aaaatataga agtagaaatt
    25201 aatccatcag atttaaagat agacacatat agagcttctg gagctggagg gcaacatgta
    25261 aatacaactg attcagcagt tagaataaca catatcccta ctggtgtagt agttcagtgc
    25321 caaaatgaaa ggtctcagca tctaaataag gacagagcta tgagactttt aatggcaaaa
    25381 ttgatagaat taaaagagtt agaacaaaag gaaaaaatag aagatataca aggcaaatac
    25441 tcacaaataa cttggggtag tcaaattagg tcatatgttt ttcaaccata taaattggtt
    25501 aaagaccata gaacaaatgc tgagtttgga aatgtagata gtgtaatgaa tgggaatata
    25561 gacttgttta ttaatgaata cttaaaaatg aataaaatag tttaataaat atgcactgta
    25621 attaagatat atgtataaga aggttagtgc ttaatatgca cttacagcac ttaggctgag
    25681 gacgataacc ctcagccttc gttctgtttt gttatactta tgaaaaacta acattaggag
    25741 tgaataaatt ggatataaat caaattttaa aaaaagagtt taatcttaga gatgaacaaa
    25801 taaataatac attaaaactt attgatgaag gaaatacaat accatttata gctagatata
    25861 gaaaagaaat gactggcgaa atgagtgatg ttacactaag agaattttat gaaaagttaa
    25921 tgtatttgag aaatcttcaa agtagaaaag atgatgtagt tagactaata gatgaacaag
    25981 gtaaattaac agatgaaata acacaaaata tagaaaaagc aaaaacacta caagaagtag
    26041 aagatatata tgctccatat aaacaaaaga aaagaactag agcaacaata gcaaaagaaa
    26101 aaggattaga aaaattagca ttgtcaatac tagagaataa tttagataat atagaaatag
    26161 aggcaaagaa ttatcttgat gaagagaaag aagttctttc tattgaagat gctctaaaag
    26221 gtgctagaga tataattgca gaactagtct cagatgatgc taagattaga aagtatataa
    26281 gagaattagc tttaagagaa ggtatgatag ttagtaaaag tgccactgat gagaaatcgg
    26341 tttatgacat gtattatgat tatagtgaag cagtaaaaag tatgcctcca catagagttt
    26401 tggcaataaa cagaggagaa aaagaaaact tcctaaaggt taagttagaa ataaataatg
    26461 ataaagtttt aaattacata ataaacgaat atgtaaatga taaaaatttc aaaaataaag
    26521 aagaaatcgt aagttcaata gaagattctt ataaaagatt aattttccca tcaatagaaa
    26581 gagaaataag aaatcattta acagaaatag ctcaagaaag agctataagt gtatttggaa
    26641 agaatgttaa aagtttattg cttcaaccac cagttaaaga caaagtagtt atgggatttg
    26701 accctgcatt tagaactgga tgtaaaatag ctgtagtaga taaaaatggt aaactactag
    26761 attatacaac agtatatcca acagaccctc aaaatgatgt agagggagca aagaaagttt
    26821 taaaaggatt gattgaaaaa tacgatatag atataatttc aattggaaat ggtactgcat
    26881 ctagagaatc agaaactttt gtatcagaaa tgataaaaga aatagataac gaagtgcagt
    26941 atgtgatagt tagtgaagca ggagcatctg tttattcagc ctctgaactt gcaaatgagg
    27001 aacatccaga tataaatgta tcaataagag gagctatatc tatagctaga agattacaag
    27061 acccattagc agagcttgta aaaatagacc ctaaaagtat tggcgttggt caatatcagc
    27121 atgatttaaa caaaaagaga ttagaagaag tactagatgg agttgttgaa gattctgtaa
    27181 atagtgttgg agtagattta aatactgcat catactccct actagaacat gttgcaggaa
    27241 taagtaaaac tatagcaaaa aatataatag catatagaga agaaaatgga gattttacgt
    27301 caagagcaca attgaaaaaa gtaaagagac taggaccaca agcatttact caatgtgctg
    27361 gatttatgag aatcttagag ggtaaaaatc cactagataa tacaggtgtg catcctgaaa
    27421 gttatgatat atgtaaaaaa atgattgaga taattggata ttctttagat gatgtaaaga
    27481 ataagaatat atgtgaaata gatgaaaaaa taaaagaaat tggcttgaga gaattaagtg
    27541 aaaaactgga agtagggcaa gttacgttaa aagatatcat aactgaaatc aaaaaaccag
    27601 gaagagaccc aagagaagaa ggtataaaac ctatacttag aactgatgtc ttaaaaattg
    27661 aagatataca agagggtatg actttaaaag gtacaataag aaatgttgta gattttggtg
    27721 catttgtaga tattggaata aaaaatgacg gattagttca taaatcagaa atgagtaata
    27781 gttttgtgaa agaccctatg agtattgtta cagtaggtga tatagtagat gtaaaagtca
    27841 ttggaattga cttaaacaaa aaaagagttg ccttatcaat gaaaaaatag ataagtttat
    27901 gtatggttat agtacttaaa ttctatgttt gtaaatgagg ttactcgagt gtataaatgt
    27961 taaaaatttg taaaagtata cagtaagaaa atatattaaa ataagaacga tagtcttgaa
    28021 aatcaggagg aaaatgaatg atttttataa aaaatggtaa aataaatacc ataacaaatg
    28081 ggataattca tggagatata cttatagatg aaggaaaaat aatagaaatt ggagaagatt
    28141 tgatagctcc tttagatgta gaggtaatag atgctagtaa taaacttgtg tttcctggat
    28201 ttatagatgc tcatactcat ttaggtttgt gggaagatgg tatagggttt gaaggagcag
    28261 atggaaatga agagactgac ccaataacac cacaattaaa tcccatagat ggaattaatc
    28321 caatggatag aacttttaaa gaagcttttg aaggtggaat aacttctgtt tgtacaaccc
    28381 ctggaagtgc aaatgttatg ggtggtcaat gtatagctat aaagacatgt ggaaaaagaa
    28441 ttgataaaat ggtaataaaa aatccagttg catctaaaat cgcttttgga gaaaatccaa
    28501 agagctgtta tggtcaggat gataaatctc ctcaaactag aatggctata gctgctttac
    28561 ttagagaaaa cctaaaaaaa gcagaagaat atttagagga tattgatatg tatgagagtc
    28621 atgatgatga agactgtgaa aaacctgaat atgatataaa aatggaaagt ttaataccag
    28681 ttttaagaag agaaattcct tttaaggcac atgctcatag agcagatgat atgtttacag
    28741 caataagaat tgcaaaagaa tttaatttaa agcttacatt agaccattgt acagaaggtc
    28801 atcttattgt agatgaatta gtggaagaag ggtttcctgt aatagtaggg ccatctttgt
    28861 cagaaaggtc taaatttgag cttagaaatt tgacatttaa tacagcagga atactttcaa
    28921 atgcaggtct tgatgtatgt ataatgacag accatccagt aataccagtt caatatcttc
    28981 caatatgtgc aggtattgca gtcaaacatg gtatgaaaga agaaaaagca atagaatcaa
    29041 ttacgataaa tccagctaag actttaggaa tagaagatag agtaggctct atagaagttg
    29101 gtaaagatgc agacctagta atttgggata attctccact agagattcaa agtaatgtac
    29161 tttacactat aataaatggc aaagtagtgt atgagaaaaa ataacttgac aattattaaa
    29221 aaattaacta atataagagt gtaaggaaaa ttaaaaaatc aaagaagatc ttcggggcag
    29281 ggcgaaattc cctaccggcg gtatagcccg cgaactactt aagtggttga tttggtgaga
    29341 ttccaaagcc gacagtaaag tctggatgag agaagatatt tatggaagat aaataagttt
    29401 attttagttt gtttaaacta tatccataaa aactcgaaga tagggtcttc gagttttttg
    29461 tttttcctaa aaaatataaa catattgatt agggggaaat aattatgcaa aacacagcca
    29521 aaagaggcaa tatgatttca acaagaactt tagtagtaat gtcaatttta tctgcaatat
    29581 cttatttatt aatgtttatt caagcaccaa taccaggtat atttccagat ttcttaaaaa
    29641 ttgacttatc agatattcca gcaatattcg gaggaatgtc tctaggacca tttgttggat
    29701 ttggaatagt tgtagtaaaa aatgtgttac aagcaataac agcaacaaca actggaggaa
    29761 taggagaatt tgcaaatata ttaattggtg gttcttatgt aatgatactt tgttattcat
    29821 ataagagaag tggagattta aaaggtgtat tgattggttt tgtattagga acaatatcta
    29881 tgactataat tggttcatta gtaaattatt ttgtaatgtt gccactttat ggtcaactta
    29941 tgggactaga tgctataata ggtttaggtt cagctataaa tcctcaagtt catgatttat
    30001 tcacttttgt aatttggatg atagctccat ttaatgtgct gaaggctgtt atactatctt
    30061 tagtaacatt gccactttat aaaaaaatgg gaaatgtaat aaagaaataa ttagacaaga
    30121 aaatataaaa ttaaatgtat tgaatagcca taatttattt ataacttcag tcctatattg
    30181 tgattgatat attaaatata ttatggcttt attaatttat caaaaaatgt atataaaata
    30241 agaaatattt agacaaattt aaattttaaa ataaaggaag aattaaaacg attaactatt
    30301 aaaatatgaa aaaggtatct gcaatataca gagcgaattt ataataaata aaaaataaag
    30361 ttattattaa aaaaatataa agattagtaa tcaaattttt aataataact aatttaataa
    30421 tgatgggagt gtatattcat gaacttatct aaaaagataa aaaaattatt tttagatgat
    30481 aaagggtatt attttaatag taattggaaa gatattcata ttggtattta taatacaaaa
    30541 ttaggagatt ctttaaagta tatcactaat gaatatattg aaaatctgga aagggtaaaa
    30601 tatgactatc gtgaattaaa aaatatagaa aatcaaactg atggtatgtg tattttagca
    30661 ataaggcaga attacaaggc attagagtat gtaaaaaatc aaaccgaaga attatgttta
    30721 gaagcaataa agtataatta taaagcactt gaatatgtaa aagagcaaac agaatatata
    30781 tgtcttgagg ctataaaaaa ggattgtaat gcacttaagt atgtacgaaa taaaacagaa
    30841 aggcttatta taaaagtaat acgtcattct tccaatatag atgttgtaag tatactaaag
    30901 gctttagaga ctcaaacaag aagaatatgt ttagaagcaa ttaaaaaaga tggcaggtgt
    30961 cttgcatacg ttagagaaca gagtgaagaa ttatgtatag aggccattaa acaaaattat
    31021 aaagcattaa aatatgtaga aaatcaaacg gaaaaaatgt gtatagaatc cgtaagacaa
    31081 aatggtatgg cattacaata tgtaaataaa caaactgata aaatatgtat agaagctgtc
    31141 aaacaagatg gaagaagtct acaatttgtc aataataaga cagaagaaat atgtataaat
    31201 gctataagat atttaaataa aaaatataat attaaagatg tactaagtta catagataag
    31261 tatacagaag atatatgtat agagattgta agacaaaatg gaaaaatgct tatgtatata
    31321 aaaaatcaaa cagaaaaaat gtgtattgaa gcagtaaaag agaactataa gtctcttaag
    31381 tatgtaaaag agcaatctga gagaatatgt aaagaagcat tgaagcaaaa ccataaagca
    31441 aaagagtatg taaaaattgc tattgatgat tgtatataag gtgtagatac agccatcaat
    31501 agtgaaagat aaaaaaagat aaagacaagt actttataat aatctaggct tatactataa
    31561 ttaattaagc agtgatataa attcacatga cgattatatc aaaatggaga tgaattgatg
    31621 gcaaaaatat atttagaaaa tgaaaataaa actagagaaa taggatataa attaggtaaa
    31681 cttttaaaag aaggcagtgt tatctgttta gtaggagatt taggagctgg taaaactaca
    31741 atgacacaaa gcttggcaga ttcattaggg atagaagatt atataacaag tcctactttt
    31801 actataataa atgaatatga aggaaaaata cctttgtatc attttgatgt ttatagaata
    31861 ggtagtagtg acgaaatgta tgatattggt tatgatgaat atgtaaattc aaatggaatc
    31921 tgtataatag aatgggctaa tctaatagaa gatatacttc caaaagaata tttgaatata
    31981 gaattgagat ataaagatga cggaagagaa atgatattaa ctccaaaagg agagttttat
    32041 aaagagatag ttgaggagtt gattaaataa tgaaaatact aggtatggat acgtcttcta
    32101 tggcagcaag tgtagcagtt gttgaagatg ataacttaat atgtgagttt acagtaaaca
    32161 acaaaaaaac tcattcacaa aagcttatgc caatgataga aaatatgttg agtatgagtg
    32221 atttaagtat aaaagatatg gatttattag ctgtatgtat aggtccaggc tcgtttactg
    32281 gacttagaat aggtatggcc acagtaaaag ctatggctca tgtaaataat ataccaataa
    32341 tagcagtaaa ttctttggaa tctctagcaa ataacataaa tttctgtgat agaaagatat
    32401 gttgtatatt agatgcgcag aaaaatcaag tttattcagc taaatacaag tttgaaaatg
    32461 gagagatgat agaattagat ggtgtagatg ttgtagagtt tgatgcttta gtagatgaaa
    32521 ttgtatcaac taatgaagaa tttataatag ttggagaagc tgtatacaaa tataaagata
    32581 agttagagaa tataaaaaat ataaaaatac cttcaccagc taataatgta tctaacgcag
    32641 gaagcttatg ctctttagca ttaaataaat ataataaaaa tatagatgta catacttgtt
    32701 atacgataaa tcctatgtat atcagaaaat ctcaagctga agtacaatat gatgaaaaaa
    32761 tgaagaggct aaataatgga agataataca aaactaatag tagatgatat aaaaatagaa
    32821 gaaatgacta cagaagatat agatgaagtt tttgaagtag aaaaaaattg ttttgaagat
    32881 tattggtcaa aagagtcttt tagaaaagag ttgtctaatg aagtagcaag gtatatagta
    32941 gctaagttaa atggaaaaat tgtcggatat gtgggaattt ggcttatact tgatgaaggg
    33001 catataaata atgtggctgt tcatagtgac tatagaggga aaaaaatagg ggacaagttg
    33061 ataaaaggca tagttgattt atgtaaagat aataatattg catctatgac attagaagtt
    33121 agagcatcaa ataaaatagc acaaaattta tatagaaaat atggatttaa aatgggtgga
    33181 ataagaaaag aatactacag tgataataaa gaagatgcaa ttataatgtg gaaccaatta
    33241 aaagaggtgt agagtttatg agtgatataa taacattagc tatagagagt agttgtgacg
    33301 aaacagctgc atcagtttta aaaaatggta gagaagtact ttcaaacata atctctactc
    33361 aaatagagac acataaaaaa tttggtggtg tagttccaga agtggcttca agaaaacatg
    33421 tggaaaatat tgatatagtt gttcaagaag ctttagacaa agcaaatata ggttttaatg
    33481 atatagacca tatcgcagtt acatatggac ctggactagt aggtgcttta ttggttggtc
    33541 tatcttatgc taaagcactt gcatatactt tgaatattcc acttgtagga gtaaatcata
    33601 tagaagggca tctaagtgca aactatatag agcataagga tttgaaacct ccttttataa
    33661 cattaatagt atctggaggt catactcact tggttgaagt aaaagattat ggcaagtatg
    33721 aaattttagg aaaaacaaga gatgatgcat ctggagaagc attcgataaa atttcaagag
    33781 caatgaattt aggttatcca ggaggaccta ttattgataa tctagccaag aagggaaata
    33841 aacatgctat agagtttcca agagcctatt tagaagaaga tagttatgat tttagtttta
    33901 gtggattaaa atcttctgta ttgaattatc taaatgggaa aagaatgaag aatgaagaaa
    33961 tagtagttga agatgtagca gcatcttttc aagaggctgt ggtagaggtt ttatctacta
    34021 aggcactaaa agcagtaaaa gaaaaaggat acaatatcat aactctttct ggtggagttg
    34081 cttctaattc ggggcttaga gctaaaataa cagagcttgc taaagacagt ggtattactg
    34141 ttaagtatcc tcctctaatt ttatgcacag ataatgcagc tatgataggg tgtgcaggat
    34201 attataattt tataaacggg aaaacgcatg atatgagttt aaatgcagtt ccaaatttaa
    34261 agataaatca gtagagttag ataaatttgt aaatataaaa gtattgtttc aaaaaagtaa
    34321 gcagaagtga aattaaatat aataaaaatc aatatagtat atattaaaac ttgaagtaaa
    34381 actatttata atctttatat tccaatgaat tgcaacacat tttaggatat acaggttgtc
    34441 tttggcttag atttgcttca agtttaattt tttctataga aagattattt taaaaagtgg
    34501 gtaatatacc cttttttttc attcttaaaa agttttatac taattataga aagattaagg
    34561 aggggaagaa atgagtcaaa gtaaagaaga caaaataaga agtattttgg aagcaaaaaa
    34621 tatcaaatca aattttcaaa ataaagaaaa tttaagtgaa tttaatgaaa aaaaagcaag
    34681 taaaagagca gaagacttat tagatgtata ttataataca ttatctactg cagatatgga
    34741 atttccatat tggtataata gagaatatag aaaatcagat ggtgatatac cagtagttag
    34801 aagagctaaa gctcttaaat ctgctttttc acatatgaca ccaaatataa tacctggtga
    34861 gaaaatagta atgcaaaaga cacgccatta tagaggttct tttccaatgc catgggtaag
    34921 tgaaagtttc tttgttgctc aaggagaaca aatgagagaa gaggcaaaga aattagccag
    34981 taacacagct gatgaactta caaaatttgg gtctggcgga ggaaatgtta ctgaaagttt
    35041 tggaaatgtc gtttcaatag ctggtaaatt cggaatgaga aaagaagaag tacctgtact
    35101 tgtaaaaatg gcaaaagaat gggttggaaa gtctgttgaa gatttaggtt ttcactatga
    35161 aaaaatgatg ccagattatg atttaaaaga aaacctaatg agtacactta tatgtatgtt
    35221 tgattcagga tatacacttc ctcaaggtag agaagttata aattattttt atcctttaaa
    35281 ttatggatta gatggaatta tagaaatggc aaaagaatgt aaaaaggcag ttgcaggaaa
    35341 tgcatctgga gatgggctta ttggtatgga ccgtctatat ttttatgagg ctgttattca
    35401 agttattgaa ggattacaaa cttggatttt aaattatgca aaacatgcaa aatatttaga
    35461 aagtatagag acagatttag aagctaaaaa agaatactca gatttagtgg agatattaga
    35521 acatattgca cataaacaac ctcgtacatt tagggaagct cttcagttga cttatacaat
    35581 tcatatagca tcagtaaatg aggatgctat atctggtatg tctataggcc gttttggtca
    35641 aattttatat ccttggtatg aacaagatat agaaaaagga ttaattacaa aagaagaggt
    35701 tatcgaatta ttagagcttt atagaataaa aatcacttgt attgactgtt ttgcttcagc
    35761 gggcgtaaat ggaggagtac tatcaggaaa tacatttaat actttatcta taggtggatt
    35821 aaaagaagat ggttctacag gagctaatga actagaggag ttattattag aagcaagtat
    35881 gagatgtaga actcctcaac ctagtttaac tatgttatat gatgaaaaac ttccagaaga
    35941 tttcttaatg aaagctgctg aatgtacaaa gcttggttct ggttatccag cctgggtaaa
    36001 caactcaaat ggaacaacat ttatgatgaa acaatttgct gatgaaggta tgactgttga
    36061 agaagcgaga gcatttgcat taggaggatg tttggaaacg tctccagggt gctggaaaca
    36121 gttaacttta aacgggaaga catactctat tgcaggtgga gcaggtcaat ctgctggctc
    36181 tggagttcac tttatagcta atcccaaaat tttagaactt gttcttatga atggtaaaga
    36241 ccatcgtatg aatatacaag tatttgagcc tcataataag ccattagata cttatgaaga
    36301 agtcatagaa gtatttaaag attattataa acaagcaata aatgttttag aaagagcaaa
    36361 taacattgag ttagatatat ggagaaaatt tgatacttct ataataaatt cactattaaa
    36421 gccagactgt ttagacaaag gtcaacatat aggaaatatg ggatatcgtt ataatgcaac
    36481 attaaacgta gaaacttgtg gtactgttac tatggtcaat tcatttgcag cacttaagaa
    36541 acttgtatat gatgacaaag catttacaat agaggaaatg aaggatgcca tattaaataa
    36601 ttttggattt aaagatgcat tagaagtagg aaattattct atggcagacc aagtaaaagt
    36661 agataagact ggtaaatatg atgctattta taaggcctgt cttgatgcac ctaaatatgg
    36721 aaataatgat ttgtatgcag ataatattct taaaaactat gaggtatggt tatcaaaagt
    36781 atgtgaagaa gcacaatctt tatatgctaa gaagatgtac ccttgccaaa tatctgtttc
    36841 tacacatgga ccacagggag ctgctacctt ggctactgca gatggtagac taagtggaac
    36901 aacatattca gatggttcag tctctgcata tgcaggaaca gataaaaatg gggtatatgc
    36961 attatttgaa tctgcaacta tttgggacca agcagtagtt caaaattctc agatgaattt
    37021 aaaacttcat ccaacaacta taaaagggca acaaggaact aaaaaattat tagatttaac
    37081 aagaagttat ttaagaaaag gtgggttcca tattcaatat aatgttgtag attcagaaac
    37141 attaaaagat gcacaaaaaa atcctgacaa ttatcgtcaa ttaatggtac gtgttgctgg
    37201 gtttactcaa tattggtgtg aattaggtaa accaatacaa gatgaagtaa ttgctagaac
    37261 agagtatgaa ggggtgtaaa atatgagaaa gcatagtgat tgtatgaatt tttgtgcagt
    37321 agatgcaacc aaaggaattt gtagattatc aaaacaaatg attaatttag atgatgcagc
    37381 atgtccagag ataaaagtaa tgccaaaatg taaaaattgt aaaaattttg ttgaagctaa
    37441 tgatgaaggt ataggcaaat gtgttggcct agagaaagaa gactgggtat attcaacatt
    37501 gaatgcaatt acttgtgaag gacatgtgtt taatgagtag tcaaaagcaa ttagaaggca
    37561 tgattttcga tgtacaaagc ttttcagttc atgatggtcc aggttgtaga acaactgtat
    37621 ttttaaatgg atgtccactg agttgtaaat ggtgtgcaaa tccagaaagt tggactgtaa
    37681 gaccacatat gatgtttagt gaattatctt gtcaatatga aaatggatgt actgtatgtc
    37741 atggtaagtg taaaaatggt gcattgagct ttaatcttga taataagcca gttatagatt
    37801 ggaacatctg taaggactgt gaaagttttg aatgcgtcaa ctcatgttat tataatgcgt
    37861 ttaaattatg tgcaaaacct tacactgtag atgaacttgt gcaggtaatt aaacgtgatt
    37921 ctaacaattg gagaagtaat ggaggagtaa catttagtgg aggtgagcca ctacttcagc
    37981 atgaattttt acatgaagta ttattaaagt gtcatgaggt aaatatacac actgccattg
    38041 aaacgagtgc atgtgtatca aatgaagttt ttaataaaat atttaacgat attgattttg
    38101 catttattga tataaagcat atggatagag aaaaacacaa agaacaaaca ggtgtgtata
    38161 atgatttaat attagaaaat atatcaaacc ttgcaaattc tgattggaat ggaagattag
    38221 tacttagagt accagttatc tctgggttta atgatagtga tgaaaatata agtgatatta
    38281 tatcttttat gcacaaaaat aatttggtag aaattaatct attaccattt cacagattag
    38341 gagaatcaaa atggattcaa ttaggcaagg aatatgagta ttctgataag ggtgatgttg
    38401 atgaaggtca tcttggagaa ttacaagata tatttttgga taatggtata gcttgttatg
    38461 ttggtcatga gacagctttc taaaattaaa tacaagtttt aattaaaaaa ggatgttaca
    38521 ctaaaagcta gagttacatc cttttttatg tggtttttat gtagaaataa ttaagtaaag
    38581 ttttatatat tttatatatt gtttatattg ctttatgtcc ataaatattg ctttaaatat
    38641 actttatata ttttttatag tttaaattac agttagagaa tatattacgt ttactttatt
    38701 gaagcagaag ttttgtggta aaatactact atgaaaaaat ttaatagaat atattttaga
    38761 aacaactaaa aataatagtt aggaggaaga catctatatg aacaaatcat ggagcaactt
    38821 gattattaag aataaagaca aaaaagtacg ttcagggtgg attattatag ctgttatggc
    38881 taccttttac atatttcagt attatttaag catgatactt gtggaaataa taagaaaaat
    38941 cctggttgct acaggggaca ttaatttaaa aacaaactat ttttcagaat atgctaattg
    39001 gttaaatgat gttgggttac agattgtatt tcaaattcta acagattcac ttatgattat
    39061 tattcctata attgtatgga gatttattat gaaaaatcct attagtgaaa tgggattaca
    39121 ttcttataga attaagaaaa aagaaggata tgtaggaatg ttattaggaa tatttaattg
    39181 tacagtaatc tttattataa caataacaat tggtggtggt catgttactt catgggtacc
    39241 aaaaatttca cctttaacag tttcttgaat acttgtcttt attttagttg cttttgcaga
    39301 agaaatttta aatcgtggtt tttttatggc agttttacga agatgtaaaa atatttattt
    39361 tataatgatt gttccatctg ttatttttgg gttgattcat atatggaatc ctgatgttac
    39421 ttttttgtct gtaattaata ttataattat tgggattctt ttttcatata tgtttataaa
    39481 gtcgtcgaat atatggatgt gtataggtta tcattttaca tggaatgtat ttcaggggat
    39541 tatatatggt atgcctgtaa gtggacttca ggttccaggg attataacta cacaaatcac
    39601 tcatggtaat ctattaaatg gtggtatgtt tggtattgaa ggtggaattt tgactacttt
    39661 tgttaatcta cttagtttta tatttgtatg gtattactat agagattcta agtatgattt
    39721 tgttagtgat aaagtaaatg tgaccaatat caagaattag ttgattataa taaattttaa
    39781 taatatcttc taagcttaaa gtattctgta ggattgttgg aaatttacaa aaatataaaa
    39841 ataacttgga tattctattt actccaagtt atttttatat tcttttgtaa atagaaatgg
    39901 aacataaaaa attaaaacaa ccatagatac tattagtata tcatggtaag tgatagttga
    39961 ttctttagaa tttgtgataa gaaaagcact attatttaaa atatgaatta tagcacaaaa
    40021 ccagatgttc ttagttttta tataaagata tcctaaaaat attgaaattc caactatatg
    40081 tatcgaacgt aatattaatc ctaatattgg tgtttcaggt gtatataatg taaatattag
    40141 tggtaagtgc cacaaactcc aacaaatacc taatattata actcctagtt ttttaccaaa
    40201 tttattaaaa aaaatattct gtaaaaaacc tctccaggca tattcttcac taaaaaaaat
    40261 ataaatagta gttaatgatg ttattggagt aaatataaat tttatgatac cactataatt
    40321 aggttgagac ccttgtagta ttaatataaa tgatgttgga acaattacag aaatcataaa
    40381 gtaaataatt aacaaagaac ctagtttaat attttttata ggatataaat tttttttatt
    40441 tgatgaatat attataattg ataaactact tataaaagtt aatattaggt ttataattat
    40501 aaattcatta ttatttatta gatttaataa cttaagaaca attaataacg aataagtaag
    40561 aaaaaatagt atgattagtg aata
//
LOCUS       DAEPHU010000033        39527 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 01A10CD0081
            SAMN05941466-rid12468953.denovo.033, whole genome shotgun sequence.
ACCESSION   DAEPHU010000033 DAEPHU010000000
VERSION     DAEPHU010000033.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941466
            Sequence Read Archive: SRR6291087
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 39527)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 39527)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068158.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 22:43:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,892
            CDSs (total)                      :: 3,805
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 87
            rRNAs                             :: 8, 1, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 55
            CDSs (without protein)            :: 55
            Pseudo Genes (ambiguous residues) :: 0 of 55
            Pseudo Genes (frameshifted)       :: 21 of 55
            Pseudo Genes (incomplete)         :: 28 of 55
            Pseudo Genes (internal stop)      :: 16 of 55
            Pseudo Genes (multiple problems)  :: 8 of 55
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..39527
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941466-rid12468953.denovo.033"
                     /strain="01A10CD0081"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            complement(<1..1149)
                     /locus_tag="KR231_001830"
     CDS             complement(<1..1149)
                     /locus_tag="KR231_001830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HBH0004208.1"
                     /translation="MEKIVNDILKEEVYYEKLQNGLDVYFMPKRGFMKKYAILATNYG
                     SNDLEFVPIGEDKKIRVNEGIAHFLEHKMFEQPDGGDAFDKFSKLGVNANAFTNFTMT
                     AYLFSATENFYESLEHLIDYVQTPYFTDENVEKEKGIIAQEIKMYNDDPDWNVYFNCL
                     KAMYVNYPARIDIAGTVDSIYKITKEELYKCYNTFYNPGNMALFVVGDLDVEKVIDVT
                     KKSNNYKVDKLSKSIERFYPEEPEGVKEKEVIEKFPISMPMFNIGFKDSNVGLKGKEL
                     LRKEIVTDILVGMLFKKGSKLYEDLYMQGLINENFGAGFSSQVDYAFSIIAGDSKEPK
                     KVKEIILDYIEKSKKEGLSKEEFERTKKKKIGSFIKCFDSINFIGNSFI"
     gene            complement(1164..2429)
                     /locus_tag="KR231_001831"
     CDS             complement(1164..2429)
                     /locus_tag="KR231_001831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HBH0004209.1"
                     /translation="MVNTKKIINLGNNINLTLIKTEKFKSNLISLYVQRLLDEKETTK
                     NALIPSIIASGSSKYPSARAISNKLDDLYGSSMGADAVKRGERQVLSFKVINISEKYL
                     DESIFEEVVEFFNEVINNTLVVDGGFKEEYLNIEKENLREKIQSIINDKKEYAQDKCI
                     EAMCKGERYSVSEFGYEDEIDSITSRELYEHYKNILKTSPIDIVVEGNFDEDKVVDII
                     SKNLKFEREEIINIPRADFIKNVDEVKVIDEQMEITQGKLVMGYRANVDYADIDKYYA
                     LVVGSNVLGGGPHSKLFVNVREKESLCYYIFSSIEKYKSIMFISSGIETKDYDKAVEL
                     IKKQVESVKAGDISDEELENSKLALVNSMKSITDNIGGMSDFVFSQSMAKTNSEVQDI
                     ISSIEKVTKKDIVEAIKNIELDTVYFLRN"
     gene            2745..3842
                     /gene="ychF"
                     /locus_tag="KR231_001832"
     CDS             2745..3842
                     /gene="ychF"
                     /locus_tag="KR231_001832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-regulated ATPase YchF"
                     /protein_id="HBH0004210.1"
                     /translation="MKLGIVGLPNVGKSTLFNAITQAGAESANYPFCTIDPNVGVVSV
                     PDERLNKLQELYNSEKIVPTAIEFCDIAGLVRGASKGEGLGNKFLSHIREVDAIVHVV
                     RCFEDENVVHVDGSVDPLRDIETINLELIFSDIEILERRINKTQKAAKADKTLGSELD
                     LLKSIMSTLEESKCVRTMEFTEDEQTFVNSLDLLTSKPVIYASNVSEDDLADNGENNK
                     YVQQVKAFAETEDAEVVVVCAQIEAEISELDSAEEKKEFLETLGLEQSGLDKLIKSSY
                     ALLGLISFLTAGPKEVRAWTIKVGSKAPQAGGKIHSDIERGFIRAETIAFNDLVEHGT
                     MAAAKEKGLVKLEGKEYIVKDGDVILFRFNV"
     gene            complement(4321..6600)
                     /locus_tag="KR231_001833"
     CDS             complement(4321..6600)
                     /locus_tag="KR231_001833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EAL domain-containing protein"
                     /protein_id="HBH0004211.1"
                     /translation="MLSDAKNNRYGLSIIAVISILVITISCLIYGSRLNKTLGEETNQ
                     YLSEIANQSVNVLKKQINGDIKLLESISIFIEGEESFEVDNILSILKRQAINSSFKRM
                     GVILPNGTAYTTDGYIEDFSKRDYFLKSMQGEVVITGKLKDVIEDDKNTNSNINVYSV
                     PIYKDNEVKGVIFATHSTKLYEKILSVPTFNGKGYSYITRSNGDIVLNPSSKNANSTK
                     ENLFSYIGRSDSISKSSINNMKSNIKNFKSGSLSYSMFGKGYYLSYAPIGINDWYLFS
                     EVPKTAISEKSYAIIKLTLSACVVLIIIFTALTIYILFIHKKSKEKLEEFAFKDNVTG
                     IGNSNKFNLEGGKFLSSHEKKNLVLIYFDIDKFKLVNDRFGYEEGDRVLKEIAEIIKN
                     IFKEQSVFSRISNDNFAIIFEKKNNRESIIEICELIRKKLSMIKTSLGVELNLIPSIG
                     VYFVEEGETNISTCLDKAMIAKTTVKRKYLKVYEIYAENLKETLIEERDIEQEMHDAL
                     KNEQFKVYLQPKVDLSTTKIVGAEALVRWQHPKKGLISPGVFIPIFEKNGFITELDMF
                     VFTQVCKNFKRWENENFPTFPISINLSRVHLENPGFISELERITKEYEIEPNLIEIEL
                     TESAIFDNTKILFKIMQTLKSVGFKISMDDFGSGYSSLNMLKDMPIDVLKLDRQFFIT
                     VGNAKKSQIVVSSIVQMAKQLDIKVVSEGVETVEQAEFLRFIGCDMAQGFLFARPMPI
                     EEYEKLILDRYSLNRKETN"
     gene            complement(6871..8325)
                     /locus_tag="KR231_001834"
     CDS             complement(6871..8325)
                     /locus_tag="KR231_001834"
                     /EC_number="6.3.2.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,
                     6-diaminopimelate ligase"
                     /protein_id="HBH0004212.1"
                     /translation="MKLNDIIQGLDIINIKGELNIDINNVQYDSRKVTKGTLFICIKG
                     FVSDGHKYIKDAIEKGASAFLVEEDVEIKGCTFIKVKDTRKDMAKVADNFYNHPSQKF
                     NVIGVTGTNGKTSITTILNEILTLNKNKVGLIGTIKIFDGEKDIVSNSTTPESIDLQY
                     HFNNMLDNGCDYCAMEVSSHSLALNRVDETDFKLGIFTNLTPDHLDFHKDLEDYRKAK
                     EKLFFKTTMANIINIDDEGGKKIYENIKGINVPCYTYGVDTKADFMARDIKSDSDGVS
                     YRLITPSYEEVIFIPVPGMFTVYNTLAVIAACYVLGIPKPIYKEGLRLSNGVSGRFET
                     VPNDKGISVIVDYAHTPDALENVLKTTQQFAEGKIISVFGCGGDRDTEKRPLMGAIGQ
                     KYSDLCIITSDNPRTEEPEAIIKDILEGIDKKKENYHVVVDREQAIAEAISMAKKDDV
                     VIITGKGHETYQIIGKVKHHFDDKEVANECLSKM"
     gene            8489..9358
                     /locus_tag="KR231_001835"
     CDS             8489..9358
                     /locus_tag="KR231_001835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBH0004213.1"
                     /translation="MDNKIGYLNDNFKIFNIRDKKDIQFEYHNHDFNKIIIFINGNVT
                     YFVDGIPYKLKPWDILFISNNEIHKPVIDSNVFYERIAIWISPEFMKKNSDASSDLEK
                     CFKIATENKCNRLRLNIHDIESIKSFIEQINISESNTEFGNEILRNALFIQLMIFLNR
                     IFLKNENMESTEDVFYDETIKKVLNYINSNIDDKLSIDSISSEFFISKYYLMRKFKSH
                     TGTSIHNYIVQKRLILAKSLITNGHLMSEVCNKCGFNDYSSFVRAFKKNYGVSPKNYI
                     NNKNPLDITLLDE"
     gene            complement(9571..11643)
                     /locus_tag="KR231_001836"
     CDS             complement(9571..11643)
                     /locus_tag="KR231_001836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HBH0004214.1"
                     /translation="MKKVFGVLQKVGKSLMLPVALLPAAGILLGVSNALAGDALLAHF
                     PALANPTFQLIISIMESSGQIIFNNLPLIFAVGVAVGLTEGEGVAALAAIVGFLILNT
                     SMGVMAGVTEDMVDNSMYANIVGIPTIQTGVFGGIIIGIVAAYLYKKFYKIELPQYLG
                     FFAGKRFVPIVTSLVAIAIGIILSFIWPPIQEGLLSFSKNVIEANQTLAAFMEGSLER
                     LLIPFGLHHVFHNPFWYQFGEYVNKAGELVMGDQKIFFAQLKDGVNFTAGTFMTGAFP
                     FMMFGLPAAALAMVHEAKPEKKKFVAGIMASAALTSFLTGITEPIEFAFLFVAPVLFA
                     IHCLFSGLSYAIMQLLGVKIGFTFSGGLIDFLLFGVLPNRTPWYLAILVGIGFAVLYY
                     SVFRFMIRKFNLKTPGREDESETNAEVIEMSKNELASEILIALGNKDNLKSLDACITR
                     LRLVVNDINKVDKEKLKSLGAAGVMVIGNNVQAIFGPKSDSIKSDIKDIIEGKTKVES
                     TVTKNVDKNKVKKNMEVANMENALVEKIDSLTNGEILDIEEVPDSVFSSKLMGDGFAI
                     KSSDGLIYSPVDGTIGVIFPTKHAIIIKSQKSGVEILIHLGIETVNLEGNGFEVFVNV
                     GDEVKAGEKLVKMDLEYIEKNGLSTISPVVFTNLEQNQKLSIKKGVSTAKEENRVSIL
                     RDDIEKIG"
     gene            complement(12179..12574)
                     /locus_tag="KR231_001837"
     CDS             complement(12179..12574)
                     /locus_tag="KR231_001837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009265990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0004215.1"
                     /translation="MLKEQDIKQYLNEKGSAFKENTSIIGVIFPSKFTYALGPVATAL
                     SMQYYAINFGDSGIAVIGLNNVTGKLENEAFLFVPKEEVTSVKFNKKLMSYELEISTS
                     QGTLAFKVNKTMVGASWHKENLATILKSL"
     gene            complement(12674..13417)
                     /locus_tag="KR231_001838"
     CDS             complement(12674..13417)
                     /locus_tag="KR231_001838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009587569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0004216.1"
                     /translation="MRYKKILLGVIASVLCLGLLNSCSGYSHDFNSSEEAQKYILSKL
                     KDKYNEEFIITEVKKYKEEKIGLNWIMAEVSSKENSSQTATVYTRNTGLFEDSYHVYY
                     YFDEIKELATPLFQDKPFIRDYQIEVQGHTATTEWNGKESVEEYLKKREYEIETSIYL
                     NEGKTDEEYAEEISYIMQEIVESDLVFNISVYTNDNNLIFYSLPEQHSQPEVEVILEK
                     MEDVKRQQETKKDFKEWKKQNLNNETNSD"
     gene            complement(13463..13792)
                     /locus_tag="KR231_001839"
     CDS             complement(13463..13792)
                     /locus_tag="KR231_001839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004221612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4274 domain-containing protein"
                     /protein_id="HBH0004217.1"
                     /translation="MIYNDLRSKLNEYNWDDGFEIPKQILADSSCDLALALEIFYLSD
                     GYAFLDDSTKTADLKEWGRFITVLYDDILNNKFPKTSTAFEIPLSQVQKYKLQKKDIS
                     KIFLTDL"
     gene            complement(13845..14621)
                     /locus_tag="KR231_001840"
     CDS             complement(13845..14621)
                     /locus_tag="KR231_001840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009587605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0004218.1"
                     /translation="MMNGQMFQIASIVATSKKALQLSEPIRFSQLEYENKIEFVFLPQ
                     KKFLRTEKYTASNVSLWFEQIKKNGIQDIKLLCPYSVKDRQFLGFSNTTESSILCFYK
                     SGKVTYFTADWQFDSMQKKWNILYSEHEWTNSPSKKPYFENNINSFRDVLLSIKELAK
                     KIECENFANIFTSAINLLDGCSEYPDEKYGLSLPPIPQQNLQMFEAASISDVFGAMGS
                     WNDSPAYMAHKKGLSEEYETLSSELLKNVRLAILYAINEW"
     gene            complement(14668..14852)
                     /locus_tag="KR231_001841"
                     /pseudo
     CDS             complement(14668..14852)
                     /locus_tag="KR231_001841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322213.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(14899..15570)
                     /locus_tag="KR231_001842"
     CDS             complement(14899..15570)
                     /locus_tag="KR231_001842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008393244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBH0004219.1"
                     /translation="MEHYEKKISFLGENIQTIRKHRGMKQQELADKIGINMQSLSKIE
                     RGVNYPTFDTLEKIMDVLGVTPNELLSGEWKYIDHTEPYIMDIIKREQDFNVSLDYLS
                     ENEFFDNENEYRFYMETILIRYISNYLSNEVVEIEELMEIKQLIQRQKIERMMKVHKE
                     MRGLDRYREQPKEYKYHNPYDDWIFRQLADIDNRKNIPNTSPQVDFNEGDYEDYLKAK
                     WNRGL"
     gene            16037..17128
                     /locus_tag="KR231_001843"
     CDS             16037..17128
                     /locus_tag="KR231_001843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018594174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation factor domain-containing
                     protein"
                     /protein_id="HBH0004220.1"
                     /translation="MTTHKNLSVKIDYISIVFDTATAEDVIMHILGLPTDIFNVYPAS
                     IKYKTYQARWQIGDIYVSGDARKTEDNPQGLGCYLVMTGRGCDDIFRILDSRNYTFGD
                     MFRRCERRYGLDNFHFTRLDIAIDDKNEKPFFTIEQIKKKCEKEEFISNSEGYHFDES
                     KFDDFDTAKTVYIGAGKSGLSYRFYDKDKEVCSKHNKTLEEVGSWKRTEMQLRDDKAH
                     AFAMTFKDRPLELGELAFGLLANNLRFVVPNRNESNKSRWKTCRFWERFLGAVEVLKL
                     QVPKQQNSLEETQQWLTEGGVISAVKSFYFLEEHDALGGLEKVGTMLDKARYSNSLSS
                     KLTAHLQRINRTDLIPYIQYDTKHGKGGI"
     gene            17128..17331
                     /locus_tag="KR231_001844"
     CDS             17128..17331
                     /locus_tag="KR231_001844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006730246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excisionase"
                     /protein_id="HBH0004221.1"
                     /translation="MKNNDIPVWEKYTLTIEEASKYFRIGENKLRRLAEENKDAGWLI
                     MNGNRIQIKRRQFEQVIDKLDAI"
     gene            17410..18603
                     /locus_tag="KR231_001845"
     CDS             17410..18603
                     /locus_tag="KR231_001845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005336078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HBH0004222.1"
                     /translation="MKEKRRDNKGRILHTGESQRTDGKYLYKYVDAFGNTKYVYAWRL
                     TPTDPTPKGKREKPSLRELEQQIRRDIEDGIDSTGKKMTLCQLYAKQNAQRANVKKST
                     MKQREQLMRLLKEDKLGARSIDTIKPSDAKEWALRMKDKGFSYNTINNHKRSLKASFY
                     IAIQDDCVRKNPFDFKLSEVLENDTKEKVALTEEQEQVLLSFIKTDNVYHKHYDDVLI
                     LLKTGLRISELCGLTVADIDFKNEVVIIDHQLLKSKEQGYYIETPKTKSGIRQVPLSR
                     ETIQAFQRVMKKRPKAEPFVIDGRSNFLFVNHKGKPKVAINYNALFIRMVKKYNKHHK
                     DNPLPHITPHTLRHTFCTRLASKNMNPKDLQYIMGHSNISITMNWYAHASIDTAKSEV
                     QRLIA"
     gene            complement(18772..19614)
                     /locus_tag="KR231_001846"
     CDS             complement(18772..19614)
                     /locus_tag="KR231_001846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HBH0004223.1"
                     /translation="MIIQQIYNNNVVLVLDENIKKELILTGCGIGFQKKKGQEIDKSK
                     IERTFVIQDESFLDKISKLASQVDEKFFEVSTEIIAYAEENLNTKLYEYIYVALTDHI
                     AFAIKRYHENITIKNDLLHEIKRIHKKEYEIGKWAVDYINKEFDVKFPVDEAGFIAMH
                     IVNSNYKGSSKESLLITKIVKDILNIIRYYYRVEFKEDDINYDRLLTHLKFFAKRLVK
                     KEKINDTNNEIIDIIKVKYEKDYDCAYKIKTHVEKNYDYYVSQDELLYLTLHIKRVIS
                     VLNL"
     gene            complement(19875..21917)
                     /locus_tag="KR231_001847"
     CDS             complement(19875..21917)
                     /locus_tag="KR231_001847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:proton antiporter"
                     /protein_id="HBH0004224.1"
                     /translation="MSILVTLLGLLVCTTISTVFSKKWSNIPLAIYQIVLGIILSILP
                     FKFSFSFNPEIFVICIIAPLLFSEGQNVSRKELLELRKPILLLAFGLVLITVFAGGIF
                     IHFLIPGMPLSVSFALAAVISPTDLVAVKSITQGLNFPKNIMSILEGESLLNDAAGVV
                     AFKVAVLATVTGVFSIEEAGIQFMITAFGGIIVGSILGYIIIKIRLSLHKWNLEEIPM
                     VIVIQIMTPLFVYFVAEEIGVSGILAVVMAGIAHGIEKEHLQNTTTKLRIISDNTWYV
                     LEYVLNGFVFTLLGFLLPSIYTGLSSKNENMALELTFISTLIVLILFVIRFIWVYLWH
                     NSFIKPKKNPLNNFFVGFLGFKDEEVIKESISKCKYSLIVATCGVHGTFTLATALSIP
                     FYLADKDVFPMRDTVLFISSEVILISLVLATILLPRLLKNNVQESEPLLSDKEAYKLI
                     LKEAILKLSNEKAQEVQPVIHDLNEQLVDSEKGILNTPDNKLISMMIAEADQQGLLAV
                     LKLLEDGKISDRAFKLYRFYITKSRKSVQKSIFKIVKLKISMWIINRKVKKEVKEKIT
                     KIVSENKEIIKEFHHAYALSTKTAISFINKNTDEDNRHEALIAIRFYNRYLNWITRKI
                     QNDDKFEARVEYYRVMAIQSQRDSVQQLVETKQISREVAKELLENILYDEMMMIES"
     gene            complement(22069..23040)
                     /locus_tag="KR231_001848"
     CDS             complement(22069..23040)
                     /locus_tag="KR231_001848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptide ABC transporter ATP-binding protein"
                     /protein_id="HBH0004225.1"
                     /translation="MKKEESLLKVEGLKKYFEVKSGLFDKKIKSVKAVDGISFDLKKG
                     ETLAIVGESGCGKSTAGRTILRLIEKTEGKVEFNGVDIYKLEKEELRKLRPKMQMIFQ
                     DPYSSLNPRLNVEQIISEAVIEHNLVPKNEIKDNILNVVESCGLSKYHLNRKPGEFSG
                     GQRQRIGIARALALNPEFIVCDEPVSALDVSIQSQIINLLMDLQDKYKLSYLFISHDL
                     SVVNHIAHRVCVMYLGSIIEIATKGELYLHSQHPYTKALMSAVPIQDPTIKKNRIILK
                     GDIPSPTNPPSGCKFHTRCPYCKEICKKEIPVLKEISRNHFVACHLV"
     gene            complement(23041..24018)
                     /locus_tag="KR231_001849"
     CDS             complement(23041..24018)
                     /locus_tag="KR231_001849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH0004226.1"
                     /translation="MSKALIEVKDLKVYFHTDKGIVKSVNEVSFNINEGETIGIVGES
                     GCGKSVTAMSLMKLLPTSKIEGGEIIFRGKDILKMNEDELMGIRGNEISMIFQEPMTS
                     LNPAFTVGSQIIEGIMIHQDLSKEEAKKKVIDMIKLVEIPRAEEIYNSYPHELSGGMR
                     QRIMIAMALSCNPKLLIADEPTTALDVTIQAQILDIMKNIKEKLNTSIMMITHDLGVV
                     AEMCDKVLVMYAGKIIEVAEVVELFKNPKHPYTIGLLKSKPALGKNKDKRLYSIPGQV
                     PNPIGMPDSCYFSDRCEKVCDKCRTQIPPLIELNSGHSIACWLYKKEEI"
     gene            24237..25796
                     /locus_tag="KR231_001850"
     CDS             24237..25796
                     /locus_tag="KR231_001850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HBH0004227.1"
                     /translation="MKFKKLASLILVSSLMLTFTACASNDKDKSSGSKSGGTVVIPMA
                     SDPDIINGAFANVKEDSLASNIVYAPLYTYEKGNLVNYLAEKVDFKDSKELTIKLKSN
                     LKWHDGKPITAEDVLFTFNTVLDEKQNSPSRQYLLVGEKPVKVEKIDDLTVKITLPTA
                     SESFLYGISKISPIPKHVFEGESNIAKSEKNNNPVGSGAFKFKEWKKGESIVFEKNAD
                     YFGGEPKADSIALKIIPNEASQEAALNNGEISLMKTSAEGYEKAKSNSNLQTYTYSEE
                     RLNYIVFNQNISNMANKEVRQALSYALNRNEMIESAYGKEGSVPAKSILVPEADFYTE
                     EGVEGYDQDTNKAKDLLDKSGVKIDKLKIGYNTGRFGHKNYALVAQQELKKIGIEAEI
                     VPYESKAFFNILFSNSTECDMYVNGYAWGLEPNPYRGMFETGQYCNQTKYSNAEIDAL
                     WEKGFTELNKEKREEIYKQIQQDISKDAPIYTIDYEQNLMAAQKNLKGIKDAKPSPAI
                     LFEDWSKLYVE"
     gene            25902..26861
                     /locus_tag="KR231_001851"
     CDS             25902..26861
                     /locus_tag="KR231_001851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBH0004228.1"
                     /translation="MLKLILNRVKVLIPMLILISILSFGLLELAPGDPADAYINPLMS
                     SQDIENIRVNMGLDKPVYIRYLNWLKNTLSGNLGISYINHMPVTEQIMEKMGNTFILM
                     GTSLIFSILVAIPLGIFLAVNKNSITSKVSSVFNYIGVSIPSFWIGMILISIFSVKLN
                     IFPSGGMHTIGNDSIGDLVKHLVLPVITLGLYNTAIFTNYVEASVNEQLKKQYVITAR
                     AKGLSEKVILFKHVLKNSLTSLVTILGMSIQKLVTGAFVTEVVFSWPGMGRLMIDSIF
                     SRDYTVIMAITMLSALFLILGNLVADILYLLIDPKIKSSKGGF"
     gene            26864..27676
                     /locus_tag="KR231_001852"
     CDS             26864..27676
                     /locus_tag="KR231_001852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBH0004229.1"
                     /translation="MFTSILKKLKKDKSFAFACITLSIIIILIIASFILNIDSNAIDT
                     TSKLQEPSLKHIFGTDELGRDYFSRALYGGRISLSVGILSMLISVVFGTAVGVISGYI
                     GGKLDQFLMRLIDMLMSIPSFLVLIVLNTYLTPKVSTIILIIGFLSWMEVSRIVRGET
                     LKIKENEYCLAAKATGIKTRNILLRHIVLNLKETIVVAGSLNIANAILTESALSFLGL
                     GIQLPLASWGNMLQDAQRHIFDKLYLAVFPGLLIFLTVMSLTIISKKFSSNT"
     gene            complement(27892..28794)
                     /locus_tag="KR231_001853"
     CDS             complement(27892..28794)
                     /locus_tag="KR231_001853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HBH0004230.1"
                     /translation="MDIKQLKYFVEIVKSGFNLSIASKTLHISQPALSQIIKNFEESE
                     DVYLFERYKGRLNGLTPAGERFYVNAEHIINEYKNMMEDLREDSVQFKGKVRIGIPPL
                     ILGIAFSDVVAQLVANNPDIEFDIVEKGAYDLNRMLILQELDYAVLLHPHKIDKSVVT
                     EHVLQEDELTAFLNINHPLAKKDKIDWNDLNEQLLAIFNPTFMIHHKLMQKFTDENVK
                     LKRYIMSGSWDFLLLSTTNSDFITILPSPVHDFFENSKIIEKPFNHPITWKVILCRPK
                     KERYSHVDQHVFKFIIDFFSKKNS"
     gene            29149..30327
                     /locus_tag="KR231_001854"
     CDS             29149..30327
                     /locus_tag="KR231_001854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000786547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA C-acetyltransferase"
                     /protein_id="HBH0004231.1"
                     /translation="MKDVVIVSAVRTPIGSFGGVFKNTSAVQLGTITVKEAISRVGLN
                     LSEIDEVIIGNVLQTGLGQNVARQIAINAGIPNSVPSYTVNKLCGSGLKSVQLAAQSI
                     TSGENDVVIAGGTENMSQAPYIVPTARFGSKMGDITMVDSMLTDGLIDAFNQYHMGIT
                     AENIATKFEFTREMQDKLALESQSKAENAIKNNRFKEEIVPVDVLIRRGKIETIDKDE
                     YPKLGMTFEGLAKLKPAFKKDGTVTAGNASGINDGAAMLILMSQQKADELGIRPLAKI
                     KSYASAGVEPEVMGTGPIPATRKALKKAGLSINDIDLIEANEAFAAQALAVKNELQID
                     SSKLNVNGGAIALGHPIGASGARILVTLIYEMQKRKVETGLATLCIGGGQGISMVVSR
                     "
     gene            30336..30992
                     /locus_tag="KR231_001855"
     CDS             30336..30992
                     /locus_tag="KR231_001855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA transferase subunit A"
                     /protein_id="HBH0004232.1"
                     /translation="MNKIVSIDEALSHVKDGDTIMVGGFMANGSPENLIDYLCSKNIK
                     DLTLICNDTGFIDKGVGKMVVNKQFKKIIASHVGLNKETGRQMNNNETDVELVPQGTL
                     AEQIRAAGYGLGGILTPTGIGTLVEEGKQKIVVDSKEYLLEKPIYADVALLFASKVDK
                     AGNLVYKGSMNNFNNLMASAAKITIVEADEIVEIGDIDPNEVNTPGIFVNYIIEGGNL
                     "
     gene            30992..31657
                     /locus_tag="KR231_001856"
     CDS             30992..31657
                     /locus_tag="KR231_001856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacid CoA-transferase subunit B"
                     /protein_id="HBH0004233.1"
                     /translation="MDKLEMQEYIANRVSKELKDGAVVNLGIGLPTKVANYIPDNVNV
                     ILQSENGFLGLGSAEDGNSSDETIVNAGGQPVTILPGGCFFDSATSFGIIRGGHVDIT
                     VLGALQVDKYGNIANYMIPGKMVPGMGGAMDLVTGAKKVIVAMEHTSKGSAKILNNCT
                     LPLTATNAVDLIVTEMGVMEVTSDGILLKEINPAFTLDDVISATEAPLILSDSLNGKI
                     SVV"
     gene            31762..32538
                     /locus_tag="KR231_001857"
     CDS             31762..32538
                     /locus_tag="KR231_001857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxybutyrate dehydrogenase"
                     /protein_id="HBH0004234.1"
                     /translation="MVKDKVVFVTGAASGIGKQIAESFLKNGAKVMFSDINQEALNNT
                     ITELQKKGYDCMSVKCDVTKEEEINHAIDKTVEKYGRLDILINNAGLQHVSMIEDFPT
                     DKFEFMIKIMLTAPFIATKKAFPIMKKQGFGRIINMASINGVIGFAGKAAYNSAKHGL
                     IGLTKVAALEAADSGITVNALCPGYVDTPLVRGQFNDLSKTRNIPLENVLEEVLYPLV
                     PQKRLLDVQEIADYAMFLASDNAKGITGQACLLDGGYTAQ"
     gene            32600..33934
                     /locus_tag="KR231_001858"
     CDS             32600..33934
                     /locus_tag="KR231_001858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntP family permease"
                     /protein_id="HBH0004235.1"
                     /translation="MSIIAPIGIIIGIIAIIYFSVKEIHITIAAPIATLIVVILNKMD
                     VVTSMLGADKNNYMGALGNYIMSYFAIFLLGSILAKFMEESGATVSIADFILNKFGSN
                     HPYRVLVAIFIVSFILTYGGISLFVVMFAVIPLARTLFKKLDISWNLIQIPLWLGIAT
                     ITMTIIPGTPAIQNVIPIQYLNTSLTAATIPSIVGSIGCATFGLVYMKYALNKSIRKG
                     ETYATYTSELEEESLDRELPGFFASIFPLLALVIIAITGSTFGSEFMKKNVIYIALIV
                     AILLSAFLFHKFLSSKIQTLSIGASGSIGPIFATSSAVAFGAVIMAAPGFDVFSKLIM
                     SIPGSPLISLTVLTSTMSAITGSSSGALGIVMPNFADYYLSTGLNPELIHRVATIASN
                     ILTIVPQSGVFLTFLSLSKLTHKTGFKETFIVVAVGSLIAEIIVITLGLLMY"
     gene            34430..35326
                     /locus_tag="KR231_001859"
     CDS             34430..35326
                     /locus_tag="KR231_001859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sporulation protein"
                     /protein_id="HBH0004236.1"
                     /translation="MMRRNIPTKLKTILALGVLTLATASSAVTASASSLENNVNISNK
                     SLVYSNTKYKFSAKPNCSVKPELKPDKDNSCKDKNHNDKNCNNTNKPEDNNNSDSTNK
                     PGNNKPESNKPEDNNNSGSTNKPDNNKPESNKPEDNNNSGSTDKPEDNNNSDSTNKPD
                     DNNNSGSTSESFSAYQKEVVDLVNIERAKAGLNPLTLDSSISNVATKKSQDMIDNNYF
                     SHNSPTYGSPFDMLKKFGISYKTAGENIAMGQKTPKEVVNAWMNSEGHRKNIMNPNFS
                     KIGVGVAQKSGGSIYWTQIFVG"
     gene            complement(35718..39257)
                     /gene="nifJ"
                     /locus_tag="KR231_001860"
     CDS             complement(35718..39257)
                     /gene="nifJ"
                     /locus_tag="KR231_001860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009900447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate:ferredoxin (flavodoxin) oxidoreductase"
                     /protein_id="HBH0004237.1"
                     /translation="MAKFMKTLDGNTAAAHVAYAFTDVAAIYPITPSSTMAEVVDEWA
                     SQGRKNIFGQTVNVVEMQSEAGASGTFHGSLQGGALTSTFTASQGLLLMIPNMYKVAG
                     ELLPGVFHVSARALASQALSIFGDHQDVMAARQTGCVLLASGSVQEVADIAPVAHLAA
                     IEGRLPFIHFFDGFRTSHEIQKVELLENEDYASLLNFEAVQAFRDNALSPNHPVARGT
                     AQNPDIYFQTREASNKYYQNIVGIVEKYMEKMSNLTGRKHSLFDYYGAEDAKYVLIAM
                     GSVTETIEETIDYLNAKGEKYGLVKVHLYRPFSMKHFLDAMPSTVERICVLDRTKEPG
                     STGEPLYLDVRDVFYGKENAPMIIGGRYGLGSKDTTPSDIKTVFDNLVSEQPKNGFTV
                     GIVDDVTNTSLTPSEPIKIASKGTIRCKFWGLGSDGTVGANKQAIKIIGDHTEKYAQA
                     YFDYDSKKSGGITMSHLRFGDTPIRATYLIDEADYIACHKQSYVYQYDLLKGLKKGGT
                     FVLNTIWDQAGLEEHLPAHMKQYIAKNDIKFYTVNAVKLGQEIGLGNRINMIMQSAFF
                     KLAEIIPEEDAVKYLKDSIVKAYGKKGEKIVNMNYAAVDAGINALVKVEVPASWENAV
                     DADKGEVKEPEFIKNILRPMTAQEGNNLPVSTFNGIEDGTFPCGTAAYEKRGIAVDVP
                     EWIIDNCIQCNQCSFICPHSCIRPVLVTEEELANAPEGFEAKKALGKGLEGLKYRMQL
                     SPLDCTGCGNCADICPAKEKALVMKPIDTQLDTELDNWAFAVNPDEVAPKGDVMPANT
                     VKGSQFRQPLMEFSGACAGCGETAYIKVVTQLYGDRMMIANATGCSSIWGASAPSIPY
                     TCNHEGKGPSWANSLFEDNAEYGFGMYTAVKQIRNKIVDAMTELVSMDICEDAKAVFT
                     EWLDSRNDGEASKVASAKVVELLEKPACDCTDEKAKELVKAIKDRKDYLVKRSQWILG
                     GDGWAYDIGYGGLDHVLASGEDVNVLVFDTEVYSNTGGQASKATPAAAMAKFAASGKK
                     SRKKDLGMMAMTYGNVYVAQVAMGADKNQFIKAVIEAEKHDGPSLIIAYAPCINHGLK
                     EGMGRTVANEAQAVACGYWHLYRFNPEVKAEGKNPFTLDSKEPTASFKDFILAQVRYS
                     AIAKQFPEEADGLFAKAEADAKERYEGYKKLAE"
BASE COUNT        13481 a         6442 c         5388 g        14216 t
ORIGIN      
        1 tataaaacta ttacctataa agtttataga atcaaagcac ttaataaatg accctatttt
       61 tttcttttta gttctctcaa actcttcttt tgataatcct tctttttttg atttttctat
      121 ataatcaaga attatttctt ttactttttt aggctcttta gaatctccag ctattatgct
      181 aaaagcataa tccacttgag acgaaaatcc agctccaaaa ttttcattta ttaaaccttg
      241 catatacaaa tcttcataaa gcttacttcc ttttttaaat aacatcccta caagtatatc
      301 agttacaatc tctttacgta aaagttcttt cccttttaaa ccaacattac tatctttaaa
      361 acctatgttg aacataggca tagatatagg gaatttttct ataacctctt tttcttttac
      421 accttctggt tcttctggat aaaatctttc tatactctta gagagtttat ctactttgta
      481 attgtttgac tttttagtta catctataac tttttctaca tctaagtcac caacaacaaa
      541 taaagccata tttcctggat tatagaaagt attataacat ttatatagct cttccttagt
      601 tatcttatat atactatcaa cagtacctgc tatatcaatt ctagcaggat aatttacata
      661 cattgccttc aagcaattaa agtatacatt ccaatcaggg tcatcattgt acatttttat
      721 ctcttgtgct attatacctt tttccttttc aacattttca tctgtaaaat aaggtgtttg
      781 aacatagtca attagatgtt ctaaactctc ataaaaattt tcagtagcag aaaataagta
      841 ggctgtcatt gtaaaattag taaatgcatt tgcatttact cctaattttg aaaatttatc
      901 aaatgcatct cctccatcag gttgctcaaa catcttatgc tctagaaaat gtgcaatacc
      961 ttcattcact ctaattttct tatcttctcc aattggtaca aattctaagt catttgaacc
     1021 ataattagta gctaaaatag catacttttt cataaaaccc cttttaggca taaaatatac
     1081 atctaatcca ttttgcaatt tctcataata aacttcttct ttcaatatat cattaactat
     1141 tttttccata gacatctcct ccattaattt ctcaagaagt atacagtatc aagctctata
     1201 ttttttatag cttcaactat atcttttttt gtaacctttt ctatactaga tattatatct
     1261 tgtacttcag aatttgtctt tgccatagat tgagagaaaa caaaatcaga cataccacct
     1321 atattatcag ttatagattt catagaatta actaaagcaa gtttactgtt ttctaattct
     1381 tcatcagata tatcacctgc ttttacactt tctacttgtt tttttatcaa ttctacagct
     1441 ttatcataat ctttagtttc tataccagat gatataaaca tgatactttt atacttctct
     1501 attgaagaga atatatagta acataaactt tctttttctc ttacattaac aaataattta
     1561 gagtgtggac caccacctaa gacattgctc ccaactacta aagcataata tttatctatg
     1621 tctgcataat ccacatttgc tctataaccc ataactaact taccttgagt tatttccatt
     1681 tgttcatcta taacttttac ctcatccaca ttttttataa aatctgctct tggtatattt
     1741 ataatttctt ctctttcaaa ttttagattt ttacttatta tatctacaac tttatcttca
     1801 tcaaaattac cttctacaac tatatctata ggtgatgttt taagtatgtt tttataatgt
     1861 tcatataact ctcttgaagt tatactatct atttcatctt cataaccaaa ttcacttaca
     1921 ctatatctct ctcctttaca catagcctca atacatttat cttgcgcata ttccttttta
     1981 tcatttatta ttgattgtat cttttctctt aaattctctt tttcaatatt taaatattct
     2041 tctttaaacc caccatctac aacaagcgta ttatttatta cttcattaaa aaattctact
     2101 acttcttcaa atatactctc atctaaatac ttttcactta tgttaattac tttaaaactc
     2161 aatacttgac gttctccacg ttttacagca tcagctccca tagatgaacc gtataaatca
     2221 tctaatttat tggatattgc tctagcacta ggatatttag agcttccact tgctattatt
     2281 gatggtatta gagcattttt tgtagtttct ttttcatcca atagtctctg aacatataaa
     2341 cttataagat tcgatttaaa cttttctgtt tttatcaaag taagattaat attattacct
     2401 aaatttatta tttttttagt attaaccata tgtacctcct atttttattt aaacatcaat
     2461 tttaaaattg aaatttattt attttttaat tacatatact cacatataaa aaccttctat
     2521 ttaattatat cctttttatt attttctaaa agcaatattt ttatttaaat taaatacaaa
     2581 tattatttaa atcaatatgc tttaaagtct agtttacaag cttgatatat atgatgtata
     2641 atcaatatgt atgtctataa ttaaaacaat tttgcaatcc tatagattga ttgtttaaag
     2701 ttatataaag aatataaaaa agaataagag agaggacgat taatatgaaa ttaggtatag
     2761 ttggtttacc aaatgtaggt aaaagcacac tatttaacgc aataactcaa gcaggtgcag
     2821 aatctgcaaa ttaccctttt tgtacaatag acccaaatgt gggagttgta tctgttccag
     2881 atgaaagatt aaacaaacta caagaattat ataattctga aaaaatagtt cctactgcta
     2941 tagaattttg tgatatagca ggtttagtta gaggagcttc taaaggagaa ggtttaggaa
     3001 ataaattctt atcacatata agagaagttg atgcaatagt tcatgttgtt agatgttttg
     3061 aggatgaaaa tgttgtacat gtagatggtt ctgtagaccc acttcgtgat atagaaacta
     3121 taaacttaga attaattttc tcagatatag agattcttga aagaagaatt aataaaactc
     3181 aaaaagctgc taaggctgat aaaactttag gttctgaact tgatttatta aaatcaataa
     3241 tgtctacttt agaagaaagt aagtgtgtaa gaactatgga atttacagaa gatgaacaaa
     3301 cattcgtaaa ttcattggat ttacttacat ctaagcctgt aatatatgct tcaaatgtat
     3361 cagaagatga tttagctgat aatggagaaa ataataaata tgttcaacaa gttaaagcat
     3421 ttgcagaaac agaagatgcc gaagttgttg tagtatgtgc acaaatagaa gcagaaattt
     3481 ctgaacttga ttctgctgaa gaaaagaaag agtttttaga aacattaggt cttgaacaat
     3541 cagggcttga taagcttata aaatcttctt atgctttact tggtttaatt tcattcttaa
     3601 ctgctggtcc aaaagaagtt agagcatgga ctataaaagt tggaagtaaa gctcctcagg
     3661 caggaggaaa aatacattct gatatagaaa gaggatttat cagagcagaa acaatagcct
     3721 ttaatgattt ggttgagcat ggtactatgg ctgctgctaa agaaaaaggg ttggttaaat
     3781 tagaaggtaa agaatacata gttaaagatg gagatgtaat attatttaga tttaatgttt
     3841 aaaatgatta atcgtataca ctttgactat tatatataat aactaaaaaa ctaagattat
     3901 aataatacaa tattacctta taataattat atagaattta aaaataaaag aagagtattt
     3961 caaatgattt gtataaatga ttatgaaaaa ctcttttttt gatataataa aattacttac
     4021 atatataaca tttaaattta taaattatat ttttattttt taaaatatgt ataacacacc
     4081 tatagaaatt actattatta ctatctaaag tattttgcta taatcccata tactcttacc
     4141 tcaaaaacat tcaaatgtaa aaaatactac atattaataa actttgccca ataattccta
     4201 aaataatatc ctaacaatga tttatgtttt tataatagta tatttttaca taaaaaagtg
     4261 aacattgatt aacaaagttc acttttttat aaatttttat gttataattc acaattttat
     4321 ttaatttgtt tcttttctat ttaaactata tctatctaat attaattttt catattcttc
     4381 tattggcatt ggtctagcaa ataaaaatcc ttgggccata tcacaaccta taaaccttaa
     4441 aaactctgct tgctctacag tttcaacacc ttctgaaaca acttttatat caagttgctt
     4501 tgccatttga acaatacttg aaactacaat ttgactcttt tttgcatttc ccactgttat
     4561 aaagaattgc ctatctaatt tcaatacatc aattggcata tctttaagca tatttaaaga
     4621 agaataacca gaaccaaaat catccataga aattttaaat ccaacagatt tcaaagtttg
     4681 cattatttta aataatattt ttgtattgtc aaatattgca ctttctgtca attcaatctc
     4741 aattaaattt ggttcaattt catattcttt tgttattctt tcaagctcag aaataaagcc
     4801 tggattctca agatgtactc ttgataagtt tattgatata ggaaatgtgg ggaaattttc
     4861 attttcccaa cgtttaaaat ttttacaaac ttgggtaaat acaaacatat ccaattctgt
     4921 tataaagcca tttttctcaa aaataggaat aaatacacct ggacttatta gacctttttt
     4981 aggatgttgc caacgtacaa gtgcttcagc acctacaatt ttagtagttg ataaatcaac
     5041 cttaggctgt aaataaactt taaattgttc attttttaaa gcatcatgca tttcttgttc
     5101 aatatcacgt tcttctatga gagtttcttt taaattttca gcataaatct cataaacttt
     5161 taaatatttt ctttttactg tagtttttgc aatcatagct ttgtcaagac aggtagaaat
     5221 atttgtttct ccctcttcaa caaaatatac acctatggat ggaattaaat tgagttctac
     5281 tcccaaactt gtttttatca ttgacaattt tttacgtata agttcacata tttctataat
     5341 tgactctcta ttatttttct tttcaaatat tatagcaaaa ttgtcatttg aaattcttga
     5401 aaatacagat tgctctttaa atatattctt aattatctct gctatttcct ttaatactct
     5461 atctccttct tcatacccaa acctatcatt tactagctta aacttatcta tatcaaaata
     5521 aattaaaact agattctttt tctcatgaga ggataaaaat tttccccctt caagattaaa
     5581 tttatttgaa ttgccaatac ctgtaacgtt atctttaaaa gcaaattctt ccaatttttc
     5641 cttactcttt ttatgtataa atagtatata aattgttaat gccgtaaaga ttataatcaa
     5701 gactacacat gctgataatg taagttttat aatagcatat gatttctcag atatagcagt
     5761 tttaggaact tcagaaaaaa gataccaatc attgattcct attggggcat aacttaaata
     5821 atatcctttt ccaaacatac tataacttaa tgaacctgat ttaaagtttt ttatatttga
     5881 cttcatattg ttgatactag attttgatat tgaatcactt ctgccaatgt aagaaaataa
     5941 attttcttta gtagagttgg cgtttttact gcttggattt aaaacaatat caccattact
     6001 tctagttata taagaatatc cttttccatt aaatgtaggt acagaaagta ttttttcata
     6061 caacttcgta ctatgtgtgg caaatataac tcctttaacc tcattatctt tataaattgg
     6121 tacagaatat acattaatat tactattggt atttttatca tcttctatta catcttttaa
     6181 tttgcctgtt ataaccactt ctccttgcat tgattttaag aaataatctc ttttagagaa
     6241 gtcttctata taaccatctg tagtgtatgc tgtaccattt ggtaaaataa ctcccattct
     6301 tttaaatgaa ctattaatag cttgtctttt tagtatagaa aggatattat ctacttcaaa
     6361 agactcttct ccttcaataa atattgaaat tgactctagt aactttatat ctccattaat
     6421 ttgttttttt aacacattga cactttgatt tgctatttct gaaagatatt gattcgtttc
     6481 ttcacctaat gtcttattca accttgaacc ataaatcaaa caggaaattg taattactaa
     6541 gatacttatg acagcaatta tggacaaacc atacctatta ttttttgcat cacttaacat
     6601 tatgcttcct gcctttctcg aatctatgta tgtataatca ttatcttatg acaattattg
     6661 taaacatttt ataataatac ttatttttcc atatttactg taattataca aaattataaa
     6721 ctttattaca acaataaatt aattaatata gatattagtg tttatattat tgcattatct
     6781 attttacaat tatttacata taaaaaaatg taatatcaaa gtgaagcttg atattacatt
     6841 tttgttcttg tattttgttt aatttttatg ctacatctta cttaaacact catttgcaac
     6901 ttctttatca tcaaaatgat gcttaacttt acctataatt tgataagttt catgtccctt
     6961 acctgttata attacaacat catccttttt tgccatactt atagcttctg ctatagcttg
     7021 ttccctatca acaacaacat ggtaattttc ttttttcttg tcaattcctt caagtatatc
     7081 ttttattatt gcctctggtt cttcagttct tggattatca gaagttataa tacataaatc
     7141 agaatatttt tgtccaattg ctcccatcaa aggtctcttt tcagtatctc tatctccacc
     7201 acacccaaac acagaaatta tttttccttc tgcaaattgt tgagttgtct ttagtacatt
     7261 ttcaagtgcg tcaggagtat gagcatagtc tacaattacg cttatacctt tatcatttgg
     7321 aactgtttca aaccttcctg atactccatt agaaagtcta aggccttctt tatatattgg
     7381 tttaggtatg ccaagtacat agcaagcagc tataactgct aaagtattgt atactgtaaa
     7441 cattcctgga actggtataa atattacttc ttcatatgaa ggtgttatta atctataaga
     7501 tactccatcc gaatctgatt ttatatctct agccataaaa tcagccttag tatcaacacc
     7561 ataagtgtaa caaggtacat ttataccttt tatattttca tatatctttt ttccaccttc
     7621 atcatctatg tttattatat ttgccatagt agtcttaaaa aataattttt cttttgcttt
     7681 tctataatcc tctaaatctt tatgaaaatc taaatggtct ggtgttaaat ttgtaaatat
     7741 gcctagttta aagtctgttt catcaactct atttaatgcc aatgaatgtg atgaaacttc
     7801 catcgcacag tagtcacatc cattatccaa catattatta aaatgatatt gtaaatctat
     7861 actttctgga gttgttgaat tggaaacaat gtctttttct ccatcaaaaa tttttatagt
     7921 tcctataagt ccaactttat tcttatttaa agttaatatc tcatttagta tagtagttat
     7981 actagttttt ccattagtac ctgtaactcc tataacgtta aatttttgag atggatgatt
     8041 gtaaaaatta tcagctactt ttgccatatc ttttcttgta tcttttacct ttataaatgt
     8101 acatcctttt atttctacat cttcttcaac aagaaatgca cttgctccct tttctatggc
     8161 atcttttata tacttatgac catctgacac aaatcctttt atacatataa ataatgtacc
     8221 ttttgtaacc tttcttgaat catattgtac attattaata tctatattta attcaccctt
     8281 gatattgatt atatccaacc cctgtataat atcatttaat ttcataaatg ctttcctccc
     8341 tttaaactct ttctgctaaa attacactac atataatatt atattaagaa ttttttacta
     8401 tgtgaatggt taaaaatgct tgaaacattg caaaaaatgc tctataattt tctataatat
     8461 aactgaggaa aggtcttcta taaaaactat ggataataaa atcgggtact taaacgataa
     8521 ctttaaaata tttaatatta gagataaaaa agatatacaa tttgaatacc ataatcatga
     8581 ttttaataag ataattatat ttataaatgg aaatgtaact tattttgttg atggtattcc
     8641 ctataaacta aagccttggg atatactctt tatcagcaat aatgaaatac ataaaccagt
     8701 tatagattca aatgtctttt atgagagaat tgcaatatgg attagcccag aatttatgaa
     8761 aaaaaatagt gatgctagta gtgacttaga aaaatgtttt aaaatagcta cagagaataa
     8821 atgcaataga ttgcgtttaa atatacatga tattgaatct attaagagtt ttattgagca
     8881 aataaatatt tccgaatcca atactgaatt tggaaatgaa atattgagaa atgcattatt
     8941 tatacaactt atgatattct taaacagaat tttcctaaaa aatgaaaata tggaatcaac
     9001 agaagatgtt ttttatgatg aaactattaa gaaagtatta aactatataa attcaaatat
     9061 agatgataag ctttcaatag atagcatatc gtctgaattt tttataagta agtattatct
     9121 tatgagaaaa tttaaatctc atactggaac gtctatacac aattatatag ttcaaaaaag
     9181 attaattttg gcaaagtcac taataaccaa tggtcacctt atgagtgaag tttgtaataa
     9241 atgtggattc aacgattatt ctagttttgt aagggcattt aaaaaaaact acggggtatc
     9301 tcctaaaaat tatataaaca ataaaaatcc tttggatatt actcttttag atgaatagat
     9361 aatttatgta aattttattt taataaaact tgaagtatta gtgtatttat cttactaata
     9421 cctcaagttt tttaatgttt taaaatatat caaaatataa tgatatatat ttctattact
     9481 taaaatatat attaaataaa ttgcatgtta actgaaccta tttatatatt tattaaatcc
     9541 cacataactt ttagttacac tatcatatag ctatcctatt ttttcaatat catctcttaa
     9601 tatacttact ctattctcct cttttgctgt gcttactcct tttttaatgc ttaatttctg
     9661 attttgttct aaattcgtaa atactacagg acttattgtt gatagaccat ttttttcaat
     9721 atattctaag tccattttaa ctaatttttc tcccgctttt acttcatccc ctacattcac
     9781 aaatacttca aatccatttc cttctaaatt tacagtttct atccctaaat gtataagtat
     9841 ttctactcca cttttttggg attttattat tattgcatgc ttagttggaa atataactcc
     9901 aatagttcca tcaactggtg aataaatcaa tccatcacta gatttaattg caaatccatc
     9961 ccccatcagt ttacttgaaa atacagaatc tggcacttct tctatatcta atatctctcc
    10021 atttgttaat gaatcaatct tttctactaa agcattttcc atatttgcaa cttccatatt
    10081 ttttttcact ttatttttat caacattttt agtaacagta ctttcaacct ttgtttttcc
    10141 ctctattata tcttttatat cagactttat tgaatccgat tttggtccaa atatagcttg
    10201 aacattgttg ccaataacca taacacctgc tgctccaagt gatttcaatt tttctttatc
    10261 tactttattt atatcattta caaccaatct aagtcttgtt atacacgcat ctaggctctt
    10321 taaattgtct ttatttccta aagcaatcaa aatctctgat gctaattcat tcttagacat
    10381 ttcaatgact tcagcgttag tttctgactc atcttctctt cctggtgtct ttaaattaaa
    10441 ttttcttatc ataaatctaa atacactata gtataatact gcaaaaccaa tacctaccaa
    10501 gatagccaag taccatggag ttctattagg aagaacacca aataataaga aatctattaa
    10561 tcctcctgaa aatgtgaatc caattttaac tcctaataat tgcataattg cgtatgataa
    10621 acctgaaaat aaacaatgta ttgcaaataa tactggtgca acaaataaaa acgcaaactc
    10681 tattggctcg gttattcctg ttaaaaaaga ggttaatgct gctgatgcca ttatacctgc
    10741 tacaaatttt ttcttttctg gctttgcttc atgcaccata gcaagagctg ctgctggaag
    10801 accaaacatc ataaatggaa atgcacctgt cataaaagta cctgctgtga aatttactcc
    10861 atctttaagt tgagcaaaga atatcttttg gtcacccatt acaagctcac cagctttatt
    10921 tacatattct ccaaattgat accaaaatgg attatggaaa acatgatgca aaccaaatgg
    10981 tattaatagt ctttccaaag aaccttccat aaatgctgct agtgtttgat ttgcttctat
    11041 aacatttttt gagaaactaa gtaatccctc ttgtattgga ggccaaataa aagacaatat
    11101 aattcctatt gctatagcaa ctaatgaagt aacgattggt acaaatcttt tacctgcaaa
    11161 aaaacctaga tactgaggta attcaatttt ataaaacttt ttataaagat aagcagccac
    11221 tatccctata ataatgccac caaatacccc tgtttgaatt gttggtattc caacaatatt
    11281 tgcatacata gaattgtcta ccatatcttc tgtaacacct gccataacac ccatagatgt
    11341 attgagaatt aaaaaaccta ctatggctgc caatgctgca acaccttctc cttcagttaa
    11401 accaacagct accccaactg caaatataag tggtaagtta ttaaatataa tttgacctga
    11461 actttccatt atacttatta taagttgaaa tgtaggattc gccaaagctg gaaaatgagc
    11521 caacaatgcg tctcctgcta aagcattact cacgccaagt aatatacctg ctgcaggaag
    11581 taatgcaact ggtagcatta gagattttcc tactttttgt aaaacaccaa atactttttt
    11641 catttacttt tctctcctta ttattttata tttttttaaa taaaaaagac ttaagtttat
    11701 aaaaagttac attagtatac ttaattctaa aattaaactt atgttaatat aaataaacct
    11761 atattaacct aatttcagaa ttaaaaataa actattataa tttttttata aacataagtc
    11821 ttgcctgcat tatcagtaac aatcttaatg ttttaaaatt attattttat attaaatttt
    11881 aaataatata ttaaaattaa acataatata ttaaatctat acattctgta ttaaactact
    11941 ctttattata aattttatat ctaattttag attatctgca taaacactat acttttaagc
    12001 attttgaaat ataagaaaac actcatttta ccacgaattt accacgattg aatgagcctt
    12061 gatatgacct ataaagtaac accagaaaga catcattata cctaaatggt gtctttttaa
    12121 aaagcagtca atcataagac taactgcttt gtgtgtacag atataaattt ttgaaaactt
    12181 ataaactctt taaaattgtt gctaaatttt ctttatgcca tgaagcacca accattgttt
    12241 tgttcacttt aaaagctaat gttccttgtg atgtactaat ttctaattca taagacatta
    12301 actttttatt gaatttaaca cttgttactt cttcttttgg tacgaaaagg aatgcttcat
    12361 tttctaattt gcctgttaca ttatttaaac cgataacagc aataccgcta tcgccaaaat
    12421 ttattgcgta atattgcatt gaaagagcag ttgcaactgg accgagagca tatgtaaact
    12481 tactagggaa gataacacca ataatagatg tattctcctt aaaggcacta cctttctcgt
    12541 taaggtattg tttaatgtct tgttctttta gcattttaat tgtcctccta taaaattatt
    12601 tttcgcataa cttactgttt tcattttatc atttcaatat agtgattaca atgtatttcg
    12661 tgaaattaca acatcaatca gaatttgttt cattgttcag attttgtttt ttccattcct
    12721 taaaatcttt ttttgtttct tgttgtcttt taacatcttc cattttttcc aaaatcactt
    12781 ctacctctgg ttgactgtgc tgttcgggta gagaatagaa aataaggtta ttatcgtttg
    12841 tatatactga aatattaaaa accaaatcac tttctacaat ttcttgcatg atataggaaa
    12901 tttcttctgc atattcttcg tctgtttttc cctcgttaag atatatactt gtttctattt
    12961 cgtattctct ttttttcaga tattcttcta cactttcctt accattccat tctgttgtgg
    13021 ctgtatgccc ttgaacttca atttgataat ctcttataaa aggcttatct tgaaataaag
    13081 gagttgcaag ttcttttatt tcatcaaaat agtaataaac atggtaactg tcctcaaaaa
    13141 gtccagtatt tcgtgtatat acagtagcag tttgagaaga attttcttta ctggaaactt
    13201 ctgccataat ccagtttaat cctatttttt cttctttgta cttcttcact tctgtaatga
    13261 taaattcttc attgtatttg tcctttaatt tggataagat atatttttgt gcttcttcac
    13321 tagagttaaa atcatgcgaa taaccgctac aactatttaa tagtcctaga caaagcacgc
    13381 ttgctataac acctaataaa atttttttat atcgcataat cgccacctca atgtgattta
    13441 atacaattct acaaactgat agttataagt cagtcaaaaa aatttttgaa atatcttttt
    13501 tctgaagttt gtatttttga acttgggata atggaatttc aaatgctgtg cttgtctttg
    13561 gaaatttatt gttcaatata tcatcataga gaactgtaat aaatctcccc cattctttta
    13621 agtcagctgt ctttgttgaa tcgtctaaga aagcataacc atcacttaaa taaaatatct
    13681 ctaatgctag tgctaaatca caactggagt cagcaagtat ttgttttgga atttcaaatc
    13741 cgtcatccca gttatattca tttagcttac ttctcaaatc attatatatc atttttatat
    13801 tccccaaatt ctaatttgca tgtatgaaat ataggattat aatcttacca ttcatttatg
    13861 gcatacaaaa tagcaagtct tacatttttt aacaactcag aagatagagt ttcgtattct
    13921 tcagataacc cttttttgtg agccatatat gctgggctat cattccacga acccattgct
    13981 ccaaaaacat ccgaaatact tgcagcttcg aacatttgaa gattttgctg tggaattggt
    14041 ggtaaactca aaccatactt ttcatctgga tattcgctac agccatctaa aaggtttata
    14101 gcagaagtaa aaatattagc aaaattttca cactcaattt ttttagccaa ttctttaatc
    14161 gataataata catctcgaaa tgagttaatg ttattctcaa aatatggttt ttttgatggt
    14221 gagttagtcc actcatgctc tgaatataga atattccatt ttttttgcat agagtcaaat
    14281 tgccaatcag cagtaaagta tgttactttt ccgcttttgt aaaaacacaa aatggaactt
    14341 tctgttgtat ttgaaaatcc taaaaattgt ctatccttta ctgaatatgg acatagcaac
    14401 tttatatcct gtatcccatt tttctttatt tgttcaaacc acaatgaaac attagaagca
    14461 gtatattttt ctgtccttaa aaatttcttt tgaggtaaaa agacaaattc aattttattc
    14521 tcatattcta attgtgaaaa tctaattggt tctgataatt gcaacgcttt tttgctcgtc
    14581 gctacaatag atgcaatttg aaacatttgt ccattcatca tttcgcctcc ccttaatatg
    14641 aataatactg ttctttcaaa aattctaatt tgtcgctttt ttcatatcca tattataaca
    14701 gttccatata tctgccacaa taaaaatcaa catacccttt aaatattttc tgcattgaac
    14761 atacacactt tttctttctt cctcttgatt acccaccaca gaaaagaaaa agccctgtca
    14821 agagccttgc caccattggt ggtgctttgc actctttact gggctttttg tttgctgtat
    14881 cttccatgca agaggaaatt aaagacctct gttccatttc gcctttagat aatcttcata
    14941 atctccctca ttaaagtcta cttgtggaga agtattagga atattttttc tgttatctat
    15001 atctgcaagt tgacggaata tccagtcatc ataagggttg tgatatttgt attctttcgg
    15061 ctgttctctg tatcggtcta accctcgcat ttccttatgt actttcatca tgcgttctat
    15121 tttttgacgc tgtatcaact gtttgatttc cataagttct tcaatttcta caacctcatt
    15181 agaaagataa ttgctgatgt atctaatcaa tatggtttcc atgtaaaatc tgtattcgtt
    15241 ttcattatcg aaaaattcat tttcagacag ataatctaaa gaaacattga agtcctgttc
    15301 ccgtttgata atatccatga tatatggctc ggtgtggtcg atatacttcc attctcccga
    15361 caataattca ttgggcgtta ctcccagcac gtccattatc ttttccagcg tatcaaaggt
    15421 ggggtaattc acacctcgtt caatcttgga aaggctctgc atattgatac cgattttgtc
    15481 cgccagttcc tgttgtttca ttcctctgtg ttttcttatg gtctgtatgt tttctcctaa
    15541 gaaactgatt ttcttttcgt aatgctccat gacttagtat aaacactcct ttcattgctt
    15601 ttcttggtat ttataagcat atcatactta atatatatca aaaagtcaac aaaaaattct
    15661 tgacaagtaa ttctaatggc gttattatcg tatcagatag agtgattaag cacaataggg
    15721 tcaatcacac gcttgagtaa gcatagaaaa gatgtgtttt cattttgata gcatgaataa
    15781 gcatggacta tcagaccgaa aataaggttt ctgactgggg ctgttccgtt tagccacgag
    15841 ccttacaagg ctcgtgagcg ttaagaacgg atcagacaca ggaagaaaag gaacgccttt
    15901 aggcgttcat aaagggcgta tatgtaacac cgccctgcgc atacatgtca tagtacctag
    15961 aaactgtgat aaataaagga aaaaacacga tttttacccc gcaaaaaaac gggaagtacg
    16021 aaaggagaaa tgcactataa ctacacacaa aaatttatcc gttaagattg attacatcag
    16081 tattgtattt gatactgcaa ccgctgaaga tgtaatcatg cacattttag gtttaccgac
    16141 tgacattttc aatgtctatc cggcaagcat taaatacaaa acctatcaag cacgctggca
    16201 gattggagat atttatgtat cgggggacgc aagaaaaaca gaggataacc cacagggact
    16261 aggctgttat cttgttatga ctggcagagg ttgtgatgat attttccgta ttctcgacag
    16321 taggaattat acctttgggg atatgttccg acgctgtgag cgaagatacg gactggataa
    16381 cttccacttc acaaggcttg atattgccat tgatgataag aacgaaaagc cattctttac
    16441 catagagcag ataaagaaga aatgcgaaaa agaggaattt atctccaata gtgagggcta
    16501 ccactttgat gaaagcaagt ttgacgattt cgacaccgca aagactgttt atatcggtgc
    16561 tggaaaatct ggattatcct accgctttta tgataaggat aaggaagtct gttcaaaaca
    16621 taataagacg cttgaggaag tcggcagttg gaaacggaca gaaatgcaac tgcgtgatga
    16681 taaggctcat gcctttgcca tgacatttaa agacagaccg ctagaacttg gggaactggc
    16741 tttcgggcta ttggcaaaca acctacgctt tgtcgtgcca aacagaaacg aaagtaataa
    16801 aagcaggtgg aaaacgtgtc gattttggga acgcttttta ggggctgtgg aagtcttgaa
    16861 actgcaagta ccaaaacagc aaaattccct tgaggaaaca cagcaatggc tcacagaggg
    16921 tggcgtgatt tccgctgtca aaagttttta tttcttagaa gaacatgacg cattaggtgg
    16981 actggaaaaa gtaggaacta tgcttgataa ggcaagatac agcaattccc tttccagtaa
    17041 attaaccgcc catttacaga ggataaaccg caccgacctt atcccctata tccagtatga
    17101 cacgaaacat gggaaagggg gtatctgatg aagaacaacg atattcccgt atgggaaaaa
    17161 tacaccctta ccattgaaga agcgtcaaag tatttccgta tcggagaaaa caagttaaga
    17221 cgattggcag aggaaaacaa ggacgctggc tggctcatta tgaatggcaa ccgcatacag
    17281 attaaacgcc gacaatttga acaggttatt gataaattgg acgcaatcta atgcaaatga
    17341 gccttgtatg tgttatgatg aacacaagtc atatcaaggc tctttccaac aaggaaagga
    17401 gcagacacca tgaaagaaaa aagacgggat aacaaaggtc gtatcctgca tactggagag
    17461 agccaacgaa cagacgggaa atacttatat aaatatgtgg acgcatttgg aaacacaaaa
    17521 tatgtgtatg cttggagatt gacacccaca gacccgacac caaagggaaa acgggaaaaa
    17581 ccctcacttc gtgaactgga acagcagata agacgggata ttgaggacgg tatcgacagc
    17641 acaggcaaga aaatgacgct ttgccaactt tacgccaaac agaacgcaca gagggcaaac
    17701 gtaaagaaaa gcacaatgaa acaacgggaa caactcatgc ggttattgaa agaggataag
    17761 ttaggtgcta ggagcattga tacaatcaag ccctctgacg ctaaagaatg ggcgttacgc
    17821 atgaaagaca aaggcttttc ctacaatacc attaacaatc ataaacgctc gttaaaagcg
    17881 tcattctata tcgccataca agacgattgt gtaaggaaaa atccctttga tttcaagtta
    17941 agtgaagtcc tagaaaatga taccaaagag aaagtcgcat tgacagagga acaggaacaa
    18001 gtcctactct catttatcaa gacggacaat gtgtatcata agcattatga tgatgtgcta
    18061 atattattaa agacaggact tcgtatctcg gaactgtgcg gactgacagt agccgatatt
    18121 gatttcaaga atgaagttgt gattatcgac caccagttac taaagagcaa ggaacagggc
    18181 tattatattg aaacgcctaa aacaaagagc ggaataaggc aagtgccatt aagcagagaa
    18241 acgatacagg catttcaacg ggttatgaag aaacgcccaa aggcagaacc atttgtgata
    18301 gacggacgga gcaattttct gtttgtcaat cataaaggca agcccaaagt tgcgattaat
    18361 tataacgcct tatttatccg tatggtaaag aaatacaaca aacaccacaa ggacaatccc
    18421 ttgccacata tcacaccgca tacgctacgc catacattct gcacaaggct ggcaagcaag
    18481 aacatgaacc cgaaagattt acagtatatc atgggacatt caaacatcag tatcacaatg
    18541 aactggtacg ctcatgcgtc catagacacc gcaaaatcag aggttcagcg tctaatcgca
    18601 tagaagtatt taccacgatt ttaaccacga ttgataggga aaatataaga agatagacct
    18661 agatatgtga ggtttaccac aaaagaaaaa tgcccgtaga gccgataaaa taaggctttg
    18721 cggacattta agaagatata aaaagatagt caaaaagaca tatataattt attataaatt
    18781 cagtacagat ataactcttt tgatatgtaa tgttaaataa agtagttcat cttgacttac
    18841 atagtaatca taattctttt ctacatgagt ttttatttta tatgcacaat cataatcctt
    18901 ttcatacttt actttaatta tatctataat ttcattattt gtatcattga ttttttcttt
    18961 ttttactaat cgttttgcaa agaattttaa atgagtcaga agcctatcat aatttatatc
    19021 atcttcttta aattcaactc tataataata tcttataata tttagtatgt cttttacaat
    19081 tttagtaatt aatagtgatt cctttgaact tcccttatag tttgaattta ctatatgcat
    19141 tgctataaaa ccagcttcat ctactggaaa tttcacatca aattctttat ttatataatc
    19201 tacagcccat ttcccaatct catattcttt tttatgtatt ctttttatct catgtagtaa
    19261 atcattcttt atagttatgt tttcatgata tcttttaatt gcaaatgcaa tatggtcagt
    19321 aagtgctaca taaatatatt cataaagctt agtattcaag ttctcctctg cataagcaat
    19381 tatttcagta ctaacctcaa aaaatttctc atcaacctgg cttgctagtt tactaatttt
    19441 atctaaaaag ctttcatctt gtattacaaa agttctttca attttacttt tatctatttc
    19501 ttgacctttc tttttttgaa acccaattcc acatcctgtt aatattaatt ctttttttat
    19561 attttcatct aaaactaata caacattatt attataaatt tgttgaataa tcataatcaa
    19621 tatctctccc aaaatacaat ttcccttatt cataaaaaaa tacctaaatt aagatacaat
    19681 tcacctgtat accttaacct aggtattgcc tgcttaccag taacaatcca gcttgttaat
    19741 gcttatatat tgtattcaat ttatggtttt attctattat aaataaatat atatgtcaag
    19801 taaattattg aaaactattt cctatttttt agtattaatt ttaacatcaa aaatcaaatt
    19861 ttattccatt atatttatga ttctatcatc atcatttcat catagagaat attttccaat
    19921 aactctttag ccacttctct tgatatttgc ttagtttcaa ctaattgttg aacactgtct
    19981 ctttgacttt gtatcgccat tactctgtag tattctactc ttgcctcaaa cttatcatca
    20041 ttttgaatct ttctagtaat ccaattcaaa taacgattat agaatctgat tgctattaag
    20101 gcctcatgtc tgttatcttc atcagtattt ttatttataa atgatatagc agttttagta
    20161 gaaagtgcat atgcatggtg aaactctttg attatttctt tattctcaga tactattttt
    20221 gtaatttttt cttttacttc tttctttact tttctattta taatccacat gcttattttt
    20281 aattttacaa ttttaaatat agatttttga acagattttc ttgattttgt aatataaaat
    20341 ctatacaatt taaaggctct atcagaaatt ttaccatctt ctaatagttt caaaacagct
    20401 aataatccct gttggtctgc ttctgcaatc atcatactta taagtttatt atctggagta
    20461 tttagtattc ctttttctga gtctaccaac tgttcattta aatcatgtat aactggttgt
    20521 acttcttgtg ctttttcatt actaagtttt aaaatggctt ctttcaaaat tagtttatat
    20581 gcctctttat cagataataa aggttctgac tcttgtacgt tattttttaa taatcttggc
    20641 agtaaaattg ttgccaatac taaacttata agaataactt ctgatgatat aaataaaaca
    20701 gtatctctca ttggaaatac atctttatca gccaaataaa aaggtataga taaggcagtt
    20761 gctagtgtaa atgtaccatg aacaccacaa gtagcaacta ttagtgagta tttacattta
    20821 gaaatactct cttttataac ttcttcatcc ttaaaaccta aaaaacctac aaaaaaatta
    20881 tttaaaggat tctttttagg ttttataaaa gaattatgcc ataaatatac ccatataaat
    20941 cttataacaa ataaaataag tacaattaaa gtagaaataa aagtcaattc caatgccata
    21001 ttttcatttt tactactaag tcctgtatat atacttggta acaaaaaacc aagcagtgta
    21061 aagacaaatc cattcaatac atactccaaa acataccaag tattgtctga tattatcctt
    21121 aatttagtag ttgtattttg taaatgctct ttttcaattc catgagctat ccctgccatt
    21181 acaacagcta ggattccaga tactcctatt tcttctgcta caaaatatac aaaaagtgga
    21241 gtcattattt gtataactat taccattgga atttcttcca aattccactt gtgtaaacta
    21301 agtcttattt ttataattat gtatcctaaa atacttccta ctattattcc tccaaaagct
    21361 gtaatcataa attgaatccc tgcctcttct attgaaaaaa ctcctgtaac tgtagcaagt
    21421 actgcaacct taaatgctac tactccagca gcatcattta ataaagattc accttcaagt
    21481 atactcatta tatttttagg aaaatttaat ccttgtgtaa ttgattttac tgctactaaa
    21541 tcagttggag atattactgc tgccaaagca aatgaaacag ataatggcat cccaggaata
    21601 agaaaatgta taaagattcc acctgcaaac acggttatta aaactaaacc aaatgcaaga
    21661 agcaaaattg gttttctaag ctctaatagc tcttttctcg atacattttg tccttcactg
    21721 aatagtaatg gagctatgat acatattaca aatatttctg gattaaatga aaatgagaat
    21781 ttaaatggca aaatagacaa tataatccct agtacaattt gatatattgc aagaggaata
    21841 ttactccact ttttgctaaa tacagttgaa atcgttgtac aaaccaataa tcccaacaat
    21901 gttactaaaa ttgacataac tacctctctt ttcaataata atattataga ttaaacttat
    21961 atatcaacta acttaatatt aacagcatga aatcccatct taatcaaaaa aattttcagt
    22021 ttattctatt attcttatta tatacatcaa atttaatttt tgaaatatct atactagatg
    22081 acatgcaaca aaatgatttc ttgatatttc ttttaaaact ggaatctctt ttttgcatat
    22141 ttccttacaa taagggcatc ttgtatgaaa cttacatcca cttggtggat ttgttggaga
    22201 tggtatgtct ccttttaata taattctatt tttcttaatt gtagggtctt gtattggtac
    22261 tgcgctcata agtgcttttg tatatggatg ttgagaatgt aagtaaagtt ctcctttagt
    22321 tgcaatttct attatagaac ctagatacat aacacaaact ctatgtgcaa tatgatttac
    22381 tacactcaaa tcatgagata taaataaata tgaaagttta tatttatcct gtaaatccat
    22441 aagtaaattt ataatttgag attgaataga aacatctagt gcagaaacag gttcatcaca
    22501 aactataaat tctggattta atgctaatgc tcttgctata cctattctct gtctttgacc
    22561 tccagaaaac tcacctggtt ttctatttaa atggtactta gaaagaccac aactttctac
    22621 aacatttaat atattatctt ttatttcatt ctttggcact aaattatgtt ctataactgc
    22681 ctcggatatt atttgttcca catttaatct tggatttaat gaactatatg ggtcttgaaa
    22741 tatcatttgc attttgggtc ttaactttct aagttcttcc ttctctaact tatatatatc
    22801 tacaccatta aattcaactt taccttcagt tttttcaatt aatctaagaa tggttcttcc
    22861 tgcagttgat tttccacatc ccgattctcc aactatagcc aaagtttctc ctttttttaa
    22921 atcaaaagaa attccatcta ctgcctttac agatttaatt ttcttatcaa ataatccaga
    22981 tttaacttca aagtactttt taagaccttc tacttttaat aaactctctt cttttttcaa
    23041 ttatatctcc tcctttttat ataaccaaca tgcaatacta tgaccactat tcaattctat
    23101 taaaggaggt atctgagttc tacatttatc acatactttt tcacatctat cactaaaata
    23161 acatgaatct ggcattccaa ttggatttgg tacttgtcct ggaatcgaat acaatctttt
    23221 atctttgttt tttccaagag caggctttga ttttagaagt ccaatagtat aaggatgttt
    23281 tggattttta aataattcaa caacctctgc cacttctata attttgccag catacatcac
    23341 taatactttg tcacacattt ctgcaactac tcccaaatca tgtgtaatca tcattataga
    23401 tgtgtttaat ttttctttta tatttttcat tatatctaaa atctgagctt gaatagtaac
    23461 atctaaagct gttgttggtt catcagctat aagtaatttt ggattacatg ataaagccat
    23521 agctatcatt attcgttgtc tcataccacc tgataattca tgtggatatg aattatatat
    23581 ttcttcagct cttggtattt ctaccagttt tatcatatcg attacctttt tcttagcttc
    23641 ttcctttgat aaatcttgat gtatcataat accttcaatg atttgacttc caacagtaaa
    23701 cgctgggttt aaagatgtca ttggttcttg aaaaatcatt gatatctcat tccctcttat
    23761 tcccataagt tcatcttcat tcatctttaa aatgtctttg cctcgaaaga ttatttctcc
    23821 accttctatt tttgatgttg gaagtaactt catcaaagac atggctgtta cagacttacc
    23881 acatcctgat tctccaacta ttccaatagt ttcaccttca tttatattaa aacttacttc
    23941 atttacactc tttacaatcc ctttatctgt atgaaaataa acttttaaat ctttaacctc
    24001 aattagtgct ttactcatta ttttctcctc tcagcaaaat tacttaagat aacatacacc
    24061 ttttgattgt attttataaa aatttaaatt acaacatttt cttacatttt attatttttt
    24121 tctattaatt ataataatat aatagttaat ttctatatat attgatttaa taatgattac
    24181 tattatacaa taaaaaatat gtgttaaata ttattttatg gaggttttat aagaatatga
    24241 aatttaaaaa attggcatca ttaatcttag tttcatcatt aatgcttaca tttacagcct
    24301 gtgcttccaa tgataaagac aagtctagtg gaagcaaatc tggtggaact gttgtaatac
    24361 ctatggcaag tgacccagat ataatcaatg gagcttttgc aaacgttaaa gaagactctc
    24421 ttgcatcaaa tatagtttat gctcctcttt atacttatga aaaaggaaat ttagtaaatt
    24481 atttagcaga aaaagtagat tttaaagata gtaaggaatt aactataaaa ttaaaatcca
    24541 atttaaaatg gcatgatgga aagccaataa ctgctgaaga tgtcttattt acatttaata
    24601 cagttttaga cgaaaaacaa aattcaccat caagacaata cttattggtg ggtgagaaac
    24661 cagttaaagt agaaaaaatt gatgatttaa cagttaagat tactttacca actgcaagtg
    24721 aatctttctt atatggtata tctaaaattt ctccaatacc aaaacatgtg tttgaaggag
    24781 aatcaaatat agctaagtca gaaaaaaata ataatccagt tggttctggt gcattcaagt
    24841 ttaaggaatg gaaaaaaggt gaaagcatag tatttgaaaa gaatgcagat tattttggtg
    24901 gagaacctaa ggcagattct atagcgctaa aaataattcc taatgaagca tctcaagaag
    24961 cagctttaaa taatggcgaa atttcactta tgaagacatc tgctgaagga tatgaaaagg
    25021 caaaatcaaa ctcaaactta caaacttata cttatagtga agaaagatta aactacattg
    25081 tatttaacca aaatatatca aacatggcta acaaagaagt aagacaagcc ttatcatatg
    25141 ccttaaatag aaatgaaatg atagaatcag catatggaaa agaaggttct gtacctgcta
    25201 aatctatatt agttccagaa gcagacttct atacagaaga aggtgttgaa ggatatgacc
    25261 aagatacaaa taaggctaaa gacttattgg ataaaagtgg tgttaaaatt gataaattaa
    25321 aaataggtta taacacaggt agatttgggc ataaaaacta tgccttagta gctcaacaag
    25381 agttgaaaaa aattggtata gaagctgaaa tagttcctta tgaaagtaag gcattcttca
    25441 atatactatt tagtaatagc actgaatgtg atatgtatgt aaatggttat gcttggggat
    25501 tagaaccaaa cccatataga ggtatgtttg aaactggtca atattgcaac caaactaaat
    25561 attctaatgc tgaaatagat gctttatggg aaaaaggatt tactgagtta aacaaggaaa
    25621 aacgtgaaga aatatataag caaatacaac aggatatatc taaggatgcg cctatttaca
    25681 ctatagatta tgaacaaaat ttaatggcag ctcaaaaaaa tctaaaagga ataaaagatg
    25741 ctaaaccatc tcctgcaata ttatttgaag attggtctaa actgtatgta gaataattga
    25801 tgtaaaattt tatattatta attagaaaag gagatgtcta aaaataatat tgttttatta
    25861 ttttaaaacg agacatctct tttaattagg agaatttact tatgttaaaa ttaatattga
    25921 atagagtaaa agttttaata cctatgttaa tcttaatatc tatattatca tttggacttt
    25981 tagaattagc tcctggtgac ccagcagatg catatataaa tcctttaatg tcttcacagg
    26041 atattgaaaa tataagggtt aatatggggc ttgataaacc agtatatata agatatttaa
    26101 actggttgaa aaacacttta agtggaaact taggtatttc ttatataaac catatgcccg
    26161 ttacagaaca aattatggaa aaaatgggaa atacatttat tcttatgggt acttctttga
    26221 tattttcaat attggtagct atacctcttg gaatattttt agctgtaaat aaaaattcaa
    26281 taactagtaa agtatcatct gtttttaatt atataggtgt ttctatacct tctttttgga
    26341 taggtatgat actcatttca attttttcag ttaaacttaa cattttccca tcaggaggta
    26401 tgcatactat tggaaatgat agtattggag acttagtaaa acatttagtt ttgcctgtaa
    26461 taactttagg tctatataat actgctattt ttacaaatta tgtagaagct agtgtaaatg
    26521 aacaattaaa aaaacaatat gttattacag caagagcaaa aggattatca gaaaaagtca
    26581 tactatttaa acatgtcttg aaaaattcac tgacatcatt ggttacaatc ctaggcatga
    26641 gtatacaaaa attagtcact ggtgcatttg ttacagaagt agttttctct tggccaggta
    26701 tgggaagatt aatgattgat tcaatttttt caagagatta tactgtaatt atggcaataa
    26761 ctatgttatc agcactattt ttaattttag gtaatttagt tgctgatata ctatacttat
    26821 taattgaccc taaaataaaa tctagcaaag gaggattcta gttgtgttta caagtatctt
    26881 aaaaaaatta aaaaaagata aatcctttgc ttttgcatgt attactctta gcataataat
    26941 catattaatt atagcttctt ttatattaaa tatagactct aatgcaattg atactacttc
    27001 taaacttcaa gaacctagct taaagcatat ctttggtaca gacgaacttg gtagagatta
    27061 cttctctaga gctctttatg gtggaaggat ttcacttagt gttggtattt tatcaatgct
    27121 tatttctgta gtatttggta ctgctgtagg tgttattagt ggatatattg gaggtaagct
    27181 agaccaattc ttgatgagat taatagatat gcttatgagt ataccaagtt tcttagtttt
    27241 gattgtatta aatacttatc taacacctaa agtttccact attatactaa ttattggatt
    27301 cttaagttgg atggaagttt caagaattgt acgtggcgaa acattaaaaa taaaggaaaa
    27361 tgaatactgt ctagctgcta aagctactgg tatcaagact agaaatatac tattaagaca
    27421 tatagtttta aacttaaaag agactattgt agttgctggt tcgttaaata ttgctaatgc
    27481 tatcttaact gaatctgctc ttagtttttt aggtcttgga atccaattgc ctcttgcatc
    27541 atggggtaat atgcttcaag atgctcaaag acatattttt gacaagttat atttagctgt
    27601 atttccagga ttacttatat ttttaacagt catgagtttg actataataa gcaaaaaatt
    27661 ttctagtaat acttaacaaa ttttatatag aaaataaaaa cagtgattat ctaaagatat
    27721 acactgtttt tatttttcgt ttaaaaaaat acatattttg tatattataa ctttaaatac
    27781 tactctacca tgttatgtaa aacctattat tgctctcaaa catatagatg aaaaactaat
    27841 agtttattat aataaaaatt gatttattta tttgttattt taataacatt tttaagagtt
    27901 ctttttacta aagaaatcta taataaattt aaatacatgt tggtctacat ggctataacg
    27961 ttctttttta ggtctacata atataacttt ccatgtaata ggatgattaa aaggcttttc
    28021 tataattttg ctattttcaa aaaaatcatg aactggtgat ggtagaattg ttataaaatc
    28081 agaatttgtg gttgatagca acaaaaaatc ccatgaacca gacattatat atctttttaa
    28141 cttaacattt tcatcagtaa atttttgcat tagcttatga tgtatcataa aagtaggatt
    28201 aaatattgca agtaactgct cattcaaatc gttccaatct atcttatcct tcttagcaag
    28261 tggatgattt atatttaaaa atgctgtaag ttcatcttct tgaagcacat gttcagttac
    28321 tacactttta tcaattttat gtggatgtaa caatactgca taatctaatt cctgtaagat
    28381 aagcattcta tttaagtcat atgcaccctt ctctactata tcaaattcta tatctggatt
    28441 atttgcaact aactgtgcaa ctacatctga aaatgctatt ccaagtataa gtggaggtat
    28501 tcctattcta acttttcctt taaattgaac tgaatcttct cttaaatctt ccatcatatt
    28561 tttgtattca tttatgatat gttctgcatt tacataaaat ctttctcctg ctggtgttaa
    28621 cccatttaac ctgcctttat acctttcaaa taaatataca tcttcacttt cttcaaaatt
    28681 ttttataatt tgacttaatg ctggttgaga tatgtgaagt gtcttagatg ctattgataa
    28741 attaaaacca gatttcacta tttcaacaaa atatttcaac tgttttatat ccattttaaa
    28801 cccccttccc caaaagtata atttagatta tattttttct tctaatgata ttttatagga
    28861 aaatcaacat aatttcatta atattttaac aaaatatttt tctaaatcta ctataaattt
    28921 ttatcctata aatttttctt atacactata taaaaaatta gacttagaca aaacgctttt
    28981 ttcgccgtaa tctataatta gaaacaggaa aacctaaagc attaggaata aaagtaattg
    29041 aaatacttaa aaacaagctt gtattaaaaa agtactttat tatagtgttt cctaatttct
    29101 ttattcagaa aatttttaat tatcattcaa gaaaggtaac tattagatat gaaagatgta
    29161 gtaatcgtat cagcagtcag aacacctata ggaagttttg gaggtgtatt taaaaatact
    29221 tcagctgttc aacttggaac tatcactgtt aaagaagcga tatcacgtgt aggacttaat
    29281 ttatctgaaa tagatgaagt aataattgga aatgttcttc aaacagggct tggacagaat
    29341 gttgctagac aaattgctat aaatgcaggt ataccaaatt ctgttccaag ctacacagta
    29401 aataaattat gtggttcagg gcttaaaagt gtccagctag ctgcccaatc aatcacatct
    29461 ggtgaaaatg atgtggtaat tgcaggtggt actgaaaata tgagccaagc tccttatatc
    29521 gttccaactg ctcgctttgg tagtaaaatg ggtgacataa ccatggtaga tagtatgcta
    29581 acagatggcc ttattgatgc tttcaatcag tatcatatgg gaataactgc agaaaatatt
    29641 gcaactaaat ttgaatttac tagagaaatg caagataaat tggcattaga aagtcaaagt
    29701 aaggctgaga atgctataaa aaacaaccgc tttaaagaag aaatcgttcc agtagatgtt
    29761 ttaatacgtc gaggaaaaat agaaactatt gataaagatg aatatcctaa attaggtatg
    29821 acatttgaag gtttagctaa acttaaacct gcattcaaaa aagatggtac tgtaacagct
    29881 ggaaatgcct caggtattaa tgatggtgcg gctatgttaa tactaatgag ccaacaaaaa
    29941 gcagacgaac taggtattag accacttgct aaaataaaat cctatgcttc agctggtgtt
    30001 gaacctgaag tcatgggtac tggtccaatc cctgcaacta gaaaagcact gaaaaaagct
    30061 ggacttagca tcaatgatat agacttaata gaagcaaatg aagcgtttgc tgcccaagca
    30121 ttagctgtta aaaatgaact tcaaatagat tcatcaaagt taaatgttaa tggtggtgca
    30181 atagcattag gacatccaat aggagcaagt ggagctagaa tacttgttac cttaatttat
    30241 gaaatgcaaa aacgtaaagt tgaaactgga cttgcaacac tttgtattgg tggtggtcaa
    30301 ggaatatcaa tggtggtttc acgataggag gaaatatgaa taaaatagtt agcattgatg
    30361 aagctctatc tcatgtaaaa gatggagata caataatggt tggtggattc atggccaatg
    30421 gttcaccaga aaatttaatt gattatttat gtagtaaaaa tataaaagat ttgacactaa
    30481 tttgcaatga tactggcttt attgacaaag gagttggcaa aatggttgta aataagcaat
    30541 ttaaaaagat aattgcttct catgtaggat taaataaaga aactggaaga caaatgaata
    30601 acaatgaaac agatgttgag ttagttcctc agggaactct tgctgaacaa atacgtgcag
    30661 ctggttatgg tctaggaggt atactcacac cgactggtat tggtactctt gttgaggagg
    30721 gaaagcaaaa aattgttgtc gatagcaaag aataccttct tgaaaaacca atttatgcag
    30781 atgttgctct tctatttgca tcaaaggtcg ataaagcagg taatctagtt tataaaggct
    30841 ctatgaacaa ttttaataat ttaatggcat ctgctgccaa aattacaata gttgaagcag
    30901 atgaaatcgt tgaaattggt gatattgacc caaatgaagt taatacacca ggtatttttg
    30961 tgaattacat cattgaagga ggtaatttat aatggataaa ttagaaatgc aagaatatat
    31021 tgcaaataga gtatctaaag aattaaaaga cggagccgtt gtaaaccttg gaataggtct
    31081 accaaccaaa gtagcaaatt atattccgga taatgtaaac gttatcttac aatctgaaaa
    31141 tggcttttta ggtttaggtt cagccgaaga tggaaattca agtgatgaaa ctattgtaaa
    31201 tgcaggtggt caaccagtta ctatacttcc tggaggatgt ttctttgata gtgctacttc
    31261 ttttggaata atcagaggag gtcatgttga tataactgtt cttggcgcac ttcaggttga
    31321 caaatatggt aatatagcaa actatatgat tccaggtaag atggttccag gtatgggtgg
    31381 agctatggac ctagtaactg gagctaaaaa agttattgta gcaatggaac atacttcaaa
    31441 aggttctgca aaaatattaa ataattgtac tcttccactt actgcaacaa atgctgtaga
    31501 tttgatagtt actgaaatgg gagttatgga agtaacatca gatggaattt tacttaaaga
    31561 aataaatcca gctttcacat tagatgatgt tatttctgct actgaggctc ctttaatatt
    31621 gtcagattca ttaaatggaa aaatatctgt tgtttaaaat aattaaaact agaaaataaa
    31681 aatctcttag acgtattaca tataaatttg tattgcttaa aatattaata taaaaataaa
    31741 ataaaattgg aggaaatgaa aatggttaaa gataaagttg tattcgtaac aggagctgca
    31801 agtggaatag gtaaacaaat agctgaatcg ttcttaaaaa atggtgctaa agtaatgttc
    31861 tctgatataa atcaagaagc tttaaataat accataacag agttacaaaa aaaaggttat
    31921 gattgcatga gtgtaaagtg tgatgtaact aaggaagaag aaattaacca cgctatagac
    31981 aaaactgttg aaaagtatgg cagattagat atattaataa acaatgctgg acttcaacat
    32041 gtttctatga tagaagattt cccaactgat aaatttgaat ttatgataaa aataatgctg
    32101 acagcacctt ttatagctac taaaaaagca tttcctataa tgaaaaaaca aggctttggt
    32161 cgtataataa atatggcctc aatcaatggt gtaataggat ttgctggaaa ggctgcttat
    32221 aactcagcaa aacatggact tattggacta acaaaagttg ctgctcttga agctgccgat
    32281 tctggtataa cagttaatgc tttatgccct ggatatgtag atactccact tgtcagaggt
    32341 cagttcaatg acctttcaaa aactcgtaat ataccattgg aaaatgtctt agaggaagtt
    32401 ttatacccac ttgtaccaca aaaacgccta ttagatgttc aagaaattgc cgactatgct
    32461 atgttcttag caagtgataa tgctaagggt attacaggac aagcttgctt actagatgga
    32521 ggatatactg cacaatagtt attatattta gggcttgaag aaagtattct tcaggtcctt
    32581 ctactaagga gggatattta tgagtattat cgcaccaatt ggtataatta ttggtatcat
    32641 agctattata tatttttcag ttaaagaaat tcatataact atagctgctc caatagcaac
    32701 tttaatagtt gttattttaa ataaaatgga tgttgtaaca tcaatgctag gtgctgacaa
    32761 aaacaattat atgggtgcac ttggaaacta tataatgagt tattttgcaa tattcttatt
    32821 aggctcaata cttgctaaat ttatggaaga aagtggagct actgtatcaa tagctgattt
    32881 tattttaaat aaatttggct ctaatcatcc ttatagagtt ttagttgcta tatttatagt
    32941 aagttttata ttaacgtatg gtggtataag cttatttgta gttatgtttg cggtcattcc
    33001 acttgcaaga actctattta aaaaacttga tatttcttgg aaccttattc agataccact
    33061 ttggcttggt attgcaacaa ttactatgac tataattcct ggaacaccag ccattcaaaa
    33121 tgttatacct attcaatatc taaatacgtc tcttactgca gctactatac caagtattgt
    33181 aggtagtata ggttgtgcta cgtttggact tgtctatatg aaatatgctc taaacaaaag
    33241 tattagaaaa ggtgaaactt atgcaactta tacttcagaa ttagaagaag aatctttaga
    33301 tagagaatta ccaggatttt ttgcaagtat ttttcctcta ttagcactcg taattatagc
    33361 tataactgga agtacttttg gttcagaatt tatgaaaaaa aatgtaattt acatagcttt
    33421 aatagttgca attcttttat ctgctttttt attccataaa tttctatcat ctaagataca
    33481 gacattgagc ataggtgcta gtggttctat aggtcctata tttgctacat cttctgcagt
    33541 tgcatttgga gcagtaataa tggctgcacc tggttttgat gtatttagca aacttataat
    33601 gtcaatacca ggtagtccac ttataagtct tactgttttg acttcaacaa tgtcagcaat
    33661 aacagggtcc tcttctggtg cattaggaat agtaatgcca aactttgcag attattattt
    33721 aagtactggt ctaaatccag aattaattca ccgtgttgct acaatagctt caaatatact
    33781 aactatagtt ccacaaagtg gtgtttttct tacattctta agcttatcta agttaacaca
    33841 taaaactgga tttaaagaaa ctttcattgt agttgcagtt ggttcactaa tagcagaaat
    33901 tattgtaatt acattaggat tactaatgta ttaatataaa acaaattaaa attcataata
    33961 tgaaaggtgg tgtctcaaag tgaacttttt acttaatgag acactctttt tatatgaaat
    34021 aacatatgcc tatcatttaa acaataaaaa aggccttatc tctattttga gacagaccct
    34081 ttttatttct taaagattta aataattata atttgttgct aatacgaaag catctactga
    34141 ataaatttaa ccaaataaaa aaaaatttat cataactata aatttacgtt atggaattat
    34201 tataaaaata ttattttctc taactaagta attccatact atacaggctt ttaatacaaa
    34261 ttgtcaaaca cactgaaata tacctattta ttccatatat atctttttta catatcttta
    34321 cagtaaaaaa agtcttaatc ttatgttagt atagattcac gggtaacccc ctacactaaa
    34381 ggttacaaat cagtaacatt tttagaattt ttagattaag aggtgtttaa tgatgagaag
    34441 aaatatacca acaaaattaa aaactatatt agctttagga gtgttaactt tagcaacagc
    34501 ttcaagtgct gttactgcaa gtgcttcatc acttgaaaat aatgtaaata taagtaacaa
    34561 aagtttagta tatagtaata ctaaatacaa gttttctgca aaaccaaatt gttctgtaaa
    34621 accagaactt aagcctgata aagataactc ttgtaaggat aagaatcata atgacaagaa
    34681 ttgcaacaac actaataaac ctgaggacaa caataattca gactctacta ataagcctgg
    34741 taacaataaa cctgagtcta ataaacctga agacaacaat aattcaggct ctactaataa
    34801 acctgataat aataaacctg agtctaataa acctgaagac aacaataatt caggctctac
    34861 tgataaacct gaagacaaca ataattcaga ctctactaac aaacctgatg ataataacaa
    34921 ctcaggctct acaagtgaaa gtttttcagc ttaccaaaaa gaagttgttg acttagtaaa
    34981 tatagaaaga gctaaagctg gattaaatcc tcttactctt gattcttcta tatcaaatgt
    35041 tgctacaaaa aaatctcaag atatgattga taacaactat ttttcacaca attctccaac
    35101 ttatggttct ccatttgaca tgttgaaaaa atttggaata agctataaga cagcaggtga
    35161 aaatatagct atgggtcaaa aaactcctaa agaagttgta aatgcatgga tgaattctga
    35221 aggtcacaga aaaaatataa tgaatccaaa tttcagtaaa ataggtgttg gagtagcaca
    35281 aaaaagtggt ggttcaattt attggacaca aatctttgta ggataaaata atctttttcc
    35341 atacatatca aaagattatc tctaagtgat aaaaaacaca aatgagatac tcttttgtat
    35401 ctattttaaa attatcaaat ccaaatatac atactataaa tattatttgt tctcttaatt
    35461 ttagtgtgta gagcaatata taaaaagtat tggcaagatg aaaatggaaa acttaaaaag
    35521 atatttaata ggtaaaaaca ggatcttaat atcttcataa aaaaaggctg tctcaaaata
    35581 gagataaggc ctttttcatt gttgaaatga ttaaaatata tttgatttca tacaaaaaga
    35641 gtgcctcatg aactaaaaag ctcactttga gacactctct tttatcaatt ctatataagc
    35701 attataatac tttaatatta ttcagctaat tttttgtatc cttcatatct ttctttagca
    35761 tcagcttcag ctttagcaaa taatccatca gcttcctctg ggaattgttt agctatagca
    35821 gaatatctta cttgtgcaag tatgaaatct ttgaagcttg cagttggttc ttttgaatct
    35881 aaagtgaatg ggtttttacc ttcagctttt acttctggat tgaatctgta taaatgccag
    35941 tatccgcaag caacagcttg tgcttcgtta gctacagttc ttcccatacc ttcttttaat
    36001 ccatggttta tacatggagc ataagctatt attaaagatg gcccatcatg tttttcagct
    36061 tctataacgg ctttgataaa ttggttttta tcagcaccca tagcaacttg agctacatat
    36121 acgtttccat atgtcatagc catcattcct aaatctttct ttctagattt tttacctgaa
    36181 gcagcaaact tagccatagc agcagctgga gtagctttag aagcttgacc tcctgtattt
    36241 gaatatactt ctgtatcaaa tacaagtacg tttacatctt caccagatgc aagaacatgg
    36301 tctaatccac cgtaaccgat atcatatgcc caaccgtctc cacctagtat ccattgagat
    36361 ctcttaacta gataatcttt tctatctttt atagctttta ctaactcttt agctttttca
    36421 tctgtacaat cacaagctgg tttttctaat aattcaacaa ccttagcact tgctacttta
    36481 gaagcttctc catcatttct agaatctaac cactctgtaa ataccgcttt agcatcttca
    36541 cagatatcca tagaaactaa ctctgtcata gcatctacta ttttatttct tatttgctta
    36601 acagctgtgt acataccaaa tccatattca gcattatcct cgaataaaga gtttgcccaa
    36661 gatggacctt taccttcatg gttacaagta taaggaattg atggtgcaga agctccccat
    36721 atagaagaac atccagtagc attagctatc atcattctat ctccatataa ttgtgtaact
    36781 actttaatgt atgcagtttc tccacatcca gcacatgctc ctgaaaactc cattaatggt
    36841 tgtctaaatt gacttccttt aacagtgttt gcaggcataa catcaccttt tggagctacc
    36901 tcatcaggat ttactgcaaa tgcccaatta tctaactctg tatcaagttg agtatctatt
    36961 ggcttcataa ctaaagcttt ttctttagct ggacatatgt cagcacagtt tccacatcct
    37021 gtacagtcaa gtggactaag ttgcattcta tattttaatc cttctaatcc tttacctaat
    37081 gcttttttag cttcaaatcc ttctggagca ttagctaatt cttcttcagt aactaatact
    37141 ggtcttatac atgaatgagg acatataaaa gaacattggt tacattgaat acagttatct
    37201 attatccatt caggaacatc aacagctata ccacgttttt cataagctgc agtaccacaa
    37261 gggaatgttc catcttctat accattgaat gtacttactg gtaagttgtt tccttcttgt
    37321 gcagtcattg gtcttagtat attttttata aattctggtt ctttaacttc tcctttatct
    37381 gcatcaacag cattttccca agaagctgga acttcaactt taactaaagc atttattcct
    37441 gcatcaacag cagcatagtt catgttaact attttttcac cttttttacc ataagcttta
    37501 actatagaat cttttaagta tttaacagca tcttcttctg gtattatttc agctaattta
    37561 aagaatgcag attgcattat catgtttatt ctgtttccaa gacctatttc ttgtcctagt
    37621 ttaacagcgt taactgtata gaattttata tcatttttag ctatatattg tttcatatga
    37681 gctggtaaat gttcttcaag tcctgcttgg tcccatatag tgttaagtac aaatgtacca
    37741 ccttttttaa gaccttttaa taaatcatat tgataaacat atgattgttt atgacaggca
    37801 atataatcag cttcatctat taaataagta gctcttattg gagtatcacc aaatcttaag
    37861 tgagacatag ttataccacc agatttttta gagtcataat caaagtaagc ttgagcatat
    37921 ttttcagtat ggtcaccgat tattttgata gcttgtttat tagctccaac agtaccgtca
    37981 gaacctaatc cccagaactt acatcttata gttcctttag aagctatttt tattggctca
    38041 gatggagtta aagaagtatt agttacatca tcaactatac ctactgtaaa tccattttta
    38101 ggttgttctg aaactaagtt atcaaaaaca gtttttatat ctgaaggagt agtatctttt
    38161 gaacctaatc cgtatcttcc acctattatc ataggagcat tttcttttcc atagaataca
    38221 tcacgtacat ctaagtataa tggttcacca gttgaacctg gctctttagt tctatcaagt
    38281 acacatattc tttcaacagt agatggcata gcatctaaga aatgtttcat tgagaatggt
    38341 ctatataaat gaactttaac taaaccatat ttttctccct tagcatttaa gtaatctata
    38401 gtttcttcta ttgtttctgt tactgaaccc atagctatta atacgtattt agcatcttct
    38461 gctccatagt aatcaaataa actatgtttt ctacctgtta aattactcat tttttccatg
    38521 tatttttcaa ctatacctac tatattttga tagtatttat tagaagcttc tctagtttgg
    38581 aaatatatat ctgggttttg agcagtacca cgagcaactg gatgatttgg agataaagca
    38641 ttatctctaa atgcttgaac tgcttcaaag tttaataaac ttgcataatc ttcattttct
    38701 agtaattcaa ctttttggat ttcatgtgaa gttctgaatc catcaaagaa atgtataaat
    38761 ggtaatctac cttctattgc agctaaatgt gcaacaggtg ctatatcagc tacttcttga
    38821 actgaaccag aagctaataa tacacatcca gtttgtctag cagccataac gtcttggtga
    38881 tccccaaata ttgataaagc ttgagatgct aaagcacgag cacttacatg gaatactcct
    38941 ggtaacaact ctcctgcaac tttatacatg ttaggtatca ttaataataa accttgagat
    39001 gctgtaaaag tagaagttaa agctcctcct tgtaaagaac cgtggaatgt tcctgatgca
    39061 cctgcttctg actgcatttc aacaacatta actgtttgtc caaatatatt ttttcttcct
    39121 tgtgatgccc actcatcaac tacttcagcc atagttgaag atggtgtgat tggatatata
    39181 gctgctacat ctgtaaacgc ataggcaaca tgagctgcag ctgtatttcc atcaagtgtt
    39241 ttcataaact tagccataat atgtatcctc cttgatagct acaattgtac ttgtttataa
    39301 caagtctatt tttttatatt tacatataat ttacacaaca aaactataaa cacacatata
    39361 gtcgcgcaaa tactctatct tctaatataa tactacagat tagataaaat tcctttgaaa
    39421 attgtaaatt aattacatat ttaagtagat tttttttaaa attaaatatg ttaagttttt
    39481 ttcataattt tgtatacaat atataataaa ttaagttaga tttttca
//
LOCUS       DAEPHU010000034        38852 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 01A10CD0081
            SAMN05941466-rid12468953.denovo.034, whole genome shotgun sequence.
ACCESSION   DAEPHU010000034 DAEPHU010000000
VERSION     DAEPHU010000034.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941466
            Sequence Read Archive: SRR6291087
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 38852)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 38852)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068158.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 22:43:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,892
            CDSs (total)                      :: 3,805
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 87
            rRNAs                             :: 8, 1, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 55
            CDSs (without protein)            :: 55
            Pseudo Genes (ambiguous residues) :: 0 of 55
            Pseudo Genes (frameshifted)       :: 21 of 55
            Pseudo Genes (incomplete)         :: 28 of 55
            Pseudo Genes (internal stop)      :: 16 of 55
            Pseudo Genes (multiple problems)  :: 8 of 55
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..38852
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941466-rid12468953.denovo.034"
                     /strain="01A10CD0081"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            25..507
                     /locus_tag="KR231_001861"
     CDS             25..507
                     /locus_tag="KR231_001861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HBH0004238.1"
                     /translation="MYNNIKNILKENHITFEEYDHEPILSFEKAKEIREKLQYTGVES
                     KSLFIKDRSGNYYIFVTTEGKKLDPKTIKNVLGGKVSICSKEELTQKTQCLPGCVSPF
                     GYEKNISLVIDQDIFNHDKIIFSPGIPEKTFIITASGFKKVINNINNTTYKYIYINEF
                     "
     gene            complement(1206..2360)
                     /gene="nagA"
                     /locus_tag="KR231_001862"
     CDS             complement(1206..2360)
                     /gene="nagA"
                     /locus_tag="KR231_001862"
                     /EC_number="3.5.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898693.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylglucosamine-6-phosphate deacetylase"
                     /protein_id="HBH0004239.1"
                     /translation="MKSFIYADKFFMKHGIKEKGYLSIINGKFGEFQQERPNVTDNVI
                     DFSGKYIAPGLVDTHIHGLLGADVMDNTFEAINTISKGLLKYGVTSFLPTTLTDSVDT
                     LSDSVENISNSFNRVEGAKIQGIYLEGPFFTEKYKGAQNEKYFKDPDINILKLWQKKS
                     KNLIRKIAIAPERKGSIELTRYATKNNISVSLGHSSATFEQVKQVVNSGAKVFVHTYN
                     GMSPLNHREPGMVGAAMVLKDTYAELICDGHHVSPIAVKIMMDAKSSNNIALITDCMR
                     AGAMEDGKYTLGKFNVNVKNSVARLNSGSLAGSVLTMDKAVRNIVDWNIATLEDAIKM
                     ATYIPALSCNIDNVCGSIHQGMEADFIVTDKDFNIYETYISGICKYKVNK"
     gene            complement(2443..3168)
                     /locus_tag="KR231_001863"
     CDS             complement(2443..3168)
                     /locus_tag="KR231_001863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBH0004240.1"
                     /translation="MIKRNDKRPIYDQLVEILRTKIENEMEPNDRMLSERKICDEYGV
                     SRTTVRLAMAELEHMGYIYKRHGKGTFVAALSQNSQNLMESYSFTDYMRTQGKKPGTK
                     VLSFEVVESTKYFSEKLGITPGEKMIKIMRLRLADDLPMMLERTYLPMKEFIGLTKEK
                     IEQKPLYEIFREDYGEIIKVADEEFSAGIISDKEAKLLEVPGDSPCLKLLRTTYNDDN
                     IVIEFTLSVARSDKFVYRVRHVR"
     gene            3435..4364
                     /gene="pfkB"
                     /locus_tag="KR231_001864"
     CDS             3435..4364
                     /gene="pfkB"
                     /locus_tag="KR231_001864"
                     /EC_number="2.7.1.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-phosphofructokinase"
                     /protein_id="HBH0004241.1"
                     /translation="MITVITFNPSIDRMYRVNNINIGEVQRVVSKNATAGGKGLNVSK
                     VCKILKENPLAMGFLGGFNGEFIKNELRKLDIQNKFTKIEQETRNCLNIIEDNKVSTE
                     FLEKGPIVEKSDLERFENDIEEVLKNTKILVASGSYCENMPIDYYEKIGNICRANNIK
                     FILDTSGEALKIALKSKPYLIKPNIDEIRHLLGINIESREEIILSGKKLIEMGAENVC
                     ISLGKDGMVYLNEDNVYYVKVPVVKCINTVGSGDSTVAGFSVGILRGYKIENLLKFAN
                     ACGISNALNMETGFVDLGEIDKYQDLVEVKKLS"
     gene            complement(4493..5410)
                     /locus_tag="KR231_001865"
     CDS             complement(4493..5410)
                     /locus_tag="KR231_001865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HBH0004242.1"
                     /translation="MKNIKMGMIGLGSIAQKAYLPILTKSERFEFVGAFTPNKVKREK
                     VCSDYRIMQFDSIESLAKKCDCIFLHSSTETHYEIIKILLNLGVHVYVDKPLASTVSQ
                     GEELIELSTKKNLNLMVGFNRRFCPMYKEIKNNATEIVSINICKHGLNSLRNVKFDST
                     LIDDYIHVIDTALWLANEDVEISGEDLFLTDNKNLIFVSHKLKGKNFSINTSMHRDSG
                     TKLEQVEILSKGKIQRVKNLNVLEIEEGGNLTLKQSGAWVNILKQKGFEDISNHFIDC
                     IENNIKPAISGEECIKAQRLLEKIINSVK"
     gene            5880..7049
                     /locus_tag="KR231_001866"
     CDS             5880..7049
                     /locus_tag="KR231_001866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HBH0004243.1"
                     /translation="MKMFKLEEQKLKDLGAIITTNEIKQQPELWLETYEIYKSNKEKL
                     SRFIDTISNNHGQFRVIFTGAGTSAYIGNSILPYLKNKNDIRKYIFEAIPTTDIVSNP
                     YDYLKKDIPTLLISFARSGNSPESLAALNLGNKIVDNFYHLAITCNPEGELAKMTKND
                     ENNYLLLMPSKSNDEGFAMTGSFSCMMLSAMLIFDSLEDDVEKSYINAIVEMGRNVID
                     RKDEIHELINKDFDRVVYLGSGGLGGLTQEAQLKLLELTAGKISTVYDSPMGFRHGPK
                     SFIDENTLVFEFVSNCLYTRKYDLDVLEEIKRDKIAKFTCAVSVENENNFSGTKFEFK
                     EKYNKLPDVYLAMPYILFAQTIALFVSVKVGNKPDTPSATGTVNRVVKGVTIYEY"
     gene            7098..7949
                     /gene="gatY"
                     /locus_tag="KR231_001867"
     CDS             7098..7949
                     /gene="gatY"
                     /locus_tag="KR231_001867"
                     /EC_number="4.1.2.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-bisphosphate aldolase subunit GatY"
                     /protein_id="HBH0004244.1"
                     /translation="MALVTTTSMLKKAQDEGYAVGAFNVENMEMVIAVIEAAEELNSP
                     VILQTTPSTVKYAGLDYYLANAKVAAERVKIPVAMHLDHGSSFDLAMKALRSGYTSIM
                     IDGSHESFENNISISKSVVKACSPSLIPVEAELGKVGGKEDDLDGGNSNDYTNPKEAK
                     EFVDRTGISSLAIAIGTAHGLYKGEPKIDLDRLSEIKNVVSIPLVLHGGSGIHDDIIK
                     EAIKRGIAKVNYATELRIAYSKGVKKVLDEDSEVIDPKKYGLAGLQSVKDFVKEKIKV
                     CGSVNRV"
     gene            8275..10176
                     /locus_tag="KR231_001868"
     CDS             8275..10176
                     /locus_tag="KR231_001868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HBH0004245.1"
                     /translation="MRERIILETLKNSSGYLNIDYFADKLGVSTRTIRNEIKKIETIK
                     ECNGFKLEYKSKLGYILNIKDQDKFEHYLRNLPSDLVENPEQRLESIIVELLVNEGYK
                     TIEQLSKKFLVSSSQIKNDLKKIDEKIKDTELKLERKAHYGIKIEGSIKEIQSILVDS
                     YFRGNRNITEYRNKFIDNLKLANIRSTIKNVLNEHDLEANLTELEEILAQIIILYIRV
                     SMRVAGNASDLKLYTEDLIIDKLLDKIFRDKKYNLNYDEKYYLKELIKLKTKDKKATI
                     KNIDKNKLQDIMFEFFREIDKKYNSNFLEDKEFFNLFYLHIACLIERIKKNHKIINPF
                     SVKISQQYPTVFNLSIQFSKIIENEYHIKISQDEIGFIATHIAVPFEKREEANFNKKY
                     KIAIICSSGGGSAFLINLRLKEIFPNAEIRNFSLLEEKAVIEFAPDLIFSITNLLFEI
                     NAPVILINEILDELDYLDIKESVRFADHIGNISSPKQYILGLFDKNHFRCIKDKAKYK
                     DILDSMSKCIVDEGACSPTYPKDVWERESYLSTIYTNGVAIPHPIEMTGNKNIISVAL
                     IQTDIIYENRVPKIIFMISLIKGNLELHKQISKYLSKIMANKDMVDMLNKSQSYEEFM
                     YKLKIYLGG"
     gene            10179..11222
                     /gene="ypdE"
                     /locus_tag="KR231_001869"
     CDS             10179..11222
                     /gene="ypdE"
                     /locus_tag="KR231_001869"
                     /EC_number="3.4.11.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase"
                     /protein_id="HBH0004246.1"
                     /translation="MNIEFFKRLSEADGIASNEEEVRHVLLEELKAYSDKIICDGLGS
                     IIFSKIKDESAPNVMICAHMDEVGFMVRSIDKLGMIHLITIGGVKPLAQFVQKVRITT
                     KEGKKIPAVINATYNNGKAENIYADIGAYTEEDVYNLGINVGDMVTYTTSFEEFTLPD
                     RLVGKAFDDRIGCFVMGEVLKELRKENLNCNIHFAATSSEEVGIRGAKTSTQLINPDI
                     VFVIDVACAKNEFVRDYTNQKQIDKGVMLMHRDRTLVPSRKMIDYVMEIADKNNIPLQ
                     HDMFESGGTDGGEAHLVNEGKPCVVTCVPVRYGHCAFSIVSNKDLENIIRLYTQLILN
                     FDEEQYKHIRNFI"
     gene            11237..11542
                     /locus_tag="KR231_001870"
     CDS             11237..11542
                     /locus_tag="KR231_001870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HBH0004247.1"
                     /translation="MSTEVQIMELISTAGESKSKAFEALKKVKSKDFKGAKLLIEEAR
                     KIDIEAHRIQTELITQDLNEDVESPAMSLLMVHAQDHYMTSQLAKDLIEALIYCLDK"
     gene            11639..11974
                     /locus_tag="KR231_001871"
     CDS             11639..11974
                     /locus_tag="KR231_001871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBH0004248.1"
                     /translation="MKILLCCAGGFSTNMLMQNMKKVVKESAKLNEKDFEFTAIPADS
                     IESEVDDWDIVLIGPQIAHKIDFLKGILEPKNKPFAVIDKDVYGKMDGATVMKLALIT
                     YKKHQLAQG"
     gene            12006..13328
                     /locus_tag="KR231_001872"
     CDS             12006..13328
                     /locus_tag="KR231_001872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBH0004249.1"
                     /translation="MFSKFEAFMNRVFMPLAHKVDNQRHLGSIKAGMVAMTPFTILGS
                     IFAILPALPNMLGENNPISKFILNNSAILDLPVSLSIGLIGLYACMCIAFNLGNYYKL
                     YIPGCVALSTFSFLFLVASFTPDGALEIGNLGAKGLFTGMIAGLGSVELYNFCNKKNI
                     TIKMPENVPDFVSRSFELIPTTIIVCGTFIVARFISLKVFGELPPQILTQFLSPLVGS
                     MDNPWSVLALNFAICTIFFFGIHSSVFSPITRPIMITFIAENIAAMQAGETIPHFFTA
                     GASSAFFGFTGCGISIGCVIACMLSKNASYKKIGRVSLFPALFGINEPILFGAPIILN
                     PIMFIPHVFGGAIIGTLPMFFMHWGWLAKPVFDPPYVGVFLEGFLTNGDWHSILANAL
                     QLVLAVLLYWPFFKIMERQQNNKKQKEETKNIFSKEEEDLLDDLGLDF"
     gene            13338..14408
                     /locus_tag="KR231_001873"
     CDS             13338..14408
                     /locus_tag="KR231_001873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HBH0004250.1"
                     /translation="MNNTMERLVSLIYKRGVDALLIKAKNTKRYIGALSGSGVYVLVT
                     KDKNYQILDGRYIDEADKKTTGFIKRIVSQGSYIPTIIELLKELNIKKLAIENQAMSI
                     QEYLSLKNEGFEINLITNELWKLRAIKSKEEIELIKKACEITDEVFDEVISEIKKDMT
                     ELEVSALIQYHALKKGASGMSFETIVVSGERGAMPHGRPTNKKLKVNEAITIDFGVVY
                     QGYQSDMTRTISIGKPPKIIKEIYDVVLEAQLSAIESIKEGTRASDVDKVARKIIDKH
                     GFGEYFNHGLGHGIGLGDGEVPTLNPNSEDILVEGMVMSCEPGIYIPNVGGVRIEDDI
                     VIIDGKGVPLNKTSKEFIILGE"
     gene            14413..15600
                     /locus_tag="KR231_001874"
     CDS             14413..15600
                     /locus_tag="KR231_001874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HBH0004251.1"
                     /translation="MKYNFNKVLNRKEGNCRKWSNHVIKEKFGLNEDAIPMDLADIDF
                     ECAPAIKESILKRASVGDYSYTFIGDDFYDAIINWNKRRFDVYIEKDWIKLTFGTVST
                     LHYIVQAYTKEGEGVLINTPAYDPFAEAVVNNNRKLCCSSLKLDNNRYYLDLEDMENQ
                     MKYENIRLLIFCSPQNPSGRIWTKEELYQVSELCLKYNVILVSDEIHRDIIFKDYRFV
                     SLWNAHPEIYKNSIICVSPNKGFNLGGLKTSYVLIRDVKIRETLLERLKSNSITSPNV
                     FAIPAIVAAYNESEEWLDAMTSYVEENFEIVYDFFETNIPKAKVMKSDSSFLAWIDVR
                     EVFRNEEESKEFFRHANLTMVVGSYFVKDGDGFIRINVGCPRETLNEALNRIKKTYIS
                     MYC"
     gene            complement(15797..16669)
                     /locus_tag="KR231_001875"
     CDS             complement(15797..16669)
                     /locus_tag="KR231_001875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldose 1-epimerase family protein"
                     /protein_id="HBH0004252.1"
                     /translation="MNILQNENLIIESSSFGAELTKIFSKKYDKNILWDGNKKYWGRQ
                     SPILFPIVGKLFDNETIIEENLYSMTQHGFARDMDFEIVDKGDTFVTYKLTDNESTLK
                     KYPYSFELIINYTLNDNSIEVEWIVKNTDSKDIFFSIGGHPAFNLPFYEQNDFSKHYL
                     EFKSKNDVEKINLNGSFTDDIIPIGKLKNLQLNPEVFKNDALIYTNIDEVSICNNDGS
                     KYVTISMEDFPLVGIWTPYYSETNSTAPFLCIEPWYGLADSINSNKIYKDKKFINKLS
                     KGKVFTASYNINIH"
     gene            complement(17063..17254)
                     /locus_tag="KR231_001876"
     CDS             complement(17063..17254)
                     /locus_tag="KR231_001876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0004253.1"
                     /translation="MDDFSKLKSLYEDGYRCIYHDCVDNNYTIYLKNFYTEGSETIEL
                     SSESDFSQFKDYIDGLRMS"
     gene            17474..18520
                     /gene="cobT"
                     /locus_tag="KR231_001877"
     CDS             17474..18520
                     /gene="cobT"
                     /locus_tag="KR231_001877"
                     /EC_number="2.4.2.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate-nucleotide--dimethylbenzimidazole
                     phosphoribosyltransferase"
                     /protein_id="HBH0004254.1"
                     /translation="MSLLESISKNIYSLDNSSIEKTKQRLDRLIHPTGSLGKIEDICM
                     QLAGIFGNENFDTSKKVIIAFAGDHGVYEEGVAPDPQNITKLQFPNFSKGLCGVGVIS
                     KFVGADVVAVDVGINCDEKLDGVLDYKIRKGTSNMAKGPAMSKQEAIRCLEIGIEIAE
                     QCIEKDYKVIGIGEMGIANTTPSTAIISVISGCDPLEVTGIGAGLKKERLKHKAEVIR
                     KAIEINNPNPTDGVDILSKVGGFEIGSMAGVILGCSANRIPVVIDGFISYAAALIAYK
                     INPKTREYMIASHLSAESGTKRALDILKLDPLLNMDMRLGEGSGAALAFDIIEASNYT
                     YKNMATFDEIDMGR"
     gene            18552..19112
                     /gene="cobU"
                     /locus_tag="KR231_001878"
     CDS             18552..19112
                     /gene="cobU"
                     /locus_tag="KR231_001878"
                     /EC_number="2.7.1.156"
                     /EC_number="2.7.7.62"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional adenosylcobinamide
                     kinase/adenosylcobinamide-phosphate guanylyltransferase"
                     /protein_id="HBH0004255.1"
                     /translation="MSKIILVTGGARSGKSNFAEKLCFDRNNNTAYIATSIPFDDEMK
                     DRVKKHQENRPRNWNTYEIYEDIYSIIKEIYKEHETVILDCVTLLVNNLMFEHNLNIE
                     ESSQEEINKLEQYIKEQVVKLIEEIEKTNLYFVFVTNELGMGIVPGNKLSRIYADIVG
                     RINQYIASKSNEVYFVVSGIAMKIKE"
     gene            19122..19895
                     /gene="cobS"
                     /locus_tag="KR231_001879"
     CDS             19122..19895
                     /gene="cobS"
                     /locus_tag="KR231_001879"
                     /EC_number="2.7.8.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenosylcobinamide-GDP ribazoletransferase"
                     /protein_id="HBH0004256.1"
                     /translation="MKRFILILQFLTRIPIKLNVGFDDEFYKSIVYFPLVGFVIGILS
                     YLIGWISMLLFEPFIASIIITLAGVLITGGLHIDGLGDTFDAIYSYRDKEKMLEIMKD
                     SRLGTNSLLAIMFVLLLKVGFVYDIISNNSLWVIIFMPMIARLGVMLLTYKTVTPREK
                     GMGNLFIGKLTTSMLITAIIYTLLIVALITKFIFLLPNIVLIKVLGSIIVVFVFIILF
                     KKHIYKKIDGVTGDILGCGIELSELVYLIYIYLLIFMFF"
     gene            19915..20529
                     /locus_tag="KR231_001880"
     CDS             19915..20529
                     /locus_tag="KR231_001880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HBH0004257.1"
                     /translation="MIRLILIRHALTNDNKKGRLSGHINSCISEEGKLQINKITRYLS
                     NENIDKVYTTPSTRTKDTVEKISKLKLLEIEEKEALREISFGDFEGRTFEEIKIKYPN
                     EFEKMIKEGNNYRYPNGESLIDSYKRVAKEIDNIILENDSNLDTKTILICSHAGTIRN
                     IITHLISGSYKYHWNFKIDNASITVLEIDGGFAVIDKMNFTDFI"
     regulatory      20596..20775
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00174"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="cobalamin riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="adenosylcobalamin"
                     /db_xref="RFAM:RF00174"
     gene            20905..22404
                     /locus_tag="KR231_001881"
     CDS             20905..22404
                     /locus_tag="KR231_001881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobyric acid synthase"
                     /protein_id="HBH0004258.1"
                     /translation="MLQGTASNVGKSVLVAGLCRIFKQDGYTVAPFKSQNMALNSFIT
                     KEGLEMGRAQVFQAEAAKIEPIADMNPVLLKPSGNNKSQVIVRGKVVGEMPSSKYHDY
                     KLELVDVLKETFNSLNSRYDIVVMEGAGSNAEINLKDRDISNMGMAEIADAPVIIVGD
                     IDRGGVFASLAGTMLLLNEDEKRRVKGVIINKFRGKKELLQDGVKMLEDIIKVPVIGV
                     VPYTDIKIEDEDSVTTRFKKKMNKSDIHIEIIRTPHMSNFTDFNIFETQEDVSIRYVD
                     YGESLGNPDILIIPGTKSTIDDLTYIRKSGLESQIKNLHSQGKLIFGICGGYQMLGKK
                     LKDPYHVESEIEEVDGIGLLDTETTFEKEKTTTQVEATIVECISEYMNNLKGKKVKGY
                     EIHMGITKRGNDVRSLDLITKKLDKEVNYTEGSVNKEGNVIGTYLHGIFDEISFTRAI
                     LNNIRKKKGLGELESKVNSFNEFKDKEYDKLADFLREHLDIEKIYEIMK"
     gene            22443..23819
                     /locus_tag="KR231_001882"
     CDS             22443..23819
                     /locus_tag="KR231_001882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobyrinate a,c-diamide synthase"
                     /protein_id="HBH0004259.1"
                     /translation="MKKILIAGTNSGVGKTTISLGIMQALVKRNMKVQPYKVGPDYID
                     PSYHTFITGRHSRNLDSYMLDDEKIKYIVNKSSKDADISVIEGVMGLYDGFGIDLDNC
                     TSSHTSKVLKSPVILVINGKSMAASSAAMVLGYKELDKDVNIKGVIVNNVKTNSHYQI
                     IKSSIEKYCNVEVLGYFPPNNKFSLESRHLGLVPSVEMKSLREKFYTLADEIEHYIDI
                     DRIIEISESDEFESDFDFQTLIENNKIKEHVNNKSIAIAYDKAFNFYYRENIELLEEL
                     GLEINYFSPLEDVSVPNADYIYIGGGFPEIFGKELEANESMRTSILEAHNNNIPIYAE
                     CGGLMYLGEKLLNQEEQEFNMVGIFSGISKMTSSLKRFGYCIGVAKENTLLSKKGESI
                     KGHEFHHSIFESDEKCVYSMRKERDGNIVEEWDGGYSKGNTLATYLHTHFYNNLNCIE
                     NFLKKGNE"
     gene            23820..24791
                     /locus_tag="KR231_001883"
     CDS             23820..24791
                     /locus_tag="KR231_001883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalamin biosynthesis protein"
                     /protein_id="HBH0004260.1"
                     /translation="MSILSIYIGYVTDLIVGDPYSFPHPVRFIGKLINFTQGIIRKVS
                     KNDRQLKLGGFILWFITVGITYLTTYAIVKLFSFNILLSIVVNSFIIYTTLATKCLKD
                     EALKIYNVLKTEDIEKSRIQLSYIVGRDTTNLSEPEIIRATVETVAENTVDGIIAPMF
                     YAFIGGAPLAMAYKAINTLDSTVGYKNKKYKDIGFASAKIDDIANYIPARISVILMTI
                     GSFFLNYNYRNCFKISIRDRKNHKSPNCAFSEGAVSGALGIQLGGTNVYFGEKVYKPT
                     IGDKLREIDKEDIIKTNKIMYASSFVSMLVFTLIYVLCRMILINLII"
     gene            24823..25893
                     /locus_tag="KR231_001884"
     CDS             24823..25893
                     /locus_tag="KR231_001884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class I/II-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="HBH0004261.1"
                     /translation="MKDLGHGANVDEMARLYGKNPKEIIDFSSNINPNVLPNLERYIL
                     KGLEECRNYPDINYTNLRENISKYIDINPDFIIPGNGATEVIYLLMKSIKKKLAIINP
                     TFSEYRRSAELNNLDIIDLELDLENNFKLNIDIIKENIKRFDSLFICNPNNPSGNVQD
                     LKELVHLLDKHNKVLIIDETFMEFVEDESKYSLVKYIESNKNIFIIKAVTKFFGMPGL
                     RLGYGLTSNTEIMNKIYEHKEPWTINSFADILSNFIFEDKEYIKNSKEYYIEEREYML
                     QELRNIRNIKVYDTDANFILIKIYKKTTKELKKDLFKQGNILVRDASNFIGLDDSFIR
                     VAIKSHEDNKILIENMKNLLGD"
     gene            25895..26782
                     /locus_tag="KR231_001885"
     CDS             25895..26782
                     /locus_tag="KR231_001885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalamin biosynthesis protein"
                     /protein_id="HBH0004262.1"
                     /translation="MKSYGICPASCGEFVQGIIDDEEYLCSYAIDMYSKVYIEEKLVD
                     INLGRYKSRLAIEKVFEKFNLPKKYTKNISLNINSKIPVGKGMASSTADIGATIKATL
                     SLIDKDLSSEEISKLAAEIEPTDSIFIDKNSIFNPLNGTVIKYLGNLTNAKVVILEPN
                     KVLDTMKIRLRQDYNKLKVENKEVIKKSFALLEEGLKKNNLSLVGEACTLSSLANENI
                     EKKEYLNEIIKISKKYGAYGVNIAHSGTVVGILIDKFMNDKKMIDALCESNINSVYNK
                     IYTQNIINGGIKGEIEWNT"
     gene            26770..27402
                     /locus_tag="KR231_001886"
     CDS             26770..27402
                     /locus_tag="KR231_001886"
                     /EC_number="5.4.99.60"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003724727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalt-precorrin-8 methylmutase"
                     /protein_id="HBH0004263.1"
                     /translation="MEYIKNPMKIEEKSFELIQEIIDEIRPDYKFKNNIEEKIIKRAI
                     HTTADFDYLDILKISEEAVDSIIDALKNNASIYTDTNMALSGINKRKLESLGCKYKCL
                     VADDETVKLAKEKGITRSMAAVEIAAKEEGRKIFVLGNAPTALYKVMEMKSEGRLDLD
                     AVIGVPVGFVGAQESKDEVEKTDIPYIISKGRKGGSNLAAAIVNAILYTM"
     gene            27411..28637
                     /locus_tag="KR231_001887"
     CDS             27411..28637
                     /locus_tag="KR231_001887"
                     /EC_number="2.1.1.195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalt-precorrin-5B (C(1))-methyltransferase"
                     /protein_id="HBH0004264.1"
                     /translation="MEEYVYIDGKKYRRGYTTGSCATGASKAAVYMLITKNRINTINI
                     DTPKGIPLLLKVDNINISDTFVECSIKKDGGDDIDATHTMDIYARAEIVAKNDKNKGY
                     LTLKDIDSLSTNSECKSELYKFIRVYGGTGIGVVTKKGLSVDVGKPAINPTPLKMINH
                     EIRKLIGDNFESILGNDKVLKITIFAPQGETVAKKTFNPRLGIVGGISIIGTTGIVEP
                     MSDDGWKKSLSIELQMKKEQGLDKIILVPGNHGEQFIREKLNLDIKYVVRVSNFIGYM
                     IKEAQRIGYKKILMAGHIGKFIKVSAGIFNTHSKVADARSEILVANLALMGARYEFLN
                     KINQCVTTEEAVELINNSEYREVYNILSNKCRERVKQYLNEDSDDIDVEVIIFSMDKS
                     LLGKSDNTDDLVEVFI"
     gene            28634..29242
                     /locus_tag="KR231_001888"
     CDS             28634..29242
                     /locus_tag="KR231_001888"
                     /EC_number="2.1.1.289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalt-precorrin-7 (C(5))-methyltransferase"
                     /protein_id="HBH0004265.1"
                     /translation="MINIIGLGPGNLDYITKKGENLISTSDVLIGGKRNLESIKNFEG
                     EKIVLDSNLREIIEYINNNKEKQISIIASGDPLIYGIGRYLSKNIDNKMLNMVSGISS
                     LQYIFSKIYVDMNDVYITSSHGKVPDFDYILSHKKVCMVTDSKIGPKQISREIIDRNL
                     NKIIVVGENLSYDNEKITIAKPEEIIRMDNFDMNVVVILDEE"
     gene            29232..29807
                     /locus_tag="KR231_001889"
     CDS             29232..29807
                     /locus_tag="KR231_001889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="decarboxylating cobalt-precorrin-6B
                     (C(15))-methyltransferase"
                     /protein_id="HBH0004266.1"
                     /translation="MRNSEFITGKVPITKEEVRAISISKLNLVNAKNLIDIGAGTGSV
                     SVEAAYNYPNLKVISIEKNDDAIELIEKNKKKFNLKNIEVIKGYAPINLGLNVKVESI
                     FLGGTGNNLEEIIEWSKKNLVTGGRLVANFIIIDTFNQTLKLLKKHGFKEIDVCVLNV
                     SKLEKLGKGEYFKPLNPIYIISCEKGENDDE"
     gene            29800..30552
                     /locus_tag="KR231_001890"
     CDS             29800..30552
                     /locus_tag="KR231_001890"
                     /EC_number="2.1.1.271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906481.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalt-precorrin-4 methyltransferase"
                     /protein_id="HBH0004267.1"
                     /translation="MNKVHFVGAGPGDKELITLKGYKLLSNADVVIYAGSLVNPELLE
                     YCKEDCQIHNSAHMDLQEIIDVMREGIENNKSVVRLQTGDFSIYGSIREQVEDLNKLN
                     IDYDCTPGVSSFLGAASSLGVEYTVPEISQSVIITRMEGRTPVPEKESIQSYAKHQTS
                     MVIFLSVQEIEKVVSKLLEGGYPKDTPIAVIYKATWADEKIVKGTLSDIAVKVKENNI
                     NKTALIMVGRFLGEEYNNSKLYDKDFKHEYRG"
     gene            30536..31657
                     /gene="cbiG"
                     /locus_tag="KR231_001891"
     CDS             30536..31657
                     /gene="cbiG"
                     /locus_tag="KR231_001891"
                     /EC_number="3.7.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalt-precorrin 5A hydrolase"
                     /protein_id="HBH0004268.1"
                     /translation="MNIEGNIAIICITENGKKLALKINSLVNNCVIYHVKNKKSNLVV
                     EETCVHTVQKKLSDFVGEIFSKFDYIVFIMATGIVVRSIAPYIISKFSDPAILVMDEK
                     GKNVISLLSGHIGGANSLTQYISSLIDANPVITTATDINQKASLDMIAKKLNAHIDNF
                     RESVKEVNSMLVNNKCVGLYIDEGYQVDTRGFKLIESKDELRDSFSNTYIEKLVVVSN
                     KINCIEDIENLNLDNKFEHCYSTKKIIKVIPRDIVIGIGCRRNTDSELMYNSLEEFLN
                     KQNIDIRAINTVGSIELKKDEKAIIELSKILKVPFKTFSVDEISKVDNLFDKSDFVKK
                     NVGVYSVAEPVAYLLSKGNLLVEKHKYKGITFSVGRIKI"
     gene            31654..32379
                     /gene="cobJ"
                     /locus_tag="KR231_001892"
     CDS             31654..32379
                     /gene="cobJ"
                     /locus_tag="KR231_001892"
                     /EC_number="2.1.1.131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011701973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="precorrin-3B C(17)-methyltransferase"
                     /protein_id="HBH0004269.1"
                     /translation="MIYVVGIGPGSKDTMTLEAIKAIEDSEAIVGYKTYIKLIEEFIQ
                     DKEIIQNGMRQEVDRCKQAVEEAKKGKKVAVVSSGDAGIYGMAGLILELISKEDEDIK
                     VKVIPGVTASIGAAAILGAPIMHDFCHISLSDLMTPWEVIEKRLRLAAEADFVICLYN
                     PRSKGRSEHLSKAFKIMGEFKGGDTPVGVVKDVGREKEEKFVCTFENMDFEKVDMTTM
                     VIIGNKSTYINGELMITPRGYTV"
     gene            32376..33128
                     /gene="cobK"
                     /locus_tag="KR231_001893"
     CDS             32376..33128
                     /gene="cobK"
                     /locus_tag="KR231_001893"
                     /EC_number="1.3.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="precorrin-6A reductase"
                     /protein_id="HBH0004270.1"
                     /translation="MILILGGTSDSLSICDKINELKNQPYILSVTTDYGRELAQQHAE
                     NVILGKLGKEDMLKFIKDNNIVKIIDATHPYAVEVSKTAITCAKLLNIDYIRFERKSL
                     IEEIDYDNKFIVDTIEEACEIANKIGTNIFIGTGSKNLNRFIEEISDKNLVVRVLPTS
                     EVILSCEKLGLSADNIVAMKGPFSQYINEETYKHYNIDLVITKESGIAGGFLEKVNAC
                     KTFNIPVIIIKRESINYENVFNDINKIKDILV"
     gene            33147..34625
                     /locus_tag="KR231_001894"
     CDS             33147..34625
                     /locus_tag="KR231_001894"
                     /EC_number="2.1.1.151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891951.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalt-factor II C(20)-methyltransferase"
                     /protein_id="HBH0004271.1"
                     /translation="MKKALLVVSFGTSYHETREKTIDICEDKIKNSLKSHDFFRAYTS
                     NMIINKIKKRDGIEIDNPIQALDKIYEQGYDEVIIQTLHIICGEEFNKLKEQVDGYSS
                     KFKKIVLGRPLLTHIEDYQEAVEAIKHQIPHMESNEAVVFMGHGTLHESHSAYPALEY
                     MLRDNGINAYVGTVEGYPEIEHVIRRLKEGNIKTVNLMPFMLVAGDHAINDMAGDEED
                     SWKTILEENGFNVRVHLKGLGENSYIQDKFVRHAVKCAENAKFYGIGAGPGDGSLLTI
                     KAVNTLKKLDILYTPESKKGGDSLALSIVSEYLPESVEIKSRHFPMSFDGNEKSLAWD
                     NVAQEIISDVNDGKNVGFVTLGDPMIYSTYVYIMKRILGEVEVETIPGISSFSNIASN
                     QNFPLVMDKEALVVIPCTMEDDKIEYALQNYNSIVLMKVYKNFKEIIKKLEKYDLIEH
                     AILVSNSSQESENVFTDLKEAHLEDKISYFSTILVNKDNKIK"
     gene            34655..35560
                     /gene="hemC"
                     /locus_tag="KR231_001895"
     CDS             34655..35560
                     /gene="hemC"
                     /locus_tag="KR231_001895"
                     /EC_number="2.5.1.61"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylbilane synthase"
                     /protein_id="HBH0004272.1"
                     /translation="MNIVVGTRGSNLALIQTEWVINELKKKYPEISFEIKIIKTKGDL
                     IQNVSLDKIGDKGLFVKEIEQQLLDGKIDIAVHSMKDMPSYLADGLKFAHTPKREDPR
                     DVLILREGYKNLDDLPHGAVIGTGSKRRKFQLLKQRPDLNIVQVRGNVETRIRKIKDE
                     NMHGIVLAASGIIRANLQDKISSYLPVDVVIPAPAQGALAIEIRSNDSAIEGIVNSLK
                     DENTEIQILAERGFLDGVNGSCHIPMAAYCEIIQDKIHLTGLYGDSEGKKVVIKSIDG
                     DISSPRELGLKLAKLVLKEYENYEG"
     gene            35550..37049
                     /gene="cobA"
                     /locus_tag="KR231_001896"
     CDS             35550..37049
                     /gene="cobA"
                     /locus_tag="KR231_001896"
                     /EC_number="2.1.1.107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uroporphyrinogen-III C-methyltransferase"
                     /protein_id="HBH0004273.1"
                     /translation="MKGKVYLVGAGPGDYKLMTLKGLECIRKSDVIVYDRLANSSYLR
                     EAKPDCELIYVGKASSNHILPQEDINRIIAEKAKEGKIVTRLKGGDPYVFGRGGEEAE
                     TLVDEGIEFEVVPGITSAIGGLCYAGIPITHRDHASSFHVITGHLKGDDSGELNWNAL
                     ANNKGTLVFLMGISNLEKISENLMKEGKDKDTPVALISWATRYNQRVVTSTLENVYET
                     AIKEEVKPPTLIVVGSVVGLREKLNFFESKPLFGKSIAVTRSRNQNSVLVEKIMDLGG
                     NPIEIPTIKVEKIQNNINLENEIKNINKYNYLILTSKNAVEIFFEKIYEMNFDLRILS
                     NLKVCAIGSATSNELKKRGIIADIVPKKFVAESLYEELAPILNDDDNILIPRAENARD
                     YLVDKLKAICEVTEVHIYRTVIDEEKKGEILDILNSNDIDYITFTSSSTVNNLVEIIG
                     KENIKILEKIKTLSIGPITTETINSLGIKLYKESATSTIDSLVDLIIKN"
     gene            37066..38031
                     /gene="hemB"
                     /locus_tag="KR231_001897"
     CDS             37066..38031
                     /gene="hemB"
                     /locus_tag="KR231_001897"
                     /EC_number="4.2.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="porphobilinogen synthase"
                     /protein_id="HBH0004274.1"
                     /translation="MLRRPRRLRASKAIRNLVRETKVNVEDLIYPLFVVEGENIKEEI
                     KSLPDVYHLSIDMLEDEIKEISELGIEHIMLFGVPDEKDECASQAFNDNGIVQKAIRK
                     VKEINSDINVITDVCMCQYTSHGHCGILTDTGYVDNDKSLEYLAKISVSHAKAGADMV
                     APSDMMDGRIQAIREALDENGLENVGIMAYSVKYASNYYGPFREAAHSAPSFGDRKTY
                     QMDPANSNEAIIETELDILEGADILMVKPALSYLDIIRRVKDNFDLPLAAYNVSGEYS
                     MLKFAVKEGLLNEDVILESITSIKRAGADIIITYFAKDIAKLLKK"
     gene            38184..38762
                     /locus_tag="KR231_001898"
     CDS             38184..38762
                     /locus_tag="KR231_001898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional precorrin-2
                     dehydrogenase/sirohydrochlorin ferrochelatase"
                     /protein_id="HBH0004275.1"
                     /translation="MLYPINLKLDELDVVIIGGGEVAYRKCKNFLEFNKNVTIVSKQI
                     LNKFYDLKGNIKIIKDDYKEIYIKDASVIIAATNNRELNMEIGLYCKAKNKLVNVVDN
                     IEISNFTVPSYIKRGDLLISVSTGGKSPSLSSKIKKEIEERYTEDYEEYLNVLGDIRK
                     KVIKKYEDKSKRKDVLNMLVTLDLEELKKFDI"
BASE COUNT        15514 a         4091 c         6846 g        12401 t
ORIGIN      
        1 atttaaatat agaaaggaaa atatatgtac aacaatatca aaaatatttt aaaagaaaat
       61 catataacgt ttgaagaata tgaccatgaa cctattttat catttgaaaa agctaaagaa
      121 ataagagaaa aattacaata tactggagta gaaagtaaaa gtttatttat aaaagatagg
      181 tctggaaatt actatatatt tgtaaccaca gaaggaaaaa aattagatcc aaaaactata
      241 aaaaatgttt taggtggaaa agtatctata tgttcaaaag aagaattaac acaaaaaaca
      301 caatgtttgc ctggatgtgt atctcctttt ggatatgaga aaaatatctc tcttgtaata
      361 gatcaagata tatttaacca tgataaaata atcttttcac cagggatacc agaaaagaca
      421 tttattatta cagctagtgg atttaaaaaa gtaataaata atataaacaa tacaacttat
      481 aaatatatat atattaatga attttaatca taattgtaaa ttagagaaaa taacattaga
      541 aatcatgctt aactatagtg taaataaatt atattcaaca caaaagattg atactattat
      601 tacaatagtt actgttaagc tcaaattcaa tgtattatga gttattattt ttaaatttta
      661 attacaaaag cagggtagtt ttaactactc tgctttatat ttaacataaa atatataaaa
      721 tcaacaaaat gattttagtc tatctattag atattcttcg ctctcaatgc ttagaacttt
      781 tagatatata caataagtgc tttcatttgt aaaaatttct atagtattat cttgtttatt
      841 tacacctaca atatctttaa aattgatatg atttttagta tttttacatt tgaaaatata
      901 tctgttatca attaaaatct catcattagt aattgaaata tagggtttat ctcatgcttt
      961 attaaaaatt tatatgtttg ttcaagataa aaacttacaa ataataatag aaaagttact
     1021 ttaaatgtac atattatcga aaatattatc acaaaaatac ttataatata tatttgttta
     1081 aaataacctc tatcgcaata gtttattaac gatatggaaa taaaagtgtt aaatcagatt
     1141 ttggagaaat aactttaaat atttccagac tctttttaga cagcctccat aaccttatat
     1201 tgaacctatt tattaacttt gtacttacat ataccactta tataagtttc gtatatatta
     1261 aagtccttat ctgttactat aaaatctgcc tccatacctt gatgtatgga gccacaaaca
     1321 ttatcaatat tacaacttaa agcagggata tatgtagcca tttttattgc atcttctaaa
     1381 gtggctatgt tccaatcaac tatatttctc acagccttgt ccatagttaa tacacttcca
     1441 gctaaactcc cactatttaa tcttgcaaca ctatttttta catttacatt aaacttacca
     1501 agagtatatt ttccatcctc catagcacca gctctcatac aatctgtaat taaagctatg
     1561 ttattactag acttagcatc catcattatt ttaacagcta ttgggcttac atgatgacca
     1621 tcacaaatta attcagcata agtatctttt agtaccatag cagccccaac cattccaggt
     1681 tctctatgat ttaaaggact catcccatta tatgtatgta caaacacttt agcacctgaa
     1741 ttaacgactt gtttaacttg ctcaaatgta gctgaactat gaccaagaga aactgatata
     1801 ttatttttag ttgcatatct tgttaattct attgaacctt tacgttctgg agcaattgct
     1861 atttttctta ttaaattttt cgattttttt tgccataatt ttaatatatt gatgtcaggg
     1921 tctttaaaat atttttcatt ttgagcgccc ttatattttt ctgtaaaaaa tggaccttct
     1981 aaataaatcc cttgtatttt tgcaccctca actcgattga agctattgct tatattttct
     2041 acagaatcac ttagtgtatc tacagaatca gttaaagttg taggtaggaa agatgttact
     2101 ccatatttta ataagccttt tgaaattgtg tttattgctt caaatgtatt gtccatgaca
     2161 tctgcaccta aaagaccgtg aatgtgagta tcaactaagc caggagcaat atatttacct
     2221 gaaaaatcta taacattatc agtaacatta ggtctttctt gttgaaattc accgaatttg
     2281 ccattaatta tactaaggta acctttttct ttgattccat gtttcataaa aaatttatct
     2341 gcataaataa aacttttcaa aataacctcc ttataattat attatcattg tggcattgac
     2401 gcttataata tcattctgtt ttcttgaaag ttatttaact tactatctta catgtcttac
     2461 tctatataca aatttatcac ttctagcgac actcaaagta aattcaataa ctatattgtc
     2521 atcattatat gtggtacgaa gtaatttcag acaaggtgaa tctcctggta cttccaataa
     2581 cttagcttcc ttatccgaga ttattccagc tgaaaattct tcatcagcaa ctttaataat
     2641 ctcgccataa tcttctctaa atatttcata taaaggtttt tgttcgattt tttcttttgt
     2701 caatcctata aattctttca taggaagata tgttctttca agcatcatag gaaggtcatc
     2761 agcaagtctt aaacgcatta tttttatcat tttttcacca ggagttatac ctaatttttc
     2821 agagaaatac tttgtacttt ctactacctc aaatgataat acctttgtac ctggcttttt
     2881 tccttgtgtt ctcatataat ctgtaaaact ataactttcc attaagtttt gagaattttg
     2941 acttagtgca gcaacaaaag ttccttttcc atgtcttttg tatatatatc ccatatgctc
     3001 taactcagcc atagctagtc taactgtggt tctacttact ccatattcat cacaaatttt
     3061 tctttcggaa agcattctat cgtttggttc catctcattt tcaatcttag ttcttaatat
     3121 ctcaacaagc tggtcatata ttggtctttt atcatttctt tttatcataa aaatatagtc
     3181 ctttctaagt ggttattacc acaatttgat tatagaatat agaattattt atgtcaatga
     3241 ataaagttta atcaaaattc aataagtaag gctattaatt tattataaaa ttatggtaca
     3301 ttgacaaaac aagtaaaata atttatattc aaattggtaa taaccacttt ggatatatta
     3361 tatgaggtat tttttatttt acagattaat ttattgttta gaaaagtaaa aattaataat
     3421 gaggagaatc tagtatgatt acagtaataa cattcaaccc atctatagat agaatgtata
     3481 gagtgaataa tataaacata ggtgaggtgc aaagggtagt aagtaagaat gcaactgctg
     3541 gaggtaaagg attaaacgta tctaaggtat gtaaaatttt aaaagaaaat cctttagcta
     3601 tgggatttct aggcggattt aatggagaat ttataaaaaa tgaacttaga aaactagata
     3661 tacaaaataa atttacaaaa atagagcagg aaactagaaa ttgcttaaac ataattgagg
     3721 acaataaagt tagtacagaa tttttagaaa aaggaccaat agtagaaaaa agcgatttag
     3781 agagatttga aaatgatata gaggaagtac taaaaaatac taaaatactg gtagcttctg
     3841 gtagttattg tgagaatatg ccgatagact attatgaaaa gataggaaat atatgtagag
     3901 caaataatat aaagtttata ttagatacat caggagaagc attaaaaata gctttaaaat
     3961 caaaaccata tttaataaag ccaaatatag atgaaataag acatttatta ggaataaata
     4021 tagaatcaag agaggaaatt atcttgtcag gaaaaaaact tattgaaatg ggtgcagaga
     4081 atgtatgtat atctttagga aaagatggta tggtgtattt aaacgaagat aacgtatatt
     4141 atgtaaaagt accagttgta aagtgtataa atactgtagg tagtggagat agcacagtgg
     4201 ctggatttag tgtaggtatt ttaaggggtt ataaaataga aaatttactt aaatttgcaa
     4261 atgcttgtgg tataagtaat gctttaaata tggaaactgg atttgtagat ttgggagaaa
     4321 ttgataaata tcaagattta gttgaagtaa aaaagttaag ttaaatacat ttaatgggaa
     4381 tataataaat ttaatgttgt tgtaatagat tttaatttta atataaaaga tatagtctta
     4441 tataaaaata ggttagaaaa attcattttt aacctatttt tataataaat atctatttta
     4501 ctgaatttat aattttctct agtaatcttt gagccttgat acactcttct ccactgatag
     4561 ctggttttat attattttct atacaatcaa taaaatgatt tgatatatcc tcaaaaccct
     4621 tttgttttaa tatatttacc catgcaccac tttgctttaa agttaggttt ccaccttctt
     4681 ctatttccag tacattaaga ttcttaactc tttgaatctt accctttgaa agaatttcaa
     4741 cttgttctaa ctttgttcca gaatctctat gcatagaggt gtttatagag aaatttttac
     4801 ctttaagttt atgacttaca aatataagat tcttattgtc tgttaaaaat aaatcctctc
     4861 cactaatttc aacatcttca tttgctaacc ataaagcagt gtcaataaca tgtatatagt
     4921 catctataag agtactgtcg aatttaacat ttcttaagga atttaatcca tgtttacata
     4981 tattgataga tacaatttct gtagcattat ttttaatttc tttgtacata ggacagaatc
     5041 tacggttgaa tccaaccatt aaatttaagt tttttttcgt acttaattcg ataagttctt
     5101 ctccttgact tactgttgaa gcaagaggtt tgtctacata tacatgaaca cctaaattta
     5161 ataatatttt tataatttcg tagtgtgttt ctgtagagct atgtagaaaa atacaatcac
     5221 attttttagc tagggattca atagaatcga attgcatgat tctataatca ctacagactt
     5281 tttccctttt aactttattt ggagtaaaag ctcctacaaa ctcaaatctc tcagacttag
     5341 ttaatatagg taaatatgcc ttttgagcta tggagccaag acctatcatt cccattttta
     5401 tatttttcat aatactttct cctaaggttt ttatatttac agaattgatt ataattcaga
     5461 cacataaatt tgtaaacttt gtatcaaaaa ataaatttaa agcttatata agtaaattag
     5521 cgaaataaga aatattgata aagtaatttt gtaggatatc tataaaattg attgatataa
     5581 atattttatg tattgacaaa aaattcaaat taatttatat ttggattagt ggtaattacc
     5641 actttggtct gaacaagttt ttatcgtaaa ataaaaatac taaagtatat agagtatgat
     5701 tttattaaat ttttaaagat aaactataaa attaattaaa atctatagtg tatattttat
     5761 agtgagttta agtagtacta aaaatctaag caaaaaatta taaaagagta tattttttta
     5821 tagtttaaag tggttataac ctcattacca aatgtaaacg ttacaagtat gaaaggagaa
     5881 tgaaaatgtt taaattagaa gaacaaaaac taaaagattt aggtgcaata ataacaacta
     5941 atgaaataaa acaacagcct gaattatggt tagagactta tgaaatatat aaatctaaca
     6001 aagaaaaatt aagtagattc atagatacaa taagtaataa tcatgggcag tttagagtta
     6061 tatttacagg tgctggaact tcagcttaca taggaaattc aatacttcct taccttaaaa
     6121 ataaaaatga cataagaaaa tacatatttg aagcaatacc tactacggat atagtttcaa
     6181 acccatatga ttacttaaaa aaagatatac caacattatt aatttcattt gcaagaagtg
     6241 gaaatagtcc tgaaagtttg gctgctttaa atttagggaa taagattgta gataattttt
     6301 atcatttagc tataacttgt aatccagaag gagaactagc taagatgact aaaaacgacg
     6361 aaaataatta cttgttatta atgccatcaa aatcaaatga tgaaggcttt gccatgacag
     6421 gaagtttttc gtgtatgatg ttatctgcta tgttaatatt cgatagttta gaagatgatg
     6481 tagaaaagtc atatataaat gcaatagttg aaatgggaag aaatgttata gatagaaaag
     6541 atgaaataca tgagttaata aataaagatt ttgatagagt tgtatattta ggttcaggag
     6601 gattaggtgg tttgacacaa gaagcacaac taaaactttt agaacttaca gcaggaaaaa
     6661 tatctacagt gtatgattct cctatggggt ttagacacgg accaaaatca tttattgatg
     6721 aaaatacact tgtatttgaa tttgtatcta actgtttata tacaagaaaa tatgatttag
     6781 atgttttaga ggagataaaa agggataaaa ttgctaaatt cacttgtgca gtgtcagtag
     6841 aaaatgaaaa taacttctca ggaacaaagt ttgagtttaa agaaaagtat aataaattac
     6901 cagatgtgta tcttgcaatg ccatacatat tgtttgcaca aactatagca ttgtttgtat
     6961 cggtaaaggt tggaaataag ccagatacgc catcagctac aggaacagta aatcgagtag
     7021 taaaaggtgt aacaatatat gaatattaaa agataagatt aaaatattat aactaaataa
     7081 tttgggaggg tatcaatgtg gcattagtaa caacaacatc aatgcttaaa aaggcacaag
     7141 atgaagggta tgcagtagga gcatttaatg tagaaaatat ggaaatggta attgctgtta
     7201 tagaagctgc tgaggagtta aattctccag taatattaca aactactcca tctactgtaa
     7261 aatatgcagg tcttgattat tatctagcaa atgcaaaggt tgctgcagaa agagtaaaga
     7321 tacctgtagc aatgcatctg gaccatggtt caagttttga ccttgcaatg aaagctttaa
     7381 gaagtggata tacatcaata atgatagatg gttctcatga aagctttgaa aataatatat
     7441 ctatatctaa atcagtagta aaagcatgta gtccttctct tataccagtg gaagcagaac
     7501 ttgggaaagt tggtggaaaa gaagatgatt tagatggcgg gaatagtaat gattatacaa
     7561 atccaaaaga ggcaaaagag tttgtcgata gaacaggaat atcttcattg gctattgcta
     7621 taggtactgc acatggattg tataagggtg aacctaaaat agatttagat aggttatcag
     7681 aaattaaaaa tgtagtttca atacctttag tattgcatgg aggttcagga atacatgatg
     7741 atattataaa agaagctata aaaagaggta ttgcaaaagt taactatgca actgaattaa
     7801 gaattgcata tagtaaaggg gttaaaaaag ttttagatga agattctgag gttatagacc
     7861 ctaaaaagta tggattagca gggcttcaat cagtaaagga ttttgtgaaa gaaaagatta
     7921 aagtgtgtgg gtctgtaaat agagtataaa aataaaatat cctaaattta ttttagataa
     7981 gtttaggata tttgttatat gaaaaattta tattaattat atgtaaatgg tgtatttttt
     8041 tcatttaatt gatgaaaaat atcagctttt attggtaaag tattacatat ataattaaaa
     8101 tatactaaaa attgaactat atattttatt attataaaat atttatatta aattgtggaa
     8161 ttaaaatata ctaggatata aaattcttaa ataaaaagaa aagattgttt ttataaaaaa
     8221 tattttttat accacttaaa aaaacacaat aataacactg agggaggtgg ggatatgaga
     8281 gaacgcatta ttcttgaaac attaaaaaat agtagtggtt atctaaacat agattatttt
     8341 gcagataagt tgggggtatc tactcgaact atcagaaatg aaataaaaaa gatagaaact
     8401 ataaaagaat gtaatggttt taaattagaa tataagtcta aattaggata tattctaaat
     8461 attaaagacc aagataaatt cgagcattat ctaagaaact taccctcaga tttagttgaa
     8521 aatccagaac aacggttaga gtctataata gtagaacttt tagtaaatga aggttataaa
     8581 actatagaac agttaagtaa aaaatttcta gtaagttcat cccaaataaa aaatgattta
     8641 aaaaagatag atgaaaagat aaaggataca gaattaaaac tagagcgaaa ggctcattat
     8701 ggaattaaaa tagaaggttc tataaaagaa attcaaagta tattggtgga tagttatttt
     8761 agagggaata gaaatataac agagtacagg aataagttta tagataattt aaaattagct
     8821 aatattagaa gtacaataaa aaatgtactt aatgaacatg atttagaagc aaatttaaca
     8881 gaacttgagg aaatattagc acaaattatt atattgtata taagagttag tatgagagta
     8941 gcgggaaatg ctagcgattt aaaattatat acagaagatt taattataga taaattatta
     9001 gataaaattt ttagagataa aaaatataac cttaattatg atgaaaagta ttatttaaag
     9061 gagcttataa aactaaagac taaagataag aaagccacta taaagaatat tgataagaat
     9121 aaacttcaag atattatgtt cgaatttttt agagagatag ataaaaaata taactctaat
     9181 tttttagaag ataaagagtt ctttaactta ttttacttac atattgcatg tttaatagaa
     9241 cgtataaaga agaaccacaa gataataaat cctttttcag ttaaaataag tcaacagtat
     9301 ccaactgttt ttaatttatc tattcaattt tcaaaaatca tagaaaatga gtatcatata
     9361 aaaataagtc aagatgaaat agggtttata gctactcaca ttgctgttcc ttttgaaaag
     9421 agagaagaag ctaattttaa taaaaaatat aaaatagcaa taatatgctc ttctggtgga
     9481 ggtagtgcat ttttgataaa tttaagactt aaagaaattt ttccaaatgc tgagataaga
     9541 aatttttcat tactagaaga aaaagctgta atagaatttg caccagattt gattttttca
     9601 ataacaaatc ttttatttga aataaatgct ccagttatac ttataaatga aattttagac
     9661 gaattggatt atttagatat taaagaaagt gttagatttg cagaccatat aggaaatata
     9721 tcaagcccaa aacaatatat attaggtcta tttgataaga atcactttag gtgtataaaa
     9781 gataaagcta agtataagga tatccttgat agtatgtcaa aatgtatagt tgacgagggc
     9841 gcttgttctc caacctatcc caaagatgta tgggaaagag aaagctattt gagtactatt
     9901 tatacaaatg gggtggctat acctcatcca atcgagatga caggaaacaa aaatataata
     9961 tcagtagctt tgatacaaac tgatattatt tatgaaaata gggtgcctaa aattattttc
    10021 atgatttcat taataaaggg aaatttagaa cttcataagc aaatatctaa atatttaagt
    10081 aagattatgg caaataagga tatggtagac atgctaaata agtcacaatc ttatgaagag
    10141 tttatgtata agttaaaaat ctatctggga ggttagacat gaatatagag ttttttaaga
    10201 ggttgtcaga agcagatggt atagcatcta atgaagaaga ggttagacat gttttattgg
    10261 aagaactaaa agcttatagt gataaaatta tctgtgatgg gctagggagt atcatctttt
    10321 ctaaaataaa agatgagagt gcaccaaacg taatgatttg tgctcatatg gatgaagttg
    10381 gatttatggt gagaagtata gacaaacttg gtatgattca cttaataaca ataggaggag
    10441 taaaacctct tgcacagttt gtacaaaaag ttagaattac aacaaaagaa gggaagaaaa
    10501 tccctgctgt cataaatgct acatataata atggtaaggc tgaaaatata tatgcagata
    10561 ttggagcata tacagaagaa gatgtatata acctagggat taatgttggg gatatggtaa
    10621 catatacaac aagctttgag gaatttactt taccagaccg attagtggga aaggcttttg
    10681 atgataggat aggatgtttt gtgatgggag aagttttaaa agaacttagg aaagaaaatc
    10741 taaattgtaa tattcacttt gcggctacaa gtagtgaaga ggttggaata aggggagcaa
    10801 agacatcaac acagttaata aatccagata tagtatttgt aatagatgta gcatgtgcta
    10861 aaaatgagtt tgtgagagac tatacaaatc agaaacaaat tgataaaggt gtaatgctaa
    10921 tgcatagaga taggactcta gtccctagta gaaaaatgat agattatgta atggaaattg
    10981 ctgataaaaa taatatacca cttcaacatg atatgtttga atcaggtggg actgatggag
    11041 gagaagcaca tctcgtaaat gaagggaaac cttgtgtagt aacttgtgta ccagttagat
    11101 atggtcattg tgcattttca atagtaagta ataaagattt agagaacatt ataagattgt
    11161 atacacagtt aattttaaat tttgatgaag aacaatataa acatataaga aattttatct
    11221 aaaggagaat aagaaaatgt caacagaagt acaaataatg gaacttatat caactgcagg
    11281 agagagtaaa tcgaaagctt ttgaggcttt aaaaaaagtg aagtcaaaag attttaaagg
    11341 agcaaaattg ttaatagagg aggctcgtaa aatagatatt gaagctcaca ggatacaaac
    11401 agaattaata actcaagatt taaatgaaga tgttgaaagt ccagcaatga gtcttttaat
    11461 ggtacatgct caagaccact atatgacttc tcagctagca aaagacttga tagaggcttt
    11521 gatatattgt cttgataagt aattgtaata tagaaataga ttatttatgt aaaaattctt
    11581 ttaaaagttt agatgctttt aagagataat aaaaatacaa actttaggag gaattattat
    11641 gaaaatatta ttatgttgtg caggtggatt ttctactaat atgttaatgc aaaatatgaa
    11701 aaaggtggta aaagagagtg ctaaactcaa tgaaaaagat tttgagttta cagctatacc
    11761 agcagattca atagaaagtg aagttgatga ttgggatata gtacttatag gtcctcaaat
    11821 agctcacaaa atagacttct taaaaggaat attagagcca aaaaataagc cttttgcagt
    11881 aatagataaa gatgtatatg gaaaaatgga tggagctaca gttatgaagt tggcattaat
    11941 aacttataag aaacatcaat tagctcaagg ataataaaaa taatgaggga aaagggagat
    12001 tagatatgtt ttcaaaattt gaagcattta tgaatagagt atttatgcct ttagctcata
    12061 aggttgacaa tcaacgtcac cttggttcta taaaggctgg tatggttgct atgacaccat
    12121 tcacaatatt aggaagtata tttgcaatac ttccagcact tccaaatatg cttggagaaa
    12181 ataatccaat aagcaaattc atacttaaca attcagcaat attggattta ccagtaagtc
    12241 tttccatagg tttaatagga ttatatgctt gtatgtgtat tgcttttaat ctggggaact
    12301 actataaatt atatatacca ggttgtgttg cactatcaac tttttctttt ttattcctag
    12361 tagcatcatt tacaccagat ggagctttag aaataggaaa tttaggagct aaagggctat
    12421 ttacaggtat gatagcaggg cttggttctg tggagttata taatttttgt aataagaaga
    12481 atatcacaat aaaaatgcca gaaaatgtac ctgattttgt atctaggtct tttgaattaa
    12541 tacctactac tataatagtt tgtggaactt ttatagttgc tcgttttatt tcattaaaag
    12601 tatttggaga attacctcca cagatactta ctcaattttt atctccatta gtaggaagta
    12661 tggataaccc atggtcagtt cttgcactta actttgctat atgtactata ttcttttttg
    12721 gaatacattc atcagtattt agtcctataa ctagacctat aatgattaca tttatagctg
    12781 aaaacatagc agctatgcaa gctggagaaa caatacctca tttctttaca gcaggagctt
    12841 caagtgcatt ctttggattt acaggatgtg gaattagtat aggttgtgta attgcatgta
    12901 tgttatcaaa aaatgcttcc tataagaaga ttggacgtgt atcattattc cctgcattat
    12961 ttgggataaa tgaaccaata ttatttggag caccgataat attaaatcca ataatgttta
    13021 taccacatgt atttggtgga gctataatag gtacactacc aatgtttttt atgcactggg
    13081 gatggttagc aaagccagta tttgaccctc catatgtagg ggtattctta gaaggatttt
    13141 taactaatgg agattggcat tctatattag caaatgcatt gcaattagta ttagcagttt
    13201 tattatattg gccattcttt aaaataatgg aacgtcaaca aaataataaa aaacaaaaag
    13261 aagaaactaa gaatatattc tctaaagaag aagaagactt attggatgat ttaggattgg
    13321 atttctaata ttttgttatg aataatacaa tggagagatt agtatcctta atctataaaa
    13381 gaggtgttga cgctcttttg attaaagcaa aaaatactaa aagatatata ggagctttat
    13441 caggtagtgg tgtatatgtg cttgttacta aggataaaaa ttatcaaatt ctagatggca
    13501 gatatattga tgaagcagat aaaaaaacga ctggtttcat aaaaaggatt gtatctcaag
    13561 gttcttatat accaactata attgagttat taaaagaatt aaatataaaa aagttagcaa
    13621 tagaaaacca agctatgagt atacaagagt atctttcact aaaaaatgaa ggttttgaaa
    13681 tcaatttaat aacaaatgaa ttatggaagc taagggctat aaaatctaaa gaagaaattg
    13741 aacttattaa aaaggcttgt gaaattacag atgaagtatt tgatgaggtt atttctgaaa
    13801 ttaaaaaaga tatgactgag ctagaagtat cagctctaat tcagtatcat gcattaaaaa
    13861 aaggtgcaag tggaatgtct tttgaaacaa tagtggtatc aggagaaaga ggtgcaatgc
    13921 cacatggaag acctacaaac aaaaaattga aagtgaatga agctataaca atagattttg
    13981 gtgttgttta tcaagggtat caatcagaca tgactcgtac aatatctata ggtaaacctc
    14041 ctaaaattat taaagagata tatgatgtag tattggaagc acaattatct gcaatagagt
    14101 caataaagga aggaactagg gcaagtgatg ttgacaaagt ggctagaaaa attatagata
    14161 aacatggatt tggcgaatat tttaatcatg gactgggtca tggtataggt cttggagatg
    14221 gtgaagtccc cactttaaat ccaaatagtg aagatatatt agtggaagga atggtaatgt
    14281 cttgtgagcc aggtatttat attccaaatg tagggggagt tagaatagaa gatgacattg
    14341 ttataataga tggaaaaggt gttccactca ataagacatc caaagagttt ataatattag
    14401 gagagtaaaa ttatgaaata taattttaat aaagtattaa atcgtaaaga aggaaattgt
    14461 agaaaatgga gcaaccatgt gattaaagaa aaattcggct taaatgaaga tgcaattcct
    14521 atggatttag ctgatatcga ttttgagtgt gctcctgcta taaaagaatc tatcttaaaa
    14581 agagcatcag taggagatta tagttatact tttataggag atgacttcta tgatgcgatt
    14641 ataaattgga ataaaagaag atttgatgta tatatagaaa aggattggat aaaattaact
    14701 tttggtactg tttcaaccct tcattatata gtccaagcat atactaaaga aggagagggt
    14761 gtattgataa atacacctgc ttatgaccct tttgcagagg ctgtagtaaa taataataga
    14821 aagttgtgtt gtagctcatt aaaattagat aacaatagat attatttaga tttagaggat
    14881 atggaaaatc aaatgaaata cgagaatata agattgctta tattctgtag tccacaaaat
    14941 ccatcaggtc gtatatggac aaaagaagaa ctatatcaag tgtcagagtt atgtttaaag
    15001 tataatgtaa ttttggtaag tgatgaaatt catagagata taatatttaa agattataga
    15061 tttgtatctt tatggaatgc tcatccagaa atttataaaa atagtataat ctgtgtatct
    15121 cctaataaag gcttcaactt aggtggatta aaaacatcat atgtattaat aagagatgta
    15181 aaaattaggg agactttatt agaaagacta aaaagtaatt caataacttc tccaaatgta
    15241 tttgcaatac cagcaatagt tgcagcatat aatgaaagcg aagaatggct agatgctatg
    15301 actagttatg tagaggagaa ttttgaaata gtttatgatt tctttgaaac taatatacca
    15361 aaagctaaag tgatgaagtc agactcttct tttttagcct ggatagatgt aagagaagta
    15421 tttagaaatg aagaagaatc taaagaattt tttagacatg caaacttaac tatggtagtt
    15481 ggaagttatt ttgtgaaaga tggagatgga tttattcgta ttaatgtggg gtgtcctaga
    15541 gaaacattaa atgaggctct aaatagaatc aaaaaaacgt atataagtat gtattgttaa
    15601 atcataaaaa aagtatctat ggtttatata aaaacacatt atttagttat caaatattac
    15661 tggaattttg tattccagta atattttttg attaaggaat attattgagg aatattaaat
    15721 aatattattt cataccctta tattaactta tataaaaata ttttattatt ttgggaacgg
    15781 gttagctaac ctttatctag tgtatattta tattgtaaga agcagtaaaa acttttcctt
    15841 tactaagttt attaataaac ttcttatctt tataaatttt gttagaattt atactatcag
    15901 caagaccata ccaaggttct atacataaaa aaggagcagt agaattagtt tcactataat
    15961 aaggagtcca aataccaact agagggaaat cttccataga tatagttaca tatttactac
    16021 catcattatt acatatagat acttcatcta tgttggtgta tatcaaagca tcattcttga
    16081 atacttctgg atttaactgt aagtttttta attttccaat aggtattata tcatctgtaa
    16141 aagaaccatt taaattgatt ttttctacat catttttact tttaaactca aggtagtgtt
    16201 tagaaaaatc attttgttcg taaaaaggaa ggttgaatgc aggatgtcca cctatagaaa
    16261 agaatatatc tttagaatca gtatttttta caatccattc tacctcaata ctattatcat
    16321 ttaatgtata gtttatgatt agctcaaaag aatatggata cttctttaaa gtagattcat
    16381 tatctgttaa tttataagtt acaaatgtat ctcctttatc tacaatctca aagtccatat
    16441 ctctagcaaa cccatgttga gtcatgctat ataaattttc ttctattatt gtttcattat
    16501 caaaaagttt acctactata gggaacaata taggtgattg tctaccccaa tattttttat
    16561 taccatccca aagaatgttt ttgtcgtatt ttttagaaaa tattttagtt agttcagcac
    16621 caaaactgct tgattcgata attaaatttt cattttgtaa tatattcatt taaaatctcc
    16681 tttattatat tttatgagta tattatacta taaagtataa agattattaa attttatttg
    16741 atattatatt tgaaaggtag attttagtat attttgaaaa ttttgttttg aaaatttggg
    16801 attatttaag aaattttgta ttataaatag aaggaaatag ataaattgta tagaataaaa
    16861 tatattaaga taagttaata atgttaaatg ggaagtgagt ttatggaaaa accaaataca
    16921 aaagttgtta actttcaaga gtataaagac agaaaaaacc aaagagaagt aaatagagac
    16981 gaacttttaa agcttataaa aaaaattgtg acttcaaaat agggagttgt taaactccct
    17041 attttaatgg gtttcataat aattaagaca ttctgagtcc atctatataa tctttgaatt
    17101 gtgagaaatc tgattcacta cttaattcta tggtttctga accttccgta taaaaattct
    17161 taagatagat agtataatta ttatcaacac aatcatgata aatacatcta tatccatctt
    17221 catacaaact ttttaactta gaaaaatcat ccacaatatc atctccttaa agttctttta
    17281 aatatatttt tacaaaaagc atctaattgt atgcaaattg acaatgtaaa ataaaggaaa
    17341 tgaacataaa atgtagaata atttttatat gtatgtaaaa ataaaaagaa aaagttgaaa
    17401 tttttagaaa ataagagtat tttttatcta aaaagagagt ttaaaaaata aaaaaatgtt
    17461 gggaggataa aaaatgagtt tattagaaag tatatcaaaa aacatatatt ccctagataa
    17521 ctcttctatt gaaaaaacaa agcagagatt ggataggctt atacatccaa ctggaagctt
    17581 aggaaagata gaagatattt gcatgcaatt agcaggaata tttggcaatg aaaattttga
    17641 cacaagtaaa aaggttataa ttgcttttgc gggagaccat ggtgtatatg aagaaggcgt
    17701 agcacctgac cctcaaaata taacaaaatt acagtttcca aatttttcga aaggtctatg
    17761 tggagttgga gtaataagta aatttgtagg ggcagatgtt gtagctgtag atgtaggaat
    17821 aaactgtgat gaaaaactgg atggggtatt agactacaag ataagaaaag ggacatcaaa
    17881 tatggcaaaa ggtccagcta tgagtaaaca agaagcaatt agatgtttag agataggtat
    17941 tgaaatagca gagcagtgta tagaaaaaga ttataaggtt attggtattg gggagatggg
    18001 tatagcaaat actactccaa gtacagcaat aatatctgta atttcagggt gtgacccgtt
    18061 agaagttact ggtataggtg caggtcttaa gaaagaaaga ctaaagcata aggctgaagt
    18121 aattagaaag gctattgaaa ttaataatcc aaatccaact gatggagtag atattttatc
    18181 taaagtagga gggtttgaaa taggctcaat ggcaggtgtt atattaggtt gtagtgctaa
    18241 taggattcca gtagtaattg atgggtttat ttcttatgca gcagcattaa ttgcatataa
    18301 gataaatcca aaaactagag aatatatgat agcatctcat ttatcagcag aatcaggaac
    18361 taaaagagca ttagacatat taaaattaga ccctctatta aatatggata tgagattagg
    18421 tgagggaagt ggagctgctt tagcatttga tataatagaa gcttcaaact atacttataa
    18481 aaatatggca acttttgatg aaattgacat gggaagataa atataaaaat ttaatatgta
    18541 ggagtgtttt gatgagtaaa attattctag taacaggagg agctaggtca gggaagagta
    18601 actttgcaga aaaactatgt tttgacagaa ataataatac agcttatata gcaacctcta
    18661 ttccatttga tgatgaaatg aaagatagag taaaaaaaca tcaagagaat agacctagaa
    18721 actggaatac ttatgaaata tatgaagata tatattccat aattaaggag atatataaag
    18781 aacatgaaac tgttatacta gattgtgtaa cattattagt aaataatcta atgtttgaac
    18841 acaatctaaa tatagaagaa tctagtcaag aagaaataaa caaattagaa caatacataa
    18901 aagaacaagt tgtcaaactt attgaagaaa tagaaaaaac aaatctatac tttgtatttg
    18961 taacgaatga gttaggtatg ggaattgttc ctgggaataa acttagtaga atttatgctg
    19021 atattgtagg tcgtataaat caatatatag cttcgaaaag taatgaagtt tattttgtag
    19081 ttagtggcat agctatgaag ataaaggagt agtatgcaat tatgaaaaga tttattttaa
    19141 tactacagtt tttgacaagg atacctataa aattaaatgt aggatttgat gatgaatttt
    19201 ataagtcaat agtatatttt ccacttgtag gttttgtcat aggtatatta tcctatttaa
    19261 taggatggat ttctatgctt ttatttgaac catttatagc ttctataata ataactctag
    19321 ctggtgtctt aattactgga ggacttcata tagatggatt aggagataca tttgatgcaa
    19381 tatatagtta tagggataaa gaaaagatgc ttgaaataat gaaagattca agattaggta
    19441 caaattcact tctagcaatt atgtttgtac ttttattaaa ggttggattc gtttacgata
    19501 taataagtaa taattcattg tgggttataa tttttatgcc aatgattgca aggttaggag
    19561 taatgttatt gacatataaa actgtgacac caagagaaaa aggaatggga aatttattta
    19621 taggaaaatt aactacaagt atgttaataa ctgctataat atacacatta ttgatagttg
    19681 ctcttattac taaatttata tttttattac ctaatatagt gttgattaaa gtattaggtt
    19741 cgattatagt ggtttttgta tttataatat tattcaaaaa acatatttat aaaaaaattg
    19801 acggagtaac aggagatata ttaggctgtg gaatagaact ttcagagctt gtatatttaa
    19861 tttacatata tttgttaatt tttatgtttt tttaaagtaa aaagtggtga taatatgata
    19921 agattaatat taataagaca tgcactgaca aatgataata aaaaaggaag attatcaggc
    19981 catataaata gttgtattag tgaagagggc aaactacaaa taaataaaat taccagatat
    20041 ctgagtaatg aaaacataga taaggtttat acaacaccat ctacacgtac taaagataca
    20101 gtagaaaaaa tatcaaaatt gaaattatta gaaatagaag aaaaagaagc tttaagagaa
    20161 attagttttg gagactttga aggaagaact tttgaagaaa ttaaaatcaa atatccaaat
    20221 gagtttgaaa aaatgataaa agaaggtaac aactatagat atccaaatgg agaaagtttg
    20281 atagactctt ataaaagagt ggcaaaagaa attgataata taattttaga aaatgatagt
    20341 aatttagata caaagacaat acttatatgt tctcatgcag gaacaataag aaatataata
    20401 acacatttga tttctggtag ttataagtat cactggaact ttaaaattga taatgcatct
    20461 attacagttt tagaaattga tggtggattt gctgtaatag ataaaatgaa ttttacagac
    20521 ttcatataat ttaatcaaaa ccaaacatta caatctgtgt ttgtaatata tctgtaaaat
    20581 tagcaatgaa aatagaatat tagattaaaa ttaggttctt aattagatgt taaaagggaa
    20641 aaaggttaga tgcctttgca gcccccgcta ctgtgaaacc aacgaaacta taaataccac
    20701 tgtcagtttg atgggaaggt tatagaagta ggatgaagtt aagccaggat acctgcctaa
    20761 tttaatttaa aacaagaggt cttcggggtg aaagattttt aattaatata tataaaagtc
    20821 ctatctttag aagtattagg acttttttta atttgttttt tagtaaattt taacaaggag
    20881 ggatggaaag tggggaaaaa aataatgcta caaggaacag cttcaaatgt aggtaaaagt
    20941 gtcttagtag caggtttgtg tagaatattt aagcaagatg gttatactgt tgctcctttt
    21001 aagtcacaaa atatggcttt aaattctttt ataactaaag aaggattaga aatgggaaga
    21061 gcacaagtat ttcaagcaga ggctgcgaaa atagagccaa tagctgatat gaatccagtt
    21121 ttattaaaac cttctggaaa taataaaagt caagttattg taagaggtaa agttgtagga
    21181 gaaatgcctt cttctaagta tcatgattat aaattggagt tagtagatgt gttgaaggaa
    21241 acatttaata gcttaaattc aaggtatgat attgtagtta tggaaggggc aggaagtaat
    21301 gcagagataa acttaaaaga tagagatatc tctaatatgg gtatggcaga aatagctgat
    21361 gcacctgtaa taatagtcgg agatattgat agaggaggcg tatttgcctc attagcagga
    21421 acaatgcttt tattaaatga agatgagaaa agaagagtaa aaggtgtaat aatcaataaa
    21481 ttcagaggaa aaaaagagct tttacaagat ggtgtaaaga tgctagaaga catcataaaa
    21541 gtacctgtta taggagtagt accttataca gatataaaga tagaagatga agacagtgta
    21601 actacgagat ttaagaaaaa aatgaataaa agtgatatac acatagaaat aattagaact
    21661 ccacatatgt caaattttac agattttaat atatttgaga cacaagaaga tgtaagtatt
    21721 agatatgtag actatggaga atctttagga aatccagata tattaataat acctggaact
    21781 aaaagtacta tagacgattt aacatatata agaaaaagtg gtcttgaatc gcaaatcaaa
    21841 aatttacata gtcaaggtaa attgatattt gggatatgtg gtggatacca aatgttaggt
    21901 aaaaaattaa aagaccctta tcatgttgaa agtgaaattg aagaagttga tggaataggt
    21961 cttttagata cagaaacaac gtttgagaaa gaaaagacta caacacaagt agaagctact
    22021 attgttgaat gtattagtga atacatgaat aaccttaagg gaaaaaaagt aaaaggttat
    22081 gaaattcata tgggaattac aaagcgaggt aatgatgtaa gaagtttaga tttaataact
    22141 aaaaaacttg ataaagaagt gaattatact gagggaagtg taaataaaga ggggaatgta
    22201 attgggactt atcttcatgg aatatttgat gaaataagct ttacaagagc aattttaaac
    22261 aatataagaa agaaaaaagg tttaggagaa ttagaaagca aagtaaactc ttttaatgaa
    22321 tttaaggata aagagtatga taagttggct gattttttaa gagaacattt agatatagag
    22381 aaaatatatg agattatgaa ataatgatga cctttattta taatttaggt aggaggtgta
    22441 ttatgaaaaa aattttaatt gcgggtacta atagtggagt aggtaaaaca acaatatcat
    22501 taggaataat gcaagctttg gttaagagaa atatgaaagt acagccatat aaagtagggc
    22561 cagactatat agacccttca tatcacactt ttataactgg aagacattct agaaatttag
    22621 attcttatat gttagatgat gaaaaaataa agtatatagt aaataagtcc tcaaaagatg
    22681 cagatatttc agtaatagaa ggtgttatgg gcttatatga tggctttgga atagatttag
    22741 ataattgtac aagttcacat acttcaaagg tattaaagtc acctgttata ttagttataa
    22801 atggtaaatc tatggcagca tctagtgctg ctatggtact tggatataag gaactagata
    22861 aagatgtaaa tataaagggt gttatagtaa ataatgtaaa gactaatagc cattatcaaa
    22921 taattaagag ttctatagaa aaatattgta atgttgaagt attggggtat tttcctccaa
    22981 ataacaaatt ctctttggaa tctcgacatc taggattagt tcctagtgta gaaatgaaat
    23041 cactaaggga aaaattttat accttagcag atgaaattga acactatata gatattgaca
    23101 gaataattga aatatcagaa agcgatgaat ttgagagtga ttttgatttt caaactttaa
    23161 tagaaaataa taaaataaaa gaacatgtta ataataaatc aatagctata gcatatgata
    23221 aagcattcaa tttttattat agagaaaata tagagctttt agaggaactt ggtttagaaa
    23281 taaactattt tagccctctt gaagatgtat cagtgccaaa tgcagattat atttatattg
    23341 gaggaggttt tccagaaata tttggaaaag aattagaagc aaatgagtca atgagaactt
    23401 ccatattaga agcacataac aataatatac ctatttatgc agaatgtgga ggactgatgt
    23461 acctaggtga gaaactattg aatcaagaag aacaagaatt taatatggtt ggaatattta
    23521 gtggaattag taagatgaca tcttctttaa aaagatttgg gtactgtatt ggtgtagcca
    23581 aggaaaatac tcttttatct aaaaaagggg aatctattaa agggcatgag tttcatcatt
    23641 caatatttga aagtgatgaa aaatgtgtat attcaatgag aaaagaaaga gatggaaata
    23701 tagtagaaga gtgggatggt ggttatagta aaggaaacac tttggctaca tatcttcata
    23761 ctcattttta taataactta aattgtatag aaaatttttt gaaaaaagga aatgaataaa
    23821 tgagtatttt atctatttat ataggatatg tgacagactt aattgtagga gacccatatt
    23881 cttttcctca tccagtgaga tttattggta aacttataaa ttttactcaa ggtataataa
    23941 gaaaggtctc taaaaatgat aggcagttaa aattgggggg atttatatta tggtttataa
    24001 ccgttggaat aacatattta acaacttatg ctatagtgaa gttatttagt tttaatatat
    24061 tattgagtat tgtagtgaat agttttataa tttatacaac actagccaca aaatgtttaa
    24121 aagacgaagc attaaaaatt tataatgtat taaaaactga agatatagaa aaatctagga
    24181 ttcagctatc ttatatagta ggtagggata ctactaattt aagtgaacct gaaataataa
    24241 gagcaactgt agaaactgtt gcagaaaata ctgtagatgg tataattgcg cctatgtttt
    24301 atgcatttat tggaggagca ccacttgcta tggcctataa agctatcaat acattggact
    24361 caacagttgg atataaaaat aaaaagtata aagatattgg ttttgcatct gctaagattg
    24421 atgatatagc caattatata ccagctagaa tatctgtcat tcttatgaca attggaagtt
    24481 tctttttaaa ttataactat aggaactgtt ttaaaatctc tattagagat agaaagaatc
    24541 ataaaagtcc aaattgtgct ttttcagaag gtgcagtatc tggtgctcta ggaatacaac
    24601 taggaggtac caacgtttat tttggggaaa aagtatataa gccaacaata ggggataagc
    24661 ttagggagat agataaagaa gatataatta aaactaataa aattatgtat gcatcttcat
    24721 ttgtatctat gttggtattt acactaatat atgtgttatg taggatgatt ttaattaact
    24781 taattatata aattattgtt tgttaactta agggggacat agatgaagga tttagggcat
    24841 ggtgccaatg tagatgaaat ggcaagatta tatgggaaaa acccaaaaga aataattgat
    24901 tttagttcaa acataaatcc aaatgtatta ccaaatttag agagatacat tttaaaagga
    24961 ttagaagagt gtaggaatta tccagatata aattatacaa acttgagaga aaatatatca
    25021 aaatatatag atataaatcc agactttata atacctggca atggtgcaac agaagtgatt
    25081 tatttgctta tgaagagtat taaaaaaaaa ttggctataa taaatccgac tttttcagag
    25141 tatagaagaa gtgctgagtt aaataattta gatattatag atttagagtt agatttagaa
    25201 aataacttta aacttaatat agatataata aaagaaaata taaaaagatt tgatagttta
    25261 tttatatgta atcctaataa tccgagtggt aatgtccaag atttaaagga acttgttcat
    25321 ttactagata aacataataa ggtattaata attgatgaaa ctttcatgga atttgttgaa
    25381 gatgaaagta aatatagttt ggttaaatat atagaatcaa ataaaaatat atttataatt
    25441 aaagctgtga ctaagttttt tggtatgcct ggtttaaggc taggatatgg tcttacaagc
    25501 aacactgaaa ttatgaacaa aatttatgaa cacaaagagc catggactat caattctttt
    25561 gcagatatac tatccaattt tatttttgaa gataaagagt atattaaaaa tagtaaagaa
    25621 tattacatag aagaaagaga atatatgtta caagagttga gaaacataag aaatataaag
    25681 gtctatgata cagatgctaa ttttatcttg ataaaaatat ataaaaaaac aactaaagaa
    25741 ttgaaaaaag atttgtttaa gcaaggaaac atattagtta gagatgcgtc taattttata
    25801 ggattagatg atagttttat aagagtggct ataaaatctc atgaagataa caaaattctt
    25861 atagaaaata tgaaaaattt attgggtgat taaaatgaaa tcttatggaa tatgcccagc
    25921 atcttgtgga gaatttgtac aaggtataat tgatgatgaa gaatatttat gttcatatgc
    25981 aatagatatg tattctaaag tgtatattga agaaaaatta gtagatataa atttagggag
    26041 atataagtca aggttagcaa ttgaaaaggt atttgaaaaa tttaatttac ctaaaaaata
    26101 tactaaaaat atttctttaa atataaatag taaaatacct gttggaaaag gaatggcaag
    26161 ttcaactgct gatataggag ctactataaa ggcaacatta tcattgatag ataaagattt
    26221 aagtagcgag gagatttcta aattagcagc agaaatagaa ccaacagatt ctatatttat
    26281 agataaaaat agtatattta atcctctaaa tggaactgtt ataaaatacc taggaaatct
    26341 gaccaatgcg aaagttgtaa tacttgaacc aaacaaagta ctagatacta tgaaaattag
    26401 attgaggcaa gattataata aattaaaagt agagaataaa gaagtaataa aaaaatcatt
    26461 tgctctttta gaagaaggat tgaaaaaaaa taatttatct ctagttggag aggcttgtac
    26521 tttgagtagc ttagcaaatg agaatataga aaaaaaagag tatttaaatg aaataataaa
    26581 aatatcaaaa aaatatggag catatggagt aaatattgct cacagtggaa ctgtagtagg
    26641 tattttaatt gataagttta tgaatgataa aaagatgata gatgccttat gtgaatctaa
    26701 cataaattct gtctataata aaatttatac acaaaacata attaatggag gaattaaggg
    26761 ggaaatagaa tggaatacat aaagaatcct atgaaaatag aagaaaaaag ttttgaattg
    26821 atacaagaaa taatagacga aattagacca gattataaat ttaagaataa tatcgaagaa
    26881 aaaataataa aaagagctat acatactact gctgattttg attacttaga tatattaaaa
    26941 atatcagaag aagcagttga tagtataata gatgcattaa aaaataatgc aagtatttat
    27001 actgatacaa atatggctct tagtggtata aataaaagaa agttagaatc attaggatgt
    27061 aagtataaat gtttagtggc agatgatgaa actgtaaaat tagctaaaga aaaaggaatt
    27121 actcgttcta tggcagcagt agaaattgca gctaaagaag aaggaagaaa aatattcgtt
    27181 ttaggtaatg ctccaacagc tttatataaa gttatggaga tgaaatcaga aggtagatta
    27241 gatttagatg cagttatagg agttcctgta ggttttgtag gagcacaaga atcaaaagat
    27301 gaagttgaaa aaacagatat accatatata atttctaaag gtagaaaagg tggcagtaat
    27361 ttagcagcag caatagtaaa tgctatatta tatactatgt aggtacctat atggaagaat
    27421 atgtatatat agatggaaaa aaatatagaa gaggatatac tacaggttca tgtgcaacag
    27481 gtgcatctaa ggctgctgta tatatgttga ttacaaaaaa tagaattaat actataaata
    27541 tagatactcc taaggggata ccattactac taaaagttga taatataaat atttctgata
    27601 catttgtgga atgttccata aaaaaagatg gtggagatga tatagatgca actcatacca
    27661 tggatattta tgcaagagct gaaattgtag ctaaaaatga taagaacaaa gggtatctta
    27721 ctctaaagga tatagatagt ttaagcacca atagtgagtg taaaagtgag ctctataagt
    27781 ttattagggt ttatggcgga actggtattg gtgtggttac gaaaaaaggg cttagtgtgg
    27841 atgttggtaa gcctgctata aatccgactc cacttaaaat gataaatcat gaaataagaa
    27901 agcttatagg agataatttt gaatctatac ttggaaatga taaagtttta aaaataacaa
    27961 tctttgctcc acaaggagaa actgtagcaa aaaaaacatt taatccaaga ttaggtatag
    28021 ttggaggaat atctataata ggtacaactg ggattgttga acccatgagt gatgatggtt
    28081 ggaagaagtc tctatctata gaacttcaga tgaaaaaaga acaaggctta gataaaataa
    28141 tattggttcc aggaaatcat ggagaacagt ttataagaga aaaattaaac ttagatatta
    28201 agtatgtagt tagggtaagt aattttatag gctatatgat taaagaagct caaagaatag
    28261 gatataaaaa aatcttaatg gcaggccata taggtaaatt tataaaagta tctgctggta
    28321 tttttaatac tcatagtaag gtagcagatg ctagaagtga gatattagtg gcaaacttag
    28381 ctttaatggg agctagatac gaatttttaa ataaaataaa tcaatgcgta actactgaag
    28441 aagctgtaga gctaataaat aatagtgaat atagagaagt atataatata ttaagtaata
    28501 aatgtaggga gagagtaaag caatacttga atgaagattc agatgatatt gatgtggaag
    28561 taatcatatt ttcaatggat aagtctttat taggtaaatc ggataataca gatgatttag
    28621 tggaggtctt tatatgataa acataatagg tctaggacct ggtaacttag actatataac
    28681 aaaaaaaggt gaaaatttaa tttccacttc tgatgtatta attggtggta aaagaaattt
    28741 agagtctata aaaaattttg aaggagaaaa aatagttctg gattctaatt taagagaaat
    28801 tatagagtac ataaataaca ataaagaaaa gcaaatatca ataatagcat ctggggaccc
    28861 attaatatat gggataggta gatatctatc taaaaatatt gataataaga tgttaaacat
    28921 ggtttctggg attagttcat tacagtacat attttcaaaa atatatgtag atatgaatga
    28981 tgtatatatt acaagtagtc atggcaaagt accagatttt gattacatat tatcacataa
    29041 aaaagtatgt atggttacag attcaaagat aggaccaaaa caaataagta gagaaataat
    29101 agatagaaat ctaaataaaa ttattgttgt aggagaaaat ctgtcatatg acaatgaaaa
    29161 aataacaata gcaaaaccag aagagataat aagaatggac aattttgata tgaatgttgt
    29221 ggtgatttta gatgaggaat agtgaattta taacaggtaa agttccaatt actaaggaag
    29281 aggttagagc aatatcaata agtaagttaa atttagtaaa tgctaaaaac ctcatagaca
    29341 taggggctgg tacaggaagt gtaagtgttg aagctgcata taattatcct aatttaaagg
    29401 ttatatctat agagaaaaat gatgatgcta tagagcttat agagaaaaat aaaaaaaaat
    29461 tcaacttaaa aaatatagaa gtgataaaag gatatgctcc aattaatcta gggttaaatg
    29521 ttaaagttga gtctattttt cttgggggaa caggaaataa tctggaagaa ataatagaat
    29581 ggtctaaaaa aaatctcgtt acaggaggaa gacttgtagc taattttata ataatagata
    29641 catttaatca aactttaaaa ctgcttaaaa agcatggatt taaagaaata gatgtatgtg
    29701 ttttgaatgt ttctaaacta gagaaactag gaaaaggtga atattttaaa ccactaaatc
    29761 ctatatatat aatatcttgt gaaaaagggg aaaatgatga tgaataaagt acattttgta
    29821 ggagcaggac ctggagataa agagctgata acattaaaag gatacaaatt attaagtaat
    29881 gcagatgtag tgatatatgc aggttcactt gttaatcctg aacttttgga atactgtaaa
    29941 gaagattgcc aaatacataa tagtgcacat atggatttac aagagataat agatgttatg
    30001 agagaaggta tagaaaataa taaatctgtt gtaagactgc aaacaggtga tttttctata
    30061 tatggttcaa ttagagaaca agtggaagat ttaaataaat tgaatataga ttatgactgt
    30121 actccaggag taagttcttt tttaggggca gcatcatctt taggggttga atatacagtt
    30181 ccagaaattt ctcaaagtgt aattataaca agaatggaag gcagaactcc ggttccagag
    30241 aaagaatcaa tacaatcata tgctaagcat cagacatcta tggtaatatt tttatctgtt
    30301 caagaaattg agaaagttgt gtctaaatta ctggaaggtg gatatccaaa agatactcct
    30361 atagcagtta tatacaaagc aacttgggca gatgaaaaaa tagttaaagg aactttaagt
    30421 gatatagctg taaaagttaa agaaaacaac ataaataaga ctgctttaat aatggttggg
    30481 agatttttag gagaagagta taataattca aagttatatg ataaggattt caaacatgaa
    30541 tatagagggt aatattgcta taatctgtat tacagaaaat ggaaaaaaat tagctctaaa
    30601 gataaattct ctagtaaata actgtgttat atatcatgta aaaaataaaa aaagtaattt
    30661 agttgttgaa gaaacatgtg tgcatacagt tcaaaagaag ttaagtgatt ttgtaggaga
    30721 aatatttagc aaatttgatt acatagtatt tataatggct acaggtatag ttgtacgaag
    30781 tatagcacca tacataataa gtaagtttag tgaccctgca attttggtaa tggatgaaaa
    30841 aggcaaaaac gtaataagtt tattgagtgg tcatattgga ggggcaaaca gcttgacaca
    30901 gtacataagt agtcttattg atgctaatcc agtaataaca acagctactg atataaatca
    30961 aaaagcttcc ttagatatga tagcaaaaaa actaaatgca catattgata attttagaga
    31021 aagtgtaaaa gaagtaaatt ctatgctagt gaataataaa tgtgttggat tatatattga
    31081 tgaaggatat caagttgata ctaggggatt taaacttata gaaagtaagg atgagttaag
    31141 agatagtttt tcaaacacat atatagaaaa attagttgta gtaagcaata aaataaattg
    31201 tattgaagat attgagaatt taaacctaga taataaattt gaacattgct atagtaccaa
    31261 aaaaataata aaggtaattc caagagatat agtgatagga attggttgta gaagaaacac
    31321 agatagtgaa ctgatgtata attcacttga agagtttctt aataaacaaa atatagatat
    31381 tagagcaata aacacagttg gaagtataga actgaaaaaa gacgaaaaag caataattga
    31441 attatcaaaa atattgaagg tgccatttaa aacattttca gtagatgaaa tatctaaggt
    31501 tgataatctt tttgataaat ctgattttgt taaaaaaaat gtgggcgtgt attcagtagc
    31561 agaacctgta gcatatcttt tgagcaaagg taatttgtta gttgaaaaac ataaatataa
    31621 aggaataact ttttcagtgg ggagaataaa aatatgatat acgttgtagg aattggacca
    31681 ggaagtaaag atacaatgac tttagaagca ataaaagcaa tagaagattc tgaggctatt
    31741 gttggatata agacttatat aaaactaata gaagaattta tacaagataa agaaataatc
    31801 caaaatggta tgaggcaaga agttgataga tgtaaacaag cagtagagga agcaaaaaaa
    31861 ggaaaaaaag tagcagttgt aagcagtggt gatgctggaa tatatgggat ggcaggtctt
    31921 attttagaat taatatctaa agaagatgaa gatataaaag taaaggtaat tccaggtgtt
    31981 actgcaagta ttggtgcagc agctatactt ggagctccta ttatgcatga tttctgtcat
    32041 ataagtttga gtgatttaat gactccgtgg gaagtaattg aaaaaagatt gagattggcc
    32101 gctgaagccg attttgtaat ttgtttgtat aatccaagaa gtaagggaag aagtgaacat
    32161 ctaagcaaag catttaaaat aatgggtgag tttaaaggtg gagatacacc tgttggagtg
    32221 gtaaaagatg taggtagaga aaaagaagaa aagtttgtat gtacttttga aaatatggac
    32281 tttgaaaaag tcgatatgac tacaatggtt ataataggaa ataagtctac ctatattaat
    32341 ggtgaattga tgataactcc aagaggttat acagtatgat tttaatttta ggaggaactt
    32401 cagatagttt atctatatgt gataagataa atgaactgaa aaatcaacca tatatccttt
    32461 cagttactac agattatgga agggaacttg cacaacaaca tgcagagaat gtaattttag
    32521 gtaagcttgg aaaagaagat atgctaaaat ttataaaaga taataatata gtaaaaataa
    32581 tagatgccac tcatccttat gcagttgaag tatccaaaac tgctattact tgtgcaaaac
    32641 tattgaatat agattatata aggtttgaga gaaaatcttt aattgaagaa atagattatg
    32701 ataataaatt tatagtagat acaattgaag aagcctgtga aatagcaaat aaaataggga
    32761 caaatatatt cataggaaca ggaagtaaaa atttgaacag atttatagag gaaataagtg
    32821 ataaaaattt agttgttaga gttcttccaa cgagtgaagt catattaagt tgtgaaaaat
    32881 taggtttaag tgcagataat atagtagcta tgaaaggtcc atttagccag tatataaatg
    32941 aagaaacata taaacattac aatatagatt tagtcataac aaaagaaagt ggaatagctg
    33001 gtgggttctt agagaaggta aatgcatgta aaactttcaa tataccagta ataattataa
    33061 aaagagaatc gattaactac gaaaatgtat ttaatgacat aaataaaatt aaagacatac
    33121 ttgtgtaatt tttaggagga gaatatatga agaaagcctt attagtagtg agttttggta
    33181 caagctatca tgaaacgaga gaaaagacaa tagatatatg tgaagataaa ataaaaaatt
    33241 cgttaaaaag ccatgatttt tttagagctt atacatcaaa tatgataata aataaaataa
    33301 aaaaaaggga tggaatagaa atagataatc caatacaggc tttagataaa atatatgaac
    33361 aaggatatga tgaagtaata atccaaacac ttcatattat atgtggcgaa gaatttaaca
    33421 aattaaaaga acaagtagat ggatattctt ctaaattcaa aaagattgta ttaggaagac
    33481 ctttgcttac acatattgaa gattatcagg aagctgtaga ggcaattaag catcaaattc
    33541 ctcatatgga aagtaatgaa gcagtagtat ttatgggaca tggaacactt catgaatcac
    33601 attcagcgta tccagcattg gaatacatgc ttagggataa tggaataaat gcttatgttg
    33661 gtacagttga agggtatcca gaaatagaac atgtaataag aagattaaaa gaaggaaata
    33721 taaaaactgt aaatttgatg ccatttatgt tagttgcagg agaccatgct ataaatgata
    33781 tggcaggaga tgaagaagat tcttggaaaa caatattaga agaaaatgga tttaacgtaa
    33841 gagttcattt aaaaggacta ggagaaaatt cttatataca agataaattt gttcgtcatg
    33901 ctgtaaaatg tgcagagaat gcgaagttct atggtatagg agcagggcca ggagatggtt
    33961 ctttacttac gataaaagcg gttaatactt taaagaaact ggatattcta tacactccag
    34021 aatcaaaaaa gggtggagat agtctagctt tatcaatagt tagtgaatat ttacctgaat
    34081 cagtggaaat aaagtctagg catttcccaa tgagttttga tgggaatgaa aaaagtttag
    34141 cttgggacaa tgtggcacaa gaaattatat cagatgttaa tgatggtaaa aatgtaggat
    34201 ttgttacatt aggagaccct atgatttata gtacatatgt atatataatg aaaagaatat
    34261 taggagaggt agaagtcgaa actataccag gaatttcatc attttccaat atagcatcta
    34321 atcagaattt tccattagtc atggataaag aagctttagt ggtaattcct tgtactatgg
    34381 aagatgataa gatagagtat gctttgcaaa attataattc aatagtattg atgaaagtat
    34441 ataaaaattt taaagaaata ataaaaaaat tagaaaagta tgatttaata gaacatgcta
    34501 ttttagtaag taattcttcc caagaaagcg aaaatgtgtt tacagattta aaagaagcgc
    34561 accttgaaga taagatatct tatttttcta ctatactagt aaataaagat aataaaataa
    34621 aataggtgaa agcaatattt aaaggagact taatatgaat atagtggttg gaactagggg
    34681 tagtaatcta gcgcttatac aaacagaatg ggtaataaat gaattaaaaa agaagtatcc
    34741 agaaattagt tttgagatta aaatcataaa gacaaaagga gatttaattc aaaatgtttc
    34801 actggataaa ataggtgata aaggattgtt tgtcaaagaa atagagcaac aattattaga
    34861 tggaaaaata gacatagcag tacatagtat gaaagatatg ccttcttatt tagcagatgg
    34921 actaaaattt gctcatacgc ctaagagaga agacccaaga gatgttctaa tacttagaga
    34981 aggatataaa aatttagatg atttacctca tggagcagta ataggaacag gaagtaaaag
    35041 aaggaagttt caattattga aacaaagacc tgatttaaat atagtacaag ttagaggtaa
    35101 tgtggaaact aggatacgaa aaataaaaga tgaaaacatg catggtattg tgttggcagc
    35161 atcaggaata attagagcta atttgcaaga taaaataagt tcttatttac ctgttgatgt
    35221 tgttattcca gcacctgccc aaggagcttt agctatagaa attagaagca atgatagtgc
    35281 gatagaggga atagtaaatt cactgaagga tgagaataca gaaatccaaa tattggctga
    35341 aagaggtttt ttagatggtg taaatggaag ttgtcatatt ccaatggcag cttattgtga
    35401 aataatccaa gataaaatac atcttactgg cttatatgga gattcagaag gaaaaaaagt
    35461 agtaatcaag tctatagatg gagatatttc ttctcctaga gagttaggtt taaagttagc
    35521 taaacttgta ttgaaggagt atgagaatta tgaagggtaa ggtttactta gtaggggcag
    35581 gaccaggtga ttataaactc atgactttaa aaggtttaga gtgtataaga aaatcggatg
    35641 taatagtata tgatagatta gcaaatagta gttatttaag agaagctaag cctgattgtg
    35701 aacttatata tgtaggcaag gcatcaagta atcatatttt gccacaagaa gatataaata
    35761 gaattatagc agaaaaagct aaagaaggaa aaattgtaac tcgtcttaaa ggaggagacc
    35821 cttatgtatt tggcagaggg ggagaagaag cagagacttt agtagatgaa ggtatagaat
    35881 ttgaagtagt tccaggtata acttctgcta taggaggttt atgttatgcg ggtattccta
    35941 taacacatag agaccatgct tcgtcatttc atgtaataac aggtcatttg aagggtgatg
    36001 atagtggaga actaaactgg aatgctcttg caaataacaa aggtactctt gtgtttttga
    36061 tgggaatttc aaacctagag aaaataagtg aaaacttaat gaaagaagga aaagataagg
    36121 atacacctgt tgctcttata agttgggcaa ctagatataa tcaaagagtt gttacatcta
    36181 cacttgaaaa tgtttatgaa actgctatta aagaagaagt aaaaccgcca actcttatag
    36241 tagttgggag tgttgtagga cttagagaaa agttgaactt ctttgaaagt aagcctttat
    36301 ttggaaaaag tattgctgta actaggtcta gaaatcaaaa tagtgtattg gtagaaaaaa
    36361 taatggattt aggtggaaat cctatagaaa tacctactat taaggtagaa aaaatacaaa
    36421 ataatattaa cttagaaaat gaaataaaaa atataaataa gtataattat ctaatactaa
    36481 ctagtaaaaa tgccgtagaa atcttctttg aaaagatata tgaaatgaat tttgatttaa
    36541 ggatattatc taatttaaag gtatgtgcta taggttctgc tacatcaaat gagttgaaaa
    36601 aaagaggaat tatagcggat atagtaccaa aaaaatttgt agcagagtca ctgtatgaag
    36661 agttagcgcc tattttaaat gatgacgata atatacttat acctagagca gaaaatgcta
    36721 gagattatct ggttgacaaa cttaaggcta tttgtgaagt aacagaagta catatatata
    36781 gaacagtaat agatgaggag aaaaaaggtg agatattaga tattttaaat tctaatgaca
    36841 tagattatat aacatttact agttcctcaa cagtaaataa tcttgttgaa attataggaa
    36901 aagaaaatat taaaatatta gaaaaaataa aaacactatc tataggtcct ataactacag
    36961 agacaataaa tagtttggga ataaaattgt acaaagaatc tgctacatct actatagatt
    37021 cgttagtaga tttaattata aaaaattaat tttggaggct tgaatatgtt aagaagacca
    37081 agaagactaa gagcaagtaa agcaatcaga aatttggtaa gagaaactaa ggtgaatgta
    37141 gaagacttaa tatatccact gtttgtagta gagggggaaa atataaaaga agaaattaaa
    37201 tctttaccag atgtctatca tttatcaata gatatgctag aagacgaaat aaaagaaata
    37261 agtgagttgg gaattgaaca tataatgtta tttggtgttc cagatgaaaa agatgagtgt
    37321 gcttcacaag cttttaatga taatggaata gttcaaaagg caattagaaa ggtaaaagaa
    37381 ataaattcag atataaatgt aataacagat gtctgtatgt gccaatatac aagtcatgga
    37441 cattgtggga ttttaactga tactggttat gttgataatg ataaatcatt ggagtatttg
    37501 gctaaaatat ctgtaagcca tgctaaagca ggagctgata tggttgctcc atctgatatg
    37561 atggatggaa gaatacaagc aataagagaa gctttagatg aaaatggatt agaaaatgtt
    37621 ggaatcatgg cttatagtgt taagtatgct tcaaattatt atggaccttt tagagaggca
    37681 gctcattcag caccatcttt tggagataga aaaacatatc aaatggaccc agcaaatagc
    37741 aatgaagcta taatagagac tgaacttgat atattggaag gtgcagatat acttatggtt
    37801 aaacctgcat tatcatattt agatattata agaagagtta aagataattt tgacttacct
    37861 ctagcagctt ataatgtaag tggagaatac tctatgctta agtttgctgt gaaggaaggt
    37921 ttattaaatg aagatgtaat tcttgaatca attacatcta taaaaagagc aggagcagat
    37981 ataataataa cttattttgc taaagacatt gctaaactgt tgaaaaaata aattctagca
    38041 gtataaagaa tatcaaaaag tataggaatt gtaattaact attatacagt agttttgttt
    38101 agacatttat tgaagaataa tagaaactaa tttgcaattt ctatacttta tttatgtaac
    38161 taaataaaat ttggaggtag aagatgctat atcctattaa tttaaaatta gatgagttag
    38221 atgtagttat aattggtggt ggagaagttg catataggaa atgtaaaaat tttttagagt
    38281 ttaacaaaaa tgttactata gtttctaaac aaattttaaa taaattttat gatttaaaag
    38341 gaaatataaa aataataaaa gatgattata aagaaatata tataaaagat gcttctgtaa
    38401 taattgctgc cacaaataat agagagttaa atatggaaat aggattatat tgtaaagcaa
    38461 aaaataagct agtgaatgta gttgataata tagaaatatc gaactttact gttccatcat
    38521 atataaaaag aggagattta cttataagtg tgtctactgg gggcaagagt ccttcattat
    38581 catcaaagat aaaaaaagaa attgaagaga gatatactga agattatgag gagtatttaa
    38641 atgtattagg agatataaga aaaaaggtta taaaaaaata cgaagataaa agtaaaagaa
    38701 aagatgtgct taatatgttg gtaacacttg acctagaaga acttaagaag tttgatatat
    38761 aaaaaataaa ataaaaaatg ttaaaaaggt gttgacggat tatttttaag atgatatagt
    38821 attacttgtc cttaagaaaa gggcaaacat aa
//
LOCUS       DAEPHU010000035        38770 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 01A10CD0081
            SAMN05941466-rid12468953.denovo.035, whole genome shotgun sequence.
ACCESSION   DAEPHU010000035 DAEPHU010000000
VERSION     DAEPHU010000035.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941466
            Sequence Read Archive: SRR6291087
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 38770)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 38770)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068158.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 22:43:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,892
            CDSs (total)                      :: 3,805
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 87
            rRNAs                             :: 8, 1, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 55
            CDSs (without protein)            :: 55
            Pseudo Genes (ambiguous residues) :: 0 of 55
            Pseudo Genes (frameshifted)       :: 21 of 55
            Pseudo Genes (incomplete)         :: 28 of 55
            Pseudo Genes (internal stop)      :: 16 of 55
            Pseudo Genes (multiple problems)  :: 8 of 55
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..38770
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941466-rid12468953.denovo.035"
                     /strain="01A10CD0081"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            144..686
                     /locus_tag="KR231_001899"
     CDS             144..686
                     /locus_tag="KR231_001899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HBH0004276.1"
                     /translation="MKICITVGHSILKGGKSTGVNGIVDEYNYNKKLAPMLAEMLISQ
                     GNTVDVIICPERHFMSEREEFFYRVPKVNSGKYDLLVELHLNKADGTQCGTEVLYYGT
                     EGLEYAKRVSNRLGELFENRGAKKRENLYILRNTNPVAIQIESFFCDNVNDCNKANES
                     GYDYIARLITEGILNKDINM"
     gene            1014..2507
                     /locus_tag="KR231_001900"
     CDS             1014..2507
                     /locus_tag="KR231_001900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HBH0004277.1"
                     /translation="MKYTFEKFKLNEKILKSLKSLGYNIPSRVQREVIPKLLKGQNLV
                     VRSKTGSGKTASFAIPLCENINVDYNNIQALIVVPTRELALQVKDEISDIGRLKKVRC
                     SAIFGKQSIKDQIAELKQRVHIVVATPGRILDHINRGSIKLENVKYLVIDEADKMFNK
                     GFVEQMEKILLNLPKEKIVSLFSATIDEEIKYICEKYMLDYSVINIEENESDTNQKTR
                     QIDDKIIKANGREKYILLKELIYSENPKSVIIFCNTKEKVSKLYNKMSKEGFLIRELH
                     ADLSQERRIFVIKDFKNQKFNVLVSSDVASRGIHIDDISLVINYDVPQDKENYIHRIG
                     RTGRKGNSGKAITIVTEKDEKYIENIETYIGYKINELKDIEKSRITHGKILFEEYSKG
                     ILKKVSKRKKVDKNSYNSKDIKLNIESEVVKLYLNAGKKKKIRVLDIVGAFSNIKGIT
                     NDDIGVIEVQDLCSYVDILNYKGDLILKKYKEIPIKKKMVKVKRDIR"
     gene            2581..2814
                     /locus_tag="KR231_001901"
     CDS             2581..2814
                     /locus_tag="KR231_001901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0004278.1"
                     /translation="MKAEDMKRKVSPIDLERILVTGGVIKHEDSIWLLDFWGNKDIAG
                     ILLMPPTRHVILHLNDCCKWKEYFRTKKKFYRS"
     gene            2970..3734
                     /locus_tag="KR231_001902"
     CDS             2970..3734
                     /locus_tag="KR231_001902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HBH0004279.1"
                     /translation="MAYFNYNDKQCYYNEIGDGTPLLFLHGNTASSKMFNDIIDFYKD
                     EYKVILIDFVGHGKSQMVDKFSADLWFDEAMQVICFLEAMNYKKVNIIGSSGGALVAL
                     NVALERPDLVNKVIADSFEGEVPLESFVQNVKIEREASKQDDGAKAFYIYNQGENWEK
                     VVDNDTEAIFEHYKTIGKFFHKPLETMQPEVLLTGSREDEFVSLISSDFFENTFSLLL
                     EKIKNGKMYLFDKGGHPAILSNGLDFSNVAKKFLEE"
     gene            complement(4019..7198)
                     /locus_tag="KR231_001903"
     CDS             complement(4019..7198)
                     /locus_tag="KR231_001903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HBH0004280.1"
                     /translation="MKIDMIYKLIRRNTEPSRWSRGVKYYTNQLVDYIDIDIDDLQNN
                     LLTFRGGVNSEDNYSFYFNSITIDIKHFKIIENDCSCADCQSKGKSIFICKHIVAIVI
                     KSLKQIKNKKDVPPILIDILGADKDKLSNTNSKTSLDLSKQLLSLLDNTKRERVNLDV
                     LINVDSNKAIAEFKIGIDKMYILKNITEFAYSKLNGYELDFGKKFTYNPNTHYFADED
                     EKLVDIIEEYGTNLSYNFSSSHSKKFMEINASSLKQFLNAIKYKDFTLIFSKEEYHPK
                     ILNDTLPVRFDFKNIEDKIVLYSKDSLPVPLTKKNDVLLYDGNIYLLSHKKAHDYSKI
                     YQILSKTKELKFDKEDSKDVLGLLVPRLKSISQEVHLDDNIKNNITKDFKSEFYFDMI
                     DGNICCDVKYIYDDEDKKFVLPNIQKEATIENKLTSSQFTKENNHYVFKGTDHDLFTF
                     LDLQLESLKEFGDIYYSEKFKLKKIYNASSIQASINQTNQNYLEFNFNISDINPREYK
                     DILKAFQEKRTFYKLKDGNFIDLSERETKDFFELVENLDIMDKSKNNKIHKNKALYIN
                     DVIRSKNLKFIDGKKELDSICEKFRNFDSINLEIPANLNANLRDYQINGLNWFKVLDY
                     YKFGGILADEMGLGKTIQTIAFLLSLSNKKSLIVTPTSLIYNWKNEFEKFAPDIKVLL
                     IHGNKRDREKCFMELENFDVILTTYGTLRNDLEKYSEIKFDYCILDEAQNIKNPVALV
                     TESVKSINAENKFALTGTPMENNLLELWSIFDFIMPGYLYSKAKFQELFINKEDNVKN
                     LKKLIKPFILRRSKKQVMKELPDKIEKNFFVELNKEQKKIYSVYSKDIQDKMKDKNLK
                     KDKIVIFSYLTKLRQLCLDPSIVVKDYNKKSSKIETCLEILRDSINENHKILLFSQFT
                     SVLKNISKELDKYKIKYHYIDGKTNAKERLELVDEFNNSMDKKVFLISLKAGGTGLNL
                     TSADMVIHFDPWWNPSVENQASDRAHRFGQKNSVQVIKLIAKGTIEEKIIKLQESKKE
                     LINQFINGELSNEGVLKSLSDEEIINLFN"
     gene            7479..9656
                     /locus_tag="KR231_001904"
     CDS             7479..9656
                     /locus_tag="KR231_001904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdopterin-dependent oxidoreductase"
                     /protein_id="HBH0004281.1"
                     /translation="MYNKYNNLYLLLGKENVNMDSYRQLKAKIPCKETGIEIKRTLCD
                     ICSPGVHCGIDAYVKDGKVIKIEGTKEHPMNKGLLCTKGLCNREYIYREDRIKTPLKR
                     IGKRGEGKFKPISWDEAYREIAEKLNRVKSEYGAKHVAFFTGYGKWYRPFLQRFASSF
                     GSPNYGTESSSCSTSAQMAGNVATGRNFTMQDMENAKTYLGWGFNPYYSKFLNSVNLI
                     KLKEKGLKFIIVDPRITPTTQKLADLHLRIKPGTDGALALGMANLFIQKDLIDREYIE
                     KHVHGFNEYKEYVKLFDLDTVSRITGVSKDNIVKAVEMLSQGPFCINESAAPIVHHQN
                     GFQNYRAMMSLSAITGNYDRIGGNIPKQDYFAGKIGGFQTLEKEFVKEVLPKNINERI
                     GGERFPLWNEMVTQFQAMDLPRQIEEKTPYEIRALFCHGINARMFTNSGRLFKALNSV
                     DFFVNIDLFMTDTSKYADILLPACTSFEREECKSYPGGYITYTKKVIDKLYDSKSDVE
                     ILSDLANAMNIDDDLLKAGYEASIRHMFKNTCVDVDKLKESDLPLKCKDFKPYIVGSY
                     TREGYDTSTSRFELKSTIIEKYKDFGLDALPTYRGFNDNIDDEYTHLLTSGARISNAL
                     HSRLHDIKLSRILKNEASCDISSLDAKELGVISGDYIKITTKIGSLDVKVNVTDRVLY
                     KNIHMYHGYREADINSIICDNFDPYSGFPAYRSCKCKIEKMNR"
     gene            9670..10092
                     /locus_tag="KR231_001905"
     CDS             9670..10092
                     /locus_tag="KR231_001905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S binding protein"
                     /protein_id="HBH0004282.1"
                     /translation="MKSLFKFNKELCTACGACLLACIDQNDNNIDNGELFRHVFTIEE
                     GENIEYFSLACIHCNEPKCLGVCPKNCFKKEEGFIVLDNQNCIGCKLCEKACEYGALI
                     YGNDGKANKCNGCIERYKCGMDSPCVMVCPTGALKFNK"
     gene            10500..11303
                     /locus_tag="KR231_001906"
     CDS             10500..11303
                     /locus_tag="KR231_001906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HBH0004283.1"
                     /translation="MKKLKLIIMFALVSALLVTGCSSGNNKNKEEQKVIRVATSGTYY
                     PFAFKDKDKLKGFEVDFWDEFAKRTNCKVEWVLTDFSGLFGLLEADKADVVSAQLTAT
                     PEREKKYAFSDAYNYSGTNIIVREDDTSIKSIDDLVGKKVGVGTGAVANEILKEKYPN
                     DEIKIVNYSSATLKGNYQDLEMGRLDAVVAQDVEALIAIKEQKLNLKMIEPPIQFGAC
                     SFALQKNEKGEKWTKEINEVIEEMYKDGTLTKISENWLGKDITKEPINE"
     gene            11296..11964
                     /locus_tag="KR231_001907"
     CDS             11296..11964
                     /locus_tag="KR231_001907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HBH0004284.1"
                     /translation="MSNFNFEFCLSIFPFLIKALGITILISIVAFFLSILLGVILAFF
                     TQTKSKVLQYITRVYVSFFRGTPLLIQIFFFYFGFPMIFSFMKDCSPYLAIVICLGVN
                     SSAYMAEIIRASIESVDKGQQEACYAFGLSKYQSMVKIILPQAATSAVPPIVSCTLDI
                     IKGSSLGLTIGIQDLMGVAQVEAASSFKYFEIYMITILIYWAVSIILSNIQSKVEKRI
                     RRAY"
     gene            12200..12862
                     /locus_tag="KR231_001908"
     CDS             12200..12862
                     /locus_tag="KR231_001908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HBH0004285.1"
                     /translation="MAFNMKYFLELFPTIMKSFNVTVILAISSLVFSLIIGTIVALSS
                     YYKVKVLNQICKVYVSIFRGTPLMPQLFFLYFGLAYMSDFVKNMDPVFATSIVLSLNM
                     GAYMSETIRASILSIDTGQIEAAYAMGLTNLQTMKRIVIPQAVRVALPSLFNNFIDLI
                     KGSSVAFVVGVNDIMGAAKSQGALSFKFFEVYGAVMVIYWCIITPLGWGQKKLEKKIS
                     NY"
     gene            12922..13719
                     /locus_tag="KR231_001909"
     CDS             12922..13719
                     /locus_tag="KR231_001909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HBH0004286.1"
                     /translation="MIKRNIIKCLVAVLSLTFVITGCSKKEEVKNEKVITVASSNSAD
                     PYSYVDNGEHKGFEVDMWKEIGKRSGYKIKMEPTGFSSIFGMLDSGKVDVAANFFGMS
                     KERLEKYDASIPYGSDSVCIAVKDGNNEINKLEDLKGKVVAVSEGSQGQQVATSVNKD
                     NLFQEKVYGDGTSGLQDLDLGRVSAWIDAELTIVGDAKKANMKVRVLDKKLSATNIAY
                     FFKKNDDKSKTIKEDVNKAIEEMLADGTVKKISEKWFGMDVSADIQK"
     gene            13837..15027
                     /locus_tag="KR231_001910"
     CDS             13837..15027
                     /locus_tag="KR231_001910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433937.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HBH0004287.1"
                     /translation="MEVLQMIETKIKSIALKNREKIIKIRRQIHSNPELAFKEYKTSK
                     LIKEELNKLNIEYINIAGTGVLATIKGKNNGGKTILLRADMDALPIKEENDLEFKSIN
                     DNMHACGHDAHVSWLLGTAMILNDIKEELNGNVKLLFQPGEEKGGSDIVIKENVLEGV
                     DALATGHCWPTIESGKIGIARNCAMAATNTFEITIIGKGGHGAEPHNCIDPIAVGNAV
                     YSSIQQIVSRKIDPVVPVVVSVCSFNSGVSKNIIPDVCTLQGTIRAISKEQVIEVSKI
                     LEYIVKNVCKAHGADCKFEKSTGGDAVINDKNMIEIGRESACKILGAENVEIIDFPAM
                     TGEDFAIYMKEKPGLFMYIGVGDKEKNINYRLHSNKFNIDEKCLSIAPSLFSQLTVDY
                     LCQL"
     gene            15136..15885
                     /locus_tag="KR231_001911"
     CDS             15136..15885
                     /locus_tag="KR231_001911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HBH0004288.1"
                     /translation="MIKVENLHKSFKGTEVLKGINLEISQSEVVAILGSSGTGKSTLL
                     RCLNYLVEPTKGKIMIGDVKVDVEKATKKDITNLRKHTSMVFQNYNLFKNKTALENVM
                     EALIVVHKKSKKEAREISLKLIDKVGMLDRKDFYPSKLSGGQQQRIGIARAMAVNPNV
                     ILFDEPTSALDPELVGEVLSVIKSLAKEGITMLIVTHEINFAKEVADKIIFMDNGVIA
                     EEGTPDEIFNNPKNERTAKFLNIIRKEEVFS"
     gene            16476..17537
                     /locus_tag="KR231_001912"
     CDS             16476..17537
                     /locus_tag="KR231_001912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dicarboxylate/amino acid:cation symporter"
                     /protein_id="HBH0004289.1"
                     /translation="MRDFLKNYKSSIILLACTIVGAIVGLVLGPKASILKPFGDLFIN
                     ALLMIVVPLVFLSVSSGVASIKNMERFGKIMKGTAIVFMGTTLVIAFLGITSALLFNP
                     SKGLDVSSVKNLMVTQDAETLESKGTLLDQVVSSITVKNFGDLFSSSNLLQLVIFAVL
                     IGTAIAMMGDRGNTIRKLLSEGTEAILKVVSIFMLYAPIGLGCYTATIIGELGSKIIQ
                     GYVRVFVIYSLTAAMYFLLFYSLYAFLSAGKQGFRQFWRNAIKPIATALATSSSSACI
                     PSNLEASKNIGVPDDISETVIPLGINIHKDGSVLAVIIKVAFLSGILGSGMANPATIG
                     QLFITVFVVGVFMAPVAGG"
     gene            17550..17747
                     /locus_tag="KR231_001913"
     CDS             17550..17747
                     /locus_tag="KR231_001913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation:dicarboxylase symporter family
                     transporter"
                     /protein_id="HBH0004290.1"
                     /translation="MLVVSIFGFPVEAIPLLTVITTITDIPNTILNTTGNTVSSMLVS
                     RLVEGKDWLIDKTAITTKKIS"
     gene            complement(17911..18615)
                     /locus_tag="KR231_001914"
     CDS             complement(17911..18615)
                     /locus_tag="KR231_001914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HBH0004291.1"
                     /translation="MQQGSDYLKKFLEKHIDLLKKIPLFEGIKSDELEEMLECLGVVD
                     KTYTKDSIIFSVGSEVTSIGIMLKGSAHIIKEDIEGNRNIVAELLPGDLFGEVFACTR
                     LHKSNVTVTTTSSCEVLFIKFKSVTGICSSACVFHNRLVENMLQLIAEKNILLHNKIE
                     LLSRKTTREKLLMYFSKQIEQTGSHQFTIPFSRNEMADFLCVDRSSMSRELGKMRDEG
                     LLSFNKNKFEIFYFKK"
     gene            18780..19505
                     /locus_tag="KR231_001915"
     CDS             18780..19505
                     /locus_tag="KR231_001915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S binding protein"
                     /protein_id="HBH0004292.1"
                     /translation="MMRKIIKIDEEKCNGCGLCVEACHEEAIGMVNGKAKLLRDDYCD
                     GLGDCLPTCPTNAISFEYREAAEYDEAAVKANMEAKKAQKKTLACGCPGSQSKSINRE
                     VSNSMSISNDIVEIKGSQLNQWPVQIKLVPTNASYLKNASLLIAADCTAYAYGNFHNK
                     FMKNKVTLIGCPKLDEVDYAEKLTEILKENDIKNIVVTRMEVPCCGGIVNAVKTALQN
                     SGKMIPWQIVTISVDGKIVDGEI"
     gene            19565..21157
                     /gene="hcp"
                     /locus_tag="KR231_001916"
                     /gene_synonym="priS"
     CDS             19565..21157
                     /gene="hcp"
                     /locus_tag="KR231_001916"
                     /gene_synonym="priS"
                     /EC_number="1.7.99.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxylamine reductase"
                     /protein_id="HBH0004293.1"
                     /translation="MEKMFCFQCEQTAGGKGCTINGVCGKKGGTANLQDELTGVLIGL
                     SRATIGNKNRPTSETDKIMIEGLFTTITNVSFDDEAIKRQIEKTEVEKSKLVPRCSDC
                     STTCNRNDNYDMKDLWNDNEDIRSLKSLILFGLRGMAAYAYHAMVLGYTDKDVNEFFY
                     EGLIAVGGDLSIDELLGLVMKTGEINLKCMELLDRANTETYGTPEPTQVSMKIEKGPF
                     IVVTGHDLYDLHKLLEQTKDKGINIYTHGELLPAHAYPKLKEYKHLKGNFGTAWQNQQ
                     KEFDNIPAPILFTTNCLMPVKDSYRDRVFTTEVVAYPGMVHIDEDKDFSSVIEKALEL
                     GGYREDVHMTGINGGDTLTTGFARGTVSSVQDKVVDAVKSGAIRHFLLVGGCDGAKPG
                     RNYYTEFVKQAPKDTVILTLACGKYRFNDLDLGDICGLPRLMDMGQCNDAYSAIKVAV
                     SLANAFECGVNDLPLSMVLSWYEQKAVCILLTLLHLGIKNIYIGPSLPAFLSKNVLDI
                     LVDKFALTPISTPEEDMKKILG"
     gene            21529..22434
                     /locus_tag="KR231_001917"
     CDS             21529..22434
                     /locus_tag="KR231_001917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="patatin-like phospholipase family protein"
                     /protein_id="HBH0004294.1"
                     /translation="MKNSNFNILAFDGGGLKGALSISILERIVKEYPNLLNNINMFGG
                     TSTGSLIALGLAYGVSPKEIKELYSIENSKYIFNKSYAEILRPKYENKNLKEVLLSIF
                     PEELELKDLNKLVMIPSFYIGNEENAWKPVFYNNMPNSFTKTSKVVDVAMASSAAPVF
                     FPTYNRHVDGGIIATDPSLACIIHAIDSGFKLKNTRLFSIGTGYVYNSIKADTTEWGA
                     IDWIINKEPDLPIISITLEGNSQMSQLFSQKLLGDNYYRLNPKMEKDVAMDDCDALEY
                     LMSLGENCDIKDAFGWIKKKSFYRN"
     gene            22558..23511
                     /gene="msrA"
                     /locus_tag="KR231_001918"
     CDS             22558..23511
                     /gene="msrA"
                     /locus_tag="KR231_001918"
                     /EC_number="1.8.4.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (S)-S-oxide reductase MsrA"
                     /protein_id="HBH0004295.1"
                     /translation="MIKLATFAGGCFWCMVKPFDKYDGVIKVVSGYTGGHVENPTYQE
                     VCSGTTGHLEAIQITYDDDIISYDELLNIFWKQINPTDDGGQFGDRGTQYKTAIFYHD
                     EEQKNIALESREHLENSKIFDSKIVTDIIPATKFYEAEENHQDYYKKRPLNYNMYYKG
                     SGRYNFVKSHWDGNNINREELKKTLTHIQFEVTQNDMTEVPFENEYYDNNKEGIYVDI
                     VSGEVLFSSKDKFDSGCGWPSFSKPVIDKSIIERSDFSQGMYRVEVRSAKGNSHLGHV
                     FDDGPKELGGLRYCINSASLKFIPRENMEALGYGEYLKLFE"
     gene            23664..24794
                     /locus_tag="KR231_001919"
     CDS             23664..24794
                     /locus_tag="KR231_001919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBH0004296.1"
                     /translation="MNLKDFNGKRLKSARIFRAKTIEQLSKETKINKKDLKAFEENKY
                     VPNIENTLKLSNILNFPKEYFYKNENINIVVEDSHFNPQSKLPRVEEISYREKIIIIH
                     KIYSFMENYIKFPKENLPNRKVMSDININDIESLAYKTREFWDLNSTPIVNMVSLLES
                     KGIIISGMNVDRKGATIFTQKQRISKESKYLISLGNDKKSASIRNYTLACELGYIISS
                     ELRIPSKQFSEDEYACAFLLPKESFLKDLTHPEDLDYYVELKKKWIVPISAMIFRAYN
                     LEKINYKKYNYLMNEMDKKGWLIEEPLDKMKGSSPTYLKRAVELLIENKIMSVNSIVS
                     SLEEFGINLYPEDLELLMGLKKGLLSQEVNKKSKVIKFDGKK"
     gene            complement(24911..25879)
                     /locus_tag="KR231_001920"
     CDS             complement(24911..25879)
                     /locus_tag="KR231_001920"
                     /EC_number="1.1.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate dehydrogenase"
                     /protein_id="HBH0004297.1"
                     /translation="MAIKPRKISIVGSGHVGSHCGFSLITQGVCDELFMIDIDESKSK
                     AQALDLADAVSYLPHKVHIEKGTFSDCKDSDIVVISVADSSEGPLRRQNTTRLDLLRP
                     TIGMIKSIVKPIVDSGFDGIFVVISNPVDVVTNYIWEKSGFPKNKVIGTGTALDSTRL
                     RRILSEETGIAQQSIQAYSMGEHGDSQMVPWSHVSIGGKPILDMIKDNPSTYSNLDLP
                     SIVEKNKKTGISIINGKDCTEFGIGTALVEIVKAILHNEKKVLPVSTLLEGQYNERNV
                     FAGVPCVIGKDGIEEIIEINMTEYEQNEFNKSCSVLREYIALSKTL"
     gene            26214..26402
                     /locus_tag="KR231_001921"
     CDS             26214..26402
                     /locus_tag="KR231_001921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0004298.1"
                     /translation="MNYHTKEELVEALRVVSSSIINCGKGQKKFSEETSHHTRFKNII
                     EVMYISKSLIMDEISKRD"
     gene            26662..27861
                     /locus_tag="KR231_001922"
     CDS             26662..27861
                     /locus_tag="KR231_001922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433961.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanyl-tRNA editing protein AlaX-L"
                     /protein_id="HBH0004299.1"
                     /translation="MEKLYYTNQYIRDFTAEIIEIKEVENKYHVLLDKTAFFPGGGGQ
                     FGDLGKIESDDVINVYEDGKKIYHVLDKKPIKIHKVKCSIDWDRREDGMHQHFGQHVL
                     SGCFFKTFNANTTGFHLGNEYSTVDIEGNLEEDKIREIELFANEIIRQNIQVETLLPT
                     KKELKKIWLRRDLPNTDEEIRVIKIGDLDTNACCGVHPKSTGELRMIKIKKWEKHKSS
                     TRIEFLAGKRAVDEVLKRDIYLTKICRYLSCSEEDAINGIVNLNSKVEEALIKKRRLE
                     EVVSTYQVKEMIEKANKVGNISVIKKIYDDEDLKYVNKIANKIAEYENSIALLAVKFN
                     DKINLVFACSKNLKDINMGVLLKDAISLIDGKGGGSKVLAQGGGKNNGNLEATLDYAF
                     MKIEKTL"
     gene            27913..28416
                     /locus_tag="KR231_001923"
     CDS             27913..28416
                     /locus_tag="KR231_001923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBH0004300.1"
                     /translation="MEQQKDYIELYENEELIEIREARMDDLDTIAKFNYNLAKETEGK
                     ELDMDVLTKGVKALLLDERKGKYHVYTVFDKVVAQIMYTYEWSDWRNGNFLWIQSVYV
                     DKEYRRKGIFNYLFNYIKNICDKDENIVGMRLYVEKENINAKATYESLNMYECDYNMY
                     EYEVIHS"
     gene            28523..28840
                     /locus_tag="KR231_001924"
     CDS             28523..28840
                     /locus_tag="KR231_001924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430572.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0004301.1"
                     /translation="MGVLKGMFYVFLFLDLVSIFCFFFNKGKIASNKIVFNAIGVLTF
                     VLCFMLFSYYPNNNLIGKFIASLFFIFGVAGVMLKEKNFLYARLLLTVVIVFSTLRLF
                     VIQ"
     gene            28998..29957
                     /locus_tag="KR231_001925"
     CDS             28998..29957
                     /locus_tag="KR231_001925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HBH0004302.1"
                     /translation="MIESKKSEKLLLSIIYIIFLVYILMIIRIILFRDVPIYAIFKGT
                     FRNVNLIPFYTIYQFIVDSNLDFMKATVNIIENIGIFIPMGIFLPIVCKNLNKKTIII
                     VIILVSLAFELTQYIFALGSSDIDDVILNSLGGIIGINIYINMNKLFPNDINRFKAII
                     GTSLVLGVIGLGVISKNYHNLLTFKFRPDRKISKILIEENREIIKDINKDTVDIVGTF
                     ESFKKGIITIKAGSNNKVKRPENLIDSDGNIRIYLNENTKLVSYIITKESKMDIVKYE
                     EFDVKNLDLLRRYDTINVWIDKENQPKDKHGIMASKLLIGLYE"
     gene            30072..30857
                     /locus_tag="KR231_001926"
     CDS             30072..30857
                     /locus_tag="KR231_001926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433968.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0004303.1"
                     /translation="MEIIKYILYFFIYSFLGWTVESIGCSIASKRIINRGFLNGPICP
                     VYGFGAVIVISLLGRFNNVVIVFLLGMILTTILEYFTGFILETLFHAKWWDYSDKKFN
                     IKGRVCLKNAIYFGVMSVLIIRFIHPFIKYFVSIIPYRILISMAIITTLWTILDLIVT
                     IITLKKLDIKLNLLDDIITDLNDINVKLDKFDRGEIQALFKTINNDELEVREKINKIN
                     SKLDRIESNIILQKRVIKAFPHIKHKKQQEQLEHFKKIINEKR"
     gene            31149..32468
                     /locus_tag="KR231_001927"
     CDS             31149..32468
                     /locus_tag="KR231_001927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class III-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="HBH0004304.1"
                     /translation="MSEITSQMISTEEKKYVAKTQKIPYYPVAFKSGDGAMLYDYEGN
                     EYVDFLASAGSANVGHGNKEISQAVKEQMDDITQYTLAYFHSDPPVKLAEKLVEIAPG
                     DNDKKVLYSATGSACIDAAIKLARGYTGRTKIISMCESYHGSTYGAISISALSTNMRR
                     KMGPLLPEVYHFHYPDKNRTAKECLDEIEYAFAHYLPAEEVAAIFIEPIAGDAGIIVP
                     PVEWVQGLSKICKENGILLVSDEIQQGMGRTGKWFGIENFGVEADLIVLGKSVGGGLP
                     LGAVVGRTEIMQSLDAPAHLFTLAGNTTVCVAALKSIEIIEKENLLQKSIEMGDYIKA
                     GFEKLKEKYDIIGEIRGIGLSIGVDIVKGKGSNEKHPDATAKICYRCIQTGLIMIFLG
                     QSTLRVQPPLVITKEQVDKAMNIIDSAIDDYLNGRIGDEVYEVTQGW"
     gene            complement(32543..32971)
                     /locus_tag="KR231_001928"
     CDS             complement(32543..32971)
                     /locus_tag="KR231_001928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0004305.1"
                     /translation="MKDNNNTNKTIQFGEKKASLENNIQKNKNIKLDNTHKVIPYPKN
                     RKKDDKKKGNKKKNTNTSKVNKNNYGHSFFNNKYKYKRKPYVIALYTVILILLAILII
                     TKLTDSTNKGNYSRNTVSDTHKNDIRNIVFNESNNFLICG"
     gene            complement(33062..34438)
                     /gene="hydG"
                     /locus_tag="KR231_001929"
     CDS             complement(33062..34438)
                     /gene="hydG"
                     /locus_tag="KR231_001929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="[FeFe] hydrogenase H-cluster radical SAM
                     maturase HydG"
                     /protein_id="HBH0004306.1"
                     /translation="MFINHELINSLLEDAKNSTSDDIEKVLDKADRREKLSYKDIATL
                     LEVEDKKQLDRLFSIAGQIKNEIYGNRVVLFAPLYVSNYCVNECVYCGFSKCNKFKRK
                     KLTMEEIREEVKILEKMGHKRLALEAGEDPKNCDINYILDCLDAIYSTYNENGNIRRV
                     NVNIAATSVDEYKLLKEKGIGTYILFQETYHKPTFIKMHGQSIKNDYYYHLTAFDRAM
                     EAGVDDVGAGVLFGLSDPKFEVLGLMMHNEHLEEKFGVGFHTISFPRLKKAEGMSLED
                     FPHLVSDDMFKKIVAITRLAVPFTGIIMSTRETAEMRNELLKYGVSQISAGSLTGVGG
                     YKAYEDGDNTEQFEVGDHRSPVEVLKELITDGYIPSYCTACYRKGRTGDRFMSLAKSR
                     QIHNVCTPNALTTLNEFLIDYGDEELKIMGKKLIAEEIGKIEREDIRNIVSNNMTALE
                     RGERDLYL"
     gene            complement(34439..35524)
                     /gene="hydE"
                     /locus_tag="KR231_001930"
     CDS             complement(34439..35524)
                     /gene="hydE"
                     /locus_tag="KR231_001930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="[FeFe] hydrogenase H-cluster radical SAM
                     maturase HydE"
                     /protein_id="HBH0004307.1"
                     /translation="MTKNKIKYFIDKLYSINSLSFDELLYLIENIDNEEYNFEQNLRN
                     YLYKQASDMRNKHYGNRVYLRGLIELTNYCKNNCYYCGIQSSNKNIIRYRLSLDEILE
                     CCDIGYKIGYRTFVLQGGEDAYFTDDKICEIVSSIKNKYEDCAITLSLGEKSYDSYKK
                     YFLCGADRYLLRHETATDSHYKKLHPPNIELRTRKECLKNLKEIGYQVGAGFMVESPF
                     QNNEDLVRDLLYLKELNPHMVGIGPFIPHHDTIFKDYKHGDLEKTLLMLSITRLLLPK
                     VLLPATTALASINPSGRNAGLLAGCNVIMPNLSPQEFRKQYSLYDNKAFTGQEACEYH
                     QSLEENIKSLGLEVDYSRGDNIEWRRL"
     gene            complement(35560..36768)
                     /gene="hydF"
                     /locus_tag="KR231_001931"
     CDS             complement(35560..36768)
                     /gene="hydF"
                     /locus_tag="KR231_001931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="[FeFe] hydrogenase H-cluster maturation GTPase
                     HydF"
                     /protein_id="HBH0004308.1"
                     /translation="MSLNSTPQSVRVHIGLFGKRNAGKSSIINAITNQSAAIVSDIAG
                     TTTDPVFRPMEILPIGPCVLIDTAGLDDVGELGELRIGKSLDVLEKTDIALLVVDCQI
                     GISQEDLSLIEKFNDKNIPHILILNKIDTIKNQSEILNLTKNKVKCPVVSVSSTDKIG
                     IENLKNEIIKVLPKDSTEFKLVSDLIEPNDLIVLVVPIDKAAPKGRLILPQQQVIRDI
                     LDSGAISIVTKEDSLKETLSNLGKKPKLVITDSQVFPQVDKDTPKDIPLTSFSILFAR
                     QKGDLKELINGAYALENLKDGDKILMAEGCTHHRQTDDIGTVKIPNMIRKKTGKNITF
                     EFSSGVSFTEDINKYALVVHCGACMMNRAGMLSRIEKAKSFNVPIVNYGILIAYVKGI
                     LERSLELFNY"
     gene            complement(36783..37034)
                     /locus_tag="KR231_001932"
     CDS             complement(36783..37034)
                     /locus_tag="KR231_001932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003361768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-only hydrogenase system regulator"
                     /protein_id="HBH0004309.1"
                     /translation="MKKVAVISAILEEPKECQFKFNEVVSGFKGIIKGRMGIPCEEEG
                     VSIVCIAVVGEMDTINSLTGKLGNIPHVSVKTSISKKEV"
     gene            complement(37415..38455)
                     /locus_tag="KR231_001933"
     CDS             complement(37415..38455)
                     /locus_tag="KR231_001933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M42 family metallopeptidase"
                     /protein_id="HBH0004310.1"
                     /translation="MNLNLTNTINLMKKYLDIPSPAGYTENAVLEIKKDFENLGLDTI
                     LTKKGALIATLPGEDDSNQITISAHMDTLGAIVKEISSDGTLKYHKVGGGCWAAIEGE
                     NCTVITRKGKKIRGSVVFKYASTHIYGQTKAATERNEETMIIRLDEKVFTKQDVLDLG
                     ISVGDFVCLDHRFEATESGFIKSRYIDNKSAVAMVLEICRYFKENNLTPKHTTNFYIS
                     NYEEIGHGVSKCLPEKTKEFVAIDIAPTGPSQTSSEHGVTIVAKDNLSLYDFNLRNKL
                     VDVAEDNNLDYAVDVFTFYGSDASEAIRWGEDVQIACVGPGTNNSHHYERTHIEAIEN
                     TLKLLINYMLKE"
BASE COUNT        14791 a         4385 c         6242 g        13352 t
ORIGIN      
        1 gataaaataa gacaaatatg ttaaaaaaat gataatcacg gagaactttt accttcttca
       61 attaatatat tattattagt aataacttta aaattatatt actattatat aaaaattggc
      121 ttaaaagaag gtgaaaaaag taaatgaaaa tatgcataac agtaggtcat agtatactaa
      181 aaggtggtaa aagtacaggt gtaaatggta tagttgatga atacaattat aataaaaaat
      241 tagctcctat gttagctgag atgcttataa gtcaaggtaa tacagtagat gtaataattt
      301 gtccagaaag gcactttatg tcagaaagag aagaattttt ctatagagtt ccaaaagtaa
      361 acagtggtaa atacgattta ttagtagagc tacatttaaa taaagctgat ggaacacaat
      421 gtggtacaga agtgctttac tatggcactg aaggattaga atatgctaaa agagtatcta
      481 atagacttgg agaattattt gaaaatagag gagctaaaaa aagagaaaat ttatatatat
      541 tgagaaatac aaatccagtt gcaatacaga ttgaaagttt tttctgtgat aatgtgaatg
      601 attgtaacaa agcaaatgaa tcaggttatg attatatagc acgattgatt acagaaggta
      661 tattgaataa agatataaat atgtgagatt atggtgattt aggtattgat taataccttt
      721 taatattaga tataaataaa aatacaatgt attagtataa tttaaacttt caaaagatag
      781 attagtttga ttattgacaa gagatacctc cttgaaaata ttgatttatc agtatattta
      841 aggaggtatt taaatataaa aatttaatta atttgctact aaactatagg tttatagagt
      901 atatattttt atcttcagtc taataaataa tataaaaata gtagaacctt gtattataat
      961 aatataatgt agaaaaatat atagataaga taaatataat aaggtggtaa tatatgaaat
     1021 atacatttga aaaatttaag ttaaatgaaa agatacttaa gtcattgaag agtttaggat
     1081 ataatatacc ttctagagta caaagagaag ttattccaaa attattaaaa ggtcaaaact
     1141 tagtagttag gtcaaaaaca ggaagtggaa agacagcaag ttttgcaata cctttatgcg
     1201 agaatataaa tgtagattac aataatattc aagctcttat agtggttcca acaagagaat
     1261 tagccttgca agtaaaagat gagatatcag atatagggag actaaagaag gtgagatgta
     1321 gtgctatatt tggtaaacaa tctataaaag accaaatagc tgaattgaaa caaagggttc
     1381 atattgttgt agctactcca ggcagaatac ttgaccatat aaatagaggt tctattaagt
     1441 tggaaaatgt aaagtattta gtaatagatg aggcagataa aatgtttaat aaaggttttg
     1501 ttgaacaaat ggaaaaaata ttattaaatt tacctaagga gaaaatagta agtctttttt
     1561 cagctacaat agatgaagag ataaaatata tatgtgaaaa atatatgcta gattacagtg
     1621 ttataaatat agaagaaaat gagagcgata ctaatcaaaa aacaagacaa atagatgaca
     1681 aaataatcaa ggcaaatgga agagagaagt acatcctttt aaaagaatta atatacagcg
     1741 aaaatccaaa gagtgtgata atattttgta ataccaaaga gaaagtatct aaattatata
     1801 acaagatgag taaagaaggt tttttaataa gagagttaca tgcagattta tcacaagaaa
     1861 gaagaatttt tgtaattaag gattttaaaa accaaaaatt taatgtatta gttagtagtg
     1921 atgtagcgtc cagaggaata catattgatg atatttcttt agtaataaat tatgatgtgc
     1981 cacaagataa agaaaactat atacatagaa taggtagaac tgggagaaaa ggaaatagtg
     2041 gaaaggcaat tactatagta actgaaaagg atgaaaaata tatagagaat atagaaacgt
     2101 atataggata taaaataaat gaattaaaag atatagaaaa aagtagaatt acacatggca
     2161 aaattttgtt tgaagaatat tcaaaaggaa tcctaaaaaa agtatcaaag agaaaaaaag
     2221 ttgataaaaa ttcttacaat agtaaagata taaaactaaa tatagaaagt gaagttgtta
     2281 aattatattt aaatgctggt aagaagaaga aaataagagt tttagatata gttggtgcat
     2341 ttagtaatat aaaaggtata actaatgatg atataggtgt aattgaagtt caagatttat
     2401 gttcatatgt agatatatta aattataagg gagatttgat attaaaaaaa tataaggaga
     2461 tacctataaa gaaaaaaatg gttaaagtga aaagagatat acgataattt agtcaatatt
     2521 gatgaattgc tttgttatcg aaatgaagtt gcaaaaaaca caatagaagt tgttaaggat
     2581 ttgaaagctg aagatatgaa acgaaaggtc tctccaattg acttagaaag gattttggtg
     2641 actggaggag taataaagca tgaagattct atttggttgt tggacttttg ggggaataaa
     2701 gatattgctg gaattttgct tatgcctcct actcgtcatg ttatacttca tttgaatgat
     2761 tgttgtaaat ggaaggaata ttttcgtaca aaaaagaaat tttacagaag ttaaattata
     2821 ataaattaga caaacaatag ataaattagc aaggaatgtt gattttatct acattctaag
     2881 ttatactatt tttaagtggc taatggaata gtcattttaa atataagtaa taaatatata
     2941 cctataggga tattaaaggg gggaaatata tggcatattt taactataac gacaaacagt
     3001 gctactataa tgaaattggg gatggtacac cattactttt tttacatgga aatacagcct
     3061 cttccaagat gtttaatgat ataatcgatt tttataaaga tgaatataaa gtaatattaa
     3121 ttgattttgt aggtcatgga aaatctcaaa tggtcgataa attttctgct gacttatggt
     3181 ttgatgaggc tatgcaagtg atatgttttt tagaagcaat gaactataaa aaagtaaaca
     3241 taattggtag tagtggagga gctcttgttg cattaaatgt tgcacttgag agacctgatt
     3301 tagtgaataa ggtaattgca gatagttttg aaggagaagt tcctctagag tcatttgtac
     3361 aaaatgtgaa aatagagcgt gaagcatcta agcaagatga tggtgcaaaa gctttttata
     3421 tttataatca aggagaaaac tgggaaaaag ttgtagataa tgatacagaa gctatttttg
     3481 aacattataa aactatagga aaattttttc ataagcctct agaaactatg caaccagagg
     3541 tgcttttaac aggaagtaga gaagatgagt ttgtatctct aatatctagt gatttttttg
     3601 aaaatacttt ttcattactt cttgaaaaga ttaaaaatgg taaaatgtat ttgtttgata
     3661 aaggtggtca tcctgcaatt ttatcgaatg gattagattt ttcaaatgta gcaaagaaat
     3721 ttttagagga ataatttaac caaaatttat aataatgaaa actgtaaaat ggattgcaaa
     3781 acttacaaaa gtgagtgtac atatacttca ttattatgat gaaatagtat tgttaaaaca
     3841 aaatattcta atagtcaagt tattacattt gtatatgcaa tatgtataga aagagatatc
     3901 attagattgt aaagttggga ttaaataaca atattaaatt ttatttattc agatatttta
     3961 gcttaactat ataaatgtta gaacaaattt atatagttaa gctgtaggat taaataattt
     4021 agttaaataa gtttattatc tcctcatcag atagactttt taatacacct tcattagaaa
     4081 gttctccatt tataaattga tttataagct cttttttact ttcttgtaat tttattattt
     4141 tttcttctat agtcccttta gcaatcaatt ttataacttg tactgaattt ttttgaccaa
     4201 atctatgagc tctatcacta gcttgatttt ctactgatgg attccaccat gggtcaaagt
     4261 gaattaccat gtcagcagat gtaagattta aaccagttcc gcctgctttt aaagatatta
     4321 aaaaaacttt tttatccata ctattattga actcatctac aagttcaagt ctttctttgg
     4381 cattagtttt accatctata taatggtatt taattttata cttatcaagt tccttactta
     4441 tgttcttaag cacagaagta aattgtgaaa acaataatat tttgtggttt tcgtttatac
     4501 tatccctaag tatttctaaa catgtttcaa tttttgaact ttttttattg taatctttta
     4561 ctactatact tgggtctaaa caaagttgtc ttagtttagt taaataagaa aatataacta
     4621 ttttatcttt ctttagattt ttatctttca ttttatcttg tatatctttt gaatatacac
     4681 tatatatctt tttctgctct ttattcaatt caacaaaaaa gtttttttca atcttatctg
     4741 gaagttcttt cataacttgt tttttacttc ttctaagaat aaaaggtttt atcaattttt
     4801 tcaggttttt aacattatct tctttattta taaacaattc ctgaaacttt gctttactat
     4861 atagatagcc aggcattata aaatcaaata tagaccataa ttctagtaga ttattttcca
     4921 taggtgtacc agtgagtgca aatttatttt ctgcatttat actttttaca gactcagtta
     4981 ctaaagctac tggatttttt atattttgag cttcatctaa tatacaataa tcaaacttta
     5041 tttcactata tttttctaaa tcatttctaa gagtaccata tgttgtaagt attacatcaa
     5101 aattttctaa ttccataaaa catttttctc tatctctttt atttccatgt atcaataaaa
     5161 cttttatatc tggagcaaac ttttcaaatt catttttcca attataaatg agtgatgtcg
     5221 gtgtaacaat aagacttttt ttattagata atgataataa aaatgcaata gtctgtattg
     5281 ttttaccaag acccatttca tcagctaata taccaccaaa tttataataa tctaaaactt
     5341 taaaccaatt gaggccattt atttgatagt cacgaaggtt tgcatttaaa tttgcgggaa
     5401 tttctaaatt tatgctatca aaatttctaa atttttcaca tatactgtct agttcttttt
     5461 taccatctat aaactttaaa tttttactac gtattacatc atttatatat agagctttat
     5521 ttttatgaat tttattattt tttgatttat ccattatatc tagattttca actaattcaa
     5581 aaaaatcttt tgtttctctt tctgataaat ctataaagtt tccatcttta agtttataaa
     5641 aagtacgttt ttcttgaaaa gctttcaaaa tatccttgta ctctcttgga tttatatcag
     5701 atatattaaa attaaattct aggtaattct ggttagtctg attgattgaa gcttgaattg
     5761 atgaagcgtt atatattttt ttcaatttaa acttctcaga ataatatata tctccaaatt
     5821 cctttagaga ttctaattgt aaatctaaaa atgtaaatag gtcatggtca gttcctttaa
     5881 acacataatg attattttcc tttgtaaatt gtgaagaagt aagtttattt tcaatagtag
     5941 cttccttttg tatgttgggg agcacaaatt ttttatcttc atcatcatat atatacttta
     6001 catcacaaca tatgttgcca tcaatcatat caaagtagaa ctcagattta aaatcttttg
     6061 ttatattatt ttttatgtta tcatctaaat gaacttcttg agatatagat tttaatctag
     6121 gaactagcaa tcctaaaaca tccttagaat cctctttatc aaattttaac tctttagtct
     6181 ttgataatat ttgatatatt tttgaataat catgagcttt tttatgtgat aataaataga
     6241 tattgccatc atataaaagt acatcatttt ttttagtaag tggaacaggt agtgaatctt
     6301 tagaatataa gactatttta tcttctatat ttttaaaatc aaaccttaca ggtagagtat
     6361 catttaatat ctttggatga tattcctctt tagaaaaaat aagggtaaaa tccttgtact
     6421 taatagcatt taaaaattgt tttaaagagc ttgcatttat ctccataaat ttttttgaat
     6481 gtgatgaaga aaagttgtat gaaagatttg tcccatattc ttctataata tctactaact
     6541 tctcatcttc atcagcaaaa taatgagtgt tggggttgta agtaaatttc ttcccaaaat
     6601 ctaattcata tccattaagt tttgaatatg caaattcagt aatgtttttt aaaatgtaca
     6661 ttttatcaat tcctatttta aattcagcaa ttgctttatt tgaatccaca tttatcaata
     6721 catctaaatt aaccctttct cttttagtat tgtctaacaa agaaagtaat tgcttgctta
     6781 aatctaagct ggttttagaa tttgtattag aaagcttatc cttatctgca cctaatatat
     6841 ctattagaat aggaggaaca tcttttttat tttttatttg ttttaagctt tttatcacaa
     6901 tagcaactat atgcttacat ataaaaatac ttttgccctt tgattgacag tcagcgcaac
     6961 tacaatcatt ttcaattatc ttaaagtgct ttatatctat agttattgaa ttaaaataaa
     7021 agctataatt atcttcagaa ttgactccac cacgaaatgt caacaggtta ttttgtaggt
     7081 catcaatatc tatgtctata taatcaacta attgattagt ataatatttt acacctcttg
     7141 accatcttga tggttctgta tttcttctta ttagtttata tatcatatct attttcatat
     7201 tattcacctt acctcactgt atatattata atctaaatgc attcaattta cactctaaat
     7261 ttaagactaa aattaaggca gatatgaata gcttttatct atcacaatat atgtgtaaat
     7321 aacaatttac tattagattt ttattgaatt atcttataaa ctatgaatga aaaataatta
     7381 tataaataga ttattaataa atataaaatc ttattattaa aaatattctt agaaattaca
     7441 ctatataaaa tataaagtat gatatttgaa taaaaagaat gtataataag tataataatt
     7501 tgtatttatt attgggaaag gaaaatgtta atatggatag ttatagacaa cttaaagcta
     7561 aaataccctg taaggaaaca ggtatagaaa taaagaggac tttatgtgat atttgttctc
     7621 caggagtaca ttgtggaatt gatgcatatg ttaaagatgg taaagtaata aaaatagaag
     7681 gtacaaaaga acatccaatg aataaagggt tgttatgtac caaaggtctt tgcaatagag
     7741 aatatatcta tagagaagat agaataaaaa cacctctaaa aagaattgga aaaagaggtg
     7801 aaggaaaatt taaaccaata tcatgggatg aagcttatag agaaatagca gaaaaattaa
     7861 atagagtaaa atctgagtat ggagcaaagc atgtagcttt ttttacgggt tatggaaagt
     7921 ggtatagacc ttttttacaa aggtttgcat cttcatttgg ttcacctaat tatggtacag
     7981 aatctagttc atgttcaaca tcagcacaga tggctggaaa tgttgctact ggaagaaact
     8041 ttacaatgca agatatggag aatgcaaaaa cttatttagg gtggggattt aatccatact
     8101 actctaaatt tttaaatagt gtgaatctaa taaaattaaa agaaaaaggt ctaaaattta
     8161 taattgtaga ccctagaata acaccgacaa ctcaaaaact agcagattta catttaagaa
     8221 ttaaacctgg aactgatgga gctttagctc ttggaatggc gaatctattt atacaaaagg
     8281 atttaataga tagagaatac atagaaaagc atgtacatgg atttaatgaa tataaagaat
     8341 atgtaaaatt atttgattta gatactgtaa gtagaattac aggagtttct aaagataata
     8401 tagtaaaagc tgtcgagatg ttgtcacaag gtccattttg tataaatgaa agtgcagctc
     8461 caatagttca ccatcaaaat ggatttcaaa attatagagc aatgatgtct ttatccgcta
     8521 taacaggtaa ttatgataga ataggtggaa acataccaaa acaagattac tttgctggta
     8581 agataggtgg attccaaaca ctagaaaaag agtttgtaaa agaagttcta cctaaaaata
     8641 taaatgaaag aattggtgga gaaagatttc ctctatggaa tgaaatggtg actcaatttc
     8701 aagctatgga tttacctagg caaatagaag aaaagacacc atatgaaata agagctttgt
     8761 tttgtcatgg gataaatgct agaatgttta ctaattcagg gagacttttt aaagcgttga
     8821 atagtgtaga tttttttgtg aatatagatt tatttatgac agatacatca aaatatgcag
     8881 atatactttt acctgcatgt acatcatttg agagagaaga atgtaagagt tatccaggag
     8941 ggtatattac atataccaaa aaagttattg ataaattata cgattcaaaa tcagatgtag
     9001 aaatactttc agatttagca aatgctatga atatagatga tgatttatta aaagcaggtt
     9061 atgaagcaag tataagacat atgtttaaaa atacatgtgt agatgtagat aaacttaaag
     9121 aaagtgattt accattaaaa tgtaaagatt ttaagccata tatagtaggt tcatatacaa
     9181 gagaagggta tgatactagc acttctaggt ttgaattaaa atctacaatt attgaaaaat
     9241 ataaagattt tgggctggat gcactaccaa catatagagg atttaatgat aatatagatg
     9301 atgaatatac tcatttattg acatcaggag caagaatttc aaatgcacta cattcaagac
     9361 ttcatgacat caaactttca agaatattaa aaaatgaagc tagttgtgat atttctagct
     9421 tagatgcaaa agaattgggt gttatcagtg gagattatat aaaaataact actaagatag
     9481 gaagtttgga tgtaaaagtc aatgttactg atagagtctt atataagaat atacatatgt
     9541 atcatggata tagagaagct gatataaata gtattatttg tgataatttt gacccttata
     9601 gtggattccc tgcgtataga agttgtaagt gtaagattga aaaaatgaat agataaatgg
     9661 agagatataa tgaaaagttt atttaaattt aataaagaat tatgtacagc atgtggagca
     9721 tgtttgcttg catgtataga ccaaaatgat aataatatag acaatggtga actttttaga
     9781 catgtattta caatagagga aggtgaaaat atagaatatt tttcattagc atgtatacat
     9841 tgtaatgagc caaaatgttt aggtgtatgt cctaaaaatt gttttaaaaa agaagaagga
     9901 ttcattgtat tagacaatca aaactgtata gggtgtaaac tttgtgaaaa agcttgtgaa
     9961 tatggagcct taatttatgg aaatgatggt aaggcaaata agtgtaatgg ttgtattgag
    10021 agatataagt gtggtatgga ttcaccttgt gtaatggtat gtcctacagg agcattaaaa
    10081 tttaataaat aaattaaata tagagaatga cttatactta ggtataagat atttttacaa
    10141 aaagctgtat tgagtttgtt ataatgaaaa ctcaatatag cttttttatg gatatagttg
    10201 gatactataa tgtgattctt agtaatagtt ttttgctatt ggacaaagac tgtaaaacat
    10261 attaaactta tgttgttcaa agtcgaagta taatataata actagaaaat tggtttatag
    10321 tgctataaaa gcaaatttag taaggtataa aatcagaggc aatcctttac tataatatca
    10381 atatttggga gttctgttat tgcagagcta ttaaacaatt ataatggtac aagtgattca
    10441 acctttgaaa atgtattata taaaaaatta aaataagatt aaaaaggaga gaataaatta
    10501 tgaaaaaact taaattaatt attatgtttg ccttggtatc agcactgtta gttacaggat
    10561 gttcatcagg aaataataaa aataaagaag aacaaaaagt tataagagtt gcaacatcag
    10621 gaacatatta cccttttgct tttaaagata aagataaact taaagggttt gaagtagatt
    10681 tttgggatga atttgctaaa cgaactaatt gtaaagttga atgggtatta actgatttta
    10741 gtggattatt tggattatta gaagctgata aagcagatgt tgtatctgct caacttactg
    10801 caacacctga aagagagaaa aaatatgctt tttcagatgc ttataattat agtggaacaa
    10861 acattattgt tagagaagat gatactagta taaaatcaat agatgattta gttggcaaga
    10921 aagtaggtgt gggtactgga gcagtagcaa atgaaatatt aaaagaaaaa tacccaaatg
    10981 atgaaataaa aatagtaaat tattcaagtg cgactcttaa agggaattat caagacctag
    11041 aaatgggaag attagatgca gtagttgcgc aggatgttga ggctttaata gctataaaag
    11101 aacaaaaatt aaatcttaaa atgatagaac ctccaattca atttggtgcc tgttcttttg
    11161 cgcttcaaaa aaatgaaaaa ggtgaaaaat ggacaaaaga aattaacgaa gtaattgaag
    11221 agatgtataa agatgggact ttgactaaaa tatctgaaaa ctggctagga aaagacatta
    11281 ctaaggagcc tattaatgag taattttaat tttgaatttt gtctaagtat atttccattt
    11341 ttgattaaag cattgggaat aacaatacta atatctattg ttgcattttt tttatcaata
    11401 ttattaggtg taatacttgc ctttttcaca cagacaaaat caaaagtttt acaatacata
    11461 acaagagtgt atgtttcatt ctttagagga acaccacttt taattcaaat atttttcttt
    11521 tattttggat ttccaatgat attttctttt atgaaagatt gttcacctta tttagcaata
    11581 gtaatttgtt taggtgtaaa ttcatctgca tatatggctg aaattatacg agcatctatt
    11641 gagagtgttg ataaaggaca acaggaagca tgttatgctt ttgggttaag taaatatcag
    11701 tcaatggtta aaataattct acctcaagca gctacatctg cagtacctcc tattgtaagc
    11761 tgtacactgg acataattaa aggttcttct ttaggtttaa ctataggaat acaagattta
    11821 atgggagtag ctcaagtaga ggctgcttca agttttaaat attttgagat atatatgata
    11881 acgatattaa tttactgggc agtatctata atattgagta atatacaaag caaagttgaa
    11941 aaaagaataa gaagagcata ttagatttca atatttaaaa atgggatgat atagatatat
    12001 tattacttgt aaataaattt ttaattttag aaaaataaac ttagtaatct aaattattga
    12061 gaaaatatag tatcaaaatg gactgtataa tcaagttaaa aaatagtttt tctattgaaa
    12121 aaataaataa aattctattg taatttaata tgcgataaag ttttataaaa aacaacatta
    12181 agctaggggg acttatttta tggcttttaa tatgaaatat tttttagaat tatttccaac
    12241 aataatgaaa tcgttcaatg taactgtgat tttggcaata agttcattag tattttcatt
    12301 aattataggt acaatagtag cgttatcatc ttattacaaa gtgaaagtat tgaatcaaat
    12361 atgtaaagta tatgtatcta tttttagagg tacacctctt atgccacagt tattcttttt
    12421 atattttgga ctagcatata tgagtgattt tgttaaaaat atggacccag tatttgcaac
    12481 atctatagta cttagtttaa atatgggagc ttatatgtct gaaacgataa gggcatctat
    12541 actttcaatt gatacaggtc agatagaagc agcatatgca atgggattaa caaatttaca
    12601 aacaatgaaa aggatagtga taccacaggc cgtaagagtt gcactgccat cattattcaa
    12661 taattttata gatttaatta aagggtcttc tgtagctttt gttgttggag taaatgatat
    12721 aatgggtgct gccaaatcac aaggagcgtt gagttttaag ttttttgaag tgtatggagc
    12781 agttatggta atttactggt gtataataac tcctttaggt tgggggcaaa aaaaattaga
    12841 aaagaaaata agcaattatt aagttattaa gaaaatacat aaaagtattt ttatataaaa
    12901 aatggtgtga ggagaagaga tatgataaaa agaaatatta taaaatgttt agtggcagtt
    12961 ttatcgttaa cgtttgtaat tactggttgt tcaaaaaaag aggaagtaaa gaatgaaaaa
    13021 gttataactg tagcttcatc taattcagct gacccatatt cttatgttga taatggtgag
    13081 cataagggtt ttgaagttga catgtggaaa gagattggta aaagaagtgg atataagata
    13141 aaaatggaac caacaggttt tagttctata tttggtatgt tagattctgg taaagttgat
    13201 gtggcagcca acttctttgg aatgtctaaa gaaagattag aaaaatacga tgcttctata
    13261 ccttatggtt ctgattctgt gtgtatagct gtaaaagatg gaaataacga aattaataag
    13321 cttgaagatt taaagggaaa agttgtagca gtttcagaag gttctcaagg tcaacaggtt
    13381 gcaactagtg ttaataaaga taatttgttt caagaaaagg tttacggtga tggaactagt
    13441 ggtcttcaag atttagattt gggaagagtt agtgcatgga ttgatgcaga gcttactatt
    13501 gtgggagacg ctaaaaaagc taatatgaaa gtaagagtat tagataaaaa attatcagct
    13561 actaatatag catacttctt taagaaaaac gatgataaat ctaaaacgat aaaagaagat
    13621 gtaaacaaag caatagaaga aatgcttgca gatggaacag tgaaaaaaat atctgaaaaa
    13681 tggtttggaa tggatgtaag tgctgatata caaaaataaa tactttaaaa ttaaaatgta
    13741 aaactgtgat aactatagat aagtatacta aatttatcta tagttatctg tgtattacaa
    13801 tgtatttaga ttagtcttta taaatcaaaa tgagttatgg aggtattgca aatgattgaa
    13861 actaaaataa aatccattgc actaaaaaat agagaaaaaa ttataaaaat aagacgacag
    13921 atacacagta atccagagtt agcatttaaa gaatataaaa catctaaact tataaaagaa
    13981 gagctaaata aacttaatat agaatacata aatattgctg gtacaggagt attagctact
    14041 ataaaaggaa aaaataatgg tggaaaaact atattactca gagcggatat ggatgctctt
    14101 ccaatcaaag aggaaaatga tttagaattt aaatcaataa atgataatat gcatgcttgt
    14161 gggcatgatg cacatgtttc atggttgtta ggaacagcaa tgattttaaa tgacataaaa
    14221 gaagaattga atggaaatgt aaaattacta tttcaacctg gcgaagaaaa aggtggttct
    14281 gatattgtaa ttaaagaaaa tgtacttgaa ggtgtggatg cattagcgac tggtcattgt
    14341 tggccaacta ttgagtcagg aaaaattgga atcgctagaa attgtgctat ggcagcgact
    14401 aatacttttg aaataacaat aattggcaag ggtgggcatg gagcagagcc tcataattgt
    14461 atagacccaa ttgcagttgg aaatgcagta tattcatcca ttcaacagat agtttcaaga
    14521 aaaattgacc cagttgtacc tgtagtagtg tctgtttgtt cttttaattc tggtgtttct
    14581 aaaaatataa taccagatgt atgtacactt caagggacta ttagagcgat aagcaaggaa
    14641 caagtaattg aagtaagtaa aattctagaa tatatagtaa aaaatgtatg taaagcacat
    14701 ggagcagatt gcaaatttga aaagagtaca ggaggagatg ctgttataaa tgacaaaaac
    14761 atgatagaga taggaagaga aagtgcttgc aaaatacttg gagctgaaaa tgttgaaata
    14821 attgattttc ctgcaatgac aggtgaggat tttgctattt atatgaaaga aaaacctggt
    14881 ttatttatgt atataggtgt aggagataaa gaaaaaaata taaattacag attgcatagt
    14941 aacaagttta atatagatga aaaatgtctt agtatagcac cttcattatt ttcacaactt
    15001 acagtagatt atttatgtca actatagagt acattcataa aaatatattt agcctatttt
    15061 taaatttaat gctagtatat taattttgat gtagaacata ttatttatta tatttattta
    15121 aaaaggtgga taacaatgat aaaagtagaa aatttacata aaagttttaa agggacagaa
    15181 gttcttaaag gtataaattt agagataagt caaagtgaag tagtagctat acttggatca
    15241 tctggaacag gtaaatctac gttacttaga tgtttaaatt atttagttga gcctacaaaa
    15301 ggaaagataa tgattggtga tgtaaaagta gatgtagaaa aagcaacaaa aaaagatata
    15361 accaatttaa gaaaacatac atctatggtg tttcaaaatt ataacttatt taaaaataaa
    15421 acagcattag aaaatgtaat ggaggcattg atagtagttc ataaaaagag taagaaagaa
    15481 gctagagaaa tatctttaaa attaatagat aaagtaggta tgttggatag gaaagatttt
    15541 tatccatcaa agttgtctgg gggacagcaa caaaggatag gtatagcgag agcgatggca
    15601 gtaaatccaa atgtaatatt atttgatgag cctacatctg cacttgaccc agaacttgtt
    15661 ggagaagttt taagcgttat aaaatctctt gcaaaagaag gtataacgat gcttattgta
    15721 actcacgaaa taaattttgc aaaagaagtt gctgataaaa ttatatttat ggataatggt
    15781 gtaatagctg aagaaggaac tcctgatgaa atatttaata atcctaaaaa tgaaagaaca
    15841 gcaaaatttt taaatatcat taggaaagaa gaagtattta gttaaaagtg tataaattaa
    15901 gcattagaag atatgtaaga tacccccatt aaatttataa gttagataat aaatttaatg
    15961 ggagtatatt tttattatta gatttattat ttaatttaaa attagaaatg taactatttg
    16021 aaaattcttt ttaaaagtat atcaaaatat caaatacata aaaaaataat atttgacaaa
    16081 gtatcatatg tgtttacaaa atcaacttta tggagttata tagtatagga attacaatga
    16141 atatactaaa attttatatt aaagtacaaa gtattaaatt tgaaaataat taagtaatat
    16201 tatatatatt tttttatatt gtttgtttta ttaaaattaa tctagaaaaa aagttttaaa
    16261 agcagaattt tattaatatt tatatataga tatgaactat taataaaacg ttaaaaatac
    16321 aaaaaaacta tagaaattga catatattcc agtatttgct aaagtagctg ttggggaaaa
    16381 ttacaaaaat tattaatgcg cattagataa tttactttaa tttttttagc atttggggta
    16441 atttataata taaagcatta gaaaggaaaa tataaatgag ggacttttta aaaaattata
    16501 agtcatcaat tatactttta gcatgtacta tagtaggggc gatagtagga ttagtacttg
    16561 gtccaaaagc ttcaatacta aaaccatttg gagatttatt cataaatgct ctattaatga
    16621 tagtagtacc attagttttt cttagtgttt cttcaggtgt tgctagtata aaaaatatgg
    16681 aacgatttgg aaaaataatg aagggtacag ctatagtatt tatgggaaca acacttgtaa
    16741 ttgcattttt aggtattaca tctgcattat tatttaatcc gtctaaagga ttagatgtat
    16801 caagtgtaaa aaatttaatg gtgactcaag atgcagaaac tttagaatca aaaggaacgt
    16861 tattagacca agtagtatca agtattacag ttaaaaattt tggagattta ttttccagta
    16921 gtaatttact acaattagtt atatttgcag ttttaattgg aacagcaata gctatgatgg
    16981 gagatagggg aaatacaata agaaagcttt tatcagaagg aacggaagca atattaaaag
    17041 tagtaagtat attcatgctt tatgctccta tagggctagg ctgttataca gctacaataa
    17101 ttggggaact tggaagtaaa ataattcaag gatatgtaag ggtgtttgta atttattcac
    17161 taacagcagc catgtatttc ttattatttt acagtctgta tgctttttta tctgcaggaa
    17221 aacaagggtt tagacaattc tggagaaatg ctataaaacc aatagcaacg gcactagcta
    17281 cttcttcaag ttcagcatgt ataccatcaa atttagaagc tagtaaaaat ataggagttc
    17341 ctgatgatat atcagaaaca gttatacctc ttggaataaa tatacataaa gatgggtcag
    17401 ttttagcagt aataataaaa gtggcatttt tatcaggtat tttaggtagt ggaatggcaa
    17461 atccagcaac gataggtcaa ttatttataa ctgtatttgt tgttggagta tttatggctc
    17521 ctgtagcagg tggctgactt attggtgaga tgctcgtggt tagcatcttc ggttttccag
    17581 tggaggcaat tccactgtta acagttataa ctactataac tgatattcct aatactatat
    17641 taaatacaac tggaaataca gtatcatcaa tgttagtttc aagattagta gaaggaaaag
    17701 attggcttat agataaaaca gcaattacta caaagaaaat aagctaattg tacacttaat
    17761 taataaagtt aataggtatc ttaattttaa taaattagat acctattaac tttttaagta
    17821 aaaatataaa tttaagattc aaatatgata tttataattt gaatcaacta atatagtata
    17881 tattgaaata aatatgttta aatatctatt ttatttttta aaataaaaga tttcaaattt
    17941 atttttgtta aaagataaca agccttcatc tcgcatcttg ccaagctctc ttgacataga
    18001 acttctgtca acacataaaa aatcagccat ttcatttctt gaaaagggaa ttgtaaactg
    18061 gtggctacct gtttgttcta tctgttttga aaaatacata agcaatttct cgcgagttgt
    18121 tttacgagaa agtaattcta ttttattgtg aagtaaaatg tttttttcag ctattaattg
    18181 tagcatattt tcaacaagcc tattatgaaa tacacatgca gatgaacaaa taccagttac
    18241 acttttaaac tttatgaata aaacttcgca agaagatgtt gtggttactg taacattact
    18301 tttatgtagt ctagtacatg cgaatacctc tccaaataaa tctccaggca agagttcagc
    18361 tacaatattc ctattccctt cgatatcttc ctttattata tgagcacttc ctttaagcat
    18421 aattccaata gaagtaactt cacttccaac agagaatatt atactatctt ttgtgtaagt
    18481 cttatctaca acacctaaac attccaacat ttcttcaagt tcatcacttt taattccttc
    18541 aaatagagga atttttttaa gtaggtctat atgcttttct aaaaattttt tcaaataatc
    18601 acttccttgt tgcatatgca accgataatt tgttttcatt gtactatact aagtttataa
    18661 aagcaagggg atataaaaat cctactacaa gaaatttgaa ataaagaaat ataggtatta
    18721 aaaatatata tataagaaat caatacttta aattaaaaaa attttatgag gtgatataaa
    18781 tgatgagaaa aataattaaa attgatgagg aaaagtgtaa tggttgtgga ctatgtgttg
    18841 aagcttgtca tgaagaagct ataggaatgg taaatggaaa agcaaaactt ttaagagatg
    18901 actattgtga tgggctggga gattgtctgc caacttgtcc aacaaatgcg atttcatttg
    18961 agtatagaga agcagcagaa tatgatgaag ctgcagtaaa agcaaatatg gaagcaaaga
    19021 aagcacaaaa gaaaacttta gcatgtggat gtccaggttc tcagtctaag tcaataaata
    19081 gagaggtttc aaatagtatg tctataagca atgatatagt agagataaaa ggttctcaac
    19141 ttaatcaatg gccagtacaa ataaaattag taccaactaa tgcatcatat ttaaagaatg
    19201 caagtctttt aatagcagca gactgtacag cgtatgcata tggaaatttt cataataaat
    19261 ttatgaaaaa taaggttaca ttaatcggat gccctaaact tgatgaagtt gactatgctg
    19321 aaaaacttac agagatttta aaagaaaatg atattaaaaa tatagtagta acacgtatgg
    19381 aagttccttg ctgtggtggt atagtaaatg ctgttaagac agctctacaa aatagtggaa
    19441 aaatgatacc atggcaaata gttactatat ctgtagatgg aaaaattgta gatggagaaa
    19501 tttaattaag tgaattatag aaaaatataa taaattttaa taaataaaaa gggaggaata
    19561 aaaaatggaa aaaatgtttt gttttcaatg tgaacaaaca gcaggaggta aaggttgtac
    19621 tataaatggt gtctgtggta aaaagggggg tacagctaac ttacaagacg aacttacagg
    19681 agtgttgatt ggtctttcaa gagcaactat tggaaataag aatagaccaa caagtgaaac
    19741 agataaaatt atgatagagg ggctattcac tactataacg aatgtaagtt ttgatgatga
    19801 agctataaaa agacaaattg aaaaaactga ggtagaaaaa agtaagcttg tacctagatg
    19861 ttcagattgt tcaacaactt gtaatagaaa tgataactat gatatgaagg atttatggaa
    19921 tgataatgag gacatacgtt cattaaaatc attaatctta tttggattaa gaggtatggc
    19981 tgcctatgca tatcatgcaa tggtacttgg ttatacagac aaagacgtaa atgaattttt
    20041 ctatgaagga ttaatagcag ttggaggaga cttgtctatt gacgaacttt taggtctagt
    20101 tatgaaaact ggagaaataa acttaaaatg tatggaattg cttgatagag caaatactga
    20161 aacttatgga acaccagaac cgactcaggt atctatgaaa atcgagaaag ggccatttat
    20221 tgtagttaca ggacatgacc tttatgattt acacaaatta ttagaacaaa cgaaagataa
    20281 gggtataaat atatatactc atggtgagtt attaccagca catgcatatc caaaactaaa
    20341 agaatataaa catctaaaag gtaattttgg tacagcatgg caaaaccagc aaaaagaatt
    20401 tgataatatt cctgctccaa tattatttac aacaaactgt ttaatgcctg ttaaagatag
    20461 ttatagagat agagtattta ctacagaagt agttgcttat ccaggtatgg ttcatattga
    20521 tgaagataaa gatttttcta gtgtaataga aaaagctctt gaacttggag gatatagaga
    20581 agatgttcat atgactggta ttaatggagg agatacatta actactggtt ttgcaagagg
    20641 tacagtttca tctgtacaag ataaagtagt agatgctgta aagagtggag ctataagaca
    20701 ctttttattg gttggaggtt gtgatggtgc aaaacctgga agaaattatt acactgaatt
    20761 tgtaaaacaa gctcctaaag acactgttat attgacactt gcatgtggaa aatatagatt
    20821 taatgattta gaccttgggg atatatgtgg cttacctcgt ttaatggata tgggacaatg
    20881 taatgatgct tatagtgcaa ttaaagtggc agtttcattg gcaaatgctt ttgaatgtgg
    20941 agtaaatgat ttgcctctta gcatggtact gtcatggtat gagcagaaag ctgtttgtat
    21001 acttcttaca ctacttcatt taggtatcaa aaatatctat atagggcctt ctttgccagc
    21061 attcttatct aagaatgtat tagatatatt ggttgataaa tttgcattga cacctatatc
    21121 tactcctgaa gaagatatga agaagatttt aggataaata aacatatcta tacttaaaga
    21181 tatttatagt taaaatattt ttaagtatgc cacaattaag ataaggggtt aaacttaaaa
    21241 tttgattaaa aaatcaattt tgagatgacc ctttatttat tttttgtaat aattgaaaaa
    21301 taaacctgct ttcagtatat tctttttaag aatctttgta ttaaatttat aatacttaga
    21361 tatataatat cttatatatt ttattttaag tattaaaggt ttgaatgtaa cttaaatatt
    21421 aaaagaggaa cattgtaata tgtaacttgc ataaaatata tatactatag tgaaattatt
    21481 ttgattaaaa tttaaaatat aaggtgtttt atgtgggggt atatgtatat gaaaaattct
    21541 aattttaata tattggcatt tgatggtggt ggattaaaag gggcattgag tatatccata
    21601 cttgagagga tagtaaaaga gtatccaaat ctattaaaca atataaatat gtttggaggt
    21661 acatctacag ggagtctaat tgcactaggg cttgcgtatg gtgtaagccc taaagagata
    21721 aaagaacttt actcaattga aaattcaaag tatattttta ataaaagtta tgcagaaata
    21781 ctcagaccaa agtatgaaaa caaaaactta aaagaagttt tattaagtat atttccagag
    21841 gaactagaat taaaagattt aaataaatta gtaatgatac caagttttta tataggaaat
    21901 gaggaaaatg catggaaacc agtgttttat aacaatatgc caaattcttt tacaaagact
    21961 agcaaagttg tagatgtagc aatggcaagt agtgctgctc cggtattttt tccaacatat
    22021 aatcgtcatg ttgatggagg aataatagca actgacccga gtttagcgtg tataattcat
    22081 gccattgaca gtggatttaa acttaagaat acaagacttt tttcaatagg gactggatat
    22141 gtatataaca gtataaaggc agatactact gaatggggag ctattgactg gataattaat
    22201 aaagaacccg atttaccaat tatatctatt accttagaag gaaattctca aatgagtcag
    22261 ttattttctc aaaaacttct tggagataat tactatagat taaatcctaa gatggaaaaa
    22321 gatgtagcta tggatgattg tgatgcatta gaatatctaa tgtctttagg agaaaattgt
    22381 gatataaaag atgcttttgg atggataaag aaaaagagct tttatagaaa ttagattcaa
    22441 tttgcaattg tatttttaca catgatttca ttgagtaggt aaaaataata aaatgcagat
    22501 tattaagtta cttcttaggg aataaataaa gtataattta tttaaggagt gatgaaaatg
    22561 ataaaacttg ctacttttgc aggtggatgt ttttggtgta tggtaaaacc ttttgataag
    22621 tatgatggag ttattaaagt agtttctgga tatacaggtg gtcatgttga aaaccctaca
    22681 tatcaagagg tatgctcagg aactactggt catttagaag caattcaaat aacatatgat
    22741 gatgatataa taagttatga tgaacttcta aatatcttct ggaaacagat taatcctaca
    22801 gatgatggtg gacaatttgg tgatagggga actcaatata agactgctat attttatcat
    22861 gatgaagaac aaaaaaatat agctttagag tcaagagaac atctggaaaa tagtaaaata
    22921 tttgatagta aaatagtgac tgatataatt ccagcaacta aattctacga agcagaagaa
    22981 aatcatcagg attattataa gaaaagacca ttaaactaca atatgtatta taaagggtct
    23041 ggaagatata attttgtaaa aagccattgg gatggaaaca atataaatag ggaagagtta
    23101 aaaaagactt taactcatat acaatttgaa gtcactcaaa atgatatgac agaagtacct
    23161 tttgaaaatg aatattatga caataacaaa gagggaattt atgttgatat tgtaagtgga
    23221 gaagtgttat tttcttcaaa agataaattt gattctggat gtgggtggcc aagtttttca
    23281 aagccagtta tagataaatc tatcattgag agaagtgatt tctcacaagg tatgtacaga
    23341 gttgaagtaa gaagtgctaa aggaaattct catttaggtc atgtatttga tgatggtcca
    23401 aaagaacttg gaggtttaag atattgtata aattctgctt ctcttaaatt tataccaaga
    23461 gaaaatatgg aagctttagg atatggagaa tatttaaaac tttttgagta attaggaata
    23521 tttattataa acttatctaa aaggtgaaaa tataaaaaaa tattttcacc ttttgttttt
    23581 ttgtcaataa tatgataaat tattaattgt aatcttattt ataccaatag attaagaatt
    23641 taattttgaa agagagaaaa caaatgaatt taaaagactt taatggaaag agattaaaat
    23701 cagctagaat ttttagagca aagacgatag aacagttgtc taaagaaact aaaataaata
    23761 aaaaagattt aaaagctttt gaggaaaata agtatgtacc aaatatagaa aatacattaa
    23821 aattatctaa tatattaaat tttccaaaag agtattttta taaaaatgaa aatataaata
    23881 tcgttgtaga ggatagccac tttaaccctc aatctaaact acctagagta gaagagattt
    23941 cttatagaga aaaaataatt ataatacata aaatatattc atttatggag aattatatta
    24001 agtttccaaa agaaaacttg ccaaatagaa aagtaatgtc agatattaat ataaatgata
    24061 tagaatctct tgcatataag actagagagt tttgggattt aaatagtact ccaatagtaa
    24121 atatggtaag tttgttagag tctaaaggga ttataatatc aggtatgaat gtagatagaa
    24181 aaggggcaac tatctttact caaaaacaga gaattagtaa agaatctaaa tatctaatat
    24241 ctctgggtaa tgacaaaaag tcagcatcaa ttagaaatta tactttggca tgtgagcttg
    24301 gatatataat atcaagtgaa ttaagaatac caagtaagca attttcagaa gatgagtatg
    24361 cctgtgcatt tttattgcca aaagagagtt ttttaaaaga tttgactcat ccagaagatt
    24421 tagattatta tgtagaacta aagaaaaaat ggattgtacc tatatctgct atgattttta
    24481 gagcatataa tctagaaaag ataaattaca aaaaatacaa ttatcttatg aatgaaatgg
    24541 ataaaaaagg ctggttgata gaagaaccac tagacaaaat gaaaggttca agcccaacgt
    24601 atttaaaaag agcagttgaa ttattgatag aaaataaaat aatgagtgta aatagtatag
    24661 tatcaagttt agaggaattt ggaataaatc tttatccaga agacttagaa ttattgatgg
    24721 gattgaaaaa aggattgtta tctcaagagg taaataaaaa aagtaaagtt ataaaatttg
    24781 atggtaaaaa ataggtttat attttagtat taaaattaaa agcaggtaca aatgatttaa
    24841 acattaactt agttaaaagt cttttcaata agtcatttac ctgcttttag tgtaagaaag
    24901 aatattgaat ctaaagtgtt tttgaaagtg caatatattc ccttaaaaca gaacaagatt
    24961 tattaaattc gttttgctca tattcagtca tattgatttc aataatttct tcaataccat
    25021 cttttcctat aacacatgga acacctgcaa atacatttct ttcgttatat tgaccttcta
    25081 gtaatgtaga aactggaaga acttttttct cattgtgtag tatagctttt acaatttcta
    25141 ctaaagcagt acctatacca aattctgtac aatctttacc atttattata cttattcctg
    25201 tttttttatt tttttcaact attgatggta agtctaaatt gctataagta cttgggttgt
    25261 cttttatcat gtctaagatt ggtttaccac caattgaaac atgagaccaa ggaaccattt
    25321 gagaatctcc atgttcaccc atagaataag cttgaattga ttgttgagcg attccagttt
    25381 cttcagataa aatccttcta agtcttgttg aatctaaagc tgttccagtt ccaatgactt
    25441 tgtttttagg aaagccagat ttttcccaaa tataatttgt aactacatca acaggattag
    25501 atatgactac aaatatacca tcaaagccag aatcaactat gggttttact atagatttta
    25561 tcattccaat agttggtctt agtaaatcta atctagttgt gttttgtcta cgtaaaggcc
    25621 cttctgaaga gtctgcaaca cttatcacta ctatgtcaga atctttacag tcagaaaaag
    25681 ttcctttttc tatatgtact ttatgtggca gatatgaaac tgcatcagct aaatctaaag
    25741 cttgagcttt tgatttagat tcatctatat caatcataaa gagttcatca caaactcctt
    25801 gagttattaa actaaatcca caatgagaac caacatgccc tgaacctaca atagatattt
    25861 ttcttggctt tattgccatt ttaaatcact ccccctaaaa taacgataca ttgaaaatta
    25921 tagatgttat taaaagctgt ttttggatat tttaatattc tattatttca gaaaatttat
    25981 ttaatatgat tttatactaa aatttttaaa aaagcaatgt taatatactc tctattagtg
    26041 aatattaaag tattatatgt atattaataa ttattaaaat atgtaatgtc actgatagtt
    26101 agaatattta agtgctaaaa gatgtgtata aataataatg atgtcagttt ataatgatat
    26161 taaattgaga tatactgttt ctctaaatta aaaaataaag gagtaaatgt gttatgaatt
    26221 atcatacaaa agaagaattg gtggaagcac tgagagtagt atcttcaagt attattaatt
    26281 gtggaaaagg acagaagaaa ttttctgagg agacatctca tcatacacgt tttaagaata
    26341 ttatagaagt aatgtatatt tcaaaatcat taataatgga tgaaattagt aaaagagatt
    26401 gaagcttatt ttgcaattta acatgtttta atatacattt tattatataa gaaaataagt
    26461 aaacatacat gttataaaat attggaataa tatacaatta taaatttgtt aacactaata
    26521 tctatatgtt aaaatatagt agaagatgtt agtaaataat aggatgagtt ctattttaat
    26581 acaattaaat taagcttagt ttgaaatttg tatctaaaaa gtaaagtaat ctagaattaa
    26641 gaaaatggag atagaattat aatggaaaag ttatattata caaatcagta tataagagat
    26701 tttacagcag aaataattga aataaaagaa gtagaaaata agtatcatgt tttattagat
    26761 aagacagctt tttttcctgg tggaggaggt cagtttggag acctgggaaa aatagagagt
    26821 gatgatgtaa taaatgtgta tgaagatgga aaaaaaatat accatgtatt agataaaaaa
    26881 cctataaaga tacataaggt aaagtgtagt attgattggg atagaagaga agatggaatg
    26941 catcaacatt ttggacaaca tgtattgtct ggatgttttt ttaaaacttt taatgcaaat
    27001 acgacaggtt ttcatttggg aaatgagtat agtacagtag atatagaagg taatttagaa
    27061 gaggataaaa ttagagagat agagttgttt gccaatgaaa ttattcgtca aaatatacaa
    27121 gtagagacat tacttccaac gaaaaaagaa ctaaaaaaga tttggttaag acgtgatttg
    27181 ccaaatactg atgaagagat aagagtaata aaaataggtg atttagatac gaatgcatgt
    27241 tgtggagtgc atccaaaatc aactggtgaa ttgagaatga taaaaataaa gaaatgggaa
    27301 aaacataagt caagtacaag aatagagttt ctagcaggta aaagggcagt ggatgaagta
    27361 ttgaagaggg atatatattt gactaaaata tgtagatatt taagctgtag tgaggaagat
    27421 gctataaatg gtattgtaaa tctaaatagt aaagtggaag aggctttaat taaaaaaaga
    27481 aggcttgaag aagtagtatc tacatatcag gtcaaagaaa tgattgaaaa agcaaataag
    27541 gttggcaata tttcggtcat taaaaaaatt tatgatgatg aagatttgaa atatgtaaat
    27601 aagatagcaa ataaaattgc agaatatgaa aatagtattg cattattagc tgttaaattt
    27661 aatgataaaa taaatttagt ttttgcatgt tctaaaaatt taaaagatat taatatggga
    27721 gttttattaa aggatgcaat aagtcttata gatggcaagg gtggtggaag taaagtatta
    27781 gctcaaggag gaggtaagaa taatggaaat ttagaggcta cacttgatta tgcatttatg
    27841 aagatagaaa aaactctata aatatattat ataaaaaacc ttagtagata aaatagatat
    27901 ggaggaataa gtatggagca acaaaaggac tacatagagt tatatgaaaa tgaagaacta
    27961 atagagataa gagaagcacg tatggatgat ttggatacaa tagcaaaatt taattataat
    28021 ttggctaaag aaactgaagg aaaagaactt gatatggatg ttttaactaa aggtgtaaaa
    28081 gcattgttat tagatgagag aaaaggaaaa tatcatgtat atacagtatt tgataaagtt
    28141 gttgcacaga ttatgtatac atatgagtgg agtgattgga gaaatggaaa tttcctttgg
    28201 attcagagtg tatatgtaga taaggaatat agaagaaaag gtatctttaa ttatttattt
    28261 aattatataa aaaatatatg tgataaagat gaaaatatag ttggaatgag attatatgta
    28321 gaaaaagaaa acataaatgc aaaagcaaca tatgagtctt taaatatgta tgagtgtgat
    28381 tataatatgt atgaatacga agtaatacat tcgtaatata aatttgtaat actgttatac
    28441 tgatgttata aagtattgat tatattgacg attatatgaa ataaactgga tattataatt
    28501 agaattttta gggggtataa aaatgggcgt tttaaaagga atgttttatg tatttttatt
    28561 tttagactta gtgtcaatat tctgtttctt tttcaataaa ggaaaaatag catctaataa
    28621 aattgtgttt aatgcaatag gagtacttac atttgtactt tgttttatgc tttttagtta
    28681 ttatcctaat aataatctta ttggaaaatt tattgcttct ctatttttta tatttggagt
    28741 tgcaggagtt atgttgaaag aaaaaaattt tttatatgct agacttcttt taactgtagt
    28801 tatagttttt tctacattaa gattgttcgt tattcaataa aatgtatttg tatgaaaatt
    28861 tattaaagtc tacacattta agtgtaggct tttttgattt tttgtttgaa aattaaggaa
    28921 attttaagga aattttaaaa tcgtcttaaa tatttattga tatacttaaa atattaatag
    28981 cgaaaggaga cttatcagtg atagaaagta aaaagtcaga aaaattgtta ctgtcaatta
    29041 tatacataat atttttggta tatattttaa tgattataag aataatttta tttagagatg
    29101 taccaattta cgctattttc aagggaacgt ttaggaatgt aaatttaatt ccattttata
    29161 caatatatca atttatagta gatagtaatc ttgactttat gaaagctact gtaaatatta
    29221 tagaaaatat aggtatattt attcctatgg gaattttttt acctatagta tgtaaaaatc
    29281 taaataaaaa aactataatt atagtaatta tacttgttag cctagcattt gaattaacac
    29341 aatatatttt tgctcttgga agtagtgata tagatgatgt tattttaaat tcattaggtg
    29401 gcataattgg aattaatatt tacataaaca tgaataaatt atttcccaat gatattaaca
    29461 gatttaaggc tataataggt actagtttag ttttaggagt tataggatta ggagttattt
    29521 ctaaaaatta tcataactta ctaactttta aatttagacc tgatagaaaa atatcaaaaa
    29581 tattaattga agaaaatagg gaaataatta aagatataaa taaagataca gtagatatag
    29641 ttgggacatt tgagagcttt aaaaaaggaa taataactat taaagcaggt tctaataaca
    29701 aagtaaagag accagagaat ttaattgatt ctgatggaaa tataagaatt tatttaaatg
    29761 aaaatacaaa attagtatct tatataatta ccaaagaatc aaaaatggat atagttaaat
    29821 atgaggaatt tgatgtgaag aatttagatt tattaaggag atatgatact attaatgttt
    29881 ggattgataa agaaaatcag ccaaaggata aacatggtat tatggctagt aaattattaa
    29941 ttggattgta tgaataaaat attaaacaag aataaaagaa taacaaatat aaaaaacgaa
    30001 aaaactattt ctataattat ttttacgttg tgcataaaat aagaacatta gtgaaggagt
    30061 agagataaat tatggagata ataaaatata tcttgtactt ttttatatat tcatttttag
    30121 gatggacagt agaaagtata ggatgttcta tagcaagcaa aagaataatc aacagaggtt
    30181 ttttaaatgg tccaatatgc cctgtttatg gttttggagc ggtaattgtg atatcactat
    30241 tgggaagatt taataatgta gtaatagtat ttctattagg aatgatttta actacgatac
    30301 tagaatattt tacaggattt attttagaaa ccttatttca tgctaaatgg tgggattatt
    30361 ctgacaaaaa attcaatata aagggtagag tatgtttaaa aaatgcaata tactttggtg
    30421 taatgtctgt tttaataata agatttatac atccatttat aaaatatttt gtaagtataa
    30481 ttccatatag aatattaatt tcaatggcta taattacaac actttggact atacttgatt
    30541 tgattgttac tattataaca cttaaaaaat tagatataaa gttaaactta ttagacgata
    30601 taattacaga ccttaatgat ataaatgtga aattggataa atttgataga ggagaaatac
    30661 aagctttatt taaaacaata aataacgacg aattagaagt tagagaaaaa ataaacaaaa
    30721 taaatagtaa gttggaccgt atagagtcta atattatttt acaaaaaaga gttataaaag
    30781 cttttccaca tataaaacat aaaaaacaac aagagcaact agaacatttt aaaaaaatta
    30841 ttaatgagaa aaggtaatta tacaatttaa tgaagacgaa tagaataatg gtatttataa
    30901 gatgattttc agaggactct ataaaaatag aatagagtcc tttatttttt gaaaaataat
    30961 gtttatttga taaaaataaa atatattgtt tctgaataac aaatattttg aaaattataa
    31021 aaacatatat tgacaatttg tgtcaaaaat actaacatta agtatataaa gaattttata
    31081 tgagaatatc tttataaatc gcaataattt taaaacataa atttatttaa agaggggatg
    31141 atttgccaat gagcgagata actagtcaaa tgataagtac agaagaaaaa aaatatgttg
    31201 ctaaaactca aaagatacct tattatccag tagcatttaa atcaggtgat ggtgcaatgc
    31261 tatatgatta tgaaggtaat gaatatgtag attttttagc aagtgcaggc tctgcaaatg
    31321 taggtcatgg taataaggaa atctcacaag cagttaaaga acaaatggat gatataacac
    31381 aatatacact tgcatatttc catagtgatc ctcctgtaaa attagctgag aagcttgtgg
    31441 aaatagcccc tggagataat gataaaaaag tactatacag tgcaactggt tctgcttgta
    31501 tagatgctgc tataaaatta gcaagagggt atactggaag aacaaagata atatctatgt
    31561 gtgaatctta tcatggaagt acttatggag ctatatctat atctgcttta agtacaaata
    31621 tgagaagaaa aatgggtcca ttgttaccag aagtttatca cttccattat cctgataaaa
    31681 atagaacagc taaagaatgt ttagatgaga tagaatatgc ttttgcacac tatctaccag
    31741 cagaagaggt agctgcaata tttatagagc caattgcagg agatgcagga ataatagtgc
    31801 ctccagtaga gtgggtacaa ggtttaagta aaatatgtaa agaaaatgga atattacttg
    31861 taagtgatga aatacaacaa ggtatgggaa gaacaggtaa gtggtttggt atagaaaatt
    31921 ttggtgttga agcagacctt atagttcttg gaaaatctgt tggaggtgga ttacctctag
    31981 gagcagttgt tggaagaaca gaaataatgc aaagtcttga tgcaccagca catttattta
    32041 ctttagctgg aaacacaaca gtatgtgtgg ctgctttaaa atctatagag ataattgaaa
    32101 aagaaaactt acttcaaaag agtatagaaa tgggagatta tattaaagca ggatttgaaa
    32161 aactaaaaga aaaatacgat ataattggag aaataagagg cataggatta tctataggag
    32221 ttgatatagt taaaggaaaa ggttctaatg aaaaacatcc agatgctaca gctaagatat
    32281 gttatagatg tatacaaact ggattaataa tgatattctt aggacaatct actttaagag
    32341 tgcaaccacc tctagtaata actaaggagc aagtagataa agcaatgaat atcatagatt
    32401 ctgcaataga tgattattta aatggtagaa ttggtgatga agtatatgaa gtaactcaag
    32461 gttggtaaaa taaatattaa atgaaaatag gagttatctc aattttagaa aattatttct
    32521 gaaaagagat aactctttta agttacccac aaataagaaa attgtttgat tcattaaaga
    32581 ctatatttcg gatgtcgttt ttgtgagtat cagagacagt attacgagaa taattacctt
    32641 tattcgtact atctgttaat ttagttataa ttaagatagc taaaagaata agaattactg
    32701 tgtataaagc aataacatat ggttttcttt tatatttgta tttgttattg aaaaaagaat
    32761 ggccataatt atttttattt actttagatg tatttgtatt ctttttcttg ttacctttct
    32821 ttttatcatc cttttttcta tttttagggt aaggaatgac tttgtgtgta ttatcaagtt
    32881 tgatattttt atttttttga atattgtttt ccaggctagc ttttttttct ccaaattgaa
    32941 tagttttatt ggtattgttg ttatctttca atgttaatct ccctccctta aactttccct
    33001 ttagataata ttactactaa cctatggaat atacaataaa taatatataa gtaataaaat
    33061 tttataggta taaatctctt tctccacgct ctaaggcagt catattgtta gatactatgt
    33121 ttcttatatc ttctctttct atcttaccta tttcttctgc gataagtttt ttacccataa
    33181 ttttaagttc ttcatctcca taatcgatta aaaattcatt taatgtagta agagcatttg
    33241 gtgtacatac attatggatt tgtcgacttt tagctaagct catgaatcta tcgccagttc
    33301 tacctttacg ataacaagct gtacaataac taggtatata tccatcagta atcagttctt
    33361 taagcacctc aacagggctt ctatggtctc caacttcgaa ttgttctgta ttgtcaccat
    33421 cttcatatgc tttatatcct ccaacacctg ttagagaacc tgcactaatt tgtgatacac
    33481 catattttag taactcattt ctcatttcag cagtttctct agtggacatt atgattccag
    33541 taaaaggaac agctaatcta gttatagcta ctattttttt gaacatatcg tcagaaacta
    33601 agtgaggaaa atcttctaag ctcatacctt cagctttttt caatctaggg aaagatatag
    33661 tatggaaacc tacaccaaat ttttcctcta agtgttcgtt gtgcatcata agtcctagaa
    33721 cttcaaattt agggtcagat aaaccaaata aaactcctgc accaacatca tcaacaccag
    33781 cttccatagc tctatcaaaa gctgttaaat ggtaataata gtcatttttt atagattgac
    33841 catgcatttt tataaatgtt ggtttgtgat aagtttcttg gaataatata taagttccta
    33901 ttcctttttc ttttagtaat ttatactcat ctacacttgt agctgctatg ttaacgttta
    33961 cccttcttat atttccgttt tcattatatg ttgaataaat tgcatctaag caatctaaga
    34021 tgtaatttat atcacaattt ttagggtctt caccagcttc tagagcaagt cttttatgac
    34081 ccattttttc taatatttta acctcttccc ttatctcttc catggtaagt ttttttcttt
    34141 taaatttgtt gcatttacta aaaccgcaat aaacacattc atttacacag tagtttgata
    34201 cataaagagg ggcaaataaa accactctat taccatatat ttcatttttt atttgcccag
    34261 ctatactaaa taatctatct agttgttttt tatcttctac ttcaagaagt gtagctatat
    34321 ctttataact aagtttttcc cttctatcag ccttatcaag taccttttca atatcatcag
    34381 aagttgaatt ttttgcatct tctaataaag aattaataag ttcatggttt atgaacattt
    34441 acaaacgcct ccattcaata ttatcaccgc gagaatagtc aacttcaagt cctaatgact
    34501 tgatgttttc ttctaaactt tggtgatatt cacaagcttc ttgaccagta aaggctttgt
    34561 tatcgtaaag agaatattgt tttctaaatt cttgaggaga aaggtttggc ataattacat
    34621 tgcaaccagc taaaagacct gcatttctac cactagggtt tatagatgcc aaggctgttg
    34681 tagcgggtaa taaaactttt ggaagtagaa gtcttgtaat tgaaagcata agtaatgtct
    34741 tctctaaatc tccatgttta taatccttaa aaattgtatc atggtgtgga atgaaaggtc
    34801 ctattccaac catatgagga tttaactctt ttaggtataa taaatcacga acaaggtctt
    34861 cgttgttctg aaatggtgat tcaaccataa atccagcacc tacctgataa ccaatttctt
    34921 taaggttttt taggcattct tttctagttc taagctcaat gtttggcgga tgtaattttt
    34981 tataatgact gtctgtagca gtttcatgtc ttaaaagata tctatctgca ccacataaaa
    35041 agtatttttt atacgaatca taactctttt ctcctagtga tagagttatg gcacaatcct
    35101 catatttatt ttttatactt gaaacaattt cacatatttt atcatcagta aaatatgcat
    35161 cttcaccacc ttgcaaaacg aatgttctgt atcctatttt ataacctata tcacaacatt
    35221 caagtatttc atcaagtgaa agcctgtatc ttatgatatt tttattagaa gattgtattc
    35281 cacaatagta gcaattattt ttacaatagt ttgtaagctc tataagtcct ctcaagtaga
    35341 ctctatttcc ataatgttta tttctcatgt cgctagcttg tttataaaga tagtttctta
    35401 aattttgttc gaagttatat tcctcattgt cgatattttc tattaaatat agtagttcat
    35461 caaaacttaa tgaattaatg ctgtaaagtt tatctataaa gtatttaatc ttatttttag
    35521 tcatattcaa atatataatt attaagtata gttaaatttt taataattga aaagttcaag
    35581 tgatctttcc aaaatacctt ttacatatgc tattaagata ccatagttta caataggtac
    35641 attgaaagat tttgcctttt ctattctaga taacattcca gctctattca tcatacaagc
    35701 tccacagtga actacaaggg catatttatt tatatcttca gtgaaggata ctccagaact
    35761 aaattcaaaa gtaatgtttt tgccagtttt ctttctaatc atattaggaa tttttactgt
    35821 tccaatatca tcagtttgtc tatgatgggt acatccttcg gccatcaaga ttttatcacc
    35881 atcttttaaa ttttctaaag cataagcgcc attaatcaat tctttaaggt ctcccttttg
    35941 tctagcaaac aatatagaaa aagatgtaag aggaatatct tttggtgtat ctttatctac
    36001 ttgtggaaat acttgagagt cagtaataac aagttttggt tttttgccta aattagatag
    36061 agtttctttt aaactatctt cttttgtaac tatagaaatt gcaccactat ccaaaatatc
    36121 tcttataact tgctgttgag gaagtataag tctacctttt ggagctgctt tatctattgg
    36181 aacaactaaa acaattaaat catttggttc aattaaatct gataccaatt tgaactcagt
    36241 gctatcctta ggcaaaactt ttattatttc attttttaaa ttttcaattc caattttatc
    36301 tgttgatgag acagaaacaa ctggacattt aactttattt ttagttaagt ttaaaatttc
    36361 tgattgattc ttaatagtat caattttgtt gagaattaga atatgaggga tattcttatc
    36421 attaaacttt tcaattagtg acaaatcttc ttgtgatata ccaatctggc aatccactac
    36481 tagtaaagct atgtctgtct tttctaaaac atctagtgat ttacctattc taagttcacc
    36541 aagttcacca acatcatcaa gaccagcagt atctataaga acacaaggtc ctataggaag
    36601 gatttccatt ggtctaaata ctgggtctgt agtagttcca gcaatatctg agactattgc
    36661 agcactttga tttgttatag catttattat gctagattta cctgcatttc ttttaccaaa
    36721 gagacctata tgtactctta ccgattgtgg agtagaattt agactcattt gtactcacca
    36781 ccttaaactt ctttttttga tatactagtt tttacagata catgaggtat gttgcccaat
    36841 ttaccagtca aactattaat agtatccatt tcgccaacaa ctgctataca tacgattgag
    36901 acaccttctt cttcgcaagg aatgcccatt cttcctttaa taataccttt aaaacctgat
    36961 acaacctcat tgaatttaaa ttgacattct tttggctctt ccaaaatagc acttataact
    37021 gcaacctttt tcataaatat cctcctaact cagaaaatat gtcttaaaca aatccaaaat
    37081 caaaaaactt ttctttgtaa agaaaagttt ctacaaaaga aaagttatta attacacaag
    37141 tataatgtgc tatattaaac tatttcctta cagattagat aactcttttc tggtagggtt
    37201 agcttgtaaa aatttaattt aacaacaagt aactgaagaa aatttttata caatttatat
    37261 aaattataat aaaaattaac taaagaaaat tgaagttact tatataatag tagtaaattg
    37321 aaattaagtc tatagaaaaa ccaatttttg tataaaaata aaaattaaag ttaattattt
    37381 gttaagaatt gactttggta aaatatataa ttaattattc tttaagcata taatttataa
    37441 gtaattttag tgtattttca atagcttcta tatgtgttct ttcataatgg tgactattgt
    37501 ttgttccagg accaacacat gctatttgaa catcttctcc ccaacgaata gcttctgaag
    37561 catctgaacc atagaaagta aatacatcga cagcgtagtc taaattattg tcttctgcaa
    37621 catcaacaag cttgtttctt aaattaaaat catataatga taaattatct tttgcaacta
    37681 tagttacacc atgttcacta gatgtttgac ttggtccagt aggtgctata tctattgcta
    37741 caaattcttt tgttttttca ggtaaacatt tagaaacacc atgtccaatt tcttcataat
    37801 tacttatata aaagttagta gtatgcttag gtgttaaatt gttttcttta aaatatctac
    37861 atatttcaag aaccattgct acagctgatt tattatctat atatctagat tttataaaac
    37921 cagattctgt agcctcaaat ctatggtcta ggcatacaaa atccccaaca cttattccta
    37981 aatctaatac atcttgcttt gtaaatactt tttcatcaag tctaataatc attgtttctt
    38041 catttctttc agtggcagct tttgtttgac catatatatg agtagaagca tacttaaata
    38101 caacacttcc tctgattttt ttaccttttc tagttataac agtacagttt tctccctcta
    38161 tagctgccca acatccacca ccaactttat ggtatttaag agtaccatca gatgatattt
    38221 cttttactat agctccaagt gtatccatat gtgcagatat tgttatttga tttgaatcat
    38281 cttcaccagg aagagtagct ataagtgcac ctttttttgt aagaatagtg tcaagaccta
    38341 aattttcaaa atcttttttg atttctaaaa ctgcattttc agtatatcca gctgggcttg
    38401 gaatgtccaa atattttttc attaaattta tagtattagt taaatttaaa ttcatattgt
    38461 ttcctcctaa ataaatatat ttatacaaat tataacataa atacaaatgt tctgaaaact
    38521 aaaattaaaa gaatagaatc taaacatatt taaaaaaaaa gtatataaaa taaatttgat
    38581 ttatattata tagatttaaa gtaaaaatag ttttatttaa taattaataa aaataaatac
    38641 aaaacaaaat aaataaataa taaaatattt agtttaatta tctttacaaa taaaaatttt
    38701 agtaataaaa taattgttga aaaagatttt aaattcagat tattcatttc taaagtaatt
    38761 aatgtgcaaa
//
LOCUS       DAEPHU010000036        38590 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 01A10CD0081
            SAMN05941466-rid12468953.denovo.036, whole genome shotgun sequence.
ACCESSION   DAEPHU010000036 DAEPHU010000000
VERSION     DAEPHU010000036.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941466
            Sequence Read Archive: SRR6291087
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 38590)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 38590)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068158.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 22:43:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,892
            CDSs (total)                      :: 3,805
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 87
            rRNAs                             :: 8, 1, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 55
            CDSs (without protein)            :: 55
            Pseudo Genes (ambiguous residues) :: 0 of 55
            Pseudo Genes (frameshifted)       :: 21 of 55
            Pseudo Genes (incomplete)         :: 28 of 55
            Pseudo Genes (internal stop)      :: 16 of 55
            Pseudo Genes (multiple problems)  :: 8 of 55
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..38590
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941466-rid12468953.denovo.036"
                     /strain="01A10CD0081"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            complement(<1..896)
                     /locus_tag="KR231_001934"
     CDS             complement(<1..896)
                     /locus_tag="KR231_001934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009243519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional lysozyme/C40 family peptidase"
                     /protein_id="HBH0004311.1"
                     /translation="MKLKHIAIIGSLFPILFSIVLFFGVLMSADSDDENSNFSSGITG
                     MNLSAEVLKHQPMVEKYAKEYGISEYVNVLLAIIQVESGGTAKDVMQSSESLGLPPNS
                     LDTESSIKQGCKYFASLLSSCKNQGINDLNVAIQSYNYGGGYVGYVAGKGKKHTFNLA
                     ESFAREKSGGKKVTYTNPIAVAKNGGWRYGYGNMFYVELVNQYLTVPQVSGELAQKVM
                     NEALKYQGWKYVYGGSNPNTSFDCSGLTQWCYGKAGISLPRTAQMQYDATQHIPLSQA
                     KAGELVFFHSTYNAGSYVTHVG"
     gene            complement(893..3085)
                     /locus_tag="KR231_001935"
     CDS             complement(893..3085)
                     /locus_tag="KR231_001935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HBH0004312.1"
                     /translation="MKERIQSAFTKKKIFHFLKMALFVVALSLILLSLLGTVAHATGL
                     VDDTINAENLYSKYPLSNYQLDFYVDNSWAWLPWNWLDGIGKSVQYGLYCITNFVWTI
                     SLYLSNATGYVVQEAYKLDFINDMADSIGQSIQTLAGVTSSGFSTSGFYVGFLLLIIL
                     VVGLYVAYTGLIKRETSKALHAVINFVVVFILSASFIAYAPDYIKKINEFSSDISTAS
                     LDLGTKIMLPNSDSEGKDSVDLIRDSLFSIQVEQPWLLLQFGNSNAEEIGTDRVEALV
                     SASPENEDGKTREEVVKTEIESNDNNNLTIPQVVNRLGMVFFLLFFNLGITIFVFLLT
                     GMMLFSQILFIIFAMFLPISFLLSMIPSYESMAKQAIVRVFNTIMTRAGITLIVTVAF
                     SISSMFYNISTDYPFFMVAFLQIVCFAGIYMKLGDLMSMFSLNANDSQSMGRRIFRRP
                     YLYMAHRARRMERRLAGAVTAGGVAGAVAGSTVSNARTTRNNSAKDNRGNTSSSMGQR
                     AGSKVGAVLDTKNKVKDKANAMKETVKDIPTQTAYAVHSAKEKAKTSVSDFKRGMVQE
                     QQSRQSGRLEKQEQHKKNIADKRMELQKAQEARQARKTDGSATTGATRPHERPVTASA
                     IPKTNVEKTQEVKRPATTSTSKAGEPVKTNSVKERPLSSGTSDGKIPQSAQTVHSKNV
                     EKVVSHETHQNYKAERTTKAQTVEQAKRTTEHTEKNRNLVTKKGQKKK"
     gene            complement(3085..5535)
                     /locus_tag="KR231_001936"
     CDS             complement(3085..5535)
                     /locus_tag="KR231_001936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HBH0004313.1"
                     /translation="MFPIKYIDNNLVWNKDNEVFAYYELIPYNYSFLSAEQKFIVHDS
                     FRQLIAQSREGKIHALQIATESSIRSMQEQSKRLVTGKLKEVAYQKIDEQTEALVSMI
                     GDNQVDYRFFLGFKLMVTEEQLNLKNLKKSAWLTFKEFLHEVNHTLMNDFVSMPNDEI
                     NRYMKMEKLLENKISRRFKVRRLEINDFGYLMEHLYGRDGIAYEDYEHQLPKKKYKKE
                     TLIKYYDLIRPTRCVIEESQRYLRLEHEDKESYVSYFTVNAIVGELDFPSSEIFYFQQ
                     QQFTFPVDTSMNVEIVENRKALTTVRNKKKELKDLDNHAYQAGSETSSNVVDALDSVD
                     ELETDLDQTKESMYKLSYVIRVSADDLDELKRRCDEVKDFYDDLNVKLVRPAGDMLGL
                     HSEFLPASKRYINDYVQYVKSDFLAGLGFGATQQLGENTGIYMGYSVDTGRNVYLQPS
                     LASQGVKGTVTNALASAFVGSLGGGKSFCNNLLVYYSVLFGGQAVILDPKSERGNWKE
                     TLPEIAHEINIVNLTSDKDNAGLLDPFVIMKNVKDAESLAIDILTFLTGISSRDGEKF
                     PVLRKAVRSVTQSETRGLLHVIDELRCEDTAISRNIADHIDSFTDYDFAHLLFSDGTV
                     ENAISLDNQLNIIQVADLVLPDKDTTFEEYTTIELLSVSMLIVISTFALDFIHSDRSI
                     FKIVDLDEAWAFLNVAQGEILSNKLVRAGRAMQAGVYFVTQSSGDVSKESLKNNIGLK
                     FAFRSTDINEIKQTLEFFGIDKEDENNQKRLRDLENGQCLLQDLYGRVGVVQIHPVFE
                     ELLHAFDTRPPIQRNEVE"
     gene            complement(5522..5911)
                     /locus_tag="KR231_001937"
     CDS             complement(5522..5911)
                     /locus_tag="KR231_001937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009274602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HBH0004314.1"
                     /translation="MKKIRSYTGIWNVEKVLYAINDFNLPFPVTFTQITWFVITEFII
                     ILFGDMPPLSMIEGAFLKYFGIPAFLTWFMSQKTFDGKKPYSFLKSQITYALRPKITY
                     AGKAVKLQKEIFNETITAVRSVSYVPD"
     gene            complement(6029..6532)
                     /locus_tag="KR231_001938"
     CDS             complement(6029..6532)
                     /locus_tag="KR231_001938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004843360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antirestriction protein ArdA"
                     /protein_id="HBH0004315.1"
                     /translation="MIDDMAVYIANLGKYNEGYLVGAWFTFPIDEEDVKEKIGLNEQY
                     EEYAIHDTDNFPIEIGEYVSIDELNEMYEMIEELPDYIVDCLDEFIGHYGTLEEVVEH
                     KDDIYYYPDCETMTDVAYYYIDELQALGDIPPSLQNYIDYEAYGRDLDMGGCFIATSR
                     GMCEIPY"
     gene            complement(6535..7038)
                     /locus_tag="KR231_001939"
     CDS             complement(6535..7038)
                     /locus_tag="KR231_001939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004843359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antirestriction protein ArdA"
                     /protein_id="HBH0004316.1"
                     /translation="MQETRVLVETKRTTGEETTSYWFDLPIEVAEFEEKLGVSTESQD
                     YRIIEKLLPYADEVHEHTSVYQLNELDYMYRQLSSDMQEEYTMLHTVYENLEALYICR
                     NVITLYPDCKSMIDVARQKLMNDPTFKHLSEDCQEYYFDFETYASHLQEHGKFLVTEH
                     GIFELPE"
     gene            complement(6957..7253)
                     /locus_tag="KR231_001940"
     CDS             complement(6957..7253)
                     /locus_tag="KR231_001940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005339688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HBH0004317.1"
                     /translation="MNDIFRDMQAKVGCENISDLPSYKRKVWHEMKQLNLADYEEKQL
                     EDFSKYVFGMSCQTLKDVMKQQKGREEQCRKQGYWWKRKEQLAKKQHHTGSTCR"
     gene            complement(7350..7952)
                     /locus_tag="KR231_001941"
     CDS             complement(7350..7952)
                     /locus_tag="KR231_001941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437218.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HBH0004318.1"
                     /translation="MDKVVIYIHGKGGNAEESSHYKPLFSDCDVVGLNYTAQYPWEAK
                     EEFPSLFDLICKHYKSVQIVANSIGAYFAMNALSDKQIEKAYFISPIVNMEKLIADMM
                     YWANVTEDELRDKKEIKTTFGETLSWEYLCYVKENPTTWKIPTNILFGEKDNLTSYAT
                     ISEFTKQTNATLTVMRNGEHWFHTEEQMKFLDEWINKSAR"
     gene            complement(8037..8198)
                     /locus_tag="KR231_001942"
     CDS             complement(8037..8198)
                     /locus_tag="KR231_001942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0004319.1"
                     /translation="MAIVVIGIYLGFKREFSKLIGFLVVALVAVGLVFNAGGVKDVLL
                     ELFNKIIGA"
     gene            complement(8365..10275)
                     /gene="ltrA"
                     /locus_tag="KR231_001943"
     CDS             complement(8365..10275)
                     /gene="ltrA"
                     /locus_tag="KR231_001943"
                     /EC_number="2.7.7.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
                     /protein_id="HBH0004320.1"
                     /translation="MPKNKNETLCVEDLRHAEYYEMQNTFDDLYAKSKNGDIFTHLMD
                     IILSRENILLAYRNIKANAGSKTAGTDGTIIKDIGKLPAETVVKKVRYIVAGSPHGYR
                     PKPVRRKEIPKPNGKTRPLGIPCMWDRLIQQCIKQVLEPICEAKFSENSYGFRPNRSV
                     ENAIKATYNRLQISQLHYVIEFDIKGFFDNVNHSKLIKQIWAMGIRDKHLIFILKRIL
                     KAPIKMTNGTITYPEKGTPQGGIISPLLANIVLNELDHWVESQWQENPVTKNYVVHIN
                     KSGSPCKSNAYKEMKKTKLKEMYMVRYADDFRVFCRYKESAEKAKIAITQWIEQRLKL
                     EVSQEKTRIVNVRKRYSDFLGFKIKMIPRRKKLVVKSHISDKQFKNQKDKLVSQAKKI
                     ASPSKGKTELEETRLYNSMVLGMQNYYQIATNVNLDCMKLNRAVMAIFTNRLGTNKRG
                     RLRKTGRQLTTKEATRYGKSKMLRYVAGEGEPIFPVGYIQHRKPMAKVYLANCYTLEG
                     RKFIHTNLSVDKLLMYQLMKLSLENRTIEYADNRISLFSAQHGKCAITLEEFQQANEI
                     HCHHIVPTGAGGNDDYKNHILVKEAVHRLIHAKTEETIQKYIALLKLNKVQLIRLNKY
                     RVLAGNQELNLI"
     gene            complement(11017..11151)
                     /locus_tag="KR231_001944"
     CDS             complement(11017..11151)
                     /locus_tag="KR231_001944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017143882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3789 domain-containing protein"
                     /protein_id="HBH0004321.1"
                     /translation="MWELLKDLLLVSFGMGIGVVLMCILTVGKEADRCMEEIKEREDN
                     "
     gene            complement(11159..12358)
                     /locus_tag="KR231_001945"
     CDS             complement(11159..12358)
                     /locus_tag="KR231_001945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
                     /protein_id="HBH0004322.1"
                     /translation="MNETDFLTALKEKRCAYGVSQTRLAIMANISREHLSRIEAGKVT
                     LTEDMKHTLLEAVEKFNPNNPMFLLFDYVRIRFPTMDIKHIIKDILKLNIGYMLHEDY
                     GHYKYTEHYHIGDVFVYVSQDEEKGVLLELKGKGCRQFESYLLAQERSWYDFFTDALV
                     EGGVMKRLDLAINDRTGLLDIPELIRKCENEECISKFRSFKSYGSGELVKHNETDKYG
                     MGHTLYIGSFSSEVYFCCYEKNYEQYAKLGIPIEEVPIKNRFEIRLKNERAYYAVVEL
                     LTHYDAELTAFSIINQYIRFADKEPDKRKSDWKTNVRWAWFIGEGRPPVKLTTQPEPY
                     TLERTLNWLQRQVAPTLKMLKQIDKDNQTEYLETIEKQAKLTERHYQIIKQQTATVEE
                     MVANVKE"
     gene            complement(12560..13954)
                     /locus_tag="KR231_001946"
     CDS             complement(12560..13954)
                     /locus_tag="KR231_001946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008787614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HBH0004323.1"
                     /translation="MKMILNKGHRIRASDKNLVYHFSIGTLLFVFIAVILLLNMKQLM
                     RTDWEHFSLLDNGLTLSTYNFITLLIATGVCALVAFLYYRFCYDSFKKLLHRQKLARM
                     ILENKWYEADTVQDSGFFTDLQSRSREKIIWFPKIYYQMEKGLLHIRCEITLGKYQDQ
                     LLRLEDKLESGLYCELTDKTLHDGYIEYTMLYDMIANRITIDEVKAENGCLRLMKNLV
                     WEYDALPHALIAGGTGGGKTYFLLTLIEALLHTNAVLYILDPKNADLADLGTVMGNVY
                     HTKEEMIDCVNAFYEGMVQRSEEMKRHPDYKTGENYAYLGLPPCFLIFDEYVAFFEML
                     GTKESVSLLSQLKKIVMLGRQAGYFLIVACQRPDAKYFSDGIRDNFNFRVGLGRISEL
                     GYGMLFSSDVKKQFFQKRIKGRGYCDVGTSVISEFYTPLVPKGHDFLQTIGSLAYARQ
                     DGTATCEAKGDGTD"
     gene            complement(14071..14556)
                     /locus_tag="KR231_001947"
     CDS             complement(14071..14556)
                     /locus_tag="KR231_001947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006776881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0004324.1"
                     /translation="MAKEKGSFKEFLSAIAPEHQAFVEKLNTKLIEQGCDLVIKEAKS
                     GYTASYQLEKKTVMNWVFRKTGVFARIYGDNAGKYEDIIASLPADMQKKMTTSRDCKR
                     LIDPNACSDTCVKGFVYALNGDTHKKCRNDGMLFVLTNETAEHIAGLVCAEVNVRKSA
                     L"
     gene            complement(14654..15037)
                     /locus_tag="KR231_001948"
     CDS             complement(14654..15037)
                     /locus_tag="KR231_001948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014080829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HBH0004325.1"
                     /translation="MRLANGIVLDKEKTFGVLKFSALRHEVRAENDDGSTSEEITRRT
                     YDLKCSVQERMIQVSIPADIPVKDYPYNAEVELVNPVADTVANASYRGVNVDWYIKAD
                     DIILKNKGGQVGNPQNHAPQGQPKK"
     gene            complement(15052..15378)
                     /locus_tag="KR231_001949"
     CDS             complement(15052..15378)
                     /locus_tag="KR231_001949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005337695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HBH0004326.1"
                     /translation="MELKYVVPNMAQTFGNLEFAGENKIEQQRINGRFTPVSRSYNLY
                     SDVQRADDIIVTIPAKAGEKHFKPEQRVKLINPKITADGKAVKGRGFTNYILTADDML
                     PAEESK"
     gene            complement(15614..18658)
                     /locus_tag="KR231_001950"
     CDS             complement(15614..18658)
                     /locus_tag="KR231_001950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SrtB-anchored collagen-binding adhesin"
                     /protein_id="HBH0004327.1"
                     /translation="MKKILKRLCTGVLAFATVVTALPTTLVHAESKQYWTESEERVGI
                     VEKVMNDGSIGSTFNEGHLTVEGEDAYCIDINTDFKNGYKTRADASSRMSADQISDVA
                     LSIEYVKQYTDNHNGISKNHAYLLRQLVVWQRLSVHLGWQCDNVRASYDEIPKATQDE
                     VFAGAKAFVKENKGRYECGGYIYSGEGQELGQFWAKLNVGNAKLQKTSNNTSITNGNG
                     NYSIAGATYGVFSDKDCTKQIATLTTDDSGNTEVAEVKATTVYIKELSAPLGYKVDTT
                     VYSLKVEAGKTATLKVSDTPKVTDTLIELFKIDMETQKANPQGNASLEGAEFTWKYYA
                     GFYNKDNLPAEATRTWVTKTTAETDSNGTTHYITKLADAYKVSGDSFYMQDGKAFLPL
                     GTLTVEETKSPTGYLLDGAYMQANGSEEQIKALYLTQITEDGDLAVLTGSNQFSVSDK
                     VIRGGVKIQKRDLETKDTKPQGSATLKDTAFDIISLNDNAVLVEGKIYKKNEVVKTIH
                     TDIEGIASTSADLLPYGNFRIVEKQAPNGYLTDGAKPIDFTITENGKIVDLTDEAHSI
                     YNQIKRGDIEGVKIGAGTHKRLADVPFRITSKTTGESHVVVTDDNGQFSTSSKWASHK
                     HNTNAGKTSEDGVWFGTSEPDDSKGALPYDTYIIEELRSDSNKGMELIPPFEIVVSRN
                     NLVIDLGTLTDEYEKEITIHTTATSKDGEKTILAGKEVTIVDTVKLDGLTKGTKYQLK
                     GWQMLKEENAEIIIDGKRVESDYTFVADDEEMKVEISYTFNASELGGKNLVTFEELYD
                     LSNPDEPMKVAEHKDIEDDGQTVLITERIIKIHTTATDKDGNKELEAGKDVTIIDTVT
                     LEGLEVGTKYKLVGWQMLKEENAELLINGKRVESDYTFIADSETMKVEVTFTFDATSL
                     DGKQLVTFEELYDLSNPNEPKKVTEHKDIEDEGQTITFKEKPEVPEKPETPTTPEKPS
                     RPTDSPKTGDNTNVMAFLVMLLTSAGGLAGTYLYKRRKMKKS"
     gene            19186..20193
                     /gene="asrA"
                     /locus_tag="KR231_001951"
     CDS             19186..20193
                     /gene="asrA"
                     /locus_tag="KR231_001951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic sulfite reductase subunit AsrA"
                     /protein_id="HBH0004328.1"
                     /translation="MKLKLDSSKFNEGLNYLKKDYKIFAPVLIPFKGTFSDTDVIRYK
                     EVNAFEEMEFAKKANFSPKDVVLPINQVLFYFTEKEFKESDLDNKKILIFLRACDING
                     IKRLDEIYLNNGEEKDYFYKNIRDKVKFALVGCKESFRNCFCVSMDSNKTDNYSIGLN
                     IEGDTLYLDIKDSEFEVFNGEATEFNVDYVTDNLISVDVPENIDSNEMIGNSIWDEYD
                     TRCIGCGRCNFVCPTCSCFTMQDIFYKENENVGERRRVWASCQVDGYTDIAGGNSFRK
                     KQGERMRFKTMHKIHDFKKRFGYHMCVGCGRCDDACPQYISFSKCIEKINDLVISKEE
                     V"
     gene            20194..20985
                     /gene="asrB"
                     /locus_tag="KR231_001952"
     CDS             20194..20985
                     /gene="asrB"
                     /locus_tag="KR231_001952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic sulfite reductase subunit AsrB"
                     /protein_id="HBH0004329.1"
                     /translation="MNPYIPVSAKILDIVKHTDKEWTFRVNCNTKGVLPGKFYEISIP
                     KYGESPISVSGYGEDYIDFTIRNVGKVTSELFNYKEGDSFFIRGPYGNGFDVSLYEGR
                     EIVVVAGGSALAPVRGIVEYFYNNKEKCEKFKLIVGFKSPKDILFADDLKRWSKKLDI
                     LVTVDGAEEGYSGNVGLVTKYIPELDMKDINNTSIVVVGPPMMMKFTVEEFLKRDLDE
                     KNIWVSYERKMCCGIGKCGHCKMDDTYICLDGPVFDYSYAKNLID"
     gene            20998..21969
                     /gene="asrC"
                     /locus_tag="KR231_001953"
     CDS             20998..21969
                     /gene="asrC"
                     /locus_tag="KR231_001953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfite reductase subunit C"
                     /protein_id="HBH0004330.1"
                     /translation="MIRDLNTKKVMKNAYRITKTKYETSLRVRVPGGLIDPESLAVVS
                     KIASEYGNGQVHITTRQGFEILGINMEDMEEINKIIQPVIEKMNINQSEKNAGYPAAG
                     TRNIAACIGNKVCPKAQYNTTEFAKRIEKAIFPNDLHFKVALTGCPNDCIKARMNDFG
                     IIGMALPIYEKDRCVNCGACVKKCSKISVGALKTENNKVVRDKDKCIGCGECVLNCPT
                     NAWTRDEKKYYRLAIMGRTGKKNPRLAEDFLLWVDEDSIIKIILNTYRYVEKYIDKDA
                     PGGKEHIGYIIDRTGFMEFKKWALEGVELPEITKMYENIYWSGIKYL"
     gene            22026..22802
                     /locus_tag="KR231_001954"
     CDS             22026..22802
                     /locus_tag="KR231_001954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate/nitrite transporter family protein"
                     /protein_id="HBH0004331.1"
                     /translation="MHKETLDKLTNAAINKINLLNTSKVKYLVSSAFAGLYVGIGILL
                     IFTIGGLLTDAGSPMTKIVMGLSFAIALSLVIMTGTELFTGNNMVMSAGMLNKGVSIK
                     DTSKIWAYSWVGNLIGALVLGIIFVGTGLVDKGPVAEFFANTAASKASMPFTALFFRG
                     ILCNILVCVSVLCSFRTNSDTAKIIMIFLCLFAFITSGFEHSVANMTIYSVSLFSPTI
                     STVTIGGAIYNLVAVTLGNIVGGALFMGLGTYILGKEKLN"
     gene            23073..25091
                     /locus_tag="KR231_001955"
     CDS             23073..25091
                     /locus_tag="KR231_001955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HBH0004332.1"
                     /translation="MTKKLVISKTKLFIFIIAFISIFIYLFGSKNTLIGVGIVTAMLT
                     LLERDLTISPIKNLLKYLAINIILGILSFFAVQNMYLGVLLNFIALFIIGYVFSYDLK
                     RAVYVPFGLMYIFMVSIPVGKSEFPMRLSALAVGAVIIMIAQFVMNRNRMKNVGDKEL
                     ISICDELLEKISLLKNTINDDSSIIKSSMRKIDSCNYRINSISKNLKMVIFDNRKDDF
                     YISIRGIDIMNILFSLERISLILERYKKDSKEFEDEDIKNILEESSINSKSDVLVVAT
                     KEINYIKMCLENKDTITDKEILGFRDYVIAQDTKNINLKEIYSVLENLYEFLVDYKKV
                     KSRDEKKAERKSKIPHEFKRLSIYKKNFNLNSIRFSYAVKIALATAVAGFIMDYFHLR
                     DGRWIMLTVFSLTQPYAENCIQRSRKRIEGTFIGAVIFIVLFSIIKDSTLRSLIVLLA
                     GYINSYVVDYRKLMVCVTVSALGSAVVMGDPNVLTISRISYVALGAIIALIVNKFILP
                     YDAKTGYQHVIEMYKGIVKNIIDEVNKSIENVADVYYIKNLLLIPSLIEDRLMLINAI
                     YKDKHQEDFLENQKLLISNMYNLYINVNKNKIKDEDVEKILRDTNYISNYNVDKYDEG
                     RSVILESIVNTKSLGDKIICLNLLQTLNGVKEMYRISNITKVSIKEAA"
     gene            25306..26163
                     /locus_tag="KR231_001956"
     CDS             25306..26163
                     /locus_tag="KR231_001956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HBH0004333.1"
                     /translation="MSKDVKVKRNKKYDTFSITMELERPLLYDEVENKDDKNNNRKFN
                     IKNKIFKGIGILFVLILLGFFIWINKTYEPQKLAKEALVSNSKVEVTVNENISFTPKG
                     RKVSKGLILYPGAKVEIESYAPLARKIAESGYEVVIVKMPLNLAILGTNKAQKVMDSY
                     NNIEHWVIGGHSLGGVAASNFARDNKLIEGVVFLASYPMGDELKELGKKVISIWGSKD
                     GVVNFKSLVESKQKLPDDTTYVEIEGGNHAQFGDYGKQKGDNDAIISQEKQLNITANS
                     IIKFLKNIS"
     gene            26260..27129
                     /locus_tag="KR231_001957"
     CDS             26260..27129
                     /locus_tag="KR231_001957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM protein"
                     /protein_id="HBH0004334.1"
                     /translation="MEYDMPLYRPPSEAYSLIIQVTLGCSHNKCTFCSMYKSKKFKIK
                     PLEVIKNEIDIFRRYYKHVERIFLADGDALIIPMEKLRDIILYIKEVFPECERITMYG
                     SPKSIEKKSDDELKELRKLGVKMIYLGLESGSNEVLEDIKKGFSSEQLIKVGRKVKKS
                     GIKLSATVIAGLGGTKKTHQHAVDTGKMLGAISPDYVGVLSLMVEPNTELYDLLKAGE
                     FTILEDKAVLQEIKEMIKNIDANEKIVFRSNHASNYANLKGVLPDDKQRLIDEIDYYL
                     SNQKLKREEYRRL"
     gene            complement(27500..28132)
                     /locus_tag="KR231_001958"
     CDS             complement(27500..28132)
                     /locus_tag="KR231_001958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CatB-related O-acetyltransferase"
                     /protein_id="HBH0004335.1"
                     /translation="MTIPSSNKVYPRSNDYQTVYLKNVITRENIEVGDYTIYNDFYND
                     PRDFEKNNVLYHYPINNDKLIIGKFCSIACNAKFLMTSGNHSMKSKSTYTFPIFYEEW
                     KLDINHITDAWDNKGNIIIGNDVWIGYDSIIMSGVNIGDGAIIGTRAVVTNDVPPYSI
                     VGGVPAKIIKKRFNNDTISKLLEIKWWDWPYKKIQSNIKHIQSGNIDKLV"
     gene            complement(28204..28557)
                     /locus_tag="KR231_001959"
     CDS             complement(28204..28557)
                     /locus_tag="KR231_001959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="integrase DNA-binding domain-containing protein"
                     /protein_id="HBH0004336.1"
                     /translation="MSTEKRRDNKDRILRTGESQRKDGRYAYKYVYSFGKPQFVYSWK
                     LVPTDKPPKGKRDDISLRDKEKAIQNDLDDSIDTIGKKMTVCQLYAKKNGLRKNIRLN
                     TKKGRHYLMKILNKE"
     gene            complement(28635..28838)
                     /locus_tag="KR231_001960"
     CDS             complement(28635..28838)
                     /locus_tag="KR231_001960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002262306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excisionase"
                     /protein_id="HBH0004337.1"
                     /translation="MNNTDVPIWEKYTLTIEEASKYFRIGEKKLRKLADENLDSGWVI
                     MNSNRIQIKRKQFEKIVDTLDFI"
     gene            28967..29176
                     /locus_tag="KR231_001961"
     CDS             28967..29176
                     /locus_tag="KR231_001961"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0004338.1"
                     /translation="MVQVTAKQPFQRLFTNHYIVALLIKVMAYSICWLSVSQTYLSTL
                     FSCQRTVGIDLSIKNHNSLWAFIDK"
     gene            complement(29228..29458)
                     /locus_tag="KR231_001962"
     CDS             complement(29228..29458)
                     /locus_tag="KR231_001962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBH0004339.1"
                     /translation="MKPTKEVLPFTIILLAVHGDVNAINGILKHFEHYIIRLSQKTLF
                     DEYGNPYIHVEEETKRMLGTKLITAILRFNLS"
     gene            complement(29460..29867)
                     /locus_tag="KR231_001963"
     CDS             complement(29460..29867)
                     /locus_tag="KR231_001963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HBH0004340.1"
                     /translation="MVDEKTIEHQFDSFCKTVLRNYARDIYDENKRRNDYLVSLESLS
                     LAELSKLSILDDYDSNYICMVSYDYNIRIEDVLMAQAIGKLTKRKQDIILLSFFLNMT
                     NADIATLMDLAENTIHYHKTNALKELKELMEEH"
     gene            complement(30227..30676)
                     /locus_tag="KR231_001964"
     CDS             complement(30227..30676)
                     /locus_tag="KR231_001964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBH0004341.1"
                     /translation="MELIEWNYAYITDLVEFANDKEIAKNLRDNFPHPYREQNARDFV
                     SFCLATPDVKQLSYAIFYQERAIGSISLTFEEDTSINKNAELGYWLARNYWGKGIATN
                     AVKEICKIAFEKYNLNKIHANVYSYNRGSSKVLEKCGFKIEEYCHNS"
     gene            complement(30690..31616)
                     /locus_tag="KR231_001965"
     CDS             complement(30690..31616)
                     /locus_tag="KR231_001965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0004342.1"
                     /translation="MSDILSRITNKIGDKNIVDKLSALSKSDLNSLLLEVFDRQANTL
                     TATDILKSYQLNRFTIPSGIDPEEIHALESKLLRKAFNMDIKTIMLSPSAPLGSCSVF
                     GSVDQYNVVSALRGTETLADPSNMLAIIIADKLKRKEENNTIPIHMATTARVIRAQNF
                     VGKGLYSHFGLYCMVSSGIDTGSYTCEKMLLEKHLNYYKDILSEIENVRFSIILRKRN
                     GYKDNDGFFDRMVETIKLIFPNIELSIHNDDVDNNYYKGINFKLSVKQGNETVEIVDG
                     GFVDWTYQMLGNKKERCLISGIGLERFLVAVS"
     gene            complement(31741..32145)
                     /locus_tag="KR231_001966"
                     /pseudo
     CDS             complement(31741..32145)
                     /locus_tag="KR231_001966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433844.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="oxalate:formate antiporter"
     gene            complement(32295..32915)
                     /locus_tag="KR231_001967"
     CDS             complement(32295..32915)
                     /locus_tag="KR231_001967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HBH0004343.1"
                     /translation="MHLIDFMNEDIKKKLVKKTYKKKETILFAEQENEYVILMIDGIA
                     EAFILNVKGNISTIHLYRSGSFFGEMEQFNDGKKPVEIVAFTDCNVYKLHRDDFLNWL
                     RGDFEATKFLIREISSKLVVNAELIEELSSLSVKERLLRCISLHYYRSELNLLTKKQL
                     ASEVNAPIRSINRAINECVQEHLIAYENKRFSVINQREVLKNLPTT"
     gene            complement(33014..34282)
                     /locus_tag="KR231_001968"
                     /pseudo
     CDS             complement(33014..34282)
                     /locus_tag="KR231_001968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000331151.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
     gene            34374..35189
                     /locus_tag="KR231_001969"
     CDS             34374..35189
                     /locus_tag="KR231_001969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage integrase family protein"
                     /protein_id="HBH0004344.1"
                     /translation="MVKLSDAKSWAIRMSEDGCAYKSIDNYKRSLKASFFMAIQDDCI
                     RKNPFNFQLSDVLEDTTEPKIALTPEQEMGLLSFMESDKTYCKYYDDVVILLETGLRI
                     SELCGLTLELDMKNKAIMVDHQLLSDTKIGYYVEVPKTTQGKREIPMTERAYQSFERI
                     VERRKNAKAEPIIVDGYQNFLFLKQDGLPKQATHYQSMLRALVKKYNKTHEDKLPKIT
                     PHTFRHTLCTNMANKGMSPNILQYIMGHKNITMTLGYYAHGSFSSSRAEMERL"
     gene            35861..36628
                     /locus_tag="KR231_001970"
     CDS             35861..36628
                     /locus_tag="KR231_001970"
                     /EC_number="4.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I 3-dehydroquinate dehydratase"
                     /protein_id="HBH0004345.1"
                     /translation="MKRKVQVKNITIGEGRPKICVPIIGKNKKDIIKEAKELKDACLD
                     IIEWRVDFFENVENIKEVKEVLYELRSYIHDIPLLFTFRSVVEGGEKLISRDYYTTLN
                     KEISNTGLVDLIDVELFMGDEVIDEVVNFAHKKEVKVIISNHDFNKTPKKEEIVSRLC
                     RMQELGADLPKIAVMPQNEKDVLVLLEATNEMFKIYADRPIITMSMSGMGVISRLCGE
                     IFGSALTFGAAKSVSAPGQISFKELNSVLNLLHKSIN"
     gene            complement(36956..37633)
                     /locus_tag="KR231_001971"
     CDS             complement(36956..37633)
                     /locus_tag="KR231_001971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0004346.1"
                     /translation="MIVIEGSDKFKIAKEYIDVEYTLFSKVTFRYEKLKFKDNAELEK
                     IKMFKYKNGYIPNKLNLSFGYGFSSYKKQIIRETVDTLRLTEIFSSENIEDIKFIKDG
                     TKKLEISIEKVVKFKRRKKRNYVCCYCPDMYRDIKLDKESINKIYNRKIKIEREVNIF
                     EDEDVIINKKVLKFPKSWTKNMQKYWLSENKYPIHSTVIDDDRYKCCNVQYTKNRVII
                     LYYIYNH"
     gene            complement(37783..38100)
                     /locus_tag="KR231_001972"
     CDS             complement(37783..38100)
                     /locus_tag="KR231_001972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890395.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBH0004347.1"
                     /translation="MNYIGKRLKEERKKANLTSKEFANMVGVSPWYITQIESGKKNPS
                     LKTFIKFVNILNISADVLIKDITSTGKTYLENDINEELKDLNSRELNLISQIIDIIKK
                     NKI"
     gene            complement(38122..38460)
                     /locus_tag="KR231_001973"
     CDS             complement(38122..38460)
                     /locus_tag="KR231_001973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBH0004348.1"
                     /translation="MANIGKIIGDRIKVYRTKLGYSQEFLAEKAGLHPTYIGQIERAE
                     TNTSINIIMKIATALDIPLELLFANIITTEGVDNSVPLECYEMINKLTEKEQIAMLEL
                     IKCIIKYKEI"
BASE COUNT        12023 a         6810 c         6643 g        13114 t
ORIGIN      
        1 attcccacat gggtaacata cgaaccagcg ttataggttg aatggaaaaa gaccaactcc
       61 ccagcttttg cctgcgataa agggatatgc tgggttgcgt catattgcat ttgtgccgtt
      121 ctcggtaaag agataccagc ttttccataa caccattgcg tcagtcccga acagtcaaag
      181 gaagtgttgg gattgctacc gccatacaca tatttccagc cttgatattt caacgcttca
      241 ttcattacct tttgtgccag ttctcccgat acctgcggaa cagttaaata ctgattgact
      301 aattccacat aaaacatatt tccatagcca taccgccagc ccccattttt cgcaacggct
      361 atcgggttgg tgtaggttac ttttttaccg ccagatttct cacgggcaaa gctctctgca
      421 aggttaaaag tatgtttctt tccttttcct gccacatatc ccacatagcc accgccatag
      481 ttataggact gtatcgccac attcaaatca tttattcctt gatttttgca ggaagaaagc
      541 agggacgcaa aatatttaca cccctgcttg attgagcttt ctgtatctaa cgagttgggc
      601 ggtaaaccaa gactttctga actctgcatg acatcttttg ccgtaccgcc actttctact
      661 tgaatgatag ccagtaacac attcacatac tcagaaatac cgtattcttt agcgtacttt
      721 tccaccatag gctgatgttt caagacttct gcggataaat tcatacccgt aatgcccgaa
      781 gaaaagttgc tgttctcgtc gtcgctgtcc gcactcatca gtaccccaaa gaaaaggact
      841 atggaaaaga ggataggaaa cagactgcca atgatagcga tatgtttcaa tttcattttt
      901 tcttctgtcc tttcttcgtt acaaggttac ggttcttttc agtatgttct gttgtacgct
      961 ttgcttgttc aactgtttgt gcctttgtgg tacgttctgc tttgtaattc tggtgtgttt
     1021 catgcgatac cactttttct acatttttac tatgtactgt ctgtgccgat tgtggaattt
     1081 ttccgtcaga tgtacccgaa gataagggac gttctttcac actatttgtt ttgactggct
     1141 cgcctgcttt ggaagttgaa gttgtagcag gacgtttgac ttcctgtgtt ttctcaacat
     1201 ttgtttttgg aatggctgaa gctgtgactg gtcgctcatg gggacgggta gctcccgttg
     1261 tcgctgatcc gtccgtcttt cgtgcctgcc ttgcttcttg tgctttttga agttccatac
     1321 gcttgtcagc gatattcttc ttatgctgtt cctgcttttc caagcgtccc gactgtctgg
     1381 attgttgttc ctgcaccatg ccacgcttga agtccgatac acttgttttt gctttttcct
     1441 ttgcggaatg gacggcataa gcggtctgtg tcggtatatc cttgaccgtt tctttcatag
     1501 cgtttgcctt gtctttgacc ttattcttcg tatctaagac agcacccacc tttgaaccag
     1561 cacgttgtcc catgctggaa gatgtattcc ctcggttgtc ttttgctgaa ttattccttg
     1621 ttgtccttgc attagaaacc gtactgccag ccaccgcacc agcaacaccg ccagcggtaa
     1681 cagcaccagc aagccgtctt tccatacgcc tagccctatg tgccatataa agatacggtc
     1741 tgcggaaaat tcttcgtccc atgctttgac tgtcgttagc gttcaaagag aacatactca
     1801 ttaaatcgcc taacttcatg tagataccag cgaaacacac tatctgcaag aacgccacca
     1861 taaagaacgg gtagtctgtg gaaatgttat aaaacatact ggaaatgcta aatgccaccg
     1921 ttacaatgag cgtaattcct gcccttgtca ttatggtatt aaataccctc acgattgcct
     1981 gctttgccat gctttcatag ctcggtatca tggatagtaa aaagctgata ggtaaaaaca
     2041 tggcgaagat aataaaaagt atctggctga acaacatcat acccgtaagc aagaatacaa
     2101 atatcgtgat acctaagttg aagaacaaga ggaagaacac catacctaaa cggtttacga
     2161 cttgcggtat cgtcagattg ttgttgtcgt tactttcgat ttctgttttc acgacttcct
     2221 ctctggtttt gccgtcctcg ttctctgggc ttgccgatac aagagcttct acacggtctg
     2281 tcccgatttc ctctgcgttg ctgttcccaa actgtaagag tagccacggc tgttccactt
     2341 gaatagagaa taggctgtcc cttatcaagt ccacgctgtc cttgccctcg ctgtcagagt
     2401 ttgggagcat gatttttgtt cccaagtcca aagaagcggt actgatgtcg cttgaaaatt
     2461 catttatctt tttgatgtag tcgggagcat aggcaataaa tgaagccgac aaaataaaca
     2521 ccacaacaaa gttgataacg gcgtgaagtg ccttgctggt ttctctttta atcagtcccg
     2581 tataggcaac atatagtccc accactaaga taatgagaag caggaaaccg acatagaagc
     2641 cagaggttga aaaaccgctt gaggtaacgc ctgcaagggt ctgtatgctc tgcccgatac
     2701 tgtctgccat atcattgatg aagtccagct tgtaggcttc ctgcactaca tagcccgtgg
     2761 cattacttaa atataaactg atagtccaga caaaattagt gatacagtac aaaccatatt
     2821 gtactgattt tccaatcccg tccagccagt tccacggcaa ccaagcccag ctattatcca
     2881 catagaagtc aagctgatag ttggaaagcg gatatttgga atatagattt tctgcgttta
     2941 tcgtatcgtc cacaagcccc gtcgcatgag ccaccgtccc cagaagtgaa agcaggataa
     3001 gggagagtgc caccacgaac agagccattt tgagaaagtg gaaaatcttc ttttttgtga
     3061 acgcactctg tatcctttct ttcatcactc cacctcattt ctctgtatag gcggtctggt
     3121 atcaaaggcg tgtagcagtt cttcaaagac ggggtgtatc tgtaccacgc cgacacgccc
     3181 gtataagtcc tgcaacaagc attgtccgtt ctccaaatca cgaagtcgct tctgattgtt
     3241 ttcgtcctct ttgtcgatac cgaaaaattc taaagtctgt tttatctcgt tgatgtcagt
     3301 agaacggaaa gcgaatttta agccgatatt gtttttcaga ctttcctttg acacgtcccc
     3361 agaagattgc gtaacgaaat acacacctgc ctgcatagct cgtccagcac gcaccagctt
     3421 gttagataaa atttcgcctt gtgccacatt taagaacgcc cacgcttcat caaggtctac
     3481 gattttgaag atagagcggt cgctgtggat aaaatctaag gcaaaggtac taatcacaat
     3541 cagcatggaa accgatagta attcaatggt cgtgtattcc tcaaaagtcg tgtccttatc
     3601 tggcagtaca aggtcggcta cttgaatgat attgagctga ttatctaaac tgatagcatt
     3661 ttccaccgtt ccgtctgaaa acagaagatg tgcaaaatca tagtctgtaa agctgtcgat
     3721 atggtctgcg atattgcgtg aaattgcggt atcttcacag cgtaactcgt ctatcacatg
     3781 aagcaagccc cttgtttcac tctgggtaac agaacgcacc gccttacgaa gtacggggaa
     3841 tttttcgccg tccctagagg aaataccagt taaaaaggtt agtatgtcga ttgccagact
     3901 ttcagcgtct ttcacattct tcataatcac aaacgggtca agaagccctg cgttgtcctt
     3961 gtcgcttgtt aggtttacga tattgatttc atgggcgatt tctggaagtg tttctttcca
     4021 gtttccacgc tctgattttg ggtctaagat aaccgcttga ccgccaaaca aaacagaata
     4081 gtacacaagc aggttattac agaatgactt cccaccgcca agcgaaccaa caaaagcaga
     4141 agcaagggca tttgtaactg taccttttac gccttgactg gcaagggacg gttgcagata
     4201 tacatttctt cccgtatcaa cggaatagcc catatagata cccgtgtttt cccctaactg
     4261 ctgtgtcgca ccaaaaccaa gcccagctaa gaagtctgat tttacatact gcacataatc
     4321 attgatatat cgcttgctgg ctggtagaaa ttcagaatga agccccagca tatccccagc
     4381 aggacgtact aacttcacat tcaaatcgtc ataaaaatct ttgacttcat cacaacggcg
     4441 tttcagttcg tccaaatcat cagcagacac acggataaca taagagagct tatacatact
     4501 ttcttttgtc tggtctaaat cggtttccag ctcgtccacg ctgtctaaag cgtctactac
     4561 atttgagctg gtttcacttc cagcttgata agcgtgatta tcaaggtctt tcagttcctt
     4621 tttcttgttg cggacggtcg ttaatgcttt tcggttttcc acgatttcta cattcatgct
     4681 cgtatcaacg ggaaaggtaa attgctgttg ctggaaatag aagatttcac tagacggaaa
     4741 atcaagctcg cctacaatcg cattgacggt aaaataggac acataacttt ccttgtcctc
     4801 atgttccaat cgtaaatatc gctggctttc ctcaatcaca caccttgtcg ggcggataag
     4861 gtcgtaatac ttgataagtg tttctttctt atactttttc tttggtagct ggtgctcata
     4921 atcttcatag gcgataccgt ccctgccgta aagatgttcc ataagatacc caaagtcatt
     4981 gatttccaga cggcgaacct taaagcgacg ggagatttta ttttccagta acttttccat
     5041 tttcatgtaa cggttgattt catcattcgg catggaaaca aagtcgttca tcagcgtgtg
     5101 gttcacttca tggagaaact ctttgaacgt cagccacgcc gattttttaa ggttcttcag
     5161 attgagctgt tcttccgtaa ccatgagttt aaagccaaga aaaaagcggt agtccacttg
     5221 attgtcccca atcattgata ctaacgcttc ggtctgttcg tctatcttct ggtaagcgac
     5281 ttcctttaat ttccccgtaa ccaatctttt tgactgctcc tgcatacttc ttatagagct
     5341 ttccgtggca atctgcaaag catgaatttt accctcacgg gactgtgcga ttagctgtcg
     5401 gaaactgtca tgcacgataa atttctgttc tgcggataag aaagaatagt tatacggtat
     5461 cagctcatag taggcgaaca cctcattgtc cttgttccag acaaggttgt tgtcaatata
     5521 tttaatcggg aacataactc acactcctta ctgccgtgat tgtttcgttg aatatttctt
     5581 tttgcagttt tacggctttt cctgcataag tgattttcgg tcgcaacgca taggttatct
     5641 gtgatttcaa aaagctgtat ggcttctttc cgtcaaaggt tttctgcgac ataaaccaag
     5701 tgaggaaagc aggaataccg aagtatttta aaaatgctcc ctcaatcatg gaaagtgggg
     5761 gcatatcccc aaacagaatg atgataaatt ctgtaatcac aaaccatgta atctgtgtaa
     5821 aggtaacggg aaagggcaag ttaaagtcat tgattgcata caagactttt tctacattcc
     5881 agatacccgt gtagcttcta atctttttca agttctttca actcctctca taagtttcta
     5941 aatggaaaag gacagccctg tttcagactg tcccttaaag agaaatacgc cgtcagtagc
     6001 aacaatgctt gtcgctgatc ttccagcgtt aatatggtat ctcgcacatt cctcggcttg
     6061 ttgcaatgaa gcaaccgccc atatccaaat ctcgcccgta tgcttcatag tcaatatagt
     6121 tctgcaagct agggggaata tcgccaagtg cctgcaattc atctatgtag taataggcaa
     6181 catctgtcat ggtttcacag tcgggataat agtaaatatc gtccttgtgt tccacgactt
     6241 cctccagcgt cccataatga ccaataaatt cgtccaaaca atccacgata tagtcgggaa
     6301 gttcctctat catttcatac atttcattga gttcatcaat ggaaacatac tccccaatct
     6361 caatcgggaa gttatcggta tcatggattg cgtattcttc atactgttca ttcaagccga
     6421 ttttttcttt cacatcttcc tcgtcaatag ggaaagtaaa ccaagcaccg actaaatagc
     6481 cctcattata cttgccaaga ttagcgatat aaactgccat atcatcaatc atacttactc
     6541 tggcaattca aagataccgt gttccgttac taaaaatttc ccgtgttcct gcaagtgtga
     6601 agcataggtt tcaaagtcaa aatagtattc ttgacagtcc tcggataaat gtttgaatgt
     6661 agggtcattc atcagctttt gccttgcaac atcaatcatg cttttacagt cgggataaag
     6721 cgtaattaca ttcctgcaaa tataaagtgc ttctaaattt tcatacaccg tatgaagcat
     6781 tgtatattct tcctgcatat cgcttgaaag ctggcgatac atataatcta attcattgag
     6841 ctggtacacg cttgtatgct catggacttc atcagcataa ggcaacaatt tttcaataat
     6901 gcggtaatct tgactttctg tactgacacc taacttttct tcaaactcgg caacctctat
     6961 cggcaggtcg aaccagtatg atgttgtttc ttcgccagtt gttcttttcg tttccaccag
     7021 tacccttgtt tcctgcattg ttcctcacgt cctttctgtt gtttcatcac atcttttaaa
     7081 gtctggcatg acataccaaa cacatatttt gaaaaatctt ctaactgttt ttcttcatag
     7141 tcggcaaggt tcagttgctt catttcatgc cacaccttac gcttgtaaga gggcaggtct
     7201 gaaatgtttt cacaaccaac ttttgcctgc atatctctaa aaatatcgtt cattacatca
     7261 ctccaatctg aaatttaggt aagaaaaaag cagtcaatcc taagactaac tgctttgtgt
     7321 gtatggatat gaagttgtca aactgggatt tatctggcag acttgtttat ccactcatca
     7381 agaaatttca tttgttcttc cgtgtgaaac caatgctctc cgtttctcat aacagtaagt
     7441 gttgcattag tttgttttgt aaattcagat atagttgcat aagaagtcaa gttatctttc
     7501 tcaccaaata aaatatttgt tggaattttc catgtagttg gattttcttt tacataacag
     7561 agatattccc atgagagtgt ttctccaaaa gttgttttaa tttctttttt atctcgaagt
     7621 tcatcttctg taacatttgc ccaatacatc atatctgcaa tcagtttttc catattcaca
     7681 ataggtgaaa taaaatatgc tttttctatt tgcttatctg ataaggcgtt catagcgaaa
     7741 taggcaccta tgctatttgc aactatttga acagatttgt aatgtttgca aatcaaatca
     7801 aaaagtgatg gaaattcttc ttttgcttcc catggatatt gtgcagtata gttgagtcca
     7861 accacatcac aatcactaaa aagaggtttg taatgtgaag actcctctgc atttccacct
     7921 ttaccatgta tataaataac tactttatcc ataatagttg tcctcctcaa cttcaaattt
     7981 gtcgctttct tcatatccac attatatcat tctcatatca gcaccacaat aaaattttac
     8041 gcaccgataa tcttattgaa cagctctaac agtacgtctt tcacaccgcc agcattgaat
     8101 accaatccaa cggcaacaag ggcaactacc aagaagccga taagtttaga aaactcacgt
     8161 ttgaacccta agtagatacc aataaccaca atcgccataa gcactaagct ctgggcgttg
     8221 cttaaaaacc atgtgtatat ggataggtaa gttcctgata ttataaatat ctcaaacttt
     8281 tccccccatt cacacggagc gtgcgacttt caacgcactc cgcgttccat cgtgtttata
     8341 ttgaaaagta tttatgtagt agacctatat caagtttaat tcttgattgc cagctaatac
     8401 tctatattta tttagtctta tgagctggac tttatttagc ttcaatagag ctatatattt
     8461 ttgtattgtt tcttctgttt tagcgtgtat tagacggtgt accgcctctt ttaccaaaat
     8521 atgattttta taatcgtcat ttccaccagc tccagttggt acaatatgat gacaatgtat
     8581 ttcattagct tgttgaaatt cttccagagt tatagcacat tttccatgtt gagcagaaaa
     8641 tagcgaaatt cgattgtctg cgtattctat tgtgcgattt tccaaagata atttcattaa
     8701 ctggtacatc agtaatttat caacacttag attggtgtgg ataaattttc ttccctctag
     8761 agtgtagcaa ttcgctaaat acacctttgc cattggtttt ctgtgttgga tatatccaac
     8821 agggaaaata ggttcgccct cgccagcaac ataccggagc attttagatt taccatatct
     8881 tgttgcctcc tttgtcgtaa gttgtctgcc tgtttttctc aatctgcccc ttttgtttgt
     8941 acctaatctg ttagtgaaga tagccattac agctctattc agtttcatac aatccagatt
     9001 tacattcgtt gcaatctgat aataattttg catacctaat accattgaat tataaagtct
     9061 tgtttcttct aattccgttt tcccttttga gggagaagca attttctttg cctgtgatac
     9121 cagcttgtct ttttggtttt tgaattgttt atcacttata tgtgatttaa caactaactt
     9181 ctttcttctc ggtatcattt taatcttgaa accaagaaag tcggagtatc tttttctaac
     9241 atttacaatt cttgtttttt cttgtgatac ttccaatttt aatcgttgtt caatccattg
     9301 agtgattgct attttggctt tttcagcact ttccttgtag cggcagaaaa ctctaaaatc
     9361 atctgcataa cgaaccatat acatttcctt taactttgtt ttcttcattt ctttgtaagc
     9421 gttgctttta catgggctac cgcttttatt gatatgaacc acatagtttt ttgtaacagg
     9481 attttcctgc cattggcttt ctacccaatg gtctaactca ttaagaacaa tgtttgctag
     9541 tagtggggat attattcccc cttgcggagt tcctttctct ggatatgtta ttgtaccgtt
     9601 agtcattttg attggagctt ttaatatcct ttttaaaatg aatatcaagt gcttgtcccg
     9661 tattcccata gcccatatct gttttatcag cttggaatgg ttcacgttgt caaagaaacc
     9721 cttaatatca aattcaatca cataatgtag ctggctgatt tgtaggcggt tataggttgc
     9781 ttttattgca ttttcaactg acctattagg tctgaaacca tagctgtttt cactaaattt
     9841 agcttcgcag attggttcta atacttgttt tatacattgt tgtataagcc tgtcccacat
     9901 acaaggaata cctagaggtc tggttttacc atttggtttt ggtatttctt ttcgcctcac
     9961 tggcttaggt cgatacccat gtggactgcc tgcaacaatg tatcttactt ttttgacaac
    10021 tgtttctgct ggcaatttgc caatatcttt aattattgta ccgtctgttc ctgctgtttt
    10081 actgcctgca tttgctttga tatttcgata tgccagtaat atattttctc tcgataggat
    10141 aatatccata agatgagtga aaatatctcc attcttactt ttggcatata aatcatcaaa
    10201 ggtgttttgc atttcgtaat attcagcgtg tcttaaatct tctacacaca atgtttcatt
    10261 tttattttta ggcataaggc ttcactcctt tgcttgaaat tgagtgagct tttttatctt
    10321 actcgtaatc cttattgaaa caacataata cttttctaat atatacacga cttgagggca
    10381 ttcctccatt ctcattacaa gaatttctta ggttcgccct ctgcttttca gcattagttc
    10441 aactgcttat tgttcttcgt cagtttattc tcttgatgag aacccaatac ctttcctcgt
    10501 tccgataatc ttatctatac atatatatcc ttaggtcact agctataagc ctgctggctt
    10561 gataccgcct gtaacgttat atggcatttc ataacctata ttcttacttt gccacaccag
    10621 ctacgatttc tcgtaccttt gcatttctac aaagttcaaa tttagacccg tacattcgct
    10681 gtttcgtcag ttccttatag aacattctaa ccatagatat tttatagacc cccgacctgt
    10741 tggatacgct acccgcctct ggatagtttt cgatagaaga tatatgttca tcaactatta
    10801 cggtatcttt cagccgtctt taccgagctt caaacattct gagtttcctc atacaatgct
    10861 tgtcggaggc tcagggcagg cgtttcagag cgttacttca tcattccacc tgtcagatta
    10921 tcagttctcc taataaccaa actttttcgt tcttttatta gtgccttagc ttttcactaa
    10981 ggaacgagtc gcacataaat tttgtccgaa attcatttaa ttgtcctctc tttctttgat
    11041 ttcttccata catctgtcag cttctttgcc gacagttaaa atgcacatca agactacacc
    11101 gatacccatt ccaaatgata ccagcaataa gtctttcaat aattcccaca ttttttcatc
    11161 actcctttac gttggcaacc atttcttcaa ccgtggctgt ctgttgcttg attatctggt
    11221 agtgtcgttc ggtcagtttt gcctgctttt caatcgtttc cagatactcc gtctgattgt
    11281 ccttgtctat ctgcttcaac atcttcaagg tcggtgcaac ctgcctttgt agccagttga
    11341 gtgtacgctc cagcgtgtaa ggttctggct gtgttgtcag ctttacgggc ggtcgcccct
    11401 cgccaatgaa ccaagcccag cgtacattgg ttttccagtc gctttttcgc ttgtctggtt
    11461 ctttatcagc gaagcggata tattgattga taatagaaaa tgctgtcagt tctgcgtcat
    11521 aatgtgtcag cagttccaca acagcataat aggcacgttc atttttcaaa cgtatctcaa
    11581 atctattttt tatggggact tcctcaatcg gtatgccaag tttggcgtac tgttcgtaat
    11641 tcttttcata acagcagaag tacacttcac ttgaaaatga accaatatac agcgtgtgtc
    11701 ccataccgta tttatccgtt tcattatgct ttaccagctc tccagaacca tagcttttga
    11761 aagaacggaa tttagaaata cattcctcat tctcgcattt tcgtatcagc tctggaatat
    11821 caagtaagcc cgttcggtca ttgattgcca aatcaagacg cttcattaca ccgccctcaa
    11881 ccaatgcgtc cgtgaagaag tcataccaac ttcgctcttg tgccagcaga tagctttcaa
    11941 actggcgaca gcctttgcct ttcagttcca gcaggacacc tttttcttcg tcctgcgata
    12001 catacacaaa cacatctccg atatggtaat gctcggtgta tttgtaatgt ccgtaatctt
    12061 cgtgaagcat atagccgatg ttgagcttca atatatcctt gatgatatgc tttatatcca
    12121 ttgtgggaaa acggatacgc acataatcaa acagcaggaa catgggattg ttgggattga
    12181 atttttccac cgcttctaaa agcgtatgtt tcatgtcctc ggtcagcgtt acctttcctg
    12241 cttcgatacg gctcaaatgt tcacggctga tatttgccat gattgcaagc cttgtctgcg
    12301 atacgccgta tgcacagcgt ttttctttca aggcggttaa aaaatcagtt tcattcagtt
    12361 gtcatacccc caatcgtgat aattttgtga tattgtgata atttcaaggc tttatcacaa
    12421 aaggcgaaat gtacgaaaaa cccttatttc atgcggtctt gcaaaggttt ttgtggaagt
    12481 ttccgccgta attgtgcccc tctgttagat aatgaggggc ttgtatctgc tggcgtggct
    12541 aacgccacac cagcaacggc tagtccgtgc cgtcgccttt cgcttcgcac gtcgccgtcc
    12601 cgtcctgcct tgcgtatgca agtgagccta tggtctgcaa aaaatcatgt ccttttggaa
    12661 ctaagggtgt gtaaaattca cttatgacgc ttgttcccac atcacaatag ccacgtccct
    12721 tgatacgctt ctggaaaaac tgttttttca catcagaact gaacagcata ccgtaaccta
    12781 attcgctgat acgccccaag ccaacacgga aattaaaatt atctctgata ccgtccgaga
    12841 aatattttgc gtctggacgc tggcaggcaa caataaggaa atatcctgct tgtcgtccta
    12901 acatgacgat tttctttagc tggctaagta ggctcacact ttcttttgtc cccagcattt
    12961 caaaaaacgc cacatattca tcaaagataa gaaagcaggg cggtaaacca agataggcat
    13021 agttttcgcc cgttttatag tctgggtgtc gcttcatttc ttcgcttctt tgtaccatgc
    13081 cctcataaaa ggcattgaca caatcaatca tttcttcttt ggtgtgatac acatttccca
    13141 ttaccgtacc taaatctgca aggtcagcgt tcttcgggtc taatatgtaa agaacagcgt
    13201 tcgtatgtaa cagagcttca ataagcgtca gcagaaaata cgttttaccg ccaccagtcc
    13261 caccagcaat cagagcgtga gggagtgcgt catattccca tacaagattt ttcatcagcc
    13321 taagacagcc gttttctgct ttcacttcat caatggtaat gcggttcgct atcatatcat
    13381 aaagcatggt gtattcgata taaccgtcat gtaacgtctt gtcggtcagc tcacaataca
    13441 agccactttc caatttatcc tctaaccgta agagctggtc ttgatatttt cctaatgtaa
    13501 tttcacagcg gatatgaagc agtccttttt ccatttgata ataaatcttt ggaaaccaga
    13561 tgattttttc ccttgatctg ctttgcaggt cagtaaaaaa accgctgtct tgtacggtgt
    13621 ctgcttcata ccacttgttt tccagtatca ttcgtgccag cttttgacgg tgcaggagct
    13681 tcttgaaact gtcataacag aagcggtaat acagaaaagc gaccaatgca caaacaccag
    13741 tcgctatcag tagggttatg aagttgtaag tggaaagcgt caaaccgttg tctaataagc
    13801 tgaaatgctc ccaatcggta cgcatgagct gtttcatatt cagtagcagg ataaccgcaa
    13861 tgaatacaaa cagaagcgtc cctatggaaa agtggtagac aaggttcttg tcgctggctc
    13921 tgatacggtg tcctttgttt aaaatcattt tcataaatca atcactcctt tctgggtacg
    13981 aaaaaagcag tcaatcctaa gactaactgc tttgtgtgta tggatatgaa gttgtcaaac
    14041 tgggatttat tgttcttaac ttttctgtcg ttataaagct gacttacgca cattaacctc
    14101 tgcacagacc agcccagcta tatgctccgc tgtttcattt gtcagtacaa agagcattcc
    14161 gtcattacgg cattttttat gtgtgtcgcc attcaaggca taaacaaaac cttttacaca
    14221 ggtatcacta caggcattag ggtcaatcag tctcttgcag tcacgagaag tagtcatttt
    14281 cttttgcata tcagcaggaa gcgaagcgat tatatcctca tactttccag cgttgtctcc
    14341 gtaaatccgt gcaaaaacac ctgtcttgcg aaacacccaa ttcattactg ttttcttctc
    14401 tagttggtat gaagcggtgt aaccgctttt tgcttccttt attacaaggt cacagccctg
    14461 ctcaataagt ttggtattaa gtttctcgac aaacgcttgg tgttctggcg cgattgccga
    14521 tagaaattct ttgaatgaac ctttttcttt tgccattatc tttttcctcc acaaatttca
    14581 atttatccgt ttcttcatac acatattata acagttgctt atatccgcta caatgaaaat
    14641 ctagtttgcc agcttatttc tttggttgcc cctgcggtgc atggttctgt ggattgccta
    14701 cttgaccgcc tttattcttc aagataatat cgtcagcctt gatataccag tccacattga
    14761 cacctcgata gctggcgttt gctaccgtat cggctacggg attgacaagc tctacctctg
    14821 cattatacgg atagtccttg acgggaatat cagcaggaat tgatacttgt atcatacgtt
    14881 cctgcacact acatttcaaa tcataggttc ttcgtgtgat ttcttcactt gttgaaccgt
    14941 cgtcattttc tgctcgcacc tcatgtctga gggcagagaa cttcaataca ccgaaagttt
    15001 tttccttgtc taatacaata ccgtttgcta atctcataat catttacccc cttacttgct
    15061 ttcctcggct ggcaacatat catcagccgt taagatatag tttgtgaacc ctcgtccttt
    15121 gaccgcttta ccgtctgcgg taatctttgg attgataagt tttactcgct gttctggttt
    15181 gaaatgcttt tcgcctgctt tcgctggaat ggttacgata atatcatcag ccctttgtac
    15241 gtcagagtac aagttgtagc ttcttgatac gggcgtaaag cgtccgttaa tgcgttgctg
    15301 ttcaatcttg ttttcgccag caaattccaa gtttccaaaa gtctgtgcca tgttcggcac
    15361 tacatatttt aattccatag tgttttacct cgtttctttc ttctttttta agtttgttga
    15421 ttgtgctttc ttattctggg aattagggaa ataccagtaa tcccccagat agtaaagggt
    15481 aaatcaatgc ttcgcaccct tgactatccg tgtgcttgca ggttgttggc agacaagcca
    15541 gaataagtaa acgtctgccg tttgacagct tcggcagaga gcgtgatttt tcttttctca
    15601 taccgttacc gccttatgat ttcttcattt tacggcgttt gtaaagatat gttccagcca
    15661 gtccaccagc agatgtaagc aacattacca gaaatgccat gacatttgtg ttgtcgcccg
    15721 ttttaggact gtctgttggt ctgctcggtt tttctggtgt tgttggcgtt tcgggtttct
    15781 ctgggacttc tggtttttcc ttaaaagtaa tcgtctgtcc ctcgtcctca atgtccttat
    15841 gctcagtaac ttttttcggc tcgtttggat tgcttaaatc atacaattct tcaaaagtta
    15901 caagctgttt gccgtcaaga gaagtagcgt caaaggtaaa ggtaacttcc actttcatag
    15961 tttcgctgtc agcgataaac gtataatcac tttccacacg ttttccattt ataagaagct
    16021 ctgcattttc ttctttcaac atctgccagc ccacaagttt atactttgta ccaacttcca
    16081 agccctctaa ggttacagta tcaatgattg ttacgtcttt tcctgcttca agctctttgt
    16141 taccgtcctt atcggtagca gttgtatgta ttttgatgat acgttctgta ataagtaccg
    16201 tctgcccgtc gtcctcaata tctttatgct ccgcaacttt catgggttcg tctggattgc
    16261 ttaagtcgta taattcctcg aatgttacca gatttttacc gccaagctcg gacgcattga
    16321 atgtataaga aatttccact ttcatttctt catcatcagc aacaaaggta taatcgcttt
    16381 ctacacgttt cccgtcaatg ataatctcgg cgttttcttc ctttaacatc tgccagcctt
    16441 ttaactgata cttagtgcct tttgtaagtc cgtctaattt gacagtatca acgattgtta
    16501 cctcttttcc tgcaaggatt gtcttttcgc cgtctttact ggttgctgtg gtatggatag
    16561 tgatttcctt ttcgtattca tcagtcaaag tccctaaatc aatcacaaga ttatttcttg
    16621 ataccacgat ttcaaatggt gggataagtt ccatgccttt gttgctgtca gagcgtaatt
    16681 cttcaataat gtaagtatcg taaggcaacg cacctttgct gtcgtctggt tcagaagttc
    16741 caaaccatac accgtcctcg cttgttttgc cagcgttggt attgtgcttg tgcgaagccc
    16801 attttgaaga agtggagaat tgcccattat cgtcagttac cacaacatga ctttcgcccg
    16861 ttgtcttgct tgtgatccta aagggaacat cagcaagacg cttgtgtgtg cctgcaccga
    16921 ttttcacgcc ctcaatatcc ccacgcttaa tctgattgta gatagagtgg gcttcgtctg
    16981 ttaagtccac gatttttccg ttttctgtga ttgtaaaatc aatcggcttc gcaccgtctg
    17041 tcaagtaacc gtttggagct tgtttctcaa cgatacggaa attcccgtaa ggcaaaaggt
    17101 cagcagaagt agaagcgata ccctcaatat ccgtatggat tgtttttaca acttcgtttt
    17161 tcttgtatat cttgccctca accaataccg cattatcatt taaggaaatg atgtcaaagg
    17221 cagtatcttt caaagtggca cttccttgtg gtttggtatc tttggtttct aaatctcgtt
    17281 tctgaatttt gacaccgcca cgaatgactt tatctgatac ggaaaactgg ttacttccag
    17341 ttaatacggc aaggtcgccg tcctcggtaa tctgcgtaag gtataaggct tttatctgtt
    17401 cttcactacc attcgcctgc atatatgcac cgtctagtaa gtagcccgtt ggcgatttcg
    17461 tttcttcgac cgttagtgta ccaagaggta aaaacgcttt tccgtcctgc atatagaagc
    17521 tatcgccaga taccttgtat gcgtctgcta attttgtgat gtaatgggtt gtcccgttac
    17581 tgtctgtttc agcggttgtc tttgtaaccc atgtacgagt agcttcggca ggaagattgt
    17641 ctttattgta gaagcctgca taatatttcc atgtaaactc cgccccctct aaagaagcgt
    17701 tcccttgtgg gttggctttc tgtgtttcca tgtcaatttt aaaaagctca atcaaagtat
    17761 cggtaacttt tggcgtatca gatactttca aagtcgctgt ctttccagct tcgactttta
    17821 aggaatacac cgtagtatca actttatacc ccaatggtgc agataattct ttgatatata
    17881 cggtagtagc tttgacttct gcaacctctg tatttccgct gtcgtcagtc gtaagggtag
    17941 caatctgttt ggtgcaatcc ttatcggaaa agacaccgta agtcgcacca gcgatagagt
    18001 aatttccgtt accgttagta atgctggtat tattggaagt cttttgaagt ttggcatttc
    18061 cgacatttaa cttcgcccag aattgcccta attcctgccc ctcgccagag tagatataac
    18121 cgccgcattc atagcgtcct ttgttttctt tcacaaaggc ttttgcacca gcaaacactt
    18181 catcttgtgt tgcctttggt atttcatcat aagaagctcg cacgttatca cattgccagc
    18241 ctaagtgaac actcaatctt tgccacacaa caagctgtct taaaaggtag gcgtgatttt
    18301 tgcttatccc attgtggttg tcggtgtatt gcttcacata ttcgatagat aaggcaacat
    18361 cacttatctg gtcggcactc atacgggagc ttgcgtcagc tctggtcttg tagccgttct
    18421 taaaatctgt gttaatatcg atacaataag cgtcctcgcc ctcaacggtc aaatgcccct
    18481 cgttaaaggt agaaccaatc gaaccgtcat tcattacttt ttcaacgata ccgacacgtt
    18541 cttcactttc cgtccagtat tgcttgcttt ctgcatggac aagtgtagtc ggtaaagcag
    18601 taacgacagt cgcaaaggca agtacgcccg tacacaatcg tttcaatatc tttttcataa
    18661 ttctaaatgc tcctttcatt ttgggtaata aaatagccgt ccataatgaa cggctggaaa
    18721 tagaaaagga acgtcaattt aggcgttcca tagtctatga aatattcaat ttttttcttg
    18781 cttcaatact gatgtgccgt accatatctt tgcatatcta ggaaaacttg cgtatcaagg
    18841 ctcattcatt ggtagtaaat tagtagtaaa ttgatgtgtt tgtttccttg aaaatgctga
    18901 tagatactat gttttagcgg ataatcaact ttttagtatg ttttttgcat aaaaattgag
    18961 tagatagtag ttttattgta cttaatgatt gtatttaagt gattagattt gaaattgaat
    19021 aatgtagata ataaaaaaat attaacagaa cttaataaac tccattaata tttttttatt
    19081 atttttgaaa ctgtgataat tatcacggaa gcatagaaaa taaagtgtta agatttaaac
    19141 aagatagtaa gtaagtaaaa ctaaaatata agaaaggtga taaaaatgaa actaaaatta
    19201 gattcatcta agttcaatga aggtctgaat tatctaaaaa aagactacaa gatatttgca
    19261 ccagttttaa taccatttaa aggtactttt tcagatactg atgttataag atacaaggag
    19321 gtaaacgctt ttgaagaaat ggaatttgct aagaaagcaa acttttcacc aaaagatgtt
    19381 gtacttccca taaatcaagt attgttttat tttactgaaa aagagtttaa ggaaagcgat
    19441 ttagacaaca agaaaatttt aattttctta agagcttgtg acataaatgg tataaaaaga
    19501 cttgatgaaa tatatctaaa taatggtgaa gaaaaagatt atttttataa aaatatcaga
    19561 gataaagtaa agtttgcact tgtagggtgt aaggaaagtt ttagaaactg tttttgtgtg
    19621 agcatggatt ctaacaaaac tgataattat tcaattggat taaatataga aggagataca
    19681 ctgtacttag atataaagga tagtgaattt gaagtattta atggagaagc aactgaattt
    19741 aatgttgatt atgtaactga taatttaata tctgtagatg tgccagagaa tattgattca
    19801 aatgaaatga taggaaattc aatatgggat gaatatgata caagatgtat aggatgtggt
    19861 agatgtaatt ttgtatgtcc aacatgttca tgttttacaa tgcaggatat tttctataag
    19921 gaaaacgaaa atgtaggtga gagaagaagg gtttgggctt cttgtcaagt agatggatat
    19981 acagatatag caggtggaaa ttcttttaga aaaaaacaag gcgaaagaat gagatttaaa
    20041 actatgcata aaatacatga ttttaaaaaa agattcggat atcatatgtg tgttggctgt
    20101 ggaagatgtg atgatgcctg tccgcaatac atatcatttt caaagtgtat agaaaaaata
    20161 aatgatttag taattagtaa ggaggaagta taaatgaacc catatatacc agtaagtgca
    20221 aaaatactag atatagttaa acatactgat aaagaatgga cttttagagt aaactgcaat
    20281 acaaaaggtg tattgcctgg aaagttttat gagatatcta tacctaaata cggtgaaagt
    20341 ccaatatcag tatcaggata tggagaggat tatattgact ttacaataag aaatgtagga
    20401 aaagtaacta gcgagttgtt taattataaa gaaggagatt ctttttttat aagaggtcct
    20461 tatggaaatg gatttgatgt atccctttat gaaggaagag aaattgtagt agtggcagga
    20521 ggaagtgcat tagcccctgt aagaggaata gttgaatatt tttataataa taaagaaaaa
    20581 tgcgaaaagt ttaaattaat agtaggattt aaatcaccaa aagatatttt atttgcagat
    20641 gatttaaaga gatggagtaa aaaacttgat attttagtta ctgtagatgg agcagaggaa
    20701 ggatatagtg gtaatgtagg attagtaaca aaatacatac cagaattgga tatgaaagat
    20761 ataaacaata cttctatagt tgtagttgga cctccaatga tgatgaaatt tacagtagaa
    20821 gaatttttaa aaagagattt agatgaaaag aacatttggg tttcttatga aagaaaaatg
    20881 tgttgtggaa taggtaaatg tggacattgt aaaatggatg atacttacat atgtttagat
    20941 ggaccagtat ttgattattc atatgctaaa aatcttattg attagggggt gaagtttgtg
    21001 ataagagatt taaataccaa aaaagtaatg aaaaatgctt atagaattac aaaaacaaaa
    21061 tatgagactt ctttaagagt tagagtacct ggaggtctta ttgaccctga gagtttagct
    21121 gtagtttcta aaattgcaag tgagtacggc aatggacagg tgcacataac tacaagacag
    21181 gggtttgaaa tattaggaat aaatatggaa gatatggaag aaataaataa aattatacaa
    21241 cctgttattg aaaaaatgaa tataaatcaa agtgagaaaa acgcgggtta tccagcagca
    21301 ggtacaagaa atatagcagc ttgtatagga aataaagtct gtccaaaggc tcaatataat
    21361 acaactgaat ttgctaaaag aatagaaaaa gctatatttc caaatgattt acattttaaa
    21421 gtggctttaa ctggttgtcc aaatgattgt ataaaagcta gaatgaatga ctttggaatt
    21481 attggtatgg ctttaccaat atatgaaaag gatagatgtg taaattgtgg agcatgtgta
    21541 aaaaaatgtt ctaagatatc tgttggagca ttaaaaacag aaaataataa ggtggtaaga
    21601 gataaagata agtgtatagg ctgtggagag tgtgtactaa attgcccaac aaatgcatgg
    21661 actagagatg agaaaaaata ctatagatta gctataatgg gtagaacagg aaagaaaaac
    21721 cctagactag cagaagattt tcttttatgg gtagatgagg acagcataat aaagataata
    21781 cttaatactt atagatatgt agaaaagtat atagataaag atgcaccagg aggaaaagaa
    21841 catataggat atataattga tagaacagga tttatggaat ttaaaaaatg ggcacttgaa
    21901 ggtgtagagc ttccagaaat aactaaaatg tacgaaaaca tatactggag tggaattaaa
    21961 tatctataaa ttgagtaaaa catatatttg aataaattaa aatttaatag aaggaagagg
    22021 gagttatgca taaagaaact ttggataaat taactaatgc agctataaat aagataaatt
    22081 tattaaacac aagtaaagta aaatatttgg tatcttctgc gtttgcagga ctttatgtag
    22141 gtataggtat acttttgata tttactattg gaggactttt gactgatgca ggttcaccta
    22201 tgactaagat agtaatgggg ttatcatttg caatagcact aagtttggtt ataatgacgg
    22261 gaacagagtt atttactgga aacaatatgg ttatgtctgc tggtatgtta aataaaggtg
    22321 taagtataaa agatacttct aaaatatggg catacagttg ggtaggtaat ttaatcggag
    22381 ctttggtttt aggcattata tttgtaggaa ctggtctagt agacaaagga cctgtagctg
    22441 aattttttgc aaatacagca gctagtaaag catccatgcc atttacagct cttttcttta
    22501 gagggatttt atgtaatatt ctagtatgtg tatcagtgtt gtgttcgttt agaactaata
    22561 gtgatactgc aaaaataatt atgatattct tatgtttatt tgcttttata acatcaggtt
    22621 ttgagcatag tgtagcaaat atgacaattt atagtgtttc attattttca ccaacaataa
    22681 gtacagttac tattggagga gctatttata atttagtagc tgtaacactt ggaaatattg
    22741 ttggaggagc tttatttatg ggtcttggaa cttatatatt aggtaaagaa aagcttaatt
    22801 aaatttattg tataaattat aactctcttg ataaatacat ttttagtatt gttgagagag
    22861 ttatttttat atttttgaaa aaatatttga aacaaaaaaa atatgggagc atacgaaaat
    22921 atatcggtta tatatataaa aaatacgttt atatatgaat tatatagttc taaatataaa
    22981 aaaagttaaa gtcctaccgt aaaaaagcgc attttgaata agataacaaa tatgataaaa
    23041 ttggtcttgt tgaaattttt aggggggata tgatgacaaa gaaactagta atatcaaaaa
    23101 caaagttgtt tatttttata atagcattta tttctatatt tatatattta tttggaagta
    23161 aaaatacact tataggtgta ggtatagtaa cagctatgct aacactcttg gaaagagatt
    23221 taactatttc tccaattaaa aatttactga agtatttagc aataaatata atcttaggaa
    23281 tactatcatt ttttgcagta caaaatatgt atttaggagt tttattaaat tttatagcat
    23341 tatttataat agggtatgta tttagttatg acttaaaaag agcagtatat gtaccctttg
    23401 gtctaatgta tatatttatg gtaagtatac ctgtaggaaa aagtgaattt cctatgagat
    23461 tgtcggcttt agctgttgga gcagttataa taatgattgc tcaatttgtt atgaatagaa
    23521 ataggatgaa aaatgtcgga gataaagaac tgatatctat atgtgatgaa ttattagaaa
    23581 aaattagcct tttaaaaaat actattaatg atgatagttc tataattaaa tctagtatga
    23641 gaaaaataga tagctgtaat tatagaataa attctatatc taaaaatttg aaaatggtta
    23701 tttttgataa tagaaaagat gacttttata tcagtattag aggtatagac ataatgaata
    23761 ttttattttc attagaaaga ataagtttaa tcctggaaag atacaaaaag gatagtaaag
    23821 aatttgaaga tgaagatata aaaaatattt tagaagaaag tagcataaat agtaaatcag
    23881 atgttttagt tgtagcaacg aaagaaataa actatattaa gatgtgttta gaaaataaag
    23941 ataccataac tgataaagag atattaggat ttagagatta tgttattgct caggatacta
    24001 aaaatataaa tttaaaagaa atttatagtg ttttagaaaa tttatatgag tttttagtag
    24061 attataaaaa agtaaaatca agagacgaaa agaaagctga aagaaaatca aagatacctc
    24121 atgaatttaa acgactatca atatataaga aaaactttaa tttaaattct ataagatttt
    24181 cttatgcagt aaagattgct ttagctacag ctgtagcggg ttttattatg gattatttcc
    24241 atttaagaga tggaagatgg ataatgttaa ctgtcttttc attaacacaa ccttacgcag
    24301 aaaattgtat acaaaggtct agaaaaagaa tagaaggtac atttatagga gctgtaatat
    24361 ttattgtatt attttcaata ataaaagata gtacattaag gtcgttaata gttcttttag
    24421 cagggtatat aaactcttat gtagttgatt atagaaaatt aatggtatgt gtaactgttt
    24481 cagctcttgg ttcagcagta gttatgggag acccaaatgt tttaacaata agcaggattt
    24541 catatgtagc attaggagca attattgcat taatagtaaa taagtttata ttaccatatg
    24601 atgctaaaac aggctatcaa catgttatag aaatgtataa aggaatagtt aaaaatataa
    24661 ttgatgaagt caataagtct atagaaaatg tagctgatgt ttactatata aaaaatttat
    24721 tattgatacc atcacttatt gaagatagac ttatgttgat aaatgctata tataaagata
    24781 aacatcaaga ggatttttta gaaaatcaga aattactaat aagtaatatg tataatctat
    24841 atataaatgt taataaaaat aaaataaaag atgaagatgt tgaaaaaata ttgagagata
    24901 ccaattatat ttcaaattac aatgtagata agtatgatga aggaagaagt gtaattttag
    24961 agagtattgt aaatactaaa agtctaggtg acaagataat atgtctaaac ttactgcaaa
    25021 ctctaaatgg tgtcaaagaa atgtatagaa taagtaatat aactaaagtt tcaataaaag
    25081 aagcagctta gatattaaat tatagaatag ccatatattt aaaataaagt atatggctat
    25141 ttgttttata aaatactaaa agaaaataat atataaaaaa caaaaaacat atatttatga
    25201 attttatatg aaaatagtta aaatattgat ttttttcatt ggttgaaaaa acaatttact
    25261 taggataaac tataatagta ttcaaatatt atgggggtta gatttatgag taaagatgta
    25321 aaggtaaagc gtaataagaa atatgataca tttagtataa ctatggaact tgagagacct
    25381 ttactttatg atgaggttga gaacaaagat gataaaaata ataatagaaa atttaacata
    25441 aagaataaga tatttaaggg aataggtata ctatttgtat tgattttgct tggctttttc
    25501 atatggataa ataaaacata tgaacctcaa aagctggcaa aagaagctct agtcagcaat
    25561 agtaaagttg aagtaactgt aaatgaaaac atttcattta caccaaaagg aagaaaagtt
    25621 tctaaaggtt taattttgta tccaggagct aaagtagaaa tagaatctta tgctccactt
    25681 gcaagaaaaa tagcagaaag tggatatgag gttgtaatcg taaagatgcc acttaatcta
    25741 gctatacttg gaactaataa ggcacagaaa gttatggatt cttacaacaa catagaacat
    25801 tgggtaatag gaggtcattc attaggagga gttgcagcat caaattttgc acgtgataat
    25861 aaattaattg aaggcgttgt atttttagct tcttatccaa tgggtgatga gttgaaagaa
    25921 ttaggaaaaa aagttatatc tatatggggg agcaaagatg gagtagtcaa ttttaaaagt
    25981 cttgtagaat caaaacaaaa acttcctgat gatacaactt atgttgagat tgaaggagga
    26041 aatcatgcac aatttggaga ttatggaaaa caaaagggag ataatgatgc tattataagt
    26101 caagaaaaac aacttaatat tactgccaat agtatcatta aatttttaaa gaatatatct
    26161 taaactaaaa tttaaaaaat ataattttat aagttattat ttaaagtaaa tattaataat
    26221 ataatagaat gaatatttta ttacaagggg gattttaata tggaatacga tatgccactt
    26281 tacagaccac caagtgaggc ttatagtctt ataatacaag tcacactagg atgttctcat
    26341 aacaaatgta cgttttgtag tatgtacaaa tctaaaaaat ttaaaataaa gccactagaa
    26401 gtaataaaaa atgaaattga tatatttaga agatattata agcatgtaga aagaatattc
    26461 ttagcagatg gagatgcatt gataatacca atggagaaat taagagatat tatcttatat
    26521 ataaaagaag tttttccaga gtgtgaaaga attactatgt acggctctcc taaatctata
    26581 gagaaaaaat ctgatgatga acttaaagaa ttaagaaaac ttggtgttaa aatgatttat
    26641 ctagggcttg aaagtggaag caatgaagta ttagaagata ttaagaaagg ttttagtagt
    26701 gaacaattaa taaaagttgg tagaaaagtt aaaaaaagtg ggattaaatt atcagccact
    26761 gtaatagcag gtcttggagg aactaaaaaa acacatcagc atgcagttga tacaggaaaa
    26821 atgttaggag caatttcacc agattatgtg ggtgtactta gtttaatggt agaacctaat
    26881 actgaacttt acgatttact taaggcagga gagtttacaa tactagagga taaggctgtg
    26941 ttacaagaaa ttaaagagat gataaagaat atagatgcta atgaaaaaat tgtatttaga
    27001 agtaatcatg catcaaatta tgctaattta aaaggtgtat tacctgatga taaacaacgt
    27061 ctaattgatg aaattgatta ctatctaagt aaccaaaagc taaaaagaga agaatataga
    27121 agactatagt ttttgatata tcaatctata ttgataggta aatactaaga ttatttagat
    27181 acaaaaaatc atgctacatt aatagttgct tactattgat gtagcatgat ttttttatta
    27241 aaaaacaaaa tggtatattc atatataata tatcaataat aatgaaaatg tgaactagtt
    27301 taatagaatt ttacctatta taataaaaac aggaatttaa ataataaaaa gtaaagtaac
    27361 tttttattaa gtaactttac tttttatttt atttaatgtt gtattaaatt tatatatatt
    27421 aaaataatat acaaattttg aaaaagctct tataaaatga ttattaaagt aaagtttaat
    27481 ataaataaat tataaaatat taaactaatt tatcaatatt tcctgattga atatgcttaa
    27541 tgtttgattg aattttttta tatggccaat cccaccattt aatttctaat aattttgaaa
    27601 ttgtatcatt attaaatctc ttttttataa tttttgcagg tactcctcca acaatagaat
    27661 acggtggaac gtcattagta actactgctc ttgttccaat aattgcacca tcaccaatat
    27721 ttacacctga cataattata gaatcataac ctatccacac atcatttcca attataatgt
    27781 tacccttatt gtcccaagcg tccgttatat ggttgatatc gagtttccat tcttcataaa
    27841 agatgggaaa agtatatgtg gattttgatt tcattgagtg atttccacta gtcattagaa
    27901 attttgcatt acatgctatt gagcaaaact taccaattat taatttatca ttgtttatag
    27961 ggtaatgata caatacattg tttttctcaa aatctcttgg gtcattataa aagtcattat
    28021 atattgtgta atctccaact tctatatttt cccttgttat tacattttta agatatacag
    28081 tttgataatc attacttctt ggatatacct tatttgaact tggaatagtc atatttaaat
    28141 ctctccttta atatatatta tgtttttgac tattccacta ctacaataca tctcttcaca
    28201 gaatcactcc ttgttaagaa tcttcataag ataatggcgt ccttttttag tgttaagtcg
    28261 gatattcttt cttagtccat tctttttagc gtataactga caaactgtca ttttcttacc
    28321 aatagtgtca atgctatcat caaggtcatt ttgtattgct ttttccttat cccttaatga
    28381 tatatcatca cgttttccct ttgggggttt atcagtaggt acaagtttcc aagagtaaac
    28441 aaattgtggt ttaccaaatg aatatacata cttatatgcg tatcttccat cttttctctg
    28501 gctctctcca gttcttaaaa ttctatcttt attatctcgt cttttttcag ttgacatgat
    28561 aagaagctcc tctcaataac cgaattgagc ttgatacgtc atatgaatat tataacatat
    28621 aaggctcaat ttcattagat aaagtcaagt gtatcaacga ttttctcaaa ttgttttctc
    28681 tttatttgaa tgcgattgct attcataatg acccagccag aatcaaggtt ttcatcagca
    28741 agtttacgta attttttctc tccaatacga aagtattttg acgcttcttc aatcgtcaag
    28801 gtatattttt cccaaatagg tacatcagta ttgttcatag aatgtatcac tcctttctat
    28861 gttcgtagtt cagaagtaga tagatggctt tggtaagctc cattggtatt ttaaccaatc
    28921 ccattcttat gggcagaacc gtgtcataca ggtgtatcat tatactgtgg tacaggttac
    28981 ggcaaaacaa ccgttccaaa ggttattcac aaatcactat atagtagctc tcttgattaa
    29041 ggtcatggcg tatagtattt gttggctatc tgtatcacaa acgtatctat ctactttatt
    29101 cagttgtcaa agaacagtcg gcattgattt gtctataaaa aatcacaata gcttatgggc
    29161 ttttatagac aaataattag tgattctcca tgtaccaaat agcttgatac atggagagag
    29221 ggcgagatta agacaaatta aatctcaaaa tagcagtgat tagttttgtt cctagcattc
    29281 gctttgtttc ttcttctaca tgaatatagg gatttccgta ttcatcaaat aaagttttct
    29341 gtgaaagacg aatgatatag tgttcaaaat gtttaagtat tccgtttatt gcatttacat
    29401 cgccatgtac agcaagtaaa ataattgtaa aaggtaatac ttctttagta ggtttcattt
    29461 caatgttcct ccatgagttc tttcaactct tttagtgcat ttgttttgtg ataatgtatg
    29521 gtattttctg ctaaatccat caatgttgct atgtcagcat ttgtcatgtt gagaaagaat
    29581 gaaagtagaa ttatatcttg ttttcttttt gtaagttttc cgattgcttg tgccattaat
    29641 acatcttcaa ttcgtatgtt gtagtcgtaa gaaaccatac agatgtagtt agaatcataa
    29701 tcatctaaaa tactcaattt acttaattct gcaagtgaca aagattcgag agataccaaa
    29761 taatcatttc tgcgtttatt ttcgtcataa atatctctag catagttacg caaaactgtt
    29821 ttacagaaac tgtcgaattg atgttcaatt gtcttttcat caaccataag atttcaccct
    29881 ctttccatcg caaggagtta aataaccttg cttactccta tcacggtggg agggcgttaa
    29941 atcttcgata aatttcaaaa aaaagagaaa aaaatacaca ctctgcctat agggcaaaaa
    30001 tgtgtattct ttaaaacgta tttaatttat attggttgta agccaccacc atattgatgt
    30061 atggaaatat gcattggcta gcttttcata aaaatacaaa gatgcataag aaattaatag
    30121 aggggaaaaa cttattctgt tattaaaaag taggttaatt ctaataaatg ctattgcggt
    30181 cgaattaaac tatatacatg gcaatcaatc atgtttctat tctttattat gaattgtgac
    30241 agtattcttc aatcttaaaa ccacattttt ccaatacttt acttgaccct ctattgtagg
    30301 aatatacatt agcatgaatt ttgttaaggt tgtatttttc aaaggcaatt ttgcatattt
    30361 cttttactgc atttgttgct atccctttgc cccaatagtt cctagcaagc cagtaaccta
    30421 attcagcatt tttattaata gaggtatctt cttcaaatgt taggctgata cttccaatag
    30481 ccctttcttg ataaaaaata gcatagctaa gttgtttaac atctggagtt gccaaacaaa
    30541 aactaacaaa atctctagcg ttttgctccc tataagggtg ggggaagttg tcacgaagat
    30601 tctttgcaat ttctttatca ttcgcaaact caactaaatc ggtaatataa gcataattcc
    30661 actctataag ttccattttt cttctccttt tatgaaacag ctacaagaaa tctttctaag
    30721 ccaataccac ttatcaaaca gcgttctttt ttatttccaa gcatttgata agtccagtca
    30781 acaaatccac cgtcaactat ttcaacggtt tcatttcctt gtttgaccga taatttgaaa
    30841 ttgatacctt tataataatt attatcaaca tcatcattat gaattgataa ctctatatta
    30901 ggaaaaataa gtttgatagt ttcaaccatt ctgtcgaaaa atccgtcatt atctttgtat
    30961 ccgtttcttt tgcgtagaat aatagagaaa cgaacatttt ctatttcact taatatatct
    31021 ttataatagt ttaagtgctt ttctaacaac attttttcac aagtgtaaga ccctgtatct
    31081 ataccagatg aaaccataca atataagcca aaatgtgaat ataaaccttt acctacaaaa
    31141 ttttgtgctc ttattaccct agcagtagta gccatgtgga taggtatggt attattttct
    31201 tcttttcttt ttaatttatc agcaataatt attgccaaca tatttgaggg gtctgcaagt
    31261 gtttctgtcc ctcgtagagc acttactaca ttatattgat ctacggagcc aaaaacgcta
    31321 cagctaccta atggagcaga gggagaaagc ataatcgtct tgatatccat attgaatgct
    31381 tttctcaata attttgactc caaagcatga atttcttctg gatctatacc gctagggata
    31441 gtaaatctat ttagttggta tgactttaga atatcagttg cagttaaagt atttgcttgt
    31501 ctatcaaaca cttctaatag aagtgagttc aaatctgatt ttgatagagc tgataactta
    31561 tcaactatat tcttatcccc aattttattt gtaattctac ttaaaatatc actcatagtt
    31621 atcctccata ctgttacttt caaaataatt atagaatggt tacaacaact aatctaggtc
    31681 atttgaccaa aaatgaaaaa acactgaata tttactattc aatatttttt tactttgggt
    31741 ttatttgatt aaatcttgaa aatactgtaa tgcaaccctt tcagcttcaa cctttcggac
    31801 aataggactt tgtgataatt cctctcttaa ctcaagatac aggttgatag tagcctgcaa
    31861 tgcattaaca cagcttttat attcatggtt agcaaccgtc ttttctaatg cttcaatata
    31921 ttggggtgcg tccaattcaa tttttctaac tccacgaggt aatttaccta agagaagctg
    31981 tattaatggg gcaagtactg attgtcttaa aaaagataaa aaatcaattg tttcaaatag
    32041 ttctctacgt ccaatcttag tgcaagcgta atgaacccaa atccaaaatc tatcttcaat
    32101 ccactgtaag tctggagttg ggaagtatgc ttctttttta gtataacacc tctcactttc
    32161 ttttattagc tatcaatcca acataattat gcataggagt attatataat gaaaaaataa
    32221 aaaaaaatag gtcacttgac ccgaaataaa aaagcattga ataattatta ttcaatactt
    32281 ttttgaaatt atacttatgt tgtaggaaga ttctttaata cctctcgctg attaattaca
    32341 ctaaatcttt tgttttcata agcaattaga tgttcttgta cacattcatt tatagcacga
    32401 ttaatgcttc taattggagc gtttacttcg ctagcaagct gttttttggt aagcagattt
    32461 aattcacttc tataatagtg taaggatata cacctcagaa gtcgttcttt aacacttaaa
    32521 gatgataatt cttcaattaa ttcagcattt acaactaatt tactagatat ttctcgaatc
    32581 agaaattttg tagcttcaaa atctcccctt aaccagttta aaaaatcatc tctatgaagt
    32641 ttatatacat tacaatctgt gaaagcgaca atttcaacgg gttttttccc atcattaaat
    32701 tgttccattt ctccaaaaaa actaccactt ctataaagat gaatagttga gatgtttcct
    32761 ttcacattta agatgaatgc ttctgcaata ccgtcaatca taagaattac atattcattt
    32821 tcttgctcag caaaaagaat agtctctttc tttttatacg tttttttaac aagcttcttt
    32881 ttaatatctt cattcataaa atcaattaaa tgcatattca tccctcctta ccaaatcttt
    32941 gattaaatta tatcatcttt caattagtta ggtaagatag taaaaatata tttacataga
    33001 aactattcca ttattatttt ccagttgtca tttttctgca aagtaagctc aaactgagaa
    33061 agctgttgac aatagaacta gtaggaatat atgagcgaac catttcagta ttcaactgtt
    33121 gtaggttttc agtcagataa ttcttcaaac gttcaattcg tttgtcctgt gaatcttgcg
    33181 atgctctaac cagtttcata gatagcgttt taccttgtgc cacctgcaaa aaagaccatg
    33241 cttcgtcaag gtcaactatc ttgaagctag agcggtcagt atgaataaag tctaatgcaa
    33301 aggtactaat aacaatcaac atagcaacac taagaagttc tattgttgta tattcttcaa
    33361 agctagtgtt ggcatctggc aatacgaggt cagcaacttg aataatattc agctgtttct
    33421 ccaagctgat agactgcttc acatttccgt caccaaacag tagatgtgca aaatcatagt
    33481 ctacaaaact ttcgatatgg tcggctatgc tgttactgat agaagtatct tcttttcgta
    33541 attcatcaat gacaagtaat aaccctcgct gttcactttg ggttacattg cggattgctt
    33601 ttctaagcac tgggaactta tcactgtcac gactggagat accagcaagg aatgttagga
    33661 tatcaatcgc taaactttca gaatcatttt tacggctcaa aatgacgtaa gggtcaagca
    33721 atcctttgtt ttcatcatta ctggttaaat tgacaatgtt tatctcatgg gctatttctg
    33781 gtagcgtttc tttccatttg ccgcgttctg ctttagggtc aactatgacc gcctgtccgc
    33841 cgaatagtac cgcatagtaa acaagcatat tgttactgaa taatttacca ccacccaatg
    33901 aaccgataaa cgcagacgct aacacattgg taatagaacc ctttacccat tgactagcaa
    33961 gggcaggttt tagatagaca ttctttccag tgtccagatt gtagccaaga tagatatcct
    34021 catgttcgcc aagggtttgt gtcgctccaa aaccaagtcc agccaaaaaa tccgaagtga
    34081 catattgaat ataatcattg atgtaacgtt tgctgacagg aataaattcg ccatgcaatc
    34141 ccaacatatc cccaaaggga cgcacgagct tgagtgataa gtcgtcgtaa aagtctttga
    34201 cttcatcaca acgccttttt agctcgtcaa gatcctttgt agatacacgg acaacatagc
    34261 taagtttata catagattct ttacagttaa aagtctgttt ttaaaaaaat gtataaatta
    34321 taaatcaaaa tatagatact atcaatgacc cactaggtgc aaaaagcatt gatatggtta
    34381 aattatcaga cgctaaaagc tgggctatcc gaatgagtga agatgggtgt gcttataaat
    34441 ccattgacaa ttataagcgc tcactgaaag cgtcgttttt catggcaatt caagacgact
    34501 gtattagaaa gaatccattt aattttcagt taagtgatgt tttggaagat acaacagaac
    34561 caaaaatcgc tctaacacca gaacaggaaa tgggcttatt atcctttatg gagagcgata
    34621 agacttattg taaatattat gatgatgttg ttatcctctt agaaacagga ctacgcattt
    34681 ctgaattatg cggtttgact ttagaattgg atatgaaaaa taaagccatt atggtagacc
    34741 atcaattgtt gagtgatact aagattggct attatgtaga agttccaaag accacacagg
    34801 gtaagcgaga aattccaatg actgaaagag cttatcaatc atttgaacgt atcgtggaac
    34861 ggcgtaagaa cgctaaagca gaaccaatca ttgttgatgg ttaccagaac ttcctatttc
    34921 ttaaacaaga tggattacca aaacaagcaa ctcattatca aagcatgtta agagcgttag
    34981 tcaagaagta taataagacc catgaggaca agctaccaaa gattacgcca cataccttta
    35041 ggcatacact ctgtacaaat atggctaaca aaggaatgag tcctaatata ttgcaatata
    35101 ttatggggca taaaaacatt actatgacgc ttggctatta tgcacatggt tcatttagtt
    35161 cttcgagagc tgaaatggaa cggttataat cctagtagta tgactagagt ttactactta
    35221 tttactactt ttgatggcat tcttatacgg ttaaatgcca acttatgcaa agtatcttcc
    35281 aaaaagaaaa tgccgatact ccttgtagat acaggatata tcgacattta ccaacttatg
    35341 aaaagataat caaatttaat ataagttttt caaataaaaa gataccaaat tctttttcga
    35401 gaatctatat aacattactt aagcttggtt ggggtataaa caattgagta gctacttttg
    35461 tatggtgttc aactttagtc aaaactctta agtaatgcaa atgatttaga ttcattaata
    35521 ttcaatctct tcataagtag tgaaattcga gttatttctg cataattata ctatgattta
    35581 tagattaatt ctattagcat ccagaataat attgtttata tgagtaaaat ttaaagaata
    35641 ttgtgaaaat tataggatgt taaaataaat ttaggtaaaa aagaagtgtt tgtatattat
    35701 agagtacctt ttctaaaata tgtgggattg ttttaagaat tagaataaaa attattttta
    35761 aattagtatt tttataatgt atagtatttt taatgtataa ttaaattgtg cagaaaatag
    35821 aatttaaagt cctatagaat ttctgattat ggaggagaat atgaaaagaa aagttcaagt
    35881 aaaaaatatt actattggag aaggtagacc taaaatttgt gtaccaatta ttgggaaaaa
    35941 taaaaaagat attataaaag aggctaaaga gttaaaagat gcatgtttgg atattataga
    36001 gtggcgagtt gatttttttg agaatgtaga aaatattaaa gaagttaagg aagttctcta
    36061 tgaattaaga agttatatac atgatatccc tttattattc acatttagaa gtgtagtaga
    36121 agggggagaa aaattaatat caagagatta ttatactact ttgaataaag aaatttctaa
    36181 tacaggttta gtagatttaa tagatgtaga gttatttatg ggagatgagg tcatagatga
    36241 agtagttaat tttgctcata aaaaagaagt gaaagtaatt atatctaatc atgattttaa
    36301 taaaactcca aaaaaagaag agattgtatc tcgtttatgt agaatgcagg aattgggcgc
    36361 agatttaccc aaaatagctg ttatgccgca aaatgaaaaa gatgtgttag tgctacttga
    36421 agctacaaat gaaatgttta aaatttatgc agatagacca ataataacaa tgtcaatgtc
    36481 aggaatgggt gttataagta gattgtgtgg tgaaatattt ggttctgcat tgacttttgg
    36541 agctgcaaaa agtgtttcag caccagggca aatatcattt aaagagttaa attcagtact
    36601 taatctatta cataagagta ttaattaaat taattatata gaaatattag acggtatttt
    36661 tgaagatata aattaaatat aaaaaacttt tcagatagta aaatttaaat tgggcaatta
    36721 tatctgaaaa gcaactattt agtgtgtatt ttgaaagtga tatagaaaat cttataaatc
    36781 aactatggca tatttaaaat atgccattaa aacctactag acattagatt atagatggta
    36841 tactagcatt tctattattt atagatagta agttttcata ataactgttt tatctaaagt
    36901 agaagatata tttgtattat gtatatttgt cattattttt ttgtaattat gtatattaat
    36961 ggttatatat gtaatataat attatcactc tattttttgt atattgtaca ttacaacatt
    37021 tatatctatc atcatcaatt acagtagaat gtatgggata cttattttca cttaaccaat
    37081 atttttgcat attctttgtc caagactttg gaaacttcaa tactttcttg tttattataa
    37141 catcctcatc ttcaaaaata ttaacttctc tttctatttt tatttttctg ttgtatatct
    37201 tattgataga ttctttgtcg agttttatgt ctctatacat atcagggcaa tagcaacaaa
    37261 cataatttct tttttttcga cgtttaaatt tcacaacttt ctctatgcta atttctaatt
    37321 tttttgtacc atcttttata aatttaatat cttctatgtt ctcgcttgaa aaaatttctg
    37381 tcaatcttaa agtatctaca gtttctctaa ttatttgctt tttataagaa gagaatccat
    37441 atccaaaaga aaggtttaat ttattaggga tgtagccatt tttatattta aacatcttaa
    37501 ttttttccaa ttcagcatta tctttaaatt tcaacttttc atacctaaaa gttactttgc
    37561 taaaaagagt atattctaca tcaatatatt cttttgcaat cttaaattta tcgctacctt
    37621 caatcacaat catagcctat ctccaatcgt tttatattaa aataaggcca tagaacatgg
    37681 tctaatagta ctcattagca ctataagaca atgttaacac aaaaagacaa aaaaaggtta
    37741 tttatttcaa ataacctttt tttttatata aaatataaag aattatattt tattcttttt
    37801 tatgatgtct ataatctgtg atatcagatt tagttctctt gaatttaagt cttttaactc
    37861 ttcatttata tcattttcta aatatgtttt tccagtggaa gtaatatctt ttataagaac
    37921 atctgcagaa atatttaata tatttacaaa ttttatgaat gttttaagac ttggattctt
    37981 tttaccactt tcgatttgag ttatatacca aggcgatact ccaaccatat ttgcaaattc
    38041 ttttgaagtt aaatttgctt ttttccgttc ttctttaagt cttttaccta tataattcat
    38101 tattgttact atttccctca cttatatttc tttgtattta atgatgcact ttattaactc
    38161 tagcattgca atttgttctt tttcagttaa tttattaatc atttcataac attctaaagg
    38221 tacagagtta tcaacgcctt ctgttgtaat aatatttgca aataacaatt caagtggtat
    38281 gtctaaagca gtagcaattt tcattataat attgatagat gtatttgtct cagctctttc
    38341 aatctgacca atatatgttg gatgtaaacc tgccttttct gctagaaact cttgactata
    38401 tcccaatttt gttctataga cttttattct atctcctatt atttttccta tatttgccaa
    38461 ttattatccc tccactttag attatattca tagtttaagt tgttttatat agactattta
    38521 tactttttta gtctaaatat agactatata tgtttttata ctgaaataag tgctatttat
    38581 ttttttatag
//
LOCUS       DAEPHU010000037        38423 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 01A10CD0081
            SAMN05941466-rid12468953.denovo.037, whole genome shotgun sequence.
ACCESSION   DAEPHU010000037 DAEPHU010000000
VERSION     DAEPHU010000037.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941466
            Sequence Read Archive: SRR6291087
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 38423)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 38423)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068158.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 22:43:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,892
            CDSs (total)                      :: 3,805
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 87
            rRNAs                             :: 8, 1, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 55
            CDSs (without protein)            :: 55
            Pseudo Genes (ambiguous residues) :: 0 of 55
            Pseudo Genes (frameshifted)       :: 21 of 55
            Pseudo Genes (incomplete)         :: 28 of 55
            Pseudo Genes (internal stop)      :: 16 of 55
            Pseudo Genes (multiple problems)  :: 8 of 55
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..38423
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941466-rid12468953.denovo.037"
                     /strain="01A10CD0081"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            280..735
                     /gene="smpB"
                     /locus_tag="KR231_001974"
     CDS             280..735
                     /gene="smpB"
                     /locus_tag="KR231_001974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SsrA-binding protein SmpB"
                     /protein_id="HBH0004349.1"
                     /translation="MAGKKILATNKRARHEYFIEETYECGIELKGTEVKSIRQGKVNL
                     SDGFASVDNSEVFLKQVHISPYEQGNIFNVDSLRVRKLLLHKHEIRKLIGATTIKGYS
                     LIPLSLYLKNGKVKVEIALAKGKKLYDKRQDMAKKDAQRRIEREMTGKY"
     gene            893..1242
                     /gene="ssrA"
                     /locus_tag="KR231_001975"
     tmRNA           893..1242
                     /gene="ssrA"
                     /locus_tag="KR231_001975"
                     /product="transfer-messenger RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00023"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00023"
     gene            1357..3384
                     /locus_tag="KR231_001976"
     CDS             1357..3384
                     /locus_tag="KR231_001976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAM-dependent DNA methyltransferase"
                     /protein_id="HBH0004350.1"
                     /translation="MSIDNNFNHVAFLWNIAESLRGTYKEEDYRKVMLPLIVIRRFDC
                     LLDDYDREIIKSVYEEYDFLPEEERDELVIVDLKENHDINLQFYNVSDFTWKKLLDDS
                     ENIKSNFEEYLNGFSNNVKEIIGKFKFKDEINQLDKKDKLYAVLSKMYEVDLHINSVS
                     NNKMGYIYEEMLRRFTENSAAGEQYTPREVIRLCMEILFMGKENFLTEEGKVISIADF
                     CCGTGGMLSIAEDYVEKINPSAIVNVYGQELLDESFAICQADMLMKGQNPDNIRLGNT
                     LTQDRFNGEKIRFLISNPPFGVTWKDEEKKVKEEADLGFDGRFGAGTPRVSDGSLLFL
                     QNMISKMYDDEEGSRIAIIFNGSPLFTGDAGSGESNIRKWIIENDLLEGIIALPTDMF
                     YNTGIATYIWVLTNKKEAKRKGKIQLVNASEYYQLMRKSLGNKRKEISLEQIEQIKEI
                     YEKFEESENSKIFDNEDFGYRKVTIERPLKLSFKVNEEAIENVKNTTQFINLAVSKKK
                     DIEVKEKEEAEGKIKQDKLIKLLESFDNTLEYMDRDKFIKDLKAKSKEFDIQLSAGLI
                     KAIVNTIGVRNEDAEVCKDSKGNIESDSSLKDTESIGLKDDVYEYFEKEVKPHVNDAY
                     IDESSINNIGYEIPFTRHFYKYEELRSFAEIMKEVESLESEIALKIRKVLG"
     gene            3384..4775
                     /locus_tag="KR231_001977"
     CDS             3384..4775
                     /locus_tag="KR231_001977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010233411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HBH0004351.1"
                     /translation="MGYRYRSDDELKDSGVEWLGKIPKDWEVRQLKRVLSDRKENNEP
                     IKTSNILSLTIEKGVIPYSEKGTGGNKAKEDLTQYKLVYPNDIVLNSMNVIVGAVGLS
                     KYFGCASPAYYMLYKINANDDIRFYNYIFKSKLFQDSLKGLGNGIMMKQSETSGKLNT
                     IRMRIPMEKLSSVKIPIAFNLDQEKIANFLDEKTSQFDSIISKKEKLIERLEEAKKSL
                     ISEVVTGKVKVVKTDDGYELIKRSSEEMKDSGVEWLGEIPKEWDIKRLRFLGKLQNGI
                     SKSSDSFGYGYPFVSYSNVYRNIELPHIVEGLVNSTEEERKIYSVEEGDVFFTRTSET
                     VEEIGFASTCMKTIDNSTFAGFLIRFRPNDKRLYKGFSKYYFRCDLNRKYFVKEMNLV
                     TRASLSQNLLNNLSVVLPKYEEQVEIYNALELKVSYINLSINKLKYQIEKLKEAKQSL
                     ISEAVTGKIEILD"
     gene            4837..6108
                     /locus_tag="KR231_001978"
     CDS             4837..6108
                     /locus_tag="KR231_001978"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0004352.1"
                     /translation="MDKNIFQININTDVLIRLRNQINEEYYISYRKEFYDKNNKKHRA
                     WDKICAIMDRLDDTVDYLNKLKLNTGKYRRSAFDFFEFMNQASVVMDCITHLAKIFEV
                     PYEEVETSTEIFNELGKEGKGTDKKYFEYLRSLCSVHPMETSRHKIYQENSFECSPYV
                     VWNDKSIWTNDASDLYAVVYTSKDNDSFKRIHIYMNQIFEYVKRRVNFIENIIEHIEK
                     YQQEIIEIFRNTPIKKEEDFESYIDYLRNLKKEIEIRYGNDSFHELNYLIELFDLPLS
                     NPDNEEKMNLYKNALKYAIKFEHNSIQNMTNEGYKNNGILYPQVNITTTLLEELISLN
                     SGSEERRKYRYAIEKTSYLSYDSCWSDREWAYDQIDDMMPFLERYVTFDKAQSDFEHY
                     VLVKLALYLECLENECLINKNVPNDKKFRIK"
     gene            6143..9124
                     /locus_tag="KR231_001979"
     CDS             6143..9124
                     /locus_tag="KR231_001979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I restriction endonuclease subunit R"
                     /protein_id="HBH0004353.1"
                     /translation="MLPKEKHLEESIENHLVSIGYEQGHSQEFDLENCLFVDDLFRFL
                     ENTQKELLDEFKYNRGSNYKKAFIDLLNSNIKRRGLISVLRNGVEDIMMNGKFQLFYN
                     KPNLTTNKTAYENYKQNIFKITRQLKYSSKHNNTLDIVLSLNGFPVIVMELKNQFTNQ
                     NVYNAIKQFKKDRNPKETLFGFNQRVLVYFAVDTDEVYMTTELKGDKTFFLPFNKGNN
                     RGKGNPVVEGKEKTSYLWEEILTKDSLLDIIKRFYFIQEDDKGNQRAIFPRFHQLDAV
                     RKIVEDLKINKVGKNYLIQHSAGSGKTNTIAWTSHRLSSLHDEENNAIFDSIIVVTDR
                     KVLDKQLQNAIYQLEHKNGLVVKIDEDKNSSDLADAIVNRAKIIITTIQKFQYALPKI
                     EQLDKRRYAVIIDEAHSSTSGENMNALKETLAGKTLEEAKVIDAENEKNEKSSIDKMN
                     ELIEKRTNLGNISFFAFTATPKNKTMQVFGRIGEDGLPHEFHLYSMKQAIEEGFILDV
                     LKNFMPISVYYKVGKKIIDNPEFDKGEAKRAINKFVSLNEHNIRQKVETIVDDFVDNR
                     SMWLEGKAKGMIVTASRLHAVRYKLAIDQYIKEKGYDMKALVAFSGTVKDGDDEYTEV
                     GMNKEVAPDITDSNLPNIFDKNEFKLLIVAEKYQTGFDQPKLCAMYVDKKLDGVKTVQ
                     TLSRLNRTYPNKQTFILDFQNSVEDIQDAYKPYFEMTNIDKVTDPNVVNDLWYQLHEY
                     AVYTDEEVNDFTVLFYKEKRTSSQDAKMNNLIDKAVERYCYLEEDDEKKSDEFKKKCQ
                     KYITFYNFLIQIYPIKNLNLLRLQVYLVALLKKLPKKSKQRIDLDDMLSLDYYKLQKL
                     GLDDKKGTDISLYNGEGELVGISETATSRVSEADEEYLEDIIKKINDVFGVGLTEDDR
                     IMINTYEEMFKNDKDIMDIAKANSYEDLVSTFGKKYFKRGIVKTKNRNDRLVKEILTN
                     NNLQNYMIHYLAEKIYEEANR"
     gene            complement(9183..9353)
                     /locus_tag="KR231_001980"
     CDS             complement(9183..9353)
                     /locus_tag="KR231_001980"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0004354.1"
                     /translation="MNNDKPFIEFEEEVDFILTECKKEGVSIDRDTIELILDLDLKFL
                     ELKGIATPLEDE"
     gene            9634..9969
                     /locus_tag="KR231_001981"
     CDS             9634..9969
                     /locus_tag="KR231_001981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0004355.1"
                     /translation="MIKLWKKEDLNLLLEYPKEVVENVDNVINILDENYGCNRKLTDD
                     GGYVCIIEDIKEVENLKSNILKGLVEEFSDVIYEDEVNTYNSTLYLLSSDYSVTVISK
                     NEETEYLLK"
     gene            10033..10491
                     /locus_tag="KR231_001982"
                     /pseudo
     CDS             10033..10491
                     /locus_tag="KR231_001982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427593.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="JAB domain-containing protein"
     gene            10631..10924
                     /locus_tag="KR231_001983"
     CDS             10631..10924
                     /locus_tag="KR231_001983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0004356.1"
                     /translation="MFKKENRYMTKEIAENLPIEIAILLWNLIDDLTTEKDYLQLFEI
                     NPIGLGVVEIVHKQEVPEYEARIYIQNDKIKDKLKIYVIDNVEYRTMMFSNEY"
     gene            10951..11547
                     /locus_tag="KR231_001984"
     CDS             10951..11547
                     /locus_tag="KR231_001984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903546.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0004357.1"
                     /translation="MINNKSEIINKLFFNELKELIDKYNNIDDKTVDVIEKIFTCIED
                     EEIKNYLIRDNCKLQELVNTYNKLEDLNIDEAIFFAWYNLTINTISIDKASEYYDDLT
                     TSNYIEVENHIIYTNERDLRKYAEDELETMLSMEHHIDRLLHKDMLIDMWLNNTSKEE
                     VIEEILMSDDIEDILNLSPEYAFTLANGIEYRYSEKEE"
     gene            11700..11969
                     /locus_tag="KR231_001985"
     CDS             11700..11969
                     /locus_tag="KR231_001985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003487728.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mor transcription activator family protein"
                     /protein_id="HBH0004358.1"
                     /translation="MTNNNNNCDYKGIYADMVEVLGEEIVIKLHKYYRGQQITFPMKL
                     YSIEYVERYIVKNYRTKTIKEMCRELGYTEGWIKQLINKNRLNSK"
     gene            11995..12237
                     /locus_tag="KR231_001986"
     CDS             11995..12237
                     /locus_tag="KR231_001986"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0004359.1"
                     /translation="MILTVLAILMGTGIFFLINSMLDITYFGCGPIGFLWFGCFIVSY
                     AILTSLGGIVLGLLKWIVIGLIILFVIGLIANKIND"
     gene            12443..13576
                     /locus_tag="KR231_001987"
     CDS             12443..13576
                     /locus_tag="KR231_001987"
                     /inference="COORDINATES: protein
                     motif:HMM:NF012938.1,HMM:NF016983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosome-binding GTPase"
                     /protein_id="HBH0004360.1"
                     /translation="MQDFDFISETIKKFQSDLENMDKVNILVVGKTGVGKSTLINNIF
                     REELAETGIGRPVTQHLKKISKEGLPINLYDTKGLELEEDVQETIKKEILDEIENCNR
                     NSLERNDKSELMHVCWYCINTSVARCEETDIKWINELSEKIPVIVVLTQGFPRKKARE
                     LKSSIDDLNLNCKNVIPVLAEQLVEEEDEIVIKSYGLDKLVEVTYQVIPKEVKKAFVN
                     VQKVDIKKKVEESRKWVLGYVGGSGAIGFSPIPFSDAPLLATAQVAMISHITVIFGLQ
                     VDKALLTAIVSSIGGVTSATLLGKTLVSNILKFIPGAGTIAGGAISGSVAALTTTALG
                     MAYISVLEYILNENMKGNEVNNTEIAEKMKDAYKDQLGMLSKK"
     gene            14340..14585
                     /locus_tag="KR231_001988"
     CDS             14340..14585
                     /locus_tag="KR231_001988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0004361.1"
                     /translation="MRSVTVEDGDERFAIEKIYIKSLQRYEVRICLYRDCRDRINKLI
                     PRPVDLTMDKFVALILVGLKAGVLDDDFKQELIKGLA"
     gene            14933..16294
                     /locus_tag="KR231_001989"
     CDS             14933..16294
                     /locus_tag="KR231_001989"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0004362.1"
                     /translation="MKGNINKKDIDLSKITFDKFLEDEGLQNRERDYLYVDDYDNTLD
                     TQEFKLHIIEENTDNTYIDKDKYWYLDLDDSLFEYEEDEDTIAKTLYSLIDIRIKFLK
                     HVEYRKYINLGVIDEEYFDEIKSFLKFYIVAKTKKNELGNSNLKQMAIDIFDKERFED
                     DISDDDMENISEWIGEDQNFKMFYDKVCRDLSNSTQDKEILKLAGIRNNKVKHYKGRK
                     ISRKCKLELKSLTKMWEYETKLTHDANKAHKKIKSNMLEKMTDKNYKNIYEYLNNEII
                     NSNEEYKNIYFYSLELKLANELRKCTLKNLNKIKDIENQVKFISYTIAYIHIVPVLTI
                     REKLSDKLFNILSTNEGKDIEKFTKEVSLIMRIINIECLELLNIVSKNNYYKNFSEKE
                     LEEFKSIYNINNGRKSFENKYKIKVDYNIDDVRKYGEVIKAINIESKKKIVDRIKKKR
                     KSN"
     gene            16484..16801
                     /locus_tag="KR231_001990"
     CDS             16484..16801
                     /locus_tag="KR231_001990"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0004363.1"
                     /translation="MTNFKSVKVELILLIECEEGNRNELEGMIDEGVLNEKEYSLTIL
                     GSTEYEDNARAIYILMNTGGSYEKNLQRLSRLHLKIENLLKDTNVKYRGISLVPNIVK
                     WDK"
     gene            16813..18576
                     /locus_tag="KR231_001991"
     CDS             16813..18576
                     /locus_tag="KR231_001991"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0004364.1"
                     /translation="MSKAINREELIKLYEEIGLNVLDNNTVMNSSNKKICNFLVNIIE
                     QRVIDGKMYLCINAMGINGELLSEVILDSNTINRTTWVIENWGFKYSIDKKYINDFIE
                     LIQHLCMNIKTKYIYDHTGWIYQDNKWIYLHGGGVIGGSDVQVELDESIDNYILPDKI
                     SDINKACEMSLKLVDLIEDDKGIIFSSLVYLSPLIEIISRKIKPPENIVWTYGKTGSR
                     KTAVSKVVLSHFGDFNKKIPATFNDTITAIELKANKLKDSLYLCDDFAPKQDFRDKKI
                     QDSKAESIIRMYGDRVGKGRSSNKLDIKDAKRPRGMILITGEDVICGESSNARLLSIE
                     LNRSSVDLNILTELQNNSHLLGEAMRGYIEWLLSEMGNIDELSNILLYNFKSYRDEIR
                     EQYKDDIHGRTIESSAWILVGFSCMLNYIRDKGVIDKYEDDEYMDRAIKVVERLIEEQ
                     IKLISRNSPIDIFLNTLKESINSKSIRIATLNDQNQVIEDKLEYICGYKDKEYYYFYT
                     DKVYSFIEFENKKRGIHLGISQRQLVKQLRDSGIVKVDSNNDSPKKTIHTKDASDSTG
                     YTTIRPRMLQIERSIIENFQI"
     gene            18639..18794
                     /locus_tag="KR231_001992"
     CDS             18639..18794
                     /locus_tag="KR231_001992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0004365.1"
                     /translation="MTETYKISIGRKDLYSKDYKVVERTDYEKRHTVNISRSLVDILS
                     ILVKEDR"
     gene            18881..20446
                     /locus_tag="KR231_001993"
     CDS             18881..20446
                     /locus_tag="KR231_001993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HBH0004366.1"
                     /translation="MTGKKAVVYARFSSDNQRDESIDAQLRAINEYADKNNIKIVNQF
                     IDRAKSATSDKRPEFQNMIKFCEADTTGISMVIVHKLDRFSRDKYDSAMYKQKLKVKG
                     IRVVSVLENLDNSPESLILESVIEGMAQYYSANLAREVAKGQKENALKALHNGGDAPL
                     GYDVAHDKTYTVNEEEAQAVKIIFDRYIKGYSYSKIIDELNILGYKTKRGNKFGKNSL
                     HGILNNEKYTGVYVFNKTQRKGVDGKRNGHKQKSEEEIIKIEGGMPQIIDKGVFKQAQ
                     DMIQKRKKTPGAHKATTTYLLTGLIKCGECGHAFQGNKRKDSYGNEYVSYRCGCRKQK
                     RECNNREIKRDYLEEFILQELEKNILNDEAIPILSKALNEKLNDKNESNAELLKNLEQ
                     KLDKVNKEISNILNAIMNGIVNSMLKDKLDELEQVKFNLDLKMNELKIENKVVDGVGV
                     TEDQIRGMFSRFKEFVLERNIPECKKFIGDYIKEVIVYKDHIEVIFNVVFCFVDNDIT
                     HDLHIITERGKIT"
     gene            20592..21884
                     /locus_tag="KR231_001994"
     CDS             20592..21884
                     /locus_tag="KR231_001994"
                     /inference="COORDINATES: protein motif:HMM:NF014177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA adenine methylase"
                     /protein_id="HBH0004367.1"
                     /translation="MADIFTVLNYQGSKKRLLDFIYENTQEYIDSDKAFLDICSGTSA
                     VAYNMKRHFTVYTNDSENYAYQISNSIVKNNERYNFSQSDEMIIREKYNINLQRLNNI
                     FNDMVNQEDMLLEQEDADGLIELYSNCPCIWKNNVDIEIEGNTIQSIYDLRKCKRDIP
                     NVLFTLYYSSSYFGIKQSMEIDSIRYAIEFIESEITKSILFTSLFFAMKECVFAKDGH
                     MAQPLNMETGKKRMLRLKARSIYDIFIDKLKEFNTEEFVLSQKENKCFNKDFRTLLET
                     EESIKDEVGFIYIDPPYTDMQYSRYYHILNTVVLYDYPEISLSRGTISKGIYREGRYQ
                     SPLSQRKHALNEIDFLFSFCKENKINVALSYAYPIDTEKQATNRYTASIDDLINVAKK
                     HFGDNVKVVHEEYSHANNRNSDKKNVLEYLIMGIHNKE"
     gene            21887..23506
                     /locus_tag="KR231_001995"
     CDS             21887..23506
                     /locus_tag="KR231_001995"
                     /inference="COORDINATES: protein motif:HMM:NF013704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA adenine methylase"
                     /protein_id="HBH0004368.1"
                     /translation="MDKINKLKERIANIEATNKNDIYSSNLYWSQKPFNICDEIIEHL
                     SEDGDIIFDPFMGSGVTVIEALKKEYKRNAIGCDINDAPIFIVKTLLEKYNVPKIEKD
                     IKELNNKLSKLSTYYSTKCRECGEVVTISKTIFDKENRNAKCELKSIHYKCKECKNDF
                     KGEPNETEISKFFIDEELKNIDDFQFIANSRLAVGEGDTVRTIFSNRNLIVLDKILGH
                     IDEYKNSESYEPMKYILLSILHLSKITDTHSNSQWPLWIPKKDCVEKNVVELFIKNSK
                     KTIKALKLASKYLCENRENVELIKNLDRGKFKLIKDGVQNIEDDVIPNEFVDLIITDP
                     PYMGQVLYSEYMQLYKPFMDLEFELENEIVISSAPARDKGKVLYFDMMNSAFENISRV
                     LKVGKYMCMYFHDSNLDVWDNIIDIMTNNNLKYMGQIHVSKNKNTLKNILSPKKSLNG
                     DCIIFFKKDLNINYDINEVDNIEDKINNIAQAIIDIKGYASTPELYDNGALEYIISNG
                     KLKEISKKYKDLTSIFEQRFNWDKERGVWTV"
     gene            complement(23631..24782)
                     /locus_tag="KR231_001996"
     CDS             complement(23631..24782)
                     /locus_tag="KR231_001996"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0004369.1"
                     /translation="MKKLTIRLKDDFHKDLLDLVAFKNDSINSYVINLIKNDLSKNTN
                     LLRSYDNMIRDNITNVLITQKINELKAIQDGIFKEYKVNDILSNSKIYEVMTANSLNH
                     ILIPGHSGSRDAKDEFGNEFEYKHFKKSSSNHSWTFNDFSDTSIAKLKKAKAVIFAHI
                     NDVDFPYPGKLDWYYSIPGDIMCEYLLKYTQSIQNSRKMINVSPNQLESRLNASKIIP
                     SAQNGVYDKYLSAIYKASSELEELTGVKNLLTSNKFWELIVALELNHQVNPEQGGREG
                     AHDAYDSEGNPYEYKVSKNHAWNFQDISDNVLNKYYNDKAIILAVVDKENIEVEHIYS
                     TEPADVVPLLRKKLQEKINRCLEKGSPIRRLQVSLSKSDLTRVNAKKLY"
     gene            25288..25503
                     /locus_tag="KR231_001997"
     CDS             25288..25503
                     /locus_tag="KR231_001997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3791 domain-containing protein"
                     /protein_id="HBH0004370.1"
                     /translation="MDERKLEFSIFCIEALAEKLNIDSEGVYKLLKHDTDILDNYIIP
                     CYEALHSQSKGYIVEDLMQVLKEKGVI"
     gene            25503..25982
                     /locus_tag="KR231_001998"
     CDS             25503..25982
                     /locus_tag="KR231_001998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433745.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3990 domain-containing protein"
                     /protein_id="HBH0004371.1"
                     /translation="MIVYHGSYCVVKTPSITFSRDSLDFGKGFYVTSIKTQAINWTER
                     FKKRGKKAYLNSYSLDIDKLKENCKVKIFDSYNLEWLDFIIECRNMSDIYMKYDIIIG
                     GIADDKIYNTIELYQDNLIEKDEALKRLKYYKPNEQICITNQNVIDKYLKFRYEEEV"
     gene            25988..26218
                     /locus_tag="KR231_001999"
     CDS             25988..26218
                     /locus_tag="KR231_001999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0004372.1"
                     /translation="MEANKTLLQILYKKIILEFSKQTGKSLEESMDYLYTSETYKLIS
                     EGVSDMHCKGHIYLAQELMLENGLMYHKGYPR"
     gene            complement(26334..27500)
                     /locus_tag="KR231_002000"
     CDS             complement(26334..27500)
                     /locus_tag="KR231_002000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861856.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HBH0004373.1"
                     /translation="MATKRANGEGSIGKYKDGWRSRIMIGYNEDGKPLRKEFYGKTQK
                     EVKDKLDAYKKQYYLSSDISDDKITLEHWFYNWLFEYRIKDLKPKSFERYESIYRNYI
                     KDTDLGNVKLKYLRVSHIQKYYNRLLDSNKSIPTIRQINTKLKTCLSEAEKQGLIQRN
                     YCTMVNIPVEKKENKLEILTLEQQKSFIKAIDGHKLEVLFLLALGTGLRLGELLGLKW
                     FDIDFKKSNLTVKRTLQRTYFIDKTGNRELKVLEQGPKTSNSYRTVPIPKDVLNKLKE
                     HKVNQNTDILKAGELYINNNYVFCNELGIPIDDKRPLRNLKSILNSLNIEPIKFHGLR
                     KTYATRLFENDVPPKTVQVLMGHYDISITLNIYTQVMEDKKVEAVEKLDKIFSL"
     gene            complement(27490..28242)
                     /locus_tag="KR231_002001"
     CDS             complement(27490..28242)
                     /locus_tag="KR231_002001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fic family protein"
                     /protein_id="HBH0004374.1"
                     /translation="MNKSYIPKYTHKFPTNIPHGDKKYTLTYIRRMISEFVYDMGNLE
                     NNPFTFPEVQTLLDGITVGGHKLSDQNQILNIKSSWDYVIKLSNKENLSLNKDTICSI
                     HKIVAKDEALIVGDFRNGNIGIAGTTQYECIEATLLNDLFVNDINIINKITNPLEKAI
                     IINLWLSYCQFFYDGNKRTARLTSNLILINNDIGVLSIPAKHKQEYNTLMLNFYETLE
                     ADEVIKFLLEKCITFFDGYNYKSYKELFKNGN"
     gene            complement(28334..28825)
                     /locus_tag="KR231_002002"
     CDS             complement(28334..28825)
                     /locus_tag="KR231_002002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891546.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBH0004375.1"
                     /translation="MMNNTIGEKIKQYRKSINMSRDELANKIGCSVHAIAKYEQNQRM
                     PSLDMIRKIATALSIAINKLIVEENDLDTLTNNNINLKVFDKELDLVIHILENYGYDI
                     KTDYKKKFEITDNADTIKPINLNFSDFKDFSKNLNWVINGLVENFIQENSNGLIEDED
                     EEY"
     gene            complement(28822..29020)
                     /locus_tag="KR231_002003"
                     /pseudo
     CDS             complement(28822..29020)
                     /locus_tag="KR231_002003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729178.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(29077..29838)
                     /locus_tag="KR231_002004"
     CDS             complement(29077..29838)
                     /locus_tag="KR231_002004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBH0004376.1"
                     /translation="MQIGKNLKKIRKQKELTQIQLAEISGISRNALINYENDKRIPSI
                     DTLSKLAKALKIEKTIFYFDIENEVMTNEDVLYLLQSLFPEEYYSFDEFLNAISNLME
                     DDIRITSSLLLGAWSDKDQYYKLGEKLELNENQVYNWILSDCISNTELDFSLHPDDIK
                     EIIKNDVLTKQSIDELLDIGLSEESIETIYDYFSDSTDNGSNIRLKKLISQKENITIK
                     NNDYFKLLQENNELKEKNEKLENTLKEIKKLLTKI"
     gene            29985..30185
                     /locus_tag="KR231_002005"
     CDS             29985..30185
                     /locus_tag="KR231_002005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBH0004377.1"
                     /translation="MGINLKIFRIKKGLKQQELADRVGISRYYLSNLETGKANNPSND
                     LMIKLSRALDTTVEELFFSKED"
     gene            30189..30503
                     /locus_tag="KR231_002006"
     CDS             30189..30503
                     /locus_tag="KR231_002006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0004378.1"
                     /translation="MKENNNLEVLKTLQATLNIIVKNEEEAQEKKQGYKIIENAKRNK
                     AELITCKEASKLYPIGESKFRQLCHSKNKGFPCIWINNRVYIIKNKLDDWFIENANGI
                     KL"
     gene            30525..31268
                     /locus_tag="KR231_002007"
     CDS             30525..31268
                     /locus_tag="KR231_002007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0004379.1"
                     /translation="MSNKGWIKLYRELLDKSIWKDIKPERKVILITLLLMASHKENHV
                     FIDNKKIKIKFGQFISSYSKIAERCGKGVSYQMVRSCLLVFKNAGFLTYETTNKYIVI
                     TIENWELYQENIENQQPNQQTINNQSTTIKNIKNENNIIYSEIISKFNSTCIELSKVK
                     KLTDTRKRRINSRIKEYDKETVLEVINIVSKTSFLNGNNNTGWKANFDWIMNSSNFTK
                     ILEGNYNSKEIVINKETGIYNPDDSQLKW"
     gene            complement(31974..33887)
                     /locus_tag="KR231_002008"
     CDS             complement(31974..33887)
                     /locus_tag="KR231_002008"
                     /inference="COORDINATES: protein motif:HMM:NF020926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1998 domain-containing protein"
                     /protein_id="HBH0004380.1"
                     /translation="MSIKLDDKTHNLRINQATSVFGPGAMLDFIDQTLMTAHPNYWTN
                     TIKIQDDRLQATLRVNELRTPPTIDDRSSVPFVRFPRWYFCPKCRKFMPIEDWEKLYK
                     NAHKDKPMKIPICLTCSTKKSTKQLVPTGIITICEHGHIDDFPWVKWVHFRNKSGRKE
                     ICENPQILMKTGKSNLGLEGIELECSCGAKANMKGAFMRLKSSKSNDYGVPSEYKEMF
                     KCSGNSPWYNKKVNKCTKYSFASQRGASNVYYPKIESSIIIPPYSDTLNSKVLSSKGY
                     DTFKKFLDRAIKKNKLERFMDEDFEDFASDIAKETGFDTDKVSIVLKDLLPFEDSSPS
                     TTTRNQYREEEYEALIGNIDAKSKKTNDFTIEEQNLSDYDIPNFSKIVLVKRLREVRA
                     LTGFSRVNPPDNNIFGEEDIDDSCNDTKVISLRSRDCKKSFYPASEVRGEGIFIEINN
                     DMVKSWISSNPKIQDNASILNSRYNKDINVNDKAYRKITPKFLLLHTLAHLIIRELSF
                     VCGYATSSLRERIYCNNSENEKVMSGILVYTASGDSEGTLGGLVRQGMHDSLPSILNS
                     ALNRALWCSNDPICIDSTGQGRNSLNLGACHSCTLLPETSCEEYNLLLDRSMLIGDMD
                     NRDIGFFKNLILI"
     gene            complement(33889..37416)
                     /locus_tag="KR231_002009"
     CDS             complement(33889..37416)
                     /locus_tag="KR231_002009"
                     /inference="COORDINATES: protein motif:HMM:NF012493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase"
                     /protein_id="HBH0004381.1"
                     /translation="MNCSELRDKTLDLVRKELLGPGSEDLCENIKYEIITDSPIERYS
                     TGILYPLNNNIDVSNTSEYDGEDNVFTSDDTQNELDRAISMSNETLPSSMGMTFFLKK
                     DAEVINFRVNYATYRNALYTDCHVKYTGDDFYSSNTINEYVELRGSFLYLKQKLTSEK
                     VYNLLKKHDLLDNAEAKFVLYKLANQCPDDENKTGGYVRVPHENLIVSIDMDKNYIKK
                     PISKDLDIVLSKRIYSNDFVSITCMLVNSQSGPKKYNNTIFQPELMVLAEDNNDLEFI
                     DIFTAGSVNTFKKLDSEEISLDLLYRNKKTFATGHGVAIDQDIQNDALIKLCTEFIPH
                     FEVPKLDFNVDELSDVSRELLSMKNLSDISDLSKDKKIYFLYKFVDAYDIWIDDLEED
                     SKDLSDVFKDVAYEHIKNCRDTKSRMLEGINLIKSNDEVYRAFSLMNRAILMQRCHSI
                     HITDRLPGSNNLDYIDYSNDNSAWRPFQLAYILTCLSSIENPDSKHRDLVDLLWIPTG
                     GGKTEAYLGLSAFTIFLRRIRNKENGNGTAIIMRYTLRLLAAQQFIRASILICACEII
                     RKENKSELGKKEISIGLWIGSDQTPNFNDEAEEMLNNLTGNNIKFRSSINSEYELDNL
                     KSKYNKFQLLKCPWCGTKLVKEWDKTSKKAVGDWGYRIKSRPKKFYLCCPEEDCSFED
                     MLPIQVVDEEIYNNPPTLLFGTVDKFAMITWTTEVASLFALDDDNSNLSPELIIQDEL
                     HLISGPLGTMVGLYETALDAMCSYKGIKPKIIASTATIRKAQNQVKNLYNRNVAQFPP
                     PGLTSSNSFFVKEMPLSKKRGRLYVGVIPSGKTQVTVEVRLMSALLQRLKMMENVELN
                     LLDKYWTLVSYFNSIRELGKCSTLLNDDIKDNMERLCKRVSAHPYQSLRNLNEQRELT
                     SRLTSTKINTTLDELSNTLTSNNLTVDTLLASNMISVGVDVDRLNLMVVVGQPKLTSE
                     YIQASSRVGRSNEGLIFTLYNPTKTRDRSHYEQFFSYHQSFYKFVEPTSITPFSEPAR
                     ERGMHAVLISMIRHILGLQANDLASRFSKNMDGVEDLKNFIIDRSIDIFRENNQNADD
                     NIVNEFKSEISSELDIIMDLWHDKAQISDKDNLLHYYKRPSKFDNKIYNNLLIPYDKD
                     VITNEKQTLNSMRNVDKQCTVEIIELEEN"
     gene            complement(37434..38396)
                     /locus_tag="KR231_002010"
     CDS             complement(37434..38396)
                     /locus_tag="KR231_002010"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0004382.1"
                     /translation="MNQINSARNKIEKNNKIYNLLDIKPFKPTYETNKLEAYSTDSPI
                     SDDDSMDEYISNYKFDINLNEIILSLSINQGIYNSKKEHVTSFMISDNNEYIFCTKKA
                     IAYSIDWDKKSVRKKKLSEAKVNDWFLFVDDYLNEEGELVINVIQKLLELNLLPSHYL
                     DDYKLTNSWKSELKNYISYSKYNYNDVSNSLAVLGEKINPITIKNWVTNKRLIGPIYL
                     KTFEKIFKVIDSKLDHTEVYDATKSIRSLHTKIKKSIDTFVSDNFFSSKSDIIKDEVS
                     AVVLSMLGNTNDYVTPVQIREIHSCDKYLSPHLVNKVLDLYSVY"
BASE COUNT        15318 a         4262 c         6082 g        12761 t
ORIGIN      
        1 tataatatgt aatatttttg ttttgaaatt tataaattag tattactggt tagagttagt
       61 ttagtattaa gtatattcga agtagttttt tagctatttt catacattta tattacttaa
      121 ttatatatag cctaactaac ttaatatatc agtgaaatat tgactaaaat gcctaaatat
      181 gttatcatac aagttagtca aataatttgg caacattaaa tatttagtaa atttctaaca
      241 tttatggaac aaatttctag caaagaaggt gagatttata tggctggtaa aaaaatatta
      301 gcaacaaaca aaagagcaag acatgaatat tttatagaag aaacttatga atgtggaatt
      361 gaattaaaag gaacagaagt aaaatcaata agacaaggca aagttaacct aagtgatgga
      421 tttgcatctg tagataatag cgaagtattt ttaaaacaag ttcatataag tccatatgag
      481 caaggaaata tattcaatgt tgattcttta agagttagaa aactattact tcataagcat
      541 gaaataagaa agcttattgg agcaactact ataaaggggt attcacttat accacttagt
      601 ttgtatctaa aaaacggtaa agttaaagta gagattgcct tagcaaaagg taaaaaacta
      661 tatgataaac gtcaagatat ggctaagaaa gatgcacaaa gacgtataga aagagaaatg
      721 acaggtaagt attaaactag ataaaactgt attttttaga ataaaattct ttattatcta
      781 gaacataaca ttgattttta ttcttaaaag tattatatta tatatacatt aaaaatttaa
      841 taaaaatggt gataaagttt gagaaaagtc tactggacta taaactactc aagggggcgt
      901 aaaggtttcg acgtgggttt ggaacttgag gctgcatgtc gtgttactct gggtcacgta
      961 aaaactgggg aactttaaaa taaacgcaga cgataatttc gcgatagcag cctagttgct
     1021 gctcgtccct cttagtcctc ctgccgacta agactggacg tcattatgca gggaactact
     1081 ttaggggtgt ctcgacttga agtagattaa ttgggactgg ctaagcatag agcctgccac
     1141 ttggcgctat gtgaggtgag atattagtga agttggctaa gcatgtagat gcagcaagga
     1201 aaagatttgc ggacaggggt tcgactcccc tcgtctccac cattgaaatc cacgaaaaca
     1261 tattgatagt ttagtcaata tgtttttttt gtgccttgaa atgatataat tataatataa
     1321 actaatgtaa aatttaacta aaaggagata gtataagtga gtatagataa taattttaac
     1381 catgttgcat ttctgtggaa tatagcagaa agtttaagag gtacatataa agaagaagac
     1441 tatagaaaag taatgttacc actaatagta ataagaagat ttgattgtct attagatgat
     1501 tatgatagag aaataataaa atcagtatac gaagaatacg acttcttacc agaagaagaa
     1561 agagatgagc tagtaatagt agacttaaaa gaaaatcacg acataaactt acaattttac
     1621 aatgtaagtg attttacatg gaaaaaacta ttagatgata gtgaaaatat aaaatcaaac
     1681 tttgaagaat atctaaacgg attctcaaac aatgtaaaag aaataatagg taaatttaaa
     1741 tttaaagatg aaataaatca attagataaa aaagacaagc tatatgcagt tcttagcaaa
     1801 atgtatgaag tagatctaca tataaactca gtatctaaca ataaaatggg atacatatac
     1861 gaagaaatgt taagaagatt tacagaaaac tcagcagcag gagagcaata cacaccaaga
     1921 gaagttataa gactttgtat ggaaatacta tttatgggta aagaaaactt ccttacagaa
     1981 gaaggaaaag taatatctat agcagacttt tgttgtggta ctggaggaat gctttcaata
     2041 gctgaagact atgtagaaaa aataaatcca agtgcaatag taaatgtata tggacaagaa
     2101 ctacttgatg aatcattcgc aatatgtcag gcagatatgc taatgaaagg gcaaaatcca
     2161 gataacataa gacttggaaa tactttaaca caagatagat ttaacggaga aaaaataaga
     2221 tttttaatat caaatccgcc ttttggtgta acttggaaag acgaagaaaa gaaagtaaaa
     2281 gaagaagcag acttaggttt tgatggaaga tttggagcag gtactccaag agtaagtgat
     2341 ggttcattac ttttcctaca aaatatgata agtaaaatgt atgatgatga agaaggaagt
     2401 agaatagcta taatatttaa cggaagtcca ttatttacag gagatgcagg aagtggagaa
     2461 tcaaacatta gaaaatggat aatagaaaat gatttactag aaggtataat agcactacct
     2521 actgatatgt tctacaatac aggaatagct acatatattt gggtacttac taacaaaaaa
     2581 gaagctaaaa gaaaaggtaa gatacaactt gtaaatgcta gtgaatatta tcaattaatg
     2641 agaaaaagct taggaaacaa aagaaaagaa ataagtcttg aacaaataga acaaataaaa
     2701 gaaatatatg aaaaatttga agaaagtgaa aatagtaaaa tatttgataa cgaagatttt
     2761 ggatatagaa aagtaacaat agaaagacct ttaaaactaa gctttaaagt aaacgaagaa
     2821 gctatagaaa atgtaaaaaa tactactcaa tttataaatc ttgcagtttc taagaaaaaa
     2881 gatatagaag ttaaagaaaa agaagaagct gaaggaaaaa taaaacaaga taagttaata
     2941 aaacttttag aaagctttga caatacttta gagtatatgg acagggataa atttataaaa
     3001 gatttaaaag ctaaatcaaa agagtttgat atacaacttt cagcaggact tataaaggct
     3061 atagttaata ctattggtgt aagaaatgaa gatgcagaag tttgtaaaga tagcaaaggt
     3121 aatatagaaa gtgatagttc attaaaagat actgaaagta taggtcttaa agatgatgta
     3181 tatgagtatt ttgaaaagga agtaaagcct catgttaatg atgcttatat agatgaaagt
     3241 agtataaata atataggata tgagatacca tttactagac atttttataa gtatgaagag
     3301 ttaagaagtt ttgctgagat tatgaaggaa gtagaaagtt tagaaagtga gatagcacta
     3361 aagataagga aggtgctagg gtaatgggat acagatatag aagtgatgat gagttaaagg
     3421 atagtggagt tgagtggtta gggaagattc ctaaggattg ggaagtcaga caattaaaaa
     3481 gggtactatc agatagaaaa gaaaataatg aacctataaa aacaagtaat atactgtcat
     3541 tgacaataga aaagggagtt attccatatt ctgaaaaagg tactggtggt aataaagcta
     3601 aagaagattt aacacaatac aaattagtat atccaaatga tattgtatta aatagtatga
     3661 atgtaattgt tggtgcagta ggactatcaa aatattttgg gtgtgcgagt cctgcatatt
     3721 atatgttata taaaataaat gctaacgatg atataagatt ttataattat atttttaaat
     3781 ctaaattatt ccaggatagt ttaaaaggat taggtaatgg aataatgatg aaacaatcag
     3841 aaacttcagg taagttaaat acgatcagaa tgagaattcc aatggaaaaa ctaagttcag
     3901 taaagatacc aattgctttt aacttagatc aagaaaaaat agcaaacttt cttgatgaaa
     3961 agacttcaca gtttgattca attatatcta agaaagaaaa gttaatagaa agattagaag
     4021 aagcaaagaa aagccttata agtgaggttg ttactggtaa ggttaaggtt gttaagactg
     4081 atgatgggta tgagcttata aagagaagta gtgaagagat gaaggatagt ggagttgagt
     4141 ggttaggtga gatacctaag gaatgggata taaaaagact tagattttta ggaaaactac
     4201 aaaacggtat aagtaaaagt agtgattcat tcggttatgg ttatccattt gttagttata
     4261 gtaatgtata tagaaatata gaattaccac atatagtaga aggtctagta aattcaactg
     4321 aagaagaacg taaaatttat tcagtagaag aaggagatgt attctttaca agaacttcag
     4381 aaacagtaga agaaattggt tttgcttcta cgtgtatgaa aactattgat aattctactt
     4441 ttgcaggatt tttaataagg tttagaccga atgataaaag actatacaaa ggattttcta
     4501 aatattactt tagatgtgat ttaaatagaa aatattttgt aaaagagatg aatttagtaa
     4561 ctagagcatc tttatctcaa aatcttttaa ataatctttc tgttgtattg cctaagtatg
     4621 aagaacaagt tgagatatat aatgcacttg aattaaaagt tagctacatt aatttatcga
     4681 ttaataagtt aaagtaccaa atagaaaaac taaaagaagc taaacaaagt ttaataagtg
     4741 aagcagtaac aggaaaaata gagatactag attaacttct agtatcttaa tatagatata
     4801 gattatacat acaaagttaa ataaaaggga gaattaatgg ataaaaatat atttcaaatt
     4861 aatataaata cagatgtact gataagatta aggaatcaaa taaatgaaga atattatata
     4921 tcttatagaa aagaatttta tgataaaaat aataaaaaac atcgcgcttg ggataaaata
     4981 tgtgcaataa tggataggct tgacgatact gtagattatt taaataaact caaattaaat
     5041 acaggtaaat atagacgaag tgcatttgac ttctttgaat ttatgaatca ggcttccgta
     5101 gtaatggatt gtataacaca tcttgcaaaa atatttgaag taccatatga agaagttgaa
     5161 acttcaactg aaatttttaa tgagcttgga aaagagggta aaggtacaga taaaaaatac
     5221 tttgaatatc tacgttcatt gtgttcagtc catccaatgg aaactagtag acacaaaata
     5281 taccaagaaa atagttttga atgtagtcct tatgtagttt ggaatgataa aagtatatgg
     5341 actaatgatg ctagcgattt atatgcagtg gtatacacaa gtaaagataa tgatagtttc
     5401 aaaagaattc atatatatat gaatcaaata tttgagtatg taaaaagaag agtaaatttt
     5461 attgaaaata taatagaaca tatagaaaag tatcaacaag aaataattga aatttttagg
     5521 aatactccaa taaagaaaga agaagatttt gaaagttata tagattattt aagaaatcta
     5581 aaaaaagaga tagaaataag atatggtaat gattcttttc atgaattaaa ctaccttata
     5641 gaattatttg atttgccatt atcaaatcct gataatgaag agaagatgaa cttatataaa
     5701 aatgctttaa aatatgctat caaatttgag cataatagta ttcaaaatat gacaaatgaa
     5761 ggttataaga ataatggaat attatatcca caagtgaata taacaactac attactagaa
     5821 gagctaattt cattaaatag tggtagtgag gagagacgta agtacagata tgcaatagaa
     5881 aaaacatcat atctaagcta tgatagttgt tggagtgata gagaatgggc atatgatcaa
     5941 atagatgata tgatgccttt tttagaaaga tacgtaacat ttgataaagc tcaaagtgat
     6001 tttgagcatt atgtattggt aaaactagca ctttatttag agtgcttaga aaatgaatgt
     6061 ttaataaata agaacgttcc taatgataaa aagtttcgta ttaaataatt atagctaata
     6121 aaatagggag agggaggata ttatgttacc aaaagaaaaa cacctagaag aatctattga
     6181 aaatcattta gtttcaattg gatatgaaca aggtcattca caagaatttg accttgaaaa
     6241 ttgcttattt gtagatgatt tatttagatt cttagaaaat actcaaaaag aattactaga
     6301 tgagtttaaa tacaacaggg gaagtaatta caaaaaagct tttatagatt tattaaattc
     6361 aaacatcaaa agaagaggtc ttataagtgt acttagaaat ggtgtagaag atataatgat
     6421 gaacggaaaa tttcaattat tctacaacaa accaaatcta actactaata aaacagcgta
     6481 tgaaaattat aaacaaaata tattcaaaat aacaagacaa ttaaaatata gctcaaagca
     6541 caacaatact ttagatatag tattatcttt aaatggattt cccgttatag taatggaact
     6601 taaaaatcag tttactaatc aaaatgtgta taatgctata aagcaattca aaaaagatag
     6661 aaacccaaaa gaaactttat ttggatttaa tcaaagagtg ttagtatatt ttgcagtaga
     6721 tactgatgaa gtttatatga caacagagct aaaaggagat aaaacattct tcttaccgtt
     6781 taataaaggt aacaatagag gtaagggaaa tcctgtagta gaaggaaaag aaaaaacttc
     6841 ttatctttgg gaagaaatac ttactaaaga tagtttactt gatattataa aaagatttta
     6901 ctttattcaa gaagatgata aaggtaatca aagagcaata tttccaagat ttcatcaatt
     6961 agatgcagta aggaagatag tagaagattt aaagataaat aaagtaggta aaaattatct
     7021 tatccaacat agtgctggta gtggtaagac taacactata gcatggactt cacataggtt
     7081 atcaagtctt catgatgaag aaaataatgc tatatttgac tctataattg tagttacaga
     7141 cagaaaggta cttgataaac aattacaaaa tgctatatat caattagagc acaaaaacgg
     7201 acttgttgtt aagatagatg aagataaaaa ttcatcagac ttagcagatg ctattgtaaa
     7261 tagagcaaag attattataa ctactattca aaaattccag tatgcactac ctaagataga
     7321 acaacttgat aaaaggcgtt atgcagtaat tatagatgaa gcacattctt caacatctgg
     7381 tgaaaatatg aatgcattaa aagaaacttt agcaggaaag actttagaag aagctaaggt
     7441 aattgatgcg gaaaatgaaa agaatgaaaa gtctagtata gataagatga atgagcttat
     7501 agagaaaaga acaaatttag gaaatataag tttctttgct tttacagcta ctcctaagaa
     7561 taagactatg caagtatttg ggaggatagg tgaagatgga ctacctcatg aatttcattt
     7621 atattctatg aaacaagcga tagaggaagg atttatatta gatgtactaa aaaactttat
     7681 gcctataagt gtttattaca aagtaggaaa gaaaattatt gataaccctg agtttgataa
     7741 gggagaggct aagagggcta taaataagtt tgttagttta aatgagcaca atataaggca
     7801 aaaggttgaa actatagtag atgattttgt agataatagg tctatgtggt tagaaggtaa
     7861 agctaaaggt atgatagtta ctgcaagtag attacatgct gttagatata aactagctat
     7921 agaccaatat ataaaagaaa aaggatatga tatgaaagca cttgttgctt tttctggtac
     7981 tgtaaaagat ggtgatgatg agtatacaga ggtaggtatg aataaggaag tagcaccaga
     8041 tattactgat tcaaatttac ctaatatatt tgataaaaat gaatttaagc tattaatagt
     8101 tgcagaaaag tatcaaactg gatttgacca accaaaactt tgtgctatgt atgtggataa
     8161 aaaactagat ggtgttaaaa ctgttcagac tttatcaagg cttaatagaa cttatcctaa
     8221 taaacaaaca tttatattag atttccaaaa tagtgtggaa gacatacaag atgcatataa
     8281 gccatatttt gaaatgacta atattgataa ggtaacagat ccaaatgtag taaatgacct
     8341 ttggtatcag ttacatgaat atgcagtata tactgatgag gaagtaaatg attttacagt
     8401 attattctat aaagagaaaa gaacttcttc tcaagatgct aagatgaata atttaattga
     8461 taaggcagtt gaaaggtatt gttatttaga agaagatgat gaaaaaaaat ctgatgagtt
     8521 taagaaaaaa tgtcaaaagt atattacttt ttataatttt ttaattcaga tttatcctat
     8581 aaagaactta aatcttttaa gattgcaagt ttatttagta gcacttttaa agaagttacc
     8641 taaaaagagt aaacaaagaa tagaccttga tgatatgtta agccttgatt attataaatt
     8701 gcaaaagctt ggattagatg ataaaaaagg aacggatata tccttatata atggagaagg
     8761 tgagttagtt ggtatatctg aaactgcgac ttctcgtgta agtgaagctg atgaagagta
     8821 tttagaggat ataattaaaa aaataaatga tgtttttggt gtaggactta cggaagatga
     8881 tagaattatg ataaatactt atgaagagat gtttaagaat gacaaggata tcatggatat
     8941 agctaaagct aatagttatg aagatttagt tagcactttt ggtaagaagt attttaagag
     9001 aggtatagtt aaaaccaaaa atagaaatga tagattagtt aaggagatat taactaataa
     9061 taatttacaa aattatatga ttcattattt agctgaaaag atatatgaag aggcaaatag
     9121 ataagatacc tatagagagc taattaactc tccataggta ctttattatg agctattgta
     9181 tattattcat cttctaaagg tgtagcaatt ccttttaatt ctaaaaactt taagtctaaa
     9241 tcaagaataa gctctatagt atctctatct atagaaacac cttctttttt acactcagta
     9301 agtataaaat caacttcttc ttcaaactct ataaatggtt tatcgttatt catatttttg
     9361 ctcctttgat taaatataat gtatttactt taaattatat caaagaagag aaaaaaataa
     9421 cattatttgt aaaaaactat atatatataa tatatagttt taccatatat agataaactg
     9481 tttttaatta aattataaat atatattata ttaatgaatc tatattaaat agatagttga
     9541 gtaagtagta ataccaaaaa tattaaaaag agatgttggt agaaatacga acatctcttt
     9601 tttagtgcaa aaaattaaaa ggaggaagtt aatatgatta aattatggaa gaaagaagat
     9661 ttaaatttat tattagaata tccaaaggaa gtagttgaaa atgttgataa cgtcattaat
     9721 attcttgatg aaaactatgg atgtaacaga aaattaacag atgatggtgg atatgtgtgt
     9781 ataattgagg atattaaaga agtagaaaac ttaaaatcaa atatattaaa ggggttagta
     9841 gaagagttta gtgatgtaat atatgaagat gaagttaata catataattc aacactatac
     9901 ttgttatcta gtgattatag tgttactgta atttctaaaa atgaagaaac tgagtactta
     9961 cttaaataag catatacatt gataaggtgt atatgcttat tttaatttta ataaataaag
    10021 gagaaaagca gaatgaataa aaagagaact cctgccaaga gagttgatat agttttactt
    10081 aaattagtaa aagaacgtag tgttctatat gaaactagaa aaataagtaa tctttatgat
    10141 gcttatagat tagcaaagaa ttttttataa atagtgctag agaaaagttt gtagtggtat
    10201 gtttagatac aaagaattgg ccagtagcat agaggttgta agtataggca ctgtaaattt
    10261 atctatggta tatccaagag aaatatttaa agtagctata ttaaccaatt catctgaaat
    10321 gatatgcttt cacaatcacc caatgggtaa tactgacttt agcaaggaag atagttataa
    10381 ctaatatgct acagaagcgt ggagaaatat tatgcattga attagtagat acatatagtt
    10441 attgtagatg aggataaata ctttagcttt aaagaaaact gtaggatata agagtcttag
    10501 cttaaataaa ttaggctaag gctttttcta tgttccaaaa caattaaaaa taaatcaaat
    10561 ttaggttaag cccggaaagc ccttgaaaaa aataatacat ataaatttaa aactaaatag
    10621 gagttgtaac atgtttaaaa aagaaaatag gtatatgaca aaagagatag ctgaaaatct
    10681 accaattgaa atagctatac tactatggaa tttaatagat gacttaacta cagaaaaaga
    10741 ttatctacaa ctatttgaaa taaatcctat aggattagga gtagttgaga tagttcataa
    10801 gcaagaagta cctgaatatg aagctaggat atatatacag aatgataaaa ttaaagataa
    10861 attaaaaata tatgttatag ataatgttga atatagaaca atgatgtttt caaatgaata
    10921 ttagttaatg attaaaggag agagagtaat atgataaata ataaatctga aataattaat
    10981 aagttatttt tcaatgaatt aaaagagtta atagataaat acaacaatat agatgataaa
    11041 actgtagatg taatagaaaa gatatttaca tgtatagaag atgaagaaat aaagaattac
    11101 ctaataagag ataattgtaa gctacaagag ctagtaaata catacaataa acttgaagat
    11161 ttaaacatag atgaagctat attctttgct tggtacaact taactataaa tacaatatct
    11221 atagataaag caagtgagta ctacgatgat ttaactacaa gtaactatat agaagtagaa
    11281 aatcatataa tatatacaaa tgaaagagat ttaaggaagt atgctgaaga tgaattagaa
    11341 actatgttaa gcatggaaca tcatatagat agattactac ataaagacat gttaatagat
    11401 atgtggttaa acaatacttc aaaagaagaa gtaatagaag aaatattaat gagtgatgat
    11461 atagaagata tattgaattt atctccagaa tatgcattta cattagctaa tggaatagaa
    11521 tatagatact cagaaaaaga agaataaaat aagtatatgt actgaaaaat acgggcttta
    11581 agggcttata cattaaagta catatttgaa aataccatag attttacaag agaaaatcag
    11641 aatgaaactt tttcaaatac tagttattat taattagtgc tagaaaagga ggtggagtga
    11701 tgactaacaa caataataat tgtgattata agggcatata tgcagatatg gttgaggttt
    11761 tgggtgaaga aatagtcatt aaattacata agtattatcg tggacaacaa ataacatttc
    11821 caatgaaact atattctatt gaatatgtgg aacgatatat agtgaagaat tatagaacaa
    11881 aaacaataaa agaaatgtgt agagagttag gatatacaga gggatggata aagcaattaa
    11941 ttaataaaaa tagattaaat tcaaagtaat tagagaagga gattgacagt agatatgata
    12001 ttaacagtat tagcaatact tatggggaca ggtatatttt ttctgattaa ttcaatgcta
    12061 gatataacgt attttggatg tggcccaata ggatttttat ggtttggatg ttttattgtg
    12121 tcatatgcaa tattaacatc attaggtggt atagttttag gattgttaaa gtggatagta
    12181 ataggattga ttatactatt tgtaatagga ttaatagcga ataagataaa tgattaaatt
    12241 actgtagatt attttgataa aataattatt taatatattg aggcattaca tgatagaaga
    12301 ataaatataa atgacttaaa atctttaact taactaaaca aaaaatatat tatttattac
    12361 aaaaaatgac aaaaaaatta aatattatat tgtattatga caatataaaa cattggagtt
    12421 tataaattag gaggaatatt ttatgcaaga ttttgatttt ataagtgaga caataaagaa
    12481 atttcaatcc gatttagaaa acatggataa ggtaaatata cttgttgtag gtaaaacagg
    12541 agtaggtaaa agtacattaa taaataatat atttagagaa gaattagcag aaactggaat
    12601 tggtagacct gtaacacaac acttgaaaaa aataagcaaa gaaggattac caataaattt
    12661 atacgataca aagggattag agttagaaga agatgtgcaa gagactataa aaaaagagat
    12721 attagatgaa atagaaaatt gtaatagaaa ttcattagaa agaaatgata aaagtgagtt
    12781 aatgcatgta tgttggtatt gtataaatac atcagtagct agatgtgaag aaactgatat
    12841 aaaatggata aatgagttaa gtgaaaagat accagtaata gttgtattga cacaaggatt
    12901 cccaagaaaa aaagcaagag aattaaaatc tagtattgat gatttaaatt taaactgtaa
    12961 gaatgtaatt ccagttttgg cagagcaact agtagaagaa gaggatgaga tagttataaa
    13021 gtcatatggt ttagataaat tagtagaagt tacatatcaa gtaataccaa aagaggtcaa
    13081 gaaagctttt gttaatgtac aaaaggtaga tataaaaaaa aaggttgaag agtcgagaaa
    13141 atgggtttta ggatatgtag gaggatcagg agcaatagga ttttcaccaa taccattttc
    13201 agatgctcca ttattagcaa ccgcacaagt tgctatgata tctcatataa cagtaatatt
    13261 tgggttacaa gttgataaag ctttactaac ggcaattgta agttctatag gaggggttac
    13321 atcagctact ttactaggaa aaacattggt atcgaatata cttaagttta taccaggagc
    13381 tggaactata gcaggtggag cgataagtgg ttctgtagcg gcattaacaa ctacagcatt
    13441 aggaatggca tatataagtg tattagaata tatactaaat gagaatatga aaggtaatga
    13501 ggttaataat actgaaatag ctgaaaaaat gaaagatgca tacaaagatc aattaggaat
    13561 gttatctaag aaataattaa ttcaagataa agtataagat taattatagg gaaaaagtaa
    13621 aatttaaagg tatatttggt aaaacataaa caaaaatgat aatggcgtca atattatttg
    13681 ttgtcatatg tagtagctta gtatatatat tattgagtga taggtttaat cataagttaa
    13741 tttacttaga gaaagatata ttagatttaa gaaataaaaa tttgtaacta gctaataaag
    13801 gatcagtata gaaacagata aacaagagga taatgtagat attaaatcta aaaacactaa
    13861 taatgaagaa tataaaactt caaaactatt taggcactag atagagtatt tgctataatg
    13921 aataagctaa tagagaaatt aaaacgttta tagtaagata actaattcaa atacatttag
    13981 tggacttcaa ggaacatttg atacactatc aaactatggt agctaattga tagaccaatc
    14041 atctaaattg aatttatcaa atgttggatg gttagaaata tctgatataa ttacaagtat
    14101 aggaaaggac tattagattc tgaaaatatg tcatttgaag cattaaatat aatgggaaaa
    14161 ataggaaaat ttataaatta tattgaaatt aattatatta actaattaaa tattgataca
    14221 taatgccttg ctacagttaa atgtggcaag gcattatttt tgtaaagaaa ggaagaatta
    14281 acatggcgaa gcaaagtaaa gaggaactat ttgaaaaaga aactaaatat tgcaagataa
    14341 taagaagtgt aacagtagaa gatggagatg aaagatttgc aatagagaaa atatatatta
    14401 agtcattaca aagatacgag gttagaatat gcctgtatcg tgactgccga gatagaatta
    14461 ataaacttat tccaaggcct gtagatttaa ctatggataa gtttgtagca ttaatactgg
    14521 taggattaaa ggctggtgta ctagatgatg atttcaagca agaactaatt aaaggtttag
    14581 cttaggaggt agaatatgac aatagaagag tttactagtg gagtaatgtt tgggatttca
    14641 atttttagtg cagtattaaa gcaagtatta gaaaataaaa aatagtatac aggaggtatg
    14701 agtatgattg gatttataat aggaagtata ataggaattg gactatgtat tagtatagag
    14761 atactgatat cgaaaaatgc cataatatac taagttatat ttaaattatt aatagattca
    14821 tatataattt atttaagccc ttaaagccca gataagttat attaaagtaa agtttgtatt
    14881 tatgtaaatt aaataatata tattattata aatttgaaag gactttataa atatgaaagg
    14941 caatataaac aaaaaagata tagatttaag taaaataaca tttgataagt ttttagaaga
    15001 tgaaggatta caaaatagag agagagatta cttatatgta gatgattatg acaatacttt
    15061 agatactcaa gaatttaaat tacatataat tgaagagaat actgataaca catatataga
    15121 taaagataaa tactggtatt tagatttaga tgatagttta tttgaatacg aagaagatga
    15181 agatactatt gctaaaacat tatatagtct aatagatatt agaattaaat ttttgaaaca
    15241 tgttgagtat agaaaatata taaatctagg agtaatagac gaagaatatt ttgatgagat
    15301 taaatcattt ttgaaatttt atatagtagc aaaaacaaag aaaaatgagc taggtaattc
    15361 aaatttaaag cagatggcta tagatatttt tgataaagaa aggtttgaag acgacatatc
    15421 agatgatgat atggaaaata taagtgaatg gataggagaa gatcaaaact ttaaaatgtt
    15481 ttatgataaa gtttgtaggg atctctcaaa ttctacacag gataaagaaa tattaaaatt
    15541 agcaggaatc aggaataata aagtaaaaca ttacaaagga agaaaaatta gtagaaaatg
    15601 taaattagaa cttaaatcat tgactaaaat gtgggagtat gaaactaaac tgactcatga
    15661 tgcaaataag gcacataaga aaataaaatc taatatgctt gaaaaaatga cagataagaa
    15721 ttataaaaat atatatgaat atttaaataa tgagattata aatagtaatg aagaatataa
    15781 aaatatttat ttttatagct tagaattaaa gttagcgaat gaattaagaa agtgtactct
    15841 taaaaactta aataaaatta aagacataga aaatcaagta aaatttattt cttatactat
    15901 tgcttatata cacatagttc cagttttaac gataagagag aaactaagcg ataagttatt
    15961 taatatattg tcaactaatg aaggtaagga tatagaaaaa tttactaaag aagttagtct
    16021 tataatgaga attataaata tagaatgttt ggagttatta aatatagtta gtaagaacaa
    16081 ctattataaa aattttagtg aaaaggaatt agaggagttt aaatctattt ataatataaa
    16141 taatggaaga aagtcatttg aaaataaata taaaataaaa gtagattata atatagatga
    16201 tgtaagaaag tatggagagg ttataaaagc aataaatata gaaagtaaga agaaaattgt
    16261 agatagaatt aagaagaaga gaaaatctaa ttagattttc tctatttttt ttgaaaaaaa
    16321 taaaaaatat ttggtgaaaa cgtttatctt taggtgatat gagtagtcat tatttattat
    16381 ataatcatat ttgtaggaac gagctaatta ataaaatcta agaacaatag cttaatgatg
    16441 aaaaagtacg gcctttcggg ctttgacaac aggaggtata ttaatgacaa actttaaaag
    16501 tgtaaaggta gaattaattc tacttattga atgtgaagaa ggaaatcgta atgaattaga
    16561 aggtatgatt gatgaaggtg tattaaatga aaaagaatat agtttaacta tattaggtag
    16621 tacagagtat gaagataacg caagggctat ttacatactt atgaatacag gaggatcata
    16681 cgaaaaaaac ttacaacgat taagtagatt acacttgaaa attgaaaact tacttaaaga
    16741 tacaaatgtt aaatatagag gtatatcttt agtaccgaat attgttaaat gggataaata
    16801 ggaggaatac aaatgagcaa ggcaataaac agagaagaat taattaaatt atatgaggaa
    16861 ataggattaa atgttttaga taataacacc gttatgaatt catctaataa aaagatatgt
    16921 aattttttag taaatataat agaacaaagg gttatagatg gaaaaatgta tttatgtata
    16981 aatgctatgg ggattaatgg agagctatta tcagaggtaa tattagattc gaataccata
    17041 aatagaacta catgggtgat tgaaaattgg ggttttaaat attctataga taaaaaatat
    17101 attaatgact ttattgaatt gatacaacac ttatgtatga atataaaaac taagtatata
    17161 tatgaccata caggatggat atatcaagac aataagtgga tatatctaca tggaggagga
    17221 gttataggag gttcagatgt tcaagttgag ttagatgaat caatagataa ctatatacta
    17281 ccagataaaa ttagtgacat aaataaagca tgtgaaatga gtttaaagct agtagactta
    17341 atagaagatg ataaaggtat tatattctct tcattagttt acctatctcc acttattgaa
    17401 attatcagta gaaaaattaa accaccggaa aatatagtat ggacatatgg aaaaacagga
    17461 tcaagaaaaa cagcagtatc aaaagttgta ttaagtcatt ttggtgattt taataaaaaa
    17521 attccagcta catttaatga tacgattaca gctattgaat taaaagctaa taagttaaag
    17581 gatagcttat acttatgtga tgactttgca cctaaacaag actttaggga taaaaaaatt
    17641 caagactcaa aggcagaatc cattataaga atgtatggag atagagtagg gaaaggacgc
    17701 tcaagtaata agttagatat aaaggatgct aagagaccta gaggaatgat attaataaca
    17761 ggtgaagatg tgatatgtgg agaatcatct aatgctagat tattatcaat agaattaaat
    17821 agaagttcag tagatttaaa tatactaact gaattacaga ataatagtca tttgcttgga
    17881 gaagcaatga gaggatatat agaatggtta ttatctgaaa tgggaaatat tgatgaatta
    17941 tctaatatat tattatataa ctttaaatct tacagggatg aaattagaga acaatataaa
    18001 gatgatatac atggaagaac tattgagtct agtgcatgga tattagtagg ttttagttgt
    18061 atgttaaatt atattagaga taaaggtgtt atagataagt atgaagatga tgagtacatg
    18121 gatagagcga ttaaagttgt agaaagatta atagaagagc agataaaatt aatatcgaga
    18181 aactcaccta tagatatatt tttaaataca ttaaaggaat caataaattc aaagtcaata
    18241 agaatagcaa cattaaatga ccagaaccaa gttatagaag ataaattaga atatatatgt
    18301 ggatataagg ataaggaata ttattacttt tacacagata aagtatattc ttttatagaa
    18361 tttgaaaata aaaaaagagg tatacatttg ggaataagtc aaagacaact agtgaaacag
    18421 ttaagagata gtggaattgt gaaagttgat tctaacaatg attctcctaa aaaaactatt
    18481 catacaaaag atgctagcga ttcaacagga tatacaacaa taagaccaag aatgcttcag
    18541 atagaaagaa gtataattga gaactttcaa atataactta taatcaagag tgcttatgta
    18601 ctcttgatta tattctatga taaatggagg atataaatat gacagaaact tataaaatca
    18661 gcataggaag aaaagattta tattctaaag actataaggt agttgaaaga actgactatg
    18721 aaaagagaca cacagttaat ataagtagaa gcttagtaga catactttct atacttgtaa
    18781 aagaagatag atagattaaa atatggttac acacttagtg ttagtgtgta gcctttaata
    18841 tagattaaaa ttagtatatt taaactttgg aggaaataat atgacaggaa agaaagcagt
    18901 agtatatgca cgctttagtt cagataatca aagggacgaa tcaatagatg ctcaattaag
    18961 agcaataaat gaatatgcag ataagaataa tataaaaata gttaatcaat ttatagacag
    19021 agcaaaatca gcaacatcag ataaaaggcc agagtttcaa aatatgatta aattctgtga
    19081 agcagataca acaggaatat ctatggtaat agttcataag ctagatagat tttctagaga
    19141 taagtatgat tcagctatgt acaaacagaa attaaaagta aaaggaataa gagttgtaag
    19201 tgtattagag aacttagata attcgcctga atccctaata ttagaatcag ttatagaggg
    19261 aatggcacaa tattacagtg ctaatttagc gagggaagtt gctaaaggtc agaaagaaaa
    19321 tgcccttaaa gcccttcata atggaggcga tgcaccatta ggttatgatg tagcacatga
    19381 taaaacatat acagttaatg aagaagaagc tcaagcagta aagattatat ttgatagata
    19441 tattaaagga tattcatata gtaagataat agatgaacta aatatcttag gatataagac
    19501 taaaagaggt aataaatttg gtaagaatag cttacatgga atattaaata atgagaaata
    19561 tacaggagta tatgtattta ataagactca gagaaaaggt gtagatggaa aaagaaatgg
    19621 acataagcaa aagagtgaag aggaaataat aaaaatagaa ggtggtatgc cacaaataat
    19681 agacaaagga gtatttaaac aagcacaaga tatgattcaa aaaagaaaga aaactccagg
    19741 tgcacataaa gctactacta catatctatt aacaggacta attaaatgtg gtgaatgtgg
    19801 acatgcattt caggggaata agagaaaaga ttcttatgga aatgaatatg tttcatatag
    19861 atgtggatgt agaaagcaaa agagagaatg taataataga gagataaaaa gagactattt
    19921 agaagagttt atattacaag aacttgaaaa gaacatatta aatgatgaag ctataccgat
    19981 tttaagtaaa gcattgaatg agaagctgaa tgataagaat gaaagtaatg cagagctact
    20041 taaaaatcta gagcagaaac tagataaggt aaataaagag ataagtaata tactaaatgc
    20101 tataatgaat ggtatagtaa atagcatgtt aaaagataag cttgatgagc tagaacaagt
    20161 aaagttcaac ttagatttaa aaatgaatga actaaagata gaaaataaag ttgtagatgg
    20221 tgtaggtgta acagaagatc aaataagagg tatgttttca agatttaagg aatttgtact
    20281 agagagaaat atacctgaat gtaagaagtt tataggagac tatataaagg aagtaatcgt
    20341 atataaagac cacattgaag tcatattcaa tgtggtcttt tgttttgttg acaatgatat
    20401 aactcatgat ttacatatta tcacagaaag gggtaaaatt acatagtaaa tatatatttt
    20461 ataaaagtaa atatcagata ttatttagat aaaaattatt tttgaaaata ttagttttaa
    20521 aaaatatatt tatataatta taaaataaaa tggtataata aaactttaaa tatgataaag
    20581 aggtgagact attggcagat atatttacag tactaaatta tcaaggtagt aaaaagagat
    20641 tattagattt tatatatgaa aatacacaag aatatattga ttctgataaa gcttttttag
    20701 atatatgctc aggaacgagt gcagtagctt ataatatgaa aagacacttt acggtttata
    20761 caaatgatag tgaaaattat gcatatcaga tatctaattc aattgttaag aataatgaaa
    20821 gatataactt tagtcaatca gatgaaatga tcataagaga aaaatataat attaatttac
    20881 aaagattaaa taatattttt aacgatatgg taaatcagga agatatgtta ttagaacaag
    20941 aagatgcaga cggtttaata gagctatatt caaattgccc atgtatatgg aaaaataatg
    21001 ttgatattga aatagaaggc aatacaatac agagtatata tgatttaaga aaatgtaaac
    21061 gagacatacc gaatgtgtta ttcacattgt attattcaag tagttacttc ggcataaagc
    21121 agtctatgga gatagattct attagatatg ctattgaatt tatagaaagt gaaataacaa
    21181 agagcattct ttttacaagt ttatttttcg caatgaaaga gtgtgttttt gctaaagatg
    21241 gtcacatggc acagccatta aatatggaaa caggcaagaa aagaatgtta agattaaaag
    21301 caagaagtat atatgacata tttatagata aattaaagga atttaatact gaggagtttg
    21361 tattatcaca aaaggagaat aagtgcttca ataaagactt tagaacatta ttagaaacag
    21421 aagaaagtat aaaagatgaa gttggtttta tatatataga ccctccgtat acagatatgc
    21481 aatactcaag atattatcat attcttaata cagttgtttt gtatgattac ccagaaatat
    21541 cattgagtag aggaactata tcaaaaggga tatatagaga aggtagatat caatcacctc
    21601 ttagtcaaag aaaacatgca ttaaatgaga ttgatttctt atttagtttc tgtaaggaaa
    21661 ataaaataaa tgtagcatta agttatgcat atccaataga tacagaaaaa caagcaacta
    21721 atagatatac ggctagtatt gatgatttga taaatgtagc caaaaaacat tttggagata
    21781 atgttaaggt agtacatgaa gaatatagtc atgcaaataa tagaaatagt gataaaaaga
    21841 atgtacttga atatttaata atgggtatac acaataagga gtaaatatgg ataaaattaa
    21901 taaattaaaa gagaggatag ctaatataga agcgacgaat aaaaatgata tatattcttc
    21961 taacttatat tggtcacaaa aaccattcaa tatatgtgat gaaattattg aacatttaag
    22021 tgaagatgga gatataatat ttgatccgtt tatgggatct ggggttacag ttatagaggc
    22081 tttgaaaaaa gagtataaaa gaaatgctat tgggtgtgat ataaatgatg caccaatatt
    22141 tatagtaaaa acattattag aaaaatataa tgtgcctaaa atagagaaag atattaaaga
    22201 gctaaataat aaattaagta aattatcaac ttactattca acaaaatgtc gtgaatgtgg
    22261 agaagtagtt actatatcga aaactatatt cgataaggag aataggaatg caaagtgtga
    22321 gctaaagtct atacattata aatgtaagga atgtaaaaat gactttaaag gtgaaccaaa
    22381 tgaaactgaa atatctaaat tctttattga tgaagaatta aagaatatag atgattttca
    22441 attcatagcc aattcaaggc ttgcagttgg cgaaggtgat acagtaagaa ctattttttc
    22501 aaatagaaat ttaatagtat tagataaaat attaggacat atagatgaat ataaaaatag
    22561 tgaatcttat gagcctatga agtatatttt attatctatt ttacatttaa gtaagattac
    22621 agatacacat tctaattctc agtggccttt atggattcct aaaaaagact gtgttgaaaa
    22681 aaatgtagta gaattattca taaagaatag taagaaaacc attaaggcat taaaactagc
    22741 atctaaatat ttatgtgaaa atagagaaaa tgtagaacta atcaaaaatc tagatagagg
    22801 gaaatttaaa ttgataaaag atggagttca aaatatagaa gatgatgtta tacctaatga
    22861 atttgtggac ttgataataa cagatccacc atatatggga caagttttat attcagagta
    22921 tatgcagtta tataaacctt ttatggattt ggaattcgaa ttagaaaatg aaatagttat
    22981 atcaagtgcc ccagctagag ataaagggaa agtattatat tttgatatga tgaattctgc
    23041 atttgaaaat atatctagag tattaaaggt aggtaaatat atgtgtatgt acttccatga
    23101 tagtaatcta gatgtatggg ataatataat agatataatg accaataata atttgaaata
    23161 catgggacaa attcatgtaa gtaagaataa aaacactctt aaaaacatac ttagtcctaa
    23221 gaagtcgtta aatggagatt gtataatttt ctttaagaaa gatttaaata taaactatga
    23281 tataaatgaa gtagataata tagaagataa gataaataat attgcacaag ctattataga
    23341 tataaaagga tacgcatcaa ctccagagtt atatgataat ggagcactag agtatataat
    23401 atcaaacgga aaactaaaag agatttctaa aaagtataag gatttaacaa gtatatttga
    23461 gcaaagattt aattgggata aggaaagagg ggtatggact gtataataaa taaaaagcat
    23521 ctatagataa ttatagatgc tttttattta tattttatag taaactaaat atttaataat
    23581 ttctaatttt tatacaatat gttaaaggat tggctatcca aagatattat ttaatataat
    23641 tttttagcat taactctagt taaatcactt ttagataatg aaacctgtaa tcttctgata
    23701 ggagaaccct tttctaaaca tctattgatc ttttcctgta acttcttacg aagaagagga
    23761 actacatctg ctggttcagt tgagtagata tgttcaactt ctatattttc tttatcaaca
    23821 actgctaata ttatagcttt atcattataa tatttattta gtacattatc agatatatct
    23881 tgaaagttcc aagcatgatt tttagaaact ttatattcat aaggattacc ttcactatca
    23941 taggcatcat gagcaccttc tcgtccacct tgctctgggt ttacttgatg gtttaattct
    24001 aatgcaacta ttaattccca aaacttatta cttgtaagta aatttttaac tcctgttaat
    24061 tcttcaagtt cacttgaagc tttataaata gcacttagat atttatcata aacaccattt
    24121 tgagctgatg ggattatctt acttgcattt aatctagact ctagttgatt agggctgaca
    24181 tttatcattt ttctggaatt ttgtatactt tgagtatact ttagtaaata ttcacacatt
    24241 atatctccag gtatagagta ataccaatca agctttccag ggtaaggaaa atcaacatca
    24301 tttatatgag caaatataac tgccttagct ttctttaatt ttgctatact tgtatccgaa
    24361 aaatcattaa acgtccaaga atggttagag ctacttttct tgaaatgttt atattcaaac
    24421 tcatttccga attcatcttt tgcatctcta gaaccactat gtccaggtat tagtatgtga
    24481 ttaagtgaat tagcagtcat aacttcatat attttgctat tagaaagtat atcatttact
    24541 ttatattctt taaaaatacc atcttgtata gcctttagtt catttatttt ctgtgttatt
    24601 aaaacatttg ttatattatc tcttatcata ttatcatagc tccttaataa attagtattt
    24661 ttagataagt catttttaat tagatttatc acataactat tgatgctatc atttttaaat
    24721 gctactaaat ccaataaatc tttatgaaaa tcatccttga gtcttatagt tagttttttc
    24781 aagctatcac ctcggatatt aattagatgt gccgtcgaga taagtataat taagcaggtt
    24841 tataaagtca aggattaaaa aaattaaatt atagatatat aaaagtatat atagcaatat
    24901 agataaatag ctaaactatt aatcgtgggt attattcttg cgattcgtct ccaccaattt
    24961 tgaaaaaaga atgatgaaat acttggaaat actagtcttt gttgactagt attttttatt
    25021 ttggagaaga aatccaccaa ccgtacccca accacagaaa atgaggtttt tttgggggta
    25081 tattggggtg catttaggct gtataaaaag tttttatttg tttattattt tatttgttta
    25141 ttattttatt tgtttattat gataataggt aacatagaat tttaatatct actttatgat
    25201 ataatatttt tataaatgta agacagttta agttgttaat tagtaaaaat atatattata
    25261 taagcttgat aggagttgag gtttgtaatg gatgaaagaa aactagaatt ttctattttt
    25321 tgcattgaag ctttagcaga aaaattgaat atagattcag aaggagttta taaacttctt
    25381 aaacatgata ctgatatttt agataactat ataatacctt gctatgaagc actacattct
    25441 caaagtaaag gttacatagt ggaagattta atgcaagtac ttaaagaaaa gggtgtgata
    25501 taatgattgt atatcatggt tcatattgtg tggtaaagac gcctagtatt accttttcaa
    25561 gagattcttt agattttgga aaaggattct atgtaaccag tataaagaca caagcaatta
    25621 actggacaga gcgttttaaa aaaagaggta aaaaagcata tttaaatagt tattctttag
    25681 atattgataa attaaaagaa aactgcaagg taaaaatctt cgatagttat aatttagaat
    25741 ggcttgattt tataatagaa tgtagaaata tgagtgatat atatatgaaa tatgacatta
    25801 taataggtgg tattgctgat gataagattt acaatacaat agaactgtat caagataatc
    25861 ttattgaaaa agatgaagct ttaaaaagat taaaatacta taaaccaaat gaacaaatat
    25921 gtataaccaa tcaaaatgta atagataaat atttaaagtt taggtatgaa gaggaggtat
    25981 aatgattatg gaagcaaata aaacattatt acaaatacta tataaaaaaa tcatattaga
    26041 attttccaaa caaacaggta agagcttgga agaaagtatg gattatttat atacttctga
    26101 aacatataaa cttataagtg agggtgtatc agatatgcac tgtaagggtc atatatactt
    26161 ggctcaagaa ttaatgttag aaaatggatt aatgtaccat aagggctatc caagataaat
    26221 aattaaaact agatacgaaa taaggataca atataatata aaattaattt gtatccttat
    26281 tttgattttg taattaacta tatgaaatca caatatttat atgtatttga tttttacaat
    26341 gaaaatattt tatccaactt ttctacagct tcaactttct tatcttccat aacttgagta
    26401 tatatattca aagttattga tatatcataa tgacccatta aaacttgtac agttttagga
    26461 ggaacatcat tctcaaaaag tctagtagca taagttttcc taagaccatg aaactttata
    26521 ggctctatat ttaagctatt taatatagac tttaaattcc ttaaaggtct tttatcatct
    26581 atagggatgc ctaattcatt gcaaaataca taattattat ttatatataa ttctccagcc
    26641 tttaatatat ctgtattttg atttacttta tgctctttca atttatttaa aacatctttt
    26701 ggaataggta cagttctgta agaatttgat gtctttggcc cttgctctaa tactttaagc
    26761 tctctatttc cagttttatc tataaaatat gttctttgaa gagttctttt aactgttaaa
    26821 ttagactttt taaaatcaat atcaaaccat ttaagtccta ataattctcc taatctaagt
    26881 ccagtaccaa gagcaagtaa aaataatacc tctaatttat gcccatctat agcttttata
    26941 aaactctttt gttgttcaag agtcaatatt tcaagtttgt tttctttttt ctcaactggt
    27001 atatttacca tagtacaata gttacgttgt ataagacctt gtttttcagc ttctgataag
    27061 caggttttca gtttagtgtt tatttgcctt atagtaggta tacttttatt ggaatcaagc
    27121 aatctattgt aatatttttg tatgtgagat actcttaagt actttaattt aacattgcct
    27181 aaatcagtat ctttaatata attacgatag atgctttcat atctttcaaa tgacttgggt
    27241 tttaaatctt ttattctata ttcaaataac caattgtaaa accaatgctc taaagttatt
    27301 ttatcatctg aaatatcaga gcttaaataa tattgttttt tataagcatc taatttatct
    27361 ttaacttcct tttgagtctt accataaaat tcttttctca gtggtttacc atcttcatta
    27421 tagccaatca ttatacggga acgccaacca tctttatatt ttccgataga gccttctcca
    27481 ttagctcttt tagttgccat ttttaaacag ctccttatat gatttatagt tatatccatc
    27541 aaagaatgta atacatttct ctaataagaa ttttataact tcatcagctt ctagtgtttc
    27601 atagaagttt agcattaatg tgttgtactc ttgtttatgt ttagctggta ttgatagaac
    27661 tcctatatca ttatttataa gtattaggtt tgaggtaagt ctagcagttc ttttgttgcc
    27721 atcatagaag aattggcaat aggacaacca taaatttatt attatagcct tttctaatgg
    27781 gttagttatt ttatttatga tatttatgtc atttacaaat aaatcattta atagagtggc
    27841 ttctatgcat tcatattgag tagtaccagc tatacctata ttaccatttc tgaaatctcc
    27901 aacgattaga gcttcatctt ttgcaactat tttatgtata gagcaaattg tatctttatt
    27961 taaagataag ttttctttgt tacttaattt tattacataa tcccatgatg attttatatt
    28021 tagtatttga ttttggtcac ttaatttatg tccgcctacg gttataccat caagtaatgt
    28081 ttgtacttct gggaatgtga aggggttatt ttctaggtta cccatatcat atacaaattc
    28141 acttatcatt cttctaatgt atgttaaagt atatttttta tctccatgag gtatattagt
    28201 agggaattta tgtgtgtatt ttggtatata tgatttattc atgattttag ctcctttcat
    28261 atctaatttt tatttattaa ctatgaatgt ataaaagtta ataggtaaac tcatattttg
    28321 aaaatgtgca atactaatat tcttcatcct catcttcaat aagaccatta gagttttctt
    28381 gtataaaatt ttcaacaaga ccatttatca cccaatttag atttttggag aagtctttga
    28441 agtcagagaa gtttaggtta attggtttta ttgtatctgc attatctgta atttcaaact
    28501 tttttttata gtctgttttt atatcataac cataattttc taatatgtga attactaaat
    28561 ccaactcttt atcaaatact tttaaattaa tattattatt tgttaaagta tctaaatcat
    28621 tttcttcaac aatgagttta tttatagcaa ttgataaagc agtagctatt tttcttatca
    28681 tatctaaact aggcattctt tgattttgct catatttagc tatagcatga actgaacaac
    28741 caatcttgtt ggctagctca tcccttgaca tatttatcga ttttctatat tgtttaatct
    28801 tttctccaat tgtattattc atcataattt caccttaaat atatcatcaa acaatgattg
    28861 tacttctaaa catgtaaagg agttattttc tagattatcc catatcatat actaaattac
    28921 tcataactct cttagtgtat gttagagtat attttttatc tccatgaaat aaattagtag
    28981 gggatttata tgtgtatttt agcatatatg atttattcat aattgtaact ccattcatag
    29041 ttttttatca ttgctttaga tagtattgat attattttat attttagtta gtagtttttt
    29101 tatttcttta agtgtatttt caagcttttc atttttttcc tttagttcgt tattttcttg
    29161 taataattta aagtaatcat tatttttaat agtaatattt tctttttgag atattaattt
    29221 ttttagtcga atattacttc cattatctgt tgagtcacta aagtaatcat agattgtttc
    29281 tatactttct tctgatagac caatatctaa taattcatca attgattgtt ttgtaagaac
    29341 atcattttta ataatttctt ttatgtcatc aggatgtaat gaaaaatcta attcagtatt
    29401 agatatacaa tctgaaagta tccaattata aacttgattt tcatttagtt ctaatttttc
    29461 accaagttta taatattggt ctttatcaga ccaggcacct agcaataaac ttgaggtaat
    29521 tctaatatca tcttccataa gatttgaaat agcatttaaa aattcatcaa aagaatagta
    29581 ttcttctggg aataaagact gtaaaaggta taaaacatct tcattagtca ttacttcatt
    29641 ttcaatatca aaataaaaga tagtcttttc aattttcaaa gctttagcga gttttgataa
    29701 ggtatctata ctaggtattc ttttatcatt ttcataattt attagagcat ttcttgagat
    29761 gccactaatt tcagcaagtt gaatctgcgt tagctctttt tgttttctta tcttttttaa
    29821 gttttttcca atttgcaata ttatcacctc gtataaagta tatcccaaaa gtacacaaat
    29881 gagaacagaa aaataatata ttcttattaa cagtacacat atatcgacat tataattaaa
    29941 atgtaaagtt tacgaatgta aactagaaaa aaggaggaaa aagtatggga atcaatttaa
    30001 aaatatttag gattaaaaaa ggtctaaagc aacaagaact ggcagataga gttggtatat
    30061 caagatatta tttatcaaac ttggaaacag gtaaggctaa taatccaagc aatgatttga
    30121 tgattaaact atctagagct ttagatacaa cagtagaaga attatttttt agtaaggagg
    30181 attaaaatat gaaagagaat aataatttag aggttttaaa gacattacaa gccactttaa
    30241 acattattgt aaagaatgaa gaagaagcac aagaaaaaaa gcaaggatat aaaattattg
    30301 aaaatgcgaa aagaaataaa gctgagctta taacatgtaa agaagcatct aagctttatc
    30361 ctataggaga atcaaaattt aggcagttat gtcattctaa aaacaaagga ttcccttgta
    30421 tatggataaa taatcgagta tacataataa aaaataaatt agatgattgg tttattgaaa
    30481 atgcaaatgg tatcaagtta tagtcttaaa gtaggtgttt gcaattgagc aataaagggt
    30541 ggataaagct ttatagggag ttgttggata aatcaatttg gaaagatatt aaaccagaaa
    30601 gaaaggtaat attaataact ctattactta tggctagtca taaagaaaat catgttttta
    30661 tagataataa aaagataaaa ataaagtttg gacaatttat ttcttcatat agcaaaatag
    30721 ctgaaagatg tggtaaagga gttagttatc aaatggttag aagttgtttg ttggttttta
    30781 aaaatgctgg ttttctaaca tacgaaacaa caaacaagta tatagtaata actattgaaa
    30841 actgggagct ttatcaagag aatatagaaa atcaacaacc taatcaacag actattaaca
    30901 atcagtcaac aacaatcaag aatataaaga atgaaaataa tattatatat agtgaaatca
    30961 taagcaaatt taactcaact tgtattgaac tttcaaaggt caagaaacta acagatacaa
    31021 gaaagaggag aataaattca agaataaaag aatatgataa agaaactgta ttagaggtta
    31081 taaatatagt tagtaaaaca agttttctga atggaaataa taatacagga tggaaagcaa
    31141 attttgattg gataatgaat tcaagtaatt ttactaagat actagaggga aattataata
    31201 gcaaggaaat tgtcataaat aaagagacag gaatatataa tccagatgac tcacaattaa
    31261 agtggtaagg aggttatatt ataaataatt caaacaactt aattaaaaat acagaagcag
    31321 agcaatcaat taaattacac taagttagtt ataaatcttt catatatttg ttttttaagt
    31381 atctctaata tcgtttaaat tacactaagt tagttgcaga tataccagaa aatatatata
    31441 aaattatgcg taaactatat tgttatgagt acaaataata tttacctatt cattaaaaaa
    31501 cttaactaag aatttaattt atattattga agtatcaata attttggaaa gtagaaaatt
    31561 ataccccaat aataccccaa ctacaaaaat agacaataaa aaataaccag aaaaattgct
    31621 tcaacatcat gaccaaatag ccatatacct atacttataa aaaccaacaa aacaatcaaa
    31681 taaccactta taaattctcc tcggtctcca ccattggaat ccacgaaaac atattgattt
    31741 aatagttaat atgtttttta ttttgaaaaa tcatatataa tataaattaa tagtttattt
    31801 aaaaatttca gtatgagcac aaaattatat aattattggg aattagttat aataagtaat
    31861 ttctagtaag aatgatttgc aaaaaataat aatttaaata caaaaaacta aaggatagaa
    31921 gtcataaaat taacttttaa cctttagtta tataaataaa aaattagtta ttactaaatt
    31981 aaaattagat ttttaaagaa cccaatatct ctattatcca tatcaccaat taacatgctt
    32041 ctatcaagta ataaattata ctcctcacag ctagtttcag gcaataaagt acatgaatgg
    32101 catgctccta gatttaaaga atttctacct tgaccagtac tatcaataca tattgggtca
    32161 ttagaacacc aaagagcacg attaagagca ctatttaata tagatggtaa tgaatcatgc
    32221 ataccttgcc taactaatcc tcctaaagta ccttcagagt caccacttgc agtgtaaact
    32281 aaaattccag acataacttt ttcattttcg gaattattac aatatatacg ttccctaagt
    32341 gaagaggtag catatccaca aacaaaacta agttctctta taattaaatg agctaaagta
    32401 tgtagtaata agaatttagg tgtaattttt ctataagctt tgtcattaac attaatatct
    32461 ttattatatc tagaatttaa aatagatgca ttatcctgta ttttaggatt agatgaaatc
    32521 cagcttttta ccatatcatt atttatctct atgaaaatac cttcacctct aacctcagat
    32581 gcaggataaa aagatttttt acaatctcta gatcttaaac ttataacctt agtatcatta
    32641 cagctatcat ctatatcttc ttcaccaaat atattattat caggtggatt gactctacta
    32701 aacccagtta atgcccttac ttctctaagt ctttttacta acactatttt actgaagttt
    32761 ggaatatcat aatcagatag attttgttct tctattgtaa agtcattagt ttttttagat
    32821 ttagcatcta tatttccaat taaagcctca tattcttctt ctctatattg atttctagtt
    32881 gttgttgatg gtgaagaatc ttcaaaaggc aataaatctt tcaaaactat ggatacttta
    32941 tcagtatcaa aacctgtttc tttagcaata tcactggcaa agtcctcaaa atcctcatcc
    33001 ataaagcgtt ctaacttatt ctttttaata gcacgatcta agaatttctt aaatgtatca
    33061 taacctttac tagatagcac tttagaatta agagtatcag agtatggtgg tataataatt
    33121 gaactttcta tcttaggata atatacatta gaggcacctc tttgagaagc aaatgaatat
    33181 ttagtgcatt tatttacttt tttattatac caaggcgaat taccagagca tttaaacatt
    33241 tccttatatt cactaggtac accataatca ttagatttag aagattttaa acgcataaat
    33301 gcgcccttca tattagcttt agctccacag ctacattcaa gttctatacc ttctaatcct
    33361 aggttacttt ttccagtctt cattaatatt tgaggatttt cacaaatttc ttttcttcca
    33421 gatttatttc taaaatgaac ccattttacc catggaaaat catcaatatg accatgttca
    33481 caaatagtaa ttataccagt aggtactaat tgtttagtag acttttttgt gctacaagta
    33541 aggcaaatag gtattttcat aggtttatct ttatgagcat ttttataaag tttctcccaa
    33601 tcttctatag gcataaattt tctacatttt ggacaaaagt accatctagg aaacctaaca
    33661 aaaggaacag aagatctatc atctatagtt ggaggtgttc ttagttcatt aaccctcaat
    33721 gtagcctgaa gcctatcatc ttgtatttta attgtattag tccaataatt tggatgagca
    33781 gtcattaatg tttgatcaat aaaatctagc atagctcctg gtccaaaaac acttgtagct
    33841 tgatttattc ttaaattatg agttttatca tctaatttta tagacatatt aattttcctc
    33901 caattctata atttcaacag tacattgttt atcaacattt ctcatagaat ttaatgtttg
    33961 tttttcattt gtaataacat ccttatcata aggaattaaa agattattat atattttatt
    34021 atcaaattta ctagggcgct tataataatg caataaatta tctttatcag atatttgagc
    34081 tttatcatgc cataaatcca ttataatatc taattcagat gaaatctcag atttaaattc
    34141 atttactata ttatcatcag cattttgatt attttctcta aatatatcga tagatctatc
    34201 tattatgaag ttttttaaat cttctacacc atccatattt tttgaaaatc gacttgcaag
    34261 atcattagct tgaagtccta aaatatgtct aatcatactt attaatactg catgcatgcc
    34321 tctttctcta gctggttcag agaaaggtgt aatactagta ggttcaacaa atttatagaa
    34381 tgattgatga taactaaaga actgttcata atgagatcta tctcttgttt ttgtaggatt
    34441 atataatgta aatataagtc cttcattact tctaccaact ctactgctag cttgtatgta
    34501 ttcagatgtt aacttaggct gaccaactac taccattaaa tttaatctat caacatcaac
    34561 accaactgaa atcatattac tagctaatag agtatcgaca gttaaattat tagaagtaag
    34621 agtattagat agttcatcta aagttgtatt tatcttagta gaagtaagtc tactagtaag
    34681 ctctctttgt tcatttaggt tccttaatga ttgataaggg tgggctgaga ctcttttaca
    34741 taatctttcc atgttgtctt ttatatcgtc atttaaaagt gtgctacact tacctaattc
    34801 tctgatacta ttaaaataag atactagtgt ccaatattta tccaataaat tcaactctac
    34861 attctccatc attttaagtc tttggagtaa tgctgacata agtctaacct ctacagtaac
    34921 ttgagttttt ccagatggaa taacacctac atatagtcgg ccacgttttt tacttaaagg
    34981 catctcttta acaaagaaag agttactaga tgttaatcct ggaggtggaa actgagctac
    35041 attacgatta tatagatttt taacttgatt ttgtgctttt cttatagtag cagtagaagc
    35101 tataatctta ggttttatac ccttatagct acacatagca tcaagtgcag tttcatataa
    35161 acctaccata gtacctaaag gtccagaaat aagatgaagc tcatcttgaa ttattaactc
    35221 aggagataag ttgctattat catcatctaa agcaaaaaga ctagctactt ctgtagtcca
    35281 agttatcatt gcaaatttat caactgtacc aaataaaagt gttggagggt tattataaat
    35341 ctcctcatct acaacttgta taggtaacat atcttcaaat gaacaatctt cttcaggaca
    35401 gcataagtag aatttcttag gtctagattt aattctatag ccccaatcac caacagcttt
    35461 tttagaagtt ttatcccatt ctttaacaag ttttgttcca caccaaggac attttagtaa
    35521 ttggaattta ttatattttg attttaaatt atctaactca tattcactat ttatactaga
    35581 tctaaactta atgttattac ctgttaagtt attaagcatt tcttctgcct catcattaaa
    35641 gtttggagtt tgatcactcc caatccacaa accaatagaa atctcttttt tcccaagttc
    35701 agacttattt tcttttctaa taatttcaca ggcacaaatt aatatacttg ctcttatgaa
    35761 ttgttgtgca gccaatagcc ttagtgtata tctcattatg atagctgtac cgttaccatt
    35821 ttctttgttt cttattcttc ttaagaagat agtaaaagca gatagaccta agtaggcctc
    35881 cgttttacct ccaccagtag ggatccaaag aaggtcaact aaatctctat gtttagagtc
    35941 aggattttct atcgaagata aacatgtaag tatataagca agctggaatg gtctccaagc
    36001 agaattatca tttgagtaat ctatatagtc aaggttatta gatccaggga gtctatccgt
    36061 aatatgtata gaatgacatc tttgcataag tatagctcta ttcattagag aaaatgctct
    36121 gtatacttca tcattagact taattaaatt tataccttct agcattctag acttagtatc
    36181 tctgcagttt tttatatgct catatgctac atctttaaaa acatcactaa gatcttttga
    36241 atcttcttct agatcatcta tccaaatatc ataagcatca acaaacttat aaagaaaata
    36301 tattttctta tctttactaa gatcagagat atctgataaa tttttcatag acagtaattc
    36361 tctagaaaca tcacttaatt catctacatt aaagtccaat ttaggtactt caaaatgagg
    36421 aataaactca gtacaaagtt ttattaaagc atcattttga atatcttgat ctatagctac
    36481 accatgacca gtagcaaaag tttttttatt tcggtaaagt aagtctaaag atatttcctc
    36541 agaatctaac tttttaaaag tatttactga tccagctgta aaaatatcta taaactctaa
    36601 atcattgtta tcttcagcta ataccattag ttcaggctgg aaaatagtat tattatattt
    36661 cttaggccca gattgactat taaccagcat acaagtaata ctaacaaagt catttgaata
    36721 aattctttta gataaaacta tatctaaatc tttagatata ggttttttaa tatagttttt
    36781 atccatatct attgatacta ttaagttttc atgtggaaca cgaacataac caccagtctt
    36841 attctcatca tcagggcatt ggttagctaa cttgtataaa acaaatttag cttcagcatt
    36901 atcaagtaaa tcatgctttt ttagtaaatt ataaaccttc tcagatgtta gtttttgctt
    36961 aagatatagg aatgatcccc taagttctac atattcatta attgtattgc tagaatagaa
    37021 gtcgtcacca gtatatttaa catgacagtc tgtatataaa gcatttctat aagtagcata
    37081 atttaccctg aaatttatta cttctgcatc tttttttagg aaaaaagtca tacccataga
    37141 agaaggtaaa gtttcattag acatacttat agctctatct agttcatttt gtgtatcatc
    37201 tgatgtaaat acattatctt caccatcata ttcagatgta ttacttacat caatattgtt
    37261 attaagtgga tataaaatac ctgttgaata acgctctatt ggactatctg ttattatttc
    37321 atattttata ttttcacaaa gatcttccga accaggtcca agaagttctt ttcttacaag
    37381 atctagggtt ttatctctta gttcactaca attcatattt acctcctatt tatttaataa
    37441 acactatata agtctaaaac tttgttaaca aggtggggtg acagatactt atcacaactg
    37501 tgtatttctc gtatttgtac aggtgtaaca taatcatttg tattcccaag catacttaaa
    37561 acaactgcag acacttcatc tttaattata tctgatttac tgctaaagaa attatcagat
    37621 acaaatgtat ctatagattt ttttatttta gtgtgcaaag agcgtatact tttagtagca
    37681 tcatatacct cggtatgatc taatttagaa tctataactt taaatatctt ttcgaaagtt
    37741 tttaaatata taggacctat taatctttta tttgttaccc agtttttgat tgttatagga
    37801 ttaatctttt cacctaaaac agctaaactg tttgatacat cattataatt atatttacta
    37861 taagatatat agtttttaag ttctgatttc catgaattag ttaatttata atcatcaaga
    37921 taatgagatg gcaataaatt aagttctaat agcttttgta taacattaat aactaattca
    37981 ccctcttcat ttaagtaatc atcaacaaat aaaaaccagt cattaacttt agcctctgaa
    38041 agtttctttt tcctaacact ttttttatcc caatctattg aataggctat tgcctttttt
    38101 gtacagaata tatactcatt attatcagaa atcatgaatg atgtaacatg ttctttttta
    38161 gagttgtaaa tcccttgatt tatagataga gataatataa tttcatttaa atttatatca
    38221 aatttataat tagatatata ttcatccata gaatcatcat cagaaatagg actatcggta
    38281 gaataagctt ctaatttatt ggtttcataa gttggtttaa aaggttttat atcaagtaag
    38341 ttatatattt tattattttt ttcaatttta tttcttgcag aatttatttg attcatatag
    38401 taattatatt tggataattc act
//
LOCUS       DAEPHU010000038        38271 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 01A10CD0081
            SAMN05941466-rid12468953.denovo.038, whole genome shotgun sequence.
ACCESSION   DAEPHU010000038 DAEPHU010000000
VERSION     DAEPHU010000038.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941466
            Sequence Read Archive: SRR6291087
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 38271)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 38271)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068158.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 22:43:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,892
            CDSs (total)                      :: 3,805
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 87
            rRNAs                             :: 8, 1, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 55
            CDSs (without protein)            :: 55
            Pseudo Genes (ambiguous residues) :: 0 of 55
            Pseudo Genes (frameshifted)       :: 21 of 55
            Pseudo Genes (incomplete)         :: 28 of 55
            Pseudo Genes (internal stop)      :: 16 of 55
            Pseudo Genes (multiple problems)  :: 8 of 55
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..38271
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941466-rid12468953.denovo.038"
                     /strain="01A10CD0081"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            <1..606
                     /locus_tag="KR231_002011"
     CDS             <1..606
                     /locus_tag="KR231_002011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HBH0004383.1"
                     /translation="ISGYLTKKLQDLNVDTIRTDILTSPTVTDVIVWNIEQSGTDTFS
                     ATYEVDQQIKEGEQTTTVKATYTVKVHVDADRDMVIIQNPTLAPAIEKSDYEPKTPEA
                     DASVDADTVNDATAFLETFFKLYPTATAKELAYYVFGNVLEPIGRDYLYSELVNPVLT
                     KDGDNMKVKVAVKFLDNQTKATQVLQYELILHKDSNWKIIM"
     gene            819..1676
                     /locus_tag="KR231_002012"
     CDS             819..1676
                     /locus_tag="KR231_002012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002585362.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HBH0004384.1"
                     /translation="MYKEVGISSNNVPITLSIWYTERSSPTIVFLPGTMSHPLMYENF
                     LCGLSERGFNIIGIHYLSHGKSPKIKKNYTMEDLLHNVYDATTYGIENFGENIAVMGS
                     SQGGILAAMAAGRDTRLKAVFPHNIMLTTLKETMSLTKYPTWSHRFMGLIQWGFRVGG
                     KLLPNYKVPGDAYLDYDRVFYSEQAKQDCLNDPMLLPYYPLRFVTSLFNADLSCLENG
                     AIQCPVILITAKGDPLFSFDYTNKVFDLIHVPQKELLALELNRHMIFNEDTDTTINAL
                     EATLHKYLG"
     gene            1754..2335
                     /locus_tag="KR231_002013"
     CDS             1754..2335
                     /locus_tag="KR231_002013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBH0004385.1"
                     /translation="MPRFTEQEKEIINSKLLIEGEKLFALHGLKKVTVDDLVAAVNIS
                     KGSFYAFYPSKEHLYVEINFRLQKELFTSIETTIKKKKYKNHRDLAKDVIMLSLTGVI
                     TSPILSQIDLSLMDYLQRKISSDIFENHMYSDIRILEILEDLGVVFLVPHTVIIKSLY
                     SVLSCLEQFKEDEELNMIQNLLVNGIIQQVVAE"
     gene            2439..3284
                     /locus_tag="KR231_002014"
     CDS             2439..3284
                     /locus_tag="KR231_002014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH0004386.1"
                     /translation="MIDVKKLYFSYTDKPFVENVSFHVGRGEIFGFLGPSGAGKSTIQ
                     KVLTGLNTRYKGSVKVAGTEIREHTNQFYENIGVDFEFSTCYEKFTARQNLAYFASLY
                     EKQPRSIDELLHMVGLENDGDKKVADFSKGMRSRLNFIKALVHDPDILFLDEPTSGLD
                     PTNSRLMKDIILAEKKRGKTIIITTHNMFDATELCDQVAFIVAGKVSALDSPHNLIMS
                     RGAAKIQYTYYDKGEKTGECLLDRTTEDKLLKSLISENRLLSIHSSEPTLNDIFVDIT
                     GRTLQ"
     gene            3281..3964
                     /locus_tag="KR231_002015"
     CDS             3281..3964
                     /locus_tag="KR231_002015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016295773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBH0004387.1"
                     /translation="MRLGRLICGDIHFQWKYGFYFIYFILTVLYVCGIAALPEHWKTD
                     IASIMIYSDPAAMGLFFMGAIVLLEKSQKVLNAMVVSPVKISEYILSKTVALIAISTV
                     IALILGVVSGSNHLLGIAVGTALTSAIFTMLGIIAATKISNLNQFLIVIMPIEIICFV
                     PPIVGLFVKLPYLFRFFPFTACMNLITGKSVLLSFDMVLVIATLIILYIVARHTVEHM
                     WKSLGGVKL"
     gene            3961..4659
                     /locus_tag="KR231_002016"
     CDS             3961..4659
                     /locus_tag="KR231_002016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002583502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBH0004388.1"
                     /translation="MKKILSSTIQIFKQIKSDPMMFAACFSPFIMGTLIKFGIPFLER
                     ITKFSLQAYYPIFDLLLSIMAPVLLCFAFAMITLEEIDDKVSRYFSITPLGKSGYLFT
                     RLGVPSIISAVIAFIVLLLFSLEKLSIGMTICLALLGSVQAIIVSLMIITLSSNKLEG
                     MAVTKLAALTLLGIPAPFFIDSYYQFAVGFLPSFWVAKAMQNEAVLYFSIGLVVALVW
                     YYFLTKRLFRKLAG"
     gene            4671..5582
                     /locus_tag="KR231_002017"
     CDS             4671..5582
                     /locus_tag="KR231_002017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation transporter"
                     /protein_id="HBH0004389.1"
                     /translation="MEKGRLLQNKNMNKAIQVSKITLIINLSLSLLKFAAGYIGKSSA
                     MLSDAVHSASDVVSTIVVMVGIKISEKQPDREHPYGHERMECVASIILSVALAITGAG
                     IGYSGIKKIFSGQYNTLSVPSGIALTAAVLSIVIKEWMYWFTRSAAKHTNSDALMADA
                     WHHRSDALSSVGSLIGILGARLGYAILDPIASVVICGCILKAALNIFKESINKMVDHS
                     CDNATETRIREVVLQQQGVDGIDELKTRMFGAKMYVDIEILADGNLALYDAHRIAEGV
                     HQTIENNFPQCKHCMVHVNTNELLYSA"
     gene            5634..5774
                     /locus_tag="KR231_002018"
     CDS             5634..5774
                     /locus_tag="KR231_002018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016295776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0004390.1"
                     /translation="MEQYWWIIIVVVLIVVGLLKIVIMKKYNQRRNSNNRSKDSEDDK
                     MY"
     gene            6065..6691
                     /locus_tag="KR231_002019"
     CDS             6065..6691
                     /locus_tag="KR231_002019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBH0004391.1"
                     /translation="MSDTKENILKIALHLFAVNGYEAVSVSMIAEALGMTKGALYKHY
                     KNKQDIFDCIVERMYQIDNKRAKDYQVPESTIEVTPNAYRNTTIGSLITFTLAQYDFW
                     VTDEFASNFRKMLILEQYRNLKMNMLYQKCLVNGPISYIEDIFNEMIEKGVLQECDTK
                     QLAIEYYAPLFLLISVADAVENCWDLKTQLTTHVKQFVKKYIINEKVK"
     gene            6813..7529
                     /locus_tag="KR231_002020"
     CDS             6813..7529
                     /locus_tag="KR231_002020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HBH0004392.1"
                     /translation="MEYIRSKKYFTPDLQTKIMGPNPIKLQEELLQNHKIPSGSYVCD
                     LGSGQGLTSVFLAKEYGFVVFAVDLWSEPKENEEFFKKMGLSSAQIKSVKADANELKF
                     EKEFFDAVVSTDSYNYFGRDPIYLDEKLLPFVKKGGFVYITVPGMKKDCHEKLPEELL
                     LSWTPEELDYIHDITYWSNIISHCKKADLISIYEMESNSEVWSDWIKQNNEYAINDRK
                     AIEAGGGDYLNFIAIILQKK"
     gene            7679..8275
                     /locus_tag="KR231_002021"
     CDS             7679..8275
                     /locus_tag="KR231_002021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015541496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF998 domain-containing protein"
                     /protein_id="HBH0004393.1"
                     /translation="MKILWIIIIMADNLLPLLLARFYPNYKHKEMALSVLGSRQSPVK
                     WIYNVWCIISGVVFCIAPYALYQENDSGWAIAIWMLLAIYGIGCEIISGVCPLNENRQ
                     DEDIITKIHGGTSAIGFMALLVVPLLFAILQFQTTKVVLGAISLVCFTIAFIFFCFFI
                     MGEKEKFANTVLRYGGLWQRLVLISCYIPLFVWSVSNQ"
     gene            8362..8553
                     /locus_tag="KR231_002022"
     CDS             8362..8553
                     /locus_tag="KR231_002022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003064779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4177 domain-containing protein"
                     /protein_id="HBH0004394.1"
                     /translation="MKKYEYVEINYNAKGVVFLCTDKHKEIIDSYAKTGYHYAGFVPT
                     EIDAKGCMRKIDLIFEKED"
     gene            8577..8807
                     /locus_tag="KR231_002023"
     CDS             8577..8807
                     /locus_tag="KR231_002023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0004395.1"
                     /translation="MIGLKRRDMNYIMKVGAKAQGVSVSEFRAMLQDTIDKTMESTDP
                     DVQANFKRYFGNKRPTPEEYIYTITKKTKVKV"
     gene            9074..9493
                     /locus_tag="KR231_002024"
     CDS             9074..9493
                     /locus_tag="KR231_002024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009261829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HBH0004396.1"
                     /translation="MKPSDFQKTIQCQFECKLKKVVKGIIWNYRKELKRRKNKEISFS
                     ELPDITVESLATWDDYETNYTIFNVCGIDIKVLDDELAEALKQLPEKKRNNVLMYYFL
                     EMSDTEIADIMNYTRGAVFKHRHRALETMKEILKEKK"
     gene            9496..9750
                     /locus_tag="KR231_002025"
     CDS             9496..9750
                     /locus_tag="KR231_002025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBH0004397.1"
                     /translation="MKKKYKHPSYYLISSAMDGDETAIEKLLAFYDPYISKCCLRPLY
                     DEYGNVYIVVDMELKGRIREALIKMILDFEIDIDIETEEE"
     gene            10125..10328
                     /locus_tag="KR231_002026"
     CDS             10125..10328
                     /locus_tag="KR231_002026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excisionase"
                     /protein_id="HBH0004398.1"
                     /translation="MNNTDVPIWEKYTLSIEEASRYFRIGEKKLRKLAEENLDSGWVI
                     VNGNRIQIKRKQFEKIIDTLDEI"
     gene            10406..11596
                     /locus_tag="KR231_002027"
     CDS             10406..11596
                     /locus_tag="KR231_002027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006354938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HBH0004399.1"
                     /translation="MSKMKRQDSKGRNLRLGESQRKDGRYVYKYTDIFGKPQFVYAWK
                     LVPTDKTPTGKRDDKSLREKEKQIKKDLDDGIDTIGGKMTVCQLYAKKNNQKKNIKRN
                     TEIGRQYLMNALENDPLGMRAIDTVKQSDAKEWAIRMNDKGYSYKTIDNYKRSLKASF
                     YMAIQDDCIRKNPFHFKLSDVLEDDTEPKVILTPEQEEKLLSFMETDNVYSKYRDEVI
                     LLLETGLRISELCGLTTHIDMLNRVINIDHQLLRDTEVGYYISTPKTKNGKRELPLTE
                     RAYQALERILKNRGKAQPLVVDGYSNFLFLNREGLPKVAGNYESMVRGLIKKYNKTHE
                     DKLPNITPHSFRHTYCTNMANKGMNPNTLQYIMGHANITMTLGYYAHGTFQSAKAELE
                     RLAS"
     gene            complement(11853..12653)
                     /locus_tag="KR231_002028"
     CDS             complement(11853..12653)
                     /locus_tag="KR231_002028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBH0004400.1"
                     /translation="MRLNKRSEGYINYVKGVKREKRNVLFYQLLILIGFIVIWELLAD
                     LNVINTFLFSKPSDIYNLFIQYAFSGQLFKHIGISVYETVLGLVIGTVLGILVAIALW
                     WSEKLSKILDPFLVVLNALPKTALAPIIIVWVGAGIEGIVVTAVTISVVVTILSAYNY
                     FMNIDEEKIKMLKSFGATKSQILFKLILPANTGNLINLTKINIGMAWVGVIVGEFLVS
                     RYGIGYLIVYGSQVFKLDLVMMGVFVLAICAWAMYAVVNIIEKIYNSR"
     gene            complement(12848..14446)
                     /locus_tag="KR231_002029"
     CDS             complement(12848..14446)
                     /locus_tag="KR231_002029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HBH0004401.1"
                     /translation="MKAAIYSRKSRFTGKGDSIENQIQLCIDYAKSIGVKDFLIYEDE
                     GFSGSNIDRPQFKKMMQDAKDKKFSYLVCYRLDRISRNVSDFSTLIEKLNELSISFIS
                     IKEQFDTSTPMGRAMMFISSVFAQLERETIAERIKDNMYELARSGRWLGGNTPHGFNS
                     EKITFLDENLKERSMYKLQVNDEQMEIVKLIYNKYLELRSLSKLYKYVYNNGIRGPRG
                     GKFDPSSLSRILRNPAYVKANDEILDYLKNSGMDVVGTPDRKCGILTYAKNTSNSIAA
                     IAKHHGVIEPEIWLEVQNQLDKNRDKTPRISTGKTALLSGLIKCGKCGSNMRITYKGK
                     KTDKDLKYYYICGTKKTLGSDSCNCKNLNGPLVESLVIDKIKNCKEESIISAFNSNNI
                     KTDNVFNIFKSETNLLKNQILDKERLIKNLVIELAKNTGSTASDYIVSQIESLNNEIS
                     ILKDKINILESSNINISSDSINIDIIVSNLKRFNDEVDNASLDDKRLLLSTIINSIVW
                     DSSLGNLNIVYMGAEVDNSVSLSN"
     gene            14774..14950
                     /locus_tag="KR231_002030"
     CDS             14774..14950
                     /locus_tag="KR231_002030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0004402.1"
                     /translation="MEINVIEIFPKDKAKLNKIEMDKASWFVNIISKKYPKEALNEAF
                     STLEKELNISKANT"
     gene            15124..16254
                     /locus_tag="KR231_002031"
     CDS             15124..16254
                     /locus_tag="KR231_002031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003462216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase"
                     /protein_id="HBH0004403.1"
                     /translation="MNNFEIKTRIKFGEGSLKALQELKNKNVLIITDPFMVKSKTIDK
                     ITSNLINSTYQVFEEIVPDPPIEVVVAGIEAFKSINPDVIIALGGGSAIDAAKSIMDF
                     SKKILKINEVEFIAIPTTSGTGSEVTSFAVITDSQKKCKYPLVSDDLLPDMAILDPEL
                     VKTVPNFITADTGMDVLTHAIEAYVSTNSNDFSDALAEKAIKLVFKYLIKAYKDGNDI
                     EAREKMHNASCLAGMAFNQASLGINHSIAHVLGGKFHIPHGRTNSILLPHVIEYNSSI
                     VGYTNTTYSATAKKYAQIAELVGLGSANIRISVRNLVNEIKKLQKEMNMPTKLTQCKL
                     SLEDITNEEREIAKLAIKDTCTLTNPKVPTEDDIINILKNIK"
     gene            16495..16845
                     /locus_tag="KR231_002032"
     CDS             16495..16845
                     /locus_tag="KR231_002032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003453843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BMC domain-containing protein"
                     /protein_id="HBH0004404.1"
                     /translation="MTEESKQRVIQEYVPGKQVTLAHIIANPNEDIYKKLGLVLDKKD
                     AIGILTITPSEASIIAADVATKASNVSLGFIDRFSGSVVISGDVSSVESALNDVLEVL
                     GNMLNFSSTKITRT"
     gene            16853..17302
                     /locus_tag="KR231_002033"
     CDS             16853..17302
                     /locus_tag="KR231_002033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EutP/PduV family microcompartment system
                     protein"
                     /protein_id="HBH0004405.1"
                     /translation="MKNIIFMGKTGSGKTTLCQKLDQLELKYKKTQSVELYNNAIDTP
                     GEYMENRNLYNALITTSADAKIIAIVYDATQEENYIAPGFASMFCKDVIGIITKINKA
                     TENEVNIAYERLSLAGASQIFKIDTVDNIGLEKLFKYLEKYKNIDEV"
     gene            17404..17979
                     /locus_tag="KR231_002034"
     CDS             17404..17979
                     /locus_tag="KR231_002034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HBH0004406.1"
                     /translation="MGKKILLVDDEPLLRMDTKDILESHGYEIIGEASDGFEAVEMCK
                     KHKPDLVIMDIEMPILDGIKAGKIICKENIAGGVLLLTSFEDKEYVEKAKSIGAYGYL
                     VKTASEKSLIPTIEMCLNKVNEFEKMKKDLEKVNSKLNERKLVERAKGILIREFKISE
                     DEAYTRIRKLSMDKRTTMMEIAKMIIIGYDD"
     gene            17972..19381
                     /locus_tag="KR231_002035"
     CDS             17972..19381
                     /locus_tag="KR231_002035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine kinase N-terminal domain-containing
                     protein"
                     /protein_id="HBH0004407.1"
                     /translation="MTNTIKKISTAQTYLNNNEIEKIIEVSKSLDLMASFYEADVFID
                     VLSKFDDEAIVVAHGRPKEKSMYCENVIGKKALIENEPGVIKCLKTGERVRDIKALTQ
                     EYKLVKQNIQPITLDDKVLAVLIVEKDISSEVKNEFNASEDEENKNLHQFIKLIGNND
                     FLVDNLNSAILIFDKNGKLKIKNRIATEIYKNLGFGYDIQDMHYNDLDIETNTFENIL
                     MDENYDETNEVSIGNMFFKIKTIYIKDDEFKVCKIVQDISDLKRKEEELVLKTVAIRE
                     AHHRVKNNLHTVISIIKKQSRLSQNDEVKQCLDNIINRVFAILSTHYLLSKEVDNNIS
                     IREGINLLVSNIQGGYLFSKDIDIRITGEDFKISGEKATAILLVINEILQNCYDHAFS
                     DREHGTIQILINKDNDYRNIAIIDDGIGFDSNNINKNSLGTYIIDSYITQMLKGNIER
                     KSSENGTEVLITIPTQINI"
     gene            19565..20998
                     /gene="eutA"
                     /locus_tag="KR231_002036"
     CDS             19565..20998
                     /gene="eutA"
                     /locus_tag="KR231_002036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004458698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ethanolamine ammonia-lyase reactivating factor
                     EutA"
                     /protein_id="HBH0004408.1"
                     /translation="MREELLSVGIDIGTSTTQLIFSKLIVENTESNFSVPRISIVDKE
                     IIYKSKVYFTPLISNNEINGQQIKDIVENEYKKANISKEDIHTGAVIITGETARKENA
                     NDVLHTLSGFAGDFVVATAGPDLESIISGKGAGAHIYSKEHSTTIVNIDIGGGTSNIA
                     SFKRGEVTDTGCLDIGGRLVKIDKISKKITYISPKIDKIIKDNNLNLQVGTMATVENT
                     KPIVDIMVDLLMESIGLKKQTPLFDFIITNKSISIDENIKNVSFSGGVADYIYYDGEI
                     KDYFEYGDLGILLGQAIKNCEYLKKVNVVKSMETIRATVVGAGSHTTEVSGSTITYTS
                     EKFPLKNLPVLKLSIDEETGTSKQISEAIKNKLNWFKLENDLQKVAIAMIGKKNPTFL
                     DIQEYAKGFVDGMQQIIENDLPFIVIVENDMAKVLGQAIYALLNYEKEIVCIDSVKVE
                     NGDYIDIGKPIVEGKVLPVVIKTLVFN"
     gene            21016..22380
                     /locus_tag="KR231_002037"
     CDS             21016..22380
                     /locus_tag="KR231_002037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003454054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ethanolamine ammonia-lyase subunit EutB"
                     /protein_id="HBH0004409.1"
                     /translation="MILNTKLFGRTYQFKGLYDVMAKANEEKSGDKLAGLAAESAEER
                     IAAKVVLSHIKLEDIRNNPAVAYEEDEVTRIIQDAVNEKVYEEIKNWTVSELREWLLD
                     SNTTSLDIRRISRGLTSEMIAAVAKLMSNMDLVYAAKKIKVTAHCNTTIGEQGTLSAR
                     LQPNHPTDDPDGILASLLEGLTFGIGDAVLGLNPVDDSVESVTKVLKRFEEVKQKYQI
                     PTQTCVLAHVTTQMEAIRNGAPADLIFQSIAGSEKGNEAFGFNGDTIEEARQLALKHG
                     TATGPNVMYFETGQGSELSSEAHHGIDQVTMEARCYGFAKKYEPFLVNTVVGFIGPEY
                     LYDAREVVRAGLEDHFMGKLHGLPMGVDVCYTNHMKADQNDMENLAILLTTAGCTYFM
                     GIPHGDDVMLNYQTTGYHETASLREMFGLTAIKEFDAWMEKMGFSKDGKLTELAGDAS
                     VLLG"
     gene            22393..23274
                     /gene="eutC"
                     /locus_tag="KR231_002038"
     CDS             22393..23274
                     /gene="eutC"
                     /locus_tag="KR231_002038"
                     /EC_number="4.3.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014952556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ethanolamine ammonia-lyase subunit EutC"
                     /protein_id="HBH0004410.1"
                     /translation="MNEKDLKALVEQLVGQMLGELDTNVVSETVKKATEVVVDNNACI
                     DDITEVDIRKQLLVKNPKDAEAYLDMKAKTPARLGIGRAGTRYKTETVLRFRADHAAA
                     QDAVFSYVDEEFIKENNMFAVETLCKDKDEYLTRPDLGRKFSPETINNIKSKFGTNQK
                     VLILVGDGLSSAAIEANLKDCVPAIKQGLKMYGIDSSEILFVKHCRVGAMDHLGEELG
                     CEVICMLVGERPGLVTAESMSAYIAYKPYIGMAEAKRTVISNIHKGGTTAVEAGAHIA
                     ELIKTMLDKKASGIDLK"
     gene            23294..23947
                     /gene="eutL"
                     /locus_tag="KR231_002039"
     CDS             23294..23947
                     /gene="eutL"
                     /locus_tag="KR231_002039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003761789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ethanolamine utilization microcompartment
                     protein EutL"
                     /protein_id="HBH0004411.1"
                     /translation="MKNDVIRPNILGIKIISNISPEMAQKLELKSHHKSLGLITADCD
                     DVTYTALDEATKASEVDVVYAKSMYAGAANASTKLAGEVLGIIAGPSPAEVRSGLNAV
                     VDFLEYGATFISANDDDSIAYYAHCVSRTGTYLSEVAGIREGEALAYLVAPPLEAMYA
                     LDAAMKAADVKMCELFAPPTETNFGGALLTGSQSACKAACDAFAEAVKSVADNPTGF"
     gene            23958..24659
                     /locus_tag="KR231_002040"
     CDS             23958..24659
                     /locus_tag="KR231_002040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BMC domain-containing protein"
                     /protein_id="HBH0004412.1"
                     /translation="MDAIGLIEVIGYVAAIEASDACLKSANVNIVRVDKVGAGIVTLT
                     ICGDVGAVKAALEAGEIAASRVGTLRTSHIIPRIHNEVTNALFKTKEPKVCEVSEDKE
                     KNFEITLEIADNVSKNLSEKENVILDVNENSGDTENLYSDIDKTNKKIETVDDSLTEA
                     NEEKIENTNDKEVLEQVKIENSDFDRDDLSKNSVKKLKAMAKKLDSSITYKDLNVLKK
                     EELINLVKKLSRRDR"
     gene            24662..26131
                     /locus_tag="KR231_002041"
     CDS             24662..26131
                     /locus_tag="KR231_002041"
                     /EC_number="1.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetaldehyde dehydrogenase (acetylating)"
                     /protein_id="HBH0004413.1"
                     /translation="MTLLDKDLVSIQEVRTLVRRSKVAQEKLSKMSQEQIDKIVKAVV
                     DAAFNNATKLAKMANEETGFGKWEDKVIKNTFASMGVYETLKNTKTIGIIGEDKEANT
                     IDIATPVGVVAGLIPSTNPTSTVIYKTIISLKAGNTIVFSPHPNAKNCILETVNIISE
                     AAIKAGAPEDSILCITNPSIVGTNELMKHKDTNLILATGGEAMVRAAYSSGTPAIGVG
                     PGNGPAFIDKSANVKLAIKRIIDSKTFDNGVICASEQSIVIEKSMEETVLKELKNQGA
                     YVLNEEESERLAKFILRANGTMNPQIVGKSVEVIANLADLTNVPKNTKVLVARENKVG
                     HNVAYSREKLTPILAFYVEENVEAIMNRCREILLNEGAGHTFSMHVNDEELVKRFALN
                     MPVSRILVNTPSALGGIGASTNLVPALTLGCGAIGGSSTSNNIGPLDLINVKRVAYGI
                     KEIEELGRDKSQVEKSMFDSMDKEELINLLVQKLVKELA"
     gene            26227..26514
                     /locus_tag="KR231_002042"
     CDS             26227..26514
                     /locus_tag="KR231_002042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_464705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BMC domain-containing protein"
                     /protein_id="HBH0004414.1"
                     /translation="MASANALGMIETKGLVGAIEAADAMVKAANVQLVGKEQVGGGLV
                     TVMVRGDVGAVKAATDAGATAAERVGELISVHVIPRPHFEVDAILPKVSAE"
     gene            26641..27402
                     /locus_tag="KR231_002043"
     CDS             26641..27402
                     /locus_tag="KR231_002043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalamin adenosyltransferase"
                     /protein_id="HBH0004415.1"
                     /translation="MGVLTENEVKRKIGKNKNNITEFYIEKGQIITPSAKSYLAERSI
                     ELKYVDKLSDVNNEPKEVVKEVVKEKKYKYTTVFGAKLDEKPEHMTQLNGNLLVFKDH
                     KRIILRGKIDSLESEILKVQILCQKLDMPKLVKELQEVLDFVRNIMRCEVLDEKLGDF
                     KLLGLTPQELREQSHYPKKYFGIGHEFPSYEMGEVVVAINSIRSNTREVELAAYEAFK
                     GEYGNVHREDLIKALNRLSSVFWIMIYKVRTNKYK"
     gene            27415..28044
                     /locus_tag="KR231_002044"
     CDS             27415..28044
                     /locus_tag="KR231_002044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate propanoyltransferase"
                     /protein_id="HBH0004416.1"
                     /translation="MENLLNEIVEEVITRVKKEAFIEVEASGRHVHLSREDVDKLFGE
                     GYTLTKLKDLSQPGQYACKERVTITGPKGSIKNVVVLGPCRNETQVEISLTDGSTLGL
                     KAPIKQSGDLEGTLSIKISTQYGEVELDKGLMVAKRHIHMTPKDAEKFNVCDKEIVEA
                     KVMGQRPLTFDDVVIRVSDSFKTYMHIDYDEANACGYSKGTVAKIIKKA"
     gene            28086..28811
                     /locus_tag="KR231_002045"
     CDS             28086..28811
                     /locus_tag="KR231_002045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR02536 family ethanolamine utilization
                     protein"
                     /protein_id="HBH0004417.1"
                     /translation="MNYDNLVDLITEEIYKKINSNEIKISNKPKAVIVFEQDNNKFNL
                     LKDGFEIVEFDKSIRECEIVIVSRLCMRGLSNIALGNSTSDEERFILKMIMNGKKVYV
                     LDEGIEYKKYKDTAPKALYKKFMSFEDEICKFGVEIIKDLNVITKNKLNIKKELESTR
                     GSKKEDTKVLDKDILNLTSVESVKIDNEFSLDLRNKKLISEADLRKPTINGVKNILVN
                     KKSIITPLAVDFMRIHHLKLKKL"
     gene            28824..29096
                     /locus_tag="KR231_002046"
     CDS             28824..29096
                     /locus_tag="KR231_002046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EutN/CcmL family microcompartment protein"
                     /protein_id="HBH0004418.1"
                     /translation="MDIGKVVGNVWATRKDEKLCGQKLLVVKILKTKDTYKEGFMVAA
                     DNAGAGNGDLVLISKGSSARESIEKSHVPVDATIVGVVDSFEVFDE"
     gene            29089..29640
                     /locus_tag="KR231_002047"
     CDS             29089..29640
                     /locus_tag="KR231_002047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729042.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BMC domain-containing protein"
                     /protein_id="HBH0004419.1"
                     /translation="MNKSIGAIEFKSIAKGIEVSNEMIKKSSVDVLYLKSICPGKFLI
                     IVGGETSYINECVDYGIKLGEGYIVDNFVINAISQEILDGFKNKYQKLDSIVSIGVVE
                     SSKICAGIKMLDKTLKSGDLVLVKLQLSFAIGGKLVYIVAGDLSSLEYALKESENVVR
                     EKEVIYKTVIPSVDSQIIKSLIK"
     gene            29652..30743
                     /gene="eutH"
                     /locus_tag="KR231_002048"
     CDS             29652..30743
                     /gene="eutH"
                     /locus_tag="KR231_002048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ethanolamine utilization protein EutH"
                     /protein_id="HBH0004420.1"
                     /translation="MSINEIIIYVMVVFMVLGAIDKCIGNKFGLGEQFEEGIMAMGSL
                     AVAMVGVICLAPVLADVLRPIVVPVFNILGADPAMFAGSLLANDMGGAPLALELAKDP
                     NAGLFGGLIVGAMMGPTIVFIIPVALGIIEKEDQKFLATGILAGIITIPIGAFVGGLV
                     AGFEVMMVLRNLVPIIIFAVVIALGLLKFENAMIKGFTYFGKGVVIVITLGLAAAIVE
                     ALTGIVVIPGMKPISEGIEIVGDIAIVLAGAFPLVFVITKVFNKPLMALGKVLGMNDV
                     SAAGLVASLANCIPMFGMMKDMDNRGKIINVAFSVSAAFVFGDHLGFTAGFNSNMITP
                     MIVAKLVGGITAVLLAMVIANKTLKKENV"
     gene            30745..31218
                     /locus_tag="KR231_002049"
     CDS             30745..31218
                     /locus_tag="KR231_002049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893336.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF861 domain-containing protein"
                     /protein_id="HBH0004421.1"
                     /translation="MDISNIDKNLIETLVRQIIEEKISGTKDTVDFVRNKDISGITSI
                     KLPTVKVSESDRLDTGNPSDVVYTKDLFTLEESPRLGCGMMEMKETTFDWTLNYDEID
                     YVIDGTLDIIIDGRKVSASSGELIFIPKGSKIQFSVPDYARFIYVTYPADWASQN"
     gene            31731..32252
                     /locus_tag="KR231_002050"
     CDS             31731..32252
                     /locus_tag="KR231_002050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HBH0004422.1"
                     /translation="MEEIVKKEQASMNDIFLYLKAKSNSLYKFVILYNEFINKPKDYG
                     TGELINMVEVHMLTAIEENPGISPTQLAKIWNRTKGAISQTISKLEKKGYITKEKKEG
                     NAKTILLYPTTSGVELSKAHKLYDTIDVTRTFEYLIKECTLEEIDSFYKVIDLFINLL
                     EESPQENNDSEKV"
     gene            32631..33794
                     /locus_tag="KR231_002051"
     CDS             32631..33794
                     /locus_tag="KR231_002051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HBH0004423.1"
                     /translation="MNLKQLSEKYEEYVIQMRREFHKYPELSFKEIRTTQRIREELQK
                     IGVPFVSIEPNIVIATIQGKNEGKTIAIRGDIDALPMQEDSDVEYKSEYDGIMHSCGH
                     DAHGAMLLGLAHMLNDIRKDLKGRVLLVFQAAEEVGGGHKEIIQYFKENGGPDRLIAT
                     HVWSDIEAGKISVEPGPRMAGGSGWRIDITGRGGPDQSIDPIKPACDIVLKVSSIPVN
                     HISVLEQCVVHACAIHGGTTIGNVIPNNAEVIGGYRYFTEESGKKVFDIIKQMSNGVG
                     QVYGVDVKVTHTGGIGPVINDEEAVKMAKEIVSNIDGLELDSYEPICASDCYGEILKE
                     YSGFYCYLGVGNKEKGIIYAQHHPKYNIDEDILKLGCEFMAKYAVEFLNKNNN"
     gene            33828..35366
                     /locus_tag="KR231_002052"
     CDS             33828..35366
                     /locus_tag="KR231_002052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbgT family transporter"
                     /protein_id="HBH0004424.1"
                     /translation="MQGALKENKKKSGGGFLGWIEKVGNKMPHPLALFTYITLIVVAL
                     SAIASFLGFSATSPATGKLIKVMNLISAKGLVLFMQEFVKNFQNFPVLGVVLVMAVAT
                     GVCEKTGFFSTAIKMSLSKVKGNAVVFIIAFIGVFANQAGDAAFVLVPTLAGAIFYGL
                     NRNPLAGIFCGFASVGGGFATAVIPGGWDVTLTPITVSAAQTIQPAFDMTLLASYYAL
                     FVSAFIVATVSTIVTVKFIEPKLGKYTGKPEGIDDNQGFEVTKEQAKAAKLAGFTVLA
                     YVALLIALCIPANSFLRSPEGSLIFGAPLMSCLQFFIVILFFLPGIVYGMRVGKIKTV
                     KDLNDILCQSMAAMAPFIVLAIVIGQFLTLFSVSNLAQVLAIKGGALLNSLPLPPQAI
                     ILLFLVLVAFINIFVISGSTKWMIFGPVFVPMLMQLNIHPAFTQFVYRLGDSVTNHLS
                     PLNAFFIILLATVQKYDKNAGMGTIFSAMIPYTIGYFVVLAVLVVVWMTIGIPVGIGG
                     QVWL"
     gene            35398..36600
                     /locus_tag="KR231_002053"
     CDS             35398..36600
                     /locus_tag="KR231_002053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HBH0004425.1"
                     /translation="METTEIRYNFDEVIDRSGTNCLKYDLKSQFMPESPEDALPLWVA
                     DMDFACAPEIINAMHERIDRKIFGYSSQQTDDYYEAVCGWFKRRFDWKIEKENIFFSP
                     GVVPALGFFTQILTQKGDGIIIEKPVYYPFEDKITNNERKVVNSPLKFEDGHYSMDYD
                     GFEELAKDENNKVFILCSPHNPVGRVWKKEELRKIVDICKKYDLWIISDEIHCDIIRK
                     GEKHIPLEVACPDYKDRIITCTAPSKSFNLAGMQLSNIVINNKELQEKWMLETDSKLA
                     IFLPNPFAIVATKVAYNDCEDWMNQVNEYIDGNIKYVEDFVNEYMPKVKIIKSQGTYL
                     VWLDFRGYGLDAKQLEYVMLNKAKVLLDEGYIFGEEGAGFERINVASPRTIIEECMNR
                     IKCAFEGL"
     gene            complement(36767..37366)
                     /locus_tag="KR231_002054"
     CDS             complement(36767..37366)
                     /locus_tag="KR231_002054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBH0004426.1"
                     /translation="MNDNIVEVKNINMNFYTKEGELEVLKDVNFNLKEGEILTLLGPS
                     GSGKSTILNILTNLLKPTSGDIKITGNIGYMFQKDNLLEWRNIMDNITIGLEIQGKKD
                     KKSLDRVESLLKTYGLWDFRSMYPKELSGGMRQRVALIRTLSVNPDILLLDEPFSALD
                     YQTRLLVCDDVYSIIKNENKSTILVTHDIGEARCIKVQL"
     gene            37536..>38271
                     /locus_tag="KR231_002055"
     CDS             37536..>38271
                     /locus_tag="KR231_002055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0004427.1"
                     /translation="MSNIITNLIESIFTNPITILFLLAITVYSVFKIIENNRVYSFVS
                     SKLDEINRDYKTSEFYKKVRDDYYTYSKENPYADVNITSFIEEVVSDLKHNNLPLLEK
                     IRSIKNSSSISILLGVLGTFVGLSTMLLCVDTKDIINSLPSTISSMQTAFTTSIFGVV
                     FSLIIGYFTKIKDCEHVLIQIMLKSENLLTSEITHFKSERMDLKVEEVKNTIKQISKS
                     IEAIEKFDKISKDLNDFNDEFISGIEA"
BASE COUNT        14467 a         5061 c         7000 g        11743 t
ORIGIN      
        1 atcagcggtt atctaacaaa gaaattgcag gacttgaatg ttgatactat tagaaccgat
       61 atactgacta gccccacagt tacagatgta attgtgtgga atatcgaaca gtcgggaacg
      121 gacacttttt ctgctaccta cgaagtagat cagcagataa aagagggaga acagacaaca
      181 acagtcaagg caacctatac ggtaaaagtc catgtagacg ctgacaggga tatggtaatt
      241 attcagaacc ctacccttgc accagcaatc gaaaaatcgg actatgagcc aaagacacca
      301 gaagcagacg caagtgtaga cgctgatacc gtgaatgacg ctaccgcatt tctggaaaca
      361 ttctttaagc tgtacccgac agccacagca aaagagcttg cctattatgt atttggaaat
      421 gtgcttgaac ctatcggcag ggactacctt tattcagaat tggtaaaccc agtacttaca
      481 aaggacgggg ataatatgaa agtcaaggta gctgtaaaat tccttgataa tcagacaaag
      541 gcgacgcagg tattgcagta tgagcttatt ctacataagg atagtaactg gaaaattatt
      601 atgtaagaca ttttgttggc aggatctatt ttcggatata gtctgccttt tctgtagcaa
      661 atgtactgca ctgacaagct atttcattgt attttaagca attaaacctt tcttgacaat
      721 tttatcttaa atcatatatt tatggatatt gactttctgc ttgcaataag ctataatatg
      781 actataaaat caaatcagtc atataggagg tatgtggtat gtataaagaa gttggtattt
      841 cttcaaataa tgttccgata acactttcta tctggtatac agaaagaagt agtcctacca
      901 ttgttttttt gccgggtact atgtcacacc ctctcatgta tgagaatttt ctatgtggtt
      961 tgagtgaaag aggatttaat ataataggca ttcactatct ttcacacgga aaaagcccta
     1021 aaatcaaaaa aaattataca atggaagatt tgctgcataa tgtatatgac gcaacaactt
     1081 acggaataga aaatttcggt gaaaacatag ctgtcatggg ttccagtcaa ggcgggattt
     1141 tagctgcaat ggcggcaggt agggacacaa ggttaaaagc cgtttttcca cataatatca
     1201 tgctgaccac attaaaagaa actatgagct taacaaaata tcccacatgg tcgcaccgtt
     1261 ttatggggct gatacagtgg ggctttcgtg taggtggaaa attgctgcct aactacaagg
     1321 ttccaggaga cgcttattta gactatgaca gagtatttta tagtgaacag gcaaaacaag
     1381 attgcttaaa tgaccctatg cttttaccct attatccttt aagatttgtc accagcttat
     1441 ttaatgctga cttatcgtgc ctggagaatg gggctataca atgtcctgtt attttaatta
     1501 ctgccaaagg cgacccgctt tttagctttg attataccaa caaagtattt gatttaattc
     1561 atgtaccgca aaaggaatta cttgctttag agcttaatcg tcacatgatt tttaatgagg
     1621 acacggacac tacaataaac gcattggaag ctaccttgca taaatatctt ggatagcata
     1681 ttgattatat aatcagtaaa tgttatactt ttcatgacga tataaatatt ttagtcataa
     1741 ggaggttatg agtttgccac gatttacgga acaagaaaaa gaaatcataa acagtaaact
     1801 tttgatagag ggagaaaagc tgtttgcatt acacggctta aaaaaagtaa cagttgatga
     1861 tttagtagct gctgtaaaca tatcaaaagg ttctttctat gctttttatc ccagtaaaga
     1921 acatctatat gttgaaatca attttcgctt acaaaaagag ttatttacaa gtatagaaac
     1981 aaccattaaa aagaaaaagt ataagaacca tagagattta gcaaaggacg ttatcatgct
     2041 aagtttaacg ggggtgatta cttcgcctat tctttcacag attgatttat ctttaatgga
     2101 ctatctgcaa agaaaaatat cgtcagatat ttttgaaaat catatgtaca gtgatattcg
     2161 tatattggag atattggaag atttaggggt tgtatttttg gttccgcata cggttattat
     2221 aaaatccctg tattctgtct tatcctgttt ggaacaattc aaagaggacg aagaactgaa
     2281 tatgatacaa aatcttttag tgaatggtat tattcagcaa gtagtagcag agtaacaatt
     2341 ttgtttggtt atttgacagg caggtagcca aacaaatttt ttacagttta tatgactata
     2401 tatctataaa cgtcataaag ttaaaggagg aatgaataat gattgatgta aaaaaactgt
     2461 attttagcta tactgacaaa ccgtttgtgg agaatgtaag tttccatgtt gggagaggag
     2521 aaatttttgg ttttttagga ccctctggtg ctggaaaatc aactattcaa aaagttttaa
     2581 ctgggcttaa tacaagatat aaaggcagtg taaaagttgc aggtacagaa ataagggagc
     2641 atacaaatca gttttatgaa aatattgggg tagactttga attttcaacc tgctacgaga
     2701 aattcacagc acgacaaaat ctcgcctatt ttgcttctct atatgaaaag caacctcggt
     2761 ctattgatga attattgcat atggtaggct tggaaaatga cggggacaaa aaagttgctg
     2821 acttttccaa aggtatgcgt tctcgcttga atttcattaa agcgttagtc catgaccctg
     2881 atatattatt ccttgatgaa cctacaagcg gtcttgaccc tacaaatagt cgtttaatga
     2941 aagatattat tcttgcggaa aagaaacgcg gaaaaacgat tatcattact actcacaata
     3001 tgtttgacgc aacagagcta tgtgaccaag tagcctttat cgttgccgga aaagtcagtg
     3061 cattggatag cccgcataat ttgattatgt caaggggagc tgccaaaata caatatacct
     3121 actatgataa aggcgagaaa accggagaat gtctgcttga tagaaccaca gaagataagt
     3181 tgttaaaaag tttaatttcc gaaaaccgtt tgctttctat tcatagtagt gagcctacat
     3241 taaatgatat ttttgttgat attacaggga ggacacttca atgagattgg gacgtttaat
     3301 ttgtggtgat atacatttcc aatggaaata tggtttctat tttatctact ttatattaac
     3361 agttttatat gtgtgcggga ttgccgcttt gccggaacat tggaaaacgg atattgcttc
     3421 tattatgatc tactctgacc cggcagcaat gggattattt tttatgggag cgattgtcct
     3481 cttagaaaaa agtcaaaagg tgttaaatgc tatggtggta tcccctgtaa aaatatcgga
     3541 atatatactt tcaaaaacag ttgcgttgat tgctatttct acggtaatcg cattgatatt
     3601 aggggtagtt tccggcagca atcatttact gggtatcgca gttggtacgg ctttgacctc
     3661 agcaatcttt actatgcttg gaattattgc agctacaaaa atttcaaact tgaaccaatt
     3721 tctcattgtg attatgccga tagaaattat ttgctttgta ccacctattg ttggtctgtt
     3781 tgtgaagtta ccatatctgt tccgcttttt tccattcaca gcttgcatga accttataac
     3841 tggaaaaagt gttttactat cgtttgatat ggtacttgta attgctacgt tgattatcct
     3901 ctacatagtt gctcgacata cagttgagca tatgtggaaa agtttgggag gtgtaaagct
     3961 atgaaaaaga tattatccag caccatacag atatttaagc aaatcaaaag tgaccctatg
     4021 atgtttgcgg cttgcttctc cccttttatt atggggactt taattaagtt tggtattcca
     4081 tttcttgaaa gaataacgaa gttttcttta caagcgtatt atccgatttt tgatttatta
     4141 ctttctatca tggctcctgt attgctctgc tttgcatttg caatgattac attggaggaa
     4201 atcgacgata aagtgtcacg gtacttttcg attacccctc ttggtaagtc ggggtatctc
     4261 tttacaaggt tgggagtacc ctcaattatt tcggcggtca tcgcttttat tgtactgtta
     4321 cttttttcat tagaaaagtt gtccattgga atgacaatat gtttggcgct tctcggctca
     4381 gtacaggcaa ttattgtttc acttatgatt atcacattat caagcaataa attagagggt
     4441 atggcagtta caaaactagc tgcacttaca ttgctcggaa taccagcccc cttttttatt
     4501 gatagttact accagttcgc ggttggcttc cttccatcat tttgggtagc gaaagccatg
     4561 cagaatgaag cggttcttta tttctccata ggattggtgg tagctttagt ctggtactac
     4621 ttccttacaa aacgtctgtt tcggaagctg gcaggataag gaggcatatt atggaaaaag
     4681 gtagacttct gcaaaacaaa aatatgaata aggctattca ggtttccaaa attacactaa
     4741 tcatcaatct gagtttatcg ctacttaaat ttgctgccgg atatatagga aagtcaagtg
     4801 ccatgctgtc ggacgctgta cattcggctt ctgatgtagt aagcacaatc gttgtgatgg
     4861 ttggaattaa aatatcagaa aaacagcctg atagagaaca tccttatggg catgaacgta
     4921 tggaatgtgt ggcttccatt attctctctg ttgcattggc tataacgggt gctggaatag
     4981 gatattcagg tatcaagaaa atcttttcag gacagtacaa tacgctttct gtccctagtg
     5041 gaatcgcact tacggcagca gtcttatcta ttgttataaa agagtggatg tactggttta
     5101 caagaagtgc tgcaaagcat acaaattctg acgcacttat ggctgacgca tggcaccacc
     5161 gctctgatgc actctcgtcg gttggttcct taattggcat tttaggagcg cgtttaggct
     5221 atgctattct cgatcctatt gcaagcgttg tgatttgcgg ttgtatctta aaagctgctt
     5281 tgaacatttt caaagaaagc attaacaaaa tggtagacca tagttgtgac aatgctactg
     5341 aaacaaggat tagggaagtt gtgcttcagc agcaaggggt tgatggtatt gatgaattaa
     5401 aaacccgcat gtttggagcg aaaatgtatg tagatattga aatattagct gatggtaatt
     5461 tagctcttta tgacgctcat agaattgctg agggagtcca tcaaacgatt gaaaacaact
     5521 ttccacaatg taagcattgt atggtacatg ttaatacgaa tgaacttctc tattctgcat
     5581 aggacaggga agatgattta aggctattga aagggaaagg agggaagtag gttatggaac
     5641 aatactggtg gattatcatt gttgtggttt tgattgtcgt tggcttactt aaaattgtaa
     5701 ttatgaagaa gtataaccaa aggagaaatt ctaacaatcg ttcaaaagat agcgaggacg
     5761 acaagatgta ttaaggttta ttgaaatctg ttatgttgta gaatgatgtt tttagatact
     5821 agaaagtgct ttaagggggg ctaacgttaa ggaaagcttt gagtacaatt ctttacaatc
     5881 aacagtcttt tgcatagaga aatgtatgta ggaaatatgg tgcaaggcac aaaacaccag
     5941 caattgagaa atcaacctat gaaccaaagg cacactacat tttatactac ttgacaagta
     6001 aacgaacatt tactttaatg gtttaaagaa gtaaacgttc gtttactaaa gaaggaggtt
     6061 gtaaatgtct gacacaaaag aaaatatatt aaaaattgca ctacacttat ttgcagtgaa
     6121 tggttatgag gctgtttctg ttagtatgat tgcggaagcc ttgggaatga caaaaggagc
     6181 attatataaa cattataaaa ataagcaaga tatttttgac tgtatcgtag aacgtatgta
     6241 tcaaattgat aataagcgag ctaaggatta tcaagtacca gaaagcacaa tagaggtaac
     6301 cccaaatgca tacagaaata caactattgg aagtctaata acatttactc ttgcacaata
     6361 cgatttttgg gtgactgatg aatttgcgtc taattttcgc aaaatgttaa tactagagca
     6421 atatagaaat ttaaaaatga atatgcttta tcaaaaatgt cttgtaaatg gtcctatcag
     6481 ttatatagaa gatatattta atgaaatgat tgaaaaaggt gttcttcaag agtgtgatac
     6541 aaaacagctt gctattgaat attatgcgcc attatttcta ttgataagtg tagcagacgc
     6601 agttgaaaat tgttgggatt taaaaactca attaactaca cacgttaaac aatttgtcaa
     6661 gaaatatatt ataaatgaga aagtaaaata atcctttatt ctgtcctaaa tataaaccta
     6721 actttttaat ttcagcagag aaactcaaaa tgaatattgt tataagtcac aaatattaac
     6781 tattaaaata ttacaataac ggagatgaga aaatggaata tattcgcagt aaaaaatatt
     6841 ttacacccga cttacagaca aaaattatgg ggccgaatcc tataaaatta caagaggaac
     6901 tattacaaaa tcataaaatc ccgtctggta gctatgtctg tgaccttgga agtggacaag
     6961 gtttaacttc tgtatttctt gcaaaagaat atggatttgt tgtttttgca gttgacttat
     7021 ggagtgagcc aaaagaaaat gaagaatttt tcaaaaaaat gggattatct tctgcacaaa
     7081 ttaaatctgt aaaagctgac gccaatgaac ttaaatttga gaaagagttt tttgatgctg
     7141 tagtaagtac agattcatat aattattttg gacgtgaccc tatatattta gatgaaaaat
     7201 tgcttccatt tgttaagaaa ggtgggtttg tttatatcac agttcctggc atgaagaaag
     7261 attgccatga gaaacttcca gaagagttat tgttatcatg gacaccagaa gaacttgatt
     7321 atatacatga tataacatat tggtctaaca taattagtca ttgtaaaaag gcagatttaa
     7381 tttcaatata tgaaatggaa agtaattcgg aagtttggtc ggattggata aagcaaaata
     7441 atgaatatgc aataaatgac cgtaaggcaa tagaagctgg cggtggagat tatctgaatt
     7501 ttattgctat aattctacaa aaaaaataaa ttctttagaa ccaaacacta taatttgcgt
     7561 tctaatatgt ttaccgattg acatcaataa ttttatcttt gagggtaatg atttgaaaat
     7621 agaagaatac aagaagatac gaaattgata aattagaatt tgatgggatg gtgatattat
     7681 gaaaatatta tggatcatta ttattatggc agataatctg ctgccgttac tgcttgctcg
     7741 tttctatcca aactataagc ataaagaaat ggcactatct gtccttggct ctcgtcaaag
     7801 cccggtgaaa tggatatata atgtgtggtg cattatatca ggtgtggtat tttgtatcgc
     7861 tccatatgcg ttgtatcaag agaacgatag cggatgggca atcgctatat ggatgcttct
     7921 tgctatatac ggcatcgggt gtgaaatcat ttccggagtg tgcccgttaa atgaaaatag
     7981 acaagacgaa gatataatta caaaaattca cggcggcaca tcggcaatcg gatttatggc
     8041 cttgcttgtc gttcctttgc tctttgcaat tctgcaattc caaacaacaa aagtagtgtt
     8101 aggcgcaatt tcactggtgt gctttacaat agcattcata ttcttctgct tttttattat
     8161 gggtgagaag gaaaagtttg caaatactgt tttgagatat ggcggtcttt ggcaaaggct
     8221 tgttttaata agttgttata taccgttatt tgtttggtct gtttctaatc aataaaattt
     8281 agtttatagg aataacaaat tccagtttgt aaaagtcaat aaatccaaag ataaatttgt
     8341 atttgaaagg agttttgaag aatgaaaaaa tatgagtatg tagaaattaa ctataatgcg
     8401 aaaggagttg tattcctttg tactgataaa cacaaagaaa ttattgacag ttacgcaaaa
     8461 acggggtatc actacgcagg gtttgtaccc acagaaattg acgcaaaagg ctgtatgcga
     8521 aagatagatt taatttttga aaaagaagat taacttattt tagggagttg gttctaatga
     8581 taggacttaa aagacgagat atgaattata ttatgaaagt tggtgctaaa gctcaaggtg
     8641 tttctgtatc tgaatttagg gctatgctac aagataccat agacaaaact atggaaagta
     8701 cagacccaga cgtgcaggca aattttaaac gatactttgg aaataagcgc ccaacaccag
     8761 aggaatatat ttatacgatt accaaaaaga caaaggttaa ggtttaaatg ttgtaaaggg
     8821 ggcttgccgt atgaaacgct ttatgtacaa ttcagtatat tcaagcccaa tttaacagca
     8881 tactatttac aattaaatac gctataccag tagctcgtac aaaatttata ttttgtgcgg
     8941 gcttttttaa tacccgaaaa gtttttttaa ttattttcat ttttttggaa gcaaatcaca
     9001 ccttgctgta cagatatggt gcggaaagag ggataaacac ttttcaattc atagctggaa
     9061 aggaggtgag attatgaaac cgtctgactt ccaaaaaaca attcagtgtc agtttgaatg
     9121 taagctgaaa aaagttgtca aaggtattat ctggaactac cgtaaagaat taaaacgaag
     9181 aaaaaacaag gaaatatctt ttagcgaatt accagacatt acggtagaaa gtctggcaac
     9241 atgggacgac tacgaaacaa actacacaat ttttaatgtg tgtggcatag atattaaagt
     9301 ccttgatgat gaacttgcag aagctctcaa acagctaccc gaaaaaaaac gtaacaatgt
     9361 attgatgtat tacttcttgg aaatgagtga tacagagatt gcagatatta tgaattatac
     9421 cagaggggct gtgttcaaac acagacaccg tgcactagaa actatgaaag agatactaaa
     9481 ggagaagaaa tagaaatgaa gaaaaagtac aagcacccgt cttattattt gatttcatca
     9541 gctatggatg gggatgaaac tgcgattgag aaattactgg cattctatga cccgtacata
     9601 tcaaagtgtt gtttacgtcc tttatatgat gaatacggca atgtttatat tgttgttgat
     9661 atggaattaa agggacgtat tcgagaagcc ttaatcaaaa tgattttaga ctttgagatt
     9721 gatatagata tagaaaccga agaagaataa gcaaatacca gcagggcgtg attggttaaa
     9781 ttcccttctt tcctgccctg ctcctgcttt tatacatgga agcctacggc tttcgccgat
     9841 tgttctttga caactgaata aagcagacag atacgtttgt gatacagcga gccacgggga
     9901 ctgtacgcca tgacctttcc gacaagaaag cgagcgaccc acgcagttga tccgagagcg
     9961 acttgtggaa tggtcgtttt gccatgacct gctatcacag aataatgata cgtccgcatg
    10021 gtgcggttct gcccacaaga atgggaatag ttgagatact aacggagctt tccaaagccg
    10081 tctgtctgct tatgataaga cacacagaaa ggagttgttg caacatgaac aatactgatg
    10141 tgccgatttg ggaaaaatac acccttagta tagaagaagc gtcccgatat tttcgtatcg
    10201 gggaaaagaa gttgcgtaaa cttgccgagg aaaatctgga ctctggttgg gttatcgtta
    10261 atggaaaccg tattcagata aagcgaaaac agtttgaaaa aattattgat acactggacg
    10321 aaatctgatg tcttagagcc gtagatatgg tataatatta gtagcgtatc acggctcatt
    10381 ccatgacgga aaggagcttt acactatgtc aaaaatgaaa agacaagaca gtaaaggacg
    10441 caatttgcgt cttggagaga gccagagaaa agacggaaga tacgtttata aatataccga
    10501 tatattcggg aagccacagt ttgtatatgc ttggaaactt gtaccgacag acaaaacacc
    10561 tactggaaaa cgtgatgata aatcattgag ggaaaaagaa aagcagataa aaaaagacct
    10621 tgacgacggt atcgacacta tcggcggtaa aatgacagtc tgccagcttt atgcaaagaa
    10681 gaacaaccag aaaaagaaca tcaagagaaa cacggaaata ggacgacagt atcttatgaa
    10741 cgcactagaa aatgacccat taggtatgag ggcgattgat acagtcaaac agtccgacgc
    10801 taaagaatgg gctatcagaa tgaatgacaa aggttattcc tataagacaa tagataacta
    10861 taagcgttcc ttaaaggctt cattctatat ggcgatacaa gacgactgta tcagaaaaaa
    10921 tccttttcat ttcaagctaa gtgatgttct ggaagatgat acagagccta aagttatctt
    10981 gacaccagag caggaagaaa aacttctttc ctttatggaa acggataatg tttacagcaa
    11041 gtatcgtgat gaagttattc ttctgctgga aacgggactt cgtatctctg aattatgcgg
    11101 actgacaaca cacattgata tgcttaatcg tgtgattaac atagaccacc agctattacg
    11161 tgatacagag gtgggctact atatttccac acctaagaca aaaaacggca agcgagagct
    11221 tccattgaca gaaagagcat atcaggcact tgaacgaatt ttaaagaacc gaggaaaagc
    11281 tcaaccgctt gttgtagacg gttatagcaa tttcttgttc ttgaaccgtg agggcttgcc
    11341 aaaggtagca ggaaattatg aaagtatggt gcgtgggctg attaagaagt acaacaagac
    11401 ccatgaggac aagttgccga acatcacgcc ccactcattc agacatacct actgtacgaa
    11461 catggcaaat aagggaatga accctaacac cctgcaatac atcatgggac acgcaaacat
    11521 aaccatgaca ttagggtatt atgctcacgg tactttccag tctgcaaagg cagagttgga
    11581 aaggctggct tcttaatatc gaaaatgtat cttactactt atttactact tttggttgca
    11641 ttttcatgct ggtaaatgcc agcttatgcg aggtatcttc caaaaagaaa atgcccatac
    11701 agcccgaaaa tacgggatat atcggcattt accaacttat gaaaagataa tcagaaatta
    11761 gtaagttttt atatcaaaaa aatgattact gtaaagaaat cattttttat tataatcact
    11821 gatacatcaa atattctaaa taaaattttt atttatctgg aattgtatat tttttctata
    11881 atattaacta cagcgtacat tgcccaagca cagatagcca atacaaatac tcccatcatt
    11941 actaaatcta atttaaatac ttgagaacca tatactatca agtagcctat tccatatctt
    12001 gaaactaaaa attctccaac tattacacct acccatgcca taccaatatt aattttagtt
    12061 aaatttatta aatttcctgt gtttgcaggt aatatgagtt taaataatat ttgagattta
    12121 gtagctccaa aactttttaa catcttaatt ttttcttcat ctatattcat aaaataatta
    12181 taagctgaaa gtatagtaac aacaacagaa atcgttacag ctgttacgac gattccttct
    12241 attccagcac ctacccaaac tataattata ggagctaaag cagtcttagg aagagcattt
    12301 aaaactacca aaaatgggtc taatattttt gataattttt ctgaccacca aagagcaatt
    12361 gctaccaaaa tacctaatac agtacctata acaagaccaa gaacagtttc atatacagat
    12421 attccaatat gtttaaataa ttgaccacta aatgcatatt gaataaataa attgtaaata
    12481 tcacttggtt tgctaaatag aaatgtattt ataacattta agtcagctaa aagttcccag
    12541 attacaataa aaccaattaa aattaatagc tggtagaata atacatttct tttttctctt
    12601 tttacacctt taacatagtt tatatatcct tcagatcttt tattaagcct catgtgtatc
    12661 tagctccttc cataatatgt cgaaatactt ttgaaaatca ggaactttac gtgttttgag
    12721 aggcgttttt gttccatcca tgttaagttc aatatcgtaa atatttttta tggtagctgg
    12781 tcttttagat agtattgcaa ccttatctga tatgcttatt gcttctgcta tagctaaaaa
    12841 agtgcaacta attgcttaaa gaaacagaat tatcaacttc agcacccata taaacaatat
    12901 taagatttcc taaactgcta tcccaaacga tactattaat aatagtagat aataacaatc
    12961 tcttatcatc taaactggca ttatcaactt catcattaaa tctcttcaaa ttactaacaa
    13021 taatatcaat attaatactg tcactactaa tattgatgtt actagattcc aaaatattaa
    13081 tcttatcctt taaaatacta atctcattat ttaggctctc aatctgggaa actatataat
    13141 cagaagcagt actaccagta ttttttgcaa gctctataac taaattttta ataagtcttt
    13201 ccttatctaa aatttgattt ttaagtaaat tagtctcaga tttaaaaata ttaaaaacat
    13261 tatcagtctt aatgttatta ctattgaatg cacttataat agactcttct ttacaattct
    13321 taattttatc tataactaaa ctttcaacta atggaccatt aagattttta cagttgcaac
    13381 tatcagaccc aagtgttttt ttagtaccac aaatataata atactttaaa tccttgtcag
    13441 tttttttgcc tttataggta attctcatat tagaaccaca tttaccacat tttataagac
    13501 cagataaaag agcagttttt ccagttgata tccttggagt tttatcacga tttttatcta
    13561 attgattttg tacttcaagc catatttcag gttctatgac tccatggtgt tttgcaattg
    13621 ctgctattga gttagatgta tttttagcat aggtaaggat tccacatttt ctatctggag
    13681 tacctacaac atccatacca ctatttttaa ggtaatctaa aatttcatca ttagctttta
    13741 catatgctgg atttctaagt attctagata aagaactagg gtcaaatttg ccaccacgag
    13801 gaccccttat tccattatta tagacatatt tatataactt agataaggac ctaagttcta
    13861 aatatttatt gtatattagc tttacaatct ccatttgttc atcatttact tgaagcttat
    13921 acatacttct ttcttttaga ttttcatcta agaatgtgat tttttcactg ttgaatccat
    13981 gaggtgtatt gcctccaagc catctaccac tacgggctaa ttcatacata ttgtctttta
    14041 tacgttctgc tattgtttct ctttctaatt gagcaaatac acttgatata aacatcatag
    14101 ctcttcccat tggagttgaa gtatcaaatt gttctttgat agatataaat gatatgctta
    14161 gttcatttaa tttttctatt aaagtagaga agtcagatac atttctcgat atcctatcta
    14221 atctataaca aactaggtaa ctaaatttct tatctttggc atcctgcatc attttcttaa
    14281 attgtggtct atctatattg ctaccactaa atccctcatc ttcatatatc aaaaaatctt
    14341 ttacaccaat agactttgca taatcaatac ataattgtat ttgattttct atagaatcac
    14401 cttttccagt aaatcttgat tttcttgaat aaattgcagc tttcaaaatt aaaaccccct
    14461 ataagttagg atatatattt gaaactattt atctacaacc ttttaagtaa acttattaga
    14521 atgaatttat taattaggta aatttatata attctacttt ttataatata tgactattta
    14581 ttttatttct ttactattca agttctaaat caataataaa ttttgatatt taattgtatc
    14641 aggacaaatc tctaatttca tagattatta atataaaatc ataggttagt gtgaaaaagt
    14701 tgaaatttaa atattttaaa agataatttt tttgaactaa taggtataac aaaaatttat
    14761 agggggattg catatggaaa tcaatgttat agaaattttc cctaaagata aagctaaact
    14821 taataaaata gaaatggata aagctagttg gtttgtaaat ataataagta aaaaatatcc
    14881 taaagaagct ttaaatgaag catttagtac tttagaaaaa gaattaaata taagtaaagc
    14941 taatacataa gctttgatta ttgattttat atactattgg ttttatacgc tatgacttga
    15001 cattatatta atcaaatagt atatttttaa atatagcaca atgaagtgtt aaaagagcaa
    15061 tggagctcca tagataaagt ctatggagct tttttgcgta tttaacttaa ggaggatagg
    15121 actttgaata actttgagat taaaactaga ataaaatttg gagaaggctc actaaaagct
    15181 ttgcaagaat taaaaaacaa aaatgtacta ataataacag acccttttat ggtgaaatca
    15241 aaaacaatag ataaaataac atctaattta ataaactcaa catatcaagt ttttgaagaa
    15301 atagtaccag acccaccaat agaagtagta gtagcaggaa tagaagcatt taaatctata
    15361 aatccagacg taataatagc attaggtggt ggttctgcaa tagatgcagc aaaatctata
    15421 atggactttt ctaaaaaaat attaaaaatt aacgaagtag agtttatagc aataccaaca
    15481 acaagtggaa caggttcaga agtaacatca tttgctgtaa taacagatag tcaaaaaaaa
    15541 tgtaagtatc cattagtgag tgatgattta cttccagata tggcaatact agacccagaa
    15601 cttgtaaaaa ctgtaccaaa ttttataaca gcagatacag ggatggatgt attgacacat
    15661 gctatagaag cttacgtatc tacaaattct aatgactttt cagatgcact agctgaaaaa
    15721 gctataaagt tagtatttaa atacttaata aaagcatata aagatggaaa tgacatagaa
    15781 gctagagaaa aaatgcacaa tgcatcttgt ttagcaggta tggcatttaa ccaagcatca
    15841 cttggcataa atcattctat tgcacatgta ttaggtggaa aattccatat accacatgga
    15901 agaacaaact ctatattact tcctcatgta atagaatata attcatcaat agtaggatat
    15961 actaacacaa cttactctgc tacagctaaa aaatatgcac aaatagcaga attagtagga
    16021 cttgggagtg ctaatataag aatatctgtt agaaatttag taaatgaaat aaagaaacta
    16081 caaaaagaaa tgaatatgcc aactaaattg acacaatgca aattaagttt agaagatata
    16141 actaatgaag aaagagaaat agcaaaactt gctataaaag atacttgtac attaactaat
    16201 cctaaggtac caactgaaga tgatataata aacatattaa agaacattaa ataactacat
    16261 tttattacat gtaaatataa tattatacaa atagggaaaa tgtttttaaa aatataaatt
    16321 atatattgac aaatataaaa cataaaacta taatgaaagt atcacaaagg cgtgatactt
    16381 tagtagaaag caatggagct tcttaggaat attaatatta ttcttatgga gctcctttta
    16441 ttttaatcaa atagcttttt aataaactat attcaaagaa agcagggaat aaatttgact
    16501 gaagaatcta agcaaagagt tattcaagaa tatgttcctg gaaaacaggt tacattagca
    16561 catatcatag ctaaccctaa tgaagatata tataagaagt taggattagt acttgataaa
    16621 aaagatgcaa taggaatact tacaataaca ccaagtgaag cgtcaataat agcagcagat
    16681 gttgctacaa aggcttcaaa tgtatcttta ggttttatag atagatttag tggttcagta
    16741 gtaatatcag gtgatgtaag ttctgtagaa tcagcgttaa atgatgtttt agaagtctta
    16801 ggaaatatgt taaacttctc atctacaaaa atcacaagga cataataata caatgaagaa
    16861 tataatattt atgggaaaga caggtagtgg taaaactacc ttatgtcaaa aactagacca
    16921 gttagaatta aagtataaaa aaactcaatc agtggaactt tataataatg caatagacac
    16981 tcctggtgag tatatggaaa atagaaacct atataatgcc ttaataacaa catcagcaga
    17041 tgctaaaatt atagcaatag tgtatgatgc cacacaagaa gaaaattata tagcaccagg
    17101 ttttgccagt atgttttgca aagacgtaat aggaattata actaaaataa ataaagctac
    17161 tgaaaacgaa gtcaatatag cttatgaaag actatcacta gcaggagcaa gtcaaatctt
    17221 taaaatagac acagttgata atattggact tgaaaaatta tttaaatatc tagaaaaata
    17281 taaaaatata gatgaagttt aaggggaaat atttttttat tcaaaaatat tattaaagta
    17341 tgataaaata aaaaaatgta taaactattt taagaagatt taatctttaa gcgaggtagg
    17401 aacatgggga aaaaaatact attggttgat gatgaaccac tgttaaggat ggatacaaaa
    17461 gatatattag aaagtcatgg ctatgaaata ataggcgaag caagtgatgg atttgaagct
    17521 gttgaaatgt gtaaaaaaca caaacctgat ttagttataa tggatataga gatgccaata
    17581 cttgatggta taaaggcagg caaaataata tgtaaagaaa atatagctgg tggagtactt
    17641 ttattaactt catttgaaga taaagaatac gtagaaaagg ctaaaagtat aggtgcttat
    17701 ggatatttag taaaaacagc aagtgaaaaa tcacttatcc caaccataga aatgtgttta
    17761 aataaggtaa atgaatttga aaaaatgaaa aaagatttag aaaaagtaaa ttctaaattg
    17821 aatgaaagaa aattagtaga aagagcaaaa ggtatactta taagagagtt taagatttct
    17881 gaggatgaag catacactag aataagaaaa ttaagtatgg ataaaagaac tacaatgatg
    17941 gaaattgcca aaatgattat aataggatac gatgactaat acgataaaaa aaatatcaac
    18001 tgcacaaaca tacttaaata ataacgaaat tgaaaaaatt atagaagtat caaaatcctt
    18061 agatttaatg gcttcttttt atgaagctga tgtttttata gatgtactaa gtaaatttga
    18121 tgatgaagca attgttgtgg cacatggtag acctaaagaa aagtcaatgt actgtgaaaa
    18181 tgttataggt aaaaaggctt taattgaaaa tgaaccagga gttataaagt gcttaaaaac
    18241 aggagaaaga gtaagagata ttaaagcttt aacacaggaa tataaactgg tcaaacaaaa
    18301 tattcagcca ataacactag atgacaaagt tttagcagta ctaatagttg aaaaagatat
    18361 aagtagtgaa gttaagaatg agtttaatgc tagtgaagac gaagaaaata aaaatttaca
    18421 tcagtttata aaacttattg gaaataatga ctttttagtt gataatttaa attcagccat
    18481 attaatattt gataaaaatg gaaaattaaa aattaaaaat cgtattgcaa ctgagatata
    18541 caaaaatctt gggtttggat atgatataca agatatgcat tacaatgatt tagatataga
    18601 aaccaacacc tttgaaaata tattaatgga tgaaaattat gatgagacaa atgaagtttc
    18661 aataggtaat atgtttttta aaataaagac catatacatc aaagatgatg aatttaaggt
    18721 ttgcaaaata gtacaagata taagtgattt aaagagaaaa gaagaagaat tagttttgaa
    18781 aacagtggct ataagagaag ctcatcatag agtaaaaaat aatcttcata cagtaatatc
    18841 tataataaaa aaacaaagta gattatctca aaatgatgaa gtaaagcagt gtttagataa
    18901 cataataaat agggtatttg caatactttc gactcattat ttactatcta aagaagttga
    18961 taataatata tctatacgag aaggtatcaa tttattagtg tcaaatattc aaggtggcta
    19021 tttatttagt aaggatatag atatacgtat aactggtgaa gattttaaaa ttagtggaga
    19081 aaaagcaaca gcaatacttt tggttataaa tgaaatacta caaaattgtt atgaccatgc
    19141 attttcggat agagaacatg gtactataca aatattaata aataaagata acgactatag
    19201 aaatattgct attatagatg atggaattgg atttgatagt aataatataa ataaaaatag
    19261 cttagggaca tatataatag atagttatat aacacagatg ttaaaaggaa atatagagag
    19321 aaaaagtagt gagaatggta cagaagtatt aattactata cctacacaaa ttaatattta
    19381 aataataact catctacaaa gtagtagttt taattgagca aagaggctta aggttattaa
    19441 tagattaagt taattgaatg tatttataaa aattataagt atatattcaa tttaacaggt
    19501 atttattata actttaagcc tctttgcttg tttaagacat acttaaattt taggaggtga
    19561 gaaaatgaga gaagagttat taagtgttgg tattgacatt ggaacaagta ctactcagtt
    19621 aattttttct aaattaatag tagaaaatac tgaatcaaat ttttcggtac ctagaataag
    19681 tatagtagac aaagaaatta tttataaaag caaagtttat ttcacccctc ttatttcaaa
    19741 taatgaaata aatggtcaac aaataaaaga tatagttgaa aatgaatata aaaaagcaaa
    19801 tatatctaaa gaagatatac atacaggagc agtaataata actggtgaaa cagctagaaa
    19861 agaaaatgca aatgatgtac ttcatacttt gagtggattt gctggggact tcgttgttgc
    19921 aacagcagga cctgatttag aaagtataat atcaggaaaa ggagctggag ctcatattta
    19981 ttcaaaagaa cattcaacta caattgtaaa tatagacata ggtgggggaa ctagtaacat
    20041 agcctcattt aaaaggggag aagtaaccga tactgggtgt ttggatatag gtggaaggct
    20101 tgtaaagata gataaaataa gtaaaaaaat aacttatata tcacctaaaa tagataaaat
    20161 cataaaagat aataatttaa atcttcaagt aggtacaatg gctactgtag aaaatacaaa
    20221 gccaatagtg gatataatgg ttgacttatt aatggaaagc ataggactaa agaaacagac
    20281 acctttgttt gattttataa taaccaataa atcaataagt atagatgaaa atattaaaaa
    20341 tgtttcattc tctggtggag tagctgatta tatttactat gatggagaaa taaaagatta
    20401 ttttgaatat ggtgacttgg gaattttact tgggcaagca ataaaaaatt gtgaatacct
    20461 taaaaaagta aatgtagtta aatctatgga aacaataaga gccacagtgg ttggagcagg
    20521 ttctcatact actgaagtaa gtggaagtac aataacttac actagcgaaa agtttccact
    20581 taagaacttg ccagttttaa aattatcaat tgatgaagaa acaggtactt caaaacaaat
    20641 cagtgaagct ataaaaaata aacttaattg gtttaaacta gaaaatgatt tacagaaagt
    20701 tgctatagcc atgataggaa agaaaaatcc aaccttttta gatatacaag agtatgctaa
    20761 agggtttgta gatggaatgc aacaaatcat agaaaatgat ttacctttta tagtaattgt
    20821 tgaaaatgat atggcaaaag tgttaggtca agcaatatat gcattattaa attatgaaaa
    20881 agaaattgtt tgtatagaca gtgtcaaggt tgaaaatgga gactatatcg acattggaaa
    20941 acctatagtt gaaggtaaag ttttacctgt ggtaataaaa acattagttt ttaattaata
    21001 gaaggaggta agtaaatgat tttaaataca aaattatttg gacgtactta tcagtttaaa
    21061 ggcttatatg atgtaatggc taaagctaat gaagaaaaat caggagataa attagcaggt
    21121 cttgcagcag aatcagctga agaaagaata gcagcaaaag ttgttttatc acacataaaa
    21181 ttggaggata taagaaataa tcctgcagtg gcatatgaag aagatgaagt aacaagaata
    21241 atacaagatg ctgtaaatga aaaagtttat gaagaaataa aaaattggac agtgtctgaa
    21301 cttagagaat ggctattgga ttcaaatact acaagtcttg atataagaag aatatcaaga
    21361 ggattaactt ctgaaatgat agcagcagtt gcaaaattaa tgtcaaatat ggacttagtt
    21421 tatgcagcta aaaagataaa ggttactgct cactgtaata caactatagg agaacaagga
    21481 acattatcag caagacttca acctaatcat ccaacagacg acccagatgg aatacttgca
    21541 tcacttcttg aaggtttaac ttttggtata ggagatgcag tacttggatt aaatccagtt
    21601 gatgactctg ttgagagtgt tactaaagta ttaaaaagat ttgaagaagt aaaacaaaaa
    21661 tatcaaatac caactcaaac atgtgtattg gcacacgtta ctacacaaat ggaagcaata
    21721 agaaatggtg ctcctgcaga tttaatattc caatctatag caggttctga aaaaggaaat
    21781 gaagcatttg gatttaatgg cgacactata gaagaagcta gacagttagc cttaaaacac
    21841 ggtacagcta caggacctaa cgttatgtat tttgaaactg gacaaggttc agaattatct
    21901 tcagaagcac atcatggaat agaccaagtt actatggaag ctagatgcta tggatttgct
    21961 aaaaagtatg aaccattctt agtaaataca gttgttgggt ttataggacc tgagtactta
    22021 tatgatgcta gagaagttgt aagagcagga cttgaagacc actttatggg taaactacat
    22081 ggcttaccaa tgggtgttga tgtttgttac actaaccata tgaaggctga ccaaaatgat
    22141 atggaaaact tagccatact attaacaaca gcaggatgta cgtattttat gggaatacct
    22201 catggagatg atgttatgct taactatcaa acaacaggat accatgaaac agcatcactt
    22261 agagaaatgt ttggactaac agcaataaaa gaatttgatg cttggatgga aaagatggga
    22321 ttctctaaag atggtaagtt aacagagttg gcgggagacg catctgtatt attaggatag
    22381 gaggtattta atatgaatga gaaggattta aaagcattgg tagaacaatt agttggacaa
    22441 atgcttggag aattagatac taatgttgtg tctgagactg ttaaaaaggc aactgaagtt
    22501 gtagtagaca acaatgcttg tatagatgat ataacagaag ttgatataag aaagcaatta
    22561 ctagtaaaaa atcctaagga tgcagaagct tatttagata tgaaagcaaa aacacctgca
    22621 agattaggta taggaagagc tggtactaga tataaaacag aaacagtttt aagatttaga
    22681 gcagaccatg ctgctgcaca agatgctgta ttctcttatg tagatgaaga atttataaaa
    22741 gaaaataata tgtttgcagt ggaaacttta tgtaaagata aagatgaata cttaacaaga
    22801 ccagatttgg gaagaaaatt ttctccagaa actataaata atataaaatc taaatttggt
    22861 acaaatcaaa aggttttaat attagttgga gatgggctta gctcagctgc aatagaggca
    22921 aatttaaaag actgtgtgcc agctataaaa cagggtctaa aaatgtatgg tatagattca
    22981 agtgaaattt tatttgttaa acattgtaga gttggtgcta tggaccactt aggtgaagaa
    23041 ttaggttgtg aagttatatg tatgttggtt ggagaaagac caggattagt tactgctgaa
    23101 tcaatgtcag catatatagc ttataagcca tatataggaa tggcagaagc aaaaagaaca
    23161 gttatatcaa acattcacaa aggtggaaca actgcagttg aagcaggtgc tcatatagct
    23221 gaacttataa aaactatgtt agataaaaaa gcttcaggaa tagaccttaa ataaagtcga
    23281 gggagtgtag aatatgaaaa atgatgtaat tcgtcctaat atactaggaa ttaaaataat
    23341 ttcaaatata agtccagaaa tggcacaaaa actagaatta aaatcacatc acaaaagctt
    23401 aggtttaata actgcagact gtgatgatgt tacgtataca gctcttgacg aagcaactaa
    23461 agcttcagaa gttgatgttg tatatgcaaa atcaatgtat gcaggtgctg caaatgcttc
    23521 aacaaaactt gctggtgaag tattaggaat aatagcaggt ccaagcccag cagaagtaag
    23581 aagtggtcta aatgcagtag ttgattttct agagtatgga gcaactttta taagtgcaaa
    23641 tgatgatgat tcaatagcat actatgctca ctgcgtatca agaacaggta catacctttc
    23701 agaggtagca ggaataagag aaggtgaagc attagcttat ttagtagcac caccacttga
    23761 agcaatgtat gcactagatg cagcaatgaa agctgcagat gttaagatgt gtgaattatt
    23821 tgcacctcca actgaaacaa actttggtgg agcattactt acaggttctc aatcggcttg
    23881 taaagcagca tgtgatgcat ttgcagaagc agtaaaatca gttgcagaca atccaacagg
    23941 attttaagga tagttagatg gatgctatag gcttaataga agtaatagga tatgttgctg
    24001 caatagaagc ttctgatgct tgtttaaaat ctgcaaatgt taatattgta agagttgata
    24061 aggttggggc aggtattgtt actttaacaa tatgtggaga tgtcggtgct gtaaaagctg
    24121 ctttagaagc gggtgaaata gcagcttcca gagttggtac attaagaaca tcacatatta
    24181 taccgagaat ccataatgaa gtaacaaatg ctttattcaa aactaaagaa cctaaagtct
    24241 gtgaagtttc agaagataaa gaaaaaaact ttgagattac attggaaata gctgataatg
    24301 tatcgaaaaa tttatcagaa aaagaaaatg taattttaga tgtcaatgaa aacagtggag
    24361 atactgaaaa tttatatagt gatatagata aaacaaacaa aaaaattgaa acagttgatg
    24421 atagtttaac agaagctaat gaggaaaaaa tagaaaacac taatgataaa gaagtattgg
    24481 aacaagttaa aatagaaaat tccgattttg atagagatga cctatcaaag aacagtgtaa
    24541 aaaaacttaa agctatggct aaaaaattag attcttcaat aacttataaa gacttaaatg
    24601 ttcttaaaaa agaagaatta ataaacttag ttaaaaagct tagcagaagg gatagatagt
    24661 tatgacactt ttagataaag atttagtatc tatacaagaa gtaagaactc ttgtaagaag
    24721 atctaaagtg gctcaagaga aactttctaa aatgagtcaa gagcaaatag ataaaatagt
    24781 aaaagctgtt gtagatgcag catttaataa tgctactaaa ttagctaaaa tggcaaatga
    24841 agaaactgga tttggaaaat gggaagataa agtaattaaa aatacttttg catctatggg
    24901 agtttatgaa actttaaaga acacaaaaac tattggaata attggtgaag ataaagaagc
    24961 caatacgata gatatagcta caccagttgg agttgttgca ggtcttatac cttcaacaaa
    25021 cccaacatca acagtaatat acaaaactat aatatctcta aaagcaggaa atactatagt
    25081 tttctctcca catccaaatg caaaaaactg catacttgaa acagttaata taataagtga
    25141 ggctgctata aaggctggag ctccagagga ttcaatatta tgtataacta atccaagtat
    25201 agttggaacc aatgaattga tgaaacataa agatacaaac ttaatactag caactggagg
    25261 agaagcaatg gttagagctg cttactcttc aggaacacca gctattggag ttggaccagg
    25321 aaatggacca gcatttatag ataaatcagc aaatgttaaa ttagcaatca aaagaataat
    25381 agattctaaa acttttgata atggtgttat atgtgcatca gaacaatcta tagtaataga
    25441 aaaatctatg gaagaaactg ttttaaaaga gcttaaaaat caaggtgcat atgttttaaa
    25501 tgaagaggaa agtgaaagat tagcaaaatt catattaaga gctaatggta ctatgaatcc
    25561 acaaatagtt ggtaaaagtg ttgaggtaat agcaaattta gcagacttaa caaatgtacc
    25621 taaaaataca aaagttctag ttgcaagaga aaataaagtt ggtcacaatg tagcctattc
    25681 aagagaaaaa cttacaccaa tactagcgtt ctatgttgaa gaaaatgtag aagctattat
    25741 gaacagatgc agagaaatat tgttaaatga aggtgcaggt catacattct caatgcatgt
    25801 aaatgatgaa gaattggtaa aaagatttgc ccttaatatg ccagtatcaa gaatacttgt
    25861 gaatactcct tcagcacttg gaggaatagg tgcatcaaca aaccttgtac cagcactaac
    25921 acttggttgt ggtgcaatag gtggaagttc aacttcaaac aatataggac cacttgattt
    25981 aataaatgtt aaaagagtag cttatggaat caaagaaata gaagaacttg gaagagataa
    26041 atctcaagtt gaaaaatcaa tgtttgactc aatggataaa gaagaattaa taaatcttct
    26101 tgttcaaaaa ctagtcaaag aactagcata actaaaataa acaatgaaac ttatggctat
    26161 cgctataaat ttctaaaaat ataaactata aaaaactata aaattaaatt tttggaggat
    26221 aagattatgg caagtgcaaa cgcattagga atgatagaaa ctaaaggatt agtaggagca
    26281 atagaagcag cagatgcaat ggttaaagct gcaaatgtac aattagtagg aaaagagcaa
    26341 gtaggtggag gattagttac tgtaatggta agaggagatg ttggagctgt taaagctgct
    26401 acagatgcag gagctacagc tgccgagaga gttggagaac taatatcagt tcatgttata
    26461 ccaagaccac actttgaagt agatgctata ttaccaaagg tatcagctga gtaatataag
    26521 aataattata aaatttaaat tttgattgaa aaagaggcta tctcaaaaat gagtcttact
    26581 aataaactca atgtattttg aggtagtctt ttttatacat ctaataggag atgtgataaa
    26641 atgggtgttt taacagaaaa cgaagtaaaa agaaaaattg gaaaaaacaa aaataatata
    26701 actgaatttt atatagaaaa aggtcaaata ataactcctt ctgcaaaatc ttatttagct
    26761 gagagaagta ttgagcttaa atatgttgat aaactttcag atgtaaacaa tgaacctaaa
    26821 gaagttgtaa aagaagtagt taaagagaaa aaatataaat atactactgt atttggcgcc
    26881 aaattggatg aaaaaccaga acatatgact caattaaatg gaaatctttt agtttttaaa
    26941 gaccataaaa gaataatatt gagaggaaaa atagattctc ttgaatcaga aatactaaag
    27001 gtacagatac tttgtcagaa actagatatg ccaaagcttg ttaaggaatt gcaagaagta
    27061 ttagactttg taagaaatat aatgagatgt gaagttttag atgaaaagct aggggacttt
    27121 aaacttttag gattaactcc tcaagaactt agagaacaat ctcactatcc taaaaaatac
    27181 tttggtatag gacatgagtt cccaagttat gaaatgggag aagtagtagt agctataaat
    27241 agtataagaa gtaatacacg agaggttgaa cttgcagcct atgaagcatt taagggtgag
    27301 tatggaaatg ttcacagaga agatttaata aaggcactta atagattatc gtcagtattt
    27361 tggataatga tatataaggt tagaactaat aagtataagt agttggagga cataatggag
    27421 aatctattaa atgaaatagt ggaagaagta ataactagag ttaaaaaaga agcatttata
    27481 gaagttgaag catcaggaag acacgttcac ttaagtagag aagatgtcga taaattattt
    27541 ggagaaggat atactcttac aaaactaaaa gacctatctc aaccaggtca atatgcatgt
    27601 aaggaaagag ttacaataac tggtcctaaa ggaagtataa aaaatgtagt tgtacttgga
    27661 ccatgtagaa atgaaactca ggtagaaata tctttaacag atggttcaac tcttggacta
    27721 aaagctccta taaaacaaag tggagactta gaaggtactt taagtattaa aatatcaaca
    27781 caatatggtg aagttgaact tgataagggg ctaatggttg ctaaaagaca tatacacatg
    27841 actcctaaag atgctgaaaa attcaatgta tgtgataaag agatagttga agctaaggtg
    27901 atgggtcaaa gacctttaac atttgatgat gtagtaataa gagtgagtga cagttttaaa
    27961 acttatatgc atatagacta tgatgaagcc aatgcatgtg gttattcaaa aggaactgtt
    28021 gctaaaataa taaagaaagc ataaatttaa cctactatat aaattacctc tagggaggat
    28081 ttaatatgaa ttatgataac cttgtagatt taataacgga agaaatctat aaaaaaataa
    28141 atagtaatga aataaaaata tctaataaac ctaaagctgt gattgtattt gaacaagata
    28201 acaataaatt taacttatta aaagatggat ttgaaatagt agaatttgat aaaagtataa
    28261 gggaatgtga aatagtgata gtttcaagac tttgtatgag ggggctatcg aatatagcac
    28321 ttggaaattc aacaagtgat gaagaaagat ttatactaaa aatgattatg aatggcaaaa
    28381 aagtatatgt cctagatgaa ggaattgaat acaaaaaata taaggatact gcaccaaaag
    28441 cactatataa gaaatttatg tcatttgaag atgaaatatg taaatttggt gtagaaatta
    28501 taaaagactt aaatgttata actaaaaata agttaaatat aaagaaagaa ctagaaagta
    28561 ctagaggttc taaaaaagaa gatacaaaag ttttagataa agatatttta aatttaacca
    28621 gtgtagaaag tgtaaaaata gataatgaat ttagtttgga tttaaggaat aaaaaactta
    28681 tatcggaagc tgacttaaga aaaccaacta taaatggagt taaaaacata ttagttaata
    28741 aaaaaagtat aataacacca ttagctgtag attttatgag aatacaccat ctcaaactaa
    28801 agaaactgta aggaggtaat tttatggata taggaaaagt tgtaggtaat gtttgggcta
    28861 caagaaaaga tgaaaaatta tgtggccaaa aacttttagt tgtaaaaatt ttaaaaacta
    28921 aagacacata caaggaaggc ttcatggttg cagccgataa tgcaggagca ggaaatggag
    28981 acttagttct tatatccaaa ggttcctcag ctagagagtc gattgaaaaa tctcatgttc
    29041 cagtagatgc aactatagtt ggagtagtcg attcgtttga ggtgtttgat gaataaaagt
    29101 ataggagcta tagagtttaa aagcattgct aaaggtatag aagtatccaa tgaaatgata
    29161 aagaaatctt cagttgatgt attgtactta aaaagtattt gcccaggtaa atttctaata
    29221 atagtaggtg gagaaacttc ttatataaat gaatgtgtag attatggaat aaaacttgga
    29281 gaaggatata ttgtagataa cttcgtaata aatgcaattt cacaagaaat attagatgga
    29341 tttaaaaata agtatcaaaa gctagatagt atagtctcta taggcgttgt tgaaagtagt
    29401 aaaatatgcg ctggaataaa aatgcttgat aagactttaa aatctggcga cttagtatta
    29461 gtaaaacttc aattatcttt tgctataggt ggcaaattag tatatatagt agcaggagat
    29521 ttaagtagtt tagaatatgc attaaaagaa agtgaaaatg tagtaagaga aaaagaagta
    29581 atatataaga ctgtaatacc atcagtagac agtcaaataa taaaaagtct aataaaataa
    29641 tggggggaat tatgagtata aacgaaatta taatctatgt aatggtagtc ttcatggtac
    29701 ttggagctat agataaatgt ataggtaaca aatttggtct tggagaacaa tttgaggaag
    29761 gtataatggc aatggggtca cttgcagttg caatggttgg tgttatatgt ttagcaccag
    29821 ttcttgctga tgtattaaga ccaattgtag taccagtatt taatatactt ggagctgacc
    29881 cagctatgtt tgctggaagt ttattagcta atgatatggg tggtgcgcca cttgcacttg
    29941 aacttgcgaa agaccctaat gctgggttat ttggtggatt aatagtaggg gctatgatgg
    30001 gacctacaat agtatttata ataccagttg cgcttggaat aattgaaaaa gaagaccaaa
    30061 aattcttagc aacaggaata cttgcaggta taataacaat acctattgga gcattcgttg
    30121 gtggattagt tgcaggattc gaggtaatga tggttcttag aaacttagtg ccaataataa
    30181 tatttgcagt agttatagca cttggattat taaaattcga aaatgctatg ataaaaggat
    30241 tcacatactt tggaaaaggt gtagtaatag ttataacttt aggacttgct gctgccatag
    30301 ttgaagcttt aacaggaata gttgtaatac ctggaatgaa accaatcagt gaaggtatag
    30361 aaatagttgg agatatagca atagttttag caggagcatt cccattagtg tttgttataa
    30421 caaaggtatt taataaacca ttaatggctt taggaaaagt tcttggaatg aatgatgtat
    30481 cagcagcagg ccttgttgca agtttagcta actgtatacc aatgtttggt atgatgaaag
    30541 atatggacaa tagaggaaaa ataataaatg tagcattctc tgtatcagca gcattcgtat
    30601 ttggagacca cttaggattt acggcaggat ttaattctaa tatgataaca ccaatgatag
    30661 ttgctaaatt agttggtggt ataacagcag tattgttagc tatggttatc gcaaataaga
    30721 cactaaagaa ggagaatgta taagatggat atatcaaata tagataaaaa tttaattgaa
    30781 acattagtaa gacaaataat agaagaaaaa ataagtggaa ctaaagacac agtagatttt
    30841 gttagaaata aagacattag tggaataact tctataaagt taccaactgt aaaagttagt
    30901 gaatctgata gattagatac agggaatcca agtgatgtag tttacacaaa agatttattt
    30961 acattagagg aaagcccaag attaggttgt ggtatgatgg aaatgaaaga aacaactttt
    31021 gattggactc taaattatga tgaaatagat tatgtaatag atggaacttt agatataata
    31081 atagatggaa gaaaggtttc tgcttcttca ggtgaattaa tattcatacc aaaaggaagt
    31141 aagatacaat tttctgtacc tgattatgct agatttatat atgtaacata tccggcagat
    31201 tgggcatctc aaaattaata aaaatcaagt taagttaata atcaaataaa taatttaaaa
    31261 tacaaactct taaataagca cgcatattta aaaaagctat gaattaaaat tcatagcttt
    31321 ttttataaag aatgttatat tttagacgta ttttttctat atttactggg agatatatta
    31381 tattttttat taaataatct aataaaatgc tctacatttg gataaccaat actattttac
    31441 tgataatctt ttccttatca ctaatcttac attttaaaat attattttta ctcgtaatat
    31501 tatcataaga atttgtttct tatttaaaac taattagaat tataaagttt attgccatgt
    31561 tattaataaa ataaatccag ttaaatcgag tgctagttaa agtaataaga aacttttaca
    31621 atggtttcct ttatcgattg aaataaaagt taatatggta taatatctaa agagagaatc
    31681 ttatcaatta gaatatgcat agaaacaagt ggcttaaaag gagacgttat atggaagaga
    31741 tagtaaagaa ggaacaagca agtatgaatg atattttttt gtatcttaaa gctaaatcaa
    31801 actcattata taaatttgta atattatata atgagtttat caataaacct aaagattatg
    31861 gaactgggga acttataaac atggttgaag tacatatgct aacagcgatt gaagaaaatc
    31921 caggaataag tccaactcag ttagctaaaa tatggaacag aactaaaggt gcaatatctc
    31981 aaactatatc taaattggag aaaaagggtt atataactaa agaaaagaaa gaaggaaatg
    32041 caaaaactat attactatat ccaaccacat caggagtaga gttaagtaag gcacataaac
    32101 tatatgacac catagatgtt acaagaacat ttgaatactt aatcaaggag tgtacattag
    32161 aggagataga tagtttttat aaagtaattg atttgtttat taatttatta gaagaatctc
    32221 cgcaggaaaa taatgattct gaaaaagtgt agctgagatt gaagttgaat aaagagaaat
    32281 agatattata gaagtagtac ttaagtacac attatataaa aatataatag gtataggatt
    32341 aaaaagttta gtggtttaaa gtttaaccac taaacttttt taatgtctat aatctactat
    32401 tatttaattt actaaaaata aaaaaactca ttatattaag atagaaatag aaaaataact
    32461 agaaaaatac tataatatat cagcttaata cagaaaaaag ttaaaaaatt tgagaaaaat
    32521 aaaaatgaaa acgttttata ttgacataga gaaaaagtag tgataccatt taaatatagt
    32581 ttagtagcta aactatattt aaattataat aactatttta gggggatgtt atgaatttaa
    32641 aacaattaag tgaaaaatac gaagaatatg taattcaaat gagaagagaa tttcataagt
    32701 atccagaatt atcttttaaa gaaataagaa caacccaaag aataagggaa gaattacaaa
    32761 aaataggggt cccttttgta tctattgaac caaatatcgt aatagctact atacaaggca
    32821 aaaatgaagg taagacaatt gcaattagag gagatataga tgcgcttcca atgcaagaag
    32881 attcagatgt tgaatacaaa tcagaatatg atggaataat gcattcttgt ggacatgatg
    32941 ctcatggagc tatgttacta ggacttgcac atatgctaaa tgatataaga aaagatttaa
    33001 aaggtagagt attattagtt tttcaagcag ctgaagaagt tggtggtgga cacaaggaga
    33061 taatacagta ctttaaggaa aatggaggac cggatagatt aatagctact catgtttggt
    33121 ccgatattga agctggtaaa atttctgttg aaccaggacc tcgtatggct ggtgggtctg
    33181 gttggagaat agacataaca ggtagaggag gtccagatca aagcatagat cctataaagc
    33241 cagcttgtga tatagtttta aaagtatctt ctataccagt taatcatata agtgtactag
    33301 aacaatgtgt tgtacatgca tgtgcaatac atggaggaac tacaatagga aatgttattc
    33361 caaacaatgc agaggtaata ggtggatata gatattttac tgaagaatca ggcaaaaaag
    33421 tgtttgacat tataaagcaa atgagtaatg gtgttggaca agtttatgga gtggatgtga
    33481 aggttactca tactggaggc ataggacctg ttatcaatga tgaagaagca gttaagatgg
    33541 ctaaagaaat agtttctaat atagatggat tggagttaga ttcttatgag ccaatatgtg
    33601 catcagattg ttatggtgaa atattaaaag agtattctgg cttttattgt tatctagggg
    33661 taggtaacaa agaaaaagga ataatatatg cacaacacca tcctaagtac aatatagatg
    33721 aagatatatt aaagttaggt tgcgaattta tggctaaata tgcagttgaa tttttaaata
    33781 aaaataataa ctaaaataaa tctaatttta taaatggggg gatgaaaatg caaggtgcat
    33841 taaaggaaaa taagaaaaaa agtggtggag gatttttagg atggattgaa aaagttggga
    33901 ataaaatgcc acatcctcta gcattattta catatattac actgatagta gtagcattat
    33961 ctgcaatagc aagcttttta ggtttttcag caacaagtcc tgctacagga aagttaataa
    34021 aagttatgaa cttaataagt gcaaaaggtt tagtactatt tatgcaagag tttgttaaga
    34081 acttccaaaa cttccctgtg cttggagtag ttttagttat ggcagttgcc acaggagttt
    34141 gtgaaaagac aggatttttt tcaactgcca taaaaatgag tttatcaaaa gttaagggga
    34201 atgcggttgt atttataata gcttttatag gagtatttgc taatcaagct ggtgatgctg
    34261 cttttgtatt agtaccaact cttgcaggag caatatttta tggattaaat agaaatccat
    34321 tagctggtat attctgtgga tttgcatcag ttggtggtgg atttgcaaca gctgtaattc
    34381 ctgggggatg ggacgttacg ctaacgccaa taactgtatc agctgctcaa actattcaac
    34441 ctgcatttga tatgacatta ttagctagtt attatgcact atttgtatct gcgtttatag
    34501 tagctacagt atcaacaata gtaacggtta aatttataga acctaaatta ggtaagtata
    34561 ctggtaaacc agaaggtata gatgataatc aaggttttga ggtcacaaaa gaacaagcaa
    34621 aagcagcaaa gttagcaggt tttacagttt tagcttatgt agcgttatta attgctttgt
    34681 gtataccagc taatagtttt ttaagaagtc cagaaggttc tttaatattt ggagcaccac
    34741 ttatgtcttg cttacagttt tttatagtaa tactattctt cttgccaggg attgtgtatg
    34801 gaatgagggt tggtaaaatc aagactgtaa aagacttaaa tgatatatta tgtcaatcaa
    34861 tggcagcaat ggcaccgttt atcgtacttg caatagttat aggtcaattc ttaacgctat
    34921 tctcagtgtc taatttagca caggtactag ctataaaagg tggagcatta ctcaactcat
    34981 tgccactacc accacaagct ataatactgc tattcttagt actagtagcg tttataaata
    35041 tatttgttat aagcggaagt acaaaatgga tgatatttgg accagtattt gttccaatgt
    35101 taatgcaatt aaacatacat ccagcattta ctcagtttgt atatagatta ggagattctg
    35161 taaccaatca tttatcacca ttaaatgcat tctttataat acttttagca acagtccaaa
    35221 aatacgataa aaatgcaggt atgggaacta tattctcagc tatgatacct tacactatag
    35281 gttactttgt agtacttgca gttttagtag tagtttggat gacaataggt ataccagtag
    35341 gaataggtgg acaagtttgg ttataaaaca tatttaataa ttttgggagg aaaaaaaatg
    35401 gaaacaactg aaataagata caattttgat gaagtaatag atagaagtgg aacaaactgt
    35461 cttaaatatg atcttaagag tcaatttatg ccagaatctc cagaagatgc actaccacta
    35521 tgggtagcag atatggattt tgcatgtgcc cctgagataa ttaatgcaat gcatgaaaga
    35581 atagacagaa aaatatttgg atatagctct caacaaactg atgattatta tgaagctgta
    35641 tgtggatggt ttaagagaag atttgattgg aaaatagaaa aagagaatat attctttagc
    35701 ccaggggttg tgcctgcgtt aggatttttc acacaaatat taacacaaaa gggtgatggt
    35761 atcataatag aaaagcctgt atactatcct tttgaagata aaataactaa caatgaaaga
    35821 aaagtagtta atagtccttt aaagtttgaa gatggtcatt attctatgga ttatgatgga
    35881 tttgaagaat tagctaaaga tgaaaataat aaggtgttta tattatgtag tcctcataat
    35941 ccagttggta gagtatggaa aaaagaagag cttagaaaaa tagtagacat atgtaagaaa
    36001 tatgatttgt ggataatatc tgatgaaata cattgtgata ttattcgtaa aggtgaaaag
    36061 catataccat tagaagtagc atgtcctgat tataaagata gaataataac ttgtacagct
    36121 ccaagtaaga gttttaactt agctggtatg caattatcaa atatagtaat caataataag
    36181 gaattacaag aaaaatggat gcttgaaaca gattctaaat tagctatatt cctacctaat
    36241 ccattcgcaa tagttgctac taaagttgct tataatgatt gtgaagattg gatgaatcaa
    36301 gtaaatgagt atatagatgg taatattaaa tatgtagaag attttgttaa tgagtatatg
    36361 cctaaagtaa agataataaa atctcaagga acttacttag tttggttaga ctttagaggg
    36421 tatggattag atgcaaaaca gcttgaatat gtaatgctta acaaggcgaa ggtattgcta
    36481 gatgaaggat acatattcgg agaagaagga gcaggatttg aaagaataaa tgttgcttca
    36541 cctagaacaa ttatagaaga gtgtatgaat agaataaaat gtgcatttga aggattataa
    36601 tagtaatatc taaataatat atttgtgtat tttaaaaaaa gactatgcta aaaaaatatt
    36661 tcaaagcata gtcttttaaa gttttatgat gagtttaaaa aatttcaaaa cgttactatt
    36721 cacttatatg tttatattag aaataattcc acaatatact cattttctaa agttgcactt
    36781 ttatacacct tgcttcacca atatcatgtg taaccaaaat agtagactta ttctcattct
    36841 taataatact ataaacatca tcacaaacta ataatctagt ctgataatca agagctgaaa
    36901 aaggttcatc taaaagtaga atatctggat ttacagaaag tgttctaata agcgcaactc
    36961 tttgtctcat acctccagat aattcttttg gatacatact tctaaaatcc cataatccat
    37021 aagtctttaa aaggctttca actctatcta aagatttttt atcttttttg ccttgaattt
    37081 ccaatccaat agttatatta tccattatat ttctccattc aagcaaatta tctttttgaa
    37141 acatatatcc aatatttcca gtaatcttta tatcaccact agttggtttt aaaagattag
    37201 taagaatatt taatattgta gatttaccac ttccagaagg accaagcaaa gttaatattt
    37261 ctccttcttt caagttaaaa ttgacatcct ttaatacttc aagctcgcct tccttagtgt
    37321 agaagttcat atttatattt ttaacttcta ctatgttgtc attcattatg ccacccccta
    37381 taacttttag ctcgtatata ttatgttatt aacaatatga cctatttgta ccatttttca
    37441 taaatataat ataaatattt tgtttattta cgtattttct tagtaacttg tacgtataaa
    37501 ttatagataa ataaattata aggtagggga taaatttgag taacataata acgaatttaa
    37561 tagagtcaat atttactaat ccaataacta tattgttttt acttgcaata actgtgtatt
    37621 ctgtttttaa aataatagaa aataacagag tatattcatt tgtaagttca aaattagacg
    37681 aaatcaatag agactataag acaagtgagt tttataaaaa ggtaagggat gactactata
    37741 catatagtaa agaaaatcct tatgcagacg taaatataac ttcatttata gaggaagttg
    37801 tatctgattt aaagcataat aatttgccat tgttagaaaa aattagaagt ataaaaaatt
    37861 catcttcaat aagtatatta cttggggttt taggtacgtt tgttggtctt tctacaatgc
    37921 ttttatgtgt tgatactaaa gacattataa attcacttcc ttcaactatt agtagtatgc
    37981 aaactgcatt tacaactagt atatttggag ttgtattttc tctaattata ggttatttta
    38041 ctaagataaa agattgtgaa catgttttga tacaaataat gttaaaatct gaaaatttac
    38101 taacatctga aataactcat tttaagtcag aaagaatgga tttaaaagta gaagaggtaa
    38161 aaaatacaat aaaacaaata agtaagtcta tagaagctat tgaaaaattt gataaaatat
    38221 ctaaagattt aaatgacttt aatgatgaat ttatcagtgg tatagaagct t
//
LOCUS       DAEPHU010000039        36923 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 01A10CD0081
            SAMN05941466-rid12468953.denovo.039, whole genome shotgun sequence.
ACCESSION   DAEPHU010000039 DAEPHU010000000
VERSION     DAEPHU010000039.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941466
            Sequence Read Archive: SRR6291087
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 36923)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 36923)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068158.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 22:43:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,892
            CDSs (total)                      :: 3,805
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 87
            rRNAs                             :: 8, 1, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 55
            CDSs (without protein)            :: 55
            Pseudo Genes (ambiguous residues) :: 0 of 55
            Pseudo Genes (frameshifted)       :: 21 of 55
            Pseudo Genes (incomplete)         :: 28 of 55
            Pseudo Genes (internal stop)      :: 16 of 55
            Pseudo Genes (multiple problems)  :: 8 of 55
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..36923
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941466-rid12468953.denovo.039"
                     /strain="01A10CD0081"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            227..1855
                     /gene="aspD"
                     /locus_tag="KR231_002056"
     CDS             227..1855
                     /gene="aspD"
                     /locus_tag="KR231_002056"
                     /EC_number="4.1.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate 4-decarboxylase"
                     /protein_id="HBH0004428.1"
                     /translation="MKNHTYKEIKNIYGKISPFEFKDKLIDIAKYTAKENNRELLDAG
                     RGNPNWTCSTAREAFFTFGHFAITETRSNWDLGHLAGMPQKKGIKERFFKFINENIDM
                     PGAYLARDIINFGINELGFDGDEFVHELADGIIGDNYPLPDRMLPHMEKIVHDYLVQE
                     MKYDISGKYGDVEIFAVEGATAAMCYIFDSLMANELLKKGDTIALMTPIFTPYLEIPN
                     LPRYDFKVVNINANEVDEKGAHTWQYTKKELEKLRDKSIKALFVVNPNNPASIAMDET
                     SCNNLIDVIENYNKDLMIISDDVYGTFVEDFSSLMSKLPYNTVGVYSYSKYFGVTGWR
                     LGTFALHKKNVFDKKINDLTGELKKSVDKRYSDMSLNPSSLSFMERVVADSRLVALNH
                     TAGLSTPQQVQMAFFSAFALIDKVDAYKKLNMSICHRRQKLLFEALELPINENKNNAA
                     YYTQFDIEEWAKLNYGEDLFKFISKTASPVDVLYKLANDYSVVLLSGNGFYGPEWSIR
                     ISLANLYDEAYTKIGKAIREILNGYIVEWQKIKK"
     gene            1976..2971
                     /locus_tag="KR231_002057"
     CDS             1976..2971
                     /locus_tag="KR231_002057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparaginase"
                     /protein_id="HBH0004429.1"
                     /translation="MSIKKKVAIVFTGGTISMTVDDKVGAAIPTLSGEQILSMVTNID
                     KVADVEVFNFDEIPGPHITPYRMMELKNYVNDLLARKDITGVVITHGTDSLEETAYFL
                     DLTIDNIKPVIVTGAMRSSSELGYDGSSNLSASVCTAVSKDAMGKGVLVVLNNEVLLA
                     SEATKTNTLSLNTFKSLTSGPLGIIDCNELVLTRDIVNRTIIDTDKVESKVALFKAYV
                     GENADFIRFAVDSGYKGIVIEAMGRGNIPPQMLSGVEYAREKGLPVVIVSRCHSGRVF
                     DSYGYFGSGRDLKNLGCIFGGDLPGQKARIKLILALGKTDNLDEIKDFFEKGIYC"
     gene            complement(3160..3543)
                     /locus_tag="KR231_002058"
                     /pseudo
     CDS             complement(3160..3543)
                     /locus_tag="KR231_002058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431032.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
     regulatory      3769..3866
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01051"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="cyclic di-GMP riboswitch class I; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="cyclic di-GMP"
                     /db_xref="RFAM:RF01051"
     repeat_region   4008..4365
                     /inference="COORDINATES: alignment:crt:1.2"
                     /inference="COORDINATES: alignment:pilercr:v1.02"
                     /rpt_family="CRISPR"
                     /rpt_type=direct
                     /rpt_unit_range=4008..4036
                     /rpt_unit_seq="atttacattccatatagttaatataaaac"
     gene            complement(4651..4809)
                     /locus_tag="KR231_002059"
     CDS             complement(4651..4809)
                     /locus_tag="KR231_002059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0004430.1"
                     /translation="MDNFLQGILASLSASLIVYIASKLFRKRKKPLKAATKSGWEFDL
                     KIRFHKTK"
     gene            complement(5168..6538)
                     /locus_tag="KR231_002060"
     CDS             complement(5168..6538)
                     /locus_tag="KR231_002060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp29"
                     /protein_id="HBH0004431.1"
                     /translation="MKLKKLLSLGLAVSMFAAGPISANALDTIYTIQGKDKYETAALI
                     ADEQNYTTAILINADSTMADGLSASGLAGATNAPIFLTKKNNIPNATLKRVEKAKKVY
                     IIGGESSIDKATETLLKDKGIEAKRLQGSDRIKTSYNVAKEINSINKVNKVILTNAFK
                     GEPDAMSAAPVAVRDKAAIVLTDGKSVPFNTTGVESYVIGGTSSMSDKLVNDTNSTRL
                     GGVDRYDTNKKIVNKFYNGAKEFYIASGTDLVYALVASPMAKNNPIVLVDIGSNKDIL
                     KNAAKVTGIGNLSDKIMLECENTINNISLPSSNKNIICGLKIDFDSKHIIWQDKGSYL
                     ECYDDNLEYYTEKYKDPTVPINIENTSTQNLDVTKLKVYGEANSTLYMGQYAKIKMDF
                     NSFGVLKPGEKCTIYLDIISLDPSRSMTLTFSYVGDKENYKYEQGLASRILFYNPDGE
                     DFFEYK"
     gene            6821..6919
                     /locus_tag="KR231_002061"
                     /pseudo
     CDS             6821..6919
                     /locus_tag="KR231_002061"
                     /inference="COORDINATES: protein motif:HMM:NF026008.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="Arm DNA-binding domain-containing protein"
     gene            6938..7359
                     /locus_tag="KR231_002062"
                     /pseudo
     CDS             6938..7359
                     /locus_tag="KR231_002062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431042.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            7590..7862
                     /locus_tag="KR231_002063"
     CDS             7590..7862
                     /locus_tag="KR231_002063"
                     /inference="COORDINATES: protein motif:HMM:NF012798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HBH0004432.1"
                     /translation="MSKHQFKSVSTFFTKKNVSQFYKKNNLKKIRIHDLRYTSATLLL
                     LGGTNMKVVSERLGHTDIKITMNRYSHVLKEMDKEASDNLSELLFK"
     gene            complement(8180..8848)
                     /locus_tag="KR231_002064"
     CDS             complement(8180..8848)
                     /locus_tag="KR231_002064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HBH0004433.1"
                     /translation="METVTNNQSGVEIQLSLFEAIKDLLLINPIFLLGIILIGIFLVV
                     IFKKNSDIPKVKTSILSLAMYYYLCLTLSHIVGIPTFGEYIRLSQLGETFFNPNINLI
                     PFSDGFSLSFILNILLFVPLGFLCPLISKTFERLRNTFLIGFGLSLFIETIQLFTLHR
                     ATDIDDLLTNVIGTIIGYFCFKLIAKLRIVKLHSDDDSMEQDYTVCIPIAIIIVALIL
                     GFFS"
     gene            complement(9684..12104)
                     /locus_tag="KR231_002065"
     CDS             complement(9684..12104)
                     /locus_tag="KR231_002065"
                     /EC_number="6.1.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="leucine--tRNA ligase"
                     /protein_id="HBH0004434.1"
                     /translation="MSVYNFKEVESKWQKIWKDNNQYKMDTAQTEKPNYYTLEMFPYP
                     SGKIHMGHVRNYSIGDVVARFKKMEGYNVLHPMGWDSFGLPAENAAIKHGIHPHKWTM
                     ENIEEMKEQLNLLGISYDWDKEVATSTPEYYRFTQEIFLKFLEHGLAYKKKSYVNWCP
                     SCETVLANEQVVQGACERCKATVLKKDLEQWYFKTTEFAEELLNDLDTLDGWPEKVKT
                     MQKNWIGKSTGADLVFDIDGTDKSMTVFTTRPDTTYGVTYMVLAPEHELVKELVAGTE
                     YEADVEAFVQKMHTMTEIERTAADVEKEGMFIGRYVINPLNGKKVPLWIANYVLVEYG
                     TGAIMAVPAHDERDRDFAEKYNLDIIDVITEDNKMINSEEFNGLDASEGFEGIIDKLE
                     KEGRGKRTINYRLRDWLVSRQRYWGCPIPVVYCDECGIVPVKKEDLPVLLPTDVEFTG
                     KGESPLTTSKQFMSTTCPHCGKPARREVDTMDTFVDSSWYFLRYVDSNNENEPFSKEL
                     VNRWHPVDQYIGGVEHAIMHLLYARWFVKAFKSMGMVDFNEPFKNLLTQGMVLMDGSK
                     MSKSKGNTVSPMDIIDEYGADTARLFVLFAAPPERDLDWSEQGVDGCFRFLNRVYRLV
                     DELADVVKKDVEFGELNSQDKDMRYTIHSTLKKVTADLSEKFGFNTAISALMELINDM
                     YKYKELDNINEAVIKEGVQTIVTIIAPFAPHLGEELWTMIGKEGSVFDIDWPKYDEKA
                     LVKDEIEVVVQVNGKVRGKLTVNSNISKDEMEKVALEDEKIKGLVEGKTIVKVVAVPK
                     KLVNIVVK"
     gene            complement(12458..12808)
                     /gene="rsfS"
                     /locus_tag="KR231_002066"
     CDS             complement(12458..12808)
                     /gene="rsfS"
                     /locus_tag="KR231_002066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome silencing factor"
                     /protein_id="HBH0004435.1"
                     /translation="MTVEQMTKIAYDAIEDKLGQDTVIINIGKVSSLCDYFIITTASS
                     QRQVKAIADNVEDELAKLGLEPRGKEGQGTQTWVLLDYGDIMVHVFNEENRGFYNLEK
                     LWKDAPYIDIDTLA"
     gene            complement(12925..13497)
                     /gene="yqeK"
                     /locus_tag="KR231_002067"
     CDS             complement(12925..13497)
                     /gene="yqeK"
                     /locus_tag="KR231_002067"
                     /EC_number="3.6.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bis(5'-nucleosyl)-tetraphosphatase (symmetrical)
                     YqeK"
                     /protein_id="HBH0004436.1"
                     /translation="MNLENINQRLNQMLPVGRLSHSKNVAKCAEKLCEIYGCDKEKAY
                     LAGMIHDCAKYLSDKEIEDYVNKYEIYLDPIEDGNRSLSHSVIGAYICEYEFEVEDED
                     IINAIKYHTTGREDMSLLEKIIYIADLIEEGRKFPVVDTLRELAYGGKLDEALLTSFN
                     NTLMFVINKKEEIHPRTVMARNYLIKEKLL"
     gene            complement(13498..14187)
                     /locus_tag="KR231_002068"
     CDS             complement(13498..14187)
                     /locus_tag="KR231_002068"
                     /EC_number="2.7.7.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate-nucleotide adenylyltransferase"
                     /protein_id="HBH0004437.1"
                     /translation="MRSENLVKMAELKNTEKLEKFNRHKGKIKIGILGGTFDPIHYAH
                     LATAEFIRDKYDIDKIIFIPSGNPPHKLCITTDKYDRYNMTLLATESNEDFLVSKVEI
                     ERKKRTYTIDTLKYLKKKYKNADIYFITGADAICSVEEWKDVKKNFELATFIAATRPG
                     ISLLRSQETIEKLTKKYNADIITVYVPSLDISSTYIREQLNEGKSIRYLVPENVENYL
                     YENKLYQYGDD"
     gene            14463..15101
                     /gene="recX"
                     /locus_tag="KR231_002069"
     CDS             14463..15101
                     /gene="recX"
                     /locus_tag="KR231_002069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination regulator RecX"
                     /protein_id="HBH0004438.1"
                     /translation="MGIITKIEQQKRNDDRVNIYVDDKFFIAIFKELVYTFNLKKGNE
                     INEEELKPILDDEMYIKAKNKALNILSHADQSEKKLKEKLSSEFDENIIERVIDFLKS
                     YNLVNDSVLAQKIVNTNVNLNKCGKNRIKQNLYNKGINRSTINEAVSELDKDTEFENA
                     MYLAKKRYERVKKEDKKKIYQKISQHLSYKGFDYDIIKRVLNKLLNFDEYDI"
     gene            15254..17257
                     /locus_tag="KR231_002070"
     CDS             15254..17257
                     /locus_tag="KR231_002070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha amylase C-terminal domain-containing
                     protein"
                     /protein_id="HBH0004439.1"
                     /translation="MKSQKRFKILDIDVYLQPFESDIKKRMKHYENMKSKTLKNYKDF
                     SSFANAHLYYGFHQTNDGFFYREWAPNADSLSLIGDFNNWNRKSHPLRKIGSGNWEIF
                     IPGQNSLPHKSEVKVQVTANGKTFDRIPLYIKRVIQKDFGGFNGQIWQPKTPFIWTDN
                     DFDLKNITYPLIYECHIGMSTESESIGTYNEFTEKILPKIKKAGYNTIQLMAIMEHPY
                     YASFGYQVSNFYAISSRFGTPEDLKNLINTAHSMGIAVLLDLVHSHAVKNTLEGINEF
                     DGSEHQFFHSGSKGNHPAWGTKLFNYGKPEVIHFLLSNIKFWLNEYHFDGFRFDGVTS
                     MLYHNHGLGVSFDSYEKYFSMNTDIEAITYLQFANELIKEIKPNSISIAEDMSGMPGM
                     CIPIKDGGIGFDYRLAMGVPDFWIKTISNLSDEDWDLGKMWYELTTRRPGEKNIGYCE
                     SHDQALVGDKTIIFWLADKEMYWNMEINSNNHVINRAISLIKLIKLITFSLAGEGYLN
                     FMGNEFGHPEWIDFPREGNNWSYKYARRQWSLSEDNNLKYKQLLNFDKSMLELTKYSD
                     IFIQNSHELIHMDNDKKILVYSKGKYLFIFNFHPNLIQSVDISKFQNTNYKTILNTDM
                     VEFGGNTKKENLRDYDVYFSSTPPSSKMPIASRTAIVLLDSSI"
     gene            complement(17384..17695)
                     /locus_tag="KR231_002071"
     CDS             complement(17384..17695)
                     /locus_tag="KR231_002071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antibiotic biosynthesis monooxygenase"
                     /protein_id="HBH0004440.1"
                     /translation="MKIITEIVEFNVEENLSKEEFIEIVNDLELKFHSIQSGFIDTEL
                     LYDEKSQKWIMIQHWESIEDLKSASSKMFKDSSTEKFRKALKNQTVKMNIIPQIKSWK
                     L"
     gene            complement(17773..18591)
                     /locus_tag="KR231_002072"
     CDS             complement(17773..18591)
                     /locus_tag="KR231_002072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HBH0004441.1"
                     /translation="MLSVTRYSIKNVRLKPWVKFIWYFETKSNILLNNKLLPTDSIDI
                     ILNLSDVMEYKIENQDYTASNMHFNGIRDKHGFIIQHGNIRVIGISFYPFGLYPFLKI
                     PISEFNRQIVDLEAVSQLFAKKLEESLNPTQSVEKIVLYLEEVLLSILEEDLISNKYV
                     KLLNSFIYVNRYSNIKAFCDDTNINIKTLERICLKYTGYTPKILKRIYRFKMASNQLI
                     YNYKDDELFDFIYENEYYDQAHFIKEFKKFSGTSPIKFIGENKTIKENIKYSYL"
     gene            complement(18691..19215)
                     /locus_tag="KR231_002073"
     CDS             complement(18691..19215)
                     /locus_tag="KR231_002073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HBH0004442.1"
                     /translation="MEVTAKQKFTTKDMVETSLLIALVFIATKFINIRLPISINGGLV
                     HLGTAMLFISAIVFGGKKGALSGAIGMSLFDLISGWTLWAPFTFIVRGVMGYLLGKIA
                     WANGNNGNNFLINVIGICVSSIWMLFGYYVTEVILYGNFIVPLTSIPGNLMQVLIGLI
                     IALPISKVLKKCIK"
     gene            complement(19234..20376)
                     /locus_tag="KR231_002074"
     CDS             complement(19234..20376)
                     /locus_tag="KR231_002074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine--glyoxylate aminotransferase family
                     protein"
                     /protein_id="HBH0004443.1"
                     /translation="MNKKINYAPGPTETRENVRLARAEKTTNPDIDIDFVEFYKKTCE
                     KFGNIIGTKNDVYILSGEGILGLEAACASLTEKGDRVLVIDNGIYGEGFKDFVTMYGG
                     EYVLFSSEYTKSIDIDELKAFLDEDSNFKYATVVHCDTPTGVLNDVSKICPLLKKYGI
                     LTVVDSVAGMVGERLSVDESKIDIILGGSQKAISAPAGLTIVGISQDAKNCIKNRKTD
                     VIGFYCNLNIWEGYYEKKYFPYTMPISDIMGLDKALDNILEEGIENVLNRHEKIAYSV
                     RKSIEEYGLELFLEEGYSNTVTAIKIPESIGALELTDYMLKNYNTLVATSLNQYMDTI
                     LRIGHMGENANLNKIEHVLNVLDKSLSALGFKGNGNLLNLFNKYYF"
     gene            complement(20656..23043)
                     /locus_tag="KR231_002075"
     CDS             complement(20656..23043)
                     /locus_tag="KR231_002075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HBH0004444.1"
                     /translation="MINTTKIAKSNLKQNKSKSILIIITIILSTLMLSSIGIYIVDAG
                     AYQKENTIKYSGNYQGILANVDEKQADILSNHADVELTGEMNGVGVEKLEDDSNISLA
                     YMNEDALKLNSFEFIKGKLPSKENEIVLDSGALKALGYKNKDLGEKIKISYDDYKNDK
                     KIEKEFIISGILKTSEISEAGKYYYAIISESYMRNTRDMSQEDFNIYVKFNDKSNLSI
                     EQAKEKLDKIANDIGLDTINTAVNENYINALKPDMETIMGGVFVGLVIVLSSILVIYN
                     IFYISIVTKVQEFGKLRAIGATKKQIKNIVFKEGFILAGIAIPIGIILGYVLANIIIK
                     SFMDIDVKSSRLPVILSVVVISFISVVLSLLKPMKVASKVSIVDAVRYTGNKISNKSK
                     RKGYKNINLKRLSHANLERNKKRTYMTLASLILSGTIFITVSTALESFDAEKMAREHF
                     PYDIEVRLSGYEMNSDKNPKDNLNILQMDNPLSKDFFNQIKNMEGIKRIESARSVKIG
                     MEDYDVEFKYDLLQSINENDVKSLNKNIIDGKINLERLQTGDEIVITHVDTAKEMGVK
                     AGDKIRLTLYDGDKKIKKEFKVQAIAMGVPSFGIGKDFIDRTLKYDSTSSLGIYTEEG
                     KYQEIKDSIKKIAKNNGFLETDFIDSRIESNKATISFIKIMGYTLTGIIGVIGFMNLV
                     NTMITSIVTRKKELGMLQAIGLTNKQLVKMLNSEAIYYTSGMMIGSILFGGILGYIAV
                     IFLKKTGLSYATYSLPIVPILLMIVCILIAQFITTYLIGRSFNKESLIDRVRYSE"
     gene            complement(23036..23719)
                     /locus_tag="KR231_002076"
     CDS             complement(23036..23719)
                     /locus_tag="KR231_002076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH0004445.1"
                     /translation="MKILYTENLSKHYGKGESLVRALDNVDLEINEGEFVAIIGKSGS
                     GKSTLLHMIGGLDIPTSGKVYIDNKNIFTLKEEELAVFRRRKIGFIFQSYNLIPSLNV
                     WENVVLPIGLDGREVDESFIKELLKSLGLENKHDVLPNTLSGGQQQRVAIARALATRP
                     AIILADEPTGNLDSKTSDEVMSILKSMSKKYSQTLVMITHDDSIAQMADRVIFIEDGR
                     VSKVGDKND"
     gene            complement(23836..25146)
                     /locus_tag="KR231_002077"
                     /pseudo
     CDS             complement(23836..25146)
                     /locus_tag="KR231_002077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431070.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
     gene            complement(25140..25847)
                     /locus_tag="KR231_002078"
     CDS             complement(25140..25847)
                     /locus_tag="KR231_002078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBH0004446.1"
                     /translation="MNNILLLEDDKSLNRGISFKLKKEGYNVFSAFGIEEAKNIFAKE
                     EICLIISDIGLPDGSGFDFCEEIRKKSDVYIIMLTALDEEVDIVTGYDLGADDYITKP
                     FSLMVLISKVNALMKRVNTVKNYTLLVCDDLFFYYIENKLIIRTDDKEEEIILSKTET
                     KLLKYLMENSMQTLTKEQLLESLWDSSGNFVDDNTIAVNIRRLRQKVEKNPSEPKYIK
                     TVRGVGYMWGERSIKKC"
     gene            complement(26152..27993)
                     /locus_tag="KR231_002079"
     CDS             complement(26152..27993)
                     /locus_tag="KR231_002079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729380.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5'-nucleotidase C-terminal domain-containing
                     protein"
                     /protein_id="HBH0004447.1"
                     /translation="MKIRRYLILVIIILITTSQSFISYGLERFEEITIFHTNDIHGRY
                     AEGDDHIQIGNLATLKKETPNSILVDAGDCLHGLPIVNMDRGKSAIELIKCAGYDYIT
                     PGNHDFNYGKDRLFELSKSANLGENTLKFLSSNIFENGKKVFDSNDIKEIDGIKIGFF
                     GLSTQETKSKTGFKNVEGLEFKNPIESATEQVNELKGKGANVIVAICHIGTNSLSKPN
                     SIDIANEVQGIDLIIDGHSHTKFENGKQVGDTLIVSAGQYLENIGEIKLTLDTNDVEN
                     IKIENKSVRLIGKEEALKYKLDSAVSKKVDEIKEQQEKILDKVIGVTTNTLDGSYENV
                     RTKETNLGNLISDILLDKTKADISLFNGGNIRDTIEKGNITRRDIVDVFPFSNTIVTK
                     ELTGAQIKDVLEHGVKLYPEKSSAFLQVGGISYYFNPKQKEGEKITNIQKEGKPLDLN
                     KKYVVATNDYIASGGDEFPCFSKEPVLKEFGNLESAVIEYIEYKKEISKNVDGRIGIK
                     SKDELISKNHESDLILSENEKNINDNEENLSNNIKSSDSDKNKSLDKTSARESSNLGI
                     SKREAKEKSPKTGDLGFSNSIIIFIVSSTLICLLNFNQKELKDKKSK"
     gene            complement(28206..29090)
                     /locus_tag="KR231_002080"
     CDS             complement(28206..29090)
                     /locus_tag="KR231_002080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4846 domain-containing protein"
                     /protein_id="HBH0004448.1"
                     /translation="MKVLKKITILSLITLTLVGCSNGEDKKVVEGSKKIQNSKKDEQP
                     IIVHKDANILKDRYEPPKGFKRVDVEKGSFESFLRNTKLKNYGEKVKYYDGRTKESKG
                     IYDSVFDVDIGNRDLHQCADAIMLMRAEYLYQNKLYDEISFDFVDGFKAKYSKWAQGY
                     RISVKDSGSSWYKATEYSTSYESFRKFMDIVFAYSGTLSLEKELEPVKVEDMKIGDVF
                     IVGGSPGHASIIMDMAENEKTGEKVFMIAQSYMPAQQTQLLINRKNPNLSPWYSLDFE
                     GDLTIPQWTFKRDQLKRF"
     gene            29298..30215
                     /locus_tag="KR231_002081"
     CDS             29298..30215
                     /locus_tag="KR231_002081"
                     /EC_number="3.1.26.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011969064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Z"
                     /protein_id="HBH0004449.1"
                     /translation="MIDLTLLGCGGNVPMPNRFLSSVFINYKGRKILIDCGEGTQVSM
                     KLKKCGFKDIDLICITHLHGDHIFGLLGLLSTIGNSGRTSDLTIVGPVGIVDCIRSMR
                     NLVEYVPYTLKIIENPQGNFSLDNKVLRNLEISTISLEHSIECLGYSFNFRRNPKFDI
                     DKATKNEVPKILWNKLQEGQNIVLDSKQYTPDMVLGELRKGVKISLTTDTRPIESIPD
                     FIKDSDLFICEAMYGDDLDISKAVRNKHMTFREAANLAKLGNVKQLLLTHFSPSLDIP
                     SMYLENATNVFENTILGEDRLSLRLNFDE"
     gene            complement(30357..31691)
                     /locus_tag="KR231_002082"
     CDS             complement(30357..31691)
                     /locus_tag="KR231_002082"
                     /EC_number="1.8.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA-disulfide reductase"
                     /protein_id="HBH0004450.1"
                     /translation="MRVIIIGGVAAGMSAAAKLKRIKPEYEVVVYEKTEIVSFGACGL
                     PYFVGGFFNDADELLARTPEKLREAGIDLNIFREVVEVDSESKKIKVKNIKTDEIYED
                     YYDKLMIATGARSIMPPIKNIKLKNVSTLKSLYDGEYLKKLLSNEDNKRVTIIGAGFI
                     GLEAVEACKKLGKDVDVIQLEDRILPQVFDKEMTDVLEEEINRHNVNLHLDEMVVELC
                     GEDKVEKVITNKGEIDTDVVIIATGVRPNTEFLSNTNIKMLKNGAIVVDEYGRTSVED
                     IYSAGDCATIKNIVSNENVYVPLATGANKLGRIVGENLAGREVSYQGSLSSSCIKIMD
                     MEAASTGITEKQAKDLGINVKSKFISDYNQTHYYPGRNKIYVKLIYDADTKVILGGQV
                     AGFKDAVQRANVLAAAIFGKMTTNQLGMLDLCYAPPFARTWDVLNVAGNVSK"
     gene            32032..33420
                     /locus_tag="KR231_002083"
     CDS             32032..33420
                     /locus_tag="KR231_002083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation:dicarboxylase symporter family
                     transporter"
                     /protein_id="HBH0004451.1"
                     /translation="MESSFLSQFLMITDFKTIFFIILLLGTFFIVRQFEKKKIKFSLR
                     TIYATVLGLILGIIIQAFAGFPNDTTQVTWLQEVSKWYSLFGSGFMDLLKMLVVPLVF
                     LSIIKVIINMKDNNLGTLTFKSLGMLLATTAIAAIVGIIVANIMKLGVGANMPTLVEN
                     QELKEINSLVDTLRGLLPSNPVMAMANGNIVATIIFATFIATSIKRLSKKHFETIKPF
                     IDFIEASYKIIVSVSMTVIKFMPYAVVALLANTITSQGISSIVSVLQFILALYISVAI
                     LFIIHLIFITLNGLNPITYIKNSTEALLLAFTSRSSLGTLPVTIESLVQNHGVDEGVS
                     SFTASLGANMGMNGCAGIYPALMAVTLANMAGVNMDMSFYVMLLIVITISSFGIAGLP
                     GTATMAVSVVISGVGLGSYFPLVGGILAIDPILDMGRTMINVNGAMVSSITVGKSLGK
                     IDKEVFSKKNIS"
     gene            complement(33494..34702)
                     /locus_tag="KR231_002084"
     CDS             complement(33494..34702)
                     /locus_tag="KR231_002084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0004452.1"
                     /translation="MNRFFKVRLITAIMFLIILFAFSIFNVCYSGKDTIQEIKNSIAE
                     KSSLKDTISSIDNTVNDKVIYKNTFIETYGYLQKLMGKNEFSKFSVVKDTSGKMHYTY
                     FAKAPNPVGVIADRVRKFSDEMEKQNTKLVYLMTPDKYIKGVTKFPKGIPYSYSNETA
                     DNFLNQLKKYNVDYIDFRENILKSGIPKDDLFFKTDHHWKVETSFWAFGELVEQLNKK
                     YNMNLDENHYYRDKDNYNSIVYPKSFLGSMGRKTGILYGGIDDFTLIYPKFKTNYTYY
                     TDSKSQKFELKGRFEESLILSYPFNADLDLMDGQSDKYFTYLLGNRPLVKIKNIENPD
                     GLKVLFVKDSLIVPTAAFFSSVCSSIDMIDPRYYDGDILEYAKSHDYDFVFISVYPQN
                     LTKEFFPFCE"
     gene            complement(34717..36135)
                     /locus_tag="KR231_002085"
     CDS             complement(34717..36135)
                     /locus_tag="KR231_002085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBOAT family protein"
                     /protein_id="HBH0004453.1"
                     /translation="MLFSSLIFLFYFLPITLVLYYVFRFNRTIQNMILLAVSLFFYAW
                     GEPKFVVIMIVSIIMNYIFGLLVDRYRESKIKVKVFLVLMCAYNIGVLFIFKYLAFAL
                     RNISELISTELTIPNIILPIGISFFTFQGMSYVIDVYRRHGEVQKNPFYVGLYIAFFP
                     QLIAGPIVRYESVAEQILNRKETWNKFSIGTCRFITGLGKKVLISNNMAIVADYIYTM
                     NSQGEIAASLAWLGSIAYTLQIFFDFSAYSDMAIGLGLMFGFKFEENFNYPYISKSIS
                     EFWRRWHISLGMWFKSYIYFPLGGSRVANKDIMIRNMFIVWLFTGIWHGAEWTFVIWG
                     ILNFVFLIIERFIMFEKIENHNFIKHIYALLVVNFGWVLFRSPNLKEAYNYFKAMFGG
                     NGAIWSDYTYMFLKEYWVFFIFAFIFSVPIAKKINKFVVEQAKYSMIFNVFYPISAIL
                     LFFISVTYLVTGSYNPFIYFNF"
     gene            complement(36153..>36923)
                     /locus_tag="KR231_002086"
     CDS             complement(36153..>36923)
                     /locus_tag="KR231_002086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0004454.1"
                     /translation="INLSIQSKNMLEFRLKEGSEVFLEGKNIIYSDKIKEGCIEVPGE
                     FEGKIYVNFNSLINEESNVVLDSNMLSNIVSWGITFIPSDEEHNIVIIKKISLLSEEK
                     LRFLNNIKIIGDEEVQIPVLGQSISQYEVLGLKSDSKIKYSLMGKQDNVSISQNGKLT
                     LSNKAKPGQIILQVNVDDKFKIGKKITLTESWSINKKDKDGVPYTLVSPEQSPTVQDM
                     KKINFMNNIITFVRILFVSLVIICFGIYLYWKKCSKTK"
BASE COUNT        12500 a         5984 c         4301 g        14138 t
ORIGIN      
        1 aactaaggtg ataattaaat tgaatattta ttttatataa caatcatttt ttattaaaag
       61 gtatttttta ttttaacata tatttaataa ggctaaatag agttattatt ttaatttcat
      121 actttacttt ttctataaac ctattataat taaagtataa tcatttttgc aacttgttta
      181 ttttattata aaaatgtgaa acttattaca taaggaggaa tttaacatga aaaatcatac
      241 ttataaagaa atcaaaaaca tatatggaaa aataagccct tttgaattta aggacaaatt
      301 aatagatatt gcaaaataca ctgcaaaaga aaataacaga gaattacttg atgcaggtcg
      361 tggaaatcca aactggactt gttcaactgc tagagaagcc ttttttactt ttggtcattt
      421 cgctattact gaaactcgtt ctaattggga tttaggtcat ttggctggaa tgcctcaaaa
      481 aaagggtatt aaagaaagat tttttaaatt tataaatgaa aatatagata tgcctggagc
      541 atatttagct agagatatta taaactttgg tataaatgaa cttggatttg atggagatga
      601 atttgttcat gaactagctg atggaattat tggtgataac tatccacttc cagatagaat
      661 gttacctcat atggaaaaaa tagtacacga ttacctagtt caagaaatga aatatgatat
      721 atcaggtaaa tatggtgatg tagaaatttt tgctgttgaa ggtgctacag ctgctatgtg
      781 ctatatattt gattcattaa tggcaaatga acttctaaaa aaaggagata ccatagcctt
      841 aatgactcca atatttacac cttatcttga aatacctaac cttcctcgtt acgactttaa
      901 agtggtaaat ataaatgcta atgaagttga tgaaaaaggt gctcatacat ggcaatatac
      961 aaaaaaagaa ttagagaaac ttcgtgacaa atctattaaa gctttattcg ttgttaatcc
     1021 taataatcct gcttctatag ctatggatga aacatcttgt aataatctaa tagatgtaat
     1081 tgaaaattat aataaagatt taatgataat atcagatgat gtatatggaa cttttgtaga
     1141 agatttttca tccttaatgt caaaactacc ttacaacact gttggagtat attcttattc
     1201 aaaatatttt ggagttacag gatggagact tggtacattt gcccttcata agaaaaatgt
     1261 ttttgataag aaaataaatg atttaactgg agaattaaaa aaatcagtag ataagcgtta
     1321 cagtgatatg agtcttaacc cttctagtct ttcctttatg gaaagagttg ttgctgatag
     1381 cagacttgtt gctctcaacc atactgctgg tctttctact ccacagcaag tacaaatggc
     1441 gtttttctct gcttttgcat tgattgacaa agtagatgcc tacaaaaaac ttaatatgag
     1501 tatctgccat agacgtcaaa aactattatt tgaagcttta gagcttccaa ttaatgaaaa
     1561 caaaaacaat gctgcatatt acactcaatt tgatattgaa gaatgggcta aattaaacta
     1621 cggagaagac ttatttaaat ttataagtaa aactgcatct ccagtagatg ttctttataa
     1681 attagctaat gactattcag tagttttact tagtggaaat ggattctatg gccctgaatg
     1741 gtcaattaga atatctctag caaatctata tgatgaagct tatactaaga taggaaaagc
     1801 cataagagag atattaaatg gttatatcgt tgaatggcaa aaaattaaga aataattata
     1861 ttacactgaa atatctaaat tatatgaata aaagagttta tgtagacctt aactactttt
     1921 tttgatataa tcctatcgga attataaatt ttatttatga aaggcagaga atagtatgag
     1981 tattaagaaa aaagttgcca tagtttttac tggtggaact atatctatga cagtagatga
     2041 taaagtcgga gcagctatac caactttatc aggtgaacaa atactatcaa tggttaccaa
     2101 cattgataaa gttgcagatg ttgaagtttt taattttgat gaaattccag gacctcacat
     2161 aacaccttat agaatgatgg aattgaaaaa ttatgtaaat gatttattag caagaaaaga
     2221 tattacaggt gttgtaataa cacatggtac agatagttta gaggaaacag cttattttct
     2281 agaccttaca attgacaaca tcaaacctgt aatagtcaca ggtgctatga gaagtagttc
     2341 tgaacttgga tatgatggtt caagtaattt atctgcatca gtttgtactg cagtatccaa
     2401 agatgctatg ggaaaaggag tccttgtagt tttaaacaat gaagtattat tagcttctga
     2461 agctactaaa acaaatactc tttctctaaa tacatttaaa tctctaacta gtggcccatt
     2521 aggaataatt gactgcaacg aacttgtcct tacaagagat attgtaaata gaacaattat
     2581 agatactgat aaggtagaat ctaaagttgc cttatttaaa gcatatgtag gagaaaatgc
     2641 tgactttata agatttgctg ttgatagtgg ttataaaggt atagttattg aggcaatggg
     2701 cagaggtaat attcctcctc aaatgctttc tggagttgaa tatgctagag aaaaaggact
     2761 tcctgtagtt atagtttcta gatgtcattc aggtagagta ttcgatagtt atggttactt
     2821 tggttctggt agagatttaa aaaatcttgg ttgtatattt ggtggggact taccaggtca
     2881 aaaagctaga ataaaactta tcttagcact tggaaaaact gataaccttg atgaaatcaa
     2941 agacttcttt gaaaaaggaa tctattgtta attctaataa cttctattta attatttatt
     3001 gatatttcaa catttttaaa tcaaaatcta atacttatgt cagttaaatg tcagcaaaat
     3061 attttatcca caatttttac acaaattttc cacaacttat ccccaatatt atccacaaga
     3121 aaaaaggtag cacttatatt agtagctacc ttttatttat taatcttcat ctttccagct
     3181 ttttatccaa tttcctattt ctattatttt ttcttcagtt atttcttctc catcatgtaa
     3241 ttttgaaatt agttctgata atggattgtt atgtagacct ccaaaaattc tttttccctc
     3301 tattttgaga tattctttct cttttattaa tactctatag tgtacatgtt tcccaattct
     3361 ctgcgatatg aaaaaacctt ttttagttaa tctagctaaa agtgtaattg tagttgtatg
     3421 cttccaagca tatgtttttt ctatttaatc tgcaacatct tttgatatta cagttttata
     3481 accagtattc catatgtatt tcataatttt taattctgca tctggtaatt ttttattcaa
     3541 cataatatat tccttctttc aatttatgtc acttcctcaa acttatctag cttaaattaa
     3601 taataggagc tttttatcac aaaaactaca ggtaaatttt tctatatatt ctacgtattt
     3661 agtctgtttt taagtgtgaa attacgttca tacctataaa tttattcaat tttcaaacaa
     3721 tcttgttgaa taataactaa ttctattgta ttatttagtt atagaataaa actaaatcgg
     3781 caaaactaga gaaatctagt gacgcaaagc tatagggact aagacttata taaatatctt
     3841 atgagttatg ttagccagtt gccaaagaga tattgttctt tttgttttta tgaaagtttt
     3901 ttagggggat aataatttat atgtttagag ataaaatgga taaatgtaca catatattga
     3961 ctgcttatat tagcaattcg tatgattatt gtaatttttt ggatacaatt tacattccat
     4021 atagttaata taaaactcaa ttaaattatg accttggttt agatagttca ttatttacat
     4081 tccatatagt taatataaaa ccagaaggaa tatctggagt tattggaggg tctattggat
     4141 ttacattcca tatagttaat ataaaacatt tactaagtgt agatataatt ataaatacga
     4201 tttaatttac attccatata gttaatataa aacctgtaga cttcaaccct acaatgcttg
     4261 ttggaagtgt atttacattc catatagtta atataaaact tttgtaaaag tttagaagtt
     4321 tatatataaa aaaaatattt acattccata tagttaatat aaaaccccaa aataaattga
     4381 gtatttccaa tgcctacaca tatacaaatc tctcaaattt gcagtgaacc atgagtagtg
     4441 caattgataa cacttatcac aagtcctcaa tgccttatat ttcaactgtt aagccttaat
     4501 ttcttcaaaa aatcgaacac tgcaaaattt ctatgacttt attatatcat aaaaatatta
     4561 tttttgaata tctgtaccaa tttgtgatat aataaaagca agaagaacta caatctattt
     4621 tgctgtagag tggagttcat aatttagaaa ttacttagtt ttatggaatc tgatttttaa
     4681 atcaaattcc caaccactct tagttgccgc tttgagtggt tttttacgct ttctaaatag
     4741 tttgctagct atataaacta ttaagctagc agatagactt gctagtatgc cttgtaaaaa
     4801 attatccatg tatattcacc tcccttctta gcgtcgggag gataattttt tgatacatga
     4861 actccactct ataaattgta gattacatct tcttgctaaa aatattataa catataattc
     4921 ttacatattt tacctattta ttacttttta cattataata atattctttt aatcaaaaaa
     4981 acacctacta ttaaagtaaa tgtttttaag tatttttaat tttaaaatcc atatagttca
     5041 tatgaaacta aatataataa ctcaacatat gagcaatatc gagacattta cataccacat
     5101 agttaatata aaacgaaaat aaaaaaatta aacttataaa acccttatta atttacatac
     5161 ccactagtta tttatattca aaaaaatctt ctccatctgg gttataaaat aatattctac
     5221 ttgccaatcc ttgttcatat ttataatttt ctttatcacc tacataagaa aatgttaatg
     5281 tcatgcttct tgatggatct aatgaaatta tatctaaata aatagtacat ttttctcctg
     5341 gctttaatac accgaaacta ttaaaatcca tttttatttt agcatattgc cccatatata
     5401 atgttgaatt agcttctcca taaactttta attttgttac atctaaattt tgtgtacttg
     5461 tattttctat atttatagga actgttgggt ctttatattt ttcagtataa tattcaaggt
     5521 tatcatcata acattcaaga taacttcctt tatcttgcca aattatgtgc tttgaatcaa
     5581 aatcaatctt taatccacat attatatttt tatttgaaga cggaagacta atattattga
     5641 tggtattttc acactctagc ataattttat cacttagatt tcctatccca gtcacttttg
     5701 cagcattttt aagtatatct ttattacttc caatatcaac tagtacaata ggattatttt
     5761 tagccattgg tgaagcaact aaagcataaa ctaaatcagt accactagct atataaaatt
     5821 cttttgcgcc attatagaac ttatttacta tttttttatt agtatcatat ctatctactc
     5881 cacctaatct agttgaatta gtatcattaa ctagtttgtc actcattgat gaagtaccac
     5941 ctattacata actttctaca ccagttgtat taaatggaac actttttcca tcagttaata
     6001 ctatagctgc tttatctcta actgctacag gtgcagcact cattgcatca ggctctcctt
     6061 taaaagcatt agtcaatata actttattta ctttgttaat tgagtttatt tcttttgcaa
     6121 cattatagct tgtcttaatt ctatcactac cttgaagtct tttagcctct attcctttat
     6181 cttttagaag agtttctgtt gctttatcaa tagaactttc tccacctatt atgtatacct
     6241 ttttagcttt ctctactctt ttaagagttg cattaggtat gttatttttc ttagttaaaa
     6301 aaattggtgc atttgttgct cctgcaagtc cactcgcact taatccatca gccattgtgc
     6361 tgtctgcatt aattaatata gctgtagtat aattttgttc atcagctata agagcagccg
     6421 tttcatattt atcttttcct tgaatagtat aaattgtatc aagtgcatta gctgatatag
     6481 gaccagcagc aaacattgac acggctaacc ctagtgataa taatttcttt aatttcacaa
     6541 tatctccccc ttttatatat gaaatactat atatcttaca taattctaca ttaaattttc
     6601 ttttcctcct ttaacgatat ttatcttcct gttaatttaa gtgtatacaa atacgtgtta
     6661 taatgtaact gtaaagaatt aaaaagataa tgacataatt agagcagtcc aactgttctt
     6721 ttataaaact aacttataaa gggagcgtac atatatgaat atcaaatcag cttttataag
     6781 aaaaagatgg gaaaaattct atgtatatgt ggaataagaa actggcaaaa agaaacaaaa
     6841 aagttatgga agctataaaa agaaaaagga tgctgaaaaa catttaattg aaataaagtc
     6901 tactataaat aataataagt ttgttgctcc aaaaggtatg acatttgtag aaagatgtta
     6961 taaatatata gacatgaata aaaataattg gtctccatat actgttacaa atacaaaatc
     7021 ttgggttaaa aattacatag aacctttttt aagaatctaa aactcacaga agtaaatcct
     7081 agttcagtac aagcttttgt aaattataac tttaataatt ctacctttac tagtgctaaa
     7141 gtaaggtata gctttctaag ttctgtaata agggaagcgt atagattaag agaaatacaa
     7201 gaaaattcat gtgattttat aaaacttcct tctaaagaaa aatattctac aaatgaaata
     7261 tacaatagag aagaagtatt attgctaata gaaaagttac ttggtaataa tatagaaata
     7321 cctattcttt taatgttact tctaggttta agaatgtgag aagctattgg gcttaggtgg
     7381 tcagatgttg acttagataa caatctgata aatgttaatc aaattcttgt ctattctaat
     7441 ggcaaaatat cttttaaaga gccaaaaaca ccaaaatcaa aaagagcttt atcagctcca
     7501 aaagaattaa ttgaaaaatt gaaaattgaa aaactaagac aaagcaaatt aaaattgtaa
     7561 ggtatcctgg aaaacagaaa taacttagtt tgtctaaaca ccaatttaaa tccgtttcta
     7621 ccttcttcac taagaaaaac gtttcacaat tttacaaaaa aaataattta aaaaagatta
     7681 gaatacatga tttaagatat acaagtgcca ctctgctgct tttaggggga actaatatga
     7741 aagttgtttc tgaaagattg ggtcatacag atataaaaat aactatgaat agatattctc
     7801 atgtacttaa agaaatggac aaagaagctt ccgacaatct aagcgaactt ctatttaaat
     7861 agtaaaaact gactgtcagt taaatgtcag ttaaacctaa aaaaataggt tttgtcagtt
     7921 gattatcagt caattatttt ataatagttt cacttaaaaa cgtctatatc tacacatttt
     7981 actatttgtt tatgcttatt aatatctatc tgttattatt aattctaata gcttctattt
     8041 aattatttag ttcagtttac aggaaactac acacaaacca taaaatagga tgttgacaat
     8101 ataacagata gtatgctcct gtaaaaggta acatagtatc tgttatattg tctggattcc
     8161 caaattagct atttggaact taactaaaaa atcctaatat aagggcaact attataatgg
     8221 caatcggaat acatactgtg taatcctgtt ccatagagtc atcatctgaa tgtagtttta
     8281 caattcgcaa tttagcaatc agtttgaagc agaaatagcc tattattgtt ccaattacgt
     8341 tcgtgagtaa gtcgtctata tcggttgctc tgtgtaacgt aaaaagctga atagtttcga
     8401 taaaaagaga taatccaaaa ccaatcaaga atgtatttct caaacgttca aaggttttgc
     8461 ttataagcgg acataaaaaa cctaatggga caaaaagtaa aatattcaaa ataaaactca
     8521 aactaaatcc atcactaaaa ggaataagat ttatgtttgg attaaagaac gtttccccta
     8581 actgtgacag tcttatatat tcaccgaatg taggtatacc aacaatatgc gatagtgtta
     8641 aacataagta gtaatacatt gccagtgata aaatagatgt tttgaccttt ggaatatcac
     8701 tatttttctt gaatattaca actaagaaaa taccaatcaa gataattccc aacaagaaaa
     8761 taggattaat taacaataaa tctttgatag cttcaaacag actgagttga atttctacac
     8821 ctgattgatt atttgttaca gtctccattt gtacatacct cctcataaca tttcaattat
     8881 ttctaaaaaa caaaatagaa gataaatctt aaaatcatcc tatcaaaatt tttaaatttg
     8941 cctttatcag tttataccac cagttaattc ctgtcttact tctgtatggt attcttggga
     9001 ttctttcatc aaattagaca aaaaatggtt accatatcaa taaactggtt acgctccata
     9061 tctcccgaag caaccatccc ctgagaataa atccgtatca ggaatctcca catctactgc
     9121 acctatcaca agttatttga taacatcctc agacaatccc aacttggata tatcgacaac
     9181 acccattaga ataccactgc tgaccatact tgttttcctg ctgataattt taatcaactg
     9241 ggaagttgaa acgctatctt ttttacaagt tcctttttag aaacatggta gctattatat
     9301 gaatctgaat ttcgttgtct gggtgtttca tataaagcat agatatgcac cttttttgcc
     9361 tgttttcatt atatagaaaa aaatttcaaa atacaataat tatatttttt tcgtttaagc
     9421 ttagagcagt tccttgacga acaacacttt ggaaactgaa tgatttacat accacttaat
     9481 acattaactc gatttaacat taattataat aatatttaaa acaacaacta gggtatataa
     9541 gaatgaactt tttagttctt taatcatttt tttgtataaa atcaaatcta tttttataat
     9601 ttcaacaatg aaaaaaggct tatctctatt ttgagacagc ctcatttatt ttataaattt
     9661 atatttttgt tcatattttt gagttattta acaactatat ttactaattt tttaggtaca
     9721 gctacaactt taactatagt tttaccttca actaatcctt ttattttttc atcttctaaa
     9781 gctacctttt ccatctcatc tttagatata tttgagttaa cagttaattt tcctctaact
     9841 tttccattaa cttgtacaac aacttctatt tcatctttta ctaaagcttt ttcgtcatat
     9901 ttaggccagt ctatatcaaa tacacttcct tctttaccta tcatagtcca tagttcttca
     9961 cctaaatgag gggcaaatgg tgcaattata gttactatag tttgtacacc ttcttttata
    10021 actgcttcgt ttatattatc taactcttta tatttataca tatcatttat taattccata
    10081 agagctgata tagcagtatt aaatccgaat ttttcactta aatcagcagt aactttttta
    10141 agtgtagagt gtatagtata tctcatatcc ttatcttggg aatttaattc tccaaactct
    10201 acatcctttt taaccacatc tgctaactcg tcaaccaatc tataaaccct atttaagaat
    10261 ctaaagcatc catcaacacc ttgctctgac cagtccaaat ctctttctgg tggtgctgca
    10321 aataatacga aaagtcttgc agtatctgct ccatactcat ctattatatc cataggagat
    10381 actgtattcc ctttagactt actcatttta gaaccatcca taagtaccat tccttgagta
    10441 agtaagtttt taaatggctc attgaagtct accattccca tactcttaaa tgcctttaca
    10501 aaccatcttg cataaagtaa atgcattata gcatgttcta ctccacctat atattggtct
    10561 actggatgcc atctattaac taattcctta ctaaatggtt cattttcatt attgctatcc
    10621 acatatctta agaaatacca agaagaatca acaaatgtat ccatagtatc aacttccctt
    10681 ctagctggtt ttccacagtg aggacaagtt gttgacataa attgctttga agtcgtaagt
    10741 ggagattccc cttttccagt aaattcaaca tctgttggta aaagaactgg taaatcttcc
    10801 tttttaactg gaactattcc acattcatca caataaacca caggtatagg acaaccccag
    10861 tatctttgtc ttgaaactaa ccagtctcta agtctataat taattgttct ctttcctcta
    10921 ccttcttttt ctaacttatc gattattcct tcaaatcctt ctgaagcatc taatccatta
    10981 aattcttctg aatttatcat tttgttatct tctgttatta catcaattat gtctaaatta
    11041 tatttttcag caaaatctct atctctttca tcatgtgctg gaactgccat tatagcaccc
    11101 gttccatact caactaatac atagttagct atccatagag gaactttctt gccatttaaa
    11161 gggtttataa catatctacc tataaacatt ccttcttttt ctacatcagc tgctgttctt
    11221 tctatttctg tcatagtatg cattttttga acaaaagctt caacatctgc ttcatattca
    11281 gtccctgcaa ccaattcttt aactaattca tgctctggag caagtaccat ataagtaact
    11341 ccataagttg tgtctggtct agttgtaaat actgtcatag atttatcagt tccatctata
    11401 tcaaaaacta aatctgctcc tgtactttta cctatccaat ttttttgcat tgttttaact
    11461 ttttctggcc atccatctaa tgtatctaag tcattaagta attcttctgc aaactcagta
    11521 gtcttaaaat accattgttc taaatctttc tttaatactg ttgctttaca tctctcacat
    11581 gctccttgaa caacttgctc atttgcaaga acagtctcac aagaaggaca ccagttaaca
    11641 tatgattttt tcttatatgc aagcccatgc tctaaaaact tcaaaaatat ttcttgtgta
    11701 aatctatagt attctggagt tgaagttgca acttctttat cccaatcata actaatccct
    11761 aataaattta attgctcttt catttcttct atattttcca ttgtccattt atgcggatgt
    11821 attccatgtt ttatagctgc attttcagct ggtaatccaa aagaatccca tcccattgga
    11881 tgaagtacat tatatccttc catttttttg aatcttgcga caacatcacc tatagaataa
    11941 tttctaacat gtcccatgtg tatttttcca gatggataag ggaacatttc taatgtgtaa
    12001 taattaggtt tttcagtttg tgcagtatcc attttatact gattattatc tttccagatt
    12061 ttttgccatt tcgattctac ttctttaaaa ttatatacgc tcatattttg cctcctattt
    12121 ttaattgtgt ataactacct tatttagtat tatttactta taatttccaa ataattcttt
    12181 gaaaataaaa aatcctcgtc actaaactta cgtttaggga cgaggataaa tcttcgcggt
    12241 accaccctaa ttagcctact acatatatag actctcttag atagctttta atccagccat
    12301 ggagaataga ttttaatcta gtaagttcaa agttatataa tattagttct caccttccac
    12361 taactctctg aaaaaatata atcttttact gctctagtct attcaattta atataatttt
    12421 tgaaattttc taattataat aacatatatt atcatgttta tgctaatgtg tcaatatcta
    12481 tataaggtgc atctttccat aatttttcta aattataaaa ccctctattt tcctcattaa
    12541 atacatgaac cattatgtct ccataatcaa ggagtaccca agtttgagtt ccttgtcctt
    12601 ctttacctct tggctctaat cctagttttg ctaattcatc ttccacattg tcagcaatag
    12661 cttttacctg tctctgagaa gatgctgtag taataataaa ataatcacac aaactagaaa
    12721 cttttcctat atttattata actgtatctt gacctagttt atcttctatg gcatcatatg
    12781 ctatttttgt catttgttcc actgtcatat aaaaattcct cactttccta attaaaatac
    12841 acttagttat tgtaacatat taatacgatt ttgtaacata gtcaaattta aatttattaa
    12901 tatgtttgcc tttatatagc ttttttataa taacttttct ttaattagat agtttcttgc
    12961 cataactgtt cttggatgta tctcttcttt tttattgatg acaaacatta aagtattatt
    13021 aaaagaagtt aaaagtgctt catcaagctt ccctccatat gctaattctc ttaatgtatc
    13081 tacaactggg aattttcttc cttcttcaat taaatcagct atgtaaatta ttttttctaa
    13141 aagagacatg tcctctctcc ctgttgtatg atatttgatt gcatttataa tatcttcatc
    13201 ttctacttca aattcatact cgcatatgta cgccccaatt acgctatgag acaaggaacg
    13261 atttccatcc tctattgggt ctaaatatat ttcatactta tttacataat cctctatttc
    13321 cttgtcactt aaatactttg cacaatcatg aatcattcct gctaagtaag ctttttcttt
    13381 gtcacatcca taaatctcac ataatttttc agcacatttt gcaacatttt ttgaatggct
    13441 aagcctcccc actggtagca tttgatttag tctttggtta atattttcta agttcattta
    13501 atcatctcca tattgatata gtttattttc atataaataa ttttctacat tttcgggtac
    13561 taagtaacgt attgacttgc cttcatttag ctgttccctt atatatgtgg acgatatatc
    13621 cagtgatgga acataaactg ttataatgtc agcattatac ttcttagtta gtttttctat
    13681 agtctcttgt gaccttaaca aactaattcc tggtctagtt gcggctataa aagtagctaa
    13741 ctcaaagttt ttctttacat ctttccactc ttcaacacta caaattgcat ctgcacctgt
    13801 tataaaataa atgtctgcat ttttgtattt tttctttaag tattttaatg tatctattgt
    13861 ataagtcctt ttctttcttt cgatttctac ttttgaaact aaaaaatctt cgttgctttc
    13921 agttgctaga agtgtcatat tatatctatc atacttatct gtagtgatac ataatttatg
    13981 tggtggattt cctgatggta taaagattat tttgtcaatg tcatacttgt ctctaataaa
    14041 ttctgctgtt gctaaatgag catagtgtat agggtcaaaa gtacctccca atatacctat
    14101 tttgattttg cctttatggc gattaaattt ctctagtttt tcagtatttt tcaactctgc
    14161 catcttaact agattttcac ttctcatatt ttgtctcctt ttaatgttat aatactattg
    14221 taccattatt ttttatttct taaagcttat aatttgtttt tttgggtata taattatatt
    14281 tatatgctaa aaaacactta aaaaaataat tatttaacat gattctactt tactttttaa
    14341 taaaaataac tttttactat tttgtcttaa ttttgataaa atataacata caaatataag
    14401 ttttttgtta aattttatta gttgcttttg ttaatataat tacatataaa aaaggaggac
    14461 ttatgggtat aattacaaaa atagaacaac aaaaaagaaa tgatgataga gttaatattt
    14521 atgtagatga taaatttttt attgctatat ttaaagaact tgtttataca tttaatttaa
    14581 aaaaggggaa tgaaataaat gaagaagaat taaaacctat tttagatgat gaaatgtata
    14641 taaaagctaa aaataaagca ttaaatattt tatctcatgc tgaccaatct gaaaaaaaat
    14701 taaaagaaaa actatcatca gaatttgatg aaaatataat tgagagggtc atagattttc
    14761 ttaaaagtta taatctcgta aatgacagtg tattagctca aaaaattgtt aacacaaatg
    14821 ttaacctaaa taaatgtggc aaaaacagaa ttaagcagaa tttatataat aaaggtatca
    14881 atagaagtac aatcaatgaa gcagtatctg aattagacaa ggacactgaa tttgaaaatg
    14941 ctatgtatct agcaaaaaaa aggtatgaaa gagtaaagaa agaagataaa aagaaaatat
    15001 atcaaaaaat ttctcaacat ctttcctata aaggctttga ttatgatatt attaaaagag
    15061 ttttaaacaa acttttaaat tttgatgaat acgatatata agtataaata ctagggaggt
    15121 aaattatgaa attaatcatt ggtggcttaa gctttttatt aggattatat aatatatatc
    15181 aattatatag agaagatagt atgagataaa tattattttt tagatgtaat atttattatg
    15241 gaggagaaat acaatgaaaa gtcaaaaaag atttaaaatt ttagatattg atgtatacct
    15301 acaaccattt gaatctgata taaaaaagcg aatgaaacat tatgagaata tgaaatcaaa
    15361 aacattgaaa aactataaag attttagttc ttttgcaaat gctcatcttt actatggatt
    15421 tcatcagaca aatgatggat tcttctatag ggaatgggct ccaaatgcag atagtttgtc
    15481 actaattggt gactttaata attggaatag aaaatctcat cctctaagaa aaattgggtc
    15541 tggtaattgg gaaatattta ttcctggtca aaatagctta cctcacaaat cagaggtaaa
    15601 ggtacaagtt actgcaaatg gaaaaacatt tgaccgtata ccattatata taaaaagagt
    15661 aattcaaaaa gattttggtg gatttaatgg acaaatatgg caaccaaaaa ctccatttat
    15721 ctggactgac aatgattttg acttaaaaaa cataacttat ccactaatct atgaatgtca
    15781 tataggtatg tctactgaaa gcgaatctat tggaacttat aatgaattta ctgaaaaaat
    15841 acttcctaag ataaaaaaag ctggatacaa taccattcag cttatggcta ttatggaaca
    15901 tccatattat gcatcttttg gataccaagt ttcaaacttt tatgcaatct catctaggtt
    15961 tggtactcct gaagacttaa aaaacctcat aaacactgct cattcaatgg ggattgctgt
    16021 tttattggat ttagttcatt ctcatgctgt aaagaatact ttagaaggaa taaatgagtt
    16081 tgatggaagt gaacatcaat ttttccactc aggttcaaag ggaaatcatc ctgcttgggg
    16141 tacaaaactt tttaactatg gtaaacctga agtaatacat tttttgcttt caaatataaa
    16201 attttggtta aatgagtacc attttgatgg ctttaggttt gatggtgtga cttcaatgtt
    16261 atatcataac catggtcttg gagtttcatt tgatagttat gaaaaatatt ttagtatgaa
    16321 tacagatatt gaagctataa catatctcca atttgcaaat gaattaataa aagaaattaa
    16381 acctaattcg ataagtattg cagaagatat gagtggaatg cctggtatgt gtatccctat
    16441 aaaagacggc ggaattggat ttgactatag actcgcaatg ggagtacctg atttttggat
    16501 aaaaactatc tctaacttat ctgatgaaga ctgggatttg ggaaaaatgt ggtatgaact
    16561 tactactaga cgacctggag aaaaaaatat aggatattgt gaatcccatg accaagcatt
    16621 agttggcgat aaaacaatta ttttttggct agctgacaag gaaatgtact ggaatatgga
    16681 aataaactca aataaccatg ttatcaatag agcaatatct cttattaaat taattaaatt
    16741 aataactttt tctctagcag gtgaaggata tctaaatttt atgggaaatg aatttggaca
    16801 tcctgagtgg attgattttc cacgagaagg caacaattgg agctataagt atgccagaag
    16861 acaatggagc ctttcagaag ataacaactt aaagtataaa caattattaa attttgataa
    16921 atctatgctc gaacttacaa aatacagtga tatttttatc caaaatagtc atgaacttat
    16981 acatatggat aatgataaaa agattttggt gtacagtaag ggcaaatatt tatttatatt
    17041 taatttccac cctaatctaa tacaatcagt tgatatttca aagtttcaaa atacaaacta
    17101 caaaacgata ttaaatactg atatggtaga gtttggagga aacacaaaaa aagaaaactt
    17161 aagagattat gatgtatact ttagctcaac tcctccttct tctaaaatgc ctattgcctc
    17221 tcgtacagca atagtgcttt tagatagtag tatttaaggt tggtttttct agtatataac
    17281 actcatatta aaataaacac taaaagccaa ataacaattt aaatacaaaa tgttatttgg
    17341 ctaatttagt ttgatactat ttaactatct tttacattaa gttctataat ttccaacttt
    17401 taatttgtgg tattatattc atcttaacag tttgattctt taaagctttt ctaaatttct
    17461 cagttgaaga atctttaaac attttactag aagcactctt gaggtcttct atagattccc
    17521 aatgttgtat cataatccac ttttgagact tttcatcata taaaagctca gtatcaataa
    17581 aaccagattg aatagaatga aattttaatt ctaagtcatt tacaatttct ataaactctt
    17641 cttttgataa attttcttcc acattaaact caactatttc tgtaataatt ttcatatgta
    17701 aaacctccaa tttattttcc tatatcatat caaaaaataa attggaggta ttgtaaaaaa
    17761 tcgacagtat aattataaat agctgtactt tatattttct ttaatcgtct tattctcacc
    17821 aataaattta attggtgacg tccctgaaaa ttttttaaat tcttttataa agtgtgcttg
    17881 gtcatagtac tcattttcat aaataaaatc aaaaagttca tcatctttat aattataaat
    17941 aagttgattg cttgccattt taaatctgta aattctcttt aaaatcttag gtgtataccc
    18001 tgtatatttt aaacagattc tttccaatgt tttaatattt atatttgtat catcacaaaa
    18061 tgcttttata ttgctatatc tattaacata tataaatgaa tttagaagct ttacatattt
    18121 atttgaaatt aaatcttctt ctaatatgga taataatact tcttctaaat ataaaacaat
    18181 tttttctact gattgtgttg gatttaatga ctcttccaat ttttttgcaa atagctgtga
    18241 tactgcttct aggtcaacaa tttgtctgtt aaactctgaa attggtatct ttaaaaatgg
    18301 atagagacca aatggataaa aagaaatccc tataacacgt atatttccat gttgaataat
    18361 aaatccatgt ttatccctta ttccattaaa atgcatatta ctagcagtat agtcttgatt
    18421 ttcaatttta tattccataa catcagaaag attgagaata atatctatac tgtctgtcgg
    18481 aagtaactta ttatttaaca gtatatttga ttttgtctca aaataccaaa taaactttac
    18541 ccacggcttt aaacgaacat ttttgattga atatcttgta actgataaca ttgtgaacta
    18601 acctctatac taaaattttt taattatgta ctccatccta atattataca gtataattta
    18661 tgctatcata aattttagtt cactttatat ttattttata cattttttca ataccttaga
    18721 aataggaagc gctattataa gacctatcaa tacttgcatt aaattacctg gtattgaagt
    18781 aagaggtact ataaaattac cataaagtat aacttctgtt acataatatc caaatagcat
    18841 ccaaattgat gaaacacata ttcctattac attgattaaa aaattattcc cattattacc
    18901 atttgcccat gcaatctttc caagtaaata acccataact cctctaacta taaaggtaaa
    18961 cggtgcccat aaagtccacc cagatatcaa atcaaaaagt gacataccaa tagcccctga
    19021 taaagcacct tttttacctc caaatactat tgctgatatg aacaacattg cagttcctaa
    19081 atgcacaagc ccaccattta tagatattgg taatcttatg tttataaatt tagttgcaat
    19141 aaatactaat gctattaata gtgaggtttc caccatgtct ttcgttgtaa atttttgctt
    19201 agctgtaact tccatactat atccccctat ctattaaaaa taatacttat taaataaatt
    19261 taacaaattt ccatttcctt tgaatcctaa tgcacttaaa cttttatcca aaacatttag
    19321 tacatgttct attttattta gatttgcatt ctctcccata tgacctattc ttaaaatagt
    19381 atccatatat tgatttagtg atgttgcaac aagtgtatta taatttttaa gcatataatc
    19441 agtaagttct aaagctccta tactttcagg aatttttata gctgtgactg tattagaata
    19501 tccttcttct aaaaatagtt ctagaccata ttcctcaata gattttctaa cactataagc
    19561 tatcttttca tgtctattta atacattttc tattccttct tctaatatat tatcaagtgc
    19621 tttatcaagc cccattatgt cacttattgg cattgtataa gggaagtatt ttttctcata
    19681 atagccttcc catatattta aattacaata aaaacctatt acatcagttt ttctattttt
    19741 tatacaattt tttgcatctt gacttattcc gactatagta agtcctgctg gtgcagaaat
    19801 agctttttgt gaaccaccta atattatatc tattttagat tcatctacac ttaatctttc
    19861 tcctaccata cctgctacag aatcaactac agttaatatt ccatattttt taagtaatgg
    19921 acatattttg cttacatcat ttaatacgcc agttggagta tcacaatgca ctactgttgc
    19981 atatttaaaa ttactatcct catctaaaaa tgctttcaat tcatcaatat ctatactttt
    20041 agtatactca cttgaaaaaa gcacatactc cccaccatac attgttacaa aatctttaaa
    20101 accttctcca tatataccat tgtcaattac aagtactcta tctccttttt ctgtaagtga
    20161 tgcacatgct gcttcaagac ctaatattcc ttcaccactc aatatgtaaa catcgttttt
    20221 tgttccaatt atattaccaa acttctcgca tgtcttttta taaaattcaa caaaatcaat
    20281 atctatatct ggatttgttg ttttttctgc tcttgctaat cttacatttt ccctagtttc
    20341 agttggtcct ggtgcataat taatcttctt attcatatat atcagctcct atttattttc
    20401 tatacgatta ttatacaaaa ttttcatttt atatggtaca attttatact tttttagaat
    20461 tgtaccggta cattttctaa catgaataat atcagtatat tagatatatt attgattaca
    20521 taataaaata cagagcaaac atctgtttaa attgtttgct ctgtactatg ctttaaccta
    20581 tttaattatg aatctcttta actatatttt tttatatgtt ttttgctagt taaactaacc
    20641 ataaatattt gcattttatt cactgtatct tactctatca ataagagatt ctttattaaa
    20701 acttcgtcct atcaaataag ttgttataaa ttgagctata agaatacaca caatcatcaa
    20761 caagattggt actattggca aagaatatgt tgcataagat aatccagtct tttttagaaa
    20821 tataacagca atatacccta atatacctcc aaatagaata cttcctatca tcattccaga
    20881 agtgtaatat attgcctctg aattaagcat tttcactaat tgtttattag taagaccaat
    20941 agcttgaagc ataccaagtt ctttttttct agtaactatg ctagttatca ttgtgttgac
    21001 aagattcata aatccaatca cacctattat gcctgttagc gtgtatccca ttatctttat
    21061 aaatgaaata gtagccttat ttgactcaat tctactatct ataaaatcag tctctaaaaa
    21121 tccattattt ttagcaatct tcttgatact atctttgatt tcttgatact ttccttcttc
    21181 tgtatatatt cccaagctac tagttgaatc gtatttcaaa gttctatcta taaaatcttt
    21241 ccctatacca aaacttggaa cccccatagc tattgcttga actttaaatt ctttttttat
    21301 ctttttatct ccatcatata aagttaatct tattttatct cctgctttta ctcccatttc
    21361 ttttgctgta tcaacatgag taattactat ttcatctcca gtttgaagtc tttcaagatt
    21421 tatttttcca tctattatat tcttgtttaa tgattttaca tcattttcat ttatactttg
    21481 taaaaggtca tacttaaatt caacatcata gtcctccata ccaattttta cacttcttgc
    21541 agattctatt cttttaattc cttccatgtt ctttatttga ttaaaaaaat ctttacttag
    21601 aggattatcc atttgtaaaa tattcaaatt atctttagga tttttatcac tgttcatttc
    21661 ataaccagat agtctaactt ctatatcata aggaaagtgt tctcttgcca ttttctcagc
    21721 atcaaaactt tctaaggcag ttgatactgt tataaatata gttccactaa gtataagtga
    21781 tgccaatgtc atgtaagtac gttttttatt tctttctaaa ttggcatgtg ataatctctt
    21841 tagatttata tttttatatc cttttctctt actcttatta cttattttat ttcctgtata
    21901 tcttactgcg tcaacaatgg atacttttga tgctactttc attggtttta aaagtgataa
    21961 aacaacagat ataaagctta ttaccacaac cgataatata actggtaatc gtgatgattt
    22021 tacatctata tccataaatg attttattat aatatttgca agtacatagc ctaaaattat
    22081 tcctattggt atagctattc cggctaatat gaacccttct ttaaacacta tattttttat
    22141 ttgtttctta gttgcaccaa ttgctctaag ttttccaaat tcttgaacct ttgtaactat
    22201 tgaaatataa aatatattgt atattactaa aatactagat aatacaatta ctaaccctac
    22261 aaaaactcca cccataatcg tttccatatc tggttttaaa gcatttatat aattttcatt
    22321 tacagcagta ttaatagtat ccagtcctat atcattagca attttatcta atttttcttt
    22381 tgcttgctct attgataaat tacttttatc attaaatttc acataaatat taaaatcttc
    22441 ttgtgacata tctctagtat ttctcatata tgattctgat ataatagcat aataatattt
    22501 acctgcttca gatatttcgc tagtttttaa gattccactt ataatgaact ctttttcaat
    22561 ttttttatca tttttatagt catcataaga tatttttatc ttttcaccta aatctttatt
    22621 tttataacca agtgccttta aagctccact atctaacaca atttcattct cttttgatgg
    22681 caattttcct ttgataaatt caaaactatt taatttcaaa gcatcttcat tcatgtatgc
    22741 tagagaaata tttgaatcat cttccagttt ttcaacacct actccattca tttcaccagt
    22801 taattcaaca tctgcatgat tactcaatat atcagcctgt ttttcatcta catttgctaa
    22861 tataccttga taattgcctg aatactttat agtattttct ttttgatatg ctcctgcatc
    22921 aacaatataa attccaatag aagaaagcat taaggttgaa agtattatag taattattat
    22981 tagaatactt tttgatttat tttgctttaa attacttttt gctattttag tagtattaat
    23041 catttttatc accaaccttt gacaccctgc catcttctat gaatataact ctatcagcca
    23101 tttgggctat actgtcatca tgagttatca taactagagt ttgactgtac ttcttagaca
    23161 tagattttaa tatactcata acctcatcag acgttttaga atctaggttt ccagttggtt
    23221 catcagcaag tattatagct ggtcttgtag ctaatgctct tgctattgcc accctttgtt
    23281 gttgaccacc tgataatgta tttggtaaaa cgtcgtgttt attttcaagt cctaatgatt
    23341 ttaaaagttc ttttataaaa gattcatcta cttctctacc atctaaaccg attggcaaca
    23401 ctacattttc ccatacatta agagatggaa ttaaattata gctttgaaat ataaacccta
    23461 tttttcttct tctaaataca gcaagttctt cttcttttaa tgtaaatata tttttattat
    23521 ctatatacac cttcccagat gtaggtatat caagacctcc aatcatatgc aaaagtgtac
    23581 tttttccaga acctgatttt cctattattg caacaaattc accttcattt atttctaagt
    23641 caacattgtc caaagctctt actaagcttt ctccttttcc ataatgcttt gataaatttt
    23701 cagtatatag tattttcata aaattatcct ctcattctaa gttatattac tccatatttt
    23761 attaattttt tatttctgga gctgtttata cttatataat aaatgtagag gcttacattt
    23821 tcctttcatt taatattaca tagttgtaag aaacaaagaa aacttgctcc ctattcctac
    23881 ttttgaagaa actataatat ttccaccttg ttcttctaaa atctttctac ttaaatacaa
    23941 tcctacccca ctaccttcta cagattcaat ttcatcagca gaacctctat aaaaacgttt
    24001 aaatatatta ttaaactcat ttttttcaat ccctatgcca ttatcctcta ttataatttt
    24061 aaagaaatta gcagtttctt ctacagatat atttatttct ccatttacct gtgtatactt
    24121 tacagcattg tctaatacat taaaaatact ctcctcagtc cactttttat catgtggtat
    24181 aattctactg ttaaattcat ttaaatttaa tgttatactt ttgctcttag ccttaggggt
    24241 aacacttttt actgcattta gaatagtatt ttttatatca ttatcttctt tttttatgtt
    24301 tatcatgcta atttctaacc ttgatatgtt cactaaagaa tttattaaat tttctaattt
    24361 atttatagaa gccttattgg ttaataagaa ctcgttggct tcatcttctt ctaattcttc
    24421 ttctataagt aatgtattgt ataattttaa ggatgctaaa ggagttttta attgatggga
    24481 aatatctgtt actaatgatt ttacactttc tttttctttt tctaatttaa taaactttat
    24541 ctttaaactt ctattaagct catatagaca gttatttatc ttactaaata tgccttcttt
    24601 aaagtattca ttatattcta ctagataacc agtttcttct tactcagtag tgtccttcaa
    24661 gtagttttct tgtgacatct tatctactat aaaataaatt ttactcaatc ttttatttat
    24721 gtatcttata aaataatata ttatacctat aactactata aacatcatta aaaaaataaa
    24781 aaatgattcc ttaaaaaaag attttaagta taagctaaaa tttttatcat ttgacatttt
    24841 attttccaat ccatagccaa atttcttaaa tgccttttct ccagtagaca ccttactata
    24901 atcagaatta taaatagaat ttactatatc tatttcatca ttaggatatt tttcaatcaa
    24961 tattccagca atattttgag tgttttttat ttgatgttca tacaatttat gtaatctgct
    25021 atattcaaaa agtataaata caagggttac tattagtaca gataaaacag aatatacaat
    25081 aactcttctc attatataat catctttcac acttaaacca tctttgaggt tcatattttt
    25141 tagcattttt ttatactcct ttctccccac atatatccaa cccctcttac tgtttttata
    25201 tatttaggtt cagatggatt tttttcaacc ttttgtctaa gtcttcttat atttactgca
    25261 atcgtattat catctacaaa attaccacta ctatcccata aagattctaa cagttgctct
    25321 ttagtcaatg tctgcataga attttccatc aaatatttta atagttttgt ctctgtctta
    25381 cttaaaatta tctcttcttc cttatcatct gttcttataa ttaatttatt ttctatataa
    25441 taaaagaata aatcatcaca aactaataga gtataatttt ttactgtatt tactcttttc
    25501 ataagcgcat tcacttttga tattaatacc atcaagctaa aaggctttgt gatataatca
    25561 tctgcaccta aatcatatcc tgtgacaata tccacctctt catcaagagc tgtcaacatt
    25621 attatgtaaa catcactttt ctttctaatc tcctcacaaa agtcaaaacc actaccatca
    25681 ggtagaccta tatcggaaat aattaagcat atctcttctt ttgcgaaaat attttttgct
    25741 tcttctatac caaatgcact aaaaacattg tatccttctt tttttaattt aaaactaatt
    25801 cctctattta aagatttgtc atcttccaaa agtaatatat tattcatccc tatatcctcc
    25861 atcatcatat atactagcta aattatatca tactaataaa atcatttttt tatcaatttg
    25921 taaatatatc agaagttgtt aatatgattt catttacttg aataaaaact aaaaatcccc
    25981 ataatactat gccatttagt gtaattattt ttcataaaat acaattttat ttaaaagtaa
    26041 tcatgttaaa acataaaaca aaggaaatta gtatttatat aactaatttc ctttgctgtt
    26101 tactattatc taaaattaaa ttactatcta ctaatttttg ctcattaatt tttattttga
    26161 ctttttatcc tttaactctt tttgattaaa attcaataaa catatcaatg tacttgaaac
    26221 tataaatata attatactat ttgaaaaacc taaatctcct gttttaggag atttttcttt
    26281 agcttctctt ttagatattc ctagattaga actttctcta gcacttgttt tatctaagct
    26341 tttattttta tcactatcag agctttttat attattagat agattctctt cattatcatt
    26401 gatatttttt tcattttcac ttaatatcaa atcactctca tgattcttgc ttattaactc
    26461 atctttagat ttaataccaa ttcttccatc tacatttttt gatatttctt ttttgtactc
    26521 tatatattca atgactgcac tctctaaatt tccaaattcc tttagtactg gctcttttga
    26581 aaaacaagga aattcatctc cacctgatgc tatataatca ttcgttgcaa ctacatactt
    26641 tttatttaaa tctaatggct ttccttcttt ttgaatattt gttatttttt cgccttcttt
    26701 ttgtttagga ttaaagtaat atgaaattcc tcccacttgc aaaaaggctg aacttttttc
    26761 tggataaagt tttactccat gctccaatac atctttaatc tgtgctcctg taagttcttt
    26821 ggtaactata gtattgctaa aaggaaatac atctacaata tctcttcttg ttatattgcc
    26881 tttttctatc gtatctcgaa tattccctcc attaaataaa gaaatatcag ccttagtttt
    26941 atctagtaaa atgtcactta ttaaattacc caaattagtt tcttttgtcc ttacattttc
    27001 atatgaacca tctagagtat ttgtagttac ccctataact ttatctaata ttttttcttg
    27061 ttgttctttt atttcatcaa cctttttact tacagcggag tcaagcttat actttaatgc
    27121 ttcttctttt ccaattaatc taactgattt attttctatt tttatatttt ctacatcatt
    27181 agtatccaaa gttagtttta tctcgccaat attttctaaa tattgtcctg cacttacaat
    27241 caatgtatca cccacttgtt taccattttc aaacttagtg tggctgtgtc catcaataat
    27301 caaatcaatt ccttgaacct catttgctat atctatacta tttggcttac ttaaactatt
    27361 tgtaccaata tgacatattg caactattac attggcaccc tttcctttta attcatttac
    27421 ttgttctgtt gcactttcta taggattttt aaactctaat ccttccacat ttttaaatcc
    27481 agttttgctc tttgtttcct gggttgagag tccaaaaaat cctattttta ttccatctat
    27541 ttcttttata tcattactat caaaaacttt ttttccattt tcaaaaatat ttgatgataa
    27601 aaattttaaa gtattctctc ctaaattagc acttttagat aactcaaaca gtctatcttt
    27661 tccataatta aagtcatgat ttccaggagt aatatagtca tatccagcac atttaattaa
    27721 ttcaattgca cttttccctc tatccatatt tactattgga agtccatgca aacaatctcc
    27781 tgcatctact aaaattgagt ttggagtttc ttttttcaat gtggctagat ttcctatttg
    27841 tatatggtca tcaccttcag catatcttcc atgtatatca ttagtgtgaa aaatggttat
    27901 ttcttcaaat cgctctagcc cataagaaat aaaactctga cttgttgtaa ttagaattat
    27961 aattaccaaa attaaatacc ttctaatctt caatataaat tagcctcctc aaattagttt
    28021 tagctttaat ataaaattta tattttacat aaaacttttt agataaatat taaactatag
    28081 taagattaat tagtgtaatt tttaatattt atctatcaat ttaattttgt ccatatccaa
    28141 ttagttttaa tctaattaca ttttttcaca tctatatttt tcttttatta tataaaatta
    28201 ttattttaaa atcttttcaa ctggtctctt ttaaaagtcc attgaggtat tgtcaaatca
    28261 ccttcaaaat ctaaactata ccaaggactc aaatttggat ttttacgatt aataagaagt
    28321 tgcgtttgtt gtgcaggcat atagctttgg gctatcataa ataccttttc accagtcttt
    28381 tcattttctg ccatatccat aattatactt gcatgtcctg gacttccacc aactataaac
    28441 acatctccta ttttcatatc ctcaactttt acaggctcca attctttttc aagagataac
    28501 gttcctgaat atgcaaacac tatatccata aactttctaa aactctcata agatgttgaa
    28561 tattcagttg ctttatacca gcttgaacca ctatctttta ctgaaattct atatccttgt
    28621 gcccattttg aatacttcgc cttaaaacca tcaacaaaat caaaacttat ttcatcatat
    28681 agtttattct gatacaagta ttctgctctc ataagcataa ttgcatctgc acattgatgc
    28741 aaatctctat tgccaatatc aacatcaaat acactatcat aaataccttt tgattcctta
    28801 gttcttccat cataatactt tactttctct ccataatttt ttagcttagt attcctaaga
    28861 aatgattcaa aactaccttt ttctacatca actcttttaa atccttttgg tggctcatac
    28921 ctatctttca atatatttgc atctttatgt actattatag gctgttcatc ttttttagaa
    28981 ttttgaattt tcttagaacc ttcaaccact tttttatctt ctccgttact acaaccaact
    29041 aaggttaatg taattaatga caaaatagta attttcttta atactttcat taaattttcc
    29101 tcctttaaat gctcctaaat ataattttca ctttttgttt tccaaatttt tatacatttc
    29161 tatataaaaa ctttatttga caatatttct tgactcaaat acacatttat tgttatattt
    29221 aatgttaaaa taattataat aggatatcat aataaaaaca aacaacagat ttgtgttaat
    29281 tttagaaagg ggaaaaaatg atagatttaa ctttacttgg atgtggtgga aatgtaccta
    29341 tgccaaacag atttctatcc tctgtattta taaactataa aggtagaaaa atactaattg
    29401 actgtggtga aggtactcag gtatctatga agctaaaaaa atgtggcttt aaagatatag
    29461 acttgatttg tataacccat ttacatggtg accatatatt tggactttta ggacttttat
    29521 caacaattgg aaatagtggt cgtacaagtg atttaactat agttggtcca gttggaatag
    29581 tcgattgtat acgttctatg agaaatttag tagaatatgt accatacact ttaaaaatta
    29641 tagaaaaccc tcaaggcaat ttttctttag ataataaagt tttaagaaat ttagaaattt
    29701 caacaatcag tttagaacac tctatagagt gtttaggata cagttttaat tttagaagaa
    29761 accctaaatt tgatatagat aaggcaacta aaaacgaagt tcctaaaata ttatggaaca
    29821 aactccaaga aggtcaaaat atagttttag attcaaaaca atacactcca gatatggtct
    29881 taggagaatt gagaaaggga gttaagataa gtcttacaac cgatacaaga cctatagaat
    29941 caataccaga tttcataaaa gatagtgatt tatttatatg tgaagccatg tatggtgatg
    30001 atttagatat atcaaaagct gttagaaaca aacatatgac ttttagagaa gctgctaatc
    30061 ttgcaaaact tggaaatgtc aaacaacttt tactgactca ttttagtcct tctttagaca
    30121 tacctagtat gtatttagaa aatgctacta atgtttttga aaatactatc cttggagaag
    30181 atagattaag cttgcgttta aattttgatg aataatttaa tggaatcctt atttctaaaa
    30241 atttggaata aaaatttgga ataaaaattt aggaatgaat tttaccatga taaaaatagt
    30301 ttaggtaaat tcattccctt aattgcttgt caactatatt agctataatc taaatattat
    30361 ttagatacat ttccagctac atttaaaaca tcccatgttc ttgcaaatgg tggagcataa
    30421 cataaatcta acattccaag ttgatttgtg gtcatttttc caaagatagc agctgccaat
    30481 acatttgctc tttggacagc atccttaaac ccagccactt gtccgcctaa aataactttt
    30541 gtatctgcat cataaataag ctttacatat attttatttc ttcctggata ataatgagtt
    30601 tgattataat cagaaataaa tttagatttg acatttatgc ctaaatcttt agcttgcttt
    30661 tctgtaattc cagttgatgc tgcctccata tccataattt ttatacagct tgaagatagt
    30721 gaaccttgat aagatacttc tcttcctgct aggttttctc ctactatcct acccaattta
    30781 ttagctccag tagctaaagg aacatataca ttttcattac ttactatatt ctttatagtt
    30841 gcacaatctc cagcagagta tatatcttct acagaagttc ttccatactc atcaactact
    30901 atagctccat tttttagcat ttttatatta gtatttgaca aaaactcggt attaggtctc
    30961 acgccagtag caattattac tacatctgta tctatttccc ctttgtttgt tataactttt
    31021 tctactttat cttctccaca aagttctaca accatttcat ctaagtgcaa attaacatta
    31081 tgtctattta tttcttcttc taatacatcc gtcatttcct tatcaaatac ttgtggcaat
    31141 attctatctt ctaactgaat tacatctaca tctttaccta atttcttaca tgcctcaact
    31201 gcttctaacc ctataaaacc agctcctatt attgtcactc ttttattatc ttcattactt
    31261 aaaagttttt ttagatattc tccatcatat aaacttttta atgtagaaac attcttcaat
    31321 tttatgtttt ttataggagg cataatactt cttgctccag ttgctatcat caatttatca
    31381 tagtaatctt catatatttc atctgttttt atgtttttta cttttatttt cttagattca
    31441 ctatcaacct caacgacttc tctaaatata tttaaatcaa ttccagcttc tctaagtttc
    31501 tctggtgttc ttgctaataa ttcatcagca tcattaaaaa atccaccaac aaagtatggt
    31561 aatccacaag caccaaaaga tactatttca gttttttcat aaacaacaac ttcatactca
    31621 ggttttattc tttttaattt tgctgcagca ctcataccag ctgcaacacc accaattatt
    31681 attactctca ttttatctct cctttgatgt ctagttaatt tcttcactta ttttaagctt
    31741 ttcatttgat atatattcta tgaaaacatt ttttataata atttttagtt atttatttaa
    31801 catattttaa tttgaaatca aatcttataa aagctatttt ttattttctt accacaattc
    31861 aaattcttta aacatttatt ataccctatt tttctgtact taatcacatt tttcaaaatc
    31921 aacttgtttt actctattta agtaaattgt gatataatat tgacattttt ttaatatatt
    31981 gatatcattt aaacttagaa aaatttattt ttaaataaaa ggagaaaaat attggaaagt
    32041 tcatttttat cacaatttct tatgattaca gattttaaaa caattttttt cataatatta
    32101 cttctaggta cgttctttat tgttagacaa tttgaaaaga aaaaaataaa attttcattg
    32161 agaacaatat atgctacagt actaggactc atattgggaa tcataataca agcttttgct
    32221 ggttttccta atgatacaac tcaagtcact tggctacaag aagtaagtaa gtggtatagc
    32281 ctatttggtt ctggatttat ggacttatta aaaatgttag tagtaccttt agttttctta
    32341 tccattataa aagtaattat aaatatgaaa gataacaatc ttggaactct gacatttaaa
    32401 tctttaggta tgcttcttgc tactactgct atagctgcaa ttgttggaat tatcgttgca
    32461 aatataatga agttaggtgt aggagctaat atgcctactt tagttgaaaa tcaagaactt
    32521 aaagaaataa actctcttgt ggatacttta agaggattac taccatctaa tcctgtaatg
    32581 gctatggcaa atggaaatat tgtagctaca ataatatttg ctacatttat agctacctca
    32641 ataaagagat taagtaaaaa acattttgag acaataaaac catttataga ttttatagaa
    32701 gcatcttaca aaataattgt aagtgtgtct atgactgtta ttaaatttat gccttatgct
    32761 gtggttgctc tgcttgcaaa tacaataact tcacaaggta ttagttcaat agtatctgtt
    32821 ttacagttta tattagctct ttatatatca gttgcaatat tatttattat acatttaatt
    32881 tttataactt taaatggtct aaatcccatt acttatataa aaaattcaac tgaagcttta
    32941 cttctggcat ttacttcacg ttctagttta ggaacattgc ctgtaacgat agaaagtcta
    33001 gtacaaaatc acggagttga tgagggtgta tcaagcttta cagcaagttt aggtgcaaat
    33061 atgggtatga atggttgtgc aggtatatat cctgctttaa tggctgtaac acttgccaat
    33121 atggctggag taaacatgga tatgagcttt tatgttatgt tgttaattgt tataacaatt
    33181 agttcgtttg gaatagctgg tcttccagga actgctacaa tggccgtttc agttgttatc
    33241 tctggagttg gtcttggttc ttattttcca ttagttggtg gtatacttgc aatagaccct
    33301 atactagata tgggacgtac tatgataaat gttaatggtg ctatggtatc atcaattact
    33361 gtaggaaaat cacttggaaa aatagataaa gaagtattta gtaaaaaaaa tatttcttag
    33421 aataacactc aaaataaatg gctaactttt taccagttag ccatttattt tatcagaaaa
    33481 cttttttaga aatttactca caaaacggaa aaaattcttt tgtaagattt tggggatata
    33541 cagatataaa aacaaagtca tagtcatggg attttgcata ttctagtata tctccatcat
    33601 aatatctagg gtctatcata tctatagatg aacaaacaga ggaaaaaaat gctgctgttg
    33661 gtacaattag agaatcttta acaaacagca cttttaatcc atctggattt tctatatttt
    33721 ttattttaac taatggtctg ttccccaata aatatgtaaa atacttatct gattgaccat
    33781 ccattaaatc aaggtctgca ttaaaaggat atgataatat taaactctct tcaaaccttc
    33841 cttttaattc aaatttttga gatttagaat ctgtataata agtataatta gtcttaaatt
    33901 taggataaat taatgtaaaa tcatctatac caccatataa gataccagtc tttcttccca
    33961 tagaaccaag aaatgactta ggatatacaa ttgaattata attgtcctta tctctataat
    34021 aatgattttc atctaaattc atattgtatt ttttattaag ttgctcaact aattctccaa
    34081 atgcccaaaa agaagtttct actttccagt gatggtctgt tttaaaaaat aaatcatctt
    34141 ttggaatacc actctttaaa atattttctc taaaatcaat atagtccaca ttatactttt
    34201 ttagttgatt taaaaaatta tctgctgtct cattactata agaataaggt attccttttg
    34261 gaaattttgt cactcctttt atatacttat ctggagtcat taggtaaacc aatttagtgt
    34321 tttgcttttc catttcatca gaaaattttc ttaccctatc tgctatcaca ccaactggat
    34381 ttggagcttt agcaaaatat gtataatgca tctttccaga agtatctttt acaacactaa
    34441 attttgaaaa ctcattttta cccattaatt tttgtaaata gccataagtt tcaatgaacg
    34501 tatttttgta tattactttg tcattcactg tattatcaat agatgatatt gtatctttta
    34561 aactactttt ttcagctatt gaatttttta tttcctgtat cgtatctttt ccagaataac
    34621 aaacattaaa gatagagaaa gcgaataaaa taattaagaa cataattgca gttattaatc
    34681 ttactttaaa aaatctattc atacttttcc tcccaactaa aaattaaaat aaataaatgg
    34741 attatagctt ccagttacta aatatgtcac agaaataaaa aacaataaaa tagctgagat
    34801 tggataaaat acgttaaata tcatactata tttagcttgt tcaacaacaa acttattgat
    34861 tttctttgca ataggtacac taaaaataaa tgcaaatata aagaaaaccc agtattcttt
    34921 taaaaacata tatgtataat cactccatat agctccattg cctccaaaca tagctttaaa
    34981 ataattatat gcttctttta aattaggtga cctaaacaat acccatccaa aattaactac
    35041 taataaagca taaatatgtt ttataaaatt gtgattttca atcttttcaa acattataaa
    35101 tcgctctata attaggaaaa caaagtttaa aatcccccaa attacaaatg tccattctgc
    35161 tccatgccat attccagtga ataaccacac tataaacata tttctaatca taatatcttt
    35221 atttgctact ctagaacctc caagcggaaa gtatatatag ctcttaaacc acattcccaa
    35281 agaaatgtgc catcttctcc aaaactcact aattgatttt gatatatatg gataattaaa
    35341 gttctcttca aatttaaaac caaacataag acctaagcct atagccatat ctgaataagc
    35401 agaaaaatca aagaatattt gcagagtata ggctattgaa ccaagccatg caagtgatgc
    35461 agctatttct ccttgactat tcatagtgta aatatagtct gctactatag ccatgttatt
    35521 tgaaattaat acttttttac ctagacctgt tatgaacctg caagtaccaa tagaaaattt
    35581 attccaagtt tcttttctat tgagaatttg ttctgccaca ctctcatatc taactatagg
    35641 acctgctatt aattgtggga aaaatgctat atacagtccc acataaaaag gattcttttg
    35701 gacttctcca tgtctacgat atacatctat aacataagac attccttgaa atgtaaaaaa
    35761 tgaaattcct ataggtaaaa taatattagg tatagtcaat tcagtactaa taagttcact
    35821 aatatttctt agcgcaaaag ctagatattt aaatataaat aaaacaccta tattgtatgc
    35881 acacatcaaa actaaaaaaa cttttacttt tattttactt tccctatatc tatctaccag
    35941 taaaccaaat atatagttca ttattatgga aactatcatg ataacaacaa attttggctc
    36001 tccccaagca taaaaaaata aactaacagc aagcaatatc atgttctgta tcgttcggtt
    36061 aaacctaaat acataatata aaaccaaagt tataggtaaa aaataaaata aaaaaattaa
    36121 acttgaaaat aacacaatct aacctcctct ctttacttag tttttgaaca ttttttccaa
    36181 tataaatata ttccaaagca tattattact agagatacaa ataaaattcg aacaaacgtt
    36241 atgatattat tcataaaatt tatttttttc atatcttgta ctgttggtga ttgctcagga
    36301 gatactaatg tatatggaac accatcctta tcttttttat taatactcca agattcagtt
    36361 aatgttattt tctttccaat tttaaactta tcatcaacat taacttgtaa aataatttgt
    36421 ccaggtttgg ctttattact taatgttaat ttaccgtttt gagatatact cacattatct
    36481 tgttttccca taagagagta cttaatttta gaatcacttt taagacctaa tacctcatac
    36541 tgacttatac tttgacccaa tactggtatt tgtacttctt catcgccaat tattttaata
    36601 ttatttaaaa atcttaattt ctcttcagac aataaagata tcttttttat aataacaata
    36661 ttatgttctt catcagatgg aataaacgta attccccaac taacaatgtt tgaaagcata
    36721 tttgagtcca gcacaacatt actttcctca tttataaggc tattaaagtt cacataaatt
    36781 ttgccttcaa attcacctgg tacttctatg catccttctt ttattttatc tgaatatatt
    36841 atatttttac cttctaaaaa tacttcacta ccttctttta atctaaattc aagcatattt
    36901 ttactttgta tgcttaaatt tat
//
LOCUS       DAEPHU010000040        34861 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 01A10CD0081
            SAMN05941466-rid12468953.denovo.040, whole genome shotgun sequence.
ACCESSION   DAEPHU010000040 DAEPHU010000000
VERSION     DAEPHU010000040.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941466
            Sequence Read Archive: SRR6291087
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 34861)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 34861)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068158.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 22:43:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,892
            CDSs (total)                      :: 3,805
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 87
            rRNAs                             :: 8, 1, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 55
            CDSs (without protein)            :: 55
            Pseudo Genes (ambiguous residues) :: 0 of 55
            Pseudo Genes (frameshifted)       :: 21 of 55
            Pseudo Genes (incomplete)         :: 28 of 55
            Pseudo Genes (internal stop)      :: 16 of 55
            Pseudo Genes (multiple problems)  :: 8 of 55
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..34861
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941466-rid12468953.denovo.040"
                     /strain="01A10CD0081"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            complement(69..716)
                     /locus_tag="KR231_002087"
     CDS             complement(69..716)
                     /locus_tag="KR231_002087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01906 family membrane protein"
                     /protein_id="HBH0004455.1"
                     /translation="MKKFLNVLFSICISIVIIVGVINFTVGFKQLYYFDIDYLNISEL
                     SGLSKDDIKLNYDYLIDYNLNKNVSEFKLPTLKSSPQGKIHFEEVRNIFQNINKLAKL
                     LLVVSLVGIILSVKNKNIKILKTTSITLIIMPLLLTVPILLNFEKSFIIFHKLLFRND
                     YWIFNPDLDPVINILPEEFFFHSGMMILILILLVSIVLFVMYKLCKSLSIKIFQC"
     gene            complement(745..2295)
                     /locus_tag="KR231_002088"
     CDS             complement(745..2295)
                     /locus_tag="KR231_002088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018592108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HBH0004456.1"
                     /translation="MLVVENVSHGFGARTILENVSFRLRKGEHIALVGANGEGKSSFL
                     NIITKKLMPDAGNIKWSSRATVGYLDQHTVLSKGKTIREVLREAFKHMFDLEQEMIAM
                     YDKMGEASDDEMSKLLEETAEIQTILENSGFYMIDAKIQEVANGLGLGEIGLDKDVTD
                     LSGGQRTKVLLTKLLLENPTILILDEPTNYLDEEHITWLTKYLQEYENSFVLVSHDIE
                     FINNTCNVIYHMENGELNRYKGNYDEFVRLNDIKKRQEEQAYDKQVEERKRLEDFVAR
                     NKARVATRGMANSRQKQLDKMEILERPKEKIKPTFAFKDARAASKIIFETENLVLGYD
                     EALTKPLNFHLERGKKIALKGMNGIGKSTLLKTLLGIIKPFEGNVKLGDYLEVGYFEQ
                     ESSRENSNTPMDEVWSEFPGLTNFEVRQALAKCGLTNEHITSQMRVLSGGEAAKVRLC
                     KVMLKNINFLVLDEPTNHLDVEAKDELKKAIKEFKGTVLLVCHEPEFYSEIVDDVWNI
                     EDFTTKIV"
     gene            complement(2497..3381)
                     /locus_tag="KR231_002089"
     CDS             complement(2497..3381)
                     /locus_tag="KR231_002089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HBH0004457.1"
                     /translation="MKKYRLLVTCIIAMGIIIIGTSNPVSNFYKTTNLISSGNITNEK
                     ANKDENSNKNNKDKNEDKSNSKSNKDKSSEDKSSDNKNEIQKNKKLLICIDPGHQGKG
                     DSNLEPVAPGSSSKKARVSSGTEGIATKKPEYVLNLEASLVLKSILESKGYNVIMTRE
                     THDVNISNSERAILANDKKADMVVRIHADSLNNSSKTGASILIPEKDGKYTAPIYEES
                     NKCAEFIKQNMEQSGIQINGIVQRGDLTGFNWSKVPAVLVEMGFMSNYNEDQMMSNPD
                     YQRKMMQCIADGLDAYFK"
     gene            3609..4622
                     /locus_tag="KR231_002090"
     CDS             3609..4622
                     /locus_tag="KR231_002090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888579.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase S55"
                     /protein_id="HBH0004458.1"
                     /translation="MQLKNFHFKNNTLSKKTNLAKSKFTIVLTFLFLFLLYFFSNNLI
                     YAQNLQKNEPEYLIPIGNVLQIDAELKNIIVRNPGEASPFRLGDAIVKVNNAEVDGYS
                     DFANTLNALPEEKQVSILLNRGGQLITMKTTKHILEKISFNNLLSGFATLTYINPDTS
                     EFGAVGHPISVGNARKIPIKTGSISTTKHLNIEKSYKGSVGCINAKRENIIGSFTENT
                     DFGIRGQINNFDISKLKKYKVASLDEVKLGKAQIILQDNFNKCKKYNIEIIDIENQKH
                     PESKSFKIKITDKKLLAQTGGIVQGMSGTPIVQDNKIIGAVSHAIENDPAVGYGVFIK
                     WML"
     gene            complement(4838..5536)
                     /gene="yunB"
                     /locus_tag="KR231_002091"
     CDS             complement(4838..5536)
                     /gene="yunB"
                     /locus_tag="KR231_002091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sporulation protein YunB"
                     /protein_id="HBH0004459.1"
                     /translation="MNRIVDRKTKNEFRKIIAIFLVILFLSVFIGSFIYIDKTLRPTI
                     TVLAETKALELANRSINKAVAEMVEGKINYEDLMDIQLDNNGKITMIQANTIMMNEIA
                     SAIALEIQDELKKDKTASSYIPIGTALGSPILAKYGPKLEVSIEPIGTVSVNFKTEFE
                     SSGINQTRHRIYLEAQTQVKVVIPLITSTKQIKAQIPICETIIVGDVPESYVNIPEKN
                     LGNVLPNTGKNTNK"
     gene            5750..8443
                     /locus_tag="KR231_002092"
     CDS             5750..8443
                     /locus_tag="KR231_002092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transglycosylase domain-containing protein"
                     /protein_id="HBH0004460.1"
                     /translation="MNNDNDKNGNKIRRKKVSSSGNTNKPINRTSANKTRSTKNKKKS
                     KKSDKFKKLRVFGIVFLVLLVVGTAGTAGLVFASLRDVTPVTEAVLDKQTNQTTTIKY
                     ANGKTLSTAPSVNKKTPVPLDKISPYLQHAVIAIEDERFYEHKGVDIKGLFRSVLKTL
                     TGTKQGGSTIPMQVSKMLLTTEQQTIPRKIKDIYYAHEMSKTVSKDKILETYLNNFFV
                     GRGLAGAEAGARGYFDKSAADLTLAESALLAGSTKNPSRFSAYKTSKLEGNETKEDLE
                     NKLLFFVNTTDDDLDDPTQVDFDMIEKIKSWELISNDTYRQLKAGTLVVRKAVSNPEA
                     KKRQEIVLKKMLELKYIKQSEYDEAIKAKIEIKLPQSSDKVSSSVEDLIESEVINALM
                     EQGHTNDEAQNLFYNGGLIVNTTIDPKMQDALEEEFDRNSNFPGHMVGPDGVSQPQAA
                     MVILDYKNGEIRALAGGRNISGRKTLNRATNPHQPGSSIKPLAIYTPAIDTLKITQAT
                     ALSDSRGGYKFKENNEWNPRTTTAGHGSMSLRKALAKSSNTIAVKTAEMLGDSYDECV
                     DIMMDYLKNFGITTLKNNHSGSSEASDRKFPSLTLGGMANGITPLQMAAAYGTLANHG
                     IYVEPSIFTTITTFDGQLLVKNAPEEHKVVDPEVAYVVTDMLESVITEGTGGVATLPK
                     GMPVAGKTGTTNSAYDAWFVGYTPYYVGATYIGDDAGRKDDSGNTIKRREVPHGSTST
                     AKLWEKIMEKIHANLTVTEFEVPKNVYFTKINLEDGGKQSSGSKAAFIEGTAPTKVSS
                     QPSSEDTKKPDNNQPEENNNNNNNTGDNGGGSTPPDNGGNNGGGSTTPPDNGGNNGGG
                     STTPPDNGGNNGGGSTTPPDNGGNNGGGSTTPPDGGGTPAT"
     gene            complement(8717..9652)
                     /locus_tag="KR231_002093"
     CDS             complement(8717..9652)
                     /locus_tag="KR231_002093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1177 domain-containing protein"
                     /protein_id="HBH0004461.1"
                     /translation="MILKQVIEVYDILDKANANGEEVKTYLQGYGEVDVTVKELSSSK
                     GSTDLVKLTIPGKNGKLKGGDAPTLGILGRLGGIGARPEVIGFVSDGDGALVAIAVAA
                     KLLDMQRKGDILDGDVVISTHICPDAPTKEHYPTPFMDSPIDMMTMNENEVDSSCDAI
                     LSIDTTKGNRVINTRGFAISPTVKEGYILKTSDNLLDIMQTVTGKSPFVFPLSIQDIT
                     PYGNNLYHLNSILQPAVATDAPIVGVAITTEMPVAGCATGATNFSDLDSAGRFAIEVA
                     KLFGRNKCDFYDKEEWEMLIKRYGKLNRFQTFGIQ"
     gene            complement(9696..10868)
                     /locus_tag="KR231_002094"
     CDS             complement(9696..10868)
                     /locus_tag="KR231_002094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallopeptidase"
                     /protein_id="HBH0004462.1"
                     /translation="MECFKEVVNMNELKAKIKEEIKLLSEEKKTSFEKVSDYLFSNPE
                     LAFEEYKSQKALCDLLEENEFNVTKGVGGLETSFEAVYSNGTNGKTVAFLAEYDALPG
                     MGHACGHNIIGTSSVGAGIILKEIMKKHNIEGTVKVFGTPAEERVGGKITMIKEGVFN
                     NVDAALILHPSDASMPDDISFAQVNLKFDFTGKASHAAAFPWEGKSALSGVIALFNSV
                     NSMRLHLKDYARVHGIITDGGSIHNIIPEKSTAIFNVRALSIEYLNEICEMLKNCAKG
                     AAISTGTNVEIVQLDEIYKEIKNDSELVNIVRQNFEVLGEDYVERDLSQGIGSTDTGN
                     LTHEIPAIQAYIKLKENTATHTDEFAVAAGGEEGRVALIKAIKVLAMCGVDILYSK"
     gene            complement(10855..11319)
                     /locus_tag="KR231_002095"
     CDS             complement(10855..11319)
                     /locus_tag="KR231_002095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0004463.1"
                     /translation="MEKTFKTIMEQIKIVLFIYIIICFGQMIALKTQAQDLLIGSVSG
                     FLLVIIAIIIKNFVKKPNLPGFAWATLVAFVLSLPISPVGDIIATNVGKINFMSTVTP
                     LLAFAGISVGNQLDILKTLSWKLVVISFIVMTSTYFGSAFISQTVLRLNGML"
     gene            complement(11334..12176)
                     /locus_tag="KR231_002096"
     CDS             complement(11334..12176)
                     /locus_tag="KR231_002096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3100 domain-containing protein"
                     /protein_id="HBH0004464.1"
                     /translation="MKEKAGIRNAIIAAFIITILAELIGPISFKVMGINVTLLSILWA
                     IFIGMAVSPHLLGRVIPALKKFIGDNEINVSPYLLSLTLYPLGIMFGINAGPKVGILL
                     QAGPALLLQEFGHMGTMLIALPVGVALGLGRSALGGTFSLCRDTALGIIGDKYGLNSP
                     EGIGTLGTYISGSIFGTLLFSFLAPVGVLLGFHPYALAMASGMGSGSMMGAATASLMN
                     TVPQMSEQILAYSATSGLITAVTGIYIELFLSLPVANYYYSKVAPVIERFRGRKTRRT
                     SNKL"
     gene            complement(12551..13567)
                     /locus_tag="KR231_002097"
     CDS             complement(12551..13567)
                     /locus_tag="KR231_002097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HBH0004465.1"
                     /translation="MVTIKDIARNLGISYSTVSRCLNNNPNVSEKTKKKVVEEANRLG
                     FHFNVNARNLAKKETNRIGVIFSNNFNHQDTRKFFSDIMDSSINSIETNKYDFIIQPN
                     NNISGDSNVYKMVNGQMVDGLVIVSQSIKKEEYDFLKDNNFPHVFIYFKPSFIGEVDN
                     FFWDDNVYGGYIATKHLIDHGHKDIITVTSDDKSSKMHEDRTKGYLNAMEEANLKTEV
                     IKSKMDFESQVEFLEKYIDKIKKASAIFVQQDVPAISIIQELKTTYGINVPEDISIIG
                     YNNIELISYFRSHLSTIDDPREQVIKNGVDSLVNIINKKSTEHIPRKLYPRLIIRNSV
                     KRIK"
     gene            complement(13750..14112)
                     /gene="spoVAE"
                     /locus_tag="KR231_002098"
     CDS             complement(13750..14112)
                     /gene="spoVAE"
                     /locus_tag="KR231_002098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage V sporulation protein AE"
                     /protein_id="HBH0004466.1"
                     /translation="MLMDYVRVFIVGGIICLIAQVMMDYFKMQTPYVMVTYVTTGVVL
                     TFLGLYEPLVKFAAAGATVPIIGFGYSLATGVIKSIQSDGFLGIFLGGTTATAGGIAA
                     AIFFGYIMSVVFTPKAKP"
     gene            complement(14126..15139)
                     /gene="spoVAD"
                     /locus_tag="KR231_002099"
     CDS             complement(14126..15139)
                     /gene="spoVAD"
                     /locus_tag="KR231_002099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage V sporulation protein AD"
                     /protein_id="HBH0004467.1"
                     /translation="MKNKRIGKRTVKLENKPTIISTGTIVGPKEGEGPLKDYFDMIMT
                     DDLYGEKTWELAESKMVETASQQAIQKAGKKLSDVNYMLGGDLINQIVPASFAARELA
                     IPFLGIYGACSTMAEGLCIGSMLIDGGFADLVLSGTSSHYCTAERQFRFPLELGNQKP
                     MTAQWTVTGAGSVLLAPNGDGPKVKYVTVGKVIDEGIDDGNNMGPAMAPAAIDTIYSY
                     FEDTNDDPNSFDIIATGDLGTLGKQIAEDFLKEKGVDISKVYTDCGIEMFNLKEQDVH
                     CGGSGCGCSATVFAGYIYDKLRKKEFNKVMLVSTGALLSPTSTLQKQTIPCVAHAVVI
                     VNE"
     gene            complement(15306..15743)
                     /gene="spoVAC"
                     /locus_tag="KR231_002100"
     CDS             complement(15306..15743)
                     /gene="spoVAC"
                     /locus_tag="KR231_002100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage V sporulation protein AC"
                     /protein_id="HBH0004468.1"
                     /translation="MDKNYKKYVDQISPKPTYLKNYTLAFIVGGIICMIGQAINDLYM
                     KVGGLDKLGASSATSITLIFIGAFLTGLGVYDLIGKRAGAGSIIPITGFANSIVSPAM
                     EYKREGYVLGVGANLFKIAGPVLVYGIGSSILCGIIYYIFKMF"
     gene            complement(16023..16787)
                     /gene="sigF"
                     /locus_tag="KR231_002101"
     CDS             complement(16023..16787)
                     /gene="sigF"
                     /locus_tag="KR231_002101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sporulation sigma factor SigF"
                     /protein_id="HBH0004469.1"
                     /translation="MEVTVAREEKKPLLSHEETLELIEKVQNGDEEAKEILISSNLGL
                     VRSVVSRFLNIGYDREDLFQLGSIGLIKSIYKFDPKFNVKFSTYAVPMILGEIKRYLR
                     DDGMIKVSRSLKQIAVKAKMESEALTKKLGREPSIEELAKAIDVEKEDLVMAMEANFN
                     VEYLQGVIHEEEGSPICLIDKISMKGESEEEKVVDNILLKDILGRLDKRERQIIVLRY
                     FEDMTQSEIGEMLNISQVQVSRIEKKVLSKLKEYIS"
     gene            complement(16810..17238)
                     /locus_tag="KR231_002102"
     CDS             complement(16810..17238)
                     /locus_tag="KR231_002102"
                     /EC_number="2.7.11.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anti-sigma F factor"
                     /protein_id="HBH0004470.1"
                     /translation="MNNIMEVKFSAISENESLARVIVASFAAKLDPTVDELVDIKTAV
                     SEAVTNAIIHGYEEDSSKFVFLRCEIEGNTIKIIVEDEGYGIENVEKAMEPLYTSKPE
                     LDRSGMGFTVMKSFMDDVEVSSVKDNGTRIEMTKKINVPK"
     gene            complement(17252..17587)
                     /gene="spoIIAA"
                     /locus_tag="KR231_002103"
     CDS             complement(17252..17587)
                     /gene="spoIIAA"
                     /locus_tag="KR231_002103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anti-sigma F factor antagonist"
                     /protein_id="HBH0004471.1"
                     /translation="MVNYSLEHKNLYIEFMCSELDHHVANEIREEIDNLLSVNQVKNV
                     VFNFENINFMDSSGIGVIIGRYKKISNEGGRVSVINISSRVKKIFDLSGLNKIIGIYD
                     TYEEALSSL"
     gene            complement(17675..20113)
                     /locus_tag="KR231_002104"
     CDS             complement(17675..20113)
                     /locus_tag="KR231_002104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdopterin-dependent oxidoreductase"
                     /protein_id="HBH0004472.1"
                     /translation="MDIIKKLSHGCTLDCHDCCKFNVYTKGNNVVKIEGDKNHPYTKG
                     FICKKGMAHLDRLNHKDRIKTPMLKVDGVWKEISFDKAIEIMAEKLTYYKEKYTSKSV
                     MHYDQYGSGSVLKYIGDIFFNFYGGVSRHKGGPCWSAGMHAQKYDFGVAKSHAIEDML
                     NSKSIFVWGKNPAYTTIHTMQIIKKAKEKGIKIVVIDPIYTKTAQIADKYVQVNPGTD
                     GALAIAMAKIIVEDKLYDEEYINSYVIGFEEYKKYLSSLELSFLIDECGVKENDIREL
                     VDLYTNKYSSINVGYGLQKYKNGGNTIRAIDALGAITGQIGFSGGGVNYANKVYPSVI
                     NSDPYNSQSYGEDREFYVSNISKFIEESLKNTSNKVNYASDELDMALHKVNYISDELD
                     TTSNKVNYVSDELDMALHKVNYVSDELDTTSNKVNYVSDELDMALHKVNGVSDELDMA
                     LHKVNCVSDELDMTSNKVNYVSDELDMTSNKVNYVLDELDITSNKTDYISNELYNLSN
                     KSIKDNIPIKMAVITKSNMLNQLPDLVELERVFSKIEFKVCFDMFITDTVTLCDMFIP
                     CTNTLESEDIIYSSMTNPYITYNERAVKPAHKLMDEYYFFMELAKKMGLNDYPFVEKR
                     TYLEKVIEPLKRFDKNLDIEKLKNNYFTIHNPVAWEDKKFETPSGKYELYSESIKNLG
                     ISPTPVYISNKYKEIEDKNISFRLLTNHHADTLFSQHFMDKKSIAQAYINQRMAKKVG
                     IEEKDIVILRSKKAKINVQINIDDGVGNYIVKMYVGWWKKHGNPNSLTDTGISDFGGQ
                     VTYNESMVEIIRQN"
     gene            complement(20462..21235)
                     /gene="srlD"
                     /locus_tag="KR231_002105"
     CDS             complement(20462..21235)
                     /gene="srlD"
                     /locus_tag="KR231_002105"
                     /EC_number="1.1.1.140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sorbitol-6-phosphate dehydrogenase"
                     /protein_id="HBH0004473.1"
                     /translation="MRKVALVVGGGRSLGEYLSKHLAKVGYDVAIADLNEDNAKKVAE
                     EIKTEFGCKSVGYSCNAIDERQVISTVKAIENDFDRIDLLVYNAGVAVSKKITDFGYK
                     DFKFIVDVNLNGYFLFAREVSKVMIAKGIEGRIIQINSKSGRVGSKHNSGYSAGKFAG
                     VGLTQSLALDLAEHKITVNALMLGNLLDSDMFESLIPQYAVKLGIPESEVKQVYIDKV
                     PLKRGCRFIDVANMLTFYASKEAEYCTGQSINITGGQVM"
     gene            complement(21336..21701)
                     /locus_tag="KR231_002106"
     CDS             complement(21336..21701)
                     /locus_tag="KR231_002106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIA"
                     /protein_id="HBH0004474.1"
                     /translation="MELIYSTQINKIGDNANEFLQHNMFVTFKDNAPQELENYCYIHS
                     ENNLVKEILTDDVLSINNVDYKITSVGELVNQNLSELGHITFKFTGEKDGAIGGTLYL
                     EEKEIAPIGVGTILKIIRK"
     gene            complement(21742..22701)
                     /locus_tag="KR231_002107"
                     /pseudo
     CDS             complement(21742..22701)
                     /locus_tag="KR231_002107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006565779.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIB"
     gene            complement(22765..23325)
                     /gene="srlA"
                     /locus_tag="KR231_002108"
     CDS             complement(22765..23325)
                     /gene="srlA"
                     /locus_tag="KR231_002108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418408.1"
                     /note="catalyzes the phosphorylation of incoming sugar
                     substrates along with their translocation across the cell
                     membrane; the IIC domain forms the PTS system
                     translocation channel and contains the specific
                     substrate-binding site; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIC"
                     /protein_id="HBH0004475.1"
                     /translation="MTQFFQVLASGADSFMNLFRAGGQQFVGFVTDIVPLLVALLVTM
                     NAIINFIGTDRVERLAKKCSANIFTRYLILPVLGTFVFANPMTLSLGRFLPEKFKPSY
                     FAAASFSCHTMNGLFPHINPGELFIYLGIANGITTLGFSTADLAVRYLLVGIVANFIK
                     GVVTDYTTKFVEKQQGIALNSDIKIG"
     gene            complement(23354..23788)
                     /locus_tag="KR231_002109"
     CDS             complement(23354..23788)
                     /locus_tag="KR231_002109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator GutM"
                     /protein_id="HBH0004476.1"
                     /translation="MDPVIFIIASLITVYLLNIFLGYLQLKDFNKNYIELKRKGRVAI
                     GRKKGRISSGTIVLILINDDGVIVETRKMQGVTVLARVKSFEGLVGKSLEYIEKSDLT
                     VYNKLLKKAILDAVKQYITFEKNKCEDTNNLSTDEECRMEVV"
     gene            complement(23793..25778)
                     /locus_tag="KR231_002110"
     CDS             complement(23793..25778)
                     /locus_tag="KR231_002110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860951.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HBH0004477.1"
                     /translation="MSMTYMDPRVFLILEMVLEEDTNTLEQFSNVLGVSTRTIRNYIN
                     QINRELKGGIAKIVKNEKGTYSIRIEDESKLIEIVNFNRGKLSNFINLNSPDERINYV
                     LDILTMTNNPITIDDLAEEICIGRTTLIKDLKKADRILAEYDLELKRKPNIGMILVGE
                     EMDIRLLILDRLYENYIDVLENVNQINLVKDYDIECLRDELKKLFKKEELYITEQVLR
                     DVERYIIMSVLRNLNGYKFEKIDKRFEVIRCSDEYTLGLKLKALLEKIFNIVLNEKET
                     IFLTMPLIGRKAPSTKLALSSIKINDSVKEVVDEVTSFLLETSGIDFKEDKKLIENLE
                     YHLYFALNRMRFNIRVKNPLLQEIKERYTFPYSVAKIAAMIIEEKFDLKICDHEIGYI
                     ALHFGSYFEKNSRKVLNVNRVAVVCGTGLGTAQLIRIKIGKILGESVEVNTFSDIEAK
                     ANLDLLKYYDLVFTTVDFKTDLDVPIFRVNALFNEESIKKEIENAILLKNSINLKSIK
                     KIEKNIPFIGKLIEEDKFFILNKSTFMENLEDMLEKLVHKGIIDIEFKKKVLKREKKS
                     STALDNYIALPHSVNTNGENLYLAFGILEKPVIWDTKEIRIIILMIIPDKNVDSTDLI
                     IKSYEEVLEVGRDKKMVEELAKVKSFDEFYKIITKRR"
     gene            complement(26053..27666)
                     /locus_tag="KR231_002111"
     CDS             complement(26053..27666)
                     /locus_tag="KR231_002111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HBH0004478.1"
                     /translation="MNITKFEDLPISEGIKKAIAEMGFEEPSPIQAQSIPAILSGKDV
                     IGQAQTGTGKTAAFSIPILETIDPNNRSLQAVVLCPTRELAIQVSTEIRKLAKYSHGI
                     KTLPIYGGQPIDRQIKSLKSGVQVVIGTPGRTIDHINRKTLKMDNVKMIILDEADEML
                     DMGFREDIEMILSKIPEERQTTFFSATMPRGILELTKRYQKDPEHIKVVRKELTVSNT
                     KQYYIETRSSNKLEVLCRLVDVYDPKLSVVFCNTKRKADELVGDLQARGYFADALHGD
                     LKQTQRDIVMDKFRNGTIDILVATDVAARGIDVDDVECVFNYDLPQDEEYYVHRIGRT
                     GRAGREGMSFTFVFGKEMRKMKDIERYTKSKLIKHNIPTITDVEEKKVGTFFAQVKQT
                     IEEGHLTKQLQWLEGFCNDEDYAMVDIAAALVKLSLGEEMKEEIIEEKPRRERGDRKG
                     GTGAKDGMIRLFINIGRNQRVQAKDIVGAIAGEVGIPGKVVGTIDIYDKYTFVEIPKK
                     DAKTVIEKMKDIKIKGNKINIEKANKKKK"
     gene            complement(27757..28818)
                     /locus_tag="KR231_002112"
     CDS             complement(27757..28818)
                     /locus_tag="KR231_002112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="calcium/sodium antiporter"
                     /protein_id="HBH0004479.1"
                     /translation="MEKRKSIHLHKLNIYLIGGGDRLFITVVLFLVGFLLITKGADIF
                     INCTVEIGKKTNISEIILGATIVSFATTLPEFTVSLLASIDGHTTMSLGNAVGSIICN
                     TGLALGLVVFISPFNVDKKMFFSKSLLLIVSVIVLILLSLDGVITRGDSLLLIIILIF
                     YMVNNYRSVVGKSDTKNRNIKNNTIKDISTKKGKNYRGFSVLEIVKILLLFATGLIMM
                     IIGSQILIESGVIIASFLNIPQGIVSLTIIALGTSLPEIVSSITAIRKNHHEISVGNI
                     LGANILNIVSVIAVSAIPNNIPILSQNRQLDIPFMILLLLIVIIPTLKSNRLSRIQGI
                     LMLFTYFLYISILYFMYII"
     gene            29111..31342
                     /gene="pflB"
                     /locus_tag="KR231_002113"
     CDS             29111..31342
                     /gene="pflB"
                     /locus_tag="KR231_002113"
                     /EC_number="2.3.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate C-acetyltransferase"
                     /protein_id="HBH0004480.1"
                     /translation="MNAWQGFKTGRWTKEINVREFIQLNYSPYEGNDSFLAGATENTK
                     KLWDEAMVLFKKERENGGTLDVDTKTVSGIAAYAPGYLDKELETIVGLQTDAPLKRAV
                     MPYGGIKMVENSCEAFGYELDPEIKDIFTKYRKTHNQGVFDVYTPEMRAARKSGIITG
                     LPDAYGRGRIIGDYRRVALYGVDALIEDKNEQKKSLEVSCMDEEVIRLREEITEQISA
                     LNELKKMAESYGFDISKPATNSKEAVQWLYFGYLGAVKDQNGAAMSLGRTSTFLDIYF
                     ERDLKAGIVTEEELQEYMDHFVMKLRMVKFLRTPDYNNLFSGDPTWVTECIGGMGIDG
                     RTLVTKNSFRMLNTLYTLGPSPEPNLTVLWSTKLPQGFKDFCSKVSIDTSSVQYENDD
                     LMRAYWGDDYGIACCVSAMRIGKQMQFFGARVNLAKTLLYAINGGVDEKSGVQVGPRF
                     EPITSEYLDYDEVMSKFEPFTDWLATLYVNTLNVIHYMHDKYSYEALEMALHDRDIFR
                     TMACGMAGLSVCADSLSAIKHAKVKTIRNEQGIAVDFEIEGDYPKYGNNDDRVDSIAV
                     ELVESFMNKIRKNKTYRNSYPTQSILTITSNVVYGKKTGNTPDGRRAGAPFAPGANPM
                     HGRDTNGALASLSSVAKLPYEHAQDGISNTFSIVPAALGKDMTERINNLSAMMDGYFA
                     QNAHHLNVNVFDRATLEDAMEHPEEYPQLTIRVSGYAVNFIKLTKEQQLDVINRTFHG
                     KMA"
     gene            31502..32236
                     /gene="pflA"
                     /locus_tag="KR231_002114"
     CDS             31502..32236
                     /gene="pflA"
                     /locus_tag="KR231_002114"
                     /EC_number="1.97.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate formate lyase-activating protein"
                     /protein_id="HBH0004481.1"
                     /translation="MIKGKIHSIETFGTVDGPGIRYILFFQGCPLRCKYCHNRDTWDI
                     KSGKEYTVDEIITDALKYTSFMKFSGGGITASGGESTLQPEFLSELFKKAKENDIHTC
                     LDTSGFVDIETIDPVLDNTDLVLLDLKHMVEEKSIDLTGVGMDKALKLARHLESRNIP
                     VWIRHVLVPGITDDIDNLEKLGQFVATLKNVERFELLPYHSMGIHKWESLGIDYELKD
                     VPDATKEDVQKASEIISKFGVKVYNS"
     gene            complement(32358..34028)
                     /locus_tag="KR231_002115"
     CDS             complement(32358..34028)
                     /locus_tag="KR231_002115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GGDEF and EAL domain-containing protein"
                     /protein_id="HBH0004482.1"
                     /translation="MREESNSLSLDHIEIFFELLSQSTEDYIFFWDINRNKFKISSAI
                     FDEFNLSKEIESDLVNCWSKIVYPDDVQIWKDDIQELLHGKKGEHNLEYRLINKYKEI
                     VWISCRGKVYVSDDPKTIFLVGRIKNIGEKNKFDSITGTWNREQFEHKMNYLIKEKIY
                     KNGAMFIMDIDNFKNINEKYGHSYGDKVLRAIATEVLEYLPKDVRLYRLDGDEFAFFY
                     PMCTKETIEKIYEKIQMYTNTQHEIESSKYYCTVTAGVAMYPEDGDNYLDLFKHADIA
                     LDIAKISGKNRIKFFSQELYENKLKVISMQQKLRECVENNFNDFELFFQPQVNAVTKE
                     VIGAEVLLRWHSSTYGEVSPVEFIPILEQSNLIIPVGKWIIKEAVKQCKEWHKINPDF
                     KISVNVSYIQLKEDFFRDFIVECLVEYQLRPEFLILELTENCWIPDINLLNDKFISLK
                     GIGVYIAIDDFGTGYSSLNYLKELSVNIIKIERSFVKNITYNSYEYTFLEYIIKLAHI
                     INLKVCVEGIESYEEYDIVKSLGVDIIQGFLFGRPVSASEFYKFQLSK"
BASE COUNT        11510 a         5960 c         4113 g        13278 t
ORIGIN      
        1 tttattgtat aacttttaat ctaatccttt tttattatct tattttggaa ataaaaatat
       61 ccctctattt aacattgaaa tatttttatt gataaagatt tacataattt atacattaca
      121 aacagtacta tacttactaa caaaattaat attaaaatca tcattccaga gtgaaaaaaa
      181 aattcctctg gcaatatatt tataactggg tctaaatcgg gattaaatat ccaataatca
      241 tttctaaata ataatttatg aaaaataata aatgactttt caaaatttaa taaaattgga
      301 actgttaata ataatggcat aattataagt gttattgatg tagtttttaa gatttttata
      361 tttttatttt ttacactcaa tataattcct actaaagaaa ctaccaataa taatttagct
      421 aatttattta tattttgaaa tatattcctg acttcttcaa aatgtatctt cccttgtgga
      481 gaagatttta atgttggtaa tttgaactca gacacattct tatttaagtt ataatcaatt
      541 agataatcgt agttcaattt tatatcatct ttagataaac cagataactc tgatatattt
      601 aagtaatcaa tgtcaaaata ataaagttgt ttaaatccaa cagtaaaatt aataacacct
      661 actattataa caatactaat acaaattgaa aaaagtacat ttagaaactt tttcatgaaa
      721 tccccccagc aataagttaa atcactacac gattttagtt gtaaaatctt ctatattcca
      781 tacatcatca acaatttctg aataaaattc tggctcatga catactaaaa gaactgttcc
      841 cttaaactct ttgatagcct tcttcaattc atcttttgcc tcaacatcta aatgatttgt
      901 aggctcatct aatactaaga aatttatatt ttttaacatt actttgcaaa gtctaacctt
      961 agcagcttct ccaccactta atactctcat ttgactcgtt atatgttcat ttgtaagtcc
     1021 acattttgca agagcctgtc taacttcaaa gtttgtaagc cctggaaatt cactccaaac
     1081 ttcatccata ggtgtattac tattttctct tgaactctct tgttcaaaat atccaacttc
     1141 caaatagtca cctaatttaa catttccttc aaatggtttt attattccaa gtaaagtttt
     1201 taatagagta gattttccaa taccattcat tccttttaag gcaatctttt ttcctctttc
     1261 taaatggaaa ttaagtggtt ttgtcaatgc ttcatcatac cctaaaacta aattttctgt
     1321 ttcaaaaatt attttactag ctgctctagc atctttaaaa gcaaaagtag gttttatttt
     1381 ttcttttggt ctttctaata tttccatctt atcaagttgc ttttgtctac tgttagccat
     1441 tcctctagtt gctactctag ctttatttct agctacaaaa tcctctagtc tttttctttc
     1501 ttcaacttgt ttatcataag cttgttcttc ttgacgtttc tttatatcat taagtcttac
     1561 aaattcatca taatttcctt tatatctatt taactctcca ttttccatat gatatattac
     1621 attacatgta ttatttataa attcaatatc atgagaaact aagacaaaac tattctcata
     1681 ctcttgaagg tacttagtaa gccatgttat atgctcttcg tctaaatagt ttgtaggctc
     1741 atccaatata agaatagttg gattttcaag tagaagttta gtaagaagta cttttgttct
     1801 ttgccctcca cttaagtcag ttacatcttt atcaagacca atttctccaa gaccaagacc
     1861 atttgcaact tcttgtatct ttgcatctat catataaaaa ccactatttt caagtatagt
     1921 ttgtatctct gctgtttctt caagaagctt actcatttca tcatcactag cttctcccat
     1981 tttgtcatac atagcaatca tttcttgctc taagtcaaac atatgcttaa aagcctctct
     2041 aagcacttct cttatagttt ttcccttgct taataccgta tgttggtcta agtaacctac
     2101 tgtagctctt gaagaccatt ttatatttcc agcatctggc ataagcttct ttgttattat
     2161 atttaaaaaa ctcgattttc cttctccatt agcaccaact agtgcaatat gttcaccttt
     2221 tctaagtcta aaggatacat tttctaatat tgttctcgca ccaaatccat gactcacatt
     2281 ttctactact agcatttcaa cacctctcaa aaaaatttta cacattctat actataatat
     2341 attcttttta aacttaaatc aagtattccc aatattttta gttatattta cgacaattta
     2401 acctaaaata aacttcttct ttgtgttatg tacaataaaa aatagagata aaaattagga
     2461 aaataatacc aacctaactt tttctctatt catatcttat ttaaaatacg catccaatcc
     2521 atcagctata cactgcatca tttttctttg gtagtctgga tttgacatca tttggtcttc
     2581 attatagtta ctcataaatc ccatttctac taatacagct ggtacttttg accagttgaa
     2641 tccagtcaaa tcacctcttt gaacgattcc attgatttgt atacctgatt gttccatatt
     2701 ctgtttgata aattcagcac atttattact ttcttcatat ataggagctg tatattttcc
     2761 atctttttca ggaatcaata tagatgctcc agtttttgaa gaattattta aactatctgc
     2821 atgtattctt acaaccatat ctgctttttt gtcattagca agtattgctc tttctgaatt
     2881 acttatattt acatcatgtg tctctctagt cattattaca ttataacctt tagattctaa
     2941 tatactcttt aaaacaagag atgcttctaa gtttaaaaca tattctggct tttttgtagc
     3001 aataccctct gttcctgaag atactcttgc ttttttagag gaagaacctg gagctactgg
     3061 ttctaaattg ctatctcctt ttccttgatg ccctgggtct atacaaatta aaagtttttt
     3121 atttttttga atttcatttt tattatctga cgatttgtcc tctgatgact tatctttatt
     3181 acttttagaa ttagatttgt cttcattttt atctttatta tttttgtttg aattttcatc
     3241 tttatttgct ttttcatttg tgatatttcc tgaactaatc aaatttgtag tcttgtaaaa
     3301 attgctaact ggatttgatg ttcctataat tatgattccc atggcaatta tacaagtaac
     3361 taacaatcta tattttttca ttttttgctc ctttcttatg ctagacagtt attgtttatt
     3421 tttatttata tgaatatgta tttattttat catatacact atttatttta tttattttta
     3481 tgaaaactaa ggtgttattg agctagtttt ccaagcatca aaacatgatt cttgcacaac
     3541 ataatataga agcagcaaga aaacttcaat tctattatta aaataattta ataagaaaga
     3601 ggtgttttat gcaacttaaa aattttcatt ttaaaaataa tactttaagt aaaaaaacca
     3661 acttagctaa gtcaaaattt acaattgttt taacattttt atttttattt ttattatatt
     3721 ttttctcaaa taatttaatt tatgcacaaa atttacaaaa aaatgaacct gaatatttaa
     3781 taccaattgg aaacgtactt caaattgacg cagaattaaa aaatatcata gttagaaatc
     3841 ctggagaagc atctccattt agattgggtg atgctatagt aaaggtaaat aatgctgaag
     3901 ttgatggata tagtgacttt gccaatacct taaatgcttt accagaagaa aaacaagtat
     3961 ctattttatt aaatagaggt ggacaactta taacaatgaa aactaccaaa cacatattag
     4021 aaaaaattag ttttaacaat ttactttctg gatttgctac tttaacgtat atcaatccag
     4081 atacatcaga gtttggagct gtaggtcatc caataagtgt tggtaatgca agaaaaatac
     4141 ctattaaaac aggttcaatt tctacaacta agcaccttaa tatagaaaaa tcttataaag
     4201 gtagtgttgg atgtataaat gcaaaacgag aaaatattat tggtagcttt acagaaaata
     4261 ctgattttgg aataagaggt caaattaata actttgatat ttccaagtta aaaaaatata
     4321 aagtagcatc tttagatgaa gttaaattag gaaaagcaca aataatttta caagataact
     4381 ttaataagtg taaaaaatat aatattgaaa ttatagatat agaaaaccaa aaacatccag
     4441 aaagtaaaag ttttaaaatt aaaattacag ataaaaagct tttagctcaa actggtggta
     4501 ttgtacaagg tatgagtggt actccaatag ttcaagataa taaaataatc ggagcagtgt
     4561 cacatgcaat tgaaaacgac ccagctgtag gttatggtgt atttattaaa tggatgttgt
     4621 aaataatata aataaataaa taagttttaa gatgttatta agttattaat aatatatttg
     4681 gtctaaaggt acttttattt aacctacaga ccaaatatat tagatatttt acatagtata
     4741 aaatataaat ttttattaaa attatattaa tattatttcc aaaaatttta tttataaact
     4801 attattttga atttatttaa aaatatacaa ctttatatta cttgttggta ttctttccag
     4861 tgttaggtaa aacatttcct agattttttt ctggaatatt tacataactt tctggaacat
     4921 cacctactat tatagtttca caaataggta tttgagcttt aatttgtttt gttgaagtta
     4981 taagtggtat tactacttta acttgtgttt gagcttctaa atatattcta tgtctagttt
     5041 gatttatacc tgaagactca aattccgttt taaagtttac tgatactgtt cctataggtt
     5101 caatagatac ttcaagttta ggaccgtatt tagctaatat aggacttcct aatgctgttc
     5161 ctataggtat gtaagaactt gctgtcttat ccttttttaa ttcatcttgt atttctaaag
     5221 ctattgcaga tgcaatttca ttcatcatta tagtgtttgc ttgtatcata gttattttac
     5281 cattattatc aagttgtata tccattaaat cttcataatt tatttttcct tctaccatct
     5341 cagcaacagc tttatttatc gacctatttg ctagttcaag agctttagtc tctgctaaaa
     5401 ctgttattgt cggtcttaaa gttttatcta tatatataaa actgcctata aatacagaca
     5461 agaaaagaat tactaaaaaa atagctatga tttttctaaa ttcatttttt gtttttctat
     5521 ctactattct attcaaaatt atcccctcct atttatttat atgtagcttt ggcataattt
     5581 ttataatatt tgtcaaaaat aaataaaata aaaatataga ctttttaata tattacgttt
     5641 atacatatac aatgtacaga atattatagc aaattcattt tttctattaa ttacaaaact
     5701 actcctattt gtgttataat attgcattaa gtaaggaggt taaaatctta tgaataacga
     5761 taatgataaa aatggaaata aaatcaggag aaaaaaagtt agctcatctg gtaatacaaa
     5821 taaaccaatt aatagaactt cagctaacaa gactcgttca acaaaaaaca agaaaaaatc
     5881 taaaaaaagc gataaattta aaaaactaag agtatttggg atagtatttt tagttttact
     5941 agttgttggt acagcaggta ctgctggtct agtatttgcg tcactaagag atgtaactcc
     6001 agttacagaa gctgttttag ataaacagac gaaccaaaca actactatta aatacgctaa
     6061 tggaaaaaca ttatctacag ctccaagtgt aaataaaaag acacccgttc cattagataa
     6121 gatttcccct tatcttcaac atgctgtaat tgcaatagaa gatgagcgtt tttatgagca
     6181 taagggtgtc gatattaaag gtttatttag gtcagtatta aagaccctta caggtactaa
     6241 gcaaggtggt agtactattc ctatgcaggt atccaaaatg ctgttaacaa ctgaacagca
     6301 aactatacct cgtaaaataa aggatattta ctatgcacat gagatgagta aaacagtaag
     6361 taaagataaa atactagaaa cttatttaaa taacttcttc gttggtagag gtctagcagg
     6421 tgctgaggct ggtgcacgtg gttattttga taagtctgca gctgacctta ctctagcaga
     6481 gtcagcactt cttgctggtt caactaaaaa tccatcaaga ttttcagcct ataaaacttc
     6541 taagttagag ggaaatgaaa ctaaggagga tttagagaat aaattattat tttttgttaa
     6601 cacaactgat gatgatttag atgaccctac tcaagtggac tttgatatga ttgaaaaaat
     6661 aaaatcttgg gagcttatat ctaatgatac ttatagacaa ttaaaagcag gtacattagt
     6721 tgttagaaag gctgtaagta atcctgaagc taaaaaaaga caagaaattg ttttaaagaa
     6781 aatgttagaa ttgaaatata taaaacaaag tgaatatgat gaagcaatca aagctaaaat
     6841 agaaataaaa ttgcctcaat catcagataa agtttcttca tctgtagaag accttatcga
     6901 aagtgaagtt ataaatgctt taatggaaca aggacataca aatgatgaag ctcaaaactt
     6961 attctacaat ggtggtctaa ttgtaaacac aactatagac cctaaaatgc aagatgcttt
     7021 agaagaagaa tttgatagaa atagcaattt cccaggacat atggtcggtc ctgatggagt
     7081 tagccaaccg caagctgcaa tggtaatctt agattataaa aatggtgaaa taagagcact
     7141 agctggagga agaaatataa gtggtagaaa aactttaaat cgtgctacta accctcatca
     7201 gccaggttct tctataaaac ctttagcaat atatacgcca gctattgata ctctaaaaat
     7261 aacacaagca actgctctaa gtgattctcg aggaggatat aagtttaaag aaaataatga
     7321 atggaatcca agaactacta ctgctggtca tggttctatg agtttacgta aagcacttgc
     7381 taaatcttca aacacgatag ctgtcaaaac tgctgaaatg cttggagact cttatgatga
     7441 atgtgtagat ataatgatgg attacttaaa gaactttggt ataacaactt taaagaataa
     7501 tcactcaggt tcatctgaag caagtgatag aaaattccca tcattgacac taggtggtat
     7561 ggcgaatggt attactccac ttcaaatggc tgctgcttat ggtacattgg caaatcacgg
     7621 tatttatgta gaaccttcta tttttactac tataactacc tttgatggtc aattattagt
     7681 taaaaatgct cctgaagaac ataaagttgt agaccctgaa gtagcttatg ttgttacaga
     7741 tatgttagaa agcgtaatta ctgaaggtac tggtggtgtt gctacacttc caaagggaat
     7801 gcctgtagca ggtaaaacag gtactacaaa tagtgcatat gatgcttggt ttgtcggtta
     7861 cactccttat tatgttggtg caacttatat tggagatgat gctggtagaa aagatgattc
     7921 tggtaacact ataaaacgta gagaagtccc acatggaagt actagtactg caaaactatg
     7981 ggaaaaaatt atggaaaaaa tacatgctaa tttaacggtt actgaatttg aagttcctaa
     8041 aaatgtatat tttacaaaaa ttaatttaga ggatggagga aagcaatctt ctggctctaa
     8101 agcagcattt attgaaggta ctgctcctac taaagtaagt tctcaaccat catctgaaga
     8161 tacaaaaaaa ccagacaata accaaccaga agaaaataat aataacaata ataacacagg
     8221 tgataatggt ggcggttcta cacctcctga taatggcgga aacaatggtg gtggctctac
     8281 tactcctcct gataatggcg gaaataatgg tggtggctct actactcctc ctgataatgg
     8341 cggaaacaat ggtggtggct ctactactcc tcctgataat ggtggaaata atggtggtgg
     8401 ctctactact cctcctgatg gtggtggaac tccagcaact taataaaaaa tagaatttaa
     8461 ataaaaatat aaggagttgt ctcaaggtga ttaaaaaaat cactttgaaa cgctcctttt
     8521 tttataatta caatatatta tttgtattca taaaaaagag aatcccaata accagaatcc
     8581 tcctttttat ataaacaaat aaatatttta tttttaaagt ttttaactaa gtgctttatt
     8641 cttactttta ttcctaattg tttatatatt cttaaatagt tatatcacaa attatataaa
     8701 cttaatattt ttctaattac tgtataccaa atgtttgaaa tctatttaat ttgccatatc
     8761 tcttaataag catttcccac tcttctttat catagaaatc acacttattt ctaccaaata
     8821 gcttggcaac ttcaattgca aatctcccag ctgaatctaa atcactaaaa ttagttgcac
     8881 ctgtagcaca tccagcaaca ggcatctctg ttgtaattgc tactcctact attggtgcat
     8941 ctgtagctac tgctggttgt aaaatactat ttaagtgata cagattattt ccatatggtg
     9001 ttatatcttg aatagacaaa gggaatacaa atggagattt ccctgttaca gtctgcataa
     9061 tatctaaaag gttatcacta gtttttaata tgtagccttc tttaacagtt ggcgatattg
     9121 caaatcctct agtattgatt actctatttc ctttagtagt atctatagaa agtattgcat
     9181 cacaactact atcaacttca ttttcattca tagtcatcat atcaattgga gaatccataa
     9241 aaggagtagg atagtgttct ttagttggag catctgggca aatatgggtt gaaattacaa
     9301 catcaccatc taatatatcc ccttttcgtt gcatatccaa aagtttagca gccactgcaa
     9361 ttgctaccaa tgctccatca ccatctgaaa caaaacctat aacttctggt cttgctccaa
     9421 tccctcctag tctacctaaa atgccaagag taggagcatc tccacctttt aattttccat
     9481 ttttcccagg aattgtaagc tttactaaat ctgttgagcc tttacttgaa gacaattctt
     9541 ttacagttac atctacttca ccataacctt gtaagtaagt ttttacttct tccccattag
     9601 catttgcttt atctaaaatg tcataaacct ctattacttg ttttaatatc atgtctaatc
     9661 cgatttcctt tcttaatata ttttaaaatt atatattatt tactatacaa aatatctact
     9721 ccacacattg ctaacacctt aattgctttt ataagtgcta ctctgccttc ttcaccacca
     9781 gctgcaacag caaattcatc tgtatgagtt gcagtatttt cttttaattt tatatatgct
     9841 tgtattgcag gtatctcatg agttaaattt cctgtatcag ttgaacctat accttgactt
     9901 aaatctcttt caacatagtc ttcacccaaa acttcaaaat tttgtctaac tatattcact
     9961 aattcagaat cattcttaat ctctttgtat atttcatcta attgaactat ttctacatta
    10021 gttccagtag aaattgcagc tcctttagca caatttttaa gcatttcaca aatctcattt
    10081 aaatattcta tgcttaaagc tcttacatta aatatagctg tagatttttc aggaattata
    10141 ttatgtatgc tacctccatc agttataatt ccatgtactc ttgcataatc tttaagatgt
    10201 aatctcatgc tatttacact gttaaatagt gctattactc cacttaaggc acttttccct
    10261 tcccaaggaa aagcagcagc atgtgatgcc ttaccagtaa aatcaaattt taaattaact
    10321 tgagcaaatg atatatcatc aggcattgaa gcatcacttg gatgtaaaat taatgcagca
    10381 tctacattat taaatacacc ttctttaatc atagttattt ttccacctac tctttcttct
    10441 gcaggtgttc caaaaacctt tacagtccct tctatattat gttttttcat gatttctttt
    10501 aatatgatac ctgcaccaac agaacttgtc cctatgatat tgtgcccaca tgcatgtccc
    10561 attcctggaa gtgcatcata ttcagctaaa aaagcaactg ttttcccatt agttccattt
    10621 gaatacacag cttcaaaaga tgtttctaat cctcctacac ctttagttac attaaattca
    10681 ttttcttcta acaaatcaca taatgctttt tgtgacttat actcctcaaa tgctaattct
    10741 ggatttgaaa ataaatagtc agaaactttt tcaaatgatg tctttttctc ttcagataat
    10801 aactttattt cctctttaat ttttgctttt aattcattca tatttactac ctccttaaag
    10861 cattccattt aatcttaaaa ctgtttgaga tataaaagca gaaccaaagt aagtagatgt
    10921 cataactata aatgatataa ctactaactt ccaactcaaa gtctttaata tatctaattg
    10981 gttacctaca gagattcctg caaaagctaa taatggtgtt actgtagaca taaaattgat
    11041 tttccctaca tttgttgcta tgatatcccc cactggagat attggaagcg ataaaacaaa
    11101 tgcaactaat gtagcccatg caaaacctgg taaattaggt tttttaacaa aattctttat
    11161 tataatagca attatcacca acaaaaatcc agatacactt ccaatcaaca aatcttgagc
    11221 ctgagtctta agtgctatca tttgtccaaa gcaaataata atatatataa acaatactat
    11281 ttttatctgc tccataatag tcttaaaagt tttttccata tatatatcct cctttacaat
    11341 ttattacttg ttcttcttgt ttttcttcct ctaaatcttt caataactgg agctactttg
    11401 ctataatagt agttggctac tggtaaagat aagaataatt ctatatatat tccagtaaca
    11461 gctgtaatca atccactagt agctgaatat gctaaaatct gctctgacat ttgtggaacc
    11521 gtattcatta atgatgctgt tgcagctccc atcattgaac cactacccat tcctgatgcc
    11581 attgctaaag catatggatg aaatcctaaa agtacaccca ctggtgctaa aaatgaaaat
    11641 aataatgttc caaatatact accacttatg taagttccta gtgttcctat accttctggt
    11701 gagtttaatc catacttatc tccaataatt cctagtgctg tgtcacgaca taatgaaaaa
    11761 gtaccaccta atgcacttct tccaagacct aatgctactc caacaggtaa tgctatcaac
    11821 attgtaccca tatgaccaaa ttcttgtaat aaaagtgctg gtcctgcttg aagtaatata
    11881 ccaactttag gccctgcatt aattccaaac attatcccta atggatatag tgtcaaagat
    11941 aataaatatg gagatacatt tatttcatta tcccctataa acttttttaa ggctggtata
    12001 actctcccta ataaatgagg agaaacagcc attcctatga atatagccca tagtatacta
    12061 agtaaagtta cattaattcc cataacttta aatgaaatag gtccaattaa ttctgccaat
    12121 attgtgatta taaaggctgc tattatggca tttctaatcc ctgctttttc tttcatttct
    12181 atacctcctt gtaattttta taattttctt ataatataat tgttagtgat tttattatat
    12241 aacctatcat tgataatgta taatatatat ttattcatca tttttatata cttttagtta
    12301 tgaatcaaaa aaatattata gattcatgat ataaaataca aataatttat taatttatat
    12361 tgttaaaata acggattttc aaataattga ataaaattat tcattcatat tataaaaact
    12421 atctcaataa ataaaggagt acaatgtact tatatacacc tactcctttt aatttttatt
    12481 tatattattt gttaaaaaac ttcacataat ctataatatt tttaataaac gtttgatact
    12541 taaaagctta ctactttatt cttttaacgc tatttcgtat tattaacctt ggatataatt
    12601 ttctcggaat gtgttctgta ctctttttat ttattatatt tactaaacta tctactccat
    12661 tttttataac ttgctctctt gggtcatcta ttgttgataa atgcgaccta aaatatgata
    12721 ttaattcaat attattatac cctattatgg aaatatcttc tggtacattt ataccataag
    12781 tagtttttaa ctcttgtatt atagaaatcg ctggtacatc ttgttgtaca aatatagctg
    12841 aagctttttt tattttatca atgtattttt ctaaaaattc aacttgagat tcaaaatcca
    12901 ttttagattt aatgacttct gtctttaaat ttgcttcttc catagcattc aaatatccct
    12961 tggttctatc ttcatgcatt tttgaactct tatcatctga agttactgtt attatatctt
    13021 tatgaccatg gtcaattaaa tgcttggtag ctatataacc tccatacacg ttatcgtccc
    13081 aaaagaaatt atctacttct cctataaaag atggtttaaa atatataaat acatgtggaa
    13141 aattattgtc ttttaaaaaa tcatactctt ctttttttat tgattgagac acaattacta
    13201 atccgtcaac catttgtcca tttaccattt tatatacatt actatcacca ctaatgttat
    13261 tattaggctg tattataaaa tcgtatttat tagtctcaat agaatttata gaactatcca
    13321 ttatatcact aaaaaacttt ctagtatctt gatgattaaa attatttgaa aagattaccc
    13381 ctatcctgtt agtttctttt tttgctaaat ttcttgcatt tacattaaaa tggaacccta
    13441 gtctatttgc ctcttctacc actttctttt ttgttttttc agatacatta ggattattgt
    13501 ttaagcacct agaaacagtt gaataactga tacctagatt ccttgcaata tctttaatag
    13561 ttaccatctt tatcccctac ttcacttcat tttattttga taatataata ctacactatg
    13621 ttgtaaataa ttgtcaactt caattatgta aacgcttctt tatataaaaa acaggtggaa
    13681 tctaaaagat atccacctgc tttataaaaa tttattattt caaaaactta ttattctttt
    13741 aataaagatt tatggttttg cttttggagt aaatactact gacataatat atccaaagaa
    13801 tatagctgct gctattccac cagctgtagc agttgtacct cctaaaaaaa tacctaaaaa
    13861 accatcactt tgaattgatt ttattactcc tgtagcaagt gaatatccaa atcctattat
    13921 aggaactgtt gcacctgctg ctgcaaactt aactaatggc tcataaagtc ctagaaaagt
    13981 taaaactaca ccagttgtta catacgttac cataacatat ggagtttgca ttttgaaata
    14041 atccatcatt acttgggcta ttaaacatat aattccacct acaataaata ctcttacata
    14101 gtccattaac atattatatc acttcctact catttactat tactactgca tgtgcaacac
    14161 atggtattgt ctgcttttgt agtgtacttg tcggtgaaag tagtgctcct gttgatacaa
    14221 gcattacttt gttaaattct ttttttctca acttatcata tatatatcct gcaaacactg
    14281 tggctgaaca cccacatcca cttccaccac agtggacatc ttgttcttta aggttaaaca
    14341 tctctatacc acagtcagta taaacttttg atatatctac acctttttct tttagaaagt
    14401 cttctgctat ctgttttcca agagtaccta aatctccagt agcaattata tcaaagctat
    14461 ttgggtcatc attagtatct tcaaagtaag agtagatagt atctattgct gctggagcca
    14521 tagctggtcc catattatta ccatcatcaa taccctcatc tattacttta ccaacagtaa
    14581 catactttac ttttggaccg tctccattag gagctaataa tacacttcct gctcctgtaa
    14641 ctgtccactg ggctgtcatt ggtttttgat ttccaagttc aagtgggaat ctaaattgtc
    14701 tttctgctgt acaatagtga cttgatgtac ctgacagtac taaatcagca aaaccaccat
    14761 ctataagcat agaacctata caaagacctt ctgccattgt agaacaagct ccatatatac
    14821 ctaaaaatgg aatagccagt tctcttgctg caaatgatgc tggaactatt tgatttatta
    14881 aatcgccacc tagcatataa tttacatctg acaatttttt acctgccttt tggatagctt
    14941 gttgagatgc agtctctacc attttacttt cagctaattc ccaagtcttt tcaccatata
    15001 aatcgtcagt cataatcata tcaaaatagt cctttagtgg tccttcacct tccttaggac
    15061 ctactatagt tccagttgat attatggttg gtttattttc taacttgact gttctttttc
    15121 caattctttt atttttcata ttttcacacc tttttaattt tgcattttac tattcaaatt
    15181 tttaatatta attaaaaatt ttaattaaat ctgcacaatt atttttcaat tagttacttt
    15241 agtagctatt ttcagatttt ataccttctt cataattaat aaaatttaaa ttaaataaaa
    15301 atcatctaaa acatcttaaa aatataataa ataattccac ataaaataga agaacctata
    15361 ccataaacta aaactggtcc tgcaatttta aataagtttg cacctacacc taatacatag
    15421 ccttctcttt tatactccat tgctggagat actattgagt tagcaaaacc tgttattgga
    15481 attatagaac cagctccagc tctttttcct attaggtcgt aaactcctaa tccagttaaa
    15541 aatgccccta taaatattaa tgttattgat gttgcagaac tagcacctag tttatcaaga
    15601 cctccaactt tcatatacaa atcatttatt gcttgcccta tcatacaaat aattccacct
    15661 acaataaatg caagtgtata gttttttaaa tatgtaggtt ttgggcttat ttggtctaca
    15721 tattttttat aatttttatc catactaaac acctctctaa agtattattt gttaatttta
    15781 aaaaaataaa cctattattt attttgacta tctaaagttt ggtcaaaaaa taaaaaagat
    15841 gcctaataaa gaaaaaatct atttttccat aaagacacct tgtttttata tttttacttt
    15901 tttaatgctt tttattattt taatatcttt taataattta aaaacttaac ataaaaagtt
    15961 attacatttt attttagtaa tatatttatt atattttgtt attctacata tcataagtat
    16021 tatcacgata tatattcttt taacttagac aatactttct tctctatcct agatacttga
    16081 acttgtgata tattgagcat ctctcctatt tcactttgag tcatgtcttc aaagtatctg
    16141 agaactatta tttgacgctc tctcttatcc agtcttccaa gtatgtcttt taacaatatg
    16201 ttatccacta ctttttcttc ttcactttct cctttcatgc ttattttatc aataaggcat
    16261 attggagaac cttcctcttc atgaataact ccttgcaaat actcaacatt gaaattagct
    16321 tccatagcca ttactaaatc ttctttttct acatctattg ctttagctaa ttcttctata
    16381 ctcggctctc tacctaattt tttagttaaa gcttcacttt ccatctttgc ctttacagct
    16441 atttgcttta acgaccttga tacttttatc ataccatcat ctcttaagta tctctttatt
    16501 tcacctaaaa tcattggtac tgcataagta gagaatttta cattaaattt tgggtcaaat
    16561 ttatatattg attttattaa gcctatagaa cctaactgaa ataaatcttc tctatcatat
    16621 cctatattta aaaatctaga tacaacgctc ctaactagac ctaaattgct tgatattaat
    16681 atttcttttg cctcttcatc tccattttga actttttcaa taagttctag agtctcttca
    16741 tgactaagaa gaggtttttt ttcttctctg gcaacagtta cttccataat aaaacctcac
    16801 ttttggactt tatttaggca catttatttt tttagtcatt tcaattctag tcccattatc
    16861 ttttacagaa cttacctcta catcgtccat aaagcttttc attactgtga atcccattcc
    16921 tgatctatca agttctggtt ttgatgtata aagtggttcc attgccttct ccacattttc
    16981 tattccatac ccttcatctt caactataat ctttatagta tttccttcta tctcacatct
    17041 taagaaaaca aacttagaac tgtcttcttc atatccatgt attatagcat tcgtaacagc
    17101 ctcagagaca gcagttttta tatctactaa ctcatctact gttgggtcta acttagctgc
    17161 aaaggatgct actataactc ttgctaaact ttcattttca gatattgccg aaaatttaac
    17221 ttccataata ttattcatca catactcctc cctacaaaga acttagagct tcttcatacg
    17281 tatcataaat gccaataatt ttatttaacc cagataaatc aaaaatcttc ttaactcgtg
    17341 aacttatatt aattactgaa actcgtcccc cttcattaga aatcttttta tatctaccta
    17401 tgatgacgcc tatacctgaa gaatccataa aattaatatt ttcaaaatta aatacaacat
    17461 tttttacttg atttacactt aataagttat ctatttcttc ccttatttca ttggctacat
    17521 ggtggtctag ttctgagcac ataaattcta tgtatagatt cttatgttct aaggaataat
    17581 ttaccatcaa aaatccctcc ttcaatagtt ttgtaaaaat agtaactttt aatcaattct
    17641 ataattatat ttttattcct tcaatgaaat ttaactagtt ttgtcgtatt atttctacca
    17701 tactttcatt atatgttacc tgacccccaa aatctgatat accagtgtct gttaaactat
    17761 taggatttcc atgtttcttc caccaaccaa catacatttt tactatataa ttacctactc
    17821 catcatctat atttatttgt acatttattt ttgctttttt tgacctcaat atcacaatat
    17881 ctttctcctc aatacctact tttttagcca ttctctgatt tatatatgct tgagctatag
    17941 attttttgtc cataaaatgc tgactaaata aagtatctgc atgatgatta gttaataatc
    18001 taaaagaaat atttttatct tctatttctt tatatttatt gcttatatat acaggtgttg
    18061 gacttattcc caagtttttt atactttctg aataaagctc gtattttcca gatggagtct
    18121 caaacttctt atcttcccaa gcaacagggt tatgtatagt aaagtaattg tttttaagtt
    18181 tttctatatc cagatttttg tcaaaacgct taagtggttc aatcactttt tctaaataag
    18241 ttctcttttc tacaaaagga taatcattta atcccatctt tttagctagc tccataaaga
    18301 agtaatattc atccatcaat ttatgtgctg gctttacagc tctttcatta taggttatat
    18361 atggattggt cattgagcta taaattatat cttcactctc cagtgtattt gtacacggta
    18421 taaacatgtc acataaagta actgtatcag ttataaacat atcaaaacat actttaaatt
    18481 caatttttga aaacaccctc tccaattcta ctaaatctgg cagttgattc agcatattac
    18541 ttttagttat cacagccatc tttataggaa tattatcttt gattgactta ttagataaat
    18601 tatacaattc atttgatata taatctgttt tatttgatgt tatatcaagt tcatctaata
    18661 cataatttac tttatttgat gtcatatcaa gttcatctga tacataattt actttatttg
    18721 atgtcatatc aagttcatct gatacacaat ttactttatg taatgccata tcaagttcat
    18781 ctgatacacc atttacttta tgtaatgcca tatcaagttc atctgataca taatttactt
    18841 tatttgatgt tgtatcaagt tcatctgaca cataatttac tttatgtaat gccatatcaa
    18901 gttcatctga tacataattt actttatttg atgttgtatc aagttcatct gatatgtaat
    18961 ttactttatg taatgccata tcaagttcat ctgatgcata atttacttta tttgatgtat
    19021 tttttaaaga ttcttctata aatttactga tattacttac ataaaactcc ctatcttcac
    19081 catatgattg gctattgtaa gggtcagaat ttataacact cggataaact ttattagcat
    19141 agtttacccc tccaccacta aatcctattt gaccagttat agcacctaaa gcatctattg
    19201 ctcttattgt gtttccacca tttttatatt tttgaagccc atatccaaca tttatacttg
    19261 aatatttgtt agtatataaa tccactaact ctcttatatc attctcttta acaccacatt
    19321 catcaattaa aaaacttaat tccaatgaag ataaatattt tttatattct tcaaaaccaa
    19381 taacatacga gtttatatat tcttcatcat ataatttatc ttccactata atttttgcca
    19441 tagctatagc taaagctcca tctgttccag gatttacttg tacatactta tctgctattt
    19501 gagctgtttt tgtatatatg gggtcaatca ctactatctt tatccctttt tctttagctt
    19561 ttttaattat ttgcatagta tgaattgtag tatatgctgg attttttccc caaacaaata
    19621 tacttttact atttaacata tcttctatag catgactctt agctactcca aaatcatatt
    19681 tttgagcatg catccctgca ctccaacagg gaccaccctt atgtctgcta acacctccat
    19741 aaaaattaaa aaatatatct cctatgtatt ttagcacaga cccacttcca tattggtcat
    19801 aatgcatgac agactttgat gtatactttt ctttatagta tgtaagcttt tctgccatta
    19861 tttctatagc tttatcaaaa gaaatctctt tccatactcc atcaacttta agcataggag
    19921 tctttattct atctttatga tttaatctat ctaaatgggc catccctttt ttgcatataa
    19981 aaccttttgt ataaggatga tttttatctc cttcaatttt tactacatta tttcctttag
    20041 tataaacatt gaatttacaa cagtcatgac aatctaatgt acacccatga cttaattttt
    20101 ttattatatc cataaaatat ccttctttct actttcttac cttattaaaa attaacatat
    20161 atactataat ttattaaact ttctatgttc aaaactacag tatataaaac atagctatat
    20221 tttatcaaat taagtttaaa aatacttcat aaatataata ttattaaaaa attctctttt
    20281 aaaaaactaa caatcttata tgtttactta aacactatgt tttttaatta caaaaatgag
    20341 gctatctcaa aataaagata aacctctttt tcattgttta aatgctgaaa atatatttaa
    20401 ttttatacaa aaaagtgcct catgaactaa agagttcatc ttgagacact ccataaaaac
    20461 cttacataac ttgtccacca gtaatattta tagattgacc agtgcagtat tcagcttcct
    20521 ttgaagcata aaatgtaagc atatttgcaa catctataaa tctacaccct ctttttaaag
    20581 gtactttatc tatataaact tgcttgactt ctgattcagg tattcccaat tttactgcat
    20641 attgaggaat taaactttca aacatatcag aatcaagtaa attaccgagc atcagtgcat
    20701 ttacagttat cttatgttct gccaaatcta gcgctaaact ttgagtaagt cctactccag
    20761 caaatttacc tgctgaatat cctgaattat gcttgcttcc cactctacct gattttgaat
    20821 ttatctgtat tattctaccc tcaatacctt ttgctatcat gactttagat acttctcttg
    20881 caaatagaaa gtacccattt aaatttacgt ctacaataaa tttaaaatct ttgtatccaa
    20941 aatcagttat ttttttactt acagccactc ctgcattgta cactaataaa tctattctat
    21001 caaaatcatt ttcaatagct ttgacagtac ttataacctg tctttcatct atggcattac
    21061 aactatatcc tacagattta caaccaaatt cagtttttat ttcttcagct actttttttg
    21121 cgttgtcttc atttaaatct gcaatagcaa catcataacc tactttagct aaatgtttag
    21181 ataaatattc acctaaactt cttcctcctc caacgactaa agccactttt ctcattttca
    21241 tttccccttt tttatcacat taaaagttaa cttgattagt taaattgact tttatctata
    21301 atttacttat aatatgatta gattcgtttt aaattttatt ttctaattat ttttagtata
    21361 gtacctacgc caataggtgc tatttctttt tcttcaagat ataaggttcc tccaattgct
    21421 ccatcttttt cacctgtaaa cttaaatgtt atatgaccta attctgaaag attttggttt
    21481 actaactcac caacagaagt aattttgtaa tcaacattat ttattgatag cacatcatcc
    21541 gtaagtattt cttttactaa attattttca gaatgtatat aacagtaatt ttctaactct
    21601 tgaggagcat tatctttgaa agttacaaac atattatgtt gtaaaaattc atttgcatta
    21661 tctcctattt tatttatttg agtactgtat attaattcca tatcaactga acctctctct
    21721 aattatttat aaagtattct tctatttata taacccaaag cttgctaacc atgctaatag
    21781 aacagttggt gcacctgtta aaaatctaga atataaaact gacggaactc ctacttgaac
    21841 tgtatcaggt tcagcttctg caagaccaag acctactggt ataaagtcac aagctgcttg
    21901 tgagtttatt gcaaacaatg ctggtaatgc taaacttggt ggaatatttc cttttcctat
    21961 ttctgtacca accaataccc ccactatctg agctataaca gctcctggtc caagaaacgg
    22021 agacaacaac ggaaatgaac atattattga taagacaact aaacctccaa catttccgat
    22081 taatggagta agtaaattgg ctacccaatt tcctataccc gattgattta ttatacctat
    22141 taggactgca acgaaagcca taaaaggcag tatagtatgt attaatgtat ctatagtatc
    22201 cctaccagct tgaaaaagag tacttgtcac atttcctagt gctataccta tttttgcaac
    22261 aattccttga ctctgctcac ttatcttctt tttagtatca taagccatat ttcttccctc
    22321 ctactacctc aattataact gctctacatt tgttggtttt acccctgaaa catatatatc
    22381 ttcttttata aacattgcta atggtccact ttttcctgtt ttcattatat ttatagtcgg
    22441 tattttcttt tgaggatata taccacatct caatgttcca ccacaattta ttattacaca
    22501 tgcgatttca tcatctttaa caccctgtga aaatccatct attaactcac atcctgtaag
    22561 ttcagctatt tttactgcag tttctggctt tgctccccca gtcacatata ctaccttatt
    22621 cttcttttct gttggttcta ttatcaatgg tccaccccat cctccagaac cttttactat
    22681 tttaactttg ttaaatgcca tataatttat cctcctctat acactatctt tttatttgaa
    22741 aaatttattt ataccttaaa gtaattatcc aatctttata tctgaattta atgctattcc
    22801 ttgttgtttc tctacaaatt ttgttgtata gtcagtaact acacctttaa taaagtttgc
    22861 aactataccc actaacaaat atctaactgc taaatctgct gttgagaatc ccaaagttgt
    22921 tataccattt gcaattccta gatatataaa tagttcacct ggattgatat gtgggaataa
    22981 tccattcatt gtatggcatg aaaagcttgc tgctgcaaag taactaggtt taaacttttc
    23041 tggcaagaat cttcctaatg atagtgtcat tgggtttgca aatacaaatg taccaaggac
    23101 tggtaatatc aaatatctag taaatatatt tgcagaacat ttttttgcaa gtctctcgac
    23161 tctatctgta ccaataaagt tgataattgc attcattgta actaataatg ctactaaaag
    23221 tggtactata tctgttacaa aacctacaaa ttgttgccca cctgccctaa ataaattcat
    23281 aaaactatct gcaccacttg ctaatacttg aaaaaattgc gtcatattaa ctcctcctta
    23341 taaatatatt tttttaaact acttccatcc tacactcttc atcagtactc agattatttg
    23401 tatcttcaca tttatttttc tcaaatgtta tgtactgttt gactgcatct agtattgctt
    23461 ttttaagtag tttattgtaa acagttaaat ctgatttttc tatatactct aagctctttc
    23521 ctaccaaacc ttcaaatgac tttactcttg ccaatactgt aacaccttgc atttttctag
    23581 tctcgacaat cacaccatca tcatttataa gtatcaacac aattgtacct gatgaaattc
    23641 ttcctttttt tctgccaatt gccactcttc cttttctttt tagttcaata taatttttat
    23701 taaaatcttt aagctgtaag tatccaagaa aaatatttaa taaatacact gtaataagtg
    23761 atgctataat aaaaattact gggtccatat tattacctcc tcttggtaat tattttataa
    23821 aattcatcaa atgattttac cttagcaagt tcttctacca tctttttatc tctccctact
    23881 tcaagtactt cttcataact ttttattatc aggtctgtgc tatctacatt cttatctgga
    23941 attatcatca atattattat tctaatttcc tttgtatccc aaatcactgg tttttctaat
    24001 attccaaatg ccagataaag attttcccca ttagtattaa ctgagtgagg caatgctata
    24061 taattatcta atgctgttga agatttcttt tctcttttta ataccttttt tttgaactct
    24121 atatcaataa ttcctttatg aactaatttt tctaacatat cttctaaatt ttccataaac
    24181 gtactcttat tcaatataaa gaacttatcc tcttcaatta atttacctat aaaagggata
    24241 tttttttcaa tcttttttat agacttaaga tttatactat ttttcaaaag tattgcattt
    24301 tctatctctt tctttatact ttcttcatta aataacgcat ttactctaaa aattggaaca
    24361 tctaagtctg ttttgaaatc tactgttgta aatactaaat cataatactt taataaatct
    24421 aaattagctt tagcttctat atcagaaaaa gtatttactt ctacactttc tccaagtatt
    24481 tttcctatct ttattctaat aagttgtgca gtcccaagac ctgttccaca aacaacagct
    24541 accctattta catttagaac ttttcttgaa tttttttcaa aataacttcc aaaatgtaat
    24601 gctatatatc ctatttcgtg gtcacatatt ttcaagtcaa acttttcctc aattatcatt
    24661 gcagctatct ttgcaacact atatggaaat gtatatcttt cctttatttc ttgtaaaaga
    24721 ggatttttta cccttatgtt gaatctcatt ctattaagtg caaaatacaa gtgatattcc
    24781 aaattttcta taagcttttt atcttcttta aaatcaatcc ctgaggtctc taataaaaaa
    24841 ctagttactt catctacaac ttcctttacg ctatcattta tctttatact gctaagtgct
    24901 aattttgtac taggagcttt tctacctatt aatggcattg tcaaaaatat ggtttctttt
    24961 tcatttaaaa ctatattaaa tatcttttcc aataaagctt tgagctttaa tcctaaagta
    25021 tattcatctg aacatcttat cacttcaaat ctcttatcta tcttttcaaa tttgtaccca
    25081 tttagatttc ttaagacaga catgattata tatctttcaa catctctcaa gacctgttct
    25141 gttatgtaga gttcttcttt tttaaataac ttttttaatt catctctaag acattcaata
    25201 tcataatctt taactaaatt tatctgatta acgttttcca agacatcaat ataattttca
    25261 tacaatctat caaggattaa taatcttata tccatttctt caccaactaa aatcatacct
    25321 atatttggct tcctttttaa ttctaaatca tattcagcta aaattctgtc tgcttttttt
    25381 aaatccttta ttaatgttgt tcttcctata catatctctt cagccaaatc atctatggta
    25441 attggattgt tggtcatagt taaaatatca agaacataat ttattctttc atcaggtgaa
    25501 tttaaattta taaaatttga tagctttcct ctattaaaat ttacaatctc aattaattta
    25561 ctttcatcct caattcttat actatatgta cctttttcat ttttaactat tttagcaata
    25621 ccacctttta attctcgatt aatctggttt atatagtttc tgatagtcct agtactaaca
    25681 cccaaaacat ttgaaaattg ttctagagta tttgtgtctt cttctaacac catttctaaa
    25741 atcaaaaaaa ccctagggtc catataagtc attgacatct ttttctcccc tttgttatct
    25801 tacatttttt attataatct aaactatata gataattaat attctctttt tcaaatcaga
    25861 tttgaaaaaa aggaactaat atacattttt cacaacaatc tggaaaatta taacatcata
    25921 taaaacaaga aaagccttat gctgttaact cttacagatt atctactatc tgttttgaaa
    25981 acacatcagg ctttttaaat atccaatata ttattttata tattttctaa ttatagtttt
    26041 gtatactata cgttattttt tcttcttgtt tgctttttct atattaatct tattaccttt
    26101 tatcttaata tctttcatct tttcaattac tgtttttgca tcttttttag gtatttcaac
    26161 aaaagtatac ttatcatata tatctatagt acctactact ttacctggta ttccaacttc
    26221 tccagctatg gcaccaacta tatcttttgc ttgtactctt tgatttctac caatattgat
    26281 aaataatcta atcataccat ctttagctcc agtaccacct tttctatctc cacgctctct
    26341 tctaggtttt tcttctatta tttcttcttt catttcttca cctagagata gttttacaag
    26401 tgcagcagct atatcaacca ttgcataatc ttcatcatta cagaaacctt ctaaccattg
    26461 taattgttta gttaagtgac cttcttctat agtttgttta acttgtgcaa agaaagtacc
    26521 tacttttttc tcttcaacat cagttattgt tggtatatta tgctttatta gtttagattt
    26581 agtatatctt tctatatctt tcatctttct catttctttt ccaaatacaa aagtaaatga
    26641 cataccttct ctaccagcac gaccagttct accaattcta tgaacgtaat actcttcatc
    26701 ttgtggtaag tcatagttga atacacattc aacatcatca acatctatac ctctagctgc
    26761 aacatcagta gcaacaagta tatctattgt accatttcta aacttatcca ttactatatc
    26821 tctttgagtc tgttttaagt caccatgtaa tgcatctgca aaatatcctc ttgcttgtaa
    26881 atctcctacc aattcgtctg cttttctctt agtattacag aaaacaacag atagtttagg
    26941 gtcatataca tctactaatc tacataatac ttctaattta tttgatgacc tagtttctat
    27001 atagtattgc tttgtatttg aaactgtaag ttcttttcta acaactttta tatgctctgg
    27061 gtctttttga tatctcttag ttaattccaa aattcctctt ggcatagtag ctgaaaagaa
    27121 agttgtttgt ctttcttctg gaatcttact taaaatcatt tctatatctt ctctaaatcc
    27181 catatctagc atttcatctg cttcatctaa tataatcatt tttacattat ccatctttaa
    27241 tgttttacga ttgatatggt ctattgtacg tcctggtgta cctattacaa cttgcacacc
    27301 actctttaga gattttattt gtctatctat tggctgacca ccatatatag gtaatgtctt
    27361 tattccgtgc gaatacttag ctaactttct tatttctgtt gatacttgta ttgccagttc
    27421 tcttgttgga caaagcacta cagcttgtaa acttctatta tttgggtcta ttgtttctag
    27481 tatagggata ctaaaagcag ctgtttttcc cgtaccagtt tgagcttgtc ctataacgtc
    27541 tttacctgac aaaatcgcag gtatagactg tgcttgtata ggagatggtt cttcaaaccc
    27601 catttcagct atagcttttt ttattccctc acttattggt aaatcttcaa actttgttat
    27661 attcatatat tattcctctc cgttatcaat taatcttaac ctatccatta tatacttttt
    27721 taggatattc tgcaattaat attttaaaca gtatagttaa ataatataca tgaaatacaa
    27781 aattgatatg tacagaaaat atgtgaataa catcaatata ccttgtattc tactaagtct
    27841 attagattta agtgttggta ttattactat taataataat aatatcatga atggtatatc
    27901 caattgtcta ttttgagata gtattggtat gttatttggt attgctgata cagctattac
    27961 tgatactata ttcaatatgt ttgcacccaa aatatttcct actgatattt catgatgatt
    28021 ttttcttata gcagtaatcg acgaaactat ctctggcaga gaagttccaa gtgctattat
    28081 agttaaactt actatacctt gaggtatatt taaaaaacta gctattatta ctccactctc
    28141 tataaggatt tgtgaaccta ttatcatcat tatcaatcct gtagcaaaaa gtaatagtat
    28201 ttttacaatt tctaatacgg aaaaacctct ataatttttc ccttttttag tagatatgtc
    28261 tttaatagtg ttatttttaa tatttctatt tttagtatca gattttccaa cgacacttct
    28321 ataattatta accatataaa agattaatat tattataagt aataatgaat cacctcttgt
    28381 tataactcca tctaaactca ataaaattaa aactataacg gatactatta atagtaaaga
    28441 cttagaaaaa aacatttttt tatctacatt aaatggactt ataaaaacaa ccaaccctaa
    28501 tgctaatcct gtattacata ttatagaacc aactgcattt cctaaactca tagtagtatg
    28561 accatcaata gaagcaagta gagacactgt aaattcaggt aatgttgttg caaaactaac
    28621 tatagtagct ccaagtataa tttctgatat attcgttttt ttacctatct ctacagtgca
    28681 atttataaag atatctgcgc ctttagtaat taataggaaa cctactaaaa ataataccac
    28741 tgtgataaac aatctatcac ctccccctat taaataaata ttcaatttgt gaagatgtat
    28801 gctttttctt ttttccataa taaaatttat ttatcctaaa caaaaaataa aaaatatttt
    28861 ctccttaatt agctatttat ttgttttatt ttatttatat atgggtataa tttcaccaca
    28921 ttattaacat ataatctgtt ttatacttta aagcgacaat tttttatttt ttatgtatac
    28981 aggatacgaa taatatgata ttattatatt agaaaatata tttttaaaaa aatatataaa
    29041 ataaattaag tatataaaaa ttaattttaa tagtattatt tatcatttaa atctaaggag
    29101 gaaatactta atgaatgcat ggcaaggatt taaaacagga agatggacta aagaaataaa
    29161 tgttagagag tttatacaat taaactattc tccatatgag ggaaatgact ctttcttagc
    29221 tggtgctact gaaaatacta aaaaattatg ggacgaagca atggtcctat ttaaaaaaga
    29281 aagagaaaat ggtggtactt tagatgttga tacaaaaact gtttctggaa tagctgcata
    29341 tgctccagga tatttagata aagaattaga aacaatagtt gggttacaaa cggatgcccc
    29401 tttaaaaaga gctgtcatgc catatggtgg tataaagatg gttgaaaatt catgcgaagc
    29461 ttttggatat gaattagacc cagaaataaa agatatattt actaaataca gaaaaacaca
    29521 caaccaagga gtttttgatg tttatactcc agaaatgaga gctgctagaa aatctggtat
    29581 aataacaggt cttccagatg cttatggtag aggtagaata attggtgact acagaagagt
    29641 tgctctatat ggtgttgatg ctttaataga agataaaaat gagcaaaaga aatcattaga
    29701 agtttcttgc atggatgagg aagttatcag attaagagaa gaaataactg agcaaatatc
    29761 agctttaaat gaacttaaaa aaatggctga atcttatgga tttgatatat caaaaccagc
    29821 aactaactca aaagaagctg tacaatggtt atactttggt tatttaggtg ctgttaaaga
    29881 ccaaaatggt gctgcaatgt ctttaggtag aacatctact ttcttagata tatactttga
    29941 aagagattta aaagctggaa tcgtaacaga agaagaatta caagagtata tggaccattt
    30001 tgttatgaaa ttaagaatgg ttaagttcct aagaactcct gattacaata acttattctc
    30061 tggagaccca acttgggtaa ctgagtgtat aggaggtatg ggaatagatg gtagaacatt
    30121 agttactaaa aactcattta gaatgttaaa tactctatat acattagggc cttctccaga
    30181 accaaactta acagttctat ggtcaactaa attacctcaa ggattcaaag atttctgttc
    30241 taaagtatct atagatacaa gttcagtaca gtatgaaaat gatgatttaa tgagagcata
    30301 ctggggagat gactatggta tagcttgttg tgtatctgca atgagaattg gtaaacaaat
    30361 gcagttcttt ggagctagag ttaacttagc taaaacttta ttatacgcta taaatggtgg
    30421 tgtagatgag aaatctggtg ttcaagttgg accaagattt gaacctataa cttctgagta
    30481 cttagattat gatgaagtta tgagtaaatt tgaaccattc actgattggt tagcaacatt
    30541 atatgtaaat actttaaatg taatacatta tatgcatgat aaatattctt atgaagcatt
    30601 agaaatggca ttacatgata gagatatatt tagaactatg gcttgtggta tggctggatt
    30661 atcagtttgt gcagactcat tatctgctat aaaacatgct aaggttaaaa ctattagaaa
    30721 tgaacaagga atagctgttg attttgaaat agaaggagat tatccaaaat acggaaataa
    30781 tgatgataga gttgatagta tagctgtaga gttagttgaa agctttatga ataaaataag
    30841 aaagaataaa acttatagaa attcttatcc tactcaatct atacttacaa taacttcaaa
    30901 tgttgtttat ggtaagaaaa ctggtaatac accagatggt agaagagctg gtgctccatt
    30961 tgctcctggt gctaacccaa tgcatggtag agatactaat ggtgctttag cttcattatc
    31021 ttcagttgct aaattaccat atgaacatgc tcaagatggt atatctaata ctttctctat
    31081 agtacctgct gctttaggaa aagatatgac tgaaagaata aacaatcttt ctgcaatgat
    31141 ggatggatac ttcgctcaaa atgctcatca cttaaatgta aatgtatttg atagagctac
    31201 tttagaagat gctatggaac atccagaaga atatccacaa ttaactataa gagtatctgg
    31261 atatgcagtt aacttcataa aattaactaa agagcaacaa ttagatgtta taaacagaac
    31321 attccacggt aaaatggctt agtctttaaa tttttatact ttaactaaga ttactactgt
    31381 gtaaaaaata aaaataaaag gctatcttat atttgaatta tttctggtat aagatggcct
    31441 tttttagaga aatattataa ctattgataa ggttattaaa atatattgtg aggtgaactc
    31501 tatgattaag ggaaagatac attctataga aacgtttggt actgtagatg gaccaggaat
    31561 aagatatata ttattttttc aggggtgtcc tcttagatgc aaatactgtc ataacaggga
    31621 tacatgggat attaaatcag gaaaagaata cacagttgat gaaataataa cggatgctct
    31681 taagtatact tcttttatga agttttctgg tggaggtata actgcctctg gtggtgaatc
    31741 cactcttcaa ccagaatttt taagtgaatt atttaaaaaa gcaaaagaaa atgatataca
    31801 cacttgcttg gatacatctg gatttgtaga tatagaaact atagacccag ttttagataa
    31861 tactgatttg gttttacttg atttaaaaca tatggttgag gaaaaatcta ttgatttgac
    31921 tggtgttggt atggataagg cattaaaact tgctagacac ttagaatcaa gaaatattcc
    31981 tgtatggata agacatgttt tagttcctgg cattactgat gatatagata atttagaaaa
    32041 actaggtcaa tttgtagcta cattgaaaaa tgtagaaaga tttgaattgc taccatacca
    32101 ttctatggga atacacaaat gggaaagttt aggtatcgat tatgaactaa aagatgttcc
    32161 tgatgccact aaggaagatg tccaaaaagc tagtgaaata atctctaaat ttggagtgaa
    32221 agtatataat agttagtgta gtatattaat cctttataga agacataaca aaatagggta
    32281 aagtgtaaat ttttaataaa cttcaaaact tccactttgc cctattttta tatactatat
    32341 atctcatttt atatacatca ctttgatagc tgaaatttat aaaattcaga ggcacttaca
    32401 ggtcttccaa ataaaaaacc ctgaataata tctaccccta agctttttac tatatcatac
    32461 tcttcataag actctattcc ctcaacacaa acttttaaat ttataatatg agctaattta
    32521 ataatatatt caagaaaagt atattcataa ctattatatg taatattctt aacaaaactt
    32581 ctttcaattt ttattatatt aacagacagt tctttaaggt aatttaaaga tgaatatcct
    32641 gtaccaaagt catctattgc aatatatact cctataccct ttaaactaat aaatttatca
    32701 tttagtaaat ttatatctgg tatccaacaa ttctctgtta attccaaaat taaaaattca
    32761 ggtcttaatt gatactctac taaacattct actataaaat ctctaaaaaa atcttccttt
    32821 aactgaatat acgatacatt tacagatatt ttaaagtctg gatttatttt atgccattct
    32881 ttacactgtt ttacagcttc ttttataatc cacttcccaa ctggtataat taaattactc
    32941 tgttctagta ttggtataaa ttcaacagga gatacttctc cataagtact cgaatgccat
    33001 cttaaaagta cctctgcccc tattacctct tttgtaacag catttacctg gggttgaaaa
    33061 aacagctcaa agtcattaaa attattttca acgcactctc ttagtttttg ttgcattgaa
    33121 attaccttta gtttattttc atagagctct tgtgaaaaaa acttaattct atttttacca
    33181 ctaatttttg ctatatccaa tgcaatatca gcatgtttaa ataaatctaa ataattatct
    33241 ccatcttctg gatacatagc aacgcctgca gtcactgtgc aatagtactt acttgattca
    33301 atttcatgct gagtatttgt atacatctgt atcttttcat atattttctc tatagtttct
    33361 ttagtacaca tagggtaaaa aaatgcaaat tcatctccat ctaacctata caatcttaca
    33421 tcttttggaa gatattccag tacttcagta gcaattgcac gcaacacttt gtcaccataa
    33481 gaatgtccat atttttcatt tatattttta aaattatcaa tatccataat aaacatagca
    33541 ccatttttat aaattttctc ttttataaga taattcattt tatgttcaaa ttgttctcta
    33601 ttccacgttc ctgtgataga atcaaattta tttttttcac caatattctt tattctcccg
    33661 actagaaata tagtttttgg gtcatccgac acataaactt tacctctaca agaaatccat
    33721 actatttctt tatatttatt aatcaaccta tattctaaat tgtgctcacc tttttttcca
    33781 tgtagtaatt cttgtatatc atctttccat atttgaacat catctggata aacaatttta
    33841 ctccaacaat tgaccaaatc agattctatc tctttactta agttaaattc atcaaaaatt
    33901 gctgaagaaa ttttaaattt attcctattt atatcccaaa aaaatatata atcttctgta
    33961 ctttgagata aaagttcaaa gaaaatttct atatggtcta aacttaaaga gttcgattct
    34021 tctctcatct tttcccccta caatattact attagtgtag tttaatcaac aaaatatcct
    34081 tatttagatt atactatttt actaattttt tgtctcatca aacacatttc cccaacttta
    34141 gttatcttat caaatctctt actcttaact aagttttttg agattcataa agtaattttt
    34201 ctataatcat tactggtgat ttatttttac ctgctaaaac accatgttaa atcagttatt
    34261 aaatcatttt ctcttaaaat tctatttttc gttatataaa gagttatcag ttctttattc
    34321 tataaaactt ttctattact cttgaattta ttttattttt ttctccgcct attctctttg
    34381 gatttggtat tgtttttcta tagattttgg caaagaagtg tctcttccta taatataaga
    34441 ttttgatatt tcttcatcat ctataaattt tttaataggg attatatcat tttttatatt
    34501 tatttatata aatatttttt gtttttaatt ttttctatct tcttatgtac ttacatttaa
    34561 tttattcttt tcagttaata aaataggtac atttttagta catgaaaata gagttgctta
    34621 cagggtatat aggattgatg tactatttgc taatattaca ttttcaactg attcaacccc
    34681 tcttttactt acataattta agtatatttt tctggatttt taaatttatg tactttaaaa
    34741 tggatatact tattttcatt gattttgtaa gaattaataa aaaatacgat tacactacaa
    34801 aattagaatg tcaatgttta taaatataaa ataatatttt ttattttaat tattacatcc
    34861 a
//
LOCUS       DAEPHU010000041        34596 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 01A10CD0081
            SAMN05941466-rid12468953.denovo.041, whole genome shotgun sequence.
ACCESSION   DAEPHU010000041 DAEPHU010000000
VERSION     DAEPHU010000041.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941466
            Sequence Read Archive: SRR6291087
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 34596)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 34596)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068158.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 22:43:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,892
            CDSs (total)                      :: 3,805
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 87
            rRNAs                             :: 8, 1, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 55
            CDSs (without protein)            :: 55
            Pseudo Genes (ambiguous residues) :: 0 of 55
            Pseudo Genes (frameshifted)       :: 21 of 55
            Pseudo Genes (incomplete)         :: 28 of 55
            Pseudo Genes (internal stop)      :: 16 of 55
            Pseudo Genes (multiple problems)  :: 8 of 55
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..34596
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941466-rid12468953.denovo.041"
                     /strain="01A10CD0081"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            1..1008
                     /locus_tag="KR231_002116"
     CDS             1..1008
                     /locus_tag="KR231_002116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HBH0004483.1"
                     /translation="MIFTIIFYKKGRLCLLNLQSKWVNFLKPTYVSDEIKRKKLQVII
                     FFSITYGLSYSLGLLAICFNHLIDSEILAQFMMILPLSSVSIAKFYTEGRNNDKYNFY
                     SSVILFFIIYFFIFIIESLKLISINQFQLMYLMLILISSLCVIVYSYKITSLYIFKNF
                     KIGILLFFYFLFSQIIFGLIISDNQFDYKNFLNYILLPIISLVYIYPFLCEEYGWRSF
                     LQSILFDRFGKKIGIVMVGTCWSLWHLPLQFTLYSPQTPIIGAIANLIYGIGLSIFLG
                     YVYMKTKNIWFCSIMHVLINSLGLIFNDSEIIINYHSIIQRLIFILLFYTPFLFTKEY
                     K"
     gene            1388..2914
                     /locus_tag="KR231_002117"
     CDS             1388..2914
                     /locus_tag="KR231_002117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HBH0004484.1"
                     /translation="MNESYWFLNSSPKEYNKLGENIKTDCLIVGGGITGLTTAYLLAK
                     EGKKVVLVEADKIGYGTSGRNTGKVTCQHDIFYSKIEKKYGLDKAKSYYNANNEALNL
                     VEQIIEENNIKCDFKRETSFVFTEKEDTIKDIKDEYRTCKKIGINCEYHETIENIPLD
                     IKGAISFTNQGQFNPKKYIDGLAKAAVNLGLKIYENTPVVDLEKGKICRVKTREDNII
                     EAENVIISSHSPWYDGLNFYFAKEYAERAYLMVAVLENKLADGMFISIDDPSITFRQY
                     NDGSENLLIFGGGDHKVGQGGTEKEIFDDLEHYGKEVFKVKDFKGKWSAQDNMSFDNV
                     PYIGYINKREDNIYVATGFSKWGITNGTAAGIIIKDLIINNNSDYKDTFNPSRLGSYF
                     SKDFIKENANVAINYVSGKLKIGSGDMPKNNGEGKIVNIDGKRYGVYKDDNGDFYIVD
                     TTCTHLGCELNFNSEEKTWDCPCHGSRFDYKGNILEGPALKPLKLYGHGDNDVNPKLL
                     "
     gene            2942..3499
                     /locus_tag="KR231_002118"
     CDS             2942..3499
                     /locus_tag="KR231_002118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440252.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0004485.1"
                     /translation="MNKLLKPITILLYIVYILSAVFFVANKEYGSLGLVAISLVGTFI
                     LSFINKQTERLLSKELYIMLALFIMFSSLLGTCFNFYDINYYDDFLHLWSGIISCIVA
                     FSIIKYFYTQREISKMSKVFLVIFLFMFSMGVASLWEIGEFLMDTFVGTTTQAGGLED
                     TMIDMVDALIGTIITIPFIVKKSNI"
     gene            4021..5064
                     /locus_tag="KR231_002119"
     CDS             4021..5064
                     /locus_tag="KR231_002119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0004486.1"
                     /translation="MLKKWFGIVKKRQKSESAKEEGEVILKNEKILSEEKLIDEEGVV
                     VNIDNEILTKVEVVNDDNEIEEKIIEEDWLISENTIKLDDKEAIINDKNIELCKKEVQ
                     VESEKIGLNKFEGLDQNENYNLEKNVIEEKKVSECLTEEDLEYIKEIKIKRGKSIKAI
                     NLYTKEEWVFDTHIQCSKKLKVPLGYIRENLKYGYMDYFGDAINYLSEVLNIDEYCKS
                     EWSYLDNSKSPSEIFNILNNKIFSIRLSNEKRNEILTNDKIEALKMNYRFECIDEEYD
                     EYFKKYKSIIKRGGKKKVELVNKKGDILEIFKSLEECAIYLQKEKNEVIQMLKYGDTK
                     VGRNFIRYSLRSI"
     gene            5175..6317
                     /locus_tag="KR231_002120"
     CDS             5175..6317
                     /locus_tag="KR231_002120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HBH0004487.1"
                     /translation="MSEEKNPKENTLDESKNSDNVNSKKDDVSDEKNTDNKVKKREIK
                     LNNKTLKAIVAIVAVGAICLGGGYVFGKEAGRKLPATSKHYNSSEVVATIGDKKITGE
                     MLRKRMEPLFYLNAKTTMTDDEIRSYESNMIETMITSDILSSEAAKEKISITNDQLDA
                     QYNNLMSSIESAMGMTKEEFLKQFDLTEKYIKDDMKKELVASKYLNEKSKVTDKEAEN
                     YYNKNKSNYLQVRASHILIKTVDDKGKQVSSSKKAELKKEAEEILKKAQAGEDFATLA
                     KKYSEDSSAESGGDLGFFGKGQMVESFEKAAFALKKGEVSNKLVESDYGYHIIKKTDE
                     KYQPFEEVKSDLVSSLTSEKQNLLIQNLKEKYNVKITDKYQMKAKE"
     gene            6771..8162
                     /locus_tag="KR231_002121"
     CDS             6771..8162
                     /locus_tag="KR231_002121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide MFS transporter"
                     /protein_id="HBH0004488.1"
                     /translation="MSSTESVSKKSGHPKSFWLICMTILWERFSYYGLTALLVLFFTA
                     SVAQGGLGLSTQEATSMFGLFTGLIYLTPLVGGWLADKVLGQQKCISIGALLIAIGDF
                     VLFASSTSIAMVWVGLSIIILGNGFFKSSCSNIVGDIYPKTDVSRKDAAYSLFYMAVN
                     VGAFIAPIICGLLSDNVFAVRGASGDIVSYGYKMAFLICGIGMMLGMIIFTLLAPKLL
                     NEVGKYPVTKGNKGEKIEYGPLTKLEKNRIIAMVILFLFVVLFWTAYYQTQSSFMIYV
                     RDNVNRTLFGFEMPVAWLTSLNAILCVALCPVLATLWVKLSHTKRGDFSIPVKMGLGM
                     IIMGVGFIVMVFATLANGPDGMVKASILFIVLTYIFTTVGELFLSPIGLAMFNKLAPA
                     KYATLSMGAWYLTSFFASLLSGKIAGFTATLGFLQIFGGIATVLIIFGLILLGIRNVL
                     TRLMAMDLLTKEK"
     gene            8415..10208
                     /locus_tag="KR231_002122"
     CDS             8415..10208
                     /locus_tag="KR231_002122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HBH0004489.1"
                     /translation="MNIKDRLSGLRKFMEEKNIDAYMIPSSDNHQSEYVGDYFKSREF
                     ISGFNGSAGTVIVTKDEAGLWTDGRYFIQAESQLEGSTIKLFKMGQEGCPTTDEYLYK
                     NIPEGGTLGFDGRVISAREGATLAEKLSKKGIKIEYQYDLIDSIWPDRPALSDSKAFL
                     LDVKYCGESFSSKLARLREKMSEKGTSTHVITTLDDIAWLFNIRGGDVKYNPVVLSYA
                     VITLKEVYLFVDESKLNEEILNELAKENVQIKPYNDVYEFVKNIDKTEKVLLDGTKLS
                     YTIYNNIPCEVEKVDEFNPVMFFKAQKNEVELENIRNSHVKDGVAFTKFMYWLKKNVG
                     KMEITEISATQKLEDLRREQEGFFEPSFNTIAAYKEHAAMMHYSATPESNYKLEAEGL
                     FLVDSGGQYYDGTTDITRTTVLGPISDELKLHFTSVARGMINLSKAKFLHGCRGYNLD
                     ILSRSCMWNMGIDYQCGTGHGIGFVLNVHEAPNGFRWRVVPERFDSAVLEEGMVTTNE
                     PGIYIEGSHGIRTENEIVVRKAEKNFYGQFMEFEVVTLAPIDLDGIVPELMNKDEKDY
                     LNWYHKLVYDKISPFLTDEEREWLKVYTRAI"
     gene            complement(10289..11671)
                     /locus_tag="KR231_002123"
     CDS             complement(10289..11671)
                     /locus_tag="KR231_002123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide MFS transporter"
                     /protein_id="HBH0004490.1"
                     /translation="MSVLKTQEKLKQPRDLYFCCSIFTFVGLAYYGMKLVLLLFLAEQ
                     VSKGGLGLTPAESASMLASFLAWTYFSPVIGGWVSDRFLGPKNCIILGMLMVSIGYFL
                     GYIANSKMDINIMIFLSGLGIGFYKGNLHTMVGNLYTNDDPRKDGAFSITYMATNLGT
                     LFGPLICGLVANEWFAMKSGLSISMYGYRYVFLFSSITVLIGLFFFIFGNRKFYKPLN
                     NDPSNGRESIRKSLEYKKMLASRPLTLIEKKRIIVILVLAFFTVFFWIAYNQASMSIA
                     LYTKEHINLTVGNFQIPTSWIDSYNGLLCVILGPISALVWVKLSQTKKGDLSVPKKMS
                     LGFILLAIAFLFMIVAVIQTGTDPNSIHKASVFWVVGFLTFQSIGEICFSPVGYGMVN
                     KLSPEKYISFLMGVWFLGKFAANKLSGYTQAIIDQLGMLQVFIVIPSFLLIFGIILLI
                     MNKKLVELSN"
     gene            11929..12276
                     /locus_tag="KR231_002124"
     CDS             11929..12276
                     /locus_tag="KR231_002124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupin domain-containing protein"
                     /protein_id="HBH0004491.1"
                     /translation="MIRKKSELQVEVKENLNGGIGKVKLENIIQNEELKGKGRLFKRV
                     ALPVGSSIGVHDHTTDFEVYYILKGKGKVFDNGEFVEVNEGDVVYTADGEKHSIENIG
                     EEDLEFVALVLYM"
     gene            12294..13328
                     /locus_tag="KR231_002125"
     CDS             12294..13328
                     /locus_tag="KR231_002125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0004492.1"
                     /translation="MTGKIEEIKDKINRFCNSNLNQEYKDISFKILQNLLDNNKEIIH
                     SSRADIWSSAILNIVLEQNLLYNKKHPLHITKKEFSKQIGVSLNTINNKSSLIKDVCS
                     IDFLNQDTIAISNVEFWVKETNSKSKSVDLDLEKKKILYKRYIKLSQDANSDIESIRY
                     MEEAVNIGKSMITKEDKELGFWKGLSTRAYMIALESLARKLESINNLKESKKVLEYLI
                     EINPSDEQGIRYKLLNVLIRLNDRTSINKLFELYKEEKSATWMYSKALYYFKNKSMFL
                     ANDSIKVARSKNKYVGLYLLDWRNAFGREFVTEEEKAEAVYYYDENIVIWNEVKGSMD
                     WLLKKMLEFS"
     gene            complement(13377..14426)
                     /locus_tag="KR231_002126"
     CDS             complement(13377..14426)
                     /locus_tag="KR231_002126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBH0004493.1"
                     /translation="MEINYKKRNFKSFAKRKNIEISVQRYLIDALSYMALGLFSSLLI
                     GTIFNTLGDNFNISLFTEVISPLAKQVTGPAIAVAIAYGLQAPPLVLFSCALVGACGN
                     ELGGPVGAFVATLFAVEVGKLVSKETKIDILVTPAVTILIGVLVAELIGPAVSAFMTS
                     FGNIIMQATTMQPIIMGALVSALVGIALTLPISSAAICMMLSLGGLAGGAATVGCCCQ
                     MVGFAVMSFRENGVGGLVAQGLGTSMLQVPNIIKNWKIWIPPTVASILLGPLSTTIFK
                     MENIPIGSGMGTCGLVGQFGTVTAMQSAGKGGISMWVGILLLNFILPAIVTLLISEFM
                     RKKGLIKPEDLKLDV"
     gene            14701..16236
                     /locus_tag="KR231_002127"
     CDS             14701..16236
                     /locus_tag="KR231_002127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0004494.1"
                     /translation="MIFVKNKKYRKIAIIISIPILLVAQYYLFKFGILRPMVKGVEIE
                     IVDGEYVKDIDKYVVKLNETVTLSTGEYIKVPSYAKNPNIWFNVLDNSGTLKIDGNKM
                     TALKVGYSSVGIMKNSRVLKKATIKVVDPEVESLDMEINGDLKHVGDSATIESTIEVD
                     YDKFKKSYKPVYKSSNENILKIKGNKVSAVGVGKATIYAKCGNKEIERTFRIQARVAE
                     INMDDIKIEVDQNEKLKPDIITSPPGLEPPKIYYELVDSKLPVERAISLSSNGNVVGL
                     REGKDRVRITCGDKSKVITVTVVKETITNDYIQNLVGSHKIVNNKVIIKLEWDYMKDV
                     FDYDIYLKDKLSGESFKKIKSITINESDLGKSNKVYATIEVDMKGNQNIDFDIYVIGK
                     KDSDTTKPSNVINITNGNGNSNNDNNIKDMRVENISANVDRDNNVIRVNWSSISHKDC
                     TYSIYVKNNTNGDGEFTLYQSDIQGNEHTISIPEGDLNLDIYVVANYNGNSSQNSDVI
                     NVR"
     gene            complement(16421..17107)
                     /locus_tag="KR231_002128"
     CDS             complement(16421..17107)
                     /locus_tag="KR231_002128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate/glutamate racemase family protein"
                     /protein_id="HBH0004495.1"
                     /translation="MKTIGLIGGMSWESTITYYQVINTVIKERLGGLHSSKCILYSVD
                     FQEIEECQSSGNWEKSAKILADAAIKLQEAGADFIVICTNTMHKVSDKIQESIHIPLL
                     HIADVTATVLREKEIKKVALLGTKYTMEQDFYKNVIINNGIEVLIPNEEDRIIVNDTI
                     FNELCLGIISESSKKAFLSIIDKLGKQGAEAVILGCTEIGLLIKQNDTSIPLFDTTVI
                     HAIEAALSSI"
     gene            17232..18614
                     /locus_tag="KR231_002129"
     CDS             17232..18614
                     /locus_tag="KR231_002129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HBH0004496.1"
                     /translation="MPINSFENYPMTWKPKLDNRKPPIYKTLAMLLEEDIKRGNLNPG
                     DKLPPQRELADFLDLNLSTITRAFKLCEEKGLICAKVGKGTFISSDVNVSNTLLYQTE
                     SKDIIELGTVHPPYEQNTYIIDFIKNVLKQPEMDRFLQYMSPSGTYMQKKSIAKWIER
                     NNVYTSEENILLSTGGQNAICATLLGLFKAGDRIATDSLSFSGIKSIAKMIGIQLVPI
                     PQENNEISIEYLESYCKNENIKGIYLIPDYHNPTTHTMSDLSRKKIAKIAKQYNIIII
                     EDAINSIFRDGIQTPIFSLASDNTIYIFSTSKFLCAGLRVAFVVAPKRYIENLENALY
                     NMNLMVSPFTAEIVHRLLYSPIIDKIIEEKRDAIIERNEVADKVLSDYNLIGDKNCSF
                     RWLLLPDELDGKSFEISAKNLGVQVYCAERFSVGNSTVPKAVRICVTAPKDVEELEKG
                     LNIIKSLLKS"
     gene            19016..20284
                     /gene="eam"
                     /locus_tag="KR231_002130"
     CDS             19016..20284
                     /gene="eam"
                     /locus_tag="KR231_002130"
                     /EC_number="5.4.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate 2,3-aminomutase"
                     /protein_id="HBH0004497.1"
                     /translation="MNEQTRISLERAAELKSKIDDYIQARKTINRGLEKEEEINKRKQ
                     KILSILNGTEEDWNNYKWQLSNRITDVDTLSKIITLTKKEKEYIKEVGTQFRWAISPY
                     YLSLIDPEDICDPIKLLSIPTHIELEDEQEDLDPMGEEYTNPAGCITRRYPDRLIINV
                     TNECAMYCRHCQRRRNIGQQDSHKSKAIIQESIDYIRENEEIRDVLVTGGDALTLKDD
                     YLEWILSQLKEIPHVDYVRLGTRTLVTMPQRITDEFCNMLKKYHPVYINTHFNHPMEI
                     TKESKEACEKLANAGVPLGNQAVLLNGINNDKFVMRCLNQELLKIRVKPYYIFQSKHV
                     KGTKHFNTSVDDGLEIMEYLRGYTSGMAIPTYIVNAPKGGGKTPLLPQYLVSKGTDYV
                     MLRTWEGKVIKMEDEPAVDIKKLIKEQAQD"
     gene            complement(20377..20733)
                     /locus_tag="KR231_002131"
     CDS             complement(20377..20733)
                     /locus_tag="KR231_002131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0004498.1"
                     /translation="MKKALISLLVLSCLLLTAPVNESSYADSQKNVPVSQNTKLTQEQ
                     AKELLVKYNNEVDYIYQGNASDFEALKAKNLNGYVFLPDADGDIGYFVNENTSEIYYF
                     HPSGYLELVNQQQNNK"
     gene            complement(20884..21978)
                     /locus_tag="KR231_002132"
     CDS             complement(20884..21978)
                     /locus_tag="KR231_002132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HBH0004499.1"
                     /translation="MQDKKIYLNIVLTVVVSYILIKVIDNYKYFFGVISLLMSLLTPF
                     IIAFVLAYIFNPLVKFLESKLNFKRIYSLLLTYGVLIVILISFILFTVPSIVNSLADL
                     VAQIPTYIDKTEQFLFDLGKSLQSVDPNTLKEYGDKIMSVMPKFSNLLIGSLGGIFST
                     TFSVGKFIVQFLLGFIICFYILLEKEKFLLFTKKVVYISLGKKYGDFIIELCQSLNLN
                     IGKYFTGKILDSFIVGVLSGIGLYFLKSEYALLFGTLMGVMNMVPYFGPVIGMAPVVI
                     INLFSNPTIALTSLIYLIIIQQVEVTFIEPKIVGGQLGLSPFFTILAVTVGGGFFGIP
                     GMILSAPVMGVIKIYFCEFVNRRHDKIQME"
     gene            22442..23263
                     /locus_tag="KR231_002133"
     CDS             22442..23263
                     /locus_tag="KR231_002133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MoxR family ATPase"
                     /protein_id="HBH0004500.1"
                     /translation="MIKKEISNFRGSSDYVVSPELMASVNVAIALEKPLLIKGEPGTG
                     KTMLAQAISNELKKDLVIWNIKSTTKAQEGLYVYDTVQRLYDSQFGGEGVDDISKYIK
                     YGKLGEAFSSNQQVILLIDEIDKADLEFPNDLLWELDKMEFYINETKETVRAKQRPIV
                     IITSNAEKELPDAFLRRCIFHYIEFPDRDMMEEIVKVHFDKVEEHLLEQVMTTFYWIR
                     SLKDIQKKPSTSELIDWIQALTLSGMPIEKIEKEVPFAGILLKNNEDIESMQRHL"
     gene            23284..24480
                     /locus_tag="KR231_002134"
     CDS             23284..24480
                     /locus_tag="KR231_002134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VWA domain-containing protein"
                     /protein_id="HBH0004501.1"
                     /translation="MFIEFFYLLRSRGLNVSLNEWMTLIEALDKGLCYSNFSNFYYLC
                     RMILIKSESDFDKFDAVFLEYFKGIEHQEEIPEEIMNWLKKPDIDLEEFERLEQNPNI
                     NLDKLRAKLEERIKEQDSPHNGGNYWIGTGGTSELGHSGKGQTGIRIGGNSTYGRAVL
                     EVAGERKYRDFRDDEVLNMRQFQVALKRLRQFSTRIDAPKTELDLDKTIEETCNNAGY
                     LKLFFEKPRKNTVKLLLLMDSGGSMRGYSTLCNTLFQSVSKSNHFKDVKIYYFHNCIY
                     DRLFTTPECWLSKSINTEWILKNIDKNYKVIIVGDASMSPSELLHIGGNYRGPYNYTP
                     GIEWLKRFKRKYSKIVWMNPELRDGWDSINYWYQTQRMIQSEFNMFPLTVKGLEKALK
                     NLMVSR"
     gene            24647..28045
                     /locus_tag="KR231_002135"
     CDS             24647..28045
                     /locus_tag="KR231_002135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S8 family serine peptidase"
                     /protein_id="HBH0004502.1"
                     /translation="MIIINYELIVKYNGDILRLEEELGVSVEILNSSYAIITSSNEED
                     VNILLTYPEIEFIEKPFILQTQDVQSFSSTGITGFKNRTGLTGKGTIIGIIDSGIDYT
                     LPVFRDSDGRSKILYYWDQSIQGNPPEGFREGTLYTNEDINNAIDGSMYIPISTTSLH
                     GTHVAGICATIASDARIIVVRVGNIQTDIFSRSTEFMRAIKFILDRALELRMPVTLNI
                     SYGSNEGSHRGTSLFEQYIDDMCLFWKNNIVVAAGNNADKGGHKRIRLQNNITEEVEF
                     IVGEGERILNINIWPDFVDDFSVHLVNPSNNQTQAISLTSGEIRNTLGETRITGYFYP
                     IAPYSLTRRVTLQLSSNTQITPGLWKIVFEPIDIVTGNVNIYLPTSEGLNRNTRFLIP
                     TQELTVTVPGTASRVITVGSFNSRTDIVSIFSGEGDTQLGVFKPDLLAPGEDIVSFLP
                     GGTSGALTGTSMATPHVTGVCSLFMEWGIVNGNDLFLYSQKLRALLLKGARRLSNQSY
                     PNNSSGFGFLNLSDIDLYTLSNINQDLETEDIGYRSINKSFKDEENSYKFIDGYNMQI
                     HNDLENEIYISKNASRQSGILSGIDIVHTPEFEEELAGLGMSQRFFKISDSLGVLSIN
                     NTDYNSIQRVLQLPSIIRTVSTTKMTLLGEINRGTFGGVVATEEMGVNFFKNNPNINI
                     TGRGTLISIADTGIDYLHPDFIYPDGTSKIVYLWDQTKEGTPPDGFYIGTEYTREDIN
                     RAIAENDPSLSQDEVGQGTMLSGICAGLGNVNSEYAGIAEDSELIIIKLGKIDDFYNS
                     AMLFAASQYAYKKAFELGRPLVINMSLGTSSLAGLTNRSNSEKAFFTRGLCITAGAGN
                     EGNTQTHTSGIIPYVGGSVEVELELNEDEEELSLELWLNRPDKADVIIVSPTGEESKS
                     VGISNYNKVTGLFDLEGTEYSITYIYPTTFSGQQFTNVTLKNAKRGVWKIRLVGVYII
                     TGRYNLYLPNRELLKSGTRFREVDPFYTINYPAIQDDLITIGAYNTINGSLWQSSSRG
                     PTIEDRLKPDIVAPGVNIIAAYPGNTYATITGTAAASAHAAGAAAMYFQYTFVDGRYP
                     NQAYVQKIKTFMQAGARKDSNTVYPNTNSGYGLLDVRGMFDVLR"
     gene            28055..29728
                     /locus_tag="KR231_002136"
     CDS             28055..29728
                     /locus_tag="KR231_002136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S8 family peptidase"
                     /protein_id="HBH0004503.1"
                     /translation="MEKSYCIIYQGDIESALQENGINRYMVLNSQLAVIYVPLDFDET
                     ILNNIIQVAWWEESEPMSSLIEITNNVNNGETITTAAETDYIYENPYNDITGRGILLA
                     VIDSGIDYLHPDFINDDGTSKVLYLWDQEANTNPPPEGFIFGSEFTRSELNIAINRND
                     GSLSQDNIGTGTLVSGILVGNGRINSQYRGITTESDLIVVKLKSYTDTYYAGRINYSV
                     SDFLAAITYVTNIARTENKPLIINLTIGVKSSAVATTSILDTFNILSSAGVVVVSGAG
                     NQGNTDIHYSGRFSSVGEVQDVIIQDGDDYALDITLNTNGPDKVGAQIISPSGEVSHD
                     IRYSPDFYIYRGKFNLENTTYAMRFIYPYITSGKENLEIRLRDIKPGVWILRLTSELI
                     INGEYDIYLPNKNLIAPDTRFLDPDSVATITMYAASDDVITVGTFNNKTDSMWIGSSK
                     GPIRGRGIKPDIVASGVDIISTYKNGTYNTGTGTGVSSSIVTGVLALLMEYLEKQDNV
                     PRLSLFTQVLKTYLILGATKLEIYTYPNVSQGYGILNLKNTIQQIANTL"
     gene            30001..30195
                     /locus_tag="KR231_002137"
     CDS             30001..30195
                     /locus_tag="KR231_002137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3787 domain-containing protein"
                     /protein_id="HBH0004504.1"
                     /translation="MESKKARALKGKDNKRLKSSLLVGNESTAAWADVEKLKPHSKVS
                     IPSIKGVEEAKDWVDNGSKL"
     misc_binding    30364..30597
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            30674..32071
                     /gene="asnS"
                     /locus_tag="KR231_002138"
     CDS             30674..32071
                     /gene="asnS"
                     /locus_tag="KR231_002138"
                     /EC_number="6.1.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine--tRNA ligase"
                     /protein_id="HBH0004505.1"
                     /translation="MQKEFITVKELYREKEQYIGKTVKVAGWIRTSRVSKNFGFIELN
                     DGSFFKNMQIVFDEKVENFKEVGKLAISSSILVEGELVSTEGAKQPVEIHAKSIVVEG
                     ESDSSYPLQKKRHTLEYLRTIAHLRPRSNTFSAVFRVRSIAAYAIHKFFQERNFVYAH
                     SPIITGSDCEGAGEMFRITTMDLNDIPKTEDGKIDYTQDFFGKEANLTVSGQLNAEIM
                     ALSFRNVYTFGPTFRAENSYTGRHASEFWMIEPEIVFADLEDNMELAEDMIKYVISYV
                     LENAPEEMEFFNSFIDKGLLERLNKIVNSEFIRITYTKAVELLIESGHEFEYPVEWGC
                     DLQTEHERYITEQIYNCPVFVTDYPKDIKAFYMRMNEDGKTVRAMDLLVPGVGEIVGG
                     SQREEREDVLLDRINEMGLREEDYWWYLELRKFGTATHSGFGLGFERIIMYMTGMSNI
                     RDVIPFPRTPKNAEF"
     gene            complement(32244..33419)
                     /locus_tag="KR231_002139"
     CDS             complement(32244..33419)
                     /locus_tag="KR231_002139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GGDEF domain-containing protein"
                     /protein_id="HBH0004506.1"
                     /translation="MNLEKIKKFFGFPLDKKHKDNVEKELCNYLYHTGKIICIIIVIS
                     QIIMMISISAREGGPFVTPRRQWYFYMYVTLFCVSSVFMFVFSYLWNKKKDCCTFYIN
                     LWIIYVTFFCLWGCVITLLDQLGGNDLSVFSYIMLAAAAFSVLKFGESVIVFGGCFLF
                     LNLFLPGIQTIPGNEFSNIVNTFFITSLAIFVSTMLYRNRVFTYYDKLLISQQYEEIS
                     HINNLLNDKVMTDDLTKMNNRRYLEDILQKKLISHANQEPITGMMIDIDYFKQFNDNY
                     GHQKGDYCLQNIAKVILDFTSSENEHAIRYGGEEFFICIFNCNEADAKLKSECLRKII
                     ESCNFERDDVPLKCVTVSIGVYTKKIGKTITLNEFISNCDKALYTAKEQGRNCVAFY"
     gene            33838..>34596
                     /locus_tag="KR231_002140"
     CDS             33838..>34596
                     /locus_tag="KR231_002140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0004507.1"
                     /translation="MGEKKINNMNYSHNNYSKKTGEPTRKIKNSHITLKSKEEKICSS
                     CNKENNTKDNYCKFCGNELYEIASLRPLETKLDLKSKIKELSYHANKRGVFLTTFTTI
                     FILFIIALIFKAIITIQFNDISYLVNPAHIILALNLGQISVSMSTMMGSGFINANIGL
                     LILLIIPILVLLISNLIFMRKRCRDSKTVLANSLGVGIFYGLVLAILSIFTNVKTSSH
                     SMLEYGYALEYSYEFFSVLLNGFVLGFICTYITTY"
BASE COUNT        13553 a         3887 c         5794 g        11362 t
ORIGIN      
        1 atgattttta caattatttt ttataaaaaa gggaggttat gtttgttgaa tttacaatca
       61 aaatgggtaa actttttaaa gccaacatat gtcagtgatg aaataaaaag aaaaaaacta
      121 caagttataa tatttttttc tataacttat ggtttatctt attcactagg tttattagca
      181 atatgtttta atcatttaat agattcagaa attttagctc aatttatgat gatattgcca
      241 ttatcttcag tttctattgc aaaattttac acagagggaa gaaataatga taaatataat
      301 ttctattcat cagtaatatt attttttatt atttactttt ttatatttat tattgaatca
      361 ttaaagttaa taagtattaa tcaatttcaa ttaatgtatc ttatgttaat tttaataagt
      421 agtttatgtg ttattgttta ttcttataaa ataacaagtt tatatatttt taaaaatttt
      481 aagataggta ttttgctatt tttttacttt ttgttttctc aaattatttt tggattaata
      541 ataagtgata atcaatttga ttataagaat ttcttgaatt atattcttct tcctataata
      601 tcattagtat acatttatcc ttttttatgt gaagagtatg gttggagatc ttttttgcaa
      661 agtattttat ttgatagatt tggcaaaaaa atagggattg taatggtagg cacttgttgg
      721 agtttatggc acttaccttt acaatttaca ctatatagtc ctcaaactcc aataattgga
      781 gctatagcca atttgatata tggtattgga ctttctatat ttttaggtta tgtttatatg
      841 aaaactaaga acatatggtt ttgctctata atgcatgttc taattaatag cttaggatta
      901 atttttaatg attctgaaat aattattaat taccatagta ttatacaaag attgatattt
      961 atactattat tttatactcc ttttctattt acaaaagaat ataagtaaga attacaatta
     1021 atttatataa aataaatttt taagtaaata tttttataga gagattgtta tattacatat
     1081 cagaaaaata ttaaactaac taaatcaata aaaaagttgg tggataacaa tttataattg
     1141 ttagcacaac atcatcttat gtattgaaat ctaaaatatc ctcattttta cttagcataa
     1201 atactattaa ttaagaaaat aatatagaaa ttataaatat atataagttt agtctggtgt
     1261 ataaaacaag aaaactaagt gatttttaat ttaacttttt attaagctta ttttttatac
     1321 tatttataat aaataaactc catgatggga aaactattac tatttaatat gtaaaggagt
     1381 attttaaatg aatgaatcat attggttttt aaactcaagt ccaaaagaat ataacaaatt
     1441 aggtgaaaat ataaaaacag attgtcttat agtaggtggt ggaataactg gattgacaac
     1501 tgcatattta ttagcaaaag aaggtaaaaa agtagtgctt gttgaggctg ataaaatagg
     1561 atatggaact tctggaagga atactggtaa ggtaacttgt cagcatgata tattttactc
     1621 taagatagag aaaaaatatg gattagataa agcaaaatca tattataatg caaataatga
     1681 agctttaaat ttagttgaac aaataataga agaaaacaat ataaaatgtg attttaaaag
     1741 ggaaacttct tttgtattta cagaaaaaga ggatactata aaggatatta aagatgaata
     1801 tcgtacatgt aaaaaaatag gaataaattg tgagtatcat gaaactatag aaaatattcc
     1861 attagatata aagggggcta ttagttttac taatcaaggt caatttaacc caaagaagta
     1921 tattgatgga ttggcaaaag cagcagtaaa tttagggcta aaaatatatg aaaatacacc
     1981 agtagtagac cttgaaaaag gaaaaatatg tagggttaaa acaagagagg ataatataat
     2041 agaagctgag aatgttataa tttcatctca tagtccatgg tatgatggat tgaattttta
     2101 ttttgcaaaa gaatatgcag agcgtgctta tttaatggtt gcagttttgg aaaataaatt
     2161 agcagatggt atgtttataa gtatagatga cccatcaata acttttagac aatataatga
     2221 tggaagtgaa aatttactga tttttggagg aggagaccat aaagttggtc agggaggaac
     2281 tgagaaagaa atatttgatg atttagagca ttatggtaaa gaagtcttta aggtaaaaga
     2341 ttttaagggg aaatggtctg ctcaagacaa tatgagtttt gacaatgttc cttatattgg
     2401 ttatatcaac aaaagagaag acaatattta tgtagctaca gggttctcta aatggggaat
     2461 tactaatgga actgctgctg gaataataat aaaagatttg ataataaata ataattctga
     2521 ttataaagat acttttaatc catccagatt aggtagctac ttttcaaaag attttataaa
     2581 ggaaaatgca aacgtagcaa taaattatgt aagtggaaaa ttaaaaatag gtagtggaga
     2641 tatgcctaaa aataatggag aaggaaagat tgttaatatt gatggaaaaa gatatggtgt
     2701 atataaggat gataatggag atttttatat tgtagacact acatgtactc atttaggatg
     2761 tgaacttaat ttcaacagtg aagaaaaaac atgggactgt ccatgtcatg gttctagatt
     2821 tgactataag ggaaatatac ttgaaggacc agctcttaag ccattaaaac tttatggaca
     2881 tggtgataat gatgttaatc ctaagttatt ataaaattat ttttaggaag gtaaagtgta
     2941 tatgaataaa cttttaaagc caataactat actattgtat atagtttata ttttatctgc
     3001 cgtatttttt gtagcaaaca aagaatatgg aagtctaggt ctggtagcaa ttagtttagt
     3061 tggtactttc attttgagtt ttataaataa gcaaacggaa agattattga gtaaagaatt
     3121 atatataatg cttgctttat ttataatgtt ttcatcattg ttaggtactt gttttaattt
     3181 ttatgatata aattattatg atgatttttt gcatttatgg tcaggtataa tatcttgtat
     3241 tgtggctttt tctataatta aatactttta tacacaaaga gagataagta aaatgagtaa
     3301 agtgttttta gttatatttt tatttatgtt tagtatggga gtagcgagtt tatgggaaat
     3361 aggtgaattt ttaatggata cttttgttgg gactactaca caggccggag ggttagaaga
     3421 tactatgatt gatatggtag atgctttaat aggcacaatt ataactattc cttttatagt
     3481 aaaaaaatct aatatatagt tttaaatttt ttatattaat tataatggat ttaattaatc
     3541 atgttgagtt tcaaggtcta tatgattaat taaatccatt tttgttattt ataattatta
     3601 ttgaatatat ttttacatat aagatataag gtgatagata gaaattgttg gattatgtaa
     3661 ataattaata tataatacca ttatgggcaa taaatacaaa tcaaatgata atatagtcta
     3721 tttatgtaaa tgttatattg tatactaagt ataatagtaa gttttttgat agtggtgtag
     3781 aaagtaaaaa tctactagcc taaattgatg tatggattag tttaggaaca gtaattgcat
     3841 atcttaagtt tgatgtcatg ttgggctact agaaataggt catctttttc acttgaatat
     3901 cttttcttta aacatggaga gtatcatatc aaaaacatat gaaaattaag tgatttataa
     3961 gaacagtaat attttatatg atagtataga atagtaataa agtattagga ggaacattga
     4021 gtgttaaaaa agtggtttgg tattgtgaaa aaaagacaaa aaagtgagtc agcaaaagaa
     4081 gaaggtgaag taatattaaa aaacgaaaaa atattatctg aagaaaagtt gatagatgaa
     4141 gaaggagttg tagttaatat tgataatgaa atattaacta aagtagaagt agtaaatgat
     4201 gataatgaaa tagaagaaaa aataatagaa gaagattggt taattagtga aaataccata
     4261 aaattagatg ataaagaagc aattattaat gataaaaaca tagaattatg taaaaaagaa
     4321 gttcaagttg aaagtgaaaa aataggttta aataagtttg aaggacttga ccaaaatgaa
     4381 aattataatc tagaaaaaaa tgttattgaa gaaaaaaaag taagtgaatg tttgacagaa
     4441 gaagatttag agtacataaa agaaattaaa ataaaaagag gaaaaagtat aaaagctata
     4501 aacttgtata ctaaagaaga gtgggttttt gacactcata tacagtgtag taaaaaactc
     4561 aaagttccat tagggtacat aagagaaaat ttaaaatatg gatatatgga ttactttgga
     4621 gatgcaataa attatttaag tgaagtatta aatatagatg aatactgcaa aagtgaatgg
     4681 agctatctcg ataatagcaa atctccatct gagatattta atattctaaa caataaaata
     4741 tttagtataa ggctttctaa tgaaaaaaga aatgaaattt tgacaaatga taaaattgaa
     4801 gcattaaaaa tgaattatag atttgaatgt attgatgaag aatatgatga atattttaaa
     4861 aaatataagt ctataatcaa aagaggtgga aagaaaaaag ttgaattagt aaataaaaaa
     4921 ggtgacattt tagaaatatt taagtcttta gaagaatgtg ccatttattt gcaaaaggaa
     4981 aagaatgaag ttatacaaat gttaaaatat ggagatacaa aagtaggaag aaactttata
     5041 aggtatagtt tgagaagtat ttaatttcat tttaaattca taagagtttc atttctgatt
     5101 cacacattta atattatttt aatgtaaaat aataaaggtg aagtattgca caattaaaat
     5161 taaggagggt attaatgtct gaagaaaaaa atccaaaaga aaatacatta gatgaatcta
     5221 aaaattcaga taatgtaaat tctaaaaaag atgatgtgtc agatgaaaaa aatactgata
     5281 acaaagttaa aaaaagggaa ataaagctaa acaacaaaac acttaaagct attgtagcaa
     5341 ttgttgcagt aggagctata tgtttaggtg gaggctatgt ttttggcaaa gaagctggaa
     5401 gaaaattgcc tgctacttca aaacactata atagcagtga ggtagtagct actattgggg
     5461 ataaaaaaat aacaggtgaa atgttaagaa agagaatgga gccattattt tatttaaatg
     5521 caaaaactac tatgactgat gacgaaatac gttcatatga atcaaatatg attgaaacta
     5581 tgattacatc tgatatatta tcctctgaag cagcaaaaga gaaaataagt ataactaatg
     5641 accaactaga tgctcagtat aataatttaa tgagtagtat agaatcagca atgggaatga
     5701 ctaaagaaga gtttttaaaa cagtttgatt tgactgaaaa atatataaaa gatgatatga
     5761 aaaaagagct agtagcatca aaatatttaa atgaaaaatc aaaagttact gataaagaag
     5821 cagagaacta ttacaataaa aacaagagca attatttaca agttagagct tcacatattt
     5881 taataaaaac tgttgatgat aaaggtaagc aagttagtag tagcaaaaaa gctgaactta
     5941 agaaagaagc tgaagaaata cttaaaaaag cccaagctgg ggaagatttt gctactctag
     6001 ctaaaaaata ctctgaagat agtagtgcag aatcaggtgg agatttaggt ttctttggta
     6061 aaggtcagat ggtggaatct tttgaaaaag cagcctttgc attgaagaag ggagaggtat
     6121 ctaacaaact tgtagaaagt gattatggat atcatataat taagaaaact gatgaaaaat
     6181 atcagccatt tgaagaggta aaatcagatt tagtaagcag tttaacatca gaaaaacaaa
     6241 acctacttat acaaaatcta aaagaaaaat ataatgttaa aattacagat aaatatcaaa
     6301 tgaaagctaa agaatagata aagtcaattt attaaaaaaa agaaaaatta actgtatgga
     6361 taaaagctat ttttactctt aatatagaga gtataaaata gcttttatta ttttgcaata
     6421 aaatctattt atatatatga agtgacaaag aaataacatg caaaaagata ttaaaaagaa
     6481 atatttttaa tttgaatttt ttcaataaaa atttacaaaa atgaaaaaac aaacaaaaaa
     6541 gaattgaaga tttaagttgt tatttaaata tatatatatt aagattttct gctgaagata
     6601 ctaaaaaaat aatatttttc ataattttaa aaataataat aaaaaaatga aaatacaggc
     6661 gataatctat tgagtaaaca tagaaaagat gatattataa gtatgtgcta aaatggttaa
     6721 agcaatatta atattaaatt taactataaa acaaaagggg gcgttttttt atgtcaagta
     6781 cagaaagcgt atctaaaaaa agtggtcatc cgaagagttt ttggcttatt tgcatgacaa
     6841 ttttgtggga aagatttagt tattatggtt taacagcttt attggtatta ttttttacag
     6901 caagtgtagc tcaaggtggt ttaggtcttt ctactcaaga agcaacatcc atgtttggct
     6961 tatttacagg tcttatatat cttacaccat tagtcggtgg ctggttagca gataaagttt
     7021 taggtcaaca aaaatgtatt tctataggtg cacttttaat agcaatagga gatttcgtac
     7081 tatttgcttc atctacatct attgcaatgg tttgggtagg tctatcaata attattttag
     7141 gaaatggttt ttttaaatca agttgctcaa atatagttgg ggatatatat cctaaaactg
     7201 atgtgtcaag aaaagatgca gcatacagtt tattctatat ggcagtaaat gtaggagcat
     7261 ttatagctcc aataatatgt ggattgcttt ctgataatgt atttgcagta agaggagcaa
     7321 gtggagatat agtatcttat ggatataaga tggcattttt aatttgtggt ataggcatga
     7381 tgttaggtat gattatattt acacttcttg caccaaaatt attaaatgaa gtcggaaaat
     7441 atcctgtgac taaaggtaat aaaggtgaaa aaattgagta tggaccactt actaagttgg
     7501 agaaaaatag gataatagca atggttattt tatttttatt tgtggtctta ttctggacag
     7561 catactatca aacacaaagt tcttttatga tttatgtaag ggataatgta aatagaactc
     7621 tatttggatt tgaaatgcca gtagcatggc ttacatcact aaatgctata ttatgtgtgg
     7681 ctttatgccc agtattagct accctatggg ttaaattatc tcataccaaa agaggtgatt
     7741 tctctattcc agttaaaatg ggattaggaa tgataataat gggtgttggg tttatagtta
     7801 tggtatttgc tacattagct aatggtccag atggaatggt aaaggctagt atattgttta
     7861 tagtattgac ttatatattt acaacagtag gtgaattatt cttatctcct ataggacttg
     7921 caatgttcaa taaattagct ccagctaagt atgctacgtt gtctatggga gcctggtatc
     7981 taacaagttt ttttgcaagt ttattatcag gaaagattgc tggttttaca gccacacttg
     8041 gttttttaca gatatttgga ggaatagcaa cagttttaat aatatttggt ttaatattat
     8101 tgggaataag aaatgtatta acaagattaa tggctatgga tttactaaca aaagaaaaat
     8161 aattcatgac gaattattgt aaataaatga attactttaa ataaaggaag ttacatttaa
     8221 atataaaatt aaatgtaatt tcctctttga ttatgaaaaa aagctttaca caaatagata
     8281 ttataattaa aattataatt gtgataatta gagtgtataa gatttatata aattatacaa
     8341 aaaatattta tgtaataaac tttacatact tatatattta gttattcaaa ctattatttc
     8401 gaggaggtct tgttgtgaat ataaaagata gattaagtgg attaagaaaa tttatggaag
     8461 aaaaaaatat agatgcctat atgattccat cttctgataa tcaccaaagt gaatatgtag
     8521 gagattactt caaatcaaga gaatttatat cagggtttaa tggttcagca gggacggtta
     8581 ttgtgactaa agacgaagct gggttatgga cagatggaag atattttata caggcagaat
     8641 ctcaattaga aggaagtaca ataaaattat tcaaaatggg acaagaaggt tgcccaacta
     8701 cagatgaata tttatataaa aatattcctg aaggaggaac tttaggattt gatggtagag
     8761 ttatatctgc tagagaagga gctacattag ctgaaaaatt atctaaaaaa ggtataaaga
     8821 tagaatatca gtatgattta atagatagta tatggccaga tagacctgct ttatcagata
     8881 gtaaagcatt tttattagat gttaaatatt gtggagaaag ttttagctca aaattagcta
     8941 gattaagaga aaaaatgagt gaaaaaggta cttctactca tgtaataact actcttgatg
     9001 atatagcatg gttattcaat ataagaggtg gagatgttaa atataatcca gttgtacttt
     9061 cttatgcagt aataacttta aaagaagttt atctatttgt tgatgaaagt aagttaaatg
     9121 aagaaatact aaatgaacta gctaaggaaa atgttcaaat aaagccatat aatgatgtgt
     9181 atgaatttgt aaaaaatata gacaaaactg aaaaagtttt attagatgga actaagctta
     9241 gttatacaat ttacaataat ataccttgtg aagttgagaa agttgatgag ttcaatccag
     9301 taatgttttt taaagctcaa aaaaatgagg tagaattaga aaatataaga aattcacatg
     9361 taaaagatgg tgtagctttc actaaattta tgtactggtt aaagaaaaat gtaggtaaga
     9421 tggaaatcac tgaaataagt gctactcaaa aattagagga cttaagaaga gagcaagaag
     9481 gtttctttga gccaagtttc aatacaattg ctgcatataa agagcatgct gcaatgatgc
     9541 actatagtgc aactccagag tcaaattata aattagaggc agaaggatta tttttagtag
     9601 attcaggtgg acaatattat gatggaacta ctgatataac taggactaca gttttaggac
     9661 ctataagtga tgaattaaaa ctacacttta cttctgtagc aagaggaatg ataaatcttt
     9721 ctaaggctaa gttcttgcat ggttgtagag gatataactt agacatacta tctagaagtt
     9781 gcatgtggaa tatgggaatt gattatcaat gtggaactgg acatggtata ggatttgtgc
     9841 taaatgttca cgaagctcca aatggattta gatggagagt agtacctgaa agatttgata
     9901 gtgcagttct tgaagaagga atggtaacta ctaatgaacc aggtatatat atagaaggtt
     9961 ctcatggtat aagaacagag aatgaaattg tagttagaaa agctgaaaag aatttctatg
    10021 gtcaatttat ggaatttgaa gttgttacgt tagctcctat tgacttagat ggtatagtac
    10081 cagaattaat gaataaggat gaaaaagatt atttaaactg gtatcataag ttagtttatg
    10141 ataaaatatc acctttctta actgatgaag aaagagaatg gttaaaagtt tacactagag
    10201 ctatatagtt tgtactagat acaataaaaa tcgaggtatt ataatgcctc gattttttat
    10261 tgtatatttt attaacttta aaaaattttt aatttgataa ttctactaat tttttattca
    10321 ttataagtag tataattcca aatatcaata aaaatgatgg tatcactatg aagacttgta
    10381 acataccaag ttggtctata atagcttgcg tatagccaga taatttattt gctgcaaatt
    10441 tgcctaaaaa ccaaacaccc attaggaatg aaatatactt ttcaggcgaa agtttattta
    10501 ccataccata cccgactgga gaaaagcaaa tttctcctat actttggaat gttaaaaatc
    10561 caactaccca aaatacactt gctttgtgaa ttgaattagg gtctgttcct gtttgtataa
    10621 ctgctactat cataaacaaa aatgctatgg ctaatagtat aaaacctaag ctcatttttt
    10681 ttggcacact taaatcgcct tttttagttt gagataattt tacccatact aaagcagaga
    10741 taggtccaag aataacacaa aggagaccat tgtatgaatc tatccatgaa gtaggaattt
    10801 gaaaattgcc aacagtaaga tttatgtgtt cctttgtata gagtgcaata gacatagagg
    10861 cttggttata tgctatccaa aaaaatactg tgaaaaaagc taacaccaat attactatta
    10921 ttcttttttt ctcaatcaaa gttaaaggtc ttgaagctag cattttctta tattctagtg
    10981 attttcttat agactctctc ccgttactag ggtcattatt caaaggttta taaaactttc
    11041 tgtttccaaa tataaagaag aataaaccta ttagaaccgt aattgatgaa aataaaaata
    11101 catatctata tccatacata cttatagata atccgctttt catagcaaac cattcattag
    11161 caactaaacc gcatattaaa gggccaaata aggtacctag attagtagcc atatacgtaa
    11221 tagagaaagc tccatctttt cttgggtcat cattggtata taagtttcca accatagtat
    11281 gtaagtttcc tttataaaaa cctattccta atccagataa aaatatcatg atgtttatat
    11341 ccatcttact atttgctatg tatcctagaa aataaccaat tgaaaccatt agcattccaa
    11401 gtataataca gtttttggga cctaaaaatc tatcactgac ccatccacca ataactggag
    11461 agaaataagt ccatgctaaa aaagatgcaa gcattgatgc ggattctgct ggtgttaacc
    11521 ctaaaccacc tttggagact tgttcagcta aaaacaataa taataccaat ttcataccat
    11581 agtatgcaag tcctacaaag gtaaatattg aacagcagaa atataaatct ctaggttgtt
    11641 taagtttttc ttgcgttttt aaaactgaca tatgtcgaga acctccagat aaatagttta
    11701 acaaaatttt accatactat atgagtatat gtttttttca tatagacgtc aacttgtaag
    11761 ataatttaat taagtcgaaa tatatgtaaa aatagtatca tttttgtgta ttcagtaata
    11821 tttttttatg ataatatatg ttattattat attaaaatac aaacatattt atggaaagga
    11881 tatgccaatt tagtagttag attgattgtt tggcaggtgg gatgagctat gataagaaag
    11941 aaatctgaat tacaagtaga agtaaaagaa aatttaaatg gtggtatagg aaaggttaag
    12001 cttgaaaaca taatacaaaa tgaagagctt aaaggaaaag gaagactatt taaaagagta
    12061 gctttaccag taggaagttc aattggtgtg catgaccata caacagattt tgaagtatat
    12121 tatatactaa agggaaaagg taaagtattt gataatgggg aatttgtaga agtaaatgag
    12181 ggtgatgtag tgtatacagc tgatggcgaa aaacattcta tagaaaatat aggagaagaa
    12241 gatcttgagt ttgtagcact agttttatat atgtaaaata tggaggagga gtcatgacag
    12301 gcaagataga agaaattaag gacaagataa atagattttg caactccaat ttaaatcaag
    12361 aatacaaaga tataagcttt aaaattttgc aaaacctttt agataataat aaagagataa
    12421 ttcattcttc tagagctgat atatggtctt cagctatact aaatatagtt ttagaacaaa
    12481 atcttttata caataagaag catccactac atataacaaa aaaagagttt tcaaaacaaa
    12541 taggtgtttc tttaaatact ataaataata aatcgtcttt aataaaagat gtttgtagta
    12601 ttgacttttt aaatcaagat actatagcta tttctaatgt agaattttgg gtaaaagaga
    12661 ccaattccaa atcaaagtct gtagatttag atttagaaaa gaaaaaaata ctatataaaa
    12721 gatatattaa gctatcacaa gatgcgaata gtgatattga atcaattaga tatatggagg
    12781 aagctgtaaa tataggtaaa agtatgatta ctaaagaaga taaagaactt ggattttgga
    12841 aaggtttatc taccagagcc tatatgatag cacttgaatc ccttgctaga aagttagaaa
    12901 gtattaataa tctaaaggag tccaaaaaag tattagaata tttaatagaa attaatccta
    12961 gtgatgagca gggaataaga tacaaattat taaatgtatt aattagatta aatgatagaa
    13021 cttcaataaa taaattattt gaactttata aagaagaaaa atctgctaca tggatgtaca
    13081 gtaaagctct ttattacttt aaaaataaaa gtatgttttt ggcaaatgat tctattaagg
    13141 ttgctagaag taaaaataag tacgttggat tatatttgtt agattggcga aatgcttttg
    13201 gtagagaatt tgttacagag gaagaaaagg cagaagctgt ctattactat gatgaaaaca
    13261 tagtgatttg gaatgaagtt aaaggttcta tggattggct attaaaaaaa atgttggaat
    13321 tttcataaaa aaaactactc cttactttta tataagtaaa aggagtagtt tttaatttat
    13381 acatctagtt ttaaatcttc aggttttatt agaccttttt ttctcataaa ttctgaaatc
    13441 aacaaagtta caatagcagg aagtataaaa ttaagtaaaa gtataccaac ccacatagat
    13501 atacctcctt ttccagcact ttgcatagca gttactgttc caaattgtcc aaccaatcca
    13561 caagtaccca taccagaacc aataggaata ttctccattt tgaatattgt tgtagataat
    13621 ggtccaagta atattgaagc tacagtaggt ggtatccaaa ttttccaatt ttttattata
    13681 ttaggtactt gcaacataga tgtcccaaga ccttgtgcca caaggccgcc aactccattt
    13741 tctctaaagc tcataacagc aaagcctacc atttggcaac aacaacctac agttgctgca
    13801 ccaccagcaa gaccacctaa acttaacatc atacaaatag ctgcactact tataggtaat
    13861 gtaagagcta ttccaacaag tgcagagact aaagctccca ttattatagg ttgcatagtt
    13921 gtagcttgca ttattatatt tccaaatgaa gtcataaaag cagaaacagc tggaccaata
    13981 agttcagcta caagtactcc aattagtatt gttacagcag gtgtaaccaa tatatctatt
    14041 tttgtttctt ttgaaactaa ttttccaacc tctacagcaa aaagtgtagc gacaaatgct
    14101 ccaacaggtc ctcctaattc attaccacaa gctccaacaa gtgcacaaga aaatagtaca
    14161 agtggaggtg cttgaagtcc atacgcaata gccactgcta tagctggacc agtaacctgt
    14221 ttagcaagag ggcttataac ttcagtaaaa agagaaatat tgaaattatc tcctaatgta
    14281 ttgaaaattg ttccaattaa aagggacgaa aaaagaccga gtgccatata acttagtgcg
    14341 tcaataagat acctttgaac agaaatttca atattttttc ttttagcaaa tgatttgaaa
    14401 tttctttttt tataattgat ttccaattta aaatcctcct catataatat aagtataatt
    14461 tctttttaat taattatata acttttcagc tgacaagaca aatgttattt cactaaaatt
    14521 agactattgt aatagtaaga aattaacatt aattttagtt ttaaatttta aatttatggt
    14581 ttataattag tatagggata ttctgaaata taataatttt ccagtttatc ccaatattta
    14641 acttaggtag attgcttaca aaacaaatga ttatatatta ggctaaaagg aagtggatag
    14701 atgatatttg taaaaaataa gaaatacaga aaaattgcca taattatatc tattcctata
    14761 ttgcttgttg cgcagtacta cctttttaaa tttggaatac ttagaccaat ggtaaaggga
    14821 gtagaaattg aaattgtaga tggggaatat gttaaagata tagataaata tgtagtaaaa
    14881 ttaaatgaaa cagttacttt gtctacaggt gaatatatta aggttccttc gtatgctaaa
    14941 aatccaaata tttggtttaa tgtattggat aactcaggga ctttaaaaat agatggaaat
    15001 aaaatgacag cattaaaggt tgggtattct tctgtgggta tcatgaaaaa ttcaagagta
    15061 ttaaaaaagg ctactataaa agtagtagac ccagaggtag aatcactaga tatggagatt
    15121 aatggggatt taaaacatgt tggtgatagt gctactatag aaagtacaat agaagttgat
    15181 tatgataagt ttaaaaaatc atataagcca gtttataaga gtagcaatga aaatatttta
    15241 aaaatcaaag gaaataaagt aagtgcagtt ggagttggta aagctacaat atatgctaag
    15301 tgtggaaata aagaaattga gagaacattt aggattcaag ctagagttgc tgaaataaat
    15361 atggatgata taaaaataga agttgaccag aatgaaaaat tgaaaccaga tataataact
    15421 tctccacctg gtttagaacc accaaaaata tattatgagt tagtagattc aaaattacct
    15481 gtagaaagag caataagttt aagtagtaat ggaaatgttg tagggcttag agaaggtaaa
    15541 gatagggtga gaataacttg tggagataaa tctaaagtaa taacagtaac agtagtcaaa
    15601 gaaactataa cgaatgacta tatacaaaac ttggttggtt cacataaaat agtaaacaat
    15661 aaagttatta ttaaacttga atgggattat atgaaagatg tctttgatta tgatatatat
    15721 cttaaagata agttgtcagg agaatcattt aagaaaatta aatctataac tataaatgaa
    15781 agtgatttag gtaagtctaa caaggtatat gcaactatag aagtagatat gaagggtaat
    15841 caaaatatag attttgatat ttatgtcata ggtaaaaagg attcagatac aactaagcca
    15901 agtaatgtaa taaatattac caatggaaat ggaaattcaa ataatgataa taatattaaa
    15961 gatatgaggg tagaaaatat atcagctaat gttgatagag ataataatgt cattagagtt
    16021 aactggagta gtatatctca taaggactgt acttacagta tatatgtaaa aaataatact
    16081 aatggagatg gagaatttac tctatatcaa agtgatatac agggaaatga gcatactata
    16141 agtattcctg aaggagattt aaatctagat atttatgttg ttgcaaatta taatggaaat
    16201 agctctcaaa atagtgatgt tataaatgta agatagattt gtatacaaat tgaaagtgtt
    16261 gagtttattt aaatattaaa ttaagaaaaa ggatagtata gggtaattat actatccttt
    16321 tttgttacaa tatataggtt taaaatctct agtaatataa attataaaaa gtcttattta
    16381 cacaaatcta tagatatttt ttttattaat caatattgtc ttaaattgaa cttagtgcgg
    16441 cttctattgc atgtattact gtcgtatcaa atagtggaat agaagtgtca ttttgtttaa
    16501 ttaaaagacc tatttctgta catcctaata taacagcctc tgcaccttgt ttgccaagct
    16561 tatctataat agataagaaa gctttttttg aagattcaga tataattcct aagcaaagtt
    16621 cattaaatat tgtgtcattt actattatac ggtcttcttc atttggaatt aagacttcaa
    16681 ttccattatt aataattaca tttttataaa aatcttgttc cattgtatat ttagtaccta
    16741 ataaggccac tttttttatt tctttttccc ttaataccgt agcagttaca tctgctatgt
    16801 gaagtaatgg aatatgtata ctttcttgta ttttatctga taccttatgc atagtattag
    16861 tacagataac aataaaatct gcccctgcct cttgtaattt aattgcagca tcagctaaaa
    16921 ttttggcgct tttttcccaa tttccactag attggcattc ttcaatttct tgaaaatcta
    16981 cactgtaaag tatacattta gaagagtgta gtccacctaa tctttctttt attactgtat
    17041 taataacttg ataatatgta atggtacttt cccaactcat accaccaatt aagcctatag
    17101 tcttcatatt atacctctct tatttattta ttttgaaata gctatttaca aatacaagta
    17161 tagcatctaa aatagaagca tacaataata aaattgtatg gagtacaatt ataattaaga
    17221 ggagtaatta tatgccaata aattcttttg aaaactatcc tatgacatgg aaaccaaagt
    17281 tagataaccg aaaaccacca atatataaaa ctttagcaat gttattagaa gaagatatta
    17341 aaagaggaaa tttaaatcct ggagataaat tgcctccaca acgggaatta gcagattttc
    17401 tagatttaaa cttaagtaca ataacacgag catttaaact ttgcgaagaa aagggactaa
    17461 tatgtgcaaa agtgggaaag ggaacattca tttcttctga tgtaaatgta agtaatacat
    17521 tattatatca aacggaatca aaagacataa ttgagttggg gacagttcat cctccgtatg
    17581 agcaaaatac atatattatt gactttatta aaaatgtact aaaacaacca gaaatggata
    17641 ggtttttaca atacatgtct ccatctggca catatatgca aaaaaagtca attgcaaaat
    17701 ggatagaaag aaataatgta tacaccagtg aagaaaatat attattatct acaggagggc
    17761 aaaatgctat atgtgcaact ttactaggat tatttaaagc tggtgataga attgctacag
    17821 attctttaag tttttctgga attaagtcaa tagctaaaat gataggtatt caattagtcc
    17881 caattcctca agaaaataat gaaatatcga ttgaatatct tgaaagttat tgtaaaaatg
    17941 aaaatataaa aggcatatat cttataccag attatcataa tccaacgaca catactatgt
    18001 ctgatttatc tcgtaaaaag atagccaaga tagcaaagca atataatata ataattattg
    18061 aagatgctat aaatagcatt tttagagatg gtatacaaac tcccatattt tctttagcta
    18121 gtgataatac tatatatatt tttagtacat ctaaattttt atgtgctggt cttagagtag
    18181 catttgtagt tgctccaaaa cgatatatag aaaatttaga aaatgcacta tataatatga
    18241 atctaatggt ttctccattt acagcagaaa tagtacaccg tttattatat tctcctatta
    18301 tagataaaat tatagaagag aaaagagatg caattataga aagaaatgaa gttgctgata
    18361 aagttttgtc agattataat ttgattggtg ataagaattg cagttttcgt tggttacttc
    18421 ttcctgatga attggatgga aaatcatttg aaatttctgc aaaaaatcta ggagttcaag
    18481 tatattgtgc cgaacgattt tcagtaggaa actctacagt tccaaaagca gttcgtattt
    18541 gtgtaacagc tccaaaagat gtagaagaat tagaaaaagg gcttaatata ataaagtcac
    18601 ttcttaagag ttaaatttat tttactatta tttaattaaa taaataaaaa ggcggagaaa
    18661 tttattataa taaacctccg cttttattat ttaatgaaat actttacttt ttattaaaaa
    18721 atttaatttt aataatcttg aaaatataat cgttttatgg taaaataatt cttaaaaata
    18781 gaaaaaatta atcatttgtt aaaaaaaatg cataatttat tgtaatttat tgacgaaggt
    18841 tgaaaaatat tcataaatgt gcgaaataac agaaaaaatg caaaaattaa ttcaatttca
    18901 tttgttataa aatctatatg gcaaaattaa atctgcctat cagaatgata taaacacatc
    18961 agaaaggagg acgctatcaa ataatacaag tagttaactt tgatagcaaa aaattatgaa
    19021 tgaacaaact agaatatcct tagagagagc tgctgaatta aaatcaaaaa ttgatgatta
    19081 tattcaggct agaaaaacga ttaacagagg tcttgaaaaa gaagaagaga taaataaacg
    19141 aaaacagaaa atattaagta tcttaaatgg aactgaagag gattggaata actacaaatg
    19201 gcaattatca aatagaataa cagatgtaga tactttatca aaaattataa ctctaactaa
    19261 aaaagaaaaa gaatatataa aagaggttgg tactcaattt agatgggcaa tatctccata
    19321 ttatttgagt cttatagacc cagaagatat atgtgaccca ataaaattac tgtctatacc
    19381 aacacatata gagttggaag atgagcaaga agatttggac ccaatgggag aagagtatac
    19441 aaacccagca ggatgtataa ctagaagata cccggataga ttaataataa atgtaacaaa
    19501 tgagtgtgct atgtattgta gacactgtca gagaagaaga aatattggac aacaagattc
    19561 tcataagtca aaagctatta tccaagaatc tatagactat atcagagaaa atgaagaaat
    19621 aagagatgta ctagtaactg gtggagatgc tcttacatta aaagatgatt atttagagtg
    19681 gattcttagc caacttaaag agataccaca tgttgattat gttagattag gtactaggac
    19741 tcttgttaca atgccacaaa gaattacaga tgaattttgc aatatgctaa aaaaatatca
    19801 ccctgtatat ataaatactc attttaatca tccaatggaa ataactaagg aatctaaaga
    19861 agcttgtgaa aagttagcaa atgcaggcgt tccattagga aatcaggcag tattattaaa
    19921 tggaataaat aatgataaat ttgtaatgag atgtttaaat caagaattac tgaaaataag
    19981 agtaaaacct tattatatat tccaaagtaa acatgtaaag ggaacaaaac atttcaatac
    20041 atcagtagat gatggtcttg aaatcatgga gtatttaaga ggatatacat caggaatggc
    20101 tataccaaca tatatagtaa atgctccaaa aggaggagga aagactcctt tgcttcctca
    20161 ataccttgta tcaaaaggaa cagattacgt tatgcttaga acatgggaag gaaaagttat
    20221 aaaaatggaa gatgaacctg ctgtagatat aaagaaactt ataaaagaac aagcacagga
    20281 ttaaaaaaat atttaaagtt tataaaaaga aacaacttta aaataaaaag aaaatggatg
    20341 tcaaatttat atcaatttgc atccattttt tattagttat ttattatttt gttgttgatt
    20401 aactaattca agatatccac ttgggtggaa gtaatatatc tcagaagtat tttcatttac
    20461 aaagtaacca atatcaccat ctgcatctgg taaaaataca taaccattaa gatttttagc
    20521 ttttaatgct tcaaaatcac tagcatttcc ttgatatatg taatcaactt cattgttgta
    20581 ttttactaaa agttctttag cttgttcttg agtcaattta gtattttggc ttacaggaac
    20641 attcttttga gaatctgcat aagaagattc atttactggt gcagttaata acaaacaaga
    20701 taaaactaat aaagatataa gtgctttttt catactaaaa ccctctttca tgtttaatta
    20761 tataagattc attacttaat aatattgtat gtttcctata attaaatatt accattaaag
    20821 agaataatat tacagttaca cagctgtaac ttttgattac aaaatcgtaa ttaaattgta
    20881 tttttattcc atttgtattt tatcatgtct acgatttaca aactcacaga agtatatctt
    20941 tataacgccc atcacaggag cagatagaat cataccaggt ataccaaaga atcctccacc
    21001 aacagtaact gctaggattg taaagaatgg gctaagacct agttgtccac ctacgatttt
    21061 tggctctata aatgtaactt caacttgttg aattattatt aagtaaatta aagaagttaa
    21121 agcaattgtt ggattggaga ataaattaat tattacaact ggtgccatac ctattactgg
    21181 accaaaatat ggaaccatat tcatgacacc cataagtgta ccaaataata gtgcatattc
    21241 agattttaaa aagtaaagac caattccaga aagtactcca actataaaag aatctaaaat
    21301 cttacctgta aagtatttac caatatttaa atttaagctt tgacatagtt ctattataaa
    21361 gtctccatat tttttaccta aggaaatata aactactttt tttgtaaaca gtaagaattt
    21421 ttctttttct aataatatat agaaacaaat tataaaacct aaaagaaatt gtactataaa
    21481 ttttccaact gaaaatgtag tgctaaatat cccaccaagt gaaccaataa gcaagttact
    21541 aaatttaggc attacactca taattttgtc accatactct tttaatgtat tagggtcaac
    21601 tgattgtaaa ctcttgccta agtcgaataa aaactgctct gttttatcta tgtatgtagg
    21661 aatttgagca actaaatcag ctaaactatt tactatggat ggaactgtaa ataatataaa
    21721 cgaaattagt ataactatga gtacaccata agtaagaagt aacgaatata ttctcttaaa
    21781 atttaattta ctttctaaga actttactag tgggttgaat atatatgcta atacaaatgc
    21841 tattataaat ggtgttagta gtgacattaa taaacttatc actccaaaaa aatatttgta
    21901 attatcaata actttaatca agatatatga aacaactaca gtgagtacaa tatttagata
    21961 aattttttta tcttgcaaaa taacacaacc tttcttatat ttattaaatt tagatatact
    22021 taaatctaag ttaaagttaa tatttatagc ttattataca ataaaaagca gtattaatat
    22081 agtatgatta atatgaaatt ataaatacgt taaaacttta tgtttatagc taaaataata
    22141 aaaattattt atattgtgtt tatatataat ctaaaatgaa aaaaagtggt gcctttgatt
    22201 aaactaagtt tttataattt aaattttgta caataagcta tcttttatta ttctttaaaa
    22261 tatatatttc atttaattat gacaaataaa gataaaaatt aaatatttta gaggtgattt
    22321 tatttagata tagaatttta gaataatact atacaaatgt attgtattat tatttttata
    22381 tcaaaaatag taataaagtc tatatacatt tagaaaatac tgtttaaaag gagtaggatt
    22441 tatgataaaa aaagagatat ctaactttag aggaagtagt gattatgtag tatcaccaga
    22501 attgatggca tcagttaatg ttgctattgc tcttgaaaag ccacttttga ttaagggcga
    22561 acctggaaca ggtaaaacta tgctagcaca agcaatttca aatgaattaa aaaaagattt
    22621 agtaatttgg aatataaaat caactacaaa agcacaagaa gggctttatg tatatgatac
    22681 tgttcaaaga ctttatgata gccaatttgg aggagaaggt gtagatgata ttagcaagta
    22741 cataaaatat ggtaaactag gagaggcctt tagctcaaat caacaagtaa ttcttttaat
    22801 agatgaaata gataaggcgg atttagaatt tccaaatgac ttgctttggg aattggataa
    22861 aatggagttt tacataaatg agacaaaaga aactgtaaga gctaaacaaa gaccaatagt
    22921 tattataact tcaaatgcgg aaaaagaact tccagatgct tttttaagaa gatgcatatt
    22981 tcattatata gaatttcctg atagagacat gatggaagaa atagttaaag tacattttga
    23041 taaagtagaa gaacacctat tggaacaagt aatgactact ttttattgga ttagaagttt
    23101 aaaggacata caaaaaaagc ctagtacatc agagttaata gactggatac aagcattaac
    23161 tttgagtgga atgcctattg aaaaaataga aaaagaagtt ccttttgcag gaatactact
    23221 taagaataat gaggatattg aatctatgca aagacactta tagttaatag gagctggata
    23281 attatgttta ttgaattttt ttatttattg aggtcaagag gattaaatgt atctttaaat
    23341 gaatggatga ctttaattga agcattggat aaaggactgt gctattcaaa cttttcaaat
    23401 ttttactatc tttgcaggat gattttaata aaaagtgaaa gtgattttga taagtttgat
    23461 gcagtgtttt tggagtattt taaaggtata gaacaccaag aagaaattcc agaagagatt
    23521 atgaattggc ttaaaaaacc agatatagat ttagaagagt ttgaaagatt agaacaaaat
    23581 ccaaatataa atcttgataa attaagagct aaattggagg aacgaataaa agaacaagat
    23641 tctcctcata atggtggtaa ttattggata ggcacaggag gcacttcaga gttaggacat
    23701 tcaggaaaag ggcaaactgg tatacgtata ggtggaaatt ctacttatgg tagagctgtt
    23761 cttgaagttg caggagaaag aaaatataga gattttagag atgatgaagt tttaaatatg
    23821 cgtcaatttc aagttgcact aaagagactt cgtcaatttt ctactagaat agatgctcca
    23881 aagacagagc ttgatttgga taagactatt gaagagactt gtaataatgc aggatattta
    23941 aagttatttt ttgagaagcc aagaaaaaat acagtgaagc ttttattgct tatggattca
    24001 ggtggttcaa tgagagggta tagcacttta tgtaatacat tatttcagtc tgtaagtaaa
    24061 tcaaatcatt ttaaagatgt aaagatatat tatttccata actgtattta tgatagatta
    24121 tttacaacac ctgaatgttg gttaagtaaa tctattaata ctgaatggat attaaaaaat
    24181 atagataaaa actataaagt tataattgtt ggagatgctt ctatgtcgcc ttctgagttg
    24241 cttcatattg gtggtaacta tcgtggtcca tataattaca cacctggtat agagtggctt
    24301 aaaaggttta agagaaagta cagtaaaatt gtatggatga atccagaact tagagatgga
    24361 tgggattcaa ttaattattg gtatcaaact caaagaatga tacaaagtga atttaatatg
    24421 tttccattga ctgtaaaagg tcttgagaaa gcattgaaaa atttaatggt ttcaagataa
    24481 agtaaatata aatgatggta tgatttattc aaaattgtac catcattatt tattttttta
    24541 atatacctat tataaattgt ataactgaaa cttaaaaaat tatatagtct aatacatttt
    24601 agactcacac aaaacatata cattaataat aattttagaa gtcgaggtga ttataataaa
    24661 ttatgaatta attgtaaaat acaatggaga tatattgagg ttagaagaag aattaggtgt
    24721 atcagtagag atacttaatt catcatatgc aataataaca tcaagtaatg aagaagatgt
    24781 aaatatactt ttaacttatc cagaaattga atttatagaa aagcctttta tattacagac
    24841 tcaggatgtg caaagttttt caagtacagg aataacagga tttaaaaata gaactggttt
    24901 aactggaaaa ggaactataa ttggtataat tgattcggga atagattata ctctacctgt
    24961 gtttagagat agtgatggaa ggtctaagat attatattat tgggaccaat ctattcaagg
    25021 aaatccacca gaaggtttta gagaaggaac attatatact aatgaagata taaataatgc
    25081 aatagatgga agtatgtata tacctatttc aacaactagc ttacatggga cacatgttgc
    25141 aggtatttgt gcaactattg caagtgatgc cagaataata gtggttagag ttggaaatat
    25201 acaaaccgat attttttcga gaagtacaga gtttatgagg gcaattaaat ttattttaga
    25261 tagggcatta gaattaagaa tgcctgttac attaaatata agttatggaa gtaatgaagg
    25321 ttcacataga ggaacatctt tatttgaaca atatatagat gatatgtgtt tattttggaa
    25381 aaacaatata gttgtagcag ctggaaataa tgcagataaa ggaggtcata aaaggattag
    25441 gcttcaaaat aatattacag aagaagttga gtttatagtt ggggaaggag agcgtatatt
    25501 aaacataaat atatggccag attttgttga tgattttagt gtacatttgg taaacccatc
    25561 aaataatcaa acacaagcaa tctctctaac ttcaggtgag ataaggaata ctttgggtga
    25621 aactagaata actggttatt tttaccctat agcaccgtat tctctcacaa gaagagttac
    25681 tctacaatta agttcaaata cacagataac tcctgggtta tggaaaattg tatttgaacc
    25741 aatagatata gtaactggta atgtaaatat atatttgcca acttctgaag gtctaaatag
    25801 aaatactaga tttctgattc ctactcaaga gcttactgta acagttcctg gaacagcaag
    25861 tagagttata acagtaggta gttttaattc aagaacagat atagtatcta tattttctgg
    25921 tgaaggagat acacaattag gtgtttttaa acctgattta ttagctccag gtgaagatat
    25981 agtatctttt ttaccaggag gtacaagtgg agcattaact ggaactagca tggctacacc
    26041 tcatgttaca ggggtttgtt cattgtttat ggaatgggga attgtaaatg gaaatgattt
    26101 atttttgtat tcacagaaat taagggcatt acttctaaag ggagcaagga gattaagtaa
    26161 tcaatcttat ccaaataatt catcaggatt tggtttttta aatttatcag atatagattt
    26221 gtacactcta tctaatataa atcaagattt agaaacagag gatattggat atagaagtat
    26281 taataagtca tttaaagatg aggaaaatag ttataagttt atagatggtt ataatatgca
    26341 aatacataat gacttagaga atgaaattta tataagtaaa aatgcaagta gacaatcagg
    26401 aatactatca ggaatagata tagtccatac tcctgaattt gaagaagaac tagctgggtt
    26461 aggtatgagt caaaggtttt ttaagataag tgattcatta ggtgtactat ctataaataa
    26521 tacagactat aatagcatac aacgagtttt gcaacttcct tcaatcataa gaactgtatc
    26581 gactacaaag atgacattac ttggagaaat taatcgaggt acttttggag gtgtagttgc
    26641 aacagaagaa atgggcgtaa atttctttaa aaataatcct aatattaata taacaggaag
    26701 agggactcta atatcaattg cagatacagg aatagactat ctacacccag attttattta
    26761 tccagatggc acttcaaaaa tagtatattt atgggaccaa acaaaagaag gaactcctcc
    26821 tgatggtttt tatattggga cagaatatac acgagaagat ataaatcgag ctatcgcaga
    26881 aaatgaccct agtctatctc aggatgaagt tggtcaagga actatgttga gtgggatatg
    26941 tgcagggctt ggaaatgtaa atagtgaata tgcaggtata gcagaagatt ctgagctaat
    27001 aataataaaa ctcggcaaga tagatgattt ttataatagt gcaatgctgt ttgctgcatc
    27061 tcagtatgca tataaaaaag cttttgaact tggaagacca ttagttataa atatgtcttt
    27121 aggtaccagt agcctagcag gtttaaccaa taggagtaat agtgaaaaag cgttctttac
    27181 tagagggtta tgtataacgg caggagcagg aaatgagggc aatacacaga cacatacatc
    27241 tggaataata ccatatgttg gaggttctgt tgaagttgaa ttagagttaa atgaagatga
    27301 ggaagaatta tcattagaac tttggttaaa tagaccagat aaagctgatg taataatagt
    27361 atctcccact ggtgaagaaa gtaaaagtgt tggaatttca aattataata aagtaacagg
    27421 tttatttgat ttagagggga ctgaatattc tataacatat atatacccaa caactttttc
    27481 tggacagcaa tttactaatg ttactttaaa gaatgcaaaa agaggtgtat ggaagattcg
    27541 attagtagga gtttatatta taacaggaag atataactta taccttccaa atagagaact
    27601 tttaaaaagt ggaactagat ttagagaggt agaccctttt tacactataa attatcctgc
    27661 gattcaagat gatttaataa ccataggagc ctacaatact attaatggta gtttatggca
    27721 aagttcatca agagggccaa ctattgaaga caggttaaaa ccagatatag tagcaccagg
    27781 tgttaatata atagctgctt atcctgggaa cacgtatgca actataactg gtacagcagc
    27841 agcaagtgca catgcagctg gtgctgctgc aatgtatttt caatatactt ttgttgacgg
    27901 tagatatcca aaccaagcat atgtgcaaaa aataaaaact tttatgcaag ctggtgctag
    27961 aaaagattca aacacagtat atccaaatac aaattctgga tatgggctct tggatgttag
    28021 aggaatgttt gatgttttaa gataggaggg atttatggaa aaatcttatt gtataattta
    28081 tcaaggtgat atagaatctg ccctacaaga aaatggaata aataggtata tggttttaaa
    28141 tagtcagctt gcagtaatat atgtaccttt agattttgat gaaactattt taaataatat
    28201 aatacaagtt gcttggtggg aagaatctga accaatgagc agtctaattg aaataactaa
    28261 taatgtaaat aatggagaaa ccattacaac agcagctgaa actgattata tttatgaaaa
    28321 tccatataat gatataacag ggagaggaat tttattagca gttatagatt ctgggataga
    28381 ttatttgcat cctgatttta taaatgatga tggaactagt aaagttttat atttatggga
    28441 ccaagaagca aatacaaatc cacctccaga aggttttatt tttggaagtg aatttacaag
    28501 aagtgagtta aatatagcca taaatagaaa tgatgggagt ttgagtcaag ataatatagg
    28561 tactggaact ttagtttctg gtatattagt tggaaatgga aggataaatt ctcagtacag
    28621 aggtattact acagaatcag acttaatagt agttaaatta aaatcatata cagatactta
    28681 ttatgctgga aggataaatt acagtgtttc agatttttta gcagctataa cgtatgttac
    28741 taacatagca agaacagaaa ataaaccact gataataaat ttgactattg gagttaagtc
    28801 aagtgctgta gcaactactt caatactaga tacttttaat atattgagta gtgctggtgt
    28861 ggtagtagtg agtggtgcag gaaatcaagg gaatacagat attcattatt ctggcagatt
    28921 tagcagtgtg ggagaagttc aagatgtaat aatacaagat ggagatgact atgctcttga
    28981 tataacacta aatacgaatg gtccagataa agtgggagca cagataatat ctccttcagg
    29041 tgaagttagt catgatataa ggtattctcc agacttttat atatatagag gaaaatttaa
    29101 cttagaaaat actacttatg caatgagatt tatttatcca tatattacct ctggaaaaga
    29161 aaatttggag ataagattaa gagatataaa acctggagta tggattttaa gattgacttc
    29221 agaacttata ataaatggag aatatgacat atacttgcca aataaaaatt tgatagctcc
    29281 agacacaagg tttttagacc ctgattcagt agctactata actatgtatg ctgctagtga
    29341 tgatgtaatt acagttggta catttaacaa taagactgat agtatgtgga ttggttcttc
    29401 gaaaggacca attagaggaa gaggaattaa gccagatata gtagcttcag gtgtagatat
    29461 aatatccaca tataaaaatg gaacatataa tacaggaaca ggaacaggag tgagcagttc
    29521 tatagtcaca ggtgttttag ccttattgat ggaatactta gaaaaacagg ataatgtacc
    29581 gagattatca ttgtttacac aagttttaaa aacatattta atattgggtg ctacaaaact
    29641 tgagatatat acatatccaa atgtatcgca gggatatggg attttaaatt taaaaaatac
    29701 gattcaacag atagcaaata ctctatagat aagaacctat gtaaaattat aattgattat
    29761 tagtttaatt gtatcaaata ctttagatag agtagaaaaa tagcataaaa aataaatatg
    29821 aaaattaaaa aacagtttta tattttgaat acacaaagta aatattttgt atataaatag
    29881 gtataaatta agtattgaaa agatatgatg ttaatttaaa aataattata atttagactt
    29941 atgaatttta tttgtaaaat tgctaaaact attacaaaat aaataataga ggtgatagtt
    30001 ttggaaagta aaaaggcaag agcattaaaa ggtaaagata ataaaagact taaaagttca
    30061 cttttagttg gaaatgagtc gacagcagca tgggctgatg ttgaaaaatt aaaacctcat
    30121 agtaaagttt caataccttc aattaagggt gtcgaagaag caaaagactg ggttgacaat
    30181 ggaagtaaat tataaaattt tggaaattga agtaataaag aagtaatgaa gataagtatt
    30241 tattatcatt atgtaaggta gaattattat attttaaata acaatcagta tcaattatat
    30301 aaatttattg actaaaaatt tataaattgg tataattttg ttaattagca gaaataataa
    30361 aagataaata ctgtgaagag aagagtagat ataaaatgta gttctagcga gttgaggatg
    30421 gtgaaagctc aatacgaggt ttatattgaa gaacatcttg gagtttctaa tcgaaagctt
    30481 atttagtaag tagacttaga cggaaggcac cgttataggc tttaagcatt gcttaactaa
    30541 gaggtcatta tgacaactag ggtggtaccg cgagagtaat agtctttcgt ccctttatat
    30601 agggatgaag ggcttttttt attgaaatta tatttaaaag aaattaataa caattatact
    30661 aggaggattt aaaatgcaaa aggaatttat aacagtaaaa gaattgtaca gagaaaaaga
    30721 acagtacata gggaagactg taaaagtagc tggatggata agaacatcta gagtatctaa
    30781 aaattttgga tttatagagc taaatgatgg aagcttcttt aaaaatatgc agatagtatt
    30841 tgatgagaaa gtagaaaatt ttaaagaggt aggaaaatta gcaataagct catctatact
    30901 tgtagaggga gagttagtat ctacagaagg ggctaaacaa ccagtcgaaa tacatgcaaa
    30961 aagcatagtt gtagaagggg aatcagatag ttcatatcca ctacaaaaga agagacatac
    31021 gcttgaatat ttaagaacga tagcacattt aagaccaaga agtaatactt tttcagctgt
    31081 atttagagta agatcaatag ctgcctatgc aatacacaaa ttcttccaag aaagaaactt
    31141 tgtatatgca cattctccaa tcataacagg tagtgactgt gaaggtgcag gagagatgtt
    31201 tagaataaca actatggatt taaatgatat tccaaaaact gaagatggca aaatagacta
    31261 tactcaagat ttctttggaa aagaggctaa tttaacagtt agtggtcaat taaatgccga
    31321 gataatggca ctttctttta gaaacgttta tacttttgga cctacattta gagctgaaaa
    31381 ctcttataca ggaagacatg cttcagaatt ttggatgata gagccagaaa tagtttttgc
    31441 agaccttgaa gataacatgg aacttgcaga agatatgata aaatatgtta taagctatgt
    31501 attagaaaat gctcctgaag aaatggaatt ttttaatagt tttatagata aaggattgtt
    31561 agaaaggtta aataagatag taaactctga gtttattaga ataacgtata ctaaagcagt
    31621 ggaattatta attgaatctg ggcatgaatt tgagtatcct gttgagtggg gatgtgacct
    31681 tcaaactgag catgaaagat atataacgga gcaaatatat aattgtccag tgtttgttac
    31741 agattatcca aaagatataa aagctttcta tatgagaatg aatgaagatg gtaaaactgt
    31801 tagagcaatg gatttactag ttcctggagt tggagaaatc gtaggaggtt ctcaaagaga
    31861 agaaagagaa gatgtattgt tagatagaat taatgaaatg ggattaagag aagaagatta
    31921 ttggtggtat ttagaactta gaaagtttgg tactgctact cactctggat ttggtcttgg
    31981 atttgaaaga ataattatgt atatgacagg tatgtctaac ataagagacg ttataccttt
    32041 cccaagaact cctaaaaatg ctgaatttta ataattatat ataataaaac ttatataact
    32101 ttaagtataa acactaaaat gacttgcata tttatctatt ttagagatat gcaagttatt
    32161 tttattgtac tataaatata taatttgatt acttttattt tgcgatataa tacttatagg
    32221 tttatgtaat agtatgtaac cttttaataa aatgcaacac aattacgtcc ctgttctttt
    32281 gcagtatata gagccttatc acaattactt ataaactcat ttaatgttat tgtctttcca
    32341 attttctttg tataaactcc aatactaaca gttacacatt ttaaaggaac atcatcacgc
    32401 tcaaaattgc aggactctat aatttttcgt aaacattctg atttaagttt agcatctgcc
    32461 tcattacagt taaaaataca tataaaaaat tcctcaccac catatcgtat agcatgttca
    32521 ttttcagaac ttgtaaaatc taaaattact ttggcaatat tttgtagaca atagtctccc
    32581 ttttgatgtc cataattatc attaaattgt ttaaaataat ctatatctat catcattcca
    32641 gttataggtt cttgatttgc atggctgatt aatttttttt gtagaatatc ttcaaggtat
    32701 ctacggttgt tcattttagt aaggtcatct gtcataactt tgtcgttaag taaattattt
    32761 atatgagata tttcttcata ttgttgacta attaaaagtt tatcatagta agtaaataca
    32821 cgatttctat atagcattgt agaaacaaaa atggcaaggg atgttataaa aaatgtgttg
    32881 acaatattac taaactcatt gcctggtata gtttgaatcc caggtaagaa taaattaaga
    32941 aacaaaaagc atcctccaaa aactattact gattctccaa attttaatac tgagaaagct
    33001 gcagctgcta acataatata actaaataca cttaggtcat ttccacctaa ctggtcaagt
    33061 agagtaatta cacaacccca taggcagaaa aaagtcacat aaattatcca taaatttata
    33121 taaaacgtac agcaatcctt ttttttattc caaaggtaag aaaatacaaa cataaagaca
    33181 gaagatacac aaaatagtgt tacatacata taaaaatacc attggcgtct tggtgtgaca
    33241 aaagggcctc cttctctagc tgagattgat atcatcataa ttatttgaga tattactatt
    33301 attatgcaaa tgattttacc cgtatgataa agataattgc agagttcttt ctcaacattg
    33361 tctttgtgtt ttttgtctag aggaaatcca aaaaattttt ttattttttc taagttcata
    33421 taagcctcca ttaaaaataa agcataaaaa taagtattcc tttctatcat tagatatttg
    33481 gaatacttcg tttatgattt aattatatca aaatatattg tgtgtaacaa tctaaaattg
    33541 tgatagataa aatttattag ataatgtcga gtaactttat tgattaatac tttattataa
    33601 ttaagattta cagatagttt actactgaaa ataaagaata gaataaattt aaattaagca
    33661 taataaaata taaataataa agttcgcatt aacaaactat ttaaatatca agacctgtta
    33721 aaaaacaaca gcaataaaca aataaaatag ataaatatat ccaattaagg tataattaag
    33781 ttttatatga tatagttata tttgataatt tacaatagta aaacttggag ggaaaaaatg
    33841 ggtgaaaaga aaataaataa tatgaattat tcacataata attattccaa aaagacaggt
    33901 gaaccaacta gaaaaataaa aaatagccat atcactctta aaagtaaaga agaaaaaatt
    33961 tgttctagtt gcaataaaga aaataatact aaggataatt actgtaaatt ttgtggaaat
    34021 gaactttatg aaatagcatc attaagacca cttgaaacaa aactagactt gaaatctaaa
    34081 ataaaagagc tttcatatca tgcaaataaa agaggtgtat ttttaacaac atttacaacc
    34141 atatttatat tgtttattat tgcattgata tttaaagcta ttataactat tcaatttaat
    34201 gatattagtt atttagtaaa tccagcacat ataatcctag ctctcaactt gggtcaaatt
    34261 agtgtatcta tgtctaccat gatgggttct gggtttataa atgccaatat aggtttgttg
    34321 atattactta taatccctat tttggtatta ttaatatcaa acctaatttt tatgagaaaa
    34381 agatgtagag attcaaaaac tgtattagca aattctttag gagttggaat tttttatgga
    34441 ttagttttag ctattttatc tatttttact aatgtaaaaa ctagttcaca tagtatgtta
    34501 gaatatggat atgcattaga atatagttat gaatttttta gtgttctttt aaatggattc
    34561 gtattagggt ttatatgtac atacataact acttat
//
LOCUS       DAEPHU010000042        34389 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 01A10CD0081
            SAMN05941466-rid12468953.denovo.042, whole genome shotgun sequence.
ACCESSION   DAEPHU010000042 DAEPHU010000000
VERSION     DAEPHU010000042.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941466
            Sequence Read Archive: SRR6291087
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 34389)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 34389)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068158.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 22:43:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,892
            CDSs (total)                      :: 3,805
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 87
            rRNAs                             :: 8, 1, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 55
            CDSs (without protein)            :: 55
            Pseudo Genes (ambiguous residues) :: 0 of 55
            Pseudo Genes (frameshifted)       :: 21 of 55
            Pseudo Genes (incomplete)         :: 28 of 55
            Pseudo Genes (internal stop)      :: 16 of 55
            Pseudo Genes (multiple problems)  :: 8 of 55
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..34389
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941466-rid12468953.denovo.042"
                     /strain="01A10CD0081"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            353..544
                     /locus_tag="KR231_002141"
     CDS             353..544
                     /locus_tag="KR231_002141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0004508.1"
                     /translation="MERLMELIERKFLKDVELLELEDIENVIECKMTQPYNAHYNEYL
                     VKVKNGDEVEEYFVYLKHR"
     gene            complement(633..1445)
                     /locus_tag="KR231_002142"
     CDS             complement(633..1445)
                     /locus_tag="KR231_002142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mrp/NBP35 family ATP-binding protein"
                     /protein_id="HBH0004509.1"
                     /translation="MADCNSCPSKGNCNSQSNCSIENNPNNKFGKIIGVMSGKGGVGK
                     STVTALLANKLNKMGYKVGILDSDITGPSIPRLMGVKNVKAYSDGSYIYPVENSNNIK
                     VMSINLMIDDENEPVVWRGPLLGGVVKQFYTDVLWEELDYLLIDMPPGTGDVALTVMQ
                     SIPISGIVMVSVPQDLVSMIVSKAVNMAKKMNINVLGVIENMSYIQCPDCSKKIKLFE
                     GESTEKFLDDLDLELLGELPMTKEIIDITHNGVTEISDDLDSILTNVVEKIK"
     gene            1867..3018
                     /locus_tag="KR231_002143"
     CDS             1867..3018
                     /locus_tag="KR231_002143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004452985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBH0004510.1"
                     /translation="MELRPRSAKLEEFDKVIELINYVFRISRNHKPTMMEEFPLLLSK
                     NNIENMIIISEDDKVVSDVNYLIQDVSIQGNRLKVAAIGGVCTHPDYEKRGYSSKILD
                     KVEEKMFYDGVDIVIISGTRSLYSRRNCSLVKSFYKYTIKPEDVKIAYEIVEFDETNF
                     EKDNDLDKMIELYNQNSTRFIRTRDEFQKLLHAATIAWGPIGYKKVFIKENNNIIGYL
                     IIRTIKKEDSTVGEVAEIGLNSVNVENILKYVANKFGLESLNYKVHVKNLKDQLKCNG
                     TKSLDYQQGTMKIINFTKLCDSLRSYFSQYVDFELLKYMEFKQVENKYIIKYKEEELV
                     IENLDKLNKLFFEKNEEQYNEFKHLKNIYEFATKAFPVDFPWTANLNYQ"
     gene            3136..3774
                     /locus_tag="KR231_002144"
     CDS             3136..3774
                     /locus_tag="KR231_002144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423639.1"
                     /note="Presence of a B(12) (cobalamin)-binding domain
                     implies dependence on cobalamin itself, in one of its
                     several forms, or in some unusual lineages, dependence on
                     a cobalamin-like analog; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalamin-dependent protein"
                     /protein_id="HBH0004511.1"
                     /translation="MDILDDIAECILNMGVDNIENLVKIAIDKNIDVEDIYEYGLNKG
                     MIGALDKFENKEYYLSEVIVCTDALNKGINLLKGTGKVKKKSKGVILMSVVEGDTHEI
                     GKNIVKVMVEATGYKVIDLGVNRKSEDIIEEAIKNNVDIIGLSSMMTTTMENMKSVID
                     ELNMIEIDKRPKVIIGGGPVSMEFAEEIGADGYSSNAPKAVKLINKLIGGEV"
     gene            3775..4797
                     /locus_tag="KR231_002145"
     CDS             3775..4797
                     /locus_tag="KR231_002145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase"
                     /protein_id="HBH0004512.1"
                     /translation="MFSDMTLLQYINSEDRGFFLPDMGTNGLFLINKKAYEVYDSVDL
                     QLELAKTMDKYFESDFIYSFCDGITFCETLGLDTLRPDYDFPSVLTHTITDRDKLRKL
                     DVPDPYTSGRMPLNIESLSVISKSIKKPLYESIQGPFTLAGQLAGATQLLRCIITDKK
                     FVEELLEFTTELVRRYAVAANKAGAKYISIAEPTSVTLSKDRFDEFIVKNLNKIYNEL
                     DCWKGMHICGDTRELLDNMLSCNIDAVSLDQILDYEEIAPMIPRDIVLIGNLDPIKLL
                     GRSKPDKIRRETLKLLKKMRRYDNFLCDFGCNCLNTTPVENLQAAIKAGRISYKELDR
                     IDIDEL"
     gene            4787..5407
                     /locus_tag="KR231_002146"
     CDS             4787..5407
                     /locus_tag="KR231_002146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0004513.1"
                     /translation="MNYNSNKNKYLLKDINLDDIFIDKNIVLKFLGYGNRKAPDTISK
                     IVEREIRNINDILDIKIYISEVDINKTPKECKKAFAVLYTIGDKIDFKMNDYMENCNM
                     MAGLALDKVGIVCLDCINEKIKMYLKGKYDSLKISHEIYPGDKDFEVERQKDIYNYVK
                     NKYNSIEIEINDYHQLSPIKSVAMLILMGDEENLESRCSKCPRKCF"
     gene            complement(5531..6217)
                     /locus_tag="KR231_002147"
     CDS             complement(5531..6217)
                     /locus_tag="KR231_002147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjjG family noncanonical pyrimidine
                     nucleotidase"
                     /protein_id="HBH0004514.1"
                     /translation="MKTYKFIFFDADDTLFDFKKSESHAFKKLLSEFDLEFNFENYIE
                     SYRNISDKLWLDLEKNIITLNELKLLRFELFANKISLDVDSETLSKMYLNFLGECTFL
                     IPGAIDILQYLKKKYTIVIITNGISAVQKKRLENSKIKEYIDGMVVSEELKISKPNPE
                     IFKYALKKFNCHDKSSALIIGDSLTSDILGGINSGIDTCWLNSNNSINYTNHIPTYEI
                     NTLIELKKLL"
     gene            complement(6231..6776)
                     /locus_tag="KR231_002148"
     CDS             complement(6231..6776)
                     /locus_tag="KR231_002148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBH0004515.1"
                     /translation="MNDLNLGEKIAEVRKKQNLSIRDLAKLADVTPSLLSQIERGLAN
                     PSVNSLKSIASSLNVPLFTFFVSEVDKKNLIVRHDNRKKVILPGSKEVIYEILIPDSS
                     GNLEFAIMDLAPNTSSCVDRITHNGDEIAYVLEGEVKLFMDDDEFTLSKGDSVKVPLG
                     TKHKWQNDSNSESKVIFAVIL"
     gene            7004..8251
                     /locus_tag="KR231_002149"
     CDS             7004..8251
                     /locus_tag="KR231_002149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntP family permease"
                     /protein_id="HBH0004516.1"
                     /translation="MQITTFGAIFGLLIAIILIIKKFQAVYSLMLGAFIGGLVGGANI
                     TQTVDFMANGAMNISPSILRALASGVLAGSLIKTGAVDKISEQIVKIFGEKRALFSIA
                     ISTMVLAGVGVNLDVSIITVAPIGLYIGRKLNYSKLSILLAMLGGGKAGNIISPNPNT
                     IAVADNFSVNLSSVMMANIIPAIIGVVITVILASILINKGNKVQSYEILEQREDLPSL
                     FKSLCGPIIAIFLLFLGNVSPIVIDPMIALPIGGIVTLIVTGNLNNSREYLAFGLSKM
                     QGVCILLLGTGTIAGIIQMSELQQSTIGALQFLNMPQFLLAPVSGILMSLATASSTAG
                     ATIASSTFHDAIINGGLSPISGASIVNAGSSVFEQLPHGSLFHTSAGSINMDIGERFK
                     LIPYEALIGIVMTIISTSIQLVL"
     gene            8338..10332
                     /locus_tag="KR231_002150"
     CDS             8338..10332
                     /locus_tag="KR231_002150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HBH0004517.1"
                     /translation="MNKKKIVIIGIIYSFLVVFSLTNMYVNMEYNLNVFEYIKKSLPF
                     TEEEKKWLEKHKNLIYSSDQSSPPLRYKGKEDGQYKGIIVDLINSLSIQIGRDFYFKP
                     NNWWKESFVNSIDDSIKFFDLIPSKERANKFIFTDPIYTLSANILKDKKSQDINSYMD
                     LKGKTVAIPEGDYSINFLKQKIQDINILLTPDIKTGVNHLMSGKVDAVVGDEPVLRYY
                     INNYGLSNKYSVLSNPIYTKKAVLAVPKQYEELVSILNKGIFKLQKNGVYKDLKKKWY
                     STYNEVDDILYERGIVPSIYLFIGIILISIYVFYSYTYLLKIEIKRKTEQVIENKKTL
                     EATFNSITDIIMLVDENNNIVESNKVLYDFMGEMSYKIADLISMIKGVIENTFSENTN
                     KTSEIEIHNKILKINTFPVEYKKNNTEYIVVLIKDITNDKIVEAKLLRENKMISIGQL
                     ASGVAHEIRNPLGIIRNNCYLLKDNVTMEEVNDCVKSIESNVDRASNIITNLLNFARI
                     SDDNLEHINIRNFIENIVKLQYKMLQLKNVEIKIDCEHNLVCYINGESLKHVFINLIS
                     NSIDAIHQDGKIIIYCYEKNYCLFIDFKDNGEGIKEDALKDIFNPFYTTKPIGEGTGL
                     GLYITYNEIKKNNGDISVESKLGVGTCFHIKIPLNKEVTI"
     gene            10332..11654
                     /locus_tag="KR231_002151"
     CDS             10332..11654
                     /locus_tag="KR231_002151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-54-dependent Fis family transcriptional
                     regulator"
                     /protein_id="HBH0004518.1"
                     /translation="MKILLVDDELEYGVVMKKILQKKGYLVDIALSGEEAINIIKKDK
                     NYDLVLSDVMMKNMDGVQLLDRIKSINRDIEVILVTGYGSIENAVDAMKRGALSYFIK
                     SNPIENLLEEVEKVKASKISVSVQKNNLEFTLESKNRDFNNIIKIAKKAACKDVNILI
                     LGESGVGKDILARYIHSISPRKNEIFVPVNCCSFSENLLESELFGHEKGSFTGAVDSR
                     KGRFELSNKGTLFLDEIGDIPLNVQVKLLRTLEDKSIERIGSNKSIKVDFRLICAMNK
                     EPKVEISNGNIREDFFYRISTITITIPPLRKRREDLTTLIEFFLNKYQIEHDKKIHSI
                     DKEVKDFLLNYNYPGNIRELKNIINRLVVLSEEGNLSKDNLNLISNNVYIDDKISIRP
                     LREIRKEFECEYIEKVLSLCGNNISNTAKKLEISRRQLTNKISEYNIK"
     gene            11933..13219
                     /locus_tag="KR231_002152"
     CDS             11933..13219
                     /locus_tag="KR231_002152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006807454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine/sarcosine/betaine reductase component B
                     subunit"
                     /protein_id="HBH0004519.1"
                     /translation="MKLELGNIFIKNVEFGEKTEVKDGVLYISSEEIEKIVLEDERIV
                     SVNVELARPGESIRIAPVKDVIEPRVKIGDESKIFPGIINKVKTVGSGRTHVLLGACV
                     VTCGNIVGFQEGVIDMSGPTAKYTPFSKTNNICIVIKAKDGIDTHDYEEAARIAGLKI
                     GAYVGEAGREVEPDEVIVYETKPLLKQVKEYPDLPTVAYVHMLQSQGLLHDTYYYGVD
                     AKQIVPTFMYPTEIMDGAIISGNCVAPCDKVTTFHHLNNPVIHDLYKRHGKDLNFIGV
                     ILTNENVFLVDKERSSDMVAKLIEFLGVDGVLVTEEGYGNPDTDLMMNCRKCSEVGAN
                     VVLITDEFPGKDGKSQSIADATKEADAVVSCGQGNLVVHFPAMEKIIGTLDYVEMMIG
                     GYKGCLNEDGSMDAELQIIIASTIANGYNHLTARYY"
     gene            13305..14612
                     /gene="grdB"
                     /locus_tag="KR231_002153"
     CDS             13305..14612
                     /gene="grdB"
                     /locus_tag="KR231_002153"
                     /EC_number="1.21.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012158817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_except=(pos:14352..14354,aa:Sec)
                     /transl_table=11
                     /product="glycine reductase complex selenoprotein B"
                     /protein_id="HBH0004520.1"
                     /translation="MSKIRVVHYINNFFAGIGGEEKADIPPEKRAGVVGPGIAFQSQF
                     NDDAEIISTVICGDTYFGENIESATQELLKMIKEESPDLFIAGPAFNAGRYGVACGTI
                     CKAVEEELNIPVITGMYKENPGVDMFKLDLHIVSTGNSAASLRKVVPIMTKLGLKLVR
                     GEEIGPPEEEGYIMRGIRKNFFHELRGSERAIDMLVKKMKGESFETEYPMPEFDRVTP
                     MKPVKDLSKIKLALVTSGGIVPIDNPDKIESSSATKYGIYDLTDMDSMSNKEFTTIHG
                     GYDRAYVLENPNLVVPLDVVRELEKEGVIGELVDYFITTTGTGTSVGNSKRFGEEFSK
                     KLLEDDVDAVILTSTUGTCTRCGATMVKEIERAGIAVVHICTVVPISLTIGANRIVPA
                     VGIPYPLGNPMLGEEESKKIRKNIVLKALNALTEDIEEQTVFE"
     gene            14890..15621
                     /locus_tag="KR231_002154"
     CDS             14890..15621
                     /locus_tag="KR231_002154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBH0004521.1"
                     /translation="MIRKKVYILISIAICDDESYMLNHLKENIELYMKQKNLLYNIEL
                     FNKVEDLLCNHEKFNIVFLDIQMEEINGMQAARKLRSYGNECFIIFVTVLNEFVFDAF
                     EVDAINYLIKPLSNEKLYKTLDKIVTKLDDNESNYITIQKGYSYWKLKLADILYCEVI
                     KRKIYVHLKKETVDYYETIENLERSLPTNFFRCHRSYIINLQYVYGYENGNAVMESGD
                     RIPVSRLRQQIFSKVMLEFMKNRRI"
     gene            15623..16981
                     /locus_tag="KR231_002155"
     CDS             15623..16981
                     /locus_tag="KR231_002155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HBH0004522.1"
                     /translation="MINLFSSDLFLKYSFLFSFIVYRILMVIVQYYFLISFTNVNSKF
                     WCFILYSIISIFLIIINTYFNLYNLFSSQILFFLMTFLFVKYIIKQSTVLSIVSTLLV
                     YLIEQLVYGFTAPLNYLIFTSDINTDIYKFDINMGLSSLITIIIAGFIYWYSSKKFNI
                     KVMNFDKYIAILMIPLLLIILFMQSFEYSSNINIDTSLGIVKLLLNTSITEEIQAFLF
                     SIIGTICVFFSLFTFKKLIQALEDDKERAIMNQQIHAQKNYIEEAKSRLSQTISFRHD
                     FNNHLAIVNGLLKKDQILKAQDYLNKLEKVTSDLSFSCNTQNIVIDALFNNKLSIAKQ
                     LGIEVDCEVIIPQSTNMNDFDLCIVFANAIDNAIKACRVVDKQNRYLKLSTKLEGGFF
                     MIEIKNSYNPINNYTSGSGIGLLNIKEIAKKYQGAISIDKTSDYFQINVLLVISLHCA
                     SI"
     gene            17020..17505
                     /locus_tag="KR231_002156"
     CDS             17020..17505
                     /locus_tag="KR231_002156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0004523.1"
                     /translation="MYLNRESLIYRNEEVTKMKVGNINGQAPITNGLDSCQSEVQGLE
                     QKKKSLQDEIEKVRSDKSIDGETAKLKIEALKKEMEEIENKIQELKGNKAKKTNKEEN
                     NVSEVNNNLLERKKEPSNNENVKQLYDVFERSNVDEQWDNTYRVLQDDKNLKVKFNRP
                     I"
     gene            complement(17768..18004)
                     /locus_tag="KR231_002157"
     CDS             complement(17768..18004)
                     /locus_tag="KR231_002157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0004524.1"
                     /translation="MLLTHIYFNGQFKQTIELYKQAFNATVKTLIEDSCYLLIVHNEI
                     VIHNKFLILNDFGNKNGVSISEGYQPTDKIQTAS"
     gene            complement(18159..18383)
                     /locus_tag="KR231_002158"
     CDS             complement(18159..18383)
                     /locus_tag="KR231_002158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrous iron transport protein A"
                     /protein_id="HBH0004525.1"
                     /translation="MTVYNLKLGQKGIIDNIAGNEKLMKRLLALGLIDGTEVEVKKIA
                     PLNDPIVIRFRGFDLAIRKSDAKNINLKNN"
     gene            complement(18480..19733)
                     /locus_tag="KR231_002159"
     CDS             complement(18480..19733)
                     /locus_tag="KR231_002159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:glutamate symporter"
                     /protein_id="HBH0004526.1"
                     /translation="MITLSFDIVQTLTLSIFFFLIGNLLKNKVNFLNNFCIPAPVIGG
                     LLFCFLNLFFKYFNIADISISGNLMPNFITFFFTTIGLEISINLIKKGGSVLFRYWIL
                     CGVLAFCQNILAITISKIIKLEPLLGLMCGNVSMEGGHGYSAAFGLTIENLGIEGAVG
                     VGLSAATIGLIMGGILGCPVAKFLINKYKLKPSSNIDLSIPRYNRNLKRFGSKFFRNK
                     NRIKNNNFSETITPSVFLEQVLLIFICINTGEIISRCFYITFNILLPSVVTCMFSAVI
                     FRNLNDKINILELNFKLIDFLKELSLGIFLTLSLMNIDLFELSTLLPPILLIVTFQVI
                     FIILFSIFICFRVLGKDFDSAIIISGLIGHGIGATPNALANMSSLTQKYGDSPKAFLV
                     VPLVSGFLLDAISIPCILFFINILT"
     gene            19993..20982
                     /locus_tag="KR231_002160"
     CDS             19993..20982
                     /locus_tag="KR231_002160"
                     /EC_number="3.5.4.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenosine deaminase"
                     /protein_id="HBH0004527.1"
                     /translation="MFENLPKIDLHCHLDGSVRVETMLDIAIKEKIDLPSNNMDEIKK
                     LAKVSFNCTSLDEYLEKFDLPLKVMQSKENLKRITFELLEDASRENVKYIEIRFAPLL
                     HTQKGMSVKNIIEGIIEGIREAESIYDIKGNLILGCMRTMTSKEALLVIEEGKSFVNK
                     GVVAVDLCGPEKEGFCKEYKDVFKLAREYGYKVTIHAGEAASGENVLDAINILKADRI
                     GHGVKIKDHKKAYNLVKDKKILLELCPTSNVQTKTVDSYEAHPFYTFYKDNLHVSINT
                     DNRTVSDINLSSELNVIFDTFKLGLEDYKIIYRNAVEASFADKETKEYLNSLI"
     gene            21054..21794
                     /locus_tag="KR231_002161"
     CDS             21054..21794
                     /locus_tag="KR231_002161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EcsC family protein"
                     /protein_id="HBH0004528.1"
                     /translation="MKDYEDVVYIKLVKKELEEWKKNILKKPSIFDKASKGIQNKFNG
                     VLPDKYHEIITSSIKVMTKTVLFGYKYATKPPLRNMSLEEREKLVLEKAKTYKTTAMI
                     EGAGTGAGGILLGLSDFPLLLGIKVKFLYDVASIYGYDVKDYRERIYILNILQLAFSS
                     QQHINKTFKLMNNWDEYVNSLPEDINDFDWRTFQQEYRDYLDLAKFLQLMPGIGAFVG
                     FYVNGKLIDKLCETAVSAYRLRIRELKL"
     gene            22010..23161
                     /locus_tag="KR231_002162"
     CDS             22010..23161
                     /locus_tag="KR231_002162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-hydroxyacyl-CoA dehydratase"
                     /protein_id="HBH0004529.1"
                     /translation="MTNLPKQFDSFNEARQKGFINAKELKESGKKMVGVFCTFTPVEI
                     PMAAGATVVGVCGVSEEPIPDAERVLPRNLCPLIKSSYGHAITDTCPYFYFSDLLIGE
                     TTCDGKKKMYEELAKVKPTYVMHLPNTSKGEFAYKLWKDEMIRLKEEVEKSLGVTITE
                     EDIRTAIKDKNEERELLKEFYALGKLQPSALTGLELHNVLYQAGFKFDRAELKHSLRK
                     VIDDMKERYEKGECPVQKDKPRILITGSPIGGISEKIVKTLEDAGASVVAYELCGAIR
                     SNDLLVDEEIEDVYDALTQKYINIGCSCMMNNDNRIELLDRIIDEYNVDAVIDVVLQA
                     CHTFNIESYRIREFVTKEKNKPFMSLETDYSKSDTEQLRTRFEAFVEML"
     gene            23186..23941
                     /locus_tag="KR231_002163"
     CDS             23186..23941
                     /locus_tag="KR231_002163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-hydroxyglutaryl-CoA dehydratase"
                     /protein_id="HBH0004530.1"
                     /translation="MFSIGVDSGSVATKGVLFDGEKIIKKIIIPTGWSPKSTSKQVYE
                     LLSSEIDKKDIKKVVGTGYGRGVMDFADKKVTEITCHTRGIYFLNKNIRTILDVGGQD
                     SKVINLDRDGNVFNFIMNDKCAAGTGRFLEITSNLLGSDIESIDTLAKGYEPVNISSM
                     CTVFAESEIVSLLAQNISTGEVAAGILKSIANKSTSMLARGEVIDEVAFTGGLAKSKE
                     LVKMIEEILGKKIFIAEDTQIIGALGAAVIGFR"
     gene            24133..26520
                     /locus_tag="KR231_002164"
     CDS             24133..26520
                     /locus_tag="KR231_002164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding cysteine protease Cwp13"
                     /protein_id="HBH0004531.1"
                     /translation="MKKFTSKKVTRFVALFLISILVMSTIPVSADNSNTLNQIKKAEY
                     SETYKQYLNDAKNGCTEKYNGIIPNPYQLEGTQIQSKGRTAPTSYDPRKLGLMTSIKN
                     QEDLGICWDFAAMATLESFLKLNNYGDYDLSEEHLRWWASDGEYGWSVNDMNGALNYE
                     AMGYLTSWSGPKLEKDIPYNGRVSKAQGAKKPTNMNTAPTVFNVTDAVCVSNDINSTK
                     NAILQYGAVTSGYYEDIKYQSDDQNSYYCPTKSFNTNHAISIVGWDDNYSKDNFNANI
                     RPSKNGAWLIKNSWGDYNSEGGYFWISYEDKTLMSDIDNFSIKGGKKPNDDEKMYQHD
                     YASIVPLISKKITAANVFDFNRGDETLKSVMFLTESIGAKYEVYYAPVVNGIPQENNM
                     KKLKEGTAQYSGYITVPIDSFDIPEGKGAIVVSIEGKNGESTIGSESNVPGYDTFKAK
                     ANLGESYIIDNTGKFFDINRDSNFYPCNFTIKAVTEKSSGESIPNESLIGSDRYETAI
                     KVSQNGFNSSENVVLVNGSSIVDALAATPFTSAINSPILLTQKEALNSKTKAEIQRLG
                     AKKVYLIGGENSISKEIEQQLKSLNISIERISGSDRYKTSLLLAQKLNGIKNVSQIAV
                     VNGVKGLADAISVGAAAAENNIPIILANEKSELQGADEFLNSLNIEKSYIIGGTASLS
                     NNLESKLKNPTRLSGSSRDETNSKIIDNFYKKDTLKNAFVVKNGIKNQNDLIDGLAVG
                     PLGAKTGSPVILVGDKLADSQKEVLKNKTLEKVTQVGGGANKNAFKELVKLKSAK"
     gene            complement(26751..26984)
                     /locus_tag="KR231_002165"
     CDS             complement(26751..26984)
                     /locus_tag="KR231_002165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATPase"
                     /protein_id="HBH0004532.1"
                     /translation="MATTTKNRFYDYVQENLNKYVEVHSYFSSCPLYGEIIEADSLSI
                     TLCSRYIDESNPTLNETYTLYLPLSSIISIRTL"
     gene            27273..27863
                     /locus_tag="KR231_002166"
     CDS             27273..27863
                     /locus_tag="KR231_002166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBH0004533.1"
                     /translation="MPKSYSDKEREYIIKRLKEEARLCMEQYGIRKTTVDELVKRVKI
                     PKGTFYLFFQSKELLFFEVLRDIHDSIQKEILYEINRVDESITCEQLTDIFMKFYRMV
                     DSTSILNLMINGEFEILVRKLPDSIIEEYFRHDDFEIGEIISCIPNAKNKDIESFSGA
                     FRAVFLTMLYKREVGSNCFEDALRLMINGLVIQLME"
     gene            27977..28822
                     /locus_tag="KR231_002167"
     CDS             27977..28822
                     /locus_tag="KR231_002167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH0004534.1"
                     /translation="MIKVDDLSFSYTDRDFLQNINFEVGKGEILGFLGPSGAGKSTLQ
                     KILIGMITNYGGSVIVNGVESKRHSNKFYENIGVDFEFPSLYEKLTAIENLKYFGSLY
                     SKKLLSIDELLKSVGLENESNKRVSEYSKGMKSRLNFIKALLHNPDILFLDEPTSGLD
                     PSNSKVMKDIILSEKSKGKTIILTTHNMLDATELCDRVAFIVNGKISALDTPHNLIMS
                     KGAIKVRYTYFDNGEKTSECFLNNTANDKNLNMLIEKNKLLSIHSSEPTLNDIFIEIT
                     GRNLQ"
     gene            28819..29502
                     /locus_tag="KR231_002168"
     CDS             28819..29502
                     /locus_tag="KR231_002168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBH0004535.1"
                     /translation="MRLKNLILGDIKFQFKYGFYFLYLFLSIIYICIINVFPTFMREK
                     IAIIMIYSDPAAMGLFFMGAIVLLEKSQRVLNSLAVSPVKVSEYILSKVISLGVISSI
                     VAMFIAITLNLDNIIISTIGTFFSSIIFSLLGLIIASKASSLNQFIVLSIPIEIICFI
                     PPILNVLLDTKSYANLYPFNICISLISGDKNFIMINILILISIIIIIYFITYYFICSS
                     WKKVGGVKL"
     gene            29499..30215
                     /locus_tag="KR231_002169"
     CDS             29499..30215
                     /locus_tag="KR231_002169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902755.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBH0004536.1"
                     /translation="MIKIINAFKQEFEQIKRDAMLFIVCVSPILCGVFIKFGIPLIQN
                     ISLNKFYYQLNLEPYFLMFDLLLAFITPFMFFFASTMVILGEIDDSISRYLIVTPLGK
                     TGYLISRFGIPGILAFIITMILLIFFSLTKISLLLNLSISLLVLLQGVIISILVISLS
                     SNKLEGMVITKFSGVFMMGILAPFFILNKAQYILFFLPTFWISKAFKEDNYVYMFISI
                     VISLIWILLLFKKFSKKIVK"
     gene            30312..30575
                     /locus_tag="KR231_002170"
     CDS             30312..30575
                     /locus_tag="KR231_002170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBH0004537.1"
                     /translation="MKNKIKILREKLGLTQEQLGRLVGTSRQAINAIETGKNEPSIWL
                     AYDISRIFNEPIESVFLFEESERKSRAQISRGEYYGYKKDKNI"
     gene            30547..31002
                     /gene="def"
                     /locus_tag="KR231_002171"
     CDS             30547..31002
                     /gene="def"
                     /locus_tag="KR231_002171"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HBH0004538.1"
                     /translation="MAIRKIRTFDDEILRKKSKYVENVDNKIREILNDMAETMYNTPN
                     GGGLAACQVGVLKRLVVIDLGEGLIKLVNPEIIEQEGEQIVVEGCLSFPEVWGKLKRP
                     KKVTVQALNEYGEKIEIKGSGFMAKCLCHEIDHLNGIVFTDKIIEHVKL"
     gene            31054..31515
                     /locus_tag="KR231_002172"
     CDS             31054..31515
                     /locus_tag="KR231_002172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrimidine dimer DNA glycosylase/endonuclease V"
                     /protein_id="HBH0004539.1"
                     /translation="MRLWHKDLIDVLPKNQLVSQWRELLAIKGSIDKKGTPNHLLVNK
                     VLNYSIDEFKFYTKIVHDEMLKRNYKPNELKYTSILKWKNRNFANDISNEHSLNLENL
                     YDDWHNKMYLKQCLYNLEEKATCGGIPINEWNILLCKYSKDYELWSGNIMF"
     gene            31565..32467
                     /locus_tag="KR231_002173"
     CDS             31565..32467
                     /locus_tag="KR231_002173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM protein"
                     /protein_id="HBH0004540.1"
                     /translation="MYNKIKYIPINCEIACNKLKRSMPYKWDLNIYRGCEHGCKYCYA
                     IYSHKYINSNNYFEEIYVKTNIVEKLERQLKSSKWKKEVINIGGVTDSYQPIEADYKI
                     MPEILNLLIKYKTPAIISTKSDLILRDYDLIDKLSRITYINVASTITTVNEDTQRLIE
                     PNGVDSMRRFKMLKEFRKTNASVGLHIMPIIPYITDDFDNINSLFRHAKECNVHYVLP
                     GTLYLRGITRGVFFDFVKKEFPELFDKLSILYSAGSLNREYKNQLYKMVNELRYKYSL
                     SSSYSKIMKEKLKNSGDVQISFFD"
     gene            32837..33649
                     /locus_tag="KR231_002174"
     CDS             32837..33649
                     /locus_tag="KR231_002174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HBH0004541.1"
                     /translation="MYLERPELYKQSEINFWDDEYISKQLLKAHLDTNFEGASRNFNF
                     IEDSVNWIVTVANPANYPKLLDLGCGPGLYAEKFAQKGYKVTGIDFSKRSINYAQNRN
                     KETNLNINYLFQSYLNMNYNEEFDLATLIYCDYGALSTENRRLLMEKIYDSLKPGGKL
                     ILDVFTINKYNNFEEIKYWEINEDGGFWSNEKYMCLQDNCKYNDYNTLEQTLVITEKD
                     ENVFYVWNHYFSKESFLLEVENIGFKSVEFFSNVKGEAYSDDSMTMGLVLQK"
BASE COUNT        13710 a         3553 c         5621 g        11505 t
ORIGIN      
        1 ctttatttaa aaaattagta aaagtatatc cacttttttt cttaaacaaa gaaaaaataa
       61 cttttattaa gttgtaattc attacatata ttacttactg ttatatcttc tgagtaattt
      121 ttgtgaatat aatttatagt tttctttaag ttttctttac ataaaactaa gagttggtct
      181 atgtttcatt ttatcaaggc atatttatta aaaaatcaat ctctatttgt taaaataatt
      241 tatgaatgat gttagaaact gtaatatatt ggatataata taataaacag ataaactctg
      301 cattaagagg atatatagtt tatcttaatt ataggggaag tgaggatata ttatggaaag
      361 attaatggaa ctcatagaaa gaaaattttt aaaggatgta gaacttttag aattagaaga
      421 catagaaaat gtaatagaat gcaaaatgac acagccatat aatgctcatt ataatgaata
      481 tttagtaaaa gtaaaaaatg gagatgaagt agaagaatat tttgtgtatt taaaacatag
      541 ataaacataa aagaggttta tatttatttg tatgattata aaataaatac aagcctcttt
      601 ttttgataaa tataaaatta taaaattttt atttatttaa ttttttcaac aacattagtc
      661 aatattgaat ctaaatcatc actaatttct gtaactccat tatgagtaat atctataatt
      721 tctttagtca taggaagttc tcctaaaagc tctaagtcta aatcatctaa aaacttttca
      781 gtagattctc cttcaaataa cttgattttt ttagaacaat caggacattg gatataactc
      841 atattttcaa taactccaag gacatttatg ttcatttttt tagccatatt aacagctttt
      901 gatacaatca tagataccaa atcttgaggt actgaaacca taactattcc acttatagga
      961 atagattgca taactgttaa ggcaacatct ccagtaccag gaggcatatc tattaataaa
     1021 tagtctaatt cttcccaaag tacatcagta taaaattgct ttacaacccc tccaagtaaa
     1081 ggtcctctcc aaacaacagg ttcattttca tcatctatca taaggtttat agacattact
     1141 tttatgttat ttgagttttc tacagggtaa atataagagc catcagaata agcttttaca
     1201 ttttttacac ccataagtct aggaatactt ggtccagtta tatctgagtc taatatacca
     1261 accttatatc ccattttgtt tagcttatta gcaagtaaag cagttacagt tgattttcca
     1321 actccaccct tcccactcat aacaccaatt atttttccaa atttattgtt agggttattt
     1381 tcaatagaac aatttgattg actattacaa tttccctttg atggacatga attacaatct
     1441 gccatatcta ttacctccaa actttaatat ttattagatt atttgtaacc tacatatact
     1501 attttagtac aattgaacca taaagtcatt atttaaaagc aacttagaag attttctatt
     1561 gatttattca tagactatag caaaaagaat acaataaaaa aattataaca ttcttgaaaa
     1621 agtgattatt tcaatttagt tatagaactt agtcatataa atatatagaa aatattttaa
     1681 tatattatac ataacgggtt attttataag tttaactata aattaggttt atattttata
     1741 aaaatttgct aaaaaaaaca attaaaaatt gtaaagaaaa aagatataat tagaactgta
     1801 gtaataaatg ttttattata gataatagag ttttaagtat cttaaataat atttggagga
     1861 atatgaatgg aattaagacc aagaagtgca aaattagaag aatttgataa agtaatagaa
     1921 ttaataaact atgtatttag aatatcaaga aatcataaac caactatgat ggaagaattt
     1981 cctcttttac taagtaaaaa taatatagaa aatatgatta taatatcaga agatgataaa
     2041 gtggtttctg atgtaaacta tctaattcag gatgtatcta ttcaaggaaa cagattgaag
     2101 gttgcagcta taggtggagt atgtactcat ccagattatg aaaagagagg ctattcatct
     2161 aagatattgg ataaagtaga agaaaaaatg ttttatgatg gtgtagatat tgtaattata
     2221 tcaggaacaa gaagtctata cagtagaaga aattgtagtt tggtaaagag tttttataaa
     2281 tatacaataa aacctgaaga tgtaaaaata gcatatgaaa tagttgaatt tgatgaaact
     2341 aattttgaaa aagataatga tttagataaa atgattgaac tatataatca aaatagtact
     2401 agatttataa gaacgagaga tgagtttcaa aaactattgc atgcagcaac tattgcctgg
     2461 ggaccaattg gttacaagaa ggtatttata aaggaaaata ataatataat aggatatttg
     2521 ataataagaa caataaaaaa agaagattct actgtaggag aagttgctga aatagggtta
     2581 aactctgtaa atgttgaaaa tatattgaaa tatgttgcaa ataaatttgg attagaatct
     2641 ttaaattata aagtacatgt gaaaaatctt aaagaccagt tgaaatgtaa tgggacaaaa
     2701 tctttggatt atcaacaagg aactatgaaa ataataaatt ttactaagtt gtgtgatagt
     2761 ttaagaagtt attttagtca atatgtagat tttgaattac taaaatacat ggaatttaaa
     2821 caagttgaaa ataaatatat tattaaatac aaagaagaag aacttgtaat agaaaatttg
     2881 gataagctta ataaactgtt ttttgaaaaa aatgaggaac agtacaatga atttaaacat
     2941 ctaaaaaata tatatgaatt tgctacaaag gcatttcctg tagattttcc atggactgca
     3001 aatttaaatt atcaatagtt ttagatgata ttaaataaaa ttgattgata cctagagtta
     3061 gtccttgtta aataagagaa attattggat attgaaaaag caattttgta agtaattaga
     3121 aaggatgagt attatatgga catacttgat gatatagcag aatgtatatt aaatatgggt
     3181 gtagataata tagagaattt agtaaaaatt gctatagata aaaatattga tgtggaagat
     3241 atttatgaat atggtttaaa caaaggtatg ataggagctt tagataagtt tgagaataag
     3301 gaatactatc tttcagaagt tatagtatgc acagatgcat taaataaagg tattaatctt
     3361 ttgaagggaa ctggaaaagt aaagaaaaaa tcaaagggag taattctgat gtctgtagta
     3421 gaaggagata ctcatgagat aggaaaaaat attgtaaaag taatggtaga agccactgga
     3481 tataaggtta ttgacttagg tgtaaataga aaaagtgaag atataataga agaagctata
     3541 aaaaacaatg tagatataat aggcttatct tcaatgatga caactacaat ggaaaatatg
     3601 aaatcggtta tagacgaact taatatgatt gagatagata aaagaccaaa agtaataatt
     3661 ggtggaggac ctgtaagtat ggagtttgca gaagaaatag gagcagatgg atacagttca
     3721 aatgctccaa aagcagttaa attaataaat aaacttatag gaggtgaagt ttaaatgttt
     3781 tcagatatga ctttacttca gtatataaat agtgaagata gaggtttttt tctgcctgat
     3841 atgggtacaa atggattgtt cttaataaat aaaaaggcat atgaagtata tgatagtgta
     3901 gatttgcaat tagaattagc aaagactatg gacaagtatt ttgaatcaga ttttatatac
     3961 tcattctgtg atgggattac attttgtgaa actctgggtt tagatacatt aagaccagat
     4021 tatgattttc caagtgtatt gacacatact ataactgaca gagataaatt aagaaaatta
     4081 gatgttccag acccttatac gagtggacgt atgccactca atatagagag cttatcagtt
     4141 atatcaaaaa gtattaaaaa accactatat gaatcgatac aaggtccatt tacacttgca
     4201 ggtcaattag ctggagctac tcaactttta agatgtataa taactgataa aaaatttgta
     4261 gaagaattat tggaatttac aactgaattg gtaagaagat atgctgtagc tgcaaataaa
     4321 gcaggagcaa aatatatttc aatagcagag ccaacatcag taaccctaag taaagataga
     4381 tttgatgaat ttatagtaaa aaatttaaat aaaatctaca atgaacttga ttgttggaaa
     4441 ggtatgcata tatgtggaga caccagagaa ttattagata atatgctaag ttgtaatata
     4501 gatgcagtaa gtttagacca aattttagac tatgaagaaa ttgctccaat gattcctaga
     4561 gatatagttt tgattggtaa tttagaccca ataaaacttc ttggacgttc taagccagat
     4621 aagattagaa gagagacact aaaattgtta aagaagatga gaagatatga taacttttta
     4681 tgtgattttg gctgtaactg cttaaatacc actccagtag aaaatttaca agcagctata
     4741 aaggcaggaa gaattagtta taaagaatta gataggattg atattgatga attataatag
     4801 taataaaaat aaatatcttt taaaggatat aaatttagat gatattttta tagataagaa
     4861 tattgtgcta aagtttttgg ggtatggaaa tagaaaagct ccagatacaa ttagtaaaat
     4921 cgttgaaaga gaaataagaa atataaatga tattttagat atcaagatat atataagtga
     4981 agttgatatt aataaaacac ctaaagaatg taaaaaagca tttgctgtac tatatacaat
     5041 aggggataaa attgatttta agatgaatga ctatatggaa aattgcaata tgatggcagg
     5101 gctggcattg gataaggtag gtatagtatg tttagattgt attaatgaga aaataaaaat
     5161 gtatttaaaa ggaaagtatg atagtctcaa aatatcgcat gaaatatatc caggagataa
     5221 agattttgaa gtagagagac aaaaggatat ttataactat gtaaaaaata aatataatag
     5281 tatagaaata gaaattaatg attatcatca actatccccc ataaaaagtg ttgcaatgct
     5341 tattttaatg ggggatgaag aaaatttaga atcaagatgt agtaagtgtc ctagaaaatg
     5401 cttttagtta attttcaaga ctaagatttg ttttgtgtat aaattgcaat aatttttttg
     5461 gtcattttat gtataaacta aaaaaattat tgcaaagtaa tattctattt aatttgaaca
     5521 gacttacaaa ctatagtagt ttctttaatt caataagtgt atttatttca taagttggta
     5581 tatgattagt ataatttata ctgttattgg aatttaacca acaagtatct attcctgaat
     5641 ttattccacc taagatatca gaggttaagc tatccccaat tattaaggca gaagatttat
     5701 catgacaatt aaactttttg agagcgtatt taaatatttc aggatttggt tttgatattt
     5761 tcaactcttc agatacaacc attccatcaa tatattcttt tatttttgaa ttttcaagtc
     5821 ttttcttttg aactgcagaa attccatttg ttattataac aatagtatac ttttttttaa
     5881 gatattgtaa tatatcgatt gcacctggaa ttaaaaatgt acattcacct aaaaaattta
     5941 agtacatttt gctaagagtt tcagaatcaa catccaaaga tattttattt gcaaaaagtt
     6001 caaatctaag taatttaagt tcattcaaag ttataatatt tttttcaagg tcgagccaaa
     6061 gcttatcact tatatttcta tatgactcta tataattctc aaaattaaat tctaaatcaa
     6121 actcagatag aagtttttta aaagcatgtg attcactttt cttaaaatca aataaagtat
     6181 catctgcatc aaaaaatata aatttatatg tcttcatggt ttttactcct ttacaagatg
     6241 actgcaaaaa ttactttact ttcactattt gagtcatttt gccatttatg ttttgttcct
     6301 aaaggaactt ttacactatc tcctttggac aaagtaaatt catcatcatc cataaaaagt
     6361 ttaacttctc cctccaaaac atatgcaatt tcatctccat tatgagtaat cctatcaaca
     6421 caagaagaag tgtttggagc taaatccata attgcaaatt ctaaattacc actagagtct
     6481 ggaattaaaa tctcatatat aacttctttg cttccaggta aaataacttt ttttctatta
     6541 tcatgtctta ctatcaagtt ttttttatct acctcagata caaaaaatgt aaataaagga
     6601 acgtttagag aagaggctat agattttaat gaatttacag atggattagc aagacctcgt
     6661 tctatttggc tcaataatga tggtgtaaca tcagctagtt ttgctaaatc tcgaatactt
     6721 aagttttgtt tttttcgaac ttcagctatt ttttccccta aatttaaatc attcatataa
     6781 atatcctctc tttttaattt aaaaaatatt aacttaaaat aatcaagtaa aatgattatg
     6841 tagtatgaaa ttattataac atatagaatt aggttttgaa aaaactatgt tcaatataat
     6901 taaataaatt aaaatataat tgacaaagtg gatacagaat acttaaaata tatttaaata
     6961 aaattaagca aaagatagtt aatttatgat aggaggggat attatgcaaa taacgacttt
     7021 tggagctata tttggtttat taatagcaat tattttaatt ataaaaaaat ttcaagctgt
     7081 atatagttta atgctaggag catttattgg aggattagtt ggaggagcaa atataacaca
     7141 aactgtagat tttatggcaa atggagctat gaatatatca ccatcaattc ttagagcttt
     7201 ggcatcaggt gtattagctg gaagtttaat aaaaacaggg gcagtagata aaatatcaga
     7261 acagattgta aaaatatttg gtgaaaagag ggctttattt tcgattgcca tttcaactat
     7321 ggtacttgct ggagtaggcg taaatttgga tgtatctata ataactgtag cacctatagg
     7381 attatatata ggtagaaaat taaattattc taaattgtca atactattag ctatgttggg
     7441 agggggtaaa gcaggtaata taatatcacc aaatccaaat actatagcag tagcagataa
     7501 tttttctgtc aatctctcta gtgttatgat ggcaaatata attccagcaa ttattggagt
     7561 tgttattaca gttattttag caagtatatt aataaataaa ggaaataaag tacaatcata
     7621 tgaaatttta gagcaaagag aagatttacc aagtttattt aaatcattat gtggtccaat
     7681 tatagctata tttctattgt ttttaggaaa tgtatctcct atagttatag acccaatgat
     7741 agcccttcca ataggaggaa tcgtaactct aattgtcaca ggaaacttga acaattcaag
     7801 agaatattta gcttttggat tatctaagat gcaaggggta tgcatattat tacttggaac
     7861 agggactatc gcaggaatta tacagatgtc tgaattacaa cagagtacaa taggtgcttt
     7921 acaattttta aatatgccac aatttttatt ggcaccagtt tcgggtatac ttatgtcatt
     7981 agcaacagca tcatcaacag ctggtgctac tatagcatca tctacttttc atgatgctat
     8041 aataaatggt gggctatcac cgatttcagg tgcctcaata gtaaatgctg ggtctagtgt
     8101 attcgagcaa ttaccacatg gctcactatt tcatactagt gcaggtagta taaacatgga
     8161 tataggtgaa agatttaagt taattccata tgaagcattg ataggaatag taatgactat
     8221 aatttcaaca tctattcaat tagttttata ataaatataa atatttaatg aaaaaagtag
     8281 gattttgtta ttaaatattg aatttattat agtaaaaaag aagattggag ttttaaagtg
     8341 aataaaaaaa agattgttat tatagggatt atttattcat ttttagtagt attttcactt
     8401 acaaatatgt atgtaaatat ggagtataat ctaaatgtat ttgaatatat taagaagtca
     8461 cttccattta cagaagaaga aaaaaagtgg ttagaaaaac acaagaattt gatttacagc
     8521 tctgaccaaa gttcacctcc tttgagatat aaaggtaagg aagatggaca gtataaggga
     8581 attattgttg atttaataaa ttctctgtca attcaaattg gtagagattt ttattttaaa
     8641 ccaaataatt ggtggaaaga atctttcgta aattcaatag atgatagtat aaagtttttt
     8701 gacttgattc catcaaaaga aagggcaaat aaatttatat ttactgaccc aatatacact
     8761 ttgagtgcaa atatattgaa agataaaaag tcccaagata taaatagtta catggattta
     8821 aaggggaaaa cagtagcaat tccagaaggt gattattcta taaatttttt aaagcaaaaa
     8881 attcaagata taaacatttt gttgactcca gatataaaga ctggagtcaa ccatttaatg
     8941 tctggaaaag tagacgcagt tgttggtgat gaaccagtat tgcgatacta tataaataat
     9001 tatggacttt caaataaata cagtgtttta agtaatccta tatatactaa aaaagcagtt
     9061 cttgctgtac ctaaacaata tgaagagctg gttagtattt taaataaagg catttttaaa
     9121 cttcagaaaa atggagtgta taaagattta aagaaaaaat ggtattctac gtataatgaa
     9181 gttgatgata tattgtatga gcgaggaatt gtgcctagta tttatctttt tataggtata
     9241 attttaatat caatttatgt tttttatagc tatacatatt tgttaaagat agaaatcaaa
     9301 aggaaaacag aacaggtaat agaaaataaa aaaactttag aggcaacttt taatagtatt
     9361 acagatataa taatgcttgt agatgaaaat aacaatatag tagaatcgaa caaagtacta
     9421 tatgacttta tgggtgaaat gagttataag atagcagatt tgattagcat gataaaaggt
     9481 gttattgaaa ataccttctc tgaaaatact aataaaacta gtgaaataga aatacacaat
     9541 aaaattttaa agataaacac ttttcctgta gagtataaaa aaaataatac tgagtatata
     9601 gtagttctta ttaaagatat aactaatgat aaaatagtag aggcgaaatt acttagagaa
     9661 aacaaaatga tatctatagg acaattagct tctggggtag cacatgagat aagaaatcct
     9721 ttgggtataa taagaaataa ttgctatctc ttaaaagata acgttacaat ggaagaagta
     9781 aatgattgtg ttaaatcaat agaaagtaat gtagataggg caagtaatat aataaccaac
     9841 ttgttaaatt tcgcaagaat atcagatgat aatttagaac atataaatat aagaaatttt
     9901 attgaaaata tagtgaaact tcaatataaa atgttacagt taaagaatgt tgaaataaaa
     9961 attgactgtg aacataattt agtatgctat ataaatggag aatcgttaaa acatgtattt
    10021 ataaatttaa tttctaattc aatagatgca atacatcaag atggaaaaat tattatatac
    10081 tgttatgaaa aaaattattg tttatttata gattttaaag ataatggtga aggaataaaa
    10141 gaagatgccc taaaggacat atttaatccc ttctatacaa caaaaccaat tggtgaggga
    10201 actggtttag gtttatacat tacttataat gagattaaaa agaataatgg agatataagt
    10261 gttgaaagta aattgggggt tggaacttgt tttcatataa aaattccatt aaataaagag
    10321 gtgactatat aatgaaaata ctattagttg atgatgagct agaatatgga gtggtaatga
    10381 aaaaaattct acaaaagaag ggctatcttg tagatatagc actaagtggt gaagaagcta
    10441 taaatataat taaaaaagat aaaaattatg atttggtttt gtctgatgtt atgatgaaaa
    10501 atatggatgg agtacagcta ttagatagaa ttaaatctat taatagagat atagaggtta
    10561 tattagttac aggatatgga agtattgaaa atgcagttga tgctatgaaa agaggagctt
    10621 tatcttattt tataaaaagt aatcccattg aaaatttatt agaagaagtt gaaaaggtaa
    10681 aggcaagtaa aatatctgtt tctgtacaaa aaaataatct ggaatttact ttggaatcta
    10741 aaaatagaga ttttaataat atcataaaaa tagcaaaaaa agctgcttgt aaagatgtta
    10801 atatattaat cttgggggaa tctggtgtag gaaaagatat attagctaga tatatacata
    10861 gcataagtcc aagaaagaat gagatatttg tacctgtaaa ttgttgttct ttttcagaaa
    10921 atctattgga gtctgagttg tttggtcatg aaaaaggttc ttttacagga gcagtagata
    10981 gtagaaaagg tagatttgaa ctttcgaata aaggaactct atttttggat gaaataggag
    11041 atatacctct aaatgttcag gtaaaacttt tgaggacact tgaggacaaa tctatagaga
    11101 ggataggaag taataaatct attaaagttg actttaggtt aatttgtgct atgaataaag
    11161 aaccaaaagt ggaaatatca aatggaaata taagagaaga ttttttttat agaataagta
    11221 caataacaat aactatacca ccgctaagaa agagaagaga agacttaact actcttatag
    11281 aatttttctt aaataagtac caaattgaac atgataaaaa gatacactcg attgataagg
    11341 aagtaaagga ttttttatta aattacaatt atccaggaaa tataagagaa ttaaaaaata
    11401 taataaatag acttgtagtt ttaagtgaag aaggcaattt atcaaaagac aatttaaatt
    11461 taatatcaaa taatgtatac atagatgata aaataagtat tagaccttta agagaaataa
    11521 gaaaagagtt tgaatgtgag tatattgaaa aagttttatc tttgtgtgga aataatattt
    11581 caaatacagc taaaaaattg gagattagta gaagacagtt aaccaataaa atatcagagt
    11641 ataatattaa gtgagaaaaa aacttctcat taagtgagaa aaaaatttct caaactgtat
    11701 taaaagataa acagaaaaaa tctgtttatc tttttttatt ataattttaa aaattaatat
    11761 ttacaataat tattgctaaa ttcaatattg gtgtaaatta aaaatgaaaa tttctatgac
    11821 attaatacat agaatatata ttttaaataa ttggcataga aaatgcttta tatattaata
    11881 aacgtaataa atacttttaa ttgcgattaa atatattaag ggggattttc atatgaagct
    11941 agagctaggg aatatattta taaaaaatgt tgaatttgga gaaaagacag aagtaaaaga
    12001 tggagtacta tatattagta gcgaagaaat agaaaagata gtattagaag atgaaaggat
    12061 tgtaagtgta aatgttgaac ttgcaagacc tggcgaatca ataagaatag ctccagttaa
    12121 agatgtaata gagcctagag ttaaaattgg agatgaaagc aaaatatttc ctggaattat
    12181 aaataaagtg aagactgtag gaagtggaag aacccatgta cttttaggag cttgtgttgt
    12241 aacttgtgga aatatagttg gatttcaaga aggcgtaatt gatatgagtg gtcctactgc
    12301 taaatataca cctttttcaa aaacaaataa tatatgtatt gttataaaag caaaggatgg
    12361 tatagatact catgattatg aagaagcagc tagaattgca ggattaaaaa taggtgcata
    12421 tgtaggtgag gcaggaagag aagttgagcc agatgaagtc attgtatatg agacaaagcc
    12481 attattaaaa caagtaaaag aatatccaga cctgccaaca gtagcatatg ttcacatgtt
    12541 acaatcacaa ggacttttac atgacactta ttactatggg gtggatgcta aacagatagt
    12601 gcctacattt atgtatccaa ctgaaataat ggatggagct ataatatctg gaaactgtgt
    12661 agcaccatgt gataaggtta caacattcca tcatttaaat aatccagtta tacatgactt
    12721 atataaaaga catggaaaag atttaaactt tataggagtt attttgacta atgagaacgt
    12781 attcttagtc gataaagaga gaagctctga tatggtagct aaattaatag aatttttagg
    12841 agttgatgga gttctagtga cagaagaagg ttatgggaat ccagatactg acctaatgat
    12901 gaattgtaga aaatgtagtg aagttggagc aaatgtagtt ttgataacgg atgaatttcc
    12961 tggaaaagat ggcaagagtc aatctatagc agacgctact aaggaagcag atgcagttgt
    13021 ttcttgtggt caaggaaatc tagtggttca tttcccagca atggaaaaaa ttataggaac
    13081 tttagattat gttgaaatga tgataggtgg gtataaagga tgcttaaatg aagacggaag
    13141 catggatgca gagctacaaa ttataatagc atcaactata gcaaatggct ataatcattt
    13201 gacagcaaga tattattaaa taagtatttg aatataaagt tctgttgata taatcattgg
    13261 tctaattgat gtaacaacta taaagtgatt tggaggatta agagatgagt aaaatcagag
    13321 tggttcatta tataaacaat ttctttgctg gtataggtgg agaggaaaaa gcagatattc
    13381 cgccagaaaa aagggctggt gtagtaggac ctggaatagc atttcagagt caatttaatg
    13441 atgatgcaga gataatctca actgtaattt gcggagatac gtattttggt gaaaatattg
    13501 agagtgcaac tcaagaactt ttaaaaatga taaaagaaga aagccctgat ttatttattg
    13561 caggcccagc atttaatgca ggtagatatg gagtagcttg tgggactatt tgtaaggcag
    13621 ttgaagaaga gttaaatatt cctgtaatta caggcatgta taaagaaaat ccaggtgtag
    13681 atatgtttaa attagatttg catatagtgt ctacaggaaa ttcagcagca agtcttagaa
    13741 aggtagttcc aataatgaca aaactaggtc ttaaattggt tagaggtgag gaaataggac
    13801 ctcctgaaga ggaaggatat ataatgagag gaataagaaa aaatttcttc catgaactta
    13861 gagggtctga aagagcaatt gatatgttgg ttaaaaagat gaaaggggaa agctttgaaa
    13921 ctgagtatcc aatgcctgaa tttgatagag ttacacctat gaaacctgtt aaagatttat
    13981 ctaagataaa acttgcccta gtaacttctg gagggatagt tccaattgat aatccagaca
    14041 aaattgaatc ttcaagtgct actaaatatg gaatttacga tttaacagat atggattcta
    14101 tgtcaaataa agaatttaca actatacatg gggggtatga cagagcatat gtccttgaaa
    14161 atccaaattt agttgtacca ctagatgtag ttagagagct tgaaaaagaa ggtgtaattg
    14221 gagaattagt agattatttt ataactacta caggaacagg aacgagtgtt ggcaattcta
    14281 agagatttgg agaagagttt tctaaaaaat tgttagaaga tgatgtagat gctgtaattt
    14341 taacttctac atgaggtact tgtactcgtt gtggagcaac gatggtaaaa gagattgaga
    14401 gagctggtat agcagttgtt catatatgta cagtagtacc aatatcactt acaataggag
    14461 ctaatagaat tgttccagca gtagggatac catatccact tggaaatcct atgttaggag
    14521 aagaggaaag taaaaaaatt agaaagaata tagttttaaa agctttaaat gcactaacag
    14581 aagatataga agaacaaaca gtatttgaat aataaaaata caacacaaca ctgaaataaa
    14641 aaaagatatc aaaaaataat tttttaaaat tattttacga tatctttttt ttattaggta
    14701 aattcgaaat ttgcattttt taaaattaaa tttataaaag tgataaatta gtttattata
    14761 atattgatac acaaattcaa attagatata ctatgaaaag cgagattatt acattttgga
    14821 acaaatattc aacatattag atcatattaa ttgaacagaa aaaattaact ttatataata
    14881 attagaataa tgataagaaa gaaggtgtat atattgattt caattgccat ttgtgatgat
    14941 gaatcctata tgctaaatca tttaaaggaa aatatagaat tatacatgaa gcagaagaat
    15001 ttattatata atatagagct ttttaataaa gtagaagatt tactatgcaa tcatgaaaag
    15061 tttaatattg tatttttaga tatacagatg gaagagatta acggaatgca ggcagctaga
    15121 aaattaaggt catatggtaa tgagtgcttt ataattttcg ttacagtttt aaatgaattt
    15181 gtatttgatg cttttgaagt agatgctata aattatctga taaaacctct atctaatgag
    15241 aaactatata aaactttgga taaaatagtt acaaaacttg atgataatga aagtaattat
    15301 atcacaatac aaaaaggtta ttcatattgg aaattaaaac ttgctgatat tttatattgt
    15361 gaagttataa aaagaaagat ttatgttcat ttaaagaaag agactgtaga ttattatgag
    15421 actattgaaa atttagagag aagtttacca acaaattttt ttaggtgtca tcgtagttat
    15481 ataatcaatt tacaatatgt atatggatat gaaaatggta atgcagttat ggaaagtgga
    15541 gatagaatac ctgtttctag actacgtcaa caaatatttt caaaagttat gcttgagttc
    15601 atgaaaaata ggaggatata agatgattaa tttattttct tccgatttat ttttaaagta
    15661 cagtttttta ttttctttta ttgtatatag aattttaatg gtaatagtgc aatactattt
    15721 tctaatcagt tttacaaatg ttaattcaaa attttggtgt tttattttat attcgataat
    15781 ttcaattttt ttaatcatta taaatacata ttttaattta tataatttat tttcttcaca
    15841 gattctattt tttcttatga cttttttatt tgtaaagtac ataataaaac aatctactgt
    15901 tttatctata gtatcaactt tgttagtata tttaattgaa caattagtat atggatttac
    15961 agctccatta aattacttga tatttactag tgatataaat acagatattt ataaatttga
    16021 tataaatatg ggactatctt ctttaattac tattataata gctggattta tatattggta
    16081 tagttctaaa aagtttaata ttaaggtcat gaactttgat aaatatatag caattttgat
    16141 gattccattg ttgcttataa tattatttat gcaatcattt gaatatagtt caaatataaa
    16201 tatagataca agtcttggga ttgtaaagct gctattaaat acttctataa ctgaagaaat
    16261 tcaagctttt cttttttcta taattggaac tatatgtgta tttttttctc tatttacctt
    16321 taagaaacta attcaagctc tcgaagatga caaggagagg gcaattatga atcaacagat
    16381 tcatgctcaa aaaaactata ttgaagaagc gaaatcacga ttatcacaaa ctatatcctt
    16441 tagacatgat tttaataatc atttagctat tgtcaatgga ttgttgaaaa aagaccaaat
    16501 tttaaaagca caagattatt taaataagct tgaaaaagta acaagtgacc tatcattttc
    16561 ttgtaataca cagaatattg ttattgatgc tcttttcaac aataaattaa gtatagcaaa
    16621 acaattaggc atagaggtag attgtgaagt aattataccc caaagcacta acatgaacga
    16681 ttttgaccta tgtatagtgt ttgctaatgc tattgacaat gcaattaaag cttgtagagt
    16741 tgtagataaa caaaataggt atttaaagct ttccactaag ttagagggtg gattttttat
    16801 gatagaaata aaaaatagct ataatccaat aaataattat acaagtggct caggtatagg
    16861 tcttttaaat ataaaagaaa ttgctaaaaa atatcaaggg gctataagta tagataagac
    16921 atcagattat tttcaaataa atgtattgct ggttatttca ttacattgcg ctagtatttg
    16981 ataacaattt cattgaaaat agtatttgta agctatatta tgtacttgaa tagagaaagt
    17041 ttgatatata gaaatgagga ggttactaaa atgaaagttg gaaatataaa tggtcaagca
    17101 ccaattacaa atggtttaga tagttgtcaa agtgaggtac aaggcttaga acaaaagaaa
    17161 aaatcattac aggatgaaat agagaaagta agaagtgata aaagtattga tggtgaaaca
    17221 gccaaattaa aaatagaagc tttaaaaaaa gaaatggaag agattgaaaa taaaattcaa
    17281 gagttaaaag gaaataaagc aaaaaaaaca aataaagaag aaaataatgt ttcagaagta
    17341 aataataatc tattagagag aaaaaaagaa ccttctaata atgaaaatgt aaaacaatta
    17401 tatgatgttt ttgaaagaag caatgtagac gaacaatggg ataatactta tcgtgttctc
    17461 caagatgata aaaacttaaa agtaaaattt aatagaccta tatagtttat ttataaaaat
    17521 agttaatatt ttaattatca ccacttttta gaagaataca cactttattt taaagaccca
    17581 catatttatt tacagttagc acatttatat gtggttttat aactattatt tacaagtcta
    17641 tattgataac ttttacatag tatataatgt ttaaatactt attcaaattt atctatacat
    17701 aaacaaaaaa agagatttta aaatctcttt ttagattgtt gacttatggc tttttgattt
    17761 aataaaatca agaagccgtt tgaattttat ctgttggctg atacccttct gatattgaaa
    17821 caccattttt gtttccaaaa tcgtttaaaa ttaagaactt attatgaatg actatttcat
    17881 tatgaacaat aagcagataa catgaatctt caatcaatgt tttaacagta gcattaaatg
    17941 cttgcttata cagttctatc gtttgtttga actgtccatt aaagtaaata tgagtcaata
    18001 acataactat atctacacaa attaatataa attttttata ctgtacatta tctaactgtt
    18061 gattatctgt attacaacat gattgaattt aaaaagccat caacacatag aatgttgatg
    18121 gcctgaaaat agatttaaaa tctctttttt attatatatt aattattttt taaatttata
    18181 ttttttgcat cagattttct aatagctaag tcaaaccctc taaatctaat cactataggg
    18241 tcattaagag gagctatctt tttcacttca acttcagtgc catctattag tcctaaggct
    18301 agaagtctct tcataagttt ttcatttcca gctatattgt ctataattcc cttttgtcca
    18361 agttttaagt tgtaaacagt cattattaac acctcctaat gaaaatcatt atcaaacttt
    18421 atatttataa tatataacaa aaagagcaaa ttgtcaatat ataacaaaaa ataaacatac
    18481 taagttagta tgtttataaa aaatagtata catgggatac taatagcatc tagcaaaaaa
    18541 ccacttacta atggtacaac taaaaaggct tttggagaat caccatattt ttgtgtcaaa
    18601 gaactcatat ttgccagagc gttcggagta gctcctattc catgtccaat caaaccactt
    18661 attatgatgg cagaatcaaa atcttttcca agtactctaa agcaaataaa tattgaaaat
    18721 aggattataa agattacttg aaaagttact attaagagaa taggaggtaa taatgtagat
    18781 aattcaaata aatctatatt cataagtgat aaagttaaaa aaattcccaa tgaaagttct
    18841 tttaaaaaat ctataagttt aaaatttaat tctagtatat ttatcttatc atttaaattt
    18901 ctaaaaataa cagccgaaaa catacaagtt acaacagagg gtaatagtat attaaacgtt
    18961 atatagaagc atctacttat aatttctcct gtatttatac aaataaatat gagaagaacc
    19021 tgttccaaaa atacagatgg tgttattgtt tcggagaagt tattattttt tatcctattc
    19081 ttatttctaa aaaatttact tccaaatctc tttagatttc tattatatct aggaatcgac
    19141 aagtctatat ttgatgatgg ttttaattta tatttattta ttagaaattt agctacagga
    19201 catcccaata taccacccat aataagtcct attgttgcag cagataatcc aaccccaact
    19261 gctccttcta taccgagatt ttctattgta agtccaaatg cagcagaata accatgacca
    19321 ccttccatag atacatttcc acacataagc cctaaaagag gttcaagttt tataatcttt
    19381 gatattgtaa tagctaatat attttgacaa aatgccaata ctccacacaa aatccaatat
    19441 ctaaataata cactaccacc tttctttata agatttatgc ttatttcaag tcctatagtt
    19501 gtaaaaaaga aggttatgaa atttggcatt aaatttccac ttatagatat atctgctata
    19561 ttaaaatatt taaaaaataa atttagaaaa caaaataata gacctcctat tactggtgca
    19621 ggtatacaga aattatttaa aaagttaact ttattcttca ataaattacc aattaaaaag
    19681 aagaatatag atagtgtcaa ggtttgcact atatcaaaac ttaaggtaat caaaataagt
    19741 cctcctttgt aattcaaagt tttaattata taacttaaat tcttatgtat tgaaatttta
    19801 ttatcaaatg tatattaata aatgtatatt aaaaagaatc agtagatata attagatagt
    19861 cataaattaa attaaaatat tttaatgaga tatgactttt ttagaattaa aaaccgtagt
    19921 atattgatat aatagaaata agacttaaaa atctgttgat agtattattt ataagtacag
    19981 taggaggata aaatgtttga aaatttacct aagatagatt tacattgcca cttagatgga
    20041 agtgttagag tagaaaccat gcttgatata gctattaaag agaaaataga tttaccttca
    20101 aataatatgg atgaaataaa aaaattagca aaggtttctt ttaattgtac ttcactagat
    20161 gaatatttag aaaaatttga tttaccctta aaagtaatgc aatctaagga aaatttaaaa
    20221 agaattactt ttgaactttt ggaagatgca agtagagaaa atgtaaaata tattgaaatt
    20281 agatttgcac cattacttca cacccaaaaa ggtatgagtg ttaaaaatat aattgagggt
    20341 ataattgaag gaattagaga agctgaaagt atttatgata taaaaggcaa tttaatatta
    20401 ggttgtatga gaacaatgac ctcaaaagag gcattattag taattgaaga agggaaatca
    20461 tttgtaaata aaggtgttgt agcagtagac ttgtgtggtc cagagaaaga gggattttgt
    20521 aaggaatata aagatgtttt taaattagca agagaatatg gatataaagt tacaatacat
    20581 gcaggagaag ctgcaagtgg agaaaatgta ttggatgcta taaatatttt aaaggcggat
    20641 aggattggtc atggggtaaa aattaaagac cataaaaagg cgtataattt agttaaagat
    20701 aaaaaaatat tgcttgaatt atgtccaact agtaatgtac aaactaagac agtagattct
    20761 tatgaagcac atccatttta tactttttat aaagataatt tacatgtaag tataaatact
    20821 gataatagaa ctgtatcaga tataaattta agttcagaac taaatgttat atttgatact
    20881 tttaaactag gattagaaga ctataaaata atttatagaa atgcagtaga agctagtttt
    20941 gcagataaag aaactaaaga gtatttgaat agtttaattt aatagataaa aatatttaaa
    21001 ctttaaatta agctattaaa ttgataaaaa tacattgtat taggagaaaa aatgtgaaag
    21061 attatgaaga tgttgtttat attaaactag tcaaaaaaga acttgaagaa tggaagaaaa
    21121 atatattaaa gaaaccttct atatttgaca aagcatcaaa gggtatacag aataaattta
    21181 atggagtatt gccagataaa tatcatgaaa taattacttc ttctataaaa gtaatgacaa
    21241 aaaccgtact gtttggatat aaatatgcta caaagccacc acttagaaat atgtcattag
    21301 aagaaagaga aaaattagtt ttagaaaaag ctaaaactta caagactaca gcaatgattg
    21361 aaggggcagg aacaggggca ggaggaatcc tcttaggttt atctgatttt cctttgcttt
    21421 taggtattaa agtgaaattt ttatatgatg tagcttcaat atatggatat gatgttaaag
    21481 attatagaga aaggatttat atattaaata tattacagtt ggctttttct agtcaacagc
    21541 atataaacaa aacttttaaa ttgatgaata actgggatga atatgtaaat agtctaccag
    21601 aagacatcaa tgattttgat tggagaacat ttcaacaaga gtatagggat tatttagatt
    21661 tagctaagtt tttacaacta atgcctggaa taggagcatt tgtaggattt tatgtgaatg
    21721 gaaaattaat tgataaatta tgtgaaactg ctgtgtctgc ttatagattg aggattcgag
    21781 agcttaagtt ataagaaaaa ttataacata aaaaattagt tatacaatat atctatatgt
    21841 atctaatttt gcattgataa aaacaattat ggataaaagg taaagcatga tagaatctaa
    21901 tgtagaggtt tgtattttaa tggaaaaatt tagtttttat tgcttaagat acaaattgaa
    21961 ttacgaagag attgaattat gaagagaagt aattgggagg aatattttca tgacaaattt
    22021 gccaaaacaa tttgatagct tcaatgaagc tagacaaaaa ggatttataa atgcaaagga
    22081 acttaaggaa agtgggaaaa agatggttgg agttttctgt acatttactc cagttgaaat
    22141 tccaatggca gctggagcaa ctgtagtagg tgtatgcggc gttagtgaag agccaatacc
    22201 tgatgcagaa agggtgcttc caagaaatct ttgtccttta attaaatcaa gctatggaca
    22261 tgcaataaca gatacctgtc cttatttcta tttttctgat ttgttgatag gagaaaccac
    22321 ttgtgatggt aagaaaaaaa tgtatgaaga acttgcaaaa gttaagccaa catatgtaat
    22381 gcatttgcca aatacttcaa aaggagaatt tgcctataaa ctttggaaag atgaaatgat
    22441 aagattaaaa gaagaggttg agaaatcttt aggtgtaact ataactgaag aagatataag
    22501 aactgctata aaagataaaa atgaagaaag agaactttta aaagagtttt atgcacttgg
    22561 taaattacaa ccatctgcac ttacaggcct tgagttacat aatgttttat atcaagcagg
    22621 ttttaaattt gaccgtgcag aacttaaaca ttctttaaga aaagttatag atgatatgaa
    22681 agaaagatat gaaaaaggtg aatgtcctgt tcaaaaagat aagccaagaa tattgataac
    22741 aggttctcct attggtggaa taagcgaaaa aatagttaaa actttagaag atgcaggggc
    22801 atcagtcgtt gcatatgaac tttgtggagc tattagatca aacgatttat tggttgatga
    22861 agaaatagaa gatgtatatg atgctttaac acaaaaatat ataaatatag gttgttcttg
    22921 tatgatgaat aatgacaatc gtattgaatt attagataga ataatagatg aatataatgt
    22981 agatgctgta atagatgtag ttttacaagc atgtcataca tttaatatag aaagttatag
    23041 aataagagaa tttgttacaa aagaaaaaaa taagccattt atgtctcttg aaactgatta
    23101 ttcaaaatca gatactgaac aattaagaac tagatttgaa gcgtttgtag agatgttgta
    23161 ggaataaata aaagtaggag gaactatgtt tagtatagga gttgactcag ggtcagtggc
    23221 aacaaagggt gtgctatttg atggtgaaaa aattattaag aaaataatta taccaactgg
    23281 atggagccct aaaagtacat ctaaacaggt ctatgagttg ctaagtagtg aaattgacaa
    23341 aaaagatata aaaaaggtgg taggtacagg ttatggaagg ggagtaatgg attttgctga
    23401 taagaaagta acagaaataa cttgtcatac tagaggtatt tactttttaa acaagaacat
    23461 aaggactatt ttagatgtag gtggtcaaga tagtaaagtt ataaatttag atagagatgg
    23521 aaatgtattt aactttataa tgaatgataa gtgtgctgca ggaactggtc gatttttaga
    23581 gattacttct aaccttttag gaagcgatat tgaaagtata gatacattag ctaaaggata
    23641 tgaaccagtt aatatatcta gtatgtgtac agtttttgct gagtctgaaa ttgtaagtct
    23701 tctagctcaa aacatttcta ctggagaggt agcagcaggg atacttaaat ctattgcaaa
    23761 taaatccacc tcaatgttag caagaggtga ggtaatagat gaagttgcat ttactggagg
    23821 gcttgcaaaa agtaaagaac tagtaaaaat gatagaagaa atactgggta aaaaaatttt
    23881 tattgcagaa gatactcaaa taataggagc tttaggagct gctgtaatag gatttagata
    23941 aaaacatata aaaagaaaat gagaagctga atttattata aataaattca gttttttatt
    24001 ttattttatt tatttataaa ggaaaacttt ggtataattg atttaaatga ttgtatattt
    24061 gtaaatactt gatatttagt catatataac attataattt taaaaattag ctcaaaataa
    24121 gggggagaaa gcgtgaaaaa atttacttca aaaaaagtaa caaggtttgt tgcgctgttt
    24181 ttaatatcta ttttagtaat gtcaacaatt cctgtatcag ctgacaatag caatacattg
    24241 aatcagataa aaaaagcaga atacagtgag acgtataaac aatatctaaa tgatgctaaa
    24301 aatggatgta cagaaaaata taatgggatt ataccaaatc catatcagtt ggaaggtact
    24361 caaatccaaa gtaaaggaag aacagctcca acatcttatg accctagaaa attaggtctt
    24421 atgacatcaa taaaaaatca agaggattta ggaatctgtt gggattttgc tgcaatggca
    24481 accttagaaa gtttcttaaa gttaaataat tatggagact atgatttatc agaagaacac
    24541 ttaagatggt gggcttcaga tggtgaatat ggatggtctg taaatgatat gaatggtgct
    24601 ttaaattatg aagctatggg atatttaaca tcttggtcag gtcctaaatt agaaaaagat
    24661 atcccataca atggtagagt atctaaagca caaggagcaa aaaaaccaac taatatgaat
    24721 acagcaccta ctgtttttaa tgtgacagat gctgtgtgtg taagcaatga cataaattct
    24781 acaaaaaatg ctatattaca gtatggagct gtaacatctg gttattatga agatattaaa
    24841 tatcaaagtg atgaccaaaa ttcatattat tgtccaacaa aaagttttaa tacaaatcat
    24901 gctatttcaa ttgtaggttg ggatgataac tattctaaag ataattttaa tgcaaatatt
    24961 agaccatcaa aaaatggtgc ttggttaata aaaaatagct ggggagatta taattctgag
    25021 ggtggatatt tctggatatc ttatgaagac aagacactta tgtctgatat agataatttt
    25081 tcaatcaaag gtggtaaaaa accaaatgat gatgagaaga tgtatcaaca tgactatgca
    25141 agtattgtac ctttaatttc aaaaaagata acagctgcaa atgtatttga tttcaataga
    25201 ggcgatgaaa ctctaaaatc tgtaatgttc ttaactgaaa gtataggagc taagtatgaa
    25261 gtatattatg ctccagtagt aaatggtata cctcaagaaa acaatatgaa aaaattaaaa
    25321 gaaggtactg cccaatattc aggatacata acagttccaa ttgattcttt tgatatacca
    25381 gaaggaaagg gtgcaattgt agtcagtata gaggggaaaa atggagagtc aactataggt
    25441 tctgagtcaa atgtaccagg atatgataca tttaaagcaa aagctaattt aggtgaaagt
    25501 tatatcatag ataatactgg aaaattcttt gatataaata gagatagtaa cttctatccg
    25561 tgtaatttta ctataaaagc tgttacagaa aagtcttctg gtgagagtat cccaaatgag
    25621 tctttaattg gtagtgatag atatgaaact gctatcaaag ttagtcaaaa tggtttcaat
    25681 tcttcagaaa atgtagtttt agtaaatggc agttcaatag tagatgcatt ggcagcaact
    25741 ccttttacat ctgctataaa ttcaccaata ttattgacac aaaaagaagc tttaaattca
    25801 aaaactaaag ctgagataca gagattaggt gctaagaaag tatacctaat aggtggagaa
    25861 aattctataa gtaaagaaat tgaacaacaa ttaaaaagct taaatatatc gatagagaga
    25921 atatcaggaa gtgatagata caagacaagt ttattattag ctcaaaagtt aaatggtata
    25981 aaaaatgtat ctcaaatagc agttgtaaat ggagtgaaag gattagctga tgcaattagt
    26041 gtaggcgctg cagcagcaga aaataacata ccaatcatac ttgcaaatga aaagagcgaa
    26101 ttgcaaggag ctgatgaatt tctaaattca ttaaatatag agaaatctta tattattgga
    26161 ggaacagcat ccctatcaaa caatctagaa agtaagttaa aaaatccaac tagattatct
    26221 ggtagtagta gagacgaaac taattcaaag ataatagata atttttataa aaaagatact
    26281 ttaaaaaatg catttgtagt taaaaatgga atcaagaatc aaaatgattt aatagatgga
    26341 ttggcagttg gtcctttagg agcaaaaact gggtcaccag taattttagt tggtgataaa
    26401 ttagctgata gccaaaaaga agttcttaaa aataagactt tagaaaaagt aactcaagtt
    26461 ggtggaggag caaataaaaa tgcatttaaa gagttagtaa aattaaaaag tgctaaatag
    26521 agtacttaag tattaacata tattagtgtg tattagtaac ttatcttaat aaaagctgaa
    26581 aataattact tcaaattatt gataaataag ataatcaatg attgtaaagt tttgttttca
    26641 gctttaaatt tatgtagtat aagtttaaaa acataaaaaa gggttacttt atatagaaat
    26701 atagaaaatc ttacatttta tatataaata acccatattt aattaacttt ttatagtgtt
    26761 ctaatagata ttattgaact taatggtaaa tataatgtgt aagtttcatt taaagttgga
    26821 ttagattcat ctatatatct tgagcaaagt gtaattgata agctatctgc ttctataatt
    26881 tcaccatata gaggacaact gctaaagtaa gaatgtactt caacatattt atttaagttt
    26941 tcttgaacat aatcgtaaaa acggtttttt gtagtagtag ccataaaatc aactccttta
    27001 ttttttatta aagttgaaac ttttaaaaag ataaatatga ttacttctat tagaaactaa
    27061 gttaaaaaat aagcaaatag atatgaaaat tagaataata tattatttat atcttaatta
    27121 taacactaga taataaaaaa tgctatataa aattcagaat tttcgaaagt ttttaagctt
    27181 atttttaaat atactaataa tactattgac attagataga aaaagtatta tattgactat
    27241 ataaattatt ttagtcaaac tggagggaaa agatgcctaa atcatattct gataaagaaa
    27301 gagagtatat aataaaaaga cttaaagaag aagcaagatt gtgtatggag caatatggta
    27361 ttagaaaaac tactgttgat gagcttgtaa aacgggtaaa aataccaaaa ggaacttttt
    27421 atctattttt tcaatcaaaa gaattactct tttttgaggt attaagagat atacatgact
    27481 ctatacaaaa agaaatctta tatgagataa atagagtaga tgaaagtatt acatgtgaac
    27541 aattgacaga tatatttatg aaattctata ggatggttga tagtacttca attttaaatc
    27601 tcatgataaa tggagaattt gagatattgg tgagaaagtt accagattct ataattgaag
    27661 aatactttag acatgatgac tttgaaattg gagagattat atcttgcata ccaaatgcaa
    27721 aaaataaaga catagaaagc tttagtggag catttagagc agtttttctt accatgctat
    27781 ataagcgcga ggttggaagt aattgttttg aagatgcttt aagattaatg ataaacggat
    27841 tagttataca acttatggaa tagaatttaa attttgtttg ctaataactt ttattaaaaa
    27901 ttattaacaa acaaaaaaat tatattttat tgaccatata gtcaaaatag tcaaaaattt
    27961 gaaagggtga tattgaatga ttaaagttga tgatttatca tttagttata cagatagaga
    28021 ttttttacaa aatattaact ttgaagtagg aaaaggggaa atactaggat ttttaggacc
    28081 atcaggtgca ggaaaatcta cattacaaaa gattctaatt ggaatgataa ctaattatgg
    28141 aggaagtgtc attgtaaatg gagtagagag taaaagacac tcaaataaat tttatgaaaa
    28201 tataggagtt gattttgaat ttcctagttt atatgaaaag ttgactgcaa tagaaaattt
    28261 aaaatatttt gggtctctat attctaaaaa actactatct attgatgagt tattaaaatc
    28321 agtaggacta gaaaatgaat caaataaaag ggtatctgag tattcaaaag gtatgaaatc
    28381 tcgattaaat tttataaaag ctttattaca taatccagat attttatttt tagatgaacc
    28441 aacaagtggt cttgacccat caaatagcaa ggttatgaaa gatataattt tatcagaaaa
    28501 atcgaaaggt aagactatta ttttaacaac tcataacatg ttagatgcaa cagagctttg
    28561 tgacagagta gcgttcattg taaatggtaa aatatctgct ttagatacac cacataatct
    28621 tattatgtca aaaggagcta ttaaagttag atatacttac tttgataatg gagaaaaaac
    28681 ttctgaatgt tttctgaaca atactgctaa tgataaaaat ttgaatatgc ttattgagaa
    28741 aaataaactt ttatcaatac atagtagtga accaacatta aatgatattt ttattgagat
    28801 aacagggagg aatttacaat gaggctaaaa aatcttattt taggagatat aaagtttcaa
    28861 tttaagtatg gtttttattt tttatatctt tttttaagta ttatatatat ttgtattatc
    28921 aatgtatttc caacttttat gagagaaaaa atagctataa ttatgattta ttctgaccca
    28981 gcagcaatgg gattgttttt tatgggagct attgtacttc ttgagaaaag tcaaagggtt
    29041 ttaaattcct tagctgtatc tccagtaaaa gtatctgagt atattttatc aaaggtaatt
    29101 tcattaggag taatatctag tattgtagct atgtttattg ctattacatt aaatttagat
    29161 aatattataa tatcaactat aggtaccttt ttttcttcta ttatattttc tttgcttgga
    29221 ttgataattg caagtaaagc atctagtttg aatcagttta ttgttttaag tattcctatt
    29281 gagattatat gctttattcc accaatactg aatgtacttc ttgacacaaa atcatatgca
    29341 aatttgtacc cttttaatat atgtatttct cttattagtg gagataaaaa ttttataatg
    29401 attaatattt taattttaat atcaattata ataataattt attttataac ttattatttt
    29461 atttgtagca gttggaaaaa ggtaggtgga gtaaaactat gataaagatt ataaatgcgt
    29521 ttaaacaaga gtttgaacaa attaagagag atgctatgct ttttatagta tgtgtttctc
    29581 caatattatg tggagtattt ataaaatttg gaataccatt aatacagaat atatcactta
    29641 acaagtttta ttatcaatta aatttagagc cgtatttctt gatgtttgat ttacttttag
    29701 cttttattac accttttatg ttcttttttg cttctacaat ggtcatattg ggagaaattg
    29761 atgacagcat ttcaagatat ttaatagtaa ctccgcttgg taaaactggt tatcttattt
    29821 cacgatttgg aataccaggt atcttagcat ttattattac tatgattcta cttatctttt
    29881 tttctctaac taaaatttct ctcttgttaa acttatcaat ttctttatta gttttattac
    29941 aaggagttat tatatcaata ttagtgattt ctttatcatc aaataaacta gaaggaatgg
    30001 taattacgaa attctcaggt gtttttatga tgggtatttt agcaccattt tttattttaa
    30061 ataaagcaca atatattctg ttcttcttac caactttttg gatatcgaag gcatttaagg
    30121 aagataatta tgtctatatg tttatttcaa ttgttatatc attaatatgg attttattat
    30181 tatttaaaaa gtttagtaaa aaaatagtta aataagaaaa tttaatatat aaatgtaagg
    30241 ttgacttgac agtaatgttg aaaaatgtta catttaagat gtaaagttaa ccttacatga
    30301 atggagcaaa tatgaaaaat aaaataaaga tattaagaga aaaattagga ttgacacaag
    30361 aacaactagg gagattagtt ggaacatcta gacaggctat aaatgctata gaaactggta
    30421 aaaatgaacc ttcaatatgg ttggcatatg atatttcaag aatttttaat gaaccaattg
    30481 aaagtgtatt tttatttgaa gaaagtgaaa gaaaatcaag agcacagata agtaggggag
    30541 aatattatgg ctataagaaa gataagaaca tttgatgatg aaattttaag aaaaaagagt
    30601 aagtatgtag aaaacgtaga taataagata agagaaatat taaatgacat ggcagagacc
    30661 atgtacaata ctccaaatgg aggaggatta gctgcatgcc aagtaggagt attaaagcga
    30721 ttagttgtta tagatttagg agaaggactt attaagcttg ttaatcctga aattattgaa
    30781 caagaagggg aacaaattgt tgttgaagga tgtttaagtt ttcctgaagt atggggtaaa
    30841 ttaaaaagac caaaaaaagt tacagtgcaa gctctaaacg aatacggtga gaaaatagaa
    30901 attaaaggtt caggttttat ggcaaaatgt ctttgtcatg agatagacca tttaaatggt
    30961 atagttttta cagataaaat tattgaacat gtaaaattgt aagatagatt ggttattgaa
    31021 tttataaaat attttatagt aaggagttaa attatgagat tatggcataa ggatttaatt
    31081 gatgtattac ctaaaaatca attagtaagt caatggagag agctacttgc tataaaaggt
    31141 tctatagata aaaaaggtac tccaaaccat ctattagtga ataaagtatt gaattatagt
    31201 atagatgaat ttaaatttta tacaaaaatt gtacatgatg aaatgttaaa aagaaattat
    31261 aaacctaatg aacttaaata tacaagtata ttaaaatgga aaaatagaaa ttttgcaaat
    31321 gatatatcta atgaacatag tttaaattta gaaaatttat atgatgattg gcataataaa
    31381 atgtatttaa agcaatgctt atataattta gaagaaaaag caacatgtgg aggaatacca
    31441 ataaatgaat ggaatatatt actttgtaaa tatagtaaag attatgaatt gtggtctgga
    31501 aatatcatgt tttaattact atagattaac attatagtat tattgtatat aaagaggtga
    31561 ttatttgtat aataaaataa aatatattcc aataaattgt gaaatagctt gtaataaatt
    31621 aaaaaggagt atgccatata aatgggattt aaatatttat cgtggatgtg agcatggatg
    31681 taaatattgt tatgctattt actctcataa gtacatcaac tccaataatt attttgaaga
    31741 gatttatgta aaaacaaata tagtagaaaa acttgagaga caacttaaaa gcagtaaatg
    31801 gaagaaagaa gtaatcaata taggaggagt tacagatagt tatcaaccaa tagaagctga
    31861 ctataaaatt atgccagaaa tattaaacct gctaataaaa tacaagacac cagctattat
    31921 ttctacaaag tcagatttaa ttttaagaga ttacgattta attgataagc tatctaggat
    31981 tacatatatc aatgtagcat ctacaattac cacagtaaat gaagatacac aaaggcttat
    32041 tgagccaaat ggtgtggatt caatgagacg atttaaaatg ttaaaagaat ttagaaaaac
    32101 taacgcatca gttggtctac atattatgcc aattatacca tatattacag atgattttga
    32161 taatataaat tcgctattta gacatgcaaa agaatgtaat gtacattatg ttttacctgg
    32221 gactttatac ttaaggggta taactagagg tgtttttttt gactttgtta aaaaagagtt
    32281 tcctgaatta tttgataaat tatcaatact atatagtgca ggttcactta atagggagta
    32341 taaaaatcaa ttgtataaaa tggttaatga acttagatat aagtattctc tatcaagcag
    32401 ttactctaaa ataatgaagg aaaagttaaa aaactcagga gatgtacaga tatctttttt
    32461 tgattagttt tatataaaaa aatttttttt actatgatga ttaaaattta ttaaaattaa
    32521 aatttattga caaatataaa atttaaatat ataattaatt cataaaataa aaatatgaaa
    32581 ggatgatgtt gttcggtgat atttgatatc ataaaatcgt tgatataagt attgctggaa
    32641 aagagtgaat aaaatcaaat ttaataagca aacaaagtaa agctatagtt ttattgttgt
    32701 gcttaaaaat atttggttct attttactct tatttaaact catctttttg aagttaaacc
    32761 acagagtaaa ctctgtggtt tttttatttt aaaaataaat tttaaggagt ggtatgtttt
    32821 gttaaacaaa ttatgtatgt atttagaaag accagagctt tataaacaaa gtgaaattaa
    32881 tttttgggat gatgagtata tttcaaagca attattaaaa gcacacttag acactaattt
    32941 tgaaggagca agtagaaatt ttaactttat cgaggattct gtaaattgga tagttacagt
    33001 tgcaaatcca gctaattatc ctaaattact tgatttaggt tgtggtccag gtttatatgc
    33061 agagaaattt gcacaaaaag gttataaggt aactggaatt gatttctcaa aacgttctat
    33121 taactatgca caaaatagaa ataaggagac taatttaaac ataaattact tgttccaaag
    33181 ttatttaaat atgaactata atgaggaatt tgatttggct actttaattt attgtgatta
    33241 tggagctttg tcaactgaaa atagaaggtt attaatggaa aaaatttatg atagtttaaa
    33301 acctggagga aaattaatat tagatgtatt tacaataaat aaatacaata attttgagga
    33361 aattaaatat tgggaaataa atgaagatgg aggattttgg agtaatgaaa aatatatgtg
    33421 tctacaagat aattgtaaat acaatgatta taatacatta gaacaaactc ttgtaataac
    33481 cgaaaaagat gaaaatgtat tttatgtttg gaatcactat ttttcaaaag aaagtttctt
    33541 attagaagtt gaaaatattg gatttaagtc tgttgagttt tttagtaatg ttaagggtga
    33601 agcatattct gacgatagta tgactatggg attagtttta caaaaataat aattttttta
    33661 aaatgaataa ataaaaactt gaaaccttta acaataaaat aacataataa aagcttacat
    33721 attgaaaaat ggaaactttt atgttatttt tagtacatta caaatttgct tatataaaaa
    33781 tcaatacttg aattattatt tttatgtgaa atttatctat agtatatttt tataaacaag
    33841 taatgttatt aaaattaagt atgtagttaa aagtgtatag caaaaaggct gttatattaa
    33901 tgttagaggt tcagggaaaa tatataaagc aaagtattta cagataatgt agattgcaca
    33961 gctataagtt agataataga attatgtaat caagaattta caacaaagta taagataagg
    34021 ataatgctaa attgccatac aggtgctaga tgtgtaaatg gatttaatta atactattga
    34081 taaagtgcaa caagcacata aaccaattga tgagattatt aaaactataa gagatatagt
    34141 tgacataatt aaaatattgg aacttgttta taattttaaa tcaaatcaat aatgattaag
    34201 attaaaataa tattaaggca tcaatgttat aagagtacaa tataaggagt actatatagt
    34261 actccttact tatacatatt aggcaatagg aaattttttc atagttaaat tttcaagtat
    34321 tttttaggaa actttataat tgagaattaa gggtatagta tgtgatgaac ttactgaatt
    34381 tataattag
//
LOCUS       DAEPHU010000043        33217 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 01A10CD0081
            SAMN05941466-rid12468953.denovo.043, whole genome shotgun sequence.
ACCESSION   DAEPHU010000043 DAEPHU010000000
VERSION     DAEPHU010000043.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941466
            Sequence Read Archive: SRR6291087
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 33217)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 33217)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068158.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 22:43:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,892
            CDSs (total)                      :: 3,805
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 87
            rRNAs                             :: 8, 1, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 55
            CDSs (without protein)            :: 55
            Pseudo Genes (ambiguous residues) :: 0 of 55
            Pseudo Genes (frameshifted)       :: 21 of 55
            Pseudo Genes (incomplete)         :: 28 of 55
            Pseudo Genes (internal stop)      :: 16 of 55
            Pseudo Genes (multiple problems)  :: 8 of 55
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..33217
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941466-rid12468953.denovo.043"
                     /strain="01A10CD0081"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            complement(149..991)
                     /locus_tag="KR231_002175"
     CDS             complement(149..991)
                     /locus_tag="KR231_002175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HBH0004542.1"
                     /translation="MINIGDFNKLTVKRKTEFGYFLDGQTNNTKDDILLHNRLIGKNE
                     INIGDEVNAFIFKDSDDRTAATLIPPLAKVGDVAHLKVVDNTDIGTFIDMGLPKDILV
                     PFKAKTYPLFRDEKYLFYIYLDKSKRIAATTDIDSYLLTDHTYNVGDIVTGVVYGFQT
                     NNSAMICVDNKYAGVILHNEYFTELKTGDVLENLHVIKIYEDGKLGLSPRGNRKDELD
                     TLENKILSYLEGSDGYMRFNDKSDPKDISILFNSSKKNFKRALGVLMKKGLIYQDEEG
                     TYLK"
     gene            1286..2020
                     /locus_tag="KR231_002176"
     CDS             1286..2020
                     /locus_tag="KR231_002176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBH0004543.1"
                     /translation="MKIVNKSSNIPLHTQLSSIIREMIETGELKEGDAIMPERELCNI
                     QNVSRMTVNKTIVGLVTEGLLYRVQGKGTFVAKQKKKYQFSNVKGFTDVMKEKGVNIK
                     TDILSFEMELPDDLVKRKLGISDNTTNIYKIVRLRYTDGEPFGLEIVYLSEEMCKGLT
                     KGILDNSSLYRVLNEKYGYKIQKAEQVMEPVILSDEESKLLETDEGALALKLHRNSYN
                     REGRPIEYTISIFRTDKYQYEIVLSE"
     gene            2030..3163
                     /gene="nagA"
                     /locus_tag="KR231_002177"
     CDS             2030..3163
                     /gene="nagA"
                     /locus_tag="KR231_002177"
                     /EC_number="3.5.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylglucosamine-6-phosphate deacetylase"
                     /protein_id="HBH0004544.1"
                     /translation="MKCLINGKIILKNQILENKVLVFDEKIIDIADSVPKDCEVIDAD
                     GKYISPGLIDIHIHGNMGKDTMDSTDESIETISKSIMRHGVTSFLPTTMTMDKEHVYD
                     ALEVIKKAQNRKLEGAQVLGAHLEGPFINENYKGAQNEKFIINSKYEFIKEYKDVIKV
                     ITYAPEKDIDFDFTREIKRCTDIVLSIGHSNANYDQAKEAINLGVTNVTHMFNAMTGL
                     NHRDPGVVGAALTTNVYSELIADTIHINKDLFQFILNNKGKERLILITDSIEAGGLED
                     GNYSLGGQKVIVKGNEARLENGALAGSVLSLNKMVFNFLNNTNLKVNEAINLASLNPA
                     TSLGINDKKGSLEIGKDADIAVFDENLDCKMTLCLGEVVYKNI"
     gene            3262..4011
                     /gene="nagB"
                     /locus_tag="KR231_002178"
     CDS             3262..4011
                     /gene="nagB"
                     /locus_tag="KR231_002178"
                     /EC_number="3.5.99.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012425552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosamine-6-phosphate deaminase"
                     /protein_id="HBH0004545.1"
                     /translation="MRVLVCKDYDGMSKKAAEMIAAQIVLKPNSILGLATGSTPVGMY
                     RDLVKKYNDNIVDFSDVMSFNLDEYYKLPISNDQSYDYFMKENLFNHVNIKPENTHLP
                     NGMADDIEKECMNYEASIDAAGGIDVQVLGIGRNAHIGFNEPDTKFAKRTHVVELTES
                     TIEANARFFKSREDVPKKAVSMGIGSILKSKKILLLASGEEKADAVYNTVYGDITPEV
                     PGSILQLHKDTIVIVDEAAASKLNPKDYKLV"
     gene            4163..4435
                     /locus_tag="KR231_002179"
     CDS             4163..4435
                     /locus_tag="KR231_002179"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0004546.1"
                     /translation="MLKIIMFSGILSSIIKLPIIGILPTGNIKKNTGISDSKKDGKQR
                     RSNLGISIYQLPSFLYSLINNSVPSNKPIPPEEIKLIKMYLLKSCI"
     gene            5095..5799
                     /locus_tag="KR231_002180"
     CDS             5095..5799
                     /locus_tag="KR231_002180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBH0004547.1"
                     /translation="MSKLIYIADDEDNIRNLVKTFLKNEGHDVMDFKTGDELLEQFNI
                     KECDLVILDIMMPGSSGFEVCTKLREKSTVPIIMLTARDTDIDYITGITLGSDDYFTK
                     PFSPMSLVMRVKSIFRRIEFEKKQNYDKYSNSIDMELKFGDVIINKKNKIVTSKNVNI
                     DLTPNEYNLLTYLFENIDRAISRDELLNKIWGYDIEVETRAADDTVKRLRKKILDTNI
                     LIETVWGFGFRLKEKS"
     gene            5801..7288
                     /locus_tag="KR231_002181"
     CDS             5801..7288
                     /locus_tag="KR231_002181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBH0004548.1"
                     /translation="MKNGNDKNRIGKIKSKFKLKFSKKNISIKTRILLSILCLIIIVF
                     MIILVSFNVFLDTYIKTTANEELTKSTEIVEHMDSNFRPIKPPQDDGKLPPKVLSNFM
                     RNVQDKVRMAETQSDADAMVVDSKYNLIFPTREDDFLKNVDEMELIRECIQNEKLDLN
                     SDANTRISTRNKDYYISTVKITSIYGEQDKYLILFIDISKTLNLAQKINIVLISVMCF
                     AGILAIFTAVILSEKIAKPIKELCEFAKKMGQGDFKRTYFDFSDKELVELSTVMNKSA
                     EYLDKYDNEQKIFFQNASHELRTPLMSIKGYAEAIKYNVIDSKHASDIILEESDRLSD
                     MVEDLLYISKIDNITKDFELVECDLREVLSNCGARQNVRAINKGIKFIYEFDEEMVLF
                     ECDEKNISKAFMNLIENALRYAKSEIKIVCKYNQKNIVVIIEDDGIGIKKEDLPHVFE
                     RFYKGVGGNHGIGLSIVKSIVNKHGGRIYVENGKKGAKFTILFKL"
     gene            7493..9106
                     /locus_tag="KR231_002182"
     CDS             7493..9106
                     /locus_tag="KR231_002182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diguanylate cyclase"
                     /protein_id="HBH0004549.1"
                     /translation="MKEQLIFNITNLVTVVFEAFVIHMFLSDFLGQKEGYIKVVRYAK
                     LGFIICLGFCNLITLNPKITMPLIFILIFSTSFLYKGNLKTRLFTTVLLSIFFILSEI
                     VVTSIFVLFVKEGFEIMLENNSIRVLATILSKIVFLLTCKIICLFKKDVHLDMPIKYW
                     LPLFLIPIFSLFLSVSIFDVSKFFSLESLKFLSLISSVGILYINFIVFYLFKFIIDKT
                     KLSMKYELLEKEIIHKEELRLSNECYKIIVEQTDSVVFEWNIKENKSFVSQAWTEKFG
                     YNNACKNIFKEIKDKDLVHSEDKAIFEGFLESIKKKNMHNQAVYRLKKSNGEYIWCRT
                     SITSIYNDENELLRVVGVIVDVDSDIKKYEELRTRAESDSLTNIYNKGTFEKLVEETI
                     VMNTGDKKDALFIIDLDDFKEINDNFGHPFGDFVLKTFADKIQTSFGSKDLVGRIGGD
                     EFVVYMQDYVTEVNLHKKAKELNRVLSDNYTDLSFSFDASVSIGIARYPQDGTSFFEL
                     FKNADRALYSIKASGKNSYCLFEEELYVQ"
     gene            complement(9469..10299)
                     /locus_tag="KR231_002183"
     CDS             complement(9469..10299)
                     /locus_tag="KR231_002183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HBH0004550.1"
                     /translation="MSQVSKNYFTTGEFAKICGINKKTLFHYDDIGLFSPELKKENGY
                     RYYSYHQLSIFGIISSLREVKMPLKEIKAYIDKRTPNLLIELLEKKTIDIKNEIEKLN
                     NIQALMESTISFTKNACNIDANTITLKEHEEEYLVKTPVTYKEQFLGDEEENFLYECI
                     NFMDNYELSDYGTIGSIIKGEDIINKDFESYSYLFTKVNKEYKKYPVSIKPKGLYVTA
                     YHKGSYETIYKAYEKLLNFFNQNNLRIGDFVYEEYLLYDISVRDSNEYLTQISAEVKM
                     "
     gene            10372..12099
                     /locus_tag="KR231_002184"
     CDS             10372..12099
                     /locus_tag="KR231_002184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH0004551.1"
                     /translation="MKKLIHFLKPYRVLIVVVLIFTFLQTLGTLYIPTLTANIVNNGV
                     VKGDIDYIVKTGLMMMIVAGITALSAVLVCKVSANLSSGFCRDIREAVFIKSQDLSIN
                     DFNNIGTASMITRSTSDITLIGQSVFMFIQLVLPAPIITVSGLFLAYSIDKAMTIIIV
                     VVMFLFMLSAFLVGKKLIKLFKMMQIKMDNMNRVLREVVTGVRVIRAFNRSHFEKKRF
                     DRTAIDYSETAISINKIFAVLMPIVMLIMNLGIVSIIWFGGMRVSNGNMEIGHIMALV
                     EYCILILFYLIMGVMVFMYIPRAGACADRVNQILDIEPEIVDGNGHKDTVSERGHLVF
                     KNVTFSYAQSEEPVLNNITFEAKSGEVTAIIGSTGSGKSTIANIIPRFFEIQSGEISI
                     NGQDIKKIPQKELRDKIGFVPQKAFLFSGTIEENIRYGKEDASIEEVKHAASIAQADE
                     FISDMEDKYDSFVAQGGNNLSGGQKQRISIARALVRKPEVYVFDDSFSALDFKTDKRL
                     RKALKNEIKDSSAIIIAQRISTIMDANQIIVLNDGKIVGIGKHKDLLENCEVYKQIAD
                     SQLSKEELA"
     gene            12136..13998
                     /locus_tag="KR231_002185"
     CDS             12136..13998
                     /locus_tag="KR231_002185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH0004552.1"
                     /translation="MSEKRIDEQDIEVLSFEDGMSAEKAKDAKKTTKRLLKYMAKQKF
                     KILIIFISVLISSALTVLAPMVMGKAIDQLFNGIKTAVQTGTKFSVNFSTMGGIVSIL
                     LGLYLISAVFIYIQQYIMSGVAQNLVLSMRKDLSDKLNKLPLKYYDSHKKGETLSIVT
                     NDLEKVADSLQEGLMQLITAVVTVVGSIVMMISISVPLTIVSAITLLVSLGITVVIAR
                     KSQERFSENQKALGELNSNIEEIFTGQIVVKAFSKEKDTIRNFKILNQNLYNASRKAQ
                     FSSYAISPIIRFINLIGYVIIAVVGGIFASTGAMTLGSIQAFIQYVNQASEPTTEISY
                     IVNMLQAAIASAERVFTVMDEVEEIKDEESSKVISMPKGKVQFEHVKFGYSDDFILMK
                     DININLNAGDKIAIVGPTGAGKTTLVNLLMRFYEIQGGRITIDGVNIKDLKRGELRTM
                     FGMVLQDTWLFNGSIKENIAYSKSDATMDEIVRAAKSARVDHFIRTLPQGYDTILTED
                     ASNLSQGQKQLLTIARAILSDPSVLILDEATSSVDTRTEVEIQKAMNNLMKGRTSFVI
                     AHRLSTIRDADLILVMKEGTIIEQGSHKELIEKKGFYEELYNSQFTSEYDEDVV"
     gene            14331..15020
                     /locus_tag="KR231_002186"
     CDS             14331..15020
                     /locus_tag="KR231_002186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyphosphate polymerase domain-containing
                     protein"
                     /protein_id="HBH0004553.1"
                     /translation="MNKKLNYRFEMKHKITEADVLALKSRLYQIMKKDENASKDGKYL
                     IRSLYFDTPEDKALLDKLNGVAIREKFRIRFYNNDCSYIRLEKKIKHYNMTSKLSTNL
                     TKKEVINILNNDIEFLKESTNCLLREFYLKLKCERLEAKSIVDYNREAFIYPVGNVRV
                     TIDSDIKTSVNSVDLFNKDLPTVSVIDENMTVLEVKYDEFIPDFIKDLIQINKTTSTA
                     VSKYASSRLYI"
     gene            15125..15811
                     /locus_tag="KR231_002187"
     CDS             15125..15811
                     /locus_tag="KR231_002187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4956 domain-containing protein"
                     /protein_id="HBH0004554.1"
                     /translation="MILIMTFNDIFKSSFIENVSGFSFVDSALALGSAFLVGLFIYMV
                     YKKTYMGIMYSRPFNVSLVALTMLTTFVILAVTSNVVLSLGMVGALSIVRFRTAIKDP
                     MDLVFLFWSLGSGIVLGAGLIPLAVMGSIIMGLILIFFSNKTISETPYILMVNCNNED
                     SEDIATDKIKKVFTKYQIKSKSVTPEKGIELVFEVRMKDGETSLINDLSQVDGVTNAV
                     LVSYNGDYVA"
     gene            15828..17735
                     /locus_tag="KR231_002188"
     CDS             15828..17735
                     /locus_tag="KR231_002188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CotH kinase family protein"
                     /protein_id="HBH0004555.1"
                     /translation="MKDKKFTLLISIMIIFLCAVVGVYSTSSNKSVDLYSDVYIEKYF
                     NRDKVMEVNIEIDESDLKDMNENAIKEEFKVAKVTVDGDTYGNVGIRTKGNSSLISVA
                     NSDSDRYSYKINFDKYNTSQSMEGLTQLNLNNCYSDPSYMREFLTYSICEEMGLATPE
                     FAYAKVSINGEYHGLYLAVEGLKESYLENNFGNVTGDLYKSDEGSSLQYKGDDPESYS
                     NLIVESDKKTADWSKITKLLKSLDTGEDIEKYLDVDSVLKNIAINTALLNLDSYQGSF
                     AHNYYLYEQDGVFSMLPWDFNMSFGGFSGFGGGSQSIAIDEPTTGNLEDRPLISSLLK
                     NETYKTKYHKYLEEIVTKYLDSDYLENMTTKLHDMIASYVKEDPTAFYTYEEFEKNIT
                     SSIEDSSDNKGFGNKGFDNNNSNNSDSNNNSNSENKRSGNQSDEKEVNAELTSSVVKA
                     NTDNETKNKTTNDSESKNNTDKDKSGNDNNQKLEGPMGKGGKSIPGVLEVAEDMSKTI
                     KSQLSGETSSTKQNSGDESSSGIKGSEKFDEDMSGMPEPPEGMDGKMPPGMGNMDKGD
                     MNGKNGNMNMDRNQDNPIEVGGFGNRGGGSVSKTTTYFKLILGGASMIIMSIMLVGVS
                     RVKRRRFIKSK"
     gene            18186..18875
                     /locus_tag="KR231_002189"
     CDS             18186..18875
                     /locus_tag="KR231_002189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0004556.1"
                     /translation="MLQKVLWKFLKLVVGLFICSVGIVLTINCNLGLSPWDVFHQGLS
                     NHIGITIGTASIIVGSIVVIADVVLGENVGWGTVFNMLLIGFFMDLLLYSNLIPEADN
                     LFVGIIMLILGLVLLSVGMVFYMGSGLGSGPRDGLMVAIQKKTGKSLKLIRGTIEVGA
                     LIVGFLLGGKVGIGTIISAFGLGYFTQMVFGLFKLDCSKIKHRFIVDDIKFIKVYMSG
                     EKKAAVQNIVK"
     gene            19311..19850
                     /locus_tag="KR231_002190"
     CDS             19311..19850
                     /locus_tag="KR231_002190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007286148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBH0004557.1"
                     /translation="MDIGEKIKRLRTEKQLTQEELANRCELSKGFISQLENNLTSPSI
                     ATLIDILEILGTNLREFFNEIDDERISFTKEDMFETEDEDLKYKLKWLIPNSQKNEME
                     PIIITLYPGGQYKEEKPHEGEEFGYVLAGSIYVHIGEKKNKVKKGESFYFRPKANHYI
                     SNEGKTTAKVIWVSTPPSF"
     gene            19869..20912
                     /locus_tag="KR231_002191"
     CDS             19869..20912
                     /locus_tag="KR231_002191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011721317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH0004558.1"
                     /translation="MVENIIELRDISKHYEELTVLDNFNLDIKKNEFLTLLGPSGCGK
                     TTTLKIIAGFEYADDGKVLFEGKEINNLPPYERQVNTVFQKYALFPHMDVYENVAFGL
                     KIKKTPKDVIDAKVKEVLKLVALEGFERRQVESLSGGQQQRIAIARALVNEPKVLLLD
                     EPLGALDLKLRQEMQIELKRIQKKLGITFVFVTHDQEEALTMSDTIVVMYKGKIQQMG
                     TPQDIYNEPKNSFVAKFIGESNIFDGIMIEDYKVNFCNRDFECVDKGFEKNENIEVVI
                     RPEDIKMVKPEEGMLKGKVTSTVFKGVHYEIELNENGRLWILHNTKNAEVGTELGMDI
                     YPEDIHIMRKENN"
     gene            20914..21750
                     /locus_tag="KR231_002192"
     CDS             20914..21750
                     /locus_tag="KR231_002192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBH0004559.1"
                     /translation="MKRKSFLAYPYVVWSAIFVIIPLILVVFFSFTKESGGGYAFTLE
                     NYKEVIDPIYMKVFGRSILLAGGATLICLIVGYPVAYIISKARVSRRGSLILLFILPM
                     WMNFLLRTYAWVAILGKNGLLNTFLGWFGIQPLAILYTNFAILLGMVYNFLPFMVLPI
                     YTALSKMDNDLINAAHDLGANNMTVFRKIIFPLSLPGVMSGITMVFMPAVTTFAISRL
                     LGGGKIMLVGDLIEQQFTVVGDWNFGSAISIFMMIVILISMSIMSKFGDESDKEGGGL
                     LF"
     gene            21855..22529
                     /locus_tag="KR231_002193"
     CDS             21855..22529
                     /locus_tag="KR231_002193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBH0004560.1"
                     /translation="MARWNGFTWKWYGQLLQNESIMSALYYTIVIAILASVISTIVGT
                     ISAIGIHKMRGKSKKLILNVNYLPILNTEIVTAVALMSLFVFVKMEFGFTTMLLAHIM
                     FCLPYVILSVLPKMKQLPDNIEDAAMDLGATPIYALRKVILPQIKPGIVSGFLIAFTM
                     SIDDFIISFFNAGNGVSNLSIEIYGMARRGIKPEINALSTIMFAVVLGLLLLANKKES
                     IVRGIK"
     gene            22529..23581
                     /locus_tag="KR231_002194"
     CDS             22529..23581
                     /locus_tag="KR231_002194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728693.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="spermidine/putrescine ABC transporter
                     substrate-binding protein"
                     /protein_id="HBH0004561.1"
                     /translation="MIKFKKAISLIAVGMMTVTLFTGCNKATDSTKVLNVYNVGDYID
                     ESLIDKFEKETGIDVQYSTYDTNEMMYQKVKSGSTHYDLVFPSDYMVEKMKNEGLLEK
                     LDFKNIPNMKYLDKSFLNPVYDKTNEYSVAYMWGTLGILYNKKEVKDPMDSWNILWNP
                     KYKGNIMMFDSVRDTIGITLKKLGYSMNSVNPKEINEAKNLLMKQKDLVLAYVNDEGK
                     DRLLGGEVAMGMLYSGDAVTLMEQNPDLDYAIPKEGTNKWVDAMCVPTTAQNKKEAEL
                     FINFLLDPENAKVNAEYIGYSTPNTGALKLLDPEITQNPVAYPSKEVLDKCETFEDIG
                     ENIKLYDKAWIELKSK"
     gene            23811..24659
                     /locus_tag="KR231_002195"
     CDS             23811..24659
                     /locus_tag="KR231_002195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GGDEF domain-containing protein"
                     /protein_id="HBH0004562.1"
                     /translation="MNRINKKIDLLILALLVFIFLIVGIVILSIRTENKLNVFIMLAI
                     IFFIIMLTYLSNSVVGLITSSIIIFMYTSYILYNNITHNMDVEFISYMWIIATPVSSI
                     IMGNLNKSINELQNTNKKLSEQYKELVTIDSETGLRNLKIFYNDVNMEISKSIRHNTD
                     FSLMIVKLPYYGNLQTIFGENKTNKIVKYIGSNIIECTRNEDIIYSLQKDMIGILMPN
                     TSLEGSKVVKDRIKKRIKELNLDLNNRGKYVNIDVKIAFLQYKSSFGDSINFKNIVEE
                     ELQYDV"
     gene            24649..26313
                     /locus_tag="KR231_002196"
     CDS             24649..26313
                     /locus_tag="KR231_002196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HBH0004563.1"
                     /translation="MMFKIFNKSLLKLVVVLSIVLTISNFSLSSYASEITSSTDKVLI
                     IYDSKKETAYNRDILNIMRTLLGRFSSDIELLKLSNYDGEINKNYYSHIFILGINENS
                     YNNDKNTKNLISSLNSYKGTICWLGYGIENLLEHKKYNLDYVGKTNNIVSVNYRGKSY
                     NLDEHYVFNIVESKDTSNKVIGSINDTLNKYPYIINDKNLFYVSKLDLDGVLFYIFCD
                     SLNDIFNIKTFDKGRIFVRIEDVHAFREPKNLVEIADYLSSKNIPFTIALIPAYVNPK
                     NHKVITLSESPEIVKAIKYMQDKGGTVILHGYTHQYKKEEVSGEGYEFWDGKKDEPLK
                     ENMKIFVKDRVLNGLRVCIENGIYPLAFEAPHYAMESEGYKELKKYFSTYMGQHQNND
                     KKFSTNTYPYIIRDTEEFNIFIPENLGYIDPEDKFTFQNIKENLNKLSIVRGFSGGFF
                     FHSYLNIEYLKNTIEYLEKQNIEFMNLRDFNNWVKVDEIQIRNNGDEIIVNYDKDLDE
                     ITKSDTRFKSISNISKVLIFIVSISVLIFVIIFIYFKRIDKKKFLK"
     gene            26362..27618
                     /locus_tag="KR231_002197"
     CDS             26362..27618
                     /locus_tag="KR231_002197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003362983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HBH0004564.1"
                     /translation="MRDLNVSEYLFVFSLFSIWSLLLINIILAMGGYIFYFKNFDKEI
                     KEIDEYPMISILVPAHNEAKVIGRTVESLLLLNYPKSKMELIVINDNSSDNSKEILEN
                     IKDRYNNYNFTIINTDSLTGGKGKSNALNIGYTISKGDFIAVYDADNTPDKNALRYLV
                     QTIVMNDELGAVIGKFRTRNKNKNLLTKFINIETLSFQWMSQAGRWQLFNLCTIPGTN
                     FILRRSIIEEIGGWDSKAIAEDTEISFRIYKLGYKIKLVPQSITWEQEPETVKVWIKQ
                     RTRWAKGNIYVLMKYIKNIFKQGRNKIVFDIAYFFSVYFLFLTSVIISDILFVLSISK
                     LVEISIPINFFLIWILSYLLFIIEVSISLTIEKGEATIENIFIVAIMYFTYSQLWLFV
                     AIKGMIEYLKDIIFKREVKWYKTERF"
     gene            27641..29722
                     /locus_tag="KR231_002198"
     CDS             27641..29722
                     /locus_tag="KR231_002198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cellulose biosynthesis cyclic di-GMP-binding
                     regulatory protein BcsB"
                     /protein_id="HBH0004565.1"
                     /translation="MKKFIISIISLVLFFSNISLIYKVNADETKVKNYKFERDITIDG
                     VIGSNSTFFEVNKNWDIEEVLLHLNFSKSQILNGDVSSLTVLINNVPIKSIKLNAKTN
                     YKNTLEVLVPKDYIIQGYNEIKIKTYKTISDKICQDDSNTGNWMVIHKESYISIRYKQ
                     KKVENSINEYPYPYAEIENNHKLDTTIVVPDNMTRGETTAVFNLASAFGKITKNDDLK
                     LDVKLYSEMKNWSDDNIIYIGKPENTAEEILDILSIKEQTLLSSNCIIKQVDSPYNKN
                     KKMMVVIGSNEDDLIKASNLLIENRLSNQVLSSSVLVNKETNIKINREQKLNLGHLTL
                     KDLGYSDFLLEGAFNQQALFDVKIPTGKVLDDGSKIILNLRYSDNLDFEKSLVTVSIN
                     DVIVGSKKLDRSHSNNDKLELKIPKDIDNKNYYQVKLTFNLSIKNSNCVTRESNNPWA
                     YVSNNSYLALSMKENETLSFENYPYPFVRDDEFNDLTVIMPDYSGSQAMTWMFRLGVT
                     LGANINSHNGNINVIRGKEFSDKYKDTNIVVFGVPHNNSVIKMLNNNLNIKFDKNYSN
                     FISNDKISFIDDYGKNISTIQLIKSPYNNQKNIMVISSMNEKNLYLGMDYLLNKSKVN
                     DLKGDTLIIDEYGEVEDLAYNLKSKKEVKDSSWNMSINKTTKVFLMISFITIIVVMIL
                     SMLYIKKYKRR"
     gene            29759..30844
                     /locus_tag="KR231_002199"
     CDS             29759..30844
                     /locus_tag="KR231_002199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888788.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrolase"
                     /protein_id="HBH0004566.1"
                     /translation="MRKYMNKFKLKRSILISLIILIFIFIVYFVSIELKDRSLVNNQY
                     KGKIKSANLSVDYEINQVMKDIDKLGLNTVNVPIIINVESINSDIMSIDNNSKEKAIK
                     LIKKLNKKGISTILEAYPWIENGKLYETDWNPINKKRFFYTWQNAILNELIIDVANPL
                     DVNVLNIGSNFVHLEEYQQNWGEIIDFVQSKFDGFVTYRTNWWYTKKDDLSSKLFYEQ
                     KLNNNFFDKLDFISIAAYFELSNKPVNTVDELISALHSSTVNNRGQNIKQEIYNLYKA
                     HRKPIFFGELGFSNRESASSQPWNHTPSKAVNGEEQARCFEAYKKVFENEDWINGFSV
                     FCVGKIDDEKNFYPSKESIKVIKSWYE"
     gene            30898..32022
                     /gene="wecB"
                     /locus_tag="KR231_002200"
     CDS             30898..32022
                     /gene="wecB"
                     /locus_tag="KR231_002200"
                     /EC_number="5.1.3.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine 2-epimerase
                     (non-hydrolyzing)"
                     /protein_id="HBH0004567.1"
                     /translation="MNDIKVMTVFGTRPEAIKVAPLIKELEKRENIKSIVCVTAQHRE
                     MLDQVIETFNINVDYDLDIMEKGQSLNDITCKILNKLPLILNKENPNIILVHGDTTTT
                     LATSLTAFYNKTLVGHIEAGLRTYDKYSPFPEELNRQLTGIIADMHFAPTNLARKNLI
                     SEGKPNNNIFVTGNTAIDALKMTIKENYNHPIIDEIGNDRMILLTSHRRENLGKPMKN
                     IFRAIKRIVDDFEDVQIVYPIHLNPKIRTIADEIFGKFPEKIHIIEPLDVADFHNFLN
                     KSYMIMTDSGGMQEEAPSLGKPVLVLRDKTERTEGIEAKTLKLVGTNEDRIYNSVSDL
                     LINKDNYVQMSKASNPYGDGNASKYIVDIIIKKFNCKYLN"
     gene            32100..33074
                     /locus_tag="KR231_002201"
     CDS             32100..33074
                     /locus_tag="KR231_002201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosaminidase domain-containing protein"
                     /protein_id="HBH0004568.1"
                     /translation="MARKLIKNLGKSKSVKRVKLLFKKIFITVFIVASIVAIFNITKY
                     FEELYKVRDLKSTKIEYYMDVADEAGDGKVQLSWKALLAIDMVIHDEDLSNIKKKDTL
                     DIGEKFIVEDKNDKGEKVYKVKKFNKVLSELKFDSSQKSRARKYMKDLEYTYLGNKQL
                     DSSDEKIKFIKKLEDSAIREYIDYGILPSITIGQAILESGWGNSKLTKQSNNLFGIKA
                     DKAWKGKSVEISTSEHYNEKIVASFRSYNSLQDSVKDHSLFLINNKRYRKHGLFEAKD
                     YISQAQSLENAGYSTAEDKKGNRIYAELLIDVIRSYNLQLIDNKVETK"
BASE COUNT        13227 a         3365 c         5604 g        11021 t
ORIGIN      
        1 gtaaaaatga aatagaaaat atttttcatt tttacttcgt tttttatatt ataaaatttt
       61 tgttatgtta caaaatttct ataaagatga tgtgaatcta aacattatat gacaacgtga
      121 gcatttaagt taaaatattt taaatatact attttagata agttccctct tcatcttgat
      181 aaattaatcc ttttttcata agcactccaa gagctcgttt aaaatttttc ttacttgaat
      241 taaataatat agaaatatct ttagggtcag atttatcatt aaatctcata tatccatcag
      301 aaccttctaa ataacttaaa atcttatttt ctaaagtatc aagttcatcc tttctatttc
      361 ctctaggaga aagaccaagt tttccatctt catatatttt tatgacatgt aaattttcaa
      421 gaacatcacc agtttttagt tcagtaaagt actcattatg aagtattaca ccagcatatt
      481 tattgtctac acatatcatt gcagaattat tagtttggaa tccatataca actccagtta
      541 caatatctcc tacattgtaa gtatggtctg ttaataagta tgaatctata tctgtagtag
      601 cagcaattct tttgcttttg tctaaatata tataaaataa atatttttcg tctctaaata
      661 gtggataagt cttagcttta aaaggaacta atatgtcttt aggaagtccc atatctataa
      721 aagtaccaat gtctgtatta tcaactactt ttaaatgtgc tacatcccca accttagcta
      781 aaggcggtat taaagttgca gcagttctgt catcagaatc tttaaatatg aaagcattta
      841 cttcatcacc tatgtttatt tcattttttc cgattaatct attatgaaga agtatatcgt
      901 cttttgtgtt attagtttgt ccatccaaaa aatatccaaa ttcagttttt ctttttactg
      961 taagtttatt aaaatcacct atgtttatca aattaaaatc atcctctcat tttatattta
     1021 taatttagcc ataatatact tatgtagtag tttgtcacag tatctatatt agtattagtg
     1081 aaatttacaa taaataatat agttatttat gtatttttca attctctagc ttcttatata
     1141 gtataaactc caatttcttt tttgtcttta ggttttatta aaatttttac aaaataagtt
     1201 aaaaagtatt gaaataaaat ttcttttaaa gtataattgg tatataccaa aattggtata
     1261 taccatatcg aaaagtggtg actatatgaa aatagtaaat aaatctagta atataccatt
     1321 gcatactcaa ttaagttcaa taataagaga gatgatagaa actggtgagc ttaaagaggg
     1381 cgatgcaata atgccagaaa gagaactttg caacatacaa aatgtaagtc gtatgacagt
     1441 aaataaaacc attgttggat tagttacaga aggacttctt tatagggtac aaggtaaagg
     1501 gacattcgtt gcaaagcaaa aaaagaagta tcagttttca aatgtaaaag gttttactga
     1561 tgttatgaaa gaaaagggag taaacataaa aacggatata ttatcctttg agatggaact
     1621 accagatgat ttagttaaaa gaaagcttgg aataagtgat aatactacaa atatatataa
     1681 gattgtcaga cttagatata ctgatggaga gccatttgga ttagaaatag tatatctatc
     1741 agaagaaatg tgtaagggtc taacaaaagg gatattggat aattcttcat tatatagggt
     1801 tttaaatgaa aaatatggct ataagataca aaaagctgaa caggtaatgg agccagtaat
     1861 actttcagat gaagaaagta agcttcttga aacagatgaa ggtgctttag ctcttaaact
     1921 tcatagaaat tcctataata gagaaggtag acctatagaa tataccatat caatatttag
     1981 aacagataaa tatcaatatg aaatagtatt gagtgagtag gtgaataata tgaaatgttt
     2041 aattaatgga aagataatat taaaaaatca aatcttagaa aataaagtat tagtatttga
     2101 tgaaaaaata attgatatag ctgatagtgt accaaaagat tgtgaagtta tagatgctga
     2161 tggaaaatat atatctccag ggcttattga tattcatata catggaaaca tgggaaaaga
     2221 tacaatggat tcgactgatg aatctattga aacaatttca aaatcaatta tgagacatgg
     2281 agtaacatct tttcttccaa ctacaatgac tatggataaa gaacatgttt atgatgcact
     2341 tgaagttatt aaaaaagccc aaaatagaaa gcttgaaggg gcacaagtat taggagcaca
     2401 tttagaagga ccttttataa atgagaatta taagggagca caaaatgaaa aatttataat
     2461 aaattcaaaa tacgaattta taaaagaata taaagatgtt ataaaagtta taacttatgc
     2521 tccagaaaaa gatattgatt ttgattttac tagagaaata aaaagatgta cagatatagt
     2581 tttatctatt ggtcatagta atgcaaatta tgaccaagct aaagaagcta taaatttagg
     2641 agtaactaat gtaactcaca tgttcaatgc aatgactggt ttaaaccata gagacccagg
     2701 cgttgttggt gcagcactta caactaatgt gtacagtgag ttaatagcag atacaatcca
     2761 tataaataaa gatttatttc aatttatact aaataataaa ggaaaagaaa gactgatttt
     2821 aataacagat tctatagaag ctggtggtct tgaagatggc aattattctc ttggaggtca
     2881 gaaagtcata gttaagggta atgaagctag acttgaaaat ggagcattag ctggaagtgt
     2941 gttgtcttta aataaaatgg tatttaactt cttaaataat acaaacctta aagtgaatga
     3001 agcaattaat ttagcttctt taaatccagc aacatctttg ggaataaatg acaaaaaagg
     3061 aagcttagaa ataggtaagg atgcagatat agctgtattt gatgagaatt tagattgtaa
     3121 aatgacactt tgcttggggg aagtagtata taaaaatata tagtatacaa aacaaacctt
     3181 aaagacagta aaaacaatat aaaaaataat aaattaaact tacattagta aaagtagtag
     3241 ttaaaattta ggaggaataa gatgagagta ttagtgtgta aagattatga tggaatgagt
     3301 aaaaaagccg ctgaaatgat agcagctcaa atagttttaa aaccaaattc aatactggga
     3361 ctagctacag gaagtacacc agtaggtatg tatagagatt tagtaaaaaa atacaatgat
     3421 aatatagtag atttttcaga tgtgatgagc tttaatttag atgaatatta taagttacca
     3481 atatctaatg accaaagcta tgattatttt atgaaagaga atctatttaa tcatgtaaac
     3541 ataaagccag aaaatactca tctaccaaat ggaatggctg atgatattga aaaagagtgt
     3601 atgaactatg aagcttctat agatgcagct ggtggtatag atgtacaagt acttggaata
     3661 ggtcgtaatg ctcatatagg ttttaatgaa cctgatacta aatttgcaaa aagaactcat
     3721 gtagttgaac ttacagaatc tacaatagaa gctaatgcaa gattctttaa atcaagagaa
     3781 gatgttccta aaaaagctgt aagtatggga ataggttcaa tattgaagtc taagaaaata
     3841 ttgcttttag cttcaggaga agaaaaagct gatgcagtat ataatactgt ttacggagat
     3901 ataactccag aagttcctgg ttctatactt caacttcata aagacactat agttatagta
     3961 gatgaagcag cagcaagtaa attgaatcca aaagattata aattagtata agaatagaat
     4021 gtagtttaaa taaaaaatag ctatcattga ataatcaaat ttatttaatg atagctattt
     4081 ttatttaaat tagttattat tgtttaaatt acttgcttat tactttttac gaaaactcgt
     4141 tatcaagaag tatccaaata agatgttaaa aattattatg tttagtggga ttctatcaag
     4201 cataataaaa ttacctataa ttgggatatt accaactgga aacataaaga agaatacagg
     4261 catcagtgat agtaaaaaag atggaaaaca aagaagaagt aatcttggaa tatcaatata
     4321 ccaactacca tcctttttgt attctctaat caataattca gttcctagta ataaaccaat
     4381 accaccagag gaaattaaat taataaaaat gtatctttta aagtcttgca tataaccagt
     4441 gtaaaattga gtatagaaat cataatttaa tttaacggct aaaaaataca taagcaatag
     4501 aatgattaaa aataaaagat atctaagagc ttttttcatt ttaaattctc ccttcagaaa
     4561 tactttattt agttttattt tgttggaatc tgattttatc atttagttta agaaatccat
     4621 aatattagtg aagaatgaaa taagtattat atatgaataa atatttttag aattaaggtg
     4681 aattgtagtg cttaatataa ctataatatt aattgtttga atattcaata aaaagttcga
     4741 aaaatatcaa ttctgatata aactgaataa atacagttga atattaaatt attattttat
     4801 caaaaatatg caaagtacta caccttcaaa tatcacctaa agtaattaaa aggcaattaa
     4861 agtgaagtag ttcaagtatt tctaaaataa gtttaataaa ttctataata atttattttt
     4921 tgccttaaaa ttgccttaaa atccaaacaa ttttaaaact aatgtactat aaaaagctgg
     4981 tataatttaa atatagtaaa aaataagatt tatcttatct attgggattt aattatttaa
     5041 tcaatatatt tataccattt aatttaaata aaaagtctat taaggagtga gcttatgagt
     5101 aagttaattt atatagcaga tgatgaagat aatataagaa atttggtaaa gacattctta
     5161 aaaaatgaag gtcatgatgt tatggatttt aaaacgggtg atgaactttt agaacaattt
     5221 aatataaagg agtgtgactt agtaatacta gatataatga tgcctggctc aagtggtttt
     5281 gaagtatgta caaaacttcg tgagaaaagt acagtcccaa taatcatgct tactgcaaga
     5341 gatacagata tagattatat tacagggata accttaggta gtgatgatta ttttacaaaa
     5401 ccatttagcc caatgtcttt ggttatgaga gtaaaatcta tatttagaag gatagagttt
     5461 gaaaagaaac aaaattatga taaatatagt aactcgatag atatggaatt aaaatttggt
     5521 gatgtaataa taaataaaaa gaataaaatc gttacaagta aaaatgtaaa tatagacctt
     5581 acaccaaatg aatataacct attgacttat ttgtttgaaa atatagatag agcaatttcc
     5641 agagatgaat tattaaacaa aatatgggga tacgatatag aagttgagac aagggctgct
     5701 gatgatacag tgaagagatt acgtaaaaaa attttagata caaatatttt aatagaaact
     5761 gtatgggggt ttggatttag gttgaaggag aaaagttaag atgaagaatg gaaatgacaa
     5821 gaatagaatt ggaaagatta aatccaaatt taaattaaag ttctcaaaga aaaatataag
     5881 cataaaaact aggattttgt tgagtatact ttgtttgata attatagtat ttatgataat
     5941 attagtatct tttaatgtat ttcttgatac atatataaaa acaactgcga atgaagaatt
     6001 gacaaagtct acagaaatag tagaacatat ggatagtaat tttagaccta ttaagccacc
     6061 acaagatgat ggaaagcttc ctcccaaagt attatctaat tttatgagaa atgtacaaga
     6121 taaagttagg atggcagaaa cacaatcaga tgctgatgct atggtagttg attctaagta
     6181 taacctgata tttccaacaa gagaggacga tttcttaaaa aatgttgatg agatggagct
     6241 gattagggag tgtattcaaa atgaaaaatt agatttaaat tcagatgcaa atacacggat
     6301 atctaccaga aataaggatt attatatttc aactgtaaaa attaccagta tatatggtga
     6361 acaagacaag tatcttatac tttttataga catatcaaaa actctaaatc tagcacaaaa
     6421 gataaatatt gtattaatat ctgtaatgtg ttttgctgga atattagcaa tatttacagc
     6481 tgtgatttta tctgagaaaa ttgctaaacc gataaaagag ttgtgtgagt ttgcaaaaaa
     6541 aatgggtcaa ggagatttca aaagaaccta ctttgacttt tcagataaag aattagtaga
     6601 gctctcaact gttatgaata agagtgctga gtatctggat aagtatgata atgaacaaaa
     6661 aatatttttt caaaatgcat ctcatgaatt aaggacacca cttatgtcta ttaaaggtta
     6721 tgcagaagct ataaaatata atgttataga tagtaaacat gcaagtgata taattcttga
     6781 agaaagtgat aggttaagtg atatggttga agatttatta tacatttcta aaatagataa
     6841 tataactaaa gattttgaac ttgtagaatg tgatttaaga gaagtacttt caaactgtgg
     6901 agctaggcaa aatgtaagag ctataaataa ggggataaag tttatttatg aatttgatga
     6961 agaaatggtt ttatttgaat gtgatgaaaa aaacatttcc aaagcattta tgaatcttat
     7021 agaaaatgct ttgagatacg ctaagagtga aataaaaata gtgtgtaagt ataatcaaaa
     7081 aaatatagtt gtgataatag aagatgatgg aattggaatc aagaaagaag atttacctca
     7141 tgtttttgaa agattctata agggagtagg aggaaatcat ggaattggat tatcaatagt
     7201 taaatctatt gtaaataagc atggtgggcg tatatacgta gaaaatggca aaaaaggagc
     7261 taaatttact atattattta aattgtaaaa aaattagaga aaatatagag atgtttgaag
     7321 ttgtttttta tatatatctg ttgtatactg ttgaaaaaag aacaatatta agctgacata
     7381 tattacgata gttgacattt aaagtaaatg cttaaatata gatacgaaag gaaaagtaaa
     7441 atctgaagtg tatttaggtt taagtaagct tcttatttta taaaaaatat gtatgaaaga
     7501 acagctgatt tttaatatta caaatttagt aacggttgta tttgaagctt ttgtcatcca
     7561 tatgttttta tcagactttt taggccagaa agaagggtat ataaaagttg taagatatgc
     7621 taaactgggt tttataatat gtttaggatt ctgtaattta ataactttaa accctaaaat
     7681 cacaatgcct ttaattttca tccttatttt ttcaacatca tttttatata aaggaaattt
     7741 aaagacacga ttgtttacta ctgttttatt aagtatattc tttatactgt cagaaattgt
     7801 agttacaagt atttttgttt tatttgtaaa agaaggcttt gaaataatgc ttgaaaataa
     7861 tagtataaga gtattggcga caattttatc taaaattgtc tttttgttga cttgtaaaat
     7921 tatttgtcta tttaaaaaag atgtacattt agatatgccc ataaagtatt ggctcccttt
     7981 atttttaata cctatattta gtttatttct gtctgtttct atctttgatg taagtaaatt
     8041 ttttagtctt gaaagtttaa aatttctaag cttaatatct agtgttggta ttttatatat
     8101 taattttatt gtcttttatt tatttaaatt tattatagat aaaactaaac tatctatgaa
     8161 atatgaacta cttgaaaaag aaataattca taaggaagaa ttaagactta gtaatgagtg
     8221 ttataaaatt attgttgaac agactgattc tgtcgttttc gaatggaata tcaaagaaaa
     8281 taaatcattt gtatcgcagg cttggactga aaaatttgga tataacaatg catgtaagaa
     8341 tatttttaaa gaaattaaag ataaagactt agttcattct gaagataaag ctatatttga
     8401 aggttttctt gaaagtatta aaaaaaagaa tatgcacaat caagcagtat atcgtttaaa
     8461 aaaatctaat ggtgaatata tttggtgtag aacatcaatt acaagcattt ataatgatga
     8521 aaatgaactt ttaagagttg tcggagtaat tgtagatgta gatagtgata taaaaaaata
     8581 tgaagagtta agaactagag cagaaagtga ctcattgacc aatatataca ataaaggtac
     8641 atttgaaaaa ttagtggaag aaactatagt tatgaataca ggtgataaaa aagatgcatt
     8701 attcattatt gatttggatg attttaaaga aataaatgat aattttggtc atccatttgg
     8761 tgattttgta ctaaaaacat ttgctgataa gatacaaact agttttggta gtaaagactt
     8821 agtcggaaga attggtggag atgaatttgt tgtatatatg caagattatg ttacagaagt
     8881 aaatttgcat aaaaaagcta aagaattaaa tagagtactt tcggataatt acactgattt
     8941 gagttttagt tttgatgctt ctgtcagtat aggtattgca aggtatcctc aagatggaac
     9001 ttcatttttt gaattgttta aaaatgcaga tagagcactt tatagcataa aagcatcagg
     9061 taaaaattca tattgtttat ttgaagaaga actatatgta cagtgaattt gaatttagat
     9121 tttatgtgag agtaagattt atatatactt gtggctgtct gatttataaa atatgttact
     9181 ttgtatattt ttatatgttt cagtaaggtt aattaacata agcaaaggtg taagtaaatt
     9241 tatattagtt taagtttact tacaccttta taaaaataca aataatagat tcatttacat
     9301 tcttaaatga ttaaagctct ttaccttcta aacatgcata acatatcgtt ataattccag
     9361 taaataagac taaaataccc attcctaaga ttacagtttc attatctatt actccaaatg
     9421 tttttaaagt aacttatttc gctttgtatc ataataattt gtctcttttt acattttaac
     9481 ttctgctgag atttgagtta gatattcgtt agaatctcgc acacttatat catatagaag
     9541 atattcttca taaacaaaat ccccaatacg taaattattc tgattaaaaa aatttaataa
     9601 cttttcataa gccttgtaaa tagtttcata actcccttta tgataagcag ttacataaag
     9661 tccctttggt ttgattgata caggatattt cttgtactct ttattaactt ttgtaaataa
     9721 atatgaatat gattcaaagt ctttattaat tatatcttca cctttaatga ttgagccaat
     9781 cgtaccataa tcactcaatt catagttgtc cataaagtta atacattcat ataaaaaatt
     9841 ttcttcctca tctcctaaaa actgttcttt atatgtaaca ggtgttttga ccaagtactc
     9901 ttcttcatgt tcttttaaag taatagtatt cgcatctata ttacaggcat ttttagtgaa
     9961 tgaaatagta gattccatta gagcttgaat attatttagt ttttcaattt catttttaat
    10021 atcaatggtt ttcttttcta aaagctcaat tagtaaatta ggtgttcttt tgtctatata
    10081 agctttaatt tcttttaaag gcatttttac ttccctaagt gaagaaatta taccaaaaat
    10141 gctaagttga tggtatgagt agtatctata tccattttct ttctttaatt ctggtgagaa
    10201 aagacctata tcatcataat ggaaaagtgt ttttttattg attccacaaa tctttgcaaa
    10261 ttctccagtt gtaaaataat tttttgaaac ttgactcata attataattc ctccttgact
    10321 atcctgttac agtatagttt atcatagtat tttgtaaagg agtgtgatta tatgaaaaaa
    10381 ttaattcatt ttttaaaacc atatagagtt ttaattgttg tagttttgat atttacgttt
    10441 ttacaaacac ttggaacttt gtatatacca acacttacag caaatatagt aaacaatggt
    10501 gtagtaaagg gagatataga ttatattgta aaaacaggtt taatgatgat gatagtagct
    10561 ggtataacag ctttatcagc tgtgttagtt tgtaaagtat cagcaaatct ttcatctgga
    10621 ttttgtagag atattagaga agcagtattt ataaaatcac aagatttatc aataaatgat
    10681 tttaataata taggtacagc atcaatgatt actaggagta ctagtgatat tactttaata
    10741 ggtcagtctg tgtttatgtt tattcaatta gtattaccag caccaattat aactgtttct
    10801 ggtctattct tagcatattc tatagataaa gcaatgacaa ttattattgt tgtagtaatg
    10861 tttttattca tgctttcagc atttttagtt ggtaaaaagc ttataaagtt gtttaaaatg
    10921 atgcaaataa aaatggacaa tatgaatagg gtgttacgtg aggtagtaac tggagtaaga
    10981 gttataagag cttttaatag gagtcatttt gaaaaaaaga gatttgatag aactgcaata
    11041 gattattctg aaacagcaat ttcaataaat aaaatatttg cagtacttat gcctattgta
    11101 atgttaataa tgaatttagg tatagtaagt attatttggt ttggtgggat gagagtcagt
    11161 aatggaaata tggaaatagg tcatataatg gcacttgttg aatattgtat cttaatttta
    11221 ttctatttaa tcatgggagt aatggtattt atgtacatac ctagagcagg tgcatgtgca
    11281 gatagagtaa atcagatatt agatatagaa cctgaaattg tagatggaaa tggtcataaa
    11341 gatactgtct cagagagagg acatttagta tttaaaaatg taaccttttc atatgcacaa
    11401 tcagaagaac ctgtgttaaa taatataaca tttgaagcaa aatctggaga agtaactgca
    11461 attataggaa gcactggctc aggcaaatct actattgcaa atataatacc acgttttttt
    11521 gaaattcaat ctggagaaat atctataaat ggtcaggata ttaagaagat tcctcaaaaa
    11581 gaacttagag ataagattgg atttgtacca caaaaagctt ttttatttag tggaacaata
    11641 gaagaaaata taaggtatgg aaaagaagat gcaagtattg aagaagtaaa gcatgctgca
    11701 agtatagctc aagctgatga atttatttct gatatggaag acaagtatga ctcatttgta
    11761 gcacaaggtg gaaataattt gtcaggtggt caaaaacaga gaatatccat tgcaagagcg
    11821 ttagttagaa agcctgaagt atatgtcttt gatgatagtt tttctgcatt agattttaaa
    11881 acagataaaa gacttagaaa agcgttgaaa aatgaaatca aagattcatc agctataatt
    11941 atagcacaac gtataagtac aatcatggat gctaatcaga ttatagtttt aaatgatgga
    12001 aaaattgtag gtattggaaa acataaagat ttacttgaaa attgtgaagt ttataagcaa
    12061 attgcggatt cacaacttag taaagaagaa cttgcataaa atgaagaatt aatctgatat
    12121 ttggaggtgt atgatatgag tgaaaaaaga atagatgaac aagatataga agtacttagt
    12181 tttgaagatg gcatgtcagc agaaaaagct aaggatgcaa aaaaaactac taagagatta
    12241 ttaaaatata tggcaaaaca aaagtttaaa atattaatta tttttatttc agtattgata
    12301 agttcagcgc ttacagtttt agcacctatg gttatgggaa aagctattga ccaactattt
    12361 aatggaataa aaactgcagt ccaaacaggt acaaaattca gtgtgaattt tagtactatg
    12421 ggggggatag tatcaatact tctagggttg tacttaatta gtgcagtatt tatatatatt
    12481 caacagtata ttatgtcagg agttgcacaa aatctagttc ttagcatgag aaaagattta
    12541 agtgataaac tcaataaact tcctcttaag tactatgatt ctcataaaaa gggggaaaca
    12601 cttagtatag taacaaatga tttagaaaaa gtagcagata gtttacaaga aggattaatg
    12661 caacttatta cagcagtagt tacagtagtt ggttctattg taatgatgat aagtataagt
    12721 gtaccactta caatagtatc agctataaca ttacttgttt cattgggtat tactgttgta
    12781 attgcaagaa aatcacaaga aagattctct gaaaatcaaa aggcactagg agagttaaat
    12841 agcaatatag aagagatatt tactggtcaa atagtggtta aagcatttag taaagaaaag
    12901 gatactataa gaaactttaa aatattaaat caaaatcttt ataatgcaag tagaaaagca
    12961 cagttttcgt catatgcaat atctccaatt attagattta taaacctaat tggctatgtt
    13021 attatagcag ttgtaggtgg gatatttgca tcaactggag caatgactct tggtagtata
    13081 caagcgttta ttcaatatgt aaatcaagca tcagagccta ctacagaaat atcttatatt
    13141 gtaaatatgc ttcaagcagc aatagcatct gcagagagag tttttacagt tatggacgag
    13201 gtggaagaga taaaggatga agaatcttca aaggttatta gcatgcctaa aggtaaagta
    13261 caatttgagc atgttaaatt tggatatagt gatgatttta ttcttatgaa agatattaat
    13321 atcaatctaa atgcaggaga taagattgca attgttggac ctacaggagc tggaaagaca
    13381 actcttgtaa atttacttat gagattttat gagatacaag gtggaagaat tactattgat
    13441 ggtgttaata taaaagattt aaagcgtgga gaacttagaa ctatgtttgg tatggttctt
    13501 caagatacat ggctgtttaa tggaagtata aaagaaaata ttgcatatag taagtcagat
    13561 gccacaatgg atgaaattgt aagagcagca aaatcagcaa gagtagacca ttttataagg
    13621 actttaccac aagggtatga cactatattg actgaggatg cttctaatct atctcaaggt
    13681 caaaagcaac ttctaacaat tgccagggca atactttcag acccatcagt attgattctt
    13741 gatgaagcaa catctagtgt agatactaga acagaggtag aaattcaaaa ggcaatgaat
    13801 aacttgatga agggaagaac tagttttgtt attgcacata gattatcaac tattcgagat
    13861 gctgatttaa tattagtaat gaaagaagga actattattg aacaaggaag ccataaggaa
    13921 cttattgaaa agaaaggatt ctatgaagaa ctttataaca gtcaatttac aagtgaatat
    13981 gatgaagatg ttgtatgatt atcaagtttt aggcaactaa atgattgata aatattaagt
    14041 taaatatagt aacatgtaag gttatatgga ataagagtat ttctctattt catataacct
    14101 tttttattta tcaaaataag ataaaatttc ctttctaaat tagattgaag aatgtattta
    14161 tcaatataaa agtaaaataa tcattattat tagtgaagta aatattgttt gccacatata
    14221 tgccataaag atgcacttat tttacggaga tttaacaaag tagtgtaaag tatactctaa
    14281 atataaaata aatcaaatag agttaaataa attgagaggt gatataaata gtgaataaaa
    14341 aattgaacta tagatttgaa atgaagcaca aaataactga agcagatgtg ttagctttaa
    14401 aatcaagact ctatcaaata atgaagaaag atgaaaatgc atctaaagat ggaaaatatc
    14461 ttattaggag tttatatttt gatactcctg aagataaagc acttttggat aaattaaatg
    14521 gcgttgcaat aagagaaaag tttaggataa gattttataa taatgactgc tcttatataa
    14581 ggctagagaa aaaaatcaaa cattacaaca tgacatcaaa gctatcaact aatttaacca
    14641 aaaaagaagt aataaatata ctaaataatg atattgaatt tctaaaagag tcgacaaatt
    14701 gtttattaag agaattttat ttgaaattaa aatgtgaaag attagaggca aaaagcatag
    14761 ttgattacaa tagagaagct tttatttatc cagttggaaa tgtaagagtt acaatcgata
    14821 gtgatattaa aacttctgta aattcggtag atttatttaa taaagatttg ccaactgttt
    14881 cggtaattga tgagaatatg actgtattgg aggttaaata tgatgaattt ataccagatt
    14941 ttataaagga tttaattcaa attaataaga ctacctctac agcagtttca aagtatgctt
    15001 caagtagatt atatatttaa gaataaaggc tatgatttat ataaagatat acataaataa
    15061 ggttaaaaaa caaataagtt aaaaataaat aaaataaaaa ataaataagt taaaaatagg
    15121 aaggatgatt ttaattatga catttaatga tatttttaaa tcaagtttta tagaaaacgt
    15181 atcaggtttt tcatttgtgg acagtgcttt agcactaggt tcagcttttt tagtaggttt
    15241 gtttatatat atggtctata aaaagactta tatgggaatt atgtattctc gaccattcaa
    15301 tgtgtcgctt gtagcactta caatgcttac aacttttgta atattggcag ttacttcaaa
    15361 tgtagtttta tccttaggta tggttggtgc tttatctata gtaagattta gaacagcaat
    15421 taaagaccca atggatttag tatttctatt ttggtcattg ggttcaggta tagttttagg
    15481 agcaggtttg attcccttag ctgtcatggg ttcaataatt atgggattga ttctaatatt
    15541 cttttcaaat aaaacaatat ctgaaactcc atatatattg atggtaaatt gtaataatga
    15601 agattcagaa gatatagcaa ctgataaaat taaaaaagta tttactaaat atcaaataaa
    15661 atcaaaaagt gttacaccag aaaaaggaat agaattagtg tttgaagtaa gaatgaaaga
    15721 tggagaaaca agtcttataa atgacttgag tcaagtagat ggagttacta atgcagttct
    15781 tgtaagttat aatggtgact atgtagcata gagaggagta atcttttatg aaagataaaa
    15841 aatttaccct tcttatctcg attatgatta tatttttatg tgctgtagtt ggagtttata
    15901 gtacatctag caacaaaagt gttgatttat atagtgatgt atatattgaa aaatatttta
    15961 acagagacaa ggttatggaa gttaatatag agatagatga aagtgacttg aaggatatga
    16021 atgaaaatgc tataaaagaa gaatttaagg ttgcaaaagt aactgtagat ggagatacat
    16081 atggaaacgt aggtataaga actaaaggaa attcaagtct tatatctgta gcaaatagtg
    16141 atagtgatag atacagctat aagattaatt ttgataagta taatactagt caaagtatgg
    16201 aagggcttac tcaattaaat cttaataact gttactctga cccatcttat atgagagagt
    16261 ttttaacata tagtatttgc gaggaaatgg gattagcgac tccagaattt gcatatgcta
    16321 aagtctctat aaatggcgaa tatcatggtt tgtatttggc agtagaagga ttaaaagagt
    16381 cttatcttga aaataatttt ggtaatgtaa ctggagactt atataagtca gatgaaggaa
    16441 gctcgttgca atataaagga gatgacccag aaagttactc aaacttaatc gttgaaagtg
    16501 ataaaaagac agctgattgg tctaaaatca caaaactatt aaaatctttg gatacaggtg
    16561 aagatattga aaaatatctt gatgtagatt ctgtccttaa aaatatagca ataaatacag
    16621 ctttattaaa ccttgatagc tatcaaggga gttttgccca taactattat ttatatgagc
    16681 aagatggagt attttctatg ttaccatggg attttaatat gtcatttggt ggatttagtg
    16741 gttttggtgg aggtagtcaa tctatagcaa ttgatgaacc tacgacaggt aatttagaag
    16801 acagacctct catatcctcg ttattaaaaa atgagacata caaaacaaaa taccataaat
    16861 atctggaaga gatagtaaca aaatacctag attcagacta tttagagaat atgacaacaa
    16921 aattgcatga catgatagca tcatatgtaa aagaagaccc aacagcattt tatacttatg
    16981 aagaatttga aaaaaatata acatcttcaa ttgaagattc tagtgataat aagggatttg
    17041 gtaataaagg gtttgacaac aataactcta ataacagtga ttctaataat aattctaata
    17101 gtgaaaataa gcgctctgga aatcaaagtg atgaaaaaga agttaatgct gaattaacat
    17161 caagcgtagt caaagctaat acagataatg aaactaaaaa taaaactaca aatgatagtg
    17221 aaagtaagaa taatacagat aaagataaaa gtggaaatga taataatcaa aagctagaag
    17281 gtcctatggg taaaggaggt aagtcaatac caggggtttt ggaagttgca gaagatatga
    17341 gtaaaactat aaaatctcaa ttaagtggag aaacttcttc gacaaagcaa aactctggtg
    17401 atgaaagttc aagtggaatt aaaggtagtg aaaagtttga tgaggatatg agtggtatgc
    17461 cagaaccacc tgagggaatg gatggtaaaa tgccaccagg aatgggtaat atggataagg
    17521 gagatatgaa tggtaaaaat ggcaatatga atatggatag aaatcaagat aatccaatag
    17581 aagttggagg ttttggtaat agaggaggag gctctgtgag taaaacaaca acatacttca
    17641 aattaatttt aggtggagct tcaatgataa taatgtcgat tatgttagta ggtgtatcaa
    17701 gggtaaagag aagaagattt ataaagtcaa aataagatta aaattgaata taaataattt
    17761 taatactgtt aagtctaaat atttacttag cagtattttt tagaaaataa tgtgtttgat
    17821 taataatata aggtaataaa ttgataaaaa ttaaatacag catattaata atacataata
    17881 aagtaataaa aaactgttta agtataataa cttatattta gacagttttt ttcatttata
    17941 aataatataa atgaaattga aaacatttga aggatagaaa ttggttggat aaatgtataa
    18001 attacttcac caaaaaataa tgacaaaaac tgtaactaag ttgtaataaa atggtagtta
    18061 tttagcataa aataatgtat catagaagta tattataaaa ttaataaaat aagatttttg
    18121 taagaaaact gctggctttt gatatttaga gtgagtagtt aaattatgtt taggaggagt
    18181 agaatttgtt gcaaaaagta ttatggaaat ttttaaagct agtagtcggt ttatttatat
    18241 gttcagttgg tatagtattg acgataaatt gtaaccttgg attatctccc tgggatgtat
    18301 ttcatcaagg actttcaaat catataggaa taactatagg aactgcttct ataattgtag
    18361 gctctatagt agttattgct gatgtcgttc ttggagaaaa tgtaggatgg ggaactgttt
    18421 ttaacatgct actaattgga ttttttatgg atttactttt atatagtaat ttaattccag
    18481 aggctgataa tttatttgta ggaataatta tgttgatatt aggattggtt cttttgtctg
    18541 ttggaatggt attttatatg ggaagtggtt taggaagtgg acctagagat ggtttgatgg
    18601 ttgcaattca aaagaaaaca ggaaaatcac ttaaattaat aagaggtact atagaagttg
    18661 gagcattaat agtaggattt ttattaggtg gaaaagttgg tataggaact ataataagtg
    18721 catttggatt ggggtatttc acacaaatgg tatttggctt atttaaatta gattgtagta
    18781 agattaaaca tagatttata gtagatgata taaaatttat caaagtgtat atgagtggtg
    18841 agaaaaaagc tgctgttcaa aatatagtta agtaatttaa gaataaattc aacgaaatgt
    18901 taagtatttt aaattaacat tttgtttaga tagataaatt gaatattaaa agaatattaa
    18961 aatatgagga ttgctagaac actataaaat atagatttct agcaattttt tatttgttca
    19021 atattttttt agtactagaa gtcttattct ctatttaatg aatgaattaa tttataatta
    19081 gagatactaa actttataga tattaatata aacaccttta aactgtgtat tttccaaagc
    19141 ctttaaaatg cttgtattta ttctaaataa aaaaataaaa aaatgtcaaa aaaactcttg
    19201 tattatatcc aaattttata tataattacc tatgttgttt agaaatttta aactcaatgt
    19261 ttagtaaaca aaatgtttag taaaataaaa cagaaactag gaggtgcaac atggatatag
    19321 gtgaaaagat aaaaagatta agaacagaaa aacaactgac ccaggaagag ttagctaata
    19381 gatgtgaatt gtcaaaggga tttatttctc aattagaaaa taacttaaca tcaccatcca
    19441 tagctaccct tatagatata cttgaaatac taggtacaaa tttaagggaa ttttttaatg
    19501 aaatagatga tgaaagaatc agttttacaa aagaagatat gtttgaaact gaagatgaag
    19561 atttaaaata taaattaaag tggttaattc caaattcaca aaaaaatgaa atggagccaa
    19621 taataataac attgtatcca ggaggacagt ataaagaaga aaagccacat gaaggtgaag
    19681 aatttggata tgtattagca ggttcaatat atgtccatat aggcgaaaag aaaaataaag
    19741 taaaaaaagg agagagtttt tactttagac cgaaagcaaa tcactatata tcaaacgagg
    19801 gcaaaactac agcaaaagtg atttgggtaa gtacgccacc atcattttag aatagaggtg
    19861 tttaataatt ggtagaaaat ataatagaat taagggatat atctaaacat tatgaagaac
    19921 ttactgtttt agataatttc aatttagata taaagaaaaa tgagtttcta acattgcttg
    19981 gaccaagtgg atgtggaaaa actacaacat taaaaataat agcaggattt gagtatgctg
    20041 atgatggtaa agttttattt gaaggtaagg agataaataa tttgccacca tatgaaagac
    20101 aagtaaacac agtatttcaa aaatatgctt tatttccaca catggatgtt tatgaaaatg
    20161 tagcttttgg attaaaaatt aaaaagactc caaaagatgt aatagatgct aaagtaaaag
    20221 aggttttgaa acttgttgca ctagaaggtt ttgaaagacg acaagttgaa tcattgagtg
    20281 gaggacaaca acaaagaatt gcaatagcaa gagctctagt caatgaacca aaggtattat
    20341 tactagatga accacttgga gcacttgatt taaagttaag acaagagatg caaatagaat
    20401 taaagagaat ccaaaaaaaa ttaggaataa catttgtttt tgtaactcat gaccaagaag
    20461 aggctcttac tatgtcagat actattgttg taatgtataa gggcaaaatt caacaaatgg
    20521 gaacaccaca agatatatac aatgaaccta aaaattcatt tgtagctaag tttataggtg
    20581 aaagtaacat atttgatgga attatgatag aagattataa agttaatttc tgtaatagag
    20641 attttgagtg tgttgataaa ggattcgaaa aaaacgaaaa tatagaagta gtaataagac
    20701 cagaagatat aaaaatggta aagccagaag aaggaatgtt aaaggggaaa gttacatcta
    20761 cagtgtttaa aggagtgcat tacgagatag aattgaatga aaatggaaga ttgtggatac
    20821 ttcataatac taaaaatgct gaggttggga ctgaactagg catggatata tatccagaag
    20881 atatccatat aatgagaaaa gagaataact aagatgaaaa gaaaatcttt tttagcatat
    20941 ccatatgtag tttggagtgc gatatttgta ataattcctt taatattagt agtatttttt
    21001 agttttacaa aagaatcagg tggaggttat gcctttacac ttgagaatta taaagaagta
    21061 attgacccta tatatatgaa agtttttggg cgttctattc ttttagcagg aggagctaca
    21121 ttaatatgcc ttatagttgg ttatccagtg gcatatataa tttcaaaggc tcgtgtaagt
    21181 agaagaggtt cattaatatt attgtttatt cttcctatgt ggatgaactt tcttttaaga
    21241 acatatgcat gggttgctat attaggaaaa aatggacttt taaatacatt tttaggttgg
    21301 tttggaatac aaccattagc aattttgtat actaattttg ctatactttt aggtatggtg
    21361 tataactttt taccatttat ggttcttcca atatatacag cactatcaaa gatggataat
    21421 gatttgataa acgctgctca tgacttgggt gcaaataata tgacagtttt tagaaaaatt
    21481 atatttcctt tgagtttgcc aggtgtaatg tctggaataa ctatggtatt tatgccagca
    21541 gtcactactt ttgcaatatc aagactgtta ggtggaggta aaataatgct ggttggagat
    21601 ttgattgaac aacagtttac agttgttgga gattggaact ttggttcagc tatatcgata
    21661 tttatgatga tagtaatatt aatatctatg tctataatgt caaaatttgg agatgaatct
    21721 gacaaagaag gcggtgggtt actattttaa aattaaagaa aataacttct aatatatatt
    21781 tagcattagt attcttattt ttgtatgcac ccatatttgc tttggtacta ttttctttca
    21841 atgattcaaa atcaatggca agatggaatg gatttacatg gaagtggtat ggtcaattac
    21901 ttcaaaatga gagtataatg agtgctttat attatactat tgtaatagct atattagcgt
    21961 ctgtaatatc tacaatagta ggaactataa gtgctatagg aatacataag atgagaggta
    22021 agagtaagaa attaatacta aatgtaaact atcttcctat tttaaataca gagatagtta
    22081 cagcagtagc tcttatgagt ctgtttgtat ttgtaaaaat ggaatttgga tttacaacaa
    22141 tgctattggc acatataatg ttttgtttgc catacgttat actttcagtt ttgccaaaaa
    22201 tgaagcaatt acctgataat atagaagatg cagctatgga cttgggagca acacctatat
    22261 acgctcttag aaaagtaatt ttaccacaaa taaaaccagg tatagtttct ggatttttaa
    22321 ttgcatttac tatgtcaata gatgacttta taataagttt ctttaatgct ggaaatggtg
    22381 taagcaatct ttctatagaa atctatggaa tggctagaag aggtataaaa cctgaaataa
    22441 atgcattatc aacaataatg tttgcagtgg ttctaggttt acttttacta gctaataaaa
    22501 aagaatctat agtaaggggg attaaataat gattaagttt aaaaaagcaa tatcccttat
    22561 agctgtaggt atgatgacag ttactttatt tacaggatgt aataaagcaa ctgattctac
    22621 aaaagtttta aatgtatata atgttggaga ttatatagat gagtctctta tagataagtt
    22681 tgaaaaagaa acaggaatag atgttcaata ttcaacttat gatactaatg aaatgatgta
    22741 tcaaaaagta aagagtggta gtacacacta tgatttagta tttccttcag actatatggt
    22801 agagaaaatg aaaaatgaag gtcttttgga aaaattagat tttaagaata tacctaatat
    22861 gaaatattta gataagagtt ttttaaatcc tgtatacgac aaaactaatg aatatagtgt
    22921 tgcatatatg tggggaactc ttggaatatt gtacaataag aaagaagtta aagaccctat
    22981 ggatagctgg aatatacttt ggaatccaaa gtataaggga aatataatga tgtttgactc
    23041 tgttagagat actataggga taactcttaa aaaattagga tatagcatga atagtgtaaa
    23101 tccaaaagaa ataaatgaag ctaaaaatct tttaatgaaa caaaaggatt tagtattggc
    23161 ttatgtaaat gatgaaggta aggatagatt gcttggtgga gaagtggcaa tgggtatgct
    23221 gtattctgga gatgcagtta cactaatgga gcaaaatcct gaccttgatt atgctatacc
    23281 taaagaggga actaataaat gggtagatgc tatgtgtgta cctacaacag cacaaaataa
    23341 gaaagaagct gagctgttta taaacttttt attagaccca gagaatgcaa aagtaaatgc
    23401 tgagtacatt gggtattcaa cacctaatac aggagcacta aaattattag acccagaaat
    23461 aactcagaat cctgttgcat atccatctaa agaagtactt gataaatgtg aaacttttga
    23521 agatattggt gaaaatataa aattatatga caaggcttgg atagagttaa aatcaaaata
    23581 gggtcttgtt gttttaagta aatttactta ataaatactt aataaaactg ttctttttta
    23641 gaaaatttat tttctaatta ttgaacagtt ttattttttg tttaagttat attcatatgc
    23701 aatttaaata gtttattaat aaatgaaaac ttatttgtat aatgacttta ataataatta
    23761 gaaaaaatgg gcaacttaat agaataattg gaggtgtaaa tttataaaaa atgaatagga
    23821 taaataaaaa aatagattta ttaatattgg ctttgctcgt ttttatattt ttaattgttg
    23881 gaatagtaat actatcgatt aggacagaaa ataaattgaa tgtgttcata atgttagcaa
    23941 taattttttt tataataatg ttaacttatt tatcaaattc agtagtgggg ttgataacaa
    24001 gttcaataat tatatttatg tatacatcct atattttata taacaatatt actcacaata
    24061 tggatgttga atttatatca tatatgtgga taatagcaac accagtatct tcaattataa
    24121 tgggtaatct gaacaaaagc ataaatgaat tgcaaaatac aaataaaaaa ctatctgaac
    24181 agtataagga attagtgact attgatagtg aaactggact tagaaattta aagatttttt
    24241 ataatgatgt aaatatggag ataagtaaat ctattagaca taatactgat ttttctctta
    24301 tgatagtaaa attaccatac tacggaaacc tacagactat atttggtgaa aacaaaacta
    24361 ataaaatagt aaaatatatt ggttcaaata ttatagaatg tacaagaaat gaagatataa
    24421 tttatagttt acaaaaagat atgataggga tactaatgcc aaatacatct ttggaaggtt
    24481 caaaagttgt taaagacaga ataaagaaaa ggataaaaga attaaattta gatttaaaca
    24541 ataggggaaa atatgtaaat atagatgtca aaattgcatt tttacaatat aagagtagtt
    24601 ttggagatag tataaatttt aagaatatag ttgaagagga acttcaatat gatgtttaaa
    24661 atatttaata aaagtctatt aaaattagta gttgtattat caatagtact gacaatatca
    24721 aattttagct tatcttcata tgcatcagaa attacttcca gcacagataa ggtattaatc
    24781 atatatgatt ctaagaaaga aacagcttat aatagagata ttttaaatat tatgaggact
    24841 ctattgggaa gatttagttc agatatagag ctattaaaat tgagtaacta tgatggtgag
    24901 ataaataaaa attattacag tcatatattt attttaggaa tcaatgaaaa ctcatataat
    24961 aatgataaaa acactaaaaa cttgattagt tccttaaatt catataaagg aactatatgt
    25021 tggttaggat atggtataga aaatcttttg gaacataaaa aatacaattt agactatgta
    25081 ggaaaaacaa acaatatagt tagtgtaaat tatagaggta aatcatataa cttggatgaa
    25141 cattatgttt ttaacattgt agaatcaaaa gatacaagta ataaagtaat aggaagtatt
    25201 aatgatacct taaataagta tccatatata ataaatgata aaaatctttt ttatgtatca
    25261 aaattagatt tagatggagt tttattttat atattttgcg attcacttaa tgatattttt
    25321 aatattaaga cgtttgataa aggacgtata tttgtaagaa tagaagatgt acatgctttt
    25381 agagaaccaa aaaatcttgt agagatagcg gattatttaa gtagtaagaa tataccattt
    25441 acgattgcat taataccagc atatgtaaat cctaaaaatc ataaggtaat aactttatca
    25501 gaaagccctg aaattgtcaa agcaataaaa tatatgcaag ataaaggtgg aactgtgata
    25561 ttgcatggat atactcatca atacaagaaa gaagaagttt ctggagaagg gtatgaattt
    25621 tgggatggta aaaaagatga acccttaaaa gaaaatatga agatatttgt caaagataga
    25681 gttttgaatg gtcttagagt atgtatagag aatggaattt atcctcttgc atttgaagcg
    25741 ccacattatg caatggaatc agagggatat aaagaattaa aaaaatattt ttctacttat
    25801 atggggcaac atcaaaataa tgataaaaaa tttagcacaa atacatatcc ttatattatt
    25861 agggatacag aggagtttaa tatatttata cccgaaaatt taggatatat agacccagaa
    25921 gataagttta cttttcaaaa tataaaagaa aatttaaata aattatccat tgtaagaggt
    25981 tttagtggag ggttcttctt tcattcatat ttaaacatag agtatctaaa aaacacaata
    26041 gaatatttag aaaaacagaa tatagaattt atgaatttaa gagattttaa taattgggta
    26101 aaagttgatg aaatacaaat aagaaataat ggagatgaaa ttatagtcaa ctatgataag
    26161 gacttagatg aaataactaa aagtgatact agatttaaat ccatatccaa tattagtaaa
    26221 gttttaatat tcatagtatc tataagtgtt ttaatatttg tgattatatt tatatatttt
    26281 aagagaatag ataaaaagaa atttttaaaa taaatgattt tatattagaa tcaatatttt
    26341 aaaatatttt aggagaaatt tatgagagat ttaaatgtat cagagtattt gttcgtattt
    26401 agtctgttta gtatatggtc tttattgctt ataaatatta ttttagctat gggtggatat
    26461 atattttatt ttaaaaactt tgataaagaa ataaaagaaa ttgatgaata tcctatgata
    26521 tcaatacttg ttcctgctca taatgaagct aaagtgatag gtagaactgt ggagtctttg
    26581 ctattactca attatcctaa gagtaagatg gaacttattg ttataaatga caattcttct
    26641 gataatagta aagaaatttt agaaaatata aaggataggt acaacaatta taatttcact
    26701 ataataaata cagatagttt aacaggtgga aaaggaaagt ctaatgcatt aaatattgga
    26761 tatacgattt caaaaggaga ttttatagct gtttatgatg cagataacac accagataaa
    26821 aatgcactta gatatctagt acaaactata gtaatgaatg atgaattagg tgctgttatt
    26881 gggaaattta ggactcgaaa taaaaataaa aacctattaa ccaaatttat aaacatagaa
    26941 acattaagct ttcaatggat gtcacaagct ggtagatggc aactttttaa tctatgtaca
    27001 ataccaggaa ctaactttat attgaggaga agtatcatag aagaaattgg aggatgggat
    27061 agtaaagcaa ttgcagaaga tacagaaata agttttagga tatataaatt gggatacaag
    27121 ataaagcttg taccacaatc tataacatgg gaacaagagc cagaaactgt taaggtgtgg
    27181 ataaagcaac gtactagatg ggcaaaaggg aatatatatg tattaatgaa atatataaaa
    27241 aatatattta aacagggaag aaataagatt gtgtttgata tagcttactt tttttctgta
    27301 tattttctat ttttaacatc tgtaattata tccgatattt tatttgtttt aagtatatct
    27361 aaactagtag aaatttctat tccaattaac ttttttctaa tatggatact atcttatctt
    27421 ttatttatta tagaagtgag tataagcctt actatagaaa aaggtgaagc aacaattgaa
    27481 aatatattca tagtggcaat aatgtatttt acatactctc aactatggct gtttgtagct
    27541 ataaaaggaa tgatagagta tctaaaagat ataattttta aaagagaggt taaatggtat
    27601 aaaacagaaa gattttgatt catgtacagg aggaattaac atgaaaaaat ttattatatc
    27661 aattatatct ttagtattgt ttttttcaaa tatatcactt atatacaaag taaatgctga
    27721 tgagactaaa gttaaaaatt ataagtttga aagagatata actattgatg gtgttatagg
    27781 aagtaatagt actttttttg aagtaaataa aaattgggat attgaagaag ttttattgca
    27841 tcttaatttt agtaagagcc aaatattaaa tggagatgtt tcaagtttaa ctgtattgat
    27901 aaataatgta ccaataaaat ctattaaatt aaatgctaag acaaattata aaaatacatt
    27961 agaagtatta gttccaaaag attatataat tcaaggatat aatgaaataa aaataaaaac
    28021 atacaaaaca atatctgata aaatttgcca agatgattcc aatactggga actggatggt
    28081 tattcacaaa gaatcatata tatcaattag atataagcag aaaaaggtgg aaaactcaat
    28141 aaatgaatat ccgtatccat atgcagaaat tgaaaataat cataaattag atacaactat
    28201 agtagtacca gataatatga ctagaggaga gactacagca gtgtttaatt tggcatcagc
    28261 atttggaaaa ataacaaaaa atgatgattt aaagttagat gttaaattat attcagaaat
    28321 gaaaaattgg tcagatgata atattatata tattggtaaa cctgaaaata cagcagaaga
    28381 aattttggat attttaagta taaaggaaca aaccctatta tcttcaaact gtataatcaa
    28441 gcaagtagat tcaccataca ataagaataa gaagatgatg gtggtaattg gtagtaatga
    28501 agatgattta ataaaggcat caaatttatt aatagaaaat agactttcta accaagtttt
    28561 atcatcatca gtacttgtaa acaaagagac taatataaaa attaataggg aacaaaaatt
    28621 aaatttaggt catttaacat taaaagactt aggatattct gactttttgt tggaaggagc
    28681 atttaatcaa caagctttgt ttgatgtcaa aataccaacg ggtaaggtat tagatgatgg
    28741 ttcaaagatt atcttaaatt taagatattc tgacaattta gattttgaaa aatctttagt
    28801 tacagtgtct ataaatgatg ttattgtggg aagtaaaaaa ttggataggt cacattctaa
    28861 taatgataag ttagaattaa aaatacctaa agatatagat aataaaaact attatcaagt
    28921 taaattgaca tttaatttga gtataaaaaa ttcgaattgt gttactagag agagtaataa
    28981 tccttgggca tatgtatcaa ataattctta tttggcgtta tctatgaaag aaaatgaaac
    29041 cttatctttt gaaaattatc cgtatccatt tgttagagat gatgaattta atgatttaac
    29101 tgtgataatg ccagattatt cagggtcaca agctatgact tggatgttta gattaggtgt
    29161 tactttaggt gcgaatataa attcacataa tggaaatata aatgtaatta gaggaaaaga
    29221 atttagtgac aagtataagg atactaatat tgtagttttt ggagtgccac ataataattc
    29281 tgttataaag atgttaaata ataatttaaa tataaaattc gataaaaatt actccaattt
    29341 tatatcaaat gataagataa gctttattga tgattatgga aaaaatattt ctaccattca
    29401 attaataaaa tcaccatata ataatcaaaa aaatatcatg gtaattagtt caatgaatga
    29461 aaaaaactta tatttaggaa tggattattt gttgaataaa agtaaagtta atgatttaaa
    29521 aggagataca ttgataattg atgaatacgg agaggtagaa gatttagctt ataatttaaa
    29581 atctaagaaa gaagtaaaag attcaagttg gaatatgagt ataaataaga caactaaagt
    29641 atttttaatg atttctttta ttactataat tgtagtcatg atattatcaa tgctatatat
    29701 aaaaaaatat aaaagaagat aatatgataa atttattatt ttaaaagagg tatataattt
    29761 gaggaaatat atgaataaat ttaaattaaa aagaagtatt ttaatctcat taataatctt
    29821 aatttttata tttatagttt actttgtaag tattgagtta aaagatagga gtctagtaaa
    29881 taatcaatat aaaggtaaga ttaaatcggc caatttatct gtagattatg aaataaatca
    29941 agttatgaag gatatagata aattgggatt gaatacagta aatgtaccta taattataaa
    30001 tgtagagtcc attaattctg atattatgtc aatagataat aatagtaaag aaaaggcaat
    30061 taagttaata aaaaaattaa ataaaaaagg tatttcaaca atattagagg catatccatg
    30121 gattgaaaat ggaaaattgt atgagactga ctggaaccct ataaataaaa aaagattttt
    30181 ttatacttgg caaaatgcca tattaaatga acttataatt gatgtagcaa atccactgga
    30241 tgtaaatgtt ttaaatattg gttctaattt tgtacatttg gaagaatatc aacaaaattg
    30301 gggtgaaata atagattttg tacaatccaa atttgacggt tttgtaacgt acagaactaa
    30361 ttggtggtat acaaaaaaag atgatttaag tagtaagttg ttttatgaac aaaagctgaa
    30421 caataatttt tttgataagt tagattttat atctatagca gcatattttg agttaagtaa
    30481 taaacctgtt aatacagtgg atgaattaat ttctgcctta cactcatcta ctgtaaacaa
    30541 tagaggacaa aatataaaac aagaaatata taacctttat aaagctcata gaaaacctat
    30601 attttttgga gaattaggtt tttcaaatag agaaagtgca agttctcagc cgtggaatca
    30661 tactccttca aaagctgtaa atggcgaaga acaagcaagg tgttttgagg catataagaa
    30721 agtttttgaa aatgaagact ggataaatgg tttttctgtg ttttgtgtag gtaaaataga
    30781 tgacgaaaaa aatttttacc catcaaaaga gagtataaaa gttattaagt cttggtatga
    30841 ataattttga aagtgtagaa tttatataga ttaaatagat gattaggaga gacataaatg
    30901 aatgacatca aggttatgac tgtatttgga actagacctg aagctatcaa agtagcacct
    30961 ttaataaagg aacttgaaaa aagagagaat ataaaaagta ttgtttgcgt tacagctcaa
    31021 catagagaaa tgcttgacca agttatagaa acctttaata taaatgtaga ctatgatttg
    31081 gatataatgg aaaaaggaca aagcctgaat gatataacat gtaagatttt aaataaactt
    31141 cccttgattt taaacaagga aaatccaaat ataatattgg tacatggaga tacaaccaca
    31201 actctagcta caagtttgac tgcattttat aataaaactc ttgttggtca tatagaagct
    31261 gggcttagaa cctatgataa atattctcct tttccagagg agttaaatag acaacttaca
    31321 ggtattattg ctgatatgca ctttgctcct actaatttgg ctagaaaaaa cttgatttct
    31381 gaaggaaaac ctaataataa tatatttgta actggtaata ctgctattga tgctttaaag
    31441 atgacaataa aagaaaacta taatcatcct ataattgatg agattggtaa cgataggatg
    31501 attttactaa cctctcacag aagagaaaat ttgggtaaac ctatgaaaaa tatatttaga
    31561 gctataaagc gaatagtaga tgactttgaa gatgtacaga tagtatatcc catacattta
    31621 aatcctaaaa tacgaactat agctgatgag atatttggaa aatttcctga aaaaattcat
    31681 attatagagc ctttagatgt agctgatttt cataactttt taaataaatc ttatatgata
    31741 atgactgata gtggaggaat gcaggaagaa gctccatcat taggtaagcc agtccttgtg
    31801 ttgcgtgata aaacagaaag aacagaagga attgaagcaa agacacttaa attagtaggt
    31861 actaatgaag atagaatata taattcagtg agcgatttat taataaataa agataactat
    31921 gttcagatga gtaaagcatc taatccatat ggagatggaa atgcaagcaa atatatagtg
    31981 gatataataa ttaaaaaatt taattgcaaa tatttaaatt agataagacc taaaacatta
    32041 actaattgat ataagattta tgataatatt aaggaataca atttttaagg gggagtaata
    32101 tggctagaaa attaataaaa aatttgggta aaagtaaaag tgtaaagaga gtgaaacttt
    32161 tatttaagaa gatttttatt actgtattca tagtagcaag tatagttgct atttttaata
    32221 taacgaaata ttttgaggaa ttatacaaag taagggattt aaaaagtact aaaattgaat
    32281 actatatgga tgtggctgat gaagcaggag atggaaaggt ccaattaagt tggaaggcct
    32341 tacttgctat agacatggta atacatgatg aagatttaag taatataaaa aagaaagaca
    32401 cattggatat aggggaaaag tttatagtag aagataaaaa tgataaaggc gaaaaggtgt
    32461 ataaggtaaa aaagtttaat aaggtattaa gcgaattgaa atttgactct tctcaaaaaa
    32521 gtagagcaag aaaatacatg aaagatttag aatacacata ccttggaaat aaacaattag
    32581 atagtagtga tgaaaaaatt aaatttataa agaagttaga agactcagct ataagagaat
    32641 atattgatta tggaatattg ccctctataa caattggaca agctatatta gaatctggtt
    32701 ggggaaattc taaacttaca aaacagagta ataatttatt tggtataaaa gcagataaag
    32761 catggaaagg aaaaagtgta gaaatttcaa cttcagagca ttataatgaa aaaattgtag
    32821 ctagttttag gtcgtataat tcattacaag attctgtcaa agaccacagt ttatttttaa
    32881 ttaataataa aagatataga aaacatggat tgtttgaggc aaaagattat attagtcaag
    32941 ctcaatcatt agaaaatgca ggatatagta cagcagaaga taaaaaagga aatcgtatat
    33001 atgcagagct attaatagat gttattagga gttataattt gcaattgata gataataaag
    33061 ttgagacaaa ataattgtta actttatatg aggagataac aagataagat tcttttctac
    33121 aaaaagaata gaaaaattgt aaaaaaaact aaaaaaatgt attgacttgt tatttaaaag
    33181 gtgatattat tattactgta ctcgaaagag aacaaaa
//
LOCUS       DAEPHU010000044        32207 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 01A10CD0081
            SAMN05941466-rid12468953.denovo.044, whole genome shotgun sequence.
ACCESSION   DAEPHU010000044 DAEPHU010000000
VERSION     DAEPHU010000044.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941466
            Sequence Read Archive: SRR6291087
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 32207)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 32207)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068158.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 22:43:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,892
            CDSs (total)                      :: 3,805
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 87
            rRNAs                             :: 8, 1, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 55
            CDSs (without protein)            :: 55
            Pseudo Genes (ambiguous residues) :: 0 of 55
            Pseudo Genes (frameshifted)       :: 21 of 55
            Pseudo Genes (incomplete)         :: 28 of 55
            Pseudo Genes (internal stop)      :: 16 of 55
            Pseudo Genes (multiple problems)  :: 8 of 55
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..32207
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941466-rid12468953.denovo.044"
                     /strain="01A10CD0081"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            <1..328
                     /locus_tag="KR231_002202"
     CDS             <1..328
                     /locus_tag="KR231_002202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0004569.1"
                     /translation="LDKKTNKDIVLLVENELRDIVNVEYINQESSLDNHNKKQVNLEI
                     KVNGELANLLKLEGVMKKLRLNNKLEKIEINKLKVNNFDVQNIPNEYKQEKDNIVECK
                     MTVRVI"
     gene            581..1618
                     /locus_tag="KR231_002203"
     CDS             581..1618
                     /locus_tag="KR231_002203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SEC-C domain-containing protein"
                     /protein_id="HBH0004570.1"
                     /translation="MLGRNELCPCGSGKKYKKCCLNKDIVSERACRKTELSQKQYTDL
                     YSKLYDYSRQDKFKEECEKAKEMFYIMQNDSVNEKFERFFNTYLIQDHIMENKKVMTV
                     GFLEENGANLSQSEVSILKSMFESYVSIYEVKEVSAGKIVLKDCLSGNELCTEDVKLL
                     RSFKIGSCMIARIVDIEGTNILIDITISISNEVKDIILKDIMNLFNQYQDVYKDMKSF
                     LIYHTHILYKYIQQLLDPSIAEYLKRERDKNDTKVNSENELAEEECKVLDTLKENVEK
                     ENIDACIEFWNEYKKNHENIKGAENGWAAAVEYYVKKEAGQPITQVQISKKYDISSST
                     LGKRYKDLKIS"
     gene            1699..2064
                     /locus_tag="KR231_002204"
     CDS             1699..2064
                     /locus_tag="KR231_002204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0004571.1"
                     /translation="MSLSLGNAIAVSTNFIKSNPAVPVYNGEEIYAVIYHIEIGYNNG
                     VSPDTKQYIIIDYKEFDLSMDKKNELINIAKEYCKSKGIVENENLEINLLDNEEAENF
                     LEKVFNNMKVIRGLITKKG"
     gene            2069..2386
                     /locus_tag="KR231_002205"
     CDS             2069..2386
                     /locus_tag="KR231_002205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0004572.1"
                     /translation="MDYIGIENITPYENTYEFSVYEYDDEITLGSEKLYVCELRVVLI
                     KVNSLYVERLHKSVEAMVLVKNLKKDLDKTLVVNKIKNFVLDEIWVENLVKENIEVIF
                     VES"
     gene            2434..4038
                     /locus_tag="KR231_002206"
     CDS             2434..4038
                     /locus_tag="KR231_002206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0004573.1"
                     /translation="MLRVSNVKLGIDKDISLLKDVILKKLKIKEKNLVKYSIYKESID
                     ARKKGKMEFVYSVDVEVKDENKILNSKIKDVTKIKEIRYVNVPVGDKKLKNNPLVIGS
                     GPAGLFAGLLLAQMGYEPIILERGLDVDSRTKDISDFWTTRKLKNNSNVQFGEGGAGT
                     FSDGKLTTRIKDIRCRKVLEELVQFGAPDEILYSHKPHVGTDILKNVVKNIRNEIISL
                     GGQVRFNSKVTDIVVSNDSIQSVIINDTEKIDTDTIILAVGHSARDTYEMLYSRGIKI
                     VQKPFAIGARVEHPQDLINKAQYKDFYNHPRLGAADYRLIEHVSNGRTAYTFCMCPGG
                     SVIASASNDFEIVTNGMSEHARDKINANSAFLVNVTPEDFKSDNPLAGVHFQQKYEKL
                     AFELGGKNYNAPVQLVGDFINNKTSLNLGSVEPSYRPGYTLTNLSECLPSFVTETMRE
                     AFISLDKKLNGFAMYDAVLTGVETRSSSPIRIVRDENTLESVSIKNLYPCGEGAGYAG
                     GIVTAAVDGIKCAEKIIQKYTNNTKI"
     gene            4162..5790
                     /locus_tag="KR231_002207"
     CDS             4162..5790
                     /locus_tag="KR231_002207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Na/Pi cotransporter family protein"
                     /protein_id="HBH0004574.1"
                     /translation="MNIIISLMGGLGLFLYGMNLMGEGLQKSAGTKLKKIIKLLTSNL
                     FMGVLVGTGVTAVIQSSSATTVMVVGFVNAGIMTLKQAIGVIMGANIGTTVTAQLVSF
                     DLTGMAPVALGVGIILYLFGNKPRIKNIAEILIGFGILFTGMDFMKMAVEPLRDYQGF
                     TDLLVTFGRYPLLGLLLGFGITAIIQSSSASMGMLVALAAEGLVPLSAALPILYGQNI
                     GTCVTSLLSSIGANKNARRAAMMHLIFNVLGTVIFLIFLNKPVVSMVTSWDPSNVARQ
                     IANTHTLFNIISVLILLPFTSLIIKLAIKLVPDRAGDIDEDETKTIKYIDDRMIETPS
                     IALANTIKEALRMGEKAKESLNASMEALVEHSTEKIDKTYRRERLINDLQKAILNYLL
                     KLSKAALDDDSREVVDTLFNTVNDIERIGDHAKNIAELSQVAIDSNIYFSEEGQSELD
                     VMYNRVVSAYTYALESMRSDNVDLACKVIKIEEQVDIMEKSCRANHMYRLNNNLCSIE
                     NGVIYLDVISNLERISDHAVNIAQQVIAKRLGND"
     gene            6055..7404
                     /locus_tag="KR231_002208"
     CDS             6055..7404
                     /locus_tag="KR231_002208"
                     /EC_number="5.3.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate isomerase"
                     /protein_id="HBH0004575.1"
                     /translation="MGKINFDYSKATEFFCQNEIDVMQPYVDVAHDMLHNKTGLGNTF
                     LGWIDLPKNYDKEEFDRIKKSADKIKSDSDVLLVIGIGGSYLGSRAAIDMVSHSFRNG
                     LKKEQRKAPEVYFVGHNISSTYIMDLLDIIEGKDISVNVISKSGTTTEPALAFRIFKD
                     YLEKKYGKEEARKRIYATTDASKGALRQLATEEGYETFVIPDDVGGRFSVLTAVGLLP
                     IAAAGLDIDAMMKGANDAREAFQNPDLKSNDSYRYAVARTILHRKGKDVELLVNYEPQ
                     LHYVSEWWKQLYGESEGKENKGLFPASVDFSTDLHSMGQYIQDGKRLLFETVLNVENC
                     KRNITISSEEVDLDGLNYLAGKTVDFVNHKAFEGTLLAHTDGKVPNLVINIPQLDEYN
                     FGYLVYFFEKACGISGYLLGVNPFDQPGVEAYKKNMFALLGKPGYEKEKEELEKRLK"
     gene            7560..8639
                     /locus_tag="KR231_002209"
     CDS             7560..8639
                     /locus_tag="KR231_002209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435637.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trypsin-like peptidase domain-containing
                     protein"
                     /protein_id="HBH0004576.1"
                     /translation="MSRRKKGISLVILVAIISSILSSFLTIILVKDNLVSKSTGSSTP
                     IVVNDDGKSQNIYQAVAEKATPSVVGITTTSVDTSNMFAIPTETQGVGTGIIVDSNGY
                     ILTNSHVISDGQATSVNVLFNDGSTTSGKVVWFDQQLDLAIVKVDKTGLTPAEFADSD
                     KVKVGDISIAIGNPLGLDFQKTVTQGIISGLDRTIQTEKTNMTGLLQTDASINAGNSG
                     GPLLNQKGQVIGINTAKASQAEGLGFAIPINTAKSIVEEVIKNGKYEKVTLGIKGTDV
                     SNYEAATGTKLSTDKGVYVAEVISGSSAEKAGVKVGDIITKVGDTDITGMNDLNKKLY
                     TFSKGASTKITVNRGGKAVTINVNF"
     gene            8984..9892
                     /locus_tag="KR231_002210"
     CDS             8984..9892
                     /locus_tag="KR231_002210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycyl-radical enzyme activating protein"
                     /protein_id="HBH0004577.1"
                     /translation="MNPLVINLQKCSIHDGPGIRSTVFFKGCPLECVWCHNPESQTYT
                     KQVLYNEERCSKCEACINICPHKAIYKGETKICLDQDKCEFCETCLDYCVNNAREIVG
                     QEYSVRDLVKEIEKDRIFYEESGGGVTLSGGEVMAQDMDFICGVINMCKSKGIHVAID
                     TCGYAKSENYERVAKCADLFLYDIKLIDEDKHIKFTGKSNDLILKNVKILSELGANIN
                     IRIPLIVGVNVDDENLEVKKMIEFLKPLNIQAVSLLPYHNIGKHKYDKIYKKYEGEEL
                     QRPSEEKLEEIKRLFEASNFNTKIGG"
     gene            9897..12266
                     /locus_tag="KR231_002211"
     CDS             9897..12266
                     /locus_tag="KR231_002211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycyl radical protein"
                     /protein_id="HBH0004578.1"
                     /translation="MARGTFERTKKLREESINAEPHISIERAVLMTEAYKKYEGSVEI
                     PVLRALSFKHYIENRTLSINDGELIVGEKGDSPNGAPTYPEICCHTMEDLEVMHNRDI
                     INFSVSEEARKIHKEEIIPFWKKRQTRDKIINAMTPEWLAAYEAGMFTEFMEQRAPGH
                     TVCGDTIYKKGFLDLKKDIEARLKELDFLNDLDAYNKKADLEAMAIACDAMVILGKRY
                     AEKARQMAEEETDEAKKQDLLLIAETCDVVPAHKPETYHQAIQMYWFVHIGVTTELNI
                     WDAFTPGRLDQHLNPFYERDVENGILDRDRAQELLECLWVKFNNQPAPPKVGITLKES
                     STYTDFANINTGGINPDGQDGVNEVSYIILDVMDEMKLIQPSSNVQISKKTPQKFLKR
                     ACEISRKGWGQPAFYNTEAIVQELMEAGKTIEDARLGGTSGCVETGCFGKEAYVLTGY
                     MNIPKILELTLNNGYDPISKKQIGIETGDPRNFQSYEELFEAFKKQLHYMIDIKIEGN
                     AVIENICAKHMPCPLMSTIVDDCIEKGKDYQRGGARYNTRYIQGVGIGTITDSLTAIK
                     YNVFDKKKFDMDTLLKALDANFEGYEAILNLVSNKTPKYGNDDDYADEIMQEIFNAYY
                     NEVTGRPTVCGGEYRVDMLPTTCHIYFGEIMGASPNGRLCAKPVSEGISPEKGGDTNG
                     PTAVIKSCAKMDHIKTGGTLLNQRFAPSVVQGEKGLDNMANLVRAYFNMDGHHIQFNV
                     FDKNVLLEAQKNPQDYKDLIVRVAGYSDHFNNLSRTLQDEIIGRTEQTF"
     gene            12591..13394
                     /gene="proC"
                     /locus_tag="KR231_002212"
     CDS             12591..13394
                     /gene="proC"
                     /locus_tag="KR231_002212"
                     /EC_number="1.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrroline-5-carboxylate reductase"
                     /protein_id="HBH0004579.1"
                     /translation="MKTLGFIGSGNMGSAMIGGIVQSGLVKAEDITVSDLSQVALDKV
                     KEEFGVNTTTDSKVAVTNSDVVIVALKPNICEKALTPLKELIDANKIIVSIAAGKTIE
                     SLESFIGSDKKIVRVMPNTPALVGEGMSALCKNSNVTDEELNMIKALFESFGEAEIVS
                     EYLMDTVTGISGSSPAYVFMFIEAMADAAVLAGMPRQQAYKFASQAVMGSAKMVLETG
                     KHPGELKDMVCSPAGTTIEAVKVLEEEGFRAAVIKSIVACIDKSKDMSK"
     gene            13992..16748
                     /locus_tag="KR231_002213"
     CDS             13992..16748
                     /locus_tag="KR231_002213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HBH0004580.1"
                     /translation="MRDEILSFVNECVLFNSFDELKKESGIITEDIVKKFNLSRTQSS
                     RLLNDLVKSDNLIKINSRPVIFLPKNKINDVVGPTKKSIYENLDELKNECKLLKQETV
                     FNSIIGYDNSLKEVIEQIKTAVLYPNGGLTIMLTGESGVGKTFLAKIIYKYSVSSNVL
                     EKNSPYNVLNCAQYYNNLELLSSLLFGHVKGAYTGANESRAGLIEQSDGGVLFLDEVH
                     RLNSEGQEKLFTFMDTGTFSRIGENGVIRKARVRLIFATTESLSEFLQTFLRRIPINI
                     YVPNIEERGTIEKRKIVEHFIYEESKVLGLPIEITQITLNAILKIKFKGNIGECKNVI
                     KYACGRAYAKNQRRNGNIFVTLQDLPRNLYIENVDIFQFQSGKSKSIIFSPKQFSIEM
                     SNGRNKRNIIYQSFIKCLDYFDRLEKNEITKEKFSKKSSNLMIRLMDNLVFSNNDENN
                     NVLMELIISIMQDIFRNLEVNNNIKYDGNNVLAFSSYLYLKDESYQLSDEYKALENKL
                     LIYLKKESYKEYSIISKISTLITNRLDMYLNNVDTIIMIIFIKSTIIRMKFNQVNATI
                     IAHGYATASSMANVCNRMLGKNIFTAIDMPIDATIADVSKQMSRYLEGDRIKNGLIVL
                     FDMGSLNLIYEDLKNKINSPMLFIDQISTISALEVGNLLMQGKNIEEIAEIMDEETKP
                     NIQLYYPQKNKEYAIISSCFTGIGIAIKIQHLLSESLIGIVDVKIIPYDYDSLVSMGD
                     KEPVFEMYDVMAIVGTANPNVNGVDFILLEDIISGKGEDDVFRIFSRVVENEKIKNIN
                     DSIVKNFSLIRVIDSLTILDSKKIIERIEEGINAIENIQKKKLSNDKKISLYVHLSCM
                     IERLVRQTEIEEYTDMDLLIKNHHSEVKLIKNAFSVLEKSYSVQIPISEIGYIYNIIY
                     GLPQ"
     gene            16880..17359
                     /locus_tag="KR231_002214"
     CDS             16880..17359
                     /locus_tag="KR231_002214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBH0004581.1"
                     /translation="MVSLMRIDDRLIHGQVAYGWATSLGINVILVANDEAKNDQMKAM
                     SLNLAKPSNVTLYIRGVEESGEIVEKFASSKKSNVLVLVKNTKDALVVAKNSGGVLKE
                     INVGGLRYEEGKKKLTDLVAVDDDDINNFKQIGDLGIDIEFRMLPRDKKKQLSDLIK"
     gene            17375..17797
                     /locus_tag="KR231_002215"
     CDS             17375..17797
                     /locus_tag="KR231_002215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose transporter subunit IIA"
                     /protein_id="HBH0004582.1"
                     /translation="MKKFLIATHGELSRELVDTSKLIIGSLTNIEYFCMTTDKSADDA
                     EKEIRSILSNNKDSEEFVVLTDVFGGSVANICTNLLLQGFKFELLTGVNLPMLLSILL
                     LVEEDTKLIVKSGLEEAKNGIVYVNELLENQNKIKNVM"
     gene            17837..18628
                     /locus_tag="KR231_002216"
     CDS             17837..18628
                     /locus_tag="KR231_002216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBH0004583.1"
                     /translation="MLVQATMLAIIAGVGILDGRIFGQSMLDRPIVTGMLVGLVLGDI
                     KSGIMIGAQLELIWMGIAGIGAATPPDVVTGGVLGTAFAILSGNGAEVALAVAVPVAV
                     LAQSLGVLVRIINSYFSQKAVFYAKQADFKKVTIMMWLPVILFFLSTSVPTFLAIMIG
                     ADKVTALINAIPKVILDGLGVAGTLLPAVGFALLMDMLLSKKMSVFFFIGFLLASYGG
                     LDITAIALFGVCVAFVLNFYINNKENNQNPQLAINTLTEGEIDFE"
     gene            18621..19421
                     /locus_tag="KR231_002217"
     CDS             18621..19421
                     /locus_tag="KR231_002217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HBH0004584.1"
                     /translation="MNKLTKKELRSMFWRSFALQGAFNYERMQNLGYCYSMLPAIKKL
                     YNKKENQAKAIERHLEIFNTTTVVVPAILGITAAMEEENANNPEFDESSISAVKTALM
                     GPLAGIGDSLFWGTFRIIAAGVGVSLAKEGNIFGPLLFLLLYNIPAFALRIFGLKYGY
                     QVGVNSLERIQREGLMEKIMSMATTVGLFVVGGMVATMLSITTPLKFNLNGAEVILQD
                     ILDKIIPNMLPLTFAFVIYYMLKRKVSVTKLTIGTIVTGIALHAIGLL"
     gene            19469..20524
                     /locus_tag="KR231_002218"
     CDS             19469..20524
                     /locus_tag="KR231_002218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HBH0004585.1"
                     /translation="MTIQDYMLETPVRMREIISNADSLFNEVKRTNLKKIIITGSGTS
                     YHSGVQVQPYLQNLLDIDVVKMYPFMITEDTFKFDNENTLVVGVSQGGSSYSTYNAMK
                     LAEDKGCKIASMAGCKNALIDEISDYILTVNCGEEKSGAKTKGYYCTKLNLMLLGLQI
                     AREKGIISSEKYNEEINKILDAINRFEAVYKLSKQWIERNKEKLVNSKEIRIIGHSDI
                     YGDTLEAALKLLETMRIPVTGYEFEEFIHGIYNAINSDSTIFILDTGKEPRVTKMIDV
                     LSGWTENVFAIGRDVTENDKNLKIDITDNPYYQTFNFIVPIQLICGEIPTLRGVDPSV
                     PKDTRFHMKLGSKKLNK"
     gene            complement(20703..22649)
                     /gene="feoB"
                     /locus_tag="KR231_002219"
     CDS             complement(20703..22649)
                     /gene="feoB"
                     /locus_tag="KR231_002219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432373.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrous iron transport protein B"
                     /protein_id="HBH0004586.1"
                     /translation="MINVALLGNPNVGKTTVFNLLTGSNQYVGNWPGVTIEKKEGFLG
                     KEIKVVDLPGIYAMDTFSNEEKVSKSYLENEDVDVIVNVVDASNLSRNLYLTTQLMQF
                     NKPIVILLNMLDIAESKGVNIDAKKLSEELGVIVVPIIAKKKNGVDRIEEEIKGATQK
                     AFIYQKNFGSETETYKKLESILSRCTKTTYTQKKSISDKIDNIVLNPILAYPIFIGVL
                     FLLFKFTFDWVGGPLQEGFASLIEAYISAPVSDMLSNSSPWFKSLIVDGIIGGVGGTL
                     PFFPLIFTLFFGISLFEDSGYMSRTAFLMDKVMRKVGLSGKAFIPIVMGMGCSSPAIM
                     ATRTLESEKDRRVTALIAPLMTCGAKLPIYALFVAIFFPHNAALVTTSLYLVGIVMAI
                     VVALFLNKTAFKTEAEPFILELPEYRIPTIDALIKNTWNKSKGFLIRVVTVMFAMSVV
                     IWGLSSFNVFGYTEDINVSFLATLGHIISPIFKPLGFDDWRTSVAILSGLGAKEIVVN
                     SLNILYGNLTVVLPTIFNGVTAYTFLIFTALYTPCIAALATMKKEYGNKMMFTSFAYQ
                     FILAWIMAFIVKSIGGVLFMGNSIMEALIGGIIIVLALFILFNKFKSTKNGNVCSGCS
                     ICSGCPSANSCSSKEDSNKKNNAH"
     gene            complement(22667..22885)
                     /locus_tag="KR231_002220"
     CDS             complement(22667..22885)
                     /locus_tag="KR231_002220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417194.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrous iron transport protein A"
                     /protein_id="HBH0004587.1"
                     /translation="MTVYDLKIGEKGFINSIDGDIKLSKRLLALGCINSTEIEVKKVA
                     PLGDPIIIRFRGFDLAIRKSDAKNISLQ"
     gene            23091..23600
                     /locus_tag="KR231_002221"
     CDS             23091..23600
                     /locus_tag="KR231_002221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gx transporter family protein"
                     /protein_id="HBH0004588.1"
                     /translation="MKTRKMTFLGLMIGYSLALYVLETYIPNPLIVIFPGAKLGLSNI
                     ITLISLMLLGVKDTVIIVTIRVILSSIFAGPLSYLLFSIGGAYLSLLFMYLASKIKDL
                     SLIGISIIGAIGHNIGQLIVASLIIENILAIGYLPFMLMASLVTGMFVGLVSRYTIPK
                     LKHFYSKFY"
     gene            23678..23839
                     /locus_tag="KR231_002222"
     CDS             23678..23839
                     /locus_tag="KR231_002222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartyl-phosphate phosphatase Spo0E family
                     protein"
                     /protein_id="HBH0004589.1"
                     /translation="MANNELEALKNEIEAVREEINTYIEYPEIFQEELVESSKKIDIL
                     INKYMYLSK"
     gene            23990..24655
                     /locus_tag="KR231_002223"
     CDS             23990..24655
                     /locus_tag="KR231_002223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MgtC/SapB family protein"
                     /protein_id="HBH0004590.1"
                     /translation="MIDIGSKEIAIRLLLALIIGGIIGLEREKIRQFAGFRTHILIAI
                     GSCIVSITSIQLFFDYNLYTNADPARMPAQVLSGIGFLGAGAILKNKGGVKGLTTAAG
                     MWATACIGIAVGYGYYELAILGGLFVMIALFVLRIINTFLFSQEKNVLILKLSNLDSI
                     PFLYDKFEKNQLIVRNMEIECRNEEYWKVNFFVSYAKRIHLHDVMKEINMIEGVINVD
                     YLD"
     gene            24721..26505
                     /gene="pepF"
                     /locus_tag="KR231_002224"
     CDS             24721..26505
                     /gene="pepF"
                     /locus_tag="KR231_002224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453998.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligoendopeptidase F"
                     /protein_id="HBH0004591.1"
                     /translation="MGTDRSTIEEKYKWKIDKMYSSKEEIEKDISKVKNLIQEVKEYK
                     GKLSESKENLYKVLNISENASRIVQNLYVYTHMKQHEDTRINDNQGRATKTEMLSTDL
                     GVATSYIVPEILAIEENKLSEYLKDEKLSFYTKYIKDILRDKPHTLSEREEEILAATS
                     ELSTIPENVYDMLAYADMEFPEIEDEEGNKVKLSHSNYSLFIKSKNSRVRKDAFEGEF
                     STYEKYKNTFASTLYGGIKSEIFYAKTRKYNSAIEASLFSDDVSLDVYNNLISAIDKS
                     IPNLNKYVELKKKFLGLNEIHMYDLYVPLTDKFDMDIPYDKAQDIILEALKPLGEEYL
                     KVIKSAFDEGWIDVYDNEGKKGGAYSWGSYDSHPYILMSYKNDLNSLFTLVHELGHSV
                     HSHYSRTSQPFLYSDYKIFVAEVASTLNELLLINYLLENSKSKDETIYLLNYYLEQFR
                     TTVHRQTMFAEFEKIVHQRVESGEPLTADEFTNIYYKLNEKYYGKSAIVDKQIGIEWA
                     RIPHFYSNFYVYKYATGFSAASALSQQILSEGSTAVDRYINFLKSGGSEYPLEQLKSA
                     GVDMTKKESIEEALNVFAELVNKLEKEL"
     gene            26757..27599
                     /locus_tag="KR231_002225"
     CDS             26757..27599
                     /locus_tag="KR231_002225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter substrate-binding
                     protein"
                     /protein_id="HBH0004592.1"
                     /translation="MFKKKIGVLLASTMLVGALAVGCSSNSGGSGDSGDSSKVSVSGS
                     TSIGPLMETIGEKFQEKNQGVSVEVQQIGSSGGIKNAIEGTSEIGMSSRDLKDEEKSA
                     GLKETKIAIDGIALITNTANSVKNLTMDQVKGIYTGKITNWKEVGGNDAPIVIVSREE
                     GSGTRDGFQEIVGFDSEELTKDAQISDGSGNIKTTVEGNENAIGYISFGYVDEKVNSL
                     KINDVEATDANVIANKYPISRPFILVNKEDGLSEKGKALIDYILSDEGQALVSEKGFI
                     KVNQ"
     regulatory      27832..27915
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01786"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="cyclic di-GMP riboswitch class II; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="cyclic di-GMP"
                     /db_xref="RFAM:RF01786"
     gene            28495..29172
                     /locus_tag="KR231_002226"
     CDS             28495..29172
                     /locus_tag="KR231_002226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891739.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBH0004593.1"
                     /translation="MYNLLVVDDDVDILNINQIYFSNIGFNVYTSETAKDAMDIVESI
                     VLDCIILDISLPDIDGYKMCNDIKEKVNIPIIFLSNYEHEEEKVRGFLAGGDDYITKP
                     YSLKELELRIYARMRQYKNITSVPNVLKFSALVINVNSRKVTFDGESIDLTTMEFEIL
                     LFLAENKEQVFSKIEIYNQVWKMPDIGDQHTVQVHIAQMRKKINSLSREHQYIQTVWG
                     KGYKFVP"
     gene            29244..31259
                     /locus_tag="KR231_002227"
     CDS             29244..31259
                     /locus_tag="KR231_002227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893921.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine kinase"
                     /protein_id="HBH0004594.1"
                     /translation="MKKYNILKGTLIVLIVSLLAITGLNLLYKYDNKYTYKSIRASNG
                     ILTIDNDTFTKGKLVFLIDDWEFYNHKIFKPNDFTEQDIKPEYVFIGQYPDFSMRKGT
                     QSPYGNATYRMRIKNEGKDKLLSLELPEIFSASEVWINGEMVSKLGDVGTEKYRPKIK
                     NSVVSFIAKKNTEIIINVSNFSHYYSGLYYPPALGETKDISNMMFYRLLFYSIICFTT
                     FAIAIFSLSVWFLSNKSKIYLYFGCMCVFFAIHVSYPFVHLLGLPLVSFTYAVEDLSY
                     FMVVLCIICINGSISKIEENKVYRFLILPLGITMSIISIVIPIILLPYDMYFVNIYGK
                     LIDIYKYIVFIYILMSSLVSIYKKTCSEHISSYILVSVNTVFGISILFDAVTSNRFEP
                     IFTGWQTEYCGFVIVILFSVMMINRNRIIIKENEKLTRNLEHEVEVRTNELTTLLNER
                     KRFLADVAHDLKAPVSAIQAFIDLIKVGNIHVDEETRTYLYAINQKSNEVQNRVRSLQ
                     EFTSQDKSIGISEKICLNNFIKEIYENNLPDTQACGVNFETYVLEKKIYAKINKEMLT
                     RAFENLIYNALTFTPFDGKIILSMDKEDGFAIIKISDNGKGIPPENIPKVFDRFFTER
                     DNNEPKGQGLGLYIVKSIIREHGGEIFVDSELGKGTVFTIKLSLCFL"
     gene            31309..31989
                     /locus_tag="KR231_002228"
     CDS             31309..31989
                     /locus_tag="KR231_002228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBH0004595.1"
                     /translation="MQTKILIIDGDKDNCQKLKGFLEEKGISIDLAYNCEEAIGKIFS
                     NKYDLIFLEIILSDGDGWTLCKKIRNVTTCPIVYMTYINEDQSILNALNSGGDDYLIK
                     PLNLEILYAKVKAILRRMNSYVNNNENNTKLEEYNRTSGVIKLEDKIIKLTPTENKLL
                     NFFIENPEKTLTTKEIYEHVWMNEYLEDNYSVVVAVNGLRKKIEKDYKNPQKIITIRG
                     AGYYFNKE"
BASE COUNT        12806 a         3458 c         5704 g        10239 t
ORIGIN      
        1 tttagataaa aaaacaaata aagatatagt gttattagta gaaaatgaac tgagagatat
       61 tgtgaatgta gaatatatta atcaagaaag tagtttagat aatcacaata aaaaacaagt
      121 taatttagaa ataaaagtta atggagaact tgcaaatttg ttgaaacttg aaggtgtaat
      181 gaagaagtta agactaaata ataaacttga aaagatagaa attaataaat taaaagtcaa
      241 taattttgat gttcaaaata ttccaaatga atataaacaa gaaaaagaca atattgttga
      301 atgtaaaatg acagttagag tcatataaca aaaaagaata gataaagtaa aaaactatta
      361 tcaattaata aaattttata gaggaattag ttttacgata attcatttct acaagaggga
      421 ttgttgatga ttttatcgaa atcctaatta aagttaatat attgtaccaa aatataagtg
      481 aatttaatag aatatttact tatactatag attgattaat aaaaaaatgg tataataaca
      541 aattgtactt taatttaata ataagggagt ggaagtcata ttgttaggga gaaatgagct
      601 atgcccttgt ggaagtggca aaaaatacaa gaaatgttgt ttaaataaag atattgtttc
      661 agaaagagca tgcagaaaaa ctgaactttc acaaaaacaa tatacagatt tatattcaaa
      721 gttatatgat tattcaagac aggataagtt taaagaagaa tgtgaaaaag ctaaagaaat
      781 gttttatata atgcaaaatg atagtgtaaa tgaaaaattt gaaagatttt ttaatactta
      841 tttaatacaa gaccacataa tggaaaataa aaaggttatg acagttggtt ttcttgaaga
      901 aaatggtgca aacctaagtc aatcagaagt atcaatatta aaaagtatgt ttgaatcata
      961 cgtaagtatt tatgaggtaa aagaagtttc tgctggaaaa atagtattaa aggactgttt
     1021 aagtggaaat gaactttgta cagaagatgt aaaacttctg agaagtttta aaatcggaag
     1081 ttgtatgata gctagaatag ttgatattga aggaactaac atattgatag atataactat
     1141 aagtatatca aatgaggtta aagatataat tttaaaggat attatgaatc tattcaatca
     1201 atatcaagat gtatacaaag atatgaagtc gttcttaatt tatcatacac atatactata
     1261 caagtatata caacagcttt tagacccaag tatagctgaa tatttaaaga gagaaagaga
     1321 taaaaacgat acaaaagtta attcagaaaa tgaattagct gaagaagaat gtaaagtttt
     1381 agatactctt aaagaaaatg tagaaaaaga aaatatagat gcatgtatag agttttggaa
     1441 tgaatataag aaaaatcatg aaaatataaa aggagctgaa aatggttggg cagctgctgt
     1501 tgaatactat gttaaaaaag aagcaggaca acctataact caagttcaaa tatcaaagaa
     1561 atacgatata agctctagta cactaggaaa gagatacaag gatttaaaaa tatcttaatt
     1621 aattataaaa agctttaagt catagataaa gaatctatag tataatatat gtataatgtt
     1681 tagaaagagg tattaataat gagtcttagt ttaggaaatg caattgctgt atcaacgaac
     1741 tttataaaat ctaacccagc tgtacctgtg tacaatggag aagaaatata tgcagttatt
     1801 tatcatatag aaataggata taataatggt gtatcacctg ataccaaaca atatataata
     1861 atagactata aagagtttga tttatctatg gataaaaaaa atgaactaat aaatattgct
     1921 aaagagtact gtaaatctaa aggtattgta gaaaacgaaa accttgaaat aaacctttta
     1981 gacaatgaag aagcagagaa cttcttagaa aaggtgttta ataatatgaa ggttataaga
     2041 ggtcttataa ctaaaaaagg ataaataaat ggactatata ggaatagaaa atataacacc
     2101 ttatgaaaat acatatgaat ttagtgtata tgaatatgat gatgaaatca ccttaggtag
     2161 tgaaaagtta tatgtatgtg aattaagggt tgtattgatt aaagttaatt ctctgtatgt
     2221 tgaaagattg cataaatcag ttgaagcaat ggtcttagta aaaaacttga aaaaagattt
     2281 agataaaaca cttgttgtaa acaaaataaa gaattttgtg ctagatgaga tttgggtaga
     2341 aaatctagta aaagagaata tagaagttat atttgtagaa agctaggaat aaccctagct
     2401 tttttatatt acaatctaag agaggaaaac aatatgttaa gagtatctaa tgtaaaactt
     2461 ggaattgata aagatatatc tttattaaaa gatgttatac ttaagaagct aaaaataaaa
     2521 gaaaaaaact tagtcaaata tagtatatat aaagaatcta tagatgctag aaaaaaagga
     2581 aaaatggaat ttgtttattc tgtagatgta gaagttaaag atgaaaataa aatacttaac
     2641 tcaaaaataa aagatgtaac aaaaataaag gaaatcagat acgtaaatgt acctgtgggt
     2701 gataaaaaat taaagaataa tcctttggta attggtagtg gaccagctgg tttgtttgca
     2761 ggtctgcttt tagctcaaat gggttatgaa ccaatcatac ttgaaagagg tcttgatgta
     2821 gacagtagaa ccaaagatat aagtgatttt tggacaacta gaaaattaaa aaataattca
     2881 aacgttcaat ttggagaagg tggagcagga actttttcgg atggtaaact tacaactaga
     2941 ataaaagata tacgatgtag aaaagtatta gaagagttag ttcagtttgg ggcaccagat
     3001 gaaatattat actcacataa gccacatgtt ggaacagata tattaaaaaa tgtagttaaa
     3061 aatataagaa atgaaataat aagtttaggt ggtcaagtta gatttaattc aaaagtaaca
     3121 gatatagttg tatcaaatga ttctatacaa tctgtaataa taaatgatac tgaaaaaata
     3181 gatacagata caattatatt agctgttgga catagtgcaa gagatactta tgaaatgttg
     3241 tattcaagag gtataaaaat agttcaaaaa ccttttgcaa taggagctag agttgaacat
     3301 ccacaagatt taataaataa agcacagtac aaggattttt ataatcaccc taggttagga
     3361 gctgcagatt atagacttat agagcatgtt tcaaatggaa gaacagcata tactttttgt
     3421 atgtgtccag gaggtagtgt catagcatct gcatcaaatg attttgaaat agttacaaat
     3481 ggtatgagtg aacatgcaag agataaaata aatgcaaata gtgcattttt agtaaatgta
     3541 acgccagaag attttaagag tgataatcca ctagcaggtg ttcatttcca gcagaagtat
     3601 gaaaaattag cttttgaatt aggtggaaaa aattataatg caccagttca gcttgttgga
     3661 gattttataa acaataagac ttctttgaat ttaggaagtg ttgagccatc atatagacca
     3721 ggatatacac ttacaaattt aagtgaatgt ttgcctagct tcgtaacaga gactatgaga
     3781 gaagcgttta tatctcttga taaaaaattg aatgggtttg caatgtatga tgctgttttg
     3841 acgggagtag aaactaggtc atcatcacca ataagaatag tgagagatga aaatacttta
     3901 gaatcagtga gtattaagaa tctatatcca tgtggtgaag gtgctggata tgcaggtggt
     3961 atagttacag cagcagttga tggtataaaa tgtgcagaaa aaataataca aaaatacacc
     4021 aataatacaa aaatttaaca taaacttaat gattttttaa tatttaacat gaatttaaca
     4081 ttatcactcc tataatttga taaaatacaa taggttataa aatttttaga tacagtaatc
     4141 tctttacaag gaggaaataa tttgaacatt ataataagtc taatgggtgg attaggtctg
     4201 ttcttatatg gtatgaacct tatgggagaa ggtcttcaaa aatctgctgg gacaaagcta
     4261 aaaaagataa taaaactact tactagtaac ctatttatgg gagttttggt aggtacagga
     4321 gttacagcag taatacaaag ttcaagtgct actactgtaa tggttgttgg tttcgtaaat
     4381 gcaggaataa tgactttaaa acaggcaata ggagttataa tgggtgctaa tatagggact
     4441 actgttacag cccaattggt atctttcgac ttaactggta tggccccagt agcattaggt
     4501 gtaggtatta tactttattt atttggaaat aagcctagaa taaaaaatat agccgaaata
     4561 cttataggtt ttggtatatt atttacaggt atggatttta tgaagatggc agtggagcca
     4621 ctaagagact atcaaggatt tactgactta cttgttacat ttggtagata tccactactt
     4681 ggattattat tgggatttgg gattacagca ataatacaaa gttcaagtgc atctatgggt
     4741 atgttggttg cactggcagc agaaggtcta gtgccactat cagcagcact gccaattctt
     4801 tatggccaaa atattggtac atgtgtaact tcactgttat caagtattgg tgctaacaaa
     4861 aatgcacgaa gagcagctat gatgcatcta atcttcaatg ttttaggaac ggtgatattc
     4921 ttaatattct tgaataaacc agtagtaagc atggttacaa gttgggatcc aagcaatgtt
     4981 gcaagacaaa tagccaatac acatacattg tttaatataa tatctgtatt gatactttta
     5041 ccatttacaa gtcttattat aaaactagct ataaagcttg ttcctgatag agcaggtgat
     5101 atagatgaag atgaaactaa aactattaaa tatatagatg atagaatgat agaaactcct
     5161 tctatagctc ttgcaaatac gataaaagaa gcacttcgta tgggtgagaa ggcgaaggaa
     5221 agcctaaatg catctatgga agctttagta gaacattcaa ctgaaaaaat agataagaca
     5281 tatagacgag agagattaat caatgattta cagaaagcta ttttaaatta tttacttaaa
     5341 ctttcaaaag cagctttaga tgatgattca agagaagttg tggatacttt gtttaataca
     5401 gtcaatgata tagaaagaat tggtgaccac gctaaaaata tagctgaatt atcacaagtt
     5461 gcaatagatt caaatattta tttctcagaa gaaggacaat ctgaacttga tgttatgtat
     5521 aatagagttg tttcagcata tacttatgca ttagaatcaa tgaggagcga taatgttgat
     5581 ttagcttgca aggttataaa aattgaagaa caagttgata taatggagaa atcttgtaga
     5641 gctaatcaca tgtatagatt gaataataat ctatgtagta tagaaaatgg agttatttat
     5701 ttagatgtaa taagtaattt agagagaata tctgaccatg ctgtcaatat agcacaacaa
     5761 gttatagcga agagattagg aaatgattaa aaataattaa tttaaaataa tataaaattt
     5821 aaaatagagg ataaataaaa gagaaacttt aaatgatacg tttagagttt ctttttttgt
     5881 aaatttattt gactaaaatt tttaaattta tacatagtta tagtatttag aagaatcgat
     5941 ttcctgataa taaatgatga gatatgtatg attttgtggc aaacttttaa aaaaaacacc
     6001 tatattttgt gttataatct ctttaaaacg aatatgctga aaagagggat ttaaatggga
     6061 aaaataaatt ttgattatag taaagctaca gagttttttt gtcaaaacga aatagatgtc
     6121 atgcaaccat atgtagatgt tgcgcacgac atgttacata ataaaactgg tttaggaaat
     6181 acttttttag gatggataga ccttcctaaa aattatgata aagaagagtt tgacagaata
     6241 aaaaaatctg ctgataagat aaaatcagac tcagatgttc ttttggtaat aggtatagga
     6301 ggctcttatt taggttcgag agctgctata gatatggtaa gtcattcttt taggaatgga
     6361 cttaaaaaag agcaaagaaa ggctccagaa gtatattttg tagggcataa tataagctca
     6421 acatatatta tggatttatt agatataatt gaaggaaagg atatttctgt aaatgtaata
     6481 tctaaatcag gaactactac agaaccagct ctggctttta gaatatttaa agattactta
     6541 gagaaaaagt atggtaagga agaagcaaga aagagaattt atgcaacaac agatgcaagt
     6601 aaaggtgcac ttagacagtt agctacagaa gaaggatatg agacttttgt aataccagat
     6661 gatgtaggtg gtcgtttttc tgtattgaca gcagttggat tacttcctat tgctgctgct
     6721 ggacttgata ttgatgctat gatgaaaggc gcaaatgatg ctagagaagc atttcaaaat
     6781 cctgacttaa aaagtaatga tagttataga tatgctgttg ctagaacaat tttacataga
     6841 aaaggaaaag atgtagagtt attagtgaac tatgaacctc aactacatta tgtaagtgag
     6901 tggtggaaac agctttatgg agaaagtgaa ggaaaagaaa ataaaggttt attccctgct
     6961 tctgtagatt tctcaacaga tttacattct atgggtcaat acatacaaga tggaaaaagg
     7021 cttttatttg agacagtact taatgttgaa aactgtaaga gaaatataac tataagttca
     7081 gaggaagtag acttagatgg tttaaattat ttagcaggta agactgtaga ttttgtaaat
     7141 cataaagctt ttgaaggaac tctattggct catacagatg gaaaagtacc taatttagta
     7201 ataaatatac ctcaactaga tgagtataat tttggatatt tagtttattt ctttgagaag
     7261 gcttgtggaa taagtggata tttattggga gttaatccat ttgaccaacc aggagtagaa
     7321 gcttacaaga aaaatatgtt tgctttacta ggcaaaccag gttatgaaaa agaaaaggaa
     7381 gagctagaaa aaagacttaa ataattttaa atagttaagg tttaattaag attaaaataa
     7441 tataatgaaa tcatcaaaaa ggagtttact caaaatagat gatttcattt tttttatgaa
     7501 aaattgggaa aaatatattt tgataattta tattatatta agatagggag tggtatgaga
     7561 tgtcaagaag aaagaaaggg ataagtttag taatattagt tgctataata agttcaatac
     7621 ttagtagttt tctaacaata attttagtta aggacaattt agtaagcaaa tctacaggaa
     7681 gttctacgcc gatagttgta aatgatgatg gtaagagtca aaatatttat caagcagttg
     7741 cagaaaaagc tacgccatct gttgtaggta ttacaacaac tagtgttgat actagtaata
     7801 tgtttgcaat accaactgaa acacaaggtg taggaactgg aatcatagtt gattcaaatg
     7861 gatatatact tactaattct catgttatat cagatggtca agctacaagt gtaaatgtat
     7921 tattcaatga tggttcaaca acttcaggta aagtagtatg gtttgaccaa caacttgatt
     7981 tagctatagt taaggttgat aaaactggac taacaccagc agaatttgct gatagtgaca
     8041 aagtaaaagt tggagatata tcaatagcaa taggtaatcc tcttggatta gattttcaaa
     8101 aaacagttac tcaagggata ataagtggat tagatagaac tatacaaaca gaaaaaacta
     8161 atatgactgg tttattacaa actgatgcaa gtataaatgc aggaaatagt ggaggaccat
     8221 tgttaaatca aaaaggtcaa gtaattggta taaacacagc aaaagcttct caagcagaag
     8281 gattaggatt tgcaatacca atcaatacag ctaagagtat agttgaagaa gtaatcaaaa
     8341 atggaaaata tgaaaaagta actttaggca taaaaggtac agatgtatca aattatgaag
     8401 cagcaacagg tacaaaatta agtactgata aaggtgttta tgttgcagaa gtaatatctg
     8461 gttcatcagc agaaaaagct ggagtaaagg taggggatat tataactaaa gtaggagata
     8521 cagatataac aggtatgaat gatttaaata aaaagttgta tactttctca aaaggtgcta
     8581 gtacaaaaat aacagtaaat agaggcggaa aagcagtaac aataaatgtg aatttctaaa
     8641 tatgaccaaa aagatagaga ctacatggta aagtgtagtc tctattttta tttaattttt
     8701 atagtatata catctaaatt aattaaaatg atgtattgtt tatagtttat tgctatattt
     8761 tcttataaaa ataaatttaa taaatattta aatttaattt acaaaaacaa tataaatatc
     8821 ataataaaat aaaatttttt aatattacta aaaatatata gacaaaataa taacaaatat
     8881 agtattatgt aattgtagaa atgcttttca taggtatatt ctatgaagat gaattgcata
     8941 aaaatgaaaa aatggaatgg atattattta ggggtgaaaa atcatgaatc cattagttat
     9001 aaacttacaa aaatgtagca tacatgatgg accagggata agaagtacag tattttttaa
     9061 agggtgtcca cttgaatgtg tttggtgtca taatccagag agtcaaacat atacaaaaca
     9121 agttttgtat aatgaagaaa gatgttcaaa atgtgaagca tgtataaata tatgccctca
     9181 taaggcaatt tacaaaggtg aaacaaaaat atgcttagac caagataagt gtgagttttg
     9241 tgaaacttgc ttagactatt gtgtaaacaa tgcaagagag attgttggtc aagagtattc
     9301 tgtaagagat ttggttaaag agatagagaa ggatagaatt ttctatgaag aatcaggtgg
     9361 tggagtaact ctatcaggtg gagaagtaat ggctcaagat atggacttca tttgtggagt
     9421 aataaacatg tgcaaatcaa agggaatcca tgtagcaatt gatacatgtg gctatgcaaa
     9481 gtcagaaaat tatgaaagag ttgctaaatg tgcagatttg tttttatatg atattaagct
     9541 tattgatgaa gataagcaca taaaatttac aggaaaatca aatgacttaa tactgaaaaa
     9601 tgttaagatt ttaagtgaat taggggctaa cataaatata agaataccat taattgtagg
     9661 agtaaatgta gatgatgaaa atttagaggt taaaaaaatg atagagtttt taaagccttt
     9721 gaatatacaa gcagtaagtc ttcttccata tcataatatt ggtaaacaca agtatgataa
     9781 aatttataaa aagtatgaag gagaagaact acaaagacca tcagaagaaa aattagagga
     9841 aataaaaaga ctgtttgaag caagtaattt caatactaag attggagggt aataaaatgg
     9901 caagaggaac ttttgagaga actaaaaaat taagagaaga aagtattaat gcagaaccac
     9961 acatatctat tgaaagagca gtacttatga cagaagctta taaaaaatat gagggaagtg
    10021 tagagattcc tgtacttcgt gctttatcat ttaagcatta tattgagaat agaactctta
    10081 gcataaatga tggagaatta atagtaggtg aaaaaggtga ttctcctaat ggagcaccaa
    10141 catatccaga aatttgttgt catacaatgg aagatttaga agtaatgcac aatagagata
    10201 taataaattt tagcgtatca gaagaagcta gaaaaataca taaagaagaa ataattcctt
    10261 tttggaaaaa gagacaaaca agagataaga taataaatgc aatgacacct gagtggttag
    10321 cagcatatga agcaggtatg tttacagagt ttatggaaca aagagcccca ggacatacag
    10381 tttgtggaga tacaatatat aaaaaaggat ttttagattt aaagaaagac atagaagcaa
    10441 gattaaaaga gctagatttt cttaatgatt tagatgcata taataaaaaa gcagatttag
    10501 aagctatggc aatagcttgt gatgcaatgg ttatattagg taaaagatat gctgagaaag
    10561 caagacaaat ggcagaagaa gaaacagatg aagctaagaa acaagattta ttactaattg
    10621 ctgaaacttg tgatgttgta ccagctcaca aaccagaaac ttatcatcaa gctatacaaa
    10681 tgtattggtt tgttcatata ggggttacta ctgaacttaa tatatgggat gcttttactc
    10741 caggaagact tgaccaacat ctaaatcctt tctatgaaag agatgtagaa aatggaatac
    10801 tagatagaga tagagcacaa gaattacttg aatgtttatg ggttaaattt aacaatcagc
    10861 cagcaccacc aaaagttggt ataacattaa aagaaagtag cacatataca gattttgcaa
    10921 atataaacac tggtggaata aatccagatg gtcaagatgg tgttaatgaa gttagttata
    10981 taatacttga tgttatggat gaaatgaaat tgatacaacc tagttcaaat gttcaaataa
    11041 gtaaaaagac tcctcaaaaa ttcttaaaga gagcttgtga aatatcaaga aaaggatggg
    11101 gtcaaccagc attttataat actgaagcaa tagttcaaga gcttatggaa gctggaaaaa
    11161 ctatagaaga tgcaagactt ggtggaacca gtggttgtgt tgaaactgga tgttttggta
    11221 aagaagcata tgttctaact ggatatatga acattccaaa aatacttgaa ttaacattaa
    11281 ataatggata tgacccaatt agtaaaaaac aaataggtat tgaaactgga gaccctagaa
    11341 atttccaatc ttatgaggaa ctatttgaag catttaaaaa gcaattacat tatatgattg
    11401 acataaaaat agaaggaaat gctgtgatag aaaatatatg tgcaaaacac atgccttgtc
    11461 cacttatgtc tacaatagtt gatgattgta tagaaaaagg caaggattac caaagaggtg
    11521 gagcaagata caacactaga tatatacaag gtgttggtat aggaactata acagatagtt
    11581 taacagcaat aaaatataat gtatttgata agaaaaaatt cgatatggat acattgctta
    11641 aagcacttga tgctaatttt gaaggatatg aagctatact taatttagtt tcaaataaga
    11701 ctcctaaata tggaaatgat gatgattatg ctgatgaaat aatgcaagag atattcaatg
    11761 catattacaa tgaggtaact ggtagaccaa ctgtttgtgg tggagaatac agagtagata
    11821 tgttaccaac aacttgtcat atatactttg gagaaattat gggagcaagt ccaaatggta
    11881 gactttgtgc aaaaccagtt tcagagggaa tttcacctga aaaaggtgga gatactaatg
    11941 gacctacagc agttataaaa tcttgtgcta agatggacca cataaaaact ggtggaacat
    12001 tattaaatca aagatttgca ccatcagtag ttcaaggaga aaaagggtta gataatatgg
    12061 ctaatctagt aagagcatac tttaatatgg atggtcatca tatacaattt aatgtatttg
    12121 ataaaaatgt actgttagag gctcaaaaga atcctcagga ttataaagac ttaatagtta
    12181 gagttgcagg atatagtgac catttcaata atttaagtag aacactacaa gatgagataa
    12241 taggaagaac tgagcaaaca ttctaggttt gcttgtaaat aaaacttctt actatataaa
    12301 atcgtaactg atataataaa gtataaatgg tttgattcca tttttaaaat tttagattaa
    12361 ttatgagcta actttctaaa taggaagtta gctcgttaag tttaatgaaa aaatcgttaa
    12421 atttatattt agtaaatcat acacatatta gtaagtaata catacaaaag aataatttat
    12481 tatagttata ataaggttat attttataaa aataagataa ttttaagcag ttaaaataaa
    12541 gtcaatttag ctactttaaa ataaaactaa tagaaaaaag gagatttgat atgaaaactt
    12601 taggatttat tggttcaggg aatatgggaa gtgcaatgat aggtggcata gtacagtcag
    12661 gattagtaaa ggcagaagat ataactgtat cagatttaag ccaagttgcc ttagataaag
    12721 taaaagaaga atttggagta aatactacaa ctgattcaaa ggtagctgtt acaaattctg
    12781 atgtggtaat agtagcactt aaacctaata tatgcgaaaa ggctttaact ccacttaaag
    12841 aattaataga tgcaaataaa ataatagtat ctatagcagc aggtaaaact atagaaagtc
    12901 tggaaagttt tataggttca gataaaaaaa tagtaagagt aatgcctaat actccagccc
    12961 ttgttggcga aggaatgtca gctctttgta aaaatagtaa tgtaacagat gaagagttaa
    13021 atatgattaa ggctctgttt gaatcttttg gtgaggcaga aatagtatca gaatatttaa
    13081 tggatacagt tacaggtatt agtggttctt ctcctgcata tgtatttatg tttatagaag
    13141 ctatggcaga tgcagcagta ttagctggaa tgccaagaca acaagcttat aaatttgcat
    13201 ctcaagcagt aatggggtca gctaagatgg ttcttgaaac tggaaaacat ccaggtgaat
    13261 taaaagatat ggtttgttct ccagcaggaa ctactataga agctgttaag gtattagaag
    13321 aagaaggctt tagagcagca gttataaaat ctattgttgc ttgtatagat aagtctaaag
    13381 atatgagtaa ataacagatg taattaagtt tactatatgg tttcttgaat tgttttttta
    13441 gtgcttattt atatctatac ataaatgtat ttggtataag taaaataaga gtaatttact
    13501 ataaaaagga atttaatgat tgagtgagaa tttattactt aaatattaat aattaaatag
    13561 atatattttt aactatattt gagatatatc attgtgaaaa aataaaattt ataagtatta
    13621 ttgtgaggtt ataagtagat ttatttaaaa ataaatttat ttatagcctt tttaaatttg
    13681 aaataatatt cataaggtaa taaaagttac aaatattttc ttcgctaata agttttaaaa
    13741 tacctataat gttttacttt ttattataat aaatacaata aatatattct tatataaatt
    13801 ctatgtcaga tatatggaaa gataagaacc ttgagattat gttaaaaaat ctagatttta
    13861 tacttataaa aagtttgatt ttacaacctt acaaaagaga atcaagatag gaatataatt
    13921 atctttttca taaatatata aatgatatac taatattata gtattattga tatttgtatt
    13981 ggaggttgaa catgagggat gaaattttaa gttttgtaaa tgaatgtgta ttatttaaca
    14041 gctttgatga acttaaaaaa gaaagtggca taataacaga agatatagta aaaaagttta
    14101 atttaagtag aactcaatca agtagattat taaatgattt agtaaaatct gataatctta
    14161 taaagataaa cagtagacct gttatttttt tacctaaaaa taaaataaat gatgtagtag
    14221 gacctacaaa aaaaagtatt tatgaaaatt tagatgaact taaaaatgag tgtaaattat
    14281 taaagcaaga gactgtgttt aatagtatca taggatatga taatagctta aaagaagtaa
    14341 tcgaacaaat aaaaaccgct gtactttatc caaatggcgg acttacaata atgctgacag
    14401 gtgaaagtgg agtaggaaaa acttttttag ccaagataat atacaaatat agtgtaagca
    14461 gtaatgtatt agaaaaaaat tctccataca atgtgttaaa ctgtgcgcag tattataata
    14521 atttggagtt attgtctagt ctattatttg ggcatgtaaa aggagcatat actggagcaa
    14581 atgaatctag agcaggtcta atagaacaat cagatggtgg tgttttattt ttagatgaag
    14641 tccatagatt aaatagtgaa ggtcaggaaa agttatttac atttatggat acaggtacgt
    14701 tttctaggat tggagagaat ggagtaatta gaaaagctag ggtaagatta atatttgcta
    14761 caacagaaag tctatctgaa tttttacaaa cctttttaag aagaataccc ataaatattt
    14821 atgttcccaa tatagaagaa agagggacta ttgaaaaaag aaagattgta gaacatttta
    14881 tttatgaaga aagtaaggta cttggtttgc ctatagagat aactcaaatt acattaaatg
    14941 cgattttaaa gataaaattc aaggggaata taggtgaatg taaaaatgta ataaaatatg
    15001 catgtggacg agcttatgca aaaaatcaaa gaagaaatgg aaatattttt gttactcttc
    15061 aagaccttcc tagaaatctt tatatagaaa atgtagatat atttcaattc caaagtggta
    15121 aaagcaaaag cattatcttt tctcctaaac aatttagtat tgaaatgtca aatggaagaa
    15181 ataaaagaaa tataatctat caaagtttca taaaatgttt agattacttt gatagactag
    15241 aaaaaaatga aataacaaag gaaaaattta gtaaaaagag ttctaatcta atgattagac
    15301 taatggacaa tttagtcttt tcaaataatg atgaaaataa taacgtactt atggagctta
    15361 taatatcgat aatgcaggat atatttagaa atttagaagt taataacaat ataaaatatg
    15421 atgggaataa tgtattggca ttttcgtctt atctttattt gaaggacgaa tcttatcaat
    15481 tgtctgatga gtataaagct ttagaaaata aattactaat atatttaaaa aaagagagtt
    15541 acaaagaata ctctataata agtaaaatat caacattaat aacgaataga ttggatatgt
    15601 atcttaataa tgtagataca atcataatga ttatatttat taaatcaaca attataagaa
    15661 tgaaatttaa tcaagttaat gcgactatta tagcacatgg atatgctact gccagtagta
    15721 tggcgaatgt atgtaatcgg atgttgggta aaaatatatt tacagctatt gatatgccta
    15781 tagatgctac tattgctgat gtatcaaaac aaatgtctag atatctagag ggagatagga
    15841 taaagaatgg tttaattgta ttatttgata tgggctctct taatcttata tatgaagatt
    15901 taaagaataa gataaatagc ccaatgttat ttatagacca aatatccact atttctgcac
    15961 tagaagtagg aaatttatta atgcaaggta aaaacattga agagattgca gaaattatgg
    16021 atgaagaaac taaacctaat atacaattgt attatcctca aaaaaataaa gaatatgcta
    16081 taatatcatc ttgttttaca gggataggta ttgctataaa aatccaacat ctactttccg
    16141 aaagtttaat tggaatagtt gatgtcaaaa taatacctta tgattatgat agtcttgttt
    16201 ctatgggaga taaagaacca gtttttgaaa tgtatgatgt gatggctata gtaggaactg
    16261 ccaatccaaa tgtgaatggg gtagatttta tattattaga ggatataata tcaggaaaag
    16321 gagaagatga tgtttttaga atatttagca gagtagtaga aaatgaaaaa ataaagaaca
    16381 taaatgattc tattgtaaag aatttttcat taattagagt aatagatagt ctaactattt
    16441 tagattcaaa aaagataata gagagaatag aagaaggaat taatgctata gaaaatattc
    16501 aaaagaaaaa actttcaaat gataaaaaga tttctttata tgttcactta agttgtatga
    16561 ttgaaagatt agttagacaa actgaaattg aagagtatac tgatatggat ttgttaatca
    16621 aaaaccatca tagtgaagta aaactaataa aaaatgcatt tagtgtgcta gaaaagagtt
    16681 atagtgtgca aataccaatt tcagagatag gatatattta taatattatc tatggtctac
    16741 cacagtaaaa tacaagatta caaaataagt gaatgaaatt taaaaaagta tgccagtatt
    16801 tggcatactt tttgctttta tagataaatg agagtataaa caataaaaat tttaatgtat
    16861 gatggaggat ttggggaaaa tggtatcttt gatgagaatt gatgacagat tgatacatgg
    16921 tcaggttgca tatggatggg caacatcact aggtataaat gtaatactag ttgcaaatga
    16981 tgaagcaaaa aatgaccaaa tgaaagctat gtcactgaac ttagcgaaac ctagcaatgt
    17041 aactttatat ataagggggg tagaggaatc tggagaaata gtagaaaaat ttgcttcttc
    17101 aaagaaaagc aatgtattag tgttagtaaa aaataccaaa gatgctttag ttgtagctaa
    17161 aaattcagga ggagtattaa aagaaataaa tgtaggagga ttaagatatg aggaagggaa
    17221 gaagaaactt acagatttag ttgctgttga tgatgatgat ataaataact ttaaacaaat
    17281 aggtgattta gggattgata tagaatttag aatgttacct agagacaaaa agaaacaact
    17341 atcagattta ataaaataat ttaggagaaa gagaatgaaa aaatttctaa ttgcaacaca
    17401 tggagaattg tccagagagc ttgttgacac aagtaaatta ataattggtt cattaactaa
    17461 tattgagtat ttttgtatga caacggataa atcagcagat gatgctgaga aagaaattag
    17521 aagtatatta tcaaataata aagatagtga agaatttgtt gtcttaacag atgtgtttgg
    17581 tggaagtgtg gcaaacatat gtacaaactt acttttacaa gggttcaaat ttgaattatt
    17641 gacaggagta aatttaccaa tgcttttatc tatactttta ttagttgagg aggatacaaa
    17701 actaatagtt aaatcaggat tagaggaagc aaaaaatgga attgtttatg taaatgagtt
    17761 attagaaaat caaaacaaaa tcaaaaatgt aatgtaattt aatgtaaatt aaactaagtt
    17821 aaaatggagg ttcaatatgt tagtacaagc tactatgtta gctattatag caggagttgg
    17881 tatactagat gggcgtatat ttggtcaatc tatgcttgat aggccaatag ttacaggtat
    17941 gttagtagga ttagttttag gagacataaa atcaggaatt atgattggtg cacagcttga
    18001 attaatttgg atgggaattg caggaatagg tgcagctact cctccagatg tagtaacagg
    18061 aggtgtatta ggtacagctt ttgctatatt atcaggtaat ggtgcagaag ttgctttagc
    18121 agtagcagta ccagtagcag tcttagcaca atctcttgga gtattagtta gaataataaa
    18181 ttcgtacttt tctcaaaagg cagttttcta tgctaaacag gctgatttta agaaagttac
    18241 cataatgatg tggttgccag taatattatt ctttttaagt acatcagttc caaccttttt
    18301 agcaattatg attggtgctg ataaagttac agcattaata aatgcaatac ctaaagttat
    18361 attagacgga ttgggtgttg caggaacatt gttgccagca gtaggttttg cattgcttat
    18421 ggatatgtta ctttcaaaaa agatgtctgt atttttcttt atagggtttt tgttagcatc
    18481 ttatggtgga ttagatataa ctgctatagc tttatttgga gtatgtgtag catttgtact
    18541 aaacttttat atcaataaca aagaaaataa tcaaaatcct caattagcaa tcaatacttt
    18601 aacggaagga gagattgact ttgaataaat taacaaaaaa agaattaaga agtatgtttt
    18661 ggcgttcatt tgctcttcaa ggtgcattta attacgaaag aatgcaaaac ttaggttact
    18721 gttattcaat gttacctgca ataaagaagc tatacaataa gaaagaaaat caagcaaaag
    18781 caatagaaag gcatttggag atttttaata caacgacagt ggtagttcct gctatattag
    18841 gtataacagc cgctatggaa gaagagaatg ctaataatcc agaatttgat gaaagttcaa
    18901 ttagtgctgt taaaacagct cttatgggac ctcttgcagg aattggtgat tcattattct
    18961 ggggaacatt taggattata gcagcaggag taggagtatc acttgcaaaa gaaggtaata
    19021 tctttggacc actattattc ttactattat acaatatacc agcatttgcc cttagaatat
    19081 ttggacttaa gtatggttat caagtagggg taaattctct tgaaagaata caaagagagg
    19141 gacttatgga gaaaataatg tctatggcta caactgttgg tttattcgtt gtaggaggaa
    19201 tggttgcaac tatgttgagt ataactactc ctctgaaatt caacttaaat ggtgcagaag
    19261 taattttaca agatatacta gataaaataa tacctaatat gttaccttta acctttgcat
    19321 ttgtaatata ctacatgtta aagagaaagg taagtgtaac aaaattaact ataggcacta
    19381 tagtaacagg aatcgcttta catgctatag gtttgttata gaaattaatt ataatttatt
    19441 gaatatatag ataaggaagg tgtataaaat gacaatacaa gattatatgt tagaaacacc
    19501 agttagaatg agagaaatta tatctaatgc agatagctta tttaatgaag ttaagagaac
    19561 aaatctaaaa aagattataa taacaggttc aggtactagc tatcactcag gagtgcaggt
    19621 gcaaccatat ttacaaaatt tattagatat agatgttgtg aaaatgtatc catttatgat
    19681 aactgaagat acattcaagt ttgataatga aaatacccta gtagtaggtg tatctcaagg
    19741 tgggagtagt tattctacat acaacgctat gaagttagct gaagataagg gctgtaaaat
    19801 agcatctatg gcaggttgta agaatgcttt aatagatgag atttctgatt atatattaac
    19861 agtaaattgt ggtgaagaaa aatctggagc taaaacaaaa ggatattatt gtacaaagtt
    19921 aaacttaatg ttattaggtc ttcaaatagc tagagaaaaa ggtataatat ctagtgaaaa
    19981 gtacaatgag gaaataaata agatattaga cgcaattaat agatttgaag cagtgtataa
    20041 gctctctaaa caatggattg aaagaaacaa agaaaagtta gttaattcta aagaaataag
    20101 aataataggt cactctgata tatatggaga tacattagaa gcagcattaa aattattgga
    20161 aacaatgaga atacctgtaa ctgggtatga gtttgaagag tttatacatg gtatatataa
    20221 tgctataaat agtgattcta ctatatttat actagataca ggaaaagaac ctagagtaac
    20281 taagatgatt gatgtacttt ctggttggac ggaaaatgta tttgctatag gtagagatgt
    20341 tacagaaaat gataaaaatt taaagattga tatcacagat aatccttact atcaaacatt
    20401 taattttata gtacctatac aactaatatg tggggaaata cctacattaa gaggtgtaga
    20461 cccaagtgtt ccaaaagata ctaggttcca catgaagtta ggtagcaaga aactgaataa
    20521 gtaacaaaaa aagaggttgt ctcaaaatag agataagcct cttttttact agataagctc
    20581 ttttttactg ttgaaatgat gaaaatatat ttgattttat ataaaaaaga gtgcctcatg
    20641 aactaaaaag ttaattttga gacacccact tttatcttat tttaaactaa aatatttata
    20701 tattagtgtg cattattttt tttattgctg tcttccttac ttgagcaaga attagcactt
    20761 ggacatccag aacaaataga acatccacta cagacatttc cgttttttgt agacttgaat
    20821 ttattaaaca gaataaagag tgcaaggact ataattattc cacctatcaa agcttccatt
    20881 attgaattac ccataaatag tactccacct atacttttaa ctataaaagc cattatccat
    20941 gctagtataa attgatatgc aaatgatgta aacatcattt tattgccata ttcttttttc
    21001 atagttgcaa gtgcagctat acatggagta tataaagcag taaatatcaa gaatgtatat
    21061 gcagtaactc cattaaatat tgttggtaag acaacagtta gattaccata tagtatattt
    21121 aaagagttta ctacgatttc ttttgctcca agaccactta aaatagcaac tgaagttctc
    21181 caatcatcaa aaccaagagg tttgaatata ggagatataa tatgacctag agtagccaag
    21241 aagcttacat ttatatcttc tgtatatcca aaaacattga atgaagaaag tccccaaatt
    21301 acgactgaca ttgcaaacat gacagtaaca actcttatca agaaaccttt tgatttattc
    21361 caagtatttt taataagtgc atctatagta gggattctat attctggtaa ttctaatata
    21421 aatggttcag cctctgtttt aaaggctgtt ttatttaaga ataatgcaac tacaattgcc
    21481 ataactatac ccaccaaata cagtgatgta gttactaaag cagcattatg tggaaagaat
    21541 atagctacaa atagtgcata tataggtagc tttgctccac aagtcataag tggtgcaata
    21601 agagctgtaa ctcttctatc tttttcgctt tccaatgttc tagttgccat tatagctgga
    21661 gaagaacatc ccatacccat aactataggt ataaaagctt taccagatag accaaccttt
    21721 ctcataactt tatccattaa aaatgctgtt cttgacatgt atccactatc ttcaaacaac
    21781 gatataccaa agaataatgt aaatattaaa gggaagaatg gtaaagtacc accaacacct
    21841 ccaattattc catcaactat aagtgattta aaccatgggc tagagttaga taacatatca
    21901 ctaacaggtg cagaaatata agcctctata agactagcaa atccctcttg tagtggtcct
    21961 ccgacccagt caaaggtaaa tttaaataag aggaacaata caccaataaa tatcggatat
    22021 gctaatatag gattcaagac tatattgtct atcttatcac tgatagattt cttttgtgta
    22081 tatgtagttt ttgtacatct cgataaaatg gattctaatt ttttatatgt ttctgtttca
    22141 cttccaaagt ttttctgata tataaaagct ttttgcgtag ctcccttaat ctcttcttct
    22201 atcctatcaa caccattttt cttttttgct ataattggaa caacaattac tccaagttct
    22261 tcacttaatt ttttggcatc tatattaact cctttagatt ctgcaatgtc taacatatta
    22321 agcaatataa ctataggctt gttaaattgc ataagttgag ttgttaagta aaggtttctt
    22381 gataaattag aagcatcaac tacatttact attacatcaa catcttcatt ttctaaatat
    22441 gatttagaaa ccttttcttc atttgagaaa gtatccattg catatatacc aggtaaatcg
    22501 acaaccttta tctcttttcc aagaaatcct tctttttttt ctatagtaac accaggccag
    22561 ttacctacat attgatttga acctgtaagt agattaaaaa cagtagtttt accgacattt
    22621 gggtttccta ataatgctac attaatcacg ggtagctcct cctctattat tgtaaagaaa
    22681 tatttttagc atcagatttt ctaatcgcaa ggtcaaagcc tctaaatcta attataattg
    22741 ggtctccaag tggggcaacc tttttaactt ctatttcagt actatttata catccaagtg
    22801 caagcaatct tttagataat ttaatatctc catctatact attaataaat cctttttctc
    22861 ctatttttaa atcgtaaaca gtcattatta acacctccta atgaaattca ttatcattaa
    22921 aattgtaaca agtatgatac aaaaagtcaa gatttataga ggtaattgca cattgaaata
    22981 actaatattt attctaaata gattaaaaat attttagtct aaattaggtg tttttatata
    23041 ttttgtatta taatgtaaga tgatagataa aatttggagg agttaactta atgaaaacta
    23101 gaaaaatgac atttttaggt cttatgatag ggtatagttt agctttatat gtattagaga
    23161 catatatacc aaatcctctt atagttatat ttccaggggc aaaattgggt ttgagcaata
    23221 ttataacttt aatttcatta atgttgttag gtgtcaaaga tactgttata attgttacta
    23281 tcagggtaat tttgtcatca atatttgcag gccctttatc atatctacta tttagtatag
    23341 gaggagctta tctgagtctt ttatttatgt atttagcgag taaaataaaa gatttatcac
    23401 taatagggat aagcattata ggtgcaatag ggcataatat aggtcaatta atagttgcaa
    23461 gtttaatcat agaaaatata cttgctatag ggtacttacc atttatgtta atggcatcat
    23521 tagtaactgg tatgtttgta ggcttagtat ccaggtatac aatacctaaa ttaaagcatt
    23581 tttatagtaa gttttattga cataatattg acaaaatata atattgtttg ataaaatgta
    23641 tataaaaata tacaaatttg taatagtggt gattattatg gcgaacaatg aattagaagc
    23701 gttaaaaaat gagattgaag cagttaggga agagataaat acatacatag aatatccaga
    23761 aatatttcaa gaagagttag tagaatcaag taagaaaata gatatattaa taaataaata
    23821 catgtaccta agcaaatagc ccacagttgt gggttttttt gtatcaaaaa ttaacagatg
    23881 gctatatttt acatatatta ataataatat taagatataa aatagtattt ctgatgtgta
    23941 aattatctgt aggacataag ttgtaattaa gtcaggaggg ttttatatta tgattgatat
    24001 aggaagtaag gagatagcaa taaggttact attagcacta ataataggag gaataatagg
    24061 cttagagaga gaaaaaataa gacagtttgc aggatttagg acacatatac taattgcaat
    24121 aggttcttgt attgtttcaa taacttcgat tcaattattc tttgattata atttgtatac
    24181 aaatgctgac ccagcaagaa tgcctgctca agtattatct ggaattggtt ttttaggtgc
    24241 aggagcaatt ttaaaaaata aaggtggggt aaaagggctt actacagctg ctgggatgtg
    24301 ggcaactgca tgtattggta tagcagttgg atatggttat tatgaattgg caattctagg
    24361 tggattattt gtaatgatag cattatttgt gcttaggata atcaatacgt ttttatttag
    24421 ccaagaaaag aatgtattga tattaaaatt aagcaatttg gactctatac cttttttata
    24481 tgataaattt gaaaaaaatc aacttatcgt aagaaatatg gaaatagaat gtcgtaatga
    24541 agaatactgg aaggttaatt tttttgtatc ttatgctaag agaatacact tacacgatgt
    24601 tatgaaagaa ataaatatga tagaaggagt aataaatgta gattatttgg actaaaatat
    24661 atacaatata ttttgtaaag tgaataaaat ataaaacaaa ttaaaataga ggtgtatgat
    24721 atgggaactg atagaagtac aatagaagaa aagtacaaat ggaagataga taagatgtac
    24781 tccagtaaag aggaaattga aaaagacata agtaaagtaa aaaatcttat ccaagaagta
    24841 aaagaatata aagggaagct ttctgagagt aaggagaact tatataaagt attaaatatc
    24901 tctgaaaatg catctaggat tgttcaaaat ttatatgtat atactcatat gaaacaacat
    24961 gaagatacta gaattaatga taatcaagga agagccacta agacagaaat gttatctact
    25021 gatttaggtg tggctacttc ttatatagtt ccagaaatac tggcgataga agagaataag
    25081 ttaagtgaat acttaaaaga tgagaagcta tccttttata caaaatatat aaaggatata
    25141 ttgagagata aaccacatac tttgagtgaa cgagaggaag aaatacttgc agctacatca
    25201 gaattatcga caattccaga aaatgtatac gatatgttag catatgcaga tatggaattt
    25261 cctgagatag aagatgagga ggggaataag gttaagcttt ctcattcaaa ctactcttta
    25321 tttataaaaa gtaagaatag tagagttaga aaagacgctt ttgaaggtga attttcaaca
    25381 tatgagaaat ataaaaatac atttgcctca acgctttatg gtggaataaa atcagagata
    25441 ttttacgcaa aaactagaaa gtataattca gcaatagaag cgtctttatt ttcagatgat
    25501 gtaagtttag atgtttacaa taatcttata tcagctatag ataaaagtat tcctaatcta
    25561 aataaatatg ttgagcttaa aaagaaattt ttaggattga atgaaataca catgtatgat
    25621 ttgtatgttc ctttgacaga taaatttgac atggatatac catatgataa agcacaggat
    25681 atcatattag aggcacttaa acctttagga gaagaatact tgaaggtcat aaaaagtgct
    25741 tttgatgaag ggtggattga tgtatatgat aatgaaggta aaaaaggagg agcttattct
    25801 tggggaagtt atgattcaca tccttatata ttaatgagct ataaaaatga ccttaattct
    25861 ctattcactt tagttcatga attagggcac tctgttcaca gtcattattc aagaacaagt
    25921 caaccatttt tatattcgga ctataagata ttcgttgcag aagttgcatc tacattaaat
    25981 gaattacttc ttataaatta tttattagaa aattctaagt ctaaggatga aactatatac
    26041 ttattaaatt attatttaga acaatttaga actacagttc atagacaaac tatgtttgct
    26101 gaatttgaaa aaattgtaca tcaaagggta gagagtggag aaccacttac tgctgatgaa
    26161 tttactaata tatactacaa attaaatgaa aagtattacg gaaaatctgc aatagtagat
    26221 aaacaaatag gaatagaatg ggcgagaata cctcattttt attcaaactt ctatgtatat
    26281 aagtatgcca cagggttttc tgctgcaagt gctttaagtc aacagatact ttcagaagga
    26341 agtactgcag tagatagata tataaacttc ttaaaaagtg gagggtcaga atacccacta
    26401 gaacaattaa aatctgctgg tgtagatatg acgaaaaaag aatctataga ggaagcctta
    26461 aatgtatttg ctgaattagt taataaacta gaaaaagaat tataggatgt gataggttga
    26521 tagcttcaat gaagacttct gataatatga gttgtattat gtttatatct gcctaaagta
    26581 actttaaaaa gttaatctaa ttaagaataa atcatataaa attaagtttt tacatgtatt
    26641 taacaatatt tacatttact taaccctgct ctaatattca tttaacaaag aatctgtatt
    26701 attaaaatat agaaaaatga caacaaaaaa ttaaaatata agcgggggta agtaaaatgt
    26761 ttaaaaagaa aataggcgtt cttttagcta gtacaatgtt agttggagct ttagcagtag
    26821 gatgtagttc taactcagga ggttcaggtg attcaggaga ttcaagcaaa gtttctgttt
    26881 caggttcaac ttcaataggt cctcttatgg aaactatcgg agaaaagttt caagaaaaaa
    26941 atcaaggtgt tagtgtagaa gtacaacaga ttggttcttc tggaggtata aaaaatgcta
    27001 tagaaggaac atctgaaata ggaatgagtt caagagattt aaaagatgaa gaaaaaagtg
    27061 ctggattaaa ggaaactaaa atagcaatag atggtatagc attgataact aatactgcaa
    27121 actcagtaaa aaatctgaca atggaccaag ttaaaggtat atatacagga aagattacta
    27181 actggaaaga agtaggagga aatgatgcac caatagtaat agtatcaaga gaagaaggtt
    27241 caggaactag agatggattc caagaaattg tagggtttga ttcagaagaa ctaactaaag
    27301 atgcacaaat aagtgatggt tcaggaaata taaaaactac agttgaagga aatgaaaatg
    27361 ctataggata tatatcattt ggatatgttg atgagaaagt aaatagttta aaaataaatg
    27421 atgttgaagc aactgatgca aatgtaatag ctaataaata tccaatatca agaccattta
    27481 tattagttaa taaagaagat ggtttgtcag aaaaaggtaa agctttaata gattatatat
    27541 taagtgatga aggacaagca cttgtttcag aaaaaggatt tattaaagtt aatcaataac
    27601 aagagttata atataaagta aacatataat accctgtgag ataagctcat aaaaatgatg
    27661 ctttaacttg cagggtattg tctattattg aatgtagaaa tataaatatc tttagataaa
    27721 ataggtattt tagtatctta tctctaagaa tatggaaata ttgacaaaat aatattacaa
    27781 tgttagaata aaaaagaaat ttatgaaaat atataaaaga tttttaataa aaatatttta
    27841 gaaactgaga agtatatctt attattgggc atctagagat atatggagtt agtggtgcaa
    27901 ccggctatga atataatttt tatattgcat agtctttttt tgttttaaaa ttaacaaaaa
    27961 tgttgcaaaa tttgaaaata agagtattag tcgttaagat ttttattgat aggtaaaatt
    28021 ttggctttta aagtagccat ttgttggaaa agggaaattt ttttaaaaga ataatagtat
    28081 tataataaga aaataaagtt tttataaaca ttgagatgca gaatataaac cttttgtaac
    28141 aatatattta ccaaaataat acaatttatt ttatattata accatataaa tcatataaat
    28201 caatactcaa actagccaat agacaagttt ctagaaaaat aataaattta tacgtgaaaa
    28261 tgactttaag ctccattctc caacaatcgg agactttaat tagtatttaa taatgaatct
    28321 taatgtttaa tacaatattc aagaattatt caaaaatact taagtattat agtctagttt
    28381 gtaaagatat tataaaataa taataccagt tatatatgaa aataaaacat tataatttgt
    28441 aataactata aaacttggaa ttataattaa aatacctttg aatggagtgg tgtaatgtat
    28501 aatttactgg ttgtagatga tgatgttgat attttaaaca taaatcaaat ttatttttct
    28561 aatataggtt ttaatgtata tacatcagag actgctaaag atgctatgga tatagtagag
    28621 agtatagttt tagactgtat aattttggat atttcattgc cagatataga tggatataaa
    28681 atgtgcaatg atataaaaga aaaggttaac atacctataa tatttttatc taattatgag
    28741 catgaagaag aaaaagttcg gggattttta gctggggggg atgattatat aacaaaacct
    28801 tatagtttaa aagaacttga acttagaata tatgctcgta tgaggcagta caaaaatatt
    28861 acatcagttc ctaatgtgtt aaagttttca gcgttagtaa taaatgtaaa ttcaagaaaa
    28921 gtaacttttg atggagaaag tatagattta actactatgg aatttgaaat attattgttt
    28981 ctagctgaga acaaagaaca agtattttca aagatagaga tatataacca agtttggaaa
    29041 atgcctgata ttggagatca acatacagtg caggttcata ttgcacagat gagaaaaaaa
    29101 attaattctt taagcaggga gcatcaatac attcaaaccg tatggggaaa aggatataag
    29161 tttgtaccat aagtgagata ctgtaattaa taaatagttc ttgttttatt taatactact
    29221 atgaaagaga tgtggttgat acaatgaaaa agtataatat actaaaagga actctcattg
    29281 tattgatagt ctctctgctg gcaataacag gattaaatct tctgtataaa tatgataata
    29341 aatatacata taagtctatt agagcaagta atggaatttt aactatagat aatgatactt
    29401 tcactaaagg taaacttgtc tttttgatag atgactggga gttttataat cataaaatat
    29461 ttaaaccgaa tgattttaca gagcaagata taaaaccaga atatgttttt ataggtcaat
    29521 atccagattt ttctatgaga aaagggactc agtcaccata tgggaatgct acttatcgta
    29581 tgagaataaa aaatgaaggc aaggataagc tactaagttt agagcttcct gagatttttt
    29641 ccgcaagtga agtatggata aatggagaaa tggtttctaa attaggagat gtaggaacag
    29701 aaaaatatag acccaaaatt aaaaattcag tagtaagttt tattgcaaag aaaaatacag
    29761 aaattataat caatgtatcg aatttttcac attattatag tggtttgtat tatccgcctg
    29821 cattaggaga aacaaaggac ataagtaata tgatgtttta tcgattactt ttttatagta
    29881 taatttgctt cacaactttt gcaatagcta tattttcatt gtctgtatgg tttctttcaa
    29941 acaaaagtaa aatttactta tattttggat gtatgtgtgt tttctttgcc atccatgtat
    30001 cctatccctt tgtacatttg ttaggactgc ctttggtaag ctttacatat gcggttgaag
    30061 atttgtcata ttttatggta gttttatgta ttatttgtat aaatggaagt atatccaaaa
    30121 tagaagaaaa taaagtgtat agatttttaa ttttaccatt aggaattaca atgagtatca
    30181 tatctatagt gataccaatt attcttcttc catatgatat gtactttgtc aacatatatg
    30241 ggaagttaat agacatatat aaatatattg tatttatata tatattaatg tcttcgctgg
    30301 tttcaatata taaaaagaca tgctctgagc atataagttc ttatatttta gtttcagtaa
    30361 acactgtttt tggaattagc atattatttg atgcagttac gagtaataga tttgagccta
    30421 tatttacagg gtggcaaaca gaatattgtg ggtttgtaat tgttatttta ttttctgtta
    30481 tgatgataaa caggaataga ataataataa aagagaatga aaaacttaca aggaatcttg
    30541 aacatgaagt tgaagtgaga actaatgaac ttacaacatt gttaaatgaa cgtaaaagat
    30601 tcttggcaga tgtagcacat gatttaaagg cacctgtttc ggctatacaa gcatttatag
    30661 atttgataaa ggttggtaat attcatgtag atgaagagac aagaacctat ctttatgcta
    30721 taaatcaaaa gtcaaatgaa gtacaaaata gagtacgtag tttgcaagaa tttacatcac
    30781 aagataaaag cattggtatt agtgaaaaaa tatgtctgaa taattttatt aaagagatat
    30841 atgaaaataa tttgccagat acacaagcat gtggtgtaaa ctttgaaact tatgtattgg
    30901 agaaaaaaat atatgcaaag ataaataaag agatgcttac aagagcattt gagaatttaa
    30961 tttataatgc tttgaccttt actccatttg atggaaagat aattttatca atggataaag
    31021 aagatggatt tgcaattatt aaaatttctg ataatggaaa aggtatacct ccagaaaata
    31081 taccaaaggt atttgacaga ttctttacag aaagagacaa taatgagcca aaagggcaag
    31141 ggttagggct atatattgtc aaatccatta taagagagca tggtggagaa atatttgtag
    31201 attcagaact aggaaaagga actgttttta caataaaatt aagtctatgt tttttataat
    31261 aatagcttat ttaatataaa agaataatga tatttgggag tgattataat gcaaactaag
    31321 atattgataa tagatggaga caaggataat tgccagaagc taaaaggatt tctggaggaa
    31381 aaaggaataa gtatagattt agcatataat tgtgaagaag ctattggaaa aatatttagc
    31441 aataaatatg atttaatatt tttagaaata attctaagtg atggtgatgg atggactctt
    31501 tgtaaaaaaa ttagaaatgt aactacttgt ccaattgttt atatgactta tataaatgaa
    31561 gaccaaagca ttttaaatgc tttaaattct ggtggagacg attacttaat aaagcctcta
    31621 aatttagaaa tattatacgc aaaagtaaaa gctattttaa gaagaatgaa ctcatatgta
    31681 aataataatg aaaataatac aaaattagag gaatataata gaactagtgg agtaataaag
    31741 ttagaagata aaataataaa attgactcca acagaaaata agttgttaaa cttttttata
    31801 gagaatcctg aaaagacttt gactactaaa gagatatatg aacatgtatg gatgaatgaa
    31861 tacttagagg ataactatag tgtggtagtt gcagtgaatg gattaagaaa gaaaatagag
    31921 aaagattata aaaatcctca gaaaattata acaataagag gagcaggata ttattttaat
    31981 aaggaataat aaatatatta atatcattaa taattgttat aaatgtgaaa tactaacgat
    32041 atctaaacta aattattata aaatagctga ctgtaattta attgataaat cctattcttc
    32101 tagactttgc cagttaaatt acagtcagtt ttattatata aaaaaatgcg taatggaact
    32161 attattttat agattatatt tgaaaagatg gataaattgt atatcta
//
LOCUS       DAEPHU010000045        32186 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 01A10CD0081
            SAMN05941466-rid12468953.denovo.045, whole genome shotgun sequence.
ACCESSION   DAEPHU010000045 DAEPHU010000000
VERSION     DAEPHU010000045.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941466
            Sequence Read Archive: SRR6291087
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 32186)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 32186)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068158.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 22:43:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,892
            CDSs (total)                      :: 3,805
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 87
            rRNAs                             :: 8, 1, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 55
            CDSs (without protein)            :: 55
            Pseudo Genes (ambiguous residues) :: 0 of 55
            Pseudo Genes (frameshifted)       :: 21 of 55
            Pseudo Genes (incomplete)         :: 28 of 55
            Pseudo Genes (internal stop)      :: 16 of 55
            Pseudo Genes (multiple problems)  :: 8 of 55
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..32186
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941466-rid12468953.denovo.045"
                     /strain="01A10CD0081"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            353..1261
                     /gene="trxB"
                     /locus_tag="KR231_002229"
     CDS             353..1261
                     /gene="trxB"
                     /locus_tag="KR231_002229"
                     /EC_number="1.8.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin-disulfide reductase"
                     /protein_id="HBH0004596.1"
                     /translation="MVDIIVIGAGPAGLTSAIYAMRAGLSVTVFEKNIYGGQVASTSE
                     VENYPAVQKISGVEFSNNIYNQAVAQGVDIQFDEVEEINLEGKVKVVKTSSGEHKAKA
                     VILANGVERRKLGCAGEQEFTGRGVSYCATCDGAFFKDKEVAIVGGGNTALEDALFLA
                     NNCTKVYLIHRRDSFRGEEVLEKSVKARENIEILYSHGVEKIEGEKTVSKIEVKNLKT
                     EEKRTIDVSGIFIAIGLKPNNKMFENVLDLDEGGYIISDESCTTSVEGVYVAGDSRTK
                     FLRQIITAASDGAIAAVQAANYINVE"
     gene            complement(1351..3174)
                     /gene="typA"
                     /locus_tag="KR231_002230"
     CDS             complement(1351..3174)
                     /gene="typA"
                     /locus_tag="KR231_002230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translational GTPase TypA"
                     /protein_id="HBH0004597.1"
                     /translation="MSQKHKIINIAVIAHVDAGKSTLVDAFLSQSGVFRKNEVVKDCV
                     MDSNDLEKERGITIYSKNCAINYEDYKINIVDTPGHSDFSSEVERVMKTVDTVILLVD
                     ASEGPMPQTRFVLQKSLEFGLKPILFINKIDKKDQRAEEVVNEVFDLFVDLNATDEQC
                     EFPIIYGIAKQGIAKLEMDDDSEDLSPLFKTIVNHVEAYPNYDNEPLQFQISALAYDD
                     YVGRLGIGRIYKGTLKNNTQVAICREDSVVSKGKVSKLSVYEGLKQVEVDEATSGEIV
                     VIAGIPDISIGETICDLDSPLPMEMIKIEEPTLSMNFLVNDSPFVGKSGKFVTTRHLK
                     DRLEKELEVNVGLKVEPLDTTDGYKVSGRGELHLSILLENMRREGYEVGVSKPEVLMH
                     KEDGKLMEPIERVVVNCPEVYSGTIINELNMRKGMMESMSIEGDYVKIEFLAPTRGLL
                     GYRSEFINATRGEGTLVRSFEKFEEFKGEIPSRGNGVLIAQGPGVTMGYSLNALSDRA
                     VMFVDPGVEVYEGMIIGMNSRKDDMVVNPCKNKKMSNVRASGSDDAIKLSPPRIFTLE
                     EALEFIEDDELVEITPDSIRLRKRFLNEHDRLRYNKSRQGK"
     gene            3386..3628
                     /locus_tag="KR231_002231"
     CDS             3386..3628
                     /locus_tag="KR231_002231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0004598.1"
                     /translation="MLEVTKIIIKYFASESDTFVKEEVCNFEELLKWSHKFIEGKKIE
                     DVLYIKSKENYKVNVIKSLEIKELEIVRKQQIPPYM"
     gene            3776..3967
                     /locus_tag="KR231_002232"
     CDS             3776..3967
                     /locus_tag="KR231_002232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1450 domain-containing protein"
                     /protein_id="HBH0004599.1"
                     /translation="MIRVCPNCSNVDVNKLKTLVGEENVKTGCIGQCRAFKKEAVGII
                     DNELEIKETEAEFFEACKE"
     gene            4258..6759
                     /locus_tag="KR231_002233"
     CDS             4258..6759
                     /locus_tag="KR231_002233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper-translocating P-type ATPase"
                     /protein_id="HBH0004600.1"
                     /translation="MSSNKVVESYKITGMTCAACAKAVERVTKKMDGVYDQNVNIATE
                     KLKIEYDNSKVNFDDIKQVVEKAGYGIIKEESNKKIDMKIDGMTCAACAKAVERVVKK
                     LDGVESISVNIATDKANIDYDPSKVKLSQIKAAIEKAGYKPIEEVRNKVDVDEDKLRK
                     EREMKSLFVKFIVAIVFAVPLFYIAMGPMIIKPIGPWPLPEIINPMTNTFNYALIQLI
                     LVIPVMIAGYKFYINGFKSLFSLSPNMDSLVAIGTLAAFLYSLYTTLQIANGQIQGMH
                     HHQLYYESAGIIIALILLGKYLESKSKGKTSEAIKKLMGLQPKTAIVLVDGKEVETPI
                     EEVEIGDILLVKPGTKIPVDGVVIEGYTSVDESMLTGESIPVEKNVGSKVTGASINKN
                     GVIKFKAEKIGGDTALAQIIKLVEDAQGTKAPIAKLADTVSGYFVPIVIAIAVVASLL
                     WFLIGGKDIVFVLTIFISVLVIACPCALGLATPTAIMVGTGKGAENGILIKGGEALES
                     AHKVNTVIFDKTGTITEGKPKVTDIVLNNNVKEEYLIKIASSAEKGSEHPLGEAIVKY
                     GEEKNIKFEKVDNFKAIPGAGIQVTINDESILLGNRKLMNDNNIKLGDLEEKSNILAS
                     QGKTPMYIAVDGNLSGIIAVADVVKESSKKAIEILHDMGIKVAMVTGDNAKTANAIAN
                     QVGIDMVLAEVLPEDKSKEVEKLQNQGKFVAMVGDGINDAPALAKADIGIAIGSGTDV
                     AIESADIVLMKSDLIDVPTAIKLSHETIKNIKQNLFWAFGYNTIGIPVAAGILYVFGG
                     PLLNPMIAAAAMSLSSVSVVSNALRLKNFKAYKRD"
     gene            6919..7587
                     /locus_tag="KR231_002234"
     CDS             6919..7587
                     /locus_tag="KR231_002234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBH0004601.1"
                     /translation="MNSSILVIEDDSNIQELISEFLSAEGYQVDTANDGLEGIQKFKQ
                     GSYDLVILDIMMPNLDGYGVCKMIRKSSSVPIIFLTALNDEGDQLKGFDLECDDYITK
                     PFSFNLLIKRVEAILRRSNKTINDKFIVFEKLKLDLNTYIAEIDGEPIELTLKEFNIL
                     KALIEKYPQVITREGLLDSIWGYDYYGDTRIVDAHIKNIRKKISLPYIKTVKGIGYTL
                     EKDI"
     gene            7571..8848
                     /locus_tag="KR231_002235"
     CDS             7571..8848
                     /locus_tag="KR231_002235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component sensor histidine kinase"
                     /protein_id="HBH0004602.1"
                     /translation="MRRIFDKWEKLSIKYKLFSITTSLLIALALIIYLILYFLLPSYY
                     HEYKIESLQESLKSLVDSSIHFDTYTLEERLYYMAKDQNLAILLKDNQGKIVYGKNEV
                     VILRYSKYMINSLEDEYRTSIPIYTKDAKDGPYTLELVMPLQPIDEANEVIRKLMPYI
                     ISIAILIAIIGAYIYSIVITKPLINIIESEREQEYRRKDFVATISHELKTPITIISGQ
                     IEGMIYSVGKYKDRDTYLKKSYECTQELKDLVNEMIEVSKSEILEKDLKLVSINISEL
                     LNRLVKRQVFLIEEKHMKTILKIEENLEIKADQERITKAINNIINNAIKYSPEESELI
                     IRLYDKNKRISKKTSNQRVVLEIENTGVTIEKRYLEEIFNPFYRIEKSRSRKTGGSGL
                     GLYIVSQIFKSHGFDYSIKNKENSVVFTVEFKN"
     gene            9249..9470
                     /locus_tag="KR231_002236"
     CDS             9249..9470
                     /locus_tag="KR231_002236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0004603.1"
                     /translation="MDRLKRDMKNMKEDLKEGVKKTAYVMKNTAEDLKDDAQGAMVNL
                     EMKKDEMMERYEQKKFSKELEKQMKNEMK"
     gene            complement(9759..10523)
                     /locus_tag="KR231_002237"
     CDS             complement(9759..10523)
                     /locus_tag="KR231_002237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HBH0004604.1"
                     /translation="MFAEERIQAILNILKKEGRVTVKELSSKFNVTEDCIRKDLKNIE
                     KISSIRRIYGGAVLARETLENQDTKDRKEINIPTKKIIAEKAFNLIEDRETIFLDIST
                     INILLAKLLAESNKKVTLVTNMLDILNVVTSKPNNLNIISTGGLLNLSLDGFVGTPTI
                     EFISKYKFDKTFMGSCGVDVFNSSLTTFEIEDGLTKKAIINSSKKVFIVMEDKKFKFD
                     GNFKFAHLEDISSIITEKTPTPDIVDILSEFNVNVL"
     gene            10797..11471
                     /gene="fsa"
                     /locus_tag="KR231_002238"
     CDS             10797..11471
                     /gene="fsa"
                     /locus_tag="KR231_002238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-6-phosphate aldolase"
                     /protein_id="HBH0004605.1"
                     /translation="MQLILDTGNVEEIKELCTCLPIDGVTTNPSIVSKEKKNFKQLIN
                     EIGEIIGEDMPIHAQVLSTKYEEILEEALYISSLRKNIYVKIPVTQDGLRAIKDLHRK
                     GVKITATAIFTAHQGFLAAKAGANYIAPYVNRLDNISGDGVAMVSELIKIIDTYKMDT
                     KVLAASFKNAQQVIELMQHGVHSVTVPYDICKSMMNHPLTDWSVDKFIEDWENTFGKG
                     SKTNNI"
     gene            complement(11593..12987)
                     /locus_tag="KR231_002239"
     CDS             complement(11593..12987)
                     /locus_tag="KR231_002239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SLC13 family permease"
                     /protein_id="HBH0004606.1"
                     /translation="MGIILKPKQFYMTVIATIILYFSLNYSFNIKFSICLSFLTILIW
                     AVDSVEKTFVALFFVILAFIFNIAPIKVILQFLFTENFYIIILAYIITNAVTKTGVAK
                     IISEKLILNTVNTPKKMILLSYILGILLIFFIPQPFPRVILVSAFYKEFLKEQQITED
                     SKSILLFSIFTASTFTSMFFVNGDTLLNYVVLELGNCNINWGQWAFYMSVPTIITCFI
                     TYFLFTFVFKKELHSIKFISNENLEGNKLHFSYSNLKKEFNLLNKEQKHVFLCLGIMF
                     FMFLTQFIHNINTLIIMSICVLLLLLRKIVGFSTLKEINWKVLIFFIAAFSIGGVLKY
                     SGVVDIMGNYLIKFIPNSSEIISILFLITLTIILNICLGSAVTTSSVVIPLLGSLHIL
                     KENSVTLCLFVYIIVSIQYILPFHHATIMVGHGENLYNSKVIFKYGLTLIPLTYFIII
                     CITFPWWKFIGLEI"
     gene            complement(13065..14411)
                     /locus_tag="KR231_002240"
     CDS             complement(13065..14411)
                     /locus_tag="KR231_002240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HBH0004607.1"
                     /translation="MKDLTTGHEGKSIFFFAMPMLIGSLFQQLYNTADSIIVGRFIGK
                     EAMAAVSGANPIMFLLVAALMGVSLGFSILVSQFYGSGDLKKVKATIDTTYILLFIGS
                     ILISILGIVFGGPMLKLMNTPESVFAQSKLYLTIIFSGILFSAGYNSVSAILRGLGDS
                     VTPLYFLIIATILNIVLDLTFIVVLRMGVEGVALATIMAQAVSFIISIIYLNKKHEVL
                     KFKIKGIVYDNKIFKDGLRLGLPSGVQQMLFSIGNMALQFLVNSYGTSAMAAFGAGLR
                     IENFISLPIMNLGSAVSTFVAQNIGAGENERVKKGIRESIKMTLVLAVTVIALILLFR
                     ENLIALFNTDKDVIKIGSSYLFIIGPFFLFIGTSFVLSSAMKGAGDSMFALISSIVSL
                     WLGRLPASYMLSKFFGTDGIWMGIPFGWTLGLIVTVIYYKKGHWKTKAIVNHRINE"
     regulatory      14661..14763
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00167"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="purine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="guanine and/or adenine"
                     /db_xref="RFAM:RF00167"
     gene            14857..16233
                     /locus_tag="KR231_002241"
     CDS             14857..16233
                     /locus_tag="KR231_002241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NCS2 family permease"
                     /protein_id="HBH0004608.1"
                     /translation="MQTTNSSTMQKLFPILTNKNVDMKKEIIAGVTTFLTMAYIIAVN
                     PNILSETGMPAGALVTGTCLAAAFGCILMGVVANLPFALASGMGLNAFFAYTVVLQMG
                     VPWEVALTAVFVEGIIFIVLSVSGVREAVVNAIPKNMKLAVTGGIGIFIALIGLVNSG
                     IVIGDQATLIKMGRFTPAVIITCVGLIIIAVLDKKRVKGSILFGIVVSSLLAWAFAFI
                     NPEYAQKLGIYLPGGLFKFESLAPIAGKIDLGYVLHPTNIGGFLVVVCTFLFVDFFDT
                     VGTLVGVCSKANMLDEKGNVPNVGRALLTDAVATTVGAGLGVSTVTTYVESSTGVIAG
                     GRTGWTAITVGILFLAAMFFSPVFIAIPSCATAPALIYVGYLMLGTVKDIEFDNITEG
                     VPAFVTIACMALTYSIGDGLTLGILTYVFVNIFYNIFGAKKAEDKKHVSVVMIVLAIL
                     FIIKLWLL"
     gene            complement(16347..17492)
                     /locus_tag="KR231_002242"
     CDS             complement(16347..17492)
                     /locus_tag="KR231_002242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HBH0004609.1"
                     /translation="MNTFEQLKISSTLIDGLKKQDITSPTEVQSLVIGNIIQNKDLLI
                     NSQTGTGKTLAYLLPIFEKIDTSKRETQALILAPTHELVMQITNQVELLAKNAELSVT
                     SLALIGEVNIQKQIKNIKAVKPHIVIGSCGRVLDLIKQKKLKSHNIKTIVLDEVDNLL
                     NGKNITCIEDIIRTTLRDRQIIGCSASLTDSTIKICDKLMKEFEIIKTKEKSQINPNI
                     NHSYLLGEIRDKFTFLRKALAATNPKKAIVFVNNEKNIEVLVSKLNYHNYKAIGIFGN
                     MEKEDRKNAINKFKLGKAKILITTDLSARGLDIVDVSHVFNLDFPKSKNEYLHRCGRT
                     ARGNRSGNTISIITKKELDIIKDLQKEFNIVITPKTLQNGELIDIIK"
     gene            17745..18452
                     /locus_tag="KR231_002243"
     CDS             17745..18452
                     /locus_tag="KR231_002243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH0004610.1"
                     /translation="MLKVINVSKSYKNKKVVSSVSFDVNDGELFGFIGHNGAGKTTTI
                     KAIVGIHDFEEGEVLINSKSIKKQPVECKKEMAYIPDNPDLYESLTGIQYLNFIADIF
                     EVAKDKREELIKYYSNKFELNKALGDLISSYSHGMKQKLAIISALIHSPKILILDEPF
                     VGLDPKASFILKEIMREFCDKGGCIFFSTHVLEVAEKICDKIAIIKDGNIIAYGTTEE
                     VKGSNSLESIFMELIEK"
     gene            18499..20094
                     /locus_tag="KR231_002244"
     CDS             18499..20094
                     /locus_tag="KR231_002244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBH0004611.1"
                     /translation="MSNLSILIKTNIINEFKLNALKKADGREKQKIMGMMLSVVIIAG
                     LLIFYVTSLSLSLVDILKQINQLEMLLIFGFGLSTLTTIVTSLYKTSSYLFQAKDLDL
                     LTSLPIKESTVLASKILMLVGANYLFSSICMLIPAVVYFLNSDVSITYFPYLILLFLA
                     LPLLPIVASSIIFLFIGQISSRIKYKNLVLIIGSIILMLLYTLLMSRLNSMSVEMLKN
                     SVSISETIRKVYPPIYYFVDALKTGSIVSFLAFIAISIIPFFMFVTLFAKKFKDINAK
                     MSEGYKSKNYEFKGQKTSRPSKALLKKEFKRYTSSFIYFLNSSAGLLFLIVGTILILL
                     FGADKVGELLKLNIDFNLIKIQLLGVFFFIIVMNCTTYCSISLEGKNLWILKSSPIDE
                     REIFWSKILMNFLLNAPLSILCLILVSIRLDFEIQFIIVSICLIVSFSMFVALMGLLS
                     NLLYPNLDWKNEVAVVKRSASMIVTMLVSLAYVIILGGIYVLLGISFLNIYIILASIL
                     TLILDFMIWRIISTKGVRIFKNL"
     gene            20197..21279
                     /locus_tag="KR231_002245"
     CDS             20197..21279
                     /locus_tag="KR231_002245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flippase-like domain-containing protein"
                     /protein_id="HBH0004612.1"
                     /translation="MRKLSKREKDFIQYGFLLFLICITTYLVLTTLDIKLIPKIIRLV
                     NKTYIFLGILTIIVYMIIESIVTHLIINAVQKTKVKFIGIKMATMGFYYNLVTPFASG
                     SQPMQIYALTKYDVSLSKSVAIVTNKTVVFQSTVTVFCGILILLNKSLLMEQVHSVKV
                     LITFGMIMNVSMLLGGLLIVFSPKQVKMIAEVLINFLSKFKTFKFLDSKRDRINHYID
                     DYNYSIKIFIKNVRILVLSILLTVLQLIAYFSIVYCVYKASNLRGVSYVHIMTLQVFL
                     YMAISPIPTPGNVGANEVTFFTMFSNIIPKELLGYSVLLYSGFVYYFILIVSGLFTFG
                     THYTLNSWKKENKVNSNLDKVIEKLN"
     gene            21428..21589
                     /locus_tag="KR231_002246"
     CDS             21428..21589
                     /locus_tag="KR231_002246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III"
                     /protein_id="HBH0004613.1"
                     /translation="MKQDKQNEKQSEISKIKQSNDNKLEIAQELHVSKNIGNMLGYRI
                     DKKKMNRPS"
     gene            21930..23198
                     /locus_tag="KR231_002247"
     CDS             21930..23198
                     /locus_tag="KR231_002247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation:proton antiporter"
                     /protein_id="HBH0004614.1"
                     /translation="MEASIHTIASNNLLIIFAIVSITGIICSKLSEIIKVPDVVLYLL
                     VGILIGPSFLKFIDIRGFQIENQLILTFGSAFILYLGGKEISLKVLRNVKISVFLLAT
                     LGVVISAFIMQQVIGFTFGISAMTALLAGTIIASTDPATLVPIFNQVKIKDRVKQTVI
                     SESAFNDATGAILTSAVLAVILSNKFSLGENIYELGTMVIVGVLVGLITGILLLKLVN
                     DKPYGIFKDFAPIISVISVVVAYELSTKLGGSGYMSCFIVGIITGNKKNFKIWLSQKS
                     YDADFYVAETLGTICRMAIFIILGSQVNLAQLSKYFMPSVITVLVLMFIARPLCVLVC
                     TLVDREAKWSKSEILFMMWVRETGVIPAALCGIISAMKVPGYEVISSVVFMTILITLV
                     IQGSTTKLVAKKLGLLEEEVINISEKVSTF"
     gene            23393..24181
                     /locus_tag="KR231_002248"
     CDS             23393..24181
                     /locus_tag="KR231_002248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD binding domain-containing protein"
                     /protein_id="HBH0004615.1"
                     /translation="MFTVMDIVQPDTVEEAYSILNKRKTNQVIGGSAFLRMGKKRIGT
                     GIELSKLNLDYIKEYEDYVEIGSMTTFRTLETSSIIKNNFGRIIEDSVKNIIGVQFRN
                     VVTVGATVFSKYGFSDLIVALLSLDTEVELYNIGRISLEEFLNRDYEKDLLIKIYIKK
                     TNKNASYKSLRNAKSDYPILNVSVSKHMEQFKLCVGARPQKATIAKQASEFLSNNEIN
                     EINIDKAVEIASEELTFGSNMRASREYRKAMSKVLLKRAIMEVI"
     gene            24181..24630
                     /locus_tag="KR231_002249"
     CDS             24181..24630
                     /locus_tag="KR231_002249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2Fe-2S iron-sulfur cluster binding
                     domain-containing protein"
                     /protein_id="HBH0004616.1"
                     /translation="MLVKININGKKKSVDIEPEEYLVDTLRKVGNLSVKRGCDTGCCG
                     LCTVLIDKKPTLSCATLTLRALDKEITTIEGLENEVKEFSEVLVKEGAEQCGFCSPGF
                     ILTVLAMKDELENPTDDEIKHYLTGNLCRCTGYMGQLRAIKTYLEVK"
     gene            24634..26898
                     /locus_tag="KR231_002250"
     CDS             24634..26898
                     /locus_tag="KR231_002250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdopterin-dependent oxidoreductase"
                     /protein_id="HBH0004617.1"
                     /translation="MNIVGKGIKKIDGMSITTGKPVYTDDLSAKDALVVKILRSPHAY
                     AKIKDIDTSKAEMVDGVECVLTYKDVPKSRFTLAGQTYPEPSPYDRLILEDVVRYVGD
                     EVAIVAAIDEKTAIKAMNLIKVKYEVLTPVLDFEEAIGNKTMVHDEDRHCNFDIGMQR
                     EKNIVSHHDYTKGDVEKVLSNCDVVIEETYYTQAQAHAMMETYRAYNYLDHMGRLVVV
                     SSTQIPFHVKRHLSRALEIPASKIRVIKPRIGGGFGGKQTACVEIFSAIVTLKTGKPA
                     KIIYDRKETFNCSTSRHAMRLKVRLGATNDGIIKAIDIKALSDTGAYGEHASTTIGLV
                     GEKTLPMYNKVEATRFIADVVYTNKMPAGALRGYGASQGCFAVESTINMLANKLKMDP
                     TDLRLKNVVTEGETTFAYGKTLNSVDLIKCINKGKELIGWNEKYPCKHLDNGKIRSVG
                     MAITMQGSGIQGLDKSSAEIKLNDCGDYTLMIGSTDMGTGSDTILAQMAAEVLDTSIE
                     NITVISADTDLVPYDPGSYASSTTYVTGMAVVKAAQDLREKIISAGATKLGVEKDEVK
                     FDGIKLTSKKGSTLLFDIAVDSTIGPDTNQLIGLASHGSPVSPPPFIAGFAETEIDTE
                     TGKVDLVNYVAVVDCGTVINKNLAKIQVEGGIVQGIGMALFEEVRYTEKGRMDTNTFM
                     QYKIPARCDIGNVKVDFVETYEPTGPFGAKSVGEVVINTPLPAIQEAVFNGIGVRINT
                     LPITPEKVFMEMNK"
     gene            27038..27349
                     /locus_tag="KR231_002251"
     CDS             27038..27349
                     /locus_tag="KR231_002251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433131.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0004618.1"
                     /translation="MAGNLNNMRAVNNFRGDKNILECLVSFEGRSISQRKVRVFFKEK
                     QNQIEIDFAEEEISKLVENVVLNTSYQEMLYDEIEKQLEIDCIGTWMILSKLKDGSRV
                     H"
     gene            27635..28135
                     /locus_tag="KR231_002252"
     CDS             27635..28135
                     /locus_tag="KR231_002252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="QueT transporter family protein"
                     /protein_id="HBH0004619.1"
                     /translation="MRKNSINIALTAAITAIYAVLTLSLGFISYGPIQFRVAEIMMLL
                     AFLDKGYIVGLTLGCFLANVIGPYGVPDIIFGTLATFISASMIYITRKLGKQNKSTLV
                     IASLWPTVINSIVVGLMLNVFFGLPLILSMIQVGFGEFVVVTIVGVPFFCFLMKKYKN
                     VINIKF"
     gene            28192..29178
                     /locus_tag="KR231_002253"
     CDS             28192..29178
                     /locus_tag="KR231_002253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WYL domain-containing protein"
                     /protein_id="HBH0004620.1"
                     /translation="MSKVKRLTDVWIYINDKQKFTIKELSEEFNLSAKTIQRYLKELN
                     KMGLPIQAEQGRNGGYRVLNNSYIPPVIFTEKEVMIILFALKSLQIYNYKLMEIEINS
                     IMRKVSYERKSSIKVGIENIKRYIGFVANDTNDGDFKSSNVTEFFRASSESLILNIKY
                     KCGNQILEKNVCPIGIYLNKGAWFSPAYDCKSDKIILVHIDNIIDIKRTGESKKIHIN
                     LEEWLHEVYNNLYGNSSTTKKFGEIIYLNVLLTKEGVSKIKDSSWNLDMELNEDGSGI
                     ISTFIKVEDIDCYASILFFIGNNAKVIEPKFLNKLLYDKANELRYFYEENMV"
     gene            29228..29950
                     /locus_tag="KR231_002254"
     CDS             29228..29950
                     /locus_tag="KR231_002254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein"
                     /protein_id="HBH0004621.1"
                     /translation="MENFNKNAKIIGIGAEGINIINEVEEKIKANMDIEKININQEIE
                     KEYVRSLLDGVDILFLIYSSEDKHIRDIIKAVSYMSNERRVLSIGMDCSEKENKEDLE
                     LGREFKINNDSIFKFVDLMNIMVESISDSCMINIDITDLKEAIVGDKGIKYSFEEFED
                     TKSYSEIADILFDRMEYIGEEFISKKGIVFVEGSPEFSIMELNDLISNIQSKVEESYE
                     VIFSLYIKENLNGNIRVGLLYN"
     gene            29979..31913
                     /locus_tag="KR231_002255"
     CDS             29979..31913
                     /locus_tag="KR231_002255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HBH0004622.1"
                     /translation="MSENIRGTEYWLMEEFFYQETDTPQIFREESIIALGFDIKINLK
                     KVFSMGKKSEKYINENCNDKDFIKKFMSIKKGDYFLYKAYQNIEEKVKCNVSIGIVEE
                     DFENGYELSHILGHTLPVKWMHNFDTVSNCKVYTSEFYKLNNNDISSYLEIIKSQDKK
                     LLRKRIEESENNKWYLKNYYYKNVDKCVDDEELFIQPINLEQLESLKNIKTDDYILLY
                     NSEKVICENDHTMKSLFGVCQVMEGFDKEKVSALEGGYFFPVRWIEYEKENIDGNAWV
                     IFENNSIVEKYVKRFTNKMPLNTILYGPPGTGKTYNTKQMVYNLVSETSLRNKYYTGY
                     LDYKNNVEFCTFHQSYGYEEFIEGLKSDGEGNFKQEDGILKDISIEACYNALKFEKKM
                     SFELEKDSLTLETIKDRKKKLVLENIEYSESFNFEESENYVLIIDEINRGNVSKIFGE
                     LITLLEDDKRLTKSNQTIVKLPYSKEKFSLPPNLYIVGTMNTSDKSIALLDIALRRRF
                     NFEEIMPDYDLLSIVDGIDIRKMLYTINKRIEFLYDRDHVIGQAYLLAVENINDIVVV
                     FRSKIIPLLQEYFYYDSEKVGLILGGIGRNEKDKYIVYKEKLIASELFKNNNASIMES
                     KVNYCIKQNISSEELKNIYE"
     gene            31906..>32186
                     /locus_tag="KR231_002256"
     CDS             31906..>32186
                     /locus_tag="KR231_002256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0004623.1"
                     /translation="MSKNIYVKETYEWIRVGNGENELTEIEYEKLLKYLENNNDVLKS
                     NIIDIKYKKLRFINYVGIICFENVILEILPKLSLSDNLVKDREILLQMLS"
BASE COUNT        12446 a         3537 c         5300 g        10903 t
ORIGIN      
        1 acataataat agtatactgt aaacaaaagg aggtattaaa tatgggaata gtacttataa
       61 cagcagcatt agttttggtt atgtatggac tttcaattct atcatatata tcagaaagca
      121 atatattaga agacactgta aatgataacc aataaggttt tgaattatat aaataagtga
      181 gaactgtaaa taaaagttaa tttttatttg cagttttttt atatatatgt aaaataaagt
      241 taattaataa aaaataatgt tttgtttata gtatatatgg ataataatag taaagtataa
      301 gaatgatgag aataatatat aagaaataat aatataaaga gaggtaaacg ttatggtaga
      361 tatcattgta attggtgctg gaccagcagg tttaacttca gcaatttatg ctatgagagc
      421 agggttaagc gttacagtat ttgaaaaaaa tatttatgga ggtcaagttg caagtacctc
      481 tgaggtagaa aattatccag cagttcaaaa gatttctggg gtagaatttt ctaataatat
      541 atacaatcaa gcagttgctc aaggtgttga tattcagttt gatgaggttg aagagataaa
      601 tttagaggga aaagtaaagg ttgtaaaaac ttcttcaggt gaacataaag caaaggctgt
      661 tattcttgca aatggagttg aaagacgtaa attaggttgt gcaggggaac aagaatttac
      721 aggtagagga gtatcttact gtgcaacatg tgatggagcc ttttttaaag ataaagaagt
      781 tgctatagta ggtggaggaa atactgcact agaagatgct ttatttttag ctaataattg
      841 tacaaaagtg tatttaattc acagaagaga tagttttaga ggtgaagaag tgttggagaa
      901 atctgtgaaa gcaagagaga atattgagat actttacagt catggtgtag aaaaaataga
      961 aggagaaaag actgtatcga aaatagaagt aaaaaactta aagactgaag aaaaaagaac
     1021 tatagatgtt agtggtattt ttattgctat aggtcttaaa cctaataata aaatgtttga
     1081 aaatgttctt gatttggatg aaggtggata tataatttca gatgagtctt gtacaacatc
     1141 agtagaaggt gtatatgtag caggagatag tagaactaag tttttacgtc aaataataac
     1201 agcagcatca gatggagcta ttgcagccgt tcaagcagct aattatataa atgttgaata
     1261 atataaattt caaataaaaa tagccatata aactgaaata atttttcagt actatatggc
     1321 tattttgtta attagaggta aatgtacgtt ttatttacct tgtctagatt tgttatatct
     1381 taatctatca tgttcattta agaatctttt tctaagtctt atagaatcag gtgtaatttc
     1441 aactaattca tcatcttcta taaactctag agcttcttca agagtaaata ttctaggagg
     1501 agataatttt atagcatcat ctgaaccaga agcacgtacg ttactcattt tcttgttttt
     1561 acaaggattg actaccatat catcttttct ggaattcata ccaattatca taccttcgta
     1621 aacttctaca ccagggtcta caaacattac agctctatca cttaaggcat taagagaata
     1681 ccccatagta acaccaggtc cttgtgctat taaaacacca tttcctcttg aaggtatttc
     1741 tcctttaaat tcttcaaatt tttcaaatga acgaactaaa gtaccttctc cacgagtagc
     1801 gtttataaat tcacttcgat atcctaaaag accacgagta ggtgctaaga actctatttt
     1861 tacatagtct ccttctattg acatagactc catcatacct tttctcatgt ttaattcatt
     1921 tataatagta ccagagtaaa cttcaggaca gtttacaaca actctttcta ttggttccat
     1981 tagttttcca tcttctttat gcattaaaac ttcaggttta gaaacaccaa cttcataacc
     2041 ttcacgtctc atattttcaa gtagtataga taagtgaagc tctccacgtc cagaaacttt
     2101 gtatccatca gtagtatcaa gaggttcaac tttaagacca acatttactt caagttcttt
     2161 ttcaagtcta tctttcaaat gtctagttgt aacgaatttt ccactttttc caacgaatgg
     2221 agagtcgttt actaagaagt tcatagaaag agtaggctct tctattttta tcatttccat
     2281 aggtagtgga ctatctaaat cgcatatagt ttcacctata gatatatcag gaataccagc
     2341 tataacaact atttctccac tagtagcttc atcaacttca acttgtttta aaccttcata
     2401 cacagaaagt tttgatactt ttcctttaga tacaacagaa tcttctctac atatagcaac
     2461 ttgtgtattg tttttaagag tacctttgta aattctacct ataccaagtc tacctacata
     2521 atcatcatat gcaagagctg atatttggaa ctgtagaggt tcattatcgt aattaggata
     2581 agcttcaacg tgatttacaa tagttttaaa tagaggagaa aggtcttcac tatcatcatc
     2641 catttcaagt ttagcaatac cttgtttagc aataccatat attataggaa attcgcattg
     2701 ctcatctgtt gcatttaagt ctacaaataa atcgaaaact tcattaacta cttcttccgc
     2761 tctctggtct tttttatcaa tcttgtttat aaataatatt ggttttaaac cgaactctaa
     2821 agatttttgt aaaacgaatc tagtttgagg cattgggcct tcactagcat caactaatag
     2881 aataactgtg tcaacagttt tcataacacg ttcaacttca gaagaaaagt cactgtgtcc
     2941 tggagtatca actatgttta ttttgtaatc ttcatagttt attgcacagt tttttgaata
     3001 tatagttatg cctctttctt tttcaaggtc gttactgtcc ataacgcagt ctttaactac
     3061 ttcgttcttt ctaaaaacac cgctttgaga aaggaaagca tcaaccaatg ttgattttcc
     3121 agcgtcaacg tgggctataa ctgcgatatt tataatttta tgtttttgtg acatttttgt
     3181 tgctcccttc gattaaaata acttattaat tatagcacaa tatattatta ggtacaagga
     3241 ggaatatatt aaattgtatt aatatagttt aaattggata aaactgttag ttttgcatct
     3301 gaaaattatt ctgtttaaaa aaatttttta gacaaataat aaccttaata gataaaaaga
     3361 ttaataaaag agtaaaggat gatatatgtt ggaagtaacc aaaataataa ttaaatattt
     3421 tgcaagtgaa agtgatactt ttgtaaaaga agaagtttgt aattttgaag aacttcttaa
     3481 gtggtctcat aaatttattg aaggtaaaaa gatagaagat gttttgtata taaagtctaa
     3541 agaaaactat aaagtaaatg tgattaagtc tttagaaatt aaggaattgg aaatagtgag
     3601 aaaacaacag ataccaccgt acatgtagta ttaataatat ataaaattaa tatgtaatac
     3661 tcgcaatagg atataaatgg tatatatggt aataatttat attaaaaaaa cttttataaa
     3721 gtttatattt gggtataaaa gtattaatta gacattaatt aggaggaact taaatatgat
     3781 aagagtatgt ccaaactgtt caaatgtgga tgtaaataag ctaaaaactt tggttggaga
     3841 agaaaatgta aagactggtt gtataggtca gtgtagagca tttaaaaaag aagctgttgg
     3901 aataatagac aatgagcttg aaataaagga aacagaagca gagttttttg aagcatgtaa
     3961 agaataaatt ttaaataaaa tataaattat aataaataga gcatctaaat tgtataagca
     4021 ttaaacaatt tagatgctct atttttatat atacatttaa ttatgagtat acttttctat
     4081 taaatacaaa taaatataac taatacattt atttattaaa aaaatattga tttaatatac
     4141 ctataggggg tataatgaaa atatagattt ctaaataagt aatttatcaa tattacatat
     4201 caaaataaaa cgttacaaat tagctgaaaa tatattgaaa gaaaggaaga ttttattatg
     4261 agttcaaata aagtggtaga aagttataaa attacaggta tgacatgtgc agcttgtgca
     4321 aaggcagtag agagagtaac taagaagatg gatggagtat atgaccaaaa tgtaaatata
     4381 gctactgaaa aacttaaaat agaatatgat aattctaagg ttaattttga tgatataaag
     4441 caggttgtag aaaaagcagg atatggaatt ataaaggaag aaagtaataa aaaaattgat
     4501 atgaaaattg atggaatgac atgtgcagct tgtgcaaaag ctgtagagag agtggtaaaa
     4561 aaattggatg gagtagaaag tattagtgtg aatattgcaa cagataaagc taatatagac
     4621 tatgacccat caaaagtaaa attatctcaa ataaaagcag ctattgaaaa agctggatat
     4681 aaaccaatag aagaggtaag aaataaggtt gatgtggatg aagataaatt gagaaaagaa
     4741 agagaaatga agtctttatt tgttaaattt atagttgcaa tagtatttgc agtacctctg
     4801 ttttatatag caatgggacc tatgataata aagcctatag ggccatggcc tttgccagaa
     4861 attataaatc ctatgacaaa tacttttaat tatgcattaa ttcagttaat tttagtaata
     4921 ccagtaatga tagctggtta taaattttat ataaatgggt ttaaatcact tttttcttta
     4981 agccctaata tggattcttt agttgcaata ggaacattag ccgcattttt atatagtcta
     5041 tatacgacac tacaaatagc caatggacaa attcaaggta tgcaccatca tcagttgtat
     5101 tatgaaagtg caggaataat aatagcactt atcttacttg gtaaatattt agaatcaaaa
     5161 tcaaaaggaa aaacatcaga agcaattaaa aagcttatgg ggctacaacc taaaactgca
     5221 atagtgttag ttgatggtaa agaagttgaa actcctatag aagaagtaga gataggagat
     5281 atactattag taaaaccagg aactaaaata cccgtggatg gagttgtaat agaaggatat
     5341 acatcagttg atgaatcaat gcttacaggt gaaagtatac cagtagaaaa gaatgttgga
     5401 agtaaggtga caggagctag tattaataaa aatggtgtta ttaagtttaa ggctgaaaaa
     5461 attggtggag atactgctct tgcccaaata ataaagttag ttgaagatgc acaaggtaca
     5521 aaagcaccta ttgctaaact tgccgatact gtatctggat attttgtacc aatagtaatt
     5581 gcaatagctg tagttgcatc attattgtgg tttttaatag gaggaaaaga tatagtattt
     5641 gtacttacta tatttatatc agtacttgta attgcttgtc cttgtgcatt aggattagca
     5701 acaccaactg ctataatggt tgggactgga aagggcgcag aaaatggaat cttgataaaa
     5761 ggtggagagg cactagaatc tgcacataaa gtaaatacag tgatatttga taagacaggt
     5821 actataacag aaggaaagcc aaaagtaaca gatatagtat taaataataa tgtaaaagaa
     5881 gaatatctta tcaagattgc ttcaagtgca gaaaaaggtt cagaacatcc tcttggagaa
     5941 gcaatagtta agtatggaga agagaagaat ataaaatttg aaaaagttga taattttaaa
     6001 gctataccag gtgctggtat acaagttact attaatgatg aaagtatatt acttggaaat
     6061 agaaagctta tgaatgacaa taatataaag cttggagatt tagaagaaaa atcaaatata
     6121 ttggcaagcc aaggtaaaac acctatgtat atagctgtag atggaaattt atcaggtata
     6181 atagcagttg cagatgtagt caaagaaagt agtaaaaaag caatagaaat acttcatgat
     6241 atgggaataa aagttgcaat ggtaactgga gataatgcga aaactgcaaa tgctatagca
     6301 aatcaagtcg gtatagatat ggttttggca gaggttttac cagaagataa gtcaaaagaa
     6361 gttgaaaaac tacaaaatca aggaaagttt gttgcaatgg taggggatgg aataaatgat
     6421 gccccagctc ttgcaaaagc agatataggg atagcaatag gaagtggaac ggatgtagcc
     6481 attgaatctg cggatatagt acttatgaag agtgatttaa ttgatgttcc aacagcaatt
     6541 aaacttagtc atgaaactat aaaaaatata aaacaaaacc tattttgggc atttggatat
     6601 aatacaattg gtatacctgt agcagcagga atattatatg tatttggagg acctttatta
     6661 aacccaatga ttgcagcagc agcaatgagc ttaagttcag tttcagtcgt atcaaatgca
     6721 cttagactta aaaacttcaa ggcatataag agagattaga ttaataaatt aaataaaatg
     6781 tatccaaaag agctatcttt aaattaaaag gattaattta caaattaaga tagctctttt
     6841 ttcatgtaaa attcacaaca ataagataaa atataagtaa tatacgaaat tttaaataaa
     6901 atagaaagga ttgatagaat gaattcgtca atacttgtaa ttgaagatga ttcaaatata
     6961 caagagttaa tatcagaatt tttaagtgca gaaggttatc aagttgatac agcaaatgat
     7021 gggttggaag gtatacaaaa gtttaagcaa ggaagttatg atttagtaat attagatata
     7081 atgatgccaa acttagatgg ttatggagtt tgtaaaatga taagaaagtc atcaagcgtt
     7141 ccaattatat ttttaactgc tttaaatgat gaaggagacc aacttaaagg gtttgactta
     7201 gaatgtgatg attatataac aaaaccattt tcatttaatc ttcttataaa aagagtagaa
     7261 gcaattttaa ggcgaagtaa caagactata aatgacaaat ttatagtttt tgaaaaatta
     7321 aaattagatt taaacacata tattgcagag atagatggag aacctataga acttacacta
     7381 aaagagttta atatattaaa agctttgata gaaaagtatc cacaagttat aactagggaa
     7441 ggtcttttgg atagtatatg gggttatgac tattatggag atactaggat tgttgatgca
     7501 catataaaaa atataagaaa aaaaatatca ttaccatata ttaaaactgt aaaaggaata
     7561 ggatatacac ttgagaagga tatttgataa gtgggaaaag ttaagtataa agtataagtt
     7621 attttcaata acgacatcat tattaatagc attagcttta ataatatatc taattttata
     7681 ttttttattg ccatcatatt atcatgagta taaaattgag tctcttcaag aaagtttgaa
     7741 atctttagta gatagttcaa ttcatttcga tacatatact ttagaagaaa gactttatta
     7801 tatggctaaa gaccaaaatt tggctatttt attaaaagat aaccaaggta aaattgtata
     7861 tggtaagaat gaagtagtta ttttaagata tagtaagtac atgattaata gtcttgagga
     7921 tgagtataga acttctatac ctatatatac taaagatgca aaagatggtc catatacttt
     7981 agaactcgtt atgccattac aaccaattga cgaagcaaac gaagttataa gaaaactaat
     8041 gccatacatc atatcaatag caatattgat agcgattatt ggagcatata tatattcaat
     8101 tgtaataaca aagcctctta taaacataat agagagtgag agagaacagg aatatagaag
     8161 gaaggatttt gttgctacaa tatcacatga actaaaaact ccaataacca taataagtgg
     8221 tcaaattgaa ggtatgattt atagtgtagg taagtataag gatagggata cttatctgaa
     8281 aaaatcgtat gagtgtacac aagaattaaa agatttagta aatgaaatga tagaggtttc
     8341 aaaatcagaa atacttgaaa aagatttgaa attggtatca ataaatataa gtgaattatt
     8401 aaatagactt gtaaagagac aagtattttt aatagaagaa aaacatatga aaactatttt
     8461 aaaaatagaa gaaaatttgg aaattaaagc agaccaagag agaataacta aggcaatcaa
     8521 taatataata aataatgcca taaaatattc tcctgaagaa tcagagctta taattagact
     8581 ctatgataaa aataaacgaa taagtaaaaa gacttctaat caaagagtgg ttttagaaat
     8641 tgaaaatact ggtgtaacta tcgagaaacg ttatttagaa gaaatattta atccatttta
     8701 tagaatagaa aaatctcgtt caagaaaaac tggaggaagt ggacttggac tttatatagt
     8761 cagccaaatt tttaaaagtc atgggtttga ttatagcata aaaaacaaag aaaactctgt
     8821 agtattcaca gtagaattta aaaattaatt acttattata aagaatatat aactttcaat
     8881 aatagttcat tttaaaatca caaaaaattc ataatgaaac tgtattatat aaatataaag
     8941 aagcttaaaa ccataaaata caccaactat aatgatgaga tttccttaca tcctccatat
     9001 aagtcatcat tatagtaacc caacaattaa gttactatga atttaaaaaa taacaccgag
     9061 catataatct atgcttagtg ttatttttat tttgaaataa aaaatattta atttattgaa
     9121 atgtatagat ttagatagtt taaactatat ttaagactta aaaattataa ttgatattac
     9181 aaataaatat atgtactttg ggaaaaataa atataggaag tattatattt acagaggagg
     9241 tagttttgat ggatagatta aaaagagata tgaaaaatat gaaagaagat ttaaaagaag
     9301 gtgttaaaaa gacagcttat gttatgaaaa atacagctga agatttgaaa gatgatgcac
     9361 aaggtgctat ggtaaactta gaaatgaaaa aagatgagat gatggaaaga tatgaacaaa
     9421 agaaattttc taaagaatta gagaagcaaa tgaagaatga aatgaaataa gcttttattt
     9481 atgaataaca aattattgta ttcatataaa aagtagccag taatattaaa tagtttattt
     9541 aaggaaatag actttctaaa aataactgta ttagatttag aaagtctatt tcaaattagt
     9601 tttataaata gacataagga taaagtagat gttatagaac tagattttaa aaaatagata
     9661 ctaaggataa aataaatatt atagaaatat gtttttaaga atatttatca aataaaaatt
     9721 tatatttata agaaatccta taaaacatat aattaaactt ataaaacatt tacattaaat
     9781 tctgataaaa tatctactat atcaggagta ggcgtttttt ctgtaattat agaactaata
     9841 tcttctaaat gagcaaactt gaaatttcca tcaaatttaa actttttatc ttccataact
     9901 ataaatactt ttttacttga atttattata gccttcttcg taagaccatc ttcaatttca
     9961 aaagttgtaa gtgaagagtt gaatacatct actccacaac ttcccataaa agtcttatca
    10021 aacttatatt tcgatataaa ctctatagtt ggagtaccga caaaaccgtc taaactgaga
    10081 tttaataaac ctccagtgga aattatattt aaattatttg gttttgaagt aactacattt
    10141 agtatatcca gcatatttgt aacaagtgtt acttttttat tactttcagc taacaacttc
    10201 gcaagcaaga tgttaattgt agagatatct aaaaatatag tttctctatc ttcaattaaa
    10261 ttaaatgctt tttctgctat tattttcttt gttggaatat taatttcttt tctgtctttt
    10321 gtatcctgat tctctagtgt ttctctagct agtacagctc ctccataaat tcttcttatt
    10381 gaagaaatct tttctatatt ttttaaatct tttcttatac aatcttctgt aacattaaat
    10441 ttagaactga gctctttgac agtaactcta ccttcttttt ttaggatatt taatatagct
    10501 tggattcttt cttctgcaaa cattttctac ctcttttcgc aatatagtat tatagtaaat
    10561 attataagat aaaatacaat atatcaacta ttttaacatg aaatacaaaa ttaatttaat
    10621 ataaaaagta tgttttttct aactatatat ttagaattta gtaaataaaa aaattataaa
    10681 actaagaagg aaaagtaaaa caataataaa aaataaaaaa caataagcaa aatgttgaaa
    10741 ataataccaa atcaatatat aataagaata aagaaagatt aaagggggat attttaatgc
    10801 aactaatctt agatacaggt aatgtggagg agattaagga gttatgtact tgtttaccaa
    10861 tagatggtgt aactacaaat ccaagtattg tttcaaaaga aaaaaagaat tttaagcaac
    10921 ttataaatga aattggtgag attataggtg aggatatgcc tatacatgct caagtgttaa
    10981 gtacaaagta tgaagaaata ttagaagaag cattatatat aagtagtttg agaaaaaata
    11041 tatatgtaaa aatacctgta acacaagatg gtttaagagc tataaaagac cttcatagaa
    11101 aaggtgtaaa aataactgct actgcaatat tcactgctca tcaaggtttt ttagctgcaa
    11161 aggctggagc aaattatatt gcaccttatg taaataggct tgataatata tctggtgatg
    11221 gagtagctat ggtttcagaa cttataaaaa taatagatac ttataaaatg gatacaaaag
    11281 tacttgcagc cagttttaaa aatgcacaac aagttataga attaatgcaa catggggtgc
    11341 atagtgttac agtaccatat gatatttgta aatctatgat gaatcatcca ttaactgatt
    11401 ggagtgtaga taagtttata gaggattggg agaatacttt tggaaaagga agtaaaacaa
    11461 ataatattta gtattatggt aaaagagtag ttttgtccaa ttttacaaga acttatataa
    11521 aaagatgaaa atatgaattt tctttttaat aatttcgtta ttatcttaag ttaattcata
    11581 ttttcatctt ttttagattt ctagtcctat aaatttccac caagggaatg ttatacatat
    11641 tattataaag taggttaaag gaatcaaagt taaaccgtat ttgaaaataa ccttgctatt
    11701 atacagattt tcaccatgac caaccattat tgtagcatga tgaaatggta atatgtactg
    11761 tatgcttact ataatgtaga caaatagaca taaagtaaca ctattttcct ttagtatatg
    11821 taaacttcca agtaatggta ttactacaga tgatgtagtg acagcacttc caagacatat
    11881 attcaagatt attgtgagag ttatcaaaaa caatattgaa ataatttctg aagagtttgg
    11941 tataaacttt atcaaataat ttcccattat atctacaact ccagagtact ttaacactcc
    12001 tccaattgaa aatgctgcta taaaaaaaat aaggaccttc caatttattt cttttaaagt
    12061 actaaatcca actatttttc ttagtaataa aagaagtaca caaattgaca ttataattaa
    12121 tgtgtttatg ttatgtatga actgagttaa aaacataaaa aacattattc ctaggcataa
    12181 aaatacgtgt ttttgttctt tgtttagcaa attaaattct ttttttaaat tagaatatga
    12241 aaaatgaagt ttattaccct caagattttc attagaaata aattttattg aatgcaattc
    12301 ttttttaaag acaaaggtaa ataaaaaata agttataaaa caagtaatta tagttggaac
    12361 agacatataa aaagcccatt gaccccaatt tatattacaa tttccaagtt ctagtacaac
    12421 ataatttaga agagtgtctc catttacaaa aaacattgat gtaaaggtag atgctgtaaa
    12481 tatactaaat aaaagtatag attttgaatc ttcagttatc tgttgttctt ttaaaaactc
    12541 cttgtaaaaa gcagatacaa gaataaccct tggaaatggt tgtgggataa aaaatattaa
    12601 aagtatacct aaaatatacg ataaaagaat cattttttta ggggtattta cagtatttaa
    12661 aattaacttc tcagaaataa tttttgcgac acctgttttt gtaactgcat tagtaattat
    12721 gtatgcaaga attattatgt aaaaattttc tgtaaataaa aactgtaaaa taacctttat
    12781 tggtgcaatg ttaaatataa acgctagaat tacaaaaaac aatgcaacaa aagttttttc
    12841 aactgagtct acagcccata tcaagatagt taaaaaagat aagcatatag aaaattttat
    12901 gttgaaactg taattaagag agaagtagag aattatggta gctataacag tcatataaaa
    12961 ttgttttggc ttaagaataa tacccatttt tatattcacc tccataattt attatatcat
    13021 aatggaggtg aatacaatga atgtgaatac attttataaa aagattattc attgattcta
    13081 tgatttacaa tagctttagt tttccaatgt cctttcttat agtagataac tgtaacaata
    13141 agacctaaag tccaaccaaa aggaataccc atccaaattc cgtctgttcc aaaaaattta
    13201 gaaagcatat aagaagctgg aagtcttcca agccataaag atactattga gcttataagt
    13261 gcaaacatgg aatcaccagc acctttcatt gcacttgaaa gtacaaaaga agttccaata
    13321 aataagaaga atggtcctat tataaataag taagaagagc caattttaat gacatcttta
    13381 tcagtattga atagagcaat tagattttcc ctaaatagca aaattaaagc aataactgta
    13441 actgctaaaa ctaaggtcat ttttatagat tctcgaatgc cttttttaac tctttcattt
    13501 tctccagcac ctatgttttg agcaacaaaa gtagaaacag cagaaccaag attcataata
    13561 ggtaagctta taaaattttc tatcctaaga ccagcaccaa aagctgccat agcagatgta
    13621 ccataactat taactaaaaa ttgaagagcc atatttccaa ttgaaaacaa catttgttga
    13681 actccacttg gaagtcctaa tctaagtcca tctttaaata ttttgttatc atatacaatt
    13741 cccttgattt taaatttaag cacttcatgt tttttattta aataaattat acttattata
    13801 aatgatactg cctgagccat tatagtggca agtgcaacgc cctcaacacc cattcttagc
    13861 actacaataa aagttaagtc taaaactata tttagaattg tggctattat cagaaaataa
    13921 agtggagtta ctgaatctcc aagtcctcta agtattgcac ttactgaatt atatccagca
    13981 gaaaataata ttccactaaa tattatagta agatacaatt ttgattgagc aaaaacggat
    14041 tctggtgtat tcataagctt aagcattggg ccaccaaata ctattccaag aatacttatt
    14101 aatatagaac caataaataa aagtatatat gtagtatcaa tagtagcttt tacctttttt
    14161 aaatctcctg agccataaaa ttgtgacact aaaatagaaa atccaaggct aacacccata
    14221 agcgctgcca ccaataaaaa cattataggg ttagctccag agactgccgc cattgcttct
    14281 tttccaataa atctaccaac tattatactg tcagctgtat tgtatagttg ttgaaataaa
    14341 ctaccaataa gcataggcat ggcaaaaaag aatatggact ttccctcatg acctgtagtt
    14401 aaatctttca ccttattcct ccaaataaaa aaattattaa tttattatag tataatctta
    14461 acataaactt tatatccaaa ctataaataa attgtatcaa aatatcatat atttttttaa
    14521 aatgtaaaga atataattat aatttgaatt taataaatca atatttaata taatcgaata
    14581 ttaatacaaa atcaatacaa tatatacgta tatattgaca aaattaatta tataaattaa
    14641 aataatattc gtaaagaaaa attcatgttt tgtactgtat aacatataat tttgacaata
    14701 tgggtcataa gtttctaccg gaataccgta aatattctga ctatgtatac tattatttag
    14761 ttaattaaat atttaattaa ctgaattatg aaggatacgg ctcagcttat caactactgt
    14821 gtcgtttttt tgtaaaattt aataggaggt gttgttatgc aaacaacaaa cagtagtact
    14881 atgcagaaac tttttccaat tttgactaat aaaaatgtcg acatgaagaa ggaaataatt
    14941 gcaggagtaa ctactttttt aactatggct tatataatag ctgtaaatcc aaatatttta
    15001 tctgagacag gcatgcctgc aggtgcactt gttacaggta cttgtttagc agcagcattt
    15061 ggatgtattt taatgggtgt agttgctaac cttccttttg ctttagcatc aggtatgggt
    15121 cttaatgcat tttttgcata tacagtagtt ttacaaatgg gtgttccttg ggaagtagct
    15181 cttacagcag tatttgtaga aggtattatt tttatagtat tatcagtaag tggagttcgt
    15241 gaggctgttg taaatgcgat accaaaaaat atgaaattag ctgttacagg tggtatagga
    15301 atatttattg cacttatagg tctagttaac agtggaattg ttattggaga ccaagccact
    15361 cttatcaaaa tgggtagatt tacaccagca gtaataataa cttgtgtagg attaataatt
    15421 attgctgtat tagataaaaa aagagttaaa ggttctatac tttttggaat agtagtgagt
    15481 tcattacttg cttgggcatt tgcttttata aatccagagt atgcacaaaa attaggtata
    15541 tatttacctg gtggattatt taaattcgaa agtttagcac caatagcagg taaaatagat
    15601 ttaggatatg tactacatcc aacaaatata ggtggttttt tagtagtagt ttgtacattt
    15661 ttatttgttg atttttttga tacagtaggt acattagttg gtgtttgttc taaagcaaac
    15721 atgttagatg aaaaagggaa tgttcctaat gtaggtagag ccttacttac agatgcggtt
    15781 gcaactacag ttggtgcagg acttggagta tctacagtta caacttatgt tgagagttca
    15841 acaggagtta tcgcaggtgg aagaactgga tggacagcaa taacagttgg aattttattc
    15901 ttagctgcaa tgtttttctc tcctgtattt atagcaattc catcatgtgc tacagcacca
    15961 gctttaatat atgttggata tttaatgctt ggtacagtta aggatataga gtttgataat
    16021 ataactgaag gtgttccagc ttttgttact attgcttgta tggcattaac atatagtata
    16081 ggtgatggtt taactttagg tatattaact tatgttttcg taaatatatt ttataatata
    16141 tttggagcta aaaaggcaga agacaaaaaa catgtttctg tagtaatgat tgttctggca
    16201 atattattta taataaaact ttggctacta taataggtat tatttaaaat tttaatttaa
    16261 tataaaataa agggctgtaa tttattatca attgtgatga taaactacag ctcttttgta
    16321 tttgttgtat ttttgtattt attgtattat ttaataatgt ctattagttc tccattttgt
    16381 aaagttttag gtgtaattac tatattgaac tctttttgca aatcttttat aatatctaat
    16441 tctttttttg ttattattga gattgtgtta ccacttcgat ttcctctagc agttcgacca
    16501 catctatgca ggtattcatt tttacttttt ggaaaatcca agttaaaaac atgacttaca
    16561 tccacaatat ctagtccacg agcagataaa tcagttgtaa ttaaaatctt tgctttacca
    16621 agtttaaatt tatttattgc attctttcta tcttcttttt ccatatttcc aaaaattcct
    16681 attgctttgt aattatgata atttagtttt gatactagga cttctatatt tttttcatta
    16741 tttacaaata caatagcttt ttttggattt gtagctgcta atgcctttct aagaaaagta
    16801 aatttatccc ttatctcacc taataaatat gagtgattga tgttaggatt tatttgtgat
    16861 ttttcctttg tttttattat ttcaaactcc ttcataagtt tatcacaaat ttttatagtg
    16921 ctatcagtaa gacttgcaga gcatcctata atttgtctat ctcttaacgt tgttcttatt
    16981 atgtcttcta tacaagttat attttttcca ttcaatagat tgtccacttc atctaagaca
    17041 atagttttta tattatgtga ttttagtttc ttttgtttta tcaagtctaa aactcttcca
    17101 caagagccaa ttactatgtg tggttttact gcttttatat tttttatttg tttttgtata
    17161 ttgacctccc caattaaagc taaagaagta acggagagtt ctgcattttt agccaataat
    17221 tcaacctggt ttgtaatctg cattactaat tcatgcgtag gtgcaagtat aagagcttgt
    17281 gtttctcttt ttgatgtatc aattttttca aatataggta aaaggtacgc tagtgttttt
    17341 cctgttccag tctgtgaatt aatcaataaa tccttatttt gaattatatt ccctataaca
    17401 agtgactgaa cttctgttgg agaagttatg tcttgttttt tgagtccatc tattagagtg
    17461 gaacttattt ttaattgttc aaatgtattc atattttact ccttatattt taataattat
    17521 agtcaactat tttttattat acattgttta ttcaaatcga actatatatt cttttataat
    17581 tatgtgtaat ttgaaagtaa atatcaatta tatttatacc tttatatttc tgataccttt
    17641 gcattttata gatttctaaa ataaacaaat aaaagttgta attgtttgat atttgttata
    17701 tattgtatat aacaaatatc aaaactataa tatggaggga aattatgtta aaagtaatca
    17761 atgtatctaa atcatataaa aataaaaaag tagtaagtag tgtctcattt gatgtaaatg
    17821 atggagagct ttttgggttt ataggacata atggagcagg taaaactact actattaaag
    17881 caattgttgg aatacacgat tttgaagagg gagaagtact aataaattct aaatctataa
    17941 aaaaacagcc tgttgaatgt aaaaaggaaa tggcatatat acctgataat ccagatttat
    18001 acgagtcatt aactggtata caatacctta attttatagc tgacatattt gaagttgcca
    18061 aagataaaag agaagagtta ataaaatatt attcaaataa gtttgaactc aataaagcat
    18121 taggagattt aatatcttca tattcgcatg gtatgaaaca aaaattagct ataatttcgg
    18181 ctttgataca cagtccaaaa atcttaattc ttgatgaacc ttttgtaggt cttgacccaa
    18241 aagcttcctt tatattgaag gaaattatga gggagttttg tgacaaaggt ggttgtatat
    18301 ttttctcaac acacgtttta gaagttgctg aaaaaatttg tgataagatt gccataataa
    18361 aagatggaaa tataattgct tatggaacta cagaagaagt taagggaagt aattcacttg
    18421 aaagtatctt tatggaatta atagagaaat aaaatgtttt ttatacaata tagtgtctaa
    18481 agtgaggaat gataaaatat gagcaatcta agtatattaa taaaaactaa tataataaat
    18541 gaatttaaat taaatgcgtt aaaaaaagct gatggtagag aaaaacaaaa aataatggga
    18601 atgatgcttt cagttgttat aatagcgggt ctattaattt tttatgtaac aagcttaagt
    18661 ctctctttag ttgatatctt aaagcaaata aatcaactgg aaatgctact gatatttggt
    18721 tttggattat caacattaac aactattgtt acatcattat ataaaacgtc atcatatcta
    18781 tttcaagcaa aagatttaga ccttttgact agtttaccta taaaagaatc tactgtacta
    18841 gcaagtaaga tattaatgtt ggttggagca aactatttat tttcttcaat atgtatgctt
    18901 atacctgcag tggtttactt tttaaattct gatgtaagta taacttattt cccttatttg
    18961 atattgctat ttttagcttt accattatta ccgatagttg cttcatcaat aatttttcta
    19021 tttatagggc agatatcatc aagaataaaa tacaaaaatt tagtattaat cataggtagc
    19081 attatattga tgttgcttta taccctactt atgtcaagac ttaattctat gtcagttgaa
    19141 atgctaaaga atagtgtgtc tatttcagag acgattagaa aagtatatcc tcctatatat
    19201 tattttgttg atgctcttaa aacaggaagt atagtttcat ttttagcatt tatagccatc
    19261 tcaataatac cattttttat gtttgtaact ctgtttgcaa aaaaatttaa agatataaat
    19321 gctaagatga gtgaaggata taagtcaaaa aattatgaat ttaagggtca aaaaacttca
    19381 agaccttcaa aagctttatt aaaaaaagaa tttaagagat atacttcttc gtttatatac
    19441 tttttaaatt catctgcagg tttgttattt ctaatagtag gtacaatttt aatattatta
    19501 tttggagcag ataaagtggg tgagttactg aaattgaata tagattttaa tcttataaaa
    19561 atacaattat tgggagtatt cttctttata atagtaatga attgtacaac atactgttca
    19621 atttctcttg aaggaaaaaa cttatggata ctgaaatctt ctccaataga tgaaagagaa
    19681 atattctggt caaaaatatt gatgaatttt ttattgaatg caccactatc tattttatgt
    19741 ctaatattag tatctataag attagacttt gaaattcagt ttattattgt atcaatctgt
    19801 ttgattgtaa gtttttcaat gtttgtagca ttgatgggat tattatcaaa tttattatac
    19861 ccaaaccttg attggaaaaa tgaggtggct gtagtaaaaa gaagtgcaag tatgatagtt
    19921 acaatgttag tatcattagc ttatgtaatt atacttggag gtatatatgt attacttgga
    19981 atttcgtttt taaatatata tattattttg gcaagtatac ttactttgat attagatttt
    20041 atgatatgga gaattatttc tactaaagga gtaagaatat ttaaaaattt ataggtgtat
    20101 ttatgtcaaa taaagactta tcttttttag tcttgcaaat aataggttaa gtagtatact
    20161 atgtatagtg atatgaaaaa atttaggaga aaataaatga gaaaattatc caaaagagaa
    20221 aaagatttta ttcaatatgg atttttatta tttttgatat gtattactac ttatttagta
    20281 ttaactactt tagatataaa actaatacct aaaattataa ggctagtaaa taagacttat
    20341 atatttcttg gcatattgac aattatagta tatatgataa ttgaatctat tgtaactcat
    20401 ttgataataa atgcagttca aaaaacaaaa gtaaaattta ttggtattaa aatggctaca
    20461 atgggatttt actataactt agttactcca tttgcatctg ggagtcaacc aatgcaaata
    20521 tatgcactta caaaatatga tgtaagcctt agtaaatcag tggctatagt tactaataaa
    20581 actgtagtat ttcaaagtac agttactgta ttttgtggaa ttttaatttt gctaaataag
    20641 tcattactga tggagcaagt acattctgtg aaagtcttga taacttttgg aatgattatg
    20701 aatgtaagta tgttgttagg tggactacta atagtattta gtccaaaaca agtaaaaatg
    20761 atagcagaag ttttgattaa ttttttatct aaatttaaaa catttaaatt tttagattca
    20821 aaacgtgata gaataaatca ttatattgat gattataatt attctataaa aatatttatt
    20881 aaaaatgtaa gaatcttagt tttaagtata ttacttactg tgttacaatt aatcgcatat
    20941 ttcagtatag tttattgtgt gtataaagcc tcaaatttaa gaggagtttc atatgtacat
    21001 ataatgacat tacaggtctt tttatatatg gctatatcac caattccaac accaggaaat
    21061 gttggagcta atgaggttac attttttact atgttctcca atataattcc aaaagaatta
    21121 ttggggtact ctgtactctt atatagtggg tttgtatact attttatatt aatagtttca
    21181 ggtttattta catttggaac gcattataca ttaaattctt ggaaaaagga aaataaagta
    21241 aattctaatt tagataaggt tattgaaaaa ttaaattaat aaaataatta gggaaattct
    21301 atatataaat atggtgttga ataagctata ttatattgag atatttccct tttttgatta
    21361 aaattataga aatttgaaat aataagtaat aaacagaaaa agtgatattg ttttgaaagg
    21421 agaaactatg aaacaagata aacaaaatga aaaacaaagt gagatttcta agataaaaca
    21481 aagcaatgat aataaacttg aaatagctca agaattacat gtaagtaaaa atatagggaa
    21541 tatgcttgga tatagaatag ataagaaaaa aatgaataga ccaagttaat gaaaatgttg
    21601 aaaatggtac attttaaaaa atatatataa tgaaatgttt tattgttaaa tttaaactta
    21661 ttttaatggg ggaaaaagtc gaaaaatatc taaaaagata tggatataaa aaatattaat
    21721 atatatatac tataaacttg acaaaatcaa ccttttaata actagcaaaa aatagcaaaa
    21781 ttatataagc gttatttaat tgtcaaaaat gaaagctaaa ttgcatgtcc taaaaaaaat
    21841 gattgataac atttatttgt gtgctataat tatatagtaa aacaataagt atattgcata
    21901 atgtatgcaa atcgggagga gagacggaca tggaagcatc tatacacaca attgccagca
    21961 ataatttatt gataattttt gctattgtaa gtataactgg aataatttgt agtaagctta
    22021 gtgaaataat aaaggttcca gatgtagtgt tatatttact tgtaggtatt ttaataggac
    22081 catcattttt aaaatttata gatattcgtg gatttcaaat agaaaatcaa ctaatactta
    22141 catttggttc tgcatttatt ttatatttag gtggaaaaga aataagttta aaagtattga
    22201 gaaatgtgaa gatatctgta ttcttattag ctactttagg agttgtgata tctgctttta
    22261 taatgcaaca agtaatagga tttacttttg ggataagtgc aatgactgct ttactagcag
    22321 gaactataat agcatcaaca gacccagcca ctcttgtacc tatatttaat caggtaaaga
    22381 taaaggatag ggtaaaacaa actgtaataa gtgaatcagc ttttaatgat gcaacaggag
    22441 ctatactaac atcagcagtg ttggctgtaa ttttgtcaaa taaattttca ttaggtgaaa
    22501 atatttatga actggggaca atggttattg tcggagtttt agttggttta attacaggaa
    22561 tactgctttt gaaattagtt aatgataaac cttatggaat atttaaagat tttgcaccaa
    22621 taatatctgt tatttcagtt gtagttgcat atgaattatc tacaaaatta ggtggaagtg
    22681 gatatatgtc ttgctttatt gtaggtataa taactggtaa caagaaaaac tttaaaattt
    22741 ggttaagtca aaaatcttat gatgcagatt tttatgttgc tgaaacttta ggtactattt
    22801 gtcgtatggc aatatttata atattgggta gccaagttaa tttggctcag ttaagtaaat
    22861 attttatgcc atctgtaatt acagtattag tattaatgtt tatagcaaga ccactttgcg
    22921 ttttagtttg tacacttgta gacagggaag caaaatggag taaaagtgaa atattattta
    22981 tgatgtgggt aagggaaaca ggcgtaatac cagcagcact ttgtggtatt atttcagcaa
    23041 tgaaagttcc tggatacgaa gtgatttcat ctgtagtatt tatgactata ctaattacat
    23101 tagtaataca aggaagtact acaaaattag tagctaaaaa acttggatta ttagaagaag
    23161 aagtgataaa tataagtgaa aaagtatcaa ctttttaaag ttttgcttta aaatagtacc
    23221 tgttaatggc tattttaata ttgtctaatg atgattattg aaatagtcat ttttttatgt
    23281 ataagtaatt tacagaattt acatattaga catatttatt atcaaaattt gttgaagcta
    23341 tgatataatt agttgtattt aaaataagaa tagcaaataa gggaggaaat ttatgtttac
    23401 ggttatggat attgtacagc cagatacagt agaagaagcg tactcaattt taaataaaag
    23461 aaaaactaac caagtaattg gtggaagtgc ttttttaaga atggggaaaa aaagaatagg
    23521 aacaggaata gaattatcta aattaaattt agattatata aaagagtatg aagattacgt
    23581 tgagattggt tctatgacta cttttagaac attagaaaca agttccataa taaaaaataa
    23641 ttttggaaga ataatagaag attcagttaa aaatataata ggagttcagt ttagaaatgt
    23701 agtaacagtt ggtgcaacag tattttctaa atatggtttt tctgacttga tagtagcatt
    23761 actttcatta gatacagaag tagaattata taatattggg agaattagtc ttgaagagtt
    23821 tctaaataga gattatgaga aagatttact tattaagata tacataaaga agacaaataa
    23881 gaatgcttct tataaatcac ttagaaatgc aaagagtgat tatccaattc taaatgtatc
    23941 tgtatcaaaa catatggaac aatttaagtt atgtgtagga gcaagaccgc agaaagctac
    24001 gattgcaaaa caagctagtg aatttctatc taacaatgaa atcaatgaaa ttaatataga
    24061 taaagcagta gaaatagcat cagaagaact aacttttggt tctaacatga gagcatctag
    24121 ggagtataga aaagctatga gtaaagtact tttaaaaaga gctataatgg aggttattta
    24181 atgttagtaa agattaatat aaatgggaag aaaaaaagtg ttgatataga accagaagaa
    24241 tatctggttg atactttaag aaaagttggt aatttaagtg tgaaaagagg ttgtgacaca
    24301 ggctgttgtg gtttatgtac agttttaatt gacaagaaac ctacattatc ctgtgcaaca
    24361 ctgacattga gagctttaga taaagaaata actacaattg aaggtttaga aaatgaagtt
    24421 aaagaattta gtgaagtttt ggtaaaagaa ggagctgagc aatgtggttt ctgttctcct
    24481 ggctttatac ttactgtact tgcaatgaag gatgagcttg aaaatcctac agatgatgaa
    24541 ataaagcatt atcttacagg aaatctatgt agatgtacag ggtatatggg acagttaaga
    24601 gctatcaaaa cttatctgga ggtaaaatag aacatgaata tagttggaaa aggaatcaag
    24661 aaaatagatg gaatgagtat cacaacagga aagcctgtat atacagatga tttatcagca
    24721 aaagatgctt tggtggtaaa gatacttaga agtcctcacg cttatgcaaa aataaaagat
    24781 atagatacat caaaggcaga aatggttgat ggtgttgaat gtgttttaac atataaagat
    24841 gtaccaaaat ctcgatttac acttgctggt caaacatatc cagagccatc tccatatgat
    24901 agattaattc ttgaagatgt tgtaagatat gtaggtgacg aagtagctat agtggcagct
    24961 atagatgaaa aaactgcaat taaagcaatg aatcttatca aagtaaagta tgaagtactt
    25021 acacctgttt tggattttga agaggcaata ggaaataaaa ctatggtaca tgatgaagat
    25081 agacattgta actttgatat aggtatgcaa agagaaaaaa atatagtatc ccatcatgat
    25141 tatacaaaag gtgatgtaga aaaagtatta agtaattgtg atgtagtgat tgaagaaact
    25201 tattatactc aagctcaagc acatgcaatg atggagacgt atagggcata caattattta
    25261 gaccatatgg gaagattggt tgtagtaagt tcaactcaaa taccatttca tgtaaaaaga
    25321 catttatctc gtgcactaga aataccagct agcaaaatta gggttataaa acctagaatt
    25381 ggtggcggat ttggtggtaa acaaactgca tgtgttgaga ttttttctgc aattgttact
    25441 ttaaaaacag ggaaaccagc taaaataatt tatgatagaa aagaaacttt taattgttca
    25501 acaagtagac atgcaatgag attaaaagtt agactaggtg ctacaaatga tggcataata
    25561 aaggcaatag atataaaagc actttctgat acaggagcat atggagagca tgcttctaca
    25621 actattggtt tggttggaga aaaaacttta ccaatgtata ataaagttga agcaacaaga
    25681 tttattgcag atgtggtata tactaataag atgccagcag gagcacttag agggtatgga
    25741 gcatcacaag gatgttttgc tgttgaatca actataaata tgcttgctaa taaattaaaa
    25801 atggacccaa cagatttaag gttaaaaaat gtggtaacag aaggtgaaac tacatttgca
    25861 tatggtaaaa ctttaaatag tgtcgattta ataaaatgta taaataaagg caaagaactt
    25921 attggatgga atgaaaaata tccttgtaaa catcttgata atggaaaaat tagaagtgtg
    25981 ggtatggcaa ttactatgca aggttctggt atacaaggtc ttgataagtc ttcagctgaa
    26041 ataaaattga atgactgtgg agattatact cttatgatag gttctactga tatgggtaca
    26101 ggaagtgata cgattttagc tcaaatggct gctgaggttc ttgatacaag cattgaaaat
    26161 ataacagtta tatcagctga tactgactta gttccatatg acccaggttc atatgcttca
    26221 agtactactt atgtaacagg tatggcagta gttaaggcag ctcaagactt aagagaaaaa
    26281 ataatttctg ctggagcaac taaactaggt gttgagaagg atgaagtaaa atttgatggt
    26341 ataaaattaa ctagtaaaaa aggtagcact ttattattcg atatagcagt tgattctaca
    26401 attggtccag atactaatca attaataggt cttgcttctc atggtagccc agtatctcct
    26461 cctcctttta tagcaggttt tgcagaaact gaaattgaca cagaaactgg aaaagttgat
    26521 ttagtaaatt atgtagctgt agtagattgt ggaacggtta taaataaaaa tctagctaag
    26581 atacaagttg aaggtggaat tgttcaaggg attggaatgg cattatttga agaagttaga
    26641 tacacagaaa aaggaagaat ggacacaaat acatttatgc aatacaagat tccagctaga
    26701 tgtgatattg gaaatgttaa agtagatttt gttgaaactt atgaaccaac tggaccattt
    26761 ggtgctaaat ctgttggaga agttgttata aatacacctt taccagcaat acaagaagct
    26821 gtgtttaatg gaattggtgt aagaataaat acactcccta ttacacctga aaaagttttt
    26881 atggaaatga ataaataatt atttatgaaa atttagacta gttttacatg ttaaacaacc
    26941 agttatgtca tacctgttga aagatattta ataagtagtt attataatat tatgaatttt
    27001 acttataaaa tacaaaatta aataagggga tgatgttttg gctggtaatc taaataatat
    27061 gagagcagta aataatttta gaggagataa gaacatttta gaatgtttag tcagctttga
    27121 gggtcgttca ataagtcaga gaaaagtaag ggtatttttt aaagaaaaac aaaatcaaat
    27181 agaaattgat tttgcagaag aggaaatttc taaattggtt gaaaatgttg ttttaaatac
    27241 atcatatcaa gaaatgttat atgatgaaat agagaaacaa ctggaaattg attgtatagg
    27301 tacttggatg atattatcta aattaaaaga tggtagtaga gttcactgat tttaaaataa
    27361 attattagag cctaatttta aggctctttt ttgctgtttt taattaacaa tagaaaactt
    27421 atctttagtt tgtatataat tttaatatca tatattctat atatataaaa ttgaatttgt
    27481 atgtattata ttgtataatg taaaatgaat tggaaaaata gttcgataaa ataatttgtt
    27541 tttataaaat tactgtttaa gtttatagat tttgtataaa ataaagttat gttattaatt
    27601 tttttagaaa taaaactttt actaggagac agatatgaga aaaaatagta ttaatatagc
    27661 actaactgca gcaattacag caatctatgc agttttaaca ttatcattgg gatttataag
    27721 ttatggacca atacaattta gggtagcaga gattatgatg cttttggcat ttttagataa
    27781 aggatatata gtaggtctta cattaggttg ttttttagca aatgtaatag gaccatatgg
    27841 tgtacctgat ataatttttg gaacattagc cacatttata agtgcaagta tgatttatat
    27901 tactagaaag ttaggtaaac agaataaaag tactttagtt atagcttctt tatggccaac
    27961 tgttataaat tcgattgtgg ttggtctaat gttaaatgta ttctttgggc ttccattaat
    28021 tctatctatg atacaagtag gttttggaga atttgtagta gtgacaattg taggagtacc
    28081 atttttctgc tttttaatga aaaaatataa aaatgtcatt aatattaaat tttaaatagt
    28141 gtatagtaat ttaattaatt gagagtatta ttagtgaaaa gaggtgttta tttgtcgaag
    28201 gtaaaaagat tgactgatgt ttggatatat attaatgata agcaaaagtt tacaataaaa
    28261 gagttgtcag aggaatttaa tctttcagct aaaacaatac aacgatattt aaaagaatta
    28321 aataaaatgg gacttccaat tcaagcagaa caaggtagaa atggaggtta tagggtgcta
    28381 aataatagct atatacctcc tgttatattt acagaaaaag aagttatgat tatactattt
    28441 gcacttaagt cacttcagat ttataattat aagttaatgg aaatagaaat taattctata
    28501 atgagaaaag taagttatga acgtaaaagc agtataaaag taggtataga aaatattaaa
    28561 agatacattg gctttgtagc taatgatact aatgatggag attttaagag tagtaatgta
    28621 actgagtttt ttagagcttc ttcagaatct ctaattttaa atattaagta taagtgtggt
    28681 aatcagattt tggaaaaaaa cgtatgccct ataggtatat atttaaataa gggagcatgg
    28741 ttttcaccag catatgattg taaaagtgat aaaataatat tagttcatat agataatata
    28801 attgatataa aaagaacagg agaaagtaaa aaaatacata taaacttgga agaatggtta
    28861 catgaagtat ataacaattt atatggaaat agttcaacta ctaaaaaatt tggtgaaatt
    28921 atttatctaa atgtattatt aactaaagaa ggtgtttcta aaataaagga cagttcttgg
    28981 aatttagata tggagctaaa tgaagatggt agtggaataa ttagtacatt cataaaggtt
    29041 gaagatatag attgttatgc ttcgatttta ttttttattg gaaataatgc taaggttata
    29101 gagccaaaat ttttgaataa gctactttat gataaggcca atgagttaag atatttttat
    29161 gaagaaaata tggtataata tttagaaatg ttgaaattaa ataattatta aggagatata
    29221 cgttataatg gaaaatttta ataagaatgc taaaataatt ggtattggag ctgaaggtat
    29281 taatataata aatgaagtag aagaaaaaat aaaagcaaat atggatatag aaaaaataaa
    29341 cataaatcaa gagattgaaa aagaatatgt tagaagtctt ttagatggtg tagatatatt
    29401 atttttgata tattcatctg aagataaaca tattagagat attataaaag ctgtttcata
    29461 tatgtcaaac gaaagaagag ttctatctat aggaatggat tgttcagaga aagaaaataa
    29521 agaagattta gagcttggga gagagtttaa aatcaataat gatagtatat ttaaatttgt
    29581 tgatttaatg aatatcatgg tagagtctat ttctgattct tgcatgataa atatagatat
    29641 tactgattta aaagaagcta ttgtaggaga taaaggaatt aagtattctt ttgaagagtt
    29701 tgaagataca aagtcatata gcgagatagc tgacatttta tttgacagga tggaatatat
    29761 tggtgaggaa tttataagta agaaaggaat tgtatttgtt gaaggaagtc cagaattttc
    29821 tataatggaa ttgaatgatt taataagtaa tattcagagc aaggtagaag aaagctatga
    29881 agtaatattt tctttatata taaaggaaaa tttaaatgga aatattagag taggcttatt
    29941 gtataattag tatattttag atattaagga gagtgtatat gtctgaaaat ataagaggta
    30001 cagagtattg gttaatggaa gaattttttt atcaggaaac agacacacca cagattttta
    30061 gagaagaaag cataattgca cttggatttg acataaaaat aaatttaaaa aaagtattca
    30121 gtatggggaa aaaatcagaa aagtatatta atgagaattg taatgataaa gattttataa
    30181 aaaagtttat gtcgattaaa aaaggagatt attttttata taaagcatat caaaatatag
    30241 aagaaaaagt taaatgtaat gtgtctattg gcatagttga agaagatttt gaaaatggat
    30301 atgaattaag tcatatttta gggcatacac taccagtaaa atggatgcat aattttgata
    30361 cagtttcaaa ttgtaaagta tatacaagtg aattttataa attaaataat aatgatatta
    30421 gctcatattt agaaattatt aagtcacaag ataagaaatt attgagaaaa agaatagaag
    30481 aaagtgaaaa taataaatgg tatttaaaaa actattatta taaaaatgta gataagtgtg
    30541 tagatgatga agaattattt attcagccca ttaatctaga acaattagaa agcctaaaaa
    30601 atataaagac agatgattat attttattgt ataatagcga gaaagtaatt tgtgaaaatg
    30661 accatacaat gaagagtcta tttggcgtat gtcaagttat ggaagggttc gataaagaga
    30721 aagtaagtgc tttggaaggt ggatattttt ttcctgttag atggatagag tatgaaaagg
    30781 agaatataga cggaaatgca tgggttatat ttgaaaataa tagtatagtt gaaaagtatg
    30841 taaaaagatt tactaataaa atgccattaa atactatact ttatggacca ccaggaactg
    30901 gtaaaacata caatacaaaa cagatggttt acaatctagt aagtgaaacc agtctaagaa
    30961 acaaatacta tacaggttac ttagattata aaaacaatgt agaattttgt acatttcatc
    31021 aatcatatgg atatgaggaa tttatagagg gtcttaagtc tgatggtgaa ggcaatttta
    31081 agcaagaaga tgggatatta aaggatatat ctatagaagc atgttataat gcattgaaat
    31141 ttgaaaaaaa gatgagcttt gagttggaaa aagatagctt gactttagaa actataaaag
    31201 acaggaaaaa gaaattagta ttagaaaata tagaatatag tgagagtttt aattttgaag
    31261 aatcagaaaa ctatgtttta ataatagatg aaattaatag agggaatgta tctaaaatat
    31321 ttggtgagct aataacatta ttggaagatg ataaaagact tactaaatca aatcaaacta
    31381 ttgtcaaact accatattca aaggaaaaat tttctctacc tccaaatttg tatatagttg
    31441 gaactatgaa cacatcagat aaatcaatag cacttttaga tatagcttta agaagaaggt
    31501 ttaattttga agaaattatg ccagattatg atttattgtc tattgtagat ggtatagata
    31561 ttagaaaaat gctatataca atcaataaaa ggatagagtt tttatatgat agagatcatg
    31621 ttattggaca agcttatcta cttgctgtag aaaatattaa tgatatagta gtagtattta
    31681 gaagtaaaat aataccactt cttcaagagt atttttatta tgattcagaa aaagtaggtt
    31741 tgattttagg aggaattgga agaaatgaaa aagataaata cattgtttat aaagaaaaac
    31801 ttatagcttc tgagttattt aaaaataata atgcctcaat aatggagagt aaagttaact
    31861 attgtataaa acaaaacata tctagtgagg agctaaaaaa tatatatgag taaaaatata
    31921 tatgttaagg aaacctatga atggataagg gtaggtaatg gtgaaaatga gcttacagaa
    31981 attgaatatg aaaaattgct taaatatcta gagaacaata atgatgtatt aaaaagtaat
    32041 ataatagata ttaaatacaa aaaacttaga tttataaact atgtaggcat catatgtttt
    32101 gaaaatgtaa tacttgaaat acttcctaaa ttgtcattaa gtgataatct tgtaaaagat
    32161 agagagatac tattacagat gctttc
//
LOCUS       DAEPHU010000046        31966 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 01A10CD0081
            SAMN05941466-rid12468953.denovo.046, whole genome shotgun sequence.
ACCESSION   DAEPHU010000046 DAEPHU010000000
VERSION     DAEPHU010000046.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941466
            Sequence Read Archive: SRR6291087
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 31966)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 31966)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068158.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 22:43:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,892
            CDSs (total)                      :: 3,805
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 87
            rRNAs                             :: 8, 1, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 55
            CDSs (without protein)            :: 55
            Pseudo Genes (ambiguous residues) :: 0 of 55
            Pseudo Genes (frameshifted)       :: 21 of 55
            Pseudo Genes (incomplete)         :: 28 of 55
            Pseudo Genes (internal stop)      :: 16 of 55
            Pseudo Genes (multiple problems)  :: 8 of 55
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..31966
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941466-rid12468953.denovo.046"
                     /strain="01A10CD0081"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            complement(<1..719)
                     /gene="yqeC"
                     /locus_tag="KR231_002257"
     CDS             complement(<1..719)
                     /gene="yqeC"
                     /locus_tag="KR231_002257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative selenium-dependent hydroxylase
                     accessory protein YqeC"
                     /protein_id="HBH0004624.1"
                     /translation="MELSNIIEKNEIITVVGAGGKTSFINYFANFYRDKLKVLLTTTT
                     KIYVPNDYDNIIITIDGTVIPSICHGITVCGSYINNENKLVSIDSSILDEIVDQFDLV
                     LIEGDGSKRKKLKGWNAKEPVVYHKTTKTIGILDITSFGMNINEENIHRVEIFKKIAN
                     LDTSSINSSSTVSIENLKNIVLNPNGLFKNYSGKRVLFINKVENEKYKNLAIKLVENI
                     KEYESEIEIFYGSVKQKFCVR"
     gene            complement(902..2179)
                     /locus_tag="KR231_002258"
     CDS             complement(902..2179)
                     /locus_tag="KR231_002258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HBH0004625.1"
                     /translation="MSNRIKNIHYGTQRQQLKNLTKKEYQALREMCFLAKNLYNVGTY
                     NVRQHYFNQGEHLNYEANYHVCKENENYKLLNSNIAQQILKEVDSSFRSFFGLIKLAK
                     EGKYDFRGIKSPKYLDKEGFFSIIIGQIRIKEDGILNVPMSPAFKKLYGKVSIKVPQN
                     ILEKKIKEIRIIPKHKARFFEIQYCYEIPKSEEVSNQKNALAIDLGLENLCTCVTNLG
                     DSFIIDGKRLKSVNQWANKQNDKIEALKLKKNITAITRKQFKVWNKRNNQVKDYVNKT
                     CFYIIDYCVKNNIGNLIVGYNAKLEKSDNMERKIYRNFIRIPFGEIKGKLEYLCKIKN
                     INFIRQEESYTSKSDFFADDFLPDINVDNVKKYDFKGERITRGQYKSSVGIIINADVN
                     ASLNILKKSQVVNLSNLQNNPQILKQPQRVRIS"
     gene            complement(2318..4624)
                     /locus_tag="KR231_002259"
     CDS             complement(2318..4624)
                     /locus_tag="KR231_002259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdopterin-dependent oxidoreductase"
                     /protein_id="HBH0004626.1"
                     /translation="MINKGIRKIDSTAIVTGKPLYTEDLIMHKDVLTLKLLRSPHAHA
                     KIKNIDTSKAEKIPGVVGIYTYKDVPQVRYCVPGQTEPEASPYDRVLLEDTVRFIGDE
                     VALVAAEDEKTALKALKMIKVDYEVLKPVFDAREAEGNEVVIHPEKDIVEPYPFGLDA
                     KNNIVSKEFFEFGDVEAKLKESDFVVESSYKTQSQSHCMMETHRSYSYKDINDRIVVV
                     SSLQSPHNVKRILRKVLGIPSSKIRVIKPRIGGGFGGKNIAATDIFTAFVTMKTGRPA
                     KFVFTRSETFVGSNSRHEMFFDVKVGADKEGNLKAIELKSLNNTGAYGGNGVSVSSES
                     GHNTLPIYNDIDAVRFNARTVYTNRLPAGALRGYGATQGIFAIDSAIDELAHKIGMDP
                     LEFRIKNIIDRYTNGKAAEDEILSCELRQCIEKGKKLINWDDKYPCKDIGNNKVRAVG
                     MAVANHGSGIPRVDMATVTIRMDEDGTYKLLSGLADLGQGADTIQAQIAAEALNTTVD
                     RISIYTGDSDLCPYDTGAFASCTTTVTGNATIKTANKLKDILLSVAESKLGFKKEDLE
                     LGKDRVFVKNDNSKFVLLEELGRESVGGIGFASDDVPVVLEATESFGMLKKIKPFIAG
                     FAEIELDKNTGEYKVINFACVPDCGTVINPTLARIQVEGGVMMGIGFAMYEDPIFDKD
                     GRLLTDSFLQYKVPTKKEVGNILVDFAENFDPGGPYGAKSLGEIVIHTPAPAIANAIF
                     NATGVRLRELPMTFEKVYMGMKNNNKQL"
     gene            complement(4617..5411)
                     /locus_tag="KR231_002260"
     CDS             complement(4617..5411)
                     /locus_tag="KR231_002260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD binding domain-containing protein"
                     /protein_id="HBH0004627.1"
                     /translation="MVTIKEYSVPQSLEEAYKILISKKNNVILGGCGFIKLSNKNIGT
                     AIDLKDINLNYIKEDKKNILIGADTSLRSLEIDKTIKNYCSGILSSAVSNIVGVQFRQ
                     GARIGASVFSKYGFSDLIPALLVVGAKVRLYNKGILELSEFLDSELSRDILVEVILPK
                     KDAIAVFDSIRKCTGDFSVLNSAMLKENDTYKIAIGARPQKARLALEASNILNKEKDI
                     DKASIVASKELTYGSNMRASKEYRKDMASALVKRMYNAIEEGMYND"
     gene            complement(5518..6876)
                     /locus_tag="KR231_002261"
     CDS             complement(5518..6876)
                     /locus_tag="KR231_002261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine/pyrimidine permease"
                     /protein_id="HBH0004628.1"
                     /translation="MKAKSTSKFELDGIPPLKEAIPLGLQHLMAMVIGSCLPAILIAN
                     AAGLNHKMSTLLIQAALVFAGLSTLLQLYPIPLFKGFKLGGGIPVIMGATAMFIGAGV
                     SVASKYGLPVLFGSQIIAGIVIIIIGFGLKKIRFIFTPAVSGTIVACMGLGLFPIAIK
                     NLAGGMGNETFGNPINFIVGISVSLMILGLNKYGKGLFKDASILVSIIFGYILSLILG
                     IVNFSSIQEFTLVALPKPLAFGLDIRLEVVVMFSIIYLVEIADIMGACTLSAVGGLNR
                     QVTDEELSSAVLGNGVLSTIGALFSATPMGMFGQNSAIVSNTKVVSKFVLAIGGIGLF
                     LAGISPLLANLIRTIPPCVVGGATLVIFSTLTTSGLRLVSMDGFNQENSMILGLSMAS
                     GIGFMVAPQVLEKFPKFIETLLADSSVVSGAMVAIIIQALYMVKFPGNKSDKVEDKNK
                     SL"
     gene            complement(8224..9231)
                     /locus_tag="KR231_002262"
     CDS             complement(8224..9231)
                     /locus_tag="KR231_002262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0004629.1"
                     /translation="MVMQVQEKILELLYTINEDVVSIKNDMSEVKQEINVLKEDMSEV
                     KQEMTVMKEDMSEVKQEINVLKGDMSEVKQEMTVMKEDMSEVKQEITVMKEDMSEVKQ
                     EINVLKVDMSEVKQEMTVMKEDMSEVRQEINIMKEDMSEVRQEINTMKEDMSEVRQEM
                     TVMKEDMSEVRQEMTVMKEDTSEVKQEINVMKKDMSEVRQEITVMKEDVSEVKSEVNF
                     MQNKINNINEDMNGIKDEVSIANEKLYGIEIKIDSLECEDKSMKEIQIEQNNILGSLL
                     HNSEINKATHDNIEHNIAYIKGDTNSIKEDIAEIRRDLNLVELATSKNWSDIVKLKSV
                     K"
     gene            complement(9461..10546)
                     /locus_tag="KR231_002263"
     CDS             complement(9461..10546)
                     /locus_tag="KR231_002263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase"
                     /protein_id="HBH0004630.1"
                     /translation="MYNFLGKELKSPLIIGSGPLTYSAAGCKILSDAGAGAVVTKTIR
                     KERAINPAPHMVRNTANALLNNEKWTDFEPEQWIDFEIPQMKRDGTVCIASVGHTIEE
                     SSELVEKVANAGADFIELVSYDYRDLIPMLKDAKERVNIPVIVKLPPMIDEIGDFAKK
                     LEEAGADAITACDSVGPAFRIDIETGQPLLGGNGIGYLSGETIKPITLQRIYEIKKQV
                     NIPIIGLGGCVSGDDALEMIMAGADFVGICSVVILKGAQVISKIHDDLKSNLNRLGYN
                     TIENACGIVHNHMGDVNERLSFEFTYDEEKCTKCKMCERVCAYQARKLNDKMELNEEE
                     CRYCGLCISVCKPKALGRKISCSELNV"
     gene            complement(10582..11895)
                     /locus_tag="KR231_002264"
     CDS             complement(10582..11895)
                     /locus_tag="KR231_002264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase family protein"
                     /protein_id="HBH0004631.1"
                     /translation="MIAIKSKYLISSADEIYTNSAVVVENDIIKDILPNEEVEIKYKN
                     IEEIIDKSDAIIMPGFVNGHMHQYGVLSRGIPANVHFTDFEGFLNDYWWPFIENRIGL
                     KEVKATTKASAIELIESGVVAFCDTLEAPNTEEGTLIEQGKILEEIGMKAILSLESCE
                     RISFENGLRCLNENSNLIKWSRENSKLINGIMCTHTSFTCSDRFIKKAKEDTKKLNAP
                     MQFHLCESIYEPNYAEKHFGKKAVDYYNDLDILDETVLASQCVKVNDEEIDILKEKGV
                     KVVHMPLSNCEVGGGFSPVPKMIKKGIKVALGTDGYINDFFEVMRGAFLMHKSVEEDA
                     SVMPANLVFRMATEHGAYVLGLQNSGKIAVGNKADIIVMEDEFKTPVTLDNIFDQIVV
                     QGKKEFISNVYIDGRHILKEKQLVDLDKKAIVKEMKEVACEFWKF"
     gene            complement(11896..14187)
                     /locus_tag="KR231_002265"
     CDS             complement(11896..14187)
                     /locus_tag="KR231_002265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdopterin-dependent oxidoreductase"
                     /protein_id="HBH0004632.1"
                     /translation="MVNKEVRKIDSEAIVTGKPIYTEDLIFHKDVLTIKLLRSPHAFA
                     KIKNIDIKNALKVKGVVNIFTYKDVPNYRYSMVGESYPEASPHDQLILEDVVRYVGDE
                     VAIIAAEDERAAIKAMKLIKVEYEVMTPILDARESEGNKILIHEEDDLFCPFDFGLDA
                     TKNIVSREKMGKGDVEKEFKESDVIVEHSYMTQSQAHCMMETHRAYTYIDTNGRLVVT
                     SANQSAYHMRRQVSKALGIPLSKVRVIKPRIGGGFGGKNIAVTEIYASFVTWMTKRPA
                     KLIYTREETFAMTNTRHQMFFDIKIGSDKEGNIKAIDMKALNNTGAYGDNGPSVCSES
                     GHNVLPTYNNVPAIKFDGRTVYTNLVPGGALRGYGATQGTFALDCAIDELAHKLNMDP
                     TEIKLKNIIKKQTEGGIMNFPIRSCALDECIIRGKKLIGWDEKYPVRDIGNNKVRAVG
                     MSVGTHGSGIANIDMAIVNMRMDEDGTYKLFSGSSDLGTGSDTILAQIAAKALNTSID
                     RISVYTGDTDMCPYDTGAYASCTTYVTGNATIKSAESLKQKILKVAQKKLDLPIDDLI
                     LYEDRVCYSEDVEKFVLLSELGKESVGGGNQEVLYSSESYGIQESAKPFLAGFAEIEL
                     DKTTGEFKVINYACSTDCGTVMNPALARIQVEGGVTQGIGLAMYEDPRHGSDGKLQTS
                     NLLQYKVPTKKDIGNIIVDFVDNYEPTGPYGAKSLGEIVIHTPAPAIANAIYNATGVR
                     IRELPITSEKVYMAMKKLNQGGK"
     gene            complement(14177..14971)
                     /locus_tag="KR231_002266"
     CDS             complement(14177..14971)
                     /locus_tag="KR231_002266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD binding domain-containing protein"
                     /protein_id="HBH0004633.1"
                     /translation="MITIKEYVVPKSLDEAYELLISRKNNIILGGCGFLKLGSKNIGS
                     AIDLKDLALDYINETDDSILIGADTSLRTLELNKVIKNYCNGVISNAVSNIVGVQFRS
                     GARVGASVFAKYGFSDLIPSLLVVDAKVKLYKKGVMNLADFLENELEKDILIEVILPK
                     KDAIGVFDSIRKCTGDFAVLNGAMLKEGSIYKIAIGARPRRAKIAYKASEILSLENDI
                     EKAGEVSSEELSFGSNIRGSKEYRKDMAKALVVRMYNSIGGECDGK"
     gene            complement(15010..15456)
                     /locus_tag="KR231_002267"
     CDS             complement(15010..15456)
                     /locus_tag="KR231_002267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2Fe-2S iron-sulfur cluster binding
                     domain-containing protein"
                     /protein_id="HBH0004634.1"
                     /translation="MIIKCTINNKEKELSIRPDDFLADTLRENGYVSVKKGCDTGSCG
                     LCTVMVNDKAVLSCNYLTARVEGQHITTLEGVLDEAKKFGDFLADEGADQCGFCAPGF
                     IMMVLAMKRELQNPTEEEVIDYVNGNLCRCTGYKGQLRAIHKYLNT"
     gene            complement(15528..16934)
                     /locus_tag="KR231_002268"
     CDS             complement(15528..16934)
                     /locus_tag="KR231_002268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HBH0004635.1"
                     /translation="MMDILIKNAIIVTVNKEREVIFDGALVVKDNKIADIGNSKEIES
                     KYTDVKKIIDAKGKVLFPGFINTHNHLFQTLLKGLGDDMVLKDWLETMTFPAANYLEP
                     KDTYDAAMLGCIEGLRSGITTMVDYMYPHSKPGLCDGIIDAYKELGIRGILGRGCMNT
                     GAQFGVHPGIMQDVETVEKDVRRLFEKHHNTENGRIKIGVAPAAIWSNSQEMLEMLWR
                     VVKEYDDALFTVHISETPFDREAAKELHGQYDIDVLEKLGILGPNVLMVHCVYLTEKD
                     MELTKKYDMKVSHNTASNMYLSSGVAPVPEMLKKGITVSLGVDGAASNNSQDMLELMK
                     LTALQHKVNKCDPLAMSAEKVLELATIDGARAIGMEDEIGSLEIGKKADLLIFNPMLS
                     PKAIPMHNPVSTLVYSSSMKNIESVIVDGNIIMEDSKILTANEEKALKDAQDTAERLC
                     VRGTIKNRMEGHKWNSLY"
     gene            complement(16952..18322)
                     /gene="hydA"
                     /locus_tag="KR231_002269"
     CDS             complement(16952..18322)
                     /gene="hydA"
                     /locus_tag="KR231_002269"
                     /EC_number="3.5.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydropyrimidinase"
                     /protein_id="HBH0004636.1"
                     /translation="MGTILRGGTIITSDKTYISDLRIEDEEIVEIGNNLEINGDKVID
                     ATGKIVIPGGIDTHTHFDMNAGSITTADNFETGTRAAIAGGTTTILDFAEANEGENLL
                     QGVEAYHKKASGNCYCDYGFHMTITCLNKDTFNHMEKLISDGIVSFKMYMAYDGMKVD
                     DGTIYRVLKKARDLGCIVGFHCENGDLLDVLIEENIQNGNLEPKYHPLTRPNIVEKES
                     VSRLADITKLSNSKSYVVHLSCRESLETVKMAREKNIDMIVETCPQYLLLEDNLYNKD
                     KFEGAKYVMSPPLRKKEDINYLWEGLSSGDIQTVGTDHCSFNFKGQKDLGIDDFSKIP
                     NGAPGVEHRLALLYTYGVLENRISANKFVEVTSTNAAKIFGMYPKKGEIAVGSDADIV
                     ILNINKEETISYKTQKQNVDYTPYEGFKVKCKVEDVFLRGNHVVQSCNVKEHPTGQYI
                     KRKITK"
     gene            complement(18455..19642)
                     /locus_tag="KR231_002270"
     CDS             complement(18455..19642)
                     /locus_tag="KR231_002270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YgeY family selenium metabolism-linked
                     hydrolase"
                     /protein_id="HBH0004637.1"
                     /translation="MLNEQRKQEVTEICQKLIQNPSSSGNEEGVVKAIEESFEKLGFD
                     SWSRDRYGNIVGCIKGNKPGKKILFDGHIDTVPVPDASKWSVPPFEGKIVDGKIYGRG
                     TSDMKGQYTAMMSAVAYFAKDTNRDFAGELYVAGVVHEEIFEGVSAREISKAVQPDYV
                     VIGESSELNLKIGQRGRGEIVVETFGKPAHSANPEKGVNAVYKMANVIQKIQQLVPPT
                     HPVLGDGILVLTDIKSSPYPGASVVPDYCKATFDRRLLVGETREGVLAPIQALLDEMM
                     KEDPELNAKVSYAVEKADCYTGNTIESERFFPGWLYDEEDEFVQAAYKGLKEAGIDSE
                     ITQYSFCTNGSHYAGEAGIKTIGFGPSKENLAHTIDEYIEQEQLFIGTEGYYGILKSV
                     YGK"
     gene            complement(19769..20983)
                     /gene="dpaL"
                     /locus_tag="KR231_002271"
     CDS             complement(19769..20983)
                     /gene="dpaL"
                     /locus_tag="KR231_002271"
                     /EC_number="4.3.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopropionate ammonia-lyase"
                     /protein_id="HBH0004638.1"
                     /translation="MLKEIKWKVNNLPKGDKENCIKFLNEEEITKVRNFHKSFPQYKE
                     TPLANLEGLAKKLGVAGVYVKDESYRFGLNAFKVLGGSYSMGRYLAQRLDTDISELGY
                     DKLTSKEIKEKLGEITFFTATDGNHGRGVAWTANKLGQKSVVLMPKGSSEFRLNKIKG
                     EGADASITDLNYDDAVRLANDYAEADDHGVMVQDTAWDGYEEIPAWIMQGYGTMAQEA
                     IEQLKEYGVDRPTHVFVQAGVGSLAGAVQGYVASIYDECPITVVVEADEADCYYKSAE
                     AGDGKPRFVGGDMPTIMAGLACGEPNTIGFEVLKNHAAAFVSAPDWVSAKGMRTLGNP
                     LNGDEKVISGESGAVTTGLLVAAMEREDLADLRKDLKLDENSRILLISTEGDTDPDKY
                     RSIVWDGEYPSI"
     gene            complement(21346..22017)
                     /locus_tag="KR231_002272"
     CDS             complement(21346..22017)
                     /locus_tag="KR231_002272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin family protein"
                     /protein_id="HBH0004639.1"
                     /translation="MAKILGICGSPRKGATEYAVLEALKEAETIPGIETEYWSVRGKK
                     ISPCVHCDACIRKETMCIIKDDIQELEQKILEADGIIVGSPVYDMNITAQLTAVFNRL
                     RPMYLVHPGKLQNKVGAAITTGGTRYGGQELTKLPIINFFLMHEMLVSGGLGGCYIGG
                     TIWSKDGKAKGAQEDETGMDTVKRLGKGAAEAVMVSKFGLEKWNVVKEELDVKKDEKS
                     PLRDH"
     gene            complement(22100..24316)
                     /locus_tag="KR231_002273"
     CDS             complement(22100..24316)
                     /locus_tag="KR231_002273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdopterin-dependent oxidoreductase"
                     /protein_id="HBH0004640.1"
                     /translation="MEKVIGKSYPLKDAALKVTGQMKYVADMKPQNVLYAKMLLSPVA
                     HAKIKSIDTSEAEKVVGVRAIATYLNTSQRKYNGSLRFYEHKIPENEVIFSDTVRFVG
                     DRVAAVAAETPEIAEKAVKLIKVEYEELPAVFTIQDAIKEDAICIHGDSNIVSQNNIN
                     GGDVEKGFKECDYIFEDEYSTPAIHHSAIETHSVIAHYDYNDKLTVHTPCQNTFGFRI
                     ILSQIFGMSLNKVRVIRPAIGGSFGGKLELTIEPVAAALSKMTRRPVKMVLTRKESMI
                     STRTRHGSFVKLKTGVNKDGEVIAQDIKIYTNTGAYASSALNVIGALSHKVFKVYKIP
                     NIKFTGMPVYTNTPIAGAMRGYGSPQIFMAQQAQFAKIAKEIGMDLVDFQNKNAVEPD
                     DVDIIFHGSLGNPRVLDCIEQGKKMFKWDEKKKLPKEEGKYLRGIGMAIGAHGNGVFG
                     AHRDVVTLTLKLNEDGTLTLLTGAHDMGNGVVTMQTMMVAEVLGITPDKVDTFETDTD
                     ACTFNLGDYASRGVFVEGGGAKKTAEKLKNLILEEAEKLLETSKEDLYLDNGCVISKL
                     DENVKASLSDVAVYSQSKSLRELTVVEDYSSPAGRTSYGVHFAEVLVDKETKDIKVVD
                     FVAVHDVGRVINPLNLEGQLEGGIHMGLGYALSEELAFDEQGRPKATDFKTYKLFRTV
                     DMPKCQVAFVDGYEKAGPFGGKSIGECAVVPVAPAVANAVYNATDVEIHSLPIKLK"
     gene            complement(24319..24789)
                     /locus_tag="KR231_002274"
     CDS             complement(24319..24789)
                     /locus_tag="KR231_002274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="(2Fe-2S)-binding protein"
                     /protein_id="HBH0004641.1"
                     /translation="MEKIKLNINDYMYEIEVEKNETLLHVLREKLNLTGAKQGCNSGS
                     CGACKVLIDGVDMKSCKLLAKNCEGKVIYTIESFANGENLHPIQEAFIEVGAVQCGYC
                     TPGMIITTQALLNRNASPNEDEIREAFKENLCRCTGYVKIIEAVKLSAARLGGR"
     gene            complement(24851..26245)
                     /locus_tag="KR231_002275"
     CDS             complement(24851..26245)
                     /locus_tag="KR231_002275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HBH0004642.1"
                     /translation="MIDILIKNAIIVTVNKDRDVIFDGAIAIQGDRILDIGNTVDIEP
                     KYLDAKKVIDANGKVIFPGFINTHNHLFQVLLKGLGDDMALHEWLNTMMFPSAKFLTE
                     QDTYDAAMLGCMEGLKSGITTMVDYMHTHNRPGLTDGIVKAYKDLGIRGVVGRGCIDL
                     GIHKELIEDVETVEKDLRRVFEKYHNSENGRIKICVAPSSMWAISEEMGKMLWNIVKE
                     YDSYFTVHISETEFARTATKDIHGEIDIKLLEKWGIVGPEVVAVHCVCITDEDMEMLK
                     KYDIKVSHNVASNMYLASGVAPVPEMLKKGINVSLGLDGAASNNAQDMVELMKLTALQ
                     HKVNNCDPLAISAEKVLEMATIEGARTLRMEDEIGSLEIGKKADLVIFNSMLSPKSIP
                     LHNPVSTLVYSASMHNVESVLVDGNVILENGKVTTIESEEQVLLNAQHAAEELCKRAN
                     VTNRMEGHKWNSLY"
     gene            complement(26318..27679)
                     /locus_tag="KR231_002276"
     CDS             complement(26318..27679)
                     /locus_tag="KR231_002276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine/pyrimidine permease"
                     /protein_id="HBH0004643.1"
                     /translation="MKTRNTSKYDVDGIPPLKESIPLALQHLLAMIVGNMVPAILIAN
                     VVGLNQGQATMLIQGSMLAAGLATFLQLYPIPLFKGFKLGSRLPVMMGMSYVFLGACL
                     SVAAKDGLAALFGAQIAAGVIVFFVGFGVKKIRHIFTPIVSGTIIACMGLGLFATAIK
                     NLAGGEGTQTFGSPINFTVGVIVAFVIIMINKYGKGLVKNSSILIGILVGYAISLVLG
                     LVDFSAVQGAAIVSLPTPAAFGLEFRPELIVMFTIIYIIGIADMMGACTIATVGAMDR
                     EVTDEELASVVLGNSITSIISSLFAALPTGVFSQNTAIVSMNKVTSRFVIALGALVLL
                     LAGISPALGAIMTTIPSCVVGGATLVVFSSIAMSGFSIMSMDGFTEENNLIAGVSIAT
                     SMGLTTAPQVLDQFPETIGTVLGGSSIVSGAIIAILLQTLFKLKSRKSAENVTSNLEE
                     NIG"
     gene            complement(27976..29298)
                     /locus_tag="KR231_002277"
     CDS             complement(27976..29298)
                     /locus_tag="KR231_002277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine permease"
                     /protein_id="HBH0004644.1"
                     /translation="MFDIDGRPPILKCLPLSMQHILAMIVGTVTVPIVVGGAVGVSPT
                     QITLLVQYALIIAGISTLIQLYPIGNIGSRLPIIFGVGFTYVPTLVAVGGNYGLASIL
                     GAQLIGGVATVLIGIFIKKIRKFFPNIVAGTVVFTIGLSLYPIAINYMAGGVNSPTYA
                     SMQNWAVAAITLVVVIGLSQFAKGYAKLAAIFLGIIVGYCVSLVLGIINFDPIREATW
                     FAIPKPLEFGMEFDMPVIISVVIVSIINAVQAIGDLSATTMGGMDRNITDKELSSGVI
                     GSGICTMIGALFGGLPPSSYSQNVGMVAMNKVISRFVLGIAGIFMLLSGFVPKFGALM
                     TTIPYSVLGGATISIFSIITMTGIKLIITEELSSRNITIVGLAIALGMGITSVPAAQE
                     AFPSFVKLVFGESPIVIATLVAFVLNLIIPNKSLEDEAKERAVMEETN"
     gene            complement(29654..30694)
                     /locus_tag="KR231_002278"
     CDS             complement(29654..30694)
                     /locus_tag="KR231_002278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HBH0004645.1"
                     /translation="MDKHSDSVMYGGMEVYNIWGTTTVDSIIGESDVMRALKNRICKI
                     GNSDSTVAITGESGTGKELIARAIHLAGNRGNKTFVAINCAAIPEPLLESELFGYTKG
                     AFSGADSKGKIGKFELANGGVVFLDEIGDMPIQLQSKLLRVLQEKKFTRIGSNELIDI
                     DVRIISATNRDLFELVKENKFREDLYYRLNVIPLEVPPLRERGDDIQILINNFIDKYS
                     RKMKKNVYHIEPDVEQMLLKYPWPGNIRELENTIELALNLLEEDGIIHKGIINRKILE
                     YFKLNNINIKLLEESDYEISMEQDILTLEEFERAYIKKVLKFYGNDTKSKKLAAKKLG
                     ISLATLYRKIDV"
     gene            complement(31021..>31966)
                     /locus_tag="KR231_002279"
     CDS             complement(31021..>31966)
                     /locus_tag="KR231_002279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="McrC family protein"
                     /protein_id="HBH0004646.1"
                     /translation="LSLKNYNLLNFFVMYFIESMQTQMKKGIYFEYINKIENLNVMRG
                     KILLSTYAKEKGISPMKIRCEYDEYSENNFLNQVLKKACISILCRINDNSIQGKIKKI
                     LSYFQNVDLIYIDRKKLLDYKFYKNNDRFKDCYLLARLILLNLSMDNSQNNQEAFSIL
                     FEINTLYEEYIGILIKSIWDNSFRETYIQDKSKFLLKNEQTGKKNFNLRPDIVLYDLK
                     NEYEIIIDTKWKAIEVDSNVFYRSSDIYQMYAYITAYENAKRCILLYPCIQKDKNYSS
                     WKLSESFKGKFIEAKTVRLDDIKNTKNDLKKIIFNYKF"
BASE COUNT         9695 a         6248 c         3461 g        12562 t
ORIGIN      
        1 tatcttacac aaaatttttg ttttacactt ccataaaata tctctatttc actttcatat
       61 tctttaatat tttctactaa ttttatagct aaatttttat atttttcatt ttcaacttta
      121 ttaataaata atactctttt tccagaataa tttttaaata atccatttgg atttaatact
      181 atatttttta agttttcaat acttactgta gaactactat taatactact tgtatctaaa
      241 tttgctattt ttttaaatat ttctactcta tgtatattct cttcattaat attcattcca
      301 aatgatgtta tatctaatat ccctatggtt tttgtagttt tatgatatac tactggttct
      361 ttagcattcc aacctttaag tttttttctc tttgagccat ctccctctat taaaactaaa
      421 tcaaattggt ctacaatttc atccaaaata gaggaatcaa tacttactaa tttattttca
      481 ttatttatat aactgccaca gactgttatt ccatgacaaa tagatggaat aacagttcca
      541 tctattgtaa taattatatt gtcataatcg tttggtacat atattttagt tgttgttgta
      601 aggagaactt tcaatttatc tctataaaaa tttgcaaaat agtttataaa cgaagttttt
      661 cctcctgctc caactacagt tattatttca ttcttttcta ttatatttga tagttccaca
      721 ctttcacctc ttataaccag ttttctaatc tcttaattat tatagttaga cctttttagt
      781 aaaagtgatt tttgaaattc cataaactcg aaagtaaata gattctgttg taaacaacaa
      841 ggcggatcca attcgccgct aagctgtaag cttacgctat cagtttatct tttaaatata
      901 attaagatat tcttactctc tgtggttgct ttaatatttg aggattattc tgtaaattag
      961 ataaattaac tacttgtgat ttttttagta tattaagact cgcatttaca tctgcattta
     1021 taatgattcc aacactggat ttgtactgtc cacgcgttat tctttcccct ttaaagtcat
     1081 attttttaac attgtccaca ttgatatcag gtagaaaatc atcagcaaaa aaatctgatt
     1141 tactagtata gctttcttct tgcctaataa aattgatatt ttttatttta cacagatatt
     1201 ctaattttcc ttttatctct ccaaatggga ttcttataaa atttctatat atttttctct
     1261 ccatattatc acttttttct aacttagcat tatatcctac aattaaattt ccaatattat
     1321 tttttacaca ataatcaatt atataaaaac aggttttatt tacatagtct ttaacttgat
     1381 tatttctctt attccaaact ttaaattgtt ttcttgttat tgcagttata ttctttttta
     1441 attttaaggc ttctatttta tcattctgtt tgtttgccca ctgattcaca gattttagcc
     1501 tttttccatc tatgataaaa ctatcaccta aattggtaac acatgtacat aaattttcta
     1561 aacccaagtc tatagctagt gcattttttt gatttgaaac ttcctctgat tttggtattt
     1621 cataacaata ctgaatttca aagaacctag ctttatgttt aggtattatt cttatttctt
     1681 taattttttt ctctagtata ttttgtggaa cttttatact tactttccca tatagttttt
     1741 taaatgctgg agacataggt acatttaaaa tcccatcttc tttgattctt atttgaccta
     1801 ttattatgct aaaaaatcct tctttatcta aatatttagg tgattttatc cctctaaagt
     1861 catattttcc ttctttggct aatttaatta atccaaaaaa tgacctaaac gaactgtcta
     1921 cttcttttaa tatttgttgc gctatattac tattgagaag cttatagttc tcattttctt
     1981 tgcatacatg ataattagct tcatagttaa gatgttctcc ttgattgaaa taatgctgtc
     2041 ttacattata tgtaccaaca ttatataagt tcttagctaa gaagcacatc tctcgtagag
     2101 cttgatattc ttttttagtt aagtttttta attgttgtct ctgagttcca tagtgtatat
     2161 tttttattct gtttgacatg aactcacctc ctttagaata tactctacta gacattatat
     2221 acggtatttt tacaaaacac catatataat gtccatttaa ttactttatt ttacaaaata
     2281 atttaaattt acttgctttt atacacatta ttatttatta taattgttta ttattatttt
     2341 tcatacccat ataaactttt tcaaaagtca taggaagctc tcttaaacga actcctgtag
     2401 cattaaatat tgcatttgct atagctggtg ctggtgtatg tataactatt tctcctaatg
     2461 atttagcacc ataaggacct cctgggtcga aattctcagc aaaatctacc aatatatttc
     2521 caacttcttt ttttgtagga actttatact gtaggaaact atctgttaat aatctaccat
     2581 ctttatcaaa tatagggtct tcatacattg caaaccctat acccatcatc acaccacctt
     2641 ctacttgtat tctagctaaa gttggattta taactgttcc acaatcaggt acacatgcaa
     2701 aatttatgac tttatattcg cctgtatttt tatctaattc tatctctgca aatcctgcta
     2761 taaatggttt tatttttttc aacatgccaa aagattctgt tgcttccaaa actactggta
     2821 catcatcact agcaaatcct attcctccaa cagattctct acccaattcc tctaatagaa
     2881 caaacttgct attatcgttt ttaacaaaaa ccctgtcttt tcccaactct aaatcttctt
     2941 ttttaaatcc tagctttgac tctgcaactg aaagtaatat atcttttaat ttatttgctg
     3001 tctttattgt tgcatttcct gtaaccgttg tcgtacaaga agcaaatgct cctgtatcat
     3061 agggacataa gtctgaatca cctgtataaa tagaaattct atctacagta gtatttaaag
     3121 cttccgcagc aatttgagct tgaattgtat cagccccttg acctaagtca gcaagaccag
     3181 ataatagttt atatgtgcca tcttcatcca ttcttatagt gactgttgcc atatctacac
     3241 gcggtatacc agaaccatga tttgctactg ccatacctac tgctcttact ttgttgtttc
     3301 ctatatcttt acatggatat ttatcatccc aattaattaa tttcttgccc ttttctatac
     3361 attgtctcag ctcacaactt aatatttcgt cttcagctgc ttttccattg gtatacctat
     3421 ctattatatt tttaattcta aattcaagtg gatccattcc aatcttatgt gccaattcat
     3481 caatagcact atctattgca aatattccct gtgtagcacc ataccctcta agtgctcctg
     3541 ctggtaacct attagtatat actgttctag cattaaatct aacagcatca atatcattat
     3601 atattggtaa ggtattgtgt ccagattcgg aagaaacaga gacaccattc ccaccataag
     3661 cacctgtatt gtttaatgac tttagctcta ttgcttttaa atttccttct ttatctgcac
     3721 caactttaac atcaaaaaac atttcatgtc tactattaga acctacaaaa gtttcacttc
     3781 ttgtaaatac aaattttgct ggtctaccag ttttcatagt aacaaatgca gtaaatatat
     3841 ctgttgctgc tatattcttt cctccaaatc caccacctat tctaggttta attactctta
     3901 tttttgaaga tggtataccc aatacttttc taagtattct ctttacattg tgtggtgatt
     3961 gtaatgatga aactacaaca attctatcat ttatatcttt atatgaatat gacctatgag
     4021 tttccatcat gcaatgcgat tgactttggg ttttgtatga agattcaacc acaaaatcac
     4081 tttctttaag cttagcttca acatctccaa attcaaaaaa ttcttttgat actatattat
     4141 tttttgcatc caatccaaaa ggatatggct ctactatgtc tttttctgga tgtataacaa
     4201 cttcatttcc ttctgcttct cttgcatcaa acacaggctt taaaacctca taatctacct
     4261 ttatcatttt taaggcttta agtgccgttt tctcatcttc agcagccact aaagctactt
     4321 catctccaat aaatctaact gtatcttcaa gtaaaactct atcataaggt gatgcttctg
     4381 gttctgtttg acctggcaca caatatctga cctgtggtac atctttatac gtataaatac
     4441 ccacaacccc tggaattttt tcggcttttg atgtatctat attctttatc ttagcatgag
     4501 catgtggact tctaagtagt tttaatgtca aaacatcttt atgcataatg aggtcttcag
     4561 tatatagagg ttttcctgtg acaattgctg tactatctat ctttcttatc cccttattaa
     4621 tcattataca ttccctcctc aatagcatta tacatccttt taactaatgc acttgccata
     4681 tcctttctgt actctttact agctctcata ttacttccat aagtaagttc cttactagca
     4741 acaatagatg ccttatctat atctttttct ttatttaata tattactcgc ttcaagtgct
     4801 aatctagctt tttgaggtct tgccccaatt gctattttgt aagtatcatt ttcttttagc
     4861 attgctgaat ttaatacaga aaaatctcct gtgcattttc ttattgagtc aaaaacagct
     4921 attgcatctt tttttggtag tattacttcg accaatatat ccctacttaa ttcactatcc
     4981 aaaaactcac ttaactctag tattccttta ttgtataatc tcaccttcgc tccaacaacc
     5041 aaaagcgctg gtattaagtc agaaaagcca tactttgaaa atacacttgc accaattcta
     5101 gccccttgtc taaattgaac accaactata ttagaaacag cgcttgaaag tattccacta
     5161 cagtaatttt ttatagtttt atcaatttct aaacttctaa gtgaagtatc tgcacctatc
     5221 aaaatatttt ttttatcctc ttttatataa tttagattta tatcttttaa atctatcgct
     5281 gttcctatat ttttattact taattttata aatccacatc cacctaaaat aacattattt
     5341 tttttagaaa ttaaaatttt atatgcttct tctaaactct gtggaactga atattccttt
     5401 atagtaacca tcttatcccc ccatcattaa cttattaaaa cacaaaagtt tttaataaat
     5461 cttttattta tatttataat tgtagtatat ttaattcaca tatattaaac ctttacatta
     5521 taaactttta tttttatcct caaccttatc acttttattt ccaggaaatt ttaccatata
     5581 taaagcttga attattatgg ctaccattgc tcctgaaact acacttgaat ctgcaagtaa
     5641 tgtctctata aattttggaa atttttcaag aacttgagga gctaccatga atccaatacc
     5701 agaagccata gaaagaccta atatcatgct attttcttga ttaaatccat ccatactaac
     5761 aagtcttaaa ccagatgttg taagagttga aaatataacg agtgttgctc ctccaaccac
     5821 acagggagga attgttctta ttaaattagc taataaaggc gatattcctg ccaaaaataa
     5881 tccaattcct ccaatagcta gtacaaattt acttacaacc tttgtattgg aaacgattgc
     5941 agaattttgt ccaaacatcc ccattggagt tgcagaaaat aatgcaccta ttgtagagag
     6001 tactccattt cctaaaacag cagaagaaag ttcttcatct gttacttgtc tattaagccc
     6061 tcctaccgca gaaagtgtac aagcacccat tatatcagct atctcaacta aatatattat
     6121 tgaaaacatt acaacaactt caagtcttat atctagccca aaagcaagtg gttttggaag
     6181 tgcaaccaaa gtaaactcct gaattgaaga aaaatttact atacccaaaa ttaatgataa
     6241 aatgtatcca aaaattatgc taactaatat tgatgcatct ttaaataatc cttttccata
     6301 cttatttaat cctaatatca taagagatac agatattcca actataaaat taattggatt
     6361 cccaaaagtc tcattgccca tacccccagc taagtttttt atagctattg gaaaaagtcc
     6421 aagacccata catgcaacta ttgttcctga tacagctgga gtaaatataa atcgtatttt
     6481 tttaagacca aaaccaatta taattattac tataccagct attatttgag agccaaataa
     6541 tactggtagt ccatacttac ttgcaacaga taccccagct cctataaaca tagctgtagc
     6601 tcccattata actggtattc ctcctcctaa tttaaaacct ttaaacaaag gtattggata
     6661 taattgtaat aaagttgata atcctgcaaa aactaatgcg gcttgaatca ataatgttga
     6721 catcttatga ttaagtccag ctgcatttgc aatcaatatc gctggtaaac aactacctat
     6781 taccattgcc attaagtgtt gtaaccctaa aggtattgct tcctttagtg gtggtattcc
     6841 gtctaattca aattttgatg tactttttgc tttcataata aaaactcccg ttacataaaa
     6901 cttattgaat tatataaata cttaaaaatc taatatatta aattaatgat gttcataaat
     6961 atcaactata ctccaacata tatttaagtt tttagtctta aaaaacagat gcaataaatt
     7021 taattattaa caaataaacg tattctttaa ttttgtatac attatatacc atgctttaca
     7081 aatataagag tattatagct atgaattttt aattttttat agtaaattta attcaattta
     7141 aatctttcaa tcttaatcat tataagttat aagttttcat aagtatttac atgtttcaag
     7201 ttttaaacat ttacctataa acgctacttt atagatgtca cttcaaatcc agtgacctca
     7261 tactttcata tgagcgtaga ctatttcttc atcttcagca ttacctgcta agagcaaccc
     7321 gtttccacta tcaatcgctt atagtgtact ctctctcgag atagtcgttt gaccttccta
     7381 tttctaggct tggcgaccaa atgtccattt ttaagtactt aggctctcac catataccat
     7441 cctcactatt gtttctggtt ttcaccacat tcataaaagt ttctttctat cttttattgt
     7501 agttgcaagg ctttaggatt tactggtttt aaagttgtgt cctacataga tttctctatg
     7561 tacggggcca aaagtacaat ttatttaaca tactttgctt taccccctgt aaataatatt
     7621 atttactctt tcactgtttt tgttattaaa ttaattaaat atcaattaat ctaagcataa
     7681 aataattatt taatttaaac tcaaaatatt tatgaatatt ttataatata attctcataa
     7741 gacagaaaaa cttaataagc tatgtatctc agttgtacca atgtactctc ctttactata
     7801 tttgtatctg caacataaaa tatacaagtt tctatctatt tatagatata tatatctata
     7861 agcaaaatag taatattatt tttaatagta aaaattttat tcatattact atttataatt
     7921 tttatagagc aattttagtg ccaatatttg catacatttg tatagtataa aatttttatg
     7981 ttctcattga taaaatttta cttatttcaa gcgttctatt agattttatc atctaaattt
     8041 taggttttat ttttataaat taattgtatt tacataaaaa aaaagaccta aaaacaaatt
     8101 tttaacggtc ttttctcaat tttttatttt catttctaaa atttataata aatagtaaga
     8161 acactataaa ttcttttata taaaattctt agtttgtgga tgataaatta gtgaattaaa
     8221 atactacttt actgatttta gtttgacaat atcactccaa tttttactag tggctaactc
     8281 tactaaattt aagtctcttc ttatttcagc tatatcctct tttatagaat tagtgtcacc
     8341 ttttatatat gctatgttat gttctatatt atcatgagta gctttattta tttcagaatt
     8401 atgtaataaa cttcctaaaa tattattctg ttctatctgt atctctttca ttgatttatc
     8461 ttcacattct agactatcaa tcttaatttc aattccatat aatttttcat ttgctatgga
     8521 tacctcgtcc ttaattccat tcatatcttc attaatgtta tttattttat tttgcataaa
     8581 gtttacttct gatttaactt cggaaacatc ttctttcatt acagttattt cttgtctcac
     8641 ttctgacatg tcttttttca ttacatttat ctcttgtttt acctctgatg tatcttcttt
     8701 cattacagtc atttcttgtc ttacttcgga catatcttct ttcattacag tcatttcttg
     8761 tcttacttcc gacatatcct ctttcattgt atttatctct tgtcttacct cagacatatc
     8821 ctctttcatt atatttatct cttgtcttac ctcggacata tcttctttca ttacagtcat
     8881 ttcctgtttt acttcggaca tatctacttt taatacattt atttcctgtt ttacttcgga
     8941 catatcttct ttcattacag ttatttcttg ttttacttcc gacatatctt ctttcattac
     9001 agtcatttct tgttttactt ccgacatatc tccttttaat acatttattt cctgttttac
     9061 ttccgacata tcttctttca ttacagtcat ttcttgtttt acttccgaca tatcttcttt
     9121 taacacattt atttcttgtt ttacttccga catatcattt tttatgctaa ctacatcttc
     9181 atttatagta tataataact ctaaaatctt ctcttgcact tgcatcacca tccctattaa
     9241 ttattataac attttacaca aatgctatac aatgttaaca tatatatcag aattattaaa
     9301 attttaatta aacaaaattg attcacttta ttacttcaaa actaattaat atctaaaata
     9361 actacaaata aacaaaaata aggtcaacaa caaaaaaggc ttatctcttt gagatagcct
     9421 ttcttatttt tatttaaaac tttgtttttt ataaaataat ctatacattc agctctgaac
     9481 atgaaatttt tcttccaagt gcttttggtt tacaaactga tatacaaagt ccacaatatc
     9541 tacactcttc ttcattcaat tccatcttat cattcaattt tctcgcttga tatgcacaaa
     9601 ctctctcgca catcttacat ttagtacatt tttcttcatc ataagtaaac tcaaagctaa
     9661 gtctttcatt aacatctccc atatgattat gtactatacc acaagcattt tctatagtat
     9721 tatatcctaa tctattaaga ttagatttta aatcatcatg tattttagat attacttgtg
     9781 cgccttttaa aattactact gaacatatac caacaaagtc agcacctgcc ataatcattt
     9841 ctaaggcatc atctccactt acacatccac ctaagccaat tattggtata ttaacttgtt
     9901 tttttatttc atatattctc tgtaaagtta ttggcttgat agtttctcca cttaaatatc
     9961 ctattccatt tccacctaat aaaggttgcc ctgtttctat gtctattcta aatgctggtc
    10021 ctacagaatc acaagcagtt attgcatctg ctcctgcttc ttctaatttt ttagcaaaat
    10081 cgcctatctc atctatcata ggaggaagtt taactattac aggtatattt actctttcct
    10141 ttgcatcttt aagcattggt atcaaatctc tatagtcata agatactaat tcaataaagt
    10201 cagctcctgc atttgcaact ttctctacta attcgctact ttcttcaatt gtatgaccta
    10261 ctgaagctat acagacagtc ccatctcttt tcatttgtgg tatttcaaaa tctatccatt
    10321 gctctggctc aaaatctgtc catttttcat tatttaaaag agcattagct gtatttctaa
    10381 ccatatgtgg tgctggattt atagctcttt cttttcttat agtcttagtc acaactgccc
    10441 ctgctcctgc atcacttaat atcttgcatc cagctgcact atatgttaat ggtcctgaac
    10501 ctattataag tggtgatttt aattctttac ctaaaaaatt atacattatc tgcttcccct
    10561 tttcatatat atttacattc gttaaaattt ccaaaattca caagcaactt ctttcatttc
    10621 tttaacaata gcttttttat ctaaatcaac taactgtttt tcttttaaaa tatgtctacc
    10681 atctatgtat acatttgata taaattcttt tttaccctga actactatct ggtcaaatat
    10741 attatcaaga gtcacaggag ttttaaattc atcttccata actattatat cagccttatt
    10801 accaactgct attttaccag aattttgaag tcctaataca taagcaccat gctctgttgc
    10861 cattctaaat actaaatttg ctggcattac tgatgcatct tcttcaactg atttatgcat
    10921 taaaaatgca cctctcataa cttcaaaaaa atcatttata tatccgtcag tacccagtgc
    10981 cacttttata ccttttttaa tcatttttgg tactggagaa aaacctccac ctacttcaca
    11041 gttgctaaga ggcatatgaa ccacttttac acctttttct tttaatatat ctatttcttc
    11101 atcatttact tttacacact gagatgctaa tacagtttca tccaatatat ctaaatcatt
    11161 atagtagtca actgcttttt tgccaaaatg tttttcagca tagtttggct catatatact
    11221 ctcacataaa tgaaattgca ttggtgcatt taattttttt gtatcttctt tagctttctt
    11281 aataaatcta tcagaacatg tgaagcttgt atgtgtacac attattccat ttattaattt
    11341 actattttct ctactccact ttattaaatt agaattttca tttaaacatc taagtccatt
    11401 ttcaaagctt attctttcac aactttctaa ggataaaatc gctttcatgc ctatttcttc
    11461 tagtattttt ccttgctcaa ttaaagttcc ttcttctgta tttggagctt ctagggtatc
    11521 acaaaaagct accacaccag attctataag ttctattgct gatgctttag ttgttgcctt
    11581 cacttctttc aatccaattc tattttctat aaatggccac caatagtcat ttaagaaacc
    11641 ttcaaagtcg gtaaaatgta catttgccgg tattccccta gaaagaactc catattgatg
    11701 catatgacca ttgacgaatc ctggcattat tatagcatct gatttatcta ttatttcttc
    11761 aatattttta tattttattt caacttcttc atttggcaat atatctttta taatgtcatt
    11821 ttctactaca acagcagaat ttgtatatat ttcatcagca gaagatatta agtatttact
    11881 tttaatagca atcatttatt tacctccctg atttaatttt ttcatggcca tataaacttt
    11941 ctcagaagtt ataggaagtt ctcttatacg aactcctgtg gcattgtata ttgcatttgc
    12001 tattgctggt gcaggtgtat gaataactat ctctcctaaa gatttagctc catatggacc
    12061 tgttggctca taattatcta caaaatcaac aattatgttt cctatatctt tttttgttgg
    12121 aactttgtat tgtaatagat tagaagtttg aagctttcca tcagaaccat gtctagggtc
    12181 ttcatacatt gcaagcccta taccttgagt tacaccacct tcaacttgta ttctagcaag
    12241 tgcaggattc ataactgtac cacaatctgt agaacaagca taatttatta ctttaaactc
    12301 ccctgttgtt ttatctaact ctatttcagc aaatcctgct aagaatggtt tagcactctc
    12361 ttgtatacca taagattcag atgaatataa aacttcttga tttccaccac caacagattc
    12421 ttttcctaat tcacttaaca aaacaaactt ctctacatct tcactataac aaactctgtc
    12481 ttcatatagt attaaatcat ctattggtaa atcgagtttc ttctgtgcta cttttaatat
    12541 cttttgtttt aaactttcag cagattttat tgtagcattt ccagttacat aagtagtaca
    12601 agaagcgtat gcaccagtat catatggaca catatctgta tctcctgtat aaacggaaat
    12661 tctatcaata gatgtattca atgcttttgc agctatttgt gcaagtattg tgtcagaacc
    12721 agttcctaag tctgaagacc cagaaaacaa cttataagtt ccatcttcat ccatcctcat
    12781 atttactatt gccatgtcta tgttggctat accagaacca tgagttccca cagacattcc
    12841 aacagccctc accttattgt ttccaatatc cctaacaggg tacttttcat cccatccaat
    12901 aagtttttta cctctaatta tacattcatc aagtgcacaa cttcttattg gaaaattcat
    12961 tattccgcct tcagtttgtt tttttataat attctttaac tttatttctg ttgggtccat
    13021 attaagttta tgcgctaatt catcaattgc acaatcaagt gcaaatgtac cttgtgttgc
    13081 tccatatcct cttaatgctc ctcctggaac taaattagta tatacagttc tcccatcaaa
    13141 ttttattgca ggtacattat tatatgttgg aagtacatta tgacctgatt cagagcaaac
    13201 tgaaggtcca ttatcgccat aagcgcctgt attgttcaat gctttcatat ctatagcttt
    13261 tatgtttcct tctttatctg acccaatttt tatatcaaaa aacatctgat gtctagtatt
    13321 agtcattgca aaagtttctt ctctagtata aattagtttt gctggtcttt ttgtcatcca
    13381 agttacaaat gatgcatata tctctgttac agctatgttt tttccaccaa aacctccacc
    13441 tattcttggt tttattactc tcacttttga aagaggtatt cccagtgctt tagaaacctg
    13501 tcttctcata tgataagctg attggtttgc agaagttact actaatctgc cattcgtatc
    13561 tatatacgta taagctctat gagtttccat catacaatgg gcttgtgatt gagtcatata
    13621 agaatgttct actattacat cactttcttt aaactctttt tctacatccc ctttacccat
    13681 tttttctctc gatacaatat tttttgtagc atccaatcca aaatcaaatg gacaaaacaa
    13741 atcatcttct tcatggatta aaattttatt tccttccgat tctcttgcat ccaatatagg
    13801 agtcattact tcatattcaa cttttataag tttcatagct ttaatagcag ccctttcatc
    13861 ttcagcggct attatagcaa cttcatctcc tacatatcta actacgtctt caagtattaa
    13921 ttggtcatga ggtgatgctt ctggatatga ctctccaacc attgaatatc tataatttgg
    13981 aacatctttg taagtgaata tgtttactac accttttacc tttaatgcat tttttatatc
    14041 tatgtttttt atcttcgcaa aagcatgtgg acttctaaga agcttaattg ttaaaacatc
    14101 tttatgaaaa attaaatctt ctgtatatat tggttttcca gtaacaatgg cttcactatc
    14161 tatttttctt acctctttat ttaccatcac actcacctcc aatactatta tacattctca
    14221 ctactaaggc ttttgccata tcttttctgt attctttact tcctcttata ttacttccaa
    14281 atgaaagttc ttcacttgat acttcaccag ctttttctat atcattttct aaacttaata
    14341 tttcacttgc tttataggca atttttgctc ttcttggtct agcgcctatc gcaattttat
    14401 aaatacttcc ttcttttaac attgctccat ttaatactgc aaaatcacct gtacattttc
    14461 ttatagaatc aaatacacct atagcatctt ttttaggtaa tataacttct attaatatat
    14521 ctttttcaag ctcattttct aaaaaatcag ctaagttcat aacccctttt ttatataact
    14581 taacctttgc atctaccact agtaatgaag gtattaaatc tgaaaatcca tacttagcaa
    14641 atacgctagc tcctactcta gctccacttc taaattgaac tcctactata ttagaaacag
    14701 cgtttgaaat taccccatta cagtaatttt taataacctt atttaattct aaagttctta
    14761 aacttgtatc tgctccaatt aatatgctat catcagtttc atttatataa tctaaagcta
    14821 agtcttttaa atctattgct gaaccaatat ttttactacc tagttttaaa aatccacatc
    14881 ctccaagtat tatgttgttt tttcttgata ttagcagttc ataagcttca tctaaacttt
    14941 ttggaactac atattccttt atagttatca tactctctcc ccatatcaac ttaattttca
    15001 cttaaaagtc taagtgttta aatatttatg tattgctctt aattgacctt tatatcctgt
    15061 acatctacaa aggttaccat ttacataatc tataacttct tcttctgttg gattttgaag
    15121 ctctcttttc attgccaaga ccatcattat aaatccagga gcacaaaatc cacactggtc
    15181 agccccttcg tctgcaagaa aatctccaaa cttctttgct tcatccaaga caccctcaag
    15241 tgttgtaata tgctgacctt ctactctagc agtaagataa ttacatgaaa gcacggcctt
    15301 gtcatttacc atcactgtac ataacccaca tgagcctgta tcacaccctt ttttaacact
    15361 tacatatcca ttttctctta atgtatctgc taaaaaatca tctggtctta tacttaattc
    15421 tttttcttta ttatttatgg tacatttgat aatcaaataa atcacctcaa aactcatatt
    15481 tttaagctaa agttttacta tactttttta tgaataaatt acatttatta ataaaggcta
    15541 ttccatttat gaccttccat tctatttttt atagttcctc ttacacaaag tctctcagct
    15601 gtatcttgag catcttttaa tgctttctct tcattagctg tcaatatttt tgaatcttcc
    15661 attattatat ttccatctac tataacactc tctatatttt tcatactaga agaatatact
    15721 aatgtagata ccggattatg cataggtatc gcttttggtg aaagcattgg attaaatatt
    15781 aataagtctg cttttttacc tatctccaat gaacctatct catcttccat tccaatagct
    15841 cttgctccat ctatagttgc caactcaaga actttttctg ctgacattgc taatgggtca
    15901 cacttattaa ctttatgttg aagtgctgtt aatttcataa gttcaagcat atcttgagag
    15961 ttattactag cggctccatc tactcctaaa ctaactgtta ttcctttttt aagcatttct
    16021 ggcactggtg caacacctga agataagtac atattacttg ctgtattatg agacactttc
    16081 atatcgtatt ttttagtaag ttccatatct ttttcagtta gatacacaca atgtaccata
    16141 agcacatttg gtccaagtat tcctaatttt tctaaaacat ctatgtcata ttgcccatgc
    16201 aattcttttg ctgcttctct atcaaaagga gtctctgata tatgtactgt aaataaagca
    16261 tcatcatatt cttttactac tctccatagc atttcaagca tttcttgaga atttgaccat
    16321 attgctgcag gagctactcc tattttgatt cttccatttt ctgtattatg gtgtttttca
    16381 aacaatcttc ttacatcttt ttcaaccgtt tctacatctt gcattattcc aggatgaact
    16441 ccaaattgag ctcctgtatt catacatcct cttccaagta ttcctcttat tcctaattct
    16501 ttataagcat ctattattcc atcacaaaga cctggcttac tatgaggata catgtagtca
    16561 accattgttg ttataccact tctaagtcct tcaatacatc caagcattgc agcatcataa
    16621 gtatcttttg gctctaaata gttagctgct ggaaatgtca tagtttctaa ccagtcttta
    16681 agtaccatat catctcccaa tccttttaat aaagtttgga ataaatgatt atgtgtattt
    16741 ataaaacctg ggaataaaac tttaccttta gcatctataa tttttttaac atcagtatat
    16801 ttactttcta tctctttaga atttccaata tcagcaatct tgttatcttt tactactaat
    16861 gccccatcaa aaataacttc tctctcttta ttcacagtta ctattatggc attcttaata
    16921 agtatatcca tcattcttat ttccccccgc attatttagt aatttttctt ttaatatatt
    16981 gacctgttgg atgttcttta acattacaac tttgtactac atgatttcct ctcaaaaata
    17041 catcttcaac tttacattta accttaaatc cttcatatgg agtataatct acattttgtt
    17101 tttgagtttt ataactaatt gtttcttctt tattgatatt taaaatgact atatctgcat
    17161 cacttcctac agctatctca ccttttttag gatacattcc aaatattttt gcagcattcg
    17221 tagaagtaac ttccacaaac ttatttgcac ttattctatt ttctaagact ccatatgtat
    17281 ataaaagtgc taacctatgt tcaacaccag gtgctccatt tggtatctta ctaaaatcat
    17341 caattcccaa gtctttttgc cccttaaaat taaatgaaca gtgatctgtg ccaactgttt
    17401 gaatatctcc actagacaat ccttcccaaa ggtaatttat gtcttctttt tttcttaaag
    17461 gaggagacat tacatactta gcaccctcaa atttatcctt attatataaa ttgtcttcta
    17521 ataatagata ctgtgggcat gtttctacta tcatatctat atttttttct ctagccattt
    17581 ttacagtttc aagtgactcc ctacaactta agtggactac ataggatttt gaattagata
    17641 atttagttat atcagcaagt cttgaaacag actctttctc aactatgtta ggtcttgtaa
    17701 gtggatgata ttttggctcc aaattaccat tttgtatatt ttcttctatc aatacatcta
    17761 gtaaatcccc attttcacaa tgaaatccaa ctatacaacc taaatccctt gctttcttta
    17821 aaaccctgta tattgttcca tcatctactt tcatgccatc atatgccata tacatcttaa
    17881 aagatactat cccatccgaa ataagttttt ccatatgatt aaatgtatct ttatttaaac
    17941 atgtaattgt catatgaaaa ccataatcac aataacaatt tccacttgct tttttatgat
    18001 atgcttctac accttgcagt aggttttccc cctcattggc ttctgcaaaa tctagtattg
    18061 tagtagttcc tccagctata gctgctcttg ttcctgtttc aaaattatct gcagttgtaa
    18121 tagaacctgc attcatatca aaatgagtat gtgtgtctat tccaccagga attacaattt
    18181 tacctgtagc atcaataacc ttatcaccat ttatttctaa gttatttcct atttcaacta
    18241 tctcttcatc ttctatcctt aaatcactta tataagtctt atcagaggta attatagttc
    18301 cacctcttag tattgttccc atatatacct cctaactttt aagctttaaa gtattttcta
    18361 agtattgtaa aactttattt aaaattgtat tttctaaagg tgctatattc agcacctcta
    18421 gactatattt aaataattta ttgtgaacta aatattattt tccgtataca gattttaata
    18481 ttccatagta accttctgtt cctataaata actgttcttg ctctatatac tcatctattg
    18541 tgtgagcaag attttcctta gaaggaccaa atcctatagt ttttattcca gcttcacctg
    18601 catagtgact tccattcgta cagaatgagt attgagttat ttctgaatct attccagctt
    18661 cttttaatcc cttatatgct gcttgaacaa attcatcttc ttcgtcatat aaccaacctg
    18721 ggaagaatct ttcactttct atagtatttc ctgtatagca atcagctttt tcaactgcat
    18781 aagaaacttt tgcatttaat tctgggtctt ctttcatcat ttcatctaat aaagcttgta
    18841 ttggagctaa tacgccttct cttgtttctc caactaataa tcttctatca aaagtagctt
    18901 tgcaataatc tggcactact gatgctcctg gatatggaga agattttata tctgttaaaa
    18961 ctaatattcc atcacctaaa actggatgag ttggaggtac taattgttgt atcttttgga
    19021 ttacattagc cattttataa actgcattta cacctttttc tggattagca gagtgagctg
    19081 gtttaccaaa agtttctact actatttctc ctctacctct ctgaccaatc tttaagttta
    19141 actctgaaga ctcacctatt acaacatagt caggttgaac agccttactt atctctctag
    19201 ccgaaacacc ttcaaatatt tcttcatgaa caacacctgc tacatatagt tctccagcaa
    19261 aatctctatt agtgtcttta gcaaaatacg ctacagcaga catcattgca gtatattgac
    19321 ctttcatgtc agaagttcct ctaccatata tctttccatc aactattttt ccttcaaaag
    19381 gaggaacact ccatttactt gcatctggaa ctggaactgt atctatatgt ccatcaaata
    19441 atattttctt acctggcttg ttacctttta tacatcctac tatatttcca tatctatctc
    19501 ttgaccaact atcaaaacct aatttttcaa aagactcttc tattgctttt acaacacctt
    19561 cttcatttcc agaagaacta ggattttgaa ttaatttttg gcatatttca gttacttctt
    19621 gttttctttg ttcgtttaac atttcattat ccccctagat tttttataat gtatgtattt
    19681 tatatactta tatattttct aaattttaga acttatatat cttctaaata tgtaaaccaa
    19741 tatctaataa ttgcatttta gtaattcctt atatacttgg atattctcca tcccaaacta
    19801 tacttctata tttgtcaggg tcagtatctc cttctgtgct tattaaaagt attcttgaat
    19861 tttcatctaa ttttaaatct tttcttaaat ctgctaaatc ttctctttcc atagctgcta
    19921 ctaaaagacc agttgtaact gctccagatt ctccagaaat taccttttca tcaccattta
    19981 aaggattacc taatgttctc atacccttag cagaaaccca gtctggtgct gaaacaaatg
    20041 ctgctgcatg attttttaat acttcaaatc ctatagtatt tggctctcca caagcaagcc
    20101 ctgccattat agttggcata tctcctccaa caaatcttgg ttttccatct ccagcttctg
    20161 ctgatttata gtaacaatca gcttcatcag cctctactac tactgttatt gggcattcat
    20221 catatattga agcaacatac ccttgaactg caccagcaag tgaaccaact cctgcttgaa
    20281 caaatacgtg tgttggtcta tctactccat attcttttaa ttgctctata gcttcttgag
    20341 ccatagttcc atatccttgc attatccacg ctggtatttc ttcatatccg tcccatgctg
    20401 tatcttgaac cattactcca tggtcatcag cttctgcata atcattagct aatcttactg
    20461 catcatcata gtttaagtct gttatactag catctgcacc ttctccttta attttattta
    20521 atctaaattc agaagaacct tttggcatta atacaacaga tttttgacct aatttattag
    20581 ctgtccaagc aactcctcta ccgtgatttc catctgtagc tgtaaagaaa gttatttctc
    20641 ctaatttttc ttttatttct tttgaagtta atttgtcata ccctaactca gatatatctg
    20701 tatctaatct ttgagctaag tatctaccca tagaataaga accacctaat actttaaatg
    20761 catttaatcc aaatctataa gattcatctt ttacatatac tcctgcaaca cctaattttt
    20821 ttgctaaacc ttctaggttt gctaatggag tttctttata ttgaggaaag cttttgtgaa
    20881 aatttctaac cttagttatt tcttcttcat ttaaaaattt gatacaattt tccttatcgc
    20941 cctttggcaa attatttact ttccatttaa tttcttttaa catctaaaat acctccaaat
    21001 tattgttaaa tttttatact ttaatatata agcaattaac atgccaacac taaatatata
    21061 ctagatattt ttctatgact ctttagtata gaaattgcaa tgcttttatt attttttctt
    21121 ttctatcttt agttcataca atgtatgtag aatttaataa ctaaaaaacc ttttctatct
    21181 tctcactttt taattctcat ttttaaaatt taaaaataaa tctcaaaaca ctttgtttct
    21241 atatttttta atataaaatc tataaaatct aaattaaaac ataaaatagt gatgcaataa
    21301 tctattacat cactatttgt atatattcaa taatataata aatctttagt ggtctctaag
    21361 aggtgatttt tcatcttttt taacatctaa ttcttctttt acgacattcc atttttcaag
    21421 accaaactta gaaaccataa ctgcctctgc tgcacctttt ccaagtcttt ttactgtgtc
    21481 catacctgtc tcatcctctt gggcaccttt tgcttttcca tctttactcc atattgtacc
    21541 acctatatag catccaccta aacctccaga cactaacatt tcatgcatta ggaagaaatt
    21601 tattatagga agttttgtca attcttggcc accatatcta gttccaccag tagttatagc
    21661 tgcaccaacc ttattttgaa gttttcctgg atgaactaaa tacattggac gaagtctatt
    21721 aaatactgct gtaagttgag cagttatatt catatcataa actggagaac ctactataat
    21781 tccatctgcc tccaatattt tttgctctaa ttcttggata tcatctttta taatacacat
    21841 agtttctttt cttatacatg catcacaatg tacacaagga cttatttttt tccctctaac
    21901 tgaccaatac tcagtttcta taccaggtat agtttctgct tctttcaaag cttctaacac
    21961 tgcatattct gttgctcctt tacgtggact tccacaaata cctaatatct ttgccataat
    22021 aatatctcct caccaaataa atctattttt attatctatt tacaaataca ataaattgtt
    22081 atttctgctt taatttatac tattttaatt ttattggtaa tgaatgtatc tctacatcag
    22141 ttgcattata tactgcattt gcaacagctg gcgcaactgg tacaacggca cattctccaa
    22201 tactcttacc accaaaaggc ccagcttttt cataaccatc tacaaatgca acttgacatt
    22261 ttggcatatc tacagttcta aataatttat atgttttaaa atcagtagct ttaggtctac
    22321 cttgttcatc aaatgccaat tcttcactca atgcgtatcc tagacccata tgaatcccac
    22381 cttctaattg tccttctaaa tttagaggat ttataactct accaacatca tgtacagcta
    22441 caaaatcaac tacttttata tccttagttt ctttatctac taaaacttca gcaaaatgta
    22501 caccataaga agtacgtcca gctggtgaag aataatcttc aacaacagtt aactctctta
    22561 atgatttact ttgactatat actgcgacat cagaaagtga tgcttttaca ttttcatcaa
    22621 gtttactaat tacacatcca ttgtctagat ataaatcttc ttttgatgtt tcaagtaatt
    22681 tttctgcttc ttctaatata agatttttca atttctctgc tgtcttttta gctcctccac
    22741 cttctacaaa tacccctcta cttgcatagt caccaaggtt gaatgtacat gcatccgtat
    22801 cagtttcaaa tgtatcaact ttatcaggtg ttattcctaa aacttcagct accatcattg
    22861 tttgcatagt tacaacacca ttacccatat catgagctcc tgttagcagt gtcaacgtac
    22921 catcttcatt taatttaaga gtcaatgtaa caacatctct atgtgcacca aaaactccat
    22981 taccatgtgc acctattgcc atacctatac ctcttaaata ttttccttct tcttttggaa
    23041 gttttttctt ttcatcccac ttaaacatct tcttaccttg ctctatacaa tccaatactc
    23101 taggatttcc aagagaaccg tggaagatta tatcgacatc atctggctct actgcatttt
    23161 tattttgaaa atcgactaaa tccataccta tttcctttgc tattttcgca aattgagctt
    23221 gttgagccat aaatatttga ggtgacccat agcctctcat agctcctgct attggtgtat
    23281 ttgtatatac aggcatccca gtaaacttta tatttggtat tttataaact ttaaatactt
    23341 tatgactaag tgctcctata acatttaaag cacttgatgc atatgctcct gtatttgtat
    23401 atatttttat gtcttgtgct attacttcac catctttatt tacaccagtt tttaatttta
    23461 caaaagaccc atgacgagtt cttgttgata tcatagattc ctttcttgta agaaccattt
    23521 taactggtct tcttgtcatt tttgataatg cggctgctac tggttcaatt gtaagttcta
    23581 attttccacc aaatgagcct ccaatagcag gtcttataac tcttacttta tttaatgaca
    23641 tcccaaaaat ttgagatagt attattctaa atccaaatgt attttggcaa ggtgtatgta
    23701 cagttaattt atcattataa tcatagtgtg caattacact atgagtctct attgcactat
    23761 gatgtattgc tggagtagag tattcatctt caaatatata gtcacattcc ttgaagcctt
    23821 tttctacatc tcccccattt atgttgtttt gagaaactat atttgaatct ccatgtatgc
    23881 agatagcatc ttcttttatt gcatcttgta tagtaaatac agctggcaat tcttcatatt
    23941 caacttttat aagttttaca gctttctctg ctatttctgg agtctctgca gctactgctg
    24001 caacacggtc accaacaaat ctaactgtat ctgaaaatat aacttcattt tcaggtattt
    24061 tgtgctcata aaatcttaat gaaccattgt attttctttg tgatgtattg agataagtag
    24121 ctatagctct aacacctact actttctcag cttcacttgt atctatactt tttatttttg
    24181 catgtgctac agggcttaaa agcatcttag cgtaaagtac attttgtggt ttcatatcag
    24241 ccacgtattt catttgacca gtaactttta aagctgcatc ttttagaggg tatgattttc
    24301 ctattacctt ttccataatt atctaccccc taatctagct gcagataatt ttacagcttc
    24361 tataatcttt acatatcctg tgcatctaca gagattttct ttaaaagctt ctctaatttc
    24421 atcttcatta ggagatgcat ttctatttaa aagagcttgt gttgttataa tcataccagg
    24481 agtacaatat ccacattgta cagctccaac ttctataaaa gcttcttgta ttggatgaag
    24541 attttctcca ttagcaaaac tttctatagt gtatataact ttaccttcgc agttttttgc
    24601 aagaagttta caagatttca tgtcaactcc atctatcaaa actttacatg ctccacaact
    24661 gccactatta caaccttgtt tcgctccagt tagatttaat ttttcacgaa gtacatgcaa
    24721 aagagtttca ttcttttcaa cttctatttc atacatgtaa tcattaatat ttaattttat
    24781 tttttccatt ttctcctcct acagataaac taatgttgta atagaatatt attacaatct
    24841 tattttaata ttagtataag ctattccact tatgtccttc cattctatta gttacattag
    24901 ctctcttaca taattcttct gctgcatgtt gtgcattaag caacacttgt tcttcacttt
    24961 caattgtagt tacttttcca ttttcaagta ttacatttcc atcaactaaa acactctcta
    25021 cattgtgcat actagctgag tataccaaag ttgatacagg attgtgaaga ggtattgatt
    25081 ttggagaaag cattgagtta aatattacta ggtcagcttt tttcccaatc tccaaagaac
    25141 ctatttcatc ttccattcta agagttcttg ctccctcaat tgtagccatt tcaagaactt
    25201 tctctgcaga aattgccaga gggtcacaat tatttacttt gtgttgtaaa gctgttagtt
    25261 tcataagctc taccatatct tgtgcgttat tacttgctgc accgtcaaga cctaaactca
    25321 catttatacc tttttttaac atttctggca caggtgcaac accagaagca agatacatat
    25381 tacttgctac attatgagaa acttttatgt catacttttt aagcatttcc atgtcttcat
    25441 cagttataca tacacaatgt actgctacaa cttctggacc tactataccc catttttcaa
    25501 gtaattttat atctatttct ccatgtatat cctttgttgc tgttcttgca aattctgttt
    25561 cagatatatg aactgtaaaa tatgaatcat attctttaac tatattccaa agcatcttac
    25621 ccatttcttc agatatagcc cacattgaag aaggagctac acagattttt attcttccat
    25681 tttctgaatt atgatatttt tcgaataccc ttctcaaatc tttttcaacc gtttccacat
    25741 cttctataag ctctttgtga atacctaaat ctatacaacc tctacctaca acccctctta
    25801 tgcctaaatc tttatatgcc tttactattc catctgtaag tcctggtcta ttgtgagtat
    25861 gcatataatc aaccattgta gttataccac tttttaaacc ttccatacat ccaagcattg
    25921 cagcatcata agtatcttgt tctgttaaga attttgctga tggaaacatc attgtattta
    25981 accactcatg aagtgccata tcatcaccta aaccttttaa taacacttgg aacaggtgat
    26041 tatgagtatt tataaagcca gggaatatta cttttccatt agcatctata acttttttag
    26101 catcaagata cttaggctcg atatcaactg tatttcctat gtccaagatt ctgtcacctt
    26161 gaatagctat tgctccatca aatataacat ctctgtcttt attaactgta acaattattg
    26221 cattttttat tagtatatca atcatcttaa atcccccttt gaatactttc attacaacat
    26281 tttaccatat ggttttctca tattatatct aatacattta tccaatattt tcttcaagat
    26341 ttgaagtaac gttttcagca cttttacgtg actttaattt aaataatgtt tgaagtaata
    26401 tagctattat tgctccagaa actatacttg accctccaag gacagttcca attgtttctg
    26461 ggaattggtc taaaacttgt ggagcagttg taagacccat acttgttgct atagatacac
    26521 ctgctataag attgttttct tcagtgaatc catccatact cataatagag aaaccagaca
    26581 ttgctattga tgagaaaact actaaagttg ctccaccaac aacacaagat ggtatagttg
    26641 tcattattgc acccaatgct ggagatatcc ctgctagtaa taatacaagt gcccctagtg
    26701 ctattacaaa tctacttgta actttgttca tagatacaat tgctgtattt tggctaaata
    26761 ctccagttgg aagagctgca aatagtgatg aaattataga agttatagaa tttcctaata
    26821 caactgatgc taattcttcg tcagttacct ctctatccat tgctcctact gtagctattg
    26881 tacaggcacc catcatatca gctataccta ttatgtaaat aatagtaaac attactatta
    26941 actctggtct aaattctaat ccaaaagctg ctggtgttgg taaagatact atagctgctc
    27001 cttgaacggc tgagaaatca accaatccta aaactaaaga tatagcataa cctactaata
    27061 ttcctattaa tattgaagaa ttttttacta aacctttacc gtatttattt atcattatta
    27121 ttacaaaagc aactataact cctactgtga agtttattgg gcttccaaat gtttgtgtgc
    27181 cttctcctcc agctaaattc tttatagctg ttgcgaatag tccaagtccc atacatgcta
    27241 ttatagttcc agaaactatt ggagtgaata tatgtctaat tttcttaact ccaaatccta
    27301 caaagaatac gattacccca gcagcaatct gtgctccaaa tagagctgct aaaccatctt
    27361 tagctgctac tgaaagacaa gctcctaaaa atacataact cattcccatc attacaggta
    27421 atcttgaacc taacttaaat cctttaaata aaggtattgg atataactgt aaaaacgttg
    27481 ctaaacctgc tgctaacata gaaccctgaa tcaacattgt tgcttgcccc tggttaagtc
    27541 ctaccacgtt tgctattaat atcgcaggta ccatatttcc tactatcatt gctaacagat
    27601 gttgtaaggc caaaggtatt gattccttta gtggtggtat cccatcgaca tcatattttg
    27661 aagtattacg tgttttcata aaataaatcc tcccatacat aaatatcttg actaaatatt
    27721 tttataatta ttttctataa atatttttat gaccatgaat ttattgctca accgataaac
    27781 acagctaaac tgagctattt ttataaaaaa ttaacaaatt tctaaatatt gcctccccga
    27841 ttttcaactt aaatgaacat taattgcctg gtatatattt atttgttaaa ttttttatta
    27901 aaatgaatag ctatcaaaaa taatctaaca atctcatact aaataattta aacaattctt
    27961 ttaaattatt atatcttaat tagtctcttc cataacagct ctttctttag cctcatcctc
    28021 tagactttta tttggtatta ttagatttaa aacgaatgca accaatgttg caattactat
    28081 tggagattct ccaaatacta actttacaaa tgaaggaaat gcctcttggg ctgctgggac
    28141 tgatgttatt cccatgccta aggcaattgc caaaccaaca atggtaatat ttcttgatga
    28201 caactcttct gtaataatta actttatacc tgtcattgtt attatactaa atatagatat
    28261 tgtagctcct cctaaaacag aatatggtat agtagtcatt aatgcaccaa atttaggcac
    28321 aaaccccgac aataacataa atataccagc tattccaagc acaaatctac ttattacttt
    28381 gttcatagct accatcccca cgttttggct atatgatgat ggtggtaaac ctccaaacaa
    28441 agctcctatc atagtacaaa ttccacttcc tattactcca cttgataatt ccttatctgt
    28501 gatattccta tccatgcctc ccattgtagt agctgataag tctccaattg cttgaacagc
    28561 attgattata cttacaatta ctactgagat tattacaggc atatcaaatt ccatcccaaa
    28621 ttcaagcggt ttaggtatcg caaaccaagt tgcctctcta atagggtcaa aatttattat
    28681 acccagaact aaagatacac aatatccaac tataattccc aaaaatattg ctgccaattt
    28741 tgcatatcct tttgcaaatt gactaagacc tataactacc actaatgtta tagccgctac
    28801 tgcccagttt tgcatagagg cataagtagg actatttaca ccacctgcca tataatttat
    28861 tgctatagga tacaaagata atccaattgt aaaaaccact gttcctgcaa ctatattcgg
    28921 aaaaaatttt cttatctttt ttatgaatat ccctattaat actgtagcca ctccccctat
    28981 taattgtgca cccaaaatgc ttgctaatcc ataatttcct ccgactgcta caagtgttgg
    29041 tacataagta aaaccaactc caaaaattat aggcaatctt gaaccaatat ttcctattgg
    29101 atatagttgt ataagtgttg atataccagc tattattaat gcatattgca ctaaaagtgt
    29161 tatttgtgta gggctaacac ccacagctcc tcctacgact ataggtactg taacagttcc
    29221 aactatcatt gctagtatat gttgcattga tagtggcaaa cactttaaaa ttggtggcct
    29281 tccatcaata tcaaacatag aaacattctt ttgatattta ctcaaggtta tcactcccaa
    29341 ctatttttta atgacagtta ttattatctc acacaacatc ctttcttttt ttattttgtc
    29401 atctcaactt aatatgaagc aattataatg ccaatttttt aacataattg ttttacatat
    29461 ataattttta ttatatttgt tagtatttga taatttatta aagcatttat ttttttaaat
    29521 tcttttaaat tttttttatt tttggataat aaaatgctat tacacaaaaa aacacttaga
    29581 aaatagtttt ccaagtgttt tttatcaatt ttataatttc aaattttaga attgagaata
    29641 aaaagcctaa ttattataca tctatttttc tgtacaatgt agctagtgat attccaagtt
    29701 ttttggcagc cagtttttta gacttagtat catttccgta aaactttaac actttcttta
    29761 tataggctct ttcaaactct tcaagtgtaa gtatgtcttg ttccatactt atctcatagt
    29821 cactttcctc aagtaacttt atatttatat tatttaactt aaaatattca agtatctttc
    29881 tatttattat tcctttatgt attattccat cttcctcaag aaggtttaat gccagttcta
    29941 tagtattttc caactctcta atatttcctg gccaaggata cttaagcaac atttgttcca
    30001 catctggctc tatatggtac acgtttttct tcatctttct cgaatatttg tctataaaat
    30061 tgtttattaa tatttgtata tcgtctcctc tttctctaag tggaggcact tctaaaggta
    30121 ttacattcaa tctatagtat aagtcttctc taaatttatt ttccttaacc aactcaaata
    30181 aatctctatt agtagctgat atgattctaa catctatatc aattagttca tttgaaccta
    30241 ttctcgtaaa cttcttttcc tgtaataccc tcaataactt tgattgtagt tgaattggca
    30301 tatctcctat ctcatctaaa aatacaaccc ctccattggc caattcaaac ttaccaattt
    30361 taccttttga atctgctcca ctaaaagctc cttttgtata tccaaaaagt tcactttcta
    30421 gtaaaggttc tggtatagca gcacagttta tagcaacgaa tgttttattc cctctgtttc
    30481 ctgcgagatg aatggctctt gctattaatt cttttccagt gccactttct ccagttatag
    30541 ctacagtaga atcactattt ccaattttac aaattctatt cttaagagca cgcattacat
    30601 cagactctcc aattatggag tctactgttg ttgttcccca aatattatat acttccattc
    30661 caccatacat tactgaatca ctgtgtttgt ccataaaata tcaactccaa ataagtattc
    30721 tatataataa tcattcacat tatctattta attatatcat aacagaaaag cttagttata
    30781 atttaataat attattttaa aacaaaactt aataaaaagt atatctactt agttttaatt
    30841 tgatagatat actttcttca ttttacaaaa atgctctatt aaataagcaa ttacaatgcc
    30901 atattttata tggaaataat ttttaaaatt tttaatttaa gttcttatta aattttttat
    30961 actactcgta atttttatac ctatataaaa ttacttttat aaattttaaa attcttattt
    31021 ttaaaattta taattaaaaa ttatcttttt taaatcattt tttgtgtttt ttatatcatc
    31081 taacctcaca gtttttgctt ctataaactt acccttaaat gattctgata atttccagga
    31141 actataattc ttatcttttt gaatacaagg atataataat atacatcttt ttgcattttc
    31201 atatgctgtt atatatgcat acatctggta tatatcactt gacctataaa aaacatttga
    31261 atctacttca atagctttcc atttagtgtc aattataatt tcatattcat tttttaagtc
    31321 atataaaact atatccggtc ttaaattaaa gtttttctta cctgtttgtt catttttcaa
    31381 aagaaattta ctcttatctt gtatatatgt ttctctaaat gaattgtccc atatactttt
    31441 gattaaaatt cctatatatt cttcatacaa agtatttatt tcaaataata tagaaaatgc
    31501 ctcttgatta ttttgactat tatccataga caaatttaaa agtataagtc tagctagtaa
    31561 ataacaatct ttaaatctat cattgttttt ataaaattta taatccaata gtttttttct
    31621 atctatataa attaaatcta cattttgaaa atagcttaaa atttttttaa tcttgccttg
    31681 aattgaattg tcatttattc tacataaaat agatatacat gcttttttaa gaacttgatt
    31741 caagaaatta ttttcactat actcatcata ttcacatctt attttcattg gagaaatgcc
    31801 tttttctttt gcatatgtac ttaataatat tttacccctc ataacattta agttctctat
    31861 tttatttata tattcaaaat aaataccttt tttcatctgt gtttgcatac tctcaatgaa
    31921 atacataaca aaaaaattta agagattata atttttcaaa ctcaat
//
LOCUS       DAEPHU010000047        31912 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 01A10CD0081
            SAMN05941466-rid12468953.denovo.047, whole genome shotgun sequence.
ACCESSION   DAEPHU010000047 DAEPHU010000000
VERSION     DAEPHU010000047.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941466
            Sequence Read Archive: SRR6291087
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 31912)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 31912)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068158.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 22:43:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,892
            CDSs (total)                      :: 3,805
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 87
            rRNAs                             :: 8, 1, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 55
            CDSs (without protein)            :: 55
            Pseudo Genes (ambiguous residues) :: 0 of 55
            Pseudo Genes (frameshifted)       :: 21 of 55
            Pseudo Genes (incomplete)         :: 28 of 55
            Pseudo Genes (internal stop)      :: 16 of 55
            Pseudo Genes (multiple problems)  :: 8 of 55
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..31912
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941466-rid12468953.denovo.047"
                     /strain="01A10CD0081"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            <1..1169
                     /locus_tag="KR231_002280"
     CDS             <1..1169
                     /locus_tag="KR231_002280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="EAL domain-containing protein"
                     /protein_id="HBH0004647.1"
                     /translation="KFKYINDLFGYEVGNEILRNLTKIIKRNIFEEEMFARISADNFI
                     IIMKYIEEEDITKRLKTIFEELDLFNNNQEEKYKLVLSCGIYFILPEDRDINSIIDRA
                     NIPHKMAKGGHKSSYAFYDNKIHDQEIKEKEMENTMFSSLENKEFIIYLQPKIELNTG
                     EIQGSEALVRWKRPDKGLIPPNEFIPFFERNGFVINLDLYVLEEVCIYLRKWIDAGIN
                     PVTVSVNVSRIHLYCNNFIETYKNIIDKYNIPAKYIELELTESIIFDNFDILIDIMNN
                     LKKIGFLISMDDFGSGYSSLNMLKEIPMDILKLDQKFIMETYNSKRSKIIVTKVIEMA
                     KELGMKVISEGVETEEQFKLLKEVKCDMAQGYLFGKPMPIEEFEHLIVSNLVRG"
     gene            1345..1713
                     /locus_tag="KR231_002281"
     CDS             1345..1713
                     /locus_tag="KR231_002281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBH0004648.1"
                     /translation="MEWELDNNKPIYIQLVEHLKLKIISGEIKIGSKLETVRALAEDA
                     EVNPNTMQKALTELERQGLVYSQRTKGRFVTDDKEKIKAMKEEIANVEINTLKVTLEK
                     LGYDRDEMLKLITENLKGEL"
     gene            1715..2440
                     /locus_tag="KR231_002282"
     CDS             1715..2440
                     /locus_tag="KR231_002282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH0004649.1"
                     /translation="MDKNISNVSQDGIVEFKGVNKSYGTKNVLKNIDLNIPKGKIVGL
                     LGPNGSGKSTMIKLMNGLLQPDNGEIMINGMKPSIDTKKIVSYLPERTYLNDWMKVSD
                     LLKFFYDFYSDFDVRRANEMIKSLDIDVNEKLKTMSKGTKEKVQLILVMSRNASIYIL
                     DEPIGGVDPAARSYILKTILKNYSEDSTLLIATHLISEIENICDEIIFISKGEIVLQG
                     DVEAIREEKGKSIDALFREEFKC"
     gene            2434..3198
                     /locus_tag="KR231_002283"
     CDS             2434..3198
                     /locus_tag="KR231_002283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBH0004650.1"
                     /translation="MLGKLLKYELKASGRIFIPLYIAILIVAVFNGIFMNTNILQVQG
                     IGILVLTSLFMALGVLTIVVTIQRFRKNLLGDEGYLMFTLPVSTSSLILSKCITALIY
                     AVLSFIVAVFTFGVLMLFGTSGILLPEILDLFNTSFKWISENFLDILLLVVVMFISYS
                     SFILLLYTSISMGQLPKFNKHRNIVAFASFIAINIVISIVGDAVGSILPNEDTNMVYH
                     LYQSPSFMLAILGSLVVAIALFFATKFILDKKLNLE"
     gene            3420..4670
                     /locus_tag="KR231_002284"
     CDS             3420..4670
                     /locus_tag="KR231_002284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBH0004651.1"
                     /translation="MKSYTKAKWSVWGIITFSFVLVLFLRMSTAVVSDNLANELGFNS
                     IQISNIASFCLYAYAFMQIPAGILIDKYGARKISSLGIIMASLGSILFGLIQSIELAY
                     ISRVIVGAGTSVILLCILKIQGRWFNKSEFASATAKFSFVGNLGGVLATFPLVFLSEL
                     VGWRNSFLLIGIIGVVIGCFMYIIVRDTPKEYGFNIDTEPYEKSEKVNIVDGIKSVIK
                     NKSTWYNSMIMFSFVGLTSAFISLWGVRYIMDVYGVSKSFSAFIVSFFTYGFIFGSII
                     MDFVFAKIRSSKFNIIKFGAMIDLFIWIVIVVVYQVKPPIIVLPISFFIMGCIVMSHL
                     QVFNDAKYKNKEIYSGLATSVINTFEFIGSGIINLIIAISLQVNSYNIVDGYKKGFVV
                     FIVLSIITIVSSHIGVKNDDFKAI"
     gene            4863..5747
                     /locus_tag="KR231_002285"
     CDS             4863..5747
                     /locus_tag="KR231_002285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mechanosensitive ion channel"
                     /protein_id="HBH0004652.1"
                     /translation="MDTTKIDDISKLDLNNLDINKMDMGGIMESLLEWATTSGVKLII
                     GILILSIGFKIIKKFVNHVMLLLSKRDIDLTLRRFLKSLLLSVLKVAVIIIVLEYWGM
                     SLSSFAAVIASAGVAIGLALQGSLSNFAGGFIILLIRPFKVGDYVEAAGHGGTVEQIG
                     LFYTQLVTPDNKQILIPNGSVSNDSLINYSAKNTRRVDLTFSVGYEDDILHVRRVLKD
                     IVNNHKLIINEPEPFIGVVEHGDNAIKFATRVWCKTEDYWTIYLDLLEEVKVRFDEEG
                     ITIPYPKMDLTVKELNKI"
     gene            6106..6723
                     /locus_tag="KR231_002286"
     CDS             6106..6723
                     /locus_tag="KR231_002286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PepSY domain-containing protein"
                     /protein_id="HBH0004653.1"
                     /translation="MCKKMYLLVVGILIAGLLTACNGSPTKDSEQAQDNTKKEANVSN
                     NALKDEKNNENLMEQDFKVPYTDAINIFKDKYKDADIVDLSLERDLNKFVYTVEGVDD
                     NNEYKMKIDANTKDVLEDKTEKLDSEDLNGVARKEKLDFNDIMTPQQAMEIALKEQNG
                     MVKEWSLDKDLDVTFYKIRIDKDKNEYDIKVDSKKGTVLKVEKED"
     gene            6831..9362
                     /locus_tag="KR231_002287"
     CDS             6831..9362
                     /locus_tag="KR231_002287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HBH0004654.1"
                     /translation="MSLKSLKIKENLYWVGSLDPDLRVFDIIMYTPYGTTYNSYVLKG
                     TEKTVLFETVKDKHFDNYIERLNDLNIDFEKIDYIVVSHTEPDHAGSVEKLLDLAKNA
                     KVVASETAIKYLKEIVNKDFEYVAVTDGDTLSIGDKTLEFFSVPMLHWPDTIYTYIKE
                     DKTLVTCDSFGSHYSNDKIVNTLDEDEEKDYLDALRYYYDCIMGPFKPSMVTAIEKIK
                     DLDIDTVCPGHGPVLTENPRKIIDLYYNWSVNEQIKLEKEVTICYVSAHGYTKIMAEA
                     IKAYIEKNSNYKVNLFDVIEHKQEDILAKIAVSQGVLFGTPTILGDALKPIWDILISL
                     NPVLHGGKVASVFGSYGWSGEGIENAMERISQLRMTAVKPFAVNFKPSNEEIDKLHSY
                     TGKFLDKLNSTFGSKKKTKKFKCVICNEVFEGDSAPSVCPVCGAKEDQFIEVEEDEVT
                     FRKDTDEYFVIVGNGAAGFYAADAIRKRNKTCKITMISNEDELTYYRPALSDGINEEL
                     GSDFYMEDKDWYDKNNIVVILGTNVDKLDEVNKTIIVNDGAIKFDKLVIATGSRNFIP
                     PIKGHDLENVFTLRNIKDLYSVKEALEKSKKVVVIGGGLLGLEAAWEFRLKGLEVVVV
                     EAMDSILSKQLDKEGSKILEQCVRDTGIDVRLGVAVDGIEGDGKAQKVVFKDGDSVDC
                     DMVVFSIGVRANTQMVQDTSVKIDRGIVVDKTLQTNVKDIYACGDVAQVGNISLAIWP
                     SSVEMGKIAGANASGDNLTFESEVYPVSLDAMNVKVFSIGNIQNFDKEISSKDEGQRI
                     YKKLFMKDGSLVGAILINDLSCTVKLIRLISEKGDFEDIMKADIL"
     gene            9796..10497
                     /locus_tag="KR231_002288"
     CDS             9796..10497
                     /locus_tag="KR231_002288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_021418928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanG-Cd-type vancomycin resistance DNA-binding
                     response regulator VanR"
                     /protein_id="HBH0004655.1"
                     /translation="MNENILIVDDEKEIADLIEVYLKNEGFTVYKFYTGKEALECIES
                     KNLDMAILDIMLPDIDGFHICQKIREKYYYPIIMLTAKIEDIDKIMGLTIGADDYITK
                     PFNPLEVVARVKTQLRRYMRYNNSYEQQSIIVNEYDIKGLIINKETHKCSLFGKEVAL
                     TPIEFSILWYLCEHQGKVVPSEELFEAVWGEKYLDNNNTVMAHIGRLREKIHEPSKNP
                     KFIKTVWGVGYTIEK"
     gene            10547..11629
                     /locus_tag="KR231_002289"
     CDS             10547..11629
                     /locus_tag="KR231_002289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HBH0004656.1"
                     /translation="MRTALMAFIAIIFIWILYSFILYGKFSIWIVSFFENAFRMEYKA
                     ALNLYQQIFRNSMELFMILAMVIVFFIIFRVYLNWFTKYFSEINQGIDSLIKEDVGEV
                     ALSPELLAIEKKINSIKHILEQRKFETQMAEQRKNELIVYLAHDLKTPLTSVIGYLTL
                     LRDESQISEELRKKYLSISLDKAERLEDLINEFFEITRFNLSNISLEYSTVSLTRMLE
                     QLTYEFKPTLMSKNLKYTLNVTPNMMIRCDVNKMQRVFDNLLRNAVYYSFEDTTIEIT
                     AVQEDDYIKLKFINHSNTIPEEKLERIFEQFYRLDTSRNSNSGRAGLGLAIAKEIVEL
                     HNGTITAHSENNIITFKVIIPIVGNL"
     gene            11890..12990
                     /gene="vanG"
                     /locus_tag="KR231_002290"
     CDS             11890..12990
                     /gene="vanG"
                     /locus_tag="KR231_002290"
                     /EC_number="6.3.2.35"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_021418924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--D-serine ligase VanG"
                     /protein_id="HBH0004657.1"
                     /translation="MNNKKIAVIFGGNSTEYDVSLQSAFAVLENLNTEKYDIIPIGIT
                     REGNWYHYIGDYNNIQNNTWFERDTDIIPVIVSQNRVKNGIIEFLIPDAVSQNHIPNS
                     AIESCENDIKYTKLDFVFPVLHGKNGEDGTVQGLFELAGIQVIGCGTLSSALCMDKDK
                     SHKLVHSEGIKVPKSILLKYSDKFNVAELSKDLTYPLFIKPVRAGSSFGISKIYKKEE
                     LQVAVDLAFEHDNEVIIEENIDGFEVGCAVLGNNDLLVGRVDEIELSKGFFDYTEKYT
                     LKSSKIHMPARIDLDCEKRIQETAKIIYRTLGCSGFARVDMFLTPSGEIIFNEVNTIP
                     GFTSHSRYPNMMKGIGLSFEEILDKIIEVYIK"
     gene            12987..13793
                     /locus_tag="KR231_002291"
     CDS             12987..13793
                     /locus_tag="KR231_002291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M15 family metallopeptidase"
                     /protein_id="HBH0004658.1"
                     /translation="MMNNILLDKNKEDKMTNTILLTKDKVYDGNLILVNAFLPVKTSE
                     DIDLIPVDTRFPSILMKREATNILQNILKSICGINEIVPVSGYRTAEEQQDIYSSSLR
                     DNGKDFTKKFVALPNHSEHQTGLAIDLGLKKEVIDFICPEFPYNGICNEFRKAALHYG
                     FIERYQCKKEEITGISQEPWHFRYVGYPHSEIINKMNLALEEYIEYIKRFSYTNCLKI
                     EDKEKIIEIFYVPIHTKEEVRISIPEQCVYQISGNNKDGFIVTFWRNRKD"
     gene            13811..15949
                     /gene="vanT"
                     /locus_tag="KR231_002292"
     CDS             13811..15949
                     /gene="vanT"
                     /locus_tag="KR231_002292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_021418922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine racemase VanT catalytic subunit"
                     /protein_id="HBH0004659.1"
                     /translation="MIRNKSYAGLDYFRIIAALLIIAIHTSPLLSYSKMADFVLTSII
                     ARIAVPFFFMLSGFFLISTYNYNCNKLKSFLKNVLFIYGIAIVIYIPLNIYTGYFSMN
                     NLVPNIIKDIVFDGTLYHLWYLPASIIGASIAYFLVKKLGLKYSLVITIVIYVIGMFG
                     DSYYGFLEKIPLLKNLYGYIFEVSDYTRNGIFFAPVFFILGGIISNKSNYMSTKNSLI
                     GFLISFLLMLCEGMFLHKLGVQRHDSMYIMLLPCMYFLFTALTFLKGSRARLLRTSSL
                     IIYIIHPMMIVVIRMFSKIFGIQTVLVDNSLIHYIVVSIASFIASIIIILILKPLKKD
                     LKGEHKVNTNRAWIEIDLNNLEHNVKMIQKAMPEDCELMAVVKANAYGHSAFEVATCA
                     NQIGVKAFAVATIDEGIDLRRYGILGEILILGYTNPIRAKELHKYNLTQSVIDLNHAI
                     SLNKQKYNIKSHIKIDTGMHRLGFDVNDVRSILKAFKLKYLDICGIFTHLCVSDSLKD
                     EDVDFTNKQIECFYKLIDFLLKKGIKIPKVHIQSSYGFFNYPNLKCNYVRIGIALYGI
                     LSFPNDTTKLQLDLRPVLSLKSQVILIRKIQKDDSFGYGRVFIASRDSVIAILSIGYA
                     DGIPRNLSCGKSYVIINGCRAAIVGRICMDQLAVDITDIPNVEVGNTAIIIGRDNLSE
                     LSVSEVANNSCSISNELLSRVGRRLNVIKK"
     gene            16263..16883
                     /locus_tag="KR231_002293"
     CDS             16263..16883
                     /locus_tag="KR231_002293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TVP38/TMEM64 family protein"
                     /protein_id="HBH0004660.1"
                     /translation="MQYIQELLDLTQNYWVLATIIGLLSAFIESFIPALPLVAIVTAN
                     AAIQGLFIGCLLSWIGSGLGTTSLFLLISRFNDSKLFNKLRNSKTEKAISWMDKQGFK
                     LLFIAYACPFMPGCLVTIASAFGKKDLKDFVPAMLAGKFVMFIVISYVASDIEGFITS
                     PLKIASFILLVFLSWKIGNRVNKNLENHNYDFHHKKHHNDKDDKMI"
     gene            complement(17049..17585)
                     /locus_tag="KR231_002294"
     CDS             complement(17049..17585)
                     /locus_tag="KR231_002294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent hydrolase"
                     /protein_id="HBH0004661.1"
                     /translation="MIKETHERGGYIFALLILPFINNLYLVKYDIAYKIVLIIIYIYF
                     AYLGSLFPDIDMRGSYISKKFMLIYKLFGSRFRHRGFTHSLIALLLIYSFFKSLTIFT
                     NNNIVFSCLSSGFIIGYLSHLCLDLITKEGIELFYPITINISLLPIKTNSKTEKFISK
                     LLNFIVIFLIGYQFYILL"
     gene            complement(17698..18372)
                     /locus_tag="KR231_002295"
     CDS             complement(17698..18372)
                     /locus_tag="KR231_002295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000094049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="superoxide dismutase"
                     /protein_id="HBH0004662.1"
                     /translation="MSLFIISQCITSFAFTPENNKFKVKPLPYAYDALEPYIDKETMK
                     LHHDKHYQAYVDKLNAALEKYPELYNYSLCELLQNLDSLPKDIATTVRNNAGGAYNHK
                     FFFDIMTPEKTIPSESLKEAIDRDFGSFEKFKQEFQKSALDVFGSGWAWLVATKDGKL
                     SIMTTPNQDSPVSKNLTPIIGLDVWEHAYYLKYQNRRNEYIDNWFNVVNWNGALENYK
                     NLKSQD"
     gene            18575..20449
                     /gene="asnB"
                     /locus_tag="KR231_002296"
     CDS             18575..20449
                     /gene="asnB"
                     /locus_tag="KR231_002296"
                     /EC_number="6.3.5.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine synthase (glutamine-hydrolyzing)"
                     /protein_id="HBH0004663.1"
                     /translation="MDGNISIYYKGDISKKEDIKFKIKESVNNTRLSSRIEYKDEEKT
                     FDFERFNVIDAIYGNKPFEKDGKVIVFNGNIYNYHEIKEELIKKGHNFTTNDDIEVLL
                     ASYIEFGKNCVHKIKGMFNFIIYDRENESIFGARDLFGIKPLYYINKENAIIFSSEYK
                     FLLEYMKNLNINERSLQSYFSFQYVLPEDTMIQGIRLIPAGHYFRVENGILSLKRYNK
                     LEFRSSTKFFYTKNHLGNRDVNEDDIRNIVVDSIVTHMEEEKEIGTFLSGGIDSSIIT
                     TVASQINPNIKSFSAGFSVKGYSELEVAKKTADKLGIENIQINITQDEYIKSLPNVIY
                     SLDDPIADPSEVGLYFLIKEAGKHVKVALSGEGADELFGGYNIYKEYSTMKSVVNSPT
                     YIKSILGRVSELMPNIKGRNYLYRATTPLEKRYIGNAKVFENSEVKRFFFKYKEKNIY
                     EYLLSNLYRDAQKNNYDYISKMQHIDVNTWLQGDILQKISKLSTAEQVELRVPFLYKD
                     VFDVAKNLRMEQKINKNNTKVLLREAFREIVPEHVVQRKKLGFPTPIRVWLKDSLGDI
                     VKETIYNSNVDEFIDKKYAIKLLDTHLKGHRDNSRKIWTIFTFCLWHQLFIEHKNVEY
                     "
     gene            complement(20541..21977)
                     /locus_tag="KR231_002297"
     CDS             complement(20541..21977)
                     /locus_tag="KR231_002297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trypsin-like peptidase domain-containing
                     protein"
                     /protein_id="HBH0004664.1"
                     /translation="MICTIKPLKISIKKSTEPLIEFISDTTYKNKRSSYIKEVYFTRY
                     IGVDDSIDKYIEKIKNIDTYFFNNPTIPYIRLNNLKINFDKEQTDKMLKIFNIYNSSK
                     FNSWDLYNIDFPCKIENDTLNWTKKIAFKNTLDLFSTSMPNCTSSIIKNFAVKLLCWI
                     DYFLPKLFYNKVKTTISPKIVYFGNIKRQELFFLYFLSQLGCDILYINPNKDILDLYP
                     ECSKFSTLFELSRKTPNILEIPFERHITNINYSENTNKTSPTTNKPNSKNTLNNTNLT
                     SKKIVQDEEVELSYEDLAKLSASVVMIVVCNNENKPFKSGSGVVINNEGYILTNLHVV
                     NDGYSFLVRFENDDKVYTSYQIIKYHSDYDLAVIKVDRKCKPIPVKVSKKPVRGQKIV
                     AIGSPLGLFNTVSDGIISAFRDFETVQMIQFTAPISSGSSGGALLDMFGNLLGLISAG
                     YDDGQNLNLAVESNLVKIFANNFIEIVN"
     gene            22306..22884
                     /locus_tag="KR231_002298"
     CDS             22306..22884
                     /locus_tag="KR231_002298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_126936537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TerD family protein"
                     /protein_id="HBH0004665.1"
                     /translation="MGITLSKGQKVDLTKGNPGLKNILVGLGWDTNKYDGGFDFDLDT
                     AAFLTGASGSVTNDGDFVFYNNLKHTSGAVEHLGDNRTGEGDGDDEQIVVDLSKIPGE
                     ISKISFTVTIHDATERRQNFGQVSNSYIRIVDKDTNEELIKYELGEDFSIETAIVVAE
                     IYKHNGEWKFNALGSGFEGGLAALCGNFGINL"
     gene            22923..23501
                     /locus_tag="KR231_002299"
     CDS             22923..23501
                     /locus_tag="KR231_002299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_126936537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TerD family protein"
                     /protein_id="HBH0004666.1"
                     /translation="MAIVLKKGQKIDLTKGNPGLKNIKLGLGWDTNSFDSGYDYDLDV
                     SVFMVGESQRVEKDEDFIFYNNLKHPSGAVEHLGDNRTGEGDGDDEEILVNLETMPKH
                     IQKIAVTVTIYEAAERRQNFGQVSNSYIRVLNSENDEEILRYDLGEEFSIETAITVCE
                     IYKYNGEWKFSAVGAGFEGGLEALCRNYGLNV"
     gene            23587..24216
                     /locus_tag="KR231_002300"
     CDS             23587..24216
                     /locus_tag="KR231_002300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TerD family protein"
                     /protein_id="HBH0004667.1"
                     /translation="MSINLSKGDKIDLKKSNPGLSNILVGLGWDPVQQSGGGFFKSLF
                     GGGQADIDCDASVFMLNQEGKLSGIKDLIYFGNLKSACKSVLHTGDNLTGEGTGDDEQ
                     ILVNLDKVPSNIHKLLFVVNIYNCVDRKQHFGMIENAYIRVEDQGNKKEIAKYNLSDN
                     YSEKTTLIVGAIYRKDGSWQFKAIGEGTKDAGLKEVMQNLERIECAYGI"
     gene            24206..26965
                     /locus_tag="KR231_002301"
     CDS             24206..26965
                     /locus_tag="KR231_002301"
                     /EC_number="7.2.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="calcium-translocating P-type ATPase, PMCA-type"
                     /protein_id="HBH0004668.1"
                     /translation="MEFNNDIKYYNVDKEEVTKDLSVNPEKGLSESEVKTRREKYGLN
                     EFTPKEEGSFWDDLKESLSEPMIVILIIAAVVSAVIGETHDAIGIVGAIAIGIAIGMI
                     TEGRSKKAAEALSKLTENIEVKVLRDGEVHQISKSELVPGDIVYIETGDMVPADGRLI
                     ESINLKIREDMLTGESDDVSKKCDVVVSMEEIESKGAVVVQEPIPAKQINMVFGGTLV
                     AYGRGALVVTSIGDNSEMGKIAQNLSETDEQTPLQIKLGNLGGLIAKVSSAVAGLLFI
                     FMVFQMISKNVLNVDMSGILPFLESIDPVKTAFTVCVALIVAAVPEGLPTMINMTLAI
                     TMQKMAKINALVTKKEACETIGSVSVICSDKTGTLTENRMTVEVAYVDGRYIESSEEE
                     INSYFEENCMINSTADVEHNDGDIKYLGSATECALLLYYKNVDYRQVRKNSNIVAQNP
                     FTSDSKRMTSVIGQDNHHVLLSKGAPEVLLELCSHIQRGKDIVPLTENIKHEILEEIK
                     KLQIKSMRTLGFAYKEISQAEEEAAVTAESDAMNVSAMENNLVFSGFVGIRDPLRKDV
                     IESVNTANKAGVSVKMLTGDNINTARAIGEELGLLKNNMRVVEASYIDTLDDEELKQE
                     IQSISIVARSKPDSKMRIVSALQKSGDVVAVTGDGINDAPALSKADVGIAMGISGTEV
                     SKNAADIILTDDSFSTIVKGIKWGRGIYDNFQRFVQFQLTVNVIAFLVAIISQVMGQE
                     MPFTTIQLLWVNIIMDGPPALALGLEPVRDHVLNRKPVDRKANIISKSMVYTIVLNAF
                     YITAILMLQSTFNFLGVDEAHKGTVMFALFAFSALFNAFNCREFNADSIFPNFTHNKL
                     ALQIIVLTGIAQVIFTQLFQDFFNSVAMDFMTWVKVLCVAASVIVVNEVVKCIIRLVK
                     PKKTA"
     gene            27052..28614
                     /locus_tag="KR231_002302"
     CDS             27052..28614
                     /locus_tag="KR231_002302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YceG family protein"
                     /protein_id="HBH0004669.1"
                     /translation="MGDSKVFEKIFSSQSDRGNYTPSKGYLSYFISYIGLEDEVLYNL
                     EIFKTKQNIDSKKDIALFTDVIANPSDFDIINYFKSGLQKYRTSMEDVDINILGFEEI
                     DYKIKQAMDRVLKEEEKEFTNDRVKQNFIVKIMAWIKIYIGALDINKNEAPKVIFYGD
                     IKKHEVYLLLILYLAGFDVLYLNPNSKSNIDILKSERYNIEFEEANIIEEKISFEERV
                     ILGEKIDKSSVKKAFTVGAEASKRISEELLNDAGFIKPWQLQDRKIKNLLLSSTVDEI
                     SIYWNQPLKLRPGFKFNDAIVEAPNFLSKINGIYNDKNEYIKFLDLLRDSESSTFIEF
                     NGDVDRFSKAFTREAFSLSFLLDSKGAIDKNSVLNNKDYSISTLALNQQIMILEKVEE
                     LLEGSMFLNGLSGEDKIKGLFTVLHMDKKFVHMMNNFDYSLINPKLIIYMYKSIVFDK
                     EIVFLMLLLSKIGFDIIILCPGGENNIENVINNQLIDVHRLDKMVYDLKLNSLENDIP
                     LLKKIFGKRRRF"
     gene            28615..29751
                     /locus_tag="KR231_002303"
     CDS             28615..29751
                     /locus_tag="KR231_002303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toxic anion resistance protein"
                     /protein_id="HBH0004670.1"
                     /translation="MGININSFSKDKNSVEVTENLPTAVQEENFDIMEYTNNKKNELR
                     KSKEVEALTSLIEVENPDTILQFGRKASEGVARVSDSLLNTIKLNRNEENSKMLVHLT
                     KIMDKFDLDDFQETKEPNFVQKLFKKANNAIEMMFQKYETLGGEVEKIQIELEQYERD
                     IALSNKQIGAMLNENFEFYNELQKYIVAGEMAIEEMDNEILPFFKQKSETSGDQMDVV
                     NYQELLKVYDMLNQRVYDLRIAENIAIQTIPMLRGMQHNNYGLIRKINSAFVVTLPVF
                     KQCLSQAILLKKQELQAKSLKALDDKTNELLLRNAQNVSTQSAQIARMAGTSSVQIET
                     LEKMYNTIKSGIDETMRIEENNRALIKDNTKRLEELNTTIIYNK"
     gene            29815..30891
                     /locus_tag="KR231_002304"
     CDS             29815..30891
                     /locus_tag="KR231_002304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HpcH/HpaI aldolase/citrate lyase family protein"
                     /protein_id="HBH0004671.1"
                     /translation="MKYFDYICKDDLERIFLKEPEDFSAKTEKDVLKYALGAFLYVPA
                     TQYNMIYKSIIGDVKGVRPLAICLEDAVGVNGELEAIENLRLILKNISNESITNKDGI
                     PLIFVRIKDVEQLLRIKEIIIKNRHSITGILIPKANSELIENCIEALDSMNLQDMYVI
                     PIIETKEFIYNEKKELSFTNLYNAILRHKSRILSIRVGITDILGMYGIRRDKNFSIYN
                     NLICSSFILDIITYLQRPELDIPISGGVSEFFDMTNKDIRNKYIEEILLDKYHGLIGK
                     TVIHPMQIQIVQALSTVSYEDFTDALDILDSTDSKYGVSKGVLGERMNETNPHFLWAK
                     KTLILSKIYGVLNKGVDYEELLKF"
     gene            30869..>31912
                     /locus_tag="KR231_002305"
     CDS             30869..>31912
                     /locus_tag="KR231_002305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosyltransferase family protein"
                     /protein_id="HBH0004672.1"
                     /translation="MKNCLNFNCEIDIIDNPLNLELNDFLDVGIRNNSKRRFLFISKK
                     LGKHLACKPSEMDNLGKLMATIYNEKNKEESNGTVIAFAETGTAVGHSFFDYLCGDYE
                     FIHTTREQFDELENLEFLEEHSHATDQNLYFGMLNNFKFGDEIILVDDEITTANTCMN
                     IIRKIQSIYPKKKYTICSILNWVSDENLSKVTRLERELDCKIDFVYLFKGNFKFYIDE
                     DIISNYNDNYSITKLETISSDKVNLVVNHIYVDLEDYIGNKKYVKYTGRFGINRREQF
                     RLKEIVKRESKKITMASKESLKNEKEKILFLGTEEFMYIPMLFAKEKENQYDIYYHST
                     TRSPIINIDKNNYP"
BASE COUNT        12341 a         3314 c         5607 g        10650 t
ORIGIN      
        1 ataaatttaa atatataaat gatttatttg gatatgaagt tgggaatgaa attttgcgta
       61 atttaacaaa gattattaag aggaatatat ttgaagagga aatgtttgca agaatatctg
      121 cggataattt tattataatt atgaaatata tagaagaaga agatataaca aagaggttaa
      181 aaactatatt tgaagaatta gacttgttta ataataatca agaagaaaaa tataagttag
      241 ttttaagttg tggaatctat tttatacttc cagaagatag agatatcaac tcaatcatag
      301 atagggctaa tatacctcat aaaatggcaa agggaggaca taaaagttca tatgcatttt
      361 atgataataa gattcatgac caagagataa aagaaaaaga gatggaaaat acaatgtttt
      421 caagtctaga aaataaagaa tttattatat acttacaacc taagatagaa cttaatacag
      481 gagagataca aggttcagaa gcacttgtta ggtggaaacg tcctgataaa gggctaatac
      541 ctccaaatga atttatccca ttttttgaaa gaaacggttt tgttataaat ttagatttat
      601 atgtgcttga agaagtatgt atatacctta gaaaatggat tgatgcagga ataaatccag
      661 ttactgtttc agttaatgtt tcaaggatac atttatattg caataatttt atagaaacat
      721 acaaaaatat aattgataaa tacaatatac ctgcaaagta tatagaactt gaattaacgg
      781 agagtatcat atttgataat tttgatattt taattgatat aatgaataat ttaaaaaaaa
      841 taggattttt aatatctatg gatgattttg gctcagggta ctcatcatta aatatgttaa
      901 aagaaattcc tatggatatc ttaaaacttg accaaaaatt tattatggaa acttataata
      961 gtaaaagaag caaaataatt gttactaaag taatagaaat ggcaaaagag ttgggtatga
     1021 aagtcatatc agaaggagtt gagacagaag aacagtttaa acttttaaaa gaagtaaagt
     1081 gtgatatggc acaaggatat ttgtttggaa agccaatgcc aattgaagaa tttgaacatt
     1141 taattgtatc taacttggta agagggtaat taatctgtaa tataaagaat ttaataaatt
     1201 gtgttaaaaa tggactctaa tgtagtgttc attttttttg taaaattttt tatactttta
     1261 ctaaaaagta attgacatat actttgtatt attatattat tgtattaaca acttaataca
     1321 ataatataat aaggaggcat gaacatggaa tgggaacttg ataataacaa acctatatat
     1381 atacaattag tagaacattt aaagttaaaa ataatttcag gggaaattaa aataggatct
     1441 aaattagaaa cagtgagagc actagcagaa gatgcggaag ttaatccaaa tacaatgcaa
     1501 aaggctctaa cagaacttga aagacaaggt ttagtttata gtcagagaac taaaggaaga
     1561 tttgtaacag atgataagga aaaaataaaa gctatgaaag aggaaatagc taatgtggag
     1621 ataaatacat taaaagtaac cttagaaaag cttggatatg atagagatga aatgctaaaa
     1681 cttattacag aaaatctgaa aggagaatta taaaatggat aaaaatataa gcaatgtttc
     1741 tcaagatgga atagttgaat ttaaaggtgt aaacaagagt tatggaacta agaatgtttt
     1801 aaaaaatatt gatttaaata taccaaaggg aaaaatagtc gggctgttag gacctaatgg
     1861 aagtggcaaa agtacaatga ttaagctaat gaatggatta ttacagcctg ataatggtga
     1921 aattatgata aatggaatga aaccatccat agatactaaa aaaatagttt catatttacc
     1981 agaaagaact tatttaaatg attggatgaa ggtatcagat ttacttaagt ttttctatga
     2041 tttttatagt gattttgatg ttagaagagc aaatgagatg attaaaagct tagatattga
     2101 tgtaaatgaa aagctaaaga caatgtctaa aggaactaaa gaaaaagttc aacttatttt
     2161 agtaatgtca agaaatgcga gcatatatat attggatgaa cctataggtg gtgttgaccc
     2221 agctgcaagg tcatatatac ttaagactat attaaaaaat tattctgaag atagtacttt
     2281 actgattgct acccatttaa taagtgaaat agaaaacata tgtgatgaga taatattcat
     2341 atcaaaagga gaaatagtgt tacaaggaga cgttgaagca ataagagaag aaaaaggaaa
     2401 atctatagat gcattattta gggaggaatt taaatgttag gtaaattatt aaaatatgag
     2461 ttaaaagcaa gtggaagaat atttataccg ttatatatag ccatattgat agtagctgta
     2521 tttaacggaa tatttatgaa tacaaatata cttcaggtac agggaatagg aatactagta
     2581 ttaacaagtc tttttatggc attaggagtt ttaactattg tagttacaat tcaaaggttt
     2641 agaaaaaatc ttttggggga tgaaggttat ttaatgttta ctcttcctgt tagcactagt
     2701 tcacttatat tatctaaatg tataacagca cttatatacg ctgtacttag ttttatagtt
     2761 gcagtattca cttttggagt tcttatgctt tttggtactt ctggaatttt actacctgaa
     2821 attttagatt tgtttaacac tagttttaaa tggatttctg aaaacttttt agatatttta
     2881 ttattagtag tagtaatgtt tatttcatat tcatcattta ttttgttatt atatacatca
     2941 atctcaatgg gacaattacc aaaattcaat aaacatagaa acatagtggc atttgcttct
     3001 tttatagcta taaatatagt aatatcaatt gttggagatg cagttggaag catcttacca
     3061 aatgaagata caaatatggt atatcatctt tatcagagtc ctagttttat gcttgcaata
     3121 cttggtagtc ttgtagttgc aatagcgtta tttttcgcta caaaatttat attagataaa
     3181 aaattaaatt tagaataaat gtttttatat ggagccatct tttgagtaat gttaaaagat
     3241 ggctcttatt atttatgtag ttaattcatg tatataatat gaatagtgtt ttatttctag
     3301 ttaaatatat acatatgttg tataatgata ttgcgtgtaa aaatttgtaa gaataactat
     3361 acactttata taagttatat caagaaaatt taaaaatata tggatttgag ggagaagata
     3421 tgaaaagtta tacaaaggct aagtggagtg tttggggtat aattacattt tcatttgttt
     3481 tagtattatt tttaaggatg tcaactgctg ttgtttcaga caatttagca aatgagttag
     3541 gttttaattc tatacaaatt tcaaatatag catccttttg cctatatgca tatgcattta
     3601 tgcaaatacc tgcaggaatt ttgattgata aatatggagc aagaaaaatt agcagtcttg
     3661 gaataataat ggcaagttta gggtcaattt tatttggttt gattcaaagt atagaattag
     3721 catatatttc tcgtgtaatt gtaggggcag gaacatcagt aatattactt tgtattttaa
     3781 aaattcaagg gagatggttt aataagtcag aatttgcttc tgcaacagct aaattttcat
     3841 ttgtaggaaa tttaggtgga gttcttgcta cttttccact tgtgtttttg tctgaacttg
     3901 ttggttggag aaattcattt ttattaatcg gtataattgg tgttgtaatt ggatgtttta
     3961 tgtatattat tgttagagat acaccaaaag agtatggatt caatatagat actgaaccct
     4021 atgaaaagtc agagaaggtt aatattgttg atggtattaa gtctgttata aagaacaaat
     4081 caacatggta taattcaatg ataatgttct cttttgtggg tcttacaagt gcatttataa
     4141 gcttgtgggg agtaagatac ataatggacg tttatggtgt gagtaagagt ttttctgcgt
     4201 ttatagtatc attttttaca tatggattta tatttggttc aataattatg gattttgtat
     4261 ttgctaaaat aaggtctagc aaatttaata taataaaatt tggggcaatg atagatttgt
     4321 ttatatggat tgtaattgta gttgtatacc aggtaaaacc accaattata gttttaccaa
     4381 tatcattctt tattatggga tgtatagtta tgtcacatct acaggttttt aatgatgcca
     4441 agtataaaaa taaagaaatt tattctggac tggcaactag tgttattaat acttttgaat
     4501 ttataggaag tggaattatt aatttgatta tagctatctc tttacaagta aattcatata
     4561 atatagttga tggatataaa aaaggttttg tagtatttat agtactaagt attataacta
     4621 tagtatcatc tcatataggg gtaaaaaatg atgattttaa ggctatatag tgttttatta
     4681 atagtttaat ttagtattat attttgcata tatatataac aaatagtttg cattttccta
     4741 agatgtataa ttggaatata aatcttgttt actatgtaca aatggtattg tattatatta
     4801 aatagaaaat aagaacttta aactataata ttggttctaa aatataaggt aaggagtttt
     4861 ttatggatac gacgaaaata gatgatataa gcaagttaga tttaaataat ttagatatta
     4921 ataagatgga tatgggaggt ataatggaaa gtctattaga atgggctact acaagcggag
     4981 taaaacttat aataggcata cttatacttt ctattggatt taaaataata aaaaaatttg
     5041 taaaccatgt tatgttatta cttagtaaaa gagatattga tttaacttta agaaggtttt
     5101 tgaagtctct tcttttgagt gtacttaaag ttgccgttat aatcattgtt ctggaatatt
     5161 ggggaatgag tttgtccagt tttgctgctg tgatagcatc agcaggggta gcaataggtt
     5221 tggctttaca aggtagtcta tcaaattttg ctggaggatt tattatacta ttgattagac
     5281 cttttaaagt aggagattac gtagaagcag caggccatgg aggaacggtt gaacaaatag
     5341 gactttttta tacacaattg gttactccag ataataaaca gatacttata cctaatggtt
     5401 ctgtatcaaa tgatagtcta ataaactatt cagcaaagaa tactagacga gttgatttga
     5461 cttttagtgt agggtatgaa gatgatatac tacatgttag aagagtactt aaagatattg
     5521 ttaataatca taaattaata ataaatgaac cagaaccatt tataggagta gtagaacatg
     5581 gagataatgc tattaaattt gcaactagag tttggtgcaa gacagaagat tattggacaa
     5641 tttatcttga tttactagaa gaggttaaag ttaggtttga cgaagaagga attacgattc
     5701 catatcctaa aatggattta acggtaaaag aattaaataa aatttaattt ttttatgtag
     5761 tgtttaaatt taagaatatt atatagatat atttataaga tttgtgaaaa attaataagt
     5821 cctgttattt tgtaagtgaa aatataaaaa atgggagtgt ctcaaaatga actttttagt
     5881 tcatgaggca ctctttttgt atgaaatcaa atatattttt attatttcaa caataaaaaa
     5941 gaggtctgtt tctattttga gacaatatta tttttatgta gatttaatct taatgagtat
     6001 aaagttttaa aactactaaa ataggaggaa ttttaatata aaagggtaaa taaagggttt
     6061 agagggcata atatagaata aattaattat ttaaggaggg tttttatgtg caaaaaaatg
     6121 tatttattag tggtaggtat acttatagca ggtttattaa ctgcatgtaa tgggagtcca
     6181 actaaggatt cagaacaagc acaagataat acaaaaaagg aggcaaatgt atcaaataac
     6241 gctttaaaag atgaaaaaaa taatgaaaat ttaatggaac aagattttaa agtgccatac
     6301 acagatgcaa taaacatatt taaagacaaa tacaaagatg ctgatatagt agatttaagt
     6361 cttgagagag atttaaataa atttgtttat actgtggaag gtgtagatga taataatgaa
     6421 tataagatga aaattgatgc taatacaaaa gatgtattag aagataaaac agaaaagttg
     6481 gattcagaag atttaaatgg agtcgctaga aaagaaaaat tagattttaa tgacataatg
     6541 acacctcaac aagctatgga aattgcatta aaagaacaaa atggaatggt taaagagtgg
     6601 agtttagata aagatttaga tgttactttt tataaaataa gaatagataa agataaaaat
     6661 gaatatgaca taaaagtaga ttctaaaaag ggaactgtat tgaaggtaga aaaagaagat
     6721 tagaagattt aaactatctt taaaataatt tcttttttga ataaaatttg tttaaaatat
     6781 aacaagtagg gtataaagag actaaataac tattttagga ggagtacggt atgtcattga
     6841 aatcgctaaa aataaaagaa aatttatatt gggtaggttc gcttgaccct gatttaagag
     6901 tatttgacat aattatgtat acaccttatg gaactactta taattcatat gtattaaaag
     6961 gaacagaaaa aacagtttta tttgagacag ttaaagataa gcattttgac aattatattg
     7021 aaagattaaa tgatttaaat atagattttg aaaaaataga ctatattgtt gtaagtcata
     7081 ctgaaccaga ccatgcagga agcgttgaaa agcttttgga tttagctaaa aatgcaaaag
     7141 tagtagcttc agaaacagca attaaatatc ttaaggaaat cgtaaacaaa gactttgaat
     7201 atgttgcagt tacagatgga gatacattat caattgggga caaaacttta gaatttttct
     7261 ctgtacctat gcttcattgg ccagatacca tatacacata tataaaagag gataaaactc
     7321 ttgtaacatg tgattcattt ggtagtcact atagtaatga taagatagta aatacacttg
     7381 atgaagatga agaaaaggat tacttggatg ctttgagata ctattatgat tgtataatgg
     7441 gaccatttaa accatctatg gtaactgcca tagaaaagat aaaagattta gatatagata
     7501 ctgtatgtcc aggtcatggt ccagtattaa ctgaaaatcc tagaaaaatt atagaccttt
     7561 attacaactg gagtgtaaat gaacaaataa agttagaaaa agaagttaca atttgttatg
     7621 tttctgcaca tggatataca aagattatgg cagaagctat aaaagcatat attgaaaaaa
     7681 atagcaacta taaagtaaat ttatttgatg taatagagca taagcaagaa gatattttgg
     7741 caaaaatagc agtatcacaa ggtgtattat ttggaacacc aacaatatta ggagatgcgt
     7801 taaagcctat atgggatata ttaatatcgt taaacccagt tcttcatggt ggaaaagttg
     7861 cttcagtatt tggttcatat ggatggagtg gagaaggtat agaaaatgct atggagagaa
     7921 taagtcagct tagaatgaca gcagtaaaac cttttgctgt taactttaaa ccatcaaatg
     7981 aagagattga taaattacat tcttatacag gtaaattcct agataagtta aattctactt
     8041 ttggaagtaa aaagaaaact aagaaattta aatgtgtaat ttgtaatgaa gtttttgaag
     8101 gtgatagtgc tcctagtgta tgccctgtat gtggagctaa ggaagaccaa tttatagaag
     8161 ttgaagaaga tgaagttact tttagaaaag atactgatga atatttcgta atagtaggaa
     8221 atggagcagc tggtttttat gcagcagatg ctataagaaa aagaaataaa acttgtaaga
     8281 taactatgat ttctaatgaa gatgagttga cttactatag acctgcactt tctgatggta
     8341 taaatgaaga acttggttca gatttctaca tggaagataa agattggtat gataaaaata
     8401 atatagtagt aatattagga acgaatgtag ataaattaga tgaagtgaat aaaactatta
     8461 tagtgaatga tggagctatt aaatttgata agcttgtaat agctacagga agtagaaact
     8521 ttataccacc aattaagggt catgatttag aaaatgtgtt tactcttaga aatataaaag
     8581 atttatatag tgtaaaagaa gcactagaaa aatctaagaa agttgtagtg attggtggcg
     8641 gtttattggg acttgaagct gcatgggaat ttagactaaa aggattagaa gtagtagtag
     8701 ttgaagccat ggatagcata ctatcaaaac aacttgataa agaaggcagt aaaatattag
     8761 aacaatgtgt aagagataca ggaatagatg taagattggg tgtagcagtt gatggtattg
     8821 aaggtgatgg aaaagctcaa aaagttgtat ttaaagatgg agatagtgtt gactgtgata
     8881 tggtagtatt ttcaattggt gtaagagcaa acactcaaat ggttcaggat acatctgtaa
     8941 aaattgacag aggtattgtt gtagataaga cattacagac aaatgttaaa gatatatatg
     9001 cttgtggaga tgttgcacaa gtgggaaata ttagtttagc aatatggcca tcttcagtag
     9061 aaatgggaaa aatagcaggg gcaaatgcaa gtggagataa tttgacattt gaaagtgaag
     9121 tatatccagt ttcattagat gcaatgaatg taaaagtatt tagtattggt aatatacaaa
     9181 attttgataa agaaatttca tcaaaagatg aaggtcaaag aatatataaa aaattattta
     9241 tgaaagatgg ttcattagtt ggagctatac ttataaatga tttaagctgt actgttaaat
     9301 tgataagatt aatatctgaa aaaggtgatt ttgaggatat tatgaaggct gatatactat
     9361 aatttaaata cattaaaata aaaaggagtt gtcttaaaat tgattttttt ctaatcaaat
     9421 tttaaattca actccttttt tgaattttta tataaaataa catggaaatt ttagtaatgt
     9481 ctgtggttac atacataggt ttaattgttt tttatatgga ttgtctctgg tataataaat
     9541 tgaattgtgt ttgactgata gatattttta ttgaaagtta atacctgtta tgcgataata
     9601 aggacgtgtt aggggagttt ttataataac aattaatctc agtttttgtg ttccaatagt
     9661 agcatcaaca cattctgatg tagtagttct tttcttataa aaattagtta caaatatgct
     9721 tgtaattatt tgatatgtaa atttaccaat attataaatg atgacctcga taataaggag
     9781 agtgaaaaat aatctatgaa cgaaaatatt ttgattgtgg atgatgaaaa agaaatagca
     9841 gatttaattg aagtatattt aaaaaatgaa ggttttacag tatacaagtt ttatacaggt
     9901 aaggaagctc tagaatgtat tgaatctaaa aatttggata tggctatttt agatattatg
     9961 cttcctgata ttgatggatt tcatatttgc cagaaaattc gagaaaaata ctattatcct
    10021 atcattatgt taacagctaa aattgaagat atagacaaga taatgggttt aaccataggt
    10081 gctgatgatt atataacaaa gccatttaac cctttggaag ttgttgcaag agtaaagaca
    10141 caattaagaa gatatatgcg atataataat tcttatgaac aacagtcgat aattgttaat
    10201 gagtatgata ttaaaggatt gattatcaat aaagaaacac ataaatgtag tttatttggg
    10261 aaagaagtag cattaacacc gattgaattt tctattcttt ggtatttatg tgaacatcaa
    10321 ggaaaagtgg ttccttctga agaattgttt gaagctgtat ggggagaaaa atatcttgat
    10381 aataataaca cagttatggc tcatataggg cgattacgtg aaaaaattca tgaaccttct
    10441 aaaaacccga aatttataaa aactgtatgg ggagtaggtt atacaattga aaagtaaaaa
    10501 tattaaagtc aatcctgact ttactcaagt gagaaataaa atttttatga gaacagcttt
    10561 aatggcattt atagccatta ttttcatatg gattttatat tcttttatat tgtatggtaa
    10621 gttttctatc tggatagtat cattctttga aaatgctttt cgtatggaat ataaagctgc
    10681 attgaattta tatcagcaga ttttccgtaa tagtatggag ctcttcatga tactagctat
    10741 ggtgattgtg ttttttataa tattccgtgt ttatttaaat tggtttacaa aatattttag
    10801 tgaaataaat caaggtattg actctcttat caaagaagat gttggagaag tggctttatc
    10861 tccagagtta ttggcaatag aaaagaaaat aaactcaatt aaacatatac ttgaacaacg
    10921 taaatttgag acacaaatgg cagaacaacg taagaatgaa cttattgttt atcttgcaca
    10981 tgatttaaaa acaccactta catcagttat agggtatctg acactacttc gagatgaaag
    11041 tcagatttct gaagaactgc gaaaaaaata tttatctatt tcgttggata aggcagagcg
    11101 tcttgaagat ttaattaatg aattctttga aattacaagg tttaatttat caaatatatc
    11161 acttgaatac agtacagtaa gcttaactcg tatgcttgaa caactaacat atgagtttaa
    11221 acctactttg atgagtaaga atttaaaata tacactgaat gttacaccaa atatgatgat
    11281 aaggtgtgat gttaataaaa tgcaacgtgt atttgataac ttattacgaa atgctgttta
    11341 ttatagtttt gaagatacta ctattgaaat aacagctgta caggaggatg attatataaa
    11401 gcttaaattt ataaatcata gcaatacgat tccagaggaa aaacttgagc gtatttttga
    11461 acaattttac aggttggata catctcgtaa ttcaaacagt ggtagagctg ggttgggact
    11521 tgctatagct aaagaaatag tggagcttca taacgggaca ataacagctc atagcgagaa
    11581 caatataatt acctttaagg ttattattcc gattgtagga aatttgtaag aatttaagta
    11641 taaaaaaata ggaaattctt taggataaat aaataaagag cactcttgtt attgatataa
    11701 ttactgtatc aaaacaagag tgcttttatt ttgatacagt aattatatca atagaaaaat
    11761 gtgaaaatat attatgtgga acagatgcaa ttgtaagtga aggttgattg gatttgaaat
    11821 agaaaaagta ttttaacatg tttctgtaga ttgtataaaa ataaataaat caacaaagga
    11881 gaatcaaaga tgaataataa aaaaattgca gttatatttg gtggaaactc aacagaatat
    11941 gatgtatcat tacaatcagc ttttgcagta cttgagaatt tgaatacgga aaaatatgat
    12001 attataccaa ttggaattac aagggagggt aattggtatc attatattgg agattataat
    12061 aatatccaga ataacacttg gtttgaaagg gatactgata taattccagt tattgtttcg
    12121 cagaaccgtg tcaaaaatgg tattattgaa tttttaattc ctgatgctgt ttctcagaat
    12181 catattccaa atagtgctat tgaatcatgt gaaaatgata ttaaatacac taaacttgat
    12241 tttgtgtttc ctgtactgca tggaaaaaat ggagaagatg gaacagtgca ggggttattt
    12301 gaattggcag gtatacaggt tattggatgt ggtactcttt cttcagcatt atgtatggac
    12361 aaagacaaat cacataaact tgttcattca gaaggtatta aagtaccaaa atcaatatta
    12421 ctaaaatact cagataaatt taatgtggct gaactgtcaa aagacttaac ttatccatta
    12481 tttataaaac ctgtgcgtgc aggttcatca tttggtatta gtaaaattta taaaaaagaa
    12541 gagttacaag tagcagtaga cttggctttt gaacatgata atgaagtaat aattgaggaa
    12601 aatattgatg gttttgaggt agggtgtgca gttttaggaa acaatgactt acttgttgga
    12661 agagtagatg aaatagaatt gtcaaaagga ttttttgatt atacagaaaa atatacattg
    12721 aaaagttcaa aaattcatat gccagctaga attgatttgg attgtgagaa aagaatacaa
    12781 gagacagcaa aaattattta tagaactctt ggatgttctg gatttgctag agtagatatg
    12841 tttttaactc catctggtga aattattttt aatgaagtca atacaattcc tggctttact
    12901 tctcatagtc gttatccaaa tatgatgaaa ggtattggac tgtcttttga agaaatattg
    12961 gacaagataa ttgaggtgta cataaaatga tgaataatat tttattagat aaaaataaag
    13021 aagataaaat gacaaatact atcttattga ctaaagataa agtttatgat gggaatctaa
    13081 ttctagtaaa tgctttttta ccagttaaaa catctgaaga tatagattta attcctgtag
    13141 atacaaggtt tccaagtatt cttatgaaac gtgaagctac aaacatttta caaaatattt
    13201 taaaaagtat atgtggaata aatgaaatag tacctgtaag tggatatcgt actgcagagg
    13261 aacaacaaga tatatattca agttctctgc gtgacaatgg aaaagacttt actaaaaagt
    13321 ttgtagcact tccaaatcac agtgaacatc agacagggct tgctattgat ttagggttaa
    13381 agaaagaagt tatagatttt atctgccctg aatttcctta taatggtatt tgtaatgagt
    13441 ttcgtaaggc agcactacat tatggtttta tagagcgtta tcagtgtaaa aaagaagaaa
    13501 taacaggaat atctcaagaa ccatggcatt ttcgttatgt gggatatccg cattctgaga
    13561 ttatcaataa aatgaatctc gctcttgaag aatatataga atatattaag agattttcgt
    13621 atacaaattg tttaaaaata gaagataaag aaaaaattat agaaatcttt tatgtgccta
    13681 ttcatactaa agaagaagtg agaatctcta tacctgaaca atgtgtatat caaatatcgg
    13741 gtaacaataa ggatggtttt attgtgacat tttggagaaa tagaaaggac taagaaatgg
    13801 aggaacaaga atgattagga ataaatctta tgcagggctt gattatttta ggattatagc
    13861 tgcattactt ataattgcaa ttcatacatc tccattatta tcatatagta aaatggctga
    13921 ctttgtgtta actagtataa ttgctcgtat tgctgtgcca ttctttttta tgctatcagg
    13981 cttttttcta atttcaacat ataattataa ttgtaataaa ctgaaatctt ttctaaaaaa
    14041 tgtattattt atttacggga tagctattgt aatttatatt cccttaaata tttacactgg
    14101 atatttttcc atgaataatt tagtgcccaa tattattaag gacattgtat ttgatgggac
    14161 tttatatcat ttatggtatc ttcctgcatc aattattggt gcaagtattg catactttct
    14221 tgtaaaaaaa ctaggtttaa agtactcact agtaatcact attgttattt atgtaattgg
    14281 tatgtttggt gatagttatt atggtttttt agaaaaaata ccactattaa agaatttata
    14341 tgggtatatt tttgaagtat cagattatac acgaaatggt atattttttg cacctgtatt
    14401 tttcatactt ggtggaataa tatctaataa atctaattat atgtcaacta aaaatagctt
    14461 gattggattt cttatatcat tcttacttat gttatgtgag ggaatgtttt tacataaact
    14521 aggggtacag cgtcatgata gcatgtatat tatgttattg ccatgtatgt atttcttatt
    14581 tacagcctta acatttttga aaggttctcg agctaggtta ttgcgaacat catcattaat
    14641 tatttatatt atacatccta tgatgattgt tgttattcgt atgttttcta aaatattcgg
    14701 aatacaaact gtcttggttg acaatagcct tattcattat atagtggtaa gtatagcatc
    14761 ttttatagct tctataatta ttatattgat tcttaaacct ctaaaaaaag acttgaaagg
    14821 agaacataag gtaaatacca atagagcttg gattgaaatt gatttaaata atttggaaca
    14881 taatgtaaag atgatacaaa aagctatgcc agaagattgt gaattgatgg cagttgtaaa
    14941 agctaatgcc tatggtcata gtgcttttga agtagcgact tgtgcaaacc aaataggtgt
    15001 aaaagcattt gcagtagcaa caatagatga ggggattgat ttacgtcgat atggaatact
    15061 aggagaaata ttgattcttg gatatactaa cccaataagg gcaaaggaac ttcataaata
    15121 caatcttaca cagagtgtta ttgaccttaa tcatgctatc tctttaaaca aacagaaata
    15181 caacataaaa tcacacatta aaattgatac aggtatgcac agactgggtt ttgatgttaa
    15241 tgatgtgagg tcaattttaa aggcatttaa attaaaatac ttagatatat gtggcatatt
    15301 tacacacttg tgtgtttcag atagtctgaa agatgaagat gtagacttta caaataaaca
    15361 aattgaatgt ttttataagt taattgattt tctgttaaaa aaaggtataa aaattcctaa
    15421 agtacatatt caaagtagtt atggtttttt taattatccc aatcttaagt gtaattatgt
    15481 aagaattgga attgcattat acgggatatt aagttttcca aatgatacga ctaaattgca
    15541 acttgattta cgacctgttt tatccttaaa atcacaagta attcttatta gaaaaataca
    15601 aaaagatgat agttttggat atggaagagt ctttattgca agcagagata gcgtaattgc
    15661 tatattatct attggctatg ccgatggtat acctagaaat ttatcctgtg gaaaaagtta
    15721 cgtaataata aatggttgta gagcagcaat agtgggtcga atttgcatgg accaacttgc
    15781 tgttgatatt acagatatac ctaatgtaga agttggtaat acggcaataa taataggaag
    15841 agataattta tctgaattat ctgtttctga agttgcaaat aactcatgta gtatatcgaa
    15901 tgaattattg agcagagtag gaagaaggtt aaatgttata aagaagtaac tcaattaaat
    15961 agtaatattt gttgtactgt gtaatttatt ttactctgac tagacatttt tagtaatatt
    16021 atgtctaata tatatttttt ataacttaca tgacaattta agttataaaa aggtgatgtt
    16081 tcagattttt attttgaaac atcacctttt ttgttataat atataataaa ataattatac
    16141 cttaactgta aacttatata gattatttac tttttaatat tagattcatt ttttgagatt
    16201 ggtatataat aaacatatag agtatataat aatagttaaa gttaaaaaag gggaaaagca
    16261 atatgcagta tatacaagaa ctacttgatt tgactcaaaa ttattgggtg ttagccacaa
    16321 taatcggctt attaagtgca tttatagaaa gctttatacc agccttacca cttgttgcta
    16381 tagttacagc aaatgctgca atacaaggat tatttattgg atgtttgtta tcatggattg
    16441 gctcaggact tgggacaact tcattattct tattaataag cagatttaat gatagtaagc
    16501 tttttaataa gttgagaaat agtaaaactg aaaaagcaat aagttggatg gataaacagg
    16561 gatttaagtt attatttata gcgtatgcct gtccatttat gcccggttgt ttagttacta
    16621 tcgcatcagc ttttggtaaa aaagatttaa aagattttgt gccagcaatg ttggcaggaa
    16681 aatttgtaat gtttatagtt ataagttacg tggcaagtga tatagaaggt tttataacaa
    16741 gtcctttaaa gatagcatca tttatattat tggtgttttt gtcatggaag attggaaata
    16801 gagtaaataa aaatcttgaa aatcataatt atgatttcca tcataaaaaa catcacaatg
    16861 ataaagatga taaaatgatt tagcttgtac gaaataaaac gtatcttaaa atgatttagt
    16921 actaaattat tttaagatac gttttatttt ttgtattaag gtacaaaatt tttagttctt
    16981 ttgtaaacta aaatatataa aacttattta tacttagttc aaaatattgt tatttatttt
    17041 ttctacaact ataataaaat ataaaattga tatccaatca aaaaaataac tatgaaattt
    17101 aatagcttag atatgaattt ttctgttttt gagttagttt ttataggtag taaagaaatg
    17161 tttatagtaa tgggataaaa caattcaata ccttctttag taataaggtc aagacacaag
    17221 tgagatagat atcctattat aaacccactg gacaaacatg agaaaactat attattgtta
    17281 gtgaagattg tcagagattt aaaaaaacta taaataagta ataaggcaat tagactgtga
    17341 gtaaaccctc tatgtctaaa cctacttcca aataatttgt atattaacat aaatttttta
    17401 cttatgtaag aacctctcat atctatatct ggaaataaag aacctaaata tgcaaaataa
    17461 atataaatta taattaatac tattttatat gcaatatcgt atttaactag gtacagattg
    17521 tttataaagg ggagtatcaa aagtgcgaat atataacctc ccctttcatg tgtttctttt
    17581 atcatataaa aatcctcctg aatcgtcact ataaacatta tattggtaaa tttagactat
    17641 cttttattat attatatagc aaacataagt ttttttcaaa aggattttaa tatttaatta
    17701 atcttgagat tttaaatttt tgtaattttc taaagcacca ttccaattta ctacattaaa
    17761 ccagttgtca atgtattcat ttcttctatt ttgatatttt aaatagtaag catgctccca
    17821 aacatcaagt cctattatag gagttaggtt tttacttaca gggctatcct gatttggagt
    17881 agtcataata gataatttcc catctttagt agctacaagc caagcccaac cagaaccaaa
    17941 gacatctaaa gcagattttt ggaactcttg cttaaatttt tcaaaagaac caaagtctct
    18001 atcaatagct tcttttaaag attcagaagg tatggttttt tctggcgtca ttatatcaaa
    18061 aaagaattta tgattataag ctccacctgc attatttctt acagttgtag caatatcttt
    18121 aggtaaagaa tctaaatttt gcaataattc acataaagaa taattataaa gctcaggata
    18181 tttttcaaga gcagcattta atttatcaac ataagcttga taatgcttat catgatgcag
    18241 tttcattgtt tctttatcta tataaggttc aagtgcatca tatgcataag gtaatggttt
    18301 aaccttaaat ttgttatttt caggtgtaaa agcaaatgaa gttatgcact gtgagattat
    18361 aaataaagac ataataactg gtattaatat ttttttcttc ataaaaatca cctcctaata
    18421 tagtatttct agaaataaaa aaaatatgaa atattaacag ataatttata agaatttaat
    18481 agcaatttca ttttaaattg aataagtttt aaagccaaag acaaaactat gaaatataga
    18541 ataagactaa aggacagaaa ggaattttga ttatatggac ggcaatattt caatttatta
    18601 taaaggtgat atatctaaaa aagaagatat taaatttaaa ataaaagaat ctgtaaataa
    18661 tacaagactt tctagtagaa tagagtataa ggatgaggaa aaaacttttg attttgaaag
    18721 atttaatgta attgatgcta tttatggaaa taaaccattt gaaaaagatg gaaaagttat
    18781 tgtttttaat ggaaatatat ataactatca tgaaataaaa gaagaattaa ttaaaaaagg
    18841 acacaatttt actacaaatg atgatattga agtcttattg gcatcttata tagaatttgg
    18901 taagaattgt gtacataaga ttaaaggaat gttcaacttt ataatctatg atagagaaaa
    18961 tgaaagtata tttggagcaa gagatttatt tgggataaaa ccactctatt atataaataa
    19021 ggaaaatgca ataatttttt cctcagagta taagttttta cttgaatata tgaaaaattt
    19081 aaatataaat gaaagaagct tacaaagtta tttttcattt caatatgtac ttcctgaaga
    19141 tactatgata caaggaataa ggctgatacc agcaggtcac tattttaggg tagaaaatgg
    19201 tatactatct ttaaagagat ataataaact tgagtttaga agtagtacaa aattttttta
    19261 tactaaaaat cacttaggca atagagatgt gaacgaggat gatataagaa atatagtagt
    19321 agattcaata gtaactcata tggaagagga gaaagaaatt ggaacatttc tgtctggtgg
    19381 aatagattca tctattataa ctactgtggc ttcacaaatt aatccaaata taaaatcttt
    19441 ttctgcaggc tttagtgtca aaggatatag tgaattagaa gtagcaaaga aaacagctga
    19501 taagttaggt atagaaaata tccagattaa tataacacaa gatgaatata taaaatcatt
    19561 accgaatgta atttattctt tggatgaccc tatagcagac ccttcagaag taggtcttta
    19621 tttcttaatt aaagaggcag gtaaacatgt taaagtagca ttgtctggag aaggagcaga
    19681 tgaattattt ggaggatata atatatataa agagtatagt actatgaaat cagttgtcaa
    19741 ttcacctact tatattaaaa gtatattagg aagagtttca gaacttatgc caaacataaa
    19801 aggaagaaat tatctttata gagctacaac accattagaa aaaagatata taggaaatgc
    19861 aaaagttttt gaaaacagcg aagtaaaaag attctttttt aagtataagg aaaagaatat
    19921 atatgaatac ctgttgtcta atttgtatag agatgcacaa aaaaataatt acgattatat
    19981 aagtaaaatg caacatatag atgtgaatac atggcttcaa ggcgatatac ttcaaaaaat
    20041 tagcaaactt tctacagctg agcaggttga acttagagta ccatttttat ataaagatgt
    20101 atttgatgta gcaaaaaatt taagaatgga gcaaaaaata aataagaata atacaaaagt
    20161 tttacttaga gaggcgttta gagaaatagt cccagaacat gttgttcaaa ggaaaaaatt
    20221 aggatttcca actccaataa gagtttggtt aaaagattct ctaggggata ttgtaaagga
    20281 aactatttat aattcaaatg tagatgaatt tatagataaa aaatatgcaa taaaactttt
    20341 agatacgcat cttaaaggtc atagagataa ttcgagaaaa atatggacta tatttacatt
    20401 ttgtctatgg catcaattat ttattgagca taaaaatgtc gagtattaat acttttttca
    20461 atattaatca gagggcaaaa gcatgcaatg ttttcaccct cctgattatt atggaatagg
    20521 ataagtagaa ttttgattga ttagtttact atctcaataa aattattggc aaatattttg
    20581 acaagattac tttcaacagc taaatttaag ttttgtccat catcatatcc agcggaaatc
    20641 aatcctagta agtttccaaa catatctaaa agagctcctc ctgaactacc actagagatt
    20701 ggagctgtaa attgtatcat ttgaaccgtt tcaaaatcac gaaaagctga aataattcca
    20761 tctgaaactg tattaaaaag acctagaggg cttccaattg caactatttt ttgacctctc
    20821 acaggttttt tactgacttt aacaggtatt ggcttgcatt ttctatcaac ctttatcaca
    20881 gctaaatcat aatctgaatg gtattttata atttggtaag atgtataaac tttatcatca
    20941 ttttcaaatc taactaaaaa tgaataccca tcattgacta catgaagatt cgtaagtata
    21001 taaccttcat tatttattac tactccagaa ccgctcttaa acggtttatt ttcgttattg
    21061 cacacaacaa tcataacaac agaagctgat aactttgcaa ggtcttcata agaaagttct
    21121 acttcctcat cttgtacaat ttttttagat gttagatttg tgttattaag tgtattttta
    21181 gagttaggtt tattcgtagt aggagaagtc ttattggtat tttcactgta atttatattt
    21241 gtaatatgcc tttcaaaagg tatttctaat atatttggag tcttcctaga aagttcaaat
    21301 agagtagaaa attttgaaca ttcaggatat aaatcaagaa tatctttatt tggatttata
    21361 tataaaatat cacacccaag ttgtgataaa aaatataaga aaaaaagttc ttgcctttta
    21421 atatttccaa agtatactat ctttggtgaa atagtagtct tcaccttgtt ataaaataat
    21481 ttaggtagaa aatagtctat ccaacacaaa agtttaactg caaagttttt gatgatagag
    21541 gatgtacaat ttggcatact tgtggaaaat aaatctaaag tatttttaaa tgcaatcttt
    21601 ttagtccaat ttaaggtgtc attttctatt ttacatggaa agtcgatatt atataaatcc
    21661 caactgttaa acttagaact attataaata ttaaaaattt taagcatctt atctgtttgt
    21721 tctttgtcaa aatttatttt tagattgttt aatctaatat agggaattgt aggattatta
    21781 aaaaaataag tatctatatt tttaattttt tctatgtatt tatcaattga atcatcaaca
    21841 cctatatatc ttgtaaagta gacttcttta atatatgaag aacgcttatt tttataggta
    21901 gtatcagata taaattcaat tagaggttca gtagactttt ttattgaaat ctttaatggt
    21961 ttaatagtac aaatcatatt ttttctccta taataagatg atataatcta ttataaaaca
    22021 acttaaaaca atatagtaca ataattttgt agtttcaaaa taaaatatgt acttgtttat
    22081 ataaatgata tataattaca tattaaacat agcttttatg catttaataa agtatgtaaa
    22141 atctatgtaa aaagtaagaa atataaacat ttttttaatt atattttaaa aatatcaagc
    22201 aagttttatt cacaaatgaa taaaaaatgt tataatatga ttaaagaaaa agataaataa
    22261 ttagcaagat ttgtttagct aaaattaaca agggagcgat aaattatggg tataacatta
    22321 tcaaaaggcc aaaaggttga tttaactaaa ggaaatccag gtcttaaaaa tattttagta
    22381 ggtttaggat gggatactaa caagtatgat ggtggatttg actttgattt agatacagca
    22441 gcatttttaa caggagcaag tggaagtgtt actaatgatg gagattttgt attttacaac
    22501 aatttaaaac atacatctgg agcagttgag catctaggag ataacagaac tggcgaaggt
    22561 gatggagatg atgaacaaat agttgttgat ttatctaaga ttcctggaga aataagcaag
    22621 atttctttta ctgttacaat tcatgatgca acagaaagaa gacaaaattt tggacaagta
    22681 agtaattctt atataagaat agtagataaa gacacaaatg aagagttaat aaagtatgaa
    22741 ttaggagaag attttagtat agaaacagct atagtagtag ctgaaatata taagcacaat
    22801 ggagaatgga agtttaatgc actaggttct ggctttgaag gtggtcttgc tgcattatgt
    22861 ggaaactttg gaataaactt ataatttcaa ctataacaat aaactaaagg gggatatttt
    22921 ccatggctat agtattaaaa aaaggacaaa aaatcgattt aactaaggga aatccaggtc
    22981 ttaaaaatat aaaacttgga ctaggatggg atacaaattc atttgatagt ggctatgatt
    23041 atgatttaga tgtaagtgtt ttcatggttg gagaatctca aagagttgaa aaagatgaag
    23101 attttatatt ctacaataac ttaaaacatc catctggagc agttgaacac ttaggtgata
    23161 atagaactgg tgaaggtgat ggagatgatg aggaaatatt agtgaattta gagacaatgc
    23221 caaagcatat acaaaagata gctgtaacag ttacaatata tgaggctgct gaaagaagac
    23281 aaaattttgg acaagtaagc aactcatata taagagtatt aaattctgaa aatgatgaag
    23341 aaatattaag atatgactta ggtgaagaat ttagtataga aactgcaatt acagtatgtg
    23401 agatatataa gtataatgga gaatggaagt ttagtgcagt tggagcagga tttgaaggtg
    23461 gcttagaagc actttgtaga aactatggct taaatgttta atttaagcaa tataatatat
    23521 taaatataaa taacctatac aaataatgta taggttatat tatataaaat tttgtggagg
    23581 tttagtatgt cgattaattt atcaaaaggt gataaaatag atttaaaaaa atctaaccca
    23641 ggactgagta acatacttgt aggtctagga tgggaccctg tgcaacaatc tggcggaggt
    23701 ttttttaaat cgttatttgg tggaggacaa gctgatatag attgtgatgc atctgtattt
    23761 atgcttaatc aagaaggtaa attaagtgga ataaaagatt taatttattt tggaaatcta
    23821 aaaagtgcct gtaaatcagt tttgcataca ggagacaatc taactggtga gggtacaggt
    23881 gatgatgaac aaatcctagt taatttggat aaagttccat caaatattca taaattattg
    23941 tttgtagtaa atatatacaa ttgtgtagat agaaaacaac actttggaat gatagaaaat
    24001 gcctatataa gagttgaaga ccaaggtaat aagaaagaga tagcaaaata caatctatct
    24061 gataattatt ctgaaaaaac tactcttata gtaggagcta tatatagaaa agatggaagt
    24121 tggcaattta aagcaattgg tgaaggaaca aaagatgcgg gtcttaaaga agtaatgcaa
    24181 aatttagaaa ggattgagtg tgcatatgga atttaataat gatatcaaat attataatgt
    24241 agataaagaa gaagttacaa aagacttatc tgttaatcct gaaaaaggtt tatcagaatc
    24301 agaagtcaag actagaagag aaaaatatgg tttgaatgaa tttactccaa aagaagaggg
    24361 tagtttttgg gatgatttaa aggaaagttt aagtgaacca atgatagtta tcttgattat
    24421 tgcagcagta gtaagtgcag taattgggga aactcatgat gcaataggga ttgtaggtgc
    24481 tatagcaata ggtatagcaa taggtatgat tacagaaggt cgttctaaga aagcagcaga
    24541 ggctctttct aagttgactg aaaacataga agtaaaagta ttgagagatg gggaagtaca
    24601 tcaaatttct aagagtgaat tggtaccagg tgatatagta tatattgaaa ctggtgacat
    24661 ggtacctgct gatggtagac ttatagaaag tataaacctt aaaattagag aagatatgtt
    24721 aacaggagaa tctgatgacg tatctaaaaa gtgtgatgta gtagtttcta tggaagagat
    24781 agaatctaaa ggagcagtag tagtacagga accaatacct gcaaaacaga taaatatggt
    24841 gtttggtggt acacttgtag cttatggtag aggagctcta gttgtaactt caattggaga
    24901 taatagtgaa atgggtaaaa ttgctcaaaa cttatcagaa acagatgagc aaactccact
    24961 tcagataaaa cttggaaatt taggtggttt gatagccaaa gtttctagtg cagtagcagg
    25021 attactattt atatttatgg ttttccaaat gataagtaag aatgtattaa atgtagatat
    25081 gtctggaata ttaccgtttt tagaatcaat agacccagtt aaaacagcat ttacagtatg
    25141 tgttgcgttg atagttgcag cagtgccaga aggtcttcca actatgataa atatgacact
    25201 tgcaataaca atgcaaaaaa tggctaaaat aaatgcattg gttaccaaaa aagaagcttg
    25261 tgaaacgata ggttctgttt ctgtaatatg ttcagataaa actggtacat taactgaaaa
    25321 tagaatgact gtagaagttg catatgttga tggcagatat attgaaagtt cagaagagga
    25381 aataaatagt tattttgaag aaaactgtat gataaactct acagctgatg tagagcacaa
    25441 tgatggtgat attaagtatt taggaagtgc tactgaatgt gcattgcttt tatattacaa
    25501 aaacgtagat tatagacaag ttagaaaaaa ttctaatata gtagctcaaa atccttttac
    25561 ttcagattca aagagaatga cttctgttat aggtcaagat aatcatcatg tactattatc
    25621 aaaaggagca ccagaagtct tacttgaatt atgttcacat attcaaagag gaaaagacat
    25681 agttccatta actgaaaata taaaacatga gattttagaa gaaataaaga aattgcaaat
    25741 aaaatcaatg agaactttag ggtttgcata taaagaaatc tcacaagctg aagaagaagc
    25801 agcagtaact gctgaaagtg atgctatgaa tgtaagtgca atggaaaaca atttagtatt
    25861 tagtggtttt gttggtataa gagacccact tagaaaagat gttatagagt ctgtaaatac
    25921 agcaaataaa gctggtgttt ctgtaaaaat gcttacagga gataatataa atacggcaag
    25981 agctataggt gaagagttag gcctattaaa aaataatatg agagtggttg aagcttcata
    26041 tatagatact ttagatgatg aagaattaaa acaagagata caaagtattt caatcgtggc
    26101 aagaagtaaa ccagatagta aaatgagaat agtttcagct ctgcaaaaga gcggagatgt
    26161 tgttgcagta acaggtgatg gtataaatga tgctccagca ctttcaaaag cagatgttgg
    26221 tatagcaatg ggtatatctg gtacagaggt atctaaaaac gcagcagaca taattttaac
    26281 tgatgatagt tttagtacca ttgtaaaagg tattaaatgg ggtagaggaa tttatgataa
    26341 cttccaaaga ttcgttcaat tccaattaac tgtaaatgta attgcatttt tagtggctat
    26401 aatatctcaa gttatgggac aagagatgcc atttactaca atacaattat tatgggtaaa
    26461 catcattatg gatggaccac cagcactagc attaggttta gagccagtta gggaccatgt
    26521 gttaaacaga aaacctgttg atagaaaagc caatataatt tctaagtcaa tggtgtatac
    26581 aatagtatta aatgcatttt atataacagc aatactaatg ttacaatcta catttaattt
    26641 cttaggagtt gatgaagcgc ataagggaac agtaatgttt gcgttatttg cttttagtgc
    26701 actgtttaat gcatttaact gtagagagtt taatgcagat agtatcttcc ctaattttac
    26761 acataacaaa ttagcactac aaataatagt gttgacagga attgcacaag taatatttac
    26821 tcagctattc caagatttct ttaactctgt agcaatggat tttatgacat gggtaaaagt
    26881 tttatgtgta gcagcaagtg taattgtggt taatgaagtt gtaaaatgta taataagact
    26941 ggtaaaacca aaaaagactg cttaaaacaa attttttaga agaaaacaga ctgactcaaa
    27001 atatgaattt tgggtcagtt ctgaataaac atttaaattg ggaggatagt tatgggtgac
    27061 tcaaaggtat ttgaaaaaat attctccagc caatcagata gaggaaatta cactccttca
    27121 aagggatatc taagttattt tatttcgtat attggtttag aagatgaagt tttgtacaat
    27181 ctcgagatat ttaaaacaaa acaaaatatt gatagcaaaa aagatattgc tttatttact
    27241 gatgttatag caaatcctag tgattttgat attataaatt attttaaaag tggacttcaa
    27301 aaatatagaa ctagcatgga agatgtagat ataaatattt tgggatttga agagattgat
    27361 tataaaataa agcaagcaat ggatagagtg ttaaaagaag aggaaaaaga atttactaat
    27421 gatagagtta aacaaaattt tatagtgaaa ataatggcat ggataaaaat ttatatcggt
    27481 gctttagata taaataaaaa tgaagctcca aaagtaatat tttatggaga tataaaaaaa
    27541 catgaagttt atttactctt aatattatac ttggcaggtt ttgatgtttt atatcttaat
    27601 ccaaattcaa agagtaatat agatatttta aaatcagaaa gatacaatat agagtttgaa
    27661 gaagccaaca taatagaaga aaaaatttct tttgaagaaa gggttatttt aggggaaaaa
    27721 atagataaaa gttctgtaaa aaaagctttt actgttgggg cagaagcatc aaagcgtata
    27781 agtgaggaat tgttaaatga tgcaggattt ataaaacctt ggcaactcca agatagaaaa
    27841 ataaaaaatc tacttctaag ttcaactgtt gatgaaatat caatatactg gaatcaacca
    27901 cttaaattaa gaccaggatt taagtttaat gatgctattg tagaagctcc aaattttctt
    27961 tctaagatta atggaatata taacgataag aatgaatata ttaagttttt agatttatta
    28021 agagattcgg aaagttcaac atttattgaa tttaatggag atgtagatag attttcaaaa
    28081 gcttttacaa gagaagcttt tagtttatcc tttttattgg attcaaaagg tgcaatagat
    28141 aaaaactctg ttttaaataa taaagattat tccatatcaa cattagcatt gaatcaacaa
    28201 attatgattt tagagaaagt ggaagagttg ttagaaggaa gtatgttttt gaatggttta
    28261 agtggagaag acaagataaa aggtctattt acagtacttc acatggataa gaaatttgtt
    28321 catatgatga acaatttcga ttactcactt ataaacccaa aattgattat atacatgtac
    28381 aagagtattg tatttgataa agaaatagtt tttcttatgc ttttacttag taagattgga
    28441 tttgatatta tcatattatg tccaggagga gaaaacaata tagagaatgt tataaataac
    28501 caattgattg atgtacacag attggataaa atggtatatg accttaaatt aaattcgctt
    28561 gaaaatgata tacctttact taaaaaaatt tttggaaaga ggagacgatt ttagatgggg
    28621 ataaatataa atagtttttc aaaagataag aactctgtag aggttactga gaatttgcct
    28681 acagcagttc aagaagaaaa cttcgatata atggaatata caaataataa aaaaaatgaa
    28741 ctgagaaagt ctaaggaagt tgaggcattg acatctctta tagaagtaga aaatccagat
    28801 acgattttac agtttggtag gaaagcatct gaaggagtag caagagtttc tgatagcctt
    28861 ttaaatacaa taaaattaaa tagaaatgaa gaaaattcta aaatgctggt tcatttaact
    28921 aaaataatgg acaagtttga tttagacgat tttcaagaaa ctaaggaacc aaatttcgtt
    28981 caaaaacttt tcaaaaaagc taataatgcc attgaaatga tgtttcaaaa gtatgaaaca
    29041 ttgggaggag aagttgagaa aattcaaatt gagcttgaac aatacgaaag agatatagca
    29101 ctttctaata agcaaatagg tgctatgtta aatgaaaact ttgagtttta caatgaactt
    29161 caaaaatata ttgttgctgg agaaatggca atagaagaaa tggataatga aatactacct
    29221 ttctttaaac aaaaatcaga gactagtgga gaccaaatgg atgttgtcaa ttatcaagaa
    29281 ctattaaaag tttatgatat gttaaatcaa agagtctatg atttaaggat agcagaaaat
    29341 atagctatcc aaacaatacc tatgcttaga ggtatgcaac ataataatta tggtttaatt
    29401 agaaaaataa atagtgcatt tgtcgtaact ttaccagtat ttaaacaatg tttatctcaa
    29461 gctatattac ttaaaaagca agaattacaa gcaaaatctc taaaagcact tgatgacaaa
    29521 actaatgaat tattgcttag aaatgcacaa aatgtaagta ctcaaagtgc acaaatagct
    29581 agaatggctg gaacaagttc tgttcaaata gaaacattgg aaaaaatgta caatactatt
    29641 aaatctggta tagatgaaac tatgagaata gaagaaaaca atagagcttt aattaaggat
    29701 aatacaaaga gattggaaga attaaatacg actataattt ataataagta gtattatatt
    29761 aagggctaat ttgtataaag ttggcccttt ctatgtatat gaggaggcta gacattgaaa
    29821 tatttcgatt atatctgcaa agatgatttg gagagaattt ttttgaagga gccagaagat
    29881 tttagtgcta agactgaaaa agatgtgttg aaatatgcac tgggcgcttt tttatacgtt
    29941 ccagctactc aatataatat gatttataag agtattatag gggatgttaa gggagttaga
    30001 ccattagcta tttgtttaga agatgctgtt ggagtaaatg gagagttaga ggctatagaa
    30061 aatcttagat taattttaaa aaatattagc aatgaaagta taactaataa agatggaata
    30121 ccactaattt ttgtaagaat aaaagatgtg gagcaactgt tgagaattaa agagattata
    30181 attaaaaata gacattctat aacaggaata ttaattccta aagcaaattc ggagttaata
    30241 gaaaattgta tagaagcttt agattctatg aatcttcaag atatgtatgt tattccgata
    30301 atagagacaa aagaatttat atataatgaa aaaaaagaac ttagttttac taatttgtac
    30361 aatgctattt taagacataa gtcaagaata ttaagcatta gagtaggcat aactgatata
    30421 ttagggatgt atggtataag gagagataag aacttctcta tatataataa tttgatttgt
    30481 tcttcattta tattagatat aatcacatat cttcaaagac cagagttaga tatacctata
    30541 agtggtggag tatcagaatt ttttgatatg acgaataagg atataagaaa taagtatata
    30601 gaagaaatat tattggataa atatcatgga ttaattggaa agaccgtaat tcatccaatg
    30661 caaattcaaa ttgtacaagc gctatctaca gtatcatatg aagattttac tgatgctttg
    30721 gatatactgg atagtacaga cagtaagtat ggtgtgagca agggtgtatt aggagagaga
    30781 atgaatgaaa caaatccaca ttttttatgg gctaaaaaaa cattgattct atctaaaata
    30841 tatggtgtat taaataaagg agtagactat gaagaattgc ttaaatttta attgtgagat
    30901 tgacattatt gataatccat tgaatttaga actaaatgat tttttagacg taggaataag
    30961 aaataatagc aaaagacgtt ttttgtttat ctcaaagaaa ctcggtaaac atttagcatg
    31021 taagccaagt gagatggata atttgggaaa attaatggct acaatttata atgaaaaaaa
    31081 taaggaagaa tcaaatggta ctgttatagc ttttgctgaa actggtacag ctgttgggca
    31141 tagttttttt gattacttat gtggagatta tgaatttatt catactacta gagagcagtt
    31201 tgacgagtta gaaaatctgg aatttttaga ggaacattcc catgcaacag accagaattt
    31261 atactttggt atgcttaaca actttaaatt tggagatgag ataatattgg ttgatgatga
    31321 gattaccaca gccaatacat gcatgaatat aattaggaaa attcaaagca tttatcctaa
    31381 aaagaaatac actatatgct caatactcaa ttgggtaagt gatgaaaatt taagtaaagt
    31441 tactcgttta gaaagagagc tagattgtaa gatagatttt gtatacttat ttaaaggaaa
    31501 ctttaaattt tatatagatg aagatattat ttcaaattac aacgataatt atagtattac
    31561 taaattagag actatttcaa gtgataaagt aaatttagta gtaaatcata tttatgttga
    31621 tttagaagat tatattggaa ataagaaata tgtaaaatat acaggaagat ttggaattaa
    31681 tagaagagaa caatttagat taaaagaaat cgttaagaga gaaagtaaaa aaataactat
    31741 ggccagtaaa gaatctttaa aaaatgaaaa agaaaagatt ctatttttag gtactgaaga
    31801 atttatgtat atacctatgc tgtttgcaaa agaaaaagaa aatcaatatg atatatacta
    31861 tcattcaaca acaagaagtc caattattaa tattgataag aataattatc ct
//
LOCUS       DAEPHU010000048        31488 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 01A10CD0081
            SAMN05941466-rid12468953.denovo.048, whole genome shotgun sequence.
ACCESSION   DAEPHU010000048 DAEPHU010000000
VERSION     DAEPHU010000048.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941466
            Sequence Read Archive: SRR6291087
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 31488)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 31488)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068158.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 22:43:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,892
            CDSs (total)                      :: 3,805
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 87
            rRNAs                             :: 8, 1, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 55
            CDSs (without protein)            :: 55
            Pseudo Genes (ambiguous residues) :: 0 of 55
            Pseudo Genes (frameshifted)       :: 21 of 55
            Pseudo Genes (incomplete)         :: 28 of 55
            Pseudo Genes (internal stop)      :: 16 of 55
            Pseudo Genes (multiple problems)  :: 8 of 55
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..31488
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941466-rid12468953.denovo.048"
                     /strain="01A10CD0081"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            302..502
                     /locus_tag="KR231_002306"
     CDS             302..502
                     /locus_tag="KR231_002306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000809131.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HBH0004673.1"
                     /translation="MKNGIVKWFNNEKGFGFISVEGEDDVFVHFSAIQNDGYKTLEEG
                     EKVSFDITQGNRGPQAENVNRI"
     gene            complement(668..1546)
                     /gene="speB"
                     /locus_tag="KR231_002307"
     CDS             complement(668..1546)
                     /gene="speB"
                     /locus_tag="KR231_002307"
                     /EC_number="3.5.3.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="agmatinase"
                     /protein_id="HBH0004674.1"
                     /translation="MKNNFYHMNTFMSMNKNYEESNLIVFGVGFDGTTSNRPGARFAS
                     SSMRKEFYGLETYSPFLDLDLEDYNICDYGDLEISVGSTEQVLKEIYQETYKIVRDSK
                     VPFMIGGEHLVTLPAFKAVHEKYNDIYVIHFDAHTDLREEYNNSKNSHATVIKRIWDI
                     VGDNKIFQFGIRSGTKEEFKFATEEKHTYMEIGGIDTFENIVNMLNGKNIYLTIDLDV
                     LDASVFPGTGTPEPGGVNYREFQEIFKIIKNSNINIVGCDIVELSPDYDTTGVSTVIA
                     CKILRELCLIISDKIK"
     gene            complement(1536..2387)
                     /gene="speE"
                     /locus_tag="KR231_002308"
     CDS             complement(1536..2387)
                     /gene="speE"
                     /locus_tag="KR231_002308"
                     /EC_number="2.5.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyamine aminopropyltransferase"
                     /protein_id="HBH0004675.1"
                     /translation="MELWYTEEWTENVRFSIKVNKHLFEGKSQFQRIDVFDSDEFGKF
                     LTIDGLMMVTYKDEFIYHEMITHVPMATNLNIKKVLVIGGGDGGTVRELSRYPQIEKI
                     DMVEIDKMVVDVSKEYMDICSCKLDDKRVSLYFEDGVNFVKCAHDKSYDLIIVDSTDP
                     IGPGEGLFSTDFYKDCYRILTDDGILVNQSESPYFDFNAKEMKRANKKLKQIFPISEV
                     YQAHIPTYPSGHWLFGFASKKLNPVKNQDRNGWEKLSLKTKYYNSDIHLGSFMLPQYV
                     KEMLDEE"
     gene            complement(2417..2830)
                     /gene="speD"
                     /locus_tag="KR231_002309"
     CDS             complement(2417..2830)
                     /gene="speD"
                     /locus_tag="KR231_002309"
                     /EC_number="4.1.1.50"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenosylmethionine decarboxylase"
                     /protein_id="HBH0004676.1"
                     /translation="MKFETLGRHILVEYYNCDENVLKDPRLIENFMNDSALNAKATIV
                     DSVFHHFNPWGVSGAVIIAESHLTIHTWPEYGYAAADFFTCGDIDPWKSFELLEQLLK
                     SERSESTEIPRGLTTKIKKYSKKDLGKITHKPEAV"
     gene            complement(2917..4392)
                     /locus_tag="KR231_002310"
     CDS             complement(2917..4392)
                     /locus_tag="KR231_002310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class V-fold PLP-dependent
                     enzyme"
                     /protein_id="HBH0004677.1"
                     /translation="MDSEFANAVELSYECAPLLESLKEYSEKDIACFDVPGHVKNRGV
                     AILNKYLGESLMKMDINSSPTMDNVSAPNGIIKNAQDLLAQAYMADEAFFITNGTTQA
                     IHAMILSVIKPGEKVLLPRNIHKSVINALILCGGIPIFIQPEFDEKLGISLNITLEKV
                     RTEIEKDCNIKALFFLNPTYYGVCADLESIIELCHKNNVLVLVDEAHGAHFPFHLDLP
                     PSAISLGADMVAVSIHKTGGALTQSSALLLNRDNVSFEKVLQSINMLQSTSASYLLMA
                     SIDGARVNLVENGEKQLSKALNLSRYAKSKLNKIDGIKVLSTEILKQKGVKFIDETKL
                     CINVKELNLTGFEVYDLLYKNFSIQVELGDSYNILALVSIGTNKSDIDRLVKALSIIA
                     KIYRKESTLNEFNMVQINPIIKLNPREAFYAPKESVEINSCIDRICGESIMAYPPGIP
                     IIAPGELITEEIMEYIIFLKNSNAYLTDVQDKNLDRILVIK"
     gene            complement(5030..5683)
                     /locus_tag="KR231_002311"
     CDS             complement(5030..5683)
                     /locus_tag="KR231_002311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBH0004678.1"
                     /translation="MKVDPLTTQVYDYISKKIQNGEYEANQRITESEICKSIGVSRTP
                     AREALTRLAGENLLEKIPNKGFVVKEFQEKEKLDTYSVIGVLDALAGSSALQNLTESD
                     LVKMEELTEMMAVSIKYKNYNSYLKLSNEFHDIYITKSDNQVLVNLLNSLRYNFMSKS
                     YTSDNEDELYKMLTYSNNQHIEVVKSMRENDLENVERILREHWKTIPIAEMKKEKLL"
     gene            complement(5928..7793)
                     /locus_tag="KR231_002312"
     CDS             complement(5928..7793)
                     /locus_tag="KR231_002312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 13 protein"
                     /protein_id="HBH0004679.1"
                     /translation="MQSVIEYNSWDKNFKAPFGALKFDEELTICVKVNEGYNIKSISL
                     EINREEEMRTITLNEELDNDKLGKCFCGKIEKFDGTGVYFYYFKVDVEMDGQIKTLFY
                     GKNRDNGYSCEYNYSDINKYQITVYKDFKVPTWYKEGILYHIFVDRFNNGNRSGKVDN
                     PKKNSFIYGNWEDTPMYIKDSQGDVIRWDFHGGNLRGIINKLGYLKKLGVSILYLSPI
                     FEASSNHKYDTGDYKKIDPMFGDEDTFKELIDKAKEKGISIVLDGVFSHTGADSKYFN
                     MYGNYNSLGAYQSKESPYYSWYMFEEFPQKYKSWWDVKTLPNINELEHSYMDYIIYDN
                     DSVINKWVNMGIKGWRLDVADELPTKFIRELKKELKKADDDSILIGEVWEDASNKISY
                     GQRRSYLLGEELDSVMGYPFRNNMFSFLKGEINSYELCNRYMQIKENYPKESFRSNLN
                     LIGTHDVTRAKTELNDDVDLVKLAVAIQMTFEGVPYIYYGDEAGLCGGVDPDNRRTYP
                     WKNEDEDMLNFYRDVIKIRNKNKLLSSGNTEFIYTNNDSVFSFIRVNENNDRMLILVN
                     RSENVESISLCIESSFIEEIPIKYSLKNANSTIQIENNELKVDLDSKSFRIFRVN"
     gene            complement(7798..10218)
                     /locus_tag="KR231_002313"
     CDS             complement(7798..10218)
                     /locus_tag="KR231_002313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycogen/starch/alpha-glucan phosphorylase"
                     /protein_id="HBH0004680.1"
                     /translation="MVTISKKKFKQKFEVKMYSLYAQSIKEATDEQLLNVLCSLLKDE
                     IAKKWVATKLDKKKEVYYFSLEFLIGRQLKSNLLNLNIEEEVREGLSELGINLDDLIE
                     TEVDPALGNGGLGRLAACFLDSMASLNISGQGYGIRYKYGLFEQKFVNGYQVEVPDNW
                     LTEGRYAWETVRPNEATMVKFGGEVELIKEGSHLKVIHKNYLPVMAMPYDIPIIGYQN
                     QCINTLRLFKSEIPKRDFGELTSNALNYSGSYEEALKHKYYTEEISQVLYPDDSNYAG
                     KLLRLKQEYFFVSAGIQDIIRKYKKNKLNINNLFDKVAIHINDTHPTLCIPELMRILL
                     DEENLSWDEAWEITKKTVSYTNHTIMSEAMEKWPVSMMKELLPRIYMIIEEINRRYVE
                     ELNNKGYDQDRIKRMSIIDCDNINMANLCIVTSHSVNGVAKLHTHILETEVLKDFYQD
                     EPNKFNNKTNGIAHRRWLISSNPQLSNLITDLIGDSWKKDTLQLKNIEKFKNDSSVLQ
                     RLDDIKYNNKANLAKFIKDKYDLNVDPSSIFDVQVKRLHAYKRQLLNIFNVLHMYHEL
                     LDNPNLNLDPRTFIFGAKAAPGYYLAKCIIKFINSVASTINNDVRVKDKLKVVFLENY
                     GVSLAEIIIPAANVSEQISTTTKEASGTSNMKFMMNGAITLATLDGANVEICEQVGKE
                     NMFLFGLSAEQVLNYNKYGGYSSLDLYHSNMDIKRVVDDLINGFIPNLGEEGRSIYNS
                     LTTYNDEYFVLRDFENYGQAQADINRLYRDKEKWNKMSLVNIANSGFFSSDRTISEYA
                     KDIWFKRV"
     gene            complement(10232..11674)
                     /gene="glgA"
                     /locus_tag="KR231_002314"
     CDS             complement(10232..11674)
                     /gene="glgA"
                     /locus_tag="KR231_002314"
                     /EC_number="2.4.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011053260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycogen synthase GlgA"
                     /protein_id="HBH0004681.1"
                     /translation="MKVFYVTAECWPFAKTGGLGDVSYALPKELKKEGVDVRVIMPKY
                     STIPSYLKDQLKEIAVFSVRVGWRNQYCGLLEMELDGVKFYFIDNEFYFRREDERKSI
                     YGYGDDAERYTFFTDAVLEAISRIDFYPDVIHINDWHTGMLPLILKERYATLEGYKNI
                     KTMYTIHNLQYQGVFDKHVLYDILDLPQKYFDNGDIEYYGSINFMKAGINFADKIITV
                     SPTYANEIQTSFYGEQLDGLLRKESGKLKGILNGIDYDLNDPAKDKDIFVHYDVDSID
                     KKVENKLRLQDILGLKKDSSIPLIGIVSRLVSQKGFDLIAYMMPELMREDLQIVVLGT
                     GEHQYQSMFNYYDSNFSDKVSARITFNASLAQQIYAASDMFLMPSLFEPCGIGQMLAM
                     RYGSLPIVRETGGLRDTVTPYNKFTGEGNGFSFKNYNAHEMFFCLKNAIKVFKDKEKW
                     IKLVENAMKTDNSWKKSAKEYIETYRDICD"
     gene            complement(11703..12833)
                     /gene="glgD"
                     /locus_tag="KR231_002315"
     CDS             complement(11703..12833)
                     /gene="glgD"
                     /locus_tag="KR231_002315"
                     /EC_number="2.7.7.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate adenylyltransferase subunit
                     GlgD"
                     /protein_id="HBH0004682.1"
                     /translation="MRNECLGIINLNKKGDPAINKLNYGRPIASTPIAGRYRIIDFAL
                     SNMINSGITKVGIFAKEKYRSLTDHIGSGKDWDLSRKKGGLSIFSPENTKYRNTYSHR
                     EGDIYTILANLDYIEKSEEEYILIAPSYMLCNLNYSQALEYHKKSHNDITIIYKNVNN
                     ANKDFAGNLTLNLDSNNRVINVGNNLGKFPRANICMETYIMKREDFVECIYNIVNKGN
                     YCYLEEFIIEEAENMKIGAYEYTGYLKCVNSVESYFEMSKDLLNLEVADELLYSERKI
                     FTKEKNESPTIYTDSAKVENSFIASGCLIEGTVKDSIIFRKVNVEKGTVIENSIVMQN
                     CVIKSNAKLYNAILDKNTSVSNGKELRGDEKYPLVVEKNTNI"
     gene            complement(12835..13995)
                     /locus_tag="KR231_002316"
     CDS             complement(12835..13995)
                     /locus_tag="KR231_002316"
                     /EC_number="2.7.7.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate adenylyltransferase"
                     /protein_id="HBH0004683.1"
                     /translation="MKKEMLAMILAGGQGSRLGVFTKRIAKPAVSFGGKYRIIDFVLS
                     NCSNSGIDTVGVLTQYRPLILNSHIGMGSHWDLDRINGGVYVLQPFMNEKEGNWYNGT
                     AHAIYQNMDFVDTYNPEYVLILSGDHIYKMDYSKMLKFHKEKGSKATIAVIEVPWDEA
                     SRFGIMNTNEDSSIYEFEEKPSEPKSNLASMGVYIFDWKMLRNYFKEAEKNPEINYDD
                     FGKNLIPKMLEDNVGMYAYPFKGYWRDVGTIQSLWDANMDIIKSPETLDLADPKWKIY
                     TNTMAMPPQYIGKNANVHRSMIADGCRILGEVGNSVLSHGVVVGKGSKVIDSVIMPNV
                     VIGENVTIEKAMIGECATINDNVQIKNVNNEINVVSEYENIEPRCVLIEGGL"
     gene            complement(14766..15809)
                     /locus_tag="KR231_002317"
     CDS             complement(14766..15809)
                     /locus_tag="KR231_002317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH/Band 7/PHB domain protein"
                     /protein_id="HBH0004684.1"
                     /translation="MGTKIVLSIVLIVVVVAISLTCIRVIKQSKVGIIMRLGKFQKVA
                     ETGVHFLIPFLDKMAYVIDLREIVIDFPPQPVITKDNVTMQIDTVVYYKVTDPVRYVF
                     EIANPIAAIENLTATTLRNIIGELDLDETLTSRDIINVKMRTILDEATDKWGIKVNRV
                     ELKNIMPPQDIQVAMEKQMRAERERREAILQAEGNKSAAILQAEGEKQSAILTAEAKK
                     EAMVRVAEGEKESAILVAEGEAEAIRQTAIAKAQGEAEMIKRTQMATAEGLKLVFSAM
                     KEADIDNNILALKSMEALEKMAEGKSTKLVLPSEAVNFLGTFKGIKEVMSDDNKEVLD
                     IKEVLNDNESLKK"
     gene            complement(15830..16276)
                     /locus_tag="KR231_002318"
     CDS             complement(15830..16276)
                     /locus_tag="KR231_002318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NfeD family protein"
                     /protein_id="HBH0004685.1"
                     /translation="MKLIWLIVAVLFGIAEMLTPSLTLIWFSVGAVILIFLSSFIESI
                     FLQILIFAVISIAMLVVATKKIVKKDKGYKSNTNLQAMMSKKGIVTEEISPNNTGLVV
                     VEHETWTAISIDGEKIEKGSTVEVLKIEGVKLVVKKVDATVNVTNQ"
     gene            complement(16458..18038)
                     /locus_tag="KR231_002319"
     CDS             complement(16458..18038)
                     /locus_tag="KR231_002319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional ADP-dependent NAD(P)H-hydrate
                     dehydratase/NAD(P)H-hydrate epimerase"
                     /protein_id="HBH0004686.1"
                     /translation="MLIGTSKLSRNVDTACVEEVGIPMIVLMENAVISAMKNMDIDMY
                     NSYTVVCGVGNNGGDGLGIARHLNTYGKEVNVFLVGNLEKLSECSKINYNVLLNMGIN
                     IININKNDLSEKNYGEENEVDKIIKVEKQNIIKNKNLTIFKDRVSKSDVVVDAIFGTG
                     LKRDITGIFKEVIDIVNDNSKNTYSIDIPSGIDSDNGNVLGTCIRANKTISFEFYKRG
                     FLNYDTSALIGDVVVEKIGVPDFITRKYHDEEFITDKTFVKNNIRRRDKHGFKSDFGK
                     VSIVAGSKGFYGASFIATESAVKSGSGLVTLISSEDVQEKVSIRLTEAMTLNFEEERL
                     NKLLNSSDAIGFGPGMGDNSQTFDKLLKIVENSNCPIVLDADGLNVMKDRCYKFLEWK
                     NRFVITPHLGEMARLTGDSIGYIREHRVDVAKEFAQKYNLVVLLKGYQTVITDGKKTY
                     INPTGNSCMATGGMGDCLLGMITSFIGQGMDILEATVSGAYIHGYIGDKLSKAMYTVN
                     ATDLISNISLTMKELLDI"
     gene            18837..19739
                     /locus_tag="KR231_002320"
     CDS             18837..19739
                     /locus_tag="KR231_002320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905178.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBH0004687.1"
                     /translation="MSGIISVMTQSLILSIMALGVYITYKILDFPDMSADGSYTMGAS
                     IVAFSLTNGISPVVATLMAILCGCTAGLVTGILHIKFKISNLLSGILVMGMLYSINLR
                     IMGKSNIPLFSFKHLFNGEISPIVLALAFVFICKVLLDLFLKTGLGYTLKGVGDNSQM
                     IKSLGINIGSIKILGLMISNGLIALSGSLMAQFLGFSDVNMGIGTLVLGIASIIIGIT
                     LFKKFTFIKDTTAIIVGSFIYQFTIYFAMSLGMLSTDLKLITAIVIIAFLATGNLNIS
                     LKKNKCKASTKNKSEKRGVVDVTN"
     gene            19726..20481
                     /locus_tag="KR231_002321"
     CDS             19726..20481
                     /locus_tag="KR231_002321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003399531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBH0004688.1"
                     /translation="MLQIKNLSKSFPNPYGEPNTIFENLSIDIEDGEFVSIIGSNGTG
                     KSTLLNIISGLIKESSGQITLDSTTITNLAEYKRTQIVSRVFQDPSLGTCPSMTVREN
                     LSLALNKGKLLNLKKCLRHKTNDLEHLLEGISLDLKKYLDIKVQYLSGGQRQSLSLIM
                     SSLASPKVLLLDEHTAALDPKTSNEVIELTDKIVREKNITTLMVTHNLKHALQYGDRL
                     IMLHKGEVVLDVKDKEKKDLTVEEILEKFEYAV"
     gene            20578..21615
                     /locus_tag="KR231_002322"
     CDS             20578..21615
                     /locus_tag="KR231_002322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HBH0004689.1"
                     /translation="MIKSKKILSLIIAGVLGVSMLTGCSQNDGSNASNENKETDSKKQ
                     KNIGITQLVEHPSLDKAKKGFIKALEDKGYKDGDNIKIDFQNAQNDMPTTQSIASKFV
                     SDKKDLIYAISTPSAQAAYNATKDIPIIMTAVTDPVEAGLVKSLEKPGGNVSGTSDYL
                     SIDKTLELVKTLTPKAKKIGVIYNTSEVNSKIQVDSLHDYAKKNNYEVVEKGISSSSE
                     VNQAISSLVGKIDVLYVPTDNLIVSSMPIVSKVANENKIPIIASEEGSVSSGALACCG
                     IDYEKLGYKAGELAIEVLEGKSVGDIPVTTLDETEIIINEDTLKALDMQKLSADNIKY
                     IKSDENAKSTK"
     gene            22424..23326
                     /locus_tag="KR231_002323"
     CDS             22424..23326
                     /locus_tag="KR231_002323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905178.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBH0004690.1"
                     /translation="MSGIISVMTQSLILSIMALGVYITYKILDFPDMSADGSYTMGAS
                     IVAFSLTNGISPVVATLMAILCGCTAGLVTGILHIKFKISNLLSGILVMGMLYSINLR
                     IMGKSNIPLFSFKHLFNGEISPIVLALAFVFICKVLLDLFLKTGLGYTLKGVGDNSQM
                     IKSLGINIGSIKILGLMISNGLIALSGSLMAQFLGFSDVNMGIGTLVLGIASIIIGIT
                     LFKKFTFIKDTTAIIVGSFIYQFTIYFAMSLGMLSTDLKLITAIVIISFLATGNLNIS
                     LKKNKCKASTKNKSEKRGVVDVTN"
     gene            23313..24068
                     /locus_tag="KR231_002324"
     CDS             23313..24068
                     /locus_tag="KR231_002324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBH0004691.1"
                     /translation="MLQIKNLSKSFPNPYGEPNTIFENLSIDIEDGEFVSIIGSNGTG
                     KSTLLNIISGLIKESSGQVLLNKHNLSNLAEHRRTQIVSRVFQDPSLGTCPSMTVREN
                     LSLALNKGKLLNLRKCLRYKRDFLENLLEGVSLDLKKYLDVQVKFLSGGQRQSLSLIM
                     SCLTNPSVLLLDEHTAALDPKTSNEVIELTNKIVREKNITTLMVTHNLKHALHYGDRL
                     IMLHKGEVVLDVKGKEKEQLTVEEILEKFEYAV"
     gene            24199..25221
                     /locus_tag="KR231_002325"
     CDS             24199..25221
                     /locus_tag="KR231_002325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437194.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HBH0004692.1"
                     /translation="MINKKRLASLILAGALSISMLTGCSQGGDSGNSKQESNSKGKEV
                     KKIGITQLVEHPALDATRTGFVKALEKNGFKDGENIDIDFQNAQNDMPTTQSIASKFA
                     SDKKDLIFAISTPSAQAAFNATKDIPILITAVSDPVAAGLVKTLEKPGTNVSGTSDFV
                     SVDKGLELLKIFAPKAKTIGVMYNTSEVNSKVQVDALKEYASKNGFKVVEKGITTSNE
                     VNQGISSLVGKIDVLYVPTDNLVASSMPIVSKIATENKIPVIAAESGPVEKGALACQG
                     INYEKLGYKTGEMAVKILNGESVSDMPVATSDDTDIIVNEDILKALGMEKPSNENISY
                     VKTKQE"
     gene            complement(25385..25942)
                     /locus_tag="KR231_002326"
     CDS             complement(25385..25942)
                     /locus_tag="KR231_002326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar O-acetyltransferase"
                     /protein_id="HBH0004693.1"
                     /translation="MTEKEKMLSGKGYYANDELLVKEREYCKKLTRLFNNTLEDEYEK
                     REDILRQLFGSVGKQINVEQNIRCDYGYNIHVGENFFANYDCIFLDVCKIEIGDNVML
                     APNVQIYTAYHPIDAQLRNSGIEYGSPVKIGDNVWIGGGVIITPGITIGDNVVIGAGS
                     VVTKDIPPNTVAVGNPCRVIKKIEE"
     gene            complement(25948..27024)
                     /locus_tag="KR231_002327"
     CDS             complement(25948..27024)
                     /locus_tag="KR231_002327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfate/molybdate ABC transporter ATP-binding
                     protein"
                     /protein_id="HBH0004694.1"
                     /translation="MSLYVDIEKDLSSFKLKVEIKQEKGTLGFLGESGSGKSMTLKCI
                     AGLEKPTRGKIVLNDRVLFDSEKKINLSTQDRKVGFLFQNYALFPHMTVSQNIELGLL
                     KLSKSEKKEIVARYLDILKLNGFEGRYPWQLSGGQQQRVALARALATSPDILLLDEPF
                     SALDHHLRSNMEKELMNMLKDYKGDILFVTHDIEEAYRVCDDIIVYNKGEGLPKRPKK
                     ELFESPKYLIEAKITGCKNISKLNRLDKNTIYATDWGCELTLNREIGDNIEYVGIREH
                     HIKVLDSNEDLNEKLCFELINIVENPFTYTIYVRKTDLSNECVPIQIELEKSKMRFKK
                     GDRIYLDFPQEYLFCFRYNYNKKE"
     gene            complement(27025..27708)
                     /gene="modB"
                     /locus_tag="KR231_002328"
     CDS             complement(27025..27708)
                     /gene="modB"
                     /locus_tag="KR231_002328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdate ABC transporter permease subunit"
                     /protein_id="HBH0004695.1"
                     /translation="MGTDWSPLWISLKTSILSTIITFVIGIFVSYIMANYRGKWKGLI
                     DGLFTLPLILPPTVVGFFLLLLCGKNGFIGKFLLNFDRTLIFSWTATVISAVVVSFPM
                     MYRTSRSAFEQIDNNMLSAARTLGLNEWKVFFKIAVPLAWPGIIGGLVLSFARALGEF
                     GATLMIAGNIPGKTQTMPIAIFFAVEGGDMNKAMMWVMIIVAISIAMILLLNYWSEFQ
                     QKIIGKRCG"
     gene            complement(27857..28669)
                     /gene="modA"
                     /locus_tag="KR231_002329"
     CDS             complement(27857..28669)
                     /gene="modA"
                     /locus_tag="KR231_002329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdate ABC transporter substrate-binding
                     protein"
                     /protein_id="HBH0004696.1"
                     /translation="MKKILGILGLVACLTLGTVGCNSNEDKKDDGKQEKTTKSSDSVE
                     LNISAAASLKEAMAKIEEEYKKVDSNVKLTVNYGASGSLQQQIEQGAPCDLFISAGQK
                     QMKALDEEKLLVSDTMKDLVKNDLVLISSADSSVSGMEDLTTDKVKKIAVGEAESVPA
                     GKYADEVLTNLNLKDKLKDKLVFAKDVKEVLAWVQSGNADVGFVYFSDTVNNDKIKVV
                     EKTDEKTHSPITYPVSVIKASKNVDAAKKFEEFLLSESGQKIFEEFGYKKVE"
     gene            28862..29791
                     /locus_tag="KR231_002330"
     CDS             28862..29791
                     /locus_tag="KR231_002330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBH0004697.1"
                     /translation="MDSLSSLTPVEVAELLKITKNTVYELIKRGELPSYKVGKKIRVD
                     TKDVEEYINSQKTGKVKDTHFNNKNIDINNNFKIIISGQDVILDILARSVEKKLDGIS
                     TFRSYIGSYNALYELYNGRVSIASSHLWDFETDEYNSTFVKKLLPGIPCVLINLAYRM
                     QGFYVAKGNPKEITTWEDLTKPSITIVNREKGSGTRVLLDGKLRLLNFNGKHIKGYDN
                     EELSHLGVASTVSRGIADVGLGNEKAALQVNNIDFIPLHKERYDLVIKKEDLQNPVYQ
                     TIINIINSPEFKAELQGLGGYDLTDTGKTIAKV"
     gene            complement(29952..30401)
                     /locus_tag="KR231_002331"
     CDS             complement(29952..30401)
                     /locus_tag="KR231_002331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0004698.1"
                     /translation="MKNKNNKDKNMLNIKVLRVLGVLLILFDYTGDTLNFYNFFAKPL
                     VSGNLYKTTGTDCIVFLLFIVECVYLVGRYILKVKINWSEIIENEKGNFINNLLVEKI
                     QEESNIVYNLLNSYVLPNIYKKARGLMFKTYHMLIYIKEKYYYVNIY"
     gene            complement(30604..>31488)
                     /locus_tag="KR231_002332"
     CDS             complement(30604..>31488)
                     /locus_tag="KR231_002332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HBH0004699.1"
                     /translation="FGKLVYNSSVGLEQLIKNEDIVKIFSERKDKPLEKLKNYKTSEL
                     MIQSSNNYKLESLFITSNIKTRDTMILVHGIGSSYYEMLKVAYRYLDKGYNVLVYNQR
                     NTGNSGGDNYTFGLYERYDLDSLVKFVKNKFPEGRLGVHGFSMGAGTAAMHSEINSKD
                     DKVDFYILDSPYSEMKDAIRMGVLEKRIPDILINYVVTCGDLYNKFKSGFWYSDVKPY
                     ESVEKSNVPILFIHGTKDTVCNYQNSKKMYDLVKHDKKDLWLIEGIGHVDGFEHDSTV
                     YFNKIFKFIDSNVLSDKS"
BASE COUNT        10470 a         5245 c         3536 g        12237 t
ORIGIN      
        1 ctatttttat ttttactttt caatctaata tataatattt tttattatat attttaattt
       61 tactttttac ttacatacct ttttgttaca ttttttgata ttaaatttat tatctacatt
      121 tacattttcg tcaaatttta caatacttct cactgtataa tttaacaatt tttattaaat
      181 tctaaaagta attaattttt ttaaaaattt tatttgcttt tatttaaaat ttatgttata
      241 ttaatagaac agacttattt ttttagtttg tattttttaa taatgcggag gttttcttat
      301 aatgaaaaac ggaatagtaa aatggtttaa caatgaaaaa ggatttggat tcatatctgt
      361 agagggagaa gatgatgttt tcgtacattt ctcagctata caaaatgatg gatacaaaac
      421 tttagaagaa ggcgaaaagg ttagctttga tataactcaa ggtaatagag gacctcaagc
      481 tgaaaacgta aatagaatat aattatttaa tttaaatata tatattttag aaaaggagct
      541 atcgagggct cttttttgtt gtttattata tttattttta attacaaaaa taagaagtta
      601 ctttagaaaa gcgtcaaact taaaataact tcttatatta taatatatac tatttatata
      661 aaatactcta tttaatttta tcagatatta ttaagcataa ctctcttaag attttacaag
      721 ctataactgt cgatacacct gttgtatcgt aatcagggct taactctaca atgtcacaac
      781 caactatatt tatattagag ttttttataa tcttaaaaat ctcttgaaac tctctataat
      841 ttacaccacc aggttctggt gtacctgttc ctggaaacac agatgcatcc aatacatcta
      901 aatctatagt tagataaata ttctttccat ttagcatatt aactatattt tcaaacgtat
      961 ctattcctcc tatttccatg tatgtgtgtt tttcttctgt agcaaattta aattcttctt
     1021 ttgtcccaga ccttatacca aattgaaata ttttattatc acctacaata tcccatattc
     1081 ttttaattac tgttgcatga gaatttttac tattattata ttcttccctc aaatcagtat
     1141 gggcatcaaa atgaattaca tatatatcat tatacttttc atgtactgct ttaaaggctg
     1201 gtaatgtaac taaatgctct cctccaatca taaagggtac ctttgaatct ctaacaatct
     1261 tatatgtctc ttgatagatt tcttttaaga cttgttctgt acttccaaca ctaatttcta
     1321 aatctccata atcacatata ttataatcct ctaaatccaa atctaaaaaa ggactatatg
     1381 tctcaagacc gtaaaattct tttctcatag agctacttgc aaatctagcc ccaggtctgt
     1441 tagaagtagt tccatcaaat ccaacaccaa atactataag attagattct tcataatttt
     1501 tgttcatact cataaaagtg ttcatatgat agaaattatt cttcatccag catctccttc
     1561 acgtattgag gtaacataaa cgaacctaaa tgtatatcac tattataata tttagttttt
     1621 aaacttaatt tctcccatcc atttctatct tgatttttta ctggattaag tttttttgaa
     1681 gcaaatccaa acaaccagtg accagatgga tatgttggta tatgtgcttg ataaacttct
     1741 gatattggaa atatctgttt taacttttta ttagctcttt tcatctcttt agcattaaag
     1801 tcaaaatacg gactttcact ttgatttact aaaattccat catcagtcag tattctataa
     1861 caatccttat aaaaatcagt tgagaaaagc ccttcacctg gtcctattgg gtcagttgaa
     1921 tctactatta tcaggtcata tgatttatca tgtgcacact taacaaaatt aacaccatct
     1981 tcaaaatata aactcactct tttatcatct aatttacatg agcatatatc catatactct
     2041 ttagatacat ctacaaccat tttatctatt tcaaccatgt caatcttttc tatttgagga
     2101 taacggctta attctcttac tgtacctcca tcacctccac ctatgactaa tactttcttt
     2161 atgtttaaat ttgtagccat aggaacatga gttatcatct catggtatat aaattcatct
     2221 ttatatgtta ccatcattaa tccatctatt gttagaaatt ttccaaattc atcactatca
     2281 aacacatcta tcctttgaaa ttgagacttt ccttcaaata gatgtttatt tacttttata
     2341 gaaaatctta cattttctgt ccattcttct gtataccaaa gttccatata ataatcctca
     2401 ctttctcttg tatgttttat actgcttctg gtttatgagt aatcttacct aaatcttttt
     2461 ttgaatattt tttaattttt gtagttaagc ctcttggaat ttctgtagac tcgcttcttt
     2521 cagactttaa aagttgctct aataattcaa aacttttcca tgggtctata tcaccacaag
     2581 taaaaaaatc tgctgctgca taaccatatt caggccatgt atgtattgtc aaatgagatt
     2641 cagcaattat aacagctcct gaaacccccc aaggattaaa atggtggaat acagaatcca
     2701 caattgtcgc ttttgcattt aatgctgaat cattcataaa attttctata agacgtgggt
     2761 ctttaagtac gttttcatca caattatagt attctactag tatatgtctt cctagtgttt
     2821 caaatttcat ttcaacccca actcctttat acttttaata agttctattt gataaactct
     2881 acttaacaaa cacttgccct tgcaaaataa agtaatttat tttattacta gtattctatc
     2941 taagttttta tcttgtacat ctgtaagata tgcattgcta ttttttaaga aaataatata
     3001 ctccataatt tcttctgtta tcaattctcc tggagcaata atcggtatac ctggtggata
     3061 tgccattatt gattctccac aaattctatc tatacatgaa ttgatttcta cactttcctt
     3121 tggtgcataa aaagcttctc ttggattaag tttaataatt ggatttattt gaaccatatt
     3181 aaattcattt aatgttgatt cttttctata aatctttgca attatagaaa gtgcctttac
     3241 taatctatct atatctgatt tatttgttcc aatggacaca agtgccagta tattatatga
     3301 atctcccaat tctacttgaa ttgaaaaatt tttatataat aaatcgtata cttcaaatcc
     3361 agtcaaattt aattctttta catttataca caattttgtt tcatctataa atttaacacc
     3421 tttttgtttc aatatttctg tagataaaac ttttattcca tcaattttgt tcaatttaga
     3481 ttttgcatac ctagatagat ttaatgcttt tgacaattgc ttttcaccat tctcaactag
     3541 attaactcta gcaccatcta tacttgccat aagcaaataa gatgctgatg ttgattgtag
     3601 catattgatt gattgaagaa ccttttcaaa acttacatta tctctattca ataagagtgc
     3661 tgaagattgt gtcaatgctc ctccagtttt atgtatactt acagctacca tgtcagctcc
     3721 caaacttatt gcagaaggag gtaaatctaa atgaaatgga aaatgtgcac catgagcttc
     3781 atcaactaac actaaaacat tatttttatg gcatagttct ataatactct caaggtctgc
     3841 acaaactcca tagtaagttg gattaaggaa aaataatgct tttatattac aatctttttc
     3901 tatctctgtt ctaacttttt caagagtaat atttaaactt atacctagtt tttcatcaaa
     3961 ttctggttgt ataaatattg gtattcctcc acaaagtatt aacgcattta ttactgattt
     4021 atgtatgttt cttggaagta atactttttc acctggtttt ataacactca aaatcattgc
     4081 atgtattgct tgagttgtgc cattcgttat aaagaatgcc tcatcagcca tatatgcttg
     4141 tgctaacaaa tcttgtgcat tttttataat cccatttggc gcagatacat tatccatagt
     4201 tggtgatgaa tttatatcca ttttcatgag actttcacct agatatttat ttaatatagc
     4261 tacacctcta ttttttacat gtccaggcac atcaaaacaa gctatatctt tctctgagta
     4321 ttcctttaac gactctaata atggagcaca ctcatagctt aattcaactg catttgcaaa
     4381 ctcgctatcc atgatttcaa attcatctcc tctctatatt caaatatttt taatatttat
     4441 tatttattat ttctattttt tatttttact tttattaaac tcatgatatt tattatatta
     4501 acatcccagc atttttacaa gtgttttttt gaagttactc aaaaacatat acattagcta
     4561 tatcaatatt tataaacttt ttaatttttt gttgtttata ttaatttttt taaaacttag
     4621 tatttataaa ctttcttatt ttttattatt ttggtttttt tacttttttg agttttagta
     4681 agcttttgag tttactattt ttaatttata agtattttat tactaaactt ttatattatt
     4741 cttatttcac atatcaaaat tcttggttta gttggactaa ataattttcc tatttttgta
     4801 ttttaatttt aatataaaat ttattaaatt ttttaattga taaaataaat tctatattta
     4861 tgatattaaa attctataag ttcattgatt tatatatgtt aatttaaata cattattcta
     4921 tcgtagtgcc ttagagtttt tatttgtatt taaagttaaa tttattcttg tttttccttt
     4981 aatatttaat agtaaaacaa caaaattata aaaaaaataa agagaaactt tataaaagct
     5041 tctctttttt catctctgct ataggtatcg ttttccaatg ttctctcaaa attctttcaa
     5101 cattttctaa atcattctcc ctcatagatt ttactacttc aatatgttga ttattgctgt
     5161 atgtcaacat tttatataac tcatcttcat tatcactagt atatgacttt gacataaaat
     5221 tatatcttaa agagttcaat agatttacta acacctgatt atctgattta gttatgtata
     5281 tatcgtgaaa ttcattactt aattttaaat agctattgta atttttatac tttatagaga
     5341 ccgccatcat ttctgttaat tcttccattt ttactaggtc tgattcagtt aaattttgta
     5401 atgctgaaga accggctaac gcatccaata ctccaattac ggaataggtg tctaatttct
     5461 ccttttcctg aaattctttt actacaaatc ccttattagg tattttttct agtaaatttt
     5521 cacctgctaa cctagttaat gcttctctcg ctggtgttct actaactccg atagatttac
     5581 aaatctcaga ttcagtaatt ctctgattag cttcatattc tccattttgg attttctttg
     5641 atatatagtc atatacttga gttgtaagtg gatctacctt cataagacgt tcctccatat
     5701 taagattata aaagttaaat ctccctacaa ctttggtaga gagttcagtt ttatcttact
     5761 aatttatata atatcacaat tatgatattt tttatacttc tttgtaatat tttgaaatac
     5821 taaaattctt atgataattt atacaaaaaa agtagaaaaa gttttgataa aacaaaactc
     5881 tttccacatt cgccttattt tctatttatt tttctaaaaa aagatattta atttactcta
     5941 aaaattctaa atgatttaga gtctaaatct actttcaact cattattttc aatttgtata
     6001 gtactatttg catttttaag actatacttt ataggtattt cctcaataaa actactctct
     6061 atacataatg atatactttc cacattttca cttctattta ctaaaattaa cattctatca
     6121 ttattttcat taactctaat aaaagaaaat acagaatcat tattagtata tataaattct
     6181 gtatttccag aacttaaaag tttattctta tttctaattt ttataacatc tctataaaaa
     6241 ttaagcatat cttcgtcttc atttttccat ggataagttc ttctattatc tggatcaaca
     6301 cctccacaaa gacctgcttc atctccataa tatatatatg gtactccttc aaatgtcatc
     6361 tgtatagcta cagcaagctt cactaaatct acatcatcat ttaattccgt tttagctctt
     6421 gtaacatcat gtgttccaat taaatttaaa ttagacctaa atgattcttt tggataattt
     6481 tctttaatct gcatatatct attacaaagt tcatatgaat taatttctcc ttttaagaaa
     6541 gaaaacatgt tatttctaaa aggataaccc ataacagaat ctaattcttc acctaataaa
     6601 taacttcttc tctgaccata gctaatctta tttgatgcat cttcccatac ttcacctata
     6661 agaattgagt catcatctgc cttttttaat tcctttttta actctcttat aaacttagtt
     6721 ggtaattcgt ctgcaacatc tagtctccag cccttaatac ccatatttac ccatttattt
     6781 ataacgctat cattgtcata tattatataa tccatatagc tatgttctaa ttcatttata
     6841 tttggcaatg tcttaacatc ccaccaactt ttatattttt gaggaaattc ttcaaacata
     6901 taccatgaat aatatggaga ttctttagat tgatatgctc ctaaactatt atagtttcca
     6961 tacatattaa aatatttact atctgctcca gtatgactaa aaactccatc taatactatt
     7021 gatatacctt tttcttttgc tttatcaata agttctttaa atgtatcttc atctccaaac
     7081 attgggtcaa tttttttata gtcacctgta tcatacttat gattactaga ggcttcaaat
     7141 atagggctta gatatagtat acttacacct aattttttta aatatccaag tttattgatt
     7201 atccctctta aatttccacc atggaaatcc catcttataa catccccttg actatccttt
     7261 atgtacatag gtgtatcttc ccaatttcca tatatgaaac tatttttttt aggattatca
     7321 accttaccac tacgatttcc attattgaat ctatctacaa atatatgata aagtattcct
     7381 tctttgtacc atgttggtac tttaaaatct ttataaacag tgatttgata tttattaata
     7441 tcactataat tatattcaca agaatatcca ttatctctgt tttttccata aaataaagtc
     7501 tttatttgac catccatttc aacatcaact ttaaagtaat aaaaataaac acctgtacca
     7561 tcaaactttt caatcttacc acaaaagcac tttccaagtt tatcattatc taattcttca
     7621 tttaaagtta ttgttctcat ttcttcttct ctatttattt ctagggaaat agacttgata
     7681 ttgtatccct catttacttt aacacaaatg gtcaattcct catcaaattt taaagctcca
     7741 aacggagcct taaaattttt atcccaagag ttatattcta ttacactttg catttaatca
     7801 caccctttta aaccaaatgt cttttgcata ctcagaaatt gttctatcag aagaaaaaaa
     7861 tccagagtta gctatattaa ctaaagacat tttattccat ttttctttat ctctatataa
     7921 cctgtttata tctgcttgag cttgaccata attttcaaaa tctctcaata caaaatactc
     7981 atcattgtaa gtagtgagtg aattataaat acttcttcct tcttcgccaa gattaggaat
     8041 aaatccattt attaaatcat ctactaccct ttttatatcc atattagaat gatataggtc
     8101 aagtgaagaa tatccaccat atttattata atttagtact tgttctgcac taagtccaaa
     8161 taaaaacata ttttctttac caacctgttc acatatctct acatttgcac cgtcaagtgt
     8221 agccaaagtt atagcaccat tcatcataaa cttcatatta cttgttccag atgcttcctt
     8281 agttgtagtt gaaatttgct cactaacatt tgctgctggt attattattt ctgctaatga
     8341 tactccataa ttctctaaaa atactacttt taacttgtcc tttactctaa catcattatt
     8401 tatagtactt gcaacagaat ttataaattt aattatacat ttagccaaat aatatcctgg
     8461 tgctgctttt gcgccaaata taaaagttct tgggtcaaga ttcaaattag gattatcaag
     8521 taattcatga tacatatgaa gtacattaaa tatattcagt aactgtcttt tatacgcatg
     8581 caatctctta acttgaacat caaatatcga acttgggtct acatttaaat cgtatttatc
     8641 ttttataaac tttgctagat ttgctttatt attgtatttt atatcatcaa gtctttgtaa
     8701 aacagaggaa tcatttttaa atttttcaat attttttaat tgtaatgtat ctttcttcca
     8761 tgaatcacca attaaatctg taattaaatt gctaagttga ggatttgaac ttataagcca
     8821 tcgcctatgt gcaattccat tagtcttatt attaaattta tttggttcat cttgatagaa
     8881 atcttttaat acctctgttt caagaatatg agtatgaagc ttagcaactc catttacact
     8941 atgacttgtg acaatacata agtttgccat attgatattg tcacagtcta ttatactcat
     9001 tctttttatt ctatcttggt catatccttt attatttaat tcctctacat atcttctatt
     9061 tatttcttct attatcatat aaattcttgg taatagctct ttcatcatac ttacaggcca
     9121 tttttccatt gcttctgaca ttatagtatg attagtatag gacactgttt ttttagttat
     9181 ttcccatgct tcatcccaag ataaattttc ttcatcaagc aaaattctca taagttctgg
     9241 tatgcataag gtaggatgtg tatcatttat atgaattgct accttatcga ataaattatt
     9301 aatatttaat ttgttctttt tatattttct tattatatct tgtatccctg cacttacaaa
     9361 aaagtattct tgtttcaacc tcaacaactt acctgcatag tttgaatcat caggatataa
     9421 tacctgtgat atttcctcag tataatactt atgttttaaa gcctcttcat agctaccaga
     9481 ataatttaga gcatttgagg taagttcacc aaaatctctc tttggtattt cactcttaaa
     9541 caatcttaaa gtatttatac attggttttg gtatccgatt attggtatat cataaggcat
     9601 tgccattaca ggaaggtagt ttttatgaat tacttttaaa tgactacctt ccttgattaa
     9661 ttctacctca ccaccaaact tcaccattgt tgcttcattt ggtcttacag tttcccatgc
     9721 atatcgtcct tctgtaagcc agttatcagg cacttctacc tgataaccat ttacaaattt
     9781 ttgttcaaac agaccatatt tataccttat tccatatcct tgaccactta tgttcaaaga
     9841 tgccatagaa tctaaaaagc aagctgctaa tctaccaagt ccaccatttc ctaaggctgg
     9901 gtctacttca gtttcaatta aatcatccaa gttgattcct aattcagata aaccttctct
     9961 aacttcttct tcaatattta aatttaataa attagatttt aactgtctcc ctattaaaaa
    10021 ttctaaacta aaataataaa cttctttttt cttatctaac tttgtagcaa cccatttttt
    10081 tgctatctca tctttcaata gactacataa tacatttaac aattgttcat cagtagcttc
    10141 cttgatagat tgtgcatata agctatacat ttttacttca aatttttgct tgaatttctt
    10201 tttgcttatt gttaccaaaa aaaccactcc tttaatcaca tatgtctcta tatgtttcta
    10261 tatactcctt agctgatttt ttccaactat tatctgtttt cattgcattt tcaactaatt
    10321 taatccattt ttctttgtcc ttaaatactt tgattgcatt tttcaaacag aaaaacatct
    10381 catgagcatt gtaattttta aaactaaatc cattgccttc tccagtaaat ttattataag
    10441 gtgttactgt atctctaagc cctccagtct ctctaactat tggtaaagaa ccatatctca
    10501 tagctaacat ttgacctata ccacaaggct caaataatga tggcattaag aacatatcac
    10561 ttgcagcata tatctgttga gccaatgatg cattaaaagt aattctagct gatactttat
    10621 ctgaaaaatt agaatcgtaa tagttgaaca ttgattgata ttgatgttct ccagttccta
    10681 aaacgacaat ctgtaaatct tctctcataa gttctggcat catgtatgct attaaatcaa
    10741 atcctttttg agaaactaat ctcgaaacta tacctatcaa cggaatagat gaatcttttt
    10801 taagtcccaa tatatcttgt aatctcaatt tattttctac ttttttgtca attgagtcta
    10861 catcataatg aacaaatata tctttatctt ttgcagggtc atttaaatca taatctatac
    10921 catttaatat accttttaat tttcctgact cttttctaag taatccatct aattgttcac
    10981 cataaaaaga tgtttgtatt tcatttgcat aagtaggact aacagttata attttatctg
    11041 caaaatttat accagctttc ataaaattta ttgagccata atactctata tctccattat
    11101 caaagtattt ttgtggtaag tccaatatat catataaaac atgcttatca aatacacctt
    11161 gatattggag attatgtata gtatacatag tttttatatt tttatacccc tcaagggttg
    11221 catatctttc ttttagaatt aatggtaaca tccctgtatg ccaatcattt atatgtatta
    11281 catctggata aaaatcaatt ctacttatag cttctaaaac tgcatctgta aagaaagtat
    11341 atctttctgc atcatctcca tatccataga tactctttct ttcatcttct cttctaaaat
    11401 aaaattcatt atctataaag taaaatttta caccatctaa ttccatttct aaaagaccac
    11461 agtattgatt tctccatcca acacgtacac taaacacagc tatttctttt agttgatctt
    11521 ttaaataact tggtatagtt gaatatttgg gcattattac ccttacatct acaccttctt
    11581 tttttaattc tttaggcaat gcataagaaa catctcctaa tcctccagtt tttgcaaagg
    11641 gccaacactc tgctgttaca taaaaaacct tcattagtca ttcccccttc taaaaaattt
    11701 atttatatat ttgtattctt ttccactaca agaggatatt tttcatctcc tcttaattct
    11761 ttcccatttg atacactcgt atttttatct aatattgcat tatatagttt tgcatttgac
    11821 tttattacac aattttgcat tactattgag ttctctataa ctgttccttt ttcaacattt
    11881 acctttctaa atatgatact atcttttaca gtaccttcta ttaaacaacc agatgctata
    11941 aagctatttt ctactttagc actatctgta taaattgtag gtgattcatt cttttctttt
    12001 gtaaatatct ttctttcaga atataataat tcatctgcaa cttctaaatt taataaatct
    12061 ttgctcattt caaaatatga ttcaacagaa tttacacatt ttagatatcc tgtatattca
    12121 taggctccta ttttcatatt ttctgcttct tcaataataa attcttctaa ataacaataa
    12181 ttgcctttat ttacaatgtt atatatacat tcaacaaaat cttcacgctt cataatatat
    12241 gtctccatac atatgtttgc tctagggaac ttacctaaat tatttcctac atttattacc
    12301 ctattgttac tatctaaatt tagagttaag ttaccagcaa aatctttatt tgcattattt
    12361 acatttttat atattatagt tatatcatta tgagattttt tatggtattc caatgcttga
    12421 gaataattta aattgcatag catatagctt ggagctatta aaatatattc ttcttcactc
    12481 ttttctatat aatctagatt agctaagata gtatatatat caccttctct atgtgagtaa
    12541 gtatttctat acttagtgtt ttctggacta aaaattgata ggccaccttt ttttctactt
    12601 aaatcccaat ctttaccact acctatatgg tctgttaatg atctgtattt ttcttttgcg
    12661 aatattccaa ctttagtgat tcctgaattt atcatattag ataaagcaaa gtctattatt
    12721 ctatatcttc cagctattgg tgtagatgct attggtcttc catagttaag tttgtttatt
    12781 gctgggtctc cttttttgtt taaatttatt atccctaaac attcatttct catcttaaag
    12841 acctccttct attaatacgc atctaggttc gatattttca tactcagaaa ctacatttat
    12901 ttcattattt acattcttta tctgaacatt atcatttata gttgcacact cacctatcat
    12961 agctttttct atagttacat tttcacctat tacaacattt ggcattatta ctgaatcaat
    13021 tactttactt cctttaccaa caacaactcc atgtgataat acagagttac ctacttcacc
    13081 taaaattcta caaccatcag ctatcattga tctatgaaca tttgcatttt tacctatata
    13141 ttgtggaggc attgccatag tatttgtata tatcttccac ttagggtctg ctaaatcaag
    13201 tgtttctgga gattttatta tatccatatt agcatcccat agactttgta tagttcctac
    13261 atctctccag tatcctttaa atggataagc atacattcca acattatctt ctaacatttt
    13321 aggtattaaa ttttttccaa aatcatcata atttatttct ggattttttt ctgcttcctt
    13381 aaaataattt ctcaacattt tccaatcaaa tatgtatact cccatagatg ccaaattgct
    13441 cttaggttca cttggttttt cttcaaattc atagatactt gaatcttcat ttgtattcat
    13501 tatcccaaat cttgaagctt catcccaagg aacttcaatc actgctattg tagctttaga
    13561 gcctttttcc ttatgaaatt ttaacatttt gctataatcc atcttgtata tatggtcacc
    13621 agataatatc aatacatatt ctggattata ggtatctaca aagtccatat tttgatatat
    13681 cgcatgtgct gtaccattat accaatttcc ttctttttca ttcataaatg gttgtaaaac
    13741 atagacacca ccatttattc tgtccaaatc ccaatgactt cccatgccta tatgtgaatt
    13801 taatatcaac ggtctatatt gagttaaaac acctacagta tcaataccag agtttgaaca
    13861 attgcttaac acaaaatcta taattctata cttacctcca aatgatacag ctggtttggc
    13921 aattcttttt gtaaaaacac ctaatcttga accttgccct cctgccaaaa tcatagctaa
    13981 catctctttt ttcatttaat gacactcccc tcatctagta attaatattt ataattgcat
    14041 ttttactttt ataaacttta tcagtcaata aatgtcgtgt ataaatgttg cttaaataat
    14101 accttaataa aaataaaata atatcaacta tacaattgat ataatgtata ccccataatg
    14161 gacttaccga cgtatacatt attttccata agcactatag tatttattaa tattcaatta
    14221 ttggttaaaa aataatacaa attttatttt ataaatataa aaacattttt tataaatcct
    14281 ttgtgtcata tgaacatgct tattttttaa tttgttaaat tcgtaatagc aaaatataat
    14341 ctaatatttg ttaaataatt atccaaagaa aatcaagtaa ttattaatca actttatttt
    14401 ttaattgata cttctttgtc tataatttaa acaaaaggat ataaactttt aaattattta
    14461 ttagttttct tagtattaat gtttatattt ttataaatat atattaataa tataaataga
    14521 ctaactaaaa ccatgcttat ttgctatatg ttttatatta tattatataa cactttttac
    14581 attagtaaag gataaattgt ataaagattc tgttaattta tttttataat ttcatctttc
    14641 taataaaaac aaagaagaag acttaaaaat ttataagtcc tcttcttttc aacgtgcatt
    14701 tttgtgctat atttaattaa ttcgaccttt aatttccata tccttcctat gataacaaaa
    14761 ctcttttatt tttttaatga ttcattatca tttaaaactt cttttatatc aagtacttct
    14821 ttgttatcat cactcataac ttcctttatt cctttgaatg ttcctaggaa attaactgct
    14881 tctgaaggta aaaccagttt tgttgactta ccttcagcca ttttttcaag agcttccata
    14941 gattttaatg ctagaatatt attgtctata tcagcctctt tcattgctga aaaaactaat
    15001 tttaaacctt ctgctgttgc catttgagtt ctttttatca tttcagcttc accttgtgcc
    15061 ttagcaatag ctgtctgtct tatagcttca gcttcacctt ctgccactaa tatagcagat
    15121 tctttttcac cttctgctac acgtaccata gcttcttttt tggcttctgc tgttaatatt
    15181 gcagattgtt tttcaccttc tgcttgaagt attgcagctg acttattacc ttctgcttga
    15241 agtattgcct ctcttctttc tctttctgct ctcatttgtt tttccattgc aacttgaata
    15301 tcctgaggag gcattatatt ttttaactct actctattta cttttatacc ccatttatct
    15361 gttgcttcat caaggatagt tctcattttt acatttatta tatctcttga tgttaatgtt
    15421 tcatctaaat caagttcacc aattatattt cttagtgttg tagctgttaa attttcaata
    15481 gcagctattg gattagctat ctcaaacaca tatctaactg ggtctgtaac tttataatat
    15541 acaactgtat caatctgcat agttacatta tctttagtta taactggttg aggtggaaaa
    15601 tctattacaa tttctctaag gtcaattaca tatgccattt tatctaaaaa tggtattaag
    15661 aaatgtacac ctgtttcagc tactttttga aacttaccaa gtctcattat tatacctact
    15721 ttagattgtt ttataactct tatacaagtt aaacttattg ctacgactac tactattaat
    15781 acaatactta aaacaatttt agtacccata ctataaatcc tcctttattc tattggtttg
    15841 tcacattaac tgtggcgtct acttttttaa caactaattt taccccttca atttttaata
    15901 cttctactgt agaacctttt tctatctttt caccatctat agaaatagcc gtccatgttt
    15961 catgttcaac tacaactaga cctgtgttat ttggagaaat ctcttctgta acaatacctt
    16021 ttttagacat cattgcttgt aaattagtgt tagatttata gcctttatct ttttttacta
    16081 tttttttagt agctacgact aacattgcta tagaaattac tgcaaatatt aaaatttgta
    16141 agaaaatact ctctataaag ctacttaaaa atataagtat tacagctcct acactaaacc
    16201 atatcaatgt taagcttggt gttaacattt ctgctattcc aaataagact gctactatca
    16261 accatattaa cttcatacta tctaccctct tttcatatga attataaaac cctatataaa
    16321 ttatatgttt atacaatgtt tttgaatata aatttaaatt acaaaacaat aaaataaatt
    16381 aattaattaa ttaattaata gtattatatc aacatacttt gttaaatttg ttacaaagta
    16441 gtatcaaata tcaccaatta tatatccaac aactctttca ttgttaatga aatgttactt
    16501 attaaatccg tagcatttac cgtatacatt gctttgctca gtttatctcc tatatagcca
    16561 tgtatatatg ctccactaac tgtagcttcc aatatatcca taccttgacc tataaatgaa
    16621 gtaatcattc caagcaaaca atcacccatt ccaccagttg ccatacagct atttcctgta
    16681 ggatttatat atgttttttt accatctgtt atgacagttt gataaccttt taaaagcacc
    16741 accagattat atttttgagc aaattctttt gcaacatcta ctctatgttc tcttatatac
    16801 ccaattgaat ctcctgtcaa cctggccatt tctcccaaat gaggtgtaat tacaaatcta
    16861 tttttccatt ctaaaaactt ataacatctg tccttcataa cgttcaatcc atctgcatct
    16921 aatactattg ggcaattaga attttctact atcttaagta atttatcaaa tgtttgacta
    16981 ttatctccca tacctggacc aaaaccaatt gcatcactag aattaagtaa tttatttaat
    17041 ctttcttctt caaaatttaa agtcattgct tctgtaagtc taatagatac cttttcttgc
    17101 acatcttcac tactaattaa tgttacaagt ccactcccac tcttaacagc agattcagtt
    17161 gctatgaaac ttgcaccata aaatcctttt gaacctgcaa ctatagatac ttttccaaaa
    17221 tcacttttaa aaccatgctt atctcttctt ctaatattat tttttacaaa agtcttatca
    17281 gttatgaact cttcatcatg gtattttctt gtaataaaat ctggaacacc tatcttttct
    17341 acaactacat cacctataag tgcgctagtg tcatagttta gaaaacctct tttataaaac
    17401 tcaaagctaa tcgttttgtt tgctctaata caagttccta atacatttcc attatcgcta
    17461 tctatacctg aaggaatatc tatagaatac gtatttttgc tattatcgtt tactatgtca
    17521 ataacttctt taaaaatacc agttatatca cgttttaatc cagtcccaaa tatagcatct
    17581 actacaacat cacttttaga tactctatct ttaaaaattg ttaaattttt attttttata
    17641 atattttgtt tctcaacttt aataatttta tctacttcat tttcctctcc ataatttttt
    17701 tcacttaaat catttttatt aatatttata atattaattc ccatatttaa aagtacattg
    17761 taatttattt tagagcattc acttagtttt tcaagattac ctactaaaaa tacgtttact
    17821 tcttttccat atgtatttag atgtcttgct attccaagac catctcctcc attatttcca
    17881 acaccacata caactgtata actattatac atgtctatat ccatattttt cattgcagat
    17941 ataaccgcat tttccatcaa tacaatcatt ggaatcccta cttcttctac acatgcagta
    18001 tcaacatttc tgcttaattt agatgtacct attagcataa attatcactc ctataaagtt
    18061 aaagacttct taaatactta ccaaaaatat ctattgaaat ctttttaatc ccataaatat
    18121 cataaataaa atcactaaaa ctaagagttt tgaaataatt taaaataaca aaaaattttg
    18181 aattaaaaca attatttaat ttattatacc atataattta agttattatg ttgatttaaa
    18241 acctatttac actaattatc taaatatctc tttattttta taatctttta tgacttattt
    18301 atatttttca tttttataaa aaaacaataa ttaagaatat aactatattc tacatgtaaa
    18361 aattttttta tttaaactca attttctgat aatttgataa tttttcaaaa tttatagttg
    18421 acttttattt tttactgtat taaactaatt actatacaaa acagaaaaca aaattttcaa
    18481 aattattaaa ttaaaaggag aggtaaatat gaagacttta ttaaacaaac aagtacgatt
    18541 ttttagtagc caatttagtt agggtttgta cctaagttaa gacaaattgt cataacatag
    18601 atacaagccc cttaggatta tgatttttaa ggattgtatc tatgttggct atagtaattg
    18661 ttgttaaagt ttttatttta tcatcataat atagagccac atggattata ctgtgtggct
    18721 tattcgaatt tttgccatac agttatatat actgtgtggt ttttttatat caaaatcatt
    18781 ttttaaaacc aaattttaaa aaccatttaa aatattttca aaggggtgtt ttatttatgt
    18841 caggtattat atctgtaatg acgcaaagtt taattttatc gattatggca ctgggggttt
    18901 atataactta caaaatctta gattttccag atatgtctgc tgatggtagc tatacaatgg
    18961 gtgcttctat tgtagcattt tctcttacta atggtatttc tcctgtagta gcaactttaa
    19021 tggctatctt atgtggttgt actgctggtc ttgttacagg gattcttcac attaagttta
    19081 agatatctaa tttactttct ggtattttag ttatgggaat gctatactct atcaatttaa
    19141 gaataatggg aaaatcaaat attcctctat ttagctttaa acacttattc aatggggaaa
    19201 tatctcctat agttttagcc ttagcttttg tattcatctg taaagtcctt ttagatttat
    19261 tcctaaaaac aggtcttgga tacactttaa aaggtgttgg tgataactct caaatgatta
    19321 aatctctagg tataaatata ggttctataa aaatactagg acttatgatt tcaaatggac
    19381 ttatagcttt atctggtagt cttatggctc agttcttggg attctcagat gtaaatatgg
    19441 gtataggaac tttagttctt ggaattgcct ctatcataat tggtattaca ctatttaaga
    19501 aatttacttt tatcaaagat actactgcaa taattgttgg ctcttttata taccaattca
    19561 ctatatactt tgcaatgagt ttaggaatgt tatcaactga cttaaaacta ataactgcca
    19621 tagttataat agctttccta gctactggta acttaaatat ttcactaaaa aaaaacaaat
    19681 gcaaagctag taccaaaaat aaatcagaaa aaagaggtgt tgtagatgtt acaaattaaa
    19741 aatctttcaa agagtttccc taatccatat ggtgaaccta atactatctt tgaaaattta
    19801 tcaatcgata tagaagatgg tgaatttgta agtatcatag gtagtaatgg aactggtaaa
    19861 tctactttat taaatataat atctgggctt ataaaagaat cttctggtca aattacttta
    19921 gatagtacta ctataacaaa tttagctgag tataaaagaa ctcaaatagt aagtagagtt
    19981 tttcaagacc caagccttgg aacttgtcct tctatgacgg ttagagaaaa tttatctcta
    20041 gcacttaata aagggaaatt attgaactta aaaaaatgtc ttcgtcataa aacgaatgac
    20101 ttggaacact tacttgaagg aatttctttg gatttaaaaa aatatttaga tattaaagta
    20161 caatatcttt cagggggtca aagacaatca ctatcactaa ttatgtctag cttagcaagt
    20221 cctaaggtct tattactaga cgaacataca gcagcacttg acccaaaaac atcaaatgaa
    20281 gtaatagagt taacagataa aatcgtaaga gagaaaaata taactacact tatggttact
    20341 cacaacttga aacacgctct tcaatatgga gataggttga taatgcttca taagggtgaa
    20401 gttgtattag atgtaaaaga taaagaaaaa aaagatttaa cagttgaaga aatcttagaa
    20461 aaatttgaat atgcagtata agaaattaaa atcttagttt taatcagaaa tatttataat
    20521 ctatcatatg aatatatgaa caaatataat tattaaattt taagggagga aaataaaatg
    20581 ataaaaagta aaaaaatatt aagtttaatt atagcaggag tacttggtgt atcaatgctt
    20641 actggatgtt ctcaaaatga tggctccaat gcttcaaatg aaaataaaga aacagatagc
    20701 aaaaaacaaa aaaatatagg tattactcaa ttagtggaac atccatctct ggataaagca
    20761 aagaaaggat tcatcaaagc acttgaagat aaaggctata aagatggaga taatataaaa
    20821 atagatttcc aaaatgcaca aaatgatatg cctactacac aaagtattgc tagtaagttt
    20881 gtatccgaca aaaaagattt gatatatgct atatctactc catctgcaca agcagcttat
    20941 aatgctacta aagatattcc aataataatg actgctgtta cagaccctgt agaagctgga
    21001 cttgttaaat ctcttgaaaa accaggtgga aatgtttctg gtacatctga ttatctttca
    21061 attgataaaa cattagaatt ggttaaaaca ttgactccaa aagcaaagaa aataggggtt
    21121 atatacaata ctagtgaagt taattcaaaa atccaagttg attctctaca tgattatgct
    21181 aagaaaaata attatgaagt agttgaaaaa ggaatcagct cttcaagtga agttaaccaa
    21241 gctatttcta gtttagttgg taaaatagat gttttatatg tccctactga caatttaata
    21301 gtttcttcta tgccaatagt ttctaaagtt gctaatgaaa acaagattcc tataatagcc
    21361 tctgaagaag gttctgtatc ttctggtgct ttagcttgtt gtggaataga ttatgaaaaa
    21421 ctaggttata aggctggaga acttgctatt gaagtattag aaggaaaatc tgttggcgat
    21481 ataccagtta ctacattaga tgaaactgaa ataataatta acgaagatac actaaaagca
    21541 cttgacatgc aaaagttatc agcagataat ataaagtata taaagtcaga tgaaaatgca
    21601 aaatctacaa aataaaactt attaatttca aaaaataggt aatatgaagt aggtaatatg
    21661 aaaactttat ataataagta ctcttatcca ccctaaccct ttgaaaattg tgcttattgt
    21721 agcaatttga atattgcata taaagttatt cattttccat aaaagtcgtc tatattgacg
    21781 actgattatg aaagttatat aactttctaa tcactacttg agctgtccaa aagaatttta
    21841 atattctcca gacagctttt ttttatgata tttgattgat atacatgtct agttattcca
    21901 tatttagtaa atattttgat aaaatttcca cattcactta taacttagga taacgttttt
    21961 ttcaaacaat acattaattt aaaagtattc tgagtataca ttatttagta ttttaattaa
    22021 atttagcagt tgacttttat tattgtataa tttataattt ataacaagtc gagaatacat
    22081 ataattttct gactaattaa aatattaaaa gggagagata attatgaata ctttattaaa
    22141 caatagaaaa tattattatt attatagcca ctatttttag ggtttgtacc tacgttttaa
    22201 catagataca gaccccttaa gactactaaa attttgggat tgtatctatg ttggctatat
    22261 tgtttataaa gttttcattt aactatataa gagccacata gattaaacta tgtggcttat
    22321 tcgtgttttt accacatagt tttgtacact atgtggtttt tttatacaca aaattagcaa
    22381 ataattaaaa ttataaaaat attttcaaag gagtgtttta tttatgtcag gtattatatc
    22441 tgtaatgacg caaagtttaa ttttatcgat tatggcactg ggggtttata taacttacaa
    22501 aatcttagat tttccagata tgtctgctga tggtagctac acaatgggtg cttctattgt
    22561 agcattttct cttactaatg gtatttctcc tgtagtagca actttaatgg ctatcttatg
    22621 tggttgtact gctggtcttg ttacagggat tcttcacatt aagtttaaga tatctaactt
    22681 actttctggt attttagtta tgggaatgct atactctatc aatttaagaa taatgggaaa
    22741 atcaaatatt cctctattta gctttaaaca cttattcaat ggggaaatat ctcctatagt
    22801 tttagcctta gcttttgtat tcatctgtaa agtcctttta gatttattcc taaaaacagg
    22861 tcttggatac actttaaaag gtgttggtga taactctcaa atgattaaat ccctaggtat
    22921 aaatatcggt tctataaaaa tactaggact tatgatttca aacggactta tagctttatc
    22981 tggtagtctt atggctcagt tcttgggatt ctcagatgta aatatgggta taggaacttt
    23041 agttcttgga attgcctcta tcataattgg tattacacta tttaagaaat ttacttttat
    23101 caaagatact actgcaataa ttgttggctc ttttatatac caattcacta tatactttgc
    23161 aatgagttta ggaatgttat caactgactt aaaactaata actgccatag ttataatatc
    23221 tttcctagct actggtaact taaatatttc actaaaaaaa aacaaatgca aagctagtac
    23281 caaaaataaa tcagaaaaaa gaggtgttgt agatgttaca aattaaaaat ctttcaaaga
    23341 gcttccctaa tccatatggt gaacctaata ctatctttga aaatttatca atcgatatag
    23401 aagatggtga atttgtaagt atcataggta gtaatggaac tggtaaatct actttattaa
    23461 atataatatc cgggcttata aaagaatctt ctggtcaagt attattaaat aaacataact
    23521 tgtctaattt agctgaacac agaagaactc aaatagtaag tagagttttt caagacccaa
    23581 gtcttggaac ttgcccttct atgactgtta gagaaaactt gtctttagct cttaacaaag
    23641 gaaaactatt aaatctaaga aaatgtcttc gttacaaaag agatttctta gaaaatttat
    23701 tggaaggtgt atctcttgat ttaaaaaaat accttgatgt tcaagtaaaa tttttatcag
    23761 gaggtcaaag acaatcatta tcactaatta tgtcgtgctt aacaaatcca tcagttttat
    23821 tacttgatga acatacagca gcacttgacc caaaaacatc aaatgaagta attgaattga
    23881 ctaataagat tgtaagggaa aaaaatataa ctacacttat ggttactcac aacttaaaac
    23941 acgctcttca ttatggtgat agattgataa tgcttcataa gggtgaagtt gtattagatg
    24001 taaaaggtaa agaaaaagaa caattaacag ttgaagaaat cttagaaaaa tttgaatatg
    24061 cagtttaaaa taatatatct attgtattaa actcggcttt aaaataaagt taaaattaca
    24121 ataattatgg ttactttgta ataattcata tgaatatatg aacatatata ataataaatt
    24181 tttgaggggg atataaaaat gattaataaa aaaagattgg caagtttgat tttagctggt
    24241 gctcttagta tatctatgct tacagggtgt tcacaaggag gagactctgg taattcaaaa
    24301 caagaaagta attctaaagg taaagaagtt aaaaaaattg gtataactca actggttgaa
    24361 catccagcat tagatgccac taggacaggt tttgtaaaag cattagaaaa gaacggattt
    24421 aaagatggag aaaatattga tatagacttc caaaatgctc aaaatgacat gcctactaca
    24481 caaagtattg cgagtaaatt tgcatctgat aagaaggact taatatttgc tatatctact
    24541 ccatcagctc aggcagcatt taatgctact aaagatatac ctatacttat tactgctgtg
    24601 agtgaccctg ttgctgctgg attagttaaa actcttgaaa agccaggcac aaatgtatct
    24661 ggaacatcag attttgtttc tgtagacaaa ggtttagaac ttcttaaaat atttgctcct
    24721 aaggcaaaaa ctataggagt tatgtacaat actagtgaag taaattccaa agtccaagtt
    24781 gatgctttaa aagaatatgc atctaaaaat ggatttaaag ttgttgaaaa aggtataact
    24841 acttcaaatg aagttaacca aggtatttct agtttagttg gcaaaataga cgtattatat
    24901 gttcctacag ataacttagt ggcttcttct atgcctatag tctctaaaat agctactgag
    24961 aataaaatac ctgttatagc agctgaatct gggccagttg aaaaaggtgc tcttgcttgt
    25021 caaggtatca actacgaaaa actaggttac aaaacaggtg aaatggcagt taaaatttta
    25081 aatggtgaat cagtatctga tatgcctgtg gctacatcag atgatacaga tatcattgtt
    25141 aatgaagata tattaaaagc tttaggtatg gaaaaacctt ctaatgaaaa tatttcttat
    25201 gtaaagacta aacaagaata gaaagatatt ttctatatac gattaatatg cctgtttcta
    25261 taaattaatt tatagaaaca ggcatatatt tttattttaa tgtattatct atttaaagat
    25321 tatatgtaaa tgctcttaat ttgtttgtat aaattttact tgtataaact ttatacaatc
    25381 atatttattc ttctattttc tttattactc tacatggatt tccaacagct acagtatttg
    25441 gtggtatatc ttttgtgact acacttcctg cacctattac tacattatca cctatagtaa
    25501 ttcctggtgt tatgattact cccccaccta tccatacatt atcacctatt tttacaggag
    25561 aaccatactc tatacctgaa tttctaagtt gtgcatcaat tggatgatag gctgtataga
    25621 tttgaacgtt tggagctaac attacattgt cacctatttc aattttacat acatctaaaa
    25681 aaatacaatc ataatttgca aagaaatttt cgcctacatg tatgttatat ccataatcac
    25741 acctaatatt ttgttctaca tttatttgct tgccaactga accaaatagt tgtcttaaaa
    25801 tatcttctct tttttcatat tcatcctcta aagtattatt aaacaatcta gttaattttt
    25861 tacaatactc tctttctttt actaacaatt catcatttgc atagtatcct ttcccagaca
    25921 acattttttc tttttcagtc atatagttta ctcctttttg ttataattgt atctaaagca
    25981 aaataaatat tcctgtggaa aatctaaata tattctgtca cctttcttaa atctcatttt
    26041 acttttttcc aattctattt gaataggtac acattcgtta gataaatcag tttttctaac
    26101 atatatagta tatgtaaaag gattttctac aatgttaatc aattcgaaac ataacttttc
    26161 atttaaatct tcattagaat ccaagacctt aatatgatgc tccctgattc ccacatattc
    26221 tatattatca cctatttctc tatttaatgt caactcgcat ccccagtctg tagcataaat
    26281 agtattttta tccagtctat ttaatttgga tatattttta caccctgtta tcttagcttc
    26341 tataaggtac tttggagatt caaagagctc ttttttaggt ctctttggaa gaccttctcc
    26401 tttgttgtac actataatat catcacaaac tcggtaagct tcttcaatat catgagtaac
    26461 aaatagtata tctcccttgt aatcttttaa catattcata agttcttttt ccatattgct
    26521 tcttaaatga tggtccaatg ctgagaaagg ttcatctaaa agtaatatat ctggagatgt
    26581 tgccaatgct ctagctagtg ctaccctttg ttgttgacca ccagataatt gccaagggta
    26641 tctcccctca aacccattta atttaagtat atctaagtac cttgctacta tttccttttt
    26701 ttcactctta cttagtttta aaagcccaag ttctatattt tgacttacag tcatatgtgg
    26761 aaacaaagca tagttttgaa ataaaaatcc tacctttcta tcttgtgttg ataaatttat
    26821 cttcttttca gaatcaaata gaactctatc atttaataca attttacctc ttgttggttt
    26881 ctcaagccct gctatacatt ttaatgtcat actttttcca gaaccagatt ctcccaaaaa
    26941 ccccagagta cctttttctt gtttaatttc tacctttagt ttaaaagagg ataaatcttt
    27001 ttcaatatcc acgtataagc tcaactatcc acacctcttt cctataattt tctgctgaaa
    27061 ttccgaccaa taatttagta ataaaatcat tgctatagat attgctacaa taatcataac
    27121 ccacatcata gctttattca tatctccgcc ttcaacagca aaaaatatag ctattggcat
    27181 agtttgagtt tttccaggta tatttccagc tatcataagt gtagcaccaa attctccaag
    27241 agctctggca aacgacagca ccaatccacc aattattcca ggccatgcta atggaactgc
    27301 aatcttaaaa aatactttcc attcattaag acctaatgtt ctagcagctg acaacatatt
    27361 attatcaatc tgttcaaaag ctgaccttga agttctatac atcataggaa aagacaccac
    27421 tactgctgaa attacagttg ctgtccaact aaatattaaa gtcctatcga aatttaataa
    27481 aaactttcct ataaatccat tcttcccaca tagtaataat aaaaagaaac ctacaactgt
    27541 tggtggcaaa attagtggaa gtgtaaatag tccatctata agacccttcc acttacctct
    27601 atagttagcc ataatatatg acacaaatat tcctattaca aaagttatta ttgttgacaa
    27661 aatagatgtc ttaagtgata tccataaggg tgaccaatct gttcccatct ttccctcctt
    27721 aattttaaat ggaaatagtg aaactaataa ctctattaat ttcactattt ccattttatt
    27781 ataatacaca attattttca attttcattt atttatatat aatttatact taattacaca
    27841 taatttattt ctaagtttat tctacttttt tatatccaaa ttcttcaaaa atcttttgtc
    27901 ctgactcact taataaaaat tcttcaaatt tcttagcagc atctacgttt ttactagctt
    27961 taattactga aactggatat gtaataggcg aatgagtttt ttcgtctgtt ttttcaacta
    28021 cttttatctt atcattattg acagtatcac tgaagtaaac gaatccaaca tcagcatttc
    28081 ctgattgcac ccatgctaaa acttctttta catcttttgc aaatactagc ttatctttta
    28141 acttatcttt taaatttaaa ttagttaaca cctcatctgc atacttacca gctggaacac
    28201 tttcagcttc accaacagca attttcttca ctttatctgt agtcaaatct tccatacctg
    28261 atacactact gtcagcagaa gaaataagaa ctaaatcatt ttttactaaa tctttcatag
    28321 tatcagaaac taataacttc tcttcatcca aagctttcat ttgtttttga cctgctgaaa
    28381 taaataaatc acaaggtgct ccttgttcta tttgttgttg taatgagcct gatgctccat
    28441 agttaactgt aagttttaca tttgaatcaa cttttttata ttcttcttca atctttgcca
    28501 ttgcttcttt taaacttgca gcagccgata tatttaactc tactgaatca ctacttttag
    28561 ttgttttttc ttgttttcca tcatcttttt tgtcttcatt actattgcac ccaactgtcc
    28621 ccaaagttaa acatgcaact aatcctaata ttcccaatat ttttttcata acaatctccc
    28681 tttttgtaaa tttgatacac attttaacat gttttattat gttttatcat gttttgttat
    28741 atatagttta attatatata catgataata aattttcaag taatttattt acactacttt
    28801 taaatatttt gctacatttt ccttttttta atgttaaaat aaccttatat ggaggtggat
    28861 tatggactca ttatcatctt tgacacctgt cgaggtagct gaattattaa agataacaaa
    28921 aaatactgta tatgaattaa tcaaaagagg tgaacttcct tcttataaag tagggaaaaa
    28981 aataagagtt gatactaaag atgttgaaga atatatcaac agccaaaaaa ctggtaaagt
    29041 aaaggataca catttcaaca ataaaaatat agatataaat aataatttca aaattattat
    29101 ttctggtcaa gatgtaatat tagacatttt agctaggtct gttgaaaaaa aattggatgg
    29161 aataagtaca tttcgctctt atataggtag ttataatgct ttgtatgagt tatataatgg
    29221 cagagtttct atagcatcat cccatctatg ggatttcgaa acggatgaat ataatagcac
    29281 ttttgttaaa aagctattgc caggaatacc atgtgtactt ataaatctag cttatagaat
    29341 gcaaggtttc tatgttgcta aaggaaatcc taaagagata acaacctggg aggatttaac
    29401 aaaaccaagt ataaccattg taaataggga aaaaggttct ggaactaggg ttttactaga
    29461 tggtaaactt agacttctaa actttaatgg taaacatata aaaggttatg ataatgaaga
    29521 attatcacat cttggagttg caagtactgt ttctcgtgga atagcagatg ttggtttggg
    29581 aaatgaaaaa gctgctttac aagtaaataa tatcgacttt attcctcttc acaaagagcg
    29641 ctatgattta gttattaaaa aagaagactt acaaaatcca gtttaccaaa ctataattaa
    29701 cataataaac tctcctgagt ttaaagctga acttcaaggt cttggcggat atgatttaac
    29761 tgatactgga aaaactatag caaaagttta agattaaaat cgcaatctat tttataagat
    29821 ttataatttt tcacaaaatt tataacttaa acacgaaata aattgcgatt ttagtgtctc
    29881 aaaaaattta tgtctttcat tttatcatcc aatacaaaat ataatataat taattgtgca
    29941 atcatattat attaatatat atttacataa tagtattttt ctttaatgta gattaacata
    30001 tgatatgttt taaacatcaa tccccttgct ttcttatata tatttggcaa cacatatgag
    30061 tttaataaat tatatacaat gttgctttct tcttgtattt tttcaaccaa caagttattt
    30121 ataaaattac ctttctcatt ttcaataatc tcactccaat ttatcttaac ttttaatata
    30181 tatcttccca ctaggtatac acactctaca ataaataata aaaatacaat gcagtcagta
    30241 cctgttgtct tatataaatt acccgatact aatggctttg cgaagaaatt ataaaaattc
    30301 aaagtatcac ccgtataatc aaaaagtatt aatagcactc ctagaactct caatacttta
    30361 atattcaaca tgtttttatc tttattattt ttgtttttca tatatactac ctctcttttc
    30421 tttagatttg attgtaatct aatactaact cttttatttg aggtataaat gaatttaatt
    30481 ggtagttatt ttcattttta ctagaaatta attcacatta ctaaacaaaa cttatattta
    30541 aacataaaaa tagcctatct atcttttaat aaatacaaaa ataaataagc tactaatatt
    30601 caattaactt ttatcactta aaacattact atctataaat ttaaatattt tattgaagta
    30661 tactgtacta tcatgttcaa atccatcaac atgaccaata ccttctataa gccataggtc
    30721 ttttttatca tgtttaacta aatcatacat tttcttgcta ttttgataat tacaaacagt
    30781 atcttttgtt ccatgtataa acagtatggg tacattagat ttctcaactg actcatatgg
    30841 ttttacatca ctgtaccaaa atccagattt aaacttatta tataaatctc cacaagtcac
    30901 cacataattg attaatatat ctggtattcg tttttctagt actcccattc taattgcatc
    30961 tttcatttca gaataaggag aatccagtat ataaaaatcg accttatcat cttttgaatt
    31021 tatctctgaa tgcatagcag ctgtccctgc ccccatggaa aatccatgca cacctaatct
    31081 cccttcagga aatttatttt ttacaaattt aactagacta tctaaatcat acctttcata
    31141 aagaccaaat gtgtaattat ctccaccact attaccagta tttctttgat tataaactaa
    31201 tacattataa cctttatcta aatatctata tgctaccttt aacatttcat agtaactact
    31261 tccaattcca tgaacaagta tcatagtatc tcttgtcttt atatttgaag ttataaaaag
    31321 actttcaagc ttgtaattat tagaactttg tatcattaat tcagatgtct tgtagttttt
    31381 taatttctcc agtggtttat cttttctctc agaaaatatt tttactatat cttcgttttt
    31441 tattaactgc tctaaaccaa ctgaactatt atacactaat tttccaaa
//
LOCUS       DAEPHU010000049        31166 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 01A10CD0081
            SAMN05941466-rid12468953.denovo.049, whole genome shotgun sequence.
ACCESSION   DAEPHU010000049 DAEPHU010000000
VERSION     DAEPHU010000049.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941466
            Sequence Read Archive: SRR6291087
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 31166)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 31166)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068158.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 22:43:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,892
            CDSs (total)                      :: 3,805
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 87
            rRNAs                             :: 8, 1, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 55
            CDSs (without protein)            :: 55
            Pseudo Genes (ambiguous residues) :: 0 of 55
            Pseudo Genes (frameshifted)       :: 21 of 55
            Pseudo Genes (incomplete)         :: 28 of 55
            Pseudo Genes (internal stop)      :: 16 of 55
            Pseudo Genes (multiple problems)  :: 8 of 55
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..31166
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941466-rid12468953.denovo.049"
                     /strain="01A10CD0081"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            <1..490
                     /locus_tag="KR231_002333"
     CDS             <1..490
                     /locus_tag="KR231_002333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HBH0004700.1"
                     /translation="NKLAKLQRELSRKTIGSLNRNKARLKVARFQEHIANQRKDFLQK
                     LSTKLIKENDIICIEDLQVKNMIRNRKLSRLISDVSWSEFIRQLEYKANWHGRQIVKV
                     GKFFASSQICNKCGYKNEEVKDLNIREWICPSCNETHDRDINASINILKEGLRLITIQ
                     NK"
     gene            623..2128
                     /gene="ade"
                     /locus_tag="KR231_002334"
     CDS             623..2128
                     /gene="ade"
                     /locus_tag="KR231_002334"
                     /EC_number="3.5.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenine deaminase"
                     /protein_id="HBH0004701.1"
                     /translation="MSPGFIDAHMHIESTMVMPIELSKKLLKSGTTTIIADPHELVNV
                     KGVSAIDFLLESTKDIPLNVYIMVPSSVPATSFETNGVGKFSAKDMESYVNNPRILGL
                     GEVMCFNDVINSENEILDKLELFKNKVVDGHAPNINGKSLQTYVCAGIENDHECITFD
                     EVYEKLRAGLKILIREGSAAKNLKSIVSGMLKHNLPIEEFMFCTDDKHLDDIEKQGHI
                     RWNIKCAIDLGMEPVRAIKVATYNSAKAYGLRKIGAIGAGYKADIVVLNDLDKMEVDS
                     VYKDGNLVNEEMFSNYNYEIKDKELLNTVKFKYINKEKIQLKVSEKNYVMEIVPYQIL
                     TNKVYESLPCADGYFVPNKEYSKLCVVERHRMTGNVAVAPLKGFGIKNGAIATTVAHD
                     SHNIIVAGDNDDDILVAINYLKEIQGGYVIVSNGKVLAHLSLQVAGLISTFTAEEVQE
                     ITDNMLEIARKMGVPEYVDPFITLSFMALPVVPQIRLTDLGLFDVEEFKFI"
     gene            2480..2944
                     /gene="bcp"
                     /locus_tag="KR231_002335"
     CDS             2480..2944
                     /gene="bcp"
                     /locus_tag="KR231_002335"
                     /EC_number="1.11.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002586316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin-dependent thiol peroxidase"
                     /protein_id="HBH0004702.1"
                     /translation="MLSIGTKAPEFTLEDKDGNKVSMSDFKGKKVVVYFYPKDNTPGC
                     TRQACAFRNAYDGFKKEDIQVIGISKDSIKSHQKFAEKHELPFILLSDPDLVAIKAFD
                     VWKEKKMYGKTALGVVRATYIIDENGIIEKVFEKAKPDTNAQEILEYLEKQE"
     gene            2954..3697
                     /gene="yaaA"
                     /locus_tag="KR231_002336"
     CDS             2954..3697
                     /gene="yaaA"
                     /locus_tag="KR231_002336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peroxide stress protein YaaA"
                     /protein_id="HBH0004703.1"
                     /translation="MIIMLSPAKNMKNIEVFDRDLSLPCFIDNTKEIVENIKTFGIED
                     FKNKMKINEKLAVLNKNRFESIKFDRLGNPAILTYDGIQYKNIEAENFTRKDEEFANS
                     CIRIISGLYGVVKPYDSIYEYRLEMQTKLRVGEFKNLYEYWGNRIYKELIKEKTAIVN
                     LSSNEYSKSIEKFIKDSDTYITCTFKVNKNGILKVESTQAKKARGMMTKYIVKNRIRD
                     IEELKKFNLEGYKYKENLSNNSEYIFVKE"
     gene            3825..6482
                     /locus_tag="KR231_002337"
     CDS             3825..6482
                     /locus_tag="KR231_002337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HBH0004704.1"
                     /translation="MENHKQMPWHSRATHEILESLDSSEEGLTDTEAEKRLKENGLNE
                     LRKKPPRTTLQMLWSQITDAMVMILIGAAILSLIFGEFTEAFVILIIVTVNAVIGIVQ
                     EKKAESSLEALKNMNSPTARVMRDGEENVIPASNLVVGDIVFLEDGAMVPADLRLIET
                     SSLKIQEASLTGESVPSEKDADTILPKECVLGDRSNMAYTSSIVTYGRGVGVVVATGM
                     DTEVGNIAHLLDSQDDFDTPIKRKLNTVGKTLSVIGIIVCVVIFAIGAFYQRPLLPMF
                     MIAISLAISIIPEGLPATATIVMALGVQRMAKRNALIRKLPAVETLGGATVICCDKTG
                     TLTLNKMTVTHIAVNGDFESGKVTSIDTASEKHPLVYKEIVYAGALCNDACINPDKTD
                     EILGDPTEGALIFMAKKFGIDQEALEEEYPRVFEQPFDSDRKCMTTVHNIDEKIIAYT
                     KGAVDEILDLCTKILTSKGERNITEVDKKNIHELCLNMSKDALRVLGFAKREISSIPK
                     EDSENIEYDLTFIGMVGMIDPPRTEVIDAVSTCKEAGIRTIMITGDHKVTATTIAHEL
                     GIWSEENTVISGDELDNLSDDELDEAVKNTTVFARVSPFDKLRIIQSLKRIGEVPAMT
                     GDGVNDSPALKSADIGIAMGISGTDVAKDSSDMILMDDSFTTIAYAIKEGRRVYRNIQ
                     KVIQFLLVGNIAEILTLFVAILLNWDTPLLAVHILWVNLATATLPALALGVDPPSRNI
                     MKHQPVKSTTLFEKNLIQRVVTQGIFVAIMTILAYKIGLNIENHSVGQTMAFCVLAFS
                     QMLRAFSQRSNTDSMFNRNNGKNPFLLISFLTSAFLIAVILFAPVFRNAFNLTVLNNL
                     EWLITIVLAIMSVIQVEVGKIIKRKKLKK"
     regulatory      6536..6638
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00162"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="SAM riboswitch class I; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="S-adenosylmethionine"
                     /db_xref="RFAM:RF00162"
     gene            6748..8013
                     /locus_tag="KR231_002338"
     CDS             6748..8013
                     /locus_tag="KR231_002338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-acetylhomoserine
                     aminocarboxypropyltransferase/cysteine synthase"
                     /protein_id="HBH0004705.1"
                     /translation="MYNKETICVQGNYKPGNGEPRVLPLYQSTTFKYSSIDQLAELFD
                     LKVDGHIYSRISNPTIQAFEEKISLLEGGVSSVAVSSGQSANMLAVLNICKSGDSILC
                     SSKVYGGTFNLLGPSLKKFGIDLISFDLDSSEDEIVELAKENTKVVFAETLANPTLEV
                     IDFEKIANVAKRINVPFIVDNSLASPVLCNPLKYGANIVTHSTTKYLDGHASSVGGII
                     VDGGNFNWDNGKFPELVEPDPTYHGISYTQKFGNAAYATKARVQLLRDYGNCLSPFNA
                     YLTNLNVETLHLRMERHSENALKIARFLEKHENVDWINYPGLEDNKYYENAKKYLSRG
                     CSGVLSFGVRGGLENAKKFVEKLQIASLVTHVSDVRTCVIHPASTTHRQLTEEQLIAS
                     GVLPSLIRLSVGIENVEDLIADLNQALNF"
     gene            8043..8933
                     /gene="metA"
                     /locus_tag="KR231_002339"
     CDS             8043..8933
                     /gene="metA"
                     /locus_tag="KR231_002339"
                     /EC_number="2.3.1.46"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine O-succinyltransferase"
                     /protein_id="HBH0004706.1"
                     /translation="MALILPKGLPVINKLLDEGIDVIYKEDFKKELKYEENIDTKIAI
                     LNLMPIKIDTELDLLRRIDKTGFNVSVEFIKISTRESKRSCNEYVKEFYKTFDEAKGE
                     YFDGFIITGAPVEQMEFEEVDYWNELEEIMDYSKRKTKSTLYICWAAQASLYKYYNVK
                     KLPLSQKCFGVFKHKVDKDSKIVDGFENEFFAPHSRHTTVNIEALKENKELSIVSHSK
                     EAGPYIITNSRDVFVMGHSEYDKYTLDKEYKRDINKGDKISIPQNYYINDDPSEEPTV
                     KWKKHSELLFRNWIKNYLIQ"
     gene            9421..9864
                     /locus_tag="KR231_002340"
     CDS             9421..9864
                     /locus_tag="KR231_002340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HBH0004707.1"
                     /translation="MDEMSFKKELLELTRDINMKFTTLLSDFYQPLGITAVQALILSE
                     LCEHGEKKISDLGKNLNMTNSNVSVICQRLEKNGFLNRIRDIEDQRIVKVKVTNKSLD
                     IQEHISSSIFDSYFENMTSEKLQDMEDIIEGLEKLNKLLTYIDCK"
     gene            9895..11712
                     /gene="ftsH"
                     /locus_tag="KR231_002341"
     CDS             9895..11712
                     /gene="ftsH"
                     /locus_tag="KR231_002341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent zinc metalloprotease FtsH"
                     /protein_id="HBH0004708.1"
                     /translation="MDEHKPQKRSALYYYTVIIIVVMFLNALIFPSLMDKKMVEIDYG
                     KFLTMLDTGKVKSVEIENNRIAINPSSSKDKNIYITGRMDDPELVDRLKNAKVEFTKV
                     IPKENSPLLSILLTWIIPIGILMLFGNLMMKSMQKRMGGNAMQFGKSNAKMYVSAQSG
                     KRFNDVAGQDEAKEALTEIVDFLHNPEKYKKIGAQMPKGALLVGPPGTGKTLLAKAVA
                     GEANVPFFSISGSEFVEMFVGMGASRIRDLFKQAKEKAPCIVFIDEIDTIGKKRDNGS
                     GLGGNDEREQTLNQLLSEMDGFDGGIGVVILAATNRPDSLDKALLRPGRFDRRIPVEL
                     PDLGGREAILKVHAQNVNVSSDIDYNAIARSTSGASGAELANIVNEAALLAVKSGRDI
                     VEQQDFDESVETVIAGYQRKGAVISDKEKKIIAYHEIGHALVAAMQKHSAPVHKITII
                     PRTSGALGYTMQVAEDESVLMSKEEAIDKITTFTGGRAAEEVIFNTCTSGASNDIEQA
                     TKIARAMVTRLGMSEEFDMVALETVSNQYLGGDTSLACSSDTAAKIDEEVFKIVKACH
                     KNAIEILENNIDKLHELANYLLEKETITGDEFMEILNLN"
     gene            11890..14592
                     /locus_tag="KR231_002342"
     CDS             11890..14592
                     /locus_tag="KR231_002342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase KdpD"
                     /protein_id="HBH0004709.1"
                     /translation="MDRPNPDILLEKIKNEEEKLSRGQLKIFFGYAAGVGKTYSMLES
                     AQNLKKVGVDVVVGYIEPHTRPETLALLDGLEILPVKEIEYKSIKLKEFDLDAALARK
                     PEVILVDEFAHSNVAGLRHTKRWQDIEELLLAGINVYTTVNVQHLESLNDIVEIITNV
                     SVKETIPDKFLDTNTQLELIDVEPDVLLERFNEGKIYKKEQATRAKNNFFIKDNLVAL
                     REIALRKTAERVNKEVQMTRLSKGDVTVIPTSDTLLACISPSPSSAKVIRTASRISDS
                     TFAKWIALYVETPNTARLPFDEQKQLQNNLKLAKKLGGEIIVLHGENIIEQILRIAKL
                     RNVTKIVIGRNHSSNKRFSKRFKKDIVDKLIDEVDYIDIHIIPYKFASDVKYKPKKDK
                     SSIKSKFKISKVDFIKLIFITLMISILAYAVQSMGFIRENILLIYMLGVVLVSMWTKG
                     YSTGIISSVFNIVLLNYFFTAPLYTLSIADSNYIVTLVVFSIVGIITSTLTSKIQHEA
                     ETAAKREENTKMIYQIIKGFLRLSNKDDIVNKGIELLSLSLSRDVICYLNVDKHNKSK
                     LYKKNTNNKDKNDLDSEDEKAVASWVLSNSTVAGNDTDTLPGSKGYYIPIVGMNLTLG
                     VVGISCIDSKLDTEDISLIETIIAQMAIALDREILSEAKENTNLEIERERLRSNLLRA
                     VSHDLRTPLAGISGAVSTIIKNKGTIGQDIIDELLSGVYEDTQWLIRLVENLLSMTKI
                     DEGKLEVKKHSELVEEIISEALQKIKKRIENALIDINIPEQILFVPMDAKLIEQVLIN
                     LIDNSLKYSKEDCKIEINVYEKDDYVWFEVSDNGPGISKELKKHIFDRFFTGEEGAKD
                     SRKGVGLGLSICKSIIQAHKGEIMVENNKDKGSTFKFSLPKENE"
     gene            14626..15324
                     /locus_tag="KR231_002343"
     CDS             14626..15324
                     /locus_tag="KR231_002343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBH0004710.1"
                     /translation="MSKKLILLVEDDKTIRKFISTALLTQDYDVKEAITGKEGISIAV
                     SYSPDVVLLDLGLEDMDGIEVIKAIRQFSNIPIIVVSAREQDRDKVEVFDAGADDYLT
                     KPFSIVELLARVRVAFRHSQVEAQQKDDVKSTFEVDKLLIDFDKRKVIVDDVEVHLTP
                     IEYNILSLLAKYHGKVLTHNFIIKEIWGSVIGNETKSLRVFMATLRRKIEKQPANPRY
                     IITEVGVGYRLNDE"
     gene            15681..16637
                     /locus_tag="KR231_002344"
     CDS             15681..16637
                     /locus_tag="KR231_002344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CorA family divalent cation transporter"
                     /protein_id="HBH0004711.1"
                     /translation="MYILNLNTRETIEDFRDKFYVAENSYLILSAPKNLKLLKETLDI
                     DEITFNDCLKFDEITKLDLFDNYDFLSLNTFELRDGEAVIEEVNMYLSDNFILVVVNE
                     EHFLFEFVKNIILKNSQLEKNPVINLFKINYLILREVIKNGFESLEKVEELILQIEDE
                     MMDNINKNHVSRISDVRGLTRIIVKNTRPLLYIGDRIVKENIRYLKYSNVKKYNLENF
                     QGIDFGIDKLYNFALSTRELADKLLDIYSSRVGEKTNNLITKLTLLTAISAPLTIITG
                     IYGMNFRYMPELNWIYGYPATLFFMLCIIFVGIIIFKIKKLL"
     gene            16814..16969
                     /locus_tag="KR231_002345"
     CDS             16814..16969
                     /locus_tag="KR231_002345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0004712.1"
                     /translation="MKGILKELTAKLYSFFYFMFWGFYFSAGYFFYKNICTSFLVRPY
                     FSDFEHK"
     gene            17099..18112
                     /gene="aroF"
                     /locus_tag="KR231_002346"
     CDS             17099..18112
                     /gene="aroF"
                     /locus_tag="KR231_002346"
                     /EC_number="2.5.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003452924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-7-phosphoheptulonate synthase"
                     /protein_id="HBH0004713.1"
                     /translation="MIVVLKMGADKNEVKKLIEAIGREGVEVNPIDGTELTVLGLVGD
                     TSKIDAKRIEANKVVEKVMHVVEPFKKANRKFHPEPSIINVNGMEIGSKKIAMIAGPC
                     SVETEDQIVSIAKDVKKSGAGFLRGGAFKPRTSPYAFQGLKYDGLDLLKKAKEKTGLP
                     IVTEIMSTQDIDIFEENVDVIQVGARNMQNFDLLKELGKTNKTILLKRGLSATIEEWL
                     MSAEYIMAGGNENVVLCERGIRTFETYTRNTLDLSAILAVKKLSHLPVIVDPSHAAGK
                     SWMVDSLSKAAIAVGADGLIIEVHNDPAHALCDGKQSIKPNEYDELISELKTIASAVG
                     REI"
     gene            18134..19198
                     /locus_tag="KR231_002347"
     CDS             18134..19198
                     /locus_tag="KR231_002347"
                     /EC_number="4.2.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-dehydroquinate synthase"
                     /protein_id="HBH0004714.1"
                     /translation="MEEKLLVNLKENSYNIFIKKNILKNIGEEIKKIYFGNKIFIVTD
                     ENIAKLYLDKVKNNLSESGFEIKSLILKSGEETKSFNTLPKIYDSLLDFKLTRKDLII
                     TLGGGVIGDLGGFAAATFLRGISFIQIPTSLLAQVDSSVGGKVGVDLERGKNLVGSFY
                     QPKAVFIDPNVLLSLPEKFYRDGMAEVIKYGCIKDKTFFNKLLSLKNREEVMQHIEYI
                     IHKCCFIKKTVVEADEKDFGDRMLLNFGHTLGHAIEKYYNFTGYTHGEAVAIGMYKIT
                     LESEKIGITKKGTSELIKSILMNYNLPYEIELRDNKSIVDAISLDKKNLGDTLKIILL
                     KDIGESIIYNTTSKFFQEVR"
     gene            19198..20511
                     /gene="aroA"
                     /locus_tag="KR231_002348"
     CDS             19198..20511
                     /gene="aroA"
                     /locus_tag="KR231_002348"
                     /EC_number="2.5.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-phosphoshikimate 1-carboxyvinyltransferase"
                     /protein_id="HBH0004715.1"
                     /translation="MGSLKIYPSKLSGDVKIPPSKSMAHRAVICSSLSNGKSRISNID
                     FSDDIIATIRAMTSLGAIIEKKEDILEISGIFSKEGILNRENQLNQPKLTIDCNESGS
                     TLRFLVPISLAFDGVKRFIGRGNLGKRPLDTYYEIFDRQNIKYSYKENQLDLIISGKL
                     KPDEFRVKGNISSQFITGLLFILPTLESDSKIIITTELESKGYLDLTLSTIKDFGVEI
                     INNNYKEFIIKGNQTYKARDYKVEGDYSQGAFYLSADAIGEDISILDLKEDSLQGDSE
                     VVEILSRMGMEILREGNKIKGITNGLNGTLIDASQCPDIIPVLSVVASLSIGRTTIIN
                     AGRLRIKECDRLHAINVELNKLGANIEEKEDSLIIEGVSKLNGGVEVWSHKDHRIAMT
                     LAIASCRCDKPIILKDFECVSKSYPHFFKDFKMLGGRIDEWNMGK"
     gene            20489..21568
                     /gene="aroC"
                     /locus_tag="KR231_002349"
     CDS             20489..21568
                     /gene="aroC"
                     /locus_tag="KR231_002349"
                     /EC_number="4.2.3.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate synthase"
                     /protein_id="HBH0004716.1"
                     /translation="MSGIWGNNLKVSIFGESHGNAIGINIDGLPSGIELDLDNIDKEM
                     KRRAPGKNSISTSRNESDIPEILSGYFNGRTTGTPLCAIIRNSDTRSKDYGELKNLMR
                     PGHADFTGNVRYSGFNDYRGGGHFSGRITAPLVFCGAICKQILSQKGIEIGAHIKKIK
                     NIEDMSFDYVNISKQQLSNLQTLELPLLDLSKEEAMKNTIIDAKNQGDSVGGIIECAV
                     VGINVGLGNPFFDSVESTLSHLLFSVPAVKGVEFGLGFELADMYGSQSNDEMYYEGNQ
                     VKSKTNNNGGIIGGITTGMPIIFKVAIKPTPSISRQQNTVNIKDKKDDILYIKGRHDP
                     CIVQRAIPVIEAVTAIGIFDLMKGR"
     gene            21571..22767
                     /gene="pheA"
                     /locus_tag="KR231_002350"
     CDS             21571..22767
                     /gene="pheA"
                     /locus_tag="KR231_002350"
                     /EC_number="4.2.1.51"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428637.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydratase"
                     /protein_id="HBH0004717.1"
                     /translation="MEDLTRYRNEIDNIDKELIQLFEKRMNTVLEIARHKMKNNTTIL
                     QKDREEKVLSRAVDNLDNKAYSQETVQFFNSIMEISRGLQKRFIDNDGEQKIEFSLDS
                     SNKNFDLSNVNKYKSLKDELNKKNILVGFPGKSGSFTEEALNKFFNKKISKKQFKEFE
                     DVFIALKNKEINYGIIPIENSSTGAISETYDLLRKYGFYIVGEECIKIDQNLIGIKDT
                     KLEDIKEIYSHPQGIGQCSEFLKQNSTWKLIPFNNTATSAELVRKLQDKTKAAIASKK
                     AASIYGLEIISPCINDIANNYTRFVVISNQIHIEEESNKMSVVFSVEHEAGKLYKVLG
                     YFAKNNINMTKIESRPMKNASWRYFFYIDFECSIYNAKVYDLLELIEHNTAYFKFMGV
                     YKNKTE"
     gene            22814..23623
                     /gene="aroE"
                     /locus_tag="KR231_002351"
     CDS             22814..23623
                     /gene="aroE"
                     /locus_tag="KR231_002351"
                     /EC_number="1.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate dehydrogenase"
                     /protein_id="HBH0004718.1"
                     /translation="MNFFGLVGEKLSHSVSPQIHKRVFEILNIESAYKNFEISKEDIS
                     KLDGAIKLLGIQGVNVTVPYKERIMKYLDFISPEAKRIGAVNTILLRENMLYGYNTDY
                     FGLDSMFKMANIDVQGKVAVILGTGGASKAALTYFIDSGIEKLYVSTRKKDDKKLLNS
                     KAILIDYEELKHIKGDIILNATPVGMYPNVGISPVSKSIIQNFDILIDLIYNPGETEF
                     LRIGNSMGKKTCDGLYMLVGQAIKSQEIWQDTKIDNSILDVIYNELKLEFL"
     gene            23635..24168
                     /locus_tag="KR231_002352"
     CDS             23635..24168
                     /locus_tag="KR231_002352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate kinase"
                     /protein_id="HBH0004719.1"
                     /translation="MINKTKEKLILIGMPGSGKTTIGKLLAKEYNCSFCDMDDYIIQI
                     SQKSIAELFSEGEDIFRNYETQACRELSISDKTVISTGGGVIKKDINMEILKETGIII
                     FIDRPIQKILEDININSRPLLKNGKDRLYNLYNERINLYKKFSDIEILNDKSLNNAVY
                     NITNAVSENFKFDFKEK"
     gene            24189..25028
                     /locus_tag="KR231_002353"
     CDS             24189..25028
                     /locus_tag="KR231_002353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydrogenase"
                     /protein_id="HBH0004720.1"
                     /translation="MNIVIVGLGVIGGSFAKALKKAGYENVFGVDVDLETLKKAEKAK
                     IIKKGCTTGKELFKKADLIILSIYPRLVVDFLNNNKNFFKKGTIITDTTGIKETLIND
                     VLQIIPDDIDFIFGHPMAGREKKGIDFASEQVFNGANYIITPTGRNNIKNLELVENLI
                     LEIGFKRVKKLTSQKHDEIIAFTSQLPHVMAVALINSDEEGRDTGKFIGDSYRDLTRI
                     ANMNEDLWSELFLGNRDNLLKVIENFESEVNLVKEAIFNNDKNKLIEYFKKSSIRREA
                     LEK"
     gene            25296..26777
                     /locus_tag="KR231_002354"
     CDS             25296..26777
                     /locus_tag="KR231_002354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional diguanylate
                     cyclase/phosphodiesterase"
                     /protein_id="HBH0004721.1"
                     /translation="MKKNRLIAKNISIAFIVLFFFSVFTFFYVGNINRVLEYETNDII
                     TVTIAGWIILSFLFLGIIIYILYSKANSQKTIEKVAYTDFVTGYSNWRKFELDVTNLL
                     KKTSQNNKYAMVIFDIDKFKAINDIYGHKKGNLILKDIADTLNELTDINETFARVSAD
                     NFNILLTYNKKEDIINIIKKIMANNELVNLSFGIYEIKDKDLSVSVYSDRASLAKSSI
                     KNNSDVNFAFFNDKLREKLLFEDKIEKEMEYALESGQFVMYLQPKYNIKLDKFCGSEA
                     LVRWQYTEKEVIYPGDFIPIFEKNGFIRKIDMYILEQACKEIRSLFDKGISPLPISVN
                     FSRVDFFKKDFIENIVNICDRYKIPYSLIEIEITESSMFGDTDTLFNVSRNLQDIGFI
                     VAMDDFGSGYSSVNMLKNIPLNVIKLDRGFFVYDKDVDKSQIVIKSIVSLIKQLGIRV
                     VAEGIETRSQIEMLKKANCDIVQGYYFSKPLPIKEFEKLVYKI"
     gene            26810..30247
                     /locus_tag="KR231_002355"
     CDS             26810..30247
                     /locus_tag="KR231_002355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PAS domain-containing protein"
                     /protein_id="HBH0004722.1"
                     /translation="MIRAKSLKNVLSIVLIFLFTIISFSDFAFKTNVQEEENSKINLR
                     EISLQSSNAIKIKLDSSLSFIKSVANMVSYFNTIDNSKIVPLLANISKESDFQRISIV
                     SPDGISHTSDGKIINVSKYQYFKKAIKGESNISEVVKSPIDGKDTFVIATPVFNKNNK
                     IIGVLYGSYYNDKLAEFIDITSFNSEGYIDIFESSGQFVLKSSHTNKLIKSSSNIYDI
                     FKKASFDDGYSYKKIYEDTKNNKSGFTSYEYKGENRYATYTPIGVNDWYVISVIPQYT
                     VRRNIDKINQLAFSLIFKVFLLFIMLITYIIYKNNKSQKDILKANKEISSITNSIPGG
                     VQKCTLGETCNINFLSDGFIELFGYTREEIKTLFNNDFYSLIHKDDVERIKKEIFKQL
                     YKNKTVELEYRIITKNGNTVWVLDKGELITEPDGKEYFCCVTVDITRTKQLEQEMEQK
                     NLELEMISENVLGGIIITEFNDDFTIKYANSGYLSMIGYTREQLENELKYKACNLVFY
                     EDRKKALESIQHQLNTKGIAVYQHRIRRRDGNIIWVSIKGRLIVDDDGIEKGIWILND
                     ITDLKNAEQKLKINEERFRIALKQTSNTIFEYDIKTKSLLNTSKELDKYNIYKITKNV
                     PYSLVELGVIHKDFSDDFINMYENVINGAKKASCVVKMKLPDENYIWNKVTLTTIFDE
                     DGNPVRAIGIQEDISKQKEAEIRYNQEGKYHSAILSEAMITYEINVSKDTFIKGNESW
                     QKPFGIKPDNNYSQMVKTIANSIVHKDNKETFLNTFLCENLLDAYKNNVTEIKLEYRR
                     MNQENKMIWVICTMHLIKDSITNDIKALAYVKDIDKQKNEEIRLKLKAERDTLTGLYN
                     KGTTEKLINDFLNSEEASLGMHAFLIVDIDNFKSVNDNLGHVFGDKVLFEVSKNLKPI
                     FRKDDIVGRIGGDEFIVFLKNIQSFENIKKKAEKICDIFRNSYTENKKTYKISGTVGI
                     SFVPEHGTVFEELYKKADIALYYAKSKGKDKYALYNDCIYQNELENNISDNNIKLADK
                     CEKSKPVLKEILDSIDNYIYIVNPNTYELLFVNNKVSRLDLEIKLGETCYKSLLKSDR
                     PCNNCPLNGLEENKHSKFKIETNTFGKNISIASWINCIDGEYNCLIECIDSSLYKNK"
     gene            30265..31011
                     /locus_tag="KR231_002356"
     CDS             30265..31011
                     /locus_tag="KR231_002356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889797.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcF family protein"
                     /protein_id="HBH0004723.1"
                     /translation="MLNSITLILGIIFTIYYFYLKIVFGGISFSEIFLVVGIVLIIYQ
                     IFKKKIKEKKVFYRVLKIIISIFLIVFVVTESLIIFYPKNSLESKSDYLLILGASVKK
                     TTPSTTLKGRLDTALKYLKINDNCYVVVSGGKGSGEKITEAKAMKDYLIKNGIDKNRI
                     IEEDKSTNTYENFKYSKLKIEEHSQRKLSDLKVKIVTTDFHVLRSKILAYRNGYKNTS
                     FYASKSKLSFVPTYYTREFFALWKTIIFDR"
BASE COUNT        12577 a         3287 c         5447 g         9855 t
ORIGIN      
        1 aaacaaactt gctaaattac aaagagaatt atcgagaaaa acaatcggta gtttaaatag
       61 aaataaagca agattaaaag ttgcaagatt tcaagaacat atagctaatc aaagaaagga
      121 ttttctacaa aaattatcta ctaaattaat aaaagagaat gatattattt gcatagaaga
      181 tttacaagta aagaatatga ttagaaatcg taaactatct cgcttaattt ctgatgtgtc
      241 atggtcagag tttattcgtc aattagaata caaggctaat tggcatggta gacaaattgt
      301 aaaggtaggt aaattctttg caagttcaca aatatgcaat aaatgtgggt ataaaaacga
      361 ggaagtgaag gacttaaata taagagaatg gatttgtcct agttgtaatg aaactcacga
      421 tagagatata aatgcaagta taaatatatt aaaagaagga ttaagactaa taacaattca
      481 aaataaataa cgtatgtaag aaccgtagga actacgggga tagcctgtgg agaattagta
      541 agacatattt tagtatgcaa aattctgtga agcaggaacc ctgtgacttt agtcatggga
      601 ggttcagtgt agcaataaat atatatcacc tggctttatt gatgcacata tgcatattga
      661 atctacaatg gtaatgccaa ttgaattatc gaaaaaatta ttaaaatcag gtacgacaac
      721 tatcatagcc gacccacatg agttggtcaa tgtaaaagga gttagtgcaa tagatttttt
      781 attagaatcg acaaaagata taccacttaa tgtatatatt atggtgcctt catccgtacc
      841 tgcaacaagt tttgaaacta atggagttgg taaatttagt gcaaaagaca tggagagtta
      901 tgtaaataat cctagaattt taggtttagg agaggtaatg tgttttaatg atgttataaa
      961 ttctgaaaat gaaatcttgg ataaactaga gctttttaaa aataaagttg tagatggaca
     1021 tgcacctaat ataaatggta aatcacttca gacatatgta tgtgcaggaa tagaaaatga
     1081 ccatgaatgt ataacttttg atgaagtata tgaaaaattg agagcaggat taaaaatttt
     1141 aataagagaa ggaagcgcag caaaaaattt aaagtctata gtaagtggta tgctaaagca
     1201 taacttgcca attgaagaat ttatgttttg cacagatgat aagcacttag atgatataga
     1261 aaaacaaggt cacataagat ggaatataaa atgtgcgatt gatttaggta tggaacctgt
     1321 tagggctata aaagttgcaa cttataattc tgcaaaagca tatgggttaa ggaaaattgg
     1381 agcaataggt gcgggttata aggcagatat tgttgtattg aatgatttag acaaaatgga
     1441 agtggatagt gtatataaag atggtaattt ggtaaacgaa gagatgtttt ctaattacaa
     1501 ttatgagatt aaagataaag aattgcttaa tacagtcaag tttaaatata ttaataaaga
     1561 aaaaatacag ttaaaagtaa gtgaaaaaaa ttatgtaatg gagattgtac cttatcaaat
     1621 tttgacaaat aaggtatatg aatctttacc atgtgcagat ggatattttg ttccaaataa
     1681 agagtattca aaactttgtg ttgttgagag acatagaatg actggaaatg tagcagttgc
     1741 tccactaaaa ggatttggca taaaaaatgg agcaattgct actactgtgg cccatgattc
     1801 tcataatatt atagttgcag gggataatga tgatgatatt ctagtagcta taaattactt
     1861 aaaggaaata caaggtggtt atgtaattgt atcaaatgga aaagttcttg cacacctaag
     1921 tcttcaagta gctggattaa ttagtacttt tacagctgaa gaagtacaag aaattactga
     1981 taatatgttg gagatagcaa gaaaaatggg agttccagag tatgtagacc cttttattac
     2041 actttctttt atggcacttc cagttgttcc acaaataaga cttacagatt taggtctatt
     2101 tgatgttgag gaatttaaat ttatatagat aatataaaag taataataaa tgaggctttc
     2161 tcaaaatagg gataagtctc tttttattgt tgaaatgata aaaatatatt tgatttcata
     2221 caaaaaagag catctcatga actaaaaatt ttatttttag atatccttat tttaattaat
     2281 ctatcattta accttgtttt aagcatagat atcttaataa aactattttc agtctatttt
     2341 aacatataaa tacatgaaaa ttatatattt atgaaacttt atacataaaa aataaaatat
     2401 tttatttata tatagattta tagggtaata atataagcat agtataaaat tattaataaa
     2461 aacaaaagga gagatattta tgttgagtat aggaacaaaa gcaccagaat ttacactaga
     2521 agataaagat ggaaataagg taagtatgtc agattttaaa ggcaaaaaag tagtagtata
     2581 tttttatcct aaagataata caccaggatg tacacgtcaa gcttgtgctt ttagaaatgc
     2641 atatgatgga tttaaaaagg aagatataca agttattggg ataagtaaag atagtataaa
     2701 atcacatcaa aaatttgcag aaaagcatga acttcctttt attttacttt ctgaccctga
     2761 cttagttgct ataaaagctt ttgatgtatg gaaagagaaa aaaatgtatg gaaaaactgc
     2821 attgggagtt gtacgtgcga catatattat agatgaaaat ggaattattg aaaaagtctt
     2881 tgaaaaagca aaaccagaca caaatgcaca agagattctt gaatatttgg aaaaacagga
     2941 gtaataagaa tttatgatta taatgttatc accagctaaa aatatgaaga atatagaagt
     3001 atttgataga gatttgagtt tgccttgctt tatagataac acaaaagaaa tagtggaaaa
     3061 tataaagaca tttggtatag aagattttaa aaataaaatg aaaattaatg aaaaattagc
     3121 tgtattaaat aaaaatagat ttgaaagcat taaatttgat agattaggaa accctgcaat
     3181 cttaacttat gatggaatac aatataaaaa tatagaagca gaaaatttta caaggaaaga
     3241 tgaagagttt gcaaatagct gtattcgaat cataagtgga ttgtatggtg ttgtaaaacc
     3301 atatgatagt atatatgaat atagattaga aatgcagaca aaattacgag taggtgagtt
     3361 taagaattta tacgaatatt ggggaaatcg tatatataaa gaactaatca aagaaaaaac
     3421 agctatcgtt aatctttcat caaatgaata cagcaaatcc atagaaaaat ttattaaaga
     3481 tagtgataca tatattacat gtacttttaa agtaaataaa aatggcatat taaaagtgga
     3541 atctacacaa gcaaagaaag ctagaggtat gatgacaaaa tacattgtaa aaaataggat
     3601 aagagatatt gaagaactga aaaagtttaa tttagaaggt tataagtata aagaaaactt
     3661 atctaacaat agtgaataca tatttgtaaa agagtagaag ttttgttaaa tattaaatgg
     3721 cattgttaaa tttaggtaaa atatacttag tgtgtattga attgaacttg attttaaaat
     3781 ataattattc ttaaattaaa aaaagaaagg agtggtcttc caaaatggaa aatcacaaac
     3841 agatgccttg gcattcaaga gcaacgcatg aaattttaga aagtctagat tcatcagagg
     3901 aggggctcac cgataccgag gcggaaaaac ggcttaaaga gaatggctta aatgaactta
     3961 gaaaaaaacc acctagaaca actttacaaa tgctttggag tcaaattaca gatgctatgg
     4021 ttatgatact aataggagca gcaatattat ctttgatatt tggcgaattt acagaagctt
     4081 ttgtaatact aataattgta acagtaaatg cagttattgg aattgttcaa gagaaaaaag
     4141 cagaatcatc attagaagca ttaaaaaata tgaactcacc tacagctcgt gttatgcgtg
     4201 atggtgaaga aaatgttatt ccagcaagta atcttgtagt aggagatatt gtttttttag
     4261 aagatggagc tatggttcca gcagaccttc gtttaataga aacatcaagt ttaaaaattc
     4321 aagaggcttc tttaacagga gaatctgttc catcagaaaa agatgcagat acaatcttac
     4381 ctaaagaatg tgtattagga gaccgtagca atatggcgta tacatcttca atagtcacat
     4441 atggtagagg tgtaggtgtt gtagtagcaa ctggtatgga tacagaagtg ggtaacatag
     4501 cacatctttt agattcacaa gatgattttg atactcctat aaaacgtaaa cttaatactg
     4561 ttggaaagac attaagtgtc ataggtatta ttgtatgcgt tgttatattt gcaataggtg
     4621 cattttatca gagacctctc ttgccaatgt ttatgattgc aatttccctt gccatatcaa
     4681 ttattccaga gggattacct gcaacagcta ctattgtaat ggctttaggc gtacagcgta
     4741 tggctaaaag aaatgcttta attagaaaat tacctgctgt tgaaacatta ggaggagcta
     4801 cagtaatatg ttgtgataaa actggtacgt taaccttaaa taaaatgact gttacacata
     4861 ttgctgtcaa tggagatttt gaatctggaa aagtgacatc aatagatact gcatctgaaa
     4921 aacatccatt agtgtataaa gagattgttt atgctggtgc actttgtaat gatgcatgta
     4981 ttaatccaga taaaacagat gaaatattag gtgacccaac agagggcgca ttaattttta
     5041 tggccaaaaa atttggaata gatcaagaag ctcttgaaga agaatatcca cgtgtatttg
     5101 aacagccttt tgattcagat agaaaatgta tgacaactgt tcataatata gatgaaaaga
     5161 ttattgctta tactaaagga gcagtagacg aaattcttga cctatgtact aaaatattaa
     5221 cttcaaaagg tgaaagaaac attaccgaag tggataaaaa gaatatacac gaattatgtc
     5281 ttaacatgtc taaagatgca ttgcgtgtac ttggttttgc taagcgtgag atttcatcta
     5341 taccaaaaga agatagtgaa aatatagaat atgatttaac atttataggt atggttggta
     5401 tgattgaccc accaagaact gaggtaattg atgcagtaag tacttgtaaa gaagcaggta
     5461 taagaaccat aatgataaca ggtgaccata aagttactgc cacaacaatc gctcatgagt
     5521 taggaatatg gagtgaagaa aatactgtga tatctggtga tgaacttgat aatttgagtg
     5581 atgatgaact agatgaagct gttaaaaata ctacagtatt tgctcgtgta tccccatttg
     5641 ataaacttag aattatacaa tctctaaaaa gaattggaga agtaccagca atgactgggg
     5701 atggtgtaaa tgactctcct gccttaaagt ctgctgatat tggtatagcc atgggtataa
     5761 gtggtacaga tgttgcaaaa gattcttctg acatgatttt aatggacgat agttttacaa
     5821 caattgctta tgcaataaaa gaaggtagac gtgtatatag aaacatacaa aaagttatac
     5881 aatttttgct tgttggtaat atagcagaga tacttacgtt gtttgtagca atattattaa
     5941 attgggatac tccgcttctt gctgttcata ttctatgggt aaaccttgca actgctacgc
     6001 ttccagccct tgctcttgga gttgacccac caagcagaaa tataatgaag caccagccag
     6061 tgaaatcaac cactttgttt gaaaaaaatc ttatacaaag agttgttacc caaggtatat
     6121 ttgtggcaat aatgactatt ttagcatata aaattggtct taatatagaa aatcattctg
     6181 taggtcaaac aatggcattt tgtgtattag cattttcaca gatgttacga gcatttagtc
     6241 agcgttcaaa tacagattca atgtttaata gaaataatgg taaaaatcca tttcttttaa
     6301 tctcattttt aacttctgca tttttaatag cagtaatact atttgcacct gtttttagaa
     6361 atgcttttaa cttaacagtt ttaaataact tagagtggct tataacgatt gttttagcca
     6421 taatgtctgt aattcaagta gaggttggga aaattattaa aagaaaaaaa ttaaaaaaat
     6481 agttgacaaa attaggaaaa atatataaga tataaaacat agaaaaatta aataaatctt
     6541 atccagagag gtggagggac tggccctatg aaacccggca accagtatat ttatatacag
     6601 tggtgctaaa tcctgcggcg aaagctgaga gatgagtata attaagctta tacagagcct
     6661 gagttatata ctcaggcttt atttatttta actctcatct ggtaaatagt ttaatttttt
     6721 ttactaaaat ctaaggggga tacaagaatg tataataaag aaacaatatg tgtgcaagga
     6781 aattataaac caggtaatgg agaaccaaga gtactacctt tatatcaaag tacaactttt
     6841 aaatatagca gtatagacca acttgctgaa ttatttgatt taaaagttga tggacatata
     6901 tattcaagaa taagcaatcc tactattcaa gcttttgaag aaaaaataag tttactagag
     6961 ggtggagtat cttctgtagc tgtatcatca gggcaatctg caaatatgtt ggcagtttta
     7021 aatatatgta aatcaggaga tagtatactt tgttcttcaa aagtatatgg aggaacattc
     7081 aatttactag gacctagtct taaaaaattt ggtatagatt taatatcgtt tgacttagat
     7141 tcaagtgaag atgagatagt agaacttgca aaggaaaata ctaaggttgt gtttgcagaa
     7201 acacttgcaa atccaactct tgaagtcata gattttgaaa aaatagcaaa tgtagctaag
     7261 agaattaatg ttccatttat tgttgataat tcattagcat ctccagtgct ttgtaaccct
     7321 ttaaagtatg gagcaaatat agttactcat tctaccacaa aatatttaga tgggcatgct
     7381 tcaagtgttg gaggaattat agtggatggt ggaaacttta actgggataa tggaaaattt
     7441 ccagaattag ttgagccaga cccaacatat catggtataa gctatactca aaaatttgga
     7501 aatgccgcat atgcaactaa agcaagagtt cagttgctta gagactatgg aaattgttta
     7561 agcccattca atgcgtatct tactaattta aatgttgaaa cactacatct tagaatggag
     7621 agacatagtg aaaatgcact taaaatagct agatttttag aaaaacatga aaatgtagat
     7681 tggattaatt acccaggact tgaagataac aagtattatg agaatgccaa aaagtattta
     7741 tcaagaggat gtagtggtgt tttatcattt ggagtaagag gtgggttaga aaatgccaaa
     7801 aaatttgtgg aaaaattaca gatagcatct ttggttacac atgtttcaga tgtaagaact
     7861 tgtgttatac atccagcttc aactactcat agacaattaa cagaggaaca attaattgca
     7921 tctggagtat tgccttcact aataagatta tctgttggaa tagaaaatgt agaggattta
     7981 atagctgatt taaatcaagc tttaaatttc taatattcta agagaaagag aagtgaaaag
     8041 atatggcttt aatactacca aagggattac ctgttattaa taaattatta gatgaaggaa
     8101 tagatgtaat ttataaagaa gattttaaaa aggaattaaa gtatgaagaa aacatagaca
     8161 ctaagatagc tatactaaat ctaatgccta taaagataga tacagaatta gatttactaa
     8221 gaaggataga taaaacagga ttcaacgtgt ctgtggaatt tattaaaatt tcaacaagag
     8281 aaagtaaaag aagttgtaat gaatatgtta aagaatttta taaaacattt gatgaagcca
     8341 aaggagagta ttttgatggc tttataataa caggagctcc agttgaacaa atggagtttg
     8401 aagaagttga ttattggaat gaactagaag aaattatgga ttattctaag agaaaaacta
     8461 aatctacatt atatatatgt tgggcagctc aagcaagtct ttacaaatac tacaatgtaa
     8521 aaaaacttcc actaagtcaa aaatgttttg gagtatttaa gcataaggta gataaagata
     8581 gtaaaatagt agatggattt gaaaatgaat tttttgctcc acattcaaga catactactg
     8641 taaatattga agctttgaaa gagaataaag agttgagcat tgtgagtcat tctaaagaag
     8701 ctggtcccta tataattaca aattcaagag atgtgttcgt aatgggtcat agcgagtatg
     8761 acaaatacac tcttgataaa gaatataaga gggatataaa taaaggagat aaaatatcta
     8821 tacctcaaaa ttactatatt aatgatgacc cttcagaaga gccaactgta aaatggaaaa
     8881 aacattcaga attgttgttt agaaattgga taaaaaacta tttgatacaa taaattttaa
     8941 gagtatataa atgttaacta aaaaaatata gaaatttata ggtataaagt taatcttaat
     9001 gatactttat accttatttt tttaaaattt gaccttataa tagtagtttt atattttaag
     9061 aaaatcactt taggtgtatg tagatagagg tggctttaat tttatatatg gtgcgataat
     9121 gggagactaa acctttatag tatcaataaa tttgtatttt aacttttaaa agagattaaa
     9181 aagggagaaa tcagtgtaaa atatatatag attttttatt aaattttatt aaaaatatcc
     9241 tgtataaaat taaatatcaa taagataaca aaatttcaat tgaagttaca atattgtaat
     9301 tgacaataaa tacttaatac tataatattt aatacattaa acattatagt gttaagtatt
     9361 tattacagta tgcacttcag cctaaatttg aaataaagta ttttcgtagg gagcgtttgt
     9421 atggatgaga tgagttttaa gaaagagcta ctagagttga ctagagatat aaatatgaaa
     9481 tttacaactt tattaagtga tttttatcag ccacttggta ttacagcagt gcaagctttg
     9541 attttatctg agttatgtga acatggagag aaaaaaataa gcgatttagg gaagaactta
     9601 aacatgacaa atagtaatgt atcagtaatc tgtcaaaggc ttgaaaaaaa tggcttttta
     9661 aatcgcataa gagatataga agaccaacga attgtaaaag taaaagttac aaataaatca
     9721 ttggatatac aagaacatat ttcaagtagt atttttgata gttattttga aaatatgacc
     9781 agtgaaaaat tgcaagatat ggaagatata atagaaggtt tagagaaatt aaataaactt
     9841 ttaacttaca ttgattgcaa ataacataaa aataatttaa aggagaataa aattatggat
     9901 gaacataaac cccaaaaaag gtcagcactc tattattata cagttataat aatagtagta
     9961 atgtttttaa atgctttaat atttccaagt ttaatggata aaaaaatggt tgagattgac
    10021 tatggaaagt ttctcacaat gttggataca ggaaaggtta aatctgttga gatagaaaat
    10081 aatagaatag caataaatcc atctagtagc aaggataaga atatatacat aactggtaga
    10141 atggatgacc cagaattggt agatagacta aaaaatgcaa aagtagaatt tactaaggtt
    10201 attcctaagg aaaattcacc tcttttaagt attttactta catggataat acctataggt
    10261 attcttatgc tatttggtaa cttaatgatg aagtctatgc aaaagcgaat gggtggtaat
    10321 gctatgcaat ttggaaaaag caacgccaaa atgtatgtat ctgctcaaag tggaaaaaga
    10381 tttaatgatg tagctggtca agatgaggca aaagaagctt taactgaaat agtagatttc
    10441 ttacacaatc cagaaaagta taaaaagata ggagcacaaa tgcctaaagg agcactttta
    10501 gtaggacctc caggtacagg aaaaacactc cttgcaaaag ctgtagcagg tgaagcaaat
    10561 gtaccatttt tctcaatatc tggttctgag tttgttgaga tgtttgtagg aatgggagct
    10621 tctaggattc gtgatttatt taaacaagca aaagaaaaag ctccatgtat agtgtttata
    10681 gatgagattg atactattgg taaaaagcgt gataatggaa gtggattagg tggaaatgat
    10741 gaacgtgaac aaactttaaa tcagttgtta agtgagatgg atggttttga tggtggaatt
    10801 ggagtagtaa tacttgctgc tacaaataga cctgacagtc ttgacaaagc attacttcgt
    10861 ccaggaagat ttgatagacg tataccagtt gaacttccag accttggagg acgtgaagct
    10921 atattaaagg tacatgctca aaatgtaaat gtaagctcag atatagatta taatgcaatt
    10981 gcaaggtcta catcaggagc atcaggtgca gaacttgcaa atattgtaaa cgaagcagca
    11041 cttttagcag ttaagtctgg cagagatata gtagaacaac aggattttga tgaatctgtt
    11101 gaaactgtaa ttgctgggta tcaacgtaaa ggagctgtaa tttcagataa ggaaaagaaa
    11161 attatagcat atcatgaaat aggtcatgca cttgttgctg ctatgcaaaa acattctgca
    11221 cctgtccata agattactat aatacctaga acttcaggag cattgggata tactatgcaa
    11281 gttgctgaag atgagagtgt acttatgtct aaagaagaag caattgataa aataactact
    11341 tttacaggtg gtcgtgctgc tgaagaggtt atctttaaca cttgtacatc aggagcatca
    11401 aatgatatag aacaagctac taaaattgca agagctatgg ttactcgcct tggtatgagt
    11461 gaagagtttg atatggtcgc tcttgaaact gtaagcaatc aatatttagg aggagatact
    11521 tctcttgctt gttcttccga cactgctgct aaaatagatg aagaggtatt taaaatagta
    11581 aaggcttgtc acaaaaatgc aattgaaatc ttagaaaata atattgataa attgcatgaa
    11641 cttgctaatt atttattaga aaaagaaact attacaggtg atgagtttat ggaaatactt
    11701 aacttaaact aaaatgatta tacacaagat aaaaatgcct attgttaggc atttttattt
    11761 tacaactaaa ttttttaaat tcatatttaa atctttacat aatcttaatc attaaaaata
    11821 catcttaact acaattttat atcggaattg atattataat agtaatgaat ggtgtaagga
    11881 ggttttttaa tggatagacc taatcctgat attctattag aaaaaattaa aaatgaagaa
    11941 gaaaaactaa gtagaggtca attaaaaata ttctttggtt atgcagctgg agtaggaaaa
    12001 acctactcta tgttggaatc tgcacaaaat ttaaaaaaag tgggtgtaga tgtagtagtt
    12061 ggatatattg aaccacacac tagaccagaa acattggctt tacttgatgg cttggaaatt
    12121 cttcctgtaa aggagataga atataaatct ataaaactaa aagaatttga tttagatgct
    12181 gctttagcaa gaaaaccaga agttatatta gtagatgaat ttgcccattc taatgttgct
    12241 gggttaaggc atacaaaaag atggcaagat atagaagaat tgctgttagc aggcataaat
    12301 gtctacacta ctgtaaatgt acaacattta gaaagtctaa atgacattgt tgagataatt
    12361 acaaacgtat cagttaaaga gactatacca gataagtttt tggatacaaa tacacagtta
    12421 gaacttatag atgttgaacc tgatgtactt cttgaaaggt tcaatgaagg taagatatat
    12481 aagaaagaac aagctactag agcaaaaaat aattttttta taaaagataa cctggttgca
    12541 cttagagaaa tcgcacttag aaaaactgca gagagagtta ataaagaagt tcaaatgacc
    12601 agactatcaa agggtgatgt aactgtaata cctacatcag atacacttct tgcatgtata
    12661 agtccatctc catcttcagc aaaagttatt agaactgcat ccagaatatc agacagtaca
    12721 tttgcaaaat ggatagcttt atatgttgaa actccaaaca cagcaagact tccatttgat
    12781 gaacaaaaac aactacaaaa taacctaaaa ttagctaaga aattaggtgg agaaataatt
    12841 gttttacatg gtgaaaatat aatagagcaa atacttagaa ttgcaaagct gagaaatgta
    12901 acaaaaattg taataggtag aaatcattca agtaataaaa gatttagtaa aagatttaaa
    12961 aaagatatag ttgacaaatt aattgatgaa gttgattata tagatataca tataattcca
    13021 tataaatttg cctcagatgt taaatacaaa cctaaaaagg ataaatcatc aataaaatct
    13081 aaatttaaaa ttagcaaagt tgattttata aaacttatat ttattacttt gatgataagt
    13141 attttagcat atgcagtaca aagcatggga tttataagag aaaatatatt gttaatatat
    13201 atgttgggtg tagttttagt ttctatgtgg actaaagggt atagtacagg tataataagt
    13261 tctgtattta atatagttct tttaaattat tttttcacag caccattata tacattatct
    13321 atagcagatt caaactatat agtaacactg gttgtattct caatagtagg tataataact
    13381 agcactctta cgtctaagat acagcatgaa gcagaaactg ctgctaaaag agaagaaaat
    13441 acaaaaatga tatatcaaat aattaaggga tttttaagat tatcaaataa agatgatata
    13501 gtaaacaaag gtatagaact tttgtctctt agcttaagta gagatgtaat ttgttattta
    13561 aatgtagata agcataataa atcaaagctt tacaaaaaaa atactaataa taaggataaa
    13621 aatgatttgg atagtgaaga tgaaaaagct gttgcaagtt gggttttatc caattcaaca
    13681 gtagcaggaa atgacacgga tacacttcct ggttcaaagg gatactatat accaattgta
    13741 ggaatgaatt taactttagg agtagtggga atatcatgta ttgattcaaa attggataca
    13801 gaagatataa gcttaattga aacaataatt gctcaaatgg caatagcgct tgatagagaa
    13861 atcttgtcag aagctaaaga aaataccaat cttgagattg aaagggaaag attaagaagt
    13921 aatcttttaa gagcagtttc gcatgacctt agaactccac tagcaggaat atctggtgca
    13981 gtaagtacaa ttataaaaaa caagggtact ataggtcaag atataataga tgaattactt
    14041 agtggtgtat atgaagatac tcagtggtta ataagacttg ttgaaaattt acttagtatg
    14101 accaagatag atgaagggaa attggaagtt aaaaaacatt ctgaactggt tgaggaaatt
    14161 atatcagaag cgttacaaaa aataaaaaaa agaattgaaa atgcacttat agatattaat
    14221 ataccagaac agatattatt tgttcctatg gatgcaaaat taatagaaca agttttaatt
    14281 aatttaatag ataattcttt gaaatattca aaggaagatt gtaagataga gataaatgta
    14341 tatgagaaag atgattatgt ttggtttgaa gtatctgata atggtcctgg tatatcaaag
    14401 gaacttaaaa agcatatctt tgacagattt tttactggag aagaaggagc taaagattcc
    14461 agaaagggtg ttggacttgg attatcaatt tgtaaatcta taattcaagc tcataaaggt
    14521 gaaattatgg tagaaaacaa taaagataag ggttcaactt ttaagtttag tttgcctaag
    14581 gaaaatgaat agttttaaat tttaaaatta gttttggagg aagaaatgag taaaaaactt
    14641 atattgttag tagaggatga taagacaata agaaaattta tatctactgc acttttaaca
    14701 caggattatg atgtcaagga ggctataact ggaaaagaag gtatatctat agctgtctca
    14761 tattctccag atgttgttct tttagattta ggcttagaag atatggatgg aatagaggta
    14821 ataaaagcta tcagacaatt ttcaaatata ccaataattg tagtttcagc tagagagcaa
    14881 gatagagaca aggtagaagt atttgatgca ggggcagatg attacttaac aaaaccattc
    14941 tccatagtag agttattagc aagagtaaga gtagcattta gacattcaca agtagaagct
    15001 caacaaaaag atgatgttaa atctacgttt gaagtagata aattattgat tgattttgat
    15061 aaaagaaaag ttattgttga tgatgttgaa gtccatttga cacctattga atataatatt
    15121 ctttcattac ttgcaaagta tcatggaaaa gtgcttactc ataattttat aataaaagaa
    15181 atatggggta gtgttatagg gaatgagact aagtctttaa gggtctttat ggcaacgtta
    15241 agacgaaaaa tagaaaaaca acctgcaaac ccaagatata taattacaga agttggtgta
    15301 ggatacagat taaatgatga atagttgtaa tatattaatt attagattat gtgcttatta
    15361 atatatatta aaattatata gtttagttaa aataagaatg aagtgtatgt gcttgttgtc
    15421 agtttagcac atgcatttta ttttttagct tttttagtat caataatttt ttagtatcaa
    15481 taatatgaaa tatgttttaa aataagtata tagtgtaatc tgtaataaaa actttggtta
    15541 aataataaat gtatttaaca cttaccttat aataaattta atataaatat taaataataa
    15601 ttattaaaat agtgtaaaat aattacagta aggattataa aaaattttta gaatgtaaat
    15661 tgaaatttag gagtagatgt atgtatatac tgaatttaaa tacaagagag actattgaag
    15721 attttagaga taaattttat gtagcagaaa attcttatct tatattaagt gctccaaaaa
    15781 atttaaaatt gcttaaggaa actttggata tagatgaaat aacttttaat gattgtctta
    15841 aatttgatga aataaccaaa cttgatttat ttgataatta cgatttttta agcctaaata
    15901 catttgaact aagagatgga gaagctgtta tagaagaggt aaatatgtat ttatcagata
    15961 attttatatt ggttgtagtg aatgaagaac actttttatt tgaatttgta aaaaatatta
    16021 ttttgaagaa ctctcaactt gaaaaaaatc cagttattaa tctatttaag ataaactact
    16081 tgattcttag agaagttata aaaaatggtt ttgagtcttt ggaaaaagtt gaagagttaa
    16141 ttcttcaaat agaagatgaa atgatggaca acattaataa gaatcatgta tctagaataa
    16201 gtgatgtaag aggattaaca agaattatag ttaagaatac tagacctctt ttgtatattg
    16261 gggatagaat agttaaggaa aatataagat atttaaaata ttcaaatgta aaaaaatata
    16321 atttagaaaa ttttcaaggt atagattttg gaattgacaa attatacaat ttcgcattgt
    16381 caacacgaga gttagcagat aaattattag atatttattc ttccagagta ggtgagaaaa
    16441 caaataactt aattacaaaa ttaaccttgt taacagccat atcagcacca cttacaatta
    16501 taactggtat atatggaatg aactttagat atatgccaga attaaactgg atttatggat
    16561 atccagcaac tttatttttt atgctatgta taatttttgt tggaattata atatttaaaa
    16621 taaaaaaatt attgtaaatt acagatgatg tttaattgat tttataaaaa tacatcaatt
    16681 gagaagctga tttaagtaaa taaaaaaata ttttaaattg aaaatattta tagaaaatat
    16741 tgacaattat attttctttg ttataattat taaacaagaa gaataataaa ttataaaaat
    16801 ggaggataat actatgaaag gaatattaaa agaactaaca gcaaaacttt atagcttttt
    16861 ttactttatg ttctggggct tttattttag cgctggctat ttcttttaca aaaatatatg
    16921 tacttccttt ctggtgaggc cttattttag tgattttgag cataagtaaa ttttataaaa
    16981 atgattattt tatatattta tataagattt agtgcttgat agattatttt agagaactca
    17041 ttagtgagtt ctctttttta ttttaaatat aaaattataa tattgggagg tagtaaaaat
    17101 gatagtagta ttaaaaatgg gagcagataa aaatgaagtt aaaaaattaa ttgaggctat
    17161 tgggagagaa ggagtagaag ttaatcccat agatggaaca gaattaactg ttttaggttt
    17221 agttggagat actagtaaaa tagatgccaa aagaatagaa gcaaataagg tagttgaaaa
    17281 agttatgcat gtggtagagc cttttaaaaa ggccaataga aaatttcatc cagaaccttc
    17341 aatcataaat gttaatggaa tggaaattgg ttcaaagaaa attgctatga tagctgggcc
    17401 ttgttctgtt gaaacagaag accaaatagt atctatagct aaagatgtga aaaaatcagg
    17461 tgcaggattt ttgagaggtg gagcattcaa accaagaaca tcaccatacg ctttccaagg
    17521 attgaaatat gatggattgg atttattaaa aaaagcaaaa gaaaaaacag ggcttcctat
    17581 agttacagaa ataatgtcaa cacaagatat agatatattt gaagaaaatg tagatgtaat
    17641 tcaagttgga gctagaaaca tgcaaaactt tgatttatta aaagaattag gtaaaacaaa
    17701 taaaacaata cttttaaaaa gaggattatc tgctacaatt gaagagtggc taatgtcagc
    17761 agagtatata atggctggag gaaatgaaaa tgtagttctt tgtgaaagag gtataagaac
    17821 ttttgaaaca tatactagaa atactttgga tttaagtgca attttagctg tgaagaaact
    17881 tagtcattta ccagttatag ttgacccaag tcatgcagca ggtaaatcat ggatggttga
    17941 ctctttatct aaggcagcaa ttgcagttgg agcagatggt ctaataatcg aagttcataa
    18001 tgacccagca catgcacttt gtgatggaaa acaatcgatt aagccaaatg aatatgatga
    18061 attgataagt gaattaaaga ctatcgcatc agcagttggt agagaaatat aatctataaa
    18121 aggatggtta aacgtggaag aaaaactatt agtaaattta aaagaaaata gctacaatat
    18181 atttattaaa aaaaatatac taaagaatat aggagaagaa ataaaaaaaa tatattttgg
    18241 aaataagatt tttattgtaa ctgatgaaaa tatagcaaaa ttatacttgg ataaagtaaa
    18301 aaataattta agtgaatctg gatttgaaat taaatcttta atattaaaat ctggtgaaga
    18361 aacaaaatca tttaatactc ttcctaaaat atacgatagt ttacttgact ttaagttaac
    18421 tagaaaagat ttgattatta ctttaggagg aggggtaata ggtgatttag gtggatttgc
    18481 agcagcaact tttttaagag gtataagttt tattcaaatt ccaacatctt tattagcaca
    18541 agttgatagt tctgtaggtg gaaaagttgg agttgacctt gagagaggca aaaacttagt
    18601 gggaagcttt taccaaccaa aggctgtgtt tatcgaccca aatgtattat tatcacttcc
    18661 agaaaaattc tatagagatg gaatggcaga agttataaaa tatggatgta taaaagacaa
    18721 aacttttttc aataaacttt taagtttaaa aaatagagaa gaagtaatgc aacatataga
    18781 atacattata cataaatgtt gctttattaa aaaaactgta gttgaagctg atgaaaaaga
    18841 ctttggagat agaatgcttc taaactttgg ccatacatta ggtcatgcta ttgagaaata
    18901 ctacaatttt acgggttata cccatggaga agctgttgcc ataggaatgt ataagataac
    18961 tttagaaagt gaaaagatag gaattacaaa aaaagggaca tcagaactta taaaatcaat
    19021 tttaatgaat tataatttgc cttatgagat tgaattaaga gataataaat ctatagtaga
    19081 tgctatatct cttgataaaa aaaatctagg tgatacatta aaaataatac ttttaaaaga
    19141 tattggagag agtattatat ataatactac ttctaaattt tttcaggagg taagataatg
    19201 ggaagtctaa aaatatatcc aagtaaatta tctggagatg taaaaatacc accatcaaaa
    19261 agtatggcac atagggcagt tatttgttca tctctaagca atggaaaaag tagaatttct
    19321 aatatagatt tttctgatga tataatagct actataagag caatgacatc attaggagct
    19381 attatagaaa agaaagaaga tattttagaa atttcgggaa ttttttctaa agaaggtatt
    19441 ttaaatagag agaatcagtt gaatcaacct aaattgacaa tagattgtaa tgaatcaggc
    19501 tctacattga gatttttagt acctatatct ttagcatttg atggtgtaaa aaggtttata
    19561 ggtagaggaa atcttggaaa aagaccactt gatacttatt atgagatatt tgacagacag
    19621 aatataaaat atagttacaa agaaaatcag ttagatttga ttatatcagg taagcttaaa
    19681 ccagatgaat ttagagtaaa aggaaatata agttctcagt ttatcacagg tttactgttt
    19741 atattgccta cgctagagag tgattcaaag ataataatta ctactgagct agaatctaaa
    19801 ggatatttag atttaactct ttcaacgata aaagattttg gggtagaaat tataaacaat
    19861 aactataaag aatttattat aaaaggaaat caaacgtata aagcgagaga ttataaagta
    19921 gaaggagatt attctcaagg agcattttat ttatcagcag atgctatagg agaagatatt
    19981 agcatattag accttaaaga agattctctt caaggggata gtgaagtagt tgaaatttta
    20041 tctaggatgg gaatggaaat attaagagaa ggcaacaaaa taaaaggaat aacaaatggt
    20101 ttaaatggta ctttgataga tgcatctcaa tgcccagata taatacctgt attatctgta
    20161 gtagcatcct taagtatagg gaggactaca ataattaatg ctggtaggct tagaattaaa
    20221 gaatgtgata gacttcatgc aataaatgtt gagttaaata aacttggagc aaatatagag
    20281 gagaaagagg atagtttgat aatcgaagga gtaagcaagt taaatggtgg agtagaggtg
    20341 tggagtcaca aagaccatag aattgctatg acacttgcaa ttgcttcttg tagatgtgat
    20401 aaaccaataa tattaaaaga ttttgagtgt gtatcaaaat cttatccaca tttttttaaa
    20461 gattttaaga tgttaggagg tcgaattgat gagtggaata tggggaaata atttaaaagt
    20521 atcaattttt ggagaatctc atggaaatgc tataggtata aatatagatg gtcttccttc
    20581 ggggattgaa cttgaccttg ataatattga taaagaaatg aagagaagag cacctggaaa
    20641 aaattctata tctacttcaa gaaatgaaag tgatatacca gaaattctaa gtggatattt
    20701 taatggaaga actacaggaa cgccattatg tgcaatcata agaaatagtg atactcgttc
    20761 aaaagattat ggagagctta aaaacttaat gagaccagga catgcagatt tcacaggtaa
    20821 tgtgagatat tctggattta atgactatag aggtggaggt catttttcag gtaggataac
    20881 agctccatta gtattttgtg gggctatatg taaacaaatt ttatcacaaa aaggaataga
    20941 gataggagca cacataaaaa aaattaaaaa tatagaagat atgagttttg attatgtaaa
    21001 tatttcaaaa caacagttat caaatttgca aactttggaa ctacctttac ttgatttatc
    21061 aaaggaagaa gccatgaaaa atacgattat agatgcaaaa aatcaaggag attcagttgg
    21121 tggtataatt gagtgtgcag tagtaggtat taatgtaggg cttggaaatc cattttttga
    21181 ctctgttgaa tctactttat cacatttatt gttttctgtt cctgctgtaa aaggtgtaga
    21241 gtttggttta ggttttgaac ttgcagatat gtatggctct caaagtaatg atgaaatgta
    21301 ttatgaagga aatcaagtta agagcaaaac aaataacaat ggaggaatta taggagggat
    21361 tactactgga atgccaataa ttttcaaagt ggcaattaag ccaactccat caattagcag
    21421 acaacaaaac acagttaata taaaagataa aaaggacgat attttatata ttaaaggcag
    21481 acatgaccct tgtatagttc aaagggctat acctgtaata gaagcagtaa cagccattgg
    21541 aatttttgat ttgatgaaag gacgataata atggaggatt taacgagata tagaaatgag
    21601 attgacaata tagataaaga gcttattcaa ttatttgaaa agagaatgaa tacagttctt
    21661 gaaattgcca gacataaaat gaaaaataac actactatac ttcaaaaaga tagagaagaa
    21721 aaagtactaa gtagagccgt agataattta gataataaag catattcaca agaaacggta
    21781 cagtttttta attctataat ggaaattagt agaggattac aaaaaagatt tatagataat
    21841 gatggtgagc agaaaatcga gtttagttta gattcatcaa ataagaattt tgatttgtca
    21901 aatgtaaata aatataagtc tttaaaagat gaattaaata aaaaaaatat cctagtaggc
    21961 tttcctggaa aatcaggttc atttacagaa gaagcactaa ataaattctt caacaaaaaa
    22021 atatcaaaaa aacaatttaa agaatttgaa gatgttttca tagcacttaa aaataaagaa
    22081 ataaactatg gaataatccc catagaaaat tcatctacag gagctatctc tgaaacttat
    22141 gaccttttga gaaagtacgg tttttatata gttggagaag aatgtataaa aatagaccaa
    22201 aatttaatag ggataaaaga cacaaagctt gaagatataa aagaaatata ttctcatcca
    22261 caaggtatag gacaatgtag tgaattttta aaacaaaata gtacatggaa attgataccc
    22321 tttaataaca cagcaacaag tgcagaactt gtaagaaaac ttcaagataa aacaaaagca
    22381 gcaattgcaa gcaaaaaagc tgcaagtatt tatggattag aaataataag tccttgtata
    22441 aatgatatag caaacaacta tacaagattt gtagtaatca gtaatcaaat acacattgaa
    22501 gaagaatcaa acaaaatgag tgtagtattt tctgttgaac atgaagcagg aaaactttat
    22561 aaagtacttg gatactttgc taaaaataat ataaatatga caaaaataga atcaagacct
    22621 atgaaaaatg cctcatggag atatttcttt tatatagatt ttgagtgttc tatatacaat
    22681 gctaaagtgt acgatttatt agaattgata gaacataata cagcatattt taaatttatg
    22741 ggagtatata aaaataaaac tgaatagata agataaattt ttatttaatt tataattatt
    22801 aggaggtgta agtatgaatt ttttcggtct agtaggtgaa aaactctctc acagtgtttc
    22861 acctcaaatc cacaagagag tattcgagat attgaatatt gaaagtgctt ataaaaactt
    22921 tgaaatttca aaagaagata tatctaagct agacggtgct ataaaattat taggaataca
    22981 aggggtaaat gttactgtac catataagga gcgtattatg aaatatcttg attttatatc
    23041 accagaggca aaacgtatag gagcagttaa tacaatttta ctcagagaaa atatgttata
    23101 tggttacaat acagattact ttggtcttga tagtatgttt aaaatggcta atattgatgt
    23161 tcaaggaaaa gtagcagtta tattaggaac tggaggtgct tctaaagctg ctcttacata
    23221 ttttattgat tctggtatag aaaagcttta tgtttcaact agaaaaaagg atgataaaaa
    23281 attattaaat agtaaagcta tattaataga ttatgaagaa cttaaacata taaaaggaga
    23341 tataatatta aatgctacac cagtaggtat gtaccctaat gtaggaattt caccagtgtc
    23401 aaaatctatt atacaaaatt ttgatatatt aatagattta atttacaatc ctggagaaac
    23461 agagttttta agaattggta atagtatggg taaaaaaact tgtgatggat tatatatgct
    23521 ggtggggcaa gcaataaaat ctcaggaaat ttggcaagat actaaaatag ataatagtat
    23581 tttagatgtt atatataatg aactaaaatt agaatttttg taagggagat tgttatgata
    23641 aataaaacaa aagaaaaatt gatattaata ggtatgccag gtagtggaaa aactacaatt
    23701 ggtaaacttt tggccaaaga atataattgt agtttctgtg atatggatga ttatataatt
    23761 caaatatctc aaaaaagtat agcagagttg ttttcagaag gagaagatat ctttaggaac
    23821 tatgagactc aagcatgtag agaactttct ataagtgata aaacagtgat atctacaggt
    23881 ggaggtgtaa taaaaaagga tattaatatg gaaatactaa aagaaacagg tataataatt
    23941 tttattgata gacctataca aaagattttg gaagatataa atattaattc aagaccatta
    24001 ttaaaaaacg gaaaagatag attgtataat ctttacaatg agagaataaa tctttataaa
    24061 aaattttcag atatagagat tttaaatgat aaatcattaa ataatgctgt atataatatt
    24121 acaaatgcag tcagtgaaaa ttttaaattt gactttaaag aaaaataatc tagggggaaa
    24181 taaaaataat gaatattgtt attgtaggac taggagttat aggaggctct tttgctaaag
    24241 cattaaaaaa agctggatat gaaaatgtat ttggagtaga tgtagattta gaaactttaa
    24301 aaaaagcaga aaaagcaaaa atcataaaaa aaggatgtac tacaggtaaa gagttattta
    24361 aaaaagctga tttaattata ttatctatat atcctagatt agttgtagat tttctaaata
    24421 ataataaaaa cttttttaaa aaagggacta taattactga tactacagga ataaaagaaa
    24481 cacttatcaa tgatgtgttg caaattattc cagatgatat agattttata tttggacatc
    24541 caatggcagg tagggaaaaa aagggtattg attttgcaag tgaacaagtt tttaatggcg
    24601 caaattatat aattactcca actggcagaa acaacataaa aaatttagag ttagttgaaa
    24661 atttaatttt agagattgga tttaaaagag taaaaaagtt aacttcacaa aaacatgatg
    24721 agattatagc ttttacttct cagttacctc atgttatggc agttgctctt ataaatagtg
    24781 atgaagaagg tagagatacg ggtaaattta ttggagatag ttatagagat ttaactagaa
    24841 ttgcaaatat gaatgaagac ttatggagtg aacttttttt aggaaataga gataatttac
    24901 taaaagttat agaaaacttt gaatcagaag taaatttagt aaaagaagct atatttaaca
    24961 atgataaaaa taaattaata gagtatttta aaaaatcatc aataagaaga gaagctttag
    25021 aaaaataaat attaatattt aagctatata tagatgggta taaatataag cgatagtgta
    25081 tttaattgta ttaataaata tggattcaat ataattaaat atgctattga tatatttgta
    25141 cccttaacta ttgttatctt ttagatgata atgatattta tttaaatact ctttattaac
    25201 aatttataaa acttaattgt aaaaaatact tattaatagt aaaataaagt gaatcaatta
    25261 tattataatt gctaaagaga gtgaggtgta gctatttgaa aaaaaataga ttaatagcaa
    25321 agaatatatc aatagcattt atagtactat tcttttttag tgtatttaca ttcttttatg
    25381 taggtaatat taatagagtg ttagaatatg aaacaaatga cataataaca gttacaattg
    25441 ctggatggat tatactttca tttttatttt taggtattat aatttacata ttatattcaa
    25501 aagcaaatag tcaaaaaact atagaaaaag tagcatatac ggattttgta acaggttatt
    25561 ccaactggag aaagtttgaa ttagatgtta caaatttatt aaagaaaaca tcacaaaata
    25621 ataaatatgc aatggtcata ttcgatattg ataaatttaa agcaattaat gatatatatg
    25681 gccataaaaa gggaaattta atattaaaag atattgcaga tactttaaat gaattgactg
    25741 atatcaatga aacttttgct cgtgtaagtg ctgataattt caatatatta ttaacatata
    25801 acaaaaaaga ggatataata aatattatca aaaagattat ggcaaataat gaacttgtaa
    25861 acttatcttt tggaatttat gaaatcaaag ataaggattt atctgtaagt gtatatagtg
    25921 atagagcttc acttgcaaaa tcatcaataa aaaataatag tgatgtaaat tttgcatttt
    25981 ttaatgacaa attaagagag aaattattat ttgaagataa gatagaaaaa gaaatggaat
    26041 atgctcttga aagtgggcaa ttcgtaatgt atttacaacc aaaatacaat attaaattag
    26101 ataaattttg tggaagtgaa gccctagtca gatggcaata tacagaaaaa gaggtcatat
    26161 atccaggtga ttttattcct atatttgaaa aaaatggatt tattagaaag attgatatgt
    26221 acatattaga acaagcttgt aaagaaatcc ggtctttatt tgataaagga atttcacctt
    26281 tacctatatc tgtaaacttc tcaagagttg atttttttaa aaaagatttt attgaaaaca
    26341 tagtaaatat atgtgataga tataaaatac catatagttt aatagaaatt gaaattactg
    26401 aatctagtat gtttggagat actgatactc tatttaatgt tagtagaaac ctacaggata
    26461 ttggctttat agttgcaatg gatgattttg gctctggata ttcttctgta aatatgctta
    26521 aaaatatacc attaaatgta ataaaattag atagaggatt ttttgtttat gataaagatg
    26581 ttgataagag tcaaattgtt ataaaaagca tagtttctct cattaagcaa ttaggaataa
    26641 gggttgttgc tgaaggaatt gaaacaagaa gtcaaataga aatgttaaaa aaagcaaatt
    26701 gtgatattgt tcaaggatat tatttttcaa aaccattacc aattaaagaa tttgaaaaat
    26761 tagtctataa aatatagtca gcgagtctta aatgggaggt ggtgattaag tgataagagc
    26821 aaaatcgtta aaaaatgtac tgagtattgt tttaatattt ttatttacaa taatttcttt
    26881 ttctgatttt gcatttaaaa ctaatgtcca ggaagaagaa aatagtaaaa ttaatttaag
    26941 agaaatatcc ctacaaagtt ccaatgctat aaaaataaaa ttagatagtt ctctatcctt
    27001 tattaaaagt gtggcaaata tggtttctta ttttaatact atagataact caaaaatagt
    27061 tccattatta gctaatatat caaaagaatc tgactttcaa agaatctcta ttgtatctcc
    27121 tgatggaata agtcatacca gtgatggcaa aattatcaat gtgtcaaagt atcagtattt
    27181 taagaaagct attaaaggag aaagtaatat atctgaagtt gtgaaatctc caattgatgg
    27241 aaaagatact tttgttatag ctactcctgt atttaataag aataacaaaa taattggtgt
    27301 tttatacggt tcttactaca atgataaatt agctgaattt atagatataa caagttttaa
    27361 tagtgaaggg tacatagata tatttgaatc tagtggtcaa tttgttttaa aatcttcaca
    27421 tacaaacaaa ctgattaagt caagtagtaa catatatgat atatttaaaa aagcttcttt
    27481 tgatgatggt tatagctata aaaaaatata tgaagataca aaaaataaca agagtggctt
    27541 tacctcatat gaatacaaag gagaaaatcg ttatgctact tatacaccca ttggtgtaaa
    27601 tgactggtat gtaatttctg tgataccaca atatactgta agaagaaaca ttgataaaat
    27661 aaatcaatta gcattttctc ttattttcaa ggtattctta ttgtttatta tgcttataac
    27721 atatattatt tataaaaaca ataaatctca gaaagatata ctaaaagcta acaaagaaat
    27781 ctcatctatt acaaatagca ttcctggagg agtacaaaag tgtaccctgg gtgaaacatg
    27841 caatattaat tttttaagtg atggatttat agagttgttt ggttatacaa gagaagaaat
    27901 aaaaacattg tttaataatg atttttatag tttaatacat aaagatgatg ttgaaagaat
    27961 aaaaaaagaa atttttaaac aactttacaa aaataaaact gttgaattag aatataggat
    28021 tataacaaaa aatggtaata cagtatgggt tttagataaa ggggagctta taacagaacc
    28081 tgatggaaaa gaatattttt gttgtgtaac tgtagatatt actagaacaa aacaattaga
    28141 acaagagatg gaacaaaaaa atctagaact tgaaatgata tcagaaaatg ttttaggtgg
    28201 tataattata acagaattta atgatgattt tactataaaa tacgctaact ctggttatct
    28261 ttcaatgatt ggatatacac gtgaacaatt agaaaatgaa cttaaataca aagcttgtaa
    28321 tcttgttttt tatgaagata gaaagaaggc tcttgaaagt atacaacatc aattaaacac
    28381 aaaaggaata gctgtatatc aacatagaat aagaagaaga gatggtaata ttatttgggt
    28441 ttctataaaa ggaaggctta ttgttgatga tgatggtatt gaaaaaggta tttggattct
    28501 aaatgatata acagatttaa aaaatgcaga acaaaaactt aaaataaatg aagaaagatt
    28561 tagaattgca ttaaagcaaa catcaaacac tatatttgag tatgatataa aaacaaagtc
    28621 acttttaaat actagtaaag agcttgataa atataatatt tataaaatta ctaaaaatgt
    28681 tccatattct ctagtagaat taggagttat tcataaagat tttagtgatg attttataaa
    28741 tatgtatgaa aatgtaataa atggagcaaa aaaagcaagt tgtgtagtta agatgaaact
    28801 tccagatgaa aattatatat ggaataaagt taccttgact acgatttttg atgaagatgg
    28861 taatcctgta agagcaattg gtatacagga agatataagc aaacaaaagg aagcagagat
    28921 aagatacaat caagaaggta agtatcattc agctatattg tcggaagcaa tgataactta
    28981 tgaaataaat gtatcaaagg atacttttat caaaggaaat gaaagttggc aaaaaccatt
    29041 tggaattaag cctgacaata actattctca aatggtaaaa actatagcaa atagtattgt
    29101 acataaagac aataaagaaa catttttaaa tacattttta tgtgaaaact tattggatgc
    29161 atataaaaat aatgtgactg aaataaaatt agaatatcga agaatgaatc aagaaaataa
    29221 aatgatttgg gtcatttgta caatgcactt aataaaagat tctattacga acgatataaa
    29281 agcacttgct tatgttaaag atattgacaa gcaaaaaaat gaagaaatta gattaaaatt
    29341 aaaagctgaa agagatactc ttacaggatt atataataaa ggtactacag aaaaattgat
    29401 taatgatttc ttgaactctg aggaagcaag cttaggaatg catgcatttt taattgttga
    29461 tatagataat tttaaatctg tgaatgataa tttaggacat gtatttggag ataaagtatt
    29521 atttgaagtt tctaaaaacc taaaacctat atttagaaaa gatgatatag taggtagaat
    29581 tggtggagat gaatttatag tattcttaaa aaatattcag tcttttgaga atatcaaaaa
    29641 gaaagcagaa aaaatatgcg atatatttag aaattcttat acagaaaata aaaagacata
    29701 taaaatatct ggaacagttg gaatttcatt tgtaccagaa catggaactg tatttgaaga
    29761 actttataaa aaagcagaca tagcacttta ttatgcaaag agcaaaggaa aagataagta
    29821 tgcactttat aatgattgta tctaccaaaa tgaacttgaa aataatataa gtgataataa
    29881 tataaagtta gcagataaat gtgagaaatc caaaccagta cttaaagaaa ttcttgattc
    29941 tattgataat tatatctata tagtgaatcc aaatacttat gaacttcttt ttgtcaataa
    30001 taaggtgtct cgtttggatt tagagataaa attaggagaa acctgttata aatcactatt
    30061 aaaatctgat agaccatgta ataattgccc tcttaacgga ttagaagaaa ataagcattc
    30121 aaaattcaaa atagagacaa atacatttgg taaaaatatc agtatagcaa gttggattaa
    30181 ttgcatagat ggagaataca actgtcttat agagtgtata gattcttctt tatacaaaaa
    30241 taaataaaaa aggactatga agatatgtta aatagtataa ctttgatact tggtataata
    30301 tttacaattt actattttta tctcaaaata gtttttggag gaatttcatt tagtgagatt
    30361 ttcttagttg taggaattgt actaattatc tatcaaatat ttaagaaaaa aattaaagaa
    30421 aagaaggttt tttatagggt gttaaaaata ataatcagca tttttttaat agtatttgta
    30481 gttactgaga gtctaattat tttttatccc aaaaatagtt tagaatcaaa aagtgattat
    30541 ctcttaattt taggagcttc tgtaaaaaag actacaccaa gtacaaccct gaagggtagg
    30601 ttagacactg cattgaaata cctaaaaatt aatgataatt gttatgtggt agtatctggt
    30661 ggtaaaggaa gtggagaaaa aataactgag gcaaaagcta tgaaagatta tcttataaaa
    30721 aatggtatag ataaaaatag gataatagaa gaggataaat ccacgaatac ttatgagaat
    30781 tttaaatatt caaaattgaa gatagaagaa catagtcaaa gaaaactaag cgatttaaaa
    30841 gtaaaaatag taacaacaga ttttcatgtt ctcagaagta aaatattagc atatagaaat
    30901 ggatataaaa atacgtcttt ttatgctagt aaatcaaaac tttcatttgt accaacttac
    30961 tatacaagag aattttttgc attatggaaa acaatcattt ttgatagata ataaataaaa
    31021 agactagata taaactcata tctagtcttt tctattccct taattctaat ccattttcca
    31081 actttacttg ttgtagaaat ttcaatattg ggatttacaa gtaattgctt ataagaagtt
    31141 ttatattttt cgattccaaa atataa
//
LOCUS       DAEPHU010000050        30734 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 01A10CD0081
            SAMN05941466-rid12468953.denovo.050, whole genome shotgun sequence.
ACCESSION   DAEPHU010000050 DAEPHU010000000
VERSION     DAEPHU010000050.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941466
            Sequence Read Archive: SRR6291087
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 30734)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 30734)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068158.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 22:43:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,892
            CDSs (total)                      :: 3,805
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 87
            rRNAs                             :: 8, 1, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 55
            CDSs (without protein)            :: 55
            Pseudo Genes (ambiguous residues) :: 0 of 55
            Pseudo Genes (frameshifted)       :: 21 of 55
            Pseudo Genes (incomplete)         :: 28 of 55
            Pseudo Genes (internal stop)      :: 16 of 55
            Pseudo Genes (multiple problems)  :: 8 of 55
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..30734
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941466-rid12468953.denovo.050"
                     /strain="01A10CD0081"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            complement(<1..884)
                     /locus_tag="KR231_002357"
     CDS             complement(<1..884)
                     /locus_tag="KR231_002357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009243519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional lysozyme/C40 family peptidase"
                     /protein_id="HBH0004724.1"
                     /translation="MKLKHIAIIGSLFPILFSLVLFFGVLISADSDDENSNFSSGITG
                     MNLSAEVLKHQTMVEKYARENGISEYVNVLLAIIQVESGGTAEDVMQSSESLGLPPSS
                     LDTESSIKQGCKYFASLLSSCKNQDIDDLNVAIQSYNYGGGYVGYVAGNGKKHTFNLA
                     ESFAREKSGGKKVTYTNPIAVAKNGGWRYGYGNMFYVELVNQYLTVPQVSGELAQKVM
                     NEALKYQGWKYVFGGSSPTTSFDCSGLTQWCYGKAGISLPRTAQAQYDATQHLPLSQA
                     KAGDLVFFHSTYNAGSYVT"
     gene            complement(881..3085)
                     /locus_tag="KR231_002358"
     CDS             complement(881..3085)
                     /locus_tag="KR231_002358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBH0004725.1"
                     /translation="MKERIQSAFTKRKILHFLKMALFVVALSLILLSLLGTVAHATGL
                     VDDTINAENLYSKYPLSNYQLDFFVDNSWSWLPWNWLDGIGKSVQYGLYCITNFVWTI
                     SLYLSNATGYVVQEAYKLDFINDMADSIGKSIQTLAGVTENGFSSTGFYVGFLLLIIL
                     VVGMYVAYTGLIKRETSKALHAVINFVVVFVLSASFIAYAPDYIKKINEFSSDISTAS
                     LDLGTKIMLPNSDSEGKDSVDLIRDSLFSIQVQQPWLLLQFGNSNAEEIGTDRVEALV
                     SASPEDEDGKTREEVVKTEIEDNDNNNLTIPQVVNRLGMVFFLLFFNLGITIFVFLLT
                     GMMLFSQILFIIFAMFLPISFLLSMIPSYESMAKQAIVRVFNTIMTRAGITLIVTVAF
                     SISSMFYNISTDYPFFMVAFLQIVCFAGIYMKLGDLMSMFSLNAGDSQSMGRRIFRRP
                     YLFMRHRARRMEHRIARAVSAGGISGGVAGAVAGSAVAGKRAERKNTASKENRGNTTS
                     SMGQRAGSKVGAVLDTKNKVKDKANAVKENIKDMPTQTAYAVYSAKEKAKSSVSDFKR
                     GMVQEQQSRQTGRLEKQEQHKKSIAVKRMELQKAQEARQAQRKADGSATTGATRPHER
                     PATASTVSKTGAEKMQEVKRPATTPTTKASEPVKTSGVKERPLSSSTPDGKATQSTYR
                     QNVEKVTVSKETRQNYTKDRRTKVQQTQTVQKNQQTTEKIRNLVTKKGQKKK"
     gene            complement(3085..5535)
                     /locus_tag="KR231_002359"
     CDS             complement(3085..5535)
                     /locus_tag="KR231_002359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HBH0004726.1"
                     /translation="MFPIKYIDNNLVWNKDNEVFAYYEMIPYNYSFLSAEQKFIVHDS
                     FRQLIAQSREGKIHALQIATESSIRSMQEQSKKLVTGKLREVAVQKIDEQTEALVSMI
                     GDNQVDYRFFLGFKLMVTEEQLNLKNIKKSAWLTFKEFLHEVNHTLMNDFVSMPNDEI
                     NRYMKMEKLLENKISRRFKVRRLEIHDFGYLMEHLYGRDGIAYEDYEYQLPKKKLKKE
                     TLIKYYDLIRPTRCVIEESQRYLRLEHEDKESYVSYFTVNVIVGELDFPSSEIFYFQQ
                     QQFTFPVDTSMNVEIVENRKALTTVRNKKKELKDLDNHAYQAGSETSSNVVDALDSVD
                     ELETDLDQSKESMYKLSYVIRVSAPDLDELKRRCDEVKDFYDDLNVKLVRPAGDMLGL
                     HSEFLPASKRYINDYVQYVKSDFLAGLGFGATQQLGENTGIYMGYSVDTGRNVYLQPS
                     LASQGVKGTVTNALASAFVGSLGGGKSFCNNLLVYYAVLFGGQALLLDPKSERGNWKE
                     TLPEIAHEINIVNLTSDKDNAGLLDPFVIMKNVKDAESLAIDILTFLTGISSRDGEKF
                     PVLRKAVRSVTQSENRGLLHVIEELRKEDTAISRNIADHIDSFTDYDFAHLLFSDGTV
                     ENAISLDNQLNIIQVADLVLPDKDTTFEEYTTIELLSVSMLIVISTFALDFIHSDRSI
                     FKIVDLDEAWAFLNVAQGETLSNKLVRAGRAMQAGVYFVTQSAYDVSKESLKNNIGLK
                     FAFRSTDINEIKQTLEFFGIDKDDENNQKRLRDLENGQCLLQDLYGRVGVVQIHPVFE
                     ELLHAFDTRPPVQRNEVE"
     gene            complement(5513..5911)
                     /locus_tag="KR231_002360"
     CDS             complement(5513..5911)
                     /locus_tag="KR231_002360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009274602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HBH0004727.1"
                     /translation="MKKIKSYTGIWNVEKVLYAINDFNLPFPVTFTQITWFVITEFII
                     ILFGDMPPLSMIEGAFLKYFGIPVALTWFMSQKTFDGKKPYSFLKSQITYALRPKITY
                     AGKAVKLHKQILNETITAVRSVNYVPDKIY"
     gene            complement(6029..6532)
                     /locus_tag="KR231_002361"
     CDS             complement(6029..6532)
                     /locus_tag="KR231_002361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004843360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antirestriction protein ArdA"
                     /protein_id="HBH0004728.1"
                     /translation="MIDDMAVYIANLGRYNEGYLVGAWFTFPIDEEDVKEKIGLNEQY
                     EEYAVHDTDNFPIDIGEYVSIEELNEMYEMIEELPDYIVECLDEFISHYGTLEEVVEH
                     KDDIYFYPDCETMTDVAYYYIDELNALGDIPANLQNYIDYEAYGRDLDMGGRFIETSR
                     GICEIPY"
     gene            complement(6550..7053)
                     /locus_tag="KR231_002362"
     CDS             complement(6550..7053)
                     /locus_tag="KR231_002362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004843359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antirestriction protein ArdA"
                     /protein_id="HBH0004729.1"
                     /translation="MQETRVLVETGRTNGEETTSYWFDLPIDVAEFEEKLGVGAESQD
                     YRIIEKVLPYADEVHEHTSVYQLNELDFMYRQLSADMQEEYVELLTVFENLEALYICR
                     NVITVYHDCKSMIDVARQKLMNDPTFKHLSEDCQAYYFDFEAYASHLLENKRYLVTEN
                     SIFELPE"
     gene            complement(6972..7268)
                     /locus_tag="KR231_002363"
     CDS             complement(6972..7268)
                     /locus_tag="KR231_002363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005339688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HBH0004730.1"
                     /translation="MNDIFKDMQAKVGCEYISDLPSYKRKVWHEMKRLNPADYEEKQL
                     KDFSKYVFGMSYQTLKDVMKQQKGREEQCRKQGYWWKREEQMAKKQHHTGLTYR"
     gene            complement(7367..8140)
                     /locus_tag="KR231_002364"
     CDS             complement(7367..8140)
                     /locus_tag="KR231_002364"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0004731.1"
                     /translation="MKGIKVLMISDEMRVDILHAVFINKNFIKDEENCNYEKYLLELV
                     NKSIYFREKSNFAEYVPPKSENHGECDCNSPNYQMDFKLLESTTRLHASKELTGQIQK
                     FCDGVIGKCPPRRPNTQMTVTRLFASLRDYDCESLHSCLTEKYEYGTIEFDIQTYVKL
                     LTFKKNLFFFFPYKFSFNTCYNFKYALDSIRIALEKDFRESNLFREKYYAEYDTFLAY
                     IYEDNLIISKFEQDGKLQMIDCIYLFKSQTYSKLYEYTW"
     gene            complement(8200..8421)
                     /locus_tag="KR231_002365"
     CDS             complement(8200..8421)
                     /locus_tag="KR231_002365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002570387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0004732.1"
                     /translation="MNFGQNLYQWFLSNAQSLVLMAIVVIGIYLGFKREFSKLIGFLV
                     VALIAVGLVFNAGGVKDVLLELFNKIIGA"
     gene            complement(8422..8556)
                     /locus_tag="KR231_002366"
     CDS             complement(8422..8556)
                     /locus_tag="KR231_002366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017143882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3789 domain-containing protein"
                     /protein_id="HBH0004733.1"
                     /translation="MWELVKDFLLVSMGMGIGVVLMCILSISKEADYEMKQLEESEDN
                     "
     gene            complement(8569..9765)
                     /locus_tag="KR231_002367"
     CDS             complement(8569..9765)
                     /locus_tag="KR231_002367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003062030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
                     /protein_id="HBH0004734.1"
                     /translation="MVLNEEQWIKELREKRIAYGISQGRLAVASGITREYLNKIESGK
                     MKPSKELLETLHKELARFNPEAPLTMLFDYVKIRFPTLDIQHIIKDILKLNINYMLHE
                     DYGHYSYTEHYSLGDIFIYTSADEEKGVLLELKGRGCRQFESYLLAQQRSWYDFLMDA
                     LIDGGIMKRIDLAINDHTGILDIPELAEKCRKREYIGKSRSYKYYQSGELIKHREDDR
                     EYMGSTLYLGSLKSDVYFCIYEKDYEQYVKLGTPLEEADIINRFEIRLRNERAYYAVR
                     DLLTYYDAEQTAFSIINQYVRFIDEEPDKRKNDWKLNDRWAWFIGDNRQSLKLTTKPE
                     PYTLDRTLRWVQRQVAPTLKMLKKIDKGNGTDYMETIEKQAILSEKHEMIIKQQTTPA
                     KDLVES"
     gene            complement(9950..11344)
                     /locus_tag="KR231_002368"
     CDS             complement(9950..11344)
                     /locus_tag="KR231_002368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008787614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HBH0004735.1"
                     /translation="MRMILNKGHRIRASDKNLVYRFSMGTLLFVFVAVILLLNTKQLM
                     RTDWEHFSLLDNGFTLSLYNFITILIATGVCALVAFLYYRFCYDSFKKLLHRQKLARM
                     ILENKWYEADTVQDSVFFTDLQSRSREKIVWFPKIYYQMEKGLLHIRCEITLGKYQDQ
                     LLRLEDKLESGLYCELTDKTLHDGYIEYTLLYDMIANRITIDEVRAENGCLRLMKNLV
                     WEYDALPHALIAGGTGGGKTYFLLTLIEALLHTNAVLYILDPKNADLADLGTVMGNVY
                     HTKEEMIDCVNAFYEGMVQRSEQMKRHPNYKTGENYAYLGLPPCFLIFDEYVAFFEML
                     GTKESVGLLSQLKKIVMLGRQAGYFLIVACQRPDAKYFSDGIRDNFNLRVGLGRISEL
                     GYGMLFGSDVKKQFFQKRIKGRGYCDVGTSVISEFYTPLVPKGHDFLQTIGFLAQARQ
                     DGTATCEAKGDGSD"
     gene            complement(11438..11875)
                     /locus_tag="KR231_002369"
     CDS             complement(11438..11875)
                     /locus_tag="KR231_002369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004056026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0004736.1"
                     /translation="MCEECYSDENRITPLLNPLDCLENHTQYICGTCGRCICIEHDPN
                     RGLQRWNFPFKSLEIAKLYLRTADYTTKSSCGIYEIENSKGRVSYKIFAGNEDLHLFL
                     KKNKDKKCKQMTPVFNVGEYKEYPHTEVRKLTSDEIKQYMSER"
     gene            complement(11977..12360)
                     /locus_tag="KR231_002370"
     CDS             complement(11977..12360)
                     /locus_tag="KR231_002370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009588269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HBH0004737.1"
                     /translation="MRLSNGFVIDKEKTFGELKFTAVRDVFLQNEDGTPSTQLKKRIY
                     DLKCSLHGGIIPVSVPPEVPLREFPYNAVVELVNPVADTVSRKTYTGADVDWYVKAED
                     IVLKNKGNQNTGTSQNHTPQGQPKK"
     gene            complement(12376..12702)
                     /locus_tag="KR231_002371"
     CDS             complement(12376..12702)
                     /locus_tag="KR231_002371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HBH0004738.1"
                     /translation="MEMKYVVPDMAQSFGTLEFAGESEPIFERDKNNRKVIARRSYNL
                     YSDVQKGENVVVEIPVQAGEKHFKYEQKVKLVNPKLYGRGYAIGDVGHTDYVLVADDI
                     VAVEEK"
     gene            complement(12828..15872)
                     /locus_tag="KR231_002372"
     CDS             complement(12828..15872)
                     /locus_tag="KR231_002372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SrtB-anchored collagen-binding adhesin"
                     /protein_id="HBH0004739.1"
                     /translation="MKKILKRLCTGVLAFATVVTALPSTAVHAESKQYWTESEERVGI
                     VEKVMNDGSIGSTFNEGHLTVEGEDAYCIDINTDFKNGYKTRADASTRMSADQISDVA
                     LSLEYVKQYGEAHKELNYKQVYLLEQCVVWQRLSVHLGWQCDNVRASYDEIPKATQDE
                     VFAGAKAFVKENKGRYECGGYIYSGEGQELGQFWAKLNVGNAKLQKTSSNTSITDGNG
                     NYSIAGATYGVFSDKDCTKQLATLTTDKNGNTDVVEVKAGTVYIRELSAPAGYKVDTT
                     VYSLKVEAGKTATLNVSDTPKVTDTLIELFKIDMETQKDNPQGNASLEGAEFTWKYYA
                     GFYNKDNLPAEATRTWVTKTIAETDSDGTTHYITKLADAYKVSGDSFYMQDGKAILPL
                     GTLSVEETKAPNGYLLDGAYMQAGDKSEQIKGLYLTQITEDGDLAVLTGSNQFSVSDK
                     VIRGGVKIQKRDLETSDTKPQGSATLKDTAFDVISLNDNSVLVEGKLYKKNEVVKTIR
                     TDIEGVASTSADLLPYGKFRIVESEAPDGYLTDGAKPIDFAITENGKIVDLTDEAHSI
                     YNQIKRGDIEGVKIGAGTHKRLADVPFRITSKTTGESHVVVTDDNGQFSTSAEWTSHK
                     HNTNAGKTSEDGVWFGTSEADDSKGALPYDTYIIEEMRCDSNKGFELIPPFEIVVSRN
                     NLVIDLGTLTDEYEKEISIHTTATSKDSEKTILAGKEVTIVDTVKLDGLTKGTKYQLK
                     GWQMLKEENAELIIDGKRVENDYTFIADDEEMKVEISYTFNASELGGKNLVTFEELYD
                     LSNPDEPVKVAEHKDIEDDGQTVLITERIIKIHTTATDKDGNKEIEAGKDVTIIDTVT
                     LEGLEVGTQYKLVGWQMLKEENAELLINGKRVESDYTFTADSETMKAEVAFTFDATSL
                     DGKQLVTFEELYDLSNPDEPKKVTEHKDIEDEGQTITFNEKPEVPEKLETPQTPEKPN
                     RPSDSPKTGDSTNVMAFLVMLLTSAGGLAGTYLYKRRTMKKS"
     gene            complement(16115..17479)
                     /gene="rlmD"
                     /locus_tag="KR231_002373"
     CDS             complement(16115..17479)
                     /gene="rlmD"
                     /locus_tag="KR231_002373"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HBH0004740.1"
                     /translation="MLSKNEMYIVDIVDIGQGGVGVGKYNGITVFVEGGLIHDKVKVR
                     INKVKKNYAVGDIVEIIEKSPFRVKRVCSDNLRDCGGCQIQDLDYNKQLEMKTNEVKQ
                     VLSRIGKLEDVEVHDTIGMDNPYRYRNKAQFPIQKNNGIPIIGFYKKKTHDVISTEKC
                     VIQHEINDKIVKIIKTYIRAYKVSIYDEKTHTGLIRHLVTKIGFTTKEVMVVLVANGN
                     KLPYLKELASVLKENIPGFKTLVVNVNQKDTNAILGRENIVIYGDGKINDYIGDLVFE
                     ISPLSFFQVNPVQTKVLYDKALEYANLNDTDTVFDIYCGIGTISLFLAQKAKKVYGIE
                     IIDDAIKDAKINAKLNNIHNAEFYVGKAEEIVPKMYREGKTANVVVVDPPRKGCDEKV
                     LETIVSMNPERIVYVSCNPSTLARDLDYLNVHGFKCVEAQPVDMFPHSTHIETCVLLQ
                     RRTM"
     gene            complement(17654..19414)
                     /gene="pyk"
                     /locus_tag="KR231_002374"
     CDS             complement(17654..19414)
                     /gene="pyk"
                     /locus_tag="KR231_002374"
                     /EC_number="2.7.1.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate kinase"
                     /protein_id="HBH0004741.1"
                     /translation="MLNNVKKTKIVCTLGPASQSEEVLTQLMQNGLNVCRFNFSHGSH
                     EEHKERIDMAKKVREKLNKPVAILLDTKGPEIRTGNFEDPEVFLEEGQKFTITMKDIM
                     GTKEMCTVSYKGLAEDVKSGDSILIDDGLVGLRVKEINGEDIVCVVENSGIVKNHKGV
                     NVPGVKINLPAITPKDISDIEFGISQGIDYIAASFVRKASDVLAIREVLENNNATDIQ
                     IISKIENQEGVENLDEILKVSDGIMVARGDLGVEIPTEEMPIVQKMMIKKCNELAKPV
                     VTATQMLDSMIRNPRPTRAEVTDVANAIYDGTDAIMLSGETAAGKYPVEAVKMMATIA
                     KRTEETLDYDRLLKENGTNNVTVTDAISHATCTTAVDLNASAIITSTSSGYTARMVSK
                     FRPKSPIIATTNNEKTMNKLALTWGVYPVKSSVAGNTDEVIEKAIEAARQADYIDNGE
                     LVVITAGVPVGVSGTTNLIKVHVISEEIVQGIGVGTQTVEGKVRIIKNGNACVDFNEG
                     DILVSTATDAEMNNYIEKAGAVVTENGGMTSHTAIVGINLDIPVIVSAADITNLVKDG
                     EVVTVDASRGVVYRGSTRVL"
     gene            complement(19466..20425)
                     /gene="pfkA"
                     /locus_tag="KR231_002375"
     CDS             complement(19466..20425)
                     /gene="pfkA"
                     /locus_tag="KR231_002375"
                     /EC_number="2.7.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phosphofructokinase"
                     /protein_id="HBH0004742.1"
                     /translation="MKTIGLLTSGGDAPGMNAAIRAVVRSAIYYGCKVYGINRGYKGL
                     LEEDLTEMNLSSVGDIIHRGGTILKSSRCEEFKTEEGRLKAVKILKKYKIDCLVVIGG
                     DGSFAGAQKLSDLGFPAIGIPGTIDNDLAYTDYTIGFDTAMNTIIDAIGKIRDTSSSH
                     ERVNIVEVMGRHCGDLALYAGLAGGAETIIVPEVEITVDEVALRLKTTQKRGKRHSII
                     VLAEGVGSASDLEKELKKESGADLRVTVLGHVQRGGSPTVSDRILASRLGVRAVELLL
                     DGKSARVVGIKENKIIDLEISEALAQKKVFDKEAYEMAKILSI"
     gene            complement(20634..24203)
                     /locus_tag="KR231_002376"
     CDS             complement(20634..24203)
                     /locus_tag="KR231_002376"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit alpha"
                     /protein_id="HBH0004743.1"
                     /translation="MNKDFAHLHVHTEYSLLDGFSRVKKLIKRAKELNMSSIAITDHG
                     CMFGVIDFYKTAIKEGIKPIIGCEVYTAARGLRDKDPNYDKYQGHLVLLAKNMEGYKN
                     LIKIVSTSYVEGFYYKPRVDMEELKKHNKGIIALSACLAGDVARALMNRNYEKAKQFA
                     LDYRDIFGEENFFLEIQDHNLPEQKEVNSGLVKLSKETGIPLVATNDVHYVNKEDSKI
                     HDVLMCIQMGKTLNDPNRMRFGSDEFYLKSREEMEELFPYALEAIDNTVKIADMCNVE
                     FDFNTIHLPKYDVPEGYTPETYLRELCFNGLKERYDNPSNEILERLNYELDVIEKMGY
                     VEYFLIVWDFINFSKENNIIVGPGRGSAAGSIVAYTLKITDIDPIKYSLLFERFLNPE
                     RISMPDIDIDFCYERREEVIDYVKRKYGDDHVAQIITFGTMGAKAAIRDVGRVLDIGY
                     NKVDKVAKEIPFALGMTIDKALDTNPNLKELYDQDPETKEIINISKQIEGMLRHASTH
                     AAGVVISKNPVDEYVPLYKHQDAITTQFTMTTLEELGLLKMDFLGLRTLTVIRDTLDL
                     IEKNRVIKNYTEKIDFSKMDYDDPKVYEMLSSGNTLGVFQLESAGMRSFMKQLKPDNF
                     EDIVAGISLFRPGPMDSIPAYIKNKSNPKDVTYLHEKLKPIMEVTYGCLVYQEQVMQV
                     VRDLGGYSYGRSDLVRRAMSKKKMDVMEEERQYFIHGKFDEDGNIEIAGCIRNGVEEE
                     IANKIFDDMIDFARYAFNKSHAAAYGVLAYETAYLKTYYPVEFMAALITSVMGNTDKV
                     VEYIRECKALEIDVLPPDINKSFSKFSVEGDNIRFGLAAVKNVGVNIINNIIAERESN
                     GLFVDLVDLVKRLDQKDTNKRVIESLIKCGAFDNISENRASLMAGYESLLESVSMDRK
                     KNVQGQISLFDAFGDSEEDSDFQQIYSLPKRQEYEERERLNLEKEVLGMYVSGHPLSQ
                     FEKELQEKTSMDNGKLNSLKEEEESYLQMNETDVIMGGMIVTKTIKTTKRNEIMAFIE
                     LEDLYGAIEIIVFPQLLQKYNVILNEDNIIYVKGTLSIKEGENAKLIAREIKDINDDT
                     DFADRNYNSGRTRNVENIKPESGKKLYLKIDSMSDTDTTNNIVEIAKQYPGNDSIYLY
                     PMDENINGKRKAYKMTGALTCICDEFINNLEELLPKDNIKVKA"
     gene            complement(24360..25307)
                     /gene="whiA"
                     /locus_tag="KR231_002377"
     CDS             complement(24360..25307)
                     /gene="whiA"
                     /locus_tag="KR231_002377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436252.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein WhiA"
                     /protein_id="HBH0004744.1"
                     /translation="MSFSTETKNELARVISGNECCNIAELSALVKSGGSIQIVGYKKL
                     NLKITTELNSIARKVFKLLKKNFNINTTISVNKNQMLKRNNSYVLMVTSEMGSEMLLK
                     KLGILEDKEGFFTINKISENLIKHEGCKRAFIRGAFLGGGSISDPEKNYHMEFVTNNE
                     EFADSLKELINSLGFNSKIVARKNNHVVYIKESEQISDLLSIIGGHHALLSLQNTKIV
                     KEMRNNVNRIVNCETANLSKTVNAAVRQVENIKLIQETIGISSLPENLQEIAKIRIEY
                     EDMTLKELGEMLEPPIGKSGVNHRLRKIEEIATDLKKKS"
     gene            complement(25324..25749)
                     /locus_tag="KR231_002378"
     CDS             complement(25324..25749)
                     /locus_tag="KR231_002378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416968.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HBH0004745.1"
                     /translation="MREEVSAGGVVLFGNTILLLRKFNGDWVLPKGKVEEGENNQEAA
                     LREVSEETGVKADILKYLGEIHYTFKENWDENRAVHKTVFWYLMQAKNMDTIPQKEEG
                     FIDAKFIHLDRVVDLARYDDEKEIIKVALQEIKKRLKKN"
     gene            complement(25818..26924)
                     /locus_tag="KR231_002379"
     CDS             complement(25818..26924)
                     /locus_tag="KR231_002379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YvcK family protein"
                     /protein_id="HBH0004746.1"
                     /translation="MAKLLIIVGILGWIALIVSLFIYKKAKNEKVKLFQRSIVENREP
                     NVVVIGGGTGQSVFLRGLKHTTQNITAIVTVADDGGGSGVLREDLGMLPPGDIRNCLL
                     ALANIEPTMNEVMQYRFTEGLLKGQSFGNLFLAAMNGLYGNFEKAVYKLSEIFAITGR
                     VLPVTLEDVNLVAKLENGNIINGESSIPEESKIQKSSIDKIFLNPKDVKPLKDVIASI
                     YDADIIIMGPGSLYTSIIPNLLVEGIVDAIKSSVAPKVYIANIMTQPGETEGYNVLEH
                     VNAIVKHTDENLIDYVIANNEILPEEMLDLYKQDGAEQVLLDKKQKDKLKEMGIKTVE
                     KNLIEIKNNYIRHDAKYISNIVIELALNHNYNKS"
     gene            complement(26936..27793)
                     /gene="rapZ"
                     /locus_tag="KR231_002380"
     CDS             complement(26936..27793)
                     /gene="rapZ"
                     /locus_tag="KR231_002380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNase adapter RapZ"
                     /protein_id="HBH0004747.1"
                     /translation="MKFVIVTGLSGSGKSETMRALEDMGFYCVDNLPPALITKFAELC
                     YQPNSSIDKVALGIDIRGRKFFEALHESLNYLEKENYEYEMVYLDCNDDVLLKRYKMT
                     RRNHPLAKDMQIPEGIKMERKIMEPLKELSTCIIDTTNMKPKDLKEEIKKIYSSGEDN
                     PNLTISVVSFGFKHGILADADLVFDVRFLPNPYYVEELRAKTGDDKEVRDYVMNSKIS
                     EEFYVKLLDMIHFLVPQYIEEGKQHLVIGVGCTGGRHRSVTITNLIAEDLSNKGYRVV
                     KKHRDSMLR"
     gene            complement(27824..28537)
                     /locus_tag="KR231_002381"
     CDS             complement(27824..28537)
                     /locus_tag="KR231_002381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PHP domain-containing protein"
                     /protein_id="HBH0004748.1"
                     /translation="MKILADYHTHTLYSHGKGTIEDNVKVAISKGIKTIGISDHSYKH
                     IAYGVKKKDILKMREEVDYLNDKYTDINILLGMECNILDDKGNIDMDDKFIRDFDYIM
                     AGYHFGSTPTSLRSLLNHCNNYIFKTEKAKEYNTKAVINAISNNDIFIITHPGDKGDV
                     YIEEVAKTAKKTNTRLEINSSHSFLNVNQLNKIKGLENKFIIGSDAHCPERVGDFELA
                     MKTISDSNLDISLVENIII"
     gene            complement(28541..29455)
                     /gene="murB"
                     /locus_tag="KR231_002382"
     CDS             complement(28541..29455)
                     /gene="murB"
                     /locus_tag="KR231_002382"
                     /EC_number="1.3.1.98"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate dehydrogenase"
                     /protein_id="HBH0004749.1"
                     /translation="MNNQDIYINLLNILSKEDIKVDEPMKKHISFRVGGPADILVRPR
                     TEEQLKNVLKLVKEESIPYLIIGNGSNILIKDGGIRGVVIELADNFNSYEINDTRMTA
                     QSGALLSVLGKALQKQELKGFEFASGIPGTLGGALAMNAGAYGGEMKDIVKSVRLMDM
                     EGNIFELSNEQMEFGYRKSIISKNGYIALSAELELQEGNYDEIKSLMDDLATRRITKQ
                     PLNFASAGSTFKRPTGYFAGKLIEETGLRGLTLRGAQVSEKHCGFVVNQGEASAKDIL
                     DLIYVIKSAVYAKFGVMLEEEVKILGED"
     gene            complement(29728..30498)
                     /locus_tag="KR231_002383"
     CDS             complement(29728..30498)
                     /locus_tag="KR231_002383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate/nitrite transporter family protein"
                     /protein_id="HBH0004750.1"
                     /translation="MSKGFLTPGETAQATISAGIKKANISTQNAILLGLFGGAFIGFG
                     ALGSMIVSQTFGKIDPGVASFLSAMVFPVGLMLVVVAGAELFTGNTLMAIALMDKKIT
                     LGKMLRNWGLVYFANLVGSILLVALVFYSSTLTGDAATKAIAVAEAKVNSTIASMFLK
                     AILCNILVVLAVWMATASQDIMSKLASCWTVIMLFVLCGFQHSVANMFFIPMGMALGA
                     NITMVQFITNLVFVTLGNIVGGSIVVGGIYYLCYVKNS"
BASE COUNT         8537 a         6661 c         4563 g        10973 t
ORIGIN      
        1 gttacatacg aaccagcgtt ataggtggaa tggaaaaata ccaaatcgcc agcctttgcc
       61 tgcgagagtg gaagatgttg ggtagcgtca tactgggctt gtgccgttct cggtaaggag
      121 ataccagctt ttccatagca ccattgcgtc agtcccgaac agtcaaagga agtggttgga
      181 gaagaaccac caaacacata tttccaccct tgatatttca acgcttcatt cattaccttt
      241 tgtgccagct ctcccgatac ctgcggaaca gttaaatact gattgactaa ttccacatag
      301 aacatatttc catagccata ccgccagcct ccgttcttcg caacggctat cgggttggta
      361 taggttactt tctttccacc cgatttctca cgggcgaagc tctctgcaag attaaaagtg
      421 tgtttctttc cgtttcctgc cacatagccc acatagccac cgccatagtt ataggactgt
      481 atcgctacat tcaaatcgtc gatatcttga tttttgcagg aagaaagcag ggacgcaaaa
      541 tacttacacc cctgcttgat tgagctttcc gtatctaagg aactaggcgg taaaccaaga
      601 ctttctgaac tctgcataac atcttctgcc gtaccgccac tttctacttg aatgatagcc
      661 agtagtacat tgacgtactc ggagataccg ttttctctgg cgtatttttc taccatagtc
      721 tgatgtttca aaacttctgc ggataagttc atacccgtaa tgccagaaga aaagttgctg
      781 ttttcgtcgt cgctgtccgc actaatcagc accccaaaga aaagcaccag agaaaagaga
      841 ataggaaaca gacttccaat gatagcgata tgtttcagtt tcattttttc ttctgtcctt
      901 tcttcgttac aagattacgg attttctctg tggtctgctg gttcttctgg acagtctggg
      961 tctgctgaac ctttgtccta cggtctttgg tgtaattctg gcgtgtttcc tttgacacgg
     1021 taactttttc tacattctgc ctatatgtcg attgggtcgc tttcccgtca ggagtactag
     1081 aagatagcgg acgttctttg acaccgcttg tcttaactgg ttcgcttgct ttcgtagtcg
     1141 gagttgtggc agggcgtttg acttcctgca ttttttccgc acccgtcttt gaaacggttg
     1201 aagctgtggc tggtcgctca tggggacggg tagctcccgt tgtcgctgat ccgtcagcct
     1261 ttcgctgtgc ctgccttgct tcttgtgcct tttgaagctc catacgcttg acagcgatac
     1321 ttttcttatg ctgttcctgc ttttccaagc gtcccgtctg tctggactgc tgttcctgca
     1381 ccataccacg cttgaaatca gacacgctgg actttgcctt ttcctttgcg gaatacaccg
     1441 cataagcggt ctgtgtgggc atatccttga tattctcttt gacagcgttt gccttgtctt
     1501 tcactttatt tttcgtatct aagacagcac ccacctttga gcctgcacgc tgtcccatac
     1561 tggaagtggt attgccccga ttttctttag aagccgtatt ttttctttcg gctctcttgc
     1621 cagcaacggc acttccagct accgcaccag ccacaccgcc cgaaataccg ccagcactta
     1681 cagcccttgc aatacggtgt tccatacgcc tagcccgatg tcgcatgaac agatacggtc
     1741 tgcggaatat cctgcgtccc atgctttgac tgtcgccagc gttgagagaa aacatactca
     1801 ttaagtcgcc cagcttcata tagataccag cgaaacatac tatctgcaag aacgccacca
     1861 tgaaaaacgg atagtccgtg gatatgttat aaaacatact ggaaatgcta aacgcaaccg
     1921 ttacaatgag cgttattcct gcccgtgtca ttatggtatt aaataccctc acgattgcct
     1981 gctttgccat gctttcatag ctcggtatca tggaaagtag aaagctgata ggtaaaaaca
     2041 tagcgaagat aataaaaagt atctggctga acaacatcat acccgtaagc aagaatacaa
     2101 atatcgtaat accaagatta aagaacaaga ggaagaacac catacctaaa cggtttacca
     2161 cctgcggtat cgtcagattg ttgttgtcgt tgtcctcgat ttctgttttc acgacttctt
     2221 ctctggtctt tccgtcctcg tcctctggac ttgccgatac gagagcttcg acacggtctg
     2281 tcccgatttc ctctgcgttg ctgtttccaa actgtaagag tagccacggc tgttgtactt
     2341 gaatagaaaa taggctgtcc cgtatcaagt ctacgctgtc cttgccctcg ctgtcagagt
     2401 tggggagcat gatttttgtt cccaaatcaa gcgaagcggt actgatgtct gatgaaaatt
     2461 catttatctt cttgatgtag tcgggagcgt aggcaataaa cgaagcggac agcacgaaca
     2521 ccaccacaaa gttgataaca gcgtgaagtg ccttgctggt ttcccgtttt atcagtcccg
     2581 tataggcaac atacattccc accactaaga taataagaag caggaaacca acatagaagc
     2641 ccgtagaaga aaagccgttc tcggtaacgc ctgcaagggt ctgtatgctt tttccgatac
     2701 tgtctgccat atcgttaata aaatcaagtt tataggcttc ctgcaccaca tagccagttg
     2761 cattgcttaa ataaaggctt atcgtccaga caaagttggt aatgcagtaa agcccgtact
     2821 gtaccgattt tccgataccg tccagccagt tccacggaag ccacgaccag ctattatcga
     2881 cgaaaaaatc aagctggtag ttggaaagcg gatattttga atatagattt tctgcgttta
     2941 tggtatcgtc cacaagcccc gtcgcatgag ccaccgtccc cagaagtgaa agcaggataa
     3001 gggaaagtgc caccacgaac agagccattt tgagaaagtg aagtatcttc ctttttgtga
     3061 acgcactctg tatcctttct ttcatcactc cacctcattt ctctgtacgg gcggtctagt
     3121 atcaaaggcg tgtagtaatt cttcaaagac tgggtgtatc tgcaccacac cgacacgccc
     3181 gtataagtcc tgcaataaac attgtccgtt ctccaaatca cgcaagcgtt tctggttgtt
     3241 ttcgtcgtcc ttgtcgatac cgaaaaattc taaggtctgc tttatctcgt tgatgtcagt
     3301 agaacgaaat gcaaacttca aaccgatatt gtttttcaga ctttcctttg acacgtcata
     3361 ggcagactgg gtaacgaaat aaacgcctgc ctgcatagct cgtccagcac gaaccagctt
     3421 atttgatagg gtttcgcctt gtgccacatt taagaacgcc cacgcttcgt ccaaatctac
     3481 aatcttaaaa atgcttctgt ccgaatggat aaaatcaagg gcaaaggtac taatcacaat
     3541 cagcatagac accgacaata attcaatggt cgtgtattcc tcaaaagtgg tatctttatc
     3601 tggcagtaca aggtctgcta cttgaatgat attgagctgg ttatcaaggc ttatagcatt
     3661 ttctaccgtc ccgtctgaaa acagcaggtg tgcaaagtcg tagtccgtga agctgtcgat
     3721 atggtctgcg atattgcgtg agatagcggt atcttctttt ctcaattcct caataacgtg
     3781 taacagtcct ctattttcac tctgggtaac agaacgcacc gcttttcgta acacggggaa
     3841 tttttcgccg tccctagagg aaatacccgt aaggaatgtt aagatgtcga ttgccagact
     3901 ttcagcgtct ttcacattct tcataatcac aaatgggtca agaagtcctg cattgtcctt
     3961 gtcgctggta aggtttacga tattgatttc atgggctatc tctgggagcg tttctttcca
     4021 gttgccacgc tcacttttag ggtctaacag aagtgcttga ccgccaaaca gcaccgcata
     4081 atatacaagt agattgttgc agaatgactt tccaccgcca agacttccca caaaagcaga
     4141 agcaagggca ttagtaactg tgccttttac tccctgcgaa gctaaagacg gttgcaggta
     4201 cacatttctt cccgtatcaa cggaatagcc catatagata cccgtgtttt cccctaactg
     4261 ctgggtcgca ccaaaaccaa gcccagccaa gaagtctgac tttacatact gcacatagtc
     4321 attgatatat cgcttgctgg caggtaaaaa ttcagaatga agtcccaaca tatcgccagc
     4381 aggacgcacc agttttacat tgaggtcgtc gtaaaagtcc ttgacttcat cacaacggcg
     4441 tttcagctcg tcaagatcgg gtgcagacac ccgtatgacg tagcttaact tatacatact
     4501 ttctttgctc tggtctaaat cggtttccag ctcgtccacg ctgtctaaag cgtccaccac
     4561 atttgagctg gtttcacttc ctgcttgata ggcgtgatta tccaaatctt tcaattcctt
     4621 tttcttgttg cggactgtcg ttaatgcctt acggttctcc acgatttcta cattcataga
     4681 agtatcaacg gggaatgtga attgctgttg ctggaaatag aagatttcag aggacggaaa
     4741 atccaactcc ccgacaatta cattgacggt aaaataggac acatagcttt ccttgtcctc
     4801 atgttccaat cgtaaatacc gctggctttc ctcaatcaca caccttgtcg gacggataag
     4861 gtcgtagtat tttatcagcg tttctttctt caatttcttc tttggtagct ggtactcata
     4921 atcttcatag gcgataccgt ccctgccgta aagatgttcc atgagatacc caaaatcatg
     4981 gatttccaag cgacgcacct taaagcgacg ggagatttta ttttccagta acttttccat
     5041 tttcatgtaa cggttgattt catcattcgg catggaaaca aaatcattca tcagcgtgtg
     5101 gttcacttca tgaagaaatt ccttgaacgt cagccatgcc gattttttga tgttcttcag
     5161 attgagctgt tcttccgtaa ccatgagctt aaagccaaga aaaaagcggt agtccacttg
     5221 attgtcccca atcattgata ctaacgcttc ggtctgttcg tctatttttt ggactgccac
     5281 ctcacgaagt ttgcctgtta ccagtttctt tgactgctcc tgcatacttc taatggagct
     5341 ttctgtggca atctgcaacg catgaatttt tccctcacgg gactgtgcga ttagctgtcg
     5401 aaaactgtca tgcacgataa atttctgctc tgcggataga aaagaatagt tgtacggtat
     5461 catctcatag taggcgaaca cctcattgtc cttgttccag acaaggttat tgtcaatata
     5521 ttttatcggg aacatagttc acactcctta ctgccgtgat tgtttcattc aatatctgct
     5581 tatgcagttt tacggctttt cctgcataag tgattttagg tcgcaaggca taggttatct
     5641 gtgatttcaa aaagctgtac ggcttctttc cgtcaaaggt tttctgcgac ataaaccaag
     5701 tgagagcaac gggaataccg aagtatttga gaaatgctcc ctcaatcatg gaaagtgggg
     5761 gcatatcccc aaacagaatg atgataaatt ccgtaatcac aaaccatgta atctgtgtaa
     5821 aggtaacggg aaagggtaag ttaaagtcat tgattgcata taagactttt tccacgttcc
     5881 agatacccgt gtagctttta atctttttca agttctttca gcccctttcg taagttcttc
     5941 aaagagaaaa ggacagccat tttcagactg tcccttaaag agaaatacgc tgtcagtagc
     6001 aacaatgctt gttgctgatc ttccagcgtt aatatggtat ctcacagata cctcggcttg
     6061 tttcaatgaa tcgaccaccc atatccaaat ctcgcccgta ggcttcatag tcaatatagt
     6121 tctgtaagtt agctggaatg tccccaagtg cgttcaattc gtctatgtag tagtaggcaa
     6181 catctgtcat ggtttcacaa tcgggataaa aataaatatc gtccttatgt tccacgactt
     6241 cttccagcgt cccatagtgg ctgataaatt cgtccagaca ctctacgata tagtcgggaa
     6301 gttcctctat catttcatac atttcattga gttcttcaat ggaaacatat tcccctatgt
     6361 cgataggaaa gttgtcggta tcatggacag cgtattcttc gtactgttca ttcaagccga
     6421 ttttttcttt tacatcttcc tcgtcaatag ggaaagtgaa ccacgcaccg actaaatatc
     6481 cctcattgta tctgccaaga ttagcaatat aaaccgccat atcatcaatc ataagcacca
     6541 cctcatttcc tattctggca gttcaaagat actgttttcc gttacaagat agcgtttgtt
     6601 ttcaagtaag tgagaagcgt aggcttcaaa atcgaaatag tatgcttgac agtcctcgga
     6661 taaatgtttg aatgtcgggt cgttcatcag cttttgcctt gcaacatcta tcatgctttt
     6721 acagtcgtga taaacggtaa tcacgttcct gcaaatataa agtgcttcta agttctcaaa
     6781 cacggtaaga agttctacat attcttcctg catatcggct gatagctggc ggtacataaa
     6841 atctaattcg ttaagctggt acacgctggt gtgttcgtgg acttcatcag cataaggcaa
     6901 caccttttcg ataatgcggt aatcttgact ttctgcaccg acacctaact tttcttcaaa
     6961 ctctgcaaca tctatcggta agtcaaacca gtatgatgtt gtttcttcgc catttgttct
     7021 tcccgtttcc accagtaccc ttgtttcctg cattgttcct cacgtccttt ctgttgtttc
     7081 atcacatctt ttaaggtctg gtatgacata ccaaacacat atttagaaaa atctttcaac
     7141 tgtttttctt catagtcggc agggttcagc cgtttcattt catgccacac cttacgcttg
     7201 taagagggca ggtcggaaat gtattcacag ccgacttttg cctgcatatc tttaaaaata
     7261 tcgttcattt catcactcca atctgaaatt taggtaagaa aaaagcagtc aatcctaaga
     7321 ctaactgctt tgtgtgtaag tatgaatttg tttaagtgta actgatttac catgtgtact
     7381 cgtaaagttt actgtatgtt tgacttttaa ataaatatat acaatcaatc atttgtaact
     7441 tgccgtcttg ttcaaattta cttattatca gattatcttc atagatatat gctaagaaag
     7501 tatcatactc tgcatagtat ttttctctaa aaagatttga ctctctaaaa tctttttcta
     7561 aagcaattct tatactgtct aaagcatatt taaagttata acaagtatta aaactaaact
     7621 tgtatggaaa aaagaaaaat aagtttttct tgaaagtaag caatttcaca taggtttgta
     7681 tatcaaattc aatcgttcca tactcatatt tctctgtaag acaagaatgt aaactttcac
     7741 aatcataatc ccgcaacgaa gcaaataacc tagttacagt catttgtgta tttggtcttc
     7801 tcggtggaca cttaccaatt acaccatcac agaatttctg tatttgacca gtaagttctt
     7861 ttgaagcatg aagtcttgtt gtgctttcaa gtaatttaaa gtccatttga taattaggtg
     7921 agttacaatc acattctcca tgattttcag atttaggtgg tacatattct gcaaaatttg
     7981 atttttctct aaaatatatt gatttattaa ctaattccaa caagtatttt tcataattac
     8041 aattttcttc atctttaata aaatttttgt ttatgaatac tgcatgtaaa atatccactc
     8101 tcatttcatc tgaaatcata agcactttta ttcctttcaa aaaataattt atcgtaccca
     8161 cattataaca ttctcatatt acagcaacaa taaaattcgt tatgctccaa taatcttatt
     8221 gaacagctct aacagtacat ctttcacacc gccagcgttg aatactaagc cgacagcaat
     8281 aagggcaact accaagaagc caataagttt tgaaaactca cgcttgaacc ctaagtagat
     8341 accgataacc acaatcgcca taagcactaa gctctgtgca tttgataaaa accattgata
     8401 caaattttgt ccgaaattca tttaattgtc ctcgctttct tctaattgtt tcatttcata
     8461 gtcagcttct ttgctgatac tcaaaataca catcaagact acgccgatac ccattcccat
     8521 agataccagc aggaagtctt ttactaattc ccacattttt tatcactcct aactttccac
     8581 caaatctttt gcaggggtcg tctgctgttt gattatcatt tcatgctttt cactcaagat
     8641 tgcctgcttt tcaatcgttt ccatgtagtc tgtaccgttt cccttatcaa tctttttcag
     8701 cattttcaag gtcggtgcta cctgtctttg tacccaacgc aatgtgcggt ctaaggtgta
     8761 aggttctggt tttgtcgtca gtttcagact ttgccgatta tcgccaataa accaagccca
     8821 gcggtcattg agtttccagt catttttccg cttgtctggt tcttcatcaa taaaccgcac
     8881 atactggttg atgatagaaa aagcggtctg ctctgcgtca tagtaggtca gcaaatctcg
     8941 tactgcatag taagcacgtt catttctaag ccgtatctca aaacggttga taatgtcggc
     9001 ttcttccaga ggtgtaccta atttgacata ctgctcatag tccttttcat agatacagaa
     9061 atacacatct gatttcagcg aaccaagata aagggtactc cccatatatt ctctgtcgtc
     9121 ctctctgtgc ttgataagct cgcccgactg gtaatactta tagcttctgg actttccgat
     9181 atattcccgt ttcctgcatt tctccgcaag ctctggaata tccaaaatgc ccgtatggtc
     9241 gttgatagca aggtcgatac gcttcataat gcctccgtct atgagtgcgt ccataagaaa
     9301 gtcataccag cttctttgct gtgccagcag gtaactttca aactgcctgc aaccccgacc
     9361 ctttaactct aaaaggacac ctttttcttc gtcagccgac gtatagataa agatgtcccc
     9421 taatgaataa tgctccgtat aactgtaatg tccgtaatct tcatggagca tataattgat
     9481 attcagtttt aatatgtctt tgatgatgtg ctgtatatcc agcgtgggaa aacgaatttt
     9541 cacataatca aacagcatgg taagcggtgc ttctggattg aaccttgcca gttctttatg
     9601 caaagtttcc agaagttctt ttgacggctt catttttccg ctttctatct tgtttagata
     9661 ttcccttgtg ataccagaag ctaccgccag cctgccttgt gagataccgt aagcaatccg
     9721 cttctcccgt aattctttta tccattgttc ttcattcaga accatacccc caatctgtca
     9781 agtgtgaagt tttttaaggc gacttcacag ccgatttttg ctaggaaacc atgccagaag
     9841 ccttatgttt cctatgtttt tttgtctatt gtctatttgc aaacgtaccc ctctgttaga
     9901 taccgagggg ttttacctgc tggcgtggct tacgccacac cagcaacggc tagtccgagc
     9961 cgtcgccttt cgcttcgcac gtcgccgtcc cgtcctgcct tgcttgtgca agaaaaccga
    10021 ttgtctgcaa aaaatcatgt cctttcggga ctaaaggcgt gtaaaattca cttatgacgc
    10081 ttgttcccac atcacaatag ccacgccctt tgatacgctt ttggaaaaac tgctttttca
    10141 catctgaacc aaacagcata ccgtaaccta actcgctgat acgccccaat cccacacgta
    10201 aattgaagtt atctctgata ccgtccgaga aatattttgc gtctggacgc tggcaggcaa
    10261 cgataaggaa ataacctgct tgtcgtccta acatgacgat tttctttaac tggctaagta
    10321 agcccacact ttcttttgtc cccagcattt caaaaaacgc cacatattca tcaaagataa
    10381 gaaagcaggg tggcagtccc agataggcgt aattttcgcc cgtcttatag ttcgggtgtc
    10441 gtttcatttg ctcgcttcgc tgtaccatgc cctcataaaa agcattgaca cagtctatca
    10501 tttcttcttt ggtgtgatac acgtttccca tgactgttcc caagtctgct aagtccgcat
    10561 ttttcgggtc taagatgtaa aggacagcgt tggtatgcag tagggcttca atgagcgtca
    10621 gaagaaaata tgttttaccg ccaccagtcc caccagcaat cagagcgtga gggagtgcgt
    10681 catattccca gacaagattt ttcatcagtc taagacagcc gttctctgcc cgtacttcat
    10741 caatggtaat gcggttcgct atcatatcat aaagcagggt atattcgata tagccgtcat
    10801 gcagggtctt gtcggtcagc tcacaataca agccactttc caatttatcc tctaaccgta
    10861 aaagctggtc ttgatatttc cccagcgtaa tttcacagcg gatatgaagc agtccctttt
    10921 ccatttgata ataaatcttt ggaaaccaga cgattttttc ccttgatctg ctttgcaggt
    10981 cagtaaaaaa aacgctgtct tgtacggtat cagcttcata ccacttgttt tccagtatca
    11041 ttcgtgccag cttttgacgg tgcagtagct ttttgaaact gtcgtaacag aagcggtaat
    11101 acagaaaagc gaccaatgca caaacaccag tcgctatcag tatggttatg aagttgtaaa
    11161 gggaaagcgt aaagccattg tctaataagc tgaaatgttc ccagtcggta cgcatgagct
    11221 gttttgtatt taatagcagg ataaccgcta cgaacacaaa caggagtgtc cccattgaaa
    11281 agcgatagac aaggttctta tcgctggctc tgatacggtg tcctttgttt aaaatcattc
    11341 tcataaatca atcactcctt tctgggtatg aaaaaagcag tcaatcgtat agactaactg
    11401 ctttgtgtgc atggatatga agttgtcaaa ctggaattta acgttcactc atatattgtt
    11461 ttatttcatc agaagtcaat tttcgtactt ctgtatgtgg atattcttta tactctccaa
    11521 cattaaacac aggtgtcatt tgtttgcatt tcttgtcttt attctttttc aagaatagat
    11581 gtaaatcctc attcccggcg aatattttat aagatactct gcctttactg ttctctatct
    11641 cataaatacc acatgaactt ttcgttgtat aatcggctgt tcgtaaataa agttttgcaa
    11701 tttccaatga cttaaaagga aaattccatc tttgtaatcc tctgtttggg tcatgttcaa
    11761 tacaaatgca acgtccacaa gttccacaaa tatattgagt gtggttttct aagcagtcca
    11821 agggatttag taatggtgtt attctatttt catcagagta acattcttca cacatttttc
    11881 ttttcgctcc ttatcaaatt ctaatttgtc gctttcttca tacccatatt ataacagttc
    11941 cgtatatcct ctacaacgaa aatctattca gcaagtctat tttttcggtt gtccctgcgg
    12001 tgtatggttc tgtgaagtgc ctgtgttctg attgccttta ttcttcagta caatatcttc
    12061 tgcctttaca taccagtcca catctgcacc cgtataggtt tttcgtgata ccgtatcggc
    12121 tacgggattg acaagctcca cgactgcatt gtaaggaaat tcccttaacg gtacttctgg
    12181 cggtacggac acggggataa ttccaccatg cagactgcac ttcaaatcat agatacgctt
    12241 tttaagctgg gtactcggtg tcccgtcctc attttgcaag aacacatcac gcaccgctgt
    12301 aaattttaat tctccaaatg ttttctcttt gtcaatgaca aatccatttg ataatctcat
    12361 aaattcttca ctcctttact tttcttcaac tgctacaata tcatcagcta ctaatacata
    12421 atcggtatgt cccacatccc cgattgcgta ccctctgccg tataacttcg gattgacaag
    12481 ttttactttc tgttcatact tgaaatgctt ttcgccagcc tgcacgggaa tttccaccac
    12541 aacattttcg cctttctgta cgtcagaata aaggttatag cttcgtctgg ctatgacctt
    12601 gcggttgttt ttatcccttt caaagatagg ctcgctttcg cctgcaaatt caagagttcc
    12661 aaaagactgt gccatatctg gcacgacata tttcatttcc atattgtttt acctcgtttc
    12721 tttctatatt tgataagttt atgattgtaa ttttttattc tggcttgtct gccgtttgac
    12781 agtttcggcg gagaacgtga tttttctttc atcataccgt taccgcctta tgattttttc
    12841 attgtacggc gtttgtaaag atatgttcca gccagtccac cagcagatgt aagcaacatc
    12901 acaagaaatg ccatgacatt tgtactgtcg cccgttttag gactgtcgct aggtctgttt
    12961 ggcttttctg gtgtctgcgg tgtttcgagt ttctctggga cttctggttt ttcattaaaa
    13021 gtaatcgtct gtccctcgtc ctcaatatcc ttatgctcgg taactttctt cggctcgtct
    13081 ggattgctta aatcatacaa ttcttcaaaa gttacaagct gtttgccgtc aagggaagta
    13141 gcgtcaaagg taaaggcaac ttccgctttc atagtttcgc tgtcagcggt aaaggtgtaa
    13201 tcactttcca cacgtttccc attgataaga agttctgcat tttcttcttt caacatctgc
    13261 cagcctacaa gtttgtactg tgtaccgact tccaagccct ctaaggttac ggtatcaatg
    13321 attgtaacgt cttttccagc ttcaatctct ttgttgccgt ctttgtcggt agcagtcgta
    13381 tgtatcttga tgatacgttc tgtaatcaat acagtttgtc cgtcgtcctc aatgtctttg
    13441 tgttccgcaa ctttcacggg ttcgtctgga ttgcttaaat cgtataattc ctcgaatgtt
    13501 accagatttt taccgccaag ctcggacgca ttgaatgtat aagaaatttc cactttcatt
    13561 tcttcatcat cagcgataaa agtatagtca ttttccacac gttttccgtc aatgataagc
    13621 tctgcatttt cttcctttaa catctgccag cctttgagct gatattttgt accttttgta
    13681 agcccgtcta atttgacagt atcgacgatt gttacctctt ttcctgcaag gatagtcttt
    13741 tcgctgtctt tgctggtcgc tgtggtatgg atagagattt ctttttcgta ttcatcagtc
    13801 aaagtcccta aatcaatcac aaggttattt cttgatacca cgatttcaaa aggtgggata
    13861 agttcaaagc ctttgttact atcgcaacgc atttcttcaa tgatgtaagt atcataaggc
    13921 aatgcacctt tgctgtcgtc tgcttcagaa gttccaaacc acacaccgtc ctcgctggtc
    13981 ttgcctgcgt tagtattgtg cttatgagaa gtccattcag cagaagtgga gaattgcccg
    14041 ttatcatcag taactacaac atgactttct cccgtcgtct tgcttgtgat cctaaaggga
    14101 acatcagcaa gacgcttgtg tgtgcctgca ccgattttca ctccctcaat atccccacgc
    14161 ttaatctgat tgtagataga gtgggcttcg tcggttaagt ccacgatttt tccattctct
    14221 gtgattgcaa agtcaatcgg cttcgcaccg tctgtcaagt aaccgtcggg agcttcactc
    14281 tcaacgatac ggaatttccc ataaggtaaa aggtcagcag aagtagaagc cacaccctca
    14341 atatctgtac gaattgtctt taccacttca tttttcttat atagcttgcc ctcaaccaaa
    14401 acagaattgt catttaagga aatgacgtca aaagcagtat ctttcaaagt ggcacttcct
    14461 tgtggtttgg tatcgctcgt ttctaaatct cttttctgaa ttttcacacc gccacggata
    14521 accttgtctg atacggaaaa ctggttactt cccgtcaata cagcaaggtc gccgtcctct
    14581 gtaatttgtg taaggtataa gccttttatc tgttcagact tatcgccagc ctgcatatat
    14641 gcaccgtcca gcaagtagcc gtttggagct tttgtttcct caacagatag tgttcctaaa
    14701 ggaagaatcg ctttgccgtc ctgcatatag aagctgtcgc cagatacctt gtaagcgtcc
    14761 gctaattttg tgatgtagtg agttgtcccg tcactgtctg tttcagcgat tgtctttgta
    14821 acccatgtac gagtagcttc ggcagggaga ttgtctttgt tatagaagcc agcataatac
    14881 ttccatgtaa actctgcacc ctctaaagaa gcgtttccct gcggattgtc tttctgcgtt
    14941 tccatatcaa tcttgaaaag ctcaatcaag gtgtccgtta cttttggtgt atctgatacg
    15001 ttcaaggtcg ctgtctttcc agcttcaact tttaaggaat acacggttgt atcaacttta
    15061 tatcctgctg gtgcggataa ttccctaata tagactgtac ctgcttttac ctctacaaca
    15121 tctgtatttc cgtttttatc agtcgtaagg gtggcaagct gtttcgtgca gtccttatca
    15181 gaaaagacac cataggtcgc accagcgatt gagtaattcc cgttaccgtc tgtaatgctg
    15241 gtattactgg aagtcttttg cagttttgca tttccgacat ttaacttcgc ccagaattgt
    15301 cccaattcct gcccctcgcc agagtagata taaccgccac attcatagcg tcctttattt
    15361 tctttcacaa aggctttagc accagcgaaa acttcgtcct gagttgcttt tggtatttca
    15421 tcataagaag ctcgcacgtt gtcgcattgc cagccaagat gtacgctcaa tctctgccag
    15481 acaacacatt gttccaacag atagacttgc ttgtagttca attccttgtg tgcttcgcca
    15541 tactgtttga catactctaa ggataacgcc acatctgaaa tctggtcggc actcatacgg
    15601 gtgcttgcgt cagctctggt cttgtagcca ttcttaaaat ctgtattgat gtctatacag
    15661 taagcgtcct cgccctcaac agtcaaatgt ccctcgttaa aggtagaacc aatcgaaccg
    15721 tcattcatta ctttttctac gataccgaca cgttcctctg attccgtcca gtattgcttg
    15781 ctttctgcat ggacggcggt actcggtaaa gcagtaacga cagtcgcaaa ggcaagtact
    15841 cccgtacaca atcgtttcaa tatctttttc ataattctaa atgctccttt cattttgggt
    15901 aaaaaaatag acgctcaata ttgaacgtct tacattgaaa agggatactt tttacaagta
    15961 cccctcaaat ctaatattta attgtttgtg ttcccacact ctatatcaac aactactgaa
    16021 acattgatat agttttttat ctctttattt ctgattttat cgccctcgct cgtaaagact
    16081 atatgcttaa aaaagtgcct aaaattaagg atttctacat agttcgtctt tgtagcaaca
    16141 cacaagtctc tatatgtgta gaatgaggga acatatctac aggttgtgcc tcaacacatt
    16201 taaatccgtg aacatttaga taatctaaat cccttgctaa agtagaagga ttacaagaaa
    16261 catagacaat tctttccgga ttcattgaaa caatagtctc taataccttt tcgtcacatc
    16321 cctttctagg tgggtctaca acgactacat tggcagtctt accctctcta tacatcttag
    16381 gtacaatttc ctctgccttt ccaacataaa attcagcatt atgtatattg tttaatttag
    16441 catttatctt agcatctttt atggcatcat ctataatttc tattccataa acctttttag
    16501 ccttttgtgc caaaaataaa gatattgtac ctatcccaca gtaaatatca aaaacagtat
    16561 cagtatcatt taaatttgca tattcaagag ccttatcata caatacttta gtttggacag
    16621 ggtttacttg gaaaaatgat aatggtgaaa tctcaaacac taagtctcct atataatcgt
    16681 ttatttttcc atctccatat ataactatat tttctcttcc tagaatagca ttcgtatctt
    16741 tttgatttac atttacaacc aaagtcttaa atccaggtat attttcctta agcactgaag
    16801 ctaattcttt aagatatgga agtttgtttc catttgctac taatacaacc attacttctt
    16861 tagttgtaaa acctattttt gttactaaat gcctaatcaa ccccgtgtga gtcttttcat
    16921 catatatgct taccttatag gcccttatat atgtttttat tattttaaca attttatcat
    16981 ttatctcatg ttgtattacg catttttctg tcgatattac atcatgagtc ttctttttat
    17041 agaagccaat aattggaata ccattattct tttgtattgg aaattgtgct ttatttctat
    17101 atctatatgg attatccatt cctatagtgt catgaacttc tacatcctct aacttaccta
    17161 ttctcgaaag tacttgttta acttcatttg ttttcatttc aagttgttta ttataatcta
    17221 agtcttgtat ctgacaccct ccacaatccc taagattgtc actacacact cttttcaccc
    17281 tgaatggaga cttttctatt atctcaacaa tatctcccac agcataattt ttctttactt
    17341 tattaatcct aactttaact ttatcatgta ttaatccgcc ctctacaaaa actgtaatac
    17401 cattgtactt tcctactcct actccgcctt gaccaatgtc tactatatct acaatataca
    17461 tctcgttttt cgaaagcata aatcaccctc caatcaatct attatattta aatctttaca
    17521 aacttttttc tttaaattta tattaaaata ttgctattaa ttaaactata ttttttacta
    17581 agctacaata ttttatttta ccaaaaaaaa aggagcttat aaagcccctt agtaaataaa
    17641 tttattattt ttcttataaa actctagttg aacctctata taccacgcct cttgatgcat
    17701 ccacagttac aacttctcca tcttttacta gatttgttat atcagctgca gacacaataa
    17761 ctggtatatc taaatttata cctacaatag ctgtatgtga tgtcattcca ccattctcag
    17821 ttactacagc tcctgctttt tctatataat tgttcatttc agcatcagta gcagtagaaa
    17881 caagtatgtc gccttcatta aagtctacac aagcatttcc attctttatt atacgaactt
    17941 taccttctac tgtttgagta cctacaccta taccttgcac gatttcttcg cttattacat
    18001 gaacctttat taaattagta gttccactta ctcctactgg tactccagca gttataacta
    18061 ctaattcccc attatctata taatcagctt gtctagctgc ctcaattgcc ttttctataa
    18121 cttcatctgt atttcctgca acagaagact taactggata tactccccat gtaagagcta
    18181 atttattcat agtcttttca ttatttgtag tagctattat tggagatttt ggtctgaatt
    18241 tagataccat tctagcagta tatcctgaag aagtagatgt tattatagct gatgcattta
    18301 aatctactgc tgttgtacaa gttgcatggc ttattgcatc tgttacagta acattgttag
    18361 taccattttc ctttagtaat ctatcataat ctaaagtctc ttctgttctt tttgctattg
    18421 tagccatcat ttttactgcc tctacaggat attttccagc agcagtttct ccagataaca
    18481 ttatcgcatc tgttccatca tatatagcat tggcaacgtc tgtaacttct gctcttgttg
    18541 gtcttggatt tcttatcata gaatcaagca tttgagtggc agtaacaact ggctttgcta
    18601 attcattaca tttttttatc atcatttttt gaactattgg catctcttca gttggtatct
    18661 caacacctaa gtcacctcta gccaccatta taccatcaga aacttttaat atttcatcta
    18721 ggttctctac accttcttgg ttttctattt tagatattat ttgtatatca gttgcattat
    18781 tgttctctaa tacttctctt attgctagta catcagatgc ctttcttaca aaagaagcag
    18841 ctatataatc tattccttga cttattccaa actctatatc acttatatct ttaggagtta
    18901 ttgctggtaa atttatctta acaccaggta catttactcc tttatgattt ttaactattc
    18961 ctgaattttc aacaacacaa actatatctt ctccatttat ttcttttact cttaagccaa
    19021 ctaaaccatc atctattagt atagaatctc ctgatttaac gtcttcagca agacctttat
    19081 agcttactgt acacatttct ttagtcccca taatatcttt catagttata gtgaactttt
    19141 gcccttcttc taaaaatacc tctgggtctt caaagttacc tgttctaatt tctggacctt
    19201 tagtatctaa taatatagca actggcttat ttaatttttc tctaactttc tttgccatat
    19261 caattctttc tttatgttct tcatgcgaac cgtgagaaaa gttaaatcta cacacattta
    19321 gaccattttg cataagttga gttaaaactt cctcactttg tgatgctgga cctagtgtac
    19381 aaacaatttt tgtcttcttt acattattta acatatttgc tcctcctgag atattattcc
    19441 acagatttat ttttaatact aaaacttata tagataatat ttttgccatc tcataagctt
    19501 ctttatcaaa tactttcttt tgagctaaag cttcacttat ttctaaatca attattttgt
    19561 tttcttttat tcctacaact ctagctgatt ttccatctaa taataattct actgctctta
    19621 ctccaagtct acttgctagt attctatcag atacagttgg gcttcctcct ctttggacat
    19681 gccccaatac agtgactctt aaatctgctc ctgactcttt tttaagttcc ttttctaaat
    19741 cactagcact tccgactcct tctgctaaaa cgattatact atgtctctta cctctttttt
    19801 gagtagtctt taatcttaga gcaacttcat ctactgtaat ttctacttct ggtactatta
    19861 tagtttccgc tcctcctgca agacctgcat ataaagctaa atctccacag tgtcttccca
    19921 taacttctac tatgttaact ctttcatgag atgatgatgt atctcttatc ttacctatag
    19981 catctataat agtattcatt gcagtatcaa atcctatagt ataatctgta tatgctaaat
    20041 cgttatctat agttcctggt atgcctatag ctgggaatcc taagtcacta agtttttggg
    20101 ctcctgcaaa tgaaccatct ccaccaatta caactaagca atcaatttta tactttttaa
    20161 gaatttttac tgcttttaat ctaccttctt ctgttttaaa ttcttcacat ctggaagatt
    20221 ttaatatagt tcctcccctg tgtataatat ctccaacaga agataagttc atttcagtta
    20281 aatcttcttc tagtaatccc ttatatcctc tattgattcc atatactttg catccataat
    20341 atattgctga tcttacaacc gctctaatcg cagcattcat tcctggagca tctcctccac
    20401 ttgttagtaa tcctatagtt ttcatttttt acctccttgg attttatgtc aattttttat
    20461 tataatcatt gttattgtat tctaatggac tttttttgtc cctatatcac tttttaatcc
    20521 catcaagact aaaaaaatta aatgtcctta aatgtccatt ttgtgatatt atatcacaaa
    20581 acggacaata tttttcatat tattataata tatttagatt tttatataaa aaatcaagct
    20641 tttactttta tgttatcttt aggaagtaac tcttctaagt tatttataaa ttcatcacat
    20701 atacaagtca atgccccggt cattttatat gctttacgtt taccatttat attttcatcc
    20761 atagggtata agtatatact gtcattacct ggatattgtt tggctatttc tacaatatta
    20821 ttagttgtat cagtatcaga catactatct attttcaaat acaatttttt accactttct
    20881 ggcttaatat tttctacatt tctagttctt cctgaattgt agtttctatc tgcaaagtca
    20941 gtatcatcat ttatatcttt tatctctcta gctataagtt ttgcattttc gccttctttt
    21001 atacttaatg ttccttttac atatattata ttatcttcat tcaaaatgac attatacttt
    21061 tgtaataatt gaggaaaaac tattatttct atagcaccat acaaatcttc taattcaata
    21121 aatgccataa tttcatttcg ttttgttgtt ttaatagttt tagttacaat cattccaccc
    21181 attataacat ctgtttcatt catttgtagg tatgactctt cttcctcttt taatgaattt
    21241 aattttccat tatccataga tgttttttct tgtagttctt tttcaaattg tgataaagga
    21301 tgtccactta catacattcc caagacttct ttttcaaggt taagtctctc tctttcttcg
    21361 tactcttgcc ttttaggcaa actgtatatt tgttgaaaat cactatcttc ctcactatct
    21421 ccaaaagcat caaataaaga aatttgacct tgaacatttt tctttctatc catagataca
    21481 ctttctaata aactttcata accagccatc agactagctc tattttcact tatattatca
    21541 aaagctccac attttattag actttctatt actctcttat ttgtatcttt ttggtctaat
    21601 cttttgacta aatctactaa atctacaaat aatccattag attctctttc agcgattata
    21661 ttgtttatta tatttacgcc aacatttttt acggctgcta gaccaaatct tatattgtcg
    21721 ccttcaactg aaaactttga aaaacttttg tttatatctg gaggtaatac atctatttct
    21781 agtgctttac attctcttat atactcaact accttatcag tatttcccat tacactggtt
    21841 atcaatgctg ccataaattc aactggataa tatgttttta gataagctgt ctcatatgct
    21901 aaaaccccat atgcagctgc atgtgattta ttaaatgcat atctagcgaa gtctatcata
    21961 tcatcaaata ttttattagc tatttcctct tctacaccat ttctgataca ccctgcaatt
    22021 tctatattac catcttcatc aaatttacca tgaataaaat attgtctttc ttcttccatc
    22081 acgtccatct ttttcttact catggctctt ctaactaggt cacttcgtcc gtaactataa
    22141 ccacctaaat ctctaacgac ctgcataacc tgctcttgat ataccaaaca accatatgta
    22201 acttccatta taggctttaa tttttcatgt agatatgtta catcttttgg gttgctttta
    22261 ttttttatat atgcaggtat agaatccatt ggacctggtc taaataggga tattcccgct
    22321 acaatatctt caaaattgtc tggttttagc tgtttcataa aacttctcat gccagcactc
    22381 tccaattgaa acacccctag tgtatttcct gatgaaagca tttcatatac tttcgggtcg
    22441 tcataatcca tctttgaaaa gtctattttt tctgtgtaat tttttataac tctatttttt
    22501 tctattaaat caagagtatc tcttataact gtaagagttc ttagcccaag aaaatccatc
    22561 tttaaaagcc caagttcttc aagtgttgtc atagtaaact gtgttgtgat tgcatcttga
    22621 tgtttgtaca aaggtacata ttcatctacg ggattttttg atataacaac tcctgctgca
    22681 tgagtagaag catgtcttag cattccctct atctgttttg atatatttat tatttctttt
    22741 gtttccgggt cttggtcata caattcttta agattaggat ttgtatctag ggccttatct
    22801 attgtcattc ctaaagcaaa tggtatttcc ttggctacct tgtcaacttt attgtagcct
    22861 atatccaata cccttccaac atctcttatt gcagcttttg cacccattgt tccaaaagtt
    22921 attatctggg ctacatggtc atcaccatat tttctcttta cataatctat aacttcttct
    22981 cttctctcat aacaaaaatc tatatctata tctggcatgg atatacgttc tggatttaaa
    23041 aaacgctcaa ataatagaga gtactttatt gggtctatat cagttatttt aagtgtatat
    23101 gctactatcg aaccagccgc actacctcta cctggtccta ctataatatt attttcttta
    23161 gaaaaattta taaaatccca aacaattaaa aaatactcta cataacccat tttttcaatt
    23221 acatctaatt cataatttaa tctctctagt atctcattac taggattatc atatctctct
    23281 tttaatccat taaaacacaa ctcccttaaa taagtttctg gtgtatatcc ttctggaaca
    23341 tcatacttag gaagatgtat agtattaaaa tcaaactcca cattacacat atcagctatt
    23401 ttcacagtat tgtcaatagc ctctaatgca tatggaaata attcttccat ttcttctctt
    23461 gattttaaat aaaactcatc actaccaaat ctcattctat ttgggtcatt taatgttttt
    23521 cccatttgaa tacacataag tacatcatgt attttcgaat cttctttatt tacatagtga
    23581 acatcattag tagcaactag tggtatacca gtctcttttg ataattttac taaaccagag
    23641 tttacttctt tttgctcagg taaattgtga tcttgaatct ccaaaaagaa attttcttct
    23701 ccaaatatgt ctctgtagtc aagagcaaat tgttttgctt tttcataatt tctattcatt
    23761 aaagcacgtg ctacatctcc tgcaaggcat gcagaaagtg ctataatccc tttgttatgt
    23821 tttttaagtt cttccatgtc aactctaggc ttatagtaaa aaccttctac gtatgaagtt
    23881 gaaactattt ttattaaatt tttatatcct tccatattct tagctaacag aactaaatgt
    23941 ccttgatatt tgtcatagtt tgggtcttta tctctcaatc cacgtgcagc tgtatagact
    24001 tcacacccta taattggctt tattccttct tttatagctg ttttgtagaa atctataaca
    24061 ccaaacatac aaccatggtc agttatagct attgagctca tgtttagttc cttagccctt
    24121 tttataagtt ttttcaccct cgaaaaccca tcaagtaaac tatactcagt atgtacatga
    24181 agatgagcaa aatctttgtt cattaaatca cctcctgctt tataatttta attttaccac
    24241 aaatatatgt cctaaaacaa aaacagagac ttttatctca aaataggaat taacttcaac
    24301 atataccatt atatgttata aattaatgct tattctgaga ttgtcccctc aatttattgc
    24361 tatgattttt ttttcaaatc tgttgcaatt tcttctattt ttctaagtct atgattgact
    24421 ccagattttc ctattggtgg ttctaacatc tctccaagtt ctttgagagt catatcctca
    24481 tactcgattc taatcttagc tatctcttgt aaattttctg gcaaactgct aattcctata
    24541 gtctcttgta tgagcttaat attttctact tgtcttactg ctgcatttac tgttttagaa
    24601 aggttagctg tctcacaatt tactatcctg tttacattat ttctcatttc ttttactatt
    24661 ttagtatttt gaagacttaa aagagcgtgg tgtcctccta taatactcaa caaatctgat
    24721 atttgttcac tctctttgat ataaacaacg tgattatttt ttctagccac aattttacta
    24781 ttaaaaccta aagagtttat aagttctttt agagaatctg caaactcctc attattagtt
    24841 acaaattcca tatgatagtt cttttctggg tcgcttatag aacctccacc aagaaaagct
    24901 cctcttatga aagctctctt acatccttca tgcttaatta agttctctga aattttgttt
    24961 atagtaaaaa atccttcttt atcttcaagt atacctaact tttttaataa catttctgaa
    25021 cccatttcgc ttgttaccat taatacataa ctgttatttc tctttagcat ttgattctta
    25081 tttactgaga ttgtagtatt gatattaaaa ttctttttta ataatttaaa tactttacgg
    25141 gctattgaat ttaactctgt tgttatcttt agatttagct tcttatatcc aacaatttgt
    25201 atacttcccc ctgatttaac tagagctgac aattcagcta tattacaaca ttcattccca
    25261 gatataactc ttgctagttc atttttggtt tcagttgaaa aagacatatc tatcacctat
    25321 taactaattt ttctttaacc ttttttttat ttcttgtaag gcaaccttta ttatctcctt
    25381 ttcatcatca tacctagcta agtctactac tctatctagg tggataaatt tagcatcaat
    25441 aaagccttcc tctttttgtg gaatagtatc catattcttt gcttgcatca aataccaaaa
    25501 aactgtttta tgaactgctc tattttcatc ccagttttct ttgaatgtat agtgtatttc
    25561 acctaaatat ttcaatatat ctgcttttac tccagtttct tcacttactt cacgtaatgc
    25621 tgcctcttgg ttattttccc cttcttctac ttttcccttg ggtaacaccc aatctccatt
    25681 gaacttcctt agtaaaagaa tcgtattgcc aaacaggact acaccaccag cactaacctc
    25741 ttctctcatc gatgttcact ccttaaaact aacataatga taaggatttc tacacaattt
    25801 tttaaaatcc ttttttacta acttttgttg taattatgat ttagggctaa ctcaataact
    25861 atgttagata tatactttgc atcatgtctt atataattat tttttatttc aattaaattc
    25921 ttctctacag tttttatacc catctctttt aatttatctt tttgcttttt atctaacaag
    25981 acttgctctg ctccatcttg tttatataag tcaagcattt cttctggcaa tatctcatta
    26041 tttgcgatta cataatctat taaattctca tcagtgtgtt ttactatagc attaacatgc
    26101 tctaatacat tgtacccttc tgtctcacct ggttgagtca ttatatttgc tatatatact
    26161 tttggagcta cagacgattt aatagcgtct acaatcccct ctacaagtaa attgggtatt
    26221 atacttgtat ataaacttcc aggacccata attataatgt cagcatcata aatagatgca
    26281 ataacatcct ttaatggttt tacatctttt ggatttaaaa aaattttatc aatagagctt
    26341 ttttgaattt ttgactcttc aggtatacta gattctccat ttattatatt gccattttct
    26401 aatttggcaa ctaaatttac atcttccaaa gttactggta aaactcttcc tgttatagca
    26461 aaaatttcac ttaatttata tacagctttt tcaaagtttc catacaaccc attcatagca
    26521 gccaaaaaca aatttccaaa actctgacct tttaaaagcc cttctgtaaa cctatattgc
    26581 ataacttcat tcattgttgg ctctatattt gcaagtgcta ataaacagtt tcttatgtct
    26641 cctggtggga gcattcctaa gtcttctctc aatacacctg aacctccacc atcatcagca
    26701 acagttacaa ttgcagttat attttgcgta gtgtgtttaa gacctcttaa aaataccgat
    26761 tgaccagtac ctccacctat cacaaccaca tttggttctc tattttcaac aatagacctt
    26821 tgaaatagtt ttactttttc attttttgct tttttatata taaataacga tacaattaat
    26881 gcaatccaac ctaaaattcc tacaataata agtaatttag ccatgtttgc ctccattatc
    26941 gcaacataga gtctctatgt ttctttacaa ctctatatcc cttattagat aaatcctccg
    27001 ctataagatt tgttatagta actgacctat gtcttccacc tgtgcatcca acaccaatta
    27061 ctagatgttg ttttccttcc tctatatatt gaggtactaa aaaatgaatc atatctaaaa
    27121 gtttcacata aaattcttca ctgattttag aattcataac ataatctcta acttctttat
    27181 catcaccagt tttagctctt aactcttcaa cataataggg atttggaaga aatcttacat
    27241 caaatactaa atctgcatca gcaagtatac catgtttaaa tccaaaagat actacagaaa
    27301 tagttaggtt tggattatct tcacctgaag aatatatttt ctttatttct tccttaaggt
    27361 ctttaggttt catgttagtt gtatcaatta tacatgtaga taactccttt aaaggttcca
    27421 ttatctttct ttccattttt ataccttctg gaatctgcat atcttttgcc aatggatgat
    27481 ttcttcttgt cattttatat ctctttaaca atacatcatc attacaatcc aaatatacca
    27541 tttcatattc ataattttct ttttctaaat aatttaagct ttcatgaagc gcttcaaaaa
    27601 actttctccc tcttatatct atccctagag caactttatc aatacttgaa tttggttgat
    27661 aacataattc tgcaaattta gttatcaaag caggaggtag attatctaca caataaaatc
    27721 ccatatcctc taaagctctc attgtctcac tttttccaga tcctgaaaga cctgtaacta
    27781 taacaaattt cattgctaac tcctcccttt tatcttatgt ttattatatt ataatgtttt
    27841 ctactaacga tatatccaga ttagagtcag atatagtctt catagctagt tcaaaatcac
    27901 caactctttc tggacaatgt gcatctgagc ctattataaa tttattttct agccctttta
    27961 ttttatttaa ttgatttaca ttcaaaaaag aatggctact atttatctca agtctagtat
    28021 ttgtcttttt tgctgtcttt gctacttctt ctatatacac atcgccttta tctcctggat
    28081 gagtaattat aaaaatatca ttattactta tcgcatttat tacagctttt gtattatatt
    28141 cttttgcttt ttcagtttta aaaatatagt tattacaatg atttaataag cttcttaatg
    28201 atgttggagt agaaccaaaa tgatatccag ccataatata atcaaaatct ctaataaatt
    28261 tatcatccat atctatattt cctttatcat ctaatatgtt acactccata cctaaaagta
    28321 tatttatatc agtgtactta tcatttaaat aatctacttc ttctctcatt ttgagaatat
    28381 cttttttctt tacaccatat gcaatatgtt tataactatg gtcagatatt cctattgttt
    28441 ttattccttt agaaatggct acctttacat tatcctcaat agtccctttg ccatgactat
    28501 ataatgtatg tgtatgataa tcagccagta ttttcatttg ttaatcctct ccaagtattt
    28561 tgacttcttc ttccaacata accccaaact tggcatatac agcacttttt ataacatata
    28621 ttaaatccaa aatatcttta gcacttgctt ctccttgatt gactacaaat ccacaatgct
    28681 tctcagatac ttgtgctcct cttaaagtaa gacctctcaa tccagtttct tctattaatt
    28741 tacctgcaaa atatcctgtt ggtctcttaa atgtacttcc tgcactagca aaatttaatg
    28801 gctgtttagt tattcttctc gtcgctaaat catccattaa actttttatt tcatcataat
    28861 ttccttcttg taattccaat tctgctgata aagctatata tccgtttttc gatattatac
    28921 tttttctata cccaaattcc atctgttcat ttgataattc aaatatattg ccttccatat
    28981 ccatcagtct tactgacttc actatgtcct tcatttcacc accatatgct ccagcattca
    29041 tggctaatgc tcctcccaat gtgccaggta ttcctgatgc aaactcaaac ccttttaatt
    29101 cttgcttttg gagagctttc cctaaaactg ataataaagc tcctgactga gcagtcatcc
    29161 tagtatcatt tatctcataa gaattgaaat tatcagctag ttctattacc actcctctta
    29221 ttccaccatc tttaattaaa atgtttgaac catttccaat tattaaatac ggaatagatt
    29281 cttcttttac caacttaagt acatttttta attgttcttc agttctaggt ctaactaata
    29341 tatctgctgg tcctcctacc ctaaatgaaa tatgtttttt cataggttca tcgactttta
    29401 tatcctcttt acttaatata tttaataaat ttatatatat atcttgatta ttcattgtat
    29461 ttcctcccaa attatactga actttagctg tcattattat ttaaattaca ttagtatata
    29521 gtattaacta tattcaataa tatatgattt tgcttatcat atggatttta tattttaagc
    29581 ttcttaatta caaactatat tcaataaata tataataaag taaaaaaaaa aaaataacaa
    29641 catataaaag aatataaata atttaaaaaa agcatcaata tcactgatat caatgcttta
    29701 aaaggcaatt taattcgtat tatttatcta actatttttg acatagcaaa gataataaat
    29761 ccctccaact actatggaac ctccaacgat atttccaagc gttacaaata ccaaattagt
    29821 tataaattga accatagtta tatttgctcc taatgccatt cccattggta taaaaaacat
    29881 gtttgcaaca ctatgttgga atccacataa tacaaatagc attattactg tccaacatga
    29941 agccaatttt gacattatat cttgagatgc tgtagccatc catacagcta aaacgactag
    30001 aatattacaa agtattgctt ttaaaaacat tgatgctata gttgaattaa ccttagcttc
    30061 tgccacagct atagcttttg tagctgcatc tcctgtcaat gtagaagaat aaaacacaag
    30121 tgcaactagc aaaattgaac ctactaaatt tgcaaaataa accagtcccc agtttcttaa
    30181 catttttcct aatgttattt ttttgtccat aagtgcaata gccattaagg tgtttccagt
    30241 gaataattct gctcctgcca ctactacaag cataagacct actggaaaga ccatagcact
    30301 taaaaagcta gctacccctg ggtctatctt gccaaaagtt tgactaacta tcatactccc
    30361 caatgcccca aaacctataa atgctcctcc aaataaacct aatagaattg cgttttgtgt
    30421 cgaaatattt gcttttttaa tgcctgcact tatagttgct tgtgcagttt ccccaggtgt
    30481 caagaatcct ttactcataa atccttcccc cttaaaaatt atactttccc ttgtcttttt
    30541 atggcaataa ttatataata acaatatgat atataataaa ttttattaac ataaaaaata
    30601 tactatatac ttatatatac ttgtctcata taattatact atttattata taacaacttt
    30661 gttaatttcg aaataattta tattgaattt gaaaaattta ccttttgatt atttatttta
    30721 ctttttaatt attg
//
LOCUS       DAEPHU010000051        30577 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 01A10CD0081
            SAMN05941466-rid12468953.denovo.051, whole genome shotgun sequence.
ACCESSION   DAEPHU010000051 DAEPHU010000000
VERSION     DAEPHU010000051.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941466
            Sequence Read Archive: SRR6291087
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 30577)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 30577)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068158.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 22:43:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,892
            CDSs (total)                      :: 3,805
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 87
            rRNAs                             :: 8, 1, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 55
            CDSs (without protein)            :: 55
            Pseudo Genes (ambiguous residues) :: 0 of 55
            Pseudo Genes (frameshifted)       :: 21 of 55
            Pseudo Genes (incomplete)         :: 28 of 55
            Pseudo Genes (internal stop)      :: 16 of 55
            Pseudo Genes (multiple problems)  :: 8 of 55
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..30577
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941466-rid12468953.denovo.051"
                     /strain="01A10CD0081"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            32..1144
                     /locus_tag="KR231_002384"
     CDS             32..1144
                     /locus_tag="KR231_002384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5009 domain-containing protein"
                     /protein_id="HBH0004751.1"
                     /translation="MNSRIKSIDIIRGLSIALMIVCNNPGTWMRMYPQLRHAVWHGVT
                     LADFAFPFFVISLGVTIPISINSKLKNNKSTLSIILSIFKRSILLILFGFFLNYLGNP
                     DLDTVRILGVLQRMGLVYFVTSLAYLLLKKLNVGSTATIITFLCIATFIIVGYYILAK
                     PYGFELEGSLAQLVDLHFFKGHLYKPEFEPDGFLTSIVAISSGMLGCTMGCVLLKENL
                     GEYKKFFKILVMSIILLIGAFIFNQYFPFNKRLWSSSFVLLMAGSYGILLSIFYFICD
                     IKNKSKIFTPIIALGSSPIFTYMCLEILSHVFWNVPKLTNKVDYPTTLVEWTTYELIT
                     PWAGTTWDSLIFSLLYVLFWVIVMSIMYKKKIFIKI"
     gene            1398..3422
                     /locus_tag="KR231_002385"
     CDS             1398..3422
                     /locus_tag="KR231_002385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HBH0004752.1"
                     /translation="MKKTTKLLATGMLSVAMVAPNVALAAENTTANTESNSDININLQ
                     RKSVVLGSKSNASVKFKEKLNADSITLNFMCYDMPLEATLNYNEKTDSYEGVINYNKD
                     PEYLNVWELQSIKINGKDEQKVLNKEDLESMGLNLKDYDVTQEFIISDANSTKAVNEY
                     MRKTSAPVKKLAGATRFETAVEISKQGWKDGSSKVVIVNGELAADGITATPLASTYDA
                     PILLANKDDIPESTKAELKRLNPSDVIIIGDDGSVSQKAVSQIKSAVNVNVTRIGGVD
                     RHETSLLIAKEIDKYHDVNKIYIANGYAGEYDALNISSKAGEDQQPIILANKDSVPQG
                     TYNWLSSQGLEEAYYIGGSQSLSSKIIDQISKIAKNGTSKNRVSGADRHETNANVIKT
                     FYPDKELSAMLVAKSDIIVDSITAGPLAAKLKAPILITPKTYVSAYHNTNLSEKTAET
                     VYQIGDGMKDSVINSIASSLSKHNAPTEPDNSGSAAGKTVVIDPGHGGSDSGATSGLN
                     GGAQEKKYTLNTALATTEYLRSKGINVVMTRDTDKTMALGERTALSNTIKPDLFTSIH
                     YNASNGAGNGVEIYYKVKDKNGGTTKTAASNILKRILEKFNMKNRGIKTRTLDNGKDY
                     LYVLRNNNYPAILVECAFIDNKSDMDKLNTAEKVKTMGTQIGIGIEDTVK"
     gene            3642..4328
                     /locus_tag="KR231_002386"
     CDS             3642..4328
                     /locus_tag="KR231_002386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
                     /protein_id="HBH0004753.1"
                     /translation="MSGYTNDECEIPKIKSYPGADKEIASEIDYSIVKGTVLFDLYQR
                     IMDLVLSIIGLVIGLPLIAIFGILIKIEDKGPITYKQERLGKCGRRFYIYKLRSMRTD
                     AEKFGAQWAEKDDPRITKVGKFIRKTRIDEIPQLFNILKGDMGLIGPRPERPNFTVQF
                     NEEIPGFINRLAIKPGLTGWAQVNGGYEITPEEKLKEDIYYIKNRSILLDFKILFKTV
                     KVVLTGDGAR"
     gene            4423..5478
                     /locus_tag="KR231_002387"
     CDS             4423..5478
                     /locus_tag="KR231_002387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp7"
                     /protein_id="HBH0004754.1"
                     /translation="MIKKISTILSLVLLISISSTIGVFADANPKRELIEGSIPEISTE
                     LNKRAFKDSKEVILVNEESIVDSISATPLAYAKNAPIVVTKSKNLGRVTRNYLKELGP
                     EKVTIVGGLKAVSKDAERNIEKMGMKVERIRGKDRYDTSLKIAREMYRTVGFDEAFLL
                     SSTTGLENAISVYSYAAKSGMPIIWAKDEGFEEQIDFLKGKNLKKIYALGDSKEFIAE
                     IDSNLKNIEGIKQINKSSTNVDLIKKFYDEKDIKKIYTARLDFGSRSDVNEYISLGVV
                     SAKENMPILICSDNLSRAQDKFLKDSNINDVVEVGYTVGDYSLFKSIFNLTFLSCIVL
                     ILLLLLITFRALRYESK"
     gene            5593..7149
                     /gene="murJ"
                     /locus_tag="KR231_002388"
     CDS             5593..7149
                     /gene="murJ"
                     /locus_tag="KR231_002388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="murein biosynthesis integral membrane protein
                     MurJ"
                     /protein_id="HBH0004755.1"
                     /translation="MSKTAKAALWIMAATMFSKVLGFLRELVLANFYGTGMYADVFVL
                     TLNIPGLIIAVIGSAVATTYIPMYFETKKRLGDEGALKFTNNVLNICYIMAIVIAIIG
                     LLFTEQFVTVFAAGFRNDPAKFQAAILFTKIMISGVLFLSGSKIFSSFLQVNDSFVIP
                     GLIGIPYNIIIIAAIALSAGKNVWILPAGALLAMASQLLFQLPFAFKKSYKYKPYINL
                     KDESIKELVNLVLPMLVGVAVGQLNIFVDRLLATTLGDGKLSALNYANRLNEFVMALF
                     VTSIITVIYPKLAKMSGKDNKEGFISTIVKSSNCIILVVLPISIGAIILAEPLVRILF
                     QRGKFDALSTDLTSIALRLYSLGLLACGVRDVLYRAFYSLSDTKTPMINGSIALIINI
                     VLNLILIRPLGHAGIAISTSTSNIITVILLFISLKKKNGYFGGDKIIKTGLKSLVASG
                     VMAVATLLIYNNLYAFMGSGTIKEIISVGAGVLGGASVYTVLIVLFKVEEMDLAFEFL
                     RKGKQKLLRR"
     gene            7195..8901
                     /locus_tag="KR231_002389"
     CDS             7195..8901
                     /locus_tag="KR231_002389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-sugar mutase"
                     /protein_id="HBH0004756.1"
                     /translation="MDYKNNYEMWLNSPYFDEQTKNELLSIKDDEKEIQDRFYKNLEF
                     GTGGLRGIIGAGTNRINIYTVRRATLGVLNYIMKTQGEEGKQKGIVIAHDSRYMSREF
                     CIEVAKTLSAYGVKAYIFEELKPTPELSFAVRYLKCAMGIVITASHNPKEYNGYKVYD
                     SDGGQICIDMANDIIAEVNKIDDYSTIKSIDFEEALSKNLITILDNEVDDEFIKAVKK
                     QVLRQNIIDEYGKKLKIIYTPIHGTGNKPVRKVLNECGFENVMVVKEQELPDSNFSTV
                     KYPNPEEKSVFNIAIEMAKNNGTDLIIGTDPDCDRVGIVVKDSSGEYVVLNGNQVGSL
                     LVRYILESLVEENKLPKNNPTIIKTIVTSELGAKIAKAYNVDCLNTLTGFKFIGEKIK
                     AFEESNDRSFIMGYEESYGYLIGTHARDKDGVVSSLMICEMAAYYSSKGMNLYEALID
                     TYNKFGYYKEDLKSVTLKGIDGIKKIKEMMLYFRSVKIDNVADVKVDKILDYKDGVDD
                     LPKSDVLKFLLEDGSWIAIRPSGTEPKIKFYFGANSDNQEDVEFKLNNLISYILNVVD
                     SI"
     gene            8923..9996
                     /locus_tag="KR231_002390"
     CDS             8923..9996
                     /locus_tag="KR231_002390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannose-1-phosphate guanylyltransferase"
                     /protein_id="HBH0004757.1"
                     /translation="MKVYNVIMAGGGGTRFWPLSRQEVPKQLINLSGEDALINETINR
                     IDSLAKKDDLFIVTNEKQLEALKDIVKDKCLDSNILPEPCARNTAAAIGFAAFNIMKK
                     YGDGVMCVYPADHYIKDEKEFKSILEKAIYIAENNDKLVTIGITPTFPSTGYGYINFN
                     RENTIEDVAYEVVEFVEKPNYEIAKEYVNSKKYVWNSGMFVWKVSKILEDFKRYLPKV
                     YEKLEDISKYLGTKEEMEKIKEIYPTIQSISIDYGIMERSNDVIVVPGDFGWNDVGSW
                     DSLGAIYPTDDEGNIKRGENITIDTKNSIIYSDDKLISTIGISDLIVVSTNDAVMVCR
                     KDKAQDVKKIVEQLKEEDRQEYM"
     gene            10008..10730
                     /locus_tag="KR231_002391"
     CDS             10008..10730
                     /locus_tag="KR231_002391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HBH0004758.1"
                     /translation="MIPKKIHYVWFGGPKGNIENICINSWKEKLPEYEIVEWNEKNFD
                     IEKEIKGNKFLEECYKRKLWAFISDYTRIKVLYEQGGVYMDTDMQILKDITPLLENNR
                     LVCGYEDDREYINGAIIGVEKGHPFLKDLLEYYEKEVLTSSLFTIPKIMTHLMEKNYK
                     KIDPNNYEEGIRVYDKEYFYPFGFKEDFTPECITENTFGIHWWGKSWAKKRNYFLESK
                     HLTGVNKIWKCCKIFASNTLRS"
     gene            10746..11903
                     /locus_tag="KR231_002392"
     CDS             10746..11903
                     /locus_tag="KR231_002392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897937.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide polymerase"
                     /protein_id="HBH0004759.1"
                     /translation="MKTLNDDRNIMIRKYLYIFVLFIILLRKYMISFIDPNMDIGMIK
                     SALFYSSIGILMLLFLFDKRKSITEMVLVGVCVLLYLLNREGAILLIVLLAVSAKQID
                     DKFIVKNYLIISACFLMVAILLFNLFPSLIFNQEVHYRYIEKIDMLVTRMDFGLGNPN
                     SVFYHMVTIYAAYIFLRYKDYNKWDRILLFGSAFFVYQTTYSRTGFFTILAGLIFVEI
                     IRWIDIKKIKGLPMLLKTLPVILTLFSVIIGTVFDKSTLLNRLLASRPKFWNVYLAEK
                     GNFLKPFGNSYSPAIKATNPLDSSYVYIISVLGVVACILFMYLMYKGIESFIEKDKKA
                     YLVALFIFLLYSFAENLLLEASFSFAVVLLIKEVILNDKREIDLWKMKSRR"
     gene            11906..12745
                     /locus_tag="KR231_002393"
     CDS             11906..12745
                     /locus_tag="KR231_002393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HBH0004760.1"
                     /translation="MLISLIMPTLNRYDDIYLLMDSLENQTYKNFELIVVDQNDNSKV
                     KEIVDKYIDKLDIKYIKSSKKGLSYNRNVGIDNAVGQIIGFPDDDCVYENDTLEKVIN
                     FFNKNKDYKIYSCKTMDSNKVDAFKKMYDGTCDITSSNVLDTITSITFFIDFEGKDYT
                     RFDEKLGVGGEFGAGEEIDYVLNLLSLGFKGKYFGNDIIYHPAKKHSKSKEKYQKDYN
                     YGRGFGALCKKEIVYRKNYKFAKVMVSKLVRNIGGLILSSNRDYHSATIKGRINGFRQ
                     YKL"
     gene            12760..13935
                     /locus_tag="KR231_002394"
     CDS             12760..13935
                     /locus_tag="KR231_002394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-glycerol glycerophosphotransferase family
                     protein"
                     /protein_id="HBH0004761.1"
                     /translation="MDKVKFLINMLLAFFIYPFNKHKFNGRDIWLIGGHSGDIYNDNS
                     KFFYEYMLKEHNDVETYWVVNKDSKVFDKIPGKKLIRGSVENYLYYYNSKAIVFSHAP
                     SADIAPYNFAVPVLNYFHKKTIKVFLNHGTISFKKRKPMNKKFKNIIDNLYKSYNIVT
                     ASSEFERNVMVNDWGMLDDSVYIIGNARYDNLPTNEVAQTRDILYTPTWRDWIKFSSG
                     KFTDTDYFKNIMNFLNDDKLNKILDEKDINVKIYMHHLMHEFIDDIKENITGKRIVFL
                     DKGVTLANEIRKSAANITDYSSVAIDFLYMNRPILFYQFDLDEYMEKVDSYIDLKSEM
                     FGSLAYNNDEAVNKLIDIIENNFEVMDNQKNERNKFFRYNDNKNCKRIYDCVLSKIK"
     gene            13964..14713
                     /locus_tag="KR231_002395"
     CDS             13964..14713
                     /locus_tag="KR231_002395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HBH0004762.1"
                     /translation="MKKNLVSIITPMYNSEKFIEATIKSVLNQTYQEWEMLIIDDCST
                     DNSPNIVKSYMQQDSRIKCIKTETNKGVSNARNLALSKATGQFIAFLDSDDQWNSSKL
                     EKQVNFMLENDYVISFTSYELMDENDKKLNKVIKVPPNVDYRRLLKGNILGCLTVVID
                     KSKLDFEIRMSGVRHEDYVLWLSILKKGHIAHGINEVLALYRKSSNSLSGNKIKAAMW
                     TWNIYRNIEKIPLYKAIYYFINYGINGIKKS"
     gene            14735..15643
                     /locus_tag="KR231_002396"
     CDS             14735..15643
                     /locus_tag="KR231_002396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HBH0004763.1"
                     /translation="MYKYKFTVFTPTYNRAHLLENLYNDLKAQTYDFNDFEWLIVDDG
                     SSDSTKELVEKFISENKLNIRYIYKENGGKHTAINLGVKNADGELFFIVDSDDGLIKD
                     SLEIANDEWDSLENKEGFSGVVGLCVYPSGDLIGTEMPEDKKICHFADLYFKYGVKGD
                     KSIVFVTDELIKFPFPERKEVRFLPESVVWNEMSKYYKVICVNKPMIIRDYLDDGLTK
                     NILSKNALRGRALEFLYLINQNTYPLSRYPYMWIKNYINLARYSLLSDSHYFGELRKV
                     SDKLLYLALFPLGYYKYIGQRKLVSK"
     gene            15691..16443
                     /locus_tag="KR231_002397"
     CDS             15691..16443
                     /locus_tag="KR231_002397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HBH0004764.1"
                     /translation="MNEPLVSIITPVYNSEEFLSETIKSIQNQTYKNWQLLLVDDCSK
                     DNSSEIIKSFRKEDARIKYIKLEKNSGAAVSRNVGIKNAEGRFIAFVDSDDLWDSRKL
                     EIQIEYMLKENVGFSFTSYRYMRQDGSKTNKVARAPKKIDYEGLLRNTIIGCSTVVID
                     KEIVGEFSMPLVRRGQDTATWLQLLKKEKYAYGIQEDLVNYRLVGNSISSNKIKALKR
                     TWNTYRNVENLSLPKSLYVFCFYVFNAIKKRV"
     gene            16421..17764
                     /locus_tag="KR231_002398"
     CDS             16421..17764
                     /locus_tag="KR231_002398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose/GDP-mannose dehydrogenase family
                     protein"
                     /protein_id="HBH0004765.1"
                     /translation="MPLKKEYKFYILGGKKMKIAIAGTGYVGLVTGVCLAEVGNENVV
                     CVDVDEQKVKSMKLGIAPIYEEGLEELMVKNYNRGRIDYTTDYKKAYEDVDVILIAVG
                     TPERSDGSANLDYIKVVAKQIAETVTKDTLVVIKSTVPIGTNEEIEDYINRNLKNDVK
                     VELASNPEFLSQGTAVKDTLHASRIVIGVESEWAREILEEIYKPFNQPIIVTNRNSAE
                     MIKYASNNFLALKISFMNDIANLCEIAGANIEDVALGMSYDDRIGSKFLKAGIGYGGS
                     CFPKDTKALHWLSEHNGYELKTVKAAIEVNESQKLKLVRKASKLVESFQDMKVAVLGL
                     TFKPDTDDIREAPSIPNIKYLLERGARVTVYDPIGVNNTKKIFGDSILYADSVDDAIE
                     DAEICFIMTEWKDVLNYDIHKYKEKMKNPLVLDGRNCYKIKDMEELGIEYYSIGR"
     gene            17770..18861
                     /locus_tag="KR231_002399"
     CDS             17770..18861
                     /locus_tag="KR231_002399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HBH0004766.1"
                     /translation="MKTVCYLADGSNPHTLKWCSFFKNKGYDIHVISLNGGHMEGIKI
                     YNFGSNVEELKNENISKKTGYLGSIKQIKKLVNEIKPDILHAQYASSYGFIGSLLGYH
                     PYIISVWGTDIYDFPNNGFIQKQIIKHNFRKADYIFSNSRDMAKEANKYTAKHVDVTF
                     FGVDMDRFKPMEVEKEDAFVIGIIKSLEKKYGIEYLIQAFKMLKDEYKDKKIILKIGG
                     SGSQMDNLINLAKELGIENDVQFLGRISPENVSKTFNSFDVTVFPSLREGFGVAAIES
                     EACEVPVIVTNVGGHPESVWENETGLIVEPKQPEEIKNAIIKLMENDELRLNMGKKGR
                     QFVRENYEVNLNFNDIEKIYDSIFDKYKK"
     gene            18945..20858
                     /locus_tag="KR231_002400"
     CDS             18945..20858
                     /locus_tag="KR231_002400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728921.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HBH0004767.1"
                     /translation="MRESIDLEKESFFNRLFKKYKFRHLTLLILDICSVLVAFRMSLS
                     LTGNLNAFTTNDIIISVCIYIVLHIVSFRLFKCYNTLWRYAGEEEIISIFVATLAYLI
                     PIYIINKLLGFDYPIMFYVLNTIFIIMFTSGARIAYRAIRIVMNKTYSRGKVSNILII
                     GAGDAGEMVIQELKRNPELKKVAVAIIDDDKNKIGRIIHNVKIVGTTSDIKDVVEKHN
                     VDEIIFSIANIEKRRKKEIIDVCKNTNCKIKTIPGIYEIIDGKVDIKQIREVEIEDLL
                     GREPIKTNLREISNYIEGKVILITGGGGSIGSELCRQIAGFNPKELIIVDNYENNAYS
                     IQQELLRKYKNKLDLKTVIASIREEKRMDEIFNKYKPEVVFHAAAHKHVPLMESSPGE
                     AIKNNIFGTLNIAGLSSKYRAKKFVLISTDKAVNPTNIMGATKRAAEMIIQTMNAESQ
                     TEFVAVRFGNVLGSNGSVIPLFKKQIEDGGPVTVTHPDIIRYFMTIPEAVGLVIQAGA
                     MAKGGEIFVLDMGEPVRILDLAKNLIKFSGFEPDVDIKIEFSGLRPGEKLYEELLMSE
                     EGLLDTEHKKIFIGRPIDVDREKITKYLKLLREITNNEEVEKIDGIMRELVPTYIKPE
                     DANIKEIATTREK"
     gene            21057..21764
                     /locus_tag="KR231_002401"
     CDS             21057..21764
                     /locus_tag="KR231_002401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C40 family peptidase"
                     /protein_id="HBH0004768.1"
                     /translation="MMNIKNKKHILKKFIAMVLIAGVVTVEAGAITASAAEPTNSPMS
                     ATVDQCDFLNVRSGASANDAVVGKINTGDKVEVLELHSNGWIKIKSVDNVTGWVNGDY
                     LTIQGGNVDAKVQNVLNLAFKQQGKPYRWGATGPNAFDCSGFTSYVYKNGAGVNLPRV
                     SRSQATVGKKVSRAELKPGDLVFFGSGGSINHVGLYVGDSKFIHSPQTGDVVKVTSMA
                     PGTNYARRLITATRVLQ"
     gene            22066..24177
                     /locus_tag="KR231_002402"
     CDS             22066..24177
                     /locus_tag="KR231_002402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding glycosyl-hydrolase Cwp19"
                     /protein_id="HBH0004769.1"
                     /translation="MKKISILVLSLIMTLTMCSVSSFADSSNDKEMRAAWISTVYNLD
                     WPKTKNNEAKQKKEYTDLLDKLKSVGINTAVVQVRPKSDALYKSNINPWSEYLTGTQG
                     KDPGYDPLPFLIEEAHKRGMEFHAWFNPYRITMADESIDKLPANHPAKKNPSWVVKHG
                     NKYYYDPGLPEVRKYIVDSIAEVVQNYDIDGVHFDDYFYPGVSFNDTATYQKYGKGQN
                     KDDWRRENVNTLLRDVKASIKSIKPNVVFGVSPAGIWRNKSSDPTGSDTSGNESYVGT
                     YADTRAWIKQGLIDYVVPQLYWPIGLKAADYSKLVAWWANEVKGTNVDLYIGQGIYKQ
                     GQSSYGGQNIAKEIVQQVTLNRKYSEIKGSMYFSAKDIANSTSIQKDLKSLYSSSEEP
                     VTPPSNVKVEKLRGDERYDTAVAISKKGWATNSDTVVLVNGYSIVDGITSTPLATSND
                     APILLVNKDNIPTSTKNELKRLNPSKVILIGGNNSIGDKVESEIKDTLSNVSINRVGG
                     SDRYSTSLMIAKELVKTNPVEKLYITSGTGEADSLSIASKAGEEKQPIVLVSKDNVSD
                     EVYNWISDLKVKDAYFIGGNLSISDSVINKLDKVITNDVSKNRIAGENREETNGKVIQ
                     KFYPNAEYSSMFVSKSNQLVDALTSGPLAAKLKSPVVMLGNSVTSAQKTALEPKKTTL
                     VYEAGDGINQNTLNTFLNLVK"
     gene            complement(24375..25340)
                     /locus_tag="KR231_002403"
     CDS             complement(24375..25340)
                     /locus_tag="KR231_002403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HBH0004770.1"
                     /translation="MSKLKKFVILLAFLVVIFPISVYGYFYYKLSAIHDSSISSDLLD
                     NNDHKNEDGIINILLMGTDARPNEDSSRSDAMMILTIDNKHNDIKLTSLARDSYVDIP
                     GHGKQKLTHAYAYGQADLLIQTIEENFNIDIQNYACVNFESFMYIIDAIGGVEVTVEK
                     GEIRELNKFIPETYKWSKSDDKGSIQYIRNSGKQTLNGYQALSFARIRHNDTAFARDG
                     RQRQIIQAIIKKTETLPVTKYPGLLDAVLPYVKTNMKPNAILSLGAQVLKMGDLNIKQ
                     FEFPIDDEIHSTGGIYGKAGWVLRFDPDTLDILHDFIFNDIEFKQ"
     gene            complement(25625..26581)
                     /locus_tag="KR231_002404"
     CDS             complement(25625..26581)
                     /locus_tag="KR231_002404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HBH0004771.1"
                     /translation="MSGLKKFVIFLALLVIAFPVSIYGYVFTKLKTIQDDSINTEALS
                     SNDYKNEENITNILLLGTDARPGEEVSRSDAMMILTIDNKNKSLKLTSLNRDTYVNIP
                     GHGEQKLTHAYVYGQANLLIETIEENFQLDIQNYAVVDFFSFMDIVDALGGVTVTVDK
                     SEIRELNKFIPETYKWNKNDNKGSLKYIRNSGEQKLNGYQTLAFSRIRKNDSTDERDR
                     RQRSVIQSLINGVKDLPVTKYPNLVNTILPYVKTNMNPNEIISLGKELLSIGNLNLKS
                     MEFPLSTENGRKIGNAGYVIPFEEYELDAMHDFIFKDIMVED"
     gene            26949..27737
                     /locus_tag="KR231_002405"
     CDS             26949..27737
                     /locus_tag="KR231_002405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HBH0004772.1"
                     /translation="MIKLIATDLDGTLLDEKSEINPEFYKVFKKLRERGIMFSAASGR
                     QYQNLIKKFEDIKDDMMFISENGTLVVYKGKEILSNPLNKELVNEIIETTRSIKGKKI
                     VMSGKKYAYIESKDEAFIQEVSTYYAKFKIVEDLTKVEGDILKIAVFDFKGAEHNNNI
                     YFEKFSDRAQVCISGVEWLDLTAKGANKGSAIKKVQKMLDIKYEETMVFGDQLNDVEM
                     MKSAYHSYAMENANEHLKQIARFRAKRNTENGVVDKIKEVIKIG"
     gene            complement(27860..28330)
                     /locus_tag="KR231_002406"
     CDS             complement(27860..28330)
                     /locus_tag="KR231_002406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4358 domain-containing protein"
                     /protein_id="HBH0004773.1"
                     /translation="MKKILILFFSIILSLGMVSCSSSGDYKNVSTSKIKKALKSSDLL
                     IKESKIFDAKDFNYFNDVEEDIIQGFVINSSEKLSLEDIIVIKTDEVDKIYKTLENYK
                     KDMIQAPFGEGHGEKINSEIANNTIIEKAGRYVYLISAENATQIENKILNIIKK"
     gene            28469..29113
                     /gene="uppS"
                     /locus_tag="KR231_002407"
     CDS             28469..29113
                     /gene="uppS"
                     /locus_tag="KR231_002407"
                     /EC_number="2.5.1.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="di-trans,poly-cis-decaprenylcistransferase"
                     /protein_id="HBH0004774.1"
                     /translation="MRIPKHVGIIPDGNRRWASQNGMTKDKGYESGIDPGLESYRLCR
                     DLGCEEVTFYGFTTDNTRRPSVQTKAFTKACIDAANILIDEGAALLVVGNTKSPMFPE
                     ELLPYTNRIKAKEGQIKANLLVNYGWYWDLNNISGVENVNKNNIQDYIQSFDVSRLDL
                     IIRWGGRRRLSGFLPVQSIYADFYVIDNYWPDFKSDDIKDAFSWYDTQDVTLGG"
     gene            29156..30061
                     /locus_tag="KR231_002408"
     CDS             29156..30061
                     /locus_tag="KR231_002408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861670.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HBH0004775.1"
                     /translation="MKKKLLDGKITLIICKSVKIYTKKGEEMSKGNNNNNSRNKSKKT
                     SHLNRKKRKLNKKKLAVLICFTVLFLFIAFKATQGVVALVKSMDKSNKTSQQQNVNSE
                     QFDLGNEEENKKKKYTVFIDPGHGGNDKGTESKTSNRYEKDLNLQIAKKLANKLSKQK
                     DIQVVVSRTDDTYISLKDRAILANNSSADVLVSIHLNAEKNGNTATGIETWYRNKATD
                     GSKELAQTVQSTIVSYVKVRDRGIVENNFEVLRESNMPAILIECGFLTTPSEEQKIIN
                     EKYQDQLAEGIVQGVLSYLDSKGNK"
BASE COUNT        12117 a         3314 c         5421 g         9725 t
ORIGIN      
        1 aatttcaaat aatgctgtag attctaaact tatgaatagt aggattaaat caatagatat
       61 aataagaggg ctatcaatag ccctcatgat agtctgcaat aatcctggga cttggatgag
      121 aatgtatcct caattaagac atgctgtatg gcatggtgta acacttgcag attttgcatt
      181 tccttttttt gttatatctt taggtgttac aattccaata tcaataaata gtaaactaaa
      241 aaataataaa tccacactga gtataatact tagtatattc aagagaagta tcttattgat
      301 attatttgga tttttcttaa attacctagg aaatcctgat ttagatactg taagaatact
      361 tggagtactt caacgtatgg gattagtcta ttttgtgact agtttagcat atttactgct
      421 aaaaaaatta aatgttggaa gtactgctac aataattact tttctatgta tagctacatt
      481 tataatagtt gggtactaca tcttagcaaa accttatgga tttgagctag aaggttctct
      541 tgcacagtta gtggatttac atttcttcaa aggacatttg tacaagccgg aatttgaacc
      601 agatggtttt ttaactagta tagtagcaat ttcttcaggt atgttgggat gcactatggg
      661 atgtgtactt ttaaaagaaa acctaggaga atataaaaaa ttctttaaaa tactggttat
      721 gagcataatc ctgctaatag gtgcttttat ctttaatcag tattttccat ttaataaaag
      781 attatggtct agctcatttg tacttttaat ggctggcagt tatggtatat tactgtcaat
      841 attttatttt atatgcgaca tcaaaaataa aagtaaaata tttaccccaa taatagcact
      901 tggaagtagc cccattttta catatatgtg ccttgagata ttgagtcatg ttttttggaa
      961 tgttccaaaa cttacgaaca aagtcgatta tccaactacc ttggtagagt ggactacata
     1021 tgaacttata acaccttggg caggtacaac ttgggattct cttatatttt ctttattgta
     1081 tgtcctattc tgggttatag taatgtctat aatgtacaag aaaaaaatat ttattaaaat
     1141 ttagtgcaat atttttagat gataaagtct ttgatttgtt caaatataca gaaactatca
     1201 aatataatca aaatttctcc tcgataaaat ttaaaaacca tgccataaaa gattacaaaa
     1261 agtttacaat ttgtaatttt ttgtgctata atgaaaaaag atttacataa tattgaattt
     1321 atgtaatata aaacaagctt aagatgtatt aaaaaagatt taaagattta aagaaccaaa
     1381 aaattagggg ggatatgatg aaaaaaacaa caaaattatt ggcaacagga atgttgtctg
     1441 tagcaatggt ggcaccaaat gtagctttag cggctgaaaa tactactgca aatacagaat
     1501 ctaattcaga tattaatata aatttacaaa gaaaaagtgt agtgttagga agtaaatcta
     1561 atgcaagtgt aaaatttaaa gaaaaattaa atgctgattc aataacatta aattttatgt
     1621 gttatgatat gccacttgaa gctactttaa attacaatga aaagacagat tcatatgaag
     1681 gtgtaataaa ctataacaaa gacccagaat acttaaatgt atgggaactt caaagcataa
     1741 aaataaatgg taaagatgaa cagaaagttt taaacaaaga agacttagag tctatgggat
     1801 taaatcttaa ggattatgat gttacacaag agtttataat aagtgatgca aattcaacaa
     1861 aagcagtaaa tgaatatatg agaaaaactt ctgcaccagt aaaaaaactt gctggagcta
     1921 ctagatttga aactgctgtt gagataagta aacaaggttg gaaagatggg tctagtaagg
     1981 ttgtaatagt taatggagaa ttagcagcag atggaattac agctactcca cttgcatcta
     2041 catatgacgc accaatatta cttgcaaata aagatgatat accagaaagt acaaaagcag
     2101 agttaaaacg tctaaatcca agtgatgtaa taattatagg tgatgatggt tcagtttcac
     2161 aaaaggcagt gtctcaaatt aaatctgctg taaatgtaaa tgtgactcgt attggtggag
     2221 ttgatagaca tgaaacatct ttacttatag caaaagaaat agataagtat catgatgtta
     2281 ataaaatata catagcaaat ggatatgctg gtgaatatga tgctcttaat atttcatcaa
     2341 aagctggtga agaccaacaa cctataatat tagctaataa agattctgta ccacaaggta
     2401 catataattg gttatcttca caaggtttag aagaagctta ttacataggt ggtagtcaaa
     2461 gtttatcatc aaaaattata gaccaaatat ctaaaatagc aaaaaatggt acttcaaaaa
     2521 atagagtttc tggagcagat agacatgaaa caaatgcaaa tgtaattaag actttctatc
     2581 cagataaaga gttgagtgca atgttagttg caaaatctga cataatagtt gattcaataa
     2641 cagcaggacc tttagcagct aaattaaaag ctccaatact tataactcca aaaacttatg
     2701 tttctgcata ccataataca aatttatcag aaaaaacagc agaaacagta tatcaaattg
     2761 gtgatggaat gaaagatagt gttataaatt ctatagcatc tagtttatca aaacacaatg
     2821 caccaacaga accagataat tcaggttcag cagcaggaaa aactgtagtg atagacccag
     2881 gtcatggggg ttctgattca ggggcaacaa gtggattaaa tggtggagca caagaaaaga
     2941 aatatactct taatacagca ttagcaacta ctgaatattt acgttcaaaa ggtataaatg
     3001 ttgttatgac tagagataca gataaaacaa tggctttagg agaaagaaca gcattatcaa
     3061 atactataaa gccagattta tttacaagta tacattacaa tgcgtctaat ggagctggta
     3121 atggtgtgga aatttattac aaagtaaaag ataaaaatgg tggaacaact aagactgcag
     3181 catcaaatat cttaaaaaga atactagaaa aatttaacat gaaaaataga ggaatcaaga
     3241 caagaacact tgataatgga aaagattacc tatatgtgtt aagaaataac aattatccag
     3301 caatacttgt tgaatgtgca tttattgaca ataagagcga tatggataag ttaaatactg
     3361 cagaaaaagt aaaaacaatg ggaactcaaa ttggaatagg aatagaagat acagtaaaat
     3421 aaaatagaaa atattaaagc aaaacatatc atctcctgtt ataatgtaaa atataacaag
     3481 agatgatata tttttgtaaa gaatcaaatt gtttacaatg atgtttcttg tattgataat
     3541 ctgctcatta ttgagtataa tatagaaata agtcaaaaat aagatagaaa taagttgaaa
     3601 ttaagaatta aaaaaatttt tattccaata tggaggtaac tatgtctgga tatactaatg
     3661 atgagtgtga aatacctaaa attaaaagct atccaggggc agataaagaa attgcaagtg
     3721 agattgacta tagcatagta aaaggaacag ttttattcga cttgtaccaa agaattatgg
     3781 atttagtttt atctataata ggacttgtga taggtttacc tttaatagca atatttggaa
     3841 ttcttattaa aatagaggac aaaggaccaa taacttataa gcaagaaaga ctaggaaaat
     3901 gcgggagaag attctatata tataaattga gatctatgag aacagacgca gaaaaatttg
     3961 gcgcacaatg ggctgaaaaa gatgatccta gaataactaa ggttggaaag tttattagga
     4021 aaactagaat tgatgagatt ccacagctgt ttaatatatt aaagggggac atgggcttaa
     4081 taggtcctag accagagaga ccgaacttta ctgttcaatt taatgaggaa atacctggat
     4141 ttatcaacag gctcgctata aaacctgggc ttacaggttg ggcacaagta aatggtggat
     4201 acgaaatcac tcctgaagaa aaacttaaag aagatattta ctatataaaa aataggagta
     4261 tattacttga ctttaagata ctctttaaaa ctgttaaagt agtattgaca ggagacggag
     4321 ctagataatt ttaaaatatt agattactaa tcaatgaaaa agctctttaa aaagagcttt
     4381 tttattgtca aaaaatacaa aaaagaaaag gaatgagaac ttatgattaa aaaaatttct
     4441 actatattat cgttagtttt gttaatctct atttctagta cgataggagt atttgcagat
     4501 gcaaatccca aaagagaatt gatagaaggg agtataccag agatttcgac agaattaaat
     4561 aaaagagcat ttaaggattc taaagaagta attcttgtaa atgaagagtc aattgtagat
     4621 agtataagtg caacaccttt agcatatgca aaaaatgctc caatagttgt aactaagagt
     4681 aaaaatcttg gtagagtaac aagaaattat ctaaaagaac taggtccaga gaaggttacg
     4741 atagtaggtg gtttaaaggc agtatctaaa gatgctgaac gtaatataga aaaaatggga
     4801 atgaaagtag aaagaataag agggaaagac agatatgata catctttaaa gatagctaga
     4861 gaaatgtata gaacagtagg atttgatgaa gcatttttac ttagctcaac aacaggatta
     4921 gagaacgcca tatctgtata ttcttatgcc gctaaaagtg gaatgccaat aatatgggct
     4981 aaagatgaag ggtttgagga acaaattgat ttcttaaaag gcaaaaatct taaaaaaata
     5041 tatgcattag gtgattcaaa agagtttatt gcagagattg attctaactt aaaaaatata
     5101 gaaggaataa agcaaataaa taagtcaagt acaaatgttg atttaataaa gaagttttat
     5161 gatgaaaaag atataaagaa aatctatact gctagattag actttggtag tagatctgat
     5221 gtaaacgaat atatttcttt gggagtagta tcagcaaaag aaaatatgcc aatactgatt
     5281 tgtagtgata acttaagtcg tgcacaagat aaattcttga aagatagcaa tataaatgat
     5341 gtagttgaag ttgggtatac agtaggtgat tatagtctat ttaagagcat atttaatcta
     5401 acattcttat cttgtatagt attaatacta ttattactat tgattacatt tagggcactt
     5461 agatatgagt cgaaatagtt tttgatttat aaggaagctt ttcataggtt aaatttactt
     5521 aattagaata atgtttataa gcagttttaa aagttctact tttagagttt aaattagata
     5581 aggagaaaga agatgtcaaa aacagctaaa gcagcattgt ggattatggc agccactatg
     5641 ttttcaaaag tattaggttt ccttagagaa cttgtacttg caaatttcta tgggacaggt
     5701 atgtatgcag acgtatttgt attaacatta aatatacctg gtttaatcat agcagtcata
     5761 ggctctgcag ttgctacaac ttatatacct atgtactttg agacaaagaa aagactcgga
     5821 gatgaaggtg ccttaaaatt tactaataat gttttaaata tatgctatat aatggctata
     5881 gtaatagcta ttattggtct tttatttaca gagcaatttg ttacagtatt tgcagcagga
     5941 tttagaaacg accctgctaa gttccaagca gcaatattat ttactaaaat aatgatttca
     6001 ggagttttat tcctgagtgg aagtaagata tttagttcgt ttttacaggt gaatgacagt
     6061 tttgtaattc ctgggcttat aggaatccca tataatatta taataatagc agcaatagca
     6121 ctaagtgcag gtaaaaatgt atggatactg ccagcaggag cattattggc tatggcgagt
     6181 cagctattgt ttcaactgcc atttgcgttt aagaagtcct acaagtataa gccatatata
     6241 aatttaaagg atgagtctat aaaagagtta gtcaacctag tattgcctat gttggtagga
     6301 gtagctgttg gacagttaaa tatatttgtt gaccgattat tggcaaccac tttgggtgat
     6361 ggaaagttgt ctgctcttaa ctatgcaaat aggctaaatg agtttgttat ggcattattt
     6421 gttacatcta taataacagt tatatatcct aaactagcaa aaatgtctgg taaagataat
     6481 aaagaaggat ttataagcac tattgtaaaa tcttcaaatt gtattatatt ggtggtgctt
     6541 cctatatcta taggagctat tatattagca gagcctcttg ttagaatatt attccaaagg
     6601 ggtaaatttg atgcgttatc aacagacctt acatctatag cgcttagatt atattcacta
     6661 ggtttattgg cttgtggagt aagagatgtc ttatataggg cattttactc tctttcagat
     6721 acaaaaacac caatgataaa tggaagtata gctttaataa taaatatagt tcttaattta
     6781 atattgataa gaccattggg tcatgcaggt attgctatat caactagtac atcaaacata
     6841 attacagtta tattattatt tatatctctt aaaaagaaaa atggatattt tggaggggat
     6901 aaaattataa agactggtct aaaaagtttg gtagcatctg gtgtgatggc agtagctact
     6961 ttattgatat ataataatct atatgcattt atgggttcag gaacaattaa agaaattata
     7021 tcagttggag ctggagtatt aggtggagct tctgtatata ctgtattgat agttttattt
     7081 aaggtagaag agatggattt agcttttgaa tttttaagaa aaggaaaaca aaaactactt
     7141 agaagataga taattacctt gaaattttaa attagagtca gaaaggatga aaatatggat
     7201 tataagaata attatgagat gtggttaaat tctccttatt ttgatgaaca aacgaaaaat
     7261 gagctattaa gtataaaaga tgatgaaaaa gaaatacaag atagatttta taaaaattta
     7321 gagtttggaa caggtggttt aagaggtata ataggagcgg gaactaatag aatcaatatt
     7381 tatactgtta gacgtgcgac actgggcgtt ttaaattata tcatgaaaac tcaaggagaa
     7441 gaaggtaagc aaaagggaat agttatagca catgatagta gatacatgtc tagggagttt
     7501 tgtatagaag tagcaaagac tttaagtgct tatggtgtaa aggcttatat ttttgaagaa
     7561 ttaaagccta caccagaact ttcttttgct gttagatatt taaagtgtgc tatgggaata
     7621 gtaataacag caagtcataa tcctaaagaa tacaatggat ataaagtata tgactcagat
     7681 ggtggtcaaa tctgtataga tatggcaaat gatataatag cagaagttaa taagattgat
     7741 gattacagta ctattaaaag tatagatttt gaagaagctt tatctaaaaa tttaataact
     7801 atattagata atgaagtaga tgatgagttt ataaaagctg ttaagaaaca agttttaaga
     7861 caaaatataa tagatgaata cgggaaaaaa ttaaaaataa tatatacacc tattcatggt
     7921 acaggaaata agccagtaag aaaagtctta aatgaatgtg gttttgaaaa tgtaatggta
     7981 gttaaggagc aagaattgcc agattctaat ttttcaacag taaagtatcc taatcctgaa
     8041 gaaaagtcag tgtttaatat agctattgaa atggcaaaga ataatggcac tgatttgata
     8101 ataggaacag accctgattg tgatagagta ggtatcgttg taaaagattc aagtggtgaa
     8161 tatgtagtct taaatggaaa tcaagtcggt tcacttttag ttagatatat attagagagt
     8221 ttagttgaag aaaataaact tcctaaaaac aatcctacaa taataaaaac tatagttaca
     8281 tcagaactag gtgcaaaaat agcaaaggct tataatgtag attgtttaaa tactttaaca
     8341 ggatttaaat ttataggaga aaaaataaaa gcgtttgaag aaagcaatga tagaagtttt
     8401 ataatgggat atgaggaaag ctatggttac ttaattggaa ctcatgctag agataaggat
     8461 ggtgttgtat cttcacttat gatatgtgaa atggcagcat actattcttc aaaaggtatg
     8521 aacttgtatg aagctttgat agatacatat aataaatttg gatactacaa agaggactta
     8581 aagtcagtaa ctttaaaagg catagatgga ataaaaaaaa taaaagagat gatgctttac
     8641 tttagaagtg ttaaaataga taatgtggct gatgtaaaag tagataaaat tttagactat
     8701 aaagatggtg ttgatgattt acctaagtca gatgtactta aatttttact tgaagatggc
     8761 tcttggatag ctataagacc ttcaggtaca gaacctaaaa ttaaatttta ctttggagca
     8821 aattcagaca atcaagaaga tgtagaattt aagttgaaca atttaatatc ttatatatta
     8881 aatgtagtgg attctatata aaaagctaag gggagataaa caatgaaagt atacaatgtc
     8941 ataatggctg gaggaggagg aactcgtttc tggccactta gtagacaaga agtacctaaa
     9001 cagcttataa atttaagtgg agaagatgct ttaataaacg aaactataaa cagaatagat
     9061 tctctagcaa aaaaagatga tttatttata gtaaccaatg agaagcaatt ggaagcttta
     9121 aaggatatag taaaagataa atgtttggat agtaatatat tgccagagcc atgtgccaga
     9181 aatacagcag cagctatagg ctttgcagca tttaacataa tgaaaaaata tggtgatggt
     9241 gttatgtgtg tatatccagc tgaccattat ataaaagatg aaaaagaatt taaatctatt
     9301 ttggaaaaag ctatctatat agcagaaaat aatgataaac tagtaactat tgggataact
     9361 cctacatttc catcaacagg atatggatac ataaatttta atagagaaaa tactatagaa
     9421 gatgttgcat atgaggtagt ggagtttgta gaaaaaccaa actatgaaat tgctaaagaa
     9481 tatgtaaact ctaaaaagta tgtatggaat agtggaatgt tcgtatggaa ggtatctaaa
     9541 atactagaag attttaagag atacttgcca aaagtatatg aaaaattaga agatataagt
     9601 aaatacttag gaacaaaaga agaaatggaa aaaataaaag aaatataccc aactatacaa
     9661 tcaatctcta tagattatgg tattatggaa agaagtaatg atgttatagt agttcctggt
     9721 gattttggat ggaatgatgt tggttcttgg gattctctag gtgcaatata tccaactgat
     9781 gatgaaggta atatcaaaag aggtgaaaat attactatag atactaaaaa ttcaattata
     9841 tattcagatg acaaattaat atcaacaata ggtattagtg atttgatagt agtatctaca
     9901 aatgatgcag ttatggtttg tagaaaagat aaagctcaag atgtcaaaaa aatagtagag
     9961 cagttaaaag aagaagatag acaagaatat atgtaggagg tgttcatttg attcctaaaa
    10021 aaatacatta tgtatggttt ggtggtccaa aaggaaatat agaaaatata tgtataaatt
    10081 cttggaaaga aaagcttcca gaatatgaga tagtagagtg gaatgaaaaa aactttgata
    10141 tagagaaaga aataaaagga aataagtttt tggaagaatg ttataaaaga aaactttggg
    10201 cattcatatc tgattataca agaataaaag tactctatga acaaggtgga gtttatatgg
    10261 atacagatat gcaaatatta aaggatataa ctcctctttt agaaaataat aggctagtct
    10321 gtgggtatga agatgataga gagtatataa atggtgctat aataggtgta gaaaaaggac
    10381 atcctttttt aaaagactta ttggagtatt atgaaaaaga agtacttact tcttcattgt
    10441 ttacaatacc aaagataatg actcatctta tggaaaagaa ttataagaag attgatccaa
    10501 ataattatga agaaggaata cgtgtttacg acaaagaata tttttatcct tttggattta
    10561 aagaagactt tacaccagaa tgtataacag aaaacacttt tgggatacat tggtggggaa
    10621 aaagttgggc taaaaagaga aattatttct tagaaagcaa acacttaaca ggtgtaaata
    10681 agatatggaa gtgttgtaaa atatttgcaa gtaatacttt acgaagctaa aagggagaaa
    10741 gtaaaatgaa gactttaaat gatgatagaa atattatgat tagaaaatat ctttatatat
    10801 ttgttttgtt tatcatatta cttagaaagt atatgatatc atttattgac ccaaatatgg
    10861 atatagggat gattaaatca gcgttatttt attcttcaat aggaatacta atgctacttt
    10921 ttttatttga taagagaaaa agtataacag aaatggtact agttggagtt tgtgtcttac
    10981 tttatttatt aaatagggaa ggagctatat tattaatcgt tttattagct gtatcagcta
    11041 agcaaataga tgataaattt atagttaaaa attatttaat aatatcggca tgttttttaa
    11101 tggtagctat attattattt aatttatttc cttcattaat atttaatcag gaagtccact
    11161 atagatatat agaaaaaata gatatgcttg ttacaagaat ggattttgga cttggtaatc
    11221 caaatagtgt attttatcat atggttacta tatatgcagc atatatattc ttaagatata
    11281 aagattataa taaatgggat agaatacttt tatttggttc tgcatttttt gtttatcaaa
    11341 ccacatatag tagaactgga tttttcacta tattagcagg attaatattt gtagaaataa
    11401 taagatggat agatataaaa aaaataaaag gactaccaat gctcctaaag acattaccgg
    11461 taatacttac tttatttagt gtaattattg gtacagtatt tgataaaagc actttattaa
    11521 atagattatt agcaagtaga cctaagttct ggaatgtata cttggctgaa aaggggaact
    11581 ttctaaaacc ttttggaaat tcatatagtc ctgctataaa agcaactaat ccattagata
    11641 gttcttatgt atatataatt agtgtactag gagtagttgc ttgtatatta tttatgtatt
    11701 tgatgtataa aggaatagaa agctttatag aaaaagataa aaaagcatat ttagtagctt
    11761 tatttatatt tttactatac tcttttgcag aaaatttatt attagaagct tcatttagtt
    11821 ttgcagtagt attactaata aaagaagtga tattaaatga taaaagggaa atagatttgt
    11881 ggaagatgaa aagtaggagg tagtaatgtt aatatcatta ataatgccaa cattaaatag
    11941 atatgatgat atatacttac ttatggacag cttagaaaat caaacttaca aaaactttga
    12001 acttatagta gtagaccaaa atgataatag caaagttaaa gaaatagttg ataaatacat
    12061 tgataagtta gatataaagt atataaaaag ctctaaaaaa ggattgagtt ataacagaaa
    12121 tgtaggcata gacaatgctg tagggcaaat tataggtttc cctgatgatg attgtgtcta
    12181 cgaaaatgat acattagaaa aagttataaa tttctttaat aaaaataaag attataaaat
    12241 atacagttgc aaaactatgg attcaaataa agttgatgca tttaagaaaa tgtatgatgg
    12301 aacttgtgat atcacaagtt ccaacgtttt ggatactata acatccataa ctttttttat
    12361 tgattttgaa ggtaaagact atacaagatt tgatgaaaaa ttgggtgttg gtggagagtt
    12421 tggtgctggt gaagagatag attatgtttt aaacttattg agtttaggtt ttaaaggaaa
    12481 atactttgga aatgatataa tttaccatcc tgcaaaaaaa cattctaaat ctaaagaaaa
    12541 gtatcaaaaa gattataact atggaagagg ctttggagcg ctttgcaaaa aggaaatagt
    12601 ctatagaaaa aattataagt ttgcaaaagt tatggtatca aaacttgtaa gaaatatagg
    12661 aggtcttata ttgagttcca atagagatta tcatagtgcc actataaaag gaagaattaa
    12721 tggatttaga cagtacaagt tataatgagg atggtgttta tggacaaggt taaattttta
    12781 ataaatatgc ttttggcttt ttttatatat ccatttaata agcataagtt taatggtaga
    12841 gatatctggc ttataggtgg acattcaggg gatatataca atgataattc aaagtttttt
    12901 tatgagtata tgctaaaaga acataatgat gtagaaactt attgggtagt aaataaagac
    12961 agtaaagtat ttgataaaat tccaggcaaa aaattaataa gaggaagtgt agaaaactat
    13021 ctgtattatt acaattcaaa agctatagta ttttcacatg caccatcagc agatatagca
    13081 ccatacaatt ttgctgtacc tgttcttaat tattttcata aaaaaacgat aaaagtgttt
    13141 ttaaatcatg ggactataag ttttaaaaaa agaaaaccta tgaacaaaaa gttcaaaaat
    13201 attatagata acctatataa aagctataat atagttacag caagttctga atttgaaaga
    13261 aatgttatgg taaatgattg gggaatgtta gatgactcag tttatataat tggaaatgca
    13321 agatatgaca atttaccaac aaatgaagtt gcacaaactc gagatatatt atatactcct
    13381 acatggagag attggataaa atttagttca ggaaaattta cggatacaga ttattttaaa
    13441 aatataatga attttttaaa tgatgacaaa ttaaataaaa tattagatga gaaagatata
    13501 aatgtaaaaa tttatatgca tcatcttatg catgagttta tagatgatat aaaagaaaat
    13561 ataacaggaa aacgaattgt gtttttagat aaaggggtaa ctctagcaaa tgaaatcaga
    13621 aaatcagctg caaatataac tgattattca agtgtagcca tagacttttt gtatatgaat
    13681 agacctatct tgttttacca attcgatttg gatgaatata tggaaaaagt tgattcatat
    13741 atagatttaa aaagtgaaat gtttgggtct ttggcttata ataatgatga agccgtgaat
    13801 aaacttattg atattattga aaataatttt gaggttatgg ataaccaaaa aaatgaaaga
    13861 aataagtttt tcagatataa tgataataag aactgcaaga ggatatatga ttgtgtatta
    13921 agtaaaatta aataaatatt ttataaatga tgaggaaggt aatatgaaga agaatttagt
    13981 atctataatt actcccatgt ataattctga aaaatttatt gaagcaacca taaaatcagt
    14041 attaaaccaa acttatcaag aatgggaaat gttaattatt gatgattgct caacagataa
    14101 tagtcctaat atagtcaaat cttatatgca acaggatagt agaataaaat gtataaagac
    14161 tgagactaat aagggtgtct ctaatgctag aaatttagca ctaagtaagg caacaggaca
    14221 atttatagct tttttagata gtgatgacca atggaatagt agtaagttag aaaaacaagt
    14281 aaattttatg ttagaaaatg actatgtaat ttcatttact tcatatgaac tgatggatga
    14341 aaatgataaa aaattaaaca aagtaataaa agttccacct aatgtagatt atagaagatt
    14401 attaaaagga aatatcttag gatgtcttac tgttgtgatt gataagtcta aattggattt
    14461 tgaaataaga atgagtggtg taagacatga agattatgtt ttatggttat cgatattgaa
    14521 aaaagggcat attgctcatg gaataaatga agttctagca ttatatagaa aatctagcaa
    14581 ttccctaagt ggtaataaaa taaaagctgc tatgtggact tggaatatat atagaaatat
    14641 agaaaaaata cctttataca aagctatata ctactttatt aattatggaa taaacggaat
    14701 caaaaaaagt tagacagaga ggaagattta attaatgtat aaatataaat ttactgtatt
    14761 tactccgacg tataacagag ctcatttact tgaaaatttg tacaatgatt taaaagctca
    14821 aacttatgat ttcaatgatt ttgaatggtt gattgttgat gatggaagta gcgacagtac
    14881 taaagagtta gttgaaaaat ttatatcaga aaataaatta aatataagat atatatacaa
    14941 agaaaatgga ggaaaacata ctgcaataaa tctaggtgta aaaaatgcag atggagagct
    15001 atttttcatt gtagatagtg atgatggttt aattaaagat tctcttgaaa ttgctaatga
    15061 tgagtgggat tctttagaga ataaagaagg atttagtgga gttgttggac tttgtgtata
    15121 tccaagtgga gatttgatag ggacagaaat gcctgaagat aagaaaatat gtcactttgc
    15181 agacctatat tttaagtatg gcgttaaggg agataaaagc atagtatttg taactgatga
    15241 gcttataaaa tttccttttc cagaaagaaa agaagtgaga tttttaccag aaagtgtagt
    15301 atggaatgaa atgtctaaat actataaagt tatatgtgta aataaaccta tgataataag
    15361 agattatttg gatgatggtt tgactaagaa tatattaagt aaaaatgcat taagaggtag
    15421 agcattagag tttttatatt taataaatca aaatacatat ccattaagta gatatccata
    15481 tatgtggata aaaaattaca taaatttagc cagatactca ttgttgtctg atagtcatta
    15541 ttttggtgaa ttaagaaaag tatctgataa attgttgtat ttagcattat tcccattagg
    15601 atattacaaa tatattggac aaagaaaatt agtatctaag taaacttgtt ggtatagtac
    15661 tgctagttgc tatataagga gagtaaaaat atgaatgagc ctttagtatc gataattact
    15721 cctgtttata attcagaaga gtttttatca gagacgataa agtcaatcca aaatcaaact
    15781 tataaaaatt ggcagctttt attagtggat gattgttcta aggacaattc aagtgaaatt
    15841 ataaaaagtt ttcgaaaaga agatgctaga ataaaatata taaagcttga aaaaaattct
    15901 ggagctgcag tatctagaaa tgttggtatt aagaatgcgg aaggtcgatt tattgcattt
    15961 gtagatagtg atgatttatg ggatagtaga aaattagaga ttcagataga atatatgtta
    16021 aaagaaaatg taggtttttc ttttacatct tatagatata tgagacaaga tgggtcaaaa
    16081 acgaataagg ttgcaagagc tcctaagaaa attgactatg aaggattact tagaaatact
    16141 ataataggat gttctacagt ggtcattgat aaggagattg taggagagtt cagcatgcct
    16201 ttggtaagaa gaggacaaga tactgcaacc tggttacagt tacttaaaaa ggaaaaatat
    16261 gcatatggga ttcaagaaga tttagtgaat tacagattag ttggaaattc tatatcaagt
    16321 aacaagataa aagcattaaa acgaacttgg aatacttata gaaatgttga aaatttaagt
    16381 ttaccaaaaa gtctatatgt attttgtttc tatgttttta atgccattaa aaaaagagta
    16441 taagttttat atacttggag gtaaaaaaat gaaaatagct atagctggga cgggatatgt
    16501 aggtttggtt acaggtgttt gtctagcaga ggtaggcaat gaaaatgtag tctgtgttga
    16561 tgtagatgaa caaaaagtta aatcaatgaa acttggaata gcacctatat atgaagaagg
    16621 cctagaagaa cttatggtta aaaattacaa cagaggaaga atagattaca ctacagacta
    16681 taaaaaagct tatgaagatg tagatgtaat attaatagct gtaggtacac ctgagagaag
    16741 tgatggttca gccaacctag attatataaa ggtagttgca aagcaaatag ctgaaactgt
    16801 gacaaaagat actctagtag taataaaatc tacagttcca attggtacaa atgaagagat
    16861 agaagattat ataaatagaa acctaaaaaa tgatgtaaaa gtagaacttg catctaatcc
    16921 agagttttta tcacaaggaa cagcagtaaa agatactcta catgcttcaa gaatcgttat
    16981 aggtgtagaa agtgaatggg ctagagaaat attagaggaa atctataagc cttttaatca
    17041 acctataata gttacaaata gaaatagtgc tgagatgata aaatacgcat caaataactt
    17101 cttagctctt aaaatatcat ttatgaatga tattgcaaat ctttgtgaaa tagcaggagc
    17161 taacatagaa gatgtagctt taggaatgag ttatgatgat agaataggaa gtaagttttt
    17221 aaaggcggga ataggatatg gtggttcttg ctttccaaaa gacacaaaag ctcttcactg
    17281 gttatctgaa cataatggtt atgaattaaa aacagtaaaa gctgcaatag aagttaatga
    17341 aagtcaaaaa cttaaattag ttagaaaggc atctaagtta gtagagagct ttcaagatat
    17401 gaaggttgct gttttaggtt tgacttttaa gccagacact gatgatataa gagaagcacc
    17461 atctatacca aatataaaat atttgctcga aagaggggca agagttactg tatacgaccc
    17521 aattggtgta aataatacta agaaaatatt tggtgactct atactttatg ctgattctgt
    17581 agatgatgcg atagaagatg cagagatatg ttttataatg acagaatgga aagatgtatt
    17641 aaattatgat atacataagt ataaggaaaa gatgaaaaat cctttagtcc ttgatggaag
    17701 aaattgttat aaaattaaag atatggaaga gttaggaatt gagtattatt cgataggaag
    17761 gtaaatatta tgaagactgt ttgttattta gctgatgggt caaatcctca tactttaaaa
    17821 tggtgtagtt tttttaaaaa taaaggatat gacattcatg taatctcttt aaatggaggt
    17881 cacatggaag gaataaaaat ttataatttt ggttctaatg tagaagaact aaaaaatgaa
    17941 aatatttcta aaaaaacggg atacttaggt tcaataaagc agataaagaa gctagtaaat
    18001 gaaataaagc cagatatatt gcatgcacag tatgcaagta gttatggatt tataggaagt
    18061 ctacttgggt atcatccata tattatttct gtttggggta ctgatattta tgatttccct
    18121 aataatggtt ttatacaaaa acaaattata aagcataact ttagaaaagc agactatatc
    18181 ttttcaaata gtagagatat ggctaaagag gctaataaat atacagctaa acatgtagat
    18241 gtaacctttt ttggagtaga tatggatagg tttaagccta tggaagtaga aaaagaagac
    18301 gcttttgtaa taggaattat aaagagttta gaaaaaaaat atggaataga atatttaata
    18361 caagcattta agatgcttaa agatgaatat aaagataaga aaataattct taaaataggt
    18421 ggctctggaa gtcagatgga caacctaata aatttagcta aagaattggg tatagaaaat
    18481 gatgttcagt ttttaggaag aatatctcca gaaaatgtaa gcaagacttt taattctttt
    18541 gatgtaactg tatttccttc tttaagagag ggatttggag tggcagctat agaatcagaa
    18601 gcatgtgaag tacctgttat agttacaaat gtaggaggac atccagaatc tgtatgggaa
    18661 aatgaaactg gcttaattgt agaaccaaaa caaccagaag aaataaaaaa tgctataata
    18721 aaactaatgg aaaatgatga acttagactt aatatgggta agaaagggcg tcaatttgtt
    18781 agagaaaatt atgaggttaa tttaaacttt aatgatatag aaaaaattta tgattctata
    18841 tttgataaat ataaaaaata aaatgaaaaa atacagcaaa agatagatgt tgttggctat
    18901 gcttaggtgc gtagcttttg ctgtttaaag gagggcttct agttatgcga gaaagtatag
    18961 atttagagaa agaaagcttt tttaataggc tttttaaaaa atataaattt agacatttaa
    19021 cactattaat tctagatatt tgtagcgtac tagtagcgtt tcgaatgtct ttaagcttga
    19081 caggtaattt aaatgcattt accactaatg atataataat ttcagtgtgt atatatatag
    19141 tacttcatat agtatcattt agattgttta agtgctacaa cacattatgg agatatgcag
    19201 gagaagaaga aattatatct atttttgtgg caactttagc ttatttaatt ccgatttata
    19261 taataaataa attattaggg tttgattatc ctataatgtt ttatgtatta aatacaatat
    19321 ttattataat gtttacaagt ggcgcaagaa tagcctatag agctataaga atagtcatga
    19381 acaagacata ttctagagga aaggtttcaa atatccttat aattggtgca ggagatgcag
    19441 gagaaatggt tatacaggaa ctaaaaagaa atccagaact taagaaagta gcagtggcta
    19501 taattgatga tgataaaaat aaaattggaa gaataatcca taatgtgaaa attgtaggaa
    19561 caacttcaga tataaaagat gtggtagaaa agcacaatgt agatgagata atcttttcaa
    19621 tagcaaacat agagaaacgt agaaaaaaag agattattga tgtatgtaaa aacactaact
    19681 gtaaaataaa gacaatacca ggaatttacg aaattataga tggaaaagtt gatataaaac
    19741 agattagaga agtagagata gaagacttgt tgggtagaga gcctataaaa acaaatttaa
    19801 gagagataag taattacatt gagggaaaag taatcctaat aactggagga ggaggctcaa
    19861 ttggttcaga gctttgtaga cagattgcag gatttaatcc taaagagctt attatagttg
    19921 ataattatga aaataatgct tactcaatac aacaagaatt acttagaaaa tataaaaata
    19981 aattagattt aaagacagta atagcatcaa taagagaaga aaaaagaatg gatgaaatat
    20041 ttaataaata taaaccagaa gtggtatttc atgcagcagc acataaacat gttcctctta
    20101 tggaatcgag ccctggcgaa gctataaaga ataatatatt tggaacttta aacatagctg
    20161 gcttgtcttc aaaatataga gctaagaaat ttgtccttat atctacagat aaggctgtaa
    20221 accctactaa cataatggga gctactaaaa gagctgctga aatgattata cagactatga
    20281 atgctgaaag ccagactgaa tttgttgctg ttagatttgg aaatgtgctt ggtagtaatg
    20341 gtagtgtaat tccacttttt aagaagcaaa ttgaagatgg cggaccagtg acagttactc
    20401 atccagatat tattagatat tttatgacaa taccagaagc agtaggctta gtcatacaag
    20461 ctggggctat ggctaaaggt ggagaaatat ttgtacttga tatgggagaa cctgtaagaa
    20521 tattggattt agcaaaaaac ttaattaaat tcagtggatt tgagccagat gttgatataa
    20581 aaattgaatt ttctggtctt agaccaggag aaaagttata tgaagaacta cttatgtcag
    20641 aagaaggtct gttggataca gagcataaaa agatttttat tggtagacca atagatgttg
    20701 atagagaaaa aataacaaaa tacttaaaac ttttaagaga aattactaac aatgaagagg
    20761 ttgaaaaaat agatggtatt atgagggaat tagtgccaac ttatattaaa ccagaagatg
    20821 ctaatatcaa agaaattgca acaactagag aaaagtagaa tatatttcta atttgtaacc
    20881 agggggagca aaaagaaaca aatatatact aaaaagaaac aaaagattac aaaaagatta
    20941 caaaaagatt acaaaaaagg ttgcaattta ttttgatgta agatagaatg ttaattagga
    21001 attggaaacg aaggaacaaa atgttaaatt ttcgaaagga ttaggtattt gagattatga
    21061 tgaatattaa aaataaaaaa catatattga aaaaatttat agctatggtg ttaatagcag
    21121 gagttgtcac agtagaagca ggagcaataa cggctagtgc agcagagcca actaattcac
    21181 ctatgagtgc aacagtagac cagtgtgatt ttttaaatgt aagaagtgga gctagtgcaa
    21241 atgatgcagt agtaggaaag ataaacacag gagacaaagt tgaagtttta gaattacatt
    21301 caaatggatg gattaaaata aaaagtgttg acaatgttac aggatgggta aatggagatt
    21361 atttaactat tcaaggtgga aatgtagatg caaaggtaca aaatgtttta aacttagcat
    21421 ttaagcaaca aggtaagcca tatagatggg gagcaactgg accaaatgct tttgattgtt
    21481 ctgggttcac ttcttatgtc tataaaaatg gagcaggagt taatttacca agagtatcaa
    21541 gatcacaagc aacagtagga aagaaagtat caagagcaga attaaaacca ggagatttag
    21601 ttttctttgg ttcaggtggt tcaataaatc acgttggatt gtatgtagga gattctaaat
    21661 tcatacattc accacaaaca ggagatgtag taaaagttac tagcatggct ccaggaacta
    21721 attatgcaag aagacttata actgctacac gtgttttaca ataataatag atattgattt
    21781 acataggatt gaatattaac attaaatata taattacatt taatgtttta catagagatt
    21841 taagagttta gtaatattaa aatagtgatg aacgttataa aaacagcaaa gaagataaat
    21901 ttctttgctg ttttttttat aataaattat ttcatattat aatcaaatat caaatataaa
    21961 ttttaactat attattcaat atttgacaga taatatgaat tttagatata cttaataaga
    22021 agtatattgt agaaaaaata aatttaaaaa attaaggggg atgaaatgaa aaaaataagt
    22081 atattagtat tatcattgat aatgacactt actatgtgta gtgtaagttc atttgctgat
    22141 tcatcaaatg ataaagaaat gagagctgct tggatatcta cagtttataa tttagactgg
    22201 cctaagacta agaataatga agccaagcaa aaaaaggaat acacagattt attggacaaa
    22261 ttaaaaagtg taggaataaa tacagcagtg gttcaagtaa gaccaaaatc agatgcttta
    22321 tataaatcaa atataaaccc atggtctgaa tatcttaccg gtacacaagg taaagaccct
    22381 ggatatgacc cattaccatt tttaatagaa gaagcacata aaagaggaat ggaatttcat
    22441 gcatggttta atccatatag aataactatg gcagatgaga gcatagataa attgccagca
    22501 aaccatccag caaagaaaaa tccaagctgg gtagttaaac atggaaataa gtattactac
    22561 gacccaggtt taccagaagt tagaaagtac atagtggata gtatagcaga agtagttcaa
    22621 aattacgata tagatggagt tcattttgat gattacttct atccaggagt aagtttcaat
    22681 gatactgcaa cataccaaaa atatggaaaa ggacaaaata aggatgattg gagaagagaa
    22741 aatgtaaata ctctacttag agatgtaaaa gcgtctataa agagtataaa gcctaatgtt
    22801 gtatttggtg taagcccagc aggtatatgg agaaataaga gtagtgaccc aacaggttca
    22861 gatacatcag gtaatgaaag ttatgtaggt acatatgcag atacaagagc atggataaaa
    22921 caaggattga ttgactatgt agttccacaa ctttactggc caattggtct taaagcagca
    22981 gattattcta aattagtggc atggtgggct aatgaagtaa aaggaacaaa tgtagactta
    23041 tacataggac aaggtatata taagcaaggt caatcgagtt atggtggaca aaatatagca
    23101 aaagaaatag tacaacaagt aacattaaat agaaagtata gtgaaataaa aggtagtatg
    23161 tatttctcag ctaaagatat agcaaatagt acttctatac aaaaggattt aaagagttta
    23221 tattctagta gtgaagaacc agttactcca ccatctaatg ttaaagtgga gaaattaaga
    23281 ggcgacgaaa gatatgacac agcagtagca ataagtaaaa aaggttgggc tacaaattca
    23341 gatacagtag tattagtaaa tgggtactct atagttgatg gtataacatc aacaccactt
    23401 gctacatcaa atgatgctcc tatactattg gtaaataagg ataatatacc tacatccact
    23461 aagaatgagt taaaaagact taatccaagt aaagttattt taattggagg aaataactct
    23521 attggagata aagttgagag tgagataaaa gatacattgt caaatgtatc aataaataga
    23581 gttggtggtt cagatagata tagtacatct ttaatgatag caaaagaatt agtaaaaact
    23641 aatccagtag aaaaactata tataacaagt ggtacaggtg aagcagattc tctttctata
    23701 gcttcaaaag caggagaaga aaagcaacca atagtattag tatcaaaaga taatgtaagt
    23761 gatgaagttt acaattggat atcagattta aaagtaaaag atgcttattt tataggtggt
    23821 aatctaagta tatctgattc agtaataaat aagctggata aggtcattac aaatgatgta
    23881 tctaaaaata gaatagctgg agaaaataga gaagaaacaa atggaaaagt aatacaaaaa
    23941 ttctatccaa atgctgaata ttcatcaatg tttgtaagta aaagtaatca attggtagat
    24001 gcattaacat caggtccttt agcggctaaa ttaaaatcac cagtagttat gcttggaaat
    24061 agtgtaacat ctgctcagaa aactgcttta gagcctaaga aaactactct agtatacgaa
    24121 gctggagatg gtataaatca aaacacatta aacactttct taaacttagt taagtaataa
    24181 aaaagttaat ttaaaataca gagtatttta caaatgtaga ttaaaatgaa aattatcatg
    24241 ataaattaga aaataaaaaa gaactatatg cattttgtaa tcaagtgtac acagcaactt
    24301 gaaaataatt atgcgatata gttctttttt agtaattaat cttatacttt ttaataaact
    24361 ttatgttgaa ttttttattg tttaaactct atgtcattaa atataaaatc gtgtaatatg
    24421 tctaaagtat ctgggtcaaa tctaagaacc catccagctt ttccatatat accacctgta
    24481 ctatgaattt catcatcaat aggaaattca aattgcttaa tatttaagtc acccattttt
    24541 aaaacttgag ctcctaaaga aagtattgca ttaggcttca tgttagtttt aacatatgga
    24601 agaactgcat ctaataaacc tggatattta gtaacaggta aagtttccgt tttcttgatt
    24661 atagcttgta taatctgtct ctgtctgcca tctctagcaa aggctgtatc gttgtgtctg
    24721 atacgtgcaa aagatagtgc ctgatatcca tttagagtct gctttccaga gtttctaatg
    24781 tattgtatgc tacctttatc atcactttta ctccatttat aagtttcagg aataaattta
    24841 tttagttctc gtatttctcc tttttcaaca gtaacctcaa cgccaccaat agcatcaatt
    24901 atatacataa atgattcgaa attaacacaa gcataatttt gaatatcaat attaaaattc
    24961 tcttcaattg tttgtattaa taaatcagct tgtccataag cataagcatg agtaagtttt
    25021 tgtttaccat gaccagggat gtctacatag ctatcacgag ctaatgatgt aagtttgata
    25081 tcattgtgtt tgttatcaat agtaagtatc atcatagcat ctgaccttga agaatcttca
    25141 tttggtctag catctgttcc cataagtagt atgttaatta tcccatcttc atttttatgg
    25201 tcattgttat ccaataaatc actacttatg ctcgagtcat gaatagcaga taatttataa
    25261 taaaaatatc catagacact tatagggaat attactacca agaaagccag tagtataaca
    25321 aatttcttta attttgacaa aagtacccct tctttcttct ttttcctgta tattttttaa
    25381 tagcatacac ttaattatat taaagtattg agatatattc aatacttgtt tcagttacaa
    25441 aaaaaagaca atgatataat ttataagaaa atttatcgac ctatatatat agttaaaagt
    25501 atatataata tattttttaa aagtaattta tattttaaaa taaaaacaca ccccataaat
    25561 acaaagtaat ttgcatttaa gaggtatgta tttatcatca aattattggt ttgttttgga
    25621 atttctaatc ttcaaccata atatctttaa atatgaaatc atgcattgca tctagttcat
    25681 attcctcaaa aggtattaca tagcctgcat tacctatttt tctaccattt tcagtagaaa
    25741 gaggaaactc catagatttc aaatttaaat ttcctatact taaaagttct tttcctaaag
    25801 atattatttc attaggattc atattagttt ttacatacgg aagtattgtg ttaactagat
    25861 taggatattt agtgactggt aaatccttaa caccatttat taaactctgt ataacacttc
    25921 tttgtcttct atctctttca tctgtactat cattttttct tatacgagaa aatgcaagtg
    25981 tctgatatcc atttaatttt tgctcaccag aatttcttat atatttaaga gaacctttat
    26041 tgtcattttt attccattta taagtttcag gaataaattt atttaattct cttatttcac
    26101 tcttatcaac agtaacagta actccaccta aagcatcaac tatatccata aaagagaaaa
    26161 agtcaactac ggcgtagttt tgtatatcaa gttggaagtt ttcttctata gtttctatta
    26221 ataagttagc ttgtccatat acgtaggcat gtgttaattt ttgttctcca tgtcctggta
    26281 tattaacata agtatctcta tttaatgaag ttagcttaag acttttattt ttattatcaa
    26341 tagtaagtat catcatggca tcagaacgag aaacttcttc tcctggtctt gcatctgtac
    26401 ctaacaataa tatgtttgtg atattttctt cgtttttata gtcattacta ctaagcgcct
    26461 ctgtatttat actatcatct tgtatagttt ttaatttagt aaaaacatat ccatatatac
    26521 taacaggaaa tgctataact aaaagggcta gaaatataac gaactttttg agtcctgaca
    26581 ataatatccc ctactttcta aattttttaa ttacacatag ttaattatat taaaaatttg
    26641 ttacataagc aataaaaaac acaataaatt agcataagtt tgtcataata taattatttt
    26701 tatagcattt tatagaagaa agtgtgtagt tattattgat tttattggaa tataattgta
    26761 tgaagactta aatttttata aactaatgtg tatattgaaa aaaatatttt cctgaatgta
    26821 gttatagcat cttatgaaag gtgcaaattg taatttaaaa tttttagtgt ataataagaa
    26881 ttgaaaattc aaaccgataa aaattaataa aaaataatta taaattaata atttggggga
    26941 ggaaatgtat gataaaatta atagcaacag atttagatgg aactttgtta gatgaaaaga
    27001 gcgaaataaa tccagagttt tataaagtat ttaaaaaatt aagagagaga gggataatgt
    27061 tttctgctgc tagtggcagg cagtatcaaa atctgataaa aaaatttgaa gatataaaag
    27121 atgatatgat gtttatatca gaaaatggaa cactagtagt atataaagga aaagaaatat
    27181 tatcaaatcc tttaaataaa gaattagtaa atgaaatcat agagacaaca agaagtataa
    27241 aagggaaaaa aattgtaatg agtgggaaaa aatacgctta tatagaaagc aaagatgaag
    27301 cgtttataca agaggttagt acttattatg caaagtttaa aattgtagaa gatttgacga
    27361 aagtagaggg agacatattg aagatagctg tgtttgactt caaaggtgca gaacataata
    27421 ataatatcta ctttgaaaag ttttctgata gagctcaagt atgtatttct ggagtggagt
    27481 ggcttgattt aactgcaaaa ggtgcaaata aagggagtgc cataaaaaaa gtacaaaaaa
    27541 tgttagatat aaaatatgaa gaaactatgg tatttggtga ccagttaaat gatgtggaaa
    27601 tgatgaaaag tgcctatcat agttatgcca tggaaaatgc aaatgaacat ttgaaacaaa
    27661 ttgctagatt tagagcaaaa agaaatactg aaaatggcgt tgtagataag ataaaagagg
    27721 ttataaaaat tggatagtca tatgtataga tgaaaaagat tattttgaag aaatcaaaaa
    27781 aatatcaatg taattttgat aaataagttt atttatgcga aaattacatt gatatttaat
    27841 aaacatcaat aatagatatt tattttttta tgatattcag tattttgttt tctatttgag
    27901 ttgcattttc agcagaaatt aaataaacat acctacctgc cttctcaatt atagtattat
    27961 ttgctatttc agaattgatt ttttctccat gtccttctcc aaaaggtgct tgtatcatat
    28021 cttttttata attttctaga gttttataga ttttatctac ctcgtcagtt tttataacga
    28081 taatatcttc tagagataat ttttcagaag aattaattac aaaaccttga attatgtctt
    28141 cctctacatc attaaaatag ttaaaatcct ttgcatcaaa gatttttgat tcctttataa
    28201 gtaaatcaga agattttaat gcttttttta tttttgatgt agaaacgttt ttgtaatcac
    28261 cacttgaaga acaactaacc attcctaatg ataagattat cgaaaaaaac aatattaaaa
    28321 tttttttcat gataaacctc caagtttttt aaactctgtc ttaaattagt ttactacata
    28381 attatataaa aataaatgta tttaatgtta cagttttgat taataatgta atattttgat
    28441 aataatacct attgagaggt gattagaaat gagaatacca aaacatgtag gaattatacc
    28501 ggatggaaat agaaggtggg caagtcaaaa tggtatgaca aaagataaag gatatgaaag
    28561 tggaatagac cctggactag agtcttatag attatgtaga gatttaggct gtgaagaggt
    28621 gactttttat ggatttacaa ctgataatac aagacgtcca tcagtgcaga caaaagcttt
    28681 tacaaaagca tgtattgatg ctgcaaatat attaatagat gaaggtgctg ctttattagt
    28741 tgtaggaaat acaaaatcgc caatgtttcc agaagaatta ttaccatata ctaatagaat
    28801 taaagccaaa gaaggtcaaa taaaagcaaa tcttctggta aattatggtt ggtattggga
    28861 cttaaataat atatcaggag tagaaaatgt aaataaaaat aatatacagg attacataca
    28921 gtcatttgat gtatccagac tagacttgat aatcagatgg ggtggaagaa ggagattaag
    28981 tggtttcctt cctgtacaat caatttatgc agatttttat gttatagata attattggcc
    29041 agattttaag agtgacgata taaaggacgc atttagttgg tatgatacac aagatgtcac
    29101 tttaggtgga taattaaaaa tattctgatt taaggttgta gagtgtttta aattattgaa
    29161 aaaaaaactt cttgatggta aaataacact aataatatgt aaaagtgtaa aaatttatac
    29221 caagaagggt gaagaaatgt caaaaggcaa taataacaat aattcaagaa acaaatctaa
    29281 aaagaccagt catctgaata gaaaaaagcg aaaattaaat aagaaaaagt tagcagtgtt
    29341 gatttgcttt acagttttat ttttatttat tgcatttaag gctactcaag gtgtagtagc
    29401 tttggtaaaa agtatggata aaagtaataa aactagtcaa caacaaaatg ttaactcaga
    29461 acaatttgac cttggtaatg aagaggaaaa taaaaagaaa aaatatactg tatttataga
    29521 cccaggtcat ggaggcaatg ataaaggaac tgaaagcaag accagtaata gatatgaaaa
    29581 agacctaaat ctacaaattg caaaaaaatt agcaaataaa ttatctaaac aaaaggatat
    29641 tcaagtagta gtatccagaa ctgatgatac atatatatca ttaaaggata gagctatctt
    29701 agcaaataat agttctgctg atgtgcttgt ttctattcat ttaaatgcag agaaaaatgg
    29761 taatacagca acaggtatag aaacttggta taggaataaa gctacagatg gttcaaaaga
    29821 acttgcacag acagtacaaa gtactatagt atcctatgtt aaagttagag ataggggaat
    29881 agttgaaaat aactttgaag tacttagaga atcaaatatg cctgctatat taatagagtg
    29941 tggtttttta acaacacctt cagaggaaca aaaaataata aatgaaaaat atcaagacca
    30001 acttgcggaa ggaattgttc aaggtgtact ttcataccta gattctaaag ggaataagta
    30061 aattaacttt actttaatgt gaggataaat ttaaaagttt aactgtgtaa attgtattaa
    30121 ctttatttcg taatgttgga aatattgttt gaatttagaa actatgaaat tagaaattat
    30181 tttatctata tctaatttca tagttttttt tgcaaaaaat ttatagttat aaaattttaa
    30241 aaaataaatt tagtataatg taatgtagtt atttatatgt gattttaact tgcattgatt
    30301 tgctatcaat tgtgctttat aattagtata tataaagttt aactgtaaga taatttaaaa
    30361 aataggggaa tttatatgaa taaaaatagc atgacaagaa tttacagttt aaataaaata
    30421 atttttatta taattggaat tttaggaata gttttactca caagacatat tgaggtagat
    30481 attaaagttt taattttaat tttattaacc ttgtttagta taaatgtatt tatttcatat
    30541 cttaaaatta agttgtatga ggataaaatt aatttag
//
LOCUS       DAEPHU010000052        30407 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 01A10CD0081
            SAMN05941466-rid12468953.denovo.052, whole genome shotgun sequence.
ACCESSION   DAEPHU010000052 DAEPHU010000000
VERSION     DAEPHU010000052.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941466
            Sequence Read Archive: SRR6291087
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 30407)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 30407)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068158.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 22:43:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,892
            CDSs (total)                      :: 3,805
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 87
            rRNAs                             :: 8, 1, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 55
            CDSs (without protein)            :: 55
            Pseudo Genes (ambiguous residues) :: 0 of 55
            Pseudo Genes (frameshifted)       :: 21 of 55
            Pseudo Genes (incomplete)         :: 28 of 55
            Pseudo Genes (internal stop)      :: 16 of 55
            Pseudo Genes (multiple problems)  :: 8 of 55
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..30407
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941466-rid12468953.denovo.052"
                     /strain="01A10CD0081"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            complement(<1..813)
                     /locus_tag="KR231_002409"
     CDS             complement(<1..813)
                     /locus_tag="KR231_002409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pilus assembly protein PilM"
                     /protein_id="HBH0004776.1"
                     /translation="MAIIKKILNLEINDDYIRLVFLRKSHKKVFIDKSIIKEINFDIK
                     NDSNSIEKIKYIEDVVRFVKEEIGKSKILYKNLYFNIQIQDIVIRNVEVLNTKKKRDI
                     LSMIEFEITQYIPININNYSIKYKVINSKNDKLNIQVILFPKSIIQLIKNISENLNMN
                     PKTININFDILQKLINLNLIENFSEEGVFIECKKSQLIINITKDKKIRETYLLSKEGK
                     SYEFIKRLLRDFKYVYYYGIENCFIEEYFKYTDKSIEVNPLRLKDKVKVENNF"
     gene            complement(866..1225)
                     /locus_tag="KR231_002410"
     CDS             complement(866..1225)
                     /locus_tag="KR231_002410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system protein"
                     /protein_id="HBH0004777.1"
                     /translation="MINLINKKRKGFTLVEMIVVVTILGVISSIALVKYSKVQESAKL
                     NADYTNAANIVTAASMAINDDEKTIDSLSVETLKEKGYLNTVPVPQSTSGKFELVIND
                     SGTDISVNINSKQFYPK"
     gene            complement(1279..2364)
                     /locus_tag="KR231_002411"
     CDS             complement(1279..2364)
                     /locus_tag="KR231_002411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system F family protein"
                     /protein_id="HBH0004778.1"
                     /translation="MRLSKNIFYNLEKFYLVLNRISDKEIRVICKEIGILLESGCEIT
                     KIFEIIESQSSKKAKNLLSIVSNHIQKGNSIAESFQITGIFSKFFISMIKAGETSGNL
                     DIIMSDLSNYYDKEYKLKMKIITISIYPIILIILSILSMLFIFVFVIPNFQVVFTNNG
                     IEPPLITRVLMGISTVVTNNLAYIIFSFILFSIGSIYFFITNDNIKKLINSLKFKIPF
                     IKKINQLVATTRFSRALSVLISSGIQIVEAIDMSASVIDNEFIYERLKISNNYIKKGN
                     SIGKSLNLANVFPKLFISMANTGEESGKLDKSLNVINKFYENELNNKIEQIMKFIEPM
                     LIVFMGLIIGTFILAMVVPMFDAITNF"
     gene            complement(2535..3914)
                     /locus_tag="KR231_002412"
     CDS             complement(2535..3914)
                     /locus_tag="KR231_002412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II/IV secretion system protein"
                     /protein_id="HBH0004779.1"
                     /translation="MIKIILEESSLPMLIPEKLAKKYNVFPVEFQDDNLVVEIEDEDI
                     YALQDLRLATGKEIILKKEKKELISEKIEKYYNSFELDEDYAKKLFENLLEKAIKENA
                     SDIHIEPFKEHLIVRMRVDGELKEVSKFLVDVYPSLSTVIKLKASMDITEKRLPQDGR
                     VDIKLGGNLIDIRVSSIPTVYGEKIVLRILNRDTFLKDKLELGFSEEAIKSINRIINK
                     RAGILLVTGPTGSGKTTTVYSLLNDLKGINKNIMTIENPVEYKMDGISQIQVNSKVGL
                     SFDVGLRAILRQDPDIIMVGEIRDAETAKIAVRAAITGHLVISTLHTNDAVSSIARLL
                     EMQIPPYLLNASLIGVISQKLVRKVCNHCSHEIMIKDNFSGDVNTKVAVGCEKCNDKG
                     YFGRTAIYEILEINDDIKTCIRNMEDSSTIKDVAQNNGMITFEDSCKRLINEKITTLE
                     ECLVVNEMI"
     gene            complement(3907..4587)
                     /locus_tag="KR231_002413"
     CDS             complement(3907..4587)
                     /locus_tag="KR231_002413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417129.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF881 domain-containing protein"
                     /protein_id="HBH0004780.1"
                     /translation="MKKQYVFIILASTILGILVGTIFRDYSNEETVYTSKDKSIRKEI
                     KMTRKSIKELTKEKDKLDKEINSMKQNQKNSEEISEIETLRDSLSYSDVKGSGIILSI
                     DAIDEKTGNIANSIDYNKILVKVINELKVNGGKYIEINGQRINQYSEVVLAGSHININ
                     GVPVAQPYEIKCIGDKEKLSNYVDKGSKYLDSIQTNYPMKISIKTEENISMKKMNIPN
                     KLKYIKGD"
     gene            complement(4979..6058)
                     /locus_tag="KR231_002414"
     CDS             complement(4979..6058)
                     /locus_tag="KR231_002414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HBH0004781.1"
                     /translation="MEGKVKKAFPGGNTSQGSYSFFDYIIPENVKRVFCLKGGPGVGK
                     SSLMKKIYKEFLHRGYDIDLYHCPSDPSSLDGLVIKKLGVVLMDATAPHTMDPKLPGA
                     LDEIINLGDYWNTEELEKNKQEISVYDKDISNSFKRAFKFLKSAEPIFRDIEEKYSDC
                     MDYGKVNLVTEEFIKRLFDGVKSTGNLKREKHLFGSAITPVGCLDYTENILKDVKKVY
                     YLDGEIGTGKTTLLNKVYKKAIEKGLNVEVYHYPLIPEKIETVLLTDLDIGITISTTF
                     KEEDTIDLNQFLNREKLLKYEEDIKFDEKVLDDLICWAVLNLKRAKSKHDIIESYYSP
                     NMRFDEVGKLRDKLIKRILKYEENL"
     regulatory      6346..6461
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00050"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="FMN riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="flavin mononucleotide"
                     /db_xref="RFAM:RF00050"
     gene            6636..8006
                     /locus_tag="KR231_002415"
     CDS             6636..8006
                     /locus_tag="KR231_002415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBH0004782.1"
                     /translation="MKQKWIVLIIICIGVFMSTLDGSILNIANPTIAADFKINMSQIQ
                     WVVTAYMLVVTATMLFFGKLGDKVGSNRLYTLGFFIFTIGSFLCSMSNNLSTLISSRI
                     FQAVGASILMATGLGIVSNAFPANEKGKAIGITGAVVGIGNMSGPVIGGIILEHFGWP
                     SIFIINIPIGIIAVFLGIKFLPKPVLDEQNKSFDIPGLLLFASCTTLILLAMNEKGNT
                     RLYLGITALIIFLLLALREVKFEQSFIDLPLFKNRNFTVGNIIGVACYFPQMAVSFLL
                     PFYLEQLKNLSPMMAGYVMTVHPLIMVLIAPIAGSLSDKHGAKNILTASFSFMTISLV
                     GMALLKADSPLYLLIVCLVIFGLGLGAFSSPNNSSILADVPPQKQGYGGSFLATIRNL
                     SFALGTAFFSSFFAQSLTYNQKFKSHTSAYVIASNQSYWIAASVCFVGLILTVFFMRK
                     TDKSIS"
     gene            complement(8272..8883)
                     /locus_tag="KR231_002416"
     CDS             complement(8272..8883)
                     /locus_tag="KR231_002416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YihA family ribosome biogenesis GTP-binding
                     protein"
                     /protein_id="HBH0004783.1"
                     /translation="MKIRSSEITMSAVNKSQYPAEGIPEIALAGRSNVGKSSIINTLL
                     NRRNFARTSQTPGKTRTINFYLINNEFYFVDLPGYGYAKIAKSEKEKWGGIMERYLES
                     RQELCSIFLLVDIRHEPTADDKLMYEWIKHFGYNCVVIATKADKISRGQYQKHISIIR
                     KKLQMESSEKVIPVSSLKKTGVEELWEEIVNQYNQHGYEITVD"
     gene            complement(8873..11236)
                     /gene="lon"
                     /locus_tag="KR231_002417"
     CDS             complement(8873..11236)
                     /gene="lon"
                     /locus_tag="KR231_002417"
                     /EC_number="3.4.21.53"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endopeptidase La"
                     /protein_id="HBH0004784.1"
                     /translation="MEQNYTKIDHELPLIPLRGLAIFPYMILNFDIGREISLKALDQA
                     MMDEELIFLTSQKEAEVDEPGEEDFYHVGTICKVKQMIKLPGDTVRVLVEGVSRGRVK
                     KIEQEDGYFRAVIEEIVFDSDNLDSETEVEIEAFVRNVFDAFEEYINIGNRVSPEILI
                     SLADIEDVDRFIDTIAANIYLKSSQKQEILEEFDIRKRLELIYSILLEEIDILKIEKK
                     ITLRVKKQMNKVQKEYYLREQLKAIQKELGEEEDINSEADEYREKLKKIKAPKTTKEK
                     IEKEIDKFSKISSMSPDVSVSRNYLDTIFSLPWNKETKDKLDITKAKDILDEDHYGLE
                     KVKERILEYLAIRTLAKSLKGPIICLVGPPGTGKTSIVKSIARALNRKFVRISLGGVR
                     DEAEIRGHRRTYVGSIPGRIINGVKEAQTKNPVFLFDEIDKMAADYKGDPASAMLEVL
                     DPEQNKDFVDHYLEIPFDLSKILFVTTANSLSNIPRPLLDRMEVIEVSGYIEEEKLNI
                     AKKYLLPKQIKEHALKENFIKIDDETLRSIINHYTREAGVRTLERTIGKICRKVAKKY
                     VEDPTLEEVVINKSDLETYLGKDMFKYQLAEVNPQIGLVNGLAWTEVGGVTLEVEVNV
                     LKGKGEIVLTGKLGDVMKESAKTGISYIRSIVDKFDIDPEFYKTNDIHIHIPEGAVPK
                     DGPSAGITMALAVISALTKRPVPGNIAMTGEITLRGRVLAVGGVKEKLLAAHRAGITK
                     VLIPKECEADLDEIPENVKEKMEFVLVEHMDEVLEQALLKSGENNEN"
     gene            11416..11928
                     /locus_tag="KR231_002418"
     CDS             11416..11928
                     /locus_tag="KR231_002418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromate transporter"
                     /protein_id="HBH0004785.1"
                     /translation="MLKLFLTFLKIGAFTFGGGYAMVPLIQDELVNKQKLLEQEEFID
                     YLSIAQSYPGVLAVNISVLLGYKLYGIPGVLICTLGSALPSFCIVLVLSYLYFKNSSS
                     KILDGFFKGVAPVVIALILYSFTSMFKKLPKSKTNILLLIIAVLSVGVFNISPIYLII
                     GGGVYSLCQK"
     gene            11916..12443
                     /locus_tag="KR231_002419"
     CDS             11916..12443
                     /locus_tag="KR231_002419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromate transporter"
                     /protein_id="HBH0004786.1"
                     /translation="MSEIILLFLIFLKIGAFSFGGGYAMLPFIQQEFISKYHFITNQE
                     FLDLLAISQSTPGPVAINSATFVGFKTAGFFGSLAATIGVTIFALIGLTIISKLFSKF
                     KNNKKVENLLTVLRPITLGFILSAAFSSAKEVNWDLYGIIAFIASFYLLYKGKIGSIA
                     IVFVFGILGILLTFL"
     gene            complement(12514..13764)
                     /gene="clpX"
                     /locus_tag="KR231_002420"
     CDS             complement(12514..13764)
                     /gene="clpX"
                     /locus_tag="KR231_002420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit
                     ClpX"
                     /protein_id="HBH0004787.1"
                     /translation="MSKYEEKRQLKCSFCGKNQDQVRRLIAGPNVYICDECVELCDEI
                     IQEEIEDTIDEDTTSLPKPKEMMEILNDYVIGQEKAKKALSVAVYNHYKRIYSKKSSS
                     KDIEIQKSNILLLGPTGSGKTLLAQTLARTLNVPFAMADATSLTEAGYVGEDVENILL
                     KLIQAADFDIEKAERGIIYIDEIDKIARKSENPSITRDVSGEGVQQALLKILEGTVAN
                     VPPQGGRKHPHQEFLKIDTTNVLFILGGAFDGLEKIIQKRGGDKTLGFGAKIESKKEL
                     DLGKLYEKVLPEDLLKYGIIPEFIGRIPVLATLELLDEDALMQILQEPKNALVKQYKK
                     LLELDDVELEFEEGALRAIAKKAIERNTGARGLRSIVESVMMETMFEVPSRDNIKKVI
                     VTEKSVNEDSVNPIIVLKDQEESA"
     gene            complement(13783..14367)
                     /gene="clpP"
                     /locus_tag="KR231_002421"
     CDS             complement(13783..14367)
                     /gene="clpP"
                     /locus_tag="KR231_002421"
                     /EC_number="3.4.21.92"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp endopeptidase proteolytic
                     subunit ClpP"
                     /protein_id="HBH0004788.1"
                     /translation="MALVPVVVEQTGRGERSYDIFSRLLKDRIIFLGDQVNDATAGLI
                     VAQLLFLEAEDPDKDIHLYINSPGGSITSGMAIYDTMQYIKPDVSTICIGMAASMGAF
                     LLAAGAKGKRLALPNSEIMIHQPLGGAQGQATDIEIHAKRILKIKETLNEILSERTGQ
                     PLEKIKMDTERDNFMSALEAKEYGLIDEVFTKRP"
     gene            complement(14517..15803)
                     /locus_tag="KR231_002422"
     CDS             complement(14517..15803)
                     /locus_tag="KR231_002422"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trigger factor"
                     /protein_id="HBH0004789.1"
                     /translation="MKAELIKKEGNKVTLKITVDNNKFEAAVNKAYNKSRNKYNIPGF
                     RKGKAPRIVIETQYGKGIFYNDAIEILFPEVYPEAIKELDIDPIDNPDLDIEEISKDN
                     GLVMVLNVEVKPEFELGNYKGIEIAKVENTVSDENVDAKLQEMVEKNARLVSVEDKAL
                     EDGDTAIIDFEGFENGVAFDGGKGENYNLVIGSNTFIPGFEEQLVGKKAGEEVEVNVT
                     FPEEYHSQDLAGKPVVFNVKINDVKVKELSALDDEFAKDTSEFDSLDELKADVRAKLE
                     EEAKNRADAETRNSVVEKVAENTEIEIPEVMIQHQIDNMLNELNYQLQYQGFGLQQLL
                     EMTGRTMEELREERKEDAKKLVKSSLVLEAITKAEGIEATEEEFKAELEKMASAYNME
                     VEKIEASLRDADKEDIKGQIKIRKTIDLLVDNATIA"
     gene            complement(15997..16467)
                     /locus_tag="KR231_002423"
     CDS             complement(15997..16467)
                     /locus_tag="KR231_002423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HBH0004790.1"
                     /translation="MKIGIVSDTHMMIKNMEKTIPYLKECDLIIHAGDNFTDSRYIHS
                     MTNVGIIAVKGNCDFDAVEEEVVFEVANKTIFLCHGDKYGVKYGTHMLEKKATEVDAD
                     IVIFGHTHTPFREIKDGVLYINPGSTSLPRGVSYKSFVIMDIEEDDIKIEEIRI"
     gene            complement(16467..17816)
                     /gene="rph"
                     /locus_tag="KR231_002424"
     CDS             complement(16467..17816)
                     /gene="rph"
                     /locus_tag="KR231_002424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease PH"
                     /protein_id="HBH0004791.1"
                     /translation="MTRSYDRSNEQIRPVKITRDYTKYAEGSVLIEMGETKVICTASV
                     EEKVPPFLRNSGTGWINAEYSMLPRATQQRKIRDASRGKIDGRTQEIQRLIGRAIRSV
                     VDLNKLGERTIWVDCDVIQADGGTRTASITGAFVAVAEAIYKLYKAKIIKEMPITNFV
                     SAISVGIVNGIHMLDLCYEEDSKAQVDMNIIMTDKCEFVEVQGTGEEKPFSRADLNLL
                     LELGEKGNKELIRLQREALGEISDEILGMDYGNEVVIATNNAHKLEEIGEILKDFEYK
                     VYSLKDVDLAGIEIVEDGKTFEHNALIKARTIAKKTKLIAISDDSGLEVDALGKKPGV
                     YSARYAGEHATDEENRKKLLKAMQNIPMSKRNARFVSAIAVVFPDGKEFVVRGICEGM
                     IGFEEKGKNGFGYDSLFIVKGYDKTFGEIPSVIKNSISHRANALKLMKQEFIKRVVK"
     gene            complement(17976..20000)
                     /gene="ligA"
                     /locus_tag="KR231_002425"
     CDS             complement(17976..20000)
                     /gene="ligA"
                     /locus_tag="KR231_002425"
                     /EC_number="6.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent DNA ligase LigA"
                     /protein_id="HBH0004792.1"
                     /translation="MSVKDEINKLIETINYHNERYYNQDSPEISDYEYDKLMKELISL
                     EEEHPELKRIDSPTNRVGGKPLDKFNQIVHKTPMLSLSNAFSEQDLRDFDKRVQEYVG
                     ENVEYVVEFKIDGLSVGLTYNNGEFEKGATRGDGVVGEDISQNLMTVKSIPLKINDKK
                     ELIVRGEVYISKDNFRKVNEQQEEQEQPLFANPRNLAAGSLRQLDPKLTAKRPLDIFV
                     FNMENIEEYDLESHSESLEYLEKLGFSVSQSYKVCKSIDEVIEHIEYWTDNRGNLDYE
                     IDGMVIKVNNIKQRDEMGYTAKSPRWAIAYKFPAEKKKTKIVDIIVEVGRTGTITPSA
                     ILEPVRLAGTTVSRATLHNEDYIREKDIKINDTVLVQKAGDIIPQVLEVIKEERTGDE
                     IDFKMPEKCPVCSEPTIRLEGEAAVKCINMSCPAQIRRGIIHFVSRDAMNIDGLGESI
                     ITLLLNEKIIQDVSDLYYIKKEDVVDLERMGEKSADNLINSIEKSKENDLWRLINGLG
                     IKFIGVKAAKILAYNFKDLDEVISATSEQLEELEEFGSIMANSVVEFFKEDKNMNVIN
                     KLKNVGVNTKSLDNTGEKVEKIFEGMKIVLTGTLPTLKRNDAKDMIEKRGGKATSSVS
                     KSTTFVLAGEEAGSKLTKANDLGIKVIDEERFLELLKLSSKDEVKAVLES"
     gene            complement(20186..21124)
                     /locus_tag="KR231_002426"
     CDS             complement(20186..21124)
                     /locus_tag="KR231_002426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate dehydrogenase"
                     /protein_id="HBH0004793.1"
                     /translation="MKVLFTINYGKEKFDKIRELGYDVIHYSEDSIENNEDVNTADVL
                     VTYNPFERLDISKMKNLQYIQTTSVGIDQLPKEEVLKRNIKIANNRGGYSVPIGESIV
                     LYILEIYKNSAKFFKQQQNKEWKMDFSVSELYGQRVGFLGTGTISSEAAKRLKAFGVE
                     IWGVNTDGSSKKYFDKCFATEDMNIVFEECDIVVVAMPSTKSTDGIVNKDMFKLMKDG
                     SVFINVGRGNTVNQKDLEECVEKFRGVALDVFESEPLNKDNKLWECENVIVTPHNSWV
                     SDKNKERTFNMVYNNLKHYIMENKPVDNVVDISRGY"
     gene            complement(21226..21648)
                     /locus_tag="KR231_002427"
     CDS             complement(21226..21648)
                     /locus_tag="KR231_002427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3783 domain-containing protein"
                     /protein_id="HBH0004794.1"
                     /translation="MSFEKINNNNLDKIHNRKCIMLVNFNKKELSLIKNVSNFAGIRD
                     HIILSDKNGENIIRDILDGNISNECENGIKSKSVIFNNTPSTQVNAFLEGLKKVRINR
                     PFTAMVTETSIDWTLNNLIENLVQERNAMSLGKTIEHK"
     gene            21836..23119
                     /locus_tag="KR231_002428"
     CDS             21836..23119
                     /locus_tag="KR231_002428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugated bile salt MFS transporter"
                     /protein_id="HBH0004795.1"
                     /translation="MNTLLNNKFSIKNFSNAWVIVLGCMLIQAVPFSIVASIQPQFIS
                     YVVEGEGFSLASFSLIFTIGTIASAIASPFIGVLFSKVNIKILYLLGCIISSIAFATF
                     SICTELWQFYTVSCIVQIGATIISAIGIPVLISAWFDEESKGKALGFAFAGGSIGSIF
                     LQPLAVRLLATQGYSRSYLIFGIIALIVGIPVILFILRMPKDINEKVKSKGKKEKASD
                     TISPSVWGYTLKEAKKIKYFWIMTIGFIFVGIYVSSLSVQYPTYLRNYLNPILIGTVG
                     STFALFALIGNLFGGLLFDKFGQTKPLIISFVLVLIATLSLLLVDKSSTFAFVFAILK
                     GLSVFAYMIGPAYLTGSFFGQKEFGSIYGIVQLIFAVGFALGSTLFGLLVDNFGYRFS
                     WSIIILSVIIAYTLLIITSIGMKKLNKERLDKLMQ"
     gene            complement(23197..23712)
                     /locus_tag="KR231_002429"
     CDS             complement(23197..23712)
                     /locus_tag="KR231_002429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S dicluster domain-containing protein"
                     /protein_id="HBH0004796.1"
                     /translation="MNYFVIADPDKCIGCRTCMIGCVVAHSDEDIFYQNLDEINFNPK
                     LSVIKTKEVSAPIQCRHCEDAPCAKACPNGGIVRVGNTIKINEENCIGCKTCMLACPI
                     GAIDIVTLKDVDEGKLCFRERMTANKCDFCIESPEGPACVNVCPTKAFTIVKDEDIDS
                     KVKNKRKLAIL"
     gene            complement(23712..25088)
                     /locus_tag="KR231_002430"
     CDS             complement(23712..25088)
                     /locus_tag="KR231_002430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron hydrogenase small subunit"
                     /protein_id="HBH0004797.1"
                     /translation="MIINIDKDLCTGCRECSKVCPVNAIEGEEGKPQEINLDRCVMCG
                     QCVQTCKSYASVIDEGFEFLQEKKQEREIPESINEPIFAAYNVCDIDKVKKALSDPNV
                     FTMVQCAPAVRVALGEDFGYYLGYLGAGKMAAALRALNFDRVYDTNFAADLTIMEEGS
                     ELIKRVTEGGTLPMFTSCCPAWVKFMEKNYPKLTNHLSSCKSPQQMGGAIFKTYGAEI
                     NNVDASKIFSVSIMPCTCKKYECDREEMDSSGYRDVDVVLTTRELAYLIKDMGIDFKN
                     LREEKFDSPLGSYSGAGTIFGVTGGVMEAAIRTGYELITGESIPDVEVKQVRGENGFR
                     KSTIKIGDLDLRVGVVSGLKNVIPVLEDLEKGKLDVDFIEVMTCPVGCVSGGGQPKIL
                     LEEYKELAYENRTKATYVHDEHLAIRKSHENPDIKKLYDEYLVEPLGEKSHHLLHTTY
                     CIGKEVAK"
     gene            complement(25113..25664)
                     /locus_tag="KR231_002431"
     CDS             complement(25113..25664)
                     /locus_tag="KR231_002431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S dicluster domain-containing protein"
                     /protein_id="HBH0004798.1"
                     /translation="MKNKIGSFVIADPNKCTGCRACEVACFTMHNQHNNVGYTVGTVD
                     IPVIPRLYLVKGDNFCMPIQCRQCEDAPCLNSCPQKAIVKENNIMSVNEEKCIGCKTC
                     LLACPFGAIDLLPQYEDGKEVEQVILDENKKIAYKCDLCKDNEKIACISACPQEALKL
                     VTPIDDKKAKNRQAALSLLLTNK"
     gene            complement(25722..25937)
                     /locus_tag="KR231_002432"
     CDS             complement(25722..25937)
                     /locus_tag="KR231_002432"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0004799.1"
                     /translation="MQIHRELSKSENEYMCTKKEEQRYSKCEICGVLIDDTDKVYNNT
                     YNLCKKCKRNISTEKIVKYINIYDESK"
     gene            complement(25906..26739)
                     /gene="fdhD"
                     /locus_tag="KR231_002433"
     CDS             complement(25906..26739)
                     /gene="fdhD"
                     /locus_tag="KR231_002433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate dehydrogenase accessory
                     sulfurtransferase FdhD"
                     /protein_id="HBH0004800.1"
                     /translation="MNNIYSKTKLQENSKDKVFENSYSLVDYKYLNSFNVEVSKINEH
                     EVSIDNEEIIAEYPLSFILNDKYINTFLCTPYNLEELIVGFLKTKGYIENKKSLLKFE
                     INESERFAKVTIQEKQKNQDEQIIFLNSLDYITCAPVKSNIKINYDTIYSIMDRNLNS
                     SELFKNTGGVHSVSVFNFDKKIVTCEDVARHNAMDKAIGFCVLNDITLKDKIVAVSGR
                     ISLEMILKAAMTQIPIVVSKSAPTNLSIELSKKLNITLIGFVRGRRMNIYANPQRVIK
                     K"
     gene            complement(26788..28932)
                     /locus_tag="KR231_002434"
     CDS             complement(26788..28932)
                     /locus_tag="KR231_002434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_except=(pos:complement(28516..28518),aa:Sec)
                     /transl_table=11
                     /product="formate dehydrogenase H subunit alpha,
                     selenocysteine-containing"
                     /protein_id="HBH0004801.1"
                     /translation="MEKKILTVCPYCGAGCQLYLVVKDNKILRAEPANGRTNQESLCL
                     KGRYGWDFLNDPKILTPRLKKPMIRKQGVLEEVEWDEAINYTASRLNEIKEKYGPDSI
                     MGTGSARGPGNEANYIMQKFMRATIGTNNVDHCARVUHAPSVAGLAYSLGSGAMSNSI
                     PEIENADVLFIFGYNGADSHPIVANRIVKAKKNGAKLIVTDPRVTESARIADIHLPIK
                     GGTNMVLVNAFGNVLIEEGLYNKEFVQNHTQGFDEYKEIVKPYTAKYAEKITGIPEEL
                     IRKAMREYAKGKKAMILYGMGVCQFGQAVDVVKGLASIALLTGNFGRESVGIGPVRGQ
                     NNVQGACDMGALPNVYPGYQNVTDDKIREKFEKAWGVKLSPNNGYSLTQVPNLVLKEK
                     KLKAYYIFGEDPVQSDPDASEVREALDELEFVIVQDIFMNKTALHADVILPATSWGEH
                     EGVYTCADRGFQLMRKAIEPQGDVKPDWQIISEISTAMGYPMNYKNTKEIWDELRQLC
                     PSFLGATYEKIETQGCVQWPCKSESMEDKGTMYLYEGQKFSTPNGKGNLFAAEWRPPM
                     EVEDDEYPFSLCTVREVGHYSVRTMTGNCRTLSSLEDEPGRVQINSNDAEKLGIEDDE
                     LVRISSRRGSVITRATVTDRVKEGATYMTYQWWVGACNELTIANLDPISKTPEYKYCA
                     VKLEKLEDQELAEKCVREEYQSLKDKMTATNI"
     gene            complement(29183..30241)
                     /locus_tag="KR231_002435"
     CDS             complement(29183..30241)
                     /locus_tag="KR231_002435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flippase-like domain-containing protein"
                     /protein_id="HBH0004802.1"
                     /translation="MDRLKNIRKSLLQYTFLFLLIGITIYLVFKTLDIKMLSNVMVMV
                     DKKFLFIGALAIMCHIMLEGVVMKIIIESTHKVNIRFIGFKLAIMGFYYNLITPFASG
                     SQPVQIYVLKKCKMPLSKASAVVTNKSIIFQIVVTFYCTILVLMNFAMLEKQMKMIMP
                     LVFLGIAINSFVLIMIILVILNPKKIKYFMRITIKHLSKIKFLKFLDNKIESIESFID
                     DYSKAINFFAKNKKVLISTIIVTFIQLSAYFSVSFWIYKAFNLQGYSYIYILTLQAFL
                     YMAISPIPTPGNVGANELAFFTIFKSVFPQPLMGYAVFLYGGFMYYLILIGSGIFTVI
                     THYRMKNRIGRNIVLSEN"
BASE COUNT         9161 a         5457 c         3303 g        12486 t
ORIGIN      
        1 aaaattattt tctactttta ctttatcttt taatcttaat ggatttactt caatagattt
       61 atctgtatat ttaaagtatt cttcaataaa acaattttct ataccatagt aataaacata
      121 cttaaaatcc cttaataatc tttttatgaa ctcatatgat tttccctctt ttgatagcaa
      181 gtatgtttct cttatttttt tatcttttgt tatatttata attaactgac tttttttaca
      241 ttctataaat accccttctt ctgaaaaatt ctctattaaa tttaagttta taagcttttg
      301 taatatatca aaatttatat ttatagtctt tggattcata tttagatttt ctgaaatgtt
      361 cttaattaat tgaataatac tctttgggaa aagaattact tgtatattca atttatcatt
      421 tttagaattt ataactttat attttattga atagttattt atgtttattg gaatgtattg
      481 tgttatttca aattcaatca tgcttaatat gtctcttttt ttcttagtat ttagaacttc
      541 aacatttcta atgactatat cctgaatttg aatgttaaag tataaatttt tatataatat
      601 ttttgattta ccaatctcct cttttacaaa tctaactaca tcttctatat atttaatctt
      661 ctcaatcgaa ttactatcat tttttatatc aaagttaatc tcttttataa ttgatttatc
      721 tataaaaact tttttatgac tttttcttaa aaatacaagc cttatataat catcatttat
      781 ttctaagttt agaatttttt taattatagc catctccttc ttaaataaaa ataattttaa
      841 aacttacagc aatcaatata aaatattatt ttggataaaa ttgcttagaa tttatattta
      901 cgcttatatc tgttccgcta tcatttatga caagttcgaa tttacctgat gtactctgag
      961 gaactggaac agtatttagg tatccctttt ccttcaatgt ctctacactt agagagtcta
     1021 ttgtcttttc atcatcatta attgccatgc tagctgcggt tactatatta gcagcattcg
     1081 tatagtctgc atttaatttg gcactttctt gaaccttact atacttaact aatgctatac
     1141 tagatataac gcctaaaata gttactacta caatcatttc aacaagtgta aatccttttc
     1201 gttttttatt tatcaaattt atcaattaaa tattctctcc ttttcaaaag tttcatctaa
     1261 taaaatttat ttttctctct aaaaattagt aattgcatca aacataggaa caaccattgc
     1321 taaaataaaa gtaccaataa ttaatcccat aaatacaatt agcataggtt ctataaattt
     1381 cattatttgc tctattttgt tatttaattc attttcataa aatttattta ttacatttag
     1441 acttttatct agtttcccac tttcttctcc tgtatttgcc attgaaataa ataattttgg
     1501 aaaaacattt gctaaattca aagatttacc tatgctattt ccttttttta tataattatt
     1561 ggaaatcttt aacctttcat aaataaattc gttgtctata acactagctg acatgtctat
     1621 agcttccaca atttgtattc cactgctaat taaaacggac aatgcccttg aaaatcttgt
     1681 tgtagctact aactgattaa ttttttttat aaaaggtatt ttgaatttta acgaattaat
     1741 caattttttt atattatcat ttgttataaa gaaataaatg cttcctattg aaaacaatat
     1801 aaaactaaat attatataag ctaagttatt tgtaaccact gtagatattc ccattaaaac
     1861 tctagttatt aaaggtggtt caattccatt gttggtaaaa accacctgaa aattaggtat
     1921 tacaaatacg aatataaaca acattgataa gatagataat attataagta ttattggata
     1981 tattgaaata gttattattt tcatttttaa tttgtattct ttatcataat aattagataa
     2041 atcactcatt attatatcta agtttccact agtttctcct gcttttatca tacttataaa
     2101 gaatttagaa aatatacctg ttatttgaaa tgattctgct attgagttac ctttttgaat
     2161 atgatttgat actatactaa gcaaattctt tgctttttta cttgactgac tctcaatgat
     2221 ttcaaatatt tttgtaattt cacatccaga ttccagcaat atgcctatct ctttgcaaat
     2281 tactctaatt tctttatcac tgattctatt taatactaaa taaaactttt ctaaattata
     2341 aaatatattt ttagataatc tcatgtacta taataccttc caaattatat taattacaat
     2401 taaataaact taatattttc taatttaatg catttaattt tatttcactt aaatataatt
     2461 tatactcaaa catcttaatt aaaatagatt aaataaagac aactgaccaa acgaagttta
     2521 actatacaat tcagttaaat catttcattt actactaaac actcttctaa tgtcgttatt
     2581 ttttcattta ttagtctttt acaactatct tcaaatgtta tcattccatt attttgtgct
     2641 acatctttaa tagtactaga atcctccata tttcttatac atgtctttat atcatcatta
     2701 atttctaaga tttcataaat tgctgttctt ccaaagtatc ctttatcatt acatttttca
     2761 caccctacag ctaccttagt atttacatct ccactaaaat tatcttttat cataatctca
     2821 tggctacaat gattgcagac ttttctaacc aacttttgag atataacacc tataagagaa
     2881 gcatttaaaa gatatggtgg tatttgcatt tctagtaatc tagctatgga agatactgca
     2941 tcattagtat gtaaagtact tataactaaa tgacctgtta tagctgctct tactgctatc
     3001 ttagctgttt ctgcatctct tatttctccg accattatta tatctgggtc ttgtcttaat
     3061 atcgctctaa gacctacatc aaagctcaac cctacttttg aatttacttg aatctgactt
     3121 atgccatcca tcttatactc tacaggattt tctatagtca taatattttt atttattcct
     3181 tttaaatcat ttaataagga atatactgtt gtagtctttc cactacctgt aggacctgtc
     3241 actaataata ttcctgctct tttatttatt atacgattta tagattttat agcttcctct
     3301 gaaaaaccaa gttctaattt gtcttttaaa aaagtatctc tattaagtat cctcaaaact
     3361 attttttcac catagacagt tggtattgat gaaactctaa tgtcaattaa atttccacct
     3421 aactttatat ccaccctacc atcctgagga agcctttttt ctgttatatc cattgatgcc
     3481 tttaatttta taaccgtaga caatgatgga tagacatcaa ctaaaaactt tgatacttcc
     3541 tttagttctc catctaccct cattctcact attaaatgtt ctttaaatgg ttctatatgt
     3601 atatcacttg cgttttcttt tatagctttt tctaaaagat tttcaaataa tttttttgca
     3661 taatcctcat caagttcaaa gctattataa tatttttcaa tcttttcact tataagttct
     3721 tttttctcct tcttcaatat aatttcttta cctgtagcta atctcaagtc ctgtagagca
     3781 taaatatcct catcttctat ttctacaact aaattatcat cttgaaactc aactggaaat
     3841 acattatatt tttttgcaag tttttctggt attaacattg gcaaactgct ttcctctaat
     3901 ataatcttaa tcacccttta tatactttaa tttattaggt atattcattt ttttcataga
     3961 gatattttct tcagttttta tgcttatttt cattggataa ttggtttgta tgctatctaa
     4021 atatttacta cctttatcta cataattaga tagtttctcc ttatctccaa tgcactttat
     4081 ttcatatggt tgtgctacag gaactccatt tatatttata tggcttcctg caagtacaac
     4141 ttctgaatat tgattaattc tttgaccatt tatttctatg tattttcctc cgtttacttt
     4201 taattcattt ataactttta caagaatctt attatagtct atactattag ctatattccc
     4261 tgttttttca tctatagcat ctatacttaa tattatccca ctacccttta catctgaata
     4321 tgatagacta tctctaagtg tttctatttc tgatatttct tcagaatttt tttgattttg
     4381 tttcattgaa ttaatttctt tatctaactt gtctttctct ttggttaatt cttttataga
     4441 ttttcttgtc atttttattt cttttcttat tgacttgtct ttgcttgtat aaactgtttc
     4501 ttcattgcta taatctctaa atatggttcc aacaagtata cctaaaatag tacttgctag
     4561 tattataaac acatattgtt ttttcatact gtattgctcc ttacaaattt atttttatat
     4621 gataattttc tttaattaaa tattaaacat ttacatatgc ttattatatc aaagttatat
     4681 attaaaattc atctttagta tataatatca tacattgaac tcctatcact aatttaccaa
     4741 tatcaagtat gcatttttag atgttcttaa aattatataa actttcaata aacattgttt
     4801 tgatattata aaaaaacata aattaggaaa ggaaataata attatgaaaa acaaataatt
     4861 gctttggaga ttattaatat cattttttag caaaaaaaag taaaatggca tagcctcaaa
     4921 gctacaccaa tttactaaaa attatatcat tattaacatt aattttaaac atatacgttt
     4981 ataagttttc ctcatatttt aaaattcttt taattaattt atctcttaat ttccctactt
     5041 catcaaatct catattagga ctatagtaac tttctataat atcatgttta gacttggctc
     5101 tcttaagatt tagtactgcc caacaaatta aatcatctaa aactttttca tcaaatttaa
     5161 tatcttcttc atatttaagt agtttttctc tatttaaaaa ctgatttaaa tcaattgtat
     5221 cttcttcttt aaaagtcgta cttatagtta tgcctatatc taaatcagtt aatagtacag
     5281 tttcaatttt ctctggaata agtggataat gataaacttc tacatttaaa cctttttcaa
     5341 tagctttctt atatactttg tttaataatg tagttttccc agttcctatt tctccatcta
     5401 aataatagac tttctttaca tcttttaaaa tgttttctgt ataatctaaa caccctacag
     5461 gagttatagc tgaaccaaat aaatgctttt ctctttttag atttcctgtg cttttaactc
     5521 catcaaataa cctttttata aattcttctg tgaccaaatt tactttgcca taatccatac
     5581 aatcagaata tttttcttct atgtctctaa agattggttc tgctgatttt aaaaacttaa
     5641 atgctctttt aaatgaatta ctaatatctt tatcataaac tgatatttct tgtttattct
     5701 tttctaattc ttctgtattc cagtaatcac ctaaattaat tatctcatcc aaagctccag
     5761 gtagctttgg gtccatagta tgtggggcag ttgcatccat aagtaccacg cctaatttct
     5821 ttataactaa accatccaac gaacttgggt cagaaggaca atgatataaa tcaatatcat
     5881 atcctctatg caaaaactct ttataaattt ttttcataag tgaggatttt cctactccag
     5941 gtccaccctt taaacaaaaa actcttttta cattttcagg aattatatag tcaaaaaaag
     6001 aatatgagcc ttgtgatgta tttccacccg ggaatgcctt ctttaccttt ccttccatat
     6061 tagcgcctcc tcataattta caatatctct taattaagat attcatatta taagaatttt
     6121 attacagctt tctgattttg acaaatttaa aacttgccat ctaatactaa taacaggtta
     6181 attttatcta attattatag attctcatac tgtgccttat tctatctata aatacaattt
     6241 aagtgtccat attgaaatat ttgtattgta atacagctgg atattactta aatccaattg
     6301 tttccattat aattttatgt taaaataata ttacaaaata catctgtttt tcttcataaa
     6361 cgggtgaaat tacctatcgg cggtaaaagc ccgcgagcct tatggcataa tttggtcata
     6421 ttccaaagcc gacagtaaaa tctggatggt agaagaaaat agtatatgag tacctttatg
     6481 taattttaca tgagtaatct atacaaatcc ttcaactacc gtatttattc atgaaattag
     6541 acacattcaa ggtacctaat atacaggtgc tttttttgtt gtttatttta caattatatc
     6601 gtacttataa aatctattaa gattggagtg ttatcatgaa acaaaaatgg atagtattga
     6661 ttatcatctg tattggtgta tttatgtcta ctcttgatgg aagtatacta aatatcgcaa
     6721 atcctacaat tgctgctgac tttaaaatta acatgtcaca aattcagtgg gttgtaacag
     6781 cttatatgct tgttgtaaca gctactatgt tatttttcgg aaaacttggc gataaagtag
     6841 gttcaaatcg tctatacaca ttaggatttt ttatatttac aataggttct tttctgtgta
     6901 gtatgtcaaa caatttatca acattaattt cttcaagaat ctttcaggca gttggagcaa
     6961 gtattttaat ggctactggg cttggtatag tttccaatgc atttccagca aatgaaaaag
     7021 gaaaagctat aggaatcact ggagctgtag ttggtatagg aaatatgagt ggtcctgtaa
     7081 ttggaggtat aattttagaa cattttggat ggccttctat ttttattatc aatatcccta
     7141 ttggtattat agcagtcttt cttggcatta aatttctgcc taaacctgtt ttggatgaac
     7201 aaaacaagag ctttgatatt ccaggtcttc tacttttcgc atcttgcact acgcttatat
     7261 tacttgcaat gaatgagaag ggtaatacaa gattgtattt aggtataaca gcacttataa
     7321 tcttcttatt gttggcatta agagaagtaa aatttgaaca aagctttatt gacctccctc
     7381 tatttaaaaa tagaaacttt actgtaggca atatcattgg agtagcttgt tattttcctc
     7441 aaatggcagt atcttttcta cttccatttt atttagaaca attaaaaaat ttatctccta
     7501 tgatggctgg ttatgtaatg actgtacatc cacttattat ggtacttata gcacctattg
     7561 caggttcact ttctgataaa cacggtgcaa aaaacattct aacagcatct ttttcattta
     7621 tgaccatctc actagttgga atggcacttt taaaagcaga ttctccattg taccttttaa
     7681 ttgtatgttt agttattttt ggacttgggc taggagcatt tagttcacca aacaatagta
     7741 gtattttagc agatgttcct cctcaaaaac aggggtacgg aggcagtttt cttgcaacta
     7801 ttcgtaattt atcatttgct cttggaacag cattttttag tagttttttt gcacaaagtc
     7861 ttacatacaa tcaaaagttt aaaagtcaca catcagccta tgttatagct agcaatcagt
     7921 cttattggat tgcagcatca gtatgttttg tagggcttat actaactgtt ttctttatga
     7981 ggaaaacaga taaatctatt tcttaaatgc tatttattac tgactacata aatcaataat
     8041 tttttagttt aactatttta tactaatttt cccatacctt actaaaattt attagtattt
     8101 agcaaaatta ctgatattta ttgtttataa acaataagga tgccaaaaaa aagttcatta
     8161 aaactatttt aaggcatcct atattttact ttaatattaa tataattaaa actaactatt
     8221 attacattta ttattcaaat aaatcttatg tcaatattta acattttaaa tttaatctac
     8281 tgttatttca tatccatgtt gattgtattg atttacaatc tcttcccata attcttcaac
     8341 accagtcttt tttagtgaag aaacaggaat tactttttca ctactttcca tttgcaattt
     8401 ttttcttatt atacttatgt gtttttgata ttgtcctcta gatattttat ctgccttagt
     8461 tgcaataact acacagttat atccaaagtg ctttatccat tcatacataa gcttatcatc
     8521 tgctgtaggc tcatgtctaa tatctacaag taggaatata gaacataact cttgtctact
     8581 ttctagatat cgttccatta tacctcccca cttttctttt tcagacttag ctatctttgc
     8641 atatccatag cctggaaggt ctacaaaata aaattcatta tttattagat aaaaatttat
     8701 agttctagtt tttcctggtg tttgactggt tctagcaaag tttcttctgt taagcaatgt
     8761 atttattatt gatgattttc caacatttga cctaccagcc aatgctatct ctgggattcc
     8821 ttctgctgga tactgtgatt tattcacagc actcatagtt atctctgaac ttctaatttt
     8881 cattattttc accactcttt aataaagctt gttctaatac ttcatccata tgttctacaa
     8941 gcacaaactc cattttttct tttacatttt ctggtatttc atctaaatca gcttcacatt
     9001 ctttaggaat taatactttt gttataccag ctctatgagc tgctaataac ttttctttaa
     9061 ctcctcctac tgctaagact ctacctctta aagttatctc tcctgtcatt gctatatttc
     9121 caggcacagg tcttttagta agtgctgaga ttactgcaag agccatagtt ataccagctg
     9181 atggtccatc ttttggaaca gcaccttctg gaatgtgtat atgaatatca ttcgtcttat
     9241 aaaattcagg gtctatatca aacttgtcca ctattgacct tatataagag atacctgtct
     9301 tcgcagattc cttcataaca tctcctaatt ttccagttaa tacaatttcg cctttacctt
     9361 taagtacgtt tacttctact tcaagtgtaa ctccaccaac ttctgtccac gcaagaccat
     9421 ttactaatcc tatttgaggg ttaacttctg caagttgata cttaaacatg tcttttccaa
     9481 gatatgtctc taggtcagac ttatttataa caacctcttc aagagttggg tcttcaacgt
     9541 attttttggc aacctttcta caaatcttac caatagttct ttctagtgtt cttacaccag
     9601 cttctcttgt ataatggttg attatacttc ttaaagtttc atcatctatt tttataaagt
     9661 tttcttttaa agcatgttct ttaatttgtt ttggaagtag gtattttttt gctatattta
     9721 atttttcttc ttctatatat ccagatactt ctattacttc cattctatct aataatggtc
     9781 ttggtatatt acttagacta tttgctgttg taacaaatag tatttttgat aaatcaaaag
     9841 gtatttctaa gtaatggtcc acaaaatcct tattttgctc tgggtctaat acttctagca
     9901 ttgctgaagc tgggtcacct ttataatctg ctgccatctt atctatctca tcaaataaga
     9961 atacaggatt ttttgtttgg gcttctttta ccccattaat tattcttcct ggaattgaac
    10021 ctacataagt tcttctatga cctcttattt ctgcttcatc tctaactcca cccaaagata
    10081 ttcttacaaa ttttctattt aatgctctgg cgattgattt tactatagat gtctttcctg
    10141 ttcctggagg accaactaga catattatag gccctttaag tgacttagca agagttctta
    10201 tagctagata ctctagtatt ctctccttaa ctttttctaa tccataatgg tcttcatcta
    10261 atatatcttt tgccttagtt atatctaatt tatcttttgt ctctttattc catggcaatg
    10321 agaatatagt atctaaatag tttctactta cagatacatc tggagacata gaagatattt
    10381 ttgaaaattt atctatctct ttttctattt tctctttagt tgtcttaggt gcttttattt
    10441 ttttaagctt ttctctatac tcatctgctt cagagtttat atcttcttct tcacctaatt
    10501 ctttctgtat agcttttaat tgttctctaa gataatattc tttttgaacc ttattcatct
    10561 gtttttttac tcttaaagtt attttctttt ctatttttaa tatatctatt tcctctaata
    10621 atatagaata aataagttca agtctttttc taatatcaaa ttcttctaat atttcttgtt
    10681 tttggcttga ttttagatat atgtttgcag ctatcgtatc tataaatcta tctacatctt
    10741 ctatatcagc taaagatatt aatatttctg gtgataccct atttccaata tttatatact
    10801 cttcaaaggc atcaaataca tttcttacaa atgcttcaat ttcaacttct gtttcactat
    10861 ccaaattatc actatcaaat actatttctt ctattactgc tctgaaatac ccatcttctt
    10921 gttctatttt ctttactcta ccccttgata caccttcaac caaaacacga actgtatctc
    10981 ctggtaattt tatcatttgc ttaactttac agattgttcc cacatgataa aaatcctctt
    11041 ctcctggctc atctacctct gcttctttct gagaagttaa aaatataagt tcttcatcca
    11101 tcatagcttg gtctaaagct ttaagagata tctctctacc tatatcaaaa tttaatatca
    11161 tatatggaaa tatagctaat cctcttagag gaattaatgg taattcatga tctattttag
    11221 tataattttg ttccatcaac attactcctt ttctagtcta attgctttgc ttttaatatt
    11281 atatatttga acaagttaat tttcaacatt aatgataaat tcttagaata ctatcatact
    11341 atattatctt tttattatga tataatatta atattagtat acttagatgt tatttatctt
    11401 ttggaggttt ctattatgtt gaaattgttt ttaacctttt taaaaattgg tgcgtttaca
    11461 tttggtggtg gatacgctat ggttcctctt atacaagatg aacttgtaaa caaacaaaaa
    11521 cttttagagc aggaagaatt tattgattat ttatccatag ctcaaagtta tcctggagta
    11581 ctggcagtta atatatctgt attattagga tataaacttt atggtatacc aggagttctt
    11641 atatgtacct taggctctgc tttaccatca ttttgtatag tcttagtctt atcgtatcta
    11701 tactttaaaa attcatcatc taaaatttta gatggatttt ttaaaggagt tgcgcctgtt
    11761 gtaatagctc ttatattgta ttcttttacg agcatgttca agaaactacc aaagtctaaa
    11821 actaacatac tactattaat tatagcagtt ttatctgttg gtgtattcaa tataagccct
    11881 atttatttaa taattggagg aggtgtatat agtctatgtc agaaataata ctactcttct
    11941 taatattcct taaaataggg gcatttagtt ttggtggcgg ttatgccatg ctaccattta
    12001 tccagcaaga atttatatct aaatatcact ttataactaa tcaagagttt ttggatttac
    12061 ttgctatatc acaatctaca ccaggtcctg tagcaataaa tagtgctaca tttgtaggat
    12121 ttaagactgc tggcttcttt ggttctctag ccgcaactat tggtgttaca atttttgcat
    12181 taataggtct aactattata tcaaagttat tttctaaatt taaaaataat aaaaaggtag
    12241 aaaacttatt gacagttctt agaccaatta ctctaggatt catattatca gcagcttttt
    12301 catctgccaa agaagttaat tgggatttat atggaataat tgcatttata gcatcatttt
    12361 atcttttata taaaggaaaa attggttcca ttgcaattgt attcgtcttt ggtattctag
    12421 gtatattact cacattttta taataatgat acctatttta tatttagcat attaacataa
    12481 aaaaaggagc ttttaaagct ccttttcatc atcttatgca ctttcctctt gatccttaag
    12541 tactatgata ggatttactg agtcttcgtt cacagatttc tctgttacta taaccttctt
    12601 tatattatct ctagatggta cttcaaacat agtttccatc attacgcttt caactatact
    12661 tctaagtcct ctagctcctg tatttctttc tatggccttt ttagcgattg cacgaagagc
    12721 accttcttca aattctagct caacatcatc taactccaat aactttttat actgttttac
    12781 tagagcattt ttaggttcct gtaatatctg cattaatgca tcttcatcca acaactctaa
    12841 agtagctaaa actggtattc ttcctataaa ctctggtatt ataccatatt ttaataaatc
    12901 ctctggaagt actttttcat atagcttccc taaatctaat tcttttttac tttctatttt
    12961 agctccaaaa cctagtgttt tatctccacc acgtttttga attatcttct ctaatccatc
    13021 aaaagctcca cctaatataa ataatacatt agtagtatct atctttaaaa attcttgatg
    13081 aggatgtttt cttcctcctt gtggtggaac atttgcaaca gtaccttcta atatttttag
    13141 aagtgcttgt tgaacacctt caccactaac atctctagtt atagatgggt tttcagattt
    13201 tcttgcaatc ttatctatct catctatata tattatacct ctttcagctt tttctatatc
    13261 aaaatcagca gcttgaataa gttttaaaag tatattttca acgtcttctc caacatatcc
    13321 agcttcagtc aatgatgtag catctgccat tgcaaaaggt acatttagag ttcttgctag
    13381 agtttgagca agtaatgtct ttccagaacc tgtaggtcct aataaaagta tattactctt
    13441 ttgaatttct atatccttac tactagattt tttactgtat attctcttat aatgattata
    13501 aaccgcaact gataaagctt ttttagcttt ttcttgacct attacataat catttagaat
    13561 ctccatcatt tcctttggtt ttggtaaaga tgtagtatcc tcatctatag tatcttctat
    13621 ctcttcttga ataatttcgt cacaaagttc aacacactcg tcacaaatat atacatttgg
    13681 acctgcaatt aatcttctta cttgatcttg atttttaccg cagaatgaac actttaattg
    13741 tcgtttttct tcatatttag acatattaac acctctctct atctacggtc tctttgtaaa
    13801 tacttcatct attaaaccat attctttggc ttctagtgca ctcatgaagt tatcacgttc
    13861 agtatccatt ttaatttttt ctaatggctg accagttctt tcagataata tctcatttaa
    13921 agtttctttt atttttaaaa ttctctttgc atgaatttct atatctgttg cttgaccttg
    13981 agctccacct aatggttgat gtatcattat ttcactattt ggtagtgcta gtctttttcc
    14041 ttttgctcct gctgccaaca agaatgctcc catagaagca gccataccta tacatatagt
    14101 acttacatct ggtttgatgt attgcatagt atcatatata gccattccag aagttatact
    14161 tcctcctgga gaatttatat ataaatgtat atctttgtct gggtcttcag cttctaaaaa
    14221 taatagctgt gctactataa gccctgctgt ggcatcgtta acttgatctc ctaagaagat
    14281 tattctgtct tttaatagtc tagaaaaaat atcataagat ctttctcctc ttcctgtttg
    14341 ttcaacaact acaggtacta atgccatggt ttcatacccc ctttattcta tataatttac
    14401 agtagctttt tttaagctac tgtaaattat tatacgcatt taactaaatt atatttgcac
    14461 atcattatat actaaacatt tcataacgtc aactatatta gttagcgttt attttattaa
    14521 gctattgttg cattatcaac taataaatct attgtttttc ttatttttat ttgacctttt
    14581 atatcttctt tgtcggcatc tcttaaagaa gcttctattt tttctacttc catattgtaa
    14641 gcagaagcca ttttttctaa ctcagcctta aattcttctt ctgttgcttc aattccttca
    14701 gctttagtta ttgcttctaa tactaaagaa gacttaacta attttttagc atcttctttt
    14761 ctctcttctc ttaattcttc catagttcta ccagtcatct ctagtaattg ttgtaatcca
    14821 aatccttgat attgtaattg gtagttaagt tcatttaaca tattatctat ttgatgttgt
    14881 atcataactt ctggtatttc tatttctgta ttttcagcaa ctttttctac tactgaattt
    14941 ctagtttctg catctgctct atttttagct tcttcttcta acttagctct tacatctgct
    15001 tttaattcat ctaaagaatc aaattcacta gtatctttag caaattcatc atcaagtgca
    15061 gataattctt ttacttttac atcatttatt tttacattaa atacaactgg ttttccagct
    15121 aaatcttgtg agtgatattc ttctgggaaa gtaacattaa cttctacttc ttcaccagct
    15181 tttttaccta ctaattgttc ttcaaatcct ggtataaatg tgtttgaacc tataactaag
    15241 ttataatttt cacctttacc accatcaaaa gctacaccat tttcaaaacc ttcgaagtct
    15301 attatagctg tatctccatc ttctaaagct ttgtcttcta cacttactaa tctggcattt
    15361 ttttcaacca tttcttgtag tttagcatca acattttcgt cacttacagt attctcaacc
    15421 ttagctattt ctataccctt gtagtttcct aattcaaact ctggtttaac ttctacatta
    15481 agaaccataa ccaacccatt gtctttactt atttcttcta tatctaaatc tggattgtct
    15541 attgggtcta tgtctaattc cttgatagct tctggataaa cttctgggaa taatatttct
    15601 atagcatcat tgtagaatat accttttccg tattgagtct ctataacaat tcttggagct
    15661 ttaccttttc taaatccagg tatattgtat ttatttctgc ttttattata agccttattt
    15721 actgctgctt caaatttatt gttatctact gttattttta aagtaacttt attaccctct
    15781 tttttaatta gttctgcttt catccttcta atcctcctag tgatatttat gtaatacccg
    15841 ataacggtat tataattcat tctatttata attcaaccac ttaattatat cacataagtt
    15901 tttttattta caagtgttcc attaatatcg ttgtacttat ttgataaaat ttaatttttt
    15961 gagcgttttt tgccattttt ttagataaat acacctttat atgcgtattt cttcaatttt
    16021 tatgtcatct tcttctatat ccataatgac aaaactttta tacgatactc ctcttggaag
    16081 tgaagtgctt ccaggattta tgtaaagtac accatcttta atttctctaa atggggtatg
    16141 ggtatggcca aatataacta tatcagcatc aacttcagtt gccttttttt ctaacatatg
    16201 agttccatat tttacgccat acttatctcc atggcataag aatatggttt tatttgccac
    16261 ttcaaagaca acttcttcct caacagcatc aaagtcacaa ttacctttaa ctgcaataat
    16321 acctacatta gtcatgctat gaatatatct tgaatcagta aagttatctc ctgcatgaat
    16381 tattaggtca cattctttca aatatggtat tgttttttcc atatttttaa tcatcatatg
    16441 tgtgtcgctt actatgccta ttttcattac ttcactaccc tttttataaa ctcttgtttc
    16501 ataagtttta gtgcgtttgc tctatgactg attgaatttt ttataacact aggtatttca
    16561 ccaaaagtct tatcatatcc ttttactata aataagctat catatccaaa accattttta
    16621 cctttttctt caaatcctat cattccttca caaattcctc ttactacaaa ttcttttcca
    16681 tcaggaaaaa ctactgctat tgcagagacg aatcttgcat ttcttttgct cattggtata
    16741 ttttgcatag cttttaacag tttttttcta ttttcttcat ctgttgcatg ttctcctgca
    16801 tatctagctg aataaacacc aggttttttg cctaaagcat ctacttctaa gccagaatca
    16861 tctgatattg ctataagttt agtctttttt gctattgttc tagcttttat caacgcatta
    16921 tgctcaaatg tttttccatc ttctactatc tctatacctg ctaaatcaac atcttttaaa
    16981 gagtacactt tatattcaaa atcttttaag atttcaccta tttcttctag cttatgagca
    17041 ttattagtag caatcactac ttcattacca taatccatac ccaatatctc atctgatatt
    17101 tcacctaaag cttctctttg aagccttatt aattctttat tccctttttc acctaactct
    17161 aacaataaat ttaaatctgc tctcgaaaaa ggtttctctt ctcctgtccc ctgtacttct
    17221 acaaactcac acttatcagt cattattata ttcatatcta cctgtgcttt agaatcttct
    17281 tcataacata aatctagcat gtgtattcca tttacaatac caacactaat tgcagacaca
    17341 aaatttgtta ttggcatctc ttttattatc tttgctttat ataatttata tattgcttct
    17401 gcaactgcta caaatgcccc tgttatagat gcagttctag ttccaccatc tgcctgaatc
    17461 acatcacaat ctacccaaat agttctttct cctaatttat tcaagtctac aacagacctt
    17521 attgctcttc ctattaacct ctgtatttct tgtgttcttc catcaatttt tcccctagat
    17581 gcatctctta tctttctttg ttgtgttgct cttggtagca tagaatattc agcatttatc
    17641 catccagtac cactatttct taaaaaagga ggaacttttt cttccactga tgcagtgcat
    17701 ataacctttg tctctcccat ttctataaga acagaacctt ctgcatactt tgtataatct
    17761 ctagttatct ttacaggtct tatctgttcg ttacttctat cataacttct ggtcattttt
    17821 tatatccttt ctcatatttt ttatttttta taaatttatt tttataattt ttaattttgt
    17881 caaatattaa ttattgtcat ttttcgtaat cttattagct tactgaacta ttctatcatt
    17941 aattatagta gttttctact aaattaagcg actttttaac tctctaatac agcttttact
    18001 tcatctttcg atgataactt taataattct aaaaatctct cttcatctat aactttaatt
    18061 cctaaatcat ttgctttagt aagtttagaa ccagcttctt cacctgccaa aacaaatgtt
    18121 gtcgatttac taacactaga tgtagctttt ccacctcttt tttctatcat atcttttgca
    18181 tcatttcttt ttaatgtagg aagtgtacca gtcaatacga ttttcatccc ttcaaatatt
    18241 ttttctactt tttcacctgt attatccaat gattttgtat ttactcctac attttttaac
    18301 ttgtttataa cgttcatatt tttgtcttcc ttaaaaaact cgacaacgct gtttgccatt
    18361 atacttccaa attcctctaa ttcttctagt tgctcactag ttgcagaaat tacttcatct
    18421 aaatccttaa agttatatgc aagtatctta gctgctttaa ctcctataaa tttaatacct
    18481 aatccattta taagtctcca taaatcattt tcttttgatt tttcaattga atttattaaa
    18541 ttgtcagcag atttttcgcc cattctctct aggtcgacta catcttcctt ttttatataa
    18601 tataaatcag atacatcttg aataattttt tcatttaata gcagtgtaat tatagattct
    18661 cccaatccat ctatattcat tgcatccctt gacacaaagt gtataattcc ccttcttatt
    18721 tgggctgggc aagacatatt gatacatttt acagcagctt ctccttctaa tcttattgtt
    18781 ggctctgaac aaactggaca cttttctggc attttaaaat ctatttcatc tccagtacgt
    18841 tcttctttta taacttctaa aacttgaggt attatgtccc ctgctttttg aactaatact
    18901 gtatcattta tttttatatc tttttctctt atataatctt cattgtgaag tgtagctcta
    18961 cttacagtag tacctgcaag tctgactggt tcaagaattg ctgaaggtgt tattgtacca
    19021 gttctcccaa cttctactat tatatctact attttagttt tcttcttttc tgctgggaat
    19081 ttatatgcaa ttgcccatct aggacttttg gctgtatatc ccatttcgtc tctttgtttt
    19141 atattgttta cttttattac cataccatct atttcgtagt ctaaattacc cctgttatct
    19201 gtccagtatt caatatgctc aataacttca tctatacttt tacaaacttt ataactctga
    19261 cttactgaaa atcctagttt ttctaagtac tctagtgatt cactgtgact ttctaaatcg
    19321 tattcttcta tattttccat attaaataca aatatatcta atggtctctt tgctgttagt
    19381 tttgggtcta attgtctcaa tgaaccagct gcaagattcc ttggattagc aaataatggc
    19441 tgttcttgtt cttcttgttg ttcatttact tttctaaaat tatcttttga tatatatact
    19501 tctcctctaa ctattagttc ttttttatca tttatcttaa gaggtatgct ttttactgtc
    19561 attaagtttt gagaaatatc ttctcctaca actccatctc ctctagttgc tcctttttca
    19621 aactctccat tgttataagt tagacctaca gaaagaccat ctattttaaa ttcaacaaca
    19681 tattcaacat tttctcccac atattcttga actctcttat caaaatctct caaatcttgc
    19741 tctgaaaaag catttgataa actcaacata ggagttttat gtacaatttg attgaactta
    19801 tctaatggct tacctcctac cctatttgtt ggagaatcaa ttctctttag ttctggatgt
    19861 tcttcttcta aagaaattaa ctccttcatt aacttatcgt attcataatc tgatatttct
    19921 gggctatctt gattataata cctttcatta tggtagttta ttgtctctat aagtttatta
    19981 atttcatctt ttacgctcac tttttgcacc tcttcatatt tttaaaatta aattattttg
    20041 aaatttccct ataattaatt atctcctatt tatatatttt ttagtatatc actttttggg
    20101 ctttaaattt attacaaaaa aaactcttat tagtatcttt aatacgacta ataagagttt
    20161 ttatttttat caaaattttt tatttttaat agcctcttga tatgtctaca acattatcta
    20221 caggtttatt ctccattata tagtgtttca aattattata aaccatatta aatgttctct
    20281 ctttgttttt atctgacacc caagaattat gaggagttac tatgacattt tcgcactccc
    20341 acaacttatt gtccttgttt aaaggttcac tttcaaatac gtctaatgct acccctctaa
    20401 atttctctac acattcttct aaatctttct gattaactgt atttcctcta cctacattta
    20461 taaatacaga accatctttc ataagtttaa acatatcttt gtttactatt ccatctgtac
    20521 tttttgtaga aggcattgct acaactacta tatcacattc ttcaaataca atattcatat
    20581 cttcagtagc aaaacactta tcaaagtatt ttttactact tccatcagta ttgacacccc
    20641 atatttctac accaaaagct tttaatcttt ttgctgcttc tgaagatata gtacctgttc
    20701 ctaaaaatcc aactctttgt ccatacaatt ctgatacaga aaaatccatc ttccattctt
    20761 tattttgttg ttgtttaaaa aattttgcac tatttttata tatttctaaa atatacaata
    20821 caatactttc accaataggt acactatatc cgcctctatt attagctatc ttaatatttc
    20881 tcttcaatac ctcttctttt ggaagttggt ctatacctac actagttgtc tgtatatatt
    20941 gtaaattttt catcttagaa atatctaatc tctcaaatgg attgtatgta actagtacat
    21001 ctgctgtatt tacatcctca ttattttcaa tactatcttc agagtaatgt atgacatcat
    21061 agcctaattc tcttatttta tcaaattttt cttttccata atttattgta aataaaactt
    21121 tcatctcaaa tctcctccat ctacccacat ttaaaatttt atattctaaa atataatatg
    21181 atactcaatg tacattagtt aaaattacta taagatatct taaatttact tatgttcaat
    21241 tgtttttcct aaagacatag cattacgttc ttgaactaaa ttttctatta aattattcaa
    21301 tgtccaatca atagatgtct ctgttaccat agctgtaaaa ggtctattta ttctcacttt
    21361 ttttagccct tctaaaaatg catttacttg tgtgcttgga gtgttattaa atattacaga
    21421 cttactctta atcccatttt cacattcatt tgatatattt ccatctaaaa tgtctcttat
    21481 tatattctct ccatttttat cacttaagat gatatggtct cttattccag caaagttact
    21541 tacgttttta attaatgata attctttttt attaaagttt acaagcataa tacacttcct
    21601 gttgtgtatt ttatctaggt tattattatt tattttttca aatgacattt tatccatcct
    21661 ttcatttatt tatatacttt aatttacccc atacatttaa aataatcaat ttttatagtt
    21721 aatttttata ttaataccca aattatattt aaatagttgg gctatccaaa actaatatat
    21781 aaaattagaa taattagatt aatatctaca aatcataacc taaaggagag ataccatgaa
    21841 tacattacta aacaataaat ttagcattaa aaacttttca aatgcttggg ttatagtact
    21901 tggttgtatg ttgatacaag ctgttccatt tagtattgta gcaagtatac agcctcaatt
    21961 tataagttat gttgtagaag gagaaggctt tagtttagct tctttttctc taatattcac
    22021 tattggtact attgcctcag caattgcatc accttttata ggtgtattat tttctaaagt
    22081 caatattaag atactatatt tattaggttg tataatttct agtattgctt ttgctacttt
    22141 ttctatatgt actgaactat ggcaatttta cactgtatca tgtattgttc aaattggcgc
    22201 tacaattata tctgctatag gaatacctgt tttaataagt gcttggtttg atgaagaaag
    22261 caaaggaaaa gctttgggct ttgcttttgc tggtggttct attggtagta tatttctaca
    22321 accacttgca gttcgcttat tagcaactca aggatacagt cgttcttatc taatatttgg
    22381 aattatagca ttaatagttg gtatacctgt aatattattc atactcagga tgcctaaaga
    22441 tattaatgaa aaggtaaaat ctaaaggtaa aaaagagaaa gcatctgata caatttctcc
    22501 ttcagtatgg ggttatacat taaaagaagc taaaaaaatt aaatattttt ggattatgac
    22561 tattggattt atatttgttg gtatatatgt ttcatcatta tccgtacaat atccaactta
    22621 tcttagaaat tatctaaatc ctattctaat aggaacagta ggctccacat ttgctttatt
    22681 tgctctcatt ggtaatttat ttggaggatt attgtttgat aaattcggtc aaacaaagcc
    22741 acttattata tcttttgtat tggttcttat agcaacttta tcattactat tggtagataa
    22801 atcttctact tttgcatttg tatttgccat tttgaaaggt ctttctgtat ttgcttatat
    22861 gattggtcct gcttatttaa ctggctcttt ctttggtcaa aaggagtttg gtagcatata
    22921 tggaatcgta caattaattt ttgcagtggg atttgcatta ggttcaacat tatttggatt
    22981 gttagttgat aattttggat acagattttc ttggtctatt ataattttat cagttataat
    23041 tgcctatact ttacttatta taacttctat aggaatgaaa aaattgaata aagaaagatt
    23101 agataaacta atgcaataat tgatttttag atatataaat attataataa aaaagatgga
    23161 gcttttaatc ataaataaaa ctccatcttt tttatattac aatatagcta attttctctt
    23221 atttttaact ttactatcta tatcctcatc cttaactata gtaaatgcct tagttggaca
    23281 aacatttaca catgcaggcc cttctggcga ttctatacaa aaatcacact tatttgctgt
    23341 cattctttct ctaaagcaaa gctttccttc atctacatct tttaatgtaa ctatgtctat
    23401 tgcacctata ggacatgcta acatacaagt cttacatcct atacaatttt cttcatttat
    23461 ttttattgtg ttcccaaccc taactatacc accatttgga catgcctttg cacaaggagc
    23521 atcttcacaa tgtctacact gtattggagc acttacttct tttgtcttta tgacagaaag
    23581 ttttggatta aaatttattt catctagatt ttggtaaaaa atatcttcat ctgaatgtgc
    23641 aactacacat cctatcatac aagttctaca tcctatgcat ttatcagggt ctgctataac
    23701 aaaatagttc atcacttagc cacttccttt cctatacaat atgtagtgtg taatagatga
    23761 tgagattttt ctcctaatgg ttctaccaga tattcatcat acagtttttt aatatcagga
    23821 ttctcatgag attttctaat tgctaaatgt tcatcatgca cgtatgttgc ttttgttcta
    23881 ttttcataag ccaattcctt atattcttct agtaaaattt ttggttgacc tccaccactt
    23941 acacacccaa caggacaagt cataacttca ataaaatcta catctaattt tcctttttcc
    24001 aagtcttcaa gcactggtat tacatttttt aatccactta ctactccaac tcttaagtct
    24061 aagtctccta ttttaatagt tgactttcta aaaccatttt ctcctcttac ttgttttact
    24121 tctacatcag gaatactttc tccagttata agctcatatc ctgttcttat agcagcttcc
    24181 ataaccccac cagtaacacc aaagatagtt ccagctccac tataactacc taaaggacta
    24241 tcaaattttt cttctcttaa atttttaaaa tcaattccca tgtcttttat taaataagct
    24301 agttctctag tagttaatac tacatctaca tctctatatc cactagaatc catttcttct
    24361 ctatcacatt catatttttt acatgtacat ggcattatag aaacactaaa tatctttgat
    24421 gcatctacat tatttatctc tgcaccataa gttttaaata ttgcaccacc catctgctga
    24481 ggtgatttac aagaagataa atgattagtt aatttaggat aatttttttc catgaatttt
    24541 acccaagctg gacaacaaga tgtaaacatt ggaagagttc caccttctgt cactctttta
    24601 attaattcac taccttcttc cattatagtt aaatctgctg caaaattagt atcgtagact
    24661 ctatcaaaat ttaaagctct aagtgctgct gccattttcc cagcacctaa gtatcctaaa
    24721 taatatccga aatcttctcc taaagcaact ctaactgctg gtgcacattg gaccatagtg
    24781 aatacatttg ggtcacttaa agctttcttc accttatcta tatcacatac attgtatgct
    24841 gcaaatatag gttcatttat agactctggt atctctcttt cttgtttttt ctcttgtaaa
    24901 aactcaaatc cttcatctat aactgaagca taagatttac aagtttgaac acattgaccg
    24961 cacataacac atctatctaa atttatctct tgtggctttc cctcttcacc ttcaatagca
    25021 tttactggac agacctttga acattctcta catccagtac ataaatcctt atctatattt
    25081 attatcataa acgtcaccta cccctgtatc ctttatttat ttgttaacaa taaactaagt
    25141 gcagcttgtc tattcttagc ttttttgtca tctattggag taacaagttt taatgcttcc
    25201 tgaggacatg cacttataca agctattttt tcattgtctt tacataagtc acatttataa
    25261 gctatcttct tattttcatc taaaattact tgttctactt ctttaccatc ttcatattgt
    25321 ggaagtaagt ctatagctcc aaaaggacat gctagcagac aagttttaca tcctatacac
    25381 ttttcttcat ttacagacat aatattgttt tctttaacta tagctttttg tggacatgag
    25441 tttaaacaag gagcatcttc acactgtcta cactgtattg gcatacagaa attgtcacct
    25501 tttactaagt aaagtctagg tataacaggt atatcaactg ttccaactgt ataacccaca
    25561 ttattatgct gattatgcat tgtaaaacaa gctacttcac aagctctaca acctgtacat
    25621 ttgtttgggt ctgctattac aaaagagcct attttatttt tcatattatc ccacctttca
    25681 atttgtatat ttccaaccct ctagttattt tcatcatatg tctacttact ttcatcatat
    25741 atatttatat atttcactat tttctcagta cttatatttc gtttacattt tttgcacaaa
    25801 ttgtatgtgt tattatacac cttatcagta tcatcaatta atactccaca gatttcacac
    25861 tttgaatatc tttgctcttc ttttttagta cacatatatt cattctcact ttttgataac
    25921 tctctgtgga tttgcataaa tattcatccg tcttcctctt acaaatccaa taagcgttat
    25981 atttaatttt ttagaaagct ctattgataa attagtcggt gctgattttg atactacaat
    26041 aggaatttga gtcatagctg cttttaatat catttccaat gatattcttc cacttacagc
    26101 cacaatttta tcttttaatg ttatgtcatt taaaacacaa aatccaatag ccttatccat
    26161 tgcattatgc cttgctacat cttcacaagt gactattttt ttatcaaaat taaatacaga
    26221 tacgctatgt accccaccag tatttttaaa taattctgat gaatttaaat ttctatccat
    26281 tatactgtaa atcgtatcat aatttatttt tatattgctc tttacaggag cacatgttat
    26341 atagtctagt gaatttaaaa atataatttg ctcatcttga tttttttgtt tctcttgaat
    26401 agttactttt gcaaaacgtt cactctcatt tatctcaaat tttaataagc tttttttgtt
    26461 ttctatgtat ccttttgttt tcaagaatcc tactataagt tcctctaaat tatatggggt
    26521 acataaaaat gtatttatat atttatcatt taaaataaaa ctaagtggat attctgcaat
    26581 tatttcttca ttatctattg atacttcatg ttcatttatt ttgcttactt ctacattaaa
    26641 agaatttaaa tatttgtagt ccactagact ataactattt tcaaaaactt tatccttact
    26701 attttcttgt aatttagttt ttgagtatat attgttcata aaatattagc ctttctgcct
    26761 tttataaatc ttaaatctaa taaatcatta gatatttgta gctgtcattt tgtctttcaa
    26821 actttgatac tcttctctta cacatttttc tgctaattct tggtcttcaa gtttttcaag
    26881 tttaacagca caatatttat actctggtgt tttagatata ggatctaaat ttgctattgt
    26941 aagttcattg caagctccaa cccaccactg ataagtcata tatgttgcac cttccttaac
    27001 tctatcagta actgttgctc ttgttattac acttcctctt cttgaactaa ttctaactaa
    27061 ttcatcatct tcaattccta atttttcagc atcattagaa tttatttgaa cacgtcctgg
    27121 ttcatcttct aatgaactaa gtgttctaca attaccagtc attgttctta ctgaatagtg
    27181 tccaacttct cttacagtac ataaactaaa tgggtattca tcatcttcaa cttccatagg
    27241 gggtctccat tcagcagcga acaaattacc tttaccatta ggagtagaaa acttttgacc
    27301 ttcatacaga tacatagttc ctttatcttc catactttca ctcttacaag gccattgaac
    27361 gcatccttga gtttctatct tttcataagt agcacctaag aaacttggac ataattgtct
    27421 aagttcgtcc catatttcct tagtattttt ataattcata ggatatccca ttgctgtaga
    27481 aatttcgctt ataatttgcc agtctggttt tacatctcct tgtggctcta tagcttttct
    27541 catcaattgg aatcctctat ctgcacatgt atatactccc tcatgttctc cccaagaagt
    27601 agctggaagt ataacatcag cgtgaagtgc tgtcttattc ataaatatat cttgaacaat
    27661 gacaaattcc aattcatcta atgcttctct aacttctgat gcatctgggt cactttgcac
    27721 tgggtcttct ccaaatatat aataagcttt aagctttttc tcttttagta ctaaatttgg
    27781 aacttgagtt aaactataac cattattagg agataatttt accccccaag ctttttcaaa
    27841 cttttctctt atcttatcat cagttacatt ttgatagcca ggatatacat taggaagagc
    27901 tcccatatca caagctcctt gaacattatt ttgtccacgt acaggtccta ttccaacgct
    27961 ttctctacca aaattacctg taagtagagc aattgatgca agtcccttaa ctacatcaac
    28021 agcttgacca aattgacaga cacccattcc ataaagtatc atagcttttt taccttttgc
    28081 atattctctc atagcttttc ttataagctc ttctgggatt cctgtaatct tttcagcata
    28141 tttagctgta tatggtttaa caatttcttt atactcatca aatccttgtg tatgattttg
    28201 aacaaattct ttattgtaaa gaccttcttc tattaataca tttccaaaag catttactaa
    28261 aaccatgttt gttccacctt ttataggtag atgtatatca gcaattcttg cagattcagt
    28321 tactctaggg tcagtaacaa ttaatttagc accatttttt ttagctttta ctattctatt
    28381 tgccactatt ggatgtgaat ctgctccatt atatccaaat ataaataaaa catctgcatt
    28441 ttctatctct ggtatagaat tagacattgc accactacct aatgagtaag ccagaccggc
    28501 tacagatggt gcatgtcaga cacgagcaca atggtcaaca ttattagttc ctattgtagc
    28561 tctcataaat ttttgcatta tatagtttgc ttcattacca ggtcctcttg cagaacctgt
    28621 tcccataata gaatcaggac catatttttc tttaatttca tttagtcttg aagctgtata
    28681 gtttatagcc tcatcccatt caacctcttc tagtacacct tgttttctta tcattggctt
    28741 ttttagccta ggtgttagaa ttttagggtc atttagaaaa tcccatccat aacgaccttt
    28801 taaacacaaa ctttcttgat ttgttctacc attagccggt tcagctctta atatcttatt
    28861 atcttttact actagatata attggcatcc agctccacag tatggacaaa ctgttaaaat
    28921 ttttttctcc atacaattcc ccccttagat ttatcccctg ataagtaaaa tttatcttaa
    28981 agataatgag tgtttttata atatgcaaaa tcataaatat tttgcaatac tatctattaa
    29041 attcaacaat tttctcacaa ttcctcttaa atttcaaaaa aaatatgtca taataatctt
    29101 tatatttcaa ccatttaatt aaaatattct agttcttatg acatattttt taatatactc
    29161 aatatatatt ctttaaactt atttagtttt cacttaaaac aatatttctg ccaattctat
    29221 ttttcattct atagtgagta attacagtaa atattccact tccaatcaga atcaaatagt
    29281 acataaatcc accatataaa aatactgcat atcccatcaa aggttgaggg aatactgatt
    29341 tgaatatagt gaaaaaggct aattcattag ctcctacatt cccaggtgtt ggtattggag
    29401 atattgccat atataaaaat gcttgtaatg tcagtatata aatatagcta taaccttgta
    29461 aattaaatgc tttatatatc caaaatgaaa cactaaagta agcacttaat tgaataaaag
    29521 ttactattat agttgaaatt aatacctttt tattctttgc aaaaaaattt attgctttac
    29581 tataatcatc tataaaactt tctatggatt caatcttatt atctaaaaat tttaaaaact
    29641 taatttttga taaatgcttt atagtaattc tcataaaata ttttattttt ttaggattta
    29701 aaataactaa tattatcata attaagacaa atgaattaat ggctatccct agaaacacta
    29761 gaggcataat cattttcatt tgtttttcta acatagcaaa attcattaaa acaagtattg
    29821 tacaataaaa agtaactact atttggaaga taatagactt attggtaaca actgcacttg
    29881 ccttactaag tggcatttta cattttttaa gtacatatat ctgtactggt tggcttcctg
    29941 aagcaaaagg agttattaaa ttataataaa atcccataat ggctagctta aaaccaataa
    30001 atctaatatt aactttgtga gtgctttcta taattatctt cattactact ccttcaagca
    30061 ttatgtgaca cattattgcc aaagcaccta tgaataaaaa cttcttatct accataacca
    30121 taacatttga tagcatttta atatccaatg ttttaaacac taggtaaatt gttataccta
    30181 ttaacaaaaa taaaaatgta tactgtagta aactctttct aatattcttt agtctatcca
    30241 ttagaaataa ccatcctttg ctcaagattt atactaaata ctatattatt agtatacact
    30301 atgaatctta atattttata acaaaatacc ttacaatttt gtcatttaca aaaaatatta
    30361 atctataaat taaattttaa tatatagatt aatattttac aaacatt
//
LOCUS       DAEPHU010000053        29862 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 01A10CD0081
            SAMN05941466-rid12468953.denovo.053, whole genome shotgun sequence.
ACCESSION   DAEPHU010000053 DAEPHU010000000
VERSION     DAEPHU010000053.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941466
            Sequence Read Archive: SRR6291087
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 29862)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 29862)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068158.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 22:43:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,892
            CDSs (total)                      :: 3,805
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 87
            rRNAs                             :: 8, 1, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 55
            CDSs (without protein)            :: 55
            Pseudo Genes (ambiguous residues) :: 0 of 55
            Pseudo Genes (frameshifted)       :: 21 of 55
            Pseudo Genes (incomplete)         :: 28 of 55
            Pseudo Genes (internal stop)      :: 16 of 55
            Pseudo Genes (multiple problems)  :: 8 of 55
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..29862
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941466-rid12468953.denovo.053"
                     /strain="01A10CD0081"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            complement(629..1138)
                     /locus_tag="KR231_002436"
     CDS             complement(629..1138)
                     /locus_tag="KR231_002436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CarD family transcriptional regulator"
                     /protein_id="HBH0004803.1"
                     /translation="MVMFLFKIDDYIMYGMTGVCKVMDITNERFTNGIKKEYYVLSPI
                     YSNNTVIKIPVDNEKVPMRKLLSKINVLSLINDIPNMDTSWIDNEKLRSEQFKKILRG
                     GKCEELIKLVRSIDNNREYVKSIGKKTHQADDNIMKEAERLLNEEFATILDISPNEVS
                     SYISSHIPQ"
     gene            complement(1349..2758)
                     /locus_tag="KR231_002437"
     CDS             complement(1349..2758)
                     /locus_tag="KR231_002437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0004804.1"
                     /translation="MENYFDKQAKELYNKASEIINTHSMLKANRANEKFDIDIPQDFK
                     YEFFSLVDKVNLSLMEEEDNFYGYFLFQMSREIRFDISSPTGVNFKGAKYVIYFNPII
                     FLTLDIKQMETTIKHEIHHILSMHLMRAKELKGKYSTLAINMAMDIVVNKFLNNLPPY
                     ATTLEWVNLKYSLKLEPYEPFEYYVEKIQTELDLMEVDEDGEEDDSDKYGDIEIDYSP
                     ERTHDIWDESNEIDENTLREFTEKFINSSQKGKVPAYLESMISSLKNSKGELPWNLYL
                     NRIMGTVENNKKKTITRRNRRQPNRLDLRGELRSHKSEIAVALDVSGSISDEEFKQAI
                     KEVLSIVKNYNHEITIIECDNEIRRVYKVRTEKDIKDRIRIGGGTRFSPVFEYANNKK
                     INLLVYFTDGKGENKLQVIPRGYKILWVISGRGDKISLKEPYGAVKKLTKVKTNDEIL
                     EINDVRNDGYSMNSQAPIL"
     gene            complement(2762..3892)
                     /locus_tag="KR231_002438"
     CDS             complement(2762..3892)
                     /locus_tag="KR231_002438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HBH0004805.1"
                     /translation="MNFIDTLKSVDLILSTGEVPLIVGESGIGKTALANKLAKENDWS
                     LIVIDGNLLKEGEIGGLPTIESYVGVNSNGYKTEKKTTVYAVHNKLREIDEEISKSKT
                     VLLFIDEINRCEHTVQQELMNLILNREINGYKLHDDVKILAAMNPSSKYGSDFDYQVV
                     DMDAAQENRFVWLNMESDHTQWIKWAIDEGIERKVIEFISTFPEYLHKINEDDVRATP
                     RSYERVSKIYKVYKEKNNSIPRAVFLNVVKGNVGKVIAEEFISFIESNSEPLISYEDV
                     FLGESIDESIVERVKNESHTRLYLSAMNILKDLELNIKNDKYESNHYINRFIEFLKMY
                     PVDLMIGIMKDIRNSYIEVYKKAIENEEFVKSYFESYSLIRG"
     gene            complement(3904..4707)
                     /locus_tag="KR231_002439"
     CDS             complement(3904..4707)
                     /locus_tag="KR231_002439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0004806.1"
                     /translation="MEKLRVIEMIKNNPNIIATIDNPTDEMKLLAIKENGLVLEYINN
                     PTREMQELAIDNNIRAIKFIDNPTEDMMIKAVNEGWSILDYIKNPTDKVIEMAINQAG
                     WAIKYAKNPSEELQLLAVRKNYDSIKFIKQPYESVQEEAVRISYDALRYIDSPSYNAE
                     LIAIKNNEAAISFITDLDKNKMLEFLKVNILVIKYILKKVSKDELESVLKEVLSKEDV
                     EEKYIRDFLNCSVIDRNSESIPIDKIMFIYKYGSKTAKKIAVDEKLKIM"
     gene            complement(5089..5970)
                     /locus_tag="KR231_002440"
     CDS             complement(5089..5970)
                     /locus_tag="KR231_002440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proline iminopeptidase-family hydrolase"
                     /protein_id="HBH0004807.1"
                     /translation="MKITEGYMPFKGFKTYYRIVGENTEGKKPLVLLHGGPGSTHNYF
                     EVLDKIAESGRQVIMYDQIGCGNSFVEGHPELFNADTWIEELIELRKHLGLDEIHLLG
                     QSWGGMQAIWYAIEYKPKGIKSYILSSTLSSAKLWEKEQKRRISYMSEVDQKALLDAV
                     NTGDYSSKEYNDALERFMEMYCAGEVTEDSPECLRRPKKSGSEAYIVGWGQNEFSPTG
                     TLSGYEFTDRLHEIKEPCLVTSGAIDLCSPYIAKTMYDRIPNSKWELFEYSRHMPFVE
                     ENEKYIKVLTEWLNAND"
     gene            6426..7400
                     /locus_tag="KR231_002441"
     CDS             6426..7400
                     /locus_tag="KR231_002441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0004808.1"
                     /translation="MNNINSLKVIKLSLGCSLAIFIAWLLKLEYSMVAGVIVLLTVKD
                     TKRETLKGSIGKIYGFLLCTIFSYLCFNILGYNLTSFSIFIFIIIPLCFLLNIQDVIA
                     MCVVIASHYYLQGETSIKWILNEAGIFAVGTGIGVLINMYIPTNIHKIHEVQKKLQEE
                     VSIVLIDIADIIVNPKKENGYSRDLYTLNSLIDSSISETYDNINNTLLSDTRFFLEHM
                     DIIKSQRDILENLYSYVSQLNSTPPQAHILSAFIHKIGYTEFEAETGNLLLEELKRLM
                     LSMKNQPLPVDRTEFENRAILFLCLTELKQFLVNRKHAQILRDNNFYK"
     gene            complement(7516..8577)
                     /locus_tag="KR231_002442"
     CDS             complement(7516..8577)
                     /locus_tag="KR231_002442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transglutaminase domain-containing protein"
                     /protein_id="HBH0004809.1"
                     /translation="MKKIRKLTTKLLITTIVLISGMSMTVYGMTAKEVTAKTPKSYVT
                     GTNSVYGPKLSQAQLNSVAQATADFMNKKITKNMTTDAKILVAYNHIKNNTTYVDWNA
                     VEGANTAYTLVTKKGACSGMARSMKALCDAMGIESYYVHSTSNDHQWNLIRFGDGRLY
                     HVDIDANKSAGKDIIYKSLSHPLPFDKTAYPKVGAIVQTVKPEQTQKPAPPGKHTMLP
                     HQEGAKAVGNFGKKGEDINEKHVMYEGVRCSVVNSSVNTITFTGSESNLDPSNLTIAV
                     IGFMNTPYGMFALAPEGKPVEYPFKYDKPFSLDFSGKNRSGAELAKYCKKNDVTIKIE
                     ITDEKANIGLGQIMYVRYE"
     gene            complement(9189..10040)
                     /locus_tag="KR231_002443"
     CDS             complement(9189..10040)
                     /locus_tag="KR231_002443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HBH0004810.1"
                     /translation="MSCILKLKQIYEDLTEVDKKIADYILNNTEAISKLSVSELASNS
                     KTSTASIVRFSRKMGYSGFGDLKIEIAKDLMGKENEYTYVDENYDCNIDSVINKITNK
                     NIETINQTRLLNEKDIIKEAVEQIIKAKNVYIFGVGGSALVALDLQMKLLRINKQAFT
                     SLDSHTQLMVSSNVDKEDIAIAISYSGESKEVIKSIENAKLKGCKVICITKYSDNHLS
                     KISDLKLVVPNIEKRLREGAISSRIAMLTLIDIIYISIIQENLNEAEQKLQETKRILD
                     YLNINNA"
     gene            complement(10057..10977)
                     /locus_tag="KR231_002444"
     CDS             complement(10057..10977)
                     /locus_tag="KR231_002444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA reductase"
                     /protein_id="HBH0004811.1"
                     /translation="MYFLGVDGGGTKTTFTLVDEELNIVGTITKGTCHYNQIGFDNLT
                     KLLITGLEEVCKDAKINVEEITYAFVGLAGYGKIKEVLYALEVATKNAYSHINYTLGN
                     DVEIALAGSLNGEKGINIIAGTGSIAQALDKDGNLHRCGGWGYVLGDEGSAYYIGMAT
                     LKMFTMQSDGRCSKTKLYDLIKRHLNIENDYDIIKYVNDEIQGDRIEIAKFATICLKA
                     VIEGDNTASKIFDDAAYELSRLIIGLEHHFEQGTKIKVSYSGGVFKSGDLILEPLKKY
                     LNKTRFGIVRPVLTPDLGACLLAKKKYYSK"
     gene            complement(11087..12001)
                     /gene="murQ"
                     /locus_tag="KR231_002445"
     CDS             complement(11087..12001)
                     /gene="murQ"
                     /locus_tag="KR231_002445"
                     /EC_number="4.2.1.126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramic acid 6-phosphate etherase"
                     /protein_id="HBH0004812.1"
                     /translation="MLIKTLENLVTEGRNKNTLQIDKEDTLGIIELINNEDKTVAYAV
                     EEQKESIAKAVNIIVDRMKQGGRLFYIGAGTSGRIGILDATECPPTYGVDFELVQAII
                     AGGNQAIFKAIEGAEDDKELGKQDIIDRGVTSKDVICGIAASGRTPYVIGAMEYAKEL
                     GCAVLSITMNPNSEMSKKADLPINIIVGAEVIMGSTRMKSGTAQKMVCNMLTTASMVK
                     MGKVYSNLMVDVKTSNEKLVERAKRIIMIATNVKYDVAEKFLEEADNSVKLAIFMIKS
                     GLDKDSAKSILDRQEGYISEALKSIEKL"
     gene            complement(12100..13197)
                     /locus_tag="KR231_002446"
     CDS             complement(12100..13197)
                     /locus_tag="KR231_002446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF871 domain-containing protein"
                     /protein_id="HBH0004813.1"
                     /translation="MGRLGISIYPEKTTSKEIYDYIDKAAENGFTRIFSCLLSVKDTK
                     ENIIKKFKRINEYAKFKGFEVILDVNPRVFGELEISYKDLTFFKKTKADGIRLDIGFT
                     GSEEALMTFNPQNLKIEINMSNNTNYIDTIMDYQPNKENLTGCHNFYPHRYSGLNLEH
                     FIKCTERFNKYGLRTAVFVTSQNETTFGPWPVTDGLPTIEMHRNLPIDIQVKHIIAMN
                     NINDIIISNCYPTYEELKVLGSMRKDMVTFDVAIEENIREVEKKILFEEIHFNRGDIS
                     DSLIRSTQSRVKYKGYKFELFNTPKIIKRGDIVIESSEYGHYAGELQIALTDMKNSGK
                     SNVVGYIRKEELFILDYIKPWQKFNFKPSTK"
     gene            complement(13430..14776)
                     /locus_tag="KR231_002447"
     CDS             complement(13430..14776)
                     /locus_tag="KR231_002447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBH0004814.1"
                     /translation="MLDKFTEFLDTKLSTSMARLAEQRHLRAVRDGIVASLPLIIVGS
                     FFLILAFPPLPDSWGVTQYLKENAVTILLPYRMTFFIISVYSTFGIGYSLAKSYKLDG
                     LTGGLLATATFLLTIVPTAIEGLTPELLKIVEKSPELLAWYNSIPQGWQMPMANLGGG
                     SMFVAIVTSIIGVEIYRFTDKSKFKITMPEAVPASVTRSFEALTPAALIIILMAIVTY
                     FLGFDWHGFIAKLVTPLVSATDTLPSVIILIFLITFFWSFGIHGVSIIGSLARPLWIQ
                     LLDANTASYAAGQAVPGIAAEPFFQWFIWIGGSGATIGLALLLAFRAKSAYGKSLGKA
                     TVIPAIFNINEPIIFGAPIVLNPILIIPFVVAPIVMATVSWFAMSANLVSRVVVTAPW
                     TLPGPVGAYLATGGDWRASVLNLLCIAISIIIYYPFVKMYDKRLLHEEKVEEQEAY"
     gene            complement(14865..15173)
                     /locus_tag="KR231_002448"
     CDS             complement(14865..15173)
                     /locus_tag="KR231_002448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBH0004815.1"
                     /translation="MRVLFVCSSGMSSAIAVNALQKEGAKNGIDIDVLAVGTQEFENE
                     VKNGWDIAMVAPQVRHRFDYLKAFADEVSVPCALIQAQAYSPLGGPKLLKQVQELLSK
                     "
     gene            complement(15435..15833)
                     /locus_tag="KR231_002449"
     CDS             complement(15435..15833)
                     /locus_tag="KR231_002449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0004816.1"
                     /translation="MSNNKKKKRKKNNNYKNAKSTKSNKNTKKQMEKNQRTDYNIPTI
                     SFKSGLILIVSSLVSTVVFPLLLSIFGIDNRFGVVIGNSLITSFAVAYTRYFVETKRG
                     FSLGFFRLYILFALSFAIIGYFWIYKGIHI"
     gene            complement(15835..16995)
                     /locus_tag="KR231_002450"
     CDS             complement(15835..16995)
                     /locus_tag="KR231_002450"
                     /EC_number="2.7.1.170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anhydro-N-acetylmuramic acid kinase"
                     /protein_id="HBH0004817.1"
                     /translation="MITMYSVGLMSGTSLDGVDAVLAEISGNGRNTKVKQIEFITLEI
                     PKDIKDEIRKCCIEEESSVDLICSLNFKLGYLFSKAVKSVCHKANFHIANLDFIASHG
                     QTIFHIPRSYNNFVSSTLQIGEPAVIAYETNTKVISNFRVMDIAAGGEGAPLVPYSEF
                     LLYSDNNKNLALQNIGGIGNITIIPKSCNIDDVFAFDTGPGNMIIDGVCQRLFNRKYD
                     KNGYFASKGKINEEMLKDLMSHKYLSQAPPKSTGREVFGQVYLDNMLNKYKHVDKYDL
                     IATVTMFTAKAIYYNYKNFILPKVNVDTLLIGGGGAHNLTLIGYIKELLLEVEVLTQD
                     EYGYSSDAKEALAFVILGNETLNNSFSNVISATGAKNKVILGNITPKPFGGK"
     gene            complement(17426..18445)
                     /locus_tag="KR231_002451"
     CDS             complement(17426..18445)
                     /locus_tag="KR231_002451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBH0004818.1"
                     /translation="MLVKYLKGRSKYIALPLVVVSIINIYLFAIDIFKNKYSELIYLD
                     FLVLFIIMVFFVIDYINFRNSYTNLYNCIENSGEIDSYLVDGQSFEENLIKDIIENLK
                     IKNNSDIETYKQSLKELDEYIAKWVHEIKIPISSLSIITDRLSSIEDSLDIKNQVAKI
                     NFLVNSILYSSRSNTMFEDVFINKFNLEKLVKMSIKNNSFLLIKNNVEVSLNELENDV
                     YTDSKCMSYVLDQIINNAIKYSKEVGKIEFNSKKLENGVVLSIKDFGIGINEEDISRV
                     FDKGFTGKNGRNQLYKSTGMGMYFVKKMIDSLGHEIEVCSKIGSYTIFNIYFYDISDY
                     LSIDS"
     gene            complement(18439..19119)
                     /locus_tag="KR231_002452"
     CDS             complement(18439..19119)
                     /locus_tag="KR231_002452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898117.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBH0004819.1"
                     /translation="MYRILLVEDDIDLSKEIALALEKWGFKVELIDDFEVVLDEFIDK
                     KPDVVLLDVNLPLYNGFYWCEKIRAISNVPLIFLSSRDSDMDLIMGINNGADDYITKP
                     FSIEILVTKINGIIRRVYNYSDSNSILYCEDLMFDVGKGIIKHKYKDKSIELTKNEIK
                     ILTLLLKNKNRVVSRESLMMTLWDNDEFVTDNALTVNMNRLRSKVKELGFDDFIKTKK
                     GIGYIIQC"
     gene            complement(19271..21178)
                     /locus_tag="KR231_002453"
     CDS             complement(19271..21178)
                     /locus_tag="KR231_002453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HBH0004820.1"
                     /translation="MSILGIAYNNFKSNIRTYLAFFISMVFSVVVLTNFELLRYGDAI
                     NVLQEENKKFTLSVLVAVIMILSVFLFFFIWYATNIFFKNRSKEIGILSFMGLDLYTI
                     GKIYFVENMLIGISSCITGIIIGIITSRFFQVVIIKLSGFNIKVSNGLSIEAILYATL
                     IFISIFIIMAVKGFITICRSSVINLINISKKQEKIPKVGIGIYILAIVSIIVIGYGYY
                     LSTNIRTGDITSVLPVIGIIIVGTYGLFKSVMPVIFDIIIKNKKILFNGNNIIAINNI
                     NYRLNKNYKTYAIIAIIITTTISTLGASVAMKHIHKNAQEQRNVYTISIVSMDKDEVN
                     KKQIENIIKDTNKIKYSVNPELTILKKTDIKEAYDTTDTIMKYSDFCNTLKVNGNDKE
                     LKEYGERLVSGNNVIELKSPQTIASIATKEAKIKLDGQLYNISRGEVKVPVLGTGLNQ
                     SIIVVNDDTYFKLRDKGQQVYFYGAKVFQEENSQVMFNNIEKNLSLKNGYIQNGYKAQ
                     GESQWMKFAYVVLVFLFLVFAIVAGSIIYMKIYSDAYEDKEKYKILLKIGTTEKDINR
                     AILKEVAIFYTLPMLSATISSYFALRLAGDLLMTDLFGIYILSLVICLIIFIIYGAVS
                     VNKFKSVVYKN"
     gene            complement(21179..21931)
                     /locus_tag="KR231_002454"
     CDS             complement(21179..21931)
                     /locus_tag="KR231_002454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH0004821.1"
                     /translation="MKEILKIKNISKDYGIKGFKTNVLKNISLTVNEGDFISIMGPSG
                     AGKTTLLNLMSTLDKQTSGEIILDGINISKVKNNELSKLRREKIGFIFQDYNLLDNMK
                     LMDNIALPLALGKKKSKEIEAKVFSIAKKFGLENHLDKYPYQLSGGQKQRGAAARSLI
                     TNPTVIFADEPTGALDSKSAYELLESLEKINRENNATIIMITHDPLTASYSNEVYMIN
                     DGNIKCKLNKGNSRKEFYGKIMDMLASMGGEM"
     gene            complement(22247..23401)
                     /locus_tag="KR231_002455"
     CDS             complement(22247..23401)
                     /locus_tag="KR231_002455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427194.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBH0004822.1"
                     /translation="MINKAIKFKFIIFYFFSYIIFAFASTKFTPFLSKLGYSAFERGI
                     ILSSYAITNILFQLLFGVLADKYQTMKKIVLISLSVYGIASVIMFSTESATFIIYLLL
                     VALSGGLLNTCCSLYDTWIIGCGDNINNYLSFIKTFGSIGWAIGSMVASYLILRFSYF
                     GLSVAIGLIVVLLIINILLLPDIEKINKKINVTNKDIIELLKDKKYILLVCILFLLYS
                     MVVANNCTVIDKMIALNATNSQISLKWSLQSLLEIPTYLAGSYLLKKYSSLNLLKLSA
                     IMITVQFLLFALTNDSNIIIILCVFQVFSTPLILITSKRLIFEVSPKKLRSSSQLIAL
                     SIFMGGSSLIIPTVAGFLSINIGYNYTLMVLSLFGCLAYCLIVLLNYLQE"
     gene            complement(23404..23871)
                     /locus_tag="KR231_002456"
     CDS             complement(23404..23871)
                     /locus_tag="KR231_002456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HBH0004823.1"
                     /translation="MFFKRKKEAITINSYIDGKIINLGEIPDKVFSTKVMGDGFAMIA
                     KDNILKSPTKGVISFIAQTNHAIGIKLQNDVQILIHIGLDSATTKKENFKLEVKQGQE
                     VNMGEKLVEIDNKLLENTLYIPLVIVENPNTVKYHLSNLNQEGNSGIKVINFD"
     gene            complement(23885..24373)
                     /locus_tag="KR231_002457"
     CDS             complement(23885..24373)
                     /locus_tag="KR231_002457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0004824.1"
                     /translation="MITNKIKNITAVLKDENIFLSVVMVCFLILPVLYIVYLELTSLF
                     TNISFSQLLNNDVNASLNLISNFSAVYSAYVIYNIKKNKEIKENMIAFYLVLLGQIFQ
                     IYTITIVIMFTYIYKFVGIKQIISSIKELQWGKSYKALFSSIAVCLISLFVMIIRIKL
                     IM"
     gene            complement(24387..25718)
                     /locus_tag="KR231_002458"
     CDS             complement(24387..25718)
                     /locus_tag="KR231_002458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-alpha-glucosidase"
                     /protein_id="HBH0004825.1"
                     /translation="MERKRQRILIAGGGSTYTAGIVTMLIESVAKFPIESIKLYDNND
                     ERQRKVAEACAIIVREKNPEIKFSYTTNPEEAFTDIDFVMAQIRVGLYALREQDEKIP
                     LKYGVVGQETCGAGGIAYGLRTIGPIIEMIDYMEKYSPNAWMLNYSNPAAIVAEACRV
                     LRPNSRIINICDMPVCLEEIFARVLGLNSRKDFDVRYYGLNHFGWWTSIKDKEGNDLM
                     PKLQEYCAKKGYEEFTPQGQHKESSWLETMRAAKDLLEIEPTTLPNTYLKYYLMADET
                     VEHANPNYTRANEIMDRREKDTFEECERIIKNGTARDTWFDASEHSQFIVELACALAF
                     NTQERFLLIVPNNGAIENFADDAMVEIPCLVGKDMVEPMSIGKIPTFQKGLMEQQVAS
                     EKLAVEAWIEKSYQKLWQSFTMSKTVPSAKVAKEILDEMIVANKDFWPTFK"
     gene            complement(25732..27297)
                     /locus_tag="KR231_002459"
     CDS             complement(25732..27297)
                     /locus_tag="KR231_002459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003233606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HBH0004826.1"
                     /translation="MMKKIQRFGGAMFTPTLLFAFAGIMVGFSIVFQNQSIMGSLATP
                     ENIWYQFWGVISSGAWMVFNQLPLLFAISLPIALAKKQQARACMEALATYLTFNYFVG
                     SMLSFWGKSFGVDFAAEISAGSGLVSIAGIKTLDTGMVGALLISGIVIYIHNRFYDKE
                     LPDFIGLFRGSSLVVAICFFVMIPVALLTCFIWPHIQNVIRHLQTFFINSGNIGVWCY
                     AFLQKILIPTGLHHFVYAPICYDSVVVPGGTSVYWATHIQDFQTSAKTLKEMYPIGFS
                     LSGLSKVFGSLGVFGAFYVTAKPEKKKKVLGLMIPATLTAVLTGITEPLEFTFLFVAP
                     LLFLVHAFLDACLQTISFALGVVGDFGGGIINWVVLNWLPLGMYHWKVYVVQVVVGII
                     FSFIWFFVFTFLIKKFDMKTPGREEDSEETKLYTKNEYLETKDEKGNKLSKASQQASE
                     YIKLVGGAENVVDVTNCATRLRLTLKDDSIISKEEDFKAVGAHGLVHNGKAIQIIIGL
                     SVPSVREEFENLL"
     gene            complement(27467..28252)
                     /locus_tag="KR231_002460"
     CDS             complement(27467..28252)
                     /locus_tag="KR231_002460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HBH0004827.1"
                     /translation="MRLEEMIFLNYNKLNDTDLLIWKYITANKKHCSKMSINELAMKC
                     NVSRATITRFVKKLDLKGFSEFKVLLSWESEKVHVIENQSFDIACNSIIKYVEDQKNK
                     DYDALCKLLYESRTIYAYGSGDIQNVVAKQIKRMFLSCQEIIYDFEGRTFDDSFYNIV
                     SKNDVMIIISLSGENENTLNIARRLKLIGTKIISITEFKNNTLTDLSDESIYISATNI
                     SFLQMHPSYKLTMLYFILIELLFIKYSIYKRHRMITEGIDCKL"
     gene            complement(28419..29618)
                     /locus_tag="KR231_002461"
     CDS             complement(28419..29618)
                     /locus_tag="KR231_002461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase S41"
                     /protein_id="HBH0004828.1"
                     /translation="MKKKVLFLVIILAFIILLGNSTYSQKNQLSEEEKVDDFNYVYNV
                     VKTGYPYLGVNKRLNNIDWLANKDEYTKRIKNTENDEEFIEEMSSILSDLNNKHTEVI
                     DNKKRYELFKKSYSNNDWYDFLNDKKVVDRYDSMNLKIKMPDDIFVKKELILKDVIKG
                     QIGYMYLPSMSSKNGSINNDLKIIGDYIDTLEKHKALIIDIRGNLGGSDSYWQGIVSK
                     LIKNDVKINGYRIYRNNNEIVKQYTNARNIKLNPVENLPTSVKENAPKEIIKDFNDFE
                     DTSYTIKSTDDSKFKGNIYLLVDRKIYSSSESFAMFCKETKFATLVGETTGGDGGCID
                     PVLFNLKNSGLIVRMASCMYLNKNGICDEEFKTIPEFKVKDCKRTADFKDDNCIRKAL
                     ELENINY"
BASE COUNT         9904 a         5163 c         3010 g        11785 t
ORIGIN      
        1 tttcactaaa aaataacaat ctattcaaag ataaactata gtacttcttc tactttgttt
       61 caataaaata ctaaataaat ttcgtacatc cacaattttt caggctacac tataaatata
      121 caatctttat cttagttata agtttaagaa tatttttagt cttattttgt cgaatatctt
      181 tttaataaaa cttcataatt ctaagcatat ttttacactg tgttttcatg tacaaaaata
      241 atgcttacaa ataaacaaca taaataaaac ttaaataaga tggattctat tcaacatagt
      301 atccatctta ttcattcaaa acctaaaagg attttttata atattatata ttttaaaatc
      361 taagtaactc attatagtat caatttcact taaagcttac aatacactta ttaatcttgt
      421 tttatattaa aaacatctac aataacaatt taaatcttta agtgatatcc atctcacacc
      481 taaaggagta ggctctccgc actattctgt aattcttcaa tacaatcatc attatttttt
      541 atataattta attatatatt ttattttacc aaaaccagca tacataaata atacttaaaa
      601 tagattaaat aaaggatact aaaacacttt attgaggtat atgacttgaa atatatgaac
      661 taacttcatt aggagaaata tctaaaatag ttgcaaattc ttcatttaat aacctttcag
      721 cttctttcat tatattatca tctgcttgat gtgttttttt accaatagat tttacatact
      781 ctctgttatt atctatactt cttactaatt ttattaactc ttcacattta ccacctctga
      841 gtattttttt aaattgctca cttctcaatt tttcattatc tatccatgat gtatccatat
      901 taggaatatc atttattaat gaaagcacat taattttaga aagtaacttt ctcattggta
      961 ctttttcatt atctacagga atttttatta ctgtattatt agaataaata ggactcaata
     1021 cataatactc tttttttatt ccatttgtaa atcgttcatt tgttatatcc atgactttgc
     1081 agactcctgt cataccatac attatataat catcaatctt aaacaaaaac atcaccatcc
     1141 ttaataaaaa aaatagtttt gacaactaaa tccaccttgc caaaactatc tgctatatat
     1201 tatattttaa cacattttaa gacttaaatg taagtaaaac ttatattatt aaaattaaaa
     1261 aatacattaa ccattgatta atgtattttt tagattttta taacaagcat atcaaaataa
     1321 attaatacag cttatctcct gtgaatacct ataaaattgg tgcttggcta ttcattgagt
     1381 acccatcatt tcttacatca tttatttcta atatttcatc atttgtttta accttagtaa
     1441 gttttttaac tgctccataa ggttctttta atgaaatttt atctcctctt ccagaaataa
     1501 cccataaaat tttataccct ctaggtatta cttgtagttt attttcacct ttaccatcag
     1561 taaagtagac taacaaatta atctttttat tattagcata ctcaaagact ggagaaaatc
     1621 tagtacctcc acctatccta attctatctt ttatatcttt ttcagttctc actttatata
     1681 cacgtctaat ttcattatca cattctataa ttgtaatttc atgattatag tttttcacta
     1741 tactaagaac ttctttaata gcttgtttaa actcttcatc actaatactt ccacttacat
     1801 caagtgcaac tgctatttct gacttatgac ttctaagttc tcccctcaaa tctaaacgat
     1861 ttggttgtct tctatttctt cttgttatag tcttcttttt attattttca actgttccca
     1921 ttattctatt aagatataaa ttccatggca attcaccctt actattttta agtgatgata
     1981 tcatactttc taaataagca ggaactttac ctttttgaga actgttaata aatttttcag
     2041 taaattctct aagggtattt tcatctatct cattggattc atcccatata tcatgagttc
     2101 tttcggggct ataatcaatt tctatatctc catatttatc actatcatct tcctcaccat
     2161 cttcatccac ttccatcaaa tctaattcag tctgaatctt ttctacataa tattcaaaag
     2221 gttcatatgg ttcaagtttt aaggaatact ttaaatttac ccactctaag gtagttgcat
     2281 atggtggtaa attgtttaga aatttattta ctactatatc cattgccata ttaattgcta
     2341 atgtactata ctttcctttt aactcctttg ctctcatcaa atgcatagat aatatatgat
     2401 gaatttcatg tttaattgta gtctccattt gctttatgtc aagcgttaaa aagattattg
     2461 gattaaaata tataacatat ttagctccct taaaattcac acctgtagga ctacttatat
     2521 caaatcttat ttctcttgac atctgaaaca aaaaatatcc ataaaaatta tcttcttctt
     2581 ccataagact taaattcact ttatctacaa gactaaaaaa ctcatactta aaatcttgtg
     2641 gtatatctat atcaaatttc tcattagcac gatttgcctt tagcatagaa tgagtattta
     2701 taatttcact tgctttatta taaagctctt ttgcttgttt atcaaaataa ttttccatac
     2761 attatcccct tattaaacta taagattcaa aatatgattt tacaaactct tcattttcta
     2821 tagctttttt atatacttca atataactgt ttctaatatc cttcataata cctatcatta
     2881 aatctacagg atacattttt aaaaattcaa taaatctatt aatatagtgg tttgattcat
     2941 atttatcatt cttaatattt aattctaagt cttttagaat gttcatagct gatagataaa
     3001 gtcttgtatg actctcattt tttactcttt ctacaataga ctcatcaata gattctccta
     3061 aaaaaacatc ttcataggat attaatggtt cagagtttga ttcaataaaa cttataaatt
     3121 cttctgcaat aactttacct acattaccct ttacaacatt taaaaatact gctctaggaa
     3181 tagaattatt tttttcttta taaactttat aaattttaga tactctctca taacttctag
     3241 gagtggctct tacatcatct tcatttattt tatgcagata ttctggaaaa gtggaaataa
     3301 actcgataac ttttctttca ataccctcat ctattgccca ttttatccat tgtgtatggt
     3361 cactctccat atttaaccaa acaaacctat tttcttgggc tgcatccata tctaccactt
     3421 gataatcaaa atctgaacca tatttacttg atggattcat tgctgctaaa atctttacat
     3481 catcatgcag tttatatcca ttaatttctc tatttaaaat taaattcata agttcttgct
     3541 gtactgtatg ctcacaacga tttatctcat ctataaataa aagaactgtc ttacttttag
     3601 atatctcttc atcaatttct cttaatttgt tatgaacagc atacactgtt gttttctttt
     3661 cagtcttata tccattagaa ttaactccta cataagattc tatagttgga agaccaccta
     3721 tttcaccctc tttaagtaag tttccatcaa taacaattaa actccaatca ttttctttgg
     3781 caagcttatt tgctaaagct gtttttccta ttccactttc acctactatt aaaggtactt
     3841 ctccagtgga taatattaag tcaacgcttt ttaatgtgtc tataaaattc atttttctct
     3901 ctcctacata atctttaatt tctcatctac agctattttt tttgctgtct tacttccata
     3961 tttataaata aacataattt tatctattgg tatactttcg ctatttctat ctataacact
     4021 acaattcaaa aaatctctaa tatacttttc ctcaacatct tctttggata atacttcttt
     4081 taatacactc tctaattcat ctttagatac ttttttcaga atgtacttaa tcactaaaat
     4141 attcactttt aaaaattcca acattttatt tttatctaaa tcagttataa agctaatagc
     4201 tgcttcatta ttttttatag ctataagttc tgcattataa ctaggtgaat ctatatatct
     4261 caaggcatca taacttattc tcactgcctc ctcttgtaca ctttcataag gttgttttat
     4321 aaactttatc gaatcataat tttttcttac tgctaacagt tgtaattctt cacttggatt
     4381 tttagcatat ttaattgccc atcctgcttg atttatagcc atttcaataa ctttatcagt
     4441 tgggtttttg atataatcca gtatactcca tccctcattt actgctttta tcatcatatc
     4501 ttctgttgga ttatctataa atttaattgc tctaatatta ttatctattg ctagttcttg
     4561 catctctctg gttggattat ttatatattc tagtacaagc ccattttctt taatagctaa
     4621 caatttcatt tcatcagttg gattatctat tgtagctata atattgggat tattttttat
     4681 catttcaata actctcaatt tttccataat gtgcctttct ttctataatt atttttatat
     4741 ctatattaat tataataatc tattcctatt tatataattg tttcttatta taattaatat
     4801 actttttaat caaatttaaa cagaataatt ataccaatat ataaaaaaat ttctaaaaaa
     4861 caataaaatt aagttataaa caccaatata tttctattat ttcaatacgt atacaattag
     4921 attagaatct aacgctagta ataaaaaatt actttcccaa agtagatata agcctcattt
     4981 tatcgttcaa ataatgaaaa tatatttgat ttcatgcaaa aagagtgcct aatgaactaa
     5041 aaagttcatt ttgagacact cattttttta tataagttta tatagttttt aatcgttcgc
     5101 attcaaccac tcagttaaga cttttatata tttctcattt tcttcaacga atggcatatg
     5161 tcttgaatac tcaaataatt cccacttact attaggtatt ctatcataca tagtctttgc
     5221 aatatatggt gaacataaat ctattgctcc actagttact agacaaggct cttttatttc
     5281 atgtaatcta tctgtaaatt catatccaga aagagttcct gtaggagaaa attcattttg
     5341 tccccatcct acaatatatg cttcagaacc tgatttttta ggtcttctca ggcactctgg
     5401 agaatcttct gtcacttcac ctgcacaata catttccata aatctttcta atgcatcatt
     5461 atattctttg ctagagtaat ctccagtatt tactgcatca agtaatgctt tttggtcaac
     5521 ctcactcata tatgatattc ttcttttttg ttctttctcc caaagttttg cagaagaaag
     5581 agtagatgaa aggatgtaag acttaatacc ttttggttta tattcaatag cataccaaat
     5641 agcctgcata cctccccaag attgacctaa cagatgaatt tcatcaagtc ctagatgttt
     5701 tcttagttca ataagctcct ctatccaagt atctgcatta aatagctcag gatgcccttc
     5761 tacaaatgaa tttccacaac caatttggtc atacattatt acttgtctac cactttcagc
     5821 tatcttatcc aatacctcaa aatagttgtg tgtagaacct ggacctccat gaagtaatac
     5881 taatggcttc ttcccttccg tattttctcc tactatacgg taatacgttt taaaaccttt
     5941 aaaaggcata tatccttcag taattttcat gtttatctcc tccaatttgt aattataaac
     6001 aataatcaag ttcattaaca atactattta aaacctctta tacatatttg attatgtatt
     6061 ttaatcttta tacctacttt tataaatagt ataacataaa agttaaaaat ctctatacta
     6121 aaccaattat aaaattatat taactatata attttatttt ttaataatag tatatacata
     6181 tttgattatt ttcatttgct atttaaaatc aattttaagt tttcttctta taataaactt
     6241 cctctttgtg gtctcatgtt agtctctaaa tttaaaattt tacaaaaaat tttcataaaa
     6301 taaaattata ttgattgtat ctaaacaaat agggcaataa aataattaag tatagttact
     6361 tacctttcaa gcaatattag ttttatgtta gaattttatt atattgattt acaggaggtt
     6421 tgcatttgaa taatattaat tcacttaaag taataaaatt atctcttgga tgttctcttg
     6481 ctatatttat tgcttggcta ttaaaattag aatattcaat ggttgctgga gttatagtac
     6541 tacttacagt aaaggacact aaaagagaaa ctcttaaagg ctccattgga aagatttatg
     6601 gttttctttt atgtactatt ttttcatatt tatgttttaa tattttagga tataatttga
     6661 cttcattttc aatatttata tttataatta taccactttg ttttttgtta aatattcaag
     6721 atgttattgc tatgtgtgta gtcatagcat cccattacta ccttcaagga gaaacttcta
     6781 tcaaatggat tttaaatgaa gctggaatat ttgcagtagg aactggaata ggtgtcttaa
     6841 taaatatgta tattccaaca aatatacata aaatccatga agttcaaaaa aagttacagg
     6901 aagaagtgag tattgtactt atagacattg cagatattat tgtaaatcct aaaaaagaaa
     6961 atggatatag tagagattta tatacattaa attcacttat tgacagcagt atttctgaaa
     7021 cttacgataa tattaataat actttattaa gtgatactag attcttctta gaacatatgg
     7081 atattataaa aagccaacgg gatatcttag aaaatttgta tagttatgta tctcaactaa
     7141 attctacacc accacaagct catattctat ctgcttttat acataagata ggttatactg
     7201 aatttgaagc tgaaacaggc aatcttcttc ttgaagaatt aaagagacta atgcttagta
     7261 tgaaaaacca gcctctgcct gttgacagaa cagagtttga aaatagagct attttattcc
     7321 tatgcttgac tgagttaaaa cagtttttag ttaatcgtaa acatgctcag atacttagag
     7381 ataataattt ttataaataa aaaggggaga aatctagcag ttgacctgac tacaaaatat
     7441 cagatataat attaaatgcg cccctagtaa gagggcgcaa tgtttataac ttattctact
     7501 gtcatgatta aatcattatt catatcgaac atacattatt tgaccaagtc caatattagc
     7561 tttttcatca gtgatttcta ttttaatagt cacatcattt tttttacagt acttcgctaa
     7621 ttctgcacca gaacgatttt taccactaaa atctaaagaa aatggcttat catatttaaa
     7681 aggatattca acaggtttac cctctggtgc taatgcaaac atcccatatg gtgtgttcat
     7741 aaatcctatt acagcaatcg taagatttga tgggtctaaa tttgattcac tacctgtaaa
     7801 tgtaattgta tttactgatg aattaactac actacatcta acaccttcat acattacatg
     7861 tttttcattt atatcttctc ctttttttcc aaaatttcca acagcctttg ccccttcttg
     7921 atgtggtaac atagtgtgct ttccaggtgg tgctggtttc tgtgtctgtt ctggttttac
     7981 cgtctgtact attgcaccaa cttttggata tgctgtctta tcaaatggta atgggtggct
     8041 aagactcttg tatatgatat cctttcctgc tgatttatta gcatcaatat ctacatgata
     8101 caaacgccca tcaccaaaac ggataagatt ccactggtgg tcatttgatg tgctgtgtac
     8161 ataataagat tcaattccca tagcatcaca caaagctttc atgctcctag ccattcctga
     8221 gcatgcacct tttttagtaa ccaatgtata ggcagtattt gctccctcta ctgcattcca
     8281 gtcaacatat gttgtgttat ttttaatgtg attgtaggca actaaaatct tagcatctgt
     8341 ggtcatattc tttgtgattt tcttgttcat aaaatctgct gttgcttgtg ctactgagtt
     8401 tagttgggct tgtgacagct ttggaccata tacgctattg gttccagtga catagctttt
     8461 tggtgttttt gctgttacct ctttggctgt cataccataa actgtcatac tcatacctga
     8521 gattaaaact attgttgtaa tcaataactt ggtagttaac ttcctaattt tcttcatact
     8581 taatattctc ctttataaaa cattgttact tcctattctc taccattaat aaaattaatt
     8641 tagtatttaa aaaggtggat tgtcaacatg tatatttctc cattcataca ttcgtgaaat
     8701 atttaaattt tatggaaaat ctaatagata ttttctagat aatttgtata caatacaact
     8761 cgcaaatcag ggtatttgct gttagtttga gaaaatgatg atgattaata cattcggaat
     8821 ctttgaccta taataaatac cattgtcttc aatcattaat aatggtaaga gtaaagagaa
     8881 ttatcaataa tacagttaaa atcaactttg tatacatttc atacattctc tcccaacaac
     8941 attatacttc ttataatttg tatattcaat acgttttctg ggaaaatata ggatatatct
     9001 ataaaaatat aaaaaaggag ttgaacttaa aatttgatta aaaaaaatca attttaagac
     9061 aactcatttg tattataaaa atgctatata ttattattaa gtaagtcaat attttagata
     9121 tttatctatt tcttattgac ttacgcttat agcctaactt atttgtttag ttgatatata
     9181 acctagtttt aagcattatt aatatttaaa taatcaagta tcctttttgt ttcttgtagt
     9241 ttctgttctg cctcatttaa gttttcttga attatagaaa tatatattat atctatcaac
     9301 gtaagcattg ctattcttga agaaatagct ccttctctaa gtcttttttc tatatttggt
     9361 actactagct ttaaatcact aatcttacta agatgattgt cactatattt agttatacaa
     9421 atgaccttac atccttttaa ttttgcattt tctatagact ttattacttc ttttgattct
     9481 ccagagtaag atattgctat agctatatct tctttatcta catttgaaga taccataagt
     9541 tgtgtatgac tatctaaaga ggtaaatgcc tgtttattta tccttaaaag tttcatctgt
     9601 aaatctagtg caactaaagc cgaaccacct actccaaata tatatacatt tttagccttt
     9661 attatctgtt caactgcttc ttttattata tctttttcat tcaacaacct tgtttggttg
     9721 atagtctcta tgtttttgtt tgtaattttg tttataacac tatctatatt acaatcatag
     9781 ttttcatcta catatgtgta ttcattttct ttgcccatca aatctttagc tatctcaatt
     9841 tttaaatccc caaaacccga atatcccatt tttctagaaa acctaactat acttgctgta
     9901 cttgtttttg agtttgacgc caattctgat acagaaagct tacttatagc ctctgtatta
     9961 ttaagtatgt aatcagctat ttttttatct acttccgtta aatcttcata tatctgtttt
    10021 aattttaaaa tgcaactcat actctatcac ctctacctat ttactataat atttcttctt
    10081 agcaagtaaa catgctccta aatctggagt caacactggt ctcactatac caaatctcgt
    10141 tttattcaaa tattttttaa gtggctctaa tattaaatct cctgacttaa acactccacc
    10201 tgaataagat acctttatct ttgtaccttg ttcaaaatga tgctctaatc ctattataag
    10261 cctacttaat tcataagctg catcatcaaa tattttacta gcagtattat caccttcaat
    10321 aactgctttt aaacatatcg tagcaaactt tgctatttct attctatctc cttgtatttc
    10381 atcatttaca tattttatta tgtcataatc attctctata ttaagatgtc tttttattaa
    10441 atcatataat tttgtttttg aacaccttcc atcagactgc attgtgaaca tttttaaggt
    10501 agccattcct atataatacg ctgaaccttc atctcctaat acatagcccc atcctccaca
    10561 tctgtgaaga ttcccatctt tatctaaagc ctgtgctatt gaaccagtac ctgcaattat
    10621 atttatacct ttttccccat ttaaagaacc tgctaatgct atttctacat cattacctag
    10681 agtataattt atatgactat atgcattttt tgttgctact tctaatgcat acaatacttc
    10741 ttttattttt ccatatccag caagtccaac aaatgcatac gttatttctt ctacatttat
    10801 cttagcatct ttacaaactt cttccaaccc agttattaat aatttcgtta gattatcaaa
    10861 tcctatttga ttataatgac aagttccttt ggttatggtt cctactatat ttaattcttc
    10921 atctactaat gtaaatgttg ttttcgttcc tccaccatct acacctaaaa aatacatact
    10981 atcctcctac aatatcttta ataattcttt caatacttaa tatctaaaaa taaccttcca
    11041 atgctgtttt tttaatattg aaaggttatc agtactatta tttattttac aatttttcta
    11101 ttgattttaa agcttcactt atataacctt cttgtctatc taggatactc tttgcactat
    11161 ccttatctaa accacttttt atcataaata tagccaattt aacgctatta tctgcttctt
    11221 ctaagaattt ttctgcaaca tcatatttta catttgtagc tatcattatt attctttttg
    11281 ctctttcaac caacttttca tttgatgtct taacatctac catcaagttt gagtatactt
    11341 ttcccatctt aaccatagaa gctgttgtta acatattaca taccattttt tgagctgtac
    11401 cacttttcat tctagttgaa cccattatta cttctgcccc tactataatg tttattggta
    11461 aatccgcttt tttactcatt tcactattcg gattcatagt tattgatagt actgcacacc
    11521 ccaattcctt agcatactcc attgcaccta taacataagg agtccttcct gatgcagcta
    11581 taccacatat aacatcctta gatgtaactc ctctatctat tatatcttgc tttccaagtt
    11641 ctttatcatc ttcagcacct tctattgctt taaatattgc ttgatttcca ccagctatta
    11701 tagcttgaac aagctcaaaa tccactccgt aagttggagg acattctgtg gcatctagta
    11761 ttcctatcct accactggtg cctgctccta tatagaataa tctacctccc tgcttcattc
    11821 tatctactat tatattaaca gcttttgcta tactctcctt ttgttcttca acagcatagg
    11881 ctacagtttt atcttcgtta tttattaatt ctattatgcc taatgtatct tctttatcta
    11941 tttgcaatgt attcttattt ctaccttctg taactaaatt ttctaaagtt tttattaaca
    12001 tatcatttcc tcattttctt aatattaaat ttttaaacac attttaattc caactttcat
    12061 aattatattt ttataataaa ttaatatttt cataataaat tattttgttg agggtttaaa
    12121 attaaacttt tgccatggtt taatataatc taatataaat aattcttctt ttcttatata
    12181 tcctactaca ttcgatttac cactgttttt catatcagtc aaggctattt gtaactcccc
    12241 tgcataatga ccatattcac tactttcaat tactatatct cctcttttta ttattttagg
    12301 agtattaaat agttcaaatt tgtatccttt atatttaaca cgagattgag tagaccttat
    12361 cagactgtca gatatgtccc ctctattaaa atgtatttct tcaaagagta tcttcttctc
    12421 aacttctcgt atattttcct ctattgctac atcaaatgta accatatctt ttctcataga
    12481 acctaatacc tttagctcct catatgttgg ataacaattt gatattatta tatcatttat
    12541 attattcata gctattatat gctttacttg aatatctata ggtagatttc tgtgcatctc
    12601 aattgttgga agcccatcag ttacaggcca tggtccaaat gtagtttcat tttgacttgt
    12661 tacaaaaact gctgttctta atccatactt attaaatctt tctgtacatt ttataaagtg
    12721 ttctaaattt aatccactat atctatgtgg ataaaagtta tgacatcctg tcaagttttc
    12781 tttatttggt tggtagtcca ttattgtatc tatataatta gtattattac tcatattgat
    12841 ttctatttta agattttgag gattaaaagt cattaatgcc tcttcagaac ctgtaaatcc
    12901 tatatcaagc cttattccgt ctgccttcgt ctttttaaaa aaagtcaaat ctttgtagct
    12961 tatttctaat tcaccaaata ctctgggatt tacatcaagt attacctcaa aacctttaaa
    13021 cttagcgtat tcatttatac gtttaaattt tttaattata ttttctttag tatctttaac
    13081 tgataataaa catgaaaata tacgtgtaaa tccattttca gcagctttat ctatataatc
    13141 atatatttcc ttagatgttg ttttttctgg ataaattgat attcctaatc ttcccatctg
    13201 tgtcatctcc ttatatccta tatgtgttta aatttatttc gaattacacg aaactttttt
    13261 aaaaatttgg tgaaaaaaag tttcatatat atttataaaa aaagaaaagt ttaccttttc
    13321 tttttttata aacaatcaac aaaatatctt cgttacttat ttcataactg ttatactttg
    13381 aaatttatac taatctaata tagtttttaa tttccaatat agtttctaat taataagctt
    13441 cttgctcttc aactttttct tcatgaagca atctcttatc gtacatcttg acaaatggat
    13501 agtaaattat tattgatata gctatacata ataagttaag aactgaagct ctccaatctc
    13561 caccagtggc taaatatgcc cctactggtc ctggtaatgt ccaaggagca gtaactacta
    13621 ctctggatac taaattagca ctcatagcaa accatgaaac tgttgccatt actattggtg
    13681 ctacaacaaa tggtattatt aatattgggt ttaatactat tggtgctcca aatattattg
    13741 gttcatttat attgaatatt gctggtatta cagttgcttt tcctaaagac tttccataag
    13801 ctgattttgc tctaaatgca agaagtaaag ctaagcctat tgtagctcca gaacctccaa
    13861 tccatataaa ccattgaaaa aagggttcag cagcaatacc tggaactgct tgacccgcag
    13921 catatgaagc tgtattagca tctaataatt gtatccataa aggtcttgcc aatgaaccta
    13981 ttattgatac accatgtatt ccaaatgacc aaaaaaacgt tattaaaaat attagtataa
    14041 ttactgatgg taatgtgtca gtggctgaaa ctaatggagt tactaattta gctatgaagc
    14101 catgccaatc aaaccctagg aaataagtaa caatagccat taaaattatt attaatgcgg
    14161 ctggtgtcag agcttcaaaa gaccttgtga ctgatgctgg aactgcttct ggcatggtta
    14221 tcttgaattt agatttgtca gtaaatctat aaatctcaac acctattata gatgttacaa
    14281 tagcaacaaa cattgaacct ccaccaagat tagccattgg catttgccat ccttgaggaa
    14341 ttgaattata ccaagctaaa agttctggac tcttttcaac tatctttaat aactcagggg
    14401 taagaccctc tattgcagta ggaactattg tcaaaaggaa tgtagctgta gctaataaac
    14461 ctcctgtcaa tccatctaac ttatatgact ttgccaaact ataacctatg ccaaatgtag
    14521 aatatactga tataataaaa aatgtcattc tatatggtag taatattgta actgcatttt
    14581 cctttagata ctgagttacc ccccatgaat ctggtaatgg aggaaatgct aatatcaaga
    14641 aaaatgaccc aactattata agtggtaatg aagctacgat tccatctctt acagctctta
    14701 agtgacgttg ttctgccaat ctggccatag aagttgataa tttagtgtct aaaaattctg
    14761 taaatttatc tagcatcttt tctctcctta attaatattt atttttatta tcattaaaat
    14821 ttttataaaa tcaactttct tctaatctaa caacactgca actactattt actcaacagt
    14881 tcttgaactt gttttaataa ctttggtcct cctaatggac tataagcttg tgcttgtatt
    14941 aatgcacatg gtacactaac ctcatcagca aaagctttta aatagtcaaa tctatgtctg
    15001 acttgtggag ctaccatagc aatatcccat ccatttttaa cttcattctc aaactcttga
    15061 gtaccaacag ccaaaacatc tatatctatt ccattttttg ctccttcttt ttgtaatgca
    15121 ttaactgcta tagcacttga catccctgat gaacaaacaa ataatactct catattgatt
    15181 ccccctgttt ttttatttct tttcaatcat tatagcatgt atttttgatt acaggaatac
    15241 gtttgtatat attttttcat attttacatt ttaaattgta attttatttc atgcatttat
    15301 atcttgcttt aattgcttta tttatctaat cattcttttg tctaaaatta cacactactt
    15361 aaaatactca tatcttttct taaaaaagaa aaaagactat cttattatta acataaaata
    15421 gtctcaatac ttttttaaat atgtattcct ttatatatcc agaagtaacc tattattgca
    15481 aatgataaag caaataaaat atacagtcta aaaaatccca aagaaaaacc tctcttagtt
    15541 tcaacaaagt atcttgtata tgcaactgca aaagatgtaa ttaatgaatt tcctataaca
    15601 actccaaatc tattatctat tccaaatata gataataaca aaggaaaaac tacagtactt
    15661 acaagagatg aaactattag tattaatcca cttttaaaac ttatagttgg aatattataa
    15721 tctgttcttt gatttttctc catttgtttc ttagtatttt tattactttt tgtacttttt
    15781 gcatttttat aattattatt tttctttctt ttcttttttt tattattaga catgtcattt
    15841 acctccaaaa ggtttaggtg ttatattccc taaaataact ttatttttag cccctgttgc
    15901 agatattaca ttagaaaaag aattatttaa tgtttcattg cccaagatta caaatgccaa
    15961 agcctccttt gcatcagaag aatacccata ttcatcttga gttaatactt caacctctaa
    16021 taataactct tttatatatc ctattaaagt tagattatga gctcctccac ctccaattaa
    16081 taaagtatct acattaacct ttggaagtat gaagttttta taattataat atatagcttt
    16141 tgccgtaaac atagttactg ttgctatcaa atcatattta tctacatgtt tatatttgtt
    16201 aagcatgtta tccaaataaa cttgtccaaa tacctctctt ccagtgcttt taggtggcgc
    16261 ttgactaaga tacttatgac tcatcaaatc ttttaacatt tcttcattaa ttttaccttt
    16321 tgatgcaaag tatccatttt tatcatactt tctattaaat aatctttgac atactccatc
    16381 tattatcata tttcctggtc ctgtatcaaa tgcaaataca tcatctatgt tacatgattt
    16441 aggtattata gtaatatttc ctattccacc aatattttga agtgctaaat ttttattgtt
    16501 atcactatat aataaaaatt cactatatgg tactaatgga gcaccttctc cacctgctgc
    16561 tatatccatt actctaaaat tagatattac ctttgtattt gtttcatatg ctataactgc
    16621 tggttcacct atttgaagcg ttgaagatac aaaattatta taacttcttg gtatatgaaa
    16681 gattgtttga ccatgagatg cgataaaatc caaatttgct atatgaaagt ttgctttatg
    16741 acacactgat tttacagctt tactaaataa atatccaagc ttaaaattta agctacagat
    16801 taaatcaaca ctcgattcct cttctataca gcactttctt atttcgtctt ttatatcttt
    16861 aggaatttct agagttataa attctatttg cttaacttta gtatttctac cattcccact
    16921 aatttcagct agtactgcat caactccatc taaggaagtt cctgacatta aacctacact
    16981 atacatagtt atcatccttt taagtttata gttattcctc cccaaatcaa ggtattaagt
    17041 ttaataattt tagaattaat cttatttcat ctttaattac gataatttac tcttacgaaa
    17101 ttaatcgagt taatcttata cacgtttttt accttagcta aatcttacat taatttattt
    17161 tcagtgtcaa tgtaatacca tgtaattttt tttcacaaac aaaacatatt ctctctccaa
    17221 aaaccatatt aaaatagtta ctacaaataa aaaacatacc aggtacctat ctgatatgtt
    17281 tttcatatat aataattatt attttataat atagatggag catcatttaa ggcactaatt
    17341 aaatcttcac tattttcaag aactaaattt attcttattg tatatgtcga tttgtatatg
    17401 atgatagatt ttatagtcta ataacctaac tatctatgct taaataatcc gatatatcat
    17461 aaaagtagat attaaaaatt gtatatgaac caattttcga acatacctca atctcatgcc
    17521 ctaaactatc tatcattttc tttacaaaat acatccccat tccagtagac ttatacaatt
    17581 gatttcttcc atttttcccc gtaaatccct tgtcaaaaac cctagatata tcttcctcat
    17641 ttatacctat accaaaatct tttatagata ataccactcc attttctaac ttttttgaat
    17701 taaattcaat cttaccaact tcctttgaat actttatagc attattaata atttggtcta
    17761 aaacatatga catgcattta gaatctgtgt aaacatcatt ttctaattca ttcaaactaa
    17821 cttctacatt attttttata agcaaaaatg aattattttt tatagacatt tttaccaatt
    17881 tttctaaatt aaatttattt ataaatacat cttcaaacat agtgttgctt ctactactat
    17941 acaaaataga gtttactaaa aaatttatct ttgcaacctg attcttaata tccaaactat
    18001 cttctatgct acttaaccta tctgtaatta tacttaaaga agatattgga atttttattt
    18061 catgaaccca tttagctatg tactcatcca attcttttaa tgattgttta taagtctcta
    18121 tgtcactatt attttttatt tttaagtttt ctataatatc ttttattaga ttttcttcaa
    18181 aagattgtcc atcaactaaa taactatcta tttcaccact attttctata caattatata
    18241 aatttgtgta actatttcta aaatttatat aatctataac aaaaaatacc attattataa
    18301 acagcactaa aaaatctaaa tatattaact ctgaatattt atttttaaaa atatctatag
    18361 caaataagta gatatttatt atactaacta caactaaagg tagagcaata tacttagacc
    18421 tacctttcaa atattttact agcattgtat tatatatcct atccccttct tagtttttat
    18481 aaaatcatca aaacccagtt ctttaacttt acttctcaat ctattcatat ttacagtaag
    18541 tgcattgtct gtcacaaact cgtcattatc ccatagagtc atcataagac tttcccttga
    18601 tacaacccta ttcttatttt ttaataataa tgttaaaatt tttatttcgt ttttagtcaa
    18661 ctctatactt ttatccttat acttatgttt tataatccct ttccccacat caaacatcaa
    18721 atcttcacaa tacaaaatac tattagaatc actataatta tagactcttc ttattatacc
    18781 atttattttg gtaaccaata tttctataga aaatggtttg gtaatgtaat catctgctcc
    18841 attatttatg cccattatta aatccatatc agaatctctt gatgataaaa atattaatgg
    18901 tacatttgaa atagctctta ttttttcgca ccagtaaaat ccattatata atggtaaatt
    18961 tacatctaaa agtactacat ctggtttttt atctataaat tcatctaata ctacctcaaa
    19021 atcatcaatt aattctactt taaatcccca tttttcaagt gctaacgcaa tctcttttga
    19081 taaatcaata tcgtcctcta ctaataaaat tctatacatt tgtatattct ccattatcct
    19141 aatatttcac tatgctatga attattaata tcataacata ttttatatga atttattacc
    19201 caaattattt agttaatcaa caaggagact cttattacaa gaatctcctt tctctttatt
    19261 aatatatcaa ctaattttta tacactacac tcttaaactt attaacagat actgctccat
    19321 atattatgaa tattatcaaa catatcacta aacttagtat atatatacca aataaatcgg
    19381 tcatcaataa atctcctgct aatctcaatg caaaataact agatatagtt gcacttaaca
    19441 ttggcaaagt ataaaaaata gctacttctt taagtatagc tctatttata tctttttctg
    19501 tagtacctat ttttaacaaa atcttatatt tctctttatc ttcatatgca tcactatata
    19561 ttttcatata tattatactt ccagctacaa ttgcaaagac taagaataaa aacacaagca
    19621 ctacatatgc aaacttcatc cattgactct caccttgagc tttatatcca ttttgaatat
    19681 acccattttt taaacttaaa ttcttttcaa tattgttgaa cattacttga ctattttctt
    19741 cttgaaatac ctttgcacca taaaaataca cttgttgacc cttatctctt agtttaaaat
    19801 atgtatcatc atttaccact ataatacttt gattaagtcc tgtccctagt actggaactt
    19861 ttacttctcc ccttgaaata ttatataact gaccatcaag ttttatcttg gcttcttttg
    19921 tagctattga tgctatcgtt tgagggcttt ttaactctat tacattattt ccactaacta
    19981 atctttcacc atactctttt aattctttat cattaccatt cactttaaga gtattacaaa
    20041 aatcactata tttcattata gtatctgttg tatcataagc ttcttttata tctgttttct
    20101 ttaaaattgt tagttctgga tttactgagt actttatctt attagtatct tttattatat
    20161 tctctatttg ttttttattc acttcatctt tatccattga aactatgcta atagtgtaca
    20221 catttctttg ttcttgggca ttcttatgta tatgcttcat agcaactgaa gcaccaagag
    20281 ttgatattgt tgtagttata attatagcta ttatagcata agttttatag tttttattta
    20341 atcggtagtt tatattgttt attgcaatta tattatttcc attaaataat atttttttat
    20401 ttttgattat aatatcaaat ataacaggca taactgattt gaataatcca taagtaccta
    20461 ctattattat acctataaca ggtagtacac tagttatatc tccagttctt atattggtag
    20521 aaagatagta gccatatcct attactataa ttgatactat agctaatata tatataccta
    20581 ttcctacctt tggtattttt tcttgttttt tagatatatt gattagattt attacactac
    20641 ttctacatat tgttataaaa ccttttacag ccattattat aaatatagaa ataaagatta
    20701 aagtagcata tagtatagct tctatactaa gtccattaga tacctttata ttaaatccag
    20761 ataactttat tatcactact tgaaaaaatc tagatgttat tatccctata attattcctg
    20821 ttatacaaga acttattcct ataagcatat tttctacaaa atatattttt cctatagtat
    20881 ataaatctaa tcccataaaa gacaatattc caatttcttt agacctattc ttaaaaaata
    20941 tatttgttgc ataccatata aagaaaaata aaaatactga tagtatcatt attacagcta
    21001 ctaacactga tagtgtaaat tttttatttt cctcttgtaa cacatttata gcatcaccat
    21061 atcttaataa ttcaaaatta gttagcacaa ctactgaaaa aaccatagat ataaaaaatg
    21121 ctagataagt tcttatgtta ctcttaaaat tattataagc aattccaagt atactcactt
    21181 acatctcacc tcccatagag gctagcatat ccataatttt tccataaaat tcttttctac
    21241 tatttccttt gtttaattta cactttatat ttccatcatt tatcatatat acttcatttg
    21301 aataacttgc tgttagaggg tcatgtgtaa tcattataat agtagcgtta ttttctctgt
    21361 ttattttttc taatgattct aaaagttcat atgctgattt agagtctaaa gcaccagttg
    21421 gctcatcagc aaatatgact gttggatttg taattaatga cctagctgct gcgcctcttt
    21481 gtttttgtcc tcctgataac tgatatggat atttatctaa atgattttct aatccaaatt
    21541 ttttagctat agaaaatacc ttagcttcta tctccttact tttctttttt cctaatgcta
    21601 gaggaagtgc tatattgtcc attagtttca tattgtctaa tagattatag tcttgaaata
    21661 taaaccctat tttttctctt cttaattttg atagttcatt attttttact tttgatatat
    21721 taattccatc tagtattatt tctcctgaag tttgtttgtc aagtgtagac attaaattta
    21781 gcaatgttgt ctttcctgca ccagatggac ccattattga tataaaatca ccttcattga
    21841 ctgtaagaga tatatttttt aatacatttg ttttaaatcc ttttattcca taatcttttg
    21901 atatattttt tatttttaat atttctttca taacaatagc ctccagttgc taatttttta
    21961 atatatattt attttaaagg ttttatataa ataaatcctt aagtaaatat tacattttaa
    22021 ctgttagcat tacacttttg taacatatgg aagactatta taattatagt agaaatatct
    22081 taaaataaaa gcatgattta cttctttgta taaacaaaga aaagaagctc ctaagaagcc
    22141 tctaatctat acaattattc ttctctataa aaaaccaaaa tacacattga ttgtggcaaa
    22201 tacagatact ataaacaagt gatattacta ctatatatta aaacaattat tcctgaagat
    22261 aattcaataa gactatcaag caataagcta agcatccaaa aagacttaat accattaatg
    22321 tataattata cccaatatta atgcttaaaa aaccagcaac agttggaata atcagagatg
    22381 aacctcccat aaatatactt aaagctatta attggctact acttctaagt tttttaggag
    22441 aaacttcaaa tattaatctt tttgaagtaa ttaaaattaa aggagtagaa aacacttgaa
    22501 aaacacacag tataataatg atatttgaat catttgttaa agcaaataat agaaactgaa
    22561 ctgttatcat aatagcactt aattttaata agtttaaact gctatatttt tttaataaat
    22621 aagaaccagc cagatatgtt ggtatctcta acaatgactg taaagaccac tttaaagata
    22681 tctgagaatt tgtagcattt aaagctatca ttttatctat tacagtacag ttatttgcta
    22741 ccaccattga gtataataag aataaaatac atactagtaa gatatatttt ttatctttta
    22801 ataattcaat aatatcttta ttagttacat ttattttctt attaatcttt tcaatatcag
    22861 gtaataatag tatatttata ataagtaata ctacaattaa accaatcgct acagataatc
    22921 caaaatatga gaatctaaga atcaagtaag atgctaccat acttccaata gcccatccaa
    22981 tcgacccaaa agtcttaata aatgacaaat aattattaat attatctcca caacctatta
    23041 tccatgtatc atataaacta cagcaagtat ttaataatcc tcctgataaa gcaacaagta
    23101 ataagtatat tataaaagtt gcagattcag tagaaaacat aataactgat gcaattccat
    23161 aaactgataa actaattaaa acaatttttt tcattgtttg atacttatca gctaatactc
    23221 caaataataa ttgaaataat atattggtta ttgcataact cgataatata attcctcttt
    23281 caaacgctga gtaacctaat tttgataaga aaggtgtgaa ttttgttgaa gcaaaggcaa
    23341 aaataatata tgagaaaaaa tagaatatga taaatttaaa tttaatcgct ttattaatca
    23401 taatcaatca aaattgataa ctttaatacc actatttcct tcctgattta agtttgaaag
    23461 atgatatttt accgtattag gattctctac aataactaaa ggaatatata aagtattttc
    23521 aagtaactta ttatcaattt ctactaactt ttcccccata ttaacttctt gaccttgttt
    23581 aacttctaat ttaaagtttt ctttttttgt tgttgcactg tccaatccaa tatgaataag
    23641 aatttgaaca tcattttgca atttaattcc tatagcatgg ttagtttgag caataaaact
    23701 tattactcct ttagtcggtg atttaagaat attgtccttt gctatcatag caaatccatc
    23761 tcccattacc ttagttgaaa atactttatc aggaatttct ccaagattaa ttatttttcc
    23821 atcaatgtat gaattaattg taattgcttc tttttttctt ttaaagaaca ttatagacac
    23881 tcctctacat aattaacttt attctaatta tcattacaaa taacgatatt aagcatactg
    23941 caattgagga aaaaagagcc ttatagctct ttccccattg tagttcttta atactgctta
    24001 tgatttgttt aattccaaca aatttataaa tataggtaaa catgataaca atagttattg
    24061 tgtaaatttg gaatatctgc cctaataaga ctaaatagaa agcaatcatg ttttctttta
    24121 tctctttatt cttttttata ttgtaaataa catatgcact gtatactgca ctaaagttag
    24181 agattaaatt taaacttgca ttaacatcat tgtttaaaag ttgtgaaaat gaaatatttg
    24241 taaataatga tgtcaattct aaatacacta tatataaaac aggtaatatt agaaaacaaa
    24301 ccataaccac tgaaagaaat atattttcat cttttaatac tgctgtgata ttttttattt
    24361 tatttgttat catgtttttg ttctccttat ttaaaagttg gccagaaatc cttattagcc
    24421 acaatcattt catctaagat ttcttttgct acttttgcac ttggaacagt tttactcata
    24481 gtaaacgact gccataattt ttgataactt ttttctatcc atgcttctac agctaatttt
    24541 tcagaagcaa cttgttgttc cattaaacct ttttggaaag ttggaatttt acctatagac
    24601 ataggttcaa ccatatcttt tccaacaagg caaggaattt caaccattgc atcatctgca
    24661 aaattttcaa tagctccatt attaggaaca atcagtaaaa atctttcctg agtattaaat
    24721 gctaatgcac aagctaattc aacaataaat tgagaatgct cacttgcatc aaaccatgta
    24781 tcccttgctg tgccattttt tataattctt tcacattctt cgaatgtatc cttttctctt
    24841 ctatccataa tttcatttgc tcttgtataa tttggattag catgttcaac agtttcatca
    24901 gccattaaat aatattttaa ataagtatta ggtaatgtag ttggttctat ttctaataag
    24961 tcctttgctg ctctcatagt ttctaaccaa ctagattctt tgtgttgacc ttgaggtgta
    25021 aattcctcat atcctttttt agcacaatat tcttgtaatt taggcattaa atcatttcct
    25081 tctttgtcct taatacttgt ccaccacccg aaatgattca atccataata tctaacatca
    25141 aagtctttac gagaatttaa acctaaaact ctagcaaata tttcctctaa acatactggc
    25201 atatcacaaa tattaataat tcttgaattt ggtcttaata cacgacatgc ttctgcaact
    25261 atagctgctg gatttgaata attaagcatc caagcatttg gagaatattt ttccatataa
    25321 tcaatcattt cgattattgg acctattgtt cttaatccat aggcaattcc acctgcccca
    25381 caagtttctt gaccaacaac cccatatttt agtggaattt tttcatcttg ttcacgtaaa
    25441 gcatataaac caacacgaat ttgtgccatt acaaaatcaa tatcagtaaa tgcttcttct
    25501 ggatttgttg tataactaaa tttaatttct ggatttttct ctctaacaat tattgcacat
    25561 gcttcagcaa cttttctttg tctctcatca ttattatcat ataatttaat tgattcaata
    25621 ggaaatttag caacactttc aattaacatt gttacaattc cagcagtata agtactaccc
    25681 ccaccagcaa ttagtatcct ctgtcttttt ctttccatct ttccttctcc tttataataa
    25741 attttcaaat tcttctctta cacttggtac tgaaagccca ataataatct gaatagcttt
    25801 tccattatgc actaaaccat gtgcacctac tgccttaaaa tcttcttctt tagaaataat
    25861 tgagtcatct ttcaaggtta atctcaacct cgtagcacag tttgtaacat ctacaacatt
    25921 ttctgctcca ccaactaatt ttatgtattc agatgcttgt tgagaggctt tactcaattt
    25981 atttcctttt tcatctttag tttctaagta ttcattttta gtatatagtt ttgtttcttc
    26041 actatcttct tctctaccag gagttttcat atcaaacttc ttaattaaga aagtaaatac
    26101 aaagaaccag ataaatgaaa atataatccc tacaacaact tgaacaacat ataccttcca
    26161 gtgatacatt ccaagaggaa gccaatttaa tacaacccag ttaataattc ctccaccaaa
    26221 atcaccaaca actcctaagg caaacgaaat cgtttgcaag cacgcatcta aaaatgcatg
    26281 tactaggaat aaaagtggtg ctacaaataa aaatgtaaat tctaacggct cagtaattcc
    26341 agttaatact gcagtaagag tagcaggaat cattaaacct aatacttttt tctttttttc
    26401 tggctttgca gttacataga aagcaccaaa tacacctaat gaaccaaaca ccttcgataa
    26461 tccggataat gaaaatccga ttggatacat ttcctttaga gtcttagctg aagtttgaaa
    26521 atcctgaata tgagtagccc aatatactga tgtaccacct ggaacaacaa cactatcata
    26581 acaaattggt gcatatacaa aatgatgtaa tccagttggt attaaaatct tttgtaagaa
    26641 tgcataacac caaactccta tatttccact atttataaaa aacgtttgca aatgtctaat
    26701 aacattttga atatgaggcc aaataaaaca agttaataat gcaactggta tcataacaaa
    26761 gaaacaaatt gcaactacaa gtgatgagcc tctaaataat ccaataaaat ctggtagttc
    26821 tttatcataa aatctattat gaatataaat gacaatacct gatattaaca aagcaccaac
    26881 cataccagta tctaatgttt taataccagc aatgcttaca agtccacttc cagcacttat
    26941 ttcagctgcg aaatcaactc caaagctttt tccccaaaaa cttaacatag aacctacaaa
    27001 ataattaaaa gtcaaatacg ttgctaaagc ctccatacaa gctcttgctt gttgcttttt
    27061 tgcaagtgct attggtaaag aaatagcaaa taataatggt aattgattaa ataccatcca
    27121 agctccacta gatattacac cccaaaattg gtaccaaata ttttctggtg tagcaagtga
    27181 acccataatt gactgatttt gaaatacaat tgagaatcca accattatcc cagcaaaagc
    27241 aaataatagt gttggtgtaa acattgcccc tccaaaacgc tgtattttct tcatcatata
    27301 aattactccc ctcctcatat ttttagttta tctttggcct tagatatcta ttattttaac
    27361 aggttaataa atatatacaa tctttagggt acatttggag cttattcaca gtcaaataag
    27421 tttttgcaca tttttatgtt caaattctca taaaaaaaaa gaatgactac aatttgcaat
    27481 caatcccttc tgtaatcatt ctatgccttt tataaatact atatttaata aataataact
    27541 caatcaatat aaaatataac attgtcaatt tataactagg gtgcatttgt aaaaatgaga
    27601 tattagtcgc tgaaatataa attgattcat cacttaaatc agtcaatgta ttatttttaa
    27661 actctgtaat tgaaattatt ttagttccta ttaattttaa tcttctagca atattaagtg
    27721 tattctcatt ctcaccactt agggatataa taatcataac atcattttta ctgacaatat
    27781 tgtaaaaaga atcatcaaat gttcttccct caaaatcata tattatttct tgacatgata
    27841 agaacattct ctttatctgt tttgcaacta cattttgaat atcacctgaa ccataagcgt
    27901 atattgttct tgattcataa agaagtttac acaatgcatc ataatcttta tttttttgat
    27961 cttcaacata cttaattatt gaattacatg caatatcaaa tgactgattt tctatgacat
    28021 gaaccttttc tgattcccag cttaataata ctttaaactc actgaaacct tttaaatcta
    28081 attttttaac aaatcttgta atagttgcac gagacacatt acatttcata gcaagttcat
    28141 ttattgacat cttactacaa tgttttttat ttgcagttat atatttccat attaataaat
    28201 ctgtatcatt caatttatta taatttaaaa aaatcatttc ttctaatctc ataaactatt
    28261 acccccttta attaaaaatc gtcataaata ttataccaat attcaacatt aaattacagc
    28321 gtattcttat atttactatt tagcccataa aattgactat aaaaaatact gctataattg
    28381 atgtttaaaa aaatgtagtt ttaattttat tcttttatct aataattaat attttcaagt
    28441 tctagtgctt ttcttataca attatcatct ttaaaatcag cagtcctttt acaatctttt
    28501 actttaaatt ctggaatagt tttaaattcc tcatcacata ttccattctt atttaaatac
    28561 atacaacttg ccattctaac tattagacca ctatttttta aattaaacaa tacagggtct
    28621 atacaccctc catctccgcc agtagtttca ccaactaaag tcgcaaattt agtttcttta
    28681 caaaacattg caaatgactc tgatgatgaa tatatttttc tatcaacaag taagtatata
    28741 ttacccttaa attttgaatc atctgtagat tttatagtat aggaagtatc ttcaaaatca
    28801 ttaaaatctt ttataatttc tttaggtgca ttttccttta cacttgttgg taaattttct
    28861 acaggattta attttatatt tcttgcattt gtatattgtt ttactatttc attattattt
    28921 ctataaattc tataaccatt tattttgaca tcatttttta tgagtttaga tacgattccc
    28981 tgccaataac tatcacttcc acctaaatta cctcttatat caataattaa agctttatgt
    29041 ttttctaaag tgtcaatata atctccaatt atttttaaat cattatttat agagccattc
    29101 tttgatgaca ttgatggtaa atacatatat ccaatctgac ccttaataac atcctttaaa
    29161 attaattctt tttttacaaa aatatcatct ggcattttta ttttaagatt catagagtca
    29221 tatctatcta caactttttt atcattaaga aaatcatacc aatcattatt agagtatgat
    29281 ttcttaaaaa gttcatatct tttcttatta tctattactt ctgtgtgttt attatttaaa
    29341 tcagataata tagatgacat ttcttctata aattcttcat cattttcagt gttttttatt
    29401 cgttttgtat attcatcctt atttgctaac caatcaatat tattaagcct cttatttaca
    29461 cctagatatg gatatcctgt ctttacaaca ttatacacat aattaaagtc atccaccttt
    29521 tcctcttcag acaactgatt cttttgagaa taagtagaat tacctaataa gattataaat
    29581 gctaaaataa ttactaaaaa taatactttc tttttcatgt aattctcatc cactttcaga
    29641 ttttatattt taatacattg tatcattatt ttattatcac ctaaacagtt aaaagaaatt
    29701 cttgaagata tattccacta ttattctctt taaaaatttt tatttgtatt ttcaaaatta
    29761 tttcatgaaa gttataaaat aacaattata ttcaaatatc tattttactg ctatatcctg
    29821 aaggtaaatt cttatcagtg atatactaaa aaagatatgc ta
//
LOCUS       DAEPHU010000054        28516 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 01A10CD0081
            SAMN05941466-rid12468953.denovo.054, whole genome shotgun sequence.
ACCESSION   DAEPHU010000054 DAEPHU010000000
VERSION     DAEPHU010000054.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941466
            Sequence Read Archive: SRR6291087
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 28516)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 28516)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068158.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 22:43:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,892
            CDSs (total)                      :: 3,805
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 87
            rRNAs                             :: 8, 1, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 55
            CDSs (without protein)            :: 55
            Pseudo Genes (ambiguous residues) :: 0 of 55
            Pseudo Genes (frameshifted)       :: 21 of 55
            Pseudo Genes (incomplete)         :: 28 of 55
            Pseudo Genes (internal stop)      :: 16 of 55
            Pseudo Genes (multiple problems)  :: 8 of 55
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..28516
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941466-rid12468953.denovo.054"
                     /strain="01A10CD0081"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            391..2886
                     /locus_tag="KR231_002462"
     CDS             391..2886
                     /locus_tag="KR231_002462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HBH0004829.1"
                     /translation="MPENNNQLLEEITLLLNEGKVAINKAENQNLILILGGTGCGKST
                     AINYLAGCVMMEVEDEDTGISYIDCLDPVAEIGSGAVSQTLYPNIVNMRKPIEGMDAK
                     LCDTAGFSDNRGVAHDISAAVSLGEVFKNSASICAVIVLIPEADILDSRLTKVLDLFQ
                     QLNMCLHKENFKGSITFFISKSFLGRTEKQIYNVIKRKYEQLCENLDSNIEEKAWLFE
                     ELLKDNGKNIHLCKPLASDEREGLLKQVLELDEVKDKTSAFQYPISADARLVLDTLIK
                     EIQNNIVSSLEDYVKAYTEDFINIIGSITMIQEIAKYDEVVKVFKNWLESTTSLTIER
                     FINVLAKQSGLFLQDSCMKLQNKIKGNLDIIDALSKYTEHGTGEILLPSVHMEFIIEK
                     ASKKIMEQNFIIIRKNLEKVLVSYEVQKQVFTLPNREKLMEVANKKDYVYSVSDFNSI
                     LTNVTVTQNEELEDSITRLSAYGEEGNEIIREFIGKYILNPFIVKTININDKKGIEIR
                     ALIPNLVISSVLEYFKNRKVDDNVSTFMFFAKDTIYMDDNLGMNFASEKNIILASNNL
                     DVGSNVKINVSGKSGELVDNSMYGKNGEDGRDAGNIYLYIKEEIRNYRLTLIANGGNG
                     SKGIDGENGETGASGSNGADAGYTSYFHGQMFKGYFEKGTSGKKGEKGGAGGNAGRGG
                     NAGKKGNIYFISDSEEQKNRIINHCDITVKDGEAGPNGRPGLGGYGGSGGYHGYNTLS
                     FSPSGIDKTVYYTGYFTSWDYKLDSIIKYHIEFSGGSWNEGKTGPAREYAEYGDRGDN
                     GGFNAPNTKLSTAVSKVEENLIKEKYQGYCSEI"
     gene            2901..8111
                     /locus_tag="KR231_002463"
     CDS             2901..8111
                     /locus_tag="KR231_002463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosome-binding GTPase"
                     /protein_id="HBH0004830.1"
                     /translation="MANKLYSEIVNLLEEGRDELRKYDLKEKSILLFLGASGVGKSTC
                     INYLKGCVMEEKTDEETGQIYITAKDSAVEIGNGVYSKTLCPEVVDIANRDFSLCDCP
                     GFFDNRGAEYMIAGAMLVRETISTSSKVKGMVVILDYQSLLDSRHTLLIETGKNLKDM
                     LGDYAKYKENFFFLINKIPKTLIGNVTEEKIRNILEKAKEDLDSQEKDYDGCKELVYL
                     LNVALSDGVSIKLCNPLDKQPEKLLDEMKNLPETFEKTDLGLMLTASCKIEIQKAVDV
                     TYKDLEKLLVPYIESVKKGMEDSISILSSINSLKDKKIQLDKMYTDLCSRTNNMKEIM
                     EFVQELSYGDGVQKVNILEETRLLLELNSYCSETHIVGLSELLKSLLKNTLEDTLKDI
                     KYWIAEEEYREEEAKKLEDAEYRIEKIQSCTYIKSYEKENVLSIYIPIPKVNLSDLTK
                     IISGYQLNILSSIYMYGDCELKIDCNMEKEVFSGKNIVLLTEKLHIPEGTYSINVSGK
                     DAEKLVGESSIYDGMNGRNGNNAGTSGDIILSFKEIEKRGELKLYVDGGRGGNGQDGK
                     KGDTGITGEAGANAKIGSKKESKEFANVKGTKYYVVKAEKGKQGGTGGTGGNGGNAGL
                     GSKSGQVYLLGKAPLLKSAISKKDGNHGLAGKGGSGGAGGAGGLGGIRGIYEETIRYI
                     GTSPPMDNSDRNYYYFDRYVFNHALNQKQAADDGEKLNALYEEHKDWIISKREDSGSA
                     GAEGTAGHSGDALKEKELLKQEYSLSIDTFFYEFFERFGFSGIKGYRNLRLLCAVGIL
                     EADILELSHIYEIFHAVEKIEMQLNREILQKYYSFEKKNKAVLSLDDMNTKKEFYKEA
                     KEIYEYLINKLMQSDRIESFVGKNQNFSEWSMILFALEQKTAFYVQMIEESEIGGNRV
                     TDIRSLTDYLDKTLRELEQGKKDELKEGYFNTYKESILTQIESGNQQIEVLKNELENK
                     MLSVNAKMNLLIQEIIKMKEDEQEDIEELKKKQAKLEEQMKTQLILSGIQSALSLLTA
                     FSGVGQACLGAFDSAKSLKENLSAKEEEYKWTNRMVNFSDFKLDSDGMRFVLGEQLSE
                     DRKNALDKMTYNLAGVDEERRTKFDQIKEIIVKSIDDDNYADKADDIQRAKEGLSESE
                     YKEIYTKIQKKEIGMLEANYNNKQQKDKLAALEKSKQAIERQQKTSKIKNALSIGSSA
                     CSLINTAISGVNNCLNVKSSFESKIEVVKEAIKDKENNIKKLDELNTQMVEFKDKTLK
                     ESVIPFVEKFDSTVKNQDIFENEISKLKMKEVLTELSTKFGSLKMENSEEISIIFKKV
                     QDMMETQIIITDKIDKKKDNLAMGELIYQMSDSGNQMNEYQKKLIHQIELNQVRYLCQ
                     VEAAAFQLWTFPFGSNIVNILNRCHVGITEDENEVINQAKEQNRQIREFLDQDAYQWQ
                     KTDNHILKVALTGSLDGKSRVGFENTYSLYDCNEEEVKKLLTGDEISFEVPLNKNFDA
                     IKYVTMYANIPNLRRNILEDSLKVKVHIHLYDSGYFSLYDDKKDVYYQYVFPQNYINI
                     THGLDVKYNDSDSINSIWSSVEDKGIEKFKNAGLNSGRSPYSMAKISLKAHFNKKLSY
                     DSLTNEQKKKLESYFDKPSKYAWSDSIDILKSLGYIDFKGILSKSWYEIKKDIDSDGE
                     IMKHFSILQVDLLERIIYEQTSILKENIPNLTIELVGCGIYVESEFNYLKQNDLKCYE
                     ERLVENTIIG"
     gene            complement(8336..10435)
                     /locus_tag="KR231_002464"
     CDS             complement(8336..10435)
                     /locus_tag="KR231_002464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HBH0004831.1"
                     /translation="MNFYIKHEIRGRIRFDLQLGKLNNKQSDTLLYYLTSINGITKAK
                     VYDRTGDAVIYYNGEREYIIREITKFSFNNSKIENLVPEHTSRELNNYYRDKLANKLL
                     VKSISKIFFPKSLRFFLIGLHSIKYFKKGLSSLLNKKIEVSVLDATAIGISIFRKDIN
                     TAGSVMFLLGIGELLEEWTRKKSIDDLAQSMSLNIEKVWLRKGDTEILIPISEIKEGD
                     LVSVTMGNMIPLDGVIVSGEAMVNQASLTGESLAVNKKEGSYIYAGTVIEQGNIVMCV
                     KEKAGTTRFQKIVTMIEESEKLKSSVESKFEHLADTLVPYSFLGSILTYAITRNPIKS
                     LSILMVDFSCALKLSIPISVLSAMRECNNNNITVKGGKFLEGVACADTIVFDKTGTLT
                     KAQPTVSDIITFQNYNKEDMLRLAACLEEHFPHSIANAVVYEAEKQGLSHKEMHTEVE
                     YIIAHGISTKVDDKKVVIGSKHFVFEDEKCTIPDGEEDKYNNLSDEYSHLFMAISGKL
                     SAVICINDPLRKEAKYVISNLRECGIKKIVMMTGDSEKTAKSIASKVGVDEYYSEVLP
                     EDKANFVKSEKLKGRKVIMIGDGINDSPAISESDVGIAMSEGAEIAREISDITISADN
                     LNNLIVLKQISNKLMKRVDLSSKFIIGFNLGLILLGVGGFVRPSTSAFLHNASTVGIS
                     LNSMTNLLENTNTYNYH"
     gene            complement(10478..10873)
                     /locus_tag="KR231_002465"
     CDS             complement(10478..10873)
                     /locus_tag="KR231_002465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429546.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0004832.1"
                     /translation="MNILKMKKTGIFLGGVLFGTVGVKILSSDCVKKTCTRATAGALK
                     VKDSVLETTTKIQENVEDILAEAKEINEQEDLSTSKVNVVQDTLKCEQEVLKTETIKT
                     VEDTNSNSIKCEEIKDNVIEEKNSTCTTE"
     gene            11813..12001
                     /locus_tag="KR231_002466"
     CDS             11813..12001
                     /locus_tag="KR231_002466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0004833.1"
                     /translation="MNKNNNLVIICMFIGMILGMAIGCAIGISKGNVGITMCYGLIFG
                     MIIGICIGTVIKNSNKKE"
     gene            complement(12186..12626)
                     /locus_tag="KR231_002467"
     CDS             complement(12186..12626)
                     /locus_tag="KR231_002467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3788 domain-containing protein"
                     /protein_id="HBH0004834.1"
                     /translation="MYERMLDKSNKPCLSQIIEYIGKDGYARLCKLETYLKTQYNLSR
                     ELRFPFGNNYGWGYKYSHKSFHLFYAFFEKGAFTVLIQIGDKQVPAVEKTLVALTPKA
                     KELWVTRYPCGNNGGWIKYRILEDADLLDIIQYIRAKKSPPKQN"
     gene            12981..14294
                     /locus_tag="KR231_002468"
     CDS             12981..14294
                     /locus_tag="KR231_002468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3440 domain-containing protein"
                     /protein_id="HBH0004835.1"
                     /translation="MDKRYLESDVFEAFQERLSYLFNEFDYIYVSFSGGKDSGLLLNL
                     VLDYKRKNNISSKIGVFHQDFEAQYSLTTEYVEKVFEDNIEDIEPYWVCLPMATRTAV
                     GNYEMYWYPWDDEKEELWVREMPVKEYIINQKNNPFTYYKYKMRQESLAKQFGRWIRD
                     IHEGAKVVCLLGTRAAESLQRYCSIVNKQHGYKGKCWITKEFKNVWTASPIYDWEIED
                     IWLAHYKFDYDYNKIYDLFYKAGVAPRKMRVASPFNDSAKESLNLYRILDPDVWVKLV
                     ARVQGVNFTSIYGKTKAMGYRSVKLPYGHTWKSFTYFLLDTLPENIRNSYIKKFSTSI
                     EFWQNTGGGLSEIVIRELLRKGYKIELNGVSNHTKDKKSRVIFLDDIPDDTDDIKFTK
                     DIPSWKRMCYCILKNDHMCRFMGFGPTKEQRIRTEYIKKKYEKIH"
     gene            14312..14848
                     /locus_tag="KR231_002469"
     CDS             14312..14848
                     /locus_tag="KR231_002469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418051.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParB-like nuclease domain-containing protein"
                     /protein_id="HBH0004836.1"
                     /translation="MEYKSPVYGIIAVPIEKIESNDYNPNAVAPPEMQLLYKSIKEDG
                     YTMPIVCYYNEEKDKYIIVDGFHRYRVMLENEDIYDRENGLLPVSVIDKSLDERMAST
                     IRHNRARGSHNVDLMSKIITELCEIGKSDEWISKHLGMEVDEILRLKQITGLAYLFKD
                     KEFGNAWIPFGSDIEEEN"
     gene            15364..15585
                     /locus_tag="KR231_002470"
     CDS             15364..15585
                     /locus_tag="KR231_002470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="spore coat associated protein CotJA"
                     /protein_id="HBH0004837.1"
                     /translation="MGYLKEDKQDYCCEFARPYINRQIYDDTYNPKTALKRGTLFPEL
                     DLIESNNYNDWLYANPKNRVRAKKGGNMY"
     gene            15585..15848
                     /locus_tag="KR231_002471"
     CDS             15585..15848
                     /locus_tag="KR231_002471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="spore coat protein CotJB"
                     /protein_id="HBH0004838.1"
                     /translation="MSLNRRELLERISEYQFACIELNLYLDNNPRDKKALDSYNRYCD
                     KFTQAVCDYESKYGALTNFGYESSEYPWSWISEPWPWDKSFYK"
     gene            15910..16482
                     /locus_tag="KR231_002472"
     CDS             15910..16482
                     /locus_tag="KR231_002472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="manganese catalase family protein"
                     /protein_id="HBH0004839.1"
                     /translation="MWIYQKTLEHPVNIRQADPRMAKYIMTQLGGPNGELAAATRYLQ
                     QRYTMPTGKSRALLTDIGTEEMAHVEIISSVLYQLIGNCTPEELKAAGLGSNYANFGH
                     GLQPVDSNGVNFTTSYINVFGDSVTDLHEDMAAEQKALATYYQLINLTDDPDLKDILR
                     FLGEREVVHYQRFGEALMDVYEFTECKHQF"
     gene            complement(17236..17586)
                     /locus_tag="KR231_002473"
                     /pseudo
     CDS             complement(17236..17586)
                     /locus_tag="KR231_002473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729451.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            17903..18436
                     /locus_tag="KR231_002474"
     CDS             17903..18436
                     /locus_tag="KR231_002474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylated-DNA--[protein]-cysteine
                     S-methyltransferase"
                     /protein_id="HBH0004840.1"
                     /translation="MQYISYYHSPIGNILLASDNIGLTGLWFENQKYYAYNLDQEHQE
                     KELPIFEQTKKWLDIYFSGKEPDFTPSLHMVGTPFQTTVWKILQQIPYGKTITYGEIA
                     YKVAQQKGISKMSAQAIGGAVGHNGISIIIPCHRVVGTNGSLTGYAGGINRKIKLLSL
                     EKVSVQHYFIPKKGSAL"
     gene            18662..18841
                     /locus_tag="KR231_002475"
     CDS             18662..18841
                     /locus_tag="KR231_002475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HBH0004841.1"
                     /translation="MLQTGKQGADKKYLDNMFFVKGYVEELLFLDNNYNIVFSCIVFH
                     HCTNVQNIFCIFWKW"
     gene            complement(19449..20066)
                     /locus_tag="KR231_002476"
     CDS             complement(19449..20066)
                     /locus_tag="KR231_002476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid stabilization protein"
                     /protein_id="HBH0004842.1"
                     /translation="MDEKILELLQEMQGSISGIEGTISDMQSNINGIEGTISDMQSNI
                     NGIEGTISSMQGNINGIENTISGMQGTIGDMQGSISGMNGTISDMQGSISSMDGTINS
                     MQDSITDMQVEIKEVNSKLDNMEPDIKDLKTGQVETSSRLDTIQSDVTEIKSDVKINR
                     NTLDTVIKHTSSLVKDTSDIKNDLNNIEIVTSKNSNDIAKLKSVK"
     gene            20532..20945
                     /locus_tag="KR231_002477"
     CDS             20532..20945
                     /locus_tag="KR231_002477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003507530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3795 domain-containing protein"
                     /protein_id="HBH0004843.1"
                     /translation="MKMPKESIDTIMFAPCGMNCMVCYKHCYHKKPCAGCLNGDTGKP
                     EHCRKCKIKDCVCQKGLFYCFECFNFPCKLIKNLEKSYNKRYQASLMENSKFVQQYGL
                     EKFMQKQKERYTCSKCGGIISIHDRECSECQEKVK"
     gene            21018..21554
                     /locus_tag="KR231_002478"
     CDS             21018..21554
                     /locus_tag="KR231_002478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GrpB family protein"
                     /protein_id="HBH0004844.1"
                     /translation="MIGLKCGMVKLLEHQMIWDKSAKDVIILLKSIWDKTAIDIQHIG
                     STSIPSISAKPIIDIVVGVASLEEAKLYLERLEQCGIVFRGQDVPKQLLFAMGDFEKN
                     TRTHHIHVVEWNGVAWNNYINFRDYLNTFTDKAKLYDSHKQKLALQFEDNRKIYTQRK
                     QELINILLEEARLWRINT"
     gene            21714..22376
                     /locus_tag="KR231_002479"
                     /pseudo
     CDS             21714..22376
                     /locus_tag="KR231_002479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016440163.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="chloride channel protein"
     gene            22922..23041
                     /locus_tag="KR231_002480"
                     /pseudo
     CDS             22922..23041
                     /locus_tag="KR231_002480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888399.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            23168..24070
                     /locus_tag="KR231_002481"
     CDS             23168..24070
                     /locus_tag="KR231_002481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895617.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chloride channel protein"
                     /protein_id="HBH0004845.1"
                     /translation="MLPQDYYGLIVILGVILGVMGAFYNWFTLYVQSLYKKIPKIGTF
                     GKLLIPFIMAGILGLVMPDVLGSGHNLVEELTSHEYIFGMVVLIFVIRFIFSAVSFGS
                     GAPGGIFFPLLVLGAFIGGIFGMVGVKVFGMNPDYVNNFVLLAMAGYFTAIVRAPLTG
                     IILIFEMTGSVSQMLSLSVISIVAYIVATLMKSKPIYESLLERLLEKNGEPVHKERGE
                     KILDQFSVMFGSPVANKAIQDVQWPENCLLVAIQRGGEEIIPRGKTILRPSDVIVTMT
                     DERDSGAVYDKMENLCKEHTSHIF"
     gene            24682..25695
                     /locus_tag="KR231_002482"
     CDS             24682..25695
                     /locus_tag="KR231_002482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M56 family metallopeptidase"
                     /protein_id="HBH0004846.1"
                     /translation="MVSSFLNDIFRTILVSCIFIVILLVFRITLFKIFSKKFNYYIWL
                     IVIIKLSLPFMNYTFIFNESKYNGNINKISLGNFNSISIVYSTVLVSVWIAITIFYLV
                     YTLLKYIKLKNMINDLSYDVEDDKIKNLYENLLKELKINKKIRLKYSYEVESPVFFNS
                     CVILPPSDYTLKELNWIFRHELMHFKSKDLYIKYLVIFLKCVYWFNPFVYIMEKFIDL
                     DCEFYCDERVLKNCTIEEKQDYALTIISAMRKGSNSSNKFVAGLHKESDIKKRVFSMF
                     NEKYRNGILIAVILCLLSSITYFKIDLITTKSIFYPLSKQTPIENRTNSKPTYQINVY
                     IDN"
     gene            26051..26620
                     /locus_tag="KR231_002483"
     CDS             26051..26620
                     /locus_tag="KR231_002483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GrpB family protein"
                     /protein_id="HBH0004847.1"
                     /translation="MKKKLEDMTLEELWNLFPIFLTTHKECWKNWFKEEQYRLTGILP
                     MQKIVRISHIGSTSVSTIYAKPIVDILIEIIPDYNMKDIKDLIESNGYICMSESSSRL
                     SLNKGYTVDGFEERVFHLHIRYVGDNDELFFRDYLIDHPDVAKEYEKLKLDLWKKYEH
                     NRDAYTDSKLDFVREFTEKAKVLYFNRYN"
     gene            complement(26956..28293)
                     /locus_tag="KR231_002484"
     CDS             complement(26956..28293)
                     /locus_tag="KR231_002484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HBH0004848.1"
                     /translation="MGTYSLISTSINFILILINIFIAFFLYTLTSYFIDFRNHWIFKI
                     ILILGYSIISQMIIWLSDPVNILFTLFGYFILLIICSKSKLIPIISVVMIFYPIIIGL
                     NFLFINNPIYEELIHSKEYILILSIVQIISALIKLLFWFLIHIFLKNRLVNIKQYLSN
                     KIWIFIDMVCISSFLSILIAIILPPTNLIPMGSNKNIILGNLPYGTYLIILSAILANI
                     GVILLLQPLIENVKMKIEKQANHLKEKYYNLLENQQIQIRKMRHDMNNHFQMIESYLE
                     IEDIAGAKKYFNQLKIGIGTLSGKQFCKNQALNSILNLRHTSLEENGVDVHFNIDIDN
                     HLGIEPIDLCTIFSNSLDNAIEASLKIPDLSNRKVVLKARCEKEYFSYLLTNNKVNPI
                     NRKQELFISDKKDSNSHGYGIENIREIVNKYNGKLDISYTENEFSLFLYIRLF"
BASE COUNT        10688 a         3187 c         4947 g         9694 t
ORIGIN      
        1 ataaaatatt caagctggta taggtgtaaa acttaagcag tagtatagga atgtttaaat
       61 taatggtaca aatataatta aaaatctata tgtaataacc acaggaaaat aatggacata
      121 taatataaaa aacaactgta ttacataaaa tacaataaaa taagcgcatt aaataaaata
      181 actgtgttga taaagattat attatacaac acagttattt taataaacaa agaagaataa
      241 ttattgagtg aaaatacaaa tttagtgaaa atgcaaattt attaaaaata aaaaataaaa
      301 aacaaattta aatatagtat aaaaactttg caatctactt aagggattaa actttattta
      361 aataaaatat ataaccaagg gggaaaataa atgccagaaa ataacaatca acttttagaa
      421 gaaataacac tcttattaaa tgaaggaaaa gtagcaataa ataaggctga aaatcaaaat
      481 ttaattctaa ttcttggtgg gacaggatgt ggcaaaagta ctgcaattaa ctatcttgca
      541 ggatgtgtaa tgatggaagt agaagatgaa gatactggta tatcatatat tgattgctta
      601 gaccctgtgg cagagattgg ttcaggagct gtttctcaaa ctttataccc gaacattgta
      661 aatatgagaa aaccaataga aggaatggat gcaaaattat gtgatactgc aggttttagc
      721 gacaataggg gagtagccca tgatattagt gcagcagttt cattaggtga agtatttaaa
      781 aattctgcat ctatatgtgc agtaattgta ttgataccag aagcagatat attagattct
      841 agacttacaa aagtactaga cctgttccaa cagttaaata tgtgtcttca taaagaaaat
      901 tttaagggta gtataacttt tttcatttca aaaagtttct taggaagaac agaaaaacaa
      961 atatataatg ttataaaaag aaaatatgaa caattatgcg aaaatttaga cagtaatata
     1021 gaggaaaaag cttggttatt tgaagaattg ctaaaagata atggaaaaaa tattcatctt
     1081 tgtaagccac ttgcatcaga tgagagggaa ggcttattaa agcaagtact agaattagat
     1141 gaagttaaag ataagacatc agcattccaa tatccaatta gtgcagatgc aagattagtt
     1201 ttagatacgt tgataaaaga aattcaaaac aatatcgtat ctagcctaga agattatgtt
     1261 aaggcgtata cagaagattt tatcaatatt attggaagta taacaatgat tcaagaaata
     1321 gcaaaatatg atgaggttgt aaaagtattt aaaaactggt tggaaagtac aacaagtctt
     1381 actatagaga gatttatcaa cgtattagcc aaacaaagtg gattattctt acaagatagt
     1441 tgcatgaaat tacaaaataa gataaaagga aacttagata taattgatgc tttaagtaaa
     1501 tatacagaac atggaactgg ggaaatttta ttaccttctg tacatatgga atttattata
     1561 gaaaaggcaa gtaagaagat aatggaacaa aacttcatta taataagaaa gaatttagaa
     1621 aaagttttag tttcttatga agtgcaaaaa caggtattta cattaccaaa tagagaaaaa
     1681 ttaatggaag ttgcaaataa aaaggattat gtatatagtg taagtgattt taattcaatt
     1741 ttgacaaatg ttacagttac acaaaatgaa gagttagaag acagtataac aagattaagt
     1801 gcatatggag aagaaggtaa tgagataatt agagaattta ttggtaaata cattttaaat
     1861 ccatttatag taaaaacaat taatattaat gataagaaag gtattgaaat aagagcatta
     1921 attccaaact tagtaattag cagtgtattg gaatatttca aaaatagaaa agtagatgac
     1981 aatgtttcta catttatgtt ctttgctaaa gatactattt atatggatga taaccttgga
     2041 atgaactttg catcagagaa aaatattatt cttgcttcta acaatcttga tgtaggtagt
     2101 aatgtaaaaa ttaatgtaag tggaaagagc ggagaacttg tagataattc tatgtatggg
     2161 aaaaatggtg aagatggtag agatgcaggt aatatttact tatatattaa agaagaaatt
     2221 agaaattatc gtctaacact gattgcaaat ggaggaaatg gttctaaagg aatagatggg
     2281 gaaaatggtg aaacaggagc ttctggaagt aatggagctg atgcaggata tacaagttat
     2341 ttccacggac agatgtttaa agggtatttt gaaaaaggta caagtggcaa aaaaggtgaa
     2401 aaaggtggag ctggtggaaa tgctggaaga ggtggaaatg ctggtaagaa aggtaatatt
     2461 tacttcattt cagattcaga ggaacaaaaa aatagaataa ttaatcattg tgatataaca
     2521 gtgaaagatg gagaagcagg tccaaatggt agaccaggtt taggtggata tggaggaagt
     2581 ggtggctatc acggatataa tacactttca ttttctccaa gtggtataga taagactgta
     2641 tactatacag gatattttac aagttgggat tataagttag atagtataat taaatatcat
     2701 atagaattta gtggtggaag ctggaatgaa ggtaaaacag gaccagcaag agaatacgct
     2761 gaatatggag atagaggaga caatggagga tttaatgctc caaacactaa gttatcaaca
     2821 gctgtttcaa aggtagaaga gaatcttatt aaagaaaaat atcaaggcta ttgttccgaa
     2881 atatagaaag ggatggatgt atggcaaata aactttatag tgaaatcgta aaccttttgg
     2941 aagaaggaag agacgagctt agaaaatatg acttaaaaga aaagtcaatt ttgttattct
     3001 taggtgcttc aggcgttgga aagagtactt gtataaatta tttaaaaggc tgtgtgatgg
     3061 aagaaaaaac ggatgaagag actggacaaa tatatataac tgcaaaagat tcagctgtcg
     3121 aaattggaaa tggtgtatat tctaagactt tatgtccaga agttgtagat attgcaaata
     3181 gagatttttc attatgtgat tgcccaggtt tttttgataa ccgtggagca gagtatatga
     3241 ttgctggtgc tatgcttgta agggaaacta tttccacatc ttcaaaggta aaagggatgg
     3301 tagttatttt agactatcaa tccctactgg actctagaca tacattattg atagaaacag
     3361 gcaaaaattt gaaagatatg cttggtgatt atgcaaagta taaagaaaat ttcttctttc
     3421 ttatcaataa aatacctaaa acactaattg gtaatgtaac agaagaaaaa ataagaaata
     3481 tattggaaaa agcaaaagaa gacctagata gtcaagagaa agattacgac ggttgtaagg
     3541 aattagtgta cttattaaat gtagcattat cagatggtgt atctattaaa ttatgtaatc
     3601 cactagataa acagccagaa aagttgttgg atgaaatgaa aaatctacct gaaacatttg
     3661 aaaaaacaga tttggggttg atgcttactg cttcttgtaa aatagaaata caaaaagctg
     3721 ttgatgtaac ctataaagac ctagaaaaac ttttagttcc ttatatagaa agtgttaaaa
     3781 aaggtatgga agattctatt tccattctat cttctataaa tagtctaaaa gataaaaaga
     3841 ttcaattaga taagatgtat acagatttat gtagtaggac taataatatg aaagagatta
     3901 tggagtttgt acaagaactt tcatatggtg atggcgtaca gaaagtgaat atattagaag
     3961 aaacacgtct tcttttagag ttaaatagtt actgtagtga gactcatatt gttggtctaa
     4021 gtgagttgtt aaaatcattg ctaaaaaata ctttagaaga tacattaaaa gatatcaaat
     4081 attggatagc agaagaagaa tatagggaag aagaagccaa aaagcttgaa gatgcagagt
     4141 ataggataga gaagattcaa agttgtacat atataaaatc atatgagaaa gaaaatgtac
     4201 tttctatata tattcctata cctaaagtga atttatcgga tttgactaaa ataatatctg
     4261 gttatcaact taatattttg tcatctatat atatgtatgg agattgtgag ttgaaaattg
     4321 actgtaatat ggagaaagaa gtcttctcag gtaagaatat tgtactactt acagaaaaat
     4381 tacatatacc agaagggact tattcaatca acgtatctgg taaggatgca gaaaaattgg
     4441 ttggagaaag ttctatttac gacggaatga atggaagaaa tggcaataat gcaggtactt
     4501 caggtgatat catattatct tttaaagaaa tagaaaaaag aggagaactt aaactttacg
     4561 tagatggtgg acgtggtgga aatggacaag atggaaaaaa aggagataca gggataactg
     4621 gagaagctgg ggcaaatgct aaaataggtt ctaaaaaaga gtcaaaagaa tttgctaatg
     4681 ttaaaggtac aaaatactat gtggtaaaag cagaaaaagg aaaacaaggt ggaactggag
     4741 gcacaggagg taatggtgga aatgcaggtc ttggaagcaa gtctggacag gtttatctcc
     4801 ttggaaaagc tcctttatta aaaagtgcta taagtaaaaa agatggaaat catggtttag
     4861 caggaaaagg aggctctgga ggagctggtg gtgcaggagg tcttggtgga attagaggta
     4921 tatatgaaga aacaataaga tatataggta cctctcctcc aatggataat agtgatagaa
     4981 actactatta ttttgataga tatgtgttta atcatgcttt aaatcagaag caagcagcag
     5041 atgatggaga gaaattaaat gctctttatg aagaacataa ggactggata attagcaaac
     5101 gtgaagattc aggttcagcc ggagcagagg gaacagccgg tcactctgga gatgcactaa
     5161 aagaaaagga attgttaaag caggagtatt ctttgtcaat agatacattc ttctatgaat
     5221 ttttcgagag atttggtttt tctggaatta aaggttatag aaatcttaga ctgttgtgtg
     5281 cagtaggaat tttagaagct gatattttag aactttcaca tatttatgaa atttttcatg
     5341 cagttgagaa aatagagatg caattaaata gagaaatact tcagaagtac tatagttttg
     5401 agaagaaaaa taaagcagta ctttctctgg atgatatgaa tacaaagaaa gaattttata
     5461 aagaagcaaa ggaaatctat gaatacctta taaataaatt gatgcagtct gatagaatag
     5521 aatcttttgt aggaaaaaat cagaatttta gcgaatggag tatgatttta tttgcacttg
     5581 agcagaagac agcattttat gtgcagatga ttgaagaaag tgaaattgga ggaaatcgtg
     5641 ttacagatat tcgttctttg acagattatc tggataagac cttaagagaa ttggaacaag
     5701 ggaagaaaga tgagttaaaa gaaggatatt tcaatacata taaggaaagt atcctaactc
     5761 aaattgaatc tggaaatcaa caaatagagg ttttaaaaaa tgaacttgag aataaaatgc
     5821 tttctgttaa tgcaaaaatg aacctgttga ttcaagaaat tataaagatg aaagaagatg
     5881 aacaagaaga catagaggaa ctaaaaaaga aacaggcaaa acttgaggaa caaatgaaaa
     5941 cacagttaat tctttctgga atacaaagcg cattgagttt actgactgca tttagtggtg
     6001 ttggtcaagc ttgtctaggg gcatttgaca gtgcaaaatc tttgaaggaa aatctttcag
     6061 ctaaagaaga ggaatacaaa tggactaaca ggatggttaa tttttcagat tttaaattgg
     6121 attctgatgg tatgagattt gtacttggag aacagctaag tgaagataga aaaaatgctt
     6181 tagataaaat gacttataat ttggcaggtg ttgatgaaga aagaagaact aaatttgacc
     6241 aaattaagga gattatagtt aagtctatag atgatgataa ttatgcagac aaagctgacg
     6301 atattcaaag agcaaaagag gggttaagtg aaagcgagta taaggaaatt tacacaaaaa
     6361 tccagaaaaa agaaataggt atgttggagg caaattacaa taataaacag caaaaagata
     6421 agttagctgc actagagaaa agtaaacaag ctattgaaag acagcaaaag acatctaaaa
     6481 ttaaaaatgc attgagtatt ggaagttctg cttgttctct tataaatact gcgattagtg
     6541 gtgttaataa ttgtcttaat gtaaaatcta gttttgagag taaaatagag gtagttaaag
     6601 aggcaattaa agataaagaa aataatatta agaaattaga tgaattgaat actcaaatgg
     6661 tggaatttaa agataaaact ttgaaagaat ctgttatacc atttgtagaa aaattcgata
     6721 gtacagttaa aaatcaagat atttttgaaa atgagataag taaattaaag atgaaggaag
     6781 ttttaactga attaagcaca aagtttggaa gcttaaaaat ggaaaattca gaggagattt
     6841 ctataatatt taaaaaagta caggatatga tggaaactca aattatcatt actgataaga
     6901 ttgataagaa aaaagataat cttgcaatgg gagaattgat ttatcaaatg tcagatagtg
     6961 gtaatcagat gaatgaatat cagaaaaaac ttatccatca aattgaatta aatcaggtta
     7021 gatacttgtg tcaggttgag gcagcagctt ttcaactatg gacattccca tttggaagca
     7081 atatagtaaa tatcttaaat agatgccatg tagggattac agaagatgaa aacgaggtta
     7141 taaatcaggc gaaagagcaa aatagacaga ttagagagtt tcttgaccaa gatgcttacc
     7201 aatggcaaaa aacagataac catattttga aggtagcatt aacaggcagt ttagatggga
     7261 aatcacgtgt gggatttgaa aatacatatt ctctatatga ttgtaatgaa gaagaagtga
     7321 aaaagctttt gacaggagat gaaattagtt ttgaagttcc attaaataaa aactttgatg
     7381 ccataaaata tgtaaccatg tatgcaaata tcccgaacct tagacgaaat attttagagg
     7441 atagtttaaa agtaaaggtg catattcatt tatatgatag tggatacttc tctctatatg
     7501 atgataaaaa agatgtctat tatcaatatg tatttccaca aaactatata aatattacac
     7561 atggtcttga tgttaaatac aatgattcag attcaataaa ctcaatatgg tcttcagtag
     7621 aagataaagg aattgaaaag ttcaaaaatg caggattaaa ctctggtaga agtccatatt
     7681 ctatggctaa gatttctttg aaggcacatt ttaataagaa gctttcttat gattcactta
     7741 caaatgagca gaagaagaaa ctagagtcat actttgataa acctagtaag tatgcatgga
     7801 gcgatagtat agatatattg aagagtctag ggtatattga ttttaaggga attttgtcaa
     7861 agagttggta tgaaatcaag aaagatatag atagtgatgg ggagattatg aagcattttt
     7921 ctatattaca agttgattta ttggaaagaa ttatttatga gcagactagt atactaaagg
     7981 aaaatatacc taatttgaca attgaattgg taggctgtgg tatttatgta gagtctgaat
     8041 ttaattatct aaagcaaaat gatttaaaat gctatgaaga aagattggtt gaaaatacaa
     8101 ttattggttg aaaatataat taatatataa attttaaaga aatttacaaa aggggatgtt
     8161 tcaaaatgaa aatttgaatc atctcctttt ttgtaaaaaa tagaaataag ttgagtttaa
     8221 aatttgtaaa gtatgcttta tataattttg attagaaaaa agctaatttt aagacatatt
     8281 tttttaaaaa gatgaattat aaatttttta tatcatatgt tttatgtaat ggagattaat
     8341 ggtagttata agtattggtg ttttccaata aatttgtcat actgtttaaa cttattccga
     8401 cagtagatgc gttgtgtaaa aaggcagatg tacttggtct aacaaatcca cctacaccaa
     8461 gtaaaatcaa acctaaatta aagccgataa taaacttaga acttaaatca actcttttca
     8521 taagcttatt actaatctgc tttaaaacga ttaaattatt caaattatct gctgatatgg
     8581 taatatctga aatctctctt gctatttcag caccttcact cattgcaatt ccgacatctg
     8641 attctgaaat agcaggagaa tcattgattc catcaccaat cataattact ttgcgacctt
     8701 tgagtttttc acttttaaca aaattggctt tgtcttctgg taagacttct gaataatatt
     8761 catcaacacc aactttactt gctatagatt tagctgtttt ttcgctatct ccagtcatca
     8821 tcacaatctt ttttattccg cattctctta aatttgaaat tacatatttt gcttcttttc
     8881 gtaaagggtc atttatgcaa ataactgctg ataatttacc tgatattgcc ataaataggt
     8941 gtgaatactc atctgataga ttattgtact tatcctcctc accgtctggg atagtacact
     9001 tctcatcttc aaatacaaaa tgtttgctac ctattacaac ctttttatca tcaacttttg
     9061 ttgaaatgcc atgagcaata atatattcta cttctgtatg catttctttg tgactaagcc
     9121 cttgtttttc agcttcataa actactgcat ttgctatgga gtgtgggaag tgttcttcta
     9181 agcaagctgc aagtcttaac atatcctcct tattataatt ttggaatgta attatatctg
     9241 aaacagttgg ttgagctttt gttaatgtgc ctgtcttatc aaatacaata gtatctgcac
     9301 atgcaacacc ttcaagaaat tttccacctt ttacagtaat gttgttattg ttacattctc
     9361 tcatggctga tagtactgaa atagggatag agagttttaa tgcacaagag aaatctacca
     9421 ttaatataga gagtgatttt atagggtttc tagtaattgc ataggttaat atacttccta
     9481 aaaagctgta tggaactaat gtatctgcta gatgttcaaa tttactctct acagaagatt
     9541 ttagtttttc agattcctca atcatagtta ctattttctg gaatctagta gtaccagctt
     9601 tttccttgac gcacataaca atattgcctt gctctattac agttccagca tatatgtaag
     9661 atccttcttt tttgttaact gcaagggatt cacctgtaag tgatgcctga ttgaccattg
     9721 cttctcctga tactataact ccatccaatg gaatcatatt tcccatagtt acacttacta
     9781 aatctccttc ctttatctct gaaattggaa ttaggatttc agtgtcacct tttcttaacc
     9841 atactttttc aatgtttagt gacatacttt gagccaagtc gtctatagat ttttttctag
     9901 tccattcttc taatagttca ccgataccaa gaagaaacat aactgaacca gccgtattga
     9961 tatcttttct aaaaatagaa atacctatag cagtggcatc taaaacagaa acttctattt
    10021 ttttatttag cagggaagag agaccttttt taaaatattt tatagaatga agtccaatta
    10081 aaaaaaatct taaggacttt ggaaaaaata ttttggagat acttttgact agcagtttat
    10141 ttgctaattt gtctctataa taattgttta attccctgct ggtatgttca ggaactaggt
    10201 tttctatttt gctattgtta aaactgaatt tagtgatttc tcttattatg tattctcttt
    10261 caccattgta ataaatgact gcatcaccag ttctatcgta aacttttgct ttggtaatac
    10321 catttataga agttaaataa tataagagag tatcggactg cttgttgttt aatttgccaa
    10381 gttgtaagtc aaagcgtata cgacctctta tttcgtgttt tatataaaaa ttcaatttac
    10441 ttcctcctga tattattaat cataataatc attaaatcta ttctgttgta caagtactat
    10501 ttttttcttc aattacgtta tctttgattt cttcacattt aatgctatta gaattagtat
    10561 cttctacagt ttttatagtt tcagttttaa gaacttcttg ttcgcattta agagtatctt
    10621 gtacaacgtt taccttagat gtagataagt cttcttgctc gttgatttct tttgcttcag
    10681 ctaaaatatc ttctacattt tcttgaattt tcgtagttgt ttcaagaaca gaatctttaa
    10741 ctttcaatgc tcctgctgtt gcacgagtgc aagttttttt aacacaatca cttgaaagta
    10801 tcttaacacc tacagtacca aaaagtactc ctcctaaaaa tatccctgtt tttttcattt
    10861 ttaaaatatt cattttacat tatcctttca tttagttaga ttttgtttgt acttatgtat
    10921 aaggtaacaa atgttaaaaa tagagtatgt tttacaaaat tagtttagag agtttagtaa
    10981 ttttatttga tttatattag taaatttaca tgaattttac atatgtagtt tatatagttg
    11041 aaataattct tatatagctt atatatgcaa tttatatatc tagcttatat agttgaggta
    11101 atactttatc tagcttatat aatttatata aatttataac cgaatactac acagtttata
    11161 cataacatat tgtttgagct tatctagttc atataaattt ataacttata taaatttttt
    11221 gtactttgta ttttagaaag ttcttgatat ttagtccaaa aaatttaaaa tacagtaaaa
    11281 gtaataattg ttattaatag atttgtaaaa tcatatgaca tttattacca tttatgcaat
    11341 taagtatagc atgtgcgaat ggtattttca acagaaaatg ataatttata tcaattaatt
    11401 tagttgattt gtaatagagc atcaaaaagt atacttattt atatatggga atgaaaggca
    11461 aagttttatt tttttcaatt aaagtgtgtt agatatatta ttataaatga acattatttt
    11521 aagtataata atgattagta gggagtgttt atgatgtata aatgaataaa aatatagttt
    11581 atgattgtaa atattatgta aatataaaag ttacttaaat ggttttagga aattgatatt
    11641 attgcgtctg ggagattgta cttacttcaa aaagaggagg ttatgacaag aaatgtgttg
    11701 tttgacattt atacaagcag atattagaat gaaagaaagt taatttatat ttctttgttt
    11761 taagctaaga aggcgagcta ggcaatttaa aatatattga atggagaaaa ctatgaataa
    11821 aaacaacaat ttagttatta tatgtatgtt tataggcatg atacttggaa tggctatagg
    11881 ttgtgctata ggtatttcta aaggaaatgt aggtatcaca atgtgttatg gtctaatttt
    11941 tggaatgata attggcatat gtatagggac tgttatcaaa aattctaata aaaaagaata
    12001 aattaatttt gatttactag gatgtctagt tatgatttat ttatgataaa actttttaat
    12061 tatctgtaaa aagtagaata agacatacta aataagttat actaatagat attttttata
    12121 ttattttttt tatatggaaa gaatggaatt tatatacact atatttaaat cacaaaaaat
    12181 aaaagttaat tttgtttagg tggagatttt tttgctctta tatattgaat aatatcaagt
    12241 aagtctgcat cttctaaaat acgatactta atccagcctc cattattgcc acaaggataa
    12301 cgagtgaccc agagctcttt agcttttggt gtcaaagcta ccaacgtttt ttctactgct
    12361 ggaacttgct tgtcacctat ctgaatcaga acagtaaatg cacctttttc aaaaaaagca
    12421 taaaataaat gaaaagattt atggctatat ttgtaacccc aaccataatt gtttccaaaa
    12481 ggaaatcgaa gttctcttga taaattatat tgagttttca agtaagtttc caacttacac
    12541 aatcgtgcat atccatcttt acctatatat tctattattt gagacaaaca gggtttattg
    12601 cttttatcaa gcatacgttc atacattaga atttacctcc atttttactt ttaattatag
    12661 caaagtaatt atgacaacag tatgtcaagt ttttatgcat tattcaagtt tttatgtatt
    12721 attatactaa tacgtagaaa tataaagtaa ttagttttag ctaatagaaa aatatgatat
    12781 ttatatatat tggaaaaaaa tgtaaaataa tgataaaata tagtttataa tacaaaagta
    12841 taattacatt ataattatat gtagttagtt ggatttgtgt atttaaataa tgtataattt
    12901 atgctgatta ctgctaaaaa agcataataa tattgcattg taaggtttta taaacttcta
    12961 attgaaaggg gataattcaa atggataaga gatatttaga atccgatgta tttgaagctt
    13021 ttcaagaaag actttcttat ctttttaatg aatttgatta tatctatgta tcttttagcg
    13081 gaggaaaaga tagtggttta ctgctaaatt tagttttgga ttataagaga aagaataata
    13141 taagttccaa aataggagta tttcatcaag attttgaggc tcaatatagt ttgactactg
    13201 aatatgttga aaaagtattt gaagataata ttgaagatat tgaaccatat tgggtgtgtt
    13261 taccaatggc tacaagaact gctgtaggaa attatgaaat gtattggtat ccatgggatg
    13321 atgagaaaga agagttatgg gtaagggaaa tgccagtcaa agaatacata ataaatcaaa
    13381 aaaataatcc ttttacttat tataaatata aaatgagaca agaaagtttg gcaaaacaat
    13441 ttggtagatg gattagagat atacatgaag gtgcaaaagt tgtttgctta ttaggaacac
    13501 gagcagcaga atctctacaa cgttattgtt ctattgtgaa taaacagcat ggatataaag
    13561 gaaagtgctg gataactaag gaatttaaaa atgtctggac ggcatctcct atatatgatt
    13621 gggaaataga agatatatgg ttagcacact ataaatttga ctatgactat aataaaattt
    13681 atgacttatt ctataaagct ggagtagctc caagaaaaat gagagtggca tcacctttta
    13741 atgattcagc aaaagagagt ttaaatttat acagaatatt ggacccagat gtatgggtga
    13801 aattggttgc tagagtacaa ggagttaatt ttacttctat ttatggcaaa acaaaagcta
    13861 tgggatatcg tagtgttaaa ttgccatatg gacacacatg gaaaagtttc acatattttt
    13921 tgcttgatac cttacctgaa aatataagga atagctatat taaaaaattt tcaacatcta
    13981 ttgagttttg gcagaataca ggtggtggtt tgtcagaaat agttatacgt gaattgttga
    14041 gaaaaggtta taaaatagaa ttaaatggag tttcaaatca tacaaaagat aaaaagagta
    14101 gagtcatatt tttggatgat atacctgatg atacggatga tattaaattt accaaagata
    14161 taccaagttg gaaaagaatg tgttattgta ttttaaaaaa tgaccatatg tgtagattta
    14221 tgggatttgg tcctacaaaa gaacagagaa ttagaacgga atatattaag aagaaatatg
    14281 aaaaaattca ttagatagga gttaagatgc tatggaatat aaaagtcctg tatatggaat
    14341 catcgcagtg ccaatcgaaa agatagaatc taacgactat aatccaaatg cagtagcccc
    14401 accagaaatg cagttgttgt ataaaagtat aaaagaagat gggtatacaa tgccaattgt
    14461 ctgttattat aatgaggaaa aggataagta tattattgta gatggttttc atagatatag
    14521 agtaatgctt gaaaatgagg atatatatga tagagaaaat ggacttcttc ctgtttcagt
    14581 aattgataaa tctcttgatg aaagaatggc aagtactatt cgacacaatc gtgcaagagg
    14641 ttctcataat gtggatttaa tgagtaaaat tataactgaa ctttgtgaaa ttggaaaatc
    14701 tgatgaatgg atatcaaagc acctgggtat ggaagttgat gaaattctta gattgaagca
    14761 aataactgga ttagcttatt tatttaaaga taaagagttt ggtaatgcat ggattccctt
    14821 tggctctgat atagaagaag aaaattaaat agatttatta aaagaaaaag atttattaaa
    14881 aaagaaaatt taaaatatat attaaaaaat aaagagtttt aatattatat gtaagtacag
    14941 aaaaaagagt aggaaaatta tcctattctt tttttatttt tataattata ctcttagaaa
    15001 aaataaaatt atataactaa atgtatttta atacaagttt atttataaaa aaatagtatt
    15061 aaattgtata tttatatcgt ttttaataaa aaataatcac attttattta aaaatgaata
    15121 atatatagta aatagtaatt aagctataaa aaattgtata aactctatat tatttattta
    15181 aaatagatat ttatgaaaga ttaattagaa aaattttaga ggtaaaataa gaaaaaaaga
    15241 tacttattta atcatttaat cttattaaag acctattaaa actaccagtt ataatataga
    15301 accagtatac aatttttaaa aataatgcta ttttaaaatt ctaaaaatta aggaggataa
    15361 ttaatgggat atttaaaaga ggataaacaa gactattgtt gtgaatttgc tagaccatac
    15421 atcaatcgtc aaatttatga tgacacatac aatccaaaaa cagcattaaa aagaggtact
    15481 ttatttcctg aattagattt aatagagtca aataactata atgattggct atatgcaaat
    15541 cctaaaaata gagttagagc taaaaaaggg ggtaacatgt actaatgtca ttaaatagaa
    15601 gagaactttt agagagaatt tcagaatatc aatttgcctg tatagaatta aatttatatt
    15661 tagataacaa tccaagggat aagaaagctc ttgattcata caacagatac tgcgataaat
    15721 ttacacaagc tgtgtgtgat tatgaatcta aatatggagc attaactaat tttggatatg
    15781 aatcaagtga atatccttgg tcatggatat ctgaaccttg gccatgggac aaatcatttt
    15841 ataaataaaa ttattaaact ttaaaattag atttattatt aaatatatat taaggaggag
    15901 taagataata tgtggattta tcaaaaaaca ctggaacatc cagttaacat aagacaagca
    15961 gaccctagaa tggcaaaata tatcatgact cagttgggag gacctaatgg tgagttggca
    16021 gctgcaacta gatatcttca acaaagatat actatgccaa ctggaaaatc tcgtgcactt
    16081 ttaactgata taggtacaga ggaaatggct catgttgaga taatttcttc agtgttatat
    16141 caattaatag gcaattgtac tccagaagag cttaaggctg ctggacttgg tagtaattat
    16201 gctaattttg gacatggtct tcagccagta gattctaatg gagtaaactt tactacaagt
    16261 tatattaatg tctttggcga ttcggtaact gatttacatg aggatatggc tgctgaacaa
    16321 aaagcattgg ctacgtacta tcaattaata aatttaactg atgaccctga tttgaaagat
    16381 atattgagat ttttgggtga gagggaagta gttcactatc aaagatttgg tgaagcatta
    16441 atggatgttt atgagtttac agagtgcaag catcagtttt aatgaagaat tgaaagtgaa
    16501 tggagaataa gcatcatttt taatgaagaa ttaaaagtga atggagagta agcatcattt
    16561 ttaatgaaga attaaaagtg aatggagagt aagcataagt tctaatgaag aattaaaagt
    16621 gaaaagagaa taagcataag ttctaatgaa gtattaaaaa tgaaaagaga ataagcatca
    16681 tttttaatga agtatcaaaa ataaaaagag tgtaaatatt agctctgata aactatcaaa
    16741 ataagaggta aaagttttag ttgatttctt ttatctctta ttttttattg attaaacaga
    16801 ttactttgct atttaaatat attattttag caaaaaaagt ccaatcaaaa gttcaaagta
    16861 ttaccatagt tcaaagcatt gccgttgtta gtaagttttt tacaatattt tttatttact
    16921 ctttggataa tcaaaagaaa taaaaaatca tatctctttt tttatatttc tgtacacttt
    16981 tggagaatat cccgtttttt ctttaaaaca tttactaaaa tagattattt gatgaaaaac
    17041 aacttttata gtaatgtcac ttattagctc atttgtgcct tttagaaatt gagttgcttt
    17101 taataaacaa aactcagtaa aatatttata aggtatagta tttaaactta gttcaaatca
    17161 tctggagcac tctgatttat tgatattacc actgcttgat agtactccaa aattaagttt
    17221 tcacaatagt acccttcaat ataatgtaaa acaatagtat ttttcaatat aacgtaaaat
    17281 tttttgcata tggatattaa ttatattttt gtgttttatt ggtggcaaaa caatattttt
    17341 tatcataata agccaaagga aagaaacaga aactaatgct tcatacatat acagttcatt
    17401 tttacttttt tctaacctta ttaatcgttg tagaatagaa aacactttat tgcgtcaatt
    17461 atatttatgt gtaaaatgat aaatagcaaa ttgttcgttt tctgttattc tatctactaa
    17521 cgattttact ggatttctaa cataaaaata cttttctttt ttacagccta ttcttacttt
    17581 tcccatttga aagtattatg atattacttg atgctatatc gatatttttt tggtctattt
    17641 agtgataaaa ttataagata cacttctata aaagttaata cagtaggaag cttaaatgta
    17701 tgaattttat atccatcaaa gggaaaggga aaaaaggatg aacagatgca ggtaaatata
    17761 aaactaatat gatatgagga tagatattat aacgaaagtg tagttagaag gaaattatat
    17821 tagtatgttt ttacataatg gtagatagaa aagaagtgtc taatgatttg agtgaagttt
    17881 tcagaatata aggaggaatt gtatgcaata tattagctat taccatagtc caattggaaa
    17941 tattctttta gcatcagata atattgggtt aactggtctt tggtttgaga atcaaaagta
    18001 ttatgcttat aatcttgacc aagaacatca agaaaaagaa ttgccaattt tcgagcagac
    18061 aaagaaatgg ttagatattt atttttcagg aaaagaaccc gattttacac catcactcca
    18121 tatggtaggt actccttttc agactacagt gtggaaaatt ttacaacaaa taccatatgg
    18181 taaaacaatc acttatggag aaattgcata taaagttgct caacaaaaag gaatatctaa
    18241 aatgtcagca caagcaattg gtggtgcagt agggcataat ggaatctcta ttattattcc
    18301 atgtcatcgt gttgtaggaa caaatgggag tttgactggg tatgctggtg gaattaatag
    18361 aaaaataaaa ttgttatctt tagaaaaagt atctgtgcaa cattatttta tcccaaagaa
    18421 agggagtgca ttataaagcc attaaattta gaaattctta atcatttatt tgatatacaa
    18481 acatctaatt ttgaaagcaa taacttgcaa ttttaaaaaa tgattattta aactatatgt
    18541 tatacaacct tattcctagt aaacattata caactttaga ggtagttttt agagcttgta
    18601 ttttggaagt ttattttctt ttttcatgtg agtagttata tgtttagagg aagtaattta
    18661 tatgctacaa acaggaaaac aaggagcaga caaaaaatac ttagataata tgttttttgt
    18721 gaaaggttat gttgaagaac ttctattttt agacaacaat tataatattg tattttcatg
    18781 tattgtattt catcattgta caaatgttca aaatatattt tgtatatttt ggaaatggta
    18841 agagtgttaa atgtaaggga aaaatttata atgattgata cttaagctac tcattaagta
    18901 ttaagaacca tacaagataa ggttgaaatt tatatgtttc gttttatgta aaaaatgtaa
    18961 gtgagttaga aatgaaagaa ttatttataa aaaatagatt aagtattgga aaatatgaaa
    19021 aatagatgtt gaacaaaact tagtcgatta gttaaattta accaaacact taaagtatca
    19081 aaagaaaaaa ttattactct taagcaagaa gatataaatg gaaaaatgaa aacaagattt
    19141 tatcctttta taagtgataa ggggatgtgt tttaatcaaa gatggacttt tattttaggc
    19201 tgaaaaatta tataactata ttataggata taagggagat acacaacttt ttagtgtcca
    19261 atctccctta ttttttatta ttatatcaag actcatttag tcgtgttaat tttaggataa
    19321 aatgagtatt tttttaataa attatttata agtaaagtgt gttgtcggat aatcagtatt
    19381 tctgtataaa atttggtata actttaaaga agtatgtgaa attttcaggt attttttact
    19441 atggtatatt atttaactga ttttaattta gcaatatcat tcgaattctt agatgtgact
    19501 atctctatat tatttaaatc atttttaata tctgatgtat cttttactaa tgaagaggta
    19561 tgtttaatca ctgtatctaa tgtatttctg ttaattttta catctgactt aatttctgta
    19621 acatcactct gaatagtatc aagtctacta ctagtttcaa cttgtccagt ttttaagtct
    19681 ttaatatcag gttccatatt gtctaactta ctattgactt ctttaatttc aacttgcata
    19741 tcagtaatac tgtcttgcat actattaata gtgccatcca tactactgat actgccttgc
    19801 atatcgctaa tagtgccatt cataccactg atactacctt gcatatcgcc aatagtgcct
    19861 tgcataccac taatagtgtt ttcgatacca ttgatattgc cttgcatact actaatagtg
    19921 ccttcgatac cattgatatt gctttgcata tcgctaatag tgccttcgat accattgata
    19981 ttgctttgca tatcgctaat agtgccttcg ataccactga tactaccttg catttcctgt
    20041 aataactcta atattttttc atccatcact atcacactcc tgttttatta ttataacata
    20101 atttaggtgt tatattccac aaacgctatg tcatatttaa tttttaatca tatgattatc
    20161 tgctattcaa aacatggtta aatatatcta tattgagaac ttttttatta atgaatctta
    20221 tgtattgtct aagtttctaa gatactgtaa taagtgtttt tgaggcatgt gtggttatat
    20281 ttgtatttaa aactgctggt aatatcatat acttttaaat ataccttaag ttatttatat
    20341 tgattacttg tatttgaata atttgattag tagcttcctt tttatctctt tttattctta
    20401 gttttaaact ttcatatttc cttgaaaatt tattggcaat gaaagtgcat gaatttttta
    20461 gctatttttt atgttacaat atgaatatat aacaattcga caaattggat ttttgaaagg
    20521 agtaaaatgt tatgaaaatg ccaaaagaga gtattgatac gattatgttt gctccttgtg
    20581 gaatgaattg tatggtttgc tataagcatt gttatcacaa aaagccatgt gctggttgtt
    20641 tgaatggcga tacaggaaag ccagaacact gccgtaagtg taaaataaag gattgtgtct
    20701 gtcaaaaagg gttgttttat tgttttgaat gtttcaattt tccttgtaaa ctcataaaaa
    20761 atcttgaaaa aagttataac aagagatatc aagcaagcct tatggaaaat agtaaatttg
    20821 ttcagcagta cggtttagag aagtttatgc aaaagcagaa ggagagatat acttgttcta
    20881 aatgtggagg aattatatct attcatgata gggaatgtag cgagtgtcaa gaaaaagtga
    20941 aatagctaaa tcactgttta tcaagagaga aaaaattgta atatatataa aggtggatta
    21001 tattgaggtg gtatatagtg ataggtttaa aatgtggtat ggttaaatta ttggaacatc
    21061 agatgatatg ggataaaagt gcaaaagatg tcattatatt attgaaaagt atatgggata
    21121 agactgccat tgatattcaa cacattggaa gcacttctat tcccagtatt agcgcaaagc
    21181 ctattattga tattgttgta ggtgttgctt ctttagagga agctaaatta tacctcgaaa
    21241 ggttagagca atgtggaatc gtttttcgag gtcaggatgt accaaaacaa ttactttttg
    21301 ctatgggaga ttttgagaaa aatactcgta ctcaccatat tcatgttgtt gaatggaatg
    21361 gtgttgcatg gaataattat atcaattttc gagattatct aaatactttt acagacaaag
    21421 caaaactcta tgatagtcat aaacaaaaat tggcattaca gtttgaggac aatcgtaaaa
    21481 tctatacaca gagaaagcaa gaactaataa atattttgct ggaagaagca cgactgtgga
    21541 gaataaatac ctaaaagaat aaatttacat ttattgagaa attgagcaat tattttctta
    21601 tatttagtaa ataaaaatct atttttgttg attaaaaaat atctgtacac actcatgact
    21661 ttagtcattg gagattcaga ttgtgtagaa ttattggatg aaggaggaac agtatgaaaa
    21721 aggatacatc tcatattatc aaacgggcag agcactttca ggtaattttg attggtgaag
    21781 gacttatggt tggggctgtg gctggtttga ttgtgctttt atacaggata cttttagggc
    21841 aggctggtac ttggcttagc caaattttaa aatttgtaga aggttctaca ataaaaataa
    21901 tagcttggtt tgcagtactt gcagtacttg catggattgt atcaaagttg gtggactggg
    21961 agccaatgat ttctggaagt ggtatccctc agcttgaggg ggaaatgaca gggaaaataa
    22021 aacaagtatg gtggcgagtg ttgccaacaa aatttattgg aggattctta tcactcatgg
    22081 gtggtcttgc tttgggaagg gaaggtcctt ccattcagct tggtgctatg gcaggtaaag
    22141 gtatttctag agctcttgac cgagggaaga cagaggaaaa attcctgtta acctgtgggg
    22201 caagtgctgg attatcagca gcctttcatg caccactggc gggtgttatg ttttcacttg
    22261 aagaagtcca taaaaacttt tcagtatctg ttttaatttc tgtgatgaca gcatctttga
    22321 cagcagacta tatttcagcc aatttcctag gaatggagtc tgtattccag tttgattaaa
    22381 aaatagctac gcacacttgt gactttagtc atgagttagt agctaaaata gtcagcatat
    22441 agggaaacct atatgtagag ataggataga acctatccaa tactacttga attgctggaa
    22501 acccctaaag ctaaccaaac taaaacataa ggatgaaata aacctaagtg tgaaagttac
    22561 gaaagtagaa aaaattggtt agatggtata aggttaaatc ctaagtactt taaaatgggc
    22621 aatcagcagg taaactccga ataggagaaa cttcaacgac tattcctctt gagggaagta
    22681 cactacaagc tattggtagt ggaagtgggt agaccttaac ggataatgcc gaaggataag
    22741 atatagtctg tgcttgcatg aaagtgtaag aagttcataa gagaactgca taggtagtag
    22801 cgaacttatg tgaacgacaa cctcaaaaat gataaaagtt aagacttacg gttcttaaat
    22861 atgttattta aaattaaata taaaaccttc taaataattg ttttaaataa ttacatttgt
    22921 taacattatt ataagagaat ggatttgtcc tagttgtaat gaaactcacg atagagatat
    22981 aaatgcaagt ataaatatat taaaagaagg attaagacta ataacaattc aaaataaata
    23041 acttatgtaa gaaccgtagg aactacgggg atagcctgtg gagaattagt aagacatatg
    23101 ttagtatgca aaattctatg aagcaggaac cctgtgactt tagtcatggg aggttcagat
    23161 tggaaatgtg ttgccacaag attattatgg attaatagtg attttaggtg ttattcttgg
    23221 agttatgggg gcattttaca actggtttac tctatatgtg cagtctttat acaagaagat
    23281 tcctaaaatt ggtacgtttg gaaaactgtt gattccattt ataatggctg gtattcttgg
    23341 gcttgttatg cctgatgttc tggggagtgg acacaattta gttgaagaac ttacaagtca
    23401 tgaatatatt tttggaatgg ttgttttgat ttttgttata cgttttatat tttcggctgt
    23461 tagttttggg tcaggtgcac cagggggaat attttttcca ttgcttgttt taggagcatt
    23521 tataggtgga atatttggta tggtaggtgt taaagttttt ggaatgaatc ccgattatgt
    23581 aaataacttt gtgcttttgg ctatggcagg atattttaca gctattgtgc gtgccccttt
    23641 gactggtatc atattaattt ttgaaatgac aggttctgtt agtcaaatgc tttcactatc
    23701 agtaatttca attgtggcat atattgtggc tacacttatg aagtctaaac ctatttatga
    23761 aagtcttctt gagaggttac ttgaaaaaaa tggagaacct gtacataaag agaggggcga
    23821 aaagatatta gaccagttct ctgttatgtt tggctctcct gttgcgaaca aggcaattca
    23881 ggatgtacag tggcctgaaa attgtctttt ggtagcaatt caaagaggtg gagaagaaat
    23941 tattcctaga ggtaagacaa ttcttagacc aagtgatgta attgtgacta tgacagatga
    24001 gagagatagt ggtgctgtgt atgataagat ggaaaatttg tgtaaagaac atacgtcaca
    24061 tattttttag ggataatgat gaatgtttaa taatgataga atatttaatg aagatttgat
    24121 taaaaaattg gtaatttgaa agagagttaa ggaattaata taagaaaatg aaaatgtgat
    24181 atcttagatg taaaagagtt tgaagaaaat aattgtatat atttgttaat gagattatat
    24241 ggactaatgg tatatttata ctgtgctaaa agttgcacta ttgtatgagg aatgggaata
    24301 aagggtttga aaaaataggt agaagatttt tcagatattc ttactgggat attttaatta
    24361 atatatttta attgcgatat tttgggaaga atagaattta tttataaatg aaaataatta
    24421 aaaggggtta aggttgtatt agcccctttt gcttatagag tttggaaatg gtatcttgat
    24481 agcagttgtt tcatgcttat tatattttat tacatatttt aaaattgacc ttattactcc
    24541 taaatcattg ttatatcaac ttttaaaaca ctttcaagac aatcgcctat tgaaaacaaa
    24601 gttaattaaa aacctacata tcagtttagt attcgtgtag atgattatat aaatataaaa
    24661 gtataagaaa ggtgagtatc tgtggttagt tcatttttaa atgatatctt tagaacaatt
    24721 ttagtaagtt gtatttttat agttatttta ttagtcttta gaataacttt atttaagatt
    24781 ttcagtaaaa aatttaatta ctatatatgg cttattgtga ttattaagct atcattacca
    24841 tttatgaatt atacttttat atttaatgag tcaaaatata atggtaatat taataagata
    24901 agtttaggca attttaatag tatttctatt gtatatagta ctgttttagt ctctgtttgg
    24961 attgctatta cgatatttta tttagtttat actttattga aatatattaa gcttaaaaat
    25021 atgataaatg atttgtctta tgatgttgag gatgataaga taaaaaatct ttatgaaaat
    25081 ttattaaaag agcttaagat aaataaaaaa atacggctta aatattcata tgaagttgaa
    25141 agtccagtat tttttaattc gtgtgtcatt ttaccaccaa gtgattatac attaaaagag
    25201 ttaaactgga tatttaggca tgagttgatg cattttaaga gtaaagacct ttatattaag
    25261 tatttggtga tatttttaaa atgtgtttat tggtttaatc cttttgtgta tataatggag
    25321 aagtttatag atttggattg tgaattttat tgtgatgaaa gagttttgaa gaattgtacg
    25381 atagaagaga agcaggatta tgcattgaca ataattagtg caatgagaaa aggttcaaat
    25441 agttcaaata aatttgtggc tggattacat aaggagtcag atattaaaaa aagagtgttt
    25501 agtatgttta atgaaaagta cagaaatggt attttgatag cagttatttt atgtttatta
    25561 tcttctatta catattttaa aattgattta attactacta aatcaatatt ttatccactt
    25621 tcaaaacaaa cacctattga aaacagaact aattcaaaac ctacatatca gattaatgtt
    25681 tatatagata attaaaaaat acaaagttta acaagagatt aatataaata attttaataa
    25741 gtatctttca catatgttaa atttacttta attatattaa agccaatgaa ttattcttta
    25801 gaagctccaa tgccagtaaa tacaggtaaa gaaaaatatt ttactacaat tgcagattaa
    25861 aaagtgttct aatatttaaa gaaatacaca agtgtaagaa gggtaaaaat ctgttataat
    25921 acattaaaaa ctaaatttag aaaaatttac ataattagaa aaatgatttg ataaaaaata
    25981 aagttaaata ttaactaagt aaatttgaaa aagaaaaaat ataaagtaca aatttaaaag
    26041 gaggtaacta atgaaaaaga agttggaaga tatgacttta gaggagttat ggaacttgtt
    26101 tcctatattt ttgactactc acaaagaatg ttggaaaaat tggtttaaag aagaacaata
    26161 tagactaact ggaatattgc caatgcaaaa aattgttaga ataagtcata ttggaagtac
    26221 ttctgtgagt acgatttatg ccaagcccat tgttgacata ctgattgaga taattcctga
    26281 ttataatatg aaagatatta aagatttgat tgagtcgaat ggatatattt gtatgtctga
    26341 gagcagtagt aggctttcac ttaataaagg gtatacagta gatgggtttg aagaacgagt
    26401 ttttcatttg catataaggt atgtaggtga taatgatgag ttgtttttta gagattactt
    26461 aattgaccac ccagatgttg caaaggagta tgaaaaactt aagttggacc tttggaagaa
    26521 gtatgagcat aatcgtgatg cttatacaga tagtaaacta gattttgtta gggagtttac
    26581 tgaaaaggca aaggtgttgt attttaatag atataattag aaataggtac aattagatat
    26641 ttatcttata tatcgtatta tattttttaa gaaagtaatt aatagaaaaa ggggttgttt
    26701 caaaatggag agataaatcc ctttttcatt gttgaaagga taaaaatata tttgatttca
    26761 tgtaaaaaag agtgcctcat caactaaaaa gtttattttg agacacacac atttttacta
    26821 aggtaaataa aatatcacat ttgattaaat tttaagttaa tgaatatatg tgtaaatatt
    26881 taattataag ttattataat tttacatagt atcaaacaat ctaatttgta ttatataaga
    26941 taatctaatt ttagactaaa ataatctaat ataaagaaat aaagaaaatt cattctcagt
    27001 ataagagata tccaattttc cattgtactt attaacaatt tctctaatat tctcaatacc
    27061 atatccgtga gaattactat cttttttatc tgaaataaat agttcttgtt ttctattgat
    27121 aggatttacc ttgttgtttg tcaataaata gctaaaatac tccttctcac aacgtgcctt
    27181 taataccact tttctatttg acaaatcagg aatcttcaaa gatgcttcta tagcgttatc
    27241 taaagaattt gaaaaaatag tacataaatc tataggttct atacccaagt gattgtctat
    27301 atctatatta aagtgcacat caacaccatt ttcttccaaa cttgtatgac gaagatttaa
    27361 aattgagtta agagcttggt ttttgcaaaa ctgtttgcca ctaagagtac ctatacctat
    27421 ttttaactga ttaaaatact ttttagctcc agcaatatct tcaatttcta aatacgattc
    27481 aatcatttga aagtgattat tcatatcatg tcgcattttg cgtatttgaa tttgttgatt
    27541 ttctagtaag ttatagtatt tttcttttag atgatttgct tgtttttcta tcttcatctt
    27601 tacattttca atcaatggct gtaaaagaag tatcacaccg atatttgcca gaattgctga
    27661 caagatgatt agataagtgc cataaggtaa gttgcctaag ataatattct tattactacc
    27721 catagggatt aaattagtag gtggcagaat aatagcaatt aatattgata aaaatgaaga
    27781 tatacatacc atatcaataa aaatccatat tttatttgat aagtattgtt ttatattgac
    27841 caatctattc tttaggaaaa tatgtattaa aaaccaaaat aataatttaa ttagagcaga
    27901 aattatctgg actattgaaa gtattaaaat atactctttt gagtgtataa gttcctcata
    27961 tatagggttg tttataaaaa gaaaattaag cccaattata ataggataaa atatcatgac
    28021 aactgatatt ataggaatta atttgctttt gctacatatt ataagtagta taaaatatcc
    28081 gaatagtgta aacaaaatat ttacggggtc ggaaagccat attatcattt gactaataat
    28141 agagtagccc aaaatcaata tgattttgaa aatccaatga ttcctaaagt ctataaaata
    28201 ggaagtcaac gtataaagaa aaaaggctat gaaaatattg attaatatta gaataaaatt
    28261 tatgcttgta gagattaaag aataagtgcc catttaatat acctttctat taattaagat
    28321 tctggaaact aagttttaaa aaattaaatc ttaaaaatta aaattctgga aattaaattt
    28381 caaagaattg attttgaaaa ataaaattct agagattgaa cttcaaaaaa ttgagtttta
    28441 aaagattgaa attttaaaaa ttaagtttca aaaaattaaa tttgaaaaaa aactctaaaa
    28501 actaagcttc aaaaaa
//
LOCUS       DAEPHU010000055        28417 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 01A10CD0081
            SAMN05941466-rid12468953.denovo.055, whole genome shotgun sequence.
ACCESSION   DAEPHU010000055 DAEPHU010000000
VERSION     DAEPHU010000055.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941466
            Sequence Read Archive: SRR6291087
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 28417)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 28417)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068158.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 22:43:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,892
            CDSs (total)                      :: 3,805
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 87
            rRNAs                             :: 8, 1, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 55
            CDSs (without protein)            :: 55
            Pseudo Genes (ambiguous residues) :: 0 of 55
            Pseudo Genes (frameshifted)       :: 21 of 55
            Pseudo Genes (incomplete)         :: 28 of 55
            Pseudo Genes (internal stop)      :: 16 of 55
            Pseudo Genes (multiple problems)  :: 8 of 55
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..28417
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941466-rid12468953.denovo.055"
                     /strain="01A10CD0081"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            complement(192..947)
                     /locus_tag="KR231_002485"
     CDS             complement(192..947)
                     /locus_tag="KR231_002485"
                     /EC_number="1.17.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate reductase"
                     /protein_id="HBH0004849.1"
                     /translation="MLKVIISGYNGTMGRVLAECVKKDNELELVCGVARSADEKGHHS
                     DTKLYKTMTDVTEKTDVIIDFSHHDTLEPILSYALKNNTPVVLATTGYDENDLNKIEE
                     ASKNIPILLSSNTSLGVNILIKLVKDASKMLEGFDIEIIEKHHNRKEDAPSGTATMIA
                     NAIREVLPESENTHGRYGRDCKRKPNEIGIHSIRGGNIISDHDVVFAGDNEVLTLSHH
                     SQSDEVFANGSIVAAKFLIGKQSGLYKMSDILG"
     gene            1387..2376
                     /locus_tag="KR231_002486"
     CDS             1387..2376
                     /locus_tag="KR231_002486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH domain-containing protein"
                     /protein_id="HBH0004850.1"
                     /translation="MLKEEKTYQEKDAKVFNGVAALIMILLFLVVSIGIMVFGIVKLD
                     SGFTGIGSLMLILGLVFIVVDFILFFGLKMINPKEAIVLVLFGNYYGTIKKEGYYWVN
                     PFCSAINPAVSRINVSKSSSDEKVDISTNSRGKKVSLKTMTLNNEKQKVNDLLGNPII
                     IGVVVIWKVIDATKAVFNVDNYNTFLSIQCDSTIRNVSRLYPYDVSEDGDEKSLRGSS
                     QEIADRLKDELQSRVDIAGIEVCEVRITHLSYAPEIAAAMLQRQQAEAIIAARKKIVE
                     GAVSMVEMALTNLSENNVVTLDEERKAAMVSNLLVVLCGNKDAQPVVNSSSIY"
     gene            complement(2828..3544)
                     /gene="dapD"
                     /locus_tag="KR231_002487"
     CDS             complement(2828..3544)
                     /gene="dapD"
                     /locus_tag="KR231_002487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3,4,5-tetrahydropyridine-2,6-dicarboxylate
                     N-acetyltransferase"
                     /protein_id="HBH0004851.1"
                     /translation="MVNLNDAYEIARYIKEVKKKTPVKVYVNTNSLHFQSTDKFKVFG
                     SNGSYIFVGDYEDIMEVLDKHGNDITDTHVEYDRRNSAIPLKNTLSEHARIEPGAIIR
                     DMVTIEKNAVVMMGAVINIGAVIGEGSMVDMNAVIGARGTLGKNVHLGAGAVVAGVLE
                     PPSATPVIVEDDVLIGANAVILEGVRIGKGAVVAAGAVVTTDVEAGAVVAGSPAKVIK
                     MKDEKTADKTKLMEDLRNLD"
     gene            complement(3768..4517)
                     /locus_tag="KR231_002488"
     CDS             complement(3768..4517)
                     /locus_tag="KR231_002488"
                     /EC_number="1.17.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate reductase"
                     /protein_id="HBH0004852.1"
                     /translation="MLKVIATGYDGKMGKILADTIREDNELELVCVAARGLDSYEGDL
                     KIYEDMSTIVEEADVVIDFSHHSNLDNILSYVLKTKTPLVIATTGYNDDEMNKIREAA
                     KVIPVFQSYNMSLGVNVLVKLVKDAAKLLEGFDIEIIEKHHNRKVDAPSGTAVMIANA
                     IKEVLPNVENNYGRYGRSAKRQPNEVGIHAIRGGNIVGEHDALFAGDNEVLTISHQAQ
                     SRGIFASGSIAAAKYLVKQKPGFYNMDSMLG"
     gene            complement(4584..5471)
                     /locus_tag="KR231_002489"
     CDS             complement(4584..5471)
                     /locus_tag="KR231_002489"
                     /EC_number="4.3.3.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate synthase"
                     /protein_id="HBH0004853.1"
                     /translation="MIFKGSAVALVTPFTKDNKVDFDKLGELVEYQIANGTDAIVSCG
                     TTGEANTMTDEEQLATIKYVVEKVNKRVPVIAGSGSNDTMHSVNLSQEAEKLGVDALL
                     IITPYYNKANKAGLKRHFETIANSVKLPIILYNVPGRTCVNISPSLIVELAKIDNIVA
                     VKEASGDLGQVAEIASLVPDDFAIYSGNDDTILPLLSLGGQGVISVLANVCPQETHDL
                     VAKFFEGDIEGSRKLQLGMDALIAALFIEVNPIPVKTAMNLLGFNVGDLRLPLAEMDP
                     ANLEVLKKELVNFGLKVNA"
     gene            complement(5588..6589)
                     /locus_tag="KR231_002490"
     CDS             complement(5588..6589)
                     /locus_tag="KR231_002490"
                     /EC_number="1.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate-semialdehyde dehydrogenase"
                     /protein_id="HBH0004854.1"
                     /translation="MKKVNVAIIGATGMVGRTFLKVLEERNFPIENLFLFSSSKSAGS
                     KVMFCGKEYIVEELKETSFTDRGIQIALFSAGGSISEKYAPIAASNGILVVDNSSQWR
                     MNPDVPLVVPEVNPEAIKNHKGIIANPNCSTIQAMVPLKALDDKYKIKRVVYSTYQAV
                     SGSGVKGVEDLEKGMNGNPTGFYPHQISYNCLPHIDSFTENGYTKEEMKMVNETMKIL
                     DNYDLKITATTVRVPVKNGHSESINVEFNNPFELDDLVKTLEEAPGVVVVDNPAKNEY
                     PTAVEFDDRDEVFVGRIRRDFSVDNGVNLWVVADNIRKGAATNAIQIAEMALSYDLV"
     gene            complement(7014..7895)
                     /locus_tag="KR231_002491"
     CDS             complement(7014..7895)
                     /locus_tag="KR231_002491"
                     /EC_number="4.3.3.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate synthase"
                     /protein_id="HBH0004855.1"
                     /translation="MLFKGSAVALVTPFTEDNNVNFEKLGELIEYHIENGTDALVVCG
                     TTGEATTMSESEIFAVIKYTVEKVNKRIPVIAGTGSNNTMLSVHMSQEAEKLGVDGLL
                     IITPYYNKTNEKGLKLHFETIANSVKLPIILYNVPGRTKVNIKPSVVAELAKIDNIVA
                     VKEASGDLAQVAEIAKLVPKDFAIYSGNDDTILPLLSLGGSGIISVLANICPKETHDL
                     VTKFFEGDIEGSKKLQLDMDALIAALFIEVNPVPVKTAMNILGFNVGDLRLPLAEMEE
                     TNLNVLKQELTNFGFKF"
     gene            8218..9411
                     /locus_tag="KR231_002492"
     CDS             8218..9411
                     /locus_tag="KR231_002492"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase"
                     /protein_id="HBH0004856.1"
                     /translation="MDTLKELFKIGSGPSSSHTMGPQRAAERFKNENPDAESFRAILY
                     GSLAATGKGHLTDYIIEKTIAPKKVEIVWEEDIIKDFHPNGMKFEALDKDKNVTAEWT
                     VYSVGGGTIAEEGQRNSKSNSIYHLDTMDEIVKWCKENNKTLVDFVLECEPKDIKDYI
                     KTIKDAMRKSIDDGLSTDEIIPGKLLLKRRASTFYNAYKKDKSFSTLVYAYALAASEQ
                     NASGNIIVTAPTCGSAGVIPGIFFAMQDFYNYDDEKIIEALLVAGIIGNIIKTNASIS
                     GAEVGCQGEVGAACSMAAAAVAYLKGGTIDHIEYAAEIALEHHLGMTCDPVYGYVQIP
                     CIERNAMAAQRAYDAANYALLTDGSHSVSLDQVVETMKETGIDMMDKYKETAKGGLAK
                     HFFSC"
     gene            9617..10735
                     /locus_tag="KR231_002493"
     CDS             9617..10735
                     /locus_tag="KR231_002493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyldiaminopimelate deacetylase"
                     /protein_id="HBH0004857.1"
                     /translation="MREASYLQEQLYKHRKSLNPIAEIGRKEYKTSKYIRDYLDKLGI
                     EYEVYLETGIVGVIEGKRPKKDIAFRADIDGLHSEEGVKHLCGHDGHATILLGLIEYL
                     NDNKEDLNDNIVFIFQPAEEGPGGAKALIDEGVLRKYNIDEIYGLHIYPELPEGYVGT
                     REGYFMAQIGDIDIEIVSKSGHGAMPQNGIDGIVIASNFVSSLQTIVSRNISPIDNAV
                     LTIGRIEGGARRNIIAENIKMEGTMRCFSPEVYEKMKLRVRELARGFELAYNCKVNIN
                     IIDDYIAVKNDKDLYQEFVEAIGSDTVVELEPLMISEDFSYYQKEVPGLFFMLGSRNE
                     EKGFVNGLHNINFNFDEKICVNALNVYSKLLKYKEAID"
     gene            10866..11111
                     /locus_tag="KR231_002494"
     CDS             10866..11111
                     /locus_tag="KR231_002494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906336.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="small, acid-soluble spore protein, alpha/beta
                     type"
                     /protein_id="HBH0004858.1"
                     /translation="MKEKVQREKKITNGKNTKILTNDDIMKYEIASELGLMDKVGERG
                     WAGLTAKEAGRIGGMLTSRKKRLKKIVEEQNKKDESI"
     gene            11098..11844
                     /locus_tag="KR231_002495"
     CDS             11098..11844
                     /locus_tag="KR231_002495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HBH0004859.1"
                     /translation="MSQYSDFAFVYDELMNEVDYNGWVKYIEDIIDSEGVKVKNILEL
                     ACGTGNLTIPLTKKNYDIAGIDISDEMLSVAREKSEKEGVELVLLQQDISELDFEISD
                     LDCVLCACDGFNYITYDDDLENVFSKTYELLKKDGIFIFDISSFYKLANILGNNMYGE
                     NREDIAYMWQNYFDEEENLIEMELTFFIKDECGKFERFEEIHQQRAYTEDEIVDMLEK
                     SGFKDIKYYGDFTFDKPSEESQRIFFVCKK"
     gene            12129..13004
                     /gene="hslO"
                     /locus_tag="KR231_002496"
     CDS             12129..13004
                     /gene="hslO"
                     /locus_tag="KR231_002496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Hsp33 family molecular chaperone HslO"
                     /protein_id="HBH0004860.1"
                     /translation="MRDYVLRATSGNGQVRAFVATTRNTVEEARRLHETTKVATAALG
                     RTLTATSIMGLMMKNDSDKLTVIIKGGGPIGTIIATSDSKGMVKGYVGNPQVEVEDYP
                     NGKLNVAAAVGTEGVVKVIKDLGLREPYNGTYPLVSGEIAEDFTYYFAVSEQTPSVVA
                     LGVLTKEDEVEFAGGFIVQLMPDAEEETIAKLEENVAKLPSITNMLKEGKSPEDILNI
                     VLDGLEPKILDTCEVGFMCECSKERVKTALVAIGKKSLAQIIEEDKKAEVGCQFCNKK
                     YMYSEEELLEILKEM"
     gene            13395..14195
                     /locus_tag="KR231_002497"
     CDS             13395..14195
                     /locus_tag="KR231_002497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PIG-L family deacetylase"
                     /protein_id="HBH0004861.1"
                     /translation="MESKTKYIGISILILLMIFLIAKNFNGKLEIPIPESNSRKFKSA
                     AVFYPQHQDDEVLWGGSAIVDAIKQCGVDNVYVVLVSDGSGVNVFKANTKFRNLTRKQ
                     KEELRNNEFKSALRELGVKPQNVIILADIDKKEGTHYELMEKTILDFEHKFKGNVTHI
                     AHHYKYDDHIMHRKNGEVLKKLKREGKIKDDLYFVKPKYVKYIPRNERAIYKAMDFDD
                     YNKVKSACYEYKVVNSKRKMYGIGYISAHSYFEHLLNDPELTSVLSED"
     gene            14722..16962
                     /locus_tag="KR231_002498"
     CDS             14722..16962
                     /locus_tag="KR231_002498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrA"
                     /protein_id="HBH0004862.1"
                     /translation="MNNEFIILKGCKENNLNNISLKIPKRKITIFTGVSGSGKSSIVF
                     ETIAKESQRQLNERFSTFVRSFLPKYGEVKADCIENLSTPIIIDQSRLGGNSRSTLGT
                     ITDVNSFLRALYSRFGSEYIGNANMFSFNNIDGMCPHCHGLGKKLVPNMNQILDMNKS
                     LNEGAILLSGFGVGSWHWNIFAESGFFDINKRICDYSEVELEKFLHGKAEKIKIENAG
                     QTNMTYEGLMVKFNRLYLSREGEISEATKKKLSKLLIEDRCPICDGRRLNERVYRSLI
                     NGYNIADLTSMQIDELAEVIKSIDEPEAQPLIKGIIEKLNSIIDIGLGYLTLDRETSS
                     LSGGESQRIKMVKYLNSNLVDLMYIFDEPSVGLHPKDVYKLNNLLKKLRDKGNTIIVV
                     EHDPDVIKIADHIVDVGPKAGKYGGEVVYEGSYENLLTSGTLTGNALSKFLPIKESVR
                     EHSGYLEVKNCNKNNLKNVSIKIPKGVLTLVTGVAGAGKSTLIKDEFLKQNPSAVLID
                     QSPVSANSRSSLATYSGIMNNIRSIFSKTNGVNASLFSSNSEGACDNCKGSGIVEMNL
                     AFMESIKSTCNVCEGKKFKKEVLEYRFQGKNIIEVLEMSVLEAIEFFNLKQIKTKLQC
                     IEKMGIGYLTLGQTLDTLSGGECQRLKLASELNKESSVYILDEPTTGLHMADIENFIS
                     IIEEIVDNGNTVIIIEHNIDVIKRADWIIELGPEGGTKGGRVIFEGIPKQLCNNKISL
                     TAKYIV"
     gene            17376..18911
                     /locus_tag="KR231_002499"
     CDS             17376..18911
                     /locus_tag="KR231_002499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HBH0004863.1"
                     /translation="MINDILTLLSERSDFFIKLSIEHLMISIISIIIAIVLGGIIGII
                     VSEFHNSSKPILGTINFLYTIPSISMLGFLIPFSGIGNTTAVIALTIYALLPMVRNTY
                     TGITNVDKNILEAARGMGSTDFQILYKIKLPLALPVIMSGIRNMVIMTIALAGIASFI
                     GAGGLGVAIYRGITTNNTIMTITGSILIALLALIFDFILGLVEKFFQRKRKKKNRKKV
                     FAILGSLILIATIFTSYLFNPSKTQTIHIATKPMTEQYILGEMLDILIEKNTGLNVEI
                     TQGVGGGTSNIQPAMENGEFDIYPEYTGTGWNMVLKKNELYTESMFSKLQSEYKTKLK
                     MQWTGMYGFSNSYALAVRKEVADKYNLKNITDLKDVSSKLTFGAEYDFYEREDGYTPL
                     CNTYGLNFKDTVDLDIGLKYQAINEGKIDVMPIFTTDGQYSVSDVVVLKDDKNFYPSY
                     QCGNVVRLEVLEENPELSKVFKMVGDILTDKEMAKMNYDVENNNLEPREVAREFLNKK
                     GLL"
     gene            18927..19688
                     /locus_tag="KR231_002500"
     CDS             18927..19688
                     /locus_tag="KR231_002500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH0004864.1"
                     /translation="MTPIIQFKNIKKQYNDKTIIDNLNLDIEKGEFLTVIGSSGSGKT
                     TLLKMINGLILPDGGNILINQTDIKNEDLIKLRRRIGYCVQGSVLFPHMTVEENISYV
                     PNLLSKKNKLEVKSAVNKWMEIVGLPNDMKVRYPSELSGGQQQRVGIARALASSPEIL
                     LMDEPFGAVDEITRKQLQKEIKEIHKKTGVTIIFITHDIYEALILGTKTLVLNHGVVQ
                     QYDTPENILNTPANQFVDQLLNIRKSIIDDDNLKE"
     gene            20026..20895
                     /locus_tag="KR231_002501"
     CDS             20026..20895
                     /locus_tag="KR231_002501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HBH0004865.1"
                     /translation="MDNNLITIEKTLDYIEKHLLDEMLDLNVISKEIGYSKYHLHRMF
                     TSVVGFSVHNYIQRRRLTEAARMLIFTEKPIIEIALISGYDTQRSFSRGFKKMFKRSP
                     NFFRRHQDFLPLQLKFDIHNRKKLRGDMVLDVKKVNCADINIVGYSGKVRKGFHIIGK
                     CWRDLHKNKEMIENKVDLGFLIGVSDYSNFKEIENTPTFTYIAGAQVATFGKLPNGME
                     KFVLPKSNYIVFTFIGKNEDSMQNVVEYIYQEWFPNSSCQFNENNLYDFVKYGEKTDE
                     NGLSEIQFWVPII"
     gene            21224..21475
                     /locus_tag="KR231_002502"
     CDS             21224..21475
                     /locus_tag="KR231_002502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3781 domain-containing protein"
                     /protein_id="HBH0004866.1"
                     /translation="MNVENELLKNLDRLHTTELGVVRIKKNLSLETNDVVNWCKTKIE
                     SPNAIINRKGKNWYISVYDCIITVNAHSYTIITAHKEKK"
     gene            21587..22366
                     /locus_tag="KR231_002503"
     CDS             21587..22366
                     /locus_tag="KR231_002503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HBH0004867.1"
                     /translation="MNDTVKEKLAESLTSDTTDILPYLPYLLQDFWELGSSPEQMLQL
                     FRKHIPFNEDTKVLDLACGKGAVSVKLAKELNIHIKGIDLIPEFIDYARRKAIEYKVD
                     ALCDFEMNDANSSVKIEHDYDCVIFGAVGDILGNYKETISKLLPTIKSKGFILIDDAY
                     VVDKSTNEQLNFERVYPTYNEWCILFKELGLKLIECIPCLELENDVEEEMNWIITRAN
                     ELIKKYPSQKDMFEQYVISQKNEYTDLQQDLVGATWILQKE"
     gene            complement(22501..23151)
                     /locus_tag="KR231_002504"
     CDS             complement(22501..23151)
                     /locus_tag="KR231_002504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0004868.1"
                     /translation="MNIVMINGSPKVNKNNSQYFLSELKQLIQNDNKVFTFKVDNTSK
                     YPDALNAILNCDRLIIASPLYVDGIPSHLLHFLEKCEKFLKTQNKKPIPVYAIVNCGF
                     NEGEHNHLAIQMIEHWCKKINFTWVQGIGIGAGEMFGSLESVPLGKGPKKDLGIALKE
                     LSKNILSDNIHIDDSNKSTIFISPNFPRFLYKLMGNHQWNTQAKSNGLTKSDILKK"
     gene            complement(23148..23651)
                     /locus_tag="KR231_002505"
     CDS             complement(23148..23651)
                     /locus_tag="KR231_002505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin family protein"
                     /protein_id="HBH0004869.1"
                     /translation="MRLLIHDLTDKELEKLLPKLDDNIKILPNTKEIHKCIGCFGCWI
                     KTPSECVVKDYYSNMGKLINDSDGIIIISRCCYGGFSPFVKNVLDKSINYILPYFVIK
                     DNMMRHKSRYDKQINLKAIFYGDCITEAEKETATKLVNGNAINFNIKEHSVCFYENIQ
                     DIRGESI"
     gene            complement(23700..24215)
                     /locus_tag="KR231_002506"
     CDS             complement(23700..24215)
                     /locus_tag="KR231_002506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HBH0004870.1"
                     /translation="MLEYIILGFLMEKELSGYDLKQIMSESTSYFFDASFGSIYPALK
                     RLETKGYIHYHEVIDGNKLKKLYSITNTGKEVFLEWLKKPINFSKTKQDHLVNIFFYK
                     YLPKEIIETNLKMLITEVELLLNKLSKQKNDAEENHCVDQYTYMYATMIYGVDYYNFV
                     INWCKDLLKNL"
     gene            24495..25019
                     /locus_tag="KR231_002507"
     CDS             24495..25019
                     /locus_tag="KR231_002507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HBH0004871.1"
                     /translation="MHEQIDCCERKKRTIDIKGENMRELLKWVSIINRYNTNYIDRKL
                     ADIGINNSQYFYVLHICNNPGITQDTIFEKILVNPSNITRALANLEKEGFITREPGVK
                     DKRTWHLYPTEKSLGCYDEILKITNGYVEELLSSFEKEEQELFMSMLKKVAFLAIDMN
                     EEAKLEAKENGRKI"
     gene            25003..26406
                     /locus_tag="KR231_002508"
     CDS             25003..26406
                     /locus_tag="KR231_002508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HBH0004872.1"
                     /translation="MEEKYKEPLEYEKVSKLLTKYAIPSIIAMLVSALYNIVDQIFIG
                     QGVGVLGNAATNVTFPLTTICTAIALLLGIGGASKCSLELGAKNSEKATKAAGNSICL
                     MAVFGISLFIVVSIFLTPLLKFFGSTSEILPYAHTYTKITSIGLPFLIMSTGMSKLIL
                     ADGRPKASMFCMLIGAVINTILNPLFIFVFNMGIAGSALATVIGQLISFGISVHYIKN
                     FQHIKLHKKSFKLDSIIYKHIFALGSSSCFNQLAMTVTQIVMNNTLAYYGARSVYGSE
                     IPLACVGIIIKVNMIFISIIIGISQGMQPIIGYNYGAEKYNCVKEAYKFAVGSATIIS
                     VIAFLCFQLFPRQITSIFGNGNETYFIFAEHYFRTFLFLTFINGVQIVSSTFFTSIGK
                     SVLGLFTSLTRQILFLIPLIVILPMFMGIDGVMFAGPIADAAAAMVCIYFAVHEMKSL
                     TIKQNNLMSNHNKIAEV"
     gene            complement(26970..27281)
                     /locus_tag="KR231_002509"
     CDS             complement(26970..27281)
                     /locus_tag="KR231_002509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0004873.1"
                     /translation="MKKIIKSFTFWFFLIALFEIYMHQIGQDSKSIVLIGLNPILSII
                     SRVDSFFVFMDSGMQIPCRTITGSISIYWYIASILSFLIYGIILDLIRIVISKIGNKT
                     K"
     gene            complement(27337..27930)
                     /locus_tag="KR231_002510"
     CDS             complement(27337..27930)
                     /locus_tag="KR231_002510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HBH0004874.1"
                     /translation="MISDSISKRRSIRKYKNQSISHETIEKIIEAGINAPSSKNRQPW
                     RFVVITEKEKESMLKAMSKGIQNEINDNGLLPGSRQHIAGANYTVEIMKQAPVTIFIL
                     NILGKSPLEKLSPEERFYEMANMQSIGAAIQNMSLTAVELGLGSLWICDVYFAYRELC
                     EWLNTDSQLVAAISLGYPDEEPSRRPRLQLSDVTEWR"
BASE COUNT        10562 a         3469 c         4630 g         9756 t
ORIGIN      
        1 gaaaagacta taaaataata aacaatatga tttcatatac caataaataa gataatattt
       61 aagaaaaatg attatattta aaaggtaagc ataaaattta taaactttta gaatagaaat
      121 ctcaatcaat tagatattca aattgatgaa tatgaatacc taaatagatt gagatttatt
      181 atgtacaaaa cttatcctaa tatatctgac attttataaa gcccagattg cttaccaatt
      241 aaaaatttag ctgcaactat agagccgttt gcaaatactt catcagattg agaatgatgg
      301 cttaatgtaa gaacttcatt atcacctgca aatacaacat catggtcgct gattatattg
      361 ccacctctta tagagtgtat tccaatttca tttggttttc ttttacaatc tctaccatat
      421 ctaccatgtg tattttcact ttcaggcaag acttctctaa ttgcattagc tatcatagta
      481 gcagttccac taggggcgtc ttcttttcta ttgtgatgtt tttctatgat ttcaatatca
      541 aaaccttcta acatctttga agcatcctta actaatttta ttaatatatt tactccaaga
      601 gatgtatttg atgataataa tataggaatg ttttttgatg cttcttctat tttatttaag
      661 tcattttcgt catatccagt agtagctaat actacaggtg tattattttt tagagcatat
      721 gacaatattg gctctaaagt atcatgatgt gaaaagtcta taattacatc agttttttca
      781 gttacatcag tcattgtttt gtaaagcttt gtatcactat gatgaccttt ttcatcagca
      841 gacctagcta caccacaaac caactctaat tcattatctt tttttacaca ttctgctaaa
      901 actcttccca ttgttccatt atagccacta attataactt tcaacataaa ttcctcctat
      961 gaaattaata aaaatttgtt atatttctat aagtttattt tatcactaat ataatttata
     1021 taaaataata ttagtgataa taagcttaca atttatctta cattaaaaaa tttaagtgga
     1081 tttttcaaaa tatagataaa tttctttttc attgtttaaa tgataaaaat atatttgact
     1141 tcataccaaa aagagtgccc catgaactaa aaagttaatt ttgaaatacc atattcatat
     1201 atcatatgat ttatttggaa attaatatta atacattaaa ataactaaat acatgtatgc
     1261 ataaagatgt ataaaaaata tataaacata tagtattaat tttaaattca acaatttaat
     1321 tgttaaaagt gttattatta aattagaaat atcttaactt aatatactga gatgggagtg
     1381 atagatatgt taaaagaaga aaaaacttat caagagaaag acgcaaaagt attcaatgga
     1441 gtggcagctt tgataatgat tttattattt ttagtagttt caataggtat catggttttt
     1501 gggatagtaa aacttgatag tggatttact ggaataggtt cacttatgtt aattttggga
     1561 cttgtattta tagtagtaga ttttatccta ttttttgggc taaaaatgat taatcctaaa
     1621 gaagctatag ttctagtttt gtttggtaac tattatggaa ctataaaaaa agaagggtac
     1681 tattgggtga atccattttg ttcagcaata aacccagcag tatcaagaat taatgtatcg
     1741 aaatcttcat ctgatgaaaa ggtagatata tcaactaatt caaggggcaa aaaagtatct
     1801 ttaaaaacaa tgactcttaa taatgaaaag cagaaagtca atgatttatt gggaaatcca
     1861 attataatag gagtggttgt aatttggaag gttatagatg caacaaaggc agtatttaat
     1921 gtggataatt ataatacatt cttatctatt cagtgtgatt ctactattcg caatgtttca
     1981 agactttatc catatgatgt atctgaagat ggagatgaaa aatctcttcg tggtagtagt
     2041 caggaaatag cagatagatt aaaagatgaa ttacaatcaa gggttgacat tgcaggaatt
     2101 gaagtgtgtg aagtgagaat tactcatctt tcttatgcac cagagattgc agcagcaatg
     2161 ttacaacgtc aacaagcaga ggctataata gcagcacgta aaaagattgt tgagggggct
     2221 gtaagtatgg tagagatggc attgactaat ttaagtgaaa ataatgttgt gactttggac
     2281 gaagaacgta aagcagctat ggtaagtaat ctgttagttg tgctttgtgg caataaagat
     2341 gcacaaccag tggtaaacag cagttctatt tattaaatta taaaaagttt aatagtttat
     2401 tttattgata tatagaaaat ttagtagttc attttattaa attatataaa gattaatggt
     2461 ttgctttatt gaattataaa aagtttaata atttattcta ttgatatata gaaaatttag
     2521 tagttcattt tattaaatta tataaagatt aatggttttc actttattaa attataaaaa
     2581 gtttaatagt ttattacatt gatatattga aaaattgaag gaaataaaaa tacttgtcag
     2641 caagaaataa aaatgatata agaatgaata agagaattgt aaaaaaataa aatgattata
     2701 aataaaagat aaaaatattg taaaaaagag ggtgcctctg gtgaattaaa ttcacacaga
     2761 gacacctttt taattaattt tttaaattag tatattattg tttaattaat agcatagtac
     2821 tatttaatta atctaaattt ctaaggtctt ccataagctt agttttgtca gccgtttttt
     2881 catctttcat ttttataact ttagcaggag aaccagcaac aacggcacca gcttctacat
     2941 cagtagttac aacagcacca gctgcaacaa cagcaccttt accgattcta acaccttcaa
     3001 gaataactgc attagctcct attaaaacat catcttcaac tataacagga gtagcagaag
     3061 gtggctctaa aacaccagca acaacagcac cagcacctaa gtgaacattt ttaccaagag
     3121 ttcctctagc tccaataaca gcattcatat ctaccataga accttcacca ataacagctc
     3181 ctatatttat aacagctccc atcattacaa cagcattttt ttctatagta accatgtctc
     3241 ttattattgc acctggctca attcttgcat gttcacttaa agtatttttt agaggaatag
     3301 cagaatttct tctatcatat tctacatgag tatctgttat atcatttcca tgtttatcta
     3361 atacttccat tatatcctca tagtcaccta caaatatata agaaccatta cttccaaata
     3421 ccttaaattt atcagttgat tggaagtgta aagagttagt atttacatat accttaacag
     3481 gtgttttctt tttaacttct tttatatacc ttgctatttc ataagcatcg tttaaattta
     3541 ccatttgtta attctccttg tatttcatta tatttctttt attatatact tatttgtcaa
     3601 ttttagtata tacttacttc ttattattta tattttattt tagttagctt ttattgtata
     3661 gacatagtat taaataaatt tattatatat gtttgatttg tattgcatat tattatatat
     3721 atattgtata tgtttaattt atattgtgta ttattatatt tatactatta tcccaacatg
     3781 ctgtccatat tataaaatcc tggtttttgc ttaactaagt atttggcagc agctatagaa
     3841 ccacttgcaa agataccacg agattgagct tgatggctta ttgtaagaac ctcattgtct
     3901 ccagcaaata gagcatcatg ttcgccaaca atatttccac ctcttatagc atgaatacca
     3961 acttcatttg gttgtctttt tgcactacga ccatatctac cataattatt ttcaacgttt
     4021 ggcaaaacct cttttatagc gttagcaatc ataacagctg tgccacttgg ggcatctact
     4081 tttctgttgt gatgtttttc tattatttct atatcaaatc cttctagtaa tttagctgca
     4141 tctttaacca attttactaa tacatttaca ccaagagaca tattatatga ttggaataca
     4201 ggaataactt tagccgcttc acgtattttg ttcatttcgt catcattata tccagtagta
     4261 gcaattacta aaggtgtttt agtctttaaa acgtaagata agatattatc taaattagag
     4321 tgatgagaaa aatctataac tacatcagct tcctcaacta tagtactcat atcttcataa
     4381 attttaaggt cgccttcata gctatccaga cctctagctg caacacaaac caattctaat
     4441 tcattatctt ctcttatagt atcggctaaa atcttaccca tttttccatc ataaccagtt
     4501 gctataactt ttaacataat ttcctcctat gattaagggc taacttttga ccaaacttac
     4561 tttttaccat gcattaatct ttactatgca ttaactttta gtccaaagtt aactaattct
     4621 ttctttaata cttctaaatt tgctgggtcc atttctgcta gaggtaatct taaatctcca
     4681 acattgaatc ccaataaatt cattgcagtc ttaactggta taggatttac ttctataaat
     4741 aaagctgcga ttagagcatc cataccaagt tgtaattttc tagaaccttc aatatcgcct
     4801 tcaaagaatt tagctaccaa atcgtgagtt tcttgagggc aaacattagc aagtactgat
     4861 ataactcctt gacctcctaa agataataaa ggaagtatag tatcatcatt accagagtag
     4921 atagcaaagt catctggaac taaactagct atttctgcaa cctgtcctag gtctccacta
     4981 gcttctttta cagcaactat gttatcaatt ttagcaagtt caactataag gctaggactt
     5041 atatttacac aagttcttcc agggacattg taaagtataa ttggaagttt aacactgtta
     5101 gctattgttt caaaatgacg cttaagtcca gctttattag ctttattgta ataaggtgtt
     5161 attattaata gagcatctac tcctaatttt tcagcttctt gacttaagtt aactgagtgc
     5221 atagtatcat tagaaccact tccagctata acaggaactc ttttattaac tttttcaaca
     5281 acatacttaa tagtagcaag ttgttcttca tcagtcatag tattagcttc accagtagta
     5341 ccacaagata ctatagcatc agtaccatta gctatttggt attcaactaa ttcacctaat
     5401 ttgtcaaaat caactttgtt atcctttgta aatggtgtaa ctagagcaac agcagaacct
     5461 ttaaatatca tataaaatca atcccctctt ttttattttt gtgttttata ttacagttac
     5521 ttctaatgct tgtttttgag ttactattaa tattttacaa aattatatat ttatacaagt
     5581 ttgtatatta tactaaatcg tatgataaag ccatttcagc tatttgaatt gcgttagttg
     5641 cagcaccttt tcttatatta tcagcaacaa cccaaagatt tacaccatta tcaacactaa
     5701 aatctcttct tattcttcca acaaatactt catctctatc atcaaattct acagcagttg
     5761 gatattcgtt tttagcagga ttatcaacta ctacaacacc tggagcttct tcaagtgttt
     5821 ttactaaatc atctaactca aatggattgt taaactcaac atttatagat tcactatgac
     5881 cattttttac tggaactctt acagtagttg cagttatttt taaatcgtag ttatcaagta
     5941 ttttcatagt ttcatttacc attttcattt cttctttagt gtatccattt tcagtgaatg
     6001 aatctatatg aggaagacag ttgtaagaga tttgatgagg gtagaatcca gtaggattac
     6061 cgttcattcc tttctctaaa tcttcaacac ctttaacacc agaaccagat acagcttggt
     6121 aagtagagta aacaactctc ttaattttgt atttatcatc aagagcttta aggggaacca
     6181 tagcttgtat agtagagcag ttaggattag ctattatacc cttatgattt tttatggctt
     6241 ctggattaac ctcaggaact actaaaggca catctggatt cattctccat tgactagagt
     6301 tatctactac taagattcca tttgaagcag ctattggagc atacttttca ctaatacttc
     6361 caccagcaga gaataatgct atttgtatgc ctctatcagt aaatgaagtt tcctttaatt
     6421 cttctactat atattcttta ccacaaaaca ttactttaga accagctgat ttagaagaag
     6481 agaataaaaa tagattttct attggaaaat ttctttcttc taatactttt aaaaatgttc
     6541 tacctaccat tccagtagca ccaattattg ctacatttac ttttttcata taaattcacc
     6601 ccaattttaa attattaaaa cattatttta ttttagttat acaagtaaga tatgttaata
     6661 tttttatata tccaaaaact ttaatattat attaacaact ttaattatat acaaaaaacg
     6721 tacaaaggta tactttgtac gtctaattta tcactcaaag taaaccctgt agctcatcac
     6781 ctacaaaaat aagtgacagt attacacatg ttatgtgcaa tcccagaaaa tattattgca
     6841 agaaatattt tcttcggctg taaatccttt ttccaatcat taacacctgc cagctactat
     6901 tggatactct tagttacagc tacctctacc ctaggttaat aggatattaa aatttgatta
     6961 ttctaataat aatacatatt taagaaaaaa tcaacttatt tatataaata ttgctaaaat
     7021 ttaaatccaa aatttgtcaa ttcttgtttt aacacattaa gattagtttc ttccatttca
     7081 gctagaggaa gtcttaaatc accaacatta aaacctaaaa tgttcatggc agttttaaca
     7141 ggaactggat ttacttctat aaataaagca gcaattaaag catccatatc aagttgtaat
     7201 ttttttgagc cttcaatatc accttcaaag aatttagtta ctaaatcatg tgtttcttta
     7261 ggacatatgt tagcaagtac agagataata ccacttccac ctaatgataa tagtggtagt
     7321 atagtatcat cattaccgga gtatatagca aagtctttag gtactaattt agctatttct
     7381 gcaacttgag ctaagtctcc acttgcttcc ttcacagcaa ctatattatc tattttagca
     7441 agttcagcca caacagatgg ctttatattc actttagttc ttcctggtac gttgtataaa
     7501 ataattggca acttaacgct atttgctatt gtttcaaagt gaagtttaag acctttctca
     7561 ttagtcttat tatagtaagg agttattatt aaaagaccat ccacccctaa tttttcagct
     7621 tcttgactca tatgaacaga caacatagta ttgtttgaac cagtacctgc tataacaggt
     7681 attctcttat taactttttc aactgtatat tttattacag caaaaatttc agattcactc
     7741 atagtagtcg cctcacctgt tgttccacaa acaactagtg catctgtgcc attctcaatg
     7801 tgatattcga ttaattcacc taatttttca aagttgacat tattatcctc tgtaaatggg
     7861 gtaactaaag caacagcaga acctttaaat aacatataat caaatctcct tttttatcta
     7921 aatttaattt tttaagtaca ataataatta tagtacaaat taattaattt taataggtat
     7981 agttaatatc ttaactgttt aaataagata tttatattat attaatatta gaaaaatttt
     8041 aaataaatgt tttattctca aaatatgcat attaatttaa taaaatatac caaaatggaa
     8101 ataaaaaata aattttatga gaatttaata actaataatt aatatattta ggttataata
     8161 aatatgtgcg taaaatctaa caataagcaa taataccgta aatttaggag gaataatatg
     8221 gatactttaa aggaactttt taaaatagga agtggacctt caagttctca tactatggga
     8281 ccacaaagag cagcagagag atttaagaat gaaaacccag atgcagaaag ttttagagca
     8341 atattatatg gtagtttggc agctacaggg aaaggtcact taactgacta tataattgaa
     8401 aaaactatag cacctaaaaa agtcgaaatt gtttgggaag aagatattat aaaagatttt
     8461 cacccaaatg ggatgaagtt tgaagcttta gataaagata aaaatgtaac agctgaatgg
     8521 actgtatatt ctgtaggtgg aggaactata gcagaagaag gtcaaagaaa cagtaaaagc
     8581 aatagtatat atcacttaga tactatggat gagatagtaa aatggtgcaa agaaaataat
     8641 aagactttgg tagattttgt gttggaatgt gaaccaaaag acataaaaga ttatataaaa
     8701 actataaaag atgctatgag aaaatctatt gatgatggac taagtacaga tgaaataata
     8761 ccaggcaagt tattattaaa aagaagagca agtacatttt ataatgcata taaaaaagat
     8821 aagagcttct caacacttgt atatgcatat gcactagcag cttcagagca aaacgcttct
     8881 ggtaatataa tagttacagc accaacttgt ggttctgctg gagtaatacc aggaatattc
     8941 tttgcaatgc aggatttcta taattatgat gacgaaaaaa taattgaagc actacttgta
     9001 gctggaataa taggtaatat aataaaaact aacgcttcaa tatctggagc agaggtaggg
     9061 tgtcaaggtg aagttggagc cgcttgttct atggcagcag cagcagtagc atacttaaaa
     9121 ggtggaacta tagaccatat tgaatatgcg gcagaaatag cacttgaaca tcatttagga
     9181 atgacttgtg accctgtata tggatatgtt caaattccat gtatagaaag aaatgcaatg
     9241 gcagctcaaa gagcttatga tgcagctaat tatgcattat taactgatgg ctcacattct
     9301 gtctccttag accaagttgt tgaaacaatg aaagaaactg gtatagatat gatggataag
     9361 tacaaagaaa cagctaaggg tggacttgct aaacatttct tctcttgcta aaaataaaat
     9421 tttccaataa taattcctct gttttgattt atgaaacagg ggaattatta ttaatggtga
     9481 attatttaat aatgcaaaat atttttatat tcaatttagc tttttatttt taattagtat
     9541 aacatgctat ataatatttt aattataaag aaatatagaa atatttttta ataaattaga
     9601 aattggagga gattacatga gagaggcatc atatttacaa gaacaacttt ataaacatag
     9661 gaagtcatta aatcctattg cagagattgg gagaaaagag tataagactt caaaatatat
     9721 aagagattat cttgataaat taggaattga gtatgaagtt tatttagaaa caggtatagt
     9781 aggtgtaata gaaggtaaaa gacctaaaaa agatattgct tttagagctg acatagatgg
     9841 tcttcatagt gaagaagggg taaaacattt atgtggtcat gatggacatg ctactatctt
     9901 acttggatta attgagtatt taaatgataa taaagaagac ttaaatgata atatagtatt
     9961 tatattccaa ccggcagaag aaggtcctgg gggagcaaaa gctttaatag atgaaggagt
    10021 gcttagaaaa tacaatattg atgaaatata tgggcttcat atatatccag agttaccaga
    10081 aggttatgta ggtacaagag agggctattt tatggctcaa ataggagata ttgacataga
    10141 aatagtgtct aaaagtggac atggggctat gccacaaaat ggtattgatg gtatagtgat
    10201 agcttcaaac tttgtaagct cacttcaaac tatagtgtct agaaatataa gcccaataga
    10261 caatgcagtg ttgactattg gcagaattga agggggagct agaagaaata taatagctga
    10321 aaatataaag atggaaggta ctatgagatg tttcagccca gaagtgtatg agaaaatgaa
    10381 gcttagagtt agagaacttg ctagagggtt tgaattggct tataactgta aggttaatat
    10441 aaatattata gatgattata tcgctgttaa aaatgacaag gatttgtatc aagagtttgt
    10501 agaggctatt ggaagtgata ctgttgtaga gttagagcca cttatgatat cagaagattt
    10561 ttcttattat caaaaagaag ttccaggatt attttttatg ttgggttcaa gaaacgaaga
    10621 aaaaggattt gtaaatggtc ttcataatat aaactttaat tttgatgaaa agatatgtgt
    10681 aaatgcattg aatgtttatt caaaattatt aaaatacaaa gaagcaatag attaggaaga
    10741 taagttataa agattaaaaa gcataaatac ctaaatttaa aaaaagtgta ttaataaata
    10801 ccccttacat atttgtataa atttatttta attgacaaaa atacaaataa gaaggggtga
    10861 tttttttgaa agaaaaagta caaagagaaa agaagataac taatggcaag aatactaaaa
    10921 tattgacaaa tgatgatata atgaaatatg agatagcctc agaactaggt cttatggata
    10981 aagttggtga acgtggatgg gcaggactta cagctaagga agcaggaaga attggaggta
    11041 tgcttacatc acgcaaaaag aggcttaaaa agattgtgga ggagcagaat aaaaaggatg
    11101 agtcaatata gtgattttgc gtttgtatat gatgaactta tgaatgaagt tgattataat
    11161 ggttgggtta aatatataga agatataata gatagtgaag gtgtaaaagt aaaaaatata
    11221 ttggaattgg catgtggcac gggtaatctt acaattccat tgactaaaaa aaattacgat
    11281 atagctggta tagatatatc tgatgagatg cttagtgtag caagagaaaa gtcagaaaaa
    11341 gaaggagtag aattagtttt acttcaacaa gatatatcag agcttgattt tgaaatatct
    11401 gatttggact gtgtactttg tgcttgtgat ggattcaatt atataactta tgatgatgat
    11461 ttggaaaatg tattttcaaa gacatatgaa ttattaaaga aagatggaat attcatattt
    11521 gatataagtt ctttttataa attagccaac atattgggaa ataacatgta tggagaaaat
    11581 agagaagata tagcgtatat gtggcaaaat tactttgatg aagaagagaa tctaattgaa
    11641 atggaactta cattctttat taaagatgaa tgtggaaaat ttgaaagatt tgaagagata
    11701 caccaacaaa gagcatatac tgaagatgag atagttgata tgcttgaaaa atctggattt
    11761 aaggatataa aatattatgg ggattttaca tttgacaaac ctagtgaaga aagtcaaaga
    11821 atcttctttg tatgtaaaaa ataagatatt tttgactata taagataatt attaaaaata
    11881 accatgatat aaaaatatag aaaatgcagt tttatagatt aaaagtaaag tgatgatact
    11941 ttatgacttt tattttttaa taattataaa gttctataga taaaaattaa aatataataa
    12001 ctattgctta gtaaaattaa aataaaatgg gttttgccca aggttaagat agataagtat
    12061 ttatagatta aaattaaggt agtaatataa taaaaataag acaattaacg ggacatggag
    12121 gaatattaat gagagattat gtactaagag cgacatcagg aaatggtcaa gttagagcat
    12181 ttgtcgcaac tactagaaat acagtagaag aagctagaag attacatgaa actacaaaag
    12241 tagcaacagc agcacttgga agaacattaa cagccacatc tataatggga ttaatgatga
    12301 aaaatgatag tgataaattg actgtaataa taaaaggtgg aggtccaatt ggaactatta
    12361 tcgccacatc agactctaag ggaatggtaa aaggatatgt aggaaatcca caagtagagg
    12421 ttgaagacta tccaaatgga aagttaaatg tagcagcagc agtaggtaca gaaggtgttg
    12481 taaaagttat aaaagactta ggtcttagag aaccatataa tgggacttat ccattggtaa
    12541 gtggagaaat tgcagaagac tttacttatt attttgctgt atcagagcag actccatcag
    12601 tagtagcttt aggtgttctt acaaaagaag atgaagtaga gtttgctgga ggatttatag
    12661 ttcaattaat gccagatgca gaagaagaga ctattgctaa gttagaggaa aatgtagcta
    12721 aattaccttc tataactaac atgttaaaag aaggaaaatc accagaggat atattaaata
    12781 ttgttttgga tggtttggaa cctaaaatac ttgatacctg tgaagttggg tttatgtgtg
    12841 aatgttcaaa agaaagagta aaaactgctt tggttgcaat tggtaaaaaa tcattggctc
    12901 aaataataga agaagataaa aaagcagaag ttggttgcca gttctgtaat aagaaatata
    12961 tgtatagtga agaagagttg cttgaaattt taaaggaaat gtagactata aaaatagttg
    13021 tattgatata agtaatgtta tagtgatata gtaaagtcgt attgatatag taattaaagt
    13081 ataatttatt aataatagac atatttatat taaaaaataa gtttaataaa tttttaagct
    13141 taataaattt taagaattaa gaagctttct ggctgtaatg tttgcaatgt tgcagttaga
    13201 aggctttttt attttattat agttcgtgtc aaagattgta tgaaacaata aaatattgta
    13261 aaataatttg tatatttaga cctgattggc acaaaggttt ataaggtatt tgagttgatt
    13321 atgcgaaatt ctatgaagta gtaaccctgt gactttaatc atgggaggtt cagaagaagg
    13381 agaaaatttt aaatatggaa agtaaaacga agtacatagg aataagtata ttaatattat
    13441 tgatgatatt tttaattgca aaaaatttta acggaaaact tgaaatacct attcctgaga
    13501 gtaatagtag aaaatttaaa tcagcagcag tgttttatcc tcaacatcaa gatgatgagg
    13561 ttttatgggg aggaagtgcc attgtagatg ctataaaaca gtgtggtgtt gataatgtat
    13621 atgtggtatt agtatcagat ggttctggag ttaacgtttt caaagctaac acaaaattta
    13681 gaaatttaac taggaagcaa aaggaagaac ttagaaataa cgagtttaaa tcagctttga
    13741 gagagcttgg agtgaaacct caaaatgtga ttatacttgc agatatagat aaaaaggaag
    13801 gcacacatta tgaattaatg gaaaagacta tattggattt tgaacataag tttaaaggca
    13861 atgtgaccca tatagcccat cactataagt atgatgacca tataatgcat agaaagaatg
    13921 gggaagtttt aaagaaactt aaacgtgaag gtaagataaa agatgacttg tattttgtta
    13981 agccaaaata tgtaaagtat ataccaagaa atgaaagagc tatctataaa gcaatggatt
    14041 ttgatgacta caataaggtt aagagtgctt gttatgaata taaggttgta aattcaaagc
    14101 gtaaaatgta tggtatagga tatatttcgg cacatagtta ttttgaacat cttctaaatg
    14161 accctgaact tacgtctgta ttaagtgaag attaatttct tataagtagt aagttatgtt
    14221 tgataagttg attggaattt tctatagttt tgaaggtatt ggaaatttag ttttatttaa
    14281 agatttaaag atagaggttt ttagtgttta aaattttaaa gttaagttga ataattgtat
    14341 agaattattt gtgaaagaag aaacagtgta aaacatagta tcttatttat ggttttaaaa
    14401 tcataggcaa gatacttttt ttatgtaact aataccattt tgagattatt aacttaagaa
    14461 ttttatataa tttaacactc atatataatg atgatattta ggtagaatag atgcaattac
    14521 gcttaaataa aataactgta ttttttataa aaatcaaacc ctacactata ctaccagata
    14581 aaatctacat gctataattt gacctgtgtt tataaaaaaa ggagtaatct aataaaatag
    14641 tatttcactt atgtataact aacaactatt attacgattt tctctaaata atttaaagaa
    14701 aaataatgca ggaggtaaaa tatgaacaat gaatttataa ttttaaaagg ttgcaaagag
    14761 aacaatttga acaatatttc cttaaaaata ccaaaaagaa aaataaccat attcacaggg
    14821 gtgtcgggtt ctggaaagtc atctattgta tttgagacaa ttgcaaaaga atcacaacgc
    14881 caactaaatg aaaggtttag tacatttgta agaagttttt tacctaagta tggagaggtt
    14941 aaagctgatt gtatagaaaa tttgtcaaca ccaattatca tagaccaaag tagacttggt
    15001 ggaaattcaa ggtcaaccct aggtactatt acagatgtaa attccttttt aagagcttta
    15061 tattcaaggt ttggtagtga gtatataggt aatgctaata tgttttcttt taataatatt
    15121 gatggtatgt gcccacactg tcatgggctt ggaaaaaagc tagttcctaa tatgaaccaa
    15181 attcttgata tgaataaatc attaaatgaa ggtgctatat tgctttcagg gtttggagtg
    15241 ggttcttggc attggaatat attcgctgaa tcaggatttt ttgatattaa taagaggata
    15301 tgtgattatt cagaagtaga attggaaaag tttttgcatg gtaaagcaga aaagattaag
    15361 atagaaaatg ctggtcaaac taacatgaca tatgagggat taatggttaa atttaatcgc
    15421 ctatacttaa gtagagaggg agaaatatct gaagctacta agaaaaaatt gagtaaactt
    15481 cttatagaag atagatgtcc tatatgtgat ggaagaagac ttaatgaaag agtatatagg
    15541 tctttaatta atggttataa tatagcagat ttaactagta tgcaaattga tgaattggct
    15601 gaagttatta aaagtataga tgagccagaa gcacaacctt taattaaagg aataatagaa
    15661 aagttaaaca gtatcataga tataggtctt ggatatttaa cactggatag agagacatct
    15721 tctctatcag gaggggaatc tcagcgtata aagatggtta agtatttaaa tagtaatctt
    15781 gttgatttaa tgtatatttt tgatgaacca agtgtaggac ttcatccaaa agatgtgtat
    15841 aaattaaata atcttttaaa aaaattgcgt gataaaggga atacaattat agttgttgaa
    15901 catgacccag atgttattaa gattgcagac catattgtag atgtaggacc aaaggcaggt
    15961 aagtatggtg gagaagttgt gtatgaaggc agttatgaaa atctacttac aagtggtact
    16021 ttgacaggga atgctttaag taaatttctt cctattaaag aaagtgtaag agaacatagt
    16081 ggatatttag aagttaaaaa ttgtaataaa aacaatttaa aaaatgtatc gattaagata
    16141 cctaaaggtg tattgactct agttactgga gtagcaggag caggtaaaag tacgttgatt
    16201 aaggatgaat ttttaaagca aaatcctagt gctgtactta tagaccaaag ccctgtttca
    16261 gcaaattcaa ggtcgagttt ggcaacatat agtggaatta tgaacaacat aagaagcata
    16321 ttttcaaaaa caaatggcgt aaatgcttct ttattcagtt caaattcaga aggagcttgt
    16381 gataactgta agggttctgg aatagtagaa atgaatcttg cttttatgga gagtataaag
    16441 agtacctgca atgtttgtga aggtaaaaaa tttaaaaaag aagttttaga atataggttt
    16501 caagggaaga atataattga agttcttgaa atgtctgttt tagaggcaat tgagtttttt
    16561 aatttaaaac agattaaaac gaaattacaa tgtattgaaa aaatgggtat tggatacctt
    16621 actttaggac aaactcttga tactttgtct ggaggagagt gtcaaagatt aaagcttgct
    16681 agtgaattaa ataaggaaag ttcagtgtat atattagatg aaccaacaac aggtcttcat
    16741 atggctgata ttgagaattt tataagtata attgaagaga ttgtagataa tggaaatacg
    16801 gtcataataa ttgaacacaa tatagatgta attaaaagag ctgattggat tattgagctg
    16861 ggacctgaag gaggaacaaa aggcgggaga gtaatatttg aaggtattcc aaaacaatta
    16921 tgtaacaata aaatatcatt aacagcaaaa tatatagtat aataaataaa atataataaa
    16981 attataatga tattttaata aatataatgg gtatataaaa tgataattaa acttaacagt
    17041 aataaataat gtgagaaata ttcaaattta attaaataaa gtgtcagaaa tttgtttaaa
    17101 ttttagtatt ttaacggttc tgaccttttt tcttattttt atggagaata tcgaggatgg
    17161 agtctctaat agttactttt ttgtgtctac ttgcaagttt gattaaaaaa tggctataca
    17221 cacttgtgac ttcagtcatg ggaggttcag attataatct taatatataa tttgtgaaat
    17281 aatttgatga cgatttgctg atgtataaac aataaagatt aactacatta aaatttaaat
    17341 cttgttaagt aaaacttata aaaggagaga gatggatgat aaatgatatt ctaaccttat
    17401 tatctgaaag aagtgatttt tttataaagc tatccataga acatttgatg atttctatta
    17461 tttctataat aattgcgatt gttttgggtg gtataattgg tattattgta agtgaatttc
    17521 ataattcttc taaacctata ttgggaacta tcaattttct atacaccatt ccatctattt
    17581 ctatgctagg atttctgata ccattttccg gaattggaaa tactactgct gttattgcac
    17641 ttaccattta tgcattattg ccaatggtta gaaatacata tactggaatt actaatgtgg
    17701 ataaaaatat tcttgaagca gctaggggaa tgggaagtac agattttcag atattgtata
    17761 aaataaaact tccgttagcc ctacctgtta ttatgtctgg tattagaaat atggtgatta
    17821 tgacaattgc attagctggt atcgcttcat ttataggtgc tggaggtcta ggtgtagcca
    17881 tatatagagg aatcacgaca aataacacaa taatgacaat tactggaagt atacttattg
    17941 ctctattagc tttaatattt gattttattt tagggctggt agaaaaattt tttcaacgaa
    18001 aaagaaaaaa gaaaaatagg aaaaaagttt ttgccattct aggaagcctt attcttatag
    18061 caactatctt tacgtcttat ttatttaatc cttcaaagac tcaaactatt catattgcta
    18121 ctaaacctat gactgaacaa tatattcttg gtgagatgtt ggatatttta attgaaaaaa
    18181 acacaggtct aaacgtggaa attacacaag gtgtaggagg gggaacatct aatatccagc
    18241 cagctatgga gaatggagaa tttgacattt atccagagta tacaggtaca ggctggaata
    18301 tggtacttaa gaaaaatgaa ttatatactg aaagtatgtt tagtaaacta cagtcggaat
    18361 acaaaactaa acttaaaatg caatggactg gtatgtatgg tttttctaat agctatgcat
    18421 tagcagttag aaaagaagtt gcagataaat acaatttaaa aaatataacg gacttaaaag
    18481 atgtatcttc taaattgaca tttggagctg aatatgactt ttatgagaga gaggatggat
    18541 atactccatt gtgtaataca tatggactga actttaaaga tacagttgat ttagatattg
    18601 gattaaaata ccaagctatc aatgaaggta agattgacgt aatgcctata tttacaactg
    18661 atggtcagta tagtgtttca gatgttgtag ttctaaaaga tgataaaaat ttctacccat
    18721 cttatcaatg tggaaatgtt gttcgtttgg aagtattaga ggaaaatcca gaactatcaa
    18781 aggtatttaa gatggttgga gatattttga ctgataaaga aatggctaaa atgaattatg
    18841 acgtagaaaa caacaattta gaacctagag aagttgctcg tgagtttctg aataagaaag
    18901 gtcttttata aattggagga aatataatga cacctattat acaatttaaa aatattaaaa
    18961 aacaatataa tgataaaact ataatagata atcttaattt agatatagaa aaaggagagt
    19021 ttttgactgt aattggttcg tctggttctg gtaagacaac actcttaaaa atgattaatg
    19081 gtctgatttt gccagatgga ggaaatattt tgataaacca aacagatatc aaaaacgagg
    19141 acttaattaa attaagaaga agaataggat attgtgtaca gggaagtgtt ctttttcctc
    19201 atatgactgt tgaagaaaat atttcatatg taccaaatct cctaagtaaa aagaataaat
    19261 tagaagtaaa aagtgctgta aacaagtgga tggaaatagt gggattgcca aatgatatga
    19321 aagtgcgtta cccatcagaa ttgtcaggtg gtcagcaaca acgtgtaggg attgcaagag
    19381 ctttagcttc ttctccagaa attttattaa tggatgaacc ttttggtgca gttgatgaga
    19441 ttacacgaaa gcaattacaa aaagagataa aagaaattca taaaaaaaca ggagttacaa
    19501 ttatctttat tacgcatgat atttatgaag ctttgatttt gggaacaaag actttggtat
    19561 taaatcatgg agttgttcaa cagtatgata ctcctgagaa tattttaaat actcctgcta
    19621 accaatttgt agaccagtta ttgaatataa gaaaatctat aatagatgat gataatttaa
    19681 aagaataaat ttaaatttaa aatcaaattg ttgtgataaa aactattgat ttagagctaa
    19741 cttcaagttg tatacttgaa gtggaaaagt tagattaagg tatagaaggg catttagcag
    19801 ttggctgtag acgaggtaac tgctgaaggt gctttcaata aatggctaga acctgtatct
    19861 gttgaagatt ataataaatt gaaataagaa gctcaatata cagagtagat aggcacttca
    19921 aatagaagtg tcttttgtgt gccataaaat aaatcaaaat attagcaaag aatgtgaaaa
    19981 acaaaataaa ataatatgct atctttaaaa taggagggat gctatatgga taacaatttg
    20041 attaccattg aaaaaacttt agattatata gaaaaacatc ttttagatga gatgttagat
    20101 ttaaatgtaa tttctaaaga gataggctat tcaaaatacc atttacatag aatgtttaca
    20161 tcagttgtcg gatttagtgt acataattat atacaaagac gtagacttac tgaagcagcg
    20221 agaatgctaa tttttacaga aaaaccaatt attgagattg ctttaatctc ggggtatgat
    20281 acacaacgct ctttttcaag agggtttaaa aaaatgttta aacgtagtcc taattttttt
    20341 agaagacatc aagatttttt accactacaa ttaaaatttg atattcataa tagaaaaaaa
    20401 ttacgtggag atatggtttt agatgttaaa aaagttaatt gtgcagatat aaatattgtt
    20461 ggctattctg gtaaagtaag aaaaggattt catattattg gaaaatgctg gagggatttg
    20521 cataaaaata aagagatgat agaaaataag gtagatttag gttttttaat tggagttagt
    20581 gattatagca attttaaaga gattgagaat actcctacat ttacatacat tgcaggtgct
    20641 caagtagcta cttttggcaa attacctaat ggaatggaaa aattcgtatt accgaaaagt
    20701 aattatattg tttttacttt tattgggaaa aatgaggata gtatgcaaaa tgttgtagaa
    20761 tatatctatc aagaatggtt ccctaattca agttgccagt ttaatgaaaa taatttatat
    20821 gactttgtaa aatatggaga aaaaactgat gagaatggtt tgagtgaaat tcagttttgg
    20881 gttccaatca tttaaaagaa ggtattatgt ataaagtaga tggatttata taggcaaagt
    20941 tttacagcag tatgtattta taaataattt atagtttgta ggaaagaaat aattttacta
    21001 taagattatg ataaaataca caatactatg acaaaatagt gttaaataat agatttaatt
    21061 ttgcatagga aaagttctat aatggtgtgt attcataaat aatttataat ctgtaggaaa
    21121 gaaatagttt tactataaga ttatgataaa atacacaata ctatgataaa atagtactaa
    21181 ataatagatt taattttgca aaggataagg tgttttaata aaaatgaatg tagaaaacga
    21241 attacttaaa aacctagata gattgcatac aacagagtta ggcgttgtaa gaattaagaa
    21301 aaatctttct ttggagacaa atgatgtagt gaactggtgt aaaactaaaa tagaatctcc
    21361 aaatgccatt attaatagaa agggaaaaaa ctggtatata agtgtatatg attgtattat
    21421 aacagtaaac gctcacagtt atacaattat tacagctcat aaagaaaaga aatgaattgc
    21481 aaaatacaaa ggtcaaaagc attttccact gtttgtagta cctatgaaga agtatataaa
    21541 ataatattac ttttgaataa taatttaaat tttggaggtt gaaaaaatga atgatactgt
    21601 aaaagaaaaa ttggcagagt cactaacttc tgatactact gatattttac cttatttgcc
    21661 ttatttatta caagattttt gggaattagg aagttcacca gaacaaatgt tacaattatt
    21721 tagaaagcat atacctttta atgaggatac aaaagttttg gatttagctt gtggaaaagg
    21781 tgctgtatct gtgaagcttg caaaagagtt gaatatacat atcaaaggta ttgatttgat
    21841 acctgaattt attgattatg ctagaagaaa ggctattgaa tataaggttg atgctttgtg
    21901 tgattttgaa atgaatgatg ctaatagttc tgtaaaaatt gagcatgatt atgattgtgt
    21961 gatttttgga gctgtagggg atattttagg taattataaa gaaactataa gtaagctatt
    22021 acctacaata aaaagtaagg ggttcatttt aattgatgat gcatatgtag tagataaatc
    22081 tacaaatgaa cagcttaatt ttgagagggt gtatcccact tacaatgagt ggtgtatatt
    22141 gttcaaagaa ttaggtctga agctaattga atgtatacca tgtttagaac ttgaaaatga
    22201 tgttgaagag gaaatgaatt ggattataac tcgtgcaaat gagctaatta aaaaatatcc
    22261 ttctcaaaaa gatatgtttg aacaatatgt tattagccaa aaaaatgaat atactgattt
    22321 acagcaggac cttgttggag caacttggat tttacaaaaa gaataagata aatattagac
    22381 tagataatca atgttatagt gaattatccc atgtctagtg aatataaata acataaaaaa
    22441 ccgtcaagat gaatagttta ttcgtgcttg acggttttta gtatttgttg aagtaaaatt
    22501 ttatttcttt agtatatcac ttttagtcaa tccatttgat ttagcttgag tattccattg
    22561 atgattcccc ataagtttat ataggaatct agggaagtta ggtgaaataa aaatagtact
    22621 tttgttggaa tcatctatat gtatattatc actaagtata ttttttgaaa gttcttttaa
    22681 tgcaattcct aaatcttttt taggtccttt acccaaaggt acggattcta gtgaaccaaa
    22741 catctcccca gctccaattc caataccttg aacccatgta aagttgattt ttttacacca
    22801 atgctctatc atttgaattg ccaaatgatt atgttcacct tcattgaatc cacagttaac
    22861 tattgcatac actggaatag gttttttatt ttgtgttttt aaaaattttt cacatttctc
    22921 taaaaaatga agtaaatgag atggaatacc atctacataa agaggagatg cgattattaa
    22981 tctatcacaa ttaagtatgg cattaagagc gtcaggatac ttagatgtgt tatctacttt
    23041 aaatgtaaaa actttattat cattttgaat aagttgtttt aattcagata aaaaatactg
    23101 tgaattattt ttatttactt ttggactacc atttatcatt actatattca tatggattca
    23161 cctcttatat cttgtatatt ttcatagaaa caaacagagt gttcttttat attgaaattt
    23221 atagcatttc catttactaa tttcgtagca gtttcttttt cagcttctgt aatacaatct
    23281 ccatagaata tagcttttaa atttatctgt ttatcatatc tgcttttatg acgcatcata
    23341 ttatctttta ttacaaagta tggaagaata taattaatgc ttttatcaag tacgtttttg
    23401 acaaaagggc taaaccctcc gtaacagcat ctgcttatta taataattcc atcagagtca
    23461 tttataagtt tacccatgtt gctgtaataa tcttttacaa cacattcaga aggagtttta
    23521 atccagcaac caaaacaacc aatacatttg tggatttctt ttgtgtttgg aagtattttt
    23581 atattgtcat caagtttggg taataacttt tctaattctt tgtcagttaa atcatgtatt
    23641 aaaagcctca taaagtccat ctccttttat tatgtatgtt tacttctaaa aattatatct
    23701 tatagatttt tcagtaaatc tttacaccaa ttaataacaa aattataata gtcaactcca
    23761 taaatcattg ttgcatacat atatgtatat tggtcaacac aatgattttc ttctgcatca
    23821 tttttttgtt tacttaattt atttagaagt aattctactt cagttattaa catttttaag
    23881 tttgtttcaa ttatttcttt gggtagatac ttgtaaaaga atatattaac aaggtggtct
    23941 tgctttgttt tagaaaaatt tataggtttc tttaaccatt caagaaatac ttctttacca
    24001 gtattagtta tggaatatag tttttttaat ttgttaccat ctataacttc gtgatagtgt
    24061 atatatcctt ttgtttctaa tcttttaagt gcaggataga tacttccaaa gctggcgtca
    24121 aaaaagtacg aggtactttc tgacattatt tgttttaagt cgtatccact taattctttt
    24181 tccattaaaa atcctaaaat aatgtattct aacatattac ctcctggtat caattagata
    24241 tatatcgatt cgatatattt attattacag ataataaatc ttacgtcaag atgcttttta
    24301 agataagcta aaaagaatta ggagttattg ataaatatgc aaaaaaatta atataaaagg
    24361 taattaaata tcaataaaga tttaaaaata gttaaatcaa agtaagagtc taatatataa
    24421 aatttatagt aactttatgg tttaaatata aacttgtgtg ctattgacaa agtataaaat
    24481 tagcagtaga ataattgcat gagcaaatag attgttgcga acgcaaaaaa aggacaatag
    24541 atattaaagg agagaatatg agagagctat taaaatgggt ttccattata aatagataca
    24601 atacaaatta tattgacagg aaattggcgg atattggaat caataatagc caatattttt
    24661 atgtattaca catatgtaat aatccaggta ttacacagga cactatattt gagaaaattc
    24721 ttgtgaatcc tagtaatata acaagagctt tggcaaattt agaaaaagaa ggctttataa
    24781 caagagaacc aggtgtaaag gataaaagaa catggcattt atatcctaca gaaaaatctt
    24841 taggatgtta tgatgaaata ctaaaaataa caaatgggta tgttgaggag ttgttgagtt
    24901 catttgagaa agaagagcaa gagttgttta tgtcaatgtt aaagaaagtt gcatttttgg
    24961 ctattgatat gaatgaagaa gcaaaattgg aggcgaagga aaatggaaga aaaatataag
    25021 gagccattgg aatatgaaaa ggtttcaaag ttattaacta agtacgcaat tcctagtatt
    25081 atagcaatgt tagtaagtgc tttatataac attgttgacc aaatatttat tgggcaaggt
    25141 gttggtgtat tgggcaatgc tgctacaaat gtcacttttc cactaacaac aatatgtact
    25201 gcaattgcat tattgttagg aattggagga gcgtctaagt gttcattgga attaggtgct
    25261 aaaaattcag aaaaagctac aaaagcagca ggaaattcta tatgcttgat ggctgttttt
    25321 ggaataagtt tatttatagt agtatcaata tttttaacac cactattaaa attctttggc
    25381 tctacatcag aaatactacc ttatgcacac acatatacaa aaattacatc aattggatta
    25441 ccatttctta taatgtccac tggaatgagt aagttgatac ttgcagatgg gagaccgaaa
    25501 gcttctatgt tttgtatgtt aataggagca gttattaata caattttgaa tccattattc
    25561 atttttgttt ttaatatggg aattgctggg tctgctttag caactgttat tgggcaactt
    25621 atatcttttg gaataagtgt tcattatata aagaattttc aacatattaa attacataag
    25681 aaaagtttta aattagatag tataatttat aaacatatat ttgcgctagg ttcaagctca
    25741 tgttttaatc aattagcaat gactgtaaca cagatagtta tgaataatac attggcatat
    25801 tatggggcta ggtcagttta tggaagtgag attccacttg cttgtgtcgg tatcattatt
    25861 aaagtaaata tgatttttat atctataatt attggtatat cacaaggtat gcaaccaatt
    25921 atagggtata attatggggc tgaaaagtat aattgtgtaa aagaagcata taagtttgca
    25981 gtgggaagtg caactattat atctgttatt gcattcttat gtttccaatt attcccaaga
    26041 caaattacgt ctatatttgg taacggaaat gagacttatt ttatatttgc agaacattat
    26101 tttagaactt tcttgttctt aacatttata aatggtgttc aaatagtatc atcaactttc
    26161 tttacatcaa ttgggaaatc agtgttggga ctttttactt ctttgactcg tcaaatttta
    26221 tttttaattc cattgatagt aattttacca atgtttatgg gaattgatgg agtaatgttt
    26281 gcaggaccaa tagcagatgc agcagcggca atggtatgta tatactttgc agttcatgaa
    26341 atgaaatcat tgactataaa gcaaaataat ttgatgagta accataataa gattgcagag
    26401 gtataagaca atatttaaga agtatagaaa attaatttaa agaagtataa taaactaatt
    26461 taggaagtat agaaaattaa tctaaagaag tataataaac taatttagaa agtatagaaa
    26521 attaatctaa agaagtgtaa taaactaatt taggaagtat agaaaattaa tctaaagaag
    26581 tgtaataaac taatttagga agtatagaaa attaatttaa agaagtataa taaactaatt
    26641 taggaagtat agaaaattaa tttaaagaag tataataaac taattcagga agtatagaaa
    26701 gctaatctaa agaagtatag taaactaatt taggaagtat agaaaattaa tctaaagaag
    26761 tataataaac taatttaaga aatatagaaa attaatttaa agaaatacaa tacattaatt
    26821 tttaagtaac attaaattaa tgtaagtaaa ataatgttca tatgaagatt taaaggtgca
    26881 ttttctgaag ctaagtatat gttgtagagt gttaggtctc tctatcctgt gaagtttaat
    26941 agctcaagaa aatgcactat ttatgatgat tattttgttt tatttccaat tttggaaata
    27001 actattctaa ttaaatctaa aattatacca taaataagaa aagaaagtat agatgctatg
    27061 taccaataaa tcgaaattga ccctgtaatt gttctacatg ggatttgcat acctgaatcc
    27121 ataaaaacaa aaaaactatc aactctggaa ataatagaca aaataggatt taaacctatt
    27181 agaacaatac tttttgagtc ttgaccaatt tgatgcatat aaatctcaaa taatgcaatt
    27241 aaaaaaaacc aaaatgtaaa agatttaata atttttttca tcaaaatacc tcacataata
    27301 taaattctgt ttgcactatt tgcttactac aactatttat ctccattcag tcacatcact
    27361 taattgtaat ctaggtcttc ttgatggttc ttcatcagga taacccaaag atattgctgc
    27421 cactaattga ctatctgtat ttaaccattc acataattca cgatatgcaa agtatacatc
    27481 acaaatccaa agactaccta gacctaattc cacagctgta agcgacatat tctgaattgc
    27541 agctccaatt gattgcatgt ttgccatttc atagaatcgt tcttcagggg atagcttttc
    27601 taaaggtgat ttacctaata tatttaaaat aaaaattgtt actggagctt gtttcatgat
    27661 ttcaactgtg taatttgcac cagcgatatg ttgacgactt cctggaagaa gcccattatc
    27721 attaatttca ttttgaatac ctttgctcat ggctttaagc atagattctt tttccttttc
    27781 agtgatgaca acaaaacgcc atggttgcct gtttttagat gaaggtgcat ttattccagc
    27841 ttcaattatt ttctctatag tttcatgtga aatgctttga tttttatatt ttctgatact
    27901 tcgtcttttt gatatagaat cacttatcat tttaagtaac ctccgtttat tttttggaaa
    27961 aatctattta atttttattt tctattttaa ttattttagc attaatcaga aaaaaagtca
    28021 ttgattttag tatacaatta ttaatgatta tattaagaat tgtatcaaaa agtatgtgat
    28081 tatactaagg gattatatta aacattatat ttaaaattgt atgaaaggtt gtatttaata
    28141 ttatattgag agatatatat attaggattt atatatattc agatttatta ttatattgag
    28201 ccttatatta aattaaggac tataatttga aaataagcta taaaaactta atattgtttt
    28261 gttcagagat aaaaaaagaa tactttaggt gatttttatt aaaaattaag agtgataaaa
    28321 ttatatactt tataaatgta aatatgacga ataaaaatga taaatataat aatatatata
    28381 tttacattag gagttttcta tactataatt atttaaa
//
LOCUS       DAEPHU010000056        27845 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 01A10CD0081
            SAMN05941466-rid12468953.denovo.056, whole genome shotgun sequence.
ACCESSION   DAEPHU010000056 DAEPHU010000000
VERSION     DAEPHU010000056.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941466
            Sequence Read Archive: SRR6291087
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 27845)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 27845)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068158.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 22:43:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,892
            CDSs (total)                      :: 3,805
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 87
            rRNAs                             :: 8, 1, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 55
            CDSs (without protein)            :: 55
            Pseudo Genes (ambiguous residues) :: 0 of 55
            Pseudo Genes (frameshifted)       :: 21 of 55
            Pseudo Genes (incomplete)         :: 28 of 55
            Pseudo Genes (internal stop)      :: 16 of 55
            Pseudo Genes (multiple problems)  :: 8 of 55
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..27845
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941466-rid12468953.denovo.056"
                     /strain="01A10CD0081"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            complement(<1..199)
                     /locus_tag="KR231_002511"
     CDS             complement(<1..199)
                     /locus_tag="KR231_002511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HBH0004875.1"
                     /translation="MNREKLVAFIRYLSLFILVVSYLKNVENTLYPVITMIILFLIII
                     NNQVRFFSLSNENKFILISYFL"
     gene            383..727
                     /locus_tag="KR231_002512"
     CDS             383..727
                     /locus_tag="KR231_002512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YraN family protein"
                     /protein_id="HBH0004876.1"
                     /translation="MNNKEKGDFGEKVAVNYLLSKGAKILEKNYRLKIGEIDIIAKME
                     DEIIFVEVKSRSNIKFGYPCESVSFKKRKKIIGVANYYIIKNNLNNTPVRFDVIEVYL
                     LEKRINHIMNAF"
     gene            758..2359
                     /locus_tag="KR231_002513"
     CDS             758..2359
                     /locus_tag="KR231_002513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YifB family Mg chelatase-like AAA ATPase"
                     /protein_id="HBH0004877.1"
                     /translation="MLSIINSSNLVGIDSFLVKVEVDVSNGIPSFNIVGLPGKEIKEA
                     RERVKSAILNSGYKFPSTRIVVNLSPADIKKEGAFLDLSISIGLLRELIKKDENYIRE
                     SMFIGELSLDGKIRKVRGILPIIMGAKTQNIKRIFIPIENIKESLFVDEIDIIPIKSL
                     KECVDFLNEEIKVDKVRIMSFLDDKSRKENEELEKDNSYIDCKYTKINNEESKYDEDF
                     KDVKGNYFVKRSAEIAAAGNHNMFMIGPPGSGKTMIAKRVRTILPDISVEEMIEVSKV
                     YSILGMINETKGIIDKRPFRAPHHTTTKQSLIGGGMDARPGEIALAHRGILFLDEIAE
                     FDRKILETLRQPIEDGYVNISRVKYSAKYPCRVLLVAAMNPCPCGYYMSETECRCRSN
                     EIDRYINKISGPLLDRFDIFVEVNSIKYSDFNSLKQEESSQKIKRRVENARKIQINRF
                     KKDNIKNNSEIKAYNLFKYCKLEKEASKTAEMIFNKYNLSSRSYTKLLKMARTIADLE
                     ERDLINSQCIIEAFSFRKAYYSYFK"
     gene            2378..3478
                     /gene="dprA"
                     /locus_tag="KR231_002514"
     CDS             2378..3478
                     /gene="dprA"
                     /locus_tag="KR231_002514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-protecting protein DprA"
                     /protein_id="HBH0004878.1"
                     /translation="MEKRDTYLWLKSIGGITTKTIEIIENEIVNIEDIFDFSEKEIYN
                     LKNISLNIRKNIVKYRGHAYLENIKELLYKKAIKYICKYDKEYPENLKNIYNAPKLLF
                     YKGDIGLVNNNFNIAIVGSRKPTAYGINCAKTISCQLSQYGVNIVSGLAIGIDAYSHI
                     GCMSGKSKTIAVLGSGVDNPLPKQNLHLSNKILENGGLLLSEYNINSTVAPYHFSNRN
                     RIISGLSDGVVVVEAAIKSGALITVDFALEHGKNVFAIPGNINSQMSRGCHKIIKEGA
                     KLIENIDDILNEYNIFNIIDKKINQKYDNISLNAKSKQIIEAIKREGNLHIDSICDYT
                     GIEIKYVNSIINELVLNELVVEMNNKTYSLNV"
     gene            3511..5598
                     /gene="topA"
                     /locus_tag="KR231_002515"
     CDS             3511..5598
                     /gene="topA"
                     /locus_tag="KR231_002515"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I DNA topoisomerase"
                     /protein_id="HBH0004879.1"
                     /translation="MAKTLVIVESPAKAKTIEKFLGKSHYTVKASVGHVRDLPKSKLG
                     VDIENNFEPQYINIRGKGDVIKELKKEAKKSKQVYLATDPDREGEAISWHLAHILNLD
                     ESEDCRIEFNEITKDAIKKAIKHPRNIDINLVDAQQARRVLDRLLGYQISPILWQKVR
                     KGLSAGRVQSVTTKLICDREKEIKAFIPKEYWTIDVEAKTVKDKDITLKFYGKNDEKI
                     ELENEEAVNEILKEMEGKDLKVEKIESKSRRKSAPKPFTTSMLQQEGANKLFFTTKKT
                     MMIAQELYEGIDIEGEGTVGLISYIRTDSKRISDEAKEKAKGYIVNNLGENYYKNTGD
                     KKEKKDTKKVQDAHEAIRPTSVDRTPESIKASLSKDQYKLYNLIWRRFVASQMEDSVF
                     DILNVECKIGDIVFKATGSKMKFDGYTKVYNFSEREDKILPSIEKGDILNIENILPDQ
                     HFTQPPARYTEASLVKTLEELGIGRPSTYAPTIATILNREYVEKQGTSLCPTELGIIV
                     TDILENNFHKFIDVDFTADMESKLDVIEEGNTDWKKIVSESYAPLKEAIEEALENIEK
                     VNMDEETDEICENCGSNMVIKYGRFGKFMACKNYPDCKTTRPIMNKIGVKCPKCEEGD
                     IILRKSKRGKAFYGCSNYPNCDFVAWNKPTGEFCEKCGSYMVEKVTKSETKTVCSNKE
                     CNKETKEHNDGKE"
     gene            5763..6548
                     /gene="codY"
                     /locus_tag="KR231_002516"
     CDS             5763..6548
                     /gene="codY"
                     /locus_tag="KR231_002516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-sensing pleiotropic transcriptional
                     regulator CodY"
                     /protein_id="HBH0004880.1"
                     /translation="MASEVLQKTRKINKTLQTSGGSSVSFDLLAGALGDVLSSNVYVV
                     SAKGKVLGLHLNDVQDSSVIEDEYTKQKKFSDEYTQNVLKIDETLENLNGEKILEIFP
                     EEHGRLQKYTTVVPILGSGQRLGTLVLSRYSNSFNDDDLVIAEYSATVVGLEILRAIG
                     EELEEEMRKKAVVQMAIGTLSYSELEAVEHIFAELDGKEGLLVASKIADRVGITRSVI
                     VNALRKFESAGVIESRSLGMKGTHIRILNDKLTDELKKLKNNQ"
     gene            6655..7920
                     /locus_tag="KR231_002517"
     CDS             6655..7920
                     /locus_tag="KR231_002517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication-associated recombination protein A"
                     /protein_id="HBH0004881.1"
                     /translation="MPLADKIRPKTMNDVIGQSHIIGNGKILSKILQSNFLPNMIFFG
                     PPGVGKTTVAEIIAERSNKSFYKINATNSSLEDIKKVISELGSINNVNGVLLYIDEIQ
                     SFNKKQQQSILEFMENGSITLIASTTENPYHYVYKALLSRSTVFEFKPLEKLDVEKGL
                     KRAVEVLNEDSYMDIECNNNAIEDIAILSDGDMRRALNILEVVVYSTKPNKDNITYID
                     SDVIRASTFNKIINYDKNGDSHYDILSAFQKSIRGSDPQASIHYLARLIKGGDLISIC
                     RRLLVIASEDIGLAYPNAIVIVKACVDSAMQLGFPEAKIPLAEATILLATSPKSNSAC
                     IAIMKAMDELDKEFVKDIPNSIKDSHYSGSKEIGRGCGYKYPHNFKNHYVKQQYLPDS
                     IKDSIYYIPQENKTEKNIKKYLEYLNSDF"
     gene            7951..8721
                     /locus_tag="KR231_002518"
     CDS             7951..8721
                     /locus_tag="KR231_002518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBH0004882.1"
                     /translation="MIIKLNSTYHSRVMKYLKKEPEYNLFIIGDIERYGYGNNFLNIW
                     ADVGEHGEIKAILLKYFEFMIFYSDGEYDVEGFYNLLRNTNYEEISGKICAVDALAKR
                     LGLNNLKVVDFCKLQTKKFLIDNNCNAKVKRIRLGNLKKTVKLYDLIDEFHSTTLENL
                     KNGLRTGRGYCIEINKQVVSMAKSTSENRTHAMIIGVGTHPKYRAKGLATKCLIKLCS
                     ELLRENKIPCLFYDNEEAGKIYKKLGFENIGKWGIYSK"
     gene            8830..9276
                     /locus_tag="KR231_002519"
     CDS             8830..9276
                     /locus_tag="KR231_002519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rrf2 family transcriptional regulator"
                     /protein_id="HBH0004883.1"
                     /translation="MKLSTKGRYGLKAMFELALNQDNGPVSLKFIAKKQKISDQYLEQ
                     IFSSLKKSGLVKSVRGAQGGYLLSKNAEDITVGDILVVLEGPVALSDCVLDEDVCENS
                     NMCVTKIVWEKMKKGIEDVIDSITLKDMINDYNKNKLENDITNIKK"
     gene            9294..10487
                     /gene="nifS"
                     /locus_tag="KR231_002520"
     CDS             9294..10487
                     /gene="nifS"
                     /locus_tag="KR231_002520"
                     /EC_number="2.8.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase NifS"
                     /protein_id="HBH0004884.1"
                     /translation="MEKRRLYMDYSATTPIKKEVLDAMMPYLTDYFGNASSFHTFGRE
                     AKDALDKAREQVAALINAEPSEIYFTAGGSESDNWTLEGVAYANKNKGNHIITSKIEH
                     HAILHTCEYLAKHHGFEITYLDVDSEGKVDLKQLEDSIKDTTILISIMFANNEIGTIQ
                     PIKEISEIAKKHKILFHTDAVQATGNIPVDVKELGIDLMSMSSHKIYGPKGVGALYIR
                     KGVRLHNFVHGGAQEKSKRAGTENIPAIVGYGKAAELAKENMQNHVETLTRLRNKLID
                     GVLERIPYTRVNGSLDNRLPGNANFAFQFIEGEGILLLLDMLGIAGSSGSACTSGSLD
                     PSHVLLAIGLPHEIAHGSLRLTVGDFTTDDDIDYILENLPKVIERLRSMSPLYDDAKK
                     QGLVK"
     gene            10541..10981
                     /gene="nifU"
                     /locus_tag="KR231_002521"
     CDS             10541..10981
                     /gene="nifU"
                     /locus_tag="KR231_002521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly scaffold protein NifU"
                     /protein_id="HBH0004885.1"
                     /translation="MQYSDKVMEHFMNPRNMGEIDNASGVGEVGNPTCGDIMKIFLDI
                     DGDVIKDVKFKTFGCGSAIASSSMATEMIKGKTIKDALELTNKAVAEALDGLPPVKMH
                     CSVLAEQAVKAALIDYAQKNNIHIPELDGYVIDDAHDHDVEEEE"
     gene            11270..12349
                     /gene="mnmA"
                     /locus_tag="KR231_002522"
     CDS             11270..12349
                     /gene="mnmA"
                     /locus_tag="KR231_002522"
                     /EC_number="2.8.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 2-thiouridine(34) synthase MnmA"
                     /protein_id="HBH0004886.1"
                     /translation="MNKKVMIGMSGGVDSSVAAYLLKQQGYDVIGVTMKLWQDDDVVE
                     IEGGCCSLSAVEDARRVANKIGIPFYVLNFREVFKEKVIDYFIDEYLEGKTPNPCIAC
                     NKHIKFDDFYKKARQIGCDYVATGHYAKIEKDESTGRYLLKKSVTDKKDQTYALYNLT
                     QEQLEHTLLPIGDYEKDRVREIAKEMGMAVHNKPDSQEICFVKDNDYANYVKKHSKKR
                     IEEGFFVDTKGNILGKHKGILYYTIGQRKGLGITFGKPMFVIDINPINNTIVLGDNED
                     LFKKELIAKDVNFISIDTLEEPLRVQAKIRYSAKPSPATIHRVGEDTIKIVFDEAQRA
                     ITKGQSVVMYDGDIVVGGGIIEKSL"
     misc_binding    12492..12730
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            12798..15437
                     /gene="alaS"
                     /locus_tag="KR231_002523"
     CDS             12798..15437
                     /gene="alaS"
                     /locus_tag="KR231_002523"
                     /EC_number="6.1.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428286.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine--tRNA ligase"
                     /protein_id="HBH0004887.1"
                     /translation="MEKMGLNEIRSKFLEFFESKGHYVANSYSLVPNNDKSLLLINSG
                     MAPLKNYFSGVEVPPSVRMCTSQKCIRTGDIENVGITARHATFFEMMGNFSFGDYFKR
                     ESIKWGWEFVTEWLNIPEDKIWVTVYEEDDDSYDIWAKEMNFPEERMVRLGKDDNFWE
                     IGTGPCGPCSEIYFDRGEEYGCDNPDCKPGCDCDRYLEFWNHVFTQFDRDEEGNYSLL
                     ENKNIDTGMGLERMGCIMQGVDTIFEVDTIKSILEAVEKLTGVKYGENPKNDISIRII
                     TDHIRAVTFLVSDGVLPSNEGRGYVLRRLLRRAARHGKLLGVKELFLQKLIDEVIKVN
                     DKAYPVLVEKESYIKKVVGIEEEKFNETIDQGTEILNSYIEVLKNEGKTVLSGQEAFK
                     LYDTYGFPIDLTKEILEEEHLSVDEEAFNEEMEKQKERARNARGNMDGESWKEDPLSK
                     LESTVDSTFNGYSEIYGEGTIEAIVKDDELVQSAEEGDKVSIVLDNTTFYPEGGGQVG
                     DCGLITNENLVLEVLNTKKGANNSIKHIGIIKSGRISNGDKVKTLVDRETRMSAARNH
                     SATHLLHKALREVLGEHVNQAGSLVTPERLRFDITHFEAISNEELKVIEEKVNNVILS
                     SLDIKCDIMNIKEAKEKGATALFGEKYGDEVRVVSMGDYSTELCGGTHLTNTSQVGMF
                     KILSEGGVAAGVRRIEAITGKAVYEYLKERDGIISEVCVNLKSKEDNLIQRISSLLEE
                     NKNLSKELHDMKAKMSLQSVDSIFDSKVEVNGVNLITNKFEGMDMDTLRETADNLRDK
                     LGSGVVVLANVVDDKVNFVVTATKDVLDKGIHSGNIVREVAKIAGGKGGGRPNMAQAG
                     ASDVSKVDQALSYASEVIKTQVK"
     gene            15462..15719
                     /locus_tag="KR231_002524"
     CDS             15462..15719
                     /locus_tag="KR231_002524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IreB family regulatory phosphoprotein"
                     /protein_id="HBH0004888.1"
                     /translation="MEKDLDYTMKFEGIPEDRMSVGDTIDFVYKALVEKGYNPINQII
                     GYLLSGDSSYITSHKNARAIIKKFERDEILEEVITHYLNRK"
     gene            15729..17900
                     /locus_tag="KR231_002525"
     CDS             15729..17900
                     /locus_tag="KR231_002525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0004889.1"
                     /translation="MRKKIMSLFAIVIMIFVSTASYGFAEEKGKVIFIDMNRTNLGSM
                     MNIPILKNEIEKRGYVALMNIRGDQGTDDRRSCASMGAGTRASVTTEDYINFQKVDQD
                     TAKAFEVATGQKAKEINDLGINRSINENLEYGEYGANLGSLGKTLSENGLKTSVIGNA
                     DIIENNQLVKNRNLCLVAMDQYGRIDSGNIDNINKKDSKMPFGISTDYDKLLDETKKS
                     YKNSDAIFVELGDTYRLDMYRLNLNDNTYDTMKKNIVKNINKYLEQVFSMVGENDTVY
                     IASAFPSDLDYKNKRRLSPIIKFSGEGKGLLESATTRKAGIVANLDVGVDILGTFGLE
                     NKEMVGRSYTLVNKEDNISYLKSLYERIVSISSIRSTIINGFVGVISASWVIAMFAIF
                     FRNYMPHKERVFKVLKEFIKLGIIMPLSFMLAPLMNFKTPISISLGIFATTLILYLLG
                     RKLFKDNDIKHMGFFATLTILVIVIDSVFGTYLMQNNIMSYDAVIGARYYGVGNEYEG
                     VTIASAVFGLAVLLHYKKVSKLLVVIFSLIILITSAYPSMGANVGGAISECVAYLLFI
                     MLIYDIKIDFKKAVLLAVSAVVVVFAFAALDILSGSESHLGMFVQRIFLNGPGEILQT
                     FGRKIQMNMQLAQTSVWVNILLVGIGVIAVLIFKPSRHFRKIMNNFPILFKGFIASMV
                     GCIITLLVNDSGIVAASTASIYILIPLIIISINMIIFEKNN"
     gene            18106..18531
                     /gene="ruvX"
                     /locus_tag="KR231_002526"
     CDS             18106..18531
                     /gene="ruvX"
                     /locus_tag="KR231_002526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428279.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RuvX"
                     /protein_id="HBH0004890.1"
                     /translation="MLDGRIMGLDVGDKTIGVAVSDLMGLTAQGVKTIKRVGKKKDIE
                     ELKAIIKEKQVNKIVSGLPKNMNGTLGPQGEKVIKFCELVKAETGIDVEFWDERLSTV
                     AAERSLLEADVSRQKRKKVIDMLAAVIILQGYLDFKINS"
     gene            18609..18896
                     /locus_tag="KR231_002527"
     CDS             18609..18896
                     /locus_tag="KR231_002527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1292 domain-containing protein"
                     /protein_id="HBH0004891.1"
                     /translation="MEENIINLIDENGVESQFEIILTLEAEGKEYAILMPLDDEEAEE
                     ALIFRIDEDEEGEILIPLESDEEYETVVAVYTAIMEEEGLNYDEDESNGLN"
     gene            19178..19636
                     /locus_tag="KR231_002528"
     CDS             19178..19636
                     /locus_tag="KR231_002528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor"
                     /protein_id="HBH0004892.1"
                     /translation="MANTMDLLKDKLKETGFKITPQRRAIVEILLKHDHSHLSSEEIY
                     DLVRVDCPEIGLATVYRTMQLLDEIGLISKLNLDDGCIRYEISLHKEDCHNHHHLICK
                     NCGKIMEAKEDLLDNIEKEIQSLYKFKILDHDVKFYGLCDECNGVSDSEE"
     gene            complement(19753..20490)
                     /locus_tag="KR231_002529"
     CDS             complement(19753..20490)
                     /locus_tag="KR231_002529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent hydrolase"
                     /protein_id="HBH0004893.1"
                     /translation="MRGKTHCAIGILTAIQTSLIFKIPISLVDILVSATFAVLPDLDK
                     SNSMVSNFILKNNVSKYIYRIFIYAVNIIIFFISININDNFYLSAIITFVAIIIIESK
                     LTHTFLRKVFLSLIFILLAICLYIIEVEIYFTIFCLMLSIFPWLKHRSFSHSIFATII
                     VYFLLKQIELITNINNLSFYGTIGYASHMFLGDLFTKQGIPIFYPLSEKKISLGFLTV
                     GGPFSNFIEKSFIFVLIGLIIFSILKL"
     gene            20707..22383
                     /locus_tag="KR231_002530"
     CDS             20707..22383
                     /locus_tag="KR231_002530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HBH0004894.1"
                     /translation="MQLFKKNTNKIKVMALGGLNEVGKNMTVVEYKDEIIVIDAGLSF
                     PEDEMLGVDIVIPDITYLVKNRDKIKGIFITHGHEDHIGALPYILKKINVPVYGARLS
                     IGLIQVKLKEHKMNNVKLNVIGPRQVIKLDNMEVEFLKNNHSIPDAYSIAIHTDQGII
                     YHTGDFKIDLTPIDGDVMDMHRICELSKKGVLLMLADSTNAEKPGFTMSEKTVGVGLD
                     ELFAKGNGRRIIVATFASNIHRLQQIINTAEKFNRKVAISGRSMVNVVGVAKELGYLD
                     ISDDMLIDLNDICKYEDSELVIITTGSQGEPMSALARMAFSEHKKVEIKSGDLVIISA
                     HPIPGNEKLISRVINFLFEKGAEVVYSDIADIHVSGHACQEELKLIHALVRPKFFMPA
                     HGEYRMLKRHAEIAEQLGMDKENIFVMQTGDVLELDKNSAKVANRIQTGNILVDGLGV
                     GDVGNIVLRDRKHLSEDGLMIVVVTISKDEGKVLAGPDIISRGFVYVRESEDLMDGAK
                     DIIKNVLNECEEKNIKEWAYLKNNIKENLKEYLYQKTKRNPMILPIIMEV"
     gene            22591..22791
                     /locus_tag="KR231_002531"
     CDS             22591..22791
                     /locus_tag="KR231_002531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="spore protein"
                     /protein_id="HBH0004895.1"
                     /translation="MDDVSRQNAIKALKQTKMEIAGEYGMNYEDAFEIIENASNKGVL
                     EGYFKKLEKKKNLGQGISRHLE"
     gene            22845..24008
                     /locus_tag="KR231_002532"
     CDS             22845..24008
                     /locus_tag="KR231_002532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase"
                     /protein_id="HBH0004896.1"
                     /translation="MKKLASTALAILIALTPLSFSFANNKENADANQLNISSKSAILM
                     DVGSGQILYEKDAHKKLPPASVTKVMTMLLIVEALDSGKIKLDDEVQVSETASSMGGS
                     QIFLEPGETQKVDTLLKGIAVASANDACVAMAEHLAGSVEGFVDRMNAKAKELNMNDT
                     HFANTNGLPVANHYTSAHDIALMSRELLKHEMISKYLTTWMDKVVVGKKQVTVGLANT
                     NKLIKHYQGATGVKTGFTQEAKYCLSASAKRGNTHLVAATLGAETSPERFNDASSLLT
                     YGFANYESVKLCSKGDNIATLTLDKADENKVKLVAKEDLNALIKKGSSKEFEKKIEIV
                     KNPKMPIKKGTVLGKIKICKDKKVIGEVELINTKDINKASYLQMLQRIIDNMI"
     gene            complement(24219..24641)
                     /locus_tag="KR231_002533"
     CDS             complement(24219..24641)
                     /locus_tag="KR231_002533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2000 domain-containing protein"
                     /protein_id="HBH0004897.1"
                     /translation="MENKNSKCVMVIDENLPMGIISNTAAIMGITLGKHAPETVGPDV
                     IDKTGNSHLGIIDIPVPILKGNKEIIKDLRKKLYTLEFNDLTVVDFSDVAQSCNLYEE
                     FTQKIASVPEDELQYFGIAIYGNKKKVNKLTGSMPLLR"
     gene            complement(24662..25498)
                     /locus_tag="KR231_002534"
     CDS             complement(24662..25498)
                     /locus_tag="KR231_002534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HBH0004898.1"
                     /translation="MRQEERTVCFDRELKIEAYRFKGIMQKFPNHFHEHYVIGFIEKG
                     QRYLSCKNKEYTTSTGDLLLFNPFDSHTCEQIDDKVLDYRCINIKPEIMKKTVFEITG
                     KNYLPKFNQPVIFRSELVPLLQELHYIIMEEELDFKKEELFFFLIEQLIEEHTEPNLQ
                     SNLENTNIEIQAVCDYLENNYAEHIILDELSTIAGMNKYSLLRNFTKLKGITPYRYLE
                     NIRVNKAKKLLEKGVEPIDAAIQTGFVDQSHFTNFFKNFIGLTPKQYQNIFINDDSNN
                     FK"
     gene            25796..26392
                     /locus_tag="KR231_002535"
     CDS             25796..26392
                     /locus_tag="KR231_002535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-2 protease family protein"
                     /protein_id="HBH0004899.1"
                     /translation="MLSMNIGEIVASLVGIAMAISIHEFGHAYSAHLLGDDTAKAYGR
                     MTLNPVRHVDPIGLLAMFILKIGWAKPVPVNPNNFKNYKIGNLIVSLAGVFCNVLTAI
                     LCVIINKYVHMYAINTIAEYVFLYSIGFAAFNLLPIPPLDGWGVISTFVPYKWNEYLY
                     KFESMSYIILLIALFTGMYRIILTPIYAVLLKIVYLFV"
     gene            26422..27141
                     /locus_tag="KR231_002536"
     CDS             26422..27141
                     /locus_tag="KR231_002536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="segregation/condensation protein A"
                     /protein_id="HBH0004900.1"
                     /translation="MKYNIQLQVYEGPLDLLYDLITKHKIDIKDISIIDITKQYLNYL
                     KMLDKMDLEITSEFITMASKLLEIKSKYLLYKQKDEEEDPRIELMEKLEEYRKFKVAS
                     QDIKENITYVNERFYRNKEEIIIDDNVDLEDISIEAIKNILPYIFKVKTSQIENANDE
                     KLDKIVRKKIISVEEKILYIRDIIKEKIEVTFTNIIKSYENDEIIATFLSILELIKEK
                     EIVVVQDIFFDDILIRKSSEC"
     gene            27143..27682
                     /gene="scpB"
                     /locus_tag="KR231_002537"
     CDS             27143..27682
                     /gene="scpB"
                     /locus_tag="KR231_002537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SMC-Scp complex subunit ScpB"
                     /protein_id="HBH0004901.1"
                     /translation="MKREDIKYIIESVMFAYGEPISIKELNYIINKELSSKEIEIMLN
                     LLIEEYREQNRGIQIIKLENKYQMCTNKDYAEYIKKIIEPKKKKSLSQATLETLTIIA
                     YKQPITKVEIEDIRGVKCDKVLQTLFENELIREAGRLNKIGKPIIYKTTDEFLKLLNI
                     ESLEELPPIENYQEVATNE"
BASE COUNT        11291 a         2908 c         5007 g         8639 t
ORIGIN      
        1 ctaaaaagta agaaataagt ataaatttat tctcatttga taaagaaaaa aatctaactt
       61 gattatttat tataattaga aataatatta tcatagttat gaccggatac aatgtatttt
      121 caacattttt caaatagctt acaactaata taaataaaga taaatatcgt ataaaagcaa
      181 ctaatttttc tctgttcatt aaaggcactc ctccaaaaaa ataaactttt actatgaaaa
      241 ctagaataat atcataaaag aataaagtca ataaaagtat ttattaatat tgatggaaat
      301 aaaatcaatc caaaaacttg aatagtaaaa ttgtatactg acaataattt aaaagtgaaa
      361 atttaatgta ttggagtgaa taatgaataa taaagaaaaa ggtgattttg gagaaaaagt
      421 agcagttaat tatttgctat caaaaggagc aaagatacta gaaaaaaatt acagattaaa
      481 gataggggaa atagatataa tagcaaaaat ggaagatgaa attatatttg tggaggtgaa
      541 atcaaggtct aacataaagt ttggctaccc ttgtgaatct gtaagcttca aaaaaagaaa
      601 aaagataatt ggagttgcaa attattatat tataaaaaat aacttaaata acactcccgt
      661 aagatttgat gttatagagg tatatttatt agaaaaaaga ataaatcaca taatgaatgc
      721 tttttaaaaa agataatgtt tttggaaagg attaaatatg ttaagtatta ttaattcaag
      781 caacttagta ggaatcgaca gctttttagt taaggttgaa gtagatgtaa gcaatggaat
      841 acctagtttt aatattgttg gtcttccagg caaagaaatt aaagaagcaa gagaaagagt
      901 aaagtcagca attcttaata gtggatataa atttccaagc acgagaatag ttgtaaattt
      961 atcaccagca gatataaaaa aagaaggagc ttttttagat ttatctataa gtataggcct
     1021 tttaagagag ttaataaaaa aagatgaaaa ttacataaga gaaagtatgt ttataggaga
     1081 attatcatta gatgggaaaa taagaaaagt aagaggtata ttgcccataa ttatgggtgc
     1141 aaaaactcag aacataaaac gtatttttat accaattgag aacataaaag aaagtctatt
     1201 tgtagatgaa attgatataa ttcctattaa aagtttaaaa gaatgtgtcg attttttaaa
     1261 cgaagagata aaagtcgata aagtaaggat aatgtctttt ttggatgata agtcaagaaa
     1321 agagaacgaa gaattagaaa aagataatag ttatatagat tgcaaatata ctaagattaa
     1381 taatgaagaa agtaaatatg atgaagactt taaagatgta aaaggaaatt attttgtaaa
     1441 gaggagtgca gaaattgctg ctgctggaaa tcataatatg tttatgattg gacctccagg
     1501 ctcaggaaaa actatgattg caaaaagagt aaggacaatt ttaccagata taagtgtaga
     1561 agaaatgata gaagtaagta aggtctatag tatattgggt atgataaatg aaactaaagg
     1621 aataattgat aaaagacctt ttagagcacc tcatcataca actacaaagc aatctttaat
     1681 tggaggagga atggatgcaa gacctggaga aattgcttta gcacatagag gtatcttatt
     1741 tttagatgag atagccgaat ttgatagaaa aatacttgag actttaagac aacctataga
     1801 agatggatat gtaaatatat ccagagtaaa gtacagtgca aaatatcctt gtagagtact
     1861 gttagttgca gctatgaatc catgtccatg tggttattat atgtcagaga cagagtgtag
     1921 atgtagaagt aacgaaattg atagatacat aaataaaata tcaggtccat tgttagatag
     1981 gtttgatatt tttgtagaag ttaattctat aaaatattca gattttaatt ctttaaaaca
     2041 agaagaaagc tctcaaaaaa taaagagaag agtagaaaat gctagaaaaa tacagataaa
     2101 tagatttaag aaggataata taaaaaataa tagtgaaatt aaagcttaca atttatttaa
     2161 atattgtaaa ctggaaaaag aagcttcaaa aacggctgag atgatattta ataaatacaa
     2221 cctaagcagt agaagttata caaaactttt aaaaatggca agaacaatag cagatttaga
     2281 agaaagagac ttgataaatt cacagtgtat tatagaagct ttttcattta gaaaggctta
     2341 ttatagttat tttaaatagt tttttgaggt ggattttatg gaaaaaagag atacttattt
     2401 atggttaaaa tcaattggtg gaataacaac aaaaacaatt gaaataatag aaaatgaaat
     2461 agtaaatatt gaagatatat ttgatttttc tgaaaaagaa atatataatt taaaaaatat
     2521 aagcttgaat attagaaaaa atatagtaaa atatagaggt cacgcttatt tagaaaatat
     2581 aaaagaacta ctttacaaaa aagcgattaa atatatttgt aaatatgata aagaatatcc
     2641 tgaaaattta aagaatatat acaacgctcc aaagttatta ttctacaaag gtgacatagg
     2701 cttagttaat aataatttta atatagctat agtaggttca agaaaaccta cagcctatgg
     2761 aattaattgt gcaaaaacaa taagttgtca actatcccaa tatggagtta atatagtaag
     2821 tggattagct ataggaatag atgcatactc gcacataggt tgtatgagtg gaaaatctaa
     2881 aactatagca gtacttggtt caggagtaga caatcctctt ccaaaacaaa atttacattt
     2941 atcaaataaa atattagaaa atgggggatt attattatca gagtataata ttaactcgac
     3001 agtagccccg taccattttt ctaatagaaa tagaattatc agtggtttaa gtgatggagt
     3061 agttgttgta gaagcagcaa taaaaagtgg tgcactaatc acagtggatt ttgctcttga
     3121 acatggaaaa aatgtttttg caatacctgg taatataaat tctcaaatga gtagaggttg
     3181 tcataaaatt ataaaagaag gtgcaaaatt aattgaaaat atagatgata ttttaaatga
     3241 atataacata tttaatatta ttgataaaaa aataaatcaa aaatatgata atataagtct
     3301 aaatgccaag tctaagcaaa taattgaagc tataaaaaga gaaggaaact tgcatataga
     3361 tagtatttgt gattatactg gtatagaaat aaagtatgta aattcaataa tcaatgaatt
     3421 agtactaaat gagttagtag tagaaatgaa taataaaacg tacagtttaa atgtataaat
     3481 taagattagg tagtgggggt gtatggtttt atggccaaaa cattagtcat cgtagaatcg
     3541 cctgcaaaag ctaaaactat agaaaaattt ttagggaaaa gtcattacac agttaaagca
     3601 tcagttggtc atgtcagaga tttacctaaa agtaaattag gtgtagatat agaaaataat
     3661 tttgaacctc aatatataaa tataagagga aaaggcgatg taataaaaga attaaaaaaa
     3721 gaagctaaaa aatctaaaca agtatatcta gcaactgacc ctgatagaga aggtgaagct
     3781 atatcatggc atttagctca tatactaaat ttagatgaat ctgaggattg tagaatagag
     3841 tttaatgaga taactaagga tgcaattaaa aaagcaatta aacatcctag aaatattgat
     3901 ataaatttgg ttgatgcaca acaggcaaga agagtgctag acagactttt aggttatcaa
     3961 ataagtccta tattatggca aaaggttaga aaaggtctta gtgcaggtag agtgcaatct
     4021 gttacaacaa agttaatttg tgacagagaa aaagaaataa aggcatttat tccaaaagaa
     4081 tactggacaa tagatgttga ggctaagaca gtaaaagaca aagatataac tttgaaattt
     4141 tatggtaaaa atgatgaaaa gattgaatta gaaaatgaag aagctgtaaa tgaaatacta
     4201 aaagaaatgg aaggtaaaga tttaaaggtt gagaagatag aatctaaatc aagacgtaaa
     4261 tcagctccaa aaccatttac aacaagtatg cttcaacaag aaggagcaaa taagttattt
     4321 tttactacta aaaaaacaat gatgatagca caagaattat atgaaggtat cgacatagaa
     4381 ggtgaaggta ctgttggtct tatatcatat ataagaactg actctaaaag aatatctgat
     4441 gaagcaaaag aaaaagctaa gggctatatc gtaaacaatt taggagaaaa ctactataaa
     4501 aacactggtg ataaaaaaga aaaaaaggat actaaaaagg ttcaagatgc ccatgaggca
     4561 ataagaccaa cctcagttga tagaactcct gagagtataa aagcctcatt gagcaaagac
     4621 cagtacaagt tatacaattt aatttggaga agatttgtag ctagtcaaat ggaagattca
     4681 gtgtttgata tactaaatgt agaatgtaaa ataggcgata ttgtatttaa ggcaactggt
     4741 tcaaaaatga aatttgatgg ttataccaag gtatataatt tttcagaaag agaagacaaa
     4801 attttaccaa gtatagaaaa aggagatata ttaaatatag aaaatatatt gccagaccaa
     4861 cattttacac aaccaccagc aagatataca gaagctagtt tagtaaaaac actagaagaa
     4921 ctaggtatag gtagaccaag tacgtatgct ccaacaatag ctactatact gaatagagag
     4981 tatgttgaaa agcaaggaac aagtctatgt ccaacagaac ttggaataat agttactgat
     5041 attttggaaa ataatttcca taaatttata gatgtagatt ttactgctga tatggaaagt
     5101 aaacttgatg ttatagaaga aggcaataca gattggaaaa agattgtatc agaatcatat
     5161 gcaccactta aagaggctat tgaagaagct cttgaaaata tagaaaaagt aaatatggat
     5221 gaagaaactg atgagatttg cgagaactgt gggtctaata tggttatcaa atatggtaga
     5281 tttggaaagt ttatggcttg taaaaactat cccgattgta aaacaactag accaattatg
     5341 aataaaattg gtgttaaatg tccaaaatgt gaagaaggag atattatact tagaaaatct
     5401 aaaagaggta aagcttttta tgggtgttct aattatccaa actgtgactt tgtagcttgg
     5461 aataagccaa caggagagtt ttgtgagaag tgtggttcat atatggttga aaaagtgact
     5521 aaatctgaaa caaaaacagt gtgttctaat aaagaatgta ataaagagac aaaagagcat
     5581 aatgacggaa aagagtgaaa attgaaaaaa atcacataat tctcttgaaa aaggttccaa
     5641 tctatgataa tctttcaagt gtaaacaact aatagaaaaa taaattttca ttaaatgtga
     5701 aaataatatt agaaaatata aaaggttatt aaaaggccta aatttcatga ggagatgatt
     5761 aaatggcaag tgaagtgtta caaaaaacaa ggaaaataaa taaaacatta caaacaagtg
     5821 gtggaagcag tgtctctttt gatttactgg ccggagcatt gggcgacgtt ttaagttcta
     5881 atgtttatgt agtaagtgca aaaggtaaag tactaggtct tcatttaaat gatgttcaag
     5941 acagttcagt tatagaagat gagtatacta agcaaaagaa attttcagat gaatatactc
     6001 aaaatgtgtt aaaaattgat gaaacattag aaaatttaaa tggtgagaag atattagaaa
     6061 tctttcctga agaacatgga agattacaaa aatatactac agtagttcca atattaggaa
     6121 gcggtcaaag attaggaaca ttggtacttt caagatattc aaattcattc aatgatgatg
     6181 atttagtaat agctgaatac agtgcaactg ttgttggtct tgaaatatta agagcaatag
     6241 gtgaagaatt ggaagaagaa atgagaaaga aagctgtagt tcaaatggca ataggcactc
     6301 tgtcctactc cgagcttgaa gcagttgaac atatttttgc tgaattggat ggaaaagaag
     6361 gtctacttgt agcaagtaag atagctgata gagttggtat aactaggtct gtaatagtaa
     6421 atgcacttag aaaatttgag agtgcaggtg tgatagaatc aagatcatta ggtatgaaag
     6481 gtactcatat aagaatactt aatgacaaac ttacagatga attaaaaaaa ttaaaaaaca
     6541 atcaataatc tatattttat aggtttagat tagaaaaggt atctatttca aatagatacc
     6601 ttttttagac gaattattaa ggtaatgata agtatattaa aaaggagtga gaaaatgcct
     6661 ttagcagata aaataagacc aaaaacaatg aatgatgtaa taggtcaaag tcatataata
     6721 ggtaatggaa aaatattgtc taagatatta caatctaatt ttttaccaaa tatgatattt
     6781 tttggtcctc ctggtgttgg taaaactaca gtagcggaaa taatagcaga aagaagcaat
     6841 aaaagcttct ataaaataaa tgctactaat tcatctttag aagatataaa aaaggtgata
     6901 tcagagcttg gaagtataaa taatgtaaat ggagtcctat tatatataga tgaaatacaa
     6961 agttttaata aaaaacagca acaatcaata ttagaattta tggaaaatgg gagtataact
     7021 ttgattgcta gcactacaga aaatccatat cattatgtat ataaagctct tttaagtagg
     7081 tctactgtat ttgaatttaa acctttagaa aaacttgatg tagaaaaagg actgaaaaga
     7141 gctgttgaag tattaaatga agatagctat atggatattg agtgtaataa taatgctatt
     7201 gaagatatag caattctttc tgatggagat atgagaagag ccttaaatat tttagaagtg
     7261 gtagtctatt caactaaacc aaataaggat aatataactt atatagattc agatgtaata
     7321 agggcatcta catttaataa aattataaac tatgacaaaa atggtgatag tcattatgat
     7381 attttaagtg catttcaaaa atctataaga ggaagtgacc cacaggcatc tatacactat
     7441 ctagcaagac ttataaaagg tggggatttg ataagtatat gtaggagact tttagtaata
     7501 gctagtgaag atataggttt agcttatcca aatgctattg taattgtaaa ggcatgtgta
     7561 gactcagcta tgcaacttgg atttccagaa gcgaaaatac cattagcaga agctactatt
     7621 cttttggcta catctccaaa gtctaattct gcatgtatag caataatgaa agctatggat
     7681 gaactggata aagagtttgt taaggatata ccaaatagta taaaggattc tcactattct
     7741 ggttctaaag aaataggtag gggttgtgga tacaaatatc ctcataattt taaaaatcat
     7801 tatgtaaagc aacagtattt accagatagc ataaaagata gtatttatta cataccacaa
     7861 gaaaataaaa ctgagaaaaa tataaaaaaa tatttagaat atctaaatag tgatttttag
     7921 actgaacttt atgtatcggg ggtagatatt atgattataa aacttaactc aacttatcac
     7981 agtagagtta tgaaatactt aaaaaaagaa cctgagtaca atttgtttat aataggggat
     8041 attgaaagat atggatatgg aaataatttt ttaaatatat gggcagatgt gggtgaacat
     8101 ggtgaaataa aggcaatatt acttaaatat tttgaattta tgatatttta ttctgatgga
     8161 gagtatgatg ttgaaggttt ttataatcta cttcgtaata ctaattacga agaaatatct
     8221 gggaaaatat gtgctgtaga tgctttagca aagagattag gacttaataa tttaaaggta
     8281 gttgattttt gcaaacttca aactaaaaag tttttgatag ataataattg taatgcaaag
     8341 gttaaaagaa ttaggcttgg aaatctaaaa aagacagtga aactttatga cttaatagat
     8401 gaatttcaca gtacaacttt agagaattta aaaaatggac taaggacagg tagaggatat
     8461 tgtatagaga ttaacaaaca ggtggtgtca atggcaaaga gtacttcaga aaataggact
     8521 catgcaatga taattggagt aggaacacat cctaaatata gagctaaagg acttgctaca
     8581 aaatgcctaa ttaaactatg ttcagagtta ctgagagaaa acaaaattcc ttgtttgttt
     8641 tatgataatg aagaggctgg aaagatatat aaaaaactag gatttgaaaa cattggaaaa
     8701 tggggaattt attcaaaata aaaaattaaa attaatcttg acaaaattag tagggtataa
     8761 taaaattatc ttgaaagtaa ttcctactaa aacagtatga attagatttc tatatagagg
     8821 tgataatata tgaagttgtc tactaaaggt agatatggac taaaagcaat gtttgaatta
     8881 gcattaaatc aagacaatgg accagtatca ttaaaattta ttgctaagaa gcaaaaaata
     8941 tcagatcagt acttagaaca aatattttca tctttaaaaa aatcgggtct agtaaaaagt
     9001 gtgagaggtg ctcaaggagg ttatttgctt tcaaagaatg ctgaagacat aacagtagga
     9061 gatatacttg tagtattaga aggaccagtt gcattatctg actgtgtact agatgaagat
     9121 gtatgtgaaa actcaaacat gtgtgtaaca aaaatagttt gggaaaagat gaaaaagggt
     9181 atagaagatg ttatagattc aattactctt aaagatatga taaatgacta taacaaaaat
     9241 aaattagaaa atgatataac aaatattaaa aaatagattt ggagatgaat gtaatggaaa
     9301 aaagaagatt gtatatggat tattctgcaa caacacctat taaaaaagaa gtattggatg
     9361 caatgatgcc atacctaaca gattattttg gtaatgcatc tagttttcac acattcggaa
     9421 gagaagcaaa agatgctttg gataaagcaa gagaacaagt agcagccctt ataaatgctg
     9481 aacctagtga aatatatttt acagcaggtg gttcagaaag tgataactgg acactagagg
     9541 gtgtagctta tgctaataaa aacaaaggta atcatataat aacttcaaaa atagagcacc
     9601 atgcaatact tcatacatgt gaatacttag caaaacatca tggatttgaa ataacttatt
     9661 tagatgttga tagcgaagga aaagtagact taaagcaact agaagattca ataaaagata
     9721 ctactatact tataagcata atgtttgcaa ataatgaaat aggaactata cagcctatta
     9781 aagaaatatc cgaaatagct aaaaaacata agatattatt ccacactgat gcagtacaag
     9841 ctacaggtaa tattccagta gatgttaaag aattaggaat agatttgatg agtatgtctt
     9901 cacataaaat atatggacca aaaggtgtag gagctttata cataagaaaa ggtgtaagac
     9961 ttcataactt tgtccatggt ggagcacaag aaaaaagcaa aagagctggt acagaaaata
    10021 tacctgcaat agttggatat ggaaaagcag cagaattagc taaggaaaat atgcaaaatc
    10081 atgtagaaac tttaactcgt cttagaaata agttaataga tggtgtgtta gaaagaatac
    10141 cttacacaag agtaaatggt agcttagata atagattgcc aggaaatgca aactttgcat
    10201 tccaatttat agaaggtgaa ggaatacttt tattattaga tatgttagga attgctggtt
    10261 caagtggttc tgcatgtact tctggttcat tagacccttc acatgtactt cttgcaatag
    10321 gtttaccaca tgaaatagca catggttcat taagacttac agttggagat tttacaacag
    10381 atgatgatat agattatata ctagagaact taccaaaagt aatagaaaga cttagaagca
    10441 tgtcaccact ttatgatgat gcgaagaaac aaggtttagt aaaatagaca taaagataaa
    10501 gcataaaaaa tagacataaa ttgagtagga ggaaaagata atgcaatata gtgataaagt
    10561 tatggaacat tttatgaatc caagaaatat gggagaaatt gataatgcaa gtggtgtagg
    10621 tgaagttgga aaccctacat gtggagatat aatgaagata tttttagaca tagatggaga
    10681 tgtaataaag gatgttaagt ttaaaacatt tggctgtggt tcagctatag caagttcttc
    10741 tatggcaact gaaatgataa aaggaaaaac tataaaagat gcattagaac ttacaaataa
    10801 agctgttgca gaagctttgg atggtttacc accagtaaag atgcattgtt cagttttagc
    10861 tgaacaagct gtaaaagcag cccttataga ttatgctcaa aagaacaata tccatatacc
    10921 agaattggat ggatatgtta tagatgatgc tcatgaccat gatgttgaag aagaagaata
    10981 aaaataagtg attgtgttat gagaagttta caatgattaa aaagaagtac taatgatata
    11041 attaggacat aaaaaatagc tgtttttaaa atggctattt tttattgcct aaattaagta
    11101 ttttaacttg atttagaggt taattagtta acaaaataat ccataagatt caaataataa
    11161 agatgattat ttttttagaa aatagaacaa gctatatttt aaataagtac aatacttgct
    11221 ctatatggta taataataag taatgcaaaa gatgaggtga aatttgttta tgaataaaaa
    11281 agtaatgata ggtatgagtg gaggagttga tagctctgta gctgcatatc ttttaaaaca
    11341 acaaggatat gatgtcattg gtgttactat gaagttgtgg caagatgatg atgttgttga
    11401 aattgaaggt ggttgttgct ctttatctgc tgttgaagat gctagaaggg tagcaaataa
    11461 aataggtata ccattttatg ttttaaattt tagagaagtg tttaaagaaa aagtaataga
    11521 ttattttata gatgaatatt tggaaggaaa aactcctaat ccctgtatag cttgtaataa
    11581 acatataaaa tttgatgatt tttataagaa ggctagacaa ataggttgtg attatgtagc
    11641 tacaggtcac tatgcaaaga tagaaaagga tgaaagtaca ggaagatatt tgctaaaaaa
    11701 atctgttaca gataaaaaag accaaactta tgcactttat aatcttacac aagagcaact
    11761 agagcatact ttattgccaa taggtgacta tgaaaaagat agagtaagag aaattgctaa
    11821 ggaaatgggt atggcagtac acaataagcc tgatagtcaa gaaatttgtt ttgttaaaga
    11881 taatgactat gcaaattatg taaaaaaaca ttctaaaaag cgtattgaag aaggtttttt
    11941 tgtagatact aaaggcaata tacttggaaa acataagggt atattatatt atactatagg
    12001 ccaaagaaaa gggcttggaa ttacttttgg aaaaccaatg tttgtaatag atataaatcc
    12061 aataaataat accatagttc ttggagacaa tgaagattta tttaaaaagg aacttattgc
    12121 taaagatgtt aactttatat caatagatac gttagaagaa cccttaagag ttcaagccaa
    12181 aataagatat tcagcaaaac catcaccagc tactattcat agagtaggag aagatactat
    12241 taaaatagtt tttgatgaag ctcaaagagc tattactaaa ggtcaatctg tagtaatgta
    12301 tgatggagat attgtagtag gtggaggtat aatcgagaaa agtttataaa aacatctaaa
    12361 aaattaaaaa aataagcaat aaagtatatt aagagtaaat aaagtttata aaataaattt
    12421 attgtatatg aaaatatagt attgattaat tttgtaaaat ttagtaatat aattagtata
    12481 ttaattaaaa aacaaataca gtgataagga atagtaaaat atttgatgtc ttacagagag
    12541 agggaaatgc tggaagccct tagaatatga tatttgaagc agccttttag tagcaatctt
    12601 gaacaattta tcttttataa agaagattta agtagagatt gacggtagtt acgttatagc
    12661 taaggttttc cgaagatatc atactttgta tgataattag ggtggtaccg cgattgtcct
    12721 cgcccctata aatttattta tagggacgag gttttttatt taaacgaaaa aataaaattt
    12781 attaggagga acatgatatg gaaaagatgg gattaaatga aataagaagt aagtttttag
    12841 aattttttga gtcaaaaggt cattatgtag caaatagtta ttctttagta ccaaacaatg
    12901 ataagagttt gttacttata aactcaggta tggcaccttt gaaaaactac ttttcaggtg
    12961 tagaagtacc tccaagtgtg agaatgtgta catctcaaaa atgtataaga acaggagata
    13021 tagaaaatgt aggtataact gcaagacatg ctacattctt tgaaatgatg ggtaatttct
    13081 catttggaga ttactttaaa agagagtcaa tcaaatgggg atgggaattt gttacagaat
    13141 ggctaaatat accagaagat aagatatggg tgactgtata tgaagaagat gatgattctt
    13201 atgatatatg ggcaaaagaa atgaatttcc cagaagaaag aatggttaga cttggaaaag
    13261 atgataattt ctgggaaata ggtacaggtc cttgtggtcc ttgttcagaa atatattttg
    13321 atagaggaga agaatatgga tgtgacaatc cagactgtaa accaggctgt gattgtgata
    13381 ggtatttaga attttggaac catgtattta ctcaatttga tagagatgaa gaaggaaatt
    13441 atagtctatt agaaaacaag aatatagata caggtatggg tcttgaaaga atgggatgta
    13501 ttatgcaagg cgtagacact atctttgaag ttgatacaat taaatctata ctagaagcag
    13561 ttgagaagtt aacaggagta aaatatggag agaatccaaa aaatgatata tcaataagaa
    13621 taataactga ccacataaga gctgtaacat tcttagttag tgatggagtg cttccatcaa
    13681 atgaaggaag aggatatgtt cttagaagac tccttagacg tgctgctcgt catggtaagt
    13741 tattaggagt aaaagaatta tttttacaga aactaataga tgaggttata aaagtaaatg
    13801 ataaagcata tccagtttta gttgaaaaag aaagttatat taaaaaagta gttggaatag
    13861 aagaagaaaa attcaatgaa actatagacc aaggaacaga aatattgaac tcttatatag
    13921 aagtattaaa aaatgaagga aagactgtcc taagtggtca agaagctttt aaactatatg
    13981 atacttatgg cttccctata gacttaacta aagaaatatt agaagaagaa catctatctg
    14041 tagatgaaga agcttttaat gaagaaatgg aaaagcaaaa agaaagagct agaaatgcta
    14101 gaggaaatat ggatggagaa agttggaagg aagaccctct atcaaaatta gaatctacag
    14161 ttgacagtac atttaatggg tatagtgaaa tttatggtga aggaactatt gaagctatag
    14221 ttaaagatga tgagctagtt caaagtgcag aagaaggcga taaggtatct atagtactag
    14281 ataacactac tttctatcct gaaggtggag gacaagttgg agattgtgga ttgataacta
    14341 atgaaaactt agttttagaa gtattaaata ctaaaaaagg tgctaataat agtataaaac
    14401 atataggtat aataaaatca ggaagaataa gtaatgggga caaagtaaag acactcgtag
    14461 atagagaaac tagaatgtca gctgcaagaa atcacagtgc tacacattta cttcataagg
    14521 cattaagaga agtattagga gaacatgtta atcaagctgg ttctttagta actccagaaa
    14581 gacttagatt tgatattact cactttgaag caatatcaaa tgaagaatta aaagtaatag
    14641 aagaaaaagt aaataatgtt attttatcat ctttagacat aaaatgtgat attatgaata
    14701 taaaggaagc taaagaaaaa ggagctacag cactatttgg tgaaaaatat ggtgatgagg
    14761 taagagtagt ttctatggga gattattcta cagaactttg tggaggaact cacttgacaa
    14821 atacttctca agtaggaatg ttcaaaatat tatctgaagg tggagtagca gcaggtgtaa
    14881 gaagaataga agcaataaca ggaaaagctg tttatgaata cctaaaagaa agagatggaa
    14941 ttatctctga agtttgtgta aacttaaaat ctaaagaaga taatttaatt caaagaataa
    15001 gttctttatt agaagaaaat aaaaacttat ctaaagaatt gcatgatatg aaagctaaga
    15061 tgagtttaca atcagttgat tctatttttg attctaaagt tgaagtaaat ggagttaatt
    15121 tgataactaa taaatttgaa ggtatggata tggatacact aagagaaaca gcagataatc
    15181 taagagataa gcttggttct ggtgtagtag tacttgcaaa tgtagtagat gataaagtta
    15241 actttgtagt tactgccact aaagatgtat tagataaggg aatacattca ggtaatattg
    15301 ttagagaagt tgcaaaaata gctggaggaa aaggtggagg aagacctaat atggcacaag
    15361 caggagctag tgatgtatct aaggttgacc aagctttaag ctatgcaagt gaggttatta
    15421 agacacaagt taaataacat tcactcaagg aggtttttag tttggaaaaa gatttagact
    15481 acactatgaa atttgaagga ataccagaag ataggatgag tgtaggagat actattgatt
    15541 ttgtatataa agcattagtt gaaaaaggat ataaccctat aaatcaaatt atagggtatc
    15601 tcctttctgg tgattctagc tatataacta gtcataaaaa tgcaagagct ataattaaaa
    15661 aatttgaaag agatgagata cttgaagaag taatcacgca ctatctgaat agaaagtagg
    15721 tcaaataaat gagaaaaaag attatgtcgt tgtttgcaat agtcattatg atttttgtat
    15781 caactgctag ctatggtttt gctgaagaaa aaggcaaggt catatttatt gatatgaata
    15841 ggaccaatct tggaagtatg atgaatattc caatcttgaa aaatgagata gaaaagagag
    15901 gctatgtagc tctcatgaat ataagagggg atcaaggtac tgatgataga aggtcttgtg
    15961 caagtatggg tgcaggaaca agagctagtg taactactga agactatatc aattttcaaa
    16021 aagtagacca agatactgct aaagcttttg aagtcgcaac aggtcaaaaa gctaaagaaa
    16081 taaatgattt aggcattaat agatctataa atgaaaatct tgagtatgga gaatatggag
    16141 caaatttagg gtcattagga aaaactttat cagaaaatgg tttaaagaca tctgtaattg
    16201 gaaatgctga tataattgaa aataatcaat tagttaaaaa cagaaactta tgtttagtag
    16261 ctatggacca atatggaagg attgattcag gtaatattga taatattaat aagaaagatt
    16321 ctaaaatgcc atttggaata tctacagatt atgataaatt actagatgaa actaaaaaat
    16381 cctataaaaa tagtgatgct atatttgtag aacttggaga tacatataga ttagatatgt
    16441 atagattaaa tctaaatgat aatacttatg atacaatgaa gaaaaatatt gtaaaaaata
    16501 taaataaata tcttgaacaa gtattttcta tggttggaga aaatgacact gtttatatag
    16561 caagtgcatt tccaagtgac ctagattata agaataagag aagactttct ccaataataa
    16621 aatttagtgg agaagggaaa ggtctactgg aatctgccac aacaagaaag gctggaattg
    16681 ttgccaattt agatgttgga gtagatatac taggtacatt tggtcttgaa aataaagaga
    16741 tggtaggtag aagttatact ttagtaaata aagaggacaa tattagctat ctaaaatcac
    16801 tttatgaaag gatagtgtct atatcttcaa taaggtcaac tattataaat ggctttgtag
    16861 gcgtaatatc tgcttcttgg gtaattgcca tgtttgcgat tttctttaga aattatatgc
    16921 cacataaaga gcgtgtattc aaagtactta aggagtttat aaaattaggc ataataatgc
    16981 cactatcatt tatgttagct cctttgatga attttaaaac tccaatttca atatctttgg
    17041 gaatatttgc aactacgcta atattatact tgttaggtag aaaattattt aaggacaatg
    17101 atataaagca catgggattt tttgcaacac ttactatttt agtcatagtt atagattctg
    17161 tatttggaac atacttaatg caaaataaca taatgagtta tgatgctgtc ataggagcta
    17221 ggtactatgg tgtaggaaat gaatatgaag gtgtaactat agcaagtgca gtatttggct
    17281 tagcagtatt attacattat aagaaggtat ctaaattact tgttgtaatt ttttcattaa
    17341 taatacttat aactagtgca tatccttcaa tgggtgcaaa tgttggtgga gctatatcag
    17401 aatgtgtagc atatttgttg tttataatgc ttatatatga cattaaaata gattttaaga
    17461 aagctgtatt attagctgtt tcagctgtag ttgtcgtttt tgcatttgca gctttagata
    17521 tactttcagg tagtgaatct catttaggta tgtttgtaca gagaattttc ctaaatggac
    17581 caggagagat attacaaaca tttggaagaa aaattcaaat gaatatgcaa ctagcacaga
    17641 caagtgtatg ggtaaatatt ttacttgtag gaattggagt aattgcagtg cttatattta
    17701 aaccatctag acactttaga aagataatga ataattttcc aatcttgttt aaagggttta
    17761 ttgcatctat ggttggttgt ataattactc ttttagttaa tgattctgga atagttgctg
    17821 catctacagc atctatatat atacttatac cactaataat aataagtata aatatgataa
    17881 tatttgaaaa aaataactaa aaaaattttt actgttcata taggatttaa ataaaaaatg
    17941 caatatgatt attaatgtaa actggatgct tacataaaaa atcatattgc aatttttatg
    18001 attgataatg taaaattcta tgaagcagta agcctgtgac cttagttatg agaggttcag
    18061 aatatgtatt taatctatag aatataaata gataaaggag gaactatgtt agatggaaga
    18121 ataatgggtc ttgatgttgg tgataaaact attggagttg ctgtgagtga tttgatggga
    18181 ttaactgcac aaggtgtaaa aacaataaaa agagttggca agaaaaaaga tattgaagag
    18241 ctaaaagcaa taataaaaga aaaacaagta aataaaattg tatcaggatt accaaaaaat
    18301 atgaatggaa ctttaggtcc acaaggagaa aaagtaatca agttttgtga attggtaaaa
    18361 gcagaaacag gtattgatgt agagttttgg gatgagaggc tttctacagt agcggcagag
    18421 aggtctttat tagaagcaga tgttagtaga caaaaaagaa aaaaggttat agatatgttg
    18481 gcagcagtaa taattttgca aggatattta gattttaaaa taaattcata aaagaactat
    18541 aaaattgaat acttatgata tataatataa ataataaaaa taaaaataaa tttgaggtga
    18601 atgacattat ggaagaaaat ataataaatt taatagacga aaatggcgtt gaaagccaat
    18661 ttgaaataat attaacatta gaagcagaag gaaaagagta tgcaatatta atgcctttag
    18721 atgatgaaga agctgaagaa gctttaatct ttagaattga tgaggatgaa gaaggtgaaa
    18781 tcttaatacc tttggaaagt gatgaagagt atgaaactgt tgtagctgtg tatactgcta
    18841 taatggaaga agaaggttta aattacgacg aagatgaatc aaatggactt aactagataa
    18901 gtaattaagt ttgtatataa aaatcagata tttattatat ttgctttaat taaaccttat
    18961 taattgtaaa agcatttata gtatatatct gtttttttgt tttttattaa aaataccaaa
    19021 aaatttatga attttggtga ataatatatc ttttatgggt atatatttat attatgagaa
    19081 taaattaaat ttatttaaat gtcttgacaa aaaatgaatt atcaattaca atattattta
    19141 ataaagatta tcaattgaaa atagtaaggg tgatgttatg gcaaatacaa tggatttatt
    19201 aaaagacaag ttaaaagaaa ctggttttaa gattacgcca caaagaagag caatagttga
    19261 aatattgctt aaacatgacc attcacatct aagtagtgag gaaatctatg atttagttag
    19321 ggttgactgt cctgaaatag gcttagctac tgtatataga acaatgcagc tattggatga
    19381 aataggatta atatcaaaac taaacttaga cgatggatgt ataagatatg agattagtct
    19441 acataaagaa gactgtcata atcatcatca tcttatttgt aaaaattgtg gaaagataat
    19501 ggaagctaaa gaagaccttt tagacaatat agaaaaagag atacaatcat tgtacaaatt
    19561 taaaatactt gatcatgatg ttaaatttta tggactatgt gacgagtgta atggagtaag
    19621 cgattcagaa gaataaactt ctattgctta atgtcgatgg aagaatagta tagaactttt
    19681 atattctatg ctattcttcc attttttatt ataaaccatc tataaaatgc aaatatacag
    19741 ttttcaaagt gattatagtt ttaatattga aaatataatt aatcctataa gtacaaaaat
    19801 gaatgatttt tctatgaaat tactaaatgg tcctccaaca gttaaaaacc ctaaagaaat
    19861 tttcttttcg cttaggggat aaaaaattgg tattccttgc tttgtaaata aatctcctaa
    19921 aaacatatgg cttgcataac caatcgtacc ataaaaagat aaattattaa tattagtgat
    19981 taattctatc tgttttagta aaaaatatac tattatagtt gcaaatatgc tatgagaaaa
    20041 acttctgtgc tttaaccagg ggaaaattga caacattaga caaaaaattg taaaatatat
    20101 ttcaacttct atgatgtata agcatatagc taatagtata aatattaatg atagaaaaac
    20161 ttttcttaga aatgtatggg ttagttttga ttcaataatt ataattgcaa caaatgtaat
    20221 tattgcgctt aaataaaaat tatcatttat atttattgaa ataaagaaaa taataatatt
    20281 aacagcatat ataaaaattc tatatatgta tttggataca ttgtttttta gaatgaaatt
    20341 tgagaccata gaattagatt tatccaaatc gggtagtaca gcaaaagtag ctgaaactaa
    20401 aatatcaact aaagatatag gaattttaaa tattaaagat gtctggatag ctgttaagat
    20461 tcctattgca caatgagttt taccacgcat aaatcctcct aaattatccg atattaaatc
    20521 atataatatt tagaggatat caaaataaaa taggtttgtc aaaataatac gttaaatgta
    20581 ttttaaatat agcttaaaat atgatacgaa ttatggtaca ataagaataa ctggtagcga
    20641 gtgcgtgatt tgatattatt tatgattgta gaacgtgtta aaaaattaaa tagacagaag
    20701 gagatgatgc aattgttcaa aaagaacacc aataagataa aggtaatggc cttgggtgga
    20761 cttaacgaag ttggaaaaaa tatgactgtt gttgagtata aagatgaaat aattgttata
    20821 gatgctggac ttagttttcc agaggatgaa atgttaggag tagatatagt tataccagat
    20881 ataacttatt tagtaaaaaa tagggataaa ataaagggta tatttattac acatggacat
    20941 gaagaccata taggagctct tccatatata ttaaagaaaa taaatgtacc tgtatatggg
    21001 gcaagactta gtataggtct tatacaagta aaacttaaag aacataagat gaataatgtt
    21061 aagttaaatg ttataggtcc tagacaagtt ataaagcttg ataatatgga agtagagttt
    21121 ttgaaaaata accatagtat accagatgct tactctattg caatacacac agaccaaggt
    21181 ataatatacc acacaggaga ttttaagatt gacttgactc ctattgatgg agatgttatg
    21241 gatatgcata gaatctgtga gttgagcaaa aaaggagttc ttttaatgct ggctgatagt
    21301 actaatgcag aaaaaccagg atttactatg tctgaaaaga ctgttggggt aggtcttgac
    21361 gaattatttg caaaaggaaa tggcagaaga attatagttg ctacctttgc atccaacata
    21421 cacagattac aacaaataat aaatactgct gagaagttta atagaaaagt tgctatatca
    21481 ggtcgctcaa tggtcaatgt agttggagtt gcaaaagaat taggatatct agatatttct
    21541 gatgacatgc ttatagattt aaatgatata tgtaagtatg aagatagtga attagtgata
    21601 ataacaactg gttcacaagg tgaacctatg tcagctcttg ctagaatggc tttttcagag
    21661 cacaaaaaag tagaaataaa gagtggcgat ttagttataa tatctgctca tccaatacca
    21721 ggaaatgaaa aattaatatc aagagtaatc aatttcttat ttgaaaaagg agcagaagta
    21781 gtatacagtg atatagctga tatacacgtt tctggacatg cctgtcaaga agaattaaaa
    21841 cttatacatg cattagttag accaaagttt tttatgccag ctcatggtga atatagaatg
    21901 ttaaaaagac atgctgaaat agctgaacag cttggtatgg ataaagaaaa tatttttgtc
    21961 atgcaaacag gagatgtttt agaattagat aaaaactctg ctaaggtagc aaatcgtata
    22021 caaacaggaa acatattagt tgatggtcta ggagtaggcg atgtaggtaa tatagtttta
    22081 agagatagaa agcatttatc agaagatggt cttatgatag ttgtagttac tatttctaag
    22141 gatgagggta aagttttagc aggtccagat ataatttcca gaggattcgt atatgtaaga
    22201 gaatcagaag atttaatgga tggagcaaag gatataatta agaatgttct aaatgaatgt
    22261 gaagagaaaa atattaaaga atgggcttat ttaaagaata atattaaaga aaacctaaaa
    22321 gaatatttat atcaaaaaac taaacgaaat ccaatgatac ttcctatcat aatggaagta
    22381 taatataaaa aaactataaa tttgaaaatt agacctcttg taatttttaa agtaatatca
    22441 aaaatccaat tgatattatc ttaagaatta caagaggtct ttttaatact tgatttaaaa
    22501 aaatatatat attacataaa ataccaatta taacaatctt ttattagtaa aaactactta
    22561 tatataaatt ttactgatag gaggattctt atggatgatg tttcaagaca aaatgctata
    22621 aaagctttaa aacaaacaaa aatggaaata gcaggagagt atggaatgaa ttatgaagat
    22681 gcttttgaaa taatagaaaa tgcgtctaat aaaggtgttt tagaaggtta ctttaaaaag
    22741 cttgaaaaga aaaaaaattt aggtcaaggt atatctaggc atttagaata aaaaaagtta
    22801 aatgtgagaa aataagttta aataaacttt aagaggtgac atcgatgaaa aaattagcta
    22861 gtactgcttt ggctatatta attgcgctta ctcccttaag cttttctttt gcaaacaata
    22921 aggaaaatgc tgatgccaac caactaaata tatcttcaaa atcagcaatt ttgatggatg
    22981 ttggtagtgg acaaatttta tatgaaaagg atgctcataa aaagcttcct cctgctagtg
    23041 taactaaggt aatgactatg ctacttatag tagaagcttt agattcaggc aagattaaac
    23101 ttgatgatga agttcaagta agtgaaactg catctagtat gggtggtagt caaatattcc
    23161 tagagccagg agaaactcaa aaggttgata cattgttaaa aggtatagct gttgcttctg
    23221 caaatgatgc ttgtgttgct atggctgaac acttagctgg aagtgttgaa gggtttgttg
    23281 atagaatgaa tgctaaagca aaagagttaa atatgaatga tactcatttt gcaaatacaa
    23341 atggacttcc agttgcaaac cactatacat ctgctcatga tatagcttta atgtctagag
    23401 aactattaaa acacgaaatg ataagtaaat acttaactac atggatggat aaggttgtag
    23461 tagggaagaa acaagttaca gtaggtcttg caaatactaa caaacttata aagcattatc
    23521 aaggagcaac tggtgttaaa actggcttta ctcaagaagc gaaatactgt ttatcagcat
    23581 ctgcaaagag aggtaatact catctagttg ctgcaacttt aggagcagag acttctccag
    23641 aaagatttaa tgatgcctct agccttttaa cctatggatt tgctaattat gaaagtgtta
    23701 agttatgtag taaaggtgat aatatagcaa cacttacatt ggataaggct gatgaaaaca
    23761 aagttaaatt ggttgctaaa gaagatttaa atgctcttat taaaaaagga agttctaaag
    23821 aatttgagaa gaaaattgaa atagtaaaaa atcctaagat gccaattaaa aaaggaactg
    23881 ttttaggaaa gataaagata tgtaaagata aaaaagtaat aggcgaagtg gaattaataa
    23941 atactaaaga tataaataag gcaagctatc tacaaatgct tcaaagaata attgataata
    24001 tgatataaat aattatcaga tgaaatataa ttataataca caaagatatg attataatac
    24061 acataaaaaa tacccttatg taattatttg ccataggggt atttttattt actatataga
    24121 agtattttat aatcttatga tttttataga aatatagaaa agtttatgta tcttaaaata
    24181 tcatttgatt taatatcata tatagggttg tttaacaatt atctaagtaa aggcatacta
    24241 ccagtaagtt tattcacttt ctttttattc ccataaattg ctatcccaaa atactgtaac
    24301 tcatcttctg gaacactagc aatcttttgt gtaaattctt cataaagatt gcaactttgt
    24361 gctacatctg aaaaatctac aacagttaaa tcgttaaatt ccaaagtata taatttttta
    24421 cgtaaatctt ttattatttc tttgtttcct tttaaaatag gtacaggaat gtcaataatt
    24481 cctaagtggc tattacctgt tttgtcaatt acatctggcc caacagtttc tggggcatgt
    24541 tttcctagtg taattcccat tatagctgct gtattggata taattcccat tggtaaattt
    24601 tcgtctatta ccatgacaca ttttgaattt ttattttcca tttttatttc tcctttttac
    24661 cttatttaaa gttgtttgaa tcatcattta taaatatatt ttgatactgc tttggtgtaa
    24721 gaccaataaa attcttaaaa aagtttgtaa agtgactttg gtctacaaat cctgtttgta
    24781 tcgcagcatc tataggttct acgccttttt ctaaaagctt tttagctttg tttacccgta
    24841 tattttctag gtatctatat ggtgtaatac cttttaattt cgtaaaatta cgaagtagag
    24901 agtacttatt catacctgct atagtgctta attcgtcaag tattatatgt tcagcataat
    24961 tattttctag ataatcacat actgcttgaa tttctatatt tgtattttcc aagttagatt
    25021 gcaaatttgg ctctgtatgt tcttcaatta attgttcaat taggaagaaa aaaagctctt
    25081 cctttttaaa atccaattct tcttccatga ttatatagtg taattcttgt agtagaggta
    25141 ctaactcact gcgaaatata acaggttgat taaattttgg taaataattt ttacctgtaa
    25201 tttcaaagac ggtttttttc attatttctg gcttaatatt aatacatctg taatcaagta
    25261 ctttatcatc tatttgttca caagtatgac tatcaaaagg gttaaaaagt agcaaatctc
    25321 cagtacttgt ggtatactct ttatttttac aagataaata tctttgacct ttttctataa
    25381 aaccaattac ataatgttca tgaaaatggt ttgggaattt ttgcattatg cctttaaatc
    25441 tatatgcttc aatttttaat tccctatcaa agcatactgt gcgttcttct tgtctcactt
    25501 aggtaacctc ctttcatgtt atacaaagtg taacacatat ttttttatac ttcttgtata
    25561 atattgacta agagacaata atgtcaattc atgtcaatat aatattacac ttacagtagg
    25621 tgtaattatt atattttcac aatgaatatg atataataat aaaagttata aaataaaaag
    25681 caaattttaa ttttatgcct agaagttaaa attattataa tgtaaaataa ttttgattat
    25741 aagctattta attgttataa taatattaaa aatttaattt aggagatgta cattaatgtt
    25801 aagtatgaat ataggagaaa tagtagcaag tttagttggt atagctatgg caatatcaat
    25861 acatgagttt ggccatgctt attcagctca cttattggga gatgatacag ctaaagctta
    25921 tggtagaatg acattaaatc ctgtaagaca tgttgaccca ataggtcttt tggctatgtt
    25981 tatccttaag atagggtggg caaagccagt accagtaaat ccaaataact ttaaaaacta
    26041 taagatagga aacctgatag tttcacttgc aggcgttttt tgtaatgttt tgactgctat
    26101 actgtgtgta attatcaata agtatgtgca tatgtatgct ataaatacaa tagctgaata
    26161 tgtgttttta tatagtattg gatttgcagc ttttaactta cttccgatac ctccacttga
    26221 tggatgggga gttatatcta catttgtacc atataaatgg aatgaatatt tgtataaatt
    26281 tgaaagtatg agttatataa ttttattaat tgctttattt actggtatgt atagaataat
    26341 attaacacca atatatgcag tgttgctaaa aatagtatat ttatttgttt aatataataa
    26401 acagattaaa gagggattga tatgaagtat aatatacaat tacaagtcta tgagggacca
    26461 ttagatttac tttatgattt aataacaaag cataaaatag atataaagga tatatccata
    26521 atagatataa ctaagcagta tctaaattat ttgaaaatgc tagataaaat ggatttagag
    26581 ataactagtg aatttataac tatggcatca aaacttttag agataaagtc taaatatctg
    26641 ctttataagc aaaaagatga agaagaagac ccaagaatag aacttatgga aaagttagaa
    26701 gaatatagaa agtttaaggt agcatcacaa gatataaaag aaaatataac ttatgttaat
    26761 gagagatttt atagaaataa agaagagata attattgatg acaatgtgga tttagaagat
    26821 atatcaattg aagcaataaa aaatatactt ccatacatat ttaaagttaa aacatcacag
    26881 atagaaaatg ctaatgatga gaaactagat aaaatagtaa ggaagaaaat aatatctgta
    26941 gaagaaaaaa tattatatat aagagatatt ataaaagaga agattgaagt tacttttaca
    27001 aatattataa aatcatatga aaatgatgaa ataatagcta cttttttatc tatattagag
    27061 cttataaaag aaaaagaaat agtcgtagta caagatatat tttttgatga tattctaata
    27121 agaaaaagtt cggagtgtta aaatgaaaag agaagatata aagtatatta tagaatctgt
    27181 tatgtttgca tatggtgagc caataagtat aaaagaatta aactatataa taaataaaga
    27241 actttcatca aaagaaatag agattatgtt aaatttactt attgaggagt acagagaaca
    27301 aaatagaggt attcaaataa tcaagttaga gaataagtac caaatgtgta caaataaaga
    27361 ctatgcagaa tatataaaga agattattga accaaagaaa aagaaaagtt tgagccaagc
    27421 tacattagaa actcttacta taattgccta caaacaacca ataacaaagg tagaaataga
    27481 ggatataaga ggagtaaaat gtgataaggt attacaaact ttgtttgaaa atgaacttat
    27541 aagagaagct ggtagattga ataagatagg gaaaccaata atttataaaa caacagatga
    27601 atttttaaag ttgttgaata tagaaagtct tgaagaattg ccacctatag aaaattatca
    27661 agaagtggca acaaatgaat aaaaatataa aatcacaata atttagtatg taattttaaa
    27721 ttttaaaaga tttaaaatgc tctaagttgt tgtgtttttt tgtataaata taaaattata
    27781 attctcttaa aataaatatg gataattaag tataaatagt aattttttga tgataatata
    27841 aacat
//
LOCUS       DAEPHU010000057        27803 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 01A10CD0081
            SAMN05941466-rid12468953.denovo.057, whole genome shotgun sequence.
ACCESSION   DAEPHU010000057 DAEPHU010000000
VERSION     DAEPHU010000057.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941466
            Sequence Read Archive: SRR6291087
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 27803)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 27803)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068158.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 22:43:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,892
            CDSs (total)                      :: 3,805
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 87
            rRNAs                             :: 8, 1, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 55
            CDSs (without protein)            :: 55
            Pseudo Genes (ambiguous residues) :: 0 of 55
            Pseudo Genes (frameshifted)       :: 21 of 55
            Pseudo Genes (incomplete)         :: 28 of 55
            Pseudo Genes (internal stop)      :: 16 of 55
            Pseudo Genes (multiple problems)  :: 8 of 55
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..27803
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941466-rid12468953.denovo.057"
                     /strain="01A10CD0081"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            complement(130..324)
                     /locus_tag="KR231_002538"
     CDS             complement(130..324)
                     /locus_tag="KR231_002538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0004902.1"
                     /translation="MFQVINFLCLFCVGFLVLDVMIYFCKDAMDIFEGTTNVNKVKSI
                     NVWADRVRANSYSYENKIAK"
     gene            complement(633..2162)
                     /gene="lysS"
                     /locus_tag="KR231_002539"
     CDS             complement(633..2162)
                     /gene="lysS"
                     /locus_tag="KR231_002539"
                     /EC_number="6.1.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434963.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysine--tRNA ligase"
                     /protein_id="HBH0004903.1"
                     /translation="MKNNQQSNEEAQIQEDLSEVLQVRRDKLKKLQESGRDPFKESRY
                     DRTHYSMDIKDNFDSLEGKTTKIAGRIMSKRIQGKAGFIDIQDQEGRIQSYVRLDAIG
                     EEEYSVFSTYDIGDIVGIEGEIFKTKKGEISVKAKSVVLLCKSLQVLPEKYHGLKDQE
                     LRYRQRYVDLIVNPEVKNAFLIRTKALKALRAYLDDRGFLEVETPILNTIAGGANARP
                     FITNHNTLHIPMYLRIANELYLKRLIVGGFDKVYEMGRMFRNEGMDLKHNPEYTAIEL
                     YQAYADYTDMMEITENVIAHMAEVATGSMIVNYQGTEINFTPPWKRMSMEDCVKEYSG
                     VDFSTINTDEEALEVAREKGIEIKPGMRRGEVINAFFEEFGEDKLIQPTFITHHPVEV
                     SPLSKRNVEDPRRTDRFEAFANKWELANAFSELNDPIDQKGRFIDQLRKRELGDDEAF
                     EMDEDFLKALEVGLPPTGGLGIGIDRVIMLLTNSPSIRDVLLFPTMKPIDNNPNKEEE
                     N"
     gene            complement(2177..2656)
                     /gene="greA"
                     /locus_tag="KR231_002540"
     CDS             complement(2177..2656)
                     /gene="greA"
                     /locus_tag="KR231_002540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003514606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription elongation factor GreA"
                     /protein_id="HBH0004904.1"
                     /translation="MEENKEFLLTQEGYDKLEEELENLKVVKRKEVAERIKVAISFGD
                     LSENAEYDEAKKEQAQVEERILKLENMVRKAVIIDESKIDLNVVTIGSIVKVKDLEFD
                     EEVEYTIVGSTEADPYDGKISNESPVGKALLGRAAKEVVEVQVPDGVAKFEILEIRR"
     gene            complement(2765..3733)
                     /gene="dusB"
                     /locus_tag="KR231_002541"
     CDS             complement(2765..3733)
                     /gene="dusB"
                     /locus_tag="KR231_002541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA dihydrouridine synthase DusB"
                     /protein_id="HBH0004905.1"
                     /translation="MKIGNLELKNKVFLSPMAGVTDLPFRLICKEQGCGLLYTEMING
                     KALCYDDENTKKMLKIEEEEHPVAVQIFGSEPEFMGRAAEIMNDYSNEILDINMGCPA
                     PKVVKNGDGSALMKNPKLAEEVLRAVVKNSKKPVTLKIRKGWDDNSVNAVEIAKIAED
                     CGISALAIHGRTREQFYTGKADWDIIAEIKKNLSIPVIGNGDVFTIEDSINMLDKTGC
                     DAIMIGRGAQGNPWIFKRINHYMNTGEILPEPTLNEKISTAIKHLKLAVEEHGEYVAV
                     REMRKHIAWYLKGLRNSAKLRDEINKIEDYQEVVSKLEYYMEDSLT"
     gene            complement(3870..4640)
                     /locus_tag="KR231_002542"
     CDS             complement(3870..4640)
                     /locus_tag="KR231_002542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type III pantothenate kinase"
                     /protein_id="HBH0004906.1"
                     /translation="MLLVFDVGNTNMVLGIYKGDKLVNYWRIKTDREKTSDEYGILIS
                     NLFDYDNVNISDIDDVIISSVVPNVMHSLENFCIKYCKKQPLIVGPGIKTGLNIKYDN
                     PKQVGADRIVNAVAGIEKYGAPSILVDFGTATTFCAISEKGEYLGGTIAPGIKISSEA
                     LFQSASKLPRVELAKPGMTICKSTVSAMQSGIIYGYVGLVDKIISMMKKELNCDDVKV
                     IATGGLAKLIASETKSIDYVDGFLTLEGLRIIYEKNQE"
     gene            complement(4659..5249)
                     /locus_tag="KR231_002543"
     CDS             complement(4659..5249)
                     /locus_tag="KR231_002543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HBH0004907.1"
                     /translation="MMNTSASVRKVNVRKMTIIGVLSAISIMLSMTPLGFIPVGPTKA
                     TIMHIPVIIGAIMEGPIVGAAIGFIFGISSLLNAITNPTVTSFVFINPLVSILPRVMI
                     GVLAYYVYQLIIKATNKVYISGLITGAIGSLLNTAGVLGMIYVLYADKYLHAMGKSGS
                     AGKVIMALAAANGVPEAIVGALVVAAVATVLKKSKK"
     gene            complement(5433..6401)
                     /locus_tag="KR231_002544"
     CDS             complement(5433..6401)
                     /locus_tag="KR231_002544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="P1 family peptidase"
                     /protein_id="HBH0004908.1"
                     /translation="MYNNILDIEGLKVGQVEDRNGLTGCTVVICEEGATCGVDVRGSA
                     PGTRETDLLDPVNMVQKVHAVVLAGGSAYGLESTCGVSRYLEEKGIGFDVGVGKVPIV
                     VGAVLFDLGVGSFKCRPDLKMGYRACEVANTDILNQGNYGAGCGATVGKIRGQEYAMK
                     GGIGSYSIKLDNGLIVSALIAVNALGDVYENGKVIAGALNDKKTETIDTYKLMKQGES
                     KGGFSVDNTTIGIIATNAKLTKAGCKKISQMGHDGYAKSIFPIHTPHDGDTIFTISTG
                     EIEADITLVGSLAVEVVEKSIINAVKKADSVENIMAYKDIVKKREI"
     gene            complement(6394..7371)
                     /locus_tag="KR231_002545"
     CDS             complement(6394..7371)
                     /locus_tag="KR231_002545"
                     /EC_number="6.3.4.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin--[acetyl-CoA-carboxylase] ligase"
                     /protein_id="HBH0004909.1"
                     /translation="MRDKIIEIILNNKSEFISGEELSKQLGVSRAAIWKHMKALKEEG
                     YNIESVNKKGYRLAENPTDLLSPQNIYYKLDTEFIGKNIEHLDTIDSTNEHAKRIAIN
                     SVDGTVILSEHQDMGKGRLGRRWDSKPHEGIWMSIILKPDMEPFKAPFITLIAGASVT
                     KALNNLGANTLIKWPNDVILNGKKICGILTELSAEIERTNYVVLGIGINVKIMDFEQE
                     IADKATSLYKEGYMLSRVDIVRNVLTEFEKLYLDYTVNNSKEKTLKICRDYSAIIDKN
                     IYVLKGDNRELVKCLDINEEGNLLVQRSDGSIKEIISGEVSIRGEKGYV"
     gene            complement(7686..9656)
                     /gene="ftsH"
                     /locus_tag="KR231_002546"
     CDS             complement(7686..9656)
                     /gene="ftsH"
                     /locus_tag="KR231_002546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent zinc metalloprotease FtsH"
                     /protein_id="HBH0004910.1"
                     /translation="MNKLLKGAGFYLLVFIIIVGIVQFSGKPTEKIKDLKFSEVYREL
                     TDENISRLYFVNQTSVEGTIKDTNTKFKSYVPTEVMGNKLADEVLDQAKAGKLTFGGE
                     AKPSTPWFVEMLPTLLLIFFMVIIWFVFMNQSQGGGGKVMSFGKSKAKVHKDDEKTRV
                     TFKDVAGLDEEKEDLQEVVDFLKNPKKYIELGARIPKGMLMVGPPGTGKTYLSRAVAG
                     EAGVPFFSISGSDFVEMFVGVGASRVRDLFEQAKKSAPAIIFIDEIDAVGRKRGAGLG
                     GGHDEREQTLNQLLVEMDGFGVNQGIIIMAATNRPDILDPALLRPGRFDRQVVVGTPD
                     VKGREAIFKVHSRNKPLSDDVKMDVLARRTPGFTPADIENLMNEAAILTARKREKKIK
                     METIEEAITKVIAGVAKKSKVISEKERRLTAYHEGGHAVCAHVLEEVSPVHQVTIVPR
                     GRAGGFTMQLPVEDKFYATKNEMKENIVVLLGGRVAEELVLKDVSTGASNDLERVTAT
                     ARSMVTKYGMSSKLGPMSFDSDDEVFLGNSFSSKRNYSEEVAFEIDQETKRIVDGAYD
                     KTRSILQENMDRLEYVAQALLIYETLDAEQFVKAFNKELPLNEIENAVTEENSSKEVE
                     EQLTIKLEKDEEERNNVIDINKNLEDKSDKDK"
     gene            complement(9690..11078)
                     /gene="tilS"
                     /locus_tag="KR231_002547"
     CDS             complement(9690..11078)
                     /gene="tilS"
                     /locus_tag="KR231_002547"
                     /EC_number="6.3.4.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA lysidine(34) synthetase TilS"
                     /protein_id="HBH0004911.1"
                     /translation="MIFDKVLSTINKHNLIQKGDKIVLGLSGGPDSVCLLHVLNRLKK
                     DFNIEIYAAHLNHQIRGIEAQKDALYVSKLCEDMGIIFFVKSINVPKYCENEGLSLEE
                     GARKLRYEMFYEIKDKIKANKIAIGHNLNDQAETVMMRIMRGTGLKGLKGIDYIRDNC
                     IIRPILDVERNEIEEYCEAYNLNPRIDKTNLENIYTRNKIRLDLLPYMKDNFNSNVIE
                     SIVRMSNSLKSDNDYIEKEAEAKFREVSNIKEKGFVEINLDDFVCLHDAIKVRVLRNS
                     IKHILGDTNFVDQRHIEDIMSLEDNSKVNKMLTLPRNIFVYRKKDSIILTNEEIVNEE
                     IEFYYNVPSNGFIKIKELKQIIETQVMSIDRYKSMKLDNSSKGFDFNKVKGGIVIRSR
                     RQGDKIKLAMGSKKVKDLFIDLKIPREERCKIPIITDSEGIICVGDYKISENYKIDEN
                     TKEVLKINFNKL"
     gene            complement(11261..11689)
                     /locus_tag="KR231_002548"
     CDS             complement(11261..11689)
                     /locus_tag="KR231_002548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816442.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1934 domain-containing protein"
                     /protein_id="HBH0004912.1"
                     /translation="MEEKSLSVKISINTRQYDEKGNMDTIEMTAFGKIFYKNDGIYVI
                     YKEKEEDIEITNTIKILKNQVSIKKFGAINSTMLFKCGESSTTKYVTPQGTLLIDIDT
                     RELDINIQEGEHIKLKIDYNIKVQDLFLGRNKIDIYIGTK"
     gene            complement(11706..12512)
                     /locus_tag="KR231_002549"
     CDS             complement(11706..12512)
                     /locus_tag="KR231_002549"
                     /EC_number="5.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate racemase"
                     /protein_id="HBH0004913.1"
                     /translation="MNNKPIGVFDSGLGGLTVLKEIMKILPNEDIIYFGDTARIPYGS
                     RSKETIIKYTFQAINFLKTKGVKAIVIACNTATARSLKEAQEKYDIPIIGVIEAGART
                     AVSSTKNKIVGIIGTEGTISSKAYNLEISKIDESIEIVNKACPLFVPIVEEGWANTEV
                     AKLTAKIYLQELKEKNIDSLVLGCTHYPILKRTIGEEVGEHIKLVNPAKETAKDLKKI
                     LEVQNIINNTEIHGTYQYYVSDIPEKFSDIAREFLKKKIDKIQKVEIQKY"
     gene            complement(12714..13199)
                     /locus_tag="KR231_002550"
     CDS             complement(12714..13199)
                     /locus_tag="KR231_002550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall hydrolase"
                     /protein_id="HBH0004914.1"
                     /translation="MATLLALTFIFMPIKEVFAYEPTENIKKVNKQEKNIAKKEVINL
                     SDNDLMLLSKLVAGEARGESYEGQVAVAAVVINRVLDPRFPDTIEEVIYQKNAFSVVL
                     DGSIKMAPTDSARKAAQEALYGTDPTNKAVYFWNPEIATCKWINRLNPYMRIGNHVFA
                     K"
     gene            complement(13250..13909)
                     /gene="spoIIR"
                     /locus_tag="KR231_002551"
     CDS             complement(13250..13909)
                     /gene="spoIIR"
                     /locus_tag="KR231_002551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage II sporulation protein R"
                     /protein_id="HBH0004915.1"
                     /translation="MRKIKIRLGLLILSLISVISIMTIVINGEVKKVDNISKDYKDKL
                     IRFHVIANSNTDEDQELKLKVRDEVIKYLQPKLQNSKSIKESEAIIKKEYSSLEEISK
                     NIILKNGYNYSVKVGIQYSNFPTKQYSNIVLPAGEYKALKIIIGKGEGKNWWCVMFPP
                     LCFVDESNGVIDKSTDDKLKEVLTDKEYKLIKQDTPKKTSRVKIKFKVLEVVKDLEKK
                     F"
     gene            complement(14054..14734)
                     /locus_tag="KR231_002552"
     CDS             complement(14054..14734)
                     /locus_tag="KR231_002552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBH0004916.1"
                     /translation="MENLTKLNLDNYKPLRDVVFENLREAILEGKLKPGQRLMEVQLA
                     EQLGVSRTPVREAIRKLELEGLVVMLPRKGAYVANMSLKDIMDVLEVRASLEGLAAYL
                     AAERISDEDIKKLKDISEEFKKSTLESDVDALLKLDVEFHECIFKATNNKKLIQLINS
                     LWEQVYRFRVTYMSAYDTSHNIVEEHKYLLDAIIKGDSELSKKYATEHIEKAEQFMID
                     KAMISKDL"
     gene            complement(14718..15608)
                     /locus_tag="KR231_002553"
     CDS             complement(14718..15608)
                     /locus_tag="KR231_002553"
                     /EC_number="2.7.1.148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-(cytidine
                     5'-diphospho)-2-C-methyl-D-erythritol kinase"
                     /protein_id="HBH0004917.1"
                     /translation="MDFIRLKSRAKINLSIDVLGKRQDGYHFVEMIMQTIDLYDIVKI
                     KELDEDEIKVKSTSLDIPLDEDNIVYKAAKILKNKFYIKKGVEIFIEKNIPVAAGMAG
                     GSSNAAAVLVGLNHLWELRLSEDELKEIGLNLGADVPFCISGRPALAQGIGEKLTNIK
                     GLPCDTNILICKPDLFVSTKEVYQGLDLNNIKKRPNNKYLIECLKSEDIKAVSESMVN
                     ILENVTIGKHKEISDIKQVMMKNNALGSMMSGSGPTVFGLFKNKEDALIGKKELLKKY
                     KQVYVVNSSQKGVEICGEFN"
     gene            complement(15726..17276)
                     /locus_tag="KR231_002554"
     CDS             complement(15726..17276)
                     /locus_tag="KR231_002554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3794 domain-containing protein"
                     /protein_id="HBH0004918.1"
                     /translation="MELIKDVIKVDNRIDFGKFQTFIEAEAVVPDKKLDVYEIVKTEG
                     YISLKKIEMADGKILCRGSFNYNVIYIADDKNTISNVDGKVDINEVIEKDNVVQDMEY
                     MLFSEVEHMDCTIMNERKIKVGALMNIRGSLFEKQRLDIVKDVAQVEGIQKHRKEICF
                     QDIVGIEKAESSIRDTITINTEEIQSIISLNPCVKVKESRVTDNKVIIGGVLEINPLA
                     CTYEGELVELDRVGIEFTQFVEVPGVSDGMTEEVLLSMSDFNHIFKQNSESNTGLLEI
                     DCMACCKVKVTDEVTREVLQDAYSPQKIIKFDHKPIQLNKTLRRSEETFMVREGIRND
                     NDDIQIKDIVSVCPTMSIENSYIEGNKSIIQGIIKVEILFVPVEGLKLVYKISEEIPF
                     EHDIEMDNLTDTASVFNTACIDKVEVDLNRDQIDLIIKIKRFTEALDKKAENFIIKGE
                     DQGVYDLSKAPSIIVYICKEGDTFWNIAKKYNTTENEIAELNDIKLDEPIKPGKCLIL
                     EKKVVLVD"
     gene            complement(17370..17636)
                     /locus_tag="KR231_002555"
     CDS             complement(17370..17636)
                     /locus_tag="KR231_002555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Veg family protein"
                     /protein_id="HBH0004919.1"
                     /translation="MATVQTLDKIRVSLERHIGKKILLKANKGRKQIITKEGILEKVY
                     PSVFVIKLDDESNGYPRVSYSYSDLLTSNVKLQVFRDQDKLQIS"
     gene            complement(17784..18644)
                     /gene="yabG"
                     /locus_tag="KR231_002556"
     CDS             complement(17784..18644)
                     /gene="yabG"
                     /locus_tag="KR231_002556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422239.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sporulation peptidase YabG"
                     /protein_id="HBH0004920.1"
                     /translation="MKVGDIVARKSHNKDIVFKIVSFGVDENNEKIAILKGIAFRVIA
                     DAYIDDLELVKAPDIKDILIDKNVENLLYKSVRKAKERQKRMTRAVPKLQLNPNTYGM
                     PGKVLQIDGDKEYLKICLDVYAQLGIPAVGVAVSEQNQYKEVRALLEKYNPDILVITG
                     HDAMTIKRGDIEDMSNYRNSSNFVKTVKEARKWQPNLDNLVIFAGACQSNYEKIISAG
                     ANYASSPGRIMIHALDPVFIVEKIACSRIDVVVPIDEVIEQTITGVKGIGGSETRGKF
                     RWAMPKTILH"
     gene            complement(18728..19666)
                     /locus_tag="KR231_002557"
     CDS             complement(18728..19666)
                     /locus_tag="KR231_002557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptidase"
                     /protein_id="HBH0004921.1"
                     /translation="MKFIDLHCDTIAKLMENVETSELKSNKYSVDIDRLKKGDSLAQT
                     FALFVDTEEVKHPFDYCMSMANKFHEEMKKNSDEIALATNYEEIMKNQSEGKLTALLS
                     IEEGAVLEGKLENLKKFYDLGVRMMTISWNHVNELSFPHNKVEYREKGLTDFGREVVH
                     KMNELGMLVDVSHISDGGFYEIAKISSKPIIATHSNSRAMMNHSRNLTDDMIKVLANK
                     GGVTGINFFHLFLSDKSESKLEDMVRHIKHIVNVGGIDVVSLGSDFDGIDSKVEIEDI
                     SQMGKLYEPLKKEGFSEDDIEKIYYKNALRVIKEVL"
     gene            complement(19776..19937)
                     /locus_tag="KR231_002558"
     CDS             complement(19776..19937)
                     /locus_tag="KR231_002558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0004922.1"
                     /translation="MFILRFADDDDNLSVKDFTSLTDLKKYISENNIDKTWHQIEEVK
                     KVIPNLKEE"
     gene            complement(19947..20444)
                     /locus_tag="KR231_002559"
     CDS             complement(19947..20444)
                     /locus_tag="KR231_002559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SEC-C domain-containing protein"
                     /protein_id="HBH0004923.1"
                     /translation="MSLYTEWRNLSDNHESQEAEVKFWEEYLKVEAGIYNEILNNKMD
                     VVEGKVSELAEKFGTTNEFFMGFIDGISESLKEDIVLEEVEADKEVSIKIDWEKLYNN
                     MVTVEAHWLYNLQGWEDILPADQRKEIIKAYKKSKTIVKEAKIGRNDSCPCGSGKKYK
                     KCCGK"
     gene            complement(20559..21269)
                     /locus_tag="KR231_002560"
     CDS             complement(20559..21269)
                     /locus_tag="KR231_002560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UPF0489 family protein"
                     /protein_id="HBH0004924.1"
                     /translation="MENYEYSGFYIEKPVGNNVFSYDKRENKSIYVPKLINGTLNDVR
                     LGNEVVFNEVDENKEIKAKGLENMVEYVLGNKKIYVFDNHNHAFYFWAKSLLKGEFTK
                     GCKLVHVDQHKDTREPENYDVDVNNLKDVFRYTNEVLNVGSFIKPALKYNIFSELIII
                     DSLYGFDLEVESEFVLDIDLDIFSSDMDYIPFELKFYKIKNLIKKAKVITIATSPYFI
                     NQEYAIKVLKELFNYDII"
     gene            complement(21445..21975)
                     /locus_tag="KR231_002561"
     CDS             complement(21445..21975)
                     /locus_tag="KR231_002561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0004925.1"
                     /translation="MDIRALPIRITKEEAIEIAKSGKNSLFSKLILKNKYAHEVRLHY
                     IEFKIITLKIHKTKSIFKNRRYSNDINELKILVNGSTGSGSIVQDFPTYEVVKNVDCN
                     IVQYSDKDERRVKAKANKMAMRLTHRFMGGIPEIEIVKIESIFRPYWVVFFGKVELNR
                     RVSYLPIEADGFVIGM"
     gene            complement(21992..22222)
                     /locus_tag="KR231_002562"
     CDS             complement(21992..22222)
                     /locus_tag="KR231_002562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0004926.1"
                     /translation="MSKLVSKVKKDLEIKWLGIDGFLVLLYFLITGFIFYGILTRNDI
                     IVGKIIPYGVMSVVIVIFFDYIYRVLKMTRKK"
     gene            complement(22237..23631)
                     /locus_tag="KR231_002563"
     CDS             complement(22237..23631)
                     /locus_tag="KR231_002563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:solute symporter family protein"
                     /protein_id="HBH0004927.1"
                     /translation="MLTFWENGIIVIFAFILLGIGYYFSRNVKDMESYYLGNRSLPWS
                     LIVGTLVASWYGGVGTVGSVEYAAIYGISAWAVWSIAAHIGRMPLALWVGPRIHIRTN
                     ITVPDLLESFYGKHVAIIGAILMFIYCAQLGEITAMGTIGNVAWKIDKELIGLIMVGV
                     VVVLTVLGGLMGVAITDMVLFFCMVFGLTMVMPGQFEQIGGFQGLTEALKDAPQLMHP
                     TKGMSAMKALMLIVYSFGAYSDPTFYQRFSAADSPKVGRRALLTCFSLWICFDMVLTM
                     TGLIVRATYPEMAPAAGYITLVLDTLPQGIRVIFIIGILGSIISTLDSYYLAAGATLA
                     NDIYGRITKKELSQKQLVKFTRIGVCLAAVMGLSVAFRFENVYDACIFVGSIWMGSAF
                     VPIVGGLLGNGRRTSMGGILGMIVGGVTFGYFKIFPVQSFELEPLVIAIPFSFIAWMI
                     GNRIGENLNTQNNL"
     gene            complement(23757..25010)
                     /locus_tag="KR231_002564"
     CDS             complement(23757..25010)
                     /locus_tag="KR231_002564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBH0004928.1"
                     /translation="MESKNNVKRFLIIFILAFGTTAMYSLPYMKSSFYDPMQQALALS
                     HTQIGNLLSLYGLVGMVSYFIGGWFADRFSVRKLITFSLIASGILGFYFSTFPSYSMI
                     LLIFVLWGFTTILTFFSASVKVVRMQGSESEQGRIFGFYEGLSGVSGTLISFIGLYFF
                     GKFAEITVGFKYVVWLYSAASIICGILLFFLVEEKKDSGASDEGLSIKSLLKVVTMPK
                     AWLIGLIIFSTYLVFSSLTYLSPYLSEVYVMPMTLVSALSIIRTYVIKMGASPVAGVI
                     TDKVGSSIRVMFVGFILMTVSTAAYLVIPKSTGFIWIAVINMIILSVILFGFRGIYFA
                     SVSESNISLETTGAVVGFASFIGFSPDAFYYTIAGNWLDKYGQTGYTYIFILSVVCAV
                     IGIFATYALNKINKRENKGLNNKIA"
     gene            complement(25061..26215)
                     /locus_tag="KR231_002565"
     CDS             complement(25061..26215)
                     /locus_tag="KR231_002565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class I/II-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="HBH0004929.1"
                     /translation="MSNNINQDLETKIIHWGHSADPTTGALATPICQTATFAAKTVEH
                     FEELCMTWGYVYTRECNPTLTELEAKLAMLENAESAISSTSGMGAITSTILALVKSGD
                     HIVSSDGIFSHTKLFMSELLSKFGVEVTFVDAVNPQNVKEAMRPNTKIVYIESPLNPS
                     LDLVDIKTIAEIAHENKSLAIVDSTFGTPIVQRPIDLGADLVIHSLTKFINGHGDTLG
                     GAVAGSKELIDLVRWPSLCCFTGASLPPMSAWMILRGMKTLDMRMKKHCENGLAVAEF
                     LEEEENVELVKYPALKSHPQYELCKTQMNGLGGGVVSFKLKDGINGLTRDQASRRLMN
                     SLELATIATSLGEEHTLVQMNGENLIRIAVGLESSNDIINDFKQAIEKLK"
     gene            complement(26775..27344)
                     /locus_tag="KR231_002566"
     CDS             complement(26775..27344)
                     /locus_tag="KR231_002566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HBH0004930.1"
                     /translation="MIIIYGYCRVSTKNQTDNNSLYQQQQEILNKYNDAKIIKETYTG
                     TTTNRPKFEKIISSLKKGDLLVATKLDRLARSTSEGIQLIEGLFAKEVSVHILNIGLL
                     ENTSMGKFFLTTLLAVAELERNMIIERTQLGKEFAKKKKDFKDGRPKKYSNQQIQYAL
                     GLLNSKPYREVVKMTGISKSTLIRAKKSI"
     gene            27547..27774
                     /locus_tag="KR231_002567"
     CDS             27547..27774
                     /locus_tag="KR231_002567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HBH0004931.1"
                     /translation="MNSLLKEAIDELKNIHCGEVFLLKELFKGYEWNRLEMNIRLKLG
                     KLFLYEVVTNPNLNVEVINKNSAYQQMYKKK"
BASE COUNT         8571 a         5307 c         2776 g        11149 t
ORIGIN      
        1 tttcgtcaat actttttttg ttttttattt taaaaaaggt tataactttt gtttttttta
       61 ataaatataa ttaaaactaa tagatataac ccttgatatt acaaacaata catgcatata
      121 taattttacc tattttgcaa ttttattttc ataagaatat gaattagctc tcactctatc
      181 tgcccaaaca tttatactct taactttatt aacattagtt gtaccctcaa aaatatccat
      241 tgcatcctta caaaaatata tcataacatc aagaaccaaa aatccaacac aaaataaaca
      301 taaaaaatta attacttgaa acatcagaca ttcccccaat aattttttat atatagtatt
      361 ctcataaatt attcttttta ccttctcata aattattcta aatattttca taataaatta
      421 ctttcaatca tattttctaa atataaagtc tcaatcaaca aaaactaata tcaatttcta
      481 acgtttgttg gtaatttata aattaaatat ctaaaagaat ctttgaagca tataaaaagc
      541 attctacact gacattttaa ataaaattta gctatttatt gataatttaa tagctaaact
      601 ttatttaaaa cttagtagaa tgctaatatt tcttagtttt cttcttcttt atttggattg
      661 ttatcaatag gtttcatagt cgggaataat aatacatctc ttatagatgg agagttagtt
      721 aataacataa ttactctatc tatacctatt cctagtcctc ctgtaggagg tagacctacc
      781 tctaatgctt ttaagaaatc ttcatccatt tcaaaagctt catcatcacc taattctctt
      841 tttcttaatt ggtctataaa tcttcctttt tggtcaatag ggtcattaag ttcagaaaat
      901 gcattagcta actcccactt attagcaaat gcctcaaatc tatcagttct tcttgggtct
      961 tcaacatttc tcttagataa tggagatact tcaactggat gatgagttat aaatgttggt
     1021 tggattaatt tatcttctcc aaattcttca aagaaagcat ttattacttc tcctcttctc
     1081 attccaggtt ttatctctat acctttttct ctagcaactt ctagtgcctc ttcatctgta
     1141 tttatagtag aaaaatctac accagaatat tctttaacac aatcttccat actcattctt
     1201 ttccaaggtg gtgtaaagtt tatttctgtt ccttgatagt taactatcat acttcctgta
     1261 gcaacttcag ccatatgtgc aataacattt tctgttattt ccatcatatc agtatagtct
     1321 gcatatgctt gatataattc tattgcagta tattcaggat tatgttttaa atccatacct
     1381 tcatttctaa acattcttcc catttcataa actttatcaa atccaccaac aataagtctt
     1441 tttaaataca attcattcgc tattcttaaa tacattggta tatgtaaagt attatgatta
     1501 gttataaatg gtctagcatt tgccccacct gctatagtat ttaatattgg agtctcaact
     1561 tctaaaaatc ctctatcatc taagtatgct cttaatgctt ttaatgcttt tgttctaatt
     1621 aaaaaagcat tttttacttc tggatttact attaagtcaa catatctttg tctatatctt
     1681 agttcttggt cttttaatcc atgatatttt tctggtaaaa cttgtaaaga tttacatagt
     1741 aatactacag atttagcctt tacagatatt tcaccttttt tagttttaaa gatttctcct
     1801 tcaattccaa ctatatctcc aatatcatat gttgaaaata cactatattc ttcctctcct
     1861 atagcatcta gtcttacata agattggatt cttccctctt ggtcttgaat atctataaag
     1921 ccagctttcc cttgtattct cttgctcatt atacgtcctg ctatttttgt agttttaccc
     1981 tcaagagaat caaagttatc ttttatatcc atagaataat gagttctatc atatctactt
     2041 tctttaaaag gatctctacc tgattcttgt aattttttta gtttatctct tcttacttga
     2101 agtacttcac taaggtcttc ttgaatttgc gcttcttcat tgctttgttg attatttttc
     2161 atttttttcc tccaaattat cttcttattt ctaatatttc aaacttagca actccatcag
     2221 gaacttgcac ttccacaact tctttcgcag ctctacctaa aagtgctttc cctacaggag
     2281 attcgtttga tattttacca tcatatgggt ctgcttctgt cgaaccaact atagtatatt
     2341 caacctcttc atcaaattct aaatccttaa ctttaactat tgatcctatt gtaacaacat
     2401 taaggtctat tttgctttca tctatgataa cagcttttct aaccatattt tctaatttta
     2461 aaattctttc ttcaacttgt gcttgttcct ttttagcttc atcatactca gcattttcag
     2521 ataaatcacc aaaagatata gcaactttta ttctctctgc aacttctttt ctctttacaa
     2581 cctttaagtt ttctaattct tcttctaatt tatcatatcc ctcttgtgtc aataaaaact
     2641 ctttattttc ttccattata aatacaactc cttcacaaat ttcttaggaa ttttcctaat
     2701 tatattttaa aaattttata atcttttttt aatttatgcg ctatattata agtcactatt
     2761 atttttatgt caaggagtct tccatatagt actccaattt cgacacaact tcttgatagt
     2821 cttctatttt gttaatttca tcccttaatt ttgcagagtt tctaagtcct tttaaatacc
     2881 aagcgatgtg ttttctcatt tcccttacag ctacatactc tccatgttct tctactgcaa
     2941 gttttaaatg cttaatggca gtacttattt tttcgttaag agttggctct ggcaaaatct
     3001 cgcctgtatt catataatgg tttattcttt taaatatcca agggttacct tgagcacccc
     3061 tacctatcat tatagcatca caaccagttt tgtctaacat atttattgaa tcttctattg
     3121 taaatacatc accatttcct ataacaggta tactcaaatt tttcttaatc tctgcaatta
     3181 tatcccagtc tgctttgcct gtataaaact gttctctagt tcttccatgt attgctaaag
     3241 cacttattcc acaatcctct gctatctttg ctatttcaac agcatttaca ctattatcat
     3301 cccagccttt tcgaatcttt aaagtcactg gcttttttga gttcttcact actgccctca
     3361 atacctcttc tgcaagctta ggatttttca taagtgctga accatctcca tttttaacta
     3421 cttttggagc tggacacccc atatttatat cgagaatctc atttgaataa tcattcatta
     3481 tctctgctgc tcttcccata aactctggtt ctgaaccgaa tatctgaact gctacaggat
     3541 gttcttcctc ttctatctta agcatttttt tagtattttc atcatcatag caaagtgcct
     3601 taccatttat catttctgta tataaaagcc cacatccttg ttctttacaa attaatctaa
     3661 atggaaggtc tgttacacct gccataggtg atagaaaaac tttatttttc aattctaaat
     3721 ttcctatttt cattgttttt ctcctatttt tgcctttatt ttgtgattta actttaaatt
     3781 cttatttcct cattataata taccacatat agctagaaat ctatcataaa aagggaattg
     3841 gatatataac ccaattccct gtatattaat tattcttggt ttttttcata tattattctc
     3901 aatccttcta gtgttaaaaa accatctaca taatctatac ttttcgtctc tgaagcaatc
     3961 agtttagcta acccacctgt agctataacc ttaacatcat cacaattcaa ttctttcttc
     4021 atcatactta ttattttgtc aactaaacca acatatccat aaattattcc agattgcatg
     4081 gctgatacag tactcttaca aatagtcata cctggcttag ctaattctac tctaggtaat
     4141 ttagacgcac tttgaaataa cgcctcacta gatattttta ttcctggtgc tattgttcca
     4201 cccaaatatt cacctttttc agagatagca caaaatgtag ttgctgttcc aaaatcaaca
     4261 agtatacttg gtgctccata cttttctatc cctgctacag cattaactat tctatctgcc
     4321 ccaacttgtt ttggattatc atattttata tttagacctg tttttatgcc tggacctact
     4381 attaatggct gttttttaca gtactttata caaaagtttt caagagaatg cataacattc
     4441 ggaactacag atgatattat aacatcatca atatcactta tattcacatt atcataatca
     4501 aataggttac ttattaggat tccatattca tcagacgttt tttctctatc tgttttaatt
     4561 ctccagtaat taactaattt gtcaccttta tatataccta aaaccatatt agtatttcca
     4621 acatcaaata ctagaagcat atgtcattaa ccttctttct attttttgct tttcttaagt
     4681 acagtggcaa cagcagctac tactaaagcc cctactattg cttctggcac cccatttgct
     4741 gcggcaagag ccattattac ttttcctgct gaaccacttt tacccattgc atgaagatac
     4801 ttgtcagcat ataagacata tatcattcct aaaactccag ctgtatttaa cagagaacct
     4861 attgcccctg taattaaacc tgatatgtat accttatttg tagccttaat tattaactga
     4921 tatacataat aagctaatac acctatcata actcttggta atattgaaac taatggattt
     4981 ataaaaacaa aagatgttac tgttgggttt gttatagcat ttaagagact tgatatccca
     5041 aatataaatc ctattgctgc cccaactatt ggtccttcca taatagctcc aataataact
     5101 ggtatgtgca ttatagttgc ttttgtaggt ccaactggaa taaatcccaa tggagtcata
     5161 gatagcataa tagaaatagc tgatagtact cctattatag tcatctttct tacatttact
     5221 tttcttactg atgcacttgt gttcatcata aaaaatacac ctccgttcca gctcattaag
     5281 atgccggact acttaatttt ttaatttttt tcgttttttt cttataacta tgagtcaagc
     5341 taccattgta ggatgcccgc tctaacaaga ataattttat caagatgagt tgccattgtc
     5401 aacaatttga caagaaaaat atgctaattt catcatattt ctcgtttttt tactatatct
     5461 ttatatgcca ttatattttc tacactatcc gcttttttta ctgcatttat tatacttttt
     5521 tccacaacct ctacagccaa tgaacctact aatgttatat ctgcttctat ttctcctgtt
     5581 gatattgtga atattgtatc tccatcatga ggtgtatgga taggaaaaat agacttagca
     5641 tatccatcat gtcccatttg agatatcttt ttacatccag ctttggttaa cttagcattt
     5701 gttgcaatta tcccaattgt agtattatct acactaaatc cacctttact ttcaccttgt
     5761 ttcattaatt tatatgtatc aattgtttct gtctttttat catttaaagc accagctata
     5821 accttaccat tttcataaac atctccaaga gcatttacag caattaatgc agatacaatt
     5881 agaccattat ctaattttat agaatagcta cctattccgc ctttcatagc atattcctga
     5941 cctcttatct ttccaacagt ggctccacaa cctgctccat aatttccttg atttaaaata
     6001 tcagtatttg caacttcaca agctctataa cccatcttta aatctggtct acatttaaag
     6061 ctccctactc ctaaatcaaa taaaactgct cctacaacta taggcacttt acctacacct
     6121 acatcaaatc caattccttt ttcttctaag tatctactta caccacaagt ggattcaaga
     6181 ccatatgcag aacctccagc caaaactact gcatgaactt tttgaaccat atttacaggg
     6241 tctaataaat cggtttctct agtacctgga gcagagcccc ttacatcaac accgcaagta
     6301 gctccttctt cacatattac tactgtgcac ccagtaagac catttctatc ctcaacctgc
     6361 ccaaccttta agccttctat atccaaaata ttattataca tatccttttt ctcctcttat
     6421 agaaacttca cctgaaataa tttcttttat acttccatca cttctttgaa ctaataaatt
     6481 tccctcttca tttatgtcta aacatttcac tagttctcta ttatctcctt ttaatacata
     6541 tatattttta tctataattg cagaataatc tctacatatt tttaaggttt tttctttgga
     6601 attatttaca gtataatcta aatataattt ttcaaattca gtcaatacat tcctaacaat
     6661 atctactctg gataacatat acccttcttt atacaatgat gtggctttgt cagctatttc
     6721 ttgttcaaaa tccattattt taacatttat tccaattcca agaacaacat aatttgttct
     6781 ttcaatttca gcagataact ctgttaatat accacatatt ttttttccat ttaaaataac
     6841 atcatttggc cattttatta atgtatttgc tcctagattg tttaaagctt tcgttacact
     6901 tgctcctgct attaaagtta taaatggggc tttgaatggt tccatatctg gttttaatat
     6961 aatactcatc cagattcctt catgaggttt tgaatcccat cttcttccca atcgtccttt
     7021 ccccatatct tgatgttcac ttaaaatcac agtcccatct acactattta tagctatcct
     7081 tttagcatgt tcatttgttg aatctatagt gtcaagatgt tcaatatttt ttccaataaa
     7141 ctctgtatct aatttatagt aaatattctg tgggcttaat aaatcagttg gattttccgc
     7201 taatcgatac ccttttttat ttacagattc tatattatat ccctcttctt ttaaggcttt
     7261 catatgtttc catatagctg cacgtgacac ccctaattgt tttgataatt cttctcctga
     7321 aataaattca gatttattat ttaatataat ctctattatt ttatctctca tatttcacct
     7381 ctaatatgac ataatttcat gacttatttt cttctaataa ataattatac attattaata
     7441 tacttttaat actattaatt ttaaatttcc tttttaatta ttataatggt tgttttatat
     7501 tttatattga tgatttatat aattttacat tttatttaaa taattttaaa ataataaaaa
     7561 aactgaaagt atcaattaaa ttaatacatg caaatataat ttgcttatta atttaatatt
     7621 atactttcag ttttagtatt taatccacat cagataataa tcttaaaatg accaaggtct
     7681 taaaactatt tatctttatc agatttatct tctaaatttt tatttatatc aataacattg
     7741 tttctttctt cttcatcttt ttctaatttt atagttaatt gttcttcaac ttctttagaa
     7801 gaattttcct ctgtaactgc attttcaatt tcattcagag gtaactcttt attaaatgct
     7861 tttacaaatt gttctgcatc taaagtttca tatataagta aagcttgtgc tacatactct
     7921 aatctatcca tattttcttg taatatactt cttgtcttat catatgcacc atcaactata
     7981 cgctttgttt cttggtctat ctcaaaagca acttcttcag aataatttct cttacttgaa
     8041 aaactattac ctaggaatac ttcatcatca ctgtcaaatg acattggacc aagtttagaa
     8101 ctcattccat actttgttac catacttctt gcagtagctg taactctttc taagtcattt
     8161 gaagcacctg tagatacatc cttaagtact agctcttctg ctactctacc accaagtaaa
     8221 actacaatat tttctttcat ttcatttttt gtagcataga acttatcttc aacaggaagt
     8281 tgcattgtaa accctccagc tcttcctctt ggaactattg taacttgatg aacaggactt
     8341 acttcttcaa gtacatgggc acaaactgca tgccctcctt catggtatgc tgtaagtctt
     8401 ctttctttct cacttattac tttcgatttt ttagccacac ctgctataac ctttgttata
     8461 gcttcttcta tagtttccat cttaattttc ttttctcttt ttctagctgt taatattgca
     8521 gcctcattca ttaagttctc tatatcagca ggagtaaatc ctggtgttct tctagccaag
     8581 acatccattt ttacatcatc acttaatggt ttatttcttg agtgaacttt aaatatagcc
     8641 tctctacctt ttacatctgg tgtaccaaca acaacttgtc tgtcaaatct tcctggtcta
     8701 agtaaagctg ggtcaagtat atctggtcta tttgtagctg ccatgattat tataccttga
     8761 tttaccccaa atccatccat ttcaactaga agttgattaa gagtttgctc tctttcatca
     8821 tgacctccac caagacctgc acctcttttt ctaccaactg catcaatttc atctatgaat
     8881 atgatagctg gagcactttt cttagcctgt tcaaataaat ctcttactct tgaagcacca
     8941 accccaacaa acatctcaac gaaatcagaa ccacttatac tgaaaaaggg aactcctgct
     9001 tctcctgcaa ctgctcttga tagatatgtt ttaccagttc caggaggtcc taccataagc
     9061 attccttttg gtattcttgc acccaattca atatatttct taggattctt taagaaatct
     9121 actacctcct gcaaatcttc tttttcctca tctagtccag ctacatcttt aaatgtaact
     9181 ctagtttttt catcatcttt atgaacctta gcttttgatt tgccaaaact cataaccttt
     9241 ccgcctccac cttgagactg attcataaac acgaaccaaa taatcaccat gaagaatatt
     9301 aacagtaatg taggcaacat ttcgacaaac caaggtgtag atggcttagc ttcaccacca
     9361 aaagttagtt tcccagcctt agcttggtct aacacctcat ctgcaagttt atttcccatc
     9421 acttctgttg gaacatatga cttaaacttt gtatttgtat cttttatagt accttctaca
     9481 gaagtttgat ttacaaagta taatcttgat atattctcat ctgttaattc tctatatact
     9541 tcagagaatt ttaaatcttt tattttttct gtaggcttac ctgagaattg aactatacct
     9601 actataatta taaaaacaag tagataaaaa cctgcccctt ttagcaactt attcaatata
     9661 gaagccctcc tttcatacat tgctttgccc tataatttgt taaaattaat ttttaatact
     9721 tcttttgtgt tttcatcaat tttataattt tcactgattt tataatctcc aacacatatt
     9781 attccttcac tatctgtgat tataggaatt ttacatcttt cttctcttgg gatttttaaa
     9841 tctatgaata aatctttcac ttttttactt cccatagcaa gctttatctt atcaccttgc
     9901 cttctgcttc ttattactat accccctttt accttattaa aatcaaaccc tttagatgaa
     9961 ttgtctaatt tcatactctt atacctatct atgctcatta cttgggtctc aataatttgt
    10021 tttaattctt ttattttaat aaacccatta ctaggtacat tgtaataaaa ttcaatttcc
    10081 tcattaacaa tttcctcatt cgttaatatt atactgtctt tttttctata aacaaatata
    10141 tttcttggaa gagttaacat tttatttact tttgaattat cttctaaaga cattatatct
    10201 tctatatgtc tttggtcaac aaaattagta tctcctagta tatgttttat ggaatttcta
    10261 agaactctaa ctttgatagc atcatgtaag caaacaaaat cgtctaaatt tatctctaca
    10321 aagccttttt cttttatatt tgaaacttct ctaaatttag cttctgcctc tttctcaata
    10381 taatcgttat cactttttaa actattgctc atcctcacta tagattctat tacatttgaa
    10441 ttaaaattat ccttcatata tggtaaaagg tctaacctta tcttatttct agtgtatata
    10501 ttttctaaat ttgttttatc tatcctcgga tttaaattat aagcttcaca atactcctct
    10561 atctcatttc tttccacgtc taatatgggt ctaattatgc aattatctct aatataatca
    10621 attcccttta agccttttaa acctgttcct ctcatgatac gcatcataac cgtttcggct
    10681 tggtcattga gattatgacc tattgctatt ttattggctt taatcttatc cttaatttca
    10741 taaaacattt catatcttag cttccttgct ccttcttcta atgataatcc ctcattttca
    10801 caatattttg gtacattaat agactttaca aagaatataa ttcccatatc ctcacaaagt
    10861 ttagatacat ataatgcatc tttttgagct tctatccctc ttatttgatg gtttaaatgt
    10921 gctgcatata tttctatatt aaaatctttt tttaatctat ttagtacatg caataaacaa
    10981 actgaatcag gtcctccaga aagacctaaa actattttat cgcctttttg tattaaatta
    11041 tgtttattta tagtacttag taccttatca aatatcatat ttatccctct tacacttagt
    11101 tttattcact tttaagtata ctttctataa aaaaacgcta aacccttgta tcaattttaa
    11161 gaaattaaag tttaatataa atataataat accaaataaa ttaaataaaa ggtagttttt
    11221 tcactacctt tataaaattt ctggaaaata gccatagtta ttatttagta cctatgtata
    11281 tatctatttt attcctacct aaaaataaat cttgtacctt tatattatag tctattttca
    11341 attttatgtg ttccccttct tgtatattta tatctaattc tcttgtatca atatcaatta
    11401 ataaagtacc ttgtggggtc acatactttg tagtactact ttctccacat ttaaacagca
    11461 ttgttgagtt aatagcacca aactttttga tactaacttg atttttaagt atctttatag
    11521 tattagttat ttctatatct tcttcttttt ccttgtaaat aacatatatt ccatcatttt
    11581 tataaaaaat tttaccaaag gcagtcatct ctatggtgtc catatttcct ttttcatcat
    11641 attgtctagt atttatactt atttttacac tcaacgattt ttcctccata gattcttcat
    11701 ataaactagt atttttgtat ttctactttt tgaatcttat caattttttt ctttaagaac
    11761 tctcttgcta tatctgaaaa tttttcaggt atatctgata cataatattg ataagttcca
    11821 tgaatttctg tattgtttat aatattttgc acctctaaaa tcttttttaa atcctttgca
    11881 gtctctttag ctggattaac aagttttata tgctctccaa cttcttcacc tattgttctc
    11941 tttaaaatag gataatgagt acatcctaac actaaagaat ctatattttt ttctttcaat
    12001 tcttgtaaat atatctttgc tgtcagttta gccacttctg tatttgccca tccttcttca
    12061 acaataggca caaataaagg acatgcttta ttaacaattt ctatactctc atctatttta
    12121 gatatttcca agttgtatgc ttttgaactt atagttcctt cagttcctat tattcctaca
    12181 attttgtttt ttgtagaact tacagctgtt ctagctcctg cttctataac tccaattatc
    12241 ggtatatcat atttttcttg agcttctttt aagcttcttg cagtagcagt gttacatgct
    12301 ataactatag cttttacacc ttttgttttt aaaaagttta tagcttgaaa agtatattta
    12361 attatagttt ctttggatct tgaaccatat ggtattctgg cagtatctcc aaagtatatt
    12421 atatcctcat ttggtaatat cttcattatc tcttttagaa ctgttaatcc acctaatccc
    12481 gaatcaaaaa ctcctattgg tttattgttc atctttatac aacacctact ttacattttt
    12541 gtgtttaaca acaacttatt tatcgctaaa atttatattt atattcataa ttaatatatt
    12601 attacctaaa tgattattat agtttatttt acacaaaaaa taaaggagct atcttaaatt
    12661 agaaaataat ttctacaaaa agacaactcc tttcactact taaaaattta aatttatttt
    12721 gcaaacacat gatttcctat tctcatataa ggattcaatc tatttatcca tttgcaagtg
    12781 gctatttctg gattccaaaa atatactgct ttattagttg ggtcagttcc ataaagagct
    12841 tcctgagctg ctttacgtgc tgagtctgtt ggtgccatct ttattgaacc atcaagcaca
    12901 actgagaaag catttttttg atatatgact tcttctattg tgtctggaaa tctagggtcc
    12961 aatactctat ttattactac agctgctaca gcaacctgtc cctcatagct ttctcctcta
    13021 gcttctcctg caaccaactt agataataac atcaagtcat tatcagataa atttattact
    13081 tctttctttg ctatattttt ttcttgtttg tttactttct taatattttc tgttggttca
    13141 tatgcaaata cctctttaat aggcataaat ataaaagtca aagctaatag tgtagccatc
    13201 agtttactcc acctgtccat gattaaaacc actccttaca ttcttatttt taaaattttt
    13261 tctctaaatc cttgactact tcaagtactt taaatttaat ttttactcta cttgtttttt
    13321 ttggtgtatc ttgttttatt aacttatatt ctttatcagt taaaacttcc ttcaacttat
    13381 catctgtaga tttatctatc actccattag attcatcaac aaaacatagt ggagggaaca
    13441 taacacacca ccagtttttt ccttcacctt tcccaatgat aatctttaat gctttatatt
    13501 caccagctgg aagaactata ttagaatatt gtttagtagg gaaattgcta tattgtatac
    13561 ctacctttac actgtaatta tatccatttt taagaataat atttttactt atttcttcca
    13621 aactactata ttcctttttt ataatagctt cactttcttt tatacttttt gaattttgaa
    13681 gctttggctg taaatatttt attacttcat ctctaacttt tagtttaagt tcttggtctt
    13741 catctgtatt gctgtttgct ataacatgaa atcttattaa tttatcttta taatcttttg
    13801 atatattgtc tacttttttt acctcaccat ttattactat tgtcattatt gatatgactg
    13861 atataagact taatattaat agtcccaatc taatcttaat ttttctcatt gaaaattccc
    13921 cctcaagata aatttatatc atcaattatg tccaattaaa tttaatttat tcataatatt
    13981 ttttaatact aataaaaaaa gctatcttaa aatgattaca atcattttaa aatagctttt
    14041 taaaccttat attttataag tctttactaa tcatagcctt atctatcata aactgctctg
    14101 ctttttctat atgctctgta gcatacttct tggatagctc actatcacct ttaattatag
    14161 catcaagtaa atatttatgc tcttcaacaa tattatgtga tgtatcataa gcagacatat
    14221 aggtaactct aaatctatat acttgttccc acaatgagtt tattaattgg attaattttt
    14281 tattattagt tgctttaaat atacattcat gaaattctac atcaagtttt aataacgcat
    14341 ctacatcgga ttccaaagtg ctttttttaa attcttctga tatatcttta agctttttaa
    14401 tatcttcatc actaattctt tcagcggcaa gatatgctgc taagccttct aggcttgctc
    14461 ttacttctaa tacatccata atatccttta atgacatatt tgccacatac gcaccttttc
    14521 taggcaacat aacgactaaa ccttctaatt caagctttct tattgcctct ctcactggag
    14581 tcctacttac tcctaattgt tctgctagtt gcacttccat tagcctttga ccaggcttta
    14641 attttccttc taagattgct tctcttaaat tctcaaagac tacatctctt aatggcttgt
    14701 aattatccaa gttcagttta gttaaattct ccacaaattt caaccccttt ttgactgcta
    14761 ttaacaacat acacctgttt atattttttt aataattctt tttttccaat tagagcatct
    14821 tctttatttt taaatagtcc aaaaactgta ggaccacttc cactcatcat agaacctaaa
    14881 gcattatttt tcatcattac ttgttttata tcacttattt ctttgtgttt acctatagta
    14941 acattttcaa gaatatttac catgctttct gatacagctt ttatatcttc agattttaaa
    15001 cactctatca aatatttatt atttggtctt tttttaatat tattcaaatc taatccttga
    15061 taaacttctt tagtagaaac gaataagtct ggtttgcata tcaatatatt tgtatcacat
    15121 ggtaaacctt tgatgtttgt tagcttttct ccaatacctt gagctaaggc aggtcttcct
    15181 gatatacaaa aaggaacatc tgcgcccaaa ttaagtccta tttcttttaa ttcatcttca
    15241 gataatctaa gttcccatag gtgatttaaa cctactaata ctgcggctgc attagaactt
    15301 cctccagcca tccctgctgc tacaggaata tttttttcta tgaatatttc tacacctttt
    15361 tttatataaa atttattttt aagtattttg gcagctttat aaacaatatt atcttcatct
    15421 aaaggaatat ctaaactagt gctttttacc tttatttcat cttcgtctaa ttcttttatc
    15481 tttactatat cgtataaatc tatcgtttgc attatcattt caacaaaatg ataaccgtct
    15541 tgcctttttc ccaagacatc aatggataaa tttatttttg ctctactctt tagtcttata
    15601 aaatccattc tatcctcctt gtttaaagaa taatgcatca ctaacaataa tattatacta
    15661 caaaaaataa aataataggg tattataata ccctattata cttaattact ttaaattttt
    15721 taatattaat ctactaatac gacttttttt tctaaaataa gacacttacc aggcttaatt
    15781 ggttcatcaa gttttatatc attaagttct gcaatttcat tttctgttgt attgtatttt
    15841 tttgctatat tccagaaagt atctccttct ttgcatatat atacgattat gctaggagct
    15901 ttagataaat catatacacc ttggtcttct cccttgataa taaaattttc tgctttctta
    15961 tctaatgctt cagtaaatct cttaattttg ataatcaagt ctatctggtc cctattcaaa
    16021 tcaacttcga ctttatcaat acatgctgta ttaaacacag atgctgtatc agttagatta
    16081 tccatttcta tatcatgttc aaatggaatt tcctcactaa ttttataaac caattttaaa
    16141 ccttcaactg ggacaaataa aatttcaact tttatgattc cttgtataat gcttttattt
    16201 ccttcaatat aactattttc tatagacatg gttggacaaa cgcttacaat atcttttatt
    16261 tgtatatcat cattatcatt tcttatgcct tctctaacca taaatgtttc ttcactacgt
    16321 cttaaagtct tatttaattg aataggtttg tggtcaaatt ttattatctt ttgaggcgaa
    16381 tatgcatctt gtaatacttc tcttgtaact tcatctgtaa cttttacctt acaacaagcc
    16441 atacaatcta tttctaaaag acctgtgttg ctttcactat tttgcttgaa aatatgatta
    16501 aaatctgaca tagacaacaa tacttcttca gtcataccat cactaactcc agggacttct
    16561 acaaattgag taaactcaat acctactcta tccaactcta caagttcacc ctcatatgta
    16621 caagctaacg gatttatttc taatactcca ccaataataa ctttattgtc agtcactcta
    16681 ctttctttta ctttaacaca tggatttaaa cttattatag attgaatttc ctctgtgttt
    16741 attgttatag tatctcttat agaactttct gctttttcta ttccaactat atcttgaaaa
    16801 caaatttcct ttctgtgctt ttgtatgcct tccacttgcg ccacatcttt tacaatgtct
    16861 aacctttgct tttcaaacaa acttcccctt atattcataa gagctcctac tttaatcttt
    16921 ctctcattca ttatagtaca atccatatgc tctacttctg aaaataacat gtattccata
    16981 tcttgaacaa cattgtcttt ttctattact tcgtttatat ctacttttcc gtctacatta
    17041 gaaatagtat ttttatcatc tgcaatatag attacattat aattaaaact acctctgcaa
    17101 agtatcttcc catctgccat ttcaattttt ttaagtgata tgtatccttc tgtttttaca
    17161 atttcatata catctaattt tttgtctggt acaactgcct ccgcttcaat gaatgtttga
    17221 aattttccaa agtctattct attgtcaact ttaattacat ctttaattaa ttccatagtc
    17281 tacctcctta agtattataa aaatatcaca ctatatttat atttaaggag caaaaaaaaa
    17341 attacaccta tttttaaata ggtataattt taacttattt gtaatttatc ttgatctcta
    17401 aaaacttgca actttacatt agatgttaat aaatctgagt aactataaga tactctagga
    17461 tatccattac tttcatcatc taactttata acaaacacgc ttggataaac tttttctagt
    17521 ataccctctt ttgtaataat ctgctttctt cctttattag ctttcaacaa tattttcttt
    17581 cctatatgtc tctctaagct tactcttatc ttatctagag tttgaacagt agccacaata
    17641 tcaccttctt taacgtttat atgtttacat aatatcacat ataaacattt ttgtcaaatg
    17701 tttaaactaa ttattttata tattttttgc aaaaatgtca atactatttt tgaagatata
    17761 cagtataatt atgttaattt ttgctaatgt aatattgttt ttggcattgc ccatctaaat
    17821 tttcctctgg tttcagaacc accaattccc ttaacacctg taatagtctg ctctataacc
    17881 tcatcaatag gaactactac atcaattctt gaacaagcaa ttttctccac tataaaaaca
    17941 gggtctaatg catgtatcat tatccttcca ggcgaacttg catagtttgc tcctgcactt
    18001 attatttttt cataatttga ttggcatgct cctgcgaata tgacaagatt atccaaattt
    18061 ggttgccatt tacgtgcttc ttttactgtt ttaacaaaat ttgaagagtt tctatagtta
    18121 ctcatatctt ctatatctcc tctttttatt gtcattgcat catgacctgt tattactagt
    18181 atatccggat tatatttttc tagtagtgct cttacttctt tatactgatt ttgctctgaa
    18241 acagctacac ctactgcagg tattccaagt tgagcatata catccaagca aatttttaaa
    18301 tattctttat ctccatctat ctgtagtact tttccaggca ttccatatgt gttaggattt
    18361 aattgaagtt ttggaactgc tctagtcatt cttttttgtc tttctttagc ttttcttact
    18421 gacttatata ataaattttc tacattttta tctattaata tatcttttat atcaggtgct
    18481 tttactaatt ctaggtcatc aatataagca tctgctatta ctctaaatgc aattcccttt
    18541 agtatagcta ttttctcatt attttcatct acaccaaaag agactatttt aaatactata
    18601 tctttgttat gtgactttct agctacaatg tctcctacct tcatagttaa acctccaata
    18661 aatttttatc ttagtttata ctatgttcga tataaaactt tgtttcctaa tgtcaaaaaa
    18721 acatttctta taatacttct tttatcactc ttaaagcatt tttatagtat atcttttcta
    18781 tatcatcttc actaaaccct tcttttttta gaggttcata cagtttaccc atctgagata
    18841 tatcttcaat ctcaactttt gaatctattc catcaaaatc tgaccctaga gatacaacat
    18901 ctattcctcc aacatttaca atatgtttta tgtgtctaac catatcttca agtttacttt
    18961 cacttttatc acttaaaaat aagtggaaga agtttatacc tgtaactcca cctttatttg
    19021 ctaatacttt aatcatatca tcagttaaat ttctagaatg attcatcatt gctcttgaat
    19081 tagaatgtgt agcaattatt ggtttagaag aaatctttgc aatttcataa aatccaccat
    19141 ctgaaatatg agaaacatca accaacattc ccaattcatt catcttatgt accacttctc
    19201 ttccaaaatc agtaagccct ttttctctat attctacttt attatgagga aagctcaatt
    19261 cattcacatg attccaactt attgtcatca ttctaacccc taagtcgtaa aatttcttta
    19321 aattttctaa tttaccttca agtactgcac cttcctcaat agataaaaga gctgtaagtt
    19381 taccttctga ttggtttttc ataatttctt catagttagt agctaaagct atttcatcac
    19441 tatttttttt catttcctca tgaaatttat ttgccatact catgcaataa tcaaaaggat
    19501 gttttacttc ttcagtatca acaaaaagag caaatgtttg agctaatgaa tccccctttt
    19561 tcaatctgtc tatatcaaca gaatatttat tagacttaag ttcacttgtt tctacatttt
    19621 ccattaattt tgctatagta tcacaatgta aatcaataaa tttcatattt ataccccctg
    19681 tatattttat atttatatct aaaaatagaa atagttgtcc ttatagacaa ctattgacaa
    19741 ctatttttta atattctttt taatattact taatcttatt cttcttttaa gttaggtatt
    19801 acttttttaa cttcttcaat ttgatgccat gttttatcta tattattttc actaatatat
    19861 ttttttaaat cagttaaaga tgtaaaatct ttaactgata aattgtcatc atcatctgca
    19921 aatcttaaaa taaacatgag actcccttac tttccacaac atttcttata tttttttccg
    19981 cttccacatg ggcatgaatc atttcttcct atttttgctt ctttaactat tgttttagac
    20041 ttcttataag cctttattat ttcttttctt tggtctgctg gtagtatatc ttcccaacct
    20101 tgtaaattat atagccaatg agcctcaaca gttaccatat tgttatataa tttttcccaa
    20161 tctattttta tagaaacttc tttatcagct tctacttctt ctaaaactat atcttctttt
    20221 aagctttcac ttattccatc tatgaatccc atgaaaaatt cattagtagt tccaaatttt
    20281 tcagccaatt cacttacttt accttcaaca acatccattt tattatttaa tatttcattg
    20341 tatattccag cttcaacttt caaatattct tcccagaatt ttacttctgc ttcttgactt
    20401 tcatgattat cacttaaatt tctccattca gtatataaac tcatactttt tcctcctaag
    20461 tatacctata tttttatagt ttttatagta taaaatcttt tagttagatt ggaagtttct
    20521 tctttttgat tataccatat tctatttaaa gttaactctt atattatatc ataattaaac
    20581 aattctttta atacttttat agcatactct tggtttataa aataagggct tgtcgcaatt
    20641 gttattactt tggctttttt aattaagttt tttatcttgt aaaatttgag ttcaaatggt
    20701 atatagtcca tatcacttga aaatatatcc aaatctatgt caagaacaaa ctctgattct
    20761 acttctaaat caaatccata tagactatct attattatta attctgaaaa tatgttatat
    20821 tttaaagcag gttttataaa acttcccaca tttaaaactt catttgtata tctaaataca
    20881 tcttttagat tatttacatc tacatcatag ttctcaggtt ctctagtatc cttatgttgg
    20941 tctacatgca ctaacttgca tccttttgta aactcaccct ttaacaaaga ctttgcccaa
    21001 aaataaaatg catggttatg attgtcaaac acatatatct ttttatttcc caggacatat
    21061 tcgaccatat tctccaatcc ttttgctttt atttccttat tttcatctac ttcattaaat
    21121 actacctcat tgcctaacct tacatcattt aatgtaccat ttataagttt tggaacgtat
    21181 atgctcttat tttctctttt atcatatgaa aatacattat ttcctactgg tttttctata
    21241 taaaatccac tatattcata attttccata aaactttatt tcctccattg ttatataaat
    21301 atataagtta taattttaaa aattaaaatg cacttattgt aaatcatatc atctattata
    21361 gaaaacatct tatataacta aatataatat cttctctcaa tatgtattat acaataagtg
    21421 taaaatatat ttatataaaa tatactacat tcctataaca aaaccatcag cttcaattgg
    21481 aagataacta actcttctat tcaactccac ctttccaaaa aatactaccc aatatggtct
    21541 aaaaatactt tcaattttaa ctatttcaat ctctgggatt cctcccataa acctatgagt
    21601 taatctcata gccattttat ttgcctttgc ttttactctt cgttcgtcct tatcactata
    21661 ctgcacaata ttacaatcca cattttttac aacttcatat gtaggaaaat cttgtactat
    21721 actaccagaa cctgtagaac cattcactaa aatttttaat tcatttatat cattagaata
    21781 tctcctattc ttgaaaatgg atttcgtttt gtgaatttta agtgtgataa ttttaaactc
    21841 tatataatga agtctaactt catgagcata tttgttcttt aatattagct tactaaataa
    21901 agaatttttt ccacttttag ctatctctat agcttcttct tttgtaattc ttataggtaa
    21961 cgctcttata tccataaaat cattctcttt cttatttttt tcttgtcatt tttaaaactc
    22021 tatatatata atcaaaaaat attacaatta caactgacat aactccatat ggaattattt
    22081 ttccaactat aatatcattt ctagtcaata taccataaaa tataaatcct gttattaaaa
    22141 agtacaataa tactagaaaa ccgtctattc caagccattt tatttctaaa tcttttttta
    22201 ccttagacac taatttagac atagcagttt ctccttttat agattatttt gtgtatttaa
    22261 attttcacct attctattac caatcatcca tgcaataaat gaaaaaggta tagctatcac
    22321 aagaggctct aactcaaagc tctgaactgg aaatatttta aaataaccaa aagtcactcc
    22381 accaacaatc attcctaaaa taccacccat agatgttctt cttccatttc caagaagccc
    22441 acctactata ggtacaaatg ccgaacccat ccaaatactt cctacaaata tacatgcatc
    22501 atatacattt tcaaatctaa atgctacgct aagccccata actgctgcta aacatacacc
    22561 tattctagta aactttacta attgtttctg agataactct ttttttgtaa ttcttccata
    22621 tatatcattt gctaatgtag ccccagctgc tagataatag ctatccaatg ttgatattat
    22681 agaacctaaa attcctatta taaatattac tcttattcct tgtggtaatg tatctaaaac
    22741 taaagttata tatccagcag ctggagccat ttctggataa gtagctctta ctataagtcc
    22801 tgtcatagtt aacaccatgt caaaacatat ccatagtgaa aaacaggtta ataaggctct
    22861 tcttccaacc ttaggagaat ctgctgctga aaatctttga taaaaagttg ggtctgaata
    22921 agctccaaaa gaatatacaa ttaacatcaa tgctttcata gctgacatac cctttgtagg
    22981 gtgcataagc tgtggtgcat ctttgagtgc ttctgtaaga ccttgaaacc ctcctatttg
    23041 ttcaaattga cctggcataa ccatagttaa accaaatacc atacaaaaaa acaataccat
    23101 atctgtaatg gcaactccca taagcccacc aagtactgta agtacaacga ctactcctac
    23161 cattattaat cctattaatt ctttatctat tttccatgct acgttaccta tagttcccat
    23221 agcagttatt tctccaagtt gtgcacaata tataaacatc aaaattgccc caattatagc
    23281 aacatgcttg ccataaaaac tttccagtaa atcaggaact gttatattgg ttcttatatg
    23341 aatccttgga ccaacccaca atgctaaagg cattctccca atatgtgcag ctattgacca
    23401 aactgcccat gcagatattc catatatagc cgcatactct acactaccta ctgtaccaac
    23461 tcctccatac catgatgcaa ccaaagttcc tactattaag gaccatggta aacttcgatt
    23521 tcctaggtaa taactttcca tatcttttac atttctagaa aaataataac ctattcctaa
    23581 taatataaat gcaaatataa ctataatccc attttcccaa aatgttaaca tatctaatct
    23641 ccacattctt atattttaat ttttaacttt aatatctaaa tatgaacaac tctacccatt
    23701 tccataaaaa taggtagagt tatataataa ttataagtat ttaagtaatc ttgttattaa
    23761 gcaattttat tgtttaaacc tttattttct cttttattta ttttatttaa agcataagta
    23821 gcaaatatcc ctataactgc acatactaca gataaaataa atatatatgt atatcctgtt
    23881 tgtccatatt tatctaacca attacctgca atagtgtaat aaaacgcatc tggagaaaat
    23941 cctataaatg aagcaaatcc aactactgct cctgtagttt ctaaagatat attagactct
    24001 gaaacagatg caaagtatat acctctaaat ccaaataaaa ttacacttag tattatcatg
    24061 tttattacag ctatccatat aaatcctgta ctcttaggaa taaccaagta agcagctgta
    24121 cttactgtca ttaatataaa tcctacaaac attactctta tagatgaacc aactttatct
    24181 gttataacac cagcaactgg agatgctccc atttttataa cataagttct tattattgat
    24241 aaagcagaaa ctagagtcat tggcattaca taaacttctg ataagtatgg acttaaataa
    24301 gttaaacttg agaatactaa ataagttgaa aatattataa gaccaattag ccaagccttt
    24361 ggcattgtaa ctacttttaa caatgactta atacttaatc cttcatctga tgctccacta
    24421 tcttttttct cttccactaa gaaaaataga agtataccac atattataga tgctgcagaa
    24481 tataaccata ctacatattt gaatcctact gttatttcag caaatttacc aaagaagtaa
    24541 agacctataa aagaaattaa tgtacctgat acacctgata acccttcata aaaaccaaat
    24601 attcttcctt gctctgactc acttccttgc attctaacaa ccttaacaga ggctgagaag
    24661 aaagttaata ttgttgtaaa tccccataat acaaatatta aaagtatcat actatatgat
    24721 gggaatgtag agaaataaaa tccaagtatt cctgaagcaa ttaaagaaaa agttattaat
    24781 tttctaactg agaatctatc tgcaaaccat cctcctataa aataagatac cattcctact
    24841 aatccatata aactcaataa gttccctatt tgtgtatgac ttaatgctaa agcttgttgc
    24901 attgggtcat aaaatgatga tttcatatat ggtaaactat acatagctgt tgttccaaat
    24961 gccaatatga atattatcaa aaatctttta acattatttt tgctttccat tgattctctc
    25021 tccttaaaat tttattgttt ataatctcat tcatataatt ttattttaat ttttctattg
    25081 cttgtttaaa atcatttatt atatcatttg aagattctaa tcctacagct attcttatta
    25141 gattttcccc attcatttga actaatgtat gctcttcccc taagcttgtt gctattgttg
    25201 caagctctaa agaattcatt aatcttctac tagcttggtc tcttgtcaat ccattgatac
    25261 catccttaag tttaaatgaa actacacctc cacctaaacc attcatttga gttttacaaa
    25321 gctcatattg aggatgagat tttaatgctg gatactttac caattccaca ttctcttctt
    25381 cctctaaaaa ttctgctact gctaatccat tttcacaatg ctttttcatc ctcatatcta
    25441 acgttttcat accccttaaa atcatccatg cactcattgg tggtaaagat gctcctgtaa
    25501 aacaacataa acttggccat ctaactaaat ctattaattc ttttgaacct gctactgctc
    25561 cccctaaagt atccccatgt ccatttataa acttagtaag actatgtatt actaaatctg
    25621 cacctaaatc tattggtctt tgtacaattg gtgtcccaaa agtactatca actatagcta
    25681 agcttttatt ttcatgagca atttctgcta ttgtttttat atctactaag tctaatgatg
    25741 gatttaaagg actttctata taaactattt tagtatttgg tctcattgct tcttttacat
    25801 tttgtggatt tactgcatct acaaatgtaa cttcaactcc aaatttagat aacaactcag
    25861 acatgaataa tttagtgtgt gaaaatattc catctgaact aactatatgg tcaccacttt
    25921 ttaccaatgc taatatagta gatgttattg cccccatccc tgatgtacta gatatggcac
    25981 tttctgcatt ttcaagcata gccaacttag cttctaactc tgtaagagta ggattacact
    26041 ctcttgtata cacatatccc catgtcatac acaactcttc aaaatgctct actgtctttg
    26101 cagcaaatgt tgctgtttga catattggtg tagccaatgc acctgttgtt gggtctgcac
    26161 tatgtcccca atgtattatt tttgtctcta aatcttgatt aatattgtta ctcattttga
    26221 tttcctccca ttttgactta tttatacaac gttttcccta ccaaatttca tcaatttagc
    26281 ttagtcttaa tacatttttt caagtatact tttttatttg ttataatttc taaaaatatg
    26341 acacttattt tgttttttta cagttctaat tataaactct atagtaacta tagagtcaat
    26401 atgtttttga tatttttttt acaatgttta aaatagtcag tacaaaaata ggtatatctt
    26461 agaataacta aagtcatcct aagatatacc tatttttata tcacaatata aataattaca
    26521 tataagcatt agttttttta tcataaatag atttttcaag atttatcatc ttttcataaa
    26581 tatattatag ttaaatattt taatattacc taacatctac aataaaatat actcttaaaa
    26641 taaaattata taattaaaaa tactctataa aagctaaaaa gtttttctat tcgctacatc
    26701 taaaaataat tagatagagg tataaatgta tttagtttat ttatacctct agtcttttat
    26761 aaattatatc tctactaaat tgatttttta gcacgaataa gtgtgctctt ggagatacca
    26821 gtcatcttca caacctctct atatggctta gaatttaata accccaatgc atattgtatc
    26881 tgttgattgc tgtatttctt tggcctacca tctttaaagt cctttttctt tttagcaaat
    26941 tcttttccta attgagtacg ttctattatc atatttctct caagttctgc aactgcaagt
    27001 aatgtagtca aaaagaattt acccattgaa gtattttcta aaaggcctat atttaaaata
    27061 tgaacactta cttctttagc aaataaacct tctattagtt gtattccttc tgatgtactt
    27121 ctagctagtc tatccagctt agttgcaaca agtaagtctc ccttttttag agatgatata
    27181 attttttcaa atttaggcct gtttgtagta gtgcctgtat aagtttcctt tattatttta
    27241 gcatcattat atttattcaa aatttcttgc tgttgctgat acaaactgtt gttgtctgtt
    27301 tgattttttg tacttacacg gcaatatcca tatataataa tcatcacttc ctaacataaa
    27361 gattttgtac agaagttacc cagaagcttg tttttactta tctttatcca ttttactaaa
    27421 acgatttttg ggtgtcaata ctgttaactt ttgacaccat aataattcct ttataatttg
    27481 tttgactatg tcaaaaatta ccaatataat gaaattaatg agtttataca aattggagga
    27541 aataatatga atagtctgtt aaaagaagca atagatgaat taaaaaacat ccattgcggg
    27601 gaagtttttt tattaaaaga attgttcaaa ggctatgaat ggaacaggtt ggagatgaat
    27661 atcagattga aattaggaaa actttttttg tatgaagtgg taactaatcc caatttaaat
    27721 gtagaggtca tcaataaaaa ttctgcttat cagcaaatgt ataaaaaaaa atagtgactt
    27781 aaatgtatat aatagtataa tct
//
LOCUS       DAEPHU010000058        27746 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 01A10CD0081
            SAMN05941466-rid12468953.denovo.058, whole genome shotgun sequence.
ACCESSION   DAEPHU010000058 DAEPHU010000000
VERSION     DAEPHU010000058.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941466
            Sequence Read Archive: SRR6291087
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 27746)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 27746)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068158.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 22:43:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,892
            CDSs (total)                      :: 3,805
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 87
            rRNAs                             :: 8, 1, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 55
            CDSs (without protein)            :: 55
            Pseudo Genes (ambiguous residues) :: 0 of 55
            Pseudo Genes (frameshifted)       :: 21 of 55
            Pseudo Genes (incomplete)         :: 28 of 55
            Pseudo Genes (internal stop)      :: 16 of 55
            Pseudo Genes (multiple problems)  :: 8 of 55
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..27746
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941466-rid12468953.denovo.058"
                     /strain="01A10CD0081"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            complement(<1..391)
                     /locus_tag="KR231_002568"
     CDS             complement(<1..391)
                     /locus_tag="KR231_002568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009904849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0004932.1"
                     /translation="MSIKVAYGGVLLALNVILLTLTNIIPVNTLFIMGLASLLVSIVI
                     MEWGFKSGIAFYIGSIVLGFIVMASKSQWIVYSLTFGIYGIVKYLIEKDRSIYIEYFM
                     KLVFANIMILILYFLLRTIVYIPINIFI"
     gene            complement(402..845)
                     /locus_tag="KR231_002569"
     CDS             complement(402..845)
                     /locus_tag="KR231_002569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0004933.1"
                     /translation="MYSNTYNNENFMRARSFIENSEFKKAYDFLKTLTDKCAEWYYLT
                     GFSAMNIGYYEEGEDFLKRAKFMEPENSEYSDALRSYTQYRNDYSNRADNYNRRRRND
                     LDGCCCCCCDDCCCCLGDDCCENCAKLWCLDSCCECFGGDLITCC"
     gene            complement(835..1674)
                     /locus_tag="KR231_002570"
     CDS             complement(835..1674)
                     /locus_tag="KR231_002570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0004934.1"
                     /translation="MFGYVKINKMDLTFREYDYYKAYYCGLCKYLKRNHGEISRFSLN
                     YDITFLIVLLTAVYNPESISTEEVCIVNPFKKKKVITNDITEYAASMNILLTYYKLED
                     NLMDDKRIKDKLAYYIYKNKLKLAYEKYPEKAEYIKQQLNELNKLEKDKNINIDEVSS
                     IFGNIMGEVFVYKKDENERNLRMIGFNIGKYIYLLDAYEDLDEDFKKGRYNPFIEYID
                     KNDELKEKVKKIIVTSLGFLARGIDNLNLNKNVGIIENIIYSGVYLRYINILESRGGK
                     NVQ"
     gene            complement(1893..3278)
                     /locus_tag="KR231_002571"
     CDS             complement(1893..3278)
                     /locus_tag="KR231_002571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HBH0004935.1"
                     /translation="MDNLNKKFLMEYIDEIQGELRDISDKIWKNPELQYKEYYASNLQ
                     KECLKKHGFSIEGLEGMDTAFVASYGEGRPVIAVLGEYDALDGLSQKVSTTKEPIVDG
                     GAGHGCGHNLLGTGSIGAVIAVKELIKLKKLKGTIKYYGCPAEEDLSGKVLMIKKGFF
                     DGIDCAFSWHPFDINTPIRIPTLANYSVKFRYNGISAHAAQAPYNGRSALDAVELMNI
                     GCNYLREHIFDNCRVHYVTTNGGKMPNIVPDFAEVWYYIRGVKMEHVRDVFGRIVDIA
                     KGAALMTGTIMEYDIISGVYDYIPNTILTDILSQNMKLVGVQNYNEDDYYFADKLAET
                     VSIDKRSSVSSVLSGNKDITKMNLHDEVTDDTFTHNNCISLSLDIGDVSYIIPTAQCS
                     CSVWPIGISAHTWQSCASAGSDMGFKAMLLASKSISCSINDVMLDELVINKAKKELKD
                     TVGSFKYIPII"
     gene            complement(3451..4194)
                     /locus_tag="KR231_002572"
     CDS             complement(3451..4194)
                     /locus_tag="KR231_002572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytoplasmic protein"
                     /protein_id="HBH0004936.1"
                     /translation="MKKVLIVGESWVKNITHIKGFDTFVTTHYEEAVKWLKEAIESGG
                     YETVHMPAHVAADSFPYKLEELNEYDCIILSDIGSNTFLLSNSTFIDCNSNPDRLELI
                     KEYVNNGGALIMVGGYMSFTGIDAKARFGETAIKDVLPITMIDKDDRVEKPAGIIPEV
                     IDSEHPVLKGIPTEWPKFLGYNKTVARDNCPVLATIGGDPFVAVGEFGKGKSAIFSSD
                     CAPHWGPKEFTDWKYYNKLWVNMLDWLTC"
     gene            complement(4214..5476)
                     /locus_tag="KR231_002573"
     CDS             complement(4214..5476)
                     /locus_tag="KR231_002573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallopeptidase"
                     /protein_id="HBH0004937.1"
                     /translation="MKKILLDTLNSKKQEYIDYLKELVSIKTEDVGHGILGGFEKEGQ
                     EYIEKLANYIGFSVDRQEMSEELIKKAKNIYKEGNLGHNYQDRYNLICKYSDDLPGKT
                     IVFNGHVDTMPPGDISKWKYNPYRATEDNGKLYGLGTADMKSGLIASILAVKLIKDSG
                     LNVPGNVKIMSVVDEEGGGNGTINAVMNGIDGDCCIICEPSEQNLIVAHMGFVFFEVE
                     VKGVSLHCGSKWEGVNAIEKAMLLLQDIKELEHNWLMIYKHPLLPSPTINLGVINGGT
                     AGSTVPDKCVFNLCVHFLPNIMSYEQVVNDVTNVIMTRANGDLWLKDNKPNINIYQSG
                     LGFEMDKDSDFVVNAHKILEETLGKKLEIKGSTAGNDARVMKNLAEIPTLILGPGSIE
                     QCHSIDEYVEIKEYLDSILMYASLILNL"
     gene            complement(5660..6658)
                     /locus_tag="KR231_002574"
     CDS             complement(5660..6658)
                     /locus_tag="KR231_002574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose ABC transporter permease"
                     /protein_id="HBH0004938.1"
                     /translation="MSSITKHKEEKSSPLLTKLTSVFRDQGSAAVGLVIIFIIMSVAS
                     SNFLTLDNLINVGRQISINAILAVGMTFVIITGGIDLSVGAVIALVGTFWATTVVNYN
                     APIWVGMILALAIGTILGVIKGAIISTQKLPPFIVTLAMLTIISGASFVFTGGRPISV
                     NTDAFKMLGRGYIGPIPIPVIIMIIVVIAGHFLLKRTNFGRHVHAVGGNEEAARLCGV
                     KVNKVIVKVYALAGLLTALAGIILSSRLASGSPTVGDGAELDAIAAVVLGGTNMMGGS
                     GSIVGTCIGVGIIGILGNGLNLLSVSSYNQMIIKGLVMLFAIWINNIKLKKSAKSK"
     gene            complement(6642..8153)
                     /locus_tag="KR231_002575"
     CDS             complement(6642..8153)
                     /locus_tag="KR231_002575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter ATP-binding protein"
                     /protein_id="HBH0004939.1"
                     /translation="MSNIILKLSNIAKEFPGVRALDNVNFELFHGEVHALLGENGAGK
                     STMIKILTGAHSKTSGKFIFEGKEIENISPDISKKIGINAIYQELTVFDELTVAQNIF
                     MGKEINGKVLTNDKKMNEEAKKIFDNMGIDINPNSLVKELSIAQKQMVEIARVLSSET
                     KVLIMDEPTSSISKKETEILFRLINDLKESGVSIIYISHRMEELFEICDRITIMRDGK
                     TISTLNTKDVSSEEELVNLMIDRKLDQFFPKRKVEIKEEIMRVENLTKNNVFNDISFN
                     IRKGEILGIGGLVGSKRSEIVEAIFGLRTYDSGKIYLNNEEVKFKTPSDAIENGLGLI
                     TEDRKGTGLFLQMSVKENTTMAGLKKISKFKSIIDRKKEKEILEKYIEALKIKTPHMN
                     QVIQSLSGGNQQKAIIARWLLLQPDILIMDEPTRGIDVNAKAEIYNLMGDLVESGVSI
                     IMISSEIPELISMSDRIMVMREGHISGFLEGEEMVENNVLKLAFGGKINEFNN"
     gene            complement(8207..9169)
                     /locus_tag="KR231_002576"
     CDS             complement(8207..9169)
                     /locus_tag="KR231_002576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="substrate-binding domain-containing protein"
                     /protein_id="HBH0004940.1"
                     /translation="MRVRKILSLGIAGILAIGMLTGCSMEGPSKSDNKGGSDKKDLTI
                     GVSTITLQHQFFIDIDEGIKEKAKELGVKVIVNDPDQDVAKQTSAIEDFIQQNVDGMI
                     VLGTDNSAIVPAVEGAFEKMPVVTVDAVLNTENITSYVGTVSYDAGKKLGEYTKKYID
                     EKLGGKSEIAIVTDLKSQIQMQRIDGFKDALKGSANVKILNSQPGYDREESLNTVENL
                     IQSNPDVDIIYATAENSVLGAKAALESAKNKDVKIVGFDLTEEASSGITDGTILAMIQ
                     QQPKEMGRLAVEAVVKAIKGEKVEKNIPVPALLYDKENIKDFKN"
     gene            complement(9217..10107)
                     /gene="rbsK"
                     /locus_tag="KR231_002577"
     CDS             complement(9217..10107)
                     /gene="rbsK"
                     /locus_tag="KR231_002577"
                     /EC_number="2.7.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribokinase"
                     /protein_id="HBH0004941.1"
                     /translation="MGNIVVIGSVNMDMVCSVDKRPEKGETVLGNSFFTSPGGKGANQ
                     AISASKLGANVKMISCIGEDGLGEELIRNFRTNKVDYSLVSRNNHKSSGVAVITLCEN
                     DNSIVVVPGTNELVDIELIKKNEEEIKNADIVLLQLEIPLKTINYVVNFCFENRIRVL
                     LNPAPAVKLNEDIIEKVTYLTPNEHEYKIVFDTNEGIEEVLKKYPNKLVITEGKNGAR
                     FYDGEEIKHVSCISVDVQDTTGAGDTFNGALAVAITEGKNLYTAVEYAVVVSGLSVTK
                     LGAQSGMPYKEDVEKYLNNK"
     gene            complement(10149..11162)
                     /locus_tag="KR231_002578"
     CDS             complement(10149..11162)
                     /locus_tag="KR231_002578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009904841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HBH0004942.1"
                     /translation="MSITIKEIGELAGVSKTTVSKVINNKDENISQATREKILKIMKE
                     KNYVPNKLAQSLVTKKTNTIGLLIPDIRNPFFTDVSRGVEDKANEEGYNIILCNTDED
                     AKKEYEGIRTLSERMIDGIIFAASSNTNWKEANYKDIKIPTVLIDKKISMNKETLKGI
                     VKINNFEGAYIATKHLLDIGNKKIIYLSGPLQNEIAVDRLEGYKKALIECNLSYNPAY
                     VFEGKYKIEWGQEFIKNLEKIDFDAIFCANDLIAIGVIRGLKERGLSIPNDISVVGFD
                     DIQTSSLISPSLTTVKQPSYDIGYKASEILINCLRGDKKESFDELIFKPELVIRDSTK
                     ESE"
     gene            complement(11390..12367)
                     /gene="bioB"
                     /locus_tag="KR231_002579"
     CDS             complement(11390..12367)
                     /gene="bioB"
                     /locus_tag="KR231_002579"
                     /EC_number="2.8.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895370.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin synthase BioB"
                     /protein_id="HBH0004943.1"
                     /translation="MEKYIIKLKNKVLREKEISYEEALNLISLDTNNKNDFDILLKSA
                     NEIREYFMGRKADLCTIMNAKSGKCSEDCKFCAQSSYYKTGVEEYSLLDYNEILNRAK
                     EMESKGVHRFSLVTSGKGMSGKEFNNILNIYEGLRENTNLKLCASLGIIDYEQAKMLK
                     SAGVTTYHHNVETCRDNFHNICTTHTYKDRIKTIKDAKKAGLDVCVGGIIGMNESEEQ
                     RLKMAFEIRELNVKSFPINILNPIKNTPMENYDVLEPMEILKTTAVFRFIIPNVYIRY
                     AGGRLSLKGYDKVGFNGGVNSAIVGDYLTTVGSGIENDKKMIIEQGFEL"
     gene            complement(12573..12836)
                     /locus_tag="KR231_002580"
     CDS             complement(12573..12836)
                     /locus_tag="KR231_002580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0004944.1"
                     /translation="MKIYYEKENSKKANVNNIPSVFAFNFLRNFLTSKEYEETRKEYF
                     INNLTKSQVNQAMKDLKWLFREYEGLEVITMESLDGVKTRIVL"
     gene            complement(12906..13979)
                     /locus_tag="KR231_002581"
     CDS             complement(12906..13979)
                     /locus_tag="KR231_002581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF362 domain-containing protein"
                     /protein_id="HBH0004945.1"
                     /translation="MEKSKVYFCDLYSNSQNKNVPNNVRRLFDEAGFKDLIEKNDQVA
                     IKLHFGEKGNTTYMSPVAVRQVVDKVKDCEGKPFLTDTNTLYTGSRTNSVDHLTTAIE
                     NGFAYAVVNAPVIIADGLYSRNYENVKIDKKHFESVKIGGEIYNSSAMIVMSHFKGHE
                     AAGFGGALKNLAMGCASAAGKQMQHSDVTPVVKEKKCVGCGKCVNSCPTKAISIVDKK
                     AVIDSDVCYGCGECPTVCPTRAVTIQWESDSDVFVEKMAEYAYGAVSNKKDKVGYITF
                     VMNVTPLCDCVPWSGRPIAHDIGILASTDPVAIEQACYDLICKEMGHDVFKHEHPHVN
                     GTRIIDYACEMGMGSKEYELIKL"
     gene            complement(14238..14996)
                     /locus_tag="KR231_002582"
     CDS             complement(14238..14996)
                     /locus_tag="KR231_002582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421051.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBH0004946.1"
                     /translation="MREYIAFTKKEFKENLRNYKLFSLIILFLIFGISSPISAKFMPD
                     LIAHFAPTLKVTAAPTALDSWTQFFSNISGLGMSLTLIIFCNILSNEYSKGTLVIMLT
                     KGLSRSSIVLSKFSVTVIIMTIGFWLSFLFAYGYTMYFWPTANLNHIIFSAFNLWLIG
                     IMYISVLILGCVLFRPAFASVLLVLVATLLLSLISIPKQIAPYTPNFLMSKNIDLISG
                     KVAMPEFIIPIIITVLISIVCLLAAVILFNKKPV"
     gene            complement(14993..15910)
                     /locus_tag="KR231_002583"
     CDS             complement(14993..15910)
                     /locus_tag="KR231_002583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH0004947.1"
                     /translation="MNIVSINGLSKGFGNRKIIDNLNFTVPEGSVFGFVGKNGAGKTT
                     TMKMVLGLLKPDSGTIDVCGEKVTYGKTSSNRHVGYLPDVPEFYNYMRPLEYLSLCGE
                     ITGLSKKEIQIRSEELLSLVGLRNEKRRIGGFSRGMKQRLGIAQALLSRPKLLICDEP
                     TSALDPVGRKEILDIMLKIKDSTTVIFSTHILSDVERICDHVAILNKGSIALSGTLSE
                     IKSMHGKDRLLLEFASNDEIQKFKSSDGIKSLLKDSEETNMEIVLHGKDIKAIQKTVI
                     STLAEMNLCPVKMELIELSLENLFLEVVK"
     gene            complement(15910..16110)
                     /locus_tag="KR231_002584"
     CDS             complement(15910..16110)
                     /locus_tag="KR231_002584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421047.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLDc_N domain-containing protein"
                     /protein_id="HBH0004948.1"
                     /translation="MENLMEYLPLLVPVIILDLILIITALVHVLRHPNYKIGNKAIWI
                     IVVLFISLIGPILYFTIGRGEE"
     gene            complement(16115..17209)
                     /locus_tag="KR231_002585"
     CDS             complement(16115..17209)
                     /locus_tag="KR231_002585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBH0004949.1"
                     /translation="MNELNIAKTLILKRKEKGITQDELANYIGVSKASVSKWETGQSY
                     PDITFLPQLATYFNITVDELICYEPQMMKEDINKLYNKLCKDFTVKPFDEVMDEIREI
                     IKKYYSCFPLIFRMGLLIVNHYDIVDEKKRELLISEALEIFIRIQETCNDIDICRQAK
                     SMEATCYILLNQPIQVIDLLQNSNFPMINESILLAQGQMMNGQMDEARETFQLGAYQN
                     LISLVQNLVGILQNADKLQMKEIERRILAISDIFELDTLSPAIMLSSYLTQAQINLIH
                     GDNEGAIKSLRKYVDLATRDIYPIIIHGDDFFNKLDRWISEIGTGITRDDTIVKAGIV
                     AAIKNNPMFSVLSENKEYKFLIEKLSLLEE"
     gene            complement(17719..17859)
                     /locus_tag="KR231_002586"
     CDS             complement(17719..17859)
                     /locus_tag="KR231_002586"
                     /inference="COORDINATES: protein motif:HMM:NF021468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2185 domain-containing protein"
                     /protein_id="HBH0004950.1"
                     /translation="MNGEGCILSNKITKECYKVGYMIREKSIDIYPDSGWGFMTWDEN
                     GE"
     gene            complement(18169..19476)
                     /locus_tag="KR231_002587"
     CDS             complement(18169..19476)
                     /locus_tag="KR231_002587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallopeptidase"
                     /protein_id="HBH0004951.1"
                     /translation="MDISRSVDNSLNRTIEFLKELIKIDSQQGEPISQCPFGIGPKKS
                     LDKTLDYCASLGFSVKNIDNYIGYAEIGEGEELIGIPMHLDIVPPGEGWSVDPFSGAV
                     IDNIIYGRGVIDNKGAVSMLIHVLKNIEDMYPTINKRIRLIFGTNEETGMKCIKYYLD
                     KGEEIPSMGFTPDAMYPVVNGEKGRVHIRIEKEIKIDKSKPYIIVSGGTKENVVPSHC
                     TAKIINGIISELTTKGVAVHASNPEKGENAISKMVIKIVEDNMDFQHREDIELVSKYL
                     CSDYYGDALGINQYDEVFKNTTLNLGILKVNEEKIVCELDIRYGKNIVLNNIIDRFKK
                     VFCNGWKIEVIVHKDLHYVDESNLVLKKLLEAYEEVTDENGYTIAMGGGTYASWFKDM
                     VAFGPKFLAYKTGGHGVDERVPINHIRKNMEIYTLALIKLLEL"
     gene            complement(19541..20020)
                     /locus_tag="KR231_002588"
     CDS             complement(19541..20020)
                     /locus_tag="KR231_002588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729131.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-2-amino-thiazoline-4-carboxylic acid
                     hydrolase"
                     /protein_id="HBH0004952.1"
                     /translation="MSEKMYTEKEYLEGIRGATGERAVWFYLLMKEAEKLGANPDDIC
                     KEAIYGFGKMRGQKYNVADTPGKMAEMLYNSKGQKVFEMELVENTDENGVLKFHHCPL
                     DAAWKEYGLTKEERKEICRLACYGDYGRVDCAQGVKLDFAQKCAHDDEVCELVFTKK"
     gene            complement(20067..20930)
                     /locus_tag="KR231_002589"
     CDS             complement(20067..20930)
                     /locus_tag="KR231_002589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HBH0004953.1"
                     /translation="MQEIKNKEVKNGQGPTEVNKTRVLTKKDVTKTYLRWWWTAELSN
                     SFERMQALAVCASFTPALEKLYKRKEDLVDALKRHLQFFNTQAIWGGLIHGTVLAMEE
                     EKATEGKIPGEVISGVKNGLMGPLAGIGDTLDFGTFQTIFLALGASFGAEGSVIGAFF
                     PIMFSILLFCEGYYLFHLGYSLGRDSIKKILSGGIVNKIIDGASILGMFMMGALSATT
                     VKLSTPLSFDIGGKAIVVQDTLNMIAPGLLPLGVVFFVYWGMKYKKWTITKLLVILVV
                     LALVGSFIGIF"
     gene            complement(20930..21685)
                     /locus_tag="KR231_002590"
     CDS             complement(20930..21685)
                     /locus_tag="KR231_002590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBH0004954.1"
                     /translation="MESVLMLAIVTGLWYWFAAGLAGYTLFSTLKSPLFIGFSLGLLW
                     GDVTTGMIVGASIEMVYLGMVAAGGNIPSDKCLAALIAIPVALQTGVNAEVAVSIAVP
                     LGVIGVLVNNLRRTGNAVLVHKADKYAEEGNTKGIWRCATLYSLIFGFVLRFPIVFVC
                     NFFGADLVQSLLDVIPQWLMNGLTVMGGILPALGFATTIFTIGKNKFLPMFIIGFFMV
                     QYFEISITAAAIFGVCIALLITFMKEDKRVGEV"
     gene            complement(21712..22200)
                     /locus_tag="KR231_002591"
     CDS             complement(21712..22200)
                     /locus_tag="KR231_002591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBH0004955.1"
                     /translation="MAKITLVRVDHRLIHGQVITKWVKIAQAQKIIIVDDFLGQDEFM
                     ADIYKMAAPSGVEVVILTAEDAGQAFQNNTLGDKNIFILFKNVDMANKAYKAGLKYEK
                     IQLGGIPNEAGKKMVFTAVSLGNEDVEQLNELNENGVEIVLQVIPEESSMTYENALKK
                     FK"
     gene            complement(22218..22619)
                     /locus_tag="KR231_002592"
     CDS             complement(22218..22619)
                     /locus_tag="KR231_002592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose transporter subunit IIC"
                     /protein_id="HBH0004956.1"
                     /translation="MNKYKVIILCHGTWGKVLVEETNKNFGLSNQYEVLSLSSEKDVS
                     VFMKEVEEVVDKEDVKIIISDLYGGSTSSVAIAVAIRRGIDAINGLSLQTILIVDEEL
                     SKEDKLHTLPERIVKKNNNLCVDLIKEFKKI"
     gene            complement(22622..23119)
                     /locus_tag="KR231_002593"
     CDS             complement(22622..23119)
                     /locus_tag="KR231_002593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBH0004957.1"
                     /translation="MSLVKYCRCDDRLIHGQVIYKWVKHLGVKKIVVVDDETTNDVIA
                     KGLIKMAAPKNIDLSILTVSESRRYFYNNQADDNVFVLIKNLDTANRMIEEGINIKKL
                     IVGRIPTGIGKKKISQNVYINKKEFLLIDEFIKKNINVSIQMVPDEEEVELNQNINRY
                     KGEFI"
     gene            complement(23143..23547)
                     /locus_tag="KR231_002594"
     CDS             complement(23143..23547)
                     /locus_tag="KR231_002594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBH0004958.1"
                     /translation="MIGIIVMTHGSFSEEIIKSCELIAGPAERTAAIKLNRNDNIEDL
                     NKNFVEKLNELDEGDGVLVLADLLGGSPSNVASLNLKKGGKFHALTGVNLPMLLEALI
                     NREGKSLEELAEACIEAGQTGINNINKVLSSM"
     gene            complement(23777..26344)
                     /locus_tag="KR231_002595"
     CDS             complement(23777..26344)
                     /locus_tag="KR231_002595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425173.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HBH0004959.1"
                     /translation="MTQKKLSRKEKVLICLKRLTEEHLNFNNGIRFGFDAEYIATEVG
                     INRSNASKELNQLIKESIIIKIKGKPVQYLYKESIESILGKKLNKGIFDNINSINEYS
                     ENDSIKDEYILESIKKENNIFNLVGCDGSLRSQIEQAKAAVIYPPKGLSTLIIGPTGV
                     GKSIFAEYMYKYSLTIKEDSDNAPFIIFNCADYSDNQQLLLAQLFGYVKGAFTGADKD
                     KYGIVHEANNGVLFLDEVHRLSAEGQEMLFLLMDKGIYRRLGEANKVHECRVMIIAAT
                     TEDPETAMLETFLRRIPVTIKIPSLEERGFQERMKLICYFFKEESVRIGVKLKVSKEV
                     IKAFILYKCKGNIGQLKSDIQLICARAFLDYMTYKRECVYVRLSLLPNNIRESLYGNN
                     RKEEFVQNFSFIGKDDIIFLPEEKDFESENLLIENKKYDLDFYGMIKETWNKLQQEGI
                     KESQIRSVIDGDIQKYSYNLMNTFIYNSSNQTAYNNIVNDSIATTVKYILQKHDKWSK
                     REGLDKLIKAIALHIQNLIERIKIGNIVKHPNKDEIMKERAYEYNIAKEILSNMSLMY
                     GVEFPEDEAIFLATFLYLSYVGLNEESIAILVIMHGESTASSMVNVANTLLDCNHAVA
                     INMGLEDRVQDILVQAVEIANKIDKGKGILILTDMGSILTFAKVIRDATGKEVKAIDM
                     VSTPIVIEATRKALTPEMTLEKLYFNIIESIKKHYGDMEVTYAEKDNGGRYFDRLLID
                     NISKTLTFLNGEKAYFILKEVINRISEHYSLVIQDELLVKFIFHCSCMIERVIIKESL
                     VYKSYEERISRNKELYLVIKESFKLVEETFDIIISDMEYANILDIFESQYDTDKFKS"
     gene            26510..27253
                     /locus_tag="KR231_002596"
     CDS             26510..27253
                     /locus_tag="KR231_002596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase"
                     /protein_id="HBH0004960.1"
                     /translation="MNFLSDLHTHSIVSGHGYSTLLENINYCKENGIKILGTSEHGPK
                     MPGSPHRWYFHNIQNIPRIINNIIILRGCEANILDIKGNIDLEPFVIPRLDYLILSFH
                     EAVFSPNTLENNTKALINAINKHDNIEILGHLGNPNYPIDYELIIKLAIEKNILIEIN
                     NCSIKGVSRNGSSDNCKYIATLCKKYGAKIILTSDAHICFDIGNYEYSENILKEINFP
                     DELIMNYPKKLINHFHQKGKLLDVDYTNI"
BASE COUNT         8783 a         5209 c         2819 g        10935 t
ORIGIN      
        1 taataaatat gtttattgga atataaacta ttgttcttaa taaaaaatac aatataagta
       61 tcattatatt tgcaaatact aatttcataa aatactcaat atatatagac ctatcttttt
      121 ctataagata ttttacaata ccatatattc caaaggtaag tgaatataca atccattgag
      181 acttacttgc catcactata aatcctaaaa ctatagaacc tatataaaaa gcaattccac
      241 tcttaaagcc ccattccatt attacaattg atactaaaag tgatgctaac cccataataa
      301 acaatgtatt tacaggaata atgtttgtaa gagtcaacaa tatcacattt aatgctaata
      361 aaactcctcc ataagcaact tttatactca tatttatcat cctaacaaca agttattaaa
      421 tctccaccaa aacattcaca acatgaatct aaacaccaaa gtttagcaca attttcacaa
      481 caatcgtcac ctagacaaca acagcaatca tcacagcaac agcaacaaca tccatctaaa
      541 tcattacgtc ttcttctatt ataattgtca gccctattgc tataatcatt tctatattgt
      601 gtataacttc taagtgcatc actatattca ctattttcag gctccataaa ttttgctctt
      661 tttaagaagt cttcaccttc ttcataatat cctatgttca ttgcagaaaa accagttaaa
      721 taataccact ctgcacattt gtcagtcaaa gtttttaaaa aatcatatgc ttttttaaat
      781 tcactatttt ctatgaatga tcttgctctc ataaaatttt cattattata agtattactg
      841 tacattcttt ccacctctac tttctaatat attaatatat cttaaataaa caccagaata
      901 aattatattt tctattattc caacattttt atttagattt agattatcaa ttcccctagc
      961 taaaaatcct aatgatgtta ctattatttt ttttactttt tcttttaact catcattttt
     1021 atcaatatac tctataaatg gattatatct tcctttctta aaatcttcat ctaaatcttc
     1081 ataggcatct agtagatata tatacttacc tatattaaaa cctatcattc ttaagtttct
     1141 ctcattttca tcttttttat agacaaatac ttcacccatt atatttccaa atatactaga
     1201 tacttcatct atatttatat ttttatcttt ttctaactta tttaattcat ttagttgttg
     1261 ttttatatac tctgcttttt caggatactt ttcatatgct aattttaatt tgtttttata
     1321 tatataatat gccaatttat cttttatgcg tttatcatcc attaaattat cttccaattt
     1381 ataatacgtt aaaagaatat tcatacttgc tgcatattct gtaatatcat ttgtaattac
     1441 ctttttcttt ttaaatggat ttactataca cacttcctct gtacttatag actctgggtt
     1501 atatactgct gttaataaaa caattaaaaa tgttatatca tagttcaaag aaaacctaga
     1561 gatttctcca tgatttcttt ttaagtattt acatagtcca caatagtaag ctttgtaata
     1621 atcatattct ctaaatgtta aatccatttt gtttatttta acatatccaa acataaatac
     1681 tcctttttgt actatttttt atttagatta tatatagtat aacacttttt atcaagatta
     1741 tataatttac agtattctaa gaaacttaaa aaattccttc taatcattgt atcttaaatt
     1801 taaaataatt agaaggttgg gttaaaaata atattaaatt atatacttat attaactcat
     1861 acaagttagt tatgcttata tcaatttaag ttttaaataa ttggtatata tttaaaacta
     1921 cctacagtat ccttcaattc tttttttgct ttgtttataa ccaattcatc aagcattaca
     1981 tcatttattg aacatgatat agatttagat gccaataaca ttgccttaaa tcccatatca
     2041 gaacctgcac tggcacaaga ttgccatgta tgggcagaaa taccaatagg ccaaactgaa
     2101 caagaacact gtgctgtagg aattatgtag ctaacatctc caatatctaa tgataatgat
     2161 atacagttat tatgagtaaa tgtatcatcc gtaacttcat catgcagatt catcttagta
     2221 atatccttat ttccacttaa tacactagaa acactacttc ttttatctat agacactgtc
     2281 tcagctaatt tatctgcaaa atagtagtca tcttcattat agttttgcac acctactaat
     2341 ttcatatttt gtgatagaat atctgttaat attgtatttg gaatatagtc atatactcca
     2401 cttataatgt catattccat aatagtacca gtcattaatg ctgctccttt tgctatatca
     2461 acaatcctac caaatacatc tcttacatgc tccattttaa ctcctcttat gtaataccac
     2521 acttctgcaa aatcaggaac tatatttggc atttttccac cattagtagt tacatagtgt
     2581 actctacaat tatcaaatat atgttctctc aaataattac aacctatatt cataagttct
     2641 actgcatcaa gtgcacttct tccgttataa ggagcttgtg ctgcatgggc actaatccca
     2701 ttatatctaa atttcacaga gtaattagca agtgttggta ttcttattgg agtatttata
     2761 tcaaatggat gccaactaaa agcacaatca attccatcaa aaaaaccttt ttttatcatc
     2821 aatacttttc cagataaatc ttcttctgct ggacatccat agtattttat agtccctttc
     2881 agctttttta gtttgattaa ttcctttact gcaattacag ctcctattga acctgtacca
     2941 agtaagttat gtccacatcc atgacctgca ccaccatcta caataggttc tttagtagtg
     3001 gatacttttt gagacaaacc atctaaagca tcatattctc ccaaaactgc tataactggt
     3061 ctaccttctc cataactagc cacaaatgct gtatccatac cttctaatcc ctctatacta
     3121 aaaccatgtt tttttaaaca ttctttttgt aaatttgaag catagtattc tttatactga
     3181 agttctggat ttttccatat cttatctgat atatctctta attctccctg tatctcatct
     3241 atatattcca tcaaaaactt tttatttaaa ttatccatat taattatata aacctccctg
     3301 tttctaataa cttatcgatt atcagccaaa atgactaatt ttaactgatt taaaaatatt
     3361 ttctaccata caaccatttt atacaataaa acctcttgac ttgtaagttt cattttatca
     3421 agtaagaggt tttcaagttt tataaaattt ttagcatgtt aaccaatcaa gcatattaac
     3481 ccataattta ttatagtatt tccaatcagt aaattctttt ggaccccagt gaggtgcaca
     3541 gtcagaacta aagatagcag attttccttt tccaaactcg ccaacagcta caaatgggtc
     3601 tcctccaata gttgctaaaa caggacaatt atctctagct actgttttgt tatatcctaa
     3661 aaactttggc cattctgttg gtataccttt taatactgga tgttcagagt caataacttc
     3721 tggaattatt cctgctggtt tttcaactct atcatcttta tctatcattg ttattggtaa
     3781 tacatctttg atagcagttt ctccaaatct agcttttgca tctattcctg taaatgacat
     3841 atatccacct accatgatta acgccccacc attatttaca tactctttga ttagttcaag
     3901 tctatctgga ttactattgc aatctataaa agtactatta gataataaga acgtattaga
     3961 acctatatca gataatatta tacagtcata ctcatttaac tcttctaatt tatacggaaa
     4021 actatctgct gctacatgtg caggcatatg aactgtctca tatcctccag attctattgc
     4081 ttctttcaac cactttacag cttcttcata atgagttgta acaaacgtat caaacccttt
     4141 tatatgagtt atatttttta cccaagattc ccctactatt aatacttttt tcatttatat
     4201 attcctccta cttttataag tttaatatta gacttgcata cataagtata ctatctaaat
     4261 actccttaat ttcaacatat tcatcaattg aatgacattg ttctattgaa cctggcccta
     4321 atataagtgt tggtatttca gctaaatttt tcattactct cgcatcattg ccagctgttg
     4381 aaccttttat ctctaatttt tttcctagag tttcttctag tattttatgt gcattcacta
     4441 caaaatcaga atccttgtcc atctcaaaac ctaaccctga ttgatatatg tttatatttg
     4501 gtttattatc tttaagccat aaatctccat tagcccttgt cattatgaca tttgttacat
     4561 catttacaac ttgttcataa ctcattatat ttggcaagaa gtgtacacat aaattaaata
     4621 cacacttatc tggcacagta gaacctgctg ttccaccatt tattacacct aaatttattg
     4681 taggtgaagg taatagtgga tgtttatata tcataagcca gttatgttcc aactctttta
     4741 tatcttgaag caacaacata gccttctcaa ttgcatttac accctcccac ttactaccac
     4801 agtgaagaga cacaccttta acctcaactt caaagaatac aaatcccata tgtgcaacta
     4861 ttaagttttg ttctgatggt tcacaaatta tgcaacaatc tccatcaata ccattcataa
     4921 ctgcatttat ggtaccattt ccgccacctt cttcatctac tactgacatt atttttacat
     4981 taccaggtac atttagacca ctatctttta taagctttac agctaatatt gatgctataa
     5041 gtccagattt catatcagca gttccaagac cataaagttt tccattatct tctgtagcac
     5101 ggtatggatt atatttccac ttacttatat cacccggtgg catagtgtct acatgaccat
     5161 taaatacaat tgtcttacca ggtaaatcat cactatactt acaaattaaa ttatatctat
     5221 cttgataatt gtgacctaga tttccttctt tatatatatt ttttgctttt ttaattaatt
     5281 cttcgctcat ttcttgtcta tccacactaa aacctatgta atttgcaagt ttttcaatat
     5341 attcctgtcc ttctttttca aatccaccta gtattccatg accaacatct tcagtcttta
     5401 tacttacaag ttcttttaaa taatctatgt attcttgttt tttactattt aatgtatcta
     5461 agagaatttt tttcatattt cctcctaaga tttattttta catttaaaat ttcaagtcta
     5521 atctcatcta tttaagccat agtaaacttt ttcacttagc atattctcat tcaatgtata
     5581 aagatgtatg caaattaaag tataaaaata tatacaaaaa cttaataatt tttatagttt
     5641 ataagctaaa atttaattac tatttagatt tagctgattt ttttaatttt atattattta
     5701 tccatatagc aaataacatt accaaacctt ttataatcat ttgattatat gaagatacac
     5761 ttaataagtt taatccattt cctaatattc ctattattcc gacacctata catgtaccta
     5821 ctatagaacc agaaccaccc atcatattag taccaccaag cacaacggct gctatagcat
     5881 ccaattctgc tccatctcca acagttggtg aacctgatgc caaacgtgat gatagtatta
     5941 tcccagctaa tgctgttagt agtccagcta gtgcgtatac ttttactata actttattta
     6001 cttttactcc acataatcta gcggcctctt catttccacc tactgcatgt acatgacgtc
     6061 caaaattagt tctttttaat agaaaatgtc ctgctattac aactataatc ataattataa
     6121 ctggtattgg tattggtcca atatatcctc taccgagcat cttaaatgca tctgtattta
     6181 ctgatatagg tcttcctcct gtaaatacaa agcttgcccc acttattatc gttaacatgg
     6241 ctaaagttac aatgaatgga ggtagttttt gtgttgaaat aattgcacct tttatgactc
     6301 ctaatattgt ccctattgct aatgcaagta tcatacctac ccatataggt gcattataat
     6361 tcactactgt tgtagcccaa aatgtaccta ctaaagcaat tactgctcct acacttaaat
     6421 ctattcctcc tgtaattatt acaaatgtca tacctactgc aagtattgca tttattgata
     6481 tttgtcttcc aacattaatt aaattatcta aagttaaaaa gttagatgaa gctacactca
     6541 ttattataaa aattattaca agtcctacag ctgcactccc ttggtctcta aatacacttg
     6601 ttaattttgt caataatgga gaagattttt cttctttatg cttagttatt gaactcatta
     6661 attttacctc cgaaagccaa ttttaataca ttattttcaa ccatttcttc accttctaaa
     6721 aatccactta tatgaccttc tctcataacc attattctgt cactcattga tattaattct
     6781 ggtatttcag aagatatcat tattatactt acaccactct ccactaaatc tcccattaga
     6841 ttgtatatct ctgccttagc atttacatct atacctctgg ttggttcatc cataatcaat
     6901 atatctggtt gtaataaaag ccatcttgct attatagctt tttgttggtt tccaccactt
     6961 aaactttgta taacttgatt catatgtggt gtttttatct ttaaagcttc tatgtatttt
     7021 tctaaaatct ctttttcctt ttttctatct ataattgatt taaacttaga tatctttttt
     7081 aacccagcca tagttgtatt ttctttgaca ctcatttgta aaaacaatcc agtacctttt
     7141 ctatcttctg ttattaatcc tagtccattt tctattgcat ctgatggagt tttaaacttt
     7201 acttcttcat tgtttaaata tatttttcca gaatcatatg ttctaagtcc aaatatagct
     7261 tctactattt cacttctctt acttccaact agtccaccta ttcccaatat ttcacctttt
     7321 cttatattaa agctaatatc attaaaaaca ttgttcttag ttagattttc cactcgcata
     7381 atttcttctt ttatttctac ttttcttttt gggaaaaatt ggtctagctt tctatctatc
     7441 attaaattaa ctaattcttc ctcagacgat acatctttgg tatttaaagt cgaaatcgtt
     7501 ttcccatctc gcattatagt tattctgtca caaatctcaa agagttcttc catcctatgg
     7561 gatatatata ttatactaac tccactctct tttaaatcat ttataagtct aaaaagtatt
     7621 tcagtctctt ttttacttat tgaagaagta ggttcatcca ttattaatac tttagtttct
     7681 gatgataaaa ctcttgctat ttctaccatt tgtttttgag ctatactaag ctctttgact
     7741 aaactatttg gatttatatc tattcccata ttatcgaaaa tctttttagc ctcttcattc
     7801 atttttttgt cattggttaa gactttgcca tttatttctt ttcccataaa aatattttgt
     7861 gctactgtta attcgtcaaa aactgttagt tcttgatata tggcatttat acctatcttt
     7921 ttagagatat ctggggatat attctctatt tctttgcctt caaaaataaa ttttccagaa
     7981 gttttcgaat gtgcaccagt taaaatcttt atcattgttg atttaccagc accattttca
     8041 cccagtagtg catgaacttc gccatgaaat aactcaaaat taacattatc taatgctctg
     8101 acaccaggaa attctttagc aatattactt aacttcagaa ttatattact cataatgaca
     8161 ctccttttta aataggattt ctttcaaata atctcatttt attttactaa ttcttaaagt
     8221 cttttatatt ttccttatca taaagtaaag ctggtactgg tatattcttt tctacctttt
     8281 ccccttttat agcttttact actgcttcta cagctaaacg tcccatctct ttaggttgtt
     8341 gttgaatcat agcaagaata gttccatctg ttattccact tgatgcttct tcagttaagt
     8401 caaatcctac aatcttaaca tccttatttt ttgcagattc aagtgcagct ttagctccta
     8461 gtacactatt ttcagctgtt gcatatatta tatctacatc tggattagat tgaattaagt
     8521 tttctactgt attaagagat tcttctctgt catatcctgg ttgtgaattt aatatcttaa
     8581 catttgctga accttttaat gcatctttaa atccatctat tctctgcatt tgtatttgag
     8641 attttaaatc tgtcactatt gctatttctg actttccacc taacttttca tctatgtatt
     8701 ttttagtgta ttcccctaat tttttaccag catcataact aactgttcct acataacttg
     8761 taatattttc agtatttaat acagcatcta ctgtaactac tggcattttt tcaaatgctc
     8821 cttctactgc tggtactata gccgaattat cagttccaag tactatcatt ccatctacat
     8881 tttgttgtat aaaatcttct attgctgatg tttgcttagc tacatcttgg tctgggtcat
     8941 ttactataac tttcacacct aattctttag ctttttcttt tattccctca tcaatatcta
     9001 taaaaaattg atgttgaaga gttattgtag atactccaat agttaaatct ttcttgtctg
     9061 aaccaccttt attatctgat ttacttggtc cttccattga acaccctgtt aacattccta
     9121 ttgctagtat tccagcaatt cctaaagata aaatttttct cactctcata attaacctcc
     9181 atttttaata gttttaaatt tgaacaaatt agatttttat ttattattta aatatttttc
     9241 aacatcttct ttataaggca taccagattg tgcacctagt ttagttacag acagacctga
     9301 tactactact gcatattcta ctgctgtata taaatttttc ccttctgtta tagccactgc
     9361 caatgctcca ttaaatgtat ctcctgctcc tgtggtatct tgaacatcaa cacttataca
     9421 agatacatgc ttgatttcct caccatcata aaatctagct ccattttttc cttctgttat
     9481 tacaagttta tttggatatt tttttaatac ttcttctatc ccttcatttg tgtcaaaaac
     9541 tatcttatat tcatgttcat ttggtgttaa gtaagttact ttttctatta tatcttcatt
     9601 tagttttact gctggtgctg gatttaataa aaccctaatc ctattttcaa aacagaaatt
     9661 cactacataa tttattgttt ttaatggaat ctctaattgt agcaatacta tatctgcatt
     9721 ctttatctct tcttcattct ttttaattaa ttctatatct actagctcat tagtccctgg
     9781 tacaacaaca atactattat cattttcaca taatgttata acagcaacac cagaactttt
     9841 gtgattattt ctggatacta agctataatc aactttattc gttctaaaat ttcttattaa
     9901 ctcctctcct aagccatctt cccctatgca tgatatcatt tttacatttg ctcctagttt
     9961 agaagctgag atagcttgat tagccccttt tcctccaggt gatgtaaaaa aactattacc
    10021 taatactgtt tctccttttt ctggtctttt atctacagaa cataccatgt ccatgtttac
    10081 acttcctatg acaactatgt ttcccattac attactcctt tacatatcta tttatgtctc
    10141 tcgtgctgtt attcactttc ttttgttgaa tctcttatga ccaattctgg tttgaaaatc
    10201 aattcatcaa acgattcttt tttatctcct cttaaacaat ttatcaatat ttcactggct
    10261 ttatatccta tatcataaga cggctgtttt actgtggtaa gagaagggct tattagactt
    10321 gatgtttgaa tatcatcaaa tcccacgaca cttatatcat ttggtatact taatcctctt
    10381 tctttaagac ctcttatgac acctattgca atcaaatcat ttgcacaaaa tattgcatca
    10441 aaatctatct tttctaaatt ttttataaat tcttgtcccc attcaatctt atattttcct
    10501 tcaaatacat aagcaggatt gtagcttaaa ttgcactcga ttagagcctt tttatatcct
    10561 tctaatctat ctactgctat ttcattttga agtggaccac ttaggtatat tattttctta
    10621 tttccaatat ctaataaatg ttttgtagct atataggccc cttcaaagtt atttatttta
    10681 acaattcctt ttaaggtttc tttgttcata cttatcttct tatcaatcaa gacagttggt
    10741 atttttatat ctttataatt tgcttctttc cagtttgtat ttgaagatgc tgcaaatata
    10801 attccatcta tcatcctctc tgatagtgtt cttattcctt catattcttt tttagcatct
    10861 tcatctgtat tacataaaat tatattgtag ccttcttcat tagctttgtc ttctacacct
    10921 cttgatacat ctgtaaagaa tggatttcgt atatctggta taagaagccc tatagtatta
    10981 gtttttttag ttactaaact ttgtgctaat ttatttggta cataattttt ttccttcatt
    11041 attttcaaaa ttttttctct tgttgcctga cttatatttt catctttatt attaatgact
    11101 tttgacacag ttgttttaga aacaccagcc aattcgccaa tttcttttat agttatactc
    11161 aagaagttca cccccaaaat ttaggaaacc gttttactta accggttacc tagatactat
    11221 cacatctttt ttccatttgc aaccatttta tataaatttt gatatttttc ccttttttca
    11281 aaatattgca acttataatt caattttaat atttaaatta atctgaaaaa aaaattaata
    11341 tacttttata attatctaaa agtatattaa ttaatttaag cagtatttat taaagttcaa
    11401 atccttgctc tataatcatt tttttatcat tttcaatccc acttccaaca gttgtcaaat
    11461 aatcaccaac aattgcagaa tttactcccc cattaaatcc aactttgtca tatcccttta
    11521 atgatagcct tccaccagca taccttatgt acacattagg aattataaac ctaaatactg
    11581 ctgttgtttt tagtatttcc attggttcta atacatcata attttccatt ggtgtattct
    11641 taataggatt taaaatgttt attggaaatg attttacatt taattctcgt atttcaaaag
    11701 ccatttttag tctctgttct tcactctcat tcattccaat tataccgcct acacatacat
    11761 ctagcccagc ttttttagca tcttttatag tttttatcct atctttatat gtgtgtgttg
    11821 tacatatatt atgaaaatta tctctacacg tctcaacatt gtggtgatat gtagtcacac
    11881 ctgctgactt caacatttta gcttgctcat aatctataat acctaaagat gcacataatt
    11941 ttaaattagt attttccctc aatccttcat agatatttaa aatattatta aactcctttc
    12001 ctgacatacc tttaccactt gtaaccaatg agaatctatg cactccttta ctctccatct
    12061 ctttagctct atttaagatt tcattgtaat ctaataatga atattcttct acaccagttt
    12121 tataataaga agactgagca caaaatttac agtcttcact acatttgcca gatttagcat
    12181 tcattatcgt acataaatct gcttttcttc ccataaaata ttctcttatt tcatttgcag
    12241 attttaatag aatatcaaaa tcgtttttat tatttgtatc aaggcttatt aaattaagag
    12301 cttcttcata acttatttct ttttctctca atactttatt ttttaatttt attatgtatt
    12361 tttccatata tcctcctatt tgtcaactta atatttttat gtagtttact tattatatat
    12421 agtattgcat atataacatt tattggtcaa ctttatttta gacacaagtt tactatacac
    12481 aaaaaaatac tgcttcaaaa caatattagt atatagatta tacatattat tattaaagca
    12541 gtatttttta ttagaatata attcttactg gtttataaaa ctatccttgt cttaactcca
    12601 tccaagcttt ccattgtaat aacttctaag ccttcatatt ctctaaatag ccattttaaa
    12661 tccttcatgg cttgattaac ctgacttttt gttagattat ttataaaata ttcttttcta
    12721 gtttcctcat actctttgct agtcaaaaag tttcttagaa aattaaacgc aaatacactt
    12781 ggaatattgt ttacattagc cttcttgctg ttttccttct catagtaaat tttcataaat
    12841 gcatactcct ttgatacttt tagatttctc ttacaataat tatatgcatt taagtgctac
    12901 tattcttata attttattaa ttcatattct ttacttccca tacccatttc acatgcatag
    12961 tctattattc tagttccatt tacatgagga tgttcatgtt tgaaaacatc atgacccatt
    13021 tccttacaaa tcaaatcata gcatgcttgt tcaatagcta cagggtctgt tgatgctaat
    13081 attcctatat catgggcaat tggtctacct gaccaaggta cacaatcaca aagtggagtt
    13141 acattcataa caaaagttat ataccctacc ttgtcttttt tatttgatac tgctccataa
    13201 gcgtattctg ccatcttttc gacaaacaca tctgagtcac tttcccattg tatagttact
    13261 gctctagttg gacagacagt tggacattct ccacatccat aacatacatc agaatctata
    13321 actgcttttt tatccactat acttatagct tttgtaggac aagaattaac acactttcca
    13381 caacctacac acttcttttc ctttactact ggagtaacat cagaatgttg catttgtttt
    13441 cctgctgcac ttgcacatcc catagctaag ttttttaatg ctcctccaaa acctgctgct
    13501 tcatgacctt taaaatgact cattactatc attgcagaag aattataaat ttctccacct
    13561 atttttacac tttcaaaatg ttttttgtct atttttacat tctcataatt tctactatat
    13621 aatccatctg caattattac tggtgcattt acaactgcat aagcaaatcc attttctata
    13681 gcagttgtaa gatggtctac agaatttgtt ctactccctg tatacagtgt atttgtatct
    13741 gttaaaaatg gctttccttc gcagtcttta accttatcaa ccacttgtct aactgccaca
    13801 ggactcatat atgtagtatt tcccttttct ccaaagtgaa gtttaattgc gacttggtca
    13861 tttttttcta ttaaatcttt gaatcctgct tcatcaaata atcttcttac attgtttggt
    13921 acgtttttat tttgcgaatt tgagtataaa tcacaaaaat atacttttga cttttccata
    13981 tctacacccc tttaaaatat ttacttatac taattttatc acttttaaag taatttttag
    14041 tatattttaa cataattaaa tattcttata tttatttgat acaaataata ttatttgtat
    14101 tattttctac acttaattct atatattaaa ctacacctaa aaatcaaaaa gacttgaaac
    14161 ttaagtccaa gtctttttga tttttaggtg tagtttttaa caacataaga ttactttacc
    14221 ttgtgataaa ggtattatta aactggtttt ttattaaata aaataacagc tgctagtaaa
    14281 catactatag aaataagaac tgttataata attggaataa taaattctgg cattgccact
    14341 ttccctgaaa tcaagtctat attttttgac atcaagaaat taggagtata aggtgcaatc
    14401 tgtttaggaa tagaaattaa actcaataag agagttgcta ccaatacaag taaaacactg
    14461 gcaaatgctg gtctaaatag tacacaccca agaattaata cactaatata cataattcct
    14521 ataagccata aattaaatgc tgaaaatata atatgattaa gatttgcagt tggccaaaaa
    14581 tacattgtat agccataagc aaataaaaaa ctcaaccaaa aaccaattgt cataataatc
    14641 accgtaacag agaatttaga caatactata gatgaacgtg ataaaccttt agtcagcata
    14701 ataacaagtg tccctttaga atattcattt gataaaatat tacaaaaaat aattagagtt
    14761 aaactcatac caagaccaga gatattgcta aaaaattgtg tccaagaatc taaagcagtt
    14821 ggtgcagcag taacttttaa agtcggtgca aaatgagcaa tcaagtctgg cataaatttt
    14881 gcagaaatag gactacttat accaaatatt agaaataaaa taattaaact aaataattta
    14941 taatttctta aattctcttt aaattctttt tttgtaaatg ctatgtattc tctcacttta
    15001 ctacctccaa aaataaattt tcaagtgata attctattag ttccatcttt actggacaaa
    15061 gattcatttc tgcgagcgta gatataactg ttttttgtat tgcttttata tctttaccat
    15121 gcaaaacaat ttccatatta gtttcttctg aatcttttag taaggattta ataccatcac
    15181 tagacttaaa cttttgaatt tcatcattac ttgcaaactc cagtaaaagt ctatcctttc
    15241 cgtgcatact ttttatttct gaaagtgtac cactaagggc aatgcttcct ttgtttaata
    15301 tagcaacatg gtcacagatt ctttcaacat ctgatagtat atgtgttgaa aatattacag
    15361 ttgttgagtc tttgatttta agcataatat ctaatatttc ttttcgacca acagggtcaa
    15421 gtgcacttgt tggttcatca caaataagta atttggggcg tgaaagcaaa gcttgagcta
    15481 taccaagtcg ttgcttcatt ccacgagaaa acccacctat tcgtctcttt tcatttctaa
    15541 gacccacaag tgataacaac tcttcactcc ttatctgtat ttcttttttt gaaagtcccg
    15601 taatttcacc acaaagagaa agatattcaa gtggtctcat ataattgtaa aactctggaa
    15661 catcaggcag ataacctaca tgacgattag aacttgtttt cccataggtc actttctcac
    15721 cacaaacatc tatagttcca ctatctggtt taagtaaccc aagtaccatt ttcattgttg
    15781 tagtcttacc tgcaccattc ttacctacaa acccaaagac tgacccttct ggtacagtaa
    15841 aatttaaatt atctattatc tttcgattac caaaaccttt tgataatcca tttattgaga
    15901 caatattcat cattcttcac ctcttcctat tgtaaaatac aaaattggtc ctattaaact
    15961 aataaacagt actacaataa tccatattgc cttatttcca attttataat ttggatgtct
    16021 caacacatga acaagtgcag taattataag tattaaatct aaaataataa caggaaccaa
    16081 aagtggtaag tattccatca aattttccat aatcttattc ctccaataaa gataattttt
    16141 ctataagaaa tttgtattct ttgttttcac ttaatacaga aaacattgga ttatttttaa
    16201 tagcagcaac aatacctgct tttacgattg tatcatcacg tgtaatacct gttccaattt
    16261 cagaaatcca tctgtcaagt ttattaaaaa agtcatcccc atgtattata attgggtata
    16321 tatcacgtgt tgctaaatct acatattttc gtaatgattt aatagctcct tcattatcac
    16381 catgtattaa attaatttgt gcctgtgtta aatatgaaga aagcataata gcaggagata
    16441 atgtatcaag ctcaaatata tctgaaattg ctagaatacg tctttctatt tccttcattt
    16501 gtaatttatc tgcattttgc aaaataccca ctagattttg gactaatgat ataaggttct
    16561 gatatgcacc aagttgaaat gtttctcttg cttcatccat ttgaccattc atcatttgcc
    16621 cttgtgcaag aagtatagat tcatttatca tgggaaaatt gctgttttgc aataaatcaa
    16681 tcacttgtat gggttgattt aacaatatat aacaagttgc ctccatactt tttgcttgac
    16741 ggcaaatatc tatgtcatta caagtttcct gtatacgaat aaatatttct aatgcttcac
    16801 taattaatag ttcacgcttt ttttcatcta caatatcata gtgattaact attaaaagac
    16861 ccatccgaaa aatcaaagga aaacatgaat aatatttttt tatgatttct cttatttcat
    16921 ccatgacttc atcaaatggt ttaaccgtaa agtctttgca cagtttatta tacagtttat
    16981 taatatcttc cttcatcatt tgaggttcat aacatattaa ctcatcaacg gtaatgttga
    17041 aatatgtcgc gagttgcggt aaaaaggtta tgtcaggata gctttgtcca gtttcccatt
    17101 tagatacaga agctttagaa acgcctatat aatttgcaag ttcatcttgt gtaattcctt
    17161 tttctttacg ctttaaaatc agcgtttttg cgatgtttaa ttcattcatg tcaatccctc
    17221 cttatgtata attatatcct taaacatgta aagctaacaa gcgatttgaa gttgactttt
    17281 gacgaaaaaa tcaaccacag agaaacaaat aaacaagtat ataaaatata tatttaaatt
    17341 tatctttaat ctcctttgta aaatatgtaa actttgtaaa taaaatccat attatataaa
    17401 actaatagtt aatctatcta aatacagttt ttatttatca cgtttttaaa tattttgtgt
    17461 aaaacctctt ttaatataaa caccttattt tcatttctca tttcatattc tttttaaaat
    17521 actgaatata actcttcgat tttccattta atccttttat aaagttatta ttcgtattta
    17581 ttcctctaat tataacaggc aactatcatg tattggtatt tgtctattat ataaaaatct
    17641 ataaaagaaa agcagtcaat catttagatt aactgcttgt acatatatct tattaaactg
    17701 tataaactat aatttttatt attctccatt ttcatcccaa gtcataaatc cccatccact
    17761 atctggataa atatcgatag acttttctct aatcatataa ccaactttat aacactcttt
    17821 tgttatttta ttagatagta tacatccttc tccatttatc taattccatt taattaactt
    17881 ttcttttcaa ccttaacttt tataaaatca tcttttttaa taatttcata cttattttct
    17941 cttcaacatc atcaaatgag ggtgtctcaa aattaacttt ttacttcata aggcactctt
    18001 ttttgtatga agtaaaatat attttcatca tttcaacaat aagtaagagg cttatctcta
    18061 ttttgagaca gccccatttg atggtgttga acatttaaat aaggttgaac tcgttttatc
    18121 tctcttttta agatatctgt aaatttgcac ataaagtctc ttcttctttt acaattctaa
    18181 tagttttatt aaagccaaag tatatatctc catattcttt cgtatatgat ttattggtac
    18241 tctttcatct actccatgac caccagtttt atacgctaag aacttaggtc caaacgccac
    18301 catatcttta aaccaacttg catatgtgcc accacccata gcaattgtat atccattttc
    18361 atctgttact tcttcatagg cttctaataa ttttttaagt actaaattac tctcatccac
    18421 ataatgtaag tctttatgaa caataacctc tattttccaa ccattacaaa aaaccttttt
    18481 gaatctatct attatattgt ttaaaactat atttttacca taccttatat ctaactcaca
    18541 tacgattttt tcctcattta cttttaatat tcctaaattt aaggtagtgt ttttgaatac
    18601 ctcatcatat tgattaatcc ccaatgcatc tccataataa tcactacaaa ggtattttga
    18661 aactaattct atatcttctc tatgctgaaa atccatatta tcctcaacta tctttattac
    18721 cattttagat atagcatttt ctcccttttc aggattactt gcatgtacag ctactccttt
    18781 agtagttaac tctgaaataa ttccattaat aatttttgca gtacaatgag atggaacaac
    18841 attttcttta gttcctccac ttactattat gtaaggttta cttttgtcaa ttttaatttc
    18901 tttttctatc cttatatgaa cccttccttt ttctccatta accactggat acatagcatc
    18961 tggagtaaat cccatacttg gaatttcttc acctttatct aagtaatatt tgatacattt
    19021 catacctgtc tcctcatttg taccaaaaat taatcttatt cttttattaa ttgtaggata
    19081 catatcctct atgtttttca atacatgtat aagcatagat acagcaccct tattatctat
    19141 gacacctctt ccataaataa tattgtcaat tactgctccc gaaaatgggt ctacactcca
    19201 cccctctcct ggtggaacta tatctaaatg cattggaatc cctattaatt cctctccctc
    19261 tccaatttct gcatatccaa tataattatc aatattttta acactaaaac ctaaactagc
    19321 acagtaatct aaagttttat ctaaagattt tttaggtcct ataccaaaag gacattgtga
    19381 aataggttca ccttgttgtg aatcaatttt tatcaattct tttagaaatt ctatggttct
    19441 atttaaacta ttatctacac ttctgcttat atccataaat caacctactt tctatctttt
    19501 taaagcctgt ccttaaagaa caggctttta gcattaaaaa ttattttttt gtaaatacta
    19561 attcacaaac ttcatcatca tgagcacatt tttgagcaaa atctaattta acaccttgtg
    19621 cacagtcaac tcttccataa tccccataac aagctaatct acaaatttct tttctttctt
    19681 ctttagttaa tccatattct ttccaagcag catctaatgg acagtgatgg aattttaaaa
    19741 cgccattctc atctgtattt tctactaatt ccatttcaaa cactttttgt cctttactgt
    19801 tatataacat ttctgccatt tttcctggag tatctgctac gttatatttt tgacctctca
    19861 ttttaccaaa tccatatatt gcttctttac atatatcatc tggattagct cctaattttt
    19921 cagcttcttt cataagaaga tagaaccata ctgctctttc tcctgttgct cctctaattc
    19981 cttctaaata ttccttttct gtatacattt tttctgacat ttctttctcc tcctaaaatt
    20041 aaattctata ttttaatcac tgtgaattag aatattccaa tgaatgaccc taccaatgct
    20101 aatacaacca aaattactaa taacttagtt attgtccact tcttgtattt cattccccaa
    20161 tatacgaaga atacaacacc aagtggtaat aaacctggag caatcatatt taatgtatct
    20221 tgaacaacaa ttgctttacc accaatatca aatgatagcg gagttgaaag cttaactgta
    20281 gttgcagata atgctcccat cataaacatt cctagaattg aagcaccatc aattatctta
    20341 ttgacaatac cacctgatag aattttctta attgaatctc tacctaaaga atatcctaaa
    20401 tgaaataagt aataaccttc gcaaaatagt aatatactaa acattattgg gaaaaatgca
    20461 cctataacac ttccttctgc tccaaatgaa gcacctaaag ctaagaatat tgtttgaaat
    20521 gtaccaaaat ctaaagtatc tccaattcca gccaaaggtc ccataagacc attcttaaca
    20581 cctgaaataa cttctcctgg gatttttcct tcagtagctt tctcttcttc catagctaaa
    20641 actgtaccgt gaattaatcc tccccatata gcttgagtat taaaaaattg taagtgtctc
    20701 tttaacgcat ctactaaatc ttcttttctc ttatataact tttctaaagc aggagtgaaa
    20761 cttgcacaaa ctgctaatgc ttgcattctt tcaaaagagt tggataattc tgctgtccac
    20821 caccatctta gatatgtttt tgttacatct ttctttgtaa gtactcttgt cttattaact
    20881 tcagttggac cttgtccatt tttaacttct ttatttttta tttcttgcat tatacttcac
    20941 ctaccctttt gtcttctttc ataaaggtaa ttaaaagagc tatacaaaca ccaaatattg
    21001 cagctgcagt aattgatatt tcaaaatatt gaaccataaa aaatcctata ataaacattg
    21061 gtaagaattt atttttacct atagtaaata ttgttgttgc aaaacctaat gcaggtaata
    21121 taccgcccat tactgttaat ccattcatta accattgtgg tataacatct aataatgatt
    21181 gaactaaatc tgctccaaaa aagttacata caaaaactat tggaaacctt aaaacaaacc
    21241 caaatattaa agaataaagt gttgcacatc tccagatgcc ttttgtatta ccttcttcag
    21301 catacttatc tgccttatga accaatacag cattaccagt tcttcttaag ttattaacta
    21361 atactcctat aacacctaaa ggtaccgcaa tagatactgc aacttctgca ttaacaccag
    21421 tttgaagtgc tactggtatt gcaataagag cagctagaca tttatctgat ggaatatttc
    21481 cccctgctgc gaccattcct agataaacca tttctatact tgcaccaaca atcataccag
    21541 ttgttacatc accccaaagt aatccaaggc taaaacctat aaataaagga gactttagtg
    21601 ttgagaaaag ggtataccct gcaagacctg ctgcaaacca ataccataat cctgttacaa
    21661 ttgccaacat caaaacagat tccatttata attcctccta atttatattt tttatttaaa
    21721 tttctttaac gcattttcat atgtcataga tgattcctct ggtataactt gtaggactat
    21781 ttcaacccca ttttcattaa gttcattaag ttgttctaca tcctcatttc ctaatgaaac
    21841 agctgtaaac accattttct ttcctgcttc atttggaata cctcctaatt gaatcttttc
    21901 atatttaagt ccagctttat aagccttatt tgccatatca acatttttaa atagaataaa
    21961 tatattttta tctcctaaag tgttgttttg gaatgcttgt cccgcatctt ctgctgttaa
    22021 aataactact tctactcctg atggtgctgc cattttatat atgtcagcca taaattcatc
    22081 ttgacctaag aagtcatcaa ctattattat tttttgagct tgagcgattt ttacccattt
    22141 tgttataact tgcccatgaa ttaatctgtg gtctactctt actaatgtta tttttgccat
    22201 tatattcacc tcataattta tattttttta aattctttaa ttaaatccac acaaaggtta
    22261 ttattttttt tgacgattct ttctggtaat gtatgtaatt tatcttcttt gcttaattct
    22321 tcatctacga ttaaaattgt ctgtaagcta agtccattta ttgcatctat tcctcttctt
    22381 atagcaacag ctattgcaac acttgatgta gatcctccat ataaatctga tattataatt
    22441 ttcacatctt ctttatctac tacttcttca acctctttca taaatacaga aacatctttt
    22501 tcagaactta gtgataaaac ttcatattga tttgacaatc caaagttttt atttgtttct
    22561 tctactaaga cttttcccca agttccatgg cacagtatga ttaccttata tttattcatt
    22621 gctaaataaa ctctccttta tagcgattaa tattttggtt taattctact tcttcttcat
    22681 caggtaccat ttgaattgat acattaatat tctttttaat aaattcatct attaaaagaa
    22741 actctttttt attaatgtat acattttgag atattttctt ttttcctatt cctgtaggta
    22801 ttcttccaac aataagtttt ttgatattaa tcccttcttc tatcattcta tttgcagtat
    22861 ctaaattttt aattaataca aaaacgttat catcagcttg attattataa aaatatctcc
    22921 ttgattcact tacagttaat attgataaat caatattctt tggtgctgcc atttttatca
    22981 aacctttagc aataacatca ttggttgttt catcatctac tactactatc ttttttacac
    23041 ctagatgctt aacccattta tatataactt gaccatgtat taatctatca tcacatctgc
    23101 aatattttac taaagacatt tttaatcaaa ctcctttttc tattacattg agctaagaac
    23161 tttattaata ttgtttatac cagtttgtcc tgcttcaata catgcttctg ctaactcttc
    23221 taaacttttt ccctctctat taattaaagc ttcaagtagc attggaagat ttactccagt
    23281 aagtgcatga aacttgccac cttttttaag gtttaaactt gcaacattac ttggcgaacc
    23341 tcctaatagg tcagctaata ctaaaactcc gtcaccttca tctaattcat ttaacttttc
    23401 tacaaaattt ttatttaagt cttcaatatt atcattccta tttagtttaa ttgctgctgt
    23461 tctttctgct ggtcctgcaa taagttcaca gctttttata atttcttcac taaaactccc
    23521 atgagtcata actattattc ctatcaccaa tttcacctca cttttcttgt cactttttat
    23581 ataagcaatt gccgtgccaa cttatgtgta tcaataacaa atggctattt tacaggattt
    23641 aatcaaaact ttttactcaa ttttttttaa aaacttatta tttcgatatg tatcaaaaga
    23701 ttttttcaac ctgtatcaaa tctgtatcaa aaaaagtaaa aaaaagatag ccttttggct
    23761 atttttaaat tttgtatcaa cttttgaatt tatctgtatc atattgtgat tcaaatatat
    23821 ctaatatatt tgcatattcc atatctgaaa taattatatc gaatgtctct tctactagct
    23881 taaaactttc ttttataact aaatataatt ctttatttct actaattctt tcttcatatg
    23941 atttataaac taaagactct tttattatta ctctttcaat catacatgaa caatgaaata
    24001 taaactttac taaaagttca tcttgaatta ctaaagaata gtgttcacta attctattaa
    24061 ttacttcttt taatataaaa taagcctttt ccccatttaa aaaagtcaaa gttttactaa
    24121 tattatcaat tagtaatcta tcaaaatatc taccaccatt atctttttca gcatatgtaa
    24181 cttccatatc tccataatgt ttctttatag attctataat attaaaatat aatttctcta
    24241 atgtcatttc tggagttaga gcctttctag ttgcttctat tacaataggt gtacttacca
    24301 tatctattgc ttttacttct tttcctgtag catcacgaat aactttagca aatgttaaaa
    24361 tagaccccat atcagttaaa attaaaattc cctttccttt atcaatttta ttggctattt
    24421 ctacagcttg tactaaaata tcctgaactc tatcttctaa tcccatatta attgccactg
    24481 catggttaca atccagtaaa gtattggcta cattcaccat gctagatgct gtagattcac
    24541 catgcattat gactaatatt gctatactct cctcatttaa tcccacatac gataaataaa
    24601 gaaatgttgc taaaaaaatt gcttcatctt ctggaaactc tactccatac attaatgaca
    24661 tgttagataa tatttctttt gctatgttat attcatatgc tctttccttc ataatttcat
    24721 ctttattagg atgctttact atatttccaa tctttattct ttcaattaaa ttctgaatat
    24781 gtaaagctat agcttttatt aatttatcta atccttctct tttgctccat ttatcatgct
    24841 tttgtaaaat atattttaca gtagttgcaa ttgaatcatt aacaatgttg ttataagctg
    24901 tttgattact actattatat ataaaagtat tcattaaatt ataggaatac ttctgtatgt
    24961 ctccatctat aacacttcta atttgtgact ctttaatacc ttcttgttga agtttattcc
    25021 aagtttcttt tatcattcca taaaaatcta aatcatattt tttattttct attaataaat
    25081 tttcactttc aaaatccttt tcttctggta aaaaaataat atcatctttt ccaataaaac
    25141 tgaaattttg tacaaactcc tcttttctat tatttccata taatgattct ctaatattat
    25201 ttggtagaag agagagcctt acatatacac attccctttt ataggtcata taatctaaaa
    25261 aagctcttgc acaaattaat tgtatatcgc tttttaattg gcctatgttt cccttacact
    25321 tatataaaat aaatgcctta ataacttctt ttgaaacctt taacttaaca ccaatcctaa
    25381 cactctcttc tttaaaaaaa taacatataa gcttcattct ctcttgaaag cctctttcct
    25441 ctaaagacgg aatctttata gttacaggta ttcttcttaa aaacgtttcc aacattgctg
    25501 tttctgggtc ttctgtagtg gctgcaatta tcataactct acactcgtgt accttattag
    25561 cctctcctaa ccttctatat atccctttat ccataagcag aaatagcatt tcttgtccct
    25621 ctgcagataa tctatgaact tcatctaaaa acaatactcc attattagct tcatgtacaa
    25681 taccatactt atctttatca gctccagtaa atgctccttt tacatatcca aaaagctgcg
    25741 ctaataataa ttgctgatta tcagaataat cagcacagtt aaatatgata aatggtgcat
    25801 tatcactatc ttcttttata gttaaactat acttatacat atattctgca aatatagatt
    25861 taccaactcc tgtaggtcct attattaatg tactcaaccc cttaggtgga tatattactg
    25921 ctgctttagc ctgttctatt tgggacctta aacttccatc acatcctact aaattaaaaa
    25981 tattgttctc tttttttata ctctctaaaa tatactcatc tttgatagaa tcattttcac
    26041 tatattcgtt tatagagtta atattatcaa atatcccttt atttagtttc tttcctaaaa
    26101 tactctcaat actttcttta tataagtact gaacaggctt accctttatc tttataataa
    26161 tactttcttt tattaattga tttaattcct tactagcatt acttctattt atacctactt
    26221 cagtagctat atattctgca tcaaatccaa atctaatgcc attattaaag ttcaagtgtt
    26281 cttctgttaa ccttttcaag caaattaaaa ctttttcttt ccttgatagc ttcttttgtg
    26341 tcatagttaa cctcccctat aagcagtaat actgttaaac atttattatt aagcttaatt
    26401 ctacaatatt ttaatatttt tgtctaatta tgtaactatt gattttcttt cctattcgtt
    26461 ttataatata aattacgtta ccctcatctt ttatagagga ggaatttata tgaatttttt
    26521 atcagattta cacacccact ctatagtcag tggtcatggc tatagcactt tactagaaaa
    26581 tattaattat tgtaaagaaa atggaattaa gatactaggt acatctgaac atggtcctaa
    26641 gatgcctggt tctccccaca gatggtactt tcacaacatt caaaatatcc caagaatcat
    26701 aaataacatt ataattttaa gaggctgtga agcaaatata ctagatatta aaggaaacat
    26761 agacctagag ccttttgtaa ttcctcgctt agattatctt attttgtcat ttcacgaagc
    26821 tgtgttttct ccaaatacat tagagaataa tactaaagct ttaataaatg caataaataa
    26881 gcatgataat attgaaatat taggacacct tggaaaccca aactacccaa tcgactatga
    26941 attaatcatt aaattagcta tagaaaagaa tatcttaata gaaataaata attgttctat
    27001 taaaggcgtg tcaagaaatg gtagctcgga taactgtaag tatattgcta cactttgcaa
    27061 aaaatatggt gctaaaatca tactgacttc agatgctcac atttgttttg acataggtaa
    27121 ctatgagtat tctgaaaata tcttaaagga aattaatttt ccagatgaat taataatgaa
    27181 ttatcctaaa aaacttatta atcattttca ccaaaaaggt aaattactag atgttgatta
    27241 tacaaatatc taagtaataa tacatgctta ctttaactcc cataaaaatt ttaatactat
    27301 ttatattata tgaaataaag aaattataat aaagaagcta tttaataaag cttaattact
    27361 tttatgaact tgatggattg atatggtcta tgatagcaat agaaattata acatttttaa
    27421 taaacttagt tttatatacc ttatagtata aatctaaaaa agcatcatct aaaaaggagc
    27481 tgtcacatga gcaaattaaa tttgttctat gatagctctt tttttactta ttttaattag
    27541 gtatattttt aattatttta tataaagctt atgttctaag taaaattatg cataacaaac
    27601 aaaggtataa aaataccatt ttttcagata atatttaatt ataaataata aatttagaat
    27661 acttctttta aatgatgaga gtctagaaat ttttatgtgt attctttaaa taaaaatttc
    27721 cagactctag cccctttttg aatatt
//
LOCUS       DAEPHU010000059        27537 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 01A10CD0081
            SAMN05941466-rid12468953.denovo.059, whole genome shotgun sequence.
ACCESSION   DAEPHU010000059 DAEPHU010000000
VERSION     DAEPHU010000059.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941466
            Sequence Read Archive: SRR6291087
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 27537)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 27537)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068158.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 22:43:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,892
            CDSs (total)                      :: 3,805
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 87
            rRNAs                             :: 8, 1, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 55
            CDSs (without protein)            :: 55
            Pseudo Genes (ambiguous residues) :: 0 of 55
            Pseudo Genes (frameshifted)       :: 21 of 55
            Pseudo Genes (incomplete)         :: 28 of 55
            Pseudo Genes (internal stop)      :: 16 of 55
            Pseudo Genes (multiple problems)  :: 8 of 55
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..27537
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941466-rid12468953.denovo.059"
                     /strain="01A10CD0081"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            complement(<1..292)
                     /locus_tag="KR231_002597"
     CDS             complement(<1..292)
                     /locus_tag="KR231_002597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HBH0004961.1"
                     /translation="MSFKDFLKDKLGFLVYNFTFLIFTVSVIIFSPVDVFLTDTILYI
                     LVVNVVFLFLYLFISYIKKNKFLDKIKNDTFKINMNDIELARCKNEEKIYLNI"
     gene            complement(316..990)
                     /locus_tag="KR231_002598"
     CDS             complement(316..990)
                     /locus_tag="KR231_002598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBH0004962.1"
                     /translation="MFKIMVVEDDVSLKNIIAKCLTKWGHDVHQIENLENIIEEFKNY
                     NPELVLLDINLPFYDGFHWCNEIRKISKVPIIFISSRNSNMDVIMGVNLGADDYIQKP
                     FSVDVLVAKVNALLRRTYNFVDNNSNQIIHNGVTLDLSTATINYEDNTIELTKNEIKI
                     LHELMKYKGQIVSRNKLMKKLWDNDWFVDDNTLTVNVNRIRSKLNEIGLEDFIETKRG
                     LGYIIS"
     gene            1278..2045
                     /locus_tag="KR231_002599"
     CDS             1278..2045
                     /locus_tag="KR231_002599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003722224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH0004963.1"
                     /translation="MEEILSVENIKKEYGRKGSKHEALRGITFKVYKGEFVGIMGSSG
                     AGKSTLLNIISTIDLPSSGDIYINGKNTIKMKQNELADFRRDNLGFVFQDSNLLDTLT
                     IKENIMLPLSLKNERVSVIENRIKEISKELNIESILDKYPGEVSGGQKQRGAVCRAIA
                     TKPSLVLADEPTGALDSKSARDLLNCLLKLNKDSNKTILMVTHDAISASFCNRILFIK
                     DGIIFTEIVKGESNREFYNKIVNTVSLIGGVNKNDFI"
     gene            2032..3969
                     /locus_tag="KR231_002600"
     CDS             2032..3969
                     /locus_tag="KR231_002600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBH0004964.1"
                     /translation="MTLFRIAMQNVKNSFFNYLMYFISIVFSVFVFFSFKSIEYNEAL
                     SSLGEKTRMSINTSSIVIVVFVFLFIYYSNSFFFNRRRREVGTYSLLGMRKNQIGKIF
                     LYETFLMGIVAILIGIFLGLLFSKLMTMMLVKLMNEMIVVNMNLSIKALVQTLAVFLI
                     IFIVIGIRNTIVIRNKRIIELFNKYPEKYKFKKFIKLKCVLGVLLIAISYLMSISYFI
                     AENIMLSVFILVTIIPGTFLFFSSTMYMIIDAVKKRKSFYYKGQNLIAFSELGFKLKS
                     NSSVLAVIAILIATSVTMLGFTISLYYDIDRNISENYKYSYTINLGNSYVNNEIDKLL
                     YKYKKDNKIIFDKIIELIDKDINIEMYYKNRNSYIEDRTSVDIIRESDFKKLRQYQNN
                     NYEELTSKESVYYVSDSYKKIFFKDFEIEKINLHIKDANEYDINLFKVQKSILEPEIN
                     SQATFDLIVVKDDVFNQLKLHGNSRLIRLIDIKNEKKELDLTLKLKNIVSENMKFTYP
                     FNFTSSIESYDNLIKLSGLMLFIGIFLSVVFLLCTGSIILFKQLSNIYDDKERYIMLI
                     KLGANNKDIEKIISKQLKVIFLMPLVVGTVHNLFAMSIAQKFIPRSLLVPIIITLVIY
                     FIGYFIYYFLTLKYALNMIKE"
     gene            4194..5807
                     /gene="ggt"
                     /locus_tag="KR231_002601"
     CDS             4194..5807
                     /gene="ggt"
                     /locus_tag="KR231_002601"
                     /EC_number="2.3.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyltransferase"
                     /protein_id="HBH0004965.1"
                     /translation="MKFNAYQHKYSSIRNVVYAKNGAVATSTPLASQAGLEILKKGGN
                     AVDAAVATAATLAVVEPTSNGIGGDAYALVWIEEEKRLYGLNSSGFAPENMELKNYNN
                     MKEMPKYGFGAVTVPGIPAAWSELNKKYGKLSLMECLSPAINYAREGYVVSPNVAKVW
                     KKSYELYEKELIGEEFKPWFDTFSKDGKAPEAGDIFICEEQASTLEEIANTQAESFYR
                     GRLADKIDEYSKKFNGAIRKSDLECFYPTWVEPISTEYKGYKIFEIPPNGHGITVLMA
                     LNILKELELEGNIENVEDIHKIIESLKLAFADSKTYVTDIEHMKVKIQELLSQEYAKK
                     RSLLIDNKEALYPTAGEPYCGGTVYLCTADKDGNMVSYIQSNYINFGSGIVIPRTGIA
                     LHSRGNNFNLDPKHHNVVKPFKKPYHTIIPGFLGKEDKAIGPFGVMGAFMQPQGHIQV
                     LTNMIDFGLNPQEALDAPRWQWIKGKEIEVEPEMPKHIIDSLIEKGHEIKVIHDTVDM
                     GRGQIIFKTEQESYICGTESRCDGHIAVY"
     gene            complement(5940..6791)
                     /locus_tag="KR231_002602"
     CDS             complement(5940..6791)
                     /locus_tag="KR231_002602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfurtransferase"
                     /protein_id="HBH0004966.1"
                     /translation="MKNIISAKELISKLEKNDNLVVIDCRFDLINRTYGIDSYKKGHI
                     KGSFILDIDKDLSSPTKEHGGKNPLQDPLILKEKLEKMGVDNDTTIVTYDDGDLNGAC
                     RLFFQLKHLGLKNVYVLDGGITSFVKEGGELEEKVNIPSCTGKEIRPNINNGLVVPME
                     YVKSKLYKKDTVIIDCRANERYQGLVEPAYSKAGHIPSAKNYFCKDLIKSDFENGSLK
                     DIEFLKKFFKDLNNYDEVILSCGSGISACVNSLALRELDIPHKIYIGSFSDWISYDDN
                     EIKTGQE"
     gene            7417..8310
                     /locus_tag="KR231_002603"
     CDS             7417..8310
                     /locus_tag="KR231_002603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfide/dihydroorotate dehydrogenase-like
                     FAD/NAD-binding protein"
                     /protein_id="HBH0004967.1"
                     /translation="MSNKIVSKRQLTDSIYLMEIEAPRVAKSSQPGQFIIIKNDEKGE
                     RIPLTIADYDREKGTVTIVFQTVGASTKKLAMFEENDFVMDFVGPLGQASEFIHEDIE
                     ELRNKKILFVAGGVGSAPVYPQVKWFKEHGLDVDVIIGARTKELIILEDDMKKVAKNV
                     YVSTDDGTYGFNGRVTDLLKDLVDNQGKKYDQAIVIGPMIMMKFMCQLTKELNIPTIV
                     SLNTIMIDGTGMCGGCRVSVGNETKFACVDGPEFDGHLVDFDQAMRRQSMYKTQEGRA
                     MLKLEEGDSHHHSNCGCGGNK"
     gene            8310..9704
                     /gene="gltA"
                     /locus_tag="KR231_002604"
     CDS             8310..9704
                     /gene="gltA"
                     /locus_tag="KR231_002604"
                     /EC_number="1.4.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADPH-dependent glutamate synthase"
                     /protein_id="HBH0004968.1"
                     /translation="MDAKKVKVPVREQEPAVRATNFDEVCLGYNKEEAMAEANRCLAC
                     KKPKCVGGCPVGIDIPGFITKIKEDDIEGAAKVIAKSSSLPAVCGRVCPQESQCEGVC
                     ILGIKSDAVSIGKLERFVADWSKENDINLSDTEPKKNQKVAVIGSGPAGLACAGDLAK
                     KGYDVTIFEAMHEPGGVLTYGIPEFRLPKQAVVQPEIDNIRKLGVKIETNVIVGKTIT
                     VDELIEDEGFEAIFIGSGAGLPMFMNIPGENANGVFSANEFLTRVNLMKAYRDDYDTP
                     ISSGKKVAVVGGGNVAMDAARTALRLGSESYIVYRRSEKELPARAEEVHHAKEEGIIF
                     NTLTNPKEILVDENGYVKGMVCIRMELGEPDDSGRRRPIEIEGSEFVLDVDTVIMSLG
                     TSPNPLISSTTKSLDINKKRCLITDENGQTSKEGVFAGGDAVTGAATVISAMGAGKTA
                     AASIDEYLKAKVNA"
     gene            10070..12289
                     /locus_tag="KR231_002605"
     CDS             10070..12289
                     /locus_tag="KR231_002605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EAL domain-containing protein"
                     /protein_id="HBH0004969.1"
                     /translation="MKKREKVFDGLVFKHILILLILLVLIDLTSTIIYASNSMEITSR
                     NMIEASKRELENYLEVNISLLKALSQDDRFSNGETSLIEKGKLLSPYQKEYNLFMIGI
                     TDTKGNASSTYRENVNSIKDKPSFEKAIKTKQVVVSDIEVSNVTGDKVFIIYVPIVKN
                     NEMIGTIFASFYFQDVNNLISRSNFDDSIKFLMIDKDYTIISHPNKKYVNDKSKMLDL
                     EGNIIGTTKSEILKNINKKCQGDFLSWDNWRLYNVKYTNIKWTNWTLVSKCNIFKNFK
                     NLIVNFMIKLYFYIVIFMILWKLSNAKLIEQLKKLAYYDSLSGIKNKEKFRKDSMYIL
                     KNYYQDNFYLVQLDVNKFKYINEMFGYAEGNKILIHISQVLNNNTNKYEICARMDNDH
                     FILLIACNTEDELLNRLSKINKEICNLNTTNSSKYKIVMSSGIYKITKKDDIKKIDLL
                     IDRANIAAKSKKEKYEHSYSFFNEDTRNRLYKEKRLEDNMNKALEKGEFIVYYQPKYS
                     LDDVNEIEGAEALIRWNSPEFGFISPIDFVPLFEKNGFIVNIDMFVFEEVCKTLNKWI
                     NKGYTPVPISVNMSRVHLYRDNFIENITDLISKYNISPEFIELELTESVVFDNLNILI
                     DIMKKIKEIGFLISMDDFGSGYSSLNLLKDLSFDILKLDRGFLIETTDTKRGKIIISK
                     IVEMAKAIDIKVICEGVETYEQVEFLKEIGCDKVQGYLFAKPMVLDEFEKHLNFKFD"
     gene            12436..13182
                     /locus_tag="KR231_002606"
     CDS             12436..13182
                     /locus_tag="KR231_002606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014466367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH0004970.1"
                     /translation="MNILSIRNISKTYCGNIPFKALDKVSLNIEKGEFVSVMGPSGSG
                     KSTLLNIISTVDRQSEGEVVLDGYDVSKLKGEKLAEFRRKQLGFVFQDFNLIDTLTVG
                     ENIMLPLTLEGASIKDMNIQTKSISKFLGIDKILDRKTYEISGGQAQRCAIARAIINK
                     PAILLADEPTGNLDSKSTDDVLKLFTRINKEQKVTTLMVTHEAYSASYSDRVIFIKDG
                     CIYTEIKKSESSNSFYSDILAVLSQIGGVR"
     gene            13182..15062
                     /locus_tag="KR231_002607"
     CDS             13182..15062
                     /locus_tag="KR231_002607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBH0004971.1"
                     /translation="MDFRKFAYNNIVRNFRAYLAYFLSSVFSIMIFFVFAVSMFHPII
                     TKSGMQSGSTAFMALMTSELIIFGFSLLFILYSLGNFLKYRLKDFGVLMIIGMSNRQL
                     KKLILIENLIIGFLAVMLGILLGLSISKLFLLYLSKLFYMNLTEFYFPVKAMLLTIVS
                     FMILFLITGPMSLKLLSKKSILELLVGTKKPKKEIKSSKLFGIIGVICLILGYAMILF
                     GNKLKINGGMYTTALLITLGIFLFFSQFTILILKYLKNKEKFYKNKVNMLLISNLIYK
                     LKDNTRLLFLITILLSATLVAFTTTSTLVSSQGEASKNNFPMVYSYFSEHNNEKEYEE
                     LQQIREAIKGYDYKELSFPVLKYNREVLLSVKNYNKLSKELGLDKISSKLEKYEGIII
                     PSSNSQEHINSLKQLKNYSIKNLNIEVKKSKNKIIFPTGLFSKVVVISDDLYNEVKGE
                     FSKINFHGFDYKNWQSSAKITENLKEKHFNLDREYNRSYFLTLPDMYLVELQQSKILQ
                     FMGVFIGVILFIAVFSFLYFRLYTDEIEDNVKYKKLSKIGLSFKNMNKIVSIEIGTLF
                     FIPYFIAIINSIISLLFLNQVLNNSFKLENLGILLLISSIYSLYFYLLKKNYTRKVWF
                     FD"
     gene            15181..16572
                     /locus_tag="KR231_002608"
     CDS             15181..16572
                     /locus_tag="KR231_002608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HBH0004972.1"
                     /translation="MENQQLLGTERISKLLLKYSIPAIIGMLVNSLYNVVDRIFIGNI
                     PGVGPLAITGLGVTMPIMTIILAFGMLIGIGTTTTISIKLGQGKVEEARKLIGNAMTL
                     SVITGIIIMILGILFANKILTLFGASENTLIYAKSYINIILLGTVVNLLSFSLNHSIR
                     ADGSPKISAGIMIVGCLTNIVLDWILIFGFNLGIQGAAIATVTSQALTAILTIGYYIS
                     GKSNLRFSKSNLKLDKKLIKAVFAIGMSPFAMQLAASLVQVISNIALKTHGGDLAIGA
                     MATISSIAMVFLMPIFGINQGAQPIIGFNYGAEKYDRVKKAYLGSLVVATIILCMGMV
                     VVMLFPEAIIGIFNKDPELMNISVNGLRIYLLMLPIVGLSVTGTNFIQSIGKAKMAML
                     LSLLRQVILLIPAVLILPTFLGLQGVWTAQPVSDFIATVITGIVVFRELKRYTPKTEK
                     LNENERLNEITTE"
     gene            16679..17719
                     /locus_tag="KR231_002609"
     CDS             16679..17719
                     /locus_tag="KR231_002609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436700.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fic family protein"
                     /protein_id="HBH0004973.1"
                     /translation="MEFTKKSKLKNMYVNMNVARMLSKINEYKGRQLLYKKQPKEILE
                     NLEKKSLVDCSESTYIGNQRDSSNFNLEKLISNEVTPRSREELSIVEYRDVVKTINSA
                     YESIPISSQTILELHGYLYKFSSTRGGSYKSDNDFIEHNLKPSEFISTDSSVNKVEKA
                     VEEICEAYNTLIEEDEIDILILISAFVLDFILIHPFKEGNIKMARVLILLLLNKNGYE
                     VGRYISLGKIFDDSSYEYYSNLNYLKASIGSEKADMNAWIEYFLETILTAYEKLDDSL
                     NISDKKRQTKTSRIEKIINSTLGYFTKEDIRDLCPDIPEPTINRVFNNLRKQDKIEVV
                     ARGRSAKWKKKY"
     gene            18208..18861
                     /locus_tag="KR231_002610"
     CDS             18208..18861
                     /locus_tag="KR231_002610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HBH0004974.1"
                     /translation="MKKKLLYINVNSKPEDLSSSKTVARKFINKFMEKNKDFEVEEID
                     LYKEHIPRLEYQYFEKRNSIVSEENAKNLDDKDRKELTKIRNLCDQFVNASVYVIAAP
                     MWSLSFPAPLKEYIDCIIQDGKTISFEGNDKPQGILNDIDRSMVYIQSSGGHIPWVLK
                     PVMNKGLNYVESIMKFIGIKKFDELLVDGTGTSEEERQAAIEKASEKIDGIIDGMKF"
     gene            18937..19146
                     /locus_tag="KR231_002611"
     CDS             18937..19146
                     /locus_tag="KR231_002611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0004975.1"
                     /translation="MREEKSNEKYDCYWCNQENNFCVEIKDNIVMIDDGTGTLKQAVF
                     IGYKQIQINLNCSHCQNLNRIKLNL"
     gene            complement(19286..19852)
                     /locus_tag="KR231_002612"
     CDS             complement(19286..19852)
                     /locus_tag="KR231_002612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1836 domain-containing protein"
                     /protein_id="HBH0004976.1"
                     /translation="MMNNELNTIILETLNNADITSNDIPSIDLYMDQIISLIDNKLSA
                     NKRFESDKILTKTMINNYSKEGLIKPVKGKKYTKEQILQMIIIYSMKNTLTIQEIKRI
                     LHGVYEKDNFSEKDLVSCYEKFMLIKENQRKNIPDFIESNFENISINPENKDDLLIAL
                     LSLTSMADQLKNISEKLVDRYFPDITKK"
     gene            20013..20666
                     /locus_tag="KR231_002613"
     CDS             20013..20666
                     /locus_tag="KR231_002613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin III family protein"
                     /protein_id="HBH0004977.1"
                     /translation="MYQFFLKGRDPISSLTHFIGACLSLLATIILVFQSVTLQETSLL
                     MIVSVSVFGLSLIALYSASSYYHFLKGTPEQELFFRKVDHAMIYVLIAGSYTPICLNF
                     MEKKEGIIFVTAIWIVAFIGIIIKIFWMDAPRWLSTSIYLLMGWAIVFDINAFNSIPK
                     DCLRLLIMEGVSYSIGAIIYIIKKPNISPEFGFHEIFHIFIMIGSLFHFLAVLLYVL"
     gene            complement(20824..21000)
                     /locus_tag="KR231_002614"
     CDS             complement(20824..21000)
                     /locus_tag="KR231_002614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0004978.1"
                     /translation="MYKYDDYVNLTNDLDLPVEIRNKCVRIVSVSENLEDIIIVHKFK
                     LYVVNEKYIKGIME"
     gene            21528..22472
                     /locus_tag="KR231_002615"
     CDS             21528..22472
                     /locus_tag="KR231_002615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP phosphoribosyltransferase regulatory
                     subunit"
                     /protein_id="HBH0004979.1"
                     /translation="MKFLRIEDEVIYSKKRYKLKREIDKLFLDEEYFQIEPQLFEEYD
                     EFTTINNKIPEESMVKVVNGKVMVLRADITTSIIKSLVPRWEDGLKLKLFYNSSIYKN
                     KNTVGIKEIRQIGCEYLGEASVEADREVVKLALKILEKYNNNFILEVGSSKYIHGLLE
                     ELNLNKNCENQIKNLLYTKNTHELKVYIEELKIKREVKELLSNILSLQGNLYNVIEKS
                     NKFYCNNKMKQALEELKQVNNLIEECNFLDKARFDLSMITMLDYYEGIMFRGYYPNSY
                     KEILSGGRYDSLTKEYGKEIPAIGFTLSVDELMKYVYK"
     gene            22494..23120
                     /locus_tag="KR231_002616"
     CDS             22494..23120
                     /locus_tag="KR231_002616"
                     /EC_number="2.4.2.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP phosphoribosyltransferase"
                     /protein_id="HBH0004980.1"
                     /translation="MDYLTIALAKGRIEGESFKKFKKMGLGDSIDTDTRKLIFKDEEN
                     KIIYIHVKPSDVVTYVEKGVADLGIAGKDTILENETDVYEIYDLGFGKCKFAVAGLKG
                     DSIYREDEYLKVATKYPNIAKKYFKEKGQKIEIIKLNGSVELAPIVGLSDVIVDIVET
                     GNTLKANGLEILEDICNISARIISNRASYRFKYEQIQNIIRLFEELDN"
     gene            23154..24203
                     /gene="hisC"
                     /locus_tag="KR231_002617"
     CDS             23154..24203
                     /gene="hisC"
                     /locus_tag="KR231_002617"
                     /EC_number="2.6.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidinol-phosphate transaminase"
                     /protein_id="HBH0004981.1"
                     /translation="MREKESIRELKGYEPNHVNCKVKLDANEGSKRLFKYLIKEISDS
                     DIDLNLYPEDSYSDLKESIIDYINISGVNKKNLLVGNGSSEIIDLIIHTFVDKDEVIL
                     SFSPSFSMYSIYSQINGSKFIGVESDENLVINIDNVIEKVKENNPKIVIVCNPNNPTG
                     TILKREEIIKLLDSTNSLVVLDEAYMDFGEESMLSDVFKYDNLIVLRTLSKAFGLAGI
                     RTGYMLSNSSLINSVEKVRPPYNLNSLSDFIATRALRNKDVVKAYIKEVKEEREVLYK
                     EMIGMGIKAYKSQANFILFYSEIENLSQKLIDRGVLIRKFGGKLENYYRVTIGDKEEN
                     SMFVGAIRDILKKEK"
     gene            24206..24784
                     /gene="hisB"
                     /locus_tag="KR231_002618"
     CDS             24206..24784
                     /gene="hisB"
                     /locus_tag="KR231_002618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="imidazoleglycerol-phosphate dehydratase HisB"
                     /protein_id="HBH0004982.1"
                     /translation="MRIWKVERNTLETQILVELNIDGSGKAEIDTGIGFLDHMLTLMS
                     FHGKFDLKVICKGDTYVDDHHSVEDIGIAIGEAFKNALGDKKGIRRYSNIYIPMDESL
                     SMVAIDISNRPYLVFNAKFDTQMIGSMSTQCFKEFFRAFVNESRVTLHINLLYGENDH
                     HKIESIFKAFARALKEGSEIVSNEIASSKGVL"
     gene            24786..25391
                     /gene="hisH"
                     /locus_tag="KR231_002619"
     CDS             24786..25391
                     /gene="hisH"
                     /locus_tag="KR231_002619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="imidazole glycerol phosphate synthase subunit
                     HisH"
                     /protein_id="HBH0004983.1"
                     /translation="MNIIVDYGLGNIDSVSRGFRKAGIETKISSDIDEIKQADSLILP
                     GVGAFRDSISALDKLGLIPIIKEHVSKGKFMIGICLGMQLLYEKSYEYGEYEGLGLIK
                     GSIDKLDISLKVPHMGWNNLKFNKANDDILKYINEDDYVYFVHSYYANSSNEELIAFS
                     EYEKKIPAIVRKGNVYGIQFHPEKSGEVGLNILRAYGEMIK"
     gene            25388..26110
                     /gene="hisA"
                     /locus_tag="KR231_002620"
     CDS             25388..26110
                     /gene="hisA"
                     /locus_tag="KR231_002620"
                     /EC_number="5.3.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-(5-phosphoribosyl)-5-[(5-
                     phosphoribosylamino)methylideneamino]imidazole-4-
                     carboxamide isomerase"
                     /protein_id="HBH0004984.1"
                     /translation="MIIFPAIDIKDNKCVRLTQGEFDKVNVYYDNPLEVAYKWKNEGA
                     EYIHIVDLNGARSEFGVNTKIIEDIANNIDIPIQVGGGVRDKEKVKSLINAGVTRVIL
                     GSIAIENLNLVEELVNEYKEKIVVSIDAKDGKVAVRGWEVVSNVDSLTLCKQLEKIGV
                     QTIVYTDISKDGMLQGPNFDIYERIAKETSLNVIASGGVTSIEDVKRLKAMNLYGAII
                     GKALYDKKIDFKEAQQLCLLGE"
     gene            26092..26850
                     /gene="hisF"
                     /locus_tag="KR231_002621"
     CDS             26092..26850
                     /gene="hisF"
                     /locus_tag="KR231_002621"
                     /EC_number="4.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000880088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="imidazole glycerol phosphate synthase subunit
                     HisF"
                     /protein_id="HBH0004985.1"
                     /translation="MLTRRIIPCLDVRNGRVVKGKKFKDIVDVDSPEVLGKFYSDCGA
                     DELVFYDITASNEERKTSLEFVTKVAENINIPFCVGGGVNKLEDFTDILRKGADKVSI
                     NSSAVKNPELIREASLKFGAQCVVLSIDAKKNEEGSWSVYVKGGREKTNLDAIEWAVK
                     GVELGAGEIVVNSMDEDGMKNGYDIELLSKITSLVNVPVIASGGAGKKEDFYEAVNKS
                     NVDGILAASVFHFGEIKINDLKKYLKDMGVEVRL"
     gene            26878..>27537
                     /locus_tag="KR231_002622"
     CDS             26878..>27537
                     /locus_tag="KR231_002622"
                     /EC_number="3.5.4.19"
                     /EC_number="3.6.1.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional phosphoribosyl-AMP
                     cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE"
                     /protein_id="HBH0004986.1"
                     /translation="MDNKCNNVYSDEVEKFIRSIKFDDKGLVPVVVQEVVSKDVLMLA
                     YMNKDAIKKTLKDKVACYFSRSRQELWVKGETSGNTQKVVKMSYDCDVDTILLFVEQT
                     GVACHTGNYSCFYRDLFDDSSKMELEVQTNILKELYDLINERKNNPVEGSYTNYLFEK
                     GIDKILKKVGEESSEVIIASKNTDKSELIYEISDLVYHTLVLMIEKGVEIDEIKKELL
                     KR"
BASE COUNT        10863 a         2758 c         4655 g         9261 t
ORIGIN      
        1 taatgttcaa gtatattttt tcttcatttt tacatctagc taattctata tcattcatat
       61 taattttgaa tgtatcattt tttatcttat ctaaaaattt gttcttcttg atgtagctaa
      121 taaatagata taaaaataaa aacacaacat ttacaactaa tatatataaa atagtatcag
      181 tcagaaaaac atctacagga gaaaatataa taactgatac tgtaaaaatt aagaaagtaa
      241 aattgtatac taaaaaacct agtttatcct tgagaaaatc tttaaagctc ataaattcac
      301 ctacttagaa ttgttttaac tgattatata acccaatcct ctttttgttt ctataaaatc
      361 ttctaaacca atttcattta attttgagcg tattctattt acattgacag ttaatgtatt
      421 atcatctaca aaccaatcat tatcccataa ttttttcatg agtttattcc tacttactat
      481 ctgcccctta tatttcataa gctcatggag aattttgatt tcattttttg ttagctcaat
      541 agtattatct tcatagttta ttgttgcagt tgataaatct aaagtaacac cattgtgaat
      601 aatctgattt gagttattat caacaaaatt ataagttctt cttaaaaggg cattaacttt
      661 agctactaag acatctacag aaaaaggttt ttgtatataa tcatctgcac ctaaatttac
      721 acccattatt acatccatat tagaatttct tgaagaaata aaaattatag gaacttttga
      781 aatttttctt atttcattac accaatgaaa accatcataa aatggaaggt ttatgtccaa
      841 taaaactaat tctgggttat agtttttgaa ctcttctatt atattttcaa gattttctat
      901 ttgatgaaca tcatgtcccc atttagtaag acactttgct atgatatttt tcaatgagac
      961 gtcatcttca actaccatta ttttaaacat tcttacctcc taattcaaaa tagttatatt
     1021 aacataacta tattctactt gataaattaa aatatttcta ccttattacc taaaataatt
     1081 atattaatat aactatattt tacttgataa attatatttt aaacataatt gcaataaatt
     1141 tgaagaaata taattaatac ttacgaaaat gtaaccttaa attaatataa ttaaatgttt
     1201 aaaagccatt ttaatatata taatatattt gtgagaattg ataaataact aattgtgatg
     1261 aaaggtgatt attaactatg gaagaaatat tatctgttga aaatataaaa aaggagtatg
     1321 gaagaaaagg ttcaaaacat gaagctctaa gaggaataac tttcaaggtt tataaaggag
     1381 aatttgttgg tattatgggg tcttccggtg ctggtaaatc aacactttta aatattattt
     1441 ctacaataga tttaccttca tcaggagata tttatataaa tggaaagaat actattaaaa
     1501 tgaagcaaaa tgaattggca gattttagac gtgataatct aggctttgta tttcaagatt
     1561 ctaatctttt ggatacactt acaataaaag aaaatataat gttgcctctt tctttaaaaa
     1621 atgaaagagt atcagtaata gaaaatagaa taaaagagat ttcaaaagaa ttaaatatag
     1681 aatctatatt agataaatac cctggcgaag tttctggtgg acaaaagcaa agaggagctg
     1741 tatgtagagc tatagcaaca aaaccatcat tagtacttgc agatgagcct acaggagcat
     1801 tagattctaa atctgctagg gatttgttga attgtctatt aaaattaaac aaagacagca
     1861 ataaaacaat attgatggta actcatgatg ctataagtgc gagtttttgc aatagaatac
     1921 tctttataaa ggatggaata atattcacag aaattgtaaa gggagaaagt aacagagagt
     1981 tctataataa aatagtaaat acagtttcct taattggagg agttaataaa aatgacttta
     2041 tttagaattg caatgcaaaa tgtaaagaat agttttttta attatttaat gtactttatt
     2101 tcaattgtat ttagtgtatt tgtatttttt agttttaaat ctatagagta taatgaagcg
     2161 ttgagttcac ttggagagaa aactaggatg agtattaata caagttcaat tgtaatagtg
     2221 gtatttgtat ttttatttat atattattca aactcatttt ttttcaatag acgtaggcga
     2281 gaagtaggaa cttatagttt acttggaatg aggaaaaatc agataggaaa aatattttta
     2341 tatgaaactt ttttgatggg tatagttgca atactaatag gtatattttt aggactgtta
     2401 ttttcaaagc ttatgactat gatgcttgta aaattaatga atgaaatgat agtagtaaat
     2461 atgaacttaa gtataaaggc cttagttcag acactagcgg tatttttaat aatattcata
     2521 gttattggaa taagaaatac tatagttatc agaaataaga gaattataga gttatttaat
     2581 aaatatccag aaaaatataa gtttaaaaaa tttataaagt taaaatgtgt acttggtgtt
     2641 ttattaatag ctatttctta tttaatgtca attagttatt ttattgctga aaatattatg
     2701 ctttcagttt ttatattagt tacaataata cctggaactt ttttattttt ttcatcaact
     2761 atgtatatga ttattgatgc tgttaagaag agaaaaagtt tttattataa gggacagaat
     2821 ttaattgcat tttctgaact tggatttaaa ttaaagagca atagtagtgt attggctgta
     2881 atagcaatat taatagctac aagtgtaact atgctagggt ttaccatatc actttattac
     2941 gatatagata ggaacataag tgaaaattat aaatacagtt ataccataaa tttaggaaat
     3001 tcttatgtaa ataacgaaat tgacaaatta ttatataaat ataaaaaaga taataagata
     3061 atctttgata aaataataga acttatagac aaagatataa atattgaaat gtattataaa
     3121 aatcgaaata gttatataga agatagaacg tctgtagata ttattagaga aagtgatttt
     3181 aaaaaattaa gacaatatca gaataacaat tatgaagaat taacttcaaa ggaatctgtg
     3241 tactatgttt ctgattcata caaaaaaata ttttttaaag actttgagat tgaaaaaata
     3301 aacttgcata ttaaagatgc aaatgagtat gatataaatc tgtttaaagt acaaaaaagc
     3361 atcttggagc cagaaataaa ttcacaagct acgtttgatt taattgtagt aaaagatgac
     3421 gtatttaatc agttaaaatt acatggaaat tctagattaa taagattaat tgatataaaa
     3481 aatgaaaaaa aagaactgga tttgacttta aaattaaaaa atatagtaag tgaaaatatg
     3541 aaatttactt atccttttaa ttttacatca agtattgaaa gttatgataa cttgataaaa
     3601 ttaagtggtc taatgctgtt tataggcata tttttgtctg tagtatttct tttatgtaca
     3661 ggtagtataa tcttatttaa acaattatca aatatatatg atgataagga aagatatatt
     3721 atgttaataa aacttggagc aaataataaa gatattgaga aaataatatc aaaacagtta
     3781 aaagttatat ttttaatgcc attagttgta ggtacagttc ataatttatt tgctatgtct
     3841 atagcacaaa agtttatacc aaggtcatta cttgtaccaa ttatcataac tctagtcatt
     3901 tattttatag gatattttat atattatttt ttaactttaa aatatgctct aaacatgata
     3961 aaagaataaa ttatttttaa gttaaaagaa ttagatatat gttttgaata aaataactta
     4021 tttaagtgca gatagaaaat actagaattg agtttaagat atttatttaa agataaaatt
     4081 aaagttagga aaaagtctat attttatatc attttgtatc agttacatta attgatgtta
     4141 tataataaat ctaagcagaa tatcaaataa aaaatgacga ggagctgaaa tttatgaagt
     4201 ttaatgccta ccaacataaa tactcatcaa taagaaatgt cgtgtatgct aaaaatggag
     4261 cagttgcaac atcaacacca ttagcatctc aagctggact tgaaatacta aaaaagggtg
     4321 gaaatgctgt tgatgcagca gttgcaacag ccgccacatt agcagtagta gaacctacaa
     4381 gcaatgggat tggaggagat gcatatgccc ttgtttggat agaggaagaa aaacgattgt
     4441 atggtttaaa ttctagtggc tttgctccag aaaatatgga attaaaaaat tataataata
     4501 tgaaagaaat gccaaaatat gggtttggag cagtaactgt acctggaata ccagcagctt
     4561 ggtcagaatt aaataaaaaa tatggtaaac ttagcttaat ggaatgctta tctccagcga
     4621 taaactatgc aagagaggga tacgtagtat ctcctaatgt agctaaggta tggaaaaaat
     4681 catatgaact ctatgaaaaa gaacttattg gagaagagtt caaaccatgg tttgatacat
     4741 tttctaaaga tggtaaagct ccagaggctg gagatatatt tatatgtgaa gaacaggcaa
     4801 gtacattaga agagatagca aatactcagg ctgaaagctt ttatagagga agacttgctg
     4861 ataaaataga tgaatattct aaaaaattta atggggctat aagaaagagt gacttagagt
     4921 gtttttatcc aacatgggta gaacctataa gtacagaata taagggatat aaaatatttg
     4981 aaatcccacc aaatggtcat ggaataacag ttttaatggc acttaacata ttaaaagaat
     5041 tggaattaga aggaaatata gaaaatgtag aagacataca taaaattata gagagtttaa
     5101 aattagcttt tgcagattct aaaacatatg taactgatat agagcatatg aaggtaaaga
     5161 ttcaggaatt actaagccaa gagtatgcta aaaaaagaag tttattgatt gacaataaag
     5221 aggctttgta tccaactgca ggagagccat attgtggtgg tacagtatac ctttgtactg
     5281 cagataagga tggaaatatg gtttcatata tacagagcaa ttacataaat tttggttcag
     5341 gaattgtgat accaagaact gggattgctt tacatagtag aggaaataat tttaatttag
     5401 accctaaaca ccacaatgta gtaaaaccat ttaaaaaacc ttatcatact ataatacctg
     5461 gatttttagg taaagaagat aaagcaatag gtccatttgg tgtaatggga gcttttatgc
     5521 aaccacaagg acatattcaa gtgttaacaa atatgattga ttttggatta aatccacaag
     5581 aggcgctaga tgctccaaga tggcagtgga taaaaggaaa ggaaatagaa gttgaaccag
     5641 agatgccaaa gcacataata gattcattaa ttgaaaaggg tcatgaaata aaagtaattc
     5701 atgatactgt cgacatggga cgaggtcaaa taatatttaa aacagaacag gaaagttata
     5761 tttgtgggac ggaatcaaga tgtgatggtc atattgcagt ttattaatat tatcaactaa
     5821 aatatatata ataaatttaa agagtatatg aaataattag taaaggcgaa agtctacaat
     5881 gactgacgcc tttacaaaat ttaagctatc atatgctgat tttatataga ttatgagcct
     5941 tattcttgac cagttttgat ttcattgtca tcataactaa tccagtcact aaagctacca
     6001 atataaatct tgtgaggtat atccagttct ctaagagcaa gactgttaac acaagcagat
     6061 atccctgaac cacaagataa aattacttca tcataattat ttaaatcttt aaagaatttt
     6121 tttaaaaatt ctatatcttt aagtgagcca ttttcaaagt cactttttat taaatcctta
     6181 caaaaataat tttttgcact tggtatatga ccagcttttg agtaagcagg ttcaactaaa
     6241 ccctggtatc tctcattagc acggcaatct attattacag tatctttttt gtataattta
     6301 gacttaacat attccattgg aacaactaaa ccattgttta tatttggtct aatttcctta
     6361 cctgtacaac ttggtatatt cactttctct tccaattctc caccttcctt tacgaaagat
     6421 gttattcccc catccagtac atagacattt ttaagcccca aatgttttaa ttggaaaaat
     6481 aatctgcaag ctccatttaa atctccatca tcataagtta caatcgtagt gtcgttatca
     6541 acacccattt tttctaattt ttcttttagt attaaagggt cttgtaaagg atttttacca
     6601 ccatgttctt ttgtaggaga tgataaatcc ttgtctatat ctaagataaa gctgcctttg
     6661 atgtgtcctt ttttataaga atcaatacca taagttctat tgataagatc aaatctgcaa
     6721 tctattacaa ctagattatc atttttttct agttttgata taagttcttt tgctgaaata
     6781 atgtttttca aagaatgtac ctcctgtgtt tatattatct ttattttaat ttatattaat
     6841 tattaacttt ataaactaat attattataa tttattacat aagtaaataa atctttagaa
     6901 attgtaaaaa ttttatataa aaattcaaat aattaatgaa tattgaaaat tttagatata
     6961 taataaaata agagtatatt ttatacaata tgaaagctgg tattgcaata gattaaagcc
     7021 ttatacacgt ttagttttta aagaaattag tgttattatg aaaacctaag ttaatttatt
     7081 aaataaataa ttgaataaaa aaattttatt atgtatttat aaaatttttg ttacaaattt
     7141 ggcataatat agtatacttt aagtgtgtat taggttaaat ctataacaaa ttagacgtat
     7201 gatatagact tagtgtttat tggcatttac aagaaatttg ttaatatcaa ctatttgtag
     7261 tttgggcagt tataattatt atagggggga tgtccaatac aaaacaatca accaagaact
     7321 aatattatat tataaagagt tatagttttg tgtgtttatg tttttaatta aatttaaagt
     7381 gggaaaaata tatttgttag aatggagaat agcgagatga gtaataaaat agttagtaag
     7441 agacaattaa cagatagtat ttatttaatg gaaatagagg cacctagagt tgcaaaatct
     7501 tctcaaccag gtcaatttat aataattaaa aatgatgaaa aaggagagag gattcctctt
     7561 acaatagctg actatgatag agaaaaagga acagtaacta ttgtattcca aacagttggt
     7621 gcttcaacta aaaagttagc aatgtttgaa gaaaacgatt ttgtaatgga ttttgtaggg
     7681 ccattaggac aagcaagtga atttatacat gaagatatag aagaattaag aaataaaaag
     7741 atattatttg tagctggtgg agttggttct gctccagttt atccacaagt taaatggttt
     7801 aaagagcatg gattagatgt agatgtaata attggtgcaa gaactaaaga attaattata
     7861 ttagaagatg atatgaaaaa agtagctaaa aatgtatatg tatcaacaga tgatggtaca
     7921 tatggattta atggaagagt tacagaccta ttaaaagatt tagttgataa tcaaggtaaa
     7981 aaatacgacc aagcaatagt aattggacca atgataatga tgaaatttat gtgccaatta
     8041 actaaagaac taaatatacc tactatagta agtttaaata caataatgat agatggaaca
     8101 ggtatgtgtg gtggttgtag agttagtgtt ggaaatgaaa ctaagtttgc atgtgtagat
     8161 ggtcctgaat ttgatggtca tttagttgat tttgatcaag caatgagaag acagtctatg
     8221 tacaagactc aagagggaag agctatgcta aaacttgaag aaggcgatag tcatcatcat
     8281 agtaattgtg gatgtggagg taacaaataa tggatgctaa aaaagtaaaa gtaccagtta
     8341 gagaacaaga acctgctgtg agagcaacaa attttgatga agtatgctta gggtataata
     8401 aagaagaagc tatggcagaa gctaatagat gtttggcttg taaaaaacca aaatgtgtgg
     8461 gtggatgtcc agtaggaatc gacataccag ggtttataac aaaaattaaa gaagatgata
     8521 tagaaggtgc tgctaaagta atagctaaga gcagttcatt accagctgtt tgtggtagag
     8581 tatgcccaca agaaagtcaa tgtgaaggtg tatgtatact tggaataaaa tcagatgctg
     8641 tatcaatagg taaattagaa agatttgtag cagattggtc aaaagaaaat gacataaatt
     8701 tatctgatac agagcctaag aaaaatcaaa aagtagcagt aataggaagt ggtccagcag
     8761 gtctagcttg tgctggtgat ttagctaaaa aaggctatga tgtaacaatc tttgaagcaa
     8821 tgcatgagcc aggtggagtt ttaacttacg gaatacctga gtttagactt ccaaaacaag
     8881 ctgttgttca acctgaaata gacaatataa gaaaattagg tgtaaaaata gaaactaatg
     8941 taattgttgg taaaacaatt acagtagatg aacttataga agatgaagga tttgaagcta
     9001 tattcatagg ttcaggagct ggtcttccaa tgtttatgaa tataccaggg gaaaatgcaa
     9061 atggagtatt ttctgcaaat gagtttttaa ctagagtaaa cttaatgaag gcttatagag
     9121 atgattatga tacacctatt agttctggta aaaaagttgc tgtagtaggt ggtggaaatg
     9181 ttgctatgga cgctgctaga actgcattaa gattaggttc agaatcatat atagtttata
     9241 gaagaagtga aaaagagctt ccagcaagag ctgaagaagt tcatcatgca aaagaagaag
     9301 gcattatatt taatacatta acaaatccta aggaaatttt agtagatgaa aatggatatg
     9361 ttaaaggtat ggtttgtata agaatggaat taggagagcc agatgattct ggaagaagaa
     9421 gacctataga aatagaaggt tctgaatttg tacttgatgt agacacagtt ataatgtcac
     9481 ttggaacaag cccaaatcca ctaatatctt ctacaacaaa gagtcttgat ataaataaga
     9541 agagatgctt aataacagat gaaaatggtc agacttctaa agagggtgta tttgcaggtg
     9601 gagatgctgt tactggagca gcaacagtaa tatctgcaat gggtgctggt aaaacagcag
     9661 cagcatcaat agatgaatat ttaaaagcaa aagttaatgc ttaatttgta aattaaagag
     9721 agggtgtctc aaaatgaact ttttagttca tgaggcactc tttttgtaca aaatcaaata
     9781 tgttttaatc atttcaacaa tgaaaatttc attcctgtag aaagtctaac ttttaggtct
     9841 tagtacaatc tctattttga tgtagccact tttttagatg gtttaataat ttatcagtta
     9901 ttattgtaat atttgatact aagtaacata actttgtcta actatgataa aatagttata
     9961 caataaaggt cttgtaagga gtgaataatg tgtggctaat aaaatcagat ttgtcaaatc
    10021 taacattaaa taatagaaaa ataaattgtg taattaatgg tattttaata tgaaaaaaag
    10081 agaaaaagta tttgatgggc tagtttttaa gcatatatta atcttattaa tactattagt
    10141 tttgattgat ttaacaagta ccatcatata tgcaagtaac tctatggaaa ttacttctag
    10201 aaatatgatt gaggcatcaa aaagagaact tgaaaactat ttagaagtaa acatatcttt
    10261 attaaaagct cttagtcaag atgatagatt ttctaatggt gaaacatcac taattgaaaa
    10321 gggaaaatta ttaagtccat atcaaaagga atataatctt tttatgattg gtataacaga
    10381 tacaaaagga aatgcttcaa gtacatatag ggaaaatgtt aactcaataa aagataagcc
    10441 tagttttgag aaagcaatta aaacaaagca agtagtagtt tcagatattg aagtcagtaa
    10501 tgtaacaggt gacaaagtat ttatcatata tgtaccaatt gtaaaaaata atgagatgat
    10561 tgggaccatt tttgcttctt tttattttca agatgtaaat aatttaataa gtagaagcaa
    10621 ttttgatgat tctattaaat ttctaatgat agataaagat tatactatta tttctcatcc
    10681 aaacaaaaaa tatgtaaatg ataaaagtaa gatgcttgat ttagaaggga atattatagg
    10741 aaccactaaa agtgaaatct taaaaaatat aaataaaaaa tgtcaaggtg attttttatc
    10801 ttgggataat tggagattat ataatgtaaa atatacgaac ataaagtgga ctaattggac
    10861 tttagtatca aaatgtaata tatttaagaa ctttaaaaat ctaatagtta attttatgat
    10921 aaagttgtat ttttatatag taatatttat gatattgtgg aaattaagta atgctaaatt
    10981 aatagaacaa cttaaaaaat tggcttatta tgattcttta agtggaataa aaaataaaga
    11041 aaagtttaga aaagattcta tgtatatttt aaagaattat tatcaagata atttttactt
    11101 agtacaattg gatgtcaata aatttaaata tataaatgag atgtttggat atgctgaagg
    11161 gaataagata ttaattcata tatcacaggt tttaaataat aatacaaata aatatgaaat
    11221 ttgtgctagg atggataatg accattttat attgttgatt gcttgtaaca ctgaagatga
    11281 acttttaaat agattatcta aaataaataa agaaatttgt aacttaaata ctactaactc
    11341 atctaagtat aaaattgtta tgtcaagtgg aatatataag attactaaaa aggatgatat
    11401 taaaaagatt gacttgttaa ttgatagagc aaatattgca gcaaaaagta aaaaggaaaa
    11461 atatgaacat tcatattcat tttttaatga agatacaaga aatcgattgt acaaggaaaa
    11521 acgattggaa gataatatga ataaagcttt agaaaaaggt gaatttatag tatattatca
    11581 acctaagtat agtttagatg atgtaaatga aattgaagga gcagaagcct tgataagatg
    11641 gaatagtcca gaatttgggt ttatttcacc tatagatttt gtacctttat ttgaaaagaa
    11701 tggttttatt gtaaatattg atatgttcgt gtttgaagaa gtatgcaaaa cattaaacaa
    11761 gtggataaat aaagggtata ctcctgtacc aatctctgta aatatgtcta gagttcattt
    11821 atatagggat aattttatag aaaatataac tgatttgata agtaaataca atatatctcc
    11881 tgagtttatt gagcttgaac taacagaaag tgttgtgttt gataatttaa atatattgat
    11941 tgatataatg aaaaagatta aagagatagg attccttata tcaatggatg attttggttc
    12001 gggatattca tctttaaatc tgttaaaaga cctttctttt gatattttaa aattagatag
    12061 aggattttta atcgaaacaa cagatacaaa acgtggaaaa attattattt ctaagattgt
    12121 ggaaatggca aaagcgattg atattaaagt aatctgtgag ggcgtagaaa cttatgaaca
    12181 agtagagttc ttgaaagaga taggttgtga taaggttcaa ggatacttat ttgctaaacc
    12241 tatggtatta gatgaatttg aaaaacactt aaactttaaa tttgattaat cattaataat
    12301 tattagacta taagataccc taacaactta cttacaaata tgtaagttaa ttgttagggt
    12361 atttttatgg ttaaagtagt atattcacga tattatggta ttgtagtaaa aataaaaaat
    12421 tatggagaat ataaaatgaa catattgagt attagaaata tatcaaaaac atattgtgga
    12481 aatattccat ttaaagcatt agataaggtt agtctaaata tagaaaaggg agaatttgtg
    12541 tctgttatgg gaccatctgg aagtggtaaa tctactcttt taaatataat atctacagtt
    12601 gatagacaga gtgaaggtga ggttgtatta gatggatatg atgtaagtaa attgaaagga
    12661 gaaaaacttg ctgaatttag aaggaaacaa cttggttttg tatttcagga ttttaatttg
    12721 attgacactt taactgttgg cgaaaatatt atgttgccac ttacactaga gggggcaagt
    12781 atcaaagata tgaatataca aactaaaagt atatctaaat ttttaggaat agataaaatt
    12841 ttagatagaa aaacctatga aatttcagga ggtcaagctc aaaggtgtgc tattgctaga
    12901 gctattataa ataaacctgc catacttctt gcagatgagc caactggaaa tcttgattca
    12961 aaatctactg atgatgtttt gaaattattt actaggataa acaaagaaca aaaggtaaca
    13021 acacttatgg taactcatga agcatatagt gcaagttatt cagatagagt aatttttata
    13081 aaagatggtt gtatatatac agaaataaaa aaatctgaaa gcagtaattc tttctattct
    13141 gatatactag ctgttttgtc tcaaatagga ggtgtaagat agtggatttt agaaagtttg
    13201 cttataataa tatagttaga aatttcaggg catatttagc atatttttta agttctgttt
    13261 tttctataat gatatttttt gtttttgcag tgtctatgtt ccatccaatt ataacaaaat
    13321 ctggaatgca gagtggttct actgcattta tggctcttat gacttcagaa ttaataatat
    13381 tcggttttag tctacttttt atattgtact ctttaggaaa tttcttaaaa tatagattga
    13441 aagattttgg agtattgatg ataattggaa tgagtaacag acaactgaaa aaattgatat
    13501 taattgaaaa tttgataata ggatttttag cagtgatgtt aggaatatta cttggtttat
    13561 caatttcaaa attgttttta ttgtatttaa gcaaactgtt ttatatgaat ttaactgaat
    13621 tttattttcc agtaaaagca atgctattga ctattgtatc atttatgatt ttatttttga
    13681 taacaggacc aatgagctta aaattattga gtaaaaagag cattttagag cttttagtag
    13741 gtacaaaaaa gcctaaaaaa gagataaaat cttcaaagct atttggaata attggtgtaa
    13801 tatgtcttat attaggatat gctatgatac tatttggcaa taagttaaaa ataaatggag
    13861 gtatgtatac aacagcacta ttaattactt tggggatatt tttatttttt tctcaattta
    13921 ctattttgat attaaagtat ttaaaaaata aagaaaaatt ttataagaac aaagtaaata
    13981 tgttacttat aagtaatttg atatataaat taaaggataa tacacgattg ttatttttaa
    14041 taacaatact tttatcggct actttagtag catttacaac aacttcaaca cttgtaagtt
    14101 ctcaaggaga agcttctaaa aataatttcc caatggttta ctcatatttt tcagagcata
    14161 ataatgaaaa agaatatgaa gaactacaac aaattagaga agcaatcaaa ggatatgatt
    14221 ataaggagtt aagttttcct gtacttaaat ataataggga agtcttacta agtgtaaaga
    14281 attataacaa attatcaaag gaattgggat tagataaaat tagttcaaag ttagaaaaat
    14341 atgaagggat tataattcct agtagcaatt cgcaagaaca tataaattct ttaaaacaat
    14401 taaaaaatta tagtataaaa aatttaaata tagaagtaaa aaaatcaaaa aataaaataa
    14461 tttttcctac aggactgttt agtaaagttg tggttataag tgatgactta tacaatgaag
    14521 taaaaggtga attttcaaaa attaattttc atggatttga ttataaaaac tggcaaagca
    14581 gtgcaaagat aactgaaaat ttaaaagaaa aacattttaa tttggataga gaatataaca
    14641 ggtcatattt tttaacatta ccagatatgt atttagtaga gttacaacaa agtaaaattc
    14701 ttcaatttat gggtgttttt ataggagtga tattatttat agcagttttt agttttttat
    14761 acttcagatt atatacagac gagatagaag ataatgtaaa gtacaaaaaa ctatcaaaaa
    14821 taggtctatc ttttaaaaat atgaataaga ttgttagtat agagataggt acattgtttt
    14881 ttataccgta ttttatagca attataaata gcataatttc tttactgttt ttaaatcaag
    14941 tattaaataa tagttttaag ttagaaaatt tgggtatatt actactgata tcatctatat
    15001 attcacttta tttttactta ttaaaaaaaa attatactag aaaagtttgg ttttttgatt
    15061 aaagtggtat ataatagata tataaattaa tatttaaaaa gtagttaata ttaggggagg
    15121 gcatttgcac ctcccttgta atatgtggaa aattgaatat tagaagaagg aggagacttg
    15181 atggaaaatc aacaattatt aggaacagaa cgaattagta aattactact aaaatattct
    15241 ataccagcta taataggtat gttggtaaat agtttatata atgtagtaga tagaattttt
    15301 attggaaata taccaggggt tggaccactt gcaataacag gtcttggtgt aacaatgcca
    15361 ataatgacaa taatacttgc atttgggatg ttgataggta taggaactac tactaccata
    15421 tcaataaaac ttgggcaagg taaagtagaa gaggcaagaa aacttatagg aaatgcaatg
    15481 acgttatctg taataacagg aattatcata atgatacttg gaatattatt tgcaaataaa
    15541 atacttacat tgtttggagc aagtgaaaat actttaatat atgcaaaatc atatatcaat
    15601 attatattat taggtacagt agtaaatctt ctttcctttt ctttaaacca ctcaataaga
    15661 gctgatggta gtcctaaaat ttcagcagga ataatgatag taggatgttt aactaatata
    15721 gttttagact ggatattaat atttggattc aatttgggaa tacaaggagc tgcaattgct
    15781 acagtaactt ctcaggctct tacagctatt ttaactatag ggtattatat aagtggaaaa
    15841 tcaaacttac gattcagtaa atctaatcta aaattagata aaaagctaat aaaagcagtg
    15901 tttgcaatag gtatgtcgcc atttgctatg caacttgcag caagtttagt tcaagtaata
    15961 tcaaatattg cacttaaaac tcatggtgga gatttagcta taggggctat ggctactatt
    16021 tcttctattg caatggtatt tttgatgcct atctttggaa taaatcaagg agcgcaacct
    16081 attataggtt tcaattatgg agctgaaaaa tatgataggg ttaaaaaagc atatttaggt
    16141 tcattagtag tagctactat aattttatgt atgggtatgg tagtagttat gcttttccca
    16201 gaagctatta taggtatatt taataaagac cctgaactta tgaatatatc tgttaatgga
    16261 ttaagaatat acttacttat gttgccaatt gtaggcttat cagttacagg aacaaacttt
    16321 atacaatcta taggaaaagc aaaaatggct atgttattga gccttttaag acaagtaatt
    16381 ttattgatac cagcagtatt aattcttcct acattcttag gtttacaggg tgtatggaca
    16441 gctcaaccag tgtctgattt tatagctaca gtaattacag gtatagttgt atttagagaa
    16501 ttaaaaagat atactcctaa aactgaaaaa ttaaatgaaa atgaaagact aaacgagata
    16561 actactgagt aaaaatataa attcagataa ttgagcaaga aattgcaaaa aatacgatta
    16621 tatgataaaa taaaaccgct gtcaaggata agagaaattc taattatgga gtgattttat
    16681 ggaatttaca aagaaaagca aattaaaaaa tatgtatgta aacatgaatg tagctagaat
    16741 gttgtctaag ataaatgagt ataagggtag acaactgctt tacaaaaaac aaccaaaaga
    16801 aattttagaa aacttagaaa aaaaatcttt agtagattgt tctgaatcta catacattgg
    16861 aaatcaaaga gatagtagta attttaatct agaaaagttg ataagtaatg aagttacacc
    16921 tagaagtaga gaggaattga gtattgttga atacagagat gtggtaaaaa ctattaacag
    16981 tgcttatgag agtattccca tcagttcaca aacaattctt gagcttcatg gatacttata
    17041 taaattttca tctactagag gaggaagtta taagtcagat aatgatttta ttgaacacaa
    17101 tttaaaacct agcgaattta taagtactga ttcaagtgtc aataaagttg aaaaagctgt
    17161 agaagaaata tgtgaagctt ataatacatt gatagaggaa gatgaaattg atatattaat
    17221 attaatttct gcatttgtgt tagatttcat attgatacat ccattcaaag aaggtaatat
    17281 aaaaatggcg agagtactta tcctattgtt actaaataaa aatgggtatg aagttggaag
    17341 atatataagt ttaggaaaga tatttgatga tagttcatat gaatattata gtaatttaaa
    17401 ttatttgaaa gcctcaatag gtagtgaaaa agcagatatg aatgcatgga ttgagtattt
    17461 tttagagacg atattaactg catatgagaa gctggatgat agtttaaata tatctgataa
    17521 gaaaagacaa acaaaaacta gtagaataga gaaaataata aattctaccc ttggatattt
    17581 tacaaaagaa gatataagag atttatgtcc tgacattcca gaacctacta taaatagagt
    17641 ttttaataat ctaagaaaac aagataagat agaagttgtt gcaagaggaa gaagtgcaaa
    17701 atggaagaaa aaatattaaa aaatgtttag ataactaaaa tggtatagtg ttttacacta
    17761 taccattttt aatgtcatta gcatgagcaa taatttaaca acttaagcaa tatcaatttt
    17821 atttattgat tatttttgaa ctgaaaaatg gcgttatatg gtatacctca gtggtaatta
    17881 attttggatg agaagatata atattacaga atatattagg agtatatgta gaaaaaatat
    17941 aataaaagtg tgaggcttag taattaacaa attatgtggc ttcacacttt tttataaaat
    18001 aaagatactt agcagaataa tattttagtt gatatgttta taagatggta cttgtttggg
    18061 taaaagtata aatagtaaaa aagtagaagt aatgtgtata aaaacataag ttacattctg
    18121 taataatagt tattttataa ttcaacaaaa gaatagaatg ggtatatttg tgaaataata
    18181 atataaaata atcttaggag tgagcttatg aagaaaaaat tattatatat aaatgtaaat
    18241 tcaaaacctg aagacttatc ttcaagtaaa actgtagcaa gaaaatttat aaataaattt
    18301 atggaaaaaa ataaagattt tgaggttgaa gagatagacc tttataaaga acatatacca
    18361 agacttgagt atcagtactt tgaaaaaaga aatagcatag ttagtgaaga aaatgctaaa
    18421 aatttagacg ataaggatag aaaagagctt acaaagatta gaaatctttg tgaccaattt
    18481 gtgaatgcaa gtgtttatgt aatagcagca cctatgtgga gtttatcttt tccagcacca
    18541 cttaaagagt atatagattg tataattcaa gatggaaaaa ctatatcttt tgaaggcaat
    18601 gataaaccac aaggaatttt aaatgatatt gatagaagta tggtatatat acaatcttct
    18661 ggtggacaca taccatgggt gttgaagcca gttatgaata aagggttaaa ttatgtggaa
    18721 agtattatga aatttatagg aattaaaaaa tttgatgaat tgttagtaga tggaactgga
    18781 actagtgaag aagaaagaca agctgcaata gaaaaagcat ctgaaaaaat agatggtata
    18841 atagatggga tgaaatttta attataatat tttattaaaa atataaagga aaaacctctt
    18901 ttaatgtaga aacttatatt gaaggaggcg agaatcatgc gagaagaaaa aagtaatgaa
    18961 aagtatgatt gttattggtg taatcaagag aataatttct gtgtagaaat aaaagataat
    19021 atagtcatga tagatgatgg cactggtacg ttaaaacaag ccgttttcat agggtataaa
    19081 caaatccaaa ttaatttaaa ctgttcacat tgtcaaaact taaatagaat aaaattaaat
    19141 ttgtagaatt ttaaaatgga aattattgaa ggaattaaaa atagaaagtg ttaatattta
    19201 gactgaaaat tatattttat acaataaaag tttatttaaa taacattgta ttttaatatt
    19261 tattttcagt cttactttat taaaattatt ttttggttat gtctggaaaa tatctgtcta
    19321 ctaatttttc tgaaatattt tttaattggt cagccattga agtcagactt aataaggcta
    19381 tcaataaatc atctttattt tctggattta tactaatatt ttcaaaatta gactctataa
    19441 agtccggtat attctttctt tgattttctt ttattaacat gaatttttcg taacatgaaa
    19501 ctaaatcttt ttcactgaaa ttatcctttt catacacacc atgtaagatt cttttaattt
    19561 cttgtattgt aagtgtattt ttcatagaat aaataattat catctgtaaa atttgttctt
    19621 tagtatactt ttttccctta actggtttga ttaatccctc tttgctgtaa ttatttatca
    19681 tggttttagt aagaatttta tcactttcaa atcttttatt agcagaaagc ttattgtcaa
    19741 ttagagaaat aatttgatcc atatataagt caatagatgg aatatcgttt gaagttatat
    19801 ctgcattatt tagtgtttct agtattatag tattaagttc attattcatc atatgttacc
    19861 tccataatat atataataca ctaaattaga aagtaaaaca atattaaggc ttgtaaaaaa
    19921 aacataaagt ggtataatta aatatataat atagtaatca aaactatatt tatgaatctg
    19981 atttttaaaa tacataattg taggaggacg aaatgtatca atttttttta aagggtagag
    20041 acccaataag cagtttaact cattttatag gtgcttgttt atctctttta gcaactataa
    20101 ttttagtttt tcaatctgtt acattacagg aaacttctct cttgatgata gtatctgtat
    20161 ctgtatttgg actttcacta attgctttat atagtgcaag ttcgtattat cattttttaa
    20221 aggggacacc agaacaagaa ttgtttttta gaaaagtaga ccatgcaatg atttacgtat
    20281 tgattgctgg ctcttataca ccaatatgtc tgaattttat ggaaaaaaaa gaaggcataa
    20341 tatttgttac agcaatatgg atagttgcat ttattggcat aataataaaa atattttgga
    20401 tggatgcacc tagatggtta tctaccagta tatatttact tatggggtgg gcaattgttt
    20461 ttgatataaa tgcattcaat tcaattccta aggattgcct tagactatta attatggaag
    20521 gtgtatctta ctctataggt gcgattattt atataattaa aaagcctaat ataagtcctg
    20581 agtttggatt tcatgaaata tttcatattt ttattatgat aggttcttta tttcactttt
    20641 tagcagtttt attgtatgtt ttatagtttt aaaagatttg attaattgat actaaaattc
    20701 tacaatgaat aaaatggaac tgccttatat agattatatc ttagacaata agacagttcc
    20761 ttattataaa tattaaattc tacttataat aaaattttga taaaaatagt ccattcaaaa
    20821 tgcctattcc ataattcctt taatgtactt ttcatttacg acatatagtt tgaatttatg
    20881 tactataatt atatcctcta aattctctga aacactaaca attctgacac atttgtttct
    20941 aatttctaca ggtaaatcta aatcatttgt taaattcaca tagtcatcat atttatacat
    21001 aaaatcatcc ctttacatta agatatactt attatactat attttaataa gtttttttaa
    21061 attattacaa tttttcccga aatttcattt tttatacata aaatttccaa attaggtaaa
    21121 gattaaattt tttattgtat aaacaaaagt tacatataaa atattttatt caatttttta
    21181 aataactatt gccaattttt gaaaaatata ttattattaa tagtaacaaa aaactgtaaa
    21241 tttagaatat taataaaaat tatttgggag gaaattatca tggtgagatt aaatatagta
    21301 aaattaaata caaaattaaa tcatcaccat catcatagat taaagggatt gtaatatgaa
    21361 attaattcat agacacaagc cctgttttta gtgtaattgg tcttgtatct atgatgggaa
    21421 gtaattttaa gagaaaatta tagccatata ggtataaagc ctatgtggct tttttattgt
    21481 tttaaatttg caaatataag agtaaattta atgaagaggg tgagaatgtg aaatttttga
    21541 ggattgaaga tgaggttatt tattctaaaa aaagatataa attaaaaagg gaaatagata
    21601 aacttttttt ggatgaagaa tattttcaaa tagaaccaca attatttgaa gaatatgatg
    21661 aatttacaac tataaataat aaaattccag aagaatctat ggtaaaggtt gtaaatggaa
    21721 aagtaatggt acttagagct gatataacta caagtataat aaaaagcctt gtaccaagat
    21781 gggaagatgg tttaaagctt aagctttttt ataattcatc aatatataaa aataaaaata
    21841 cagttggaat aaaagagata agacaaatag gttgtgagta tctaggagaa gcctctgtag
    21901 aagcagatag agaagtagtg aaattagctc ttaagatact tgaaaaatac aataataatt
    21961 ttattctaga ggttgggagt agcaagtata ttcatggttt gttagaagaa ttaaatttaa
    22021 ataagaattg tgaaaatcaa attaaaaatt tactatatac gaagaacact catgaactaa
    22081 aagtatatat tgaagaatta aaaattaagc gtgaagtaaa agagttatta tcaaatattt
    22141 taagtttaca agggaattta tataatgtta ttgaaaaatc aaacaagttc tattgtaata
    22201 ataagatgaa gcaagctctt gaagaattaa agcaagtaaa taacttgatt gaggaatgta
    22261 attttttaga taaggctaga tttgatttat caatgattac tatgcttgac tattatgaag
    22321 gaattatgtt tagaggatac tacccaaact catataaaga aattcttagt ggtggaagat
    22381 atgattcttt aactaaagag tatggaaaag aaattccagc cattggattt acactaagtg
    22441 ttgatgagtt aatgaagtat gtatataagt aaagtttaga aggagggatt gctttggatt
    22501 atttgactat agcactagca aaaggacgaa ttgaagggga atcatttaaa aaatttaaaa
    22561 aaatgggtct aggagacagt atagacacag atacgagaaa actaattttt aaagatgaag
    22621 aaaataaaat tatatatata catgtaaagc catcagatgt agttacatat gttgaaaaag
    22681 gagtcgctga cctcggtata gcaggtaaag atactatttt agagaatgag acagatgtat
    22741 atgaaatata tgatttaggt tttggaaaat gtaaatttgc tgtagcagga ttaaagggag
    22801 atagcatata tagagaagat gaatatttaa aagtggcaac aaagtatccc aatatagcaa
    22861 aaaagtattt taaagagaaa ggtcaaaaaa ttgaaataat aaaattaaat ggttctgtag
    22921 aactagctcc aatagtaggg ttgtcagatg taattgtaga tatagttgag actggcaata
    22981 cacttaaagc aaatggtctt gaaatattag aagacatatg taatataagt gctagaatta
    23041 tatcaaatag agctagctat agatttaaat atgaacaaat tcagaatata attcgtttat
    23101 ttgaagaact tgataattaa aatataattg agctttataa ggagggattt aagttgagag
    23161 aaaaagaaag cataagagag ttaaagggat atgaaccaaa tcacgtaaac tgtaaagtaa
    23221 aacttgatgc aaatgaagga agtaagaggt tgtttaaata ccttattaaa gaaatttcag
    23281 atagtgatat agatttaaat ttatatcctg aagattctta tagtgatttg aaagaatcta
    23341 taatagatta cataaatatt tctggagtaa ataagaaaaa tcttctagta ggaaacggtt
    23401 caagtgaaat aattgattta ataatacata cttttgtaga taaagatgaa gtaatattga
    23461 gtttctctcc aagttttagt atgtattcta tatatagtca gataaatggg tctaaattta
    23521 taggtgttga aagtgatgaa aatttagtta taaatataga taatgtgatt gaaaaagtaa
    23581 aggagaataa tcctaaaata gtaattgtat gtaatcctaa taatccaact ggaacaatat
    23641 taaagaggga agagataata aagcttttag attcaactaa tagtctagtg gttttagatg
    23701 aagcatatat ggattttgga gaagaaagca tgttaagtga tgtttttaag tatgataatc
    23761 taatagttct tagaacttta tcaaaggcat ttggattggc tggaataaga acaggatata
    23821 tgttatctaa tagtagttta ataaattctg ttgagaaagt aagacctcca tataatttaa
    23881 attcattatc agactttatt gctacaagag cacttagaaa taaagatgtg gtaaaggctt
    23941 atataaagga agtaaaagag gaaagagaag ttttatataa agaaatgatt ggtatgggaa
    24001 ttaaagcata taaatcacaa gcaaatttta tattatttta ttctgaaatc gaaaatttat
    24061 cacaaaaact tattgataga ggtgttttaa taagaaaatt tggtggaaag ttagaaaatt
    24121 attacagagt tacaattggt gataaagaag aaaattctat gtttgttgga gctataagag
    24181 atattttgaa aaaggagaaa taggtatgag aatttggaag gtagaaagaa atactcttga
    24241 aacacagatt ttagtagaat taaatattga tggttctggt aaagctgaaa tagatactgg
    24301 aataggattt ttagaccata tgcttacctt aatgtcattt catggcaagt tcgatttaaa
    24361 agtgatttgt aagggtgata catatgtaga tgaccaccat agtgtagaag atataggtat
    24421 agctataggt gaagcattta aaaatgctct aggtgacaaa aaaggaatac gaagatattc
    24481 taatatctat atacctatgg atgaatctct atcaatggta gcaatagata taagcaatag
    24541 accttatctt gtatttaatg ctaaatttga tacccaaatg attggtagta tgagtactca
    24601 atgctttaaa gaatttttta gagcttttgt aaatgaatcg agagtaacat tacatatcaa
    24661 tctcttatat ggggaaaatg accatcataa gatagaaagt atttttaaag catttgcaag
    24721 agctttaaaa gagggtagtg aaatagtttc taatgagata gcatcttcaa agggggtttt
    24781 gtagaatgaa tataatagta gactatggtc ttggaaatat agattctgtg tctaggggtt
    24841 ttagaaaagc tggaatagaa actaaaattt ctagtgatat agatgaaata aaacaggcag
    24901 attcacttat acttccaggt gttggagctt ttagagattc tataagtgcc ttagataaac
    24961 taggattgat accaataata aaggagcatg tttctaaggg taaatttatg ataggtatat
    25021 gtctaggaat gcaattactt tatgaaaaaa gttatgagta tggagaatat gaaggattag
    25081 gacttataaa aggaagtatt gataaactgg atataagttt aaaagtgcca catatgggat
    25141 ggaataatct aaaatttaat aaggcaaatg atgatatact taaatatata aatgaagatg
    25201 attatgtata cttcgttcac tcatattatg caaattcatc aaatgaagaa ctaattgcat
    25261 tttcagaata tgaaaagaaa atccctgcta ttgttagaaa aggcaatgta tatggtatac
    25321 aatttcatcc tgaaaaaagt ggagaagtag ggttaaatat attaagagca tatggggaga
    25381 tgataaaatg ataatatttc cagcaataga tataaaagat aataagtgtg taagacttac
    25441 acaaggagaa tttgacaaag taaatgtata ttatgataat ccattagaag tagcatataa
    25501 atggaaaaat gaaggagcag aatatataca tatagtagat ttaaatggtg ctagaagtga
    25561 atttggtgta aatacaaaaa taattgagga catagcaaac aatatagata tacctattca
    25621 agttggcggt ggagttaggg ataaggaaaa agtcaaaagt ttaataaatg ctggtgttac
    25681 tagagtaata ttaggtagta tagcgattga aaatttgaat ttagttgaag aattggtcaa
    25741 tgaatataaa gagaaaattg tagtttctat agatgctaaa gatggaaaag tagcagttag
    25801 gggatgggaa gttgtaagca atgtagactc attaacatta tgcaaacaac ttgaaaagat
    25861 aggtgtacaa actattgttt atacagatat atcaaaagat gggatgttgc aaggtccaaa
    25921 ttttgacata tatgaaagaa tagcaaagga aacatcacta aatgttattg cttctggagg
    25981 cgtaacttct atagaagacg taaaaagact aaaagctatg aacttatatg gtgcaataat
    26041 aggtaaagcg ctttatgata aaaagataga ctttaaggag gcacaacaat tatgcttact
    26101 aggagaataa taccttgtct agatgtgaga aatggaagag tcgtaaaggg aaaaaaattt
    26161 aaagatatag tagatgttga tagtccagaa gtacttggaa aattttatag tgattgtggt
    26221 gcagatgaac ttgtattcta tgatataact gcatcaaatg aagagagaaa gacatcttta
    26281 gaatttgtga caaaagttgc agaaaatata aatataccat tttgtgttgg tggaggagta
    26341 aataaattag aagatttcac tgatatttta agaaaaggtg ctgataaagt ttctataaat
    26401 tcatcagcag tcaaaaatcc tgaattaata agggaagctt cattaaaatt tggagcacaa
    26461 tgtgttgttt tatcgataga tgcaaagaaa aatgaagagg gttcatggag cgtatacgta
    26521 aaaggtggaa gagaaaaaac taatctggat gcaattgaat gggctgttaa aggtgtagaa
    26581 cttggagcag gagaaatcgt tgtaaatagt atggatgaag atggaatgaa aaatggatat
    26641 gatatagaat tattatcaaa gataacttct ttagtaaatg tacctgtcat agcatctgga
    26701 ggcgctggaa aaaaggaaga tttttatgag gcggttaata aatccaatgt agatggaatt
    26761 ttagcagcat ctgtttttca ttttggcgag ataaaaataa acgatttaaa gaaatattta
    26821 aaagacatgg gtgtagaagt aagattataa gttaaatact aaaaggagat tagaaatatg
    26881 gataataagt gtaacaatgt atacagtgat gaagtagaga aatttataag aagtataaag
    26941 tttgatgata aagggttagt ccctgttgtt gttcaagagg tagttagcaa agatgtactg
    27001 atgttagcat atatgaataa agatgctata aagaaaacct taaaagataa agtagcttgc
    27061 tattttagta gaagtagaca agaactttgg gttaaaggtg agacatctgg taatactcaa
    27121 aaagtagtta agatgtctta tgattgtgat gtagatacta tactactttt tgttgaacaa
    27181 actggtgtag cttgtcatac aggcaattat tcttgttttt acagagactt gtttgatgat
    27241 agttcaaaaa tggagcttga agtacaaaca aatatattga aagaattata tgatttaatc
    27301 aatgaaagaa aaaataatcc agttgaaggt tcttatacta attatctttt tgaaaaagga
    27361 atagataaga ttcttaaaaa agtaggtgaa gagagtagtg aggtaattat agcatcaaaa
    27421 aataccgata aaagtgaact tatttacgaa attagcgatt tagtatatca tacattggtt
    27481 ttaatgatag aaaaaggtgt tgaaattgat gaaataaaaa aagaattact taaaaga
//
LOCUS       DAEPHU010000060        27436 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 01A10CD0081
            SAMN05941466-rid12468953.denovo.060, whole genome shotgun sequence.
ACCESSION   DAEPHU010000060 DAEPHU010000000
VERSION     DAEPHU010000060.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941466
            Sequence Read Archive: SRR6291087
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 27436)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 27436)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068158.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 22:43:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,892
            CDSs (total)                      :: 3,805
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 87
            rRNAs                             :: 8, 1, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 55
            CDSs (without protein)            :: 55
            Pseudo Genes (ambiguous residues) :: 0 of 55
            Pseudo Genes (frameshifted)       :: 21 of 55
            Pseudo Genes (incomplete)         :: 28 of 55
            Pseudo Genes (internal stop)      :: 16 of 55
            Pseudo Genes (multiple problems)  :: 8 of 55
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..27436
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941466-rid12468953.denovo.060"
                     /strain="01A10CD0081"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            <1..361
                     /gene="tcdR"
                     /locus_tag="KR231_002623"
     CDS             <1..361
                     /gene="tcdR"
                     /locus_tag="KR231_002623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="glycosylating toxin sigma factor TcdR"
                     /protein_id="HBH0004987.1"
                     /translation="KSDAIIVKYIHKSLLNKTFELSRRYSKMKFNFVEFDENILNMKN
                     NYQSKSIFEEDICFFGYILKELSGIQRKVIFYKYLKGYSDREISVKLKISRQAVNKAK
                     NRAFKKIKKDYENYFNL"
     gene            679..7779
                     /gene="tcdB"
                     /locus_tag="KR231_002624"
                     /gene_synonym="toxB"
     CDS             679..7779
                     /gene="tcdB"
                     /locus_tag="KR231_002624"
                     /gene_synonym="toxB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_074049122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosylating toxin TcdB"
                     /protein_id="HBH0004988.1"
                     /translation="MSLVNRKQLEKMANVRFRTQEDEYVAILDALEEYHNMSENTVVE
                     KYLKLKDINSLTDIYIDTYKKSGRNKALKKFKEYLVTEVLELKNNNLTPVEKNLHFVW
                     IGGQINDTAINYINQWKDVNSDYNVNVFYDSNAFLINTLKKTVVESAINDTLESFREN
                     LNDPRFDYNKFFRKRMEIIYDKQKNFINYYKAQREENPELIIDDIVKTYLSNEYSKEI
                     DELNTYIEESLNKITQNSGNDVRNFEEFKNGESFNLYEQELVERWNLAAASDILRISA
                     LKEIGGMYLDVDMLPGIQPDLFESIEKPSSVTVDFWEMTKLEAIMKYKEYIPEYTSEH
                     FDMLDEEVQSSFESVLASKSDKSEIFSSLGDMEASPLEVKIAFNSKGIINQGLISVKD
                     SYCSNLIVKQIENRYKILNNSLNPAISEDNDFNTTTNTFIDSIMAEANADNGRFMMEL
                     GKYLRVGFFPDVKTTINLSGPEAYAAAYQDLLMFKEGSMNIHLIEADLRNFEISKTNI
                     SQSTEQEMASLWSFDDARAKAQFEEYKRNYFEGSLGEDDNLDFSQNIVVDKEYLLEKI
                     SSLARSSERGYIHYIVQLQGDKISYEAACNLFAKTPYDSVLFQKNIEDSEIAYYYNPG
                     DGEIQEIDKYKIPSIISDRPKIKLTFIGHGKDEFNTDIFAGFDVDSLSTEIEAAIDLA
                     KEDISPKSIEINLLGCNMFSYSINVEETYPGKLLLKVKDKISELMPSISQDSIIVSAN
                     QYEVRINSEGRRELLDHSGEWINKEESIIKDISSKEYISFNPKENKITVKSKNLPELS
                     TLLQEIRNNSNSSDIELEEKVMLTECEINVISNIDTQIVEERIEEAKNLTSDSINYIK
                     DEFKLIESISDALCDLKQQNELEDSHFISFEDISETDEGFSIRFINKETGESIFVETE
                     KTIFSEYANHITEEISKIKGTIFDTVNGKLVKKVNLDTTHEVNTLNAAFFIQSLIEYN
                     SSKESLSNLSVAMKVQVYAQLFSTGLNTITDAAKVVELVSTALDETIDLLPTLSEGLP
                     IIATIIDGVSLGAAIKELSETSDPLLRQEIEAKIGIMAVNLTTATTAIITSSLGVASG
                     FSILLVPLAGISAGIPSLVNNELVLRDKATKVVDYFKHVSLVETEGVFTLLDDKIMMP
                     QDDLVISEIDFNNNSIVLGKCEIWRMEGGSGHTVTDDIDHFFSAPSITYREPHLSIYD
                     VLEVQKEELDLSKDLMVLPNAPNRVFAWETGWTPGLRSLENDGTKLLDRIRDNYEGEF
                     YWRYFAFIADALITTLKPRYEDTNIRINLDSNTRSFIVPIITTEYIREKLSYSFYGSG
                     GTYALSLSQYNMGINIELSESDVWIIDVDNVVRDVTIESDKIKKGDLIEGILSTLSIE
                     ENKIILNSHEINFSGEVNGSNGFVSLTFSILEGINAIIEVDLLSKSYKLLISGELKIL
                     MLNSNHIQQKIDYIGFNSELQKNIPYSFVDSEGKENGFINGSTKEGLFVSELPDVVLI
                     SKVYMDDSKPSFGYYSNNLKDVKVITKDNVNILTGYYLKDDIKISLSLTLQDEKTIKL
                     NSVHLDESGVAEILKFMNRKGNTNTSDSLMSFLESMNIKSIFVNFLQSNIKFILDANF
                     IISGTTSIGQFEFICDENDNIQPYFIKFNTLETNYTLYVGNRQNMIVEPNYDLDDSGD
                     ISSTVINFSQKYLYGIDSCVNKVVISPNIYTDEINITPVYETNNTYPEVIVLDANYIN
                     EKINVNINDLSIRYVWSNDGNDFILMSTSEENKVSQVKIRFVNVFKDKTLANKLSFNF
                     SDKQDVPVSEIILSFTPSYYEDGLIGYDLGLVSLYNEKFYINNFGMMVSGLIYINDSL
                     YYFKPPVNNLITGFVTVGDDKYYFNPINGGAASIGETIIDDKNYYFNQSGVLQTGVFS
                     TEDGFKYFAPANTLDENLEGEAIDFTGKLIIDENIYYFDDNYRGAVEWKELDGEMHYF
                     SPETGKAFKGLNQIGDYKYYFNSDGVMQKGFVSINDNKHYFDDSGVMKVGYTEIDGKH
                     FYFAENGEMQIGVFNTEDGFKYFAHHNEDLGNEEGEEISYSGILNFNNKIYYFDDSFT
                     AVVGWKDLEDGSKYYFDEDTAEAYIGLSLINDGQYYFNDDGIMQVGFVTINDKVFYFS
                     DSGIIESGVQNIDDNYFYIDDNGIVQIGVFDTSDGYKYFAPANTVNDNIYGQAVEYSG
                     LVRVGEDVYYFGETYTIETGWIYDMENESDKYYFNPETKKACKGINLIDDIKYYFDEK
                     GIMRTGLISFENNNYYFNENGEMQFGYINIEDKMFYFGEDGVMQIGVFNTPDGFKYFA
                     HQNTLDENFEGESINYTGWLDLDEKRYYFTDEYIAATGSVIIDGEEYYFDPDTAQLVI
                     SE"
     gene            7901..8401
                     /gene="tcdE"
                     /locus_tag="KR231_002625"
     CDS             7901..8401
                     /gene="tcdE"
                     /locus_tag="KR231_002625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="holin-like glycosylating toxin export protein
                     TcdE"
                     /protein_id="HBH0004989.1"
                     /translation="MHSSSPFYISNGNKIFFYINLGGVMNMTISFLSEHIFIKLVILT
                     ISFDTLLGCLSAIKSRKFNSSFGIDGGIRKVAMIACIFFLSVVDILTKFNFLFMLPQD
                     CINFLRLKHLGISEFFSILFILYESVSILKNMCLCGLPVPKRLKEKIAILLDAMTDEM
                     NAKDEK"
     gene            8480..8641
                     /locus_tag="KR231_002626"
     CDS             8480..8641
                     /locus_tag="KR231_002626"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0004990.1"
                     /translation="MKLIMKTREQMPRDTQVLNTYNFEASVHYYIDDKVVYQTLVHKD
                     GAWSVGKIY"
     gene            8730..8912
                     /locus_tag="KR231_002627"
     CDS             8730..8912
                     /locus_tag="KR231_002627"
                     /inference="COORDINATES: protein motif:HMM:NF022413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0004991.1"
                     /translation="MRDEGQNDIENKYQTLINDLIDSLKVIGKIYKEIKTLKKYKICL
                     QITIRQSPYLIEESIN"
     gene            9129..17198
                     /gene="tcdA"
                     /locus_tag="KR231_002628"
                     /gene_synonym="toxA"
     CDS             9129..17198
                     /gene="tcdA"
                     /locus_tag="KR231_002628"
                     /gene_synonym="toxA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_105161403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosylating toxin TcdA"
                     /protein_id="HBH0004992.1"
                     /translation="MSLISKEELIKLAYSIRPRENEYKTILTNLDEYNKLTTNNNENK
                     YLQLKKLNESIDVFMNKYKTSSRNRALSNLKKDILKEVILIKNSNTSPVEKNLHFVWI
                     GGEVSDIALEYIKQWADINAEYNIKLWYDSEAFLVNTLKKAIVESSTTEALQLLEEEI
                     QNPQFDNMKFYKKRMEFIYDRQKRFINYYKSQINKPTVPTIDDIIKSHLVSEYNRDET
                     VLESYRTNSLRKINSNHGIDIRANSLFTEQELLNIYSQELLNRGNLAAASDIVRLLAL
                     KNFGGVYLDVDMLPGIHSDLFKTISRPSSIGLDRWEMIKLEAIMKYKKYINNYTSENF
                     DKLDQQLKDNFKLIIESKSEKSEIFSKLENLNVSDLEIKIAFALGSVINQALISKQGS
                     YLTNLVIEQVKNRYQFLNQHLNPAIESDNNFTDTTKIFHDSLFNSATAENSMFLTKIA
                     PYLQVGFMPEARSTISLSGPGAYASAYYDFINLQENTIEKTLKASDLIEFKFPENNLS
                     QLTEQEINSLWSFDQASAKYQFEKYVRDYTGGSLSEDNGVDFNKNTALDKNYLLNNKI
                     PSNNVEEAGSKNYVHYIIQLQGDDISYEATCNLFSKNPKNSIIIQRNMNESAKSYFLS
                     DDGESILELNKYRIPERLKNKEKVKVTFIGHGKDEFNTSEFARLSVDSLSNEISSFLD
                     TIKLDISPKNVEVNLLGCNMFSYDFNVEETYPGKLLLSIMDKITSTLPDVNKNSITIG
                     ANQYEVRINSEGRKELLAHSGKWINKEEAIMSDLSSKEYIFFDSIDNKLKAKSKNIPG
                     LASISEDIKTLLLDASVSPDTKFILNNLKLNIESSIGDYIYYEKLEPVKNIIHNSIDD
                     LIDEFNLLENVSDELYELKKLNNLDEKYLISFEDISKNNSTYSVRFINKSNGESVYVE
                     TEKEIFSKYSEHITKEISTIKNSIITDVNGNLLDNIQLDHTSQVNTLNAAFFIQSLID
                     YSSNKDVLNDLSTSVKVQLYAQLFSTGLNTIYDSIQLVNLISNAVNDTINVLPTITEG
                     IPIVSTILDGINLGAAIKELLDEHDPLLKKELEAKVGVLAINMSLSIAATVASIVGIG
                     AEVTIFLLPIAGISAGIPSLVNNELILHDKATSVVNYFNHLSESKKYGPLKTEDDKIL
                     VPIDDLVISEIDFNNNSIKLGTCNILAMEGGSGHTVTGNIDHFFSSPSISSHIPSLSI
                     YSAIGIETENLDFSKKIMMLPNAPSRVFWWETGAVPGLRSLENDGTRLLDSIRDLYPG
                     KFYWRFYAFFDYAITTLKPVYEDTNIKIKLDKDTRNFIMPTITTNEIRNKLSYSFDGA
                     GGTYSLLLSSYPISTNINLSKDDLWIFNIDNEVREISIENGTIKKGKLIKDVLSKIDI
                     NKNKLIIGNQTIDFSGDIDNKDRYIFLTCELDDKISLIIEINLVAKSYSLLLSGDKNY
                     LISNLSNTIEKINTLGLDSKNIAYNYTDESNNKYFGAISKTSQKSIIHYKKDSKNILE
                     FYNDSTLEFNSKDFIAEDINVFMKDDINTITGKYYVDNNTDKSIDFSISLVSKNQVKV
                     NGLYLNESVYSSYLDFVKNSDGHHNTSNFMNLFLDNISFWKLFGFENINFVIDKYFTL
                     VGKTNLGYVEFICDNNKNIDIYFGEWKTSSSKSTIFSGNGRNVVVEPIYNPDTGEDIS
                     TSLDFSYEPLYGIDRYINKVLIAPDLYTSLININTNYYSNEYYPEIIVLNPNTFHKKV
                     NINLDSSSFEYKWSTEGSDFILVRYLEESNKKILQKIRIKGILSNTQSFNKMSIDFKD
                     IKKLSLGYIMSNFKSFNSENELDRDHLGFKIIDNKTYYYDEDSKLVKGLININNSLFY
                     FDPIEFNLVTGWQTINGKKYYFDINTGAALTSYKIINGKHFYFNNDGVMQLGVFKGPD
                     GFEYFAPANTQNNNIEGQAIVYQSKFLTLNGKKYYFDNDSKAVTGWRIINNEKYYFNP
                     NNAIAAVGLQVIDNNKYYFNPDTAIISKGWQTVNGSRYYFDTDTAIAFNGYKTIDGKH
                     FYFDSDCVVKIGVFSTSNGFEYFAPANTYNNNIEGQAIVYQSKFLTLNGKKYYFDNNS
                     KAVTGWQTIDSKKYYFNTNTAEAATGWQTIDGKKYYFNTNTAEAATGWQTIDGKKYYF
                     NTNTAIASTGYTIINGKHFYFNTDGIMQIGVFKGPNGFEYFAPANTDANNIEGQAILY
                     QNEFLTLNGKKYYFGSDSKAVTGWRIINNKKYYFNPNNAIAAIHLCTINNDKYYFSYD
                     GILQNGYITIERNNFYFDANNESKMVTGVFKGPNGFEYFAPANTHNNNIEGQAIVYQN
                     KFLTLNGKKYYFDNDSKAVTGWQTIDGKKYYFNLNTAEAATGWQTIDGKKYYFNTNTF
                     IASTGYTSINGKHFYFNTDGIMQIGVFKGPNGFEYFAPANTHNNNIEGQAILYQNKFL
                     TLNGKKYYFGSDSKAVTGLRTIDGKKYYFNTNTAVAVTGWQTINGKKYYFNTNTSIAS
                     TGYTIISGKHFYFNTDGIMQIGVFKGPDGFEYFAPANTDANNIEGQAIRYQNRFLYLH
                     DNIYYFGNNSKAATGWVTIDGNRYYFEPNTAMGANGYKTIDNKNFYFRNGLPQIGVFK
                     GSNGFEYFAPANTDANNIEGQAIRYQNRFLHLLGKIYYFGNNSKAVTGWQTINGKVYY
                     FMPDTAMAAAGGLFEIDGVIYFFGVDGVKAPGIYG"
     gene            complement(17533..18111)
                     /locus_tag="KR231_002629"
     CDS             complement(17533..18111)
                     /locus_tag="KR231_002629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888448.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toxin regulator"
                     /protein_id="HBH0004993.1"
                     /translation="MFFGNISSPACSEDHEEVISNQTSVIDSQKTEIETLNSKLSDAE
                     PWFKMKDDEKKAIEAENQRKAEEAKKAEEAKKAEEQRKKEEEEKKGYDTGITYDQLAR
                     TPDDYKYKKVKFEGKVIQVIEDGDEVQIRLAVSGNYDKVVLCSYKKSITPSRVLEDDY
                     ITIRGISAGTITYESTMGGNITIPGIAVEKIN"
     gene            18658..18903
                     /locus_tag="KR231_002630"
     CDS             18658..18903
                     /locus_tag="KR231_002630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Pathogenicity locus"
                     /protein_id="HBH0004994.1"
                     /translation="MGELQKIPGVGKATEKSLIMLGYTTIKSLKDANPAQMYEKECLI
                     RGQHIDRCQLYVYRCAVYFASTENPEPEKLKWWYWKD"
     gene            complement(19121..19390)
                     /locus_tag="KR231_002631"
     CDS             complement(19121..19390)
                     /locus_tag="KR231_002631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3795 domain-containing protein"
                     /protein_id="HBH0004995.1"
                     /translation="MFESRCGVCCDSCTKKEQVNCTGCPTMEKPFWGGECKVKTCCES
                     KELNHCGECDTFPCDMLLNKGKDQGFDPMVNIEQCRKWLEETVSN"
     gene            complement(20268..21005)
                     /locus_tag="KR231_002632"
     CDS             complement(20268..21005)
                     /locus_tag="KR231_002632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBH0004996.1"
                     /translation="MLRKSVLGEILKLKNSFIWYVLLALPLISVLIGSGNFYLNQGIL
                     KKEWYSLWTQVSLFYGEFFFPILIAIFCAYICRLEHMNHNWNNVMTLPVNLKNIFLSK
                     LTVVSILTAITQVFFVIFYIVAGNMFGFSGSVPKELTGWIAKGWIISISIASIQLYMS
                     IKIRSFATPIGISLCLSLFGMGLIVAKPAVGIFFPYSMLGSAMGVIKQSALNVNDTIV
                     TICVAFITTIVFSEIANRNFRKNDVIS"
     gene            complement(21017..21778)
                     /locus_tag="KR231_002633"
     CDS             complement(21017..21778)
                     /locus_tag="KR231_002633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBH0004997.1"
                     /translation="MKYLGLEFYKLKRKKIILMTFLFVAVEIMWCIINSNRAITRNPD
                     MLGGFEYSYMFMSFASLNGLFFPILISIITSRISDIEHKGDTWKLLKSSVTSLNSIYL
                     SKFLCSAILVSIPVLMQVLSIVLFGHFRGVIESISVSLLLKYTLGTILVSIAIIALHL
                     WIATVIPNQMIAITFGMIGSFIGLTSGLFYQGIRRLFIWSYYLELSPLSYAYDNVLGS
                     SVYRIDMNFSITILVFLIGMLIYYIGRNHLLKKEV"
     gene            complement(21778..22692)
                     /locus_tag="KR231_002634"
     CDS             complement(21778..22692)
                     /locus_tag="KR231_002634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH0004998.1"
                     /translation="MEMIIRTQRLSKEYNKIFRVKDIDLRVPQGAVYGFLGPNGAGKS
                     TTLKMLLGLAKPTQGNINILGKELNEKNRISILKDIGSLIESPSYYGHLTGLENMTIM
                     QKLLDLPKKNVNEALKIVRLENQKNKKVSQYSLGMKQRLGIAMAIMKFPKLLILDEPT
                     NGLDPAGIEEIRELIKSLPEKYGMTVLISSHLLSEIDQIATSIGIINHGELVFQDSIK
                     ELHNRGQSQIAIKTKNVVSAQKLLNTKGYMSLIQDGYLTIENLKDSDVAKINGMLVHS
                     NIDVFRIEEHKKSLEDIFLELTGKAVTL"
     gene            22863..23570
                     /locus_tag="KR231_002635"
     CDS             22863..23570
                     /locus_tag="KR231_002635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBH0004999.1"
                     /translation="MESIKDKKILVVDDHKELLKMIDEILRKEGFSRVFLASSYEEAV
                     RVFRNVKPDCAILDVVLPDGDGFSIMRKIRETSKIPVIFLSARGEDEDRLIGLGLGAD
                     DYIVKPFLPKELTLRLVGILNRVYVPIEEEELPVFKLGDSVVVNLNSACVEKDGQEIS
                     LTAKEHSLLLKLYENKGRIVTNDSLCQAIWGDDMYGYENTLMVHVRRVREKIEKTPST
                     PKHLITVRGLGYKLMIN"
     gene            23615..25021
                     /locus_tag="KR231_002636"
     CDS             23615..25021
                     /locus_tag="KR231_002636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBH0005000.1"
                     /translation="MDSVKYILRRFIGSSILISLLFIVLNIAGFLLFSYMLFVSKYSD
                     NLDTSDSREIKSNLIMIEDNLILRNGKFILDDSSKEVLHKNKVWAMLIDNNGDRIWGF
                     DLPKEIPSHYTLTDVAKFSRFFLKDYPVYVWEHPNGILVTGYPKDKYTKFNLTYTVKE
                     IEQFPMLIIGMFLVNAIVTFLIALFIGLKMVKSIKPIITGIKLMSKGEPVLLQEKGIL
                     SDISKSINTVSKELQMKDEKLRKKEEARSNWIAGISHDIRTPLSMIIGYAGELEESSS
                     LSNREQEQVSIICNQGIKIRELVNDLNLVSKLEYNMQALNCDKIRVSAFLRELISEFI
                     NNNLDNDFYVEFDILNEDIIIDADKKLLKRAISNLIQNSITHNQQGCNIRVTSKSDLD
                     FCYIIVEDDGKGMSQERINSLLKSQNGLSEAYAKGQNHGLGILIVSGIINAHRGKLDI
                     TSIDSQGLKTILKLPLIK"
     gene            26820..27209
                     /locus_tag="KR231_002637"
     CDS             26820..27209
                     /locus_tag="KR231_002637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
                     /protein_id="HBH0005001.1"
                     /translation="MTIKKLPQSELKIMKFIWKSDSKVTSRDIVLGMEQKYQWKQTTT
                     LTLLSRLVVKRFLNSQKIDKYTHYEVLIKEKEYIGVETRDFFRNIHDSSIKSLLLSLH
                     ENINLSKDDILLIEEWIKNLKEEEKDV"
BASE COUNT        10805 a         3070 c         4218 g         9343 t
ORIGIN      
        1 aaaaagcgat gctattatag tcaaatatat tcataaatca ttactgaata agacttttga
       61 gttgtctaga agatattcta aaatgaagtt taattttgta gaatttgatg aaaatatctt
      121 aaatatgaaa aataattatc aaagtaagtc tatttttgag gaagatattt gttttttcgg
      181 atatattttg aaagaattat ctggtattca aagaaaagtt attttttata aatatttaaa
      241 aggatattct gatagagaaa tatcagtgaa attaaaaata tctagacaag ctgttaataa
      301 ggctaaaaat agagcattta aaaaaataaa aaaagactat gaaaattatt ttaacttgta
      361 attaatgagc ttaaagaaat atttacaata gaaatcaaat tttagaatta actttattgt
      421 aaaatcaata acttaatcta agaatatctt aatttttata ttttatatag aacaaagttt
      481 acatatttat ttcagacaac gtctttattc aatcgaagag caaattaatc aactgagtgt
      541 cttcaattta aaatgttagg aagtgaatgt atatgaaaac ctaagtagat attagtatat
      601 tttataaata gaaaggagga tatataaaag agttttatca tttagatgta aaaatattat
      661 agtaaaggag aaaattttat gagtttagtt aatagaaaac agttagaaaa aatggcaaat
      721 gtaagatttc gtactcaaga agatgaatat gttgcaatat tggatgcttt agaagaatat
      781 cataatatgt cagagaatac tgtagtcgaa aaatatttaa aattaaaaga tataaatagt
      841 ttaacagata tttatataga tacatataaa aaatctggta gaaataaagc cttaaaaaaa
      901 tttaaggaat atctagttac agaagtatta gagctaaaga ataataattt aactccagtt
      961 gagaaaaatt tacattttgt ttggattgga ggtcaaataa atgacactgc tattaattat
     1021 ataaatcaat ggaaagatgt aaatagtgat tataatgtta atgtttttta tgatagtaat
     1081 gcatttttga taaacacatt gaaaaaaact gtagtagaat cagcaataaa tgatacactt
     1141 gaatcattta gagaaaactt aaatgaccct agatttgact ataataaatt cttcagaaaa
     1201 cgtatggaaa taatttatga taaacagaaa aatttcataa actactataa agctcaaaga
     1261 gaagaaaatc ctgaacttat aattgatgat attgtaaaga catatctttc aaatgagtat
     1321 tcaaaggaga tagatgaact taatacctat attgaagaat ccttaaataa aattacacag
     1381 aatagtggaa atgatgttag aaactttgaa gaatttaaaa atggagagtc attcaactta
     1441 tatgaacaag agttggtaga aaggtggaat ttagctgctg cttctgacat attaagaata
     1501 tctgcattaa aagaaattgg tggtatgtat ttagatgttg atatgttacc aggaatacaa
     1561 ccagacttat ttgagtctat agagaaacct agttcagtaa cagtggattt ttgggaaatg
     1621 acaaagttag aagctataat gaaatacaaa gaatatatac cagaatatac ctcagaacat
     1681 tttgacatgt tagacgaaga agttcaaagt agttttgaat ctgttctagc ttctaagtca
     1741 gataaatcag aaatattctc atcacttggt gatatggagg catcaccact agaagttaaa
     1801 attgcattta atagtaaggg tattataaat caagggctaa tttctgtgaa agactcatat
     1861 tgtagcaatt taatagtaaa acaaatcgag aatagatata aaatattgaa taatagttta
     1921 aatccagcta ttagcgagga taatgatttt aatactacaa cgaatacctt tattgatagt
     1981 ataatggctg aagctaatgc agataatggt agatttatga tggaactagg aaagtattta
     2041 agagttggtt tcttcccaga tgttaaaact actattaact taagtggccc tgaagcatat
     2101 gcggcagctt atcaagattt attaatgttt aaagaaggca gtatgaatat ccatttgata
     2161 gaagctgatt taagaaactt tgaaatctct aaaactaata tttctcaatc aactgaacaa
     2221 gaaatggcta gcttatggtc atttgacgat gcaagagcta aagctcaatt tgaagaatat
     2281 aaaaggaatt attttgaagg ttctcttggt gaagatgata atcttgattt ttctcaaaat
     2341 atagtagttg acaaggagta tcttttagaa aaaatatctt cattagcaag aagttcagag
     2401 agaggatata tacactatat tgttcagtta caaggagata aaattagtta tgaagcagca
     2461 tgtaacttat ttgcaaagac tccttatgat agtgtactat ttcagaaaaa tatagaagat
     2521 tcagaaattg catattatta taatcctgga gatggtgaaa tacaagaaat agacaagtat
     2581 aaaattccaa gtataatttc tgatagacct aagattaaat taacatttat tggtcatggt
     2641 aaagatgaat ttaatactga tatatttgca ggttttgatg tagattcatt atccacagaa
     2701 atagaagcag caatagattt agctaaagag gatatttctc ctaagtcaat agaaataaat
     2761 ttattaggat gtaatatgtt tagctactct atcaacgtag aggagactta tcctggaaaa
     2821 ttattactta aagttaaaga taaaatatca gaattaatgc catctataag tcaagactct
     2881 attatagtaa gtgcaaatca atatgaagtt agaataaata gtgaaggaag aagagaatta
     2941 ttggatcatt ctggtgaatg gataaataaa gaagaaagta ttataaagga tatttcatca
     3001 aaagaatata tatcatttaa tcctaaagaa aataaaatta cagtaaaatc taaaaattta
     3061 cctgagctat ctacattatt acaagaaatt agaaataatt ctaattcaag tgatattgaa
     3121 ctagaagaaa aagtaatgtt aacagaatgt gagataaatg ttatttcaaa tatagatacg
     3181 caaattgttg aggaaaggat tgaagaagct aagaatttaa cttctgactc tattaattat
     3241 ataaaagatg aatttaaact aatagaatct atttctgatg cactatgtga cttaaaacaa
     3301 cagaatgaat tagaagattc tcattttata tcttttgagg acatatcaga gactgatgag
     3361 ggatttagta taagatttat taataaagaa actggagaat ctatatttgt agaaactgaa
     3421 aaaacaatat tctctgaata tgctaatcat ataactgaag agatttctaa gataaaaggt
     3481 actatatttg atactgtaaa tggtaagtta gtaaaaaaag taaatttaga tactacacac
     3541 gaagtaaata ctttaaatgc tgcatttttt atacaatcat taatagaata taatagttct
     3601 aaagaatctc ttagtaattt aagtgtagca atgaaagtcc aagtttacgc tcaattattt
     3661 agtactggtt taaatactat tacagatgca gccaaagttg ttgaattagt atcaactgca
     3721 ttagatgaaa ctatagactt acttcctaca ttatctgaag gattacctat aattgcaact
     3781 attatagatg gtgtaagttt aggtgcagca atcaaagagc taagtgaaac gagtgaccca
     3841 ttattaagac aagaaataga agctaagata ggtataatgg cagtaaattt aacaacagct
     3901 acaactgcaa tcattacttc atctttgggg gtagctagtg gatttagtat acttttagtt
     3961 cctttagcag gaatttcagc aggtatacca agcttagtaa acaatgaact tgtacttcga
     4021 gataaggcaa caaaggttgt agattatttt aaacatgttt cattagttga aactgaagga
     4081 gtatttactt tattagatga taaaataatg atgccacaag atgatttagt gatatcagaa
     4141 atagatttta ataataattc aatagtttta ggtaaatgtg aaatctggag aatggaaggt
     4201 ggttcaggtc atactgtaac tgatgatata gatcacttct tttcagcacc atcaataaca
     4261 tatagagagc cacacttatc tatatatgac gtattggaag tacaaaaaga agaacttgat
     4321 ttgtcaaaag atttaatggt attacctaat gctccaaata gagtatttgc ttgggaaaca
     4381 ggatggacac caggtttaag aagcttagaa aatgatggca caaaactgtt agaccgtata
     4441 agagataact atgaaggtga gttttattgg agatattttg cttttatagc tgatgcttta
     4501 ataacaacat taaaaccaag atatgaagat actaatataa gaataaattt agatagtaat
     4561 actagaagtt ttatagttcc aataataact acagaatata taagagaaaa attatcatat
     4621 tctttctatg gttcaggagg aacttatgca ttgtctcttt ctcaatataa tatgggtata
     4681 aatatagaat taagtgaaag tgatgtttgg attatagatg ttgataatgt tgtgagagat
     4741 gtaactatag aatctgataa aattaaaaaa ggtgatttaa tagaaggtat tttatctaca
     4801 ctaagtattg aagagaataa aattatctta aatagccatg agattaattt ttctggtgag
     4861 gtaaatggaa gtaatggatt tgtttcttta acattttcaa ttttagaagg aataaatgca
     4921 attatagaag ttgatttatt atctaaatca tataaattac ttatttctgg cgaattaaaa
     4981 atattgatgt taaattcaaa tcatattcaa cagaaaatag attatatagg attcaatagc
     5041 gaattacaga aaaatatacc atatagcttt gtagatagtg aaggaaaaga gaatggtttt
     5101 attaatggtt caacaaaaga aggtttattt gtatctgaat tacctgatgt agttcttata
     5161 agtaaggttt atatggatga tagtaagcct tcatttggat attatagtaa taatttgaaa
     5221 gatgtcaaag ttataactaa agataatgtt aatatattaa caggttatta tcttaaggat
     5281 gatataaaaa tctctctttc tttgactcta caagatgaaa aaactataaa gttaaatagt
     5341 gtgcatttag atgaaagtgg agtagctgag attttgaagt tcatgaatag aaaaggtaat
     5401 acaaatactt cagattcttt aatgagcttt ttagaaagta tgaatataaa aagtattttc
     5461 gttaatttct tacaatctaa tattaagttt atattagatg ctaattttat aataagtggt
     5521 actacttcta ttggccaatt tgagtttatt tgtgatgaaa atgataatat acaaccatat
     5581 ttcattaagt ttaatacact agaaactaat tatactttat atgtaggaaa tagacaaaat
     5641 atgatagtgg aaccaaatta tgatttagat gattctggag atatatcttc aactgttatc
     5701 aatttctctc aaaagtatct ttatggaata gacagttgtg ttaataaagt tgtaatttca
     5761 ccaaatattt atacagatga aataaatata acgcctgtat atgaaacaaa taatacttat
     5821 ccagaagtta ttgtattaga tgcaaattat ataaatgaaa aaataaatgt taatatcaat
     5881 gatctatcta tacgatatgt atggagtaat gatggtaatg attttattct tatgtcaact
     5941 agtgaagaaa ataaggtgtc acaagttaaa ataagattcg ttaatgtttt taaagataag
     6001 actttggcaa ataagctatc ttttaacttt agtgataaac aagatgtacc tgtaagtgaa
     6061 ataatcttat catttacacc ttcatattat gaggatggat tgattggcta tgatttgggt
     6121 ctagtttctt tatataatga gaaattttat attaataact ttggaatgat ggtatctgga
     6181 ttaatatata ttaatgattc attatattat tttaaaccac cagtaaataa tttgataact
     6241 ggatttgtga ctgtaggcga tgataaatac tactttaatc caattaatgg tggagctgct
     6301 tcaattggag agacaataat tgatgacaaa aattattatt tcaaccaaag tggagtgtta
     6361 caaacaggtg tatttagtac agaagatgga tttaaatatt ttgccccagc taatacactt
     6421 gatgaaaacc tagaaggaga agcaattgat tttactggaa aattaattat tgacgaaaat
     6481 atttattatt ttgatgataa ttatagagga gctgtagaat ggaaagaatt agatggtgaa
     6541 atgcactatt ttagcccaga aacaggtaaa gcttttaaag gtctaaatca aataggtgat
     6601 tataaatact atttcaattc tgatggagtt atgcaaaaag gatttgttag tataaatgat
     6661 aataaacact attttgatga ttctggtgtt atgaaagtag gttacactga aatagatggc
     6721 aagcatttct actttgctga aaacggagaa atgcaaatag gagtatttaa tacagaagat
     6781 ggatttaaat attttgctca tcataatgaa gatttaggaa atgaagaagg tgaagaaatc
     6841 tcatattctg gtatattaaa tttcaataat aaaatttact attttgatga ttcatttaca
     6901 gctgtagttg gatggaaaga tttagaggat ggttcaaagt attattttga tgaagataca
     6961 gcagaagcat atataggttt gtcattaata aatgatggtc aatattattt taatgatgat
     7021 ggaattatgc aagttggatt tgtcactata aatgataaag tcttctactt ctctgactct
     7081 ggaattatag aatctggagt acaaaacata gatgacaatt atttctatat agatgataat
     7141 ggtatagttc aaattggtgt atttgatact tcagatggat ataaatattt tgcacctgct
     7201 aatactgtaa atgataatat ttacggacaa gcagttgaat atagtggttt agttagagtt
     7261 ggggaagatg tatattattt tggagaaaca tatacaattg agactggatg gatatatgat
     7321 atggaaaatg aaagtgataa atattatttc aatccagaaa ctaaaaaagc atgcaaaggt
     7381 attaatttaa ttgatgatat aaaatattat tttgatgaga agggcataat gagaacgggt
     7441 cttatatcat ttgaaaataa taattattac tttaatgaga atggtgaaat gcaatttggt
     7501 tatataaata tagaagataa gatgttctat tttggtgaag atggtgtcat gcagattgga
     7561 gtatttaata caccagatgg atttaaatac tttgcacatc aaaatacttt ggatgagaat
     7621 tttgagggag aatcaataaa ctatactggt tggttagatt tagatgaaaa gagatattat
     7681 tttacagatg aatatattgc agcaactggt tcagttatta ttgatggtga ggagtattat
     7741 tttgatcctg atacagctca attagtgatt agtgaataga taaaaatatg ttaaatatat
     7801 cctcttatac ttaaatatat aaaaataaac aaaatgatac actacataaa gtgttctatc
     7861 taatatgaag atttaccaat aaaaaggtgg actatgatga atgcacagta gttcaccttt
     7921 ttatatttct aatggtaaca aaatattttt ttatataaac ctaggaggcg ttatgaatat
     7981 gacaatatct tttttatcag agcatatatt tataaagtta gtaattttaa ctatatcatt
     8041 tgatacatta ttaggatgtt taagtgcaat aaaaagtcgt aaatttaatt ctagttttgg
     8101 aatagatgga ggaatcagaa aagtagcaat gatagcatgt atattttttt tatcagtagt
     8161 tgacattctt acaaagttta actttttatt tatgttacca caagattgta tcaatttttt
     8221 aagactaaaa catcttggaa tatctgaatt tttctctatt ttatttattt tatatgaaag
     8281 tgtaagtata ttaaaaaata tgtgcttatg tggattacca gtacctaaga gattaaagga
     8341 aaaaatagca attttactag atgcaatgac agatgaaatg aatgctaagg atgaaaagta
     8401 agtaatggta gatataataa agatattaac aaataaaaag tgttatccaa ataagaatag
     8461 ctgaaagtta tcataattca tgaaactaat aatgaaaacg agggagcaga tgccaagaga
     8521 cacacaagta ttaaatacat ataatttcga agcaagtgtt cattactata tagatgacaa
     8581 ggtagtatat caaacattgg ttcacaaaga tggtgcatgg tcagttggta aaatctatta
     8641 agctacatta gttacagata tcacaaacta taatagttaa acatagaaat atgtgtaaat
     8701 tgtgatggaa attattcaaa aacacaaaaa tacgtgatga aggacaaaat gatatagaaa
     8761 ataagtatca aaccttaata aatgatttaa ttgatagttt aaaagttata ggaaaaatat
     8821 ataaagaaat aaaaacatta aaaaaatata agatatgttt acaaattact atcagacaat
     8881 ctccttatct aatagaagag tcaattaact aattgagtat ctttaaattg aaatgttagg
     8941 aagtgattta aatatgaaaa cttaaattat aaaaaatcaa tattaattta tttttaaaaa
     9001 atagaaagga gtgtataaga tttattttca aagtttaaaa acaagaaaat caatttaaat
     9061 ttcagaagga ataaatgtgg ttatagaagt ggatttatta tcaaaaataa taatactagg
     9121 aggtttttat gtctttaata tctaaagaag agttaataaa actcgcatat agcattagac
     9181 caagagaaaa tgagtataaa actatactaa ctaatttaga cgaatataat aagttaacta
     9241 caaacaataa tgaaaataaa tatttacaat taaaaaaact aaatgaatca attgatgttt
     9301 ttatgaataa atataaaact tcaagcagaa atagagcact ctctaatcta aaaaaagata
     9361 tattaaaaga agtaattctt attaaaaatt ccaatacaag ccctgtagaa aaaaatttac
     9421 attttgtatg gataggtgga gaagtcagtg atattgctct tgaatacata aaacaatggg
     9481 ctgatattaa tgcagaatat aatattaaac tgtggtatga tagtgaagca ttcttagtaa
     9541 atacactaaa aaaggctata gttgaatctt ctaccactga agcattacag ctactagagg
     9601 aagagattca aaatcctcaa tttgataata tgaaatttta caaaaaaagg atggaattta
     9661 tatatgatag acaaaaaagg tttataaatt attataaatc tcaaatcaat aaacctacag
     9721 tacctacaat agatgatatt ataaagtctc atctagtatc tgaatataat agagatgaaa
     9781 ctgtattaga atcatataga acaaattctt tgagaaaaat aaatagtaat catggtatag
     9841 atatcagggc taatagtttg tttacagaac aagagttatt aaatatttat agtcaggagt
     9901 tgttaaatcg tggaaattta gctgcagcat ctgacatagt aagattatta gccctaaaaa
     9961 attttggcgg agtatattta gatgttgata tgcttccagg tattcactct gatttattta
    10021 aaacaatatc tagacctagc tctattggac tagaccgttg ggaaatgata aaattagagg
    10081 ctattatgaa gtataaaaaa tatataaata attatacatc agaaaacttt gataaacttg
    10141 atcaacaatt aaaagataat tttaaactca ttatagaaag taaaagtgaa aaatctgaga
    10201 tattttctaa attagaaaat ttaaatgtat ctgatcttga aattaaaata gctttcgctt
    10261 taggcagtgt tataaatcaa gccttgatat caaaacaagg ttcatatctt actaacctag
    10321 taatagaaca agtaaaaaat agatatcaat ttttaaacca acaccttaac ccagccatag
    10381 agtctgataa taacttcaca gatactacta aaatttttca tgattcatta tttaattcag
    10441 ctaccgcaga aaactctatg tttttaacaa aaatagcacc atacttacaa gtaggtttta
    10501 tgccagaagc tcgctccaca ataagtttaa gtggtccagg agcttatgcg tcagcttact
    10561 atgatttcat aaatttacaa gaaaatacta tagaaaaaac tttaaaagca tcagatttaa
    10621 tagaatttaa attcccagaa aataatctat ctcaattgac agaacaagaa ataaatagtc
    10681 tatggagctt tgatcaagca agtgcaaaat atcaatttga gaaatatgta agagattata
    10741 ctggtggatc tctttctgaa gacaatgggg tagactttaa taaaaatact gccctcgaca
    10801 aaaactattt attaaataat aaaattccat caaacaatgt agaagaagct ggaagtaaaa
    10861 attatgttca ttatatcata cagttacaag gagatgatat aagttatgaa gcaacatgca
    10921 atttattttc taaaaatcct aaaaatagta ttattataca acgaaatatg aatgaaagtg
    10981 caaaaagcta ctttttaagt gatgatggag aatctatttt agaattaaat aaatatagga
    11041 tacctgaaag attaaaaaat aaggaaaaag taaaagtaac ctttattgga catggtaaag
    11101 atgaattcaa cacaagcgaa tttgctagat taagtgtaga ttcactttcc aatgagataa
    11161 gttcattttt agataccata aaattagata tatcacctaa aaatgtagaa gtaaacttac
    11221 ttggatgtaa tatgtttagt tatgatttta atgttgaaga aacttatcct gggaagttgc
    11281 tattaagtat tatggacaaa attacttcca ctttacctga tgtaaataaa aattctatta
    11341 ctataggagc aaatcaatat gaagtaagaa ttaatagtga gggaagaaaa gaacttctgg
    11401 ctcactcagg taaatggata aataaagaag aagctattat gagcgattta tctagtaaag
    11461 aatacatttt ttttgattct atagataata agctaaaagc aaagtccaag aatattccag
    11521 gattagcatc aatatcagaa gatataaaaa cattattact tgatgcaagt gttagtcctg
    11581 atacaaaatt tattttaaat aatcttaagc ttaatattga atcttctatt ggtgattaca
    11641 tttattatga aaaattagag cctgttaaaa atataattca caattctata gatgatttaa
    11701 tagatgagtt caatctactt gaaaatgtat ctgatgaatt atatgaatta aaaaaattaa
    11761 ataatctaga tgagaagtat ttaatatctt ttgaagatat ctcaaaaaat aattcaactt
    11821 actctgtaag atttattaac aaaagtaatg gtgagtcagt ttatgtagaa acagaaaaag
    11881 aaattttttc aaaatatagc gaacatatta caaaagaaat aagtactata aagaatagta
    11941 taattacaga tgttaatggt aatttattgg ataatataca gttagatcat acttctcaag
    12001 ttaatacatt aaacgcagca ttctttattc aatcattaat agattatagt agcaataaag
    12061 atgtactgaa tgatttaagt acctcagtta aggttcaact ttatgctcaa ctatttagta
    12121 caggtttaaa tactatatat gactctatcc aattagtaaa tttaatatca aatgcagtaa
    12181 atgatactat aaatgtacta cctacaataa cagaggggat acctattgta tctactatat
    12241 tagacggaat aaacttaggt gcagcaatta aggaattact agacgaacat gacccattac
    12301 taaaaaaaga attagaagct aaggtgggtg ttttagcaat aaatatgtca ttatctatag
    12361 ctgcaactgt agcttcaatt gttggaatag gtgctgaagt tactattttc ttattaccta
    12421 tagctggtat atctgcagga ataccttcat tagttaataa tgaattaata ttgcatgata
    12481 aggcaacttc agtggtaaac tattttaatc atttgtctga atctaaaaaa tatggccctc
    12541 ttaaaacaga agatgataaa attttagttc ctattgatga tttagtaata tcagaaatag
    12601 attttaataa taattcgata aaactaggaa catgtaatat attagcaatg gaggggggat
    12661 caggacacac agtgactggt aatatagatc actttttctc atctccatct ataagttctc
    12721 atattccttc attatcaatt tattctgcaa taggtataga aacagaaaat ctagattttt
    12781 caaaaaaaat aatgatgtta cctaatgctc cttcaagagt gttttggtgg gaaactggag
    12841 cagttccagg tttaagatca ttggaaaatg acggaactag attacttgat tcaataagag
    12901 atttataccc aggtaaattt tactggagat tctatgcttt tttcgattat gcaataacta
    12961 cattaaaacc agtttatgaa gacactaata ttaaaattaa actagataaa gatactagaa
    13021 acttcataat gccaactata actactaacg aaattagaaa caaattatct tattcatttg
    13081 atggagcagg aggaacttac tctttattat tatcttcata tccaatatca acgaatataa
    13141 atttatctaa agatgattta tggatattta atattgataa tgaagtaaga gaaatatcta
    13201 tagaaaatgg tactattaaa aaaggaaagt taataaaaga tgttttaagt aaaattgata
    13261 taaataaaaa taaacttatt ataggcaatc aaacaataga tttttcaggc gatatagata
    13321 ataaagatag atatatattc ttgacttgtg agttagatga taaaattagt ttaataatag
    13381 aaataaatct tgttgcaaaa tcttatagtt tgttattgtc tggggataaa aattatttga
    13441 tatccaattt atctaatact attgagaaaa tcaatacttt aggcctagat agtaaaaata
    13501 tagcgtacaa ttacactgat gaatctaata ataaatattt tggagctata tctaaaacaa
    13561 gtcaaaaaag cataatacat tataaaaaag acagtaaaaa tatattagaa ttttataatg
    13621 acagtacatt agaatttaac agtaaagatt ttattgctga agatataaat gtatttatga
    13681 aagatgatat taatactata acaggaaaat actatgttga taataatact gataaaagta
    13741 tagatttctc tatttcttta gttagtaaaa atcaagtaaa agtaaatgga ttatatttaa
    13801 atgaatccgt atactcatct taccttgatt ttgtgaaaaa ttcagatgga caccataata
    13861 cttctaattt tatgaattta tttttggaca atataagttt ctggaaattg tttgggtttg
    13921 aaaatataaa ttttgtaatc gataaatact ttacccttgt tggtaaaact aatcttggat
    13981 atgtagaatt tatttgtgac aataataaaa atatagatat atattttggt gaatggaaaa
    14041 catcgtcatc taaaagcact atatttagcg gaaatggtag aaatgttgta gtagagccta
    14101 tatataatcc tgatacgggt gaagatatat ctacttcact agatttttcc tatgaacctc
    14161 tctatggaat agatagatat atcaataaag tattgatagc acctgattta tatacaagtt
    14221 taataaatat taataccaat tattattcaa atgagtacta ccctgagatt atagttctta
    14281 acccaaatac attccacaaa aaagtaaata taaatttaga tagttcttct tttgagtata
    14341 aatggtctac agaaggaagt gactttattt tagttagata cttagaagaa agtaataaaa
    14401 aaatattaca aaaaataaga atcaaaggta tcttatctaa tactcaatca tttaataaaa
    14461 tgagtataga ttttaaagat attaaaaaac tatcattagg atatataatg agtaatttta
    14521 aatcatttaa ttctgaaaat gaattagata gagatcattt aggatttaaa ataatagata
    14581 ataaaactta ttactatgat gaagatagta aattagttaa aggattaatc aatataaata
    14641 attcattatt ctattttgat cctatagaat ttaacttagt aactggatgg caaactatca
    14701 atggtaaaaa atattatttt gatataaata ctggagcagc tttaactagt tataaaatta
    14761 ttaatggtaa acacttttat tttaataatg atggtgtgat gcagttggga gtatttaaag
    14821 gacctgatgg atttgaatat tttgcacctg ccaatactca aaataataac atagaaggtc
    14881 aggctatagt ttatcaaagt aaattcttaa ctttgaatgg caaaaaatat tattttgata
    14941 atgactcaaa agcagtcact ggatggagaa ttattaacaa tgagaaatat tactttaatc
    15001 ctaataatgc tattgctgca gtcggattgc aagtaattga caataataag tattatttca
    15061 atcctgacac tgctatcatc tcaaaaggtt ggcagactgt taatggtagt agatactact
    15121 ttgatactga taccgctatt gcctttaatg gttataaaac tattgatggt aaacactttt
    15181 attttgatag tgattgtgta gtgaaaatag gtgtgtttag tacctctaat ggatttgaat
    15241 attttgcacc tgctaatact tataataata acatagaagg tcaggctata gtttatcaaa
    15301 gtaaattctt aactttgaat ggtaaaaaat attactttga taataactca aaagcagtta
    15361 ccggatggca aactattgat agtaaaaaat attactttaa tactaacact gctgaagcag
    15421 ctactggatg gcaaactatt gatggtaaaa aatattactt taatactaac actgctgaag
    15481 cagctactgg atggcaaact attgatggta aaaaatatta ctttaatact aacactgcta
    15541 tagcttcaac tggttataca attattaatg gtaaacattt ttattttaat actgatggta
    15601 ttatgcagat aggagtgttt aaaggaccta atggatttga atattttgca cctgctaata
    15661 cggatgctaa caacatagaa ggtcaagcta tactttacca aaatgaattc ttaactttga
    15721 atggtaaaaa atattacttt ggtagtgact caaaagcagt tactggatgg agaattatta
    15781 acaataagaa atattacttt aatcctaata atgctattgc tgcaattcat ctatgcacta
    15841 taaataatga caagtattac tttagttatg atggaattct tcaaaatgga tatattacta
    15901 ttgaaagaaa taatttctat tttgatgcta ataatgaatc taaaatggta acaggagtat
    15961 ttaaaggacc taatggattt gagtattttg cacctgctaa tactcacaat aataacatag
    16021 aaggtcaggc tatagtttac cagaacaaat tcttaacttt gaatggcaaa aaatattatt
    16081 ttgataatga ctcaaaagca gttactggat ggcaaaccat tgatggtaaa aaatattact
    16141 ttaatcttaa cactgctgaa gcagctactg gatggcaaac tattgatggt aaaaaatatt
    16201 actttaatac taacactttc atagcctcaa ctggttatac aagtattaat ggtaaacatt
    16261 tttattttaa tactgatggt attatgcaga taggagtgtt taaaggacct aatggatttg
    16321 aatactttgc acctgctaat actcataata ataacataga aggtcaagct atactttacc
    16381 aaaataaatt cttaactttg aatggtaaaa aatattactt tggtagtgac tcaaaagcag
    16441 ttaccggatt gcgaactatt gatggtaaaa aatattactt taatactaac actgctgttg
    16501 cagttactgg atggcaaact attaatggta aaaaatacta ctttaatact aacacttcta
    16561 tagcttcaac tggttataca attattagtg gtaaacattt ttattttaat actgatggta
    16621 ttatgcagat aggagtgttt aaaggacctg atggatttga atactttgca cctgctaata
    16681 cagatgctaa caatatagaa ggtcaagcta tacgttatca aaatagattc ctatatttac
    16741 atgacaatat atattatttt ggtaataatt caaaagcggc tactggttgg gtaactattg
    16801 atggtaatag atattacttc gagcctaata cagctatggg tgcgaatggt tataaaacta
    16861 ttgataataa aaatttttac tttagaaatg gtttacctca gataggggtg tttaaagggt
    16921 ctaatggatt tgaatacttt gcacctgcta atacggatgc taacaatata gaaggtcaag
    16981 ctatacgtta tcaaaataga ttcctacatt tacttggaaa aatatattac tttggtaata
    17041 attcaaaagc agttactgga tggcaaacta ttaatggtaa agtatattac tttatgcctg
    17101 atactgctat ggctgcagct ggtggacttt ttgagattga tggtgttata tatttctttg
    17161 gtgttgatgg agtaaaagcc cctgggatat atggctaaaa tatatgtttg ataaaaaatt
    17221 attcctgtgc tactaagaaa ttatttttat ataataaata ttgagattta attaaaagtc
    17281 atgtgttatt gtaatacatg acttttagtt aaaatttttc tatcatttaa taatctatta
    17341 ttcttgacta ttttataata aaattcatat atggaaatat taatactaaa taattaatag
    17401 ttgataaaaa atagataata tgctaaaagc aaaaactaat ttagagcctt gtaactgttt
    17461 atttgcaatt ataaaaacat ctttaaacat attgactata atataaaata ttaactataa
    17521 tacaaaacaa tattaattaa ttttctctac agctatccct ggtatagtta tatttccacc
    17581 catagttgat tcataagtta tagttccagc acttatacct cttatagtta tgtaatcatc
    17641 ctctaatact cttgaaggag ttattgattt tttataacta catagtacaa ccttatcata
    17701 atttccagac acagctaatc ttatttgcac ctcatcacca tcttcaataa cttgaataac
    17761 cttaccttca aattttacct ttttgtactt ataatcatca ggtgttctag ctaattggtc
    17821 ataagtaata ccagtatcat atcctttctt ctcctcttct tcttttttgc gttgttcttc
    17881 agccttttta gcttcttcag cttttttagc ttcttcagct ttacgttgat tttcagcttc
    17941 aatagctttc ttttcgtcgt ctttcatttt gaaccatggt tcagcatcag acaatttgct
    18001 atttaaagtt tctatttctg ttttttgaga atctataact gatgtttggt tagaaatgac
    18061 ctcctcatgg tcttcagaac aagctggtga ggatatattg ccaaaaaaca cgcctaaaat
    18121 aaatgccagt agaagcaata ccctttgtgc tcttaaagaa tttaattatt ttcttagagc
    18181 ttccttttcc ttcattacta aattcgttac catcattttt tttagaaaac ataatacaat
    18241 ctccctttta ttagatatat tttattttaa aagttaaaaa cttaaaataa ctagttgact
    18301 aaaaattata tattcatatt ttcctaaaat atatttcccc taagcataat tttacaaaat
    18361 aaagtaagaa gattcaatat attttgaaaa aataagataa aaatgtcaga ttataatata
    18421 attttcttga aggtgaattt tatatattaa attaaacata aagtatttta tttgtataaa
    18481 actatattat gatgtaatta agtgactcag tgatttagag gtggtaaaat atatatatat
    18541 gaaagagcat aaataaattg atataataaa aaattaaata ttaaatatta actataataa
    18601 aaaaatatct ggtaataggt ataatataaa aagaatatac cagaaagaag gtgaagtatg
    18661 ggagaactac aaaaaattcc aggggtaggg aaagcaacag aaaaatcttt aatcatgtta
    18721 ggatatacaa ctattaaatc acttaaagat gcaaacccag cacaaatgta tgaaaaggaa
    18781 tgtttaatac gtggacagca catagacaga tgtcagttat atgtatacag atgtgcagta
    18841 tattttgcat caactgaaaa tccagaacca gaaaaattaa agtggtggta ttggaaagat
    18901 taaaaaatca aaaaagttag acataaaaaa gagttgaata tccgttttaa ataataaaaa
    18961 ctaatactca actctttttt agtcgtaaat tttatgtaaa tctatttgta tggctaaata
    19021 tacccatcaa taaatgtata aatataccaa tcaacaaatg actaaacata ctacctaaca
    19081 aaggattaaa taaattactt aacaaagcat tctaaaacaa ttaattagaa actgtttctt
    19141 caagccattt tctacattgc tcaatattta ccatagggtc aaaaccttgg tcttttccct
    19201 tatttaaaag catatcacaa gggaaagtat cacattcacc acaatgatta agttccttac
    19261 tttcacagca agttttaacc ttacattctc caccccaaaa tggtttttcc atagttgggc
    19321 aaccagtgca atttacttgt tctttttttg tacaactgtc acaacagaca ccacatcttg
    19381 attcaaacat gttcaaacat cctttccatt atttaaaaat attataaaat gattttagat
    19441 gaatacaaaa gtgcaaatag ttgattttag gtcatctaaa tgttaaacat aaaattatta
    19501 gtactggtaa atttataaaa actattccaa aaatcttttt gaatatttca aaacacaata
    19561 aattacttca aatccctttg aatatatttt acagcattat agattgcttt aaatctcttt
    19621 gaatattcta caagactata gattagttta aatccctttg aatatatttt acaacattat
    19681 agattgtttt aaatctcttt gaatattcta caagactata gattagttta aatccctttg
    19741 aatatttcaa aacaccatag attactttaa atccctttga atattctata acactataaa
    19801 ttacttttaa cttttatata accataaagt ttttatctgg cactttaaat ggagttttat
    19861 atcaaatttg ccttccatcg aataaccaaa cttaatttaa ttacacattc caagagtcaa
    19921 atattcattc aatatatttg ataattctat gttatagcta taattaaata tagattatta
    19981 aagttaaata tttatttaat atattgaatg attttttacc tatatttaat taagtttcat
    20041 tatataatat aaaaattgtt tttgcattaa gttttaatat aatacataat aattttaaat
    20101 aataacatta ttatatattt tttaatttta ggagtatatc tattatatag cgagtagata
    20161 aaacatataa aattcaaata aaagatatat atttttaaat aaaatggata tagatttcaa
    20221 ctaaaaagaa tataaatttc aaaccccaaa atatctagca tttaccatta agaaataaca
    20281 tcattctttc taaaatttct attggcaatt tcagaaaata ctatagtagt aataaatgca
    20341 acacatattg taactatagt gtcattaaca tttaaagcag attgctttat aacccccata
    20401 gcactaccta acatagaata agggaaaaat ataccaacag caggttttgc tactattaat
    20461 cccataccaa atagagaaag gcaaagacta ataccaatag gagttgcaaa acttctaatc
    20521 tttatagaca tgtataattg tatagaagct attgaaatag aaataatcca acctttagca
    20581 atccaaccag tcaattcttt aggtacacta ccagaaaaac caaacatatt tcctgcaact
    20641 atataaaaga taacaaagaa aacttgtgta atagctgtaa gtattgaaac tactgtaagt
    20701 ttagataaaa agatattttt taaattaact ggcagtgtca ttacattatt ccaattatga
    20761 ttcatatgtt caagcctaca aatatatgca caaaagattg cgattaagat aggaaagaaa
    20821 aattccccat aaaaaagact aacttgagtc cataagctgt accattcttt tttgagtatg
    20881 ccttgattta gataaaaatt accagaacca atcaacacac ttataagtgg caaagctaat
    20941 aatacatacc atataaaaga attttttaac tttagaattt ctcccaaaac tgacttcctt
    21001 aacatttaaa tccctcctat acttcttttt ttaataaatg atttcttcca atataataaa
    21061 ttagcattcc aattaagaaa actaaaatcg taatagaaaa attcatatca attctataga
    21121 cagatgaacc taaaacatta tcataagcat aacttaaagg tgataactct aggtaataag
    21181 accatataaa caatctacga ataccttgat aaaacaaacc tgatgtcaaa cctataaaac
    21241 taccaatcat gccaaatgta attgcaatca tttgatttgg aattacagtt gcaatccata
    21301 ggtgtagtgc aatgatagca atacttacaa gaattgttcc taatgtgtat tttaaaagta
    21361 aagatacaga aattgactca ataacccctc taaaatgtcc aaacaacaca atagataaca
    21421 cttgcatcaa tacaggtata gataccaaaa tagcagaaca taaaaattta gataaataaa
    21481 tactatttaa agatgtcaca gaagatttta aaagcttcca tgtatctcct ttatgttcta
    21541 tatcgcttat acgtgatgta attattgata ttaagatagg aaagaataga ccatttaaac
    21601 ttgcaaaact cataaacata taggaatatt caaatccacc taacatatct ggattacgtg
    21661 taatagctct atttgaattt atgatacacc acattatttc aacagctaca aataaaaagg
    21721 tcatcagaat aatcttcttt cttttaagtt tataaaattc tagaccaagg tatttcatta
    21781 taaagtcacc gccttaccag taagttctaa gaatatatct tccaagcttt ttttatgttc
    21841 ttctattcta aatacatcta tatttgaatg gacaagcata ccatttattt tagccacatc
    21901 tgagtctttt aaattttcaa tagtcaagta cccatcttgt ataagtgaca tatatccttt
    21961 agtatttaat agtttttgtg cagatacaac attcttagtt ttgatagcaa tctgactttg
    22021 acctctatta tgaagttctt ttatgctatc ttgaaaaacc agttcgccat gatttattat
    22081 tcctattgat gtggcaattt ggtcaatttc acttaaaaga tggctagaga ttagaacagt
    22141 catcccgtat ttttctggta gagattttat taattctcta atttcctcaa tccctgctgg
    22201 gtcgagtcca tttgtaggtt catcaagtat taataatttg ggaaacttca ttattgccat
    22261 agcaatacca agacgttgct tcatacctaa agaatattga ctaacttttt tatttttttg
    22321 attttctaac cttacaattt ttaatgcttc atttacattt tttttaggta aatctaagag
    22381 tttttgcatt atggtcatgt tttcaagccc tgtaagatga ccatagtatg atggagattc
    22441 tatcaaagaa cctatatctt ttaaaattga tattctattt ttttcattta actctttacc
    22501 taaaatatta atatttcctt gtgtgggttt agcaagtcca agaagcattt taagagtggt
    22561 agattttcca gctccattag gacccaaaaa accatataca gctccttgtg gaactcttag
    22621 gtctatatcc tttactctaa atattttatt gtattccttt gaaagtcttt gtgttctaat
    22681 tatcatttcc atatgtttca tccccttttt taatctgtgc ttattgattc ttttaactta
    22741 tatcagtata ataacttggt tacatttcaa ttagctgaaa tttaccttac aataacctta
    22801 aaagtctatt taggcaaagt tgtgaaaatg ggtatatggt atactaaagg agggtgatga
    22861 ttatggagtc aataaaagat aaaaaaatac ttgtggttga tgaccacaag gaattattaa
    22921 aaatgataga tgaaatcctg agaaaagagg ggtttagtag agtattttta gcatcaagtt
    22981 atgaggaagc tgttagggta tttagaaatg taaagccaga ttgtgcaatt ttagatgttg
    23041 tattgccaga tggagatggt ttttctatta tgagaaaaat tagagagaca tctaaaatac
    23101 cagtgatttt tctctctgca agaggtgaag atgaagatag attgattggt ttgggcttag
    23161 gggctgacga ttatatagta aagccatttt taccaaagga acttacttta aggcttgtgg
    23221 gtatattaaa tcgtgtatat gtgcctatag aagaagagga gttgccagta tttaaactgg
    23281 gagattctgt tgttgtgaat ttaaatagtg catgtgttga gaaagatggg caagagattt
    23341 ctttaacagc taaagagcat tcgttgcttt taaagttgta tgaaaataaa gggagaattg
    23401 ttactaatga ttcactatgt caagccattt ggggagatga tatgtatgga tatgaaaata
    23461 cccttatggt tcatgttaga agggttagag agaagataga aaaaactcca tctacaccta
    23521 aacatcttat tacagtaaga ggtcttggat ataagttgat gattaattaa ttttagatat
    23581 tagaataaaa gaaatcaaga ggagtgattt aattttggat agtgtaaagt acatattgag
    23641 gcgatttata ggttcaagta tcttgatttc attacttttt attgtattaa atatagcagg
    23701 ttttcttctg ttttcatata tgctatttgt atctaaatac tctgataatt tagatacaag
    23761 tgatagcaga gaaataaaat caaacttgat tatgattgaa gataatttga ttttaagaaa
    23821 tggaaagttt attttagatg attctagtaa ggaagtacta cataaaaata aagtttgggc
    23881 aatgttaatt gataacaatg gagatagaat atggggattt gatttaccaa aagaaattcc
    23941 aagtcattat actttgacag atgtagcaaa gttttcaagg ttctttttaa aggactatcc
    24001 tgtgtatgta tgggaacatc caaatggaat attagtaaca ggttatccaa aagacaagta
    24061 cactaagttt aaccttactt atacggttaa ggaaatagaa caatttccta tgttaataat
    24121 aggtatgttt ttggttaatg caatagttac ttttttaata gctctattca taggtttaaa
    24181 aatggtgaaa tctataaaac caattattac tggcataaag cttatgtcaa aaggagaacc
    24241 agtactttta caagaaaaag gaatactaag tgatatttca aaatctatta atactgtatc
    24301 taaagagttg caaatgaaag atgaaaaact taggaagaaa gaggaagcta ggtctaactg
    24361 gattgcagga atatctcatg atataagaac tccactttca atgataattg gatatgctgg
    24421 agaacttgaa gaaagcagta gcctttcaaa tagagaacaa gagcaagtgt ctattatatg
    24481 caatcaaggg attaaaatca gagaattagt aaatgaccta aatttagtgt ctaaacttga
    24541 atataatatg caagcattga attgtgataa gattagagtt tctgcgtttt tgagagagct
    24601 tatttctgag tttataaata ataatttgga taatgacttt tacgttgaat ttgatatact
    24661 aaatgaagat attattatag atgcagataa aaaattatta aaaagggcta ttagtaattt
    24721 aatacaaaat agtataactc ataaccaaca aggatgtaat ataagggtta cctctaagtc
    24781 tgatttagat ttttgctata taattgttga agatgatgga aaaggtatga gtcaagaaag
    24841 aattaatagt ttattaaaga gccaaaatgg actaagtgag gcatatgcca aaggtcaaaa
    24901 tcatggtcta ggtattttga tagtatctgg cattattaat gcacatagag gtaaattaga
    24961 tattacgagc attgatagtc agggactaaa aacaatacta aaattacctc taattaagtg
    25021 atattttata aaataataac agataagaat gaagaatgaa aatattttga aaataatttt
    25081 attctttatt gacaaattaa ctctattaga gtagaataag gataaattct tttcttgtca
    25141 agttttatta aagtaaagag taacttgtgc tttatgcgct tatggctgag ttactcatgg
    25201 tatcaaaatt ttcatagaaa taatattttg gaattattgt aaggttatta aattctttag
    25261 ataattccat tttttttatt ttttagttaa tatttaattt tattattgac aaaaaaattc
    25321 tactaaaata gaattatggt atagtgtttt ttaattttaa gaaaaaatat aatgacatcc
    25381 taaaaaagtt ttaattatac gctgttctgt gtagttataa tagcttctat gtaactattg
    25441 taagtatatt attatagtta tttatttaaa gtacgataaa tgttttaaat tgaagtattt
    25501 tgcgccattg agttctacta aagtagagtt tttgtgtagt atttttagaa ataacatata
    25561 tatatatgta tttatgttga aatatatggg aaatttataa tataattaat gaaaaaattt
    25621 aaactttgta atatataaat aaaaaaactc taaaatagaa ggatataatt atatagaatg
    25681 tttcaattaa acaaggcaaa aactataatc ttaaaattaa cattattctt aagaagtaag
    25741 aaatttaaga agtaaaaagt ttagttataa gtggtagtaa gcaagaaatt taagaagtaa
    25801 aaagtttagt tataagtggt agtaagcaag aaatttagga agtgggaagt ttagttataa
    25861 gtggtagtaa gtaagaaatt taggaagtgg gaagtttagt tataagtagt agtaagtaag
    25921 aaatttagga agtgggaagt ttagttataa gtagtagtaa gtaagaaatt taggaagtag
    25981 gaagtttagt aataatttgt agcaagtaag aaacttagga agtgggaagt ttagtagtaa
    26041 taatttatag caagtaagaa atttaggaag taggaagttt agtaataatt tgtagcaagt
    26101 aagaaattta gaaagtagga agtttagtaa taatttatag caagtaagaa atttagggag
    26161 taggaagttt agtaataatt tatagcaagt aagaaattta gggagtagga agtttagtaa
    26221 taatttgtat caagtaagaa atttagggag taggaagttt agtaataatt tatagcaagt
    26281 aagaaattta gaaagtagga agtttagtaa taatttatag caagtaagaa atttagaaag
    26341 taggaagttt agtagtaatt tatagtaagt aagaaattta gtaagtgaga agtttagtta
    26401 taatttatag taagtaagaa atttagtaag tgagaagttc agtaataagt tgtagtaaat
    26461 aaaaagttta ggaagtagga agttcagtaa taagttgtag taaataaaaa atttaggaag
    26521 taggatttac tgaaatacaa atatttaaaa tcaaagagtt taaaagaaag gagagctact
    26581 ggacaagtat ccaaaataga tagctgagta caaaatattt cataaaatta agcaatataa
    26641 tacaagagaa ttttgacatt atttatatat atttaccgtg tacaaatagc taaatttagg
    26701 attaagattg aaaaatatct tataagtctg agcttatata aatccgtata agatgtattt
    26761 aatcgaaaaa ttttattatg gatattgctt gtctatattc tgagtagcaa ggttttatca
    26821 tgactataaa aaagttgcca caatcagaat taaagataat gaaatttata tggaaatcag
    26881 attccaaagt aacatctaga gatattgttt taggaatgga gcaaaaatat caatggaaac
    26941 aaacgacaac tttgactctt ttatctagat tagtagtaaa aagatttcta aattctcaaa
    27001 agatagataa atatacgcat tatgaagttt taattaaaga aaaggaatac ataggagttg
    27061 agacaagaga tttttttaga aatattcatg attcttctat aaaaagttta ttgttgtcat
    27121 tacatgaaaa tattaatttg agcaaagatg atatcttact tattgaagag tggataaaaa
    27181 atctaaaaga agaggagaaa gacgtataag caaacgtatt tcttatagca tcaatataaa
    27241 gtgtatgtaa gtgtatttat gtaatatatt agtctactta agtaatatga caaatgatta
    27301 taagtggatt atgatactat aatgtgaatc taaataaatt aaataaaaat taatagtgga
    27361 tattctattt aattaaattt aaaaagctac ctttacttat aagtataatt aaggtagctt
    27421 tttaaataga ggtagt
//
LOCUS       DAEPHU010000061        27369 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 01A10CD0081
            SAMN05941466-rid12468953.denovo.061, whole genome shotgun sequence.
ACCESSION   DAEPHU010000061 DAEPHU010000000
VERSION     DAEPHU010000061.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941466
            Sequence Read Archive: SRR6291087
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 27369)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 27369)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068158.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 22:43:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,892
            CDSs (total)                      :: 3,805
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 87
            rRNAs                             :: 8, 1, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 55
            CDSs (without protein)            :: 55
            Pseudo Genes (ambiguous residues) :: 0 of 55
            Pseudo Genes (frameshifted)       :: 21 of 55
            Pseudo Genes (incomplete)         :: 28 of 55
            Pseudo Genes (internal stop)      :: 16 of 55
            Pseudo Genes (multiple problems)  :: 8 of 55
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..27369
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941466-rid12468953.denovo.061"
                     /strain="01A10CD0081"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            complement(258..1118)
                     /locus_tag="KR231_002638"
     CDS             complement(258..1118)
                     /locus_tag="KR231_002638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein-ADP-ribose hydrolase"
                     /protein_id="HBH0005002.1"
                     /translation="MAMKWRDYADDVNLFEDFDKTIKPLTDEQRRKNINTLIAYFSKE
                     VPSKIYNLSNDEIKPRDILRGLLNVYPPKEIAPEILNMLHNLLLIECEERELVDVNDI
                     EEVEEGIAIWRGNITNLRADAIVNAANNKLLGCLQPLHLCVDNEIHSCAGPRLREDCD
                     KIIKKQGHLEYTGDAKITRGYCLPAKFVVHTVGPIVSGGQPSKEQEKQLLHCYKSCLN
                     TIKEIDEIKNIVFCGISTGVFGYPKKEAANLAVSRVRLWLKENPEKNLKVVFNVFTEE
                     EEEKYRRIFK"
     gene            complement(1435..2763)
                     /locus_tag="KR231_002639"
     CDS             complement(1435..2763)
                     /locus_tag="KR231_002639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010963854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-alpha-glucosidase"
                     /protein_id="HBH0005003.1"
                     /translation="MEKFSVVIAGGGSTYTPEIILMLLDNLDRLPLRAIKLYDNDEER
                     QNKVAKACEILIKEKDPNIEYLATTCPKEAYTDVDFCLAHIRVGKLEMRELDEKIPLK
                     HGVVGQETCGPGGIAYGMRSIEGVLENIDYMEKYSPNCWMLNYSNPASIIAEAVRRLR
                     PNSRVINICDMPIGMEHNIARIAGLKSRKHMDIRYFGLNHFGWYTSIKDKKGNELLPK
                     LVEHIKEYGFINGEEGMKNDKKDSWFETNLFTKEIVKTDLTTIPSSYLKYYLFPDYVV
                     NHSDVNYTRANEVIDGREKEVFGSCALIEKQGHSKGSGLKIGIHAEFIVDLATALAFN
                     TQERMLLIVQNNGAIENIQDDAMVEIPCIVGKDGYEPLSIGKIPTFQKGLIEQQLAVE
                     KLVVDAWIEKSYNKLWQALMLSKTVPSATVAKELLDDLIEANKNYWPKLN"
     gene            complement(2911..3240)
                     /locus_tag="KR231_002640"
     CDS             complement(2911..3240)
                     /locus_tag="KR231_002640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HBH0005004.1"
                     /translation="MVPEMEEKVFSIISEAGDAKSDVMMSLKEIKKGDYNKAKHLLNS
                     ASEKIQTASKHHLELLSNAMNSEDSGTDFLVVHSEDHYSNALFAHSLVSELVDIFEMM
                     DPRINKN"
     gene            complement(3264..4553)
                     /locus_tag="KR231_002641"
     CDS             complement(3264..4553)
                     /locus_tag="KR231_002641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBH0005005.1"
                     /translation="MEALQNNLRRFLLPIAQKIEKQRHLQAIKEGMISITPIIIVGSL
                     SMLFMALNNMLPEGSAKTLLSENMDTLLIPNKFTMSLLSIYSAFFIAQALAKKYNLNH
                     VEIGMTAVVAQLVVCGQVVDGVLDTSYLDAQGLFVSILVALLVVDITKFMNDKNLVIR
                     FPKEVPSVVNKSFRNLTPMIVCIMLFTAIAAITKNVSGQPLPAIIMNFLAPAISSVDN
                     VFAVTIILFITQLLWFFGLHGAAITSSIWMPIAATYMAENATLIAAGGDPKYVFTIGF
                     YYGFLQVTGSGITLGLVYLMSRSKCKSFNSMGKVVILPSLFGINEPVIFGTPIVMNPY
                     MFVPFVFGPVLVGALNFMALKVGLVGLPIAEPPGFLPPGVAAFLMTLDWKAIVLVFAS
                     IILMTLIYYPFFKIMEKEELNKNAELATTLDDDSFDF"
     gene            complement(4569..4895)
                     /locus_tag="KR231_002642"
     CDS             complement(4569..4895)
                     /locus_tag="KR231_002642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBH0005006.1"
                     /translation="MNILLVCANGASTGVLVEKMKSFCSEHEKLKTKTINIEATSFEN
                     LKSYIEANDTDVVLVAPQIRFKEDDVVEACKNYKIAVGLIDTKHYGRMDAPSVMKSAI
                     ELYKNR"
     gene            complement(5030..5659)
                     /locus_tag="KR231_002643"
     CDS             complement(5030..5659)
                     /locus_tag="KR231_002643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0005007.1"
                     /translation="MQDKILRDKKANDPWARMTTRNGFSADEIISSFQKAIRRNMVEE
                     ACEFAYELYISSPELEDKLWRRILTISVEDIGMGDPSAVIIINNLNQVRKEYSYADGD
                     RPLFFIHAIRYLCACEKDRSSDLLKNIIIKGFAMGKVPEVMDVALDKHTYRGLEMGRD
                     SFHFLNEASIVIPEKEVDNDYKERYLKILEKYKQEEVIDTAFKFNHWQY"
     gene            complement(5875..8532)
                     /locus_tag="KR231_002644"
     CDS             complement(5875..8532)
                     /locus_tag="KR231_002644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HBH0005008.1"
                     /translation="MIYKKDKVMKVLESSYRENEKGITANQLSEKTGIARNNISTYLN
                     QLFNEGMVTKIKGRPVYYIPANLNLNKNELLDTQSELLGIKKGTKVENKIKKDSFETL
                     IGKEHSLRPIIEKCKVAMLYPTNGLHTIIYGETGVGKSMIARYMYDYSIDSGIRKNKA
                     PFVTFNCADYANNAQLLMGHIFGVEQGAYTGAESSRKGLLEIANGGILFLDEIHRLPA
                     EGQEMLFTFIDKGTFKRLGDATKERESKVLIICATTENPTSTLLDTFNRRIPMKIEIP
                     SLRDRTMIERMELVKNFFKEESKSISISIKVHKEIIKSLLLYDCKNNVGQLQNDIKLA
                     VANGYLRYKRDNKEPVYIEKKYFDKSINEVSDDYREKSIKADEVITHGIEYFVFTSLG
                     EEEVINYNDINIINAVNTNLNKSVEMNIADASLFNNVKFKSMCESIRQIIKEDEEIDI
                     SESIFKSMAIYIKSVLDKSSSTNNIDLNQIRRNNRSEFKTALKIVGIIENEFDLFLSI
                     ETVAYITLFIVQAKQDEQNKIVNNINIIVAMHGETTASSMVKAVGDIIGKCSAISFDM
                     KLDKSYDEVIVDFKNLINNIDNKDVLLFTDMGSLNSFDEIIKKEKKCGVRVIPMVTTL
                     TVLEAVQKANMGLPLNDVYNSITNTRKHYFGTNEIQNKENLSKTIIIASHVSEGVDNK
                     TRKILEEKMSRYLDGIDIISVPYKTEKDLSLNITKLKESSNIVAVINEQRINIRGIDY
                     ISKKDIDKDENINKLKNIIKISIGYDDVVEGLKTSLKSSNYNRIFKDIKYVSDELFLV
                     FNIEKKYDKVIGLMMHLAFMVDGLIGNTREIEKLDKEKTLDYHKSLSKIKDIVSQLDK
                     KYNIEINEKECYQILLILEYAEIIEKDYQ"
     gene            complement(8891..9835)
                     /locus_tag="KR231_002645"
     CDS             complement(8891..9835)
                     /locus_tag="KR231_002645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009527644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH0005009.1"
                     /translation="MNREKILEIKNLKQYFHLDKSTTVKAVDDISFDIYKGEIFGLVG
                     ESGSGKSTTGKTIIRLHESTGGEVIYKGNCISDKKTYKFIKKDVNKSMQIIFQDSTSS
                     LNPRMTIADIISEPLKIQGICKNKTDRMNKVYEMLKLVGLDRSYANKYPSDFSGGQRQ
                     RIGIARALSVDPEFIIADEPIASLDVSIQAQIVNLFKKLQQEKNLTCLFIAHDLSMVR
                     HISDRIGVMYNGKLVELADSNELYNNPIHPYTKSLLSAIPVPDPRYAKSRNRIEYNSN
                     GYDCSNEKSLSWIEVSDGHFVYSSKSEINKYQQNLKVV"
     gene            complement(9828..10853)
                     /locus_tag="KR231_002646"
     CDS             complement(9828..10853)
                     /locus_tag="KR231_002646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH0005010.1"
                     /translation="MEHLLEVNNLSVSFKVEEGEVQAVRNVSFNLKKGETLAIVGESG
                     CGKSVLCKSLMRILPYNGYIKNGEVLLKSSDLVKKSEKEMEDIRGKNISMIFQDPMTS
                     LNPTISIGKQIAEAVIIHQGISKSEAKKRAIELIELVGIDNPEKRFKQFPHHFSGGMR
                     QRIVIAIALACNPDVLIADEPTTALDVTIQAQIIDLIKDLQHKIGLSIIFITHDLGVV
                     ATIADRIAVMYAGKIVEIGTVEDIFYDPRHPYTWGLLGSLPTLDSQDDYLYNIPGMPP
                     NLLNPPKGDAFAIRNKNALKIDYEKEPPMFKINDTHSAATWLLHPDAPEVDVPVRVNC
                     GRVISNE"
     gene            complement(10928..12496)
                     /locus_tag="KR231_002647"
     CDS             complement(10928..12496)
                     /locus_tag="KR231_002647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HBH0005011.1"
                     /translation="MKLKKLKVLSLVMILSLMAGCSSGGDKDKKADTPKDGKVLVYGS
                     NDYTSINPALYEHGEINSLIFNGLTAHDENNKVVPCLAKDWKFDEATNTYTFNLRDDV
                     KWHDGEKFTANDVKFTIETIMNPDNASEIASNYEDITKIDVVNDNTIKITLKAPNTAM
                     LDYLTVGVLPKHALEGKDIATDEFNQKPIGTGPFKLEKWDKGQSITLVKNSDYFVKEP
                     GLDKVVFKIVPDDKAKAMQLKSGELDLAQITPKDMSNFEKDEKNFKVNIMKTADYRGI
                     LYNFNSKFFKDKKAKGLPNALSYAIDRKAIVDSVLLGHGVPAYSPLQMGPYNNPDIEK
                     FEYNPEKAKQEIEKLGWKLGSDGIYEKEGTKLAFEITAGESDQVRVDMAKICAQQLKE
                     IGVDAKAVVVTETDWANQDAHLIGWGSPFDPDDHTYKVFGTDKGANYSAYSNPTIDKI
                     LQKARETEDKDEKLKLYKQFQVEMTKDMPYTFIAYIDAIYVGKPNIKGLTPDTVLGHH
                     GVGVFWNIADWTIE"
     gene            complement(12609..13520)
                     /locus_tag="KR231_002648"
     CDS             complement(12609..13520)
                     /locus_tag="KR231_002648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBH0005012.1"
                     /translation="MKPQYSDFEIVGENYILVAEDEHIETKKTLSKKIKELPYISIII
                     LSIIVIGSVFSSFIMTHEPTYMDLASSNLAPNKTFLFGTDSMGRDIYSMIWYGGKISL
                     FIGLFSTVISTVIGIVYGSISGSASELVDDAMMRFTEIILSIPSILIIIFVQAILGNS
                     NPVSMSIVIGITSWMNISKIVRTEVRQIKNSEYILAAKSMGGGFFYVLKQHLLPNFVA
                     SIMFMVVTNIGAAIGTESTLSFLGIGLPIEIVSWGSMLSLSEEALLSNRWWIILIPGI
                     FLVTTLVCITNIGNYIRKNNNKKSSNL"
     gene            complement(13504..14490)
                     /locus_tag="KR231_002649"
     CDS             complement(13504..14490)
                     /locus_tag="KR231_002649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBH0005013.1"
                     /translation="MLKDILKKLLQFILVMFLLSFIVFYMARLAPGDPLISYYGDGVE
                     RMSTQEKENAMKKLGLDEPIYSQYIKWISNASKGEFGISFKYKQNVTSVINDVYINTI
                     ILGGSGYILTFVLALLLGIFCTLHEDKLIDRIICKLGTITNCIPSFWVALVLILIFSI
                     NLSILPSSGAYSMGEESSILSRISHLILPLTVLILSHLWYYTYMIRNKLLEEIREDYV
                     LLCKAKGLNNRTIVFKHCLRNIMPSYISIMAISIPHILGGTYVVEKVFSYPGLGTLCF
                     ESAKYHDYNMLLVLCLITGALVVFGNMLAQIINNKIDPRMKYDRGDTNEATI"
     gene            14850..15251
                     /locus_tag="KR231_002650"
     CDS             14850..15251
                     /locus_tag="KR231_002650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HBH0005014.1"
                     /translation="MLLKELYSKTMYTVEENFKENGLTHQQIIVIKLIAHNQELTISQ
                     LCDEMSLAKGTVSGIISRLEQIGYIEKFKKSNDKRNTYVKFTTTGFEFATNFKIKMQE
                     SFDDIFKNCDENELSDLVKNLRNILAKVKER"
     gene            15254..15652
                     /locus_tag="KR231_002651"
     CDS             15254..15652
                     /locus_tag="KR231_002651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR03987 family protein"
                     /protein_id="HBH0005015.1"
                     /translation="MNYKLILAIVFITSALIFYTIGVFGERKAKILKKKHVIIFWLGF
                     IFDTLGTFTMSNIANSHTFEVKSALSQNLHSITGLLAIVLMLFHASWATFVLYKDDEE
                     KKKFFHKFSIVVWTIWLVPYFIGMFIGMAG"
     gene            complement(16102..16326)
                     /locus_tag="KR231_002652"
     CDS             complement(16102..16326)
                     /locus_tag="KR231_002652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NifU family protein"
                     /protein_id="HBH0005016.1"
                     /translation="MREKVEKVLEEKIKPVLQRDGGDVELIDVNENGVVLVRLQGACS
                     GCPGATMTIKAIIENVLVSEVPGVTQVLGV"
     gene            complement(16361..17728)
                     /locus_tag="KR231_002653"
     CDS             complement(16361..17728)
                     /locus_tag="KR231_002653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HBH0005017.1"
                     /translation="MKEYIINNVEEIREELIDLSKKIWENPELAFEEKYASSIQKEYL
                     KSKGFKIEEVENLPTGFIASFGEGKPVIGILGEYDALPELSQCVSAERKPLVEGKAGH
                     GCGHNLLGVAGVGAVVSIKKLIEENKFNGTIKYFGCPAEEEGGGKTAMCINGCFDDVD
                     CAFTWHPFDINAPWRGGSLANLSVKFKFKGITAHAAQAPHNGRSALDAVEIMNVGANY
                     LREHVIDSIRMHYVITNGGGRPNVVPGFAESWYFIRGKKAKDAEHVLDRLIKVAQGAA
                     MMTETEMEYKVTDGIYDYIPNQCLTDLVYDNMVFVGCPKNTPEEEEFAKKLCDTLTRE
                     ERLGVATSLQNDKSIVESYIHKEIVDGDKDKGLAGSTDVGDVSYVIPVAQFAMAAWPV
                     GIASHTWQSCSSAGSNIGFSAMINSAKVLACSAYDVFMDTKIIDEAKIEFDKSLDGQK
                     FKPLV"
     gene            complement(17812..19347)
                     /locus_tag="KR231_002654"
     CDS             complement(17812..19347)
                     /locus_tag="KR231_002654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0005018.1"
                     /translation="MLNNLSNININENNLIKNQYSISLLKECLNCKVIDEREVYNIQQ
                     EISLILMDLIKKYTNGQSTSVKTEVAEKLLISIWYAIDAYINKLGDIEKRVVELTAKN
                     VKKVYLGGIEILEEELVRLKDFYKLMMSRKLDTNSIAYNDTLMELSSFFKSYIVKFEA
                     QDVPVSIDYPLALDDMDVKGIYYVKNYIESIDIENRFCNLFKKKDREKLFYDYGVTYK
                     IDCDAILVNLFELIINNCIFSTILGNEVTNLEISKYEYEFLEKQFKNMYNNITEDKVI
                     DSEESNIIELIEVDDSFNTEVDSNLDYNDFEEINREIRINKKITLLLMEAIEVLIKRL
                     SIEDEDVIRYIKKYEKIFIESVLSSIKSNTFKSMVTVSKNKKEHLEDYIVDDESKLDD
                     ESFREIFNEILDSTSIIEKIRIIKENINAKKDFIDILESECLFGEEYLMLFASLSELE
                     LAILGSVVFYEDIRMREINILEFMLNEKTETTLWKIEYIKFMKRQSEDKIYSIEEHMN
                     KIN"
     gene            complement(19370..19804)
                     /locus_tag="KR231_002655"
     CDS             complement(19370..19804)
                     /locus_tag="KR231_002655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0005019.1"
                     /translation="MISPIILSSINQNLKEIERNELLETNIESGDYGLALSESDVKDI
                     INSRDNTLKGYGRIELDIKVTKQLIENIYTSQYTNVDNYLEAINDMQEIFYYLKNETD
                     DKICDDEIIEILGEFYEKFSGNMDNVRGEADEFAKKFKFGEV"
     gene            complement(20064..20975)
                     /locus_tag="KR231_002656"
     CDS             complement(20064..20975)
                     /locus_tag="KR231_002656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453609.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CGNR zinc finger domain-containing protein"
                     /protein_id="HBH0005020.1"
                     /translation="MNKKIELIGNFASDWIRYSDYEYKITEEDELYIVPTEDAVFTMY
                     NPFDVADDIIVDIIRIGQEALQDISKETKEMKLKKEVLEFVKKYGLLGLIYSSVYNRD
                     IVGEERVLMIEKNYITKENILSTDEYVNMFIPFASDEDVYFKKYRRGIDVSKREESPK
                     FFGKRPLILDLVFSKFYTEQLDWIVSFAKDMCKHFNQICVYKNTSNLLTESVTIMSGG
                     FNPQKIGFSISQLDKPIIAWEFDSLKTAIETIYAFAITSEPSSLNKCKYCGKIYIPTN
                     SKSQYCSPSCRNCSNVKKSRSRAKKDK"
     gene            21271..21624
                     /locus_tag="KR231_002657"
     CDS             21271..21624
                     /locus_tag="KR231_002657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GIY-YIG nuclease family protein"
                     /protein_id="HBH0005021.1"
                     /translation="MDRKRELKQLYKEMKFDTGVFIIKNDITKKIYLGKSNDIKSKFN
                     SLKFQLGAGSCMIKELNNEWKKYGEKAFTFEVLELIKHDDNKTEKDYLEELDILEMVW
                     LEKLKEDNTYEIYSI"
     gene            complement(21843..22784)
                     /locus_tag="KR231_002658"
     CDS             complement(21843..22784)
                     /locus_tag="KR231_002658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp25"
                     /protein_id="HBH0005022.1"
                     /translation="MRISKKVLALGISALLLSVSFPTSINALDKIENIQGVDKYETAG
                     LISDKQDFTTAVLINADSTMVDGIAASGLAGVNNAAILLTNKDDIPEATLQRLNRVTK
                     IYVIGGENSISKDVEKMLLMRRMQVIRIDGVDRVDTSYKIAGEIEKIKNSDKMFLVNG
                     FKDEADAVSVASVAYRDGAPIILTKDIPSAEEDTDLDPWFGVSPVPVYAIGGESTLSD
                     YIVSRYRATRIGGVDRYQTNKNVIEKFYNGAKEFYITSGDDLVYALVASPLAKNAPVV
                     LVSNKSDKSILSGASKVTAIGISDKSIIEQCLDAVKK"
     gene            complement(22885..24120)
                     /locus_tag="KR231_002659"
     CDS             complement(22885..24120)
                     /locus_tag="KR231_002659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HBH0005023.1"
                     /translation="MKILHIITQKPNSTGSGIYLSGMIKGFEKIGHKQAVIAGIDVND
                     DVNCFPSEVSFYPVKYNCGELNFPVVGMSDSMPYESTRYKDLNIDMINRLKYQFKVNI
                     DKAMNDFKPELIICHHLYLLTAFVREMVKDIKVMSICHGTCLRQLNTIDLEKEYIIAN
                     IRKLDLIFALHENQKYDIIKTFGVSQSKVVVIGSGYNDDIFYNKNYKIKDDKIKIVFA
                     GKICKSKGLIPFIKAISKLKYSKDLIEVNFAGTGSDIESYNEIVKLASKSPFKMNFLG
                     KLEQRDLAELFNRSQIFVLPSFYEGLPVVVLEALSCGTDVITTDILGVKEWIGSEINN
                     SGKIEYVSLPFMEKEGIPKDEELYDFENNLYNAIDSKIQSLLNNSNKKTSVDMSKKTW
                     DGLAYRINEVILMDELCLI"
     gene            complement(24164..25018)
                     /locus_tag="KR231_002660"
     CDS             complement(24164..25018)
                     /locus_tag="KR231_002660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0005024.1"
                     /translation="MALNIRNYSLLCNQGTAKFNEDVVGINPFGAWVLDGATGLNGKN
                     LVSTESDARWYVQWWNRYLYKNINKEESLKSIINTGIIEVKKEYELRLNGFKVEKLDL
                     PSSSIVVVKFHENKVEYFLLGDCALFIKNGDSKVIKDRSICKFDNTVFDEMSKLSNLE
                     EMAFDEIRTSVMDTIVSNRLKKNTKEGYWILDFDEEAVENSIYGYIEIKKDFQLMLTS
                     DGFTSACDRYNLIKEEELIRIAEKFGIGYIHNKVRDFEDNDYKAVKVPRFKVKDDSSC
                     LYLDIYND"
     gene            complement(25146..26321)
                     /locus_tag="KR231_002661"
     CDS             complement(25146..26321)
                     /locus_tag="KR231_002661"
                     /EC_number="2.1.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazolecarboxamide
                     formyltransferase"
                     /protein_id="HBH0005025.1"
                     /translation="MARELELKYGCNPNQKPSKIYMKNGELPIEVLNGKPGYINFLDA
                     FNSWQLVKELKEATGLPAATSFKHVSPAGAAVGVPLSDTLKQIYFVDDLELSPLACAY
                     AMARGADRMSSYGDFIALSDVCDKETATIIAREVSDGIIAPGYTDEALEILKGKRKGN
                     YNIVKIDENYTPEPIETKDVYGITFEQGRNEILINEDLLKDIPTDNKIFTDSAKRDLI
                     IALITLKYTQSNSVCYAKDGQVIGVGAGQQSRIHCTRLAGNKADTWYLRQHPKVLNLK
                     FKKDIGRPDRDNTIDVYLSDDYMDVLADGIWQNFFEEKPEPLTGEGKRAWLKTLTGVA
                     LGSDAFFPFGDNIERAKRSGVSFIAQPGGSIRDDNVILTCNKYNIVMAFTKNRLFHH"
     gene            complement(26420..27304)
                     /locus_tag="KR231_002662"
     CDS             complement(26420..27304)
                     /locus_tag="KR231_002662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fumarylacetoacetate hydrolase family protein"
                     /protein_id="HBH0005026.1"
                     /translation="MKFVTFCSSNEEKIGVFNSETNSIYEINSLGLSKLYTDMNDFIE
                     NVSTGDLEKIKNNSFENAKCYKLEEVKLCSPIVRPKKDIICLGLNYKDHVNEIPDGVI
                     KNVVMPDYPIYFSKRADKIIGVDDKISLHGDLVEKLDYESELAVIIGKEGINISKEDA
                     YEYIFGYTIVNDISERALQDKHVQWFRGKSLDTHTSMGPCIVHKEEFEHPLKLDISSV
                     VNGEVRQDSNTEYFIFDIPTIINDLSRGMTLKPGDIISTGTPAGVAMGMNPQVYLKHG
                     DIVECKVEGIGVLKNIVD"
BASE COUNT         8733 a         4884 c         2797 g        10955 t
ORIGIN      
        1 ataattataa atttatttct taaactaata caatttttaa aactattttt catatttatt
       61 taccatacaa ttttcctata ttatattttc taagtaatag cataattgat tatactattc
      121 ttataatttc tattatacct acttatttat taaaaataca aattatattt tattaatttt
      181 tactacttgt aaattattat cttatacaat gaatttgtat tatataataa gtatttttag
      241 gattctgtta cataatatta tttaaatatt cttctatatt tctcttcttc ttcttcagta
      301 aacacattaa atacaacttt taaatttttt tcaggatttt cttttagcca tagtctaact
      361 ctacttacag caagattagc tgcctctttt tttggataac caaatacacc tgtagaaatt
      421 ccacaaaaaa caatattttt tatttcatca atttctttta ttgtatttaa acatgattta
      481 taacaatgaa gcagttgctt ttcttgctct ttacttggct gaccaccaga tacaataggt
      541 ccaacagtat gtactacaaa ttttgcaggt aaacaataac ctctagttat cttagcatct
      601 ccagtatatt ctaaatgccc ttgttttttt attattttgt cacaatcttc tctaagtcta
      661 ggacctgcgc atgaatgtat ctcattatcc acgcatagat gtaatggttg taaacaccct
      721 aataacttgt tatttgcagc atttactatt gcatctgctc ttaaattcgt tatattacct
      781 ctccatatgg caatcccttc ctctacttct tctatatcat ttacatctac taactctctt
      841 tcttcacatt caatcaacaa taaattatgt aacatattaa gtatctctgg agcaatttct
      901 tttggtggat atacattcaa aagtcctcta agtatatctc taggcttaat ttcatcattt
      961 gataaattgt atattttaga aggaacttct tttgaaaaat atgcaattaa agtgtttata
     1021 ttttttcttc tttgttcgtc agttagaggc ttgatagttt tatcaaaatc ctcaaataaa
     1081 tttacatcat cagcataatc tctccacttc atagccatct ctccattctt gtattttaga
     1141 cttaaaaata attatgtatt tatgtacata tttatttatt tctataaaca cctacataaa
     1201 tcctgttaaa agtgtaaatt ttttattata caacttctct ggttatttct attgattgat
     1261 agtaaattat tgtacctaaa tttaatccaa ctaacaagta actaaaccta ctttcctaac
     1321 tgcaaaatac actatgtttg ccacttgtat ctcatttgta gataaataaa gtccctacaa
     1381 atacattaac taggctatgt actaaactgt aggaacttta aaaatatatt attcttaatt
     1441 aagttttggc caataatttt tatttgcttc tattaaatca tctagtaatt cttttgcaac
     1501 tgttgcacta ggaactgtct tagatagcat aagtgcttgc cacaatttat tataagactt
     1561 ctcaatccaa gcatcaacta ctaatttttc aactgctaat tgttgttcta ttaaaccttt
     1621 ttggaatgtt ggtattttcc ctattgataa tggttcatac ccgtcttttc caactataca
     1681 tggaatttca accatagcat catcttgtat attttctata gctccattat tttgaactat
     1741 caataacata cgctcctgtg tattaaaagc tagagctgta gctaaatcca ctataaactc
     1801 tgcatgtatt cctatcttaa gcccactgcc cttagaatgt ccttgctttt ctatcaatgc
     1861 acatgaacca aaaacttctt tttctcttcc atcaataact tcattggcac gagtataatt
     1921 tacatcagaa tgatttacaa cataatctgg aaatagatag tactttaagt aactacttgg
     1981 tattgtagtt aaatctgttt ttactatttc tttagtaaat aaattagttt caaaccaact
     2041 atctttcttg tcatttttca ttccttcttc accatttata aaaccatatt cttttatatg
     2101 ttctactaat tttggtaaaa gttcatttcc ttttttatct ttaattgaag tataccaacc
     2161 aaagtgattt aatccaaagt atcttatatc catatgttta cgagatttga gtcctgcaat
     2221 ccttgctata ttatgttcca tacctattgg catatcacaa atatttatta ccctagaatt
     2281 aggtctcaac cttctaacag cttccgctat tattgatgct ggattagaat aatttaacat
     2341 ccaacaattt ggagaatact tttccatata atctatgttt tcaagaacac cttctataga
     2401 cctcattcca taagctattc cacctggtcc acaagtttct tgaccaacta ccccatgttt
     2461 tagaggtatc ttttcatcta gttctctcat ttcaagtttt ccaactctta tatgagctaa
     2521 acaaaaatct acatctgtat aagcctcttt agggcatgtt gttgctaaat actctatatt
     2581 agggtccttt tcctttatta gtatttcaca agctttagct accttatttt gtctttcttc
     2641 atcattatca tataatttga ttgctcttaa tggtaaccta tctaagttat ctagcaacat
     2701 taatatgatt tctggggtat atgtacttcc tcctccagct attactactg aaaatttttc
     2761 cataataata tctccttttc tatttaaaaa tttactgtat ttataaataa atttataaat
     2821 actagtactt taaagtaaaa gggagttcat ttattaaatc tattgattta ataaactata
     2881 gccaaacttc aagcactatt tacaagaaat ttaattctta ttaattcttg ggtccatcat
     2941 ctcaaatata tctacaagtt cagatactaa agaatgagca aataatgcat ttgaataatg
     3001 gtcttcagag tgcacaacta aaaaatcagt cccactatct tcactattca tagcatttga
     3061 tagtaattct aaatgatgct ttgatgctgt ttgtattttc tctgaggctg aatttaaaag
     3121 gtgttttgct ttattgtagt cacctttttt tatttcctta agagacatca ttacatcact
     3181 tttagcatct cctgcttctg atattatact aaatactttt tcttccattt caggtaccat
     3241 atccttctcc ttctaatgac ttgttaaaaa tcaaagctat catcatctaa tgttgtagct
     3301 aattctgcat ttttatttaa ttcttccttc tccattatct taaagaatgg ataatatatc
     3361 aaggtcataa gtattatact tgcaaatact aatacgattg ccttccaatc taatgtcatc
     3421 aaaaatgctg caacccctgg aggtaaaaag cctggtggtt ctgcaatagg taatcctact
     3481 aatcctactt ttaatgccat aaaattaagt gctccaacca atacaggtcc aaatacaaat
     3541 ggtacaaaca tatatgggtt cataactatt ggtgttccaa atattaccgg ctcatttatt
     3601 ccaaatagtg atggtaaaat cacaactttt cccatactat taaaactctt acacttactt
     3661 cttgacataa ggtacactaa tcccaaagtt attcctgaac cagttacttg caagaaacca
     3721 tagtaaaatc ctattgtaaa cacatatttt gggtctcctc ctgctgctat cagtgttgca
     3781 ttttctgcca tatatgtagc tgctattggc atccatatac ttgaagttat tgctgctcca
     3841 tgaagcccaa agaaccataa taattgagtt ataaatagta ttatagttac tgcaaaaaca
     3901 ttatctacac tgcttatagc tggtgctaag aaattcatta taatagctgg tagtggttga
     3961 cctgagacat ttttagttat tgctgctatt gctgtaaata acattataca tactatcatt
     4021 ggagttaaat ttctaaaact tttatttact acactaggta cttcttttgg aaatctaatt
     4081 acgagatttt tatcattcat aaacttagta atatcaacta ctaaaagtgc tactaatata
     4141 cttacaaata aaccttgtgc atctaaataa cttgtatcta atacaccatc tactacttgt
     4201 ccacatacaa caagttgtgc aacaactgct gtcatgccta tttctacatg attaagatta
     4261 tattttttag ctagtgcctg agctataaaa aatgctgaat atatagataa taaactcata
     4321 gtaaatttat tagggataag taatgtatcc atattttcag ataataatgt ttttgcactt
     4381 ccttcaggta acatattgtt taatgccata aataacatac ttaaagaacc aacaattatt
     4441 attggggtaa tgcttatcat accttctttt atagcttgaa gatgcctttg tttttcaatc
     4501 ttttgtgcta ttggaagaag aaatcttctt aaattatttt gaagtgcttc catttttatt
     4561 ccccccaatt atctattttt atataattcg attgccgact tcataacaga aggagcatcc
     4621 atacgaccat aatgcttagt atctattaaa ccaactgcta ttttgtaatt cttacaagct
     4681 tcaactacat catcttcctt aaacctaatt tgtggtgcta caagtactac atctgtatca
     4741 ttagcttcaa tgtatgattt taaattttca aatgatgttg cctctatatt tatagtttta
     4801 gtttttaact tttcatgctc actacaaaaa cttttcatct tttccacaag tacacctgtt
     4861 gaagctccat ttgcacatac taataaaata ttcataatta ccctcctaca atatctaacc
     4921 tcttttattt tctaattttt tatcagccaa ttcttactct aattcctatc agtttttact
     4981 ttaattctta ttattttatt ttaattctta ttaatattta ctctaattct tagtactgcc
     5041 aatgattaaa cttgaaagcc gtatctataa cttcttcttg cttatatttt tctaatattt
     5101 ttaagtatct ttctttataa tcattatcta cttctttttc tggtattact atactagctt
     5161 catttaaaaa gtggaatgaa tcccttccca tttctaatcc tctatatgta tgcttgtcaa
     5221 gtgccacgtc cataacttct ggaactttac ccattgcaaa tccttttata attatatttt
     5281 ttaataaatc acttgatcta tctttctcac atgcacaaag atatcttatt gcatgtatga
     5341 aaaataaagg tctgtctcca tctgcatatg aatattcctt tcttacttga tttaaattat
     5401 ttatgattat tacagctgat ggatccccca ttcctatatc ttcaactgat attgtaagta
     5461 tccttctcca tagcttatct tctaattctg gtgatgatat atatagttca taagcaaatt
     5521 cacaagcttc ttccaccata tttcttctta tagctttttg aaatgacgat attatttcgt
     5581 ctgcactaaa tccgtttctt gtagtcattc ttgcccatgg gtcatttgcc tttttatctc
     5641 ttaatatttt atcttgcata ttatttactc ctttttattt aaattttaat tatttatatt
     5701 actcatttaa taatataagc aagtattatg ccagtttttt tagacacttt aaaacactgt
     5761 tatttcaatc atttttatca tcaaaactta gatactttgt ctaagtatat ttatatgtgt
     5821 ctaatattaa tattatttta gactaaaaaa aaattaccaa ataagttttt atactcattg
     5881 gtaatctttt tcgattattt ctgcatattc taatattaat aatatttgat agcactcttt
     5941 ttcattaatt tctatattat attttttatc taattgagat actatatctt ttattttgct
     6001 tagactcttg tgataatcaa gtgttttttc tttatcaagc ttttcaattt ctctagtatt
     6061 tccaatcaac ccatctacca tgaaagctaa atgcatcata agtccaatta ctttatcgta
     6121 tttcttttct atattaaata ctaaaaacaa ttcatcagac acatatttta tatctttaaa
     6181 tattctatta taattagagc tttttaagga tgtctttaaa ccttcaacta catcatcata
     6241 acctatactt atctttataa tattttttaa tttattgata ttttcatcct tatctatatc
     6301 ttttttgcta atatagtcaa ttcctctaat attaattctt tgttcattga ttactgcaac
     6361 aatattacta ctttctttaa gtttcgtaat atttaaactt aaatcttttt ctgttttata
     6421 tgggacagat ataatatcta ttccatctaa gtacctactc atcttttctt ctaatatttt
     6481 tcttgtttta ttatctacac cttctgaaac atgtgatgct ataataattg ttttagacag
     6541 attttcttta ttttgaattt cattagttcc aaaatagtgc tttctcgtgt tagtgataga
     6601 gttgtatacg tcatttaaag gtaatcccat attggccttc tgaactgctt ctaacacagt
     6661 taatgtcgtc accataggaa ttactcttac tccacacttt ttttctttct ttataatttc
     6721 atcaaaggag tttaatgaac ccatatctgt aaatagtaat acatctttat tgtctatatt
     6781 attaattaaa tttttaaaat ctacaataac ttcatcatag cttttatcta acttcatatc
     6841 gaaagaaata gcactgcact ttccaataat atcaccaact gcttttacca tactacttgc
     6901 tgtagtttct ccatgcatag caactataat attaatgtta ttcactattt tattttgttc
     6961 atcttgttta gcttgtacta tgaataatgt aatatatgct acagtttcta tagataaaaa
     7021 taaatcaaat tcattttcaa ttattccaac tatttttaat gctgttttaa attcacttct
     7081 gttatttctt ctaatttgat tcaaatctat gttgtttgta gagctacttt tatccaatac
     7141 gctttttata taaattgcca ttgacttaaa tattgattca cttatgtcta tttcttcatc
     7201 ttctttaata atttgtctta ttgattcaca catgctttta aacttaacat tattaaatag
     7261 agaagcatct gctatattca tttctacaga tttattaaga ttagtattta ctgcattaat
     7321 aatatttata tcattgtagt taataacttc ttcttctcct aatgacgtaa atacaaaata
     7381 ttctattcca tgtgttataa cttcatctgc tttaatagac ttctctctat aatcatcact
     7441 cacttcattt atagatttat caaaatattt tttctctata taaactggtt ctttattatc
     7501 tcttttatat cttagatatc catttgcaac agctaatttt atatcatttt gaagttgacc
     7561 tacattattt ttacaatcat aaagtaatag tgatttaatt atttctttat gtacttttat
     7621 tgaaatagaa atactttttg attcttcctt gaaaaaattt ttgactaatt ccattctttc
     7681 aatcattgtc ctatctctca atgatggtat ttctattttc attggtattc ttctattgaa
     7741 tgtatctaat agtgttgatg tcggattttc tgtagtagca catattatta ataccttaga
     7801 ctctctttct ttcgttgcat ctcctagtct tttaaatgtt cccttatcta taaaagtaaa
     7861 caacatttct tgaccttctg ctggtagtct atgaatttca tctaaaaata gtatccctcc
     7921 atttgcaatt tccaaaagac cttttctgga agattctgca cctgtataag ctccttgttc
     7981 taccccaaaa atatgtccca taagtaattg tgcattatta gcataatcag cacaattaaa
     8041 tgttacaaaa ggagctttat tttttctaat tccactatct atagaataat cgtacatata
     8101 tctagcaatc atactctttc ctactcctgt ttctccatag ataatagtat gaagtccatt
     8161 tgtaggatag agcattgcga ccttgcattt ttctattata ggtcttaaac tatgttcttt
     8221 acctattagt gtttcaaaac tatctttttt tattttgttt tctacttttg ttcctttttt
     8281 tatgccaagc aactcacttt gtgtatcaag caattcattc ttgttaaggt taagatttgc
     8341 agggatataa tacacaggtc ttccttttat cttcgtaacc ataccctcat tgaataattg
     8401 gtttaaatat gtacttatat tgtttcttgc aattcctgtc ttttctgata attggttagc
     8461 tgtaatccct ttttcatttt ccctatatga tgattctaaa actttcatta ctttatcttt
     8521 tttatatatc attacaagct cccctacatt atagtatttt attaactaaa acccctatac
     8581 acactttatt ttttaataaa ctcttattct ttaactaagg ttataattta tcaaactttc
     8641 cttactttaa attatagaaa attattgtag aaaaaataag attattgctc attttttcta
     8701 cattactatt tttaatttta tagtactttc ttaacaacat actttacttg tttttaattt
     8761 tattatattt gaatttatta tatttgaaaa gtagaaataa aaaaccctat tttggagtag
     8821 ttttaaaatt tctccaaaaa tagggtttta gtttgtattt caaataaata cctgttcaag
     8881 tatttttata ctaaacaact tttaaatttt gttgatattt atttatttct gatttagaag
     8941 aatatacaaa atgtccatct gaaacctcaa tccaacttaa tgacttttca tttgaacaat
     9001 catatccatt agaattatac tctattctat ttcttgactt agcatatcta gggtcaggaa
     9061 caggaattgc agaaagtagt gattttgtat atggatgaat aggattatta tacaattcat
     9121 ttgaatctgc caattctact aattttccat tatacataac tcctatacgg tcactaatat
     9181 gtctcaccat agataaatca tgagctataa ataaacaagt taaattcttt tcttgttgca
     9241 attttttaaa taaatttact atttgtgctt gtatagacac atccaaagaa gctataggct
     9301 catcagctat tataaattct gggtctactg aaagagctcg tgctatgcca atacgctgtc
     9361 tttgtccacc tgaaaaatca gatggatact tatttgcata acttctatca agtcctacta
     9421 gctttagcat ctcatatact ttattcattc tatctgtttt atttttacag ataccttgaa
     9481 tttttagtgg ctctgaaatt atatctgcaa ttgtcatacg tggatttaat gatgaagtag
     9541 aatcttgaaa aataatctgc atacttttgt ttacatcttt ttttataaat ttgtacgttt
     9601 ttttatctga tatgcaattt cctttgtaaa ttacttctcc accagtagat tcatgtagtc
     9661 ttattatagt tttaccagtt gtagattttc ctgaacccga ctctcctacc aatccaaata
     9721 tctcaccctt atatatatca aaacttatat catcaactgc ttttacagta gtacttttgt
     9781 ccaaatgaaa atattgcttt aagtttttta tttccagtat tttttctcta ttcattagaa
     9841 atcacccttc cacaatttac tctaactggt acatctactt caggtgcatc tgggtgcaat
     9901 aaccaagttg ctgcactatg tgtatcatta attttaaaca ttggtggctc tttttcataa
     9961 tctatcttaa gtgcattttt attccttatt gcaaaagcat ctccttttgg tgggttcaat
    10021 aaatttggag gcattccagg tatattatat aaatagtcat cctgcgaatc taaagtaggt
    10081 aatgaaccca acaaccccca agtatatgga tgtctagggt cataaaatat atcctctaca
    10141 gttcctattt ctacaatctt tcctgcatac ataactgcta ttctatcagc tatagttgca
    10201 actactccta aatcatgagt tataaatatt attgacaaac ctattttatg ttgtaaatcc
    10261 tttattaaat caattatttg agcttgtata gttacatcta aagcagttgt aggttcatca
    10321 gcaatcaata catctggatt acaagcaagt gctatagcta ttactatacg ttgtctcatt
    10381 ccacctgaaa aatgatgtgg aaattgttta aatcttttct caggattatc aattccaacc
    10441 aattcaataa gctctatggc tctctttttt gcctcacttt tacttatacc ttgatgaatg
    10501 attacagctt ctgcaatttg ctttcctatt gatatagttg gattgagaga tgtcataggg
    10561 tcttgaaata tcattgatat attctttcct cttatatctt ccatctcttt ttcagacttc
    10621 ttaaccaaat cacttgattt aagtaaaacc tctccatttt taatatatcc attgtatggg
    10681 agtatcctca tcaaactctt acacagtaca gatttcccac aaccagattc tccaactata
    10741 gccaatgtct cacctttttt tagattaaaa gatacatttc ttacagcctg aacttctcct
    10801 tcttctactt taaaacttac agatagatta ttaacctcca ataaatgttc caaaaaccat
    10861 caacccctat gctattcaaa ccttagggat atatttttat ccctaaggtt tctaattaat
    10921 ttcagtatta ttcaattgtc cagtcagcta tgttccagaa tacacctaca ccatgatgac
    10981 ctaaaactgt atcaggtgtt aatcctttta tgtttggttt tccaacatat attgcatcta
    11041 tataagcaat aaatgtataa ggcatatcct tagtcatttc tacttggaat tgtttatata
    11101 actttaattt ttcatcttta tcttctgttt ctcttgcttt ttgaagtatt ttatctatag
    11161 taggattaga gtaagcactg taatttgcac ctttatctgt tccaaatact ttatatgtat
    11221 ggtcatctgg gtcaaatgga cttccccaac ctattaaatg agcatcttga ttagcccaat
    11281 ctgtttcagt tacaacaaca gctttagcat caacaccaat ttcttttaac tgttgtgcac
    11341 atattttagc catatcaact ctaacttggt cactctcacc tgctgttatc tcgaaagcta
    11401 acttagtacc ttctttttca tagattccat cagaacctaa tttccaacct agcttttcaa
    11461 tttcttgttt agctttttct ggattatatt caaacttttc tatatcagga ttattatatg
    11521 gtcccatttg taaaggtgaa tatgctggta caccatgtcc taataataca ctgtcaacta
    11581 ttgcttttct atctattgca tagcttaaag catttggtaa tcctttagct tttttatctt
    11641 taaagaattt agaattaaaa ttgtataata tacctctata gtcggctgtt ttcattatat
    11701 ttactttaaa attcttttcg tctttttcaa agttagacat atctttagga gttatttgag
    11761 ctaggtctaa ttctcctgat tttaattgca ttgccttagc cttatcatct ggaacaatct
    11821 taaagactac tttatctaat cctggttctt ttacaaaata atcactattc ttaacaagtg
    11881 ttatactttg acctttgtcc catttttcaa gtttaaatgg tccagtacct attggttttt
    11941 gattaaattc atcagtagct atatccttac cctccaaagc atgttttggt aatactccta
    12001 ctgttaaata atcaagcatt gctgtatttg gagcttttaa agtaattttt atagtattat
    12061 cattaaccac atcaattttt gttatatctt cataatttga tgctatctca gaagcattat
    12121 ctggattcat tatagtttct attgtaaact taacatcatt tgctgtaaat ttctctccat
    12181 catgccactt aacatcatct cttaaattaa aagtatatgt atttgttgcc tcatcaaatt
    12241 tccagtcctt tgctagacaa ggaaccacct tattattttc atcatgagct gttaatccat
    12301 taaatattaa cgaatttatt tctccatgtt catatagtgc aggatttata cttgtatagt
    12361 cattacttcc ataaacaagc acctttccat ctttaggcgt atctgccttc ttatctttgt
    12421 ctcctccact agaacaacct gccattagac taagtatcat tactaaactt aaaactttta
    12481 acttctttaa tttcatgatg ctcccccttt tgctttttat aaaatatttt tcaaagcttt
    12541 gaccccattt atttaaatag atatttcaaa tacctcagta tttgcttatt taatactcaa
    12601 atgctgattt ataaattact agatttttta ttattattct ttcttatata attacctata
    12661 tttgttatac acaccaatgt ggtaaccaaa aatatacccg gaatcagtat aatccaccat
    12721 ctatttgaaa gtaatgcttc ctctgacaaa gataacatac ttccccaaga aacaatttct
    12781 attggtaaac caattcctaa aaagctaagt gtcgattcag taccaatagc tgcgcctatg
    12841 tttgttacaa ccatgaacat tattgatgcc acaaaatttg gaagtaaatg ttgctttaat
    12901 acatagaaga atcctcctcc catgctctta gctgctagta tgtattcgct attttttatt
    12961 tgtctaactt ctgttctcac tatcttagat atattcatcc aacttgttat ccctattact
    13021 atggacatag atactggatt tgaatttcca agtatagctt gtacaaatat tataattaat
    13081 attgaaggta tactaagtat gatttctgta aacctcatca ttgcatcatc tacgagttca
    13141 gatgccgaac cacttatact accataaaca attcctataa cagttgatat tacagtggaa
    13201 aatagtccta taaataaaga tatttttcct ccataccata tcatagaata tatatctcta
    13261 cccattgagt ctgttccaaa taaaaaagtt ttatttggag ctaaattaga acttgctaaa
    13321 tccatgtatg ttggttcatg tgtcattata aaagatgaga atacacttcc aatgactatg
    13381 attgataaaa taataattga tatatatggt aattctttaa tttttttaga taaggttttc
    13441 tttgtttcta tatgttcatc ttctgctact aaaatataat tttctcctac aatttcaaaa
    13501 tcactatatt gtggcttcat tagtatcacc tctatcatat ttcattctag ggtctatttt
    13561 attgtttata atttgagcta acatattccc aaatactact aaagcccctg ttattaagca
    13621 taaaactaat aacatattat aatcatgata ctttgcactt tcaaaacaaa gtgttcctaa
    13681 cccaggataa gaaaaaactt tttcaactac ataagttcct cctagtatat gaggtatcga
    13741 aatggccatt atactaatat atgatggcat tatatttctc aggcaatgct taaaaacaat
    13801 agttctatta tttaaacctt ttgctttaca taaaagcaca taatcttctc ttatttcctc
    13861 tagtaattta tttcttatca tatatgtgta ataccataga tggcttaata taagtactgt
    13921 aagaggtaag attagatgtg atatcctact taatatactg gactcttctc ccattgaata
    13981 agcaccacta cttggaagta tacttaagtt tatactaaat ataagtatga gtactaaggc
    14041 aacccaaaat gatggaatac agttggttat tgttcctaat ttgcatatga ttctatcaat
    14101 gagcttatct tcatgtaatg tacaaaatat tcctaacaat aaggctagca caaaggtaag
    14161 tatatatcct gaaccaccta atattatagt gtttatatag acatcattta taacagaagt
    14221 aacattttgt ttatatttaa atgaaattcc aaattcccct tttgatgcat ttgaaatcca
    14281 ttttatatat tgactgtata ttggttcatc caaaccaagt tttttcatag cattttcttt
    14341 ttcttgtgta ctcattcttt ctactccatc cccatagtaa gagattaatg ggtctcctgg
    14401 agcaagtctt gccatgtaaa aaacaataaa agataataaa aacattacta aaataaactg
    14461 caacaacttt ttcagtatat cctttaacaa accccaaccc ccctttgttg caataaaaaa
    14521 aaccacataa aagcaaacgt aaagtaacgt taaaaccttc gtggttccat tatcattaaa
    14581 caaaattaaa ttttctatat ttatctatga gttaatttta gcatcattta ttaactgtgt
    14641 aaacaaactt tttaaaaatt gttaaaattt catcaaatta ttttatttat acctaaaata
    14701 aaatttttat attctattct tcattatttt ctataaaatt ataaaatttt aggttgacta
    14761 tataagaaaa gtatattata ttagtttgta tgcaaaccat ttaagaggtg attttattga
    14821 aaagtaatta tgactgtttt agaatagcca tgctcttaaa agaactttat tctaaaacta
    14881 tgtacacagt agaagaaaat tttaaagaaa atggattaac acaccaacag attatagtta
    14941 taaaactgat agctcataat caagaactta caatatcaca actatgtgat gaaatgtctt
    15001 tagctaaagg tacggtttca ggcataatca gcagattaga acagattgga tatatagaaa
    15061 aattcaagaa atctaatgat aaaagaaata catacgttaa gtttacaaca acaggatttg
    15121 aatttgccac aaattttaaa attaaaatgc aagaaagttt tgatgatatt tttaaaaatt
    15181 gtgatgaaaa cgaattgagt gacttagtaa aaaatcttag aaatatattg gcaaaagtaa
    15241 aggagagata attatgaatt ataaattaat acttgcaata gtatttataa catcagcttt
    15301 aattttctac actataggtg tatttggaga aagaaaggca aaaattttaa aaaagaaaca
    15361 tgtaattata ttttggcttg gttttatatt tgatacttta ggaacattta caatgagtaa
    15421 catagccaac agccatactt ttgaagtaaa atctgcttta tcacaaaacc ttcatagtat
    15481 tacaggtctt cttgcaattg tgcttatgct ttttcatgca agttgggcta cttttgtcct
    15541 atacaaagat gatgaggaaa agaaaaaatt ctttcataag tttagtatag ttgtatggac
    15601 tatatggtta gttccatatt ttataggtat gtttattggt atggctggat agtaaaataa
    15661 aaagtgtgta agaaatactg taggtaaatt tgtataagac aaatttatct acatccttct
    15721 ttcacacttt tacatattta tttataatac tccattattt ctttcatgtt tcttaatacc
    15781 tatatagaat atttaattat ttctatagta ttttattatt ttctcacact ttttcatata
    15841 tatattgttt tactatttct tcatatgtat atatgaaata ttccattatt tctataaatg
    15901 ttttattatc tttctcatac tttttcatat atatattgct tcactatttt ttcttatttc
    15961 ttcatataca tatgaaatat ttcattattt ctataatgtt ttattatctt tctcatactt
    16021 tttcatatat attgcttcac tatttttttt acttctttat taaatactta tgtataacat
    16081 acatttaata aacgctaact attaaacacc taatacttga gttactcctg gaacttcact
    16141 caccaaaaca ttttcaataa tagctttgat tgtcatagtc gctcctggac acccactaca
    16201 tgccccttgt agtctaacta aaaccacacc attttcattt acatctataa gctctacatc
    16261 tccaccatct ctttgtaata ctggttttat cttttcctca agcacttttt caactttttc
    16321 tctcatagct attcccccca gaaatatttt attagcaaaa ttataccaat ggtttaaatt
    16381 tttgtccatc taatgattta tcaaattcaa tttttgcttc atcaataatt ttagtatcca
    16441 taaatacatc ataagcacta caagccagta ctttagctga atttatcata gcagaaaatc
    16501 ctatatttga acctgctgat gaacatgact gccatgtatg acttgcaatt ccaacaggcc
    16561 aagctgccat tgcaaattga gccactggta ttacataact tacatctcca acatcagtag
    16621 aaccagctag tcctttatct ttgtcaccgt caactatttc cttgtgtata tagctttcta
    16681 caatagattt atcattttgt aatgatgttg ctacacctaa tctttcttct ctagtaagag
    16741 tatcacacaa cttttttgca aattcttctt cttcaggagt atttttaggg caaccaacaa
    16801 aaaccatatt gtcataaact aaatcagtca aacattggtt tggtatatag tcatatattc
    16861 catctgtaac cttatactcc atttcagttt ctgtcatcat tgctgctcct tgagctactt
    16921 ttattaatct atcaagaacg tgttctgcat cctttgcttt tttacctcta ataaagtacc
    16981 aactttcagc aaatccagga actacattag gtcttccacc accattagtt ataacatagt
    17041 gcattcttat agagtcaata acatgttctc tcaaataatt agctccaaca ttcataattt
    17101 caacagcatc aagtgcgctt ctaccattat gaggagcttg agctgcatgg gctgttatcc
    17161 ctttaaattt aaattttaca gataagtttg ccagacttcc acctctccaa ggtgcattta
    17221 tatcaaaagg atgccatgta aatgcacaat ctacatcatc aaaacagcca tttatacaca
    17281 tagctgtctt tcctccacct tcttcttcag caggacaacc aaaatatttt attgttccat
    17341 taaatttatt ttcttctatt aattttttta tagaaacaac tgctcctaca cctgctacac
    17401 ccaacaggtt gtgcccacat ccatgtccag cttttccttc taccaatggc tttctttctg
    17461 cacttacaca ttgtgatagc tctggtaaag catcatattc tccaagtatg ccaatcacag
    17521 gtttaccctc tccaaaactt gctataaatc cagtaggtaa attttctact tcttcaattt
    17581 taaatccttt tgactttagg tattcttttt gaatgctact tgcatacttt tcttcaaagg
    17641 ctaattctgg attttcccat attttcttag ataaatcaat taattcttct cttatttctt
    17701 caacattatt tatgatatac tctttcataa ttttcctcca aatatatgta tttttgatat
    17761 gctttacaga ttatattata tactaacatt ctatttattc acaatttttt gttaattaat
    17821 tttattcata tgctcttcta tggagtatat cttatcttca ctttgcctct tcataaattt
    17881 aatgtactct atcttccata aagtagtttc agttttctca tttaacataa attctaatat
    17941 attaatttct ctcattctaa tatcttcata aaatactaca ctacccaata ttgccaattc
    18001 taattcactt aatgatgcaa acaacattaa atactcttct ccaaataaac attcagattc
    18061 aagaatatcg ataaagtctt ttttagcatt gatattttcc tttattattc ttattttttc
    18121 aattatagat gtactatcta atatctcatt gaatatctct ctaaacgatt catcatccaa
    18181 tttactttca tcatcaacaa tataatcttc taagtgttcc tttttatttt tactcacagt
    18241 taccatactt ttaaaagtgt tactttttat tgagcttagc acagattcaa taaatatctt
    18301 ttcatatttt ttaatatatc ttattacatc ttcatcttct atgcttaatc tttttattaa
    18361 tacttcaatt gcttccataa gtagtaaagt tattttttta tttattctaa tttctctgtt
    18421 aatttcttca aaatcattat aatccaaatt actatctact tcagtgttaa aactatcatc
    18481 tacttcaatc aattcaatta tattactttc ttcagagtct ataactttat cttcagtaat
    18541 attattgtac atatttttaa attgtttttc taaaaattca tactcatatt ttgaaatttc
    18601 taaattagtc acttcatttc ctaaaatagt agaaaaaata caattattta taataagttc
    18661 aaataaattt acaagtatag catcacaatc tattttataa gtcaccccat agtcataaaa
    18721 taatttttct ctatcttttt tcttaaatag gttacaaaat ctattttcta tatctatact
    18781 ctcaatataa ttcttcacat aataaatacc cttaacatcc atatcatcta gtgccaatgg
    18841 ataatctata cttactggaa cgtcctgagc ttcaaatttt acaatataac ttttaaagaa
    18901 acttgataac tccatcaagg tatcattata tgctattgaa ttagtatcca attttctact
    18961 catcattagt ttataaaaat cttttagcct aactaactct tcctctaata tttcaatgcc
    19021 tccaaggtac acttttttaa cattcttagc agtcaactcc acaactcttt tttctatatc
    19081 cccaagctta tttatatatg catcaatagc ataccatatt gaaatcaaca gtttttcggc
    19141 aacttctgtt tttactgatg tgctttgacc atttgtatat tttttaatca aatccataag
    19201 tattagagat atttcttgtt gtatattata tacttctctt tcatctatca ctttacaatt
    19261 tagacattcc ttaagtagag atatggaata ttggttcttt attaaattat tttcgtttat
    19321 attaatatta cttaaattat ttaacataca aaatctctcc tatcatatat taaacttctc
    19381 caaatttaaa tttctttgca aattcgtctg cttctcctct tacattgtcc atattgcctg
    19441 aaaatttttc ataaaattca cccagtattt ctataatctc atcatcacat atcttgtcat
    19501 cagtttcatt ttttaaataa taaaaaattt cttgcatatc attaatagcc tctaaataat
    19561 tgtccacatt tgtatattgt gatgtatata tattttctat taactgtttt gtaactttta
    19621 tatctaattc tattcttcca taccccttta aagtattatc tctcgaattt attatatctt
    19681 ttacatcaga ttcagaaaga gctagaccat aatctccaga ttctatatta gtttcaagca
    19741 gttcatttct ttctatttcc tttaaattct gatttataga actcaaaata ataggtgata
    19801 tcatttttaa attctccttt tttatttttt ccattgactt tttttgtttt ttatgctata
    19861 cttaaattaa tttatattat tttaccaacc acttataata gtagtgttaa aagtggtttt
    19921 tgtcaactca aaattactat ctcaattaaa cttttcaatt ttctcaacaa aaaaatacca
    19981 tcatttagat atataacttt ctataacaac ttttaattca gtagttattt actaaaatct
    20041 aaacaatgat atatttatta attttattta tcttttttgg ctctacttct acttttcttt
    20101 acatttgagc aatttctaca agaaggtgaa cagtattgag atttagaatt tgtaggaata
    20161 taaattttac cacagtactt gcatttattt aaagaagaag gttcacttgt aattgcaaag
    20221 gcatagatag tctcaatagc tgttttcaaa gaatcaaact cccatgcaat aattggttta
    20281 tctaattggc ttatagaaaa tcctatcttt tgaggattaa accctccaga cataatagta
    20341 acactttcag ttaatagatt agatgtattt ttatatacac aaatttgatt aaaatgctta
    20401 cacatatctt tagcaaaact tacaatccaa tctagttgtt cagtgtagaa ctttgaaaat
    20461 actaaatcta aaatcaatgg tctctttcca aaaaactttg gagattcttc tctctttgat
    20521 acatctatac cccttctata ctttttaaaa tacacatctt catcacttgc aaatggtata
    20581 aacatgttta catattcatc tgtactcaat atattctctt ttgtaatata attcttttca
    20641 atcatcagta ctctttcttc tccaactata tctctattat atacacttga atatattaaa
    20701 cccaataatc catacttttt tacaaattca agtacttctt tctttagttt catttctttt
    20761 gtctcttttg atatatcttg taatgcctct tgtcctatgc gaattatatc tactattata
    20821 tcatctgcta catcaaatgg gttatacatg gtaaacacag catcttctgt tggaactata
    20881 tataattcat cttcttcagt aattttatat tcataatcac tatacctaat ccaatcactt
    20941 gcaaaattcc ctattaattc tattttttta ttcataataa tcattcacac ctttcaatgt
    21001 aatatataat ttcatattac tattacactt ttagtttatt ccatattttc tacactgtca
    21061 actattcttt ttatattttt agcatattaa aatttataat agcctttata atggatttct
    21121 agagctaaat ttcttgttta ttgatgacta attcataatt aaatttataa aaactattta
    21181 catataaaat taatctcttt ataattgata tgtaatatat ttttacactt acatattaca
    21241 tatcaattat aaagagaggt atctaaaatc atggatagaa aacgtgaatt aaaacaatta
    21301 tacaaagaaa tgaaatttga cacaggtgta ttcataataa aaaatgatat tactaaaaag
    21361 atttaccttg gaaaaagtaa tgacataaaa agcaaattta actctctcaa atttcagctt
    21421 ggtgctggct catgtatgat aaaagaatta aataatgaat ggaaaaaata tggtgaaaaa
    21481 gcatttacat ttgaagtttt agaacttata aaacatgatg ataacaaaac agagaaagat
    21541 tatttagaag aactagatat tttagagatg gtttggttag aaaaattaaa ggaagataat
    21601 acttatgaaa tttattccat ataaaaaatc atataatata agaaaaggag atagtatatc
    21661 aaaatagaca tttagttcat aagatacttt tttatataaa ataaagtatc ttttcataat
    21721 tttaacaatg aaaaagaggc ttatctccat ttgatagcct cttcccatat attttatacc
    21781 attataaaat gaacaatcta ctaattttca atgtgtatat tcattttact aataacactc
    21841 cattacttct ttacagcatc caaacattgc tctataatac tcttatcact tatacctatt
    21901 gctgttactt tactagctcc acttaatata ctcttatcac ttttatttga aactaaaaca
    21961 acaggagcat tttttgcaag tggtgatgca actaaagcat aaactaaatc gtctccactt
    22021 gttatataga actcttttgc tccattatag aacttttcaa taacattttt attagtttga
    22081 tatctatcaa caccaccaat tctagttgct ctatatctgc tcactatgta atcacttaat
    22141 gtagactctc ctccaatagc atatactgga acaggagaaa ctccaaacca tgggtctaag
    22201 tctgtgtctt cttctgctga aggtatatct tttgtcaata ttataggagc tccatctcta
    22261 taagcaacag atgcaacact tactgcatca gcttcatcct taaatccatt tactaaaaac
    22321 atcttatcac tgtttttaat tttttctatt tcacctgcaa ttttataact tgtatctact
    22381 ctatctacac catcaattct tataacttgc attcttctca taagtaacat tttttctaca
    22441 tctttactta tagaattttc tccacctatt acatatatct tagtaactct attcagtctt
    22501 tgaagcgttg cttctggtat atcatcctta ttagttaata aaatagctgc attatttact
    22561 cctgcaagac cacttgcagc aatcccatct accattgtag aatctgcatt gataagaact
    22621 gctgttgtaa aatcttgctt atctgaaata agcccagctg tttcatattt atctactcct
    22681 tgaatatttt caatcttatc tagtgcgttt attgatgttg gaaaactaac acttaacagt
    22741 aatgctgaaa tacctaacgc caataccttt ttactaatcc tcataaatta cctccctaaa
    22801 acaaatatat ttagtattag tataatataa aatcatttaa aaatagtgta aaaatagtta
    22861 cactttttta taatttaaat aattttagat taaacacaat tcatccatta aaataacttc
    22921 atttattcta tatgctaagc catcccacgt tttttttgac atatctacag atgttttctt
    22981 atttgagtta ttcaataaag attgtatctt agaatctatt gcattataca aattattttc
    23041 aaaatcatat aactcttcat cttttggaat accttctttc tccataaaag gtagagaaac
    23101 atattctatc tttccagaat tattaatctc actaccaatc cactctttaa caccaagaat
    23161 atcagtagtg attacatctg tgccacaaga taaagcttct aaaactacaa ctggtaatcc
    23221 ctcataaaat gatggtaaca caaatatttg tgacctgttg aatagctcag ctaaatctct
    23281 ctgttctaac tttcctagga aattcatttt aaatggagac ttacttgcca gtttaactat
    23341 ctcattatat gattcgatat cgcttccagt acctgcaaaa ttgacttcta ttaaatcttt
    23401 actatatttt aatttagata tagcttttat aaatggaatc agtccctttg atttacatat
    23461 cttacctgca aatactattt ttattttatc atcctttatt ttataatttt tattataaaa
    23521 tatatcatca ttataaccac taccaattac aactacttta ctttgactta ctccaaaagt
    23581 ctttataata tcatatttct gattttcatg aagagcaaat attaaatcta atttccttat
    23641 atttgctatt atgtattctt tctctaaatc aatggtattt aactgtctta aacaagttcc
    23701 atgacaaata gacataacct ttatatcttt taccatttcc ctaacaaatg cagttaaaag
    23761 gtacaaatga tgacatatta taagttctgg tttaaaatca ttcatagcct tatctatatt
    23821 tactttaaat tgatatttca atctatttat catgtctata tttaaatctt tatatcttgt
    23881 actttcatat ggcatagaat cactcatacc tacaacagga aaatttaact ccccacaatt
    23941 atactttact ggataaaaac ttacttcact tggaaaacaa tttacatcat catttacatc
    24001 tatacctgca attacagctt gcttatgacc gattttttcg aatcctttta tcataccaga
    24061 caaatatata ccactacctg tactatttgg tttttgtgtt attatatgaa gaattttcac
    24121 ttttcacttg cctcctttct aaaattaaat agttttatac agtctaatca ttatatatat
    24181 ctaaatataa acaagatgaa tcatctttta ctttaaatct tggcacttta accgctttat
    24241 agtcattatc ttcaaaatcc cttactttat tatgtatata tcctatacca aatttttctg
    24301 ctatacgtat caattcttct tcttttatta gattatatct atcacatgca cttgtaaaac
    24361 catcactcgt tagcatcaat tgaaaatctt tttttatttc aatgtatcca tatatagaat
    24421 tttccacagc ttcctcatca aaatccaata tccaatagcc ctcttttgta tttttcttca
    24481 atctattgct tactattgta tccataacac tagttctaat ctcatcaaat gccatctctt
    24541 ccaagttaga aagtttactc atttcatcaa atacagtatt atcaaattta caaatactcc
    24601 tatcttttat aactttggaa tctccatttt taataaacaa agcacaatct cctaataaaa
    24661 aatactctac tttattttca tgaaatttta caacaactat agaactagat ggtaaatcta
    24721 atttttcaac cttaaaccca tttaatctta gttcatactc tttttttact tctattattc
    24781 cagtattaat aatactcttt aatgattctt ctttatttat atttttatat aaatacctat
    24841 tccaccactg aacataccac cttgcgtcac tttcagttga cactaaattt tttccattaa
    24901 gtcctgtagc accatctaaa acccatgccc caaatggatt tataccgact acatcttcat
    24961 taaatttagc tgttccttga ttacataata ggctatagtt tcttatattt aaagccatat
    25021 caacctccaa attgaatatc taaaaataaa gttctattta aaattataca gcaaataaaa
    25081 aaatctacaa caaaacttgt tgtagatttt tacttaatct atattatctt tatactttca
    25141 gtattttaat gatggaataa tctattctta gtaaatgcca tgactatgtt atacttatta
    25201 caagttaata taacattatc atcacgaata gaaccacctg gttgtgctat aaaacttacc
    25261 ccacttcttt ttgcacgttc tatattatct ccaaatggga aaaatgcatc tgaaccaagt
    25321 gctactcctg ttaaagtttt aagccatgct ctttttcctt ctccagttag aggctctggt
    25381 ttttcttcaa aaaagttttg ccatatgcca tcagcaagca catccatata atcatcagaa
    25441 agatatacat caatagtgtt atctctatct ggacgaccta tatccttttt aaattttaag
    25501 tttaatactt taggatgttg acgaagatac caagtatcag ctttgttacc tgcaagtcta
    25561 gtacaatgaa tacgtgattg ttgacctgca cctaccccta ttacttgtcc atctttagca
    25621 taacaaacag aatttgattg tgtatatttt aatgtaataa gagctataat taaatcacgt
    25681 tttgcactat ctgtaaaaat tttattatca gttggaatat cttttaatag gtcttcattt
    25741 attaatattt catttctacc ttgttcaaaa gtaattccat aaacatcctt tgtttcaata
    25801 ggttcaggag tataattttc atctattttt acaatattat agttgccttt acgctttcct
    25861 tttaatattt caagggcttc atctgtatat cctggagcta ttataccatc agaaacctct
    25921 cttgctataa tagttgcagt ctccttatca catacatctg aaagtgctat aaaatcgcca
    25981 taagaagaca ttctatctgc tcctcttgcc attgcataag cacaagctaa tggagaaagc
    26041 tctaaatcat caacaaaata tatttgcttt aaagtatctg ataaaggtac ccctactgct
    26101 gctcctgctg gacttacatg tttaaatgaa gttgctgctg gaagacctgt agcttctttt
    26161 aattccttca caagttgcca actattaaat gcatctaaaa aatttatgta tccaggtttt
    26221 ccatttaata cctctatagg aagttctcca ttcttcatat aaatctttga tggtttttga
    26281 tttggattac agccatactt taattctagt tctcttgcca tatactcatc cctctctata
    26341 ataaattaat cataagtttg attaatccta tattaattaa attattcgta ctaataaaat
    26401 tatatggcat atttatccat taatcaacta tattttttaa aactcctatt ccttcgactt
    26461 tacattcaac tatatcgcca tgctttaaat atacttgagg attcatcccc atagcaaccc
    26521 ctgctggagt tccagttgaa attatatctc ctggctttag agtcattcct cttgataaat
    26581 catttattat agtaggtata tcaaatataa agtactctgt attagaatct tgtcttactt
    26641 ctccatttac tacactactt atatctaatt ttaaaggatg ttcaaattct tctttatgta
    26701 ctatacaagg tcccatagat gtatgtgtgt ctaagctttt tcctctaaac cattgaacat
    26761 gtttatcttg aagtgctctt tcacttatat catttactat tgtatatcca aatatatatt
    26821 cataagcatc ttcttttgat atatttatac cttctttacc tatgattact gcaagttctg
    26881 attcatagtc caacttctct accaaatctc catgtaagct tatcttatca tccactccaa
    26941 ttattttgtc tgctctctta gaaaaataaa ttggataatc tggcataact acgtttttta
    27001 taactccatc tgggatttca ttgacatggt ctttatagtt tagacctaaa catataatat
    27061 cttttttagg tcttacaatt ggggaacata atttaacttc ttctaactta taacactttg
    27121 cgttttcaaa tgaattgttt tttatttttt ctaaatctcc tgtagatacg ttttcaataa
    27181 aatcattcat atcagtatat aatttactta atcctaaact attaatttca tatatactat
    27241 ttgtttctga attaaataca cctatttttt cttcattgct actacaaaaa gtcacaaatt
    27301 tcatttttat tcctccattc aataagttga ttaatattat ttaattttta ttagtttata
    27361 taaattgta
//
LOCUS       DAEPHU010000062        26388 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 01A10CD0081
            SAMN05941466-rid12468953.denovo.062, whole genome shotgun sequence.
ACCESSION   DAEPHU010000062 DAEPHU010000000
VERSION     DAEPHU010000062.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941466
            Sequence Read Archive: SRR6291087
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 26388)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 26388)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068158.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 22:43:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,892
            CDSs (total)                      :: 3,805
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 87
            rRNAs                             :: 8, 1, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 55
            CDSs (without protein)            :: 55
            Pseudo Genes (ambiguous residues) :: 0 of 55
            Pseudo Genes (frameshifted)       :: 21 of 55
            Pseudo Genes (incomplete)         :: 28 of 55
            Pseudo Genes (internal stop)      :: 16 of 55
            Pseudo Genes (multiple problems)  :: 8 of 55
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..26388
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941466-rid12468953.denovo.062"
                     /strain="01A10CD0081"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            25..249
                     /locus_tag="KR231_002663"
     CDS             25..249
                     /locus_tag="KR231_002663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438194.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0005027.1"
                     /translation="MLSTAKKYIEDEKYRIQNSKYELIEDKIEKNYINGYEINSRIEQ
                     ILDYYQCYEINIEIKNEFKKLRFNSYVTRK"
     gene            233..940
                     /locus_tag="KR231_002664"
     CDS             233..940
                     /locus_tag="KR231_002664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0005028.1"
                     /translation="MLLENKGSILIITLIIFSIISTVCIMCIGLIYTHNNMFELGYKD
                     IQLKEISLSGIEISVSNVLSCVEEAIDISNNEDEFREYFLGNNMIECIKKIKDTSYSS
                     LEELSLKVENNTIYDRGDFFEFDIESNVREKEFLKAIKVRVKIKNPWIGIDIEDYMDK
                     SNNNKIDDKTFNNYKASENNEIINQFKNESENIRNQEVVEFTEEDEEELKQNIIENIK
                     KNFDEKNLVQVYKYRGV"
     gene            960..1379
                     /locus_tag="KR231_002665"
     CDS             960..1379
                     /locus_tag="KR231_002665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0005029.1"
                     /translation="MTVIELIVSISIILLIVTLSFPKDNLENHKINLFARQLCSDIRY
                     VRRINMFSNYNTYIYYINQGKHEGYVLRKDGKNIKSIMLPKNAKIARSIEIIKFKSDG
                     SPQKASTIEVYNNRLRKTITITPVSGRVLLKEGKYET"
     gene            1369..1893
                     /locus_tag="KR231_002666"
     CDS             1369..1893
                     /locus_tag="KR231_002666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0005030.1"
                     /translation="MKHKYGYLLLESVVSLSSMVIIILVLYSIFLSTINLKLKVEDKI
                     ELQQQSLEIIKSMEGIISNSMGIMNVSNYEETFKKTTSIKCRYLDENNNEEGISNKEI
                     ILNERRNKLFVNSLNGESSQAGGYEIGDYVDEMYVSITNNGQYVNIKLKLSKCSQKYE
                     TDFKIKVWNFSESI"
     gene            2205..2762
                     /gene="efp"
                     /locus_tag="KR231_002667"
     CDS             2205..2762
                     /gene="efp"
                     /locus_tag="KR231_002667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor P"
                     /protein_id="HBH0005031.1"
                     /translation="MVSAGDFRKGVTFEKDGQPCLVVDFQHVKPGKGAAFVRTKYKNL
                     KTGAIREESFNPSEKFPKAVIDTRQMQYLYNDGELYYFMDQENFEQIPLNYEQVEDAI
                     KFLKENEVATIRFYQGQPFQVEAPNFAELEVTDTEPGIKGDTASNVTKAATVETGAVV
                     QVPLFINTGDKVKIDTRTGEYLSRV"
     gene            2854..3309
                     /locus_tag="KR231_002668"
     CDS             2854..3309
                     /locus_tag="KR231_002668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ribbon domain-containing protein"
                     /protein_id="HBH0005032.1"
                     /translation="MKHLYEEVAYLKGLAEGLEISAESKEGKMIHKIVDALEVFADAI
                     VTLDEEQEELQDFVESIDEDLADLEEDIADMEEDLYEEDDDEDDEDFSYIEMECPNCG
                     ELVEIDEDLLYDDEVDVVCPDCKAVILSSEDDCDDDCTCGGCSSCDDRE"
     gene            3472..4182
                     /locus_tag="KR231_002669"
     CDS             3472..4182
                     /locus_tag="KR231_002669"
                     /EC_number="3.1.26.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease III"
                     /protein_id="HBH0005033.1"
                     /translation="MKISKKLLDNIQRFENVINYKFKNKEYILEALTHSSYSNENKKY
                     NFNERLEFLGDSVLGIVISDYLFNEEANLPEGELTKLRANIVCEDSLSEVANDINLGI
                     HMLLGRGEEATGGRHRTSILADAFEAVIAAIYLDGGFESARQFILHHMENIIYDSRKG
                     NIFRDYKTHLQEVLQGNGENNIWYRLIEEKGPDHNKRFVMEVGINDDVLGIGEGKSKK
                     EAEQLAAKIALKKKLWEK"
     gene            4236..5306
                     /locus_tag="KR231_002670"
     CDS             4236..5306
                     /locus_tag="KR231_002670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM protein"
                     /protein_id="HBH0005034.1"
                     /translation="MKKRIIPIFVPHKGCPHDCIFCNQKKITGVSTDVTSEDARNIIE
                     ECLETIDKDADVEIAFFGGSFTAIDIDIQKSLLSVAKEYVEKGLVKDIRMSTRPDCID
                     EDILSMLKEYKTSIIELGVQSLDEKVLLDSIRGHQSEIVYKSSKMIKNSGIKLGLQMM
                     IGLPADTEEKCIFTAKKFVELKPDCVRVYPTLVVKDTGLEKLMEQNKYNPFTLEESVN
                     IVKKVLVLFYVNNINVIRVGLQATDDIQIGKAVLAGPYHPAFRELVEADMIKDYLEFV
                     ILQNKNIKQMLVKSNKKNISKIIGNKKTNVKYMEEKFGVLLKTQESDLDINQLEIVLD
                     GKSLISANMRDIHRKLYDIYDL"
     gene            5334..8888
                     /gene="smc"
                     /locus_tag="KR231_002671"
     CDS             5334..8888
                     /gene="smc"
                     /locus_tag="KR231_002671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome segregation protein SMC"
                     /protein_id="HBH0005035.1"
                     /translation="MYLKRLELKGFKSFPVKTDIIFKEGITAIVGPNGSGKSNISDAV
                     RWVLGEQSIKSLRGDKLEDVIFAGTDTKKPMNYCEVALTIDNSENQLELDFTEVTIRR
                     RAYRNGESEFFLNNKSCRLKDIKEVFLDTGIGKDGYSIIEQGKVDEILSNNPLSRRKV
                     FDEACGISKYRYKKQEAERNLSNTKENLERIDDVYIEIENQLKPLFNQQTKAKKYLEI
                     SEKLKTLEVNSFIREIEGIEKELSEVNEHRKVIEKELNEKEEQKNVVEKKQEDINKEV
                     EVLQDVIEKSVDYINSIKGVISKKESQINLIKERIRNFTNEISRKNLEINDIKEKLNE
                     NKQYIKELESNKLSGSEELSTLQENIKVLEASKDKQKIKLESLNNEIELLKESIIDIL
                     NKKQEFSNKLSTLNANKENMNIRDENINSEITELNKNIEIKSSELDTINKEFNMQNEN
                     LKNVNNRHKELSTNLQDSISEHNKLEDEIQKSKYNLNGYNSKLNVYIDMENHYEGFNR
                     GVKEVLKNKNLKGVHGALGQIINVPEKYEKSIEAALGAYMQNIITDNEFSAKSAINYL
                     KQNNLGRVTFLPLNIIKSNKISLGNLKANTKFIGIASDLITFDEKYRNIIENILGRTI
                     LINNIDEGIKFAKETGHRFKIVTLDGEILNPGGSLTGGSLKTNGNILSRKRYINEYTE
                     KISNIKNEISHLELKRESLDKDVKNIKNEIDSHESKIKDLEKSIIIKSTSIKNVESEI
                     ESLKGSITKLENEKNDLNSNLNYTLEKSDDVRKDMEELDDLYNKNKEKIDALNEEIKR
                     YNDLYDKEKSEFDELNLSLVKKTEVYNSIVRDIKRISGENCELEEKNKQLEESLNYEE
                     HEIIKLQDSILTEEKEKENLTKQLGDSNRNLETRKIAKDDLKNSFDEINKELKTIDRQ
                     HIELKESLFKVGGRLERLKTSQDTYINKLFEQYDMTLVQALEIKDEDLDIDRKFLESL
                     KREIRSLGNINIDSIKEYEEIKERYDFYSEQKQDLEESMEEIEKLIHTLEENMKSEFE
                     IKFEEISKNFKYVYKRLFGGGCGELTILDKENLLESDILITAQPPGKKMKNLNLLSGG
                     EKALTAISILFAILITKPTPFCILDEIEAPLDDANIFRFGEFLKDLSKETQFISVTHR
                     RGTMEAADYIYGVTMQEKAISKVISLKLKEAQEITDII"
     gene            8915..10195
                     /gene="ftsY"
                     /locus_tag="KR231_002672"
     CDS             8915..10195
                     /gene="ftsY"
                     /locus_tag="KR231_002672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle-docking protein
                     FtsY"
                     /protein_id="HBH0005036.1"
                     /translation="MLKKLFGFGKDKEKEIEKKDAEEEIEVEDSVDNLENLEETIFSG
                     LEEEVIDKVEDVEEKNEESVNNEGTEEIENFEKIEVEMDSNGKEVENISNNDSQEEII
                     EELENYDEIESKEIEDKEDKKVNLFERLKQGLTKAKQGITDRIDEVLKSYTKIDEELL
                     EDLEEILITADVGVNTTMDIIERLRDKIKQKGITEPIKVREELKSIVEDILTNENSTL
                     DIEPVPCIILMVGVNGVGKTTTIGKLANRYKKDGKKVLLAAADTFRAAATEQLEIWAN
                     RTNVDIIKHQEGADPGAVVFDAIKAAKARKTDVLICDTAGRLHNKANLMNELGKVFKI
                     VDREFPEAKREVLLVVDATTGQNAVVQAKTFKEVADITGIVLTKLDGTAKGGVVLAVK
                     SEVDVPVKLIGVGESVEDLQDFNAKSFSDALFGN"
     gene            10298..10666
                     /locus_tag="KR231_002673"
     CDS             10298..10666
                     /locus_tag="KR231_002673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative DNA-binding protein"
                     /protein_id="HBH0005037.1"
                     /translation="MNIEKMVEIGLLFEQYKELLTDKQKEIVALYYEEDYSLGEISEN
                     LNVSRQGVYDTLKRSEKILRDYEEKLHLVSKIQEQEKNIKIIKDKIIDIKEDLLHNRD
                     CANLIPKLENIEDVCREMIK"
     gene            10663..12015
                     /gene="ffh"
                     /locus_tag="KR231_002674"
     CDS             10663..12015
                     /gene="ffh"
                     /locus_tag="KR231_002674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle protein"
                     /protein_id="HBH0005038.1"
                     /translation="MIFEGLSDKLQGAFSKLKSKGKLTEVDVKNAMREVKLALLEADV
                     NFKVVKDFIKKVQERCVGQEVMQSLTPAQHVIKIVNEELTSLMGDVQSKVMISSKPPT
                     ILMMVGLQGAGKTTTAGKLGGYFKKQGKKPLLVACDIYRPAAIKQLQVVGEKLDIPVF
                     NMGDKENPVNIAKAGLSHAIKNANDLVIIDTAGRLHIDEVLMDELKSIKSEVKPHEIL
                     LVVDSMTGQDAVNVAESFNEALGVDGVVLTKLDGDTRGGAALSIRAVTQKPIKFMGMG
                     EKLDDIEPFHPDRMASRILGMGDVLSLIEKAQENIDLEKAKELEQKIKKQELDFEDFL
                     QQMEQIQNMGPLDKILGMIPGMGNVKDQLGDVDLNGKEMKRTKAIIQSMTTYERRNPG
                     VLNASRKKRIAKGSGTSVQDVNRLIKQLNEMKKMMKMFAGSQKSMKKRGGLGGLPFFK
                     "
     gene            12053..12325
                     /gene="rpsP"
                     /locus_tag="KR231_002675"
     CDS             12053..12325
                     /gene="rpsP"
                     /locus_tag="KR231_002675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000268750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S16"
                     /protein_id="HBH0005039.1"
                     /translation="MAVKIRLKRMGANKKPFYRIVVADSRAPRDGKFIEEIGYYNPIS
                     EPKQVRINDEKAIKWLATGAQPTEVVKKLLVKNGVIEKFEASKQAK"
     gene            12390..12617
                     /locus_tag="KR231_002676"
     CDS             12390..12617
                     /locus_tag="KR231_002676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KH domain-containing protein"
                     /protein_id="HBH0005040.1"
                     /translation="MKELVVDIAKALVDNPDSVVVEEFEDNDGIVLKLTVAQEDMGKV
                     IGKQGRIAKAIRTVVRSVANRENIKVSLEIV"
     gene            12725..13240
                     /gene="rimM"
                     /locus_tag="KR231_002677"
     CDS             12725..13240
                     /gene="rimM"
                     /locus_tag="KR231_002677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438220.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA processing protein RimM"
                     /protein_id="HBH0005041.1"
                     /translation="MKEKLTHFKVGQIVNTQGLKGEVRVYPLTDDIERFDELKDFYLG
                     KDLNNKLAVEKVRYKGSMVIMKIKGIDSIEKAEKLKNKFMYVSREDSRELEEGEFFIA
                     DMIGMEVLTVDGKYVGILEDVLQYSANDVYVVKGEEDKEFMIPAIKKFVPTIDIDERK
                     MIIDPIKGMID"
     gene            13249..13944
                     /gene="trmD"
                     /locus_tag="KR231_002678"
     CDS             13249..13944
                     /gene="trmD"
                     /locus_tag="KR231_002678"
                     /EC_number="2.1.1.228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000686892.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(37)-N1)-methyltransferase TrmD"
                     /protein_id="HBH0005042.1"
                     /translation="MRFHIMTLFPEIFNSYMDESIMKRAVEKGIIEVHIYNIRDFSNN
                     KHKKVDDYPFGGGAGMVMTPQPIYDTYKHIITTHNINNPSVIYLTPKGKVYNQSMAKQ
                     MSLKEDIILLCGHYEGIDERIIDLIVTDEISIGDYVLTGGELPALIMIDSISRLIPGV
                     LNQEESFEEESFKDNLLEYPHYTRPRDFEGLKVPEVLLSGNHKKIDEWRREESIRITK
                     ERRFDLYKKSNEK"
     gene            14129..14479
                     /gene="rplS"
                     /locus_tag="KR231_002679"
     CDS             14129..14479
                     /gene="rplS"
                     /locus_tag="KR231_002679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L19"
                     /protein_id="HBH0005043.1"
                     /translation="MNEMLRAIEQEQLKNEVPNFGPGDTVKVHVRIIEGKRERIQVFE
                     GVVLKRQGGGARETFTVRKMSFNVGVERTFPVHSPKIEKIEVTRKGKVRRAKLNYLRG
                     RVGKAAKIKEARNK"
     gene            14800..15696
                     /gene="ylqF"
                     /locus_tag="KR231_002680"
     CDS             14800..15696
                     /gene="ylqF"
                     /locus_tag="KR231_002680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YlqF"
                     /protein_id="HBH0005044.1"
                     /translation="MSNEYEEYLMDDNLHINWYPGHMKKTKELVKNNLKLIDVVIELL
                     DARIPFSSKNPDIDRLVGDKPRVVVLNKSDMADRDKLNQWIEYYKKINIKAIPVDTIK
                     GVGINKIIEECKNVTREKMSSLKDKGRKERAIRIMIVGVPNVGKSSLINKLTGRKSTQ
                     TGDKPGVTKGKQWVRLKGNLELLDTPGILWPKFEDQEVALNLAFSRAIKDEILDTETL
                     ALRLIEKLMKIEPEKLKARYKLDCLGETPIETMDMIGHKRGFITGKKELDYTRIATTV
                     LNEFRDGKIGNITLEVPENVKR"
     gene            16085..17377
                     /gene="brnQ"
                     /locus_tag="KR231_002681"
     CDS             16085..17377
                     /gene="brnQ"
                     /locus_tag="KR231_002681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid transport system II
                     carrier protein"
                     /protein_id="HBH0005045.1"
                     /translation="MGKTKDVIVFGFALFAMFFGAGNLIFPPYLGIITGPEWLIAFLG
                     FTFADAGLALLAVMATAKFDGNVVEMFKRCGMKLGILIGCADILCIGPFLAIPRTGAT
                     TYEMGIMPLFGTSIPVLLFCILFFALSYVLTIRPSKVVDIVGQFLTPALLIALAFIII
                     KGIISPLGDIVDKPMIPNVFAEGIGQGYQTMDAFAAIALASVLIVSLNDKGYSTISDK
                     LKMIGKAGVLACGGLALVYGGLCFLGATVSTMYGTDAVQSQVIVNITEGLLGNVGKAI
                     LAVVVSLACLTTSIGLTSATGQYFSRLTKGKLSYEKIVLAVSVFSAVVASFGVGTIIK
                     IASPILSIVYPPSIVLIILAFFNEKIKNDNVYKGAVYMSLLVSILTVISSYGVAVPVV
                     NSLPLNSLGFNWVVPVIIAGIIGNFIPSKSQSNTLGTN"
     gene            18495..19787
                     /gene="brnQ"
                     /locus_tag="KR231_002682"
     CDS             18495..19787
                     /gene="brnQ"
                     /locus_tag="KR231_002682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid transport system II
                     carrier protein"
                     /protein_id="HBH0005046.1"
                     /translation="MGEKQINFKDVIVIGFALFAMFFGAGNLIFPPYLGVLSGSSWLI
                     AFIGFLFADGGLALLAVIAATKFNGDTSKMFSRAGKGLSIALGCAMVICIGPLLAIPR
                     TAATTYEMGILPTIGSGISPVIFSIVFFALVLVLTIRPSKVVDIVGSILTPALLIALA
                     VLIVKGIISPLGEIRDSSLIQNVFAEGITQGYQTMDALAASVFASIIIMSVIAKGYTG
                     EKEKMKATISAGVIAVIGMALVYGGLCYLGATVSQQYGQDVQQTALIVAITAALLGTT
                     GKILLAIIVALACLTTAIGLSSAAGQYFSTLTDGKLKYEHIVIVVCVFSAIISNFGVS
                     TIIQFSSPILSMVYPATITLVILALFSNKIKNDNVFKCAAYMALLVSVLTVATSFGVK
                     IPLVNSLPFASLGFNWIVPVVIAGIIGNFIPSKSSKTA"
     gene            20361..22550
                     /locus_tag="KR231_002683"
     CDS             20361..22550
                     /locus_tag="KR231_002683"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenosylcobalamin-dependent
                     ribonucleoside-diphosphate reductase"
                     /protein_id="HBH0005047.1"
                     /translation="MKYIIKRDGTKELFSKSKIEDAVYKASINSEGGVDRELAYDISR
                     KIANDYNSMEKCLSVEEIQDIVEVLLMESNRKDIAKHYILYRERRSEIRTKAWEFDEL
                     QKSIWKNKYRHNGESFDEWIKRISNNSSRISKLIRQKRFLFAGRILANRGLQKEGKKV
                     TYSNCYVIEPPKDSIEDIFDTAKKLARTFSYGGGVGIDISKLRPKGAKVNNAAKHTTG
                     AVSFMELYSMTTGLIGQRGRRGALMISMDVNHPEIEDFIDIKTDLEKVTKANISVRVT
                     DEFMQAVREKKLYNCTFEVETTGEKIVKIVNAYDLFNKFVKNNWDYAEPGILFWDKIK
                     TYNFMSEDKNFCFSGVNPCAEEPLPSGGSCLLGSINLSEFIIQPFGEHATFDINKLKS
                     CVREAVVALNDVLDEGLNLHPLQEQRDSVHKYRQIGLGVMGIADMLIKMGIRYGSDES
                     LELCDLIGKTMLNEAVKQSALIAKEYGTFSEYKYENISKSKFFIENLNEDTKEMVKKY
                     GLRNSQLLTIPPTGSISTMIGISGGIEPIFNLSYIRKTESLHDEDVYYKVYTPIVKEY
                     MDKKGITDEECLPDFFVTAMNIGYEERINMQKVWQKYIDASISSTINIPFETTVEDVF
                     NIYIKAWEAGLKGVTIFRDGCKRSGILINEKKEENNKEDKKENSKKEYYKNNKKEKDN
                     KDEKAKEIINKNFEEDEKFVCPECGSEGIAHTGGCSICLKCGYSGCN"
     gene            22618..23385
                     /locus_tag="KR231_002684"
     CDS             22618..23385
                     /locus_tag="KR231_002684"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HII"
                     /protein_id="HBH0005048.1"
                     /translation="MQDKSVREIKEIIETLEVEKYMEYIELLRVDERKSVQGLAIKLA
                     KKLDNIRKEEERLETINIFENEGYDKGYLYIGGIDEAGRGPLAGPVVASVVVFKKDTK
                     IEGVNDSKKLSEAKRDELFEVIKEEALDYGIGIVNNEEIDEFNILNATYMAMKKAINC
                     LKKAPDYLLVDAATIPGIDISQNPIVKGDSKSISIAAASILAKVTRDSIMYQYDRVYP
                     EYGFKSHKGYGTKEHYEAIEKYGITPIHRKSFLKNIL"
     gene            23443..24459
                     /locus_tag="KR231_002685"
     CDS             23443..24459
                     /locus_tag="KR231_002685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-hydroxy-acid oxidizing protein"
                     /protein_id="HBH0005049.1"
                     /translation="MEYNELLKSARENLNGSCKVCKVCNGVACAGEVPGMGGKGSGSS
                     FIENSKSLEKVKVNMRVIHDVSNPDTSIEMFGKKMSAPIFAAPVTGTTLNMGGKINER
                     DYIEPVVAGCANSGIYAMVGDTAVDAFLMENLDVVKKYNGAGIVFIKPWDNENIIKKI
                     RLAEEAGAFAVGVDIDACGLVTLSLHGKPVLPKNVKQIKELVKSTKLPFILKGIMTVE
                     DALMAVEAGVDAIVVSNHGGRVLDCTPGACEVLPKIADAVKGKVTILADGGVRTGLDV
                     LKMIGLGADAVLIGRPFVTASFGGATDGVETYVNKLQSELSSSMILTGCQTIKDIDGK
                     VIYK"
     gene            24525..24773
                     /locus_tag="KR231_002686"
     CDS             24525..24773
                     /locus_tag="KR231_002686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0005050.1"
                     /translation="MSRKAYEEALVELEKFIDERKEIIKSAEDCIDKYIVDRTLPFDY
                     KDKCVEWQQELLDIAEAQVLEANELSVLLQEKKELEED"
     gene            complement(24949..25446)
                     /locus_tag="KR231_002687"
     CDS             complement(24949..25446)
                     /locus_tag="KR231_002687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CarD family transcriptional regulator"
                     /protein_id="HBH0005051.1"
                     /translation="MYKIGESVMYPKEGACSVNDIVTKKINHEMQKYYELSVIFNSNL
                     KISIPVLNADRIGIRPVMDGNDVDNFIQSINKTDGVWIFDRKERLKLYQDKFHSGDVF
                     EIVKLIKMLMIQDSSKQLCSTDKEFLNKAQKFALSELAAAQCKSYTMVLEEMKKHILN
                     SKNTN"
     gene            complement(25690..>26388)
                     /locus_tag="KR231_002688"
     CDS             complement(25690..>26388)
                     /locus_tag="KR231_002688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBH0005052.1"
                     /translation="GGSLWAESQIESFITKSLKLKVDKNIDDKLTKTNIIDNKPDKNK
                     GSFLVVFLICYFMYINAAHLASDLFTLKKSNVLKRLISTDNKDIKIIFSIFLGLFFIQ
                     SIVYTFALLCFSIIEDFNLSLNVLMIVLANSFVSTGFVFWVARVFKNESSISLISTFY
                     SLIGLAISISSLIPSMDKLSFMTNLSKFTPFYWTIDAIKNNGSILINIIALILIGIIF
                     VTAGSLKLRDFAKN"
BASE COUNT        11078 a         2534 c         4782 g         7994 t
ORIGIN      
        1 agtagaaata tatctgacag agaaatgtta agtacagcaa aaaaatatat agaagatgag
       61 aagtatagaa tacaaaatag taagtatgag ttaattgaag ataagataga aaaaaattac
      121 ataaatggat atgaaattaa cagtagaata gagcaaattt tagattatta tcaatgctat
      181 gaaataaata tagagataaa aaatgaattt aaaaaactga ggtttaatag ctatgttact
      241 agaaaataaa ggctctatat taataataac attgataata ttttctatta taagtactgt
      301 gtgcattatg tgtataggtt taatttatac acataataat atgtttgagt taggatacaa
      361 agacattcaa ctaaaagaaa tttctttaag tggaatagaa atatcagtaa gtaatgtact
      421 ttcttgtgtt gaggaagcta ttgatatatc taataatgaa gacgaattta gagaatattt
      481 cttaggaaat aatatgattg aatgtataaa aaaaataaaa gatacatctt atagtagttt
      541 agaagaactt tctttaaaag tagaaaataa tactatttat gacagaggag atttttttga
      601 atttgatata gaaagtaatg ttagagaaaa agaattttta aaagcaataa aagtaagagt
      661 gaaaatcaaa aatccatgga taggaattga tattgaagat tatatggata aatctaataa
      721 caataaaatt gatgacaaaa cattcaataa ttataaagca tctgaaaata atgaaattat
      781 aaatcaattt aaaaatgaaa gtgaaaatat aaggaatcaa gaggttgttg aatttacaga
      841 agaagatgaa gaagaactta aacaaaacat aattgaaaat ataaagaaga attttgatga
      901 aaaaaaccta gtacaggtat ataagtatag gggtgtataa ctttgaaaaa agaaggaatg
      961 tgactgtaat agaattaata gtatctatca gtataatact cttgatagtt acattatctt
     1021 ttccaaaaga taatcttgaa aatcataaaa taaatttatt tgcacgtcaa ctttgttcag
     1081 atataaggta tgttaggcga attaatatgt ttagcaacta caatacatat atatattata
     1141 taaatcaagg taaacacgaa ggttatgtat tgagaaaaga tggtaaaaac attaaatcaa
     1201 taatgctacc taaaaatgca aaaatagcta ggagtattga aataataaag tttaaatctg
     1261 atgggtcgcc tcaaaaggcg tctacaatag aggtatataa taatagatta agaaaaacta
     1321 taacaataac acctgtaagt ggaagagtac ttctgaaaga gggaaaatat gaaacataaa
     1381 tatggttact tgcttttgga aagtgtcgta tcattgtctt caatggtgat aattatacta
     1441 gttttatatt ctatattttt gtctacaata aacttaaagt taaaagtaga agataagata
     1501 gaactacaac aacaaagtct tgaaatcata aaatctatgg aaggaattat tagcaattct
     1561 atgggaataa tgaatgtatc taattatgaa gaaacattta aaaagacaac atctataaaa
     1621 tgtagatatt tagatgaaaa taataatgaa gaaggcataa gtaataaaga aattatattg
     1681 aatgaaagac gaaataagtt atttgtaaat tctttaaatg gcgaaagtag tcaagcaggt
     1741 ggttatgaaa ttggagatta tgtagatgaa atgtatgtat caattactaa taatggtcaa
     1801 tacgttaata ttaaattgaa attatcaaaa tgtagtcaaa aatatgagac tgatttcaaa
     1861 ataaaagtat ggaattttag tgaaagtata taaaaataca taaatttaag agaaagaaat
     1921 gacatcaata agtcatataa aatataatta ttgagaacta tataactaaa taatatcaat
     1981 atgtaaagtg tatagattaa gaatatagag gataataata aaaatataga ataagtaatt
     2041 tgccaaatac ttgtttatat tgtataactt atgatattat gatattagta aaaatttgta
     2101 atcctgactt gacagaattc aagtaagaga tataatttta aaggcatagt aatgtaaaat
     2161 ttactaaaaa ataagaaatt tattttaata tggaggaaca aaaaatggta tcagcaggtg
     2221 attttagaaa aggtgttaca tttgaaaaag atggacaacc atgtttagta gttgattttc
     2281 aacacgttaa gccaggtaaa ggagctgctt tcgttagaac taaatacaaa aacttaaaaa
     2341 caggagctat aagagaagaa agtttcaatc caagtgaaaa attccctaaa gctgttatag
     2401 atacaagaca aatgcaatat ctatacaatg atggtgagtt atattatttt atggatcaag
     2461 aaaattttga acaaatacca ttaaactatg agcaagttga agatgcaatt aagttcttaa
     2521 aagaaaatga agttgctaca ataagatttt accaaggaca accattccaa gtggaagcgc
     2581 caaactttgc agagctagaa gttacagata cagagccagg cataaaaggt gatacagcaa
     2641 gtaatgtaac taaagcagct acagttgaaa ctggagcagt tgttcaagtt ccattattta
     2701 taaatactgg agataaagta aagatagata ctagaacagg tgaatattta tcaagagtat
     2761 aaaaatttat gtatataaaa gcttatatgt cttaataata taagatatat gagcttttag
     2821 tttatatata aaaaagaaag cgaggggtgt tacatgaaac atttatatga agaagttgca
     2881 tacttaaaag gcctagcaga aggactagaa ataagtgctg aaagtaaaga agggaaaatg
     2941 atacataaaa tagttgatgc attagaagta tttgcagatg ctattgtaac attggatgaa
     3001 gaacaagaag aacttcaaga ttttgttgaa tctatagatg aagatttagc agatttagaa
     3061 gaagatattg ctgacatgga agaagatctt tatgaagaag atgacgatga ggatgatgag
     3121 gacttcagct atatagaaat ggaatgccca aattgtggag agttagtaga aatagacgaa
     3181 gatttgttat atgatgatga agtagatgtt gtttgtcctg attgtaaggc tgtgatatta
     3241 tcatcagaag atgattgtga tgatgattgt acatgtggtg gttgttcaag ttgtgatgat
     3301 agagagtaaa aattcataag aattaaaact gcctatgatg cctatgagat attttgcttc
     3361 ataggtagtt ttatttttat gaggaagggt attatgtatt ttggttttgc aatacttgga
     3421 caaaaatagt acactagaat ttatagaata ggattttgga gggatgtaaa tatgaaaata
     3481 agtaaaaaat tactagataa tatacaaaga tttgaaaatg ttataaatta taaatttaaa
     3541 aataaagaat atatactaga agctcttact catagttcat attctaatga aaataaaaaa
     3601 tataatttta acgaaagatt ggaattttta ggggattcgg ttttaggcat agtgataagt
     3661 gattatttat ttaatgaaga agctaatctg cccgaagggg aactaactaa acttagagca
     3721 aatatagtct gtgaagattc attaagtgaa gtagctaatg atataaattt aggtattcac
     3781 atgttattag gtagaggaga agaagcaaca ggaggaagac ataggacttc aatattagca
     3841 gacgcatttg aagctgtaat agctgctata tatcttgatg gaggttttga aagtgcaaga
     3901 cagtttatac ttcatcatat ggaaaatata atttatgatt caagaaaagg aaatatattt
     3961 agagactaca aaacgcatct tcaagaggtg ttacaaggga atggagaaaa taatatctgg
     4021 tacaggctta tagaagaaaa aggaccagac cataataaaa gatttgtaat ggaagttgga
     4081 attaatgacg atgtacttgg tataggagaa ggcaagagta aaaaagaagc tgaacagtta
     4141 gctgctaaaa tagctttaaa gaaaaaatta tgggaaaaat aaatataata tgtaaaaata
     4201 taaaaagaaa tatttatatt agaaggatgt tgtagatgaa aaagagaatt atacctatat
     4261 ttgttcctca caaaggatgt cctcatgatt gcatattttg taatcaaaaa aaaataacag
     4321 gtgtgagtac tgatgttact agtgaagatg caagaaatat aattgaggaa tgtttagaga
     4381 ctatagataa agatgcagat gtagaaatag cattttttgg tggtagcttt actgctatag
     4441 atattgatat acaaaaaagt ttattatcag ttgctaaaga atatgtagaa aaaggtcttg
     4501 taaaagatat tagaatgtct acaagaccag attgtattga tgaagatata ttaagtatgt
     4561 taaaagaata taagacaagt ataattgaac taggagtaca atccttagat gaaaaagtat
     4621 tattagatag tataagaggt catcaatctg aaattgtata caagagttca aagatgataa
     4681 aaaatagtgg aatcaaactt ggattacaga tgatgattgg tcttccagct gacacagaag
     4741 aaaagtgtat atttacagca aaaaaatttg tagagctaaa accagattgt gttagagtct
     4801 atccaacttt ggtagtaaaa gatacaggtc ttgaaaagtt aatggaacaa aataaatata
     4861 atccatttac ccttgaagag agtgtaaata tagtaaaaaa agttcttgta ctgttttatg
     4921 ttaataatat caatgtaata agagttgggc ttcaagctac tgatgatata caaattggaa
     4981 aagctgtttt agcaggacca tatcatcctg catttagaga gttggtagaa gcagatatga
     5041 taaaagatta tttagaattt gttattttgc aaaataaaaa tataaagcaa atgttggtca
     5101 aatctaataa aaagaatatt tctaaaatca taggaaataa aaaaacaaat gttaaatata
     5161 tggaagaaaa atttggtgtg cttttaaaaa cacaagaatc agatttagat ataaatcaat
     5221 tagaaattgt gttagatggg aaaagtttaa ttagtgctaa tatgagagac attcatagaa
     5281 aattgtatga catttatgac ctttagtttt aataatgaag ggagagaaaa gatttgtatt
     5341 taaaaagact agagttaaag ggatttaaat cctttccagt aaaaacagat attattttta
     5401 aagaaggaat aacagccata gtaggaccaa atgggagtgg aaaaagtaat atatctgatg
     5461 ctgtaagatg ggtattagga gaacagagta ttaagagtct tagaggtgat aaactcgaag
     5521 atgtaatatt tgcaggtaca gatacaaaaa aacctatgaa ttattgtgaa gtggctctta
     5581 ctattgataa ttctgaaaat caattggaat tagattttac agaagtaact ataagaagaa
     5641 gggcttatag aaatggtgaa agtgaatttt ttctaaataa taaaagttgt agattaaaag
     5701 atataaaaga agtcttttta gatactggta ttggaaaaga tggttattca atcatagaac
     5761 aaggaaaagt agatgaaata ttaagtaata atcctttaag cagaagaaaa gtttttgatg
     5821 aagcttgtgg catatcaaaa tatagatata aaaaacagga agcagaaagg aatttaagta
     5881 atacaaagga aaatttagaa agaatagatg atgtatatat agaaattgaa aatcaattaa
     5941 agcctctttt taatcaacag acaaaggcaa aaaagtactt ggaaataagt gaaaaattaa
     6001 agacacttga agtaaatagc tttataagag aaattgaagg aatagaaaaa gaattaagtg
     6061 aggttaatga acatcgtaag gttattgaaa aggagctcaa tgaaaaagaa gaacaaaaaa
     6121 atgttgtaga gaaaaagcaa gaagatatta ataaagaggt agaggtatta caagatgtaa
     6181 ttgaaaaatc tgtagattat ataaattcaa ttaaaggagt tatatcaaaa aaagagtccc
     6241 aaataaattt aattaaggaa agaataagaa attttacgaa tgaaattagt agaaaaaatt
     6301 tagaaataaa tgatataaaa gagaagctaa atgaaaataa gcaatacata aaagaattag
     6361 aaagcaataa attatcaggt agtgaagaac tatctacctt gcaggaaaat ataaaagtat
     6421 tggaagcaag taaagataaa caaaaaatta agttagaatc cctaaataat gagatagaat
     6481 tattgaaaga aagtataatt gatatattaa ataaaaaaca agagtttagt aataagctgt
     6541 ccactttaaa cgcaaataaa gaaaatatga atatcagaga tgaaaatata aattcagaga
     6601 taacagagtt aaacaaaaat attgaaataa aatcatctga attagatact ataaataaag
     6661 aatttaatat gcaaaatgaa aatttaaaga atgtaaataa tagacataaa gaattatcaa
     6721 ctaatttgca ggattcaatt agtgaacaca ataaactaga agatgaaata cagaaaagta
     6781 aatataattt aaatggatat aattcaaagt taaatgtcta tatagatatg gaaaatcatt
     6841 atgaaggatt taatagagga gtaaaagaag tactaaaaaa taaaaattta aaaggagttc
     6901 atggagcatt aggacagatt ataaatgtac ctgaaaaata tgagaaatct atagaagcag
     6961 ctcttggtgc ttatatgcaa aatataataa ctgataatga gtttagtgct aagtctgcaa
     7021 taaactatct aaaacagaat aatttaggta gagtaacatt tcttccatta aatataatta
     7081 aatcaaataa aataagtcta ggaaatttaa aagcaaatac taagttcata ggaatagcaa
     7141 gtgatttaat tacatttgat gaaaagtata gaaatataat tgaaaatata cttggaagaa
     7201 caatacttat aaataatata gatgagggca taaaatttgc aaaagaaact ggtcataggt
     7261 ttaaaatagt aactttagat ggtgaaatct taaatccagg aggttctttg actgggggaa
     7321 gtctaaaaac taatgggaat atactatcca gaaaaagata cattaatgaa tatacagaaa
     7381 agataagtaa tatcaagaat gaaatttcac atctagaatt aaaaagagaa tctttagaca
     7441 aagatgtgaa aaatatcaaa aatgaaattg attcacatga aagtaaaata aaagatttag
     7501 aaaaaagtat aataataaaa agtacaagta taaagaatgt tgagtctgaa attgaatcgt
     7561 taaaaggtag tattactaaa ttagaaaatg agaagaatga tttaaattct aacctaaatt
     7621 atacacttga aaaaagtgat gatgttagaa aagatatgga agagttagat gatttataca
     7681 ataaaaataa agaaaaaatt gatgcattga atgaggaaat aaaaagatac aatgatttat
     7741 atgataaaga aaaatctgaa tttgatgaat tgaacttaag tttagtgaag aaaacagaag
     7801 tttacaatag tatagttaga gatataaaaa gaatatctgg tgaaaattgt gagctagaag
     7861 aaaaaaataa acaattagaa gagtcattaa attatgaaga acatgaaata attaaattac
     7921 aagattctat actcactgaa gaaaaagaaa aagaaaattt aacaaaacaa ctaggggata
     7981 gtaatagaaa tcttgaaact agaaaaatag caaaagatga tttaaaaaat agttttgatg
     8041 aaattaataa agaattaaaa actatagata gacagcatat agaacttaaa gaaagtttat
     8101 ttaaagttgg tggaagatta gaaagattaa aaactagtca agacacatat ataaataagt
     8161 tgtttgagca atatgatatg accttagtac aagcattgga aattaaagat gaagatttgg
     8221 atatagatag aaaattctta gaaagtctaa agagagaaat aagaagtctt ggaaatataa
     8281 atatagactc tataaaggaa tatgaggaaa taaaagaaag atacgatttt tatagcgaac
     8341 aaaagcaaga tttagaagag tctatggaag agatagaaaa acttatacat actttagaag
     8401 aaaatatgaa atctgaattt gaaattaagt ttgaagaaat aagtaaaaat tttaaatatg
     8461 tatataagag attatttggt ggaggttgtg gagaattaac tattttagat aaagaaaatt
     8521 tattagaaag tgatatacta ataacagctc aacccccagg taaaaaaatg aaaaatttaa
     8581 acctattatc tggtggagag aaagctttaa cggcaataag tatattattt gctatattga
     8641 ttacaaagcc aacaccattt tgtatattag atgagattga agcgccactt gatgacgcaa
     8701 atatatttag atttggagaa tttttgaagg atttatctaa agagactcaa tttatatcag
     8761 taactcatag gagaggaact atggaagctg ctgattatat ctacggagtt acaatgcaag
     8821 aaaaagccat ttcaaaagtt attagtttaa aattaaaaga agctcaggaa ataacagata
     8881 ttatataact tagattgaca taggaggaat aacagtgtta aaaaaattat ttggttttgg
     8941 aaaagacaag gaaaaggaaa tagaaaaaaa agatgctgaa gaagaaatag aagttgaaga
     9001 cagtgttgat aatttagaaa acttggaaga aactattttt tcaggacttg aagaagaagt
     9061 gatagataaa gtggaagatg ttgaagaaaa aaatgaggaa agtgtcaata atgaaggcac
     9121 tgaagaaatc gaaaactttg aaaaaataga agttgagatg gatagtaatg gaaaagaagt
     9181 agaaaatatt tcaaataatg attctcaaga agagataatc gaagaattag aaaattatga
     9241 tgaaattgag tctaaagaga tagaagataa agaagataag aaagttaact tgtttgaaag
     9301 actaaaacaa ggattgacaa aagcaaagca aggaataact gatagaatag atgaagtttt
     9361 aaaatcatat acaaagatag atgaagaatt acttgaagat ttagaggaaa ttttaataac
     9421 agcagatgtt ggtgtaaata caactatgga tataattgaa agactaagag ataaaataaa
     9481 gcaaaaaggt attactgaac caataaaggt aagagaagaa cttaaatcta tagttgaaga
     9541 tattcttaca aatgaaaact ctacactaga tatagaacca gtaccatgta taatattaat
     9601 ggtgggtgta aatggggtcg gtaagactac tacaataggt aaactagcaa atagatacaa
     9661 aaaagatggt aaaaaagttt tattagcagc agcagataca tttagagcag cagcaacaga
     9721 gcaattagaa atttgggcaa atagaaccaa tgtagacata ataaaacatc aagagggagc
     9781 agaccctgga gctgtagtat ttgatgctat aaaagctgca aaagctagaa aaacagatgt
     9841 attaatatgt gatacagcag gaagattaca caataaggct aatcttatga atgaacttgg
     9901 aaaagtattt aaaatagtag atagagaatt tccagaagca aaacgagaag tacttcttgt
     9961 ggtggatgct acaacaggtc aaaatgcagt tgttcaagca aagacattta aagaagttgc
    10021 agatataaca ggtatagtac ttacaaaact tgatggaact gcaaaaggtg gagtagtcct
    10081 tgcggtaaaa tcagaagtag atgtacctgt aaaacttatt ggagttggag aaagtgtaga
    10141 agacctacaa gatttcaatg caaaatcatt ttcagatgca ttatttggta actaatgttc
    10201 ttttaaaaat aatggttgac aagagtgttg ttatgatata aaatacaata gtgtaaagta
    10261 aataaccttt acagtatact gctaggaagt gtaagatatg aatatagaaa aaatggtcga
    10321 aattggattg ttatttgaac agtataaaga attattaact gacaagcaga aagaaatagt
    10381 tgctctatac tatgaagaag attattcttt aggtgaaatt agtgaaaatc tgaatgtatc
    10441 aagacaaggt gtttatgata ccttaaagcg ttcagaaaaa atactaagag attatgaaga
    10501 aaagttacac ttagtatcaa agattcaaga gcaggaaaaa aatattaaga ttataaaaga
    10561 taaaattatt gacattaaag aagatttatt gcacaataga gattgtgcta atttaatccc
    10621 taagctagaa aatatagaag atgtatgtag ggagatgata aaatgatatt tgaaggattg
    10681 tctgataaac tacaaggggc atttagtaag ttaaaatcta aaggaaaact tacagaagta
    10741 gatgtaaaaa atgctatgag agaagttaaa cttgctcttc ttgaggcaga tgttaacttt
    10801 aaagtagtta aagatttcat aaaaaaagtt caagagagat gtgttgggca agaagttatg
    10861 caaagcttaa ctccagctca gcatgtaatc aaaattgtaa atgaagagct tacaagttta
    10921 atgggagatg tacaaagtaa agtaatgatt tcctcaaagc ctcctacaat tttaatgatg
    10981 gttggattgc aaggtgcagg taagactact acagcaggaa aacttggagg atattttaaa
    11041 aagcaaggta aaaaacctct attagtagct tgtgatattt atagaccagc agctataaag
    11101 caacttcaag ttgttggaga aaaattggat atacctgtat tcaatatggg agataaagaa
    11161 aatccagtaa atattgcgaa agcaggttta agccatgcga ttaaaaatgc taatgattta
    11221 gttattatag atacagctgg tagacttcat atagatgaag tacttatgga tgagttaaag
    11281 tctattaaat cagaagttaa gccacatgag atacttttgg ttgtagattc tatgacaggt
    11341 caagatgctg taaatgttgc agaaagcttc aatgaggcac ttggtgttga tggagtagta
    11401 ttaactaaat tggatggaga tactagagga ggtgctgcac tttcaataag agcagttaca
    11461 caaaagccta taaaatttat ggggatggga gaaaagctag atgatataga acctttccac
    11521 ccagatagaa tggcatcaag aatattaggt atgggagatg tcttaagttt aatagaaaaa
    11581 gcacaagaaa atatagattt agagaaagct aaagaattag agcaaaaaat taaaaaacaa
    11641 gagcttgatt ttgaagattt cttacaacaa atggaacaaa tacaaaatat gggacctctt
    11701 gacaagatac ttggtatgat acctggtatg ggaaatgtaa aagaccaact tggagatgta
    11761 gatttgaatg gcaaagaaat gaagagaaca aaagccataa ttcagtcaat gactacatat
    11821 gagagaagaa acccaggagt attaaatgct tcaagaaaga aaagaatagc taaaggcagt
    11881 ggaactagtg tacaagatgt aaatagactt ataaaacaac ttaatgaaat gaaaaaaatg
    11941 atgaagatgt ttgctggttc acaaaagagt atgaagaaaa ggggcggctt aggcggttta
    12001 ccttttttta aataaaatat aaaaaagtaa aaattattcg gaggtgactg taatggcagt
    12061 taaaataaga ttaaaaagaa tgggagctaa caaaaaacct ttctacagaa tagtagtagc
    12121 tgattcaaga gctccaagag atggaaaatt tatagaagaa ataggatact ataatccaat
    12181 ttctgaacct aaacaagtaa gaataaatga tgaaaaagct ataaaatggt tagctactgg
    12241 tgctcagcca acagaagtag ttaaaaaatt acttgtaaaa aacggagtaa tagaaaaatt
    12301 cgaagcttct aaacaagcaa aataattttt tcttggcaat tagtttaagt aagggctcat
    12361 tgctaaggtt actttaggag atgaaatata tgaaagagct agttgtagat atagctaagg
    12421 ctctagttga taatcctgac tcagttgttg ttgaggaatt tgaagataat gatggtatcg
    12481 tcttaaagct tacagttgct caagaggata tgggtaaggt tattgggaag cagggaagaa
    12541 tagctaaagc tataagaact gtcgtaagat ctgttgcaaa tagagaaaat ataaaagttt
    12601 ctcttgagat agtataaaat aggaggatta ggtataatgc ctagtccttt ttatataaat
    12661 gcgtagttta agattttatg atgatatgac cacataagat taaatttttt aagaaggtga
    12721 taacatgaaa gaaaaattaa ctcattttaa ggtaggtcaa atagtaaata cacaaggttt
    12781 aaaaggtgaa gtaagagttt atccgcttac tgatgatata gagaggtttg atgaattaaa
    12841 agatttctat ctgggaaaag atttaaataa taaattggct gttgaaaaag taagatacaa
    12901 aggttctatg gttataatga agataaaagg catagacagc atagagaaag cagaaaaact
    12961 aaaaaataaa tttatgtatg tatctagaga agatagcaga gagcttgaag aaggcgaatt
    13021 ttttatagca gatatgattg gaatggaagt tttaactgta gatggaaaat atgtaggaat
    13081 actagaagat gttcttcaat actcagcaaa tgatgtctat gtagtaaaag gtgaggaaga
    13141 taaagaattt atgataccag ctataaaaaa atttgtacct acaatagata ttgatgaaag
    13201 aaaaatgatt atagacccta ttaagggaat gatagattag gtggtaatat gagatttcat
    13261 ataatgacac tttttccaga aatatttaat tcgtacatgg atgaaagtat aatgaagaga
    13321 gcagttgaaa aaggtataat tgaggttcat atatataata taagggattt ttctaataat
    13381 aaacataaaa aagtagatga ttatccattt ggaggaggag cggggatggt aatgactcct
    13441 caacctatat atgacacata taagcatata ataacaactc ataatataaa taacccaagt
    13501 gtaatttatc ttactccaaa aggtaaggta tacaatcaat ctatggcaaa gcagatgtct
    13561 ttaaaagaag atataatact actatgtggt cattatgaag gaatagatga gagaatcatt
    13621 gatttaatag ttactgatga aatttcaatt ggagattatg tattaactgg gggagagctc
    13681 ccagcactta taatgataga ttctatatcg agattaatac caggtgtatt aaaccaagaa
    13741 gaatcatttg aagaagaatc atttaaagac aacttattgg aatatcctca ttacactaga
    13801 cctagagatt ttgaaggatt aaaagtacca gaagtgcttt tatcagggaa tcataagaag
    13861 atagatgagt ggagaagaga agaatctata aggataacca aagaaagacg atttgattta
    13921 tataaaaagt ctaatgaaaa ataaaaatat aatgaaaaat taatatatat gtatacaata
    13981 aagtacctat aaatggaatt aaaaacataa aagtgcttgt aataactatt gaagtatagt
    14041 ataatataaa atgttgaaaa tacgggcgtt cctctgttta cactggtcgg gtagttaaga
    14101 acgtctatga tatctaggag gaagaaagat gaatgaaatg ctaagagcaa ttgagcaaga
    14161 acaattaaaa aatgaagttc ctaattttgg acctggggac acagttaaag tacacgttag
    14221 aattatagaa ggaaaaagag aaagaataca agtattcgaa ggtgtagtat taaagagaca
    14281 aggtggagga gcaagagaaa ctttcacagt tagaaaaatg tctttcaatg ttggtgtaga
    14341 aagaactttc ccagttcact ctccaaaaat agaaaaaata gaagttacta gaaaaggtaa
    14401 agtaagaaga gctaaactaa actacttaag aggtagagta ggtaaagctg ctaagataaa
    14461 agaagctaga aataaataat taaaaacttt acttataaat ggggggctga tttatcagtc
    14521 ctctttctat tttaatgaaa attacaacaa ataattatac tagaaataaa tagaaatatt
    14581 tgttgaaaat atagattatt tatctatgaa tttatagctt ttaaaatgaa aaataaaatt
    14641 ggtaaatatt gcattatatt ttgtaacgat attaaaaata agagaacagt attatgtaaa
    14701 gtatgacgtt aaaaagatga caatattata gtttgtgaag atatattttt taagtggaat
    14761 taggatataa taatataata ttaataagga gtgatacatg tgtcaaatga atacgaagag
    14821 tatcttatgg atgacaatct acatataaac tggtatccag gtcatatgaa aaaaactaag
    14881 gagttagtaa aaaataactt aaaattgatt gatgtagtaa ttgaactttt ggatgctaga
    14941 atcccgttta gtagtaaaaa tccagacata gacaggcttg taggagataa gccaagagtt
    15001 gtcgtactta ataagagtga tatggcagat agggataaat tgaatcaatg gattgaatac
    15061 tataagaaaa ttaatatcaa agctatacca gtagatacaa taaaaggtgt tggtataaat
    15121 aagataatcg aagaatgtaa aaatgtaact agagaaaaaa tgagttcttt aaaagacaaa
    15181 gggagaaaag aaagagctat acgaataatg atagttggcg ttccaaatgt tggtaaatcg
    15241 tctcttataa acaaattaac aggtagaaaa agcactcaaa ctggagataa gccaggagta
    15301 acgaaaggga aacaatgggt tagattaaag ggaaatcttg aacttttaga tacgcctgga
    15361 atactttggc ctaagtttga agaccaagaa gttgcattaa atttagcatt tagtagagct
    15421 ataaaggatg agattttaga tactgaaact ttggctttaa gacttataga aaaacttatg
    15481 aaaatagaac ctgagaagtt gaaagccaga tataagttag attgtctagg agaaactcca
    15541 attgaaacta tggatatgat tggtcataaa agaggattta taacaggtaa aaaagaacta
    15601 gattatacac gcatagccac aactgtatta aatgaattta gagatggaaa aataggaaat
    15661 ataacattgg aagttccaga aaacgttaaa agatagattt taaaacaaaa tcaaaaattt
    15721 aatgttaaaa atttaaaaaa gccttttagc aaaggctttt ttattttttt gaaatataga
    15781 caaatatctc catataaaag tataaattag gttagaaagc ctttaaaaat attaatttaa
    15841 gacaaatata cctaatattt tgaaaattaa aatgagtgtg attattaaaa attttagcat
    15901 attgacttgc ttgtttcgta taatatataa taagcacaaa taaatacaat atattaaaaa
    15961 tttaatttat ttaattttat taatttaata ataagttctt attgtttaat tcaacttact
    16021 tatgcaagcg taaacaatcg agacatttta ttaatttaat aaggttaaaa agggggattt
    16081 tataatgggt aagaccaagg atgttatagt atttggattt gcgttatttg caatgttctt
    16141 tggagcaggt aacttaatat ttccacctta cttgggaata attacaggtc cagaatggtt
    16201 aattgccttc ttaggattta cgtttgctga tgctggattg gcacttctag cagtaatggc
    16261 tacagctaaa ttcgatggaa acgtagttga aatgtttaaa agatgtggta tgaagttagg
    16321 gattcttata ggttgtgcag atattttatg tataggacca ttcttagcta taccaagaac
    16381 aggtgcaaca acttatgaaa tgggtataat gcctttattt ggaacttcaa ttccagtgtt
    16441 attattctgt atactttttt ttgcgctttc atatgtacta acaataagac cttctaaggt
    16501 cgtagatata gttggacagt ttttaactcc agctctttta atagctttag catttataat
    16561 tataaaaggt attatatcac ctcttggaga tatagtagat aaacctatga tacctaatgt
    16621 atttgcagaa ggtataggtc aaggatatca gacaatggat gcttttgcag caatagcact
    16681 tgcatcagtt ctaatagtat ctttaaatga taaaggatat tctactatta gtgacaagtt
    16741 aaaaatgatt ggtaaggcgg gtgttcttgc ttgtggagga ttagctctag tttatggagg
    16801 attatgtttc cttggagcaa ctgtatcaac aatgtatgga acagatgcag tacaatcaca
    16861 agtaatagta aatataactg aaggattgct tggaaatgtt gggaaagcga ttttagcagt
    16921 agtagtatca ttagcatgtt taactacatc tataggtctt acatctgcca caggtcaata
    16981 tttctctaga cttacaaaag gtaagttgag ttatgaaaaa atagtattag ctgtatctgt
    17041 attcagtgca gtagtagcat cttttggtgt tggaactata ataaagatag catctcctat
    17101 attaagtata gtttatccac catcaattgt tttaataatt ttagctttct tcaatgaaaa
    17161 aattaagaat gataatgtgt acaaaggagc agtatatatg tcattgcttg taagtatact
    17221 aacagttata tctagttatg gagtagctgt tccagtagta aactctttac ctcttaattc
    17281 attaggattt aactgggtgg tgcctgttat aatagctgga ataattggca attttatacc
    17341 atcaaagagt caatctaata cacttggaac aaactaagtt ttatttaatt aaaatataat
    17401 caattgtaaa taaatgagtt aactaaaagt aaaaggagtt atttgtacaa ataactcctt
    17461 ttatttttag attctatact taattatttg tatttaatat ggaaaaagta taagaaaata
    17521 tcaaaaaaat atatagttta ttttttaacg ataatagaga ttaaaaaaga attttagagt
    17581 aattttataa atttaagtat acatattaaa tgatttttac aaaaatataa tataaataaa
    17641 attgtgacaa taataaaata ataaaacaaa atttaagaca tatgattata taaatgtatt
    17701 aagtaaatgg gtaaattgtt ttcattgaga gatatattaa gaatttttag ttaattatga
    17761 cagataagta tgtaaacgtg aatactagca actgcaaagt ttaagtaagt tggaagttag
    17821 aaagtaattg atatgaagaa aaataagttg ataaatcata ataaggaatt ttcagaaaaa
    17881 atgattttaa gactaaaaaa caagaggcaa atctacataa atagaataaa aaacgaataa
    17941 agttaactgt caatttagca aaataaatac aaaatactac aagaattaac gtaaataggt
    18001 gctatgacaa aaggaaaacg attttttaag aatcataatt ttgaaaatta aaaaaattaa
    18061 aaatgctatt gactgctttt ttttcagatt atataataaa cacaaaatat ttaaaattta
    18121 aattgaatta aaaagattat atgaatgtaa aaaaggagag tgatatatac agtatataaa
    18181 gcaatacact taataacaaa tcgaataatc taaaaaatct taatatttta attattcaga
    18241 ataattaatt ttatcaagaa aaattagaga aaaaacaaaa aaccaactgt gtttaaagta
    18301 tacaggttga ttttgtttaa ttaagaaagt tgtattaaat attgtgaaga ttttataaat
    18361 tatgaaacat aattgacaaa tttaagtcaa aaatgtataa ttaaataaaa tctcgtcaaa
    18421 aggttttcat ttaatgaaga gattggactt attttttagt aaaaggtagt aaaattcaaa
    18481 tgggggtgct ttaaatgggt gagaaacaaa tcaattttaa agatgtaatt gtaattggat
    18541 ttgcactatt tgcaatgttt tttggtgcag ggaacttaat cttccctcca tatctaggag
    18601 ttttatctgg aagtagttgg ctaatagctt tcataggatt cctttttgca gatggtggtt
    18661 tggcattatt agcagttata gcagcaacta agttcaatgg agacacatcg aagatgttct
    18721 caagagcagg caaaggatta agtattgcat taggatgtgc aatggtaatc tgtatagggc
    18781 cacttttagc aatacctaga acagcagcaa caacttatga aatgggtata ttacctacaa
    18841 taggttctgg aataagccca gtaatattct ctatagtatt ctttgctcta gtattggttt
    18901 taacaataag accatcaaaa gttgtagata tagttgggtc aatattaact ccagctttac
    18961 ttatagcttt agcagtatta atagttaaag gtatcatatc tccattagga gaaataagag
    19021 acagttcttt aatacaaaat gtatttgcag aaggtataac tcaaggttat caaacaatgg
    19081 atgcattggc agctagtgta tttgcatcaa ttataatcat gtcagtaata gctaaaggtt
    19141 atacaggtga gaaagaaaag atgaaagcca caataagtgc aggtgtaatt gcagtaatag
    19201 gaatggcatt agtttatggt ggattatgtt atcttggagc aactgtgtct caacaatatg
    19261 gacaagatgt tcaacaaaca gctttaatag ttgcaataac agcagcttta cttggaacta
    19321 caggtaaaat tttattggct attatagttg cattagcatg tttaacaaca gctataggtc
    19381 tttcttcagc agctggtcaa tatttctcaa cacttacaga tggaaaatta aagtatgagc
    19441 atatagttat agtagtttgt gtatttagtg caatcatatc aaactttgga gtaagtacaa
    19501 taatacaatt ctcttctcct atactaagta tggtatatcc agcaactata actctagtta
    19561 tactagcatt atttagtaat aaaattaaaa atgacaacgt gttcaaatgt gctgcataca
    19621 tggcattatt agtaagtgta ttaacagttg caacaagttt tggtgtaaaa attcctctag
    19681 ttaatagctt accatttgct tcattaggat ttaactggat agttccagtt gtaatagcag
    19741 gaataatagg aaactttatt ccatctaaaa gcagtaaaac tgcataataa taaaaactaa
    19801 ttgataatta tggaattgcc tttaaattat ataggcaatt cctttttata tttaaaagaa
    19861 ttattaaatt attgtagata aaagaacatt attaatccta tttgataaat ttaaaaattt
    19921 atttttggag tagtatgatt tataaagata ataaaataaa aaagattcat ttataattat
    19981 aaataaaatt aaattatata ttataaatgt ttagtattaa tataaaaaca tcaatacata
    20041 tttttgtaaa gaaaaaataa agaatttatt ttctaaatac ttattaatta atcaaagtta
    20101 aaatgaaaaa aatataaaaa aataaagtat ataagagtat aatttgactt ttatatactt
    20161 ttttatatta tttttgagtt ttttaggaag atattttaca agttaagaaa actataagga
    20221 gtgttatatt gaatataaaa tagtataata tatattatgt tagataatta atatgaaaat
    20281 atacaaatat ataaaaagtt tgtttagagt tatagttaat gtgtgtatta atttaatact
    20341 aatttattgg aggtttaaaa atgaaataca taataaaaag agatggtaca aaagaacttt
    20401 ttagtaaaag taagattgaa gatgctgtct ataaagctag tataaatagt gaaggtggag
    20461 tagatagaga gttggcatat gatatatcaa gaaaaatagc taatgactat aattctatgg
    20521 aaaaatgctt atccgtagaa gaaatacaag atatagttga agtactactt atggaatcaa
    20581 atagaaaaga tatagcaaaa cactacatat tatatagaga aagacgctct gaaataagga
    20641 ctaaagcttg ggagtttgat gaattacaaa aatcaatatg gaagaacaag tatagacata
    20701 atggtgagag ttttgatgaa tggataaaga gaatttcaaa taatagttca agaatatcaa
    20761 aactaataag acaaaaaaga tttctatttg ctggaagaat tttagcaaat agaggattac
    20821 agaaagaagg aaaaaaagta acatattcta attgttatgt aatagaacca ccaaaagata
    20881 gcatagaaga tatatttgat actgcaaaaa aacttgctag aacttttagt tatggtggag
    20941 gagttggaat tgatatttca aagctaagac caaaaggagc gaaagttaac aatgctgcaa
    21001 aacatacgac tggagcagtc tcttttatgg aactttacag tatgacaact ggcttaattg
    21061 gtcaaagagg gagaagagga gctcttatga tttctatgga tgtaaatcat ccagagatag
    21121 aagactttat agatataaaa acagatttgg agaaggttac taaagcaaat atttctgtaa
    21181 gagtaacaga tgaatttatg caagctgtaa gagaaaaaaa gttatataat tgtacttttg
    21241 aagttgaaac tactggagaa aaaatagtta agatagtaaa tgcttatgat ttatttaata
    21301 aatttgtgaa aaataactgg gattatgcag aaccaggtat attgttttgg gataaaataa
    21361 aaacatataa ttttatgagt gaagataaga acttttgctt ttcaggagta aatccttgtg
    21421 cagaagaacc acttccaagt ggaggaagtt gtctacttgg ctcaataaac ttgtcagagt
    21481 ttataataca accatttggt gaacatgcta cttttgatat taataaatta aaatcttgcg
    21541 ttagagaagc tgtagtagct ttaaatgatg tcttagatga gggattgaac ttgcatccat
    21601 tacaagaaca aagagatagt gtacataagt atagacagat aggtttaggt gtaatgggta
    21661 tagctgatat gcttataaaa atgggaataa gatatggttc tgatgaatct ttagaactat
    21721 gtgatttaat tggtaagact atgttaaatg aagctgtgaa gcaatcagca ctaattgcta
    21781 aagaatatgg aacatttagt gagtataaat atgaaaatat ttctaaatct aagtttttta
    21841 tagaaaatct aaatgaagac actaaggaaa tggttaaaaa gtatgggctt agaaattcac
    21901 aacttttaac catacctcct acaggttcta tatctacaat gataggtatt agtggtggaa
    21961 tagaacctat atttaatctt tcatatataa gaaaaactga aagcttgcat gatgaggatg
    22021 tgtattataa agtatatact ccaattgtta aagagtatat ggacaagaaa ggtattacag
    22081 atgaagaatg tttaccagat ttttttgtta ctgctatgaa tataggatat gaagaaagaa
    22141 taaacatgca aaaagtatgg caaaagtata ttgatgcttc tatatcatct acaataaata
    22201 taccttttga aactacagtt gaagatgttt tcaatatata tattaaggca tgggaggctg
    22261 gtcttaaagg agtaacaata tttagagatg gatgtaaaag gagtggaatt ttaataaatg
    22321 aaaaaaagga agaaaataat aaagaagata aaaaagaaaa tagtaaaaaa gaatattata
    22381 aaaataataa aaaagaaaaa gataataaag atgaaaaagc caaagaaata ataaataaaa
    22441 attttgaaga agatgaaaaa tttgtgtgtc ctgagtgtgg aagtgaagga attgcacata
    22501 caggtggatg tagtatatgt ttaaaatgtg gctatagtgg atgcaattaa actctaatta
    22561 aaaaatttta atatatttaa aaattaaatt tttaaaaacg aaagatgagg gaatggtatg
    22621 caggataaaa gtgtgaggga gattaaagaa ataatagaga ctttagaagt agaaaaatat
    22681 atggaatata tagagctgtt aagagttgat gaaagaaaat ctgtacaagg tctagctata
    22741 aaactagcaa aaaagctgga taatattaga aaagaagaag aaagattgga aactataaat
    22801 atatttgaga acgaaggcta tgataaaggt tatttatata ttggaggaat tgatgaggcg
    22861 ggaagaggac cacttgctgg acctgttgta gcttctgttg tagtatttaa aaaagatacc
    22921 aaaatagaag gtgtaaatga ctctaagaaa ctgagtgagg caaaaagaga tgaacttttt
    22981 gaagtaataa aagaagaagc actagattat ggaataggta tagtaaacaa tgaagaaata
    23041 gatgaattta atatattaaa tgctacatat atggcaatga aaaaggctat aaattgttta
    23101 aaaaaagcac cggattattt attagttgat gcagcaacaa taccaggtat tgacatatct
    23161 caaaatccaa ttgtgaaagg agattcaaaa tctatatcaa tagcagcagc aagtatactt
    23221 gctaaagtta ctagggatag tataatgtac caatatgata gagtataccc agaatatggg
    23281 tttaaatctc acaaaggata tggaactaaa gaacactatg aagctattga aaaatatggc
    23341 ataactccta tccacagaaa aagttttttg aaaaatatac tgtaaatata atatgatata
    23401 atgtatataa tataaattac tatagttaat gggggattaa agatggaata taatgaatta
    23461 ttaaaaagtg ctagagaaaa tttaaatgga agttgtaaag tttgtaaggt ttgtaatggg
    23521 gttgcttgtg caggtgaagt gcctggcatg ggaggtaaag gaagtggttc ttcttttata
    23581 gaaaatagca agagtttaga aaaagtaaaa gtaaatatga gagtaataca tgatgtatca
    23641 aatcctgata catctataga gatgtttgga aagaaaatga gtgcacctat atttgcagct
    23701 ccagtaacag gaactacttt aaatatgggt ggaaaaatta atgaaagaga ttacatagaa
    23761 ccagtagttg caggatgtgc taatagtggt atttatgcaa tggttggtga tacggcagta
    23821 gatgcttttt taatggaaaa tttagatgta gtcaaaaagt ataatggagc tggaattgta
    23881 tttattaaac cttgggataa tgaaaatatt ataaaaaaga taagattagc tgaagaagct
    23941 ggtgcatttg cagttggagt tgatatagat gcctgtggtc tagtaacttt atcattacat
    24001 ggaaaaccag tacttcctaa aaatgttaaa caaataaagg agttagtaaa gtctactaaa
    24061 ctaccattta tattgaaagg tataatgact gttgaagatg ctttaatggc agtagaagca
    24121 ggtgtggatg caatagttgt atcaaatcat ggaggaagag tgcttgactg tacaccagga
    24181 gcatgtgaag ttttaccaaa aattgctgat gctgttaaag gtaaagttac aatacttgca
    24241 gatggtggag tgagaactgg tttagacgta ctaaaaatga taggtttagg tgcagatgca
    24301 gtattaatag gaagaccttt tgtgactgct tcttttggtg gtgcaactga tggtgtagaa
    24361 acttatgtaa ataaacttca atcagagcta agtagttcta tgatattaac tggatgtcaa
    24421 actataaaag atattgatgg aaaagttata tacaaataaa attttataca aaaaagagga
    24481 aaaatcattt taatgtagaa taattgtaca aagggggaat ttatatgagt agaaaagctt
    24541 atgaagaagc cttagtagaa ttagaaaaat ttattgatga aagaaaagaa ataattaaaa
    24601 gtgcggagga ctgtattgat aagtacatag ttgacagaac gctacctttt gattacaaag
    24661 ataaatgtgt ggaatggcaa caagagttac ttgatattgc agaggcacaa gttttagaag
    24721 caaatgaatt aagtgtatta ttacaagaga aaaaagaact tgaagaagat taaattttat
    24781 tagctaagag taaatcagta atatgattta ctcttagttt tttttatttg aataaaatac
    24841 atctatctaa ttgagataac tttattaata ttagattagg cagtttaaaa taagctaaag
    24901 tagcatggat gattagtata aaaaataaaa ccagtttaaa aaactggttt aatttgtatt
    24961 ctttgaattt aatatatgtt ttttcatttc ctctaatacc attgtatagg atttacattg
    25021 agcagcagct aattctgata aagcaaattt ttgagcttta tttaaaaact ccttatctgt
    25081 gctacacaat tgttttgaac tgtcttgtat cataagcatt ttgattaatt ttacaatttc
    25141 aaaaacatct cctgaatgaa atttatcttg gtacagttta agtctttctt ttctatcaaa
    25201 aatccataca ccatctgttt tattaataga ttggataaaa ttatcaacat catttccatc
    25261 cataactgga cgtatgccaa ttctatctgc atttagaact ggaatcgaaa ttttaaggtt
    25321 actattaaaa atgacactta attcatagta tttttgcatc tcatgattta ttttctttgt
    25381 tacaatatca tttacagagc aggctccctc ttttggatac attacacttt caccaatttt
    25441 atacatatgc tagttatacc tccaaattga attttagata ttgcaactta ggtacaatgc
    25501 tttaattatc taatgattaa tattataaca taaataactt gacaagtcaa aaatattaat
    25561 atataatata aggtttagac ttggtgatgt gtgaaactaa agagaaaaat ataagataaa
    25621 ataatttaat atgttgaaat attcttttac aactatataa aaatagatac taattatatt
    25681 taataattat tagtttttag caaaatctct tagtttaaga cttcctgcag ttacaaatat
    25741 aattccaatt aatattagag ctattatatt tattaaaata ctaccattgt ttttaatagc
    25801 atctatagtc caataaaatg gtgtgaactt tgaaagatta gtcataaagg ataatttatc
    25861 cattgatggt attagactag agatagatat agctagacct attaaagaat aaaatgtaga
    25921 tataagactt atagaacttt catttttaaa tactctagct acccaaaata caaatccagt
    25981 ggaaacaaaa ctatttgcta gtacaatcat caatacattc agactcaaat taaagtcttc
    26041 tataattgaa aaacataata gagcaaaagt gtatacaatt gattgaataa aaaatagtcc
    26101 taaaaatata ctgaaaatta tttttatatc tttattatct gtagagataa gtctttttag
    26161 cacatttgat ttttttaatg taaataaatc agaagcaaga tgtgctgcat taatatacat
    26221 aaaatagcat atcaagaaga ctactaaaaa tgaaccttta ttcttatctg gtttgttatc
    26281 aattatattt gtctttgtca atttatcatc tatattttta tccactttca attttaacga
    26341 tttagtaata aaagattcta tttgtgattc tgcccaaaga ctaccacc
//
LOCUS       DAEPHU010000063        25514 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 01A10CD0081
            SAMN05941466-rid12468953.denovo.063, whole genome shotgun sequence.
ACCESSION   DAEPHU010000063 DAEPHU010000000
VERSION     DAEPHU010000063.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941466
            Sequence Read Archive: SRR6291087
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 25514)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25514)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068158.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 22:43:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,892
            CDSs (total)                      :: 3,805
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 87
            rRNAs                             :: 8, 1, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 55
            CDSs (without protein)            :: 55
            Pseudo Genes (ambiguous residues) :: 0 of 55
            Pseudo Genes (frameshifted)       :: 21 of 55
            Pseudo Genes (incomplete)         :: 28 of 55
            Pseudo Genes (internal stop)      :: 16 of 55
            Pseudo Genes (multiple problems)  :: 8 of 55
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25514
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941466-rid12468953.denovo.063"
                     /strain="01A10CD0081"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            95..712
                     /locus_tag="KR231_002689"
     CDS             95..712
                     /locus_tag="KR231_002689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YmfQ family protein"
                     /protein_id="HBH0005053.1"
                     /translation="MDKEINLINYLPQILQDKEEYIKVFNVGNKEIKILHDKLKDLSN
                     DQFLEDLTISGIKRWEKIMSITPKSNESLEDRRFRIFSKYISKLPYSERFLRNWLDSI
                     VGEGNYELTINNATYNIHLESDARNQDWFEEVHSFVSNIKPCNMTLDYTRVLISKDNY
                     MNFGITTLMGQEITIYPWSPPDIETYGEIDVLTGNGVGYQEITIF"
     gene            724..1833
                     /locus_tag="KR231_002690"
     CDS             724..1833
                     /locus_tag="KR231_002690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728465.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HBH0005054.1"
                     /translation="MAIDKSYYTIITDVGKAKIANASVTGNKVGFVKIQLGDGGGSEY
                     TPTESQTALKNVVWEGNIGNTTTDETAPNCIILESLIPSSVGGFMIREIGYLDDENNL
                     IAISKYKECYKPSIEQGAVVDMKVKTVLIVSNVNNIELKIDPTIIFATLKDIQDLETK
                     IGTVNTKIDTTKTELTNNLETAKTELNTRIDTENEKQNIKIDQLIAGGSNVASTQTIT
                     IDDWVEDAENGFKATVTHSLLTQRIVVNIIDATTKENAVTNFKIIDDNSIEVRSETRS
                     ELNVYVINGNAETHFINATVDDNRVSEMTTYSSKKIEDSISSIQLIDTSISITDANDR
                     FTSDKLDGVLEEIMVEISGQRTKGITIVNNLIDMI"
     gene            1847..2485
                     /locus_tag="KR231_002691"
     CDS             1847..2485
                     /locus_tag="KR231_002691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0005055.1"
                     /translation="MTEKLTENASLGELMAALENVQTDFQTGKNNISSALGSPFIGTD
                     KFGTTKTKIETLKNVLVETINSKNVSATSSETFTNLIEKVNWIFQSIEIFSLKNRIQA
                     TTLNTPSIVYNEVSSIKGTLRFTGELKASKMRADYATAKIEILCGNRKEYFYVTDDTP
                     SASSSFVRFTKDIIVENGMDIKVQILLTSVGAGNLDGSYAARAEIEKLTILR"
     gene            2495..2707
                     /locus_tag="KR231_002692"
     CDS             2495..2707
                     /locus_tag="KR231_002692"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0005056.1"
                     /translation="MKKQVYYNSLDEKEKIISENSNLYVIEIYETLNENYLVLSSSPI
                     QDEKLSYEELENELLIMTNELQGGLL"
     gene            2707..2889
                     /locus_tag="KR231_002693"
     CDS             2707..2889
                     /locus_tag="KR231_002693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0005057.1"
                     /translation="MNINNVVVRILAERILNGGLNPLKNREFQLDDVTNTEYRKAVED
                     YIIKNSGVVEGIEPTA"
     gene            2923..4158
                     /locus_tag="KR231_002694"
     CDS             2923..4158
                     /locus_tag="KR231_002694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0005058.1"
                     /translation="MTFKELVNKVRNLVLEAKNVTIEDTENNFTSDNVEGALKEVFQN
                     GVNAKNNVVTALNSKGAEVTTSDTWEEIKNKIDIKEGRLDLRETILANSYSSYLVTNG
                     AIKYIEKYSGSLKALEYEEPYFYAIKGTHLIKINAIDESVIFDITLANANFSCICVTQ
                     EYLFISDNTKLYKINKLTGNEAQSIEGSYYKLCTYGEFIYGIYGDETSSILHKIRISD
                     MYIMLTKDMSSDRIYDFERGKFVCNNNGIYATTEHSNSSGLTECYLTKINFDFSVAKS
                     FRIGGYLYEKNIKFLNDFVFVSDSSRSIEVESGKKSGLAKYDANLNLITYGGSDRYEN
                     FEIYNGYIYTFNSLSSSPFIKINLNTLKEVNSYRTLINTNPQKGMFIINNIIFFIGGG
                     IHRNILSKKVYSDEKGEEL"
     gene            4155..4454
                     /locus_tag="KR231_002695"
     CDS             4155..4454
                     /locus_tag="KR231_002695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0005059.1"
                     /translation="MIYLGNLLDTEEQNIKYVGMIHYEPNLLSEENLKQGILVEELPT
                     PKYTENKETKLFINIDTKEVFYRYTDIKSSIEDKVNSTEQTIADLTFQLMSNGVI"
     gene            4456..4593
                     /locus_tag="KR231_002696"
     CDS             4456..4593
                     /locus_tag="KR231_002696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XkdX family protein"
                     /protein_id="HBH0005060.1"
                     /translation="MNWYKIITDFYNNGNWTKEQVKTAVTKNKITASEYKEIVREDYI
                     A"
     gene            4655..5086
                     /locus_tag="KR231_002697"
     CDS             4655..5086
                     /locus_tag="KR231_002697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin family protein"
                     /protein_id="HBH0005061.1"
                     /translation="MNVTIVFLATNIFIKLVILAIAFDTLLGCLRAIKTHQFNSSFGI
                     NGGIRKVAMIACIFFLAVVDILTKFNFLFMLPQDWVDFLRLNHLGISEFFSILFILYE
                     SVSILKNMYLCGLPVPKRLKEKIGSLLDTMTDELNVKGGSK"
     gene            5086..5898
                     /locus_tag="KR231_002698"
     CDS             5086..5898
                     /locus_tag="KR231_002698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HBH0005062.1"
                     /translation="MKICITVGHSILKSGACTSADGVVNEYQYNKSLAPVLADTFRKE
                     GHKVDVIICPEKQFKTKSEEKSYKIPRVNAGGYDLLIELHLNASDGQGKGSEVLYYSN
                     KGLEYATRICKKLGTIFKNRGAKLDKGLYILNSSKPTAILIESFFCDNKDDYEKAKKF
                     GYEGMAKLIVEGVLNKNIGNDGVKLMYKHTIVYDGEVDKIPATVVGWGYNDGKILICD
                     IKDYIPGQTENLYIVGGGACNKIGSITKEKYTMIKGNDRFDTLYKALDFIDR"
     gene            6148..6639
                     /locus_tag="KR231_002699"
     CDS             6148..6639
                     /locus_tag="KR231_002699"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0005063.1"
                     /translation="MAYENGTDFIDYFPDCIEKYKEDNKIFEKAILLLNLYMQKPTWP
                     HCVNEYKSQAEKILGEDPEFIGKYGIQLRKFYDEDENAKVSKEFKNDLYNFSKSTYDI
                     LDNVYFSKSHPFNLSSIYSTSRDDDFIIKIFRYDNNFLELEMSKREVESLINYLSDLL
                     KEE"
     gene            6676..7206
                     /locus_tag="KR231_002700"
     CDS             6676..7206
                     /locus_tag="KR231_002700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016056345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0005064.1"
                     /translation="MSFNEKKIEKHKCKNYHNDSSKDKYKYSQSEFIAATLKEADDMN
                     EEERRILEAEKRILETEKRVHQDNKEVKESIDKQFNDIKGIFKEYKNDLDKDRIELKN
                     DLARERAELKSDLKEAINEHKKVTEKDVSEIKNSMKGIEDRIDSTNKWIIGLCITTII
                     GIATMAITIGISIWPK"
     gene            complement(7616..7804)
                     /locus_tag="KR231_002701"
     CDS             complement(7616..7804)
                     /locus_tag="KR231_002701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0005065.1"
                     /translation="MTKTILCDYCNKGINKDDNKYITFHKKSHMKTNICINCALNLID
                     KDKLNENIINNQHDYSKK"
     gene            8062..8205
                     /locus_tag="KR231_002702"
     CDS             8062..8205
                     /locus_tag="KR231_002702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0005066.1"
                     /translation="MSEFLLGVLASLTASFITYIISRKVKSHSGRSDFELDVKIKFNK
                     KRH"
     gene            8713..9090
                     /locus_tag="KR231_002703"
     CDS             8713..9090
                     /locus_tag="KR231_002703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
                     /protein_id="HBH0005067.1"
                     /translation="MKEEILIEKLLRAELIVMEYLWKKDTLMPKKEIVKEIKQIYGWH
                     KSTIKILLKRLIDKGYLARDIIKFQSYYKIIIDNEEYYAFKKKVLKSSKSRKIMRSLT
                     TTHKNVSKEKLDSLEEYYKNLKE"
     gene            9195..9578
                     /locus_tag="KR231_002704"
     CDS             9195..9578
                     /locus_tag="KR231_002704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015984867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
                     /protein_id="HBH0005068.1"
                     /translation="MKISKLPEAELKVMRYIWEANKVLTSRELVAAMEEKYEWNESTT
                     FTVLKRLERREFLSTEKIGKLTHYNILVKEKKYLRFETKEFLKNIHKNSISSLISALH
                     SKDDEVDEDKLIELEEHFKNLKEKE"
     gene            9763..10347
                     /locus_tag="KR231_002705"
                     /pseudo
     CDS             9763..10347
                     /locus_tag="KR231_002705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896033.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
     gene            10373..10786
                     /locus_tag="KR231_002706"
     CDS             10373..10786
                     /locus_tag="KR231_002706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBH0005069.1"
                     /translation="MKKIILASHGDFSKGLLNAVKMIVGDLADCVSSYGLYPGQSASD
                     FALELEKTISEDKECEYIILSDLYGASVCTAMLRLTNLHNVRLFSGMNLNMVLELLTR
                     FSDELTVEDIDQLVEESRRGIQSVTLQIKEEEEVF"
     gene            10790..11533
                     /locus_tag="KR231_002707"
     CDS             10790..11533
                     /locus_tag="KR231_002707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane biogenesis protein"
                     /protein_id="HBH0005070.1"
                     /translation="MKKKGILSVFKSKKPIIAMIHLKGDTPEDIFERAKKEITIFEEN
                     GVDGIMLENYYGNYYDLERILEYVSKANLSIPYGVNCLNVDTMGFELATKYNASYIQV
                     DSVVGHVKPRDEATLEEFFKLQRSKCPAYLIGGVRFKYQPVLSENDVEEDLKIGMTRC
                     DAIAVTENATGQETSMEKIELFRKNLGDFPLVIAAGVTLENAKKQLKLGDMAIIGSYF
                     KDNYKDFGDVSVEHVKTFMDEIKKIREEL"
     gene            11533..12003
                     /locus_tag="KR231_002708"
     CDS             11533..12003
                     /locus_tag="KR231_002708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBH0005071.1"
                     /translation="MIKLVRVDHRLIHGQVAFTWTKFLSTDCILIASDDLLKDELRMA
                     GLKMAKPSNVKLVMKSIADSIKALNSGVTDKYNLLILCESVEDVYRLAKEVKAIKSIN
                     LGGTKSDDNRENISKAVHVSKDDIKMIKELDSEGVNVFVQLVPDDDATNVMKLI"
     gene            12020..12778
                     /locus_tag="KR231_002709"
     CDS             12020..12778
                     /locus_tag="KR231_002709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBH0005072.1"
                     /translation="MEFTQVILITLIAFFAYMHSFVGSTMHNRPIVVAPLVGLALGNL
                     HTGIVIGSTLELVFMGAFPVGASNPPDFVSGSIIATAFVILTGQDVSAAVVLAVPIAT
                     LVLLIDNFLMTVVLTWGAHIADRYAEEGNIEGVERVQLLFGIGNKLILAIIVGIGFSL
                     GVPVIEKILSFIPSYVTHGMDVAAGVIPAIGFAMLARMMLNKKTVAFLLLGFILVAYL
                     NITVTGVALFGLAIALIYVNFVGEKEVIVDDNEF"
     gene            12762..13604
                     /locus_tag="KR231_002710"
     CDS             12762..13604
                     /locus_tag="KR231_002710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HBH0005073.1"
                     /translation="MTTSSKKLETISPDSKITRKDFWKCFRRSLTLDSSWNYERMQNI
                     AYAYMMAPIIRRLYKDDKEKKSKALKRHLEFMSVTPHISTLLVGISGAMEEENAKNKE
                     FDANSINAVKSSLMGPVSGIGDSFFWGTLKLIAAGVGIALASQGNIMGPILFLLIINV
                     PHFIIRYICLDKGFKYGTQFFKDVSGSSIVSKVMEAASMLGLMVIGGMTASNVMLKLS
                     VNVGSGEWAEPIQTYLDQIMPCMLPAMIFGIMYWLLGKKVKTTTILISVMIICIVLAA
                     IGVV"
     gene            complement(13764..14669)
                     /locus_tag="KR231_002711"
     CDS             complement(13764..14669)
                     /locus_tag="KR231_002711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HBH0005074.1"
                     /translation="MDFKQLEVFVAVAKHQSFSKAARELFLTQPTVSAHIQNLERELE
                     TVLINRSNKVITLTKSGEILYEHAIYILNNCKRAIYDIKEYSGKIEGIIDIACSSIPE
                     TYILPDFMKSFSMSYPDVKFSISHYDSQYAISEILNERISFGLVGSKINNPQIEYLDL
                     LDDELVLITPSDFKIDNKNNCIDIGELAYLNFIMRKEGSGTRNLILNTLSKNNFPVSK
                     LNVIAHVESNEAIKEMVRLGLGVSFISYISAIDYLNAGKIKCYKIKDVDFTRKFFFIY
                     SKKKTFSPLEDKFLNRLCEYFEIII"
     gene            15031..15765
                     /locus_tag="KR231_002712"
     CDS             15031..15765
                     /locus_tag="KR231_002712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0005075.1"
                     /translation="MKLKRSLVCVTILGIILVGCHKENTKEKNQVASKATQQKTMTKV
                     QNDVNEIMNKDYKYIIKNMGIPYNTFYYIKPKVLKESNTMQDINTSSYMTLVYPKYTG
                     NDELDGSALYVDINENKVVNVETNSFSSQGISVIDAESSIVIEKSDHEKSAVSLENFR
                     HIDLGEYVGVEDSRINEIVGDANYDLTAYNHEGSKVVKSYRLKEDNKILKKEVLTISI
                     VDNKIKSIKTIESDKIVKIIKGTLLE"
     gene            15976..17157
                     /locus_tag="KR231_002713"
     CDS             15976..17157
                     /locus_tag="KR231_002713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdopterin molybdotransferase MoeA"
                     /protein_id="HBH0005076.1"
                     /translation="MIELEDAIKIIEKNVLPINRVKIVNLIDAVNKVVAEDIYSTIDS
                     PPFDRSPYDGYAYNANSENRNLKVIGTLYAGDVFNRVLNKNEAVKIMTGGKIPQGANC
                     VIKKEDVTVIGDMITLNIKLKEYDNYIFKGEDIKKGQLIINKNQNIGYDGIGVLASLG
                     ISKVTVYDDLKVGILNTGTELQDINETLENGKIYDSNRYTLYSRLLKLGIQADTICNC
                     SDDILELEKKVKNMLQSVDFLITTGGVSVGDKDLIPDVFKKIGATELFWKINIKPGGA
                     CYVGTLGEKLLFGLSGNPHAAIVVFDNVIVPVIEYLTYKKGTHHIKAIFKGEFNKFSN
                     KDRFVSGKLYTSEGKLYVELNDKKDAKARLSATLRSNCMIKIKKNETIKENQLVDVVI
                     R"
     gene            17141..17713
                     /gene="mobB"
                     /locus_tag="KR231_002714"
     CDS             17141..17713
                     /gene="mobB"
                     /locus_tag="KR231_002714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdopterin-guanine dinucleotide biosynthesis
                     protein B"
                     /protein_id="HBH0005077.1"
                     /translation="MLLLDSFMKGHNFMYNILSVVSYSGVGKTTLIEGIIKELNKKGY
                     RVGVIKHTCHDFDMDEEGKDTYKHRKSGARKVCIISDKRVAYIEELKEKNPLYKMIQL
                     YEDMDLIIIEGYKNYRFKRLEVTRKGKYEDILSNKSDLIGIVSDIEYKLNIEQFNLND
                     YKNISKYIESCIKNEILSISNVEIKNILKE"
     gene            17832..18107
                     /locus_tag="KR231_002715"
     CDS             17832..18107
                     /locus_tag="KR231_002715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBH0005078.1"
                     /translation="MKKILVACGAGIATSTIVCDRVERLVKENNIQAEVEQCKIAECS
                     TKQEGADLIVSTTILPTTYDIPTIKATGYITGINTTALDKKILNALK"
     gene            18362..20062
                     /locus_tag="KR231_002716"
     CDS             18362..20062
                     /locus_tag="KR231_002716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH0005079.1"
                     /translation="MIKQFVKYYKPYKKIFTLDLIAAFLFSLCDLVYPMITRNIMDDV
                     VPNKNLRMLVVFAVALILIFIAKAGLNYFMQYWGHVIGVDMQADMRNEVFTHLQRLPN
                     TYFDNNKSGVTMSRIVNDLMDITELAHHGPEDLFISIVMLVGSFFILIDINIPLTLII
                     FAILPFIIWFAIAKKDKMNIAFMKSRVTIGDVNATLENSIAGMKVTKSFCTEKEELNK
                     FVRSNKLFRRARQDSYKVMAEYYSGMNLYMDILEWVVVIAGGYFTYIGKITLGDFAAY
                     ILYVKMFIQPMKKLINFTEQYQNGMTGFKRFIEIMEQDHQKEAKNPIELENVKGDIEI
                     ENISFTYEDKTQVLDNLSLSIKAGKTIALVGPSGGGKTTLCNLLPRFYEFDKGDIKID
                     GKSIKDVSLKSLRKNIGIVQQDVFLFTGTIRDNILCGNPNATDEEMIAAAKKARIHDF
                     VETLPDGYDTYIGERGVKLSGGQKQRISISRIFLKNPPIIILDEATSALDNVTEREIQ
                     ESLEELSKDRTNLVVAHRLTTIKNADEIIVLTDKGIEERGTHEELVNKNGVYSRLHNN
                     "
     gene            20425..21612
                     /locus_tag="KR231_002717"
     CDS             20425..21612
                     /locus_tag="KR231_002717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0005080.1"
                     /translation="MEAITAFCLVLVSLTIGDIVSAKTKAFVPSVFVSAIIFIVGFWT
                     FFPENIVDLAALGTPLAQLGMLLLITHMGTMMSIKELAGQWKTIVIALAGIVGICVGA
                     LALGTVVFGWDTAVIATPPLTGGLVASIMMADAATAKGLASLSVLAILMYVAQGFAGY
                     PITALMLKKEGKRLLSDFRSGKVTVNTDEEKVKDLPEQKSRFKIIPDLPEKYDTTYMI
                     ILRLGFVAWLAVQFTNLTNEVVSRYVICLIFGVIASELGIVDRKPLNKSGSFGWLMTS
                     LMAFIFAGLAKATPAMLVEMAVPLVGIIIFGVIGMGIFSIIVGKLLGESKEMAFSVSL
                     TSLYGFPPNYILTEEAVKALAETPEEKEFLMDKMLPKMLVGGFTTVTIASVVIAGIFV
                     NLI"
     gene            21672..22835
                     /locus_tag="KR231_002718"
     CDS             21672..22835
                     /locus_tag="KR231_002718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HBH0005081.1"
                     /translation="MDIKEITKSYKDYVIKLRREFHENPEKSMEEVRTSKRVKEELDK
                     IGIPYVSAGGTGVIATIKGANPGKTVALRGDMDALQVVECTDVEYKSKNEGLMHACGH
                     DGHTSMLLGAAKVLNDIKDSINGTVKLFFQPGEEVGKGARAMIQDGAMEGVDSVFGIH
                     LWTDVESGTISVEEGPRMASADFFKITVKGRGGHGSLPHQGVDAVLASSAIVMNLQSM
                     VSREVSPLEPLVVSVGVLNSGTRFNVIASEAVLEGTIRLFNPELRKQIPGILERIAKS
                     TAEAYRADAELEYGYLTPAVINDKECSKIATDAAIKLFGEDCITLFEKVTGAEDLAEF
                     MNIAPGALAFVGARNESKGACYPHHHGCFNIDEDALEIGTALYVQYAVDFLNK"
     gene            22986..23789
                     /gene="zupT"
                     /locus_tag="KR231_002719"
     CDS             22986..23789
                     /gene="zupT"
                     /locus_tag="KR231_002719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861091.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc transporter ZupT"
                     /protein_id="HBH0005082.1"
                     /translation="MNNVIFAFLITLLAGLSTGIGSCIAFFAKKTNTKFLSISLGFSA
                     GVMIYVSMIEIFPKAQDALTKSMGEKLGSWSTVIAFFIGMAIIAVIDKLIPQEENPHE
                     IKKMENIEEKNIKKNKSLLRTGIFTAMAIAIHNFPEGLATFISALDDVTIAIPIAIAI
                     AIHNIPEGISVSVPVYYATGDKKKAFYYSFLSGMSEPLGAIIGYVLLRNFLNDITLGI
                     VFAIVGGIMVFISLDELLPSAREYGEHHLSIYGLIAGMGVMAISLLLFK"
     gene            23885..24445
                     /locus_tag="KR231_002720"
     CDS             23885..24445
                     /locus_tag="KR231_002720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2812 domain-containing protein"
                     /protein_id="HBH0005083.1"
                     /translation="MSAMEKKIKFKFDWYSSPDKIEKWLEDIEAKGYNLYKINKFGGI
                     FYFHKGSPRKIKYTVDYYYDVENNYFDEHKSNGWNLVFRSIGSFMGTSAWYIWSKEYK
                     DIPPKLYSDSDKKNKVKSILFMNMFIFFMLVVIFIYLLNIEIRNLYSGYGASVTAIVL
                     QIILLILYAVQLYRRLMYYLRLKKFK"
     gene            24695..25408
                     /gene="rgbR"
                     /locus_tag="KR231_002721"
     CDS             24695..25408
                     /gene="rgbR"
                     /locus_tag="KR231_002721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator RgbR"
                     /protein_id="HBH0005084.1"
                     /translation="MIKIAVCEDEKETQLLIEDYLENILKDISIEYEIQKYISGEELL
                     ESNLKDIDILLLDIKMEKLNGMDTARKIREVDNEMEIIFVTSLIDYVQEGYEVRAYRY
                     LLKPIELEELKKHVLTCIKDIEINKESHITIKNKSNTYKIYLNEIKYIEVQKKDMLIH
                     TINKNFDIKYSLGKIEKELNPYKFIRCHKSFIVNLRYVENIKPNTAILESGEEVPISR
                     YRYKEVKEKFLKFLGDTIC"
BASE COUNT        10250 a         2588 c         4437 g         8239 t
ORIGIN      
        1 gatggagtat tagacattgc aaatacaatg ataaatgagg ttaaatctaa tctaacaata
       61 aatagtaaca gtatagtagt gagaggtgag gtagttggat aaagagatta atctaataaa
      121 ttacttacca caaattctac aagataaaga agaatatata aaagtattta atgtaggaaa
      181 taaagaaata aaaatattac atgataaatt aaaggaccta tcaaatgacc agtttttaga
      241 ggacctaact ataagtggta taaaaagatg ggaaaagata atgtctataa ctcctaaaag
      301 taatgagagt ttagaagata gaaggtttag gatttttagt aaatatataa gtaaattacc
      361 ttactcagag agatttttaa ggaattggct agatagtata gttggagaag gtaattatga
      421 gttaactatt aataatgcta cttataatat acatcttgaa agtgatgcta gaaatcaaga
      481 ttggtttgag gaagttcatt cttttgtaag taatattaag ccatgtaata tgactttaga
      541 ttacactaga gtgcttataa gcaaagacaa ttatatgaat tttggtataa caaccctaat
      601 gggtcaagaa ataactatat acccttggag tccaccagat atagaaactt atggagaaat
      661 tgatgtatta actggcaatg gagttggata ccaagagata acaatatttt aggaggtgat
      721 atattggcta tagataaaag ttattacact ataattacag atgtaggaaa agcaaagata
      781 gcaaatgcaa gtgtcacagg taataaagtg ggatttgtaa aaattcaact tggtgatgga
      841 ggagggagtg aatatactcc aactgagagt cagacagctc tcaaaaacgt ggtatgggaa
      901 ggcaatattg gaaatacaac tacagatgaa actgcaccaa attgtataat attagagagt
      961 ttaataccat caagtgtagg cggatttatg ataagagaaa taggatattt agatgatgaa
     1021 aataatttaa ttgccatttc taaatacaaa gagtgttata aaccttctat agaacaaggt
     1081 gcagtggtag acatgaaggt taaaactgtg cttattgtat ctaatgtaaa taatatagaa
     1141 cttaaaattg acccaacaat aatctttgca acactcaaag atatacaaga cttagaaact
     1201 aaaataggta ctgttaatac taaaatagat acaactaaaa cagaattaac aaataattta
     1261 gaaactgcta aaacagagtt aaatactaga attgacacag aaaatgagaa acaaaatatt
     1321 aaaattgacc aacttattgc aggtggctct aatgtggcat ctactcaaac aataacaatt
     1381 gacgattggg ttgaggatgc agaaaatgga ttcaaagcaa ctgtaacaca tagtttatta
     1441 acacagagaa tagttgtaaa tattatagat gctactacaa aagaaaatgc agttacaaac
     1501 tttaaaatta tagatgataa ttctatagaa gttagaagtg aaacaaggtc agaattaaac
     1561 gtttatgtga taaatggaaa tgcagaaact cattttatta atgcaactgt agatgataac
     1621 agagtgtctg aaatgactac ttattcatct aagaaaatag aggattctat tagcagtata
     1681 cagcttatag ataccagtat aagtattaca gatgctaatg atagatttac aagtgataag
     1741 ttagatggag tattagagga aataatggta gaaataagtg gtcaaagaac taaaggaata
     1801 actatagtga ataatttaat agatatgata taagcgaggt gaaaatatga cagaaaaatt
     1861 aactgaaaat gctagtttag gggaacttat ggcagcatta gaaaatgtac aaactgattt
     1921 tcaaactggt aaaaataata tatctagtgc attgggtagt ccttttattg gaacagataa
     1981 atttggtaca actaaaacaa aaatagaaac attaaaaaat gtattagtgg agacgattaa
     2041 ttctaaaaat gtttcagcaa catcatctga aacatttact aatttgattg aaaaagttaa
     2101 ctggattttt caatcaatag aaattttttc tttaaaaaat agaattcaag ctacaacttt
     2161 aaacactcct agcatcgttt acaatgaagt atctagtata aaaggcacat taagattcac
     2221 aggcgaactt aaagcgtcta aaatgcgtgc tgattatgca acagcaaaaa tagagatact
     2281 atgtggaaac cgaaaagaat acttttatgt tactgacgat actcctagtg catcttcttc
     2341 ttttgtaaga tttacaaaag atattattgt tgagaatggc atggatataa aagtacaaat
     2401 attattaaca tctgtaggag caggaaattt agatggttca tatgcagctc gtgcagaaat
     2461 agaaaaatta acaatattaa ggtaggaata aattatgaaa aaacaagtat attataattc
     2521 tttagatgaa aaagaaaaaa taattagtga aaactctaat ttatatgtta tagaaatata
     2581 tgaaacttta aatgaaaatt atttagtgtt atcaagtagt ccaatacaag atgaaaaact
     2641 tagttatgaa gaattagaaa atgaattatt aattatgact aatgaattac aaggaggatt
     2701 gttataatga atataaataa tgttgtggta agaatattag cagaaagaat attaaatgga
     2761 gggttaaacc ctttgaaaaa tagagagttt caacttgatg atgtaactaa cacagaatac
     2821 agaaaagcag tagaggatta tattataaaa aatagtggag tagtagaagg aatagaacca
     2881 acagcgtagt aggttctttt tttattgaaa gaaggtgact aaatgacttt taaagagtta
     2941 gttaataaag ttagaaatct tgtattagaa gcaaagaatg taactataga agatacagag
     3001 aataacttta caagtgataa tgtagaagga gcattaaaag aggtttttca aaatggagtt
     3061 aatgctaaaa ataatgtagt aacagcatta aactccaagg gagcagaggt tactacaagc
     3121 gatacatggg aagaaataaa gaataaaatt gatataaaag aggggagatt agatttaaga
     3181 gaaacaatac ttgcaaatag ttattcttca tatttggtta caaatggtgc tataaaatat
     3241 attgaaaaat atagtgggag tttaaaagca ttagaatatg aagaacccta tttttatgca
     3301 attaaaggta cacatttaat taaaattaat gcaattgatg aatctgtaat ttttgatatt
     3361 actttagcca atgctaactt ctcatgtatc tgtgttactc aagagtattt atttatatct
     3421 gacaatacta aattatataa aataaataag ttaacaggaa atgaagcaca gtcaatagaa
     3481 ggttcttatt ataagctatg tacttatggg gaatttattt atggaatata tggagatgag
     3541 acttcttcaa tacttcacaa aataagaata tcggatatgt atataatgct aactaaagat
     3601 atgtcctctg atagaattta tgactttgaa agaggcaaat ttgtatgtaa taataatggt
     3661 atttatgcta caacagaaca ctcaaattca agtggtctta cagaatgtta cctaactaaa
     3721 ataaattttg attttagtgt tgcgaaaagt tttagaattg gaggatattt atatgaaaaa
     3781 aacattaagt ttttaaatga ttttgttttt gtatctgata gtagcagaag catagaagtt
     3841 gagagtggta aaaaaagtgg attagcaaaa tatgatgcaa atctaaattt gattacttat
     3901 ggtgggtcag atagatatga aaattttgaa atatataatg gatatatata tacatttaat
     3961 tcactttcta gtagcccatt tataaaaata aatttaaata ctcttaaaga agttaatagc
     4021 taccgaacgc tcattaacac aaatcctcaa aaaggtatgt ttataataaa caatataatt
     4081 ttttttattg gtggtggcat tcacagaaat atattatcaa aaaaggttta ttcagatgaa
     4141 aaaggagagg aattatgatt tatttaggaa atttactaga cacagaggaa caaaatataa
     4201 aatatgttgg tatgatacac tatgaaccaa atttgttatc ggaggaaaac ttaaaacaag
     4261 gaattttggt cgaggaatta ccaacaccaa aatacacaga aaataaagaa acaaagttat
     4321 ttataaatat agatactaaa gaggttttct atagatatac agatattaaa agtagcatag
     4381 aagataaagt aaattctaca gaacaaacaa tagcagattt aacatttcaa ttaatgagta
     4441 atggggtgat atagtatgaa ttggtataag ataataacag atttctataa taatggtaat
     4501 tggactaaag agcaagttaa aacagcggtt acaaagaata agataacagc aagtgaatat
     4561 aaagaaattg taagagagga ctatatagcg tagttctttt aaatagactt agataatttc
     4621 taagtcttat tttaatgcag aataaggagg aaatatgaac gtaacaatag tttttttagc
     4681 aacaaatata tttataaaat tagtaatatt agcaatagca tttgatacac tgttaggttg
     4741 cttaagagca ataaaaacac atcagtttaa tagctctttt ggaataaatg gaggaataag
     4801 aaaagtagca atgatagcat gtatattttt tctagcagta gttgacattc ttacaaagtt
     4861 taacttttta tttatgttgc cacaagattg ggttgatttt ttgcgattaa atcatcttgg
     4921 aatatctgaa tttttctcta ttttatttat tctatatgaa agtgtaagta tattaaaaaa
     4981 tatgtactta tgtggattac cagttcctaa acgattaaaa gagaaaatag gtagtttatt
     5041 agatactatg acagatgaat taaatgttaa aggaggtagt aaataatgaa aatatgtata
     5101 acagtaggac acagtatttt aaaaagtgga gcatgtactt ctgctgatgg agtagttaac
     5161 gagtatcaat acaacaaatc tcttgcacca gtattagcag atacatttag aaaagaaggg
     5221 cataaggtag atgtaataat atgcccagaa aagcagttta aaactaagag tgaggaaaag
     5281 tcttataaaa tacctagagt taatgctgga ggatatgact tactcataga actacattta
     5341 aatgcaagtg atgggcaagg aaaaggctca gaggttctat attacagtaa taaaggtcta
     5401 gagtatgcaa ctagaatatg taagaaacta ggtacaatat ttaaaaacag aggtgctaaa
     5461 ttagataaag gattatatat tttaaatagt tcaaaaccta ctgcaatact aattgaaagt
     5521 ttcttttgtg acaataaaga tgattatgag aaggctaaga aatttggata tgaaggtatg
     5581 gctaagttaa ttgttgaagg tgtattgaat aagaatatag gaaatgatgg agttaaactg
     5641 atgtacaaac atacaatcgt ttatgatgga gaagttgaca aaatccctgc aactgtagtt
     5701 ggctggggtt ataatgatgg aaaaatactg atatgtgata taaaagatta tataccaggt
     5761 cagacagaaa atttatatat tgtgggtgga ggagcatgta ataagatagg ttctataacc
     5821 aaagaaaaat acacaatgat aaagggtaat gatagatttg atacacttta caaagcatta
     5881 gattttattg atagataaaa ggagtatagt taatgtattt tacattttgc ttatacttta
     5941 tgccaatatt acgacaattt ataaaataaa aaatgatata ttaaagataa tcataagcca
     6001 ttttaaaatc caaaaaacta ggtgtataaa cagttaacaa atatatatat tgataaaata
     6061 atggaggtga aataaaaaat agtagtgcaa taacaataat tctaatgtag aataatatta
     6121 aataatatta ttttaggggg atttaaaatg gcttatgaaa atggaactga ttttatagat
     6181 tattttcctg attgtataga aaaatataag gaagataata aaatctttga gaaggcaata
     6241 ttattactca atctgtatat gcaaaaacca acatggccac attgtgttaa tgagtacaag
     6301 agccaggcgg aaaaaatttt aggtgaagac ccagagttta taggaaagta tggtatacaa
     6361 ttaagaaaat tttatgatga agatgaaaat gcaaaagtaa gtaaggaatt taaaaatgat
     6421 ttgtataatt tttctaagag tacatatgat atactagata atgtttattt ttcaaaaagt
     6481 catcctttta atctttcatc tatttattca acttctagag atgatgattt tataataaaa
     6541 atatttagat atgataataa ttttcttgaa ttagagatgt caaagagaga agtagagtca
     6601 ttaataaact atttatctga tttattaaag gaagaatagt atgttaggag caaaaaagaa
     6661 aaagagttta atttattgag ttttaatgaa aaaaagatag aaaaacataa atgtaaaaat
     6721 tatcataatg attcttcgaa agataaatac aaatatagtc aaagtgaatt tatagctgct
     6781 actttaaagg aggcagatga tatgaatgaa gaagaaagaa gaatactaga agcagaaaaa
     6841 agaatattag agactgagaa aagagtgcat caagataaca aggaagtaaa agaaagtata
     6901 gataagcaat ttaatgacat aaagggtatt tttaaagaat acaagaatga tttagacaaa
     6961 gatagaatag aactaaaaaa tgatttagct agagaaagag ctgagttaaa aagtgattta
     7021 aaagaagcta taaacgaaca taaaaaggtc acagaaaagg atgtaagtga aataaagaat
     7081 agtatgaaag gtatagaaga tagaattgat tcaactaata aatggattat tggactatgt
     7141 ataactacta taataggaat tgctacaatg gctattacaa taggtatatc tatatggcca
     7201 aagtaacaca aaaagaggta actagaatta aaatagttat ctctttttat acttaaacaa
     7261 aacattgaaa aaatagtaaa aaatattaac aggatacata aaactatagt ataacctgta
     7321 ataataaaac gaacgaaaat tatcatacta aaacataaga catgctataa ttgtattaga
     7381 taaatgcttg aatatatacc aaaagtactc tttttataag agtgcttatt tttttgaaat
     7441 tcatcaacat ataaacaatc aagaacatta ctcaacacac cttaaaattg atttaaattc
     7501 tttttcatac acaaagttat atgatataat aaaaaagtaa atatgtaacc ccaacacatc
     7561 tttactaagt caaacattat tatatagagc attcttcatt atggagagtg ctttttcatt
     7621 tctttgaata atcatgttga ttatttataa tattttcatt taatttatct ttatctatca
     7681 aatttaatgc acaattaata caaatgttag ttttcatatg acttttctta tgaaaagtaa
     7741 tatacttatt atcatcttta tttattcctt tattacagta atcacataat atagtcttag
     7801 tcatattttt attcctttca ttttatattt tccataatta agtttaacat atttagtata
     7861 tacctatgta tatatattta aaacaatgtt ttttattgca atatagaata tattgtataa
     7921 ataaaaaaaa tggagaatag atatttgata attgtaaaat tatgttataa ttaaaatgca
     7981 agaataatct tgtggaacta caatctaaga gtggagcttc attttctaca ttccatccct
     8041 taaaaggaag gaggtggaga aatgagcgaa tttttactag gagtgttagc tagtttaaca
     8101 gctagcttta ttacatatat tatttccaga aaagtaaaaa gccactctgg caggagtgac
     8161 tttgagcttg atgtaaaaat caagtttaat aaaaaacgac attaatattt agttaatgaa
     8221 acttcactct aggctaatag attgtagttt ctttttttgt ttttgatacg aatttacatc
     8281 tttattatat cgcattttga gaaaaaataa aactatgaat attagaaata tattttattt
     8341 tatctctaag tatatatatt attagccacc taaaaaactt tcacaaaaac aaaaagagta
     8401 tatgtttttg ataactggat gatataactt ataactcatt ttacaattct tagttcatat
     8461 atatttatgc cactaaattt ctctagtttt gccgatttag ttttattcta caactaaaat
     8521 aatacaatag aattagttat tattcaacaa gattgtttga aagttaaata aatttataga
     8581 tatgaacatt attttacact taaaaaaaca gactaaatat gtagaatatt tggtaaaact
     8641 tacctctagt ttttgtctta aaaagctcct attattaatt taagttagac gaatttaagg
     8701 aagtgacata aattgaaaga agaaatatta atagaaaaat tattaagagc agaattaata
     8761 gtaatggagt atttatggaa aaaggacact ctaatgccta aaaaagaaat tgtaaaagaa
     8821 ataaaacaga tttatggatg gcataaaagt acaataaaaa tactactaaa aaggctaatt
     8881 gacaaaggtt atttggctag ggatattata aaatttcaat cttattataa aataataata
     8941 gataatgaag aatattatgc ttttaagaaa aaggtactaa aatctagtaa aagtagaaaa
     9001 ataatgcgtt cacttaccac tacgcataaa aatgtaagta aagagaagtt agactcatta
     9061 gaagagtact ataaaaactt aaaagaatga tatggtaaaa attggatgga attatttacc
     9121 ttaattctct tgtttgtaaa actttattga tatagaattt aacatataca taaatcggta
     9181 aaggggtgta gactatgaaa attagtaaat taccagaagc ggaattaaaa gttatgagat
     9241 atatttggga agctaacaag gtattaactt ctagggaatt agttgctgca atggaagaaa
     9301 aatatgaatg gaatgaatca acgacattta cagttttaaa aaggttagag cgaagagaat
     9361 ttttaagcac agagaaaata ggcaaactta cacattacaa tatactagta aaagagaaaa
     9421 aatatctaag gtttgaaacg aaagaatttt tgaagaacat acataagaat tcaatttcaa
     9481 gtttaatatc agcgttacat agtaaagatg atgaagtgga tgaagataaa ttaattgaac
     9541 tcgaagaaca ttttaaaaat ttaaaagaga aagaataaat aaagattatt ttaggtggca
     9601 aattattttt gccacctttt ttgccaccat gacagtttaa taaaataaaa tacaaataaa
     9661 gaaatataaa taaaatagaa taaagaaatt gttttagata ggttgtaaat aaatgtactc
     9721 ataaaaacat aaataaatat aaataaacat aaataaaata taagaatttc tgtgagaaat
     9781 gcacttaatg aacttgtaaa agaagatata ttatgtaaaa aacgtggtaa agggacttat
     9841 gtaacaatac cagagagaat agaagcaaca tgtgcaggaa atagttttac taattcttgt
     9901 catcgtatta atgcaaaacc aagtaccaaa ataatctctg ttttaataaa aaaagcagat
     9961 aagcaagtag ctgaagcttt aagtattgaa ctagaagaga aggtaatatg tattaaaaga
    10021 cttagattaa tagatgaagt acctgttatt tttgaagttg actattttag aatagattac
    10081 atgtttttat taaaagaaga attagaagat aaatctttaa tggaggttat atctaataat
    10141 ataagcacat tacctaaacg agtagaaaat atatttgaag taaaacattc aaacaaagaa
    10201 tattctgacc atcttaaatg tgcaagtaat atgccactat tgaaagtaag acaatcggtg
    10261 tatacagaaa ataatgatgt cttatattac aatgagcaat ttataagaag tgataagtac
    10321 aaatatgcag tatcagcaga aatataatct ataatttagt aggaggatga gtatgaaaaa
    10381 gataatatta gcatctcatg gagacttttc aaaagggctt ttaaatgcag taaaaatgat
    10441 agtaggagat ttagcagatt gtgtcagttc gtatggtttg taccctggac aaagtgcttc
    10501 agattttgct ttagaattag aaaaaacaat atcagaagat aaagaatgtg aatatataat
    10561 tttatctgac ttatatggag caagtgtatg tacagcaatg ttaagattaa ctaatctaca
    10621 taatgttagg ttattttctg gaatgaattt gaatatggta ttagaacttc ttacaaggtt
    10681 ttctgatgaa ttaaccgttg aagatataga ccaattagtg gaagaatcta gaagaggaat
    10741 acaaagcgtg acattacaaa ttaaagaaga agaagaggta ttttagttta tgaaaaaaaa
    10801 gggaatatta tcagtattta aaagtaaaaa accaattata gcaatgatac acttaaaagg
    10861 agatactcca gaagatatct ttgaaagagc taaaaaagag attacaatct ttgaagaaaa
    10921 tggtgtagat ggaataatgt tagaaaatta ctatggtaat tattatgatt tagaaagaat
    10981 acttgaatat gtatcaaaag ctaatttatc aataccatat ggagtaaact gtttaaatgt
    11041 tgatactatg ggatttgaac tggcaacaaa atataatgct agttatatac aggttgattc
    11101 tgtagtaggt catgttaaac ctagagatga agctacttta gaagagtttt ttaaattaca
    11161 acgttcaaaa tgcccagcgt atttaattgg aggcgtacgt tttaaatatc agccagtatt
    11221 atcagaaaat gatgttgaag aagatttaaa aataggaatg acaagatgtg atgctatagc
    11281 agttacagaa aatgctacag gtcaagaaac atcaatggaa aaaatagaac tgtttcgtaa
    11341 aaatttagga gacttcccat tggttatagc tgctggagtt acattagaaa atgcaaaaaa
    11401 acagcttaaa ttaggagata tggcaataat aggaagttac tttaaagata attacaaaga
    11461 ttttggggat gttagtgtag aacacgtaaa aacattcatg gatgaaatca aaaaaattag
    11521 ggaggaatta taatgattaa attagtaaga gtagaccaca gacttataca tggacaagta
    11581 gcatttacat ggacaaagtt tttaagcaca gactgtatat tgatagcaag tgatgactta
    11641 ttaaaagatg aattgagaat ggcaggactt aaaatggcta aaccatctaa tgttaagtta
    11701 gtaatgaaaa gcatagcaga ttctataaaa gcacttaact caggtgttac tgataaatac
    11761 aacttattga tactttgtga atctgtagaa gatgtttata gacttgctaa agaggtaaaa
    11821 gctattaaat ctataaacct tggtggaaca aaatcagatg ataatcgtga aaatatatct
    11881 aaagcagtgc atgtatcaaa agatgatata aagatgatta aagagttaga ttcagaaggc
    11941 gtaaatgtat ttgtacaatt agttcctgat gatgatgcta caaatgtaat gaaattaata
    12001 taattttagg gggatgaaaa tggaatttac acaagttatt ttgataactc taattgcatt
    12061 ctttgcatat atgcatagtt ttgtaggttc tacaatgcat aatagaccta tagttgttgc
    12121 accacttgtt ggtttagcac taggtaatct tcatacaggt atagtaatag gttcaacatt
    12181 agaattagta tttatgggtg catttcctgt tggggcaagt aatcctcctg attttgtgtc
    12241 tggttctatt attgccacag cgtttgtaat attaacgggt caagatgtat cagcagcagt
    12301 tgtacttgca gttcctatag caactctagt attgcttata gataacttct taatgacagt
    12361 agtacttaca tggggagctc atattgctga ccgttatgca gaagagggga atattgaagg
    12421 cgtagaacgt gtgcaattat tatttggtat aggaaataaa ttaatattag caataatagt
    12481 aggtatagga ttttcattag gtgttccagt aatagaaaaa atactttcat ttataccatc
    12541 atatgtaact catggaatgg atgttgcagc aggcgtgatt ccagcaatag gttttgccat
    12601 gttagctaga atgatgctta ataagaaaac agtagcattt ttattattag gatttatatt
    12661 ggttgcttac ctaaacataa cagtaacagg agttgcattg tttggattag caatagcttt
    12721 aatatatgtt aactttgtag gagagaagga ggtaatagta gatgacaacg agttctaaga
    12781 agttagagac aatttcacca gatagtaaaa taacgaggaa agacttttgg aaatgtttta
    12841 gaaggtcatt gacattagat tcatcttgga actacgaacg tatgcaaaat atagcatatg
    12901 catacatgat ggcaccaata atccgtagat tatataaaga tgataaagaa aagaaatcta
    12961 aggctttaaa aagacattta gaatttatgt cagttactcc tcatataagt actcttttgg
    13021 taggtatatc tggagctatg gaagaagaaa atgcaaagaa taaagaattt gatgctaata
    13081 gtataaatgc tgttaaatca agtttaatgg gtccagtttc tgggatagga gattcatttt
    13141 tctggggaac attaaagctt atagcagctg gggttggtat agctttagct tctcagggta
    13201 acataatggg accgatttta ttccttttaa taataaatgt tcctcatttt attatacgct
    13261 atatatgtct agataaagga tttaagtatg gaactcaatt ctttaaagat gtgagtggtt
    13321 caagtatagt ttcaaaagtt atggaagcag cttcaatgtt agggcttatg gtaattggag
    13381 gtatgactgc atctaatgta atgttaaaac ttagtgttaa tgtaggtagt ggagaatggg
    13441 cagagcctat tcaaacttac ttagaccaaa taatgccatg tatgcttcca gctatgatat
    13501 tcggtattat gtattggtta ttaggaaaaa aggtaaagac aactacgata ttaatttcag
    13561 ttatgattat ttgtatagta ttggctgcta ttggagtagt ataaataaaa aaatcccaag
    13621 ttcatttgaa cgagggattt tttgactaaa ttaaataaaa aagaaagatg gttcataata
    13681 atttataagc atttatgtga tagttataat tagcttatta attagttata aactcaaaat
    13741 taagcactac tttattaaag ttattatatt ataatttcga aatactcaca taatctgttt
    13801 agaaatttat cttctaatgg ggaaaaagtt ttctttttag agtaaatgaa gaaaaacttt
    13861 ctagtaaaat caacatcctt tattttataa cattttattt tacctgcatt gagataatcg
    13921 atagctgaaa tgtacgatat aaaggacact ccaagaccta atctaaccat ttccttaata
    13981 gcctcatttg attctacatg agcgattaca tttaatttac ttactggaaa gttattttta
    14041 ctaagtgtgt ttagtattaa gtttcttgta cctgaccctt cttttctcat aataaaattt
    14101 agataagcca attctcctat atcgatacaa ttatttttat tatcaatttt aaaatctgaa
    14161 ggagtgataa gaacaagttc atcatctaat aagtctaggt actctatttg aggattattg
    14221 attttagaac caactaatcc aaagcttatt cgttcattta aaatttctga tatagcatat
    14281 tgagaatcat aatggcttat ggaaaatttt acatctggat aactcataga aaaactcttc
    14341 ataaaatcag gtaaaatata agtttcaggt atggaactac atgctatatc tataatacct
    14401 tctatttttc ctgaatattc ttttatatca taaattgcac gtttgcaatt attcaatata
    14461 tatatagcat gttcataaag aatttcacca gattttgtga gtgtaataac tttgttgctt
    14521 ctatttataa gaacagtttc tagctctctc tctaaattct gtatgtgtgc gcttacagta
    14581 ggttgagtta aaaaaagttc tcttgcagcc tttgaaaaac tctgatgttt tgcaacagca
    14641 acaaatactt caagttgttt aaaatccatt atttaatcct ccttaaatta tctaaaacta
    14701 ttataacata tttgataaat taatagtcaa aggtgatttt taaaatagaa aacctttaaa
    14761 tattcatgga gtttttgatt gtttaggaat aatttggtat aatgttgtaa ggtacttaca
    14821 ataaaaatat cgtaaattga attttcaaaa ttcaacttta aagtgttttt tattacagaa
    14881 aaattacaat tagcttctta atcttattaa attcaaataa atattatata attattttat
    14941 aatataataa atataattat tgaaaaaaga gataactgta aattgagata tagataaata
    15001 ctataaaatt taagaaagga ggattgattt atgaagttaa aaaggtcatt agtttgtgta
    15061 actattttag gtattatact tgttggatgt cataaagaaa atactaaaga gaaaaatcaa
    15121 gtagcaagta aagcaacaca gcaaaaaact atgacaaaag ttcaaaatga tgttaatgaa
    15181 attatgaata aagattataa gtacattata aagaatatgg gtatacctta taatacattt
    15241 tattatataa aacctaaagt tttaaaagaa tcaaatacaa tgcaagatat aaatacatca
    15301 agttatatga cattagttta tccaaaatat actggaaatg atgaactaga tggaagtgct
    15361 ttatatgttg atattaacga aaataaagtt gtcaatgttg aaaccaattc tttctcatca
    15421 caaggtatat cagtcattga tgctgaatct agtatagtga ttgaaaaaag tgaccatgaa
    15481 aaatcggctg tatcactaga aaattttaga catattgacc tgggagagta tgttggtgtt
    15541 gaagattcca gaataaatga aattgtagga gatgcgaatt atgatttaac agcatataat
    15601 catgaaggca gtaaagtagt taagagttat agattgaaag aagataacaa aatattaaaa
    15661 aaagaggtac ttacaataag tattgtggat aacaaaataa aatctataaa aactattgaa
    15721 agtgataaaa ttgtaaaaat aataaaagga actttattag aataaaatat tctaaagcat
    15781 atgatgctgt ttcaagatag aaggaaattt ctagctggga acagtttttt tattagattt
    15841 ataaaatttg aactgcactt atagataact attagttata attaaatata agataaaagt
    15901 atttccaact tttataatct ataatatatt acatagaaat atcttaaata aaaaatatat
    15961 tggggagtat ttaaaatgat agaattagaa gatgccataa aaattattga aaaaaatgtt
    16021 ttaccaataa acagggtcaa gatagtaaat cttatagatg cagtaaataa ggtagttgca
    16081 gaagatatat attcaacaat tgatagtcct ccatttgata ggtcacccta tgatggttat
    16141 gcatataatg caaattctga aaatagaaat ttaaaggtta tagggacttt gtatgcagga
    16201 gatgtattta atagggtatt aaataaaaat gaagcagtga agataatgac tggtggaaag
    16261 ataccacagg gtgcaaattg tgtaataaaa aaagaagatg taacagttat aggtgatatg
    16321 ataactttaa atataaaatt aaaggaatac gataattaca tatttaaggg tgaggatata
    16381 aaaaaggggc aattgattat taataaaaat cagaatatag gatatgatgg tattggagta
    16441 ttagcaagtc ttggaatatc caaagtaact gtttatgatg atttaaaagt tggaattttg
    16501 aatacaggta cagaactaca agatataaat gagactttag agaatggtaa aatatacgat
    16561 agtaatagat ataccttata ttcaagatta ttaaaacttg gaatacaagc agatacaata
    16621 tgcaattgtt ctgatgatat attggagtta gaaaaaaagg taaagaatat gttacagagt
    16681 gtagattttt taattaccac aggtggtgtt tctgttggag ataaagattt aattccagat
    16741 gtattcaaaa aaataggggc aacagaatta ttttggaaga taaacattaa acctggtgga
    16801 gcttgttatg taggtacatt gggagaaaag ctattatttg gtctttctgg taatccacat
    16861 gcagcaatag tggtatttga taatgtgata gttcctgtta ttgagtattt aacatataag
    16921 aagggaacac atcatataaa agctatattt aaaggagaat ttaataaatt ttcaaataaa
    16981 gatagatttg taagtggaaa actatataca agtgaaggta aattgtatgt agagctaaat
    17041 gataagaaag atgcaaaagc tagactatct gcaactctaa gaagtaattg tatgattaag
    17101 attaaaaaga atgagacaat aaaagaaaat caattagtgg atgttgttat tagatagttt
    17161 tatgaaagga cacaatttta tgtataatat attgtcagtt gtctcatatt caggagtagg
    17221 taaaactacg ttgattgaag gcataataaa agaattaaat aaaaaagggt atcgtgttgg
    17281 agttattaaa catacctgtc atgattttga tatggatgag gaaggaaaag atacttataa
    17341 acatagaaaa tctggggcga gaaaagtctg tataatatca gataaacgag tagcatatat
    17401 tgaagaacta aaagagaaga atccattata taaaatgatt caattatatg aagatatgga
    17461 cttgattatc atagaaggat ataaaaatta tagatttaaa agactggaag taactagaaa
    17521 aggtaagtat gaggatattt tatctaataa gtctgatttg ataggtattg ttagtgatat
    17581 agaatataaa ttgaatattg aacagtttaa tttaaatgat tataaaaata tatcaaagta
    17641 catagagtct tgtataaaaa atgaaatttt aagtataagc aatgttgaaa taaaaaacat
    17701 attaaaagaa taattttaag atgttcttct tatataaaat gatataatta tttatataaa
    17761 taaagatata agaaatttat caattttatt ttgagttata aaatattaaa gaaattgtag
    17821 gaggacaata tatgaaaaaa atattagtag cctgtggagc aggaatcgca acatcaacaa
    17881 tagtttgtga cagagtagaa agattggtta aagaaaataa tatacaagca gaagttgagc
    17941 aatgtaaaat tgctgaatgt tcaacaaaac aagaaggtgc tgatttaatc gtatctacta
    18001 ctatactacc aacaacttat gatataccta caataaaggc aacaggatat ataacaggta
    18061 taaatacaac agcattagat aaaaagatat taaatgcatt gaagtagttt tgtatttata
    18121 aaaaaaattt agtattaaat atagagttgt atctttataa aattttaaat atagagatat
    18181 agctcttttt atgttgtttc aagtatacaa ctatatgata taaatcttca attttatgaa
    18241 aaagattgtt attactttgt aagtttataa aagatttaaa gttattgtta tgttatacta
    18301 atttatgggt attttttaga agtactaata gaagtactaa taaaggaggg atttaatact
    18361 tatgataaaa caatttgtca aatattataa gccatataag aaaattttta cactagacct
    18421 tatagcagct tttctatttt ccttatgtga tttagtttat cctatgataa ctagaaatat
    18481 aatggatgac gttgttccaa ataaaaactt aagaatgtta gtagtttttg cagtagcact
    18541 tatacttata tttatagcaa aagcagggct taactatttt atgcagtatt ggggacatgt
    18601 tattggtgta gatatgcaag ctgatatgag aaatgaggta tttacacact tacaaagact
    18661 tccaaatacg tattttgata ataacaaatc tggagtaact atgtctagaa tagtaaatga
    18721 tttaatggat ataacagaac ttgcacatca tgggcctgaa gatttattca tttctatagt
    18781 aatgttggtt ggttcattct ttatacttat agatataaat attcctctta cgcttataat
    18841 atttgctata ttaccgttta taatttggtt tgcaatagct aaaaaagata agatgaatat
    18901 tgcttttatg aagagtagag ttactatagg tgatgtaaat gctactttag aaaatagtat
    18961 agcaggtatg aaggtaacta agtctttttg tactgagaaa gaagagttaa ataagtttgt
    19021 aagaagcaat aaattattta gaagagcaag acaagattct tataaggtaa tggcagaata
    19081 ttactctggt atgaatttat acatggatat cttagagtgg gtagttgtaa tagctggtgg
    19141 ttattttact tatataggaa agattacttt gggtgatttt gctgcttata tactatatgt
    19201 aaaaatgttt atacaaccta tgaaaaaatt aataaacttt acagagcaat atcaaaatgg
    19261 tatgacaggt tttaaaagat tcatagagat aatggaacaa gaccatcaaa aagaagctaa
    19321 aaatcctatt gaacttgaaa atgtaaaagg tgacattgag atagaaaata tatctttcac
    19381 atatgaagat aagactcaag ttttggataa tttaagttta tctataaaag ctggtaagac
    19441 tatagcatta gttggacctt ctggaggagg aaagactaca ttatgtaatt tattgccaag
    19501 attttatgaa tttgataagg gtgatataaa aattgatgga aagagtataa aagatgttag
    19561 tttaaaatca ttgagaaaaa atataggtat agttcaacaa gatgtatttt tatttacagg
    19621 aactataaga gataatattc tttgtgggaa ccctaatgcc acagatgaag aaatgatagc
    19681 tgctgctaaa aaagctagaa tacatgactt tgtagagact ttgccagatg gatatgatac
    19741 ttatatagga gaaagaggcg taaaattatc aggtgggcaa aaacaaagaa tttcaatttc
    19801 aagaatcttt ttaaagaatc ctccaataat aatattggat gaggctacat ctgctttaga
    19861 caatgtaaca gaaagagaaa ttcaagagtc tttagaggaa ttaagtaaag atagaacaaa
    19921 tttagttgtt gcacatagat tgactactat aaaaaatgct gatgaaatca tagtattgac
    19981 ggataaagga attgaagaaa gaggtactca tgaagagcta gtaaacaaaa atggagtata
    20041 tagtaggtta cacaataact agtatacaaa ttttacacca tagctaacat acacattaaa
    20101 cttacaaaca taggatatat taagattcat aaagacaatt cattttatat ttataagatg
    20161 ttttatgaat aaaatgtatc ctatgtttta ttttttgcaa attacattta attctctttg
    20221 taagaataga gttaaatagc caatggtcgg gataacgttt ttacaaaaag aataatttag
    20281 aaaactaact ttaatttatg gaatttatcg aattttatga aaaaaatcga attttgactt
    20341 gaaatgtttt tcaaaagtag taaaataatg gataactata catacatttt ataaaaatat
    20401 atttattatg aggggggatt ttgtatggag gcaataacag ctttttgtct agttttagta
    20461 tcactgacga taggagatat agtttcagca aaaactaaag cttttgttcc gtcggttttt
    20521 gtatcagcaa ttatatttat agtaggattt tggacttttt tcccagaaaa tattgtggac
    20581 ttagccgctt taggaacacc attagctcaa ttaggtatgc ttttgttaat aactcatatg
    20641 ggaactatga tgagtattaa ggaattagca ggtcaatgga aaacaatagt aatagccttg
    20701 gcaggaatag taggaatatg tgtaggtgct ttggcattag ggacagtagt atttggatgg
    20761 gatacagcag taatagctac acctcctctt actggagggc tagttgcatc tataatgatg
    20821 gcagatgctg ctacagcaaa aggtcttgca agtttatcag tacttgcaat tttgatgtat
    20881 gttgcacaag gatttgcggg ttatcctatt acagcattaa tgcttaaaaa agaaggaaaa
    20941 agacttttat cagactttag aagtggaaaa gtaactgtaa atacagatga agaaaaagtt
    21001 aaggatttac ctgaacaaaa aagcagattt aagataatac cagacttacc agaaaaatat
    21061 gatacgacat atatgataat acttagatta ggatttgtag catggttagc agtacaattt
    21121 acaaatctta caaatgaagt tgtatcaaga tatgttatat gtttaatatt tggtgtaata
    21181 gcatcagaac ttggaatagt tgatagaaaa ccacttaata aatctggttc atttggatgg
    21241 ttaatgacat cattgatggc ttttatattt gcagggttag caaaagctac accagcaatg
    21301 cttgttgaaa tggcagttcc tcttgtagga atcataatat ttggtgtaat aggtatggga
    21361 atattctcta ttatagtagg taagctttta ggtgaaagta aagaaatggc tttttcagtt
    21421 tcgcttacat cactttatgg ttttccacca aactatatat taactgaaga ggcagtaaag
    21481 gctttggctg aaacaccaga agaaaaagaa tttttaatgg ataagatgct tccaaagatg
    21541 cttgttggag gatttactac agttacaata gcttctgtag taatagcagg tatctttgta
    21601 aatctaatat agtatttaag tgataaaaag tattttaaat aagaagaatg tgtactactt
    21661 ggaggtatgg aatggatatt aaagaaataa caaagagtta taaagactat gtaattaagc
    21721 ttagaaggga atttcatgaa aatcctgaga aaagtatgga agaagtgaga acatcaaaga
    21781 gagttaaaga agaacttgat aaaataggga taccatatgt atcagctgga ggtacaggtg
    21841 taattgcaac tataaaagga gctaatccag gaaagactgt agcacttagg ggtgatatgg
    21901 atgctctaca agttgttgaa tgcactgatg tagaatacaa atctaaaaat gaaggactta
    21961 tgcatgcttg tggtcatgat ggtcacacat caatgcttct aggggcagca aaagtgttaa
    22021 atgatattaa ggatagtatc aatggaactg taaaattatt ttttcagcca ggagaagaag
    22081 ttggtaaagg tgcaagagct atgattcaag atggtgctat ggaaggtgta gatagtgtgt
    22141 ttggaataca tctttggact gatgtagaat ctgggaccat atcggtagaa gaaggaccaa
    22201 gaatggcttc tgctgatttc tttaaaatta ctgtaaaagg tagaggtggt catggttcac
    22261 ttcctcatca aggtgttgat gcagtgcttg caagttcagc aatagttatg aatctacaat
    22321 ctatggttag tagagaagta agtcctctgg aaccattagt tgtgagtgtt ggagttttaa
    22381 attctggaac tagatttaac gtaattgcga gtgaagctgt cttagaaggt acaataaggc
    22441 tatttaatcc agagcttaga aagcaaattc ctggaatttt agaacgtata gcaaaatcta
    22501 cagcagaagc atatagagca gatgctgaat tagagtatgg gtacttaaca ccagcagtta
    22561 taaatgacaa agaatgttca aagatagcta cagatgcagc aattaagcta tttggagaag
    22621 actgtataac actatttgaa aaagtaacag gagcagaaga tttagctgag tttatgaata
    22681 tagcacctgg tgcactagca tttgtaggag ctagaaatga gtcaaaaggt gcttgttatc
    22741 ctcatcatca tggatgcttt aatatagatg aagatgctct agaaattgga actgctttat
    22801 atgtgcaata tgcagtggat ttcttaaata aataatttta atatactata aagaaaaagc
    22861 agagactaag tttatatctc tgctttttta ttgtgtatat tttttataaa tattgactat
    22921 ataaaatata tatgatagca taaagaaaat gataatcaat atcaattaaa aagaaggtga
    22981 tttatttgaa taatgtaata tttgcatttt tgataacatt attggctggt ttatctactg
    23041 gtataggaag ttgtatagca ttttttgcta aaaaaacaaa tactaagttt ctttctataa
    23101 gcttaggatt ttctgctggt gttatgattt atgtttctat gatagaaatt tttcctaaag
    23161 cacaagatgc tttgacaaaa tctatgggag agaaattagg aagttggtca actgtaatag
    23221 ctttttttat aggtatggct atcattgctg ttattgataa gctaattcca caagaagaaa
    23281 atccacatga aataaagaaa atggagaata tagaagaaaa gaatatcaaa aaaaataagt
    23341 ctcttttgag aacaggtata tttacagcaa tggctatagc aattcacaat tttcctgaag
    23401 gattagctac atttatatca gctcttgatg atgttacaat agctattccg atagcaattg
    23461 caattgcaat acacaatata ccagaaggta tatctgtatc tgtaccagtt tattatgcca
    23521 caggagataa aaagaaagct ttttattatt cctttttatc tggtatgtct gagcctttag
    23581 gagcgattat tggatatgta cttcttagaa attttttaaa tgatataact cttggaattg
    23641 tatttgcaat tgtaggagga attatggtat tcatatcact agatgaatta ttgccatcag
    23701 ctagagagta cggggaacat catttatcta tttatggatt gattgcagga atgggtgtta
    23761 tggctattag tttattacta tttaaatagc tttttaaata tatgattgta acctaaaatt
    23821 agtatcaaaa tgatataatt atttaaatag atttttaagc tatttaaaaa tatcattttg
    23881 gagaatgagt gctatggaaa agaaaataaa attcaaattt gactggtata gttcacctga
    23941 taagatagag aaatggttag aagatattga agctaaagga tataatttat ataagataaa
    24001 taaatttgga ggaatatttt attttcataa gggaagtcca agaaaaataa aatacactgt
    24061 tgattactac tatgatgtag agaataatta ttttgatgaa cataaatcaa atggctggaa
    24121 tcttgtattt aggagtattg gtagttttat gggtacatct gcatggtata tatggtcgaa
    24181 agaatacaaa gacatacctc ctaaattata tagtgattct gataaaaaaa acaaagtaaa
    24241 gtcaatttta tttatgaata tgtttatatt ctttatgtta gtagtaatat ttatatattt
    24301 attgaatatt gaaataagaa atttatatag tggttatgga gcatctgtaa ctgctattgt
    24361 actacagatt atattgttga ttttatatgc agtacaatta tataggagat taatgtatta
    24421 tttaaggctt aaaaagttta aataaataaa agaaggtgtc ctaaaattat ttttttaata
    24481 gtttaagaca tcttctttta tcagtaagta ctgtttttaa ttatagtaat ttctgtcttt
    24541 aaattgaaat atcaaataat agttatatgg gattgagtat tgataaaaat aatttgaaaa
    24601 tgttatccta aagtatcaga tatacaaaat tatctttaaa tatattataa atattttaat
    24661 tgtattaact agaaattatg taaggaggca ttttatgatt aagatagcag tttgtgaaga
    24721 tgaaaaagaa acacaacttt taatagaaga ttaccttgag aatatattaa aagatataag
    24781 tatagaatat gagatacaaa agtatatatc tggagaagag ttactggaaa gtaatttaaa
    24841 agatatagat atattacttc ttgatataaa aatggaaaaa ttaaatggaa tggatactgc
    24901 aagaaagatt agagaagtag acaatgaaat ggaaataata tttgtaactt cattaataga
    24961 ttatgtgcaa gaaggttatg aggtaagagc ttataggtat ttactaaagc caatagagtt
    25021 ggaagaacta aaaaaacatg tgctaacttg tatcaaagat attgaaataa ataaggaaag
    25081 tcatattaca ataaaaaata agtctaatac atataagatt tatttaaatg aaataaaata
    25141 tatagaagtt caaaaaaaag atatgctaat acacacaata aacaagaatt ttgatataaa
    25201 atatagttta ggcaaaatag aaaaagaatt aaatccatat aaatttataa gatgccataa
    25261 aagttttata gtaaatttaa gatatgttga aaatataaag cctaatactg caatactgga
    25321 aagtggagaa gaggtaccta ttagtagata tagatataaa gaagttaagg agaaattctt
    25381 aaaatttctt ggtgatacaa tatgctaaac tttatgactg agctattagt agttttatct
    25441 atatttatac agttttctat aatgaacgga attttaattt ataaaaagga tagtaaaaaa
    25501 aatgaaaaaa tagt
//
LOCUS       DAEPHU010000064        23386 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 01A10CD0081
            SAMN05941466-rid12468953.denovo.064, whole genome shotgun sequence.
ACCESSION   DAEPHU010000064 DAEPHU010000000
VERSION     DAEPHU010000064.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941466
            Sequence Read Archive: SRR6291087
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 23386)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23386)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068158.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 22:43:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,892
            CDSs (total)                      :: 3,805
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 87
            rRNAs                             :: 8, 1, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 55
            CDSs (without protein)            :: 55
            Pseudo Genes (ambiguous residues) :: 0 of 55
            Pseudo Genes (frameshifted)       :: 21 of 55
            Pseudo Genes (incomplete)         :: 28 of 55
            Pseudo Genes (internal stop)      :: 16 of 55
            Pseudo Genes (multiple problems)  :: 8 of 55
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23386
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941466-rid12468953.denovo.064"
                     /strain="01A10CD0081"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            436..906
                     /locus_tag="KR231_002722"
     CDS             436..906
                     /locus_tag="KR231_002722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glyoxalase/bleomycin resistance/dioxygenase
                     family protein"
                     /protein_id="HBH0005085.1"
                     /translation="MKYQVSLLAVKDIEVSKKFYKELFEQEIELDLGKNVTFKGGFAI
                     QEDFAWLTGINPDTIIQKSNNMELYFEVDDFDEFIEKLNYYKDVEFVHKPLKHEWQQR
                     VVRIYDPDKHIIEIGESMEVIARRYLSEGYSVEETSKIIQHPIKFVKQCENSKE"
     gene            1210..2079
                     /locus_tag="KR231_002723"
     CDS             1210..2079
                     /locus_tag="KR231_002723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Nif3-like dinuclear metal center hexameric
                     protein"
                     /protein_id="HBH0005086.1"
                     /translation="MVIIKAIELYKKLDLEFNIKNINDDWSFMNFENDFITPEFRKKY
                     IGLVLDNAQNINKVYTTTFPDKEIIKQVIDKDEKDILIFSHHAMGYIASDEGFPFHDI
                     PLSYMEEMKNRRISFYVLHSPLDNYSDYSTSVSFAKAMGLEIVKPFCKYDDKIEVGVI
                     CKTSLKSIEEIKELIKKSVGHDVKLYDYGDSVLKDGLVAIAAGGGSYPFVAREVAELG
                     INLYITGFTKPLKHFEPVLEFHQIAKDNLINVIGATHYSTEKFACMGMVDYFKNLGLE
                     SEFLQGKYYLEDL"
     gene            2954..3661
                     /locus_tag="KR231_002724"
     CDS             2954..3661
                     /locus_tag="KR231_002724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HBH0005087.1"
                     /translation="MIFTKSNKYDKDFLMKNMMGPNCIKILEELTSKIKLEKGMRILD
                     LGCGKGISSIFLAKEFDATVFATDLWIEPTENYKRFKEFKLDDKIFPIQAEAHELPYA
                     EGFFDAVISIDSYHYFGNKEGFLDNHISPLVKEGGILAMAMPGLKEDFVDCIPDELIP
                     FWQDNMNFHSITWWNKLWSESESVIVEKCEALNCHDEAWKDWINCDNSYAINDKKMME
                     VENGKYFNTISLIARTK"
     gene            4260..4760
                     /locus_tag="KR231_002725"
     CDS             4260..4760
                     /locus_tag="KR231_002725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBH0005088.1"
                     /translation="MIEGIKFIKAEEKYIYSYWQTFDKIAKERKYLAMDEAFPFEETV
                     EFIKNIINKNLPQLFIIDLESDNCIGWCDVLPKTEKVGYLGMGILKEYREKGIGSNLL
                     KQIIDLSKEYGYEKIELDVFKSNSRAIHVYKSLGFVEVNTISSGFTWNDRPVKEEVIQ
                     MELTLI"
     gene            complement(5010..5789)
                     /locus_tag="KR231_002726"
     CDS             complement(5010..5789)
                     /locus_tag="KR231_002726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0005089.1"
                     /translation="MNKNILNNSFPEVPESFHNSLSKTLNSLPEREENYKMINNKTHK
                     LPFRKGLVATLAITLILSTTALAVGHIYSLVGKSSTKATYTSIPTTEQVKKDFNFTPN
                     IVSEFSNGYKFKGAYTVNKKAFDKENNVLGKSKALSFEYKNGNDEISLDTANNVLGKS
                     SDNLKVVDTYKDINISYEAFAQKFVPEGYKMTEQDKIDEKSGKYTFSVGPNNESDKVE
                     VNKFKFLTWKQDGVYYSFTVQDSNLSMNDLVKMAHEVIDAK"
     gene            complement(5786..6265)
                     /locus_tag="KR231_002727"
     CDS             complement(5786..6265)
                     /locus_tag="KR231_002727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HBH0005090.1"
                     /translation="MDKTTFTNNILESEQTLYRVSKSILGNDQDCEDAVNNAILKAYE
                     KLDSLKEEQYFKTWLIRIVINECNSLRRKRLKSLSFEDVFKNKKIDEKDDYSDLYTAI
                     QSLPKKIKIPIVLYYIEGYSVDEVKEILDIPQGTVKSRLSRGRRLLKTKLENTEVII"
     gene            6764..7054
                     /locus_tag="KR231_002728"
                     /pseudo
     CDS             6764..7054
                     /locus_tag="KR231_002728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426892.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            7251..8258
                     /locus_tag="KR231_002729"
     CDS             7251..8258
                     /locus_tag="KR231_002729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nuclear transport factor 2 family protein"
                     /protein_id="HBH0005091.1"
                     /translation="MGKYQDSKKVVRNYFEALENATGDEVENVLKQHMKSDYNWKGVY
                     PFREQEGTENVADVFWKPLKKSLSNMQRRQDIFIAGTNEIDNSEWVMSMGHFMGLFDN
                     DWLGIKHTRKMISLRYAEFNCVQDGKIAKTGLFVDIIGFMIQAGVNPLPPQTGSYFVY
                     PGPIDHNGLLFEDADEVEGVKTLALVNKMVDDLSELNESGAMGCPPEILEKSWAKDMI
                     WYGPGGIGASYTIPRYQEQHQLPFRNNLKGKTFNGHVCRFAEGNFACFFGWPNLTNVP
                     CGGFLGLPGGEVKADMQVVDVYYRKGDKLQENWVLIDIPYWLKQQGLDILERTKSIFN
                     A"
     gene            8296..9723
                     /locus_tag="KR231_002730"
     CDS             8296..9723
                     /locus_tag="KR231_002730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895719.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ester cyclase"
                     /protein_id="HBH0005092.1"
                     /translation="MASTNKNNATSKEEEKEVSTSGLESCTVKENKAKMNQTNFSNIN
                     ENQTNENKTNTYKRNIDKGNIDKGNIDKTNTNKSDINKVNIDTVDTDKLNTNTLTKKN
                     KKVIFKGEDNMSSTKIYYGDSLEVTPVGVMDYNDFSKQTKREQEIPGFDSKYRDFVDY
                     IMKITHNIWEEKGIGVIYDTYHNNVTMHCGSSNLVGIKDVISNTLQTLHAFPDRRLIG
                     QNVIWSNFGADGFLSSHRVLSTATNLGDSNFGPATGRKINFRTVIDCATTNNRIHEEW
                     LVRDNLWIVTQLGLNPQEVAKSMAKASESKVLSLQSTYGICESMDGQFMPTKYQAKDD
                     SAGEMMLEMTSRIYNYKYINEVKKYYHDNAVVHFICDKDLNGYDEIQGMIVSLLASIP
                     NGSYEVERVTCNQREKNEGYDVSVRWRLRGINEGIGFFGQPSGKHIEVMGINHYHILQ
                     GKVKEEWITFDGMDVLKQMYMGVEE"
     gene            9865..11130
                     /locus_tag="KR231_002731"
     CDS             9865..11130
                     /locus_tag="KR231_002731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBH0005093.1"
                     /translation="MKTTVEIENDIILGKDYSNLKRGIAFFSIALIYFFYCYNFMVGT
                     FIKPTMIYALADGGFGFSLKQTEEIFAVMSFGTIPGTFIFGVISTKIGKKRTLISVAL
                     LIGLTTFIPMLSPTNIMLWKIARLCTGVVLGGVFGTAMPLVADMFPSKYRGKLAAILT
                     ALFSLAMIFGGKVYGVLGDANWQILMYTAIIPPIVGAILAIFFVPDDLEYTKELVKKG
                     KETGEKISYISMYKGKYLWIGLGTILLSGANFTAYSAFSNNATTYLVTRIGMSAAVAG
                     SIYSLQGIGQLVGYLFWGSIADKFGRKIPFIGMALAAVFVFIYTKLGGDNTTTFYMIS
                     VLLGVAVGYSGAWGAYYTELFPSKYRSLSSGMSFNGGRIISTFAIPAIAGTASGTLGM
                     MTIFYISIAVFVAGAIVWLFLPETLNNKK"
     gene            11172..12770
                     /locus_tag="KR231_002732"
     CDS             11172..12770
                     /locus_tag="KR231_002732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:solute symporter"
                     /protein_id="HBH0005094.1"
                     /translation="MISSIDVCIIIGYLLLMLVIGYYSGKDNKNQEDYFLAGRSMPWI
                     PIALSVAATMISANGFIGGPGWAYVDGMYPVMVNITVPLAIFFALSITTPVIYKLKIT
                     SIYEYMGLRLGNYSRGLTIIQFFINSLIQASSMVYIPVLIIQMITGWSLYALVPIVVL
                     VSIIYTLLGGIKAVIWTDSIQMIVVISAVFIVIIVALKGMNLSFFDTLQIAQQSGKLN
                     TFDFSRDISVTNTFWATLIGGTVMWIRYFCFDQSQVQRVLTSKSLKCAKNSFVVSAFV
                     MNLVYYFMLLVGVILFVFYGGRTFETSNEIMITFILNELPVGAIGIIIAGVFAAAMSS
                     IDSILNSMTTVFTKDIYEFYFKKDNKESSLKVTMIITVVIGVVMTGFIIMGFGGSIKS
                     ILDLVGNYISYFAGPATGAFVLAMFTYKANDKGVSIGFIVGLVLGFFISNKYNVSWLW
                     NPAIGATITLIFGYIFSVILKKNHNADDIKKYTAFGMRNHLISQGMDKVDGVSIVPFS
                     LGKQELIVLAFFIIQYIILFLIQF"
     gene            12805..13827
                     /locus_tag="KR231_002733"
     CDS             12805..13827
                     /locus_tag="KR231_002733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HBH0005095.1"
                     /translation="MNQKKVHYNKSATSKDVARLAGVSQSSVSRAFGSANGKGVKPEV
                     RERIFRVANEIGYVPNLVARGMISGKTNVIGLIVGDSLGPFYNRIINLFVEKIQEIGK
                     QCLVFKVPRQQSIDSIISKVIQFQVEAVIITASAMNKVMAETCEENNIPVILFNRFIP
                     GIKISTVYVDPIEGGGMAAEYLLKKGHKNIGYIQFTRETSEEMEKKIGFYSKLRQSGI
                     HNLKEESANYDYDSGYEAGKRMLALSNPPTAIFCTSDLIAIGVMDAARFEYKLRVPED
                     LSVIGYDDIQMASWKSYNLTTIRQPLDLLIEKTINILKSLLNEENPESVVEMLKPELI
                     ERGSTL"
     gene            complement(14215..15618)
                     /locus_tag="KR231_002734"
     CDS             complement(14215..15618)
                     /locus_tag="KR231_002734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HBH0005096.1"
                     /translation="MKMLNNFFKKINNPAPVFAQTKMERDNQTDDSLSTKPKTTFRDV
                     AGLDEVKEELFEIVDFMKSPQKYQKMGAKIPKGVLFYGPPGTGKTLLASAVAGETNSS
                     FFNVTGSEFVEKYVGVGAKRVRTLFEKARKEAPSIIFIDEIDAVGAKRHLESNNEKDQ
                     TLNQLLVEMDGFNKDSNVLIIGATNRLDLLDEALLRPGRFDRHIHIGAPNYHTRFEIL
                     KVHTDDKPIDKSVNLELLAKKTHGFNGAHLSNIANEAAIFAVRDDSECITSEHFDKAL
                     ERVIAGLESKNSALVEKEKKIVAYHEAGHALVSDIVGICPIQKISIVPRGQALGYVLQ
                     LPDEDRYIYTKDELIGKIKILLAGKASEELIFNHKSTGAKDDLKKVTEIANQMVCEYG
                     MSNLGFMTIDGNDKTFLCDKVQKEANRIVEICYKETLEMLKDNLEDLHSVSKFLFEKE
                     TMTHEELKDLIGKEAVN"
     gene            16485..16994
                     /locus_tag="KR231_002735"
     CDS             16485..16994
                     /locus_tag="KR231_002735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009528606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-3"
                     /protein_id="HBH0005097.1"
                     /translation="MSKELAINEQIKDKEIRVLSPTGEQLGVMPTKEAQAMANSKNLD
                     LVQISPNANPPVCKIMDYGKFRYEQARKEKEAKKKQKTIVVKEVRLRPGIEQNDLNTK
                     ANNAIKFLKKGDKVKVELRFRGRELGHKDIGKEVMLKFLDIIKEFGEPTKAPAFEGNN
                     MVVIIDPKK"
     gene            17022..17216
                     /gene="rpmI"
                     /locus_tag="KR231_002736"
     CDS             17022..17216
                     /gene="rpmI"
                     /locus_tag="KR231_002736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011721840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L35"
                     /protein_id="HBH0005098.1"
                     /translation="MPKMKTHRGAAKRLKKTGTGKLKRAKAFKKHILTKKSAKTKMNL
                     RKSTLVSDGDAKRIAQLLPY"
     gene            17272..17628
                     /gene="rplT"
                     /locus_tag="KR231_002737"
     CDS             17272..17628
                     /gene="rplT"
                     /locus_tag="KR231_002737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L20"
                     /protein_id="HBH0005099.1"
                     /translation="MARVKKAMNARKKHKKILKLAKGFRGSRSKLYRPANTFVMKALK
                     NAYIGRKLKKRDFRKLWIQRINAAARMNGISYSRLMNGLKLSGIEVNRKMLSEMAIQD
                     PEGFAKLAEVAKAKLA"
     gene            17938..18483
                     /locus_tag="KR231_002738"
     CDS             17938..18483
                     /locus_tag="KR231_002738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0005100.1"
                     /translation="MNEKLMDCFVNPIKCKLLIEIFSNNRTTAKQLGEKFQDISKATL
                     YRYLNKMLKDDIIKVVEENKIRGTVEKVYAMKLDIADDVNKIIDENSGEEYAQLFTQY
                     MMGFLREFYEYAERKEKDILKDGSGFSVCPVYASIDEIVEVSKKIASILEPLRNNSHE
                     EGRRMHSIGVIITPPKEDEGK"
     gene            18470..18634
                     /locus_tag="KR231_002739"
     CDS             18470..18634
                     /locus_tag="KR231_002739"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0005101.1"
                     /translation="MKGNKSDLHEVEPIYTENRFMIYICIQSKVSLLGLYFIVSFHLS
                     NDLEWYNEVF"
     gene            18923..20848
                     /locus_tag="KR231_002740"
     CDS             18923..20848
                     /locus_tag="KR231_002740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HBH0005102.1"
                     /translation="MKIKFVIMPLVIFLMVLFVGCQSTKDTEVKAKYTEIKILGTGDL
                     HSILTDSMVSYVNEEREKNKNLLMVDAGDFYGTQSREMWEWSSGKKLINIKRNGRAEY
                     DDIIKSSKDEVPIVKDMAKLKYDAVVLGDNEFVSNDKQSLDKLVSDFKNNNMPLVSAN
                     IYEQSGENYVQPYVMKNIKTDEGNVKVGILGLTIKEVGETLGLEDFEKDKKARELGEQ
                     ADYKGKLYANDLVEDAKKWIKVMEKESPDIIVAVVHSGEEPKTDRNPGNRIKELATTV
                     DGIDAIVAGHTHEKIDEHKYKNKSGDEVIVTQPGWHGDRVSEINFKLNKENGKWDIKE
                     KSSKLKIIDKEVSIVATADLHSHFSDKLTVDLVNERSNPIEPVVVDAGDFLDPQTDEM
                     TQWYKEWKSIRDNNSDKTISRCPMVMDMNQGMYDAVVLGNHEFVSEKDEFWSDERLLD
                     AVIEDFEQVAISVLSANIYRQSGKNYVKPYIIKDVETSEGNVKVGILGLTIKEVGKGL
                     KNVNLQEQFQYKDKLYANDLVEDAKKWVKVMKKKKPDIIVAVVHSGEEPKNPKHPGNR
                     IKELATTVDGIDAIVASHTHEKIDEHEYKNKSGEKVIVTQPGEHGKYYSKITFKVNKE
                     KGSWIINDKFSKTIEVE"
     gene            21249..23153
                     /locus_tag="KR231_002741"
     CDS             21249..23153
                     /locus_tag="KR231_002741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HBH0005103.1"
                     /translation="MKIKFIIVASIIFLIVLLVGCQSTKDTEINVLATSDLHSIIPDN
                     LISYVEEERKYDENLLMVDAGDFFDMQSGEMNKWFTGQKLVRFKDGIPEYKKIAEPRE
                     GEVPLAKKMAKLKYDAVTFGNHEFVSNDKQSLDKLVSDFKNNNIPLVSANVYEQSGEN
                     YVKPYVMKNINTDKGTVKVGILGLTIKEVGERSRFKSFEQDKKARELGEQPQYKGKLY
                     ANDLVEDANKWVKVMEKKEKPDIIVAIVHSGEEPKNPKNPGNRIKELATTVEGIDAIV
                     AGHTHEKIEQHTYKNNSGEEVIVTQPGAHGNSISKINFKLDKKNDKWFIKDKYSELKI
                     FGKEVNIITTSSLNPKFSDEMAVNLFNERDRDVQPIFIDTGDFLNTNTKEMTKWAKEW
                     QYNENKGIYKKINEWPIVYLGYDAVVLGSHEFTEDKETFEEKKSTLDYIIENFEEMKI
                     PVLSANIYDESGENYVKPYIIHNVETREGNIKVGVLGLTTTDKDEEDLSSSSLSKDSK
                     TSKIPEETGKLYTNNLVKDASEWVKVMQKESPDVIVAVVHSDNNSTLKNPSSEVKKLA
                     MSVDGIDAIVVGHTKNKVEEHIYKNKSGDEVIVTQSGEDCYSKISLELRKENGKWNII
                     NKYSKAIKMK"
BASE COUNT         9050 a         2493 c         4059 g         7784 t
ORIGIN      
        1 tgacacagtg ttttcgtatt taagatgata aaataaatag gaattaatga tgatattgaa
       61 aaaataaaaa taaaggatta atataagata ttaaagagat agagataaaa gtgttaacag
      121 aagatattga aaaaataaaa gattgatata agatactgaa gaggtagaaa caaaagtatt
      181 aatagaagat attgaaaaaa taaaaacaaa agattgatag aaagtactga atagatagag
      241 ataaaagtgt taatagaaga tattgaaaaa ataaaagatt gatataagat actgaagagg
      301 tagaaacaaa agtgttaata gaagatacta aaaaagtaaa aataaaggat taataaaagg
      361 tactgaagag atagagaaaa aaatgttaat agaagatact gaaaaaatag aaataaaaaa
      421 ttaggaggaa aatttatgaa atatcaggtt tcattattag cagtgaagga tattgaagta
      481 tcaaaaaaat tttacaaaga attatttgag caagaaattg aattggactt aggtaaaaat
      541 gtaacattta aaggaggatt tgctatacaa gaagacttcg catggcttac agggattaat
      601 ccagatacaa ttatacaaaa atcaaataat atggaacttt attttgaggt tgatgatttt
      661 gacgaattta ttgaaaaact caattattat aaagatgtag agtttgtcca taagccacta
      721 aaacatgaat ggcaacaaag agtagtgcgt atttatgacc cggataagca tattattgag
      781 ataggagagt ctatggaagt tatagctaga agatatttat ctgagggata ctctgtagaa
      841 gaaacttcta aaataattca acatccaatt aaatttgtaa agcagtgtga aaatagtaag
      901 gaatgattgt ttaaattata attatttagt agaaattaat tgtaatagaa ctaattcaag
      961 ataatatata ggactagtat ttgacaaatg tcataaatta aattaaaata aagaaaatat
     1021 taataaagaa aaaataaata aaaataaggg gaatattaat aaagaaaaaa taaatataat
     1081 attaaaatat attaataaat ttgaatattt ataatatttt taatttgaag taggaatact
     1141 taaacgtata aagtttatta tcggaaattt ctatattaat atgtagtaat tcaatattat
     1201 tataaaggag tggttattat taaggcaatt gaactttata aaaaattaga tttagaattt
     1261 aatattaaaa atattaatga tgattggagt tttatgaatt ttgaaaatga ttttattact
     1321 ccagaattta gaaaaaaata cataggatta gtattagata atgctcaaaa tattaataaa
     1381 gtatacacaa ctacttttcc tgataaagaa ataattaagc aagttataga taaagatgaa
     1441 aaagatattt taattttttc acatcatgca atgggataca tagcatcaga tgaaggtttt
     1501 ccatttcacg acataccact atcttatatg gaagagatga aaaatcgtag aatttctttt
     1561 tatgtattac attctccact agacaactat agtgactatt caacttctgt tagttttgca
     1621 aaagctatgg gtttagaaat agtcaaacca ttttgtaaat atgacgataa aattgaagta
     1681 ggagttatat gtaaaacatc actaaaatca atagaagaga ttaaggaatt aattaaaaaa
     1741 tctgttggtc atgatgtgaa attgtatgat tatggagatt ctgtattaaa agatggttta
     1801 gttgctattg cagcaggggg aggaagttat ccatttgtag caagagaagt tgctgaactt
     1861 ggtataaatc tatatattac tgggtttact aagcctttaa aacattttga accagtatta
     1921 gagttccatc aaatagcaaa agataattta attaatgtta taggtgctac tcattattct
     1981 acagaaaaat ttgcgtgtat gggcatggtc gattatttta aaaatctagg tttagaatca
     2041 gaatttttgc aaggaaagta ttacttagag gatttatagg acatattaaa caataaaaat
     2101 aaacagttag taaaaattta ttttactaac tgtttatttt tttacctatt tatccagtgt
     2161 tttgaaaaaa tctatcttta ttttttaaac taagaaaata gacttttaat tgctgattag
     2221 aagatttagt tttgatgtct tttaaattat ttttcgatat tttttagttt attttttgat
     2281 gtattttaga ttattattta ggattgatta gaatttataa atatttattt tagattatta
     2341 taaatattta ttttaaaaaa atagaattat tatatttatg ataataaatg gtataataaa
     2401 aggtaaagtg tcaaatatgc actaaattaa ataagttaat tagtatatag gttaaagtgg
     2461 aagtaattaa aacttattaa gtattagaaa atgacttctt attagagtaa gtatctaaaa
     2521 tgatataaaa attatgatta ctcattaaag tgactattat agagtggata agattactca
     2581 ttaaagcgat tactgtggag tagataaaat tactcactaa aataactatc atagagtgga
     2641 taagattact cattaaagcg attactgtag agtagataaa attactcact aaaataatta
     2701 tcatagagtg gataagatta ctcattaaag cgattgctgt ggagtagata aaattactca
     2761 ctaaaataac tatcacagta gataagatta ttcattaaag ttactatcac agagtggata
     2821 aaattacaca ttaaaattgt ctgttaaaga atgaataaaa aagagattgc tcaatataag
     2881 aagcatataa aaaataaaaa atcaaacgta taaaatttaa taaataataa ctgataggga
     2941 aaggaaagat agaatgatat ttacaaaaag taataaatac gataaggact ttctcatgaa
     3001 aaatatgatg ggacctaatt gtataaaaat attggaagaa ttaacaagta agataaaact
     3061 agaaaaggga atgcgtattt tagacttagg ttgtggtaaa ggtatatctt cgatattttt
     3121 agcaaaggaa tttgatgcta ctgtatttgc aacagattta tggatagaac caactgaaaa
     3181 ctataaaaga tttaaagagt ttaaattgga tgataaaata tttccaatac aggcagaggc
     3241 acatgaacta ccttatgcag aaggtttctt tgatgcggtg ataagtatcg attcttatca
     3301 ctattttgga aacaaagaag gatttttaga caatcatata tcacctcttg taaaagaggg
     3361 gggaatactt gctatggcaa tgcctggatt aaaagaagat ttcgtggatt gtataccaga
     3421 tgaactcatt ccattttggc aagataatat gaacttccat tcaattacat ggtggaataa
     3481 actttggtct gaatcggagt ctgtgattgt agagaaatgt gaagctttaa attgtcatga
     3541 tgaagcttgg aaggattgga taaattgtga taattcatat gctataaatg acaaaaaaat
     3601 gatggaagta gagaatggaa agtattttaa tacaatttct ttgatagcga gaactaaata
     3661 attgtgatga atttataaaa gtataagata agtagaaata taagttgaat gagagtataa
     3721 gaagcataga aatataagtt gaattaaagt agaaggtaaa taaaaatgta agttaaataa
     3781 agagtttata caaaaatgat tttttagatt atttataccc aatcgagttg cttaggtcag
     3841 ttgggtattt ttatttttta aagttaaatt gcaaatacta ttgtgtgata tatattttaa
     3901 tactaaatgt ttgttttata agaaataaac taatagaaaa aatagtttta acaatgaaag
     3961 caaaaaaggt attgatgaag attaaaaatt ttatagtacc attttatata ttttattata
     4021 ctttaaatca aatttcaaaa tgattaagta tatataccca aaagattaaa gaactatatt
     4081 tattatacta ttaaaaatta ttttaataga gatacaagag atagatatat tggttttaat
     4141 tttatagaaa tatacaaaga tattttaagc taatatatag taatttatat agcattataa
     4201 aatagaatca tataaaataa gttaactaca atcaaaaatt aaaaagggga aatgttaagt
     4261 tgatagaagg cataaaattt ataaaggcag aagaaaagta tatttattcg tattggcaaa
     4321 cttttgataa aatagcaaaa gagaggaaat atctagctat ggatgaagcc tttccttttg
     4381 aagaaacagt tgaatttata aaaaatatta taaataaaaa cttaccacaa ctgtttataa
     4441 ttgatttaga atcagataac tgtattggtt ggtgtgacgt tttacctaaa actgaaaaag
     4501 ttggttattt aggcatgggt attcttaaag agtataggga aaaaggtatc ggaagtaatc
     4561 ttttaaaaca aattattgat ttatcaaaag aatatgggta tgaaaaaatt gagcttgatg
     4621 tatttaaaag taatagtaga gctattcatg tttataaatc tttagggttt gtagaggtaa
     4681 atacaatatc tagtggtttt acatggaatg atagacctgt aaaagaagaa gtaattcaaa
     4741 tggagcttac acttatataa aataaagtta aagtctttaa aattccatat acacttgtat
     4801 aaaataaagt taaagccctt aaaattccat ataaaagaaa tatttttaag ggctttttaa
     4861 taatgcttct tttgaaggta gctaaatatc taaaatttta tatattaaat ttaaagaaaa
     4921 tataaagatg gaagatacaa ccatgtttac taataaaaaa attaaagtca taaataataa
     4981 actcataaac aacttattat tacttatgtt tattttgcat ctattacttc atgagccatt
     5041 ttaactaagt cattcataga taaatttgag tcttgaactg taaaagaata gtaaactcca
     5101 tcttgtttcc atgtcaaaaa cttaaattta ttaacttcaa ctttgtctga ttcattattt
     5161 ggccctacac taaatgtgta tttgcctgat ttttcatcaa ttttatcctg ttctgtcatt
     5221 ttataacctt ctggtacaaa cttttgtgcg aatgcttcat aagaaatatt aatatctttg
     5281 taagtatcta caacttttag attgtcagaa ctcttcccaa gtacattatt tgctgtgtca
     5341 agagatattt catcattgcc atttttatat tcaaaactaa gtgcttttga ttttcctaaa
     5401 acattatttt ctttgtcaaa tgctttttta tttacagtat atgctccttt aaatttatat
     5461 ccattactaa attcagaaac tatattaggg gtaaagttaa agtctttttt tacttgttct
     5521 gtagttggga tagatgtata ggtagcctta gtacttgatt ttccaaccaa actatatata
     5581 tgtcctactg caagggctgt tgtgctcaat atcaaagtaa tggctaaagt tgcaactaag
     5641 ccttttctaa atggtaattt gtgtgtttta ttattaatca ttttataatt ttcctctctt
     5701 tctggtaaac tatttagtgt tttgcttaaa ctattatgaa aactttctgg aacttctgga
     5761 aacgaattat ttaatatatt tttattcata tgattacctc cgtgttttct aatttagttt
     5821 ttaataatct tcttcctctt gataatctac tttttacagt tccttgaggt atatctaata
     5881 tttccttaac ttcatctact gaataacctt caatatagta aaggactatt ggaattttaa
     5941 tttttttagg tagactttga atagcagtat acaaatcgct atagtcatct ttttcatcaa
     6001 tttttttgtt tttgaagaca tcttcaaatg atagagattt taatcgtttg cgtcttaatg
     6061 aattacattc atttatgact attctaatca gccatgtttt aaagtattgt tcttccttaa
     6121 gagaatccaa cttttcatat gcttttaaaa tagcattgtt gacggcatct tcacagtctt
     6181 ggtcgtttcc tagaatagac ttagatactc gatacaaagt ctgttctgat tcaagtatat
     6241 tgtttgtaaa tgtagtttta tccaactaag ttccttccct tctatgcaaa tcgtagcgct
     6301 acttttttgt ctttcactta ttagataaaa ttttactata gatggttcac tttttttatg
     6361 attatttgat aaatttaagt ttgaaagttt tgcctattct atacaaatat tctataatat
     6421 attttttcta gtattttccc ctcatatata aagccatgta gatatattaa actttagaag
     6481 ccatttatat atttagtttt atagtaagtc tttatattga gtaattagaa aatagtaagt
     6541 atttaatgtt gagtagttag aataacaatg cttttggatt atttacttca tgtacagatt
     6601 taaaataagt tctttaaata gcaacttttt gaaaaaacgc aaaaatattt tatgttgtct
     6661 gattatattt atagatgtga aacaatattg tatagagtaa aagtatatag aagatgatta
     6721 catagagttt atacttgaat tttacaaata taattatcaa aatactgtca aagagaaaaa
     6781 tagttttgat gaacgttttt atcaaattgc tacagagaca gggctaagtg ctaatactgt
     6841 atataaagta ttcaataaaa taataaatag tggaaaaact gaatttacat caaaggaatt
     6901 agctactata tgtggtgtaa gtattagaac tatggacagg attatactta gattgtgtga
     6961 ttctggttat tgtgaggtag tgagtgaaca gcttatgagc aagtatggta gacccagtag
     7021 aatattacgt tttaaacctt ttctgttgtt ttaaatagat ataagtcaaa aattaaattt
     7081 ttatgataac attttcttta caatttttta gatatatgtt aatatttaga aaaatgcata
     7141 tgtattcata aaataaactt aaaacagcta aaaaatcatt aaaaaggaaa ttgtatgcat
     7201 gaaatgagaa agttaattta taacttaaat aaatctggga ggagataatt atgggaaaat
     7261 atcaggattc aaaaaaagtt gtaagaaatt attttgaagc attagaaaat gctactgggg
     7321 atgaggttga aaatgtctta aagcaacata tgaaatcaga ttataactgg aaaggtgtgt
     7381 atccatttcg tgaacaagaa ggcactgaaa atgtagcaga tgtattttgg aagcctttaa
     7441 aaaaatcatt gagtaatatg caaagacgac aagatatttt cattgcagga acaaatgaga
     7501 ttgacaatag tgaatgggta atgagtatgg ggcattttat gggacttttt gataacgatt
     7561 ggcttggcat taaacatact cgtaaaatga ttagtttaag atatgcagaa tttaactgtg
     7621 ttcaagatgg taaaattgct aaaactggat tatttgtaga tataattggg tttatgattc
     7681 aagcaggagt taatccattg ccaccacaaa caggttcata ttttgtatat ccagggccaa
     7741 ttgaccataa tggattactt tttgaagatg cagatgaagt tgaaggagta aaaactttag
     7801 cattagtaaa taaaatggta gatgatttat ctgaattaaa tgaaagtggt gctatgggat
     7861 gcccaccaga aatacttgaa aaatcttggg ctaaagatat gatttggtat ggtccaggtg
     7921 gaattggtgc ttcttatact atacctagat atcaagagca acaccagcta ccatttagaa
     7981 ataatttaaa aggaaagact ttcaatgggc atgtatgtag atttgcagaa ggtaattttg
     8041 cttgtttctt tggatggcct aatctgacta atgtaccatg tggaggtttt ttaggattac
     8101 caggtggaga ggttaaagca gatatgcaag ttgttgatgt ttattatcgt aagggcgata
     8161 aacttcaaga aaactgggtg ttaattgata ttccttattg gttgaaacaa caagggcttg
     8221 atattcttga gagaactaaa agtattttta atgcttagtt atgcatacgt attctaaaat
     8281 aaagggggat ataaagtggc atctaccaac aaaaataatg caacaagtaa agaagaagaa
     8341 aaagaagttt ctacaagtgg gcttgaatca tgtacggtta aagaaaacaa agctaaaatg
     8401 aatcaaacta attttagtaa tataaatgaa aatcaaacaa atgagaataa aacgaacaca
     8461 tataaaagaa atatagataa aggaaatata gataaaggga atatagataa aacaaacaca
     8521 aataaatccg acataaataa agttaacata gatacagtgg atacagataa attaaataca
     8581 aatactctta ctaaaaaaaa taaaaaagtt atatttaagg gggaagataa tatgtcatct
     8641 acaaaaattt actatggaga ttcattagaa gtaacgcctg ttggagtaat ggattacaat
     8701 gatttttcaa aacagacaaa aagggaacag gaaatacctg gatttgattc taagtataga
     8761 gattttgtag attatattat gaagattaca cataatatct gggaagaaaa aggtataggt
     8821 gttatttatg atacatatca caataatgtt acaatgcatt gtggctcttc aaatttagtt
     8881 ggtattaaag atgttatttc caatactctt caaacattac atgcgtttcc tgatagaaga
     8941 ttaattggtc aaaatgtaat atggtctaac tttggtgctg atggtttttt atcttctcac
     9001 cgtgttttgt ctacagcaac taacttaggt gatagtaatt ttggaccagc aacaggtaga
     9061 aaaataaact ttagaactgt aattgattgt gccacaacta acaatagaat ccacgaagaa
     9121 tggttggtta gagataattt atggattgtt actcaattag gattaaaccc tcaggaagta
     9181 gcaaagagta tggcaaaggc aagtgaatct aaagtgctta gtttacaatc aacttatggt
     9241 atctgtgaat ctatggatgg tcaatttatg ccaactaagt atcaagcaaa agatgattct
     9301 gctggcgaaa tgatgcttga aatgacaagc cgtatttata attataaata tataaatgaa
     9361 gttaaaaaat actatcatga taatgcagta gtacatttta tatgtgataa agatttaaat
     9421 ggttatgatg agattcaagg aatgattgta agtttacttg catcaattcc aaatggaagt
     9481 tatgaagtgg aaagagtaac ttgtaatcaa agagaaaaaa atgaaggtta tgatgtatct
     9541 gtaagatgga gattacgtgg aataaatgaa ggtataggat tttttggaca gccttctgga
     9601 aagcatatag aagtaatggg aatcaatcat tatcatatac tacaaggtaa agtaaaggag
     9661 gagtggataa cttttgatgg tatggatgta ttaaaacaaa tgtatatggg agtagaagaa
     9721 taaagctgtt tagagtataa atagttttga aatatatagg gaagtattgc tttataaaat
     9781 ttaagtgggg aatgtatatg aaaaatagat gtttaaactt ttagcaaaat tatgactaaa
     9841 tttaaaaggg ggaattataa aaatatgaaa acaacggttg aaatagaaaa tgatatcata
     9901 ttaggaaaag actattcaaa cctaaaaaga ggaattgcat ttttttcaat tgctttaata
     9961 tacttttttt attgctacaa ttttatggtg ggtactttta ttaaaccaac aatgatttat
    10021 gctttagcag atgggggatt tggtttttca ttaaaacaaa cagaagaaat atttgcagtt
    10081 atgtcttttg gtacaattcc aggtacattt atttttgggg tgatttctac aaaaattggg
    10141 aagaagagga ctttaattag cgttgcttta ctgattggat tgacaacatt tataccaatg
    10201 ttatctccta caaatattat gttatggaaa atagcacgtt tgtgtacagg agtagtgttg
    10261 ggaggcgtat ttggaacagc tatgccttta gttgcagata tgtttccaag taaatatcgt
    10321 ggtaagttag ctgctatatt aactgcttta ttttcattag caatgatttt tggtgggaaa
    10381 gtatatggcg ttttaggtga tgcaaattgg caaatattga tgtatactgc gattatacca
    10441 cctatagttg gagctatctt agcaattttc tttgtgccag atgatttgga gtatacaaag
    10501 gaattagtta aaaagggaaa agaaactggt gaaaagatta gctatataag tatgtataag
    10561 ggaaaatact tatggattgg attgggaacg attcttttat caggtgcaaa ttttacagca
    10621 tattcagcat tttcaaataa tgcaactaca tacctagtga caagaatagg aatgtcagca
    10681 gcagtggctg ggtctatata tagtttacaa ggaattggtc aattagtagg atatttattc
    10741 tggggttcaa ttgcagataa atttggaaga aaaatacctt ttataggtat ggcattagca
    10801 gcagtatttg tttttatata tacaaaatta ggtggagata atacaacaac attctatatg
    10861 atatcagtat tactaggtgt tgctgttgga tattctggag catggggagc atactacaca
    10921 gagttgttcc caagtaaata tcgttcgttg tcatctggta tgtcatttaa tggaggaagg
    10981 attatatcta cgtttgcaat acctgctata gctggtacag cttctggtac tttaggtatg
    11041 atgactatct tttacatatc aatcgcagtc tttgtagcag gtgctattgt atggttattc
    11101 ttaccggaga cgttaaataa taaaaaataa aatactagga atttattttg ttacttagaa
    11161 aggggtggct tatgatttca tcaattgatg tatgtattat aataggatat ttgctattaa
    11221 tgttagttat tggttattat tcaggaaaag ataataaaaa tcaagaagat tatttcttgg
    11281 caggtaggtc aatgccatgg attccaattg ctttatcagt tgcagctact atgattagtg
    11341 caaatggctt tataggtggt cctggatggg catatgtaga tggaatgtat ccagtaatgg
    11401 ttaatattac agtaccttta gcaatatttt ttgcactgag cattaccacc ccagttatct
    11461 ataaattaaa aataacctct atatatgaat atatgggact tcgtttagga aattattcaa
    11521 gaggattaac tattattcaa ttttttatta attcattgat tcaagctagt tctatggtat
    11581 atattccagt gcttattatt caaatgatta ctggctggtc actttatgct ttagtcccaa
    11641 tagttgtact tgtatcaatt atatatactc tattaggtgg gattaaggca gttatatgga
    11701 ctgatagtat tcaaatgata gtagtaataa gtgctgtatt tatagtaatt attgtagcct
    11761 taaaaggaat gaatctaagt ttctttgata cattacaaat tgcacaacag agtggaaaat
    11821 taaatacatt tgatttcagt agggatattt cagtgacaaa tactttttgg gctactttaa
    11881 ttggtggaac tgtaatgtgg ataagatact tttgttttga ccaatctcaa gtacaaagag
    11941 ttttaacatc taaatcttta aaatgtgcaa aaaattcttt tgtagttagt gcatttgtta
    12001 tgaatttagt ttactacttt atgctattgg taggagtaat tttatttgtt ttttatgggg
    12061 gaaggacatt tgaaacttca aatgaaataa tgattacttt tattttaaat gaacttccag
    12121 taggagccat tggaattatt attgcaggtg tgtttgcagc agcaatgtct agtatcgact
    12181 ctatattaaa cagtatgaca actgttttta cgaaggatat ttatgagttt tatttcaaaa
    12241 aagacaacaa agaatcatca ttaaaagtta caatgattat aactgtagtt ataggagttg
    12301 ttatgacagg ttttattatt atgggatttg gaggaagcat caaatcaatt cttgaccttg
    12361 ttggtaacta tatctcatac tttgctggac cagctacagg tgcatttgta ctagcaatgt
    12421 ttacatataa agctaatgat aaaggagtat ctattggttt tattgtaggg ttagttttag
    12481 gattttttat ttctaataaa tataatgtga gttggttgtg gaatccagca ataggtgcta
    12541 caataacatt gatatttgga tatattttta gtgtcatttt aaagaaaaat cataatgcag
    12601 atgatattaa aaaatacact gcatttggta tgagaaatca ccttatttct caaggaatgg
    12661 ataaagtaga tggagtatct atagtgccat tttctttagg taaacaagaa ctaattgtat
    12721 tagctttttt tattatccaa tatattatat tatttttgat acaattttaa gaagaaatac
    12781 tagatattta aggagaaata ctaaatgaat caaaagaaag ttcattataa taaatcggct
    12841 acctcaaaag atgttgcaag attggcagga gtatctcaat catctgtttc aagagcattt
    12901 ggtagtgcaa atggaaaggg cgtaaaacct gaagtaagag aaagaatttt tcgtgtagca
    12961 aacgaaatag gatatgttcc taatttggta gcacggggaa tgattagtgg aaaaactaat
    13021 gttataggat tgatagttgg tgatagtcta ggtccatttt acaatagaat tatcaattta
    13081 tttgtagaaa aaattcaaga gataggtaaa cagtgtctcg tttttaaagt tcctagacaa
    13141 caaagtatag atagtataat ttcaaaagta attcagtttc aagtagaagc tgtgattatt
    13201 acagcttcgg ccatgaataa ggtgatggct gagacttgtg aagaaaacaa tattcctgtg
    13261 attcttttta atcgttttat acctggtata aaaataagta cagtctatgt agacccaatt
    13321 gaaggtgggg gaatggctgc tgaatatctg cttaagaaag gtcataagaa tataggatat
    13381 attcaattta cgagagaaac aagtgaagaa atggaaaaga aaattggatt ttattctaag
    13441 ttaagacaaa gtgggattca taaccttaaa gaagaatctg caaactatga ttatgattct
    13501 ggatatgaag caggtaagag aatgttagca ttatcaaatc ctccaacagc aattttttgc
    13561 acaagtgact tgatagctat tggtgtaatg gatgctgcaa ggtttgagta caagttgagg
    13621 gtgccagagg atttatcagt gataggatat gatgatattc aaatggcttc atggaagagt
    13681 tataatttaa cgacgattag acagccacta gatttgttga ttgaaaaaac aattaacata
    13741 cttaagtcct tattaaatga agaaaatcca gagtcagttg ttgaaatgtt aaaacctgaa
    13801 ttgattgaaa gaggttctac actttaagtg gtagatattt aattaagtgg tagataccta
    13861 attaagttgt agatatctga taagaaattt ttaagttttc aatcgttcta aattgtgagt
    13921 ataaaaatct actaaattta gttatgtaaa atataaatta taagtgtaga aactaggcta
    13981 ctagctttta taccacttca aacattactg gaggtagtta agtttacatc agtttagttt
    14041 tatgtagata taatattctg taaatagaca aaattaaaat atgtaagtgt ctcaaaatga
    14101 aatttttagt ttatgaggca cttttttgta taaaatcaaa tgtattttta taactttaac
    14161 aataaaaaga ggcttatctc tattttgaga cagcctcaaa tttttaaaac tatattagtt
    14221 tacagcttct tttcctatca aatcttttaa ctcttcatga gtcatagttt ctttttcaaa
    14281 taagaattta gaaacagaat gtaaatcttc aagattatcc tttaacatct ctaaagtctc
    14341 tttataacaa atttcaacta tacgatttgc ttccttttga accttatcac ataagaaagt
    14401 cttatcattt ccatcaatag tcataaatcc taagttactc ataccatatt cacaaaccat
    14461 ttggttagct atttcagtga ctttctttaa gtcgtccttt gcaccagtag atttatgatt
    14521 aaatattaat tcttctgaag cctttccagc aagtaatatt tttatttttc caatcaactc
    14581 atccttagta taaatatatc tatcttcatc aggtaattga agaacataac ctaatgcttg
    14641 tcctctagga actatagata ttttttgtat aggacaaatt cctactatat cacttacaag
    14701 agcatgtcca gcttcatgat atgctactat ttttttctct ttttcaacca atgcagagtt
    14761 tttagattct agccctgcaa taactctttc aagtgccttg tcaaaatgtt ctgatgtaat
    14821 acactcactg tcatctctaa ctgcaaatat agctgcttca tttgctatat ttgaaagatg
    14881 agccccattg aaaccatgag tttttttagc taaaagttct agatttacag atttgtctat
    14941 aggtttgtca tctgtatgta cctttagaat ttcaaatcta gtgtgatagt ttggtgcacc
    15001 tatatgaatg tgtctgtcaa atcttcctgg tctaagtaaa gcttcatcta ataagtcaag
    15061 tctattggta gcacctatta ttaatacatt ggaatcttta ttaaatccat ccatttcaac
    15121 taaaagttgg tttagtgttt ggtctttttc gttgttactt tcaagatgtc tctttgctcc
    15181 tacagcatct atttcgtcta taaatattat acttggagct tcttttctag ctttttcaaa
    15241 tagagttcta actctttttg ctcccacacc tacatatttt tcaacgaact ctgaaccagt
    15301 aacattgaaa aatgatgagt ttgtttcacc agctacagca gatgcaagta gggttttacc
    15361 tgttcctgga ggaccataaa ataatactcc tttaggtatt tttgcaccca ttttttgata
    15421 tttttgtggt gacttcataa aatcgactat ttcaaatagt tcttctttta cttcatctaa
    15481 tccagcaaca tctctaaatg tagtctttgg ttttgtagaa agtgaatcat ctgtttgatt
    15541 atctctttcc atttttgtct gtgcaaagac aggagctgga ttgttgattt tcttaaaaaa
    15601 gttgtttagc attttcatat tcacacctca ggtaattaat tattgttaat caattttata
    15661 ttttccatat ttactatttt ttattattta tttttcatgg aaaaaatata catgttatct
    15721 aaataaaaat aaatttgtaa gatgtatgaa aaaatgaatt tatgtatata gagatttcta
    15781 cttatgtatt gaataaagta ttacaaatta taaattatgt attgattata tattgagtaa
    15841 agtattataa agcatgtatt gattaagtat tgaataaaat attacaaatt tagttgaaat
    15901 gaaaatgata aaaaatcttg tactatattt tacaaatcat ataaatagag aaattgttgt
    15961 agcacaaagt agtaggtagt atattagaat ataatatagg atttgttgtg tagtatagta
    16021 gcatattaga atataatata ggatttgtta tgtagtatag tagtatatta gaatacaata
    16081 tagaatttgt tgggtagtat agtgttatat tagaatacaa tataggattt gttatgtaga
    16141 atatatagag tcatgtagaa tataaatata taaaaggatt ttgggtataa atttaaaaat
    16201 taatagcaaa atgagtagta tagacatata attagtagta ggaagtaatt aaatttttcc
    16261 taaacaaaaa aaatagttgc aaataatttg attaagtgat atagtagata aggtaagaat
    16321 aaaacaaaga agaagtccgc ttctcacctt acgccggagg ttagtaaggt aaatataagt
    16381 taaagcttaa ttttaattta agtttgttta aatttggtaa cttatattgc ggatgattac
    16441 gtcatccgct ttttatttta taaaaatttt ggaggtgtcc tacaattagc aaagaattag
    16501 caatcaatga acaaataaaa gataaggaaa taagagtcct ttcaccaaca ggtgaacaac
    16561 ttggagtaat gcctactaaa gaagctcaag caatggctaa tagcaaaaac ttagatttgg
    16621 ttcaaatctc gccgaatgca aatccaccag tatgtaagat aatggattat ggaaagttta
    16681 gatatgagca agcgagaaaa gagaaagaag ctaagaaaaa acaaaaaact atagttgtaa
    16741 aagaagtaag acttagacca ggtattgaac aaaatgattt aaatacgaaa gctaataatg
    16801 ctataaagtt ccttaaaaaa ggggataaag tcaaagttga acttagattt agaggaagag
    16861 aattaggaca taaagacata ggtaaagaag ttatgcttaa gtttttagat ataataaaag
    16921 agtttggaga accaacaaaa gcccctgcat ttgagggtaa taatatggtt gtaattatag
    16981 atccaaaaaa atagatgatt aactgagagg aggaatttgt catgcctaaa atgaaaactc
    17041 atagaggtgc agcaaagaga ttaaagaaaa caggaactgg aaagttaaag agagctaaag
    17101 cttttaaaaa acatatatta actaaaaaat ctgcaaaaac taaaatgaac ttaagaaaat
    17161 caactttagt aagtgatgga gatgctaaga gaatagcaca attattacca tactaagata
    17221 cagattgtaa ataataacta tagaagaggg atataaaagg aggtcataac gatggcaaga
    17281 gttaaaaaag ctatgaacgc tcgtaaaaag cataagaaaa tattaaaact tgcaaaagga
    17341 ttcagaggat ctagaagcaa attatataga ccagcaaata cattcgtaat gaaagcatta
    17401 aaaaatgctt atataggaag aaagttaaag aagagagact tcagaaaact ttggatacaa
    17461 agaataaatg cagctgctag aatgaatgga atatcttatt caagattaat gaatggatta
    17521 aaattatctg gtattgaagt taacagaaaa atgttatctg aaatggctat acaagaccca
    17581 gaaggatttg caaaattagc agaagttgct aaagcaaaat tagcttagta ttgaatcatg
    17641 agatgtaaag tctttgagtt atataaataa ttcaaggact tttttatttt ttgaaaaata
    17701 cttattagtg tcatgtacaa ccaattttat aatgataaat aaaataagca atacaataga
    17761 attttatgag atttattata agaattgtta caattattta tgatagctat aaaaagtcat
    17821 agtaaaaatg atattgatgt atgttgatat atgtataaag ctttcaatca atcttgaatt
    17881 aatattatca acatgataat attatcttat taataatata aataaggggg agataatatg
    17941 aatgaaaaac taatggattg ttttgtaaac ccaattaaat gcaagttatt gattgaaatt
    18001 ttttcaaata atcgaactac agctaaacaa ttaggagaaa aatttcaaga tatatcaaag
    18061 gcaacacttt atcgttacct taataaaatg ttgaaagatg atattataaa agtagttgaa
    18121 gaaaataaaa taaggggaac tgttgaaaaa gtatatgcta tgaagttaga tatagctgat
    18181 gatgtgaaca aaattataga tgagaactct ggagaagaat atgctcaact gtttactcaa
    18241 tatatgatgg gatttttaag agaattttat gaatacgctg aaagaaagga aaaggatatc
    18301 ctaaaagatg gttcaggatt ttctgtctgt ccagtatatg ctagtattga tgagatagtt
    18361 gaagtgagta aaaaaattgc tagtatacta gaacctctaa gaaataactc gcacgaagaa
    18421 ggcagaagaa tgcattctat aggagtgata atcactccac ctaaagagga tgaagggaaa
    18481 taaatctgat ttacatgagg tagagccaat ttacacggaa aatcgtttta tgatttacat
    18541 atgtatccag agcaaagtat ctctgcttgg attgtacttc attgtatcat ttcatctatc
    18601 taatgacttg gagtggtaca atgaagtttt ttaatttttc atatcaatgc ctaaagaaat
    18661 gaactttaga ccacatatgc aattaggtta cattatacaa ttagaccaga tatacaaaat
    18721 aaaaatcagt atttttatag cagataaatt gactgttatt cttcttaaaa atcatctatt
    18781 agttattgtt agcatattga aagaaattat aggaatctat tgaataaatg aatattgccc
    18841 ataatcatat aaactgctat agtttaaaat aaagcaggac gttaaatttt atagtaatct
    18901 aaaaatttaa gagggggatt ttatgaaaat aaaatttgtt attatgccat tggtgatatt
    18961 tttaatggta ttatttgtgg ggtgtcaaag tacaaaagat acagaagtta aagcaaaata
    19021 tacagaaatt aaaatattag gtacaggtga tttgcattca attttgacag actctatggt
    19081 ttcatatgta aatgaggaaa gggaaaagaa taaaaatctg cttatggtag atgcgggaga
    19141 tttctatggt acacaaagta gagaaatgtg ggaatggtct tctggaaaaa agttaattaa
    19201 tattaaaaga aatggtagag cagagtatga tgacataatt aagagtagta aagatgaagt
    19261 acctatagtt aaagatatgg caaagttgaa atatgatgct gtagttttgg gagataatga
    19321 atttgtttca aatgataagc aaagtcttga taaactagtt tctgatttta aaaataataa
    19381 tatgccattg gtatcagcaa atatatatga acaatctgga gaaaattatg tacaaccata
    19441 tgtaatgaaa aatattaaga cagatgaggg caatgtaaaa gttggaatac taggtcttac
    19501 tataaaagaa gtaggggaaa cccttggtct tgaggatttt gaaaaggata aaaaagctag
    19561 agagcttgga gaacaagctg attacaaagg aaaattatat gcaaatgatt tagtagaaga
    19621 tgcaaagaaa tggataaaag ttatggaaaa agaaagtcca gacataatag ttgcagttgt
    19681 acactcaggg gaagaaccta aaacagatag aaatccagga aatagaataa aagagttagc
    19741 aactacagtg gatggaatag atgcaattgt agctggtcat actcatgaaa aaatagatga
    19801 acacaaatat aaaaataaat ctggagatga agtaattgtt acacaaccag gttggcatgg
    19861 agatagagta tcagagatta atttcaaatt aaataaagag aatggaaagt gggacataaa
    19921 ggaaaagtct agtaaattaa aaataattga taaagaagta agtatagttg ctactgcaga
    19981 tttacattca catttctctg ataaattaac agttgacctt gttaatgaac gtagtaaccc
    20041 aattgaacct gttgtagtag atgcaggcga cttcttagac cctcaaacag atgaaatgac
    20101 tcaatggtat aaagagtgga aaagtataag agataataat agtgataaaa cgattagtag
    20161 atgcccaatg gtcatggata tgaatcaggg aatgtatgat gcagtagtac ttggaaatca
    20221 tgaatttgta tccgaaaaag atgaattttg gtcagatgaa cgccttttag atgctgttat
    20281 agaggatttt gaacaggtgg caatttctgt gttatcggca aatatatata ggcaatctgg
    20341 taaaaattat gttaaaccat atattataaa agatgtggag acgagtgaag gtaatgtaaa
    20401 agtaggaata ttgggactta ctataaaaga agtaggtaaa ggtcttaaaa atgtaaactt
    20461 acaagagcaa tttcaatata aggataaatt gtatgcaaat gatttagtgg aagatgcaaa
    20521 gaaatgggta aaagttatga aaaagaaaaa accagatata atagttgcag ttgtacattc
    20581 aggagaagaa ccaaaaaatc caaaacatcc aggaaataga ataaaagaac tagcaactac
    20641 agtagatgga atagatgcaa ttgttgctag tcatactcat gaaaaaatag atgagcatga
    20701 atataaaaat aagtctggag aaaaagttat agtgacacaa ccaggtgagc atggtaaata
    20761 ttattctaaa attaccttta aagtaaataa agaaaagggt tcgtggatta ttaatgataa
    20821 attcagtaaa acaattgagg ttgaataact ttataaaatt tatagataaa gtaaattatc
    20881 tgatattgac atgatatata agataaagtt tctaatatta gtataatgca taatgtgaaa
    20941 tattttaata ataagagaat aaacaagaca aataaaaata ttttaacatg taagatatag
    21001 tatgaactat tatactaatg cttactttat aatttgaaca tgttagaata agtcttattt
    21061 gaaaatttta gtgtattaga gtaagtatta ttttaccagt aaaaaatatt gagaactata
    21121 tgtagatttg cttaaaaagg aatttacata tagttctttt cgtataataa atagtacaat
    21181 cttatatggt aaagataaag tgtgatatta aattttatta tcatccaaaa tctaaggagg
    21241 agtctcttat gaaaataaaa tttattatag tagcatcaat aatattttta atagtattac
    21301 ttgtggggtg tcaaagtact aaagacacag aaatcaatgt actcgccaca agtgatttac
    21361 attcaattat tccagataat ttaatttcct atgtagaaga ggagagaaaa tatgatgaga
    21421 atctacttat ggtagatgca ggagattttt ttgacatgca aagtggtgag atgaataagt
    21481 ggtttactgg tcaaaaatta gtaagattta aagatgggat accagagtac aaaaaaatag
    21541 ctgaaccacg tgaaggagaa gttccattgg ctaaaaaaat ggcaaagctg aagtatgatg
    21601 cagttacatt tgggaatcat gaatttgtat ctaatgacaa gcagagcctt gataaattgg
    21661 tttctgattt taaaaataac aatataccat tagtatcagc aaacgtatat gaacaatctg
    21721 gagaaaacta cgtaaagcca tatgtaatga aaaatataaa tactgacaag ggaactgtaa
    21781 aggttggtat acttggtctg actataaaag aagtagggga acgttcaagg tttaaaagtt
    21841 ttgaacaaga taaaaaggct agagaacttg gggaacaacc tcaatacaaa gggaaattat
    21901 atgcaaatga tttagtagaa gatgcaaata agtgggtaaa ggttatggaa aaaaaagaaa
    21961 agccagatat aatagttgcc attgtacact caggtgaaga gccaaaaaat cctaaaaatc
    22021 caggaaatag aataaaagaa ctagcaacaa ctgtagaggg aatagatgct attgtagcag
    22081 gtcatacaca tgaaaaaata gaacagcata catataaaaa taattctggt gaagaagtaa
    22141 tagtaacaca gcctggagct catggtaata gtatatcaaa gattaatttt aagttggata
    22201 agaagaatga taagtggttt ataaaagaca aatatagtga attaaagatt tttggaaagg
    22261 aagtaaatat aattacaact tctagtctga atccaaaatt ttcagatgaa atggcagtta
    22321 atttgtttaa tgaaagagat agagatgttc aacctatatt tatagatact ggagattttt
    22381 taaatactaa tacaaaagaa atgactaagt gggctaaaga gtggcaatac aatgaaaata
    22441 aaggcatcta taaaaaaata aatgaatggc caattgtata tcttggttat gatgctgtag
    22501 tacttggtag ccatgaattt acagaggata aagagacttt tgaggaaaaa aaatctacat
    22561 tggattatat tatagaaaac tttgaagaaa tgaagatacc agtattatca gctaatatat
    22621 atgatgaatc tggagaaaat tatgtaaaac cttatataat tcataatgta gaaactaggg
    22681 aaggaaatat aaaggttgga gtattaggtc ttactactac tgataaggat gaagaagact
    22741 taagtagctc aagcttaagc aaagactcaa agacttcgaa aattcctgaa gaaacaggaa
    22801 agttatatac taataatcta gtaaaagatg caagcgaatg ggtaaaagtt atgcaaaagg
    22861 aaagtcctga tgtgattgtt gcagttgtac attcagataa taatagtact ctaaaaaatc
    22921 caagtagtga agtcaaaaaa cttgcaatgt cagtagatgg aatagatgct attgttgtag
    22981 gtcatacgaa aaataaggta gaagaacata tttacaaaaa taagtctggg gatgaggtta
    23041 tagtaacaca atctggagaa gattgttatt caaaaataag tcttgaacta agaaaagaaa
    23101 atggcaagtg gaatatcata aacaaatata gtaaagcaat aaaaatgaag tgaatttatt
    23161 gatatataaa ccattattaa cactgatttt tataatataa taaatactga ttctataata
    23221 taattaacac tactttttat aatgtcatca acactgattc tataatataa ttaatactac
    23281 ttttttaaat ataatcaata ctgattccat aatataatta acactacttt tttaaatata
    23341 atcaatactg attctacaat attattaata ctacttttta taatat
//
LOCUS       DAEPHU010000065        23299 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 01A10CD0081
            SAMN05941466-rid12468953.denovo.065, whole genome shotgun sequence.
ACCESSION   DAEPHU010000065 DAEPHU010000000
VERSION     DAEPHU010000065.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941466
            Sequence Read Archive: SRR6291087
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 23299)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23299)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068158.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 22:43:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,892
            CDSs (total)                      :: 3,805
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 87
            rRNAs                             :: 8, 1, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 55
            CDSs (without protein)            :: 55
            Pseudo Genes (ambiguous residues) :: 0 of 55
            Pseudo Genes (frameshifted)       :: 21 of 55
            Pseudo Genes (incomplete)         :: 28 of 55
            Pseudo Genes (internal stop)      :: 16 of 55
            Pseudo Genes (multiple problems)  :: 8 of 55
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23299
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941466-rid12468953.denovo.065"
                     /strain="01A10CD0081"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            443..1321
                     /locus_tag="KR231_002742"
     CDS             443..1321
                     /locus_tag="KR231_002742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketose-bisphosphate aldolase"
                     /protein_id="HBH0005104.1"
                     /translation="MLINMKEMLKVAQENQFAVPAFNIGSGQILKAVVQSANEKNAPV
                     ILAIHPNELSFLGDSFVASCIEEANKSKVPMVIHLDHGENKEQILRAIRCGFTSVMID
                     GSHLPYEENVAISREIVEIAKGLNVSVEGELGTIGTTGTSSEGGTDEIIYTDSKLAKD
                     FVEKTGVETLAIAIGTAHGIYPKGFKPELKLDLLKEIREVVDIPLVLHGGSSNPDEEI
                     AQAVKLGVCKINISSDVKSAYYKKCRELLEQNPSLYEPDTIYPPCIKSAREVIEFKMN
                     LFNAIDKLKCFYKNKN"
     gene            1357..3252
                     /locus_tag="KR231_002743"
     CDS             1357..3252
                     /locus_tag="KR231_002743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBH0005105.1"
                     /translation="MIGKILRSDCIVLDKQLQTKKDVINYMANHLYHGNYINNKEKFI
                     ADINKREKESSTNMGNLIAIPHAKSNVVNQPVMMYLRTDREITDNDGQKLRSFFMIAV
                     PESGSDEHLKIISKLATYLMEENFLKHLLSAETPYEILSIFNNKAAESGDFSNNQNKG
                     LIVGITGCPTGIAHTFMAKKALEEAGQELGYEVKIETHGAIGVENKLTKEDIKRAEYV
                     IIACDKEVQLSRFIGKKVLQKKVVDAKNVSLAKNLIINAENGMAKEIKPGGKTLEDSK
                     EMLQGSEKKGVYKHLMSGVSEMIPFVVIGGIGIAIAFMFGIFASDPTHETYNPIAGFF
                     GQLGGDSAFKLFIPILAGFIAKSIAGRQGFAPAMIAGFMAVIGGSGFIGGMVAGFATG
                     YIALGVMKITENLPDVLKGVNAVLICPLLIAFTSGAIMFFVVNTPASWLNEALQSWLQ
                     SMSGTNKVLLGAILAGMMASDMGGPINKTASAFGLAMFSSNIFEPSAALMVGGMVPPL
                     AISLAMLIFKNKFTKEERKSSLPTAIMGASFITEGAIPFAAADPLRMIPANIIGSCIG
                     GAICMSLDITLMAPHGGIFVIPFACSAPVAYIACILIGTVITALIIGVTKPTIRSENS
                     EVELLGA"
     gene            3520..5427
                     /locus_tag="KR231_002744"
     CDS             3520..5427
                     /locus_tag="KR231_002744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HBH0005106.1"
                     /translation="MLVSRQIEFLKLILNENKYRPIKYFKDKLNVSDKTLQKDLKMIE
                     KYLETFNIKIDIKRGYGILIEDLAKKNIDLINSLNIQSKENKSLSVEQRRMEILKYLL
                     LNSNNITSINQLADKYYVSKTSIVNDFKYIEAWIKEYNLKLNKTLEGTKIIGKEVDIR
                     KSIAKMMDDLLDENYEQHDISELTRLDSATFSALINLFDIDSIIFVETIITELEYNLG
                     YTINQPYYINLITHILICLKRIEEGNQIESQEEREISVDNLDELVYKNVSTLIDKIEN
                     RYRVKITKDEIMYIYIFLVSSGFSSENNSSYNDESDRLSESEKVSSIMIENMSRFLNI
                     NLKNDDLLQKSLASHVRPMLNRLRYDIQIKNPLLGEIQERFSDVLGLCMMTINIMTEY
                     DNLKNISIDEVSYLATYFQAAIERNMSSKRVIVVCHTGYGTSQLLAARLKREFPEWTI
                     VDIVPMHQLSKRNLDDVDFVISTVNLDLKDKLHIVVSVLLMENDINNIKNALLSKPKK
                     SMNLDTNLLGMYLEDNIYFNFDVAQMESLIGVNLGSKYESISLGKDLNIYIHKQSKLN
                     KGIMNINNVTRTIDIYLEISNQSFLKNILMEISNLYRQKNYINYIIDCKSKEDIKILF
                     KNNLLEKTNGN"
     gene            5417..5866
                     /locus_tag="KR231_002745"
     CDS             5417..5866
                     /locus_tag="KR231_002745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBH0005107.1"
                     /translation="MEIREILTEESIILDLKSTTKEGIIQELVDKLYDTGSITLKSKF
                     IKALKHREKIGSTSIGYQMAMPHGKTKYVKKASIVIGKSKKGVDWPSIDGLPVKVIIM
                     FAMPQSGGNEDMILISKIAYILGGKNIGERLLNANTKKEILDIFYEV"
     gene            5966..6853
                     /locus_tag="KR231_002746"
     CDS             5966..6853
                     /locus_tag="KR231_002746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HBH0005108.1"
                     /translation="MAIYLEMPKLIHEFPFRSLSNEGEVLTTPHWHKEIEILLITEGV
                     VNLFINDKPMQLKKGEIVIIKGGDIHYILPSPGSERLVFQFDISFFNDLILLNEEKES
                     LINLFSSIKKCSRDWSAKIRKSVFDILIDIYNEDLYKIEGYSYAIKGKMYNLIPILYR
                     QIPREIEENTVEYEINSKEILERLNNIFKYVEKNYKQPIKLEDVSYEVGFSVYYFTKF
                     FKKNTGKTFITFLNEYRLEKAKWILLNNNISIVDLVEEVGFGSTKTFYRVFKEKIGVS
                     PLEFKKRYNSLEKKGSVSK"
     gene            7256..8704
                     /locus_tag="KR231_002747"
     CDS             7256..8704
                     /locus_tag="KR231_002747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="family 1 glycosylhydrolase"
                     /protein_id="HBH0005109.1"
                     /translation="MKLGKDFLWGGAISANQSEGFYLDGGKGLSQFDKLPLNDKRLKD
                     VCLDEDNILNENNQYYPSHIGIKFCENYKEDIAMLAEIGFKCFRFSISWSRIFPTGEE
                     SEPNEKGLQLYDNIIKELKKYNIEPLITISHFDIPYSLVEKYSGWADRRVVNLYVKYA
                     EILMKRYKDDVKYWIPFNEMNMIMHIPYIGAGLTFIADENQLQKKYQAAHHQLLANAK
                     TIEIGRYINKEFKFGCMLAAGKTYPYTCKPEDVFATLEHERHNLFFSDVQVRGVYPSF
                     MNYYLKSNQIKLIIKEEDLSTLKDNTVDFVSFSYYSSACSSARAEGLEKSKANGPETI
                     KNPYLPKSNSVWQNDPVGLRITMNQLYERYQLPLFIVENGLGTQDIVNEDGKIIDDYR
                     IDYMKEHIKNMIIGVNEDGIELIGYLMWGCIDVTSVSEGKMTKRYGIIHVDSDDYGRG
                     SFKRTKKQSAFWYKKVIETDGEILFNDMETHA"
     gene            8730..11120
                     /locus_tag="KR231_002748"
     CDS             8730..11120
                     /locus_tag="KR231_002748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 65 protein"
                     /protein_id="HBH0005110.1"
                     /translation="MSLIFTTKDQLIEQGFSKDTIKSNETLFTLANGHLGVRGNIEES
                     DFNNEYVDNMGTYVNGFYEESPITYGESAYGYAKQNQTICKLPNAHIVNFSIEGDCFD
                     LSKGITSEHSRILDLNEGILKRSFIWENSRGRKVKVSIERLVSQDIEELMMISYTITP
                     LNFNGKIKFKNKMENSMEKFNCEKVEDPRVASINKKQFKINVKKYNNKYFMNLVTERS
                     RLGLWCGFDSYITCGNITNETYNVSDECIEREIEVYAKKDERLNLEIVVGYSRVYSDL
                     NLNEERLKSLECLESLKCLESEAHLKSLELVLREACNIGFDKVKNIQRKKMNEFWTTS
                     DVEIEGDKTLQLGIKTNLFHIYQSVGRDGKTNISAKGLTGDGYEGHYFWDTEMYILPF
                     FIYTQPSIARALLDYRYSILDASRERARELGINKGCLYSWRTINGNECSAYYPAGTAQ
                     FHINADIAYGIRTYFEATNDEEFMMQNGLEILIETARFWVEFGDYIESKNNKFCINGV
                     TGPDEYTAIVNNNYYTNLMAKYNLIYAVQMVDKFKHNLFSNEVFRKVKLQEYEVKNWI
                     NAAQNMYLPYDEEKKISKQDDSFLEKSVWDFKNTPKEKYPLLLHYHPLTIYRYQVNKQ
                     ADTVLSALLFPDEFSLEQKKRDFEYYEKITTHDSSLSRSIFGMMASEIGNHEKAYNYF
                     MDTALMDINNLQKNTSDGIHAANMGGTWMSLVYGFAGMKIKNDKLSFEPRIPKHWKNI
                     KFNILFRDNLVSVNIEEYKSYYKLIKGRNITILHDNKEIKLSKNIIEVNNCFKGSN"
     gene            11122..11793
                     /gene="pgmB"
                     /locus_tag="KR231_002749"
     CDS             11122..11793
                     /gene="pgmB"
                     /locus_tag="KR231_002749"
                     /EC_number="5.4.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-phosphoglucomutase"
                     /protein_id="HBH0005111.1"
                     /translation="MKAVLFDLDGVITDTAKYHFEAWHEIAKSLDIEIDETFNEKLKG
                     ISREESLDKILLSANKVDSYTKEEKLKVCEEKNNIYIKLINSLTYKDILPGINELIKE
                     LKKNNVKLGIASASKNAPRILESLGIKDEFDCIVNPSLLKRGKPYPDIFIEGSKILNL
                     KQYDCVGIEDSYSGIKAINAANMTSIGVGKKEVLGKCDHIVEDTSLLNYNTLLQAWSK
                     KINLD"
     gene            11832..13202
                     /locus_tag="KR231_002750"
     CDS             11832..13202
                     /locus_tag="KR231_002750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HBH0005112.1"
                     /translation="MKNKYEEVAQLIIDGLGGKDNIIDLTHCMTRLRFILKDEKKVNA
                     DKLKSIDKVVGVNSTSTQYQVIIGNEVGVVFNAIINKGINTTGDIKSDIKNKNKKNSI
                     LNNIIDTITGCMTPMIPALTASGMIKVILSLCTTFNWLSSNSSTYRVLDIIGDVAFYF
                     MPIILAINAAKKFNVNTSIAVIVVGVFLHPNFSAWVSSGDPISFIGVPIQDVIYAASV
                     IPALLTVWMMSYIEKFIDKLTPSMLKTILNPTLVLLISAPIALIVIGPIGNFLGEGLA
                     SIINLLQGRLGFIMVCLLAAAMPFIVMTGMHHALTPIFISAFATTGQESLILISQVCA
                     NLAQGGATLAVALRSKDSKMKQLASAAWISAIMGITEPALYGVTLKLKKPAMLASIGA
                     GIAGLFAGITHVTLYVPQNSIMAVLGLSGEKGISNIVNGLIVIFIALVAPFIMTYVFG
                     VEKNVK"
     gene            13549..14391
                     /locus_tag="KR231_002751"
     CDS             13549..14391
                     /locus_tag="KR231_002751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HBH0005113.1"
                     /translation="MIINKILNNNVVITLDDNDEEVIVMGKGIGYQKSKGNLIDKTKV
                     NKVFRISNKEISNKLQELLNNIPIEHMKLSSEIIEYAQIKLNKKLNESIYISLSDHTY
                     SAIQRMKEGINVKNAILWEIKRFYKEEFEIGMKALDIIENKTGIKLPEDEAGFIAFHI
                     VNAQLSEGHTLASDITKLIQEVLSIVRYHFRIEFHEESVFYYRFIMHLKFFAQRLLLD
                     SAHEGETDKELLSIIKSKYNKEFECVVKIKNFIKKQYNYILTDDELIYLTIHLAKVVK
                     DSNM"
     gene            14536..16464
                     /locus_tag="KR231_002752"
     CDS             14536..16464
                     /locus_tag="KR231_002752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HBH0005114.1"
                     /translation="MGKYKQLAQEIVNNVGGKENISGLVHCITRLRFTLKDESIANDN
                     VLKNMEGIVTVMKSGGQYQVVIGNHVEAVYKDVVEIIGLDDSSTSSETKKSGNILDKG
                     IDIISGIFQPVLGIMAACGMLKGFNALFVAMGLYSDVSGGYMVINAAGDALFTFLPLF
                     LGYTSAKKFGLKPMLGLALGAAVCYPAIQGSSISAGADVMYTLFKGTMFASPVYIDFF
                     GLPIVSIDYTGTVVPIIFIVYFASRCEKLFNKCVPNLVKFFFVPMLTLLITVPVALIV
                     IGPIATFGSTLISQIVISIRDFSPLLAGAIVGFTWQILVIFGMHWGFIPVYINNVMTL
                     GYDNVMMPFFACTFASSAVVLAIFFKTKDKKLKEMAIPNFISGIFGVTEPAIYGILLP
                     LKKPFIISCIASGIGGAFYGFFNLRKFITGGMGIFELPAMIEPDGGMGNLIVALSGIA
                     ISMVVAFVLTMILYKDEKVEESKKVRNKGKEEIKEVKSTKLEREIVTSPIKGEVLKLS
                     DIEDAAFASGVLGQGVAIIPSDGKVVAPVDGVVTTLFPSLHAIGILSDTGVEVLIHIG
                     LNTIQLEGRGFEACIKQGDRITKGQTILNFDVYAIKELGYSTVTPIVITNSSQFLDVV
                     ETESKNIELEDNLITVLF"
     gene            16525..17952
                     /gene="ascB"
                     /locus_tag="KR231_002753"
     CDS             16525..17952
                     /gene="ascB"
                     /locus_tag="KR231_002753"
                     /EC_number="3.2.1.86"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HBH0005115.1"
                     /translation="MSFKNDFLWGGATAANQCEGGYNEDERGLANVDVCPTGKDRTAV
                     ITGKLKMFDFDDEHYYPAKTGIDMYHNYKEDIKLFAEMGFKVYRMSIAWSRIFPKGDE
                     ETPNEKGLQFYENIFKECKKYKIEPLVTITHFDCPMHLVKKYGAWRNRKMIGFYEKLC
                     NVIFRRYKGLVKYWLTFNEINMILHAPFMGAGICFEEGEDVEKIKYQAAHHELVASAI
                     ATKIAHEVDSNNLIGCMFAAGSVYPYSCNPNDVWEATKLDRENYFFVDVQSKGKYPNY
                     ALKYMEQKGITPEMEPGDIELLNKYTVDFISFSYYNSRCVRTDENADDMAEGNIFTSA
                     KNPYLSYSQWGWPIDPLGLRITLNHVYDRYEKPLFIVENGLGAKDIADENGYVEDDYR
                     IDYLREHIKAMHDAVSIDGVDLLGYTTWAPIDLVSAGTGEMEKRYGFIYVDRDNSGNG
                     SLRRMKKKSFEWYKKVIASNGEDLY"
     gene            18399..19175
                     /locus_tag="KR231_002754"
     CDS             18399..19175
                     /locus_tag="KR231_002754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HBH0005116.1"
                     /translation="MKYQHIIEVDKELCIGCGLCKNDCPVNNIIIENKKSVIKKQDCL
                     MCGHCAAICPTKAITLTGFDEPPIELTNKPKLDSDELLMAIKSRRSIRKFKDKEVSSE
                     IIKQIIEAGRYTPSAKNSQDVSYIVLDNKKSIYENEAVKFFRKIKPIANIAIKYSKEV
                     EIDDNFFFKHAPIAIMIITKDKISGSLAASNMALMAESYGLGVLFSGYFSDVANNSPK
                     LKKLLGLKRSNHVLTTLVIGYPDVKYRRTAQKEVATVRYL"
     gene            19191..19556
                     /locus_tag="KR231_002755"
     CDS             19191..19556
                     /locus_tag="KR231_002755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HBH0005117.1"
                     /translation="MEKECQQRMQEITSKFKECRKAISAMGDETRQLILIALLESDFN
                     GIRVGEITKKTHLSRPAVSHHLKILKEAEIVNLRREGTKNYYYLDSKKSQWKSLTELI
                     NLIFVGIQHISENDIRKGD"
     gene            complement(19722..20471)
                     /locus_tag="KR231_002756"
     CDS             complement(19722..20471)
                     /locus_tag="KR231_002756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440038.1"
                     /note="N-terminal region resembles flavodoxins. C-terminal
                     ferrodoxin region binds two 4Fe-4S clusters; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EFR1 family ferrodoxin"
                     /protein_id="HBH0005118.1"
                     /translation="MILYFSGTGNSRYVARKIAQELNDELISLNQLIKEEKTDELISA
                     DKPFIFVCPTYAWRLPIVVTDFIKETKFLGSNRVYFVMTCGGDTAKSINYIQKLCKYK
                     EWQLKGMAEIKMPENYIALFSTTDKETSKQMIKEADKQIYRIISDIRNENEFETITPS
                     GLGGTIKSGIINTVFYKTIISAKGFHYTDKCIGCGKCVELCPLNNINLKNKKPVWKNN
                     CTHCMACICGCPTEAIEYKNKTQNRERYYLE"
     gene            20929..21354
                     /locus_tag="KR231_002757"
     CDS             20929..21354
                     /locus_tag="KR231_002757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBH0005119.1"
                     /translation="MINENLKSLRKINQYTQEELAEKLNVSRQSIAKWESGESIPDIC
                     SCIKLAKLYNVKLDDLVNHSEEKTGIIVPPKGKFFFGAVVVGERGQIVIPKEAREVFN
                     INAGDKLLVLGDEERGLGIVHQRDLINFIGHVGVVRKEE"
     gene            21386..22573
                     /locus_tag="KR231_002758"
     CDS             21386..22573
                     /locus_tag="KR231_002758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosyltransferase"
                     /protein_id="HBH0005120.1"
                     /translation="MSKIVFFSIPAYGHTNPTIEVVRELVDRGNEVLYYSFNEFKDKI
                     EGAGAKFICCDKYLPELLPGDEKKIGKDFPGLIEMIVDTTISLDEKVCRELKDFNPDC
                     IVSDSLSFWGKLFAQKLNIPYVCSTTTFAFNKHTAKLMKQNFIEIIRMIFGVRRINKK
                     IKLLQRKGYEVKNFISIVSNDNDTDTIVYTSKEFQPMVETFSSKYSFVGPSVSKLIIE
                     PKERKRKLIYISLGTINNKNVSFYKNCISAFKDSDVDVIMSVGRSTDIKSLGNIPNNF
                     EVKNSVEQIAILQKTDVFVTHSGMNSVNESLYYGVPMVLFPQHSEQRMVAKRVVHLGA
                     GIMLKEDKSESIKKAVFQVINDNEYKENATKLSKSFYNAGGSKKAADVILQIICNSRQ
                     VDI"
     gene            22765..23169
                     /locus_tag="KR231_002759"
     CDS             22765..23169
                     /locus_tag="KR231_002759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3139 domain-containing protein"
                     /protein_id="HBH0005121.1"
                     /translation="MKKYKVIFIVLIIGIISVTGFVVYKNCIKPWKDAETYIDKYMVK
                     QDISKDNIKSITKEKAKKASYEGILYKVYYKDDPRYEYQYFYSDNYYALYVNKVMLQI
                     YDMENNNKLLRSNEELKSVKYPLIYLKYKPDK"
BASE COUNT         9317 a         2427 c         4086 g         7469 t
ORIGIN      
        1 gtcctattta atttctattg taactaatat gcaagaattt aagatagaag tatctatgac
       61 ttatggtgta ttaataattg gtatctgcta tctagtatct ttttaatttt tttgattcca
      121 atatagtgct aactacgata cgaatatctt taaatttata gctaaactat ctaattgttt
      181 attggaaaga gttaagaagg ctaaagcata aaacacttaa aaagagaaga tgtatatgag
      241 aaatataatt aactatgatg cagacttcta aaaattattt agtgaaaagg aacttagagt
      301 gtataataaa agttcctttt cactaaggaa aacgattgtt attttctgat cttcattacc
      361 ctgatattat ttaaatataa acaacaacaa aattaacaag aagcaaattc aacctaaaat
      421 ttaaaatatc gggaggtaca atatgttaat aaatatgaag gaaatgctaa aagtggcaca
      481 agaaaatcaa tttgctgtac cagcatttaa tataggaagt gggcaaatac ttaaagcagt
      541 agtacagagt gctaacgaaa aaaatgcacc agtaatactt gcaatacacc caaatgagct
      601 aagttttcta ggagatagct ttgtagctag ttgcatagaa gaagcaaata agagtaaagt
      661 acctatggta atacacttag atcatgggga aaataaagaa caaatattaa gggcaataag
      721 atgtggattt acatcagtaa tgattgatgg ctcacattta ccatatgaag agaatgtagc
      781 tatatctagg gaaatagtag aaatagcaaa aggattaaat gtgtccgtag aaggagaact
      841 tggaacaata ggaacaacag gaacatcaag tgaaggtggt actgatgaaa taatatatac
      901 agattcaaaa ttagctaagg attttgttga aaaaacagga gtagaaacac tagctattgc
      961 aattggtaca gcacatggta tatatccaaa aggttttaaa ccagagctta aactagattt
     1021 attaaaagaa ataagagaag tagtagatat acctttagtt cttcatggtg gttcatcaaa
     1081 tccagatgaa gaaatagcac aagcagttaa actaggagtt tgtaaaataa atatttcgag
     1141 tgatgttaag tcggcatatt ataagaagtg cagagaacta ttagaacaaa acccaagctt
     1201 atatgagcca gatactatat atccaccatg tataaaatct gcaagagaag ttatagagtt
     1261 taaaatgaat ctattcaatg ctatagataa gttaaagtgc ttttataaaa ataaaaatta
     1321 attatgaggt aacaaattaa aaggagggga gaatttatga taggtaaaat actacgaagc
     1381 gattgtattg tactagataa acaattacaa acaaaaaaag atgtaattaa ttatatggca
     1441 aatcatttgt accatggaaa ttatataaat aataaagaaa agtttatagc tgatattaat
     1501 aaacgcgaaa aagaatcatc aactaatatg ggtaatttaa tagctatacc tcatgctaag
     1561 tcaaatgtag taaatcaacc tgtaatgatg tatttaagaa cagatagaga gattacagat
     1621 aatgatggtc aaaaacttag gtcatttttt atgatagcag ttccagaatc aggttcagat
     1681 gaacatctta agattatatc taaactagct acatatctaa tggaagaaaa ttttcttaag
     1741 catctactaa gtgcagaaac tccatacgaa atattaagta tatttaataa taaagctgca
     1801 gaatcaggag attttagtaa taatcaaaat aaaggtctta tagttgggat aacaggatgt
     1861 ccaacaggta tagctcatac ttttatggca aaaaaagcat tagaggaagc aggtcaagaa
     1921 cttggatatg aagttaaaat agaaactcat ggagctatag gtgtagaaaa taagttgact
     1981 aaagaagata taaaaagagc tgaatacgta ataatagctt gtgataaaga agttcaactg
     2041 agtagattta taggaaagaa agtgctacaa aagaaagtag tagatgctaa gaatgtttca
     2101 ttagctaaaa atttaattat aaacgctgaa aatggaatgg ctaaagaaat taaaccaggt
     2161 ggaaagactt tagaagattc aaaagaaatg cttcaagggt cagagaaaaa gggtgtttat
     2221 aagcacttaa tgagtggtgt atctgaaatg attccatttg tagtgatagg tggaattggt
     2281 atagccatag cttttatgtt tggtatattt gcatcagacc caactcatga aacatacaac
     2341 cctatagctg gattctttgg acaacttgga ggcgattcag catttaagtt atttataccg
     2401 atacttgctg gttttatagc taaatcaata gcaggaagac aaggatttgc tcctgctatg
     2461 atagctggtt ttatggcagt tattggaggt tcaggtttta taggtggtat ggtagctggt
     2521 tttgcaacag gatatatagc tttaggagta atgaagataa cagaaaattt accagatgta
     2581 ttaaaaggag taaatgctgt attgatatgt ccacttttga ttgcatttac gagtggagct
     2641 ataatgttct ttgtagttaa tacgccagca tcatggttaa atgaagcttt acaatcttgg
     2701 ttacaaagta tgtctggaac taataaagta ttattaggtg caatattagc agggatgatg
     2761 gcatcagata tgggaggacc tattaataaa acagcttcag cttttggatt ggctatgttt
     2821 tcaagtaata tatttgaacc atcagcagca ttaatggtag gaggaatggt acctccatta
     2881 gcaatatcat tagctatgtt aatattcaaa aataagttta ctaaagaaga aagaaagtca
     2941 tctctaccaa ctgctataat gggggcatct ttcataacag aaggcgcaat accgtttgca
     3001 gctgcagacc cattaagaat gattccagca aatataattg gttcttgtat aggtggggca
     3061 atatgtatga gtttagatat aactttaatg gcaccacatg ggggaatatt tgtaatacca
     3121 tttgcatgta gtgcaccagt tgcatatata gcttgtatat tgattggtac agtaataaca
     3181 gcattgatta taggggtaac aaagcctact ataaggagtg aaaatagtga agttgaatta
     3241 cttggtgctt aaattataaa taatagtaaa aataattaat ggaataacaa caagtatata
     3301 gaataataat aaggatattt agaatcagtt aactacttct aaatatcctt aatttttatt
     3361 ttgaaattat attatctatt atatcaattt agtaaggtgt atcataaatt cttttatgat
     3421 acagaagtat cttagtaatt ttacatagtt agtaaatatg ttaaaatagt acttaatata
     3481 aacatagaaa tatataaaca taggtaggga gggctaagta tgcttgtgtc gaggcaaatt
     3541 gaatttctta aattgatact aaacgaaaat aaatatagac ctataaaata ctttaaagat
     3601 aaattaaatg tatctgataa aactttacaa aaagatttga agatgattga gaaatattta
     3661 gaaactttta atataaaaat tgatataaaa agaggctatg gaatattaat agaagattta
     3721 gcaaagaaga atatagactt aattaatagt ttaaatatac aatcgaagga aaataaatct
     3781 ttatcagtag agcagagaag aatggagatt ttaaagtatt tattactaaa ttcaaataat
     3841 ataacttcaa taaatcagtt agcagataaa tattatgtaa gtaaaacttc tatagtaaat
     3901 gattttaaat atatagaggc atggataaaa gaatacaatt taaaacttaa taaaacttta
     3961 gaaggaacta agattatagg taaagaagtg gatataagga aatcgattgc caaaatgatg
     4021 gatgatttat tagatgaaaa ttatgaacaa catgatatat ctgagttaac aagattagat
     4081 tctgctacat ttagtgcatt gataaattta tttgatattg attctattat atttgtagaa
     4141 actataatta cagaattaga atacaattta ggatatacta taaatcagcc ctactatata
     4201 aatttaatta cccatatact tatatgttta aagagaatcg aagaaggtaa tcaaatagaa
     4261 tctcaggaag aaagagaaat ttctgtagat aatttggacg agttagtata taaaaatgtc
     4321 agtacactta tagataaaat agaaaataga tacagagtaa aaataacgaa agatgaaatt
     4381 atgtacatat atattttttt ggtatcatct ggatttagta gcgaaaataa tagtagttac
     4441 aatgatgaat cagatagatt aagtgaaagt gaaaaagttt catctataat gatagagaat
     4501 atgtcacgat ttttaaatat aaatctcaaa aatgatgact tactacagaa aagtctagca
     4561 tctcatgtaa ggcctatgtt aaacagatta agatatgata tccaaataaa aaacccgttg
     4621 ttaggagaga tacaagagcg attttcagat gtgctgggat tatgtatgat gactataaat
     4681 attatgacag agtatgataa tctgaagaat attagtatag atgaagtttc gtatcttgcc
     4741 acatattttc aagcggcaat agaaagaaat atgagtagta aaagagtaat agtagtttgt
     4801 catacaggat atggaacatc tcagctcctt gcagccagat taaaaagaga atttcctgaa
     4861 tggactatag ttgatatagt tcctatgcat cagttgagta agcgaaattt agatgatgta
     4921 gactttgtaa tatctactgt aaacttagat ttgaaagata aattacatat agttgtatca
     4981 gtactattaa tggaaaatga tattaataat ataaaaaatg ctttactttc taaacctaaa
     5041 aaaagtatga acttagatac aaacttatta ggaatgtatt tagaagataa tatatatttt
     5101 aattttgatg tagctcagat ggaaagttta ataggtgtga atttagggag taaatatgaa
     5161 tctatttcat taggaaaaga tttaaatata tatatacata agcaaagtaa attaaataaa
     5221 gggataatga atatcaataa tgttactaga acgattgata tttatttaga aattagtaat
     5281 caaagttttt taaagaatat tttaatggaa atatcaaatt tatataggca aaagaactat
     5341 ataaactata taatagattg caagagcaaa gaggatatta aaatattatt taagaataat
     5401 ctattggaga aaacaaatgg aaattagaga aatattaaca gaagaaagca ttattttaga
     5461 tttgaaatca actacaaaag aaggcataat acaggaatta gtagataaat tatacgatac
     5521 aggaagtata actttaaaaa gtaagtttat aaaggcatta aaacatagag aaaaaatagg
     5581 ctctactagc ataggttatc aaatggccat gccacatgga aaaacaaaat atgtaaagaa
     5641 ggcatccata gtaataggta aatctaaaaa aggtgtagat tggccaagta tagatggctt
     5701 acctgtaaag gtaataatta tgtttgctat gccacaatct ggaggcaatg aagatatgat
     5761 attaatatct aaaatagctt acattttagg tggtaaaaat ataggtgaaa gacttttaaa
     5821 tgcaaataca aaaaaagaaa tattagatat attttatgaa gtgtaggtat tgtataaatt
     5881 ataaatttga ggtttttaaa ataaaatgtg tattctttta aatagtataa attaattttt
     5941 agacactaga gaggagagga tatatatggc aatatattta gaaatgccta aattaataca
     6001 tgaatttcct tttcgtagtc tatcaaatga aggagaagta ttaacaacac cacactggca
     6061 taaggaaata gaaatattac ttataacaga aggtgtagta aatctattta taaatgacaa
     6121 gcctatgcaa ttaaaaaaag gcgagatagt gataataaaa ggaggagata ttcattatat
     6181 actgccatca ccgggaagtg aaagattagt atttcaattt gatatatctt tttttaatga
     6241 tttaatttta ttaaatgagg aaaaagaaag cttaattaat ttattcagta gtataaaaaa
     6301 atgtagtaga gattggtcag caaaaataag aaagtcagtt ttcgatatat tgatagatat
     6361 ctacaatgaa gacctataca aaatagaagg atatagttat gcaataaaag gtaaaatgta
     6421 taatttaatt cctatattat atagacagat tcctagagaa attgaagaaa atacagtaga
     6481 atatgaaata aactctaaag agatattaga gagattgaac aatatattca aatatgtaga
     6541 aaaaaattat aaacaaccta taaaattaga agatgtgtct tatgaagtag gatttagtgt
     6601 atattatttt actaaatttt tcaaaaaaaa tacaggaaaa acatttataa cttttttaaa
     6661 tgaatataga ttagaaaaag caaagtggat attacttaat aacaatatat ccattgtaga
     6721 tttggttgaa gaagttggtt ttggaagtac aaaaactttt tacagagtat ttaaagaaaa
     6781 aattggagtc tctccattag aatttaaaaa aagatataat agcttggaaa aaaaagggag
     6841 tgtctcaaaa tgaacttagt tcatgaggca ctttctttta tatgaaatca aatatatttt
     6901 cagtatttca acaatgaaaa ttccattcat ttataaagtc taaattttag ttctcaatac
     6961 aacctctatt tcgaaataaa tccttttata tataaatata cagcaatata tgagaataag
     7021 ataacaataa tgaggatata aaaatgtatt tgctatatat ataattatat acatagatat
     7081 ctaatattga tatttaatat gaaagtattg aaaatagaca atattaatta tagtgagtaa
     7141 aaaatataat tggattttta aattgaatta tttaaaaggt atagtatgaa aaaaatctta
     7201 taactaaata tgagatagaa attataaaac tttatattgt gaaagaggta gatgcatgaa
     7261 attagggaaa gattttttat ggggaggggc aatttcagcc aatcaaagtg aaggatttta
     7321 tttagatgga ggaaaaggtt tatctcagtt tgataaactc ccattaaatg ataagagatt
     7381 aaaagatgta tgtttagatg aggataatat tttaaatgaa aataatcaat actatccaag
     7441 tcatataggg attaaatttt gtgaaaatta caaagaagat atagcaatgt tagcagaaat
     7501 aggttttaaa tgttttagat tttctatatc ttggtcaaga atattcccaa caggagaaga
     7561 aagtgaacca aatgaaaagg gattacaact ttatgataat ataataaaag aattaaaaaa
     7621 atataatata gagccattaa taacgataag ccactttgat ataccttatt ctctagttga
     7681 aaaatattct gggtgggctg atagaagagt ggttaattta tatgtaaaat atgctgaaat
     7741 tttgatgaaa agatataaag atgatgtcaa atactggatt ccttttaacg aaatgaatat
     7801 gataatgcat attccatata taggtgctgg gttaactttt atagctgatg aaaatcaact
     7861 tcagaaaaaa tatcaagcag cacaccatca attattagct aatgcaaaaa ctatagaaat
     7921 aggaaggtat ataaataaag aatttaagtt tgggtgtatg ttagctgctg gaaaaacata
     7981 tccatacaca tgtaaaccag aagatgtatt tgcaacttta gagcatgaaa ggcataattt
     8041 gtttttttct gatgttcaag ttaggggtgt gtatccaagc tttatgaatt attatttaaa
     8101 atcaaatcaa ataaaattaa taataaaaga ggaagattta tcaacactta aggataatac
     8161 tgtagatttt gtatctttta gctattattc tagtgcttgt agttcagcta gagctgaagg
     8221 tttagaaaaa tcaaaggcaa acggaccaga aaccataaaa aatccatatc ttccaaaatc
     8281 aaatagtgta tggcaaaacg accctgtagg gttaagaata actatgaatc agttatatga
     8341 aaggtatcag ttacctttat ttatagtaga aaatggactg ggtactcaag atattgtaaa
     8401 tgaagatgga aaaataattg atgattatcg tatagattac atgaaagaac atattaaaaa
     8461 tatgattatt ggagtaaatg aagatggaat agagcttata ggatatctta tgtggggatg
     8521 tatagatgta accagtgtaa gtgaaggaaa gatgacaaaa cgatatggca taattcatgt
     8581 tgattctgat gactatggaa gaggctcatt taaaagaact aaaaaacaaa gtgctttttg
     8641 gtataaaaaa gtaatagaaa cagatggaga aattttattt aatgacatgg aaactcatgc
     8701 ataattcatt ttaagaaagg agtgttatta tgagtttaat atttactact aaggaccaac
     8761 ttatagagca agggtttagt aaggatacaa taaaatccaa tgaaacgctg tttacactag
     8821 ctaatggaca tttaggagtt agagggaata ttgaagagtc tgattttaat aatgagtatg
     8881 tagataatat gggtacatat gtaaatggat tttatgaaga atctccaatt acatatggag
     8941 aaagcgctta tggctatgca aaacaaaatc agactatctg taagttacct aatgctcata
     9001 tagtaaattt ctctattgaa ggagattgct ttgatttatc aaaaggtatt acaagtgaac
     9061 attctaggat actagattta aatgaaggga ttcttaaacg ttcatttata tgggaaaact
     9121 ctcgtggtag aaaagttaaa gtatctatag aaagattagt atcacaagat atagaagaat
     9181 taatgatgat ttcatataca ataacaccat tgaattttaa tggaaaaata aaatttaaaa
     9241 ataaaatgga aaatagtatg gagaagttta attgtgaaaa agtagaggac ccaagagtgg
     9301 catctataaa taagaagcaa tttaaaatta atgtaaaaaa atataacaat aagtatttta
     9361 tgaatttagt tacagaaaga agtagattag ggttatggtg tgggtttgat tcatatatta
     9421 cttgtggaaa tattacaaat gagacctata atgtttcaga tgaatgtatt gagcgagaaa
     9481 tagaagtcta tgccaaaaaa gatgaaaggt taaatttaga aattgttgta ggctatagta
     9541 gagtatattc tgatttaaat ctaaatgaag aacgtttaaa atcattagaa tgtctggagt
     9601 cgttaaaatg tttagaatca gaagcacatt taaaatcatt agaattggtt ttaagagaag
     9661 catgtaatat tggatttgat aaagtcaaaa atattcagag aaagaaaatg aatgagtttt
     9721 ggacaacctc tgatgtagag attgaaggcg ataaaactct tcaactgggg ataaaaacca
     9781 atttatttca tatttatcaa tcagtaggaa gagatggaaa gactaatata tcagcaaaag
     9841 gtcttacagg tgatggctat gaggggcatt atttctggga tacagaaatg tatatattac
     9901 cattttttat atatactcaa ccatccattg ccagagcttt attagattat agatactcaa
     9961 tcttagatgc atcaagagaa agagctagag aacttggaat aaataaaggt tgcttatatt
    10021 catggagaac tataaatggt aatgaatgca gtgcatatta tccagcagga acagcacagt
    10081 ttcatataaa tgcagatata gcttatggta ttagaacgta ttttgaagca actaatgatg
    10141 aagaatttat gatgcaaaat ggcttagaaa ttcttataga aacagcaaga ttttgggttg
    10201 aatttggaga ttatatagaa tcaaaaaata ataaattctg tataaatgga gtaacaggac
    10261 cagatgaata tacagcaata gtaaacaata attactacac taatttaatg gctaagtata
    10321 atttaatata tgcagtacag atggtagata aatttaagca taatttattt tcaaatgaag
    10381 tatttagaaa agttaaatta caagaatatg aagtgaaaaa ctggataaat gccgctcaaa
    10441 atatgtattt accatatgat gaagagaaga aaataagcaa acaagacgat tcatttttag
    10501 aaaaatcagt atgggatttt aaaaatacac caaaagaaaa atatccatta cttcttcatt
    10561 atcatccatt aacaatatat agatatcaag taaataaaca agcagatact gtactttcag
    10621 cgttgctttt ccctgatgag tttagcttag aacaaaagaa gagagatttt gaatactatg
    10681 aaaaaataac tactcatgat tcatctttgt caaggtcaat atttggaatg atggcaagtg
    10741 aaattggaaa tcatgaaaaa gcttataact attttatgga cacagcatta atggatatta
    10801 ataacctaca aaaaaataca agtgatggaa tacatgctgc taatatgggt ggaacatgga
    10861 tgagtttagt atatggattt gcaggaatga aaataaaaaa tgataaatta agttttgaac
    10921 caaggatacc taaacactgg aaaaatatta aatttaatat attatttaga gataatttag
    10981 tttctgtaaa tatagaagaa tataaatctt attataagtt aatcaaaggt agaaatataa
    11041 ccatattaca tgataataaa gaaataaaat tatcaaagaa cataatagaa gttaataatt
    11101 gttttaaagg gagtaattaa tatgaaagca gtcttatttg atcttgatgg agttataaca
    11161 gatactgcta agtatcattt tgaagcttgg catgagatag caaaatcgct agatatagaa
    11221 atagatgaaa cttttaatga aaaattaaaa ggcataagca gggaagaatc attagataaa
    11281 atattgttat ctgctaataa agtagatagt tatactaaag aggaaaagtt aaaggtgtgt
    11341 gaagaaaaaa ataacattta tataaagtta ataaactcat taacatataa agatatatta
    11401 ccagggataa atgagcttat aaaagaactt aaaaaaaata atgtgaaatt gggaatagca
    11461 tctgctagta agaatgcacc taggatatta gaatctttgg gaataaaaga tgaatttgat
    11521 tgtatagtaa atccatcttt attaaaaagg ggaaaaccat atcctgatat ttttattgaa
    11581 gggagcaaga ttctaaattt aaaacaatat gattgtgtag gaatagaaga ttcttattca
    11641 ggtattaaag ctataaatgc tgctaatatg acatcaattg gtgtggggaa aaaagaagta
    11701 ctaggaaaat gtgaccatat tgtagaagat actagcttat taaattacaa tacactatta
    11761 caagcttgga gtaaaaagat taatttggat taaaattata ttaaaaatta ttttaaaaga
    11821 gaggataagg tatgaagaat aaatatgaag aagtagctca attgataatt gatggacttg
    11881 gaggaaagga taatataatt gacttaactc attgtatgac acgattaagg ttcatcttaa
    11941 aagatgaaaa gaaagtcaat gcagataaat taaaatctat agataaggta gttggagtaa
    12001 actcaacttc aactcaatat caggtcataa taggtaatga ggtaggtgtt gtatttaatg
    12061 caataataaa taaggggata aataccacag gagatattaa aagcgatata aaaaataaaa
    12121 ataaaaaaaa tagtatttta aataatataa tagatacaat aactggttgt atgacaccta
    12181 tgataccagc ccttacagca tctgggatga taaaagttat attatctctt tgcaccactt
    12241 ttaattggct atcatcaaat tcaagtacat atagagtatt agatataata ggagatgtag
    12301 cattttactt tatgcctata atacttgcaa taaatgcagc taaaaaattt aatgttaata
    12361 catcaatagc agttatagta gtaggtgtgt ttttacatcc aaatttctct gcatgggtat
    12421 caagtgggga ccctatatca tttataggag taccaattca agatgttata tatgcagcat
    12481 ctgttatccc tgcactttta acagtatgga tgatgtcata tatagaaaaa ttcattgata
    12541 aattaacacc tagcatgtta aaaacaattt taaatccaac tttagtatta ttaataagtg
    12601 cgccaatagc attaatagta attggaccaa taggaaattt cttaggagag ggattagcta
    12661 gtataataaa tttactacaa ggaaggttag gatttataat ggtttgttta ttagcagctg
    12721 caatgccatt tatcgttatg acagggatgc atcatgcatt gactcctata ttcatatcag
    12781 catttgcaac tacaggacaa gaatcgctaa tattaatatc tcaagtttgt gctaatttag
    12841 cgcaaggtgg cgcaacatta gctgtagcat taagaagcaa agatagtaag atgaaacagt
    12901 tagcatcagc tgcatggata tcagctatca tgggtataac tgaaccagct ctttatggag
    12961 ttacattgaa acttaaaaaa cctgctatgt tagcatctat aggagcagga atcgcagggt
    13021 tatttgcagg aattactcat gtgactttat atgttccaca aaatagtata atggcagtac
    13081 ttggattatc aggggaaaag gggatttcaa atatagtaaa tggacttata gttatattta
    13141 tagcattggt tgctccattt attatgacat atgtttttgg agttgaaaaa aatgttaaat
    13201 aaagtacaga taatgtagta gaggaagtat aatattaact atttacatta atagaatttt
    13261 tattattatt gactataact tgttttgtat ttatattgat gcaaagaaat aagttaatat
    13321 taataagaat aattattaga actgacaaaa agcaacataa aagattgatg aagtatatgg
    13381 aaataaaaag ttgacaaaat atgtctgatg ttttatcata ttaattggaa ttaggtagta
    13441 attgtttaag tacaagctaa gcttattcat taataatagc agtatcctag gaaggagtat
    13501 gcccattatt atggataagc tttttttatg cttaaaagga ggataatcat gataattaat
    13561 aagatattaa acaataatgt tgtaatcaca ttagatgata atgatgaaga agttatcgtt
    13621 atgggtaaag gaattggtta tcaaaaatca aaaggcaatc taatagataa aactaaagta
    13681 aataaagtat ttagaatatc aaataaagaa atatcaaaca aactacaaga attactcaat
    13741 aatattccta tagaacacat gaaattatca agtgaaatta tagaatacgc acaaataaag
    13801 ttaaacaaga agctaaatga aagtatttac atatccttaa gtgaccatac atattctgca
    13861 attcaaagga tgaaagaagg aataaatgta aaaaatgcaa tcctttggga aattaaaaga
    13921 ttttataaag aagagtttga aattggaatg aaagcactag atattattga aaacaaaaca
    13981 ggtataaaat taccagaaga tgaggctgga tttatagcct ttcatatagt gaatgctcag
    14041 ttaagtgaag gtcatacttt ggcatctgat attacgaagt taatacaaga agtacttagc
    14101 atagttaggt atcattttag gatagaattt catgaagaat cagtgtttta ttatagattt
    14161 ataatgcatt taaagttttt tgcgcaaaga ttgcttttag atagtgcaca tgaaggtgag
    14221 acagacaaag aattactaag cattattaaa tctaaatata ataaagagtt tgaatgtgta
    14281 gttaaaatta aaaatttcat taaaaaacaa tataactaca tattaacaga tgatgagctt
    14341 atatatttaa caatacattt agctaaagta gttaaagact caaatatgta agtgaaataa
    14401 tttttcagta gtatattaag aatgattgaa aggagtgata ctaacaaaat tatacttatg
    14461 gttggatggt aacattgagt tggccaaacc ttcaaatttc aaaaaattaa tttaaacgaa
    14521 atatggagga gaaaaatggg aaaatacaaa caattagcac aagagatagt aaacaatgtt
    14581 ggtggaaaag aaaatattag tgggttagta cactgtatta caagattacg ttttacttta
    14641 aaagatgaaa gtatagcaaa tgacaatgta ttaaaaaaca tggaaggtat tgttactgta
    14701 atgaaaagtg gaggacaata tcaagtagtt ataggaaatc atgttgaagc tgtctataaa
    14761 gatgtagttg aaataattgg tttagatgat tcaagtacaa gttcagaaac taaaaaatca
    14821 ggtaatatac tagataaagg tatagatata atatcaggaa tttttcagcc agtgttagga
    14881 ataatggcag cttgtggtat gttgaaagga tttaatgcat tatttgtagc aatgggatta
    14941 tatagtgatg tatctggtgg ttatatggta ataaatgcag caggagatgc attatttaca
    15001 ttccttcctt tgttcttagg atatacttca gctaagaagt ttggattaaa accaatgttg
    15061 ggattagcac taggagctgc agtatgttat cctgctatac aaggtagcag tatatcagca
    15121 ggagcagatg tgatgtacac tttatttaaa ggaacaatgt ttgcatcacc agtatatatt
    15181 gatttctttg gactaccaat tgtatcaatt gattatactg gaacagtcgt accaattata
    15241 tttatagtgt attttgcttc taggtgtgaa aaattattta ataagtgtgt tccaaattta
    15301 gttaagtttt tctttgtgcc aatgcttaca ttattaataa cagtgcctgt tgcacttata
    15361 gttataggcc ctatagcaac atttggttct acacttattt cacaaattgt aatttcaata
    15421 agagatttta gtccactatt ggcaggtgct atagtaggat ttacttggca aattcttgtt
    15481 atttttggta tgcactgggg atttattcct gtatatataa acaatgttat gactttagga
    15541 tatgataatg ttatgatgcc attctttgcc tgtacatttg caagttcggc agttgtgttg
    15601 gcaatatttt tcaagactaa agataaaaaa ctaaaagaga tggcaatacc aaactttata
    15661 tctggtatat ttggagttac agagccagca atttatggaa tattattgcc tttaaagaaa
    15721 ccatttataa taagttgtat tgctagtggt attggaggcg ctttctatgg attctttaat
    15781 cttagaaaat ttataactgg aggaatggga atatttgaac ttccagcaat gattgaacca
    15841 gatgggggaa tgggtaactt aatagtagct ctttctggta tagctatatc aatggtcgta
    15901 gcttttgtat taactatgat tttatataaa gatgagaaag tagaagagtc taaaaaagta
    15961 agaaataagg gtaaagaaga aataaaagaa gtcaagtcta ctaaattaga aagagaaata
    16021 gtaacaagtc ctataaaagg tgaagtatta aaattaagtg atatagagga tgcagcattt
    16081 gcatctggtg tactaggtca aggggtggca ataataccta gtgatggaaa agtagttgct
    16141 ccagtagatg gggtagttac aaccttattt cctagtctac atgctatagg gattctttct
    16201 gatacaggtg ttgaagtgct tattcatatt ggattaaata ctattcaatt agagggaaga
    16261 ggttttgagg catgtataaa acaaggtgat agaattacaa aaggtcaaac tatattaaac
    16321 tttgatgttt atgcaataaa agagttgggg tatagtactg taactccaat tgttattaca
    16381 aattcatcac aatttttaga tgtagtagaa acagaaagta aaaatattga attagaagac
    16441 aatctaatta cagtcttatt ttagtaaaga ttgaggtatt agcataatct agtgctttgg
    16501 ttataatttt aggaggcttt gactatgagt tttaagaatg attttttatg gggaggagct
    16561 actgcggcca atcaatgtga aggtggatac aatgaagacg aaagaggatt ggcaaatgta
    16621 gatgtatgtc caacaggaaa agatagaaca gcagttatta cagggaaact aaaaatgttt
    16681 gattttgatg atgagcatta ttatccagct aaaactggta ttgatatgta tcataattat
    16741 aaagaagata taaagttatt tgctgaaatg ggatttaaag tatatagaat gagcattgca
    16801 tggagtcgaa tatttccaaa aggtgatgaa gaaacaccaa atgaaaaggg acttcaattt
    16861 tatgaaaata tatttaagga gtgtaaaaaa tataaaatag agcctttagt cactattaca
    16921 cactttgatt gtccaatgca tttagttaaa aagtatggtg catggcgtaa tcgaaaaatg
    16981 ataggtttct atgagaaatt atgcaatgtt atctttagaa gatataaagg attagtgaag
    17041 tactggctaa ctttcaatga aataaatatg attttacatg ctccatttat gggtgctggt
    17101 atttgctttg aagaaggtga agatgttgaa aagataaaat atcaagctgc ccatcatgag
    17161 cttgtagcta gtgcaattgc aactaaaata gcacatgaag ttgattcaaa taacttaatt
    17221 ggatgtatgt ttgcagctgg aagtgtatat ccttatagtt gtaatcctaa tgatgtatgg
    17281 gaagctacaa agttagatag agaaaattac ttctttgtgg atgtacaatc taaaggtaaa
    17341 tatcctaact atgcgttaaa gtatatggag caaaaaggta ttacaccaga aatggaacct
    17401 ggtgatattg aattattgaa taaatataca gtagatttta tttcattttc atattacaat
    17461 agccgttgtg ttagaaccga tgaaaatgca gatgatatgg ctgaaggaaa catatttaca
    17521 tctgctaaaa atccatatct ttcatacagt caatggggat ggccaattga cccattaggt
    17581 ttgagaatta cactaaatca tgtatatgat agatatgaaa agccactatt tattgtagaa
    17641 aatggattag gtgctaaaga tatagctgat gaaaatggtt atgtagaaga tgattacaga
    17701 attgattatc taagagaaca tataaaagct atgcatgatg cagtttctat agatggggtc
    17761 gatttattag gttatactac atgggcacct attgatttag taagtgctgg tacaggtgaa
    17821 atggaaaagc gttatggatt tatatatgta gatagagaca atagtggtaa tggaagtcta
    17881 agaagaatga aaaagaaaag ttttgaatgg tataagaaag taattgcttc aaatggtgaa
    17941 gatttatatt agacaagaaa tctatgttaa ataagaaatc tatattagac aagaaatcta
    18001 tgttaaataa gaactttgta ttaaataaga agagtataaa aattaataat aagtataatt
    18061 tttaactttt ttaactatag aaaatcaata tagaattatt ttacattgta ttgatgcaat
    18121 agtatgattc acaaataaaa ttttagaaaa taaaattgtt aagaagtatg ggaagtaagt
    18181 gcaatttact ttgtaataaa agatgaaaaa ggcaagctta ggttttaagc ttgtcttttt
    18241 tattatgtat aaactatgat attttaaaat tctatgaaaa atttatttaa tagagaaatt
    18301 aaaaatttaa tggtaatcaa attctttacc aatgaatata aaaaatgtct acgtgttata
    18361 atagtttaaa ctaataaacg aaaggtagat gaatgaatat gaaataccaa catataatag
    18421 aagttgacaa agaactttgc attggatgtg ggctttgtaa aaatgattgt ccagtaaaca
    18481 atataattat agaaaataaa aagtcagtaa ttaaaaaaca agattgtcta atgtgtggac
    18541 attgtgcagc aatatgtccc acaaaagcta ttaccttgac aggatttgat gaacctccta
    18601 tagaacttac aaataagcca aagctagatt cagatgaatt actaatggca attaaatcta
    18661 gaagaagtat acgtaaattt aaagataaag aagtttcttc agaaattata aagcaaatta
    18721 ttgaggcagg taggtatacc cctagtgcta aaaattcaca agatgtatca tatattgttt
    18781 tagacaataa aaagtcaatt tatgaaaacg aagcagtgaa attttttaga aaaataaaac
    18841 ctattgcaaa tatagctatt aaatattcaa aagaagttga gattgacgat aactttttct
    18901 ttaagcatgc tcctattgca ataatgataa ttacaaaaga taagattagt ggttcacttg
    18961 cagcatcaaa tatggcatta atggcagagt cttatggtct aggtgtttta tttagtggat
    19021 atttttcaga tgtagcaaat aattcgccaa aattaaaaaa gcttttaggt ctaaaacgta
    19081 gtaatcatgt tcttacaaca ttagtaattg gatacccaga tgttaaatat agacgtactg
    19141 cacagaaaga agtagcaact gttagatact tataagagag ggtggatttt atggaaaaag
    19201 aatgtcaaca aagaatgcaa gaaataacgt ctaaatttaa agaatgtcgc aaagctatct
    19261 ctgctatggg tgatgagact agacaattga ttttaattgc tcttttagag agtgatttta
    19321 atggtatacg agtgggagaa atcacaaaaa aaacacatct ttctcgtcct gctgtatctc
    19381 atcatcttaa gatattaaaa gaagcagaga ttgttaattt gcgtagagaa ggaacgaaaa
    19441 attattatta tcttgattca aaaaaatcac aatggaagtc actaacagag ctaataaatc
    19501 ttatatttgt tggaatacaa catattagtg aaaatgatat aagaaaaggt gattaaatta
    19561 tacttgattt aatacaaaaa gattgattta ggaactaaaa aattcacttt gagacactat
    19621 cttttgaact atacccattt taggagacgg ttaaaatatg taaaactgta taaaacaatg
    19681 ggtatagttc attttataat ggtttaaata ttaagaatat attattctaa atagtatctt
    19741 tctctgtttt gagttttatt tttatactca atagcttcag tggggcaacc acaaatacat
    19801 gccatacaat gagtacagtt atttttccaa actggttttt tgttttttaa attaatatta
    19861 tttaaaggac atagctctac acattttcca cagccaatgc atttatcagt ataatgaaat
    19921 cctttggcac taataattgt cttataaaaa actgtattta ttataccact tttaattgta
    19981 cctcctaagc cactaggagt aatagtttca aattcatttt cattgcgtat atcagaaata
    20041 atcctatata tttgtttatc tgcttcttta atcatttgtt ttgatgtttc tttgtctgtt
    20101 gtagaaaata aagctatata attctctggc attttaattt ctgccatacc ttttaattgc
    20161 cattccttgt atttacatag tttttgaata tagtttatgg attttgctgt atctccacca
    20221 caagtcatta caaagtaaac tctgttgctt cctagaaatt ttgtttcttt tataaaatcc
    20281 gtaactacta ttggcaatct ccatgcataa gtaggacata caaatatgaa tggtttatct
    20341 gctgatatta attcatctgt tttttcctct tttataagtt gatttagtga tatcagttca
    20401 tcatttaatt cttgtgcaat tttacgagcc acatatcggc tattaccagt tccgctaaaa
    20461 tataaaatca taataatatc tccctaacta ttttttattt attatagtaa tttattgata
    20521 tattctattc aaatgtatgt aaaatttagt agttaagaaa attataacac attagtaatt
    20581 tttatactta ttggtaaaga atttgattac cattaaattt agcaacaaga catcaactgg
    20641 acttgtatat gagaagggat aataatttgc ttatgaaaga ttataaatat aaaggttatt
    20701 ttaaaggtgt agaaatattt gataatgtaa atgaccttaa cttaaatact ttaacaacag
    20761 ttagtagatt tgtgcttgtt tttttgttta cgataactta aggaaatatg ttacctgaat
    20821 aataaattta tataataaaa gtatataaat atatatatga atgttaagat tagttgatag
    20881 aatttaaata ataaatccaa tattataaac ataggaggta tgaaaaatat gattaatgag
    20941 aatttaaaaa gtctaagaaa aatcaaccag tatacacaag aagaattagc tgaaaaactt
    21001 aatgtttcta gacaatcaat agcaaaatgg gaaagtggag aatctattcc tgatatatgt
    21061 agttgcatta aacttgcaaa attgtacaat gtcaaactag atgacttagt taatcattca
    21121 gaagaaaaaa caggtattat agtacctcct aaaggaaagt ttttctttgg agcagttgta
    21181 gttggtgaac gtggtcagat tgtcattcca aaagaagcaa gagaagtatt taatataaat
    21241 gcaggagata aattattggt acttggagat gaggaaagag gattaggaat tgttcatcaa
    21301 cgtgatttga taaattttat aggtcatgtg ggagtagtac gtaaagaaga atgatttaaa
    21361 aaaattataa aaggaggtat gaaatatgag taaaatagta ttttttagca ttcctgcata
    21421 tggtcatact aatcctacta ttgaagtagt tcgtgaatta gtggatagag gaaatgaggt
    21481 attgtattat tcttttaatg aatttaaaga taaaattgaa ggtgctggag caaaatttat
    21541 ttgttgtgat aaataccttc cagaattact ccctggagat gagaaaaaaa ttggtaagga
    21601 ttttcctgga ttaattgaga tgatagtaga tactactatt tctttagatg aaaaagtttg
    21661 tagagaactt aaagatttta atccagattg cattgtatca gattcattaa gtttttgggg
    21721 aaagttattt gcacaaaaac ttaatattcc atatgtatgc tctacaacaa cttttgcatt
    21781 taataaacat acagcaaagt tgatgaaaca aaactttata gaaattatac gtatgatttt
    21841 tggtgtaaga cgcattaata aaaaaataaa gcttttacaa agaaaagggt atgaagtaaa
    21901 aaattttatt tctatagttt ctaatgataa tgatacggat accattgtat atacatcaaa
    21961 agaatttcaa ccaatggtag aaaccttctc tagtaagtat tcatttgtag gtccatcagt
    22021 atcaaagttg attattgaac ctaaagagag aaaaagaaag ctaatatata tttcgcttgg
    22081 tacaattaat aataaaaatg ttagctttta taaaaactgt ataagtgcat ttaaagattc
    22141 tgatgttgat gtgattatgt ctgttggtag aagtactgat attaaaagtt taggaaatat
    22201 accaaataat tttgaggtca aaaatagtgt tgaacagatt gctatacttc aaaaaactga
    22261 tgtgtttgtt actcattctg ggatgaatag tgttaatgaa agtttatatt atggagtacc
    22321 tatggtatta tttcctcaac attcggagca gagaatggta gctaagagag ttgttcattt
    22381 gggagcagga attatgttaa aagaggataa gtcagaaagt attaaaaaag cagtatttca
    22441 agttataaat gacaatgaat ataaagaaaa tgcaactaaa ctatcaaaaa gcttttataa
    22501 tgcaggaggc tcaaaaaaag cagcagatgt aatattacag attatatgta atagtagaca
    22561 agttgacata taatagattt gttaaaaata tatatacata catgtaattt aatcaaagta
    22621 ctgacagtgg ggtcttttaa cctaccagtt ggggcatata tattgatgct aaatatgagg
    22681 gatgttatat tttaataaaa aagataacat ccttttttta gtgcattata tcgagtttta
    22741 aataataaat gaaggaggat taatatgaaa aaatataaag ttatttttat agtattaatt
    22801 ataggtatta taagtgtaac agggtttgtt gtatataaaa actgcattaa accatggaaa
    22861 gatgctgaaa catatattga taagtatatg gtaaaacaag atatttcaaa agataatata
    22921 aaaagtatta caaaagaaaa agccaagaag gcaagttacg aaggaatact atacaaagtg
    22981 tattacaaag atgaccctcg atatgagtat caatattttt atagtgataa ttattatgct
    23041 ctatatgtaa ataaagtaat gttacaaatt tatgatatgg aaaataataa taaactttta
    23101 agaagtaatg aggaattaaa aagtgtaaag tatccactaa tatatcttaa atataagcca
    23161 gataaatgat ttatgacaaa atagaatgat ttttattaaa atttatttaa aaatatcact
    23221 agagcgttta aataaaacta aatttaagta tttatatatt agtatatctt actagtgttt
    23281 aaacaaaatt aaatttaag
//
LOCUS       DAEPHU010000066        23045 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 01A10CD0081
            SAMN05941466-rid12468953.denovo.066, whole genome shotgun sequence.
ACCESSION   DAEPHU010000066 DAEPHU010000000
VERSION     DAEPHU010000066.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941466
            Sequence Read Archive: SRR6291087
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 23045)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23045)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068158.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 22:43:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,892
            CDSs (total)                      :: 3,805
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 87
            rRNAs                             :: 8, 1, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 55
            CDSs (without protein)            :: 55
            Pseudo Genes (ambiguous residues) :: 0 of 55
            Pseudo Genes (frameshifted)       :: 21 of 55
            Pseudo Genes (incomplete)         :: 28 of 55
            Pseudo Genes (internal stop)      :: 16 of 55
            Pseudo Genes (multiple problems)  :: 8 of 55
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23045
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941466-rid12468953.denovo.066"
                     /strain="01A10CD0081"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            223..1059
                     /locus_tag="KR231_002760"
     CDS             223..1059
                     /locus_tag="KR231_002760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HBH0005122.1"
                     /translation="MNIKKIFNNNVVVSSLEDGTEIIVTGAGVGFKKKVGDLIDENLI
                     SKKYFVQDDQRDKYNQILNKTSIEYFKISEEIIEKANEVLNTQVNDSIILALTSHIEF
                     AVQREKQGIKLPNLILNETKQLYREEFEFGLWAIDEIEKRIGIKLPEDEAGYIAIHII
                     NGLENSQKDEGINILEFSKQVIQIIEEVHGFKLDVNSLNYTRLITHLKFFVQRILRKE
                     TYNDSDIEDMYKLVNKNYNKPKVCTEEIAALVLDRFEYKISKEEELYLMIHINKITNS
                     GC"
     gene            1412..2989
                     /locus_tag="KR231_002761"
     CDS             1412..2989
                     /locus_tag="KR231_002761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HBH0005123.1"
                     /translation="MKKNKLGLWNFFQMLGKTFMFPIALLSVSGMMLGLGAGFTDPKM
                     IEMVPFLGNEYVNLVLNFMLTIGLFAFNNLGALFAMAIPLGLLKKEKEFGAFSGLVGF
                     IAMHIGTNFYLTRADLLVPAEQMSTNGQAMIMGIQTYNTSVLGGIVAGLIVYAIYDKV
                     SNLKIPESLGFYSGPRLVPIVSLIVMSIVGLLIPIVWPPFFNAFQSLGRWISSAGPLG
                     YFSYAVAERVTIPFGLNHLVTSVFRFTPIGGTAVIDGETYFGTLNMFMAYVENNQIIP
                     LDLAGKMEQGKLMIQYGLAGAALAIYRTAKPENRKALKGLLISGVLTVIIGGISEPIE
                     FLFLFISPALFAFHTFMNGIANMVLPYLGVLMGFTGDLIAFISFGVLRGTATGWPIAV
                     LVAVLYFAIYYFVFKWAIIKFNIKTPGREDKEIKVSEGNGSDFKNLSTYKGQQMISAL
                     GGQSNILSLDNCVTRLRLKLQDVSLINEDAIKEAGGIAVVKLDEHTIQVIIGTQVYSL
                     RKQMDKAMEGHLEACND"
     gene            2982..4166
                     /locus_tag="KR231_002762"
     CDS             2982..4166
                     /locus_tag="KR231_002762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PatB family C-S lyase"
                     /protein_id="HBH0005124.1"
                     /translation="MINFDKKVDRLGTYCTQWDYVEDRFGKKDLLPFTISDMDLEFPF
                     EITEVLQERLNHRVLGYSRWKHDDFRNSVTNWYIKRFNCSVDSNWIYYSPSVMYSISK
                     LIEMLSNEGDGILINTPAYNAFYDVIINNNRNIIKSHLVNRNGFYSIDFNDFEKKCKK
                     SKIFILCNPHNPTGRVWSELELVKMIGICKNNDVKIISDDIHMDIVYDNRMTPILNVA
                     KDYLDSVFICTSASKSFNIPALTGSYVIIPNEGIRNKFENITRYRDFVNSPAILAILA
                     TMVCYDDCEYWLDELLKYLKENLKYTIDYIKDNLEPLKLVMPEGCYFAWIDFSELKIS
                     GEKFQKLLMDIGEVAIMSGSVYGEEGEFYLRLNVACSREKLEDGLNRIKKTMDYIAKR
                     IL"
     gene            4184..4783
                     /locus_tag="KR231_002763"
     CDS             4184..4783
                     /locus_tag="KR231_002763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HBH0005125.1"
                     /translation="MGYLKTMVDVMTTEMNAIRCLIDEAGIEYESIVSEIANCEGKVI
                     FMGVGKSAHIGKKLAATFASTGTPSFFVHATEAVHGDLGMIESKDITILISNSGNSME
                     VVNCIKYIKAIGSKTIAFTSNRNSVLAKECDYALIYPAKDEADHLNLAPTTSSTITLV
                     LGDSIACALSKSSNFGSSDFYKYHPGGSLGEKLKTANNG"
     gene            4807..5277
                     /locus_tag="KR231_002764"
     CDS             4807..5277
                     /locus_tag="KR231_002764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HBH0005126.1"
                     /translation="MFKMFKKKSIKSPISGKVIELSKIQDGVFSQKIMGEGVAIDSTG
                     DIVYAPINGKIVVVAETKHAFVIELENGMELLIHVGLDTVNLKGEGFEVLVSMGEQVK
                     EGTPMLKINRPLIESKGISLITPVTITNHSEYNMNTCNVGNSVEGGKDTVIEFK"
     gene            5649..6395
                     /locus_tag="KR231_002765"
     CDS             5649..6395
                     /locus_tag="KR231_002765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2087 domain-containing protein"
                     /protein_id="HBH0005127.1"
                     /translation="MKIENLSIDDIKRGYIFNDDLNCYSCIKCTKTYEVGEIYKIGNR
                     FFEASKAIELHMELEHSDYLEQLLNSDSKYNTLTENQKQLFQLFISDLPDKEIAKQVG
                     VSTSTIRHQKFIFREKAKQAKLYLALYESVFEDKSNKSSTIIPIHEHARMVDERYVVT
                     EEERKHILDTSFESMNPLKLKVFSSKEKKKVVILSKILEQFERGKKYSEKEVNQILES
                     IYDDFATIRRYLIEYGFMSRNKECTKYWLT"
     gene            6456..7130
                     /locus_tag="KR231_002766"
     CDS             6456..7130
                     /locus_tag="KR231_002766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="epoxyqueuosine reductase"
                     /protein_id="HBH0005128.1"
                     /translation="MNDELKSILYNKGVDIVRFVDISEFPINQTQGFSKAILFCIGLS
                     KKFITDIYNNLPTDSDEFLEKEEKVEELADWISKYIQNKGYRAYSQSEKNNLEHGYFE
                     KAYINPEMQSGISPLPHKTIANISGIGFMGKNNLFVTEEYGCAFSMCTVLTDAPISVE
                     RYPLIDSKCMDCNVCVENCPAKAIHGNEWTLPGKRESIIDVSKCFCVLRCMMSCPWSL
                     RYANQK"
     gene            7499..8845
                     /locus_tag="KR231_002767"
     CDS             7499..8845
                     /locus_tag="KR231_002767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 55 protein"
                     /protein_id="HBH0005129.1"
                     /translation="MEIETKTPDWINVLELNSKIDITGKYDVSNMIQNIVSDKSLEGS
                     IIYFPKGNYLFEKGIKISQQITLQGDSYYGGGNQVSNLDKKQSIIGTTNFITRGVSNM
                     SIITLSGTSQCIKNINFYYDSHDIEKIPPKNVSAITEYGETQGLSHFEHLFISGFSGI
                     GIEIPYYSTGNDITVSSCGLGMRLGEKSMLSSSKIYECKNGMEITTGVSLNNVRIEEI
                     KEIGINNKGFGFNLIMNLMVDQCGYCGFMFEKMCYSQITARITRCGQYYKSVDYNAYE
                     NMEDRKEEAYSIFYGDILENCNIVLMNSNIDTLENDSLDEHKIYVIKANETNNVMLTC
                     YAEADNFIQCAKGNLLLENGENTYKFYNGEICSVGGVQISDIDEKDLIKIIENTLYID
                     DKGKYLMVPRLKKNTVIYSVLDSTEEINKLHGGIWEQIDVKVLAGESMYYYKKIKD"
     gene            8872..10272
                     /locus_tag="KR231_002768"
     CDS             8872..10272
                     /locus_tag="KR231_002768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0005130.1"
                     /translation="MEESIIIKDISGWINVLDYGICNDETKDVSFKLQEIMDAVPEDS
                     IIYFPKGKYLFESGVKIKKRLTLCGDSYILANVPKNTAGVTQFTFKGKKNPKSENIAI
                     ITAKSVRHCIKSICFYSDSCDRDMTSNHEPPTDGKPRFHHNVIINYRNISAIVCEDKQ
                     GESGHYKNLSFSGFSGIALDMPNNSTANDITIFTSGLGISTGENSTIANSKVWGCVDG
                     MIISTGTFINGMRVEEIKKVGIKNIGRGLNFITNITIDQCGYCGVWFDSISNVQISGN
                     ITRCGQYYYDVSYDNYLMLDNRVKEAYSLFYGNLLESSNIVLSNTNKDNWEDFKEDKH
                     KVYLVEALETKNVLLTCNIDATDWIVKSEKGNLTYNNMRQTVIFYDGKLSSINGIGIS
                     DEDYGDKVKIKKGNIYINSKDKDIKMHKPEVGDIMSTIIKDKSILSAHYGGTWEKIGE
                     KIEFGITVHYYKLIEK"
     gene            10482..11918
                     /locus_tag="KR231_002769"
     CDS             10482..11918
                     /locus_tag="KR231_002769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 55 protein"
                     /protein_id="HBH0005131.1"
                     /translation="MEGRTGIKDGRWINVVERGIKNDGSYNVGPALQDIIDEIETDFC
                     VLYFPKGKYLFTSGVKINKEIVLQGDSNSSTGTTQFITRGVENMSIITLTGKKQCIKN
                     INFYSDSCEIQVNKEPPTKGNPKYHYEMIINKNEKNVEMNNVSAILYDNSKNMIKGLG
                     HYENIYISGFSGTGIRIPYYSIVNDITVSSCGLGIDTGIDTIISNSRISKCQNGMRIR
                     TGTSINNVRIEKIQKVGLISSQVKGYEGYGSYKINNITIDQCGYCGFSFDSMKDSYFS
                     GIIRRCGQYYYNTDYDTYLSIKDRVEEAYSLFYGNYFTECNIDLVSDNKDNWDDGLEY
                     KHKVYVFKTLQIPKLTLRCNIDAYDYIVKSVHGGGNLMLKNNFNNYIFIDSSNPEVIN
                     GINFNYQKNGNLLRLNNGKLSYKNGKEETAIFRPNYGLIVASTDSECEQIETSYGGKW
                     EKLGSEVIGEETVYYYKHHEPDKTNQIQ"
     gene            12262..13206
                     /locus_tag="KR231_002770"
     CDS             12262..13206
                     /locus_tag="KR231_002770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1848 domain-containing protein"
                     /protein_id="HBH0005132.1"
                     /translation="MIVSVSRRTDIPAFYSKWFFNRLKEGFVYVINPMNPKQVSKIEL
                     NPHTVDCFVFWTKDVTPMLYDLNKLKDYKYYFHYTITSYGKEVETCILDKRKVIDSFK
                     ELSRKIGKERVILRYDPIFLSEKYTVDYHIKAFASLCNQLDGFTEKCIISFIDLYKKT
                     KFNTKALHIKPIEITEIETLSKEISKIAHKHGITLEMCSEEYNLSKFGIGKSKCIDDR
                     LISKIIGCEVEVKKDSTQRDICGCVKSVDIGQYNTCRHYCLYCYANFNYAKVEENCRL
                     YKEDNKLLIDTLRDDAKISIRDMKTIKVDKNKQISIFD"
     gene            13375..14307
                     /locus_tag="KR231_002771"
     CDS             13375..14307
                     /locus_tag="KR231_002771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TDT family transporter"
                     /protein_id="HBH0005133.1"
                     /translation="MNLLKKYPIPIASLILSIFTLGNLLQSYSESLRNVIGFIGFILY
                     AIYIVKIILLRKGVKEQLENTLISSTFPTITMATMIFATYIKPLSLELSIMIWSIGIV
                     GHLVLIVLFSKKFLVKFSIKTVFPSWYIVYVGIVAASVTAPAFNQLLIGKIAFWIGFV
                     SYIVLIPVILKRVWIIKEMPEPSLPSIAILAAPGSLLLSGYINSFSDKNNVVLYLLFI
                     LSIVFYIIVLGYLPKLLRLPFYPSFAAFTFPMAISAMGMKLMNGYLTKSGHFISWISY
                     ASKLEEIIATVIILYVLVLFIIYLSKSETTSKAK"
     gene            14412..14879
                     /locus_tag="KR231_002772"
     CDS             14412..14879
                     /locus_tag="KR231_002772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C_GCAxxG_C_C family protein"
                     /protein_id="HBH0005134.1"
                     /translation="MKTKEEYLKEVRNISEEYFRKGEFFCSEAVLQTINDALGQPLSP
                     EITKLASGFPIGLGKAQCLCGAISGGEMALGIVYGRVHGEAMNPKMFEHAKGLHDYIK
                     KEYGATCCRAITKKWDGDNFMSPERKEHCIKITGQVTEWVADKLIEDEKLNIK"
     gene            complement(15123..15977)
                     /locus_tag="KR231_002773"
     CDS             complement(15123..15977)
                     /locus_tag="KR231_002773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009912760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose uptake protein"
                     /protein_id="HBH0005135.1"
                     /translation="MLTIIIALLPVMGWGLMPIVANLKKSSPHEQLLGTSISAFIFST
                     IITLVIHPEITFFSFCISMISGIFWSLGQLMQFKAIQIASVSKVMPISNGSQLTFTTL
                     LAVILFNEWTSSKMLLIGSLSILCIILGILLTNYQTKKSTDKNMLKCVGVVLLSSLFL
                     SLYVVTNQIFLIEGYRIILPQSVGMLITSSIIVKYFSKEIVYRENVLFNLITGILWSI
                     ANLGMFITTNTLGVTISFSISQSCVIVATLGGIIFFKEKKNKKEWLAIFIGIILIMSG
                     VFMLSIIK"
     gene            16143..18107
                     /locus_tag="KR231_002774"
     CDS             16143..18107
                     /locus_tag="KR231_002774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HBH0005136.1"
                     /translation="MLTDMIQNREIKIIKFLLKEGHTTVKAIADDLDVSEKTVSKSLK
                     EVEAVLKKIGLSLIRKPKIGVYIDGDLKKILPYLDNKGSQIPTTREERVIYIYSVLLK
                     SNDYITIQQLSDELYISRGTIERDLAEVEKLLKNEGISIYKKPSKGIKLNISERDKRQ
                     LTAKFIHKFWSRNWYIKQEQESFYQAFEKIQADVNGIFSEDDLSIIIDILRNFSRERK
                     FEFSDYEFQSLVIHLAIAVERIRKGEYIEESLYTGNIENNQMSNTNYLAKQLEEKFSI
                     LLPKSEIGYINLHLVASDQHRDTNELKNTSTNPCETSTNNISNLREIIKNTLYETAYD
                     KDLIDGLTSHVHSSINRLKYGLSIKNPYVNTIKQNFSLSFEQALDLKKVIEFIYDIRI
                     NDDECAYIALHFEAFRERMKELPQNIRVILVCSTGLGSSRLLSARIKKYFPMIKIEKV
                     LSVQELVSSKIDADLVISTIYLELETIPTIVVSPILNESDIRTLERNIQNVSSCTSKK
                     YKSFRNLIFEENILLNIEASNYEDAIKYITDNLIKKGFAKEGIAKSAIERENLSYTSF
                     QSIATPHANPSYIKKSNISVATLKNPITWGNEKVEVIFFISLENDKNLELDEIYEVFY
                     DFIDNKKNINDILSATSTKEVYDLLVEESI"
     gene            18107..18568
                     /locus_tag="KR231_002775"
     CDS             18107..18568
                     /locus_tag="KR231_002775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBH0005137.1"
                     /translation="MKISDVLKKEQIVFNLDTNTKEETIKKLSSIFVENGIVDNEEEY
                     VKSVLEREEHSTTGIGNGIAIPHGKSNAVKKSSIIFAKTKHKIEWDALDEKPVDSIFL
                     LAISNIDKDSNHLVLLSKLATKLMDDDNVDALKLANSEQEIINIFSEEGEM"
     gene            18571..18891
                     /locus_tag="KR231_002776"
     CDS             18571..18891
                     /locus_tag="KR231_002776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIB"
                     /protein_id="HBH0005138.1"
                     /translation="MKRKIIAVTACATGVAHTYMAAQALKKASKKMGHLIKVETQGAT
                     GIDNELTTKDAQIAEVVIFAVDTKVRNAERFEGKEILEVPVNAPIKDAEKVINDALKL
                     IDTK"
     gene            18907..20007
                     /locus_tag="KR231_002777"
     CDS             18907..20007
                     /locus_tag="KR231_002777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIC"
                     /protein_id="HBH0005139.1"
                     /translation="MLKKIVSELKKHVLTGISYMIPLVIAGAMIMAISRVGGSFYNIP
                     DIWDAKYAESASSIVRLLHDLDGFGGTALGLMFPVIAAFIGFSIADKLAIVPGLVGGM
                     IAKDIGAGFLGALAVGLIAGYTCLFIKNHVKLPKSAASIVPIFIVPVFGTLITVVLIN
                     YVIGIPFATLNTGLENWLNGLSGTNQILMAAIIGAMMAVDLGGPVNKAALTTSLALLT
                     SGIYAPNTAAMVGIVIPPLGLGLATILAKQKYNKQLREAGKSSLIMGLIGVSEGAIPF
                     AVESPLKVIPSCVIGTAIASAMAVGLGSVNATPISGFYGWFTVENWPMYVLSIAVGTV
                     IVAGLVIVLRGNPVIEDDEFEDDDFDEAEWES"
     gene            20127..22727
                     /locus_tag="KR231_002778"
     CDS             20127..22727
                     /locus_tag="KR231_002778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-mannosidase"
                     /protein_id="HBH0005140.1"
                     /translation="MIKAHIVNHTHWDREWYFTSGDALVLSEQLFTDVIDELERNPDV
                     SFVLDGQLSILDDYVQLHKEKIEIIKKLIKEDRLHIGPWFTQTDAFFARGESILRNLM
                     IGIFESKKYGKYMKIGYLPDTFGFNAQMPILLKHVGLDNIFFWRGIHLGKQVQSPYFK
                     WKSLNGESYIYAVNMPHGYGTGMLLEPSLKYVNGRLDPAIDFIKSYTDVDEVLIPSGN
                     DQLNIIGDFKNKIKAINDIGKYSYITSSYQEFLKYIKSIESLESYRGEFREPVLARIH
                     KSIGSSRMDIKLACDKLENKLIKRIEPLLVIAKKSKIEISNQLLINTWKKLLEGQAHD
                     SLAGCVTDTVTDDILHRIREANEICDSIENTIVKKISEGLKLSKNDILVFNTEAKRFN
                     GYKEIQVVSDSKNIYFKDNLDATIIEETYVKPRENVLEETPAGNIFIEEPGYYILKVR
                     INVQLPALGYKVVSFELSDKEMVSLDKSNDTFISNDNYKIIYEDGSLNLQLKDGTYIS
                     NFLTLKDSGNAGDTYDFSPLKNDENIKLSFDKVYTEKALGYEKMVVKGTTLLPLTLED
                     RKNKYLNGKLNVKVSIVLSKENPLMDVKLCVDNTIYNHRLRVHIKTDIKDNKNIASLP
                     FGYITRKNGVLDNWEDIYSEMPIDLEPLESNITLTNQNRSCTVFTRGIKEYQHIEDEI
                     ALTLLATTDELGKPDLLYRPGRASGDTTKKGHIRIKTDKAQMLKELEFSFAIYMDSKS
                     FDELEIANLTHNYLRECVNYQLQDYNFFLYHIDNKIQKSIVNKTVSRELEIISLPENY
                     LISACYPSYYSKDKFIIRVENPSSNRMILDEQIFKNRNGKIVNAIEDVEEEQVYEIAP
                     FDVISILLDL"
BASE COUNT         9062 a         2355 c         4058 g         7570 t
ORIGIN      
        1 ttaaataatt aaatatacat aagaaataat taaatatctt tcaatgaaaa tatgataaaa
       61 tatgacaaat taattgatga caataaaaaa tattttgtta ttgtagtatt atagggtaaa
      121 ttgcaaaata tatacgaaag taaaatttta aatattgaca ttaaattaaa tatactatac
      181 tatgtaagtg tgatgagaga atttttttag aggggattta tagtgaatat aaaaaagata
      241 tttaataaca atgtagtagt aagctcccta gaagatggca cagaaataat tgtcactggt
      301 gctggagtag gatttaagaa aaaagtaggc gatttgatag atgaaaattt gatttctaag
      361 aaatattttg ttcaagacga tcaaagggac aaatacaatc aaatacttaa taagacctct
      421 attgaatact ttaaaatttc agaagaaatt atagaaaagg ctaatgaagt tttaaatact
      481 caagtgaatg attcaataat attagcctta actagtcaca tagaatttgc tgtccaaaga
      541 gaaaaacaag gtataaaatt accaaactta atattgaatg agacaaaaca actttatagg
      601 gaagaatttg aatttggatt atgggcaatt gatgaaattg aaaaaaggat aggaataaaa
      661 ttgcctgaag atgaagcagg atatattgct attcacataa tcaatggttt ggaaaattct
      721 caaaaagatg aaggtattaa tatactagag ttttcaaaac aagttattca gataattgaa
      781 gaagtacatg gatttaaatt ggatgtaaat tcattaaatt atactagact tataactcac
      841 ttaaagtttt ttgttcaaag gattctccga aaagaaactt acaatgatag tgatattgaa
      901 gatatgtata agttagtgaa taaaaattac aataaaccta aagtgtgtac tgaagaaatt
      961 gcagcattgg tattagacag atttgaatat aagattagta aagaagaaga attatattta
     1021 atgattcaca taaataaaat aacaaacagt ggttgttagg attgtaactg ataaagcagg
     1081 caaaacctaa gtcattgagc ttaactatta gattaagttt tttgatttag gtttttttat
     1141 tagatacaat caaaatacag acagtgactt ttaggattgt aactggttaa gcaggcaaaa
     1201 cctaaatcat tgaatttaac tattaggtta agttttttga tttaggtttt tttattagat
     1261 acaatcaaat acagacagtg acttttagga ttgtaactgg ttgagcaggc aaaacctaaa
     1321 tcattaaact taattattaa attaagtttt ttgatttagg tttttctata aatttgatta
     1381 tgtttttaga taaaaatagg aggggaaaat tatgaaaaaa aataagttag gtttatggaa
     1441 cttcttccaa atgttaggaa aaacgtttat gttcccaata gcactactta gtgtttctgg
     1501 gatgatgcta ggacttgggg caggttttac agaccctaag atgattgaaa tggttccatt
     1561 tttagggaat gaatatgtta acttagtttt aaacttcatg ttaacaatag gattatttgc
     1621 atttaacaac ttgggagcat tatttgcaat ggcaattcca ctaggattat taaaaaaaga
     1681 aaaagagttt ggtgcttttt caggattagt aggatttata gcaatgcata taggtacaaa
     1741 tttttattta acaagagctg atttgttagt accagcagaa cagatgtcaa ctaatggtca
     1801 agctatgatt atgggtatac aaacatataa tacaagtgtt ttaggtggta ttgtagcagg
     1861 attaattgtt tatgcaatat atgataaagt tagtaattta aagataccag aatcattagg
     1921 attctacagt ggaccaagat tagttccaat tgttagttta atagttatga gtatagttgg
     1981 attattaata cctattgttt ggccaccatt tttcaatgca ttccaaagtt taggaagatg
     2041 gatttcttca gcaggaccat taggatattt ttcatatgca gtggcagaaa gagttacaat
     2101 tccatttgga ctaaatcatc ttgtaacatc tgtattccgt tttacaccaa taggtggaac
     2161 tgctgttatt gatggagaaa cgtactttgg tacattgaac atgtttatgg catatgtaga
     2221 aaataatcag attatacctc ttgatttagc tggtaaaatg gaacaaggta aattgatgat
     2281 tcaatatgga ttagctggtg ctgcattggc tatctaccgt acagcaaaac cagaaaatag
     2341 aaaggcactt aaaggacttt taatatcagg agtgttgaca gttattatag gtggtataag
     2401 tgaaccaata gagtttctat tcttattcat atcaccagca ttatttgctt tccatacatt
     2461 tatgaatggt atagcaaaca tggtacttcc atacttaggc gtgttgatgg gattcacagg
     2521 agatttaatt gcatttataa gttttggtgt gttaagagga acagctacag gatggccaat
     2581 agcagtatta gtagcagttt tatattttgc aatatactat tttgtattta agtgggcaat
     2641 tattaagttt aatataaaga ccccaggacg tgaggataaa gaaataaaag tatctgaagg
     2701 aaatggttca gatttcaaaa atttgtctac atataaagga caacaaatga tatctgcttt
     2761 aggtggtcaa tctaatatat tatcactaga taattgtgta actagattgc gtttaaaact
     2821 acaagatgta tcattaataa atgaggatgc aattaaagag gctggtggta tagcagttgt
     2881 taaattagat gagcatacaa tacaagtaat tataggaact caagtgtatt ctttaagaaa
     2941 gcagatggat aaagctatgg aaggtcattt ggaggcatgt aatgattaat tttgataaaa
     3001 aagtagaccg attgggtaca tattgtaccc agtgggacta tgtagaagat agatttggta
     3061 agaaggattt gcttcctttt acaatttcag atatggattt agagtttcca tttgaaataa
     3121 cagaggtgtt gcaggaaagg ttaaatcata gagttttggg atacagtaga tggaaacatg
     3181 atgattttag aaattcagtt acgaattggt atattaaaag atttaattgt agcgttgata
     3241 gtaactggat atattatagt ccaagtgtaa tgtattcaat tagcaaactt attgagatgt
     3301 taagtaatga aggagatgga atccttataa atactcctgc atacaatgct ttttatgatg
     3361 tgataataaa taacaatcgt aatattataa agtcacatct tgtaaatagg aatggattct
     3421 attcaattga ttttaatgat tttgagaaaa agtgtaaaaa atctaagata tttattttat
     3481 gtaatcctca caatccaact ggtagagtat ggagtgagtt agaacttgtt aagatgatag
     3541 gaatttgtaa gaataatgat gtcaagataa tatcagatga tatacacatg gatattgtat
     3601 atgacaatag aatgacacct atcttaaatg ttgcaaagga ctatttagat tctgtattca
     3661 tttgtacatc agcgtctaaa tctttcaata taccagcatt gactgggtca tatgtgatta
     3721 taccaaatga aggtattaga aataaatttg aaaatatcac tagataccgt gattttgtaa
     3781 attcgccagc aattctagca atattagcta caatggtctg ttatgatgac tgcgaatatt
     3841 ggttagatga actattaaaa taccttaaag agaatcttaa atatacgatt gattatataa
     3901 aagataattt agaaccattg aaattggtca tgccagaagg ctgttacttt gcttggatag
     3961 atttttccga acttaaaata agtggtgaga aattccaaaa attattgatg gatattggag
     4021 aagttgctat tatgtcgggg tctgtatatg gtgaagaagg tgagttttat ttaaggttaa
     4081 atgtggcatg ttcaagagaa aaacttgaag atggtttaaa taggattaaa aaaactatgg
     4141 attatattgc aaaaagaatt ttatagtagg aagggagata gttatgggat atttaaaaac
     4201 aatggttgat gttatgacta ctgaaatgaa tgccataaga tgtttaatag atgaagcagg
     4261 aatagaatat gaaagtatag ttagtgaaat tgcaaattgt gaaggcaaag taatttttat
     4321 gggtgtagga aaatctgcac atataggtaa gaaattggca gctacatttg ctagtactgg
     4381 tacacctagc ttttttgtac atgcaacaga ggcagtgcat ggagatttag gaatgattga
     4441 aagtaaggat attacaattt taatatcaaa tagtggaaat tctatggaag tggtaaactg
     4501 tataaaatat attaaagcaa taggttctaa gacaattgca tttacttcaa acagaaattc
     4561 agtactggca aaagagtgtg attatgcttt aatatatcct gcaaaggatg aagcagacca
     4621 tttaaatcta gcaccaacaa catcatctac aattactttg gttttaggag attctattgc
     4681 atgtgcatta tctaagagta gtaattttgg ttcttcagat ttttataagt accatccagg
     4741 aggaagttta ggtgagaagt taaaaacagc taacaatgga taaaagcaaa aaggagagta
     4801 gtttttatgt tcaaaatgtt taaaaaaaaa tcaataaaat cacccatatc aggaaaagta
     4861 atagagttat ctaaaataca agatggtgta ttttctcaaa aaattatggg agagggtgta
     4921 gctatagatt ctacaggaga cattgtatat gctccaatca atggaaagat agtagtagta
     4981 gcagagacta aacatgcatt tgtaatagaa ttagaaaatg ggatggaact tcttattcat
     5041 gttggtttag atactgtaaa tttaaaaggc gaaggttttg aggtattggt gagtatggga
     5101 gaacaagtga aggaaggaac accaatgttg aaaattaacc gtcctttgat tgaatcaaag
     5161 ggtatatcac ttattactcc agttacaata actaatcatt cagagtacaa tatgaataca
     5221 tgtaatgtag gcaatagtgt tgaaggtggg aaagatactg taattgagtt taaataaaga
     5281 actaaaatac aaggttaata tttataaata cctataaact tatgttttat aagattgatt
     5341 gtatagattt gttgtataga tttgttgtat aaaaaagaac tctttaatta taaattaagg
     5401 agttcttttt tattttgtaa atattgttta gatttatata gaaaaacact tagtaataaa
     5461 tagaataaat aagtatttat atagctaaaa atctaaatag ttttgtttaa atatattttt
     5521 atattttgta atttcaaatt aataaataat tagatttaat aaacaaaaaa taaaaatgtt
     5581 gattatatta ataaacttta atataatata tttatgaaaa atgtaaactg tgaaatggag
     5641 gtagtaacat gaaaattgaa aatctttcta ttgatgatat taaacgaggc tatatattta
     5701 atgatgattt aaattgttat agttgcatta aatgtacaaa aacatatgag gtaggagaaa
     5761 tatataaaat aggtaataga ttctttgaag cttcaaaagc tattgaactt catatggaat
     5821 tagaacatag tgattattta gagcaattgc ttaatagtga ttcaaaatac aacacattga
     5881 ctgaaaatca aaaacaatta tttcaattat ttattagtga tttaccagat aaggagatag
     5941 caaaacaggt tggagtatcc acatctacta tacgccatca aaaatttatt ttcagagaaa
     6001 aagcaaaaca ggctaagctc tatttagcac tatatgaatc tgtatttgaa gataaatcta
     6061 ataaaagtag tactataata ccaatccatg aacatgctcg aatggtagat gaaagatatg
     6121 tagtaactga agaagagaga aaacacattt tggatacatc atttgaaagt atgaatcctt
     6181 taaaattaaa agtattttct tcaaaagaaa agaaaaaggt cgtaatttta tctaagattt
     6241 tggaacaatt tgaacgtggg aagaaatatt cagaaaagga agttaatcag attttagaat
     6301 ctatatatga tgattttgca acaattagaa gatatctaat tgagtatggt tttatgagta
     6361 gaaataaaga atgtacaaaa tattggttaa cataattaaa ataataaatt ttactaatgt
     6421 gtaatgttat ttttatctag ggggaggagt caaatatgaa tgatgaatta aaatctattt
     6481 tatacaataa aggtgtagac attgttcgct ttgttgatat atctgaattt ccaataaatc
     6541 aaacacaagg tttttctaaa gcaattttat tttgtatagg gttatcaaaa aaatttatta
     6601 cagatatata caataactta cctacagata gtgatgagtt tttggaaaaa gaggagaaag
     6661 tagaagaatt agctgactgg atttcaaaat atattcaaaa taaaggatat agagcatatt
     6721 ctcaatcgga gaaaaacaat ctagaacatg gatattttga aaaagcctat attaatccag
     6781 aaatgcaatc agggattagt cctttaccac ataagacaat agcaaatatt agtggcattg
     6841 gatttatggg aaaaaataat ttgtttgtaa cagaggaata tggatgtgct tttagcatgt
     6901 gtacagtact tacagatgct ccaatttctg ttgaaagata tcctttgatt gattcaaaat
     6961 gtatggattg caatgtttgt gtagagaact gtcctgcaaa agctatacat ggaaatgaat
     7021 ggactttacc tggaaaaaga gaatctatta ttgatgtttc aaagtgtttt tgtgtattga
     7081 ggtgtatgat gagttgccca tggtcattaa gatatgcaaa tcaaaaataa ctttactaga
     7141 gaaggtatta aattgaatat tataaaattt ttaaaatgta agattatata agatttctca
     7201 aaataaaaat ttgtatagaa cactcagaaa tgagtgtttt tttattggga ttaaattata
     7261 ttgatacaaa gcttaactat tttaatcatt atataaaatt tgtattaaaa aattaagaat
     7321 aacttggtaa tagtgaaaat ataatgagat tataattgat ttataatata actataatga
     7381 tattgtaaaa atgaaaattg tcctctcaaa attcccaaag agagtaaaag tcacttcagt
     7441 tatagtcaaa aaaatttttc tgtgaaaaga atttagattt gaaaaggagg aattaatcat
     7501 ggaaattgaa actaaaactc cagattggat taatgtacta gaattaaaca gtaaaataga
     7561 tattactggg aaatatgatg taagtaatat gatacaaaat attgtctctg ataagtcact
     7621 agaaggttcc attatatatt ttccaaaagg taattactta tttgagaaag gtattaaaat
     7681 tagtcaacaa ataacacttc aaggagattc ttattatgga ggaggtaatc aagtatcaaa
     7741 tttagataaa aaacaatcaa tcataggaac aaccaatttt ataacccgag gagtttctaa
     7801 tatgagtatt attacattgt caggaacaag tcaatgtatc aaaaatatta atttttatta
     7861 tgatagtcat gatatagaga aaataccgcc taaaaatgta tctgctatta cagaatatgg
     7921 agaaacacaa ggactatctc attttgaaca tctgtttatt tctggatttt cagggatagg
     7981 aattgaaatt ccatactatt caactggtaa tgatattact gttagttcat gtggtcttgg
     8041 tatgaggctt ggagagaagt caatgctttc tagtagcaag atttacgaat gtaaaaatgg
     8101 aatggagatt actactggtg ttagcttaaa taatgtgaga atagaagaaa taaaagaaat
     8161 aggtattaat aataaaggat ttggttttaa cctgattatg aatcttatgg tcgaccaatg
     8221 tggatattgt ggatttatgt ttgaaaaaat gtgctatagc cagataactg ccagaattac
     8281 tagatgcggt cagtattata aaagtgttga ttataatgct tatgagaata tggaagatag
     8341 gaaagaagaa gcttattcca ttttttatgg agatatttta gaaaattgca atattgtatt
     8401 gatgaatagt aatattgata ccttggaaaa tgattcactt gatgaacata agatatatgt
     8461 aatcaaggca aatgaaacaa acaatgtaat gctaacatgt tatgctgaag cagataactt
     8521 tatacaatgt gcaaagggca acttgctgtt agaaaatggt gaaaatactt ataaatttta
     8581 taatggtgag atttgttctg taggaggtgt tcaaatttct gatatagatg aaaaagattt
     8641 aatcaaaata atagagaaca ctttgtatat agatgataaa ggtaagtatt taatggttcc
     8701 tagattaaaa aagaatactg taatatattc agtactagat tctacagaag aaataaataa
     8761 attacatggt ggaatatggg aacagattga tgtaaaagta ttagctgggg aatccatgta
     8821 ctattataaa aagataaaag attaaattat caaactagga ggtagtgatt aatggaagag
     8881 tctataataa ttaaagatat aagtggctgg attaatgtcc ttgattatgg aatttgtaat
     8941 gatgaaacaa aagatgtaag ttttaagttg caagagatta tggatgctgt accagaagat
     9001 tctattatat attttccaaa aggaaaatac ttatttgaaa gtggtgttaa gattaagaaa
     9061 cgattaactt tatgtggaga ttcttatatt ttggcgaatg ttcctaaaaa tactgctgga
     9121 gtaacacaat ttacttttaa aggaaagaaa aatcctaaaa gtgaaaatat agcaattata
     9181 acagcaaaaa gtgtaagaca ctgtattaag agcatttgct tttattcaga tagttgtgat
     9241 agagatatga catctaatca tgaacctcca acagatggaa aacctagatt tcatcataat
     9301 gtaattataa attatagaaa tatatcggct attgtatgtg aagataaaca gggagaatca
     9361 ggtcattata aaaatctatc ttttagtggt ttttctggaa ttgcacttga tatgcctaat
     9421 aattctacag caaatgatat tacaattttt acatccggac ttggaattag tacaggagaa
     9481 aattcaacta ttgctaacag taaggtttgg ggctgtgttg atggaatgat aatttctact
     9541 ggaactttta taaatggtat gagggtagaa gaaataaaaa aagttggaat taaaaatatt
     9601 ggtagaggtt taaattttat tacaaatatc acaattgacc aatgtggata ttgtggagtt
     9661 tggtttgatt ctatatccaa tgttcagata tcaggaaata tcacaaggtg tgggcagtac
     9721 tattatgatg taagctatga taattattta atgttggata atagagttaa agaagcatat
     9781 tctttattct atggtaattt attggaatca agtaatatag ttttatcaaa taccaataaa
     9841 gataattggg aagatttcaa agaagataag cataaggtgt atcttgtaga agcacttgaa
     9901 accaagaatg tactattaac atgcaatata gatgctactg actggattgt taagtcagaa
     9961 aaaggaaatt taacgtacaa taatatgcga caaactgtta tattttacga tggaaaacta
    10021 agtagtatca atggaattgg tatatctgat gaagattatg gggataaagt caagataaaa
    10081 aaaggaaata tatatataaa tagtaaggat aaggatatta agatgcataa accagaggta
    10141 ggtgacatta tgtcaacaat tattaaagat aaaagtattc tttctgctca ttatggggga
    10201 acatgggaga aaattggtga aaaaatagag tttggaataa ctgtacacta ttataaattg
    10261 atagagaaat aagtaaatac gtagtatttg aatagatgta ttttattgga gagctaggac
    10321 tatagtttta atgtaaatgg tttggtaata gcatggattg aataatataa aaataatata
    10381 aaaaattaat ttgattatgt aaaattctat gaagtagtaa aactgtgact ttagtcatag
    10441 gaggttcaaa ctaagtaaaa gggaaaggaa tatataatat tatggaagga agaactggga
    10501 ttaaagatgg aagatggatt aatgtagtag aaagaggtat taaaaatgat ggttcgtaca
    10561 acgtaggtcc tgctttgcag gatattattg atgaaataga aacagatttt tgtgtcttat
    10621 attttccaaa aggtaaatac ctatttacaa gtggtgttaa aattaataaa gaaattgtat
    10681 tgcaaggtga ttctaattca tctacaggca ctacacaatt tataactcgt ggagtagaaa
    10741 atatgagtat tattacattg acagggaaaa aacaatgtat taaaaatata aatttttatt
    10801 ctgatagttg tgagatacag gtaaataaag aaccaccgac aaaaggtaat cctaaatatc
    10861 attatgagat gattattaat aagaatgaaa agaatgttga gatgaataat gtatcagcaa
    10921 tcctgtatga taacagtaag aatatgatta aaggtctagg tcattatgaa aatatttata
    10981 taagtggttt ttcgggtaca ggaattagga taccatatta ctcaattgta aatgatatta
    11041 cagtttcatc ttgtgggctg ggtattgata caggaataga cacaattatt tctaatagta
    11101 gaatatctaa gtgtcaaaat ggaatgagga ttagaactgg aactagtata aataatgtaa
    11161 ggattgaaaa aatacagaaa gttggtctta taagtagtca agttaagggg tatgaggggt
    11221 atggaagtta taaaattaat aatattacga ttgaccaatg tgggtattgt ggcttttcat
    11281 ttgattcaat gaaagatagt tatttttctg gtattataag aaggtgtggt cagtattatt
    11341 ataatacaga ttatgacaca tatttaagta ttaaagatag agtagaagaa gcatattctt
    11401 tattttatgg aaattatttt acagaatgta atattgattt agttagtgat aataaggata
    11461 actgggatga tggcttagaa tataaacata aagtttatgt atttaaaacc cttcaaatac
    11521 caaaattaac attgagatgc aatatagatg cctatgatta tatcgttaaa tcggtacatg
    11581 gaggaggtaa tttaatgtta aaaaataatt ttaacaatta tatatttatt gattcatcta
    11641 atccagaagt tattaatgga attaatttta attatcaaaa gaatggaaac ttgttaaggt
    11701 taaataatgg taaattaagt tataaaaatg gaaaggaaga aacagctata ttcagaccta
    11761 attatggtct tattgtagca tcaacagatt cagaatgtga acaaatagag actagctatg
    11821 gaggaaaatg ggagaagctt ggttctgaag taattggaga agaaacggta tattattata
    11881 aacatcatga accagataaa acaaaccaaa tacaataaaa tttgtattat ataatgatat
    11941 aaagttttaa tatatagtgt ttacctttaa tgtaatattg gtatatttgt atagtattaa
    12001 atttgttaaa aagtaaaatt gtagggtgct tgaaaatagc acctttttta gtttcattat
    12061 aaaattagtt ttgaaagttt aggaataatg tatatttatt tttaaagaat tataacctta
    12121 ttaaggatat tttaaatgct agaaatgaat cagtaaatca tactggaatt atcttaaatg
    12181 ttttgattaa attaagtatt tagagctata attatattaa aaatatatta gaacataatt
    12241 atattactat ggaggttaaa tatgatagta agtgtgagta gaagaactga tatacctgct
    12301 ttctatagta agtggttttt taacagactt aaagaaggtt ttgtttatgt aattaatcca
    12361 atgaatccaa aacaggttag taagatagag ttaaatccac atactgttga ttgttttgta
    12421 ttttggacaa aggatgtaac tccaatgtta tatgatttaa ataaattaaa agactataaa
    12481 tattattttc actatactat aacatcatat ggaaaagaag tagagacatg tattttagat
    12541 aaaagaaagg taatagattc atttaaggaa ttgtctagaa aaataggcaa agaaagagta
    12601 attttaagat acgacccgat tttcttaagt gaaaagtaca cagtagatta tcatatcaaa
    12661 gcatttgcga gtttatgtaa tcagcttgat ggatttacag aaaaatgtat aataagtttt
    12721 atcgatttat ataagaaaac aaaatttaat actaaagcat tacatataaa gccaatagaa
    12781 attacagaaa tagaaacatt atcaaaagag atttctaaga ttgctcataa gcatgggata
    12841 acacttgaaa tgtgttctga agaatataat ttaagtaaat ttgggattgg aaaaagtaag
    12901 tgtattgatg atagattaat atcaaaaatt ataggatgtg aagtagaggt aaaaaaagat
    12961 agtacacaaa gagatatttg tggatgtgtt aaaagtgtcg atataggaca atacaatact
    13021 tgcagacatt attgtctgta ttgttatgct aactttaatt atgcaaaagt agaagaaaac
    13081 tgtaggcttt ataaagaaga taataaatta ctcatagata ctttaagaga tgatgcaaaa
    13141 ataagcatta gagatatgaa gactattaaa gtagataaga ataaacaaat tagtatattt
    13201 gattaaaata aatatactaa ttaccttaat atattaagaa tatagatact tttgataaca
    13261 aaattaaact taatagatat tttctatata agaaagatgg tcataatatg tcaatttgac
    13321 catctttttg atataattaa aacacaaata atttagtaac aaaggaggca gaacttgaat
    13381 ttattaaaaa aatatcctat acctattgca agtttgattt tgtcaatctt tactttaggt
    13441 aacttattac aatcttatag tgaatcatta cgtaatgtaa ttggatttat aggatttatt
    13501 ttgtatgcaa tttatatagt caaaataata ttacttagaa agggtgttaa agagcaatta
    13561 gagaacactt taatatcaag tacatttcca actataacaa tggcaacaat gatatttgct
    13621 acatatataa aaccattatc tttagaatta agtattatga tttggagcat aggaattgtg
    13681 ggtcatcttg tgttaatagt cttatttagt aagaagttct tagttaaatt ctcaataaaa
    13741 acggtatttc catcttggta tatagtatat gttgggatag ttgcagctag tgttacggca
    13801 ccagcattta atcaactttt gattggcaaa attgcttttt ggataggatt tgtatcttat
    13861 atagttctta taccagtaat tttaaagaga gtatggataa tcaaggaaat gcctgaacca
    13921 tctttaccaa gtatagctat attagctgca ccagggtcac tattattgtc tggatatatt
    13981 aattcttttt cagataaaaa taatgtagta ttatacttgt tattcatatt atcaattgta
    14041 ttttatatta tagttttggg atatttaccg aaattattaa gattgccttt ttatccgagt
    14101 tttgctgcat ttacatttcc tatggcaata agtgcaatgg gtatgaaact aatgaatggt
    14161 tatttaacta aatcaggtca ttttataagt tggatttcat atgcttctaa gttagaagag
    14221 ataattgcta cagtgattat tttatatgtt ttagttttgt ttattatata tcttagtaaa
    14281 tctgaaacta catctaaagc taaataagaa ttattaaata tgtgtattta ataggaatat
    14341 tgatataaat atatgaagat aagataaacc atagaaactt aatttagctt aattttattg
    14401 gaggaaaaca aatgaaaaca aaagaagaat atttaaaaga agttagaaac atatcagaag
    14461 aatactttag aaaaggagag tttttttgct ctgaagcagt tctccagaca ataaatgatg
    14521 ctttaggcca acctttaagt ccagagataa ctaagttagc atcaggattt ccgataggac
    14581 ttggaaaggc acaatgtctt tgtggagcaa tatctggggg agagatggct ttaggtatag
    14641 tatatggaag agttcatggt gaagctatga atccaaagat gtttgagcat gctaaaggtt
    14701 tgcatgatta tattaaaaaa gagtatggtg caacatgttg tagagctatt acaaagaaat
    14761 gggatggtga taactttatg tctcccgaaa gaaaagagca ctgtattaaa ataacaggtc
    14821 aagttacaga gtgggttgca gataagctta tagaagatga aaaacttaat atcaaatagt
    14881 gtaatattag ttggtgaatt tataaagtta aatttactta tagtataaga tacttgatat
    14941 tctcgtattg atagaaaaat ttatagcata tgtatttaat gaaatatact tatatttaga
    15001 gtgtggttta atttcataaa tacatatgct attattttaa gtatataagc aaatttattt
    15061 aaataaatag aaacagttaa tttatatgta caaaactata tatgattagt gtaaataaat
    15121 acctatttta taatactcaa cataaagaca ccagacatga ttagtattat accaataaaa
    15181 atagcaagcc attctttttt gttcttcttt tctttaaaaa atataatccc tcctaaagtg
    15241 gctactatca cacaactctg agagatagaa aaacttattg taactcccaa tgtattagtc
    15301 gttatgaaca tacctaaatt tgctattgac cacaatatac cagtaattaa attgaataaa
    15361 acattttccc tatatacaat ctctttagaa aaatacttga caataataga tgaagttatc
    15421 aacataccaa cagattgagg taatataatt ctatatcctt caattaaaaa tatttgatta
    15481 gttacaacat ataatgataa aaatagagat gataataata caactccaac acattttaac
    15541 atatttttat ctgtagattt tttagtttga taatttgtga gaagtatacc aagtattata
    15601 cataatattg ataaagaacc aatcagtaac attttagaac tggtccattc attaaacaag
    15661 attacagcta ataatgtcgt aaaagttaat tgtgaaccat ttgaaattgg cattacttta
    15721 gatacactag caatttgaat tgctttaaac tgcattaatt gtcccaaact ccagaatatg
    15781 ccagaaatca tacttataca aaatgaaaaa aatgtaattt caggatgtat aaccagagtt
    15841 attatagtgg aaaatataaa cgcacttatg gatgtaccta aaagctgttc atgaggagaa
    15901 cttttcttta gatttgcaac tatgggcatc aatccccatc ccattacagg aagtaaagca
    15961 ataattattg tcagcattaa actatttcct ttcatattaa atttagacag cttttaattt
    16021 atcatctaaa attaaagtgt tcaatacata aaaattaccg tatttaatca ggaaatatta
    16081 gtagtttttt agaaaaacat tttccattaa aataaagaca aagggaagga gtaaaattga
    16141 aaatgttaac tgatatgatt caaaatcgtg aaattaaaat aataaagttt ttattaaaag
    16201 aaggtcatac aactgtaaaa gcaatagcag atgatttaga tgtttcagaa aaaacagttt
    16261 caaaatctct taaagaagta gaagcagtgc ttaaaaagat aggtctttct ttaataagaa
    16321 aacctaagat aggtgtttat attgatggag atttaaaaaa aatacttcct tacctagata
    16381 ataaaggaag tcaaattcct acaaccagag aggagagagt tatctatata tattcagtac
    16441 ttttaaagag taatgattat attactatac aacaactttc tgatgaacta tatataagtc
    16501 gtggaactat tgaaagggat ttagcagaag ttgaaaaact gctaaaaaac gaagggattt
    16561 ccatatataa gaaacctagt aagggaataa agttaaatat aagtgaaaga gataaaagac
    16621 aacttactgc taagtttata cataaatttt ggagtagaaa ctggtatatt aagcaagagc
    16681 aagaaagctt ttatcaagca tttgaaaaga tacaagcaga tgtaaatggt attttttcgg
    16741 aagatgattt atcaataatt attgatattc ttaggaattt cagcagagaa agaaaatttg
    16801 agttctctga ttatgaattt cagtcattag ttattcattt ggcaatagct gtagagagaa
    16861 ttagaaaagg cgaatatata gaagaaagtt tgtatactgg taatatagaa aataatcaaa
    16921 tgtcaaatac caattattta gcaaaacaat tagaagaaaa attttcaata ttattaccaa
    16981 aatctgaaat tggatatata aatttacatt tagtagcgtc tgaccaacat agagatacta
    17041 atgaactaaa aaatacttca actaatcctt gtgagacaag tacaaataat atatcaaatc
    17101 ttcgggaaat tataaaaaat acattgtatg agacagctta tgacaaggat ttaattgatg
    17161 gattgacttc acatgtacat tcatcaataa atagactgaa atatggactt agtattaaaa
    17221 atccatatgt aaatacaatc aaacaaaact tttctttatc atttgagcaa gctttagatt
    17281 taaagaaagt aattgaattt atatatgata ttaggataaa tgatgatgaa tgtgcttata
    17341 tagcattaca ttttgaagct tttagagaaa gaatgaaaga acttccacaa aatattagag
    17401 taattctagt atgcagtaca ggattaggtt catctaggtt attgtctgca agaataaaaa
    17461 aatactttcc aatgataaag attgaaaaag tactttccgt acaagaatta gtatccagta
    17521 aaattgatgc agatttagta ataagtacta tttatttaga gttagaaaca attccaacca
    17581 tagtagttag tcctatttta aatgaaagtg atataagaac cttggaaaga aatatacaaa
    17641 atgtttcaag ttgtacttct aagaagtata aatctttcag aaacttaatc tttgaagaaa
    17701 atatattgtt gaatattgaa gcttcaaact atgaagatgc aattaagtat ataacagata
    17761 acctaataaa aaaaggtttt gcaaaagaag gtatagctaa aagtgcaatt gagagagaaa
    17821 atttatctta cacttctttc caatcaatag ctacacctca tgctaatcct agttatatta
    17881 aaaaatctaa tatatctgtt gcaacgttaa aaaatcctat tacatgggga aatgaaaagg
    17941 tggaagttat tttctttatt tcattagaaa atgacaaaaa cctagagctt gatgaaatat
    18001 atgaagtttt ttatgacttt attgacaata aaaaaaatat aaatgacata ttaagtgcaa
    18061 cttccacaaa ggaagtgtac gatttgctag tggaggagag tatatagtga aaatatcaga
    18121 tgtattgaaa aaagagcaaa ttgtttttaa tcttgataca aatacaaagg aagaaacaat
    18181 aaaaaaatta agtagtatat ttgttgaaaa tgggattgtg gacaatgaag aagaatatgt
    18241 taagtctgtt ttggaaagag aagaacattc aactacaggt attggtaatg gtattgctat
    18301 tcctcatggg aaaagtaatg ctgtcaaaaa atcttctata atatttgcaa agactaagca
    18361 taagattgaa tgggatgctt tagatgaaaa accagtagat agtattttct tattggctat
    18421 aagcaatatt gataaggata gcaatcatct tgtactatta tctaaattag caactaaact
    18481 tatggatgat gacaatgtag atgcactaaa attagccaat tcagaacaag aaataatcaa
    18541 tatatttagt gaagaaggag agatgtagaa atgaaaagaa aaattatagc agttacagca
    18601 tgtgcaacag gagttgcaca tacatatatg gcagctcaag cattaaagaa agcttcaaaa
    18661 aagatgggtc accttataaa agttgaaaca caaggagcta caggaatcga taatgagtta
    18721 actacaaagg atgcacaaat tgcagaagta gtaatatttg cagtagatac taaagtcaga
    18781 aatgctgaac gttttgaggg aaaagaaata ctagaagtac cagttaatgc acctataaag
    18841 gatgcagaga aagtaataaa tgatgcatta aagttaattg acactaaata aatggaggga
    18901 aatgtaatgt tgaaaaagat agtctctgag ttaaaaaagc atgtcttaac tggaatctca
    18961 tatatgattc cattagtaat tgcaggtgct atgataatgg cgatatctcg tgtaggtggt
    19021 tctttctata atataccaga tatatgggat gctaaatatg cagaaagtgc tagtagtatt
    19081 gttagattat tacatgattt agatgggttt ggaggtactg cattaggatt aatgtttcct
    19141 gtaattgctg catttatagg attttctata gctgataaat tagctattgt accaggtctt
    19201 gttggaggta tgattgctaa agatataggt gcaggatttt taggagcttt ggcagttggt
    19261 cttatagcag gatatacatg tttgtttatt aaaaatcatg ttaaattacc aaaatcagca
    19321 gcttcaatag taccaatatt tatagtacca gtatttggga cattaatcac tgttgtatta
    19381 atcaattatg tgataggtat accttttgcc acattaaata ctggattaga aaattggtta
    19441 aatggattat ctggtacaaa tcagatacta atggcagcta ttataggggc tatgatggca
    19501 gttgacttag gtggaccagt taataaagca gctttaacaa catcacttgc attattaaca
    19561 agtggaattt atgcgcctaa cactgctgca atggtaggaa tagttatacc accactagga
    19621 ttgggacttg ctactatact agcaaaacaa aaatataata aacagttacg tgaagctgga
    19681 aaatcatctc ttataatggg tttaattgga gtaagtgaag gagcaattcc ttttgcggta
    19741 gaatctccat taaaagtaat accttcatgt gtaattggaa cagcaattgc ttcagctatg
    19801 gcagttggtt taggttcagt aaatgcaact ccaattagtg gattttatgg atggtttaca
    19861 gtagagaatt ggccaatgta tgtgttatca atagcagttg gaacagtaat tgtagctgga
    19921 ttagttatag tattgcgtgg aaatccagtg attgaggatg atgaatttga agatgatgat
    19981 tttgatgaag cagagtggga atcttaaaat ttaataacta tttaagacgt gttataagct
    20041 atattcaata tgaatcttat actaaataaa gtgttaaata ttcagtttag acttaaatat
    20101 aaaagataaa gaacagagga gaataaatga taaaagcaca tattgttaat catacacact
    20161 gggatagaga atggtatttt acttctggag atgcattagt acttagtgaa caactattta
    20221 cagatgtaat tgatgaatta gaacgtaatc cagatgtaag ttttgtactt gatggacaac
    20281 tttctatttt ggatgattat gtacaattac acaaagaaaa aatagaaatc attaaaaagt
    20341 taataaaaga agatagacta catattggac catggtttac tcaaactgat gcattctttg
    20401 ctagaggaga gtctatttta agaaacttaa tgattggaat ttttgaaagt aaaaagtatg
    20461 gtaagtatat gaaaattggg tatttgccag atacatttgg atttaatgca cagatgccta
    20521 tactattaaa gcatgtaggt cttgataata tattcttttg gagaggtata catcttggta
    20581 aacaggttca atcaccatat tttaagtgga aaagcttaaa tggagaaagt tatatatatg
    20641 cagtaaatat gccacatgga tatggaactg gtatgctttt agagccttca ttaaagtatg
    20701 ttaatggacg cttagaccca gctattgatt ttattaaatc atatactgat gtagatgagg
    20761 tgttaatacc ttctgggaat gaccagttaa atataatagg tgatttcaaa aataaaatta
    20821 aagcgattaa tgatatcgga aagtattcat atataacgag ttcatatcaa gagtttttaa
    20881 aatatataaa gtccatagaa tcactagaaa gctatagagg tgaatttaga gaacctgtat
    20941 tagcaagaat acataaatca attggttcta gtagaatgga tataaaatta gcatgtgata
    21001 aactagaaaa caagctgatt aaaagaatag agccattatt agtaattgct aaaaagagca
    21061 aaattgaaat aagcaatcag ttacttataa atacatggaa aaaacttttg gaaggacaag
    21121 cacacgatag tttagctgga tgtgtaactg atactgtaac agatgatatt cttcaccgta
    21181 taagagaagc aaatgaaata tgtgacagta ttgaaaatac tattgtaaaa aagatttcag
    21241 aagggcttaa attatctaaa aatgatattt tagtatttaa tacagaagct aagcgtttta
    21301 atggatataa agagatacaa gttgtaagtg atagtaaaaa tatttatttt aaagataatt
    21361 tagatgctac tataattgaa gaaacttatg taaaaccgag agaaaatgta ttagaagaaa
    21421 cacctgctgg taatatattt attgaagaac caggatatta tatattaaaa gtaagaataa
    21481 atgtacagct tcctgcactt ggttataaag ttgttagttt tgaattaagt gataaagaaa
    21541 tggtgtcact tgataaatct aatgacactt ttatatctaa tgataattat aagataatat
    21601 atgaagatgg aagcttaaat ttacaactta aagatggaac ttacatatca aactttttaa
    21661 cattaaaaga tagtggtaat gcaggtgata cctatgactt ttctccacta aaaaatgatg
    21721 agaatataaa actttcgttt gataaagtgt atacagaaaa agctttagga tatgaaaaaa
    21781 tggtggttaa aggtactact ttactaccac ttacattaga agatagaaaa aacaaatatc
    21841 ttaatggtaa attaaatgta aaagtaagta ttgtcttatc taaagaaaac ccattgatgg
    21901 atgtaaaact ttgtgttgat aacacgatat ataatcatag actacgtgtt catataaaaa
    21961 ctgatataaa agataataaa aacatagcat cattgccatt tggatatata acaagaaaaa
    22021 atggagtttt agacaactgg gaagatattt acagtgaaat gcctatagat ttagaacctt
    22081 tggaaagtaa tattacgctt acaaaccaaa atagaagttg tactgtattt actagaggaa
    22141 taaaagagta tcaacatatt gaagatgaaa ttgcattgac cttacttgct actacagatg
    22201 aactaggaaa gcctgattta ttatatagac caggacgtgc ttctggtgat acaactaaaa
    22261 aaggtcatat aagaattaaa acagataaag ctcaaatgct taaggaatta gaattttcat
    22321 ttgcaatata tatggattct aaatcatttg atgaattgga aattgcgaat ttaacccaca
    22381 attatctaag ggaatgtgta aattatcaat tacaggatta caatttcttt ttatatcata
    22441 tagataataa gattcaaaaa tcaattgtca ataaaactgt aagtagagaa ttagaaataa
    22501 tatctttacc agaaaactat cttatatcag catgttatcc ttcttattac agtaaagata
    22561 aatttataat aagagtggaa aatccaagta gtaatagaat gatattggat gagcaaatat
    22621 ttaaaaatag aaatgggaaa attgtaaatg caatagaaga tgtagaagag gaacaggtat
    22681 atgaaatagc accttttgac gttatttcaa tattattgga tttataagtg taaaagtaag
    22741 tttattgttt aaagtctgac agatattaat ctgccagact ttttaatttg tataaatttg
    22801 ggtaaatatt aatgaatggt tttagtattt aagtatgaat ttagtattta atatagaatt
    22861 tattgaagta gaataattag tttaacagga taagcagttt aaataaagaa ttattatatt
    22921 agagtgattt tatatataat ttaaaataat aaaattttaa taaaatgagt taaagattgt
    22981 atattaatag agttgatgta gttacaaaaa agttaccaat tgttatgtat ttacaaaact
    23041 gatat
//
LOCUS       DAEPHU010000067        22313 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 01A10CD0081
            SAMN05941466-rid12468953.denovo.067, whole genome shotgun sequence.
ACCESSION   DAEPHU010000067 DAEPHU010000000
VERSION     DAEPHU010000067.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941466
            Sequence Read Archive: SRR6291087
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 22313)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22313)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068158.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 22:43:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,892
            CDSs (total)                      :: 3,805
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 87
            rRNAs                             :: 8, 1, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 55
            CDSs (without protein)            :: 55
            Pseudo Genes (ambiguous residues) :: 0 of 55
            Pseudo Genes (frameshifted)       :: 21 of 55
            Pseudo Genes (incomplete)         :: 28 of 55
            Pseudo Genes (internal stop)      :: 16 of 55
            Pseudo Genes (multiple problems)  :: 8 of 55
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22313
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941466-rid12468953.denovo.067"
                     /strain="01A10CD0081"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            <1..369
                     /gene="tuf"
                     /locus_tag="KR231_002779"
     CDS             <1..369
                     /gene="tuf"
                     /locus_tag="KR231_002779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009887863.1"
                     /note="EF-Tu; promotes GTP-dependent binding of
                     aminoacyl-tRNA to the A-site of ribosomes during protein
                     biosynthesis; when the tRNA anticodon matches the mRNA
                     codon, GTP hydrolysis results; the inactive EF-Tu-GDP
                     leaves the ribosome and release of GDP is promoted by
                     elongation factor Ts; many prokaryotes have two copies of
                     the gene encoding EF-Tu; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HBH0005141.1"
                     /translation="DNIGALLRGVQRNEIERGQVLAKTGSVKAHTKFTAEVYVLKKEE
                     GGRHTPFFDGYRPQFYFRTTDVTGACKLPEGIEMVMPGDNVTMEVDLINSIVVEEGLR
                     FSIREGGRTVASGVVATIIE"
     gene            741..1052
                     /gene="rpsJ"
                     /locus_tag="KR231_002780"
     CDS             741..1052
                     /gene="rpsJ"
                     /locus_tag="KR231_002780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S10"
                     /protein_id="HBH0005142.1"
                     /translation="MAKNEKIRIRLKSYDHKLLDFSAGKIVETAKKAGSQVSGPVPLP
                     TEKQVVTILRAVHKYKDSREQFEIRTHKRLIDIANPTPKTVDSLMRLDLPAGVDIEIK
                     L"
     gene            1144..1773
                     /gene="rplC"
                     /locus_tag="KR231_002781"
     CDS             1144..1773
                     /gene="rplC"
                     /locus_tag="KR231_002781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421173.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L3"
                     /protein_id="HBH0005143.1"
                     /translation="MKGILGKKVGMTQIFTDKGVVIPVTAVEAGPMVVTQIKTVDKDG
                     YNAIQIGFEDAKEKALNKPKKGHLAAANVLKKHLKEFRVDSVEGYTVGQEIKADVFEA
                     GAKIDVTGISKGKGFQGPIKRHGQSRGPETHGSRYHRRPGSMGACSYPGRVFKNKKLA
                     GHMGSVKVTVQNLEVVKVDADKNLILVKGAIPGAKGSVVTIKEAIKVSK"
     gene            1803..2426
                     /gene="rplD"
                     /locus_tag="KR231_002782"
     CDS             1803..2426
                     /gene="rplD"
                     /locus_tag="KR231_002782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001127258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L4"
                     /protein_id="HBH0005144.1"
                     /translation="MPKLNVLNVSGQNVGEIELSDSIFGVEVNGHVLYEVVKNQLANK
                     RQGTQSAKTRAEVRGGGRKPWKQKGTGRARQGSTRSVQWVGGGVAFAPKPRSYKYTLP
                     KKVRRLAMKSALSSKVQNSEVIVLDALNMDAPKTKEFAQILNNINAAKKALVVIADKN
                     DNVIKSARNIEGVQTALVNTMNVYDILKYDSFIITTDAVKKVEEVYA"
     gene            2426..2716
                     /gene="rplW"
                     /locus_tag="KR231_002783"
     CDS             2426..2716
                     /gene="rplW"
                     /locus_tag="KR231_002783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001205558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L23"
                     /protein_id="HBH0005145.1"
                     /translation="MTNPHDVIIRPVVTEHSMAEMGEKKYTFVVAKDANKTEIKKAVE
                     KVFGVSVDKVNTLNYDGKVKRMGRTQGRTSSFKKAVVKLTADSKEIEFFQGM"
     gene            2746..3576
                     /gene="rplB"
                     /locus_tag="KR231_002784"
     CDS             2746..3576
                     /gene="rplB"
                     /locus_tag="KR231_002784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L2"
                     /protein_id="HBH0005146.1"
                     /translation="MAIKKFRPTSPALRQMTVLVSDEITCNQPEKSLLVNLKKNAGRN
                     VHGRITVRHRGGGQKRKYRIIDFKRDKDGIPAKVATIEYDPNRTANIALLNYADGEKR
                     YILAPVGINVGDTILSGLGADIKPGNCLALKDMPVGTIIHNIELKPGKGAQLVRSAGV
                     SAQLMAKEGKNALLRLPSGEMRLVSINCKATIGQVGNIEHGNVVIGKAGRKRHMGIRP
                     TVRGSVMNPNDHPHGGGEGRSPIGRPSPVTPWGKPALGYKTRKKNKASNKLIVSRRTK
                     "
     gene            3611..3892
                     /gene="rpsS"
                     /locus_tag="KR231_002785"
     CDS             3611..3892
                     /gene="rpsS"
                     /locus_tag="KR231_002785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003454422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S19"
                     /protein_id="HBH0005147.1"
                     /translation="MSRSTKKGPFVHARLLKKIEAMNASGNKEVIKTWSRSSTVFPQM
                     VENTIAVHDGRKHVPVYITEDMVGHKLGEFVPTRTFKGHKDDEKSNKRK"
     gene            3924..4259
                     /gene="rplV"
                     /locus_tag="KR231_002786"
     CDS             3924..4259
                     /gene="rplV"
                     /locus_tag="KR231_002786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018590372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L22"
                     /protein_id="HBH0005148.1"
                     /translation="MEAKATAKYVRVSPRKAGQICDLVRGKNVDEALAILKFTPRGAA
                     SIIAKVVKSAKANAENNHEMDTEKLYIASIVANQGPTMKRFMPRAMGRATTIRKRTSH
                     IEVVVKEKK"
     gene            4282..5097
                     /gene="rpsC"
                     /locus_tag="KR231_002787"
     CDS             4282..5097
                     /gene="rpsC"
                     /locus_tag="KR231_002787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S3"
                     /protein_id="HBH0005149.1"
                     /translation="MGQKVNPHGLRVGVIKDWDSRWFATDKKEFGNLLLEDHNIRKFL
                     KKRLYSAGVAKIEIERSANKIKMDLHVAKPGVVIGRAGAGIEALKAELEKMTKKTIIV
                     NIVEVRSTDKNAQLVAENIALAIERRVAFRRAMKQAIQRAMKSGAKGIKVSASGRLGG
                     AEMARTEGYSEGNVPLQTLRADIDYGFAEADTTYGKIGIKVWICNGEVLPTRDGVNPR
                     EESRKSDRRDNKRDNRRNDRRGNDRRGNDNRGNYRGQRPQGGSRPQRTENKGN"
     gene            5133..5564
                     /gene="rplP"
                     /locus_tag="KR231_002788"
     CDS             5133..5564
                     /gene="rplP"
                     /locus_tag="KR231_002788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L16"
                     /protein_id="HBH0005150.1"
                     /translation="MLMPKRVKRRRVHRGSMAGQAHKGNKVTYGEFGLVALEASWITS
                     NQIEAARIAMTRYIKRGGKVWIKIFPHKPVTRKPAETRMGAGKGSPEYWVAVVKPGRV
                     MFELAGVSEDKAREAMRLAAHKLPIKCKFVKKEDLEVKGGE"
     gene            5566..5769
                     /gene="rpmC"
                     /locus_tag="KR231_002789"
     CDS             5566..5769
                     /gene="rpmC"
                     /locus_tag="KR231_002789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005810148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L29"
                     /protein_id="HBH0005151.1"
                     /translation="MKAKELRDLTSEELMNKLNDFKSELFSLRFQLATGQLENTARIK
                     FVKKDIAKVKTVLAERKLYETRA"
     gene            5793..6047
                     /gene="rpsQ"
                     /locus_tag="KR231_002790"
     CDS             5793..6047
                     /gene="rpsQ"
                     /locus_tag="KR231_002790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018590376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S17"
                     /protein_id="HBH0005152.1"
                     /translation="MERGRRKVRIGRVVSDKMDKTIVVAVEEFVRHPLYNKRVKRTKK
                     FKAHDEKNICNIGDRVKIMETRPLSKDKRFRLVEVVEKVK"
     gene            6073..6441
                     /gene="rplN"
                     /locus_tag="KR231_002791"
     CDS             6073..6441
                     /gene="rplN"
                     /locus_tag="KR231_002791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007885948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L14"
                     /protein_id="HBH0005153.1"
                     /translation="MIQQESRLRVADNSGAKELLCIRVLGGSKRRYGNIGDVIVATVK
                     SATPGGVVKKGKVVKAVIVRSKQGVRRNDGSYISFDENAAVIIKDDKTPVGTRIFGPV
                     ARELRDNEFMKIVSLAPEVL"
     gene            6465..6770
                     /gene="rplX"
                     /locus_tag="KR231_002792"
     CDS             6465..6770
                     /gene="rplX"
                     /locus_tag="KR231_002792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L24"
                     /protein_id="HBH0005154.1"
                     /translation="MRVKKGDTVVVIAGKDKGKKGSVLKVYPKTSKVLVEGVNVITKH
                     QKPSAMNQQGGIINKEAPIHISNVMPFDPETGKGVRVRYEVKDGNKVRVSAKSGKEL"
     gene            6800..7342
                     /gene="rplE"
                     /locus_tag="KR231_002793"
     CDS             6800..7342
                     /gene="rplE"
                     /locus_tag="KR231_002793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018590379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L5"
                     /protein_id="HBH0005155.1"
                     /translation="MASRLQEKYMKEVAPALMEKFGYKNVMEIPKLNKIVINMGIGDA
                     RENPKGLEKGVEELEMISGQKPVITKARKSVANFKLREGMPIGTKVTLRADKMFYFMD
                     KLVSVSLPRVRDFRGVNPNAFDGRGNYALGVKEQLIFPEIEYDKIDKVRGMDIIFVTT
                     AKTDEEARELLKLLGMPFSK"
     gene            7360..7545
                     /locus_tag="KR231_002794"
     CDS             7360..7545
                     /locus_tag="KR231_002794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type Z 30S ribosomal protein S14"
                     /protein_id="HBH0005156.1"
                     /translation="MARKAMVVKQQRKQKYATREYTRCTICGRPHSVLKKFGICRICF
                     RELAYKGQIPGVRKASW"
     gene            7578..7976
                     /gene="rpsH"
                     /locus_tag="KR231_002795"
     CDS             7578..7976
                     /gene="rpsH"
                     /locus_tag="KR231_002795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012158382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S8"
                     /protein_id="HBH0005157.1"
                     /translation="MTMTDPIADMLTRIRNANVVKHETVDVPASNMKKELARILLEEG
                     FIRGYDVIEDGKQGIIRIQLKYGQEGERVITGLKKISKPGMRVYAANHEIPKVLNGLG
                     ISVISTSKGILTDKQARKENVGGEVICYVW"
     gene            8007..8549
                     /gene="rplF"
                     /locus_tag="KR231_002796"
     CDS             8007..8549
                     /gene="rplF"
                     /locus_tag="KR231_002796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L6"
                     /protein_id="HBH0005158.1"
                     /translation="MSRIGVKPIIIPAGVEVTIAEGNLVTVKGPKGTLTKQLSAELNI
                     KKEENTIMVERPTDNKKHRSLHGLTRTLLDNMVVGVNTGFEKKLELKGVGYRAQKQGK
                     KLVMNLGFSHPVEMEDPEGITVEAPNQTELIVKGIDKQLVGNYAAKIRAWRKPEPYKG
                     KGIKYVDEVIRRKEGKTGKK"
     gene            8585..8953
                     /gene="rplR"
                     /locus_tag="KR231_002797"
     CDS             8585..8953
                     /gene="rplR"
                     /locus_tag="KR231_002797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000628816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L18"
                     /protein_id="HBH0005159.1"
                     /translation="MLKKADKNANRLQRHKRVRRKISGTSQRPRLCVFRSANNIYAQI
                     IDDTKRVTLVAASSLEAEVKSAVNHTGNKEAAKKVGELVAKKAVEKGITEVVFDRGGY
                     LYHGRIQELAEGAREAGLKF"
     gene            8974..9483
                     /gene="rpsE"
                     /locus_tag="KR231_002798"
     CDS             8974..9483
                     /gene="rpsE"
                     /locus_tag="KR231_002798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011109776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S5"
                     /protein_id="HBH0005160.1"
                     /translation="MLRRKPIDAGQLDLQEKVVEVRRVTKVVKGGRNFRFAALVVVGD
                     ENGHVGIGAGKAMEVPDAIKKAVEDAKKNLIVVPIVGTTIPHEVRGHFGAGNILIMPA
                     VEGTGVIAGGPARAVLELAGLKDVRAKSLGSNNPRNMVNATIEGLNSLKTVEDIAKLR
                     GKKVEELLG"
     gene            9498..9683
                     /gene="rpmD"
                     /locus_tag="KR231_002799"
     CDS             9498..9683
                     /gene="rpmD"
                     /locus_tag="KR231_002799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421137.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L30"
                     /protein_id="HBH0005161.1"
                     /translation="MAKLQIKLVRSVIGTTPNQKKNVEALGLRKREQVVVKEDNAQTR
                     GMINKVSHLLEVTEIAE"
     gene            9716..10159
                     /gene="rplO"
                     /locus_tag="KR231_002800"
     CDS             9716..10159
                     /gene="rplO"
                     /locus_tag="KR231_002800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000766080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L15"
                     /protein_id="HBH0005162.1"
                     /translation="MKLHELKPAEGAVRAKRRLGRGTATGQGKTAGRGQKGQWSRSGG
                     GVRVGFEGGQMPLARRLPKRGFNNIFKKVYTEVNVEVLNRFENGTEITAELLKSTKTI
                     SKIGKDGIKILGEGNLEKALTVKAAKFTASAQEKIEKAGGKAELV"
     gene            10203..11471
                     /gene="secY"
                     /locus_tag="KR231_002801"
     CDS             10203..11471
                     /gene="secY"
                     /locus_tag="KR231_002801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecY"
                     /protein_id="HBH0005163.1"
                     /translation="MLSKLKQAWKIKAVRKKVMYTLMMIVIFRIGTTIPVPGIDTSII
                     QKMVGGNSLLSLYNMFTGGAFSNFSLFALGISPYITASIIIQLLTVGFESLAELQKSG
                     EEGKKKINKYTKYTALALAVVQALGITLGIVRSALISNSVFFITTVVITLVSASMLVM
                     WIGDKITEKGIGNGSSVIIFAGIISRIPTDVIKISQQVKSGEVAPWVIVILAVVILLT
                     VTGVTFIQEATRKIPVQYAKRVVGRKMYGGQSSHIPMKVNQSGVMPIIFASSLLAFPQ
                     TIAMFMGPNAQAFVQKYLSMATEQGFWTYRSIEILLIIFFSYFYTTVSFNTEDISKNM
                     KNNGGFIPGIRPGEPTMDYLNRILTRLTLAGATFLAIIAMVPALTTHYMKVNMSLAGT
                     SLLIVVGVALELKRQLESNLVMRSYQGFLK"
     gene            11488..12138
                     /locus_tag="KR231_002802"
     CDS             11488..12138
                     /locus_tag="KR231_002802"
                     /EC_number="2.7.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009904768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylate kinase"
                     /protein_id="HBH0005164.1"
                     /translation="MRIILLGPPGAGKGTQAAGIVEKYNIPHISTGDIFRKNIKEGTE
                     LGKKAKEYMDQGLLVPDELTVGLVTDRISQEDCKNGFMLDGFPRNVAQGEHLDIFLKN
                     AGISLDKVVNIEVDKSILVSRAVGRRICKSCGATYHVEFNPPKVEGVCDVCQGELYQR
                     ADDNEETVSKRIQVYLDETKPLVDYYSKQGIIADIKGDQAIDKVFEDIVAALGSGK"
     gene            12139..12885
                     /gene="map"
                     /locus_tag="KR231_002803"
     CDS             12139..12885
                     /gene="map"
                     /locus_tag="KR231_002803"
                     /EC_number="3.4.11.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I methionyl aminopeptidase"
                     /protein_id="HBH0005165.1"
                     /translation="MIILKSKKEIELLREAGKIVADTHEVLRKAISPGISTLELDKIA
                     EENIRKYNAEPSFKGYGGFPGSICASINREVVHGIPGETILQEGDIVSLDIGAYYKGY
                     HGDSAKTHGVGMISEEDRKLIEVTRESFYEGIKFAKLGYRLSDISHAVQTHVEKHGFS
                     VVRDLVGHGVGANLHEDPQVPNYGLPGKGPRLREGMVIAIEPMVNAGRYHVKTLSDGW
                     TTVTIDGKKSAHYEHTIAITEHEPLILTKL"
     gene            12907..13176
                     /locus_tag="KR231_002804"
     CDS             12907..13176
                     /locus_tag="KR231_002804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KOW domain-containing protein"
                     /protein_id="HBH0005166.1"
                     /translation="MLSDNLSIGQVVKVSLGRDKGNLFFVVKIINNEYVLIADGKKRK
                     LDKPKLKKVKHLKKYNFINDEVRKRVVSGQEITDSFLRAELTKLN"
     gene            13214..13432
                     /gene="infA"
                     /locus_tag="KR231_002805"
     CDS             13214..13432
                     /gene="infA"
                     /locus_tag="KR231_002805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001029884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-1"
                     /protein_id="HBH0005167.1"
                     /translation="MAKKDVIELEGTVSEALPNAMFKVKLENGHEILCHISGKLRMNF
                     IRILEGDKVNVELSPYDLTRGRITWRKK"
     gene            13468..13581
                     /gene="rpmJ"
                     /locus_tag="KR231_002806"
     CDS             13468..13581
                     /gene="rpmJ"
                     /locus_tag="KR231_002806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003720928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L36"
                     /protein_id="HBH0005168.1"
                     /translation="MKVRPSVKPICEKCKVIKRKGKVMVICENPKHKQKQG"
     gene            13734..14105
                     /gene="rpsM"
                     /locus_tag="KR231_002807"
     CDS             13734..14105
                     /gene="rpsM"
                     /locus_tag="KR231_002807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005810116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S13"
                     /protein_id="HBH0005169.1"
                     /translation="MARIAGVDLPREKRAEIGLTYIYGIGKATANEILAKAEINPDTR
                     IKDLSEDQVNELRKVIDDDFLVEGDLRREIALNIKRLRDIKCYRGIRHAKGLPLRGQR
                     TKTNARTRKGPRKTVSRKKKK"
     gene            14141..14539
                     /gene="rpsK"
                     /locus_tag="KR231_002808"
     CDS             14141..14539
                     /gene="rpsK"
                     /locus_tag="KR231_002808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006440523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S11"
                     /protein_id="HBH0005170.1"
                     /translation="MAKPKKKVTRIRRRERKNIERGHAHIQSTFNNTIITLTDVHGNA
                     ISWASSGQLGFKGSRKSTPFASQMAAETAAKAAMEHGLKSVEVFVKGPGSGREAAIRA
                     LQATGLEVTMIKDVTPIPHNGCRPPKRRRV"
     gene            14571..15194
                     /gene="rpsD"
                     /locus_tag="KR231_002809"
     CDS             14571..15194
                     /gene="rpsD"
                     /locus_tag="KR231_002809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S4"
                     /protein_id="HBH0005171.1"
                     /translation="MARYTGASCRQCRREGMKLFLKGDRCYTDKCAIVKRNYAPGQHG
                     QGRKKVSNYGLQLREKQKVKRIYGVLETQFRNLYERAENMPGKAGENLLSLLERRLDN
                     VVYRMGLASSRKEARQLVTHGHFTLNGNKVDIPSLIVKVGDVIEVKEKSRSSAKFKNL
                     VEVNSRIAPKWLEANVEGMTAKVVGVPTREDIDLEIAEHLIIELYSK"
     gene            15272..16219
                     /locus_tag="KR231_002810"
     CDS             15272..16219
                     /locus_tag="KR231_002810"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit alpha"
                     /protein_id="HBH0005172.1"
                     /translation="MIEIEKPKVDIVELSEDYRYGKFVIEPLERGYGITIGNALRRIL
                     LSSLPGVAVNAIKIDGVLHEFSTIPGVKEDVTEIILTLKELSATIDGEGSRTLKIEAQ
                     GPCSITGADIICPPDVEILSKDLAIATLDDNAKLNMEIFVDKGRGYVSAEENKTENVP
                     IGVLPVDSIYTPVEKVSYHVENTRVGQKTDYDKLVLEVWTNGSINPQEGISLAAKVLV
                     EHLNLFIDLTEHVSSVEIMVEKEEDQKEKVLEMTIEELDLSVRSYNCLKRAGINTVEE
                     LANKSEDDMMKVRNLGKKSLEEVIQKLEELGLGLKPSEE"
     gene            16240..16581
                     /gene="rplQ"
                     /locus_tag="KR231_002811"
     CDS             16240..16581
                     /gene="rplQ"
                     /locus_tag="KR231_002811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003357477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L17"
                     /protein_id="HBH0005173.1"
                     /translation="MAKYRKLGRETAHRNLMLRNLVTCLLRSGRIETTVTRAKETRRM
                     AEKMITLAKRGDLHARRQVLAYVMDETVVNNLFTDLAPKYAERNGGYTRIIKIGPRKG
                     DAAEMAFIELV"
     gene            16701..17534
                     /locus_tag="KR231_002812"
     CDS             16701..17534
                     /locus_tag="KR231_002812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter ATPase"
                     /protein_id="HBH0005174.1"
                     /translation="MDNIVKVNNISFEYITDEAKLKAIDNLSLDVKKGEFVAIIGHNG
                     SGKSTLSKNLNAILMPTEGNILIDDMDTKEEERLWDIRQTAGMVFQNPDNQIVATIVE
                     EDVAFGPENLGIEPKEIRRIVEESLKSVGMYDLRDRQPHLLSGGQKQRVAIAGIIAMR
                     PKCIIFDEATAMLDPSGRKEVMKTIKRLNKEENITVIHITHFMEEAVEADRVVVMEKG
                     KKILEGTPREVFSKIKMLKEIGLDVPCMTELSSLLIEEGINISSDILTVDEMVMELCQ
                     L"
     gene            17522..18388
                     /locus_tag="KR231_002813"
     CDS             17522..18388
                     /locus_tag="KR231_002813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter ATPase"
                     /protein_id="HBH0005175.1"
                     /translation="MSIIVKNLTHIYNEGMPFASKALDDVSFEIKDRDFVGLIGHTGS
                     GKSTLIQHLNGLLKPSSGEIFINDFNITDKNLNLTEIRKRVGVVFQYPEYQLFEETID
                     KDIAFGPSNLGLEESEIHNRVKASMEAVGLDYEGFKDKSPFELSGGQKRRVAIAGVIA
                     MNPEVLILDEPTAGLDPGGRDEIFNLIKDLHEKKNMTIILSSHSMDDMAKLAKTLIVM
                     NHGSVEFMGTPREVFKSNASKLKDIGLDIPQVLELALKLREKGFDISEDILTLEEAKQ
                     EILKVVRGRGLC"
     gene            18382..19185
                     /locus_tag="KR231_002814"
     CDS             18382..19185
                     /locus_tag="KR231_002814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HBH0005176.1"
                     /translation="MLKDITIGQYYPTSSAIHKLDPRIKLVATIVFMVSIFVVNKFWP
                     YIVVLLCLLAMIKLANIPVKYIVKGVKPLKWIILFTFLINIFFLPGDEIWSFGFLAIT
                     KQGLRQAIFMAIRLIFLVVGTSLLTLTTSPIELTDGIERLLNPFKKIGLPVHELAMMM
                     TIALRFIPTLLDETDKIMKAQMSRGADFESKNLINRAKNLVPLLVPLFVSAFRRADEL
                     AMAMEARCYRGGHNRTKMRESVISRRDYMACVFQVVYLGAIIATRFIAI"
     gene            19217..19948
                     /gene="truA"
                     /locus_tag="KR231_002815"
     CDS             19217..19948
                     /gene="truA"
                     /locus_tag="KR231_002815"
                     /EC_number="5.4.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003514691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(38-40) synthase TruA"
                     /protein_id="HBH0005177.1"
                     /translation="MRNIKIKIQYNGKNYCGWQKQPDSLGIQGTIERAIYDITKEETS
                     LIGSGRTDSGVHAIGQIANFKINSGISIESIPMALNAKLPKDISVIEACEVNDDFHSR
                     YSAKGKTYKYLVYNSKFRNPILSEISYQVKYELDFDKMCSEAKSLLGTHDFKGFMSSG
                     SSVKDTVRTIYDIDISKKDDLITFEISGNGFLYNMVRIIVGTLVDMGRGRINEPFLDI
                     IQSKTRSRCGHTAPAQGLFLKKVHY"
     gene            20068..20499
                     /gene="rplM"
                     /locus_tag="KR231_002816"
     CDS             20068..20499
                     /gene="rplM"
                     /locus_tag="KR231_002816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L13"
                     /protein_id="HBH0005178.1"
                     /translation="MKSYIAKPADVQRKWYLVDAEGKTLGRLATEIATVLRGKHKPTF
                     TPHVDGGDFVVVVNAEKIVLSGKKLDQKYYRYHTGYVGGLKEISYRDMMDKKPEEVIS
                     HAVSGMLPKNKLRSRMMTRLRVFAGAEHTHAAQNPEVLNFK"
     gene            20528..20920
                     /gene="rpsI"
                     /locus_tag="KR231_002817"
     CDS             20528..20920
                     /gene="rpsI"
                     /locus_tag="KR231_002817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003515879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S9"
                     /protein_id="HBH0005179.1"
                     /translation="MANVQYYGTGRRKSSVARVRLVAGEGNILVNGRALENYFNYETL
                     IRDVKQPLVLTGNENKYDVIVKVEGGGFTGQAGAIRHGISRALLKADLDLRPALKKEG
                     FLTRDARMKERKKYGLKAARRAPQFSKR"
     gene            21379..22131
                     /gene="cwlD"
                     /locus_tag="KR231_002818"
     CDS             21379..22131
                     /gene="cwlD"
                     /locus_tag="KR231_002818"
                     /EC_number="3.5.1.28"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase CwlD"
                     /protein_id="HBH0005180.1"
                     /translation="MEYYSVFISIHIQGDVVRKYIKHIIFSFAMICLVVVSIFEIKNI
                     SEDVIKYMPVTNKTIILDAGHGGIDPGALNKDKSTSEKDINLAITLKLRELIESSGGL
                     VILTREDDSSLYKEENNKTTRQKYNENLKNRKEIISNSNANMFVSIHLNAFEQSKYYG
                     AQTFYPKDKQDSKELSKCIQEELKRVVDKTNNREVKPRDDIYLLKENNIPSVLIECGF
                     LSNEKECKLLTDETYQEKIAWAIYIGIQKYLS"
BASE COUNT         8969 a         2609 c         4585 g         6150 t
ORIGIN      
        1 gataatatag gagcattatt aagaggagta caaagaaacg agatagaaag aggacaagta
       61 ctagcaaaga ctggatcagt aaaggcacac acaaagttta cagcagaagt atatgtactt
      121 aaaaaagaag aaggtggaag acatacacca ttctttgatg gatatagacc acaattctat
      181 ttcagaacaa cagacgtaac aggagcttgt aagttaccag aaggaataga gatggtaatg
      241 cctggagata acgtaacaat ggaagtagac ttaataaact caatagttgt agaagaggga
      301 ttaagattct caataagaga aggtggaaga acagtagctt caggagttgt tgctacaata
      361 atagagtaat cctttactaa actaatggat ttaatataaa aaaagagggg ggtaactcct
      421 ctcttttttg ttttttgttg acaagtagcg ctaaagcata tatactaaac tagtgccttg
      481 agacagatta acaatcaagt ttaaggttat gatgttgtaa tagaaaataa aattgaaaaa
      541 aacagaaaaa aaacttgaaa aaatgtaaca gatgatataa aatataatag tgtgcttgag
      601 agattaagaa aataataatt aaatcctagt gaaatacgaa ctgatatcga tttaaaagtt
      661 acaacacacc cggagcagtg tatcggtatt ggttgtacgc aacttgaaaa ttaaacacgt
      721 gataaaggag ggaaaacaaa atggctaaga atgaaaaaat aagaataaga ttaaaatcat
      781 atgatcacaa attattagat ttttcagcag gtaaaatagt tgaaactgct aaaaaggctg
      841 gatcacaagt ttcaggacct gtgcctctac caacagaaaa acaagttgta actatattaa
      901 gagctgtaca taagtacaaa gactctagag aacaatttga aataagaact cataaaagac
      961 taatcgacat agctaatcca acacctaaga cagttgactc attaatgaga ttagacttac
     1021 cagcaggtgt agatatagaa ataaaattat aagaacccct aagatattat cctatagatg
     1081 attatcttag aatgattact ctaaaagatg taatccgctg taagaattat aggaggtgct
     1141 aatatgaaag gaatattagg caaaaaagtt ggtatgactc aaatattcac tgataaaggt
     1201 gtagttatac ctgtaacagc tgttgaagca gggcctatgg tcgttactca aataaaaaca
     1261 gttgataaag atggatacaa tgctatacaa ataggttttg aagatgctaa agaaaaagct
     1321 ttaaacaaac ctaaaaaagg acatttagct gctgctaatg ttttaaagaa acatttaaaa
     1381 gaatttagag tagattctgt agaaggatac acagtaggac aagaaataaa agctgatgta
     1441 tttgaagcag gtgcaaaaat agatgttact ggaataagta aaggtaaggg attccaaggt
     1501 ccaataaaaa gacatggaca aagtagaggt cctgaaactc acggttctag ataccacaga
     1561 agaccaggtt caatgggagc ttgttcttac ccaggtagag tatttaaaaa caaaaaatta
     1621 gctggacata tgggaagcgt aaaggtaaca gttcaaaact tagaggttgt taaagtagat
     1681 gctgacaaga accttatatt agttaaagga gctataccag gagctaaagg ttcagtagta
     1741 actataaaag aagctataaa ggtttctaaa taatgactaa cctagagaaa ggaggaataa
     1801 caatgccaaa attaaatgta ctaaatgtta gtggacaaaa cgttggagaa atagaattat
     1861 cagattctat atttggcgta gaagttaatg gacatgtttt atacgaagtt gtaaaaaatc
     1921 aattagcaaa taagagacaa ggaactcaat ctgctaaaac tagagcagaa gttagaggtg
     1981 gcggaagaaa accttggaaa caaaaaggaa caggtagagc aagacaaggt tctacaagat
     2041 ctgtacaatg ggtaggtgga ggagttgctt ttgcacctaa accaagaagc tacaaatata
     2101 cattacctaa gaaggtaaga agattagcta tgaagagtgc tttatcttca aaagttcaaa
     2161 atagtgaagt tatagtatta gatgcattaa acatggatgc tcctaagact aaagaatttg
     2221 ctcaaatatt aaacaatata aatgctgcta aaaaagcttt agtagttata gctgacaaaa
     2281 acgataacgt aataaaatca gctagaaata tagaaggtgt tcaaactgca ttagttaata
     2341 ctatgaatgt atatgatata ttaaaatacg attcatttat aataactaca gatgctgtta
     2401 aaaaagtgga ggaggtgtac gcataatgac taatccacat gatgtaataa taagaccagt
     2461 tgtaactgag cacagtatgg ctgaaatggg tgaaaaaaaa tacacttttg ttgtggctaa
     2521 agatgcgaac aaaactgaaa taaaaaaagc agtagaaaaa gtattcggag ttagtgttga
     2581 taaagtaaat actttaaact acgatggaaa agttaaaaga atgggtagaa ctcaaggaag
     2641 aacatcaagc tttaagaaag cagtagttaa attaactgct gatagtaaag aaatagaatt
     2701 cttccaagga atgtagtatt ataacaaacg aaggagggaa aacagatggc tataaaaaag
     2761 tttagaccaa cttctcctgc cttaagacaa atgacagttt tagtttctga tgaaataaca
     2821 tgtaatcaac cagaaaaatc tcttttagtt aacttaaaga aaaatgctgg tagaaacgta
     2881 catggtagaa taactgttcg tcatagaggt ggaggacaaa aaagaaaata tagaataata
     2941 gattttaaaa gagataaaga tggtatacct gctaaggttg ctactataga atatgatcca
     3001 aacagaactg caaatatcgc attattaaac tatgctgatg gagaaaaaag atatatatta
     3061 gctccagttg gaattaatgt tggagatact atattatcag gattaggtgc tgatataaaa
     3121 ccaggaaact gtttagcatt aaaagatatg ccagttggta ctatcattca taatatagaa
     3181 ttaaagccag gaaaaggagc tcaattagtt agatctgctg gagtttctgc acaattaatg
     3241 gctaaagaag gaaaaaatgc tttattaaga ttaccatcag gtgagatgag attagtaagc
     3301 ataaactgta aagctactat aggtcaagtt ggaaatatag agcatggtaa cgtagttatc
     3361 ggtaaagcag gtagaaaaag acatatggga ataagaccta ctgtaagagg ttctgtaatg
     3421 aaccctaatg accatccaca cggtggaggg gaaggtagat ctccaatagg tagaccatct
     3481 cctgttactc catggggtaa accagctctt ggatacaaaa ctagaaagaa aaataaagct
     3541 tcaaataaac taatagtatc aagaagaact aagtagtaaa tttatttttg ctcggaaagg
     3601 aggaatataa atgtcaagat caactaaaaa agggcctttt gtccatgcaa gacttttaaa
     3661 gaagatagaa gctatgaatg ctagtggaaa taaagaagtt ataaaaactt ggtcaagatc
     3721 ttcaactgta tttccacaaa tggtagaaaa cactatagct gttcatgatg gaagaaaaca
     3781 tgttccagta tatataacag aagatatggt tggacataaa ttaggtgagt tcgttcctac
     3841 tagaactttc aaaggacata aggatgacga aaaatctaat aagagaaaat aattaaatta
     3901 tgactaagaa aggaggaata acaatggaag caaaagctac tgctaaatac gtacgtgtat
     3961 caccaagaaa agcaggccaa atatgtgacc ttgttagagg aaagaatgtt gatgaagcat
     4021 tagcaatatt aaagtttact ccaagaggag cagcttcaat aatagctaag gttgtaaaat
     4081 cagctaaagc taacgcagaa aacaatcacg aaatggatac tgaaaaatta tatatagcat
     4141 caatagttgc taatcaagga ccaacaatga agagattcat gcctagagct atgggtcgtg
     4201 caactacaat aagaaaaaga acttctcata tagaggttgt tgttaaagaa aaaaaataat
     4261 taatagatag gagggaaagt aatgggtcaa aaggttaatc cacacggctt aagggtcggt
     4321 gttataaaag attgggactc aagatggttc gctactgata aaaaagagtt cggaaactta
     4381 ttattagaag accataatat acgtaaattc ttaaagaaaa gattatactc agctggagtt
     4441 gctaagatag aaatagaaag atcagctaac aaaataaaaa tggacttaca cgttgctaag
     4501 cctggtgtag ttataggaag agctggtgca ggaatcgaag cattaaaagc tgaattagaa
     4561 aaaatgacaa agaaaactat aatagttaat atagtagaag taagaagtac agataaaaat
     4621 gctcaattag tagctgaaaa tatagcttta gctatagaga gaagggttgc tttcagaaga
     4681 gcaatgaaac aagctataca aagagcaatg aaatctggtg ctaaagggat aaaagtttct
     4741 gcttcaggaa gattaggtgg agctgaaatg gctagaactg aaggttatag tgaaggaaat
     4801 gtgccactac aaactttaag agcagatata gattatggtt tcgctgaagc tgatacaact
     4861 tatggaaaaa tcggtataaa agtttggata tgtaatggtg aagttttacc aactagagac
     4921 ggtgtaaatc caagagaaga aagcagaaag agcgatagaa gagacaacaa gagagataat
     4981 agaagaaacg atagaagagg aaatgacaga agaggaaatg ataacagagg aaactacaga
     5041 ggacaaagac ctcaaggtgg atcaagacct caaagaactg aaaacaaagg aaattaataa
     5101 tagttaggtt caaggaagga ggaaaaatac tcatgttaat gccaaaaaga gtaaagcgtc
     5161 gtagagttca tagaggaagc atggctgggc aagctcataa gggtaataaa gttacttatg
     5221 gtgagtttgg attagtagca ttagaagctt cttggataac ttctaatcaa atagaagctg
     5281 ccagaatcgc gatgactaga tatataaaaa gagggggaaa ggtttggata aaaatattcc
     5341 ctcataaacc agtaacaaga aaaccagcag agactcgtat gggtgcaggg aaaggttctc
     5401 cagaatattg ggtagctgta gttaagccag gaagagttat gtttgaatta gcaggtgttt
     5461 ctgaagataa agcaagagaa gctatgagac ttgctgcaca taaattacca atcaaatgta
     5521 aatttgttaa aaaagaagat ttagaagtaa agggtggtga ataggatgaa agctaaagaa
     5581 ttaagagatt taacaagcga agagctaatg aacaaattaa acgacttcaa aagtgaatta
     5641 tttagcttaa gattccaatt agctactggt caattagaaa atacagctag aataaagttt
     5701 gttaagaagg atatagcaaa agttaaaact gttcttgctg aaagaaagtt atacgaaact
     5761 agagcttaat ttggaaagga ggctttttaa acatggaaag aggaagaaga aaagttagaa
     5821 taggccgtgt tgttagtgat aagatggata aaacaatagt agtagctgtt gaagaattcg
     5881 tacgtcatcc actatataat aaacgtgtta agagaactaa gaaattcaag gctcatgatg
     5941 aaaagaatat atgtaacatc ggagatagag ttaaaataat ggaaactaga ccattatcta
     6001 aagataagag attcagacta gttgaagttg ttgagaaagt taagtagttt ttgaagaagg
     6061 agggattacg atatgataca acaagaatca cgtctaagag ttgctgataa ctcaggagct
     6121 aaagaacttt tatgtatacg tgttctaggc ggaagtaaaa gaagatatgg taacataggc
     6181 gacgttatag ttgctactgt taaaagtgca acacctggtg gagttgtaaa aaaaggtaag
     6241 gttgttaaag ctgttatagt aagaagcaaa caaggcgtaa gacgtaatga cggaagctat
     6301 atatcttttg atgaaaatgc tgctgttata ataaaggacg ataaaactcc agtaggaact
     6361 cgtatattcg ggcctgttgc tagagagtta agagacaatg aattcatgaa aatagtttct
     6421 cttgctccag aagtactata attaaggagg tgcaatagga catgatgcgt gttaaaaaag
     6481 gtgacactgt tgtagttata gcaggtaaag ataaaggtaa aaaaggttca gttttaaagg
     6541 tatatcctaa aactagcaaa gtgttagttg aaggtgtaaa tgtaataact aaacatcaaa
     6601 aaccaagtgc tatgaaccaa caaggtggaa taataaataa agaagcccca atacacatat
     6661 ctaatgtaat gccatttgat cctgaaacag gaaaaggcgt tagagtaaga tatgaagtaa
     6721 aagatgggaa caaagtaaga gtatcagcaa agagcggaaa agaattataa taaatattgc
     6781 ttgaaaggag ggaccttaaa tggcttctag attacaagaa aaatacatga aagaagttgc
     6841 tcctgcttta atggagaaat ttggatacaa aaacgtaatg gagataccta agttaaataa
     6901 aatagttatt aacatgggta taggtgacgc tagagaaaat ccaaaaggat tagaaaaagg
     6961 cgttgaagaa ttagaaatga tatcaggaca aaagcctgtt ataactaaag ctagaaaatc
     7021 tgttgctaac ttcaaattaa gagaaggaat gccaatagga acaaaagtta cattaagagc
     7081 tgacaaaatg ttctacttca tggacaaatt agtttcagtt tctttaccaa gagttagaga
     7141 ctttagagga gttaacccta atgcttttga tggtagagga aattatgctt taggagttaa
     7201 agaacaatta atattccctg aaatagaata tgataaaata gataaagtaa gaggaatgga
     7261 tataatattt gttactacag caaaaactga cgaagaagct cgtgaattat taaaattatt
     7321 aggaatgcca ttttctaagt aagcaaagga gggattcccg tggctagaaa agcgatggtt
     7381 gttaagcaac aaagaaagca aaagtacgct actagagaat acactagatg tactatatgc
     7441 ggaagaccgc attcagtttt gaaaaaattt ggtatatgcc gtatatgctt tagagaatta
     7501 gcttataaag gtcaaatacc tggtgttaga aaagcaagct ggtagaagct tgattagaat
     7561 ggaaggaggg caacaaaatg acaatgacag atccaattgc agatatgctt actcgtataa
     7621 gaaatgctaa tgttgttaag catgaaactg tagatgttcc agcttctaat atgaagaaag
     7681 aattagctag aatcttatta gaagaaggtt tcataagagg ttatgatgtt atagaagatg
     7741 gaaaacaagg tatcataaga atacaattaa agtacggaca agaaggcgaa agagttataa
     7801 caggtcttaa gaaaatatct aagcctggaa tgagagttta cgctgctaac catgagatac
     7861 caaaagtatt aaacggatta ggaatatcag ttatatctac ttcaaaagga atattaactg
     7921 acaagcaagc tagaaaagaa aatgttggtg gagaagtaat ctgctacgtt tggtaattaa
     7981 tatgaacaat gtaaggaggt gcgaccatgt caagaatagg tgttaagcca ataataatac
     8041 cagcaggtgt tgaagttact atagctgaag gaaatttagt tacagtaaaa ggtccaaaag
     8101 gaactttaac taaacaatta agtgctgagt taaacataaa aaaagaagaa aatacaataa
     8161 tggttgaaag accaactgat aataaaaaac atagatcttt acacggacta actagaactt
     8221 tattagataa tatggttgta ggtgtaaata ctggtttcga aaagaaatta gaattaaaag
     8281 gtgttggata tagagctcaa aaacaaggaa agaaattagt tatgaactta ggtttctctc
     8341 atccagttga gatggaagat ccagaaggaa taactgttga agctccaaac caaacagagt
     8401 taatagtaaa aggtatagac aagcaattag tagggaatta tgctgctaag ataagagctt
     8461 ggagaaagcc agagccatac aaaggtaaag gtataaaata cgttgatgaa gtaatcagac
     8521 gtaaagaagg aaaaactggt aaaaaataat accaaaactt aaacgctaga aaggagtgag
     8581 ctaggtgtta aaaaaggctg ataaaaatgc taatagactt caaagacata agagagttcg
     8641 tagaaaaata agcggtactt ctcaaagacc aagattatgt gtatttagaa gtgctaacaa
     8701 tatatatgct caaataatag atgacacaaa aagagtaact ctagttgctg catcttcttt
     8761 agaagcagaa gttaagagtg ctgtcaatca tacaggaaac aaggaagcag ctaagaaagt
     8821 tggagaatta gttgctaaaa aagctgttga aaaaggaatc actgaagttg tatttgacag
     8881 aggtggatac ttatatcatg gaagaattca agaattagct gaaggtgcta gagaagctgg
     8941 tcttaagttc taatacgaag gagggaaaaa tacatgctac gtcgtaagcc gatagatgca
     9001 ggacaacttg acttacaaga aaaagttgtt gaagtaagac gtgttactaa ggttgtaaaa
     9061 ggtggtagaa atttcagatt tgcagcatta gtagttgttg gagatgaaaa cggacacgtt
     9121 ggtataggtg ctgggaaagc aatggaagta ccagacgcta taaaaaaagc agttgaagat
     9181 gctaagaaaa atctaatagt agtgccaata gttgggacta caattcctca cgaagtacgc
     9241 ggacactttg gtgctggaaa tatattaata atgcctgctg tagaaggtac aggagtaata
     9301 gctgggggac ctgctagagc cgtacttgag ctagctggac taaaagacgt tagagctaaa
     9361 tctttagggt ctaacaatcc aagaaatatg gtaaatgcta caatagaagg acttaattct
     9421 ctaaaaacag ttgaagatat agctaaactt agaggtaaaa aagttgaaga acttctaggg
     9481 taaggaggta gtgtaaaatg gctaaattac aaataaagtt agttagaagt gttataggaa
     9541 ctactcctaa ccaaaaaaag aatgttgaag cgttaggatt aagaaaaaga gaacaagttg
     9601 ttgtaaaaga agacaatgct caaacaagag gtatgataaa taaagtaagt cacttattag
     9661 aagtaactga aatagctgaa taatttttat aaagtagtgc aaggaggtgc aatccatgaa
     9721 gttacatgag ttaaaacctg ctgaaggtgc agtaagagct aagagaagat taggtagagg
     9781 tactgcaact ggacaaggta aaactgcagg acgtggacaa aaaggtcaat ggtctcgttc
     9841 tggtggtgga gtaagagtag gatttgaagg tggacaaatg ccactagcta gaagacttcc
     9901 taagagaggt ttcaataaca tatttaagaa agtttacaca gaagttaatg ttgaagtttt
     9961 aaacagattt gaaaatggaa cagaaataac tgcagaatta ttaaaatcta ctaaaactat
    10021 aagcaaaata ggtaaagacg gaattaaaat cttaggtgaa ggtaatttag agaaagcttt
    10081 aactgttaaa gctgctaaat ttacagcttc agctcaagaa aaaatagaaa aagctggtgg
    10141 aaaagcagag ttagtataat aacctgctaa tctcctagcc agtacaggcg gggtgaatta
    10201 gcgtgctgtc aaaattaaaa caagcttgga agattaaagc agtaagaaaa aaagtaatgt
    10261 atacacttat gatgatcgtg atattcagaa taggtactac tataccagtt ccaggcatag
    10321 acactagtat tatacaaaag atggtaggcg gcaatagtct actttctctg tataatatgt
    10381 ttactggtgg agcatttagt aacttttcac tatttgcttt aggtataagt ccatatatca
    10441 ctgcatcaat cataatacaa cttctaacag taggttttga aagtttagca gaacttcaaa
    10501 aatctggtga agaaggaaag aaaaaaatca ataagtacac taaatataca gcactagctc
    10561 tagcagttgt acaagctttg ggaattacat taggaattgt aagaagtgct ttaatatcaa
    10621 atagtgtgtt ttttatcaca actgttgtaa taacattagt ttcagcaagt atgttagtaa
    10681 tgtggattgg ggacaaaatt actgaaaaag gaatcggtaa tggtagttca gtaataatat
    10741 ttgcaggtat aatatcaaga atacctacag atgttattaa aatatcgcaa caagttaaat
    10801 ctggcgaagt tgcaccttgg gttatagtga ttctagctgt agttatatta cttacagtaa
    10861 caggagttac atttatacaa gaagcaacta gaaagatacc tgtacaatat gctaaaagag
    10921 ttgttggaag aaaaatgtat ggaggacaaa gttctcatat accaatgaaa gttaaccagt
    10981 caggagttat gcctataatt tttgctagtt cacttttagc tttccctcaa acaatagcta
    11041 tgtttatggg tccaaatgct caggcttttg ttcaaaaata cttaagtatg gcaacagaac
    11101 aaggattttg gacatataga tcaattgaga ttctacttat aattttcttc tcatattttt
    11161 atacaactgt atcatttaat acagaagaca tatctaaaaa tatgaaaaat aatggtggat
    11221 ttataccagg tataagacca ggtgagccta ctatggatta tttaaataga attttaacta
    11281 gattaacttt agctggagct actttcttag caataattgc tatggtgcca gctcttacaa
    11341 cacattatat gaaagtaaat atgagtctag ctgggacttc attgctaatc gttgttggag
    11401 ttgctttgga gcttaagaga cagttagagt caaacttagt tatgagaagc tatcaaggtt
    11461 tcttaaaata aaatggagat ggataatatg agaataatat tacttggacc tccaggtgct
    11521 ggtaaaggta ctcaggcggc aggaatagta gaaaaataca atatacctca tatatcaaca
    11581 ggagatatat tcagaaagaa tataaaagag ggaacagaac ttggaaaaaa agctaaagaa
    11641 tacatggacc aaggtttatt agtaccagat gagttaactg taggtttagt tactgataga
    11701 atatctcaag aagattgtaa aaatggattt atgttagatg gatttccaag aaatgtagca
    11761 caaggagaac atttagatat cttcttaaaa aatgctggta tatcactaga taaagttgtc
    11821 aatattgaag ttgataagag tatattagtg tctagagcag ttggtagaag aatatgtaag
    11881 tcttgtggag ctacttacca tgttgagttt aatcctccta aagtagaagg tgtatgtgat
    11941 gtatgccaag gagaattata tcaaagagct gatgataatg aagaaactgt atctaagaga
    12001 atacaagttt atctagatga aactaagcct ttagtagatt attatagcaa acaaggtata
    12061 atagcagata taaaaggtga tcaagcaata gataaagtat ttgaagatat tgtcgcagcc
    12121 ttaggaagtg gaaaataaat gattatcttg aaatcaaaaa aagaaataga acttttaaga
    12181 gaagcaggta aaatagttgc tgacactcat gaagttttaa gaaaagctat ttctccggga
    12241 atatctactt tagaattaga taaaatagct gaagagaata taagaaaata caatgcagaa
    12301 ccttctttta aaggatatgg aggttttcca ggaagtatat gtgcttctat caatagagag
    12361 gtagtacatg gtattccagg agaaactata ttacaagaag gtgacattgt aagtttggat
    12421 ataggagcct attataaagg atatcatggt gattctgcga aaactcacgg agtaggcatg
    12481 atatctgaag aagataggaa attgatagaa gtaactagag aaagcttcta tgaaggaata
    12541 aaatttgcta aattaggata tagactttca gatatctcac acgcagtaca aacacacgtt
    12601 gagaaacatg gtttctcggt agttagagat ttagtgggtc atggagttgg agcaaatctt
    12661 catgaagacc cacaagtacc taattatgga ctcccaggaa aaggaccaag acttagagaa
    12721 ggaatggtta ttgctataga gccaatggtt aatgcaggtc gttatcatgt aaagactcta
    12781 tcagatgggt ggacgactgt tacaatagat ggaaaaaaat cagctcatta tgagcatacg
    12841 atagcaatta ctgaacatga acctttgata ttgacaaagt tgtaatttaa aaagtaggtg
    12901 aaaaaagtgc tatcagataa tttaagtata ggtcaagttg ttaaagtttc attaggacga
    12961 gataaaggaa atttattctt tgtagtcaaa ataattaata atgaatatgt attaatagct
    13021 gatggaaaaa agagaaaact tgacaaacct aagttaaaga aagtgaagca cttaaaaaaa
    13081 tataatttta ttaatgatga agttagaaaa agagtagtat ctggacaaga gattacagat
    13141 tcttttttaa gagctgaact tactaagtta aattagataa tttaacttat tgaaatggag
    13201 ggctggttag ttaatggcca aaaaagatgt tatagaatta gaaggtacag tttcagaagc
    13261 tttacctaat gctatgttca aagttaaact agaaaatgga catgagatat tatgccacat
    13321 ttctggaaag ctaagaatga acttcataag aattcttgaa ggtgacaagg tgaatgttga
    13381 actttctcca tatgacctta caagaggaag aattacttgg cgtaagaagt agactatatt
    13441 aatatttagt ctaaggaggg attaataatg aaggttagac catcagtaaa accaatatgt
    13501 gaaaaatgta aagtaataaa aagaaaagga aaagtaatgg ttatctgtga aaatccaaag
    13561 cataagcaaa agcaaggata agaaattatt actagcattt tgttaaattt tatagtataa
    13621 tactatattg tgatgttaac aaaagaacgt taaaatcgtt gaacaatctg gcgtaggatt
    13681 ggcatatgat gtgaagtttt aaacactaaa aactatgtgt aggaggtgcg atcatggcaa
    13741 gaatagctgg ggtagattta cctagagaaa aaagagcgga gataggctta acttatatat
    13801 atggtatagg taaagcaact gctaacgaaa tattagctaa ggctgagata aatccagata
    13861 ctagaataaa agatttatca gaagatcaag ttaatgagtt aagaaaagtt atagatgacg
    13921 atttcttagt tgaaggtgac ttaagaagag aaattgcttt aaacataaag agattaagag
    13981 atataaaatg ttatagagga ataagacacg ctaaaggtct tccattaaga ggacaaagaa
    14041 ctaagactaa tgctagaact agaaaaggtc ctagaaaaac agtatctcgt aaaaagaaaa
    14101 aataaataaa taataactag atgaaggagg gaaaaggaaa atggctaaac caaaaaagaa
    14161 agttacacgt attagaagaa gagaacgtaa aaatatagaa cgtggtcatg ctcatataca
    14221 atcaactttc aataatacaa taataacttt aactgacgtt cacggaaatg ctatatcttg
    14281 ggcaagttct ggacaattag gattcaaagg atcaagaaaa tcaactccat ttgcatctca
    14341 aatggctgct gaaacagctg caaaagctgc gatggaacac ggactaaaaa gtgttgaggt
    14401 attcgtaaag gggccaggtt caggaagaga agctgcaata agagctttac aagcaactgg
    14461 actagaagta actatgataa aagacgttac tccaatccca cataacggat gcagaccacc
    14521 aaagagaaga agagtgtaat taataagagt acaataggag gtgtagataa atggcaagat
    14581 atacaggtgc atcatgtaga caatgccgta gagagggaat gaaattattc cttaaaggtg
    14641 atagatgtta tacagacaaa tgtgctatag taaaaagaaa ctatgctcca ggtcaacatg
    14701 gccaaggaag aaagaaagtt tctaactatg gattacaatt aagagaaaaa caaaaagtta
    14761 aaagaatata tggagtttta gagactcaat ttagaaattt atatgaacgt gctgaaaata
    14821 tgcctggtaa agcaggtgag aacttattaa gtttattaga gagaagatta gataatgtag
    14881 tttacagaat gggactagca tcttctagaa aagaagctag acaattagtg actcatggtc
    14941 atttcacttt aaatggaaat aaagtagaca taccttcatt aatagttaag gttggagatg
    15001 ttatagaagt taaagagaaa tcaagatctt ctgcaaaatt caaaaattta gtagaagtta
    15061 actcaagaat agctcctaag tggttagaag ctaatgtaga aggaatgaca gcaaaagtag
    15121 ttggtgttcc aacaagagaa gatatagatc ttgagatagc agagcactta atcatagaac
    15181 tttactctaa ataataagca cacttttaaa aattatttta aaattttgtt taccctcagt
    15241 ggattactga attttaagga gggttttgtc catgatagaa atagaaaagc caaaagtaga
    15301 tatagttgag cttagcgaag actatagata tggtaagttt gttatagagc ctctagaaag
    15361 aggatatgga ataactatag gtaacgcatt aagaagaata ttattatcat cattaccagg
    15421 tgtagcagtg aatgctataa aaatagatgg agttcttcat gaattttcaa caatacctgg
    15481 tgttaaagaa gatgttactg agataatatt aactttaaaa gagctttcag caactataga
    15541 tggtgaagga agtagaacac ttaaaataga agctcaagga ccatgctcta tcacaggtgc
    15601 agatataatc tgtcctccag atgttgaaat attaagtaaa gatttagcaa tagctacatt
    15661 agatgataat gctaaactta atatggagat atttgtagat aaaggtagag gttatgtttc
    15721 tgctgaagaa aataaaacag agaatgttcc aataggtgtt ttacctgtgg attcaatata
    15781 tactcctgtt gagaaggtta gttatcatgt ggaaaacaca agagttggtc aaaaaacaga
    15841 ttatgataaa ttagtattag aagtttggac taatggtagt ataaatcctc aagagggaat
    15901 atcattagct gcaaaggtat tagttgagca tttaaactta tttatagact taactgaaca
    15961 tgtaagtagt gttgaaatca tggtagaaaa agaagaagat caaaaagaaa aagttcttga
    16021 aatgactata gaagaattag atttatcagt tagatcatat aactgtttaa agagagcggg
    16081 aattaataca gttgaagaat tagctaataa atctgaggat gatatgatga aggttagaaa
    16141 cctaggtaag aagtcattag aagaggtaat acaaaaacta gaagaacttg gattgggatt
    16201 aaaaccaagt gaagaatagc gagcaaagga gggataagaa tggctaagta ccgtaaatta
    16261 ggacgtgaaa cagctcacag aaaccttatg ttaagaaact tagtaacttg cttactaaga
    16321 agtggaagaa tagaaactac agtgactaga gcgaaagaaa ctcgtagaat ggctgaaaag
    16381 atgataactc ttgctaagag aggagatctt catgctagaa gacaagtttt agcttatgtt
    16441 atggatgaaa cagtagttaa taacttattc acagatttag ctccaaaata tgctgagaga
    16501 aatggtggat acactagaat aataaaaata gggccaagaa aaggcgatgc tgctgaaatg
    16561 gcttttatag aattagtata gtaaggaaag gattaggctt gatggcttaa tctttttttt
    16621 atttttttga ctaaggtatg atataataat gtgtaaaatg atttttataa gttattgctt
    16681 actaaaagga gtatgagtta atggataata tagtaaaggt aaataatatt tcgtttgagt
    16741 atattacaga tgaagcaaaa cttaaagcaa tagataattt aagcctagat gttaaaaaag
    16801 gagaatttgt tgcgataata ggacataatg gttctggtaa gtctacttta tctaaaaact
    16861 taaatgctat tcttatgcct actgaaggaa atattcttat tgatgatatg gatactaaag
    16921 aagaagaaag attatgggat ataagacaaa ctgcaggcat ggtatttcaa aatccagata
    16981 atcaaatagt tgctactata gtagaagaag acgttgcatt tggacctgag aacttaggta
    17041 tagaaccaaa agaaataaga cgaattgtag aggagtcttt aaaaagtgta ggtatgtatg
    17101 atttaagaga tagacagcct catttgttat caggaggtca aaagcaaaga gttgcaatag
    17161 caggaattat tgctatgagg cctaaatgta taatatttga tgaagcaaca gcaatgttag
    17221 atccatctgg aagaaaagaa gttatgaaaa caataaaaag acttaataag gaagaaaata
    17281 taactgttat acatataacg cactttatgg aagaagcagt agaagctgat agagttgtag
    17341 ttatggaaaa aggaaagaaa atcttagagg gaactcctag agaagtattc agtaaaataa
    17401 agatgttaaa ggaaatcggt ttagatgtac cttgtatgac agagttatct agtttattaa
    17461 tagaagaagg tataaatatt agtagtgata tattaactgt ggatgagatg gtgatggaat
    17521 tatgtcaatt atagtaaaga atttaacaca tatatataat gaagggatgc cttttgcaag
    17581 taaggcactt gatgatgttt cttttgagat taaagataga gattttgttg gtcttatagg
    17641 tcatacaggc tcaggaaaat ctacattaat acaacattta aatggattac taaagccttc
    17701 ctcaggagaa atatttataa atgattttaa tataacagat aaaaacttga atttaactga
    17761 gattagaaaa agagtagggg ttgtatttca atatccagaa taccaattgt ttgaagaaac
    17821 gattgataaa gatatagctt ttggaccctc taatttaggc ttagaggagt ctgagataca
    17881 taacagggta aaagcatcaa tggaagctgt aggacttgat tatgagggat ttaaagacaa
    17941 atctcctttt gaattatctg ggggacaaaa gcgtagagta gcaattgctg gagttatagc
    18001 catgaaccca gaagttctca tattggatga accaactgct ggtcttgacc ctggtggaag
    18061 agatgaaatt tttaacttaa taaaagactt acatgaaaaa aagaatatga ctataatact
    18121 atcatcacat agtatggatg atatggcaaa gttagcaaaa actttaattg ttatgaatca
    18181 tggtagcgta gaatttatgg gaactcctag agaagtgttt aaatcaaatg ctagtaaatt
    18241 aaaagatata ggattagata ttccacaagt tttagaactt gcattgaaat tgagagaaaa
    18301 aggctttgac atcagtgagg atatattgac tttagaagaa gcaaaacagg aaatattaaa
    18361 agttgtgaga ggacgaggat tatgttaaaa gatataacta tagggcaata ctacccaaca
    18421 agttctgcta ttcataaatt agatccaagg ataaagcttg tagcgacaat tgtatttatg
    18481 gtatctatat ttgtagtaaa taaattttgg ccttatatag tagttttatt atgtttatta
    18541 gctatgataa aattggctaa tataccagtc aaatatattg ttaagggtgt taaacctctt
    18601 aaatggatta ttttgtttac atttcttata aatatttttt tcttaccagg tgatgaaata
    18661 tggtcatttg gatttttagc tattacaaaa cagggtctaa gacaagcaat ttttatggca
    18721 ataagattaa tatttttagt agttggtaca tcattgctta ctttaacaac ttcaccaata
    18781 gaattaactg atggaataga gagattgttg aatccattta agaaaattgg tttgccagtt
    18841 catgaacttg caatgatgat gacaattgct ttacgtttta ttcctacatt gttagatgag
    18901 acagacaaaa taatgaaggc tcagatgtct agaggtgcag attttgaaag taagaatctt
    18961 ataaatagag caaagaattt agtaccactt ttggtacctt tatttgtaag tgcatttaga
    19021 agagctgatg aattggctat ggccatggag gccagatgtt acagaggtgg acataatagg
    19081 actaagatga gagagtctgt tatatcaaga agggattata tggcatgtgt atttcaggtt
    19141 gtttatctgg gagcaattat agctactaga tttatagcaa tttaattaat aagttataga
    19201 tataatgagg taaagtatga gaaatataaa aattaaaatc caatacaatg gtaagaatta
    19261 ttgtggatgg caaaagcaac ctgattcttt agggatacaa ggtacaattg aaagggctat
    19321 atatgatata acaaaagaag aaaccagtct tatagggtct ggtagaactg attcaggagt
    19381 tcatgctatt ggtcagattg caaattttaa aattaattca ggtataagta tagaaagtat
    19441 accaatggca ctaaatgcca agttgccaaa agacatatca gttatagaag catgtgaagt
    19501 aaatgatgat tttcactcca gatacagtgc aaaaggtaaa acatataaat atttagtata
    19561 taatagcaag tttagaaatc caatacttag tgagatatca tatcaagtaa aatatgaact
    19621 tgattttgat aaaatgtgtt cagaagcaaa aagtttatta ggaacacatg attttaaagg
    19681 ttttatgagt tctggttcat ctgtaaaaga tacagttaga acgatatatg atattgatat
    19741 aagtaaaaaa gatgacttga ttacttttga gattagtggt aatggttttt tatataacat
    19801 ggtgaggatt attgttggaa cacttgttga tatgggtcgt ggcagaatta acgaaccatt
    19861 tttagatata atacaatcaa aaactaggtc aagatgtgga catacagctc cagcacaagg
    19921 attatttctc aaaaaagttc attattaact tgacacacca ggctacatgt attaaaatat
    19981 atgagaatgt gttaataagt ccacttgccc cggacttgac ataaacggta aaaaaatttt
    20041 atgaaaagta gttaaggagg gacagttatg aaaagttata tagctaagcc agctgatgta
    20101 caaagaaaat ggtacttagt tgatgctgaa ggaaaaacat taggtcgttt agcaacagaa
    20161 attgcgacag tattgagagg taaacataaa ccaacattta ctcctcacgt tgatggtgga
    20221 gattttgttg ttgtagtaaa tgcagaaaaa atagttttaa gtggtaagaa attagatcaa
    20281 aaatattaca gataccatac tggttatgta ggtggattaa aagaaatatc ttacagagat
    20341 atgatggata agaaaccaga agaagttata tcacatgctg taagcggtat gttacctaaa
    20401 aataaattaa gaagcagaat gatgactaga ttaagagtat ttgcaggtgc tgagcacact
    20461 catgcagctc aaaatccaga agttttaaac tttaaataag attaataggt gaaaggagga
    20521 gtttataatg gctaacgttc aatattatgg aactggaaga agaaaaagtt ctgttgctag
    20581 agtaagacta gttgcaggtg aaggaaatat attagtaaat ggaagagcat tagaaaatta
    20641 ttttaattat gagacattaa taagagatgt taaacaacca ttagttttaa ctggtaatga
    20701 aaataaatat gatgttatag taaaagttga aggtggagga ttcactggac aagctggagc
    20761 tataagacat ggaatatcta gagctttatt aaaagctgat ttagatttaa gacctgcttt
    20821 aaagaaagaa ggtttcttaa ctagagatgc aagaatgaag gaaagaaaga aatacggatt
    20881 aaaagcagca agaagagctc cacaattctc aaaaagataa ttacttattt ttttggaaaa
    20941 gcaaaatcct ttatttactg ttattcagaa agtattggta ttttaaaaat gttgggttaa
    21001 gttaattatt gatatataat aaaataataa gatatcttat taggatgttt ttcattaaga
    21061 agaacatcct ttttattttg actatttaat aaaaaacata tgctaataag atttaaattt
    21121 tatttttata atattgtaat ttaaaagttt atataaggtt atatatttta agatattatt
    21181 taacaatata aattctgaat atacgttatc aaagtttata atataaacta agtataattt
    21241 attgtatagt attgaatgtt agataaacat agtgaattaa ataggggcag aaatataata
    21301 tcattacata ataatatatt aataccaata aataaagata tatcaatatt aaaaaaattt
    21361 aaatgtttgt actaatatat ggaatattat agtgttttta taagtataca tatacagggt
    21421 gatgttgtga gaaagtacat aaaacatata atttttagtt ttgcaatgat atgtctagta
    21481 gtagtatcca tatttgaaat taaaaatatt tctgaagatg ttatcaagta tatgccagta
    21541 acaaacaaaa ctataatttt agatgctggt catggaggca ttgatccagg tgcattaaat
    21601 aaggataaga gtacatctga aaaggatatt aacctagcaa taacacttaa gcttagagag
    21661 cttatagaat caagtggtgg ccttgtaata ttaactcgag aagatgacag tagcctttat
    21721 aaagaagaaa ataataaaac tacaagacaa aaatataatg agaatttgaa aaatagaaaa
    21781 gaaataatat ctaattctaa tgccaatatg tttgtctcta tacatcttaa tgcatttgaa
    21841 caatcaaaat actatggagc tcaaactttt tatcctaaag acaaacaaga cagtaaagaa
    21901 ttatcgaagt gtattcaaga agaacttaaa agagtagtag ataagacaaa caacagagaa
    21961 gtcaaaccaa gggatgatat atatcttttg aaagaaaata atattccatc agtactgata
    22021 gaatgtggtt ttttatcaaa tgaaaaagag tgtaaactct taactgatga aacatatcaa
    22081 gaaaaaatag catgggcaat ctacatagga atacaaaaat atttaagttg aaataactat
    22141 aaaaataggt ctaaatatgt aaatagcttg tattaaagca gttaaaatgc attaatatag
    22201 gctattttta ttttgacaaa aaaatattta aaataaaagt taaaaagttg ttgacttaga
    22261 ataatataga tgatattata tatgagtgcc caaaaggagc accaaaataa gac
//
LOCUS       DAEPHU010000068        21822 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 01A10CD0081
            SAMN05941466-rid12468953.denovo.068, whole genome shotgun sequence.
ACCESSION   DAEPHU010000068 DAEPHU010000000
VERSION     DAEPHU010000068.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941466
            Sequence Read Archive: SRR6291087
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 21822)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21822)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068158.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 22:43:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,892
            CDSs (total)                      :: 3,805
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 87
            rRNAs                             :: 8, 1, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 55
            CDSs (without protein)            :: 55
            Pseudo Genes (ambiguous residues) :: 0 of 55
            Pseudo Genes (frameshifted)       :: 21 of 55
            Pseudo Genes (incomplete)         :: 28 of 55
            Pseudo Genes (internal stop)      :: 16 of 55
            Pseudo Genes (multiple problems)  :: 8 of 55
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21822
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941466-rid12468953.denovo.068"
                     /strain="01A10CD0081"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            149..1747
                     /locus_tag="KR231_002819"
     CDS             149..1747
                     /locus_tag="KR231_002819"
                     /EC_number="3.6.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative manganese-dependent inorganic
                     diphosphatase"
                     /protein_id="HBH0005181.1"
                     /translation="MSLLVFGHKNPDTDSICSAISLAHLKNKLGIKATAYALGDIRKE
                     AKYALDYFKVDAPEILDNVRIQVRDLNYDKVVPLTPTSSILEAYNLMDEKNVKTLPVT
                     YDDGTFAGIITMKEIAKNLLHQHFTTIHTSLSNICKNLNGTILVDCGEDIKGRVVTLS
                     FGMETLIETLKEGDIAIVGDRYDSIEYAIDTKVKLLILTNHTEISKDLLALAKINGVS
                     VVSVESDNYKTSNVINQCSFLDSIEATENLITFKEDDYMDEIKEIMLETNFRSYPILD
                     DDNKFLGLVSKGHLLNPSKKNVVLVDHNEYAQSADGIEQANIVEIIDHHKLGGISTDV
                     PMSFRVMPVGCNSTIIYQMYKENNVEIPYEIAGLLLSAILSDTLLFKSPTTTDMDKKA
                     CEELSKIAKVDMEKYAMDMFKCGTSLDEYTIEEIVNMDFKEFNMSGHRVGIGQVFTLD
                     IDSIFAKKDEFLSYINSTDYDKLILSVTDIIKEGSYLIYKAEDSLIANAFGVEGVQGT
                     FAPGVVSRKKQLVPNLTTAIKNFK"
     gene            complement(1982..4063)
                     /gene="bclA1"
                     /locus_tag="KR231_002820"
     CDS             complement(1982..4063)
                     /gene="bclA1"
                     /locus_tag="KR231_002820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="collagen-like exosporium glycoprotein BclA1"
                     /protein_id="HBH0005182.1"
                     /translation="MRNIILYLNDDTFISKKYPDKNFSNLDYCLIGSKCSNSFVKEKL
                     ITFFKVRIPDILKDKSILKAELFIHIDSNKNHIFKEKVDIEIKRISEYYNLRTITWND
                     RVSMENIRGYLPIGISDTSNYICLNITGTIKAWAMNKYPNYGLALSLNYPYQILEFTS
                     SRGCNKPYILVTFEDRIIDNCYPKCECLPIRITGPMGPRGATGSTGPTGVTGPTGSTG
                     ATGSIGPTGPTGNTGATGSIGPTGVTGPTGSTGATGSIGPTGVTGPTGNTGVTGSIGP
                     TGATGPTGVTGEIGPTGVTGPTGVTGSIGPTGATGPTGATGVTGEIGPTGATGPTGNT
                     GVTGATGPTGNTGVTGVTGATGPTGATGVTGEIGPTGATGPTGEIGPTGATGPTGATG
                     VTGEIGPTGVTGPTGEIGPTGATGPTGVTGSIGPTGATGVTGEIGPTGPTGVTGSIGP
                     TGATGPTGNTGVTGVTGPTGATGPTGVTGEIGPTGATGPTGVTGEIGPTGATGPTGPT
                     GNTGATGSIGPTGVTGPTGATGATGVTGPTGPTGATGNSSQPVANFLVNAPSPQTLNN
                     GDAITGWQTIIGNSSSITVDANGTFTVQENGVYYISVSVALQPGSSSINQYSFAILFP
                     ILGGKDLAGLTTEPGGGGVLSGYFAGFLFGGTTFTINNFSSTTVGIRNGQSAGTAATL
                     TIFRIADTVMT"
     gene            complement(4741..5265)
                     /locus_tag="KR231_002821"
     CDS             complement(4741..5265)
                     /locus_tag="KR231_002821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HBH0005183.1"
                     /translation="MENKNPIVTIEMENGKEIKIELYPNIAPNTVKNFVSLVNEGYYN
                     GIIFHRVIPGFMIQGGCPNGTGMGGPGHSIKGEFSGNGFTNNLKHERGVISMARTMAP
                     NSAGSQFFIMHKNSPHLDGQYAGFGRVIEGMDTVDEIASVRTDSADKPQTPQIMKSVT
                     VETFGIDYSDVEKN"
     gene            complement(5330..6082)
                     /locus_tag="KR231_002822"
     CDS             complement(5330..6082)
                     /locus_tag="KR231_002822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="patatin-like phospholipase family protein"
                     /protein_id="HBH0005184.1"
                     /translation="MKLGLCLEGGGAKGAYQAGVVKALYDGGINKFYSISGTSIGAIN
                     GYYLYTGNVDNLEKMWTNIKDIQNGNVKIVNNTVDNSPAIDNLRELDDSNIEEMNFYV
                     NYVEVDNKVVSEKIVDVSKMPRNEAIISISYSGLLPSNPNATLGFKEQFVKDVQEGIY
                     DGFKLDGGLIRSALIEPLIGDNVDKIILISTKYNYELPEDIKKVYDEDKIIVVRPNTQ
                     FAPKDTLNFDDEFCKTIYQEGYEIGKNILDRL"
     gene            complement(6113..7411)
                     /locus_tag="KR231_002823"
     CDS             complement(6113..7411)
                     /locus_tag="KR231_002823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M18 family aminopeptidase"
                     /protein_id="HBH0005185.1"
                     /translation="MDSINFAKNLIDFIYDSPSSFHAVKSTKEILDKNGFEELVLNQR
                     WNLRVGGKYYVTKNLSAIVAFVVNSEDIERDGFRIIGSHSDSPTFSIKPNAEIEAEKS
                     YLKLNTECYGGAILSTWLDRPLGIAGRVVLKGDSILKPNERLIDFKKPICIIPNLAIH
                     LNRSINDGHSYNKQKDMLPLVGMLNDTLEKDNFLIKQIASNLDVNMDDIIDFDLFLYE
                     FEKGSLIGANDEFISIGRQDNLAMVHASLNALVNTKGQHGVNVMAVFDNEEVGSSTKQ
                     GADSNMLLNILERICISMGKDREGFFESIYSSFMISSDLAHAIHPNIPEKHDPTNKPI
                     MGKGPVIKINASQAYTSDGYSIAIYKNICREANVEYQEFVNRSDERGGSTIGPISSTH
                     IDIPSVDVGSPILAMHSIRELGNVEDHYSIYKTFSKFFEI"
     gene            complement(7428..9692)
                     /locus_tag="KR231_002824"
     CDS             complement(7428..9692)
                     /locus_tag="KR231_002824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3553 domain-containing protein"
                     /protein_id="HBH0005186.1"
                     /translation="MNLDTLNPAQREAVEKTEGPVLILAGAGSGKTKVLTTRIAYLIE
                     DKGVQAPNILAITFTNKAANEMRERVEQNIGPETKDMWISTFHSCCVRILRKDINKIG
                     YNRSFVIYDSADQVTLVKDCLKELNLSDKVFEPKAVISAISGAKDKLYTPKQFKDINM
                     ADNRMVKIADIYALYQDRLKRNSALDFDDLILKTVELFKANDEVLAYYRSRFRYIMVD
                     EYQDTSKAQYELIKLLAREHQNICVVGDDDQSIYGWRGADIRNILEFEKDYDNVHVVK
                     LEQNYRSTQVILDAANKVISNNIERKRKKLWSEKKEGELIKIQLTGSEIEEADFIADS
                     IAQIARKENRPYKDFAVLYRANAQARPVEDALNRSQIPYNIYGGTKFYERKEIKDLLA
                     YLRVIQNPQDDISIKRIINVPRRGIGLRTIEKIEDRANLKQESIYSVLIDIETNSDIS
                     TKARASISGFVDIIGTLRTIKEVYPVSKLIEKVLDTTGYMDELVEIRNKNEKDLTGKG
                     EEAQDRIDNLREFISIALEFESSNDDTYENKDLETFLTSIALTSESNDEEDNDRVSLM
                     TIHTSKGLEFPVVFLTGMEEGLFPISRAIKSMSDSQIEEERRLCYVGITRAKEELYMS
                     LTEKRTLYGKTNVAIASRFMEELPEECIERLYKVKKELSYSKASYNMLDKYTKKYMST
                     ISKSKVADKVNATIKDSNKETNPDDIKLGSKVHHPKFGVGTVVSIIGTDVTIAFDQQG
                     IKKINKEYTTLNIL"
     gene            complement(9947..10765)
                     /locus_tag="KR231_002825"
     CDS             complement(9947..10765)
                     /locus_tag="KR231_002825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009904855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor ABC transporter
                     ATP-binding protein"
                     /protein_id="HBH0005187.1"
                     /translation="MFKINNLTYQYEKNTNALLNINMDFSKGNVIGIIGSNGSGKSTL
                     FMNLMGILKPTSGEILFKEEKLKYDKRSLYNLRKNVGIVFQDPEKQIFYSKVYDDIAF
                     AMRNIGMDEKTIKERINKALVAVNGIDFIDRPVHFLSYGQKKRVAIASVIAMENEIVL
                     LDEPTAGLDPVSTRSIVDIIKGLNKNNIKIVISSHDMNLMYEICDYIYVLDKGILIDE
                     GKAENVFINENNIIQAGLESPWLVKVHRNMNLPLFKKEEDLYKYWKERELNTNK"
     gene            complement(10758..11456)
                     /gene="cbiQ"
                     /locus_tag="KR231_002826"
     CDS             complement(10758..11456)
                     /gene="cbiQ"
                     /locus_tag="KR231_002826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalt ECF transporter T component CbiQ"
                     /protein_id="HBH0005188.1"
                     /translation="MLIIDKYAYTNRLSKVNPNKKVAIGVIFLIASMVIQNIFILSGI
                     MILMSILVVCVAGIDLKNYLKLLRIPMYFLFLSIGITLVNISFNKADLLYSFEFFSFN
                     VGISKASIDMSIHVLFRAMSCLTCVYFCILTTPFNQLIFFFKKLHLPDTFVELSMLIY
                     RFIFIFLEEFSEIYKSQELRFGYINLKTSYKSLGILGSMLYKRLMTRYDDMCISLDIK
                     LYDGKFHIVGDNDV"
     gene            complement(11459..11737)
                     /locus_tag="KR231_002827"
     CDS             complement(11459..11737)
                     /locus_tag="KR231_002827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor ABC transporter
                     substrate-binding protein"
                     /protein_id="HBH0005189.1"
                     /translation="MSAKTKTNILLLLLVVALIIFPLLVNSGAEYGGADGQAESEITK
                     INPNYKPWFSSPYEPPSGEIESLLFSAQAALGAGVIGYILGLQKGKRS"
     gene            complement(11727..12479)
                     /locus_tag="KR231_002828"
     CDS             complement(11727..12479)
                     /locus_tag="KR231_002828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006440549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor ABC transporter permease"
                     /protein_id="HBH0005190.1"
                     /translation="MKQNIKLGVIAALMLIILTPVTSNAMHIMEGYLPVKWSIAWGVI
                     FIPFFLFGLKSIGKIVKQDPKKKVLLALCGAFVFVLSALKIPSVTGSCSHPTGVGLGA
                     IMFGPSVMFVLGTIVLIFQALLLAHGGITTLGANAFSMAIIGPIVSFLIFKALKKKDG
                     NNAIPVFLAAAIGDLATYTITSIQLALAFPDPSGGVMASAIKFLGIFFMTQIPIAIAE
                     GILTVIVYNLITENGEKSILENNDKGVKANEC"
     regulatory      complement(12661..12853)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00174"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="cobalamin riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="adenosylcobalamin"
                     /db_xref="RFAM:RF00174"
     gene            complement(12985..14757)
                     /locus_tag="KR231_002829"
     CDS             complement(12985..14757)
                     /locus_tag="KR231_002829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitric oxide reductase activation-like protein"
                     /protein_id="HBH0005191.1"
                     /translation="MKWIYDDYEFENRANNLSWTIAGDYNESIDISEKDYSSKEIGLY
                     FAIIAGARRKYVDWDIVKKYLTNRIRKGYNKDIILGLIQVILNTIVEEKVIKDRPGIE
                     DIRRNAYKDIVSRFTKIHNDNIMDKIKYTFVLYSMDKHPALDSMTRRIVNDIRNIDTN
                     QDIMEILKALDVIYLTYFEYILNGEENSLIDENNVESVEVNFDTFADFMYEELYSDEE
                     ENIIESDIDSISSSMLVEGVGDFDDSKCSNSADRVIYVDEDTANKIYSKIEHYYGKTY
                     LSKGEIKKIETQNCRNVHEGCRIHFTDGVLRSECNNVFQLKYVTRQKENNLGKFREHA
                     RMYRQQIKRLKESLSRILIEENAKSRVYSDCGTILANRAWRVGRSNNNKIFYKDIENE
                     KGKYVIDILLDASGSQSRNQGNVAIQAYIIANALTEVGIPNRVMGFSSFLDYTILKRF
                     KDYDDSIKNSENIFEYFCAGNNRDGLAIKSICSGLINRDEENKILIVLSDGRPNDVKI
                     GKSSERTLRGEKAYRGIVGLRDTANEVRKARKQNILVLGVFTGKESELEAERLIYGND
                     FIYSRDITRFSDVVSMYLKKIIRN"
     gene            complement(14771..15700)
                     /locus_tag="KR231_002830"
     CDS             complement(14771..15700)
                     /locus_tag="KR231_002830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HBH0005192.1"
                     /translation="MDIIDNLRVQGVDEKLIEDVLYFRNYYGLEKDLEYRVTKSKTYF
                     YGKDILSMCIAAILEEENILLSGPKATGKNLLADNLGEIFNRPQWNTSFHINTDSSTL
                     IGTDTFIDNEVKLRRGSVYECAINGGFGVFDEINMAKNDAIVVVHSALDYRRIIDVPG
                     YERVNLHPATRFIGTMNYEYAGTKELNEALVSRFMVIDIPPIEEDKLMMILKNEFSDA
                     DEEKLIHFAGIFLDLQLKSQNGEISSKAIDLRGLMASLKTIRRGLKPTLAINMGLTGK
                     TFDVYEKEMVGDVIKTRIPNKWESIDVFPISHI"
     gene            15929..16117
                     /locus_tag="KR231_002831"
     CDS             15929..16117
                     /locus_tag="KR231_002831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBH0005193.1"
                     /translation="MEYMSCPEVAKKWGISERRVQKLCEESRIPGVSKLGYMWLIPKN
                     AEKPVDGRTKRRKEVQYE"
     gene            16110..16811
                     /locus_tag="KR231_002832"
     CDS             16110..16811
                     /locus_tag="KR231_002832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBH0005194.1"
                     /translation="MNSVLIIDDDKELCALMKKCVEQENLSAITAHGGAEGLHLVDKN
                     RHTLSLVILDIMMPDIDGFQVLKKIRETSNIPVIMLTAKNDEDDKVSGLRLGADDYLT
                     KPFSINELMARVNSLIRRYTMLNPAFITDTDFIIINGMIIDKTNRIVSVNNIPVQLTS
                     KEFDLLAFLASNKGRVFTKKQIYTQVWEEEYAFDDSNIMSFISKLRKKIEPDPNHPFY
                     ILTVRGVGYRFNKEA"
     gene            16813..17736
                     /locus_tag="KR231_002833"
     CDS             16813..17736
                     /locus_tag="KR231_002833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBH0005195.1"
                     /translation="MNTSVYLLLILALSLIIIAYLVSVLLRVRIQLTLIKDALEDIKN
                     GNLNRRILTDENDITKQICYDINEIAINSQFQLIQQKQSEQAYKQLMTSLSHDVKTPL
                     ASLVGYLEAVESKIVVGEEKDEYIHVASNKAHYLKNFVENLFEWVKLDSKEQVFHFDI
                     FDLNELSRNIISDWIPVLESSHFEYEFDIPEIEYFLRIDANAYTRIINNLLQNIITHS
                     SGNKMTLRIFENKEQAQIIITDNGKGISSDNLPHIFERLYQCDHSRASKGNGLGLAIA
                     KELINAHKGNITANSTPGMGTEFTILLPKAL"
     gene            17893..18816
                     /locus_tag="KR231_002834"
     CDS             17893..18816
                     /locus_tag="KR231_002834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019639192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH0005196.1"
                     /translation="MNDFVIETKQLTKIYGNQTVVDKVNLHVKKGRIYGLLGRNGAGK
                     TTIMKMILGLTSITYGEVDVFGENIKGREKQVYPRIGAIIETPGFYPNLTGTENLEIF
                     AKLRGTAAPNSVKRALEIVGLPYKNKKLFSKYSLGMKQRLGIANAILHDPELLVLDEP
                     TNGLDPIGIAEMRKFIRDLSVEHGKTILISSHILSEISLLADDIGIIDHGVLLEESSM
                     SELEKKNSKYILLQVSDIPKTSLILERQFNTKDYSVQDDYTLHLYNTNLDMGEINKAL
                     VMQNVTVISSQLCNDTLEDYFKKITGGEGIA"
     gene            18809..19546
                     /locus_tag="KR231_002835"
     CDS             18809..19546
                     /locus_tag="KR231_002835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBH0005197.1"
                     /translation="MLKLIQTEFLKLRRRKLIWLMLLSALIMPFFALLYFNYFGKTGV
                     EPIKFYKWSAFGYTLWIILPVVLGIFCTMLIHEENQYDMLKQLWIVPISKMGYFFSKF
                     FVVLIYSICFMLITAVASVLFSVLSGYVVFSWASILYLLKKCLEIGVITAFVMLPILA
                     IATSQKGYILPICITLVYAFSGFVIMTINMYLHPLSSMGVIIMRNKDIPGLIFSQEIN
                     VPLAFLCICIWSIVSVLFANIALGRRK"
     gene            19557..20330
                     /locus_tag="KR231_002836"
     CDS             19557..20330
                     /locus_tag="KR231_002836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBH0005198.1"
                     /translation="MWKLLWAECQKIRRSKIVWITVFASIMIAVIVFAGGQDVYNDPD
                     LHYGLKSVYDGSRYIDNAGWYMDAVQPWSTFFVLPAVIALLGSYIICREEEEDTIKSL
                     RLIPINETNLTIAKMIITFIFSILLYLLLFTITFLTESVLHFSDLSTKLVLSCMKEYF
                     LDGIGVFFAISPIIALVSRMKKGYWLALVFTEVYSIAGLFAGMSNVLQTFFPIAAIFN
                     ISGYYITTGEKIMGSIMSLLLCACLSAFILKGLKHNEKN"
     gene            complement(20871..21479)
                     /locus_tag="KR231_002837"
     CDS             complement(20871..21479)
                     /locus_tag="KR231_002837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DedA family protein"
                     /protein_id="HBH0005199.1"
                     /translation="MSVINSFILQYGLISVFVLIMIEYACFPLPSEVVLPLCGAIAAR
                     NHFGFLTILILSIIAGILGSIFCYTVGNWGGKSIINKIIEICPKAKKGIFASQDYFNK
                     YSSISVCVCRLIPLCRTYISFIAGIAGQNIITFVISSIVGITIWNTSLISIGYIFSES
                     WVRIMSHYNDYKFLVLIIPISIIFIGFVIKSFIHKKHHKIRL"
     gene            complement(21657..21773)
                     /gene="rrf"
                     /locus_tag="KR231_002838"
     rRNA            complement(21657..21773)
                     /gene="rrf"
                     /locus_tag="KR231_002838"
                     /product="5S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00001"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00001"
BASE COUNT         6934 a         3791 c         2866 g         8231 t
ORIGIN      
        1 attaaatttg tagtatttat gtaagaaata aattttatat aatatttttt cactaaattt
       61 ttttcttttt acaacaaata ctcactacct tttgatataa tatttttatc aattattatt
      121 atattcaagt tttgaaagga gtattaaaat gagtttatta gttttcggac ataaaaatcc
      181 agatacagat tcaatatgtt ctgcaatttc attagcacat ttaaagaaca aactaggaat
      241 aaaagcaaca gcttatgctt taggagatat cagaaaagaa gctaaatatg ccttggatta
      301 ctttaaggta gatgcacctg aaattttaga taatgttaga atacaagtta gagatttaaa
      361 ttatgataaa gtagtacctt taacaccaac ttcatctata ttagaggctt ataaccttat
      421 ggatgaaaaa aatgttaaaa cactacctgt aacttatgat gatggaactt ttgctggtat
      481 cattactatg aaagaaatag ctaaaaatct acttcatcaa cactttacaa ctatacacac
      541 atcactatca aacatttgta aaaaccttaa tggtactatt cttgtggact gtggtgaaga
      601 tataaaaggt agagtagtca ctttatcatt tggaatggag actctaatag agactttaaa
      661 agaaggagac atagctattg ttggagatag atatgatagt attgaatatg ctattgatac
      721 aaaagttaaa cttttaatac ttactaatca tacagagatt tcaaaagatt tgctagctct
      781 tgctaagata aatggagtgt ctgttgtttc tgttgaaagt gacaattata aaacttctaa
      841 tgtaataaat caatgtagtt tcttagactc tatagaagct acagaaaatt taattacatt
      901 caaagaagat gattatatgg atgaaataaa agagattatg ctagaaacaa acttcagatc
      961 ttatccaata ttagatgatg ataataagtt tttaggttta gtttcaaaag gtcatctatt
     1021 aaacccatct aaaaagaatg ttgttttagt tgaccataac gaatatgctc aaagtgctga
     1081 tggaattgaa caagcaaaca tagttgaaat aattgaccat cataaacttg gcggtatttc
     1141 tactgatgtt cctatgtcat ttagagttat gcctgttgga tgcaatagta ctataattta
     1201 tcaaatgtac aaagaaaata atgttgagat accttatgaa atagctgggc ttcttttatc
     1261 tgctatatta tcagatacat tattatttaa gtctccaaca acaactgata tggataagaa
     1321 agcttgtgaa gaattaagta aaatagcaaa agtagacatg gaaaaatacg ctatggatat
     1381 gtttaaatgc ggtacttctt tagatgaata tactatagaa gaaatagtaa atatggactt
     1441 taaagaattt aatatgagtg gacatagagt tggtattgga caagtattta ccttagacat
     1501 agactctata tttgctaaaa aagatgagtt tttatcttat ataaattcga ctgattatga
     1561 taaattaatt ctttcagtta cagatataat caaagaaggt tcttatttaa tctataaagc
     1621 agaagatagc ttaattgcta acgcatttgg tgttgaaggt gttcaaggca catttgcacc
     1681 aggtgttgta tcaagaaaaa aacaattagt ccctaattta actactgcaa tcaaaaattt
     1741 taaataatat aaaattttta aataacgaaa actgtctcaa atctatattt gagacagttt
     1801 tttattatat atatattgat aataaagtta aataaaaatc cataaattta aaatttttat
     1861 gaatatattt tattattatt gttattttat tcattctaaa ataggtaaaa ctcaatatat
     1921 aaaaatactt ttgtcattta aataaaacct aaatagtttt taagattatt ttagacacgt
     1981 tttaagtcat aacagtatca gctattctaa atatcgtcaa agtagccgca gttcctgctg
     2041 attgcccatt tcgtatccct actgttgtag atgaaaagtt atttattgta aaagtagtcc
     2101 caccaaataa aaaaccagca aaatatccag aaagtactcc tccgcctcct ggctcagtag
     2161 taagccctgc caaatctttt cctcctaaaa ttgggaatag gatagcgaaa gaatattgat
     2221 ttatacttga tgaacctggt tgtaatgcta ctgaaactga tatataatac acaccatttt
     2281 cttgtactgt aaacgtacca tttgcatcta ctgttatact tgaactattt cctattattg
     2341 tttgccaacc tgttatagca tctccattat ttagtgtttg tggagatggt gcatttacga
     2401 ggaagttagc aactggctga gaggaattgc ctgttgctcc tgttggacct gttgggcctg
     2461 ttactcctgt cgctcctgtt gctcctgttg gacctgttac tcccgttggc cctatacttc
     2521 ctgtcgctcc tgtatttcct gttgggcctg ttggtcctgt tgctcccgtt ggtcctattt
     2581 ctcctgttac tcctgttggg cctgttgctc ccgttggtcc tatttctcct gtcactcctg
     2641 ttgggcctgt tgctcccgtt gggcctgtta ctcctgtcac tcctgtattt cctgtcggtc
     2701 ctgttgctcc cgttggtcct atacttcctg tcactcctgt tgggcctgtt ggtcctattt
     2761 ctcctgtcac tcctgtcgct cctgttggtc ctatacttcc tgtcactcct gttggtcctg
     2821 ttgctcctgt tggtcctatt tctcctgttg ggcctgttac tcctgttggc cctatttctc
     2881 ctgtcactcc tgtcgctcct gttgggcctg ttgctcccgt tggtcctatt tctcctgttg
     2941 ggcctgttgc tcctgttggc cctatttctc ctgtcactcc tgtcgctcct gttggacctg
     3001 ttgctcctgt tactcctgtt actcctgtat ttcctgttgg acctgttgct cctgttactc
     3061 ctgtatttcc tgttggacct gttgctcccg ttggtcctat ttctcctgtc actcctgtcg
     3121 ctcctgttgg acctgttgct cctgttggtc ctatacttcc tgtcactcct gttgggcctg
     3181 ttactcccgt tgggcctatt tctcctgtca ctcctgttgg gcctgttgct cccgttgggc
     3241 ctatacttcc tgtcactccc gtatttcctg tcggacctgt tactcctgtt ggtcctatac
     3301 ttcctgtcgc tcctgtactt ccggttgggc ctgttactcc cgttggccct atacttcctg
     3361 ttgctcctgt atttccggtt gggcctgttg gtcctatgct tcctgtcgct cctgtacttc
     3421 cggttgggcc tgttactcct gttgggcctg tacttcctgt cgctcctctt ggtcccattg
     3481 gacctgtaat tctaattgga agacactcac atttaggata acaattatct ataattctat
     3541 cttcaaatgt tacaagtata tacggtttgt tacaacctct actagatgta aattcaagaa
     3601 tctgataagg gtaatttaaa gataaagcta acccataatt aggatattta ttcattgccc
     3661 atgcttttat agttcccgta atatttaaac aaatatagtt ggatgtatca cttatcccaa
     3721 ttggtaaata tcccctgata ttttccatag acactctatc attccatgtt atagttcgta
     3781 aattataata ttcacttatt cttttaattt caatatctac tttttcttta aaaatatgat
     3841 tcttatttga atcaatatga ataaataact ctgcttttaa tatacttttg tcttttaata
     3901 tatctggtat tctcacttta aaaaaagtaa tcaacttttc ttttacaaaa ctatttgaac
     3961 atttacttcc tattaagcaa taatctaaat tactaaagtt tttatctgga tattttttag
     4021 atataaaagt atcatcattt aaataaagta taatatttct catttataat ccctccattt
     4081 tgggtctata tcatactatg tttaaaatac atgcttagtt acaatacaat taaaatttat
     4141 agtattaaat ttttatataa taatgctgat ttctacaaaa aaagaacatg tcattagaaa
     4201 tttctaatag catgttcttt ttcattatta tatattacac tttaaattat tccttgactg
     4261 gcttagctgg tgtaaactaa accagtcttt ctaaaatatt aagcactttt ttcttattat
     4321 gttttttagg atttattgtc tatattattg taaaccaaag ttataaaatt gtaaatagaa
     4381 tatattacca taacaatatt tttttataag taaaaattat aaaaaacttt atttttgtta
     4441 aatggaataa ataaaataag tttaaaaaat actgaaataa gtgttttcca catattttat
     4501 atatttattt aatacattat tatttaaaaa taaatatata aacaatcata ataaaatttt
     4561 tttaataaaa ctttattttt tagttaaaat catacaatat atagatttcc acaatacaaa
     4621 taaattaaaa agtgaaatgt atttgtctaa aaacataata acatttcact ttatcctcat
     4681 ttttaagtaa tatatatttt taatttttat ttataactaa atctagtttt tatataaatt
     4741 ttagtttttt tctacatctg agtaatctat tccaaaagtt tctacagtaa cagatttcat
     4801 aatttgtgga gtttgtggct tatcagctga atctgttcta actgatgcta tttcatcaac
     4861 tgtatccata ccttctatca ctctaccaaa acctgcatac tgaccatcta agtgtggtga
     4921 gtttttatgc attatgaaaa attgagaacc agctgaatta ggtgccatag ttctagccat
     4981 tgatatgact cctctttcat gttttaaatt gttagtaaat ccattaccac taaattcacc
     5041 ttttattgag tgacctggac cacccattcc tgtaccattt gggcatcctc cttgtatcat
     5101 aaatcctggt attactctat gaaatattat tccattgtaa tatccttcat ttactaatga
     5161 tacaaagttt ttaactgtat ttggagctat atttggatat aactcaattt tgatttcttt
     5221 tccattttcc atttctatag ttactatagg atttttattt tccataattt attaccttcc
     5281 ttttcattag ttaaattaca taattacatt tattatatta tactctaaat taaagtctat
     5341 caagtatatt ttttcctatt tcatatcctt cttgataaat agttttacaa aactcatcat
     5401 caaagttaag cgtgtcttta ggagcaaatt gagtattagg tctaactact attattttat
     5461 cttcatcata tactttttta atatcttctg gcaactcata attatatttt gtggatatta
     5521 aaataatttt atccacatta tccccaatta atggttcaat taatgcactc ctaattaaac
     5581 ctccatctaa tttgaaacca tcataaattc cttcttgcac atctttcaca aattgttctt
     5641 taaatccaag agttgcgttt ggatttgatg gtaacaaccc actgtatgaa atgctgataa
     5701 tggcttcatt acgaggcatt tttgatacat caacaatctt ttctgatact actttattat
     5761 caacttcaac ataattaaca taaaagttca tttcttctat attactatca tctagttccc
     5821 ttaggttgtc tatagcagga gaattatcca cagtattatt tactattttt acatttccat
     5881 tctggatatc ttttatattt gtccacattt tctccaagtt atcaacattc cctgtgtaca
     5941 aataatatcc atttattgct cctattgatg tccctgaaat cgaataaaat ttatttattc
     6001 ctccatcata caaggcttta actactcctg cttgataagc cccttttgct cctccacctt
     6061 ctaaacataa tcctaatttc atagtctcat ctccaaattg tttatcttat atttatattt
     6121 caaaaaactt actaaatgtt ttatatatac tatagtggtc ctcaacattt cctaattctc
     6181 ttatagaatg cattgctaaa attggacttc ccacatccac agatggtata tctatatgag
     6241 tagaagatat tggacctata gtacttcctc ctctttcatc tgacctatta acaaattctt
     6301 gatactcaac attagcttct ctacatatat ttttataaat agctatagaa tatccatcac
     6361 tagtatacgc ctgactagca tttatcttta taaccggacc ttttcccatt attggtttat
     6421 tagttgggtc atgcttttct ggaatgtttg gatgaatagc atgagctaaa tctgatgata
     6481 tcataaaaga tgaataaata gactcaaaga atccctctct atccttaccc attgatatac
     6541 aaattctctc caatatattt aacaacatgt ttgaatctgc accttgttta gtagagctac
     6601 caacttcttc attgtcaaat acagccatta catttacacc atgttgacct ttagtattaa
     6661 caagagcatt caaactagca tgtaccattg caagattatc ttgtctccca atagatataa
     6721 attcatcatt agcccctatt aaacttcctt tttcaaattc atataaaaat aaatcaaaat
     6781 ctataatatc gtccatattt acatctaagt tagatgctat ttgctttata agaaaattat
     6841 ctttttctaa tgtatcattt aacatcccaa ctaaaggtaa catatctttt tgcttattat
     6901 atgaatgacc atcatttata cttctattta aatgtattgc tagatttggt attatacaaa
     6961 ttggcttttt aaagtctata agcctttcat ttggttttaa tatactatca ccttttaaaa
     7021 ctactctacc agctatccca agaggtctat ccaaccatgt acttaatatt gctcctccat
     7081 agcattctgt atttaacttc aaataagatt tttcagcttc tatttctgca tttggtttaa
     7141 tactaaatgt aggagaatct gaatgagagc ctattattct aaatccatct ctttctatat
     7201 cttctgaatt tactacaaaa gctactatag ctgataaatt cttagtaaca taatactttc
     7261 caccaactct tagattccat ctttgattca aaactaattc ttcaaatcca tttttatcta
     7321 agatttcctt agtactcttg actgcatgaa aagacgacgg actatcatat atgaagtcta
     7381 ttaagttttt agcaaagttt atactatcca ttcctcattt acctccatta taaaatattt
     7441 agtgttgtat attctttatt tattttttta attccctgtt ggtcaaaagc tatagtaaca
     7501 tctgtaccaa ttatagaaac cactgtccca accccaaatt taggatgatg taccttagaa
     7561 ccaagtttta tatcatctgg attagtttct ttattagaat cttttattgt agcattaact
     7621 ttatctgcaa ctttagattt gcttatagta ctcatatact ttttagtata tttatctaac
     7681 atattataac ttgctttaga atagcttagt tcttttttta ctttgtacaa tctttctata
     7741 cattcttctg gcagttcttc cataaatctt gaagctattg caacatttgt tttaccatat
     7801 aatgttctct tctctgtcaa tgacatatat agctcttctt tagctctagt tataccaaca
     7861 taacaaagtc ttctctcttc ttctatttgt gaatcactca tagattttat agctcttgat
     7921 ataggaaata acccttcttc catacctgtt aaaaacacaa cagggaactc taaaccttta
     7981 gatgtatgaa ttgtcataag cgaaacccta tcattgtctt cttcatcatt tgattcagat
     8041 gtaagtgcta tacttgttag gaatgtctct aagtctttat tttcataagt atcatcatta
     8101 ctactttcaa actccaaagc tatagaaata aattctctca aattatcaat tctgtcttga
     8161 gcttcttcac ctttgcctgt taaatctttt tcatttttat ttcttatctc tacaagctcg
     8221 tccatatatc ctgtagtgtc caagactttt tctataagtt tgctaacagg ataaacttct
     8281 tttatagttc taagagtccc tataatatca acaaatccac ttatacttgc ccttgcctta
     8341 gtagatatat ctgaatttgt ttctatatca attaatactg agtatatact ttcctgtttt
     8401 aagttagctc tatcttcaat tttttctatg gttctaagcc ctatacctct tctaggaaca
     8461 tttataatcc tttttataga tatatcatct tgtggatttt gaataactct taaatacgcc
     8521 aacaaatcct ttatttcttt tctctcatag aattttgtac caccatatat attgtatgga
     8581 atttgacttc tatttaaagc gtcctctaca ggtcttgcct gtgcatttgc tctataaagt
     8641 actgcaaaat ccttataagg tctattttct tttctagcta tttgtgcaat tgaatcagca
     8701 atgaaatcag cctcttctat ttcactacca gttaattgta tctttataag ttctccttct
     8761 tttttttcac tccaaagctt ttttcttttt ctttctatat tattagatat aactttatta
     8821 gctgcatcta atatcacttg tgtagaccta taattttgtt ccaactttac aacatgtaca
     8881 ttgtcataat ctttctcaaa ttcaagtatg tttcttatat ctgcacctct ccatccataa
     8941 atactttggt catcatctcc aacaacacaa atattttgat gttctcttgc taataatttt
     9001 atcaattcat attgagcttt acttgtatct tggtactcat ctaccattat gtatctaaat
     9061 ctacttctgt aatatgctaa cacttcatca ttagccttga aaagttctac agttttaagt
     9121 attaaatcat caaagtcaag tgcactattt ctttttaaac ggtcttgata tagcgcataa
     9181 atatctgcaa tcttaaccat tctattatct gccatattga tatctttaaa ctgctttgga
     9241 gtataaagtt tatcttttgc tcctgaaatt gcacttataa ctgcttttgg ttcaaacact
     9301 ttatcactta aatttaattc ttttagacag tctttaacca atgtaacttg gtctgctgaa
     9361 tcataaatta caaaacttct attgtaacca atcttattta tatcttttct tagtatacga
     9421 acacagcaag aatggaatgt acttatccac atatccttag tttcaggacc tatattttgt
     9481 tcaactctct ctctcatttc atttgcagct ttgtttgtaa atgttatagc taatatattt
     9541 ggtgcttgta cacctttatc ttctataaga tatgctattc ttgttgttaa taccttagtt
     9601 ttacctgaac cagcaccagc cagtataagt actggacctt cagtcttttc tactgcttct
     9661 ctttgagcag gatttaatgt atctaaattc atatttctcc tcctgttaac agccataaat
     9721 atattttaat ctaaaatatg aattacttca aattataatt atgtattata ttaatagatt
     9781 atttccaata tattacaatt aaataacatt tttccatata atttatttca ttgtttaata
     9841 aaaaaaataa ccttatgatt tggggaatca taaggcacct ttaaggggtc taggttaagg
     9901 gttattatat ataaatctat ttttttaaaa taggtttagg gcttaattat ttatttgtat
     9961 taagttctct ttccttccaa tacttataca aatcttcttc tttcttaaat aagggtaaat
    10021 tcatatttct atgtactttt actaaccatg gggattctag gccagcttgt ataatattat
    10081 tttcatttat aaacacattt tctgcttttc cttcatcaat caaaatcccc ttatccaata
    10141 catatatgta atcacatatt tcatacatta aattcatatc atgactggat attactattt
    10201 ttatattatt tttatttaat ccctttatta tatctacaat agacctagta cttactgggt
    10261 ctaaaccagc tgtaggttca tcaagtaata caatttcatt ttccattgct ataactgatg
    10321 ctattgccac tctttttttc tgtccatagc taagaaaatg tactggcctg tctataaaat
    10381 ctattccatt aacagctact agagctttgt ttattctctc tttaattgtt ttttcatcca
    10441 taccaatgtt tctcattgca aaggctatat catcatatac ttttgaataa aaaatttgtt
    10501 tttctgggtc ttggaacaca atacctacat tttttctaag gttgtataaa cttctcttat
    10561 catattttaa cttttcttct ttaaaaagaa tttctccaga tgtaggcttt aatataccca
    10621 ttaaattcat aaataatgtt gattttcctg aaccatttga acctattata cctataacat
    10681 ttccctttga aaaatccata ttaatgttta atagtgcatt ggtatttttt tcatattgat
    10741 acgttaaatt atttatttta aacatcatta tcccctacta tgtgaaattt accatcatac
    10801 aattttatgt ctaatgatat acacatatca tcataccttg tcataagtct tttgtacagc
    10861 atacttccaa gaatacctaa ggatttatat gaagttttta aatttatata tccaaatctt
    10921 agctcttgtg acttgtatat ttctgaaaat tcttctaaaa atatgaatat aaacctatat
    10981 attaacattg ataactcgac aaaagtgtca ggtaaatgaa gttttttaaa aaagaatatt
    11041 aattgattaa aaggtgttgt aagtatacaa aaatacacac aagtcaaaca agacatcgct
    11101 ctaaataaca catgaataga catgtcaata gacgcctttg atattcctac attaaaacta
    11161 aaaaattcaa aactatataa taaatctgct ttattaaaag atatatttac aagagttatt
    11221 cctatactaa gaaataaaaa gtacattggt attctaagta attttaaata attttttaaa
    11281 tctattccag ccacacaaac aaccaaaata ctcattaaaa tcataattcc acttaaaata
    11341 aatatatttt gtattaccat agaagcaatc agaaaaatta ctcctatggc tacttttttg
    11401 tttggattta ctttactcaa tctatttgta tatgcatatt tatcaattat aagcatgatt
    11461 aacttctctt tcctttttga agacctaata tgtatcctat tacaccagcc cctaaagctg
    11521 cttgtgcaga gaataataaa ctttctattt ctccacttgg tggctcatat ggactgctaa
    11581 accatggttt gtaatttgga tttatcttag taatttcact ttcagcttga ccatctgctc
    11641 ctccatattc agcacctgag ttgacaagta atgggaatat aataagagct actactaata
    11701 aaagtaataa tatgttagtt tttgttttag cactcattag ctttaactcc tttatcatta
    11761 ttttctagta tgcttttttc tccgttttct gtaattaaat tatatacaat tacagtaagt
    11821 ataccttctg ctattgctat tggtatttga gtcataaaga aaattcctaa aaatttaatt
    11881 gctgaagcca ttaccccacc tgatgggtct gggaaagcca gtgctaattg tattgaagtt
    11941 attgtatatg tggctaagtc tcctattgct gctgcaagaa atactggaat agcattattt
    12001 ccatcttttt tctttaaagc cttaaatatt aggaatgata cgattggccc tattatcgcc
    12061 attgaaaaag cattagctcc taaagtagtt attcctccat gtgctaataa caatgcttgg
    12121 aatattaaaa ctatagttcc aagaacaaac attacgcttg gtccaaacat tattgctcca
    12181 agacctacac cagtaggatg tgaacaactt cctgttactg aaggtatttt tagtgctgat
    12241 aatacaaaca caaatgctcc acataaagct aataatactt tctttttagg gtcttgcttt
    12301 actattttac ctattgattt taatccgaat aagaaaaatg gtataaatat aactccccat
    12361 gctatagacc attttactgg taagtaacct tccattatat gcattgcatt tgatgtaact
    12421 ggagttaaaa tgattaacat aagtgcagct ataaccccta atttaatatt ctgtttcatc
    12481 ttagtatccc tctctccctt tctaataatt aaaacataat aatacatgtc tgatttattt
    12541 aataaaataa aaaagcctaa ctcgatggtt aggcttctaa ttttccacaa tctaaataca
    12601 aacacataaa acaaacatat ctgtataatt attataagaa actttctcca tccccgaaga
    12661 aattacttta atattttagg caggtctcct gacttagctt catcctactc ctcttccttc
    12721 ccatgagata taaaaaatat catcatagtg gctaacaaaa gtttcgtctg catcacagta
    12781 gcgggggctg taaaggaatt taaccttttt ccctattaat cttgcttaaa gaacctataa
    12841 tattatatat ttaattttta aattcttctt aaattatttt ctatataaat cattgtatac
    12901 cttttctgtg aaaatttcta cattttttat aaattttatt catttttata tttttatgta
    12961 tataaattct tttttgtaag tttattaatt tctaattatc ttctttaaat acattgaaac
    13021 tacatcagaa aatctagtta tatctcttga atatataaaa tcatttccat atattaatct
    13081 ttcagcttca agttctgatt cttttcctgt aaatactcct aatactaata tattttgctt
    13141 tctagctttt ctcacttcat tggctgtatc tctcaaacca actatacccc tataagcctt
    13201 ttctcctctt aatgttctct cactactttt tcctatcttt acatcatttg gtcttccatc
    13261 actgagaact atcaggattt tattttcttc atctctattt attagaccac tacatataga
    13321 ttttattgcc aaaccatctc tattattacc agcacaaaaa tattcaaata tattttcact
    13381 attttttata ctatcatcat aatctttaaa tctttttaat attgtatagt ctaaaaaact
    13441 agaaaatccc atcactctat ttggtatgcc aacttctgtt agagcatttg caattatgta
    13501 agcttgaatt gccacatttc cctgatttct actttgagag ccacttgcat ccaataatat
    13561 atcaataacg tatttccctt tttcattttc tatatcttta taaaatattt tattattatt
    13621 acttctacca actctccaag ctctattggc taatatagta ccacaatcag aatatactct
    13681 acttttagca ttttcttcta ttaaaattct tgatagactt tcttttaatc tctttatttg
    13741 ctgtctatac attctagcat gttctctaaa ttttcctaaa ttattttctt tttgtcttgt
    13801 tacatatttt agttgaaata cattattaca ctcacttcta agaactccat ctgtaaagtg
    13861 tattctacaa ccttcatgaa catttctaca attttgtgtc tcaatttttt taatttcacc
    13921 tttactcaaa taagtttttc cataataatg ttctattttt gaatatatct tatttgcagt
    13981 gtcttcatca acatatataa ctcggtctgc tgaattgcta catttagaat catcaaaatc
    14041 ccctacacct tctacaagca tggatgaaga tattgaatct atatcacttt caataatatt
    14101 ttcttcttca tcactataaa gttcttcata catgaaatca gcaaatgtat caaaatttac
    14161 ttctacactt tctacattat tttcatcaat aagactattt tcttctccat ttaatatgta
    14221 ttcaaaataa gttaaatata taacatctaa tgcttttaaa atctccataa tatcttgatt
    14281 ggtatctata tttcttatat cattaactat tcttctagtc atactatcta atgctgggtg
    14341 cttgtccata ctataaagta caaatgtgta tttaatttta tccataatat tatcattgtg
    14401 tattttggta aaacgtgaaa caatatcttt ataagcattt cttcttatgt cttctatccc
    14461 tggcctatct ttaatgacct tttcttcaac tattgtattt aatataactt gaattagacc
    14521 cagtataata tctttgttgt atccttttct tattctattt gtaagatatt ttttaactat
    14581 atcccaatct acatactttc ttctagcacc tgcaattatt gcaaaatata gacctatttc
    14641 ttttgaagag taatcttttt ctgatatatc tatactttca ttgtaatcac cagctattgt
    14701 ccatgataag ttattagctc tattttcaaa ttcataatca tcatatatcc atttcataat
    14761 ctcacctata ttaaatatga cttattggaa acacatctat actctcccat ttattaggta
    14821 ttctagtttt aattacatct ccaaccattt ctttctcata tacatcaaaa gtctttcctg
    14881 taagtcccat attaattgca agagttggtt ttaatcctct tcttatagtc ttaagagatg
    14941 ccataagacc acgtaaatca atagctttac tagatatctc tccattttga gacttcaatt
    15001 gtaaatctaa aaatattcct gcaaagtgta ttagtttttc ttcatcagca tctgaaaatt
    15061 cattttttaa aatcatcatt aacttatctt cttctatagg aggaatatct attaccataa
    15121 atctagatac cagtgcttca ttaagttctt ttgttcctgc atattcataa ttcatagtcc
    15181 caataaatct tgttgctgga tgtagattga ctctctcata cccaggtaca tcaattattc
    15241 ttctatagtc taaagctgaa tgtaccacaa ctatagcatc attttttgcc atattaattt
    15301 catcaaacac cccaaaacct ccattaatag cacactcata aactgagcct cttctaagtt
    15361 taacttcatt gtctataaat gtatctgtac ctataagtgt tgaactgtct gtatttatat
    15421 gaaatgatgt attccactga ggtctattaa atatttcccc tagattatca gcaagtaagt
    15481 tttttcccgt tgcctttggt cccgataata atatattttc ttcttctaaa atagctgcta
    15541 tacacataga caagatatct ttaccataaa aataagtttt agactttgtt actctgtatt
    15601 ctaaatcttt ttctaatcca taataatttc taaaatacag tacatcttca ataagttttt
    15661 catctacccc ttgcaccctt agattatcta ttatatccat atttttaccc cttttatata
    15721 aatagtattt gtttcatttc ttatcaccat tttagcataa aaggatataa gctaaaattg
    15781 attttttaat ctcccccatt ttaagtaaaa ccatgcacca ttttatcact acaaaattaa
    15841 gagtactact tactgatatt tcttgatttt attcgtctat acgtatataa tatatactga
    15901 taaattatga ggaaaggatg attgaaatat ggaatatatg tcttgcccag aagtagcaaa
    15961 aaaatggggt atttctgaaa gaagagtaca aaaactatgt gaagaaagtc gcataccagg
    16021 agtttcaaaa ctcgggtata tgtggctgat accaaagaac gcagaaaagc ctgttgatgg
    16081 tagaacaaaa agaagaaagg aagtacaata tgaatagcgt tttgattata gatgatgaca
    16141 aagaactttg tgctcttatg aaaaaatgtg ttgagcaaga aaatttatct gctattactg
    16201 cacatggtgg tgcagaaggt ctacatttag tcgataaaaa tagacacaca ctctctcttg
    16261 taattttgga cataatgatg ccagatatag acggttttca agttctgaaa aaaattagag
    16321 aaacaagtaa tattccagta attatgctta ctgctaaaaa tgacgaggat gataaagttt
    16381 ccggactacg tttaggtgct gacgattacc taacaaaacc gttcagcata aacgaactta
    16441 tggctcgtgt caattctctt attcgtcggt atactatgct aaaccctgct tttataacag
    16501 acacagattt cataataata aatggcatga ttattgacaa gacaaaccga attgtttctg
    16561 tcaataatat tcctgttcaa cttacaagca aagaatttga tttacttgct tttctggctt
    16621 ctaataaggg acgggtgttt accaaaaaac agatttatac acaagtatgg gaagaagaat
    16681 atgcttttga cgatagtaac atcatgtctt tcatcagtaa attgagaaaa aagattgaac
    16741 cagaccccaa ccatccattt tatattttga cagttcgtgg tgtcggttat cgttttaata
    16801 aggaggctta acatgaatac aagtgtctat ctgcttttga tattggctct tagcctgatt
    16861 attatagcgt accttgtttc tgtcctgcta cgtgtccgaa tacaacttac acttataaaa
    16921 gatgctttag aggatataaa aaatggaaac cttaatcgac gtattttaac agatgaaaac
    16981 gacattacaa aacaaatttg ctatgatatt aacgaaatag caatcaatag ccaatttcaa
    17041 cttattcagc aaaaacaatc agaacaagcc tacaaacagc taatgacaag tctctcccat
    17101 gatgtaaaaa ctccacttgc ttctttggtc ggttatttgg aagcagtaga aagtaaaatt
    17161 gttgtaggag aggaaaaaga cgagtatatc catgttgcgt ctaataaggc tcattactta
    17221 aagaattttg tagaaaatct atttgaatgg gtaaaattgg attctaagga acaagttttt
    17281 cattttgata tttttgactt gaatgaatta tcccgtaata ttatatctga ttggatacct
    17341 gttttagaaa gcagtcattt tgaatatgaa tttgatatac cagaaataga gtacttctta
    17401 cgtatagacg caaatgcata tacccgtatc attaataacc tattacaaaa tattattacc
    17461 catagtagtg gaaacaaaat gacattgaga atttttgaaa acaaagagca agctcaaatt
    17521 ataataacag ataatgggaa aggtatatct tcagacaatc tcccacatat ttttgaaagg
    17581 ttgtaccaat gcgaccattc acgagcttca aagggaaatg gtttaggctt ggcgattgca
    17641 aaggaactta ttaacgctca taagggaaat attaccgcca acagcactcc cggtatggga
    17701 acagaattta caatattgct tcctaaagcc ctgtaaaagt acgaggcttt cttactctaa
    17761 aacaagataa aagcaagatt atggcaaggt tttggcaagg ttcatgtttt ataattctaa
    17821 ttgtagttga ttttgacgtt gtatcaacta tcttttgtag aaacaaattt attaaaagtg
    17881 aggaaattat atatgaatga ttttgtgatt gaaacaaagc aacttacaaa aatttatggg
    17941 aatcaaacag tagttgacaa agtcaatctc catgtaaaaa aaggccgaat atatggtctg
    18001 ttaggacgca acggagctgg gaaaaccaca attatgaaaa tgattttagg attgacttca
    18061 atcacgtatg gcgaggtaga tgtatttgga gagaatatta agggacgtga aaaacaagta
    18121 tatccccgta tcggtgcaat tatcgaaacg ccaggatttt atcctaatct gacaggaacg
    18181 gagaacttgg agatttttgc aaaactgcgt ggtacagccg cccctaattc tgtaaaaaga
    18241 gcattggaaa ttgtaggctt accttataaa aataaaaagc tgtttagtaa atattcactt
    18301 ggcatgaaac agcgacttgg tattgccaac gctatcctgc atgacccaga actgttagtt
    18361 ttagatgagc caaccaatgg tcttgaccct attggtattg cggagatgag aaagtttatt
    18421 agggacttga gcgttgagca tggaaagaca attcttattt ccagtcatat tctttcagaa
    18481 atctcattgt tggctgatga tattggaatt atcgaccacg gtgttctttt ggaagaaagt
    18541 agtatgagtg aactagaaaa gaaaaacagt aaatatatcc tgctacaagt ttcagatatt
    18601 ccgaagacat cacttatttt agagcgtcaa tttaacacga aggattattc cgttcaagat
    18661 gactacacgt tacaccttta taacactaat ctggatatgg gtgaaatcaa taaagcactt
    18721 gtaatgcaga atgtaactgt tattagttct caactttgta atgatacttt agaggactac
    18781 tttaaaaaaa tcacaggagg agagggcatt gcttaaactt attcaaacag aatttcttaa
    18841 actgcgtcgt aggaaactta tttggctgat gttgttgtct gctctcatta tgccgttttt
    18901 cgcactacta tacttcaatt attttggtaa aacaggtgtt gagccaataa agttttataa
    18961 atggtctgca tttggttata cactttggat tattttgcct gttgttttgg gtatattttg
    19021 caccatgctt atacacgaag aaaaccagta tgatatgctc aaacagcttt ggattgtacc
    19081 tattagtaaa atgggatact tttttagtaa atttttcgtt gttttgattt actctatttg
    19141 ttttatgctg attacagccg ttgcttctgt gttatttagt gtactttctg gatatgtcgt
    19201 atttagctgg gcaagcattt tatatttgtt gaaaaaatgt ttagaaattg gtgtaatcac
    19261 tgcttttgta atgttgccga ttttggcaat cgctacatct caaaaaggat acattctccc
    19321 aatttgtatc acattggtat atgccttttc cggttttgtt ataatgacaa taaatatgta
    19381 tttacaccca ttatccagta tgggagttat tatcatgaga aataaagaca ttccaggtct
    19441 tatattttca caggaaatta atgtcccatt agcatttctt tgtatttgta tttggagtat
    19501 tgtatcagta ttgtttgcaa atattgcact aggaagaaga aagtgaggtg tagataatgt
    19561 ggaaattact ttgggctgaa tgtcaaaaaa ttcgtcgttc aaaaattgtt tggattacag
    19621 tttttgcatc cattatgata gcagtcatag tttttgcagg ggggcaggat gtatataatg
    19681 acccagattt acattatggc ttaaagagcg tttatgacgg ttcacggtat atagacaatg
    19741 caggttggta tatggacgca gtacaacctt ggtcaacttt ttttgttctt cctgctgtca
    19801 ttgccctatt aggaagctat attatttgtc gtgaagaaga ggaggacact attaaatccc
    19861 tgcgtcttat tcccataaat gaaacaaatt taaccatagc aaaaatgatt attactttta
    19921 tattcagtat acttctttat ttgttactct ttactataac atttttgact gaatccgttt
    19981 tacatttttc cgatttatcg acaaaattgg ttttaagttg catgaaagag tattttcttg
    20041 atggcatagg tgtattcttt gcaatttctc ccattattgc cttggtatcg cgcatgaaaa
    20101 aaggatattg gcttgcatta gtattcacag aagtttattc tattgctgga ctatttgcgg
    20161 gtatgtcaaa tgtcttacaa accttttttc ctattgcggc aatatttaat atttctggat
    20221 actatataac tactggagaa aaaattatgg ggagtatcat gagtttatta ctttgtgcct
    20281 gcctttctgc atttatactt aaagggctaa aacacaatga aaaaaattga aataggtata
    20341 tcaaaatgaa aaagataaaa aaactgatta ttctaattgt attcttgttt ctttttggca
    20401 tgttacactg ttatactgaa tggaaattca acaataaccc acctaaaggg gtaatagaaa
    20461 gaataaatga gtggactgat aagattggac tggattagta acttatgtta attatagtga
    20521 atgtaatatt agcaagttat tgtttcgtat tttaatacta taactttaaa tatttggttt
    20581 taatcttcca aacgaatata aaaaaactgt cacagaggca acatattttt gaatatttat
    20641 aaagtggtag ttttgatttt caaagctacc gccttttctt ctatataagc aaacttatcc
    20701 tcaacaaagt gtaaaacatg gtgcatttta agaaaaaagt accacagaca caagcaataa
    20761 aagaaacgcc gagaacctac aaaaacgtag tgcttatgca gatttacgac gccttctatt
    20821 ttctcaaccg tcttaatgac cttgtacaaa agaaattttt ctaatatttt ttataatctt
    20881 atcttgtgat gttttttatg tataaatgac ttaataacaa atccaataaa aattatggat
    20941 attggtataa ttagaacgag gaatttataa tcattataat gtgacattat tcttacccaa
    21001 ctctcagaaa aaatatatcc tatactgatt aatgaagtat tccatatggt tattcccacg
    21061 atagatgata ttacaaaagt tataatattt tgacctgcta tacctgctat aaaagatatg
    21121 tatgttctac ataaagggat taatctacat acacaaacag aaatagaaga gtatttatta
    21181 aaataatctt gagatgcaaa tattcctttc tttgcctttg gacatatctc tattatttta
    21241 tttatgatag atttacctcc ccaatttccc actgtataac aaaatatcga accaagtata
    21301 cctgcaatta tacttaaaat taaaattgtc agaaatccaa aatgatttct tgcagcaatt
    21361 gctccacata aaggtaaaac aacttcgcta ggtaatggaa aacaagcata ctcaatcata
    21421 attaatacaa atacagagat taatccatat tgtaaaataa aactattgat tacagacact
    21481 tacttatcta tctcctttct tatttaaagg ttttaagggt acatgttcta aggattctca
    21541 ccctatattt aaagaatcaa tctctttaaa ctattatatg tatttacaca aagcatttat
    21601 aacatacttt aaaaatagta ccttaaaata agaaacttaa taaataaaaa aagattacgt
    21661 ggctacgtcc tactctccca ggcagtttcc caccaagtac catcagcgct agagagctta
    21721 acttctgtgt tcggaatggg aacaggtgta tcctctctgc tattgtaacc acataatctt
    21781 tatgcttaat atttccatta agtttttaat aagtttatag aa
//
LOCUS       DAEPHU010000069        21798 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 01A10CD0081
            SAMN05941466-rid12468953.denovo.069, whole genome shotgun sequence.
ACCESSION   DAEPHU010000069 DAEPHU010000000
VERSION     DAEPHU010000069.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941466
            Sequence Read Archive: SRR6291087
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 21798)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21798)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068158.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 22:43:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,892
            CDSs (total)                      :: 3,805
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 87
            rRNAs                             :: 8, 1, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 55
            CDSs (without protein)            :: 55
            Pseudo Genes (ambiguous residues) :: 0 of 55
            Pseudo Genes (frameshifted)       :: 21 of 55
            Pseudo Genes (incomplete)         :: 28 of 55
            Pseudo Genes (internal stop)      :: 16 of 55
            Pseudo Genes (multiple problems)  :: 8 of 55
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21798
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941466-rid12468953.denovo.069"
                     /strain="01A10CD0081"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            complement(<1..316)
                     /locus_tag="KR231_002839"
     CDS             complement(<1..316)
                     /locus_tag="KR231_002839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PAS domain-containing sensor histidine kinase"
                     /protein_id="HBH0005200.1"
                     /translation="MESKGTLSKNKVYILANGLFLVIALLNINLYTVSINMYRIILLW
                     IFGYSIVYISSFKTDEFINILKVGCLVLVFVSILGVVNLKIQKFQIVLLNLSIINMST
                     FIY"
     gene            complement(464..1255)
                     /locus_tag="KR231_002840"
     CDS             complement(464..1255)
                     /locus_tag="KR231_002840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011987989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MetQ/NlpA family ABC transporter
                     substrate-binding protein"
                     /protein_id="HBH0005201.1"
                     /translation="MKLKKLLSVALVSAIAISAVGCSNKEDKKILVGASSNPHAKILE
                     VAKPLLKEKGYDLEVKIFDDYVLPNTALDEGSLDANFFQHIPFLEETVKEKGYKLTYT
                     SKVHIEPMGFYSEKVKSLDELKDGAVIAVPNDATNGARALKLLAKNKLIEVKDGELIT
                     KKDITKNPKNIVIKEMNAEQLPTVLKDVDGAVINSNYALTANLNPTKDAIVIESSDSP
                     YVNIIACRENNKDSDKIKALSEAMNSKEVKKFIQDEYKGSIVPAF"
     gene            complement(1291..1947)
                     /locus_tag="KR231_002841"
     CDS             complement(1291..1947)
                     /locus_tag="KR231_002841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBH0005202.1"
                     /translation="MNSLIDFLTTLFPNALLQTLYMVIVPTIVATILGFILAIILVVT
                     KPDGLKPNSTINSALGFIVNIFRSFPFMILIVAMIPITRLIVGTSIGETAAIVPITIG
                     AAPFIARIIESSLNEVDKGLIEAAKSFGATKRQIVFKVMIKEAMPSIVSGITLSIISI
                     LGYTAMAGAVGAGGLGNIALIYGYQRFDTAVMVYTVIALIILVQIIQGVGNLAYKKLK
                     "
     gene            complement(1940..2905)
                     /locus_tag="KR231_002842"
     CDS             complement(1940..2905)
                     /locus_tag="KR231_002842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine ABC transporter ATP-binding protein"
                     /protein_id="HBH0005203.1"
                     /translation="MISIKNVNKYYGKIQVLKDVSIEIESGEIFGIIGHSGAGKSTLL
                     RCINGLEEYQEGSVLVSDKEVKSLNEKQMRDLRKELGMIFQHFSLLERKTVFDNVALP
                     LECFGYSKAEIKKRVLELLEVVGISEKKNDKPRNLSGGQKQRVAIARALALNPQVLLC
                     DEATSALDPNTTKSILSLLEDINKNLGITIIVVTHQMEVIKQICGRVAIMENGEVLEV
                     GDTEEIFLRNTKGLRKLIGEESIILPKGTNIKILFPKDISNEAIITTMARELNIDVSI
                     IFGKLEQFKDDILGSLIINISDKSGEQVKQYLTSKGIRWEEMINE"
     regulatory      complement(3011..3117)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00162"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="SAM riboswitch class I; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="S-adenosylmethionine"
                     /db_xref="RFAM:RF00162"
     gene            complement(3407..4351)
                     /locus_tag="KR231_002843"
     CDS             complement(3407..4351)
                     /locus_tag="KR231_002843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YafY family transcriptional regulator"
                     /protein_id="HBH0005204.1"
                     /translation="MSRAERLIELMITINAKRSFTAGELAEEFSVSKRTILRDLQVLE
                     SIGFPLYSKVGAAGGYHVLKERILPPIAFSESEVKSIFFAYQSLEYYNDLPFEQETIS
                     VLKKFLNCIPNDIQYNIENIRRKFVFWTPDRHCSTPLLKELFNIVMNESTIKIEYSSK
                     QKNSVRTIVPIGLYAMNGLWYCPAYCIKSASIKEFRVDRIVKILSIENLSSKKYKVLS
                     SIHDYLKNMEVGTDYHIKINLTDEGVKRCETEFLLARGLKILSKGGYIDMYIPKSTLN
                     WVAEYFLTFGKNATIIEPIELKHLVKSKVLELYNHHCI"
     gene            4462..4929
                     /locus_tag="KR231_002844"
     CDS             4462..4929
                     /locus_tag="KR231_002844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0005205.1"
                     /translation="MENNTIKADDIINYCLSNLDDVLLMNSWGERAIYYNPNGILKRG
                     VYVLTIKEKDSNHDKGSLVSRPNVYRVNIGLKKETFIEMFGYIPKRPGVGQIVDMDFD
                     FTKLDTIMPHPIYSWMGWICVLSPTEKTFENFKTLIGESYNFAKQKFKKRKNK"
     gene            complement(5099..5698)
                     /locus_tag="KR231_002845"
     CDS             complement(5099..5698)
                     /locus_tag="KR231_002845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0005206.1"
                     /translation="MKLKRTLFVGLALVLAIGITACTKNNEKPSENTGKNPNESVNNN
                     EGYMNYYSTSYNDYIAGLNRYSIYDTPESINNQFKDKEYPGNEKYLSDVKAAYKDSRD
                     KIQSFVTSLKKDGKTEDTELKKMNDDLIAEGERLVKDIDKRIEKLDKVSDEDMKKGQN
                     DFIKLVHGTEDVGNDIGSGFRKMIKDMNDRLGITGNNKK"
     gene            5944..6540
                     /locus_tag="KR231_002846"
     CDS             5944..6540
                     /locus_tag="KR231_002846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3793 family protein"
                     /protein_id="HBH0005207.1"
                     /translation="MSCCNSQFCCKNKIESSYIKWLLEVLGPVFLGSKPAEIINISFT
                     DVNREEKINDIYKYLYKCKKIDFIVIDKEKKGLKILFVNKKALSEKLKCKKTVNFLKF
                     LGYKQNTNVNAYLEHLVDKLKSDVFPDEIGIFLGYPLKDVIGFMGYSNYEVSMIKYWK
                     VYGDTKQSEDTYSKFLLHRKKMRKLLDYISVDKIVSCF"
     gene            complement(6638..7597)
                     /locus_tag="KR231_002847"
     CDS             complement(6638..7597)
                     /locus_tag="KR231_002847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NrtA/SsuA/CpmA family ABC transporter
                     substrate-binding protein"
                     /protein_id="HBH0005208.1"
                     /translation="MTSLIMVLVGTVGCSTTNDKKDEPAKKEASLPKEINLTYVKSPL
                     NVPSILEKKDDLFGKEFKKDNIKVNFHELTTGPEQTQALAAGELDFLHALGGTSAIIA
                     ASNGVGLKITNIYSRSPKGYMLITNNDNIKSIKDLKGKKIVGPKGTILHQLLIAALAK
                     EGYTIDDVEYVNMDIPSAASALESKSADVAMLAGPVALKTINSGAKMIVNGEGLVSGI
                     IVTAVSDDFAEKYPELVKRFMKVHEETLKYMNENKDEVMDVVSKEVGLSLDETKEMYS
                     WYDFSSKITDKDIKELEDTQEFLMSNGMQQKKINIKDMLYNQN"
     gene            complement(7631..8362)
                     /locus_tag="KR231_002848"
     CDS             complement(7631..8362)
                     /locus_tag="KR231_002848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH0005209.1"
                     /translation="MVRSGFLLENIYKKYLVDNKEHLVLDNISLNISSEEITVILGES
                     GCGKTTLLRILVGLENATSGNIYFFNNDKKCTPKVGMVFQESRLMPWLNVSENILLHT
                     EKDNRNKVDLDKYLKMMKLEKFKNSYPNELSGGMAHRVSIARALSFNPDILLMDEPFA
                     ALDYFTRRKMQKEVVNIHKNTKKGVVFVTHNIEEAMEIAKKIIVFSKNKRIKQFSVED
                     EYNRDLTKNYYINLKKEILRELGEF"
     gene            complement(8355..9125)
                     /locus_tag="KR231_002849"
     CDS             complement(8355..9125)
                     /locus_tag="KR231_002849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBH0005210.1"
                     /translation="MFEKIHKRLKGYYIFLIILILWKIVCVLGIWSSYILPPPEIVLD
                     TFIKMIYDGSIFLNVYASVRRILIGFLISSLMAIPLGVLFGVNKKMYEYFKPLFEFMR
                     STPPLALVPMLILWFGIGEESKIIIIILASFFPIFLNTLKGIKNCDNKLIEVGKSFNL
                     SKKRIFYKIIIPNSMLDIVVGLSLGLGYSFRAIIGAELIAASSGLGYLISDGKDMSRT
                     DVVLVGIFVIGFLGILSDYLFSKIITKFSKGKQVDLNG"
     gene            complement(9210..9920)
                     /locus_tag="KR231_002850"
     CDS             complement(9210..9920)
                     /locus_tag="KR231_002850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AIM24 family protein"
                     /protein_id="HBH0005211.1"
                     /translation="MFKFDVTNELMCIARGSGKFFAKKGAMVAFKGNFNFEKLLLGPS
                     NGGGLGRALLGHVQRSLTGEQMPIMVVEGEGEIYLAQNAYHVDVISIDPGDSIYVESE
                     NLLAFSEQLNYSVKLIGSGVISQKGLFTTHLVNKTGQNQDVAIITDGNPLILEGPCCV
                     DPDALVAWTGREPYPKVSKLSWKTFIGQTSGESYHMEFVEPGQIVIIQPSERLSGLKT
                     DSTPSDRMSSGGLRLGID"
     gene            complement(10100..10252)
                     /locus_tag="KR231_002851"
     CDS             complement(10100..10252)
                     /locus_tag="KR231_002851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FeoB-associated Cys-rich membrane protein"
                     /protein_id="HBH0005212.1"
                     /translation="MATFIIAAIVVVLMALAVMYMVKNSKKNGSSCGCGCSGCSSSKS
                     CHSAKR"
     gene            complement(10278..12434)
                     /gene="feoB"
                     /locus_tag="KR231_002852"
     CDS             complement(10278..12434)
                     /gene="feoB"
                     /locus_tag="KR231_002852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrous iron transport protein B"
                     /protein_id="HBH0005213.1"
                     /translation="MSIKIGLIGNPNCGKTTMFNGLTGSSQYVGNWPGVTVEKKGGKL
                     KGNKDVEIVDLPGIYSLSPYTLEEVVTRNFMLDDKPDAVINIVDASNIERNLYLTTQV
                     LELGIPTVIALNMMDIVNKNGDKINIKELSEVIGCPVVEVTAVKGQGIMEAAEKAVEL
                     ASSNNKLNFKLPFVDESKDAIEKIEKIIEEKTPYIDVETRWLAIKLFERDENVIQKLD
                     ISKTILNSIEEITRNCEDELDDDSESIITANRYEFISSIISSIIKKNRKGKETVSDKI
                     DKIVTNRILALPIFALIMWGVYYIAVSSLGTIATDWTNDVLFGEIIQGNVSNFLASLN
                     VAEWLQGLVVDGLIGGVGAVLGFVPQIMLLFLLLSILEDCGYMSRVAFIMDRIFRKFG
                     LSGKSFIPMLISSGCGVPGVMSTRTIENDRDRKMTIMLTTFIPCGAKIPIIALFAGAL
                     FGGASWVAPSMYFLGIAMIIICGIILKKTSLFAGEPSPFVMELPQYHIPSAKGVLIHM
                     WDRGKAFIIKAGTIIFVACGVIWFLQSFNWSLQMVDAGDSILASLGNIVAPIFAPLGF
                     GNWQSSVATVTGLVAKENVVGTFGVLFGISDATEQDPTLLASVASMFTVASAFAFMAF
                     NMLCAPCFAAIGAIKREMGSWKWTWITLGFQTLTAYIIALLINQVGSLVLGTGGSIAG
                     AIISIFIAVAVVFVVLTYSNKNMKKEKMGKLSYMKN"
     gene            complement(12534..12755)
                     /locus_tag="KR231_002853"
     CDS             complement(12534..12755)
                     /locus_tag="KR231_002853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrous iron transport protein A"
                     /protein_id="HBH0005214.1"
                     /translation="MNRLKDIKCGETVKVKKLEGEGATRRRIMDMGITRGVNIFIRKV
                     APLGDPIEVTVRDYELSIRKSDAEKIIVE"
     gene            complement(12768..12980)
                     /locus_tag="KR231_002854"
     CDS             complement(12768..12980)
                     /locus_tag="KR231_002854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrous iron transport protein A"
                     /protein_id="HBH0005215.1"
                     /translation="MMPLILSNTGEEVVIKKISGSDKTRTFLNSIGFVVGTNVKIVSK
                     IDGNLIIDVKDTRVALDKKMASRIII"
     gene            complement(13301..16198)
                     /locus_tag="KR231_002855"
     CDS             complement(13301..16198)
                     /locus_tag="KR231_002855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EAL domain-containing protein"
                     /protein_id="HBH0005216.1"
                     /translation="MKAFKKHFLILSLIFLLIISCFNNILCFADESENSKKIRVGYCD
                     DYGIISSSKEHSYTGYGYDYLREISKYTRWEYEFVKGSWEECLDRLEKGEIDLLGPLQ
                     KNDERNKLFNFPKLNSGYEYSVLYTKDSNNNMFYEDISSFKGMRVAVLRGNFHNIAFE
                     KYREENNFSVEYIYCNSIDELIESVNEKKADAFVCGSIINAKGMKIVSKFSVEPFYFA
                     TAKYKPNLVKELDYALKELKINDMYYELELYKKYFKREVNNSIAFTRQEMNFIKANPK
                     LTMVYDSEWSPVEYYDKESNSFKGISSNLMSIISKKCGIKFEYIKTKNYNESLDYIKS
                     GKANMLCGSINENDKAKRFNMKLTNPYINIPMIMVGKLDTNLNNDLNIALTSSYKSID
                     SYIEKSFENAKTTSYKSIESCLNAINEGKANLMILSSYQFDELLREGKSENLSVISVL
                     DTSYGMRIGVSNKTDPILVSILNKSIDKITEEELSDCIYSNTIDKPYKVPFGVIFKEY
                     SIQIISFVCILFLIAIKYIIYNKKKKEDYLKKIAYTDPLTGADSIDKFKINSNKLFAK
                     NNPEEYALFYIDVDKFKYINDMFGYDMGNDTLIHISNTIASELKEDEIFARVSADHFV
                     LLIKYKTDDDIKTRLNNIYNKVQILSNPKINYYKLILDCGIYKISKSDNDINTIMDRA
                     NTARKTIKGGHKNSFAFYDKEMHKKILKEKEIENSMVDALNNGEFIVYFQPKYSLSDY
                     QIIGAEALVRWDNPQKGLIPPIEFIPVFERNGFIVNIDFYVFEEVCKKIREWMDEGQK
                     VVPISVNLSRMHFVNSNFIEKFKLIVDKYKIPTRLIELELTETAVLDNIEGLLDTMNN
                     LKEKGFVISMDDFGTGYSSLNLLKELPVDILKLDRAFFTEKDESNNEKIVISNVIKMA
                     KELKMKVISEGVETISQVEFLKQIGCDMVQGYLFSKPMPVKEFEKIAFKKE"
     gene            complement(16525..17133)
                     /locus_tag="KR231_002856"
     CDS             complement(16525..17133)
                     /locus_tag="KR231_002856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dienelactone hydrolase family protein"
                     /protein_id="HBH0005217.1"
                     /translation="MVDNLIKYIHKSYVAIVVLHEIYGINSFIEDVCQKYYKYGYDVF
                     CPELLGEKRVFPYSKVQEAYDFFINNVGFDIYKKVEKLINDLKSEYKYVFVAGYSVGA
                     TIAWRCSEDSFCDGIICCYGSRIRDYMDVIPKCPTLLVFAKHDSFDVDSISYQLSRKQ
                     NIQIEILDANHGFIDRYSNNYSDIQTKVFTIKEKSFLSKYLA"
     gene            complement(17393..17938)
                     /locus_tag="KR231_002857"
     CDS             complement(17393..17938)
                     /locus_tag="KR231_002857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH peroxidase"
                     /protein_id="HBH0005218.1"
                     /translation="MKKFVCTVCGYIHEGDAAPAQCPVCKVGADKFEEMKGEKNWADE
                     HRIGVAQGVDEEIIEGLRANFVGECTEVGMYLAMSRQADREGYPEVGEAYKRIALEEA
                     EHAAKFAELLGEVVVADTKENLRVRVDAEYGATDGKLKLAKKAKELGLDAIHDTVHEM
                     CKDEARHGKAFLGLLNRYFGK"
     gene            complement(18056..19879)
                     /locus_tag="KR231_002858"
     CDS             complement(18056..19879)
                     /locus_tag="KR231_002858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH0005219.1"
                     /translation="MNLSTGNQKVSRLKKKEKPKDFKKTFKRIFMYFKKDKKITRFIF
                     LLVIIDSIISTVIPYTIGKVVDIIDIDTYSKSIFLKGIIILLSFYIIEFSVKLSKGIC
                     TARLSQSIVREMRSNLFLKFKNLPITFFDKSSTGDIMSRVTNDVDNISTGISNSLVQL
                     ITGILNILMTFIMMFVLSPILTFCSVILIPIVMFVSNFIAKRTRVFFKQQQVELGKLN
                     AHIEEMISNINVVKSFNYERKSVNDFKEVNDRLLNISLKSQIYTSLLMPIMNVISNIG
                     FATICIIGGILASKDIITIGVIASFLSYVRQFTRPLNELANLFNTLLSAIAGCERVFE
                     IIDEQEEQEVHNMFKSEINDNKDGNLNSHFVKGEIELKDVSFSYDSKKKILDNINLKI
                     KSGTSNAIIGETGSGKTTIINLITNFYHIDEGSIFLDGKDIYSINRNYLRTCFGVVPQ
                     EGYIFNDTVMENIRYGNLEATDEEVIYASKIANAHKFIVKMREGYSTVLSDRGEDLSE
                     GQKQLISIARAVLKNAPILILDEATSNIDIATEAKIQEAINNLTYGKTSIIIAHRLST
                     ISNCDNIIVLENGRIVESGNHKELIKLKGHYYRNILLTQGK"
     gene            complement(19892..21667)
                     /locus_tag="KR231_002859"
     CDS             complement(19892..21667)
                     /locus_tag="KR231_002859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH0005220.1"
                     /translation="MRYFKKYIKKYIVLFLTAVFFLTLEAFCDLAQPTIMAKIIDIGV
                     SNKNLDYILSTGAIMIGITFLGAIFAIIRSVISARVSQHFSYDLRQDVFEKINTYSLK
                     QIDKFGRASLITRITNDINQMQQFVNGMMRVFIKSPIMCIGSLIIAIKLNLKMSIIIL
                     IAVLIIFIIILLNMKIGYRLFKNVQESTDKVNSKLRQFLSGIKVVKLFCRYDYENQSF
                     EELNDELFKNSRKATTMMSFFRPTITIIINVSIIIILLIGRHLIYSGEIKIGIIVAYV
                     NYMTRILTSLIMISHVFNVFVRAKASYERISEVLVDENEEVIEREESLDVGEKDLKFV
                     NCDIIFENVDFSYNKNTDEKILKNVSFKIEEGQNIGVIGQTGSGKTSLVNLIQKLYII
                     DKGDIKIGGRSIYSISEESLRARIGVVFQNSSVFGKSILENVVMGNRDICKEDVVKSC
                     EIANANQFITKLENTYDEVLFQRGKNLSGGQRQRITIARAIAKKPQILILDDCFSAMD
                     INTETIIRKNIKEYISNLREKESKKCTVITISQKISSIIDCDKILVLDEGEVVGFATH
                     EDLLVSSPIYKKIFALKNLVSEDVN"
BASE COUNT         7211 a         3810 c         2181 g         8596 t
ORIGIN      
        1 agtatataaa agtagacata ttaattatgc ttaagttaag caatacaatt tggaattttt
       61 gaatttttaa atttactact cctaaaatac ttacaaaaac taatacaaga caccctactt
      121 tcaatatatt tataaattca tctgttttaa agctacttat ataaactata gaatatccaa
      181 atatccaaag taaaattatt ctatacatat ttatagaaac tgtatacaaa tttatattta
      241 aaagtgcaat aaccaaaaat aacccattag ctagtatata gaccttattc ttacttaaag
      301 ttcctttaga ttccatattc cccaccactt cttcattttt atatagtttt acctataaat
      361 atgttaccac aattcttcca aaaaatttgt cactttctag ttataaaaaa aaatgagtaa
      421 atatttttaa ttttactcat tttgtagatt ttgtatattc agtttaaaaa gctggaacta
      481 tacttccttt atattcatct tgtataaatt ttttaacttc tttactattc atagcctctg
      541 ataaagcctt aatcttatca ctatctttat tattttctct acaagctatt atatttacat
      601 atggagaatc acttgattct attactattg catccttagt aggatttaag ttagctgtta
      661 aagcataatt agaatttatt actgctccgt caacatcttt taatactgtt ggtaattgct
      721 ctgcattcat ttcttttatt actatatttt taggattttt agttatatct tttttagtta
      781 taagctctcc atcttttact tctatcaatt tattttttgc taataattta agtgctctag
      841 ctccattagt tgcatcattt ggcacagcta taacagctcc atcttttaat tcatctaatg
      901 acttaacttt ttctgaatag aatcccattg gctctatatg aactttagat gtataagtaa
      961 gtttatatcc tttctccttc acagtttcct ctaaaaatgg aatatgttga aagaagttag
     1021 catccaaaga cccttcatct aaagctgtat ttggaagtac ataatcatca aatattttta
     1081 cttctaaatc atatcctttt tcttttaaca aaggttttgc aacttccaat atctttgcat
     1141 gtggatttga tgaagctcct actagtattt ttttatcctc tttgtttgaa caacctactg
     1201 ctgatattgc tattgctgac accaatgcta ctgataataa tttctttaat ttcattttta
     1261 ctccccctct ttaaaatgtt tataattaat ttattttagt ttcttataag ccagatttcc
     1321 tactccctgg attatctgaa ctaatattat aagtgctatt acagtatata ccattactgc
     1381 tgtatcaaat ctttgatatc cataaataag tgctatatta cctaatcctc cagctcctac
     1441 tgcacctgcc atagctgtat aaccaagtat agatattatt gataatgtaa ttccagatac
     1501 tattgaaggc atagcttcct ttatcataac tttaaatact atttgtcttt ttgtagctcc
     1561 aaaagatttt gctgcttcta tcaatccttt atcaacttca tttaatgagc tttctataat
     1621 tctagcgata aacggtgctg ccccaatagt tattggcact attgcagcag tttcccctat
     1681 acttgttcca acgattaatc tagttattgg aatcattgca actataagta tcataaatgg
     1741 gaaacttcta aatatattta ctataaatcc taatgcacta tttattgtgc tatttggttt
     1801 taatccatct ggttttgtaa ctactaatat gattgctaat ataaatccta atattgttgc
     1861 cactatagtt ggtactataa ccatatacaa agtttgtaac aatgcatttg gaaatagtgt
     1921 tgttaaaaag tcaattaaac tattcattta tcatttcctc ccatcttatg cccttactag
     1981 ttagatattg ttttacttgc tctccacttt tatctgaaat gtttataata agtgaaccta
     2041 aaatatcatc tttaaattgt tctaatttcc caaatattat agacacatct atatttagtt
     2101 ctcttgccat agtcgtaata atagcttcat tagaaatatc tttagggaat agtatcttta
     2161 tatttgttcc ttttggcaat attatacttt cttcacctat taattttcta agtcctttag
     2221 tatttcttaa gaatatttct tctgtatctc ctacctctaa tacttctcca ttttccatta
     2281 ttgctactct tccacaaatc tgctttataa cttccatttg atgagttaca actattattg
     2341 ttattcccaa atttttattt atatcttcaa gcaatgaaag aattgacttt gtagtatttg
     2401 ggtctaatgc tgaagttgct tcatcacaaa gaagtacttg tggatttagt gctaaagctc
     2461 tagcaattgc aaccctttgt ttttgtccgc cacttagatt tctgggttta tcatttttct
     2521 tttcagatat tccaactact tctaataact ctaaaactct ttttttaatt tctgcctttg
     2581 agtatccaaa acattctaat ggcaatgcta cattatcaaa tacagttttt ctttcaagca
     2641 atgaaaagtg ttgaaaaatc attcctaact cttttcttaa atctctcatt tgcttttcat
     2701 tcaatgactt tacttcttta tcagaaacaa gtacactgcc ttcttggtat tcttctaatc
     2761 cgtttataca tctcagtagt gttgatttcc ctgcaccact atgacctatt attccaaaaa
     2821 tttctccaga ttctatttca atacttacat ctttaagcac ttgaatcttt ccataatact
     2881 tattaacatt ttttatgcta atcataaaat ttcctcccat atattctgct cagtttttat
     2941 gtttatcctc tcttatgtat tacaacaaaa taaaagcccg agtataaact caggcttaga
     3001 aagctattta tactcatcta tcaactatat tagttgcagg atttagcacc aatgtatata
     3061 aaatatactg gttgccgggt ttcaaagggc cagtccctcc accactcttg ataagacgtt
     3121 atttaattta attctattat catttgttgc tatgttatat atgatatatt cattaatagt
     3181 atttgtcaat aaatttattt aaatttttta ttttttatta tcgttaatta actattttta
     3241 attagttttc tagctcctaa cactttatat tttaatgtct atataactat agaacatcat
     3301 tataagaaat aaattaaata acatcaatct atctaaatca tctgtaaagt aaattaagaa
     3361 aattaacatt ttatccaaac tctatcctac tattaaataa aataatttaa atacaatgat
     3421 gattatatag ctctagtact ttagacttta ccaaatgttt aagttctata ggttctatta
     3481 ttgtagcatt tttcccaaaa gttaaaaaat attcagccac ccagttaagt gtagattttg
     3541 gtatatacat atctatgtat ccacctttag acaagatttt caaccctctt gccaacaaaa
     3601 attctgtttc acaacgtttt actccctcat ctgtcaaatt aattttaata tgataatctg
     3661 tacctacttc catattctta agataatcat gtatagaaga taaaacctta tatttcttac
     3721 ttgataagtt ttctatactc aaaatcttca caattctgtc tacacgaaat tccttaatag
     3781 atgctgattt tatacagtaa gctggacaat accaaagtcc attcatggca tacaaaccaa
     3841 taggaacaat ggtacgtaca ctattttttt gctttgatga atattcaatt ttaattgtag
     3901 attcattcat tactatatta aacaattctt tcaataatgg tgttgaacag tgcctatctg
     3961 gtgtccaaaa aacaaattta cgccttatat tctcaatatt atattgaata tcatttggta
     4021 tacaatttaa aaattttttt aaaacagaaa tagtttcttg ctcaaatggc aaatcattat
     4081 aatattctag tgactgatat gcaaagaata tagattttac ctcactttct gaaaatgcaa
     4141 tcggtggaag tatacgctct ttaagtacat gatatccacc agccgctcca acttttgaat
     4201 ataatggaaa tccaatactc tccagcacct gtaagtctct taatatagta cgttttgata
     4261 cagaaaattc ttctgctaat tctcctgctg taaaacttct ttttgcattt attgttatca
     4321 tcagttcaat taaacgctca gctcttgaca tatttatact cctaatttaa atatagtgac
     4381 aataattgtc actattatat gataagatat tcttacattt aaagcaataa taatagtaaa
     4441 gaaagaaggg actgatactt tatggaaaat aatactatta aggctgatga tattatcaat
     4501 tattgtctat caaacttaga tgatgtttta ttaatgaata gttgggggga acgagcaatt
     4561 tactacaatc ctaatggtat tttaaagcga ggagtatatg ttcttaccat taaagaaaaa
     4621 gacagtaatc atgataaagg ttcgttggtt agtcgcccaa atgtataccg tgtgaatata
     4681 ggattaaaaa aagaaacttt tattgaaatg tttggatata ttccaaaacg tccaggtgta
     4741 ggtcaaatag ttgatatgga ttttgatttt acaaaattgg acacaatcat gccacatcct
     4801 atctactcat ggatgggatg gatatgcgtc ctaagcccta ctgaaaagac atttgagaac
     4861 tttaaaactt taataggaga atcttacaat tttgcaaaac aaaaatttaa aaagagaaaa
     4921 aacaagtaaa aacgtatgaa aataatccct aaataaatta taataaaaat attaaggtta
     4981 caagataaaa attaatatct taataacatg caaaaaagcg aagccaaaaa atgtattatt
     5041 tataaggctt cgctatatct caaataattt atttcaaatt tcaaaactat ttattctatt
     5101 atttcttatt atttcctgtt attcctaatc tatcattcat atcttttatc atttttctaa
     5161 aaccactacc tatatcattt ccaacatctt cagttccatg aactaatttt ataaagtcat
     5221 tttgaccttt tttcatatct tcatcagata ccttatctaa tttttctatt ctcttatcta
     5281 tgtcttttac taatctttcc ccttcagcga ttaggtcatc attcattttc tttaactctg
     5341 tatcttctgt tttaccatct tttttaagag atgttacaaa tgattgtatt ttatctctac
     5401 tatctttata tgcagccttt acatcactta gatatttttc atttcctgga tattctttat
     5461 ctttaaactg attatttata ctttctggag tatcataaat agaatatcta tttagacctg
     5521 ctatataatc attatagctt gttgaataat aattcatata tccttcatta ttatttacag
     5581 attcattagg attttttcct gtattttcac ttggtttttc attattttta gtacatgcag
     5641 ttatacctat agctaatact agtgctaatc ctacaaataa agttcttttt aatttcattt
     5701 ttattaccct cctagatgtt ttatactata aaaaatttta ataattttct ttcttaattt
     5761 agtatttcta tatttttata ttttatttac taaaattaaa caagttataa tttatttttt
     5821 tggaaatcat aatgaataaa taattaaata aaaaaattat aattttatta ttgatattga
     5881 ttatcattca tagtataatc taattacttg atattaattt tcatttgaag gaggttatct
     5941 tttatgtctt gttgtaattc acaattttgt tgtaaaaata aaattgaatc atcatatata
     6001 aaatggcttt tagaagtttt aggtccagtc tttttaggct ctaaacctgc tgaaataata
     6061 aatatttcgt ttactgatgt aaatagagag gaaaaaatta atgatattta taaatatcta
     6121 tataaatgta agaaaataga ttttatagtt attgataaag aaaaaaaggg attaaaaatc
     6181 ttatttgtaa ataaaaaagc attatcagaa aaattaaaat gtaaaaaaac agtaaacttt
     6241 ttaaagtttt taggatacaa acaaaatacg aatgttaatg cttatttaga gcatttagta
     6301 gataaactta agagtgatgt ttttcctgat gaaataggta tttttttagg atatcctctt
     6361 aaagatgtga ttggatttat gggatatagt aattatgaag tttctatgat taaatattgg
     6421 aaagtttatg gtgacacaaa acaatccgag gacacatatt cgaagttttt acttcaccgt
     6481 aagaaaatga gaaaattact agactacata agtgtagata aaatagtaag ctgtttttaa
     6541 ttgtattttt gtataataat aaaaatacac cctcttttac catatagttt ccataataaa
     6601 taagggtgta ttttccactt taatatttta aagtattcta attttgattg tacaacatat
     6661 ctttaatatt tattttcttt tgttgcattc cattagacat taaaaattcc tgtgtatctt
     6721 ctaattcttt tatatccttg tccgttattt tagaactaaa gtcataccaa gaatacattt
     6781 cttttgtttc atctaaagat aaaccaactt ctttagatac aacatccatc acttcatcct
     6841 tgttttcatt catatatttt aaagtttctt catgaacctt cataaatctt tttactaatt
     6901 caggatattt ttcagcaaag tcatcactta cagcagtaac tattattcca cttactaatc
     6961 cttctccatt tacaatcatt ttggcacctg aatttatcgt tttcaatgcc actggacctg
     7021 caagcattgc tacatcagca cttttacttt ctaatgcaga agcagcacta ggaatatcca
     7081 tatttacata ttcaacatca tctatagtat agccttcttt agcaagtgca gcaatcaaca
     7141 gttgatgaag tatagtccct tttggaccta caattttttt accttttaag tcttttatag
     7201 atttaatatt atcattatta gttataagca tatatccttt tggtgaacgg ctataaatat
     7261 tcgtaatttt aagaccaaca ccatttgatg cagctattat tgcagacgtt cctcctaatg
     7321 catgtaaaaa gtctagctca cctgctgcta atgcttgagt ttgctctggt cctgttgtca
     7381 attcatggaa attgactttt atattgtcct ttttaaattc ctttccaaat aaatcatcct
     7441 ttttttctaa tatactagga acattaagtg gtgattttac ataagttaaa tttatttcct
     7501 taggtaaact agcctctttt tttgcaggtt catctttctt atcatttgtt gttgaacatc
     7561 ctacagtccc aaccaacacc attattaaag atgtcattac tgctaaaatc tttttgtttc
     7621 ttttaatcaa ttaaaactcc cccaattccc ttaatatttc ttttttcaag tttatataat
     7681 agtttttagt taaatctcta ttatattcat cttcgacact aaattgttta atccttttat
     7741 ttttactaaa aacaattatt ttctttgcta tttccatagc ttcttcaata ttgtgagtta
     7801 caaatactac acctttttta gtatttttat ggatatttac aacttctttt tgcatttttc
     7861 ttcttgtgaa gtaatctagt gctgcaaatg gttcgtccat cagcaaaata tcgggattga
     7921 aggaaagtgc tcttgctata cttactctgt gagccattcc tcctgataat tcatttggat
     7981 atgagttttt aaacttttca agcttcatca tttttaaata cttgtctaaa tcaactttat
     8041 ttctattatc tttttcagta tgtaaaagta tattttcact tacattcagc catggcataa
     8101 gtctactttc ttgaaatacc attcctactt ttggagtaca ctttttatca ttattaaaaa
     8161 aatatatgtt tccactagta gcattttcaa gccctactaa aattctaagt agcgttgttt
     8221 tcccacatcc actttcacct aatataacag ttatctcttc actagatata tttaaagata
     8281 tattatcaag aactaaatgc tctttattat caactaaata tttcttatat atattctcta
     8341 gcaaaaatcc acttctaacc atttaaatca acctgcttcc ctttgctaaa ttttgttatt
     8401 atctttgaaa atagataatc tgaaagtata cctaaaaatc caataacaaa aattcctacc
     8461 aatacaacat cagttctaga catatctttt ccatcagaaa tcaaatatcc tagtcctgaa
     8521 gaagctgcaa taagctctgc tccaattata gccctaaaac tatacccaag ccctaaacta
     8581 agtccaacaa caatatccag catagaatta gggattatta ttttataaaa aattctcttt
     8641 ttagataaat taaaagattt acctacttct attaatttat tgtcacaatt ttttatacct
     8701 ttcaatgtat ttaaaaatat tggaaaaaag gatgccaaaa taataattat aattttagat
     8761 tcttcaccta taccaaacca taaaataagc attggcacca aagctagtgg aggtgtactt
     8821 cgcataaatt caaatagtgg tttgaaatat tcatacattt ttttatttac tccaaataaa
     8881 actccaagtg gtatagccat caatgaactt attaaaaaac ctattaatat ccttcttaca
     8941 ctggcataaa catttaagaa aatagaaccg tcatatatca tttttataaa agtatctaag
     9001 actatttcag gaggaggcag aatatagcta ctccatatac ccaaaacaca tactatcttc
     9061 cataaaatta aaattattaa aaaaatataa tatcctttaa gccttttatg aattttctca
     9121 aacatataaa actcctttta acatatctat ccctgctacc ctttttattt tttaatatct
     9181 taaataataa ttaagctata tcataagatt taatctatgc caagtcttaa tccacctgaa
     9241 ctcattctat cagaaggtgt agaatctgtt tttaagccag acaatctttc agatggttgt
     9301 ataatgacta tttgtccagg ttcaacaaat tccatatgat aagattctcc tgaagtctga
     9361 ccaataaaag tcttccatga tagttttgat actttaggat atggttctct tccagtccaa
     9421 gctactaatg catctgggtc aacacaacaa ggtccttcaa gaattagagg attaccatct
     9481 gttattatag caacatcttg attttgacct gttttattta ctaaatgtgt agtaaaaaga
     9541 cctttttgag atattacccc tgaaccaatc aattttacac tgtaatttaa ttgttcagaa
     9601 aatgccaata agttttcact ctcaacataa atggaatcac ctgggtcaat tgatattaca
     9661 tctacatggt aagcattttg agctaggtaa atttcacctt caccttcaac caccattatt
     9721 ggcatttgtt ctcctgtcaa tgacctctga acatgaccta ataatgctct tcccaatcca
     9781 ccgccattac ttggacctaa cagcaatttt tcaaaattaa aatttccttt aaaggctacc
     9841 atagcacctt tttttgcaaa aaatttacca cttccccttg ctatacacat aagctcgttt
     9901 gtaacatcaa atttaaacat aatattcact tatattgctt aatttagcaa taatccctcc
     9961 taatcatata tttatatata attatacagt aaaattacag catagtctaa cctacttcaa
    10021 atatgaaatt tgttatttat acaaaaaata agaacctgat aataaagcaa tttaactttt
    10081 tatcaggctc ttatcctatt tatctcttag cgctatgaca actcttacta cttgagcatc
    10141 cagaacaacc acatccacaa ctgctaccat tcttttttga atttttaacc atatacatta
    10201 cagctagtgc cattaatact actacaatag ctgctataat aaatgtagcc atattcatca
    10261 ctccttattt atatgaatta atttttcata taacttaatt tacccatttt ttcttttttc
    10321 atatttttat ttgaataagt taaaactaca aagactactg ctactgctat aaatatagat
    10381 attattgccc cagcaatact tcctccagta cctaaaacta aacttccaac ttgatttata
    10441 agaagagcaa ttatatacgc tgttaaagtt tggaatccta atgtaatcca tgtccatttc
    10501 catgaaccca tttctctttt tatggctcca atagctgcaa aacaaggtgc acaaagcata
    10561 ttaaatgcca taaatgcaaa cgcactagct actgtaaaca tgcttgcaac tgaagcaaga
    10621 agtgttgggt cttgctctgt tgcatctgat ataccaaata aaactccaaa tgttccaact
    10681 acattttcct tagctactag acctgtaact gttgctactg atgattgcca atttccaaat
    10741 ccaagaggag caaatattgg tgcaactata tttcctaagc tagctaatat actatctcca
    10801 gcatctacca tttgtaatga ccaattaaat gattgtaaga accagattac tccacaagca
    10861 acaaatataa ttgttcctgc tttgattata aatgcttttc ctctatccca catatgtatt
    10921 aaaacacctt ttgcacttgg aatatgatat tgaggtaatt ccataacaaa tggagatggt
    10981 tctcctgcaa ataaactagt tttctttaat ataattccac aaatgattat cattgcaata
    11041 cctaagaaat acattgatgg agctacccat gaagcacctc caaataatgc ccctgcaaat
    11101 aatgctatta ttggaatctt agctccacat ggaatgaatg tagttaacat aatagtcatt
    11161 tttctatctc tatcattctc tatagtacga gttgacataa ctcctggaac tccacaacct
    11221 gaacttataa gcattggtat aaatgatttt cctgaaagac caaacttacg gaaaattcta
    11281 tccattataa aagctacacg tgacatgtac ccacaatctt ctaatattga taataataag
    11341 aataaaagca tgatttgtgg tacaaatcct agtactgctc caactccacc aattagacca
    11401 tcaactacaa gtccttgtaa ccactctgct acatttaaag aagctagaaa attacttaca
    11461 ttgccttgaa taatttctcc aaacagtaca tcatttgtcc aatcagttgc tatagtaccc
    11521 aatgaactta ctgctatata gtaaactccc cacattataa gtgcaaaaat aggtaatgct
    11581 agtatacgat ttgttacaat cttatctatc ttatctgata cagtttcctt accttttcga
    11641 ttcttcttta ttatacttga aattattgaa ctaataaatt cataacgatt ggctgttatt
    11701 atactttcac tatcatcatc caattcatct tcacaatttc tagttatttc ttcaatacta
    11761 ttcaatattg ttttagaaat atcaagtttt tgtataacat tttcatctct ctcaaatagc
    11821 tttatagcta accagcgtgt ttctacatct atatatggag tcttttcttc tattattttt
    11881 tcaatttttt ctattgcatc cttactttca tcaacaaagg gtaatttgaa atttaattta
    11941 ttgttactac ttgcaagttc aactgccttt tcagcagcct ccataattcc ttgaccttta
    12001 actgctgtta cttctaccac tgggcaacct ataacttcag atagttcttt aatatttatc
    12061 ttatcaccat tcttatttac aatatccatc atattaagag ctataacggt cggtatacct
    12121 agctctaaaa cttgagttgt aagatataaa tttctctcta tatttgatgc atctacaata
    12181 tttattactg catccggctt atcatctagc ataaaattac gtgtaactac ttcttctaat
    12241 gtatatggag ataaagaata aatacctggt aaatctacta tttccacatc tttatttcct
    12301 tttaattttc cacctttttt ttcaactgtt actcctggcc agttaccaac atattgtgat
    12361 gagcctgtaa gcccattgaa cattgttgtc ttaccacagt taggatttcc tatgagacct
    12421 atttttattg acatttccat tccctccatt attatttaaa tacatcacta ttcatgatat
    12481 agaaaatcat tctcattata taattacatt aactctactc taattaatct ttattattcc
    12541 acaataattt tttctgcatc tgacttacga attgatagtt cataatctct gactgttacc
    12601 tcaattgggt caccaagagg agctactttt cttataaata tattaacgcc tcttgtaatc
    12661 cccatatcca ttatacgtct tcgtgtagct ccttctcctt ctaacttttt gacttttaca
    12721 gtctctccac acttaatatc cttcagtctg ttcatgtcat tacctcccta tattattatt
    12781 ctacttgcca tttttttatc taatgcaact ctagtatctt ttacgtctat tattaagtta
    12841 ccatctatct tagaaactat tttaacattt gtacctacta caaaacctat actatttaaa
    12901 aaagtcctcg tcttatcact tcctgaaatt ttctttataa ctacttcttc acctgtattt
    12961 gatagtatca atggcatcat ataatatccc tcctcttaaa ctaatttaaa tctacaagca
    13021 atcgttatct tatatataaa ttacaatacc ttaaatctta atctattaaa ataatatcct
    13081 attttttcct tctttttaca attcctaatt ttgatttaag tctatcacaa tagtatattt
    13141 tttgcaagtg attattgtat tcttttgatt ttttttctca tttgatttat tttattaata
    13201 aaatcgtaaa aattaataca aaaataaaga tgctctaaaa tagtatactc aactaatatt
    13261 aaagcacctt tattatatat atcattactt acacattgct ttattctttt ttaaaagcaa
    13321 ttttttcaaa ctcttttaca ggcattggct tagaaaacaa atatccttgt accatgtcac
    13381 acccaatttg ctttagaaat tctacttgcg aaatagtctc tacaccttct gatattactt
    13441 tcattttcaa ttcctttgcc attttaatga cattagatat aacaattttt tcattattac
    13501 tctcatcttt ttctgtaaaa aatgctctat ctagttttaa tatgtcaaca ggcaattctt
    13561 ttaaaagatt aagagaggaa tatcccgtac caaaatcatc catagagatt acaaatccct
    13621 tttctttcaa attgttcatt gtatcaagta acccttctat attatctaat actgctgttt
    13681 ctgttagctc taattctata agtcttgtcg gaattttgta tttatctaca attaatttaa
    13741 acttctctat aaaattacta tttacaaaat gcattcgaga caagtttaca gatataggta
    13801 ctactttttg tccttcatcc atccattctc taatcttttt acacacttcc tcaaatacat
    13861 agaaatcaat atttacaata aaaccattcc tctcaaatac aggaataaat tctattggtg
    13921 gtattagacc tttttgtgga ttatcccatc gaacaagagc ctctgcccct ataatttgat
    13981 aatctgaaag actatattta ggttgaaaat aaacaataaa ttctccatta ttaagagcat
    14041 ctaccattga attttcaatt tctttctctt ttaatatttt tttatgcatt tccttatcgt
    14101 aaaaagcaaa tgaattttta tgaccacctt ttatagtttt tcttgcagta ttagctctat
    14161 ccataatagt atttatgtca ttatcacttt tacttatttt atatatacca caatctaaaa
    14221 tcaatttata atagtttatt ttaggattac taagtatttg aaccttattg taaatattgt
    14281 ttaaccttgt tttaatatca tcatctgtct tatacttaat aagaagaaca aaatggtcag
    14341 cagaaactct tgcaaaaatt tcatcttcct ttaattcact tgcaatagta tttgatatat
    14401 gtatcaaagt atcatttccc atatcatatc caaacatatc atttatatat ttaaatttgt
    14461 caacatctat ataaaacaat gcatattctt ctggattatt tttagcaaac agtttattcg
    14521 aatttatttt aaatttatct atactatctg ctcctgtcaa tgggtctgta tatgctatct
    14581 tctttagata atcctctttc ttctttttat tataaattat atatttaata gcaattaaga
    14641 ataaaataca tacaaaagaa ataatttgta ttgaatattc tttaaaaatc acaccaaatg
    14701 gtactttata aggtttgtca atagtattag aatatataca atcacttaat tcttcttcag
    14761 taattttgtc tattgattta tttaaaatag atactaatat agggtcagtt ttatttgata
    14821 cccctatacg catcccatag cttgtatcta aaacagatat aacagataaa ttctcactct
    14881 ttccttctct taaaagttca tcaaactgat aagaactaag tatcattaag tttgctttac
    14941 cttcatttat agcgtttaga caactttcta tactcttata agatgttgtc ttagcatttt
    15001 caaaactttt ttctatataa gaatcgatag acttataact actcgttaaa gcaatattta
    15061 aatcattatt gagattggta tccagttttc ctaccataat cattggaata tttatgtatg
    15121 gatttgtcaa tttcatatta aatcgttttg ccttatcatt ttcattgatt gagccacata
    15181 gcatatttgc cttaccactt tttatgtaat caagactctc attataattt tttgttttaa
    15241 tatattcaaa ttttatacca catttttttg atataattga cattaaattg gaacttatac
    15301 ctttaaacga attgctttcc ttatcataat actctacagg agaccactct gaatcatata
    15361 ccatagtaag ttttgggttt gctttaataa aattcatttc ttgccgagta aatgctatgg
    15421 aattattgac ctctcttttg aaatattttt tatataattc caactcataa tacatatcat
    15481 ttatttttaa ttcttttaaa gcataatcta attcttttac caaattaggt ttatattttg
    15541 cagtagcaaa ataaaaaggc tctactgaaa atttgctaac tattttcatt cctttagcat
    15601 ttataatact tccacagaca aatgcatctg cctttttttc attgacagac tcaattaatt
    15661 catcaataga attacagtag atatattcaa ctgaaaaatt attttcttct ctatacttct
    15721 caaatgcaat attatgaaag tttcctctaa gtacagctac tctcattccc ttaaaggaac
    15781 ttatatcttc ataaaacata ttattgttac tatcttttgt atatagtaca ctatattcat
    15841 atcctgaatt tagtttagga aaattaaata gtttatttct ttcatcattc ttctgtaaag
    15901 gtccaagtaa gtctatttca cctttttcta gtctgtctaa acattcttcc caagaccctt
    15961 ttacaaattc atattcccat cttgtatatt ttgagatttc tcttagataa tcataaccat
    16021 atcctgtata agaatgctct tttgatgagg atattattcc gtagtcatca caatatccaa
    16081 ctcttatttt ttttgaattt tcagactcat cagcaaagca tagtatattg ttaaaacatg
    16141 atataataag taaaaatatc aaagaaagta tcaagaagtg ctttttaaat gctttcatat
    16201 ttaaaaacct ccaatttgcc aacttacttt aacttatttg gttttctagt tgtaactact
    16261 tttattgtaa tggtaaatat atcaaattgc aatattctca tataatattc ttattcaact
    16321 ataatgaatt tattattatc tatttaaata cactatctaa tattagtttc ttataagtca
    16381 taaaagcaca actaacacta taattctagt gattaatttt atttcaaaaa atataataac
    16441 actactaata ttttaaatat caatagtgtc ataaaaactt ttcagattaa ttaaatcttt
    16501 ctatatattt tataataatc taaatcatgc taaatattta gacagaaaac ttttttcttt
    16561 aatagtaaat acttttgttt gaatatcaga ataattattt gaatatctat ctataaaacc
    16621 atgatttgca tctaaaatct caatttggat attttgtttc ctagaaagtt ggtaagaaat
    16681 agaatcaaca tcaaatgaat cgtgctttgc aaatactaat aaggtaggac attttggaat
    16741 tacatccatg taatctcgaa tccgagagcc ataacaacaa attatgccat cacaaaaaga
    16801 atcttcactg catctccatg caatagttgc tcccacacta tacccagcaa caaatacata
    16861 tttatactct gattttaaat catttataag cttttcaact tttttataaa tatcaaaacc
    16921 aacattattt ataaaaaaat catatgcctc ttggactttt gaatatggaa aaactctttt
    16981 ttctcccaga agttcaggac aaaatacatc atatccatat ttataatact tttgacaaac
    17041 atcttctata aagctattaa tcccatagat ttcatgtaaa acaacaatag ctacataact
    17101 tttatgtata tactttatca gattatccac cacctttaca aaacagcaaa ttttttatac
    17161 ttagtttaat atattcttct ttacatgtca atttactttt ctaaaatcaa atttattttt
    17221 ggattaatca tttattttta aaagttgtgc attattacta ttaaattatt ctctattatt
    17281 aaaaatataa tcgttagaaa taaaaaataa agtacaaata attaaaaaat atctcactca
    17341 taactttaaa aattgtaagt gagatactcc taaaatctac tttatattaa atttattttc
    17401 caaaatatct atttaataat cctaagaatg ctttaccatg tctagcttca tctttacaca
    17461 tttcatgtac tgtatcatgt atagcatcta atcctaattc ttttgctttc ttagctaatt
    17521 ttaattttcc atcagttgca ccatactcag catcaactct aactcttaag ttttcttttg
    17581 tatctgcaac tacaacttct ccaagaagtt ctgcaaattt agcagcatgt tcagcttctt
    17641 caagagctat tctcttataa gcttctccta cttctggata accttctcta tcagcttgtc
    17701 tactcattgc taaatacatt cctacttctg tacactcacc aacaaagtta gctcttaatc
    17761 cttcgattat ttcttcatct acaccttgag ctactcctat tctgtgctca tcagcccaat
    17821 ttttttcgcc tttcatttct tcaaatttat cagctccaac tttacatact ggacattgtg
    17881 ctggtgcagc atctccttca tgtatatatc cacatactgt acaaacaaat ttcttcataa
    17941 ttactttcct cctaaatttt atatatcaaa ttaaattttt tatttattaa gttagtctat
    18001 atatacccgc accatatacc tttaaacaat ttttttaaaa gttttttcta aatacttatt
    18061 ttccctgtgt caataatatg tttctataat aatgtccctt taattttatc aattctttat
    18121 gatttcctga ttccacaatt ctaccatttt ctaaaactat tatattatca caatttgata
    18181 tggtacttaa tctatgagct ataattatac ttgtctttcc ataagttaaa ttatttattg
    18241 cttcttgaat tttagcttct gttgctatat ctatgttact tgtagcctca tccaaaataa
    18301 gtattggagc attttttaat actgctctag caatacttat taattgtttt tgaccttcac
    18361 ttaaatcttc acccctatcc gataatacag tactatatcc ttcacgcatt ttaactataa
    18421 atttatgtgc atttgctatt ttactagcat atataacttc ttcatcagta gcctccagat
    18481 ttccatacct tatattttcc ataactgtat cattgaatat ataaccttct tgtggaacta
    18541 ctccaaaaca agttctcaaa tagtttctgt taatagagta tatatcctta ccatctaaaa
    18601 atatacttcc ttcatctata tgataaaaat ttgtaattag atttataata gttgtttttc
    18661 cacttcccgt ctctcctatg atggcatttg atgtgccaga tttgattttt aggtttatat
    18721 tatctaaaat tttctttttt gaatcataag aaaaacttac atctttaagc tcaatttctc
    18781 cctttacaaa atgagagttt aaattaccat ctttattatc gttaatctca cttttaaaca
    18841 tgttatgcac ttcttgctct tcttgttcat ctataatttc aaaaactctt tcacatccag
    18901 ctatggctga aagtaatgta ttaaatagat ttgctaattc atttaaaggt cttgtgaatt
    18961 gtcttacata acttaaaaaa ctagctataa cccctatggt tataatatct ttagatgcaa
    19021 gaatgcctcc tataatacat atagttgcaa atcctatatt actaatcaca ttcataatag
    19081 gcattaaaag agaagtgtaa atttgcgatt taagggaaat atttagaagt ctatcattga
    19141 cttctttaaa atcatttaca gattttcttt cataattaaa agattttact acatttatgt
    19201 ttgatatcat ttcttcaata tgtgcattta gttttcccaa ctcaacttgt tgttgcttaa
    19261 aaaaaactct agttctcttt gcaataaaat tactcacaaa cattactatc ggtattaata
    19321 ttacactgca aaaggttaaa attgggctta atacaaacat cataataaaa gtcatcaata
    19381 tgtttaagat tcctgtaatt aactgtacta atgaatttga tattcctgta ctgatattat
    19441 cgacatcatt tgtcactcta ctcataatat ctccagtaga acttttatca aaaaaggtta
    19501 ttggtagatt tttaaatttt aaaaataaat tacttctcat ttctctgact atactttgag
    19561 ataatctagc tgtacatatt cccttagaca gtttaactga aaactcaatt atataaaatg
    19621 aaagtaaaat aattattcct tttaagaaaa tggattttga ataagtatcg atatctatta
    19681 tgtcaactac ctttccaata gtatatggta ttacagttga tataattgaa tcaattatta
    19741 ctagcaaaaa aataaatcta gtaatcttct tatctttttt aaagtacata aaaattcttt
    19801 taaacgtttt tttaaaatct ttaggctttt cttttttctt taatctactg accttctgat
    19861 ttccagtact taaattcaat atacttcctc cttaatttac atcttcactt actaaatttt
    19921 tcaacgcaaa aattttttta taaattggag aactaaccag taaatcttca tgtgtagcaa
    19981 atccaaccac ctcaccctca tccaagacta aaatcttatc acagtcaatt atagaactaa
    20041 tcttttgtga aatagttatt acagtacatt tcttactttc cttttctctt aaattactta
    20101 tatactcttt tatattcttt cttataattg tctctgtatt aatatccatt gcactaaaac
    20161 aatcatcaag aattaatatt tgtggttttt tggctatagc tctagctata gtaattcttt
    20221 gtctctgtcc tcctgataaa tttttacccc tttggaataa aacttcatca taagtatttt
    20281 cgagttttgt tataaattga tttgcatttg ctatttcaca tgattttaca acatcctctt
    20341 tgcatatatc tctatttccc ataactacat tctccaatat actttttcca aacacactac
    20401 tattttgaaa tactacacct attcttgccc ttaaactttc ttcagaaata ctgtatatac
    20461 tacgtcctcc aatcttaata tcacctttat caattatata taatttttga attaaattta
    20521 ctaaagaagt ctttcctgaa ccagtttgac caatcacacc aatattttga ccttcttcta
    20581 ttttaaagga tacgtttttt aatatttttt catctgtatt tttgttatac gaaaaatcta
    20641 cattttcaaa aattatatca cagtttacaa actttaaatc tttttctcca acatctaaac
    20701 tttcttctct ctcaattact tcttcattct catcaaccaa aacctcactt attctctcat
    20761 aagatgcttt tgccctaaca aaaacattaa aaacatgtga aatcattata agagatgtta
    20821 atattctagt catatagttt acataagcaa ctataatccc aattttaatt tctcctgaat
    20881 aaattaaatg ccttccaatc agtaatatta ttattatgga aacattaatg attattgtaa
    20941 ttgtcggtct aaaaaatgac atcatagttg tagcttttct actattttta aaaagttcat
    21001 catttaactc ttcaaagctt tggttctcat aatcgtatct acaaaatagt ttaactactt
    21061 ttattccact taaaaactgt cttaattttg aatttacttt atctgtactt tcttgtacat
    21121 ttttaaataa tctataccct atcttcatat taagcaatat tataataaat ataattaaaa
    21181 ctgcaattag aataattatt gacatcttta aatttaattt tatagctata attaaacttc
    21241 ctatacacat tattggtgac tttataaaaa ctctcatcat tccattaacg aattgttgca
    21301 tttgattgat atcattagta attcttgtta ttaatgaagc tctaccaaat ttatctattt
    21361 gttttaatga gtatgtattt atcttttcaa atacatcctg tcttaaatca taagaaaaat
    21421 gctgagaaac tcttgccgag attacacttc ttattattgc aaatattgca cctaaaaaag
    21481 ttatacctat cattatagct cctgttgata gtatgtagtc taagttctta tttgaaaccc
    21541 ctatatctat tatttttgcc attatagttg gttgagctaa atcacaaaaa gcttccaatg
    21601 ttaaaaaaaa tactgctgtt agaaataata ctatatattt ttttatgtat tttttaaaat
    21661 acctcattca atcatccctt catagaattt tctcattacc aaaagtatat cataatggct
    21721 aatttaattg attatatcaa ttataaatat ttgatttatt attaattttt ataccatata
    21781 ttttataaat tatttgtt
//
LOCUS       DAEPHU010000070        21081 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 01A10CD0081
            SAMN05941466-rid12468953.denovo.070, whole genome shotgun sequence.
ACCESSION   DAEPHU010000070 DAEPHU010000000
VERSION     DAEPHU010000070.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941466
            Sequence Read Archive: SRR6291087
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 21081)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21081)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068158.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 22:43:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,892
            CDSs (total)                      :: 3,805
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 87
            rRNAs                             :: 8, 1, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 55
            CDSs (without protein)            :: 55
            Pseudo Genes (ambiguous residues) :: 0 of 55
            Pseudo Genes (frameshifted)       :: 21 of 55
            Pseudo Genes (incomplete)         :: 28 of 55
            Pseudo Genes (internal stop)      :: 16 of 55
            Pseudo Genes (multiple problems)  :: 8 of 55
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21081
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941466-rid12468953.denovo.070"
                     /strain="01A10CD0081"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            complement(159..902)
                     /locus_tag="KR231_002860"
     CDS             complement(159..902)
                     /locus_tag="KR231_002860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3298 domain-containing protein"
                     /protein_id="HBH0005221.1"
                     /translation="MENYQSTNTCTYNILYVQFNEDFERSKYFSYDVKYPVIYNIRNQ
                     STYVNPVILNNINNAVRMTVNNFKNGLQEEEREYNNATSQNSLPKQSYWVSTSYAVTF
                     NKNYVLSMILNLMGFANNYGPKYNTLNNYNIDLTTGKELLLNDIFRDGVDYINIITDY
                     IKSQINENREMYYSNVELVIPEDQAFYLTDNGIIIYFGVDEIAPESFGIPKFELKFSD
                     FGNFINLRFYCISPDIYVQSRGRAKHFMG"
     gene            1070..1942
                     /locus_tag="KR231_002861"
     CDS             1070..1942
                     /locus_tag="KR231_002861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HBH0005222.1"
                     /translation="MLLLADKWKDYELIDMGNGEKLERWGSYVLRRPDPQVVWPMESE
                     WALWKNPHGHYHRSNKGGGQWEHKKRYPEQWTINYKNLKFHIKPTGFKHTGLFPEQAA
                     NWDWMIEKIKKANRPIKVLNLFAYTGGATVACASAGAEVCHVDAAKGMVNWAKENIEL
                     SGLKNQTVRFIVDDVVKFVEREIRRGKKYDAIIMDPPSYGRGPKGEVWQIEEKLYSFV
                     DLCMGVLSDNPLFFLINSYTTGFSPIVLENVLSTTIGKKTNTGDIYGGELGIPASRDG
                     KILPCGIFGRWEKK"
     gene            1942..2607
                     /locus_tag="KR231_002862"
     CDS             1942..2607
                     /locus_tag="KR231_002862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HBH0005223.1"
                     /translation="MIKVIYEDNHLLVVEKPVNILSQGDNTNDKDMVNLLKDYIKKKY
                     NKPGNVYIGLIHRLDRPVGGVMVFAKTSKAASRLSEQVRSKTFKKTYLAVVHGKIKSN
                     SDILKDFLYKNKKTNMVTVVKKSHKDAKEAELNYNVLDFKENLSLVQVNLKTGRSHQI
                     RVQFASRKHPLYGDQRYGKEINKIGQQISLWSNKIEICHPTTKEKMEFTCHPPDKYPW
                     NIF"
     gene            2628..3485
                     /locus_tag="KR231_002863"
     CDS             2628..3485
                     /locus_tag="KR231_002863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HBH0005224.1"
                     /translation="MSKKFSIGEMSKLHKISIQTLRYYDQIDLFKPVHVDQESNYRYY
                     SIDQFSQLDIIKYLKYLGMPLKEIKSKLDENNEEILKLLTNKINIVDEKIKELELIKK
                     VLSTKKETMEKGMKVDEVGKIVRKHIPRRSILSIEYEEGLSSEETMELSRRQIANILE
                     DNISVFYGGVSGLVSIDKFLKEDKVIYDNSFVTVERDLFDIKSQKHITEISSGDFICM
                     TYKGPYKENYTAFKKLVDYVEYKRIPIENYIYEIPIIDPLSTNNEEELLTEIQIQVKK
                     REIDLRCLV"
     gene            complement(3641..6187)
                     /locus_tag="KR231_002864"
     CDS             complement(3641..6187)
                     /locus_tag="KR231_002864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HBH0005225.1"
                     /translation="MNIFNKVALQGLKKNRTRTLVTIIGVVLSAAMITAVTTFGVSLM
                     NYMTNGAIIKYGDWHVQFLDVDSSFVQEQRVNDEVANTATFENIGYATLEGNRNPDKP
                     YLFIAGFSKEAFDTLPITLISGRLPENSREILVSSKVATDGGVKFAVGDTISLDVGKR
                     MSENEKLGQSDPYTAGSEVFVPQDKKTYTVVGICRKPVFEESSAPGYTLITKEDKQVK
                     TDSLSLFVTLKNPHQIRSYISSTKDHASIFNDNVLRFIGVSDNNLFNMFLYSVGGIVL
                     AIIMLGSIFLIYNSFNMSLNERTHQFGILSSVGATAKQLRNSVLFEGICIGAIGIPIG
                     VAIGIVSIGLVISVIAKNFANILYVNVPLTLTLSIPAIIVAAVVSMVTILISAYIPAR
                     KAANTPVMECIRQTNEVKIESKSVKTSKLTQRVYGLEGVLAMKNFKRNKKRYRSIVLS
                     LVLSIVLFISTSALVADLKQMSNQRSEVTDQDIIFSTQGMKDNEMLKLYDKLKTANGV
                     YEGLYQKLMTYSCVAKVSELTDDYLNYEGSHSMSEMLELPVDMQFLDDRTYLNIIKSL
                     GLPAEEYTGQNAKLIAVSMVTKDNNIIDIFNSSSMNVSLTPETNGKLEIPERQNVNIS
                     FVKVVPPDSPPGIRSSDVKKASFRVLAPYSAKDKFEIPGVSTGIESLSFQSKNPTQSV
                     AEMEQIIESEGVTNEYNLYNMYGMMDENRNYIFIANVFAYTFIIMISLISIANVFNTI
                     STNIKLRRRELAMLRSVGMSEHDFQKMMNFECAFYGMRALFFGLPIAVISSWLIHKVM
                     VTDDIDFVIPWFSIGISIFSVLFIVFITMLYTINKIKKENIIDALRDDMA"
     gene            complement(6187..6873)
                     /locus_tag="KR231_002865"
     CDS             complement(6187..6873)
                     /locus_tag="KR231_002865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH0005226.1"
                     /translation="MAFLKIEDLCKVYGKNENKVTALDHVSLTIEKGEFTAIIGSSGS
                     GKSTLLHSIAGVDVPTSGKIYLEGQDVYGQSNEKLAIFRRRQVGLIYQFHNLIPTLNV
                     VENITLPILMDKRKVNQERLNDLLELLGLKERKTHLPNQLSGGQQQRVAIGRALMNAP
                     AVMLADEPTGSLDSKNGQEIIQLLKESHSKYHQTLIIVTHDENIALQADRIICISDGK
                     VVRDERKVNR"
     gene            complement(6956..7945)
                     /locus_tag="KR231_002866"
     CDS             complement(6956..7945)
                     /locus_tag="KR231_002866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBH0005227.1"
                     /translation="MFRNREFRKFAILFLLITILTVALGFAISIMTGILSIVSATTFG
                     IAFFVFTKNRYKSIAQISEQINLVLHNANHLYIAESDEGELSILQSEITKMTLRIREQ
                     NYALKKEKEHLADSLADIAHQLRTPLTSVTLILSLLENTSDEDERKELIRETEELLIR
                     MDWLITSLLKLSRLDAGIVVFQKEQIDVNNLISSALHQLLIPMELHNITLHIDIPKGV
                     RILGDLNWLSEAIQNIFKNCMESVGDNGKIDIICEDNFLFTQLTIHDNGAGFKKEDLP
                     CLFNRFYRGKNSSTAGYGIGLALCKTIIMRQGGTITAQNHPQGGAIFVIRFPK"
     gene            complement(7932..8618)
                     /locus_tag="KR231_002867"
     CDS             complement(7932..8618)
                     /locus_tag="KR231_002867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBH0005228.1"
                     /translation="MKRIFLVEDDKAIAKNLILLLNSEGFIVTHVSTRSEALVEIAKN
                     KFDLALIDISLPDGNGFTICTEIKEKQDIPVIFLTASGDESSVVTGLNMGADDYITKP
                     FRPRELIARIRTALRKSGRFGSTFEICGLYVDTATGVVKKNGNEVFLSALEYRLLLVF
                     ISNPKSIITRVRLLDELWDAAGEFVNDNTLTVYIKRLREKIEDDPSSPQIILTVRGTG
                     YRLGGSYVSK"
     gene            complement(9118..12324)
                     /gene="carB"
                     /locus_tag="KR231_002868"
     CDS             complement(9118..12324)
                     /gene="carB"
                     /locus_tag="KR231_002868"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011862003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamoyl-phosphate synthase large subunit"
                     /protein_id="HBH0005229.1"
                     /translation="MPKLDSIKKTLVLGSGPIIIGQAAEFDYSGTQACQALKEEGIEV
                     VLVNSNPATIMTDKEIADKIYIEPLTIEFIEKIIEKEKPDSLLAGMGGQTGLNLAVEL
                     HDAGILDKYNVKVIGTSIESIKKGEDRDLFREVMKEINQPVIVSDIVTNLEAGLEFAN
                     KIGYPVVVRPAYTLGGTGGGIADTEEELREILSHGLQLSPVGQVLLEKSIKGWKEIEY
                     EVMRDGNGNCITVCNMENVDPVGVHTGDSIVVAPSQTLSDEEYQLLRKASIDIINAIE
                     VQGGCNVQIALNPHSLEYAIIEINPRVSRSSALASKATGYPIAKVAAKIALGYTLDEI
                     ENAVTKKTYACFEPTLDYVVVKIPKWPFDKFRHANRKLGTKMMATGEIMSIGSNFEAA
                     ILKGIRSLETGKYSLVHAPSEGRTLEELKARVVVPDDERLFDLAEMIRRGYKVEMISE
                     ITGVDKWFINKFKWIVEQEEKLKVLKIEDLDKEYLHELKKKGFSDKGISDLMKISPEK
                     LYELRSLYNIQPVYKMVDTCGGEFEALSPYYYSTYEQYDEVVVSDKRKVVVLGSGPIR
                     IGQGIEFDYCSVHCVKSLRKMGIETIIVNNNPETVSTDFDTSDKLYFEPLTEEEVLNI
                     IEKEKPEGVILQFGGQTAIKLAKFLHEKNIPILGTDFRDIDAAEDREKFDDLLERLDI
                     NRPKGKGVWTTNEGVEIAKELGYPVLVRPSYVLGGQGMEITYNEEKLIQYLDDAFDRD
                     HKNPVLIDKYLTGREIEVDAICDKEDILIPGIMEHLERAGVHSGDSTTMYPSQNISDE
                     IKEKIVEYTKKIALDLNVLGMVNIQFIEFQNELYIIEVNPRASRTVPYISKVSGVPIV
                     DLATKCMLGAKLKDLGYSTGVYKEPKLVSVKVPVFSMSKLSKVEVSLGPEMKSTGEVL
                     GVGENLEEALYKGFLAAGRHMSDERGVVLATVNNHDKDEFIEIAKDMKELGYTFVATE
                     GTAKSLRENGIEADIVNRIEEPRPNILDAIRNKQVDIVINTPTKGNDSTRDGFKMRRT
                     AIEFSTEIMTSLDTLKALVEVKKKHLNKDKLKVYNIAE"
     gene            complement(12517..13566)
                     /gene="carA"
                     /locus_tag="KR231_002869"
     CDS             complement(12517..13566)
                     /gene="carA"
                     /locus_tag="KR231_002869"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002845470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing carbamoyl-phosphate
                     synthase small subunit"
                     /protein_id="HBH0005230.1"
                     /translation="MKARLILEDGTVFIGKAFGYLEESVGEVVFNTSMIGYGEVLTDP
                     SYYGQIVTMTYPLVGNYGINLSSAESEKVQVKGFIVREKSDSPSNFRCEIDIDQYLKQ
                     NKVIGLEGIDTRALTKILRNNGTMKGIITLEDSKLEDVKHKLDKFSNTEAVRTVTRKE
                     VEHIKGNGPKVAVMDFGVKRNILRSFIARGCDITIFPATTSPEDVLSINPDLIFLSNG
                     PGDPEDLEDVIENIKALIGKKPIVGICLGHQLLALALGGKTAKLKFGHRGGNHPVKDL
                     EEGKVFITSQNHGYYVSEVPEQMKVTHINLNDNTVEGMRHEKLDVYSVQYHPEACPGP
                     KDNDYIFDKFLELVK"
     gene            complement(13823..17029)
                     /gene="carB"
                     /locus_tag="KR231_002870"
     CDS             complement(13823..17029)
                     /gene="carB"
                     /locus_tag="KR231_002870"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011862003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamoyl-phosphate synthase large subunit"
                     /protein_id="HBH0005231.1"
                     /translation="MPKLDSIKKTLVLGSGPIIIGQAAEFDYSGTQACQSLKEEGIEV
                     VLINSNPATIMTDKEVADKIYIEPLTIEFIEKIIEKERPDSLLAGMGGQTGLNLAVEL
                     YEKGILDKYGVKIIGTSVESIKKGEDRDIFREVMKEINQPVIVSDIVTDLQAGLDYAL
                     TIGYPVVVRPAYTLGGTGGGIADNEEELREILSHGLQLSPVGQVLIEKSIKGWKEIEY
                     EVIRDSKGNCIVVCNMENIDPVGVHTGDSIVVAPTQTLSNKECAMLKKASLDILNAVE
                     VQGGCNVQFALNPHSFEYAVIEINPRVSRSSALASKATGYPIAKVSSKIALGYTLDEI
                     ENAVTKKTYACFEPTIDYVVAKIPKWPFDKFKKANRKLGTKMMATGEIMSIGSNFEAA
                     ILKGIRSLETGKYSLVHTPSEERSIEELKKRVVVPDDERLFDLAEMIRRGYKVEMIEQ
                     ITGIDKWFINKFKWIVEQEEKLKVMKIEDLTKDYLLELKKKGFSDKGISDLMKISPEK
                     LYELRSLYNIKPAYKMVDTCAGEIDAISPYYYSTYEQYDEVVVSDKKKVIVLGSGPIR
                     IGQGIEFDYCSVHCVKSLRKMDIETIIINNNPETVSTDFDTSDKLYFEPLTEEEVLSI
                     IEKEKPEGVILQFGGQTAIKLAKFLHEKNIPILGTDFDDIDAAEDREKFDDLLERLDI
                     NRPKGKGVWSLNEGIEVANELGYPVLVRPSYVLGGQGMEITYNEEKLSQYLQDAFDRD
                     HKNPVLIDKYLTGREIEVDAICDKEDILIPGIMEHLERAGVHSGDSTTMYPSQNISDE
                     IKEKIVEYTKKIALDLNVLGMVNIQFIEFQNELYIIEVNPRASRTVPYISKVSGVPIV
                     DLATKCMLGAKLKDLGYGTGVYKEPKLVSVKVPVFSMSKLSKVEVSLGPEMKSTGEVL
                     GVGENLEEALYKGFLAAGRHMSDERGVVLATVNNHDKDEFIEIAKDMKELGYTFVATE
                     GTANSLRENGIEADIVNRVEESRPNILDAIRNKQVDIVINTPTKGNDSTRDGFKIRRT
                     AIEFSTEIMTSLDTLKALVEVKKKHLNKDELKVYNIAE"
     gene            complement(17082..18125)
                     /gene="carA"
                     /locus_tag="KR231_002871"
     CDS             complement(17082..18125)
                     /gene="carA"
                     /locus_tag="KR231_002871"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011862004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing carbamoyl-phosphate
                     synthase small subunit"
                     /protein_id="HBH0005232.1"
                     /translation="MKGKLILEDGTVFEGKAFGYLKEAIGEVVFNTSMAGYGELLTDA
                     TYYGQIVTMTYPLIGNYGINLEDVESNKVQVKGLIVREKSDNPNNFRCEMDIDTYLKQ
                     NKVIGLEGIDTRALTKIIRNNGTKRGIITLENVSLQDVQSKLEEHCNKDSVKNVTRKE
                     IENIKGTGAKVVVIDFGVKNSVLESLKACNCDITIVPAMTTVEEILNINPDLILLSNG
                     PGNPEDINDIVENIKKLIGKKPLTGIGLGHQILALALGGKTSKLVFGHRGGNHPVKCL
                     ETGKVFITSQNHGYNVSEMPENTEVTHINLNDNTIEGMRHKELPIYSVQYIPEYTTKE
                     DLDCIFNKFLALI"
     gene            complement(18151..18867)
                     /gene="pyrF"
                     /locus_tag="KR231_002872"
     CDS             complement(18151..18867)
                     /gene="pyrF"
                     /locus_tag="KR231_002872"
                     /EC_number="4.1.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="orotidine-5'-phosphate decarboxylase"
                     /protein_id="HBH0005233.1"
                     /translation="MINGKEKLIVAIDTDEFDKAKELIDRLEDSVDIFKVGLEQYVAT
                     KGKTIDYLKEKGKKIFLDLKFHDIPNTMKSAVKAAVRDNVWLMTIHVSDMEGMRQCAL
                     IAREEAERLNIEKPLVVGVTVLTSLSNQDLQDIGCNMTTEELAIKRAKLAKESGIDGV
                     VCSAQEVDKIVEACGTDFITVCPGIRPKSAEVGDQKRVVTPSDAIKKGAHYLVVGRPI
                     TKAENPRESAINIVREIENA"
     gene            complement(19243..19878)
                     /locus_tag="KR231_002873"
     CDS             complement(19243..19878)
                     /locus_tag="KR231_002873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1847 domain-containing protein"
                     /protein_id="HBH0005234.1"
                     /translation="MYKCGKCNLRGCSNGNMDKLMKICPTREIELQQKAKQLYEEEEN
                     RKIAYNAGLVEAEGYCQYTRLKEIIEFAKKCGYKKIGIAFCIGLKREMQTVQKIFEHH
                     GFEVFSVICKNGAMPKSTIGLEASQTISKCSDEVMCNPIGQALFLNEAKVDLNVILGL
                     CVGHDTLAMKYMEAPITTLVVKDRVTGHNPVAAIYNAESYFEKKLFDKDEE"
     gene            complement(19902..20816)
                     /locus_tag="KR231_002874"
     CDS             complement(19902..20816)
                     /locus_tag="KR231_002874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0005235.1"
                     /translation="MELYEAIFYRKSVRNFSSKKIKKPLMEEIKRSCKNLEYLNEDLN
                     IKAHVVDRGHIIHFLMGKECKVKAPHYIVVTSDKGEDYLQNIGFATEGVVLRLTTLGI
                     ATCWLEGNLKREDILEFVDIGNKNFEEDEEDDLDYLAGIKTEEDDENKIENPYIIIAF
                     GYPAKNEELFRTRYARPDRKPVKDMINKINRNRKWKDILELTRRAPSVKNSQPWYFHK
                     DERGLHLFEKRPKKHCEDMNKVSLGVALRHFDIACIKNKIDVSYEKLPIRNKIGKSYF
                     ITVVEHVKPEEETQEENVTLEKEESQDE"
BASE COUNT         6651 a         3905 c         2600 g         7925 t
ORIGIN      
        1 acaaaacaat cattctattt taacatttat caatatgtct aaatttatat aattaacaca
       61 tacgaatagt attgtttaaa tcacattatt taagatagat aaatcttaac cctactccag
      121 cataaatact aaaatagggc ttagaattat ctatattttt atcccataaa atgcttagct
      181 cttcctcttg attgaacata tatatctggg gaaatacaat agaagcgtaa atttataaaa
      241 tttccaaagt cagaaaactt cagttcaaac ttaggtatac caaaactttc aggtgctatt
      301 tcgtcaacgc caaaatagat gataattcca ttatctgtaa gataaaatgc ttggtcttca
      361 ggtataacta actcaacatt agaataatac atttctctat tttcatttat ttgagattta
      421 atgtaatcag taattatatt aatataatca actccatctc taaaaatgtc attaagtaaa
      481 agttcttttc cagttgtcaa atctatattg taattattca atgtattgta tttaggccca
      541 tagttattag caaaccccat aaggtttaat atcatactca gtacataatt tttattaaaa
      601 gtaactgcgt aactggtaga tacccaatag ctttgttttg gaagtgaatt ttgagaagtt
      661 gcgttattat attctcgttc ttcttcctgt aagccatttt taaaattatt tacagtcatt
      721 cttacagcat tgtttatgtt atttaaaata actgggttta catacgtgga ttgatttcta
      781 atattgtata taacaggata ctttacatca tatgaaaaat acttacttct ttcaaaatct
      841 tcattaaatt gtacatataa tatattatat gtacaggtat ttgtagattg ataattttcc
      901 attaaaatcc tccccctttt ataaaaaaat cagatacaat ataatatgct taaaacagta
      961 ataatgttaa tggtaaatgt aaagaataga aagtatctaa aacagcaaaa aatgactaat
     1021 tttgtggtat aatacatagg attgagagtt attttatagg aggaaaaata tgttattatt
     1081 agcagataaa tggaaagatt atgaacttat agatatggga aatggagaaa aattagaacg
     1141 ttggggaagt tatgtactta gaagaccaga cccacaggtt gtatggccaa tggaatctga
     1201 atgggcttta tggaaaaacc ctcatggaca ttatcacaga agcaataaag gtggaggtca
     1261 atgggaacac aaaaaaagat atccagaaca atggactata aattataaaa acttaaagtt
     1321 tcacattaaa ccaactggct ttaaacatac tggattattc ccagagcaag cagctaactg
     1381 ggattggatg atagagaaaa taaagaaagc taacagacct ataaaagtgt tgaatctttt
     1441 tgcatataca ggtggagcta ctgtagcatg tgcatctgct ggtgcagaag tatgtcatgt
     1501 tgatgctgca aaaggtatgg ttaattgggc aaaagaaaat atagaattat caggtcttaa
     1561 aaatcaaaca gtaagattta tagtggatga tgttgtaaag tttgttgaaa gagaaataag
     1621 aagaggtaaa aaatatgatg caataataat ggaccctcct tcttatggaa gaggtcctaa
     1681 aggagaagta tggcaaatag aagaaaagtt atacagtttt gtagatttat gtatgggagt
     1741 tttatcagat aaccctttat ttttcttaat taattcttat acaacaggat tttctccaat
     1801 agttcttgaa aatgtattgt ctacaacaat aggtaaaaag acaaatacag gagatatata
     1861 cggtggggaa ttaggaatac cagcttccag agatggtaag atacttcctt gtggtatatt
     1921 tggaagatgg gagaaaaaat aatgataaaa gtcatatatg aagataacca tttattagtt
     1981 gtagaaaaac cagttaacat attgtctcaa ggagataata ctaatgataa agatatggta
     2041 aatcttttaa aagactatat taaaaaaaag tataacaaac ctggaaatgt atatattggt
     2101 ttaatacata gattggatag accagtaggt ggagttatgg tgtttgcaaa aacatcaaaa
     2161 gcagcatcta gattgtctga gcaggtaaga agtaagactt tcaaaaaaac ttatctagct
     2221 gttgttcatg gcaagataaa atctaactca gatatactaa aagatttttt atataaaaat
     2281 aaaaaaacta atatggtaac tgtagtgaaa aaaagccata aagatgccaa agaagctgaa
     2341 cttaactata atgtattaga ttttaaagaa aatctaagtt tagttcaagt taatttaaag
     2401 actggtcgtt ctcatcaaat aagagttcaa tttgcaagca gaaaacatcc attatacgga
     2461 gaccaaagat atggcaaaga aataaataag attggacaac aaatatctct ttggtccaat
     2521 aagatagaaa tttgccatcc tactacaaaa gaaaaaatgg aatttacatg tcatccacct
     2581 gacaaatatc catggaatat attttaaatc tcaaatgagg tgattatatg agtaaaaaat
     2641 tttcaatagg agaaatgtct aaacttcata aaataagcat acagacacta aggtactatg
     2701 accaaataga tttatttaaa cctgttcatg ttgaccaaga aagcaattac agatattact
     2761 caattgacca attttcacaa ttagatatta taaaatattt aaaatattta ggtatgcctt
     2821 taaaagaaat taagtcaaag cttgatgaaa ataatgaaga aattctaaaa ttactaacaa
     2881 ataaaattaa tatagtggat gaaaaaatta aagaattaga gcttataaag aaggtactaa
     2941 gcacaaagaa agaaactatg gaaaaaggta tgaaagtaga tgaagttggt aaaatagtga
     3001 gaaaacatat tccacgaaga agtatcttat ctatagagta tgaagaagga ttaagtagtg
     3061 aagaaactat ggaactttcc agaagacaaa tagcaaatat attagaagat aatatatctg
     3121 tgttctatgg tggagtaagt ggacttgtat ctatagataa atttttaaaa gaagataaag
     3181 ttatttatga caatagtttt gttactgttg aaagagactt atttgatata aaatcacaaa
     3241 aacatataac agaaatttca tctggtgatt ttatttgtat gacatataaa gggccttaca
     3301 aagaaaatta taccgctttt aagaaactgg ttgattatgt tgaatataaa agaataccta
     3361 ttgaaaatta tatatatgaa atacctataa tagaccctct gtctacaaac aacgaagagg
     3421 aacttctaac agaaattcaa atacaagtta aaaagagaga aattgactta agatgtctag
     3481 tgtagtaatc tagtttactt acacatctta atatagttgt ctattatcaa catatgattt
     3541 ttctagatag tgattcctaa cagtgagatt ttcaaaaaat aggaggaaat atggctaatg
     3601 ctaattccct cctattttta attaagccat atcattttaa ttaagccatg tcatcacgaa
     3661 gtgcatcaat aatattttct ttttttatct tattaatagt atacaacatt gtaataaata
     3721 ctataaataa aacactaaat atactaattc caatactaaa ccatggaatc acaaaatcaa
     3781 tatcatctgt aaccattact ttatgaatta gccatgaaga aattactgct ataggaagtc
     3841 caaagaacaa tgctctcatg ccataaaagg cacactcaaa attcatcatc ttttggaaat
     3901 catgctcaga cattcctaca gagcgaagca tggcaagttc tctacgacgt aacttaatat
     3961 tagttgaaat tgtattaaac acattggcaa tcgaaatcag agaaatcata attatgaaag
     4021 tataagcaaa aacattggca ataaaaatgt aattacggtt ctcatccatc attccataca
     4081 tattgtacag attgtactca ttcgtaactc cctcactctc aataatttgc tccatttctg
     4141 caactgactg agtaggattt ttcgattgaa agcttaaact ttcaattcct gtagaaacac
     4201 caggaatctc aaacttatct ttggctgaat aaggagccaa tactctgaag cttgctttct
     4261 tcacatctga acttctgatt cctggaggag aatcaggtgg cactactttg acaaatgaaa
     4321 tattcacatt ttgtctctca ggtatctcca acttgccatt agtttcagga gtgaggctaa
     4381 cattcataga agaactgttg aaaatatcaa taatattatt atcctttgtt accatagaaa
     4441 cagcaatcag ttttgcattt tgtccagtat attcttctgc tggtaatcca agacttttaa
     4501 taatattcag ataagttcta tcatcaagaa attgcatatc tactggtaat tcaagcattt
     4561 cactcataga atgtgaaccc tcatagttca aataatcgtc tgtaagctca cttactttgg
     4621 caacacatga ataggtcata agtttctgat acaaaccttc gtaaacacca tttgcagttt
     4681 ttagcttatc gtaaagcttc aacatttcgt tgtctttcat accttgtgta gaaaaaataa
     4741 tatcctggtc agtaacctct gacctctgat ttgacatctg ttttaggtct gctactaaag
     4801 cacttgtaga tataaataga actatgctta aaacaagcga caatacaata cttcgataac
     4861 gtttcttgtt tcttttaaag tttttcatag caagaactcc ctcaagacca taaactcgct
     4921 gtgttagttt tgatgtcttc acagatttag attcaatttt tacctcattt gtctgacgaa
     4981 tacactccat cactggtgtg ttggcagcct ttcttgctgg tatgtaagca gaaattaaga
     5041 ttgtaaccat acttaccact gctgcaacga tgattgcagg gatagacaat gttaatgtca
     5101 acggaacgtt tacatagaga atatttgcaa agtttttagc tatgacagaa atcacaagtc
     5161 caatactgac tataccgatt gcaacaccaa ttggtatacc aatcgcacca atgcaaattc
     5221 cttcaaatag caccgaattt cgtaactgtt ttgctgtagc tccaacagat gaaagtattc
     5281 caaattgatg tgttcgctcg ttcaatgaca tgttaaatga attatatatt agaaaaattg
     5341 agcctagcat gattatggca agcacaatgc caccaaccga gtacaaaaac atattgaaca
     5401 aattgttatc agaaacacct atgaagcgca acacattgtc attgaaaatg gaagcatggt
     5461 ctttagtgct acttatgtaa gagcgaatct gatgtggatt tttcaatgtg acaaaaaggc
     5521 taagactgtc agtcttgact tgtttatctt ctttggttat caaggtatat cctggtgcag
     5581 aagattcttc aaatacgggc tttctacaga tacccacaac tgtataagtt ttcttatcct
     5641 gtggcacaaa aacttcactc ccagcagtgt atgggtcact ctgaccaagc ttttcatttt
     5701 cactcattcg tttccctaca tccaaagaaa tagtatcacc tactgcaaat ttgacaccac
     5761 catctgtcgc aactttactt gaaacaagaa tctctctact attttcaggt aatcttccag
     5821 aaattaaagt tataggcaaa gtatcaaaag cttctttgct aaatccagca ataaaaagat
     5881 atggtttatc tggatttctg ttaccttcaa gtgttgcata gccaatattt tcaaatgttg
     5941 cagtatttgc aacttcatca ttgactcttt gttcctgtac aaaagaagaa tccacatcca
     6001 aaaactggac atgccaatca ccatatttta taatagctcc atttgtcata tagttcatca
     6061 aagaaactcc aaaggtagta actgctgtaa tcatagcagc tgacagaaca actcctataa
     6121 ttgttacaag agttcgagtg cgattctttt tcaatccttg cagagcaact ttgttaaaaa
     6181 tgttcattaa cgattcacct tcctctcatc acgcactact tttccatctg aaatacagat
     6241 aattctatct gcctgtaaag caatgttttc atcatgtgtg acaataatga gagtttggtg
     6301 atatttacta tggctctctt tcagtaactg gataatctct tgtccatttt tactgtctaa
     6361 gctacctgta ggctcatcag caagcataac tgctggtgca ttcatcaatg cacgaccaat
     6421 ggcaacacgt tgctgttggc caccagaaag ttgatttggt aaatgtgttt ttcgttcttt
     6481 taaaccaagc aattctaaca agtcatttaa ccgttcttga ttgaccttac gcttatccat
     6541 aagtataggc aatgtgatat tttctactac atttaatgtg ggtatcagat tgtgaaactg
     6601 ataaatcaat ccaacttgtc gcctacgaaa aatagcaagt ttttcattgc tttggccata
     6661 tacatcttgc ccctccagat atatctttcc acttgttggt acgtctactc ctgcaatgga
     6721 atgtagtagt gtagatttac cagaaccaga agaaccaatg attgcagtaa actctccttt
     6781 ttcaatagta agtgagacat ggtcaagtgc agtaacctta ttttcattct taccataaac
     6841 cttacataaa tcttcaatct ttaaaaacgc cattatataa gtctcctttc atattttata
     6901 aatatatcat aggactttca acttacattt aagtgacatt taaatgagag attcgtcact
     6961 ttggaaaacg aataacaaat attgcaccac cttgtgggtg attttgtgca gtaattgttc
     7021 ctccttgtct cataataatc gtcttacaaa gtgccaatcc tattccataa ccggctgtgc
     7081 ttgaattttt cccacgataa aatctgttaa atagacatgg taaatcttct tttttaaagc
     7141 ctgctccgtt gtcatgaata gtaagttgag taaacaaaaa gttgtcctca caaatgatat
     7201 caatttttcc attatcaccc acactctcca tgcagttttt aaatatattt tgaattgctt
     7261 ctgaaagcca atttaaatca cccaaaatcc ttactccttt tggtatatca atatgtaaag
     7321 tgatattgtg cagttccatg ggaatcaaaa gttgatgaag tgcagaacta atcaaattat
     7381 tcacatcaat ttgttctttt tgaaagacta caatacctgc atctaaacgt gataatttta
     7441 aaagggaagt aatcagccag tccattcgta taagtaattc ctctgtttct cgtatcaact
     7501 cttttctctc atcttcatca gaagtattct ctaacagtga caaaataaga gttactgatg
     7561 taagaggagt gcgaagctgg tgggctatgt cagctagtga gtcagcaagg tgttcttttt
     7621 cttttttcaa tgcgtaattt tgctctctaa tacgtaacgt cattttagtt atttcacttt
     7681 gcagaataga aagttcaccc tcatctgatt cagcaatata cagatggtta gcattatgaa
     7741 gcacaagatt aatttgttct gaaatctgtg caatactttt gtatcgattt ttagtaaaca
     7801 caaaaaatgc tattccaaag gtagtggcag aaacaataga aagtattcca gtcataatac
     7861 tgattgcaaa tcccagggct acagtgagaa tagtaattaa taagaataaa atagcaaatt
     7921 ttcgaaactc tctatttcga aacataactt ccccccaatc tataccctgt cccacgaaca
     7981 gtcaaaatta tttgtggact tgaagggtca tcttctatct tctctcgcaa gcgtttgatg
     8041 tacacagtca atgtgttgtc attaacaaac tcacctgccg catcccacaa ttcatcaagt
     8101 aatcttaccc tcgtaataat acttttagga ttgctaataa acaccaataa caaacggtat
     8161 tctaaagctg aaagaaaaac ctcattgcca ttctttttca caacaccggt tgccgtatct
     8221 acataaagcc cacaaatttc aaaagttgac ccaaaacgcc cactttttcg tagtgctgtt
     8281 ctaattcgcg caatcagttc acgtggacga aaaggtttag taatataatc atctgcaccc
     8341 atattcagtc cagtaacaac acttgattca tcaccggaag ctgtcaaaaa gataacagga
     8401 atgtcttgct tttctttgat ttctgtgcaa atcgtaaacc catttccatc aggtaaagaa
     8461 atatcaataa gtgccaaatc aaatttattc ttagcaatct ctacaagtgc ttcacttctt
     8521 gtggatacat gggttactat aaatccttct gaattaagca aaagaataag atttttggca
     8581 attgctttat catcctcaac taaaaatatc cgtttcattt actttcatcc tcctttattt
     8641 tattagtttt atatattcca gcagagcaat agtacactac tattttactt atcattacac
     8701 aattttcagt agtttctttt gttcttatat aatccatgca taatacctcc attgatttat
     8761 tatatttctt ataacataaa tacacaagat aagacaaaaa acataatgta agtgcaagtt
     8821 ttttaactca ctaacttata aacatacact cctactaaca ctactttctt gatgacacat
     8881 cttacaagct tatattcata catcaatgaa aaattaaatt tatccattta ttaaaataaa
     8941 aggcaatagc ttctatagct aatgcccttt atcttaaaat gatttaaata ctatacaatt
     9001 tttataaatg gctataaata aactcgtata gaatataaaa tttatctaca gtcttttgtt
     9061 atacaaaatt tataacctct tatagaacaa atttaccact ttgcaaactt atcactttta
     9121 ctcagctata ttataaactt ttaatttatc tttgtttaaa tgtttcttct taacttctac
     9181 taaagctttt agcgtatcca aagatgtcat tatttcagta gaaaattcaa tggctgttct
     9241 tctcatctta aatccatctc ttgtagagtc atttccttta gttggtgtat ttattactat
     9301 atcaacttgt ttatttctta tagcatctaa tatgtttggt ctaggctctt caattctatt
     9361 tactatatca gcctctattc cattttctct taaactcttc gctgttcctt ctgtagcaac
     9421 aaaagtatat cctaattctt tcatatcttt tgctatctct ataaactcat ctttatcatg
     9481 attatttaca gtagcaagta ctactcctct ttcatcagac atatgtctac ctgctgccaa
     9541 gaacccttta tataaggctt cttctaaatt ttctcctaca cctagaactt ctcctgtaga
     9601 cttcatttca ggtcctagac ttacttcaac tttagataat ttagacattg agaatactgg
     9661 tacttttact gatactaatt ttggctcttt gtaaactcct gtactatatc ctaaatcctt
     9721 taatttagct cctaacatac acttagtagc caagtcaact attggtactc cacttacttt
     9781 acttatatat ggaactgttc tactagctct agggttaacc tcaattatat ataattcatt
     9841 ttgaaattct ataaattgta tattaaccat accaagcaca ttaaggtcta aagctatttt
     9901 tttagtgtat tctactattt tttcttttat ttcatcagat atattttgac ttggatacat
     9961 tgttgtacta tctccagagt gaactccagc tctttctaaa tgctccatta taccaggtat
    10021 caatatatct tctttatcac atatagcatc tacttctatt tctctaccag ttagatattt
    10081 atctataagt actggatttt tatggtctct atcaaatgca tcatccaaat actgaattag
    10141 tttttcttcg ttataagtta tttccatacc ttgaccacca agtacataag atggtctaac
    10201 taatactgga taacctaact ccttagcaat ttcaacacct tcattagttg tccatacacc
    10261 ttttcctttt ggtctattta tatctagtct ctctagtaaa tcatcaaatt tttctctatc
    10321 ttctgctgca tctatatctc taaagtctgt tcccagtata ggtatatttt tttcatgtaa
    10381 aaacttagcc aattttatag ctgtttgtcc accaaactgt agtattacac cttctggttt
    10441 ttctttttct attatattta aaacttcttc ttctgttaat ggttcaaaat acaacttatc
    10501 agatgtatca aaatccgtac ttacagtttc agggttattg tttacaatta tagtttctat
    10561 tcccattttt cttaaagatt ttacacagtg aactgaacaa tagtcaaatt ctattccttg
    10621 acctattctt attggaccag aacccaatac tacaactttt ctcttatcac taactactac
    10681 ctcatcatat tgttcataag ttgaatagta ataaggtgat agagcttcaa attctcctcc
    10741 acatgtatca accattttat aaactggttg tatattatat aaacttctca attcatataa
    10801 tttttctggg cttatcttca ttaagtcaga tataccttta tcagaaaatc cctttttctt
    10861 taattcatgt aaatattctt tatctaagtc ttctattttt agaactttta acttttcttc
    10921 ttgttctact atccatttaa atttatttat aaaccactta tcaacaccag ttatttctga
    10981 tatcatttct actttatagc ctcttcttat catttcagct aagtcaaata gtctctcatc
    11041 atcaggtact actactctag cctttaattc ttctaatgtt ctaccttctg atggagcatg
    11101 aaccaatgaa tattttcctg tttcaagtga tcttatacct ttaagaatag cagcctcaaa
    11161 gttacttcct atactcatga tttcaccagt tgccatcatc ttagttccta attttctatt
    11221 ggcatgtcta aatttatcaa atggccactt tggtattttt actaccacat aatctaatgt
    11281 tggctcaaaa caagcataag tttttttagt tactgcattt tctatctcat ccaaagtata
    11341 acctaaagct atcttagctg ctacttttgc tattgggtat cctgtagctt ttgatgctag
    11401 ggctgatgac ctactaactc ttggatttat ttctattatc gcatattcta aactatgtgg
    11461 gtttaaagct atttgaacgt tacatccacc ttgaacctct attgcattta ttatgtctat
    11521 tgatgccttt ctaagtagtt gatactcttc atcacttaga gtttgacttg gagcaacaac
    11581 tatactgtct cccgtatgaa ctccaactgg gtctacattt tccatattac atacagttat
    11641 acagtttcca tttccatccc tcattacttc gtattctatt tctttccaac cttttatact
    11701 cttttcaaga agaacttgtc caacaggact tagctgtagt ccatgtgaaa gtatttctct
    11761 taattcttcc tcagtatcag ctatacctcc accagttcca cctagcgtat atgctggtct
    11821 tacaactact ggatatccta tcttattggc aaactcaaga cctgcttcta aatttgtaac
    11881 tatatcacta actattactg gttgatttat ttctttcatt acttctctaa ataaatctct
    11941 atcttcgccc ttttttatag attctataga tgttcctata acttttacat tatatttatc
    12001 taatatacca gcatcatgta attctacagc taagtttaat cctgtctgac cacccatacc
    12061 tgcaagtaaa ctatctggtt tttctttttc tattattttt tctataaatt ctattgttaa
    12121 tggttctata tatattttat ctgcaatttc tttatcagtc attatagtag ctgggttact
    12181 atttactaat acaacttcaa ttccctcttc ttttaatgct tggcaggcct gtgttcctga
    12241 atagtcaaac tctgcagctt gacctattat tattggccct gaccctaata ctaaagtttt
    12301 ctttatacta tctaatttag gcataactct ttctccttat ctaaacaatt ttcacagttc
    12361 ttatcttcat catctataca atcaacttta attactttat tttatcttaa attcaaattt
    12421 actcatcaat acatctattt aatacatcta tgttaattaa accaaacttt ttgatttaag
    12481 ttattcttgt tttttagtta gctattctaa tgttatttat tttactaatt ctaaaaattt
    12541 atcaaaaata tagtcattat cttttggtcc tgggcaagct tcaggatggt attgaacact
    12601 gtatacatct agtttctcat gtctcattcc ttcaacagta ttatcattta aatttatatg
    12661 tgtcactttc atttgttcag gaacttctga aacataataa ccatgatttt gagaagttat
    12721 aaatactttt ccttcttcta aatctttaac tggatgattt ccacctctat gcccaaattt
    12781 aagtttagca gtttttcctc caagagctaa agctaaaagt tgatgtccta agcatattcc
    12841 aactataggt tttttaccaa taagagcttt tatattttct ataacatctt ctaggtcttc
    12901 tgggtctcca ggtccatttg acaagaatat taagtcaggg tttatactca atacatcttc
    12961 tggagatgtt gtagctggaa atattgttat atcacatcca cgagctataa atgatcttaa
    13021 tatatttctt tttactccaa aatccataac agccactttt ggaccatttc cctttatatg
    13081 ctctacttct tttcttgtaa cagttctaac tgcttctgta tttgaaaact tatccaattt
    13141 atgtttaaca tcttctaatt tactgtcttc taatgtaatt atacctttca tggttccatt
    13201 atttctaagt atcttagtca aagctcttgt atctattcct tcaagtccga taactttatt
    13261 ttgctttaaa tattggtcta tatcaatttc acatctaaaa ttacttggag aatcactttt
    13321 ctcccttact atgaatccct ttacttgaac tttttcagac tctgctgatg ataaatttat
    13381 accataattt cctacaagag gataagtcat agtaactatt tgaccatagt aagaagggtc
    13441 tgttaaaact tcaccatatc ctatcattga agtattaaat actacttctc ctacactttc
    13501 ttctaaatat ccaaatgcct ttcctataaa aactgttcca tcttctaata ttaaccttgc
    13561 tttcatacta cagtacctcc tataattctc tttagacaaa ctaaagaaca ttaactaaat
    13621 ataagctttt aaatatctat atctattttt cacttttaca ttctagtttt atacttattt
    13681 acatttattt tttatctttt tctattatac tacaaatttc ttaaaaaaaa gaagttatct
    13741 caaaagtaaa aactcctaga aaaaataacc tctttttttt atttaataat taaattctta
    13801 aactatacaa tcaacttaat ttctattcag ctatattgta aacttttaac tcatctttat
    13861 ttaaatgttt cttcttaact tctactaaag cttttagtgt atccaaagat gtcattattt
    13921 cagtagaaaa ttcaatagct gttcttctta tcttaaatcc atctcttgta gagtcatttc
    13981 ctttagttgg tgtatttatt actatatcaa cttgtttatt tcttatagca tctaatatgt
    14041 ttggtctaga ttcttctact ctatttacta tatcagcctc tattccattt tctcttaagc
    14101 tattagctgt tccttctgta gcaacaaaag tatatcctaa ttctttcata tcttttgcta
    14161 tctctataaa ctcatcttta tcatgattat ttacagtagc aagtactact cctctttcat
    14221 cagacatatg tctacctgct gccaagaacc ctttatataa ggcttcttct aaattttctc
    14281 ctacacctag gacttctcct gtagacttca tttcaggtcc tagacttact tcaactttag
    14341 ataatttaga cattgagaat actggtactt ttactgatac taattttggc tctttgtaaa
    14401 ctcctgtacc atatcctaaa tcctttaatt tagctcctaa catacactta gtagccaagt
    14461 caactattgg tactccactt actttactta tatacggaac tgttctacta gctctagggt
    14521 taacctcaat tatatataat tcattttgaa attctataaa ctgtatatta accataccaa
    14581 gcacattaag gtctaaagct atttttttag tgtattctac tatcttttct tttatttcat
    14641 cagatatatt ttgacttgga tacattgttg tactatctcc agagtgaact ccagctcttt
    14701 ctaaatgttc cattatacca ggtatcaata tatcttcctt atcacatata gcatctactt
    14761 ctatttctct accagttaga tatttatcta taagtactgg atttttatgg tctctatcaa
    14821 atgcatcttg taggtattga gataattttt cttcgttata agttatttcc ataccttgac
    14881 caccaagtac ataagatggt ctaactaata ctggataacc taactcatta gcaacttcaa
    14941 taccttcgtt aagtgaccat acaccctttc cttttggtct atttatatct agtctctcta
    15001 gtaaatcatc aaatttttct ctatcttctg ctgcatctat atcatcaaaa tcagttccca
    15061 gtataggtat atttttttca tgtaaaaatt tagccaattt tatagctgtt tgtccaccaa
    15121 actgtagtat tacaccttct ggtttttctt tttctattat acttaaaact tcttcttctg
    15181 ttaatggttc aaaatacagc ttatctgatg tatcaaagtc tgtacttaca gtttcagggt
    15241 tattgtttat gattatagtt tctatgtcca tttttcttaa agattttaca cagtgaactg
    15301 aacaatagtc aaattctata ccttgaccta ttcttattgg accagaacct aatactatca
    15361 cctttttctt atcactaaca actacctcat catattgctc ataagttgaa taatagtaag
    15421 gagatatagc atctatctca cctgcacaag tatcaaccat tttatatgct ggtttgatat
    15481 tgtatagact tctcaattca tataattttt ctggacttat cttcattagg tcagatatac
    15541 ctttatcaga gaatcccttt ttctttaatt caagaagata gtctttagtt aaatcttcaa
    15601 ttttcataac ttttaatttt tcttcttgct ctactatcca tttaaattta tttataaacc
    15661 atttatctat acctgtaatt tgttctatca tttctacttt atagcctctt cttatcattt
    15721 cagctaaatc aaatagtctc tcatcatcag gtactacaac tcttttcttt aattcctcaa
    15781 tgcttctctc ctcagatggt gtgtgaacta atgaatattt tcctgtttca agtgatctta
    15841 tccctttaag aatagcagcc tcaaaattac ttcctatact cataatttca ccagttgcca
    15901 tcatcttagt tcctaatttt ctatttgctt ttttaaattt atcaaaaggc cattttggta
    15961 tttttgccac cacataatct atagttggtt caaaacaagc ataagttttt ttagttactg
    16021 cattttctat ctcatctaaa gtataaccta aagctatttt tgatgaaact ttagctattg
    16081 gatatcctgt agcttttgat gctaaagctg atgacctact aactcttgga tttatctcta
    16141 taactgcata ttcaaaacta tgtggattaa gtgcaaattg aacgttacaa ccaccttgaa
    16201 cttctactgc atttaatata tctaaagatg cttttttaag cattgcacat tctttgttac
    16261 ttaaagtttg agttggagca acaactatac tgtctcctgt atgaactccg actgggtcta
    16321 tattttccat gttacataca actatacaat ttccctttga atctcttatt acctcatatt
    16381 ctatttcttt ccaacctttt atactctttt caattaatac ttgtccaaca ggacttaatt
    16441 gtagaccatg tgaaagtatt tctcttaatt cttcctcatt atcagctata cccccaccag
    16501 ttccacctag tgtgtatgct ggtcttacaa ctactggata accaattgta agtgcataat
    16561 caagacctgc ttgtaaatct gtaactatat cactaactat tacaggctga tttatttctt
    16621 tcattacttc tctaaatata tctctatctt cacctttttt gatagattct actgaagtac
    16681 ctattatttt tactccatat ttatctagta tgcctttttc ataaagttca actgctaggt
    16741 ttagccctgt ttgtccaccc atacctgcaa gtaaactgtc tggtctttct ttttctatta
    16801 ttttttctat aaattctatt gttaatggtt ctatatatat tttatctgcc acttctttat
    16861 cagtcattat agtggctgga ttactattta ttaatacaac ttcaatccct tcctctttca
    16921 aagactggca agcttgtgtt cctgaatagt caaactctgc agcttgacct attattattg
    16981 gtcctgaccc taatactaaa gttttcttta tactatctaa tttaggcata aatttttctc
    17041 cttatctaaa tggtttttac tatctgtaaa taatactaaa tctatattaa tgctaagaat
    17101 ttattaaata tacaatctaa atcttctttt gttgtgtatt ctggaatgta ctgaacacta
    17161 tatattggta attccttatg tctcattcct tctatagtat tgtcatttaa atttatgtga
    17221 gttacttctg tattttctgg catttctgaa acattatatc catgattttg agaagttata
    17281 aatacctttc cagtttctaa acatttaact gggtgattac ctcctctatg tccaaataca
    17341 agctttgaag tctttcctcc taatgccaat gctaaaattt gatgtcctaa acctattcct
    17401 gtcaatggct ttttgcctat taattttttt atattttcaa ctatatcatt tatatcctct
    17461 ggatttcctg ggccattaga taataagatt aagtcaggat ttatatttaa aatttcttct
    17521 actgtagtca ttgctggtac tatagttata tcacagttac aagccttaag agactctagt
    17581 acactatttt taacaccaaa gtctataact acaactttag ctccagtacc ttttatattt
    17641 tcaatttctt ttcttgtaac attttttact gaatctttgt tacaatgctc ttctaattta
    17701 gactgaacat cttgtaatga tacattttct aaagttataa ttcctctctt agttccattg
    17761 tttctaataa ttttagttaa tgctcttgta tctattcctt caagtcctat taccttattt
    17821 tgctttagat atgtgtctat atccatttca catctaaaat tatttgggtt atcacttttt
    17881 tctcttacaa taagtccttt tacttgcacc ttatttgatt caacatcttc taaatttatt
    17941 ccatagtttc ctataagtgg ataagtcata gtaactattt gtccataata agttgcatct
    18001 gtcaatagtt ctccataccc agccattgaa gtattaaata caacttctcc aatagcttcc
    18061 tttagatatc caaatgcttt tccttcaaat actgttccat cttctaaaat taatttcccc
    18121 ttcatgtaag ctacctccca aatattttat ctaagcattt tctatttctc ttacaatatt
    18181 aatagctgat tctcttggat tttctgcttt tgttataggt cttccaacaa ctaaataatg
    18241 agcacctttt tttattgcat ctgatggagt tacaactctt ttttggtctc caacctctgc
    18301 tgatttaggt cttattcctg ggcaaactgt tataaaatca gttccacatg cttctactat
    18361 tttatctact tcttgcgctg aacaaacaac cccatctatt cctgattctt ttgccagttt
    18421 agctctcttt atagctaact cttctgttgt catattacat cctatgtcct gtaaatcttg
    18481 gttgcttaat gaagttaaaa ctgttactcc aactactaat ggcttttcta tatttaatct
    18541 ttctgcttct tccctagcaa ttagtgcaca ttgtctcatt ccttccatat ctgatacatg
    18601 tattgtcatt aaccaaacat tatctctcac tgcagctttc actgcacttt tcatagtatt
    18661 tggtatatca tggaatttaa ggtctaaaaa tattttttta cctttttctt taagataatc
    18721 tattgtttta ccttttgtgg caacgtattg ctctagccct accttaaata tgtctacact
    18781 atcttctaat ctgtctatta gttctttagc tttatcaaat tcgtcagtat caattgcaac
    18841 tatcaatttt tctttaccat ttatcatttt tacatctcct ttttaataaa gcctaaataa
    18901 tcataaaaaa atcctcacac caaaagaggc ataaggattt tatctataca taactctatt
    18961 cattagctat gagatatctt tcccagtctc tctggactag tttaaaagac tttattatat
    19021 ttaaattttt attttatact catcaaaaac ctctagaaga tttactagag gttatatact
    19081 aacattatct ataacccttt agtctctctg gactacttta aggaatttag ctgtaatatt
    19141 tttctttatt tatataactt tatgtatcta taggataatt taaagtttta tcttttttat
    19201 aattaaacca ctaattgctt tttatgtcaa taagtctttg aattattctt catctttatc
    19261 aaacaatttt ttctcaaaat atgattctgc attatatatt gcagcaactg gattatgccc
    19321 agttactcta tctttgacaa ctaaagttgt tataggagct tccatatatt tcatggctaa
    19381 agtatcgtga ccaacacata atccaagaat tacattaagg tcaaccttag cttcatttaa
    19441 aaataaagct tgtcctattg gattgcacat tacctcatct gaacactttg atattgtttg
    19501 agatgcttct agtccaattg tactcttagg cattgcccca tttttacata taacagaaaa
    19561 tacttcaaac ccatgatgtt caaatatttt ttgcactgtt tgcatttctc tttttagtcc
    19621 aatacaaaat gctatgccaa tctttttata accacacttt ttagcaaact ctataatctc
    19681 ttttagtcta gtatattgac aatacccctc tgcttcaact aatccagcat tataagctat
    19741 ttttctattc tcttcttctt cataaagttg ctttgctttt tgttgtagtt caatttctct
    19801 agttggacat atcttcatta atttatccat atttccatta gaacagcctc taagattaca
    19861 ttttccacac ttatacatat ccaatatccc cttccaaaat tttattcatc ttgcgattct
    19921 tctttttcta gagttacatt ttcttcttgg gtttcttctt ctggtttcac atgctcgact
    19981 acagttataa aatatgattt tcctatttta ttccttatag gaagtttttc atatgaaaca
    20041 tctattttat tttttataca agctatatca aaatgtctta aggctacacc taagctaacc
    20101 ttattcatat cttcacagtg tttcttaggt ctcttttcaa ataaatgaag acctcgttca
    20161 tccttatgga aataccacgg ttgagaattt tttacagatg gagctcttct tgtcaattct
    20221 aagatatctt tccactttct attcctattt atcttattta tcatatcttt tactggcttt
    20281 ctatcaggtc tagcatatct cgtcctaaac aactcttcat tttttgctgg atatccaaat
    20341 gctattatta tataaggatt ttctattttg ttttcatcat cttcttctgt ttttattcca
    20401 gctagataat ctaaatcatc ttcctcatct tcttcaaaat tcttattccc aatatctaca
    20461 aattccaaga tatcttctct ctttaagttt ccttccaacc agcaagtagc tattcccaat
    20521 gttgtaaggc gcaaaactac accttctgta gcaaatccta tattctgtaa atagtcctca
    20581 cctttgtctg atgtaactac tatataatga ggtgccttta ctttacattc cttacccatc
    20641 aaaaaatgta ttatatgacc tctatcaaca acatgtgctt taatatttaa atcttcattt
    20701 aagtattcta aatttttaca acttcttttt atttcttcca tcaatggctt ttttatcttc
    20761 ttactggaaa aatttcttac agattttcta taaaaaatgg cttcataaag ctccatttat
    20821 gccctcctaa ctgaaatctt ctgacgtata aactctataa atttatataa atactttata
    20881 ttttttatag ttttatttcc tttttcctcc tgccctattt tgaaattcat aagaatatct
    20941 actctagttt aatatagcat tcaaaaggct taaattctac cttatcaatg tctatacatt
    21001 agcataattt ttttatttga ttttctatgc taatttaaat aacaacacta gctattacct
    21061 ttttaattaa gctttgccag a
//
LOCUS       DAEPHU010000071        20970 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 01A10CD0081
            SAMN05941466-rid12468953.denovo.071, whole genome shotgun sequence.
ACCESSION   DAEPHU010000071 DAEPHU010000000
VERSION     DAEPHU010000071.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941466
            Sequence Read Archive: SRR6291087
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 20970)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20970)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068158.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 22:43:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,892
            CDSs (total)                      :: 3,805
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 87
            rRNAs                             :: 8, 1, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 55
            CDSs (without protein)            :: 55
            Pseudo Genes (ambiguous residues) :: 0 of 55
            Pseudo Genes (frameshifted)       :: 21 of 55
            Pseudo Genes (incomplete)         :: 28 of 55
            Pseudo Genes (internal stop)      :: 16 of 55
            Pseudo Genes (multiple problems)  :: 8 of 55
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20970
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941466-rid12468953.denovo.071"
                     /strain="01A10CD0081"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            <1..105
                     /locus_tag="KR231_002875"
     CDS             <1..105
                     /locus_tag="KR231_002875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018368130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase P60"
                     /protein_id="HBH0005236.1"
                     /translation="GNNQMYHAGDPIGYADLSSSYWQQHLIGAGRVKQ"
     gene            121..1032
                     /locus_tag="KR231_002876"
     CDS             121..1032
                     /locus_tag="KR231_002876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HBH0005237.1"
                     /translation="MFKKNKKQTETVKEPKEKKVRTVKVGTHKKTMIALWVVLIASVS
                     FGVYKNFTAIDQHTTHEKEIIELRLQDTNGIENFVKNFAKSYYTWSNSKEAIEARTQA
                     ISGYLTKELQDLNVDTIRTDIPTSSTVTDVIVWHIEQSGTDTFSATYEVDQQIKEGEQ
                     TSNVKATYTVKVHVDADGDMVIIQNPTLAPAIEKSDYEPKTPEADASVDADTVNDATA
                     FLETFFKLYPTATEKELAYYVSGNVIEPIGRDYLYSELVNPIFTKNGDNVKVKVAVKF
                     LDNQTKATQVSQYELVLHKDSNWKIVG"
     gene            complement(1079..1636)
                     /locus_tag="KR231_002877"
     CDS             complement(1079..1636)
                     /locus_tag="KR231_002877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005946872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBH0005238.1"
                     /translation="MKTTKEAVIKATSDLADEKGLNNVSLKAVAQKLNIRTPSLYNHI
                     ESLDNLLLEVAHNGMRDMNERMMKIAVGKIGKEAIKLVSIEYLNYMIEHPGVYETIQW
                     AVWHGTEETATIFNNYLSLLTTLIQSCSLNKDKTLEILNMLTGIIHGYTTLQLGNAFS
                     ASDKVRFELAEAIDTLLVGIFQKYK"
     gene            1814..2509
                     /locus_tag="KR231_002878"
     CDS             1814..2509
                     /locus_tag="KR231_002878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016179626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HBH0005239.1"
                     /translation="MCTRFVYNGIDKIVGFNFDIDLSVWDHTVITEENRFYIGIKMPD
                     GLYHSFHGINKNGNVGTLLYVHGNENARYIESEDCITISELTEKFIKAEISFDKALDI
                     VKKKKIIYAPDATMQAMLSDKKGRVLIIEPGIGYRYEQENFSLITNYSILKPDITKPY
                     IVSGDTRYEVAKELLAGYDKDFSVNDAFKVLKSVSQKDLWATRVSFVYSTEKNKVYYV
                     LNNDFSNVFEFQF"
     gene            2555..2779
                     /locus_tag="KR231_002879"
     CDS             2555..2779
                     /locus_tag="KR231_002879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008393106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0005240.1"
                     /translation="MIGLKKRDIKKALKAGAKAGGVSLADVRADIEATIDEAMNSTAP
                     EVQANFKKYFGNKRPTPEEYIYKITKKTKI"
     gene            complement(2825..4117)
                     /locus_tag="KR231_002880"
     CDS             complement(2825..4117)
                     /locus_tag="KR231_002880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBH0005241.1"
                     /translation="MLNNLYRKLHILFASSVMLIITLVISFVVANTVHTEKINESTLF
                     QRLTTLLIYQVESASSDMDKALKTYEESYHIFSLITDTRGNTIYQSDFPFPTSADNLL
                     HDVEKQISTQPLSQIENSTTSQGGFLEIRGTHHDTYFVIPATIRTANDTVYHATFLYQ
                     TASLTDILQKTLPIYLLIWFLACIVVIVLTRYLLKKSFAPTERILQSQKDFVATASHE
                     LKSPLAVMISNTDMLLDNVSLNEQAKQAVQTIDFECMRLSRLVKDMLLLASSDAKTWT
                     LHKSTINVDTLLITLYETYEPVCMKQNLELKLHLSEESYPAMFTDKDRLFQILCVFMD
                     NAIQHSKNNSLIEIEVIATEKNIAFSVVDHGQGISDEDKQYIFDRFYSGDKSHTNKSN
                     FGLGLSIAKELTQMLNGIIIINDTAGGGATFTVKFPLK"
     gene            complement(4111..4797)
                     /locus_tag="KR231_002881"
     CDS             complement(4111..4797)
                     /locus_tag="KR231_002881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005342376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBH0005242.1"
                     /translation="MKILLLEDDLELCKNIKISLEKENYMVDCCNDGETAMLYALNTD
                     YAYDLAIVDRMLPIIDGLTIIKSMRRKGISIPILIITAMSTLDNRVEGLDGGADDYLV
                     KPFHIKELLARVRALTRRPANIQLSSKLEYGDLTFDKDSRTLSTPVNSLLLTSKETEL
                     TFVFMQNPETLFSREQLILKIWGSSSEVETGNVDSYISFLRKRLKELKSSCKITTVYG
                     AGYKLEKETC"
     gene            4960..5457
                     /locus_tag="KR231_002882"
     CDS             4960..5457
                     /locus_tag="KR231_002882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chitinase"
                     /protein_id="HBH0005243.1"
                     /translation="MKKTNISKFVAVGLCICALTGCGASPDEKPDTSNPIVNSNTNEE
                     NANGSSENKGNDILESANLIGSVLEFTDNGCSVSQAKETEGGASLQIEASGLENKDNA
                     VSVTYNPDCEFFVATLNKQLGSVTNITTGSISDVKKQSNVYLYGEFSDTLHFNATKVV
                     IARWE"
     gene            5469..6692
                     /locus_tag="KR231_002883"
     CDS             5469..6692
                     /locus_tag="KR231_002883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBH0005244.1"
                     /translation="MKFYQLGFRYLQRKKGKTILLLIVLILVNSMILGTSMILRTTNE
                     SKQAMQEKTNSKIVAEITSKDSKITENEVNKIETLEDVSSINRIGRQEVFPNDFAPVT
                     LNTSTNEENLKIALLSYDDLEKDSPFSEMQYRLSSGDYIKHEKKGAVINANLANQNEL
                     KVGDTIELSTENGTKVSVQIIGIFMSAGNVEKDQPTETTAVNRIENQVFIDNSTYKEL
                     FKEAEFEKLCVYSKRPEKLDVLETSLQKIFGNDVELSTSDTLYQQMSAPLEQISKVAN
                     LMLVLTLVTGTVVVSLLLCMWMRTRQKEVAIFMSLGKTKSEIFLQTLLEAGSVFTLSV
                     LGATAIGKLFSGVLQNVITGSETVTENLKVVLQIQDIGMLFLLGGAVILVALCCSILP
                     ILRANPKDILAKMEG"
     gene            6696..8141
                     /locus_tag="KR231_002884"
     CDS             6696..8141
                     /locus_tag="KR231_002884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005342380.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBH0005245.1"
                     /translation="MNFFGLARRSVFRKPIKSILLLLIVFAISTLLLAGVASKNASIE
                     VQDKTRQAIGAGFLLERNAEYRTKRVREYSEKIGNDKEGSFGGYHQEKEIINGVETWS
                     GWTTNEFESLDIKDIEKLAKTKGIADYNITTATTPVNPVNFKRIEDKDVDQSVDEGGV
                     SLIGNKDMKLDRNVLSGNLHIKEGRMITPEDKDMCVISEELAKQNNLKIGDKISFNDY
                     HDTVNSKVSEAEIVGIYQVDQKMSPLMQGDTYRSENVIFTDLRFPEKAEGETSPLYER
                     AYFKVEDVEAYDEVKENLQKVDINWEQYDLIDNNGNSETMSSNFNDLAKVSEMMILVI
                     SVASFVILVLVFLFWLKNRVQEVGIFLSLGVPKFRIIGQIWSEAIMIAVLSLMLSFAV
                     APAVSKVTANYLVSQQVQQMQEEEKNNEGKVSTEYVAPKQDVQNISVEVTPEMYLLDG
                     VSVLVLITASVLVSGIVILKRNPKDILSEMS"
     gene            8155..8790
                     /locus_tag="KR231_002885"
     CDS             8155..8790
                     /locus_tag="KR231_002885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905051.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH0005246.1"
                     /translation="MLEVKNVSYAYKTKKDKTILNNVSATFEEGIFYTIVGPSGAGKT
                     TLLSLLAGLDTAVKGTVLCNGEDITKKGLNYHRKHNISLVFQNYNLIDYLTTVENVKL
                     GGSGNAEKLLEEVGIGKEYWQRNVLQLSGGQQQRVAIARALASDAHVLLADEPTGNLD
                     ETTADEIIALLKKTAHELGKCVVVVTHSKHLAEEADEILEIKNGAISFLSD"
     gene            9065..9505
                     /locus_tag="KR231_002886"
     CDS             9065..9505
                     /locus_tag="KR231_002886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0005247.1"
                     /translation="MKPSELQEKTCHQFDCAIKTVIRHRAIDFYRAIRRSEKKEMPFA
                     EIMDDLLNSIGTEDTYSTDYVAVFEVCGEKVSIEDEQLARALKAIEERKRNIVLQYFF
                     IGDTDTYIGKMLDCSRANVTKCRIQALDKLKQLIEEEKEKCQKS"
     gene            9490..9723
                     /locus_tag="KR231_002887"
     CDS             9490..9723
                     /locus_tag="KR231_002887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBH0005248.1"
                     /translation="MPKELTPTFTVISKACDGDETAISKILEFYDPYINRCCMRPFYD
                     DNNNLRLAVDLEMKGFIKEAIIRKILNFDIKRF"
     gene            10037..10240
                     /locus_tag="KR231_002888"
     CDS             10037..10240
                     /locus_tag="KR231_002888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002262306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excisionase"
                     /protein_id="HBH0005249.1"
                     /translation="MNNTDVPIWEKYTLTIEEASKYFRIGEKKLRKLAEENLDAGWVI
                     VNGNRIQIKRKQFEKIIDTLDEI"
     gene            10318..11508
                     /locus_tag="KR231_002889"
     CDS             10318..11508
                     /locus_tag="KR231_002889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009271880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HBH0005250.1"
                     /translation="MSNVKRKDSKNRNLRNGESQRKDGRYVYKYTDIYGKPQFIYSWK
                     LVPTDKTPAGKRDDISLREKEAQIKKDLNDGIDTVGGKMTVCQLYDKKNSQRKNIKRA
                     TEKGRQYLMNALKNDPLGMRAIDTVKQSDAKEWAIRMSEKGYAYKTIDNYKRSLKASF
                     YMAIQDDCIRKNPFEFKLSDVLEDDTEQKVILTPEQEGRLLAFMEKDKIYSKYYDEVV
                     LLLETGLRISEFCGLTTHIDMQNRILNIDHQLLKDSEMGYYIETPKTKNGKRELPLTE
                     RAYQAIQRILKNRGKAQPLIVGGYSNFLFLNREGLPKVAGNYEGMVRGLIKKYNKYHT
                     DKLPNITPHSFRHTYCTNMANRGMNPNTLQYLMGHANITMTLGYYAHGTFQSAKAELE
                     RLAC"
     gene            complement(11671..12759)
                     /locus_tag="KR231_002890"
     CDS             complement(11671..12759)
                     /locus_tag="KR231_002890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011010417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class I/II-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="HBH0005251.1"
                     /translation="MSTNHGANLYSLSSKYGFSKEEFMDFSSNINPFGTSSLAKQYIV
                     NNIDMVSMYPDPDYIDLKTSISNYCKCSIDNIVLGSGATELISSFIHTINPKQALLLS
                     PAYSEYEKELSKINCSIEKYFAKEEDNFHINLENLIKTINAKDYDLVVICNPSNPTGF
                     AFTKVEVREILKNTDSFLMIDETYVEFTDTDTYSCTQLVDDYSNLFVIRGTSKFFSTP
                     GIRLGYGLISNTNVKNEINKNLDLWNINIIASKMGEIMFSDLDFISNTISLMNTERDY
                     LLKELKNIKSLDIYNTKGNFILCKIKTKELTAKSLREQLLPQKIIIRDCCSFEGLDEY
                     FFRVCILKPNENKLLISSLKAIFILKTY"
     gene            12988..13515
                     /gene="hpt"
                     /locus_tag="KR231_002891"
     CDS             12988..13515
                     /gene="hpt"
                     /locus_tag="KR231_002891"
                     /EC_number="2.4.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypoxanthine phosphoribosyltransferase"
                     /protein_id="HBH0005252.1"
                     /translation="MYKVTGKMLTEEQIKEKVYELGKKIEEDFKGEDLLVVGILKGAS
                     VFVSDLIRCIDLDVNIDFMSVTSYGNSTESSGTVKILKDLDVDIEGKNVLIVEDIIDS
                     GLTLSNLVAALKTRNPKSLKLCTLLDKPQRRKANIPVDYVGFVIEDKFIVGYGIDYAE
                     KYRNLPYIGIVEDVE"
     gene            13604..14536
                     /locus_tag="KR231_002892"
     CDS             13604..14536
                     /locus_tag="KR231_002892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HBH0005253.1"
                     /translation="MDIQLNILLFFQNLRNPILNFIFLVFTISTEAPLLILITTIIYW
                     CINKKCGQKILFAIIGNFVVNLGIKEFVKAPRPIGIKGLESLRVSTAGGYSFPSAHTQ
                     TATTFWVSIMTIFKKRYLHLIGAVMVLGVGLSRLYLAVHWPIDVIAGWILGIFFTVVF
                     VKIFDYIDDNKNYILLVVLLIPFIIVAIFLNSPEYFEKFGIIVGFVFGYMVEDRFVKF
                     NTDNNNKKINFSNKNKGSKNIIFSRICRFLVGIVTIGMLYIGIKLFISMLIVTLNISD
                     STMSIIFMNFIKNTVVVFYGIAGAPALFKLLKLN"
     gene            14598..15824
                     /locus_tag="KR231_002893"
     CDS             14598..15824
                     /locus_tag="KR231_002893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HBH0005254.1"
                     /translation="MKKVVIIGGGPAGMIAASTACEKGYDVTLIEKNHKLGKKLAITG
                     KGRCNITNACEIEELIENVPTNGKFLYSAFYTFTNDDVISMFNNLGVKTKTERGKRVF
                     PESDKAFDIVNALERQLKSKKVNILLNSKVEKIISKNNKIEKVILNDKKEIKCDSVVV
                     ATGGLSYPLTGSTGDGYKFAISQGHTIIDTKPSLIGIEVQESFTKDLEKLSLRNVEIR
                     VFNSKQKKVYSDFGELEFTKFGLDGPIIKSASCRMKDTRKENYTILLDLKPALDEEKL
                     DKRVQKDFQKYTNKKFEKALDDLLPKKLIPIIINLSEINPNTVVHQISREQRKNLVHL
                     LKNLKFTVKRYRPIEEAIITSGGVKVNEINSSTMESKLVEGLFFAGEVIDIDAYTGGF
                     NLQIAFSTGYLAGFNC"
     gene            15908..16129
                     /locus_tag="KR231_002894"
     CDS             15908..16129
                     /locus_tag="KR231_002894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000002841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta-type small acid-soluble spore
                     protein"
                     /protein_id="HBH0005255.1"
                     /translation="MASNNNNNRTVVPGAKEALNQMKLEIANELGMSNYQQVDKGNLT
                     ARENGYVGGYMTKKLVEMAEQQMAGKSNR"
     gene            16318..16488
                     /locus_tag="KR231_002895"
     CDS             16318..16488
                     /locus_tag="KR231_002895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0005256.1"
                     /translation="MSSVNFEDLKNKFINSDLDEKIRIYTTTEGLSVEQFKELLKYYP
                     IQHLSKLEKALG"
     gene            complement(16581..17042)
                     /locus_tag="KR231_002896"
     CDS             complement(16581..17042)
                     /locus_tag="KR231_002896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0005257.1"
                     /translation="MQIEQLDLETRNKIYCYTKKILRKYQKGITSGKLTADKFADNIL
                     SQDFISSILNEKIVNETNFKISYRNYIETLINIQNENLSNLRKKSTKTAKCFNISQIT
                     QLKNLLSNTGYNLLIPYKYLTARDIEGIVTLINTGSIELGNERIYNYISKA"
     gene            17225..17692
                     /locus_tag="KR231_002897"
     CDS             17225..17692
                     /locus_tag="KR231_002897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0005258.1"
                     /translation="MKMLNGIIKLFYSEIVKTKINNLDSSGYSLRDECKEIRNITLKI
                     DSVFFKLLKLAFGSILLMVAFNLNMVLGIGVFLVGVVYILYKRNMEEQVKEHINNVKN
                     NIDISKITFMDEKGRTGLNALITLLLIGLLTGFNWILVASFVVVFVFTIKNVC"
     gene            17735..19498
                     /locus_tag="KR231_002898"
     CDS             17735..19498
                     /locus_tag="KR231_002898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpoIIE family protein phosphatase"
                     /protein_id="HBH0005259.1"
                     /translation="MTNGSYKMKNLVEISAMVTESTDFFNIKDDIIEKMLEVVHPTKA
                     CVNLFYKNDSKYAYLVCSQTLEYVPQIFPINSLKGAKIDFDTYPEYIHEAVNEKKIIY
                     VENVFEDSRAEGERDLAKAEGYIGRIVFPFIINNVVVGFMTCFLKEDDYITEQDIDFI
                     SSVASLLSLSIEITNKNNNVQILIDKLRGSISAINEATKKLYLNKSIDGFLENLSKQA
                     CNITNSKEALIIINSHHNKDAIVSCYNVEQKKKTNLYPMIDMFLKKESLGGYLNNLKP
                     CSKKGINLESYIYYKLQDKNETIGCIVCANSKNYTSDDLNILSILSKQVSVGMQLYEH
                     NEKEVKHKVLENELNILNKQQQLIMDKGKMDCNDEKELYFYHKPARVVGGDFYYATKV
                     DDEHIVYIVADVMGHGMVSNYVVAMIKGAFKVLCNQYNTPREIMTNLNRMLYDEFDKM
                     GVFTTCLIGIIDTKENMITVSNAGHYSPVVVKKDGTIENNLNCKKGIPIGIMEDATYE
                     NNTLSMEDYAMVCMYTDGILEIKNSSKEEYGINRLENFLKENFRLNQQLIVENLKLDL
                     KNFSSKDNYDDDILIVMLKDR"
     gene            19506..20114
                     /locus_tag="KR231_002899"
     CDS             19506..20114
                     /locus_tag="KR231_002899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin family protein"
                     /protein_id="HBH0005260.1"
                     /translation="MDSNDKKGLKSPEIIIINGSPRINKNCSFIANEVKAMLEECGLS
                     CKIFNIYNMDIEYCTACGFCEKTGYCKFNDDMKPLYKMFDDSKGTIVISPVHFDSISA
                     KLKTVVDRTQAIYASKYVLNKPSIDRSKKRIGMYIAVGGSKSYDSQFKGGQIVMDFFF
                     KSINTKLLHNIYLNNTDDVSYIDNQEFKDIIYKNLKIYIDSI"
     gene            20186..20755
                     /locus_tag="KR231_002900"
     CDS             20186..20755
                     /locus_tag="KR231_002900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate propanoyltransferase"
                     /protein_id="HBH0005261.1"
                     /translation="MKLPIALSNKHVHLSQADIDVLFGAGHELTKFKPLSQPGQYACE
                     EKVDLVGPKGTLKGVRVLGPARAHTQVEISLADGFPLGVKAPIKESGDIAGTPGVKLV
                     GPAGEVEMKEGVIVASRHIHMSNEDAAKFGVTDKQIVKVKTSGPRALVFENVLVRASD
                     SFNLEMHVDMEEGNAAGVKNGDLVELIVD"
BASE COUNT         7685 a         2837 c         3954 g         6494 t
ORIGIN      
        1 ggaaataatc agatgtatca tgcaggcgac ccgataggat atgcagacct aagtagtagt
       61 tactggcaac agcacttaat cggtgcagga cgagtaaaac aatagaaagg acttgaaaat
      121 atgtttaaga aaaataagaa acagacagaa actgtcaaag aaccaaaaga aaaaaaggtg
      181 cgtactgtca aggtaggcac acataagaaa accatgattg cgttgtgggt ggtgcttatc
      241 gcaagcgtga gctttggggt gtataagaat tttacggcta tcgaccagca cacgacccat
      301 gaaaaagaaa tcattgaact tcgtttgcag gacaccaacg ggatagaaaa tttcgtgaag
      361 aactttgcga agtcttatta cacatggagt aacagcaaag aagcgattga agcaaggacg
      421 caggcaatca gcggttatct gacaaaggaa ttgcaagact tgaatgttga tacaatcaga
      481 acggatatac cgaccagctc cacagttaca gatgtgattg tgtggcatat cgagcaatcg
      541 ggaacggaca ctttttctgc tacctacgaa gtagatcagc agataaaaga gggagaacag
      601 acaagcaatg tgaaagcgac ttatactgta aaagtccatg tagacgctga cggggatatg
      661 gtaatcattc agaaccctac tcttgcacca gcaatcgaaa aatcagacta tgagcctaag
      721 acaccagaag cagacgcaag cgtggacgct gatacggtaa atgacgctac cgcatttctg
      781 gaaacattct ttaagctcta tccaacagcc acagaaaaag agcttgctta ctatgtatct
      841 ggaaatgtga ttgagcctat cggcagggac tacctttatt ctgaactggt aaaccctatc
      901 tttacaaaga acggggataa tgtgaaagtc aaggtagcgg taaaattcct tgataatcag
      961 acaaaggcga cgcaggtatc acagtatgag cttgtgctac ataaggatag caactggaag
     1021 attgtaggat aaaagaaaaa ggcttgcagt tctgtattga tttgcaagcc taaatatatt
     1081 atttatactt ctggaaaatc ccgactaata aagtatctat cgcttcagct aattcaaatc
     1141 taactttatc tgaggcagaa aaagcgtttc ctaattgcaa agttgtataa ccgtgaatta
     1201 ttccagtaag catatttaat atttcaagtg ttttgtcttt gttaagactg cacgattgga
     1261 taagagtagt taataatgaa agatagttgt taaaaatggt tgctgtttcc tctgttccgt
     1321 gccacacagc ccattgaatt gtttcataaa ctccggggtg ttcaatcata tagtttaggt
     1381 attcgataga aactaactta attgcttctt tccctatttt tccaacggca attttcatca
     1441 ttctttcatt catgtcacgc ataccattat gagcaacttc taaaagaaga ttatctaaac
     1501 tttctatgtg attatataaa gatggtgtac gaatgtttaa tttttgagca acagctttta
     1561 acgaaacgtt atttaatcct ttttcatctg ctaagtctga tgttgctttt attactgctt
     1621 ctttagtggt tttcatagtt atgcacctca ttcaaaatat catacaaaca caattctagc
     1681 taattgaatt agtgtagtca ataacacaat tagaaaatta tgattattta ttgactttct
     1741 tacaaaaaca ttttaaaata ctaattagat tagttaaatg actatttaaa atagtatttt
     1801 gaggagtgat tatatgtgta caagatttgt ttacaatggt atagataaaa ttgttggttt
     1861 taattttgat attgaccttt ctgtatggga tcatactgta attaccgaag aaaatagatt
     1921 ttatattggt attaaaatgc ctgacggtct gtatcattca tttcatggga taaataaaaa
     1981 tggtaatgta ggaacacttc tttatgttca tggtaatgaa aatgcaaggt atatagaaag
     2041 cgaggattgt attacaatat ctgaattaac agaaaaattc attaaggcag agatttcttt
     2101 tgataaagcc ttggacattg ttaaaaagaa aaaaattatt tatgcaccag atgctactat
     2161 gcaagctatg ctttctgata aaaaaggacg agttttaatt attgaacctg gaattgggta
     2221 tagatatgaa caagaaaatt tttcacttat tacaaattat tctattctaa aaccagatat
     2281 aacaaagccg tacattgttt ctggggatac aagatacgaa gtggctaaag agttattggc
     2341 aggatatgat aaagattttt cagtaaatga cgcatttaaa gtattaaaat ctgtttctca
     2401 aaaagacttg tgggcaacta gggtttcatt tgtatattct acagaaaaaa ataaagttta
     2461 ttatgtcttg aacaatgatt ttagtaatgt atttgaattt cagttttaat actaatgaat
     2521 ttataaattt gcaattatga taagaaaggt tattatgata ggactaaaaa agcgagatat
     2581 aaaaaaagcg ttgaaagctg gtgcaaaagc tggcggtgta tcattggctg atgttcgggc
     2641 agatattgaa gcgacgattg atgaagctat gaatagcacc gccccagaag tgcaggcaaa
     2701 tttcaaaaag tattttggta ataaacgccc taccccagaa gaatatattt acaagattac
     2761 caaaaagaca aagatttgaa aaaaggcttg ctccatacat agtgtatgat ctgcaagcct
     2821 taatctattt cagaggaaat ttaacagtaa aagtagcacc tccaccagca gtatcattga
     2881 taatgataat accgttcagc atttgagtta attctttggc gatacttagt cccagtccaa
     2941 aattcgattt gttcgtatgg gacttgtcgc cactataaaa tcggtcaaag atatactgct
     3001 tatcttcatc agaaatgcct tgcccgtggt ctaccacaga aaaagcaata tttttttcgg
     3061 tggcgattac ttctatctct attaaagaat tattcttgga atgttgaatg gcattatcca
     3121 taaagacaca caagatttga aataatcggt ctttgtcggt aaacatagca ggataacttt
     3181 cctcggataa atgcagtttt agttctaaat tctgcttcat gcagacgggt tcgtaggttt
     3241 catataacgt aatgagcaag gtatctacat tgattgtgct tttatgcaat gtccatgttt
     3301 tagcgtcgga agaagccaaa agcaacatat ctttgactaa acgggataac cgcatacatt
     3361 caaaatctat ggtctgtacg gcttgctttg cctgctcgtt taaggaaaca ttatcaagaa
     3421 gcatatccgt gttggaaatc ataacagcaa gtggagattt taattcatgg gacgctgttg
     3481 caacaaaatc tttttggctt tgcagtattc gttccgttgg agcaaacgac tttttcagca
     3541 gataacgggt cagcacgata acaacgatac aagccaaaaa ccagataaga agatatatag
     3601 gcaatgtttt ttgtaaaata tccgtcaaac tggctgtctg ataaagaaag gttgcatgat
     3661 acacggtatc atttgctgtc ctaattgtag caggaataac aaaataagta tcgtgatgtg
     3721 ttcctcttat ttccagaaaa ccgccttgtg aagttgtgct gttttctatt tgtgataatg
     3781 gttgtgtaga aatctgcttt tctacatcat gcaacagatt gtccgcagaa gttggaaatg
     3841 ggaaatcact ctgataaatg gtattccccc ttgtatcagt aattaaagaa aaaatatgat
     3901 aactctcttc gtaggttttg agtgctttgt ccatatccga agaagcactt tccacttgat
     3961 aaatcagcaa ggttgtcaat ctctgaaata aggtgctttc gttgattttc tctgtatgaa
     4021 ctgtgttcgc aacgacaaag gaaatcacaa gggtaataat cagcataaca gaacttgcaa
     4081 acagaatatg aagttttcgg tataagttat ttaacatgtt tctttctcca gtttgtaccc
     4141 tgcaccgtag accgttgtta ttttacagga actttttaat tcttttaggc gttttcgcag
     4201 aaaagaaatg taactgtcta cattgccagt ttctacctcg gaagaactgc cccagatttt
     4261 aaggattagc tgttcacggg aaaatagtgt ttctgggttc tgcataaata caaaagtcaa
     4321 ctcggtttct tttgaagtta ataaaagaga attgacgggt gtagataagg ttcggctgtc
     4381 tttatcgaaa gttaaatctc catattctaa tttggaagat aactggatat tggcagggcg
     4441 tcttgttaat gcccgaactc ttgcaagcaa ttctttgata tgaaatggct ttactaagta
     4501 atcatcagca ccgccgtcta aaccctccac ccgattgtca agggtactca tggcagtaat
     4561 gataaggata ggaatagata ttccttttct acgcatagat tttatgattg ttaagccgtc
     4621 aataatcggt agcatacggt ctacaatggc gaggtcataa gcatagtctg tatttaaagc
     4681 gtacagcata gcggtttccc cgtcattgca acaatcaacc atatagtttt ctttttcgag
     4741 agaaattttt atatttttac ataactctaa atcatcttcc agaagaagta ttttcataat
     4801 gtatcaatcc ttttctatat aaattataga cagtataaca gaaaagtctg taaaaatcct
     4861 ctaaaaaatg atgatgattt tcttactttt ttacaggatt tttagaatgg tttgctttta
     4921 caataggggc atatcgaaca agaaaggtgg aatacaaaaa tgaaaaaaac aaacatcagt
     4981 aaatttgtag cagttggatt atgtatctgt gcattgacgg ggtgtggtgc aagtccagat
     5041 gagaaaccag atacgtctaa tcctattgtc aattctaata cgaatgaaga aaatgcaaat
     5101 ggttcttcag aaaataaagg aaacgacata ttagagtctg ctaatttgat aggaagtgtt
     5161 ttggaattta cagacaatgg ttgttccgta agtcaagcaa aagaaactga gggtggagct
     5221 agcctgcaaa tcgaagcgtc gggattggaa aataaagaca atgctgtttc tgtaacctat
     5281 aacccagatt gtgaattttt tgttgcgaca ctaaataaac agttgggttc tgttacgaat
     5341 ataacaacgg ggtctatatc cgatgtaaag aaacaatcaa atgtatatct ctatggagaa
     5401 ttttcagaca cacttcattt caatgcaaca aaggttgtca tagcccgttg ggaatagagg
     5461 tgtgaagtat gaagttttat caacttggtt ttcgctattt acagcgaaaa aaaggaaaaa
     5521 ccattcttct gttgattgtt ttgatacttg taaacagtat gattttaggt acaagcatga
     5581 ttttaaggac tacaaatgag tccaaacaag ccatgcagga aaagacaaac tctaagattg
     5641 tggctgaaat tacaagtaag gacagcaaga taacagagaa tgaagtaaac aagattgaaa
     5701 cgctggaaga tgtttcgtct atcaaccgta tcggcagaca agaggtattt ccgaatgatt
     5761 ttgctcccgt tacgctcaat acttctacga atgaggaaaa tttgaaaata gcgttgctct
     5821 cctatgatga tttggaaaag gacagccctt tttcagaaat gcagtaccgc ttatcttctg
     5881 gcgattatat caaacacgag aaaaaaggtg ctgttatcaa tgcgaacctt gcaaatcaaa
     5941 atgagctaaa agttggagat acgattgaat taagtacaga aaacggaaca aaagtatctg
     6001 ttcaaattat tggaattttc atgtccgcag gaaatgtgga aaaagaccag ccaacagaaa
     6061 ctaccgcagt caatcgaata gaaaatcaag tctttattga caacagcact tataaagaat
     6121 tgttcaaaga agctgaattt gaaaaactct gcgtttattc aaaaagacca gaaaaattag
     6181 atgtgctgga aaccagcttg caaaaaatat tcggaaatga tgtagaactt agcacttccg
     6241 atacccttta tcaacagatg tctgctccat tagagcaaat cagtaaggtg gcaaatctta
     6301 tgctggtact tacattggta actggtactg ttgttgtttc cctgctgtta tgtatgtgga
     6361 tgcggacaag gcaaaaagag gtggcaatct ttatgagcct cggcaagaca aaaagtgaaa
     6421 ttttcctgca aactttatta gaagcaggca gtgtatttac actttcggtt ttaggagcaa
     6481 cagccattgg taaattgttc tcgggcgttt tgcaaaatgt cattactggt tcagaaacag
     6541 taacagaaaa tctgaaagtg gtgttgcaga tacaagatat tggaatgttg ttccttttag
     6601 gtggtgcagt tattctggtg gcattgtgct gttccattct tccgatatta cgagcaaacc
     6661 caaaagatat attagcgaaa atggagggat agtacatgaa tttttttgga ttggcaaggc
     6721 gttctgtgtt cagaaagccc ataaaaagta ttctcttatt gttgattgtt tttgcaatca
     6781 gtaccctgct tcttgcaggt gtggcgagca aaaatgccag tattgaggtg caggacaaaa
     6841 ccagacaagc cataggtgca ggctttcttt tagaaagaaa tgcagagtac cgaacaaaac
     6901 gagttcgtga atactcagaa aagattggta atgataagga aggtagtttt ggtggctacc
     6961 atcaggaaaa agagattatc aatggtgtgg agacttggtc aggctggaca acaaatgaat
     7021 ttgaaagctt agatataaaa gacattgaga aactggcaaa aacaaaagga attgctgatt
     7081 acaatattac aacagcaaca actcctgtaa accctgtaaa tttcaaaaga attgaagata
     7141 aagatgtaga ccaaagtgta gatgagggag gtgtaagctt aattggaaac aaagatatga
     7201 aacttgacag aaatgtttta tctggaaacc tgcatatcaa agagggacga atgataaccc
     7261 cagaggataa agatatgtgt gtcatttcag aggaacttgc aaagcaaaat aatctgaaaa
     7321 tcggcgataa gatttctttt aatgattacc acgatactgt aaattcaaag gtatcagaag
     7381 ctgagattgt tggaatttat caagtggatc aaaagatgtc cccacttatg cagggagata
     7441 cttaccgttc ggaaaatgta atatttacag atttgagatt tccagaaaag gcagagggtg
     7501 aaacaagtcc attatatgaa agagcctatt tcaaagtaga agatgtggaa gcttacgacg
     7561 aagtaaaaga aaatctgcaa aaagtagaca tcaactggga gcaatatgat ttgattgaca
     7621 ataacggaaa ttccgaaacc atgtcctcaa acttcaatga tttagcaaaa gtaagcgaaa
     7681 tgatgatatt ggtaatctct gttgcaagtt ttgttatcct tgttttagta tttcttttct
     7741 ggctgaaaaa tcgagtgcag gaagtcggca ttttcttatc tctcggtgtt ccgaaattca
     7801 gaattatcgg gcagatttgg agtgaagcga ttatgattgc tgttctttcc cttatgctat
     7861 cctttgctgt cgctcctgcc gtttccaaag taactgcaaa ttatctggta tcacagcagg
     7921 ttcagcaaat gcaggaagaa gaaaaaaata acgagggaaa agtatccaca gaatatgttg
     7981 caccaaagca ggacgtgcag aatatcagcg tagaggttac gccagaaatg tatctgttgg
     8041 acggtgtaag tgttcttgtg ttgataacgg cttctgttct ggtatctgga attgtaatac
     8101 taaagagaaa cccgaaagat attttatcgg aaatgagtta ggaggacgac gaaaatgtta
     8161 gaagtaaaga atgtaagcta tgcttacaaa accaaaaaag ataaaaccat tttgaataac
     8221 gtatcagcta cttttgagga gggtatcttt tataccattg tcggtccgag tggtgcagga
     8281 aaaacaacac tcttatcctt gttagcaggc ttggacacag cagtaaaagg gactgtcctt
     8341 tgcaatggcg aggacattac aaaaaagggg ctgaattacc acagaaagca taatatctca
     8401 ttggtatttc aaaattataa tctgattgat tatttgacaa cggttgaaaa tgtcaaatta
     8461 ggtggtagtg gaaatgctga aaaattattg gaagaagtcg gcattggaaa agaatactgg
     8521 cagagaaatg tattgcaact atctggcgga cagcaacagc gtgtagcgat tgcaagagca
     8581 ttagccagcg acgctcatgt acttttggca gacgaaccga cgggaaatct tgacgaaact
     8641 accgctgatg aaatcattgc tttgctgaaa aagactgcac atgaattagg aaaatgtgtt
     8701 gttgtggtta cacacagtaa gcatttggca gaagaagccg acgaaatctt agaaattaaa
     8761 aacggtgcaa tttcttttct gtctgattaa attagaatag tgccgtaaag gagttgtcat
     8821 tatggaatat tttagatata cctcgacgca atcagtttga acctaacggc atttttataa
     8881 caactgaata tagcacagtt ttaaaagctc gtacagacta tatgttttgt gcgggctttt
     8941 ttcatgccag aaaaaaattt tttaaagttt tttcgatttt ggttacgctg tcccccactt
     9001 tcaacgcggt atatatgaaa aggggcagac acctcttttc gactagcgaa aggaggtgag
     9061 gaaaatgaaa ccgtcagaac tacaagaaaa aacctgtcat caattcgatt gtgctattaa
     9121 aacagttata cgtcatagag cgattgactt ctatcgagcg atacgtcgtt cagagaaaaa
     9181 agaaatgcca ttcgccgaaa ttatggacga cctcttaaat tccataggta cagaagatac
     9241 atattctacg gattatgttg cggtatttga agtctgtgga gaaaaagtat caatcgaaga
     9301 tgaacaactg gctcgtgcat tgaaagctat tgaagaacga aagcgtaata tcgttttaca
     9361 gtattttttc attggggaca cggacactta cattgggaaa atgcttgact gttccagagc
     9421 gaatgtaacg aagtgcagaa tacaagcact agacaagtta aagcaactga ttgaggagga
     9481 aaaagaaaaa tgccaaaaga gctgacaccg actttcacgg ttatttccaa agcctgcgac
     9541 ggcgacgaaa cagcaatttc aaaaatcttg gaattttatg acccatatat caatcggtgc
     9601 tgtatgcgtc cattttacga cgataacaac aacttacgtc ttgcggtaga tttggaaatg
     9661 aaaggtttta tcaaagaagc gattattcgt aaaatcttaa actttgatat taaacgcttc
     9721 taattcatat cgggattgat tatgcccgtc tggtctttga caactgaata aagcagacag
     9781 atacgtttgt gagatagcaa gccacgggga ctgtacgcca cgaccttttc aaaagaaagc
     9841 gagcgaccca cgcagtgatc cgagagcgac cgttggaaaa gtcgctttgc cacgacctat
     9901 cctcacagaa taatgatacg tccgcatggt gcggttctgc ccacaggaat gggaatagtt
     9961 gagatactaa cggagctttc caaagccgtc tgcctgcttg taaaaaatga cacacagtaa
    10021 agggggtgca tagattatga acaatactga tgtgcctatc tgggaaaaat atacgctgac
    10081 gattgaagaa gcgtccaaat acttccgcat tggcgaaaag aaattgcgta aattagccga
    10141 agaaaatctt gacgctggct gggttatcgt gaatggtaat cgtattcaga ttaagcgaaa
    10201 acaatttgaa aaaatcatag atacattgga cgaaatctaa tgtcattgag ccgtagatat
    10261 ggtataatat tagtagcgta tcacggctca ttccatgacg gaaaggagct ttacactatg
    10321 tctaatgtga aacgaaaaga cagtaaaaat cgcaatttgc gtaatggaga gagccagcga
    10381 aaagacggaa gatacgttta taaatatacc gatatatacg gaaagccaca atttatctat
    10441 tcttggaaac ttgtaccgac agacaagaca cctgctggaa agcgtgatga tatatcgttg
    10501 agggaaaaag aagcacagat aaaaaaagac cttaacgacg gtatcgacac agtcggcggt
    10561 aaaatgacag tctgccagct ctacgacaag aagaacagcc aaagaaagaa catcaaaagg
    10621 gctactgaaa aaggacgaca gtatcttatg aacgctctga aaaatgaccc attgggtatg
    10681 agggcgattg atacggttaa gcagtcggac gctaaagaat gggctatcag aatgagcgaa
    10741 aaaggatatg cctataaaac gattgataac tataagcgtt ccttgaaagc gtcattttac
    10801 atggcgatac aagacgactg tatcagaaag aacccatttg aatttaagtt aagtgatgtt
    10861 ctggaagatg ataccgaaca gaaagttatc cttacaccag agcaggaagg acgcctgctt
    10921 gcctttatgg aaaaggacaa gatttacagt aagtattatg atgaggttgt gcttctgctg
    10981 gaaacgggac ttcgtatttc tgaattttgc ggactgacga cgcatattga tatgcagaac
    11041 agaatactca atatagacca ccagttattg aaagatagcg aaatgggcta ctatattgaa
    11101 acgccaaaga ccaaaaacgg aaaacgggaa cttccattga cagaacgggc ttatcaagca
    11161 atccaaagaa tactaaagaa cagaggaaag gcacaaccgc tgattgtagg tggttacagc
    11221 aatttcctat tcttaaaccg tgagggtttg cctaaagttg caggaaacta tgagggcatg
    11281 gtgcgagggc tgattaagaa gtataacaag tatcacacgg acaagctacc gaacatcacg
    11341 ccacattcat tccgacatac ttattgtacg aatatggcaa acagaggaat gaacccaaat
    11401 actctgcaat atctcatggg acacgctaac ataaccatga cacttggcta ttacgcacac
    11461 ggcacatttc aatctgcaaa agcagaactg gaaagactgg cttgttaata tcggagctta
    11521 tatttactac tcatttacta cttttggttg cattttcatg ctggtaaatg ccagcttatg
    11581 caaggtatct tccaaaaaga aaataccgat aaagccctaa aatacgggat atatcggcat
    11641 ttaccaactt atgaaaagat aatcagaaat ttagtaagtt tttaaaataa aaattgcttt
    11701 aagagatgat attaataatt tattttcatt aggttttaat atacatactc taaagaaata
    11761 ctcatctaga ccttcaaatg aacaacaatc tcttattatt attttttgtg gaagcaattg
    11821 ttctcgaaga gatttagcag tcaattcctt tgtcttgatt ttacacaata tgaaattgcc
    11881 tttagtattg tatatatcta agctttttat attcttaagc tctttaagca ggtaatctct
    11941 ttcagtgttc attaaggaaa tagtatttga tataaaatct aaatcactaa acatgatttc
    12001 acccatttta gaagctatta tgtttatatt ccataaatct agatttttat ttatttcatt
    12061 tttgacatta gtgttagata taagaccata tccaagcctt attccaggcg ttgaaaaaaa
    12121 ttttgatgta cctcttataa cgaataaatt agaataatca tcaactaatt gagtacaaga
    12181 gtatgtatct gtatcagtaa actctacata agtctcatca atcattaaaa atgagtctgt
    12241 attttttaaa atttctctca cttctacttt agtaaatgca aatccagttg gattactagg
    12301 attacagatt actaccaaat cataatcttt agcattgata gtttttataa gattttctaa
    12361 atttatatga aaattatctt cttcttttgc aaagtatttt tctatagaac aattaatttt
    12421 agataactct ttttcatact ctgaataggc tggagagagt aaaagagcct gtttagggtt
    12481 aattgtatgt ataaatgatg aaattagttc tgtagctcca ctgccaagta ctatattatc
    12541 tatagaacat ttgcagtaat tggatataga agtttttaag tctatgtaat cagggtcagg
    12601 atacatagat accatatcta tattgtttac aatgtattgt ttggctaaac ttgatgtacc
    12661 aaaaggattt atatttgagc taaaatccat aaattcttcc tttgaaaagc catacttact
    12721 agataaacta tataaattag ctccatggtt tgtgctcata aaagtacctc caaaaataaa
    12781 attatataat cgataaaaat aactgattaa tatatgtaca tatagattat aatacaaagg
    12841 aatcgttatt ccaaattttt aatggaaaaa gcaaaaaagt atggataagc tgttaattta
    12901 ggtttaaaaa tgatgaaaaa gattttaatt gatattttgg tatgctataa tatataagtt
    12961 aatagaagga aagcgggagg atacaaaatg tacaaagtta caggaaaaat gttgacagaa
    13021 gaacaaataa aagaaaaagt ttatgaatta ggaaaaaaga tagaagaaga ctttaaaggc
    13081 gaagatttac tagtggtagg tatacttaaa ggagctagtg tatttgtttc agatttaata
    13141 agatgtatag atttggatgt aaatatagat tttatgagtg ttacaagtta tggaaactca
    13201 acagagtctt ctggaacagt taaaatatta aaagatttag atgtagatat tgaaggaaag
    13261 aatgtgttga ttgtagagga tataatagat tctggtttaa cattaagtaa tctagttgca
    13321 gctttaaaaa ctagaaatcc aaaatcttta aaactatgta ctctacttga caaacctcag
    13381 agaagaaaag ctaatatacc tgtagactat gttggatttg ttatagaaga caaatttatt
    13441 gttggttatg gaatagacta tgctgaaaag tatagaaatt taccttatat aggtatagtt
    13501 gaggatgtag aatagattta aatgtgaatc aaaagcacta atttctaagg gagttagtgc
    13561 tttttagtta attatataaa attttagtaa aggagacatc tatatggata ttcagttaaa
    13621 tatattatta tttttccaaa atttaagaaa tccaattttg aactttatat ttcttgtctt
    13681 tacaataagc acagaagcac cgttattaat attaattaca acaattatat actggtgtat
    13741 aaataaaaaa tgtggacaga aaatactgtt tgctataatt ggaaattttg ttgtaaattt
    13801 aggcatcaaa gagtttgtaa aagctcccag accaatagga ataaaaggtc ttgaatcatt
    13861 gagagtttct actgctggtg gttattcttt tccaagtgct catactcaaa ctgcaacaac
    13921 attttgggtt agtattatga ctatatttaa aaagagatat cttcatttaa taggtgcagt
    13981 tatggtttta ggagtaggat tgtctaggct gtatttagct gttcattggc caatagatgt
    14041 gatagcgggt tggatattag gaatattttt tacagttgta tttgtaaaaa tatttgacta
    14101 tattgatgat aataaaaatt atattttact tgtagtttta cttataccat ttataatagt
    14161 ggctatattt ctaaatagcc ctgaatattt tgaaaaattt ggtataatag taggatttgt
    14221 atttggatat atggttgagg atagatttgt taaatttaat acagataata ataacaaaaa
    14281 aataaatttt agtaataaaa ataaggggag taaaaatata attttttcaa gaatatgtag
    14341 gtttttggtt gggatagtaa caataggaat gttatatatt ggcattaagt tgtttatttc
    14401 aatgttaata gtcactttaa atataagtga ctctactatg agtataattt ttatgaattt
    14461 tattaagaat acagtagttg ttttttatgg aatagcagga gctccagcat tatttaaact
    14521 tttaaaatta aattgatttt aaggtataga gtcaatagtt taaattaaaa aaattaaggg
    14581 tagaaaagag tgattatttg aagaaggtag taataatagg tggtggacca gcagggatga
    14641 tagccgcatc aactgcatgt gagaaaggct atgatgtaac attaattgag aaaaatcata
    14701 aattaggaaa aaaacttgca ataacaggaa aaggtagatg taatattact aacgcttgtg
    14761 aaatagagga attaatagaa aatgtaccta caaatggaaa atttctttat agtgcttttt
    14821 atacttttac aaatgatgat gtaataagta tgtttaataa tcttggagta aagactaaaa
    14881 cagaaagagg aaaaagggtt tttccagaga gtgataaagc atttgatatt gtaaatgctc
    14941 ttgaaagaca acttaaaagt aagaaagtaa atatattatt aaattcgaaa gtagaaaaaa
    15001 taatatctaa aaataataaa attgaaaaag taattttaaa cgataaaaaa gaaattaagt
    15061 gtgattcagt tgtagtagca actggtggat taagttatcc acttactggt tctactggtg
    15121 atggatataa atttgcaatt tcacaggggc acacaattat agatacaaaa ccatctttaa
    15181 ttggtataga agtacaagaa agttttacaa aagatttaga aaaattatca ttgagaaatg
    15241 ttgaaataag ggtgtttaat agcaaacaaa agaaagttta tagtgatttt ggagaacttg
    15301 aatttactaa atttggttta gatggaccta taatcaagtc tgcaagttgt agaatgaaag
    15361 atacaaggaa agaaaattac actatattat tagatttaaa acctgcatta gatgaggaaa
    15421 aattggataa aagagttcaa aaagattttc agaagtatac aaataaaaaa tttgaaaaag
    15481 cattagatga tttacttcca aaaaaactaa tacctataat aataaactta agtgaaatta
    15541 atccaaatac ggttgttcac caaatttcta gagagcagag aaaaaactta gtccatttat
    15601 taaaaaattt aaagtttaca gtaaagagat acagacctat tgaagaagct ataataactt
    15661 ctggtggtgt aaaagtaaac gaaataaatt caagtacaat ggaatcaaaa ttagtagaag
    15721 gtttattttt tgctggagaa gtaatagata tagatgcata tacaggtgga ttcaatttgc
    15781 aaatagcttt ttctactgga tatttggcag gttttaattg ctaaaaatta cctgaattaa
    15841 aaatgtttaa aatcacataa tattatcagc aacacaaaat aaattaaaca gaaggaaggt
    15901 aatcaacatg gcaagtaaca ataacaacaa cagaacagta gtaccaggag caaaagaggc
    15961 tttaaaccaa atgaaattag aaatagctaa tgaacttggt atgagtaatt atcaacaagt
    16021 tgataaagga aaccttactg caagagaaaa tggttatgta ggtggataca tgactaaaaa
    16081 attagttgaa atggctgaac aacaaatggc tggaaaaagc aacagatagt tataaataat
    16141 tatttataac tattggctat tagtttagct agagctatct caaatataga aagtaatttc
    16201 taaattgaga tagctttttt ttattaaatt attaaataga tatattttta tgtaataaat
    16261 tttatgtatt tggataaaat aatacaaatg aatatgttac ataaggagtg atgtaaaatg
    16321 agtagtgtaa attttgagga tttaaaaaac aaatttatta atagtgactt agatgaaaaa
    16381 ataagaatat atacaacaac agaaggttta tcagtagaac aatttaaaga gctactaaaa
    16441 tattatccaa tacaacattt atctaaacta gaaaaagcac ttggatagca gtatttaatc
    16501 caaaattaaa aaggcaattt atttaatatt aaaaatattt tttattaaat aaattgcctt
    16561 tttataatag gtttaaatta ttatgctttt gatatataat tatagattct ctcatttcca
    16621 agttcaatag acccagtatt aataagagta actattcctt ctatatctct agcagttaag
    16681 tatttatatg gaattaataa attataacca gtattactta gtaagttttt taattgggtt
    16741 atttgagaga tattgaaaca ttttgcagtt ttagtagatt tttttcttaa gttagataaa
    16801 ttttcatttt gaatatttat taaagtttct atatagtttc tataagatat cttaaagttt
    16861 gtctcattga ctattttttc attaagtata ctactgataa aatcttgaga caatatatta
    16921 tctgcaaatt tatctgctgt taattttcca gatgttatgc ctttttgata ttttctaaga
    16981 atttttttag tatagcagta tattttattt ctcgtttcta aatcgagttg ttctatttgc
    17041 acaaaaccac ttccttctaa ttataaaaat atttattaaa aatctatact taactaataa
    17101 agcttcaata acttatttac aataaatact aaatcataaa atatttgtta ttttttatta
    17161 ttaccaagta taaaaaatat tataattgta aaacttacaa atatatgtaa aatatttagg
    17221 agtgatgaaa atgttaaatg ggataataaa gcttttttat tctgaaattg taaaaacaaa
    17281 gattaataac ttagattcaa gtggatattc tttaagagat gaatgtaaag aaatcagaaa
    17341 tataactcta aagatagata gtgtattttt taagctttta aagttagctt ttggttcaat
    17401 attgcttatg gtagctttta atttaaacat ggttttaggt ataggagtgt ttttagttgg
    17461 tgtagtttat atactatata aaagaaatat ggaagaacaa gtaaaagagc atataaataa
    17521 tgtgaaaaat aatatcgaca tctctaaaat aacttttatg gatgaaaaag ggagaacagg
    17581 tctaaatgca ttaattacat tacttcttat aggattattg acaggattta actggatatt
    17641 agttgctagt tttgtcgttg tttttgtttt tactataaag aatgtatgtt aaaatactaa
    17701 taaatagttt aatatatagg gggagaaatt gagtatgact aatggcagtt ataaaatgaa
    17761 gaatttagtg gaaatatccg ctatggtgac tgaatctaca gattttttta atataaaaga
    17821 tgacataata gaaaaaatgt tagaagttgt tcaccctaca aaggcatgtg tgaatctatt
    17881 ttataaaaat gattctaaat atgcctactt agtatgttcg caaaccttag aatatgtacc
    17941 tcaaattttt ccaataaata gtcttaaagg tgcaaaaatt gattttgaca catatccaga
    18001 gtatatacat gaggctgtaa atgaaaaaaa aataatatat gtggaaaatg tatttgaaga
    18061 ttctagagca gaaggtgaac gagatttagc aaaagctgaa ggttatattg ggagaatagt
    18121 ttttcctttt ataataaata acgtagttgt tggatttatg acttgttttt taaaagagga
    18181 tgattatata acagaacaag atatagattt tatatcatct gttgcatcac tcttaagttt
    18241 atcaatagaa ataactaata aaaataataa tgtacaaatt ttaattgata aactaagagg
    18301 ctcaataagt gccataaatg aagctactaa aaaactatac cttaataaga gtattgatgg
    18361 atttttggaa aatttaagta aacaagcgtg taatattact aatagtaaag aagctttaat
    18421 aattataaat agtcatcata ataaggatgc tatagttagt tgttataatg ttgagcaaaa
    18481 aaagaaaaca aatttatatc ctatgattga tatgttttta aagaaagagt cattgggggg
    18541 gtatttaaat aatttaaaac catgctcaaa aaagggaata aatttggaaa gttatatata
    18601 ttacaaactt caggataaaa atgagactat aggatgtata gtttgtgcaa atagcaaaaa
    18661 ctatactagt gatgatttaa atattcttag tatattgtcc aaacaagttt ctgttggtat
    18721 gcaattatat gaacataatg aaaaggaagt aaaacacaaa gttcttgaaa acgagttgaa
    18781 catattaaat aaacaacaac agcttattat ggataaaggt aaaatggatt gtaatgatga
    18841 gaaagaactt tatttttacc ataaaccagc aagggtagta ggtggagatt tttattatgc
    18901 tacaaaagtg gatgatgaac atatagttta tattgttgct gatgtaatgg gacatggaat
    18961 ggtatcaaat tatgttgttg caatgataaa aggtgctttt aaagtattat gcaatcaata
    19021 caatacacca agagaaataa tgacaaattt aaataggatg ttatatgatg aatttgacaa
    19081 gatgggagta tttacaactt gtttgatagg tattatagat actaaagaaa atatgattac
    19141 tgtgtctaat gcaggtcact atagtcctgt agttgtaaag aaagatggca caatagaaaa
    19201 taatttaaat tgtaaaaagg gcatacctat tggaataatg gaagatgcta cttatgaaaa
    19261 taatactctt tcaatggaag attatgcaat ggtatgtatg tacactgatg gaattttaga
    19321 gataaaaaat tcatcaaaag aagagtatgg tataaacaga ttagaaaact ttctaaaaga
    19381 aaattttaga ttaaatcaac agttaatagt agaaaatcta aaattggatt taaagaactt
    19441 ctcatcaaaa gataattatg atgatgatat tttaatagtt atgttaaagg ataggtagat
    19501 tgattatgga ttcaaacgat aaaaaaggac ttaaaagtcc agagattata ataataaatg
    19561 gaagtccaag aattaataaa aattgcagtt ttatagcaaa tgaagtaaaa gctatgctag
    19621 aagagtgtgg attaagttgt aaaatattta atatctacaa tatggatatt gaatattgca
    19681 cagcatgtgg attttgtgaa aaaacagggt attgcaagtt taatgatgat atgaagccat
    19741 tatataaaat gtttgatgat tcaaaaggaa ctatagtaat aagtcctgta cattttgatt
    19801 caatatcagc taaattaaag actgttgttg atagaactca agctatatat gcaagtaaat
    19861 atgtattaaa taaaccttca attgatagaa gtaagaaacg gataggaatg tatattgcag
    19921 tgggagggag taaatcatat gattcacagt ttaaaggtgg acagattgtt atggattttt
    19981 tctttaagag tataaatact aaacttttac acaatatata tttaaacaat acagatgatg
    20041 tatcttatat agataatcaa gaatttaaag atataatata taaaaattta aagatatata
    20101 ttgattcaat ataatttgat tttgtaggta atattatgta taattgtatt gcaataattt
    20161 aaataattaa aaggagggaa tttcaatgaa attaccaata gcattatcta ataaacatgt
    20221 tcatttgagt caagctgata tagacgtatt atttggagca ggtcatgagt taactaaatt
    20281 taaaccatta tctcaaccag ggcaatatgc ctgtgaagaa aaagtggatt tagtaggacc
    20341 aaaaggaact ttaaaaggag ttagagtact aggaccagct agagctcata ctcaagttga
    20401 aatatcttta gcagatggtt tcccattagg agtaaaagca ccaataaaag aatctggtga
    20461 tatagctgga actccaggtg ttaaattagt aggacctgct ggagaagttg aaatgaaaga
    20521 aggagttata gttgcttcta gacatataca tatgagcaat gaagatgctg ctaaatttgg
    20581 tgtaactgat aagcaaatag taaaagttaa aacatctgga ccaagagcat tagtatttga
    20641 aaatgtatta gtaagagcta gtgacagctt taatctagaa atgcatgttg atatggaaga
    20701 gggaaatgca gcaggcgtta aaaatggaga tttagtagaa ttaatagttg attaatatta
    20761 taaatagact ttatgctagt agatatttta tttgctagca tatttttaaa tgtaataaat
    20821 ttctatagga taaatttaat caattagatt aatttataaa ataaaggggt attataaaaa
    20881 atgtaataaa aacttacaaa aatatgatgt aatatggtaa aattatatat ataaaaattt
    20941 acatgtaata aggataagca ttttactttt
//
LOCUS       DAEPHU010000072        20515 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 01A10CD0081
            SAMN05941466-rid12468953.denovo.072, whole genome shotgun sequence.
ACCESSION   DAEPHU010000072 DAEPHU010000000
VERSION     DAEPHU010000072.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941466
            Sequence Read Archive: SRR6291087
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 20515)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20515)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068158.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 22:43:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,892
            CDSs (total)                      :: 3,805
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 87
            rRNAs                             :: 8, 1, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 55
            CDSs (without protein)            :: 55
            Pseudo Genes (ambiguous residues) :: 0 of 55
            Pseudo Genes (frameshifted)       :: 21 of 55
            Pseudo Genes (incomplete)         :: 28 of 55
            Pseudo Genes (internal stop)      :: 16 of 55
            Pseudo Genes (multiple problems)  :: 8 of 55
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20515
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941466-rid12468953.denovo.072"
                     /strain="01A10CD0081"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            69..1100
                     /locus_tag="KR231_002901"
     CDS             69..1100
                     /locus_tag="KR231_002901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S8 family serine peptidase"
                     /protein_id="HBH0005262.1"
                     /translation="MENICDMNNKVKVAVLDTGIDKEHDYLKDNLVGGIAFECMHDYI
                     FISDKFDDEDGHGTACASIIKKEYEDVELFVIKILRKDGITNIKVLEEALRYLLDTNI
                     RLINLSLSVIGVESVKGLFEVCYELFRKGKIIVCSLANDFDLSYPAMFNNVIGVRGFT
                     LDGDDSFWYNKKYDVQCVMDSNSYISCDINNSYRLPPKCNSYLSAKLTGKIAKILSEK
                     PGITISDLNDKLESLATRNHWDSCDFDECSRIVNFKLDLYDKENALFMKVADVVRDCL
                     DIEENNEKLFKGSLFNKEIGLVYDNCFNLLKKLEHRFDIKFNYMDISKYDLVSIYTLT
                     ELVERYKNL"
     gene            1233..2531
                     /locus_tag="KR231_002902"
     CDS             1233..2531
                     /locus_tag="KR231_002902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903674.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional folylpolyglutamate
                     synthase/dihydrofolate synthase"
                     /protein_id="HBH0005263.1"
                     /translation="MKYEEALEYISQTNKFGIRLGLENIGKLLELLGNPQETLNIIHV
                     AGTNGKGSVCSFVSNILRECGYKVGLYTSPYLETFTERIRVNGQNIPQDDVARIIELI
                     KEKIEIMVKEGYAYPTEFEVVTAMAFYYYSEQKVDFVALEVGLGGRYDATNIITKSLV
                     SVIVSISLDHTGILGDTIEKIAYEKAGIIKENGVVLVYDQTDEAKDVIKSVCKEKKAK
                     YIEVDFDDINIKKSDINSQIYDCTVMKETYRDLEIKLIGEHQINNSILAISVIKYLKD
                     INKLANINEESIRKGLINTKWPGRIEKIKENPIFIIDGAHNEDGAKSLAKALDKNFKG
                     RKLTLLIGMLEDKDIDSVLEILLPHFNKVITTTPSNPRAINSDILREKVLKYVDDVTS
                     KHEIEDAVNYTLETSSEDDIIISAGSLYMIGTVRTLVKKL"
     gene            complement(2645..2890)
                     /locus_tag="KR231_002903"
     CDS             complement(2645..2890)
                     /locus_tag="KR231_002903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR03905 family TSCPD domain-containing
                     protein"
                     /protein_id="HBH0005264.1"
                     /translation="MKVTFNPSGVCCREMIFEVDENNVIVDAEFIGGCNGNLSGLRSL
                     IIGQNALEVADKLNGIDCGGKGTSCPDQLSKAIRQSI"
     gene            3038..3904
                     /locus_tag="KR231_002904"
     CDS             3038..3904
                     /locus_tag="KR231_002904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YncE family protein"
                     /protein_id="HBH0005265.1"
                     /translation="MKIYISNYLSKSISIVDYSTLELEKEIVLEDNIYPHHFCIEKEK
                     NLIYIPSSSNGILYVLDLSNDKIIDTVSIGGSLSQVVLSDNELFVANEDSNSIYVLDK
                     NTLNPIGIIGVDNMPHGFDFDRESKKLYVPCINSIVCIDTINKNIQKKINMDFRAWHI
                     ELDKQKKEMYISTLDGKLIIIDEVSMDIKKVLYEFLLPVEIRFNYSGKKVYVADLGYN
                     NVRILDYTTSRYIGNIEINGIPQGLEISKDEKLLFVSDTQENSVKVYETANNKLIKEI
                     KVGKEPTTIICL"
     gene            complement(3908..4444)
                     /locus_tag="KR231_002905"
     CDS             complement(3908..4444)
                     /locus_tag="KR231_002905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4364 family protein"
                     /protein_id="HBH0005266.1"
                     /translation="MFENSSEELAYHKLLILYILEKIKMDLTNSQITQVVLETEMMNY
                     FSLQQLLSQLMESKFLTTYKDSDREYYALTQRGVESLEYFFNRIPTSVTEKIDKYIDS
                     NKENLLADTQVKSSFVKQSDNEFIVNLRVIENQSNLIDLNLNVSSEKQAKLICNNWKN
                     NASYMYAEVIDLLIRDIH"
     gene            complement(4635..4838)
                     /locus_tag="KR231_002906"
     CDS             complement(4635..4838)
                     /locus_tag="KR231_002906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta-type small acid-soluble spore
                     protein"
                     /protein_id="HBH0005267.1"
                     /translation="MSNSNRTVVPEAKAALNQMKLEIANEIGLSNYENIDKGNLTARE
                     NGYVGGYMTKKLVEMAERQMAGK"
     gene            5129..5893
                     /locus_tag="KR231_002907"
     CDS             5129..5893
                     /locus_tag="KR231_002907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HBH0005268.1"
                     /translation="MKREVKRTKALIYSVLFFSLLLVLIFVFVYGIKYICSKSDNSKM
                     PIYKVDTNEKKIALSFDVAWGTDNMDDILKILDKHNVKATFFLVGSWVDDNEEIVKAI
                     DEKGHEIGNHSNTHANLKEISKEDITKEIETTSEKIYNITGKRTNLFRPPFGDVNNKA
                     MDICSDLGYKVIKWDVDSIDWKELGPNHVIEKVIKESQPGSIVLFHANINDVDNYLDT
                     IISRLKKDGYSLVKISDLLYKDNYVVDSNGVQKTKN"
     gene            6282..7595
                     /gene="prdC"
                     /locus_tag="KR231_002908"
     CDS             6282..7595
                     /gene="prdC"
                     /locus_tag="KR231_002908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proline reductase-associated electron transfer
                     protein PrdC"
                     /protein_id="HBH0005269.1"
                     /translation="MNKLYSILLKQHVGGPDKPVVSVGDVVKKGTLIAEPTGLGANIY
                     ASVSGKISEINDQAIVIEADEVQEDTFEPLKGEGILDLIKEAGVVGMGGAGFPTHVKL
                     NIDLNGGTILANAAECEPLLAHNIKEIEERPEIVYQGIKYAMEVTNAGKGMLAIKSKH
                     PKAIEAFKKVIKPGDNIEVAELVDMYPMGEERAIVRDVLGKLLEPTQLPSEANAVVIN
                     VETLTRIVEAVEQKRPVISKNITVVGQLNSGKESIVFEDVPIGTTVGELIERAGGIKG
                     EYGEIILGGPFTGKATTLDAPITKTSGGIIVTMPFVNEKRKMGLLVCACGPNEERMRD
                     IATKMGVTDIVSVQKCKQAQEIKGALKCENPGHCPGQAQKCIEFKKAGAEVILIGNCT
                     DCSNTVMGSAPKLKLGVYHITDHVMRTVNHPLIRRIKGDVRLKIK"
     regulatory      7999..8084
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01786"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="cyclic di-GMP riboswitch class II; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="cyclic di-GMP"
                     /db_xref="RFAM:RF01786"
     gene            8666..10915
                     /locus_tag="KR231_002909"
     CDS             8666..10915
                     /locus_tag="KR231_002909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cys-Gln thioester bond-forming surface protein"
                     /protein_id="HBH0005270.1"
                     /translation="MKTKIKKSSIISLVIAFSMVFTAFTPIVSYADEVTSNDTILNGE
                     EQSNGQTSDVEKPSDGQVPDGEKPSDSQVPDVEKPSDGQVPDGEKPSDSQVPDGEKPS
                     DGQVPDGEKPSDGQIPDGEKPSDGQIPDGEKPSDGQIPDGEKPSDGQMPDGEKTSDSQ
                     TPDVEKPSDGQMPDGEKPLDEQTPEEEKPLEEEIVIEEMSLKQDIDKILDMTLSQINK
                     IVYNFWEDEEDVKADEQSEINQVFTSEDSFISLWYDKKAKVKNSCLLKEIDGSDRPYH
                     DLRFDDITKTLTFDYVIKGLVGASSKDDKYVIEGEDGEQTAFCYNNHLRPPSSNGKSP
                     YLPAEDFNGQENQNEEAVKSILYAGSEFDGFGYKQQFNLGGEENELMTYSATQSAIWI
                     ILGQMDEQERLKQYQGSINLCDKLIERAKTEEERAEYQKKKEVAINIKAYLEALLKAG
                     REELKPNNTGKPSLSNGLTKINFEKNEDGTYETEAVALVGYSGVVKLKLPDGVTAYDG
                     DGNIIGTGEVEISTQQKFKLKSVGKPDAKANISAVSYDYIFPKAIQYYKAVLDLGQKD
                     HSSSLPSSKQNLLSYTIEKKNGQEVNFNIGLPTDDDDVVNPPVPPIDDDVVNPPVPPT
                     DDTNGHKPKPSPPIDDTVINPPVPPMDDTIINPPVPPTEDAVLNPPVPPMEDAVLNPP
                     VPPTEDTVLNPPVPSVSDTVEKTPELSRDDTIIKSPKTGDETQLMSYVFISVIAICGL
                     AYQCKIKRN"
     gene            11322..13082
                     /gene="prdR"
                     /locus_tag="KR231_002910"
     CDS             11322..13082
                     /gene="prdR"
                     /locus_tag="KR231_002910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-54 dependent transcriptional regulator
                     PrdR"
                     /protein_id="HBH0005271.1"
                     /translation="MFSIPEVKKVEEVMDTKFTTIDEDTRIEDAIKEMIKSNTKTLMV
                     IDSSDQLKGIISMTDIHNLYEMHKKYEGQPVKLIMKKDVIYVNEGLTLDECRDIMILK
                     NIGILPVLRDNKIIGVLKQEHIRDYLYMHLEDYGLTLKYIIGQIKEGICAINNEGVVI
                     LWNKFMEERYDIKSEDIVGRPMNEFLENTISEKVLNSKVGMSDLYFTDKKENMYALVH
                     ANPIFYKEEFIGVVCTEVDVTEAKILALELEKVNDTLKYLKNEVKNLSKGSFDKILGK
                     SYKLEKSKAIAKQVARTNSSIFIWGESGTGKEVFARAIHDYSERKGQFIPVNCSAIPN
                     ELFESEFFGYESGAFTGASKKGRIGIFELAKDGTVFLDEIADLPLSMQAKLLRVLQEK
                     EIRRVGGDTTIKINPRIISATNKDLSKMVKAEKFREDLYYRLNVVEIKIPPLRERKED
                     IGLLVHSFLEEICKQNNKPVLTISKDVIDIFQNYRWKGNIRELKNTIENIVVLSQNSK
                     IDVDDVPSYMMDSTNNSTEEEEYPLDLTKATQKIEIKNITKALKMSNGNKAKAAKILN
                     IPRTTLYYKIDQYKIDVSKI"
     gene            13511..15391
                     /gene="prdA"
                     /locus_tag="KR231_002911"
     CDS             13511..15391
                     /gene="prdA"
                     /locus_tag="KR231_002911"
                     /EC_number="1.21.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-proline reductase (dithiol) proprotein PrdA"
                     /protein_id="HBH0005272.1"
                     /translation="MSITLETAQAHANDPAVCCCRFEAGTIIAPENLEDPAIFADLED
                     SGLLTIPENGLTIGQVLGAKLKETLDALSPMTTDNVEGYKAGEAKEEVVEETVEEAAP
                     VSEAAVVPVSTGVAGETVKIHIGEGKNISLEIPLSVAGQAGVAAPVANVAAPVASAAA
                     EVAPKVEEKKLLRSLTKKHFKIDKVEFADETKIEGTTLYIRNAEEICKEANETQELVV
                     DMKLEIITPDKYETYSEAVLDIQPIATKEEGELGSGITRVIDGAVMVLTGTDEDGVQI
                     GEFGSSEGELNTTIMWGRPGAADKGEIFIKGQVTIKAGTNMERPGPLAAHRAFDYVTQ
                     EIREALKKVDNSLVVDEEVIEQYRREGKKKVVVIKEIMGQGAMHDNLILPVEPVGTLG
                     AQPNVDLGNMPVVLSPLEVLDGGIHALTCIGPASKEMSRHYWREPLVIRAMEDEEIDL
                     VGVVFVGSPQVNAEKFYVSKRLGMLVEAMEVDGAVVTTEGFGNNHIDFASHIEQIGMR
                     GIPVVGVSFSAVQGALVVGNKYMTHMVDNNKSKQGIENEILSNNTLAPEDAVRIMAML
                     KNAIEGVEVKAPERKWNPNVKLNNIEAIEKVTGEKIVLEENEQSLPMSKKRREIYEKD
                     EN"
     gene            15472..15756
                     /locus_tag="KR231_002912"
     CDS             15472..15756
                     /locus_tag="KR231_002912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0005273.1"
                     /translation="MDRLKYISSETFYEGIIVDIKGGGVTIDLKGRLGQFKIPNRMLI
                     TDYELKIGQEVGFMLSYPEVLSPEPNQEYVENIRREKEKQAEMQSKQEEK"
     gene            15794..16519
                     /gene="prdB"
                     /locus_tag="KR231_002913"
     CDS             15794..16519
                     /gene="prdB"
                     /locus_tag="KR231_002913"
                     /EC_number="1.21.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011986824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_except=(pos:16244..16246,aa:Sec)
                     /transl_table=11
                     /product="D-proline reductase (dithiol) protein PrdB"
                     /protein_id="HBH0005274.1"
                     /translation="MSLTTVQGLQSEIFVPITPPPVWTPVTKELKDMTIALATAAGVH
                     LKSDKRFNLAGDTTFRAIPNTATVDEMMVSHGGYDNGDVNKDINCMFPIDRLHELAAE
                     GFIKGVAPMHYAFMGGGGNQHVFTEETGPAIAAKLKEEGVDGVVMTAGUGTCHRTAVI
                     VQRAIEEAGIPTIIIAALPPVVRQNGTPRAVAPLVPMGANAGEPHNIEMQTHILRDTL
                     EQLVAIPSAGKIVPLPYEYKAHV"
     gene            16599..17357
                     /gene="prdD"
                     /locus_tag="KR231_002914"
     CDS             16599..17357
                     /gene="prdD"
                     /locus_tag="KR231_002914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proline reductase cluster protein PrdD"
                     /protein_id="HBH0005275.1"
                     /translation="MEEKIMRRLVIKPFHMNEVNFGSKTSIKKDVLTIDLSSIDEIKE
                     REELITDIKVDIIKPGDYDREINTIMDIIPISTKVLGRLGEGITHTLTGVYVMLTGAD
                     EDGNQMHEFGSSEGILKDQMVFGRYGTPSVEDYIIHVDVTLKGGLPFERTLPLAAFRA
                     CDDFIQEIRASLKMEDGRNATQVREYFDKIRPNAKKVVIVKQIAGQGAMYDNQLFSKE
                     PSGFEGGTSIIDMGNVPMIISPNEYRDGALRAMT"
     gene            17372..17839
                     /locus_tag="KR231_002915"
     CDS             17372..17839
                     /locus_tag="KR231_002915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proline reductase"
                     /protein_id="HBH0005276.1"
                     /translation="MGIGPSTKETSLHHFRDPLLDIVESDKDVDLLGVIVVGTPDGNE
                     NKTFVGQRTAAWLEAMRVDGAIVSSDGWGNSHVDYANTFEEIGKRDIPVVGVTFNGTQ
                     AKFVVSNQYMDTIVDMNKSKEGIETEVVGENNTNEIDAKKALAFLKLKMRKHG"
     gene            17857..18339
                     /locus_tag="KR231_002916"
                     /pseudo
     CDS             17857..18339
                     /locus_tag="KR231_002916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428088.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="proline reductase"
     gene            18359..19366
                     /locus_tag="KR231_002917"
     CDS             18359..19366
                     /locus_tag="KR231_002917"
                     /EC_number="5.1.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proline racemase"
                     /protein_id="HBH0005277.1"
                     /translation="MKFSRSIQAIDSHTAGEATRIVVGGIPNIKGNSMPEKKEYLEEN
                     LDYLRTAIMLEPRGHNDMFGSVMTQPCCPDADFGIIFMDGGGYLNMCGHGTIGAMTAA
                     IETGVVPAVEPVTHVVMEAPAGIIRGDVTVVDGKAKEVSFLNVPAFLYKEGVEVDLPG
                     VGTVKFDISFGGSFFAIIHASQLGLKIEPQNAGKLTELAMKLRDIINEKIEIQHPTLA
                     HIKTVDLVEIYDEPTHPEATYKNVVIFGQGQVDRSPCGTGTSAKLATLHAKGELKVGE
                     KFVYESILGTLFKGEIVEETKVADFNAVVPKITGSAYITGFNHFVIDEEDPLKHGFIL
                     K"
     gene            19486..20367
                     /locus_tag="KR231_002918"
     CDS             19486..20367
                     /locus_tag="KR231_002918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TSUP family transporter"
                     /protein_id="HBH0005278.1"
                     /translation="MVAILKALYVVFAAIFAVVFGKDVAKANKEGKLEEQSTPKVAVT
                     GFITDFFDTLGIGSFAPTIAMSKALKLNIPDKKMPGTLNVAHTIPVVTEAFIFTSIIP
                     VDGVTLVSMVVAAAVGSYIGAGIIAKMDERKIQLVMGVTLALTAILMLLGHPWINVLP
                     GGGNELGLTGVKLVIGVIGNFILGALMTAGIGLYAPGMAMVYFLGMSAKVAFPIVMGS
                     CALLMPVASMKFIKEDAYTKKASVIIAICGLIGVFVAAYIVKTLPMDILKALVIVVIA
                     YTSATMIMAANKNKKTA"
BASE COUNT         8175 a         2399 c         3824 g         6117 t
ORIGIN      
        1 ataaattgtg caacttaaat caaagtttaa gatgaactat taacatagat atattaaaaa
       61 cttttgtaat ggagaatata tgtgatatga ataataaagt taaggttgca gtattagata
      121 caggaataga caaagaacat gattacttaa aagataattt agttggagga attgcttttg
      181 aatgtatgca tgattatatc tttatatcag ataaatttga tgatgaagat ggtcatggaa
      241 ctgcttgtgc atcaataata aagaaagagt atgaagatgt agagttattt gtaataaaaa
      301 ttttgagaaa agatggtatt acaaatataa aagttcttga agaagcatta agataccttt
      361 tagacactaa cataagatta attaatttaa gtttatcagt cataggagta gaaagtgtta
      421 agggcttatt tgaagtttgt tatgaattgt ttagaaaagg aaaaataata gtatgttcac
      481 tcgctaatga ttttgactta agttatccag ctatgtttaa caatgttata ggtgtaagag
      541 gatttacttt agatggagat gattcatttt ggtacaacaa aaaatatgat gttcaatgtg
      601 ttatggatag caattcatat ataagttgtg atataaataa ttcctataga ttaccaccaa
      661 aatgtaatag ttatttatca gcaaagctta ctggtaaaat agctaagata ttatcagaaa
      721 aaccaggcat aacaatatct gatttaaatg ataagcttga atcattagca actagaaatc
      781 attgggatag ttgtgatttt gatgagtgta gtagaattgt aaactttaaa ttggatttgt
      841 atgacaaaga aaatgctctt tttatgaaag ttgctgacgt tgttagggat tgcttagata
      901 ttgaagagaa taatgaaaaa ctctttaagg gtagcctttt taataaggag ataggcttgg
      961 tttatgataa ttgttttaat ctgttgaaaa agctagagca tagatttgac ataaagttta
     1021 attatatgga catctcaaaa tatgacttag tttcaatata tacactgact gaattagtgg
     1081 aaagatataa aaacttataa ataaagattt gtagctaaat ttaatgtaga aggtattaaa
     1141 ttatatgtat tctttgtcgg tagattaaaa gtaaaaaata tactataatt agatagcata
     1201 agagaaaatg ccaatacagg gggagttaga taatgaaata tgaagaagca ttagagtaca
     1261 tatcacaaac taataaattc ggtataagat taggattaga aaatatcgga aagttattag
     1321 aattattagg aaatccacaa gaaactttga atataataca tgtagctgga actaatggaa
     1381 aaggttctgt gtgttctttt gtttctaata tactaagaga gtgtggatat aaagttggtt
     1441 tatatacatc tccatattta gaaactttta ctgagcgtat aagagtaaat ggacaaaata
     1501 taccacagga tgatgttgct agaataattg agttaataaa agaaaaaata gagattatgg
     1561 taaaagaagg ctatgcatat ccaacagaat ttgaagtggt tactgcaatg gcattttatt
     1621 actattcaga acaaaaggta gactttgtgg cattagaagt tggtttaggt ggcagatatg
     1681 atgctacaaa tataataaca aaatcacttg taagtgtgat agtatctata agtttggacc
     1741 atacaggtat acttggagat acaatagaaa aaatagcgta cgaaaaggct ggaataataa
     1801 aggaaaatgg agtagtacta gtatatgacc agactgatga agcaaaggat gttataaagt
     1861 cagtttgtaa agagaaaaaa gctaaatata tagaagttga ttttgatgat ataaacataa
     1921 aaaaatcaga tataaattct caaatatacg attgtactgt aatgaaagaa acttatagag
     1981 accttgaaat aaaattgata ggcgaacatc aaataaacaa ttctatcttg gcaattagtg
     2041 taataaaata tctaaaagac ataaataaat tagcaaatat aaatgaagaa tctataagaa
     2101 aaggacttat aaatactaaa tggccaggaa gaatagaaaa gataaaagaa aatccaattt
     2161 ttataataga tggtgcacat aatgaagatg gagcaaaatc tttggcaaaa gcacttgata
     2221 agaattttaa aggtagaaaa ttaaccttat taataggtat gttagaagat aaagatattg
     2281 atagtgtttt agagatattg ttgccacatt ttaataaggt aataacaaca acaccaagta
     2341 acccaagagc cataaattca gatatattaa gagaaaaagt attaaaatat gtagatgatg
     2401 taacatcaaa gcatgagata gaggatgcag taaattatac attagaaaca tcaagtgagg
     2461 atgatattat aataagtgca ggttcattat atatgattgg tacagtgaga actttagtaa
     2521 agaaattata attttataaa ataagtatac aaataaaaat ataaaaaaga gttgtctaaa
     2581 aaatggacaa ctctttttat ataaaataag tttttaataa ttttactgat gtttatataa
     2641 gtaattatat agattgacgt atagctttag ataattggtc tgggcaagaa gtaccttttc
     2701 caccacagtc aataccattt aatttatcag caacttcaag agcattttgg ccaattatta
     2761 agcttctaag tcctgataaa ttaccattac atcctcctat aaattcagca tcaacaatca
     2821 cattattttc atcaacttca aaaatcattt ctctacaaca tacaccactt ggattaaatg
     2881 ttactttcat taaaaagacc tccattaaat attatttctt tttttaacat taataataat
     2941 accaaatata tgcgtaataa tgcaactata aagcataata caagctaatg aaataatata
     3001 ttattgtagt atatgtattg tagagaggag gggttatatg aaaatctata tttctaacta
     3061 cttatcaaag agtattagca tagttgatta ttctacactt gaactagaaa aagaaatagt
     3121 attagaagat aatatatatc cacaccattt ttgcatagaa aaagaaaaaa atttaatata
     3181 catacctagt tcaagtaatg ggatactcta tgtcttagat ttaagtaatg ataaaataat
     3241 tgatactgtc tctataggag gaagtcttag tcaagttgta cttagcgata atgaattgtt
     3301 tgtggcaaat gaagattcta atagtatata tgtactagat aaaaacacat taaatccaat
     3361 aggaattatt ggagttgata atatgccaca tggatttgac tttgatagag aaagcaaaaa
     3421 gttatatgta ccgtgtataa actcgatagt atgtatagat acaattaata aaaatataca
     3481 aaagaaaata aatatggact ttagagcttg gcatatagaa cttgataaac aaaagaaaga
     3541 aatgtatata tcaacacttg atggaaagct tataataata gatgaagtaa gcatggatat
     3601 aaaaaaggta ttatatgaat ttttattacc agtagaaata agatttaatt atagtggcaa
     3661 aaaagtttat gttgctgatt tgggttataa taatgtaaga attttagatt atacaacgag
     3721 tagatacatt ggaaatattg aaataaatgg gattccccaa ggattagaaa tatctaaaga
     3781 tgaaaagtta ctatttgtat cagatacaca agaaaattca gtaaaagttt atgaaactgc
     3841 aaataacaaa ttaataaaag aaatcaaggt aggaaaagag cctacaacta taatttgttt
     3901 gtaggcttta atgtatgtct cttataagta aatcgataac ttcggcatac atataagatg
     3961 cattattttt ccagttattg caaataagtt ttgcttgttt ctctgatgaa acatttagat
     4021 ttaaatctat taagttagac tgattttcta tgactctaag gttgacaata aattcattat
     4081 cactttgttt tacaaaacta gactttactt gagtatctgc tagtagattt tctttgttag
     4141 aatctatata cttgtctatt ttttcagtaa cactagtagg tattcgatta aagaagtatt
     4201 ctagactttc tacgcctctt tgagtaagag cataatattc tctgtcagag tctttatatg
     4261 tagtcaaaaa cttagattcc ataagctgag ataaaagctg ttgtaatgaa aaataattca
     4321 tcatctcagt ctctaatact acttgagtta tttgagaatt agttaaatcc attttaattt
     4381 tttctaatat atataaaatt aaaagtttgt gataggctaa ttcttcagac gagttttcaa
     4441 acataaatat catcctccgt caaactattt ctatatataa tatattaaac taatttgtac
     4501 aaaattaaaa gaacaatttg tattgtatta ttaatcttta ataattcata taaaaacaat
     4561 tttataaata aatatagaaa aacagggctg ctaattagca gccctgttga tacccaggtg
     4621 tcaaaattta ctatttattt tccagccatt tgtctttcag ccatttcaac taatttctta
     4681 gtcatatatc caccaacata tccattttct ctagctgtta agttaccttt gtctatgttt
     4741 tcatagttag ataaacctat ttcgttagct atttctaatt tcatttggtt taaagcagct
     4801 tttgcttctg gaactactgt tctgtttgaa tttgacatag taaatttcct cctcaaataa
     4861 ttagtttatg atgtctaaca acacttttat ttatgtgatg ttaatactaa tttctccaaa
     4921 ataaaaataa tatatacaga aaaataaagg taaaaatgta aaaaatataa aaaaattaaa
     4981 taaatgagta ttttagagag tttaattagg tcaatatagg ttttattttt ttagttattg
     5041 tcttataaat taaatattac agtacttttt tgagctgaaa aaaaataaat tttaaatata
     5101 gaagaaatta tttcaaaggg ggaatagtat gaaaagagaa gttaaaagga ctaaagcttt
     5161 gatatatagt gttttatttt tttcattatt attagtgtta atatttgttt ttgtttatgg
     5221 aataaaatac atatgttcta aatctgacaa ttcaaaaatg cctatatata aagttgatac
     5281 aaatgagaaa aaaatagctt tgagttttga tgtagcatgg ggaactgata atatggatga
     5341 tattttaaaa attttagata aacataatgt aaaagcgacc ttctttttag ttggtagttg
     5401 ggtggatgat aatgaagaaa ttgtaaaagc tatagatgaa aaaggacatg aaattggaaa
     5461 tcattcaaat actcatgcca atttaaagga aatatcaaaa gaagacataa caaaagagat
     5521 agaaactaca tcagaaaaaa tatataatat aacaggaaaa aggactaatt tatttagacc
     5581 tccttttggg gacgtaaaca ataaagctat ggacatttgt agtgatttag gttataaagt
     5641 aattaagtgg gatgtagatt ctatagactg gaaggagctt ggaccaaatc atgtaattga
     5701 aaaagtaata aaagaatctc aacctggttc aatagtttta ttccatgcta atataaatga
     5761 tgtagataat tatttggata ctataataag tcgactaaaa aaagatggat acagtctagt
     5821 caaaatatct gatttgttgt ataaagataa ttatgtagtt gattccaatg gagtgcaaaa
     5881 aactaagaat taataagtaa taaatgtata ttttaagtaa agttgtgata aattatatag
     5941 tatatgttag aaaagtgtcg ataaaaagac ggtgtctatt ttttgacact ttttatacat
     6001 gtatgcaata tcaataatta tagattaaat tgattaaaaa agtgtctaat aattgacttt
     6061 tttttgatgg gtttaaaaat ttagaagaat taatgaatgc tgtaagacag tatttccaaa
     6121 gggtataagt ttgtttaaaa gttggcatag aaattgcttt gttaataagc gatatgttct
     6181 atagaaataa acaatatgtt aagaccttat aatagaaaaa tagcattaac attatttgaa
     6241 cagcttataa aaaaattaat atacttaagg gggcgtacta gttgaacaaa ctatattcta
     6301 ttttattaaa acaacacgtt ggtggtccag ataagccagt agtaagtgtt ggagatgtag
     6361 taaaaaaagg aactctaatc gcagaaccaa ctggattagg ggcaaatatt tatgccagtg
     6421 ttagtggaaa aataagtgaa ataaatgacc aagcgatagt aattgaagct gatgaagtac
     6481 aagaagatac ttttgaacca ttaaaaggag aaggtatact tgacttaatt aaagaagctg
     6541 gagtagtagg aatgggtgga gcaggattcc ctactcatgt aaaattaaac atagatttaa
     6601 atggtggaac aatattagca aatgcagctg aatgtgaacc tttattagct cataatataa
     6661 aagaaataga agaaagacca gaaatagttt atcaaggtat aaaatatgct atggaagtta
     6721 ctaatgctgg aaaaggtatg ctagcaataa aaagtaagca tccaaaagca atagaagctt
     6781 tcaaaaaagt aataaagcca ggagacaaca tagaagttgc agaactagtt gatatgtacc
     6841 caatgggaga agagagagca atagtaagag atgttctagg aaaattactt gagccaactc
     6901 aattaccttc agaggctaat gcagtagtaa taaacgtaga aacactaact agaatagtag
     6961 aggctgttga gcaaaaaaga ccagttatat ctaaaaatat aactgtagtt ggtcaattaa
     7021 acagtggaaa agaatctata gtgtttgaag atgtgccaat tggaacaact gtcggagaat
     7081 taattgaaag agctggtgga ataaaaggtg aatatggtga aataatccta ggaggacctt
     7141 tcactggtaa agctactact ttagatgctc caataactaa aactagtggt ggtataatag
     7201 ttactatgcc atttgttaat gaaaagagaa aaatgggtct tttagtttgt gcatgtggac
     7261 ctaatgaaga aagaatgaga gatatagcaa ctaaaatggg agttactgat atagtatcag
     7321 ttcaaaaatg taaacaagct caagaaatta aaggtgcatt aaaatgtgaa aatccaggac
     7381 actgtccagg acaagctcaa aaatgtattg aatttaagaa agctggagca gaagttatat
     7441 taataggaaa ctgtactgac tgtagtaaca cagtaatggg ttctgcacca aaattaaaat
     7501 taggtgtata tcatattact gaccatgtaa tgagaacagt taatcaccca ttaataagaa
     7561 gaataaaagg tgacgtaaga ttaaaaataa aataatagat aaatagaagt tagacatctt
     7621 tagaagtaaa acttaaaagt tacttctaag gatgtttttt aatgtatttt gagggcaata
     7681 tatatattgt aaaataaatg gaaaaaatag acaaaatatg ctagatattg tataatgata
     7741 acaatagcta ttacaattaa tattggacaa aaataatgat actcaagtat gtggtttgta
     7801 ttaatatgca tattatatta agtcaactat ccgatagagt aaaaggtttt tgtgatattt
     7861 gaagatactc tatagtatct tttttattat aaaaactaat ttttgtcttt tattagataa
     7921 gtatctagga tactaattta tattttattg agttgttaaa aaagtgcact taaaaagtta
     7981 aaaaagaaaa attaaaaacc tatttataga aactgtgaag tatatcttaa acctgggcac
     8041 ttaaaagata tatggagtta gtagtgcaac ctgctataaa tataaatagg agtaactttt
     8101 aattgtcaaa aatatataaa ataaatacat aaataagtaa ttaatagaag atagatataa
     8161 atatattttt gaaatgctcc ctgcattcat aacgagtgta gagtggcaga tatctgccca
     8221 aaactccttt aattgctgga agttcctaaa gctaactaaa ccacaacata atcatgaaat
     8281 aaggataagt gtgatagagt gtgcatttaa taagcacttg aggttacgaa agtagaaaaa
     8341 attagttaga tagcataagg ttaaatccta agtgccttga aaatggataa tcagcaggta
     8401 agcttcgaaa agaagaaact tcaacgacta gagagaaatc tcgtacctac aagtgtgggg
     8461 aaatggggag tacctaattt atggttaggt aatgatatag tctgtgctta atagaaatat
     8521 taagaagttc ataggagaac tggttaggag taacgaccct aattgaacac actaaagatg
     8581 tattattgaa taagattcat ataatattta ataattttaa ttatattaag tgaatacaat
     8641 atatgttttt agtatcagga gaattttgaa aacaaaaatt aaaaaatcaa gtataatcag
     8701 tttagtaatt gcttttagta tggtatttac tgcatttaca ccaatagtat cttatgctga
     8761 cgaagtgact agcaatgata caatacttaa tggagaagaa caatcaaatg gtcagacatc
     8821 agatgtagag aaaccatcag acggtcaggt accagatggg gagaaaccat cagacagtca
     8881 agtaccagat gtagagaaac catcagacgg tcaggtacca gatggggaga aaccatcaga
     8941 cagtcaagta ccagatgggg agaaaccatc agacggtcag gtaccagatg gggagaaacc
     9001 atcagatggt cagataccag atggggagaa accatcagat ggtcagatac cagatggaga
     9061 gaaaccatca gatggtcaga taccagatgg ggagaaacca tcagatggtc agatgccaga
     9121 tggagagaag acatcagata gtcagacgcc agatgtagag aaaccatcag atggtcagat
     9181 gccagatggg gagaaaccat tagatgagca aactccagaa gaagaaaaac cattggaaga
     9241 agaaatagtt atagaggaaa tgagtttaaa acaagatatt gataaaattc ttgatatgac
     9301 tttatctcaa ataaataaaa tagtatataa cttttgggaa gatgaagaag atgtaaaggc
     9361 agatgaacaa tcagaaatta accaagtttt tacttcagaa gactcattta ttagcttatg
     9421 gtatgacaaa aaagcaaaag taaaaaattc ttgtttacta aaagaaatag atggttcaga
     9481 tagaccttat catgatttaa gatttgatga tattacaaag actttaactt ttgactatgt
     9541 aataaagggt cttgtaggag caagctcaaa agacgacaaa tatgtaatag aaggtgaaga
     9601 tggagagcaa actgcatttt gttacaataa tcatttaaga ccaccaagta gtaatggaaa
     9661 gagtccatat ttaccagcag aagattttaa tggtcaagaa aaccaaaatg aagaagcagt
     9721 taaatctata ctatatgcag gttctgaatt tgatggattt ggatataagc aacaatttaa
     9781 tttaggtgga gaagaaaatg aattgatgac ttactcagct actcaaagtg caatttggat
     9841 tattcttgga caaatggatg aacaagaaag acttaagcag tatcaaggtt ctataaacct
     9901 ttgtgataaa cttatagaaa gagcaaaaac tgaagaggaa agagctgagt atcagaagaa
     9961 gaaagaagta gcgataaata taaaagctta tttagaagca ttgttaaaag caggtcgtga
    10021 agagttaaag ccaaataata caggaaaacc tagtttgagt aatggtttaa ctaagattaa
    10081 ctttgaaaaa aatgaagatg gtacttatga aacagaagct gtagccttag taggttatag
    10141 tggtgtagta aagttaaaac taccagatgg agtaactgct tatgatggag atggtaatat
    10201 aataggtaca ggcgaagtag aaatttcaac gcaacagaaa tttaaactta agagtgttgg
    10261 aaaaccagat gccaaagcta atatttctgc tgtatcttat gattatattt ttccaaaagc
    10321 tattcaatat tataaggcag tgcttgattt aggacaaaaa gaccattcat cttcattacc
    10381 atctagcaag caaaatttat taagttatac aatagagaaa aagaatggtc aagaagttaa
    10441 ctttaatata ggtttaccaa cagatgatga tgatgttgta aatccaccag tgccaccaat
    10501 agatgatgat gttgtaaatc caccggtgcc accaacagat gatacaaatg gacataagcc
    10561 aaaaccatca ccaccaatag atgatacagt aataaatcca ccagtaccac caatggatga
    10621 tacaataata aatccaccag taccaccaac ggaggatgca gtgttaaatc caccagtgcc
    10681 accaatggag gatgcagtgc taaatccacc agtgccacca acagaggata cagtgttaaa
    10741 tccaccagta ccatcagtaa gtgatacagt ggaaaaaact ccagaactat caagagatga
    10801 tacaataata aaatcaccaa aaacaggtga tgaaactcag ctaatgtcat atgtatttat
    10861 tagtgtcatt gcaatttgtg gattagcgta tcaatgtaaa ataaaaagaa attaatctag
    10921 attattatta agtttaaaat aaaaagtctc aaattgattt ataagtcatt ttggggcttt
    10981 tttatgtaaa tataatatgc aaatatagtt tgtttaaaaa tatctatttt aattatattc
    11041 ttaaatttat tattggatac aggcattcat taattgtttg atgaatagaa aaatgttttg
    11101 aaggtgaaaa tagtattgaa aaaataatat actaagggta taattcattt gatttcattt
    11161 gtataaattt aattataaat tttaaagtga ttatataaat ttaaatgcta attacttaat
    11221 aaattttaat aataattatt taataaataa ttattataat atgctagaat aaatatatat
    11281 aaataagttt tgatgaggta ctactataaa ggggggactt tatgttttcg ataccagaag
    11341 taaaaaaagt agaagaggta atggatacaa aatttacaac tatagacgaa gacacaagaa
    11401 ttgaagatgc aataaaagaa atgataaaaa gcaacacaaa aactctaatg gtaatagatt
    11461 catctgacca attaaaaggc attatatcca tgacggatat acataatctt tatgagatgc
    11521 ataaaaagta tgaaggtcaa ccagtaaaac ttataatgaa gaaggatgta atatatgtca
    11581 acgaaggttt aaccttagat gaatgtagag atataatgat attaaaaaat atagggattc
    11641 ttcctgttct tagagataat aaaattattg gagttctaaa acaagagcac attagggact
    11701 atctatatat gcatttagaa gattatggat taactttgaa gtatattata ggtcaaatta
    11761 aagaaggaat ttgtgctata aataacgaag gtgttgttat cttgtggaat aagtttatgg
    11821 aggaaaggta tgatataaag tctgaagata tagttggtcg accgatgaat gaatttttgg
    11881 aaaatactat ttcagaaaaa gtactaaata gtaaagttgg aatgagtgac ttgtatttta
    11941 cagataaaaa agaaaatatg tatgcattag ttcatgcaaa tcctatattt tataaagaag
    12001 aatttatcgg tgttgtatgt acagaagttg atgttacaga agctaagata ttagctcttg
    12061 aacttgaaaa agtaaatgat acattaaaat atctaaagaa cgaagtcaaa aatttatcta
    12121 aaggtagttt tgataagatt ttaggtaaaa gttataaatt ggaaaaatcg aaagcgattg
    12181 caaaacaagt ggctagaaca aatagtagta tatttatttg gggcgaaagt ggtacaggta
    12241 aagaagtatt tgcaagagct attcatgatt atagtgagag aaaagggcaa tttatacctg
    12301 ttaactgtag tgccatacca aatgagttat ttgaaagtga gttttttggg tatgaatcag
    12361 gtgcatttac aggagcaagt aaaaagggtc gaataggtat atttgaactt gcaaaagatg
    12421 gaactgtatt tttagatgaa attgccgatt tacctcttag tatgcaagca aagttgctta
    12481 gagtattaca ggaaaaagaa ataagaagag ttggtggaga taccacaata aaaataaatc
    12541 ctagaataat atcagctacc aataaagatt tgagtaaaat ggtaaaggca gaaaaattta
    12601 gagaagattt atactataga ttaaatgttg ttgaaataaa gattcctcca cttagagaga
    12661 gaaaagaaga cataggatta ttggttcata gctttttaga ggagatatgt aaacaaaata
    12721 ataagcctgt tcttacaatt agcaaagatg taatagatat atttcagaat tatagatgga
    12781 aaggtaatat tagagaatta aaaaatacga ttgaaaatat tgttgtattg tcacaaaatt
    12841 ctaaaataga tgtggatgat gtaccaagtt atatgatgga ttctacaaat aatagtactg
    12901 aagaagaaga gtatccttta gatttaacga aggcaactca aaaaattgaa ataaagaata
    12961 taaccaaggc acttaaaatg tctaatggaa ataaagctaa agcagctaag atattaaata
    13021 tacccagaac aactttgtat tataagatag accaatacaa aatagatgtg tctaaaatat
    13081 gacacatgac taaattttga caaaatgata aactttaatt taaaacctag taaagccaac
    13141 acttgtataa gtgttgtgta tatagatgtg ttaaaaaaaa tgaaaaagtg ttgattaatt
    13201 gacacttttt ttgtttgaga aaatgtttac aaatacaaaa aataacatat tttaaataaa
    13261 tatttatata atatttggct aaaaatagcg atagatgaag aatctattat agaaaaaatc
    13321 tttttgttaa taagttggca taggaattgc ttataatata aagtgacttt aagtgagaaa
    13381 aaaataatat taatcataac aaattatgta ggttttaatt tacttaattt ctcagttaag
    13441 gggttacctg ttgaggaatt gagatttaaa ataataaata agaaaataat gtaaggaggt
    13501 attttatact atgtcaataa ctttagaaac agctcaagcc catgcaaatg acccagcagt
    13561 ttgttgttgt agatttgaag cgggaacaat tatagcgcca gaaaacttag aagatccagc
    13621 aatatttgca gacttagagg attctggatt attaacaata ccagaaaatg gattaactat
    13681 aggtcaagta ctaggagcta agttaaaaga aactttagat gcactttccc caatgactac
    13741 agataacgta gaaggataca aagcaggaga ggctaaagaa gaagtagtag aagaaacagt
    13801 agaagaagca gctccagtat cagaagcagc agtagttcca gtaagcacag gagttgcagg
    13861 tgaaacagtt aaaatacaca taggtgaagg taagaacata agcttagaga tacctttatc
    13921 agtagctggt caagcaggag ttgctgctcc agtagcaaac gttgctgctc cagtggcaag
    13981 tgcagcagca gaagtagctc caaaagttga agaaaagaaa cttttaagaa gcttaactaa
    14041 aaaacacttt aaaatagata aagttgaatt tgctgatgaa actaaaatag aaggaactac
    14101 tttatacatc agaaacgcag aagaaatatg taaagaagct aatgaaactc aagagttagt
    14161 tgtagatatg aagttagaaa taataactcc tgataaatat gaaacttaca gtgaagctgt
    14221 attagatata caaccaatcg ctactaaaga agaaggcgaa ttaggttcag gtataactag
    14281 agttatagat ggagctgtaa tggtattaac tggtacagat gaagatggag ttcaaatagg
    14341 tgaatttggt tcttcagaag gtgagttaaa tactactata atgtggggta gaccaggtgc
    14401 tgctgacaaa ggtgaaatat tcatcaaagg tcaagtaaca ataaaagcag gaactaacat
    14461 ggaaagacca ggacctttag ctgctcaccg tgcatttgac tatgtaactc aagaaataag
    14521 agaagcatta aagaaagttg acaactcttt agtagttgat gaagaagtaa tagagcaata
    14581 cagaagagaa ggtaaaaaga aagttgttgt tataaaagaa ataatgggac aaggtgcaat
    14641 gcatgataac ctaatattac cagttgagcc agttggtaca ttaggagctc aaccaaacgt
    14701 tgacttagga aacatgccag ttgtattatc tccacttgaa gtattagatg gtggtatcca
    14761 tgcattaact tgtataggac ctgcatcaaa agaaatgtca agacattact ggagagagcc
    14821 attagtaata agagctatgg aagacgaaga aatagattta gtaggtgttg tatttgttgg
    14881 ttctccacaa gtaaatgctg agaaattcta tgtatctaag agattaggta tgttagttga
    14941 agctatggaa gttgatggag ctgtagtaac tactgaaggt ttcggaaaca accatataga
    15001 tttcgcatct cacatagagc aaataggtat gagaggtata ccagtagttg gtgtaagttt
    15061 ctcagctgtt caaggtgctc tagttgttgg taataaatac atgactcaca tggtagacaa
    15121 caataagtct aagcaaggta tagagaatga aatattatct aacaacactt tagctccaga
    15181 agatgctgtt agaataatgg ctatgcttaa aaatgctata gaaggtgtag aagttaaagc
    15241 tcctgaaaga aaatggaatc caaatgttaa attaaataac atagaagcta tagaaaaagt
    15301 tacaggagaa aaaatagtat tagaagagaa tgagcaatct ctaccaatga gtaagaagag
    15361 aagagaaata tacgaaaaag acgaaaacta aaatttagat actaactaag atttagacaa
    15421 taacataaat ttagatccaa gtttaaaaca gtatagagag gtagaattat aatggatagg
    15481 ttaaaatata tctcatcaga gactttttat gaaggtatta tagttgacat caaaggcggt
    15541 ggagtgacta tagacctaaa aggtagactt ggacaattta aaatacctaa tagaatgctt
    15601 ataactgact acgaacttaa gataggtcaa gaagttggat tcatgctaag ctatcctgag
    15661 gtattaagtc cagagcctaa tcaagagtat gtagaaaata ttaggagaga aaaagaaaaa
    15721 caagcagaaa tgcaatcaaa acaagaagaa aaataataaa taatcgtttg aaaatagaag
    15781 ggagaggaaa tatatgagcc ttacaacagt acaaggactt caatctgaaa tattcgttcc
    15841 aataacacct cctccagttt ggactcctgt aactaaagaa ttaaaagata tgactatagc
    15901 tttagctaca gcagctggtg ttcatttaaa atctgacaag agatttaatc tagcaggaga
    15961 tactacattt agagctatac ctaatacagc tacagttgat gaaatgatgg tatcacatgg
    16021 tggatatgac aatggagatg taaacaaaga tataaactgt atgttcccta tagatagatt
    16081 acatgaatta gctgcagaag gatttatcaa aggagtagct cctatgcact atgcattcat
    16141 gggtggtgga ggaaaccaac atgtcttcac tgaagaaact ggtcctgcta tcgctgctaa
    16201 acttaaggaa gagggagtag acggtgtagt tatgacagct ggctgaggta cttgccatag
    16261 aactgccgtg atcgtgcaga gagcaataga ggaagctgga atacctacaa taataatagc
    16321 agctcttcct ccagtagtta gacaaaacgg aactcctaga gcagttgctc cattagttcc
    16381 aatgggtgct aatgctggtg aaccacataa tatagaaatg caaacacata tattaagaga
    16441 tacattagag caattagttg caataccatc tgctggtaag atagttccat taccatacga
    16501 atataaagct cacgtttaaa atgtaattta tatttgaaaa tatagaaccc ttctcctaca
    16561 cggttaggag aggggtttta agaacaaagg tggatattat ggaagaaaaa ataatgagaa
    16621 gacttgttat aaaaccgttt catatgaatg aagttaattt cggttcaaaa acttctataa
    16681 agaaagatgt acttacaata gatttatcaa gtatagatga aataaaagaa agagaagagt
    16741 taataacaga cataaaagta gacattataa aacctggaga ttatgacaga gaaattaata
    16801 ctattatgga cattatacca atatcaacaa aagttttagg cagactggga gagggtatta
    16861 cacatacttt aacgggtgta tatgtaatgt taactggtgc agatgaagat ggaaatcaaa
    16921 tgcatgaatt tggttcttca gaaggaattt tgaaagacca aatggtattt gggagatatg
    16981 gaactccatc agttgaagat tatataatcc atgtagatgt aactttaaag ggaggtttac
    17041 cttttgaaag aacacttcca cttgcagcat tcagagcatg tgatgatttt atacaagaaa
    17101 taagagcgtc tttgaaaatg gaagacggaa gaaatgctac tcaagttcgt gaatattttg
    17161 acaaaattcg accaaatgca aaaaaggttg tcatagtaaa acaaatagca ggtcaaggtg
    17221 ctatgtatga caatcagtta ttctcaaagg aacctagtgg atttgaagga ggaacatcaa
    17281 ttatagatat gggaaatgta cctatgatta tatctcctaa tgaatacaga gatggtgccc
    17341 ttagagctat gacttaagag aggtggatat tatgggaata ggaccttcaa caaaagaaac
    17401 atctcttcat cactttagag acccactttt agacatagtt gaaagtgata aggatgtaga
    17461 tttacttgga gtaatagtag taggaactcc agatggaaat gaaaataaaa cctttgtggg
    17521 acaaagaacg gccgcttggc tggaagccat gagagtagat ggagctatag tttcatcaga
    17581 tggttgggga aactcacatg ttgactacgc taacacattt gaggaaatag gaaaaagaga
    17641 tatacctgta gttggagtta catttaatgg gactcaagct aagtttgttg taagcaatca
    17701 atatatggat accatagttg atatgaacaa atcaaaagaa ggtattgaga cagaagtagt
    17761 tggagaaaac aacacaaatg aaatagatgc taaaaaagct ttggcatttt taaaacttaa
    17821 aatgagaaaa catggataaa aaatttaagt aagggaatga gttttgtggg aatttctaca
    17881 tcaatgaaaa acacatcact tcatatattt agagacccgt tactagattt gatagataat
    17941 gattctgaca tagacttgtt aggagtggtt gtagttggga catcagagca caatgaatgg
    18001 aaaacatttt tagcaactag acttggaaga tggattgaat cattgcgacc tgatggagtg
    18061 attataactt tagatatggc aggaaaccag cacattgatt ttacaaatgc tatagcagag
    18121 tttgtaaaat cagatatacc tacagtaggt cttactatta tgggagcaga tggattagta
    18181 attaccaatc catagttgga taaagctacc ataattgatt ataaaaagac aacaggctac
    18241 atagaaacag aagtagttgg agacaatcac atggatgaag ttgatgttaa aaaagcattg
    18301 gctttcctaa aattaaaaat gcgtaaagac gcaaaataaa cctaaggggg aatttgatat
    18361 gaaatttagc agaagtatac aagctataga ctctcataca gcaggtgaag caactagaat
    18421 agttgtaggt ggaataccta acataaaagg aaattctatg cctgagaaaa aagaatattt
    18481 agaggaaaat ctagattatt taagaactgc tataatgtta gagccaagag gacataatga
    18541 tatgtttggt tctgtaatga ctcaaccttg ttgcccagat gctgactttg gaataatctt
    18601 catggatggt ggcggatacc ttaacatgtg tggccatggt acaataggag ctatgacagc
    18661 agctatagaa acaggtgtag ttccagcagt agagcctgta actcatgtag ttatggaagc
    18721 tccagcagga ataataagag gagacgttac agttgtagat ggaaaagcta aagaagtatc
    18781 attcttaaac gtaccagctt tcttatataa agaaggtgtt gaagttgact taccaggtgt
    18841 tggaactgtt aaatttgaca tatcatttgg tggaagcttc tttgctataa tacatgcaag
    18901 tcaattaggt ttaaaaatcg aacctcaaaa tgctggtaaa ttaactgaac tagctatgaa
    18961 acttagagat ataataaatg agaaaataga aatacaacat ccaactttag ctcatataaa
    19021 aactgtagac ttagttgaaa tatatgatga gccaactcat ccagaagcta cttacaaaaa
    19081 tgtagttata tttggtcaag gtcaagttga cagatctcca tgtggaactg gaacaagtgc
    19141 taaattagct actttacatg ctaaaggtga attaaaagta ggagaaaaat tcgtatatga
    19201 aagtatatta ggaactttat tcaaaggtga aatagttgaa gaaactaaag ttgcagattt
    19261 caatgctgta gtacctaaaa taactggttc tgcttatata actggattta atcattttgt
    19321 aatagatgaa gaagacccac ttaaacatgg atttattctt aaataagtaa taaataaatt
    19381 aggaaattaa aatagaatag tagccacttg tcggttgcta ttctatagct tttaggctat
    19441 aagattcaga atatatgaaa aaataaaaaa ataggaggat ggattatggt agcaatctta
    19501 aaggcattat atgtagtatt cgcagcaatc tttgcagttg tgtttggtaa agacgtagct
    19561 aaagcaaaca aagaggggaa actagaagaa caaagtactc caaaagttgc tgtaacagga
    19621 tttataacag acttctttga tacattagga atagggtcat ttgctccaac aatagcaatg
    19681 tcaaaggctt taaagttaaa tataccagat aaaaaaatgc ctggtacatt aaacgtagca
    19741 catactattc cagttgttac agaagcattc atatttacat caatcatacc agttgatggt
    19801 gttactttag tatctatggt tgtggcagca gcagttggtt catatatagg tgcaggaata
    19861 atagctaaga tggacgagag aaaaatacaa cttgttatgg gtgtaacttt agcattaaca
    19921 gcaatattaa tgttattagg tcatccttgg attaacgtat taccaggtgg aggaaatgaa
    19981 ttaggtctta ctggtgttaa attagtaata ggtgtaatag gtaactttat actaggagct
    20041 ttaatgacag ctggtatagg tttatatgct ccaggtatgg caatggttta tttcttagga
    20101 atgtctgcaa aagttgcatt cccaatagtt atgggttctt gtgcattatt aatgccagtt
    20161 gcaagtatga aattcataaa agaagatgca tatactaaaa aagcatcagt tataatagct
    20221 atatgtggtt taataggagt tttcgtagct gcatatatag taaaaactct accaatggat
    20281 atattaaaag cattagtaat agtagttata gcttatactt ctgctacaat gataatggct
    20341 gcaaataaaa acaaaaagac tgcttagtta aagactactt agtgtttatt aaatattaca
    20401 gctaataata aagattataa actgctttaa aatattgaat taatatttta gggcagtttt
    20461 ttatttacta aattaatata aagcaattaa catgccaatt atgtaatata tatag
//
LOCUS       DAEPHU010000073        20227 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 01A10CD0081
            SAMN05941466-rid12468953.denovo.073, whole genome shotgun sequence.
ACCESSION   DAEPHU010000073 DAEPHU010000000
VERSION     DAEPHU010000073.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941466
            Sequence Read Archive: SRR6291087
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 20227)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20227)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068158.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 22:43:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,892
            CDSs (total)                      :: 3,805
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 87
            rRNAs                             :: 8, 1, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 55
            CDSs (without protein)            :: 55
            Pseudo Genes (ambiguous residues) :: 0 of 55
            Pseudo Genes (frameshifted)       :: 21 of 55
            Pseudo Genes (incomplete)         :: 28 of 55
            Pseudo Genes (internal stop)      :: 16 of 55
            Pseudo Genes (multiple problems)  :: 8 of 55
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20227
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941466-rid12468953.denovo.073"
                     /strain="01A10CD0081"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     misc_binding    346..577
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            685..2166
                     /locus_tag="KR231_002919"
     CDS             685..2166
                     /locus_tag="KR231_002919"
                     /EC_number="4.2.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine synthase"
                     /protein_id="HBH0005279.1"
                     /translation="MYYSSTRGTEEKVTASQAIIKGISNDGGLYVPSEFPNVKNELIN
                     LVNLTYSQIAFFVLSKFLCDFTEDEIKNCIENAYDEKFDCSSIAPLNKVNDTYFLELY
                     HGPTLAFKDMALTIMPHLLKTSIKKDNLEKDVVILTATSGDTGKAALEGFKDIDKIKI
                     IVFFPEDGVSPVQKLQMKTQTGKNTYVVGIKGNFDDAQSGVKKIFSDKEFNQKLLDNN
                     YILSSANSINIGRLLPQVAYYFYSYMKLVSNSDINLNDKINFVVPTGNFGNILAGYYA
                     KQMGLPINKLICASNDNNVLYDFFKTGVYDKNRTLKLTTSPSMDILISSNLERLLFEI
                     SNRNTDIVNKLLSDLSDKGVYKISDDMEKNLASFYGEYSNEEEVKSTINNVFKNYNYL
                     IDTHTAVAYNCYEKYKKETSDNTKTVIVSTASPFKFSEDVLKSIDCDFKDLDDFAIID
                     RLSSISKIDIPKPIKNLKNAEILHKDIYEKDELKLAIKKFLKV"
     gene            2176..3069
                     /locus_tag="KR231_002920"
     CDS             2176..3069
                     /locus_tag="KR231_002920"
                     /EC_number="2.7.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine kinase"
                     /protein_id="HBH0005280.1"
                     /translation="MLEIIVPATSANIGPGFDCLGIALNIYNKFYVEEIESGLEIEGC
                     EDAYKNENNLVYTSMKYFFDRVKPEKIPAGIKIKIQSEVPICRGLGSSASCIVAGVIA
                     ANALSGANLDKNQLLNIASEIEGHPDNVAPAILGNMIVSVTDNENIHYDIIKIPEELK
                     FCAMIPNFKLSTEKARGVLPKEIPYSDGVFNVSRVALLISALLNKNFDLLKVACQDKL
                     HQDYRGTLIENYNDIVEKSEQLNSIGVFLSGAGPTIMSLIKENDDSFVDNMKNYLQKL
                     KSDWEIKELCCDSNGAVLNII"
     gene            3193..4254
                     /locus_tag="KR231_002921"
     CDS             3193..4254
                     /locus_tag="KR231_002921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015617764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitronate monooxygenase"
                     /protein_id="HBH0005281.1"
                     /translation="MIIKELIIRDLVAKVPIIQGGMGVGISRSSLAGAVAKLGGVGVI
                     SGVQIGYDEEDFETNTINANLRAIKKHISKAKEISNGGIIGINFMVAMKEYETYVKEA
                     VKAGVDLIISGAGLPNKLPSLVKGSNVKIAPIVSTAKAANVILKMWDRKEKTTADLIV
                     VEGPKAGGHLGYSNEELDNIDSIDYDKEFVEILKVANTYGEKFGRNIPVVAAGGITSS
                     SDVKKYIDMGASGVQVGTRFVATYECDAHENFKMAYINASEEDVHIVKSPVGLPGRAI
                     RNKFIEEVKINRPEIKKCYNCLIPCNPKETPYCISQALINAVKGDVENSLLFCGNDAY
                     KIDKLSTVEDVINELISEL"
     gene            complement(4409..4921)
                     /locus_tag="KR231_002922"
     CDS             complement(4409..4921)
                     /locus_tag="KR231_002922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavin reductase family protein"
                     /protein_id="HBH0005282.1"
                     /translation="MSDFKEILAEEIKNNPFGLIGKDWTLITAENEGKVNTMTASWGG
                     LGVMWGKDVAFVVIRPQRYTKEFIDNTDKFSLTFFDEDFRKELSYCGKVSGREEDKIS
                     QIGFNIEHLNDTPYFKEAKMAIICKKMYSQKLEPQCFIAEGIDGRWYPQKDYHTLYIA
                     EITNVLVKED"
     gene            5441..6376
                     /locus_tag="KR231_002923"
     CDS             5441..6376
                     /locus_tag="KR231_002923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HBH0005283.1"
                     /translation="MIRYYKTIDSKLEKLSFFEDGCWINLVEPNHSEINEISNLLNID
                     VESIESALDEEERSRIDVEDNHTLILIDIPVDESDSNSSHYTTIPLGIILTEEAIVTV
                     CDAQTKILNDFIVGHIKDFFTFKKTRFLLQILHKNAAYYLHYLRKINKMTIIIEREIY
                     KSMKNKELVQLLELEKSLVYFSTSLKSNELVLNKMVRTAGIKKYPDDEDLLEDVIVEN
                     RQALDMAKIYGDILSRIMDAFSAIISNNQNNVMQILTVVTLIFSIPTIISGFFGMNVI
                     NMPFSNNPNGFWIILLITSIICIVITFFMSRNKLL"
     gene            complement(6468..8339)
                     /locus_tag="KR231_002924"
     CDS             complement(6468..8339)
                     /locus_tag="KR231_002924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sel1 repeat family protein"
                     /protein_id="HBH0005284.1"
                     /translation="MKNTKFSIKKIKNISNDPKVVHTKGALLEKMGKMESAIELYKSA
                     ALDNYVKSQYTLGNIYESKKQFKEAEKWYSMAYKSGSEDAAFDLGNMYYKLDGYEYAI
                     YWYEKIANLGYLQAQNNLGVCHFKMKDFVRCEKWLKTAADKNLGKACFNLGVLYTFLE
                     KDDEAYEYYKKGSVLLDDDAKYNLAILNGKKKDNKSTVSLYKQLYKSGHMKGCFNLGM
                     IMEINDNLEDAEKYYKKSADRDDVKSEYRLAYVYDRKEELGDAIYYYEKAIEKNHTLS
                     KYRLANLYNRENEIEKAKTYYKMAAEDDITEAKNNLAGIYFEEKDYENAIKYYEDAIA
                     VGCKSSLENLGDLYYQNQDIEKAISYYSRIPNNVSCQIKLGNIYEDLNNIEEAISWYK
                     KASENGDTRSSYRLGCIYESLGNTKNARKYFEMASSKNHMNARIHLGRIYFREGKLEE
                     SKMMFDTPANENNVYAQHMVGLIYDMFYKDYVNSKFWYEKARAQGCVESIYNLGQIYL
                     KLNDDAEAEKYYKEGIKYGSKKCEYMLAGLYYKKSLDMYISLANEEYDNCEEIVEGFP
                     NLNIDFDEVLIPPFKLQEEVIDEEEYVPIYILNIKESLDSMLEGLETEMIIDEEHDS"
     gene            8529..9455
                     /locus_tag="KR231_002925"
     CDS             8529..9455
                     /locus_tag="KR231_002925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AEC family transporter"
                     /protein_id="HBH0005285.1"
                     /translation="MNFSNIFIQVAVLFIIILVGYFVRKFNLLDDHCTSKLSTLTMTV
                     FLPSMIISSMQINFDSKMIQKILLLLFTSLIMYIVSIIIAFLLKYILKCNDKKDLGIY
                     QYIVVFSNVAFMGYPVIEAVLGHEAIFYTAIFNLPFNLFSFTLGIYLLSKGSTSRGFS
                     IKSLISPATIAIVIGLFLFVTGLRLPQFINEPLEMLGSITTPISMIIIGSLLANSSAL
                     DCFVNKKLYIVTFIRLLVLPVIVYFILKGWINDKMILAIPVVISSMPAAANTAIMANQ
                     YDSNITLASQCVFFTTLFSVISIPFISILLLS"
     gene            9594..9740
                     /locus_tag="KR231_002926"
     CDS             9594..9740
                     /locus_tag="KR231_002926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0005286.1"
                     /translation="MDMDLLFKIVFAIVAIGVSVKIIKTVASLAFKIALILLIILFVY
                     RMFL"
     gene            complement(9845..10369)
                     /locus_tag="KR231_002927"
     CDS             complement(9845..10369)
                     /locus_tag="KR231_002927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBH0005287.1"
                     /translation="MSKPIDITIRPIRREDAQAFNEIRRTYSVMRNTLALMSDRVDKT
                     EAMLASLGENDYMFVAETNNNGEKDVIGFAGLHVNSSPRLRHSAEIGISVAENYQGRG
                     VGKKLMEQLLDIADNWIMLTRVGLEVIVDNEKGLNLYKKLGFEIEGTKKYAVIRDGKF
                     EDVYIMGRYNKNLI"
     gene            complement(10422..10646)
                     /locus_tag="KR231_002928"
     CDS             complement(10422..10646)
                     /locus_tag="KR231_002928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0005288.1"
                     /translation="MIIKLTKDNFNFRFKQYEGMFFHAEVVEGMESIRYKITKDKEGT
                     ELKEFGSTHIKDNMIYVPQVEAYIDLNSIK"
     gene            10843..11967
                     /locus_tag="KR231_002929"
     CDS             10843..11967
                     /locus_tag="KR231_002929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3810 domain-containing protein"
                     /protein_id="HBH0005289.1"
                     /translation="MSKKTKYFSLILFPIALLLNFIASKVPNIVEKYYSQFIDKIIVQ
                     ILSKVSGIFPFSLYEITMYIIVISIFLFLCCTLSTIFNKKKKLNIYLKNSILNILSIV
                     SIVYFLFVVLWGINYNRIPLETTLINNYNLKNNTSIQSKQYSVKELTKLYKFLVIKAN
                     ETRKLTLQDKNGIVKSNTDYNGVINRAQLGYDNILDILPGVSGSYSKPKYIISSNLMC
                     YTGITGIYFPFTGEANVNIAIPDLYIPCTVEHEMAHQRGFASEDEANFIAYLTSIKHP
                     NIDFNYSGYILALNYTASALSKVDYNAYVDISAGISDSVRRDLKNESEFWQKYEGKIN
                     EISNEFNNSYLKANSVTEGTQSYGKMVDLLLTYYELYPYN"
     gene            complement(12441..13265)
                     /locus_tag="KR231_002930"
     CDS             complement(12441..13265)
                     /locus_tag="KR231_002930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0005290.1"
                     /translation="MRYKKISSLPILVVALLITGTTTTFSLSTTNSEKTNVYLANTVS
                     TVTKKVSDIQSSKGLVYNENIPLFINNSKIQYDDTPYHWPSNVISLTNSSEKAIMDYE
                     ITCLAYDKNGKPLELYWDAQNVAADGEVGSVGFSPAGVDYGIVTGISPVSPKSYSHTY
                     RKMQQSPPQDIISMFEKQQGKAWVENWLKEWKQMEKEYAKQNAIAPGKNQNDAFLLFD
                     KWKQSTGEHGVKYIISCVKQVTFNDGSVWKNSAYENWLKSFQGKEVSNSVLENYYK"
     gene            complement(13613..14668)
                     /gene="ispG"
                     /locus_tag="KR231_002931"
                     /gene_synonym="gcpE"
     CDS             complement(13613..14668)
                     /gene="ispG"
                     /locus_tag="KR231_002931"
                     /gene_synonym="gcpE"
                     /EC_number="1.17.7.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin-dependent
                     (E)-4-hydroxy-3-methylbut-2-enyl-diphosphate synthase"
                     /protein_id="HBH0005291.1"
                     /translation="MSYERRKTREVSVGTVKIGGENPISIQSMTNTDTRDADATIAQI
                     KRLEEAGCDIVRVAVPDIKAAKNIAKIKSSVNIPIIADIHFDYKLALEAIEQGVDGIR
                     INPGNIGSIERVKMVVEKCKERNLKIRIGVNGGSLEKELLKKYGSATAEALVESAMGH
                     IKILEDLDFHNIVISLKSSDIYKTVDAYELISKKVDYPLHIGITESGSVHKGTIKSSI
                     GVGALLLKGIGDTVRISLTGDPVEEVIVGKQILRSLGLLNDKIKVISCPTCGRCNIDL
                     ISVVNEVEEKIGSMEKNITVAIMGCAVNGPGEAREADIGIAGGKGEGLLFKKGEIVRM
                     IDGNKLVDELLEEIEKL"
     gene            complement(14850..15854)
                     /gene="rseP"
                     /locus_tag="KR231_002932"
     CDS             complement(14850..15854)
                     /gene="rseP"
                     /locus_tag="KR231_002932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RIP metalloprotease RseP"
                     /protein_id="HBH0005292.1"
                     /translation="MTIIAALILFSIIVLIHELGHFIFAKRSGIKVNEFSIGMGPKIY
                     SVKKDTEYSIRALPIGGYVSMEGEDEEQISPNSFGNKSILQRFSTIVAGPIFNIILAA
                     ILLVPVFLYIGSPTTKLGKIMPDTPAQAVGLQVGDKINKINGNSVKTWDEVANIINTS
                     SGGELKLSITRDGSDKVVNVTPKNNNGKYEIGIQPQREKDFLGSIVNACKTTVDMTKQ
                     MLTFLGQMITGRVPGGIGNAVAGPVGVIGMVSDAARTGIINVVYLAAVISLNLGIVNL
                     LPIPALDGWRILMLLLEAVRGGKKLDPNKEGMINVVGFGALMLFMLFITYKDILRLFQ
                     "
     gene            complement(15867..17021)
                     /locus_tag="KR231_002933"
     CDS             complement(15867..17021)
                     /locus_tag="KR231_002933"
                     /EC_number="1.1.1.267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-deoxy-D-xylulose-5-phosphate reductoisomerase"
                     /protein_id="HBH0005293.1"
                     /translation="MKKISILGSTGSIGKQTLDVVRDNRDKFEIVAISANSNIELLLE
                     QIVEFKPKYVTVFEENKALKLKEMLPKNIEIEVLAGMEGLKIISSLDEVDVLLTAVVG
                     MIGLVPTLCAIKKGIDIALANKETLVTAGELVMKEAEKYNVNILPVDSEHSAIFQCLN
                     GENKKNIEKIILTASGGPFRGKKKGELANITKNEALKHPNWSMGRKISIDSSTLMNKG
                     LEVIEARWLFGVEQENIDVVVHPQSIIHSMVQYTDSSIIAQLGCPDMRLPIQYALTYP
                     DRMESSFERMNFSKFSTLTFEEPDLETFPCLKLAYECLKMGGTYSSVLNSANEVLVSE
                     FLEDKIGFYDIPYYIEKTLEVHSSISEPTLEEILETDRWSRAYVANLIKK"
     gene            complement(17185..17388)
                     /locus_tag="KR231_002934"
     CDS             complement(17185..17388)
                     /locus_tag="KR231_002934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBH0005294.1"
                     /translation="MISYAPLWKLLIDRKIKKMEFVNISGISISVLGRLGNDKSVSMD
                     TMEKICLALDCKIEDVVEIKKSI"
     gene            17725..18306
                     /locus_tag="KR231_002935"
     CDS             17725..18306
                     /locus_tag="KR231_002935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0005295.1"
                     /translation="MLYLLKINQFEKSYDIGIFKNEQSIYKFIAKIPFVKKDNSNFNY
                     TNYYMEFEDIPEYYEVNFNNYLYIITRFSFIPDGTEIFFTWEEIHCWDEKVATEKTFI
                     NGETLVDSYNFPNNEVKDYIQKRESLYIETKKYYEEKGLKIERHALGSEDGEYVELTN
                     DSILYLLDIEAVEIREQSKNIEEFLYKYKKRFK"
     gene            complement(18394..20205)
                     /locus_tag="KR231_002936"
     CDS             complement(18394..20205)
                     /locus_tag="KR231_002936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional diguanylate
                     cyclase/phosphodiesterase"
                     /protein_id="HBH0005296.1"
                     /translation="MKKKYDFLIYSAIWLVIIILFIFSLYHSIEHIKIISHTGTIRSE
                     TQKVVKQELNNERNDDLIKRLDNILIKLRTGNGENGFQRCDNKEFQQKLNQMDSMWES
                     MKKEIIKVRNGASGDKLYKLSEEYSVLSNQIVFISEKHSNAKLYSFATALFIYLIFST
                     ISLLIWEYYNKKRFKRIFYTDNLTKIKNQVAFENRAIEILHNASNKEYVLLNIDIDNF
                     KYINDTHGYEYGDKVLIIVAAALSKTFNIKETCARIGSDNFVILAKYRDSLLEDIREM
                     LTNAIISELDMNVTQTISYCIGAYLVEIDNLGYKSINSIMDKANIAHKVSKTRGISST
                     VWYNENLLKQLQMENSIYNYMYKAIENEEFHMYLQPKFQISSLNVVSAEALVRWFSPE
                     LGFLSPDEFIPLFEKSGFIIELDFYMLKKACSFVRKTFMKKNQYTYPIAVNFSRVTIY
                     QNSFYQRFLDTVKEYEIPFKYIEIEVTESAFNEISQPVISILEELKKLGFLISMDDFG
                     SGYSSLSLLCSLSINGLKLDKSLLKETFNREKVYSIIQCIIEMSHRIGMSVVCEGIET
                     KKDLEFLNTVKCDVGQGFYFSKPIEEKEFFNKYVTKK"
BASE COUNT         7084 a         3077 c         2358 g         7708 t
ORIGIN      
        1 aatagtttaa atattagcac tatttactta tatttatatg atataccata taattacatt
       61 tttcaaatta aagttttgta aacttttttt gtaatatagt gtagtataaa attgtaatat
      121 tacagatatt taatagttat cttttgatta ctttcattaa aaacagcttc atcactatga
      181 aaatctaggt ttttaaactt ttaaaaaagt taaaaaaata tttttctaat actcaatttg
      241 attacaattt ttttacaatt taaaaaatat tttttccaaa tttttatatt aatacttgac
      301 tttgtctgtt ttataaacta gaataattaa taatattaag aatattgaaa ggcattgatt
      361 aggaagagta aatctgaatc gattaccaga gaaggaaact actagctgaa atgtttccct
      421 aattagaagg attgaaaact acctaggagc ttctatccga agttatctta atgattttag
      481 taggaataga cgtttttatt acttgcgtta aagtatcaag tggatttttt aaaatcaatt
      541 tgggtggaac cgcgggaaac agattctcgt ccctttttta gggatgaggg tcttttttta
      601 ttacctaaat tcagttttta aaatattctg tatctaattt aattagctaa ttaaaaattt
      661 aaaatatatg gaggattata aaaaatgtat tattcaagta cgagaggcac cgaagaaaaa
      721 gtaactgcat cacaagcaat aataaaagga atatcaaatg atggtggtct ttatgttcca
      781 agtgaatttc ccaatgtaaa aaatgaactt ataaatttag taaatttaac gtattctcag
      841 atagcatttt ttgtacttag taaattttta tgtgatttta ctgaagatga aattaaaaat
      901 tgtatagaaa atgcatatga tgaaaagttt gattgtagta gtatagctcc attaaataaa
      961 gtaaatgata cttatttctt agaactatat cacggtccaa ctttagcatt taaagatatg
     1021 gcacttacta taatgcctca tcttcttaaa acatctataa agaaagataa tttagagaaa
     1081 gatgttgtga ttcttactgc tacatctgga gatacaggta aagctgcact tgagggattt
     1141 aaagatatag ataaaataaa gataattgta ttcttcccag aagatggtgt aagcccagta
     1201 caaaaacttc aaatgaaaac tcaaactgga aaaaatacat atgtagttgg tataaaagga
     1261 aattttgatg atgcacaatc aggtgtaaag aagatttttt ctgataaaga atttaatcaa
     1321 aaactattgg ataataatta tatattatct tctgcaaatt caattaatat aggaagactt
     1381 cttccacaag ttgcatacta tttttattca tatatgaaat tagttagcaa tagtgatata
     1441 aatttaaatg ataaaataaa ttttgttgtc ccaactggta attttggtaa tattctagct
     1501 ggatattatg ccaaacaaat gggtcttcca ataaacaaat taatatgtgc atcaaatgat
     1561 aataatgttc tttatgattt ctttaaaact ggtgtatatg ataaaaatag aacattgaaa
     1621 ttaactactt ctccttctat ggatatatta atttcaagta atttagaacg attactgttt
     1681 gaaatatcaa atagaaatac tgatattgta aataagcttt tatcagacct tagtgataaa
     1741 ggagtctaca aaataagtga tgatatggaa aaaaatttag cctcattcta tggagaatat
     1801 tcaaatgaag aagaagttaa aagcacgata aacaatgtgt ttaaaaatta taattatttg
     1861 atagatactc atactgctgt tgcatacaat tgttatgaaa aatataaaaa agaaacttct
     1921 gataacacaa aaactgttat tgtaagtact gcaagtccat tcaagttttc tgaagatgtt
     1981 ctaaagtcta tagattgtga ttttaaagac cttgatgact ttgctataat tgatagatta
     2041 tcaagtattt ctaaaataga tattccaaaa cctattaaaa atcttaaaaa tgcagaaata
     2101 ctacataaag atatttatga aaaagatgaa ttaaaactag ctataaaaaa attcttaaag
     2161 gtataggtga ttattatgtt agagattata gttcctgcaa caagtgctaa tataggtcca
     2221 ggatttgatt gtcttggaat tgcgttaaat atatacaata aattttatgt tgaagaaatt
     2281 gaaagtggtc ttgaaataga aggttgtgaa gatgcttaca aaaacgaaaa caacttagtt
     2341 tatacatcta tgaagtactt ttttgataga gttaaaccag aaaaaatacc tgctggtatc
     2401 aaaataaaaa tccaaagtga agtacctata tgtagaggtc ttggcagtag tgcctcttgt
     2461 atagtagctg gagttatagc tgcaaatgct ctatcaggtg ctaatttaga taaaaatcaa
     2521 ttactaaata tagcttcaga aatagaaggt cacccagata atgttgctcc tgctatttta
     2581 ggaaatatga ttgtatctgt tactgataat gagaatatac attatgatat tataaaaatt
     2641 cctgaagaac ttaaattttg tgcaatgata cctaatttta agttatcaac agaaaaagct
     2701 agaggtgttt taccaaagga aataccatat tctgatgggg tattcaatgt tagtagagtt
     2761 gctttactaa tatctgcctt actaaacaaa aactttgacc tacttaaagt agcttgtcaa
     2821 gacaaattgc atcaagatta tagaggaact ctaattgaga actacaatga tattgttgaa
     2881 aaatctgaac aattaaatag tattggagta tttttaagtg gagctggacc tactataatg
     2941 tctttaataa aagaaaatga tgatagtttt gtggataata tgaaaaatta cctacaaaaa
     3001 ctaaaatctg attgggaaat aaaagagtta tgttgcgatt ctaatggagc tgttttaaat
     3061 ataatataat tatcgtcttc tatacaaaat ataactactc ttttattata atttgtagta
     3121 taataattag gactaggtaa taatattaag tattataatc tagttcttta aacatgttta
     3181 cattgaggag ggattatcat aaaagagtta ataattagag atttagttgc aaaagttcct
     3241 ataattcaag gtggaatggg cgttggtata tctaggtcat cactagctgg tgcagttgct
     3301 aagcttggtg gtgttggtgt aatttctgga gttcaaattg gatatgatga ggaagatttt
     3361 gaaactaata ctataaatgc aaatttaaga gctataaaaa aacatatttc taaggccaaa
     3421 gaaatctcaa atggtggtat tattggtatt aattttatgg tagctatgaa agaatatgaa
     3481 acatacgtaa aggaagctgt taaagctggt gtagacctta taatatctgg agctggatta
     3541 cctaataagc taccatcatt agtaaaggga agtaatgtaa aaatagcacc catagtttca
     3601 actgcaaaag ctgctaatgt aattttaaaa atgtgggata gaaaagagaa aactactgct
     3661 gacttaatag ttgttgaagg tccaaaagct ggtggtcacc ttggatactc taacgaggaa
     3721 cttgataaca tagattctat agactatgat aaggaatttg ttgaaatttt aaaggttgca
     3781 aatacttatg gagaaaaatt tggtagaaac ataccagtag ttgctgctgg tggtataact
     3841 tctagtagtg atgttaaaaa atatatagat atgggtgcaa gtggtgtaca agttggtaca
     3901 agatttgttg ctacttacga atgtgatgcc catgagaact ttaaaatggc atacataaat
     3961 gctagtgaag aagatgttca tatagttaaa agtcctgtag gtcttcctgg acgtgccata
     4021 agaaacaaat ttatagaaga agttaaaata aatcgtccag aaataaagaa gtgctataat
     4081 tgtttgattc cttgtaatcc aaaagaaact ccttactgta tttctcaagc tctaatcaat
     4141 gcagttaaag gagatgttga aaattcactt ttattttgtg gaaatgatgc ctataaaatt
     4201 gataaattaa gtactgttga agatgttatc aatgaattga tttctgaatt ataatttaaa
     4261 gaaaactaaa ttaaaatttt atcaagctaa ggagtttaaa tacgttattt attaatcttt
     4321 ataaacatat ttatgtcctt agcttttttg tgtcaatttc cttttattga aattttaatt
     4381 taattagaga tagtattaac ccttataact aatcttcttt tacaagtaca ttggttattt
     4441 cagctatata taaagtatga taatcttttt gtggatacca tcttccatct ataccttcag
     4501 caataaaaca ttggggttca agtttctgac tatacatttt tttgcatata atagccattt
     4561 tagcttcctt aaaataaggt gtatcattta agtgttctat attaaatcca atctgtgata
     4621 tcttatcctc ttctctacca gatacttttc cacaatatga aagctcttta cgaaaatctt
     4681 catcaaaaaa tgtaagagaa aatttatctg tattatctat aaattcctta gtataacgct
     4741 gtggtcttat tactacaaaa gcaacatctt ttccccacat aactccaagc cctccccagc
     4801 tagcagtcat tgtattcact ttaccttcat tttctgctgt tataagtgtc caatctttac
     4861 ctatcaatcc aaatggatta tttttaatct cttctgccaa aatttcttta aaatcactca
     4921 tatctctaat aacctctcat tctcttatat ttatattcct tttattttca tgataaatta
     4981 taaatgaagt ctagttttga aaataaaata cttttttaaa tatattattg caaataagta
     5041 aatatatata tacactctta ttttttaata tatttaataa tttcactcag aatatatata
     5101 ttctttactc aaattaaata taacttatat actttatgtg taaattatgg taaaaatatt
     5161 atttaatcaa atcaaaactt gatttatata cctggaaaag gtattatatt aaagagtgct
     5221 taaaatacgc atttcataaa tagctatata taaaataata aataaggaga gtgatgggca
     5281 atggatacta gtccgttgcg gagagaattt tttacatttt catcacttaa taatatctaa
     5341 aatcaaaact aatacatata ttcagttata taaattagtt aattaataga tactattaaa
     5401 tgatgagatt tatataaaac tgaataaagg atgtgttgcc atgataagat attacaaaac
     5461 tatagattca aaattagaga aacttagttt ttttgaagat ggctgttgga taaatcttgt
     5521 tgaacctaat catagtgaaa tcaacgaaat ttctaattta ttaaatatag atgtagaaag
     5581 catagaatct gcactagatg aagaagaacg ctcaagaata gatgttgaag acaatcatac
     5641 tcttatactt atagatatac cagtagacga aagtgactct aattcttctc attatactac
     5701 aataccctta ggtattatac taactgaaga agctattgta acagtttgtg atgcacaaac
     5761 taagatttta aatgacttta tagttggtca tattaaagat ttttttacgt ttaaaaagac
     5821 tcgctttttg cttcaaattc ttcacaaaaa tgcagcttat tacttgcatt acttaagaaa
     5881 aataaataaa atgacaatca taatagagcg agaaatttac aaatcaatga aaaacaaaga
     5941 attggttcaa ttattggaat tagaaaaatc tttggtatac ttctctacct cactaaaatc
     6001 taatgaactt gttttaaaca aaatggttag aactgctggt ataaagaagt atccagatga
     6061 tgaagaccta ttagaagatg ttatagttga aaatagacag gctcttgata tggctaaaat
     6121 atatggagat atattgagta gaattatgga tgctttcagt gcaattataa gtaataatca
     6181 gaataatgtt atgcaaattt taacagtagt tacactaatt ttctcaatac ctacaataat
     6241 atcaggattc tttggtatga atgtcatcaa catgccattt tctaataacc caaacggatt
     6301 ttggataata cttcttatta cctctataat atgtatagtg attacatttt tcatgtcaag
     6361 aaataagcta ttataaaata ttaataaaaa agccattaga attaattgat ttacatttat
     6421 cctaatggct tttatatatt taaatctata taatcttata atacttttta actatcatgt
     6481 tcttcatcta taatcatttc agtttcaagc ccttctagca ttgaatctaa actttctttt
     6541 atatttagta tataaattgg tacatactct tcttcatcta ttacctcttc ttgcaactta
     6601 aatggaggaa ttaatacttc atcaaagtct atatttaaat ttggaaagcc ttctactatc
     6661 tcttcacaat tatcgtactc ttcatttgct aaagaaatgt acatatctag gctcttttta
     6721 taataaagac ctgcaagcat atactcacac ttcttacttc catatttaat accttcttta
     6781 taatatttct cagcttctgc gtcatcattt aattttaaat aaatttgacc taaattatat
     6841 attgattcaa cacaaccttg tgctctagcc ttttcatacc aaaatttaga atttacataa
     6901 tctttataga acatatcata aattaatcct accatatgtt gagcatacac attattttca
     6961 ttggcaggtg tatcaaacat cattttagac tcttccaatt taccttctct aaaataaatt
     7021 ctacctagat gtatacgagc attcatatgg tttttgctac ttgccatttc aaaatacttt
     7081 ctagcatttt ttgtatttcc taagctctca tatatacacc ccaatctata actagacctc
     7141 gtatctccat tttcagatgc tttcttatac caacttattg cttcttcaat attatttaaa
     7201 tcttcataga tatttcctaa tttgatttga caagatacat tatttggaat cctcgaataa
     7261 tacgaaatcg ctttttctat atcttgattc tgataatata aatcccctag attttcaagg
     7321 gaacttttgc atccaacagc tatagcatcc tcataatatt taatagcatt ttcataatct
     7381 ttttcttcaa aatatatacc tgccagatta ttttttgctt ctgttatatc atcttcagca
     7441 gccattttat aataagtttt tgccttctct atctcatttt ctctattata taaattagca
     7501 agtctatact tagaaagtgt atgatttttt tctattgctt tctcataata ataaattgca
     7561 tctcccagct cttcttttct atcatataca tatgcaagcc tatactcaga cttcacatca
     7621 tctctatcag cactcttttt ataatacttc tctgcatctt ctaaattatc atttatttcc
     7681 ataatcatac ccaagttaaa gcaacctttc atatgacctg acttgtacaa ctgtttatat
     7741 aaacttactg ttgatttatt atctttcttt tttccattta atattgctaa attatatttt
     7801 gcatcatcat ctaaaagcac agaacctttt ttatagtatt catatgcttc atcatctttc
     7861 tccaaaaaag tatataatac ccctaaatta aaacaagctt tacctaaatt cttgtctgct
     7921 gctgttttta accatttttc acaccttaca aaatctttca ttttaaaatg gcatacacct
     7981 aaattatttt gtgcttgtaa ataacctaaa tttgctatct tttcatacca atatatagca
     8041 tattcatagc catctaactt atagtacata ttacctaaat caaaagcagc atcttcactt
     8101 ccacttttat atgccattga ataccacttt tctgcttctt taaattgttt tttactttca
     8161 tatatatttc ctaaagtata ttgagatttt acgtaattat ccaatgcagc actcttatac
     8221 aactctattg cgctttccat cttacccatc ttttcaagga gggcaccctt agtatgtacg
     8281 actttcgggt cattagatat attttttatt ttttttatag aaaattttgt atttttcatt
     8341 attcgctacc tacccatttt ataaaatata ttctctcaaa cattattata cattataatc
     8401 tacaattaat gctataatat tgaattttta ccttttgtca ctatattgta acattaaatt
     8461 ttaaatttta taatcattag attttattat gtaattggta tataatgtat atataggggg
     8521 gacattttat gaatttcagc aatattttta tccaagttgc agttttattt ataattattt
     8581 tagttggata ttttgtcaga aaattcaact tattagatga ccactgcaca tctaagcttt
     8641 caactttgac aatgacagtt tttttaccat caatgataat tagctccatg caaattaact
     8701 ttgatagtaa aatgatacaa aaaatactat tgttattatt tacatctttg attatgtata
     8761 tagtttcaat tataattgca tttttattga aatacatttt aaaatgtaat gataaaaaag
     8821 atttgggaat ataccagtat atagttgttt tttcaaatgt tgcttttatg ggttatcctg
     8881 taattgaagc agttttaggt catgaagcaa tattctatac tgcaatattc aatttgcctt
     8941 ttaacttatt ttctttcact ttaggaattt atcttttatc taaaggcagt acaagtagag
     9001 gtttttcaat aaaatcactt ataagccctg ctacaatagc tattgttatt ggactttttt
     9061 tatttgtaac aggacttagg ttaccccaat ttataaacga gccacttgag atgttgggaa
     9121 gtataactac accaatatcc atgattatca ttggaagctt acttgctaat tcttcagctc
     9181 tcgattgttt tgtcaacaaa aaattatata tagtcacttt tataagatta ttggtacttc
     9241 ctgtgattgt gtattttatt ctaaaaggat ggataaatga taagatgatt ttagctatac
     9301 cagtagtaat ttcttcaatg cctgctgctg caaatactgc tataatggct aatcaatatg
     9361 actccaatat aacactagct tcacaatgtg tgttttttac aacactattt tcagttatat
     9421 ctataccttt tataagtatt ttactcttat cttgatttat ttttttatgt attatataat
     9481 aacatattca ataaattaca aatataaaca ttttattgta gtatattgat ggaatttttt
     9541 cctagatatt tgtcaataat atctatatgt attatagaat aggaggctta aatatggata
     9601 tggatttact ctttaaaata gtatttgcta tagttgctat aggtgtttct gtaaaaatca
     9661 ttaaaactgt tgctagttta gcttttaaaa tagcgttgat attgctaata attttatttg
     9721 tatatagaat gtttttgtaa acatttaaaa ataagttttt taacacaata gagaagtaaa
     9781 atagattatc tttaatgtaa attttttatt aaagacactc tattttactt ctctattagc
     9841 ttatttaaat taaattttta ttatatcttc ccataatata aacatcttca aattttccat
     9901 ctctgattac agcatatttt ttagttccct ctatttcaaa acctagcttt ttatataaat
     9961 ttaatccctt ttcattatcc acaattactt ctaatcctac tctagttaac ataatccaat
    10021 tatctgctat atctaaaagt tgttccataa gcttcttacc tactcctctt ccctgataat
    10081 tctctgcaac acttattcct atttctgcgc tatgtctcaa tcgtggagaa gaatttacat
    10141 gtaacccagc aaaacctatt acatcttttt ctccattatt attagtttca gctacaaaca
    10201 tataatcatt ttctcccaaa gaagctaaca tagcttcagt tttatcgact ctgtcactca
    10261 ttaatgccaa agtatttctc ataacactgt atgttcttct aatttcatta aaagcttgtg
    10321 catcttctct tcttataggt cttattgtta tatctatagg cttactcata ttggattccc
    10381 cctcaaacat aatctttatt tttaattaaa attttacatc tttattttat actgttcaaa
    10441 tctatgtatg cttctacctg aggtacatat atcatattat cttttatatg tgtacttcca
    10501 aattctttta attctgtacc ttctttatcc ttagttattt tatatctaat ggattccata
    10561 ccttcaacta cttcagcatg aaaaaacata ccttcatatt gtttaaatct aaaattaaaa
    10621 ttgtctttag taagttttat tatcatattt ttatctactc cttatataat tgatattttt
    10681 cttattatta gttgtatata tactgcttat tcatattaat atattataac ttatcattta
    10741 tttagtataa agttataaat agatatattt atacttattt tacaatcttt cttcaattga
    10801 tatataatat gtttatataa actaatgtat gtgaggtgaa atatgagcaa aaaaacaaaa
    10861 tatttttctt taattctctt tcctattgct ttgcttttaa attttatagc cagcaaagtt
    10921 ccaaatattg ttgaaaaata ttactcccaa ttcatagata aaataattgt acaaatattg
    10981 agtaaagttt ctggaatttt cccattttct ctctatgaga ttacaatgta cataatagtt
    11041 atatctatct tcttattttt atgttgtact ttatctacaa tttttaataa gaaaaaaaaa
    11101 ttaaacatat atttaaaaaa ttccatttta aatatattat ccattgtatc aatagtctac
    11161 tttctttttg tagtgctttg gggaataaac tataatagga ttccactaga aaccacactt
    11221 ataaataact ataatttaaa aaacaatacc tctatccaat caaaacaata tagtgttaaa
    11281 gagcttacta aattatataa attccttgta attaaagcaa atgaaactag aaaactcaca
    11341 ttacaagata aaaatggtat tgtaaaatct aatacagatt ataatggtgt cataaataga
    11401 gctcaactag gatacgataa tatcttggat atattacctg gtgttagtgg tagttattct
    11461 aagcctaagt atattatttc atcaaatcta atgtgctata caggaataac tggtatatac
    11521 tttcctttta caggtgaggc aaatgtaaat atagcaatac ctgacttata tattccttgt
    11581 acagttgaac atgaaatggc acatcaaagg ggatttgcta gtgaagatga ggctaatttt
    11641 atagcgtatc ttacttctat aaaacacccc aatattgatt ttaactattc tggatatatt
    11701 ttagctttaa attatactgc ttctgcttta agtaaggttg attataatgc atatgttgat
    11761 atttctgctg gcatttcaga ttctgtccgt agagatttaa aaaatgaaag tgaattttgg
    11821 caaaaatatg aaggtaaaat taatgaaatt tctaatgagt ttaacaattc ttacttaaaa
    11881 gctaatagcg ttactgaagg tactcagagt tatggtaaaa tggttgattt attgctaact
    11941 tattatgaat tatatccata taactaaaca ctacaattca aaattttatt catatacagc
    12001 tgatattaaa tcagctgttt tctatttaaa taaattattt aacttcaagc aatcttatat
    12061 aatttgatag tacttatact atctgtataa catttcaatt ctaactattt tagttaaaac
    12121 atttctatta tcttttttaa taaatgtttt aactaaaatt tttaaaacat aaaacttcca
    12181 cattatttca ctatctatat aaaaatctaa aaattcacat ataaaattac ataactaaaa
    12241 aatcataaat ttatagaaaa catatattca aaataaaaaa gcatgtatca aaacttgaca
    12301 catgcttata atcttatgta tatatatcat tttgtcacaa taaaaattta cttgtaacac
    12361 tgatattttt aaacaaaata gtccttattt aattaaatta acattaatta aattcgtact
    12421 cattttgcta tcattaaaca ttacttatag taattttcta atacactatt tgaaacttcc
    12481 ttcccttgaa aacttttcaa ccaattctca tatgctgagt ttttccatac actaccatca
    12541 ttaaatgtta cttgttttac acaagatata atgtacttta caccatgctc tccagttgat
    12601 tgtttccatt tatcaaacaa tagaaaggca tcattttgat tcttacctgg tgctattgca
    12661 ttttgctttg catattcttt ctccatttgt ttccattctt tcaaccaatt ttctacccat
    12721 gccttgcctt gttgtttttc aaacatactt attatatcct gtggtggtga ttgttgcatt
    12781 tttctataag tatgtgaata tgattttgga gacacaggag atatgcctgt aacaatacca
    12841 tagtctacac cagctgggct aaatccaaca cttcctactt cgccatctgc tgccacattt
    12901 tgagcatccc aatatagctc aagtggtttt ccatttttat catatgctaa gcatgtaatt
    12961 tcataatcca taattgcctt ttcactgcta tttgttaagc ttataacatt gctaggccaa
    13021 tgatatggag tatcatcata ctgtattttg ctattattta taaataatgg aatattctca
    13081 ttataaacaa gacctttact actttgaata tctgatacct tctttgtgac agtacttacc
    13141 gtatttgcta agtatacatt tgttttttct gaattggtcg tactaagaga aaatgttgtt
    13201 gtcgttccag taatcagcaa agcaacaact aaaataggta agctagatat ttttttatat
    13261 ctcacaattc ttcacctctt tttctattaa cttataataa aacaatttac caaaacatta
    13321 aaatctatgt taacataatt taccaactgt tctagtaact atatcctatc atagttacta
    13381 tcaagtttca atactattga tggaaatttt cactatatta aatctttttt taattttata
    13441 aatttacaat atgatttaac tcatacatat atagtcaaat tagaatataa gtttcttaca
    13501 tttaatgaag tttataaaat aaaaaatgac tagataatta aatactgtaa ataaaaactt
    13561 attacaaaag tatttaaaaa tctagtcaat taatatatat atgaattgta tactataatt
    13621 tttcaatctc ttctagcaac tcatcaacta atttgttacc atcaatcatt ctaactattt
    13681 cacccttttt aaataaaaga ccttcacctt tacccccagc aatacctata tctgcctctc
    13741 tggcttcacc aggtccattt acagcacagc ccataattgc aacagtgata tttttttcca
    13801 tactaccaat cttttcttca acctcattta caacactaat taagtctata ttacatctac
    13861 cacatgtagg gcatgatata actttaatct tatcatttaa aagtcccaaa cttcttaaaa
    13921 tctgtttacc aacaataacc tcttcaacag ggtcgcctgt taaagatatt ctaacagtat
    13981 ctccaattcc tttaagaaga agtgctccta cccctataga agactttatt gttcctttgt
    14041 gaacacttcc agattctgta attccaatat gaagaggata atcaactttt tttgatatta
    14101 attcatatgc atcaacagtt ttataaatat cggatgattt tagagatata actatattat
    14161 gaaaatctaa gtcttcaaga atcttaatat gtcccattgc actttcaact aatgcttcag
    14221 cagttgcaga gccatacttt tttaaaagtt ctttctctaa agaacctcca ttaactccaa
    14281 ttctaatttt taaatttctt tccttgcatt tctcaactac catcttaact ctctctatac
    14341 ttccaatatt accaggattt attcttattc catccacacc ttgttctata gcttcaaggg
    14401 ctagcttata atcgaaatgt atatctgcaa taattggtat atttacacta gactttatct
    14461 ttgctatatt tttagcagct ttaatatcag gaacagcaac tctaactata tcacaaccag
    14521 cttcctctaa tctctttatt tgagctattg tagcatctgc atctcttgta tcagtatttg
    14581 tcatagattg tatacttata ggattttctc ctcctatttt tacagttcct acacttactt
    14641 ctctcgtctt tcttctctcg taactcatat tccacctcta tatattattt tatattgaat
    14701 ctctttaaat attaaaatat tataacctac atgtatatta taaattaaaa agctatctag
    14761 ttaaataaga ataaatttca tatataaaaa ttaatttatt cttatttaaa actacatagc
    14821 ctattttctt aaaatctcta aaaactaaat cattgaaata atcttagtat atctttatat
    14881 gtgataaaaa gcataaataa cattaaagct ccaaaaccaa caacatttat catgccttct
    14941 ttatttgggt cgagtttttt accacctcta acagcttcta gtaacagcat aagtattctc
    15001 catccatcaa gtgctggtat tggtaataga tttactatac ctaaatttaa gcttatgaca
    15061 gctgctaaat acactacatt tatgatgcct gtacgagcag catctgatac cataccaata
    15121 acacctactg gtcctgctac agcattgcca atccctcctg gtacacgtcc tgtaatcatt
    15181 tgacctagaa atgttagcat ctgttttgtc atatctacag tagttttaca tgcatttact
    15241 attgacccca aaaagtcttt ttctctttgt ggttgaatcc ctatttcata ctttccattg
    15301 ttatttttag gtgttacatt tacaacttta tcacttccat ctctagttat actaagtttt
    15361 aattctccac cagaagaagt atttattata tttgcaactt catcccaagt cttaacagaa
    15421 ttaccattaa ttttatttat cttatctcct acttgaagcc ctacagcctg tgcaggagta
    15481 tctggcatta tctttcctaa tttagtcgtt ggagaaccta tatacaaaaa tactggaact
    15541 aaaagtattg ctgctaatat tatattgaat attggtcctg ctacaatagt actaaatctt
    15601 tgtaatatag acttgtttcc aaaagaattt ggacttattt gttcttcatc ttcaccttcc
    15661 atgctgacat atccaccaat tggaagtgct cttatagaat actctgtatc tttttttaca
    15721 ctatatatct taggccccat acctatagaa aactcattta ctttgatacc acttcttttt
    15781 gcaaatataa aatgtcctaa ctcatgtatt aatacaatta tactaaatag tattaatgcg
    15841 gctattatag tcataaattc accttcctat ttttttatca gatttgcaac ataagctcta
    15901 ctccatctat ctgtttctaa gatttcttct aatgttggtt cacttatgct actatgaact
    15961 tctaaagtct tctctatgta atatggtatg tcatagaaac caattttatc ctctaaaaat
    16021 tcacttacta aaacttcatt tgctgaattt aaaacagagg aataagttcc tcccattttt
    16081 aaacactcat atgccaattt taaacatgga aaagtttcta aatctggttc ttcaaaagtt
    16141 aaagtactaa attttgaaaa attcattctt tcaaagctac tttccattct atctggatat
    16201 gtaagagcat actgtattgg tagtctcata tctggacatc ctaattgagc aattattgag
    16261 ctatctgtat actgcaccat tgaatgaatt atgctttgtg ggtgaactac tacatctata
    16321 ttttcttgtt ctactccaaa taaccatcta gcttctatca cttcaagtcc tttattcata
    16381 agcgttgaag aatcaatact tatttttctt cccatactcc aatttggatg cttcaaagct
    16441 tcatttttag ttatatttgc aagttctccc tttttctttc ctctaaatgg accaccagat
    16501 gctgtaagta ttatcttttc tatatttttt ttattttctc catttagaca ttgaaatata
    16561 gcactatgtt cactatcaac aggaagaata tttacattgt atttttctgc ttctttcatt
    16621 acaagttcac cagcagttac caacgtttct ttattcgcta atgctatgtc tattcccttc
    16681 tttatagcac aaagagttgg gactaatcct atcataccta ctacagcagt taaaaggaca
    16741 tccacttcat caagtgatga tattattttt aatccttcca ttcctgctaa aacttctatt
    16801 tctatatttt taggcaacat ttcttttaat ttcaatgctt tattttcctc aaaaactgtt
    16861 acatatttag gtttaaactc tactatctgt tctagcaata attcaatatt actgttagct
    16921 gatattgcaa ctatctcaaa cttatctcta ttatctctaa ctacatccaa agtttgttta
    16981 cctatagagc ctgtagaacc taaaattgat atctttttca tataataatc ctttctaata
    17041 ataaatatac cctgtcaaaa cattataaca ctactaaaac aattattttt actattcata
    17101 gaaatttcat atattattcc acagattaaa attaatctat tattttttgt attttgtgga
    17161 atattataaa atattctagt attattaaat gctctttttt atttccacaa catcttctat
    17221 tttacagtct agtgctaaac atatcttctc cattgtatcc atagaaacag atttatcatt
    17281 tcctagtctg cctaaaacag aaatacttat acctgatata tttacaaatt ccattttctt
    17341 tatttttctg tcaattaaca atttccataa tggagcgtat gaaatcatgt tatcacctcg
    17401 caaaatatat tctatcacat tttatctatt ttggaaaatt ttcatctatt tagataaata
    17461 attatttatc taaatagatt tcaattatag tttattaaat ataaatatgt taaaataaaa
    17521 caaaagcata agttcaaaaa ttaaacttta tatatattta tctcattatt ttactaaaac
    17581 ataactatat aaaaaatatt tactattata tatctattta aaacacatta ttatagtatc
    17641 atataaacat atgtaaatat ataattaaaa aagctaaaga ttagtaaatt tataaaaatt
    17701 atattttgaa taaaaggaga aagaatgttg tatttattaa aaattaatca atttgaaaaa
    17761 agttatgata taggaatttt taaaaatgaa caatcaatat ataaatttat tgcaaaaata
    17821 ccctttgtaa aaaaagataa tagtaatttt aattatacaa attactatat ggaatttgaa
    17881 gatattcctg aatattatga agtaaatttc aataattatt tatatattat taccaggttt
    17941 tcattcattc cagatggaac tgagatattt tttacttggg aagaaatcca ttgttgggat
    18001 gaaaaagttg ctaccgagaa aacttttata aatggcgaaa cattagtgga ttcatataac
    18061 tttccaaata atgaagtgaa agactacata caaaagcgag aatcattata tatagaaaca
    18121 aaaaaatatt atgaagaaaa aggattaaaa attgagagac atgcactcgg ttcagaagat
    18181 ggtgaatatg ttgaacttac aaatgattct atactttatt tactagatat agaagcagtt
    18241 gaaataagag aacaatcaaa aaatatagaa gaatttctat ataagtataa aaaacgtttt
    18301 aaataattta tattttaaaa tacataacag tacattgagt catttaacga gatataaaat
    18361 gactcaatgt atagactgat aaaaataatt atattatttt ttagttacat atttgttaaa
    18421 aaattctttt tcttctatcg gtttagaaaa ataaaaccct tgtcctacat cacatttaac
    18481 tgtatttaaa aattccaagt cttttttagt ttcaatacct tcacatacaa cagacatgcc
    18541 tatacgatgt gacatttcaa taatacattg aataatacta tatactttct cccggttaaa
    18601 ggtttcttta agtaagcttt tatctaactt caatccatta atagatagag aacataaaag
    18661 acttaatgaa gagtatcctg aaccaaaatc atccattgaa attaaaaatc ctaacttttt
    18721 aagttcctct aaaattgaaa taactggttg agatatttca ttaaaagcac tttcagttac
    18781 ctctatctct atatacttaa aaggaatttc atattcttta acagtatcta aaaacctttg
    18841 ataaaaacta ttttggtaaa tagtaaccct tgaaaaatta actgcaatcg gatatgtata
    18901 ttgatttttt ttcataaacg tttttcttac aaatgaacac gcttttttta acatataaaa
    18961 gtccaattca ataataaatc cacttttttc aaacaatgga ataaattcat ctggtgataa
    19021 aaaaccaagt tctggagaaa accatcttac aagagcttct gcgcttacaa catttaaaga
    19081 agatatttga aatttaggtt gcaaatacat atgaaattct tcattttcta tcgctttata
    19141 catataatta taaatactat tttccatttg taactgtttt aacagatttt cattatacca
    19201 tactgtggag gaaattcctc ttgttttact taccttgtgt gcaatatttg ccttatccat
    19261 tatagaattg atggatttat aacctaaatt atcaatttca actaagtacg ctcctataca
    19321 ataagatata gtttgagtta cattcatatc taattcagag attatagcat tagttagcat
    19381 ttcccgaata tcctctaaaa gagaatctct atattttgca agtattacaa aattatctga
    19441 accaattctt gcacaagttt ctttgatatt aaaagtttta gaaagtgcag ctgcaactat
    19501 tattagaact ttatctccat attcatatcc atgtgtatca ttaatatatt taaaattgtc
    19561 aatatcaata tttagcagta catactcttt gttagatgca ttgtgcaaaa tttcaatcgc
    19621 tctgttttca aatgcaacct gattttttat ttttgttaaa ttatcagtat aaaatattct
    19681 tttaaacctt tttttattat aatattccca aattaaaaga cttattgttg agaatataag
    19741 ataaataaat agtgcagtag caaaagaata caattttgca ttagagtgtt tttcagatat
    19801 aaaaacaatt tgattagaca acacagaata ctcttcactc aatttatata atttatcacc
    19861 tgaagcacca tttctaactt ttataatttc tttcttcata gattcccaca tagaatccat
    19921 ttgatttagt ttttgttgaa attctttatt atcacatctt tgaaatccat tttctccatt
    19981 acctgttctt agctttatca gaatattatc cagtcgtttt atcaagtcat catttctttc
    20041 attattcaat tcttgcttaa caaccttttg agtttcactg cgaatagtac cagtgtgact
    20101 tataatttta atatgctcta tactgtgata tagagaaaat ataaaaagaa taataataac
    20161 tagccaaata gcagaataaa ttaaaaaatc atattttttc ttcattattg ttacctcatt
    20221 tgtaata
//
LOCUS       DAEPHU010000074        19037 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 01A10CD0081
            SAMN05941466-rid12468953.denovo.074, whole genome shotgun sequence.
ACCESSION   DAEPHU010000074 DAEPHU010000000
VERSION     DAEPHU010000074.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941466
            Sequence Read Archive: SRR6291087
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 19037)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19037)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068158.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 22:43:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,892
            CDSs (total)                      :: 3,805
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 87
            rRNAs                             :: 8, 1, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 55
            CDSs (without protein)            :: 55
            Pseudo Genes (ambiguous residues) :: 0 of 55
            Pseudo Genes (frameshifted)       :: 21 of 55
            Pseudo Genes (incomplete)         :: 28 of 55
            Pseudo Genes (internal stop)      :: 16 of 55
            Pseudo Genes (multiple problems)  :: 8 of 55
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19037
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941466-rid12468953.denovo.074"
                     /strain="01A10CD0081"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            159..671
                     /locus_tag="KR231_002937"
     CDS             159..671
                     /locus_tag="KR231_002937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0005297.1"
                     /translation="MKVKKFKSGIVMALTVMAIGASLTNVSAMELNKSKEFETKYNEM
                     KMDFQEEYGKEDKFNITLDDEFTKEEVNGAKGIIKTTNKMNNEVVVLNYFDEMKSGIE
                     FELKPKAEKNAILRDEFQQGYGKEDKFKVVLDDEFTKEEVNGAKGIIKTTDKETGEVI
                     VYNYFDELEK"
     gene            complement(1124..2221)
                     /locus_tag="KR231_002938"
     CDS             complement(1124..2221)
                     /locus_tag="KR231_002938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine--glyoxylate aminotransferase family
                     protein"
                     /protein_id="HBH0005298.1"
                     /translation="MKKTYLFSPGPVMVTDKVRNSLLHYDICHRGNEFMDLFKDTQQK
                     INKLYNATSNYYSLIVSGSGTSVNECVLSSIFDKEDAVLLVSNGVFGERLEEILSTYN
                     VKTYKPNFEWAEYPDLDILEKYIIENSDIKVIAMVFHETSSGMINPVPELGKLAKKYN
                     KIFFVDAISASAGEYIDVEEFNIDIITGVGGKALGAFPGSAYLCAKESILQNIKENQC
                     KNVYLNLYKHYKVAKSSSQTPNTPNVTLIFALNEALTEFLEDDSKIERYKECSAILRN
                     GMEELGLTFLLPDKYMSNTVTSVFLPKEINVNEFILGLERESGYVVYPGKGKFLDANI
                     FQVANMGEIYPEDCYKFLDILKSKLEIKKVI"
     gene            2514..4040
                     /gene="glpK"
                     /locus_tag="KR231_002939"
     CDS             2514..4040
                     /gene="glpK"
                     /locus_tag="KR231_002939"
                     /EC_number="2.7.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol kinase GlpK"
                     /protein_id="HBH0005299.1"
                     /translation="MKYVLAIDQGTTGTRAVLINEKSEFVFSDYMEHTQIYPQSGYVE
                     HDPIEIWNNTKTVSNNVLQQAFENGINESDIKGIGIDNQGETVMLWDKNTGKPLYNAI
                     VWQCRRTYDYVENLKNIPGLENKIIDKTGLIIDPYFSGTKIKWVIDNVKGVKEKIKNG
                     EVLAGTLDSWLIWKMTGGKSFLTDVSTAARTMLFNIRDMDWDRELLDIIGVPRSILAD
                     IMPTSGDFGTTDKEAFCGVSIKITASMVDQPAALFGNGCFEPGMVKNTYGTGCFLYMN
                     IGEELNIAGNGILTTVAWKIGDKVTYAYDGGVYIAGAAIQWLRDGIGVIKNYSETDDM
                     ANSISSTGGVYFVPAFAGIAAPYWDQYARGTMVGITGSTKKEHIVRATLESVALQVKD
                     VVDSMNLASGKKIKMLRVDGGITKNNFTMQFQSDILGIPIEIAENPETTVLGVGYMAG
                     LSCGVWNSIDEIRSEFTISKKYIPNMTTQKREEILLGWNQAVKRAMNWENDTKKVCAN
                     "
     gene            4081..5196
                     /locus_tag="KR231_002940"
     CDS             4081..5196
                     /locus_tag="KR231_002940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ethanolamine utilization protein EutH"
                     /protein_id="HBH0005300.1"
                     /translation="MPFDKIILYIMAVGVLLGALDRIIGNKFGLGEQFEEGFNSMGPL
                     ALGMVGIVCLAPVISDVLGPIIIPIFNLCGADPSMFATILANDMGGYPLAMELAHNKE
                     AGMLAGLVVSSMLGCTLVFSIPVGLGLIEYEDRPFFAKGLLIGLITIPFGGIIGGLIA
                     GFNLSMVIINMIPVIILAVILAVGLKFNSTLMINGSLVFGKFISILITIGLGAAAFQE
                     ITGIVLIKGMTPIREGIQVIGSIAIVLLGTFPILHLLVKVLNKPLTIVGGKLGMDATS
                     AAGLVFTLANSIPVYKMMKDMSPKGKVVNTAWLVCATAALGDHLGFTAGVVPEMITPV
                     VIGKLVGGVLAIALAILMTKDLTLEEEQSIKMKKDAV"
     gene            complement(5477..6241)
                     /locus_tag="KR231_002941"
     CDS             complement(5477..6241)
                     /locus_tag="KR231_002941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HBH0005301.1"
                     /translation="MLPQERYEKILSILKSDNIIKINDIVQMFDISIETARRDLAHME
                     SIGLLKRVYGGAIPVIASSVELNYVKRKKINSNDKKQIAIKCSEFINTNDTIFMDTGT
                     TVLEVSKNLKDKKNLTVITNSILVANELMNTNIKVYVLGGYLRETEGSFSGPLTLSAI
                     EQFNVDKAILGAGGITLENGISDYHLEEALVRKKMIERSRKSIVVVEPPKFGINSFAS
                     VAPIEHIDTIITSASIDHNIIIEFSQKGIPLVIADN"
     gene            6500..6590
                     /locus_tag="KR231_002942"
     tRNA            6500..6590
                     /locus_tag="KR231_002942"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:6534..6536,aa:Ser,seq:gct)
     gene            6678..7466
                     /locus_tag="KR231_002943"
     CDS             6678..7466
                     /locus_tag="KR231_002943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar motor protein"
                     /protein_id="HBH0005302.1"
                     /translation="MTTLIFFIVGIASLVVAFVIDGGHVGALFVFSSALVVFGGTIGA
                     VGASTPFPVFKKSIKIMLLTFKNKKPNNIENIIYFKEIATKARKEGLLSIDKEISEND
                     ELDPFIRKGLELMVDGVDAVTIRNILESQIQITSKRHKEGIAIFDSAGGYAPTLGIIG
                     TVMGLVHILGNLSSNPDALGPQISVAFLATLYGVGSANLIWLPIASKLKAINQQEVSE
                     RLLVIEAILSILEGDNSNLMTEKLKIFLNSKELIELEEIGGRAE"
     gene            7487..8227
                     /locus_tag="KR231_002944"
     CDS             7487..8227
                     /locus_tag="KR231_002944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="OmpA family protein"
                     /protein_id="HBH0005303.1"
                     /translation="MLYDEDEKEENNERWLLTYSDLITLLMIFFVIMYSMSNVDAEKY
                     KQLSQSLNSAFGGSSGVIEGGNSKIEPVVEPGSNDLDTLQNAKFKKIGEEIQKYLNEN
                     GMANSVSLRVQDRGLVISLKDTILFDTGKAIVKDNSRDKIIQIGKMLNEMNSYMRVEG
                     HTDNMSIKNSEFKSNWDLSVMRATNVVQLLIDNAGIAPDKLSAVGYGEFRPIAENSSE
                     EGRSKNRRVDIVLVDSKYDNVENVSKDK"
     gene            8403..8777
                     /locus_tag="KR231_002945"
     CDS             8403..8777
                     /locus_tag="KR231_002945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0005304.1"
                     /translation="MGNKNKNTKYKDKTRERYNKKVENLNKEKLNKINKQSKKVDKID
                     DIINKSSIVLCVLLVVFSLLYLFKLVQLNIIMILLVITVAIQQGLVSFGAFRNKNYVK
                     ALFSIFVIVCFLIAFKYVVNPV"
     gene            8869..10329
                     /locus_tag="KR231_002946"
     CDS             8869..10329
                     /locus_tag="KR231_002946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HBH0005305.1"
                     /translation="MNRCKFAKLIITSMIVLLLTGCSLKKEDNYKLDPENPTSIQIWH
                     YYNGQQKMAFDKLVKEFNDTVGAEKGIIVEAFSQGNVVDLSEKVLDSANKKVGSEDVP
                     NIFAAYSDTAYEMDKLGLLVDMDKYISKEELNEYIDEYVEEGRINSKDEFKLFPIAKS
                     TEILMLNKTDWDKFAKATNSNINDIKTIEGLVETSKKYYEWTDSLTKEPNDGKAFFGR
                     DALANYIIIGSKQLGVEIFSVKDGKVTLNIDEKVMKKLWDNFYVPYINGYFASYGKFR
                     SDDAKTGDILALVGSSSGAAYFPDRVMLNDNESYNIETSVFQAPRFKGEGKYAVQQGA
                     GMAVTKSTKEEEYASVEFLKWFTDKEPNIKFSIASGYLPVKKKTNDLDVIKEVMKKDN
                     LSLSDKVEGSIASSIEQINSCNLYTNKAFDGGTKARQILEYSMLDKAKEDSNKINELV
                     KSGTSKKDAVAQFNNDKNFKTWFESFKAELENAIKK"
     gene            10382..13411
                     /locus_tag="KR231_002947"
     CDS             10382..13411
                     /locus_tag="KR231_002947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EAL domain-containing protein"
                     /protein_id="HBH0005306.1"
                     /translation="MENNLRKNNSIMKKMIFPLIIVMLIQTSLFCATILWGGTIKKLN
                     DNSFDILNERVINRKNYIQNEMLQRWSNTSETEATINSSVKKVLNEKNALIEDVGNNE
                     EINKDIIKSISNDLIYLLRKNSVTGAFIILSDKNINDKSIDSKGEISRTGLYIRDLDP
                     KFNPNDNSDLLIERGSSDIARSFGISMDSYWEPKFSFKSENEQDGDDFFYKPFRAAID
                     NPNVSSSNLGYWGSKFLLTNAGDRLMTYTVPLIYEDGTVYGVLGIDLSVNYLRELLPY
                     SEINGNKKGNYILGVDRNNDMAFENVISNGYSLKEKFWDGLHSNLEQKESYKNIYKIK
                     NKDNECGNGNIYASVQYLDLYNSNTPFENERWALLGIIEEKSLLSFSKRVEKLVIISI
                     AISLLIGLIGIYIASRLFTKPIVLLANKVRNSNPSKPVNLDKINISEIDELSSAIELL
                     SANVADSSSKLSQIIEMVDMPIGAFELYKNAENVFCTKEFFSVFTTEIKFEEYGYMEK
                     NKFLKKLRGLDKYLQESYETENTYIYKFESKDKKLKWIRMNIFEDELKVLGVVVDVTK
                     EFIEKRKIEYERDFDILTNLLNRRAFHSQIQEKFKNKDELKIAAFIMWDLDNLKYIND
                     TYGHDAGDEYIRCAADILKKFISWNGIVSRLSGDEFYVFIYGYESKDSIRDIINSVKK
                     QMNNTLLKLHDGTEFKIRASAGISWYPDDSTNYDELMRYADFAMYQIKNTIKGEVSEF
                     DINIYNKDSFLLSNREELNKLIDGQLVEYAFQPIVDCKGKVFAYEALMRPKIKTFSSP
                     IDVIRLARSQSKLYQIERITWFKALKSFKKYKEKFGDCKLFLNSIPNNNLSKVDFEEI
                     EDLYGEYLNRVVLEITENDKINEDFIEKKKAYIDHWNIEIALDDFGTGYNGDAVLLYI
                     MPDYVKIDMSIVRGIDKDENRQKILKNLISYSNERNIKVIAEGVETKGEMETLINLGV
                     DYMQGYYISKPSFIPEDISDKIKKELKICHENRNDVV"
     gene            13488..15554
                     /locus_tag="KR231_002948"
     CDS             13488..15554
                     /locus_tag="KR231_002948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888557.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent helicase"
                     /protein_id="HBH0005307.1"
                     /translation="MVELIITTNIDIRKLNENQLEAVEHIDGPCMILAGPGSGKTRVI
                     TYRIANMVVNKNIAPTRILAISFTKASSIEMKNRALNLSDDIRLNKVTYGTFHSVFFK
                     ILRYFERYNLDSIFDEKSKRMTIKAILKSLNIENADDDENIGQVINEISYVKNELMDK
                     NEFNSEVLTKDEFLKVYNLYEEQKSKVNKIDFDDMLIRTYYLLLNNKSALEMVRNVYK
                     YILIDEFQDINKVQFEVLKLICSPLNNIFAVGDEDQSIYGFRGARPDFLLEFEQYFNN
                     TKKIILDINYRSKSEIVHTANRLIDKNKNRYEKIIKCSQGDGGSVTYISPHDSEEEAL
                     YIAREIIDEIQKDYVEYSDFAVIYRTNIQSRALVDVFMDMRIPFVVKDSVITIYDHWA
                     SQDILAYLRIGINPKSNKDWLRIINKPFRYISKDSINMVKDEKDFITALINKCNLHPK
                     QVKTINDLEIDLSYLNTLNPKNAISYIRTSLDYDRYVLDYCSNRKIKTNGLVEILNEL
                     ESSATNFNTVTEFLEHIDRVKTELTENNKNKQTEGVIFTTMHSAKGLEFRNVYIIGVN
                     EGTIPHEKSYDICKEEKKEEQLEEERRLMYVAITRAEEKLCISSTLNKYGKKVDKSLF
                     INDIKSPTKKEIDSIGVGDKVYHKKFHEGEIIKKDGIMFTIKFKDRERILDLKTCLLK
                     NIIYTI"
     misc_binding    15937..16147
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            16373..17188
                     /locus_tag="KR231_002949"
     CDS             16373..17188
                     /locus_tag="KR231_002949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HBH0005308.1"
                     /translation="MKVFKKLLSLGLVLGLTLSLVGCSGGGEKTKLEQIKDNGKLVVG
                     TSAEFPPFEFHKVVDGKDSIKGFDIMLAEEFAKELGVKVEIKDMSFDGLIGALNADQV
                     DIVLAGMSPTPEREKSVDFSELYYLSRNAVIVKDADIDKVKTEDDLKKLRVGVQAGSI
                     QEEYVVNTLKMTTTKSLKAIPDLITELKNGNIDAVVTNEAVSLINVKKYDGIKMANTE
                     VGKDVTEGMAAAIKKSDNNKDFIELLNKKIKELQDGKKIEEFLNEASTEAASN"
     gene            17216..17893
                     /locus_tag="KR231_002950"
     CDS             17216..17893
                     /locus_tag="KR231_002950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HBH0005309.1"
                     /translation="MSLDFSFLSRFGTSFLEGTGVTVSISLVALCFGFIIGIIICMAK
                     ISKSKVLRAISSIYIEVLRGTPLLVQIYIVWFGLPQLGIRFPMLFGIPSEFIASAFAL
                     SVNSGAYVAEILRSGIQSVDNGQMEASRSLGLNYWSTMRYIIIPQAIKNILPSLANEF
                     ITLVKESSIISVIGVVEIMRTADIVKNAAFRALEPLIVAAAIYFVITFTLSRLVGLLE
                     KKLSVSN"
     gene            17952..18674
                     /locus_tag="KR231_002951"
     CDS             17952..18674
                     /locus_tag="KR231_002951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004398740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HBH0005310.1"
                     /translation="MITIKNLSKSFGDLNVLKNIDLEIAKGEIMVIVGPSGSGKSTLL
                     RCMNLLEIPTGGEIIFEGKNLVDKKTNIDEVRQNIGMVFQNFNLFPHKTILDNITLAP
                     IKLKKMTKEEAEKKAEILLSRVGLLDKKDSYPSQLSGGQKQRIAIARALAMEPDMMLF
                     DEPTSALDPEMVNEVLDVIKELAKEGMTMAIVTHEMGFAKEVADRVIFIDGGSILEDN
                     TPEEVFGNPKHERTKAFLAKVL"
BASE COUNT         7537 a         2008 c         3383 g         6109 t
ORIGIN      
        1 ttaacttcaa ctattcctca aaaaagcaac ttttaaggaa tagttgaagc aaaaagtttg
       61 gttacataat agtaatttta gttacaagaa tgaaactgta aaacttagga ttttctttat
      121 ataatttcat tgagaacatt taatttagga ggtaagatat gaaagtaaaa aaatttaaaa
      181 gtggtatagt aatggcatta acagtaatgg caattggagc atcattgaca aatgtatcag
      241 ctatggaatt aaacaagagt aaagagtttg aaactaaata caatgaaatg aagatggatt
      301 ttcaagagga atatggaaaa gaagacaaat ttaatataac attggatgat gaatttacaa
      361 aagaagaagt aaatggagct aaagggatta taaagacaac taataaaatg aataatgagg
      421 ttgtagtatt aaattatttt gatgaaatga aatctggaat tgaatttgag ttgaagccaa
      481 aagcagaaaa aaatgcaatt ttgagagatg aatttcaaca aggttatgga aaggaagata
      541 aattcaaagt tgtgttagat gatgaattta caaaagaaga ggtaaatgga gctaagggca
      601 ttataaagac tacagataaa gagacaggtg aggttatcgt atataattac tttgatgagc
      661 ttgaaaaata atgcttaaag attactttga ttgaatgaaa aggtaattgt gttgagaata
      721 taaaatgact gaataaaaac agttgtatca aaacaaacaa taatagaatg taagaatgat
      781 tgtgttgaaa atattaaatg actgaataaa aaacgattgt gtcaaaaata aaaaataatt
      841 aagtgtaaga atgattgtat caagaatata aaatgactga ataaaaaacg attgcgtcaa
      901 aaataaaaaa caattaaatg taagaataat tatgtcaaaa atataaaata aattaaaaga
      961 aaaagattat attgaaggaa aaagatttga aataggggtg aactttacat attatagttc
     1021 acccttatac aaaaatataa aatataattt attataggaa aatttaaaaa aatcagtcta
     1081 tttaatttat actgatatat tgtaggattt tacaaacaaa ctgttatata acttttttta
     1141 tctccaattt tgattttaag atatctaaga atttataaca atcttctgga tatatttctc
     1201 ccatatttgc tacttggaat atattagcat ctaggaattt accttttcct ggatagacaa
     1261 catagccact ttccctttct agccctaata taaactcatt tacattgatt tctttaggta
     1321 gaaatacaga tgttactgta ttagacatat acttatctgg aagtaaaaat gttagaccca
     1381 attcttccat accattcctt aaaatagcag aacattcttt gtatctttct attttactgt
     1441 catcttccaa aaactcagtt aaagcttcat taagggcaaa tattaaagta acattaggtg
     1501 tatttggtgt ttgagaagat gatttagcaa ctttatagtg tttataaaga ttaagataca
     1561 cattcttaca ttgattttct ttaatatttt gtaaaatact ctctttagca caaaggtatg
     1621 cagaacctgg aaatgctcca agagctttgc caccaacacc tgttattata tctatattaa
     1681 actcttccac atcaatatat tcacctgctg aggcacttat tgcatctaca aaaaatattt
     1741 tgttatactt cttagcaagt tttcctagtt cagggactgg atttatcatt cctgaactag
     1801 tttcatggaa caccatagca attactttta tatcagaatt ttcaattatg tatttttcta
     1861 aaatgtctag gtccgggtat tctgcccatt caaaattagg tttatatgtt tttacattat
     1921 aagtagataa tatttcttct agcctttctc caaaaacacc attactaact agcagaactg
     1981 catcttcttt gtcaaagata gaagatagta cacattcatt tacagatgtt ccagagccag
     2041 atacaattaa tgagtagtaa ttagaagttg cattatatag tttattgatt ttttgttgtg
     2101 tatctttgaa taaatccata aactcatttc ctctatggca tatatcatag tgaagaagtg
     2161 aatttctgac tttatctgta accattactg gtccaggact gaatagatat gtttttttca
     2221 ttgtaaagcc tccttaaaaa gttaaattta aatttttgaa tgactgatta tgtgtaaata
     2281 ttaaaatatt atgtgttatt ttaactagat tatagaataa aataataaat attgcaataa
     2341 tatttcaata aaaatacttt tttaatcact ataattaaaa ataacaaaaa atattgtaat
     2401 gaatattgca taaatccaca tgatgatata aaatataaat aacttgaata gattatatat
     2461 tcaaaaaata aaaaagaatt tattaattct gaaaataaag ggggacattt aaagtgaaat
     2521 atgtattagc aattgaccaa ggaacaacag gaacaagagc agtattgata aacgaaaaat
     2581 cagagtttgt ttttagcgat tatatggaac atactcaaat atatccacaa tctggatatg
     2641 ttgaacatga ccctatagaa atttggaata atacaaaaac tgtgagtaat aatgtattac
     2701 aacaggcttt tgaaaatgga atcaatgaaa gtgatataaa aggaattggt atagataatc
     2761 aaggtgaaac agtaatgtta tgggataaaa atacaggtaa accactttac aatgctattg
     2821 tgtggcagtg caggagaact tatgattatg tggaaaattt aaagaatata ccaggtttag
     2881 aaaataagat aatagataag actgggttaa ttatagaccc atatttctca ggtacaaaaa
     2941 ttaaatgggt aatagataat gtaaaaggtg taaaagaaaa aattaaaaat ggagaagtac
     3001 ttgcaggaac attagatagt tggttaatat ggaaaatgac aggaggaaaa tcttttttaa
     3061 ctgatgtatc tacagcagca agaacaatgc tttttaatat aagagatatg gattgggata
     3121 gagagttgct tgacattata ggagtaccta gaagtatttt agcagatata atgcctacga
     3181 gtggtgattt tggaactaca gataaggagg cattttgtgg ggtttctata aaaattactg
     3241 cttcaatggt agaccaacca gcagctttat ttggcaatgg atgttttgaa ccaggaatgg
     3301 ttaaaaatac ttatggtaca ggatgtttcc tatatatgaa tataggtgag gaactaaata
     3361 tagcaggtaa tggtattttg acaactgttg cttggaaaat aggagataaa gttacatatg
     3421 cttatgatgg tggagtgtat atagcaggtg ctgcaataca atggcttaga gatggcattg
     3481 gagttataaa aaattattca gaaactgatg acatggcaaa ttccatatca agtactggag
     3541 gtgtatattt tgtaccagca tttgcaggta tagcagcacc ttattgggac caatatgcta
     3601 gaggtacaat ggttggaata acaggaagta ctaaaaaaga gcatatagta agagcgactc
     3661 ttgagtctgt tgcacttcaa gtcaaagatg ttgttgattc tatgaactta gcctcaggga
     3721 aaaaaataaa aatgttgaga gtagatggtg gaattactaa aaataacttt acaatgcaat
     3781 ttcaatccga catattaggt ataccaattg aaattgcaga aaatcctgag acgacagtac
     3841 ttggagtagg atatatggca ggtctttctt gtggtgtctg gaacagtatt gatgaaatta
     3901 gaagtgaatt tacaataagc aaaaaatata ttccaaatat gactactcaa aaaagagaag
     3961 aaatattact tggatggaac caagcagtaa aaagagctat gaattgggaa aacgatacca
     4021 aaaaggtgtg tgctaattaa gttacaatag agtattttac atgtatagga ggaattaaaa
     4081 atgccctttg ataaaattat attatacata atggctgtgg gagtgctttt aggagcgtta
     4141 gatagaataa ttggaaataa atttggactt ggcgagcagt ttgaagaagg gtttaattca
     4201 atgggtccat tggctttagg aatggttggt atagtttgtt tagctccagt aatttcagat
     4261 gtactaggtc ctataataat accaatcttc aatctctgtg gagctgaccc atctatgttt
     4321 gcaactattt tagcgaatga tatgggaggg tatccattgg ctatggaact tgcacacaat
     4381 aaagaggcag gaatgcttgc aggattggtt gtgtcatcca tgcttggatg tacattagta
     4441 ttttcaattc cagtaggact aggtcttata gaatatgaag acagaccatt ctttgcaaaa
     4501 gggttactga taggcttgat aacaatacct tttggaggta ttataggagg attaatagca
     4561 ggatttaact tatcaatggt aattataaat atgataccag tgataatatt ggcagtaata
     4621 ttggcagtag gtttaaaatt taattctacg cttatgataa atgggtcatt agtttttgga
     4681 aaatttatat ctatattgat aacgataggt ttgggagcag cagcatttca agaaataaca
     4741 ggtatagtac ttataaaagg catgacacct ataagagaag gtattcaagt aattggaagt
     4801 attgcaatcg tgttattagg tacttttcca atattacatt tattagttaa agttcttaat
     4861 aaaccactta caatagtggg tggaaaatta ggtatggatg ccactagtgc agcaggatta
     4921 gtttttactt tagccaatag tattccagta tataaaatga tgaaagatat gagtccaaag
     4981 gggaaagtag taaatactgc ttggctggtt tgtgctacag cagctttggg ggaccattta
     5041 ggatttacag caggagtagt tccagagatg attacacctg ttgtaattgg aaaattggtt
     5101 ggaggagtat tggcaattgc acttgctata cttatgacaa aagatttaac cttggaagaa
     5161 gaacaaagta ttaaaatgaa gaaagatgca gtgtagaata aacaatactt aagtcaaatt
     5221 taaattattt taaagtagga gtttaaataa ctaaaaataa attaaaaaga cagacaatta
     5281 aaaaataatc gaataactaa aacttataaa ttaaataaaa tggcaatcaa ataactaaaa
     5341 atgataagct aactgaaagt agttacataa ttaaaatata aagtatagtt tagacataaa
     5401 tggagctaaa taaataatta tttggctcct taattttaat ttattacatc aaggaactaa
     5461 aaatcaatca tataagctaa ttatcagcta tgactaaagg tattcctttt tgagaaaact
     5521 ctattattat attatggtct atactagcag aggtaataat agtatctata tgttctatag
     5581 gagctactga tgcaaatgaa tttataccaa acttaggagg ttcgacaact actatagatt
     5641 ttctagacct ttcaatcatt ttttttctaa caagtgcttc ttctaagtga tagtcagaga
     5701 ttccattttc aagagtgata cctccagcgc ctaaaatagc tttatcaaca ttaaattgtt
     5761 caatagctga cagtgtaagc ggaccagaaa aagaaccttc agtttctcta agatagcccc
     5821 caagcacata tacttttata ttagtattca taagctcgtt tgcaactaaa attgagttgg
     5881 ttattacagt tagattcttt ttatctttca aattttttga aacttcaagt acagtagttc
     5941 cagtatccat aaaaatagta tcatttgtat ttataaactc actacattta atagcaatct
     6001 gttttttatc gtttgagttt attttttttc ttttaacata gttaagttct acgctacttg
     6061 ctataactgg tatagcacca ccataaactc tttttaaaag accgatactc tccatatggg
     6121 ctaaatctct tcgtgcagtt tctattgata tatcaaacat ttgaactatg tcatttattt
     6181 taattatatt atctgatttg agaatactta aaatcttctc atatctttcc tgtggtaaca
     6241 taaaatatcc tccttggact agtattattt tagttttggc ataacttaca attaagtcag
     6301 agtttaggta tatttgttaa tgtatgtata tttatcaaat aatattataa gtgttatgca
     6361 agataatttt accatattta aaacttacat ttaagcaaaa aagtaaaaat agatgtttaa
     6421 taattcaaaa taactcaaat tttataaaac aattgactaa aatatgattt tattatataa
     6481 tttactagta tagagatatg gagaagtact caagtggctc aagaggatcc cctgctaagg
     6541 gattaggctg ggtaaccggt gcgagggttc gaatccctcc ttctccgcca attattaaag
     6601 gctattttta ttaaagatag tctttttata atgtcataaa tgattagata tgtataacta
     6661 aagaaaggag ggaatagatg acaactttaa tttttttcat agtggggata gcatctttgg
     6721 tagttgcttt tgttattgat gggggacatg ttggagcatt atttgtattt tcatcagcac
     6781 ttgttgtgtt tggtggaact ataggagctg ttggagcttc gactccattc cctgtgttta
     6841 aaaagtctat aaagataatg ttattaactt ttaaaaataa aaagcctaat aacatagaaa
     6901 atataatcta tttcaaagaa attgcaacaa aggctaggaa agaggggctt cttagtattg
     6961 acaaagaaat aagtgagaat gatgaattag acccttttat tagaaaaggg cttgaactta
     7021 tggtagatgg agtggatgca gttactataa gaaatatatt ggaatcacag atacagataa
     7081 catcaaaacg acataaagaa ggaatagcaa tttttgattc agcaggtgga tatgcaccta
     7141 cactggggat aataggtaca gttatgggat tagtacatat tttaggtaat ctttcaagta
     7201 atccagatgc attaggacct caaatttctg ttgcattttt ggctactttg tatggtgttg
     7261 gttctgccaa tttaatatgg ttaccaatag catcaaaact taaggctata aatcaacaag
     7321 aagtaagtga aagacttttg gtgatagaag caatattatc catacttgag ggtgataatt
     7381 ctaatttaat gacagaaaaa ttaaaaatat ttttaaattc aaaagaacta attgaacttg
     7441 aagaaattgg tggtagagct gaataatata aaaggatgga atgtttatgt tgtatgatga
     7501 agatgaaaaa gaagaaaaca atgagcgatg gcttttaact tattcagacc tcataacatt
     7561 acttatgatt ttctttgtaa taatgtattc tatgagtaat gttgatgcgg agaaatataa
     7621 acaattatct caatctctaa attctgcttt tggtggttct tctggagtta ttgaaggtgg
     7681 taatagcaag atagaaccag tagttgaacc aggaagtaat gatttagata ctttacaaaa
     7741 tgctaagttt aaaaaaattg gtgaagaaat tcagaagtat ttaaacgaaa atggtatggc
     7801 taattcagta tcattaagag ttcaagatag aggattagta ataagcctta aagatacaat
     7861 actatttgat acagggaaag ctattgtgaa ggataattct agagataaga ttattcaaat
     7921 aggtaagatg ttaaatgaaa tgaatagtta catgagagta gaaggccata cagacaatat
     7981 gtctataaaa aattcagagt ttaagtcaaa ttgggattta tcagttatga gagcaaccaa
     8041 tgttgttcaa cttcttattg acaatgcagg tatagcacca gataaattat ctgctgtagg
     8101 atatggtgag tttagaccaa tagcagaaaa ttcatctgaa gaaggtaggt caaaaaatag
     8161 aagagttgat atagttttag ttgatagtaa atatgataat gtagaaaatg tttcaaagga
     8221 taaatagtta aattagctgt ctcaatacag aattaattct aaaggagatg gcttttttat
     8281 gcgaaaatca aaaatagata catagtaagt tacctttttg taggaatata tggtatctta
     8341 aatatataat atttaaataa tgtataagct caattaaaaa atttatagag gatggaaaat
     8401 aaatgggaaa taaaaataaa aatactaaat ataaagataa aacaagagaa aggtataata
     8461 aaaaagttga gaatttaaat aaagaaaaat taaataaaat taataagcaa tctaagaaag
     8521 tagataagat tgatgatatt attaataaat ctagtattgt attatgtgta cttctagtag
     8581 tgttttcatt gctttactta tttaaactgg ttcaacttaa tataataatg atacttttag
     8641 taattacagt agctattcaa caaggattgg tgtcatttgg tgcatttaga aataaaaatt
     8701 atgtaaaagc tttattttct atatttgtaa tagtatgttt cttaattgct tttaaatatg
     8761 ttgtaaatcc tgtttaaata tatcaataaa cgttctataa ttaatataaa tagtgaagtt
     8821 acagttttaa tgctattata aattttataa tttgaaggag tagattttat gaataggtgt
     8881 aagtttgcaa aattaattat cacatcaatg attgttttat tacttacagg atgtagttta
     8941 aagaaggaag ataattataa gttagaccca gaaaatccga catcaataca aatttggcat
     9001 tattataatg gacagcagaa aatggctttt gataagcttg ttaaggaatt taatgacact
     9061 gtaggtgctg aaaaaggaat tattgttgaa gcattcagtc aaggtaatgt agttgattta
     9121 tcagagaaag ttttagattc tgcaaataaa aaagttggtt ctgaagatgt accaaatata
     9181 tttgcagcat actcagatac tgcatatgaa atggataaat tagggttact agtagatatg
     9241 gataagtaca taagtaaaga agaattaaat gaatacatag acgaatatgt agaagaaggc
     9301 agaataaatt ctaaggatga gtttaaactt ttcccaattg caaaatcaac tgaaattttg
     9361 atgttaaata aaactgattg ggataaattt gcaaaagcta caaattcaaa tataaatgat
     9421 ataaaaacaa ttgaaggatt agtagagaca tcaaaaaaat attatgaatg gacagatagt
     9481 ttaacgaaag agcctaatga tggtaaagca ttttttggaa gagatgcttt agcaaattat
     9541 attattatag gaagtaaaca actaggagta gaaatttttt ctgttaaaga tggtaaagtt
     9601 acactaaata ttgatgaaaa agttatgaaa aaactatggg ataatttcta tgtaccatat
     9661 ataaatggat attttgcttc ttatggtaag tttcgttctg atgatgcaaa aacaggtgat
     9721 atattagctc ttgtaggttc tagttcagga gcagcatact ttccagatag agtaatgcta
     9781 aatgataatg agagttataa tattgaaaca tctgtttttc aagcaccacg ttttaaagga
     9841 gaaggaaaat atgctgtaca acaaggtgca ggaatggctg taacaaaatc tactaaagaa
     9901 gaagaatatg catcagtaga atttttaaaa tggtttacag ataaagaacc taatataaaa
     9961 ttctctattg cttctggata cttaccagta aagaaaaaaa cgaatgattt ggatgttata
    10021 aaagaagtta tgaagaaaga taatttgagt ttatctgata aagttgaagg ttcaatagcc
    10081 tcatctattg aacagattaa cagttgtaat ttatatacta ataaagcatt tgatggtgga
    10141 actaaagcta gacaaatact tgaatattca atgcttgata aagctaaaga agattcaaat
    10201 aaaataaatg aattagtaaa aagtggaact tctaagaagg atgcagtagc acaatttaat
    10261 aatgataaaa attttaaaac ttggtttgaa agttttaagg ctgagcttga aaatgctata
    10321 aaaaaataga tgaattggca gttagtgtgt tgacgagcac aaaggtatag gtggaatggg
    10381 tatggaaaac aatctaagaa aaaacaattc aataatgaaa aagatgatat ttcccctaat
    10441 tattgttatg ctaattcaaa caagtttatt ttgtgccaca attttatggg gaggaactat
    10501 taagaaatta aatgataatt cgtttgacat cttaaatgaa agagtaatta atcgtaaaaa
    10561 ttatatacaa aatgaaatgt tacaaagatg gtcaaataca agtgaaacgg aagctacaat
    10621 taattcctct gtaaaaaaag tattaaatga aaaaaatgcc ttaattgagg atgtaggcaa
    10681 caatgaagaa attaacaaag atattataaa aagcatatca aatgatttaa tatatctttt
    10741 gagaaaaaat tctgttacag gagcttttat aatcctaagt gacaaaaata ttaacgataa
    10801 gtcaatagat agtaaaggtg aaataagtag gacaggattg tatataaggg atttagaccc
    10861 taagtttaat ccaaatgata attctgattt gttaattgag agaggttcat cagatatagc
    10921 aagaagtttt ggaatatcta tggacagtta ttgggaacct aagttttcat ttaaaagtga
    10981 aaatgagcaa gatggagatg atttttttta taaaccattt agagctgcaa ttgataatcc
    11041 aaatgtatca agttctaatt taggatactg gggaagtaag tttttattga caaatgcagg
    11101 tgataggctt atgacatata cagttcccct tatttatgaa gatggaactg tatatggagt
    11161 acttggaata gatttaagtg taaattattt aagagaatta cttccatact cagagataaa
    11221 tggaaataaa aagggtaatt atattttagg tgtagataga aataatgata tggcctttga
    11281 aaatgtaatt tcaaatggat actcattaaa agaaaaattt tgggatggtt tacattctaa
    11341 tttagagcag aaggaatcgt ataaaaatat atataagatt aaaaataaag ataatgaatg
    11401 tggtaatggc aacatttatg ctagtgtaca atacttggat ttatataact ccaatactcc
    11461 atttgaaaat gaacgttggg ctcttttggg tattattgaa gaaaaaagtc ttttgtcatt
    11521 ttcaaaaagg gtagagaaat tagttataat atctatagca atttctttat taataggtct
    11581 aataggtatt tacattgcat caagattatt tacaaaacca attgttcttt tagccaacaa
    11641 agttagaaac agtaatccat caaaaccagt aaatcttgat aagataaata tatctgaaat
    11701 agatgaatta tcttcagcta tagagttgct cagtgcaaat gttgcagatt cttcgtcaaa
    11761 attatcacag attattgaaa tggtagatat gccaattggg gcttttgagt tatacaaaaa
    11821 cgcagagaat gttttttgta caaaagaatt ttttagcgtg tttactactg aaatcaaatt
    11881 tgaagaatat ggatatatgg aaaaaaataa gttcctgaaa aaattaaggg gactagataa
    11941 atatttgcaa gaaagttatg aaacagaaaa tacatatata tataagtttg aatctaaaga
    12001 taaaaaactt aagtggataa gaatgaatat ctttgaagat gagctaaagg ttcttggtgt
    12061 tgttgttgat gtcacaaaag aatttattga gaaaaggaag atagaatatg aaagagattt
    12121 tgatatttta acgaatcttt taaataggag agcttttcat tcacagatac aagaaaaatt
    12181 taagaataaa gatgaactta agatagcagc atttattatg tgggatttag ataatctaaa
    12241 atatattaat gatacatatg gacatgatgc tggtgatgaa tatattaggt gtgctgcaga
    12301 catacttaag aagtttatat catggaatgg tatagtatct agactttcag gtgatgagtt
    12361 ttatgtattt atatatggat atgaaagcaa agatagtata agagatatta ttaattctgt
    12421 taagaaacag atgaataata ccttattaaa acttcatgat ggaacagaat ttaaaataag
    12481 ggcatcagca ggaatttcct ggtaccctga tgactcaacc aactatgatg aattaatgag
    12541 atacgcagat tttgctatgt atcaaattaa aaatacaatc aagggtgaag ttagtgaatt
    12601 tgatattaat atatataata aggattcatt cttattgagt aatagagaag aattaaacaa
    12661 gttaattgat ggtcaattag ttgagtatgc atttcagcct attgtagatt gtaaaggtaa
    12721 agtatttgca tatgaagcac ttatgagacc taaaataaaa acttttagtt caccaataga
    12781 tgtcattaga ttagctcgtt cacagtctaa attatatcaa attgagcgta ttacatggtt
    12841 taaagcactt aaatcattta aaaaatacaa agaaaaattt ggcgattgca aattgttctt
    12901 aaattctatt cctaataata atttgtcaaa agtagatttt gaggaaattg aagatttata
    12961 tggtgaatat ttaaatagag tagtactaga aataacagag aatgataaga ttaatgaaga
    13021 ttttattgaa aaaaagaaag catatataga ccattggaat atagaaattg ctttagatga
    13081 ttttgggaca ggttacaacg gagatgctgt actattatat ataatgccag actatgtaaa
    13141 gattgatatg tctattgtaa gaggtattga taaagatgaa aacagacaga aaatattaaa
    13201 aaatcttatc tcatattcta acgaaagaaa tattaaagtg atagcagaag gtgtagaaac
    13261 aaaaggtgaa atggaaacac taattaatct tggagtagat tatatgcaag gctactatat
    13321 tagtaaacca tcatttatac ctgaagatat aagcgacaaa attaaaaaag aactcaagat
    13381 atgtcatgaa aataggaatg atgtggttta atagaggaaa aattaaattt atttttatga
    13441 acttttagtt tataattaaa aagaaaataa tataattata aatcaaggtg gtggagctaa
    13501 taatcacaac aaatatagat ataagaaagt taaatgaaaa tcaattagaa gcagttgagc
    13561 atatagatgg gccttgcatg atacttgcag ggcctggttc aggtaagacc agagtaatta
    13621 catatagaat agccaatatg gttgtaaaca aaaacatagc accaacaaga atcttggcaa
    13681 taagttttac caaggcatct tcaatagaaa tgaaaaatag agctttgaat ttaagtgatg
    13741 acataagact taataaggta acctatggta cttttcactc tgtatttttt aaaattctaa
    13801 gatactttga aagatacaac ttagacagta tatttgatga aaagtcaaag cgaatgacaa
    13861 tcaaggcaat cctaaaaagt ttaaatatag agaatgctga tgatgatgag aatataggac
    13921 aagttataaa tgaaatttcc tatgtaaaaa atgaacttat ggataaaaat gaatttaatt
    13981 cagaagtatt aacaaaagat gagtttttaa aagtatacaa cttatacgaa gaacaaaaat
    14041 ctaaagttaa taaaatagat tttgatgata tgcttataag aacttattat ttacttttga
    14101 acaataagtc tgcactagaa atggttagaa atgtgtataa atatatattg atagatgaat
    14161 ttcaagatat aaataaagta cagtttgaag ttttaaagtt aatttgtagc ccattaaaca
    14221 atatatttgc agttggagat gaagaccaaa gtatatatgg atttagaggt gctagaccag
    14281 attttttgct tgaatttgaa caatacttta ataatactaa aaaaataata ttagatataa
    14341 attacaggtc taaaagtgag atagtgcata ctgcaaatag acttatcgac aaaaataaaa
    14401 atagatatga aaaaatcatt aagtgtagtc agggggatgg aggaagtgtt acctatattt
    14461 ctccacatga ttcagaggaa gaagccttat atattgccag ggaaataatt gacgaaatac
    14521 aaaaagatta tgtagagtat tcagattttg cagtaattta tagaactaat atacagtcaa
    14581 gagcattagt agatgtattt atggatatga ggattccatt tgtagtaaaa gactcagtaa
    14641 ttacaatata tgaccattgg gcaagtcaag atatactagc ctatttaaga ataggtatta
    14701 atccaaaatc aaataaagat tggttgagaa ttataaacaa gccttttaga tatatatcca
    14761 aagacagtat aaatatggtt aaggatgaaa aagactttat aacagcatta ataaataagt
    14821 gtaatcttca tcctaaacaa gttaaaacaa taaatgattt ggaaatagat ttaagttatt
    14881 taaatacttt aaatcctaaa aatgcaatat cttatattag aactagtctt gattatgata
    14941 gatatgtttt agattattgt agcaacagaa agataaagac taatggactt gtagagatat
    15001 taaatgaact tgagagttca gcaactaatt ttaatactgt tacagagttt ttagagcata
    15061 ttgatagagt aaagactgag ttaacggaaa ataacaagaa taagcagact gagggtgtca
    15121 tatttacaac tatgcatagt gcaaaaggat tagaatttag aaatgtttat attataggtg
    15181 taaatgaagg aacaatacct catgaaaaat catatgatat ttgtaaggaa gagaaaaaag
    15241 aagaacaatt agaagaagaa agaagactta tgtatgttgc tattacaaga gctgaagaaa
    15301 agttatgtat aagctctact ttaaataagt atggtaagaa agttgataaa tcattattta
    15361 ttaatgatat aaaatctcca acgaaaaaag aaattgacag tattggtgta ggggataagg
    15421 tataccataa aaaatttcat gaaggagaaa taattaaaaa agatggaatt atgtttacaa
    15481 taaagtttaa agatagagag cgaatcttgg atttgaaaac ttgtttattg aagaatataa
    15541 tttatactat ttaatttaga atctaaattt agatagaaat ataatgtatt atttattatg
    15601 tgcaagacaa atagatatgt gtaaaatgta ttatttaact tattagaaaa agaaataagg
    15661 gtttaatata ttatttatag ttgtttagaa aaagcaacaa tgtggaaaat attatttagt
    15721 attattaaag aaaagcaaca atgtgaaaga tattatttag tattatttaa gaaatagcta
    15781 aaaatatgaa atatactatt tataattaca caaataatat caataaatat aaacagtagt
    15841 atttagataa tttacaagta aaaattatta aaaaaataaa aaacttattg acaaaaatat
    15901 tataaggaag tacaattgta ttaacaattt aaggaaacaa atccaatgat agagaaagta
    15961 gcatatatgg atttacagcg agttaggggt tggtgtaagc ctaacaatga agtctatgtg
    16021 aagagagctc tggaggagat tatcagaaac tttagtatga taattggttt acccgcctta
    16081 agggattgag aggataagta cttacttatc aaaaagagtg gtaacgcgga tataattcgt
    16141 ctcttagctg taaagctaag ggactttttt gattttaaaa taaaaatatc catacagctt
    16201 aaaagctaac agtcacaaat tttgaaagta atataagtat ttatcaataa gagtggtaac
    16261 gcggtaaagt cgtctcttag tcattaaaga ctgagagact ttttttgtaa ctcgaaacat
    16321 ttaagtatta aaatctgagg gaaattataa ttaaaagaga ggggtagtta aaatgaaagt
    16381 atttaaaaaa ttattaagtt taggattagt attaggattg acattatcgc tagtaggatg
    16441 tagtggtgga ggagaaaaaa caaagttaga acaaataaaa gacaatggaa aattagttgt
    16501 tggtactagt gcagaatttc ctccatttga atttcataag gtagtagatg gaaaagattc
    16561 aataaaagga ttcgatataa tgttggctga agaatttgca aaagagcttg gtgtaaaggt
    16621 tgaaattaag gatatgtcat ttgatggatt aataggtgct ttaaatgcag accaagttga
    16681 tattgttctt gcaggtatgt ctccaacacc agagagagaa aagagtgttg atttttcaga
    16741 attatattat ttaagtagaa atgcagttat agttaaagat gcagatatag acaaagtaaa
    16801 aactgaagat gatttaaaga aacttagagt tggagttcaa gcaggaagta tccaagaaga
    16861 atatgtagtt aacactttaa aaatgacaac tacaaaatct ttgaaagcaa tacctgattt
    16921 aattacagaa ttaaaaaatg gaaacataga tgcagttgtt actaatgaag cagtttcttt
    16981 aataaatgtt aaaaaatatg atggaataaa aatggcaaat actgaagttg ggaaagatgt
    17041 aacagaaggt atggcagcag caatcaaaaa atctgacaat aacaaagatt ttatagaatt
    17101 attaaacaaa aagataaaag aattacaaga tggcaagaag atagaagaat ttttaaatga
    17161 agcatctact gaagctgctt caaattagta agaaagttat gtgggagatg aaattatgag
    17221 tttagatttt agttttttaa gtagatttgg gacttctttt ttggaaggaa caggtgtgac
    17281 agtatcaatt tctcttgtgg cattatgctt tggatttata ataggtataa ttatctgtat
    17341 ggcaaaaata tcaaagagca aagtattaag agcaatatca tcaatctata ttgaggtttt
    17401 aagagggaca ccattattag tacagatata tatagtatgg tttggtttac ctcaattagg
    17461 aataagattc cctatgttgt ttggtatacc aagtgaattt atagctagtg catttgcatt
    17521 atcagtaaac tctggtgcat acgtggcaga gatacttaga tcaggtatac aatcagttga
    17581 taatggacaa atggaagcaa gtagatcatt aggattaaat tattggtcaa ctatgagata
    17641 tataataata cctcaagcta taaaaaatat attaccttca ttagcaaatg agtttattac
    17701 acttgtaaaa gaatcttcaa taatatctgt aataggagtt gttgagataa tgcgtactgc
    17761 tgatatagta aaaaatgcag catttagagc attagagcca ttaatagtag cagcagcaat
    17821 ttactttgtt ataacattta ctctatcaag attagttgga ttattagaaa agaaactatc
    17881 tgtgtctaac tagatgagag catgtttagc atttagggaa aacatagaat agtaaaaagg
    17941 aaagtgataa tatgattaca ataaaaaatt taagtaaatc ttttggagat ttaaatgtat
    18001 taaaaaatat agacttagaa atcgctaaag gcgaaataat ggttatagta ggtccaagtg
    18061 gttctggtaa aagtacactt cttagatgta tgaatttact agaaatacct acaggtggag
    18121 aaataatatt tgaaggaaaa aatttggtcg ataaaaaaac taatattgat gaggttagac
    18181 aaaatatagg tatggtgttt cagaacttta atttattccc acataagact attttagata
    18241 atataacatt agcaccaatt aaattaaaaa agatgactaa ggaagaagca gaaaaaaaag
    18301 cagaaatttt gttgagtaga gttggtcttt tagataaaaa agattcatat ccatcacaat
    18361 tatctggagg acaaaagcaa agaatagcaa tagctagagc acttgctatg gaaccagata
    18421 tgatgttgtt tgatgagcca acatctgctc ttgacccaga aatggtaaac gaagttttgg
    18481 atgttataaa agaacttgct aaagaaggta tgacaatggc aattgtaact catgagatgg
    18541 gatttgctaa ggaagttgca gatagagtta tttttataga tggaggaagt atacttgaag
    18601 ataatactcc agaagaagtt ttcggaaatc caaaacatga aagaacaaaa gcgtttttag
    18661 caaaagtgct ataatatata aaaaggatgt tattgatatt agaaattcaa tacatccttt
    18721 tttagtgatg gttaatatta attttaaaat taaagttata ttaatattaa ctttattttt
    18781 acgatttttt gcagaaaaaa aaagagctcg gggtaagctc tttttttcca ccgaattaat
    18841 ttccgttact aatccgattt ttaataaata taaaatatat ccttatgaaa gggtattggg
    18901 aatagatata ttaactaact agggttacca gggggataac cttaatttat tataacaaaa
    18961 tgcgacacaa aaatcaatat tttttttgaa ataaattata aaagttattt ttataacaag
    19021 taagcttata aatttaa
//
LOCUS       DAEPHU010000075        18579 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 01A10CD0081
            SAMN05941466-rid12468953.denovo.075, whole genome shotgun sequence.
ACCESSION   DAEPHU010000075 DAEPHU010000000
VERSION     DAEPHU010000075.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941466
            Sequence Read Archive: SRR6291087
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 18579)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18579)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068158.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 22:43:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,892
            CDSs (total)                      :: 3,805
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 87
            rRNAs                             :: 8, 1, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 55
            CDSs (without protein)            :: 55
            Pseudo Genes (ambiguous residues) :: 0 of 55
            Pseudo Genes (frameshifted)       :: 21 of 55
            Pseudo Genes (incomplete)         :: 28 of 55
            Pseudo Genes (internal stop)      :: 16 of 55
            Pseudo Genes (multiple problems)  :: 8 of 55
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18579
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941466-rid12468953.denovo.075"
                     /strain="01A10CD0081"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            complement(<1..349)
                     /locus_tag="KR231_002952"
     CDS             complement(<1..349)
                     /locus_tag="KR231_002952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0005311.1"
                     /translation="MNKLDALLDLANNEEIEIYYTDKIADDIKGLYINRQGLKIISLL
                     NSLKQNNAKLIEILAEELGHHFTSVGNYVSSKNSYKNKILIDKTENKALKWACEFLIT
                     EEEIIHVINSHATS"
     gene            complement(612..2201)
                     /locus_tag="KR231_002953"
     CDS             complement(612..2201)
                     /locus_tag="KR231_002953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIR2 family protein"
                     /protein_id="HBH0005312.1"
                     /translation="MKSIISDVINRFNATPFLFVGSGLTRRYYNLPNWEDLLKVFAEK
                     ISNDDFIYTSYKNKAKSENPKMGINPRIAELIENDFNKKWFSDSSIRSLDSKYLDIVK
                     SGVSPFKAEIAMYIKNNSKIVDKYQDEVEKLSNISKKSLSGFITTNYDCFLETIVDNY
                     TTYIGQENLVFSSIQGIAEIYKIHGCVSSPNSIVINEADYIDFDSKSAYLAAKLMTIF
                     VEFPIIFIGYSVTDVNIKKILNAIVNCLSNENAKKLEERFIFIEYEKNFNDIEISSHT
                     IVFDNKMITMTKIKLEDFNLLYEALSEKKSKLPVRILRMFKQEFYDFTITNKPTAKIR
                     VGSVDDTRIKDEDLVLAVGKASDFGLKGLKGLSFDEWYRDIVMNDLEFSSDELLEYAY
                     PSLIKQYNKLPLNKHLFNSTLEFPDYRTIALESDFENIISNSIKKNRNNTYIKNRSVY
                     GIWNDEHQSFEKATRLIAFLEEKEIDTEQLENLLKKIFEENPNILESAKTSEKTNLRR
                     LIRIYDYMKYSNMQKSLGYSE"
     gene            complement(2225..2788)
                     /locus_tag="KR231_002954"
     CDS             complement(2225..2788)
                     /locus_tag="KR231_002954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
                     /protein_id="HBH0005313.1"
                     /translation="MSILSDRLKFLRKEKGVMQKEIANYLNITTSAYGFYEQGKRTPT
                     PEMLSSLAEYFGTTVDYLIGRYDNKASNISSKTSCNNTLFQKRLKELRAEKNMTQEDV
                     ANKLNLTKSAYGYYEQGKTVPDAYMLSSLAEIFNVTTDYLLGRSIVKNDIDTVAAHRV
                     NPHKDLPEEAQEQLNDYIEFLINKYKK"
     gene            2941..3162
                     /locus_tag="KR231_002955"
     CDS             2941..3162
                     /locus_tag="KR231_002955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBH0005314.1"
                     /translation="MNNLKELRTERNLKQKDVALKVGITTSYYGMIESGTRVPSLAIA
                     IKLSKCFGVSIEKIFLNTNTTRCCLKERS"
     gene            3165..3980
                     /locus_tag="KR231_002956"
     CDS             3165..3980
                     /locus_tag="KR231_002956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage regulatory protein/antirepressor Ant"
                     /protein_id="HBH0005315.1"
                     /translation="MKDLKIVKVNNKLTTDSRDIALMVEKEHKILLRDIRNYINQMEE
                     ANKNMSTDLYPSDYFIENTYLDDYKREKPCYAITKIGCDFIANKMTGIKGTAFTGIYT
                     KKFEEMEQVLKNEQPKLPTTYKEALQHLIEQVEVNEKLQLEGKMKDQVIKELKPKADY
                     TDMILKNKGLVTITQIAKDYGMSGKEMNKILHERGIQYKQSGQWLLYKQHQGKGYTHS
                     ETIDITRSDGMTDVKMTTKWTQKGRLFLYDLLKVNNILPDIEKEYSYQTSMLC"
     gene            complement(4159..4338)
                     /locus_tag="KR231_002957"
     CDS             complement(4159..4338)
                     /locus_tag="KR231_002957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Arc family DNA-binding protein"
                     /protein_id="HBH0005316.1"
                     /translation="MSTSLPKYTLRINRVLLEKIKYIAESEGRSANKEIEQIIKKHIE
                     DYEQRKGEIKINIEE"
     gene            4474..4653
                     /locus_tag="KR231_002958"
     CDS             4474..4653
                     /locus_tag="KR231_002958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0005317.1"
                     /translation="MNSNKKRITVRMPEKLNEEITKKSKYLGLTKNSFILDILWKEFE
                     LLEYRSYKKEVDKHE"
     gene            4646..5437
                     /locus_tag="KR231_002959"
     CDS             4646..5437
                     /locus_tag="KR231_002959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ORF6N domain-containing protein"
                     /protein_id="HBH0005318.1"
                     /translation="MNNLQVIERNNERVLTTQQLADVYETDSRNISNNFNNNKDKFIE
                     GKHYFLLQGDDLKNFKGIHTEYENLKFASKMYLWTERGANRHCKILDTDKAWEQFDNL
                     EETYFKVKQHKPTCIEDVLIESLKEMKDLRLQVNQANSIALEAKTEVETIKDVVSLDS
                     NSWRTNTHQLIARIAKKQGGFEHINMLRTESYELLNKRFGVDLHRRLINKRRKMAEEG
                     VSESKREKVNNLDVIQDDKKLIEGYVAIVKDMALKYGISSDLSKN"
     gene            complement(5520..5714)
                     /locus_tag="KR231_002960"
     CDS             complement(5520..5714)
                     /locus_tag="KR231_002960"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0005319.1"
                     /translation="MKFVYVKIFNNWIDITDIGSINGCNAIEYINENLDKMYSSNYVS
                     INYKDKNYCIHPSCIQIVTK"
     gene            complement(5870..6088)
                     /locus_tag="KR231_002961"
     CDS             complement(5870..6088)
                     /locus_tag="KR231_002961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016056353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBH0005320.1"
                     /translation="MTKFKDNIKLVRKQMNMTQKQFASLFGISERAYQYYEAGSREPN
                     LETLILISNKLNVSTDFLLGLSPNQNRN"
     gene            6201..6395
                     /locus_tag="KR231_002962"
     CDS             6201..6395
                     /locus_tag="KR231_002962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016056354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBH0005321.1"
                     /translation="MKINNNLKLQREKIGLTQLEVAQKAKITERSYQYYEAGERLPNI
                     RTALKIAIILNTNCEKLFNE"
     gene            6437..7231
                     /locus_tag="KR231_002963"
     CDS             6437..7231
                     /locus_tag="KR231_002963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015994369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage antirepressor KilAC domain-containing
                     protein"
                     /protein_id="HBH0005322.1"
                     /translation="MNNLQLNNKNTITTLEIADMLEIRHWEVLRKLEGTEKTKGIIDI
                     LNDNNFVVVDYFIKSTYLDSKNESRPCYNVTKLGCDFLANKFTGEKGIIFTARYVRRF
                     NEMERVLKEQQPKLPTTYKEALQQLLVEVEEKEQLQLENQEKDKVIQLQQPKVLFADA
                     VSASNNSILVGELAKLIKQNGVDIGQNRLFTWMRENGYLIKRKGEDYNIPTQKSMNLR
                     IMEVKKRVINNPDGSTKVTRTVKITGKGQVYFVNKFKSSKQLSMLS"
     gene            7288..7497
                     /locus_tag="KR231_002964"
     CDS             7288..7497
                     /locus_tag="KR231_002964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0005323.1"
                     /translation="MENKKIEEIEKRITMLENQLQAQLFSQITAQSNSDFIDYMYQCI
                     VLYLHEMNKSEKRKISEITKERIRK"
     gene            complement(7507..7881)
                     /locus_tag="KR231_002965"
     CDS             complement(7507..7881)
                     /locus_tag="KR231_002965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0005324.1"
                     /translation="MQFSNNISKELQESIRKTVSDTSNTEYFYYAEFQYKIILKSIEE
                     FEKELDDEHEIALKLTNFGKDVLMIVEEVGYHNPCLIHYYGIVNGVYSEILQHTSQIN
                     FMITSVKKTDPSKPARRIGFIL"
     gene            7957..8154
                     /locus_tag="KR231_002966"
     CDS             7957..8154
                     /locus_tag="KR231_002966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBH0005325.1"
                     /translation="MLIGDNIKQILRKRDIKPYKLAKELNIDVSGLYKLLKNKNSNPT
                     IDTLIKLADYLDITLDELVGR"
     gene            8185..8577
                     /locus_tag="KR231_002967"
     CDS             8185..8577
                     /locus_tag="KR231_002967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBH0005326.1"
                     /translation="MDISESITKQFSDSLKSLIEIEINKQETDRVKSQTVEQKVKVLE
                     PKDIVVLIKRGYPNYLITVEEARGILKLDTVFMRRLVSTGLIKSLARGDGRKISRYEV
                     DDFIERNQGKNLDELLKVAERGDEIVKP"
     gene            8564..8707
                     /locus_tag="KR231_002968"
     CDS             8564..8707
                     /locus_tag="KR231_002968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0005327.1"
                     /translation="MLSLNTNKNNIVTLKKDGKAIADIVFKDIKTGKKISVGVLNKKV
                     LVK"
     gene            8874..9116
                     /locus_tag="KR231_002969"
     CDS             8874..9116
                     /locus_tag="KR231_002969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0005328.1"
                     /translation="MEAARLIAIGQIKQAEKEICKLQGTKNNSSLMWWEAVKFASQNI
                     LEGLEHDIELEASIEFREAMMYQEELEKDRPIDVQI"
     gene            9195..9476
                     /locus_tag="KR231_002970"
     CDS             9195..9476
                     /locus_tag="KR231_002970"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0005329.1"
                     /translation="MKTKNEIIKGLEDRLFLLRFTTVDEVDWDVKFGQISALEFCIDK
                     HRKGCTLEQFKEHLDEYKLQGNYGDYIDGFVSVLERNIREMEGEIDGSE"
     gene            9463..10101
                     /locus_tag="KR231_002971"
     CDS             9463..10101
                     /locus_tag="KR231_002971"
                     /inference="COORDINATES: protein motif:HMM:NF016302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ERF family protein"
                     /protein_id="HBH0005330.1"
                     /translation="MEVNNIYIKLMDVRIKFNKLDIKKSGQNKFANFKYFELADFLPQ
                     ATELLQEAKLCPIVTFTNDYATLTLINGEKPTEEIIFTSPMRELQLKGSNELQALGGI
                     ETYQTRYLYIQLLNITENDTFDATSGKEDYKRNDLTNSSIKASENGQIKISQNQIKRL
                     FSIGNTIGKDSDRVKSEVYYKFNKEVKDLSKQEYDQICVGYEKLQREKGIIK"
     gene            10111..11006
                     /locus_tag="KR231_002972"
                     /pseudo
     CDS             10111..11006
                     /locus_tag="KR231_002972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894692.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DnaD domain protein"
     gene            11026..11445
                     /gene="ssb"
                     /locus_tag="KR231_002973"
     CDS             11026..11445
                     /gene="ssb"
                     /locus_tag="KR231_002973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HBH0005331.1"
                     /translation="MNQVVLVGRLTRDPELKYIPGTGTAVASFTIAVDRNYINKEGKR
                     DTDFIPIEVIGKSAEYCANYITKGKLVALEGNIRVDNYQTQSGEKRIFTKVSTKSVQS
                     LESKNKSSNSYKESVQDGTIGLDPQGFEIIDDDELPF"
     gene            11475..11837
                     /locus_tag="KR231_002974"
     CDS             11475..11837
                     /locus_tag="KR231_002974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015994375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0005332.1"
                     /translation="MFKVERYFSGSVVDNLIEDDLTCRNYLALYCCLLGITKNGKKIY
                     PKPEKMLAEFGVKKDRKIKKELPVRIRNVNTGEVKEFESIDGAACFLRLKYQAVYQAI
                     KKKTKTRSGWKVEYIKEE"
     gene            12071..12922
                     /locus_tag="KR231_002975"
     CDS             12071..12922
                     /locus_tag="KR231_002975"
                     /inference="COORDINATES: protein motif:HMM:NF012372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA cytosine methyltransferase"
                     /protein_id="HBH0005333.1"
                     /translation="MNVLSLFDGISCGQVAFERARIKVENYFASEIKEIAIKVAMNNY
                     PKTIQLGDVRELNVSKIPKVDILIGGSPCQNLSKGRLIANKIQDGLTGDKSNLFWEYI
                     RILKQLNPEYFLLENVVMPKKDENMISQLLGVEPIKINSNLVSYQNRDRLYWTNILNV
                     QQPKDLKISFQDYKDTSFDYCKEFEIKKTPSREKMWGNGLNGNCKNVTYEDKINCVTL
                     KQDRFSNSGLVEFGSFCRYLTTRELELAQTLPVGYTKGLSIRQAQNVIGDGWTIDVIA
                     HILSNIN"
     gene            13239..13436
                     /locus_tag="KR231_002976"
     CDS             13239..13436
                     /locus_tag="KR231_002976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009899200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0005334.1"
                     /translation="MNKFQKAVSQMVKQEEKENLLQGYENCIVGRSISSSIRRYVKGF
                     EKFGYSVHEVYEFINDINKYE"
     gene            13463..13879
                     /locus_tag="KR231_002977"
     CDS             13463..13879
                     /locus_tag="KR231_002977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003366126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1064 domain-containing protein"
                     /protein_id="HBH0005335.1"
                     /translation="MSKYNNKKIVIDGIKFDSKDESEYYLYLKEKKENGEIKDFGLQQ
                     KFELQPKFKKDGKSYRAITYTIDFAIYKWNGEVVYIDVKGYSTQQGELRKKLFDYKYQ
                     DKKLIWIAKSKKYGVDGWIEYSELKKKRKENKKKVA"
     gene            13898..14398
                     /locus_tag="KR231_002978"
     CDS             13898..14398
                     /locus_tag="KR231_002978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016056376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0005336.1"
                     /translation="MASKVKKEFFMATKKHLENYKQLHINIESLKLQIKNLKEFHLGD
                     FMQGLSYDSIPISKTNSISNQVENELINLEEKIIEKQIELYEMEALKYTIDVSISNLK
                     PIHKQIIRYRYIEGLEWSLIVDKVYLEERQLRERANQAISSISIALFGKKALIEQEPL
                     FKMLDL"
     gene            14820..15026
                     /locus_tag="KR231_002979"
     CDS             14820..15026
                     /locus_tag="KR231_002979"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0005337.1"
                     /translation="MNRFEGIYSFAEATKLWDLKDSTLRKAVATGKLVENIDCKKFGR
                     DWVVTIEAMEREYGKLNNIMKDLD"
     gene            15515..16702
                     /locus_tag="KR231_002980"
     CDS             15515..16702
                     /locus_tag="KR231_002980"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0005338.1"
                     /translation="MLNEKNLKNIKNILQMVQMKHLKDFENWGINKRKKETAINSLIN
                     IIQNDGEKLDYFKEWISIFTIDGHNNYYVFNYNDSDLELEDLKNIVEDIVSENLLEID
                     TSDLEETKVIYKKNDVINKRLIIRFISPALISCKNENENGNIESGLEKTFYFATLFLD
                     LSLKQIIVSIPHTVGIKSIDNIEAKARDFSEIAKYYVSKLEDLLTTYNIQIEKYNDWI
                     YDATYELAEEGSAHNNPEINKKYEENIDKIDEFAKKIAIASGITDKAIIENFKEGVGI
                     LYENILIDEFGVVEDENQYSTFVQNGDGVNSYCRVGSKTATLKSGKGHAIAKTSRNNE
                     DVKNLGVMKSFNGTLSRFLIEVLDKELYLIRTDTSKFIEERVIYDVIRKVGEYKYTFR
                     KSE"
     gene            16647..17033
                     /locus_tag="KR231_002981"
     CDS             16647..17033
                     /locus_tag="KR231_002981"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0005339.1"
                     /translation="MMLYEKLENISILLGNQSKAKSIIEELEKLMKSDIITPRLLARK
                     TKVTLLEATRVLEFLVKENELEFFIVVECSNPDSVYENEIGHYKYFTSIKEFNAFSKG
                     QECPICGCGYKYNFEDTKIGFRRLEK"
     gene            17038..17808
                     /locus_tag="KR231_002982"
     CDS             17038..17808
                     /locus_tag="KR231_002982"
                     /inference="COORDINATES: protein motif:HMM:NF016362.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease"
                     /protein_id="HBH0005340.1"
                     /translation="MSLDTLKEYLSICDDNLIWEPFYDDSMLLDEFSNYIKEIELSKE
                     WNKSKNHEKGKILEQLVRFIMSRFTILSDISVNKSTTDNELDVFVKFNDNIPIPFLCN
                     IKSKIVCECKNWKSRKVDVGMVSKLAEICNKNNAGLGIFISLNGLTGKGWQYAEGKRR
                     KLYLSDKMPIISFTVDEITKLKYKRYNLLTMIKCKMQALIDEMEFAGGELRLLESELG
                     FIDCLNENIESLKMLGLITEVEYNNIKVRINHRYDIVN"
     gene            17866..18549
                     /locus_tag="KR231_002983"
     CDS             17866..18549
                     /locus_tag="KR231_002983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBH0005341.1"
                     /translation="MQDVKEKVKQDYLKGMKQKEISAKYDISLNTLKSWIKRYNWANE
                     KKKGAPKNKRGAPIGNKNATGPPGNKNAEKFGFFSKYLPEETQDLINEIKDKDKFDIL
                     WEQITIQYAAIIRAQKIMYVKDKEEMIKELKKYESTENGEKIEYEFQFAWDRQASFLN
                     AQSRAMSELRSLIKQYDEMIHKDWNLATEEQKTRVEKLKCEVDNLSKDDIGDDELKIS
                     VDYGDRNDS"
BASE COUNT         7697 a         2008 c         3172 g         5702 t
ORIGIN      
        1 cacttgtagc gtgtgaatta ataacatgta ttatttcttc ttctgttata agaaattcac
       61 atgcccattt tagtgctttg ttttcagttt tgtctatcaa gattttattt ttgtaactgt
      121 tttttgaaga tacatagttt ccaacactgg taaaatgatg tcctaattct tctgctaaga
      181 tttctattag tttagcattg ttttgtttta atgaattaag taatgatata atttttagtc
      241 cttgtctgtt tatatacaat ccttttatgt catctgctat tttgtcagtg tagtaaattt
      301 ctatctcttc attatttgct aagtctaaaa gtgcgtctag tttgttcatt gaaatccccc
      361 tataaaaaga atgtattttt gatttttgtt atatataaag agcaggtgtg aactgctcta
      421 aatattcatt ttttatccaa aaaagattgg ataattttag ctgtagacaa aatatggatt
      481 atagtatatg attataatat aattacatat aatatatgta agcacttaca aatgtgtgtt
      541 agtatagtta gcactaaatt tgtatttgtg cttaaagcga ttaaaggagt tttggagcgg
      601 tgggtagagt tttactcact ataaccaaga ctcttttgca tattagagta tttcatgtag
      661 tcatatattc taataagcct tcttaaattt gttttttcgc ttgtttttgc agactctaaa
      721 atattaggat tttcctcaaa tattttctta agtagatttt ctaactgttc agtgtcaatt
      781 tctttttctt ctaaaaaagc aataagtctt gtagcttttt caaatgattg atgttcatca
      841 ttccaaatac cataaacact tctatttttt atgtaagtat tatttctatt ttttttaata
      901 ctattgctaa taatattttc aaagtcactt tctagtgcaa ttgtcctata atctggaaat
      961 tcaagtgtgc tattaaaaag atgtttattt aatggtaatt tattatattg cttaattaaa
     1021 gatggataag catattcaag taattcatct gatgaaaatt ctaagtcatt catgactata
     1081 tcacgatacc attcatcaaa acttaatcct tttaatcctt taagaccaaa atcacttgcc
     1141 ttgccaactg ctaaaactaa atcttcatct tttattcttg tatcatcaac actaccaacc
     1201 cgaattttag cagtaggttt gttagtaatt gtgaaatcgt aaaattcttg tttgaacatt
     1261 cttaatattc taactggtaa ttttgatttt ttttcagata atgcctcata gagtaaatta
     1321 aaatcctcca gtttaatttt agtcatagta atcattttat tatcaaaaac aattgtatga
     1381 cttgatattt ctatatcatt aaagtttttt tcatactcaa tgaatatgaa acgttcctcg
     1441 agttttttag cattttcatt agatagacaa ttaactatag cattaagtat tttttttata
     1501 tttacatctg taacagagta accaataaat atgataggaa actcaacaaa tatagtcatt
     1561 agcttagctg ccaagtaggc acttttgctg tcaaagtcta tataatcagc ttcatttatt
     1621 acaatactat ttggagaaga aacacatcca tgaattttat aaatttctgc aataccttgt
     1681 atagatgaaa aaactaaatt ttcttgacct atatatgttg tataattatc aacgatagtt
     1741 tccaaaaaac aatcataatt tgttgtaata aatcctgata aacttttttt agagatatta
     1801 ctaagttttt caacttcatc ttgatattta tctactattt tagaattatt tttaatatac
     1861 atagcaattt ctgccttaaa tggagaaact cctgatttaa caatatctaa atacttagag
     1921 tctaagcttc gtatagaaga atctgaaaac cattttttat taaaatcatt ttcaataagt
     1981 tctgcaattc taggatttat acccattttt gggttctctg attttgcttt atttttataa
     2041 cttgtatata taaagtcatc attactaatt ttttctgcaa agacttttag taaatcctcc
     2101 caatttggaa gattatagta tcttctagtt aaaccagaac caacaaataa aaatggtgta
     2161 gcattaaatc ggtttatgac atctgatatt atagatttca tataatttat cacctacttt
     2221 taatttattt tttatactta tttattaaaa attcaatata atcattgagt tgttcttgag
     2281 cttcctctgg taaatctttg tgaggattaa ctctatgtgc agctacagtg tctatatcat
     2341 tttttacaat agacctacct aataaataat cagtagtcac attaaatatt tcagcaaggc
     2401 tagatagcat ataagcatca ggaactgtct ttccttgttc ataataacca taagcgcttt
     2461 tggttaagtt taatttattt gcaacatctt cttgagtcat atttttttca gctctaagtt
     2521 cttttagtct tttttgaaat aatgtattat tacaagaagt tttgctagaa atattgcttg
     2581 ctttattatc atacctacct attaaataat caacagtagt gccaaaatat tcagctaaac
     2641 tagataacat ttctggggta ggtgttcttt taccttgttc ataaaatcca tatgcactag
     2701 tagttatgtt aagatagttg gcaatttctt tttgcattac acctttttct ttcctaagaa
     2761 atttcaatct atctgataaa atgctcatat aatcactcct cttaataaag ttgcctttat
     2821 taaataatac aacaaatagt tgtaaaatga aataaaaaaa taaaaaaact atttacaaac
     2881 aacatatagt tgtgtattat ataagtataa acaacaaaat gttggtaagg aggatatagc
     2941 ttgaacaatc taaaggaact taggacagaa aggaatttaa agcaaaaaga tgttgcatta
     3001 aaagtaggta taactactag ttattatgga atgattgaaa gtggaacaag agtaccaagt
     3061 ttagcaatag caataaaatt atctaaatgt tttggagtat caatagaaaa aattttttta
     3121 aatacaaata caacaagatg ttgtttaaaa gagaggagtt aaatatgaaa gatttaaaaa
     3181 tagtaaaagt taataataaa ctaacaactg acagtagaga tatagctcta atggttgaaa
     3241 aagaacacaa gattttacta agggatataa gaaattatat aaaccaaatg gaagaagcca
     3301 ataaaaacat gagtacagat ttgtacccat ctgattattt tattgaaaat acttatttag
     3361 atgattataa aagagagaag ccatgctatg caataacaaa gataggttgt gacttcatag
     3421 caaataaaat gacaggcata aaaggtacgg catttacagg aatatataca aaaaaatttg
     3481 aagaaatgga gcaagtatta aaaaatgaac aacctaaact accaactaca tataaagaag
     3541 cattacaaca tcttatagag caagtagaag taaatgagaa attacaacta gaaggaaaaa
     3601 tgaaagacca agtaataaaa gaactaaaac caaaggcaga ttatacagat atgatactta
     3661 aaaacaaagg acttgtcaca ataactcaaa tagcaaaaga ctatggaatg agtggaaaag
     3721 aaatgaataa aatacttcat gaaagaggga ttcaatataa acaaagtgga caatggcttt
     3781 tatataaaca acaccaaggg aagggataca ctcattcaga aacaatagac ataactagaa
     3841 gtgatggaat gactgatgta aaaatgacaa ctaagtggac tcaaaaggga agattgtttt
     3901 tatatgactt attaaaagta aataacatat taccagatat agaaaaagag tatagttatc
     3961 aaacttcaat gttatgttag tactttgaaa aataaataca gaatattcaa aaagaggtga
     4021 tttaaaggtt gagtaataga aagaagtata ccttgagtat tacgaaagaa ttatacaata
     4081 aatgtaaaga aaaagctaat caaagaggta tgtcagtgaa tgattacata ctatcagtga
     4141 ttagcaagag tatataaatt attcttcaat attaatttta atttctcctt ttctttgctc
     4201 ataatcttca atatgttttt ttattatttg ttcaatttcc ttattagcag aacgaccttc
     4261 gctttcagct atatatttaa ttttttcaag cagaactctg tttattctta aagtgtattt
     4321 aggtagtgaa gttgacataa taatacctcc tttttaaagt ctaaatgatg tcataattat
     4381 atcataaaaa taatttatag aaaatctata aaatatattg acggcataaa gacggcgtga
     4441 tattattaaa acaagaaagg ggttgacggc aaaatgaact caaataaaaa gagaataact
     4501 gttaggatgc cagaaaaatt aaatgaagaa ataacgaaaa aatcaaaata cttagggtta
     4561 actaagaact catttatatt agatatacta tggaaggaat ttgagttatt agaatataga
     4621 agttataaaa aggaggtaga taaacatgaa taacttacaa gtaatagaaa gaaataatga
     4681 gagagttcta actacacaac aattagcaga tgtatatgaa actgactcaa gaaatataag
     4741 taacaatttc aacaataaca aagataagtt tattgaaggt aaacattatt ttttattgca
     4801 aggtgatgat ttaaagaatt ttaaaggcat tcatacagaa tatgaaaacc taaaatttgc
     4861 ttcaaaaatg tatctttgga ctgaaagagg agcaaataga cactgcaaaa tattagatac
     4921 agataaggct tgggaacagt ttgataattt agaggaaaca tatttcaaag ttaagcaaca
     4981 taagccaact tgtatagaag atgtattaat agaaagttta aaagaaatga aagatttaag
     5041 acttcaagtt aatcaagcaa atagcattgc tttagaagca aagacagagg ttgaaacaat
     5101 aaaagatgta gtttcattag actcaaatag ttggagaaca aatacacatc aactaattgc
     5161 aagaatagca aaaaaacaag gtggttttga acatataaat atgcttagaa cagaaagtta
     5221 tgaattatta aataagagat ttggagttga cctacataga agattgatca ataaaagaag
     5281 aaaaatggca gaagaaggtg tatctgaatc taaaagagag aaagttaaca atttagatgt
     5341 aatacaagat gataagaaac tcatagaagg gtatgttgct attgtaaaag atatggcttt
     5401 aaaatatgga atatcaagtg atttaagcaa aaattaagtt aaatcacaac agcactttga
     5461 aaactaaata taaaataaaa atatctccct taaaagtttt ttaaagagag ataaacactt
     5521 tattttgtaa ctatttgaat acatgatgga tgaatgcaat agtttttatc tttgtaattt
     5581 atagaaacat aattactaga gtacatttta tcaaggtttt cattaatata ttcaattgca
     5641 ttacagccat ttatagagcc aatatcagtt atatcaatcc agttattaaa tatcttaaca
     5701 taaacaaact tcatgataac accaactttc attagaattt aagttaatta taacatggtg
     5761 tactgagata atgtgttaag aaatagatac agaatattca aaagaggtga ttagatggaa
     5821 atagagcaaa caacaatacg cctgctaaaa agcagacgaa agttgaatat taatttctat
     5881 tttggttagg cgaaagacct aacaaaaaat ctgtagatac attaagtttg ttagaaatta
     5941 atattaaagt ttctagattt ggttctcttg aaccagcttc ataatactga tatgcacgtt
     6001 ctgagatacc aaacaaacta gcaaattgct tttgagtcat attcatttgc tttcttacta
     6061 gcttaatatt atctttgaat ttagtcataa ctacacgctc caataaaaaa ataaataaat
     6121 ttcttgacac gaacaatatt agcgtgtaat atataaaaca tagcacgaac aatattggcg
     6181 tgttaaataa aaaggagagg gtgaaaataa ataataattt aaaactacaa cgtgaaaaaa
     6241 ttggcttaac acaattagag gttgctcaaa aagccaaaat aacagagaga agctatcaat
     6301 attatgaagc tggcgaacgt ctcccaaaca ttcgtacagc tttaaagata gctataattt
     6361 taaatactaa ttgtgaaaaa ctctttaatg aataatagca taaaaggact cagattacaa
     6421 gaaaggagct ttagatatga ataatttgca acttaacaat aaaaatacaa taacaacatt
     6481 agaaattgct gatatgttag aaatcagaca ctgggaagtc ttaaggaaat tagaaggaac
     6541 agaaaaaaca aaaggaatta ttgatattct taacgacaac aattttgttg tggttgatta
     6601 ctttataaaa tcaacatatt tggattcaaa aaatgaaagt agaccttgct ataatgtaac
     6661 aaaattaggt tgtgactttc tagcaaataa atttactgga gaaaaaggta ttatttttac
     6721 agctagatat gtaagaagat ttaatgaaat ggaacgagta ttaaaagaac aacaacctaa
     6781 actaccaact acatataaag aagcattgca acagttatta gtagaagttg aagaaaaaga
     6841 acaattacaa ttagaaaatc aagaaaaaga taaggtaatt cagttacagc aaccaaaagt
     6901 actgtttgct gatgcagttt cagcttcaaa caattctata ttagttggag aacttgcaaa
     6961 acttataaaa caaaatggag tagatatagg acaaaacaga ttatttacct ggatgcgaga
     7021 aaatggatat ttaattaagc gtaaaggtga agattataat attccaacac agaaaagtat
     7081 gaatctaaga ataatggaag ttaaaaaaag agtaattaat aatcctgatg gaagtactaa
     7141 agtaactaga acagtaaaaa taactggaaa aggtcaagtt tattttgtta ataagtttaa
     7201 aagtagtaaa caattatcaa tgttaagtta aatcataaca gtaccttgaa aactaaatac
     7261 agaatatttt ggaaaggaga gattgaattg gaaaataaga aaatagaaga aatagagaaa
     7321 agaataacca tgcttgaaaa tcaattgcaa gcacagttat ttagtcagat aacagctcaa
     7381 tcaaatagtg attttataga ttatatgtac caatgtatag ttttgtattt acatgagatg
     7441 aataaaagtg aaaaaagaaa aattagtgaa attactaaag aaagaatcag aaaataagaa
     7501 tgataattac aatataaaac ctattcttct agcaggtttt gaagggtcag ttttctttac
     7561 tgaagttatc ataaagttta tctgtgatgt gtgttgaaga atttcagaat aaactccatt
     7621 tactatgccg tagtagtgaa ttagacaagg gttatgataa cctacttctt caacaatcat
     7681 taatacatct tttccaaagt tagtcaattt tagtgcaatt tcatgttcat catcaagttc
     7741 tttttcaaat tcctctatag atttaagaat aattttatat tgaaattcag catagtaaaa
     7801 atactctgtg ttagaagtat cagagactgt ctttcttata ctttcttgta attctttaga
     7861 tatattgttt gaaaactgca taatacacca tccttttgaa aattttggaa tttattccat
     7921 gtttatatta taccatgtag aactgaggtg aatacaatgt taataggcga caatataaag
     7981 caaatactaa gaaaaagaga tataaaacct tataaattag caaaggaatt aaatatagat
     8041 gtaagtggtc tatataaatt gttgaagaat aaaaattcta atccaactat agatactcta
     8101 ataaaattag ctgattattt agatattaca ttagacgaat tagttggaag ataaatattt
     8161 gaaaagaggg gagagaattt taacatggat atttctgaaa gtataacaaa gcaatttagt
     8221 gatagtttaa aaagtttaat agaaatagag ataaataaac aagaaacaga tagagttaag
     8281 agtcaaactg ttgaacaaaa ggtaaaagta ctggagccta aagatatagt tgttttaata
     8341 aaaagaggtt atccaaatta tttgataaca gtagaagaag caaggggaat tttaaaatta
     8401 gatacagttt ttatgcgtag gttagtgagc acaggtttga taaaatcact ggctagaggt
     8461 gatggtagaa aaatttcaag atatgaagtt gatgatttta ttgaaagaaa tcaaggtaaa
     8521 aatttggatg aacttttaaa agtagcagag aggggggatg aaattgttaa gccttaatac
     8581 taataagaat aatatagtaa ctcttaaaaa agatggaaaa gctatagcag acatagtatt
     8641 taaagatatt aaaactggta agaaaatatc ggttggagta ttaaataaaa aagtgctggt
     8701 caaataacca acacacaaaa aaataaaaaa taaaatataa cacaaacaaa ttatagcaca
     8761 aaaagaatgg atttagaata ggtaatataa cattctaaaa ggtttaatgt gtaataattg
     8821 taacaattta gaatgtagct tatatagata gtaataaatt gggagggatt taaatggaag
     8881 cagctagact aatagcaata ggtcaaatta aacaagcaga aaaagaaata tgtaaattac
     8941 aaggtacaaa aaataatagt agtttaatgt ggtgggaagc cgtaaaattt gctagtcaaa
     9001 atatattaga gggtcttgaa catgacattg agttagaagc ttctattgag tttagagaag
     9061 ctatgatgta tcaagaagaa cttgaaaaag atagaccaat agatgtccag atataaaaaa
     9121 agagccttcg cacaggctct aagtgaaaat aagttacaaa aattataggt atattataac
     9181 ataaggggga ataaatgaaa acaaaaaatg aaataattaa gggtttagaa gatagattat
     9241 ttttattaag atttacaaca gtagatgaag tagattggga tgtaaaattt ggacaaatat
     9301 cagcattaga attttgtata gataaacata gaaaaggatg cactttggaa caattcaaag
     9361 aacatttaga cgaatacaaa ttacaaggga actatggtga ttatatagat ggttttgtgt
     9421 cagttttaga aagaaatatt agagaaatgg agggagaaat tgatggaagt gaataatatt
     9481 tacataaaat tgatggatgt aagaattaag tttaacaaat tagatataaa aaagagtggt
     9541 caaaacaagt ttgctaactt taaatatttt gagttagcag acttcttacc tcaagcaaca
     9601 gagctgttac aagaagctaa attatgccct atagtgacct ttacaaatga ttatgcaact
     9661 ctaacattga ttaatggaga gaaaccaaca gaagagataa tatttacttc tccaatgaga
     9721 gaattacaat taaaaggctc taatgagtta caagcattag gaggaattga aacatatcag
     9781 acaaggtatt tgtacattca gttattaaac attacagaaa atgatacttt tgatgctact
     9841 agtggaaaag aagattataa aagaaatgac ttaacaaact cctctattaa agcaagtgaa
     9901 aatggtcaaa taaaaataag tcaaaatcaa ataaaaagat tgttttcaat aggaaataca
     9961 ataggcaaag attcagatag agtaaaaagt gaagtgtatt ataagtttaa taaagaagtt
    10021 aaagatttaa gtaaacagga atatgaccag atatgtgttg gatatgagaa attacaaagg
    10081 gaaaaaggaa taattaagta ggtgaatttc ttgaaggaca gagacaaagc aactatagag
    10141 aaaggaaata tacttagtga tgggtatggt ctttcaccac aattggtagc tagagattca
    10201 tggctaacaa caggagcaag agctttatat ttctatctat ccagttttgc aggagcaagt
    10261 gggacatgtt atccatctag ggatattatg actcatgaac ttggtataaa taaagatact
    10321 tttagtaaat acctaaatga actaaagacg agtggttata taaaagtata taaaaataaa
    10381 actagggaag gaaggatgca aaataatata tatgaggtag tatttgatag aagctatata
    10441 gaaagtcata tatccattag atgtaagaaa gaaaataaaa aaaaccatgt ccgaaaaaag
    10501 cagacatgga accatgtccg aatttaccgg acatggttca accggacatg gaaaagtcgg
    10561 acactataag taacagtatt ataaataaca gttttaaaag tagtatgtat atagagcaag
    10621 ctgtggataa ctctttaaaa gaatttaaga agctatatga agaaaatata ggagtagtat
    10681 atccagtcac agctgaatgg ttattagaag tatctaatga agtagatata agagtattta
    10741 aaagagctat agagatatgt gctgaaagaa tgaatatgaa tttatcatac ttaaaaggaa
    10801 tccttaaaaa gtggaaggat gcaaatataa ctacatatga acagttagaa tcatataaat
    10861 tacaacatga aaataaaaag tcaaaaaaaa ccaatagtgt agtaagcaaa aataagtttg
    10921 ctaattttga acaaacattt actcaataca gtaacaaaga attagatgaa attataaaga
    10981 aaagccaaaa ggctaaattt aaataatatt gatggaggta ttaaaatgaa tcaagttgta
    11041 ttagttggaa gattaactag agacccagaa ctcaaataca taccaggaac aggtacagca
    11101 gtagcatcat ttacaatagc tgtagacaga aattatataa ataaagaagg aaaaagggat
    11161 actgatttta taccaataga agtaataggt aaatcagctg aatactgtgc aaattacata
    11221 acaaaaggga agctagtagc attagaaggg aatataagag ttgacaatta tcaaactcaa
    11281 tcaggtgaaa aaagaatatt tacaaaagtc agtacaaaat cagtacaatc attagaaagc
    11341 aagaataaat cgagtaattc atataaagag agtgtacaag atggaaccat aggactagac
    11401 cctcaaggat ttgaaattat agatgatgat gagttaccat tttaatctga aaaattaaat
    11461 atgaggtgaa ataaatgttt aaagtagaaa ggtattttag tggctcagta gtggacaacc
    11521 ttattgaaga tgaccttaca tgtagaaact acttagcatt atattgttgt ttgttgggaa
    11581 ttacaaaaaa tggaaaaaag atatatccta agccagaaaa aatgttagct gagtttggag
    11641 taaagaagga cagaaaaata aaaaaagagt taccagtaag aattagaaat gttaatacag
    11701 gggaagtaaa agaatttgag tctatagatg gtgcagcctg ttttttaaga ttaaaatatc
    11761 aagcagttta tcaagctatt aaaaagaaaa ctaaaacaag aagtggctgg aaagttgaat
    11821 acattaagga ggaataatgg aagtttcaag gacagaatat acaattaaaa gagcaaaaga
    11881 gttatatgac aatggagagg atatatttat tgctatagat aaggctagag aaaaatatga
    11941 ggagatgatt aaaagtgaat atcttagcta gtgtgatatt agtaatagga agttttatag
    12001 ctggtagagt ttatgagtat agattgaacc taaaagggtg tgaaaattgt gataataaga
    12061 aggtgcaaat atgaatgtat taagtctatt cgatggaatt agttgtggtc aagttgcttt
    12121 tgagagagct agaataaaag tagaaaatta ttttgcaagt gaaataaaag agattgcgat
    12181 taaagtagca atgaataatt acccaaaaac aatacaactt ggagatgtaa gagagctaaa
    12241 tgtaagtaaa atccctaaag tagatattct tattggcgga agcccatgcc aaaatttaag
    12301 taaaggaaga ttaatagcta ataaaataca ggatggatta actggagata aaagtaattt
    12361 gttttgggaa tatataagaa ttctaaaaca attgaatcca gaatattttc ttttagaaaa
    12421 cgtagtgatg cccaaaaaag atgaaaacat gataagccaa ttgttaggag ttgaaccaat
    12481 caagataaat agcaatttag ttagttatca aaatagagac agattatatt ggacaaatat
    12541 tttaaatgtt caacaaccta aagatttaaa aattagtttt caagattata aagatactag
    12601 ttttgattat tgcaaagagt ttgaaattaa aaaaactcca agtagagaaa aaatgtgggg
    12661 taatggttta aatggaaatt gtaagaatgt aacatatgaa gacaaaataa actgcgtaac
    12721 attaaaacaa gatagattta gtaattcagg tttagtagaa tttgggtctt tctgcagata
    12781 cttaacaact agagaattag agttagcgca gacgctacca gttggatata caaaaggttt
    12841 gagtataaga caagcacaaa atgtcatagg tgatggttgg acaatagatg tgatagcaca
    12901 tattttatca aatattaact agttctttat atataaatta ttattgaagc ggttagctat
    12961 catgatactt gtagcagtaa gttttatagc tggtagggtt tatgagtata gattgaatct
    13021 gaaagagtgt gaaaattgta ataacaacta tcctgaaaaa tgagaaagaa gtggttttat
    13081 gaataaaaga ataatttgca attggtgtgg taaattattt tacatcccaa aacagtctaa
    13141 aaaaatttac tgttgtaaaa gatgtgagag aaaggctaag aaaagcaata gagaacagca
    13201 aaattaattt taaacaataa aactatgggg gaatagcaat gaataagttt caaaaagcag
    13261 tttctcaaat ggtgaagcaa gaggaaaaag aaaacttgtt gcaaggatat gagaattgta
    13321 tagtaggtag aagtatatca agttccataa gaagatatgt aaaagggttt gaaaagtttg
    13381 gatatagtgt acatgaggtt tatgaattta taaacgatat taataagtat gagtaacttt
    13441 aagtgataaa ggaagtattt gattgagtaa atacaataat aagaaaattg taatagatgg
    13501 aattaaattt gatagtaaag atgagtcaga gtattattta tatttaaaag aaaaaaagga
    13561 aaatggagaa ataaaagact ttggacttca acaaaagttt gaactacaac ctaaatttaa
    13621 aaaagatggg aaaagctata gagctattac atatacaatt gattttgcca tatacaaatg
    13681 gaatggtgaa gtcgtttata tagatgtgaa agggtatagt acacagcagg gtgaacttag
    13741 aaaaaagctt tttgactata aatatcagga caaaaaattg atatggattg ctaaaagcaa
    13801 aaaatatggg gtagatggtt ggatagaata tagtgaactt aagaaaaaga gaaaagaaaa
    13861 taagaaaaag gtagcttaaa taaataggag tgatgttatg gcaagtaaag ttaaaaagga
    13921 gttttttatg gcaactaaaa aacaccttga gaactacaaa caactacata ttaatattga
    13981 aagtctaaaa cttcaaataa aaaatctcaa agagttccat ttaggtgatt ttatgcaagg
    14041 tttaagctat gacagcattc ccataagtaa gactaattca ataagtaatc aagttgaaaa
    14101 tgagttaatt aatcttgaag aaaagataat agaaaagcag atagaattat atgaaatgga
    14161 agcgctaaaa tatacaatag atgtatccat aagtaattta aaacctatac ataaacaaat
    14221 tataaggtat aggtatattg aaggcttaga atggagttta atagttgata aagtatactt
    14281 agaagaaaga caattaagag aaagagctaa tcaagccatt agttcaatat caatagcctt
    14341 atttggtaaa aaagcattaa tagagcaaga accattattt aagatgttag atttataggc
    14401 agttaataac tgtctatttt ttttgtgaaa aagatatatg gaagttattg acaatatcac
    14461 gcatacgtga tattattgaa gtatagaaag gaggcgaaaa gaaagtggct aagaaaataa
    14521 aagagttcag aaaactcata aaagaattaa ctgaactcgt actcgaagtt ggcacactat
    14581 tagcagtcat caaaatggta atagatagcc tacattagta aaatgttaag agtggaagtt
    14641 gcaccttccc tcttaactaa attataaaac atagtcacta aaaatacaat gaataagtat
    14701 agagagttaa catttgaatt attgaaacta ctgtatgaca ctattaaatt aattggagca
    14761 tcaatattgt tatattatgt tattaactca attttctagc aatgattagg aggtatttta
    14821 tgaatcgatt tgaaggtatt tatagctttg cagaagcaac aaaattatgg gatttgaaag
    14881 attctacact tagaaaagca gttgcgacag gcaaattagt tgaaaatatt gattgtaaaa
    14941 agtttggtcg tgattgggta gtaactattg aagcaatgga aagagaatat ggaaaattaa
    15001 ataatataat gaaagaccta gattaaattc taggtctttt tattgccgct tttctgccga
    15061 ttttacaatt taaaatgtga gataatagta ttgtggaaat gaatatttct ctctcaaaac
    15121 taaatatatg tgggctaggt taagggattc gcctagctta tatgaacaaa ctaggcaggg
    15181 catgaggatg ctgtaagttc aattcttact atgttcaaac ttattaatac actatatgta
    15241 gatatgctgg attaaaacgg aatttaattc aaatgtctaa aagagtgggg cttggtaacc
    15301 tcactcaatt tgcaaggact ggtgtgtaat cttaggttcg attcctaaaa cttgctccct
    15361 taaatataat atgtatcccc aaaaaaaggc ttagattaaa ttctaagtct ttttttaata
    15421 attaatgtag ataataatat ttattgctaa aatgatgtac aaatatgata atataaatta
    15481 cataaagata tataaataga gggggattat aaatttgtta aatgaaaaga atctaaagaa
    15541 cataaagaat atattacaaa tggtacaaat gaaacacctt aaagattttg aaaattgggg
    15601 aattaataaa cgaaaaaaag aaactgctat aaatagcttg ataaacataa tacaaaatga
    15661 tggagaaaaa ctagattatt ttaaggaatg gatatcaatc tttacaatag atggtcataa
    15721 taattattat gtttttaatt acaatgattc tgacttggaa ttggaagatt taaaaaacat
    15781 agtagaagat atagtaagtg aaaatttatt ggagattgat actagtgatt tagaagaaac
    15841 taaggtcata tataaaaaaa atgatgtcat aaacaaaaga ttgattataa gatttatttc
    15901 tccagcttta attagctgta aaaatgaaaa tgagaatggg aatatagaat ctggattaga
    15961 aaaaactttt tattttgcaa ctttatttct agacttaagt ttgaaacaaa taatagtttc
    16021 tataccacat actgtaggta taaaaagcat agataatata gaggctaaag caagagattt
    16081 ctcagaaata gcaaaatatt atgtatcaaa attagaagat ttgttaacta cttataatat
    16141 acaaatagaa aaatacaatg attggatata tgatgctaca tatgagcttg ctgaggaagg
    16201 cagtgctcat aataatcctg agataaacaa aaaatatgaa gaaaatattg ataaaataga
    16261 tgaattcgca aaaaagatag ctattgcttc tggaataact gataaggcta taatagaaaa
    16321 tttcaaagag ggagtgggaa tactctatga gaatattcta atagacgaat ttggtgtggt
    16381 agaggatgaa aatcaataca gtacttttgt gcaaaatggt gatggagtaa attcatactg
    16441 tagagttggg tctaaaacag caaccctaaa atcaggaaag ggacatgcta tagccaagac
    16501 atctagaaac aatgaggatg tcaagaattt aggtgtcatg aaatcattca atggaacttt
    16561 atccagattt ttaattgaag tcttagataa agaattatat ttaataagaa cagacacttc
    16621 taaatttata gaagagaggg tgatttatga tgttatacga aaagttggag aatataagta
    16681 tacttttagg aaatcagagt aaagcaaaat ctataataga agaattagag aaattaatga
    16741 agagtgatat cattacacca agattgctgg ccaggaaaac taaagttaca cttttagagg
    16801 ctacaagagt tcttgaattt ttagttaaag aaaatgaatt agaatttttt attgttgttg
    16861 aatgttctaa tccagatagc gtatatgaaa atgaaatagg tcactataaa tacttcactt
    16921 cgataaaaga attcaatgct ttttcaaaag gacaagaatg cccaatatgt ggatgtggtt
    16981 ataaatacaa ctttgaagat acaaaaatag gctttagaag attggagaag tgatacagtg
    17041 agtctagata ccttaaaaga atatctaagc atatgtgatg ataatttaat ttgggagcct
    17101 ttttatgatg acagtatgct attagacgaa ttctctaatt atataaaaga aatagaatta
    17161 tctaaggaat ggaataaatc taaaaatcat gagaaaggaa aaattttaga acaattagta
    17221 agatttataa tgtctagatt tacaatatta agtgatatat ctgtaaataa gtctacaaca
    17281 gataatgagc tagatgtttt tgttaagttt aatgacaaca taccaatacc attcttatgt
    17341 aatataaaat caaaaatagt atgtgaatgt aaaaactgga aaagtagaaa agtggatgta
    17401 ggaatggtat ctaaactagc agaaatatgc aataaaaata atgcgggatt gggcatattt
    17461 atttctttaa atggattgac aggtaagggg tggcaatatg ctgaaggaaa aagaagaaaa
    17521 ttatatttat cagataagat gccaataata tcgtttacag tagatgaaat aacgaaatta
    17581 aagtataaaa ggtataatct tctgactatg ataaaatgta aaatgcaagc attaatagat
    17641 gagatggaat ttgctggagg agaattaaga ttattagaaa gtgaacttgg atttatagac
    17701 tgtttaaatg aaaatataga atctttgaaa atgttgggtt taataaccga agttgaatat
    17761 aacaatatta aagtaagaat caatcataga tatgatattg taaactgaga actccaaacg
    17821 agttcttttt ttattcccaa aacgacaaac aaacgaggtg gtggtgtgca agatgtgaaa
    17881 gaaaaagtaa aacaagatta cctaaaaggt atgaaacaaa aggaaatatc agcaaagtat
    17941 gacattagtt taaatacttt aaagtcatgg ataaaaagat acaattgggc taatgagaaa
    18001 aagaagggtg cacctaaaaa taaaagaggt gcacccatag gtaataaaaa tgccactggt
    18061 cctcctggaa ataagaatgc tgaaaaattt ggtttcttct caaaatactt acctgaagaa
    18121 acccaagact taattaatga gataaaggat aaagataaat ttgatattct ttgggaacag
    18181 ataacaatac aatatgcagc aataataaga gcacaaaaga taatgtatgt taaagacaag
    18241 gaagaaatga ttaaggaatt aaagaaatat gaaagcacag aaaatggtga gaagatagag
    18301 tatgaatttc aatttgcatg ggataggcaa gcatcttttc ttaatgcaca gagtagagca
    18361 atgagtgaac ttagaagttt aattaaacag tatgatgaaa tgattcataa ggattggaat
    18421 ttggctacag aggagcagaa aacaagagtt gagaagttga aatgtgaagt tgataaccta
    18481 agtaaagatg atattggaga tgatgagttg aaaataagtg tagattatgg tgatagaaat
    18541 gatagttaga atagatttta atccagattt caaggaagc
//
LOCUS       DAEPHU010000076        18321 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 01A10CD0081
            SAMN05941466-rid12468953.denovo.076, whole genome shotgun sequence.
ACCESSION   DAEPHU010000076 DAEPHU010000000
VERSION     DAEPHU010000076.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941466
            Sequence Read Archive: SRR6291087
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 18321)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18321)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068158.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 22:43:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,892
            CDSs (total)                      :: 3,805
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 87
            rRNAs                             :: 8, 1, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 55
            CDSs (without protein)            :: 55
            Pseudo Genes (ambiguous residues) :: 0 of 55
            Pseudo Genes (frameshifted)       :: 21 of 55
            Pseudo Genes (incomplete)         :: 28 of 55
            Pseudo Genes (internal stop)      :: 16 of 55
            Pseudo Genes (multiple problems)  :: 8 of 55
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18321
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941466-rid12468953.denovo.076"
                     /strain="01A10CD0081"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            151..3697
                     /locus_tag="KR231_002984"
                     /pseudo
     CDS             151..3697
                     /locus_tag="KR231_002984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453516.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="diguanylate cyclase"
     gene            3882..5816
                     /locus_tag="KR231_002985"
     CDS             3882..5816
                     /locus_tag="KR231_002985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YgiQ family radical SAM protein"
                     /protein_id="HBH0005342.1"
                     /translation="MENKFLPISKQDMIDRGWEELDFVLVTGDAYVDHHSFGTAIISR
                     VLESAGYKVGIIAQPDWRTTDDFMKLGKPRLAFLVNAGNMDSMVNHYSVSKKHREKDM
                     YSPGGKMGYRPDRATIVYCNKIREAYSDVAIVIGGIEASLRRFAHYDYWSDKVRKSML
                     IDSGADLLVYGMSEKQIVEVANALNDGYDPKYIRHIDGTCYISDTLEEIYDKYILIPS
                     YKEICEDKMKYVEAFKIQYDEQDPFRGNIIVQPHGSKYLVQNKPEKPLSREELDEVYG
                     LPYQKTYHPVYEKFGGIPAIEEVKFSIVSSRGCFGSCSFCAITFHQGRAVQSRSEKSI
                     IDEAIGITNLDDFKGYIHDVGGPTANFRRPACKKQITKGACKNRQCLSPSPCKNLDAD
                     HSEYLHLLRAVRKLPKIKKVFVRSGIRYDYVMADKNNKFLRELIEHHVSGQLKVAPEH
                     ISEEVLKYMQKPAGKTYDKFRQKFFAINEELGKKQYLIPYLMSSHPGSTLNSAIELAE
                     YLRDTHYQPEQVQDFYPTPGTLSTTMFYTGIDPLTMKPVYVPKSKRDKAMQRALLQYR
                     APRNYDLVYSALVEAGREDLIGFGHRCLIKPKNEKPYFNRNNSKKNVSKGTNKNKKTN
                     TNNRSNKNQQKSSTKKKKKH"
     gene            5922..6917
                     /locus_tag="KR231_002986"
     CDS             5922..6917
                     /locus_tag="KR231_002986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HBH0005343.1"
                     /translation="MKKYISIILLVVLTMVVLVGCSPGKDNPKNKELSVVKQVKVAVP
                     DGLPAVAIAKLANENPEIKEGYETVYSIEKTPEAISTRVMKKDADIAIVPSNMAAIAY
                     NKTSSYNIVGTVGMGSLYLVSTENIKDYSDLVGKEVGCTGKGLTPDITIKSLLLQKDI
                     NYSDIKFNYVNSASELVPLLATGKVKTGIVPEPALSALMSKNPDIKIIKSLNDSWKEV
                     SGSKDGYPQSTLIVKSEFLRDNKDFVDSFVGQLSNSIDWANKNPEELGAYSEKIKIST
                     ESKIIGKSLERANLKYIPVKDMIKDYKNYYEKLANFDDKTLGGKVPDEAIYFVEK"
     gene            6889..7674
                     /locus_tag="KR231_002987"
     CDS             6889..7674
                     /locus_tag="KR231_002987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HBH0005344.1"
                     /translation="MKQYTLLRNKKNKEQFIDKMEVTLSCVILLFLWQIIALKIDNDI
                     FLPTVGQVFNSIKEIMLNSSFYIDILYSMGRCFFSFLLAMIFAIILSIVSYLNRFFRN
                     LLKPINALTRSIPTMILVVLALIWFEKDSTPFIVGFTIVFPILYDNVLGAILNIDKNL
                     LEMANVYKIRFIDKVLKIYLPAIKFQIISILVSTFSLSLKVAIAGEVYSQPTYGIGTM
                     IQTEKINFNTSGIFAWIIIVLLISAILQIAQKFLARRAFLWKR"
     gene            7662..8360
                     /locus_tag="KR231_002988"
     CDS             7662..8360
                     /locus_tag="KR231_002988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH0005345.1"
                     /translation="MEKIKLSIENINKRYDSRIIFRDFNIDFYVNEVNCILGKSGCGK
                     TTLLNIISGIIKNDTNNLNIKENLNRVGNKLEASYIFQDDRLIDWLTVEENIKIVVNK
                     YYNKTQLNKICDEYLELVGISDYKKFYPQMLSGGIRQRVNIARAFIYPSKNIIMDEPF
                     KSIDAKNTQLIMDNFRNILRKEKRTVLFVTHNIEEALFLADRIFILGDSPIRIKKILK
                     NSKELEKNEVLKLI"
     gene            8483..8956
                     /gene="ybaK"
                     /locus_tag="KR231_002989"
     CDS             8483..8956
                     /gene="ybaK"
                     /locus_tag="KR231_002989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cys-tRNA(Pro) deacylase"
                     /protein_id="HBH0005346.1"
                     /translation="MVKTNAMRILDSNKIDYKVMSYEVKSEHVDGVEVAHDIGRDVNE
                     VYKTLVTQGVSKNIYVYVIPVHENLDLKKAAKVAKEKSVEMIHVKDINKLTGYIRGGC
                     SPIGMKKLYKTFVNESAKNLDTIIVSAGKIGYQIELSPFDLQRLIKVEFVDVIKK"
     gene            9153..9992
                     /locus_tag="KR231_002990"
     CDS             9153..9992
                     /locus_tag="KR231_002990"
                     /EC_number="4.2.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fumarate hydratase"
                     /protein_id="HBH0005347.1"
                     /translation="MRKIKSEQIVEQVKKLCIEASLYLGEDVLSCIKEKAKSEKSEVG
                     KNILNILVENAEIAKEKNIPICQDTGMAVFFVEIGQEVLIEGDTLTDAINEGVRQGYE
                     EGYLRKSVVSPINRVNTKDNTPAVIHYDMVKGDKIKIEFAAKGFGSENMSKMKMLKPS
                     DGLEGIKKFIIDTVSEAGPNPCPPMVIGVGIGGTVDKCAQIAKKALFRELGEFNKDEN
                     IAKLESELLTAINKLGIGPQGLGGTTTALGLNIETFPTHIAGLPVVVNINCHASRHKK
                     VVI"
     gene            10005..10553
                     /locus_tag="KR231_002991"
     CDS             10005..10553
                     /locus_tag="KR231_002991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S-containing hydro-lyase"
                     /protein_id="HBH0005348.1"
                     /translation="MIKITTPVNEIDIAKLNCGDTISLSGILYTARDAAHKRLIDCIN
                     KGEELPFDVYGQGIYYVGPTPTKPGEVIGAAGPTTSYRMDDLTIPLLERGLRLMIGKG
                     KRSDEVIEGMQKYGAVYLAAIGGAGAYISNSIKSCEIIAYEDLGAEAIRKIVVEDLKL
                     TVAIDSYGNNIYEQGRAIYECK"
     gene            10619..11800
                     /locus_tag="KR231_002992"
     CDS             10619..11800
                     /locus_tag="KR231_002992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent malic enzyme"
                     /protein_id="HBH0005349.1"
                     /translation="MSKDYAKLALEMHEINKGKVSVESKVEVKTKDDLSTAYTPGVAE
                     PCLKIHENQDDVYRYTSKGNLVAVVSDGSAVLGLGNIGAEASIPVMEGKAILFKQFAD
                     VDAFPICLKTNDVDEIVKSVELMEPVFGGINLEDISSPRCFEIEERLKKSLSIPVFHD
                     DQHGTAIIVAAAIINSIKLIENKKIEDLEIVINGAGAAGIAIAKILLNMNVKNIILCD
                     RSGALEASIENLNYVQKEMLKVTNIRNEKGPLKDIIKGKDVFIGVSGPGAVTKEMVES
                     MSEKPIILAMANPAPEIMPEEAKLGGAFIMGTGRSDFPNQVNNVLAFPGIFRGALDVK
                     AKEINEEMKIAAAYAIANTISDEEICPEYILPDVFNKNVVKNVAKAVKEAAIKTKVNR
                     I"
     gene            11968..12354
                     /locus_tag="KR231_002993"
     CDS             11968..12354
                     /locus_tag="KR231_002993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009248914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBH0005350.1"
                     /translation="MEYKVNDQELNASMFIPFVNRIWPGDYDTDKTQTALSKTLNITA
                     YDDKVLVGCLRVLSDGYYFGTITELLVLPEYQKQGIGSKLFQLAKENTPTMLYFGAQP
                     GVEEFYEKNGCQRSLQSYIIKKKDSY"
     gene            12504..12767
                     /locus_tag="KR231_002994"
     CDS             12504..12767
                     /locus_tag="KR231_002994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ribbon domain-containing protein"
                     /protein_id="HBH0005351.1"
                     /translation="MEETKFCQCCAMPMGQTDELYGTNKDGSKSTDYCSYCFKDGEFT
                     ADISMEEMIEVCIPHMLQSNKDMTEDEARTMMNNFFPTLKRWK"
     gene            13293..13976
                     /locus_tag="KR231_002995"
     CDS             13293..13976
                     /locus_tag="KR231_002995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBH0005352.1"
                     /translation="MSSILLVEDDLSLIYGLEFSIQKSGFSIDIARTVKEAMQMYEEK
                     NYDLLLLDVSLPDGNGFQICEKVREVSNIPIIFLTASDEEVNVVMGLDMGGDDYITKP
                     FKLNELISRIKALLRRYNVASNVNELSSNNITIKLLENRVFKGKFEVELTTAEYKLLC
                     LFMKNKNIVLTRKNILDKLWDGNGSFIDDNTLSVYVRRLRNKIEDNPENPKFLLTVRR
                     MGYKWNVIK"
     gene            13987..15228
                     /locus_tag="KR231_002996"
     CDS             13987..15228
                     /locus_tag="KR231_002996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBH0005353.1"
                     /translation="MKIFSNKDIKIFFLMLISILVMFIIVGQIVVISITNNYKKTLIE
                     HDYNIAGYLYSIGVDKSKIPSAFVAHEDKYILKGKEILDTAGYGFDIDVSFTPSVKLF
                     QSKYIKTMSIYLLVFFTMIIFILYMYFFRQQSKIEEASYKIDLFMNGNINERLNTYEE
                     GSLSKLFSSIDVMSTSLNTHILKEKQSREFLKNTISDISHQLKTPLTALIMYNQILQE
                     ESHNSDVVEAFVQKSQSELERIETLIKNLLKITKIDSKTIILNKNNVNLKNLIVKILY
                     SFETRAEKEGKVISVNGSENTLLFCDYEWMSEALSNLIKNALDNTKENDKITIEWFET
                     TITTIVSVKDTGNGIHVEDIHHIFKRFYRSKFSKDNQGLGLGLPLVKSIVEQHNGTIS
                     VESKLSQGSIFTISFLKLTNM"
     gene            15300..15983
                     /locus_tag="KR231_002997"
     CDS             15300..15983
                     /locus_tag="KR231_002997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002574824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH0005354.1"
                     /translation="MDILVVNNLCKTYGNGYTKVEALKDVSFTVSKGEFVTVVGESGS
                     GKSTLLNLLGGLDTPTSGRIFIDGKEICSMKEEKQTIFRRRNIGFIFQAYNLIPELTV
                     EQNIIFPLLLDYKKPDTIYLDEVLTILGLKDRKNHLPNQLSGGQQQRVAIGRALITKP
                     SIILADEPTGNLDSKNSNDVISLLKVTAEKYNQTIIMITHNTNIASTADRILQVSDGV
                     LTDLGVNRE"
     gene            15980..18310
                     /locus_tag="KR231_002998"
     CDS             15980..18310
                     /locus_tag="KR231_002998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBH0005355.1"
                     /translation="MRSYLELVPQYAKVHKKKNRTTILCIIIAVCLVTAIFGLADMAI
                     QCQKIQFIKDDGNWHIVIRNIDEKFISEINSRVDIAHHGRGQVVDNGEFKSKEILIQG
                     LDEEVAKQFNLEIIRGRYPIGENETLIDEDAVKSFNLKIGDFIKIKLADGRNKNYKIV
                     GEYSSISSLRATDKHGLILSILGTQAIKKSETYDYYYITFKEKVNIRKATSDIKNTFN
                     LSDKQIGKNERLLSIIGQGDSDFSKPLYLTAGLLFVLVLVASIIMIYNSFNMSVIERV
                     KFFGLLRCLGSSKHQVKKFVVLESLILSIKAIPIGLVLGSLVTIISSIFLKYVNELFS
                     SMPILKVSFIGIAFGIIVGFLTVILSAIIPAKKASRVSPLSAVRGNLMSKEILNNGKT
                     SKVANIGSFKIETSMGLNHAFSRKKSFVLMTSSFAISIILFLGFSVLIDLMYQGLKPM
                     KPEAPHISIVDPNFKSVLTKEDINEISNIKGVKKVYSRMMTDIEATYNGKKTKSQLIS
                     YEKYQFNWAKKYLLKGEVNENKLQSENLALVEEGHGFDIGDKIYIKNGNAEKELEVGG
                     ILSSIPFEAKDKYIGNIITSENTFTNITGIKGYIIMDIQVDKDTPGDLIENIRRVVDD
                     NLEVRDKRQSNLEVKNSFYTMATFVYGFVFIIAIISMFNIINSMNISVTSRKNYYGVM
                     RAVGISNRQLRRMVIVEAGSYAVSGCLLGSILGLILHRYMFISLVSSMFHLEWQVPFN
                     LLLITVLTMIIITLLSVRKPIKKICELDIIDSINAQ"
BASE COUNT         7306 a         1881 c         3306 g         5828 t
ORIGIN      
        1 caaataaatc ttaagctatc ttatttaatt ctaatacagg aagaaggtaa atgtatattg
       61 aaaaaatcat agaaatagaa gtaaacaatt taaataaata caaaggtttg caaaagaagt
      121 aatataatta tatacaatga ggatgtgagt atgatgaaca gactaaagcc aagaatttta
      181 ggtattagta tcttgtttat tattataatt attttaacat gtggagctgt tttcaagttt
      241 aaatttaaat tagataataa attaaaagaa accacacata catatttgtc tgagtttaca
      301 gaacacaata taattaatct caagacaaga cttagtggtc aatttgacat gcttgaatct
      361 attgctaact tcataggaaa cttgaataat ataaatgatg aaatggtgat tgatttaatg
      421 gattctgatg taaagcgaag ttctttaatt agaatgacta tctctacatt agatggggaa
      481 tgttattcta atgatggaat tacccataat gttcaagata gagattattt taaaaaagct
      541 aaaaatggag aaaagaatat atcagagcct ttaaaatcta ttgttaataa taaagaaata
      601 atagttttat ctaccccagt ttataaaagt gggaaaatag ttggtgtttt aagtggaatt
      661 tatgattcaa aaaagttaaa tgaattatta ggattatctg catttgatga aaaagcagat
      721 gtttttgttg caaagaaaaa tggagatata attgctcaaa aaacaaataa aaatagtaag
      781 acgatatcat gtatatttca gctttttgac aaagataatt gtgatgaagt tgattgtcta
      841 aaaactataa aagaaaatat gaaaaatgat aagtctgagt attttaatta taacttagat
      901 aatgaaaaat ttatgttaaa ctatcagcca cttggagtta atgattggta tgttttttct
      961 gttgtgccaa ataaaatagt gtctattcag tcagagaata tatcttatga tgtatatatt
     1021 tttgcatgaa atactactag ttatattaat ttttataata tatatagcat gtattataaa
     1081 taataacacc aaaattatta taaatgaaaa agaaaaattt aaagtactca ctgataatat
     1141 actaggaggg gttaaaacct gtttaaaaga tgaatatatg actatgacat atgtaagtca
     1201 ggggttttta gagcttacag gttactcttg tgaagattta aataaaatat ttaaaaatag
     1261 atttaaagac atgatttata aagatgattt agacaagttt aattgtatta ttctaaacca
     1321 attagaaaaa caagataaaa ttgaagttga atatagaatt gtaagaaaag atggaagtat
     1381 aatttggatt ttggagagaa gtaagtctat aaatgataat aaaggaagtg agtgtattca
     1441 gggagtttta actgatataa cagaatttaa gaaaatacaa gaagagttag attcaaaaag
     1501 atttgaaata caggctatca atgatagtat tgttggtgga atagtgataa ctgagataaa
     1561 tgatgatttt gatagtatat atttaaatga aggttattta aatatgattg gatatacacg
     1621 caaacaactg aaagatgagc taaataataa attaatcaaa cttattttta aagatgatag
     1681 aacagaatta attaatagta taaacaaaca actcaaatta agtgatacat ttgcatctga
     1741 acaaagagtt gaaaaaaggg atggcactat tatatggatt ttattaaaag gaagaaagat
     1801 gatttatgat aatggaaaat ctgtactttg ttgtgttatt gtagatatta cttctgctaa
     1861 attattagag caagaactta aaaagagtga agaacgtcat gaaatcattc taaagcagac
     1921 gcaaaatatt ataatagaat gggatataga aaaagataaa atgaatatat cacctaattg
     1981 gtataataag tttaaatatg accctataac tgaaaacgca acaaaaaata taattaaatc
     2041 agtagatata tatcatgatg atatggataa gtttatttca ttaattaaac ttacttcaca
     2101 aggtagtgag tatgaagagt gtgaaattag acttagaact agagatacta tttacgcttg
     2161 gtttagtata aaggcaacaa ctttatttga taataatggt aaaccttata aagtagtagg
     2221 aagtttgact gatattgatg aatcaaaacg agaagctgaa aagttgaaag aaagggcaga
     2281 aaaagaccct cttacagatt tgtataataa aaaagcatca caatcactta tagaagagta
     2341 cataacattg gataaaaaaa gaaaaggtgc tttaatgatt attgatattg atgactttaa
     2401 aggaataaat gataatttag gacatttata tggggatgct gtattaagtg aagttgcaaa
     2461 tgacctaata aatctattta gagcaaccga tatagtaggc agaattggtg gagatgagtt
     2521 tattgtattt ataaaagata tttctaaaac aagagatatt ataaataaag cagaagaatt
     2581 ggtaaaaaca tttgaaaggt cttttttagg taaaggacga aattataaaa tatcattaag
     2641 tgtaggaatt gctaagtttc cacaagatgg tatggactat atgacactat ttagaaatgc
     2701 ggatatagct ctttactcag ccaaagggaa gggcaagaat tgttatacat tgtatgataa
     2761 aaaaattgat aaagtccaat atataactaa tacaagaaat gcaggagata gtgataatgt
     2821 agagatgtct tttaaagaac atatcacaaa ttatatattt gatatactat atgaatcaag
     2881 tgatatagaa gtggcagtaa atttaattct aagtattgta ggtaaacact ttaatgtgag
     2941 tcgcatgtat atatttgaaa attcagatga taatcgagta tgtaaaaata catttgaatg
     3001 gtgtaacgaa ggtataacct cggaaattaa taatcttaaa aatatttgtt acaaggattt
     3061 aggcaactat cttttaaatt ttaatgcaga tgggttattt tattgtaatg atattgaaaa
     3121 tttaggtagt gatgtgaaaa aagtacttaa gccacaaggc atacgttcaa tattacaatg
     3181 taaaatttta gagggtaatg aatttagagg gttcatagga tttgatgaat gttcatataa
     3241 tcgtatgtgg actaatgatg aagtgaacac tttgacattt atatctaaaa cgctcaatat
     3301 gtttttatta aaaatgcgta ttcagagtaa gctagaagag tctttaacaa ttcaaaaatc
     3361 tgtgatggat aatatggata tatgggcata tgttgttgac aggaatacct atgaattact
     3421 atttatcaat aaaaaaatgc ttgagtcagc accaaacact catgtaggtg atttatgtta
     3481 taaagcgata tggaataatc aagataaacc ttgtaaaaaa tgccctatga tatatttaaa
     3541 agatggtgat gatacttata aatcattcat gcataataaa aagtttgagg tacaggcaaa
     3601 tataactaca actactttga aatggtttga tggtaaagat gcatgtttaa tatttggaag
     3661 tgaaataact agtattgaag ctgaagaaaa tacttaaaat actgtgttat atatatactt
     3721 aaaatcgcaa tttgaattta ttagacttaa aatgtctata taaatcattt aagttgtggt
     3781 tttaagtatt ttttatgata taattaagcg ttaagaacaa aattaaaaga tacttttgta
     3841 taaaaaaata tttgttaaat atatattgag caggtgataa tatggaaaat aagtttttac
     3901 caataagcaa acaagatatg atagatagag gatgggaaga attagatttt gttctagtta
     3961 caggagatgc ttatgtggac catcatagtt ttggaacagc aataatatct agagttttag
     4021 aaagtgctgg gtataaagtt ggaataatag ctcaaccaga ctggagaact acagatgatt
     4081 ttatgaagct aggaaaacct agacttgcat ttctagttaa tgcaggaaat atggattcaa
     4141 tggtcaatca ttattctgta agtaaaaagc atagagaaaa ggatatgtat tctccaggtg
     4201 ggaaaatggg ttatagacca gatagagcta ctatagtata ttgcaataaa ataagagaag
     4261 catacagtga tgttgcaata gtaataggtg gaattgaagc gagcttaaga agatttgcac
     4321 actatgatta ttggagtgat aaggttagaa agtctatgtt aatagatagt ggagcagatt
     4381 tattagttta tggtatgagt gaaaagcaga ttgtagaagt agccaatgca cttaatgatg
     4441 gatatgaccc aaaatacatt agacatattg atgggacatg ctatatttca gatacattgg
     4501 aagaaatata tgataaatat atattaattc catcatataa agaaatttgt gaagataaaa
     4561 tgaagtatgt agaagctttt aaaattcaat atgatgagca agacccattt agaggtaata
     4621 taattgttca acctcatgga agtaagtatc tggttcaaaa taagccagaa aaaccactta
     4681 gtagagaaga actagatgaa gtatatggat taccatatca gaagacatac catcctgtgt
     4741 atgaaaaatt tggaggaata ccagctatag aagaagtaaa atttagtata gtaagttcaa
     4801 gaggctgttt tggtagttgt tcattttgtg caataacatt tcatcaaggt agagcagtgc
     4861 aaagtagaag tgaaaaatca attattgatg aagcaatagg aataacaaat ttagatgatt
     4921 ttaaagggta tatacatgat gttggaggtc caacagctaa ttttagaaga ccagcatgta
     4981 aaaaacaaat tactaaaggt gcttgtaaaa atagacaatg cttatctcca tcaccatgta
     5041 aaaatttaga tgcagaccac agtgaatact tacatttact tagagctgta agaaaattac
     5101 ctaaaataaa aaaggtgttt gtgcgttctg gaattagata cgattatgta atggcagata
     5161 agaacaataa atttcttaga gagttgatag agcatcatgt aagtggtcag ttaaaggtag
     5221 ccccagaaca tatatcagaa gaagttttaa agtatatgca aaaaccagca ggaaaaactt
     5281 atgataaatt tagacagaaa ttttttgcta taaatgaaga attaggtaaa aagcagtatt
     5341 tgatacccta tttaatgtct agtcaccctg gttctacctt aaatagcgct atagagttag
     5401 cagagtattt aagagatact cactaccaac cagagcaggt tcaggatttt tatccaactc
     5461 cagggactct atctacaacc atgttttata caggtattga cccgcttaca atgaagccag
     5521 tttatgttcc taaatcaaaa cgtgacaagg caatgcaaag ggctttatta caatatagag
     5581 cacctagaaa ttatgatttg gtatactctg cgttagttga agcaggaaga gaagacttaa
     5641 ttggttttgg acatagatgt cttataaagc caaaaaatga aaagccttat tttaatagaa
     5701 ataattctaa aaaaaatgta tctaaaggaa caaataaaaa caaaaaaact aatacaaata
     5761 acagaagtaa taaaaatcaa caaaaaagtt caactaaaaa aaagaaaaaa cattaaagta
     5821 taaataaaaa tacttaaaaa agaaggatta ttcgataaat taacagaaat tagtataaat
     5881 aaatataatt attttaatga cgttaccttt gggaggaaga gatgaaaaag tatatttcta
     5941 taatattatt agtggtgttg actatggttg ttttggtagg atgttcacca ggaaaagata
     6001 accctaaaaa taaggagcta tcagttgtca aacaagtaaa agtagctgtt ccagatggac
     6061 taccagcagt ggcaatagct aaacttgcaa atgaaaatcc agagattaaa gaaggatatg
     6121 aaacagtgta tagcattgaa aagacacctg aagcgatttc cactagagtg atgaaaaaag
     6181 atgcagatat agctatagtt ccttcaaaca tggctgcaat agcgtataat aaaacttcat
     6241 catataatat tgttggaact gtaggaatgg gttcacttta tttggtgtca acagaaaata
     6301 taaaagatta ctctgattta gttggtaaag aagttggatg tactggaaaa ggacttactc
     6361 cagacataac tataaaaagt cttttgttac aaaaggatat aaattattca gatataaaat
     6421 ttaattatgt aaattcagca agtgaactgg taccattatt ggctactggt aaagttaaaa
     6481 caggtattgt tccagaacct gcacttagtg ctttgatgtc taaaaatcca gacataaaaa
     6541 ttataaaaag tttaaatgac tcatggaagg aagtaagtgg ttcaaaagat ggttatcctc
     6601 aatctacttt aattgtaaag tctgaatttt taagagataa taaagatttt gttgattctt
     6661 ttgtaggtca attatcaaat agtatagatt gggcaaacaa aaatcctgaa gaattaggtg
     6721 catattctga aaaaataaaa atatctactg aatcaaagat aataggaaaa tctcttgaaa
     6781 gagctaattt gaaatatatt ccagttaagg acatgattaa agattataaa aattactatg
     6841 agaaattagc taattttgat gataagacat taggaggcaa agtaccagat gaagcaatat
     6901 actttgttga gaaataaaaa aaataaagaa caatttatag ataaaatgga ggtaacactt
     6961 tcttgtgtta tcctcttatt tttatggcaa attattgctt taaaaattga taatgatatt
     7021 tttttaccaa cagtaggtca agtgtttaat agtataaaag agattatgct aaattctagt
     7081 ttctatatag atatacttta ctctatgggg agatgttttt ttagtttttt actggctatg
     7141 atttttgcta ttatactttc aatagtgtct tatttaaata gattttttag aaacttatta
     7201 aagccaatca atgctttgac acgttcaata ccaactatga tattggtagt acttgcactt
     7261 atttggtttg aaaaggatag tacccctttt atagttggat ttactatagt ttttcctata
     7321 ttgtatgata acgttttggg cgctatattg aatatagaca agaacttatt agaaatggct
     7381 aatgtgtata aaataaggtt tatagataag gtgttaaaaa tttatttacc agccataaaa
     7441 tttcaaatta tatctatact agtatcaaca ttctctttaa gtttgaaagt tgctatagca
     7501 ggagaggtat atagtcaacc tacatatggt attggaacta tgatacagac tgaaaaaatt
     7561 aactttaaca catctggaat atttgcatgg ataattattg ttcttttaat atctgctatt
     7621 ttacaaatag ctcaaaagtt tttagcaagg agagcttttt tatggaaaag ataaagttga
     7681 gtattgaaaa tataaataaa agatatgata gtcgtattat atttagagat tttaatattg
     7741 atttttatgt aaatgaggta aattgtatcc ttggaaaatc tggttgtgga aaaactacac
     7801 tcttgaacat aataagtggg attattaaaa atgacaccaa caatctaaat atcaaagaaa
     7861 atttaaatag agtaggaaat aagcttgaag ctagttacat atttcaagat gatagactta
     7921 tagactggtt aacagtagaa gaaaatataa agatagttgt aaataaatac tataataaaa
     7981 ctcaattaaa taaaatttgt gatgaatact tggaattggt tggaattagt gattataaaa
     8041 aattctatcc tcaaatgctt agtggaggta ttagacaaag agtaaatatt gctagagctt
     8101 ttatatatcc atcaaaaaac attataatgg atgaaccttt taaatctatt gatgcaaaga
     8161 atacacagct tataatggat aatttcagaa atatattaag aaaagaaaag agaactgtgt
     8221 tatttgtaac tcataatatt gaggaagcat tgtttttagc agataggata tttattttag
     8281 gagactctcc aattagaata aaaaaaatat taaaaaattc taaggaattg gaaaaaaatg
     8341 aagttttgaa gttgatatag agttataata atactgtcgt tttaaaatat atttggttaa
     8401 aatctataag actatattaa aatagtacag aatattcaaa actgtgtata atgttcgtat
     8461 tttataaaaa ggaagtgaat gtatggttaa gactaatgct atgagaatat tagattcaaa
     8521 taagattgat tataaagtaa tgtcttatga agtgaaaagt gaacatgtgg atggtgttga
     8581 ggtggcacat gatataggaa gagatgtaaa tgaagtgtat aagacattag taactcaagg
     8641 agttagtaag aatatatatg tatatgtaat accagtacat gaaaacttag acttaaaaaa
     8701 ggctgcaaaa gtagctaaag agaaaagtgt agagatgatt catgtaaaag atataaataa
     8761 gcttacaggt tatattagag gcggatgttc tcctataggt atgaaaaagc tttataaaac
     8821 ttttgtaaat gaaagtgcaa agaatttaga tacaattatt gtgagtgcag gaaaaatagg
     8881 atatcaaata gaactatctc catttgattt acaaagactt ataaaagtag aatttgtaga
     8941 tgtaataaaa aaataagaat tacatataaa atatagagct tatattctca ataataggtg
     9001 ttgtaatatt aataaaatga ataataattt taaaataaat attcagttac ttatgtgtaa
     9061 ttggtataaa aatattgaga aattttaaaa acaatggtaa agtgtaagta taatcacgaa
     9121 tattttttat aaagtaatgg agggatgttc gcttgagaaa aataaaatct gaacaaatcg
     9181 tcgagcaggt aaaaaaactt tgtatagaag cgagcctata tttaggagaa gatgttttaa
     9241 gttgtataaa agaaaaagcg aaaagcgaaa agagtgaagt tggaaaaaat atattgaata
     9301 tattagttga aaatgctgaa atagctaaag aaaaaaatat accaatatgc caagatactg
     9361 gtatggctgt attttttgtt gaaataggac aagaagtttt aattgaagga gacacactta
     9421 ctgatgctat aaatgaggga gtaagacaag ggtatgaaga aggctactta agaaaatctg
     9481 ttgtaagtcc aattaacaga gtaaatacaa aagataatac acctgctgtt attcattatg
     9541 atatggtaaa aggtgataaa attaaaatag aatttgcagc taagggattt ggaagcgaaa
     9601 atatgagtaa gatgaaaatg ttaaagccat cagatggatt ggaaggaatt aaaaaattca
     9661 taatagatac agtttcagaa gctggaccta acccatgccc tcctatggta attggagttg
     9721 gtataggtgg gactgtggac aaatgtgctc aaatagctaa aaaggcactt tttagagaac
     9781 taggtgaatt taataaggac gaaaatatag caaaacttga aagtgaacta ttaacagcta
     9841 ttaataaact tggtatagga cctcaaggct taggtggtac tacaacagct ttgggattaa
     9901 acatagagac ttttcctaca cacatagcag gtctacctgt tgttgtaaat ataaactgcc
     9961 atgcatcaag acataagaag gtagtaattt aggaggaaaa taaaatgata aaaataacta
    10021 cacctgtaaa tgaaattgat atagcaaaat taaattgtgg agatacaatt agtttgagtg
    10081 gtatacttta tacagcaaga gatgctgctc ataaaagatt gatagattgt ataaataaag
    10141 gtgaagaatt accatttgac gtatatggtc aaggaatata ttatgtagga cctactccta
    10201 caaagccagg agaagttata ggtgctgcag gtccaacgac gagttataga atggatgatt
    10261 tgactatacc tcttttagaa agaggtctta gattgatgat aggcaaggga aaaagaagtg
    10321 atgaagttat agaaggtatg caaaaatacg gagcagttta tcttgctgca ataggaggag
    10381 ctggagcgta tatttcaaat tcaataaaat catgtgaaat tattgcatat gaagatttag
    10441 gagctgaagc tataagaaag attgtagtag aagaccttaa gcttacagta gcaatagata
    10501 gctatgggaa taatatatat gagcaaggtc gagcaattta tgaatgtaaa taatgtttag
    10561 aaataaatat gaatatcaaa attaaaaata gttgtgtata ttttaaggag gaaaattgat
    10621 gtctaaggat tatgcaaaat tggcattaga aatgcatgaa atcaacaaag ggaaagtaag
    10681 tgtagaaagc aaggtagaag ttaaaactaa ggatgattta tcaacagcat atacaccagg
    10741 ggttgcagaa ccttgtttaa aaatacatga aaatcaagat gatgtttata gatacacttc
    10801 taaagggaat ctagtagcag tagttagtga tggaagtgct gtacttggat taggtaacat
    10861 tggtgctgaa gcatctatac ctgttatgga aggtaaagct atattgttta aacaatttgc
    10921 agatgtagac gcttttccaa tatgtttaaa gactaatgat gtagatgaga tagttaaatc
    10981 tgtagagttg atggaacctg tatttggagg tataaatttg gaagacatat cttctccaag
    11041 atgttttgag atagaagaga gattaaaaaa atctttaagt atacctgttt ttcatgatga
    11101 ccaacatggg acagcaataa tagttgcagc agccataata aactcaataa agttaattga
    11161 aaataaaaaa atagaagatt tagaaatagt tataaacgga gcaggagctg ctggtatagc
    11221 catagcaaag atactactta atatgaatgt taaaaatata atcttatgtg atagaagtgg
    11281 agcattggaa gctagtatag aaaatctaaa ctatgttcaa aaagaaatgt taaaagtaac
    11341 aaatataaga aatgaaaaag gacctttaaa agatattata aaaggaaaag atgtatttat
    11401 tggtgtttca ggtccaggag ctgttacaaa ggaaatggtt gaaagtatgt ctgagaagcc
    11461 aataatattg gcaatggcaa atcctgctcc agagataatg ccagaagaag caaaattagg
    11521 tggagcattt ataatgggaa caggtcgttc agacttccct aatcaagtca ataatgtatt
    11581 ggcttttcct ggaatattta gaggagcatt agatgttaag gctaaagaga taaatgaaga
    11641 aatgaagata gctgctgcat atgcaattgc taatacaata agtgatgagg aaatatgccc
    11701 agagtatata ttaccagatg tatttaataa gaatgtagta aaaaatgttg ctaaggcagt
    11761 taaagaagca gctataaaaa ctaaagtaaa tagaatataa atttttatat gctcatatat
    11821 tcttactttt atatacatat ctttatgatt aaacgtgtta gaaaacgtag taaatttata
    11881 ctatcagact ttacctttat tacttaaaat gatataatat gaatattata aattaataaa
    11941 tttaaattta ttgaggtgca agagataatg gaatataaag ttaatgacca agaacttaat
    12001 gcttcaatgt ttatcccatt cgttaacagg atatggccag gagattatga tacggataaa
    12061 acacagactg cattatcaaa aactttgaat ataactgctt atgatgataa agtgcttgta
    12121 ggatgtctgc gagttctttc agatggttat tattttggaa caattacaga attgcttgtt
    12181 cttccagagt atcagaaaca aggcattggt agtaagcttt tccagcttgc taaagagaat
    12241 acaccaacta tgctatattt tggtgcacag ccaggagtag aagagttcta tgaaaaaaat
    12301 ggatgccaaa gaagtcttca atcttacata ataaaaaaga aagatagtta ttaaagttcc
    12361 agctttcaat aatcttaaaa gtacaatatt ttagtggaat catttcattt tttattacta
    12421 atatgacata aacatgtcat attagtattg atatactttt aatatggtta agagccaaag
    12481 aaaaatataa ggagtgattt aaaatggaag aaactaaatt ttgccaatgc tgtgcaatgc
    12541 caatgggaca aactgatgaa ttatatggga caaataaaga tggaagtaaa agtactgatt
    12601 attgtagtta ttgttttaaa gatggtgagt ttacagctga tataagtatg gaagagatga
    12661 tagaagtttg tatccctcat atgcttcaaa gtaataagga tatgactgaa gatgaagcaa
    12721 gaacaatgat gaacaatttc tttccaacat taaaacgctg gaaataattt tatgcaaaat
    12781 tagttatatg caaaacatga aatatggtgt tgagaataag gggtggtgtg ctttatagca
    12841 taccacctgt tttgttactt gctagttcag gtattcttgt atgcttaaat atgttctcat
    12901 ctctctttct attttaaatt gtaaaaatct aaaatatgtt atttatattc tacttcttta
    12961 tccatgtctt tttctaccac aagtcaaatc caactacaaa atcatcattt tcaattcact
    13021 gtttaataga attaacagat aaagagttat aaaattttct attttttata taaaataata
    13081 caggtcaagc tgacttctag ctacttggga tagtgtatat atttatgata gttataggag
    13141 taataccaat cattagactg ttgatttgtg tagtcttttg taaaaacatt tgttttaata
    13201 tattgagttt ttgaaaaagt aaaattataa ttataataaa ttaagtgtaa taatgtatta
    13261 gaagtaaaaa taattaaaat agaggtgatt aaatgagtag tatattgtta gttgaagatg
    13321 atttaagctt gatatatgga ttagagttct ctatacaaaa aagtggattt agtatagaca
    13381 tagcaaggac agtaaaagaa gctatgcaaa tgtatgagga aaaaaattat gacttattgc
    13441 ttttagatgt atccctacct gatggtaatg gatttcagat ttgcgaaaaa gtacgagagg
    13501 tttctaatat acccattata tttttgactg cttcagatga agaggtaaat gtagtgatgg
    13561 gtcttgatat gggtggagac gattatataa caaaaccttt taaattaaat gaattaattt
    13621 caagaataaa agcattactt agacgttata atgttgcaag taatgtgaat gaattaagtt
    13681 caaataatat tactattaaa ttacttgaaa atcgtgtttt taaaggtaaa tttgaggtgg
    13741 aacttaccac agcagaatat aaattattgt gcttatttat gaaaaataaa aatattgtac
    13801 ttactagaaa aaacatattg gacaagttat gggatggaaa tggtagcttt atagatgaca
    13861 atacattatc agtatatgta agacgattga gaaataaaat tgaagataat cctgaaaatc
    13921 ctaagtttct attgaccgtt agaagaatgg gttataagtg gaatgtaatt aagtgagggt
    13981 attaatatga agatattttc taataaagat ataaaaatat tttttttaat gcttatatct
    14041 attttagtaa tgtttattat agtagggcaa atagtggtta taagtataac taacaattat
    14101 aaaaaaacgt tgatagagca tgattataat atagctggat acttatatag tataggtgtt
    14161 gataaatcta aaataccatc agcatttgtt gcacatgaag ataaatatat tttaaaagga
    14221 aaagaaatac tagatacagc tggatatgga tttgatatag atgttagctt tacaccaagt
    14281 gtaaaattgt ttcaaagtaa atatataaaa actatgtcta tctatttatt agtatttttt
    14341 actatgatta tttttatact atatatgtat ttttttaggc aacaaagtaa gatagaagag
    14401 gctagttata aaattgattt atttatgaat ggaaatataa atgaaagact aaatacatat
    14461 gaagaaggta gcttatcaaa attatttagt tcaatagatg ttatgtcgac atctttaaat
    14521 acacatatat taaaagaaaa acagagcaga gaatttctta aaaatacaat ttcggatata
    14581 tcgcatcaat taaaaactcc acttacagct ttaataatgt acaatcagat actacaagaa
    14641 gaaagtcata atagtgatgt cgttgaagct tttgtacaaa aaagtcaaag tgaactagaa
    14701 cgcattgaaa cattgattaa gaatttatta aagattacaa agatagattc aaaaacaata
    14761 attctcaata aaaataacgt taatcttaaa aatttaattg tcaaaatttt gtatagcttt
    14821 gaaactaggg cagaaaaaga aggaaaggtt atttctgtaa atggttcaga aaatacattg
    14881 ttgttctgcg attatgaatg gatgtcagag gctttaagta atcttataaa gaatgcatta
    14941 gataatacaa aagagaatga taaaataacg atagagtggt ttgagacgac tataaccacc
    15001 attgtttcag ttaaagatac tggaaatgga atccatgttg aggatattca tcatatattt
    15061 aaaaggtttt atagaagtaa gttttcaaaa gataatcaag gtttaggact gggattacca
    15121 ctagttaaat ctattgtgga acaacataat ggtactattt ctgtagaaag taaactatca
    15181 caaggaagta tattcaccat aagtttttta aagcttacta atatgtaaga taaaatacat
    15241 cttgcagtaa ggtatataga ttattattat attaatcaat tagaaaggtg agagagaaaa
    15301 tggatattct tgtggttaat aatttatgta aaacatatgg aaatggatat acaaaggtag
    15361 aggcattgaa agatgtatcc tttacagttt caaaaggaga gtttgtgact gtagttggag
    15421 aatctggttc aggaaagagt acactattaa atctcttagg aggtcttgat actccaacat
    15481 cagggagaat atttattgat ggtaaagaaa tatgttcaat gaaagaggaa aaacagacta
    15541 tttttagacg tcgtaacata gggtttatat ttcaggcata taaccttata ccagaactaa
    15601 ctgtggagca aaatataata ttcccattgt tattagatta taaaaaacca gatactattt
    15661 acttagatga agtattgact attttaggtc ttaaagatag gaaaaatcat cttccaaatc
    15721 aattatctgg tggtcaacaa cagagagttg caattggaag ggctttgatt acaaagccaa
    15781 gtattatact ggcagatgag ccaacgggaa atcttgacag taaaaatagt aatgatgtaa
    15841 tttcactttt aaaagtgact gcagaaaagt ataatcaaac cattattatg ataactcata
    15901 atacgaatat agcttctaca gcagatagaa tactacaggt ttctgatggt gtgcttacag
    15961 acctgggggt gaatagagaa tgagaagcta cttagaatta gtaccacaat atgcaaaagt
    16021 acataagaaa aaaaatagaa ctacaatttt atgtattatt attgcagtat gcttagttac
    16081 tgctatcttt ggacttgcag atatggctat acaatgtcaa aagatacaat ttattaaaga
    16141 tgatggaaat tggcacatag taattagaaa tattgatgaa aagtttatat cagaaataaa
    16201 tagtagagta gatatagctc accatggtag ggggcaagtc gttgacaatg gagagtttaa
    16261 atcaaaggag attttgatac aaggtttaga tgaagaagta gcaaagcaat ttaacttaga
    16321 aataataagg ggtcgttatc ctattgggga gaatgagact ttaatagatg aggatgcagt
    16381 taaaagcttt aatctaaaaa taggagattt tatcaaaata aaattagcag atggtagaaa
    16441 taaaaattat aagatagtag gtgaatattc atcaatatca agcttaagag ctacagataa
    16501 acatggatta atactttcaa tattgggtac acaagctatt aaaaaatcag aaacgtacga
    16561 ttattattat attacattta aagaaaaggt taatattaga aaagccactt ctgatattaa
    16621 aaataccttc aatttaagtg ataaacaaat tggtaaaaat gaaagattac tttctattat
    16681 aggtcaaggt gactctgact tttctaaacc attgtattta acagcaggat tactttttgt
    16741 acttgtttta gtagcaagta ttatcatgat atataatagt tttaacatga gtgtaattga
    16801 gagagttaaa ttttttggtc tgttacgttg tctagggtca tcaaaacatc aagttaaaaa
    16861 atttgttgtt ttagaaagtt taattttaag tataaaagct attccaatag gcttagtatt
    16921 aggaagtctt gtaactatta tatcttctat atttcttaag tatgttaatg agttattcag
    16981 ctcaatgcca attttaaaag ttagttttat tggtattgca tttggaataa ttgtagggtt
    17041 tttaactgta atattatcag ctattattcc agcaaaaaaa gcttcccgtg tatctccact
    17101 tagcgctgta cgtgggaatc taatgtccaa agaaatttta aataacggga agacaagtaa
    17161 agttgcaaat ataggaagtt ttaaaattga gacttctatg ggattaaatc atgctttttc
    17221 aagaaagaaa tcttttgtac ttatgacttc ttcatttgcc attagtatta tactattttt
    17281 aggttttagt gtgcttatag accttatgta tcaaggactt aagcctatga agccagaagc
    17341 tcctcatata tctattgttg accctaattt taagtctgtt ttaactaagg aagatattaa
    17401 tgaaataagc aatatcaaag gagtaaagaa agtatacagt agaatgatga cggatataga
    17461 agctacatat aatgggaaga agacaaaatc acaattaatt tcttatgaaa agtatcaatt
    17521 taattgggca aaaaaatatc tattaaaagg agaagttaat gaaaataaac tacagtcaga
    17581 aaaccttgca ttagtagaag aggggcatgg atttgatata ggagataaga tatatattaa
    17641 aaatggaaat gctgaaaaag agttagaggt aggaggtata ctttcctcaa ttccatttga
    17701 ggctaaagat aaatatattg gaaatattat aacatctgaa aatactttta cgaatataac
    17761 aggtataaag ggttatataa taatggatat tcaggttgat aaagatactc ctggagattt
    17821 aattgaaaat ataagacgtg tagtagatga taacttagag gtcagagata aaagacaaag
    17881 taacttagag gttaaaaatt cgttttatac tatggcaaca tttgtatatg gatttgtgtt
    17941 tattattgcg attataagca tgtttaatat cataaatagc atgaatataa gtgttacaag
    18001 tagaaagaat tactatggtg ttatgcgtgc agttggcata tccaacagac aattaagaag
    18061 aatggtaata gtagaggcag gttcatatgc agtgagtggt tgtttattag gtagtatact
    18121 aggattaata ttacataggt atatgtttat atcgttagta agctcaatgt ttcatttaga
    18181 gtggcaagta ccttttaatt tactacttat cactgtacta actatgataa taataacttt
    18241 attatcagta agaaaaccaa tcaaaaagat ttgtgaatta gatataatag actcaataaa
    18301 tgcacaataa atataggtat t
//
LOCUS       DAEPHU010000077        18072 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 01A10CD0081
            SAMN05941466-rid12468953.denovo.077, whole genome shotgun sequence.
ACCESSION   DAEPHU010000077 DAEPHU010000000
VERSION     DAEPHU010000077.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941466
            Sequence Read Archive: SRR6291087
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 18072)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18072)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068158.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 22:43:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,892
            CDSs (total)                      :: 3,805
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 87
            rRNAs                             :: 8, 1, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 55
            CDSs (without protein)            :: 55
            Pseudo Genes (ambiguous residues) :: 0 of 55
            Pseudo Genes (frameshifted)       :: 21 of 55
            Pseudo Genes (incomplete)         :: 28 of 55
            Pseudo Genes (internal stop)      :: 16 of 55
            Pseudo Genes (multiple problems)  :: 8 of 55
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18072
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941466-rid12468953.denovo.077"
                     /strain="01A10CD0081"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            <1..1131
                     /locus_tag="KR231_002999"
     CDS             <1..1131
                     /locus_tag="KR231_002999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0005356.1"
                     /translation="KTTIFYDLNNTYDVLLDTDTGVLFNLNVFAISQDNSKHILFSAI
                     ISIFAYPIYLFCTSIANPGTTDFNSAYGFGLICLQIITSAMSITLVFNHIKKIKMQRL
                     TLILLTMIMIFSFPQLFMTLNVERFIYSQFSLIFFIVIANKMKGKNSYLVELAAIPLF
                     GITISNIYLYFFNMIFEFKLKIGKMLKHLITFILMAYICVVSTKSYESFMNLGNVIQY
                     DTKFISGEPILEKIAMIIERLLYSVFYFPGASIKKGLFLQNGEVATIPVILTLLALCF
                     CVLSVIENSEKRVPKLCMGIIIFNLTLHGIVGYNLVNSSIMAINFSFAVIILLAYFTK
                     ALRKNEKNMYNIFLSLLLVTIVISNVNGFIEILNIGIKSYPV"
     gene            1160..2047
                     /locus_tag="KR231_003000"
     CDS             1160..2047
                     /locus_tag="KR231_003000"
                     /EC_number="2.4.2.45"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="decaprenyl-phosphate phosphoribosyltransferase"
                     /protein_id="HBH0005357.1"
                     /translation="MKQTNTSIRLLTKISDYIKLMRIKQYIKNFFVFSAIIFSNNILN
                     INLFLNTFIAFVCFCLMSSSVYALNDAIDMDKDKKHPKKCNRPVASGRISKKSANILF
                     VVLALISVCLSTVVSFNLSIILSLYLINNILYSLKLKNIILLDVFSISLGFILRVYAG
                     CVAISVSLSNWIILCTFFLSLYLALGKRKKEIETLRDDAVEHRKILEDYDIENLNQMM
                     IVILSSTIVCYALYSTSNPEKPHMIFTTIFVVYGVLRYNYIINTTNENNPTDIVLKDN
                     ALKINVILWIITCLIILIF"
     gene            2081..2710
                     /locus_tag="KR231_003001"
     CDS             2081..2710
                     /locus_tag="KR231_003001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IB family hydrolase"
                     /protein_id="HBH0005358.1"
                     /translation="MKKSVLLLDVDYTVINTDSMIDFFIYSLKNKTFKTIIKLPYIIF
                     ILFMYLIRIIPLKKAKEAIFYPIVDFSEEDLKKFFDDCIMKKINESMKKVIYKNKEED
                     NVIIMITASPYAYMKYFKYYGLADEVIGTEFFYENSRYKNKFIGENCKGIEKVKRIKA
                     VLGKLGIEIDYENSYAYSDSKSDLPMLSLTKNAFLVSKKDGEVIEQINS"
     gene            2715..3179
                     /locus_tag="KR231_003002"
     CDS             2715..3179
                     /locus_tag="KR231_003002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="small multi-drug export protein"
                     /protein_id="HBH0005359.1"
                     /translation="MSLRIGGNSLGYLHILILSMVPVTELRGAIPIGIAMGLNPIWVY
                     VFSVIGSTLVSIPLILTFRHVLQFLRGKKLFKGIADVIDRKINSRMKKLKSVSIIGII
                     LFVGIPLPTTGTWTASAIASILKMRIKDAFMGVFLGNLLSGVIVSALSLHII"
     gene            3429..4796
                     /locus_tag="KR231_003003"
     CDS             3429..4796
                     /locus_tag="KR231_003003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HBH0005360.1"
                     /translation="MENSNTNLGSESVGKLLFKLATPAIIAQIVNVLYNIVDRIFIGR
                     MENGEVAMAGVGVAFPIIIIITACSYLIGMGGGPLAAIKMGEQNNDEAEKIMSNSFSV
                     LVILAILLTIGFKIGKEPLLWMFGASESTIGYSMDYLNIYLIGTVFVQISMGMNTFIN
                     TQGFATTGMMTVAIGALINIILDPIFIFGFNMGVKGAALATIIAQGVSAIWVLMFLFG
                     KKSILKIKKKYMIPKASIILPVLGLGISPFIMQSTESLVLIALNSKLQMYGGDLAVGS
                     MAIMSSIMQILMLPNMGVTQGAQPIISYNYGSGQLDRVKKTFKLCLLSCFTYSTILWL
                     LLMIFPEFFVSIFNKNPQLLSMTSWSIKIYFAGAFMFGIQIACQQTFLALGKATISLV
                     LALLRKIVLLIPLIFILPTFFNEKLFAVILAEPVADITAATITAISFFIFYKCFLSKP
                     KAIKE"
     gene            4996..6270
                     /locus_tag="KR231_003004"
     CDS             4996..6270
                     /locus_tag="KR231_003004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418693.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S1 RNA-binding domain-containing protein"
                     /protein_id="HBH0005361.1"
                     /translation="MFIMENDLTMQELLDQQEQVFSKVKVGELTTGKITAVRNDEVQL
                     GLDYGFDGIIPISELNIEKNQYIEDIYHIGDEITAVITKVSQKDGTITLSKLQLDKRN
                     DFAELQKAYDEHRIITVNVEKNIDKGVFANYNTYTFFIPISQLDTKFITDTSKFVGLN
                     LEVYIKELDVRKNRLVASHRDVLQERINKEREERRAQIKAEKEAERARIKQEREEEKA
                     RIKAAKEDLFNSLEVGQKRDGKVTKIMPYGAFVDIGGIEGLAHINNLAWTRVESVEDV
                     VSEGQEVEVYVLDVNKETKKIALALKDINNDPWDLIAKEVQIDDVVNAKVLRIIEKGA
                     FVQIKEGVDAYLPISELSDTRVAKVTNVVNIGDEVKVKILDFKPKTKRMLVSIKEATR
                     EPEEDITEYLEVEESLGSIGELFKDKFKDLEV"
     gene            6388..7107
                     /locus_tag="KR231_003005"
     CDS             6388..7107
                     /locus_tag="KR231_003005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase"
                     /protein_id="HBH0005362.1"
                     /translation="MKKSIMDVHCHTLISGHAHSTFKENVEEASKKNIKYLGISDHGP
                     NMPGGPHPFYFYNLHLLPREVQGVKILRGIEGNIMDYNGNLDVQEDMLQHLDYIIASL
                     HRPCIASGTKEENTNAILKVMDKPKVKIIGHPDDSRYPLDYEPIVKKAKDKNILLEIN
                     NSSLSSNSHRTGTWENVSHMLTLCKTYGARVILGTDSHICYSIGEFENAEKVLEAVDF
                     PDELVINYHEDEIIEFFDINF"
     gene            7128..7574
                     /locus_tag="KR231_003006"
     CDS             7128..7574
                     /locus_tag="KR231_003006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0005363.1"
                     /translation="MSKNKFIYMNYYDNGYFKKGMTIYMVLALIILATIFIYSTTILY
                     ILCIITAVFLFKQGRDFSNKYEGKVYITLDNHSILINNQCIFSIKSKQSQKFNYKIIE
                     KIEVVKNILNIYTNESNYKIRLRALSLEDEKKLLNIIDEKMKKFKA"
     misc_binding    7722..7968
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            8092..9834
                     /gene="leuA"
                     /locus_tag="KR231_003007"
     CDS             8092..9834
                     /gene="leuA"
                     /locus_tag="KR231_003007"
                     /EC_number="2.3.3.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-isopropylmalate synthase"
                     /protein_id="HBH0005364.1"
                     /translation="MKCGKYKKYDKMQIVNRKWPDNEIFKAPIWCSVDLRDGNQSLPT
                     PMSVNEKVRMFKMLIDTGFKEIEVGFPSASNTEYTFLRKLIDENMIPDDVTIQVLTQS
                     RAHLIEKTFESIRGCKKAIIHLYNSTSVLQRDVVFNMSKQEIIDIAVEGAKLFNEEVK
                     KYPETEFTFEYSPESFTGTEMDYALEICEAVIDVWKPTPQKKVIINLPSTVEMATPNV
                     YADQIEWFCKNISCRDSIILSLHTHNDRGTCTAASELGLLAGADRLEGTLFGNGERTG
                     NMDIVNVGLNLYTQGIDPELDFSNIDKIIGIYEDCTKLMVHDRHPYAGNLVHCAFSGS
                     HQDAIRKGMIAMKNRDNDYWEVPYLPIDPHDIGREYKEIIRINSQSGKGGAVYIMETD
                     YGFMIPKNMHSDFGNVVKMESDRIGEELSSEAIFNLFKKEYIEVESPYKVKKYKIKSM
                     DELNYENDDSNDTNMIEMTARISYMGNEQRIVGIGNGPVDSFNNALKQCGMKDYKFRY
                     YWEHALEEGSHSRGVAYVGIEHNNEVYFGVSISENINTAAINALMNAINKSYIEEEIK
                     NGDDYDAENISQTC"
     gene            9791..11068
                     /gene="leuC"
                     /locus_tag="KR231_003008"
     CDS             9791..11068
                     /gene="leuC"
                     /locus_tag="KR231_003008"
                     /EC_number="4.2.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-isopropylmalate dehydratase large subunit"
                     /protein_id="HBH0005365.1"
                     /translation="MGMTMTQKILAKHAKLNEVKKGQLIEADLDVVLGNDITSPVAIR
                     EFEKLGIEDVYDKTKVVMVLDHFTPNKDIKSAEQCKFTRSFAKSKGVVNFFDVGDMGI
                     EHVLLPEKGIVTAGDVIIGADSHTCTYGALGAFSTGVGSTDMGAGMATGKCWFKVPGA
                     IKFVLKNKPNKWISGKDIILHIIGEIGVDGALYKSMEFCGDGVEYLSMDDRFTICNMA
                     IEAGAKNGIFPVDDKTMEYINSHKCSTMTKDVNIYEADEDAVYDEVYEIDLAELKETV
                     AFPHLPENTRTVDEIDKDIKIDQVVIGSCTNGRISDLEVVAEIMKGKKVADGVRVMIF
                     PGTQKVYLEAIEKGYITTFIEAGAAVSTPTCGPCLGGHMGILAAGEKSISTTNRNFVG
                     RMGHVDSEVYLASPAVAAASAITGKISKPSEII"
     gene            11083..11574
                     /gene="leuD"
                     /locus_tag="KR231_003009"
     CDS             11083..11574
                     /gene="leuD"
                     /locus_tag="KR231_003009"
                     /EC_number="4.2.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-isopropylmalate dehydratase small subunit"
                     /protein_id="HBH0005366.1"
                     /translation="MIANGSVFKFGDNIDTDVIIPARYLNIADYKELATHCMEDIDDK
                     FISKVKKGDIIVATKNFGCGSSREHAPIVIKESGVSCVIASTFARIFFRNSINIGLPI
                     LECEEAANNIDEGDNIEVDFSTGVIKNITKGKEYKAEPFPEFMQNIILNEGLINSIKA
                     NRG"
     gene            11581..12651
                     /gene="leuB"
                     /locus_tag="KR231_003010"
     CDS             11581..12651
                     /gene="leuB"
                     /locus_tag="KR231_003010"
                     /EC_number="1.1.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-isopropylmalate dehydrogenase"
                     /protein_id="HBH0005367.1"
                     /translation="MNCNIAVIKGDGVGPEIIDEGIKVLNKICCKFNHRFDCEYVLAG
                     GCAIDETGEPLPNKTVETCRKNEAVLLGSVGGPKWDKCKGDKRPESGLLKLRESLGLF
                     ANLRPATMYESIKEASPLRTDIVEKGIDFVVVRELTGGIYFGERGRKIIDGIENAYDV
                     EIYNENEIRRIGKRAFEIARNRNKKLISVDKANVLESSRLWRSIMEDLAKEFEDVELS
                     HMYVDNAAMQVVKDPSQFDVIVTNNIFGDIISDEASMITGSIGMLPSASLREDSFGMY
                     EPIHGSAPDIAGKDIVNPIATILSVSMMLRHSFNLEEEAKCIEDAVQSVLNKGYRTID
                     IYNGVGNVVGTREMGELIVNEI"
     gene            13014..13529
                     /locus_tag="KR231_003011"
     CDS             13014..13529
                     /locus_tag="KR231_003011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PaaI family thioesterase"
                     /protein_id="HBH0005368.1"
                     /translation="MDFLAKYKVLKKQNSSKSCLVCGTQNELGLKADFYELENGELVS
                     ICNTKDWHQSYPGRVHGGMSAAILDETIGRAVSINDDQIWGVTVSLELKYKKPVPTDA
                     TIKVVGRITKENRKLFEGTGEIILPNGDIAVTATGKYMKMPIGQIAEGDFSNEEWFFE
                     ESKEKVEYIEL"
     gene            13902..14978
                     /locus_tag="KR231_003012"
     CDS             13902..14978
                     /locus_tag="KR231_003012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine--glyoxylate aminotransferase family
                     protein"
                     /protein_id="HBH0005369.1"
                     /translation="MSKKLFIPGPIDVKEEVLQKMATPMIGHRGKDASMLQKSISEKM
                     QKLFYTNNTILLSTSSGTGLMEGSIRSCTSKKAAVFSCGSFGDRWYKMAVANNVPADI
                     FKVELGEATTPEMVDKVLSTGEYDLITVTHNETSTGIRNPIEEIGEVVKKYEDVIYCV
                     DTVSSAGGIKVEVDKIGIDICITSVQKALGLPPGMSICTFSQKAIDRAKQVPFRGVYL
                     DLLAMYEYLIKKNYQYPSTPSLSHMFALDFQLDNILDEGLDNRFNRHEDMANLVRNWA
                     KKHFQIFTNENHLSNTLTVIENTQGISVSNLNSKLQERGFQIANGYGDLKEKTFRISH
                     MGDYTVEDVQELLDNIDDILGFNK"
     gene            15218..16159
                     /locus_tag="KR231_003013"
     CDS             15218..16159
                     /locus_tag="KR231_003013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-3-phosphoglycerate dehydrogenase"
                     /protein_id="HBH0005370.1"
                     /translation="MYNILVTDGIEKEAARKLRELDFNVIEQFYEKDVLGDKLKDVDV
                     LVVRSATKVTKDVIDKALEGKKLKLIVRGGVGLDNIDVKYAQANGIKVMNTPNASSIS
                     VAELTIGQLFVLARFINTANVTMRDGKWEKKKYKGTEINGKTLGLIGFGRIAKEVAKR
                     AELLGMNVIYTDIMGEAQGFNNYKFCDMEEVLENADFLSLHIPFDKNKGAVITEKEIN
                     KMKKGAYLINCARGGLVDEKDLLKALDEGKLSAAAIDVYEQEPTLNLDLVNHPRVSPT
                     PHIGASTVEAQERIGDEIVNVIQDFFLDFNNLIGVAL"
     gene            16192..17442
                     /locus_tag="KR231_003014"
     CDS             16192..17442
                     /locus_tag="KR231_003014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1015 domain-containing protein"
                     /protein_id="HBH0005371.1"
                     /translation="MATIKPFKAIRPNKYIVDKVAALPYDVMNSKEARRIAEGNPYSF
                     LHIDKSEIDLDENIDLYDEKVYLKARENLDEFRKQEILVKDDKECIYIYKQIMDGRAQ
                     VGIVACISVDESLNGTIKKHEYTRPEKEIDRTKHIKYCDANTGTILVTYKHQRVIDDI
                     INDFMDNNEPLYDFITDDKIEHTVWKIDNDDIIDNLVDKFEKLDYLYIADGHHRTASA
                     ENVAKEMRAKNPNYTGKEEFNYFIAMIAPDENLMVLDYNRVIKDLNGLSEEEFINKIK
                     ENFELEEIEGKEKYKPDKKGTFGMYLGDKWYKMKANKNLLEIEDPVDSLDISILQDYV
                     IDAILGIDNPRVDKRIDFIGGIRGLEELEKRVNEDMKVAFAMYPTSIEDLIRVADANK
                     IMPAKSTWFEPKVRCGLFLHEINE"
BASE COUNT         7111 a         1832 c         3284 g         5845 t
ORIGIN      
        1 aagactacta tattttatga tttaaacaat acttatgatg tattgttaga tacagataca
       61 ggagttttat tcaatttaaa tgtatttgct ataagtcaag acaatagtaa gcacatattg
      121 ttttcagcaa ttatatcaat ttttgcatat ccaatatacc tattttgtac ttcaatagca
      181 aatcctggga caacagattt taatagtgcc tatgggtttg gactaatttg tctacaaata
      241 ataactagtg ctatgtcaat aactttagtc tttaatcata ttaaaaagat aaaaatgcag
      301 agattaactt taattttact tactatgata atgatatttt cttttccaca gttatttatg
      361 actttaaatg tagagagatt tatatatagc caattttcat taatattttt catagttatt
      421 gcaaataaga tgaaaggaaa aaattcttat ttagtagaat tagcagctat tcctctattt
      481 ggaataacta ttagtaatat atatttgtat ttttttaata tgatatttga gtttaaatta
      541 aaaataggaa aaatgttaaa acatttaatt acatttatcc taatggcata tatttgtgta
      601 gtttcaacaa agtcttatga gagttttatg aaccttggaa atgtaataca gtatgatacg
      661 aaatttataa gtggagaacc aattttggaa aagattgcaa tgattataga gagattattg
      721 tattcggttt tttattttcc tggagcaagt attaaaaaag ggttattttt gcaaaatgga
      781 gaagttgcta caataccagt aattcttaca ttattagctt tatgtttttg tgttttatca
      841 gttattgaaa attcagaaaa aagagttcct aagctatgta tgggaataat tatattcaat
      901 ctaactttac atggtatagt aggatataat ctagtcaatt caagtattat ggctataaat
      961 tttagttttg cagttataat tttattggct tactttacga aagcgcttag aaaaaatgaa
     1021 aagaatatgt ataatatatt tctatcgctg ttattggtta ctatagtaat cagtaatgtc
     1081 aatggattta tagaaatttt aaacataggg ataaaatcat atcctgttta aaaaataata
     1141 ttgaaagggt agtaagttta tgaaacagac caatacaagt ataaggcttc ttactaaaat
     1201 ttcagattat ataaagttaa tgagaataaa gcaatatata aagaatttct ttgtattttc
     1261 agctataatt ttttcaaaca acatactaaa tataaattta tttttaaata cgtttattgc
     1321 gtttgtgtgt ttttgtctaa tgtcatcatc agtatatgca ctgaatgatg ctatagacat
     1381 ggataaagat aaaaaacatc ctaaaaaatg taatagacca gtggcaagtg gaagaataag
     1441 caaaaaaagt gctaatatac tatttgtagt attagcttta atttcagtct gtttatcaac
     1501 agttgttagt tttaatcttt ctataattct cagtctctat ttgataaaca atatattata
     1561 ttctcttaaa ctaaagaata taatactatt agatgtgttt tcaatatctc ttggttttat
     1621 acttagggtt tatgcaggat gtgtagccat aagtgttagt ttatcaaatt ggataatttt
     1681 atgtacattt ttcttatctc tgtacttagc tcttggaaaa cgtaaaaaag aaatagaaac
     1741 tctaagagat gatgcagttg aacatagaaa aatattggaa gattatgaca tagaaaatct
     1801 aaatcaaatg atgatagtta tattaagttc tacaattgta tgttatgcat tgtattctac
     1861 aagtaatcca gaaaagccac atatgatatt tacaacaata tttgtagttt atggtgtact
     1921 tagatataat tatataatta acactacaaa tgaaaataat cctactgata ttgtcttaaa
     1981 agataatgct ttaaaaataa acgtaatctt atggataatt acatgtttaa taatattgat
     2041 tttttagtga tatttttagt gataggatgg ggaaatactt atgaaaaaaa gtgtattatt
     2101 acttgatgta gattatactg ttataaatac tgatagcatg atagattttt ttatttactc
     2161 tttaaaaaat aaaaccttta aaactattat aaagttacca tacattattt ttattctatt
     2221 tatgtattta attagaataa taccattgaa gaaggcaaaa gaggcaatct tttatccaat
     2281 agtagatttt agtgaagaag atttaaaaaa gttttttgat gattgcataa tgaaaaaaat
     2341 taacgaatct atgaaaaagg ttatttacaa aaataaagaa gaagataatg ttataattat
     2401 gataactgca tctccatatg catatatgaa atattttaag tattatggtc ttgcagacga
     2461 ggttataggc acggagtttt tttatgaaaa ttcaagatat aaaaataaat tcattggaga
     2521 aaactgtaag ggaattgaaa aagtaaaaag aataaaggct gtattaggta aacttgggat
     2581 agagattgat tatgaaaatt catatgcata ttcagactct aagagtgatt taccaatgct
     2641 ttcattgact aaaaatgcat ttttagttag taaaaaggat ggtgaggtta tagagcaaat
     2701 aaattcataa cttaatgtca cttagaatag gagggaatag tttgggatat ttacacatat
     2761 taattttatc tatggttcct gtaacagaat tgaggggagc cattcctata ggtattgcaa
     2821 tgggcttaaa tcctatatgg gtttatgtat ttagtgtaat aggttctaca ttggtatcga
     2881 ttcccttgat attgacattc agacatgtat tacaattttt aagagggaag aaactattta
     2941 aagggattgc tgatgtaatt gatagaaaaa taaactcaag aatgaagaaa ttaaaaagtg
     3001 tttcgataat tggtataata ctatttgtag gtataccact gccaactaca ggaacgtgga
     3061 ctgcatctgc tatagcttcc atattaaaaa tgagaataaa agatgctttt atgggagtat
     3121 ttcttggcaa tttgttatca ggggttatag tttcagctct ttctttacat ataatataaa
     3181 actatctaag taatatactt ggatagtttt tttatgagta tgtgtgaaaa atttttaata
     3241 ataaataaaa aatgagataa agtatttaac ttcagttagt tctaaaatgt ttactatggc
     3301 aaaagaaata tagtatagta ttacttgtag ggaaagtact ctaaatttgt ctgctaataa
     3361 aatgaaattt ttatatagaa taaaatttta gtgatacatt ttaattattg gattgaggag
     3421 gttttaaaat ggaaaattca aacactaact taggtagtga aagtgtgggt aaattattat
     3481 ttaaacttgc tacacctgct attatcgcac aaattgtaaa tgttttatac aacatagtcg
     3541 ataggatttt tattggtaga atggaaaatg gagaagttgc tatggctggt gttggagtgg
     3601 catttccaat aataattata ataactgcat gtagttattt aatcggtatg ggaggaggtc
     3661 cattagctgc tataaaaatg ggtgagcaaa acaatgatga ggcagagaaa ataatgagta
     3721 acagtttttc tgtactggtg attttagcaa tacttttgac tataggtttt aagattggaa
     3781 aagagccttt actttggatg tttggagcaa gtgaatctac aattggatat tcaatggact
     3841 atttaaatat ttatttaata ggtacagtgt ttgttcagat ttcaatgggt atgaatactt
     3901 ttataaatac ccaagggttt gctacaactg gaatgatgac agttgctata ggtgctttaa
     3961 taaacataat acttgacccg atttttatat ttggctttaa tatgggtgta aaaggagctg
     4021 cattagctac tataattgca caaggcgttt ctgctatttg ggtacttatg tttctctttg
     4081 gaaagaaaag tatacttaaa ataaaaaaga agtatatgat accaaaagca agtatcatct
     4141 taccagtgct tggtttggga atctctccat ttataatgca atctacagaa agtttagtac
     4201 ttatagcctt aaatagtaaa ttacaaatgt atggaggaga tttagcagta ggttcaatgg
     4261 ctataatgag cagtataatg caaattctta tgcttcctaa tatgggggtt acacaaggag
     4321 cacaaccaat aataagttat aattatggtt caggtcaact tgatagagta aaaaagacat
     4381 ttaagttgtg tttgttgtca tgttttacat attctactat tttatggctt ttattaatga
     4441 tatttcctga attttttgtt agtatattta ataagaatcc gcagttactt agtatgacta
     4501 gttggagtat aaaaatatat tttgctggtg cttttatgtt tgggattcaa atagcttgtc
     4561 aacagacatt tttagcactt ggaaaagcaa caatatcttt ggttttagct ctacttagaa
     4621 agattgtact tttaatacct ttaatattta tacttccaac attctttaat gaaaaacttt
     4681 ttgcagtaat tttagcagag ccagttgcag atataacagc tgctactata acagcaattt
     4741 ctttctttat attttataaa tgttttctat caaaacctaa agcaataaaa gaataagata
     4801 tacaatataa attttttatg aaaatatttt attagataaa aattagaatt tgtattttaa
     4861 tttaataaga tattttctat aatgtataaa tatatgaagt tgaatttatt ttaaaaatta
     4921 tagtaagaaa aatgtaagta tttgcaatat taatggtata atatttacag atatgataat
     4981 caataagagg aaaggatgtt tataatggaa aatgatttaa caatgcaaga attacttgac
     5041 cagcaagaac aagtattcag caaagtgaaa gttggagaat tgacaactgg aaaaataact
     5101 gcagtgagaa atgatgaagt acaattagga ttagactatg ggtttgatgg aataatacct
     5161 ataagtgaat tgaacataga aaaaaatcaa tatatagaag atatatacca cataggtgat
     5221 gaaataactg ctgtaataac aaaagtatct caaaaagatg gtacaataac tttatctaaa
     5281 ttacaacttg acaaaagaaa tgattttgcc gagttacaaa aggcttatga tgaacataga
     5341 ataataactg taaatgttga aaagaatata gataaaggtg tatttgctaa ttacaataca
     5401 tatacatttt ttataccaat ttctcaactt gatacaaaat ttattacaga tacatctaaa
     5461 tttgttggtc ttaacttaga agtttatata aaagaattgg atgttagaaa aaatagactt
     5521 gtagcatctc atagagatgt attacaagag cgtataaata aagagagaga agaaagaaga
     5581 gctcaaatta aggcagaaaa agaagctgaa agagcaagaa ttaagcaaga aagagaagaa
     5641 gaaaaagctc gtatcaaagc agctaaagaa gacttattta attctcttga agttggacaa
     5701 aaaagagatg gtaaggtgac aaagataatg ccttatggtg catttgtgga tattggtggg
     5761 attgaaggat tagcacatat aaataattta gcttggacaa gagttgaaag tgttgaagat
     5821 gttgtttcag agggacaaga agtagaagtt tatgtgttgg atgtaaataa agagactaaa
     5881 aaaattgcct tggcattaaa agacataaat aatgaccctt gggatttaat agcaaaagaa
     5941 gtacaaattg atgatgttgt caatgctaaa gttcttagaa taatagaaaa aggggctttt
     6001 gttcaaatta aagaaggtgt agatgcgtat ttaccaatat ctgaattgag tgatactaga
     6061 gtggctaaag ttactaatgt tgttaatatt ggagatgagg ttaaagttaa gattcttgat
     6121 tttaaaccaa agactaagag aatgttggtt tcaataaaag aagcaactag agagccagaa
     6181 gaggatataa cagaatacct agaagtagag gaatctttag gaagtattgg agaattattt
     6241 aaagataaat ttaaagattt agaagtgtaa aataattgaa aatggggctg ttttaaaacg
     6301 ttacactgtc tattatgaca gctttagttt tgaaatagcc ctttagctat tttcacgaat
     6361 ttatgtaaaa tattaggagg aaatttaatg aaaaagtcta ttatggatgt acattgtcac
     6421 actctaataa gtggacatgc acatagtact ttcaaggaaa atgtcgaaga ggcgagtaag
     6481 aagaatataa aatacttagg aatatcagac catggaccta atatgccagg aggaccacat
     6541 ccattctatt tttataattt gcatttgctt ccacgtgaag tgcaaggcgt aaagattctt
     6601 agaggaatag aaggaaatat aatggattat aatggtaatt tagatgttca agaagatatg
     6661 ttgcaacatt tggattatat aatcgcaagt ttgcatagac cttgtatagc ttctggtaca
     6721 aaagaagaaa atacaaatgc tattttaaaa gttatggata aacctaaggt aaaaataatt
     6781 ggacatccag atgacagtag gtatccttta gattatgaac ctatagtaaa aaaagctaaa
     6841 gataaaaata tccttttaga aataaataat tcatcattaa gttcaaactc tcatagaacg
     6901 ggtacttggg aaaatgtaag tcatatgttg acattgtgta aaacatatgg tgcaagagta
     6961 attcttggta ctgactctca tatatgttat tctataggag aatttgaaaa tgcagaaaaa
     7021 gttttagaag cagtagattt tccagatgaa ttagtcataa attatcatga agatgaaatt
     7081 atagaatttt ttgatataaa tttttagaat cttgggagtg aaaaaatttg agtaaaaata
     7141 agtttatcta tatgaattat tatgacaatg gttattttaa aaaaggaatg actatatata
     7201 tggttttagc acttataatt ttagctacaa tttttatata ttcaacgaca atattatata
     7261 ttttatgtat aataacagca gtttttctat ttaaacaagg tcgtgatttt tcaaataaat
     7321 atgagggaaa agtatatatt actctcgata atcattcaat attaataaat aatcaatgta
     7381 tattcagtat aaaatctaaa caaagtcaaa agtttaatta taagataata gaaaaaatag
     7441 aagtagtaaa aaatatatta aatatataca ctaacgaatc taattataaa attagattaa
     7501 gggcattgag tttggaagat gaaaaaaaat tattgaatat catagatgaa aagatgaaaa
     7561 agtttaaggc ataatatcat actgttttca atagttagca tgttttatag aattgcttat
     7621 caaaaataaa aaattgagat aattattttt tgtgttgaca atacatttta atgtgtatat
     7681 aataactatt aaatcaaaat atttagaaaa tttaaatgat taaaaaagtg atgaatagaa
     7741 gtagtaagaa caatgaaact ttcagagagc taaaggatgg tgtgatttag tagttgatag
     7801 ttctgaactt gtctaggagc tgttttctaa gatttaaatc ttagaataat cggagtaatt
     7861 ccacgttata ggaaatatag tcattataat tattgtattg gctattacta agggagcttt
     7921 ttagaaagct aaatagagtg gtaccgcgag caaaacctcg tctctaattt tattagagat
     7981 gaggtttttt ttattctaat gataaaattg acatttatcc ttatgaattg tgcaggattg
     8041 cgtcgatatg aggtatactg aatacaaaaa acagaaaaag ggggaaataa catgaagtgt
     8101 ggaaagtata aaaaatatga taaaatgcaa atagtaaatc gtaaatggcc agataatgaa
     8161 atatttaagg ctccaatttg gtgtagtgtc gatttaagag acggaaatca gtcactgcca
     8221 acacctatga gtgtaaatga aaaagtcaga atgttcaaaa tgcttattga tacaggattt
     8281 aaagaaatag aggtaggatt tccatcagca tcaaatacag agtatacatt tttaagaaaa
     8341 ttaatagatg agaatatgat tccagatgat gtaactatac aagtacttac acaatctagg
     8401 gctcatctta tagaaaaaac atttgaatca ataaggggat gtaaaaaagc aattatacat
     8461 ttatataact ctacatctgt tcttcaaaga gatgtggttt ttaatatgag taaacaagaa
     8521 ataatagata tagcagttga aggagcaaaa ttatttaatg aagaagtaaa aaaatatcca
     8581 gaaacagaat ttacttttga atattcacca gagagtttta caggaacaga gatggattat
     8641 gcacttgaaa tatgtgaggc agtgatagat gtttggaaac caactcctca aaaaaaagta
     8701 ataataaatc ttccatcaac agttgaaatg gcaacaccaa acgtatatgc agaccaaata
     8761 gaatggtttt gtaaaaatat aagttgtagg gattctatta tactaagttt gcatactcac
     8821 aatgatagag gaacttgtac ggctgcaagt gaacttggat tattggctgg tgccgataga
     8881 cttgaaggaa cactatttgg aaatggtgaa agaactggga atatggatat agtaaatgtg
     8941 ggacttaatc tttatacaca aggaatagac ccagagctag attttagcaa tatagataag
     9001 ataataggta tatatgaaga ctgtacaaaa cttatggtac atgatagaca tccatatgca
     9061 ggtaatcttg tacattgtgc tttttcaggt tcacatcaag atgctattag aaaaggcatg
     9121 atagcaatga aaaacagaga taatgattac tgggaagttc catatttacc aatagaccct
     9181 catgatattg gaagagaata caaagaaatt ataaggataa atagccaatc tggaaaagga
     9241 ggagctgttt atataatgga aacagattat ggatttatga tacctaaaaa tatgcattct
     9301 gattttggaa atgtagtcaa aatggaatct gatagaattg gggaagaact tagtagtgaa
     9361 gcaatattta atttgtttaa gaaagaatat attgaagttg agagccctta taaagttaag
     9421 aagtataaaa taaaatcaat ggatgaatta aactatgaaa atgatgattc taatgatact
     9481 aatatgattg agatgactgc aagaataagt tatatgggaa atgaacaaag gattgttggt
     9541 ataggaaatg gacctgtaga ttcatttaat aatgcactaa agcaatgtgg catgaaagat
     9601 tataaattta gatattactg ggaacatgca ttagaggaag ggtcacattc aagaggggta
     9661 gcttatgtag gaatagagca caataatgaa gtctattttg gtgtaagtat atcggaaaac
     9721 ataaatacag cagctattaa tgcacttatg aatgcaataa ataaaagtta tattgaggag
     9781 gaaataaaaa atggggatga ctatgacgca gaaaatatta gccaaacatg ctaaattaaa
     9841 tgaagttaag aaagggcaat taatcgaagc agatttagat gtagttttag gtaatgatat
     9901 aacatcacca gtagccatta gagaatttga aaaattagga attgaagatg tttatgataa
     9961 gactaaagta gtgatggttt tagaccactt tacacctaat aaagatataa agagtgcaga
    10021 acaatgtaaa tttacaagaa gtttcgcaaa atcaaaagga gttgtaaatt tttttgatgt
    10081 aggagatatg ggaatagagc atgttcttct tcctgaaaaa ggtatagtaa ctgctggaga
    10141 tgtaattata ggtgctgact ctcatacttg cacatatgga gcattaggag cattttctac
    10201 tggtgtaggt tcaactgata tgggagcagg tatggctaca ggaaaatgtt ggtttaaggt
    10261 tcctggagca ataaaatttg ttttgaagaa taaaccaaat aaatggataa gtggtaaaga
    10321 tataatactt catataatag gggagatagg tgttgatgga gcactttaca agtcaatgga
    10381 attttgtgga gatggagtag aatacttatc tatggatgat agatttacta tttgtaatat
    10441 ggcaatagaa gcaggagcaa aaaatggaat ttttccagta gacgataaga ctatggaata
    10501 tataaattca cataagtgtt caactatgac aaaagatgta aatatatatg aagcagatga
    10561 agatgcagtc tatgatgaag tatacgaaat agatttagct gaactaaaag aaacagtagc
    10621 ctttcctcat cttcctgaaa atactagaac agtagatgag atagataagg atataaagat
    10681 agaccaagtt gtaataggct cttgtacaaa tggaagaata tcagaccttg aagtagtagc
    10741 tgagataatg aaaggcaaaa aagtagcaga tggagttaga gttatgatat ttcctggaac
    10801 tcaaaaagta tatcttgaag ctatagaaaa agggtatatt accactttta tagaggcagg
    10861 agcagcagtt tctacaccaa cttgtggtcc atgtctaggg ggacatatgg gtatacttgc
    10921 agcaggagaa aaatccattt caacaacaaa taggaatttc gtaggaagaa tggggcatgt
    10981 tgattcagag gtgtatcttg caagcccagc tgtagcagca gcatcagcta taactggaaa
    11041 aatatcaaaa ccatcagaaa taatttaagg gaggtaaaat ttatgattgc caatggaagt
    11101 gtttttaaat tcggtgacaa tatagataca gatgtaataa taccagctag atatttaaat
    11161 atagctgatt ataaagaact agcaacgcat tgtatggagg atattgatga taaatttatt
    11221 tctaaggtaa aaaaaggaga tattatagtt gcaactaaaa actttggttg tggttcatca
    11281 agagaacatg caccaattgt aataaaagaa agtggagtat cctgtgtgat tgcttctact
    11341 tttgctagaa tattttttag aaactctata aatatagggc ttcctatact tgaatgtgaa
    11401 gaagctgcca ataacataga tgaaggggat aatatagaag tagatttttc tacaggtgtg
    11461 ataaaaaata taacaaaagg aaaagaatat aaagcagaac catttcctga gtttatgcaa
    11521 aatattatat taaatgaagg cttaattaac tcaataaaag caaatagggg gtagtggagt
    11581 atgaattgta atatagcagt cataaaaggt gatggtgttg gaccggaaat tatagatgaa
    11641 ggtataaagg ttctaaataa aatttgttgt aaatttaatc atagattcga ttgtgaatat
    11701 gtattagctg gaggatgcgc gattgatgaa actggagaac ctctacctaa taaaactgtt
    11761 gaaacttgtc gaaaaaacga agctgtattg cttggttctg ttggaggacc aaagtgggat
    11821 aaatgtaagg gagataaaag accagagtct ggtcttttaa aattaagaga gtcattgggt
    11881 ttatttgcaa atttaagacc agctacaatg tatgaaagta taaaagaagc ttcaccactt
    11941 agaacggata tagttgagaa aggcattgat tttgttgttg taagggaatt aacagggggc
    12001 atttattttg gagaacgtgg aagaaaaatc attgatggta tcgaaaatgc ttatgatgta
    12061 gaaatatata acgaaaatga aataagaaga attggtaaga gagcttttga aatagccaga
    12121 aatagaaata aaaaacttat aagtgtagat aaggcaaatg tgcttgagag ttcaagactt
    12181 tggagaagta taatggaaga cttagctaaa gagtttgaag atgtagaact gtcacatatg
    12241 tatgttgata atgctgctat gcaagttgta aaagacccta gccaatttga tgtaatagtg
    12301 actaataata tatttggaga tataatatct gatgaagcat ctatgattac gggttctata
    12361 ggtatgttac catcagcatc acttagagaa gatagttttg gtatgtatga accaatacat
    12421 ggaagtgcac ctgatatagc tggaaaagat attgtaaatc caattgcgac tattctatct
    12481 gtaagcatga tgttaagaca tagttttaac ttagaagaag aagctaagtg tattgaagat
    12541 gctgtacaaa gtgtactcaa taaaggttat agaactattg atatctataa tggtgtggga
    12601 aatgttgtag gaacaaggga aatgggcgaa ttaatagtaa atgaaattta gaattatagt
    12661 ttaatttgaa taatataatt taaatatata acttgtagaa ttagtaaaaa tctattgtag
    12721 tataatttgt tttatgaggg gtgtctcaaa ataaacttta ttagttaatg agacactctt
    12781 ttttatatta agtcaaatat atttttacta ttttaataac gaaaaagagg tttatatcta
    12841 ctttgagttt ctattttgat aaagttattt tttggaaaat aatactttaa attaaactta
    12901 tcatattgaa gtagcctatt tttattatta gaagtttgca gggattttat taatattata
    12961 taatatattt tagaattatt taatattaag cgactactaa tgtcggttag gagatggatt
    13021 ttttggcaaa gtataaagtt ttgaagaagc aaaatagtag taaatcttgt ttagtttgtg
    13081 gaacacaaaa tgagctagga cttaaagcag atttttatga acttgaaaat ggagagcttg
    13141 tatcaatttg taatacaaag gattggcatc aaagttatcc tgggagagtt catggaggta
    13201 tgtctgctgc aatattggat gagactattg gaagagctgt aagtataaat gatgaccaaa
    13261 tatggggagt aacagtatct ttagagttga aatataagaa accagtacca acagatgcta
    13321 ctataaaagt tgttggaaga ataactaaag aaaacagaaa attatttgaa ggtacaggag
    13381 aaataattct accaaatgga gatatagcag tgacagcaac tggaaagtat atgaaaatgc
    13441 ctattggaca aattgcagaa ggtgattttt ctaatgaaga atggtttttt gaagaatcga
    13501 aagaaaaagt ggaatatatt gaactttgat taaataaaaa ttttacattt taaaacataa
    13561 attttatatt tagaaaaaat aaaattcaaa aatacaataa aaatacaaga taaaaataaa
    13621 ttagttatac taaaaagatt tatcgtaata gcgtcaaatt tacatactaa aaaaattaat
    13681 ttatatagat aaaaagtata ttttttttga gagaataatt cagaaaattc agacttatga
    13741 aaaggtagaa aatgaatgtt ttcataaaat atataaaata aattatatat aaaaaataaa
    13801 ttttatgttg acatagttaa ttcagcttga tattatagtt attaaaaata aggacagtaa
    13861 aaacgctatc catattacaa actaaaaagg ggggaattat aatgagtaag aaattattta
    13921 ttcctggtcc tattgatgtt aaagaagaag tcttgcaaaa gatggctaca ccaatgatag
    13981 gacatagagg aaaagatgca tctatgctcc aaaagagtat aagtgaaaag atgcaaaaac
    14041 tattctatac aaacaacacg atacttttat ccacgtcatc cggaactggt ttaatggaag
    14101 gctccattcg ttcctgtaca tccaaaaagg cagcagtatt ttcctgtgga tcctttggtg
    14161 atagatggta caaaatggca gtggctaata atgtcccagc ggatatattt aaagttgaat
    14221 taggagaggc aacaacgcca gaaatggttg ataaggtgct ttctaccgga gaatacgatt
    14281 taataactgt aactcacaat gaaacttcaa ctggaataag aaatccaata gaagaaattg
    14341 gagaagttgt taaaaagtat gaagatgtaa tctactgtgt agatactgta agttcagccg
    14401 gtggaataaa agtcgaggtt gataagattg gaatagatat ttgtataaca tcagtacaaa
    14461 aagcactggg attaccacca ggaatgtcta tttgcacatt ttctcaaaaa gcaatcgata
    14521 gagctaagca agtacctttt agaggagtat atcttgattt gttagcaatg tatgaatact
    14581 taatcaagaa aaactaccaa tacccttcaa caccatctct ttctcacatg ttcgctttag
    14641 atttccaatt agataatata ttagatgaag gcctagataa cagattcaac agacatgaag
    14701 acatggcaaa cttagttaga aactgggcta aaaaacactt ccaaattttt accaatgaaa
    14761 atcacttatc caatacactt actgttatag aaaatactca aggtattagt gtatcaaatt
    14821 taaattcaaa attacaagaa cgaggattcc aaatagcaaa tggctatgga gatttaaaag
    14881 aaaaaacttt tagaatttca catatgggtg actatactgt cgaagatgta caagaattat
    14941 tagataatat tgatgatata ttaggtttta ataaataata ttgtaaaaat atgtatgttt
    15001 taagataaat ttagaatata taataaataa tattttataa aaattacata ttaaattttt
    15061 aacaaacaat aggaaaattt gatatgactt taataaaaaa atattttgaa aattatataa
    15121 acagaaagtt aaattaagta aagtttttta ttgatgaaaa tactttaaaa aataaaaatt
    15181 ggaaaaatta agtgaataaa aattggagga gtttgttatg tataatatat tagttactga
    15241 tggaatagag aaagaagcag cgagaaaatt gagagagtta gattttaatg tgatagagca
    15301 gttttatgaa aaagatgttt taggagataa acttaaagat gttgatgtac ttgtagtacg
    15361 ttcagctact aaagttacta aagatgtaat agataaagca ttagagggta aaaagttgaa
    15421 gttgatagta agaggtggag taggtctgga taatatagat gttaaatatg ctcaagctaa
    15481 tggcataaaa gttatgaata ctccaaatgc aagcagtata tctgttgcag agcttacaat
    15541 aggtcaatta tttgttcttg caagattcat aaatactgca aatgtaacta tgagagatgg
    15601 aaaatgggag aagaaaaagt ataaaggtac agaaattaat ggaaagacac ttggacttat
    15661 aggttttgga agaattgcaa aagaagttgc aaagagagca gaattattag gtatgaatgt
    15721 tatatatact gacataatgg gtgaggcgca aggctttaac aattataaat tctgtgatat
    15781 ggaagaagtt ttagaaaatg cagatttctt atctttacac ataccatttg ataagaataa
    15841 gggggcagta ataactgaaa aagaaataaa taagatgaag aaaggggctt atttaataaa
    15901 ctgtgcaaga ggcggtttag ttgatgaaaa agatttacta aaagcattag atgaaggtaa
    15961 attatcagca gctgctatag atgtttatga acaagaacct acattaaatt tagacttagt
    16021 aaatcatcca agagtttctc ctacacctca tattggggca tctacagtag aagctcaaga
    16081 aagaatagga gacgaaatag taaatgtgat tcaagatttc tttcttgact tcaacaatct
    16141 aataggggta gcattataaa atattttgta taattaggga ggaaattagt aatggcaacg
    16201 attaaaccat ttaaggcgat tagaccaaat aaatatatag tagataaagt agcagcactt
    16261 ccttacgatg ttatgaatag taaagaagct agaagaattg cagaagggaa tccatattca
    16321 tttttgcata tagataaatc agaaattgat ttagatgaaa atatagattt atatgatgaa
    16381 aaagtttatt taaaagcgcg agaaaattta gatgagtttc gaaaacaaga aattctagta
    16441 aaagatgaca aagagtgtat atatatatat aaacaaatca tggatggtag agctcaagtt
    16501 ggtatagtag catgtatatc agttgatgaa agcttgaatg gaacaataaa aaaacatgag
    16561 tacactcgac cagaaaagga aattgataga actaaacaca taaaatactg tgatgctaat
    16621 acgggaacta tacttgtaac ttacaaacat caaagggtga tagatgatat aatcaatgat
    16681 tttatggata ataatgaacc tttatatgat ttcataacag atgacaagat agagcataca
    16741 gtatggaaga ttgataatga tgatataata gataacctag tagataaatt tgaaaaatta
    16801 gattatctat acattgcaga tggtcatcat aggacagctt cagcagaaaa tgtagccaaa
    16861 gaaatgagag ctaaaaatcc aaattatact ggaaaagaag aatttaatta cttcatagca
    16921 atgattgcac cagatgagaa tttaatggtt ttggattata atagggttat caaagactta
    16981 aatggtttaa gcgaggaaga atttataaat aaaataaaag aaaattttga actagaagaa
    17041 atagaaggaa aagaaaaata taaacctgac aaaaaaggaa ctttcggaat gtacctaggt
    17101 gataagtggt ataaaatgaa agcaaataaa aatttattag aaatagaaga ccctgttgac
    17161 tcattagaca tttctatatt acaagactat gttattgatg ctattttagg aattgataat
    17221 cctagagtag ataaaagaat tgattttatc ggtggaatta gaggtcttga agaattagaa
    17281 aaaagagtta atgaagatat gaaagtagca tttgcaatgt atcctactag tattgaagat
    17341 ttaataagag tagcagatgc aaataagata atgccagcta agtcaacatg gtttgaacct
    17401 aaagtaagat gtggtctatt cttacatgaa ataaatgaat aattaataaa gggctaaaaa
    17461 gtgcacaatt cactttttag cccttgtttt tttgattgaa aatcgtatgt ggaatataaa
    17521 ttctataagt tgatattctt aataatagtt accttttttt tagaaatgga taattttagg
    17581 atatagatag tcatattcta tgctataatt gaggatgaaa attcatataa ttgtatttgt
    17641 atatttataa ggttttaaat gtgtatttat aatagtactg ttatatattt ttattataat
    17701 tataaaaaag ttaataaaaa aagtgatttt gaaatttata ttttattttt ataaatataa
    17761 ttattatatt tataaaaata aaatagtaaa aggatattat aatattttac tagaattatt
    17821 atctggtaac ttaagttttg agtattaatc taaagtatat gtttttatat ggtttaaatt
    17881 ttatgtatac aaaattaatt tgctaactga atcatataaa aaaaaacaaa atatttttta
    17941 gagggaatga ttagatagaa tttttttgtt atgaaattaa ttgaagagta attaattaga
    18001 aaaggaatga ataataatga atatattaca ttattacttt ttgataaatc aaaaataaag
    18061 ttataatttt ta
//
LOCUS       DAEPHU010000078        17777 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 01A10CD0081
            SAMN05941466-rid12468953.denovo.078, whole genome shotgun sequence.
ACCESSION   DAEPHU010000078 DAEPHU010000000
VERSION     DAEPHU010000078.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941466
            Sequence Read Archive: SRR6291087
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 17777)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17777)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068158.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 22:43:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,892
            CDSs (total)                      :: 3,805
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 87
            rRNAs                             :: 8, 1, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 55
            CDSs (without protein)            :: 55
            Pseudo Genes (ambiguous residues) :: 0 of 55
            Pseudo Genes (frameshifted)       :: 21 of 55
            Pseudo Genes (incomplete)         :: 28 of 55
            Pseudo Genes (internal stop)      :: 16 of 55
            Pseudo Genes (multiple problems)  :: 8 of 55
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17777
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941466-rid12468953.denovo.078"
                     /strain="01A10CD0081"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            <1..596
                     /locus_tag="KR231_003015"
     CDS             <1..596
                     /locus_tag="KR231_003015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="DUF2953 domain-containing protein"
                     /protein_id="HBH0005372.1"
                     /translation="IIAVIFIISVTMLILISHINILIIADIKNKDICLKLNIKYMFNL
                     ININRQLYPAENSKNNDKKEGMKNNIDSSILLADDLLSIYRLLKKIKIHELYSNINFG
                     TGNIGLTSSVYVLINTLYGNLFNMIDAEKMYLNVNPDFTKDYVLGNIRIHIRPRIKAL
                     FNIIIMINKIMNKNKGNKEGDSNESNRFDTESYGNNS"
     gene            550..978
                     /gene="ytfJ"
                     /locus_tag="KR231_003016"
     CDS             550..978
                     /gene="ytfJ"
                     /locus_tag="KR231_003016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GerW family sporulation protein"
                     /protein_id="HBH0005373.1"
                     /translation="MRATGSIQSLMETTLETIKGSIDANTIIGDPIKTDTTVVVPISK
                     VTIGFGIGGGEYSKGYDDKDREIELKNEKSDTNFAGGSAGAISVQPVAFVVVESGETR
                     IMSLDSNINLVDNILSITPRVLEKIQNISQSNKNQDKNNM"
     gene            1226..1666
                     /locus_tag="KR231_003017"
     CDS             1226..1666
                     /locus_tag="KR231_003017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HBH0005374.1"
                     /translation="MSDKELSILLLESMNNFHNLIKIINNERYKKDKVLTERQFFALV
                     KIRKHDKIELKNLSRDLHVSTSSLCILLNKLVEQEYVYREEDSRDRRNTFYGITKNGE
                     KILDNEILKFVSIISDKMDCLDIDNKDKLFTSLEESKNIIEQLF"
     gene            1682..3133
                     /locus_tag="KR231_003018"
     CDS             1682..3133
                     /locus_tag="KR231_003018"
                     /EC_number="3.4.11.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="leucyl aminopeptidase"
                     /protein_id="HBH0005375.1"
                     /translation="MNIKYSKEILKSLENAITVVALFEGEDVSTTFDKINMISRNFNS
                     KENSIDTVTLIENNNLVNVCLVGFGKRELLNREKIRIIGGNLCKKLKNILKNEAYKSS
                     DVNVLNLNLNSDEIGSFVEGILLGNYKFDKYKTKIKDFERKEVDTITIFTEKEVECQI
                     EKAKILANSTIIARNLVNEPSNVIYPKTLAVETVKLGAEFGFNVDVYEEEKIKALGMD
                     AFFAVSRGSINKPRFIVMRYFGDKESTDILGLVGKGLTYDTGGYSLKSNASMLDMKTD
                     MAGAASVIGAMCAISQSKLKKNVIAVVAACENALSGGSYKPGDIISSMAKKTIEVLNT
                     DAEGRLTLADAIYYIINNEKVTKVVDVATLTGAALTLLGNVATPIVTNNDDFYCELEK
                     AATLSGERVWKMPIYDEFKDMIKGEEADLKNTGGKNAGCITAGAFIGEFVGNTPWIHM
                     DIAGTSTSSKSIGYKAKGATGEPVRTLYYLAEI"
     gene            complement(3224..3892)
                     /locus_tag="KR231_003019"
     CDS             complement(3224..3892)
                     /locus_tag="KR231_003019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896207.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YwaF family protein"
                     /protein_id="HBH0005376.1"
                     /translation="MFKIFLFSSEQFVSLFIFGLFLYYCPKLTKNILPYSYTVEKIIC
                     TLLVIIMALEQLLLISSGNYSTLNSLPIGINYICIYLCIAILIFKQYHLFNIFFSWSL
                     VCSVGELIFSKNLGYEFPSLIYFIFIFSKCLIIYADIYMVDVRKFRVNRYALRDNLAI
                     CFIYFSFIFLLNTFTNSRYYYGFLSHSTTAIFTFIFVTSIMYIPALLFNRDTFILEKK
                     KKSK"
     gene            4161..4301
                     /locus_tag="KR231_003020"
     CDS             4161..4301
                     /locus_tag="KR231_003020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0005377.1"
                     /translation="MGIIESASKLAEMVHLLAVEKGITDIEAWDEAVKEYSKIYEERR
                     NE"
     gene            complement(4476..4796)
                     /locus_tag="KR231_003021"
     CDS             complement(4476..4796)
                     /locus_tag="KR231_003021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MazG-like family protein"
                     /protein_id="HBH0005378.1"
                     /translation="MKLKTISLPELNNLDPTLESTFIKMGEEQGELAECIGKFRNLSG
                     ENNDLDEVDIIKKTAKELMDVAQTCVTMMFKLEEQYGINLDEIRKEHIKKLEKRGYIK
                     NMDK"
     gene            complement(4916..5653)
                     /locus_tag="KR231_003022"
     CDS             complement(4916..5653)
                     /locus_tag="KR231_003022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent protein deacylase"
                     /protein_id="HBH0005379.1"
                     /translation="MDANSLKDLIANHNNIVFFGGAGVSTESNIPDFRSSTGLFSQKL
                     NKQFTAEQLVSHTFFVRYPEEFFEFYKDKLIYPNAKPNNAHIALAKLEEMGKLKAVIT
                     QNIDGLHQMAGSKNVLELHGSVHRNYCTKCGKFFDLESMLNLGGNIPYCDNCGSIVKP
                     DVVLYEEALDSDVITKTISAISNADLLIIGGTSLAVYPAASFIDYYKGDYIALINKAN
                     TVYDKSASLVINKPIGEVLYEAVLRQI"
     gene            5868..7691
                     /gene="acd"
                     /locus_tag="KR231_003023"
     CDS             5868..7691
                     /gene="acd"
                     /locus_tag="KR231_003023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylglucosaminidase"
                     /protein_id="HBH0005380.1"
                     /translation="MKKKAALATLAMLPLGVVNAHADGDIGIVTINYLNVRNEPTAES
                     SIAFVAKKDDKVLIKDSSNGWYKIKAESGQEGWASSKYIAKSNSDSLRTSTNKEKQVI
                     SNSLNMRNGAGTSYRVITVLKKGQKVEVISESNGWSKIKYDGRLGYVSSSYLGDVSNS
                     TNKSKTKQVNTTSLNVRSGPNTSYGLLGKLPKGSKVEVISESNGWSKIKYNGKDAYVS
                     SMYLSDVSQSNSDNSSQSNDKKNTDKVVNTASLNVRSGPGSTYSKLGKVYKGSKVTVL
                     SESSGWAKINFNNKEAFVVGNYLSTSADTSNNNSNSNSDNSSNSNGNNSSSSGQVNGM
                     SGISGAKIDYKSLSYTLESHISKQVEKAASGGNVIAPSNRKSTPSPEFSTFSAQRTSS
                     FVNASSSDIEYYLNPKNFTNTTKGMMQFLKINSYRDGISESSLNSYLNGLSSSVFKNQ
                     GAAFINAAKKYNIDVVYLVSHAMWETAYGKSTLAQGQTLTSYKGQPLSKPVKVYNFFG
                     IGAIDKSANVSGAEAAYSNGWTSVEATIDGSAKWISQNYVNSSKYNQNTIYKMKWNYD
                     YTWHQYATDVNWANGISGIMENLIGLYGGGSSLVFEVPQYK"
     gene            7906..12204
                     /locus_tag="KR231_003024"
     CDS             7906..12204
                     /locus_tag="KR231_003024"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PolC-type DNA polymerase III"
                     /protein_id="HBH0005381.1"
                     /translation="MESIKEYLDKLEINNSGLGKQLKEVYINRVVYFKEDKIVYFYLT
                     SKDIVSHELLDKFKEELMYKLDYFKDMRMKIRFTGLERKSNKDVIKKYWNNILYILKY
                     LCPSIAGWYKQVEFLCLEEELKIKLPKGIFYERLMKKNVTYVLKTVLSEELGLDLNIT
                     IEKAVDEKVNKERLIRINDREMEEKIRALEIGKVNNCEENEEESYVIKSDVDENLIYG
                     DNANAMIENIVELNASSGTVAVVGDIFDVDTKELKNGKILMIASITDYTSSISCKLFL
                     TDTNKDGVLENVKKGAYLKIKGDIVYDTYQREISMMISGIRKETRIEREDKSEEKRVE
                     LHAHTQMSSMDAICSVKKLVERAAKWGHSAIAITDHGVVQGFPDAMNAGKSNNIKILY
                     GVEGYLVEDDSLIIEDANDKELSQTFVVFDIETTGFSNTNDKITEIGAVKIENFKIVD
                     RFSELINPEKDISYKIQELTGITNELIKDKPTIEEVLPKFMEFVGDSVLVAHNAEFDT
                     GFISQKCREQGLLYNNKKVDTLMLARVMLPNLKRHRLNVVAKELGIPLLNHHRAVDDA
                     EATALIFNKFLQMLTEKGAKTLSDVNNILGKIDYTKLSTNHITLIAKNSIGIKNLYKI
                     ISDAHVNHFFRAPRILRSVLNEYKEGLIIGSACEAGVVFQAVKKNVSDEEMKKIIDLY
                     DYIEVMPIDNNRFMIDKGEVKDEEELRELNRKLIDTAKKFDKIPVATGDVHFLDKHEA
                     VLRKVLKYSQGFKVDEEETYLHFRTTDEMLEEFSYLGEELAYEVVVENSNLIADMVED
                     IKPIPDDTYPPIIEGSDVELREMCYKKAKRIYGDPIPEIVQKRLDRELNSIISNGYAV
                     MYIIAQKLVAKSLSDGYLVGSRGSVGSSFAATMSDITEVNPLPAHYICENEDCKYSFF
                     YEIGEWGSGVDLPDKDCPKCGRKLAKNGHDIPFEVFLGFEGDKEPDIDLNFSGNYQPT
                     IHKYTEELFGEGYVYRAGTIGTVAEKTAFGYARKYVEENNISVPNAEVLRLSNGCTGV
                     KRTSGQHPGGVMVIPDYKDVYDFTPIQYPANDTSCGVITTHFDYHSISGRILKLDILG
                     HDGPTIIRMLEDMTGINITEIPLDDKETMSLFTSTEALGVTPEEINCPIGCLAVPEFG
                     TKFVRQMLLDTKPTTFAELVRISGLSHGTDVWVNNAQDLVREDIVGLKDVISTRDDIM
                     NYLIFKGLPPKMSFTIMESVRKGKGLKPEHIEEMKKNNVPEWYIGSCKKIKYMFPKAH
                     AVAYVMTSFRIAYCKVHYPEAFYATYFTTKVEDFDADLIVKGLDAIKSKINEIESLGN
                     DATTKEKGMLTVLEVALEMYARGIKLLPVDIYKSDATEFIVVGEKTLLPPMAAIQGLG
                     GNAAINIQNERKNGEFISKEDLRKRTKISKTVIETLTNHGSLENMSERNQLSLF"
     gene            12408..12869
                     /locus_tag="KR231_003025"
     CDS             12408..12869
                     /locus_tag="KR231_003025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimP"
                     /protein_id="HBH0005382.1"
                     /translation="MKKNLEATIEEIVTKITDEHGFEMVDVEYVKEAGEYYLRVYIDK
                     EEGISLNECELVSRELSPILDEKDPIKENYFLEVSSPGLDRALKKDRDFVRYQGRDVD
                     LKLYKPLNGCKQFEGELVGLTEDNNIKIIANGKEMEFNRKDVAIVRLAIKF"
     gene            12899..14053
                     /gene="nusA"
                     /locus_tag="KR231_003026"
     CDS             12899..14053
                     /gene="nusA"
                     /locus_tag="KR231_003026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889093.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusA"
                     /protein_id="HBH0005383.1"
                     /translation="MNHEFMEALDELVVDRGIDKEILIDTIEQALLTAYKKNFGSAQN
                     VRVEFDRDKGDIKVFSQRVVVDESDLYDTFLEIELADAREINPNYELGDIIEHEVTPK
                     NFGRIAAQTAKQVVVQRIREAEREIVYNEFIEKENEIVTGEVARANKNVVYVNLGRIE
                     GIMTQSEQIPFENYKAGQKIKFYILEVKKTNKGPQIVVSRSHPGLVKRLFEEEVPEIY
                     EGIVQIKSVAREAGSRTKMAVRSIDEKIDPIGACVGPKGLRVKNIVDELGDEKIDIIK
                     YSEDPAEFISAALSPSKVVRVDIDEDEKSALVIVPDYQLSLAIGKEGQNARLAAKLTN
                     WKIDIKSESQAEQEMLNLENSKEIEAEDVEAEFIDQEELDTSEDNFSEEE"
     gene            14060..14341
                     /locus_tag="KR231_003027"
     CDS             14060..14341
                     /locus_tag="KR231_003027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlxR family protein"
                     /protein_id="HBH0005384.1"
                     /translation="MILKKVKKVPQRKCIACQDRDSKKELIRIVKNKEGKIFLDPTGR
                     ANGRGAYVCKSSECLKKAIKSKALNKAFKIDVPDEVYDNLLMELEEYEK"
     gene            14331..14642
                     /locus_tag="KR231_003028"
     CDS             14331..14642
                     /locus_tag="KR231_003028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal L7Ae/L30e/S12e/Gadd45 family protein"
                     /protein_id="HBH0005385.1"
                     /translation="MKNNKEKVLSFLGLATRAGKIVSGDDSTLLDLKKGKVNLILIAE
                     DASNNTKKLFKDKSTFRNIPYLFFSTKEEIGFAIGKSPRAVVGIKDENFSKKIIELIE
                     I"
     gene            14664..16604
                     /gene="infB"
                     /locus_tag="KR231_003029"
     CDS             14664..16604
                     /gene="infB"
                     /locus_tag="KR231_003029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-2"
                     /protein_id="HBH0005386.1"
                     /translation="MSKTRVYQIAEELNISNEELINKLAELDINVTDKDSVLEGEELE
                     LALEMLGEDLSQENGNVIEIDGKLTVQVLATKLDKSPSEIIMKLMKMGTMATINQEIS
                     FEIAALAAKDYGFELTVAESDDTEALEIEALMEIEEDKEEDLKPRPPVVTVMGHVDHG
                     KTSLLDAIRKTDVISGEAGGITQHIGASEVKINGHKIVFLDTPGHEAFTSMRARGAQV
                     TDIAILVVAADDGIMPQTVEAINHAKAAGVPLIVAINKIDKPGANPDKVKQELADQGL
                     LVEDWGGEVIAVPVSAKKKEGIDTLLEMVLLVAEMEELRANPNKRAVGTVIEAELDKG
                     RGPVATVLVQGGTLTVGDPIVAGVACGKVRAMINAKGKRVKTAGPSTAVEILGLSEVP
                     QGGDQFVEVPTDKIARSVAARRQQIVRDEMLKSTQRLSLDALFSQMSEGSIKDLNIVI
                     KADVQGSVQAVKQSLEKLSNEEVQVKVIHGGVGAVTESDILLAAASNAIIIGFNVRPV
                     PGAESLGEKENVDIRTYTIIYKAIEDIQAAMTGMLDPEYVDEETGKAEIREIYKISGV
                     GTVAGCYVTNGKIFRNCKVRLVRDSIIIHEGELAALKRFKDDVKEVNSGYECGMSFVN
                     YNDIKEGDIVEAYITKEVERKL"
     gene            16647..17027
                     /gene="rbfA"
                     /locus_tag="KR231_003030"
     CDS             16647..17027
                     /gene="rbfA"
                     /locus_tag="KR231_003030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosome-binding factor RbfA"
                     /protein_id="HBH0005387.1"
                     /translation="MASYNRTRRIAEEIRKVVSTMLINGVKDPRITSMVSVTDVEVTN
                     DLRYAYVYVSILGGDEESTLTGLKSAGGYIRREVGKNIKLRYIPEIVFKLDDSIEKGM
                     YMDSLIKRVNEKNAQQNEDENYDE"
     gene            17008..17685
                     /locus_tag="KR231_003031"
                     /pseudo
     CDS             17008..17685
                     /locus_tag="KR231_003031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438308.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DHH family phosphoesterase"
BASE COUNT         7171 a         1928 c         3262 g         5416 t
ORIGIN      
        1 taataatagc tgtaattttt attataagtg taactatgtt gattttaata tctcatataa
       61 acatcttaat aatagctgat ataaaaaaca aagatatttg tttaaagctt aatataaaat
      121 acatgtttaa tttaataaat ataaatagac aactttatcc agctgaaaat agtaaaaata
      181 atgataaaaa agaggggatg aagaataata tagattcaag tatattatta gctgatgacc
      241 ttttgagcat ttatagatta ttaaaaaaga taaaaataca tgaactttat tcaaatatta
      301 attttggaac tggaaatatt ggcttaacat cttctgtata tgtattgata aatactttgt
      361 atggaaattt atttaatatg attgatgcag aaaaaatgta tttaaatgta aatccagatt
      421 ttacaaaaga ttatgtttta ggaaatataa ggatacatat aaggccaaga ataaaagctt
      481 tatttaatat tataataatg attaataaaa ttatgaataa aaataaagga aataaggaag
      541 gtgatagtaa tgagagcaac aggttcgata cagagtctta tggaaacaac tcttgaaaca
      601 attaaaggtt ctatagatgc aaatactatt ataggagacc ctataaaaac agatactaca
      661 gtggttgtac ctatatcaaa ggttacaatt ggctttggta taggaggagg agaatactca
      721 aaaggatatg atgataaaga tagggaaatt gaattaaaaa atgaaaaatc agatacgaat
      781 tttgctggag gtagcgcagg ggctatatct gtacaaccag tagcatttgt agtagttgaa
      841 agtggagaga ctagaataat gagtttagac agtaatatca atctagtgga taatatatta
      901 tctataactc ctagagtatt ggagaaaatt caaaatatat cacaaagtaa taagaatcaa
      961 gataaaaaca atatgtaaga ataaaatatt tttaaatatg tatatagttt taggtaaagt
     1021 agtggggtta gtataaatcc cactattttg ttgtgtactt taaacattta tatctaataa
     1081 gattttagtt taaaacaatt taaatagata ataaagttga tatatagtat aattataaaa
     1141 agaaaagaag tattatatta tagatatata aacgcatttg agatataaga gggagttata
     1201 aatcattagt tttgaggtga atgttatgag cgataaagaa ttatctattt tgttgttaga
     1261 aagtatgaat aattttcata atttaataaa gattattaat aacgaaagat ataaaaaaga
     1321 taaggttctt acagaaagac agttctttgc cttagtaaaa ataagaaaac atgataaaat
     1381 agagcttaaa aatctaagta gagatttgca tgtatctact tctagtctgt gtatactact
     1441 taataaattg gttgagcaag agtatgtata tagggaagaa gatagtagag atagacgaaa
     1501 tactttttat ggaataacta aaaatggaga aaagatattg gataatgaaa tactaaagtt
     1561 tgtatctata ataagtgata aaatggattg cctagatata gataataaag ataaattatt
     1621 tacttctttg gaagagtcta aaaatataat agaacaatta ttttaaaaag gagaatttat
     1681 tatgaatata aagtattcta aagaaatatt aaaaagttta gaaaatgcta taacagtagt
     1741 agctctattt gagggagaag atgtttctac gacatttgat aaaataaata tgataagcag
     1801 aaattttaat tctaaagaaa atagtataga tactgtaaca ttgattgaaa ataacaattt
     1861 ggtaaatgtt tgtcttgttg gttttggtaa gagagagtta ttgaatagag aaaaaattag
     1921 aatcataggt ggtaatttgt gtaaaaaatt aaaaaatata ttgaaaaatg aagcatataa
     1981 gagtagtgat gttaatgtac tgaatcttaa tttaaatagt gatgaaatag gttcttttgt
     2041 agaagggata ttacttggaa attataagtt tgataagtat aagacaaaaa ttaaggattt
     2101 tgaaagaaaa gaagttgata ctataactat atttactgaa aaagaagttg agtgtcaaat
     2161 agaaaaggct aaaatattag ctaattcaac tataatagct agaaatctag ttaatgaacc
     2221 atcaaacgta atatatccaa aaacattagc agtagaaaca gttaaacttg gtgcagagtt
     2281 tgggtttaat gttgatgttt atgaagaaga aaaaataaag gcattgggaa tggatgcttt
     2341 tttcgctgtt tcaagaggct caattaataa accaagattc atagtaatga gatactttgg
     2401 agataaagaa agtacagata tattaggttt agtaggtaaa ggattgactt atgatactgg
     2461 tggatattct ttaaaatcaa atgcttctat gctagatatg aagacagata tggctggtgc
     2521 tgcgagtgtt ataggtgcta tgtgtgctat atctcaaagt aaattaaaga aaaatgttat
     2581 agcagtagtg gctgcatgtg agaatgcttt atcaggaggt tcatacaaac ctggagatat
     2641 aattagttct atggcaaaga aaactattga agttttaaat acggatgcag aaggtagact
     2701 tacattagct gatgcaatat actacattat aaacaatgaa aaagtaacaa aggtggttga
     2761 tgtagctaca ttaactggtg ctgctttaac attgttaggt aatgttgcaa ctcctatagt
     2821 aacaaataat gatgattttt attgtgaatt agaaaaagct gccactttat caggggaaag
     2881 ggtatggaag atgccaattt atgatgaatt taaagatatg ataaaaggag aagaagcaga
     2941 ccttaaaaac actggtggta aaaatgctgg atgtataaca gcaggagctt ttattggtga
     3001 atttgttggg aatactcctt ggatacatat ggatatagcg gggacaagta catcatcaaa
     3061 atcaattgga tacaaagcaa agggggctac aggagaacct gttagaacat tgtactattt
     3121 ggcagaaatc taaaaaacaa ttataaaata taatttataa agccacgtgg atatttttgt
     3181 aatttaagat tatctatgtg gctttatttt ttatttaaat aaattattta ctctttttct
     3241 ttttttcaag tataaaagta tctctattaa ataaaagagc aggtatgtac ataatactag
     3301 taacaaaaat aaacgtaaaa atagcagttg tgctatgact taaaaaacca taatagtacc
     3361 tagagttggt gaatgtgttt agtaaaaata tgaatgaaaa ataaataaaa catatagcta
     3421 agttatctct aagtgcatat ctgttaactc taaattttct aacatcaacc atatatatat
     3481 ctgcataaat tatcaagcac ttagagaaga taaagataaa atatattaag ctaggaaatt
     3541 catagcccaa gtttttagaa aaaatgagtt ctccaactga acaaactaaa ctccaagaaa
     3601 aaaatatatt aaaaagatga tactgcttaa aaattagtat ggctatacac agatatatac
     3661 aaatataatt gattccaatt ggtaaagagt ttagagtact ataattacct gaagaaataa
     3721 gtaataattg ctctagagcc ataattatta caagtaatgt acaaattatc ttctcaactg
     3781 tatagctata aggtaaaata tttttggtta gttttggaca atagtataaa aataatccaa
     3841 atataaagag acttacaaat tgttcactag aaaaaagaaa aattttaaac atataacatt
     3901 ctctcctata ataaatttaa tatgtatcta tataaatata ttcattatat ctcaatttaa
     3961 tatataaaaa agataataat agttagattt tttatatgaa ttttaatagg taaaatatcc
     4021 tattgttttg tagatatatc ctaattatgt caaaaaataa aaaaattttt atttattaga
     4081 gtttttggaa ataataataa cagatattat aattaattaa cagtttttgt aagtatttga
     4141 caatagagag ggtgtaacaa atgggaataa tagagtcagc atcaaaattg gctgagatgg
     4201 ttcatttatt ggctgttgaa aaggggataa ctgatataga agcatgggat gaagctgtga
     4261 aagaatacag caaaatttat gaagaaagaa gaaatgaata gaatgataaa aaatgaaaac
     4321 ttgatgataa aaaataactt tatttaaaga aattcaattt ttatagaagt attaaaaata
     4381 atataaataa aaagatggta tttcaaatgt aagtaaaaaa tcattttggg ataccatcct
     4441 tattatttat tttaataata tataagtaat aaatcttact tatccatatt ttttatgtaa
     4501 cctctttttt ctaacttttt tatatgctcc ttacgtattt catcaagatt aataccatat
     4561 tgttcttcta gcttaaacat catagtaaca catgtctgcg ctacatccat tagttcctta
     4621 gcagttttct ttataatatc aacttcatct aaatcattat tttctccact tagatttctg
     4681 aatttaccta tacattcagc taattcacct tgttcttcac ccattttgat aaatgtagat
     4741 tctagtgttg ggtctaaatt attaagctct ggtaaagata tagtttttag tttcataaaa
     4801 gctcctttca agttattcgt atttatacta aaacatcata acaaaaataa tactaaaaaa
     4861 aaactttaaa ttcaacataa aaacttacat atataataaa aatcatgaaa taaatctata
     4921 tttgtcttaa tacagcctca tataaaactt ctccaatagg tttatttatt acaagagaag
     4981 ctgacttatc atagactgta tttgctttat taataagagc aatataatca cctttgtaat
     5041 aatctataaa acttgctgct gggtacacag ctaatgatgt acctcctata atcaataaat
     5101 cagcattact tatagcagaa attgttttag taatgacatc actgtcaaga gcttcctcat
     5161 aaagtactac atctggtttt actatagaac cacagttgtc acagtaagga atattacctc
     5221 ccagatttaa catagattct aagtcaaaaa acttaccaca tttagtacaa taatttctat
     5281 gtacagaacc atgaagttct agcacatttt tacttccagc catttgatga agtccatcaa
     5341 tattttgagt tatgacagct ttaagcttac ccatttcttc gagttttgct aaagctatat
     5401 gagcattatt gggttttgca ttaggatata ttaatttatc cttataaaat tcaaaaaatt
     5461 cttctggata tctaacaaaa aaagtatgtg aaactaattg ttcagcagta aattgtttat
     5521 tgagtttttg gctaaataat ccagtagaac ttctaaagtc tggaatatta gattcagttg
     5581 aaacacctgc tccaccaaaa aatacaatat tattgtgatt agctattaag tcttttaagc
     5641 tatttgcatc catagttaca cctccaaatt attatatata aattgtacta catattaggt
     5701 cgtttatgtt ttattaattt aaataaatat atagtttaat aagttaaata aagggaatat
     5761 aaataaaatg tatacagagt ataaatagac aatatttact aaaataacaa gttgtcgtat
     5821 aattatatta aaattgtttt agtgtataag aagggcgggg gaagtacgtg aagaaaaaag
     5881 cagctttagc aacattggct atgttaccct taggtgtggt aaatgcacat gctgatggag
     5941 atataggtat agtgactata aattatttaa atgtaagaaa tgaaccaact gccgaaagta
     6001 gcatagcctt tgttgctaaa aaagatgata aagttttgat taaagactct tctaatggat
     6061 ggtataaaat aaaagctgaa tctggacaag aaggttgggc ttcatcaaaa tatatagcaa
     6121 aatcaaatag tgactcttta agaacgtcta caaataaaga aaaacaagtt atttcaaata
     6181 gtttaaatat gagaaatgga gcaggtacaa gttacagagt aataactgta ctaaaaaaag
     6241 gtcaaaaagt agaagtaata tcagagagta atggatggtc taaaatcaaa tatgatggaa
     6301 gactaggata tgtatctagc tcttatttag gagacgtttc aaactcaact aataaatcaa
     6361 aaactaaaca agtgaataca acttcactaa atgtaaggag tggaccaaat acaagttatg
     6421 gtttgttagg caagttgcca aaaggaagta aagtagaagt aatatcagaa agtaatggat
     6481 ggtccaaaat aaagtataat ggaaaagatg cctatgtatc tagtatgtac ttatcggatg
     6541 taagtcaaag taattcagac aattctagtc aaagcaatga taaaaagaat actgataagg
     6601 ttgtaaatac agcttcttta aatgtaagaa gtggaccagg ttctacatat agtaagttgg
     6661 gaaaagttta taaaggaagt aaagtaactg tactatcaga aagtagtgga tgggctaaga
     6721 ttaattttaa caataaagaa gcatttgtag taggcaatta tttatctacc tcagcagata
     6781 cttcaaataa taactcaaat agtaactctg ataacagttc taatagtaat ggtaataatt
     6841 cttcatcatc aggccaagta aatggtatgt caggtataag tggggctaaa attgattata
     6901 aatctttgag ttatacttta gaatctcata taagtaaaca agttgagaaa gcagcatcag
     6961 gaggaaatgt gatagctcca agtaatagga aaagtactcc aagtcctgag tttagtactt
     7021 tttcagctca aagaacaagc tcatttgtaa atgcaagttc aagtgatata gaatattatt
     7081 taaatcctaa gaattttaca aatactacta aaggtatgat gcagttttta aagattaaca
     7141 gttatagaga tggtatttca gaatcaagtc ttaactcgta tcttaatggt ttatcttcta
     7201 gtgtatttaa aaaccaggga gcagccttta taaatgctgc caagaagtat aatatagatg
     7261 ttgtatatct agtatctcat gctatgtggg aaactgctta tggtaagtct acacttgccc
     7321 aaggtcaaac attaacatct tataagggac aacctcttag taagccagtt aaagtataca
     7381 atttttttgg tataggagca atagataaaa gtgctaatgt ttcaggtgca gaagcagcgt
     7441 attccaatgg ctggactagt gtagaagcta caatagatgg ctctgcaaag tggatatcac
     7501 aaaattacgt aaatagttct aagtacaatc agaatactat ctacaagatg aagtggaatt
     7561 atgattatac atggcatcag tatgcaactg atgtaaactg ggctaatgga atttctggaa
     7621 ttatggaaaa tttaattggt ctttatggag gaggaagtag tttggttttt gaagttcctc
     7681 aatataagta atacataaat aaaaaatata gactatgggt agttttcatt ttatttaaat
     7741 tatctatagt ctttttgtat ataatttata atctgtaaat ttaatgttaa caaaactttt
     7801 atgttataat attaattcta agtaaatata agtgagtaat aggtagaaat agataaaaag
     7861 tggtaataat atatataaag ataattttga gaaaggagga tatatatgga aagtattaag
     7921 gaatatttgg ataagttaga aattaataat agtggtcttg gaaagcaact taaagaagtt
     7981 tatataaata gagtagttta ttttaaggaa gataagatag tttattttta tctaacttct
     8041 aaagatattg tttctcatga acttttagat aaatttaaag aagaattgat gtataaactc
     8101 gattatttta aagatatgag gatgaagata agatttactg gtcttgaaag aaaatccaat
     8161 aaagatgtta taaaaaaata ttggaataat atattgtata tattaaagta tctttgtcca
     8221 tctattgcag ggtggtataa acaagtagaa tttctttgtt tagaagaaga attaaaaata
     8281 aaacttccaa aaggtatatt ttatgagcga ttaatgaaaa aaaatgtaac ttatgtactt
     8341 aaaaccgtgc ttagcgaaga gttgggatta gatttaaata taacaataga aaaagctgtt
     8401 gatgaaaagg taaataaaga aagactcata agaatcaatg atagagaaat ggaagaaaaa
     8461 attagggctt tagaaattgg aaaagttaat aactgtgaag aaaatgaaga ggaaagctat
     8521 gtcattaagt ctgatgtaga tgaaaattta atctatggag ataatgcaaa tgctatgatt
     8581 gaaaatatag ttgaattaaa tgcatcttct ggaacagttg cagttgttgg agatatattt
     8641 gatgttgaca ctaaagaact taaaaacgga aaaatactta tgatagcttc aattacagat
     8701 tatactagct caataagctg taaacttttt ttaacagata caaataagga tggagtactt
     8761 gaaaatgtta aaaaaggagc atacttaaaa atcaagggtg acatagttta tgatacatat
     8821 caaagagaaa ttagtatgat gattagtggg ataagaaaag aaactagaat agagagagaa
     8881 gataaatcag aggaaaaaag agtagaactc catgcacata cacaaatgtc ttctatggat
     8941 gctatttgtt ctgttaaaaa gcttgtagag cgtgcagcca aatggggtca ttctgctatt
     9001 gctataacag accatggtgt tgtacaagga tttccagatg ctatgaatgc aggtaagtca
     9061 aataatataa aaatacttta tggagtagaa gggtacctgg ttgaagatga ttctctcatt
     9121 atagaggatg caaatgataa agaactttcg cagacatttg ttgtatttga catagagaca
     9181 actggctttt ctaatacaaa tgataaaata actgagattg gtgctgtaaa aatagaaaac
     9241 tttaagattg tagatagatt tagtgagtta ataaatcctg aaaaagatat ttcttataag
     9301 atacaggaat tgacaggaat aactaatgaa ttaattaaag acaagccaac cattgaagaa
     9361 gttcttccta agtttatgga atttgttgga gatagtgtat tagtagcaca taatgcagag
     9421 tttgatactg gatttatatc gcaaaaatgt agggaacaag gcttgttata taataacaaa
     9481 aaagtagata cacttatgtt agcaagagta atgttgccaa acttaaaaag acatagatta
     9541 aatgtcgttg caaaagaact tggtattcct cttttaaatc accatagagc agtggatgat
     9601 gctgaagcta cagcacttat atttaataag tttttgcaga tgcttacaga aaaaggtgca
     9661 aaaactctaa gtgatgtaaa caatatactt ggaaagattg attacacaaa gcttagcaca
     9721 aatcatataa ccttgatagc aaaaaattct ataggtataa aaaatttata taaaataatt
     9781 tcagatgcac atgtaaatca tttttttaga gcaccaagaa tccttagaag tgtattaaat
     9841 gaatataaag aaggattaat aattggttcg gcttgtgaag ctggggtggt ttttcaagct
     9901 gtaaagaaaa acgtgtctga tgaggaaatg aaaaaaataa tagatttata cgattatatt
     9961 gaagtaatgc ctatagataa taatagattt atgattgata aaggagaagt aaaggacgaa
    10021 gaagagttaa gggagttgaa taggaaacta attgatacag ccaaaaaatt tgacaaaatt
    10081 ccagtagcta ctggggatgt tcatttttta gacaaacatg aagctgtctt aagaaaagtt
    10141 cttaaatatt ctcaaggttt taaagtagat gaagaagaaa cttatttaca ttttagaaca
    10201 acagatgaaa tgttggaaga gtttagttat cttggagaag aattggcata tgaagttgta
    10261 gttgaaaata gtaatctgat tgccgatatg gttgaagata taaaacctat accagatgat
    10321 acttatcctc caattataga gggctcagat gtggagttaa gagaaatgtg ttacaaaaaa
    10381 gccaaacgaa tctatggaga cccaatacca gaaatagttc aaaaaagact ggatagagaa
    10441 ttaaattcaa taataagcaa tgggtatgca gttatgtata ttatagctca aaaactggtt
    10501 gcaaaatctc tttcagatgg atatttagtt ggttcaagag gctcagttgg ctcatctttt
    10561 gcagctacta tgagtgatat aacagaagtt aatcctcttc cagcacatta tatttgtgaa
    10621 aacgaagact gtaaatattc attcttttat gaaataggtg aatggggctc aggtgttgat
    10681 ttaccagaca aggattgtcc aaagtgtgga agaaaacttg ctaaaaacgg tcatgatatt
    10741 ccatttgagg ttttcttagg ttttgaaggt gataaggaac cagatataga cttaaatttc
    10801 tcaggaaatt atcagccaac aattcataaa tacacagaag aactatttgg agaggggtat
    10861 gtatataggg ctgggactat aggtactgta gcagaaaaaa cagcttttgg atacgcaaga
    10921 aaatatgtgg aagaaaataa tataagtgta ccaaatgcag aagtacttag gctttcaaat
    10981 ggatgtactg gagtaaaaag aacctcagga caacatcctg gtggagttat ggttatacca
    11041 gactataaag atgtatacga ttttacacct atacagtatc cagcaaatga tacttcttgt
    11101 ggtgttataa ctactcactt tgattatcat tcaataagtg gtagaatact taaacttgat
    11161 atacttggac acgacggtcc taccattata aggatgcttg aagatatgac tggaataaat
    11221 ataacagaaa ttcctttaga tgataaagag actatgtctc tatttacatc tacagaagca
    11281 ttaggtgtta caccagaaga aataaactgt cctataggtt gccttgctgt accagagttt
    11341 ggaactaagt ttgtacgaca aatgttactt gacacaaaac ctactacatt tgcagaactt
    11401 gtacgtatat ctggtctctc tcatgggaca gatgtttggg taaataatgc acaagactta
    11461 gttagagaag atatagttgg attaaaagat gttatatcta cacgagatga cataatgaac
    11521 tatttaatat ttaaaggatt acctcccaaa atgagcttta caataatgga gagtgtaaga
    11581 aaaggtaaag gtttaaaacc agaacacatt gaagaaatga aaaaaaataa tgttccagaa
    11641 tggtatatag gctcatgtaa aaagattaag tacatgttcc caaaagcaca tgctgttgct
    11701 tatgtaatga catcatttag aattgcatat tgtaaagttc actatccaga agcattttat
    11761 gcgacttatt ttacgacaaa agttgaggat tttgatgcag atttaattgt taaaggatta
    11821 gatgctataa aatcaaaaat aaatgaaatt gagtcactgg gaaatgatgc aaccacaaaa
    11881 gaaaaaggta tgttgaccgt tttagaagtt gctcttgaaa tgtatgctag aggaataaaa
    11941 ttattaccag ttgatatata taaatcagat gcaactgagt ttatagttgt aggagaaaaa
    12001 acattacttc caccaatggc agcaatacaa ggtcttggag gaaatgcggc tataaacatc
    12061 caaaatgaaa gaaaaaatgg tgaatttata tcaaaagaag atttgagaaa gagaacaaaa
    12121 atatcaaaaa cggtaataga aactcttact aatcatggtt cacttgagaa tatgagtgag
    12181 agaaatcaat tgtcattgtt ttaagttagc ccaaaaagtt gcaaataaaa gaattttatg
    12241 atatcatagt atagaaaata gtatactttg cagaaactaa gagtgagaca gctgttctca
    12301 ctcttttatt ttaaatatat tattaaaaag ctggtttatt tttattaaat atattttatt
    12361 taagattata taaactggtc atttacaatt gaataggagg aactttaatg aaaaaaaatt
    12421 tagaagctac aattgaggag attgtaacta aaataacgga tgaacatgga tttgaaatgg
    12481 ttgatgttga atatgtaaaa gaagcaggag aatactactt aagagtatac atagataaag
    12541 aagaaggaat atctttaaat gaatgtgaat tagttagtag agaattaagt ccaatactag
    12601 atgaaaaaga ccctataaaa gaaaattact ttttagaggt atcttctcca gggcttgata
    12661 gagcattaaa aaaagacaga gattttgtta gatatcaagg tagagatgta gatttaaaat
    12721 tatataaacc attaaatgga tgtaagcaat ttgaaggtga acttgtagga ttaacagaag
    12781 ataataatat aaaaatcatt gcaaatggta aggaaatgga atttaataga aaagatgttg
    12841 ctattgtcag attagcaata aagttttagt ggtatattaa atagggagga tataaaaaat
    12901 gaatcatgaa tttatggaag cattagatga attagtagtt gacagaggta tagataaaga
    12961 aatacttata gatactatag aacaagctct tttaactgca tacaagaaaa actttggttc
    13021 agcacaaaat gttagagttg aatttgatag agacaaggga gatataaaag tattttctca
    13081 aagagttgtt gttgatgaat cagatttata tgatactttc ttagaaatag agttagcaga
    13141 tgctagagag ataaatccta attatgaatt aggtgatatt atagaacatg aagttacacc
    13201 taaaaacttt ggaagaattg cagctcaaac agcaaagcaa gtagttgttc aaagaataag
    13261 ggaagctgag agagaaatag tgtataatga atttatagaa aaagaaaatg aaatagttac
    13321 aggagaggtt gctagagcaa ataaaaatgt tgtttatgta aatcttggaa gaatagaagg
    13381 tataatgact caaagtgaac aaataccatt tgagaattat aaagcaggtc aaaaaataaa
    13441 attctatata cttgaagtta aaaagactaa caaaggacct caaatagttg tatcaagaag
    13501 tcatccgggt ctagtaaaga gattgtttga agaagaagtt cctgaaatat atgaaggaat
    13561 agttcaaata aaatctgtag caagagaagc agggtcaaga actaaaatgg cagtaagatc
    13621 tatagatgaa aaaatagacc caattggagc ttgtgttgga ccaaaaggac ttagagtaaa
    13681 aaatatagtg gatgaacttg gcgatgagaa aatagatata ataaaatata gtgaagaccc
    13741 agcagagttt atatcagcag cacttagccc atcaaaggtt gttagagtag atatagatga
    13801 agatgaaaag tctgccttag taatcgttcc agattatcag ttatcgcttg ctataggtaa
    13861 agaaggtcaa aatgcaagac tagcagcaaa attgactaac tggaaaatag atattaagag
    13921 cgaatctcaa gcagaacaag aaatgttaaa tcttgaaaat tccaaagaaa tagaagctga
    13981 ggatgttgaa gctgaattta tcgaccaaga agagttagat acttcagagg ataattttag
    14041 tgaagaagag taaggaggga tgattttgaa aaaagtaaaa aaagtgcctc aaagaaaatg
    14101 catagcatgt caagatagag actctaaaaa agagcttata agaatagtta aaaataaaga
    14161 aggaaaaata tttttagacc caacaggaag agccaatgga agaggagcat atgtatgtaa
    14221 aagctctgaa tgtctaaaaa aagctataaa gagtaaagca ttaaataaag cttttaaaat
    14281 agatgttcct gatgaagtct atgataatct acttatggag ttagaagaat atgaaaaata
    14341 ataaagaaaa agtactttcg ttcttagggc tcgcaactcg tgcagggaaa atagtgtctg
    14401 gtgatgattc aactttgctt gaccttaaaa aaggaaaagt aaatttgatt ttaatcgcag
    14461 aagatgcatc aaataatact aaaaaacttt ttaaagataa atcaactttt agaaatattc
    14521 catatctatt tttttcaaca aaagaggaaa taggatttgc aataggaaaa tctccaagag
    14581 cagttgtagg aataaaagat gaaaattttt ctaaaaagat aattgaacta atagaaattt
    14641 aaaataaaat agggggtgat cttgtgtcaa aaacaagagt ataccaaata gcagaagaat
    14701 taaatatatc aaatgaagag cttataaata agttagctga attagatata aatgtaactg
    14761 acaaagattc agtattagaa ggtgaagagt tagaattagc acttgaaatg ttaggtgaag
    14821 atttatctca agaaaatgga aatgttatag aaatagatgg aaagttgaca gtacaagtat
    14881 tagcaacgaa attagataaa tctccatcag aaataattat gaagcttatg aaaatgggaa
    14941 ctatggcaac aataaatcaa gagataagtt ttgagattgc tgctttggct gccaaagact
    15001 atggatttga attaacagta gctgaaagtg atgatacaga agctttagaa atagaagctt
    15061 taatggaaat tgaagaagac aaagaagagg atttaaaacc tagaccacca gttgttacag
    15121 ttatgggaca tgttgaccat ggtaagacat ctttactaga tgcaataaga aaaactgatg
    15181 tgatctcagg tgaagctgga ggaataactc agcatatagg tgcttcagaa gttaaaatca
    15241 atggacacaa aatagtattt ttagatactc caggacatga ggctttcaca tcaatgagag
    15301 caagaggagc acaagttaca gatatagcaa tattagtagt tgcagcagat gatggtataa
    15361 tgcctcaaac agttgaagct ataaaccatg ctaaagcagc aggtgtacct ttaatagttg
    15421 ctattaataa aatagataaa ccaggtgcaa acccagataa ggttaaacag gaattagcag
    15481 accaaggatt attagttgaa gactggggtg gagaagtaat agcagttcca gtatcagcta
    15541 agaaaaaaga aggaatagat acacttttag aaatggtatt attggttgct gaaatggaag
    15601 agttaagagc taatccaaat aaaagagcag taggaactgt tatagaagct gagcttgata
    15661 aaggaagagg gccagttgca acagtacttg ttcaaggtgg tactttaaca gtaggtgacc
    15721 caatcgttgc aggtgttgca tgtggtaaag ttagagcaat gataaatgca aaaggtaaga
    15781 gagtaaaaac agcaggacca tctacagcag tcgagatatt aggtctatca gaagttccac
    15841 aaggaggaga ccaatttgtc gaagttccaa ctgataagat tgctagaagt gtagcagcaa
    15901 gaagacaaca aatagttaga gatgaaatgt taaaatcaac tcaaagatta tcactagatg
    15961 ctctatttag tcaaatgagt gaaggttcta taaaagacct taatatagtt ataaaagcag
    16021 atgtacaagg ttcagtacag gcagttaaac aatctttaga aaaattatca aatgaagaag
    16081 ttcaagttaa agtaatacat ggtggtgttg gagctgtaac agaatcagac atattacttg
    16141 cagcagcttc taacgcaata ataataggat tcaatgtaag accagttcca ggtgcagaat
    16201 ctctaggaga aaaagaaaat gttgatataa gaacatatac tataatatac aaggcaatag
    16261 aagatataca agcggctatg actggtatgt tagaccctga atatgttgat gaagaaacag
    16321 gaaaagctga aataagagaa atatataaaa tatctggtgt tggaacagta gctggatgtt
    16381 atgtgactaa tggtaagata tttagaaatt gtaaagtaag attagttaga gatagcataa
    16441 taatacatga aggtgagctt gcagcactta agagatttaa agatgatgta aaagaagtta
    16501 attctggata cgaatgtggt atgagttttg taaattataa cgacataaaa gaaggcgata
    16561 tagtagaagc ttatataact aaagaagtag aaagaaaatt ataaattcgt atcaaagaaa
    16621 atcagttagt aaagaaggtc gatggtatgg catcatataa tagaacaaga aggatagcag
    16681 aagaaataag aaaagtcgta agtactatgc ttataaatgg agtaaaagac cctagaataa
    16741 catctatggt gagtgtaact gatgtagaag ttacaaatga cctaagatat gcttatgtat
    16801 atgtaagtat tctaggcgga gatgaagaat ccacactaac aggtcttaaa agtgctggag
    16861 gatatataag aagagaagta ggaaaaaata taaaacttag atatattcct gagatagtat
    16921 ttaaacttga tgattcaata gaaaaaggaa tgtatatgga tagccttata aaaagagtta
    16981 atgaaaaaaa tgctcaacaa aatgaggatg aaaattatga tgaataatat ggatagtatt
    17041 ataaactata tttatgaggg tgactatttt atagttacct ctcatatcag tccagatgga
    17101 gacaatattg gttctacact ttcaatgtat tatacattga agaatttagg aaaaaatgta
    17161 tattatgtac ttgatgatga agctccatta aatttaaggt ttttggttga aggtgtaaaa
    17221 atctataagt ctaatgaatt taatatgaag aactattctc taattgcact tgattgtggg
    17281 gataagatga gaatatgtgt gagtgatgaa atcaaaaata atgcatcaaa attaatctgt
    17341 attgaccatc atgctagtaa tgattcatat ggagatttaa attatgtaga tattgatgca
    17401 tcttctacat gtgaattagt ttataattta ttagttagat ttcagcaaat aaaagatatt
    17461 aatattataa atgaagatat agcaacatgt ttatatacag gtcttgtaac tgatactgga
    17521 aacttttcgt attcaaatgt acatgcaagt agctttgaaa tggcaaaaaa tttacttgtt
    17581 ttaggtgcac aaaaaaatac tataatacaa aatatatatc aaagcaattc ttctggttat
    17641 tacaaattat taggagaagc tctaaagggt ttggagatat ttgattaaaa aatagttacg
    17701 cacactcgtg actttagtca tgagttagta gctaaaatag tcagcatata gggaaactta
    17761 tatgtagaga taggata
//
LOCUS       DAEPHU010000079        17577 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 01A10CD0081
            SAMN05941466-rid12468953.denovo.079, whole genome shotgun sequence.
ACCESSION   DAEPHU010000079 DAEPHU010000000
VERSION     DAEPHU010000079.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941466
            Sequence Read Archive: SRR6291087
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 17577)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17577)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068158.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 22:43:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,892
            CDSs (total)                      :: 3,805
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 87
            rRNAs                             :: 8, 1, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 55
            CDSs (without protein)            :: 55
            Pseudo Genes (ambiguous residues) :: 0 of 55
            Pseudo Genes (frameshifted)       :: 21 of 55
            Pseudo Genes (incomplete)         :: 28 of 55
            Pseudo Genes (internal stop)      :: 16 of 55
            Pseudo Genes (multiple problems)  :: 8 of 55
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17577
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941466-rid12468953.denovo.079"
                     /strain="01A10CD0081"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            <1..237
                     /locus_tag="KR231_003032"
     CDS             <1..237
                     /locus_tag="KR231_003032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453818.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBH0005388.1"
                     /translation="EDKKRFGELQRAIPDCSKKMLVQQLDFLIEQGIIVNQKKLVNNV
                     VESTYFLSESGLRLLPVMEKMIMWSNKNLNCDKY"
     gene            374..1651
                     /locus_tag="KR231_003033"
     CDS             374..1651
                     /locus_tag="KR231_003033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redoxin family protein"
                     /protein_id="HBH0005389.1"
                     /translation="MQNVNLFLVFIEGIVSFFSPCILPILPIYLSILSNSSVENLKEG
                     KTSFIGSSLFKNTIFFALGISTTFFILGSSVKVLSMFFNENKDLIMFIGGIIIIIMGL
                     FYMGIIKSSILNREKRFNVKFKEMKAITAFILGFTFSFGWTPCIGPILASVLVMVSSS
                     SNHLSANLLIAVYTIGFILPFIITAMFYSKLFKTIDKIKSNMEIIKKIGGIILIVSGI
                     LMMVNGFGSISKHFNTSQNSKIESKQEENKRENSTDKEENSDGNDSQKDSNNDNNDKG
                     SNDEDRIKSIDFTLTDQYGKTHKLSDYEGKVVFLNFWATWCPPCKEEMPYIEQLYKDY
                     NKNNDDVVILGVASPNLGREGSREHVVNFLKEQGYTFPVVLDEDGALAYQYGINAFPT
                     TFIIDKEGYVTQYIPGAMDKATMASFIENQRNK"
     gene            1772..3160
                     /locus_tag="KR231_003034"
     CDS             1772..3160
                     /locus_tag="KR231_003034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HBH0005390.1"
                     /translation="MKKTFDAIIIGFGKGGKTLAGDLANRGLKVALIEKSNKMYGGTC
                     VNVACIPTKSLENSANSVKTKNINSWDEVQAEYEKAIDKKETLITKLREANYNKLNSN
                     ENVTIFTGMGTFIDEKTVQVKTENEIYELVADNIFINTGSRPFIPNIKGIENKNIVYD
                     SESLMNLRVLPKKMTIIGAGFIGLEFAGIYSSFGAEVTILNSNNGILPNEDVEDSEEI
                     IKLLAKRNVKIVNNANIKEIKEVSELAIVEYEVDGKSKELTSNMILVATGRKANTEGL
                     GLENAGIELNERGFIKVSETLKTNKEHIWAIGDINGGPQFTYISLDDYRIVINQLFGD
                     KTRTTNDRKNIPNSIFISPAFSRVGLNVKQAKEKGYEVLVAKMPVEAIPRAKQIGKAD
                     GFIKIVIDKKSNKILGASMICENSSEIIHLIQLAVDLEVEYTYLRDRVYAHPTMTEAL
                     NDILSPNMIKEV"
     gene            3364..4077
                     /locus_tag="KR231_003035"
     CDS             3364..4077
                     /locus_tag="KR231_003035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017208807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF434 domain-containing protein"
                     /protein_id="HBH0005391.1"
                     /translation="MNKISKRGFDDSDKRWFSSKELTRLIKAKEEIEWLLNRDYKIDP
                     VVTFVGDRYQFSIRQRDALKRAVCTDEKNIIRQSKRLSLDKIKEDTVNIDGFNLIISI
                     EVGLSGGTLVIGSDGNIRDLAGLRGTYKIIDKTEEALNLIGKFFNKYNAQNLKFYLDA
                     PVSNSGNLKYRILEHAKTWGIETEVELVKNADVVLEKLDRVVSSDAVIVDKCISYFNV
                     ARGIIEEYIKECNIINLNK"
     gene            4195..5064
                     /locus_tag="KR231_003036"
     CDS             4195..5064
                     /locus_tag="KR231_003036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SH3 domain-containing protein"
                     /protein_id="HBH0005392.1"
                     /translation="MRGWICVKLTKLNIKKYRAPIYKYALANINLRSAKSTNSSIITV
                     IPQGAKMEVLDEEDDWIKVMYNSQEGYVYKELVSVSEYAWSNLNLREDKSTTSNIITV
                     IPEKSRVEVLQVDGDWSKVVYDDKIGYVFNYFLSIDGNKPNELDYKYFYTDMIKFVNE
                     NNIKSTSDYLIVTDLRNKYTYIFKKDNGGWGQLYKWQCTIGKPETPTITGIFYISGRK
                     PSFGTDEYSVKYATRIKGGYYYHSVLYDSTGSYIIDGRLGEALSHGCIRLSTENAKWI
                     YDNIPDTTTVIIH"
     gene            complement(5219..6364)
                     /locus_tag="KR231_003037"
     CDS             complement(5219..6364)
                     /locus_tag="KR231_003037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase"
                     /protein_id="HBH0005393.1"
                     /translation="MSIYYVPPINLLGKGCLNEAKDSIKSLGTKKAFIVSDKFLVSNG
                     TVKKVTDILSQIDIDFVVYDEVKQNPTVTNVNKGLKILKSENCDFVITIGGGSPQDCG
                     KAISILATNGGDIRDYEGINKTSKKCLPIIAITTTAGTSAEVTINYVITDEDRHVKMI
                     MVDTNSLATMTVNDPELMISKPSNLTAATGMDALTHAIEAVVANGAYDVTDSTALYAI
                     KQIFKYLPRAVKNGNDIEAREQMCYACFLNGIAFSNAGLGNVHAMAHQLGGLYDLPHG
                     VCNAMLLPIVEEENAKSAPAKFRPIAEVIGMDVNNKSDKECVDFVIDKIKALSEEVGI
                     PKSLKDVGVDNPNFELLAENSMKDACAGANPVFFDKDKIIELFMKIS"
     gene            complement(6697..7473)
                     /locus_tag="KR231_003038"
     CDS             complement(6697..7473)
                     /locus_tag="KR231_003038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IclR family transcriptional regulator"
                     /protein_id="HBH0005394.1"
                     /translation="MTSDNHRPTARILDILEALAESENGYTLTEIADVINAPKSSIFP
                     IVHTLNARKYITIDKNTSKYSIGIRSYTLGSSFFEKRTIFNYIIDEMTNIVNSCSETC
                     QLGILDNNEVLYIGKVDSPEPIRLISYVGKKIPANCTGLGKALLCDFDKEKLISLYPD
                     GLKGFTEKSITDFDVLYDQLLEVQRTQIASECEESMEHLKCLAVPIRKNGCIRAAVSV
                     TLPLFRANDEKIELIKKLLLNAQKNIQSMMEERNEDIVIN"
     gene            8055..9029
                     /locus_tag="KR231_003039"
     CDS             8055..9029
                     /locus_tag="KR231_003039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-keto-3-deoxygluconate permease"
                     /protein_id="HBH0005395.1"
                     /translation="MIMDFIKKIPAGMMIVPMFIAAFINTFCPDIVQIGSFTTAVFSS
                     VGSATIIGVQLVCLGTQLQFREMPKVLKRGGILLGSKFAIGALIGILIGKLFGMDGVL
                     GLTTLAVISAVTNSNGSIYLSLMTSYGDETDCATMSLLTLNDGPFFTLIALGTSGLAN
                     VPLLSLLAAIVPILVGMIIGNFDKKMKEFLEPGCNLLVPFVGFALGSSINLASILKGG
                     LSGVLLGLISVFVGGIFIVFCDKFIGKRPGYAGWAVATTAGNAIAVPAAVALVDPSWQ
                     PYVATATTQVAAAVVVTAILVPLITSWWAKKYGCPKFPKQNEDGTITA"
     gene            9127..9432
                     /locus_tag="KR231_003040"
     CDS             9127..9432
                     /locus_tag="KR231_003040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UxaA family hydrolase"
                     /protein_id="HBH0005396.1"
                     /translation="MINAVIIDEKDNVAVAIEAIAKGSEISFKLKDKTVKTITALDDI
                     TIYHKLAIKDMAKGDKVTKYGEHIGEANQEIKSGQHVHIHNVRSVREDLDKQVMTNI"
     gene            9588..10748
                     /locus_tag="KR231_003041"
     CDS             9588..10748
                     /locus_tag="KR231_003041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UxaA family hydrolase"
                     /protein_id="HBH0005397.1"
                     /translation="MKFYGYKRPDGRVGIRNHILILPTSVCASDTTRIIASQVQGAVT
                     FNNQNGCSQVHSDQQLTMDVMAGYAANPNVYGVIVVSLGCENCQNDLVVDAIKERTNK
                     PIKTLVIQEEHGTLKTIEKAVRYAREMAQEASLLRKEEFPISELILGTECGGSDPTSG
                     LAANPLIGELSDKLVDLGATSILSETTEFIGAEHILARRAVNEEVKEKILHIVHRYEN
                     SLKLVGEEVREGNPSPGNIAGGLTSLEEKSLGCIHKGGHRQISEVYDYAKQIDKKGLV
                     IMDTPGNDASSVAGMVAGGAQIVVFSTGRGTPSGNPIAPVIKITGNKITFANMEDNMD
                     FDASPVIYGPQTMEELTDDLLNMVVDVANGKQSKAESLGYTEMAIARVCNYV"
     gene            10798..11700
                     /locus_tag="KR231_003042"
     CDS             10798..11700
                     /locus_tag="KR231_003042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fumarylacetoacetate hydrolase family protein"
                     /protein_id="HBH0005398.1"
                     /translation="MKFVSFTEGENECKRTGVFSKDELFIIDVNSLNLSRNFKDLNEL
                     IQNVSSEDIIKLKTIINESTFYNYDVFKRERCTVHVPIEKPIHDILCVGVNYKDHLEE
                     TQTHFDDSFEEPQKTVYFTKRVTKAIGPEDEIDGHFEINNQLDYEVELGVVIGKTGVN
                     IRKEEVEDYIFGYTVINDISARKLQKEHVQWFRGKGLDTFTSLGPCILHKSAVPFPIK
                     LKVCSRVNGEERQSSNTGLFISDVSDIVSELSKGMTLEAGDIIATGTPSGVGMGFSPP
                     RYMSSGDVVECEIESIGILKNYIK"
     gene            11780..12673
                     /locus_tag="KR231_003043"
     CDS             11780..12673
                     /locus_tag="KR231_003043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrodipicolinate synthase family protein"
                     /protein_id="HBH0005399.1"
                     /translation="MKAEFLTPVVTIFDEEGNLDKEGNKKVYDHLIDGGVDGLVIMGS
                     TGEFFNMSMDMQKELIDLVTSHVNKRVKVFIGTSRMCINESIELSNYAHNSGADGVMI
                     ISPYYFSLDDDSIELFYSEIAKNTEAEIYLYNYPDRTGYDLSPELTLRLARKHKNIVG
                     YKDTVTLMGHTRDLINTMKIEFPEFKVYSGYDENFIHNLMSGGAGCIGGLSNLIPEVC
                     SKWAEAYNNRDMEKVIEIQKYINKAMDFYLITNPFIPAMKKAMNIRGLQISDYMTAPF
                     VKPNEKQVCEIKKLMNELNIC"
     regulatory      12726..12907
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00174"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="cobalamin riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="adenosylcobalamin"
                     /db_xref="RFAM:RF00174"
     gene            13135..14265
                     /locus_tag="KR231_003044"
     CDS             13135..14265
                     /locus_tag="KR231_003044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HBH0005400.1"
                     /translation="MKFKSNVLKQFFLIAMVIFMVGGLIGCSKSDKENKQASTGKKLE
                     LKYASGFSVEDLEDGIKKVTDGDNRELILIPKKIKIPEKYKNANIVRTPVDNVLIAST
                     TQACSLRTIDELDSIKAVTTEEQYWTIKEIKDLMKDGKIHYVGSNLAPDYEKIVDLNP
                     DLTIVSSGLSEADTKFIDKLKELGLNYVVDNEYKEQNPFGRMEWTSLIAAFYDKEDMA
                     TSELNKTVQKVEEVSKKIKNKAKPKVVWASVYEGSAYIAPKDSYVDNMIKMAGGINAC
                     ASIDSNEGRVSIEQLHEVAKDADIFVYSSSSDYAPNLDSIKSSAPVLADLDVVKNGNL
                     WVFAPDYYQSVDKTDELIVDLVEMFHPGTTGEKIKHYINYDK"
     gene            14337..15362
                     /locus_tag="KR231_003045"
     CDS             14337..15362
                     /locus_tag="KR231_003045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HBH0005401.1"
                     /translation="MDFINKMRIRNTTIFIVLIISMILTFLVCVAFGSVKIEFKEVID
                     VVLRGMDNTEHYKIIYNIRIPRVLATMVGGACLAVSGILLQIFFKNPIVEPYILGVSS
                     GSTLSVALMILGGYTLGFESVNSMSIFVAAFIGALIVMSIVILFANKVKNITTLLIIG
                     IMTGYVCSGITNVLQSFANSDKLKEFTMWSMGSFSGFTWEKVEILIIVGILGLLMTVF
                     IIKPLNAFLLGEEYAKSIGINIRFFRVLIVFISSILAAIVSAFAGPIGFIGLAVPQIS
                     KMIFKTSDNRVLIPVVIFLGSIVTALCDLISRVILSPVELPISTITSLLGAPIVVMLL
                     VKRKDRA"
     gene            15365..16561
                     /locus_tag="KR231_003046"
     CDS             15365..16561
                     /locus_tag="KR231_003046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH0005402.1"
                     /translation="MLKTNNLSVGYNNKVVISNINVEVKNGEILCLLGSNGAGKTTLL
                     RSLSKLISPIKGEIYLNGVNINCISRKALSKKMALVLTNRLLGDLMTVQDIVNIGRYP
                     YTGFFGSLSKKDLIMVDEALESVDALHLKKRYFDELSDGEKQKVLVARALVQEPEIII
                     LDEPTTHLDIKHRLELINILKKLSKEKSISVILSLHEIDIALKSCDKVALIKNNKVIA
                     YGQPEDVVDEDIINSLYELDDKNFNSLLGSVEISNKSKNEVFIIGGGGKATPIYRAFT
                     KKGIGLYSGIIHENDIDYEIGRTMGIKMFTENPFEPISDESFNLAIRNLNDSKIIIDT
                     GFSVGETNKRNIDIIKEALKLDKKVYSFRNRDESKKYYDSLDSKIEHIDKVSQIINSA
                     DINNLL"
     gene            complement(16689..17414)
                     /locus_tag="KR231_003047"
     CDS             complement(16689..17414)
                     /locus_tag="KR231_003047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pentapeptide repeat-containing protein"
                     /protein_id="HBH0005403.1"
                     /translation="MKTISKQELEKTLEKHYLWLKNNNAGEKADLKELRLENMDLRGY
                     CLSNIDFSWSDLINLNLEKADLENSIFNNSYLSDCSLKNSILKNADLSGASFRFCDLS
                     NSDIRGANLENSNLEHATLNGVISDESTRFFKLYCPETGAFIGYKKCFNFRMVQLLIP
                     SDAKRVSATSNACRCDKAKVLSITSIDGKESFKSARAYADENFIYRVGETIVAEDFNE
                     NRWKESTTGIHFFLTREEAIGYL"
BASE COUNT         6730 a         1971 c         3066 g         5810 t
ORIGIN      
        1 gaagataaaa aacgatttgg agagctacaa agagctatac cagactgtag taagaaaatg
       61 ttagttcaac aactagattt tttaattgaa caggggatta tagtcaacca aaaaaagttg
      121 gttaataatg ttgtagagtc aacatatttt ttaagtgaat caggattacg attgcttcct
      181 gtcatggaaa aaatgattat gtggagcaat aaaaatttaa attgtgataa atactaaaat
      241 ttactctgta agtaatgaaa atttaattaa gctatgagta gaaaaatgta ttaaaattac
      301 ataatttttt agttagattt taatttagaa atgggattgt aatattggaa ataaaataag
      361 gaggaatttt aatttgcaaa atgtaaattt atttttagta tttatagaag gtatagtatc
      421 attcttttca ccatgtatac tgccaatttt gcctatttat ttgagtatat tgtcaaatag
      481 tagtgtagaa aatttaaaag aaggaaagac gagttttata ggaagttctt tatttaaaaa
      541 tactatattt tttgctcttg gaatctcaac aacattcttt atattgggtt catcagtaaa
      601 agtattgagt atgtttttta atgaaaataa agatttaata atgtttattg gtgggattat
      661 aattattatc atgggattat tttacatggg aataattaaa tcttcaatat tgaatagaga
      721 aaaaagattt aatgttaagt ttaaagaaat gaaagcaata acagctttta tattaggttt
      781 tacgtttagt tttggatgga caccttgtat tggtccaata ttggcatctg tattagtcat
      841 ggtttcaagt tcaagtaatc atcttagtgc caatctttta atagcagtat atactattgg
      901 ttttattttg ccattcataa ttacagctat gttttacagt aaactattta aaactataga
      961 taagataaaa tctaacatgg aaattattaa aaaaataggt gggattatac ttatagtatc
     1021 aggaatatta atgatggtaa atggatttgg aagtataagc aaacacttta atacgtcaca
     1081 aaatagtaaa attgaaagca agcaagaaga aaataagcga gaaaattcta ctgataaaga
     1141 agaaaattct gatggtaatg atagtcaaaa agactctaat aatgacaata atgataaagg
     1201 gtctaatgat gaagatagaa taaagtctat tgattttact ttaacagacc agtatggtaa
     1261 aacacataaa ttaagtgatt atgaaggcaa agttgtattc ttaaatttct gggctacatg
     1321 gtgtcctcca tgtaaagaag aaatgcctta tatagaacaa ctgtataaag actataataa
     1381 aaataatgat gatgtagtaa ttttaggagt agcttcacct aatttaggta gagaaggttc
     1441 aagggaacat gtagttaact tcttaaaaga acaaggttat acattccctg ttgtacttga
     1501 tgaagatgga gcattagcat atcaatatgg aattaatgct tttccaacta catttataat
     1561 tgacaaggaa ggatatgtaa ctcagtatat tccaggagct atggataagg caactatggc
     1621 atcatttatt gaaaatcaga gaaataaata aaagtattta agtataagtt tataaatcaa
     1681 tttaaggtta caaaaaagtg cctaattgta ccacctaaat aatcttgtta tagtaaaagt
     1741 ataaacaata caagaaaggg ttgaatttta tatgaaaaaa acatttgatg ctataataat
     1801 aggatttgga aaaggtggaa aaacattagc aggggatttg gcaaacaggg gattaaaagt
     1861 agctttaata gaaaagtcaa acaagatgta tggtggaaca tgtgtaaatg tggcatgtat
     1921 accaacaaaa agcttagaaa attcagcaaa cagcgtaaaa acaaagaata taaattcttg
     1981 ggatgaagta caagctgaat atgagaaagc tatagataaa aaagaaactt taattacaaa
     2041 actcagagaa gctaactata ataaattaaa ttcaaatgag aatgtaacta tattcacagg
     2101 aatgggaact ttcattgatg aaaaaacagt tcaagtcaaa actgaaaatg aaatttatga
     2161 gttagtagca gataatatat ttattaatac tggttcaaga ccatttatac ctaatattaa
     2221 gggaattgaa aataagaata tagtatatga tagtgagtct cttatgaatc taagagtttt
     2281 acctaaaaaa atgacaatta taggagctgg atttataggt ttagaatttg ctggtattta
     2341 tagttcattt ggagcagaag ttacaatatt aaactctaat aatggcattt taccaaatga
     2401 agatgttgag gattcagaag aaataataaa attacttgca aagagaaatg taaaaattgt
     2461 taataatgca aatataaaag agattaaaga agtttctgaa ttagcaatag tagaatatga
     2521 agtagatggt aaatctaaag aattaacaag taatatgata cttgtagcta caggaagaaa
     2581 agcaaacact gaagggctag ggctagaaaa tgcaggtata gaattaaatg aaagaggatt
     2641 tattaaagtc tcagaaactc ttaagactaa taaagagcat atatgggcta taggagatat
     2701 aaatggaggt ccacaattta cttatatttc attggatgat tatcgcatag ttattaatca
     2761 gttatttgga gataagacta gaacaactaa tgatagaaag aatatcccaa attctatatt
     2821 tataagtcca gcattttcaa gagttggtct taatgttaag caagctaaag aaaagggata
     2881 tgaagtatta gtggcaaaga tgccagtaga agcaattcca agagctaaac agattggcaa
     2941 ggcagatggg tttataaaaa tagtgataga taaaaaatcc aataagatac ttggagctag
     3001 tatgatatgt gaaaattcaa gtgagattat ccatcttatt caattagctg tagatttaga
     3061 agtagagtat acatatttaa gagaccgtgt ttatgcacat ccaactatga cagaagctct
     3121 taatgatatt ctatctccta atatgataaa agaagtataa cataagttta atatataaat
     3181 ctaaaattat cattataagt agattttaga aagaggctat ctcaaaaaat agagataagt
     3241 ctctttttta ctgtttaaat aataaaaata tattttaatg gtattaaaaa ttatcttaaa
     3301 aggtgaaata atctgtattt aatgtagtac agttatatct ttaaagcaag gtggtgaaat
     3361 gatataaata agatatctaa aagagggttt gatgatagtg ataaaagatg gttttcaagt
     3421 aaagaattaa caagacttat aaaggctaaa gaagaaatag aatggttatt aaatagggat
     3481 tacaaaatag acccagtcgt tacttttgtt ggtgatagat atcagttttc tataagacaa
     3541 agagatgcat taaaaagggc agtctgtact gatgaaaaaa atattataag acaatcaaag
     3601 aggctttctc tagataaaat caaagaagat accgtaaata tagatggctt taatttgata
     3661 atatccatag aggtaggatt atctggtggt actctagtaa taggaagtga tggcaatata
     3721 agagatttag caggtcttag gggaacctat aagattatag ataaaacaga agaagctttg
     3781 aatctgatag gtaaattttt taataaatac aatgcacaga atcttaaatt ttatttagat
     3841 gctccagttt ctaattcagg aaatttaaag tataggatat tagagcatgc caaaacttgg
     3901 ggaattgaaa ctgaagtaga attagtaaaa aatgcagatg ttgtattgga aaaattagat
     3961 agagtagtta gtagtgatgc agtcatagtt gacaagtgta taagttattt taatgtggct
     4021 agaggtataa ttgaagagta tattaaagaa tgtaatatca taaatttaaa taaatagata
     4081 aatataggtg agaatatata agtatatgta gcaatattct tagtaataca agtaaagttt
     4141 gaaaatagga gaacgaatac atatcgaatt tcataaaatg ttgtaaaaag acatatgaga
     4201 ggatggatat gtgtgaaatt aactaaacta aatattaaaa aatatagagc acctatatat
     4261 aaatatgctt tagcaaatat aaatttgagg tctgctaaat ctaccaattc aagtatcata
     4321 acagtaatac ctcagggagc caaaatggaa gtattggatg aggaagatga ctggattaag
     4381 gtgatgtaca attctcaaga aggatatgtg tataaggagt tggtatcagt aagcgaatat
     4441 gcttggagta acttaaactt aagagaagat aaatctacaa cttccaatat aattacagta
     4501 attcctgaaa aatctagggt tgaagtcctt caagtagatg gagattggag taaggttgta
     4561 tatgatgata aaataggata tgtttttaat tattttttat caattgatgg gaataaacca
     4621 aatgaattag attataagta tttttatact gacatgatta aatttgttaa cgaaaataat
     4681 attaaaagta ctagcgatta tctaattgta acagacctta gaaataaata tacttatatt
     4741 tttaagaaag ataatggagg atggggacaa ctttacaagt ggcaatgtac tataggcaag
     4801 cctgagactc caactataac aggtatattt tatataagtg gaagaaaacc ttcttttgga
     4861 acggatgagt attcagttaa gtatgctact agaattaaag gtggatatta ctatcattct
     4921 gtactatatg attcaacagg aagttatata atagatggca gacttggtga agctcttagt
     4981 catggatgta taagattaag tacggaaaat gcaaagtgga tatatgataa tataccagat
     5041 acaacaacag ttataattca ttaagaaaaa ttttgagttt tttattggga taatgattct
     5101 taaattaata ggattatata ttaacttctc ataaagagta ctatttaaaa agtgtaataa
     5161 gagagtgcta ttaacaaaac aaagatattt tgaggcactc tcttataaat atacataatt
     5221 aagatatttt cataaacaat tctataatct tatctttatc aaagaaaaca ggattagcac
     5281 cagcacaagc atctttcata gagttttctg caagcaattc aaaattagga ttatcaacac
     5341 ctacatcttt taaagatttt gggattccaa cctcttcaga aagagctttt atcttatcta
     5401 ttacaaagtc aacacactct ttatctgatt tattatttac atccattcca ataacttcag
     5461 ctattggtcg gaatttggca ggggctgatt tagcattttc ctcctcaact attggaagta
     5521 gcatggcatt acatactcca tgaggtaaat catataaacc tcctaattga tgagccatag
     5581 catgtacatt tccaagacct gcattactaa aggcaattcc atttaaaaaa caagcataac
     5641 acatttgttc tctagcttct atgtcattac catttttaac agctcttgga aggtatttaa
     5701 atatctgctt tatagcatat aaggcagttg aatctgtaac atcataagca ccattagcta
     5761 ctacagcttc tatagcatga gttagtgcat ccataccagt tgctgctgtt aaattagatg
     5821 gtttgctaat cattaattct gggtcattta ctgtcattgt ggctagtgaa ttggtatcaa
     5881 ccattatcat ctttacatgt ctgtcttcat cagttataac atagtttatt gtaacttcag
     5941 cagatgtacc agcagtagta gttatagcta tgataggaag acatttttta gaagttttgt
     6001 tgataccttc atagtctcta atatctcctc cattagtggc taatatagag atagctttac
     6061 cacagtcttg tggagaacca cctcctatag ttataacgaa gtcgcaattt tctgatttta
     6121 atattttaag tcctttattc acattagtta cagttggatt ttgtttaact tcatcataaa
     6181 caacaaagtc tatatctatc tgagataaaa tatctgttac tttttttaca gtaccatttg
     6241 aaactagaaa tttatcacta acaataaatg cttttttagt tcctaatgat ttaattgaat
     6301 ctttagcttc attaagacat cctttcccaa gtaaatttat tggtggtaca taataaatgc
     6361 tcataactaa aatctccttt tattttcatt gatttttatg taaaaatata tatctaacaa
     6421 ttttcactaa tttactcata atatatcgta tcttagattg agatagggtt gctggttctt
     6481 atataagaac ttaattcgta attacgatta tgattagaat ttaacatagt atttttatca
     6541 tgtcaataaa aatataaaaa atattataaa aaaaacaaag ttactgtagt taaatcagca
     6601 actttgtttt tatagtataa atcaaataaa tacattagtt taaaacaaaa tttttaatta
     6661 ttatgttttg atatcttcca tatacagaat attaatctaa tttattacaa tgtcttcatt
     6721 acgttcttcc atcattgatt gaatattttt ctgagcattt aagagtaatt tttttatcag
     6781 ttctattttt tcgtcattag ctctaaataa aggcagtgtt acactaacag cagctcttat
     6841 acatccattt tttcttattg gtacggcaag acattttagg tgttccattg attcctcaca
     6901 ctctgaagct atttgtgttc tttgaacttc aagaagctgg tcgtataaaa catcaaaatc
     6961 tgtaattgat ttttctgtaa aaccttttag accatctgga tataagctta ttagtttttc
     7021 cttgtcaaaa tcacataaaa gagcttttcc aagacctgta caattagcag gtattttttt
     7081 tccaacataa gaaataagtc taatcggttc tggagaatct acttttccaa tataaagaac
     7141 ttcattattg tcaagtatac caagctgaca agtttcagaa caggaattaa ctatattagt
     7201 catttcgtca attatatagt taaaaatagt tcttttttca aaaaatgaag accctaatgt
     7261 gtaagaacgt atccctatag aatatttgga tgtgttttta tcaatagtaa tgtattttct
     7321 agcattaagt gtatgaacta taggaaagat gctacttttt ggagcattga taacatctgc
     7381 tatttctgta agagtatatc cattttcgga ttctgctaat gcttctaaaa tatctaatat
     7441 cctagctgtt gggcgatgat tatctgaagt cataaatttc cccctctttt tattaattta
     7501 aagtattaga atatgttgat tttagcacac tatacgatat tttacaatgt agaaaataaa
     7561 tatgtaaatt tatatataaa taagctcttg atttagatac agatagatat ttttttagac
     7621 tgtacattaa ggaataacta atttccaaaa tatacctaaa gaaagtaagt gatatttagt
     7681 tatataattt aagtaaatat atgcaatagt tatttttata tgtaaatatc aaaatattat
     7741 gaacttatat tttatctatt ttttacactg tataaaaact ttatagtttt gaatactata
     7801 taattttaaa tacgctgtat ttttgcatat aaggaagtca tttgataata tacaaggtat
     7861 tatcagaaag tttgaaaaaa ttttgacaaa aatttatttt ttttattgac tcataaatag
     7921 gaaaatgcta tcattaattc aaagattcgt aattaaaaac ttagttcttg aatacgaacc
     7981 gaaacggccg ttagaattaa agctaaaaac ttaataagag taattaaata tcatgtttta
     8041 ggaggattaa ctttatgata atggatttta ttaaaaaaat tcctgcaggt atgatgatag
     8101 tgccaatgtt tatagcagct ttcattaata ccttttgccc agatattgta caaataggtt
     8161 cgtttacgac agcagtattt tcaagtgttg ggtctgcaac tataattggg gttcaactgg
     8221 tatgcttggg aactcagctt caatttagag aaatgccaaa agttttaaag agaggtggta
     8281 tacttcttgg ttctaaattt gctataggtg ctttgatagg tatacttata ggaaagctat
     8341 ttggaatgga tggtgtcctt ggtctgacaa cattggctgt tataagtgca gttacaaata
     8401 gtaatggtag tatatatctt tcattgatga cttcatatgg agatgaaaca gattgtgcaa
     8461 ctatgagttt acttacttta aatgatggac cattttttac attaatagct cttgggactt
     8521 caggtcttgc aaatgtacca ttgttgtcat tattggctgc aatagtgcca atacttgttg
     8581 gtatgataat aggaaatttt gacaaaaaaa tgaaagagtt tttagagcca gggtgtaatt
     8641 tactcgtacc ttttgtaggg tttgcacttg gtagtagcat aaatcttgca agtatactaa
     8701 aaggaggttt atcaggagta ttacttggat taatatctgt atttgtagga ggtatattta
     8761 tagtattctg tgataaattt ataggaaaac gtccaggata tgcaggatgg gctgtagcta
     8821 caactgctgg aaatgcaatt gctgtacctg ctgctgttgc attagttgac ccatcatggc
     8881 aaccatatgt tgcaacagct acaacacaag tggcagccgc agtagttgtc actgcaatat
     8941 tagtacctct tataactagt tggtgggcta agaagtatgg atgtcctaag ttcccaaaac
     9001 aaaatgagga tggtacaata acagcttaat ttatattaca gtgagttgtt ggtaaaataa
     9061 taaattcttt aattagattt taggatatta ataaaattat attatttata aaggagagca
     9121 agaataatga taaatgcagt gataattgat gaaaaagata atgttgcagt agctattgaa
     9181 gcaatagcta aaggtagtga aattagtttt aaattaaaag acaaaacagt aaaaacgatt
     9241 acagcactag atgatataac tatttatcat aaattggcta taaaagatat ggccaaaggt
     9301 gataaagtta ctaaatatgg tgaacatata ggagaagcaa atcaggaaat aaaaagtggc
     9361 caacatgtac atattcataa tgttagaagt gttagagagg atttggataa acaagttatg
     9421 actaatatat aaaataatat ttatagagtt ataaaagttg tattcattgc ttttagtgtc
     9481 aaatagtttt taaataggtt tttagctgtt tgattagtga gtgtaataaa aattataata
     9541 tataaaaatt atagaaagta tatagactat tttaggagga aatcagtatg aaattttatg
     9601 gatataaaag accagatgga agagttggta taagaaacca catattaata ttgcctacga
     9661 gtgtgtgtgc atcagataca actagaataa tagcatcaca agttcaaggg gcagttacct
     9721 ttaataatca gaatggatgt tcacaagtac attcagacca acaattaact atggatgtta
     9781 tggctggtta tgcagcaaat ccaaatgtat atggtgtaat agttgtatct ttgggatgcg
     9841 aaaattgcca aaatgatttg gtagttgatg caataaaaga gagaacaaat aagccaataa
     9901 aaactcttgt aatacaagaa gaacatggaa ctttaaaaac tatagaaaaa gctgttcgtt
     9961 atgctagaga aatggcacaa gaagcttctt tgcttagaaa agaagaattt ccaatatctg
    10021 aacttatact aggaactgaa tgtggtgggt ctgacccaac aagtggatta gcagcaaatc
    10081 cattaatagg tgaattaagt gataaacttg tcgatttagg agcaacatca attttaagtg
    10141 aaactactga atttataggt gcagagcata tactagctag gagagcagta aatgaagaag
    10201 taaaagaaaa aatattacat atagtacata gatatgaaaa ttcattaaaa ttggttggag
    10261 aagaagttag agaaggtaat ccatctcctg gaaatatagc tggtggttta acaagtttag
    10321 aagaaaaatc acttggttgt atacataaag gtggtcatag acaaataagt gaagtatatg
    10381 attatgccaa acaaattgat aagaaaggtc ttgttataat ggatacccct ggaaatgatg
    10441 cttcatctgt tgctggtatg gtagcaggag gagcacaaat agtggtattt agtacaggaa
    10501 gaggaacacc atcaggaaat ccaatagcac cagtaataaa aataactgga aataaaataa
    10561 cttttgcaaa tatggaagat aatatggatt ttgatgctag tccagttatc tatggtccac
    10621 aaacaatgga agaattaaca gatgatttgt taaatatggt tgtagatgta gcaaatggaa
    10681 aacaatcaaa agcagagtcc cttggatata ctgaaatggc aatagctaga gtatgcaact
    10741 atgtataatc tttaagtaag aaaataaata catagaattt taataaaggg tgagattatg
    10801 aagtttgtaa gttttactga aggagaaaat gaatgtaaaa gaactggagt tttttctaaa
    10861 gatgaattat ttattataga tgttaactct ttaaatctca gtagaaattt taaggattta
    10921 aatgaattaa ttcaaaatgt atctagtgaa gatattatta agttgaaaac tattataaat
    10981 gaaagtacat tctataatta tgatgttttt aaaagagaga gatgtacggt acatgttcct
    11041 atagaaaaac caatacatga tatcttatgt gtgggagtga actataaaga ccatcttgaa
    11101 gaaactcaaa ctcactttga tgatagtttt gaagaaccac aaaaaacggt ttattttaca
    11161 aaacgtgtga caaaggcaat aggtccagaa gatgagatag atggtcattt tgagataaat
    11221 aatcaactag actatgaagt tgaacttgga gtagtaatag gtaaaacagg tgttaatatt
    11281 agaaaagaag aggtagaaga ttatatcttt ggttacactg ttataaatga tatttctgct
    11341 agaaagttgc aaaaagaaca tgttcaatgg tttagaggaa aaggattaga tacatttacc
    11401 tctttaggtc catgtatttt acataaaagt gcagttcctt ttcctataaa acttaaagta
    11461 tgtagtaggg taaatggtga agaaagacaa agttctaata caggattatt catatcagac
    11521 gtttcagaca tagtttcaga actttcaaaa ggtatgacct tagaggctgg agacattata
    11581 gctactggaa caccttctgg agtagggatg ggattttcac ctcctcgata tatgagtagt
    11641 ggagatgtag ttgaatgtga gattgagagt attggaattt taaaaaatta cattaagtaa
    11701 ctgttttaat ataattaata ttaaagctaa atctgatgta ttaatgaaca tattaaaata
    11761 aattttagga gtttaaatta tgaaagcaga atttttgaca ccagttgtta caatatttga
    11821 tgaagaagga aatttagata aagaaggtaa taaaaaagtg tatgaccatc ttatagatgg
    11881 aggtgtagat ggactagtca taatgggaag tactggagag ttctttaata tgtctatgga
    11941 tatgcaaaaa gaacttatag atttagtaac tagtcatgta aataagagag taaaagtgtt
    12001 tataggtaca agtcgtatgt gtataaatga atctatagaa ctttcaaact atgcacataa
    12061 tagtggagca gatggtgtta tgataataag cccttattat ttctctcttg atgatgatag
    12121 tattgagtta ttttatagtg aaatagctaa gaatacagag gctgaaatat atttgtacaa
    12181 ttatccagat agaactggtt atgatttaag tccagaactt acattaagac ttgcaagaaa
    12241 acataaaaac atagttggat ataaggatac agtaactttg atgggacata ccagagattt
    12301 aataaatact atgaaaatag agttcccaga atttaaggtt tatagtggtt atgatgaaaa
    12361 ctttatacat aatctaatgt ctgggggagc aggttgtata ggggggttat caaatttaat
    12421 tccagaagtt tgctccaaat gggctgaagc ttacaataat agagatatgg agaaggttat
    12481 agaaattcaa aaatatatta ataaagcaat ggatttttac ttaataacca atccatttat
    12541 accagcaatg aaaaaagcta tgaatatcag agggttacaa ataagtgatt atatgactgc
    12601 tccatttgta aaaccaaatg aaaaacaagt atgtgaaatt aaaaaattga tgaatgaatt
    12661 aaatatatgt taaatcaacc ttgcaaagag gtcaacaata aattacaatt atcttaataa
    12721 aaattaaatt aaaataatac tagggtacta tattagttta atagggaaag tgatgaaaat
    12781 tcactacagc ccccgctact gtatacggat acgaaatcaa aatccactga aatttataaa
    12841 aattttggga agggtgatgg aggaaaagcc gtgagtcagg agacctgccc agtattatat
    12901 aagttcaatt tagggtggag attgtaattt ataataaaat gaagtatcaa ttcgtttttg
    12961 taaagttgat atatgaactt ctccttatta aattaggaga agttttttat tttattaaaa
    13021 ggttatactt attaaagatg actttaggat aactttaata agtatacttt aaaaagcata
    13081 tattattaaa gttttttagc cactcataaa aaataagata ttggagtgaa agagatgaaa
    13141 tttaaatcaa atgttttaaa gcagtttttt ttaattgcta tggtaatttt tatggtagga
    13201 ggtcttatag ggtgtagtaa aagtgacaaa gagaataaac aagctagtac tggtaagaaa
    13261 ttagaattaa aatatgctag tggatttagt gttgaagatt tagaagatgg aattaaaaaa
    13321 gtaactgatg gagataatcg agaactgatt ttaatcccaa agaagattaa aattcctgaa
    13381 aaatataaaa atgctaatat agttagaacg cctgtggaca atgtattaat agcatctaca
    13441 acacaggctt gttctctgag aacaatagat gaactagata gtataaaagc cgtaacaaca
    13501 gaagagcagt actggactat taaagaaatt aaagatttaa tgaaagatgg aaaaatacat
    13561 tacgttggtt caaatttagc accagattat gaaaaaatag tagacttaaa tcctgactta
    13621 actatagtga gtagtggttt atcagaggct gatacaaaat ttattgacaa attaaaagaa
    13681 ttagggctta attatgttgt agacaatgag tataaagagc aaaatccatt tggaagaatg
    13741 gagtggacaa gtttaatagc tgcattttat gataaagaag atatggctac tagtgaacta
    13801 aataaaactg tacaaaaggt agaagaagta agtaaaaaaa taaaaaacaa agctaaacct
    13861 aaagttgtat gggcatctgt atatgaagga agtgcttata tagctcctaa agattcatat
    13921 gtggataata tgataaaaat ggctggtgga ataaatgcat gtgcttcaat agattcaaat
    13981 gaagggcgag taagtattga acaattgcat gaagttgcaa aagatgcaga tatatttgta
    14041 tactcatcaa gttcagatta tgcaccaaat ttagattcta taaaatctag tgcacctgta
    14101 ttggctgatt tggatgttgt aaaaaacggg aacctatggg tgtttgctcc agattattat
    14161 caatcagtag ataagacgga cgaattaata gtagatttag ttgagatgtt ccacccaggt
    14221 actacaggtg aaaaaatcaa acattatata aattatgata aatagtacag agaggacaca
    14281 aaaagatagg ttttatagat tttagttaat atagctttgc taagaggagt atacaaatgg
    14341 attttatcaa taaaatgaga ataaggaata caacaatatt tatagtatta attataagta
    14401 tgatacttac ttttttagtg tgtgtagcat ttggctctgt aaaaattgaa tttaaagaag
    14461 taatagatgt tgtattaaga ggtatggata atacagaaca ttataaaata atatacaata
    14521 taagaatccc tagagtactt gcaaccatgg taggtggagc atgcctagca gtatcaggta
    14581 ttttattaca gatatttttt aaaaacccaa tagttgaacc gtatatatta ggagtatctt
    14641 caggttctac tttatcagta gctctcatga ttttgggagg atacacattg ggatttgaga
    14701 gtgtaaattc aatgagtata tttgtagcag cttttatagg agctttaatt gtaatgtcta
    14761 tagtcatttt atttgcaaat aaggtaaaga atataacaac tcttttaata ataggaatta
    14821 tgaccggata tgtatgtagt ggtataacaa atgtgttaca atcatttgca aatagtgata
    14881 aattaaaaga atttactatg tggtctatgg gaagtttttc tggatttaca tgggaaaagg
    14941 tagaaatact tataatagtt ggtatattag gtcttttgat gactgtattc ataataaaac
    15001 ctttaaatgc ttttttacta ggagaagagt atgcaaaaag tattggcata aatataagat
    15061 tttttagagt tttgatagta tttatatcta gtatattagc agcaatagta tcagcatttg
    15121 caggacctat agggtttatt ggacttgcag tgccacaaat ttcaaaaatg atatttaaaa
    15181 catcagataa tagagttttg ataccagtag taatattttt aggcagtata gttacagctc
    15241 tttgtgattt aatatcaaga gtaattttat caccagtaga attaccaata agtacgataa
    15301 catctttatt aggagctcca attgtagtaa tgttattggt gaaaaggaag gatagggctt
    15361 agacatgttg aaaactaata atttaagtgt aggatacaat aacaaagttg ttataagtaa
    15421 tataaatgta gaagtaaaaa atggagaaat actatgtctt ttgggaagta atggagctgg
    15481 aaaaactacc ctattaaggt ccttatctaa acttatatca ccaataaaag gtgaaatata
    15541 tttgaatggt gtaaacataa actgtatatc aagaaaagca ttatcaaaaa aaatggcttt
    15601 agtacttaca aatagattat taggtgattt aatgactgta caagatatag tcaatatagg
    15661 aaggtatcca tatacaggat tttttgggag tctatctaag aaagatttaa taatggtaga
    15721 tgaagcattg gagtctgtag atgccttaca tttaaagaaa agatattttg atgaactaag
    15781 tgatggagaa aaacaaaagg tgttggttgc aagggctctt gttcaagaac cagaaataat
    15841 tatattagat gagcctacaa ctcacttgga tataaaacat agattggaac tcataaacat
    15901 actgaaaaaa ttaagtaaag aaaagtcaat atcagtaata ctttcattgc atgaaataga
    15961 catagcatta aaaagttgtg ataaagttgc tcttataaaa aataataaag tcatagctta
    16021 tggtcagcct gaagatgtag tagatgagga tattataaat tcgctttatg aattggatga
    16081 taaaaacttt aatagtcttt taggttcagt agaaattagt aataaatcta aaaatgaagt
    16141 ttttataatt ggtggtgggg gtaaagcaac accaatttat agagctttta ctaaaaaagg
    16201 tataggtctg tattctggaa taatacatga aaatgatatt gattatgaaa ttggtagaac
    16261 tatggggata aagatgttta cagaaaatcc atttgagcct ataagtgatg agagtttcaa
    16321 tttggctatt agaaatttaa atgattccaa gattataata gatacaggat ttagtgtagg
    16381 agagacaaat aagaggaata tagatattat aaaagaggct ttaaaattgg ataaaaaagt
    16441 ttattctttt agaaatagag atgagagtaa gaagtattat gacagtttgg atagtaagat
    16501 agaacatata gataaagttt ctcaaataat caatagtgca gatataaata atttattata
    16561 atttatgaaa taaaatgtac ttatgtgcta tagaaaaaag agtatagatt ataatttttt
    16621 tgaaattaca atctatactc ttttgttatt ttgtttatgt atttatatat ttataaaact
    16681 ttagcatttt atagataacc aatagcttcc tctctagtta aaaaaaagtg aatccctgta
    16741 gtcgattctt tccatctatt ttcattaaaa tcttcagcta caatcgtttc tcctactcta
    16801 tatataaaat tttcatcagc atatgcacga gcacttttaa aagattcttt accatctata
    16861 ctagtaattg acagtacttt tgccttatca catctacaag cgtttgatgt agcagacact
    16921 ctttttgcgt cgctgggtat taataattgt accattctaa aattaaaaca ttttttatag
    16981 cctataaatg ctcctgtttc aggacaatac aatttaaaaa aacgggtact ttcatctgat
    17041 attactccat ttaaagtagc atgttctaaa tttgaatttt ctaaattagc tcctctaata
    17101 tctgagttag ataagtcaca aaatctaaaa cttgcaccac ttaagtctgc attttttaat
    17161 atagaatttt ttaatgaaca atccgaaaga taagaattat taaaaataga gttttctaaa
    17221 tctgcttttt ctaaatttaa attgataagg tcagaccacg aaaagtcaat attacttaag
    17281 cagtatcctc ttaagtccat attttctaat cttaattctt ttaaatctgc cttttctcca
    17341 gcattattgt ttttaagcca taaataatgt ttctcaagtg ttttttctaa ttcttgttta
    17401 gaaatagttt tcattaaaat caccttcata aatttatttt tatatatgta gtagcaaaat
    17461 agtcatatat ttaattatat aacaataaat aaaaaacttc taaataatat ataaaatatc
    17521 atcttgaaag tacttttttc aatatatcag aatatatttt taagctattt agagata
//
LOCUS       DAEPHU010000080        17262 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 01A10CD0081
            SAMN05941466-rid12468953.denovo.080, whole genome shotgun sequence.
ACCESSION   DAEPHU010000080 DAEPHU010000000
VERSION     DAEPHU010000080.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941466
            Sequence Read Archive: SRR6291087
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 17262)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17262)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068158.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 22:43:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,892
            CDSs (total)                      :: 3,805
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 87
            rRNAs                             :: 8, 1, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 55
            CDSs (without protein)            :: 55
            Pseudo Genes (ambiguous residues) :: 0 of 55
            Pseudo Genes (frameshifted)       :: 21 of 55
            Pseudo Genes (incomplete)         :: 28 of 55
            Pseudo Genes (internal stop)      :: 16 of 55
            Pseudo Genes (multiple problems)  :: 8 of 55
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17262
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941466-rid12468953.denovo.080"
                     /strain="01A10CD0081"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            complement(126..704)
                     /locus_tag="KR231_003048"
     CDS             complement(126..704)
                     /locus_tag="KR231_003048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HBH0005404.1"
                     /translation="MAYAKYLTKITDINKFYLENIINEGDIVIDATMGNGYDTRYLAE
                     KVGEKGFVYAFDIQEEAIKSTRKKLEKEGYTDRVKLIFDGHEKMNQYIKEEVSCVLFN
                     LGYLPRAKHSIITKPDTTLKAIKLSLEMLKENGVISIAIYTGHDGGQEEKDCIYNLVN
                     NLNQDEFNVLESKFLNQVNNPPQLILIEKKKA"
     gene            complement(762..1478)
                     /locus_tag="KR231_003049"
     CDS             complement(762..1478)
                     /locus_tag="KR231_003049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HBH0005405.1"
                     /translation="MRINKYIASCGIASRRKAEEIILGGRIKVNGSVVKELSFNIDEE
                     KDIVEFDNKKVKPSENYIYIVLNKPEGYITTVKDQFNRPSVIDILKDVRERVYPIGRL
                     DYETSGLLILTNDGDLTYKLTHPKHEIDKMYVASVKGIISDDEIRQFETGLKIEDYTT
                     APAKIRVTKENKEKNYSVCEITIHEGRNRQVRKMCKAINHPVLNLRRISVGKIVLKDT
                     KVGEYRYLTEDEIKYLKSIK"
     gene            1669..2754
                     /locus_tag="KR231_003050"
     CDS             1669..2754
                     /locus_tag="KR231_003050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HBH0005406.1"
                     /translation="MIIISKENIKYYLIVVFIGILFFKFINTPSDFISSIEGFLKFFS
                     PFLLAILLALLLNPLVMLFEIKFKAHRLLAIFLSYIFIGFILAFAIRLLIPSIANTLN
                     RLINEMPMYTDYIDSFIEKNMSNIYFLKTLIPHIQHSLDNLLKEASNFVGKIPKNFLI
                     YTLSISSMLFNMTMGFILSIYIIYDKEKIALGFKRFLYSSTARNKADNIIEFFRTTHD
                     IFYDYLLGRILDSLIIGIIAFLGFQFVIRIENALFLASIIFLGNIIPYFGPFIGAIPP
                     IAMTILYSPQKTIWVIAFLFILQQLDGNFIEPKVMGNQVGIGAIWVISAILVGQSLFG
                     FIGVFLSVPIAAVVKTYVDKYIDNRLQ"
     gene            complement(2909..3568)
                     /locus_tag="KR231_003051"
     CDS             complement(2909..3568)
                     /locus_tag="KR231_003051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0005407.1"
                     /translation="MRGRVILLISILSIFLVGCSFNKKDEINLVEQGKTYLEKHNYKK
                     AMESLSSALEEDSTNENARAMYMQAMRMSNMTEFEELKNYEGAIKELKLIEKIKNGSS
                     VIKEEATKKKEELTKLEKEQNEAEEQRKKKAKDTAGEDRYRVESDARKSSYSGSSKNN
                     KSSSKNNDKKSDSNKSDNSNSSSQNQEKPNNSNPTPAPTPQDTTGGSDSGGNSQNSNN
                     Q"
     gene            complement(3785..5077)
                     /gene="lysA"
                     /locus_tag="KR231_003052"
     CDS             complement(3785..5077)
                     /gene="lysA"
                     /locus_tag="KR231_003052"
                     /EC_number="4.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopimelate decarboxylase"
                     /protein_id="HBH0005408.1"
                     /translation="MKLHGTMTVNNDELYIGGVSCLELSKKYQTPLYVFDEALVRQNC
                     REYVEYFKAREGKNKVAYAGKAFLPLYMCNLINEEQMCLDVVSGGELYTAYKSNFPME
                     KVFFHGNNKTKEEINMGLDLGVGKFVVDNFYELDLLEALCEDKGKTQEIYFRITPGIE
                     AHTHDYIKTGQIDSKFGFALVNGDLFRAIEKLSEYKNIKLVGLHAHIGSQIFDVEPYI
                     DTVDIMMNLVKEIKEKFNIQLTEIDLGGGVGVYYSEGDKPKTIKEFCETIITKAETSC
                     KELGIEVPTLVIEPGRSIVANAGSTLYTVGSIKDIKDVRVYVSVDGGMTDNVRPSLYQ
                     ASYECSIVNKINHEAMNHVTIAGKCCESGDILIGDINIMDIKSGDILITTSTGAYGYS
                     MSSNYNKIPRAAVVSVFDGNDKIICKRQSYEDLLALEI"
     gene            complement(5095..6288)
                     /locus_tag="KR231_003053"
     CDS             complement(5095..6288)
                     /locus_tag="KR231_003053"
                     /EC_number="2.7.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate kinase"
                     /protein_id="HBH0005409.1"
                     /translation="MSIIVQKYGGSSVADTEKIKSIAENIIERRKENPQMVIVVSAMG
                     KSTDEYITLAKELSNEPSKRELDALMSTGEMISASLLSIALNALGCKAISYNAYQLNI
                     KTSGLHGKSQIDDINVNRIKNSLDEGNVVIVTGFQGINEDGDVTTLGRGGSDTSAVAL
                     AVKLNGKCEIYTDVDGIYFTDPRKYSKASKLDEIEYEEMLELASLGAQVMHSRSIELA
                     QKYGVEIYVGRTCGTEKGTYIRGGKDMKLEDKVITGLATSDDDSSITIKDFKAENISS
                     LFEDIATIGISVDMISQTAPILDKISVSFTVPKEELGECKKIVSKYTDEEHVVIDNNI
                     TKFSLVGLGMKNTSGVAAKVFKIFNENGIMIKLITTSEIRITCAINSDDKQVAIEKIA
                     EVFNI"
     gene            complement(6649..7266)
                     /locus_tag="KR231_003054"
     CDS             complement(6649..7266)
                     /locus_tag="KR231_003054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0005410.1"
                     /translation="MTNMEKEILLLISRVRCVTESQFRKIYGDQKRYNKKNFKKTLRK
                     MCSEYTLKKYPCDVDYYNYKDLSYVYYLNGSKLFKGDDLIKALVGSELVVRINTAGCD
                     VKRFYRNVSVDDVKYDLFIEYTDQFGNIKQVLVDVDLNNEIDISKYENLSKKIDKSTI
                     PFFKVPNVLVVTPDNLSELNDLERYDNEYSINFIDLGLNKLFNCI"
     gene            complement(7436..9136)
                     /locus_tag="KR231_003055"
     CDS             complement(7436..9136)
                     /locus_tag="KR231_003055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0005411.1"
                     /translation="MKRYLKTYGVALIIVIIYAFIKLPVLRLDFTSLFSVGIIFFVVA
                     GILDMMLDRNERASKMAKYNFSIAIALLVYIVVVPFITSTPVLHAKSYRELLGKVTES
                     KFTDDISPVSVNDIRLVDEDMAMKLGDKKLGEVPAIGSVSKLGKFHIQNVDGELYWVA
                     PLVHRDIIKWITSLSGTSGYVKVSASNPQDVQLVQEIDGKPIKIVYQPEAYLHQDLQR
                     HLYIHGIVNVGMTDFTLEINDEGRPYWVVSLYEHKIGYGGANATGIATVDAETGKINV
                     YDVKNTPKWVDRIQPQSFVTDQIKDWGVYVNGFLNSVISEKGVLVPTEGTSLVYGNDN
                     RSYWYTGITSSGGDESTIGFMLVDSRTKEARLYKQPGATETAAMKSAEGNVQEKNYEA
                     TFPVMYNILGQPTYVSSLKDKAGLVKRVAFVSVEDYNVLGIGEDKNEALRNYKDALES
                     KGNDLKLDNDLKDEVLEGTVTRISPDVRGGNTNYYVTLDSNKDIIFRATSKVSSELPL
                     TQVGDKVKISYSKEESGVIEMSEFDNLNIANFEDKKAKEKTGTDENTDSKDSENQGNV
                     "
     gene            complement(9533..10096)
                     /locus_tag="KR231_003056"
     CDS             complement(9533..10096)
                     /locus_tag="KR231_003056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0005412.1"
                     /translation="MNKVYIVTTYTGTILSYLIRNISKKLYTHVSISLNENLKPMYSF
                     GRLNPRNPFIGGFVEENINQGLYAIRKNTVCRVYSLEVDNLQYENLYKNIKLISDYRE
                     DYYYDTMALIYLLMNIQRQSEYKYVCSNFVADMLEKSEIDILNKQAFEVTPNDFYNLS
                     GLTLEYEGLLSEYNSRQHSYVSKIANI"
     gene            complement(10255..10968)
                     /locus_tag="KR231_003057"
     CDS             complement(10255..10968)
                     /locus_tag="KR231_003057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2140 domain-containing protein"
                     /protein_id="HBH0005413.1"
                     /translation="MGKVAKILLSLIVIVLVLVGIVVYILTPKERYDVSSQNNKIIDE
                     EYLSKGSYINSMEVVKNPLRMVGKISVSEEEFKNLIYTLMQKHGINELENNFVEMKNG
                     KIKVAGPYKVFGLVNSQYELELRPTLKDGNLVVSLENVKIGKFKLSDKMLEKILSNYN
                     KKVPFEVNGNKITLEKSYLYPITLKNISIKKGNVDLDMEVEIDLKSQINGALGYLKDS
                     GKVQDILNHLINLKKTSVG"
     gene            11260..12924
                     /locus_tag="KR231_003058"
     CDS             11260..12924
                     /locus_tag="KR231_003058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine--tRNA ligase/YqeY domain fusion
                     protein"
                     /protein_id="HBH0005414.1"
                     /translation="MSNETNSSNFIKNIIINDLETGKHDSIITRFPPEPNGYLHIGHA
                     KSICLNFGLAKEFNGKANLRFDDTNPLKEDVEYVESIKEDVKWLGFDWNELNFASNYF
                     DEMYKRALILIKKGKAYVCDLTQEEMREYRGTLTEPGKESPHRNRTIEENLDLFERMK
                     NGEFKDGEKTLRAKIDMSSPNINLRDPIIYRISHSTHHNTGDKWCIYPMYAFAHPIED
                     AIEGITHSICTLEFEDQRPLYDWFVKECEMENIPRQIEFARLNINNTVMSKRKLKQLV
                     DEGIVDGWDDPRVPTISGIRRKGYTAEALRNFCSEIGVSKVNSTVDSQMLDYFLRENL
                     QPKAPLTMGVLRPLKLIITNYPEDKIEMLEIENNAKDESQGKRLVPFSRELYIEQDDF
                     MEEPVKKYFRFFPGNEVRLKGAYFVKCTDVIKDENGNVVEIHGTYDPETKSGSGFTGR
                     KVKSTIHWVDAKSAIPCEFRLFEPLILDDIPENEGKHFLEQINPNSLEILQGFVEPTQ
                     IKDAKPFDKFQFVRNGFFSIDNKYTTDEKFVFNRIVPLKSSFKPGK"
     gene            complement(13031..13930)
                     /locus_tag="KR231_003059"
     CDS             complement(13031..13930)
                     /locus_tag="KR231_003059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YegS/Rv2252/BmrU family lipid kinase"
                     /protein_id="HBH0005415.1"
                     /translation="MKKVKLIYNPNSGEKKILSNLDTIIELYQEKNYLLIPYRLTIKE
                     PVKNAFKEVDSSYEHILIAGGDGTVDLVVNAMKELDIKIPIGILPTGTANDFSNALQI
                     SFDIKEAINEIINSKPKKIDIGKVNNKYFINVASAGMFTDVSQRINTDLKNSFGRISY
                     YIKGIEEALYMRKFKIKVSSEEMYYDGDMYLMLIFNGKTAGNINLAYKAEIDDGYLDV
                     IIFKGMPIPKSIPVLISVLRGDYLDQYNGNEILYFKTKKVHIECEDSLITDIDGEKGP
                     DFPLNIECIKDGIEVMGICSEKS"
     gene            complement(13957..14595)
                     /locus_tag="KR231_003060"
     CDS             complement(13957..14595)
                     /locus_tag="KR231_003060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003356606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactate utilization protein"
                     /protein_id="HBH0005416.1"
                     /translation="MDQNLNWLNEKRIEKTIKSLENNNMKGYLVSNKEELLKKIEEIV
                     KAGSLVGCGGSMTLFETGVIDFIREKYNFLDRYAKDIKPEEMKEIYRKSFSADAYFTS
                     TNAITEDGELYNLDGNGNRVAAMIYGPDKVIVIAGVNKIVKDVDEAIKRTKTIAAPAN
                     CKRLSTNTGCKTTGICIDCSSPGRICCSYTLIKRQLTPERIHVIFLNEDFGY"
     gene            complement(14932..15930)
                     /locus_tag="KR231_003061"
     CDS             complement(14932..15930)
                     /locus_tag="KR231_003061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4003 domain-containing protein"
                     /protein_id="HBH0005417.1"
                     /translation="MEQSFINGKVNLLIENYKALNEVKGSWQMGLIQHSCALAFTLKN
                     KKISPRLVEERIELIKKNTGLFSNFRGYNMFYMATLLSFESNPESSFKMILDIYKELK
                     SEKFWGDTYLPLTASIVYENREKMDYLTCISKMKIIYDYMRKKHPFLTSSDDYCNIAL
                     IAIHSKNLDEDLEYIEKCYEFLNENGFYKGNDLQALSQILLFSDDRTMLKCKKTIELK
                     KAFKENDCKMNYYGYPIIGAISLLDYREDEIIEEIKNVSNKLKEEKGFGNWSLGKSNR
                     VMISSAIVASIYADLIRNENNIGSITNNIFLNIVVAIQIACVMAATSAAIASSSSN"
     gene            complement(16028..16603)
                     /locus_tag="KR231_003062"
     CDS             complement(16028..16603)
                     /locus_tag="KR231_003062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424324.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0005418.1"
                     /translation="MKLKEALITCVVCSVCLTPLLVNGETKIDADHCKESIVNIDTIV
                     KSGKSFNSKYNQGMEDYKNSDEYKLKVQKEKLQNQLGIKIKKLVPITFEVSYYTSLNQ
                     ENGYGAITATGDDLEDGFVANNHLSFGTKIIVDGKLKTVMDRGSSKYFSNSNAIDVFV
                     PKWSNESESEYYDRVNNMGRHYKKGYIIVEE"
     gene            16919..17182
                     /locus_tag="KR231_003063"
     CDS             16919..17182
                     /locus_tag="KR231_003063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0005419.1"
                     /translation="MIKNTKQITVEVNEILLQEMSKITNYENNILTDLINESIVNYIL
                     ENKKHNIENKDLEEVIKFYKKENTEKPKSAARAIAEAKTHTLY"
BASE COUNT         5633 a         2848 c         1827 g         6954 t
ORIGIN      
        1 catatttaga tgtatatttt gttttgagaa taaactgttg tatacttatt atttaaagta
       61 tttttaatag gtcacactat atatattaac tcttaataca atcttgtcaa gttttttagt
      121 atttattatg cttttttctt ttcaattaaa atcaattgtg gtgggttatt gacttgattt
      181 aaaaacttag attctaaaac attaaattca tcttgattta aattattgac aaggttatat
      241 atgcaatctt tttcttcttg acctccatca tgccctgtat atatggcaat gcttattact
      301 ccattttctt ttaacatttc taaacttaac tttatagcct ttaaagttgt atctggtttg
      361 gttataattg aatgtttcgc tcttggaaga taacccaaat taaataaaac acatgaaact
      421 tcttctttta tatattgatt cattttttca tgcccatcaa atatcaattt tactctatct
      481 gtatatcctt ctttctctag tttctttctt gtagacttta ttgcttcttc ttgtatatca
      541 aaagcatata caaagccctt ttctccaacc ttctcagcta gataccttgt atcataccca
      601 tttcccatag tagcatcaat tactatgtca ccttcattta taatattttc taaataaaat
      661 ttatttatat ctgtaatttt agttaaatac tttgcatatg ccataatact atttctccct
      721 actattaact ttatttcatt ttttctcaat ttatttttat cttattttat tgattttaaa
      781 tattttattt catcttctgt taggtatcta tattctccaa ctttggtgtc ttttaatact
      841 attttcccca cagaaatcct tcttaaattt aaaactggat gatttatagc tttgcacatt
      901 tttcttactt gtctatttct accctcatgt atagttattt cacacactga ataatttttt
      961 tctttatttt ctttagttac ccttattttg gcaggtgccg ttgtgtaatc ttctattttt
     1021 agtcctgttt cgaattgtct tatctcatca tcacttataa ttcccttcac acttgccaca
     1081 tacattttat caatttcatg ctttggatgg gtaagcttat atgttaaatc gccatcatta
     1141 gtaagtatta ataaaccact agtttcataa tctaatctcc ctattggata tactctttcc
     1201 cttacatctt taagtatgtc tattacactg ggtctattga attggtcttt tactgtagtt
     1261 atatatccct ctggtttatt taatactata tatatataat tttcacttgg ttttactttt
     1321 ttattatcaa attctactat gtctttttct tcatcaatat taaaagataa ctcttttact
     1381 acacttccat ttacctttat tcttcctcca agaattattt cttctgcttt tcttcttgat
     1441 gctattccac aagaagctat atacttatta attctcatac ttaatccttc cttatcttaa
     1501 attatgtgtg tttaatattt ttatcaatgt taattttgct acattattat actatactag
     1561 accttaatta aaaacaagca aaaaaattat ttaattttcc taaataattg taatttcttt
     1621 tcacatacta ttaatatgta atagctgact aaacactatt ttaaggaagt gattattatt
     1681 tcaaaggaaa atataaaata ttatttaata gtcgtgttta ttggaatttt attttttaaa
     1741 tttattaata ctccatcaga ctttatatct agtattgaag gattcttaaa gttttttagc
     1801 ccatttttat tagctatttt acttgcttta cttttaaatc cacttgtgat gctttttgag
     1861 ataaaattca aagcacatag acttttagcc atttttttat cttatatatt tataggtttt
     1921 attttagcct ttgccattag gttattaatt ccatcaatag ctaatacatt aaatagattg
     1981 ataaatgaaa tgcctatgta tactgattat atagatagtt ttatagaaaa aaatatgtca
     2041 aacatatatt ttctaaaaac tttaattcct catatacaac atagtttaga taatttatta
     2101 aaagaagcaa gtaattttgt tggtaaaatt cctaaaaact tcttaatcta tacacttagt
     2161 atatcttcta tgctatttaa tatgacaatg ggatttatac tatctatata cattatatat
     2221 gacaaagaaa aaattgcatt gggatttaag agatttctat attcttctac tgctagaaac
     2281 aaggcagata acattataga attttttagg actactcatg atattttcta tgattattta
     2341 cttggtagaa tattagactc tcttattatt ggtataattg catttttagg atttcaattt
     2401 gttatcagaa tagaaaatgc tttattttta gcttcaataa tattcttagg taatataatt
     2461 ccctattttg gtccttttat tggtgcaatc cctccaatag ccatgactat attatatagt
     2521 ccacaaaaaa ctatatgggt cattgcattt ctatttatat tgcaacaatt agatggaaat
     2581 tttatagaac caaaagttat gggtaatcaa gttggtatag gagctatatg ggtaatatct
     2641 gctattttgg tgggacaatc tctatttggt ttcataggag tttttctttc agtaccaata
     2701 gctgctgttg taaaaactta tgttgataaa tatatagata atcgtttaca atagcttatc
     2761 tctactgtga ctttaatttt tagtttaaaa tttaactgtt atttattaaa ttatttctca
     2821 aaaaatatct cttagtaaga aaaaattgct aagagatatt ttttataata tataatttgt
     2881 tcattaaatt tatgcatata ttttatactt attgattatt tgagttttga gaatttccac
     2941 cactatctga accaccagta gtatcttgtg gagttggtgc tggtgttgga ttactattat
     3001 ttggcttttc ttgattttga gaagaactgt tactattgtc agacttatta ctatctgatt
     3061 ttttatcatt atttttagaa ctagatttat tatttttact acttccacta taagaagatt
     3121 tccttgcatc tgattcaact ctatacctat cttctccagc cgtatctttt gcctttttct
     3181 ttctttgttc ctctgcttcg ttttgttctt tttctaattt agttaactct tctttctttt
     3241 tagttgcctc ttctttaata acagaggaac catttttgat tttctctata agtttaagtt
     3301 ccttgattgc accctcataa ttttttaatt cttcaaactc cgtcatattt gacattctca
     3361 tagcttgcat atacatagct cttgcattct cattagtact atcttcttcc agtgcagagg
     3421 ataatgattc catagctttt ttatagttat gtttttctaa atatgttttt ccttgctcta
     3481 ctaaatttat ttcatctttt ttattaaatg aacatcctac aagaaatata gataatatcg
     3541 atattaataa aattactctt cctctcatta aatccctcct tgtcatatac tttaaatttt
     3601 atcataatta taaagttttt aaaatatttt atatttatta caagaaattt gttagtaaaa
     3661 caaaaaataa gcagatatgc tacgaacgat acaataaacc aaaaattaat ttagagatac
     3721 atatcctagc aaatctgctc ataataaact ttaatattta atttttatta tatacttctc
     3781 cattttatat ctctaaagct aataagtcct catagctttg tctcttacaa attatcttat
     3841 catttccatc aaatactgat actactgctg ctcttggtat tttattataa tttgaagaca
     3901 ttgaatatcc atatgcacca gttgatgttg ttataagtat atctccactt ttaatatcca
     3961 ttatgtttat atctccaatt aatatatctc cactctcaca acattttcca gctattgtta
     4021 catgattcat agcctcatga ttaattttat tcacaatact acactcataa ctagcttggt
     4081 acaacgaagg tcttacatta tctgtcatac ctccatctac acttacataa accctaacat
     4141 cttttatatc ttttatagaa cctactgtat acaatgtact tcctgcattt gcaactattg
     4201 accttcctgg ttctattacc aatgtaggta cttctattcc aagctcttta catgaagttt
     4261 ctgctttagt gattatggtt tcacaaaact cttttatagt tttaggttta tctccttcgc
     4321 tataataaac gccaactcct ccacctaggt caatttctgt tagttgtatg ttgaattttt
     4381 cttttatttc ttttaccaag ttcatcatta tatccactgt atctatgtat ggttctacat
     4441 caaatatttg tgaacctata tgagcgtgaa gacccacaag tttaatattt ttatattcac
     4501 ttaatttttc tattgctcta aataaatctc catttactaa agcaaatcca aatttagaat
     4561 ctatctgtcc agtttttata taatcatgtg tatgagcttc tataccagga gttattctaa
     4621 agtatatctc ttgagtttta cctttatctt cacataatgc ttcaagcaaa tctaattcat
     4681 aaaaattatc caccacaaat ttacctacac ctaaatctaa tcccatgttt atttcttctt
     4741 tagtcttatt gtttccatga aagaaaactt tttccatagg aaaatttgat ttataagctg
     4801 tatataactc gcctcctgaa actacatcta aacacatttg ttcttcattt ataagattac
     4861 acatgtaaag aggtaaaaaa gctttccctg cataagcaac cttatttttt ccctctctag
     4921 ccttaaaata ttctacatat tctctacaat tttgtctaac taaagcttca tcaaatacat
     4981 aaagtggagt ttgatatttt ttactaagtt ctaaacaact cactcctcca atatataatt
     5041 catcattatt tacagtcata gttccatgaa gtttcataat agcctcccca aattttatat
     5101 attaaatact tctgctattt tttctatagc tacttgctta tcatcagaat ttatagcaca
     5161 agttatacga atctctgatg tagttataag ttttatcatt ataccatttt cattgaatat
     5221 cttaaatact ttagcagcaa ctccagaagt atttttcata ccaagaccta ctaaagaaaa
     5281 tttagtgata ttattatcaa tcactacatg ttcttcatct gtatatttag atactatctt
     5341 tttacattct cccaactctt cttttggaac tgtaaatgat acacttatct tatctaaaat
     5401 aggtgcagtt tggcttatca tatctacact tatacctata gttgctatat cttcaaataa
     5461 gctagatata ttttcagctt taaaatcttt tattgttata gaactgtcat catcactagt
     5521 agctaatcct gttattactt tatcctctaa tttcatgtct tttccccctc ttatatatgt
     5581 tcctttttct gtaccacatg tacgtccgac atagatttca acaccatatt tttgtgcaag
     5641 ctctatactt cttgaatgca ttacttgtgc tcctaaactc gctaactcaa gcatttcttc
     5701 atattcaatc tcatcaagtt tactagcctt tgaatatttt cttgggtctg taaaataaat
     5761 tccatcaaca tctgtatata tctcacattt tccatttaat ttaaccgcaa gagctacagc
     5821 agatgtatct gaaccacctc ttccaagagt ggttacatca ccatcttcgt tgattccctg
     5881 aaatccagtt actatcacga catttccttc atctaaacta tttttaattc tgtttacgtt
     5941 tatatcatca atttgagact ttccatgaag accactcgtt tttatattta actggtaagc
     6001 attataactt atagctttac atccaagtgc atttaatgct attgataata aagatgctga
     6061 aatcatttca ccagtagaca ttaaagcatc taattccctc ttactaggtt cattactcaa
     6121 ttcctttgct aaagttatat attcatcagt ggattttccc atggcagaca caactattac
     6181 catttgtgga ttttcttttc ttcgttctat tatattttct gctattgatt ttattttttc
     6241 agtatctgct actgaacttc caccatattt ttgaacaatt atactcatgc tttctccccc
     6301 tcaagctaaa ttttgataaa taaaaacgcc caaaggtata ctttggacgt gtaaatttca
     6361 tagaccaagt aaccttgtag ctcaccactt taaaagtgac agccttatgc atattctgca
     6421 taagtccaga aaatttgtcc gtcaacaaaa tttcttcggc tatataccct ttcatcaatt
     6481 atcaacgctt accagctcct attgaatact attgaataca gctacctcta ccctaggctc
     6541 attattttta attaatttat taatatagtt ttatcatatt ctatataata ttgcaacaat
     6601 tattttacaa aatgtggcaa atcgatagtt ttcttttcta aagttagctt atatacaatt
     6661 aaatagttta tttaatccta aatctataaa atttatgcta tactcattat catatctctc
     6721 taaatcattt aattcggata gattatctgg tgtaactacc aaaacgtttg gtactttaaa
     6781 aaatggaatt gtagatttat ctattttttt agaaagattt tcgtatttag aaatgtctat
     6841 ttcattattt aagtcaacat caactaaaac ttgctttata ttaccaaatt ggtctgtata
     6901 ttcaataaat aaatcgtatt tcacatcatc tacactaaca tttcggtaaa atctttttac
     6961 atcacaacct gcagtattga ttctaacaac taattctgat cctactagag cctttattaa
     7021 atcatctccc ttaaaaagtt tactaccgtt taaatagtat acataagaga ggtctttata
     7081 attataataa tccacatcac aaggatattt ttttagtgta tattcactac acatttttct
     7141 caaagttttt ttaaaatttt ttttattgta tcttttttgg tctccataaa tttttctaaa
     7201 ttgagactct gtaacacatc taaccctgct aattaaaagt aatatctctt tttccatatt
     7261 cgtcatagta cattctcctt gaagtattat ttgcaaagtt gtactaatat tatattaatt
     7321 ttatgacatt aaatttacaa agaattaaaa taaaatagct aatttttata gaattaaatt
     7381 ctataaaaat tagctatcac tatgttaaat actattatca atctttttat ttaaattata
     7441 cattaccttg attttcagaa tctttggaat ctgtattttc atcagttcct gttttttctt
     7501 ttgctttttt atcttcaaag tttgcaatat ttaggttatc aaattctgac atttctatta
     7561 caccagattc ttcttttgaa tacgatattt tgactttatc accaacctga gtcaatggca
     7621 attcgctaga tacttttgaa gtagccctaa atattatatc tttatttgaa tctaaagtta
     7681 cataataatt agtgttacca cctcgcacat ctgggcttat tcttgtcact gtgccttcta
     7741 atacctcatc ttttaaatca ttatcaagtt ttaaatcatt acccttagat tctaatgcat
     7801 ccttatagtt tcttaatgct tcattcttat cttcacctat tccaagtaca ttataatctt
     7861 caacagatac aaatgcaact ctcttaacaa gaccagcctt atcttttaat gatgatacat
     7921 atgttggctg acccaatata ttatacatta cagggaacgt cgcttcataa tttttttctt
     7981 gaacattacc ttcagctgat ttcattgcag ccgtttcagt agctcctggt tgtttatata
     8041 atctagcttc ttttgttcta gaatcaacta acataaatcc aattgtagat tcatctccac
     8101 ctgaagatgt tatacctgta taccaataag acctgttatc attgccataa actagtgatg
     8161 taccttctgt tggtactaaa actccctttt ctgatataac agagtttaaa aatccattaa
     8221 cataaacacc ccagtcttta atttggtctg ttacaaagct ttgtggttgt attctatcca
     8281 cccatttagg cgtgttttta acatcataaa catttatttt tccagtttct gcatcaacag
     8341 tggctattcc tgttgcattt gctcctccat agccaatttt atgttcatat aaacttacaa
     8401 cccaataagg tcttccttca tcatttattt caagagtgaa atctgtcata ccaacattta
     8461 caataccatg tatgtataaa tgtctttgta aatcctgatg taagtaggct tctggttggt
     8521 aaactatctt tattggcttt ccatctattt cttgaactaa ttggacgtct tgaggattac
     8581 tagctgatac ttttacataa ccacttgtac cacttagaga tgttatccat ttaattatgt
     8641 ctctgtgaac aagaggcgct acccagtaca actctccatc tacattttgt atatgaaatt
     8701 ttcctaattt ggatacactc cctattgcag gaacttctcc aagctttttg tcacctaatt
     8761 tcattgccat atcttcatct acaagacgaa tgtcatttac actgacaggg ctaatgtcat
     8821 cagtaaattt actttcagtt acttttccca atagttctct atatgatttt gcatgaagta
     8881 caggtgtaga agttataaag ggaactacta caatatacac aagcaaagct attgctattg
     8941 aaaaattata tttagccatt ttagatgctc tttcatttct atctaacatc atatctagta
     9001 ttcctgctac aacaaagaaa attattccta ctgaaaataa agatgtaaaa tctaatctta
     9061 gtacaggtaa tttaataaat gcataaatta ttacaattat taatgcaact ccatatgttt
     9121 taagatatcg tttcatttaa tactcctctc taaaaaatgt tattattact attatatcca
     9181 tatatttaca aaaaataaat atttatcata tttattatat attaagatat ctttatatat
     9241 ttatagttct gcttattcaa ctatatttaa cattatacgt gtatgtataa atacttttta
     9301 tacactgttt gtactatcca tcccgcacct aaaggagtgg gatttttgca ctattctgta
     9361 ttatatatat ccaaaaatat tataaaaata caaatattag cagaaattta aaaactgaag
     9421 aaagtattct aactaagatt tacaaattct taatcctatc gaagttaaac tactatcttc
     9481 agcctaatta tctagcaata tttttttata tgaaaaactc taaatcaagt ttttaaatgt
     9541 ttgcgatttt tgatacataa gaatgttgtc tagaattata ttctgataat aaaccttcat
     9601 actctaaggt taagccagat aaattataaa aatcatttgg cgttacttca aatgcttgtt
     9661 tatttaaaat gtctatctca cttttttcta acatgtcagc aacaaaattt gaacatacat
     9721 atttatattc agattgtctc tgaatattca ttagtaaata tattaatgcc attgtatcgt
     9781 aatagtaatc ttctctataa tcactaatta attttatatt tttatataga ttttcatatt
     9841 gtaaattatc tacttctaac gaatataccc tacacacagt gttttttctt atagcatata
     9901 atccttgatt tatattttct tcaacaaatc ctccaataaa tggattcctt ggatttagcc
     9961 ttccaaaaga atacattggt tttagatttt catttaatga tattgacaca tgtgtataca
    10021 gctttttact tatattcctt attaagtaag ataatatagt tcctgtatat gttgttacaa
    10081 tatagacttt attcatcatt tccccccaat ctagtaacta aataatatta tacacttaca
    10141 atttaatatc ataagatatt ctaacataat aaatgtggtt ttacaaattt tgattttaag
    10201 gtactttaat attatataat ataataaaaa tataaatata agttttctat atttttaacc
    10261 aacagatgtt ttcttcaaat taatcagatg atttagtata tcttgaacct ttccagagtc
    10321 ctttaaatat cctaatgccc catttatttg tgattttaaa tctatttcta cttccatatc
    10381 caaatcaaca tttccttttt ttatagatat atttttaagt gttattggat aaagataact
    10441 tttttccaaa gtaatcttat ttccattaac ctcaaatgga acttttttat tgtagttact
    10501 taatattttt tctagcattt tatcacttag tttaaatttt ccaattttca cattctcaag
    10561 acttacaact aagtttccat cctttaaagt aggtctcaat tcaagttcat attgactatt
    10621 taccaaacca aataccttat atggtcctgc tacctttatt ttaccatttt tcatttcaac
    10681 aaaattattt tcaagttcat taattccatg cttctgcatc aatgtatata ttaaattttt
    10741 aaactcttcc tctgaaacag atatttttcc aaccattcta agtggatttt ttactacctc
    10801 catagaattt atatatgagc cttttgataa atattcttca tctatgattt tattattttg
    10861 tgaactaaca tcatatcttt cttttggtgt caagatatat acaacaattc ctacaagtac
    10921 taaaacaata acaattaaac ttaacaaaat ctttgcaacc tttcccataa tcgtctcctt
    10981 tacaaatctg tcatcagatt taaaataaat ttagataact aacttcacat aatattctta
    11041 acaatataca tactataata cagtctttta aaaattaatt caaccaatct aatgttttgt
    11101 aaataaactg taaaaacatg tttttagtat aaaagttaat attttgcata atactcttaa
    11161 ttacaccttt atttttttct aatcttggat taaaattaat attatgcaat acagtgtagt
    11221 gttctgtatt ataatcaaat taaataggag gtatagaata tgtcaaatga aacgaactca
    11281 tctaacttta taaagaatat tattataaac gacttagaaa caggaaaaca tgacagtatc
    11341 ataactcgtt ttccacctga gccaaacgga tatttacata ttggtcatgc aaaaagtata
    11401 tgtcttaatt ttggattagc taaggagttt aatggaaaag ctaatttaag atttgatgat
    11461 acaaacccat taaaagagga tgttgaatat gtagagtcca taaaagaaga tgtaaagtgg
    11521 ttaggatttg attggaacga gttaaatttt gcatctaact actttgatga aatgtataag
    11581 agagctttaa tactaataaa aaagggtaaa gcttatgtat gtgatttgac acaagaggaa
    11641 atgagagaat atcgtggtac tctaactgaa ccaggaaaag aaagtcctca tagaaacaga
    11701 actattgaag aaaaccttga tttatttgaa agaatgaaaa atggtgaatt taaagatggt
    11761 gaaaaaacat taagagccaa aatagatatg tcttctccaa atataaacct tagagaccca
    11821 attatatata gaatatctca ttcaacacac cataatacag gagataaatg gtgcatatat
    11881 cctatgtatg cttttgctca tccaattgaa gatgcaattg aaggaataac tcactctata
    11941 tgtactttag agtttgaaga ccaaagacct ctttatgatt ggtttgttaa agaatgtgag
    12001 atggaaaata tacctagaca aatagaattt gctagactta atataaataa tactgtcatg
    12061 agtaaaagga aattaaaaca acttgtagat gagggtattg ttgatggttg ggatgaccct
    12121 cgtgttccta caatatccgg aatcagacgt aagggatata ctgcagaagc attgcgcaat
    12181 ttctgtagtg aaataggggt atcaaaagtt aactctacgg tagatagtca aatgcttgat
    12241 tatttcctaa gagaaaactt acaaccaaag gctcctctta ctatgggagt tttaagacct
    12301 ttaaaactta ttataactaa ttacccagaa gataagattg agatgcttga aatagagaat
    12361 aatgctaaag atgaatctca aggaaagaga ttagttcctt tctctagaga attgtatata
    12421 gaacaagatg attttatgga agaacctgtt aagaaatatt ttagattttt cccaggaaat
    12481 gaagtccgtt taaaaggtgc ttattttgta aaatgtactg atgtaattaa ggatgaaaat
    12541 ggaaatgtag ttgaaataca tggtacttat gaccctgaaa ctaagagtgg ctctggcttt
    12601 acaggacgta aggtaaaatc tacaatacat tgggttgatg ctaaatcagc tatcccatgt
    12661 gaatttagat tatttgaacc attaattctt gatgatatac ctgaaaatga aggtaaacat
    12721 ttcttagaac aaataaatcc taattcattg gaaatattac aaggttttgt tgaacctaca
    12781 cagataaaag atgctaaacc ttttgataaa ttccaatttg ttagaaatgg attctttagt
    12841 atagataata aatatacaac tgatgaaaaa tttgtattta atagaatagt tcctctaaaa
    12901 agttctttta aaccaggtaa ataatcttac aatcaaaaaa tgaagactta aaatataaat
    12961 tacttctact ataaataaac ttagttagaa gtaatttttt atttgagtct tcatcattta
    13021 ctttaaatga ttaacttttt tcactacaga ttcccatgac ttctattcca tcttttatgc
    13081 attctatgtt aagaggaaaa tctggtcctt tttctccgtc aatatctgtt ataagtgaat
    13141 cttcacattc tatatgcacc tttttagttt taaagtatag tatttcattt ccattatatt
    13201 gatctaaata atcacctcta agcacactta tcaaaactgg tattgatttt ggtattggca
    13261 ttcctttaaa aataattaca tccaaatatc catcatctat ttcagcctta tatgctagat
    13321 ttatatttcc tgctgttttg ccattaaaaa tcaacataag atacatatct ccatcataat
    13381 acatttcctc agaagatact tttatcttaa atttcctcat atacaatgct tcttctattc
    13441 cctttatata ataagaaatt cttccaaatg aattttttaa gtctgtgttt atcctttgtg
    13501 atacatccgt aaacatacca gcacttgcaa catttataaa gtacttatta ttgactttcc
    13561 ctatgtctat tttctttggt tttgaattta tgatttcatt tatagcttct tttatatcaa
    13621 atgaaatttg aagagcattt gaaaaatcat ttgcagttcc tgtaggcaaa attccaattg
    13681 gaatttttat gtctaattct ttcattgcat ttactactaa atctacagta ccatcaccac
    13741 cagctatcaa tatgtgttca taagaactat caacttcctt aaatgcattc tttacaggtt
    13801 ctttaatagt taatctatag ggtatcaata aataattttt ttcttgatat aattctatga
    13861 tagtgtctaa atttgataat atcttttttt cacctgaatt aggattgtat ataagtttta
    13921 cttttttcat tatttctcct tactcatttt attcttttag tatccaaaat cttcatttaa
    13981 aaaaatcaca tgtattcttt ctggtgttaa ttgtcttttt ataagtgtat aactacagca
    14041 tattcttcct ggacttgaac agtctataca tataccagta gtcttacatc cagtatttgt
    14101 acttaatctt ttacaattgg ctggagcagc tattgttttt gttcttttta tagcttcatc
    14161 tacatcttta actattttat ttactcctgc tataactatt actttatcag gtccatatat
    14221 catagcagca actctattcc cattcccatc taaattgtaa agttctccat cctctgttat
    14281 cgcattagta cttgtaaaat aagcatctgc agaaaatgac tttctatata tttctttcat
    14341 ttcttctggt ttgatatctt ttgcatatct atcaagaaaa ttatattttt ctcttataaa
    14401 atcaatcact cctgtttcaa ataaggtcat agaacctcca catcctacta gagaacctgc
    14461 tttaactatt tcttcaattt ttttaagaag ctcttctttg ttacttacta aatacccttt
    14521 catattattg ttttccaaag attttattgt tttttctatt cttttttcat taagccaatt
    14581 taaattttga tccattttaa cttccccctt atttttaata tgtacttaat tatttataaa
    14641 ctttattttc tttataagtt tattttagta catctaaaaa aaaatacaat ataaaactta
    14701 aatagtttta cataattttt tccaaaataa cttactcaat caaaaaagga aagtagatgt
    14761 actattctac tttccctata ttgtatgtag tatttattgc ctaaaatcta tatattaatt
    14821 atatgtttca tattatataa tatcacagtt aattaaaatg taatactatc ttctttttaa
    14881 acatataaat tgtattatta aatttaatat atccaacttc aataaatctt attaatttga
    14941 tgaagaagat gctatagctg cacttgttgc tgccattaca catgcaattt gaatagcaac
    15001 aacaatattt aaaaatatat tattagttat agagcctata ttattctcat ttcgtatcaa
    15061 atctgcataa attgaagcta caatagcaga actaatcatt actctattac tttttcctaa
    15121 agaccaattt ccaaagcctt tttcttcttt aagtttattt gaaacatttt ttatctcttc
    15181 tattatttca tcttctctat aatctaataa tgaaattgct cctattattg gatatccata
    15241 ataattcatt ttacaatcat tttctttaaa tgctttttta agttcaatag tctttttaca
    15301 tttaagcata gttctatcat cactaaataa aagaatttgg gataatgctt gtaaatcatt
    15361 tcctttataa aaaccatttt catttagaaa ttcataacat ttttctatgt attctaaatc
    15421 ttcatctaaa ttttttgaat gaattgcaat aagtgctata ttacaatagt catcactaga
    15481 agttagaaat ggatgttttt tcctcatgta atcatatatt attttcattt ttgatataca
    15541 tgtaagataa tccattttct ctctattttc ataaactatt gatgctgtaa gtggtaaata
    15601 tgtatcgccc caaaactttt cacttttaag ttctttgtat atatctaaaa tcatcttaaa
    15661 actactttct ggatttgatt caaacgaaag tagtgttgcc atataaaaca tattatatcc
    15721 tctaaaatta gagaataatc cagtattttt tttaataagc tctattcgtt cttccactaa
    15781 tctaggactt attttcttgt tcttaagggt aaatgcaagt gcacaactat gttgtatcaa
    15841 tcccatttgc caagaacctt taacttcatt taatgctttg taattttcta ttaataagtt
    15901 tacttttcca tttataaacg attgttccat attgccctcc tagtaatata tctcattgta
    15961 ctaatagttt tatatttatt atatatatat taaatactac aatcaataca tattacttca
    16021 aagaacatca ttcttcaaca ataatgtagc cttttttgta atgtcttccc atattattga
    16081 ctctatcata gtactctgat tcactttcat tactccattt gggcacaaat acatctattg
    16141 cattagaatt actaaaatac ttactagacc ccctatccat aacagttttt aattttccat
    16201 ctacaataat cttagttcca aaacttaagt gattgtttgc tacaaaacca tcttctaaat
    16261 catctcctgt agcagttatc gctccatatc cattttcttg attaagactt gtgtaataac
    16321 taacttcaaa agttataggt actaacttct ttattttaat acctaactga ttttgtagtt
    16381 tctccttttg tactttcaac ttatactcat cactattttt ataatcttcc ataccttgat
    16441 tatacttgga attaaagctt ttacctgact ttactatagt atctatattt actatagatt
    16501 ctttacaatg atctgcatct atttttgttt ctccatttac caataatgga gttaaacata
    16561 cactacatac aacacatgta atcaatgctt ctttaagctt cataaattcc ccccttatta
    16621 ttttgatata ttagcatatt taatattata tgtctacatt tagatttaaa taccacaccc
    16681 atttgcttta agaagttgtc ttatatttaa ttcaccttaa acacttataa atcctctatc
    16741 ttagaatcat atagaataaa gcttttatca ttaaatattt tttattaatc ttttaaaatc
    16801 taaaactact ttatctaatt ttctcttttt tagaatttaa gaattaaaat tctataattt
    16861 taaaacatat tgaatttatt tttttgagat gatataattt tcttaagagg tggttgatat
    16921 gataaaaaat acaaaacaaa ttacagtaga agttaatgaa attttattac aagaaatgtc
    16981 taagataact aattacgaaa ataatatttt gacagatttg ataaatgaat caattgtaaa
    17041 ttatattctt gaaaacaaaa aacataatat tgaaaataaa gatttagaag aagtgattaa
    17101 attttataaa aaagaaaata ctgaaaaacc taaaagtgca gcaagagcta tagctgaagc
    17161 aaaaactcat actctgtatt aatcaaataa aaaagttcct aaaaactagg aactttttta
    17221 tattaataat tattaatata tctcaatatt tatctcaaat ct
//
LOCUS       DAEPHU010000081        17149 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 01A10CD0081
            SAMN05941466-rid12468953.denovo.081, whole genome shotgun sequence.
ACCESSION   DAEPHU010000081 DAEPHU010000000
VERSION     DAEPHU010000081.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941466
            Sequence Read Archive: SRR6291087
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 17149)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17149)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068158.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 22:43:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,892
            CDSs (total)                      :: 3,805
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 87
            rRNAs                             :: 8, 1, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 55
            CDSs (without protein)            :: 55
            Pseudo Genes (ambiguous residues) :: 0 of 55
            Pseudo Genes (frameshifted)       :: 21 of 55
            Pseudo Genes (incomplete)         :: 28 of 55
            Pseudo Genes (internal stop)      :: 16 of 55
            Pseudo Genes (multiple problems)  :: 8 of 55
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17149
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941466-rid12468953.denovo.081"
                     /strain="01A10CD0081"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            <1..651
                     /locus_tag="KR231_003064"
     CDS             <1..651
                     /locus_tag="KR231_003064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HBH0005420.1"
                     /translation="NKEILNMWVHDVKIPIAIIKLILEQNENLIDEKISDDIDSEIFR
                     IENSVEKILYLSRLEDFHKDFLIQEVNIEKIIRNIIKKYSKYFISKKIILDLNNLNFK
                     VLSDEKWLYFIFEQLLSNSLKYSSLGDNISIYCKRTKNYLQLRVEDTGCGIKKEDLNR
                     IFNKGFTGNNGRNNSKSTGLGLYLVKELCDKLGHKIDVDSEYNQYTKFTITFKCDL"
     gene            763..1992
                     /locus_tag="KR231_003065"
     CDS             763..1992
                     /locus_tag="KR231_003065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="efflux RND transporter periplasmic adaptor
                     subunit"
                     /protein_id="HBH0005421.1"
                     /translation="MSFLKKFKNKRFRNNSFKSNNFRNSSFGSSGFKSKNKGFKNNPF
                     KNKRFKIYAGIAVIILLILGVLAYVDSKNTELQANENFIETYTIPENEKIFINGMVVP
                     KQTKDFNISGDYELSDVNVTNGQKVNQGDLLFTAKNPTIIAEIDSLKSQLSQYKKQKI
                     SLSDIAENKDAIASINAQITALNSQIASLDKKAYDRVTAPFDGTVYLNDQTGNPDQPV
                     SFMTIQGLEFYMKGQASEQDLPKMKIDQMVNILVFSTDQKLTGRISFISDKPSTPNTE
                     MGAQQNTLSYYDINIAFDNQEGLVNGFHLQASLEVANSSFKIPASCVLKDNKHSYVFK
                     DLDGILKKQIVDVASQNDDFAVVRGGLEQGDIIIKHPTKEMKEGDPVQGDGVTAGSNN
                     GDTTPNKKVEEVTMDVN"
     gene            2000..2674
                     /locus_tag="KR231_003066"
     CDS             2000..2674
                     /locus_tag="KR231_003066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH0005422.1"
                     /translation="MLIKLENIQKYYKVGKDELHVLKSLNLEIESGEFVMIMGKSGSG
                     KTTLLNILGFLDVFDEGRYIFDGTDVTNLSENERSVFRNINIGFVFQQFNLIETLNVY
                     QNVELPLIYNKALKKSNREEIVKDKLSSVGLLDKLKQKPLQLSGGQQQRVAIARCLAN
                     DPQIIFADEPTGALDSETSREIMELLTRLNKQGKTIIMVTHDQDLTKYATKVIRLKDG
                     VFTSEV"
     gene            2677..3909
                     /locus_tag="KR231_003067"
     CDS             2677..3909
                     /locus_tag="KR231_003067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBH0005423.1"
                     /translation="MSLLKNSLANLKGHKLRVFVALLWIIIGITSVILVSSIGNGFQK
                     EIKKSVNNVNPNKTTISFESADNTGLTDDMSIFLKPFNAKDLEELSFVEGVERIAPSR
                     DGFNLDSVYSSQASFDKKTTYVDVGPVKKDSKINLICGRDFSLDDEKRKVILLTLQST
                     SEIFENPEDALGHGININGTIFEIIGVLDDSQQNQAGGFFGGYQDMQFTTSLVPKKAF
                     DTLMSQNSYSNEIYQLDLVSSKGYNVNEVANNVIAKLYEMHPGINGSYTTPDPTEQTA
                     YLESINSNVNKYVSIITVVAMFVGGIGVMNIMYVSVMERQREIGIRRAIGAKPRSILF
                     QFLVEAVFITVCGGILGTIVGFAATNYVSKYIGFEAIPSLNSLFYAIVATILTGVVFG
                     LIPAFKASKLDPIKAIYK"
     gene            complement(4195..5460)
                     /locus_tag="KR231_003068"
     CDS             complement(4195..5460)
                     /locus_tag="KR231_003068"
                     /EC_number="3.5.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420051.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotase"
                     /protein_id="HBH0005424.1"
                     /translation="MILIKNGRVIDPKSQRDENIDLIIKENKIYKIGKFDESDEYEKI
                     IDASGNVVAPGLVDVHVHFRDPGFTYKEDIESGAKSAARGGFTTVICMANTNPIVDNE
                     DTFNYVKEKSKNACINVLQAAAITKGFEGKELVDMEALKKAGVPGFTDDGLPLMDSNL
                     IMEAMIKAKELDVPLSFHEEDPSLVGNPGVNAGKVASELGLKGASSVAEDVMVARDCM
                     LALKTGAKVDIQHISSGVSVDMVRFAKYLGANVVAEASPHHFTLTEEDVLEFGTNAKM
                     NPPLRSKWDRDKIIEGLNDGTIEIIATDHAPHSKEEKDREFIKAPSGIIGLETSLALG
                     ITNLVHKNHLSMMQLIEKMSINPAKLYNLNIGFIEEGAVADIVIFNPEEEWTVESFVS
                     KADNSPFKGKSLYGKVNYTICNGEIVYNA"
     gene            complement(5513..6661)
                     /locus_tag="KR231_003069"
     CDS             complement(5513..6661)
                     /locus_tag="KR231_003069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF362 domain-containing protein"
                     /protein_id="HBH0005425.1"
                     /translation="MKSVSVRSCKTYNYEEVKLSIEKNLEDIGGIDKFVKKGSKVLIK
                     PNLLMKKKPEEATTTHPMVVKVVCEKLLELNCDITIADSPGGPYNQSSLKSIYKASGI
                     EEVANELGIKLNYDVSDVKIHSEKAHVLKYMDIIKPIVDSDYIINLCKLKTHIMATFT
                     GGTKNLYGCIAGLKKAEIHYRFPTEELFCENVLLDICDYIKPTLTIMDGIVGMEGDGP
                     SAGTTREIGVLLASQNPYAIDVVACKIISLLPNKVATIRGAIKRGYIQEDFSDIEILG
                     EDIKDLIIKNYKIPNVSKDLRLFSVKLPKFLNEPISKLITPKPVVRFQDCIKCGKCKE
                     ACPASTIEIGTKGAIIDLSKCIRCYCCHELCPKKAIDVKRNFVFKYVK"
     gene            complement(6761..7306)
                     /locus_tag="KR231_003070"
     CDS             complement(6761..7306)
                     /locus_tag="KR231_003070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH peroxidase"
                     /protein_id="HBH0005426.1"
                     /translation="MKKFVCTVCGYIHEGDAAPAQCPVCKVGADKFEEMKGEMVWADE
                     HRIGVAQGVDAEIIEGLRANFTGECTEVGMYLAMSRQADREGYPEVAEAYKRIAFEEA
                     EHAAKFAELLGEVVVADTKENLRVRVDAEYGATDGKLKLAKRAKELGLDAIHDTVHEM
                     CKDEARHGKAFLGLLNRHFGK"
     gene            complement(7529..8473)
                     /locus_tag="KR231_003071"
     CDS             complement(7529..8473)
                     /locus_tag="KR231_003071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DMT family transporter"
                     /protein_id="HBH0005427.1"
                     /translation="MQKNKKEGALLKKYFGEIGLIFIAIIWGSGFVATQFALDGGLTP
                     LQIITLRFFLAAIIMNLLFFKQIRANMGKKLLKAGGILGIFLFLAFTVQTIGLMYTTP
                     SKNAFITAANVVIVPFIGFILYRRKLDKIGIISSLVALIGIGILSLEADFSINFGDFL
                     TLICSFGFAFHIFFTSEFAKDNNPMALTAIQFTVAFLMSVVVQTFAGQLKMEAELSGY
                     MGTMYLAVFSTTIGFLFQTICQKRVDGTRTAIILSTEAVFGTIFSIIILKELITAKLV
                     IGSILIFVAIITAETKLSFLKSKKVKLKDSEESSLESI"
     gene            8859..9740
                     /locus_tag="KR231_003072"
     CDS             8859..9740
                     /locus_tag="KR231_003072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase"
                     /protein_id="HBH0005428.1"
                     /translation="MVKKRKKKTVTLTILVVIVIGIFSMAWADMSRKKEMKETQERLK
                     AERLEKERIEKEKNEPIIGAKKEAVKEYGYDAKIVWDKLNKYDYSNNGEKIVFLTFDD
                     GPSTTNTPQVLDILKRHGVRGTFFIKGDSLERKGANEILKRTFDEGNAIAHHSYTHDY
                     KKLYPNRSLNLDTFVNELNKTDEAMKKVLGKNFSSNVVRCPGGYMSWKNMEPLGNYLK
                     EKNMASIDWNALNADAEGKKKNAQELFEHAKKSSEGKEMVVLLMHDTYGKQETVNALD
                     QIITYFKDNGYQFKILI"
     gene            complement(9801..11009)
                     /locus_tag="KR231_003073"
     CDS             complement(9801..11009)
                     /locus_tag="KR231_003073"
                     /EC_number="6.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine--tRNA ligase"
                     /protein_id="HBH0005429.1"
                     /translation="MKSIDEQMRIIMKGVDDLIDEKELREKLIKSEKEGKPMIVKLGL
                     DPSAPDIHLGHTVVLRKMKQLQDLGHQIVIIIGDFTGKIGDPTGKSKARKALTTEQVL
                     ANAKTYEEQIFKVLDKEKTIVRFNSEWLAKLNFEDVIKLAATITVARMLEREDFKKRY
                     EGQMPISVHEFFYPLMQAYDSIALEADIELGGTDQRFNLLMGRSLQREFGMESQIVIM
                     MPLIEGLDGKEKMSKSLGNYIGIDEEAGIMYQKSMEIPDELIIKYYNLVTDVHPDEVN
                     KIESQLKEGSVNPRDIKMNLAREIVTLYHGEESAKEAEERFKSVFQKGQIPEDIQTIQ
                     VKEDGFDLIEVLVSNEIVKSKSEVRRLASQGGVKVNGEKVEDLSTIVKESELVVQIGK
                     KKFVKIELVK"
     misc_binding    complement(11082..11334)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(11486..12475)
                     /locus_tag="KR231_003074"
     CDS             complement(11486..12475)
                     /locus_tag="KR231_003074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2232 domain-containing protein"
                     /protein_id="HBH0005430.1"
                     /translation="MIYGGSVLNTTKKLTEAALLSSLFIVVTIIAVSTGFGYAIYLDF
                     IVPVFFCIICLKCDLKYTILSGITSLLIISLVLGNLGTAIWASQSVLLGIMCGYLINK
                     PTMVMDDLVYGSVFGVIVMVFIDIYASTLIGYSFMKEFQGYSKWIYFNGYTNFIYYLM
                     IALFPFGMVFCIYLLSLILGNKLHILDSNSLKKFLIFKNFRNLNQFLCCSKKAFYICV
                     SYLAIFEVLKLLNVKVDSVYLKTIFISITYISVYFIIRDSCMSLQNFIIAKFRKLLYA
                     RILFLIIILLLFFIFDVTVISLIIINAFLNKKINIRLSQSNIVNKQINLLIEK"
     gene            12627..13067
                     /locus_tag="KR231_003075"
     CDS             12627..13067
                     /locus_tag="KR231_003075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBH0005431.1"
                     /translation="MFKIKHFNDLSLDEFYEIAKSRYEVFACEQKIFSLNDYDDIDKS
                     SYHIFLKENGLICAYARIIPKEYSSYNDVSIGRVLVLSSHRRKGLAKQMMDCAIDFIK
                     VNLHENNITLSAQTYIKNLYLSCGFKEISEVYDEAGIEHIKMRL"
     gene            13394..13621
                     /locus_tag="KR231_003076"
     CDS             13394..13621
                     /locus_tag="KR231_003076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrous iron transport protein A"
                     /protein_id="HBH0005432.1"
                     /translation="MKNLNDIQVKKTVKVEDILSSGNLRERMLALGLTRGAVIDVVRK
                     GPKNNLTVYKIRGSKIALRQEESSLILVSDI"
     gene            13647..15767
                     /gene="feoB"
                     /locus_tag="KR231_003077"
     CDS             13647..15767
                     /gene="feoB"
                     /locus_tag="KR231_003077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrous iron transport protein B"
                     /protein_id="HBH0005433.1"
                     /translation="MGLTHNSTKMSSLKDMFDIDNKEDQFVIALAGNPNTGKSTVFNH
                     LTGLRQHTGNWPGKTVATARGNFKYKNTEYALIDLPGTYSLFALSQEEIVARDFICFG
                     NPDAVIVVCDATCLERNLNLVFQVMELTDKVILCINLIDEARKKGITIDKKLLEDSLG
                     IPVILTAARNGSGMDELLDTLNDVSFDKYKLNNKPVRYNENIENVVKSIQPELDNIIP
                     GINSRWLGLRLIDGDESIFESMSNYIDKDSIDAINEVKKKIPDNINKQKIRDEFTKIN
                     YDYAKKLSDECCSNVAKKSTDREEKVDKILTSKIFGLPIMLLLLGTILWITIEGANYP
                     STLLSNLLLGFEPSISGILNSINCPSWLNDMLVLGLYRTLAWVISVMLPPMAIFFPLF
                     TLLEDFGYLPRVAFNLDHLFKKACAHGKQCLTMCMGFGCNAAGVIGCRIIDSPRERLI
                     AILTNNFVPCNGRFPTLIAISTIFFSSVITNSFVSSVATALCITLLIILGVIITLLVS
                     YTLSKTLLKGVPSTFTLELPPYRVPQIGRTLYTSIIDRTIFVLGRAVMVAIPAGVITW
                     IFANIYIGDLSILSHVANFLDPLAKLIGLDGFILLAFILGFPANEIVVPILLMAYLAT
                     GSMIELDSFSALGQVLREHGWTYLTALNVMLFSLLHWPCATTLLTIKKETGSLKWTAL
                     GFLMPTILAFVVCFLTTTVYNLFI"
     gene            complement(15900..16718)
                     /locus_tag="KR231_003078"
     CDS             complement(15900..16718)
                     /locus_tag="KR231_003078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HBH0005434.1"
                     /translation="MEKQYFTTGEFAKLCGISKQTLIFYDKIGIFSPEYKDKNNYRYY
                     SVYQYDTLDILQSLREIGMSLEEIKEYIQNRTPQLCVKMLKEEEKKIREKIKKLRKIS
                     SKMQNRINITVEGISKMNSEEIYISKKFEEYLVLSSDLSNMSNSDFMMELIDFTNYCK
                     SKNLYQGYELGVIVSNENIKNGDYLSISSFYLKIDKKIKDKKLYVKPEGMYACIKHIG
                     KYEDSYKSYEKLKKYIYENEYKIVGNSYEESILDFFCESNEDNYMTEISIQVSR"
     gene            16925..>17149
                     /locus_tag="KR231_003079"
     CDS             16925..>17149
                     /locus_tag="KR231_003079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0005435.1"
                     /translation="MLVRVKIVIGATIRYLIKHKVNYCNKKSLDKLELKYGNIDREKA
                     VKLEIFYQYLIELEYIEMSLLIRRLDTAITS"
BASE COUNT         6037 a         2617 c         2239 g         6256 t
ORIGIN      
        1 aacaaagaga ttttaaatat gtgggtacat gatgtaaaga tacctatagc tataataaaa
       61 ctcattcttg aacaaaatga aaatttaatt gatgaaaaaa tttcagatga catagatagt
      121 gaaatattta gaattgaaaa ctccgttgaa aaaattttat atttatcaag actcgaagat
      181 tttcataagg attttttaat tcaagaggta aatattgaaa aaatcattag aaatattata
      241 aaaaaatact caaaatattt tatttcaaaa aaaattattt tagacttaaa taatttgaat
      301 tttaaggttt tatctgatga aaaatggcta tacttcatat tcgagcaatt attgagtaat
      361 tccctaaaat actcctcatt aggagataat atatctatct attgcaaaag aaccaaaaat
      421 tatttacaat taagagtgga agatactggt tgtggtataa aaaaggaaga tttaaatcga
      481 atattcaata agggatttac aggtaataat ggaagaaaca attctaaatc tacaggtctt
      541 gggctttatt tagtaaaaga actttgtgat aagcttggtc ataaaattga tgtagattca
      601 gagtacaacc aatatacaaa atttactatt acattcaaat gtgatttata gtatcttatt
      661 attgatagtt tattttcatt aacttatatt caacttctta tagtaattct atatgtacat
      721 cccagtatat aattaagtag tttttataaa aaggaggaag acatgtcttt tctaaaaaaa
      781 tttaaaaata aaagatttag aaataacagt tttaaaagta acaactttag aaatagcagt
      841 tttggaagta gtggcttcaa gtctaaaaat aaaggtttta aaaacaatcc ctttaaaaat
      901 aagagattca aaatatatgc aggaatagca gtaatcatac ttttaattct aggagttctt
      961 gcttatgttg attcgaaaaa cactgaatta caagctaatg aaaattttat cgaaacatat
     1021 actattcctg aaaatgaaaa aatatttata aatgggatgg ttgttcctaa gcaaactaag
     1081 gacttcaata tatctggaga ttatgagtta agtgatgtta atgttacaaa tggtcaaaaa
     1141 gtaaatcaag gagaccttct ttttactgct aaaaatccaa ctataatagc agaaatagat
     1201 agtttaaaat cacaacttag tcaatacaaa aaacaaaaaa tatcactttc tgatattgct
     1261 gaaaataaag atgctattgc ttctataaat gcacagataa ctgctttaaa ctctcagata
     1321 gcttctctgg ataaaaaagc ttatgacaga gttactgctc cttttgatgg cacagtatac
     1381 ttgaatgacc aaactggaaa tccagaccaa ccagtttcat ttatgactat tcaaggtcta
     1441 gagttttata tgaaaggaca agcaagtgaa caagatttac ctaaaatgaa gattgaccaa
     1501 atggtcaata tactagtttt ttcaactgac caaaagctta ctggtagaat aagttttata
     1561 tctgataaac catctactcc aaatactgaa atgggagctc agcagaatac actatcttat
     1621 tatgatataa acatagcatt tgataatcaa gaaggattag taaatggatt ccatcttcaa
     1681 gcatcacttg aagtagctaa ttcaagcttt aaaataccag catcttgtgt acttaaagac
     1741 aacaaacact catatgtatt taaggattta gatggtatat tgaaaaagca aattgtagat
     1801 gtagcaagtc aaaatgatga ttttgctgta gttagaggcg gtcttgaaca aggcgatata
     1861 ataataaaac accctactaa agaaatgaaa gaaggagacc cagttcaagg cgatggcgta
     1921 actgctggtt ctaataatgg agatactact ccaaacaaaa aagtagaaga agttactatg
     1981 gatgtgaatt aatttacata tgttaattaa attagaaaat attcaaaaat attacaaagt
     2041 agggaaagat gaattacatg ttttaaaatc cttaaattta gaaattgaat ctggagaatt
     2101 tgtcatgata atgggtaagt ctggtagtgg taaaactact ttacttaata tcttaggttt
     2161 tctagatgta tttgatgaag gaagatatat atttgatgga acagatgtaa ctaatttgag
     2221 tgaaaatgaa cgttctgttt ttagaaatat taatattgga tttgttttcc aacaatttaa
     2281 tttaatagaa actctaaatg tatatcaaaa tgtagagttg cctctaattt acaataaagc
     2341 actaaaaaaa tctaatagag aagaaattgt taaagataaa ttaagttctg ttgggctttt
     2401 ggacaagctt aagcagaaac cacttcaatt atctggtggt caacaacagc gtgtagccat
     2461 tgcacgttgc ctagcaaatg accctcagat aatctttgct gacgaaccga ctggggcatt
     2521 agatagtgaa actagcagag aaattatgga gcttttaaca aggctcaaca aacaaggtaa
     2581 gactataata atggttacac atgatcaaga tttaactaag tatgcaacta aggttatacg
     2641 acttaaagat ggtgtgttta cttcggaggt gtaatcatga gtttattaaa aaattctttg
     2701 gccaatttaa aaggtcacaa gcttcgtgta tttgtagctt tactctggat tataatagga
     2761 ataacttcag taatacttgt tagttctata ggtaatggat ttcaaaaaga aattaagaaa
     2821 tctgtaaaca atgtaaaccc taataaaact actatttcgt ttgaatcagc cgataacaca
     2881 ggtcttactg atgatatgag tattttttta aaacccttta atgcaaaaga tttagaagaa
     2941 ttatcatttg ttgaaggagt agaaagaata gctccttcaa gagatgggtt taaccttgat
     3001 tcagtttact cttcacaagc atcttttgat aaaaaaacta cgtatgttga tgttggacca
     3061 gtaaaaaaag attctaaaat aaatttaatt tgtggtagag atttttcttt agatgatgaa
     3121 aaaagaaaag taattttact tacattacaa agtacaagtg aaatttttga aaatccagaa
     3181 gatgccttag gtcatggtat caacataaat ggaactatat ttgaaataat aggggtatta
     3241 gatgattctc agcaaaacca agctggagga ttctttggag gttaccaaga tatgcaattt
     3301 actacttccc tagtacctaa aaaggctttt gacactttaa tgagtcaaaa ttcttattca
     3361 aatgaaattt accagttaga cttagtttct tctaaaggct ataatgtaaa tgaagttgca
     3421 aacaatgtta tagctaaatt atatgagatg caccctggta tcaatggttc ttatactaca
     3481 ccagacccaa ctgaacagac agcttatctt gaaagcatta attccaatgt aaacaaatat
     3541 gtatctataa taactgtagt tgcaatgttt gttggtggta ttggtgtaat gaatataatg
     3601 tatgtatctg ttatggaaag acaaagagaa attggtataa gacgtgctat tggagcaaaa
     3661 cctaggtcta tattatttca atttttagtt gaagctgttt ttataacagt atgtggtgga
     3721 attttaggaa ctatagttgg atttgctgct actaactatg tttctaaata tataggtttt
     3781 gaagctatac ctagcttaaa tagcttattt tatgcaattg tagctactat attgactgga
     3841 gttgtatttg gtctgattcc agcctttaaa gcttctaaac tagaccctat aaaggcaatt
     3901 tataagtaga aattgtataa agattttcga tttttagatt agtttatata aaacatactt
     3961 aaatatataa cgcactatta tatatgatag attaggaact taatctttcc aaatataata
     4021 gtgcgttctt tcataaaaag gattctcttc cttactatat ctaaattacc aagatgttat
     4081 gttctaattg ttcaaactaa tacttccaat tttgattaat caatctcatt ctcctaatat
     4141 acaatctttt actttcaatc attgtacact ccgccttaaa aaaataatct taaattaggc
     4201 gttatataca atctccccat tacatattgt ataattaacc tttccatata aagatttacc
     4261 tttaaatggt gaattatcag ctttagaaac aaagctttca actgtccatt cttcttctgg
     4321 attgaatata acaatgtctg ctacagcccc ttcttctata aatccaatat ttaaattgta
     4381 caattttgca ggatttatag acattttttc tattaactgc atcatactaa gatgattttt
     4441 atgcaccaaa tttgttattc caagagctaa agaagtttca agcccaataa ttccacttgg
     4501 agcttttata aactctctat ctttttcttc tttactatga ggtgcatggt ctgttgctat
     4561 tatttcaata gtaccatcat ttaatccctc tataatctta tctctgtccc atttacttct
     4621 tagaggtgga ttcatttttg catttgttcc aaactccaat acatcttcct cagtcaatgt
     4681 aaagtgatgt ggtgaagctt ctgcaactac atttgcacct aagtattttg caaatctaac
     4741 catatcaaca gatacacctg aacttatatg ttgtatatca actttagcac cagtctttag
     4801 tgccaacata caatctctgg ctaccataac atcttctgct acacttgatg caccttttaa
     4861 tccaagttct gaagctacct ttcctgcatt tacacctgga tttccaacta aagaagggtc
     4921 ttcttcatga aaactaagtg gtacatccaa ctcttttgcc ttaatcattg cctccataat
     4981 tagattgcta tccattaaag gtaatccatc atcagtaaac cctggtacac cagctttttt
     5041 aagagcttcc atatcaacta actctttacc ttcaaaacct ttagttatag ctgctgcttg
     5101 taaaacattt atacatgcat tttttgactt ttctttaaca taattaaaag tatcttcatt
     5161 atctacaata ggattagtat ttgccataca tataacagtt gtaaatccac ctctagcagc
     5221 agatttagct ccactttcta tatcttcttt atatgtaaac ccagggtctc taaagtgtac
     5281 atgtacatcc actaaacctg gagcaactac attaccacta gcatctatta ttttttcata
     5341 ttcatcactt tcatcaaact tgcctatttt ataaatttta ttttctttta taattaagtc
     5401 aatattctca tctctttgac ttttagggtc tattactcta ccatttttaa ttaaaatcat
     5461 attatttctc ctttatattt ttaatttata tagactcata taatattata cattatttta
     5521 catacttaaa tacaaaatta cgtttgacat caatagcctt tttaggacaa agttcatggc
     5581 aacagtaaca tcttatacat ttacttaagt ctataatagc acccttagtc cctatctcta
     5641 tagtggatgc aggacaagct tccttgcatt ttccacattt tatgcaatct tgaaatctta
     5701 ccacaggctt tggtgttata agctttgaaa taggttcatt taaaaatttt ggtagcttta
     5761 cggaaaacaa tcttaaatct ttacttacat ttggaatctt gtaatttttt ataattaaat
     5821 cttttatatc ttcacctaaa atttcaatat ctgaaaaatc ttcttgtata tatcctctct
     5881 taatagcacc tctaattgta gcaactttat ttggaagtaa acttataatc ttacatgcaa
     5941 caacatctat agcatatgga ttttgtgatg ctaataaaac tcctatttct cgagtagtac
     6001 cagctgaagg tccatcacct tccataccta ctataccatc cataattgtc aatgttggtt
     6061 ttatataatc acaaatatct aaaagtacat tttcgcaaaa caactcttct gtaggaaatc
     6121 tataatgtat ctctgctttt ttcaatccag ctatgcatcc atataagttt tttgtaccac
     6181 cagtaaaagt tgccattata tgagtcttta atttacaaag atttattata taatctgaat
     6241 ctactattgg tttaataata tccatatatt ttagaacatg tgctttttca ctatgtatct
     6301 taacatctga aacatcataa tttaacttaa tgcccagttc atttgctact tcttcaattc
     6361 cagatgcctt ataaatgctc ttaagagaac tttgattata tggaccacca gggctatctg
     6421 ctattgtaat atcacaattt aactctaaaa gtttttcaca tacaactttt acaaccatag
     6481 gatgtgtagt tgtagcttct tcaggctttt ttttcattaa taaatttggt tttataagta
     6541 ctttgcttcc ttttttaaca aacttatcta taccaccaat atcctctaaa tttttttcaa
     6601 tagataactt tacttcttca taattgtaag ttttacaact cctaacagat accgacttca
     6661 tattatctcc atccttctat cacaacagtt tatttatata atttaaaaaa ggagaaacca
     6721 aagtttctcc ttttaatcta tgttttaatt gttttaatta ttattttcca aaatgtctgt
     6781 ttaataatcc taagaatgct ttaccatgtc tagcttcgtc tttacacatt tcatgtactg
     6841 tatcatgtat agcatctaat cctaattctt tagctctctt agctaatttt aattttccat
     6901 cagttgcacc atactcagca tcaactctaa ctcttaagtt ttcttttgta tctgcaacta
     6961 caacttctcc aagaagttct gcaaatttag cagcatgttc agcctcttca aaagctattc
     7021 tcttatacgc ttcagctact tctggataac cttctctatc agcttgtcta ctcattgcta
     7081 aatacattcc tacttctgta cactcaccag taaagttagc tcttaatcct tcgattattt
     7141 ctgcatctac accttgagct actcctattc tatgttcatc agcccaaacc atttcgcctt
     7201 tcatttcttc aaatttatca gctccaactt tacatactgg acattgtgct ggtgcagcat
     7261 ctccttcatg tatatatcca catactgtac aaacaaattt tttcataatt aatttcctcc
     7321 caattttata taattaaatt tttattttta agtttaataa cttgctacaa gaatatatat
     7381 accccagact ttatagctta aacactaaaa ataaaattta tttcctaatt aattttatca
     7441 ctttgaaaca ccagtatcaa ccaagttttg atgtcaaatt tctacataat acataattta
     7501 tttgattaat taggaaatag ttgtcatatt aaatactttc taatgaagac tcctctgaat
     7561 ctttaagttt cacttttttg ctctttaaaa aagataattt agtttctgca gttatgattg
     7621 caacaaatat caagatacta ccaataacca attttgctgt aataagctcc tttaaaatta
     7681 ttatagaaaa tattgtacca aatacagcct ctgtggataa tattatagct gttctagttc
     7741 catcaactct tttttgacat atagtctgaa ataaaaatcc aattgtagta ctaaatacag
     7801 ctagatacat agttcccatg taaccagata attcagcttc catctttaat tgacctgcaa
     7861 atgtttgaac tacaacagac attaaaaacg ctactgtaaa ttgaatagct gtcaatgcca
     7921 ttgggttgtt atcttttgca aactcacttg taaagaatat atgaaatgca aatccgaatg
     7981 aacatataag tgttagaaaa tctccaaaat taatagagaa atcagcttct aaagaaagta
     8041 tcccaattcc tataagagct accaaactac ttattattcc tattttatca agttttcttc
     8101 tataaagtat aaatcctatg aatggaacta ttacaacatt agctgctgtt ataaacgcat
     8161 ttttagatgg tgtagtgtac ataagtccaa tagtttgtac tgtgaatgct agaaataaaa
     8221 atattcctaa aatccctcct gcttttaata attttttacc catattggca cgaatctgtt
     8281 taaaaaacag taaattcata attatagctg ccaagaaaaa tcttaaagtt atgatttgta
     8341 gaggtgtaag cccaccgtct aatgcaaatt gggttgctac aaagccactt ccccatataa
     8401 ttgctataaa tattagtcct atttctccaa agtatttttt caataaagct ccctcctttt
     8461 tatttttttg caaaattata aaccccctaa acagcaagag agtttttcta taagcattac
     8521 tataaattaa tatagtaaat tttttcagta ttttaaatct aaatttacat acattttgag
     8581 ctcaaattta tatccactat ttaacagtaa tatattaatc attttttgta aacacctttt
     8641 taataaattt ttatattttt tatatttttt tacctatact aaattttttt atagatattt
     8701 ttaatatata tgatacttta atattatgca aataatgtca tataagttac actttagtta
     8761 tcttagttac aactttgtcg gtttactttt tctactttct tcgatataat tataatatat
     8821 ttttgataca attcgacaaa agggggaatg ctgtaattat ggtaaaaaaa agaaaaaaga
     8881 aaactgttac acttactata cttgttgtaa tagttattgg tattttttct atggcatggg
     8941 cggacatgtc tagaaaaaaa gaaatgaaag aaactcaaga aagacttaaa gctgaaagat
     9001 tagaaaaaga aagaattgaa aaagaaaaaa atgaacctat tattggtgca aaaaaagaag
     9061 ctgtaaaaga atatggatat gacgcaaaaa tagtttggga caaacttaac aaatacgact
     9121 attcaaacaa tggagaaaag atagtctttc ttacatttga tgatggacca tctactacta
     9181 atactccaca agttctagat atcttgaaaa gacatggtgt tagaggaact ttctttatta
     9241 agggtgattc tcttgaaaga aaaggagcta atgaaatttt aaaaagaaca tttgacgaag
     9301 gaaatgcaat agcccatcac tcttatactc atgactataa aaaactatat cctaacagaa
     9361 gcctaaatct cgatacattc gtaaatgaac ttaacaaaac tgatgaagct atgaaaaaag
     9421 tcttaggaaa gaatttttcc tcaaatgtag ttagatgccc aggcgggtac atgtcatgga
     9481 aaaatatgga acctctagga aactacttaa aagagaaaaa catggcatca attgattgga
     9541 acgctttaaa tgctgatgca gaaggtaaaa agaaaaatgc acaagaatta tttgaacatg
     9601 caaagaaatc ttctgaaggc aaagaaatgg ttgttctttt aatgcatgat acttatggaa
     9661 aacaagaaac agtaaatgca ttggaccaaa ttataacata ttttaaagac aatggttatc
     9721 aatttaaaat tttaatataa taaaaaagca agtttattga atgtacattt tatactcaat
     9781 agacttgctt ttactttact ctattttact agctcgattt ttacaaattt tttctttcct
     9841 atttgaacaa ctaattcact ctcttttaca atagtgctta aatcctctac tttttcacca
     9901 tttaccttta ctccaccttg agaagctaat cttctaactt cactcttact cttaacaatc
     9961 tcattagaaa ctagtacttc gattaagtca aatccatctt ccttaacttg aattgtttgt
    10021 atatcttcag gtatttgacc tttttggaat acagatttaa atctttcttc agcttcttta
    10081 gcagattctt ctccatggta taatgttact atttctcttg ctaagttcat ctttatatct
    10141 cttggattta ctgaaccctc tttcaactga gattctattt tattaacttc atcaggatga
    10201 acatctgtca ctaaattgta gtatttaatt ataagttcat caggaatttc catagatttt
    10261 tggtacatta ttcccgcttc ttcatctatt ccaatatagt tacctaaact cttactcatt
    10321 ttttctttac catctaatcc ttctattaaa ggcatcatta ttactatttg agactccata
    10381 ccaaattctc tttgtaatga tcttcccatt agtaaattga atctttggtc agttccacca
    10441 agttctatat cagcttctaa tgctatagag tcatatgctt gcattaatgg gtagaagaac
    10501 tcatgtactg atattggcat ttgtccttca tatctctttt taaaatcttc tctttctaac
    10561 attctcgcaa cagtaatagt tgctgctaat tttattacat cttcaaaatt taacttagct
    10621 aaccactcgc tattaaatct tacaatagtt ttttctttat ctaaaacttt gaaaatttgt
    10681 tcttcataag tttttgcatt tgcaagaact tgctctgttg ttaaagcttt tctagcttta
    10741 gattttccag ttgggtctcc aatttttcct gtaaaatctc caattattat tactatttga
    10801 tgacctaaat cttgtaattg tttcatcttt ctaagaacta ctgtatgccc taaatgtata
    10861 tctggagcac ttgggtctag acccaatttt actatcatag gctttccttc tttttctgat
    10921 ttaataagct tttcccttaa ctctttctca tctattaaat catctacacc tttcataatt
    10981 attcgcattt gctcgtctat cgatttcatt tttcattcct cctaaaatat ttatataatc
    11041 tataattttt atttttataa taaaaaaagc tttcatcctc ttaaaaggac gaaagcattg
    11101 cttacgtgtt accaccttag ttcatcaata tctcacgata ttaatctctt agagtacaat
    11161 tacatatact cgtgtactat aacgtgtact aatccgatat ctcttaatgg ttgttatctt
    11221 tcagagatag tgctctgaga tgtattcaaa ctaaatcaat ttattccatt tcaccaaact
    11281 ggaactctct gttaaataaa atctagccct acttcttctc ttcatagcat ttatatattc
    11341 agattatttc atcaattaca agaaattttt cttaacttac tcataatata ttattatttt
    11401 tatattttgt caaccttttt tattattata tacatgtttt tttacattat actacttttt
    11461 tatatttttt accaataccc aaaatttatt tttcaatcaa aagatttatt tgtttattga
    11521 ctatattact ctgactcaat cttatattta ttttcttatt taaaaatgcg tttataatta
    11581 ttaaactaat aactgttaca tcaaatataa aaaacagcaa taaaattatt atcaaaaata
    11641 aaattctagc atataataat tttctaaact tagctattat aaagttttgt agtgacatac
    11701 atgagtctct aatgataaaa tagacactta tataggttat tgatataaag attgttttta
    11761 aataaacaga atcaacttta acattcaaca gttttagaac ttcaaaaatg gctagataag
    11821 aaacacatat gtaaaaagct ttttttgagc aacataaaaa ttggtttaaa tttctaaagt
    11881 tcttaaatat taaaaatttt tttaaagaat tagaatctaa aatatgcaat ttattcccta
    11941 aaattaaact taataaatat atgcaaaaca ccataccaaa aggaaacaat gctatcatta
    12001 aataataaat aaaatttgta tacccattaa aataaatcca tttgctatat ccttgaaatt
    12061 ctttcataaa actataacct attaatgttg aagcatatat atcaatgaaa accattacaa
    12121 taaccccaaa tactgaacca tatactaaat catccataac cattgtaggc ttatttatta
    12181 gatagccaca cattatacca agtaatacac tctgacttgc ccaaatagca gttcctagat
    12241 ttccaagtac cagagaaatt attaaaagcg aagtaattcc agataaaatg gtatacttta
    12301 aatcacattt caagcagatt atacaaaaaa atactggcac tataaaatct aagtaaatag
    12361 catatccaaa tccagtactc acagctataa ttgttactac tatgaataaa gatgacaata
    12421 aagctgcttc agttaatttt ttagtagtat tcaaaacact gcctccataa atcataaatt
    12481 ttctaactaa agttttgttt ttaatatagt atatcacttt ttaaaaatat ttttaataaa
    12541 tataaatttt aataaaggta tttatgttaa aaatggtata atgtatctta atattcagtt
    12601 ttttaagatg ctaggaggta attactatgt ttaaaattaa acactttaat gatttgagtt
    12661 tagatgaatt ttatgaaata gcaaaatcaa gatatgaggt atttgcttgt gaacagaaga
    12721 tattttcatt aaacgattat gatgatatag ataaaagctc ttatcacata tttttaaaag
    12781 aaaatggatt gatttgtgct tacgctagaa taattcctaa agaatacagc tcttataatg
    12841 atgtttccat tggtagagtt ttagttcttt ctagtcatag aagaaaagga ttagcaaaac
    12901 aaatgatgga ttgtgctata gattttataa aagttaactt acacgaaaat aatataacct
    12961 tatcagcaca aacttatata aagaaccttt acttatcttg tggttttaaa gaaatctcag
    13021 aagtatacga cgaagcaggt attgaacata ttaaaatgag attatagtgt tgacaagcta
    13081 atattgttaa tatataattt aagtataaat taaatattga attgatattt aggtatttga
    13141 aaatacctta catagagtca gaaggctttt gctttctgac ttttttatta tcaaaattca
    13201 ataattatat ggattcaaag tgttaatttt tattctatat tctactttcc ccaaaagtaa
    13261 gaattatacc caactttgta tgataggcat cttgcctatc ttttttttgt aaaagtaaca
    13321 aggtaataat ataatgcata gtttaaaata agaagattag cccaggctaa atttcaagca
    13381 tggaggtgct attatgaaaa accttaacga tattcaagtg aaaaaaactg tcaaagttga
    13441 agatatatta tctagtggta atttaagaga aagaatgtta gcgcttggtc ttactagagg
    13501 agctgttata gatgtagtta gaaaaggtcc aaaaaataat ttaactgtct ataaaatcag
    13561 aggtagcaag atagctctac gacaagaaga aagtagctta atattagttt ctgacattta
    13621 aaaatttcta gcaggaggat attaatatgg ggttgacaca taactcaact aaaatgagtt
    13681 ctttaaaaga catgtttgat atagacaata aggaagacca gtttgtaatt gcattggctg
    13741 gcaatccaaa tacaggtaaa agtactgtat ttaatcatct tacaggactt agacagcata
    13801 ctggaaactg gccaggaaaa actgtagcta cagctcgtgg taattttaaa tataaaaata
    13861 ccgaatatgc attaatagat ttaccaggaa catattcttt atttgcctta tcacaagaag
    13921 aaattgtagc tcgtgatttt atatgttttg gtaatccaga tgcagtaata gtagtatgtg
    13981 atgctacatg tcttgaaaga aatttaaatt tagtatttca agtgatggaa cttacagata
    14041 aagttatttt gtgtattaat ttaatagatg aagctagaaa aaaaggcatt actattgata
    14101 aaaaactttt agaggattct cttggtattc cagttatttt aactgctgca agaaatggct
    14161 ctggtatgga tgaactattg gatactttaa atgatgtatc ttttgacaaa tataaattaa
    14221 ataataaacc tgttagatac aatgaaaata tagagaatgt ggtaaaatca attcaaccag
    14281 aattggataa tattatacca ggtataaatt ctagatggtt gggacttaga cttattgatg
    14341 gcgatgaaag tatatttgaa tctatgagta attatataga caaagattct atagatgcta
    14401 ttaatgaagt aaagaaaaag attccagaca atataaataa acagaaaata agagatgagt
    14461 ttactaaaat caactatgat tatgctaaaa aactgagtga tgagtgttgt tctaatgttg
    14521 ctaaaaaatc aactgataga gaagaaaaag tagataaaat attaacatct aaaatatttg
    14581 ggcttccaat aatgctctta ttattaggta ctatattgtg gattactata gaaggagcta
    14641 actatccatc cactttatta tctaatttat tactcggatt tgagccaagt atttcgggta
    14701 tattaaatag tattaattgt ccatcatggt taaatgatat gttggtttta ggattataca
    14761 gaacattagc atgggtaatc tctgtaatgc tacctcctat ggcaatattt tttccattat
    14821 ttaccctact tgaggatttt ggatatttgc caagagttgc atttaactta gaccacctat
    14881 ttaaaaaagc ttgtgcacat ggaaaacagt gtttgactat gtgtatggga tttggatgta
    14941 atgcagctgg agttattggt tgtaggataa ttgactctcc aagggaaaga cttatagcta
    15001 tacttacaaa caactttgtt ccttgtaatg gtcgttttcc tactttgata gctatatcta
    15061 caatattttt tagctcagtt ataaccaact ctttcgtatc aagcgtagca actgcacttt
    15121 gcataacttt actgataatt ctaggtgtta taataacatt gttggtttct tatactcttt
    15181 ctaaaacgct attaaaagga gttccgtcta catttacatt agaacttcct ccttatagag
    15241 ttcctcaaat aggaagaact ttatatacct ctataataga tagaacaata tttgttttag
    15301 gaagggctgt aatggtagcc atacctgctg gtgtcataac ttggatattt gcaaatatat
    15361 atataggaga tttaagtata ttatcacatg ttgcaaactt tttagaccct ttagctaaat
    15421 taattggtct tgatggtttt atattacttg cttttattct tggattccca gcaaatgaga
    15481 tagttgtacc tatactttta atggcttacc tagcaactgg ttctatgata gaattagata
    15541 gctttagtgc tttaggtcaa gttcttagag aacatggatg gacttatttg acagctttaa
    15601 atgttatgct gttcagttta ctgcattggc cttgtgcaac aacactttta acaataaaaa
    15661 aagaaactgg tagtttaaaa tggactgcct taggattctt aatgcctact atacttgctt
    15721 ttgttgtttg ttttttaaca actacagttt acaatttatt tatataatta gtattaactg
    15781 acagtagaca tatattagag aaaccattta aaaatttata tactttatta taaagcatag
    15841 agatatattc aatgataagt aaaattactt aacatttgaa tatatctcta ttttaattct
    15901 tatctggata cttggattga aatttcagtc atataattat cttcattact ttcacaaaaa
    15961 aagtcaagta tactctcctc atacgaattt ccaacaattt tatattcatt ttcatatata
    16021 tattttttca atttttcgta agatttatat gaatcctcat attttccaat atgttttatg
    16081 caagcataca ttccttctgg ctttacatat agctttttat cctttatttt tttatctatc
    16141 ttcaaataaa aacttgatat acttaaatag tccccatttt ttatattttc attacttact
    16201 attactccca actcatatcc ttgatacaaa tttttcgatt tacaataatt ggtaaaatct
    16261 attaattcca tcataaaatc actattactc atattactca aatcgcttga tagaactaaa
    16321 tattcttcaa actttttgga tatataaatt tcttcactat tcattttaga aattccttca
    16381 actgttatat ttattctatt ttgcatctta gaacttatct ttcttagttt ttttattttt
    16441 tctcttatct ttttttcttc ttctttaagc attttcacac aaagctgggg agttctattt
    16501 tgtatatact cttttatttc ctctaaactc attcctattt ctcttaatga ttgtaatata
    16561 tcaagtgtat catattgata aactgagtaa tatctataat tatttttatc tttatattca
    16621 ggagaaaaaa tacctatttt gtcatagaaa attaatgtct gcttagatat accacacaat
    16681 ttagcaaatt cacctgttgt aaaatactgt ttttccaagg gttatacact ccttttcttt
    16741 ttgttgtcta tatagttact atattcttta ttatttacta aatcaagtag ttattatttt
    16801 agaaaatcaa tatggttttg attttaaagc ttaaatatca gttagatgtc agttataaat
    16861 attttaccca ttcccatcat aaaaaagata tcccctctta acttttggat ggaatattat
    16921 atttatactt gttagagtga aaattgtaat aggtgctaca ataagatatt taattaaaca
    16981 taaagttaat tattgtaata aaaaatcttt agataaatta gagttaaagt atggaaatat
    17041 agatagagaa aaagctgtta aactagaaat attttatcaa tatttaatag aacttgaata
    17101 tatagaaatg agtttattaa taagaagatt agatactgca ataacatca
//
LOCUS       DAEPHU010000082        16945 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 01A10CD0081
            SAMN05941466-rid12468953.denovo.082, whole genome shotgun sequence.
ACCESSION   DAEPHU010000082 DAEPHU010000000
VERSION     DAEPHU010000082.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941466
            Sequence Read Archive: SRR6291087
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 16945)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16945)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068158.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 22:43:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,892
            CDSs (total)                      :: 3,805
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 87
            rRNAs                             :: 8, 1, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 55
            CDSs (without protein)            :: 55
            Pseudo Genes (ambiguous residues) :: 0 of 55
            Pseudo Genes (frameshifted)       :: 21 of 55
            Pseudo Genes (incomplete)         :: 28 of 55
            Pseudo Genes (internal stop)      :: 16 of 55
            Pseudo Genes (multiple problems)  :: 8 of 55
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16945
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941466-rid12468953.denovo.082"
                     /strain="01A10CD0081"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            56..367
                     /locus_tag="KR231_003080"
     CDS             56..367
                     /locus_tag="KR231_003080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GIY-YIG nuclease family protein"
                     /protein_id="HBH0005436.1"
                     /translation="MYFTYIIRCKDDSLYTGYTSNIVRRMNEHKLGINSKYTRAKGFE
                     KLEVYFVTNTKSNAMKLEYYIKKLTRNKKLSIIKNPSILINLIDNKEDYIIGKEIEQL
                     T"
     regulatory      460..552
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            652..1446
                     /gene="thiD"
                     /locus_tag="KR231_003081"
     CDS             652..1446
                     /gene="thiD"
                     /locus_tag="KR231_003081"
                     /EC_number="2.7.1.49"
                     /EC_number="2.7.4.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional hydroxymethylpyrimidine
                     kinase/phosphomethylpyrimidine kinase"
                     /protein_id="HBH0005437.1"
                     /translation="MSNYKIPTLTIAGSDSSGGAGIQADLKTFSAIGTYGMSVITAIT
                     AQNTKGVFAVEDLNKKIIKKQIEAVFEDIPPRAVKIGMVSSPEIILEIVENLKKYNPK
                     YLVVDPVMISKSGYYLLKPEAKENLIKYLIPLAYIITPNIPEAEEITGIKIHNVDDMK
                     RVGEEILQLGPKFVLMKGGHLDGEAVDILVGKNIFKVYKSERIDKKNTHGTGCTLSSA
                     ITSYLALGYEITEAVNLSKIYITEAIKRSFDIGHGVGPVHHFYKFE"
     gene            1470..2258
                     /gene="thiM"
                     /locus_tag="KR231_003082"
     CDS             1470..2258
                     /gene="thiM"
                     /locus_tag="KR231_003082"
                     /EC_number="2.7.1.50"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxyethylthiazole kinase"
                     /protein_id="HBH0005438.1"
                     /translation="MYNLIKDVKKLNPLVIHYTNNVTINDCANVTLAVGASPLMSFSY
                     EEVEEMVSVANSVVINIGTMNSNMLDLFLLAGKAANKYNKPVVLDPVGVFASKARAEL
                     TSRLLNEVKFSVVKGNVSEIKFIGGFNVRGKGVDSFDEEEDSTEIIRKIAEKLECVVV
                     ATGKIDIITNGKGTYKINNGTDKLKGITGTGCMTASLIASFMAVTENILEAATMGVLT
                     MSLSGELANLNNPPIGTFKENLMNAIYQMDIDTLSKNSNIEFLN"
     gene            2281..2913
                     /gene="thiE"
                     /locus_tag="KR231_003083"
     CDS             2281..2913
                     /gene="thiE"
                     /locus_tag="KR231_003083"
                     /EC_number="2.5.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine phosphate synthase"
                     /protein_id="HBH0005439.1"
                     /translation="MIDKESLKKCLKLYLVTDSEMLKGRDFYKCLEDAISSGITTVQL
                     REKNASGREFLRKAMKLREITKQYGVKFIINDRVDIALICDADGVHVGQSDIDVREVR
                     KLIGNNKILGVSARTLEEAICAKNDGADYLGVGSIFTTSTKLDAKSASFETVKEIKEK
                     VDMPFVLIGGINLDNIDKLKCLESDGYAIISAILKAEDISKEVEKWTLKI"
     gene            3052..3354
                     /locus_tag="KR231_003084"
     CDS             3052..3354
                     /locus_tag="KR231_003084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436486.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBH0005440.1"
                     /translation="MIRILLVCVGGMSSTLLVNKMEKDAKKRNIDCKIWAVGEGDIKS
                     ELDNFDILLLGPQLRFMLDDVKSIVGDRAPVSIIDMVNYGTCNGHAVLNSVLEILK"
     gene            complement(3420..4169)
                     /locus_tag="KR231_003085"
     CDS             complement(3420..4169)
                     /locus_tag="KR231_003085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBH0005441.1"
                     /translation="MLNILWRSMKWRFKNPISFVVTILQPFLWLVLYSSIANQTMNNI
                     NINNYTAFILPGIIVLVVFSSCSSGGIINFIMKNSGSFYRVLIAPISRYSIVLGQLLE
                     AILVSFIEVTILCIVSIFFSVRIESGIGGILLMIVLIFMTAFFLSSLAYSISLLLPNE
                     IVYETIMTAIVLPIFFLSSALFPIESLSGGLKVAVMLNPFTHVINALRSLIFGETILI
                     GDILPVILLFLILCCSSFSLAMWRLKKEMVS"
     gene            complement(4163..5125)
                     /locus_tag="KR231_003086"
     CDS             complement(4163..5125)
                     /locus_tag="KR231_003086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH0005442.1"
                     /translation="MLAIEIDNLVKEYKNGVKALNGLSFNVNAGEIFSLLGPNGAGKS
                     SLINILTTFYKPTSGNVTMFGKDLVDNPSWIRTQIACVAQQISIDEHLSLMENMVFQS
                     KMYKVEPQIAKQRIDSLIDKFDLSSYLKYPTSSYSGGVKRRLDIAMNMVSSPKILFLD
                     EPTVGMDVDSRKSMWDMLLKIRDEYGTTIFLTTHYLEEAEQLSDNICIMKNGKDLAQG
                     TPSSLRSYIRQNILRITFHNTEDIKKYKDSIKSTGLVKFMSVRENSIFISVNDSRTAF
                     TLINKWLLEHDIEFDAIEIVEPSLEDVFLALTSSKKSLKEEWEC"
     gene            complement(5129..5587)
                     /locus_tag="KR231_003087"
     CDS             complement(5129..5587)
                     /locus_tag="KR231_003087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GyrI-like domain-containing protein"
                     /protein_id="HBH0005443.1"
                     /translation="MNCKIEIKNIESVTVATMRYNGPMTEATKYFPNVFKAIKGKSNG
                     APFFCYYDVDQKTGVAEMELCVPTAETPNRMGITTKEFPKTKALFFTHTGSYSNLPKT
                     YEMIFKYIHENNIKIQTPWREVFIKGPGMLIKGNPDNYITEIIFPLKEEE"
     gene            5943..6299
                     /locus_tag="KR231_003088"
     CDS             5943..6299
                     /locus_tag="KR231_003088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBH0005444.1"
                     /translation="MNFELDNTTPIYLQIVKYIKRQIVTGELKPGETIPSRREMALNL
                     KVNLNTVQRAYKEMGDMNIINTFKNYQSSVTVDENILKNLKLELINESLSVFIEDMKA
                     INVSKEEVLKIIEDKY"
     gene            6371..7087
                     /locus_tag="KR231_003089"
     CDS             6371..7087
                     /locus_tag="KR231_003089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH0005445.1"
                     /translation="MIEIKNVSKTYKRMQGLKIRKIEALKNVSFNIEKGKITALLGIN
                     GVGKSTMLKAIAGLINIDSGEIRIDGEKINEKVYNKLAFVPDVQSHFSNTTIKETFEF
                     MEIFYSKWNKEKSKEMMDIFKLDEDEIIDNLSKGNIARVKLILGFCQDPEYILLDEPF
                     TGIDLFKREEFIGVIAQYMEENQAIIITTHEIVEIESLVDEVVILDEGQIITSFNAEE
                     LREREGKSILDKMREVYKNE"
     gene            7080..7904
                     /locus_tag="KR231_003090"
     CDS             7080..7904
                     /locus_tag="KR231_003090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBH0005446.1"
                     /translation="MNKLLYLINVDLRRSNKFYIAYISFFSLITLSLNLFEINKFKNS
                     KFIMNLAIEDFGGIFYGLGILSNLGFIQSILFFGILGLFIYYVFMWKREFFSNNQSIY
                     TLMMLPQNKFKICISKSIALITMIYGFLISQTATLFICKYIFNFIFRNMPIINMNFAK
                     DLYYLNLKSIPIDFISFMAIYVFLLLIAISIVNCCILFIFSYINKFYVILITLLIIAG
                     LYFSTIYINIITLFRKYYNLIGFQFNNLVAGLLSFLIIMFILNGISYLLIKKKVSL"
     gene            7916..9115
                     /locus_tag="KR231_003091"
     CDS             7916..9115
                     /locus_tag="KR231_003091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0005447.1"
                     /translation="MKLKSKISILIIFLTLAIYFSIGLLNNEDNLKIKTIKGDSNELD
                     HININFGYALNGYINSYYTINGSNKTKKTELIKLQKDSKNTNNLIDVSSGSDLIAHVG
                     FEMNEESKDINFVIDEKKEDLEKGVFPSEDSDKEIEYEKLDMNNFTRTRYKVDKSTDD
                     YYAKILSSKRYKKYLYVSVLYATSDSSENNKEYSSTIDIIKINPENKKIKTIKSINLS
                     NYFSEKYQNIENIGVSYASKYEDKMYILVNVLNTNIGDNSNSKFHLLEYNLEENKESI
                     MELKTDSKMALAKAKLEANKLYMVMSNDYDNSSITELNLLTYNILDKSLDEDKYVLDN
                     REKRGIRSIEIDSNKIVAYTSRLNSILSWDDKFMLYIINKNSKEIVYEGELQFNSSNS
                     MLEFEIK"
     gene            9124..9936
                     /locus_tag="KR231_003092"
     CDS             9124..9936
                     /locus_tag="KR231_003092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0005448.1"
                     /translation="MKDLIRLFEFELKRNIKNYIFIIICCCSFVILNIVKNLNDYNYI
                     IENAVKSEQLTKIGNTIETVNVTGFSSFRNIMGSTELWFMFGIIACICYAFFIWYRDF
                     NGRSKSIYTLIMLPKNRINIYISKLLNILFLVYSYTVVLTISLFIASKLLPRHMLGNV
                     TNYGFVQETIYELKMLLPYSFEILFVEYIFLLIGFVSVVFTSILINKSIYKVSTLISF
                     LFLVIEILVFIISIEFIIPYEYSDVFTVLYSSINIFVCSLISNKLLKQKIDF"
     gene            9947..11215
                     /locus_tag="KR231_003093"
     CDS             9947..11215
                     /locus_tag="KR231_003093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0005449.1"
                     /translation="MKAKNIGKYTICFIIVCFLMITMTLILSYFNKDKLSVKTLKGNV
                     KDIGRVSVVYTPNISKFSYEEVIISKNGVRNNTNPKSRIRNDYLNIDKKYSDFVNDKG
                     KEFIYKDDLNIGEAYTSVKSDLVQGMNALNDCIKVSNKNLKSGVEENFDINLNKSDFK
                     ENSWKTLFNKIYKGNLYMVISETNISGSKVNNICILKIDIKNKSYKLLNRFNLGLQNG
                     EQQNINEIKFSIGSKLYLEIVNNKSKNGYIEGHDSYSNFIIYDIEDNTFNISNKFMNN
                     LNKEKNANPKEIGLLSKTKLDYMVKNNKLNLIVTDMSNSITNLVYDINSNEIKLEDYE
                     ILDLKVDYNEASSGVRKVKLLDDKIYSISGIKNSISGELKGFKGIVDVVGTKPVKFQV
                     FDMKLKKNIYEAELINGDISLQEKLFFVAN"
     gene            11581..12762
                     /locus_tag="KR231_003094"
     CDS             11581..12762
                     /locus_tag="KR231_003094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase family protein"
                     /protein_id="HBH0005450.1"
                     /translation="MNKKYIKAGNLIDGTGNSIMQNKGIIIDGDTIVEIEDIRDDLNG
                     YDVYDYLDKTVMPGIMNCHVHLTMEPVGNPKIYYDNVSDVELVVNTIKQLDAYLDSGV
                     TYIRSLGCPKYVDVQLKNLIDKGSIDGPGIVTSGPVICMTGGHGYYFGIESDGVDECR
                     KSARTVLKNGVDCVKIMATGGVTTDGVEPGSPQLTLEEMKAAVDEAIKAGKITATHAQ
                     GRTGIKNAVLAGITSIEHGVYLDDEIIDLMLERGTYLVPTVAAPYFILNAGKESGITE
                     ATLRKCEIVAIPHKESFLKAYKKGIKIAVGSDAGTSYNEHGKTYYEMKLMSDYGMDNM
                     DIIVAATKTASELLRIDKNYGTLEKGKKADVIVVNGNPVENIDVLADVLAVFKLGKKV
                     R"
     gene            complement(12904..13821)
                     /locus_tag="KR231_003095"
     CDS             complement(12904..13821)
                     /locus_tag="KR231_003095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436448.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0005451.1"
                     /translation="MENNKCREDFRFTQEYEEDYPNTNERYYENYQVADRYYNYPNKY
                     KEPKIKQCCCKKSMREALELLRYDALRPFVNFNQFAFISDFFIVGANLVGIDLSAPPK
                     DNLSGLDGTFERFSACNCDLIDIAGRVSYPIPVPLTLEGLINTIGTIPGVAELIALID
                     AVIPPTIDLGAILDAILAAIIDFILAASTPLANVDLASLCNLKAVAFDITPADYEDFI
                     ASLGYYLDKKHYKECNCNCDCDDCCCNKGILDNLYMSNINNQVTVVAGSLVLTGVEVL
                     GKKNDVIVLGNSNDSRIYFVCVDSIDYIA"
     gene            14074..14868
                     /locus_tag="KR231_003096"
     CDS             14074..14868
                     /locus_tag="KR231_003096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH0005452.1"
                     /translation="MIEVDKLCKSFTRVVKDDKNKSSIRKLKKVKTKKEEFFAVNNVS
                     FKVMEGEIVGILGPNGAGKTTLLRMLGGILTPTSGSINISGYDYSIDRNSAKKEIGYL
                     SGNTKLYGRLSPRELLTTFASLYEMSKEDIEESIENIVKIMDMSEFIDNRIENLSTGQ
                     TQRTSIARCLIHSPKVYIFDEPTLGLDVLSSASIIDFMKNEKLRGKTVLYSTHYMEEA
                     ETLCDKIFMIHNGKIIASGTPQSLKEESGVNNLRDVFIKLARKEDI"
     gene            14869..16929
                     /locus_tag="KR231_003097"
     CDS             14869..16929
                     /locus_tag="KR231_003097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HBH0005453.1"
                     /translation="MRSKIVKYIFKKEMLDILRDKKTLFMMIVVPLLLYPLLMLLMIQ
                     VMNMSASSMNSKDINIAFNNKPNKVLVSMIEDDNLEKDTKNTSNDKGKIRVLDVDNYK
                     KSLEENKIDAYIKMEEKKSSINYQIYINSSQENSSNALKRIETVLDKYKRFTIEKTLS
                     EKGLDVQATLEPITYSTVDVAKTEEVAGYFLGQILPFILIIGVLLGSIYPAIDVMAGE
                     KERGTLETLFTLPISNLELVMGKYMAVSLSAIVTAILNILSMGLTMAFILVSGGISSQ
                     FGFGNFNYGDLVLPIITTLICICLFSMVVSAISMCVCSLAKSFKDAQNYITPLMLIIM
                     IPSYVSMIPNIVLDRVTAVIPVVNISLLIKSVLSFKSDLNLIALVLASNVAFVILAII
                     LLSKMFNSEEILFSNSKSFSFLEKRSNIKKGSIPTVSDGVILYAVGLVLLIYVGSLVQ
                     IKFGMAGIIMTQFMIISLPLLFAYYIKADFKEVFSLKVPKLKHVFGSIVLWIGGYILI
                     MIITQLILFLFPQNMEVAESLNKALFIKDSVLLNLLAIALLPALCEEMFFRGFIFSSF
                     SKSKDKNKSIKLAIICSGVLFGIMHMDFIRIIPTSILGIIFAYSVYKSGSIFVSMLLH
                     FLNNSVAVVLNHYTTGNITNLYKFVEVDFSNLNVLKFALILLISLILIMLGLRVLDRK
                     SLRN"
BASE COUNT         6686 a         1809 c         2713 g         5737 t
ORIGIN      
        1 ttttttaatt ctataatata atatttatat atttaatgtt aggatgtgat ttaaggtgta
       61 ttttacatat attataagat gtaaagatga ttctctatac actggatata ccagtaatat
      121 agttagaaga atgaatgaac ataaattagg aattaattca aaatacacaa gagcaaaggg
      181 atttgaaaaa ctagaagttt attttgtgac caacacaaaa agcaatgcta tgaagttaga
      241 atattatata aaaaaattaa ctagaaataa aaaattgtct ataataaaaa acccaagtat
      301 acttataaat ttaattgata ataaagaaga ttatattatt ggtaaggaaa tagaacaatt
      361 aacataaata tttatagtaa cattataatg ggtgcatatg gtgtaaaaac ttgacaataa
      421 atactattgt aatataatga agttataaat atagtaaatt aaaatagcta ggggagccaa
      481 gagctgagag gtataccgac ccttacacct gatctggata ataccagcgt aggaaagctt
      541 agtaaaaatt caagtatgta ttatttgtga tatatgctat ttctaagcta tacctattgt
      601 aggtatagct tttttaatta agttatttaa attaaacttt aggaggcaac aatgagtaat
      661 tataaaatac caacacttac aatagccggc tctgattcat ctggaggagc tgggattcag
      721 gctgatttga aaacgtttag tgcaattggt acttatggta tgagtgtaat aacagctata
      781 acagcacaga atactaaagg agtttttgct gtagaggatt taaataagaa aataataaaa
      841 aaacaaatag aggcagtctt tgaagatata cctccaagag ctgtaaaaat aggaatggtt
      901 tcaagtcctg agattatact tgaaatagtt gagaatctaa agaaatacaa tccaaaatat
      961 ttggttgtgg acccagtaat gatatctaaa agtggatatt atctattaaa gccagaggca
     1021 aaagaaaact taattaagta tttgatacca cttgcataca taattacacc aaatatacca
     1081 gaggcagaag aaataacagg aataaaaata cataatgtag atgatatgaa gagagtagga
     1141 gaagaaatac tacaacttgg acctaaattt gtacttatga aagggggtca tttagatgga
     1201 gaagcagtgg atattttagt tggtaaaaat atatttaaag tttataaaag tgaaagaatt
     1261 gataaaaaaa atacacatgg aacagggtgc acattatctt ctgcaataac atcttatcta
     1321 gcattaggat atgaaataac agaagcagta aatctaagta aaatctatat aacagaagca
     1381 ataaaaagaa gttttgatat aggtcatgga gtaggaccag tacatcattt ttataaattt
     1441 gagtaataaa aaaatattgg aggtagaata tgtataattt aattaaagat gtaaaaaaat
     1501 taaatccatt ggtaattcat tatactaata atgtaactat aaatgattgt gctaatgtaa
     1561 ctttagctgt aggagcaagt cctcttatga gtttttcata tgaggaagta gaagaaatgg
     1621 taagtgtagc aaactctgta gtaataaata taggaactat gaactcaaat atgttggatt
     1681 tattcctatt agctggaaaa gcagcaaata agtacaataa acctgttgtt ttggacccag
     1741 ttggagtatt tgcaagcaaa gcgagagcag aacttacaag tagactttta aatgaagtca
     1801 aatttagtgt tgttaaaggg aatgtatcag aaataaagtt tataggtggc tttaatgtaa
     1861 ggggtaaagg tgtagattca tttgatgaag aagaagattc tactgagata ataagaaaga
     1921 ttgctgaaaa gcttgaatgt gtagttgtag caactggaaa aatagatata ataactaatg
     1981 gtaaaggtac atataaaata aacaatggaa ctgataaatt aaaaggaatt acaggaactg
     2041 gatgtatgac tgctagcttg attgcaagtt ttatggctgt tactgagaat atattagaag
     2101 cagcaacaat gggtgttctt acaatgtctt taagtgggga attagctaat ttaaataatc
     2161 caccaatagg tacatttaaa gaaaatctta tgaatgctat ttatcaaatg gatatagata
     2221 ctttaagtaa aaattctaat attgaatttt taaattaata aagagtaagg gagacttaaa
     2281 atgattgata aagaatcttt aaaaaaatgt ttaaagttgt atttagtaac tgactctgaa
     2341 atgcttaaag gtagagactt ttataaatgt cttgaagatg caatatcttc tggaataaca
     2401 actgtacaac ttagagaaaa aaatgcttct ggaagagagt ttttaagaaa agctatgaaa
     2461 cttagagaaa taactaaaca atatggtgtt aagtttataa taaatgatag agtggatata
     2521 gcacttattt gtgatgcaga tggagtacat gtaggacaga gtgacattga tgttagagag
     2581 gttagaaagc ttataggaaa caataaaatt ctaggagtat cagcaagaac tttagaagaa
     2641 gctatttgtg caaaaaatga tggcgcagac tatttaggtg tagggtctat attcacaaca
     2701 tctactaaat tagatgcaaa atcagcttcg tttgaaactg ttaaagaaat taaagaaaaa
     2761 gtagacatgc catttgtact aattggaggt ataaatttag acaatataga taaacttaaa
     2821 tgtttagaaa gtgacgggta tgctataata tcagctatat taaaagctga agatatctct
     2881 aaagaagtgg aaaagtggac attaaaaata taaaattggc tctggtagtg aaaaaaatgg
     2941 aaaaatttga tataatctaa gagtaaaatt taagcaatta taaatgataa acttttctac
     3001 atatactttt taatcaagat atatgtagat ttggttaaaa aggagctata aatgattagg
     3061 atattgttag tgtgtgttgg aggcatgtct tctaccctat tggtaaataa aatggagaag
     3121 gatgcaaaaa aaagaaatat agactgtaaa atatgggcag ttggagaagg agatataaaa
     3181 tcggagcttg ataactttga tattttactt cttggaccac aacttagatt tatgcttgat
     3241 gacgtaaagt ctatagttgg agatagagct ccagtatcta taatagatat ggtaaactat
     3301 ggcacttgta atggtcatgc tgtgttaaat tcggttttag aaatattaaa ataaataata
     3361 aaagtggatt ctatataata gagtccattt ttattatttg ttattaatag gcttaaaact
     3421 tagcttacca tttctttttt taatctccac atagcaagtg aaaaacttga acagcacaat
     3481 attaaaaata gtaggataac aggcagtata tctccaataa gaatagtctc accaaatatt
     3541 aagctacgta aagcgttaat aacatgggta aatggattga gcatcactgc tacttttaat
     3601 cctccagata aactttctat agggaaaaga gctgaactta aaaagaaaat aggaagtaca
     3661 attgcagtca taattgtttc ataaactatt tcatttggca ataataaact tatagaataa
     3721 gctagacttg ataaaaagaa ggctgtcata aatatcagta ctatcataag taggattcca
     3781 ccaatgccag attctatcct tactgagaag aatatactta ctatacacaa aatagttact
     3841 tctatgaaag aaactaagat agcttctaat aattgaccaa ggacgattga atacctactg
     3901 ataggtgcaa ttaagactct atagaaactt ccactgttct tcattataaa gtttataata
     3961 ccaccactac tacaagaaga aaacacaacc agtacaatga tacctggtag tataaaagca
     4021 gtataattat tgatatttat attattcata gtttggtttg caatagaact ataaagcaca
     4081 agccaaagaa aaggttgtaa tatagtaact acaaatgaga ttggattttt aaaacgccac
     4141 ttcatactac gccataagat atttaacatt cccattcctc ctttaagctt tttttagaac
     4201 ttgtaagtgc taaaaataca tcttcgagac ttggctctac aatttctatt gcatcaaatt
     4261 ctatatcatg ttctaaaagc catttattta ttaaagtaaa agcagttcta ctatcgttta
     4321 cacttataaa aattgaattt tctcgtacgc tcataaactt tactaaacca gtacttttaa
     4381 ttgaatcttt atattttttt atatcttcag tattatgaaa agttatacgt agtatatttt
     4441 gtctaatgta actacgtaaa cttgatggtg ttccttgtgc taaatccttt ccattcttca
     4501 taatacaaat attatcactc aattgttcag cttcttcaag ataatgagta gttagaaata
     4561 tagttgtgcc atactcatct ctaattttta ataacatatc ccacatagat tttcttgaat
     4621 cgacatccat accaacagtt ggttcatcta aaaataggat tttaggagat gataccatat
     4681 tcatagctat gtccaatcta cgttttacac cccctgaata tgatgaagta ggatatttta
     4741 agtaactaga taagtcaaac ttatcaatta aagagtctat tctttgtttt gcaatctgtg
     4801 gttctacttt atacatttta ctttgaaata ccatattttc cataagggat aaatgttcat
     4861 caatagagat ttgctgtgct acacaagcaa tttgagtacg tatccaagaa ggattatcta
     4921 ctaaatcttt tccaaacatt gttacatttc cagatgtagg tttgtaaaag gtagtcaaaa
     4981 tatttataag agaagattta ccagcaccat taggaccaag taaagaaaaa atttctccag
     5041 catttacatt aaagcttaga ccatttaaag ctttcacacc atttttatat tcttttacta
     5101 aattgtctat ttcaatcgct aacatatatt attcctcctc tttaagtgga aatattatct
     5161 ctgtaatata gttatctggg tttcctttta tcaacatacc tggtccttta ataaatactt
     5221 ctctccaagg agtttgtatt tttatattat tttcatgaat atatttaaat atcatttcat
     5281 acgtttttgg caaattacta taagagcctg tgtgagtaaa aaataaagct tttgttttag
     5341 gaaattcttt tgtagttata cccatacgat ttggagtttc agcagttgga acacataatt
     5401 ccatttctgc aacaccagtt ttttggtcaa catcatagta gcaaaagaat ggtgcaccgt
     5461 tagactttcc ttttatagct ttaaatacat ttggaaaata ctttgttgcc tcagtcatag
     5521 gtccattata acgcatggta gccactgtga ctgattcgat atttttgatt tcaattttgc
     5581 aattcatttg tttacctcct aatgtgtgtt catattctta ctagattttt aagcattaat
     5641 acatataaga ttttgattag ttgaaaacat ataatcttat ctcgtttgct tgttttcaag
     5701 tctaacataa cataaaatat atatcctctc atttgatgct ccattttgta aagttattat
     5761 ttaagcttta ctttagattt tttagcaaat taaaataaag caatttataa aataagtatt
     5821 tacaaattaa gtgtattaat cgtataatac acttaatagg atactagata aagtctgaaa
     5881 taaaggcgta tttttttaaa gtaagtgtac tatcgtatta atacactaga ataggaggaa
     5941 tcatgaattt tgaattagat aatacaactc ccatttattt gcaaatagta aagtatataa
     6001 agagacaaat agtaacagga gagttgaaac caggagagac aataccatca agaagagaaa
     6061 tggcacttaa tctaaaagta aacttaaata cagttcaaag agcatataag gagatgggtg
     6121 atatgaatat aataaatact tttaaaaatt atcaaagcag tgtaacagtt gatgaaaata
     6181 tattaaaaaa tttaaaatta gagcttataa atgaatcact atctgttttt atagaagata
     6241 tgaaagcaat aaatgttagc aaagaagaag ttttaaaaat aatagaagat aagtattagt
     6301 tttttaacaa atagaaaact tagtttagaa agtttattta taagcatatt ggatgtggag
     6361 gatagtaaat atgatagaaa taaagaatgt cagcaaaaca tataaaagga tgcaagggct
     6421 taaaataaga aagatagaag ctttaaaaaa tgtaagtttt aatatagaaa agggaaaaat
     6481 aactgcatta cttggtataa atggtgttgg taaatcaact atgttaaaag caatagcagg
     6541 acttataaac attgatagtg gagaaattcg tatagatgga gaaaaaataa atgaaaaagt
     6601 atacaataaa ttggcttttg ttccagatgt acaatctcac tttagcaata caacaataaa
     6661 agaaacattt gaatttatgg aaatttttta ttcaaagtgg aataaagaaa aatcaaaaga
     6721 aatgatggac atatttaaat tggatgaaga tgaaataatt gataacttgt caaaaggaaa
     6781 cattgcaaga gtaaaattaa tacttggatt ttgccaagac ccagagtaca tacttcttga
     6841 tgaaccattt acaggaattg atttgtttaa gagggaagag tttataggag taatagcgca
     6901 atatatggag gaaaatcaag ccattatcat aactactcat gagatagtag agatagaaag
     6961 tttagttgat gaggttgtaa ttcttgatga agggcagatt ataacttcat ttaatgcaga
     7021 agaattaaga gaaagagaag gtaaatctat attagataag atgagggagg tatataagaa
     7081 tgaataaact tctatatcta ataaatgtag atttgagaag aagcaataag ttttatatag
     7141 cttatatatc atttttttca ttaattacac ttagtttaaa tttattcgaa attaataaat
     7201 ttaaaaattc taaatttatt atgaacttag caatagaaga ttttggaggt atattttatg
     7261 gactagggat acttagtaat cttggtttta tccaaagtat attgttcttt gggatattgg
     7321 gactttttat atactatgtt tttatgtgga aaagagagtt cttttcaaat aatcaaagta
     7381 tttatacact tatgatgtta cctcaaaata agtttaagat ttgtatatct aaatcaatag
     7441 ccttgataac aatgatatat ggttttttga taagtcagac agcaacatta tttatatgta
     7501 aatatatatt taatttcatt tttagaaata tgcctataat caatatgaac tttgccaaag
     7561 atttatatta tttaaacttg aagagtatac caattgattt tatctctttt atggctattt
     7621 atgtattttt actacttata gctatttcta ttgtaaattg ctgtatatta tttatctttt
     7681 cctatataaa taaattttat gtaattttaa tcactttgct gattatagca ggcttatatt
     7741 tttcaacaat atatataaat ataatcactt tatttagaaa atattataat cttataggat
     7801 ttcaatttaa caatttagta gcagggttat taagtttttt aattataatg tttattctaa
     7861 atggaatatc ttatttgcta attaaaaaga aagtatctct ttaaggaggg gtggtatgaa
     7921 attaaaatct aaaatatcta tacttattat atttttgact ttagcaatat attttagtat
     7981 aggtttatta aataatgaag ataatttaaa gataaaaact ataaaaggtg actctaatga
     8041 attagaccat ataaacataa attttggata tgctttgaat ggatatataa attcatatta
     8101 tacaataaat ggaagcaaca aaactaaaaa gactgaatta ataaaactac aaaaggatag
     8161 taagaacaca aataatttaa ttgatgtatc tagtggttca gatttaattg ctcatgttgg
     8221 atttgaaatg aatgaggagt caaaagatat aaactttgtg atagatgaga aaaaagaaga
     8281 tttagaaaaa ggtgtatttc catcagaaga tagtgataaa gaaattgaat atgaaaaatt
     8341 agatatgaat aattttacaa ggacaagata taaagtagat aaaagtacag atgattatta
     8401 tgcaaagata ctatcatcaa aaagatataa aaaatactta tatgtatctg tactttatgc
     8461 tacaagtgat tcatcagaaa ataacaaaga atattcaagt actatagata taataaaaat
     8521 taatccagaa aataaaaaaa tcaagactat aaaaagtata aatttaagta attatttttc
     8581 cgaaaaatac caaaacatag agaacatagg tgtaagttat gctagcaaat atgaggataa
     8641 gatgtatatt ttagtaaatg tactaaatac aaacataggt gataatagta attctaaatt
     8701 tcatttactt gagtataatc ttgaagaaaa taaggaaagc ataatggaat taaaaactga
     8761 tagcaaaatg gctttagcaa aagcaaagtt agaagctaat aaattatata tggtaatgtc
     8821 gaatgattat gataatagtt caattacaga gttaaattta cttacctata atatattaga
     8881 taaaagctta gatgaagata aatatgtttt agataataga gaaaaaagag gaattagaag
     8941 tattgaaatt gattcaaata aaatcgttgc atatacatca aggctaaact ctatattatc
     9001 ttgggatgat aaatttatgc tatatataat aaataaaaat tctaaggaaa ttgtatatga
     9061 aggagaatta caatttaaca gttcaaatag tatgttagaa tttgaaataa agtaggtgag
     9121 ttgatgaaag atttaataag attattcgaa tttgaattaa aaagaaatat aaagaattat
     9181 atatttataa taatttgttg ttgttctttt gtaattttaa acatagtaaa aaatttaaat
     9241 gactataatt acataataga aaatgcagtt aaaagtgaac agttaacaaa aatcggaaat
     9301 acgatagaaa cggtaaatgt tacaggtttc tcaagcttta gaaatataat gggttctaca
     9361 gaattgtggt ttatgtttgg tataattgca tgtatttgct atgctttttt tatttggtat
     9421 agagacttta atggtagaag taaatctata tatacactta taatgctacc taaaaataga
     9481 atcaatattt atatatctaa attattaaat atattatttc tagtgtatag ctatacagta
     9541 gtacttacaa tatctttgtt tattgcaagt aagttgttac ctagacatat gcttggtaat
     9601 gtcacaaact atggttttgt acaagaaaca atatatgagt taaaaatgtt acttccatat
     9661 agctttgaaa tactatttgt agagtatata tttttattga taggatttgt atctgtagta
     9721 tttacatcaa ttcttataaa taaatctatt tataaagtaa gcactttaat aagttttcta
     9781 tttttagtta tagaaatttt agtgtttata atttctatag aatttattat accttacgaa
     9841 tacagtgatg tatttactgt tctatattca agtataaaca tatttgtatg tagtcttata
     9901 tctaataaac ttttgaagca aaagattgac ttttaggagg gatattatga aagcaaaaaa
     9961 tataggaaaa tatacaatat gttttataat agtatgtttt ttaatgatta ctatgacctt
    10021 aatattgagt tattttaata aggataaact atctgtaaaa actttaaaag gcaatgtaaa
    10081 agatataggg agagtaagtg tagtatatac acctaatata agcaaatttt cttatgagga
    10141 ggtaattata agtaaaaatg gagtaagaaa taatacaaac ccaaaatcaa gaattagaaa
    10201 tgattattta aatattgaca aaaaatacag tgactttgtt aatgataaag gaaaagaatt
    10261 tatatataaa gatgatttga atataggaga agcgtatacc tctgttaagt ctgatttagt
    10321 acaaggaatg aatgctttaa atgattgtat aaaggtttca aataaaaatt taaaaagtgg
    10381 ggtagaagaa aattttgata ttaatttaaa taagtctgat tttaaagaaa atagttggaa
    10441 aaccttattt aacaaaatat ataaaggtaa tttatatatg gtaattagtg aaactaatat
    10501 ttcaggttct aaagtcaata atatttgtat attaaagata gatataaaaa ataagtctta
    10561 taaattatta aatagattta atttaggatt acagaatgga gaacaacaaa atatcaatga
    10621 aattaaattt tctattggaa gtaaattata cttagaaata gtaaataata aaagtaaaaa
    10681 tggatatatt gaaggacatg atagttactc taactttatt atatatgata tagaagataa
    10741 cacttttaat ataagtaata aatttatgaa taatctaaac aaagaaaaga atgcaaatcc
    10801 aaaggagatt ggcttattaa gtaaaactaa gctagattat atggtaaaaa acaataaatt
    10861 gaatcttata gttacggata tgagtaattc cataactaat cttgtttatg atattaattc
    10921 taatgagatt aaattagaag attatgagat acttgattta aaagtagatt ataatgaagc
    10981 atcatctgga gttaggaaag ttaagctact ggatgataag atatattcta tttcaggtat
    11041 taagaacagt atatcaggag aattaaaagg atttaaaggg attgttgatg tagtcggaac
    11101 taagccagta aaatttcaag tatttgatat gaaacttaaa aagaatattt atgaagctga
    11161 gctaataaat ggagatataa gtttacaaga aaagttattt tttgttgcaa attaagtgtt
    11221 agaattaatt ttagaacttt aaacttttat atgtatcaca gataagtata agtaagggag
    11281 tgtctcaaaa taaacttttt agctcatgag acactttttt tatatgaaat caaatatatt
    11341 ttcattgttt agatttattt tgataatgaa aaaaagatta tctttatttt aagaaagaca
    11401 tttatttata attatataca aaaatatttt ttaatgtttt tgtgtataat tataacaatt
    11461 taatttatat taatgcactt aaatttgaaa tagaatgctt atagtggtaa aattaattat
    11521 tagaatatta gaaataataa ataaataata cattgtactt aaaaggggga gaaatttaag
    11581 atgaacaaaa aatatattaa agcagggaat ttaattgatg gaaccggaaa tagtattatg
    11641 caaaataagg gtataattat tgatggagat actatagttg aaattgaaga tataagagat
    11701 gatttaaatg gatatgatgt gtacgattac ttagataaaa ctgttatgcc aggcattatg
    11761 aattgtcatg ttcacttgac aatggagcca gttggaaatc caaagatata ttatgataat
    11821 gtatcagatg tagagcttgt agtaaatacg ataaaacaac ttgatgctta tttggattca
    11881 ggagtaacat atattagaag cttaggttgt cccaaatatg tggatgtaca acttaaaaat
    11941 cttatagaca aagggtctat agatggtcct ggtatagtta cttcaggtcc agttatatgt
    12001 atgacaggag ggcatggata ttattttggt attgaaagtg atggagtgga tgaatgtaga
    12061 aaatcagcca gaacagtttt aaaaaatgga gtagattgtg taaagataat ggcaactgga
    12121 ggtgtaacaa ctgatggagt tgagccaggg tcaccacaat taactttgga ggaaatgaag
    12181 gctgctgtag atgaagctat aaaagcaggt aaaataactg ccacacatgc acaaggaaga
    12241 actggtataa aaaatgcagt gcttgcagga attacttcta tagaacatgg tgtttattta
    12301 gatgatgaaa taattgattt gatgcttgaa agaggaactt acttagttcc aactgtggct
    12361 gcaccatatt ttattctaaa tgcaggaaaa gaaagtggaa taactgaagc tactcttaga
    12421 aagtgtgaga ttgttgccat tccacataaa gagtcattcc taaaagcata taaaaaagga
    12481 attaaaattg cagttggttc tgatgcagga acttcttata atgaacatgg aaaaacatat
    12541 tatgaaatga aactaatgtc agattatggt atggataata tggatataat agttgctgct
    12601 acaaaaacag catctgaact tttaagaatt gataaaaatt atggaactct agaaaaagga
    12661 aagaaagcag atgttatagt tgtaaatgga aatccagtag agaatataga cgtacttgca
    12721 gatgtgttag cagtatttaa acttggtaaa aaagttagat aaatagtata aaaataaaaa
    12781 agagtgtcta aagaaatttt taaataatta tagacactct tttttattag taataattaa
    12841 atcttttata ctttagaaaa tagattctat tttatattta gatataactc tttaaaatca
    12901 ttcttatgca atataatcta tagaatctac acatacaaag tatattcttg aatcattaga
    12961 atttccaagt actataacat catttttctt acctagaact tcaacaccag ttagaaccaa
    13021 actaccagct actacagtaa cttgattatt tatatttgac atataaagat tatctaggat
    13081 acctttatta caacagcaat catcacaatc gcagttgcaa ttacattctt tgtaatgttt
    13141 tttatcaaga tagtaaccta aagatgctat gaaatcttca taatctgcag gtgtaatatc
    13201 aaatgcaaca gctttaagat tacacaatga tgctaaatct acgtttgcta atggagtaga
    13261 tgcagcaagt ataaaatcaa ttatagcagc aagtattgca tctaatatag ccccaaggtc
    13321 tatcgtagga ggaataactg catcaataag tgcaattaat tcagctactc ctggtatagt
    13381 tcctatagta ttaattaatc cctcaagagt taaagggact ggaataggat aagatactct
    13441 accagctata tctattaaat cacagttaca agcagaaaat ctttcaaaag taccatcaag
    13501 tccagataaa ttatcttttg gaggagctga aagatctata cctaccaaat tagcacctac
    13561 tataaagaaa tctgagataa aagcaaattg attaaagttt acaaaaggtc ttagagcatc
    13621 atatcttaga agttctaatg cttctctcat acttttttta caacaacatt gttttatttt
    13681 aggttcttta tatttatttg gataattata gtatctatca gctacttgat aattttcata
    13741 gtatctttca tttgtatttg gataatcttc ctcatattct tgtgtaaatc taaagtcctc
    13801 tctacattta ttattttcca ctaaatacac tccttttata ttttaattta aatgtataga
    13861 taattaagct tatctatata gtaatattat atttataatg taaaaaaatg ttacaaaaga
    13921 tattataaac gaataaaaaa taataatttg ccagataaac ttgtaaattt ttatgaataa
    13981 tccattctaa aacaaaaaac tgtgtataaa aaaggtttat atgttatatt tatataaata
    14041 taacatatga acgagaaagg agtggtttga taaatgattg aggtagataa attgtgtaag
    14101 tcttttacaa gggttgtaaa agatgataag aataaaagtt caataagaaa gctaaagaaa
    14161 gtaaaaacta aaaaagaaga attttttgct gtaaataatg tttcatttaa agttatggaa
    14221 ggtgaaattg ttggaatatt aggtccaaat ggtgcaggaa agactacatt acttagaatg
    14281 ttaggtggca tattaacacc aacatcagga agtataaata tttctggata tgattattca
    14341 atagatagaa attcagcaaa aaaagaaata ggttatctct ctggaaatac aaaactatat
    14401 ggaaggcttt ctccgagaga acttctaaca acttttgcaa gtctatatga gatgtcaaaa
    14461 gaagatatag aagaatcaat tgaaaatatt gtaaaaataa tggatatgag tgaatttata
    14521 gataatagaa ttgaaaatct atcaactggt cagactcaaa gaacatctat agctcgttgt
    14581 ttaatacatt ctccaaaagt atatattttt gatgagccaa cactaggtct ggatgtttta
    14641 agtagtgcat ctattataga ttttatgaag aatgaaaaac taaggggaaa aactgttctt
    14701 tactcaactc attatatgga agaagcagaa actttatgtg acaagatttt tatgattcac
    14761 aatgggaaaa taattgcatc aggaacacca cagagtttaa aagaggaatc tggagtaaat
    14821 aatttgagag atgtattcat aaaacttgcc agaaaggagg acatttaaat gagaagtaag
    14881 attgtaaaat acatatttaa aaaagaaatg ttagacatat tgagagataa aaagacttta
    14941 tttatgatga ttgttgtgcc acttctttta tatcctttac ttatgttatt aatgattcaa
    15001 gtaatgaata tgtctgcaag tagtatgaat agtaaggaca ttaatatagc ttttaataat
    15061 aaacctaata aggttttagt atccatgatt gaagatgata atttagaaaa agatactaaa
    15121 aatacttcaa atgataaagg caaaataaga gtgttagatg tagataacta taaaaagtca
    15181 ttagaagaaa ataaaattga tgcttatata aagatggaag aaaaaaaatc atctataaat
    15241 tatcaaatat atataaattc ttctcaagaa aattcttcta atgcactaaa aagaattgaa
    15301 actgttttgg ataaatataa aagatttacc atagaaaaaa ctttatctga aaaaggatta
    15361 gatgtacaag ctactttaga accaataaca tatagcactg tagatgttgc aaagacggaa
    15421 gaagtggcag gatacttttt aggtcagata cttccattta tattaataat aggagtttta
    15481 ctaggttcaa tatatccagc aatagatgtt atggctggag aaaaggaaag aggtacatta
    15541 gaaacattat ttacactgcc aatatcaaac ttagaactgg ttatgggaaa atatatggca
    15601 gtttctctta gtgcaatagt aacagcaatt ttaaacattt tatctatggg actgactatg
    15661 gcatttattt tagttagtgg aggtattagt agccaatttg gctttggaaa ctttaattat
    15721 ggagacttag tcttaccaat tataactact ttaatttgca tatgtctttt ttcaatggta
    15781 gtttcagcaa taagtatgtg tgtatgttca ttagcaaaaa gttttaaaga tgctcaaaac
    15841 tacataacac ctcttatgtt aattattatg ataccatcat atgtttctat gataccaaat
    15901 atagtattag atagagtgac agctgtaata cctgtagtaa atatatcttt acttataaaa
    15961 agtgtattat cttttaaaag cgatttaaat ttaatagcct tagttttagc atcaaatgta
    16021 gcctttgtta tattggcaat catactactg tctaagatgt tcaattctga ggaaatactt
    16081 tttagtaata gtaagagttt ctctttctta gagaaaagaa gtaatataaa aaaagggtct
    16141 ataccaactg taagtgatgg tgttatttta tatgcagtag gattagttct attgatttat
    16201 gttggttctt tagttcaaat taaatttggt atggcaggta ttataatgac acaattcatg
    16261 ataatttctt taccgttatt atttgcatac tatattaaag ctgattttaa agaggtattt
    16321 agcttgaaag ttcccaaatt aaagcatgtg tttgggagca ttgttctttg gattggtgga
    16381 tacatactta ttatgattat aacacagcta attttattct tatttcctca aaatatggaa
    16441 gttgctgaaa gtttaaataa ggctcttttt atcaaagata gtgttttact gaatttacta
    16501 gcaatagctt tattaccagc tttatgtgaa gaaatgtttt ttaggggatt tatattttct
    16561 tcatttagta aatcaaaaga taaaaataag tctatcaagc tagctataat atgcagtggg
    16621 gtactatttg gtattatgca tatggatttt attagaataa ttccaacatc aatattaggt
    16681 attatatttg catatagtgt gtataaatct ggttcaatat ttgtatcaat gttattgcat
    16741 tttttaaata atagtgtagc agttgtgtta aatcattata caactggaaa tataaccaac
    16801 ttatataaat ttgttgaagt tgatttttcg aacttaaatg tacttaaatt tgccttaatt
    16861 cttctaataa gtcttatatt aattatgtta ggattaagag ttttagatag aaagtcttta
    16921 agaaattaag tataaagtta ttata
//
LOCUS       DAEPHU010000083        16749 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 01A10CD0081
            SAMN05941466-rid12468953.denovo.083, whole genome shotgun sequence.
ACCESSION   DAEPHU010000083 DAEPHU010000000
VERSION     DAEPHU010000083.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941466
            Sequence Read Archive: SRR6291087
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 16749)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16749)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068158.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 22:43:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,892
            CDSs (total)                      :: 3,805
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 87
            rRNAs                             :: 8, 1, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 55
            CDSs (without protein)            :: 55
            Pseudo Genes (ambiguous residues) :: 0 of 55
            Pseudo Genes (frameshifted)       :: 21 of 55
            Pseudo Genes (incomplete)         :: 28 of 55
            Pseudo Genes (internal stop)      :: 16 of 55
            Pseudo Genes (multiple problems)  :: 8 of 55
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16749
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941466-rid12468953.denovo.083"
                     /strain="01A10CD0081"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            330..2189
                     /locus_tag="KR231_003098"
     CDS             330..2189
                     /locus_tag="KR231_003098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EAL domain-containing protein"
                     /protein_id="HBH0005454.1"
                     /translation="MKRFLRRIILVLFILLIFISFISIKLIHNVGDYGKLINYVGIVR
                     GASQRLTKLEMNHQPNDELIEYIDEILQELITGHGDYGLVITDCNEYNEDLLLLEKKW
                     EDLNIEIKKVRMKEQNNQLLSISEEFFSLANDTVFKIENFSKEKSNYLMTLIIIISII
                     GILACIILILQYSKKMVRLEKLNVDLKNIAYKDELTGVNTIEKFKLDANQNICIHKDK
                     KFAVFYIDFENFKYINDIFGYDYGDMILKRYANLMMNDIGKYEIFAREIADRFVALRC
                     YVDKEDLVVRQRDVDNELINITNEIKNKHSITVVSGICCIEDVNEKLSIDGLINRANF
                     AQKTVKNKPGTNYAFYNDSIRKKMIEENTIKSRIHEAIEKREFIVYLQPKVNLHSQKI
                     NCAEALVRWLTPDKGIISPAIFIPVLEKNFFIALVDKYVFEEVCKWIRKRLDENKPFV
                     QISVNVSRIQFYNTKFVETYSNIQNKYRIPKNTIEIEFTESVAFENQKHLLEIIHDLH
                     ENGFTCSLDDFGKGYSSLSVLKDLPFDVLKLDSMFFKASLDKDKEKIVIKNIVHMLKE
                     LNITTVAEGIECKEQVEFLRDIGCDLVQGFVFYKPMPILEFEKILDKEFVYNS"
     gene            complement(2481..3080)
                     /locus_tag="KR231_003099"
     CDS             complement(2481..3080)
                     /locus_tag="KR231_003099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TerD family protein"
                     /protein_id="HBH0005455.1"
                     /translation="MAIELKKGQKINLTKKENSDLGEILVNLNWNQKVQKKGFFGSLR
                     SSNIDLDLGCLFEMKNGVKGAVQALGNAFGSLDNPPFAQLDGDDRTGSNTQGENLRIN
                     GNKIKDIKRILIYAFIYEGVANWSEADGIVTIKQKQDSDLVVKLDEHKNGYNMCSIAL
                     IENVNDETFSVEKVVKYFKGHREMDTEFHWGLKWVAGRK"
     gene            complement(3183..3980)
                     /locus_tag="KR231_003100"
     CDS             complement(3183..3980)
                     /locus_tag="KR231_003100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein"
                     /protein_id="HBH0005456.1"
                     /translation="MKFKKLLCLLLCLVLTLAVVGCSKAKDDKKIVVGATLVPGGELL
                     EELKPLIKEKGYTLEVKNFDDYILPNEALNNGEIDANLFQHEPYLKEAVKAKGYKIMA
                     GKKLYVCPAILYSYKIKSVDEFKKGDTIAISNNPSSCSKNLRYLESIGLLTLPKGDGL
                     VSPKDIIENPKGIQFKELDIAQIPSSLPDVTAAFIDTTYAVPAGLDAKKNGIYTAPIN
                     DEYANLLAFRTEDKDSEKIKVLQDVLTSDKARSLIEEKYKGIVIPTF"
     regulatory      complement(4093..4198)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00162"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="SAM riboswitch class I; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="S-adenosylmethionine"
                     /db_xref="RFAM:RF00162"
     gene            complement(4290..5276)
                     /locus_tag="KR231_003101"
     CDS             complement(4290..5276)
                     /locus_tag="KR231_003101"
                     /EC_number="6.3.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate--protein ligase"
                     /protein_id="HBH0005457.1"
                     /translation="MLLIYNEKTNPYFNLAMEEYLLKNFDEDLFILWRNEPSIIVGKN
                     QNTLSEINLEYIKEYSIPVVRRQSGGGAVFHDLGNINFTFIACNNNNFSDFRRFTQPI
                     IDLLKTLDVNAEFSGRNDLLIDGKKFSGNAQYNYKNKVMHHGTLLFSSEINDLSKALK
                     VKPIKFEGKGIKSVKSRVTNISEHLHSKMDILEFKDAIMDYLSKTNTDNTNYCLSEHD
                     IKQIEKLTKSKYETWDWNFGNSPKYTLSNELKYSGGNVEFNLNVDKGIITSIKFFGDF
                     FGKCDVAFVENKLIGIRHEENALRNTLDSIEINDYFLGADTDILVSGILGVK"
     gene            5760..7490
                     /locus_tag="KR231_003102"
     CDS             5760..7490
                     /locus_tag="KR231_003102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Na+/H+ antiporter NhaC family protein"
                     /protein_id="HBH0005458.1"
                     /translation="MRNKKINIIFLTTIMFIMSTVMVFAEEDIDTIALANAEKFGILT
                     LIPPLVAIILAFITKNVIISLLIGILSGSFIIKASGINVFATFIQAFLDLVDRALVSL
                     ADPWNAGIILQVLAIGGVINLVAKMGGAKAIAEALAKRAKSAKGTQLITWFLGLLVFF
                     DDYANSLIVGPMMRPVADKMKISREKLAFIIDATAAPVAGLAIISTWIGLEVGLIHDA
                     FESISIDVDAFGIFLNTIPFRFYNILILAFIVISALLLKEFGPMRKAEIKSRSRKISI
                     DLDEGVEELDDLAPKNGVKLSVWNAIIPIGTLIIVALASFYYSGYTSIMGGDDKALIQ
                     LFTNSPYSFEAIKEAFSASDASRALFQSALVASLVAIIMAVVKKIFTISEAIDVWIDG
                     MKSLVITGVILILAWSLSSVIKELGTAKFLIHLLSGSLPPFLLPSLIFGLGAIISFAT
                     GTAYGTMGILMPLAIPLAYSLNPDMSYVIVSTSAVLTGAIFGDHCSPISDTTILSSMG
                     AGCNHIDHVNTQMPYAIFTAVITIVFGYIPAGLGLPIYIVLPVAIAAIFVGIQIIGKK
                     VDEAEIELVE"
     gene            7600..7680
                     /locus_tag="KR231_003103"
     tRNA            7600..7680
                     /locus_tag="KR231_003103"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:7634..7636,aa:Leu,seq:tag)
     gene            8015..8530
                     /locus_tag="KR231_003104"
     CDS             8015..8530
                     /locus_tag="KR231_003104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861286.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HXXEE domain-containing protein"
                     /protein_id="HBH0005459.1"
                     /translation="MEKYIWLFPLLFIFHDMEEIIGFGIWLKKNKSMLDKKYPFISKV
                     YENYSTEGMAFAVFEEFILCIIFCILTVITENQYVYLLWLGSFIAYTLHLVIHIGQSI
                     IIRKYIPSLITSIICLPISIWCISKSIYIVDCEMSTTILYSIIGIIIVALNLKFAQSL
                     IGKFTKWMSNI"
     regulatory      9022..9126
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00504"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="glycine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="glycine"
                     /db_xref="RFAM:RF00504"
     gene            9336..11810
                     /gene="gcvPA"
                     /locus_tag="KR231_003105"
     CDS             9336..11810
                     /gene="gcvPA"
                     /locus_tag="KR231_003105"
                     /EC_number="1.4.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminomethyl-transferring glycine dehydrogenase
                     subunit GcvPA"
                     /protein_id="HBH0005460.1"
                     /translation="MNELKRVSLYNIHKELGAKLVEFAGWEMPLEYEGINKEHEKVRK
                     SAGIFDVSHMGEVQIKGAESEKFIQNLVTNDISALKINDIIYTPMCYENGGVVDDLLI
                     YKFGEEDYLLVINAGNIDKDVAWIIKQSEGYNVDIKNISSEVSQLAIQGPKAEEILQK
                     ITDIDLNSIKFYKSIPSTKVCGCPCLVSRTGYTGEDGFEIYCKNKYVEIIWNEVLKVG
                     GEDICPAGLGCRDTLRFEAALPLYGHEINEHISPIEGGLSIFVKTNKESFIGKSILSK
                     EKESGAKRKLVGFEMQGKGMPRNGYDIRIGDKTVGFVTTGCASPTTGKILGMGIIDSE
                     YAKVGNEIGIAIRKKVVPAVIVKKPFYKKQYKKDNIILNKENKFSYIPATSEDKSKML
                     KVVGLNSVDELFSDIPEEVKLKRDLNLEIGKSELEVSKIVKRLSEENLSLEDLTCFLG
                     AGAYDHYIPSIIKHITSRSEFYTAYTPYQAEISQGTLQVVFEFQSMIAEITGMEIANA
                     SMYDGATAAIEACIMAMNQTRKSKIVVSKTIHPETLSILRTYLQYKDCEIVEIDFCNE
                     YGTTDIEKLKASVDKDTACVLIQTPNFFGIIEEMEEIEKITHENKAMLIMSVDPISLG
                     VLKTPGEIGADIVVGEAQSLGNPLNFGGPYVGFLASKSKYTRKMPGRIVGQSLDVEGK
                     IAYVLTLQTREQHVRREKATSNICSNQALNALVASIYIATMGKEGFKEVGMQSMKKAH
                     YTYNKLVQTGKYKPIFKGKFFKEFAVQGNLNIETINDKLLEENILGGYNLEYNYPELK
                     NSTLLCVTEKRSKEEIDKLVGIMEGL"
     gene            11810..13267
                     /gene="gcvPB"
                     /locus_tag="KR231_003106"
     CDS             11810..13267
                     /gene="gcvPB"
                     /locus_tag="KR231_003106"
                     /EC_number="1.4.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminomethyl-transferring glycine dehydrogenase
                     subunit GcvPB"
                     /protein_id="HBH0005461.1"
                     /translation="MKEYNSLLIDISKKGRKAYSLPKLDIDDIKIENMIDQDMARQSE
                     LNLPEVGELELVRHYTLLSNKNFGVDTGFYPLGSCTMKYNPKINEDMAALPNFTGMHP
                     YQSSDTAQGSLSLMYDLSRRLAEITGMDEVTLQPSAGSHGEFTGLMIIKAYHENRGDH
                     KRTKVIIPDSAHGTNPASAAMANFDVIQIASDKNGAVDINALKEVLNDEVAALMLTNP
                     STLGLFEKNIKEIATLVHEAGGLLYYDGANMNAIMGITRPGDMGFDVVHLNLHKTFST
                     PHGGGGPGAGPVGVKKELVPFLPIPVIERKEDKYVLNYDREKSIGKIKNFYGNFGVLV
                     RAYTYILTMGRDGLKEASEMAVLNANYIKESIKDDYILPIDTLCKHEFVLGGLPRGEA
                     NIKTIDIAKRLLDYGYHPPTMYFPLIINEALMIEPTESESIETLDSFIEAMKSVAKEA
                     KEEPELLKTAPHNTLVKRVDDARAVKKPILTWSQR"
     gene            13690..16047
                     /locus_tag="KR231_003107"
     CDS             13690..16047
                     /locus_tag="KR231_003107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893215.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IC family P-type ATPase"
                     /protein_id="HBH0005462.1"
                     /translation="MDKVNLERYSCDINVGLNKNQLQSRIDDNLINAFDNGKTKTYKQ
                     IFKDNIFTLFNLINIVLVCLLVSVGSFKNTLFIFIAVINTIIGVIQEIRAKRLLDNLS
                     VIVSNKVSVIREKEKKEIDVQELVLDDIMILKTGNQICADSKVLNGKLEVNESLVTGE
                     SDIIIKNKGDFLYSGSFVVSGEAFVRVENIGKDNYANKIANDAKISKKHNSQLRNSLN
                     AILKIVGIIIIPLGIILFAKQHFGNGDSIATSVVGTVAAVNGMIPEGLTLLTSIALAV
                     GTIKLASHKTLVQELYCVETLARVDTLCLDKTGTITEGKMQVDDIVMLEEVDINEIMG
                     NICNSLKDDNATLNAIRDKYNVLDTYKAKNLIPFSSERKYSGVTFENKGTYLLGAFEF
                     IFKEKNKKLRIEVERYSKKGNRVIVLAHSDSYMEDNNIPEDIKPLAFILILDKIRDEA
                     KETLEFFYNEGVDIKIISGDNPITVSEVARKAGLKTASNFIDATTLKNDSDIYKAVDK
                     YSVFGRVSPQQKKQMILALKKQNHTVAMTGDGVNDVLALKEADCSIAMASGSDVTKNV
                     SNLVLLDSNFASMPKVVMEGRKVINNIQRASSLFLVKTIFSFFLSLLTLFFFSRQYPF
                     VPIQLSLIGAVTVGIPSFFLALEANKSRISGNFLLNILKNALPGALCVTVNVIIVYNI
                     VEYLGYSSSVFSTMCAILTGVCGLLILRQQCLPFNKERLFLIVSMTIAFVIGILFLGG
                     LFSFVALSRELILITMALAILMPIMIKVMLFVLDEILETIVPDLN"
     gene            complement(16133..16450)
                     /locus_tag="KR231_003108"
     CDS             complement(16133..16450)
                     /locus_tag="KR231_003108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrimidine/purine nucleoside phosphorylase"
                     /protein_id="HBH0005463.1"
                     /translation="MSEFKNVTAVKKANVYFDGKVSSRVIILPNGERKTLGLMLPGEY
                     TFSTREEEIMEMLAGSMDVKLPGSNEFVTYKEGQKFNVPSDSSFDLKVNEVVDYCCSY
                     IAD"
BASE COUNT         6348 a         1929 c         2726 g         5746 t
ORIGIN      
        1 aataaaatat gaagttatac tagacaaaaa gaataactct taaatataat taagttatat
       61 aataatatat aattataatg atataatttt aataggtggt ttgtaattaa aaagtttata
      121 aattatatta atagtaataa tctataagaa cttatatatt agaaaaaatt ttgtatatat
      181 agaggactct aaagatgaac tatgtaaaac aaggtttata tattctaatt gtatagaaaa
      241 tttattgtaa acgcatgtat attattagaa aaaatagttt gaaggtattc aataaacata
      301 aaaaacaata taggggataa aggtgtttta tgaagagatt tttgaggaga attatcttag
      361 ttttatttat tttgttgatt tttataagtt ttatttctat taaattaatt cataatgttg
      421 gagattatgg aaaattgatt aattatgttg ggattgttcg tggagctagc caacgtctaa
      481 ctaaactaga gatgaatcat caaccaaatg atgaattaat agaatatatt gatgaaatcc
      541 tacaggagtt gattacaggg catggagatt atggtttagt aatcactgat tgtaatgaat
      601 acaatgagga cttactttta ttagaaaaaa agtgggaaga tttaaatatt gaaattaaaa
      661 aagtaagaat gaaagaacag aataaccagt tattaagtat aagtgaagag tttttttctc
      721 ttgcaaatga tacagtgttt aaaatagaaa acttttctaa agaaaaaagt aattacttaa
      781 tgactttaat aataattata tctattatag gtatattagc atgtatcata ttgattttac
      841 aatatagtaa aaaaatggtt agactggaaa aattaaatgt agatttaaaa aatattgcat
      901 ataaagatga actaacagga gtaaatacta tagaaaaatt taaattggat gcaaatcaaa
      961 atatttgtat acataaggat aagaaatttg ctgtattcta tattgatttt gaaaacttta
     1021 aatacattaa tgatatattt ggatatgatt atggtgacat gatactgaaa agatatgcta
     1081 atcttatgat gaatgacata gggaaatatg aaatatttgc aagagaaatt gcagatagat
     1141 ttgttgcgtt aagatgctat gtagataagg aagatttagt ggtaagacaa cgagatgtag
     1201 acaatgaact aattaatata acaaatgaaa ttaaaaataa acatagtatt actgttgtta
     1261 gtggaatttg ttgtattgaa gatgtaaatg aaaaattaag tatagatggt ttaataaata
     1321 gagcaaattt tgcacaaaaa actgttaaga ataaaccagg tactaattat gctttttata
     1381 atgacagtat tcgtaaaaaa atgattgaag aaaatactat caagagtaga atacatgaag
     1441 ctattgaaaa aagagaattt atagtttatt tacagcctaa agttaattta catagtcaaa
     1501 aaataaattg tgcagaagct ttagttcgtt ggcttactcc ggataaaggt attatatcgc
     1561 cagcaatatt tattccagta cttgagaaga atttttttat tgccttagta gataagtatg
     1621 tttttgagga ggtttgtaaa tggattagaa agaggttaga tgaaaataaa ccttttgttc
     1681 agatatcagt taatgtttca agaatacaat tttataacac taaatttgta gaaacttatt
     1741 ccaatataca aaataaatac aggataccta aaaatactat agaaattgaa tttacagaga
     1801 gtgttgcttt tgagaatcaa aaacatcttt tggaaattat acatgatttg catgaaaatg
     1861 gatttacttg ttctttagat gattttggaa aaggttattc gtctttaagt gttttaaaag
     1921 atttaccatt tgatgtttta aagcttgatt ctatgttttt caaggctagt ttagataaag
     1981 ataaagagaa aatagtaata aaaaatattg tacatatgtt aaaagaactt aatatcacaa
     2041 ctgttgctga gggcattgaa tgcaaggaac aagttgaatt tcttagggat attgggtgtg
     2101 atttagttca gggatttgta ttttataaac caatgccaat attagaattt gaaaaaatat
     2161 tggataaaga gtttgtttat aatagctaaa atgtacttta taaaatatga actaattaag
     2221 taaaattatt ttgtactgaa taaattttta ctttatttac agaataatga ttatttacag
     2281 aaaagcgcga aaagtgtatt cctttaagtg tgggatggat agcacaaata gaggagaaaa
     2341 aatattggcc atataagaat gcataataat ataaatattt gaaaggtcag cattatataa
     2401 aaattaaaaa gaaaataaat aatttttcta taaaaaagag actatgagaa aatttactca
     2461 tagtctccta aataatgtat ttattttctt cctgcaaccc attttaatcc ccaatgaaat
     2521 tcagtatcca tttctctatg acctttgaag tatttaacta ctttttcaac actgaatgtc
     2581 tcatcattta cattttctat caatgctatt gaacacatat tatagccatt tttatgttca
     2641 tcaagtttga caactaagtc tgaatcttgt ttttgtttga ttgttacaat tccatcagct
     2701 tcagaccagt tagctacacc ttcgtatata aaagcataaa taagtattct ttttatatct
     2761 tttattttat taccatttat tcttaaattt tctccttgtg tattacttcc tgttctgtca
     2821 tctccatcta attgagcaaa aggtggattg tctaaactac caaaggcatt tcctaatgct
     2881 tgaacagctc cttttacacc atttttcatc tcaaataggc aacccaaatc taaatctata
     2941 ttactgcttc ttaaagagcc aaaaaaaccc tttttttgta ctttttgatt ccaatttaaa
     3001 ttaactaaga tttcacctaa atcgctattt tccttttttg taaggtttat tttttgtccc
     3061 ttttttaatt ctatagccat agtaatcttc ctccacaaac atagatttat ttaaatggta
     3121 gcacttaata agtcaatatt caacaagatt agaataataa tattaaaatt atactaaata
     3181 tactaaaaag taggaatcac aatacctttg tatttttctt caattaagct tcttgcttta
     3241 tctgatgtaa gaacatcttg tagaacttta atcttttcac tgtctttatc ttcagttcta
     3301 aatgctaaaa gatttgcata ctcgtcattt ataggagctg tataaattcc gtttttcttg
     3361 gcatcaagac cagcaggtac agcataagta gtatctataa atgcagcagt cacatctgga
     3421 agagaagatg gaatttgagc aatatctaac tctttgaatt gtattccctt tggattttct
     3481 attatgtcct taggactaac taatccatcc cctttaggta acgttaaaag tccaatactt
     3541 tcaaggtatc taaggttctt agaacaagaa gatgggttat tgcttattgc aattgtatct
     3601 ccttttttaa attcatcaac agattttatc ttataagagt aaagtattgc tgggcataca
     3661 tatagttttt taccagccat tattttgtaa cctttggcct taacagcttc ttttagataa
     3721 ggttcatgtt gaaatagatt tgcatcaatt tcaccattat ttaaagcttc gtttggaagt
     3781 atgtaatcat caaagttttt aacttctaaa gtatatcctt tttctttaat aagtggtttt
     3841 aattcttcta ataactctcc tcctggaact aaagtagcac caacaacaat ttttttatca
     3901 tctttagctt tagaacatcc aaccacagct aaagttaata ctagacataa taacaaacat
     3961 aataattttt tgaatttcat ataaattccc tcctgaatat aattgattag ttaaaaataa
     4021 aataccattc tttatcacac tgcaaaataa aaataagcct gagtttaaac tcaggcttta
     4081 aaagctaatt tagactcatc tttcagtata atactgcagg atttagcacc aatgtatata
     4141 aaaatatact ggttgctggg tttcataggg ccagtccctt caccactctg gataagaagt
     4201 atcaattttt aattatgtta taaatattat catgattttt tacgtctgta aacataattt
     4261 tataaatatt ttaaaatctt taatgtattt tatttaacac ctaaaattcc agaaactaga
     4321 atatcagtat cagcacctaa gaaatagtca tttatttcaa tagaatccag agtatttctc
     4381 aaagcatttt cttcatgcct tataccaata agtttatttt ctacaaatgc aacatcacat
     4441 tttccaaaaa aatctccaaa aaattttata ctagttatta tgcctttatc aacatttaaa
     4501 ttaaactcaa catttccacc agaatatttt aattcatttg aaagagtata ttttggtgaa
     4561 ttaccaaaat tccaatccca agtttcgtat tttgatttag taagcttttc tatttgtttt
     4621 atatcatgct cactcaaaca ataattagta ttatcagtat ttgttttaga aagataatcc
     4681 attatagcat ctttaaattc taatatgtcc atttttgaat gtaaatgttc acttatattg
     4741 gttacacgag attttacaga ttttattcct tttccttcaa attttatagg tttaaccttt
     4801 aatgcttttg agaggtcatt tatttcagat gaaaataaaa gagtaccatg atgcattact
     4861 ttgtttttgt agttgtattg agcatttcca gaaaatttct tgccatctat aagaaggtca
     4921 tttcttccag aaaattcggc attgacatct agtgttttaa gtaaatctat tatgggctga
     4981 gtgaatcttc tgaaatcact aaaattatta ttgttacaag ctataaatgt aaaatttata
     5041 tttcccaaat catgaaatac agctccacca ccagactgtc tcctaacgac aggtatagaa
     5101 tattctttta tatattctaa atttatttca gaaagtgtgt tttggttttt tccaacaatt
     5161 atagaaggtt cattcctcca taaaataaat aagtcttcat caaaattttt tagaagatat
     5221 tcttccattg ctaaattaaa ataagggttt gttttttcat tataaattaa taacattaaa
     5281 gtagttcctc catagaattg ataaaatttt tattatgaat acaattaatt ttataattcg
     5341 acaataatat aaaaactcct ttaaattaga aattttaaaa actaccttgc aaagtttaaa
     5401 taaataatat atactcaaaa tatgtttaat aaaagtgaat agaagggtag aggcgcaata
     5461 atctatcagt actaataagg agttaagcac agagatttat taggaaagga gatattgccg
     5521 aagttttata atcgatgctt taagattata ttgctggggg tacatagaaa atatgtacaa
     5581 ctgtcacagg tttatttgtg gtgagctatc atttaaggaa ttatattata tttattttta
     5641 ctattgttga tatattgtaa tgtttaagcc ttgagtgttt accactcaag gcttttttag
     5701 ttttattgta acataatacc ctgtacagtt cacaaaatta aaaggagagg gagatttata
     5761 tgaggaacaa aaaaattaat attatttttc tgacgacaat catgttcata atgtcaacag
     5821 taatggtttt tgcagaagaa gatatagaca ctattgcact agccaatgca gaaaaatttg
     5881 ggattttaac tttaatacca ccattagttg ctataatact tgcatttata actaaaaacg
     5941 taataatttc tttacttata ggtattcttt ctggtagttt tataattaaa gctagtggta
     6001 ttaatgtttt tgcgacattt atacaggcat ttttagattt agtagacaga gctttagtat
     6061 ctttagcaga cccttggaat gcagggataa tactacaggt tttggcaatt ggaggagtaa
     6121 taaatcttgt tgctaaaatg ggaggagcta aagctatagc tgaagcactt gctaaaagag
     6181 caaagtcagc aaaagggaca cagcttataa catggttttt ggggctttta gtattctttg
     6241 atgattatgc caattcacta atagtaggtc ctatgatgag acctgttgca gataaaatga
     6301 aaatatcgag agaaaagcta gcatttataa tagatgccac agcagcacca gttgctggtt
     6361 tagctataat atctacatgg ataggtcttg aggttggttt aatacatgat gcttttgaaa
     6421 gtataagtat agatgtagat gcatttggta tatttttaaa tacaatacca tttagatttt
     6481 acaatatatt aatattagct ttcattgtaa tatcagcatt attattaaaa gaatttggtc
     6541 caatgagaaa agctgagata aaatctagaa gtagaaaaat tagtatagac cttgatgaag
     6601 gcgtagaaga gttggatgat ttagctccaa aaaatggagt aaaattgagt gtatggaatg
     6661 ctataatccc aataggaaca ttgataatag ttgcattagc atcattttat tatagtggat
     6721 atacatctat aatgggagga gacgataagg ctctgataca actatttaca aattctccat
     6781 attcttttga agcaataaaa gaagcattta gtgcatctga tgcatctaga gcattattcc
     6841 agtctgcact tgttgcaagt ttagttgcta ttataatggc tgtagtaaaa aagattttta
     6901 caatatcaga agcaattgat gtttggatag atggaatgaa aagtttagta atcactggtg
     6961 taatattaat acttgcatgg tcattaagtt cagtaataaa agagttaggt acagctaaat
     7021 ttttaataca cctattatca ggttcactac caccattctt attaccaagt ttaatatttg
     7081 gtttaggagc aataatatct tttgctactg gaacagctta tggaacaatg ggtatactta
     7141 tgccacttgc aattccatta gcatactcat taaatcctga tatgtcttat gtaatagtaa
     7201 gtactagtgc agttttaaca ggtgcaatat ttggagacca ttgttctcca atttcagata
     7261 caacaatact ttcttcaatg ggagctggct gtaatcatat agaccatgtt aacactcaaa
     7321 tgccatatgc tatatttaca gcagtaatca ctattgtatt tgggtatata ccagctggac
     7381 ttggattgcc aatatatata gtattaccag tggcaatagc tgctatattt gtaggtattc
     7441 aaataattgg taagaaagtt gatgaagcgg aaatagaact tgtagaataa agatataaat
     7501 aagtttcacc ttttattatc actattttgt tagtttttag ataattttaa aaagttattg
     7561 aaaataatgg cgaaatatag taaaataaaa gagtgataag cggatgtggc ggaattggca
     7621 gacgcactag acttaggatc tagcgccatt ggcgtggggg ttcgactccc ttcatccgca
     7681 ctttacagta cttaattgta ctgaaaaaaa ctggggttgc tggctttcgg agtgggctat
     7741 cccgttttta tttttttgta tatataatag attggcactt tagtataagg tgcttttttt
     7801 ataggcaaaa acagtacatt tatttctgtt ttattatcat tcatctatta gaatatactt
     7861 tagttaagaa tgtgttaata agcagtgttc acattcttga taaaatgtgg aataatatgt
     7921 atttttacta agacggaaat gaaataatta aaccattaaa taatattata agatgatgaa
     7981 taagtagata aatcaaattt tgtaggagga tattatggaa aaatatatat ggttgtttcc
     8041 attacttttt atttttcatg atatggaaga gataataggt tttggaatat ggcttaaaaa
     8101 aaataaatca atgcttgata agaagtatcc atttatcagt aaagtttatg aaaattatag
     8161 tactgaaggc atggcatttg ctgtgtttga agaatttatt ttatgcatta ttttctgtat
     8221 acttacagtt ataacagaga atcagtatgt atatctacta tggttaggta gttttatagc
     8281 atatacctta catttggtaa ttcatatagg gcagtcaatc ataataagaa aatatatacc
     8341 ttcacttatt accagtatca tatgcttacc aataagcatt tggtgtataa gtaagagtat
     8401 ttatatagtt gattgtgaaa tgagtacaac aattctgtac agtataattg gcattataat
     8461 tgtagcattg aatttaaagt ttgcacagtc gctgattgga aaatttacaa agtggatgtc
     8521 aaacatataa attttagttt attggacagt tcaaggaatc agaaattgga attttatagt
     8581 attaatattt tatggtatta atataatgta taaaatttta tagcaatgta tttcataagt
     8641 ataaagtgac tagaatttta agaaatatac aaattctata aaaactaaat aatttcaagt
     8701 atattttaaa aatcttattt ttcacaagtt taaaattgta aacgatttca tcaagtctat
     8761 gaatatactt ttaacatgtt atagtaaatc tcaatataaa tttacatttg gttctttgtg
     8821 tgttatttta ataataaatt aagtgaaaat gttattttac attaatatat aatatctttg
     8881 cataagagtg aataatataa aagagaaata attgataata aaaacttaac aaaaaaatta
     8941 atacataaaa aaaaataaat ataatgtgtt gacatttaat tgaaatattc atacaataaa
     9001 attgaaaata aatatttcca aatgagatta gcgagagagt cctttatacg aaaaggcgcc
     9061 gaagaagaaa tttaagaaat gccaattttt agagaagctt tcaggcaaaa atatcgctaa
     9121 ttgatgggac tctggagaga cttaagttaa gatactataa gtcaccgaag aagcaaaata
     9181 atattaaatt attaaatctt tcaggtatac aaacagggat atataggcta ggattatttt
     9241 ccatgctgat atatcttttt tttatgaaaa agtacaggaa ataatatcaa agttacttaa
     9301 atacagtagg tctaattttc tagggagggt tatatatgaa tgaattgaaa agagtatctt
     9361 tgtacaatat acacaaagag cttggagcaa aacttgttga atttgctggt tgggaaatgc
     9421 ctttagaata tgagggtata aataaagagc atgagaaggt cagaaaaagt gcaggtatat
     9481 ttgatgtatc tcatatggga gaggtacaga taaagggagc agagtcagaa aaatttatac
     9541 aaaacctagt tacaaatgat ataagcgcat taaagataaa tgatattata tatacaccta
     9601 tgtgttatga aaatggtgga gtagttgatg atttattaat atataaattt ggtgaagaag
     9661 attatttatt agtaataaat gcaggtaata tagataaaga tgtagcatgg ataataaaac
     9721 aaagtgaagg atacaatgta gatataaaaa atatatctag tgaagtgagt caattagcaa
     9781 ttcaaggacc taaagcagaa gaaattcttc aaaaaatcac agatatagac ttaaactcaa
     9841 taaaatttta taagtcaatt ccatcaacaa aagtatgtgg ttgtccttgt ttagtttcaa
     9901 gaacaggata tactggggaa gatgggtttg agatatactg taaaaataaa tatgtagaaa
     9961 taatttggaa tgaagttcta aaggttggag gagaagatat atgtccagct ggtctaggtt
    10021 gtagggatac tttgagattt gaagcagctc tacctctata tggacatgaa ataaatgaac
    10081 acatatctcc aattgaaggt ggtttatcta tctttgtgaa aacaaataaa gaatcattta
    10141 ttggcaaatc aattttatca aaagaaaaag aaagtggagc taaaagaaag ttagtaggat
    10201 ttgaaatgca aggtaaagga atgcctagaa atggatatga tataaggatt ggtgataaaa
    10261 cagttggatt tgtaacaaca ggatgtgcat ctccaacgac aggaaaaatt ttaggtatgg
    10321 gaattataga ttctgaatat gcaaaagtag gaaatgaaat aggtatagca atcagaaaaa
    10381 aagttgttcc tgctgtgata gttaagaaac ctttttataa aaaacaatat aaaaaagata
    10441 atattatatt aaacaaagaa aataaatttt catatatacc tgctacaagt gaagataaat
    10501 caaaaatgtt aaaagtagtt ggattaaatt cggttgatga attattttca gatataccag
    10561 aagaagtaaa attaaaaaga gatttaaatt tggaaattgg aaaatctgaa ttagaggtaa
    10621 gcaaaatagt aaaaagattg tcagaagaaa atttaagttt agaagacttg acttgttttc
    10681 ttggtgctgg tgcatatgac cattatatac catcaattat aaaacatata acttcaagat
    10741 ctgaatttta tacagcatat actccatatc aagctgaaat aagtcaggga actttacaag
    10801 tagtttttga atttcaatct atgattgcag aaattacagg tatggaaatt gcaaatgcat
    10861 caatgtatga tggagcaact gctgcaatag aagcatgtat aatggcaatg aatcagacta
    10921 gaaaaagtaa aatagtagtg tcaaaaacta ttcatcctga aactttgtca atattaagaa
    10981 cttacttaca atataaagat tgtgagatag tagaaattga cttttgtaat gaatatggca
    11041 ctacagatat agaaaaatta aaagcttctg tagacaaaga tacagcatgt gttcttatac
    11101 aaactcctaa tttctttgga attattgaag aaatggaaga aatagaaaag ataactcatg
    11161 aaaataaggc tatgttaatt atgagtgtag acccaatatc attaggagtt ttaaaaacac
    11221 caggtgagat aggtgcagat attgttgttg gagaagctca atcacttgga aaccctctta
    11281 attttggagg tccttatgta ggatttttag ctagcaaatc taaatatact agaaaaatgc
    11341 caggaagaat agttgggcaa agtttagatg tagaaggtaa aattgcatat gtattaactt
    11401 tacaaactag agaacagcat gtaagaagag aaaaagcaac ttctaatata tgttcaaatc
    11461 aagctttaaa tgctcttgta gcttcaatat atatagctac tatgggtaaa gaaggattta
    11521 aagaggttgg tatgcagtct atgaaaaaag cacattatac ttacaataag cttgtacaaa
    11581 ctggaaaata taagccaata tttaaaggta agtttttcaa agaatttgct gtacaaggaa
    11641 atcttaatat agaaactata aatgataaac tcttagaaga aaatatatta ggtggttata
    11701 atttagaata caattatcca gaattaaaaa attcaacttt gctttgtgtg actgagaaaa
    11761 gaagcaaaga ggaaatagat aagttagttg gaataatgga gggattataa tgaaagaata
    11821 caatagtttg ttgatagata tatctaaaaa aggtaggaaa gcatactcac ttccaaagtt
    11881 agatatagat gatataaaaa tagaaaatat gattgaccaa gatatggcaa gacaaagtga
    11941 gttgaatttg ccagaagttg gtgaattaga attagttaga cattatacat tattatcaaa
    12001 taaaaacttt ggagttgata caggttttta tcctttgggt tcttgtacta tgaaatataa
    12061 tcctaaaata aatgaagata tggcagcact tccaaacttt actggaatgc atccatacca
    12121 atcttcggat acagctcaag gttctctttc tttgatgtat gatttatcaa gaagacttgc
    12181 agaaattaca ggtatggatg aagttacact acaaccttca gcaggttctc atggtgagtt
    12241 tacagggctt atgattataa aagcatatca tgaaaataga ggtgaccata agagaaccaa
    12301 agtgataatt ccagattctg cacatggaac aaatccagca agtgcagcta tggcaaactt
    12361 tgatgtgatt caaatagcat ctgataaaaa tggagctgta gacataaatg cattaaaaga
    12421 ggttttgaat gatgaagtag cagctcttat gcttactaat ccaagtactc ttggtttatt
    12481 tgaaaaaaat ataaaagaaa tagctactct tgtacatgaa gcaggaggac ttttgtacta
    12541 tgatggtgca aacatgaacg ctattatggg gataacaaga cctggagata tggggtttga
    12601 tgtggttcat cttaatcttc ataagacttt ttcaactcct catggaggtg gaggtccagg
    12661 agctggtcct gttggagtta aaaaagaatt agtacctttt ttaccaatac cagtaattga
    12721 aagaaaagaa gataagtatg tactaaatta tgatagagaa aaatctattg ggaaaattaa
    12781 aaatttctat ggtaattttg gagttcttgt aagagcttac acatatatac taactatggg
    12841 aagggatgga cttaaagagg ctagtgaaat ggcagtttta aatgctaatt atataaagga
    12901 aagtataaaa gatgattata ttttgccaat agataccttg tgtaagcatg agtttgtatt
    12961 aggtggattg ccaagaggag aggccaatat aaaaactatc gatattgcaa aaagactact
    13021 agattatgga taccatcctc caacaatgta ctttcctctt attataaatg aggcacttat
    13081 gatagaacct acagaaagtg agagtataga gacattagat agttttatag aagctatgaa
    13141 aagtgttgct aaagaggcaa aggaagaacc agaactattg aaaactgctc cacataatac
    13201 tttggtcaaa agagtagatg atgcaagggc agtaaagaaa cctatactaa catggtcaca
    13261 aagataaata gttaaaaagt agagatttaa agtataaaga gaattaaatt tgtaagaaaa
    13321 agctatctaa cttaatctag tttagatagc ttttttgtat attagtatgt atggtatttt
    13381 ctatataaag ttttaaatta tattagtgct tatatagaat attgatatga tgattatgta
    13441 tagatattaa taagaattgt tgaatttatc ttgccttaac tttatttact cttttatatt
    13501 aagaaaaact taactaaaat atagcgaaat tcataaaaat ttaggaaatc ttaagaatta
    13561 taatatttaa atctttagat ttatatttta ttatataaac tatagaataa taaaataaaa
    13621 aaattgagaa ttttataata tatttgtaga tttgagtata aaaaagtgct aagttgaaag
    13681 gagtaaaata tggataaggt taatttagaa aggtatagtt gtgatataaa tgttggttta
    13741 aataaaaatc aacttcaaag tagaatagat gataatttaa ttaatgcatt tgataatgga
    13801 aaaaccaaaa catataaaca aatttttaaa gacaatatat ttacactttt taatctcata
    13861 aatattgttt tagtctgttt attagtttca gttggttctt ttaaaaatac cttatttata
    13921 tttattgctg taattaatac tattatagga gtaatacaag agataagagc taaaagatta
    13981 ttggacaatc tatctgttat agtttcaaat aaggtatctg tcataagaga aaaagagaaa
    14041 aaagagattg atgtacaaga attagtatta gatgatatta tgattttaaa aacaggtaat
    14101 caaatttgtg cagattcaaa agttttaaat ggaaaattag aggtaaatga gtctttggtt
    14161 acaggtgaat ctgatattat tataaaaaat aaaggcgatt ttttatattc tggaagtttt
    14221 gtagtttctg gagaagcttt tgtaagagtt gaaaatatag gaaaagataa ctatgcaaat
    14281 aagatagcta atgatgcaaa gatttctaaa aaacataatt ctcaacttag aaattcatta
    14341 aatgcaatat taaaaattgt aggtataata ataattcctt taggaattat attgtttgca
    14401 aaacaacatt ttggaaatgg agattctata gctacatctg tagtaggtac agtggcagct
    14461 gtaaatggta tgataccaga gggattaaca ttacttacga gcattgctct agctgtagga
    14521 actataaaac ttgctagtca taaaacttta gtgcaagaac tgtactgtgt agagactctt
    14581 gctagagttg atacactatg tcttgataag acaggtacaa ttacagaagg taaaatgcaa
    14641 gttgatgata tagtaatgtt ggaagaagtg gatattaatg aaataatggg gaatatatgt
    14701 aattctctca aagatgataa tgcaacacta aatgcaataa gagataagta taatgtttta
    14761 gatacgtata aagctaagaa tttaatacca ttttcttcag aaagaaaata cagtggggtt
    14821 acctttgaaa ataaaggtac atatttatta ggtgcatttg agtttatatt taaggaaaaa
    14881 aataaaaaac ttaggataga agttgaaaga tattctaaaa aaggaaacag agtaatagtt
    14941 ttagctcata gtgattctta tatggaagat aataatattc ctgaagatat aaagccacta
    15001 gcttttatat tgatattgga taaaattaga gatgaagcta aggaaacttt agaatttttt
    15061 tacaatgaag gtgtagatat aaaaattata tctggtgaca atcctataac agtaagtgag
    15121 gtagctagaa aagcaggtct taaaacagct agtaatttta ttgatgcaac aacacttaaa
    15181 aatgatagtg atatatacaa agcagttgat aaatacagtg tttttggaag ggtaagccca
    15241 caacagaaaa aacaaatgat tttagcatta aaaaaacaaa atcatacagt agctatgact
    15301 ggagatggtg taaatgatgt actagcactt aaagaagcgg attgtagcat tgccatggca
    15361 tctggaagtg atgttactaa gaatgtgtct aatttagtct tattagattc aaactttgca
    15421 tcaatgccaa aggttgttat ggagggaaga aaagtaatta ataacattca aagagcatct
    15481 tctttgtttt tagtaaagac aattttttca ttcttcttgt cgttattaac attattcttc
    15541 ttcagtagac agtatccatt tgttcctata caattatcac tcattggggc tgtaacagtg
    15601 ggtataccat cattcttctt agctcttgaa gcaaacaaaa gtagaatttc aggaaatttt
    15661 ttactcaata tattaaaaaa tgctttacca ggagcactat gtgtgacagt aaatgtaatt
    15721 attgtttaca atatagttga atatttaggt tatagttcaa gtgtattttc cacaatgtgt
    15781 gctatattaa ctggtgtatg tggtctttta atattgagac aacaatgttt gccatttaat
    15841 aaagaaagat tatttttaat agtaagtatg actattgcat ttgttattgg gattctattt
    15901 ttaggtggat tattctcatt tgtagcattg agtagagaat taattctcat aactatggca
    15961 ttagcaatat taatgccaat tatgataaaa gttatgttat ttgtcttaga tgagatatta
    16021 gagacaattg ttccagattt aaattaattt taaaatgata taaataagag cagttttagt
    16081 tgaactgctc tttttagatg tgtttaattt tatgtaagaa tatgtatttt tattaatcag
    16141 ctatatatga gcaacagtag tcaacaactt cattaacctt taagtcaaaa cttgaatcac
    16201 taggaacatt aaatttttgc ccttctttat aagttacaaa ctcattgctt ccaggcagtt
    16261 ttacatccat acttccagca agcatctcca ttatttcttc ttctctagta gaaaaagtgt
    16321 attctcctgg caacattaat cctaaagttt ttctttctcc attaggcagt attattactc
    16381 tgctacttac cttaccatca aaataaacgt ttgccttctt tactgcagta acattcttaa
    16441 attcactcat tagataaaac ctccaaaatt atttgtacat atatattata taaaaataat
    16501 gtaaaaaatg ctatatattt acaaaaaaat ttagtattta ttaaaaaaat taataagaat
    16561 aaaaaagagg tgaaattgct taaattgata aaaaatataa aataaattgc aaagtaagca
    16621 agaaaagaat aagttgaaga gttatatatt ataaatatta aaaattttag tattaataaa
    16681 aaagatatta cattaatatg aaaatatagg agattagaag tgtttgatta aaaaatagct
    16741 acacacact
//
LOCUS       DAEPHU010000084        16350 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 01A10CD0081
            SAMN05941466-rid12468953.denovo.084, whole genome shotgun sequence.
ACCESSION   DAEPHU010000084 DAEPHU010000000
VERSION     DAEPHU010000084.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941466
            Sequence Read Archive: SRR6291087
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 16350)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16350)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068158.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 22:43:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,892
            CDSs (total)                      :: 3,805
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 87
            rRNAs                             :: 8, 1, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 55
            CDSs (without protein)            :: 55
            Pseudo Genes (ambiguous residues) :: 0 of 55
            Pseudo Genes (frameshifted)       :: 21 of 55
            Pseudo Genes (incomplete)         :: 28 of 55
            Pseudo Genes (internal stop)      :: 16 of 55
            Pseudo Genes (multiple problems)  :: 8 of 55
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16350
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941466-rid12468953.denovo.084"
                     /strain="01A10CD0081"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            <1..369
                     /gene="tuf"
                     /locus_tag="KR231_003109"
     CDS             <1..369
                     /gene="tuf"
                     /locus_tag="KR231_003109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009887863.1"
                     /note="EF-Tu; promotes GTP-dependent binding of
                     aminoacyl-tRNA to the A-site of ribosomes during protein
                     biosynthesis; when the tRNA anticodon matches the mRNA
                     codon, GTP hydrolysis results; the inactive EF-Tu-GDP
                     leaves the ribosome and release of GDP is promoted by
                     elongation factor Ts; many prokaryotes have two copies of
                     the gene encoding EF-Tu; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HBH0005464.1"
                     /translation="DNIGALLRGVQRNEIERGQVLAKTGSVKAHTKFTAEVYVLKKEE
                     GGRHTPFFDGYRPQFYFRTTDVTGACKLPEGIEMVMPGDNVTMEVDLINSIVVEEGLR
                     FSIREGGRTVASGVVATIIE"
     gene            619..768
                     /gene="rpmG"
                     /locus_tag="KR231_003110"
     CDS             619..768
                     /gene="rpmG"
                     /locus_tag="KR231_003110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004402360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HBH0005465.1"
                     /translation="MRVKVTLACTECKQRNYNTTKNKKNNPDRIELQKYCRFCKKHTT
                     HKETK"
     gene            794..1015
                     /gene="secE"
                     /locus_tag="KR231_003111"
     CDS             794..1015
                     /gene="secE"
                     /locus_tag="KR231_003111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecE"
                     /protein_id="HBH0005466.1"
                     /translation="MAAQKNDGAKTKKRFSLFGYLKETKQELKRVTWPTKKELFKNTS
                     IVLTVVISCTILVWGIDTILSGALALLLK"
     gene            1035..1577
                     /gene="nusG"
                     /locus_tag="KR231_003112"
     CDS             1035..1577
                     /gene="nusG"
                     /locus_tag="KR231_003112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination factor
                     NusG"
                     /protein_id="HBH0005467.1"
                     /translation="MSELQEASWYVVHTYSGHENKVKATIEKAVKTRGMEDCIRQVVV
                     PTEEVVETTKTGKEKTRQRKVYPSYVLVKMIITDESWYVVRNTKGVTGFVGPGSKPVP
                     LSEDEVKAMGIDTTDPKVVNSDIDFEIGDTVKVSQGPFSGQIGNIEEIDLENREVKVC
                     INAFGKRTLFVIELEGIEKI"
     gene            1616..2041
                     /gene="rplK"
                     /locus_tag="KR231_003113"
     CDS             1616..2041
                     /gene="rplK"
                     /locus_tag="KR231_003113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012158357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11"
                     /protein_id="HBH0005468.1"
                     /translation="MAKKVIGQIKLQIPAGKATPAPPVGPALGQHGVNIMGFTKEFNA
                     KTADQAGMIIPVVITVYQDRSFSFITKTPPAAVLIKKALNLKSGSGEPNKKKVAKMTS
                     AQVREIAELKMPDLNAASVEAAMSMIAGTARSMGVVIED"
     gene            2112..2810
                     /gene="rplA"
                     /locus_tag="KR231_003114"
     CDS             2112..2810
                     /gene="rplA"
                     /locus_tag="KR231_003114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L1"
                     /protein_id="HBH0005469.1"
                     /translation="MAKKGKRYAGALQKVDRTKFYDASEALTLVSDIAGAKFDETVEA
                     HIKLGVDSRHADQQVRGAVVLPHGTGKTKRVLVFAKGEKAKEAEQAGADFVGAEELVQ
                     KIQGENWFDFDIVVATPDMMGVVGRLGRVLGPKGLMPNPKSGTVTFDVAKAIDEIKAG
                     KVEYRLDKTNIIHVPVGKVSFGGEKLTENFTALMDAIIKAKPAAAKGQYLRSITVASS
                     MGPGVKINPARTAE"
     misc_feature    2862..2990
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00557"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L10 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00557"
     gene            3033..3539
                     /locus_tag="KR231_003115"
     CDS             3033..3539
                     /locus_tag="KR231_003115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L10"
                     /protein_id="HBH0005470.1"
                     /translation="MRKAIEIKSEVVSEIVEKLQKSSAAVVVDYKGLTVEEVTELRKQ
                     MREAGVDYKVYKNTLVRRAAKEVGIEQFNDELLVGTNAIAFGYDDPVAPARILKGFMD
                     SHPKMKLKMGIVEGAFYDESKIVEMANIPSREVLIAKLLGSLKAPVSNFAYLIDAIAK
                     KAEGQEEA"
     gene            3597..3962
                     /gene="rplL"
                     /locus_tag="KR231_003116"
     CDS             3597..3962
                     /gene="rplL"
                     /locus_tag="KR231_003116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000159736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L7/L12"
                     /protein_id="HBH0005471.1"
                     /translation="MTIEQILEAIENMKVLELNELVKAAEEKFGVSASAPVMVAGAAA
                     GGPAAEEKTEFDVVLTDVGSSKVGVIKAVREITGLGLKEAKEVVDNAPKTVKEGASKE
                     EADQIKEKLEAAGAKVEVK"
     gene            4354..5142
                     /locus_tag="KR231_003117"
     CDS             4354..5142
                     /locus_tag="KR231_003117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HBH0005472.1"
                     /translation="MEKLQGKIAVVTAATKGIGLASAEILAKNGATVYLAARSEELAN
                     EVINKISAEGGCAKFVYFNAREEETFTSMIEEVVKKEGKIDILVNNFGSTNPSLDKDL
                     VTGDTDNFFDTVNTNLKSVYLPCKAAIPHMIKNGKGSIVNISSIGSVLPDLSRIAYCV
                     SKAAINSLTQNIATQYAKDNVRCNAVLPGLIATKAALDNMSPEFIKEFLKHVPLNRIG
                     EPDDIAKAVLFYASDDSSFITGDLLEVAGGFGLPTPQFADNILG"
     gene            5613..9329
                     /locus_tag="KR231_003118"
     CDS             5613..9329
                     /locus_tag="KR231_003118"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HBH0005473.1"
                     /translation="MPHPVTIGKRTRMSFSKIKEIADVPNLIEIQVDSYEWFLKEGLK
                     EVFDDISPIEDYTGNLILEFVDYSLDDKPKYDIEECKERDATYCAPLKVKVRLINKET
                     GEIKEQEVFMGDFPLMTERGTFVINGAERVIVSQLVRSPGVYYAEERDKTGKRLISST
                     VIPNRGAWLEYETDSNDVISVRVDRTRKQPVTVLLRALGIGTDAEIIDLLGEDERLSA
                     TLEKDNTKTVEEGLVEIYKKLRPGEPPTVESASSLLNALFFDPKRYDLAKVGRYKFNK
                     KLALCYRIMNKISAEDIINPETGEVFVKAGEKISYDLAKAIQNAGINVVNLLMDDDKK
                     VRVIGNNFVDIKSHIDFDIDDLNIKEKVHYPTLKEILDGYSDEEEIKEAIKSRIKELI
                     PKHILLDDIIASISYEFNIFYNIGNIDDIDHLGNRRIRSVGELLQNQVRIGLSRMERV
                     IKERMTVQDMEAITPQALVNIRPVSAAIKEFFGSSQLSQFMDQTNPLSELTHKRRLSA
                     LGPGGLSRERAGFEVRDVHHSHYGRMCPIETPEGPNIGLINSLGTYAKINEFGFIESP
                     YRKFDKETSTVTDEIHYLTADEEDLFVRAQANEPLTEDGKFVNHRVVCRTVNGAVEMV
                     PESRVDYMDISPKQVVSVATAMIPFLENDDANRALMGANMQRQAVPLVRREAPIIGTG
                     IEYRAAKDSGAVVVARNSGIAERVTADEIIIKREDGNRDRYNLLKFKRSNSGTCINQT
                     PIINKGDQIVKGDVIADGPATDLGEVALGRNCLIAFMTWEGYNYEDAILINERLVKED
                     RLSTIHIEEYECEARDTKLGPEEITRDIPNVGDSAIKNLDDRGIIRIGAEVDSGDILV
                     GKVTPKGETELTAEERLLRAIFGEKAREVRDTSLKVPHGESGIIVDVKVFTRENGDDL
                     SPGVNELVRCYIAKKRKIKVGDKMAGRHGNKGVISRVLPEEDMPFMENGTPLDIILNP
                     QGIPSRMNIGQVLEVHLGLAAKTLGWYVATSVFDGANEYDIMDALEEAGYPRDGKLTL
                     YDGRTGESFDNRITVGYMYYLKLHHLVDEKLHARSTGPYSLVTQQPLGGKAQFGGQRF
                     GEMEVWALEAYGAAHILQEILTVKSDDVVGRVRTYEAIVKGENIPEPGIPESFKVLIK
                     ELQSLCLDVKVLTDEDQEIEVRESVDEDDTIGEFELDVVNHMGEVEESNIIEEIEDDF
                     AENAEDEDIENLEEFTEDDLFEEEIDFDSDDFDM"
     gene            9371..12856
                     /gene="rpoC"
                     /locus_tag="KR231_003119"
     CDS             9371..12856
                     /gene="rpoC"
                     /locus_tag="KR231_003119"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta'"
                     /protein_id="HBH0005474.1"
                     /translation="MFELNNFESIKIALASPEKIRQWSRGEVKKPETINYRTLKPEKD
                     GLFCERIFGPQKDWECHCGKYRRVRYKGVVCDRCGVEVTKSKVRRERMGHIELAAPMS
                     HIWYFKGIPSRMGLLLDMSPRSLEKILYFASYVVVDPGETGLNEKQLLTEKEYRTALE
                     KYGYTFTVGMGAEAVKTLLQNIDLEQQSKDLRAELKDSTGQKKVRTIRRLEVVEAFKK
                     SGNKPEWMILDAIPVIPPDLRPMVQLDGGRFATSDLNDLYRRVINRNNRLKRLLELGA
                     PDIIVRNEKRMLQEAVDALIDNGRRGRPVTGPGNRPLKSLSDMLKGKQGRFRQNLLGK
                     RVDYSGRSVIVVGPELKFYQCGLPKKMALELFKPFVMDKLVKEGYAHNIKSAKSIVEK
                     VKPEVWDVLEDVIKSHPVLLNRAPTLHRLGIQAFEPILVEGKAIKLHPLVCTAYNADF
                     DGDQMAVHVPLSVEAQAEARFLMLSVNNILAPKDGSPITTPSQDMVLGCYYLTIEAQD
                     GAKGTGMVFKDFNELLLAYYNKSVHLHALVKLKVTLEDGRSSLVESTVGRFIFNENIP
                     QDLGFVDRKENPFALEVDFLADKKSLGKIIDKCFRKHGNTETAELLDYIKALGFKYST
                     LGGITVAVDDMSVPEEKKVFIAEAEAKVDKYEKAYRRGLISDEERYEKVIETWTETTD
                     KVTDALMGGLDRLNNIYIMAHSGARGSKNQIRQLAGMRGLMANASGKTVEIPVKSNFR
                     EGLSVLEYFTSSHGARKGLADTAIRTAESGYLTRRLVDVSQDVIVREIDCGTEDTTEI
                     YAIKEGNEVIEEIYDRIVGRYTIDPILNPETGEVIVEADSMIQEDEAETIVALGIEKI
                     RIRTVLNCKTNHGVCSKCYGRNLATGKEVNIGEAVGIIAAQSIGEPGTQLTMRTFHTG
                     GVAGADITQGLPRVEELFEARKPKGLAVITEVSGRVEIDETGKRKEVNVIPEEGETQT
                     YVIPYGSRLKVKQGQMLEAGDPLTQGFINPHDIVRVNGVKGVQEYIVKEVQRVYRLQG
                     VDVNDKHIEVIVRQMLSKVKVEDPGDTDLLPGGYEDVLTFNECNKDAIDKGLRPAVAK
                     RVLLGITKASLATDSFLSAASFQETTRVLTEAAIKGKEDHLIGLKENVILGKLIPAGT
                     GMKKYRNIAVEKIED"
     gene            13145..13567
                     /gene="rpsL"
                     /locus_tag="KR231_003120"
     CDS             13145..13567
                     /gene="rpsL"
                     /locus_tag="KR231_003120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001142340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S12"
                     /protein_id="HBH0005475.1"
                     /translation="MPTINQLVRKSRKALEKKSTAPALQKGYNSLNKKVTDASAPQKR
                     GVCTSVKTVTPKKPNSALRKVARVRLTNGIEVSAYIPGEGHNLQEHSVVLIRGGRVKD
                     LPGVRYHILRGTLDTAGVDKRRQSRSKYGAKRPKEAKK"
     gene            13691..14161
                     /gene="rpsG"
                     /locus_tag="KR231_003121"
     CDS             13691..14161
                     /gene="rpsG"
                     /locus_tag="KR231_003121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001137493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S7"
                     /protein_id="HBH0005476.1"
                     /translation="MPRKGNIPKREVLPDPMYGSKVVTKLINNLMVDGKKGKSQRIVY
                     DAFAIVAEKTGEEALEVFNKAMDNIMPVLEVKARRVGGANYQVPIEVRPERRQTLGLR
                     WLVKYTRARGEKGMVEKLAKEIMDAANNTGASVKKKEDTHKMAEANKAFAHYRW"
     gene            14210..16276
                     /gene="fusA"
                     /locus_tag="KR231_003122"
     CDS             14210..16276
                     /gene="fusA"
                     /locus_tag="KR231_003122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor G"
                     /protein_id="HBH0005477.1"
                     /translation="MARKFPLERTRNIGIMAHIDAGKTTTTERILFYTGQTHKIGETH
                     EGASQMDWMEQEKERGITITSAATTASWKDHRINIIDTPGHVDFTVEVERSLRVLDGS
                     VAVFCAKGGVEPQSENVWRQAETYGVPRIAFVNKMDILGADFYNVVSMMKSRLNSNAV
                     PMQLPIGKEDSFIGIIDLLKMDAVIYKDDLGVEMEETDIPEDMKELAAEWREKLVESV
                     AETDEELMMKYLEGEELTIDELKVAIRKATIACEMNPVFCGTAYRNKGVQLVIDAVLD
                     YLPAPTDIPAIKGILADGEEAERHSSDEEPFSALAFKIMTDPFVGKLAFFRVYSGTLE
                     SGSYVLNATKNKRERIGRILQMHANTREEITKVYAGDIAAAVGLKDTTTGDTLCDPAN
                     PIILESMEFPEPVISVAIEPSSKAAQEKMGIALQKLAEEDPTFTVKTDQETGQTIISG
                     MGELHLEIIVDRLLREFKVEAKVGAPQVAYRETITQPVDVEYKYSKQSGGRGQYGHVK
                     IRVAPQEPGEGYKFTNKTVGGSVPKEYVGPVDMGIQGAMQSGIVAGYPVVDVAVELYD
                     GSYHEVDSSEMAFKMAGSMAFKDAMKKGNAVLLEPYFKVEVVTPEDYMGDVMGDLNSR
                     RGLIQGMEARSGAQVINAFVPLSEMFGYSTDLRSSTQGRATYTMIFDHYEQVPASVAK
                     KIAEGK"
BASE COUNT         6411 a         2033 c         3339 g         4567 t
ORIGIN      
        1 gataatatag gagcattatt aagaggagta caaagaaacg agatagaaag aggacaagta
       61 ctagcaaaga ctggatcagt aaaggcacac acaaagttta cagcagaagt atatgtactt
      121 aaaaaagaag agggtggaag acatacacca ttctttgatg gatatagacc acaattctat
      181 ttcagaacaa cagacgtaac aggagcttgt aagttaccag aaggaataga gatggtaatg
      241 cctggagata acgtaacaat ggaagtagac ttaataaact caatagttgt agaagaggga
      301 ttaagattct caataagaga aggtggaaga acagtagctt caggagttgt tgctacaata
      361 atagagtaat tctttactaa actgatggat taaaaggaat aacaaaaaga ggggttatgc
      421 tcctcttttt ttaacataga aatacaaaaa cattgacaca gcataggatt ttgtgataac
      481 ttatacaagg taatgattat aggaagttaa taatatcttg aatactgtag atttttaata
      541 aatacatatt ttaaagatat tatattcaca tatattaaca atatatatta ttgtattaca
      601 aagttggagg tgtatcagat gagagttaaa gtaactttag catgtacaga gtgtaagcaa
      661 agaaactaca acactactaa gaataagaaa aataatccag acagaataga attacaaaaa
      721 tattgtagat tctgtaaaaa gcatacaact cataaagaaa caaaatagtt ttttataagg
      781 atgtgagtat ggaatggctg cccaaaaaaa tgacggtgca aaaactaaaa aaaggtttag
      841 tttgtttgga tacttaaaag aaactaaaca agaattaaaa agagttacat ggccgacaaa
      901 aaaggaactg tttaaaaaca caagtatagt tttaactgta gttatttcat gcactatatt
      961 agtatggggt atagacacta tattatctgg tgcactagcg ttattactaa aatagacgaa
     1021 aagaggtaag ttaaatgtca gaattacaag aagcaagttg gtatgtagtt catacctatt
     1081 cgggacatga aaataaagtt aaagctacaa ttgagaaagc agttaaaaca agaggtatgg
     1141 aagactgcat aagacaagta gttgttccaa cagaagaagt agtggaaact actaaaactg
     1201 gaaaagaaaa aactagacaa cgtaaagttt atccaagtta tgttttggtt aaaatgataa
     1261 taactgatga atcttggtat gtagtaagaa atactaaggg agttacaggt ttcgttggac
     1321 ctggttcaaa accagtgcca ttaagtgaag acgaagtcaa agctatgggg atagacacaa
     1381 cagaccctaa agtagtaaat agcgatattg attttgaaat aggagataca gtaaaagtat
     1441 ctcaaggacc atttagtgga caaataggta acatagaaga aattgactta gaaaatagag
     1501 aagtcaaagt atgcataaat gcatttggta aaaggactct atttgtaata gagcttgaag
     1561 gtatagaaaa aatctaatac tatattatag aaaaatctga ggaggtgcgc tcaaaatggc
     1621 taaaaaagtt ataggtcaaa taaaattaca aatacctgca ggaaaggcta ctccagcgcc
     1681 accagttgga ccagcattag gacaacatgg tgttaatata atgggattca caaaagaatt
     1741 taatgctaaa actgcagatc aagctggaat gataatacca gttgttataa ctgtatatca
     1801 agatagatca ttcagtttta taacaaaaac tccaccagct gcagttttaa ttaaaaaagc
     1861 attaaactta aaatcaggtt ctggagaacc aaacaagaaa aaagttgcta aaatgacttc
     1921 agctcaagta agagaaatag ctgaattaaa gatgcctgac ttaaatgctg catcagtaga
     1981 agctgctatg agtatgatag ctggtactgc tagaagcatg ggtgttgtaa tcgaagacta
     2041 gttaaaagat acactttttt ttataaagtg ggaggctaga agccgaaatt aaccacgagg
     2101 aggaaaataa aatggctaaa aaaggtaaaa gatatgcagg tgcattacaa aaagtagata
     2161 gaactaaatt ttatgatgca tcagaagcat taacattagt ttcagatata gctggagcta
     2221 aatttgatga gacagtagaa gcacacatta aattaggtgt tgactcaaga catgctgacc
     2281 aacaagtaag aggtgcagtt gtattacctc atggaactgg taaaacaaaa agagttttag
     2341 tttttgctaa aggtgaaaaa gctaaagaag ctgaacaagc tggtgctgac tttgtaggag
     2401 ctgaagaatt agttcaaaaa atacaaggtg aaaactggtt tgactttgat atagtagttg
     2461 ctactccaga tatgatgggt gtagtaggta gattaggtag agtattagga cctaaaggtt
     2521 taatgccaaa ccctaaatca ggaacagtta catttgatgt agctaaagct atagatgaaa
     2581 taaaagctgg taaagttgaa tacagattag acaaaactaa cataatacac gttccagtag
     2641 gaaaagtatc atttggtgga gaaaaattaa ctgaaaactt tactgcatta atggatgcta
     2701 taataaaagc taaaccagct gctgctaaag gacaatattt aagaagtata acagtagctt
     2761 cttcaatggg acctggagtt aaaataaacc cagcaagaac agctgaataa taaaactgtt
     2821 gacacaggtt gacaaaaatg ttattatatc acttgtcaat gtaaaaaaga atagatttgc
     2881 cgtagatagt gggtgcgaaa gcttaatatc ccgccgaggt tttagataaa ttgagattac
     2941 taaagctttt gatgtctact tttggcaaca aaagcttttt ataatgttgc ggtaaatact
     3001 aagcctattt ggtgaaggag gtgcacatct atatgagaaa agctatagaa attaaatcag
     3061 aagttgtttc tgagatagtt gaaaagttac aaaaatcttc tgctgctgtt gttgtagatt
     3121 acaaaggatt aacagttgaa gaagtaactg agttaagaaa acaaatgaga gaagctggtg
     3181 tagattacaa agtatacaaa aatactttag ttagaagagc agctaaagaa gttggtatag
     3241 agcaatttaa tgatgaatta ttagttggaa ctaatgccat agcatttgga tatgatgatc
     3301 cagttgctcc agctagaata ttaaaaggat tcatggattc tcatccaaaa atgaaattaa
     3361 agatgggtat tgtggaaggt gcattctatg atgaatctaa gattgttgaa atggctaaca
     3421 taccatcaag agaagttctt atcgctaaat tacttggtag cttaaaagct ccagtatcaa
     3481 acttcgcata cttaatagat gcaatagcga aaaaggcaga aggtcaagaa gaagcttaat
     3541 tgcttaacta aaaaattata aatattaatt tgaaataaaa ttcggaggtg ctaaaaatga
     3601 caatagaaca aatattagaa gctatagaaa atatgaaagt tttagaatta aatgaattag
     3661 ttaaagctgc tgaagaaaaa ttcggtgtat cagcttcagc tccagtaatg gtagctggtg
     3721 cagctgctgg tggaccagct gctgaagaaa aaactgagtt tgatgtagta ttaactgacg
     3781 ttggttcttc aaaagttgga gttataaaag cagttagaga aataacagga ttaggattaa
     3841 aagaagctaa agaagtagtt gacaatgctc ctaagacagt taaagaagga gcttctaaag
     3901 aagaagctga tcaaataaaa gagaaattag aagctgctgg agctaaagta gaagttaagt
     3961 agtttcttta aaaagatacc cattgggtat ctttttttat ttataaaaaa ctataaagaa
     4021 agtatttgga attataaaga aagtattttt ataaaataaa aaaaatttat ataatagtac
     4081 taaattaagg gtatcatata tggtgtaatg gtattttaat ttaacattat tatcaaatta
     4141 aaatataaac aattgttgta atgtctatat ataaagtata taattaaact aaaatgtaaa
     4201 attttacatt ttagtttaaa aaaatacacg aatgttttat aaataaaatg taataaataa
     4261 ttaattaaca aatataaatt ttaaaataag ttagatattt agaaaaatcg aaatttgtag
     4321 gatttaaagg acatattcaa ggaggagtta ataatggaaa aattacaagg aaaaattgca
     4381 gtagttactg cagcaacaaa aggtattgga ttagcatcag cagagatatt agcaaaaaat
     4441 ggagcaactg tgtacttagc agctcgttca gaagaattag ctaatgaagt tataaataaa
     4501 ataagtgcag aaggtggttg tgctaagttt gtttacttta atgctcgtga agaagagacc
     4561 tttacctcaa tgatagaaga ggtagttaaa aaagaaggta agatagatat acttgtaaac
     4621 aattttggtt caacaaaccc ttctcttgac aaagaccttg taactgggga tacagataat
     4681 ttctttgaca cagtaaatac taatttaaaa agtgtgtatt taccatgtaa agcagcaatt
     4741 cctcatatga taaagaatgg aaaaggaagt atagtaaata tatcaagtat aggttcagta
     4801 ttacctgatt tatctagaat agcttactgt gtatcaaaag cagcaatcaa ctcattaact
     4861 caaaatatag ctacacaata tgctaaagac aatgttagat gtaatgctgt acttccaggg
     4921 cttattgcaa ctaaagcagc attagacaat atgtctccag agttcataaa agaattttta
     4981 aagcatgttc ctttaaatcg tataggggaa ccagatgata tagcaaaagc tgttctattc
     5041 tatgctagtg atgactcatc atttataaca ggggatttac ttgaagttgc aggaggattt
     5101 ggtttaccta ctccacaatt tgcagataat atattaggat aattaaatta ctaatatgca
     5161 atgaaagctt atgcattagt tatagtagaa atgatatttt tataaaggcc atagatataa
     5221 tttatattgg aaaggtttga ggttcaaaat tccaagttaa atttatttat ggtctttatt
     5281 ttgtatattt taataaattg tatatatttg tataaatgta attatttaca atcattttaa
     5341 tatggaatta taattaaata ggggggatgg tacttgtata aaatttttta tagaaaatta
     5401 gacctataaa tgaaaaatat ggattttata ttggaaaatt gtacataata cataatatat
     5461 gcttaaaata atttacaaaa aatcaaaaat aatgcatagt ttacatataa gataaaaaat
     5521 atattgaaaa atacttgaca ttatgctaaa attattagat gcgttagaat gaactattgt
     5581 tttattttta attattgaga ggtgaaaagt gaatgccaca tcctgtcacg ataggtaaaa
     5641 gaactagaat gagcttttct aaaattaagg aaatagctga tgtgccaaat cttatagaaa
     5701 ttcaagtaga ttcctatgag tggtttttaa aagaaggttt aaaagaagtg tttgatgata
     5761 tttcaccaat agaagattat actggtaatc ttatattgga atttgtcgac tattctctag
     5821 atgataaacc aaagtacgat atagaagagt gtaaagagag agatgctaca tattgtgcac
     5881 ctctaaaggt taaggtaaga cttataaata aagaaacagg tgagataaaa gaacaagaag
     5941 tgtttatggg tgacttccct ttaatgacag aaagaggaac tttcgttata aatggagcag
     6001 aaagagttat agtaagtcaa ttagttagat ctcctggtgt ttactatgcg gaagaaagag
     6061 ataaaacagg taagagattg atttcatcta ctgtaattcc taatagagga gcatggttag
     6121 aatatgaaac agattctaat gatgtaatat ctgtaagagt tgatagaaca agaaaacaac
     6181 cagttacagt tttacttaga gctttaggaa taggaacaga tgcagagata attgaccttt
     6241 taggagaaga tgagagatta tctgctacat tagaaaaaga taatactaag acagtagaag
     6301 aaggtcttgt agagatatac aaaaaattaa gaccaggtga acctcctact gtagaaagtg
     6361 catcatcttt attaaatgct ttattctttg acccaaaaag atatgaccta gcaaaagttg
     6421 gtagatataa attcaataag aaacttgctt tatgttacag aataatgaat aaaatttcag
     6481 cagaagacat aataaatcca gaaactggag aagtatttgt aaaagctgga gaaaaaataa
     6541 gctatgattt ggctaaagcc atacaaaatg caggtataaa tgtagtaaat ctactaatgg
     6601 atgatgataa aaaagttaga gttataggaa ataattttgt ggatattaag tctcacattg
     6661 attttgacat agatgattta aacataaaag aaaaagtaca ttatccaact ttaaaagaaa
     6721 ttttagatgg atatagtgat gaagaagaaa taaaagaggc tataaaatca agaattaaag
     6781 aacttatacc aaaacatata ttattagatg atataatagc ttcaataagt tatgagttca
     6841 atatattcta taatatagga aatattgatg atatagatca cctaggaaac agaagaataa
     6901 gatctgtagg tgaattgtta caaaatcaag ttagaattgg tctttcaaga atggaaagag
     6961 ttataaaaga aagaatgacg gttcaagata tggaagctat aacgcctcaa gcgttagtta
     7021 acataagacc agtttcagct gcaataaaag aattttttgg tagttctcag ttatctcagt
     7081 tcatggatca aacaaatcct ctatctgagt taacgcataa gagaagatta tcagcccttg
     7141 ggcctggagg tctttcaaga gaaagagctg gattcgaagt gcgtgacgtt caccattcac
     7201 actatggtag aatgtgtcca atagagactc cagagggacc aaatatcggt cttataaact
     7261 ctctaggaac ttatgcaaaa ataaatgaat ttggatttat agaatcacca tatagaaaat
     7321 ttgataaaga aacatcaaca gttactgatg aaatacatta tttaactgct gacgaagaag
     7381 atttattcgt aagagctcag gcaaatgagc cattaacaga agatggtaaa ttcgtaaacc
     7441 atagagttgt ttgtagaact gtaaatggtg ctgttgaaat ggttcctgaa agtagagtag
     7501 attacatgga tatatctcct aagcaggttg tatctgttgc cactgctatg atacctttct
     7561 tagaaaatga tgatgccaac cgtgccctta tgggagcgaa catgcagcgt caggcagtgc
     7621 ctctagttag aagagaagca ccaattatag gaactggtat agaatacaga gcagcaaaag
     7681 actctggagc agttgttgtt gctagaaatt ctggtatagc agaaagagta acagcagatg
     7741 aaataattat aaaaagagaa gatggaaaca gagatagata taatctactt aagtttaaac
     7801 gttcaaactc aggtacttgt ataaatcaaa cacctataat aaataagggt gaccagatag
     7861 taaaaggtga tgttatagca gatggtccag caactgattt aggagaagtt gcacttggaa
     7921 gaaactgtct tatagcattc atgacttggg aaggttataa ctacgaggat gctatattaa
     7981 taaatgaaag attagttaaa gaagatagat tatcaacaat tcatatagaa gaatatgaat
     8041 gtgaagctag agatacaaaa ctagggccag aggaaataac tagagatata cctaatgttg
     8101 gagatagtgc aattaagaac ttagatgaca gaggtataat aagaataggt gcagaagtag
     8161 actcaggtga tatattagtt ggtaaagtaa ctccaaaagg agaaactgaa cttactgctg
     8221 aggaaagatt acttcgtgca atatttggag aaaaggctag agaagttaga gatacttcac
     8281 ttaaagtgcc tcatggtgaa tctggtataa tagttgatgt aaaagtattt actagagaaa
     8341 atggagatga tttatctcca ggagtaaatg aattagtaag atgctatata gctaaaaaga
     8401 gaaaaataaa agttggagat aaaatggctg gtcgtcatgg taataaaggg gttatctcaa
     8461 gagtattacc tgaagaagat atgccattca tggaaaatgg aacaccacta gacataatac
     8521 ttaacccaca aggtatacca tcacgtatga acattggtca ggttttagaa gttcatttag
     8581 gacttgctgc taagacatta ggatggtatg tagcaacatc agtattcgat ggtgctaatg
     8641 agtatgacat aatggatgct cttgaagaag ctgggtatcc tagagatggt aaattaactt
     8701 tatatgatgg tagaacaggt gagtcttttg acaacagaat aactgttgga tatatgtact
     8761 acttgaaact acatcactta gtagatgaaa aactacatgc aagaagtact ggaccatact
     8821 cattagttac tcaacagcca ctaggtggta aagcacaatt tggtggacaa agatttggag
     8881 agatggaggt ttgggctctg gaagcatatg gagctgctca catacttcaa gaaatactta
     8941 ctgttaagtc tgatgacgtt gtaggtcgtg ttagaacata tgaagctata gttaaaggtg
     9001 aaaatatacc tgaaccagga atcccagaat catttaaggt tcttataaaa gaacttcaaa
     9061 gtttatgctt agatgtaaaa gtattgacag atgaagacca agaaatagaa gtaagagaat
     9121 ctgtggatga agatgataca ataggtgaat ttgagctaga tgttgtaaat catatgggag
     9181 aagttgaaga aagtaatata atagaagaaa ttgaagatga ttttgcagaa aatgcagaag
     9241 atgaggatat agagaattta gaagaattca ctgaagatga tttatttgaa gaagaaatag
     9301 attttgatag tgatgacttt gatatgtaaa tttaattaat gtaaatctca aatagaaggg
     9361 agagaactcc ttgtttgaat taaacaattt cgagtcgata aaaatagcat tggcttctcc
     9421 agaaaaaata agacaatggt ctaggggaga agttaaaaag ccagaaacta taaattaccg
     9481 tactttaaaa ccagaaaaag atggtctttt ctgtgaaaga atatttggac cacaaaaaga
     9541 ctgggagtgc cactgtggta aatatagaag agttagatat aaaggtgtag tttgtgatag
     9601 atgtggagta gaagtaacta aatcaaaagt aagaagagag agaatgggac atatagagct
     9661 agcggctcct atgtctcaca tctggtactt caaaggtata ccaagtagaa tgggactttt
     9721 acttgatatg tcaccaagat cgttagaaaa aatattatac tttgcctcat atgtggtagt
     9781 tgatccagga gagactggat taaatgaaaa acaattgctt acagaaaaag aatacagaac
     9841 tgctcttgaa aagtatggat atacttttac tgtaggaatg ggtgctgaag ctgtaaagac
     9901 attactacaa aatatagatt tagagcaaca aagtaaagac ctaagagcgg agttaaaaga
     9961 tagtacaggg caaaagaaag ttagaacaat aagaagatta gaagttgtag aggcatttaa
    10021 aaagtctgga aataaaccag aatggatgat tttagatgca ataccagtaa taccaccaga
    10081 tttaagacca atggtacaac ttgatggtgg aagatttgcg acttcagacc taaatgattt
    10141 atatagaaga gttataaata gaaacaatag acttaaaaga ttattagagc ttggagctcc
    10201 agatataatt gtaagaaatg aaaaaagaat gcttcaagaa gctgttgatg cattgataga
    10261 taatggtaga agaggtagac ctgtaacagg acctggaaat agaccactta aatctttatc
    10321 agatatgtta aaaggtaagc aaggtcgttt ccgtcaaaac ttacttggta agcgtgttga
    10381 ctactcagga cgttctgtta tagttgttgg accagaactt aaattttatc aatgtggact
    10441 tccaaagaag atggcattag aattattcaa gccatttgtt atggataaat tagttaaaga
    10501 aggttatgca cataatataa aaagtgcgaa atctatagta gaaaaagtta agccagaagt
    10561 ttgggatgtt ttagaagatg ttataaaaag tcatccagtt cttcttaacc gtgcaccgac
    10621 tctacataga ttaggtatac aagcatttga accaatctta gttgaaggta aggctataaa
    10681 actacatcct cttgtatgta cagcttataa tgcagacttt gatggtgacc aaatggcagt
    10741 tcatgtacct ttatcagtag aagcacaagc agaagcaaga ttcttaatgc tttctgtaaa
    10801 taatatactt gctcctaaag atggttcacc tataactact ccatctcagg atatggtttt
    10861 aggttgctat tatctaacaa tagaagccca agatggagct aaaggaacag gtatggtatt
    10921 taaagacttt aatgaactat tacttgctta ttacaataaa tcagttcatc tacatgcatt
    10981 agtgaaactt aaggtaacac ttgaagatgg aagaagttca ttggttgaaa gtactgttgg
    11041 tagatttata tttaatgaaa atatacctca agacttaggt tttgtagata gaaaagaaaa
    11101 tccatttgca cttgaagttg atttcttagc agataaaaaa tctcttggta aaataataga
    11161 taaatgcttt agaaaacacg gaaatacaga aacagctgaa ttactagatt atataaaagc
    11221 tctaggattt aaatattcta cattaggtgg cataacagtt gctgttgatg atatgagtgt
    11281 cccagaagaa aagaaagtat ttatagctga ggcagaagct aaagttgata agtatgaaaa
    11341 agcatacaga agaggtctaa tctctgatga agaaagatat gaaaaagtta tagagacatg
    11401 gacagaaaca actgataaag ttactgatgc tcttatgggt ggactagata gattaaataa
    11461 tatatatata atggcacatt caggagccag aggttctaaa aaccaaatta gacagctggc
    11521 aggtatgcgt ggtcttatgg caaatgcatc tggtaaaaca gttgagatac cagttaaatc
    11581 taatttccgt gaaggtttat cagtactaga atactttaca tcttcacatg gtgccagaaa
    11641 aggtcttgcc gatacagcta tacgtacagc tgaatctgga tatttaacaa gaagacttgt
    11701 tgatgtaagt caagatgtta ttgtaaggga aatagattgt ggaacagaag atactacaga
    11761 gatttatgct ataaaagaag gaaatgaagt tatagaagag atatatgata gaattgtagg
    11821 aagatatact atagacccta tattaaatcc tgaaactgga gaagttatag ttgaggctga
    11881 ttcaatgata caagaagatg aagcagaaac tatagtagct ttaggaattg aaaaaattag
    11941 gataagaaca gttcttaact gtaaaactaa tcatggagtt tgttctaagt gttatggtag
    12001 aaacttggca acaggaaaag aagttaatat aggtgaagca gttggtataa tagcagctca
    12061 atctatcggt gagccgggta ctcagcttac aatgcgtaca ttccatactg gaggagttgc
    12121 aggagctgat ataactcaag gtctaccaag ggttgaagaa ttatttgaag ctagaaaacc
    12181 aaaaggatta gctgtaataa ctgaagtatc tggtagagtt gaaattgatg aaacaggaaa
    12241 gagaaaagaa gtaaatgtaa taccagaaga aggcgagact caaacatatg taattccata
    12301 tggttctaga ttaaaagtta agcaaggtca aatgctagag gctggagacc ctctaacaca
    12361 aggatttata aatcctcatg atatagtaag agtaaatggt gttaagggag ttcaagaata
    12421 tatagttaaa gaagttcaaa gagtgtatag acttcaaggg gttgatgtta atgataagca
    12481 tatagaagtt atagtaagac aaatgctatc taaagtaaaa gttgaagacc caggagatac
    12541 agatttattg ccaggtggat atgaagatgt attaacattc aatgaatgta ataaagatgc
    12601 tatagataaa ggtctaagac cagcagttgc taaaagagtt ttacttggta taactaaagc
    12661 atctcttgca actgattcat tcttatcagc agcttctttc caagaaacaa caagagtatt
    12721 aacagaggca gcaataaaag gtaaagaaga ccacttaata ggacttaaag aaaatgttat
    12781 attaggtaag ttaataccag caggaacagg aatgaagaaa tatagaaata tagctgttga
    12841 aaaaattgaa gattaatagc atatagagta aagaaatctt gacaaccatt atttgtggtg
    12901 ttaaaatagt aaagtgtgtt gtttaaaagt acactaaggg cttgaacaag ttcttagtga
    12961 cttttagatg gcaataaatg agaactaaaa agcatcaagc tagaaaagtg ctaatatcac
    13021 atatttatgt gttatagaca ttaaattgta agtaacgaat gttacaatca gtcagtatga
    13081 atattcatat tgatgtagtt ggcggtcact gataagatcg aaaatttgga aggaggtgca
    13141 gatgatgcca acaattaacc aattagttcg taaaagtaga aaagcgctag agaagaaatc
    13201 tactgctcca gcattacaaa aaggttacaa ctctttaaat aagaaagtaa ctgacgctag
    13261 tgccccacaa aaaagagggg tttgtacttc agtaaaaaca gttactccta agaagcctaa
    13321 ctcagcttta agaaaagttg ccagagttag attaactaat ggtatagaag tttctgctta
    13381 tataccagga gaaggacaca acttacaaga gcatagtgtt gttcttataa gaggaggaag
    13441 agtaaaagac cttccagggg ttagatacca tatactaaga ggtactctag atacagcagg
    13501 tgttgataag agaagacaat caagatctaa atacggtgcg aagagaccta aagaagctaa
    13561 aaagtaaaaa caattaatga ttgattatag ttcggtgctt taaatatata tatatttacg
    13621 gcatcacggc attaaatgat ttatgtcgag tacctatgat ttaagttaaa taattaagga
    13681 gggaagcgaa atgccaagaa aaggtaatat tccaaaaaga gaagttttac cagatcctat
    13741 gtatgggagt aaggtagtta ctaaattaat aaataatcta atggtagacg gaaaaaaagg
    13801 aaagtctcaa agaatagttt atgatgcttt cgcaattgtt gctgaaaaga caggagaaga
    13861 agctttagaa gtatttaata aagcaatgga taatataatg cctgttttag aagtaaaagc
    13921 aagaagagtt ggtggggcaa actaccaagt gccaatcgaa gttagacctg aaagaagaca
    13981 aacattaggt ttaagatggc tagtaaaata tactagagct cgtggagaaa aaggaatggt
    14041 tgaaaagcta gctaaagaga taatggacgc agctaacaac actggagctt cagttaagaa
    14101 aaaagaagat actcataaaa tggcagaagc taataaagca tttgctcatt acagatggta
    14161 ggatatatag atatcttata aaattgagga tatcataagg aggataacca tggctagaaa
    14221 gtttcctttg gaaagaacta ggaatatagg aatcatggct catatagatg caggaaaaac
    14281 tactactaca gaaagaatcc tgttttatac tgggcaaact cataaaatag gagaaactca
    14341 tgaaggagct tctcaaatgg actggatgga gcaagaaaag gaaagaggta taacaataac
    14401 ttctgccgct actactgctt catggaaaga ccatagaata aacataatag atactcctgg
    14461 acacgtggac ttcacagttg aggttgaaag atctctaaga gttcttgacg gttcagttgc
    14521 tgtattctgt gcaaaaggtg gggttgagcc tcaatcagaa aatgtatgga gacaagctga
    14581 aacttatgga gtacctagaa tagcttttgt aaataaaatg gatatattag gtgcagattt
    14641 ctacaatgtt gtaagcatga tgaaatctag attaaattct aatgcagttc ctatgcaatt
    14701 accaataggt aaagaagatt catttatagg tataatagac ttattaaaaa tggatgctgt
    14761 tatatacaaa gacgacctag gggttgaaat ggaagaaaca gatataccag aagatatgaa
    14821 agaattagct gctgagtgga gagaaaaatt agttgaatca gtagctgaaa ctgatgaaga
    14881 attaatgatg aaataccttg aaggtgaaga acttactata gatgaattaa aagttgctat
    14941 aagaaaagct actatagctt gtgaaatgaa cccagttttc tgtggtacag cttatagaaa
    15001 caaaggtgtt cagttagtaa tagatgcagt tttagattac ttaccagcgc caactgatat
    15061 accagctata aaaggtatat tagcagatgg agaagaagct gaaagacatt cttctgatga
    15121 agagccattc tctgcattag cattcaaaat aatgactgac ccattcgttg gaaaactagc
    15181 gttcttcaga gtttattctg gaacattaga atcaggttct tatgttttaa atgcaactaa
    15241 gaataagaga gaaagaattg gtcgtatatt acaaatgcat gctaatacaa gagaagaaat
    15301 aactaaagtg tatgctggag atatagcagc agcagtagga ttaaaagata ctactactgg
    15361 agacacatta tgtgaccctg ctaatccaat aatacttgaa tctatggaat tccctgagcc
    15421 agttatatct gttgctatag aaccaagttc taaagcagct caagaaaaaa tgggtatagc
    15481 tcttcaaaaa ttagctgaag aagacccaac tttcacagtt aagactgacc aagaaacagg
    15541 acaaactata atatctggta tgggtgaatt acacttagag ataatagtag atagattatt
    15601 aagagaattt aaagtagaag ctaaagttgg tgcaccacaa gttgcatata gagagactat
    15661 aactcaacca gttgatgttg aatacaagta ctctaagcaa tcaggtggta gaggacaata
    15721 cggtcacgtt aagattagag ttgctcctca agagccaggt gaaggataca aattcacaaa
    15781 caaaactgtt ggtggatcag taccaaaaga atatgttggt ccagttgaca tgggtataca
    15841 aggagctatg caatctggta tagttgctgg atatccagtt gtagacgttg ctgttgagtt
    15901 atatgatggt tcttaccatg aggttgactc ttctgagatg gcgtttaaga tggctggttc
    15961 aatggcattc aaagatgcta tgaagaaagg taatgcagtt cttttagagc cttacttcaa
    16021 agtagaagtt gttactccag aagattacat gggagatgtt atgggtgact taaactcaag
    16081 aagaggatta atccaaggta tggaagctag aagtggtgca caagttataa atgcattcgt
    16141 tccactttca gaaatgtttg gatactcaac agacctaaga tcttcaactc aaggtcgtgc
    16201 aacttacaca atgatattcg atcactatga gcaagttcca gcttcagttg ctaagaaaat
    16261 agctgaagga aaataattta aaaataatta ataatataaa tataaaaaat aatcagctag
    16321 atgagagata tctctcatct agcacaagat
//
LOCUS       DAEPHU010000085        16071 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 01A10CD0081
            SAMN05941466-rid12468953.denovo.085, whole genome shotgun sequence.
ACCESSION   DAEPHU010000085 DAEPHU010000000
VERSION     DAEPHU010000085.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941466
            Sequence Read Archive: SRR6291087
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 16071)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16071)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068158.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 22:43:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,892
            CDSs (total)                      :: 3,805
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 87
            rRNAs                             :: 8, 1, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 55
            CDSs (without protein)            :: 55
            Pseudo Genes (ambiguous residues) :: 0 of 55
            Pseudo Genes (frameshifted)       :: 21 of 55
            Pseudo Genes (incomplete)         :: 28 of 55
            Pseudo Genes (internal stop)      :: 16 of 55
            Pseudo Genes (multiple problems)  :: 8 of 55
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16071
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941466-rid12468953.denovo.085"
                     /strain="01A10CD0081"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            161..679
                     /locus_tag="KR231_003123"
                     /pseudo
     CDS             161..679
                     /locus_tag="KR231_003123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888399.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            1111..1365
                     /locus_tag="KR231_003124"
     CDS             1111..1365
                     /locus_tag="KR231_003124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0005478.1"
                     /translation="MENKDIKLTICIFAFVIGIIVLFCCIGLGQFNMDCIIKQNGGSI
                     ATEQYNIYLEQSISQYRNFGSILVLLGGIGILFDKSVRKY"
     gene            1401..1724
                     /locus_tag="KR231_003125"
     CDS             1401..1724
                     /locus_tag="KR231_003125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0005479.1"
                     /translation="MARDVFSVKMTPLEAQKMVEKNLEADLVSVDIYNLENNKSIIVT
                     IFEKYYARSNSDAGLVVICENTTGKTLVKITSTGSAIGLFQIDWGTGNNLIKRVKKIF
                     IDYII"
     gene            1998..2150
                     /locus_tag="KR231_003126"
     CDS             1998..2150
                     /locus_tag="KR231_003126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0005480.1"
                     /translation="MDNFLFNVLASVTASYIVYLISKLIKKVKSHSTAKSDLKIDINF
                     KYHRKK"
     gene            2344..3267
                     /locus_tag="KR231_003127"
     CDS             2344..3267
                     /locus_tag="KR231_003127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SHOCT domain-containing protein"
                     /protein_id="HBH0005481.1"
                     /translation="MVGAFVLPNYAIILSEMSNLWGNFIMWILVPIITIVLLIIAVSS
                     MQYILVMIAFLLIIYSFIEKKIVMGLVSVLFFTYSIYLCATWEDKSLIADNKVETVKA
                     QRETVEREKEMERRRIQEEVDKERYIEKHGMEISENDLKVKLEALVPQEYKGKKYELK
                     VGKFKRYSMYFDLTVQNEKFSNSEECKKFVKEIANDLKKIKISKAYFKFHSKDDGGIY
                     NSVYIDYFRNIQNNVDNVENLEFNEFELKTEEEEKREQEKIEQEKNSYNNYIQNRVVD
                     PLDRIKKLKELLDSGAITQEEYNKKKKELLE"
     repeat_region   3534..4214
                     /inference="COORDINATES: alignment:crt:1.2"
                     /inference="COORDINATES: alignment:pilercr:v1.02"
                     /rpt_family="CRISPR"
                     /rpt_type=direct
                     /rpt_unit_range=3535..3561
                     /rpt_unit_seq="ttttagattaactatatggaatgtaaa"
     gene            4406..4558
                     /locus_tag="KR231_003128"
     CDS             4406..4558
                     /locus_tag="KR231_003128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0005482.1"
                     /translation="MKNRRKDKRGFSVLLDKEKLDKFDEVLEEKNLTKKEWLEEKIDE
                     ELEQKE"
     gene            4678..5492
                     /locus_tag="KR231_003129"
                     /pseudo
     CDS             4678..5492
                     /locus_tag="KR231_003129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894376.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="toxin Bro"
     gene            5544..5705
                     /locus_tag="KR231_003130"
     CDS             5544..5705
                     /locus_tag="KR231_003130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0005483.1"
                     /translation="MCENLLDNMYIEKRKEEYRIKLLKIRETDIDIYNKLESIVYKLS
                     EKKLEKNNK"
     gene            complement(6034..6498)
                     /locus_tag="KR231_003131"
     CDS             complement(6034..6498)
                     /locus_tag="KR231_003131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0005484.1"
                     /translation="MDFGEVKSELSDKDLKDNEEALNKYKKYYLKVYKYYSEMDSIKS
                     IQDIEIEQSRLKGQLQKNSNPIFALYISIMAVVFSTTINLTFDLSDITNYFIRMIMTL
                     LFIVLLIFLVNKGILPIAIPYRNNIQFYTTALDVLEDMKKKILRERKYKKRR"
     gene            complement(6634..6951)
                     /locus_tag="KR231_003132"
     CDS             complement(6634..6951)
                     /locus_tag="KR231_003132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897465.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0005485.1"
                     /translation="MDFGNINLILIGIIVIIGTTIIYLIKPKTAFCSKKYFNKLESIY
                     GNIDKKKTVKLEVLYRYVTGLEYIAIGLFTRRLDITIIAIILVAIITTALYYLIRKKY
                     ITI"
     gene            complement(7234..7530)
                     /locus_tag="KR231_003133"
     CDS             complement(7234..7530)
                     /locus_tag="KR231_003133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0005486.1"
                     /translation="MYFKTYILKREVNNKQLEITRSFDLDNLICTATEILKDNEIDLI
                     ITNEVNNVVWRNEKSTPPARECLVIAIEVYWWYTSIFLLYHINYVIKKSYLNRF"
     gene            complement(7549..7962)
                     /locus_tag="KR231_003134"
     CDS             complement(7549..7962)
                     /locus_tag="KR231_003134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0005487.1"
                     /translation="MKVKSKRSFIVGIIVCMLCCASLVIYCILKDKRFLISSFLLIVI
                     AIFNFCNAFSRKGIVEELHDSADERDLYLTMKTSHILVKIMNYTLFTFTFLFIIAYSA
                     WKNQSLLVIAITLCVIEIFLFVAYLLINIFLEKKE"
     gene            complement(7946..8179)
                     /locus_tag="KR231_003135"
     CDS             complement(7946..8179)
                     /locus_tag="KR231_003135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBH0005488.1"
                     /translation="MKTKVREFRTNMGLTQQQLADLVHVSNRTIISIEKEQYSPSLML
                     AYRMAQVFGTTIEELCCLKENKEMEDKKHESKE"
     gene            8398..8772
                     /locus_tag="KR231_003136"
     CDS             8398..8772
                     /locus_tag="KR231_003136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
                     /protein_id="HBH0005489.1"
                     /translation="MKISKLPEAELKVMRYICEANKVLTSRELVAAMEEKYEWNESTT
                     FTVLKRLERREFLSTEKIGKLTHYNILVKEKKYLRFETKEFLKNIHKNSISSLMSALH
                     GEDDEVDEDKLSELEEYFKNLK"
     gene            9384..10076
                     /locus_tag="KR231_003137"
     CDS             9384..10076
                     /locus_tag="KR231_003137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBH0005490.1"
                     /translation="MYNILVVDDDKEIVDSIEIYLKSEGFKIYKAYDGMKALEIITEN
                     DIHLILMDIMMPKLDGIKATVKIREERNIPIILISAKSEDTDKIIGLNIGADDYITKP
                     FNLLELIARVKSNLRRYVTLGNYEDTCKEILKSGALELNTLTKEVKIDGENIKMTPIE
                     YKIIELLLENKGRVFSIDEIYEKVWNEESFNSENTVAVHIRRIREKIEINPKEPRFLK
                     VVWGVGYKIEKF"
     gene            10272..12332
                     /locus_tag="KR231_003138"
     CDS             10272..12332
                     /locus_tag="KR231_003138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HBH0005491.1"
                     /translation="MEKYRVLKLVSLIIISISFPLTILLVTIGLAEPKYNIQKTSTKS
                     GIFDISDDFYDSNIFDEGTMASLLPKFKLSVGGKLTSKEKGKFQQEGKSIDLSSSDSE
                     YDKIMINEQASEEYLSYLKNIKVYVINTYTGVFYTNTSYASLYDFKQKTKSYCNVEII
                     NKIGKSSYIKTINGEKFELNNLSLELNEVDEGFEAYVSFPEEPTIEDGIVYTNFQIFK
                     QATEKVRLFFVASLSLAIICLLSIILYIKIKGEVLKRNNVFLLIYSKIPMEFNVILVS
                     ISIAILTIYALAVSYHIDVIALVSLSLLIVSNNIFFINVQLSYLENKMCIFKTSIIVR
                     VILWLIKTVREVSNAIKKVSLARKVIVIVIISLALIMAISTRSIGMGLLFSICIFLGF
                     TIYITKRLSYLSYVIEGTERIKKGELDYKIKITGNDNFTSLAENINNIGEGLDRAIEE
                     QVKSERMKSDLITNVSHDLKTPLTSIINYVDLIKKEESIQPEYINDYINVLESKSKRL
                     KLLIEDLFEASRVSSGNIELQISKIDLVQLLRQSIGELEEKLSKNNLYLKLNVPNDKV
                     YIWADGRRMYRVFENLLSNIAKYSLEETRVYIDVYDYGENVKVTMKNISSYELNFDPS
                     EIMERFKRADESRNTEGSGLGLAIARDLVALQGGKFYIEIDGDLFKANLEFQKYEEEI
                     TNME"
     gene            complement(12538..12861)
                     /locus_tag="KR231_003139"
     CDS             complement(12538..12861)
                     /locus_tag="KR231_003139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlD domain-containing protein"
                     /protein_id="HBH0005492.1"
                     /translation="MNNNYIFFIIIGMYIVTYLPRVLPMLIFSKKEMPDFLKKIMKFI
                     PVAILTSLTAKDVFFNGDSLYLSIANPKIISFMIVLLVAYKFKSIGISIITGVISIYL
                     FGIIL"
     gene            complement(12854..13555)
                     /locus_tag="KR231_003140"
     CDS             complement(12854..13555)
                     /locus_tag="KR231_003140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlC family ABC transporter permease"
                     /protein_id="HBH0005493.1"
                     /translation="MERTQQLKESFIASIPIFLGYIPIGIVGGILLQKSGLSPFQIAL
                     MVTLVFGGSSQFIAASMISTGASVTSIVLTTFIVNLRHFLMSSNLNMYIKNKSPKFIL
                     PFCHTITDETFAVNYEKFTAGNWSDRNAIYLNFFCLISSVLANFIGAFLGESISIDSS
                     ISGFILTSMFIALIVSQIKNKIYIVVFISSIIISVILYALFKSNLVIIVASILASLIG
                     FFIEESYCKKEESYE"
     gene            complement(13833..15218)
                     /locus_tag="KR231_003141"
     CDS             complement(13833..15218)
                     /locus_tag="KR231_003141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HBH0005494.1"
                     /translation="MPINSFENYPMNWKPKRPSKGQILYKALVEQLEQDINNGFLLPG
                     TKLPPQRELADFLDVNVSTISRAFKICEKKGLISGVTGSGTFVSYDTRSNLFLMSSNN
                     KITFIEMGTMNPDFTLEEMNTLFKHIIKEIDFKTIFQYGQRDGAKWQKEAIAKLIYKA
                     GLETTSDSLLPASGGQNAIVAILAGLFQHGDRIGVDPLTYPGIKTAAKMLGIQLIPIK
                     QEDNEISEEGLLYACKNENIKGLYIIPDYQNPTTHIMSQNGRKMIANIASKYNLIVIE
                     DAIHSLLNETHLNPVASYLPNQTIYITSLSKIIAPSLRLAYISTPKQYREALSSALYN
                     INLSQSYFLTEIAYRMITSGEADKLINARRKSARRRNKIINQYLSGYNLLGNEECIFR
                     WLILPDGIMAEKFEIQALKEGVQVYASERFAVGKEKPISAIRIAVCATESTEELKAGL
                     SVLKRLLEEKK"
     gene            complement(15326..15469)
                     /locus_tag="KR231_003142"
     CDS             complement(15326..15469)
                     /locus_tag="KR231_003142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0005495.1"
                     /translation="MYDCDNQPKTPEEAVLYTRKRNFNIFKKTIPLYDKEGIKIIGRF
                     EIN"
     gene            complement(15664..>16071)
                     /locus_tag="KR231_003143"
     CDS             complement(15664..>16071)
                     /locus_tag="KR231_003143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3284 domain-containing protein"
                     /protein_id="HBH0005496.1"
                     /translation="TEVLLKYSAKDIFNIFTKSARLNFPNFNEKKAVGTFVQQKNNKR
                     FKVEITNFEKNRVYEIKTSNKRESTITRYELVHIDLENTKLIFIESESKRNIFGKINS
                     ALVRVLFGKRQPEEFNKFIKKLEMELENNSVNL"
BASE COUNT         6375 a         1757 c         2424 g         5515 t
ORIGIN      
        1 tttaatagaa tatgtatagt atatagtaga tagaatgtat aaaaataaaa actgttcaat
       61 aagaattaat atacattaat tcagctgaat ccaatcaaaa tacttaaata aaagtaatct
      121 gaaaataaca taattcaaat caatttattc aaataaacct caatttatct caaatcttaa
      181 gaagtcatta aacaaacttg ctaaattaca aagagaatta tcaagaaaaa caatcggtag
      241 tttaaataga aataaagcaa gattaaaagt tgcaagactt caagaacata tagctaatca
      301 aagaaatgat tttctacaaa aactatctac taaattaata aaagagaacg atattatttg
      361 catagaagat ttacaagtaa agaatatgat taggaatcgt aaactatctc gctcaatttc
      421 tgatgtgtca tggtcagagt ttattcgtca attagaatac aaggctaatt ggcatggtag
      481 acaaattgta aaggtgggta aattctttgc aagttcacaa atatgcaata aatgtgggta
      541 taaaaacgag gaagtgaagg acttaaatat aagagaatgg atttatccta gttgtaatga
      601 aactcacgat agagatataa atgcaagtat aaatatatta aaagaaggat taagactaat
      661 aacaattcaa aataaataac gtatgtaaga accgtaggaa ctacggggat agcctgtgga
      721 gaattagtaa gacatatgtt agtatgcaaa attctgtgaa gcaggaaacc tgtgacttta
      781 gtcatgggag gttcaggcta gtattactca ttattgtatt caaaagctaa agtggaaacc
      841 tagtgaatat atgaatttag aagttaatga gagagcatta gcagccgact caatacttat
      901 taaaattgaa gatgaagaag aaacaatgaa agaagctgaa agagagaaaa agagaggtag
      961 aagaaggtag aatttaaagt taaaatagtt acattgctaa tatatgaaaa tgttacaaat
     1021 ttggaaatag atggatatat atgttgtata gtataatgta gataatatat caccaagtaa
     1081 aaaacaacaa ataaatctaa attatgaggg gtggaaaata aagatattaa acttacaata
     1141 tgtatatttg cttttgtaat tggaataata gtgttatttt gctgtatagg tctaggtcaa
     1201 tttaatatgg attgtattat aaaacaaaat ggtgggtcaa tagctaccga acaatacaac
     1261 atatatttag aacaatctat ttcacaatat agaaattttg gttctatact ggttttacta
     1321 ggaggaatag gaatactgtt tgataaaagt gtcagaaaat actaaaaaag tatattttta
     1381 tttaggatgt gatgaatgat atggcaagag atgtatttag tgtaaagatg acaccactag
     1441 aagcacagaa aatggtagaa aaaaatttgg aagcagattt agtttctgtt gatatttata
     1501 acctagaaaa taataagtct ataatagtta caatctttga aaaatattat gcaagaagca
     1561 atagtgatgc aggtttggta gtgatttgtg aaaatactac aggaaaaaca cttgttaaaa
     1621 ttacctcaac tggtagtgca attggactat ttcagattga ttggggaaca ggtaataatt
     1681 tgattaaaag agtaaaaaaa atatttattg attatattat ttaattattt tatgtagata
     1741 ttcttaggtt ggtatggaat ttgtactaac ctattaagta atcaataaaa ctaaataaac
     1801 atagaaagca cttacaaata tgtaggtgct ttttattgaa aaaatagaaa ataaaataaa
     1861 aagtaagata taggaaaaat atgtaagaat tatatgttat aataattgta gcaagaagat
     1921 gtaatctaca atttatagag tggagttcat gtattaaaaa attatcctcc caacgataag
     1981 aagggaggtg aatatacatg gataattttt tatttaatgt gttagctagt gtaacagcta
     2041 gttacatagt ttatttgatt agcaagttaa tcaaaaaagt aaaaagccac tctaccgcaa
     2101 agagtgactt aaagattgat ataaatttta aatatcatcg taaaaaataa ctttcagtta
     2161 tagaacttca ctctaccgca aatagattgt agttcttctt gtttttatta taccacaaat
     2221 tagaaaaaat attgcatata atatttttta tagtcaataa aaatatgaaa ttttttatac
     2281 acaatgatga tgaatctaac tagatgaata aatttaattg taaataagaa agtacttact
     2341 taaatggtag gtgcttttgt tttgccaaat tatgctataa tattgagtga gatgagtaat
     2401 ttgtggggga attttataat gtggatatta gtaccaataa taacaatagt attacttata
     2461 atagctgttt cttctatgca atatatttta gttatgatag cttttttgtt gattatatat
     2521 tcttttatag aaaagaaaat agttatgggt cttgtgtcag ttcttttttt cacttattca
     2581 atttatcttt gtgcaacttg ggaagataaa tccttgatag cagataataa agttgagact
     2641 gttaaggcac aaagagaaac tgtagaaaga gaaaaagaaa tggaaagaag aagaatacaa
     2701 gaagaagtag acaaagaaag atatattgaa aaacatggaa tggaaatatc agaaaatgat
     2761 ttaaaagtta agctagaggc tttagtacct caagaatata aggggaagaa atatgaatta
     2821 aaagtaggaa aatttaaaag atatagtatg tattttgatt taactgtaca aaatgaaaaa
     2881 tttagtaatt ctgaagaatg taaaaaattt gtaaaagaaa ttgctaatga tcttaaaaaa
     2941 attaaaataa gcaaggcgta ctttaagttt cattcaaaag atgacggcgg tatatataat
     3001 tctgtttata ttgattattt tagaaacata caaaataatg tagataatgt tgaaaattta
     3061 gaattcaatg agtttgaact taaaaccgaa gaagaagaga agcgagaaca agagaaaata
     3121 gaacaagaaa aaaacagtta taataactac attcaaaaca gagtggttga cccactagat
     3181 agaataaaga aactaaaaga gttgctagat tcaggagcaa ttacacagga agaatataat
     3241 aaaaagaaaa aagaattatt agaatagata atatagtaag cacttacaag tatgtaggtg
     3301 cttttaaatt tacaaagtat tccattttaa ttttatagtt tagattttat gatataataa
     3361 aaatatagaa gttttgcagt gtgcgatatt tgttacaaag tagggcttaa tacttgaaat
     3421 ctaagatgtt gagggtgcgt gataagtgtt atcaattgca ctattgcccg ctcactgcaa
     3481 ttttaagagt attgtatata tgtaggtatt ggaaatgcta agtttatttt ggggttttag
     3541 attaactata tggaatgtaa aactgactcg ggagcatata ataagtaata tcaagaatag
     3601 ttttagatta actatatgga atgtaaaatt cgtaaaataa caattgtcag gaatatgaga
     3661 agtttgtttt agattaacta tatggaatgt aaaattggac tcaaaatata agttaaaaaa
     3721 atttttaagt tttagattaa ctatatggaa tgtaaaaatt tttgacgcta tgaagaaatt
     3781 tactacaaaa tttgttttag attaactata tggaatgtaa aaactttttt catcctccca
     3841 aacctcttgt tcgctgtcgt tttagattaa ctatatggaa tgtaaaaaag aaaataagtt
     3901 taaaaaaagg tttcattatt atatcgtttt agattaacta tatggaatgt aaaaccaatt
     3961 atgtacagtt tagttactgt gttaagtctt gttttagatt aactatatgg aatgtaaaat
     4021 ccttttataa atatcttctg acatgtgtat atgcttgttt tagattaact atatggaatg
     4081 taaatcggct acaacggtat aaattaaatt tagcagggta cattttagat taactatatg
     4141 gaatgtaaat tgctgtgatt tcaataataa aacaattaat aattgtgttt tagattaact
     4201 atgtggattc aaaattaaat aaacaaagaa agcacttaca aatatgtagg tgcttttatt
     4261 ctgctcaaaa ttggtcggtt gggtaaaata attagaaaaa gttagtaaaa acctattgac
     4321 tgtaactcgt tacaatattg ttattaatgt aacgagttac agaaaagagg tgaataaaat
     4381 agcaactaaa agtagggcag agtatatgaa aaatcgtcga aaagataaaa gaggttttag
     4441 tgtactttta gacaaagaaa agttagataa atttgatgaa gtgttagagg aaaagaatct
     4501 aaccaagaaa gaatggctag aagaaaaaat cgacgaggaa ctggaacaaa aggaataaaa
     4561 aataagggtc actcccaccg accaaagttt gagtaacccc tatgacgtat actatcgtat
     4621 atcaattata gtatatgtca ttccttaaaa aaatcaatta ttaaggagtg taatattatg
     4681 aaaaatgaat taatgatgtt tgaaggaaaa gagattgaag tatttgaatt tgaaggaaga
     4741 attttattca actcaaaaga tgtagtaaac tgtttagaca taaaaaatgt taatgagaat
     4801 ataagactta tgaatgaaaa gcaagttgta aagttaagaa attcggatat cagtaatact
     4861 gacatccgaa aacttaataa tgctggagaa aattttctta ctgaaagtgg agtgtataaa
     4921 ttaatcttta aatcaagaaa agaagaagct gagagattcc aaggctggat aagtgatgaa
     4981 gttttaccaa gcataagaca aactggtgca tacataaata ataatgcaat accgaaaagt
     5041 tgagagaaaa agcaagtgag attgaaaaat tacagttggt ttataacagt acatctatgt
     5101 taaaagaatt gctagatgat gcaggctttg acaataaatc aaaactatta acagctaaaa
     5161 cattatataa gaaagcagga attgatttac caatagagat aaacgaagaa gaacattatt
     5221 ttgatacaaa acaaatagca tctaaactga aaatatattc taagagtaat aaaccagctc
     5281 agatggcagt ttgtgagatt attaaaaaga ttgatttaga agatggtgaa gttaaaggtg
     5341 tttgggaaat taatggttct tggactggta ctgtaaataa atatacaaag agtgtaatag
     5401 ataaggtgag aacttggata gaggaaaata atagacctac caagattgca ggtgagaaga
     5461 agaattatta tgtattttac aaaattgagt aaatttatca gttgtattaa ataatttagt
     5521 ttagttttgg ggggattaat acaatgtgtg agaatttact tgataatatg tatattgaaa
     5581 agagaaaaga agaatataga attaaacttt tgaaaataag agaaacagat atagatatat
     5641 ataataagtt agaaagtata gtatataaac tttctgagaa aaaattagag aaaaataata
     5701 aatagacata taaagcactt ggatattcta ctgtttcaag tgctttgttt ggtataaaat
     5761 ggtataatgg agatagagaa ttatattaac ccaaaaatgg agaaaataga gaagatgatt
     5821 tagttgacgc tttatcagta ggagtacttg caggtaagac agaatctcta gtactattag
     5881 ttggaaatgg aataagtgat actcaaaaaa gtttaataaa taaaagagaa tttagaaata
     5941 taactcaaat tggtggaaat ggaaatgaga aagcatttag tgaagtagaa aacttagtta
     6001 aatagattag aaggtagcaa ctagagttgg ttgttacctt ctttttttat actttctctc
     6061 tctaagtatt ttctttttca tatcttctaa tacatctaat gcagtagtat aaaattgtat
     6121 attatttcta taaggtatag ctattggaag aatgcccttg ttaactaaaa aaataagaag
     6181 tacaataaat aaaagtgtca taatcattct aataaaataa ttagtgatat ctgataaatc
     6241 aaatgttaag ttaattgttg tagaaaatac aacagccata atagatatat acaaagcaaa
     6301 aatggggtta ctattttttt gtaactgtcc tttaagccta gattgctcta tttctatatc
     6361 ttgaatactt tttatggaat ccatttcact ataatactta taaactttta aataatattt
     6421 tttatacttg tttaaagctt cttcattatc tttaaggtct ttgtcactta actctgattt
     6481 aacttcccca aaatccataa aatccctcct acaatgttat ataatatact ttaatttata
     6541 gcatatttaa gaacttatat cagcaatttg tcgaacgatt ttagctaaaa atagagtata
     6601 atgataggct tattatttat aagatattat tttttatata gttatatatt tctttctaat
     6661 tagataatat aatgctgttg ttataatggc tactaatatt attgctatta ttgtaatatc
     6721 taatcttctt gtaaataagc ctattgctat atactcaaga cctgttacat agcgataaag
     6781 tacttctagt ttaacagttt ttttcttatc tatatttcca tatattgatt ctaatttatt
     6841 aaaatatttt ttactacaaa aagcagtttt aggtttaatt aaatatatta ttgtagttcc
     6901 tattataact attattccaa taagtataag attgatattt ccaaaatcca tagcagatac
     6961 ctcctattaa atttgctttt cttaatcaaa gtatatcagt aacacaagta caaagagcat
     7021 ctaaaatatt acaaatatta acaggataga taaaactata gtaaaaattg taataataaa
     7081 gcgaacgaaa attatcatac taaaacataa gacatgttat aattgtatta gatagaagat
     7141 taacatacac caaagcactc cttacaataa agagtgctta tttttttgaa attcatcaat
     7201 atataaacta tcaagaacct tattcaacac accttaaaat cgatttaaat agctcttttt
     7261 gataacataa tttatatgat ataataaaaa aatagaagtg taccaccaat acacttctat
     7321 agctataact aagcattctc ttgctggggg agtgcttttt tcatttctcc aaacaacatt
     7381 atttacttca ttagtaatta tcaaatcaat ctcattatct ttcaaaatct ctgttgcagt
     7441 acaaattaga ttatctaagt caaaacttcg agttatctct agttgtttgt tatttacttc
     7501 tctttttagt atataagttt taaaatacat ttatatcacc ccttgtattt actctttttt
     7561 ctctaaaaat atattgataa gtaaatatgc aacaaataaa aaaatctcaa tgacacatag
     7621 tgttatagct ataactagaa gtgattgatt tttccatgca ctataagcta tgatgaaaag
     7681 aaatgtaaaa gtaaataatg tataattcat aattttaact aagatatgac ttgttttcat
     7741 tgttaagtac aagtctcttt catctgcact atcgtgtaat tcttcaacaa tgccttttct
     7801 tgaaaaagca ttacaaaaat taaagattgc tattacaatt aaaagaaatg atgaaattag
     7861 gaatctttta tcttttaaaa tgcaataaat aactaaacta gcacaacata acatacaaac
     7921 tataataccc actataaaac ttcgtttact ctttactttc atgtttttta tcctccattt
     7981 ctttattttc ttttaaacaa catagttctt caatcgttgt accaaacact tgtgccatac
     8041 gataggcaag cataagagaa gggctatatt gctctttttc aatagaaata attgttctgt
     8101 ttgatacatg gactaaatca gcgagttgtt gctgtgttag acccatattt gttcgaaatt
     8161 ctcgtacttt tgttttcatt ccataacctc tttctatatg aagctaactt catgtgaagt
     8221 tagcttcata atatcctaaa atgagtaaaa tgtcaatctc attagataag tattataaaa
     8281 cctaaaagaa taatatggta aaaattggat ggaattattt accttaattc tcttgtttgt
     8341 aaaactttat tgatatagaa tttaacatat acataaatcg gcaaaggggc gcgaattatg
     8401 aaaattagta aattaccaga agcggaatta aaagttatga gatatatttg tgaagctaac
     8461 aaggtattaa cttctaggga attagttgct gcaatggaag aaaaatatga gtggaatgaa
     8521 tcaactacat ttacagtttt gaaaagatta gagcgaaggg agtttttaag tacagagaaa
     8581 ataggcaaac ttacacatta taatatacta gtaaaagaga aaaaatatct aaggtttgaa
     8641 acaaaggaat ttttgaagaa catacataaa aattcaattt caagtttaat gtcagcgtta
     8701 catggtgaag acgacgaagt ggatgaagat aaattaagtg aactcgaaga atattttaag
     8761 aatttgaaat aagaaaatga caaattgata cataataaat aaaatgaagg tatgaaatta
     8821 taactttttc taccttcatt ttgtttatta ttctgaacat gttaagaaaa tgaaataagt
     8881 ttgtatttta gttatataaa ttttaataga atatgtacag tatatagtag atagaatgta
     8941 taaaaataga atttaaataa gtagctatta ttgcagtgaa atgaatgttt ctaagtatat
     9001 ttgggtggaa gaatggtgga agaaaattag tgaaatgtaa ttcttccacc attcttccac
     9061 ccaaaaaata aaaactgttc aataagaatt aatatacatc aattcagctg aatgcaatca
     9121 aaatacttaa atgaaagtaa tctgaaaaca acataattca aatcaattta ttcaaataaa
     9181 cctcaattta tcttaaatct taagaaatat ttaagaatta ggataatatt ttcttaagat
     9241 ttatatttta ttatatagtt ataagggaaa gttacaaaaa tgtaagccaa agtaatataa
     9301 caatttagtc attgttgaga aagggagtga aagatattgt ataatataga taagtattat
     9361 tatacaatag aggaagtgaa aatatgtaca atatattagt agtagacgat gataaagaaa
     9421 ttgttgattc gatagaaata tatcttaaat cagaaggatt taaaatatat aaagcatatg
     9481 atggaatgaa agctttggaa ataataacag agaatgacat tcatctaata ctaatggata
     9541 taatgatgcc taaattagat ggaatcaaag caactgtaaa aatacgagaa gaaagaaata
     9601 ttccaataat tttaatttca gcaaaaagtg aagatacaga taaaataata ggattaaata
     9661 ttggagctga tgattatata acaaagccat ttaatctatt agagcttata gctagggtta
     9721 aatcaaactt aagacgatat gtaactttag gtaattatga agatacatgt aaagaaattc
     9781 taaaaagtgg agctttggag ttaaatacac taacaaaaga agttaaaatt gatggtgaaa
     9841 acataaaaat gactccaatt gagtataaaa taattgaact tcttttagaa aataaaggac
     9901 gagttttctc aatagatgag atatacgaaa aagtatggaa tgaggaaagt tttaattcag
     9961 aaaatacagt agcagtacat atcagacgaa taagagaaaa gattgaaata aatccaaaag
    10021 aaccaagatt tttaaaggtg gtgtggggag ttggttataa gattgaaaaa ttttagtgga
    10081 aaaattataa aagaaaagag tttaatattt aattgcattt tgattttagt catttttaca
    10141 tttacacaaa tgttaggaat tttaatatgt tttaattttt tctctgagag tttaatttac
    10201 tctatgggga ttatgctttt cttaaacttt attttatata aaatactgac aatgtagatg
    10261 aggtgggcaa cttggagaaa tatagagtat taaagttagt ttcattaatc ataatatcta
    10321 tctcatttcc attaactata ttgttggtga caataggact tgctgagcct aaatacaata
    10381 tacaaaaaac ttctacaaag agtgggattt ttgatatatc tgatgatttt tatgatagta
    10441 atatatttga cgaaggaaca atggcaagtc tattacccaa gtttaagcta tctgtaggtg
    10501 gtaaattaac tagtaaagaa aaaggtaaat tccaacaaga aggtaaaagt atagatttaa
    10561 gtagtagtga ttctgagtat gataaaatca tgattaatga acaagcttct gaagaatatt
    10621 taagttatct aaaaaatata aaagtgtatg ttattaatac atacacagga gtattttata
    10681 caaatacgtc atatgctagt ttatatgatt ttaaacaaaa aactaagagc tattgtaatg
    10741 tagagataat aaataagata ggaaagagct catatattaa aacaataaat ggagaaaaat
    10801 ttgaactgaa taatctgagt ctggaactaa atgaagtaga tgaaggtttt gaggcatatg
    10861 tatcttttcc agaagagcca actatagaag atggaatagt atatactaat tttcaaatat
    10921 ttaaacaagc tacagaaaaa gtaagattat tttttgtagc tagtttaagt ttagcaatta
    10981 tatgtttatt atctataatt ttatatatca aaataaaagg tgaagtttta aaaagaaata
    11041 atgtattttt actaatatac agtaagatac ctatggaatt taatgtaata ttagtatcta
    11101 tttcaattgc aattttaact atatatgctc ttgctgtatc ttatcatatt gatgtaattg
    11161 cattagtttc tttatcttta ctgatagtat caaataatat attttttata aatgtgcaat
    11221 tgagctattt agaaaataaa atgtgtatat ttaagacaag tattatagta agagtgattt
    11281 tatggttaat aaaaactgta agggaggtca gtaacgctat aaagaaagta tctttagcaa
    11341 ggaaagttat tgttatagtg ataatatctt tagctttaat catggcaatt agcactcgaa
    11401 gtataggtat gggattactg ttttctatat gtattttttt aggatttaca atatatataa
    11461 ctaaaagact ttcatatctt agttacgtaa tagaaggtac agaaagaata aaaaagggag
    11521 aattagatta taagataaaa attactggga atgataattt tacgtcttta gctgaaaata
    11581 taaataatat tggagaaggt cttgatagag ctatagaaga gcaagtaaaa agtgaaagaa
    11641 tgaagtctga ccttataaca aatgtatctc atgatttgaa aactccactt acttctataa
    11701 taaattatgt agatttaatt aaaaaagaag aatcaataca accagagtat ataaatgatt
    11761 atataaatgt acttgagtca aagtcaaaaa gactaaaatt attgatagaa gatttatttg
    11821 aagcgagtag agtaagtagt ggcaatatag aattacaaat tagcaagatt gatttagtgc
    11881 aactattaag acaaagtata ggtgaacttg aagaaaaatt atctaaaaat aatttatatt
    11941 taaaattaaa tgttccaaat gataaggtgt atatatgggc agatggaaga agaatgtata
    12001 gagtatttga aaatctttta tctaatatag caaaatattc cttagaagaa actagagtct
    12061 atattgatgt atatgactat ggtgaaaatg taaaggtaac tatgaaaaat atatcttctt
    12121 atgaattaaa ttttgaccca agtgagatta tggaaagatt taaaagagct gatgaatcaa
    12181 ggaatactga aggaagtgga ttagggcttg ctattgcaag agatttagta gctttacaag
    12241 gtggaaaatt ttatatagaa atagatggag atttatttaa agcaaattta gagtttcaaa
    12301 aatatgaaga agaaataaca aatatggaat gagatagtat ttaagtatat atattttttt
    12361 tactgtcgaa agcttttatt ataatatatt agaatattta cagtagagaa tgaagagtaa
    12421 aaacagagta actttaagtc actctgtttt ttatttaaaa tcaataatat aacaacttaa
    12481 attaaaattg tacacatagt tttaaaataa cttatacaat aaaacattat ccaaatatca
    12541 caagataatt ccaaataaat atatagatat cactcctgta ataatagaaa taccaataga
    12601 tttaaactta tatgcaacaa gaagtacaat cataaaagat ataattttag ggttagctat
    12661 agataaatat agactatctc cattaaaaaa tacatcttta gcagttaagg aagtaagtat
    12721 tgctacaggt ataaatttca tgattttttt caaaaaatca ggcatctctt tttttgaaaa
    12781 aattaacata ggaagcactc ttggtagata tgtaacaatg tacattccaa ttataataaa
    12841 aaatatataa ttattattca taagattcct cctttttaca gtaagattct tctataaaga
    12901 aaccaattaa agatgctaaa attgatgcaa ctattattac taaattgctt ttgaataatg
    12961 catataaaat aacagaaata atgattgatg atataaatac tacaatataa atcttatttt
    13021 ttatttgaga aactattaaa gctataaaca tagaagtcaa tatgaagcca gaaatagaac
    13081 tgtctataga tatactttct cctaaaaatg ctccaataaa attagctaaa actgatgaaa
    13141 ttaagcagaa gaaattaaga taaatagcat ttctatcaga ccaatttcca gcagtaaatt
    13201 tttcataatt aactgcaaaa gtttcatctg ttatagtatg acaaaatggc aatataaatt
    13261 ttggactttt attttttatg tacatgttca aattagaact cattagaaaa tgtcttaagt
    13321 taactataaa tgtagtcaaa acaatagatg ttacacttgc accagtagaa atcattgaag
    13381 ctgcaatgaa ttgagaactt cctccaaata ctaaagttac cattagtgct atttgaaaag
    13441 gtgaaagacc agatttttgt aatagtattc ctcctactat acctataggt atataaccta
    13501 agaatatagg aattgaagca ataaagcttt cttttaattg ttgagttctt tccacaataa
    13561 atcactcctt ttgtattaaa tgtattaaag tattagtaaa acagaaaaat agattaattg
    13621 tataattgca attataatta aaaataaatt tggattaata tataaaatac tatacaacaa
    13681 atagataatc ttaaacggtt attaaatttt atctatttgt tattatgatg taataataca
    13741 tattaatctc tataagttaa ttactatctg gtgtaatttt attttaacaa caaaaaaaaa
    13801 tacacacaat taaaatattg tgtgcaatac aattattttt tctcttctaa tagtcttttt
    13861 aatacgctca aaccagcttt aagttcttct gtactttctg tagcacatac agctattctt
    13921 attgcagaaa ttggtttttc ttttccaaca gcaaaacgtt cagaagcata gacttgtaca
    13981 ccttctttaa gtgcttgtat ctcaaatttt tctgccatta ttccatcagg tagaatcaac
    14041 catctaaata tacattcttc atttcccaaa agattatatc cagataaata ttgattaata
    14101 atcttgtttc ttcttcttgc agatttacgg cgtgcattaa ttaatttatc ggcttcacct
    14161 gatgtaatca tgcgataagc aatttctgtt aaaaaataag attgagatag attaatgttg
    14221 tataatgcgc ttgataatgc ctctcgatac tgtttaggtg tagagatata tgctagccgt
    14281 aaactaggtg caataatttt tgataaactc gtaatataaa ttgtttgatt tggcagatag
    14341 gaagccactg gatttaaatg tgtttcatta agtaaactat gaatagcatc ctcaataaca
    14401 attaaattgt atttagatgc aatatttgca atcatttttc gtccattttg tgacattata
    14461 tgtgtagttg gattttgata atctggtatt atgtatagac ctttaatatt ttcattttta
    14521 caagcatata atagtccttc ttcactaatc tcattatctt cttgtttaat tggaattagt
    14581 tgaatcccaa gcattttagc tgctgtcttt attccaggat aagttaatgg gtctacacct
    14641 attctatctc catgttgaaa caaaccagct aaaatagcaa caattgcatt ttgtccacca
    14701 cttgcaggaa gtaagctatc tgatgtagtt tcaagcccag ctttataaat taatttggca
    14761 atagcttctt tttgccattt agcaccatct ctttgtccat attggaatat agttttaaaa
    14821 tctatttcct taattatgtg tttaaacaaa gtattcattt cttctagcgt gaaatctgga
    14881 ttcattgtgc ccatttcaat aaatgtaatt ttattattac tggacatcaa gaatagattt
    14941 gaacgtgtat cataagatac aaaagttcca cttcctgtaa ctccacttat tagacctttt
    15001 ttttcacaaa ttttaaaagc tctagagata gtactcacat taacatctaa gaaatctgcc
    15061 aattcacgtt ggggtggtaa tttagtacct ggtaataaaa atccattgtt gatatcttgt
    15121 tctagttgtt ctacaagcgc cttatataat atttgccctt ttgaaggtct ctttggtttc
    15181 cagttcatag gataattttc aaaagaatta attggcataa gttttcacct cacattatta
    15241 atttgatttt ttctttatct aaaacaataa attctaaaga tacaaataaa aactgatagg
    15301 aaataattct atcagttttt gtcttttaat tgatttcaaa tcttcctata atttttatac
    15361 cttctttatc ataaagaggg attgtttttt taaatatatt aaaatttctt tttcttgtat
    15421 ataaaacagc ttcttctggt gtctttggtt ggttatcaca atcgtacaaa tttctttttt
    15481 ttaactaaaa gcaataatac ataaaattat tattgctaat gatactctta atgtggtata
    15541 tagtcatagt gtcacatgtc tatcaatagt tttttcagta attattgtaa cgaatagtag
    15601 gactcataaa atacttagaa atatgttttt agataaattt taaatatata atctaactta
    15661 tatctataaa ttaacactat tattctccaa ttccatttct agttttttta taaatttatt
    15721 aaattcttct ggttgccttt ttccaaacaa tactcttaca agagctgaat tgatttttcc
    15781 aaatatattc ctcttgctct cactttcaat aaaaataagt tttgtatttt ctaagtcaat
    15841 atgtactaat tcatatctag taatagtact ttctctttta ttgcttgttt ttatctcata
    15901 tactctattt ttttcgaaat tagttatttc aaccttaaat cttttattat ttttttgctg
    15961 tacaaatgtt cctactgctt ttttctcatt aaaattagga aaatttagtc ttgcagattt
    16021 tgtaaatata ttaaatatgt cttttgcaga atattttaat aaaacttcag t
//
LOCUS       DAEPHU010000086        16040 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 01A10CD0081
            SAMN05941466-rid12468953.denovo.086, whole genome shotgun sequence.
ACCESSION   DAEPHU010000086 DAEPHU010000000
VERSION     DAEPHU010000086.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941466
            Sequence Read Archive: SRR6291087
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 16040)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16040)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068158.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 22:43:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,892
            CDSs (total)                      :: 3,805
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 87
            rRNAs                             :: 8, 1, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 55
            CDSs (without protein)            :: 55
            Pseudo Genes (ambiguous residues) :: 0 of 55
            Pseudo Genes (frameshifted)       :: 21 of 55
            Pseudo Genes (incomplete)         :: 28 of 55
            Pseudo Genes (internal stop)      :: 16 of 55
            Pseudo Genes (multiple problems)  :: 8 of 55
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16040
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941466-rid12468953.denovo.086"
                     /strain="01A10CD0081"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            complement(281..568)
                     /locus_tag="KR231_003144"
     CDS             complement(281..568)
                     /locus_tag="KR231_003144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0005497.1"
                     /translation="MRLNVTKQNTIEVENSRKEDVYFVIVDNVFFERQGDVFNSITNN
                     NLNNYDVKILPTDNVFLELKITSTKDLEPVFIVVEDRQYNHGSIMFKPVLV"
     gene            complement(588..863)
                     /locus_tag="KR231_003145"
     CDS             complement(588..863)
                     /locus_tag="KR231_003145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0005498.1"
                     /translation="MSLFVGGWSKFRAVEEEDLKVFNEAVGMLEGVGYEPLIVSTQVV
                     AGTNFKFICNATSVTNPPQNYLAEIVVFKPLPCDEHNATITSINIIK"
     gene            complement(1500..1679)
                     /locus_tag="KR231_003146"
     CDS             complement(1500..1679)
                     /locus_tag="KR231_003146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0005499.1"
                     /translation="MGKDRFEKVYSQGKINATEIWVDKETGVNYVFHYYGHAAGFTPL
                     LDREGKPVISPIVSK"
     gene            complement(1964..3439)
                     /locus_tag="KR231_003147"
     CDS             complement(1964..3439)
                     /locus_tag="KR231_003147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBH0005500.1"
                     /translation="MKRKPQYLIIFEHIIQQIYTGKITIGDRLDSIKSMSEEYMVSKN
                     TIKTVIKMLSEKGFIETKAGSRPVLIQSTSKQSIESDLLYEKILQISEIYKIFSLIFP
                     SIAMYNIKRFTSKDFEELNEIIDCMEKNSSNYLVFKEQRLKYINKLISKTNNFLIHHF
                     CEIIQHDVIISQLAYNFDNLDNLDNCCIDFFRNKYIEQVRKTYLYGLDGNLIEFKKLL
                     TYMYKACRESILKMVENRAPQSIDTSSFNSVTLEKCYLYDLIVSDVICQIFEGNIKIG
                     DCLPSITSIINRYNVSLPTVRSAYNELNELGIAKTINGKGTYITLFSEYDDDYINTEE
                     GAKRLSLLLDAMEFVTITLEDVVLLLGNKMDLIAVDKIETHLRYLQNNCEECKVYPDF
                     VLLCKIVDYTQIYVLQETFLHLKQYMIFGIYLERFFHEEYNEILKTRFDVCFEILRYL
                     KKGDVERFAESFSNIFKESLQYLKKVISSLNVDMRVKLDIL"
     gene            4508..5686
                     /locus_tag="KR231_003148"
     CDS             4508..5686
                     /locus_tag="KR231_003148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GGDEF domain-containing protein"
                     /protein_id="HBH0005501.1"
                     /translation="MKYHIFLIITTILIIELCNIYICKIASFRNKNITIHKNYKYIFL
                     IKPLTFLIIIFTKLPLPLYYILFYIVSHKLLLSRKSSTNNHFIPNMAVISFCILHLIT
                     VSTISLVKNTSPDIIFANMTYKLISILIASILDFILWYSMNKIKEHIYIITQNQIEFS
                     LFLKFIWFTLGYILFDSIQITFAPPSSLTSYFILGSNILLILQLIIFINHIYSIEKNI
                     YLEKEHNRLKMIKQEQLLKVNLLKKKANIDELTSAYNRKFAFEKIQHYIDNNLLFSLI
                     YIDLDKLKTINDTYGHLAGDNYIINFSSIVIENLGIDDIFARIGGDEFIVIMPKSNEN
                     TTKEFIEKISKIMDNTISFSYGIVEVSSENKMTVEEIINIADIRMYTNKQNNHKRNNN
                     "
     gene            6036..6917
                     /locus_tag="KR231_003149"
     CDS             6036..6917
                     /locus_tag="KR231_003149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GGDEF domain-containing protein"
                     /protein_id="HBH0005502.1"
                     /translation="MPAYLFDSNSIANIYRVFPISFSFIVTGLYFSYKNNKNNKINFE
                     AVLEDKKNLIFLLSLMFGMYLYLCLSLSIYYTVGNVLILKLYGIKSAIIVLVGNYIAE
                     RYSFRITQIKGYDIKNQIEYVESVKTEYEINKLNDIVYTDLLTGFYNRPFVNQKLSEW
                     TSNHYKFTLCFTDLNSLKPVNDKFGHQFGDKYISTTAQIIKKLINVENSLLFRYGGDE
                     FLFLLQNTSCVEAEKIMININYELSKISNTDEYPYALSISYGLVEWDGISDIETLISK
                     ADSLMYENKLKNKSTLN"
     gene            7108..7275
                     /locus_tag="KR231_003150"
                     /pseudo
     CDS             7108..7275
                     /locus_tag="KR231_003150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418025.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="EAL domain-containing protein"
     gene            complement(7535..10102)
                     /locus_tag="KR231_003151"
     CDS             complement(7535..10102)
                     /locus_tag="KR231_003151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002602373.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate, phosphate dikinase"
                     /protein_id="HBH0005503.1"
                     /translation="MIYYVLPLEHKQATIEIVGGKGMSLSKLLTAGIPVPDGFHVTTA
                     SYQIFVETNHIQSRINKLLDGIDSNNTSQLEDVSKKIGELFHNGEMPQEVSDAIKMAY
                     AGLGNISVAVRSSATAEDLPDASFAGQQETYLNIQGEDKVIDSVKRCWASLWTARAIA
                     YRVKNNIKHEIVALAVVVQKLAFSDSSGIMFTLNPINGRRSEMIINAAWGLGEAVVSS
                     LVTPDTIVVDKDSERIISYEVANKEIMTVRTSEGTEETMVPERLRKKYALTRNQVMQL
                     IQLGKKIEKYYQMPMDVEWALEKDKLYIVQARPITVLPPEWVLPEQDVVYTKGSLAEH
                     LPNPVTPLFATLGLEIVNRASELLWIDMFGKSAKKLLPKNGAYTVINGYVYLSAKSNP
                     LLIAIKSLSPRSLRRTLMNSVARWETARKGYEDAIKQWEEKPLHTMNAHQIMEGIQTI
                     FYAACIYFTRIQLTLPAASISETLFTKLFQGAVRRAGITDTSVFLLGFDTIVLQSEKE
                     LWGISEWVKQNNSINLYLQNSPAIKIAEDFMSSVVPVGVSQEVWIEWKNRINKYFKEF
                     GRTAYEFDFAHSTPQETLTPTFESVKTFVEGKGESPFLRQTTFEKRRKHAEEEILQHI
                     GGLRKKLFFKLLHWAQETSPMRENAIYLMGMGHPLIRCMFQEISERFIRGGAISHLDD
                     IYWLTKSELEVLIEQLDKNKSLSDMNGIIPVRKAELKKYMGYVSPSKLPEKNKKTISQ
                     AQQKQKDGKIVLTGIGTSTGVVTAPACVLNSPADFESFQPGSVLVAVTTTPAWTPLFS
                     SASAIVTDIGGPLSHSSIVAREYGIPAVMATHIATRAIKSGQMITVDGLAGTVTFDE"
     gene            complement(10105..10710)
                     /locus_tag="KR231_003152"
     CDS             complement(10105..10710)
                     /locus_tag="KR231_003152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002591427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBH0005504.1"
                     /translation="MPKGIVLTPEQQAERREKIVAVALSLMAENGFQKTSMREIAVLA
                     NMGKSSLYDFFKTKDEIVVYAVEKEIEKTIQQVHRIIDGEPSPQQCLRKIMLNHLRFP
                     EQYRTVLMWLNTESDYLEEEYRKRLKDARYAYQDIIKSVIDNGVTTGIFRKTDTALVT
                     RLLINSMLSISYTSRPLDSSEKMLDETMNIFLHGIMNDGGE"
     gene            complement(11084..12544)
                     /locus_tag="KR231_003153"
     CDS             complement(11084..12544)
                     /locus_tag="KR231_003153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent glyceraldehyde-3-phosphate
                     dehydrogenase"
                     /protein_id="HBH0005505.1"
                     /translation="MFNELKTKENVYKNLINGKWVESNSRKPIEIYSPIDNSLVGKVQ
                     SMTKHEVDEVIKNTKESIKVWAEMPVYKRANIFHKAADLLLENIDEIANILVLEIAKD
                     IKSARAEVERTADFLRYTADVGKNMEGEAISGDNFPGGTRNKMSYVSRVPLGTVLAIS
                     PFNYPVNLSMSKIAPALIGGNAVVLKPATQGAISALHVVEIMRKAGIPDGVLNTITGR
                     GSEIGDYVVTHKGINFINFTGSTEVGQHISKISGMVPLLLELGGKDAAIVLEDADLDF
                     AAKNIVSGAYSYSGQRCTAVKRILVQESVADKLVGKIKPLVEKLTIGNPMDEVVITPL
                     IDNKATDFVQGLVDDALHKGAKLITGNVRKNNLFYPTLLDNVNVDMKIAWEEPFGPVL
                     PIIRVKDINQAIEIANQSEYGLQSSVFTSDIDKAFYIADKLEVGTVQINNKTERGPDH
                     FPFLGVKASGMGTQGVKYSIEAMTRPKAVVVNVREL"
     gene            12898..13476
                     /locus_tag="KR231_003154"
     CDS             12898..13476
                     /locus_tag="KR231_003154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBH0005506.1"
                     /translation="MAKSFTEIEKDNIRKRLISECEINWSKYGYKKTNIDELCSKSGI
                     AKGSFYTFFDSKEKLFFEVLNGIQNRLISSVDEILSNMPPKEGFAKALKMLYRLYDKN
                     PFLYSPNNTDYITLLNKIPKEMLSQLEYSNVQSFYSLIERHNLKLKIEKEKAFGVCNA
                     LLSSLLLKEDIGYDYIEVFDFMVDNLVEHILE"
     gene            13527..13760
                     /locus_tag="KR231_003155"
     CDS             13527..13760
                     /locus_tag="KR231_003155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902005.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0005507.1"
                     /translation="MIELIQRLNDIIYKINDKLNIHTKLVDPSSELMPLYSMLSIIVS
                     IFLIILGIKVRKKFLIIIAIISIIINILIILDR"
     gene            13769..15019
                     /locus_tag="KR231_003156"
     CDS             13769..15019
                     /locus_tag="KR231_003156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBH0005508.1"
                     /translation="MVKSSNTFNKNFNLMILGQIISLFGASILKFALSLYILDITGKA
                     EIFATILAVSSIPIIVFSPIGGAIADIFNRRNLMVIFDFSSSLTVLILAVFLFNNNGS
                     ILLVGIIMTILSVISTMYQPTVQSSTPLLVDNEHLMNANGIVAGVASLTNIAGPVLGG
                     VLYGVIGINAIIVISCVSFFLSAIMEIFIQIPFIKQEQNSNIIKTIFTDIKDGIVHIC
                     KENRFILKILFLAIAINLFLSSMLIVGIPYIVKITMGASNFLYGLAEGAISFSSLVAA
                     VSIGIFSKHLKITNLHISFIICAVMFIPMAVSVYPFILNTGFPVPFLIFIVSSMLIFF
                     TTTLISIYVITVTQLKTPNELLGKVMSILFAGTAIAMPLGQVMYGKLFDLLSDRVYII
                     ILGVGFITLLIAFVSKITLRNENL"
     gene            15180..15749
                     /locus_tag="KR231_003157"
     CDS             15180..15749
                     /locus_tag="KR231_003157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrolase"
                     /protein_id="HBH0005509.1"
                     /translation="MSYMPTLEQAWEILRKYNKEEFHIRHAQIVSGVMRYYAKEYDPE
                     RVEFWEIVGLLHDLDFEMYPDEHCVKQRELMTELDLDKSIIDSTISHGYGLTGSDVKP
                     EQFMEKVLFAVDELTGLIGAAAIMRPSKSVSDLELKSVKKKFKDKSFAAGCSRDVIRS
                     GAEMLGWELDKLIQTTIEAMRSLIPEMAI"
BASE COUNT         5582 a         2599 c         2074 g         5785 t
ORIGIN      
        1 aaatagttca actatactgg tttaaatagg ttatctttat ttgcttaaat agttcaacta
       61 tactggttta aataggttat ctttatttgc ttaaatagtt caactatact ggtttaaata
      121 ggttatcttt atttgcttaa ataagttcaa ctatactggt ttaaataggt tatctttatt
      181 tgcttaaatt agttcaacta tactggttta aatagttttc ctttagttta aataattcac
      241 ctatacctac ttgaatagtt cacttttatt tgcttaaatt ctataccaat actggcttaa
      301 acattatact accatgattg tattgtctat cttcaactac aataaaaaca ggttctaaat
      361 ctttagtaga tgttattttt aattctaaaa aaacattatc agttggtaat atttttacat
      421 cataattatt taaattatta ttcgtgatac tattaaatac atcaccttga cgttcaaaaa
      481 aaacattatc aactattaca aaataaacat cttcttttct actattttca acctctatag
      541 tattttgttt agttacattt agtctcatct tccacctcct attaatatta cttaattata
      601 ttaatacttg taattgttgc attatgttca tcacaaggaa gaggtttaaa aacaactatc
      661 tctgctaaat aattctgtgg aggatttgta actgaagtag cattacaaat aaatttaaaa
      721 tttgttcctg ctacaacttg agtagaaaca ataagtggtt cataaccaac cccttctaac
      781 attcctacag cttcattaaa tacttttaaa tcttcttctt cgacagctct gaattttgac
      841 catccaccaa caaaaagact catataaaaa cctcctttat atatatattt atttatatat
      901 atagtagtac caattttctc aatattcaat attttctgtg taactggtca atgaaaatgc
      961 ataactggat aaaaatactt ataaaataac ttaactttac atataaatag cttaatttac
     1021 atgtaataag attattctac aatatgaaat acatcttatt ttgaatatat tctaaataca
     1081 ataatggata ttttcaatta ttatacttag aaaatatcca ttacttaatt tgttttattt
     1141 aaaatcacat agagacttta ttattttttt tattgcatga atagctattt caggtatcat
     1201 aaggtgatat accccctcct tgaaaccaca aaaaacataa caaactttac gaatcttgtc
     1261 ttaaaagacc acaggtacat tccttatttg tggattggag tagccataac aagcaaattt
     1321 tacaattttt atgatgacaa aaatcaataa aatcgcttag tatataacac gaaatactac
     1381 ttgttgctat taagaatagt tagataggaa gtatgcatta taccaataaa ggaatcaata
     1441 aagaaagtta aaacatccct acaaattaaa aatctgttac atttttctat atttaaacgt
     1501 tatttactta caattggaga aataacaggt tttccttctc ggtcaagtaa aggcgtaaat
     1561 ccggctgcat ggccataata gtggaataca tagttcacac ctgtttcttt atccacccaa
     1621 atctccgttg catttatttt tccttgtgaa tatacttttt caaatctatc ttttcccatt
     1681 ttataatcct ccatattttt gattggtcta tgccttcttc acttaagtag aaaaaataca
     1741 taacttattt ttttaattct aatatgagca cgtaaaaatg tcaaacagct tatttaattt
     1801 cataacttca tgttactgtt cgtaaccttg tctgtttact tacactgcat tacagcacca
     1861 ttttatcctt tacattattg tattgcacac agtaaaaatg cttactttat tggatttttc
     1921 aactaaaaaa aggatttttt ctccacagaa catttactat tttttataat atatctaatt
     1981 ttactctcat atcaacattt aatgaagata taaccttttt caaatattgt aaagactcct
     2041 taaaaatatt agaaaaagat tctgcaaatc tctcaacatc tccttttttt aaatacctaa
     2101 gtatctcaaa acatacatca aaacgtgttt tcaaaatttc attatattct tcatgaaaaa
     2161 atctctctaa atagattcca aatatcatat attgttttaa atgtaaaaat gtttcctgta
     2221 atacataaat ttgtgtataa tctactatct tacaaagtaa aacaaaatct ggataaacct
     2281 tacactcttc acaattattt tgtaagtacc ttaaatgagt ttctatttta tctacagcta
     2341 tcaaatccat tttatttcct agtaaaagta ctacatcctc aagagtaatc gtaacaaact
     2401 ccatagcatc caaaagcaaa ctcaaccttt tagctccttc ttctgtattt atataatcat
     2461 catcatattc agaaaaaagt gttatatatg ttcccttgcc attaattgtt ttagcaattc
     2521 ccaattcatt tagctcatta taggcacttc taactgttgg aagagataca ttatatctat
     2581 taattatcga agtaattgat ggtagacaat ctcctatttt aatattgcct tcaaaaattt
     2641 gacaaattac atctgaaaca attaagtcat ataaataaca tttttccaac gttacagaat
     2701 taaaactact tgtatctata ctttgtggag cacgattttc taccatttta agtatggatt
     2761 ctctacaagc tttatacata tatgttaata gttttttaaa ttcaattaga ttcccgtcca
     2821 atccatataa gtaagttttt cttacctgct ctatgtattt attacgaaaa aagtctatac
     2881 aacaattatc caagttatcc aagttatcga aattataggc caattgtgaa ataatgacat
     2941 catgctgaat aatctcacaa aaatggtgaa tcaggaaatt atttgtttta cttattagtt
     3001 tatttatata ttttagcctt tgttctttaa agactaaata attagaacta tttttttcca
     3061 tacaatcgat aatctcgttt aattcttcaa agtctttaga tgtaaatctt ttaatattgt
     3121 acatagcaat agaaggaaat attaaactaa aaatcttata tatttctgat atttgtaaaa
     3181 tcttctcata taataagtca gattctattg attgtttact cgtactctgg attaaaactg
     3241 gtctagaacc agcttttgtc tctataaagc ccttttctga gagcattttt attacagttt
     3301 ttatagtatt ttttgatacc atatattctt ctgacatgct ttttatagaa tcaagcctat
     3361 ctccaatagt aattttacca gtataaattt gttgaattat atgctcaaaa ataattaaat
     3421 attgtggttt tctcttcata tttttcctct tcgataaatt agatttattg ttttttgtaa
     3481 ggtatattta cttttattta atagggcaaa atagttgctt attttttcct cataatctat
     3541 aattaatata gaccatttat atatatggtc taagttttat aatactgtaa tgcagtaaaa
     3601 tagcatattg tagctatact acagcaaatt aacataccat tgtagtatat taattggaat
     3661 aattttaagt acttcaaaat tccagcaaaa catatatgtg tttttgatat tatgtatatt
     3721 cgttaataga atagctatac ttgttttaca taataaatta tatgatactt gctatatgta
     3781 attactatat ttaatacaca taactattat acttactata tgtaattact atatttgata
     3841 cacataatta ttatacttac tatatataat tactatactt ggacacataa ctattatact
     3901 tgctatatgt aattactata ctttatacac atagttatta tacatgctat atataattac
     3961 tacacttgga cacataacta ctatatttac tatatgtaat tatactatac gtggacatat
     4021 agttatcata catactatat gtaattacta tacttggaca cataactatt atatttgcta
     4081 tgtgtaatta tactatactt ggacatatag ttatcataca tactatataa ttactatact
     4141 tggacacatt atcatacata ctatatgtaa ttactatact tatacacata gttatcatat
     4201 atactatata taattactat acttggacac atagtcatca tacatgctat atgtaattac
     4261 tatacttata cacataacta ttatactttc catacataat tactatattt ggacacatag
     4321 ttatcataca tactgtatat taagatataa tactttttaa attttatata acacagacac
     4381 atgcaataaa aaagaaggta tccataataa gctctttgca tgtacctaaa taaaaactgt
     4441 aaaatagaat atataaaatc taatctattt taagtaaata caatttcact ttaaaagagg
     4501 atgtactatg aaataccata tatttttaat cataactact atattaataa tcgaactatg
     4561 taacatttac atatgcaaaa tagcatcttt tagaaacaaa aatataacta tacataagaa
     4621 ttacaaatat atttttttaa taaaaccatt aaccttcttg ataataatat tcacaaaatt
     4681 accattacca ctatattata tattgtttta catagtaagt cataaattgc tcttaagcag
     4741 aaaaagttct actaacaacc attttattcc caatatggca gtaataagtt tttgtatttt
     4801 acaccttatt actgtaagta caatatcact tgttaaaaat acaagtccag atataatatt
     4861 tgcaaatatg acctataagt taattagtat tttaatagct tctattttag attttatctt
     4921 atggtactct atgaataaaa taaaagagca tatttatata ataactcaaa atcaaataga
     4981 gttcagtcta tttttaaaat ttatctggtt cactttagga tatatattat ttgatagtat
     5041 acaaattaca tttgctccac caagttctct aacttcctac tttatattgg gaagtaacat
     5101 attattaatc ttacaactaa ttatattcat caatcatata tattccattg aaaaaaatat
     5161 ttatttggaa aaagaacata atagactaaa aatgataaaa caagaacaat tactaaaagt
     5221 aaatttatta aagaaaaaag ccaacattga tgaattaaca tcagcatata atcgaaaatt
     5281 tgcttttgaa aaaatacagc attacattga taacaattta ttattttcat tgatatatat
     5341 cgatttggat aaattaaaga cgataaatga tacatatgga catttagctg gggataacta
     5401 tattattaac ttctcaagta tagttattga aaacttagga atagatgaca tatttgctag
     5461 aataggagga gatgagttta tagttattat gcctaaatct aatgaaaaca ccacaaaaga
     5521 atttatagag aaaataagta aaattatgga taatacgata tcttttagct atggtattgt
     5581 agaagtttct agcgaaaaca aaatgactgt agaagaaatt attaatattg ctgatattag
     5641 aatgtacact aataaacaaa ataatcataa aaggaacaat aactaaaatg aatatttaca
     5701 tgagcttact tgtagtctca ctatgttttt tatcttatta tctctatcat tataattttt
     5761 ttaaatatct ggacataatg attaataact ctaaaaataa atacacagta tatattatat
     5821 attctatatt taattattta atttttatta tttgtactta tttaaagttt catctaatta
     5881 taaattggac aatttttatg ttgattttat tcatacaaat taaagtaact tataaaatct
     5941 ccacaataaa aaacattttt tattcactaa actgctccat cattggttta gcaataaata
     6001 tattttttag gtctttaatg tcaatagtgt taaatatgcc agcatattta tttgatagta
     6061 attctattgc aaatatttac agagtatttc ctatatcatt tagctttata gttacaggac
     6121 tatatttcag ttataaaaat aataaaaata ataagattaa ctttgaggca gttttagagg
     6181 acaaaaaaaa cttaattttc ttattgagcc ttatgtttgg aatgtacttg tatctatgtt
     6241 tgagtttgtc aatatactat actgttggaa atgtattgat tttaaaatta tatggaatca
     6301 agtctgccat aatagttttg gtaggtaact atattgcaga aagatatagc tttagaatta
     6361 ctcaaataaa aggttatgat attaaaaatc aaatagaata tgtagaaagt gtaaagacag
     6421 agtatgagat taataaattg aatgatattg tatatacaga tttactgaca ggtttctaca
     6481 atagaccttt tgtgaatcaa aaactatcag aatggacatc aaatcactac aaatttacct
     6541 tatgttttac tgatttaaat agcttaaaac ctgtaaatga taaatttgga caccaatttg
     6601 gtgataaata catatccact actgctcaaa taataaaaaa acttataaat gtagaaaatt
     6661 ccttactatt tagatatggt ggagatgaat ttttattcct tttacagaat acaagttgtg
     6721 tagaagcaga aaagataatg attaatataa attatgaatt atcaaaaata agtaataccg
     6781 acgagtatcc ttatgctctt tccataagct atggattagt tgagtgggat ggaatatccg
     6841 atattgaaac tttaatatca aaggcagatt ctttgatgta tgaaaataag cttaaaaata
     6901 aatctacttt aaactagcta gttcagatat tctacaaaat atatattata agatagtact
     6961 aagaatgtca aaatatatag attttgcaaa tattgaatac agtttactaa tgaatgcact
     7021 ggatgtaagt gttagtaaac acctattaga tgaacacttt actgttgttt gggctaatga
     7081 ccgttattat gaaatgttcg gctataccta gctaaaaagt taaaaatgac cactgtagcc
     7141 gagggaatag agactagttt tcaaaaagat ttcttgcaag aaatagactg tgatatgtta
     7201 caaggatacg tgttctctag acctttacca ataaaagact ttgaaaaact tatgtttcaa
     7261 aactcctcca attaacaata taaaattgct tattataagt gatattattg tatcaacaaa
     7321 taaaggaatt gtctcaaaat tgattttttc taatcaaatt tttattttga gacattctca
     7381 tttttttgca taagaaaata cccaccaagc tacggttttt cttaccgctg ttcggtgggt
     7441 attagtagta ttatgaaatc tgaaaacttt aagtattact acttccgcta gcgcaatcac
     7501 aaaggtcgaa agcttcaaag cgaaaatagg ctttttactc atcaaacgtc accgtacctg
     7561 ccaacccgtc caccgttatc atttgtccgc tcttaatagc tcgtgtggca atgtgtgtag
     7621 ccataacggc tgggatgcca tattcacgtg cgacaatgct tgaatggcta agaggaccac
     7681 caatgtccgt tacaatcgca cttgcagatg aaaataatgg tgtccatgct ggagttgtgg
     7741 taactgcaac caaaacactt ccaggttgaa agctttcaaa atctgctgga ctattcagta
     7801 cacaagctgg agccgtcaca acaccagtac tggtaccaat gcccgtcaac acaattttcc
     7861 catctttctg cttctgttgt gcttgtgata tagttttttt gtttttctct ggcaacttgg
     7921 atggtgacac ataacccatg tattttttaa gttcagcttt tcgaacaggt attatcccgt
     7981 tcatatcaga tagagacttg tttttatcca actgctctat aagtacctcc aattccgatt
     8041 ttgtgagcca ataaatatca tctaaatgtg aaatagctcc tcctcgtatg aatcgttctg
     8101 agatttcctg aaacatacaa cgaatcagag gatgtcccat tcccatcaaa taaatagcat
     8161 tttcacgcat aggagaggtt tcctgtgccc aatggagcaa cttaaaaaat agttttttac
     8221 gcaatccacc tatgtgttgt aaaatctctt cttctgcatg ttttctacgc ttttcaaacg
     8281 tggtctggcg taaaaaagga ctttcccctt ttccttccac aaatgttttt acggattcaa
     8341 aagttggtgt aagtgtttcc tgcggtgtgg aatgcgcaaa atcaaactca taagcggtac
     8401 gaccaaactc tttaaagtac ttattgattc gatttttcca ttctatccat acttcctgtg
     8461 aaactccaac aggcacaact gaagacatga aatcttctgc tatctttatt gcaggactgt
     8521 tttgcagata aaggttgatg ctgttatttt gctttaccca ttctgaaata ccccacaact
     8581 ccttttccga ttgcagaaca atcgtatcaa acccaagcag gaaaacggaa gtatccgtta
     8641 taccagcacg tcgaactgct ccttgaaata attttgtaaa taatgtttca ctgatagaag
     8701 cagcaggcaa tgtaagctga atccttgtga aataaataca tgcggcataa aatattgtct
     8761 gaataccctc cataatttga tgggcgttca tagtatgcag gggcttttct tcccattgtt
     8821 taatagcatc ctcatatcct tttcgtgccg tttcccagcg tgcaacgctg ttcataagtg
     8881 tcctacgtaa agagcgtggg gaaagggatt tgatagcaat caaaagtgga tttgatttag
     8941 cagaaagata aacatatcca ttaataaccg tatatgcccc gttttttggt aataattttt
     9001 tcgcactttt accaaacata tctatccata aaagctctga tgcacggttt acgatttcaa
     9061 gaccaagcgt ggcgaacaaa ggtgtaacag gatttggcaa atgttctgcc aaacttccct
     9121 ttgtgtatac aacatcctgt tctggcaata cccattctgg tggcagaaca gtaattggac
     9181 gagcctgaac aatgtacaat ttatcttttt ccagtgccca ctctacatcc ataggcattt
     9241 gataatactt ctcaattttc tttccaagct gtatcagttg cattacctga ttacgagtaa
     9301 gagcatattt ttttctcaac ctttcaggaa ccatggtttc ttctgttcct tctgaagtac
     9361 gaaccgtcat aatctcttta tttgccactt catacgatat aattcgttcg gagtccttat
     9421 ccactacgat tgtatcgggt gtaactaagc tagaaaccac cgcttcacca agcccccatg
     9481 cagcgttaat aatcatttcg ctacgtctac cattgattgg gtttaacgta aacataatac
     9541 cagatgaatc ggaaaatgca agcttttgta ctacaacagc aagtgcgaca atctcgtgct
     9601 ttatattatt cttcacacga taagcaatag cacgagctgt ccataaggaa gcccagcatc
     9661 tctttacaga gtcaataact ttatcttcac cttgtatgtt aagataagtt tcctgctgac
     9721 ctgcaaaaga agcgtcaggt aaatcttcag cagtcgcaga cgaacggaca gccaccgata
     9781 tgttccctaa tccagcataa gccattttaa ttgcgtccga cacttcctgt ggcatttctc
     9841 cattatggaa aagctcccct attttcttag atacatcttc aagttggctg gtattattgg
     9901 aatcaatacc atctagcagt ttattaattc gagactgaat atggttcgtc tcaacaaaaa
     9961 tctggtatga agcagtcgta acatgaaaac cgtctggcac agggatgcct gctgtcaata
    10021 gttttgataa agacatccct tttccaccaa caatttcaat ggttgcttgt ttatgttcca
    10081 gtggcaagac ataataaatc ataatcattc acctccatca ttcataattc cgtgcagaaa
    10141 tatattcatt gtttcatcca acattttttc cgaactatcc aatggtcgtg acgtgtagct
    10201 gattgataac atggagttaa ttaacaaacg tgtcacaaga gcggtatccg ttttgcgaaa
    10261 gatgcctgtg gtcacaccat tatcaattac cgattttata atatcttgat atgcataacg
    10321 agcatcttta agtctctttc gatactcttc ttctaaataa tcagattctg tatttaacca
    10381 catcagtaca gttctatact gctctggaaa tctaagatga ttaagcatga tttttctaag
    10441 gcactgttgt ggtgaaggtt caccatcaat aatcctatga acttgttgga tagttttttc
    10501 tatttctttc tcaactgcat atacaacaat ctcgtctttc gttttgaaaa aatcgtatag
    10561 acttgacttt cccatgttgg ctaaaactgc aatttctctc attgatgttt tttggaatcc
    10621 attttcagcc ataagactca aagcaacagc aactattttt tctcggcgtt ctgcttgttg
    10681 ttcgggtgta agcacaattc cttttggcat agggcgatac ctccttttag cgaccactgg
    10741 tcgtttcttt tttatttatc atacagcgac caacggtcac ttgtcaaggt taattttttt
    10801 cattgtatat ggtactcgag ataaaaatgt tcattttaga aattgctcta tttaagtaga
    10861 aataggcttc atcattagaa aacaagacta taaatttgag atatttatca tgttcaaatt
    10921 tcatcaatat caaagtttaa gatattaata aaaaaagaat tactaagaaa taacatataa
    10981 agattcaaaa aaggagttga acttaaaatt caattacaaa aaatcaaatt taagacaact
    11041 cctttattct ttatctctac tattctttat ctctatttat ttattacaac tccctaacat
    11101 ttaccactac tgccttaggt ctagtcatag cctcgattga atacttaaca ccttgagttc
    11161 ccataccaga tgcctttaca cctaaaaatg ggaagtggtc tggacctctt tcagtcttat
    11221 tatttatttg aacagtacca acttcaagtt tatcagctat ataaaatgcc ttatcaatat
    11281 cacttgtaaa tactgatgat tgaagcccat actctgattg attagcaatt tcaattgctt
    11341 gatttatatc tttaactctt ataattggaa gtactggacc aaatggttct tcccaagcaa
    11401 ttttcatatc aacatttaca ttatctaaca atgttggata gaataaatta ttttttctaa
    11461 cattgcctgt tattaacttt gctcctttat gtaatgcatc atcaaccaac ccttgaacaa
    11521 aatcagttgc tttattatct ataagaggag tgataactac ttcatccatt ggatttccaa
    11581 ttgtcaactt ctctaccaat ggctttattt ttccgactaa tttatccgcc acactctctt
    11641 gtactaaaat tctctttact gccgtacatc tttgtcctga atatgaatac gctccagata
    11701 ctatattctt agctgcaaaa tctaagtctg catcttctaa tactatagcc gcatcttttc
    11761 caccaagctc caataataat ggtaccattc cagatatttt agatatatgc tgaccaactt
    11821 cagtactacc agtaaagtta ataaaattaa ttcctttatg cgttacaaca taatctccta
    11881 tctcactacc cctacctgta atagtattaa gtactccatc tggtatccca gcttttctca
    11941 taatttctac cacatgaagt gcgctaatag ccccttgtgt agcaggtttt aatacaactg
    12001 catttccacc aataagtgct ggagcaatct ttgacattga taaatttaca ggataattaa
    12061 aaggagatat agctaaaaca gtacctaatg gaacccttga aacataagac atcttatttc
    12121 ttgttccacc agggaaatta tctccactaa tggcttcacc ctccatattt tttcccacat
    12181 cagctgtgta tcttaaaaaa tctgctgttc tctcaacttc tgcccttgca gattttatgt
    12241 ctttggctat ttcaagtacc agtatattag ctatctcatc tatattttct aacaataaat
    12301 cagcagcctt atgaaatata ttggctctct tatatacagg catttcagcc catactttta
    12361 tactctcttt tgtgtttttt ataacctcat ctacctcatg ttttgtcata gattgtactt
    12421 tcccaacaag agaattatct attggtgagt aaatttctat tggctttctc gaattagatt
    12481 ctacccattt tccatttatt aaatttttat atacattttc ttttgtttta agttcattaa
    12541 acatattttt attcctctct ctgatataac tttgtgtatt taaattatag ccatttattc
    12601 gttatgtaaa catttctttt tttcataaac gtttacctat aaaaaaattt taagttaacg
    12661 tttttctaca ttcttctatt ttaataacat actcgctcca aatctatata ggtcacactt
    12721 taatatcaat atactaatat accaatatac caatatacca atataccaat ataccaatat
    12781 aaatattata aacataaatc acttgacaaa tttataagta gacaatatta tatatctatg
    12841 acttaaaata tttttaaagt catagatatc atatatagat agaaaggatt gataaaaatg
    12901 gctaaaagtt ttacagaaat agaaaaagac aatataagaa aaagactaat ttcagaatgt
    12961 gaaatcaact ggtctaaata tggatacaaa aaaactaata ttgatgaact ttgttcaaaa
    13021 tcaggaattg caaagggttc attctacaca ttctttgatt caaaagaaaa gttatttttt
    13081 gaagtattaa atggaatcca aaacagactt atatcatcag tagatgaaat tttaagtaac
    13141 atgcctccaa aagaaggctt tgcaaaagcc ttaaagatgt tgtatcgatt atatgataaa
    13201 aacccattct tatattcacc aaataatact gattacatca ctttattgaa taagatacct
    13261 aaagagatgc tttcacaact tgaatacagc aatgtacaaa gtttttatag cttaattgaa
    13321 agacataatc tcaagttaaa aatagagaaa gaaaaagcct ttggtgtttg caatgcccta
    13381 ctgtcaagcc tattgctaaa agaagatatt ggatatgact acattgaagt atttgatttt
    13441 atggtagaca atcttgtaga acacatactt gagtaataat ttaaaataaa ttttctaaac
    13501 atttctttat aactaggagg agtaatatga ttgaattaat acaaagacta aatgatatta
    13561 tttacaaaat aaatgataaa ctaaatatcc acacaaaact tgtagaccct agcagtgagc
    13621 tcatgccact ttactctatg ttatctataa tcgtttctat atttctaata atattaggta
    13681 ttaaagtaag aaaaaaattc cttataataa ttgctattat atcaattatt ataaatattt
    13741 taataatctt agataggtag gtacatatat ggtaaaatcc tcgaacactt ttaataaaaa
    13801 cttcaacttg atgatattag gtcaaataat ctcattgttt ggtgcatcaa tacttaaatt
    13861 tgctttatct ttatacatac ttgatataac tggtaaagca gaaatatttg ctactatact
    13921 agcagtatct tcaatcccaa ttatagtatt ctcccctatt ggtggagcta ttgcagatat
    13981 attcaacaga agaaacttaa tggttatttt tgatttttca agtagtctta cagtactaat
    14041 cttagcagta ttcttattca acaataatgg ttcaatatta cttgtaggaa ttattatgac
    14101 catattatca gtcataagca caatgtatca accaactgtt cagtcaagta cacccctttt
    14161 agttgataat gagcatttaa tgaatgcaaa tggtattgta gctggagttg catctcttac
    14221 aaatattgca ggacctgtat taggaggtgt cttgtatggt gtgattggaa ttaatgcaat
    14281 tatagttata agttgtgtaa gtttctttct atctgcaatt atggagatat ttatacagat
    14341 tccttttatc aaacaagagc aaaacagcaa cattataaaa actatattta ctgatataaa
    14401 ggatggtatt gttcatatat gtaaagaaaa tagatttata ctaaaaatac tttttttagc
    14461 tatagcaata aacttatttt taagctctat gttaatagtt ggtatcccct atatagtaaa
    14521 aatcactatg ggagctagta acttcttata tggtctagca gaaggagcaa tttcttttag
    14581 ttcactggta gctgctgtta gtattggtat tttctcaaaa catctaaaaa tcactaattt
    14641 gcatatttcc tttattatat gtgcagttat gttcatacca atggcggttt cagtatatcc
    14701 atttatatta aacacaggat ttccagttcc atttttaatc tttatagtat catctatgct
    14761 aatatttttt acaacgactc ttatctcaat atatgttata acagtcacac aattaaaaac
    14821 tccaaatgaa ctcttaggaa aagtaatgtc aattcttttt gcaggaacag caattgcaat
    14881 gccccttggt caggttatgt atggtaaact ttttgattta ttatcagata gagtgtacat
    14941 cattatacta ggagttggat ttattacatt acttatagca tttgtatcaa agataacatt
    15001 gaggaacgaa aatctttaga tacaaagaat ttagatataa agatttaatt ttcactaatt
    15061 tctgaattta aatgcaaaat tgtgtatcag tatgttgacg ttttagaaat tgattgatat
    15121 aatcaatgga aaataaactt tataaaaatt caaaatattc agctagagga gtgataaaaa
    15181 tgagttacat gccaacttta gaacaagcat gggaaatatt aagaaaatac aataaggaag
    15241 aatttcatat aagacatgct caaattgtat ctggagttat gagatactat gcaaaggagt
    15301 acgaccctga aagagtagaa ttttgggaaa tagttggact tttacatgat ttagattttg
    15361 aaatgtatcc tgatgaacat tgtgttaaac aaagagaatt aatgacagag cttgatttag
    15421 ataaatcaat aatcgattct acaataagtc atggatatgg attaactggt tcagatgtta
    15481 aaccagagca atttatggag aaagtattat ttgctgtgga tgaacttact ggtttaattg
    15541 gtgctgctgc aataatgcgt ccttcaaaga gcgtttctga tttagaatta aaatctgtta
    15601 agaagaaatt taaagataaa tcatttgctg ctggctgttc tcgagacgtt ataagaagtg
    15661 gtgcagaaat gcttggatgg gaacttgata agcttatcca aacaactata gaagctatga
    15721 gaagcttgat tccagagatg gcaatatagc tcctccatac atataccata gaagttacat
    15781 ctttaaagag catttctctt tttgatgcaa cttcttttta tattttgtag aataaaaagt
    15841 ttaatatttt aaactcacta tataatctat aataaatact ataaataata taatgtataa
    15901 tagtcataaa ctttctaacc ttaaaagttt ctaataatca ataaacaatt ctaatataca
    15961 aatgtcatta tatgatttaa ttatatatct tcaatttata tattaaaata aatatatata
    16021 tattaaattc ttatacacca
//
LOCUS       DAEPHU010000087        15677 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 01A10CD0081
            SAMN05941466-rid12468953.denovo.087, whole genome shotgun sequence.
ACCESSION   DAEPHU010000087 DAEPHU010000000
VERSION     DAEPHU010000087.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941466
            Sequence Read Archive: SRR6291087
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 15677)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15677)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068158.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 22:43:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,892
            CDSs (total)                      :: 3,805
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 87
            rRNAs                             :: 8, 1, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 55
            CDSs (without protein)            :: 55
            Pseudo Genes (ambiguous residues) :: 0 of 55
            Pseudo Genes (frameshifted)       :: 21 of 55
            Pseudo Genes (incomplete)         :: 28 of 55
            Pseudo Genes (internal stop)      :: 16 of 55
            Pseudo Genes (multiple problems)  :: 8 of 55
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15677
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941466-rid12468953.denovo.087"
                     /strain="01A10CD0081"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            <1..196
                     /locus_tag="KR231_003158"
     rRNA            <1..196
                     /locus_tag="KR231_003158"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
     gene            324..440
                     /gene="rrf"
                     /locus_tag="KR231_003159"
     rRNA            324..440
                     /gene="rrf"
                     /locus_tag="KR231_003159"
                     /product="5S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00001"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00001"
     gene            448..522
                     /locus_tag="KR231_003160"
     tRNA            448..522
                     /locus_tag="KR231_003160"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:480..482,aa:Asn,seq:gtt)
     gene            528..613
                     /locus_tag="KR231_003161"
     tRNA            528..613
                     /locus_tag="KR231_003161"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:562..564,aa:Leu,seq:taa)
     gene            629..704
                     /locus_tag="KR231_003162"
     tRNA            629..704
                     /locus_tag="KR231_003162"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:662..664,aa:Met,seq:cat)
     gene            712..786
                     /locus_tag="KR231_003163"
     tRNA            712..786
                     /locus_tag="KR231_003163"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:745..747,aa:Glu,seq:ttc)
     gene            801..874
                     /locus_tag="KR231_003164"
     tRNA            801..874
                     /locus_tag="KR231_003164"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:833..835,aa:Gly,seq:tcc)
     gene            880..955
                     /locus_tag="KR231_003165"
     tRNA            880..955
                     /locus_tag="KR231_003165"
                     /product="tRNA-Val"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:913..915,aa:Val,seq:tac)
     gene            961..1037
                     /locus_tag="KR231_003166"
     tRNA            961..1037
                     /locus_tag="KR231_003166"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:995..997,aa:Asp,seq:gtc)
     gene            1048..1122
                     /locus_tag="KR231_003167"
     tRNA            1048..1122
                     /locus_tag="KR231_003167"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1080..1082,aa:Gly,seq:gcc)
     gene            1132..1205
                     /locus_tag="KR231_003168"
     tRNA            1132..1205
                     /locus_tag="KR231_003168"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1166..1168,aa:Arg,seq:tct)
     gene            2189..3028
                     /locus_tag="KR231_003169"
     CDS             2189..3028
                     /locus_tag="KR231_003169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00159 family protein"
                     /protein_id="HBH0005510.1"
                     /translation="MLDINSFLNGFFNIILRMSIYDLIDISIVAYIFYKIFMFIKDTR
                     AEQVFKGIIFLLLATQLSNTFKLHTVYWISLKALDYGVIAALIIFQPEFRAGLEHIGR
                     AKFNLFGKNVNTSEETLNRNIEEIVEALYSLSRQKIGALIIMERETRISDIINTGTII
                     DAEISRQLLINIFIPNTPLHDGAVVIRDSKVKAAACFLPLTESKDLSKDLGTRHRAGI
                     GVSEVSDCITLIVSEETGGVSIAKAGKLYRDISRERMMNILRSNLKTNTETRSFFKGG
                     IFK"
     gene            3025..4206
                     /locus_tag="KR231_003170"
     CDS             3025..4206
                     /locus_tag="KR231_003170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0005511.1"
                     /translation="MINRLKNNTKIKIISFLSAIALWMYVMAVVDPEETKGFEDIPVS
                     ISNMSDLKDKNLVIYPDEKLTADVYIKGSLSKVQSVKKEDIHVYGTIEDPIQGQKEVY
                     LKANIPQGVTLEFKHDVLVVNLEKNIKEKRDIKVEVSGNSKRNINKIELSKEFVDVSG
                     PRTLVKEVKSVRANLDVGNETDDFSKKLQLIPLNSDGTKVEGVTLSSSFVTAKIELLK
                     EKIVPIRVSLNDNKDNDVLKNYKLSKEQVTIKGKKEDIDKISYIKTKPIDLADLANGE
                     EKEVSLEIPEGITLEDSSITIKLNDTKQLSAEFLYNAGDIELRNIPTNMDNPNVISDV
                     DIKVVVESTEDLSKLNKKDISLYIDLSQGPEEDSKYKIKYETTYQFKKINIEPNIVEV
                     E"
     gene            4510..5412
                     /gene="ptb"
                     /locus_tag="KR231_003171"
     CDS             4510..5412
                     /gene="ptb"
                     /locus_tag="KR231_003171"
                     /EC_number="2.3.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425473.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate butyryltransferase"
                     /protein_id="HBH0005512.1"
                     /translation="MRSFEEVIKFAKERGPKTISVACCQDKEVLMAVEMARKEKIANA
                     ILVGDIEKTKEIAKSIDMDIENYELIDIKDLAEASLKSVELVSQGKADMVMKGLVDTS
                     IILKAVLNKEVGLRTGNVLSHVAVFDVEGYDRLFFVTDAAMNLAPDTNTKKQIIENAC
                     TVAHSLDISEPKVAAICAKEKVNPKMKDTVEAKELEEMYERGEIKGCMVGGPFAIDNA
                     VSLEAAKHKGINHPVAGRADILLAPDIEGGNILYKALVFFSKSKNAGVIVGAKAPIIL
                     TSRADSEETKLNSIALGVLMAAKA"
     gene            5434..6513
                     /gene="buk"
                     /locus_tag="KR231_003172"
     CDS             5434..6513
                     /gene="buk"
                     /locus_tag="KR231_003172"
                     /EC_number="2.7.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="butyrate kinase"
                     /protein_id="HBH0005513.1"
                     /translation="MSKIFKILTINPGSTSTKIAVFDNEDLVFEKTLRHSSEEIGKYE
                     KVSDQFEFRKQVIEEALKEGGVKTSELDAVVGRGGLLKPIKGGTYSVSAAMIEDLKVG
                     VLGEHASNLGGIIAKQIGEEVNVPSYIVDPVVVDELEDVARISGMPEISRASVVHALN
                     QKAIARRYAREINKKYEDINLIVAHMGGGVSVGAHKNGKIVDVANALDGEGPFSPERS
                     GGLPVGALVKMCFSGKYTQDEIKKKIKGNGGLVAYLNTNDAREVEERIEAGDEKAKLV
                     YEAMAYQISKEIGASAAVLKGDVKAILLTGGIAYSKMFTEMIADRVKFIADVKVYPGE
                     DEMIALAQGGLRVLTGEEEAQVYDN"
     gene            6503..7180
                     /locus_tag="KR231_003173"
     CDS             6503..7180
                     /locus_tag="KR231_003173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HBH0005514.1"
                     /translation="MITNDKRIRIITGHYGSGKSEFAMNYVVKLRDMVSGKVAIADLD
                     VVNVYFRTREKKELMKSLGIQPIDSSINAPTLDLPAVSAEVMSPMVDHSYNSVIDLGG
                     DNVGARVIGRFSHLLKEGDYDMLFVINANREKTQTSEEVIQYIKEIEKSSKLKVTGLI
                     NNTHLIRFTTIDDVLRGQKVAKEVSEKCNIPIRYVACLENLVEQLPKDLEGEIFPIKL
                     YMREDWM"
     gene            7223..7438
                     /locus_tag="KR231_003174"
     CDS             7223..7438
                     /locus_tag="KR231_003174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S binding protein"
                     /protein_id="HBH0005515.1"
                     /translation="MAKGKVSFNQERCKGCGLCVEACPVKIIQLDSNVINKKGYNPAT
                     VFEMEKCIGCASCATMCPDVVITVERD"
     gene            7467..8546
                     /locus_tag="KR231_003175"
     CDS             7467..8546
                     /locus_tag="KR231_003175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-methyl-2-oxobutanoate dehydrogenase subunit
                     VorB"
                     /protein_id="HBH0005516.1"
                     /translation="MAKILMKGNEAFGKAAIEAGCKYFFGYPITPQSELPEYLSRELP
                     KIGGAFVQAESEVSAINMVYGGAGAGARVMTSSSSPGVALKQEGITYAVGAEVPCVVL
                     NVMRGGPGLGSIQPSQADYFMSTRGGGNGDYRTPVFAPATVQEAVDMIMEAFDVADYY
                     RSPVMVVADGMIGQMMEPVEFRAPEKKRELPPKDWATVGTKGKRKPNVINSLYLEPEV
                     LEDHCWHLQEKFDAMEKNEVQYEMYKTEDAEFVFAAYGTTSRVVKSAIDILREEGIKA
                     GLIRPKVLWPFPFEAFNQIPNARNILTVEMSMGQMVEDVKMAVEGKLPVYFHGRPGGM
                     TPTPAEIVEKAKKIIAGELVAGGAR"
     gene            8546..9298
                     /locus_tag="KR231_003176"
     CDS             8546..9298
                     /locus_tag="KR231_003176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-oxoglutarate oxidoreductase"
                     /protein_id="HBH0005517.1"
                     /translation="MAVVFKKTEGLQDTQTHYCPGCTHGIIHRLVGEVLEELGVLGDA
                     VGVVPVGCSVLGYKYFNCDTQEAAHGRAPAAATGIKRVHPENTVFTYQGDGDLASIGT
                     AEIVHAAARGEKITTIFVNNTTYGMTGGQMAPTTLVGQRATTAQSGRNAETQGYPIRV
                     SEMLATLTGAVFVERVAVDTPAHVRQAKKAIKKAFQVQQAGLGFGIVEVLSTCPTNWG
                     LAPNDALQWLRDNMIPYYPLGNFKNVEVEEVK"
     gene            9299..9856
                     /locus_tag="KR231_003177"
     CDS             9299..9856
                     /locus_tag="KR231_003177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-oxoacid:acceptor oxidoreductase family
                     protein"
                     /protein_id="HBH0005518.1"
                     /translation="MSTARVICAGFGGQGVMSMGQLLTYAGMLEGKEVSWLPSYGPEM
                     RGGTANCAVTVSNEPVGSPLITDDATAAILLNIPAFEKFKDDVIPGGKIIVNSSLIKE
                     KVDRTDVDVYYIPANELAAELGNDKVANMIMLGAYLKVSDTVDIESVLEAFKKVFGPR
                     KEKFVPLNREALQKGMDATCSKATN"
     gene            10026..11372
                     /locus_tag="KR231_003178"
     CDS             10026..11372
                     /locus_tag="KR231_003178"
                     /EC_number="5.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglucosamine mutase"
                     /protein_id="HBH0005519.1"
                     /translation="MRKYFGTDGVRGVANTELTCDLAYKLGRAGGFVLAQGDHRVKVV
                     VGKDTRISGDMLEASLIAGLMSVGCDVITVGIIPTPAVAYLTRKYGADCGVVISASHN
                     PVEYNGIKFFNKNGYKLDDEIELKIEEYIDDIDKIDCLPIGENVGRKLHEHCAQRDYV
                     DYLKSIISTDFKGLKVVLDCANGASYKVAPIVFDELGASVISINSSPDGNNINYKCGS
                     THPEQLQRAVLEHNADLGLAYDGDADRLIAVNEKGQIVDGDHIMILSALNLKKNNKLA
                     QDTLVVTVMSNIGLTIAAKENGINLSTTAVGDRYVLEDMVKNGYNLGGEQSGHMIFLD
                     YNTTGDGVLSSLILANIILQEKKPLSEIASIMSQYPQVLVNATIKNENKNKYMEYPEI
                     KTEIERIESILDGNGRVLIRPSGTEPLVRVMLEGKEEGQIKELATNLANLIQEKLS"
     gene            11639..13471
                     /gene="glmS"
                     /locus_tag="KR231_003179"
     CDS             11639..13471
                     /gene="glmS"
                     /locus_tag="KR231_003179"
                     /EC_number="2.6.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003401499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine--fructose-6-phosphate transaminase
                     (isomerizing)"
                     /protein_id="HBH0005520.1"
                     /translation="MCGIVGYLGSRKAAEVIVEGLSKLEYRGYDSAGVAVNSSNEKEL
                     NIRKFKGRLSVLAEDLEKNPIDGNLGIGHTRWATHGEPSDVNSHPHFNQAKTIAVVHN
                     GIIENYMEIKEELISEGVKFESQTDTEVIAHLVDKYYEGNLLDAVYKTISKLRGAYAL
                     GVICKEHGNELVAVRKDSPLVVGVGEGENFIASDIPALLKYTRDVYFLENGEVVHLKD
                     ENVTVYDSNRNLVEKEVFHVTWDVEAASKGGYDYFMSKEIHEQPTGVRETLERRLDDN
                     GNIILDSINISKEDLEKINKVYIVACGTAYNAGLLGKYAIEKFVNIPVITDIASEFRY
                     SDPFVDENSLVILVSQSGETADTLAVLRDSKAKGARILSITNVVGSSIARESDDVFYT
                     WAGPEVAVASTKAYTTQITSLYMIALDFAIKKGTITREFYDSMISKMKEIPSKIQEIL
                     DNEEYIKEVAKTVVSSEHAFYLGRGIDYSLAMEGSLKLKEISYIHAEAFAAGELKHGT
                     IALIEKGTPVIAIATQEKLFEKMVSNMEEVRARGAYVVAIAQSHNKDVEKAADKIIYI
                     PNSDDILSPILAVVPMQLLAYHVSVLRGCDVDKPRNLAKSVTVE"
     gene            13922..15217
                     /locus_tag="KR231_003180"
     CDS             13922..15217
                     /locus_tag="KR231_003180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860639.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiosulfate sulfurtransferase"
                     /protein_id="HBH0005521.1"
                     /translation="MTNDFKKEKKEDYFVNLKAISTEVLQEKVQDNAWVIVDTRLNDA
                     YNGWKLDGVKRGGHIKGAVDFSANWLSVYSDRKDEVLEQALKTKRIDLDKNIVLYDAN
                     GKDALVVADYLSKKGYKYLYKYDIKQWADNENLPMERYKNYQMIVPAFIIKDILDGKI
                     PETFEDSKNIKMIEASWGEESYTKGHIPTSVHVNTDIIEPPPTWMLDNDDNLIKFALD
                     YGLTKDDTVIVSSSTPMASYRLAVILRYIGVKDVRVLNGGTNSWLSAGYELEFTSNPK
                     HSCTNFGADIPVNSQLVVTTSELRQKLKEKNKFILVDNRTWDEHIGKVSGYTYYDKKG
                     RIPGALYGHSGSDSVSLEEYRNIDNTMRNKYEILEMWDKENIDVNRQLIFMCGSGWRA
                     AEVLTYANVIGVENTSLYSDGWMGWSLDNSNLIEVGEHK"
BASE COUNT         6077 a         1851 c         3118 g         4631 t
ORIGIN      
        1 ctgccaaggg catggctggg tagctatgta cggaatggat aagcgctgaa agcatctaag
       61 cgcgaagcca acttcaagat aagatttccc accgcaaggg taagacccca gaaagactat
      121 ctggttgata ggtcgaaggt gtaagtgcag caatgtattt agcttatcga tactaatagg
      181 tcgaggactt gaccaatatt tatttgatgt tcattcatta agatatatgt gtagttttta
      241 gagtgctaac tctaaagaaa ctagtattgc taggttctat aaacttatta aaaacttaat
      301 agaaatatta agcataaaga ttatgtggtt acaatagcag agaggataca cctgttccca
      361 tttcgaacac agaagttaag ctccctagcg ctgatggtac ttggtgggaa actgcctggg
      421 agagtaggac gtagccacgt taaatgttcc aaggtagctc aacggtggag caaccggctg
      481 ttaaccggta ggctgtgggt tcgagcccca cccttggagc caaaaaagcc gaagtggcgg
      541 aactggcaga cgcacaggac ttaaaatcct gcgggactta cctctcgtac cggttcgatt
      601 ccggtcttcg gcacttataa aacaatatcg cggggtggag cagttggcag ctcgtcgggc
      661 tcataacccg aaggtcgtag gttcaagtcc tgcctccgca accattaaaa cggctcgttg
      721 gtcaagaggt taagacaccg ccctttcacg gcggtaacag gggttcaatt cccctacgag
      781 tcaccaattc aattaaatat gcgggtgtag ctcaatggta gagttctggc cttccaagcc
      841 agctgtgagg gttcgatccc cttcacccgc tccaaaaatg ggaccatagc tcagctggga
      901 gagcacctgc cttacaagca gggggtcaca ggttcgagcc ctgttggtcc caccattcgc
      961 ggcctggtag ttcagttggt tagaatgcca gcctgtcacg ctggaggtcg agggttcgag
     1021 ccccttccag gtcgccaaat taaataagcg ggaatagttc agtggtagag cgcaaccttg
     1081 ccaaggttga agtcgcgagt tcgaatctcg tttcccgctc cataataact tgggtgcata
     1141 gctcagctgg atagagcaac gcccttctaa ggcgtgtgtc cggggttcga atccctgtgc
     1201 gctcattaag aaaagtttac tataaattat agtaaacttt tatattgttt aaaaagacac
     1261 aggaaacatg tatattacct gtgtcttttt atttataaac tttaaactat gtaaaaatta
     1321 cagtatattc taatagagtt acagtatatt cattaatatt gtaaacatac ggagggtaat
     1381 gtataatagt ctacaagatg tttatgaagg catcagttaa atataataaa tataactaat
     1441 tagtaagagt tatatacatt atattgtata ctttatggta tttatatatt gaaataactt
     1501 atgaaattat ttataaagag attcatgagc atatttttgt ctaaacaata agtataagaa
     1561 attataaaaa gttagagact atagtgaatt tacaatttaa tgtaatattt ataagttata
     1621 ctaaataaat tattatactg tgaaatggat atataacttt aggtattgtg tattattttc
     1681 actgtaggag attatatcta gttatacata ataagtttta atgatagttt atagtaagat
     1741 attaaaataa atttatctaa tctagatatg aaataagtta ttactttaat ataaaaatga
     1801 atctaatgga ataatattga tgataagtaa tatttagatt ttgtatttgt ttatagttaa
     1861 taagtggatt atagaattta taataattaa tatatattaa acaaagatat attaagatat
     1921 tttagaacat aaaactgaat taaggcgcga gtactatttt gtattcgcgc cttgatggtt
     1981 tgagttattt gagtaaaaac taactttaat aagaaatatg tatttattaa gttgatattt
     2041 ttaatgtgtt tagagattat ttaacaatct ccaaatataa aactagaatt atttacataa
     2101 aagttaaata gtttgtatag agttagattt atatagtata atacttagtg taaataatta
     2161 agaagttatc aaacaggagg ataaaactgt gttagatata aattcttttt taaatggatt
     2221 ttttaatata atattaagaa tgagtatata tgatttaatt gacatatcta tagtagcgta
     2281 tattttttac aaaatattta tgtttataaa agatacaaga gcagaacaag tgtttaaagg
     2341 tataatattt cttttattag caactcaact tagtaacacc tttaaattgc ataccgttta
     2401 ttggatatct cttaaagctt tagattatgg agttatagct gctcttataa tttttcaacc
     2461 agaatttaga gcaggacttg aacatatagg aagagcaaag tttaatttat ttggaaagaa
     2521 tgtaaatact tctgaagaaa ctctcaatag aaatatagaa gaaattgtag aagctttata
     2581 ttcactttct agacaaaaaa taggagctct tatcataatg gagagagaaa ctagaataag
     2641 tgatataata aatacaggaa ctattattga tgctgaaatt tctaggcaac tattaataaa
     2701 tatatttata ccaaatacac cattacacga tggagctgtt gtaattagag attctaaggt
     2761 aaaagcagct gcatgttttt tgccattgac agaaagtaag gatttaagta aagatttggg
     2821 cactagacat agagcaggaa taggggtaag tgaggtgtct gactgtataa ctttgattgt
     2881 atcagaggaa acaggtggcg tatcaattgc taaagcaggt aagttatata gagatatttc
     2941 tagagaaaga atgatgaata tattacgtag taatttaaaa acaaatacag aaacaagaag
     3001 ttttttcaaa ggtggtatat ttaaatgata aatagactaa aaaataatac caaaataaaa
     3061 ataatatcat ttttaagtgc aattgcatta tggatgtatg ttatggctgt agttgaccct
     3121 gaagaaacta aagggtttga agatatacct gtatctataa gtaatatgag tgatttaaag
     3181 gataaaaatc ttgttatata tccagacgaa aaattaacag cagatgtata tataaaaggt
     3241 agtttatcaa aggtacaaag tgttaaaaaa gaagatatac atgtatatgg aaccattgaa
     3301 gacccaatac aaggacagaa ggaagtatat ttaaaagcaa atattcctca aggtgttact
     3361 ctagaattta agcatgatgt tttagtagta aatcttgaaa aaaacataaa agaaaaaaga
     3421 gatataaagg tagaagtaag tggaaattca aaaagaaata taaataaaat tgaacttagt
     3481 aaggaatttg tcgatgtatc aggtccaaga actctagtta aagaagtcaa aagtgtaaga
     3541 gctaatctag atgttggtaa tgagacagat gatttttcta aaaaattgca attaatacca
     3601 ttaaatagtg atggaactaa ggttgaagga gtaacattaa gttcatcctt tgtgactgca
     3661 aagatagagc tattaaagga aaaaattgtc ccaataagag taagtctaaa tgataataaa
     3721 gataatgatg tactgaaaaa ctataaatta agtaaggaac aagttacaat aaaaggaaag
     3781 aaagaagata tagacaaaat aagttatatt aagacaaaac ctattgactt agctgatttg
     3841 gctaatggtg aagaaaaaga agttagctta gaaattccag agggtataac tcttgaggat
     3901 agctctataa caattaaatt aaatgataca aaacaattga gtgcagaatt tttatataat
     3961 gcgggagata ttgaattaag aaatatccca acaaatatgg ataatccaaa tgtaatttct
     4021 gatgtagata taaaagttgt tgtagagtca acggaggatt tgagtaagtt aaataaaaaa
     4081 gatatttcat tatatattga tttatcacaa ggtcctgagg aagatagtaa atataaaata
     4141 aaatatgaaa caacatatca atttaaaaaa ataaatatag aacctaatat tgttgaagtg
     4201 gaatgaacaa atatttcgaa tatttagttg ttacaagatg cgacaaaaaa acctataaaa
     4261 ttaagtttgt taattttatg tttttgttgc atcttgttta ttttagttat attataaaat
     4321 aaggacaatg agatatttgt taaatctaaa aagcgctaga tatatgaaaa aagactgata
     4381 aatagattta aataaatatt ttgaattaaa tatttcaatt atctctagga aaacgttgct
     4441 gaacgagtta taatttaatt gagatataaa aagttctatt tcaaaaaatt caagatgagg
     4501 tggaaatgca tgagaagttt tgaagaagta attaagtttg caaaagaaag aggacctaaa
     4561 actatatcag tagcatgttg ccaagataaa gaagttttaa tggcagttga aatggctaga
     4621 aaagaaaaaa tagcaaatgc cattttagta ggagatatag aaaagactaa agaaattgca
     4681 aaaagcatag acatggatat cgaaaattat gaactgatag atataaaaga tttagcagaa
     4741 gcatctctaa aatctgttga attagtttca caaggaaaag ccgacatggt aatgaaaggc
     4801 ttagtagaca catcaataat actaaaagca gttttaaata aagaagtagg tcttagaact
     4861 ggaaatgtat taagtcacgt agcagtattt gatgtagagg gatatgatag attatttttc
     4921 gtaactgacg cagctatgaa cttagctcct gatacaaata ctaaaaagca aatcatagaa
     4981 aatgcttgca cagtagcaca ttcattagat ataagtgaac caaaagttgc tgcaatatgc
     5041 gcaaaagaaa aagtaaatcc aaaaatgaaa gatacagttg aagctaaaga actagaagaa
     5101 atgtatgaaa gaggagaaat caaaggttgt atggttggtg gaccttttgc aattgataat
     5161 gcagtatctt tagaagcagc taaacataaa ggtataaatc atcctgtagc aggaagagct
     5221 gatatattat tagccccaga tattgaaggt ggtaacatat tatataaagc tttggtattc
     5281 ttctcaaaat caaaaaatgc aggagttata gttggggcta aagcaccaat aatattaact
     5341 tctagagcag acagtgaaga aactaaacta aactcaatag ctttaggcgt tttaatggca
     5401 gcaaaggcat aattttaagg gggaaatagg caaatgagca aaatatttaa aatcttaaca
     5461 ataaatcctg gttcgacatc aactaaaata gctgtatttg ataatgagga tttagtattt
     5521 gaaaaaactt taagacattc ttcagaagaa ataggaaaat atgagaaggt gtctgaccaa
     5581 tttgaatttc gtaaacaagt aatagaagaa gctctaaaag aaggtggagt aaaaacatct
     5641 gaattagatg ctgtagtagg tagaggagga cttcttaaac ctataaaagg tggtacttat
     5701 tcagtaagtg ctgctatgat tgaagattta aaagtgggag ttttaggaga acacgcttca
     5761 aacctaggtg gaataatagc aaaacaaata ggtgaagaag taaatgttcc ttcatacata
     5821 gtagaccctg ttgttgtaga tgaattagaa gatgttgcta gaatttctgg tatgcctgaa
     5881 ataagtagag caagtgtagt acatgcttta aatcaaaagg caatagcaag aagatatgct
     5941 agagaaataa acaagaaata tgaagatata aatcttatag ttgcacacat gggtggagga
     6001 gtttctgttg gagctcataa aaatggtaaa atagtagatg ttgcaaacgc attagatgga
     6061 gaaggacctt tctctccaga aagaagtggt ggactaccag taggtgcatt agtaaaaatg
     6121 tgctttagtg gaaaatatac tcaagatgaa attaaaaaga aaataaaagg taatggcgga
     6181 ttagttgcat acttaaacac taatgatgct agagaagttg aagaaagaat tgaagctggt
     6241 gatgaaaaag ctaaattagt atatgaagct atggcatatc aaatctctaa agaaatagga
     6301 gctagtgctg cagttcttaa gggagatgta aaagcaatat tattaactgg tggaatcgca
     6361 tattcaaaaa tgtttacaga aatgattgca gatagagtta aatttatagc agatgtaaaa
     6421 gtttatccag gtgaagatga aatgattgca ttagctcaag gtggacttag agttttaact
     6481 ggtgaagaag aggctcaagt ttatgataac taatgataaa agaataagaa tcataactgg
     6541 tcactatgga agtggtaaaa gtgaatttgc gatgaactat gttgttaagt taagagatat
     6601 ggtttctggc aaagttgcta tagccgattt agatgtggta aatgtatact ttagaactag
     6661 agaaaagaaa gagttaatga aatccttagg tatacaacca atagatagct caattaatgc
     6721 tccaacatta gatttaccag cagtatcagc agaggtaatg tctcctatgg tagaccattc
     6781 atacaattct gttatagatt taggtggaga taatgtaggt gctagggtta taggaagatt
     6841 tagtcatttg ttaaaagaag gcgattatga tatgcttttt gtaataaatg caaataggga
     6901 gaaaactcaa acttctgaag aagttatcca atatataaaa gaaatagaaa aatcttctaa
     6961 attaaaggta acaggtctaa ttaataatac tcatcttatt aggtttacta ctattgatga
     7021 tgttttaaga ggtcagaaag ttgcaaaaga agtttctgaa aaatgtaata taccgataag
     7081 atatgttgca tgtttagaaa atcttgttga acagttacca aaagatttag aaggagaaat
     7141 ttttcctata aaattatata tgagagaaga ctggatgtag tttgagctca aatatataga
     7201 aagtttaagg aggcttaggt aaatggctaa aggaaaagta tcttttaatc aagaacgttg
     7261 taaaggttgt ggattgtgtg ttgaagcatg tccagtaaaa atcatacaat tagactcaaa
     7321 tgtaataaac aaaaaagggt ataacccagc aactgttttt gaaatggaaa aatgcatagg
     7381 atgtgcaagt tgtgcaacta tgtgtccaga tgtagttata acagtagaaa gagattaatt
     7441 taattaatat ttaaggggga attttaatgg ctaagatact tatgaaaggt aacgaagcat
     7501 ttggaaaagc agctatagaa gctggttgca aatatttctt cggttaccca ataactccac
     7561 aaagtgaatt accagaatat ttatcaagag agttacctaa aataggtgga gcgttcgttc
     7621 aagctgaatc agaagtttct gcgataaaca tggtttatgg tggagcaggt gcaggagcaa
     7681 gagttatgac ttcttcatct tcaccaggag ttgctttaaa gcaagaaggt ataacatatg
     7741 cagtaggagc agaagttcct tgtgttgtac ttaatgtaat gagaggtggt ccaggacttg
     7801 gaagtataca accttcacaa gctgactact ttatgtctac aagaggtgga ggaaatggag
     7861 actacagaac tccagtattc gcaccagcta cagttcaaga agctgttgat atgataatgg
     7921 aagcttttga cgttgcagat tattacagat caccagttat ggtagttgca gatggtatga
     7981 taggtcaaat gatggagcca gttgaattta gagctcctga gaagaaaaga gaattgcctc
     8041 ctaaagattg ggcaactgtt ggaactaaag gaaaaagaaa acctaatgta ataaactctc
     8101 tatacttaga gccagaagta ctagaagacc attgttggca tttacaagaa aaatttgatg
     8161 caatggaaaa gaatgaagta caatacgaaa tgtacaaaac agaagatgct gaatttgtat
     8221 ttgcagctta tggaactact tcaagagtag taaaaagcgc aattgatata ttaagagaag
     8281 aaggaataaa agcaggtctt ataagaccta aagtattatg gccattccca ttcgaagcat
     8341 tcaaccaaat tcctaatgct agaaacatat tgactgttga aatgagtatg ggacaaatgg
     8401 tggaagatgt taaaatggca gtagaaggta aattaccagt ttacttccat ggaagaccag
     8461 gaggaatgac tccaacacca gcagaaatag ttgaaaaagc taaaaaaatt attgccggag
     8521 aattggttgc aggaggtgct agataatggc tgttgtattt aagaaaactg aaggattaca
     8581 agatactcaa actcactact gtccaggatg tacacatggt ataatccata gattagttgg
     8641 tgaagtatta gaagaactag gagtattagg tgatgctgta ggtgttgttc cagttggatg
     8701 ttcagtttta ggatataaat attttaactg tgacactcaa gaagctgctc atggtagagc
     8761 gccagctgct gctacaggaa taaaaagagt tcatcctgaa aatacagtat tcacttatca
     8821 aggtgatgga gacttagctt caattggtac tgctgaaata gttcatgcag ctgctagagg
     8881 agaaaaaata actactatat ttgtaaacaa tacaacttat ggtatgactg gtggacaaat
     8941 ggctccaact acattagttg gacaaagagc tactactgct caatcaggaa gaaatgctga
     9001 aactcaaggt tatccaataa gagtaagtga aatgttagct acattaacag gagctgtatt
     9061 tgtagaaaga gtagcagttg atactccagc tcatgttaga caagctaaaa aagctataaa
     9121 gaaagcattc caagttcaac aagcaggatt aggatttgga atagtagaag tattatctac
     9181 ttgtcctaca aactggggac tagctccaaa cgatgcttta caatggttaa gagacaacat
     9241 gataccatac tatccattag gaaatttcaa aaatgttgaa gttgaggagg tgaagtaaat
     9301 gtctacagct agagtaatat gtgcaggctt cggaggccaa ggtgttatgt ctatgggaca
     9361 attacttact tatgcaggaa tgctagaagg aaaagaagtt tcttggttac catcttatgg
     9421 accagaaatg cgtggaggta cagcaaactg tgcagtaact gtatctaatg agccagttgg
     9481 ttctccactt ataacagatg atgcaactgc agctatatta ttaaatatac cagcatttga
     9541 aaaattcaaa gatgatgtta ttcctggtgg aaaaataata gtaaatagtt ctttaataaa
     9601 agaaaaagtt gatagaacag atgtagatgt ttattatata ccagcaaatg aattagcagc
     9661 tgaattagga aatgataaag ttgctaacat gataatgtta ggtgcttact taaaagtatc
     9721 tgatactgta gatatagaat ctgtactaga agcattcaaa aaagttttcg gacctagaaa
     9781 agaaaaattc gttccattaa acagagaagc tttacaaaaa ggtatggatg ctacatgttc
     9841 taaagcaact aactaataaa gaaaaagatg tcaaaaaaaa gacaatagaa ttatttctat
     9901 tgtctttttt gctgataagt attaaaatat ttttatgact gaaattaagc ctataatgat
     9961 attttatgaa ctataaaaat ataatacaaa ttacaagctt ttcaattatg aaaggagaat
    10021 ctttagtgag aaagtatttt ggaacagatg gagttagagg agtagcaaat acagaactaa
    10081 catgtgattt agcatataaa cttggtagag ctggtggatt tgtcttagct caaggagacc
    10141 acagagtaaa agtagtagta ggtaaggata ctagaatatc aggtgatatg ttggaagcat
    10201 ctttaatagc aggacttatg tctgttggat gtgatgttat tactgttgga ataataccaa
    10261 cacctgcagt ggcatattta actagaaaat atggtgctga ttgtggtgtg gttatatctg
    10321 catctcacaa tcctgttgaa tataatggaa tcaaattctt taataagaat ggatataaat
    10381 tagatgatga aattgaattg aaaatagaag aatatataga cgatatagac aaaattgatt
    10441 gtcttccaat tggtgaaaat gtaggaagaa aattacatga acattgtgca caaagagact
    10501 atgtagacta cctaaaatca ataataagca ctgactttaa gggattaaaa gtagttttgg
    10561 actgtgctaa tggtgcgtca tataaagtgg caccaatagt gtttgatgaa ctaggagcaa
    10621 gtgtaatttc aataaatagt tcaccagatg gaaataatat aaactataaa tgtggctcta
    10681 cacatccaga acaacttcaa agggctgttt tggaacataa tgctgactta ggtcttgcat
    10741 atgatggaga tgctgataga ttaattgcag taaatgaaaa gggtcaaatt gttgatggag
    10801 accatataat gatattgagt gccttaaatt taaagaaaaa taataaattg gcacaagata
    10861 ctttggtagt tacagttatg agtaatatag ggttgacaat agctgctaag gaaaatggaa
    10921 taaatttatc tactacagca gttggagaca gatatgtttt agaagatatg gttaaaaatg
    10981 gatataatct tggtggagag caatctggac atatgatatt tttagattac aacactactg
    11041 gagatggagt gcttagttct ctaatacttg caaatataat cttgcaagaa aagaaacctt
    11101 tatcagaaat tgcatcaata atgagccaat acccacaagt attagtaaat gcaacaataa
    11161 aaaatgaaaa taagaacaaa tatatggaat atccagaaat aaaaactgag atagaaagaa
    11221 tagaatctat tttagacgga aatggtagag ttttgataag accatcagga actgagccat
    11281 tagttagagt tatgttagag ggtaaagagg aaggtcaaat aaaagaatta gcaacaaact
    11341 tagctaatct tatacaagaa aaattatcgt aatttaaagg gtattctcag atataaatac
    11401 tgaggacacc tttctaagcg ccagaactta gttatagaca taattattga gtaatatagg
    11461 aactaagttg acgaggtcag agttaatcga attgtcggcg gatgctctgc ggtgtgttta
    11521 ccatcgaaag acttctttaa ataataggag caatcctatg gacaaaggga agccaaagta
    11581 aacttatatg acctaactct taaaatatat aaataatatt tttaggagga cacaaataat
    11641 gtgtggaata gttggatatt taggaagtag aaaggcagca gaagttatag tagaagggct
    11701 ttctaagcta gagtacagag gttatgactc agcaggagta gcagttaata gttctaatga
    11761 aaaagaactt aatattagaa agtttaaagg tagactttct gtacttgcag aagacttaga
    11821 aaagaatcct attgatggaa atttaggtat agggcatacg agatgggcaa ctcatggaga
    11881 accatctgat gtaaactcac atcctcattt taatcaagcc aaaacaatag cagttgttca
    11941 taatgggata atagaaaact atatggaaat aaaagaagaa ttaatttctg aaggtgttaa
    12001 gtttgaatct caaacagata cagaggtaat agcacattta gtagataaat actatgaggg
    12061 taatttatta gatgctgtat acaaaactat atcaaaatta agaggagctt atgcattagg
    12121 tgttatatgt aaagaacatg gaaatgaatt agttgcagta agaaaagata gtcctcttgt
    12181 agttggtgtt ggtgaaggtg aaaactttat agcatcagat atacctgcat tattaaaata
    12241 tactagagat gtttatttct tagaaaatgg agaagtagtt catctaaaag acgaaaatgt
    12301 aacagtttat gactctaata gaaatcttgt tgaaaaagaa gtatttcatg taacttggga
    12361 tgtagaagct gcgtctaaag gtggatatga ctactttatg tcaaaagaaa ttcatgagca
    12421 accaacagga gtaagagaaa ctttagaaag aagacttgat gataatggaa atataattct
    12481 agacagtata aatatttcta aagaagactt agaaaaaata aataaagttt atatagtggc
    12541 ttgtggaaca gcatataatg ctggattact tggtaagtat gccatagaaa aatttgtaaa
    12601 tataccagta ataactgata tagcatcaga atttagatat agcgacccat ttgtagatga
    12661 aaattcatta gtaatattag ttagtcaatc tggtgagaca gcagatactc tagcagtatt
    12721 aagagattca aaggctaaag gagcaagaat actttcaata actaacgttg taggttcatc
    12781 tatagcaaga gaatcagatg atgtattcta tacttgggca ggacctgaag tagcagttgc
    12841 atcaactaag gcatatacta ctcaaataac ttctttatac atgatagctt tagactttgc
    12901 tatcaaaaaa ggaacaataa ctagagaatt ttatgatagt atgatttcta agatgaaaga
    12961 aataccatca aaaatacaag aaatactaga caatgaagaa tatataaaag aagttgctaa
    13021 aacagttgtt agttctgaac atgcattcta tttaggaaga ggtatagact atagcttagc
    13081 aatggaaggt tcattgaaat taaaagagat ttcatatata catgcagaag cttttgcagc
    13141 aggagagcta aagcatggaa caatagcttt aatagaaaaa ggaactcctg taattgccat
    13201 agctactcaa gaaaagttat ttgaaaaaat ggtttctaat atggaagaag taagagcaag
    13261 aggagcttat gtagtagcaa tagctcaaag ccataataag gatgttgaga aagctgctga
    13321 taaaataatc tatataccaa attcagatga tattttatca ccaatattag cagttgtacc
    13381 aatgcaatta cttgcttatc atgtctctgt actaagagga tgcgatgtag ataagccaag
    13441 aaatctagct aaatcagtaa cagttgaata aaaacagatt aaaaattaaa tagataatat
    13501 ttattgaaaa gaactcatcc tgttatttgt attttatagg atgagttttt taaataaata
    13561 ttaaatttgt tttgtttttg ctataataaa ttttataaaa agattgatat taaatcatct
    13621 gtaaaatgat aaatatatag accataccag gtatagggaa cgataaatat agttcatata
    13681 aaatatagtg agtacttaat aaacatatag tcaatatcag ataaaaaaaa taatagctta
    13741 tgagaaaaat taaaatacaa ggtattagta accttgtgat aagataaagt gagtagttta
    13801 aaataagaat ataaggaact atttataaaa gaatataatg aagctaataa agtataagaa
    13861 aattacttta ttttagtaaa ataatttcaa ataaaaattt tttaaattgg gagtataaat
    13921 tatgacaaat gattttaaaa aagaaaagaa agaagattat tttgttaatc ttaaggcaat
    13981 atctactgaa gttttacaag aaaaagtgca agataacgct tgggttatag ttgatactcg
    14041 cttaaatgat gcttataatg gctggaagtt agatggagta aaaagaggtg gacatataaa
    14101 aggagcagta gatttttctg ctaattggtt aagtgtatac tcagatagaa aagatgaagt
    14161 gctagaacaa gcattgaaaa ctaaaagaat tgatttagat aaaaatatag tattatatga
    14221 tgcaaatgga aaagatgctt tggttgtagc agattattta tctaaaaaag gatataaata
    14281 tctatataaa tatgatatta aacaatgggc agacaacgaa aatcttccaa tggaaagata
    14341 taaaaattat caaatgatag ttcctgcttt tataataaaa gatatattag atggaaaaat
    14401 tcctgagaca tttgaagatt caaagaatat aaaaatgatt gaagcgagtt ggggagaaga
    14461 atcgtataca aaagggcata tacctacaag tgttcatgta aataccgata ttatagaacc
    14521 tcctccaaca tggatgcttg ataatgatga taacttaatt aagtttgctt tagactatgg
    14581 attaacaaag gatgatactg taatagtttc aagtagtaca cctatggcat cttatagact
    14641 agctgttata ttgagatata taggagtaaa agatgtaaga gttttgaatg gtggaacaaa
    14701 ctcatggtta tcagcaggat atgaattaga atttactagt aatccaaaac attcatgtac
    14761 taattttgga gcagatatac cagttaactc acaattagtt gttactacct ctgaattaag
    14821 acaaaaacta aaagaaaaaa ataagtttat actagtagat aaccgtactt gggatgaaca
    14881 tataggaaaa gtatctggat atacatatta tgataaaaaa gggcgtatac caggagcttt
    14941 atatggacat tcaggtagtg atagtgtttc actagaagaa tatcgtaata ttgataatac
    15001 aatgagaaat aaatatgaga ttttagaaat gtgggacaag gaaaatatag atgtgaatag
    15061 acagcttata tttatgtgtg gaagtggatg gcgtgctgct gaagtattaa catacgcaaa
    15121 tgtcatagga gtggaaaata cctcccttta tagtgatgga tggatgggct ggagtcttga
    15181 taattcaaat ttaattgaag tgggagaaca caaataaagt ttttgaaagt acgatagagt
    15241 tgtttaaaac aaaggtgttt ttgatttatt gggaagagtg tgtaaattgt gttttgggaa
    15301 gtgtacttag gtatgttcat ttggagctat ggaaattgat aaaaaagtat tatctgttta
    15361 ttttgctggt aaaatgtgaa tagattatag attatagatt atagattata gatttaagta
    15421 tagactaagt aatttatatt acagaagaga atatataaga actagtgcaa gatgtatttg
    15481 atacatataa aaaattggca aatccagaat aaggatagag aaaattgaga ttgaagagtt
    15541 tgaaagagac ttattagatg aaaaatacaa agatgtataa aaatacatat tgagaaagta
    15601 tatctctctt aaatttgtta ataattctat tatacagaaa aacatattta agggggattt
    15661 tttactatga aaagagt
//
LOCUS       DAEPHU010000088        15481 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 01A10CD0081
            SAMN05941466-rid12468953.denovo.088, whole genome shotgun sequence.
ACCESSION   DAEPHU010000088 DAEPHU010000000
VERSION     DAEPHU010000088.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941466
            Sequence Read Archive: SRR6291087
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 15481)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15481)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068158.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 22:43:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,892
            CDSs (total)                      :: 3,805
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 87
            rRNAs                             :: 8, 1, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 55
            CDSs (without protein)            :: 55
            Pseudo Genes (ambiguous residues) :: 0 of 55
            Pseudo Genes (frameshifted)       :: 21 of 55
            Pseudo Genes (incomplete)         :: 28 of 55
            Pseudo Genes (internal stop)      :: 16 of 55
            Pseudo Genes (multiple problems)  :: 8 of 55
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15481
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941466-rid12468953.denovo.088"
                     /strain="01A10CD0081"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            376..942
                     /locus_tag="KR231_003181"
     CDS             376..942
                     /locus_tag="KR231_003181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423380.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbonic anhydrase"
                     /protein_id="HBH0005522.1"
                     /translation="MRKLEEILEYNKSFVENKEYEQYVTSKHPNKKIVVLSCMDTRLT
                     ELLPKAMNLKNGDVKLIKNAGATIMHPFGSIMRSVLVAIYEFDVDEVMVVGHHGCGMC
                     NVDTDKLLGKILDRGISNDVILTLRSAGIDTKQWLHGFDSAEESVKDSIDLIKGHPLI
                     PDGIIVHGLIISPETGKLDVVVNGYEDK"
     gene            1247..1708
                     /locus_tag="KR231_003182"
     CDS             1247..1708
                     /locus_tag="KR231_003182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HBH0005523.1"
                     /translation="MNSNSEEKLNDVFLQLMRIYFIRTHFYFDKLGLYHGQPQILFSL
                     KMKDGQSQKELADKRKVKASTTTVMIKRMEKAGLVERKQDEKDQRVSRIFLTDKGLEI
                     CNKVEEFNKELEREFFLGFSEEEKIVLRRLLMQVRDNLKAGCHKHEDEKYF"
     gene            1776..4022
                     /locus_tag="KR231_003183"
     CDS             1776..4022
                     /locus_tag="KR231_003183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011009877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH0005524.1"
                     /translation="MFKLIKYLKKSALSIVIIVCLLVIQAVCDLSLPEYTSNIVNVGI
                     QQGGVENSVPSVIRESELNKITLFMDKSSKDKVLDNYTLLNKKDYVKYKDKYPGLKDE
                     SLYELNTKDKDTIDDLNVIFGKAILIVSGLEGDSKEVKAMKAQLMSKLPPQATQSGDV
                     DIFKLLSAMPKEQLDTLTKEMSKGFESMPESMITQSSVSYVRSEYEKIGIDTEKTQNN
                     YILFTGAKMLGIAMISMVATITVGFLAARVAASVGRNLRSGVFRKVMSFSNTEMNEFS
                     TASLITRSTNDIQQIQMLMVMLLRIVFYAPIMAIGGVIKVLNTNTSMAWIIAVAVVAI
                     LSLIVVLFSVVMPKFKLVQKLVDKLNLVSREIITGIPVIRAFSTEKHEEERFDKANKN
                     LTKTNLFVNRVMTCMMPAMMLIMNLITVLIVWRGAYSVDSGAMQVGDMMAFIQYTMQI
                     IMSFLMISMVSIMLPRASVSATRIDEVLVSDISIKDPEKSEAQEFKEDKKGLVEFKNV
                     SFMYPDAEEPILTNISFTAKPGETTAFIGSTGSGKSTLINLIPRFFDVTEGEILLGGV
                     NIKNVSQHDLREKIGYVPQKGVLFSGTIESNLKYGRKDATDEEMRTAAEIAQATEFID
                     SKPEAFKTEISQGGTNVSGGQKQRLSIARAIAKNPEVYIFDDSFSALDLKTDAALRKA
                     LKSKTAESTVLIVAQRISTILNAEQIIVLNEGEIVGIGTHKELLKNCEVYEQIALSQL
                     SKEELANE"
     gene            4015..5847
                     /locus_tag="KR231_003184"
     CDS             4015..5847
                     /locus_tag="KR231_003184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH0005525.1"
                     /translation="MSRMGRGPMGKSMGAGQKANDFKGTMRKLIAYLSKFKISIILVI
                     VFAIGSASFSIVGPKILGKATTKIFEGLVSKVSGGNVGIDFNAIGKILTFLLFLYLIS
                     ALFSFIQGFIMSGISQKVSYNLRKEISAKLDRLPMKYFDTKTHGEILSRITNDIDTLN
                     QSLNQSMTQLITSVTTMIGVLIMMLSISGIMTLVAVLILPISMFVISRIIKKSQKYFR
                     YQQEYLGNVNGQVEETYSGQTIVKAFNREDEVIEEFDKLNDSLYNSAWKSQFLSGIMQ
                     PLMMFIGNLGYVMVSILGGWLAIKKTIEVGDIQSFIQYVRNFTQPMTQIAQVANLLQS
                     TAAASERVFEFLEEEEEVQIVENAVSIDGLEGKIDFENVNFGYNPNKTIINDFSVNVE
                     PGQKVAIVGPTGAGKTTIVKLLMRFYDVNSGSILIDGHNIKDFNRSELREMFGMVLQD
                     TWLFSGSIMENIRYGKLNATDEEVIEAAKSAHVHRFIKTLPDGYKMKLNEEASNVSQG
                     QKQLLTIARAILADPKILILDEATSSVDTRTEVLIQKAMDNLMEGRTSFVIAHRLSTI
                     RDADMILVMNEGDIVEQGNHEELLKKGGFYANLYNSQFEEDEAM"
     gene            6566..7843
                     /gene="hflX"
                     /locus_tag="KR231_003185"
     CDS             6566..7843
                     /gene="hflX"
                     /locus_tag="KR231_003185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase HflX"
                     /protein_id="HBH0005526.1"
                     /translation="MDMAKKGITVGLNINNKSEDFNELMIELENLCSACDIDVVGSIT
                     QNAKQVNRAFYIGTGKVEEILNLIKKENIEIVIFYNELSTSQLKNLEEKLNCEIIDRT
                     ALILDIFAQRAKTREAKLQVEVASLKYMLPRLIGSNENLGRQSGGVGTKNRGSGEKKL
                     ELDRRRIEEKITSLNRELDDLKFQRETQRSMRRKSNLPNVALVGYTNAGKSSIMNKLV
                     DIFKNSEEKKVFEKNMLFATLETSVRNIVLANNKEFLLSDTVGFVSNLPHDLVKAFRS
                     TLEEACEADVLLHVIDISNPSYKSHIKVTEDTLKQIGADGIPMIHVYNKIDLIDVDVL
                     DRILDSIDKEGIFVSVKKDINIDKMIKCICDSIFKDYVRCKFLIPYDKGHVVSYFNEN
                     MSIINTEYREDGAILDVECSNIEYNKYKKYALE"
     gene            8076..8573
                     /locus_tag="KR231_003186"
     CDS             8076..8573
                     /locus_tag="KR231_003186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HBH0005527.1"
                     /translation="MDAETLMKKYMVDDDSRKQAIFASIFVMQNKLQTTCDKLDPELT
                     MKQWLLLAIADSVDETLTLTKLGELMGCSRQNVKKLAIALEKKGFIQIEQNEKDSRAI
                     CLVTKDRVQEYSKKVRGMQEKVLQLLFEDFTEKEVEQLFFGIMKLSIGIENVKNYVEN
                     NDVGE"
     gene            8623..9147
                     /locus_tag="KR231_003187"
     CDS             8623..9147
                     /locus_tag="KR231_003187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin"
                     /protein_id="HBH0005528.1"
                     /translation="MKNVVVIYKSKYGSTKKYAKWLSELLSCDIFETKNINIEKVMKY
                     DTIILGGGLYACNIAGISFLKKNYKELQKKNLVVFGVGAAPYDDEVIKKLREVNFKDE
                     LNKIPCFYCRGAWDETKMSFIDYTLCSFFKKSIAKKERQGLKPAEAPLLSGEAFDWCN
                     KENLTPILDYIREL"
     gene            9459..10823
                     /locus_tag="KR231_003188"
     CDS             9459..10823
                     /locus_tag="KR231_003188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldehyde dehydrogenase"
                     /protein_id="HBH0005529.1"
                     /translation="MDIKELVKMQRKYYNTGKTRDISFRIEQLKKLKLVVSQNEEKIL
                     LALKKDLNKSDFEGFMTEVGMFYSELNFAIKNIRKWSKIKRVKSSMVNFPSISKVVPQ
                     PYGVTLIMSPWNYPFQLALIPLVWSLVAGNCVILKPSEYSVSTSSVVKDIVEDTFSKE
                     YVAVVQGSQEESEKLLLERFDYIFFTGSTNVGKIIMKSASEHLTPITLELGGKSPCII
                     LKDANIDLTAKRLTWGKLINAGQTCVAPDYVLVHEDRKNELIEKIKYYTNKYFGDNPC
                     NNEQFPKIINQRHFNRILSLIDKDKIVYGGNYNKETLKIEPTIVDNVNWDDNIMKEEI
                     FGPIFPILTYKDLDEVIQKIIQMPNPLALYIFTKNKYLENKLLEMIPAGGCCINDTVT
                     HIATNYLPFGGIGESGMGSYHGKAGFDTFTHYKSVLKKLNLDVPIRYAPYDNKLIKVL
                     KKIM"
     gene            10962..12128
                     /locus_tag="KR231_003189"
     CDS             10962..12128
                     /locus_tag="KR231_003189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HBH0005530.1"
                     /translation="MKINWNTKYTTIAIYTFIIAASSIIFYLVSSQIDVFSNNLDAIF
                     TTLQPFIIGFAIAYLLNFILKFYEDRIFIKSEKLKKLKQSSKRGLGLLLTYATATLIL
                     YLFMHFVLPQVIESIVGLANDIPMYVNNATKLIDKLMTDLNLDEQYFNLAVDKWNEFV
                     TYIIKFVTDLIPILGSMLKNVASSIWNIVLGLIVSVYLLIDKEKFYGLSKKITYAVFT
                     EKQAARILELTHRSNYTFGRFLGGKILDSFIIGILTFVILTLVKMPYTLLISVIIGIT
                     NIIPFFGPLFGAIPSTLIVMFVSPIKAFWLLLIILIIQQIDGNIIGPKILGDSIGISA
                     FWILFSLLVAGKLLGFIGMVIGVPMFAVIYSIIKDIVESKLDKKGLPTDTSDYM"
     gene            12245..13027
                     /locus_tag="KR231_003190"
     CDS             12245..13027
                     /locus_tag="KR231_003190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="esterase family protein"
                     /protein_id="HBH0005531.1"
                     /translation="MAFIECKFKSKYTGGETDIIVILPVANGKELFSGKEIYDFEGKF
                     KTLYLFHGLEDDQSSWIRYTNVEHYAKNKNIALVIPRVETSFYTDMAYGHQYFTFVSE
                     ELPKFVRAIFPLSDKREDNFVAGMSMGGYGALKLALSKPKEFSAVASFSGSPDMIHEL
                     ENQQIETNADILFHDFGRPEDARNSENDLLYILKNLKERNEDIPKIYQFCGDRDFLYK
                     NNQMFKKYADSLGVDVEYEECVGGHEWRLWNLWIKKFIDIIG"
     gene            complement(13146..13799)
                     /locus_tag="KR231_003191"
     CDS             complement(13146..13799)
                     /locus_tag="KR231_003191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBH0005532.1"
                     /translation="MSKSEKGKETKASIISAARELFFEQGYHKTTTRQIAERANINLG
                     LISYYFSSKSEIGAIIYEDIRNEMQSLIYNYHEEGTMMMFFLAMNADLCFLLKNEAYR
                     NFYLDIAYEEAILSYQRSVTEMVMKRYVNDKESIEHDELILSCIGILAMKPEIIRVYT
                     SHKYDISSQAVIKHFTKQFLINLGHSTDLCEEILEELSKYYIDIVDNFTPIITRVRT"
     gene            complement(13823..15187)
                     /locus_tag="KR231_003192"
     CDS             complement(13823..15187)
                     /locus_tag="KR231_003192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:solute symporter family protein"
                     /protein_id="HBH0005533.1"
                     /translation="MLLLIVTCAIYIWIGFYFSKKVKTASDFLIAGRNLPLPILAATI
                     AATSFGGGCLVGGVQWGAERGLWVGMYSTIGAALACFINAFFAGKLRSLSCDITPADY
                     IETRYGHSVFLRAYQSLVTPISILAIMGSQLISFGSVSTAFGIPYDIAVIIGVIVIII
                     YTYTSGMWGVAVSAFIQLAICIVFLPIVAYISLKLVGDNPLLMLQSMVKEPFFPGNKS
                     ISDFMYTVLPLVLGSIFSYESFLRYQCADNAKNAVKSSVIAGFILLFLAFPIGIIGAI
                     GGSLFPNISSVQVLPQMISTTLPPLISVLFLAAILAAIMSTADSLMTSMSAIISRDIY
                     NKLLHPNIEFNDLKNTLKYSQIASALTAIIGAIIALKFDSLLELLFWPAPLCTGVIFA
                     PFVIGLCWKGATKKGAIYAVIVSVILALLNMIGILTVFDRILVPIIGGSITIFIVSKF
                     SKKD"
BASE COUNT         6045 a         1679 c         2586 g         5171 t
ORIGIN      
        1 tttatatatt gaacaattta tgtaaataga aaatttttca ataagacttt tgagtttaat
       61 cattatattg gtaaggtaaa catttttaaa tctaattata tataggtgaa ataaaaaatt
      121 aattataagt aaggcattta gaataaaatt ttaaaaaaat tataattaaa aaaataatga
      181 aaatatataa tattagttta gattataaaa aataaatata caaatactta taaatacaag
      241 ttatatacaa gatttatagt agagtaataa tcttataaaa taatttaata aatataaatt
      301 aaattatatg tgtatatatt gtactttaat agtgatataa taataaaaaa atttttaaag
      361 agggtgatat tacatatgag aaaacttgaa gagatattag aatataataa atcatttgta
      421 gagaacaaag aatatgaaca atatgtgaca tcaaaacatc caaataaaaa aatagtagtc
      481 ttatcttgta tggatacaag attaactgag cttttgccta aggctatgaa tttgaaaaat
      541 ggagatgtga aactaataaa aaatgcagga gctactataa tgcatccttt tggaagtatt
      601 atgagaagtg ttttagttgc aatttacgaa tttgatgtag atgaggttat ggttgtaggg
      661 catcatggat gtggtatgtg taatgttgat acggataagt tacttggtaa aattttagat
      721 agaggaatat ctaatgatgt aatacttaca cttcgtagtg ctggaattga tacaaaacaa
      781 tggttacatg gattcgattc tgcagaagaa tctgtaaaag atagtattga tttaataaaa
      841 gggcatcctt taattccaga tggtattatt gtacatggtc taattatatc acctgaaact
      901 gggaagttag atgttgttgt aaatggatat gaagataagt agagtatcat aatgttatat
      961 aatcaagata ctgttgaata agatgttgtt tcaaaattta ttttgggaca acttttttat
     1021 ttgaaaatat atgaaaaggt ttattttaag ctttacaata aaaaatataa gtagctgact
     1081 aattaaaaat cttactatta tttattaaaa ttataactat atgatataaa aatatttaat
     1141 aaatgaaatt tatatgaatt ttttataaat atattgaaaa aatgcatgca gtatagtaaa
     1201 ataatgctta gccgactaag taatataaaa aataaggagg gcaagtatga atagcaattc
     1261 tgaagaaaaa ttaaatgatg ttttcttgca attaatgcga atatatttta taagaactca
     1321 tttttatttt gataaattag gcttatatca tggtcaaccc caaatacttt tttctttaaa
     1381 gatgaaagat gggcaaagtc aaaaagaatt agcagataaa aggaaagtaa aagcatctac
     1441 aactacagtt atgataaaga ggatggaaaa agctggactt gtggaaagaa aacaagatga
     1501 aaaggaccaa agagtatcta ggattttttt gacagacaaa ggtttagaaa tatgtaataa
     1561 agttgaagaa tttaacaagg aattggaaag agagtttttt ttaggattta gtgaagaaga
     1621 aaaaatagta cttagaagac ttctaatgca agtacgagat aatttaaaag caggatgtca
     1681 taagcatgaa gatgaaaaat atttttaaag tttaaaataa tgtttttcaa tttaatgtta
     1741 ttagactaat taatattaca gaagggaaga aatgtatgtt taaattaatt aaatatttaa
     1801 agaaatcggc attatcaata gtaataatag tctgtctatt ggtaattcaa gcggtatgtg
     1861 acctttcttt accagaatac acatccaata tagtaaatgt aggtatacaa caaggtggag
     1921 tagaaaactc tgttccatct gtgattagag agagtgaatt aaataaaatt actttattta
     1981 tggataaaag tagtaaggat aaagtactag ataattatac tttgctgaat aaaaaggatt
     2041 atgttaagta taaagataag tacccaggtc taaaagatga atctctttat gagttaaata
     2101 ctaaagacaa agacactata gatgatttaa atgttatttt tggtaaagct attttaatag
     2161 tatcagggct tgagggcgat agtaaagagg taaaagctat gaaagctcag ttaatgagta
     2221 aacttccacc acaagctact caaagtggag atgttgatat atttaaattg ttatcagcaa
     2281 tgccaaagga acagttagat acattgacta aagagatgag caaaggcttt gaaagtatgc
     2341 cagagagtat gataacacaa agctctgttt catatgtaag gtcagaatat gagaaaatag
     2401 gtattgatac agaaaaaact caaaataatt atatattatt tactggtgct aaaatgcttg
     2461 gtatagcaat gattagtatg gtagctacaa taacagtagg atttttagca gcaagagtag
     2521 ccgcaagtgt aggtagaaat ttaagaagtg gagtatttag aaaagttatg tcattttcaa
     2581 atactgaaat gaatgaattt tctacagctt cattaattac tcgtagtaca aatgatattc
     2641 aacagataca aatgttgatg gttatgttgc ttagaatagt attctatgca cctataatgg
     2701 ctataggtgg agtgataaag gttttaaaca caaatacttc aatggcctgg attatagcag
     2761 tagcagtagt tgctatctta tcattaattg tagtgttatt ctcagtggtt atgcctaagt
     2821 ttaaactggt tcaaaagctt gttgataagt taaacttagt aagccgtgaa ataattactg
     2881 gtattccagt tatcagagct tttagtactg aaaaacatga agaagaaaga tttgataaag
     2941 caaataaaaa tttaactaaa acaaatcttt ttgtaaatag agttatgaca tgtatgatgc
     3001 ctgctatgat gcttataatg aaccttatca cagttcttat agtttggaga ggtgcataca
     3061 gtgttgattc tggagcaatg caagttggag atatgatggc atttatacaa tatacaatgc
     3121 aaataataat gtcattctta atgatatcaa tggtatctat tatgcttcca agagcatccg
     3181 tttcagctac acgtatagat gaagtattag tgtcagatat aagcataaaa gacccagaaa
     3241 aatcagaggc acaagagttt aaggaagata aaaagggtct tgttgaattt aaaaatgttt
     3301 cgttcatgta tccagacgca gaagaaccta tattaacaaa tatatctttt acagcaaagc
     3361 caggagaaac aactgccttt ataggaagta ctggtagtgg taagtcaact cttataaatt
     3421 taattcctcg tttctttgat gttactgaag gagaaatatt acttggtgga gttaatataa
     3481 aaaatgtttc tcaacatgat ttaagggaaa aaattggata tgtacctcaa aagggagtat
     3541 tgttttctgg tactatagaa tccaacttaa aatatggtag aaaagacgca acagatgaag
     3601 aaatgagaac agcagctgaa atagctcaag ctacagaatt tatagattct aaaccggaag
     3661 cttttaaaac tgaaatttct caaggtggaa caaatgtatc tggaggtcaa aaacaaagac
     3721 tttctattgc aagagcaata gcaaaaaatc cagaagttta tatatttgat gatagttttt
     3781 cagcacttga cttaaaaact gatgcagctc ttcgtaaggc tttaaaatca aaaactgctg
     3841 aaagtacagt tctaatagtt gcacaaagaa ttagtactat cttaaatgca gaacagataa
     3901 ttgttttaaa tgagggcgaa atagttggaa taggaacaca taaagagctt ctaaaaaatt
     3961 gcgaagttta tgagcaaata gctttatcac aactttcaaa ggaggagcta gctaatgagt
     4021 agaatgggaa gaggtcctat gggaaaatct atgggagcag gacaaaaagc aaatgacttt
     4081 aaagggacta tgcgaaaact aattgcatat ttatctaaat ttaaaatatc aataattcta
     4141 gtaattgtat ttgctattgg tagtgcgtcg ttttctatag taggtccaaa aattttagga
     4201 aaggcaacta caaagatatt tgaagggcta gtgagtaaag tttctggagg aaacgtaggt
     4261 atagatttta atgcaattgg aaaaatctta acctttttac ttttccttta tttgataagt
     4321 gcactgttct cttttataca aggatttata atgagtggaa tttctcaaaa agtatcctat
     4381 aatttaagaa aagagatttc agcaaaattg gatagattgc caatgaagta ttttgatact
     4441 aagacgcatg gtgaaatatt atcgagaatt acgaatgata tagatacttt aaatcaaagt
     4501 ttaaatcaaa gtatgacaca gcttataaca tcagtaacaa ctatgatagg tgttttgata
     4561 atgatgttat ctataagtgg aattatgaca ttagtggcag ttttaatatt accaatatca
     4621 atgtttgtaa tttcaagaat aataaagaaa tcacaaaaat actttagata tcaacaagaa
     4681 tatttaggaa atgtaaatgg tcaagttgag gaaacttaca gtggccaaac aatagtaaaa
     4741 gcatttaatc gtgaggatga agtaattgaa gagtttgata aactaaatga tagcctgtat
     4801 aattcagcgt ggaaatctca atttttatca ggtataatgc aaccacttat gatgtttatt
     4861 ggaaacttgg gatatgtaat ggtatcaatc ttaggaggtt ggcttgcaat taagaaaaca
     4921 attgaggttg gtgacataca gtcatttata caatatgtaa gaaactttac acagccaatg
     4981 actcagattg cacaggttgc caatttattg caatcaacag cagcagcttc tgaaagagta
     5041 tttgagtttt tagaagagga agaagaagtc caaattgttg aaaatgcagt ttcaatagat
     5101 ggtttagaag gtaaaattga ttttgaaaat gtcaactttg gatataaccc aaacaagact
     5161 ataataaatg atttctcagt aaatgttgaa cctggtcaaa aagttgctat tgttggacct
     5221 acaggagcag gtaaaactac aatagttaaa ctgttaatga gattttatga tgttaatagc
     5281 ggttcaatac tgattgatgg tcataatatt aaagatttta atcgtagtga gcttagagaa
     5341 atgtttggta tggttcttca agatacatgg ttatttagtg gttcaattat ggaaaatata
     5401 agatatggta agttgaatgc tacagatgaa gaagttatag aggctgctaa atctgcacat
     5461 gttcatagat ttattaagac attaccagat ggatataaga tgaaattaaa tgaagaagca
     5521 agtaatgttt ctcaaggtca aaaacaatta ttgactatag ctcgtgctat tttagctgat
     5581 cctaaaattt taatattaga tgaagctaca agttctgtcg atactagaac agaagtattg
     5641 attcaaaaag ctatggataa tcttatggaa ggtagaacaa gttttgttat agcccacaga
     5701 ttatcaacta tacgtgatgc tgatatgatt cttgtaatga atgaaggaga tatagttgaa
     5761 caaggaaatc atgaggaact tctaaagaaa ggcggattct atgccaatct ttacaattct
     5821 caatttgaag aagatgaagc aatgtaacaa aaaactatct tagcatagac atgtaattaa
     5881 taagataaaa taaatgaggg tgccttaaaa tgaacttttt aattcataag gcactctttt
     5941 gtgtatgaaa taaagtgtat ttttatcatt ttaacaatga aaaagaggat tctctatatt
     6001 ttgagatagc cacataattt tatgtcttta caaagtgttt attttattat aatatgtagt
     6061 aaggaaaatg ttggaggtga ttatcaaaat gtatatttaa ttttattctt taaattttat
     6121 tataaataga atttaatttt aatagttgat gattatattg aagtatatgt ttttattact
     6181 tttattaatc atgcaaataa ctacttaaat ttaagaatag ggttaaatat aaaatgataa
     6241 ttacatataa gttaattaaa ctaatgtatt tttaatatat atttagaatt ttaatccttc
     6301 ttatgatata agtagcttgt tttgtattac ttagatttgt aaggagtttt tttattgaaa
     6361 aaactgcata atatatttgg gaggaggtgt aagaaagtga ttttttatat aagattgaga
     6421 aaataatgca cgattatggt tattataata gtaaataaga agtgtcattt aaggataaga
     6481 taaaaagcaa aattcttgat gaatttaatt atagagccat aatctcgtgc tatagattaa
     6541 ataaaaaata gcagataagg agaatatgga tatggcgaaa aaaggaataa cagtaggatt
     6601 aaacataaat aataaatctg aggactttaa tgaactaatg attgaacttg aaaacttatg
     6661 ttcagcatgt gatattgatg ttgtagggag tataactcaa aatgcaaagc aggttaatag
     6721 agcattttac attgggacag gtaaagttga ggaaatatta aacttaataa agaaagaaaa
     6781 tatagagata gttatatttt acaatgaact ttctacatca caactaaaaa atcttgaaga
     6841 aaagcttaat tgtgaaatta tagatagaac ggcattgata cttgatatat ttgcacaaag
     6901 ggcaaaaact agagaagcta aacttcaagt agaagtagca agtttaaaat atatgttacc
     6961 aagacttata ggttcaaatg aaaatttagg acgtcaaagt ggtggagttg gtactaaaaa
     7021 tagaggttct ggtgagaaaa aattagaact tgaccgtaga agaatagaag aaaagataac
     7081 atctttaaat agggagttgg atgatttaaa attccaaaga gaaactcaaa gaagtatgag
     7141 aagaaaatca aatcttccaa atgtagctct agtcgggtat acaaatgctg gtaaatcttc
     7201 aataatgaat aaactagtag atatatttaa aaactctgaa gaaaagaaag tgtttgagaa
     7261 aaacatgtta tttgctacac ttgaaacttc tgtcagaaat atagttcttg caaataacaa
     7321 agaattttta ttatctgata ctgttggttt tgtaagtaat ctaccacatg acttagtaaa
     7381 agcatttagg tcaacattag aagaagcatg tgaggcagac gtactgttac atgttattga
     7441 tatttcaaat ccaagctata aaagtcatat taaagtgaca gaagatactt taaaacaaat
     7501 aggtgcagat ggtataccta tgatacatgt gtataataaa attgatttaa tagatgtaga
     7561 cgtattggat agaattttag atagtattga taaagaaggt atatttgttt cagttaaaaa
     7621 agatataaat atagataaaa tgataaaatg tatttgtgat agcatattta aagattatgt
     7681 aagatgtaag ttcttaattc catatgataa aggtcatgta gtttcttatt ttaacgaaaa
     7741 tatgagcatt ataaatacag aatacagaga agatggagct attttagatg tagaatgtag
     7801 caatatagaa tataataagt ataaaaagta tgctttagag taaattttga aaaacttatt
     7861 atagcctaaa atatatttaa tttataattt attataaatt gattgtaaat atgattttat
     7921 gaaacggtat agccataatg ctatgccgtt ttgccattta taataaaaat aaatttattg
     7981 acataatagt aactaattac tataatataa agtaattagt tactatttaa aattatcaaa
     8041 aaattaaaat ctaagataaa gagaagtgta taataatgga tgcagaaact ttaatgaaaa
     8101 aatatatggt agatgatgat agtagaaaac aagctatatt tgcaagtata tttgtaatgc
     8161 aaaataaact tcaaactaca tgtgataaat tagacccaga attaacaatg aaacaatggt
     8221 tacttttagc tattgcggac tctgtagatg aaactcttac attaaccaaa cttggagaat
     8281 taatggggtg ctcaagacaa aatgtaaaaa aactagctat tgctttagaa aagaaaggtt
     8341 ttatacaaat tgagcagaat gaaaaagatt caagagctat ctgtcttgtg acaaaagata
     8401 gagtgcaaga gtattctaaa aaagtaagag gtatgcagga aaaagtatta cagcttttat
     8461 ttgaagattt tacagagaaa gaagtggaac agttattttt tggaattatg aaattaagta
     8521 taggaattga aaatgtgaaa aattatgtag aaaataatga cgttggagaa taagcaagta
     8581 tcaaatcaac tttgtatgac atcagagagg gggataattt atatgaaaaa tgtagtagtg
     8641 atttataaga gtaagtatgg ttcaacaaaa aaatatgcta aatggctttc agaattattg
     8701 tcttgtgata tttttgaaac taagaatatt aatatagaaa aggttatgaa gtatgatacg
     8761 attattttag gaggaggtct ttatgcttgt aatatagcgg gaatttcttt cttaaaaaaa
     8821 aattataaag aattgcagaa aaaaaattta gtagtatttg gcgtaggagc tgctccatat
     8881 gatgatgaag taataaagaa attaagagaa gtaaatttta aggatgaatt aaacaaaatt
     8941 ccttgctttt attgtcgtgg ggcatgggat gagacaaaaa tgtcttttat agattatact
     9001 ctttgtagtt tttttaaaaa atctatagct aaaaaagaac gtcaaggtct taaaccagca
     9061 gaagcacctt tattgtctgg agaagcattt gattggtgta ataaagaaaa tttaactcca
     9121 atacttgatt atataagaga actttaagag gtatatattt ataattattt attatctaaa
     9181 gttagatttc atagaaactt actagacatt atttataaaa taatattatt aaagatggat
     9241 aatttaattg attcaataag gttataattt taaaaaatgt ttattttaaa ataaattatt
     9301 ttataagctt acttatactt aataaggggc tttttttatt ggaagattta tgttatattg
     9361 agatgaattt attatgatat aaaaaataat gttaggataa atttaaatct ttttctaaaa
     9421 atgtattaat ataattctta aagaaaggat ttttaataat ggatataaaa gagttagtta
     9481 aaatgcaaag aaaatattat aatacaggta aaacaagaga tatatcgttt cgtatagaac
     9541 agttgaagaa acttaagtta gttgtatcac aaaatgaaga aaaaatactt ttagcactaa
     9601 agaaagattt aaataaatcg gattttgaag gttttatgac agaagtaggc atgttttata
     9661 gtgaattaaa ctttgctata aagaatataa gaaaatggag caaaataaaa agagttaaat
     9721 caagtatggt taattttcca tctatatcca aagttgttcc acaaccttat ggtgttactc
     9781 tcataatgtc accttggaat tatccatttc aattagcact tataccatta gtttggtcat
     9841 tagtagcagg gaattgtgtt atattaaaac cttctgaata ttctgtgtca acatctagtg
     9901 tagttaaaga catagtggaa gatacttttt caaaagaata tgttgcagtt gttcaaggaa
     9961 gtcaagaaga aagtgaaaag ttactattgg aaagatttga ttatatattt tttacaggaa
    10021 gtactaatgt tggtaaaata atcatgaaat cagcatcaga gcatttaact cctattactt
    10081 tagaacttgg aggaaaaagt ccttgtatca ttttaaaaga tgctaatata gaccttactg
    10141 ccaaaagact tacttgggga aaactaataa atgcaggaca aacctgcgtg gctccagatt
    10201 atgttttagt gcatgaagat agaaaaaatg agttaataga gaaaataaaa tattatacta
    10261 ataagtattt tggagataat ccatgtaata atgagcaatt tcctaaaatc ataaatcaga
    10321 gacattttaa tcggatatta tctcttattg ataaagataa gatagtctat ggtggaaatt
    10381 ataataagga gacattaaag atagagccaa ctatagtaga caatgttaat tgggatgata
    10441 atataatgaa ggaagaaata tttgggccta tatttcccat tttaacatat aaagatttag
    10501 atgaagtaat acaaaaaatt atacaaatgc caaatccatt ggcactttat atttttacaa
    10561 aaaataagta cctagaaaat aaacttttag aaatgattcc agcaggcgga tgttgtatca
    10621 atgatacagt tactcatata gctacgaatt acttaccttt tggtggtatt ggtgaaagtg
    10681 gtatgggctc atatcatgga aaagctggat tcgatacatt tactcactat aagagtgtgt
    10741 taaaaaaatt aaatttggat gtccctatta gatatgctcc atacgataat aaattaatta
    10801 aggttcttaa aaagataatg taggttatat tgtagaataa taaatataaa taaaattgag
    10861 tatttgtatt ctgaatatat tttattttta atttggtata tttgttataa aagtggtgat
    10921 tttgtgataa aatttaatta tatagaaata aggaggaaaa aatgaaaatt aattggaata
    10981 caaaatacac aacaatagca atttatacat ttataatagc tgctagtagt attatatttt
    11041 atctagtatc atcacaaatt gatgtatttt ctaataattt agatgctata tttacaacat
    11101 tacaaccttt tataatagga tttgctattg catatcttct taattttatt ttaaagtttt
    11161 atgaagacag aatttttata aaaagtgaga aattaaaaaa actaaaacaa agttcaaaaa
    11221 gaggcttggg tcttttatta acatatgcaa cagctacatt gatactttac ttatttatgc
    11281 atttcgtatt gccacaagta attgagagta ttgttggact agcaaatgat atacctatgt
    11341 atgtaaacaa tgcaactaag cttattgata aattaatgac tgatttaaat cttgatgagc
    11401 aatactttaa tttggcagtt gataagtgga atgagtttgt tacatatatt ataaagtttg
    11461 taacagattt aatcccaata ttaggaagta tgttaaagaa tgtagcctct agtatatgga
    11521 atattgtact aggattaatt gtttcagtat acttattaat tgataaagaa aaattctatg
    11581 gattaagcaa aaaaataact tatgcagtat ttacagaaaa acaagctgcc agaattttag
    11641 aattaactca tagaagtaac tatacatttg gaagattttt aggtggcaaa atattagatt
    11701 cattcattat aggtattcta acatttgtaa tacttacgtt agttaaaatg ccatatacat
    11761 tattaatatc agttataatt ggtattacaa atattatccc tttctttgga cctttatttg
    11821 gagctatacc atctacgcta atagtgatgt ttgtatctcc tataaaagct ttctggttat
    11881 tgttgattat attaataata caacagatag atggaaatat tataggacct aaaatacttg
    11941 gagattcaat tggtatatct gcattttgga ttttgttctc cttattggtt gcaggaaaat
    12001 tattaggttt tattggaatg gttataggag ttccaatgtt tgcagtaatt tattctataa
    12061 ttaaggatat tgttgaaagt aaattggata aaaagggatt accgacagat acttccgatt
    12121 atatgtagct aaaaaatatt atgtataatt aaaaatatat aaattaagca atatttaaag
    12181 cactgagaaa gttaaactct tggtgctttt tagatataaa attattatag aagaggtgtt
    12241 ttttgtggca tttatagaat gtaaatttaa atctaaatat actggaggag aaactgatat
    12301 aattgtaatt ttgcctgtag caaatggaaa agaacttttt agtggtaaag agatatatga
    12361 ttttgaaggt aaatttaaaa cattatactt atttcatggt ttagaagatg accaaagctc
    12421 atggattaga tatactaatg tagagcatta tgctaaaaat aaaaatatag ccctagtaat
    12481 accaagagta gaaactagtt tttataccga tatggcgtat ggacaccaat attttacttt
    12541 tgtaagcgag gaattaccta aatttgttag agctatattt cctttatcag ataaaaggga
    12601 agataacttt gtagctggta tgtctatggg gggatatgga gctttaaaat tagcgctttc
    12661 aaaaccaaaa gagttttcgg cagttgcaag tttttctggt tcgcctgata tgattcatga
    12721 gttagaaaat caacaaatag aaaccaatgc agacattcta tttcacgatt ttggtagacc
    12781 agaagacgct agaaatagtg agaatgattt actttacata cttaagaacc ttaaagaaag
    12841 aaatgaagat attcctaaaa tttatcaatt ttgtggtgat agagattttt tatataaaaa
    12901 taatcagatg tttaaaaaat atgcagattc tctgggtgta gatgttgaat atgaagagtg
    12961 tgtagggggg catgaatggc gtctttggaa tttatggata aagaaattta tagatataat
    13021 tggatagtac acttatggta ttaacaggta tactataaaa tatctttaaa tatgataaag
    13081 actgaaatcc taaaatcaaa ttatgatttt aaaatttcag tctctaagaa tttaataaaa
    13141 ttttattaag ttcttacacg agttattatt ggagtaaaat tgtcaactat atctatatag
    13201 tatttactca attcctctaa aatctcttcg cataaatccg tactatgacc aagattaata
    13261 agaaactgtt ttgtaaaatg ctttattaca gcttgagaag atatatcgta cttgtgtgaa
    13321 gtataaactc taattatttc aggtttcata gcaagtatac caatacaaga aagtattaat
    13381 tcatcatgtt ctatagattc tttatcatta acatatcttt tcatgaccat ttcggttaca
    13441 cttctttgat agcttaaaat agcttcttca taagctatat ccaaataaaa atttctatat
    13501 gcttcgtttt ttagaaggaa acaaaggtca gcattcatag caagaaagaa catcatcata
    13561 gtaccttctt catggtagtt atagattaaa gactgcattt catttcttat atcttcatat
    13621 attatagctc ctatttcgct tttacttgag aagtaatagc ttattagacc taaatttata
    13681 ttagctcttt ctgcaatttg cctagttgtt gtcttatgat aaccttgctc aaaaaataat
    13741 tctctagcag cacttataat actagctttt gtttctttgc ccttttctga ttttgacata
    13801 tttactgtgt atacctctct tttcaatctt tttttgaaaa tttgctaact ataaatattg
    13861 taatagaacc acctattata ggaaccaaaa ttctgtcaaa tacagtaaga ataccaatca
    13921 tatttaataa tgccaatata acacttacta taacagcata gatagctcct ttttttgtag
    13981 cacctttcca gcaaagacca attacaaatg gtgcaaatat tacacctgta cataatggag
    14041 ctggccaaaa caataattct aataaactat caaatttaag tgctatgatt gcacctatta
    14101 tagctgtcaa agctgatgca atttgagaat actttagagt attttttaaa tcattaaatt
    14161 ctatattagg atgtaataat ttgttataaa tatctcttga tataatagca ctcattgagg
    14221 tcattaatga atcggcagta gacattatgg cagccaatat agcagctaag aataatacag
    14281 atattaaagg tggcaaagta gtcgatatca tttgaggtaa aacctgaaca gatgatatat
    14341 ttggaaataa actaccacca atagctccaa ttattcctat agggaaagca agaaataata
    14401 gtataaatcc tgcaattaca ctacttttaa ctgcattttt agcattatca gcacattgat
    14461 atcttaaaaa actttcataa gaaaatattg agcctaaaac taatggtaaa actgtataca
    14521 taaaatcact aatcgattta tttcctggaa agaatggttc ttttaccatt gattgtaaca
    14581 taagtaaagg gttgtcgcca actaatttta agcttatata agctactatt ggcaaaaaca
    14641 ctatacaaat agcaagttga ataaatgctg atactgcaac tccccacatt cctgatgtat
    14701 aagtatatat aatgataact ataactccta taattacagc tatatcataa ggaataccaa
    14761 atgcagtaga tacagaacca aaagaaatca attgactacc cataatagct agtatagata
    14821 ttggtgttac aagactttga taagctctta aaaatacact atgaccatat ctagtttcaa
    14881 tataatcagc aggtgttata tcacaagata agcttcttaa ttttcctgcg aaaaatgcat
    14941 ttataaagca agctaaagct gcacctatag tagaatacat tccaacccaa agtcctcttt
    15001 cagctcccca ttgaactcca ccaactaagc accctcctcc aaaagatgta gcagcaatgg
    15061 ttgcagctag tataggcaaa ggcagatttc tacctgcgat taggaaatcg gatgctgttt
    15121 taactttttt tgaaaaataa aaaccaatcc atatgtatat tgcacacgta acaattaaaa
    15181 gtaacatagt cttttctcct ttataaaata ttttaataaa atatacaaaa tatatttaaa
    15241 atatatttta tataaaagta gtacgatatt tgttttattg gttttagatt aatatagcta
    15301 taataattta tgatattaga tggaaattac gtaaaaatag aaaattgaaa attctgaaat
    15361 ttttgtatat tgatatttat ctcatagatt cttttttgta attgtaacac gcttttattt
    15421 ttaaatcaat agtacatgta taaaaataaa aggaatttaa ataagaaaaa gatattttta
    15481 a
//
LOCUS       DAEPHU010000089        15432 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 01A10CD0081
            SAMN05941466-rid12468953.denovo.089, whole genome shotgun sequence.
ACCESSION   DAEPHU010000089 DAEPHU010000000
VERSION     DAEPHU010000089.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941466
            Sequence Read Archive: SRR6291087
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 15432)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15432)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068158.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 22:43:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,892
            CDSs (total)                      :: 3,805
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 87
            rRNAs                             :: 8, 1, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 55
            CDSs (without protein)            :: 55
            Pseudo Genes (ambiguous residues) :: 0 of 55
            Pseudo Genes (frameshifted)       :: 21 of 55
            Pseudo Genes (incomplete)         :: 28 of 55
            Pseudo Genes (internal stop)      :: 16 of 55
            Pseudo Genes (multiple problems)  :: 8 of 55
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15432
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941466-rid12468953.denovo.089"
                     /strain="01A10CD0081"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            325..3228
                     /locus_tag="KR231_003193"
     CDS             325..3228
                     /locus_tag="KR231_003193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HBH0005534.1"
                     /translation="MELRDKLVNIINTENKKDPLTDVQIAKFLSTTRENITNLRKELN
                     ISNSRQRRYPYLKSAISAILQKNKNISVSEITRELMTEGFNISRRVVEELLPKESLEM
                     DVVEESEEESNDPFETLIGNKGSLRNAVEQAKSAILYPPKGLPTLIIGESGVGKSLFS
                     RHMYEFAKQKKIVKESSNFVVFNCADYSDNPQLLLSLLFGYKKGAFTGAEYDTPGLVE
                     EADEGVLFLDEIHRLPPKGQEILFSILDRGKFRRLGETNAERKVSIMLIGATTENVET
                     NLLLTFRRRIPMLITLPPLHDRLLKEKIDLIYNIFQQECNRINAKIFVDKNVIEILAL
                     KKFSGNIGQLQNMIQVLCARAFMKFINSKDEDSESIVVVDINEVLKLKDSFKDAAFQE
                     IEYTEIRKYLKNAIFIPFNLEESSVKGSLLSDEYILPEDIYKTIEKKYYDLKSLDIED
                     IDIENILWTFILNRFADLKFNLDSNEEIFSMSDLNSFVSDSLVKLVKELMNDIVEKNM
                     NLEVNKNMFKYLAIHLEEAIKRIKLNQKIINVNLEKIKIDFSKEYEISKSFAIKIEES
                     IGIKIPDDEIGFITLYIKSALKNEVKKDKVGLIIISHGRIATETVNVVKELLGVKFPV
                     AIDMPLDEKPINIYNKAVELSKIIDQGKGILFLVDIGSLTNIGQIVNKRTNISTKTID
                     RVDLLMALEATRKVSMGEEELDEIFFSLLKDRMGYNYELEKHIDKSNAIVTLCLTGEG
                     TAKYISKTLEEKYDNTKCYQMSALDENLFCKIENLKETNNILAIVGTINPKIPGINFI
                     PYNKELFKNLDIYLSKSKQQDDRPVKSYERMLDEDLVIFEPDIYFKKDLLEYVCSILI
                     NKEYVEKDYLDSVLHREEMLPTYSKGAIGVPHGDSSTVNSTRFVFVKLKNPIDWGVGN
                     VNFIFMPVFQANDKEIVKNVLEILKDAEFMNNANKCFDKDAFRRIIFDKFKHL"
     gene            3261..3707
                     /locus_tag="KR231_003194"
     CDS             3261..3707
                     /locus_tag="KR231_003194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBH0005535.1"
                     /translation="MNVDLISLGLESNDYESVIEELGSIMCKKEYVKETYINAVLERE
                     RTLPTGLDIGEMCVAIPHTDSKHVNESNVAVGILKNPVKFNSMIDPKDRLDVELVFLL
                     AVKNPDSQVKLLKDLMSVFQNIKLLKNIKNASTKEEVAKLLDFIEI"
     gene            3830..4132
                     /locus_tag="KR231_003195"
     CDS             3830..4132
                     /locus_tag="KR231_003195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBH0005536.1"
                     /translation="MKQFNVLSVCGSGTVTSSMVAGKLKEVLGNKGISITTTEARPTE
                     ALNLAQSGRFDFITFTSPLQTGDYGIPTINAFACLTGIGEEAFFEEVLTVIEGIDK"
     gene            4313..5719
                     /locus_tag="KR231_003196"
     CDS             4313..5719
                     /locus_tag="KR231_003196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS galactitol transporter subunit IIC"
                     /protein_id="HBH0005537.1"
                     /translation="MLEFMKSIIDTFGSAIIVPIIIFIIAKIFKVTTKKSFLSAVYAG
                     VALQGFTLILNSFTPIITPVINRMVESTGVNLPVFDVGWQATSLVAFSTSAGMIYLGL
                     GILLQTILFLIKWTDVFQPSDLWNNYSYMVWGAMVIGVTGNFPLGIACMVLLNLYSLL
                     ISELVAKRWSSYYRYPNCTIIAMHNVEASVFAVFADPIYNKLGLNKIKLNPKELEKKL
                     GFLGEPITLGLFLGMFIGILGNMTRINTMEAWGEIMKVGISTSAVMAIFPKVASMFAQ
                     AFAPITEAARKIMQKAGNREWYIAVNDAVGYGEPATLISGLILIPIMLVIAMVLPGNK
                     VLPVVDLLAIPYMVQGLVAIHNGNIPKVLVSGIIWFGLGLYVCTSTAPLFTDMATNIG
                     VAIPAGAMLITSFNILGKPLMGLVFFAFLSANPIYIGLSVVIYFVLWALFRKNKTSIL
                     DYLEKQALKNVEEEPVAV"
     gene            6063..7121
                     /locus_tag="KR231_003197"
     CDS             6063..7121
                     /locus_tag="KR231_003197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012101107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactitol-1-phosphate 5-dehydrogenase"
                     /protein_id="HBH0005538.1"
                     /translation="MGDKMRASVLYSVGDVRYEMVDIPEITDTQVLVNVKYVGICGSD
                     LPRSMVSGLSGNTKYPLILGHEFSGEVVKIGEKVKHINVGDRVAVAPLVPCGKCDYCN
                     EGNFGLCDDYNIIGTRVNGAFAEYVRVPEEHILKLPDTLDYETAAGIEPATIAYHGIS
                     KSNIRVGDSVVVLGCGPIGQFVIQWAKVFGASKIIAVDIFDEKLELSKLLGANYILNS
                     KEVNVIKEIKKITNGGADVVIETAGSRFTQEQSLFVAKKRGNIVFVGISHTELPLSAD
                     ATECILRGELTLKGSWNSYTSPYPGRAWTATLDFMGKGDIIFKPMISHKIGLNEVGDF
                     LSKMSKREINFNKILVEI"
     gene            7220..7906
                     /gene="araD"
                     /locus_tag="KR231_003198"
     CDS             7220..7906
                     /gene="araD"
                     /locus_tag="KR231_003198"
                     /EC_number="5.1.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 4-epimerase"
                     /protein_id="HBH0005539.1"
                     /translation="MLENLKEEVLKANLELPKKKLITYTWGNVSGIDREKGLVVIKPS
                     GVEYSNMTVEDMVVVDLEGNIVDGKLRPSSDTPTHLVLYKEFEELGGIVHTHSSWATI
                     WAQIGKSIPSCGTTHADYFYGSIPCTRKMTREEICNEYEKETGNVIIEEFMGRNPIHC
                     PGIIVNDHGPFTWGKDANEAVHNAVVLEEVAKMAYYTELMSPDNIMDKVLMNKHFSRK
                     HGKNAYYGQK"
     gene            7924..8571
                     /locus_tag="KR231_003199"
     CDS             7924..8571
                     /locus_tag="KR231_003199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class II aldolase/adducin family protein"
                     /protein_id="HBH0005540.1"
                     /translation="MLDSLKGKIVEIAIKAEHYGLCKEKTGNFSIRDKDTGYILITPS
                     GVGREELKVEHICVLDLDGNVIEVEKGIKPSSEVLMHIEIYKTRENINAISHTHSLYA
                     TAFSVAKKPIIPIVYESVNYGGYVDIAPYERPGTLKLAKSVSKLLIDTDACLLERHGL
                     TTVGNDLDEALLKSRYVEEVAEIYYRSLVLNQFKELEVVDVDEFKSWKYPEEIKF"
     gene            complement(8744..10111)
                     /locus_tag="KR231_003200"
     CDS             complement(8744..10111)
                     /locus_tag="KR231_003200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:alanine symporter family protein"
                     /protein_id="HBH0005541.1"
                     /translation="MNLIDILNKVDAFIWGPPLLVLLVGTGILLTVKLGVVQITKLPR
                     ALKLIFSAENKGSGDVSSFAALCTALAATVGTGNIVGVATAIKAGGPGALFWMWIAAF
                     FGMATKYSEGVLAIKYRTKDKNGQVSGGPMYYIVNGMGEKWRPLAIFFAISGILVALL
                     GIGTFTQVNSITDAINNSFGIDPRITGVVLAVFVALVVFGGLKSISNVATKIVPFMAV
                     IYVVICGIILISFWNKIPETFMLIIKSAFTPTAATGGFLGATMSLAIRNGIARGVFSN
                     ESGLGSAPIAAAAAKTEWPAEQGLISMTGTFIDTIIICTLTGFSLVISGVWCSDLNGA
                     VMTQAAFNGAIPTFGPILLTVSLTLFAFTTILGWSYYGERCFEFLFGVKGMNGYRTVF
                     VAMVLLGAFLKLEVVWIIADIVNGLMAIPNLIALLALSPIIVSETKKYFEHINSPENQ
                     IKKNA"
     regulatory      complement(10301..10389)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00504"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="glycine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="glycine"
                     /db_xref="RFAM:RF00504"
     gene            10817..12937
                     /locus_tag="KR231_003201"
     CDS             10817..12937
                     /locus_tag="KR231_003201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440272.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase III"
                     /protein_id="HBH0005542.1"
                     /translation="MGKILVLAEKPSVGRDIAKVLGSKNEKNGYIEGPKYVITWALGH
                     LVTLADPESYGERYKSWSLEDLPILPKHLKTVVIKKSGKQFNTVKSQMNRNDIDEIVI
                     ATDAGREGELVARWIIEKSQVKKTIKRLWISSSTDKAIKDGFAKLRSGKEYENLYYSA
                     IARAEADWIIGINATRALTTKYNAQLSCGRVQTPTLAMLLKREEEIRNFKPKEYYGLE
                     LIATKGNSDIKFIWNDKNNNSSTFSKEKIESTLKKVKGVDIKISEVNKSYKKKYSPAL
                     YDLTELQRDANKMFGFSAKETLSIMQKLYEHHKVLTYPRTDSRYLTSDIVGTLKDRIK
                     AVNISDYSKTCNKLLKSNIIANKSFVDNSKVTDHHAIIPTEQKVFMSDFSDKERKIYN
                     LVVKRFLAVLSPPFEYEQTTISATVEGEIFKAKGNKVINLGWKESYKDIEDEDEYESI
                     PNILEKDVLKVKGLKITSGKTNPPPYLNEGTLLTAMEKNGLGTVATRADIIEKLFNSF
                     LMEKKNKDIYITSKGRQLLDLVPVDLKTPELTASWEKKLLDISKGKLSKNTFINDMKD
                     YSKDIVLEVKNSDNKFKHDNLTKNRCPECGKFMLEVNGKKGKMLICEDRECNTRKTIS
                     QVTNSRCPNCHKKLELRGEGEGRIFTCSCGYREKLSSFNKRKQEEKQKASKKDVNQYL
                     KNQNKNQETFNNPFAEALAKLKNK"
     gene            13041..14294
                     /locus_tag="KR231_003202"
     CDS             13041..14294
                     /locus_tag="KR231_003202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar protein FliS"
                     /protein_id="HBH0005543.1"
                     /translation="MDLSGIFKYYCKECENTWNNSSVELFENIETYSKDSQKKREKEL
                     DKLLNTISVHLERYPSDAVLRKMWVKKGEVFLQKTLEKENIFKLEKMDVEDRKKFLDI
                     TKQFIRDARKFDDDLPIGDIMQAMRNVWISNALQLLFGKEVYYSKANFAYSMLYPYTD
                     NYLDNTNIDKNDKILFNNWLEKRLLGEHIKSKDYHESKVSKMIDYIESVYPREKFTEV
                     YESLLLIFKSQVNSLKQHGKENHLCKEDLLSISIEKGGSSVLVDGYLISGLMTKEEIE
                     FCIGYGFLLQISDDLQDIKEDLKYNHKTIITEMSKEGTLDKVVNKLINFTIELIDSFK
                     INNKNKSVITMIKNDCLMLILFSVVYNAEFFSVGYIKEVEKFIPYTIDYSLEIEEKIK
                     EKFKNIDVLNNENEYKEMIDIICAE"
     gene            complement(14447..>15432)
                     /gene="ytvI"
                     /locus_tag="KR231_003203"
     CDS             complement(14447..>15432)
                     /gene="ytvI"
                     /locus_tag="KR231_003203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="sporulation integral membrane protein YtvI"
                     /protein_id="HBH0005544.1"
                     /translation="LKFLLPLLMPFVISFIIASILRPIIRLITNNTNLNRTLISIVIL
                     LIFYGLCIFLLVSFGVKIFASVSDVFFRLPEIYKSSIQPTLNTLFSKIDASTPNVNLA
                     LILGWDNISQSMMSLVASISTNALNAIASIASKTPAFMLKLIITLIASFFFTFDYQKI
                     VNFILKQFPEKSQFMIINIKNSSINALLKLLKAYAILLSVTFIELLIGLTILKVENAF
                     TISVIIALVDILPVLGTGSILTPWMIISLINGNINLAIGLLILYIIITVVRQILEPKV
                     VGHQIGLYPLITLMCMFVGAQLFGIAGLFGFPIAATIIKNLHDNGIITAFK"
BASE COUNT         6134 a         1751 c         2672 g         4875 t
ORIGIN      
        1 taaaatagaa agggttaaaa acacagttta ttataatttt tattgttgag tagatacgta
       61 ctattatata tgattgagca agtttttcaa tcataaattt ataaagtatt ttgcattaaa
      121 atttaaacaa agaattaaat tatttaagat tatgaataac taatacattt agtaaattac
      181 taaatataca aaatgtaaat acttatcaaa atgtataaat acttatgaca tctagttact
      241 tacagggttt aagtagaaaa aaatatcaaa gtaagtatgg catgatagtt gcttatatat
      301 ttatcaagaa aggagttatt aagcatggag ttgagagata aacttgtaaa catcataaat
      361 acagaaaata aaaaagatcc attaacagat gttcaaatag caaagttttt aagtacaact
      421 agagagaaca taactaattt gagaaaagaa cttaatataa gtaattcaag gcaaagaaga
      481 tatccttatt taaaatcagc aatttcggca atattacaaa agaataagaa tatttctgta
      541 tcagaaatta caagggaatt gatgacagaa ggctttaata tatctagaag agttgtggag
      601 gaacttttac ctaaagaaag tttagaaatg gatgtagtag aggaatctga agaagaatcg
      661 aatgacccat ttgaaactct gataggtaat aaagggagtc ttagaaatgc tgtagagcag
      721 gctaaatctg ctatattgta tccaccaaaa gggttaccaa cgttgattat tggggaaagt
      781 ggagttggta agagtttatt ttctagacat atgtatgagt ttgcaaagca aaaaaagata
      841 gtaaaagaaa gctccaattt tgttgtattt aactgtgctg attatagtga caatccacaa
      901 ttattattat ctttgttatt tggatataaa aaaggtgcat ttacaggtgc tgaatatgat
      961 acaccaggtc ttgtagaaga agctgatgaa ggagttttat ttttggatga aatacataga
     1021 ttgcctccaa aaggccaaga aatactattt tctattttag ataggggaaa gtttaggaga
     1081 ttaggtgaaa ctaatgctga aagaaaagta agtattatgt tgattggggc aactactgaa
     1141 aatgtagaga ctaatttatt attaacattc agaagaagga taccaatgct aataactttg
     1201 ccaccattac atgatagatt actaaaagag aaaatagacc ttatatacaa tatctttcaa
     1261 caagagtgta atagaataaa tgcaaaaata tttgtagata aaaatgtgat tgaaatactt
     1321 gcactaaaaa agtttagtgg aaatatagga caattacaaa atatgattca ggttctttgt
     1381 gcaagagctt ttatgaagtt tataaattcc aaagatgaag atagtgaatc gatagtagta
     1441 gtagatataa atgaagtttt aaagcttaaa gattctttta aagatgctgc ctttcaagag
     1501 attgaatata cagagataag aaaatatttg aaaaatgcta tatttatacc atttaattta
     1561 gaagaatcat cagtaaaagg aagtctttta agtgatgaat atatattacc agaggacata
     1621 tacaaaacaa ttgaaaagaa atattatgac ctaaaatccc tagacattga agatatagat
     1681 atagagaata ttttatggac ttttatttta aatagatttg ctgacttaaa gtttaatctc
     1741 gatagtaatg aagaaatttt ttcaatgagt gatttaaata gttttgtaag tgatagttta
     1801 gttaaactgg taaaagaact tatgaatgat atagttgaaa aaaatatgaa tttagaagta
     1861 aataaaaata tgttcaaata tctagcaata cacttagaag aagctataaa aagaattaag
     1921 ctaaatcaaa agataataaa tgtaaattta gaaaaaataa agattgactt ttcaaaagaa
     1981 tatgaaatta gtaaaagttt tgcaataaaa attgaggaat caattggtat taagattcca
     2041 gatgatgaaa ttggatttat aacactctac ataaagtctg ctctaaaaaa tgaagtgaaa
     2101 aaagataaag tagggttaat aataatttct catggacgta tagctacaga gactgtaaat
     2161 gtagttaaag aacttttagg tgtaaagttt cctgtggcta tagatatgcc tttagatgaa
     2221 aaaccaataa atatatacaa taaggcagta gaactgtcaa aaataataga ccaagggaaa
     2281 ggcatattgt ttttggtgga tattggttca cttacaaaca taggtcaaat agtaaataag
     2341 agaaccaata taagcactaa aactattgat agagtagacc tcctaatggc actagaagca
     2401 actagaaaag tttctatggg agaggaagaa cttgatgaaa tatttttttc tttgctaaaa
     2461 gataggatgg gatataacta tgaattagaa aaacacatag ataaatcaaa tgcaattgta
     2521 acattatgtc ttactggaga aggaactgct aagtatataa gtaaaacgtt ggaagaaaag
     2581 tatgataaca ctaaatgtta tcaaatgagt gcattggatg aaaatttatt ttgtaaaatt
     2641 gaaaatctaa aagagacaaa caatatatta gctattgttg ggacaataaa ccctaagata
     2701 ccaggtataa attttatacc ctataataaa gaacttttca aaaatttgga tatctatcta
     2761 tcaaaatcaa aacaacaaga tgacagacca gttaaatcgt atgaaagaat gcttgatgag
     2821 gatttagtga tttttgaacc agatatatat tttaaaaagg atttattaga atatgtatgt
     2881 tcaattctta taaataaaga atatgtagaa aaagattact tagattctgt tttacataga
     2941 gaagaaatgc ttccaacata ttctaaagga gctataggtg tgcctcatgg agattcttct
     3001 actgtaaata gtacaaggtt tgtttttgtt aaactaaaga atcctattga ttggggtgta
     3061 ggtaatgtaa atttcatatt tatgccagtt tttcaggcta atgataaaga gattgttaaa
     3121 aatgttcttg agatactaaa agatgcagaa tttatgaaca atgccaataa gtgttttgat
     3181 aaagatgctt ttagaaggat tatatttgat aaatttaaac atctgtagcc atagcaaaaa
     3241 aattgagagg agttagagta atgaatgtag atttaatatc attgggttta gaatctaatg
     3301 attatgaaag tgttattgaa gaattaggaa gtataatgtg taaaaaagaa tatgtaaaag
     3361 aaacatacat aaatgctgtc ttggaaagag aaaggacatt accaacaggt ctagatattg
     3421 gagaaatgtg tgttgctatt ccacatacag attcaaagca tgtaaatgag tctaatgtag
     3481 ctgtagggat attgaaaaat cctgtaaagt ttaattcaat gatagaccca aaagatagac
     3541 ttgatgtaga acttgtattt ttattagcag taaagaaccc agattcacaa gtaaaactgt
     3601 taaaggattt aatgtcagtt tttcaaaata taaagttatt aaaaaatata aaaaacgcat
     3661 caacaaaaga agaagtagct aaattattgg attttataga aatttaatgt aggagaattt
     3721 tataaataaa aaattaaaat ttaaacaatc aaagtaagta ttattttttt aataggttta
     3781 atcttatata aaataaaaat ttagagtgaa aaattaggag gaaattatta tgaaacaatt
     3841 taatgtatta tcagtttgtg gttcagggac agttacatca tctatggtag caggtaaatt
     3901 aaaagaagta ctaggtaata aggggatttc tattactaca acagaagcta gaccaacaga
     3961 agcactaaat ttagcacaat caggaagatt tgactttata acatttacga gtccacttca
     4021 aacaggcgat tatggaatac caactataaa tgcatttgct tgcctaactg gtatagggga
     4081 agaggcattc tttgaagaag ttttgactgt tattgaaggg atagataagt aagttttgga
     4141 gacgtgaatt tatagtattt aaatcaatga tttagatact ataataagct aatattaact
     4201 aaatatttgt ggaaaaaaca ttttatatgt tgtcataaat taaaaaatta taaaaatagt
     4261 cacttaagta ttaaattaag cttataaata tttataagta ggagggaaaa agatgttaga
     4321 atttatgaaa tctataatcg atacatttgg ttctgcaatt atagttccaa ttataatatt
     4381 cataatagca aagatattta aagtaactac taagaaatcg tttctttctg ctgtgtatgc
     4441 aggagttgct ttacaaggtt ttacactgat tttaaattca tttacaccaa taataacacc
     4501 agttatcaat aggatggttg agagtacagg agtaaaccta ccagtttttg atgttggttg
     4561 gcaagcaaca tcattggttg cattttcaac aagtgcaggt atgatatatt taggtcttgg
     4621 tatattatta caaacaattt tatttttgat aaaatggaca gacgtgtttc aaccatcaga
     4681 tttatggaat aactattctt atatggtatg gggagcaatg gttataggag taacaggaaa
     4741 ttttccttta ggtatagcat gtatggtttt attaaaccta tatagtttat taatatcaga
     4801 gttagttgca aagagatggt ctagttacta tagatatcct aattgtacaa taatagctat
     4861 gcataatgtt gaagcttctg tgtttgcagt atttgcagac cctatataca ataaattggg
     4921 attaaataaa ataaaattaa atccaaaaga attagagaag aaattagggt ttttaggtga
     4981 accaattact ttaggtcttt ttttaggtat gtttataggt atattaggta atatgacgag
     5041 aataaatact atggaagctt ggggagaaat aatgaaagta ggtatatcta caagtgcagt
     5101 gatggcaatt ttccctaaag tagcaagtat gtttgctcaa gcatttgcac ctataacaga
     5161 agcagctaga aagattatgc aaaaagctgg aaaccgtgag tggtacatag cagtaaatga
     5221 tgctgttggg tatggtgaac ctgcaacttt aatatcaggt cttatattaa ttccaataat
     5281 gcttgtaata gctatggtac ttcctggtaa taaggtatta ccagttgtgg atttattggc
     5341 aattccatat atggttcaag gtttagttgc catacataat ggtaatatac caaaagtatt
     5401 ggtttcaggt ataatttggt ttggattagg attatatgtt tgtacatcta cagcaccatt
     5461 atttacagat atggctacaa atataggtgt agctatacct gcaggagcaa tgttaataac
     5521 aagctttaat atactaggaa aacctttgat gggattagtt ttctttgcat ttctaagtgc
     5581 aaatccaatt tatataggtc tttcagttgt aatttacttt gttctatggg cattgtttag
     5641 aaagaacaaa acaagtattc ttgattattt agaaaaacaa gcacttaaaa atgtagaaga
     5701 agagcctgta gcagtttaag tttataaaaa tgaaataaga ataattaaag gagtttataa
     5761 ttgattttat ataagtatca gataatacct gagaaatatt taaatgaaat atagacttct
     5821 ttttatttga taatatttgt aattataatg cattgtatct ttatagttga gttttctgta
     5881 taacctgcta tttaaaacat actcttttat atttatacag taatgtggtt taattttata
     5941 aaatgtaatc tctactggta aaagactttg tatataaggc atttgcctga ataaaccatt
     6001 tatcttttgt atggcataga tattgctata tagaagtata tagcatgaaa ggagatattt
     6061 atatgggaga taaaatgaga gcatcagtat tgtatagtgt aggtgatgtc agatatgaaa
     6121 tggtagatat accagaaata acagatacgc aagtgcttgt aaatgtaaaa tatgttggga
     6181 tatgtggttc agatttacct aggtctatgg taagtggttt gagtggaaat acaaaatatc
     6241 cattgatttt aggacatgaa ttttctggcg aagttgttaa aattggagaa aaagtaaagc
     6301 atattaatgt aggagataga gtagctgttg caccattagt accttgtgga aaatgtgatt
     6361 attgtaatga aggtaatttt ggcttgtgtg atgattacaa tataattgga acaagagtaa
     6421 atggagcgtt tgcagaatat gtaagagttc cagaagaaca tattttaaaa ctaccagata
     6481 cattggatta tgaaactgct gccggaattg aaccagcaac tatagcttat catgggattt
     6541 caaagtctaa tattagagta ggagatagtg tagttgtgtt aggatgtggt ccaataggtc
     6601 agtttgttat acaatgggca aaggtgtttg gtgcatctaa gattatagca gttgatattt
     6661 ttgatgaaaa attagaactt tctaaacttc taggagcaaa ctatatactt aactcaaaag
     6721 aagtaaatgt aatcaaagaa ataaaaaaaa taacaaatgg tggtgctgat gttgtaatag
     6781 agactgctgg tagccgattt acacaagaac aatctctatt tgtagcaaaa aagaggggaa
     6841 atatagtgtt tgtaggtata tcacacacag aattaccact tagtgcagac gctactgagt
     6901 gtatattacg tggagaactt accttgaaag gttcttggaa ttcatataca agcccttatc
     6961 ctggaagagc atggactgca acattggatt ttatgggaaa aggtgacatt atttttaaac
     7021 ccatgatttc acataaaata ggtcttaatg aagtgggtga ctttttaagt aaaatgagca
     7081 agagagaaat taatttcaat aaaatcctag tagaaatata aaaatttaat aaaaaattct
     7141 aaaagcaatt aaattttata actatgacat taaataaaat aaaaataatt ttcttaaata
     7201 aaatatagga ggaagaaaag tgttagaaaa tttaaaagaa gaagtattaa aagcaaactt
     7261 agaattacct aagaaaaagc taattactta tacttgggga aatgtaagtg gaatagatag
     7321 agaaaaagga ttagtggtga taaagccaag tggtgtagag tatagtaata tgactgtaga
     7381 agatatggtt gtagttgatt tagagggaaa tatagttgat ggcaaattaa gaccttcttc
     7441 agataccccg actcatctag ttttatataa agagtttgaa gaattggggg gaatagtaca
     7501 tacacattca agttgggcaa caatttgggc tcaaatagga aaatctatac catcttgtgg
     7561 tactactcat gcagattatt tttatggaag tataccatgt accagaaaaa tgactagaga
     7621 agaaatttgc aatgaatacg aaaaggaaac tggaaatgta atcattgaag aatttatggg
     7681 aagaaatcca attcattgtc caggaataat tgtaaatgac cacggacctt ttacatgggg
     7741 aaaagatgca aatgaggctg tacacaatgc agtagtttta gaagaagtcg caaagatggc
     7801 ttattataca gagttaatga gtcctgataa tattatggat aaggttctta tgaataagca
     7861 tttttcaaga aaacatggaa aaaatgcata ctatggtcaa aaatgattat ctggaggtga
     7921 attatgctag actctttaaa aggtaaaatt gtggaaatag caattaaagc agagcattat
     7981 ggtttatgta aagaaaagac tggtaatttt agtattagag ataaggatac tggatatata
     8041 cttataaccc catcaggtgt aggaagagaa gaattaaaag ttgaacatat ttgtgtattg
     8101 gatttggatg gaaatgtaat agaagttgag aaaggtatta agccaagtag tgaggtattg
     8161 atgcatattg aaatatacaa aacaagagaa aatataaatg ccatatcaca tactcattct
     8221 ttatatgcaa cagcattttc agtagcaaag aaaccaatta taccaattgt atatgaatca
     8281 gttaattatg gcggttatgt agatattgct ccatatgaaa gaccaggaac tttaaaatta
     8341 gctaagagtg tttcaaaatt actgatagat acagatgcat gcttattaga aagacatggg
     8401 ttgacaactg taggtaatga tttagacgaa gcattattaa aatcaagata tgtggaagag
     8461 gtagcagaaa tatactatag gtctttagta ttaaatcaat ttaaagaact tgaagtagta
     8521 gatgttgatg agtttaaatc ttggaaatac ccagaagaaa taaagtttta atctaaataa
     8581 ttttcattga agtggttaat taaaatatat gtattattta tatcaattac tatgttttat
     8641 tatgttaatt accgtatttt gcaaatatat ttattacatt ttttcaaaaa aatatagaat
     8701 ccgaaagcca tataaaattg acttgggatt ctatactttt tatttatgca tttttcttta
     8761 tctgattttc tggagaattt atatgttcaa aatatttttt agtttcagat actattatag
     8821 gtgataatgc aagtaaagct ataaggttag gtattgccat aagcccattt acaatatcag
     8881 caattatcca aacaacttct aactttaaga aagcacctaa taacaccata gccacaaata
     8941 cagttctata cccattcatg ccttttacac caaacagaaa ttcaaaacat ctttctccat
     9001 aataactcca tcccaaaatt gtagtaaatg caaataatgt taaactaact gtaagtaata
     9061 ttggtccaaa tgtaggaatt gctccgttaa aagctgcttg tgtcataaca gctccattta
     9121 ggtctgaaca ccacactcct gaaataacaa gagagaatcc agtaagagta cagattataa
     9181 tagtatctat aaaagtacct gtcatagata taagaccttg ttccgctggc cattcagttt
     9241 tagcagcagc agcagctatt ggagcactac ctagaccaga ctcatttgaa aatacaccac
     9301 gagcgatacc atttctaatt gccagtgaca tagttgctcc taaaaaacca ccagtagcag
     9361 cagtaggtgt aaatgcactt ttaattatta acataaaagt ttcagggatt ttattccaaa
     9421 aagatattaa aatgattcca cagattacaa catatataac tgccataaaa ggtactattt
     9481 tagtagctac attagatata cttttaagtc ctccaaatac aaccaaagct acaaatactg
     9541 ctaatacaac ccctgtaatt ctagggtcta tcccgaaact attatttatt gcatctgtta
     9601 ttgaatttac ttgagtaaaa gtaccgattc ctaaaagtgc aactagtata ccacttatag
     9661 cgaaaaatat tgcaagaggt ctccattttt ctcccatacc atttactatg taatacattg
     9721 gcccaccaga cacttggcca tttttatctt tagttctgta ttttattgca agaacacctt
     9781 ctgaatactt agtagccatt ccaaagaatg ctgctatcca catccaaaaa agtgcaccag
     9841 gtccaccagc tttgatagct gtagcaacac caacaatatt accagtacca actgtagcag
     9901 ctagagcagt acataaggct gcaaaacttg aaacatcacc actacctttg ttttcagcag
     9961 agaatattaa cttaagagct cttggcagtt tagttatttg aacaactcca agcttaacag
    10021 taagtagtat accagtacca actaatagta ccagtagggg tggtccccaa ataaaagcat
    10081 caactttgtt taaaatatca attagattca taaaaacact ccctcatttt ttttgcttta
    10141 cataatcaat agaattttta atgaagtaat tgacaggaaa taagtataat ttattaataa
    10201 tttctagtgt aataaaaaaa gctaaatcta aaaaagattc agctctggat gtacactaat
    10261 tagcaaccaa aataaaagta ttagtaaata ctgtttttgg tagataatcc ctgtcctttt
    10321 gcctgagaga ttgagcataa aagccttgcc ccttcggcgc ccataatggg tctctccaga
    10381 gttccgtaaa ttttacagtc ctacttttaa aagtacctga gagtgttact ccttcggtgt
    10441 gctatatagc aactcttcta taaaatctta accggatatt gatttgtcat agcttattgt
    10501 attaataata ttaatataag tttttatgtt ttgtcaacta aaaaattaaa aaacaaagaa
    10561 aaaatataaa aatgtaagcc tatttacgaa ttataaactt agaaagatga gtaatatacg
    10621 tgaaaatgaa ttttgtaata cacatacaaa tgaagtgtaa aataagttct aaataaaaaa
    10681 ataataaaat cttaaataat taattagata tgattaaatt atggtaatat tatagttacg
    10741 atattaagaa aagttctatt tagttagatt ttaagcgtaa tatgagatta tgtatagaga
    10801 aaggatgtat ttttagatgg gaaaaatatt agtgctagca gaaaaacctt ctgttggaag
    10861 agatatagca aaagttttag ggtcaaaaaa tgaaaaaaat ggttatatag aggggccaaa
    10921 gtatgtgata acttgggcac taggtcattt ggttacactt gctgaccccg aaagttatgg
    10981 agaaagatat aaatcatgga gcttagaaga cctgccaata cttcccaagc accttaagac
    11041 tgttgtaata aaaaagagtg gaaagcagtt taatacagtt aaatcgcaaa tgaatagaaa
    11101 tgatatagat gaaatagtta tagcaacaga tgcaggtcgt gaaggagaac ttgtagcaag
    11161 gtggataata gaaaaatcac aggtaaaaaa aactataaaa cgtctttgga tttcttcaag
    11221 tacagacaaa gcaataaaag acggatttgc aaaattaaga agtggaaaag aatatgaaaa
    11281 tttgtattac tcagcaatag cacgagcaga agctgattgg attattggaa taaatgcaac
    11341 cagagctttg acaacaaagt acaatgcaca gctttcttgt ggaagagtac aaactcctac
    11401 tcttgcaatg ttgcttaaaa gagaagaaga aataagaaat ttcaaaccta aagagtatta
    11461 tggattagaa ttaattgcta caaagggaaa ttcagatata aaatttattt ggaatgataa
    11521 aaacaataat tcttcaactt ttagtaaaga aaagatagaa tccacattaa aaaaagtaaa
    11581 aggtgtagac ataaaaatat ctgaagtaaa caagtcatat aagaaaaaat attcacctgc
    11641 actctatgat ttaacagaat tacaaagaga tgcaaataaa atgtttggat tttcagcaaa
    11701 agaaacttta tctataatgc aaaaactgta tgaacatcat aaagtactta cttatcctag
    11761 aactgattct agatatttaa catcagatat tgttggaaca ttaaaagata gaataaaagc
    11821 tgtaaatatt agtgattatt caaagacttg taataaatta ttaaaaagca atattatagc
    11881 taataaatcg tttgttgaca attcaaaggt aacagaccat catgcaataa taccaacaga
    11941 acagaaggta ttcatgagtg attttagtga caaagagcga aaaatatata atcttgtagt
    12001 aaaaagattt ttagcagtac tatctcctcc ttttgaatat gagcagacaa ctataagtgc
    12061 aactgtagaa ggagaaatat ttaaggctaa gggaaacaaa gtaataaatt taggttggaa
    12121 agaaagttat aaagatattg aagatgaaga tgagtatgaa agtataccaa atattttaga
    12181 aaaagatgta cttaaggtca agggattaaa gataacttca ggaaaaacaa atccaccacc
    12241 atacttaaat gagggaacat tattgactgc tatggaaaag aatggtctag ggacagttgc
    12301 tacaagagca gatataatag aaaaattatt caattcattt ttaatggaaa agaaaaataa
    12361 agatatatat ataacatcaa aaggaagaca attattagat ttagttccag tagacttaaa
    12421 gacaccagaa cttacagctt catgggaaaa gaaattattg gatatttcaa agggaaaact
    12481 tagtaaaaat acattcataa atgacatgaa agattattca aaagatattg tactagaagt
    12541 aaaaaatagt gataataaat ttaaacatga taacttaact aaaaatagat gtccagaatg
    12601 tggtaaattt atgttagagg taaatggtaa aaaaggtaag atgttgattt gtgaagatag
    12661 agagtgtaat actagaaaaa ctatatcaca agtaaccaat tcaagatgtc ctaactgcca
    12721 taaaaaatta gaacttcgtg gagaaggtga ggggagaatc ttcacttgta gttgcggata
    12781 cagagaaaag ttgtcgtctt tcaacaagag aaagcaagaa gaaaaacaga aggcatcaaa
    12841 aaaagatgtt aatcaatatt taaaaaatca aaataaaaat caagagacat ttaataatcc
    12901 atttgcagaa gcattagcta agctaaaaaa caaataattt taaagttatt attatacaca
    12961 attataactt taactgtata ttagttatat gtactgatat aatatagtgt atagtttagg
    13021 catgaaagta gggctgttaa atggatttaa gtggcatatt taaatactat tgtaaagagt
    13081 gtgaaaatac atggaataat tcgagtgttg aattatttga gaatatagaa acgtatagta
    13141 aagattcaca aaaaaagagg gaaaaagaat tagataaatt gctaaataca atatcagttc
    13201 atttagagag gtatccaagt gatgctgtat tgagaaaaat gtgggtaaaa aagggcgagg
    13261 ttttcttaca aaagacattg gaaaaagaaa atatttttaa gttagaaaaa atggatgtag
    13321 aggatagaaa aaaattttta gatataacaa aacagtttat tagagatgct agaaaatttg
    13381 atgatgattt acctataggt gatattatgc aagctatgag gaatgtatgg atttcaaatg
    13441 cattacaatt attatttggt aaagaagtat attattcaaa agctaacttt gcatatagta
    13501 tgttatatcc atatactgat aattatttag acaatacaaa tatagataaa aatgataaga
    13561 ttttatttaa taactggtta gaaaaaaggc tcctgggaga acacattaaa tctaaggatt
    13621 atcatgaaag taaagtatct aaaatgatag attatattga aagtgtatac cctagagaaa
    13681 agtttacaga agtttatgaa tcgttattat taatatttaa aagtcaagta aatagtttaa
    13741 aacaacatgg taaggaaaat catttgtgta aagaagattt attatccatt tctattgaaa
    13801 aaggaggttc atccgtttta gtagatggat atttaataag tggattgatg acaaaggaag
    13861 aaatagagtt ttgtatagga tatggatttt tattacaaat atctgatgat ttacaagata
    13921 taaaagaaga tttaaaatac aaccataaaa ctattattac agagatgtca aaagagggta
    13981 ctttagataa agttgtaaat aaactaataa attttactat tgagttaata gatagtttta
    14041 aaattaataa taaaaataaa tctgtaataa ctatgataaa gaatgattgc ttaatgttaa
    14101 ttttattttc tgtagtttat aatgctgaat ttttttctgt aggatatata aaagaagtag
    14161 agaaatttat tccatataca atagattatt cattagagat tgaagaaaaa ataaaagaaa
    14221 aatttaaaaa tatagatgtt ttaaataatg aaaatgaata taaagaaatg attgatatta
    14281 tttgtgcaga gtagaaaaaa agggagtgtc ttagaataga ctttttagtt tatgaggcac
    14341 tctttttgta taaaatcaaa tgtattttca tcattttaat aattaaaaag agcttatccc
    14401 tatttgagaa agcccttttt aatttaataa aaatgtcaag gttaaactat ttaaatgcag
    14461 taataatccc attatcatgt aagtttttta tgattgtagc tgcgataggg aatccaaata
    14521 atccagctat tccaaatagt tgagctccaa caaacataca cattaatgtt attaaaggat
    14581 ataggccaat ttggtgtcct actacctttg gttctaatat ttgtctaaca acggttataa
    14641 ttatgtatag tattaaaagt cctattgcta aattaatatt tccattaatg agtgagataa
    14701 tcatccaagg tgtcaaaata cttcctgtac ccaagactgg caaaatatca acaagtgcta
    14761 tgatgacaga tatagtaaat gcattttcaa cctttaggat agtaagtcca ataagtagtt
    14821 ctatgaatgt cactgatagt agtattgcat aggcttttag tagttttaaa agagcattaa
    14881 tactgctatt ttttatattt attatcataa attgactttt ttctggaaat tgttttaaga
    14941 taaagtttac tattttttga tagtcaaaag taaagaaaaa agaagcaatt aaagtaataa
    15001 taagttttaa cataaatgca ggtgttttac ttgcaatact agcaatagca ttgagtgcat
    15061 ttgttgaaat agaagctact aaagacatca tagattgact tatattatcc caaccaagta
    15121 ttaatgctag gttaacatta ggtgtactag catctatctt tgaaaataaa gtatttagcg
    15181 ttggttgtat acttgattta tatatttcag gaagtctaaa aaatacatca cttacacttg
    15241 caaatatctt cacaccaaag ctaactaata aaaatataca caacccataa aaaattaaaa
    15301 gtattactat agaaataagt gtacgattta aatttgtatt atttgtaata agtcttataa
    15361 taggtcttaa gatggatgca atgataaaac tgattacaaa aggcattaat aatggcaata
    15421 agaattttaa ta
//
LOCUS       DAEPHU010000090        15164 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 01A10CD0081
            SAMN05941466-rid12468953.denovo.090, whole genome shotgun sequence.
ACCESSION   DAEPHU010000090 DAEPHU010000000
VERSION     DAEPHU010000090.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941466
            Sequence Read Archive: SRR6291087
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 15164)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15164)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068158.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 22:43:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,892
            CDSs (total)                      :: 3,805
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 87
            rRNAs                             :: 8, 1, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 55
            CDSs (without protein)            :: 55
            Pseudo Genes (ambiguous residues) :: 0 of 55
            Pseudo Genes (frameshifted)       :: 21 of 55
            Pseudo Genes (incomplete)         :: 28 of 55
            Pseudo Genes (internal stop)      :: 16 of 55
            Pseudo Genes (multiple problems)  :: 8 of 55
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15164
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941466-rid12468953.denovo.090"
                     /strain="01A10CD0081"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            239..1162
                     /locus_tag="KR231_003204"
     CDS             239..1162
                     /locus_tag="KR231_003204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2520 domain-containing protein"
                     /protein_id="HBH0005545.1"
                     /translation="MGSGKVGTSLANYFLSKGYCVSGFYGRNQLSLLESTNLTKTKIY
                     SNLKDIIYENDILFITTSDDSIEIIDKKLSKFNLKHKYICHTSGSLKSSILFCSKKAG
                     ALIYSIHPIFAFSNKNTNIKKMKDICFSIEGDNEQDDLVIQNFIDDLGNQFFIRDKDT
                     SSTYHLANVLVSNLVLSLLDIGVSYFIKLGLSEEESLKAISPLVKKNIENILDNGFTK
                     ALTGPVSRGDITPIRKHLSVLDKKDEDIYKILSLNLLKIIALGNDNSLKGIKNITIEN
                     AIENLISKSEKYKEIYKLLGGKNDEKYHTDF"
     gene            1137..1964
                     /gene="panB"
                     /locus_tag="KR231_003205"
     CDS             1137..1964
                     /gene="panB"
                     /locus_tag="KR231_003205"
                     /EC_number="2.1.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011721175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-methyl-2-oxobutanoate
                     hydroxymethyltransferase"
                     /protein_id="HBH0005546.1"
                     /translation="MKNTIQTFKNAKYEGKKLSMLTAYDYSIAKIMDECDINGILIGD
                     SLGMVIKGEENTLSVTIDEIIYHTKAVKNGVKNALIVSDMPFLSYHVSIEDAVKNAGR
                     LIKEGGAHAVKLEGGSNVIKQIESIVNAQIPVMGHLGLTPQSVNSFGGFKVQGNTSET
                     ARQLIEDAKLIEKAGAFSIVLEGVPTKIAEMVTNSISIPTIGIGAGINCDGQILVYQD
                     MLGMFGDFVPKFVKQYANIGDIMKDSIKNYILEVNTGTFPQEKHSFSINESELEKLY"
     gene            1983..2831
                     /locus_tag="KR231_003206"
     CDS             1983..2831
                     /locus_tag="KR231_003206"
                     /EC_number="6.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pantoate--beta-alanine ligase"
                     /protein_id="HBH0005547.1"
                     /translation="MLVKEIKLLRNIIKDWRKHGYSIGLVTTMGFLHEGHQSLIKKAV
                     KENDKVVVSVFVNPTQFGPNEDFNSYPRDIDKDFKYCMDSGATVVFNPSPEEMYLKGN
                     CTTINVSGLTDFLCGAKRPVHFGGVCLVVSKFLNIVTPDKAYFGEKDAQQLAVIKRMV
                     KDLNIDTEIIGCPIIRENDGLAKSSRNTYLSEEERKSALILNKSLSLAKEELVKGNLN
                     PENIKELITAKINSEHLAKIDYVEIVDSETLQPVKQIEHSILVAIAVFIGKTRLIDNF
                     TFELNI"
     gene            3242..3424
                     /locus_tag="KR231_003207"
     CDS             3242..3424
                     /locus_tag="KR231_003207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0005548.1"
                     /translation="MFKDKIDECVHIMTAYIASLKEYYSFIETQIGDFIKKYGEDVVE
                     LCLHRVMILLCECGLA"
     gene            4256..5170
                     /locus_tag="KR231_003208"
     CDS             4256..5170
                     /locus_tag="KR231_003208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2935 domain-containing protein"
                     /protein_id="HBH0005549.1"
                     /translation="MIDNQKYVILSLELHLFFSRIMKEHALFLEAGFTNKNYNLAMEA
                     DHYKKQFEDLLSYTVSASNGIIRPDILYSEELVTTLTSVAEQKTEEFTGIEINKNITT
                     RELNLQSGVNPQVGQDLVNYVAQLNSDAIRLLDGLINFKERVLDGVLSCTIFTSNYPL
                     LLEHIIHEANLYRYYVVDLENKIDIESKNAKEIELFWDHIMMEHALFMRGLLDPSEGE
                     LINTSNDFAIKFNELIEKTNEMTDSNIKNITEETLNETVEFKDFKEAGASGIEQCKIK
                     SIILPLLADHVLREANHYIRILESYKNM"
     gene            5560..6207
                     /locus_tag="KR231_003209"
     CDS             5560..6207
                     /locus_tag="KR231_003209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactate utilization protein"
                     /protein_id="HBH0005550.1"
                     /translation="MIRQTPLEKRYDKLGPHIVTALKKRYFDAYYCKTRNEALQQILD
                     LIPQNHVVSWGGSETLKEMGVQTAVREKGFKVIDRDLAKTPEERTEIMRQALLCDTFL
                     MSSNAISEDGQLFNIDGNGNRVAAMIFGPKNVIVVAGMNKIVKNIDDAIQRTRTIASP
                     AVVQRFQDVNTPCYINGSCIDCTSPESICAYMVTTRISRPAKKIKVILVGENLGL"
     gene            complement(6374..6943)
                     /locus_tag="KR231_003210"
     CDS             complement(6374..6943)
                     /locus_tag="KR231_003210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein"
                     /protein_id="HBH0005551.1"
                     /translation="MKKFIICIIMFAISVLVLAGCTNDNKIKNEVDSMFNSIKTQDAD
                     TVDKYFPKSGLGNLIYEDKEGFKMYSKNMTWEISDIKNNKDKVTVDLKINNTDMVSIL
                     KKNPPKLGEMMPNPTMKDIDSAKKKEFNITLELVKSGDNYVCKVNQESAMKLLNVITG
                     GGIDYLADYNKDYYKQLDEEQKNYENKNS"
     gene            complement(6948..7847)
                     /locus_tag="KR231_003211"
     CDS             complement(6948..7847)
                     /locus_tag="KR231_003211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S binding protein"
                     /protein_id="HBH0005552.1"
                     /translation="MKLLSKVNNNIRLITQVAFTALTNGYVNGFLEGTIYGGESKKLC
                     VPGLNCYSCPGALGACPIGSLQAVLSSREYKFSFYVVGFLMAFGAFFGRFVCGWLCPF
                     GLVQDLLHKVPFPVKIKKVYGDKYLKYLKYIVLIMFVIILPVAIVNVAGGGNPWFCKW
                     ICPSGTLLGGILLILGNENLRESIGFLFSWKLSILLLILLMSIITYRPFCKYICPLGA
                     IYGFFNPISIYRFKIDKDKCTNCTACQTKCKLDIPIYKDVNSPDCIRCGECIKVCPQN
                     AITTTFSKDKKENNICAKKYRGI"
     gene            complement(7858..8007)
                     /locus_tag="KR231_003212"
     CDS             complement(7858..8007)
                     /locus_tag="KR231_003212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0005553.1"
                     /translation="MSNFIKDNKKGISIIAISIIFIALGTYRGETNTVLTKAIMICLE
                     CIGIG"
     gene            complement(8000..8584)
                     /locus_tag="KR231_003213"
     CDS             complement(8000..8584)
                     /locus_tag="KR231_003213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TlpA family protein disulfide reductase"
                     /protein_id="HBH0005554.1"
                     /translation="MKRFFIVVLGCICVLGMISGCSKKESKPVEKNKNNSEWFSNLDT
                     EDVDGNKVTKEIFSNKELTLINVWTTWCGPCVGEMPELEALSKEYESNNSNVAIKGLV
                     VEVDKTDMRTGLSNEEKNLVKDIMKKSDATYQQLTVSEELKKTDFKRVMEFPTTYFVD
                     KKGNFVGEKVVGANSKEDWKKIIDERLKMVKANE"
     gene            8973..10298
                     /gene="cdeA"
                     /locus_tag="KR231_003214"
     CDS             8973..10298
                     /gene="cdeA"
                     /locus_tag="KR231_003214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MATE transporter CdeA"
                     /protein_id="HBH0005555.1"
                     /translation="MENLFTRKFTTFEFLKFVSPAIISMIFISLYTIIDGIFVSTLVG
                     SDALASINIVLPIINLVCGFGIMMATGGGAIVSIRMGENRQDEANSTFSFIVLFSLIV
                     GILFTVISYFFIKEISILLGATDKLLPYCITYGKVMILCTPFYILKFIFEYFARTDGN
                     SKFSLFLSVIGGVTNIILDYVFIKYFGMGLLGAAVATAIGIILTCVLGIIYFLSNKST
                     LKLRKPKTDFRLIRDTMINGSSEMVTELSTGITTFLFNVVALKLAGENGLAALTIVLY
                     AHFLMTSVYLGFAAGVSPLISYNFGAENSDKLKETFKHSLKFIFISSLLVFIIALVFA
                     PFIVRVFVNPDNTVFKLALQGLKIFAFAFLFVGINIFASGFFTAFHNGKISAIISFSR
                     AFVFIIIGIIILPPMLNMTGLWLTVPFAEVITIFISILFIKKYKCRYKY"
     gene            complement(10393..11187)
                     /locus_tag="KR231_003215"
     CDS             complement(10393..11187)
                     /locus_tag="KR231_003215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBH0005556.1"
                     /translation="MNELKPYIKFFNKNTKLYIIIFMIVGIVMNILPVFILKIFGEAS
                     KTNLSTIVNPILTYITILLFVYGVNIANKDFSGALSIRADRKSCIKAIVIDLIILSFV
                     ISILGIVLIFLSKLFIEIITGYSIELSVLLKRDMIWTSISALIDPSTSSMPLTYLNYF
                     VQICINEICIGFIGVLLGAFTYRVRKVTSITILIGLPILMVIYIVNFATKNMHKMLLY
                     LEKIIYSFQNPFILFGTKVGIIVICIIFIILLLRKAPIKEYANDLL"
     gene            complement(11188..12063)
                     /locus_tag="KR231_003216"
     CDS             complement(11188..12063)
                     /locus_tag="KR231_003216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH0005557.1"
                     /translation="MSSSIKIENLSHSFKKQNIFNNMSLNFEKNKIYGLLGKNGAGKT
                     TLLNIMVNQLIQNEGEIEILGKNPKEDIKVLEEVCIVREKEFYSPDFKVGQIFEFSSS
                     FYKSYDKGLEKELCKYFDLNTKKKYKQLSRGMKTILSNIIGICSNSAITIFDEPTIGL
                     DAVNRQEFYNIILDSYIKNPRTIIISTHLIDEIDDLLEHVIILNEGKIIIDEEIDVIK
                     QKAHYITGNKEELEKLECIKNIKPKKAFGNAVAYFYYGDFSENDEKILKNSNIDVGYI
                     GLQDMFVNMTKKEEL"
     gene            complement(12067..12435)
                     /locus_tag="KR231_003217"
     CDS             complement(12067..12435)
                     /locus_tag="KR231_003217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBH0005558.1"
                     /translation="MKLVLNNEEPIFIQIARAIEDEILSNGIKEEEQVPSTTELSKLY
                     KINPATVLKGINILVDKNILYKKRGIGMFVSDGAKTIIKEARKENFKHNFVKNLLQEA
                     NKLEINREELVDIIINFKED"
     gene            complement(12618..13277)
                     /gene="deoC"
                     /locus_tag="KR231_003218"
     CDS             complement(12618..13277)
                     /gene="deoC"
                     /locus_tag="KR231_003218"
                     /EC_number="4.1.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribose-phosphate aldolase"
                     /protein_id="HBH0005559.1"
                     /translation="MKHILKTVDHTILKATTTWEDIKILCDEAVDMSVASVCIPPSYV
                     KRASEYLKGKIKICTVIGFPLGYQTTATKVFEAKDAIENGADEVDMVVNISDIKNKDY
                     DNIGKEIKEIKKAIGDKVLKVIIETCYLDEDEKIKMCEIVTMSGSDFIKTSTGMGTGG
                     ATLEDIKLMKEHVGKNVKIKAAGGVKSISDAEKFIEAGAERLGTSSICKILKNEDTTD
                     Y"
     gene            complement(13313..14500)
                     /gene="murJ"
                     /locus_tag="KR231_003219"
     CDS             complement(13313..14500)
                     /gene="murJ"
                     /locus_tag="KR231_003219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="murein biosynthesis integral membrane protein
                     MurJ"
                     /protein_id="HBH0005560.1"
                     /translation="MKQEPCDFSHGRFRTGIIFIGITSVMSAFLQIKENFIVVGFGSI
                     PYNIVIIISIMLSTIFGPYILPIGAVVAMVVQLLFYMFFVKKTNYKYLYYLNFKDDSL
                     IKLLALLSPVFIGVAVNQVNSLVDTTLASTLVKGSIPALTYADRLNGFVTGTFTASIV
                     SVMYPMLSKLSAENNQKKFTSSVKSSINMIIISMIPISVASIFFATPVVRIIFERGAF
                     DARATQMTATALIFYAVGMTAFGLRDILGKVFYSLQDTKTPMVNGIISVGVNIVLDLV
                     LIKPMAHGGLALATSSSSIACILLLFLNLKRKVGYFGQDKIIKATLKSVVASLIMGVL
                     SYFTYKFIFGILGVGTFNEFVSLAISVIVGGGIYTLLMTIFKVEEVDMILNIAKRKLH
                     LKK"
     gene            complement(14577..>15164)
                     /locus_tag="KR231_003220"
     CDS             complement(14577..>15164)
                     /locus_tag="KR231_003220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HBH0005561.1"
                     /translation="TNNQIGLDLGIKEFCISSCGEFIENPKYFKKSLNKLAKLQRELS
                     RKTIGSLNRNKARLKVARLQEHIANQRNDFLQKLTTKLIKENDIICIEDLQVKNMIKN
                     HKLSRLISDVSWSEFIRQLEYKANWHGRQIVKVGKFFASSQICNKCGYKNEEVKNLNI
                     REWICPSCNETHDRDINASRNILKEGLRLITIQNK"
BASE COUNT         5441 a         2212 c         1832 g         5679 t
ORIGIN      
        1 cttatatttt ataaatatca taattttttt actgatattt tattatataa attttataga
       61 attaattgtc aattttttat gaaaatggta agatatttat ggatggtatc ttgttataag
      121 aactatactt taaatgtttt taattatttt gtcttatgta actcatatcc tcaggaatga
      181 gattagaaat taagatgttg tatcacaaag tggaggtgat actattaaaa taggctttat
      241 tggttctgga aaagttggaa catctttggc aaattatttt ttatcaaaag gttattgtgt
      301 ttcaggcttt tatggaagga atcaattatc tttattagaa tcaacaaatt taacaaaaac
      361 aaagatttac agcaatttga aagatataat ttatgaaaac gatatattat ttattacaac
      421 atcagatgat tctattgaaa ttatagacaa aaaactttcc aaatttaatt taaaacataa
      481 atacatttgc cacacaagtg gctctttaaa atctagtata ttgttctgtt caaaaaaagc
      541 aggtgcatta atttattcta tccatcctat atttgcattt tccaataaaa ataccaacat
      601 aaaaaaaatg aaagacattt gtttttccat agaaggtgat aatgaacaag atgatttagt
      661 tattcaaaat ttcatagatg atttgggaaa ccaatttttt ataagagata aggatacttc
      721 atccacttat catttagcta atgttttagt ttcaaattta gtattatctt tactagatat
      781 aggagtaagt tactttatta aattaggttt atctgaagag gaatctttaa aagctatcag
      841 tcctttagta aaaaaaaata tagaaaatat acttgataat ggctttacta aagctcttac
      901 tggtcctgtt tctcgtggag atataacacc aataagaaaa catctatctg tattggataa
      961 aaaagatgag gatatttaca aaatactatc cttaaaccta ctaaaaataa ttgccttagg
     1021 aaatgacaat tcattaaaag gtataaaaaa tattactata gaaaatgcaa tcgaaaattt
     1081 aataagtaaa tctgaaaaat acaaagaaat ttacaaactt ttaggaggaa aaaacgatga
     1141 aaaataccat acagactttt aagaatgcta aatatgaagg aaaaaaacta tctatgctta
     1201 ctgcttatga ctactcaatt gcaaaaataa tggatgagtg tgatataaat ggtattttaa
     1261 taggagattc attaggaatg gttataaaag gtgaagaaaa cactctatct gttaccatag
     1321 atgaaattat atatcataca aaagctgtaa aaaatggtgt aaaaaatgcc ttaatcgtaa
     1381 gtgatatgcc ttttctatct taccatgttt ctatagaaga tgcagttaaa aacgcgggta
     1441 gacttataaa agaaggagga gctcatgctg taaagttaga aggtggctca aacgttataa
     1501 agcaaataga aagcattgta aatgctcaaa tacctgtaat ggggcattta ggattaactc
     1561 ctcaatcagt aaattcattt ggtgggttta aggttcaagg aaataccagt gaaacagcaa
     1621 gacaacttat tgaagatgct aaattaatag aaaaagcagg tgcattctct attgtccttg
     1681 aaggagtgcc tacgaaaata gctgagatgg taactaattc tatttcaatt cctacaatag
     1741 gtataggggc aggaattaac tgtgatggac aaattttagt ttatcaagat atgttgggaa
     1801 tgtttggaga ttttgttcct aagtttgtaa agcagtatgc aaatatagga gatataatga
     1861 aagattcaat taaaaattac atcctagaag ttaatacagg tacatttcca caagaaaaac
     1921 acagcttttc aataaatgaa tctgagttag aaaaattata ctaatattaa ggatggtaca
     1981 aaatgcttgt aaaagaaatt aaattactaa gaaatataat caaagattgg agaaaacatg
     2041 gctattctat agggcttgtt acaacaatgg gatttttaca tgaaggacac caaagtctta
     2101 taaaaaaagc tgtaaaagaa aatgataaag tagtagtgag tgtatttgta aatccaactc
     2161 aatttggacc aaatgaagat tttaatagct atccaagaga tatagataaa gattttaaat
     2221 attgtatgga tagtggagca acagtagtct ttaacccatc accagaagaa atgtatttaa
     2281 aaggtaattg tactaccatt aatgtttctg gacttacaga ttttctttgt ggagctaaaa
     2341 gacctgttca ttttggaggt gtctgcctag ttgtttcaaa gtttctaaat atagtaacac
     2401 ctgataaagc ttattttgga gagaaggatg cccaacaatt agctgtaatt aaaagaatgg
     2461 tcaaggattt aaacatagat acagaaataa taggctgtcc tataattcgt gaaaatgatg
     2521 gattagcaaa aagttcgaga aatacatatc tctctgagga agaacgaaaa tctgctctaa
     2581 tattaaataa gagcttaagt ttagcaaaag aagaattagt aaaaggcaat ctaaatccag
     2641 agaatataaa agaattaata acagctaaaa taaattctga acacttagca aaaatagact
     2701 atgttgaaat tgtagatagt gagacattac aacctgttaa gcaaatagaa cattctatac
     2761 ttgtggcaat tgctgtgttt ataggaaaaa ccagactaat tgataatttt acatttgagt
     2821 taaatatata gtctataatt ttatataata tatctaaaaa ataatagaat acctaaaaag
     2881 taataaatta cctaaaaaat aataaattgc ttagaaaata atagattaca ataactaaaa
     2941 ttttaaaatt aaattcctta aaagtatgat taattataat tatataagta tattcttatt
     3001 acacttatat taatttatat taaatatcta ctaactcaaa tattcataat taaactttaa
     3061 actggataaa ttttctttta agaatgaaag tttatccagt tttgcgatta taataaccag
     3121 ttttacatat ccacttgtaa aatatatcta agcaatatat catactatat agatttatga
     3181 gtgaaataat atctgctatt tactgaatat ttttattttt cgttttttag ggggattagt
     3241 tgtgtttaaa gataagattg atgaatgtgt tcatataatg actgcatata ttgctagttt
     3301 aaaagaatac tattcattca tagaaactca aattggtgat tttattaaaa aatatggaga
     3361 agatgttgta gagttatgtc tccatagagt gatgattcta ctatgcgaat gtggtttggc
     3421 ataaaattaa atttattaaa atgggtaaga agaatcctat ataatattct tcttacccat
     3481 tttaatatat caatttcata gcttatcgtt taaaatattt tacatccatt actagacaac
     3541 tttacattct ctttttaatt ctagtatatt taaatcattt tagttgctcc ttatttattc
     3601 ttattacttg ttttatttta taaataaaat aattcttttt aataatgttt tttgttgata
     3661 ttcctatcac acatccaatt atttatcatt gtcttgaaat tgtttgcata cttaatttaa
     3721 tccaattgaa acaccccagc atagaatccc ctgtaaaata gaagttggat taaatcctaa
     3781 catctataca gaaaatacta ctccaagcac aagcaatata atggaatata tttatcactt
     3841 aattttttat actttttaaa tcccatacct aaagcattaa gtgcagctat tagaattaat
     3901 aattgttgtg gtataaaatt atgcttgctt catatttatt cattttttac tataaaagtt
     3961 cttgttttac aaaaaacatt tgttttgtat caaaataata cttgtaaatt acataattct
     4021 cataaaaatt tctagtatta cttgtactct taataaataa tagccaacaa gtaccttaaa
     4081 tcattatatc tatatctaat aagaaacaca gtaagataat tttttcgccc ataacttaat
     4141 aaaaactgtt gatattagta gcaattgaat ttagttaatt tatttataat atacataaat
     4201 ttaaatatta cgaataaagt attataaata ggatactttc taaagggagg aaattatgat
     4261 agataatcaa aaatatgtta ttttatcact agaattacat ttattttttt caagaattat
     4321 gaaagagcat gctctttttt tagaagcagg attcacaaat aaaaattata atcttgctat
     4381 ggaagctgac cactataaaa agcaatttga agatttatta tcatacactg ttagtgctag
     4441 taatggtata attagacctg atatattata ttcagaagag cttgtaacta ctctcacatc
     4501 agttgcagaa caaaaaacag aagagtttac agggatagaa ataaacaaaa acatcactac
     4561 aagagaatta aatctacaaa gtggtgtaaa cccacaagtt ggtcaagact tagtgaacta
     4621 tgtagctcaa cttaactctg atgcaataag attacttgat gggcttatta attttaaaga
     4681 aagagtctta gatggtgtac tatcatgtac tatatttaca tcaaactacc ctctacttct
     4741 tgaacatata atacatgaag caaatttata tcgttattat gtagttgacc ttgaaaataa
     4801 aatagatatt gagtcaaaaa acgctaaaga aatagaatta ttctgggacc atattatgat
     4861 ggaacatgct ctgtttatga gaggattact agacccctca gaaggtgaac taataaatac
     4921 ttcaaatgat tttgctataa aatttaatga attaattgaa aaaacaaacg aaatgactga
     4981 ttctaatatc aagaacatta cagaagaaac tctaaatgaa actgttgagt ttaaagattt
     5041 taaagaagca ggagcatcag gaatagaaca gtgtaagata aaatctataa tattaccact
     5101 tttagcagac catgttttaa gagaggcaaa tcattatatt agaatattgg agagttataa
     5161 aaacatgtaa ttaaaaatta cttttaaaat aatctttgca tatttagata aaataaaggt
     5221 acagttaact gtacctttat tttttataaa cttataaaat ttaaacaagt tattcataaa
     5281 ataaaataat aatcatctat aacccacaac tttattttat attaaataaa aagtattagt
     5341 gattatgttt tataggtatt tctttattca gttatttatt aaaaactaat agtaaatctt
     5401 atactaatcg catatttatg ttataactat attgtaacta ttttcgtaat cttaggaaaa
     5461 gattacttat aaaattaacc ttatacaata atatatcgta taatcttaat tagcataata
     5521 gttacaatat taaaatttaa atatgggagt gattttagta tgataagaca aacaccatta
     5581 gagaaacgat atgacaagct aggtcctcat attgtaacag cactcaaaaa acgttatttt
     5641 gatgcttatt actgtaaaac tagaaatgaa gctttgcaac aaattttaga tttaattcct
     5701 caaaatcatg tagtatcatg gggaggatct gaaacactta aagaaatggg cgtacaaact
     5761 gctgttagag agaaaggatt taaagttatt gatagagatt tagcaaaaac tccagaagaa
     5821 agaactgaaa ttatgcgtca agcacttcta tgcgatactt ttttgatgag tagcaatgca
     5881 attagtgaag atggacaact ctttaatatt gatggaaatg gcaatcgtgt agctgcaatg
     5941 atatttggtc caaaaaatgt tatagttgta gctggtatga ataaaattgt aaaaaacatt
     6001 gatgatgcaa tacaaagaac tagaacaatt gcatctccag cagttgttca gcgttttcaa
     6061 gatgtcaata caccatgcta tattaatgga agttgtatag attgcacaag ccctgaaagc
     6121 atttgtgcat acatggttac tacaagaatc agtcgtccag caaaaaaaat aaaggtaata
     6181 ttggtaggag aaaatcttgg tctataaaat atacatacat gtaaatagct ctataaataa
     6241 taaaatcata tgaaataact tatttctaaa agtggtagaa taaaagcttc tacaagactt
     6301 tcattctacc acttttatat tcttttaatt tgtgtttcta tattattaat tgctccgatt
     6361 ttcatatata ttactaacta tttttatttt cataattttt ttgttcttca tcaagctgtt
     6421 tataataatc tttattatag tcagctagat aatctatacc acctcctgta atcacattta
     6481 ataatttcat tgcagattct tgattaactt tacaaacata attatcacca gatttaacaa
     6541 gctctaatgt aatattaaat tcttttttct ttgcagaatc aatatctttc atagttggat
     6601 ttggcatcat ttctcctagt ttaggaggat tcttttttaa aatagaaacc atatcagtat
     6661 tgttaatttt taaatctaca gtcactttat ccttattatt ctttatatct gaaatttccc
     6721 aagtcatatt tttagaatac attttaaatc cttctttatc ttcgtatata agattaccta
     6781 accctgattt tgggaaatac ttatcaacag tatctgcatc ttgtgttttt attgaattaa
     6841 acatactatc cacttcattt tttatcttat tatcattagt acaaccagct aacaccagta
     6901 ctgatattgc aaacattata atacatataa taaatttctt cattaaatta tatcccccta
     6961 tacttttttg cacaaatatt attctctttt ttatcttttg aaaaagttgt agtaattgca
     7021 ttttgtggac aaacttttat acattcacca cacctaatac agtctggact atttacatct
     7081 ttatatattg gtatatcaag cttacatttt gtttgacatg ctgtacaatt tgtacattta
     7141 tctttatcaa ttttaaatct atatattgaa ataggattaa aaaaaccata gattgctcct
     7201 aaagggcata tatacttgca aaatggccta taagtaatga ttgacatcaa taatatcaat
     7261 agcaaaatac ttaacttcca gctaaataaa aatcctattg attctcttaa attctcattt
     7321 cctaaaataa gtagtattcc tcccaaaagt gttcctgaag ggcaaatcca tttacaaaac
     7381 caaggatttc caccccctgc tacatttaca atagcaactg gcaaaataat tacaaacatt
     7441 attaagacta tatactttag atattttaga tatttatcac cataaacttt ttttatcttt
     7501 actggaaagg gtactttatg tagtaaatct tgtacaagtc caaagggaca aagccaacca
     7561 caaacaaatc tgccaaaaaa agcaccaaat gccattaaaa aaccaacaac ataaaatgag
     7621 aatttatact ctctgcttga taaaactgct tgtaatgaac ctattggaca tgctccaagt
     7681 gcacctggac atgaataaca attcaatcca ggtacacata attttttact ttctcctcca
     7741 tatatagttc cttctaaaaa tccatttaca tatccatttg ttaatgctgt aaatgcaact
     7801 tgagtaataa gtcttatatt attatttacc ttagataata acttcatccc tcttctccta
     7861 accaatacca atacactcaa gacaaatcat aattgcttta gttaatactg tatttgtttc
     7921 tccacgatat gtacctaatg caataaatat aatactaatt gcaataatag aaatgccttt
     7981 tttattatct ttaataaagt tactcattgg cttttaccat ttttagtctt tcatctataa
     8041 tttttttcca atcttcctta ctatttgcac ctacaacctt ctcacccaca aagtttcctt
     8101 tcttgtctac aaaataagtt gttggaaact ccataactct tttaaaatca gtttttttaa
     8161 gttcttcaga tacagtcaat tgttggtaag ttgcatctga ctttttcata atgtctttaa
     8221 ctaaattttt ctcttcattt gaaagaccag ttctcatatc agttttatca acttctacaa
     8281 ctaatccctt tatagctaca ttggaattat tactctcata ttcttttgat aatgcttcaa
     8341 gctctggcat ttcacccaca catggtccac accaagtagt ccagacatta ataagagtaa
     8401 gttctttatt tgaaaatatc tcttttgtta ccttatttcc atcaacatcc tccgtatcta
     8461 aattactaaa ccattcacta ttattcttgt ttttttctac tggcttagat tcttttttgc
     8521 tacatccaga aatcatacct aaaacacaaa tacatcctaa aactactatg aaaaaccttt
     8581 tcatatctca cactcctaga atttatatag tatataaaat cgctgcttga aataaaaata
     8641 acttatcttc tatattaaag taattatatt taataaataa gagctaattt aaaaaaagat
     8701 atacagttaa aatctatttc ttttcagaca aaatcttata tatatataat agcttgtaaa
     8761 tcttaagatt atatacatat atttctaaag attttcttaa gaaacagtta gattttacta
     8821 atataagttt attaattagc attatactaa tttatcttaa tatgattttt tgttgatttt
     8881 aagctgttta tcgtataaat aaaatttttc ttgactatat agttactata tagcttatta
     8941 tatatagaga gtaataaaag gaggtaaaat ttatggaaaa tttatttaca agaaaattca
     9001 ctacttttga atttctaaaa tttgtttctc ctgcaattat atccatgata tttatatctt
     9061 tgtatacaat aatagatggc atctttgtat cgacattagt tggttctgat gctcttgcta
     9121 gtataaatat tgtactacct ataattaacc ttgtttgtgg atttggaata atgatggcaa
     9181 ctggtggagg tgctatcgtt tctatacgta tgggtgaaaa tagacaggat gaagccaact
     9241 ctacattttc ttttatagtt ttgttttcat tgattgttgg gattttattc acagtaatct
     9301 catatttctt tatcaaagaa atatctattt tgcttggtgc aacagataag ttattaccat
     9361 attgtataac ttatggtaaa gttatgattt tatgtacacc attttatatt ttaaaattta
     9421 tatttgagta ctttgcaaga actgatggaa attctaaatt tagtttattt ctatcagtca
     9481 ttggtggtgt aacaaatata atattggatt atgtatttat taaatatttt ggaatgggtc
     9541 ttttaggagc tgcagttgca actgctatag gtattatttt aacttgtgtt ttaggtatta
     9601 tttacttctt atctaataaa tctacactaa aattaagaaa accaaaaacc gattttagac
     9661 ttataagaga tactatgata aacggttctt ctgaaatggt tacagaatta tctacaggaa
     9721 ttacaacatt cttatttaat gtagtagctt taaaattagc aggagaaaat ggacttgctg
     9781 ctcttactat agtattgtat gctcattttt taatgacatc agtctatcta ggattcgctg
     9841 ctggagtgtc tccattaata agctataatt ttggtgctga aaacagtgat aaattaaaag
     9901 aaacatttaa acattctcta aaatttatat ttatttcttc tcttttagtg tttattattg
     9961 ctttagtatt tgcaccattt attgttaggg tctttgtaaa tccagataac acagtattta
    10021 aactagcctt acaaggatta aaaatatttg catttgcttt tttgtttgtt ggtataaata
    10081 tatttgcatc aggatttttt acagcatttc acaatggaaa aatttcagct attatatctt
    10141 ttagtcgtgc ctttgttttt ataatcatag gaatcataat tcttcctcct atgttaaaca
    10201 tgactggatt atggcttaca gttccatttg ctgaggttat aaccatattt atatctattc
    10261 tatttataaa aaaatataaa tgtagatata agtattaaaa attaatactt aaaatcaaca
    10321 tttattaaaa ctaataaacc tgctttaaaa tacaaattta caaatttgat ttttaagcag
    10381 gttttatttt agttataata agtcatttgc atactcttta attggtgctt ttctaagtaa
    10441 taaaattata aatattatgc aaataactat aattcctacc tttgttccaa ataaaataaa
    10501 aggattctga aatgaataaa taattttttc taaatacaat agcattttat gcatattttt
    10561 agttgcaaaa ttaactatat aaattaccat taatatcggt aatcctatca atatagtaat
    10621 actagtaact tttctaactc tatatgtaaa agctccaagt aacactccta taaaacctat
    10681 acatatttca tttatacata tttgtacaaa ataatttaaa taagttagtg gcatacttga
    10741 tgttgaagga tctatcagtg ctgatataga tgtccaaatc atatctctct ttagtaaaac
    10801 tgatagttct atactgtaac ctgttataat ttctataaat aacttcgata aaaaaatcaa
    10861 aactatacct aaaatagaaa tcacaaagct taaaataatt aaatctatga caatagcttt
    10921 tatacaactt tttctatctg ctcttatact taaagctcct gaaaagtctt tatttgctat
    10981 atttactcca tacacaaata gcagtatagt tatatatgtt aaaataggat tcacaatcgt
    11041 ggataaatta gttttagatg cttctccaaa aatcttgaga ataaacactg gcaaaatatt
    11101 cataacaatt cccacaatca taaatataat tatatacaat ttagtatttt tattaaaaaa
    11161 ttttatatat ggctttaatt cattcaatta caattcctcc ttcttagtca tgttaacaaa
    11221 catatcttgt agccctatgt atcctacatc aatatttgaa tttttaagta ttttttcatc
    11281 attttcacta aaatcaccat agtaaaaata agcaactgca tttccaaatg cctttttagg
    11341 ttttatattt tttatacatt ctaatttttc taactcttct ttatttccag taatataatg
    11401 agctttttgt tttatgacat caatttcttc atctataata atttttccct catttaatat
    11461 tattacatgc tccagtaaat catctatttc atcaatcaaa tgagttgata ttattattgt
    11521 ccttggattt tttatataac tatctaaaat tatgttataa aactcttgtc tatttactgc
    11581 atccaaacca attgttggct catcaaatat ggtgatagct gaattagaac aaatacctat
    11641 tatatttgaa agtatagttt tcatacctct tgacagttgt ttatactttt ttttagtatt
    11701 taaatcaaaa tatttgcata attctttttc taagccttta tcataacttt tataaaaact
    11761 agaagaaaat tcaaatatct gacctacttt aaaatctgga ctataaaatt ctttttccct
    11821 gacaatacaa acttcttcca aaacttttat atcttctttt gggttctttc ctaatatttc
    11881 tatctcacct tcattttgaa ttaactgatt taccattata tttaataatg ttgtttttcc
    11941 agctccattc ttacctaata aaccatatat cttatttttt tcaaagttta gagacatatt
    12001 attaaaaata ttttgcttct taaaactgtg agataaattt tctatcttaa tagaactact
    12061 catatattaa tcctccttga aattaattat aatatcaacc aattcttctc tatttatttc
    12121 taatttgtta gcttcttgaa gtaggttttt tacaaaatta tgtttaaaat tttcttttct
    12181 agcttctttt ataatagttt ttgcaccatc tgatacaaac atccctatcc ccctcttctt
    12241 atataaaata tttttatcaa ccaatatatt tatacctttt aatactgtag ctggattaat
    12301 tttataaagc tttgaaagct ctgttgttga tggaacctgt tcttcttctt ttattccatt
    12361 tgatagtatc tcatcttcaa ttgctcgtgc tatctgaata aatataggtt cttcattatt
    12421 taatactaat ttcataggtt cctcctttct ccattagtta gttactcaac taattaacta
    12481 tataacttat aatatcttga aaaatatttt ctgtcaatac taaataaaaa acagagggaa
    12541 aattccctct gttttttgtt ctttatattt ataattaaat tttgattttt gtaatcctat
    12601 cccataagtt aaaaacttta ataatctgtt gtatcttcat tttttaatat tttacatatt
    12661 gagctagttc ctaacctttc tgctcctgcc tctataaatt tttctgcatc agaaattgat
    12721 ttaactcccc ctgcagcttt tatttttaca ttttttccaa catgctcttt cataagcttt
    12781 atatcttcta aagtagctcc acctgttccc attccagtag atgtttttat aaaatctgaa
    12841 cctgacattg ttactatttc acacattttt attttttcat cttcatctaa ataacatgtc
    12901 tctataatga cttttaatac tttatctcct atagcttttt ttatttcttt tatttctttt
    12961 cctatattat cataatcttt attttttata tctgaaatgt ttacaaccat atcaacttca
    13021 tctgctccat tttcaatagc atcttttgct tcaaatactt ttgtagcagt agtttgatat
    13081 cccaaaggga accctatcac tgtacatatc tttattttac cttttagata ttctgatgct
    13141 cttttcacat atgatggtgg tatgcaaact gatgctacac tcatatctac agcttcatca
    13201 cataaaattt taatatcttc ccatgtagtt gtagctttta aaatagtatg gtctactgtt
    13261 tttaatatat gtttcataaa atcctcctaa atttataatt aatataatta gattactttt
    13321 ttaaatgcaa ttttctcttt gcaatattca gtatcatatc aacctcttca actttaaaaa
    13381 tagtcattag tagtgtataa attccacctc caactataac tgaaatagct agtgagacaa
    13441 actcattaaa tgttcctact cccaaaattc caaatataaa tttatacgta aagtatgata
    13501 aaacacccat aattaaagat gcaactaccg atttcaaagt tgcttttatt attttatctt
    13561 gtccaaaata tccaactttt ctctttaggt tcaagaagag taacaatata catgcaattg
    13621 atgatgaact agttgcaaga gcaagaccac catgagccat tggttttatt aaaactaagt
    13681 ccaatactat atttacccct acagatataa tcccatttac cataggtgtt tttgtgtctt
    13741 gtaatgaata aaaaaccttt cccaaaatat ctcttaagcc aaatgcagtc ataccaactg
    13801 cataaaaaat taaggcagtt gctgtcattt gggttgccct cgcatcaaaa gcacctctct
    13861 caaaaatgat tctaacaaca ggagttgcaa aaaaaataga agcaactgaa ataggaatca
    13921 tagaaattat tatcatattt atactagatt taactgaact agtaaacttc ttttgattat
    13981 tttctgcact taacttagat aacataggat acataacaga tactattgaa gctgtaaatg
    14041 tccctgtaac aaaaccattt aatctatctg cataagtaag tgctggaatg cttcctttaa
    14101 ctaatgttga ggctaaagtt gtatctacca atgagttcac ttgattaaca gcaacaccta
    14161 taaatactgg tgaaagtaat gctagtaatt taataaggct atcatcttta aagtttaagt
    14221 agtataagta tttgtagttc gtttttttaa caaaaaacat gtaaaagagc agttgaacta
    14281 ccatagcaac cacagcacca attggaagta tgtatggtcc aaatatggta cttaacatta
    14341 ttgaaataat tattactata ttatagggta tacttccaaa tccaactaca ataaagttct
    14401 ctttaatttg taaaaatgct gacataacac ttgtaatacc tatgaatatt attcctgttc
    14461 tgaacctccc atgactaaag tcacagggtt cctgcttcat agaattttgc atactaaaat
    14521 atgtcttact aattctccac aggctatccc cgtagttcct acggttctta catacgttat
    14581 ttattttgaa ttgttattag tcttaatcct tcttttaata tatttctact tgcatttata
    14641 tctctatcgt gagtttcatt acaactagga caaatccatt ctcttatatt taagttctta
    14701 acttcctcgt ttttataccc acatttattg catatttgtg aacttgcaaa gaatttacct
    14761 acctttacaa tttgtctacc atgccaatta gccttgtatt ctaattgacg aataaactct
    14821 gaccatgata catcagaaat taagcgagat agtttatgat ttttaatcat attctttact
    14881 tgtaaatctt ctatgcaaat aatatcattc tcttttatta atttagtagt taatttttgt
    14941 agaaaatcat ttctttgatt agctatatgt tcttgaagtc ttgcaacttt taatcttgct
    15001 ttatttctat ttaaactacc gattgttttt ctcgataatt ctctttgtaa tttagcaagt
    15061 ttgtttaatg acttcttaaa atacttagga ttttctataa attctccaca acttgagata
    15121 caaaattctt taattcctaa atctaaacct atctgattgt tagt
//
LOCUS       DAEPHU010000091        14898 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 01A10CD0081
            SAMN05941466-rid12468953.denovo.091, whole genome shotgun sequence.
ACCESSION   DAEPHU010000091 DAEPHU010000000
VERSION     DAEPHU010000091.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941466
            Sequence Read Archive: SRR6291087
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 14898)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14898)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068158.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 22:43:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,892
            CDSs (total)                      :: 3,805
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 87
            rRNAs                             :: 8, 1, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 55
            CDSs (without protein)            :: 55
            Pseudo Genes (ambiguous residues) :: 0 of 55
            Pseudo Genes (frameshifted)       :: 21 of 55
            Pseudo Genes (incomplete)         :: 28 of 55
            Pseudo Genes (internal stop)      :: 16 of 55
            Pseudo Genes (multiple problems)  :: 8 of 55
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14898
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941466-rid12468953.denovo.091"
                     /strain="01A10CD0081"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            complement(473..619)
                     /locus_tag="KR231_003221"
     CDS             complement(473..619)
                     /locus_tag="KR231_003221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0005562.1"
                     /translation="MVFETFDKTIELYPNAKPIFHSDIGFRLDDESFEEYLGRVFRKR
                     CKGI"
     gene            715..1364
                     /locus_tag="KR231_003222"
                     /pseudo
     CDS             715..1364
                     /locus_tag="KR231_003222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429361.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase family
                     protein"
     gene            1905..3260
                     /locus_tag="KR231_003223"
     CDS             1905..3260
                     /locus_tag="KR231_003223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HBH0005563.1"
                     /translation="MDTKISINENMSLGKRFFKYLAPSVVAMWVFSLYTMVDGIFVSK
                     GVGELALAAVNISMPFINFIFAVSLLFSTGASTIIAIYLGKKDIKSANEVFSFNLVSI
                     IILSIIILAITFFNLDRLALFLGATESTIGMVKDYLGIIIFFNGFFIVSYSLEVIIKT
                     DGFPILATVGVIISALTNIILDYLFVIEFGWGVKGAGIATGLSQVFSTIFFLIHFLRK
                     NSTLNFSKFRIDFKTLRKIVFIGFPDSTTELSCGIVVLLFNLSLTKYIGENALIYYSV
                     INYINTLVLMTMMGITQGMQPLTSFYYGAGNIDNVKKLLKMGIKATIIASVAVFAICM
                     AFSGPIVSLFIHPEETMLFNEGVRVFKIFSISFLLVGINVIISGFFVSVEKPSISTVI
                     SLGRGLVIVVLSLISMILIFGGQGIWMTTIVSEFICLILSLVFLKKNFSTLDSNLNKV
                     A"
     gene            complement(3378..4046)
                     /locus_tag="KR231_003224"
     CDS             complement(3378..4046)
                     /locus_tag="KR231_003224"
                     /EC_number="6.3.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diphthine--ammonia ligase"
                     /protein_id="HBH0005564.1"
                     /translation="MKEVLKLADEKFVMSFSGGKDSILALNRMLKKGYKPVALLTTIS
                     EEHGKSWTHNLEYNMLKQVSSNIGLPLLVAECGVEGYEESFERALIKAKNMGATICAY
                     GDIDIESHRKWDTDRCEAVGMKVDLPLWQESREDLVYEFIDSGFCSVVTKVNLKHLGE
                     EFLGKKLTRELVEKIKNAGADPCGEHGEYHTFVVDGPIFKKPVEYEVKGTLIKDGYGY
                     LEIK"
     gene            complement(4113..4541)
                     /locus_tag="KR231_003225"
     CDS             complement(4113..4541)
                     /locus_tag="KR231_003225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DMT family transporter"
                     /protein_id="HBH0005565.1"
                     /translation="MTKLWAIIFALLAGGSTALEAFINGELGKSTTALVATFISLTVG
                     AIFFLASIIVTGDLKCLVSINGFNYKLLLGGVFGGLIIYFTVKAIPNLGVSNTLILTL
                     VSQVLVGFFIDSVILGQETMHLYKYIGVILLILGTFFIVN"
     gene            4648..5241
                     /locus_tag="KR231_003226"
     CDS             4648..5241
                     /locus_tag="KR231_003226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF308 domain-containing protein"
                     /protein_id="HBH0005566.1"
                     /translation="MNFCYNCSIDFGGDFMYTNFNIDFNNFNKKENAIKFMLMGVLLI
                     ILGLLCLTFKTLGIKLISWTFGIALLFFAYLNLKNINELKRYATKEEIKPSINIQWVL
                     IIACILLFVFPQKIQSIFSLFLGFYLIFNQLVALVNSKNNPYSKFTTWNIVKILFGIC
                     LILSPLFLSRFIVSIMSFFIILFGLVLFFSGNTARKY"
     gene            5360..6295
                     /locus_tag="KR231_003227"
     CDS             5360..6295
                     /locus_tag="KR231_003227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893027.1"
                     /note="This family includes YhcC from E. coli K-12, an
                     uncharacterized radical SAM protein; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01212 family radical SAM protein"
                     /protein_id="HBH0005567.1"
                     /translation="MDKFKYAFDNKRYHTWNYYLRNTFGEKVFKVSINAGFTCPNIDG
                     SLGYGGCTYCSKEGSGDFAGNPKDNLISQFYNIKEMMLKKWPHAKYIGYFQAYTNTYA
                     PLEVLKEKYETILELEDVIGLSISTRPDCLPDDVVEYLSELNKRTNLWVELGLQTIHD
                     STSKIINRGHDYKTFVEGVEKLKSKNIKVVVHIINGLPGEDYNMMMETAKAVGKMGVD
                     GIKIHLLHVIKDTPMEKMLQNGMLTLMEQDEYINLVCDQLEILPETMIIHRLTGDGKR
                     DELVGPIWSLKKWEILNQIDDTLKARNSYQGCKFV"
     gene            complement(6566..7510)
                     /locus_tag="KR231_003228"
     CDS             complement(6566..7510)
                     /locus_tag="KR231_003228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EamA family transporter"
                     /protein_id="HBH0005568.1"
                     /translation="MGEKSKGYVFIAIAGLLWATLGLFGKFLMGNGLTSEQVAFTRLF
                     FGFIVLGVYSSIRTPQILKISKKGIIYSVIIGIICQAMFNLCYFKAIDIAGVSIAAVL
                     LYTSPLFLAIFSKICYKENITRSKLFSLILCFIGAIMAVTGGRLDFQGLNAFGLLLGV
                     LSAIAYALMPTISKNALKEFSSSTILVYSFLFGAIFMIPSSRPWEILNYAKDLDVLSC
                     MLMLGIVPAALAYIFYAAGISKGVELSVAGVVASVELVGSVIIGCTILGESFSLGKLF
                     GVMLMLISAVVALNLSYDEIRIFYKSNKLKQIEKTESI"
     gene            7828..9258
                     /locus_tag="KR231_003229"
     CDS             7828..9258
                     /locus_tag="KR231_003229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HBH0005569.1"
                     /translation="MNLDLEFYQKILEASHDEICVSDDKGIIIYCNKAFEENYGLKKE
                     DILGKNVSFLEDSGYSTKSPIPIVLKTKTKFSLEQDTQTGKKLIITATPIFDENGNLE
                     FTVENCRDITELNNIKNKLEDTKKQVKKYKSEVETLYRTALRIEDTVIMDGIVMRPII
                     NTVNHVSKTDVSVLLLGESGTGKSSLARYIHHNSNRSNGPFITINCATISPQLLESEL
                     FGYTSGAFTGASTKGKVGLVELANGGTLFLDEIGDIPQNLQAKFLQLIQDRTFTPVGS
                     LKNKKVDIRIISATNVDLVSKVKEKKFREDLYYRLNVIEIKLPPLRERRDNLVEIIKY
                     YFNRYSSDFNLNKTISKEAMDAIANYRFPGNIRELQNIIQKILLTCTDNHITIDDLPN
                     ILTKNIHITNNGNKTHISQINKVIISDSKSTNYKNKNFDTLIKEYEKNIILDAYEKFG
                     SSYKVAKHLEISQSKANRLIRKYTNT"
     gene            9458..10042
                     /locus_tag="KR231_003230"
     CDS             9458..10042
                     /locus_tag="KR231_003230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc dependent phospholipase C family protein"
                     /protein_id="HBH0005570.1"
                     /translation="MLMNTHFIMAKSILDNIDENKTFFISEKNFIYGNIKPDAFSKYK
                     LKKHYLDESFNMIVSKINYLCSLNIDSLSKYFSVSRLSQELGVICHFLCDFFCVAHSE
                     RWEFKHSLNKHVTYERELGAFAKDVDLSKIKCGTINSSFEKFFTKLYSDYKKKTDYMN
                     DLKFSAYTCNSVINYILDSILSNTIKSYHIANCG"
     gene            complement(10146..10925)
                     /locus_tag="KR231_003231"
     CDS             complement(10146..10925)
                     /locus_tag="KR231_003231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HBH0005571.1"
                     /translation="MIKHIFCDLDGTLYENGTITKEDIVAIEEIEKKGVQFNVATGRI
                     FKQAHNIIKDSLDMNGYYVCENGSFIYDKDYNVIFKRTIDDNLVKKVIDRFESSDAQL
                     YFKYKGDVIVGSDTTAFRHYSSDFIVDPDFEKRSSFDNLIGNIGVCSENLEELSRIEL
                     YLKSEFSEVLEIYFSGTYTLNIVPKSVSKRGSIEHVIKTLNVSPDEVATIGDSPNDIC
                     MLEGFKYSFAMSKAREDVKQSANYVVDSVKSAIDVIMEINS"
     gene            complement(10983..12239)
                     /locus_tag="KR231_003232"
     CDS             complement(10983..12239)
                     /locus_tag="KR231_003232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011591286.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence/damage-inducible protein A"
                     /protein_id="HBH0005572.1"
                     /translation="MKAEIISVGTEILLGDIVNTNSQFLAKELASLGIEVYHQSTVGD
                     NKQRLLECFDESLKRSDFVITTGGLGPTGDDMTKETAAEYFGQKLELHKPSLEVLESF
                     FVKTGKKMAENNMKQVYFPKDAIVLKNNNGTAPGAILKKDGKFIIVLPGPPREMKAMF
                     NESVKPYLQQFTNEMLVSKTLRLYGIGESNLELEILDIINEQTNPTVALYAKELEVTI
                     RITAKAENEREAFKLIKPVEEKIKSRVGKYVYTEGDISISEGETALEDAVSKLLVEKN
                     LTIAVAESCTGGLVSSSLINYPGISSVFLEGCVTYSNDSKMKRLGVKRETLEEFGAVS
                     EQTAIEMAEGVAKGLKANIGISTTGVAGPGGGTKEKPVGLVYTAIYINGKTIVKKNIF
                     NGDRRKIRLRATRDLLNELRIQLEKL"
     gene            12497..13396
                     /locus_tag="KR231_003233"
     CDS             12497..13396
                     /locus_tag="KR231_003233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--D-alanine ligase"
                     /protein_id="HBH0005573.1"
                     /translation="MKIAVIMGGISSEREVSLNSGKEIYNNLDKNKYEVVKVIIDDKK
                     DIFTKIPEDIDFAILALHGKFGEDGCIQSILETMDIPYSGCGPLCSGMCMDKNITKKM
                     LRDSNLPTAPWVLVKSVDEIDYDEIDNIGYPVFIKPNSGGSSVATFFIHSKDEVEEAV
                     RKGLEVDEFVMIEKYIPGGEYTSFILNGEVFPTISIKSDSGFFDYEAKYSVEKGAKEE
                     VVYLDEELQKRVNEISETCWKIFNCKAYVRVDMIISEGIPYVLELNTLPGMTQTSLIP
                     RSAAARGIKYSELLDKLIEYSLN"
     gene            13420..14868
                     /gene="ddlR"
                     /locus_tag="KR231_003234"
     CDS             13420..14868
                     /gene="ddlR"
                     /locus_tag="KR231_003234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902483.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator DdlR"
                     /protein_id="HBH0005574.1"
                     /translation="MIFSNLKLNDNEPIYIQLKNYISDMISKGLIPDNSKLPSTRELS
                     QLLQVSRNSVVLTYEELKSEGLIYSISGKGTFVKSKNKSSNTTWSLNWDCLENTYSKK
                     ANELDIIKSEIPWSSDLISFKSISPDGDLFDIEELKKSFLNRISLEGHKLLNYGYAQG
                     YKPLIDYLLEYMTNKGADISNKDILITNGFTEGFDIIMSSFTQEKDYIICENPTHNTA
                     IKIMKSHNLNILGVDINEDGLDFNMLEDNLVKYKNKIKFAYITPSYHNPTGIVMTPEN
                     RYKFYNLMKKYNIAIIEDGFNEELLYNSSHIFPICSLDNMNNGVVYIGSFSKILFPGM
                     RIGWIFADKKVINKLESVKRCRNIHVSFLDQGILFDYLSNGGFEKYIKKIRKFYGDKF
                     NFAYKCIKKYIKTEYILGDGGLHIFIKLKNIDTRVLLEKCYEKNVIFMPGDLFFTDNS
                     GFDTLRLGFSRLSFEDIEIGIKIIGETINEMF"
BASE COUNT         5466 a         2119 c         1876 g         5437 t
ORIGIN      
        1 taaaactata caacaaagat aatatttagt aaaaataact ttcattttaa ctaaacttaa
       61 aattcaatta ctctctaaat tgacgtttag gaattagttc aaaataaaaa agagtgtata
      121 tattgaaatt actacatttc aatatataca ctctttttaa atttctcagt tttccatgga
      181 actttacttt atttatttct gtattagttg tattttttat gcatttttct ttaaaatcat
      241 attttctgat tcaactctta tattataaaa tttctttact aaattattct ctttttctat
      301 atcttcatat atatttttta atcgcctttt acctaatctt ttatctaaca ttactaatga
      361 tttaactaat atattatatg attttatcgc atcttctatt gagatattta aacatatatt
      421 tactgcttca taaaaatcaa attcattaaa aaatccattt ttatttacaa tcttatatcc
      481 ctttgcatct ctttctaaat actcttccta aatactcttc aaaactttca tcatctaatc
      541 taaatcctat atcactatga aaaataggtt ttgcatttgg atatagttct attgttttat
      601 caaaagtttc gaataccaag ttattattat tcgattttcc aacagtccac tataaacaat
      661 aataagtttg ttgctccaaa taatgtaaca cttgtagaaa gatgttacag atatataaaa
      721 gatagagaat gtagtttttc tcctaatact attagaaata gaaaaaatat gattaaaaat
      781 caaattgaag ttttctttaa agatatgaaa ttaatagata taactccttc tattttacag
      841 tcttatataa ataacatata caatgagcac atgttaaatt caacaaaaaa ccaagtcgat
      901 tttataaaat cagtattgaa agaatcttat agattaaaag aaatatcaga aaatatttgt
      961 gattttgtta caaccccaat caaaaaaaat agttcaactt ctaagcttta tacaaaacaa
     1021 aaagctcaat tattattaga aaaatcaaaa aatattccta taggtatacc aatttttttg
     1081 atgctaactc ttggattacg ttttggtgaa gctgtatcac ttatatggtc agatgtagac
     1141 cttgataaaa aatctcacat gtaaatcaaa cattagttta tgtatacaat aaaataatct
     1201 tcaaaggccc taaaacccct agattcaaaa gaagattatt tgttcctgat gaacttataa
     1261 gtttgtttaa aggggaaaaa ttaaaacaaa ataagttaaa attacagggt atattgaaaa
     1321 atgaatttga tttgatatgc ttaaataaaa gattcaaccc gtgagttcaa ccaacttttg
     1381 ttgttcattt taaaaaacta ttaagagata ataatcctag agatataaaa gtacatgaat
     1441 taatacatgc aaatgcgact ttgatattac tttcaggtac taacataaaa gctatttata
     1501 aaatattagt acatgcagat ataaaaatag ctatgaatat atattccata ttctcactta
     1561 ttagatgaaa tgaataaaga aacatctgaa aatataagca aaatactatt caaataatgt
     1621 tcagttttat gtcaattaaa tgtcactcaa agtgcttttt ttccatttgt cagttaaatg
     1681 tcacttaaag tacctttttc ctatttgtca gttaaatgtc agtaatatat aaataagata
     1741 tatttataag acccttaaaa tcactattat ttaataaaat ttataattat atactatttg
     1801 ctgttgacat tggtattata ccatagttta tcatttatat tagaataaaa ttattaatta
     1861 atagtttcgt aattttataa tagatttaca gggagtgata ataaatggat acaaaaatat
     1921 ctataaacga aaacatgagt ctaggtaaaa gattttttaa atacctagca ccatctgtag
     1981 ttgcaatgtg ggttttctca ctatatacaa tggttgatgg aatatttgta agtaaaggag
     2041 ttggagaatt agctttagct gctgtcaata tatcaatgcc ttttattaat tttatatttg
     2101 cagtttctct attattttca actggtgcat ctaccataat tgcaatctat ctggggaaaa
     2161 aagatattaa atctgctaac gaagtctttt catttaactt agtatcaata attatattat
     2221 caataattat attagctata acttttttta atttagatag attagcacta tttttaggag
     2281 ctacagaatc tacaattggt atggttaaag attatttagg aataataata ttttttaacg
     2341 gattctttat agtgtcttat tctttagaag ttataataaa aactgatggc tttccaatat
     2401 tagctactgt tggtgtaata atatctgctc ttacaaacat catacttgat tacttgtttg
     2461 taattgaatt tggatggggt gtaaaaggtg ctggtattgc aactggtttg tctcaagtct
     2521 tttctactat tttcttctta atacattttt taagaaaaaa ctctactttg aatttttcaa
     2581 aatttagaat tgattttaag acacttagaa aaattgtatt tataggtttt cctgattcaa
     2641 ctactgaatt aagttgtggt atagttgttt tactttttaa cttaagtctt actaaatata
     2701 ttggagaaaa tgctcttatt tattatagtg tcataaatta tataaataca ttagtactta
     2761 tgactatgat gggtataact caaggtatgc aaccacttac tagcttttat tatggtgcag
     2821 gaaatataga taatgtaaaa aaattattaa aaatggggat aaaagccaca ataatagcat
     2881 cagttgctgt atttgcaatt tgtatggctt tttcaggacc aatagtctct ttatttatac
     2941 atccagaaga aacaatgcta ttcaatgaag gagttcgtgt atttaaaata ttctctatat
     3001 ctttcttatt ggtaggaatt aatgtaataa tttctggatt ctttgtatca gtagaaaaac
     3061 catcaatttc tactgttata tctcttggta gagggcttgt aatagttgtt ttaagtctaa
     3121 tttcaatgat actaatattt ggtggacaag gaatatggat gactactatt gtttctgagt
     3181 ttatatgtct tattttatca ttagtttttc taaaaaagaa tttttctaca ttagactcta
     3241 atctaaataa ggttgcttag atgataagag tgacaatata tgaaaatatc taaataaaaa
     3301 atacctatta tacaatcttg caaatattaa acctttgcaa aaattaggat tatataatag
     3361 gtattttatt tatgtaatta ttttatttct aaatatccat agccatcttt tattaaagtt
     3421 ccttttactt catattctac aggtttttta aatattggac catctacgac aaatgtatga
     3481 tactctccat gttctccaca tgggtctgca ccagcatttt ttatcttctc cacaagttct
     3541 ctagttaatt tttttcctaa aaattcctct cctaagtgct ttaagtttac ttttgttaca
     3601 acactacaaa atccactgtc tataaattca tatactaaat cctctctact ctcttgccat
     3661 aatggtaaat ctactttcat accaactgct tcacatctat cagtatccca ttttctatga
     3721 ctttctatat ctatatctcc atatgcacat atcgttgctc ccatgttttt agcttttatt
     3781 aaagccctct caaagctctc ttcatatcct tctacgccac actcagcaac taataaaggt
     3841 aatcctatgt tgctacttac ttgcttaagc atattatatt ctaaattatg tgtccatgac
     3901 tttccatgtt cttcacttat agttgtcaag agtgccacag gcttatatcc ttttttcaac
     3961 attcgattta atgctaatat actatcctta ccaccactaa atgacattac aaatttttca
     4021 tcagccaatt ttaacacctc tttcatctaa ctttgtttta ttaacataat tataccaaat
     4081 ttttgagttg catagcaaat tatattaaat tgttaattca ctataaagaa tgtccctaat
     4141 attaaaagta taacccctat gtatttgtat aaatgcattg tttcttgtcc caaaattacg
     4201 ctatcaataa aaaatccaac taaaacttgg gatacaagag ttaatataag tgtatttgat
     4261 actcctaaat ttggaattgc ctttactgta aaatatatta ttagacctcc aaatactcct
     4321 cctaataaca acttataatt aaaaccattt atagatacta gacactttaa gtcacctgta
     4381 actattatac ttgccaaaaa aaatattgct cctacagtta agcttataaa ggtggccact
     4441 aatgctgttg tactttttcc tagctctcca tttataaaag cttcaagagc tgtagaacca
     4501 cctgctaata atgcaaatat tattgcccat aattttgtca tggacaaacc tccttctata
     4561 taattctatt aatagaagtt tatgatacaa cctattaatt aattactaag tatagtttaa
     4621 tttttataca ctaggcttta tttggatatg aatttctgtt ataattgttc tatcgatttt
     4681 ggaggtgatt ttatgtacac aaattttaat atcgatttta ataactttaa taaaaaagaa
     4741 aatgctatta aatttatgtt aatgggagta ttactcatta tattaggatt attatgcctt
     4801 acatttaaga cattaggtat aaaattaatt tcttggactt ttggtattgc acttttattc
     4861 tttgcatatt taaatttaaa aaatattaat gagttaaaaa gatatgctac taaagaagaa
     4921 attaaaccct ctattaatat ccaatgggtt ctaataattg catgtatatt actttttgta
     4981 tttcctcaaa aaatacaaag catattttca ttatttttag gattttattt aatctttaat
     5041 caactagtag cacttgtaaa tagtaagaat aatccttatt ctaaatttac aacttggaat
     5101 atagttaaga ttctatttgg tatatgcctt atattatctc cacttttttt atctagattt
     5161 atagtatcga taatgtcttt tttcataata ttatttggac tagttctatt tttctctgga
     5221 aatacagcga gaaaatatta attattttct cgctgtattt ttatattact taaaatagaa
     5281 tttgtttaag ttatctattt gtggtaatat gttttttgta caagctcagc gtacaatttt
     5341 attagaaata ggtgattttt tggataaatt taaatatgct tttgataata aaagatatca
     5401 tacttggaat tactatctta gaaatacttt tggagaaaaa gtttttaagg tatctataaa
     5461 tgcaggattt acttgcccaa acattgatgg aagtcttggt tatggcggat gtacctattg
     5521 tagcaaagaa ggctcaggtg attttgctgg aaaccctaaa gataatctta tcagtcaatt
     5581 ttataatata aaagaaatga tgttaaaaaa atggcctcat gcaaagtata ttggctactt
     5641 tcaagcctat acaaatacgt atgctcctct tgaagtttta aaagaaaaat atgagactat
     5701 attagaactt gaagatgtca taggtctttc aatatccaca agacctgact gtttgccaga
     5761 tgatgttgta gaatacttat ctgaactaaa taaaagaacc aatttatggg ttgaacttgg
     5821 acttcaaaca attcatgatt ctacatctaa aattataaat agaggtcatg attataaaac
     5881 atttgttgaa ggtgttgaaa aactaaagtc taaaaatata aaggttgtcg tacacattat
     5941 aaatggtctt cctggtgaag attataatat gatgatggaa acagcaaagg cagttggtaa
     6001 aatgggtgta gacggtataa aaatccatct attgcatgtt ataaaagata ctcctatgga
     6061 aaagatgtta caaaatggta tgttaactct tatggaacaa gatgaatata tcaatcttgt
     6121 ctgtgaccaa ttagaaatac ttcctgaaac tatgataatc catagactca ctggtgatgg
     6181 taagagggat gaactagtag gtcctatatg gagcctaaaa aaatgggaaa ttttaaatca
     6241 aattgatgat actttaaagg ctagaaattc ttatcagggc tgtaagtttg tttaatacaa
     6301 aataataact atagaaatgg ttatataaat atagtccttt ctatagttat ttagtattta
     6361 caaaacaaaa tattaatttg tacatttata caatatataa taaaaaatag atagtctaaa
     6421 ctgtatctac ttatatttta tttgtactgt ccactttatt ctataaaatt tataaatagt
     6481 tattttttaa taccaaatat aatttggtat aatttttgtt ggactctaaa atgtatacca
     6541 ataaatcctt tttaagtata taattctaaa tactttcagt tttttcaatc tgctttaact
     6601 tgttggactt ataaaatatt cttatttcat cataagaaag attaagtgct actactgcag
     6661 atattaacat caacatcact ccaaataact tccctaagga aaaactttct cctaatatag
     6721 tgcaaccaat tattactgaa ccaactaatt ctactgatgc cacaacacct gcaactgaca
     6781 actctacacc tttagatata cctgctgcat aaaaaatata tgcaagtgca gctggaacaa
     6841 tgcctaacat tagcatacaa gataaaacat ctaaatcctt agcataattt aagatttccc
     6901 aaggtcttga agaaggaatc ataaatatag ctccaaataa gaaactgtat actaatattg
     6961 ttgaacttga aaattccttt aaagcatttt tactaatagt tggcataagt gcatatgcta
     7021 ttgctgataa taccccaagt aaaagtccaa aagcgtttaa accttgaaaa tccaaacgtc
     7081 caccagtcac tgccataatt gcaccaataa aacaaagaat aagtgaaaat aatttgcttc
     7141 tagtaatatt ttctttataa catatttttg aaaatattgc taaaaacagt ggtgatgtat
     7201 atagtaaaac tgctgcaatt gatacacccg caatgtcaat tgctttaaaa taacataaat
     7261 taaacattgc ctgacatata atacctatta ttactgaata tataattcct tttttgctta
     7321 tctttaagat ttgtggtgtc cttatagatg aatatacgcc taaaactata aatccaaaaa
     7381 acaatcttgt aaatgctact tgttctgatg tcagtccatt tcccattaaa aactttccaa
     7441 ataatccaag tgtagcccat aataaccctg ctattgctat aaatacatac cctttacttt
     7501 tttctcccat tttaaattcc cttctatttt tatttagtca atttacactc ttctttttaa
     7561 gcaaaaacta tgccatctta aatcaatata tatcgactct aaaaccctag tctttccaat
     7621 aatactaata aattttcaat ttttttatat ttatttttca cttactttaa gttgatttag
     7681 acttatttta attgtaaaat gagttatata taacttattt aaagttaaaa tagactgaaa
     7741 cttatatata aatatcaaat tttaagtata ttaatcaatt aaacctattt taatatatca
     7801 ttaaaaattt aggaggaaaa tataaaaatg aatttagatt tggaatttta tcaaaaaata
     7861 ttagaagctt cccatgatga aatatgtgtt tctgatgata aaggaataat aatatattgt
     7921 aataaagcat ttgaagaaaa ttatggtcta aaaaaagaag atattttagg aaaaaatgtt
     7981 tcttttttag aagactctgg atattcaaca aaaagcccca taccaattgt attaaaaaca
     8041 aagactaaat tttcactgga acaagatact caaacaggga aaaagcttat cataactgct
     8101 acccctatat ttgatgaaaa tggaaactta gaatttactg ttgaaaattg tagagatata
     8161 actgaactta ataatataaa aaataaactt gaagacacaa aaaagcaagt aaaaaaatat
     8221 aaatctgaag tagaaacact atacagaact gcacttagaa ttgaggatac tgtaattatg
     8281 gacggaatag ttatgagacc aatcataaac acagtaaatc atgtttctaa aacggatgta
     8341 agtgtacttt tattgggtga atctggaaca ggaaaaagct cacttgctag atatatacac
     8401 cacaacagca atagatctaa tggcccattt ataacaataa attgtgcaac tatatctcca
     8461 caacttcttg aatctgaact ttttggatat acttcaggtg cttttacagg tgcaagtact
     8521 aaaggtaaag ttgggctcgt agaattagct aatggaggaa ctcttttttt agatgaaata
     8581 ggagatatac cacaaaatct acaggcaaaa tttttgcaat taatacagga tagaactttt
     8641 actccagttg ggagcttaaa aaataaaaag gtcgatataa gaattatatc tgctacaaat
     8701 gttgatttag tttcaaaagt aaaagaaaaa aagtttagag aagatttata ctatagatta
     8761 aatgttatag aaataaaatt gcctcctctt agagaaagaa gggataatct agtggaaatt
     8821 ataaaatatt attttaatag gtactcaagt gacttcaatc taaataaaac tatttctaaa
     8881 gaagctatgg atgctattgc aaattataga ttcccaggca atataagaga attacaaaat
     8941 ataattcaaa aaatcttgct tacttgtaca gataatcata taacaataga tgacttacca
     9001 aacattctta caaaaaatat acatattacc aataatggaa ataaaacaca tatatcccaa
     9061 attaataagg ttattatatc tgactcaaaa tctactaatt ataaaaataa aaattttgac
     9121 actttaatta aagagtatga aaaaaatata attttggatg cttatgaaaa atttggtagt
     9181 tcttataaag tagccaaaca ccttgaaatc tcacagtcta aagccaatag gttaattaga
     9241 aagtatacta atacttaatt ttaaatttga taaataaaaa cttaacacta tttacatatt
     9301 gtaaatttgg ccatttactg ttattatgaa tatggttgaa attatttaaa taaatactgt
     9361 tgacttagtt tcatatattt accattaaac ttttatcata aatatcatat cataataata
     9421 tatttaataa gtctaataaa ctatacgagg tgtaaatatg ttaatgaata cccattttat
     9481 tatggcaaaa tcaatacttg ataatataga tgaaaataaa acattcttta taagcgaaaa
     9541 aaattttata tatggcaata taaagcctga tgctttttct aaatataaat taaaaaaaca
     9601 ttatttagat gagtcattta atatgattgt ttctaaaata aactatctat gcagtcttaa
     9661 tatagatagt ctttctaaat acttttcagt aagtagactt agtcaggaac taggagtcat
     9721 atgtcatttt ttatgtgatt ttttctgtgt agctcacagt gaacgttggg agtttaagca
     9781 tagcttaaat aaacatgtta cttatgaaag agaacttgga gcatttgcaa aagatgttga
     9841 tttatctaaa attaaatgtg gtactataaa tagtagtttt gagaagtttt ttactaaact
     9901 ttatagcgat tacaaaaaga aaactgatta tatgaatgat ttaaaatttt cagcttatac
     9961 ttgtaatagt gtcataaatt atatacttga ctctatttta tctaatacaa taaaatcata
    10021 tcatatagca aattgcggtt aacttaagaa tttttaaact tatataaact tataattgaa
    10081 tataattaaa atgactgctc tatagaatat aattttatac ttctctagga cagtcatttt
    10141 ttatactaac tatttatctc cattataaca tctatggcac tttttacact atctactaca
    10201 taatttgcac tttgctttac atcttccctt gccttagaca ttgcaaaact atatttaaat
    10261 ccttctaaca tgcaaatatc atttggagaa tccccaatag tagcaacttc atctggactt
    10321 acatttaacg tttttattac atgctctata cttcctcttt ttgacacact tttaggaact
    10381 atatttaaag tatatgttcc agaaaaatat atttctaaga cttcactaaa ctcacttttt
    10441 agataaagtt ctattctgga taactcttcc aaattttcag aacatacgcc tatatttcct
    10501 ataagattat caaaactact tcttttttca aagtctgggt caactataaa gtcactagaa
    10561 taatgtctaa aagcagtggt atcactaccc acaattacat cacccttata tttaaaataa
    10621 agttgtgcat cacttgactc aaatctatca atgacttttt ttactaaatt atcatctatc
    10681 gttcttttaa aaattacatt ataatcttta tcatatataa atgaaccatt ttcacataca
    10741 tagtatccat tcatatctaa actatctttg ataatattat gtgcttgttt aaaaattcta
    10801 cctgtagcaa cattaaactg tactcccttt ttttctattt cttcaattgc tactatatct
    10861 tcttttgtta tggttccatt ttcatataga gttccatcta aatcacaaaa tatatgtttt
    10921 atcataaatt aaaagcctcc aaaaacaatt ttatatttta ctaatacttt aatcaaaata
    10981 acttaaagct tttctaattg tattctcaac tcattaagca aatctctagt agctcttaat
    11041 cttatctttc ttctatcccc attaaatata tttttcttta ctattgtttt tccatttata
    11101 tatattgcag tataaaccag tcccacaggc ttctctttgg ttcctccacc aggtccagct
    11161 actccagttg tagatatacc tatattagct ttaagtcctt tagcaacgcc ctcagccatt
    11221 tctatagctg tttgctcact tactgctcca aactcttcca aagtttctct ttttactcct
    11281 aatcttttca ttttagaatc attagaatat gttacacaac cttcaagaaa tacagaggat
    11341 atacctggat agtttataag agatgaagaa accaaacctc cagtacaaga ttcagccact
    11401 gctattgtta gatttttttc tacaagtagc ttagaaacag catcttctaa agcagtctcc
    11461 ccttcagata tggaaatatc tccttcagta tatacatatt taccaactct actttttatt
    11521 ttttcttcta ctggttttat taatttaaaa gcttctcttt cattttcagc ctttgcagtt
    11581 attcttattg taacttctaa ttcttttgca tataaagcaa ctgttggatt agtctgctca
    11641 ttaattatat cgagaatttc taattctaga tttgactcac ctattccata taatcttaaa
    11701 gtcttagata ctagcatttc atttgtgaat tgttgtaagt aaggtttgac actctcatta
    11761 aacatagctt tcatttctct tggaggtcca ggcaatacta ttataaattt accatctttt
    11821 tttaaaattg cccctggagc tgtaccatta ttatttttta gtactatagc atcttttgga
    11881 aagtacactt gtttcatatt attttcggcc atttttttcc ctgttttaac aaagaaagat
    11941 tccaaaacct ctagtgaagg tttatgtagt tctaatttct gaccaaagta ttctgcagca
    12001 gtttcttttg tcatatcatc accagttggc ccaagaccac ctgtagtaat tacaaaatca
    12061 cttctcttta agctttcatc aaaacattct aaaagtcttt gtttgttatc tccaacagta
    12121 ctctgatggt atacttctat tcccaatgat gcaagttctt tagctaaaaa ttgagaattt
    12181 gtatttacta tatctcccaa taatatttct gttcctacac ttattatttc agctttcaaa
    12241 atttatcact ccttgattta tagccattaa gactagtctt aagttcataa caataatttt
    12301 agcaaaaata ataacataaa taaagttaaa aaatcattta aacatatctt taaactagat
    12361 tattattcta aaaccacaca taatataaac ttcgtatata gtggtacttt catcctcaac
    12421 tgttaattca tataattaag tatgtaaata aaaagtttac tttaaaataa taaaaattaa
    12481 aataggagtg tataatatga aaatagcagt tataatgggt ggaatatcat cagagagaga
    12541 agtttcttta aattcaggaa aagagatata taataacctt gataaaaata aatatgaagt
    12601 tgtaaaagta ataatagatg ataaaaaaga tatatttaca aagataccag aagatataga
    12661 ttttgcaata cttgctttac atggaaaatt tggtgaagat ggatgtatac aatcaatact
    12721 tgagactatg gatataccat actctggatg tggacctctt tgcagtggga tgtgtatgga
    12781 taaaaatata actaaaaaaa tgcttagaga ttcaaaccta cctactgctc catgggtttt
    12841 agtaaaatca gttgatgaaa tagactatga tgaaatagat aatataggtt atccagtatt
    12901 tataaaacca aactcaggag gttcaagtgt agccacattc tttattcatt ctaaggatga
    12961 agttgaagaa gcagttagaa aaggtctgga agttgatgaa tttgtaatga ttgaaaaata
    13021 tataccaggt ggagaatata cttcattcat attaaatgga gaagtgttcc ctacaatatc
    13081 tataaaatct gattcaggat tctttgatta tgaagctaag tactcagttg aaaaaggtgc
    13141 aaaggaagaa gttgtttact tagatgaaga acttcaaaaa agagtaaacg aaatttctga
    13201 gacttgttgg aaaattttta attgcaaagc atatgtaaga gttgatatga ttataagtga
    13261 aggtattcca tatgttcttg aactaaatac tcttcctgga atgactcaaa ctagtttaat
    13321 tcctagaagt gctgctgcta gaggtattaa gtacagtgaa ctattagata aacttataga
    13381 atactcttta aattagatga aataatttga ggtggtaatt tgatattttc aaatctaaaa
    13441 ctaaatgata atgaaccaat ttatatacaa cttaaaaatt atataagtga tatgatatca
    13501 aaaggactaa ttccagacaa tagtaagctc ccttctacaa gggagcttag tcagctttta
    13561 caagttagcc gaaattctgt agttttaact tatgaagaat taaaatcaga aggattaatc
    13621 tactctattt caggaaaagg tacatttgtt aaatcaaaga ataagtcttc aaatactaca
    13681 tggtcattaa actgggattg tttagagaat acatactcta aaaaagccaa tgaattggac
    13741 attataaaaa gtgaaattcc ttggagctct gacctgattt cctttaaaag tatttctcca
    13801 gatggagatt tattcgacat agaagaatta aaaaaatcct ttttaaatag aatttcacta
    13861 gaaggacata aattactcaa ctatggatat gcacaaggtt ataagcccct tattgactat
    13921 ttactagaat atatgacaaa taagggtgct gatataagta ataaagatat actaataaca
    13981 aatggattca cagaaggctt tgatattatt atgtcatctt ttacccaaga aaaagactac
    14041 ataatatgtg aaaatcctac tcataatact gctataaaaa ttatgaaatc tcataacctc
    14101 aatatcttag gtgtagatat aaatgaagat ggtttggact tcaatatgct agaagacaat
    14161 ttagttaagt ataaaaataa aataaagttt gcatacatta caccctctta tcacaatcct
    14221 acaggaattg taatgactcc tgaaaatagg tacaaattct ataatcttat gaaaaaatac
    14281 aatatagcaa ttatagaaga tggatttaat gaagaattac tctacaatag ttctcatata
    14341 tttcctatct gttccctaga taatatgaat aatggggtcg tatatattgg tagtttttca
    14401 aaaattttat ttcctggaat gagaattgga tggatatttg cagataaaaa agtaatcaat
    14461 aagctagaaa gtgtaaaaag gtgcagaaac atacatgtat cctttttgga ccaaggaatt
    14521 ttatttgatt atttaagtaa tggaggtttt gaaaaataca ttaaaaaaat acgtaaattc
    14581 tatggggaca aatttaactt tgcatataag tgtataaaaa aatatataaa aacagaatat
    14641 atcttgggtg atggtggttt gcatatattt ataaaactaa aaaatataga tactagagtt
    14701 ttattagaaa aatgttatga aaaaaatgtt atatttatgc ctggagattt attttttaca
    14761 gataactctg gttttgatac tttaagactc ggattttcta ggttgtcttt tgaagacatt
    14821 gaaattggaa taaaaataat tggagaaact ataaatgaaa tgttctaggt taactaaata
    14881 ttgttagcct agtttatt
//
LOCUS       DAEPHU010000092        14897 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 01A10CD0081
            SAMN05941466-rid12468953.denovo.092, whole genome shotgun sequence.
ACCESSION   DAEPHU010000092 DAEPHU010000000
VERSION     DAEPHU010000092.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941466
            Sequence Read Archive: SRR6291087
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 14897)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14897)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068158.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 22:43:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,892
            CDSs (total)                      :: 3,805
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 87
            rRNAs                             :: 8, 1, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 55
            CDSs (without protein)            :: 55
            Pseudo Genes (ambiguous residues) :: 0 of 55
            Pseudo Genes (frameshifted)       :: 21 of 55
            Pseudo Genes (incomplete)         :: 28 of 55
            Pseudo Genes (internal stop)      :: 16 of 55
            Pseudo Genes (multiple problems)  :: 8 of 55
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14897
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941466-rid12468953.denovo.092"
                     /strain="01A10CD0081"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            265..1026
                     /locus_tag="KR231_003235"
     CDS             265..1026
                     /locus_tag="KR231_003235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896901.1"
                     /note="N-terminal region resembles flavodoxins. C-terminal
                     ferrodoxin region binds two 4Fe-4S clusters; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EFR1 family ferrodoxin"
                     /protein_id="HBH0005575.1"
                     /translation="MIGIYFSGTGNSRYCVEKFLQEYDITANSYSIEDNELLQHINNH
                     ENIIFSYPVQYSNVPKILKDFIINHSTLWNGKRVFIIATMALFSGDGSGVLSRILKKY
                     GAITVGGLHVKMPDSIGDEKVLKHSLEYNRKLVIKAEKKVTKAAKKLKHGSPPKEGLG
                     FLSHIVGLFGQRLYFINKTNMYTDKLKINTEECIVCGKCVNLCPMKNLVIKNCMIVAN
                     GQCTMCYRCVNNCAKKAITLLGKKVVEQSNIKKYM"
     gene            1091..1873
                     /locus_tag="KR231_003236"
     CDS             1091..1873
                     /locus_tag="KR231_003236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PhzF family phenazine biosynthesis protein"
                     /protein_id="HBH0005576.1"
                     /translation="MEYYIVDSFATKLFKGNPAGVCVLDRRIPLELMQKIAEENNLPE
                     TAFVVKGKGNYELRWFTPKAEIDLCGHATLAAAYVISNFIDVNVKRIDFFTQSGKLEV
                     TRNGNLYEMIFPEIMPIEIELSPQQANLIGCVPSAVYSSRDLILLLNSEQEVINYKPN
                     YAQLRKLTDWLGIIITAQGSNTDFVSRYFCPELDSEDPVTGSSHCNLIPYWSEKLGKH
                     KMVAAQLSNRGGIIQCEVLKDNTVKISGEAVLFMQGTIKIDI"
     gene            2140..2559
                     /locus_tag="KR231_003237"
     CDS             2140..2559
                     /locus_tag="KR231_003237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjdF family protein"
                     /protein_id="HBH0005577.1"
                     /translation="MDKISGKLTVLFEEPFWVGIFERQDGKKYEACRVVFGAEPKEVE
                     VYEFILERFFSLDFGSIKLEKNVTKDNIGYKRMQRKVKKEQEKETIGTKAQNALKLQY
                     EERKQDRKNLAKNRKEEEKERLFNLKQEKRKAKHKGH"
     gene            complement(2662..2928)
                     /locus_tag="KR231_003238"
     CDS             complement(2662..2928)
                     /locus_tag="KR231_003238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1294 domain-containing protein"
                     /protein_id="HBH0005578.1"
                     /translation="MKNFILIYFIVINSIAFFSMYIDKKRAIRNEWRIKEATLMSIAV
                     IGGSIGSIIGMYSFRHKTKHIKFTFGIPFILFLQFLLVYFYILK"
     gene            3155..3856
                     /locus_tag="KR231_003239"
     CDS             3155..3856
                     /locus_tag="KR231_003239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454365.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0005579.1"
                     /translation="MKFIVEKEVFDKLENVCFGVVVAKGIDNTKEIERISNLLDISID
                     RVEDYFKDKKVKESEEIIPYREAFRSLGMNPNKFMSSIEAMTTRVAKNKKLPHINPIV
                     DLGNSISLKYLLPMGAHDMDFRNDDVYVRFSKKGDKFVPFGETDVELMEEGELIYSVG
                     DMVKTRRWIWRQGEEGKITNSSKNIFFPIDGFTDANLDKVMSAREELAKLLKEIFNCE
                     IKVGFVDKDNPEMEI"
     gene            3938..4546
                     /locus_tag="KR231_003240"
     CDS             3938..4546
                     /locus_tag="KR231_003240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HBH0005580.1"
                     /translation="MKKTIIKNVNPMIENKFIGLFEIEYKNKLDEDKVWMVASRKSSE
                     QLKNIYLKNEEDSVDAVVIVGLHKSSKKLILIRQFRVPINGYIYELPAGLVDEGESID
                     ISVERELREETGLTLLEIKKNKSIDKVYLSPGMSDESVAFVYCICDGDITDEFLEPDE
                     EIEALLISQEDAKEILQSNHKIDTKAFLILQMFVSLGAKLFE"
     gene            4870..5334
                     /locus_tag="KR231_003241"
     CDS             4870..5334
                     /locus_tag="KR231_003241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4624 domain-containing lipoprotein"
                     /protein_id="HBH0005581.1"
                     /translation="MKKLVIILISIISMVSLTACKKSNESKYNNLNNKESGQTTIEMD
                     LDKNYDTSDPFVNARLFCVSNDIDVLDTEISFKMDGDSGIVEIKDNKTDETLWSNTWH
                     GSVDNDTFTISLSNIQKEKEYAICFTGIKINHAVVKVTFESNLVKEKEKPSK"
     gene            5971..6987
                     /gene="gap"
                     /locus_tag="KR231_003242"
     CDS             5971..6987
                     /gene="gap"
                     /locus_tag="KR231_003242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011948756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glyceraldehyde-3-phosphate dehydrogenase"
                     /protein_id="HBH0005582.1"
                     /translation="MKIKVGMNGFGRIGRAVLRIAQEELGDNIEIVAINARATTESLA
                     HLFTYDSCYGTFRGEVEAKDEDTLVVNSKEIKILRYNDPEELPWKELGVDIVIESTGL
                     FTQREKAEKHIKAGAKKVIITAPGKNEDITIVIGVNEKEYDNEKHNIISNASCTTNCL
                     APFAKVLDEKFGIVKGLMTTVHSYTNDQRILDKSHKDLRRARAAAESIIPTTTGAAKA
                     VSRVLPQLEGKLNGFSLRVPTPTVSLVDLVCELKENVTSEQVNSVLKDAAEGELKGVL
                     GYCDKPLVSIDYKGDSRSSIIDALSTMVIEDNMVKVVSWYDNEWGYSSRTVDLVKYVA
                     EKLK"
     gene            7382..8551
                     /locus_tag="KR231_003243"
     CDS             7382..8551
                     /locus_tag="KR231_003243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0005583.1"
                     /translation="MEKLTDRRQVKAVSMETFIFLILLVVGFGYVGSIMGAGMMFKVI
                     MSTAHALLLETVFLIMAMAVLAGALSALLSEFGVIALINKIFAVFMKPLYGLPGASIA
                     GAITTYLSDNPAIIPFAKDKTFTQYFKQYQVPALCNLGTAFGMGLILTTFMISQGTEY
                     VLPALIGNLGAIIGSVISVRIMLTFTKKFYKYNPEEDKATGTLEKKDEFREIREGNVF
                     QRALDAILEGGKMGVDMGMAIIPGVLVVCTLVMLLTFGPSTDPVTGQEVYTGAAYEGI
                     KLLPVIGDKLGFILEPLFGFTSPEAIAFPITSLGAVGAAMSLVPEFIKSGAITPNDIA
                     VFTAMGMCWSGYLSTHIGMMDALNARQLAGKAILSHTIGGLCAGAAAHFIFTLVG"
     gene            8931..13184
                     /locus_tag="KR231_003244"
     CDS             8931..13184
                     /locus_tag="KR231_003244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-hydroxyacyl-CoA dehydratase"
                     /protein_id="HBH0005584.1"
                     /translation="MDELFHIGIDVGSTTVKVVVLNNSNNIVHKEYRRHYSDVKKSVK
                     EVLNGIYEKLGDINTTIIITGSGGIGISKKLGVKFVQEVISSTKSIEYFHPETDVVIE
                     LGGEDAKITYLSGGIDQRMNGICAGGTGAFIDQMASLLKTDASGLNELAKGYNVIYPI
                     ASRCGVFAKTDIQPLINDGANQTDIAMSIFNAVVVQTVSVLSCGRKIEGNVAFLGGPL
                     YFLSELREAFKRVLDLKDENIIFPENAQLYIAIGAGLLSVDEDNIQLKSLIEKLDSIK
                     NIEDGEVNLLEPLFKDKNEYEEFSRRHEKEKINYVDINSIKSNCYLGIDAGSTTTKAA
                     LIDEDGRLVYSYYNSNEGNPLKTTIKVINEVYDILPKNIKILSSTVTGYGEGLIKKAL
                     KIDNGEIETIAHYKAAKFFNKDVDFILDIGGQDMKCLKIKDGVIDNIILNEACSSGCG
                     SFLETFASSLSMTIEEFAHEGIYSQNPVDLGSRCTVFMNSRVKQAQKEGASVGDISAG
                     LSYSVIKNALFKVIKIRDLNEIGNNIVVQGGTFYNDLVLRSFEKLIGKNVIRPNISGI
                     MGAFGSALIAKEKYESGYKTSLLSKEELNNIKLEASVTRCKGCSNHCLLTINKFSDNE
                     IFISGNRCEKGEAIYGDKKIGLEKKKPINLFKYKYNRIFRYKPLEKEEAKNGEIGIPR
                     VLNMYEDYPFWFTFFNAMGFRVVLSDRSSKQLYETGITSIASETVCYPGKLVHGHIEN
                     LIAKGIKNIFYPSVTNENKEDSNADNYYNCPVVISYSEVIKNNVENIRNKNINYINPF
                     ISLNDKEKLKKRLYDELSRHFSDIKITKEEVNHAVDKATDEQNLFKMEIQAAGERALK
                     EIKERNMKGIVLCGRPYHIDPEINHGMPELINSLDMAVLTEDSICHLANVQRPLRVVD
                     QWVYHSRLYKAASFVRDKNYLELVQLNSFGCGLDAVTTDQVQEILNEKSKIYTIIKID
                     EGNNLGAAKIRMRSLKAAMFERESKNIDVKNIKVNRIQYAKNNQITNKHTILAPQMSP
                     IHFQFLEKAVNLSGYNIEILKDTDSSVIEEGLRYVNNDACYPAIIVVGQLITALKSGK
                     YDLNNTSVTITQTGGGCRATNYIGFLRKAIYDAGFKDIPVIALSVNGIEDSGIMDNIS
                     LKLINRLFMSVVYGDLLMKVLYRVRPYEKVTGSANALYEKWVDICKSSLVKAKISVFT
                     RNIKDIVKEFDNLEILDIKKPKVGLVGEILVKFHPIANNNLVDILEREGAEAVVPDLT
                     NFFLSCAFNTIYKHTHLEGSRKSRMIGEAFIYITGIYQRVYKKALDKSERFYAPANIK
                     NVAKSTEPVVSLGNQTGEGWLLTGEMVELLNEGVENIICMQPFGCLPNHIIGKGSIKE
                     LKRLYKNANIIPIDYDPSASEVNQLNRIKLMLSKAFKNI"
     gene            13333..13827
                     /locus_tag="KR231_003245"
     CDS             13333..13827
                     /locus_tag="KR231_003245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylated-DNA--[protein]-cysteine
                     S-methyltransferase"
                     /protein_id="HBH0005585.1"
                     /translation="MSLVYDVYKSKLGNLYILSEDGFIVSIYIGDEKFNNLKNECIKK
                     GIDIKRSKEDLKEAISQIDDYFNGKRKVFNLNIRIEGTEFQKSVYREMLKIPYGETLC
                     YSDIARNINNPKSVRAIGQASKSNKIPIIIPCHRVVGKKDIGGYMGNHSDLKEILLNL
                     ERQS"
     gene            13943..14320
                     /locus_tag="KR231_003246"
     CDS             13943..14320
                     /locus_tag="KR231_003246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="monooxygenase"
                     /protein_id="HBH0005586.1"
                     /translation="MCDKVIASKYHEKGFNCAESVIKAYNEEFNTDIPVCLGSGLGSG
                     CGVASLCGAVNASNIIIGYVKGRNHEDESTKAKVYAKDLTTTVRKEYGSELCIDLKKD
                     LVACREIMDFAYDSLKETLKKEL"
     gene            14526..>14897
                     /locus_tag="KR231_003247"
     CDS             14526..>14897
                     /locus_tag="KR231_003247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SufBD protein"
                     /protein_id="HBH0005587.1"
                     /translation="MKNLNLLINKLYSKNHNEAYKTFLFLENESLKSNITYCFFDSFL
                     EMIDNENSYIRTRGLLLISANAQWDIDNKIEINIDSILSHIVDKKPSVSRMFIKSIPN
                     ITKYKENLINRIKMELSNADIS"
BASE COUNT         6064 a         1480 c         2624 g         4729 t
ORIGIN      
        1 atatatgctt aaggaagtat agcttactaa tattattaaa atgtatattt aaaatgataa
       61 aaaaagaatt agacaagtat ttagtaaatt gactatgcaa aattctatca agcaggaacc
      121 ctatgacttt agtcatggga ggttcagtag gtaacttgtt gaattaagtt tatattattt
      181 aaataaacta cttaatttag ataatataaa aagtcagaat tttaagaata gagctatata
      241 atcttagcta ttaggagaat tactatgata ggaatatatt ttagtggaac aggaaattca
      301 agatactgtg tagaaaaatt tttacaagaa tatgatataa cagcaaattc ttattctatt
      361 gaagataatg aacttttaca gcacatcaat aatcatgaga atattatttt tagttatccg
      421 gtgcaatata gtaatgtgcc aaaaatattg aaagatttta taataaatca ttcaactttg
      481 tggaatggta aacgtgtttt tattattgca actatggctc tatttagtgg agatggctct
      541 ggtgtgttat ctagaatatt aaaaaaatac ggtgctataa ctgttggtgg attacatgtg
      601 aagatgccag atagtatagg agatgaaaag gtattaaaac attctttaga gtataataga
      661 aagcttgtaa taaaagcaga aaagaaagta actaaagctg ctaaaaaact gaaacatggg
      721 tcaccaccaa aagaagggtt aggttttttg agtcatattg tagggttatt tggacaacga
      781 ttgtatttta tcaacaaaac aaatatgtat acagataaac taaaaattaa tactgaggaa
      841 tgtattgtat gtggtaaatg tgttaattta tgtccaatga agaatctagt aattaaaaat
      901 tgtatgattg ttgcaaatgg gcaatgtaca atgtgttatc gttgtgtaaa taattgtgct
      961 aaaaaagcaa ttacattgtt aggtaaaaaa gttgttgaac agagtaatat taaaaaatat
     1021 atgtaagaaa tttaaagttt tattgaatgt aaattgatgt atattttatg ttagaaagag
     1081 aggttaaata atggaatact acatagttga ttcatttgca actaaactat ttaaaggaaa
     1141 tcctgctgga gtttgtgttc ttgacagaag aataccttta gagttaatgc agaaaatagc
     1201 agaagaaaac aatttaccag aaacagcatt tgtagttaaa ggtaaaggaa attatgaatt
     1261 acgatggttt actcctaaag cagaaattga tttatgtggt catgcaactt tagcagcagc
     1321 ttatgtaata tcaaatttta ttgatgttaa tgtaaaaagg atagatttct ttactcaaag
     1381 tggaaagctt gaagttacac gaaatggaaa tctatatgaa atgatatttc cagaaataat
     1441 gcctattgaa atagagttat caccacaaca agctaatttg ataggctgtg taccaagtgc
     1501 tgtttattct tcaagagatt taatcttatt gctaaacagt gaacaagaag ttataaatta
     1561 taaacctaat tacgcacaat tgcgtaaatt gacagactgg ttaggtataa taatcacagc
     1621 acaaggaagt aatacagatt ttgtatcaag atatttttgt ccagaattag attcagaaga
     1681 ccctgttact ggttcatcac attgtaatct tattccatac tggtctgaaa agttgggaaa
     1741 acacaaaatg gtagctgctc aactttctaa tcgtggtggt ataattcagt gtgaagtgtt
     1801 gaaggataat actgtgaaaa tttctggtga agcagtcttg tttatgcagg gaacaataaa
     1861 gattgatatt taaataagta taataactaa tttattatga aaaataatta attttcttag
     1921 tgttaacaat aataaagtag agttaaaaaa cttgatttca cttaaatcaa tatgatagat
     1981 gttgatacta agattgacaa gcatgattaa aaaagataat atttaatcta taaagataaa
     2041 aacacagtct ggttggtagt ccagacgcag caatagctgt cagtaacctg cctccttggt
     2101 tgtccgttct ttagaaagta atttaaggag gaactagcaa tggacaaaat tagtggaaaa
     2161 ttaacagtct tatttgaaga accattttgg gtaggtatat ttgaaagaca agatggtaaa
     2221 aaatatgaag catgtagggt agtttttgga gcagaaccta aagaagtaga agtgtatgaa
     2281 tttatacttg aaagattttt ctcattagat tttggtagca ttaaattaga aaaaaatgtg
     2341 accaaagaca acattggata caaaagaatg cagagaaaag taaaaaagga acaagaaaaa
     2401 gaaactatag ggactaaggc tcaaaatgct cttaagcttc aatatgaaga aagaaaacag
     2461 gatagaaaaa acctagctaa aaatagaaaa gaagaagaaa aagaaagact atttaatttg
     2521 aaacaagaaa agagaaaagc taaacataag ggtcattaat tttaattaaa tatcttttta
     2581 ataattgcta gaaaaaggtg tataaaattt ttaattttat acaccttaat ttattgaaaa
     2641 gaataaggtt ttatatttca attactttaa aatataaaaa tatactaata aaaattgtaa
     2701 aaatagtata aatggtatac caaatgtaaa tttaatgtgt ttagttttat gtctaaaaga
     2761 atacattcca attatagaac ctatactacc tccaattact gctatagaca taagagtagc
     2821 ttcttttatt ctccattcgt ttctaattgc tcttttctta tctatgtaca ttgaaaagaa
     2881 agcaatagaa ttaatcacta taaaatatat tagaataaaa tttttcacag tcttgcctcc
     2941 ataaaaatat attatacatt ataaaacaag atatttgttt tggaaagtta aatttgtaat
     3001 tagtacatat aaaatatttg ataagaacaa atataatatt aattggaaaa tttaaaaaaa
     3061 ttaaacaatt agcaaatagg gggtatattt ataagacaca aagtgataaa atctatttag
     3121 aaaataatgt aaaataacag gaggataaag caaaatgaaa tttatagtag aaaaagaagt
     3181 ttttgataaa ttagaaaatg tatgctttgg tgtagtagtt gcaaaaggaa tagataatac
     3241 taaagaaata gaaagaataa gcaacctttt agatataagt atagatagag tagaagatta
     3301 cttcaaagat aaaaaagtaa aggaatcaga agaaattata ccatatagag aggcatttag
     3361 aagtctaggc atgaacccaa ataaatttat gagttcgata gaagcaatga caacaagggt
     3421 tgctaagaat aagaaacttc ctcatataaa tcctattgta gatttaggaa actctatttc
     3481 tttaaaatat ttacttccaa tgggtgctca tgatatggat tttagaaatg atgatgtata
     3541 tgttagattt tctaaaaaag gggataaatt tgtaccattt ggagaaactg atgttgaatt
     3601 aatggaagaa ggagaattaa tttattcagt tggagacatg gtaaaaacta gaagatggat
     3661 atggagacaa ggagaagaag gaaaaattac taatagctca aaaaatatat tttttcctat
     3721 agatggtttt actgatgcta atttagataa ggtaatgagt gcaagagaag aattagcaaa
     3781 attgttaaag gaaatattta attgtgaaat taaagtaggt tttgtagata aagataatcc
     3841 tgaaatggaa atataataag ttgttgaata cttgttaaga tattatattt acttaatgat
     3901 gttaaaaagg tattaaaaaa gaaaggtcgt agtaaatttg aaaaaaacta taataaagaa
     3961 tgtaaatcca atgattgaaa ataagtttat aggacttttt gaaatagagt ataaaaacaa
     4021 attagatgaa gataaggttt ggatggtagc atcaagaaaa agtagtgagc aattaaaaaa
     4081 tatttatttg aagaatgaag aagatagtgt agatgcagtt gtaatagttg ggcttcataa
     4141 aagtagtaaa aaattaattt taataagaca atttagagta cctattaatg gatatatata
     4201 cgagttacca gcaggtcttg ttgatgaagg agagtctata gatatttccg ttgaaagaga
     4261 acttagagaa gaaacaggac ttactctttt agaaattaaa aaaaataaaa gtattgataa
     4321 agtttattta tctcctggaa tgagtgatga atctgttgcc tttgtttatt gtatatgtga
     4381 tggtgatata acagatgaat ttttagaacc agatgaagag attgaagcgc ttttaatttc
     4441 gcaagaagat gcaaaagaga ttttacaaag taatcataag atagacacaa aagcattttt
     4501 gattttacaa atgtttgtga gtttaggagc taaattattt gaatagatat atagaaaaga
     4561 ggttatatag aagagtaaaa taataaagtt tattttactt gtgtaaatta taatctcttt
     4621 ttttatacaa taaagtataa ttttgtgtat ttttaaataa gtgatttgac tcttaaattt
     4681 tcataatatg ttataaacca atttaagata ctacaataat taaaattcca aaattattta
     4741 acatatttgc aattaaaatg agaaaatgta aaggctgaat gattgaaaaa tttgatgtaa
     4801 aatagtagct tagtttaata ctatagtttg tagggttaaa aattagaaat tgtaagggag
     4861 ataaattcta tgaaaaaatt agttattatt ttaattagta tcattagtat ggttagcttg
     4921 acagcttgta aaaaaagcaa tgaaagtaaa tataataatt taaacaacaa agaatccgga
     4981 caaacaacca ttgaaatgga cttagataaa aattatgata cttcagaccc atttgttaat
     5041 gcacgtttgt tttgtgtgtc taatgatata gatgttttag acacagagat ttcttttaaa
     5101 atggatggag atagtggtat tgtggaaata aaggacaata aaacagatga aactttatgg
     5161 agtaatacat ggcatggaag cgttgataat gatacattca caatttctct ttctaatata
     5221 caaaaagaga aagagtatgc tatatgcttt actggaatta aaataaatca tgcagttgta
     5281 aaggttactt ttgaaagcaa tttagttaag gagaaagaaa aaccctcaaa ataaattcca
     5341 gcttttctat aacttgatat tcagtacata aaagcagttg atatttatga ttgactgctt
     5401 tttcttatca aaaaggatag gttgtgcatt tttacttgaa atagtttatg cacatcaaaa
     5461 gttggtgagc atgatattgg aaatggtaag catgaaatct tgataataca aggaaataaa
     5521 tttaagtttt caattaagta tatttccata atttagttaa caataagcta attattattt
     5581 atattttgat atataaataa taattgtagc aaattttaaa aaatcatata ttttttgaac
     5641 taaataaaaa tttattttta ttattttaaa ttagaggaga ttcttgaaga tatattattt
     5701 ttaaaaataa gtatagttta aaaattcaaa aaaaagatgg caaaatatgt cccaagggac
     5761 attgagtaaa ataaatgatt tcagcttatt tacactaaaa agtacatact aaatgagggg
     5821 taaaataaag aaaaatgata tactaattgt cttttgataa taaaaaaaca tggaatttga
     5881 ttatttaatc aagaaaaagt attgaacaaa tgatttattt agtgtacaat aatcatgtaa
     5941 aaacatagta atggagggag acatttcata atgaaaatta aggtaggaat gaacggattt
     6001 ggaagaatag gaagagctgt attaagaata gctcaagaag aattaggaga taatatagaa
     6061 attgtagcca taaatgcaag agcaacaaca gaatctttgg cacatttatt tacatatgat
     6121 tcatgctatg gaacttttag aggtgaagta gaggcaaagg atgaagacac tctagtagta
     6181 aactctaaag agataaaaat attaagatat aatgacccag aagaattacc ttggaaagaa
     6241 ttgggggttg atatagtaat agaatcaaca ggattattta cacaaagaga aaaggcagaa
     6301 aaacatatta aagcaggagc aaaaaaagta attataacag ctccaggaaa aaatgaagat
     6361 ataactatag ttatcggagt taatgagaaa gaatatgata atgaaaagca caatataatt
     6421 tcaaatgcat cttgtactac aaattgtcta gctccttttg ctaaagtatt ggacgaaaaa
     6481 tttggtatag taaaagggtt aatgactaca gtacattcat atactaacga tcaaagaata
     6541 ttagataaaa gccataaaga tttgagaaga gcaagagcag cggctgaatc tataatacct
     6601 accactacag gagcagcaaa agctgtgtca agagtactac cacaattaga aggaaaatta
     6661 aatggttttt cacttagagt accaacacca acagtttcac ttgttgattt agtgtgcgaa
     6721 cttaaagaaa acgttacatc tgagcaagtt aactctgtgt taaaagatgc tgctgaagga
     6781 gaattaaaag gtgttttagg atattgtgac aagccacttg tttctataga ttataaagga
     6841 gattcaagat catctattat agacgctcta tccacaatgg ttatagaaga caatatggtt
     6901 aaggtagttt cttggtatga taatgaatgg ggatattctt caagaactgt tgacttagta
     6961 aaatatgtag ctgaaaaatt aaaataatat atatttctta aagcaaattt taaaaaaatt
     7021 ttttaaaaaa attatataaa actaaaaaaa aagattatga aaaatattga aggaaaaatt
     7081 ttttcataat cttttttctt tcatgcaaaa agatacaagt tacaacttat atttgcatat
     7141 taggtcgtta gagaagtata tatatattta gtaaggaatc atacttttta taaaatgaaa
     7201 gataagatgt cgaaaacttg cataaatctg aaaaattttt attattaaaa tactgatttc
     7261 cattttaaaa atgataaaaa aatgacaaat aaagttgcaa atagtaatac ttataagtat
     7321 aattaaaaaa gagaaaaggt tttgttaaac tttataacaa aaaaagaagg gatgattcaa
     7381 aatggagaag ttaacagaca ggagacaggt taaggcagta agcatggaaa ccttcatttt
     7441 cctaatatta ctagtagttg gttttgggta tgttggtagt attatgggag caggaatgat
     7501 gttcaaagta ataatgagta cagcacatgc tttactattg gagacagttt tcttaattat
     7561 ggctatggca gttcttgcag gcgcattaag cgcactactt tcagagtttg gagtaatagc
     7621 gttaattaat aaaattttcg ctgtatttat gaagccttta tatggactac ctggtgctag
     7681 tatagcagga gctataacaa cttatttatc agataatcca gctattatac cttttgctaa
     7741 agataaaaca ttcacacagt attttaaaca ataccaagtt ccagcattat gtaacttagg
     7801 aacagccttt ggtatgggac ttatcttaac aacatttatg atttctcaag gtacagaata
     7861 tgtacttcca gcattaattg gtaatttagg tgcaattata ggtagtgtca taagtgttag
     7921 aataatgttg acatttacta agaagtttta taaatacaat ccggaagaag ataaagcaac
     7981 aggaacatta gagaaaaagg atgaatttag agaaatcaga gaaggaaatg tatttcaaag
     8041 agctttagat gcaattcttg aaggtggtaa aatgggggta gatatgggaa tggctataat
     8101 tcctggagtc ctagtagtat gtacattggt gatgttatta acttttggac catctacaga
     8161 tcctgttaca ggtcaagaag tttatacagg agctgcatat gaaggaataa aattacttcc
     8221 agttattgga gataaacttg gatttatatt agaaccatta tttggattta catcaccaga
     8281 ggcaatagca ttccctataa cttcattggg agctgttggc gcagcaatgt ctctagttcc
     8341 agagtttata aagtcaggag ctataactcc taatgatata gcagtattta cagctatggg
     8401 tatgtgttgg agtggatatt taagtacaca tattggtatg atggatgcat taaatgctag
     8461 acagttggca ggtaaagcta ttctttctca tacaataggt ggtttatgtg caggagcagc
     8521 tgctcacttt atatttacac tcgtaggata aatgtaatca gctaagataa aaaataatat
     8581 acaaaaaatg gttgttgata tgtaataaga atttacatat caacaaccat ttttttctga
     8641 ctaaagataa tttataatac ataaacatta agtggatatt agagttaagt tatatttatg
     8701 taaaaagtaa caaaaatctg tagaaattta tgacaaaatt tagtacacta actatatgtt
     8761 cttatttaaa atttaaggtt agaattagga attacctagt agagtaagct ttgattaata
     8821 aaagaatcat aaaataaaaa tattagtcat aaagattata aataacttac ttaaaataaa
     8881 gccatagaac ttacaaaaat taaaaaagca tataaatatg gaggggtaca atggatgaat
     8941 tatttcatat aggaattgat gtaggttcta caacggtgaa ggttgtggta cttaataata
     9001 gtaataatat agttcataaa gaatatagaa gacattattc tgatgtaaaa aaatcagtta
     9061 aagaagtact aaatggtata tatgaaaaat tgggagatat aaatactacc attataataa
     9121 ctggttcagg tggaattgga atatcaaaaa aattaggtgt aaaatttgtt caggaagtta
     9181 tatctagtac aaaatcaata gagtattttc atcctgaaac tgatgttgtc atagaacttg
     9241 ggggtgaaga tgcaaagata acatatctaa gtggaggaat agaccaaaga atgaatggaa
     9301 tatgtgcagg tggcactgga gcattcatag accagatggc atcactttta aagacagatg
     9361 ccagtggatt aaatgaactt gctaaagggt ataatgttat atatcccata gcttcaagat
     9421 gtggtgtttt tgctaaaaca gatattcaac ctcttataaa tgatggagcc aatcagactg
     9481 atatagcaat gagtattttc aatgcagttg tcgtacaaac tgtgagtgtc ctttcttgtg
     9541 gaagaaaaat agaaggaaat gttgcgtttt tgggtggtcc attgtacttt ttatctgaac
     9601 ttagagaagc atttaaaaga gtattagatt taaaagatga aaacataatc ttcccagaaa
     9661 atgcacaact ttatattgct attggagcag gattattatc agtagatgaa gataatatac
     9721 aactaaaatc tctaatagaa aaattggata gtataaagaa tattgaagat ggagaagtaa
     9781 atttattaga acctttattt aaagataaaa atgagtatga agaattttca agaagacatg
     9841 aaaaagaaaa aataaattat gtggacataa attcaataaa aagcaattgt tatttaggaa
     9901 ttgatgcagg ctcaactaca actaaagcag cacttattga tgaggatgga agacttgtat
     9961 attcttatta taatagcaat gaaggaaatc cattaaaaac aaccattaaa gttataaatg
    10021 aagtatatga tatattacca aaaaatatta aaatattgag ttcaactgta actggatatg
    10081 gagaaggtct tattaaaaaa gctcttaaaa tcgataatgg agagatagag actatagcac
    10141 attacaaagc tgctaaattt ttcaacaaag atgtagattt tatacttgat attggtggtc
    10201 aagatatgaa gtgcctaaaa ataaaagatg gagtaattga taatataata ttaaatgagg
    10261 cttgttcatc aggttgtggc tcatttttag agacatttgc aagttcttta tctatgacaa
    10321 tagaagaatt tgcgcatgaa ggtatttatt ctcaaaatcc tgtagattta ggttcaagat
    10381 gtactgtatt tatgaattct agagtaaaac aagctcaaaa agaaggtgca agtgttggag
    10441 atatatcagc agggctatct tattcagtaa taaaaaatgc tttatttaaa gtaataaaga
    10501 ttagagattt aaatgagatt ggtaataata ttgttgtaca aggtggaacc ttttataatg
    10561 atttggtgct tagaagcttt gaaaaactaa ttggaaaaaa tgtaattaga cctaatattt
    10621 caggaattat gggagctttt ggttcagcac ttatagctaa agaaaaatat gaaagtggat
    10681 acaaaacatc cttgttatct aaggaagagt tgaataatat caagctagaa gcaagtgtaa
    10741 ctagatgtaa aggttgttca aatcattgtc ttcttacaat aaataaattt tctgataatg
    10801 aaatttttat ttcaggtaat agatgtgaga aaggtgaagc tatttatggt gataaaaaaa
    10861 taggattaga aaagaaaaaa ccaataaatt tatttaagta caaatacaat agaattttta
    10921 gatacaaacc attggaaaaa gaagaagcaa aaaatgggga aatagggata ccaagagtat
    10981 taaatatgta tgaagattat ccattttggt ttactttttt caatgctatg ggctttagag
    11041 ttgtactttc agataggtca tcaaaacagt tatatgaaac tggtataact agtattgcat
    11101 ctgaaacagt ttgttatcca ggaaaattag ttcatggaca tatagaaaat ttaattgcaa
    11161 aaggtataaa aaatatattt tatccaagtg taacaaatga aaataaagag gattcaaatg
    11221 cagataatta ttataattgt cctgttgtaa tatcatattc tgaagtaata aaaaacaatg
    11281 tagagaatat aagaaataag aacataaatt atataaatcc atttataagt ctaaatgaca
    11341 aggaaaaatt gaagaaaaga ctctatgatg aattatcaag acatttttct gatataaaaa
    11401 taactaaaga agaagttaat catgcagttg ataaagctac tgatgaacag aatttattta
    11461 aaatggagat acaagcagca ggtgaaagag cacttaaaga aataaaagaa agaaatatga
    11521 aggggattgt gttatgtgga agaccatatc atatagaccc agaaataaat catggaatgc
    11581 cagagcttat aaattcatta gatatggcag tgcttactga agactctata tgtcatttag
    11641 ccaatgtaca aagaccactt agagttgtag accaatgggt atatcattca agattgtata
    11701 aagcagctag ttttgtaaga gataaaaact atttggaact tgttcaactt aattcatttg
    11761 gctgtggatt agatgcagta actacagacc aggttcaaga aatacttaat gaaaaatcga
    11821 agatatatac tattataaag attgacgaag gcaacaattt aggagcagct aagataagga
    11881 tgaggtcctt aaaagcagct atgtttgaga gagaaagcaa aaatatagat gtaaaaaata
    11941 taaaggtaaa caggatacag tatgctaaaa ataatcagat aacgaacaaa catactatat
    12001 tagcaccaca aatgtctcca atacatttcc aattccttga aaaagctgtt aacttaagtg
    12061 gttataatat agaaattcta aaagatactg atagtagtgt aattgaagaa gggttaagat
    12121 atgtaaataa tgatgcatgt tatccagcta taatagttgt aggtcagcta ataacagcat
    12181 taaaatctgg caaatatgat ttaaataaca cttctgttac tataactcag actggtggag
    12241 gttgtagagc tacaaattat attggattct taagaaaggc tatatacgat gctggattta
    12301 aagatattcc tgtcattgca cttagtgtaa atggaataga agatagtggt ataatggata
    12361 atatatcact aaaattaatc aatagactct ttatgtctgt tgtttatggt gatttgctga
    12421 tgaaagtact atatagagta agaccatatg aaaaagttac tggaagtgca aatgctctat
    12481 atgaaaaatg ggttgatata tgcaaatctt ctcttgttaa agcaaaaatt tctgtattta
    12541 ctagaaatat aaaagatata gtaaaagaat ttgataattt agagatacta gatatcaaaa
    12601 aaccaaaagt aggtttggtt ggagaaatat tggtgaaatt ccatccaatt gcaaataata
    12661 atttagtaga tatattagag cgagaaggtg ctgaagcagt cgtgccagac cttacaaatt
    12721 tcttcttaag ttgtgccttt aatactatat acaaacacac tcatttagaa ggaagtagaa
    12781 agagtagaat gataggagaa gcatttatat acataactgg aatatatcaa agagtatata
    12841 aaaaagcact tgataagagt gagagatttt atgctccagc caatataaaa aatgttgcta
    12901 aaagtacaga accagtagtg tcattaggta atcaaactgg agaaggttgg cttttaacag
    12961 gtgagatggt tgaattatta aatgaaggtg tagaaaacat tatttgtatg caaccttttg
    13021 gatgtttacc taatcacata attggtaagg gttctataaa agaattaaag aggttgtata
    13081 aaaatgcaaa tataatacct attgattatg acccttctgc aagtgaggta aatcaactta
    13141 acaggataaa acttatgctt tctaaggctt ttaaaaatat ataagattta tattttgata
    13201 tgttaaaagt taatgaattt aaaaatatac tctatattaa gtatctataa aaaagagtta
    13261 tcctattttt tagggtaact ctttattagt taaaaaatta tatgtatact gatattaaag
    13321 gggggaagta atatgagttt agtatatgat gtttataaat caaaattagg aaatttgtac
    13381 atattaagtg aagatggttt tatagttagt atatacatag gagatgaaaa atttaataat
    13441 ttaaaaaatg aatgtattaa aaaaggaatt gatataaaga gaagtaagga agatttaaag
    13501 gaagcaataa gccagataga tgattacttt aatggaaaaa gaaaagtctt taatttaaat
    13561 attcgtattg aagggactga atttcaaaaa tcagtttata gggaaatgtt aaaaatacct
    13621 tatggagaaa cattgtgtta ttcagatata gcaagaaata taaacaatcc aaaatcagta
    13681 agagcaatag gacaagcaag taaaagtaat aaaattccaa taataatacc ttgtcataga
    13741 gtagttggca aaaaagatat tggtggatat atggggaatc attctgattt gaaagagata
    13801 ctattaaatt tagaaagaca gagttaactt agaaagaaat gtttttattg ttaatatttg
    13861 atataataat agtaaaaaga agtatttttt acaaaaacaa tgaagaattt attttaattt
    13921 ataaaaatga gggggaattt taatgtgtga taaagttata gcatcaaaat atcatgagaa
    13981 gggatttaat tgtgcagaat cagttataaa agcatataat gaggaattta atacagatat
    14041 accagtttgt ttaggaagtg gactgggttc agggtgtggg gttgctagtt tatgtggtgc
    14101 agtaaatgca tcaaatataa taattggata tgtaaaaggc agaaaccacg aagatgaaag
    14161 tactaaagct aaagtatatg ctaaagattt aactacaaca gtaagaaaag agtatggttc
    14221 agagttatgt atagacctaa aaaaagattt agttgcttgt agagaaataa tggatttcgc
    14281 atatgatagt ctaaaggaaa ctttaaaaaa agaattataa gaaaataagc tatcaagtat
    14341 aaattatttg atagcttatt tttatagtcg atactaaata aatcaaatat attttagaat
    14401 tattatttgt aaataaacag caaataattt taggattttt atttaatata gtttttattt
    14461 atatttattt ttgaatatgt tatactttgt ttaaataaat atttgtaatg agggagatga
    14521 gaagattgaa gaatctcaat ttacttatta ataaattata ttcaaaaaat cataatgaag
    14581 catataaaac ttttttattc ttagaaaatg aaagtttaaa atcaaatatt acatattgtt
    14641 tttttgactc attcctagaa atgattgata acgaaaactc atatattcga acaaggggat
    14701 tgttattaat ctctgcaaat gctcagtggg atattgataa taaaattgaa ataaatatag
    14761 atagtatact aagtcatatc gtagataaaa aaccttctgt atcaagaatg tttattaaat
    14821 ccatacctaa tattacaaag tataaagaaa atcttattaa tcgcataaaa atggaattaa
    14881 gtaatgcaga tataagt
//
LOCUS       DAEPHU010000093        14510 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 01A10CD0081
            SAMN05941466-rid12468953.denovo.093, whole genome shotgun sequence.
ACCESSION   DAEPHU010000093 DAEPHU010000000
VERSION     DAEPHU010000093.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941466
            Sequence Read Archive: SRR6291087
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 14510)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14510)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068158.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 22:43:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,892
            CDSs (total)                      :: 3,805
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 87
            rRNAs                             :: 8, 1, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 55
            CDSs (without protein)            :: 55
            Pseudo Genes (ambiguous residues) :: 0 of 55
            Pseudo Genes (frameshifted)       :: 21 of 55
            Pseudo Genes (incomplete)         :: 28 of 55
            Pseudo Genes (internal stop)      :: 16 of 55
            Pseudo Genes (multiple problems)  :: 8 of 55
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14510
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941466-rid12468953.denovo.093"
                     /strain="01A10CD0081"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            231..1310
                     /locus_tag="KR231_003248"
     CDS             231..1310
                     /locus_tag="KR231_003248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895654.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA alkylation repair protein"
                     /protein_id="HBH0005588.1"
                     /translation="MPELLKNMYNRESLYEVAVAIQSVYNSFKVDEFIKSTMDETWNN
                     LELKARCRKISMSLGMYLPEDYKEALSILEKSVTGFYFAFFFPDFVEVYGQDDINWDL
                     SISALERNTEYWSSEFAVRAFIIKDEERMMAQMRKWSKHKSEHVRRLASEGCRPQLPW
                     GQAISKFKKDPTPVLPILEQLKTDTSTYVQKSVANNLNDISKTHPDLVISIAKDWYGK
                     NKSTNWIVKHGCRTLLKKGNRDVLALFGYDDTTSINLQDFTLETTSISIGEDLTFSFN
                     ILAKKATKTRLEYGIDYIKSNGKRNRKIFKISEVSLKENEKKSYMKKHSFADVSVRKH
                     YPGIHSIAIIINGIEKDKLDFELGI"
     gene            1634..2002
                     /locus_tag="KR231_003249"
     CDS             1634..2002
                     /locus_tag="KR231_003249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nuclear transport factor 2 family protein"
                     /protein_id="HBH0005589.1"
                     /translation="MDVYSFWNDTLAQDAVKIRKYFHENAYINWHDTNEHFTLEEFII
                     ANCEYPDKWNGKVEKVLEFGNLVITVTHVYAINKPLSFHVVSFISLKDDKIISIDEYW
                     GEDNDVPQWRLDKHIGKPIK"
     gene            2119..2922
                     /locus_tag="KR231_003250"
     CDS             2119..2922
                     /locus_tag="KR231_003250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HBH0005590.1"
                     /translation="MEEKYILSDRGKVYYWIKESNSVFAKNLIFLPGLTANHHLFDFQ
                     IQYFSKNHNVLVWDAPAHGKSRPYLDFSYSNLVEELKVILDKQNMKKVVLIGQSAGGF
                     VAQSFIVKYPNMVEGLMMIGTCPYGTDYYSKSDIFWLKQTEWMLKLFPDKFLRNIISK
                     MCGATSEGRRSMMKMLEGYEKKELCHLMYLGFAGFIPEIQDLNIHCPVCLVVGDKDKT
                     GKVRKYNEQWHNKTGYPLHIIKNASHNVNVDKPNELNQIMDIFIKQLNI"
     gene            3307..4197
                     /locus_tag="KR231_003251"
     CDS             3307..4197
                     /locus_tag="KR231_003251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902047.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM protein"
                     /protein_id="HBH0005591.1"
                     /translation="MIESIPAKQILQKVKFDNTRWFGIDYNMNLYRGCSHGCIYCDSR
                     STIYNIENFDKVRYKENVIEILSKELRSKRKKGVVGIGAMSDTYNPFEKQLCITKQAL
                     DLISENHFGVSIDTKSSLVVRDIPILQKIKKNNSAIVKLTITTANDELSKKIEPYVNP
                     SSVRFEAVKELNDSGIFCGILLTPMLPFLTDTKDEIRAIVEKAHKANAKFIYCMYGVT
                     MRSGQREFFYEHLRDISPKLVFKYQKTYGLNYVCTVQNKDCCEKLLREECARYGILTD
                     MKDIIKAYKRSESYTQIKFF"
     gene            4760..5203
                     /locus_tag="KR231_003252"
     CDS             4760..5203
                     /locus_tag="KR231_003252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBH0005592.1"
                     /translation="MIEIKTIEINKKSQIDLLILADPCEEMIDKYLNKGTMYALYDNK
                     ELTCIAVVNEISKEICELKNIATYEHFQNMGYASKMIYHLLDVYSKKYSSMVVGTSES
                     GVPFYEKFGFVYSHKIKNFFVDNYPEPIFEGELQCVDMLYLSYNF"
     gene            5375..5545
                     /locus_tag="KR231_003253"
     CDS             5375..5545
                     /locus_tag="KR231_003253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0005593.1"
                     /translation="MDSNNNTIKSTVKKGISFGSCLAMIISYTAWKSIPWAIFHGLMS
                     WIYVLYYWVKYA"
     gene            5918..7039
                     /locus_tag="KR231_003254"
     CDS             5918..7039
                     /locus_tag="KR231_003254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rpn family recombination-promoting
                     nuclease/putative transposase"
                     /protein_id="HBH0005594.1"
                     /translation="MKEKLEEKSKIIKTSKEYKRTIIEEKDREWTQKLNDILSRGDFS
                     NEKLDKIKDLIPKEILTSENVGEVVTEDGYAKPEYDEVFKSLFTLNNDYDLLANFIND
                     ILKDAPYANRNIKQFTQIKRIIKVETDPTINYIGEKRPRLDILAEDEERNHINIEMQR
                     ALEEDYLERAEYYLSRVHGRKLEEGKEYKEIGKTVGIHILNHVKYNHIEDYVNCLRLT
                     MDGHPDIFSSKTALYFIELPKIRKSSCIANRVLIWGKLIDNPSHIDIRILSKTDYVIK
                     RALDRLKELGSNEDYLLNLKRGAYIMNKSRNFKEEIFQEGIEKGIEKGIEKGIAKGKR
                     EEKFNIIIKLKNKGYNLSEICDIIDDLNKSEVEKVYNQN"
     gene            7244..7732
                     /locus_tag="KR231_003255"
     CDS             7244..7732
                     /locus_tag="KR231_003255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3841 domain-containing protein"
                     /protein_id="HBH0005595.1"
                     /translation="MKFYTIQTLEFWNNNKNNKYLSNDYSFILEDFDIPYKWMYSQMT
                     NRIYEFDDSMIWVWTKRPDLRCSGYLEKGKKGVLLEIEISEDNVLLSEFDLWHLPLMD
                     ITVELYEDEQIEKKVSWERIFDLELCSKLNEVNIEDLTLQGVTSKVPLSNVKLIKEFV
                     AK"
     gene            7818..8225
                     /locus_tag="KR231_003256"
     CDS             7818..8225
                     /locus_tag="KR231_003256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0005596.1"
                     /translation="MSKQQTGIKSTLISEILGISYCIGATLVNKYFFKGSSIEYLPII
                     IWVLAMGAQWVYNKKYDDLIDEASKCILSRVNDIAIKVLFFSVAIVSIFLVTLDINVS
                     NLNIGMSLLVILFIQSLLKLILFIYFDRKGIYN"
     gene            8226..8444
                     /locus_tag="KR231_003257"
     CDS             8226..8444
                     /locus_tag="KR231_003257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBH0005597.1"
                     /translation="MSVLLKTKIKSYREKNLMTQGELAKSVGVRRETIVHLENGRYNP
                     SLKLAMDIAKVFDTTVEELFEFIEENNI"
     gene            9518..9813
                     /locus_tag="KR231_003258"
                     /pseudo
     CDS             9518..9813
                     /locus_tag="KR231_003258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427875.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            10221..10910
                     /locus_tag="KR231_003259"
     CDS             10221..10910
                     /locus_tag="KR231_003259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBH0005598.1"
                     /translation="MDILLVEDDKNIREMVYDFLISENYSVKTAIDGNTAIEIFKNYS
                     FDIILLDLMLPKSSGFEVLKYIRSVSVVPVIITTAKDSDTDKMLGLNLGADDYITKPF
                     SIVELLARIKANIRRATVYSSSRNSQDMVIRYKDLIINISKYVVSKNGIDLNLTHTEF
                     EIVKLLATNQGRAFSKEQLYNAIWKEPYYGNENVLNTHINRLRNKLSDGIEKNNYIKT
                     LWGIGYKMEEE"
     gene            10910..11827
                     /locus_tag="KR231_003260"
     CDS             10910..11827
                     /locus_tag="KR231_003260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HBH0005599.1"
                     /translation="MELFLVVISIVLFALYLKERNKSKKMESDYKYINSRLRDITNDD
                     EINYILVPSDISIVKETAVDINKLVEKFYSRQINYNRSEKAILQIFTNISHDLRTPIT
                     VLKGYIEMLYLQSQKEELSSSMRAIVEKMQTNSNELVNSINNLFNMAKIQSGDMILNL
                     QKSNLTQLCHEIILEFYDLLDKENFNVEVNIEDRPIYANVDTEALQRILKNLIDNAIK
                     YGSDGRFLGISLYEKEKHVFIDIEDKGSGISETEKEHIFTRAYTADRKKGNGLGLAIS
                     QGLANSMGGSIYVNSRPNVKTVFTVKLKS"
     gene            11900..12826
                     /locus_tag="KR231_003261"
     CDS             11900..12826
                     /locus_tag="KR231_003261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH0005600.1"
                     /translation="MNYIIETHQLKKIYKDKAVVNAVNIHVKKGEIYGFVGPNGAGKS
                     TVMKMLLNLVNPNSGEIVMFGKKVAETDFEILKKIGTIIENPYLYENLTAKQNLDLHC
                     EYMGYYNKEHISEVLECVGLSKQSNKKVSKYSLGMKQRLAIARAILTKPELLILDEPI
                     NALDPEGIREMRELFRKLNTDYGITIFISSHILSEVEQIADTIGIIQDGKLIKEISMS
                     DIHKYQTDYVEVDVDNVELAGYLLEKEFGIKDFKITSESCIEIYDLRKDVKEISKIFI
                     QNQIGINSIGRKQSSLEDYFFQTTGTGGKETL"
     gene            12823..13503
                     /locus_tag="KR231_003262"
     CDS             12823..13503
                     /locus_tag="KR231_003262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBH0005601.1"
                     /translation="MIHLMKLELKKVGLKRYFLFSMLGIFLCMFFVFTGLNDKSTSIY
                     DYDVTFRTISLFFCFYYIILFAVLNVAYIINEYTNKTILILFSYPLDRKKLILSKLLL
                     ITTLMISSMIVGYICCFTFVVVLDKYFNLVIGDFHISILSYWIPGAIKSIIVFCSLGI
                     WTFVVGMIRKSIPVTLVSSIIFINLRQFILAGTNTTQDSLISVFIIVGITVIGIYYIL
                     NHKVTEID"
     gene            13601..13936
                     /locus_tag="KR231_003263"
                     /pseudo
     CDS             13601..13936
                     /locus_tag="KR231_003263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427885.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="Fic family protein"
BASE COUNT         5723 a         1426 c         2436 g         4925 t
ORIGIN      
        1 cagtaaagta taaaattcta ttactataat aaaagataga actagaagtc tttatgaaag
       61 tgggaaaagt atttatataa ataaattcat atagtttata gtttaatagt aggaaatatc
      121 gtatgagtaa gaatattgta ttttacataa agatttagca atatgacaca ctgttgtcgt
      181 gttctgtagg atatgattaa taaatcagat atgaaaggag agtgagtaat atgccagaat
      241 tactaaaaaa tatgtataat cgtgagtcac tttatgaagt tgcagtagct atccaatcag
      301 tttacaactc atttaaggta gacgagttca taaaatctac aatggatgag acatggaata
      361 acttagaatt aaaagccaga tgtcgaaaga taagcatgag tttaggaatg tatttaccag
      421 aagactataa ggaagctctt tccattcttg aaaaatcagt tacaggtttt tattttgctt
      481 ttttctttcc agattttgtt gaagtttatg ggcaggacga cataaattgg gatttatcta
      541 taagtgcatt agaaagaaat actgagtatt ggtcttcaga atttgctgta agagcattta
      601 tcatcaagga tgaagaacgt atgatggcac agatgcgtaa atggtctaag cataagagcg
      661 aacatgtacg aagacttgca agtgaaggtt gtcgtcccca gttgccttgg ggacaagcaa
      721 tatccaaatt taaaaaagac cctacacctg tgctacctat attggagcaa cttaaaacag
      781 atacatcaac gtatgtacaa aagagtgttg ctaataatct aaatgatatc tcaaaaacac
      841 atccagattt agtcataagc attgcaaagg attggtacgg taaaaataaa tctactaact
      901 ggattgtaaa gcatggttgt agaactctac taaaaaaagg aaatcgtgat gtattagccc
      961 tttttggata tgatgatact acttctataa atcttcagga ctttacttta gaaacaacgt
     1021 ctatttctat tggagaggat ttaacttttt catttaatat tttagcaaaa aaagcgacaa
     1081 aaacaaggct cgagtacgga attgattata ttaaatctaa tggaaaaagg aataggaaga
     1141 tatttaaaat atcggaggtt tcattaaaag aaaatgagaa aaagtcatat atgaaaaaac
     1201 attcatttgc agatgtaagt gtaaggaaac attatccagg tatacactcg attgctatta
     1261 ttattaatgg tatagaaaaa gataaacttg attttgaatt aggtatataa ttttactaac
     1321 agaataatct atatcagata ctttgctaaa cttatataat atattttact aaatttatat
     1381 taggtagttt actacttgtt tactgaattt aaatacaaag aaatacaggt gctaatccct
     1441 gcccattaaa ggaatatgag cataacacaa aagtagaact tatcaattct gttacgggta
     1501 tagtagtaaa tccatagaat cacaattaga agatgaagtg taaaaaataa gttagtgttg
     1561 attttagttg ctagtgatat tgaatagtta tacaatagct atataaatta gaatttgtag
     1621 aggagaaatg taaatggatg tatatagttt ttggaatgac actttagcac aagatgctgt
     1681 taagataaga aaatattttc atgaaaatgc ttatattaat tggcatgata caaatgagca
     1741 ttttacttta gaagaattta ttattgcaaa ttgtgagtat cctgataaat ggaatggtaa
     1801 agtagaaaag gtgctagaat ttggaaattt agtaattaca gtgacacatg tttatgcaat
     1861 aaataaacca ctatcatttc atgtcgtttc atttatcagc cttaaagatg ataagattat
     1921 ttctattgat gaatattggg gagaggataa tgatgtgcca cagtggagat tagataaaca
     1981 tattggaaag ccaataaaat agtttttgtt ctgttttata actgaaattt tgataacatt
     2041 tgatattttg atttgtcatt ggtcaacata gtcgttagtg taataattta aaaaagtaga
     2101 atttggagag tgaacactat ggaagaaaaa tacatcttat ctgaccgagg gaaagtatat
     2161 tattggataa aagaaagtaa tagtgtgttt gcaaagaact taattttttt gccaggacta
     2221 acagcaaatc atcatctttt tgatttccaa atacagtact tttcaaaaaa tcataatgta
     2281 ttggtatggg acgctcctgc tcatggaaaa tcaagacctt acttagattt ctcatattct
     2341 aacttggtag aagaattgaa agtaatttta gataaacaaa atatgaaaaa ggttgtactt
     2401 atagggcaat cggcaggggg atttgtggca cagtccttta ttgtaaaata tccaaatatg
     2461 gtagaaggac taatgatgat tggaacttgt ccatatggaa ctgactatta tagtaagtca
     2521 gatattttct ggttaaaaca gactgaatgg atgttaaagt tattcccaga taaatttttg
     2581 cgaaacataa tatctaagat gtgtggagct acgtctgaag gcagaaggag tatgatgaaa
     2641 atgttagaag gctacgaaaa aaaagaactg tgtcatctca tgtatctggg atttgctggg
     2701 ttcataccag aaattcaaga cttaaatata cattgtccag tttgtttggt ggttggagat
     2761 aaagacaaga cgggtaaagt gagaaaatat aatgagcagt ggcacaacaa gactgggtat
     2821 ccattgcaca ttataaaaaa tgcttcacat aatgtaaatg tcgataaacc taatgaacta
     2881 aatcagatta tggatatatt tattaagcaa ttaaatatat aaaaattaca tactcattag
     2941 gtaaattatg tagtatatgt gtttatagat ggttatagaa ataaatatgt aataaactac
     3001 ttaacactta aaaagtggat ttgtccagag cataatacaa agcatgatat ataaattttt
     3061 aagcgaaata catcaaaaga agtattagaa ttagtggaga taaaacagct attagagatt
     3121 ataaataaat agttttaaag gtactacgaa tatagaggaa ggtaaatcat acgttattca
     3181 aggattataa atgattagtt taaaagtact atcggacagg tctctgcata tttaaacctt
     3241 agtaaaggta gttaaagtag tagtttaaaa actaaaaaat tatataaagg aattaggtat
     3301 aagaaaatga ttgagagtat accagcaaaa caaattttac aaaaagtgaa atttgacaat
     3361 acaagatggt ttggaattga ctataatatg aatctctatc gtggttgttc tcatggatgt
     3421 atatattgtg atagccgtag cacaatatac aacatagaga attttgacaa agttagatat
     3481 aaagaaaatg tgatagagat tttaagtaaa gaattgcgtt caaaaagaaa aaaaggggta
     3541 gtaggcattg gagctatgtc tgacacatat aatccttttg aaaagcaact ttgtattaca
     3601 aagcaggcac tagatttgat ttcggaaaat cattttggag tgtctattga tactaaaagt
     3661 agtttggtgg ttagagatat accgattttg cagaaaatta aaaaaaataa ttctgctatt
     3721 gtaaagttga ctataaccac tgcaaatgat gaattatcaa agaaaataga accttatgta
     3781 aatccaagtt ctgtacgatt tgaggcagtg aaagaactta atgattctgg aattttttgt
     3841 ggtatattat tgactcctat gcttccattt ttgactgata ctaaagatga aatacgagca
     3901 attgtagaaa aagcacacaa ggctaatgca aaatttattt attgtatgta tggtgtaaca
     3961 atgcgtagtg gtcagcgaga gtttttttat gagcatttaa gagatatatc accaaaattg
     4021 gtatttaaat atcagaaaac atatggttta aactatgtat gtactgtaca aaataaagat
     4081 tgttgtgaga agttgttaag agaagaatgt gcacgttatg gtattttgac ggatatgaaa
     4141 gatattataa aagcgtacaa gaggtcggag tcatatactc aaataaaatt tttttaagat
     4201 aggctttgga tgagatataa tagtggtgat tgatgtgttg atattatagt tgattgttag
     4261 agaggatatt atagatgaat attagtatta atattttagg taattgctag agctgatatt
     4321 atagatgaat attaatattg atattctagg taattgctag agttagtatt atagatgaat
     4381 attagtattg atattttagg taattgctag agctgatatt atagatgaat attaatattg
     4441 atattctagg taattgctag agttagtatt atagatgaat attagtattg atattttagg
     4501 taattgctag agctgatatt atagatgaat attaatattg atattctagg taattgctag
     4561 aactaatatt atagatgaat attagtattg atattctagg taattgctag agctgatatt
     4621 ataatttatt attaatatta atattctagg gaattatcac tatattttaa aaagtaaaaa
     4681 tatatatcaa aatgaactaa ataagtactg taagaagttt gttaaattaa ggtttgaata
     4741 aagtgagggt ggagaactta tgatagaaat aaaaactata gaaataaata aaaaaagtca
     4801 aattgacctt ttaatattag ctgacccatg tgaagaaatg attgataaat atctcaataa
     4861 aggaactatg tacgcattgt atgataataa agaacttact tgtatagcag ttgtaaatga
     4921 aatttccaaa gaaatatgtg aattaaaaaa cattgctaca tatgagcatt ttcaaaatat
     4981 gggttatgcc tcaaagatga tttatcatct tttagatgtt tatagtaaaa aatattcatc
     5041 aatggttgtt ggtacatctg aaagtggagt tcctttttat gagaagtttg gatttgttta
     5101 ttcacataaa attaaaaact tttttgtaga taattatcca gaaccaatct ttgaaggaga
     5161 attacaatgt gttgacatgt tgtatctatc atataacttt tagataggat aatattttta
     5221 ggttaatata attaattaat tcatataatt atcggaatta taatttataa attatgtata
     5281 ataagagtat aatttattta gaagctgtta tattgtatta gattcaaata agatatataa
     5341 taacttgttt attttgaatt ttggaggatt aattatggat tcaaataata atactataaa
     5401 atcaactgtt aaaaagggta tttcttttgg ttcttgttta gcaatgatta tttcttatac
     5461 tgcatggaaa tctattccat gggctatttt tcatggctta atgagttgga tatatgtact
     5521 ttattattgg gttaagtatg catagattaa attaataaat aagtatgtaa tattgtaaag
     5581 tttaagaaac aaaatgtaag ggagtgtctc gaagtgaact tttagtttat aaggcactct
     5641 tttttgtatt aaataaaata tattttcatt acttaaacaa tgaaaaagat gagtatctct
     5701 attttaatac atacccttat attcattcat ttatcaacaa tagttttaaa aagaaagcta
     5761 tctaaaatct attgtaatct aagtgcttct ctttaaagtc ttaactttag taatgatata
     5821 taagtttata aggttcttat ttcaataatg caaattttac ttagaagttc agactttggt
     5881 atgaagaaat gggtaataat aaaaaagagg tgttgatatg aaagaaaaat tagaagaaaa
     5941 atctaagatt attaaaacat caaaagagta taaacgaact ataattgaag aaaaggacag
     6001 agaatggacc caaaaattaa atgacatact tagtagaggt gatttttcta atgaaaaatt
     6061 agataaaatc aaggatttaa ttccaaaaga aatattgact agtgaaaatg ttggagaagt
     6121 tgtaactgaa gatgggtatg ctaagcctga gtatgatgag gtatttaaat cattgtttac
     6181 tttaaataat gattacgatt tacttgcaaa ttttataaat gatatcctca aagatgctcc
     6241 atatgctaat aggaatatca aacagttcac tcaaataaaa agaataatta aggttgaaac
     6301 cgacccaaca attaattaca ttggtgagaa aagacctaga cttgatattt tggctgaaga
     6361 tgaagaacgt aaccatataa atattgagat gcaaagagct cttgaagagg attatttgga
     6421 aagagctgaa tattatctta gtcgtgtaca tggtagaaag ttagaagaag gtaaagaata
     6481 taaagaaatt ggaaaaactg ttggaataca tatactaaat catgtaaaat ataatcacat
     6541 agaagattat gtaaattgcc tgagattaac aatggacggg catccagata ttttttctag
     6601 taaaactgca ttatatttta tagaacttcc aaaaattcgt aaatccagtt gtatagcaaa
     6661 cagagttcta atatggggta aacttattga taatccttct catatagata ttagaatact
     6721 atctaaaacg gattatgtta ttaaaagagc acttgataga ttaaaagaat taggtagtaa
     6781 tgaggactat ttattaaatt taaagagagg tgcgtatatt atgaataaaa gtagaaattt
     6841 taaagaagaa atttttcaag aaggtattga aaaaggtatc gaaaaaggta tcgaaaaagg
     6901 tattgcaaaa gggaaaagag aagagaaatt taatatcatc ataaaattaa aaaataaagg
     6961 atacaatttg agtgaaatat gcgatattat agatgatttg aataaatcag aggttgaaaa
     7021 agtctataat caaaactaat actatgattg agatggcact agataaatac aaagcttcct
     7081 cttttaaatt taaattaata taaaactttg ttatttaaat atggtagata taaagagata
     7141 tataaataat aggtacaaag aggtgtataa ataaaggaga taattcaaaa taaaagtttg
     7201 aaccatctcc ttcttataga aaaacaaagg ggttgattta tatatgaaat tttatactat
     7261 acagacttta gaattttgga ataacaataa aaacaataaa tatctatcaa atgattattc
     7321 ttttatatta gaagactttg atattccata caaatggatg tatagtcaaa tgacaaatag
     7381 aatatatgaa tttgatgata gtatgatatg ggtttggacg aagagacctg atttaagatg
     7441 tagtggttat ttagaaaaag gaaaaaaagg tgttttactt gaaatagaaa taagtgaaga
     7501 caatgtgtta ttatcagaat ttgatttatg gcatttacct ttaatggata ttactgtaga
     7561 gctttatgaa gatgaacaaa ttgaaaagaa ggtaagttgg gaaagaatat ttgacttaga
     7621 actgtgttca aaattaaatg aagttaatat agaagatttg acattgcaag gagtgacatc
     7681 taaagtgcct ctatctaatg taaaattaat aaaagaattt gttgcaaaat aatattttta
     7741 ttgaaattta ttcaaaaaag ttatatattt ataacaagag gtgttataaa tacataactt
     7801 tttaaggggg attttatatg tctaaacaac aaactggtat taaatcaaca cttatttcag
     7861 aaatattggg aatttcttat tgtattggag ctacattagt aaataagtat ttttttaaag
     7921 gaagtagtat tgaatatctt cctataatta tttgggtatt agctatggga gctcagtggg
     7981 tctataataa aaagtatgat gatttaattg atgaggcatc aaaatgtata ctatcaagag
     8041 ttaatgatat tgcaataaaa gtattgtttt tttctgtagc tatagtatct atatttcttg
     8101 taactttgga cataaatgtg tcaaatttaa atataggaat gtctttatta gtcattttgt
     8161 ttattcaatc cttgttgaag ttaattctat ttatatattt tgacagaaag gggatataca
     8221 attaggtgtc agtattacta aagacaaaaa ttaaatccta tagagaaaag aaccttatga
     8281 cacaaggtga acttgcaaag tcagtaggag taagacgtga aactattgta catttagaaa
     8341 atggtcgcta caatccttct ttaaaactgg caatggatat tgctaaggta tttgatacaa
     8401 ctgtagaaga gttgtttgaa tttattgaag aaaataatat ttaaatttca tgtattactt
     8461 atgcattaga gaatgaatta attataggta aaaaaccaag cttatagatt agagaataaa
     8521 tgacttatag atgaaaaacc aagctaatgg attaaagagt gaatgattta tagattaaga
     8581 agtaagctta tagattagag aataaatgac ttatagatga aaaaccaagc taatggatta
     8641 aagaatgaat gatttataga tgaaaaagaa agcttataga ttagagaata aatgacttat
     8701 agatgaaaaa ccaagctcat agattaaaga atgaatgatt tatagatgaa aaagaaagct
     8761 tatagattag agaatgaatt aattataggt aaaaaacaag ctaatagatt aaaaaatgaa
     8821 tgatttatag attaagaagt aagcttatag attagagaat aaatgactta tagattaaga
     8881 agtaagctta tagattagag aataaatgac ttataaataa aaaccaagct tatagattag
     8941 agaataaatg acttataaat aaaaaccaag cttatagatt agagaatgaa ttaattatag
     9001 gtaaaaacca agcttataga ttaaaaaatg aatgatttat agatgaagaa ctaaacttat
     9061 agattaaaaa ataaatgact tatttataga tgaaaaacca aacttataga ttaaaaaata
     9121 aatgatttat agatgaagaa ctaaacttat agattaaaaa ataaatgact tatagatgaa
     9181 aaatcaagct catagattaa agaataaata acttattaga tgaaaaacca agcttataga
     9241 taagaagtcc atgcttataa gccagaaaat gaatagttta atagattaaa aaatacatat
     9301 ttgtgaatta tagaatgaat aactccataa actagaaaat ttataataat atctatatga
     9361 aaattagaat tattttatca caaaaaaatt aagttaaata aatatgaaat tacttccaaa
     9421 tatacttcca aaaacatgta atcgcatata taatataatt ataaaaataa taaatatttt
     9481 tatagtagta gttaattatt aataaggagg ggtcaaaatg cctagcatga ttatggaagt
     9541 tgtaggagta ctatttatag ctattggatt aatcttgaca ttcattgaaa taaaaggaaa
     9601 tttcccttct ttttatggtt ttggtcaaaa ttaaaatgct gtaggtatta tagcagcagg
     9661 aattgcttta attttcttta gaaatggcat agatacatag attctatagc tacttatggt
     9721 gtatttttag caatagaact tgttgtaata gttgcatatt tcttaataag aaaaaaattt
     9781 actaaagaag ataaacattt aagaactaat taactaaatt atctactata aaattggaaa
     9841 attaaaaaca aataaaagtt tgtttttaat tatttaaaat ccaaatttga ttatttttaa
     9901 agaaactatg ttctgtataa aactagaatg tggtttcttt tttatgtata aaatattttt
     9961 tagcaaaagt taaaaggtgt tttataatat aaaatagtta attgtagatg ttaataaaag
    10021 aaaattatgt atattttaga taaagataag agagtatact atattttaat tcttttttca
    10081 ataaagctta ttgaaaagaa ctttaactta gaagagtatc accaaattgc agatacaata
    10141 tcataagcag ttatttattg acaacccttt ttaataaata tatcatttga agtatactga
    10201 cgaaaaggag ttgaataata atggacatct tattggttga agatgataag aatattcgag
    10261 aaatggtata cgattttctg attagtgaga attactctgt taaaactgcc attgatggaa
    10321 atacagctat tgaaatattt aaaaattatt catttgatat tattttactg gacttgatgt
    10381 taccaaagtc tagtggtttt gaagtattaa aatatatacg aagtgtgagt gttgttcctg
    10441 ttattattac tactgcgaaa gatagtgaca cagataaaat gctagggctt aatctaggtg
    10501 cagatgatta tattacaaag cctttttcaa tcgtagaatt gcttgcaaga attaaagcta
    10561 atattagacg tgcaacagtg tatagcagtt caagaaactc tcaagatatg gttattcggt
    10621 ataaggattt gattataaac atatcaaaat atgtagtttc aaagaatgga attgacttaa
    10681 acttaacaca tacagaattt gaaattgtta aattactagc gactaatcaa ggacgtgctt
    10741 tttcaaagga acaattatac aacgctattt ggaaagaacc ttattatgga aatgaaaatg
    10801 tgctaaatac tcatattaac aggttaagaa ataaattgtc tgatggtata gaaaaaaata
    10861 attatattaa aactctttgg ggaattggct acaaaatgga ggaagaataa tggagttatt
    10921 tttagttgta atttcgattg tactatttgc tctctactta aaagaacgaa ataaatcaaa
    10981 gaaaatggaa agtgattata agtatatcaa ttcaagactt cgtgacataa caaatgatga
    11041 tgaaattaat tatattttag taccatctga tatttcgatt gtaaaagaaa cagcagtaga
    11101 tataaataaa cttgttgaaa agttttacag caggcaaatt aattataata gaagtgaaaa
    11161 agcgatattg caaatattta caaacatatc acacgattta cgaactccca tcacagtatt
    11221 aaagggttat attgaaatgc tatatcttca aagtcaaaaa gaagaattat cttcttcaat
    11281 gagagcaatt gtggaaaaaa tgcaaacaaa ttcaaatgag cttgttaatt caataaataa
    11341 cctgtttaat atggcaaaaa tccaatctgg agatatgata ttaaatcttc aaaaatccaa
    11401 tctaacacaa ttatgtcatg agattatttt agagttttat gatttgctag ataaagaaaa
    11461 ctttaatgtt gaagttaata ttgaagatag acctatatat gcaaatgttg acacagaagc
    11521 attacaacgt atactcaaaa atttaattga taatgctata aaatatggtt cagatggtag
    11581 atttttaggg atttcactat atgaaaagga aaaacatgtt tttatagata ttgaggataa
    11641 aggttcaggt atttctgaaa ctgaaaaaga gcatattttc acaagagctt atactgctga
    11701 cagaaaaaaa ggcaatggtt taggtttggc tatttctcaa gggcttgcaa actctatggg
    11761 aggttcaatt tatgtaaata gtagacctaa tgtaaaaaca gtttttacgg taaaattgaa
    11821 aagttagaaa aaagttagat ttaaaagaga gaaaagacaa ttttattttg tatactgttt
    11881 ttagaaagga gggagtatga tgaactatat catagagacc catcaattaa agaaaatata
    11941 taaagataaa gctgttgtta atgctgttaa tattcatgtg aaaaagggag aaatttatgg
    12001 atttgttgga ccaaacgggg caggtaaaag tacagtaatg aaaatgttgc taaatcttgt
    12061 taatccaaat tctggagaaa tagttatgtt cggtaagaaa gtggcagaaa ctgattttga
    12121 aatattaaaa aagattggta ctattattga aaatccgtat ttatatgaga atttgactgc
    12181 taaacagaat cttgatttac actgtgaata tatgggttat tataacaaag aacatatatc
    12241 agaggtattg gaatgtgtcg gattgtcaaa gcaatcaaac aagaaagttt caaaatattc
    12301 tttagggatg aaacaacgtc ttgcaatagc tagagcaatt cttactaaac cagaattatt
    12361 gattcttgat gaacctataa atgcactcga cccagagggg ataagagaaa tgcgagaatt
    12421 attccgtaag ttaaatacag attatggaat aactatattt atttctagtc atattctttc
    12481 agaggtagaa caaattgcgg acactattgg aattattcaa gatggtaaac ttattaaaga
    12541 aatttctatg tcagatatac acaaatatca aacagattat gttgaagtag atgtagataa
    12601 tgtggagctt gctggatact tgttagaaaa agaatttgga ataaaagact ttaaaattac
    12661 ttcggaaagt tgtattgaaa tatatgattt acgaaaagat gtaaaagaaa tatccaaaat
    12721 atttattcaa aatcaaattg gtataaatag cattggacgt aaacaaagtt ctttagaaga
    12781 ttacttcttc caaactacag gtacaggagg taaagaaaca ctatgataca tttaatgaaa
    12841 ctagagctaa aaaaagttgg gctaaaaaga tattttttat tttcaatgct ggggattttc
    12901 ttatgtatgt tttttgtctt tactggattg aatgataaat ctacttcaat atatgattat
    12961 gatgttacat ttaggacaat cagtttattt ttctgttttt actatattat attatttgct
    13021 gtgttgaatg tggcatatat aataaatgaa tatacaaata aaacaatctt gattttattc
    13081 tcttatccac ttgaccgtaa aaaacttatt ttatcaaagt tacttttgat tacgactctt
    13141 atgatatcat caatgatagt tggatatatc tgttgtttta cattcgttgt tgtgttggat
    13201 aagtatttta atttagttat tggagatttt catatttcaa ttttatctta ttggatacca
    13261 ggagcaatta aaagtattat tgtattttgc tcattaggta tatggacatt cgttgttgga
    13321 atgataagaa aatcaatacc tgttaccctt gtcagttcaa ttatttttat caatttaaga
    13381 caatttattt tagctggtac aaatacaact caagacagtt tgatttctgt ttttattata
    13441 gttggtataa ctgtgattgg tatatattat atactaaatc ataaagttac tgaaattgac
    13501 tagatactgt ggataggagg gtagttatta attgtatctt cttgggataa taatgatttg
    13561 ctattatatc agctattatt aatattatta gagttttaat aatattgcac aaccatttga
    13621 agttgagcca aagcttgatg aattaattga atggtactat agtcagagtg aagtatctat
    13681 taaagttata gctgaatttc attatagatt tgaattgata catccatttc aagatggtaa
    13741 tggtcgcata ggtagatttg ttatgctaaa acagatgtta gaaaataatc ttcctataaa
    13801 aattgtatct tgggatagtg aggaattgta tagaaactcc ttaaattctt gtagtttagg
    13861 taattatgtc cctttaattg aatatttatc aagtttagaa gattttagag aagtatataa
    13921 aatgttatgg aaataattgt ttgcagcaaa aaaagttttt atataaatat atttttatct
    13981 atgctattta acgctaattt cttagttatt cttagcttgg actataccca ctattttaac
    14041 tatataaaat agtggatata gtttaactat ctctttataa ctatttttat gtatcttagt
    14101 tgtttcttaa tatggggaca gttcataaaa ctaaaagtga tttttaattt tatcatttat
    14161 aatttaccat tacatcagaa aaatgcttat cattagaatt ttcataaaag gtacctattt
    14221 ttttcaatta actgaatcaa ttctattagt cttaatcttt catatttcaa attgataata
    14281 taagaaaata aaaaataaaa aattttaaat tttttattta ttgcgaaaaa aataaaaagg
    14341 tgctatactt tttgtaacat attattcaaa ttattaagag atagtaaaca tttatagttt
    14401 aatttgtagt acactagcat gatttgcaga acaatgaatt aatctatagt ataatagttt
    14461 aatttaaagt acaacgattt aatctatagt acactagcat gatttgaagt
//
LOCUS       DAEPHU010000094        14104 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 01A10CD0081
            SAMN05941466-rid12468953.denovo.094, whole genome shotgun sequence.
ACCESSION   DAEPHU010000094 DAEPHU010000000
VERSION     DAEPHU010000094.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941466
            Sequence Read Archive: SRR6291087
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 14104)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14104)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068158.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 22:43:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,892
            CDSs (total)                      :: 3,805
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 87
            rRNAs                             :: 8, 1, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 55
            CDSs (without protein)            :: 55
            Pseudo Genes (ambiguous residues) :: 0 of 55
            Pseudo Genes (frameshifted)       :: 21 of 55
            Pseudo Genes (incomplete)         :: 28 of 55
            Pseudo Genes (internal stop)      :: 16 of 55
            Pseudo Genes (multiple problems)  :: 8 of 55
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14104
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941466-rid12468953.denovo.094"
                     /strain="01A10CD0081"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            complement(<1..1229)
                     /locus_tag="KR231_003264"
     CDS             complement(<1..1229)
                     /locus_tag="KR231_003264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF262 domain-containing protein"
                     /protein_id="HBH0005602.1"
                     /translation="MKAGEIEFLSYLEGSNKSFVVPVYQRNYNWKKEQCKRLFDDLED
                     IIDSGFRTHFLGSVVSIYSMGKEYLIIDGQQRVTTVSILLIAMCQIIKEFGESKGIIT
                     TEEQIKECYLINKHSRDKDGKIKLKPIAEDRKAYYELFEEEMNTDRNSNIVSNYLYFY
                     NRIKEDNISIDDLFDAIQKLTIVEIELKNGEDDPQLIFESLNSTGLDLSEADRVRNFV
                     LMGRSSKLQEEFYNNYWYKIEKNTSSNVSSFIRDYLTIKERSIPNKNKVYFSFKRYVS
                     DNGIDIEILLKDLLKFSNYYREISYSCTDDNDVNKVLKRINKLEIFVSYPFILELFDD
                     YNEGIINKKVLVESLNLVECFILRRIVCDVPPNALNKVFMNLGREIKKFSDYKENYSN
                     ILRYIFINKKSSQRFPT"
     gene            complement(1610..4945)
                     /locus_tag="KR231_003265"
     CDS             complement(1610..4945)
                     /locus_tag="KR231_003265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HBH0005603.1"
                     /translation="MGNFDFLQKKKNFNSFNTACLEAEKSILVSPSTCATITRRALEL
                     AVKWLYANDSDLVLPYQDNLSTLIHNNSFIELIDYDMLPLLKYIVKLGNLSVHTSANI
                     ERGEAILSLNNLHQFVSWIDYCYSDEYTAEDFNEDLLLHGEEKRTRPDELKNLYERLS
                     SKDKKLEEVIKENEELRKSLTEKRKVNTVNYDFKIDEVSEFETRKRYINIELKLAGWE
                     FGKDIWEEIEVQGMPNESGVGYVDYVLYGENGKPLAVVEAKRTSKDPKIGQQQAKLYA
                     DCLEKRYSQRPVIFLTNGFDMYIWDDYSDRKVYGFYKKSELQLMIDRRKSKKSLSSVT
                     INDEISNRYYQKEAIRAVCEALENKQRKTLLVCATGTGKTRIAISIVDVLSRHNWIKN
                     ILFLADRKALVKQAKKSFTKLLPNLALCNLLDSKDSPEDARMIFSTYPTMMNAIDDTK
                     SKDGKRLFTPGHFDLIIIDESHRSIYKKYKSIFDYFDSYLMGLTATPKDEIDKNTYSV
                     FDMENGVPTYAYEYNKAVEDGYLVDYTSIEFKTKIMEDGIKYDELSDEEKEEYENTFN
                     DDESIGDEIGNNAVNEWLFNSDTIDLVLNKLMTEGLKIEGEEKIGKTIIFAKNTKHAR
                     AIVERFNKLYPKYGGNFVKAVDYSINYVDSIIDDFSDKNKLPQIAVSVDMLDTGIDIP
                     EILNLVFFKKVRSKTKFWQMIGRGTRLCPDLLGVDMDKERFLIFDFCNNFEFFKFNPK
                     GFEGNKTETLTEKLFNIKVSMVKELQDIKYIEGEYAELRKELLEELITSVKALNEDSY
                     IVRMNLSYVHKYKNENVWSNIGAVAQNEIREYISPLITSYSDDELAKRFDVVMYNIQL
                     AYLQNNNASKGIRHVMATAEKLSKLGTIPQIQQQKYTIEKAMTEDFWEDSDIFEVEEV
                     RISLRELIKYLEKSSQKIYYTSFEDMIVAEDRNDSVYNANNLKNYKKKVEYYLNSHKD
                     ELAIFKLRNNKKITKQDVETLEEILLKQLGNCDDYKKEFGDTPVSQLVRRLVGLDREA
                     ANEAFSEFLNNKSFNTKQIHFVKLIVDYVVKNGFIEDNKVLMEDPFRTVGSIIDLFEN
                     HIEERNKLIKTINKIKENASEIG"
     gene            complement(4995..5423)
                     /locus_tag="KR231_003266"
     CDS             complement(4995..5423)
                     /locus_tag="KR231_003266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0005604.1"
                     /translation="MVIRNKLSWNSIEEVNRDFGSCLYDLQNFKILYDKEEMPELWAR
                     YIKEGFKSYMVSFLELTKAMLYYKSIDLNIKSKNFYDYLLACEYHNLLPKNSSIVIET
                     LRKLRNDDSHGYDIPQFEDMYELFTENEEVFVSIRNSCKK"
     gene            complement(5413..5793)
                     /locus_tag="KR231_003267"
     CDS             complement(5413..5793)
                     /locus_tag="KR231_003267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase domain-containing
                     protein"
                     /protein_id="HBH0005605.1"
                     /translation="MRNIPNEIKNSIINVFPKENTLAIIIFGSYGTDKHTSESDIDIA
                     WIPIKKVPITELATKTEALRNILDIDVDLKIVTDNYTIALKKAILEGEVIYKSKDFKD
                     YINKFYFENSDVIDILDWRDMYGN"
     gene            complement(5826..6134)
                     /locus_tag="KR231_003268"
     CDS             complement(5826..6134)
                     /locus_tag="KR231_003268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0005606.1"
                     /translation="MNQIELDLYHNMVNIYKEADLQCNYKPTRFLQLINNKGALLAAK
                     ELINKEGATEGFTRLWECKRLDLSLEVLVLKEKYKELFTDEEREICINRLKDYGYKFN
                     "
     gene            complement(6179..7339)
                     /locus_tag="KR231_003269"
     CDS             complement(6179..7339)
                     /locus_tag="KR231_003269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HBH0005607.1"
                     /translation="MEYRLNEVFEFIRNGASIKQFDTKFGYPITRIETIANSYIDTNK
                     MGYADIKELGKLEDYLLKNGDILMSHINSEKHLGKSAIYEDINKKIIHGMNLLCLRPD
                     KEVCYPKYLNYFFNSNEFRRQLPRIIKKSVNQASFSVNDLKNLKVDLPEMEAQKDISK
                     VLDKAQELIDKRKEQIEALDELVKSRFIEMFGNFKEQKFVLLKDCTNFIDYRGKTPIL
                     SENGIRIINAKSVGNGVFKYINEYISENTYNSWMKRGFPVAGDVLFVTEGHTFGNVCR
                     IPKDLKKFAMGQRIITIQGDKKILNNAFLAQYMQTKAFRVEIDKYKTGSSAQGIRSKE
                     LQKILIPVPSIELQNKFEEFVNQVDKLKVGIKTSLKELEDNFNSLMQKAFKG"
     gene            complement(7343..8806)
                     /locus_tag="KR231_003270"
     CDS             complement(7343..8806)
                     /locus_tag="KR231_003270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAM-dependent DNA methyltransferase"
                     /protein_id="HBH0005608.1"
                     /translation="MITGELRSKVDKIWETFWTGGLTNPLEVIEQFTYLLFIKGLDEV
                     ETKNEAEATLLGVSFEKIFDDEHQHLRWSKFSNEGNSEKMYEIVQNEVFPFIKKLHGN
                     KESAYAKYMGDAIFKIPTPLMLSKIVDGISNLELSKDRDTKGDLYEYLLSKVATAGTN
                     GQFRTPRHIIDMIVRLIKPTPEDIIVDPAAGSAGFLVSSQQYLRDNHSSLFLVQGLKE
                     HFNNGMFYGFDMDRTMLRIGAMNMMLHGVDNPNIEYKDSLSEVNTDKDKFTLVLANPP
                     FKGSLDYEAVSADLLKVTKTKKTELLFLALFLRVLKIGGRCACIVPDGVLFGSTGGHK
                     SIRKEIVDNHKLEAIISMPSGVFKPYAGVSTAIMIFTKTGTGGTDKVWFYDMKADGYS
                     LDDKRNEIKDSDIEDIIKRFDNLDGEVDRKRTEQSFFVDVEEIRENGYDLSINKYKEV
                     VYEEVVYDAPSVIIGRVRELEKEIVDGLEELERMLEV"
     gene            complement(9315..10184)
                     /gene="gatY"
                     /locus_tag="KR231_003271"
     CDS             complement(9315..10184)
                     /gene="gatY"
                     /locus_tag="KR231_003271"
                     /EC_number="4.1.2.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-bisphosphate aldolase subunit GatY"
                     /protein_id="HBH0005609.1"
                     /translation="MALVTTKQILLDAQEGHYAVGAFNVENMEMVMAVIEAAEELKSP
                     VILQTTPSTIKYAGLDYYLANVKVASEKASVPVAMHLDHGSSFGLAMQALRVGYTSIM
                     IDGSHESYEDNISISKSVVDACMPSDIPVEAELGKVGGKEDDLDGGDGGAYTDPLEAK
                     EFVERTGVSSLAVAIGTAHGLYKGEPKLDLDRLSEIREVVSVPLVLHGGSGIPDEVIK
                     ESIKRGICKVNYATELRIAYSNGVKDVLNSDPEVIDPKKYGKKGLESVKDFVKSRMEV
                     CGCVGKAIEIVKC"
     gene            complement(10204..12120)
                     /locus_tag="KR231_003272"
     CDS             complement(10204..12120)
                     /locus_tag="KR231_003272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIABC"
                     /protein_id="HBH0005610.1"
                     /translation="MGKKMILGVTGCPTGIAHTFMAEEALKNSARELGCDIKVETNGA
                     IGVENKLTAKDIEMADAIIVACDKNVDMDRFNGKPVIEVPVKEGIHKANELIQRCIDG
                     KVAIRKGNLSSSKIAEEGNLSFGQKLYKDLMNGVSHMLPLVVAGGVLTAISFLWGIYS
                     FDPNSEQYNQIAATLKSVGGYSMNLMVPVLAAFIAQSISGRAGMLAGLVGGMISFDTG
                     SGFLGGIISGFLAGYLVKLFVHLLRKLPRQLEGLKSIFIIPIVSVGLVGVAMLLLGGP
                     CSALNNAMMNFLSGLQNSSPIILGIVIGCMSAFDMGGPVNKAAYVTGTMLLGQGNYLF
                     MAGVSAACITPPLVIAIASTLFKNRFTEEDRAAGLINYILGSTHITEGAIPFAAKNPL
                     KVLPVLMIASSISSILTYIMKIEVPAPHGGFLVLGLVNKPLLWVGCIFVGSLVGAVLY
                     MMVTPKVVNEKNTIENTNVTKDEHKNESAESENVSNNISLYSEETVILDVKGKNKTDV
                     IDEMIGILDKSSVLLDKKKFKEEILKREEISSTGFGMGIAIPHAKTDAVKVPRVAVGL
                     SKEGFDFESEDGSLAHIIFMIAATDNGDNLHLKTLSQLSSKLMNEEFLNELLNSKTSR
                     EIVSKLNNEEIKSV"
     gene            complement(12123..13043)
                     /locus_tag="KR231_003273"
     CDS             complement(12123..13043)
                     /locus_tag="KR231_003273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906218.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-phosphofructokinase family hexose kinase"
                     /protein_id="HBH0005611.1"
                     /translation="MIYTLTTNPAIDMNISTNGIKRKLVNRTSNAVYSPNGKGLNVTF
                     VLGHYGIESKILGFFGGFSGKYIVEESEKRGFDVLPTWVEDTTRINIFLNDGSDEFKF
                     VNSGSYVNEKQKLDMLDKIQSLEDISYLSISGSLPPGIDDNYYEDIFKICENKSIKTI
                     LDISSPKLKELLQYNPYLIKPNDEEIKDIFGIIVRDEEDIKDVLKLLHLKGAQNILLT
                     LGEKGSYFYNGKSIYYASAQPVTVVSSACAGDSALAAFLSIWLENPEHIEEALKRSAA
                     TGASVAESNGIGNLENVEDYIKNIRVRKVV"
     gene            complement(13145..13897)
                     /locus_tag="KR231_003274"
     CDS             complement(13145..13897)
                     /locus_tag="KR231_003274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HBH0005612.1"
                     /translation="MIIELNKSNSENLTKTELEIIKFINENESILPELSIVEIAHETY
                     SSPATVSRAIRKCGLNGFNELRYRLTVKDENDDIQNMGDIINKSFIEAQRVIEQISLT
                     TLINIIKTVNKSSKIYILARGLTEYVAKEFSLKLQLLDFNVVFINDPNIMKIKSKSIK
                     KDELIIIFSLNGNTIELVESAQNANLVGAKVITCCCSESAKLIKYSDLYIVGYKHEHI
                     SISEYEVSSRLPLYIISRIIIDYMVRYNNSEN"
BASE COUNT         4388 a         2674 c         1374 g         5668 t
ORIGIN      
        1 tcagtaggaa atctttgaga tgatttctta tttataaaaa tatatcttaa tatattagaa
       61 tagttttctt tataatcact aaatttttta atttcccttc ctaagttcat aaatacttta
      121 ttcagtgcat taggaggtac atcacatact attcttctta atataaaaca ttctactaaa
      181 ttaagggatt ctacaagtac ttttttattt attatacctt cattataatc atcaaataat
      241 tctaatataa acggatatga tacaaatatt tcaagtttgt ttatcctttt caaaactttg
      301 tttacatcat tatcatcagt acatgaataa gatatctctc tataatagtt agaaaattta
      361 agtaaatctt ttaataaaat ttctatatct ataccattat ctgatacata ccttttaaaa
      421 ctaaaatata ctttattttt attcggtata cttctctcct ttatagtcaa atagtctctt
      481 ataaaactac ttacgttgct acttgtattt ttttcaattt tataccaata attattataa
      541 aattcctctt gtaacttaga gcttctaccc attaacacaa agtttcttac tctatcagct
      601 tcacttaaat ctaagccagt tgaatttaga ctttcaaaga ttaattgagg gtcatcttca
      661 ccatttttta actctatttc tactatagtt aatttctgta tagcatcaaa caaatcatct
      721 attgatatat tatcttcttt tattctatta taaaaatata aataatttga aactatatta
      781 gaatttctat ctgtattcat ttcttcttca aatagttcat agtacgcttt tctatcttct
      841 gctattggtt ttaactttat ttttccatct ttatctcttg agtgcttgtt tataagataa
      901 cactccttaa tctgttcttc tgttgtaata attccttttg attccccaaa ctcttttatt
      961 atttgacaca tggcaatcaa taatattgac acagtagtca ctctttgttg tccatctatt
     1021 attaaatatt cttttcccat actatatata gatacaactg accctaagaa atgagttcta
     1081 aatccagaat ctattatatc ctctaaatca tcaaacaatc ttttacattg ttctttcttc
     1141 cagttataat ttctttgata tacaggtact acaaaacttt tgtttgaccc ctctaaataa
     1201 ctaagaaatt caatttctcc tgctttcata ttaactcccc ctataagtta aataaattcc
     1261 attcataact ccatgtatct atatattata tcaaaatttt gactcataaa tgtatatgaa
     1321 agccttatta tatacctttt tatacctgtt tttattttat taaagtaaat acatgattat
     1381 tctataaaat atacaaatac ttaattttaa aaattattat ttaatcttct tcatgagtaa
     1441 ttcatagtta tttatcaatt aaaaagagat attgcataat tattcaatac ctctctttgt
     1501 atatttacat tatccatatc tagttatcta tttcaaccca atattagact acctactaat
     1561 aaatttattc tctacatcat taacaataat tttgcactaa ataacatcat tagcctatct
     1621 ctgatgcatt ttctttaatt ttatttatag ttttaatcaa tttatttctc tcttcaatat
     1681 gattttcaaa taaatcaatt atacttccaa cagttctaaa tgggtcttcc atcaacactt
     1741 tgttatcctc tataaatcca ttcttgacta cataatcgac tataagttta acaaaatgta
     1801 tttgcttagt attaaagctc ttattattta aaaactctga aaaagcttca tttgcagctt
     1861 ctctatccaa tcccactagt cttctcacta attggcttac tggagtatct ccaaactcct
     1921 tcttataatc atcacaatta cctaactgtt ttaagagtat ttcctccaac gtttcaacat
     1981 cttgctttgt tatcttttta ttatttctta atttaaatat tgctaattca tctttatggc
     2041 tatttaaata atactctacc ttctttttat aattcttaag attgtttgca ttatatacag
     2101 aatcatttct atcttctgct acaatcatat cttcaaaact tgtataatat atcttttgac
     2161 tagacttttc aagatactta ataagctctc ttaatgatat acgtacttct tctacctcaa
     2221 atatatctga atcttcccaa aaatcctctg tcattgcttt ttcaatagta tatttttgtt
     2281 gctgaatctg tggtatagtc ccaagttttg aaagtttttc tgctgtagcc attacatgcc
     2341 ttataccttt acttgcatta ttattttgta agtatgcaag ttgtatatta tacataacta
     2401 catcaaatct tttagccaat tcatcatcac tatatgaagt tatgagtggt gatatatatt
     2461 ctcttatctc attttgtgct actgctccaa tattgctcca aacattttca tttttatact
     2521 tatgtacata acttaaattc atcctaacta tataactatc ctcatttaaa gcttttacag
     2581 aagttataag ttcttctaac aattcttttc taagttctgc atactcacct tctatatatt
     2641 taatatcttg aagttcttta accatactta cctttatatt aaataatttt tcagtaagtg
     2701 tttctgtttt atttccctca aatcctttag gattaaattt aaaaaattca aaattattac
     2761 aaaaatcaaa tattaagaat ctttccttat ccatatcaac acctaataaa tctggacata
     2821 atctagttcc tctacctatc atttgccaaa acttagtctt acttctcact ttcttgaaaa
     2881 aaacaagatt tagtatttca ggtatgtcaa ttcctgtatc aagcatatct actgaaactg
     2941 ctatttgagg taatttattc ttatcagaaa aatcatctat tatagaatct acataattta
     3001 tactatagtc aactgctttt acaaagttcc caccatactt tggatacagt ttattaaatc
     3061 tttcaactat tgccctagca tgctttgtat tctttgcaaa aattatagtc ttaccaatct
     3121 tttcttctcc ttctattttc aacccctctg tcattagctt atttaaaact aaatctattg
     3181 tgtcagaatt aaatagccac tcatttactg cattattccc tatttcgtct ccaatactct
     3241 catcatcatt aaatgtattt tcatattctt ccttctcttc atcagaaagc tcatcatact
     3301 taattccatc ttccataatc ttagtcttaa actcaatact agtataatct actaaatatc
     3361 catcctcgac tgccttatta tactcataag catatgtagg tactccattt tccatgtcaa
     3421 aaactgaata agtattttta tctatctcat cctttggtgt agcagtaaga cccattaagt
     3481 aagaatcaaa ataatcaaag attgacttat actttttata aatacttcta tgcgattcat
     3541 ctattataat taaatcaaaa tgaccaggtg taaacaatct ctttccatcc ttagacttcg
     3601 tatcatcaat tgcattcatc attgttggat atgtagaaaa tatcatccta gcatcttctg
     3661 ggctgtcttt gctatccaat aaattacata acgccaagtt aggtaatagc ttagtaaaac
     3721 tttttttagc ttgctttacc aatgcttttc tatctgctag aaataatata tttttaatcc
     3781 aattatgtct tgaaagtaca tcaactatag atatagcaat tcttgttttt cctgtaccag
     3841 tagcacatac caaaagagtt ttgcgttgct tattttcaag agcctcacat acagccctaa
     3901 tagcttcttt ttgataatat ctattggata tttcatcatt tattgttaca gaacttaaag
     3961 acttcttact ctttcttcta tctatcataa gttgtaattc tgatttttta taaaatccat
     4021 aaactttcct atctgaatag tcatcccaaa tatacatatc aaaaccatta gtcaaaaata
     4081 ttaccggtct ttgactatat ctcttttcca aacaatctgc atataattta gcttgttgtt
     4141 gaccaatttt cgggtcttta ctcgttcttt tcgcctcaac tactgctaat ggcttaccat
     4201 tttcaccata aagaacataa tctacatatc ccacaccact ttcattaggc ataccttgta
     4261 cttctatttc ttcccatata tcttttccaa attcccaacc tgcaagcttt aattctatat
     4321 ttatatatct ttttcttgtc tcaaattcgc ttacttcgtc tatcttgaaa tcatagttta
     4381 cagtattaac ttttctcttt tcagttagtg actttcttaa ttcctcattt tcttttatta
     4441 cttcttcaag ctttttatct tttgaactta atctctcata aagattttta agttcgtctg
     4501 gtctcgtcct tttctcttcc ccatgaagta ataaatcttc attaaagtct tctgctgtat
     4561 attcatctga ataacaatag tctatccaac taacaaattg atgcaaattg ttaagtgaaa
     4621 gtattgcttc tcctctctct atgttcgcac tagtatgtac agataaatta cctaatttaa
     4681 ctatatattt taataaaggt aacatatcat agtctataag ttctataaaa ctattattat
     4741 gaatcaacgt actaagatta tcttgataag gcaatactaa atcactatca ttagcatata
     4801 gccattttac tgcaagctct aaagctcttc ttgttatagt tgcacaagta gatgggctaa
     4861 ctagtatact tttttctgct tctaagcaag cagtattaaa actattgaaa tttttcttct
     4921 tttgtaaaaa atcaaaatta cccaaggctt ttatccccct tttgtccctt agttaaaata
     4981 aatctctcta aaaactattt cttacagctg tttcttatac taacaaatac ttcttcattt
     5041 tctgtaaaca attcgtacat atcttcaaac tgtggtatat catatccatg agaatcatca
     5101 tttctcaatt ttctaagtgt ttctataact atagaagaat ttttaggtaa taaattgtga
     5161 tactcacaag ctaaaaggta gtcataaaag tttttagatt ttatgtttaa atcaattgat
     5221 ttataataca acattgcttt tgttaattct agaaatgata ccatatagct tttaaagcct
     5281 tcttttatgt atctagccca taactcaggc atttcttcct tatcatataa gattttgaag
     5341 ttttgcaggt catacaagca agaaccaaaa tccctattta cttcttctat tgagttccaa
     5401 gataatttgt ttctaattac catacatgtc cctccaatct aagatatcta ttacatcact
     5461 gttttcaaaa tagaatttat ttatataatc cttaaaatct ttagatttat aaataacttc
     5521 accttctaaa atagcttttt taagtgctat tgtataatta tctgtaacaa tttttaggtc
     5581 tacatcaatg tctaatatat ttcttagagc ttctgtctta gttgcaagtt ctgtaattgg
     5641 tacttttttg atgggaatcc aagctatgtc tatatcactt tctgatgtat gtttatctgt
     5701 tccataacta ccaaatatta tgattgctag agtattttct tttggaaata catttattat
     5761 tgagttttta atctcatttg gtatatttct catttaatca cctcttgttt attaggtaat
     5821 attgcttaat tgaatttata tccataatct tttaatctat ttatacatat ttctctttct
     5881 tcatcagtaa acaactcttt atacttttct tttaatacta atacttctaa tgataaatct
     5941 aatctcttac actcccatag ccttgtaaat ccttcagtag ctccttcttt attgattaat
     6001 tctttagcag ctaataaggc tcctttgtta tttatcagtt gtaaaaatct tgttggctta
     6061 tagttacatt gtaaatcagc ttctttatag atatttacca tgttatggta taaatctagc
     6121 tctatttgat tcatagattt tattccccca ttttaataat tgtattttag ttgaataact
     6181 atcctttaaa agctttttgc attaatgagt taaagttgtc ttctagttct tttagacttg
     6241 tttttattcc tactttcaat ttgtctactt gattaacaaa ctcttcaaac ttattttgaa
     6301 gttctattga tggtactggt attaatattt tttgaagttc tttgcttcta attccttgtg
     6361 cagagctacc agttttatat ttatctattt ctaccctaaa agcttttgtt tgcatatatt
     6421 gtgctaaaaa agcattattt aaaatttttt tatctccctg aattgttata atcctttgac
     6481 ccatagcaaa cttttttaaa tcctttggta tcctacatac atttccaaat gtatgacctt
     6541 ctgtaacaaa aagtacatct ccagctactg gaaaacctct tttcatccaa gaattatagg
     6601 tgttttcaga tatatattca ttaatatatt taaatacacc attccctaca gattttgcat
     6661 ttattattct aattccattc tctgaaagaa ttggagtttt accacgataa tcaataaaat
     6721 ttgtacaatc tttcaataat acaaactttt gttccttaaa atttccaaac atttcaataa
     6781 atcttgattt aactaattca tccaatgctt ctatttgctc ttttctttta tctattaact
     6841 cttgagcttt atctaaaact tttgatatat ctttttgagc ttccatttca ggtaaatcta
     6901 cttttaaatt ttttaaatca ttaactgaaa aacttgcttg attaactgat ttttttatta
     6961 tccttggtaa ctgtcttcta aattcattac tattaaaaaa ataatttaaa tactttggat
     7021 aacaaacttc tttatctggt cgtaaacata aaagattcat tccatgtata atttttttat
     7081 ttatatcttc atatattgca cttttcccta aatgtttttc actattaata tgtgacatta
     7141 gtatatctcc atttttcaat aaatagtctt ctaattttcc taactctttt atgtcagcat
     7201 atcccatttt attagtatca atataagagt ttgctatagt ttctattctt gtaattggat
     7261 atccaaattt tgtatcaaat tgtttaatac tagccccatt tctaataaat tcaaaaactt
     7321 cattcaatct atattccata ctctacacct caagcattct ttctaattcc tctaatccat
     7381 ctacgatttc cttctctaac tccctaactc tacctataat aacactagga gcatcataaa
     7441 ctacttcctc atacactacc tctttatact tattaataga taaatcatac ccattctctc
     7501 ttatctcttc cacatcaaca aaaaagcttt gctctgttct ttttctatct acttcaccat
     7561 caagattatc aaatctctta ataatatcct ctatatcact atcctttatc tcatttctct
     7621 tatcatccaa agaataacca tcagctttca tatcatagaa ccatacctta tcagttccac
     7681 ctgttcctgt tttagtaaat atcattatag ctgtagatac tcctgcataa ggcttaaaca
     7741 ctccacttgg cattgatatt atagcttcca atttatgatt atcaactatt tcttttctta
     7801 tcgatttatg tccacctgtt gaaccaaaca atactccatc tggcactata catgcgcatc
     7861 ttccaccaat ttttaaaact cttaaaaaaa gtgccaagaa taataactct gttttctttg
     7921 tcttagtcac ttttaataaa tctgctgaca ctgcttcata atctaaactt cccttaaaag
     7981 gaggatttgc taacaccaat gtaaacttat ctttatctgt attaacctcc gataaagaat
     8041 ccttatactc tatattagga ttgtcaacgc catgcaacat catattcata gcacctattc
     8101 taagcatagt tctatccata tcaaatccat agaacatacc attattaaaa tgctccttca
     8161 gcccttgcac taagaaaaga cttgaatgat tatcccttaa gtattgttgt gatgatacta
     8221 aaaaacctgc cgaacctgct gccgggtcta ctataatatc ttctggtgtt ggtttaataa
     8281 gtcttactat catatctatt atgtgtcttg gagtcctaaa ttgaccatta gtacctgctg
     8341 tagccacttt ggataataaa tactcataca aatctccctt tgtatctcta tccttactta
     8401 attctaaatt actaatacca tcaactattt tagataacat aagaggcgta ggaattttaa
     8461 atattgcatc tcccatgtac tttgcataag ctgattcttt atttccatgt aattttttta
     8521 tgaaagggaa cacttcattt tgtactattt catacatttt ttctgaattt ccttcattag
     8581 aaaacttact ccaccttaaa tgttgatgtt catcatcaaa tatcttttca aaagaaacac
     8641 ccaaaagagt tgcttctgct tcattttttg tttctacttc atccaatcct ttaataaata
     8701 aaagatatgt aaattgttct ataacttcta atggattagt taatccacca gtccaaaaag
     8761 tctcccaaat cttgtccact ttactcctta attctcctgt aatcatatat gactttccct
     8821 ccagtgttca taaaataatt taaatatata ttttagtcgt acgccttaat agttagtgtc
     8881 ttatgttaaa tccaagtttt tactacacaa ttattaaatt atttttccta tttacatatt
     8941 ttagctaaaa aactaatgca atactcttat tttatgatta ttatatatac catacaaaat
     9001 tattttatca tatatccatc atagaagtca tctacctgga taactcttac catattataa
     9061 ctttttaata ttaatttaaa cttagaaaga aattttttat ttaattatat catcttcctt
     9121 atttcaaatt tctcaattac aatcttaatc aaaaaataaa ataagatgct gtctcaaaat
     9181 agatataatc ttctttttta ttgtcggaat gatgaaaata tatttaattt catacaaaaa
     9241 agagtgcctc atgaactaaa agttcatttt gagacacccc ttaatttaat cttacttatt
     9301 ctttcccttt attattaaca cttcactatc tctattgctt ttcctacaca tccacaaact
     9361 tccatcctac tcttaacaaa atctttaact gactctaaac cttttttacc atatttttta
     9421 gggtcaatta cctctgggtc agaattaagc acatccttaa ccccattgct ataagcaatc
     9481 cttaattcag ttgcataatt aaccttgcaa atccctcttt ttatagactc cttaataacc
     9541 tcatctggta ttccagaccc accatgtaat actaatggaa ctgatacaac ctctctaatt
     9601 tcagataatc tatctaaatc aagttttggc tctcccttat atagcccatg tgccgtacct
     9661 attgctactg ctaaagatga tacccctgtt ctctctacaa actcttttgc ttctaatggg
     9721 tctgtatatg ctccaccatc accaccatct aaatcgtctt ccttacctcc aactttacct
     9781 aattcagctt caacaggtat atctgaaggc atacatgcat ctacaacaga tttagatatt
     9841 gaaatattat cttcataact ttcatgagaa ccatcaatca taatagaagt atatccaact
     9901 ctaagtgcct gcatagctag tccaaagctt gaaccatggt ctaagtgcat tgctactgga
     9961 acacttgcct tctctgatgc tacctttaca ttcgctaaat aataatctag tcctgcatac
    10021 tttattgttg aaggtgttgt ttgcaatatt actggtgatt taagttcttc agcagcctct
    10081 attactgcca taaccatctc catattttca acattaaatg cacctactgc ataatgccct
    10141 tcttgtgcat ctaataatat ttgtttagtt gtcactaatg ccataatttc tcctcctata
    10201 tgtttatact gatttaattt cttcgttatt taattttgat actatttctc tacttgtttt
    10261 gctatttaat aactcattta aaaattcttc attcattaat tttgaagata gttgagataa
    10321 tgtttttaag tgtaaattat caccattatc tgtagctgct atcataaata taatatgtgc
    10381 caagcttcca tcttctgatt caaagtcaaa cccttctttt gatagaccta ctgctacacg
    10441 tggtaccttt actgcatctg tttttgcatg tggtatcgct atccccatac caaaacctgt
    10501 agatgatatt tcttctcttt taaggatttc ttctttaaac ttctttttat ctaaaagaac
    10561 actagattta tcaagtattc caatcatttc atcaattaca tctgttttat tttttccctt
    10621 aacatctaaa attactgttt cttcgctata taaagagata ttattagata cgttttccga
    10681 ttctgcactt tcatttttat gttcatcttt tgttacattt gtattttcta tagtattttt
    10741 ctcatttact actttaggtg taaccatcat ataaagtaca gcacctacta atgaacctac
    10801 aaatatacac cctacccata aaagtggctt attgactaat cctagaacca aaaaccctcc
    10861 atgtggagct ggtacttcta ttttcattat ataagttaaa attgatgata ttgatgatgc
    10921 aatcataagt actggcaaca cttttaatgg attttttgct gcaaaaggta ttgccccctc
    10981 tgttatatga gtactaccta gtatataatt gattaatcct gctgctctat cttcttctgt
    11041 aaatctattt ttaaataaag tagatgctat tgctattacc aatggtggtg ttatacaagc
    11101 tgcagataca cctgccataa ataaataatt tccctgtcct agaagcatag ttccagttac
    11161 atatgctgct ttatttactg gacctcccat atcaaatgct gacatacatc ctattactat
    11221 tcccaaaatt atagggcttg aattttgtaa ccccgataga aagttcatca tagcattgtt
    11281 aagtgctgaa catggcccac caagtaacaa cattgctaca cccacaagac ctacgctgac
    11341 aataggaatt ataaaaatcg atttaagacc ttctaattgt cgtggtaatt ttcttaacaa
    11401 atgtacaaat agtttaacta agtaacctgc taaaaatcct gatatgattc cacctaaaaa
    11461 ccccgaacct gtatcaaatg atatcattcc tccaacaagt cctgccaaca taccagctct
    11521 tcccgatata gattgagcta taaatgctgc caatacagga accatcaagt tcatagaata
    11581 tccaccaaca gattttaatg tagctgctat ttgattatat tgttctgaat ttgggtcaaa
    11641 tgaataaatc ccccataaaa atgatatagc agtaagtact ccacctgcta ctactaaagg
    11701 taacatgtga gatacaccat tcattaagtc tttatacaac ttttgaccaa acgataaatt
    11761 tccttcttct gcaattttac tgcttgataa gtttcctttt ctaatagcta cttttccatc
    11821 aatacatctt tgtataagtt cattagcttt atgtatacct tctttgacag gtacttctat
    11881 tactggcttt ccattgaatc tgtccatatc aacattttta tcacaagcaa ctattattgc
    11941 atctgccatt tcgatatctt ttgctgttaa cttattttct acacctatag ctccattcgt
    12001 ttcaactttt atgtcacacc ctaattccct ggctgaattt tttaatgctt cttctgccat
    12061 aaaagtatga gctattccag ttggacaacc tgttacccct agaatcattt tctttcccat
    12121 ttttatacca cctttctgac tcttatattt tttatataat cttccacatt ctccaaatta
    12181 cctataccat tactttcagc cacacttgct cctgttgctg ctgacctttt taatgcttct
    12241 tcaatatgtt ctggattttc caaccatata cttaaaaaag cagctaatgc agaatcacca
    12301 gcacatgcag agctgactac tgtaactggt tgagcactag cataataaat tgattttcca
    12361 ttataaaaat aagaaccttt ttctcctaaa gttagcaata tattttgagc accttttaaa
    12421 tgtagtaatt taagtacatc cttaatatct tcttcatctc ttacaataat tccaaatata
    12481 tctttgattt cttcatcatt tggttttatc aaatatggat tatactgtag taactccttt
    12541 aattttggtg aacttatatc gagtattgtc tttatacttt tattttcaca aattttaaat
    12601 atatcctcat agtaattatc atcaatacca ggaggtagac ttccacttat tgataagtaa
    12661 cttatatctt ctaatgactg tatcttatct agcatatcta gtttttgttt ttcgtttaca
    12721 tatgacccag agtttacaaa tttaaattca tcacttccat catttaaaaa tatatttata
    12781 cgagttgtat cttctaccca agtaggcaat acgtcaaatc ctctcttttc gctttcttca
    12841 actatatatt ttcctgaaaa tcctccaaaa aatcctaata tcttagattc tataccataa
    12901 tgacctagta caaaagttac atttaatccc tttccattag gagaatatac agcatttgat
    12961 gtacgattta ctaattttct ctttatccca ttagtagata tattcatatc tattgcagga
    13021 tttgtagtta atgtatatat cattgtcttc ccccttgctt gtgctgtgta tgttttcatt
    13081 ataataaaaa agtctatgaa aatcttttca caaatagaaa atcgattttc atagactttt
    13141 caatttaatt ttcagaatta ttatatctga ccatataatc tataattatc ctagatataa
    13201 tatacaaggg caatctggaa gatacttcat attcagaaat tgatatatgt tcatgtttgt
    13261 atcctacaat atataaatcc gaatacttta taagttttgc actttcacta caacagcaag
    13321 ttataacctt agctccaact aaattggcat tctgtgctga ttctacaagc tctattgtat
    13381 ttccattcaa tgaaaatata attataagtt cgtctttttt tattgattta gattttattt
    13441 tcattatgtt ggggtcattt ataaaaacaa cattaaaatc aagtaattgc aatttaagac
    13501 taaactcttt tgctacatat tcagtaagcc ctcttgctaa aatatatatc ttactagatt
    13561 tatttacagt ttttattata ttgattagtg tagttaaaga tatttgttct ataactctct
    13621 gtgcttctat aaaggattta tttattatat cccccatatt ttgtatatca tcattttcat
    13681 cttttactgt taatctatac ctaagttcat tgaatccatt taaaccacat tttctaattg
    13741 ctcttgaaac ggttgctgga gatgaatatg tttcatgagc aatctctact atagataatt
    13801 ctggtaatat tgattcattt tcatttataa atttaattat ttcaagttcc gtcttggtta
    13861 gattttcaga attacttttg tttagctcaa ttatcatatg ttatctcccc ttatataagt
    13921 tttatttgtc taaatttatc gagtaatata atatattacc tcttaactac ttatttttat
    13981 atacaattaa gatttagtca atgtctatat atgtaaattt ataatataat aattttttgc
    14041 ttaaagttta ttatgttatc ttatagcatt ttaaaataaa aaagaattgt acctctacca
    14101 aaat
//
LOCUS       DAEPHU010000095        14037 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 01A10CD0081
            SAMN05941466-rid12468953.denovo.095, whole genome shotgun sequence.
ACCESSION   DAEPHU010000095 DAEPHU010000000
VERSION     DAEPHU010000095.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941466
            Sequence Read Archive: SRR6291087
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 14037)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14037)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068158.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 22:43:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,892
            CDSs (total)                      :: 3,805
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 87
            rRNAs                             :: 8, 1, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 55
            CDSs (without protein)            :: 55
            Pseudo Genes (ambiguous residues) :: 0 of 55
            Pseudo Genes (frameshifted)       :: 21 of 55
            Pseudo Genes (incomplete)         :: 28 of 55
            Pseudo Genes (internal stop)      :: 16 of 55
            Pseudo Genes (multiple problems)  :: 8 of 55
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14037
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941466-rid12468953.denovo.095"
                     /strain="01A10CD0081"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            444..1514
                     /locus_tag="KR231_003275"
     CDS             444..1514
                     /locus_tag="KR231_003275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH0005613.1"
                     /translation="MADIRLENVTKSYNKKNTVIENLNLTIEDGSFTVLVGPSGCGKS
                     TTLRMIAGLEDITSGRLKIEENDVTKTDASKRDIAMVFQNYALYPHMTVRENIEFGLK
                     NKKVEKEKREKLITEVIDVVGLREYLNVKPGNLSGGQRQRVALARAMVKNPKVFLMDE
                     PLSNLDAKLRNQMRTELIQLHQKLKSTFVYVTHDQVEAMSMADKIVIMNKGKIMQIGS
                     PKKIYQNPKNLFVAQFIGSPCMNILDIKNDIKFGFRPEKATLESINIDGKNDDVFSLF
                     GKVVTKEVLGNETIYCLSVLNREIRVKTENDIFDIGRTLRISVLEKDLYYFDKNGERI
                     EDVKVCKSMYSKIKGDIYEKAI"
     gene            1498..2367
                     /locus_tag="KR231_003276"
     CDS             1498..2367
                     /locus_tag="KR231_003276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HBH0005614.1"
                     /translation="MKKQFNKAYLYITPAIIGTLLFIVYPIIKTISLSFKSGSLLSST
                     FENVGLNNYTELLKNPEFIQTITNTAIYTFFMVTISISLAIVLAVWLNKNSIIHNLTQ
                     SIIFTPHVISLVSVAVLWLWIMEPQYGFLNWILSTLHLPTSKWLSSESSALMSLILIG
                     IWKTLGYNILIVLSGLKSIPNYIYEASKLDNANKITNFFKVTLPLLSPTIFFLMITTT
                     TASFQVFDEISIMTQGGPVGSTNMLSYYIYESGFIYYDIGQASAASMFLLAIVMIATY
                     ANFRLLSKKVHYQ"
     gene            2411..3271
                     /locus_tag="KR231_003277"
     CDS             2411..3271
                     /locus_tag="KR231_003277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HBH0005615.1"
                     /translation="MDIIQPIKKDKVDIKKIASKSIEILILLLLSAIFIFPFIWMLST
                     SFKNPQEMMQLPPTIIPNDIVLENYSTAWHSGPFFRYLLNSVFVTGSVLIVQFLVMVP
                     AAYAFSKIKFKGEKMLFGLLLVGLMIPPQVTFLPVYMMMSKFGFINTYVPLIIPFMTS
                     SFGIFLLRQNFMQISDEIIEAAKLDNASDLKIMFRIMVPMAKPAVITFILFNFIYHWN
                     NYFWPLVMTNTDAIRTLPIGVALLKSSEGITAWNVIMAGNIILILPIILVYIFANKKV
                     KEAFMYSGIK"
     gene            3302..4606
                     /locus_tag="KR231_003278"
     CDS             3302..4606
                     /locus_tag="KR231_003278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HBH0005616.1"
                     /translation="MKLKRKLATGLAITLLLGSLVGCSNSNDANASKGEKTDSNITKI
                     DFWAPLGGTNGETAQKMVDQFNSEHKDVQVNMLKQKDYYENATKLQAALTSKDQPDVT
                     LLEITQTGTFASAGALVDMSKYFDKTYQERFFSGLLTNSYYEDKFVGMPFNRSTPILY
                     INKDMATKAGLDPSGPKSWEELKDYASKMTNKSEDTYGFETPIDIWFYEAMVMQSGGE
                     ITNGKKVAFNNEAGQAPVKFWQDMMKAGIMKMPPGEDYNAWDVAKQDFVNGKVGMIFT
                     STADLAGLMQQTEGKFEISTAFLPKNQKYATPTGGANLVMLEGGTDKEKEASAEFIEW
                     MTQTDKIVQFSSSTGYLPTTEDATNSEKLQTLYKEKPQYKVATDQLQYAVALPMLNGY
                     KEATDKLMDEIKKGLTDLNANPKDVVSKGTSAMQAVIDKTNK"
     gene            4669..5931
                     /locus_tag="KR231_003279"
     CDS             4669..5931
                     /locus_tag="KR231_003279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkaline phosphatase family protein"
                     /protein_id="HBH0005617.1"
                     /translation="MTKVIVLSVDSLFEKDLEFVKNLPNFKSILENCSIVKNINCVYP
                     TLTYPCHTSMVTGVYPKKHGIYHNEKFDPNKENKDWYWYSKDIKAKTIIDVAKENNLT
                     TSSVLWPVMGANPNIDYNIAEIWAPSREDDPRETFERSSSKVIMDGIYNRHCHYIDWK
                     LEPNMDLFGVNCSVDIIKEYKPDLMLIHLATLDHTRHNYGLFNDEVDKALKMNDKWLG
                     DIIQATKDAGTYKDTNFIILGDHGHLRVDKVINPNVLLKSNGFIKVENGEVKDFDAYV
                     NSSGISAQIIVNNLDRLTELRELLEEFKEELFIENIFTKEEASNLGLEGDFEMVIEGL
                     EGISFGNDFEGSIIKDSDIKDYKFAVATHGHLPTKGNRPPFIAFGPNIKGGVVIEEGD
                     LRAHAATILKMFNLKLDGVEKEAFDFIM"
     gene            6118..8088
                     /gene="uvrB"
                     /locus_tag="KR231_003280"
     CDS             6118..8088
                     /gene="uvrB"
                     /locus_tag="KR231_003280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrB"
                     /protein_id="HBH0005618.1"
                     /translation="MDFKIKSDFKPTGDQPEAIKSIVDSINRNEKFSTLLGVTGSGKT
                     FTMANIIQQVKKPTLIMAHNKTLAAQLYSEFKEFFPDNAVEYFVSYYDYYQPEAYVAH
                     SDTYIEKDASINDEIDKLRHSATASILERRDTIIISSVSCIYGLGDPKDYKELMLSIR
                     PGMQRDRDDVIKRLIEIQYERNDINFTRGTFRVRGDILEIFPASNDEKAIRIEFFGDE
                     VDRITEIDYVTGKIVGTRNHVVIFPASHYVTTPERIEKAIVEIENELQEQIKFFKEND
                     RLLEAQRIEQRTKYDIEMLKEIGFCQGIENYSRHITGRSEGERPYTLMDFFPDDYLII
                     VDEAHVTIPQVRGMYAGDRSRKTSLIENGFRLPSALDNRPLNFQEFEGNINQMLFVSA
                     TPGPYEIQHSETIAEQIIRPTGLLDPIVEVRPINNQIDDLVGEITKTIEKNERVLITT
                     LTKKMSEDLTNYLKEIGIKVKYLHSDIVTLERTEIIRDLRLGKFDVLVGINLLREGLD
                     IPEVSLIAILDADKEGFLRSETALIQTIGRAARNENGRVIMYADRITDSMQNAIDETK
                     RRRDIQNLYNEEHNIIPKTIQKNIRDSIEATKVAEEEVVYGISDTDDKDEIRANIDKL
                     KSEMMEAAQNLQFERAAELRDKVKQLEEKLEK"
     gene            8107..10932
                     /gene="uvrA"
                     /locus_tag="KR231_003281"
     CDS             8107..10932
                     /gene="uvrA"
                     /locus_tag="KR231_003281"
                     /EC_number="3.1.25.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrA"
                     /protein_id="HBH0005619.1"
                     /translation="MEDKIIIRGAKEHNLKNIDLELPRDKFIVFTGLSGSGKSSLAFD
                     TIYAEGQRRYVESLSAYARQFLGQMEKPNVEYIEGLSPAISIDQKTTSKNPRSTVGTV
                     TEIYDYLRLLFARVGDVYCPTCGEKISQMTIQEIVDKMLDFPDRTKLQILSPIVRGQK
                     GTHKKVFDNIKKEGFVRVRVNGENYEVSDDIILNKNQKHNIEVVVDRIVIKDGIESRL
                     ADSIETAVKLSDGLVIAQIIDGEEILFSTKFACPEHGIGIEELSPRMFSFNAPFGACD
                     VCNGLGESKEVDPELVVPNKDLSIKQGAVAAWGSTGVNDDTYYSKMIKSLAEHFNVSL
                     TTPFKDLPDDFVEELLYGKDNIIVEFTYESKFGGTRNYKSYFEGVIVNLERRYRETNS
                     DYMRDKIEEYMAERPCPKCKGMRLKKEVLSVLVDGKNIMEVTNLSVNELIDFMENINL
                     TEKQRFIAHEIIKEIKGRAMFLRDVGLDYLNLSRKAGTLSGGEAQRIRLATQIGSALV
                     GVLYVLDEPSIGLHQRDNDRLITTLRHLTDLGNTLIVVEHDEDTMREADYVIDIGPGA
                     GIHGGEIVAQGTLDEIIENENSITGQYLSGKKQILLPETTREGNGSFIEIVKASENNL
                     KNIDVKFPLGKFTCITGVSGSGKSTLINDILYKGVASKVNRLKQRAGKHKEIKGIESI
                     DKVINIDQSPIGRTPRSNPATYTGVFDFIRDIFASTNEAKARGYKKGRFSFNVKGGRC
                     EACKGDGIIKIEMHFLPDVYVPCEICKGERYNRETLQVKYKDKTISDILDMNVEEAVE
                     FFENIPNIKRKLETLMDVGLSYIKLGQPSTQLSGGEAQRIKLAAELSKRPTGKTLYIL
                     DEPTTGLHMADVDKLIQVLQRLADTGNTIIVIEHNLDVIKTCDYVIDLGPEGGDKGGT
                     IVATGTPKEVSKVDGSYTGQFLKKYFS"
     gene            11191..13008
                     /gene="uvrC"
                     /locus_tag="KR231_003282"
     CDS             11191..13008
                     /gene="uvrC"
                     /locus_tag="KR231_003282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrC"
                     /protein_id="HBH0005620.1"
                     /translation="MFDIQEHLKKLPSEPGVYLMKDKYDHIIYVGKAISLKNRVRQYF
                     QSSKNHTSKVKSMVKNIYKFEYIITDSELEALILECNLIKRYRPKYNVVLRDDKTYPY
                     IKVTTNEDYPRILKVRRVLKDKAKYFGPYTNITAVNDTLELISSTYPIRSCKIDIDKA
                     IKNKTRPCLNLHINKCLGPCTGNVSKEEYGKMIEEIIMCLSGKEEKLMELLKEKMNES
                     SMNFRFEEAAVYRDKIKSLEEMIQKQKIDATVSDLNQDVVAMARAHNEACVQVFFIRN
                     GKIVGREHFILEGVMDSPRASILSSFVKQFYNEQEYIPKELIIEDEIEDSSILEEWLS
                     SKKGQKVTIRVPQKGEKKSLVEMVRKNAVEYLEKFSDMNKRKYEKSIGALEELKQILN
                     LEKLPIRIEAYDISNIQGVDSIGSMVVYTNAKKDKKEYRRYKIKTVIGPNDYDSMAEI
                     VDRRLKHGNLPDLILLDGGKGQVSAVKKVLELNDVDIPLWGMYKDDKHRTKGLICKEK
                     EIELDKTTNLYRFIASIQEEVHNYAITYHRSLRNKALTKSILDDIQGIGEKRKKSLLN
                     HFKDVDAIKKATMEELLEVDGMNKSIADNVYNFFRKEEN"
     gene            13008..13937
                     /locus_tag="KR231_003283"
     CDS             13008..13937
                     /locus_tag="KR231_003283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HPr kinase/phosphorylase"
                     /protein_id="HBH0005621.1"
                     /translation="METSNKVSIREIIKELKLKVVYMPDDVDYYVYSQDINRPGLQFA
                     GYFDYFAYERIQIVGKTEYNFFGLMDSHIREEVLDRFFSYEIPALIISRDLEIKPDVI
                     EKAKKYKRILLSTNRNTTRLINRLSNYLDNKLAPHTTIHGVLVDIYGIGVLIKGESSI
                     GKSETALELIQRGNRLVADDAVEIRKLDESMLVGQSPELIRHFLEIRGIGIIDVRSLY
                     GVGAIKNSKMIDLVVHLEAWDETKYYDRLGLDKEYEEILGVNVEKLVVPVKPGRNTAM
                     ILEVAAMNFRQRGMGYDAAQEFTKKLSKLIDTK"
BASE COUNT         5711 a         1613 c         2546 g         4167 t
ORIGIN      
        1 ggtaaattta taaaaattaa aaaattttta ttttttatgt ttaaaccttg taaatttggg
       61 acataatata attgtaaaac ttaatatagc aaaaataaat tactcaatct cccccactta
      121 aagacctcta tcccccatag aggtcttttt tactttcaaa tcaaattata taaaaaataa
      181 atagttttat atgactcttc ataaattaaa attacattgt gatagcaaac aatgaatatg
      241 aaaaatatag aaaattatag ctaacataag ctgtatatca tcttaacctc agtatattta
      301 acaaaaaatg tttataattt aacctttatt ttaataagtt taccatatat tcactttgtc
      361 ttaatatatc ctttacaaat taagagtatt attaatctat aagtaaatcg tagaattaaa
      421 ttaaatattt tgggaggata aaaatggcag atataagact agaaaatgta acaaaatctt
      481 ataataaaaa aaatacagtt atagaaaatt taaatcttac tatagaagat ggttctttta
      541 cagtattggt aggcccaagt ggatgtggta aatctactac gttaagaatg attgcaggtc
      601 ttgaagatat aacttcaggt aggttgaaga ttgaagaaaa tgatgttaca aaaacggatg
      661 ctagtaaaag ggatatagct atggtatttc aaaattatgc attatatcca catatgactg
      721 ttagagaaaa catagaattt ggtcttaaaa acaaaaaagt agaaaaagaa aaaagagaaa
      781 aacttataac agaagttatt gatgtagtag gattgagaga atatttaaat gtgaaaccag
      841 gcaacttatc tggaggtcaa agacaaagag tggcacttgc tagagctatg gttaaaaatc
      901 caaaggtatt tttaatggat gaaccattgt caaatttaga tgctaaatta agaaatcaaa
      961 tgagaacaga attaatacaa ttacatcaaa aactaaagtc tacatttgtt tatgtaactc
     1021 atgaccaggt tgaggcaatg tcaatggcag ataagatagt tataatgaac aaaggaaaga
     1081 taatgcaaat aggttctcca aagaagatat atcaaaatcc taaaaattta tttgtagctc
     1141 aatttatagg gagtccttgt atgaacatac tagatataaa aaatgatatt aaatttggat
     1201 tcagaccaga aaaagcaaca ctagagagta taaacataga tggaaaaaat gatgatgtat
     1261 ttagtctatt tggaaaagtt gtaactaaag aagtgttggg aaatgaaact atatattgtt
     1321 tatctgttct taatagagag ataagagtca aaacagaaaa tgatatattt gatattggaa
     1381 gaactttaag aataagtgta ttagaaaaag atttatatta ttttgataaa aatggagaaa
     1441 gaatagaaga tgtaaaagta tgtaaaagta tgtattctaa aattaaagga gatatttatg
     1501 aaaaagcaat ttaataaagc atatttatat ataacacctg ctattatagg aactttattg
     1561 tttatagtct atccaataat taagacgata tctctaagct tcaaatctgg tagtcttctt
     1621 agttcaacct ttgaaaatgt aggcttaaac aattatacag aacttttaaa gaatccagag
     1681 tttatacaaa ctataacaaa cactgcaatt tatacttttt ttatggtgac tatatctata
     1741 tcactagcca tagtacttgc tgtttggcta aataaaaatt ctataataca caatttaacg
     1801 caaagtataa tctttacacc acatgtaatt tcactagtat ctgtagctgt attgtggctt
     1861 tggattatgg agccacaata tggcttttta aactggatac tatcgacatt acatttacca
     1921 acatcaaagt ggctttcaag tgaaagttca gctttaatgt cactaattct aataggaata
     1981 tggaagactc ttggatataa tatcttaata gtgttatcag gtcttaaatc cataccaaac
     2041 tatatatatg aagcatctaa attagataat gcaaacaaaa taacgaattt ctttaaagtg
     2101 acattgccac tattatcacc aacaatattt tttcttatga taacaacaac aactgcatct
     2161 tttcaagtat ttgatgagat aagtataatg acacaaggtg ggccagtggg ttcaactaac
     2221 atgttatctt attatatata tgagtctgga tttatatact atgacatagg gcaagcgagt
     2281 gcagcgagta tgtttttgtt agctatagtt atgattgcta catatgctaa ctttagactc
     2341 ttatcaaaga aagttcatta tcaataaaga aaaagtagat attataaggt ttatccaaaa
     2401 ggaggagaca atggatatta tacaacctat caaaaaagac aaagttgata taaaaaaaat
     2461 agcatcaaaa tcaatagaaa tattaattct attactttta tctgcaatat ttatattccc
     2521 ttttatatgg atgctatcta catcctttaa aaatccacaa gaaatgatgc aattaccgcc
     2581 cactattata ccaaatgata tagtgttaga aaattatagt acagcatggc attcaggtcc
     2641 attttttaga tatttgctaa acagtgtatt tgtaacagga agtgttttaa ttgtacaatt
     2701 tttagttatg gttccagcag catatgcatt ttctaagatt aaatttaaag gtgaaaaaat
     2761 gctatttggg cttttgcttg taggacttat gattccacca caagtaactt ttctaccagt
     2821 ctatatgatg atgagtaagt ttggatttat aaatacttat gttccactta taattccatt
     2881 tatgacatct tcatttggga tatttctgct tagacagaat tttatgcaga tttcagatga
     2941 aattattgaa gcagctaaac tagataatgc ttctgactta aaaataatgt ttagaataat
     3001 ggttcctatg gcaaaaccag cagtaataac atttatatta tttaatttta tataccattg
     3061 gaataattat ttctggccct tagtaatgac aaatacagat gcaataagaa ctttaccaat
     3121 aggagttgcg ctccttaaat cttcagaagg aattactgca tggaatgtaa taatggcagg
     3181 aaatataatt ctaattttac caataattct tgtttatata tttgcgaata aaaaagtaaa
     3241 agaagctttt atgtattcag gaataaaata aaaaattaaa gactaaattt ggaggatgaa
     3301 aatgaagctt aaaagaaaat tagcaacagg attagcaata acattattat taggttcttt
     3361 agttgggtgt tcaaattcta atgatgcaaa tgcatctaaa ggagaaaaga ctgatagcaa
     3421 tattacgaag atagatttct gggctccttt aggtggaact aatggagaaa ctgctcaaaa
     3481 aatggttgac caatttaata gtgaacataa ggatgtacaa gtaaatatgt taaaacagaa
     3541 agattactat gaaaatgcaa caaaactaca ggcagcctta acatctaaag accaaccaga
     3601 tgtaacatta ttagaaataa ctcaaacagg tacattcgca tcagcaggtg ctttagtaga
     3661 tatgagtaaa tattttgata aaacatatca agaaagattc ttttctggtc ttttaacaaa
     3721 ttcatattat gaggataagt ttgttggtat gccatttaat agaagtacac caatattata
     3781 cataaataaa gatatggcaa ctaaagcagg tcttgaccct tcaggtccaa aatcatggga
     3841 agagcttaag gattatgcta gtaaaatgac aaataaatca gaagatactt atggttttga
     3901 aacaccaata gatatttggt tctatgaagc tatggtaatg caaagtggag gagaaataac
     3961 taatggtaaa aaagtagcat ttaataatga ggcaggacaa gcaccagtta agttctggca
     4021 agatatgatg aaagctggaa taatgaaaat gcctcctgga gaagattata atgcctggga
     4081 cgtagcaaaa caagattttg taaatggtaa agtaggtatg atatttacat caacagcaga
     4141 tttagcagga cttatgcaac aaacagaagg taagtttgaa atatcaacag cattcttacc
     4201 aaaaaatcaa aaatacgcaa ctcctacagg tggagctaat ctagttatgc ttgaaggtgg
     4261 aacagataaa gaaaaagaag caagtgcaga atttatagaa tggatgacac aaacagataa
     4321 aatcgttcag tttagttcat caacaggata cttaccaaca actgaagatg caacaaactc
     4381 agaaaagtta caaacattat ataaagaaaa acctcaatat aaggttgcaa ctgaccaatt
     4441 acaatatgct gttgcacttc caatgttaaa tggatacaag gaagcaactg ataagctaat
     4501 ggatgagatt aaaaaggggc ttactgattt aaatgcaaat ccaaaagatg tagtaagcaa
     4561 aggaacttct gcaatgcaag cagtaataga taaaacaaat aaataattat atagacttgt
     4621 aagttgatta aaagtattca ataatatata aatgaagagg taatgtaaat gacaaaggtt
     4681 atagtattat cagtagattc tttatttgaa aaagacttgg aatttgtaaa aaatctacca
     4741 aactttaaat ctatactaga aaactgctcc atagtaaaaa atataaattg tgtttatccc
     4801 actctgacat atccgtgtca tactagtatg gttacaggag tatatcctaa aaaacatggt
     4861 atatatcata atgaaaaatt tgacccaaat aaagaaaata aagactggta ctggtactca
     4921 aaggacataa aagcaaaaac tattatagat gtagcaaaag aaaataatct aactacctct
     4981 agtgtattat ggcctgtaat gggagcaaat ccaaatatag attataatat tgcagaaata
     5041 tgggctccta gtagagaaga tgacccaaga gaaacttttg aacgaagttc cagtaaggtt
     5101 ataatggacg gtatttacaa tagacattgt cattatatcg attggaaatt agaacccaac
     5161 atggatttat ttggagtaaa ctgttcagta gatataataa aggaatataa accagattta
     5221 atgctaatac atttagctac attggaccat acacgacaca attatggctt atttaatgac
     5281 gaagtagata aagcattaaa aatgaatgat aaatggttag gagatattat tcaggctaca
     5341 aaggatgcag gtacatacaa agatacaaat tttataatac ttggggacca tggtcatctt
     5401 agagttgata aagttataaa tccaaatgtc ttgcttaaat caaatggatt tataaaagtt
     5461 gaaaatggag aagttaagga ttttgatgcc tatgtaaatt cttctggaat atcagctcaa
     5521 ataatagtaa ataacttaga taggttaaca gaattaagag aactgcttga agaatttaaa
     5581 gaagaattat tcatagagaa tatttttacc aaagaggaag catctaacct tggtcttgaa
     5641 ggtgattttg aaatggtaat tgaaggtctt gaaggaattt catttggaaa tgatttcgaa
     5701 ggaagtatta taaaagattc agatataaaa gattacaagt ttgctgttgc gacacatggt
     5761 catttaccta ctaaaggtaa tagacctcca tttatagctt ttggaccaaa tattaaaggt
     5821 ggtgtggtta tagaagaagg agacctgaga gcacatgcag caactatatt aaaaatgttt
     5881 aatttaaaat tagatggagt tgaaaaagaa gcatttgatt ttattatgta agttgaataa
     5941 agtatttatt ttccatgaat tatagacttc tattgcaaag atagaagtct ttttttatgt
     6001 tttagattta agtaaaattt aaatgggtaa aatatttaaa ataacttaaa caattttata
     6061 aaggtatgat ataataatac atgtcaggaa ctaatgttcg aaaaaaggag tgatactatg
     6121 gattttaaaa taaaatcaga cttcaaacct acaggtgacc aaccagaagc tattaaatca
     6181 atagtggatt ctataaatag aaatgagaaa ttttcgacat tattaggtgt aacgggttca
     6241 ggaaaaacat tcacaatggc aaatatcatt caacaagtta agaaacctac cctaataatg
     6301 gctcataata aaactctagc agcacaactt tacagtgagt ttaaagaatt tttcccagac
     6361 aatgcagttg aatactttgt aagttactat gattattatc aaccagaagc atatgtagct
     6421 cacagtgaca cttatataga aaaagatgca agcataaatg atgaaataga taaacttcga
     6481 cattctgcta cagcatctat tttagagaga agagatacta taataatatc atctgtatct
     6541 tgtatatatg gacttggtga cccaaaagac tataaagaac ttatgttatc tataagacca
     6601 ggtatgcaaa gagacagaga tgatgtaata aaaaggttaa tagagataca atacgaaaga
     6661 aatgacataa actttacacg aggtaccttt agagttagag gagatatact agaaatattc
     6721 ccagctagta atgatgaaaa agcaataaga atagaatttt ttggtgatga ggtagataga
     6781 ataacagaaa ttgattatgt aacagggaag attgttggta ctagaaatca tgttgttata
     6841 ttcccagcat ctcactatgt aacaacgcca gaaagaattg aaaaggcaat tgtagaaata
     6901 gaaaacgagc ttcaagaaca aattaaattt ttcaaggaaa atgataggct attagaagca
     6961 caaagaattg aacaaagaac taagtatgat atagaaatgt taaaggaaat aggattttgt
     7021 caggggatag agaactattc tagacatatt acaggaaggt cagaaggaga aagaccatat
     7081 actttaatgg atttcttccc agatgattat ttgataattg tagatgaggc acatgtcact
     7141 ataccacaag taagaggtat gtatgcagga gacaggtcta gaaaaacatc acttatagag
     7201 aatggtttta gattaccttc tgcacttgac aatagaccat taaattttca agaatttgaa
     7261 ggaaatataa atcaaatgtt gtttgtaagt gctacaccag ggccttatga aattcaacac
     7321 tcagagacaa tagcagaaca gataataaga ccaactggcc ttttagaccc aattgtagaa
     7381 gtaagaccta taaataatca aatagatgat ttggtaggag aaataactaa aactatagaa
     7441 aaaaatgaaa gagtgcttat aaccacttta actaaaaaaa tgagtgagga cttgactaac
     7501 tatcttaaag aaatagggat aaaagttaaa tatttacact cagatatagt tacattagaa
     7561 agaacagaaa taataagaga tttaagatta gggaagtttg atgtccttgt aggaataaac
     7621 ttacttagag aaggattgga tataccagaa gtttcactta tagcaatttt agatgcagac
     7681 aaagaaggtt tcttacgttc cgaaacagct ttaatacaga ctattggacg tgcagctaga
     7741 aatgaaaatg gaagagtaat tatgtatgca gacaggataa ctgactcaat gcaaaatgct
     7801 attgatgaaa caaagagaag aagagatata caaaatttat ataatgaaga gcacaatatc
     7861 attcctaaaa ctatacagaa aaatataaga gatagtatag aagctactaa ggttgcagag
     7921 gaagaagttg tatatggaat atctgataca gatgataaag acgaaataag agctaatata
     7981 gataaattaa aatcagagat gatggaagct gctcaaaact tacaatttga aagagcagca
     8041 gaacttagag ataaagtgaa acaattagaa gaaaaattgg aaaaatagaa aggtaaaaac
     8101 aacattatgg aagataaaat tataataaga ggagcaaaag aacataattt aaaaaatata
     8161 gatttagaat taccaagaga taaatttatt gtttttacag gtttgtcagg gtctgggaag
     8221 tcttctttgg catttgatac aatatatgca gaaggacaga gaagatatgt agaaagtcta
     8281 tctgcttatg caagacaatt tttaggtcag atggaaaagc caaatgtaga atatatagag
     8341 ggtttatcac cagctatctc aattgaccag aagactacct caaaaaaccc acgttctacg
     8401 gttggaacag taacagaaat atatgattat ttgagactat tatttgcaag agtaggagat
     8461 gtgtattgcc ctacatgtgg tgaaaaaata agtcagatga ctattcaaga aatagttgat
     8521 aaaatgctag attttccaga tagaacgaaa ttacaaattc tttcaccaat tgttagagga
     8581 caaaaaggta cacataaaaa agtctttgat aatatcaaaa aagaaggatt tgtaagagtt
     8641 agagttaatg gtgaaaacta tgaagttagt gatgatataa tcttaaataa aaatcaaaaa
     8701 cataatatag aagttgtagt ggacagaata gtaattaaag atggaataga atcaagacta
     8761 gcagattcaa ttgaaactgc agttaagcta tctgatggtc ttgtaatagc ccaaataata
     8821 gatggagaag aaattctttt ttcaactaaa tttgcatgcc cagaacatgg aattggcata
     8881 gaagaattat ctccaagaat gttttcattt aatgctccct ttggtgcttg tgatgtttgt
     8941 aatggtcttg gggaaagtaa agaagttgac ccagaattag tagtaccaaa caaagattta
     9001 tcaataaaac aaggtgcagt ggcagcatgg ggttcaacag gtgttaatga tgacacttat
     9061 tacagtaaaa tgataaaaag tttagcagag cattttaatg tatctttgac aacaccgttt
     9121 aaagatttac cagatgattt tgtggaggaa ttactttatg gtaaagataa tataattgta
     9181 gagtttactt atgagtcaaa atttggagga actagaaatt ataaatcata ctttgaaggt
     9241 gtaatagtaa acttagagag aagatataga gaaactaatt cagattacat gagagataag
     9301 attgaagaat acatggcaga gagaccatgt ccaaagtgta aagggatgag acttaaaaag
     9361 gaagttttat ctgttttagt tgatggaaaa aatataatgg aagttacaaa cttatctgta
     9421 aatgaattga ttgactttat ggaaaatata aatcttacag aaaaacagag atttatagct
     9481 catgagatta taaaagagat aaaaggaaga gctatgttct taagagatgt aggtcttgat
     9541 tatttaaatt tatcaagaaa agctggaact ttatcaggag gagaagcgca acgtataaga
     9601 ttagctactc aaataggttc tgcattggtt ggagttttat atgtacttga tgagccaagt
     9661 atagggcttc accaaagaga taatgatagg cttataacta ctcttagaca tctaacagat
     9721 ttaggaaata ccttaatcgt tgtagagcat gatgaagaca caatgagaga agctgattat
     9781 gttatagaca ttggtccagg tgcaggtata catggtggtg aaatagttgc acagggtact
     9841 ttagatgaaa taattgaaaa tgagaactca ataacgggtc aatatttaag tggtaaaaaa
     9901 caaatattgc ttcctgagac tactagagaa ggaaatggaa gttttataga aatagttaaa
     9961 gcatcagaaa ataatctgaa aaatattgat gtaaagttcc cattaggtaa gtttacatgc
    10021 ataacaggtg tttcaggttc tggaaaaagt acattaataa acgatatact ttacaaaggt
    10081 gttgcaagta aagtgaatag acttaagcaa agagctggta agcataagga gataaaagga
    10141 attgaaagta tagataaagt tataaatata gaccaaagtc ctattggaag aacacctcgt
    10201 tcaaatcctg ctacttatac aggtgtattt gattttataa gagatatttt tgcatctact
    10261 aatgaagcta aagcaagagg ttataaaaaa ggtagattta gttttaatgt aaaaggtggt
    10321 agatgtgaag cttgtaaggg tgatggaata ataaaaatag aaatgcattt cttaccagat
    10381 gtatatgttc cttgtgaaat ttgtaaaggt gaaagataca atagagaaac attgcaagta
    10441 aaatacaaag ataaaactat atctgatata ttagatatga atgtggaaga agctgttgag
    10501 tttttcgaaa atataccaaa tataaaaaga aaattagaaa ctttaatgga tgtaggactt
    10561 tcatatatta aattaggaca gccttcaact caattatcag gaggagaagc acaacgtata
    10621 aaattagctg ctgaacttag taaaagacca acaggaaaga ctttgtatat attagatgaa
    10681 cctactactg gacttcatat ggcagatgta gacaagctaa tccaagtatt acaaagacta
    10741 gcagatacag gaaatacaat tatagtcata gaacataatt tagatgttat aaagacttgt
    10801 gattatgtaa tagacttagg accagaaggc ggagataagg gtggaactat agttgcaact
    10861 ggaacaccaa aagaagtatc taaagttgat ggttcttata caggtcaatt cttaaagaaa
    10921 tatttttctt aagttatata aattgtgaaa aattttagag cagatatacg ataaactgtt
    10981 ttgttataag taaattagtc aaatataagt tgtaaatagt aatacaaagt aaagtccata
    11041 ttactcttca tggttaaaat tgttttcaaa tcaattatag aagggaatat gggctttaac
    11101 ttgtttaaag cactggaaat tgtataactt tttaaaattc atattttagg gtataatttt
    11161 agtataaaat ttaatgtttt ggagggcgag atgtttgata tacaagagca tttaaaaaaa
    11221 ttaccttctg agcccggagt atatttaatg aaagacaaat acgaccatat aatatatgtg
    11281 ggaaaagcca tatctctaaa aaatagggta aggcagtatt ttcaatcttc aaaaaaccat
    11341 acatctaaag taaaatctat ggttaagaat atatataagt ttgagtatat tataacggat
    11401 tcagagttag aggcattaat acttgaatgt aatttaataa aaagatacag accaaagtat
    11461 aatgtagtgc ttagagatga taaaacttat ccatatataa aagtaactac gaatgaagat
    11521 tatccaagaa tcttaaaagt tagaagagtt cttaaagata aggcaaagta ttttgggccc
    11581 tataccaata taactgctgt gaatgatacc ttggagctta taagtagtac gtatccaata
    11641 agaagctgta aaatagatat agataaagca ataaagaata agacaagacc ttgtttaaat
    11701 ctacacataa ataaatgttt aggaccttgt acaggaaatg tttctaaaga agagtatgga
    11761 aaaatgatag aagagattat aatgtgttta tctggtaaag aagaaaaatt gatggaactt
    11821 ttaaaggaaa aaatgaatga gagttctatg aactttagat ttgaagaggc tgctgtatat
    11881 agggataaga taaagagcct tgaagagatg atacagaaac aaaaaataga tgctactgta
    11941 agtgacttaa accaagatgt ggttgcaatg gcaagagctc ataatgaagc ttgtgtccag
    12001 gtatttttta taagaaatgg taagattgta ggtagggaac attttatatt agaaggggta
    12061 atggatagtc caagagcttc tatattaagt tcatttgtaa aacaatttta taatgaacaa
    12121 gagtatatac ctaaagaatt aattatagaa gatgagatag aagatagttc tatattagaa
    12181 gaatggctgt catctaaaaa ggggcaaaaa gtaacaataa gagttcctca aaagggagag
    12241 aagaaaagct tagttgaaat ggttaggaaa aatgctgtag aatatcttga aaaattttct
    12301 gatatgaata aaagaaaata tgaaaaaagt attggagcat tggaagaatt aaagcaaata
    12361 ttaaatctag aaaagttgcc aataagaata gaggcttatg atatatcaaa tatacaaggt
    12421 gtagattcga ttggttctat ggtagtgtat acgaatgcta aaaaagataa gaaggaatat
    12481 aggagatata aaataaagac agttattgga cctaatgatt atgattctat ggctgaaatt
    12541 gtagatagaa gattaaaaca tggaaattta cctgacttga tattgttgga tggtggaaaa
    12601 ggacaagtta gtgcagtaaa aaaagtacta gaactcaatg atgtagatat acctctttgg
    12661 ggaatgtaca aagatgataa gcatagaact aaaggattga tatgcaaaga aaaagaaata
    12721 gaactagata aaacaactaa tttatataga tttattgcta gtatacaaga agaagttcat
    12781 aattatgcaa taacatatca tagaagtcta agaaataaag ctttgacaaa atctatctta
    12841 gatgatatac aaggaatagg tgaaaaaaga aagaaatcat tattaaatca ctttaaagat
    12901 gtagatgcta taaaaaaagc tactatggaa gaacttttag aagtagatgg aatgaataaa
    12961 agcattgcag ataatgttta taattttttt agaaaggaag aaaattaatg gaaactagca
    13021 ataaagtatc aataagagag ataataaaag agttgaagtt aaaagtagta tacatgcctg
    13081 atgatgtaga ttattatgtc tactctcaag atataaatag accaggatta cagtttgcag
    13141 gatattttga ttattttgca tatgaaagaa tacaaatagt tggaaagaca gaatataatt
    13201 tttttggatt aatggatagt catattcggg aagaagtact agatagattt ttctcatatg
    13261 aaataccagc gttaataatt tctagagact tggaaatcaa gccagatgta attgaaaagg
    13321 ctaaaaaata taaaagaata cttttgagca caaatagaaa taccactaga cttataaata
    13381 gactgtcaaa ctatttggat aataagttag caccacacac aacaattcac ggggtgctag
    13441 tagatattta tggtataggt gtactgataa aaggtgaaag tagtatagga aagtcggaaa
    13501 cagcattaga attgattcaa aggggtaata gattagttgc agatgatgct gtagaaataa
    13561 gaaaattaga tgaaagtatg cttgtgggtc agtcacctga actaataaga cattttcttg
    13621 agataagagg aataggaata atagatgtta gaagtttata tggagtaggg gcaatcaaaa
    13681 attctaaaat gatagattta gtagttcatt tagaagcttg ggatgaaact aagtattatg
    13741 atagactggg actggataaa gaatatgaag aaatacttgg tgttaatgta gagaaattag
    13801 ttgtacctgt taaacctgga agaaatactg ctatgatatt agaagtagca gcaatgaatt
    13861 ttagacaaag aggaatggga tacgatgcag ctcaagaatt tactaaaaaa ttatcaaaat
    13921 taatcgatac taagtagtac tgaataatag tgaactacac atcatttaat taaatattga
    13981 ttaggattat gtcctacacc ttataaatta aaatcaagtt gtatatatat aatgttt
//
LOCUS       DAEPHU010000096        13422 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 01A10CD0081
            SAMN05941466-rid12468953.denovo.096, whole genome shotgun sequence.
ACCESSION   DAEPHU010000096 DAEPHU010000000
VERSION     DAEPHU010000096.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941466
            Sequence Read Archive: SRR6291087
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 13422)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13422)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068158.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 22:43:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,892
            CDSs (total)                      :: 3,805
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 87
            rRNAs                             :: 8, 1, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 55
            CDSs (without protein)            :: 55
            Pseudo Genes (ambiguous residues) :: 0 of 55
            Pseudo Genes (frameshifted)       :: 21 of 55
            Pseudo Genes (incomplete)         :: 28 of 55
            Pseudo Genes (internal stop)      :: 16 of 55
            Pseudo Genes (multiple problems)  :: 8 of 55
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13422
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941466-rid12468953.denovo.096"
                     /strain="01A10CD0081"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            complement(111..821)
                     /locus_tag="KR231_003284"
     CDS             complement(111..821)
                     /locus_tag="KR231_003284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBH0005622.1"
                     /translation="MTSICICDDEKQQRNMLNKIITREMDLWGYPYQIKEYSNGESLV
                     YNLEHENYYIDIIFLDIELGKSNGVDIAKTIRKHSKDTIIIFVTGFSDYVFHGYDVGA
                     LNYILKPYKTEKICKVLKEALKKLEQWKENFITVQIGTNLCKINTKDILYFKSELRKL
                     TVVTFDKTLEYYGKLNDMETVLPSNFIRTHQRYIVNLNHVDSITQTYAKVQNEKIPIS
                     RKKYQEVVGKFTRYMLEP"
     gene            complement(1205..3316)
                     /locus_tag="KR231_003285"
     CDS             complement(1205..3316)
                     /locus_tag="KR231_003285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBH0005623.1"
                     /translation="MTINKLYSKLRAYNWKNYTTLFFCIILSVVLVTSYALIYFSPTI
                     QNILPTGGDSRKQATMIFSVAILGCAVFTTYASSLFLKFKSKEIGIFMALGTDKKKLK
                     KLLFSEILLISIVCCFLGLILSIPVSFGIWKIFQLVIIDTREMTYHFGTQGFIYGFIF
                     SVFVTLCIFILSVKFINRTNIIDILNDQRISEPIQDVKDWYGILGIIFIILGIFLGYL
                     VPSLTINKLNYKLPSIWSFTYLLSLIGIYMIMTYIVVHAKRGKHPEKYYKNIISTSMM
                     RFMGRQTVKNMCVISFLIAGALFAVFYVPNMVTGIYDTLKNNPIDYTFTYNQRDKQVS
                     KKDIEQLADKHNIKIQNYMEIPSIELIVDGVESIYHKDGTIEKVYMKKSSYDMFFNSK
                     DFSKLIGKPITIKNGEYLAVVNKGNENQDYKYTKFISSPVTEKEIPFRYAGKIIFNGS
                     FFQNRSMNAYVLNDEDYKSFTKDLSIKNYNNSILFNVDKDTYAFANDLKKEIIKRTSK
                     EMGMFSGYDEYVKKRYESTGRKYFMDEEYPSGEGHLKLDPNNNQLYLNWKYYPNFKIL
                     QSQDMIKNMAVFLMLFIYVAIICFTAVGIIAYTRGVTIAINHKQVFMDLNRLGANNDY
                     IKFCIRNQLKKVFSYPLIAGSFLIYLFNFMIMLNNDGRIVNSEVNALLINLGFIGICG
                     VYMYLIYLLTYKKFKKIIGIL"
     gene            complement(3306..4058)
                     /locus_tag="KR231_003286"
     CDS             complement(3306..4058)
                     /locus_tag="KR231_003286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH0005624.1"
                     /translation="MLKVNQLCKSYKTGSKTYPVLKNISFEINKGEFVAIMGSSGSGK
                     TTLLNCISCFIPIDNGEIILGNNNIRNLKEKELSEVRNQQLGFVFQDFMLFDGLSVFE
                     NICVPQIIKGSQVLQMENRAINLCELFGIEHIRKKYPAEISGGEKQRTAVARALMNNP
                     DLILADEPTGNLDSKSCRTVIESFLKAKQELDATILMVTHDSFAASFCDRVIVLKDGI
                     IYKEVVKSNSRHKFLDELLEVLKEMGGAQDDN"
     gene            complement(5324..5500)
                     /locus_tag="KR231_003287"
     CDS             complement(5324..5500)
                     /locus_tag="KR231_003287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0005625.1"
                     /translation="MFFTFIGVISAILLLCTIICGLWIKLNNRNNDSNSHFTFSILSI
                     AFSLLIVVAFLVRN"
     gene            complement(5604..6212)
                     /locus_tag="KR231_003288"
     CDS             complement(5604..6212)
                     /locus_tag="KR231_003288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429516.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBH0005626.1"
                     /translation="MGKLLRGKIMKADSTKEQLINATIQLLSSHRDVSSITAREIVAK
                     ANVNLAMINYYFKSKEELINISIKKFLKRHMDEYKATHDTKNLAPKQQLREILIAFFD
                     FIGEHSQFIKISVPYILIQEEIVYPFEILPLIKAHYENQNNKKTEAEYRTIAYQITSF
                     IQLLFLRSNAFFKYSGIDILNIEQRNGLIDFQLDLLLVDITK"
     gene            complement(6311..7135)
                     /locus_tag="KR231_003289"
     CDS             complement(6311..7135)
                     /locus_tag="KR231_003289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HBH0005627.1"
                     /translation="MFKIGEVSKLTQISIRMLRYYDELGILKPAEIDKYTGHRLYSVE
                     QISILQRIVLLRDSKFSVAEIANIVHNWNDEFVIKELNRKKNEIQKEINQEQQRINKI
                     DKFIEAINCDKDEIHYNVVFKKIPSYKIISLREIIPDYQSEGILWEKLSKFIKEEHIE
                     VSRQSNNNIAFYHDEEVKDNGVDIEVGMVVKKIGKNKSGFIYRETEEIDMMACTMVYG
                     PYENIAGAYESFCYWLDKNSDYQISGINRQIGHKGEHNEINPENYLTEIQIPLIKV"
     gene            complement(7313..8206)
                     /locus_tag="KR231_003290"
     CDS             complement(7313..8206)
                     /locus_tag="KR231_003290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HBH0005628.1"
                     /translation="MQLYNTPFNTNKHLIYFFTFTLVLNWIFSLTPALLGITNTILGE
                     IIFYLAYTSPAIVGLFFISTIYPQSAKQDFIYRYLSFKEIRIKWILLTILFFALTFIT
                     SLIIGNYFNVKTSDIDWIHIAVFRPSKIAYMLLASFILSILSQEAGWRGYAIDKLLVR
                     FGFIGSSIILGLVCGIWYLGSYFTPNQIPYNLAQYSLFDAFLFIPNIVLLNFIINFVY
                     INTSRSILSAGLVHMMYYFFNIQLLLHYPIKLCVIAQYVQIIFGLIFLVYMISSNKFK
                     QKVNSEIEQIKSDDFEFELDW"
     gene            complement(8463..8900)
                     /locus_tag="KR231_003291"
     CDS             complement(8463..8900)
                     /locus_tag="KR231_003291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LytTR family transcriptional regulator
                     DNA-binding domain-containing protein"
                     /protein_id="HBH0005629.1"
                     /translation="MKIHVEQGINCDDIEITIKCSALDNNIEKIISLLSTPLLDIKGK
                     KSGEIYKLNVCDILYFETVGNKTFAYYEDDVFEIDLKIYKLSKLLANTSFSRISKSMI
                     LNMDYIKSIKVISHNRMQATLKNNEKVIINRRYIKNIKEKLNI"
     gene            complement(9157..9306)
                     /locus_tag="KR231_003292"
     CDS             complement(9157..9306)
                     /locus_tag="KR231_003292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YvrJ family protein"
                     /protein_id="HBH0005630.1"
                     /translation="MDDSLQLLITNVGFPIALSMYLLVRIEGKLNTLSNSIDTLSKNI
                     LIFKK"
     gene            complement(9319..9549)
                     /locus_tag="KR231_003293"
     CDS             complement(9319..9549)
                     /locus_tag="KR231_003293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2922 domain-containing protein"
                     /protein_id="HBH0005631.1"
                     /translation="MEIKKKLVMSFKNVKDKQVSFSIENPKDDLTEENIKSVMDLIVS
                     KNIFSVGGFDLASVVEAKVVETNTTPYDLVIE"
     gene            complement(10367..10588)
                     /locus_tag="KR231_003294"
     CDS             complement(10367..10588)
                     /locus_tag="KR231_003294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1659 domain-containing protein"
                     /protein_id="HBH0005632.1"
                     /translation="MEVVSTKNLSSIKLKLDAGFDDKGKAVVKSKSFANVKAEALNED
                     VYAVAEAIASLQENPIVDILKLDSTSLSK"
     gene            11168..11425
                     /locus_tag="KR231_003295"
     CDS             11168..11425
                     /locus_tag="KR231_003295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HBH0005633.1"
                     /translation="MKIKVEDIPVQFHAMVEIIGIDKFIEVAKLYGGTNTYIPTYKGL
                     FRYARNRDIVKQFNGVNHNELAIRYNMCVSNIKRILNENNV"
     gene            11894..13132
                     /locus_tag="KR231_003296"
     CDS             11894..13132
                     /locus_tag="KR231_003296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conserved phage C-terminal domain-containing
                     protein"
                     /protein_id="HBH0005634.1"
                     /translation="MNKGFYKLNSVVLNFDIKNDVNKIRFNHYIMRKENIQRLQGTLP
                     NGQFYMTVRRAATDLQLSISTISRLVKEFLDLGIIRLVSKGVKGNRSVYSYVSIEFNG
                     SLFDDSKYMELDCVCNDEFIDNSGIEFDCDSKDNSFNGDINVETVHCINEYLSDDDVE
                     HNYNNFHNKDTIKDKAISNISTIKKYIDESFDKNKSENSNLQQESINFNFNDTCNEID
                     KRTNNSIENNQNKRPMRLSDISLLSDKGMTNKKNYFNHNHGIQKGTKSVTKKKESLNK
                     FNKKNIQQSIINMLNKKSGKNFKIDSPISIKLINERLKEGYVLEDFYKVIEVKVAKWK
                     NTIMEMYIRPETLFSYKFESYVNENISMKSQSNVHPCKEGNSNDSSNYIHSDYTTYDG
                     SVRERKKYENVRYWNPICEI"
BASE COUNT         4969 a         1608 c         1769 g         5076 t
ORIGIN      
        1 ttctagaaat taatcttcaa aaaattaaat ttgaaaaaac aaaactctaa aaactaagct
       61 ttaaaaagtt aagtttcaaa aataaaattc tagagattga acttcaaaaa ttaaggttct
      121 aacatatacc ttgtaaattt tcctacaacc tcttgatatt ttttacggct tataggaatt
      181 ttttcattct gaactttggc ataagtttga gttatactat ctacatggtt tagattgaca
      241 atataccttt gatgcgtacg tataaaatta gagggaagaa cagtttccat atcatttaat
      301 tttccgtagt attctaatgt tttatcaaag gtaactacag ttaattttct tagctcactt
      361 ttaaagtaga ggatatcttt tgtattaatt ttacaaagat tagttccaat ctgaactgta
      421 ataaagtttt ctttccattg ttctaatttt tttagtgctt cttttaatac tttacatatt
      481 ttttcagttt tataaggttt taagatgtag ttcaaagctc ctacatcata tccatgaaat
      541 acatagtcag aaaaacctgt gacaaagatg attatagtat cctttgaatg ttttcgtata
      601 gtttttgcta tgtcaacgcc attacttttt ccaagttcaa tatctaaaaa aataatatct
      661 atgtaataat tttcgtgttc tagattgtat actagacttt ctccatttga atattctttt
      721 atttggtagg ggtagcccca caaatccatt tctcttgtaa tgattttatt cagcatgttt
      781 ctttgttgtt tttcatcatc acaaatacaa atcgaagtca attttttatc tcctttcaaa
      841 ttttatattt atatagttaa gtatataata tattttgcta cctagatata taaaatgaaa
      901 taacaattat atccagatag caaaataaaa ttttttatat tagtatactt acacttaaaa
      961 ctattctatt aaacttattc tgaagtgcta atgattttct tattaaaaaa tctaacaatc
     1021 tttcttatta taaaatacaa atgcttttat tattataaaa agtaatgatt ttattacttt
     1081 aaaaatctaa taacctttct tattataaaa caccaatgat tttattactt taaaaatcta
     1141 ataacctttt ttattataaa acaccaatga ttttattact ttaaaaatct aataaccttt
     1201 tttattataa aataccaata atttttttga atttcttata agttaataga tatataaggt
     1261 acatataaac cccacaaatc cctataaaac ctaagtttat caaaagagca ttgacctcac
     1321 tattgacgat tctaccatca ttatttaaca taatcataaa attaaacaga taaattaaaa
     1381 aacttcctgc aataagaggg tatgaaaata ctttctttaa ttgatttcta atacagaact
     1441 ttatataatc attgtttgct cctaatcgat ttaaatccat aaagacctgc ttgtgattta
     1501 tagctatagt aacacccctt gtatatgcaa tgattcctac tgctgtaaaa catatgattg
     1561 ccacatatat gaataacatt aagaagactg ccatgttttt tatcatatct tggctttgta
     1621 aaattttaaa gttaggatag tatttccaat taagatacaa ctgattgttg tttgggtcta
     1681 gttttaaatg accttcacca cttggatatt cttcatccat aaaatatttt cttccagttg
     1741 attcataacg tttttttacg tattcatcat aaccactgaa catgcccatt tccttagatg
     1801 ttctttttat aatttctttc tttaagtcat tggcaaaagc ataggtatct ttatctacat
     1861 taaatagtat agaattattg taatttttta tggataaatc tttagtaaat gatttataat
     1921 cctcatcatt aaggacatag gcgttcatac ttctattttg aaaaaaagaa ccattaaata
     1981 ttatttttcc agcatatcta aaggggattt ctttttctgt gactgggctt gatataaatt
     2041 tggtatattt ataatcttga ttttcatttc ctttatttac aacagcaaga tattcaccat
     2101 tttttatagt tattggtttg ccaattagct tggaaaaatc tttagaatta aagaacatat
     2161 cataggagct ttttttcata tatacctttt cgatagttcc atctttatga tatattgatt
     2221 ctacaccatc aacaattaat tctatagaag gaatttccat atagttttga atttttatat
     2281 tgtgtttatc tgctaattgt tcaatatctt tttttgatac ctgtttatct ctttgattgt
     2341 aggtaaaagt ataatctata gggttatttt taagagtatc atagatacct gtaaccatat
     2401 taggaacata gaatacagca aataatgctc ctgcaatcaa aaatgaaata acacacatgt
     2461 tttttactgt ttgtcttccc ataaatctca tcatgctagt tgatatgatg tttttatagt
     2521 atttctctgg atgttttcct cttttagcat gtacaactat gtatgtcata atcatatata
     2581 ttccaataag agagagtaga taagtaaagc tccatataga tggtagttta taatttaatt
     2641 tgtttatagt tagtgaaggt acgagatatc ctagaaaaat accgagtata ataaaaatta
     2701 tacctaatat accataccag tcctttacat cctgtattgg ttcagatatt ctctggtcat
     2761 ttaatatatc aattatattt gtacgattaa taaattttac agaaagtata aatatgcata
     2821 atgtcacaaa tacactaaat ataaatccat atatgaatcc ttgagttcca aaatgatatg
     2881 tcatttctct ggtatcaata atcactaatt gaaatatttt ccatatacca aaagatacag
     2941 gaatacttaa tataagacct aaaaaacagc atactattga aattaacaat atctctgaaa
     3001 atagaagttt ttttaatttc ttcttatctg ttcctagagc catgaaaata ccaatttcct
     3061 tgcttttaaa ttttaaaaag agggaagaag cgtatgtagt aaagacagcg catcctaata
     3121 tagcaactga gaatatcatt gtagcctgtt ttctgctatc tccaccagtt ggaagtatgt
     3181 tttgtattgt tgggctaaaa taaattagag catatgaagt tactaatacc acagaaagta
     3241 ttatacaaaa gaataaagtt gtatagttct tccaattata ggctcgaagt ttactgtata
     3301 atttattaat tgtcatcttg agcgcctccc atttctttta aaacttctag taattcatct
     3361 aggaatttat gtcttgaatt tgattttaca acttctttat aaattattcc atctttaagc
     3421 acaataactc ggtcacagaa gcttgctgca aagctatcgt gtgtaaccat gagtatagta
     3481 gcatctaatt cttgctttgc ttttaaaaat gattcaatga ctgtacgaca agacttacta
     3541 tcaaggttac cagttggttc atctgctaat attaaatctg ggttgttcat gagtgctctt
     3601 gctactgctg tacgctgttt ttctccacca gatatttcgg cagggtattt ttttctgata
     3661 tgttcaatac caaatagctc acatagatta attgcacggt tttccatttg taagacttga
     3721 ctacctttga taatttgtgg aacacatata ttttcaaaga cactaagacc atcaaatagc
     3781 atgaagtctt ggaatacaaa tcctagttgt tgatttctaa cttctgaaag ttccttttct
     3841 tttaaatttc ttatattatt atttccaaga attatttccc cattatcaat tgggataaaa
     3901 catgaaatac aatttaaaag agtagttttt ccacttcctg atgaacccat gattgcgaca
     3961 aattctcctt tgttgatttc aaaagaaata ttttttaata caggatatgt tttactgcct
     4021 gttttatatg atttacataa ttggtttact ttaagcatat atatcatcct cactttcatt
     4081 tatcttgtaa gtcaatgata gcatttgaaa ggggaggagg gatatgagct atattgtaat
     4141 agttggatgt ttttttgtaa tgtttgaaaa tatattgttt ggatagtgtg agaggttatt
     4201 attatagtta aattgattat attattggag gatttagagg gttattttta ggtattaatt
     4261 gttgtgctaa agtaatatga tgtggaacat tgaaggtgta gttagaaaag aagtatatag
     4321 taaaagtaaa aaggttatag aataacgaat gttgtattga aaaaaatgat gtaaataatg
     4381 tatagtaggg ttaaaaagaa aaaaagaatt atagagcagt aagattattt aatagaatgt
     4441 attgtaaata atttgaaagg atttaggggc tattaacaca atgtaattga gaaaatatat
     4501 tggagttttg gaaataaata ggttgttaga aacaattgaa atgtataata aaaaggttaa
     4561 aaagtattat tagtataggt atgatagata attttagaaa gtggaagtat tttagactat
     4621 gctgaaaagt gattgatatg attttgagat attaaaatat tactatatta tagtaaagaa
     4681 gttaaaataa taaaatgttg taataataaa ggtttgtagt ataataaaga actgtaataa
     4741 ataagacttt gcaatgtaat agaaatgctg taataataaa agtctgtagt ataataaaga
     4801 actgtaataa ataagacttt gcaatgtaat agaaatgctg taataataaa ggtctgtagt
     4861 atagcaaaga actgtaataa ataagagatt gtaataataa aagtctgtag tgtaataaag
     4921 aactgtaata aataagactt tacaatgtaa tagaaatgct gtaataataa aggtctgtag
     4981 tataataaag aactgtaata aataagactt tacaatataa tagaaatgtt gcaataacaa
     5041 aacaccataa taaataagag tttgcaatat aatagaaaca ctgcaataaa taagagattt
     5101 caatataata aaagtctgta atataacaaa atcctataat aaataagatt ttacaatata
     5161 ataaaaatcc tataataaat aggactctgt aatataataa aatgctgtaa caacaaaaca
     5221 ctataataaa taagaccctg taatataata aaaatactat aatatagtaa aaatcatgca
     5281 ataataaaaa tctataataa taaacctcag cataacaaag acattaattt cttactaaaa
     5341 aggccaccac aattaacagt gaaaaagcaa ttgaaagtat tgaaaaagta aaatgagaat
     5401 tagagtcatt attacgatta ttaagtttta tccataaacc acatataatt gtacacaaca
     5461 ataaaattgc tgatattact cctataaatg taaaaaacat taaaattcct cccccttatt
     5521 taatgcaagt atttttagtc aatgagaata ttttcaaacg ttaccataaa ataaaaaaat
     5581 gtacataaaa aattaatata gtattatttt gtaatatcta ccaataataa atctaattga
     5641 aaatctatta aaccatttct ctgttcaata ttaagaatat caataccact atacttgaaa
     5701 aaagcattag aacgaagaaa aagcaactga ataaatgaag ttatttgata cgcaatagtt
     5761 ctgtattcag cttcagtttt tttgttattc tgattttcat agtgagcctt aattaaaggt
     5821 agtatctcaa atggataaac aatttcttcc tgtatcaata tatagggtac agaaatcttt
     5881 ataaattgac tatgttcacc tataaaatca aaaaatgcaa ttagtatttc ccttaattgc
     5941 tgtttaggtg ctaaattttt agtatcatgt gtagccttat attcatccat atgacgcttt
     6001 aaaaattttt taatagaaat attaattaac tcctctttag atttaaaata ataattaatc
     6061 atagctaaat tgacatttgc tttagctaca atttctctag ccgtaatgct tgaaacatct
     6121 ctatgtgaag atagtaactg gattgtggca ttaattaatt gttcctttgt tgaatctgct
     6181 ttcataattt ttccccttaa aagtttcccc ataaaaaaat taaacatgtt taacacacgt
     6241 ttagatacta tcatgaaaat tttgggatgt caatgggtga ttagtactta agtatttaag
     6301 tactaatcta ttagactttt ataaggggga tttgaatttc tgtaagataa ttttcaggat
     6361 ttatttcatt atgttcacct ttatgtccga tttgtctatt tatacctgat atttgataat
     6421 cactattttt atctaaccaa taacagaacg attcatatgc accagctata ttttcatatg
     6481 gaccataaac catagtacat gccatcatat caatttcttc tgtctcacga tatataaatc
     6541 cagatttgtt ctttccaatc ttctttacaa ccattccaac ttcaatatct acaccattat
     6601 ctttgacttc ttcatcatgg taaaaagcta tgttattgtt ggattgacgt gatacttcta
     6661 tatgttcttc tttgataaat ttagatagct tttcccagag tataccttca gattggtagt
     6721 ctggaattat ctctctaagt gatatgattt tataacttgg aatcttttta aagacaacat
     6781 tgtaatgaat ttcatcttta tcacagttta tagcttctat aaatttatca attttattta
     6841 ttctttgttg ttcctgattt atttcctttt gtatttcatt cttttttcta ttcaattctt
     6901 taattacaaa ttcatcattc caattatgta cgatatttgc tatttctgca acgctaaatt
     6961 ttgaatctct caataataca attctttgta gtattgaaat ctgttcaact gagtataatc
     7021 tatgacctgt atatttgtct atttctgcag gttttaaaat accaagttca tcataataac
     7081 gcaacatacg aatagaaatt tgtgttagtt ttgaaacctc tcctatttta aacatgaaaa
     7141 tatgacctcc ttttcactta taatcagtat atattttgtt tttatatact tcaagcgttt
     7201 gtggaaatac aattattttc cagatgttgc aataaattat agagagtaaa ttatatttaa
     7261 gtagtaatcg tatcaaatca tagattatct taatttataa ttcatattaa aattaccagt
     7321 ctaactcaaa ttcaaaatca tccgacttta tctgttcaat ttcagaattt accttctgtt
     7381 taaatttatt agaagaaatc atatatacaa gaaatattaa accaaatatt atttgtacat
     7441 attgagctat tacacataat ttaatagggt agtgtagaag taattgaatg ttgaaaaaat
     7501 agtacatcat atgaactaac ccagctgata aaatgcttct acttgtattg atatatacaa
     7561 aattaattat aaagtttaaa agtacaatgt ttggtataaa taaaaaagca tcaaataggg
     7621 agtattgtgc caaattatat ggtatttgat taggtgtaaa atacgaccct agataccaga
     7681 ttccacaaac aagccctaaa ataattgaag agcctataaa tccaaatcta actaataatt
     7741 tgtcaatggc atatcctctc catccagctt cttgactaag tatactcaat ataaaacttg
     7801 ctaatagcat ataagctatt ttagaaggtc taaacactgc tatgtgtatc caatctatat
     7861 cagaagtttt tacattaaag taatttccga ttattaacga agtaataaaa gttaaagcaa
     7921 aaaataatat tgttaatagt atccatttta ttctaatttc tttaaagctt aggtatctat
     7981 aaataaaatc ttgttttgca ctttgtggat agattgtaga aataaaaaat agacctacaa
     8041 tagctggtga tgtatatgca agataaaaaa tgatttctcc aagtattgta tttgtaattc
     8101 cgagcaacgc aggtgtaaga ctgaatatcc agttcaatac tagcgtaaat gtaaagaaat
     8161 agattaagtg tttgtttgta ttaaaggggg tgttatatag ttgcattttt tcactatcct
     8221 tccgttttat aatgaagttt taatttttat taattgttta tttattttta tatgtattaa
     8281 gttatcgctt gatgttagtt attgcctata ataatatcct attttttata ttttgattaa
     8341 ttatttttac actaaatata attaattagt atttaatatt gaatatatta tattattatt
     8401 aattattaaa taggtcaata aatttgcaat tagtgatatt aataaattac tttagatttt
     8461 tattaaatgt ttagcttttc tttaatattt tttatataac gacgatttat aataactttt
     8521 tcgttgtttt ttaaagtagc ttgcatgcga ttatgtgata ttacttttat actttttatg
     8581 tagtccatat ttaaaatcat ggatttagat attcgtgaga aggatgtatt agctaataat
     8641 tttgataatt tatatatttt taaatcaatt tcaaatacat catcttcata ataagcaaat
     8701 gttttatttc caactgtctc aaagtataaa atatcacaga cattgagttt ataaatctct
     8761 cctgattttt taccttttat atcaagtaac ggtgtactca ataatgaaat tattttttca
     8821 atgttattat ctagagcaga acattttatg gttatttcaa tatcatcaca attaatacct
     8881 tgttcgacat gtattttcat taatcatcac ctcattttat tactgtcatt agaatagcat
     8941 tatatcttat tgagtccaac tagatgcgtt ctaaatttca aattaagcat agtgaaattc
     9001 aaaaataaaa cagtgaaatt caaatttgag gtggtaaaat tcaaaaaaat actatggata
     9061 tttggataaa ttatccaaat atcctagtat ttcacataga atatgtctaa ttattttaca
     9121 aatagaccta ttttatgact tacatatatt gtcaaattac ttcttaaata tcaaaatatt
     9181 tttggataat gtatcaatac tgtttgataa agtatttaat ttaccctcaa ttctaaccaa
     9241 taagtacatg gatagagcta taggaaaacc aacattggtt attaacagtt gtaaactatc
     9301 atccataaaa ttagccccct attctataac taagtcataa ggagtggtat ttgtttccac
     9361 aaccttggct tcaacaacag aagctaggtc aaatcctcca accgaaaaaa tatttttaga
     9421 tactatcaaa tccatgacag attttatatt ttcttcagtt aaatcatcct ttggattttc
     9481 tatagaaaaa gaaacttgtt tatcctttac atttttaaag ctcatgacta attttttctt
     9541 aatttccata taattacctc cgatataata atttatattt taattgtttg cttgttaata
     9601 ttggtatttt aattgtcaat attaatgttt tgcttgttag tattaatatt tcaattgtca
     9661 atattaatgt tttgcttgtt agtattaata tttcaattgt caatattagt gtcttgcttg
     9721 ttagtattaa tatttcaatt gtcaatatta atgttttgct tgttagtatc agtgtttcaa
     9781 ttgtcaatat tagtgttttg cttgttagta ttaatatttc aattgtcaat attagtgtct
     9841 tgcttgttag tattagtatt tcaattgtca atattagtgt tttgcttgtt agtattagta
     9901 tttcaattgt caatattagt gttttgcttg ttagtattag tatttcaatt gtcaatatta
     9961 atgttttgct tgttagtatt agtatttcaa ttgtcaatat tagtgttttg cttgttagta
    10021 ttaatatttc aattgtcaat attagtgttt tgcttgttag tatcagtgtt tcaattgtca
    10081 atattagtat tttaattgtt gactctagtt attgctgata tagaaaatat ttaatttatt
    10141 tcaattaatt agattaaagt agggtagcat ctaaaatagc taacatgttt aagttgaaat
    10201 acgtttaata tattaatttt tcaaagcatt aatatattaa agttataatc aaaattgaag
    10261 ttataatctg ccaaatctat agcgtattaa gtgcgttata taacttaatc ttttatataa
    10321 agagttaatt tttttaattt gtaaagcaga gtacgtttaa aaggtactat ttagataatg
    10381 atgtactatc taattttaaa atatctacaa tagggttctc ttgaagactt gctattgctt
    10441 ctgcaacagc ataaacatct tcatttaatg cctctgcttt tacatttgca aatgatttac
    10501 ttttaacaac tgccttaccc ttatcatcaa aaccagcatc caattttagt tttatactag
    10561 ataaattttt tgttgaaaca acttccataa aattacctcc taaaaattta atttcaaaga
    10621 tttgtcgact ttctttgtta gctataatac tatcatctaa gataatatcg gagttaaaca
    10681 gtaatttcta aagatttttt gtgtaaattt ttataggaaa aattttactt ttttgctgat
    10741 gaaaaagttt acaagttatt tgtgaagata tgttcttagt gttttgaaat agtatttgta
    10801 tatattcatg cttagttgag atagttttgt atggattttc atatgtgtag agttaaatgt
    10861 taggtactaa agtttatgtt aaattaaatg ttaaagctta tgttaaaaat tttattaaat
    10921 ttaatctgta aataaaaaag ttaaaagtcc aatattaaca ttttactttt aaaccattaa
    10981 aatctttatt aaagctaaca aagttataag ttatgagaaa ttttattaaa gttaatacaa
    11041 aaattaattt taaagctaag aaatttttta ttagattcaa taaaactaat aaatatagtt
    11101 tagtcaataa tgtattaaat aaaaactttg ttaagtctat aaaaatatct taaaggaggt
    11161 gtaacttatg aagataaaag tggaggatat accagttcaa tttcatgcaa tggtagaaat
    11221 aattggaatt gataagttta tagaggttgc caagttgtat ggaggaacaa atacttatat
    11281 acctacgtat aaggggcttt ttagatatgc tagaaatagg gatatagtaa aacaatttaa
    11341 tggagtcaac cacaatgaat tggctattag atataatatg tgtgtaagca atattaagcg
    11401 aatactcaat gaaaataatg tttaaatata ataaaataat gtttaaacat aatgaaaata
    11461 gccttgttaa acgtaagagt aaagacaaag aagatgtttt ataaagtttt tttagacaaa
    11521 ttaactaaat ttactactta ttaatttaaa tacattgtat attctataaa aaaatttgtt
    11581 aaatactgga gatatattga gaatacaaag aaaatggtcg aaaatatttg ttggctaaaa
    11641 aatagataaa atgatacaat tgcttgtata aaggggaaaa ataaataaat aaactatata
    11701 aataaagaaa tagcaattaa tatgacataa tatatttata aaattaagaa tataaataga
    11761 tattttaagg tattagttgt taaattagga aatattaaaa aaaatatata tttatattta
    11821 aactattttg ttatttatat aaaaatactt atctagttac tagcaattat tagtagaaat
    11881 gggggaaata gagatgaata agggatttta caaattaaat tcagtggtat tgaactttga
    11941 tattaagaat gatgttaaca agataagatt taatcattat ataatgagaa aagaaaacat
    12001 acaaagactt caaggaactc tgccaaacgg acaattttat atgacagtga gaagagctgc
    12061 tacagattta caactttcta tttctactat aagtaggctt gtaaaagagt ttttggattt
    12121 agggataata agattagtgt ctaagggtgt aaaaggtaat cgttctgtat atagttacgt
    12181 aagtatagag tttaatggaa gtttatttga tgatagcaaa tatatggaac ttgactgtgt
    12241 atgtaatgat gaatttattg ataatagtgg catagagttt gattgtgata gcaaagataa
    12301 ttcttttaat ggagatataa atgtagaaac tgtgcattgc attaatgagt atttgtctga
    12361 tgatgatgta gagcataatt ataacaattt ccataataaa gatactataa aggataaagc
    12421 catttctaat attagcacta tcaaaaaata tattgatgaa tcttttgata aaaataaatc
    12481 agaaaattct aacttacaac aggagtcaat aaatttcaac tttaatgata catgcaatga
    12541 aatagataaa agaacgaata atagtataga aaataatcaa aataaaaggc ctatgagatt
    12601 gagtgacatc agtcttttaa gtgataaagg tatgacaaat aaaaagaatt actttaatca
    12661 taatcatggt atacaaaaag ggactaaatc tgtaacaaag aaaaaagaat ccttaaataa
    12721 atttaataaa aaaaatatac agcaaagcat tataaatatg ctaaataaaa aatcaggtaa
    12781 gaattttaaa atcgattctc caataagcat aaaacttatc aatgaaaggc taaaggaagg
    12841 ctatgtctta gaagatttct acaaagttat tgaggtaaaa gtggctaagt ggaaaaatac
    12901 cataatggaa atgtatataa gaccagaaac tttgtttagc tataagtttg aatcctatgt
    12961 aaatgaaaac atatctatga aaagtcaaag taatgttcac ccatgtaaag aaggcaatag
    13021 taatgatagc agtaattata tacattctga ttatacaaca tatgatggca gtgtgcgtga
    13081 gagaaaaaaa tatgagaatg taagatactg gaatcctata tgtgaaattt aattagttta
    13141 agaatgtatt tatgataaat aagatattaa tagagaatag tgagctatag caaatgatat
    13201 atcaatagtt ggtagtaagt tatattaagc aagatattac tatcaggtag tgaattatat
    13261 tgaacgatat atcaataatt ggtagtaaat tatattaagt aagatattac tatcaggtag
    13321 tgaattatat tgaacgatat attaataatt ggcagtaaat tatattaaat aagatattaa
    13381 tatcgagtaa tgaattatat tgaacgatat atcaataatt gg
//
LOCUS       DAEPHU010000097        13053 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 01A10CD0081
            SAMN05941466-rid12468953.denovo.097, whole genome shotgun sequence.
ACCESSION   DAEPHU010000097 DAEPHU010000000
VERSION     DAEPHU010000097.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941466
            Sequence Read Archive: SRR6291087
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 13053)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13053)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068158.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 22:43:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,892
            CDSs (total)                      :: 3,805
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 87
            rRNAs                             :: 8, 1, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 55
            CDSs (without protein)            :: 55
            Pseudo Genes (ambiguous residues) :: 0 of 55
            Pseudo Genes (frameshifted)       :: 21 of 55
            Pseudo Genes (incomplete)         :: 28 of 55
            Pseudo Genes (internal stop)      :: 16 of 55
            Pseudo Genes (multiple problems)  :: 8 of 55
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13053
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941466-rid12468953.denovo.097"
                     /strain="01A10CD0081"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            326..709
                     /locus_tag="KR231_003297"
     CDS             326..709
                     /locus_tag="KR231_003297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0005635.1"
                     /translation="MSTDKVVGIIDEETAELAGIEYTGKIYASSGVIKHIKKKHRCQL
                     SKDIFNDIIDTIKMVLKSPEYIGSHPKKPGKSVEFIKKIDDYILVATELDTKKGYLYV
                     SSMYAIKEAKLESRVNSGRVKQYDG"
     gene            1217..1600
                     /locus_tag="KR231_003298"
     CDS             1217..1600
                     /locus_tag="KR231_003298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HBH0005636.1"
                     /translation="MNLSKKIEDKRKAKQRAEKVKKAKIATAGVVLGAVTGAVSGVLL
                     APKSGKETREDIKDASQQIAEKINMKTVDVKGKVSEKLEDKKGNFIESKKKIKKYIDN
                     KKSVENSSEEDKIIDIVEPVSVTEE"
     gene            1602..1952
                     /locus_tag="KR231_003299"
     CDS             1602..1952
                     /locus_tag="KR231_003299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428670.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0005637.1"
                     /translation="MDNTITINISIIYVLLAILACIALVYLIIVLVKLHKILNNVGTM
                     LNENTQNINTTLNNLPNVVETFGEVGENMKDVTEVVTEVTADFLVTKDSVKSNMDVIV
                     DILTIIKNIFVDKK"
     gene            complement(2053..2511)
                     /locus_tag="KR231_003300"
     CDS             complement(2053..2511)
                     /locus_tag="KR231_003300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0005638.1"
                     /translation="MIRTKVVELIATVCRENKPHKWVDENYTPYDKSGKVELMSIEDL
                     NELISSSGRADFLYSSRLQKLLNEVYINQSRASYISGCGLFWSSYWDILEEKFEEWLY
                     NSYIFFDEDDEYLEGMEDFELECKDVLMDVIETTSIDIYVQMIKRNITNY"
     gene            complement(2556..3344)
                     /locus_tag="KR231_003301"
     CDS             complement(2556..3344)
                     /locus_tag="KR231_003301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729051.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HBH0005639.1"
                     /translation="MKVVIIPGHTLIGKGTGAVGYINESKETRILNDLIVKWLKIGGA
                     TVYTGRVDESSNHLADQCAIANKQETDLAVQIHFNSNATTSTPVGTETIYKTNNGKTY
                     AERVNTRLATVFKDRGAKSDVRGLYWLNHTIAPAILIEVCFVDSKADTDYYVNNKDKV
                     AKLIAEGILNKSISNSQGGGENKVYENVIVYTGDADKVAAQILHWQLKDSLIIEASSY
                     KQGLGKKVYVVGGEANKLVKGDVVINGADRYETVKLALQEIDKL"
     gene            complement(3483..3920)
                     /locus_tag="KR231_003302"
     CDS             complement(3483..3920)
                     /locus_tag="KR231_003302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine/deoxycytidylate deaminase family
                     protein"
                     /protein_id="HBH0005640.1"
                     /translation="MNKKLENRCSWQEYFMRLCETVAERGTCDRAYVGAIIVNSENRI
                     VSTGYNGSISGDKHCSEVGHEMRDGHCIRTIHAEQNALYYCAKEGISVKNCSIYVTHF
                     PCLNCTKAIIQAGIKHIYYRTGYRIDEYAIKLLQSSNVLYTKL"
     gene            4742..5251
                     /locus_tag="KR231_003303"
     CDS             4742..5251
                     /locus_tag="KR231_003303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBH0005641.1"
                     /translation="MLSENIKTIRKSKGLSQQELAIKLNVVRQTISKWEQGLSVPDSD
                     MLISISEVLETPVSTLLGETIVESEVDNLKVISEKLEIINLQLAQRKNMRRKMFHWLF
                     ILLCAVILIVFVVLGRLNSPYLDWNYTDPETAVFGVAFHAFEWLFVRLVPIVLIGAII
                     GIFLTRKKI"
     gene            5665..6096
                     /locus_tag="KR231_003304"
                     /pseudo
     CDS             5665..6096
                     /locus_tag="KR231_003304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016295744.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
     gene            complement(6283..6476)
                     /locus_tag="KR231_003305"
                     /pseudo
     CDS             complement(6283..6476)
                     /locus_tag="KR231_003305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227347.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
     gene            6578..7084
                     /locus_tag="KR231_003306"
     CDS             6578..7084
                     /locus_tag="KR231_003306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HBH0005642.1"
                     /translation="MKNEKKITVALLIVYLLILSWIILFKLQFSFSALDHIRQINLIP
                     FGGSVIANGKIDFDEIINNAIVFIPVGAYFSLLFKNKSVLKAIGSVLGISFVYEIIQF
                     IFAIGASDITDLISNTLGGIIGIALVYVLSIVLKDKTHKILNRIAIVCTVLVVAFLFM
                     LLAVNNIF"
     gene            7089..7365
                     /locus_tag="KR231_003307"
                     /pseudo
     CDS             7089..7365
                     /locus_tag="KR231_003307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436830.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4865 family protein"
     gene            7634..8206
                     /locus_tag="KR231_003308"
                     /pseudo
     CDS             7634..8206
                     /locus_tag="KR231_003308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902350.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
     gene            8309..9124
                     /locus_tag="KR231_003309"
     CDS             8309..9124
                     /locus_tag="KR231_003309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="effector binding domain-containing protein"
                     /protein_id="HBH0005643.1"
                     /translation="MFKIGEFSKLTQVSTRMLRYYDETGLLKPAKIDSLTGYRMYSAE
                     QISTLNRIIYLRDSGFNVAEIALALNFSNNAIIEQLDRKSIEIMDNIQKEQEKLKKIE
                     IAKKEVLHGKSELYFNITIKEIPSYCVLSLRKEIPNYYYEGELWKELSAFAKENKINI
                     SDETFSIYHNEEYKEKDVDVELCAIVNKIGKATGDFKFRFTEPVSMMACTMVYGDFSN
                     ISYAYRSFAKWLQENSQYKMKGSSRQIVHRGPWNEKNPENYLTEIQIPLENLL"
     gene            9205..9681
                     /locus_tag="KR231_003310"
     CDS             9205..9681
                     /locus_tag="KR231_003310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002608187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAM-dependent methyltransferase"
                     /protein_id="HBH0005644.1"
                     /translation="MTTYKVNSIGTICNNEKGAFIQLEAPYILALRALDGFSHINVLW
                     WFSDFDNTNFRSVLETEQPYKNAPEKMGIFATRSPVRPNPIALSAVEIIDIDYMSGLI
                     QIAYIDANDKTPILDIKPYTPSLDRVENPQVPDWCSHWPHSLEESASFAWESEFNF"
     gene            9695..10258
                     /locus_tag="KR231_003311"
     CDS             9695..10258
                     /locus_tag="KR231_003311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBH0005645.1"
                     /translation="MSLQDYIFEKPVIETEHLILRTMNKNDIDDLKEWISDISLYEYW
                     GKRPSKSEKNPELLFDKSKKSTKSFHWGIVHKQDSKVIGEIWIYLIENNRMAKVAFRL
                     SKHYQGNGLMSEVLKNVIEFCFSKTELQKIWTDVHILNHASYKTLEKVGFQREGHIRG
                     GKMVNTYCDYYLYGILKSDYITRWCYG"
     gene            10513..11424
                     /locus_tag="KR231_003312"
     CDS             10513..11424
                     /locus_tag="KR231_003312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HBH0005646.1"
                     /translation="MYAYENIEMSLNYIEQHLSEKIETEKLAEIACLSTFYYQRLFKR
                     LVKKSVQEYIKLRRLAMVIAELNNSEERILDIALKYGFSDHANFTRAFKEVYHITPDE
                     YRKNVPMLNTFDKPELSSRYIMIDENVPLIVGNIVLEIQRKTLRTKETYFGFEKTVNI
                     SEQIPAGESTGIDVPGQLWREFHAKKLQTENAIFNNDIELGVSHLASPDKGTFLYFAG
                     GMVSSTDVCPKNMVQHTLPAGEYIVCKIEAESFEELVTTALNQANKYLFETWLPNHNL
                     VTKPFMAEKYYKGNAEINYMEIWIIPV"
     gene            11502..11936
                     /locus_tag="KR231_003313"
     CDS             11502..11936
                     /locus_tag="KR231_003313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3788 domain-containing protein"
                     /protein_id="HBH0005647.1"
                     /translation="MINIKDINYVPNISEISVYIENSAFDELYQHMNNEYKAVCKIEY
                     SKDVWARGWNVKFKKSGKSLCVVYPKKNYFTVLVVVGNKEKEDVENLLPRLSEYVQEI
                     YRNTREGNGQRWLMIDLKSKNNVYQDVLRLIEIRYAIKCVKP"
     gene            12404..13053
                     /locus_tag="KR231_003314"
                     /pseudo
     CDS             12404..13053
                     /locus_tag="KR231_003314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009243519.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="C40 family peptidase"
BASE COUNT         4732 a         1842 c         2193 g         4286 t
ORIGIN      
        1 ttttatatat aaataatatt atcacagaaa actttaaaag aaaacgtttt atataatata
       61 gacaatagat tatattttta taaagaagca agaatactca ataaaactta aagaaattaa
      121 acgatttcta aaaatacctt gaaaatagaa ccttatttgc catttataaa ttatataaaa
      181 agggattata taaagtcata tatgaaaaaa ctatattata ctatcttttc tttttggaat
      241 aaactatact ttaaatatag atatttaatt taaataaatt ttacagtatt aatagtaaat
      301 tatcttagaa aggaatgtgc tttatatgtc tacagacaaa gttgttggaa tcatagatga
      361 agaaacggca gaacttgcag gaattgaata tactggtaaa atttatgctt cttctggtgt
      421 tataaaacat ataaagaaaa aacatagatg tcaactgagt aaggatattt ttaatgatat
      481 aatagacact ataaaaatgg tattaaagtc acctgaatat ataggaagtc atcctaaaaa
      541 acctggaaaa agtgtggagt ttataaaaaa aattgatgat tatattttag tagctacaga
      601 attagataca aaaaaaggat atttatatgt atcttcaatg tatgctataa aagaagcaaa
      661 attagaaagt agagtaaaca gtggaagagt aaaacaatat gatggttaac ataatattat
      721 taattttccc taaaatattg aaaaatatta ttatataagt tataatatta atatacacgt
      781 agatatttat tagttagatt tgaggttgga aaaggcaccc aatacgctac tatagagtag
      841 ttaatagaga tgcaggatac gccgccctgc caaatctaat taaattaaaa agagaggatt
      901 aattcctctc ttattgtttt tttgagatac taatttaatc tataatagaa agattgaagg
      961 tcgtttatac aaaaaaattt tcagttatat acattaaact aattaaataa gatatttata
     1021 atctatatgt gatacatatt atatattaat aaaagaaaaa tatatagaaa atccttataa
     1081 aaatttaaat tgtaatgaat aggaagtaat taaaaagaat ttttattgat ttttaaaaat
     1141 ttagttagaa actatatcat tatggtaaaa aatgtattat aatgtttaga aatattataa
     1201 taaggagcga ttaaacatga atctatcgaa gaaaatagaa gataaaagaa aagctaaaca
     1261 gagagctgaa aaagttaaga aagctaaaat tgctacagct ggtgtggtat taggagctgt
     1321 tactggtgca gtgagtggag tacttttggc tcctaaatct ggaaaagaaa caagagagga
     1381 tataaaagat gcttcacaac aaattgctga aaagataaat atgaaaactg tagatgtaaa
     1441 aggcaaagta tctgagaagc tagaggataa aaaaggaaac tttatagaat caaagaaaaa
     1501 aataaaaaaa tatatagata acaaaaagag tgttgaaaat tctagtgagg aagataaaat
     1561 aatagatata gttgaaccag ttagtgttac tgaggaataa tatggacaat acaataacga
     1621 ttaacataag tataatatat gtattattag ctatacttgc ttgtattgct ttagtttatt
     1681 taattattgt acttgttaaa ctacataaga ttttaaataa tgttggaact atgttaaatg
     1741 aaaatactca aaatataaat acaactttaa ataatcttcc taatgttgta gaaacttttg
     1801 gagaagtagg agaaaatatg aaagatgtaa cagaagtagt tactgaagtt acagcagatt
     1861 ttcttgttac taaagacagt gtcaaatcaa atatggatgt tatagttgat atattgacta
     1921 taattaaaaa catttttgta gataaaaaat aataagttaa tataaaataa gcctataaga
     1981 tataatttaa acgaccttaa aatagcattt ataaggtcgt tttttattag cttgatttga
     2041 cactatgtgt ttttaataat tggtaatatt cctctttatc atttgaacat atatatctat
     2101 gcttgttgtt tcaattacat ccataagaac atctttacat tcaagctcaa aatcttccat
     2161 tccttctaaa tattcatcat cttcatcaaa aaagatataa gaattatata gccattcttc
     2221 aaatttttct tcaagtatat cccaatacga actccaaaat aatccacaac ctgatatata
     2281 agatgctcta ctttgattta tataaacttc atttagaagc ttttgtaatc tactgctata
     2341 aagaaaatct gctcttccac tgcttgatat taattcattt aaatcttcta ttgacattaa
     2401 ttcaacttta ccacttttat cataaggagt ataattttca tcaacccatt tatgtggttt
     2461 gttttctctg catactgttg ctatcaactc tacaactttt gttcttatca tttttttatc
     2521 ctaacttatt tattttttat aaaataatca tgattttata atttatctat ttcttgtaat
     2581 gctaatttaa cagtttcata tctatcagca ccatttatta ctacatcacc ttttacaagt
     2641 ttattagctt ctccacctac aacataaacc tttttaccta aaccttgctt ataactagac
     2701 gcttcaatta ttaaagaatc tttcaattgc caatgtaaaa tctgagcagc cactttatca
     2761 gcatcacctg tataaacgat tacattttca tacactttat tttcccctcc cccttgagaa
     2821 tttgatatag atttgtttag tataccttct gctatcaatt tagcaacttt atctttatta
     2881 ttaacataat aatctgtatc tgctttacta tctacaaaac atacttctat taatattgct
     2941 ggtgcaatag tatgattaag ccaataaaga cctctaacat cagactttgc acccctatct
     3001 ttgaatactg tagctaacct agtattcact ctttctgcat aggttttgcc attattagtc
     3061 ttatatattg tttctgtccc tactggagtt gaagttgtag catttgaatt aaaatgaatc
     3121 tgaacagcca aatcagtttc ctgtttattt gctatagcac attggtctgc taaatgatta
     3181 cttgattcat caactcttcc tgtataaaca gtagctccac ctattttaag ccatttaaca
     3241 attaagtcat tcagtattct tgtttctttg ctttcgttta tatacccaac agctcctgta
     3301 ccttttccaa ttaaagtgtg ccctggtatt attactactt tcaaactaac atctccttta
     3361 caattaaatt taacttctat ttaatatatg cataacctag aattttgttt ctttttatat
     3421 cttatacttt tattataacc cattttgtaa aaatatagaa tattaagtaa ataatgttaa
     3481 aattataatt ttgtatataa gacattactt gattgcaata attttatagc atattcatct
     3541 attctatatc cagttctata atatatatgt ttaattccag cttgaattat agccttagta
     3601 caatttaagc atggaaagtg agttacataa atagagcaat ttttaactga aataccttct
     3661 tttgcacaat aataaagggc attttgttca gcgtgaatgg ttctaataca atgtccatct
     3721 ctcatttcat gaccaacttc actacaatgc ttatctccag aaatactacc attatatcca
     3781 gtagacacta ttctgttttc tgaattgaca attatagctc ctacataagc tctatcacaa
     3841 gttcctcttt cagctactgt ttcgcacagt ctcataaaat attcttgcca tgagcatcta
     3901 ttttcaagtt ttttattcaa atcatatacc tccaaaattt atatctaata tataagattt
     3961 ataccttaaa aataatatta aaaacaaatt tatatgataa ataaaattta ttaatactgt
     4021 ttttagtcta aattatttca ttttaaatta aagttacaag gaatctaaga ttatatatat
     4081 ctttcttcgt aatatgaatg ttacaatata aaaaactgtc tcaataaaat agagacagtt
     4141 ttacagtcaa agtttataat acaagttcat atttttcttt aaattctttt acagcttcgg
     4201 gccatgcctt ttgttctgta ataccttttt ctttagctat tttaattgca atctctctta
     4261 tcattgcagc gccttctaat attcccattt ttaatctccc ttcaaatatc tttttgtata
     4321 gaatataaat agtgctaaga tttattacat gctgcatata caatatctat acaacacata
     4381 acttgtaaat tccttttatt ttcatacgtc tttaaccgac atataattat attcaataag
     4441 ttttaaaatt atgaactcaa ttataattat ttttattttt ttagaatcta aacactaaaa
     4501 attgtaggta aatttgtctt atgcctttat aaatatttct acagttttaa ttactggaca
     4561 tatctatttt tattataaaa agcgattaaa aatggagaat atcctcataa aaactatata
     4621 taagcaaaac ggttaaagga aaaagaagaa atttacttga atgttaaaat gcgttgcttg
     4681 aagcaatggg cagttttgcc tataatatcg gtaacaactg aaagaaaggt ggttagccct
     4741 aatgttaagc gaaaacatta aaacaatcag gaagtcaaaa ggactttcac aacaagaact
     4801 tgctataaaa ctgaatgtag tgcgacaaac aatatctaaa tgggaacaag gactgtcggt
     4861 tcccgattct gatatgttga tttccatatc agaggtgctt gaaacgcccg taagcacttt
     4921 acttggagaa actattgttg agtcggaagt tgataactta aaagtgattt ctgaaaaatt
     4981 agagattata aacttgcaac ttgcacaaag aaaaaacatg agaagaaaaa tgtttcattg
     5041 gttatttatt ttattatgtg cagtcatatt aatagttttt gtggtcttag ggagactaaa
     5101 tagtccttac ttggattgga attataccga ccctgaaacc gctgtttttg gagtagcttt
     5161 tcatgctttt gagtggctat ttgtcagatt agtaccgatt gtccttatag gagcaattat
     5221 tggaatcttt ttgacacgta agaaaatatg aagtaactct gctttttata atacagcaag
     5281 cgttccttaa aagcgtcatt ctacatggca atcgaggacg actatgtaag gaagaacctt
     5341 tttgatttcc aactaagcga agttattgag gacgacagta ggcccaaaac cgcattaagt
     5401 aaagtacagg aagcaagact gctggactta tactctcatg cgtcagatgc aggaaatgcg
     5461 aggtctggta gcatgattta caacgatttg tacaacgact acgagtagaa atatatggag
     5521 ataagtatta tctacgaaat cagaaaagaa atgacttgat aatttactca tgttataatt
     5581 attgatgtga aattaataaa tcgaaattcc ttttttggat ttaacaatac tgagtaagga
     5641 aaaagtgaat tacttttgca aggaggtgtt atttggatgg tgctagcagg tattttgatt
     5701 gtagtacaag gctttttgac tggtccttta gcaaaaaaaa ttggtgagaa gcgactaata
     5761 ctgataggta tgttttgcaa agccttagta gcgtttgcca tggtattgac aactgggttt
     5821 gttagtgtgt tggtggtttt tggcttattt gcggtatctt ctgctattac agtacccaca
     5881 ttaaacgcaa ccctttcaaa aactgacaat cagcataaag gaacactgat gggatttgcc
     5941 agtaccgccg gaaatcttag caaagttatt gctcctttat taactgggta tctgtatgaa
     6001 agcaatattg aattaccata tataaccacg ggagggatag ccttaatcgg agtggttatc
     6061 tgctatatct ggataaaaaa tcaaaagaac aaatgatgga agaggacgtt tatatggagg
     6121 ttatacacag taactaatct ggtatagaaa ttcaattgag gcttttctgc tttattaaag
     6181 tcttgctact acttaaccct ataatatcct taattcatta tgacaaattc caattcaaca
     6241 gttttgatac acataaggag gtaacaatac tatggaaaat tatcaatgaa gtgctaattc
     6301 tttatcagtg aagttatcca taagtttttc tacctgtaat cgtctggtgc tttttgccag
     6361 atcattggta ggtaagaaaa attcatcaac agacacatga agtaatgata caaggtcact
     6421 tgtatgcttg gatgttgccc tttattttca atattagtta agtaacgtgg gtcaatattt
     6481 gtaattcgat tttagggaaa tatttaaaga aatattttcg ttttatttct ttaaatcttc
     6541 aagaatattg atagtttttt gaaagtaggt gtgtattatg aagaatgaga aaaaaattac
     6601 agtcgcattg ctcattgttt atttattgat tttatcatgg attattttat ttaagctaca
     6661 attttcattt tctgcgttag accacataag acaaataaac ttaattcctt ttggtggttc
     6721 agttattgca aatggaaaaa ttgacttcga tgaaattata aacaatgcca ttgtttttat
     6781 ccctgtaggt gcatatttca gtttgctttt taaaaataaa tctgttctaa aagcaatagg
     6841 ttctgtttta ggaattagct ttgtatatga gataattcaa tttatatttg ctatcggagc
     6901 aagtgatatt acagacttaa ttagcaacac attagggggt ataattggaa ttgcattagt
     6961 atatgtatta tctattgttc taaaggataa aacacataag atattaaatc gaatagcaat
     7021 agtatgtact gtattagtag ttgccttctt atttatgctt cttgctgtaa ataatatatt
     7081 ttaatgccat gttaattaca tgttgttttg gaaaagactt taatctgtca aagtttgctt
     7141 ttgaaattga acatgaaatt acaccaatgg aacaaatgaa agctataaat ttttcattgg
     7201 agaaagatga ctgtacaagt aaagtattaa tatacaatcc agacaaatgg aaatatgtag
     7261 aatactattt ctataaagat agacctatta aaaaaactat tggaaaaatt tattcaattt
     7321 tgcatttgtc acaataaaat atgttttgaa atattgaata cttaaatatg caaaaaaaca
     7381 aatgtaactg gctatggggc tatatctact aaaaagctat gtgataggtt gggattaaat
     7441 ttaaacatca cttctagaag gcatgaatac acaaggctga caaactatac agttatgatt
     7501 aaacgatacc aacgggattg aaaatttcgt gaagaacttt gagaagtcct attacacatg
     7561 agcaacagca acgaagctat tgaagcaagg acgcaggcaa tctagcggtt atctgacaaa
     7621 ggagttgtag gacttgaatg tagatactat cagaacggat ataccgacca gctctgcggt
     7681 tacagatgtg attgtgtaga atatcgagca gtcgggaacg gacactttat ctgctaccta
     7741 cgaagtagat cagcagataa aagagagaga acagacaaca gcggtcaagg caacctatac
     7801 cgtaaaagtc catgtggacg ctgacgggga tatggtaatc gttcagaacc ttactcttgc
     7861 accagcaatc gaaaaatcag actatgagcc aaagatatca gaaacagacg caagcgtgga
     7921 cgctgatacc gttaatgacg ctaccgcatt tctggaaaca ttctttgagg tgtacccgac
     7981 agccacagaa aaagaacttg cctattatgt atcggaaaat gtgattgaac ctatcggcag
     8041 ggactacctt tattctgaat tggtaaaccc agtctttaca aaggacgggg acaatgtgaa
     8101 agtcaaggta gctgtgaaat tccttgataa tcagacaaag gcaacgcagg tgtcgcagta
     8161 tgatcttgta ctccaaaagg atagcaactg gaagatttta ggataacatg gaaatgggct
     8221 tgtatcataa ttatagtgtg caagcccttt tcatattgaa gtatcaataa tcaataatta
     8281 taattaggta catgaatgga gggataaaat gttcaaaatt ggtgagtttt caaaattgac
     8341 acaagtttct actcgtatgt tgcgttatta tgatgaaacg ggtttattaa aacctgctaa
     8401 aattgattca ttaactggat atcgtatgta ttcagcagaa caaatctcaa ctttaaatag
     8461 aattatatat ttacgtgata gtggcttcaa tgtcgctgaa attgcattag ccctcaattt
     8521 cagtaataat gccattatag aacagcttga tagaaagtct attgaaatta tggataatat
     8581 acaaaaagaa caagaaaaac taaagaaaat tgagattgct aaaaaagaag tgttacatgg
     8641 caaaagtgaa ttgtatttta acataaccat taaagagata ccgagttatt gcgttttatc
     8701 tttaagaaaa gaaataccaa attattatta tgagggcgaa ctctggaaag aactctctgc
     8761 ttttgctaaa gaaaataaaa taaatatttc tgatgaaaca ttctcaatat atcacaatga
     8821 agaatataaa gaaaaagatg ttgatgtaga attatgtgcc attgtaaata aaataggaaa
     8881 agctacagga gattttaagt ttcgttttac cgaaccagtt tctatgatgg cttgtactat
     8941 ggtatatgga gatttttcta atatttctta tgcttatcgt tcatttgcaa aatggcttca
     9001 agaaaacagt caatataaga tgaaaggttc aagccgtcaa atagttcatc gtggaccgtg
     9061 gaacgagaaa aatccagaga actatctaac agaaatccaa attcctttag aaaatctctt
     9121 gtaaaaaatg ataatctgcc ttgactttaa catggtgtta aggtttatcg tttatttatc
     9181 aagaagaaaa cggaggaaaa tataatgaca acttataaag taaattcaat aggtactatc
     9241 tgcaacaatg aaaaaggtgc tttcattcaa ctagaagcac catatattct agcattaagg
     9301 gcattagacg gattcagtca tataaatgtt ttatggtggt tcagtgattt tgataatacg
     9361 aattttagaa gtgtattgga aacagaacag ccttataaaa atgctccaga gaaaatgggg
     9421 atttttgcaa caaggtcgcc agtacgccca aatccgattg ctttatcagc agtagaaatt
     9481 atcgatattg attatatgag tgggctgata caaattgctt atattgacgc taatgacaaa
     9541 acgcctatct tggatattaa accatacacg ccgagtttgg atagagtgga aaatccgcaa
     9601 gttccagatt ggtgtagtca ttggcctcac agcttagaag aatctgcttc ttttgcatgg
     9661 gaaagcgaat tcaattttta aggagtgatg aaccatgagt ttgcaggact acatttttga
     9721 aaaaccagta attgaaacag aacatcttat tttaagaaca atgaataaaa atgacataga
     9781 tgatttgaaa gaatggatta gtgatatttc tttatacgag tattggggga aacgtccctc
     9841 aaaaagcgaa aaaaatccag aattactctt tgataagtca aaaaaatcta ctaaaagttt
     9901 tcattggggt attgtccata aacaagatag caaagtgatt ggtgaaatat ggatatatct
     9961 tattgaaaat aatagaatgg caaaagtggc tttcagactt tctaagcatt atcaaggtaa
    10021 tggactaatg agtgaagtgt tgaaaaacgt aattgaattt tgtttttcaa aaacagaatt
    10081 acaaaaaata tggacagatg tgcatatttt aaatcatgct tcttacaaga cattggagaa
    10141 agtcggtttt caaagggaag gacatattcg aggggggaaa atggtaaata cctattgcga
    10201 ctactaccta tatggaattt taaaatctga ttatatcact aggtggtgct atggctaata
    10261 ttgaagcgac gattggcgaa gcaatgaaca atacagttcc aaaggtctat gatacgaaaa
    10321 gcattaaaag atatgtgatg aatttattag atatggctca ttaaaaagta ccaaagaaat
    10381 aaaagttacc atatagacaa aattggtttt ttatatcttt tgatttctta taagataatg
    10441 gcattgtgcg acaagctatg caaaaaattt tcatgtatac tttgattata atttatacaa
    10501 ggaggtactg atatgtacgc atatgaaaat attgaaatgt cattaaacta tattgaacaa
    10561 catttaagtg agaaaatcga aacagagaaa ctggcggaaa ttgcctgtct ttctacattt
    10621 tattaccaac gcttgtttaa aaggttagtt aagaaatcag ttcaagagta tatcaaactt
    10681 cgccgtttag caatggtaat agcagaattg aataattcag aggaaagaat attagacata
    10741 gctttaaaat atggattttc agaccatgct aacttcacaa gagcatttaa agaagtttac
    10801 catattactc ccgatgaata cagaaagaat gttcctatgt taaatacatt tgacaagcca
    10861 gaactttctt cacgttatat catgattgat gaaaatgtcc cattgattgt aggaaatatt
    10921 gttttggaaa ttcaaagaaa aacattaaga acaaaggaaa catattttgg ttttgaaaaa
    10981 acagtaaata tttctgaaca aattcctgct ggagaaagta caggaattga tgttccaggt
    11041 cagctatggc gcgaattcca tgcaaagaaa ctgcaaaccg aaaatgccat ttttaacaat
    11101 gatattgaac ttggtgtatc tcacttagca agtccagata aaggaacatt cctttacttt
    11161 gcaggaggta tggtttcatc aacagatgta tgtcctaaaa atatggtaca acatacatta
    11221 ccagcaggtg agtatattgt atgcaaaatt gaggcagaat cttttgaaga acttgttact
    11281 actgctttaa atcaagcaaa taagtatctg tttgaaactt ggcttccaaa tcataatttg
    11341 gttacaaagc cattcatggc agaaaaatat tacaaaggaa atgcagagat taattatatg
    11401 gaaatatgga taattcctgt gtaaacagta aatgctaaat aggaattatc tgacgtaata
    11461 aaaaggaaat agaaagctta taaaggaggg catagtccgt tgtgataaac ataaaagata
    11521 taaattatgt acctaatatt agtgaaataa gcgtttatat tgaaaactct gcatttgatg
    11581 agttgtatca gcatatgaac aatgaatata aagcagtttg caaaatcgaa tacagtaaag
    11641 atgtctgggc acgaggttgg aacgtaaagt ttaaaaaatc tgggaaatca ttgtgtgttg
    11701 tctatccgaa gaagaactac tttactgtat tggtggttgt aggtaataaa gagaaagaag
    11761 atgttgaaaa cttgttacct aggctttctg aatatgtaca ggaaatttat cgtaacacta
    11821 gagagggaaa tggacaaagg tggcttatga tagacttaaa atctaaaaat aatgtatatc
    11881 aagatgtatt aaggcttatt gaaattcgtt atgccataaa atgtgtaaaa ccgtaataaa
    11941 aatatttttc acatacgtaa tctcaaggta ttatcgttga gacaagtaac ctatataatt
    12001 atgggaaatg agatttttag atacttaaga aagtacttta gggggcttgc gttatggaaa
    12061 gatttaagta caattccaca caatcaaata caatctaata aaactttact aaaaattgaa
    12121 tgcaatacag ctttaaaggc tcgtacaaac tatatgtttt gtgcgggctt ttttcattta
    12181 ataggaattt ggattcgtca gagagtatat tataaaaata aaacgataag ggtaccttaa
    12241 aaataaggta cctcaggctg tagacaaagt cccggactct cgtctgggct tttcttatat
    12301 ttgagttatc cacaattcaa ctttttaaga gttatcttat taagaaaaaa gtgtatgttt
    12361 tccaccctat agttttactt ctgtgatatt tgcagatgcc actcaagtag aaagtggtgg
    12421 tacggcagaa gatgtcatgc agagttcaga aagtctggga ctaccgccta attccttaga
    12481 cacggaaagc tcaatcaagc aggggtgtaa gtattttgcg tccctgcttt cttcctgcaa
    12541 aaatcaaggt atcgacgatt tgaatgtagc gatacaatct tacaactatg gcgggggtta
    12601 tgtgggctat gtggcaggaa aagggaaaaa gcacactttt aatcttgcag agagcttcgc
    12661 ccgtgagaaa tcgggtggaa agaaagtaac ctacgccaac ccgatagccg ttgcaaagaa
    12721 cgggggctgg cggtatggct atggaaatat gttttatgtg gaattagtca atcagtattt
    12781 aactgttccg caggtatcgg gagagctggc acaaaaggta atgaatgaag cgttgaagta
    12841 tcaagggtgg aaatatgtgt ttgggggaag caatcccaac acttcctttg attgtagcgg
    12901 acttgtgcaa tggtgctatg gaaaagctgg tatctactta ccgagaacgg cacaaacaca
    12961 gtatgacgca acccagcata tccctttatc gcaggcaaaa gctggggagt tgttcttttt
    13021 ccattcaacc tataacgctg gttcgtatgt aac
//
LOCUS       DAEPHU010000098        12609 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 01A10CD0081
            SAMN05941466-rid12468953.denovo.098, whole genome shotgun sequence.
ACCESSION   DAEPHU010000098 DAEPHU010000000
VERSION     DAEPHU010000098.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941466
            Sequence Read Archive: SRR6291087
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 12609)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12609)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068158.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 22:43:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,892
            CDSs (total)                      :: 3,805
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 87
            rRNAs                             :: 8, 1, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 55
            CDSs (without protein)            :: 55
            Pseudo Genes (ambiguous residues) :: 0 of 55
            Pseudo Genes (frameshifted)       :: 21 of 55
            Pseudo Genes (incomplete)         :: 28 of 55
            Pseudo Genes (internal stop)      :: 16 of 55
            Pseudo Genes (multiple problems)  :: 8 of 55
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12609
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941466-rid12468953.denovo.098"
                     /strain="01A10CD0081"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            134..1630
                     /locus_tag="KR231_003315"
     CDS             134..1630
                     /locus_tag="KR231_003315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S dicluster domain-containing protein"
                     /protein_id="HBH0005648.1"
                     /translation="MFEFETQLKRLKHEVLTAVARLSIEENLTKENIEKIPYEIIKGE
                     KARYRCCVYKEREVVLERAQLALSLTPNSKYGDINPDSVSLDTDEQIIYIVEAACDRC
                     PINEFTVTELCRGCLAHRCKEACKFGAISYINGRAYINHDLCKACGMCKSSCQYDAIS
                     EVVRPCKSVCPTGALDFNRNTMKAMIHEDNCINCGACMSACPFGAISDKSLIAPVAKK
                     LAKKENMYAIVAPAITGQIDSNITYGQLKNAIKSLGFVDMIEASCGADAVTVHESNEL
                     IERIKSGDNYMTNSCCPGFFKYIEKMFPDEKDRISSTVSPMVATGRLVKKIDSDAKVV
                     FIGPCTAKKSEATEKSLKDSVDYVLTFEELMALFEAFNIDLSKCSNEDINDGSIFGRG
                     FGASGGLAKSVQNYIAEKGLSFDFEPIKVSGPRQIKKTMTMAKLGRLEGNFIEGMMCE
                     EGCINGAGKFLSGVKAKNTFDRKNGQSTKKSVLSNDKIKEFEDVNLER"
     gene            1764..2678
                     /locus_tag="KR231_003316"
     CDS             1764..2678
                     /locus_tag="KR231_003316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HBH0005649.1"
                     /translation="MRKIVLKDILFLVTTLSIIVILLLVTNITTNSKIKSTNESYLKS
                     DKNDVSQNNIQSSTKNTAFKTTILSTGKSDCILVEIGNKVIMIDTGEDKNGKQIVDRL
                     KEKGINTLDYLILTHLDKDHIGGVDSVLSSVKVKNIIQANYKKDSKQYDEYIDSLKKA
                     DIEPVLLKDNMNIVINSAEINIHPASKSKYESSNDYSIITNISYGAHKFLFAGDAEEE
                     RLSEFINGNTLKYDFVKMPHHGRYDKLTETFLESISPQYAVITCSEKKEPEEGVLKIL
                     ERLNIKTFLTSNGEVVINSDGKTLSVNQ"
     gene            2796..2987
                     /locus_tag="KR231_003317"
     CDS             2796..2987
                     /locus_tag="KR231_003317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0005650.1"
                     /translation="MLDRFFGEGGFGGCAWWIIILFFLFLAFQDCWAEMDLCAWIPFL
                     ILLLILCECGDVFDGGCGC"
     gene            3210..3560
                     /locus_tag="KR231_003318"
     CDS             3210..3560
                     /locus_tag="KR231_003318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0005651.1"
                     /translation="MAIVDKIFNEIKLMVARLLLGKKYSEYEEKDLVYNTEEEVILIT
                     LKRLVFQGNVNEAEEILFDKAKSVNSENMQYIAIEFYTMLMEKTDEELEAMNFSKQEV
                     YQGIEDIRKVLNLE"
     gene            3822..5327
                     /locus_tag="KR231_003319"
     CDS             3822..5327
                     /locus_tag="KR231_003319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003374392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1846 domain-containing protein"
                     /protein_id="HBH0005652.1"
                     /translation="MKVGFDHKKYLEEQSKYILERVNNFDKLYLEFGGKLMGDLHAKR
                     VLPGFDENAKIKVLQHMKEKVEVVICVYAGDIERNKIRGDFGITYDMEVLRLIDDLRG
                     YELDVNSVVITRFEGQPATTVFINKLERRGIKVYKHYPTKGYPSDVETIVSDEGYGAN
                     EYIETTKPIVVVTAPGPNSGKLGTCLSQLYHENKRGNVVGYSKFETFPVWNVPVKHPL
                     NIAYEAATVDLKDVNMIDSFHLETYGEMSVNYNRDLELFPVLKKIIEKITGKESIFQS
                     PTDMGVNRVGFGIIDDEVIRKASIEEIIRRYFKTACEYKKGQVDKGAYDRMKMIMEEL
                     NLKPEDRNVVLPARNYSNKLKESADKNDTCPVVALELEDGTILTGKGSDLMNGTAAVV
                     LNAIKHLANISDDMHLISPVILEPIINLKTKTLASRNVSLSCQEVLTALSICAVTNPT
                     AQFAMEKLALLKGCQAHSTTILNRDDEQTFRKLGIDVTCDPEYPSQNLYYS"
     gene            5717..6814
                     /gene="dinB"
                     /locus_tag="KR231_003320"
     CDS             5717..6814
                     /gene="dinB"
                     /locus_tag="KR231_003320"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase IV"
                     /protein_id="HBH0005653.1"
                     /translation="MKHYRKIIHIDMDAFYASIEQRDNKKLKGRPVIVGGNPQSRGVV
                     ATCSYEARKFGIHSAMPSAVAYNRCPYAVFVRPRFDVYKSVSEQIRDIFYRYTDLVEP
                     LSLDEAYLDVTKNKKNIDSSIEIAKQIKKDIFREVGLTSSAGVSYNKFLAKIASDLRK
                     PNGLTVITEENAQDFLDKLPVNKFFGVGKVTSNTLKNLGIKTGYDLRCLNLFELENIF
                     KKRGYELYKFARGIDDRPVEPNRVRKSVGAETTLSHNLDIDEEETRNILDELCEEVCH
                     RLKNSEKFGKTLTLKIKYEDFTKITRSLSLEHYIDEYNDIRSGVDNLLRNVDVNGKQI
                     RLLGVTISNLSDKKETYKDITLFEYMDSIQM"
     gene            7077..8213
                     /locus_tag="KR231_003321"
     CDS             7077..8213
                     /locus_tag="KR231_003321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH0005654.1"
                     /translation="MIEIRNVTKKIGNNVILDDISLVVETGTLVVLIGSSGCGKTTTL
                     KLINKLIKPTSGEIYINGKPISQENEIELRRKIGYVIQNTGLFPHLTIKENIELIPRL
                     KKEKSVEEIEKRTLQLLEMVGLDSDEFLNKYPSELSGGQQQRIGVARAIATDAEIILM
                     DEPFSALDPITRTSLQEQLFSLQDELKKTIIFVTHDMDEALKIADKICIMKDGRIAQY
                     DTPENILRKPANDFVKDFIGEDRVWDNPEYIKARDIMIKNPIAVNSTRTVTQGIEIMR
                     TSKVDSLLIIDRAKTLKGIVTVKDMKDIDDKSILLADIMSSEPLHVNEGDNLVEILNV
                     MNRNSVGYIPVISDENKLVGLITRSSLLSVLSEQFLEMEVSVLG"
     gene            8206..9753
                     /locus_tag="KR231_003322"
     CDS             8206..9753
                     /locus_tag="KR231_003322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HBH0005655.1"
                     /translation="MANFFNFILLQKDKIIELLIQHMSLTVTSILIAIIVGVPLGIII
                     SRISSLRKFVLGFVNLVQAVPSMALLGLLVPILGIGSKPAIFMVVVYSLLPIVKNTYI
                     GITSIDPVVLESAKGIGLTRNQTLFKIQFPLALPIIMGGVRISAVTAVGLMTLAAFIG
                     AGGLGYLVFSGVQTVNNNMILAGAIPSCIIALLVDYLFSKIEVAVTPKGLNPKAPKKN
                     YIALKVISVVLVVSMLFVVFSSSFSSKKDTITIGSKDYTEQLILGNVYAELVEKNTNL
                     KVKKNLNLGGSSVAFNAIKSGELDMYVDYTGTLLVNVMKHAPIKDADEAYNVVKDTME
                     KENQLTLLDPLGFNNTYTLAMMPETAEKYGINTISDLTKYGKEFTFSPTLEFENREDG
                     LVGLSRDYGLKFKDVKAMNGSLRYTALDNNESQVIDAFLTDGLIKKFNLKILEDDKNF
                     FVPYYAAPLVREDTLKKYPELEKVMNMLSGKINEETMRELNYQVDELGKSPEEVAHSF
                     LVKEGLV"
     gene            10087..10953
                     /locus_tag="KR231_003323"
     CDS             10087..10953
                     /locus_tag="KR231_003323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation transporter"
                     /protein_id="HBH0005656.1"
                     /translation="MDNYKKVKQVLWIILFANFAVALLKIIIGNQIKSYSMTADGFHS
                     LSDGASNIVGLIGIFFASKPKDKNHPYGHKKFEIITSLFISGMLFVIAIKIILSAVLR
                     IANPVVPAITIESLIALIITLFINIFVCMYEYRIGTKLNSYVLISDSLHTRSDIFVSL
                     GVLVTLVGVKLGFPVIIESIVPIIISAFIIYSAYGIFRPSIGILVDRVAVDEDYIKEI
                     VFEFNEVRDVHNIRSRGSKSSIYIDMHVMVDPFISVEQSHDLTHKIEKQIQEEINENA
                     QVIVHIEPFYSF"
     gene            11094..12236
                     /locus_tag="KR231_003324"
     CDS             11094..12236
                     /locus_tag="KR231_003324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HBH0005657.1"
                     /translation="MRYVEYGKTGKMVSVVGYGGLRFDLEKSNQENADLVKYAYEKGI
                     NYFDTAPGYCDDRSEDIFGLAFRQMIKEGKTDFYVSTKEKPKACDTSEKAIEAVKKSI
                     ERLGVSKINFYHVWNIRKMEHYELAMRPGGQYEGLLKCKEEGLIDHIVFSSHQPGDEV
                     IDILSENKFEGVTMGINILNFPYRLKGAKYAVDNGYGVVAMNPLSGGTIPKYNKELSF
                     LSKDGESTIESALRFNIGISQISISLIGFNKKQDIDDACKIADENRIYSDEDIHDIET
                     RLNKNMNEICTGCGYCKVCPKGINTPAYMLFYNEKQMFKKSDEEMTKLVYGLGHWNYT
                     MNSKAKAKECISCGKCEVECTQHLPIIDRLKEIKKWEEDGANSVKV"
BASE COUNT         4916 a         1298 c         2261 g         4134 t
ORIGIN      
        1 tatataatat tttgtatata acttaacaaa gtatatgcct atgttataat aatttataga
       61 aataaataaa aaatacaata tacataatag tagaaatata gcaaaaaggt gtgatttata
      121 gggaggatta cttatgtttg aatttgaaac gcaactaaaa aggttaaaac atgaagtttt
      181 aacagcagta gcaagactat ctattgaaga aaatttaaca aaagaaaata tagaaaaaat
      241 tccatatgaa ataattaaag gagaaaaggc gagatataga tgttgtgttt ataaagagag
      301 agaagtagtt cttgaaaggg cgcaacttgc attaagttta actccaaata gtaaatatgg
      361 agatataaat ccagattcag ttagtttgga cacagatgag caaattatat atatagttga
      421 agcagcatgt gatagatgtc caataaatga atttacagtt acagagcttt gtagagggtg
      481 tttggctcat agatgtaagg aagcatgtaa atttggggca atttcttata taaatgggag
      541 agcatatata aatcatgatt tatgtaaggc ttgtggaatg tgcaaaagtt catgtcaata
      601 tgatgctata tcagaagttg taagaccttg taaaagcgtt tgtccaacag gagctttgga
      661 ttttaataga aacactatga aagcaatgat acatgaagat aattgtataa attgtggagc
      721 atgtatgtca gcatgtccat ttggagcaat atctgataag agtttgatag cacctgttgc
      781 aaaaaaactt gcaaagaaag aaaatatgta tgcaatagta gctccagcta taacaggtca
      841 aatagatagt aatattacat atggtcagtt aaaaaatgct ataaaatcac tgggatttgt
      901 agatatgata gaagcttctt gtggagcaga tgcagttaca gttcatgaaa gcaatgaact
      961 tattgaaaga ataaaatcag gagataatta catgacaaat tcatgttgtc cgggattttt
     1021 taagtatata gagaagatgt tcccagatga aaaagataga atatcatcta cagtgtctcc
     1081 tatggtagca acaggaagat tagtaaaaaa aatagattct gatgctaaag ttgtatttat
     1141 aggtccatgt acagctaaaa agagtgaggc aacagagaaa agtttaaaag attcagtaga
     1201 ttatgtactt acttttgaag aactaatggc attatttgaa gcatttaata tagatttatc
     1261 aaaatgttca aatgaagata taaatgatgg ttcgattttt ggaaggggat ttggagcatc
     1321 tggtggactt gccaaatcag tacagaacta tattgctgaa aaggggctta gttttgattt
     1381 tgaacctata aaagtatctg gtccaagaca aattaaaaag acaatgacaa tggctaaatt
     1441 gggaagatta gaaggtaatt ttatagaagg aatgatgtgt gaagaaggtt gtattaatgg
     1501 agcaggtaag tttttatcag gtgtaaaagc taaaaatact tttgatagaa aaaatggaca
     1561 atctactaaa aagagtgttt tatctaatga taagattaaa gaatttgaag atgtaaattt
     1621 agaaagataa ttgttttggt acagtcattt ttttatcatg ccacaaatat gcctaaaatt
     1681 tgcccttttt atatgtgtat tttacagagt taaggttgct atactataaa tatgtaataa
     1741 ataaaattta taggagcttt tggatgagga aaatagtatt aaaagatatc ctgtttttag
     1801 ttactacatt atctataata gtaatattat tgcttgtaac aaatataact actaatagta
     1861 agataaaatc aacgaatgaa tcttatttaa aaagtgacaa aaatgatgtg agtcaaaata
     1921 atattcagag tagcacaaaa aatactgcat ttaagactac tatattaagt actggaaagt
     1981 ctgactgtat attggttgaa ataggtaaca aagtcataat gattgataca ggagaagata
     2041 aaaatggaaa acaaatagtg gataggttaa aagaaaaagg aataaataca cttgactatt
     2101 taattttaac tcatttagat aaggaccata taggtggagt agatagtgtg ttatctagtg
     2161 ttaaagtaaa gaatattata caagcaaatt ataagaaaga tagtaagcaa tatgatgaat
     2221 atattgattc acttaaaaaa gctgatatag aaccagtgct actaaaagat aatatgaata
     2281 ttgtaatcaa tagtgcagaa ataaacatac atccggcttc aaaaagcaag tacgagagtt
     2341 caaatgatta ttcaataatc actaatataa gctatggagc acataagttt ttatttgcag
     2401 gagatgcaga ggaagaaaga ttgtcagagt ttataaatgg aaatacttta aaatatgatt
     2461 ttgttaaaat gcctcatcat ggaagatatg acaaattaac tgaaacattt ttagagtcta
     2521 tttcacccca atatgctgtt attacatgtt cagagaaaaa agaaccagag gaaggtgttt
     2581 taaaaatatt ggaaagattg aatataaaaa catttttgac ttctaatgga gaggtagtta
     2641 tcaatagtga tggtaagaca ttgagtgtga atcaataatt tttttaaaaa tatctaaaaa
     2701 aatttaaaaa aatcattagc aaatattacc ccttaaacat agtatatttt aggagctgaa
     2761 actccacata caaaatgact aggaggtaac atattatgtt ggatagattt tttggtgaag
     2821 gcggatttgg tggatgtgct tggtggataa taatattatt cttcttattc ttagcattcc
     2881 aagattgttg ggctgaaatg gacttatgtg catggatacc tttcttaata ttattattaa
     2941 tactttgtga atgtggtgac gtttttgatg gaggatgtgg atgctaaaaa aatcaattta
     3001 gatgatttaa taaagcttat ggtgggtata aataaaatac caaaccaatc acaatctagt
     3061 gtttgaaggt agtcggaaat cccccgctac cttctttttt ttattgttaa aatttatttt
     3121 tgaattattt catttacata taataatttt tacgataaag tctgatataa ttaaaaagaa
     3181 aataaaattt atttatagga gatgtaaaaa tggctatagt ggataagatt ttcaatgaga
     3241 taaaacttat ggttgcaaga cttttattgg gaaaaaaata cagtgaatat gaagaaaaag
     3301 atttagtgta taatacagaa gaagaagtta tacttataac tttaaaaaga ttagtttttc
     3361 agggaaatgt aaacgaagca gaagaaattt tatttgataa agctaagagt gtaaatagtg
     3421 aaaatatgca gtatatagca atagaatttt atactatgct tatggaaaaa actgatgaag
     3481 aattagaagc tatgaatttt tctaaacaag aagtttatca aggtatagaa gatattagaa
     3541 aagtattgaa tttagaataa aagatatatg aaaatattga aataaattaa tgctaaggtg
     3601 agaatattat acttatatat aaaaatatag tattcttatt ttattagtta tattaggtat
     3661 atcttattta ccataaaact atcttgaaaa aaattaatct taattgtata atattacttt
     3721 gagtgaaaaa gtattaacat ttttttataa gatgttttac taaaaaaata tatataaata
     3781 tactgttatc aataagaaat ttaatttagt gaggtgttaa gatgaaagta ggatttgacc
     3841 acaaaaaata tttagaagag cagtctaaat atatcttaga aagagtaaat aattttgaca
     3901 aactttattt agagtttgga ggaaaattga tgggagacct tcatgcaaaa agagtacttc
     3961 caggatttga tgaaaatgca aagataaaag tattacaaca tatgaaagaa aaagttgaag
     4021 ttgtaatttg tgtctatgca ggagatatag aaagaaacaa aataagagga gactttggta
     4081 tcacttatga tatggaagtt ttaagattaa tagatgattt aagaggttat gaactagatg
     4141 taaatagtgt agtaattact agatttgaag gacaacctgc tacaactgta tttataaata
     4201 aattagaacg tagaggaatt aaagtttata agcattatcc aacaaaggga tatccgtcag
     4261 atgttgagac tatagttagt gatgagggat atggagcaaa tgaatatata gaaactacaa
     4321 agccaatagt agtagtcaca gcaccaggac ctaatagtgg aaaacttggt acttgtctaa
     4381 gtcagttgta tcatgaaaat aaaagaggta atgtagttgg atattctaag tttgagacat
     4441 tcccagtttg gaatgtacct gtaaaacatc ctttgaatat agcttatgaa gcagctacag
     4501 ttgatttaaa agatgtgaat atgatagatt cattccacct tgaaacgtat ggtgaaatgt
     4561 cagtaaacta caatagagat ttggaattat ttccagtgct taaaaaaata atagaaaaga
     4621 taactggaaa agaatcaatt ttccaatctc caactgatat gggtgttaat agagttggct
     4681 ttggaataat agatgatgaa gtaataagaa aagcttctat agaagaaata ataagaagat
     4741 actttaaaac tgcctgtgag tataaaaagg gacaagttga taaaggtgct tatgatagaa
     4801 tgaaaatgat tatggaagag cttaacttaa agccagaaga tagaaatgtt gtattacctg
     4861 ctagaaacta cagtaataaa ttgaaagaaa gtgctgacaa gaatgatact tgtcctgtag
     4921 ttgcattaga attagaagat ggtacaatat taactggtaa gggttctgat ttaatgaatg
     4981 gaactgcagc agtagtatta aatgccatta aacatttagc caatatatct gatgatatgc
     5041 acttaatatc acctgtaata ttagaaccta tcataaactt aaaaacaaag actttagcta
     5101 gtagaaatgt ttcacttagt tgccaagagg tgttaactgc acttagtatt tgtgctgtaa
     5161 ctaatccaac tgcacaattt gctatggaaa agttagcatt attaaaaggg tgtcaagctc
     5221 attctactac tatattaaat agagatgatg aacaaacatt tagaaagctt ggtatagatg
     5281 taacttgtga cccagaatat ccttcacaaa atctttacta tagttaaaat tatataaaaa
     5341 aatatgggct gttttaaagt aatagtttga gcagtccatt acaattataa taaaatcagt
     5401 aggctgtctt gcataagaca gtcttttgtt tttaaaacat cccataaatt aaatatatat
     5461 actgttatcc ataaggaatt ttaaatttag ttccttggaa tacctattgt aaagctttta
     5521 tatagttttt gcaagtgttt ttaaggattt tttataaatt atattgaagt taatggatta
     5581 tagatggttt tatttatgga aaatatgaat atataaagaa aataatgaaa aaataccaaa
     5641 aagaaacata agtttggtat aattaaaaag taatataaat aaaattaatc tatttatact
     5701 ttaaaaggtg ataataatga aacattatag aaaaataatt catatagata tggacgcttt
     5761 ttatgcatct atagaacaaa gagataataa aaaattaaaa ggaagacctg ttattgtcgg
     5821 tggaaatcca caaagccgag gtgtggttgc aacgtgttct tatgaagcta gaaaatttgg
     5881 tatccattca gctatgccat cagctgtagc ttacaatagg tgtccatatg cagtttttgt
     5941 aagacctcga tttgatgttt ataagagtgt gtcagagcaa ataagagata tattttatag
     6001 atacacggat ttagttgaac cattatcttt agatgaagct tacttagatg taacaaaaaa
     6061 taaaaaaaat attgattcat caattgagat agcaaagcaa ataaaaaaag atatatttag
     6121 agaagttggt cttacttctt cagctggtgt gtcatacaat aagtttcttg ctaagattgc
     6181 atcagactta agaaagccaa atgggttaac tgtaataacc gaagaaaatg cccaggactt
     6241 tttagataaa ttacctgtga ataaattttt tggtgttgga aaagttactt caaatactct
     6301 taaaaattta ggtataaaaa ctggatatga tttaaggtgt ttaaatttat ttgaacttga
     6361 aaatatattc aaaaaaagag gttatgaatt atataaattt gctagaggaa tagacgatag
     6421 accagtggaa ccaaataggg ttagaaaatc tgttggggct gagactacat taagtcataa
     6481 tttggatatt gatgaagaag aaacacgcaa cattcttgat gaactttgtg aagaagtatg
     6541 tcatagatta aaaaactctg agaagtttgg aaaaacatta acattaaaaa ttaaatatga
     6601 ggactttaca aagataacta gaagccttag tttagaacac tatattgacg aatataatga
     6661 tataagaagt ggtgtagata atttgttgag aaatgttgat gttaatggaa aacaaattag
     6721 gctattggga gttacaatat caaacctaag tgataaaaaa gaaacttata aagatattac
     6781 attatttgaa tacatggata gtatccaaat gtgagttttg tttaaatgaa ataacactag
     6841 ctttaatact atataattga ggctagtgtt attttatgaa tatttttata ttttttgttt
     6901 tttgacatta tgtattatat actatatata aatactttat atttgtagca atattcagac
     6961 aaatagtgac ctaaaaatcg tactttgttt acataaataa aatagtatga tataattata
     7021 aaaacaactt ataatattga agaaggttgc ttgttcgaaa aaggggatga taaattatga
     7081 tagagataag aaatgtaaca aaaaaaatag gaaataatgt tatattagat gatatttctc
     7141 tagttgtaga aacaggtaca ttggtagttt tgattggttc aagtggttgt ggaaagacta
     7201 ctactttgaa gcttataaac aaattaataa aacctacatc tggtgagata tatattaatg
     7261 gcaaaccaat ttctcaggaa aatgaaatag agcttagaag aaaaatagga tatgttatac
     7321 agaacacagg cctattccct catcttacaa taaaagaaaa tatagagcta attccacgcc
     7381 taaaaaagga aaaatccgtt gaagaaattg aaaaaagaac gttgcaacta cttgagatgg
     7441 taggacttga tagtgatgaa tttttgaata agtatccttc agaacttagt ggtggacagc
     7501 aacaaagaat cggtgttgca agagccattg ctactgatgc tgaaataata ttgatggatg
     7561 agccttttag tgctttagac ccaataacga gaacatcttt acaagaacaa ttattttctc
     7621 ttcaagatga attgaaaaaa actataatat ttgtaactca tgatatggat gaggctttaa
     7681 agatagctga taaaatttgt attatgaagg atggaagaat agcacaatat gatactcccg
     7741 aaaatatact tagaaagcct gcaaatgact ttgtaaaaga ttttatcgga gaagatagag
     7801 tttgggataa tccagaatat ataaaagcaa gagatattat gataaaaaat cctattgctg
     7861 ttaattctac tagaactgta actcaaggaa tagaaattat gagaacgagt aaggttgata
     7921 gcttactaat tatagataga gcaaaaacat taaaaggtat tgttactgta aaagatatga
     7981 aagatattga tgataagtca atattacttg ctgatattat gtcaagtgag cctttgcatg
     8041 taaatgaagg tgataattta gtagaaatac taaatgtaat gaatcgtaat tcggttggat
     8101 atattccggt tatttctgat gaaaataaac tggtagggct tattactaga agtagtttac
     8161 tttctgtttt aagtgaacaa ttcttagaaa tggaggtgag tgttcttggc taattttttt
     8221 aactttatac tattacaaaa agataagatt atagagcttt taatacaaca tatgagtcta
     8281 actgttacat ctattttaat agctataata gttggtgttc ctcttggaat aattatttca
     8341 agaatctcat ctcttagaaa gtttgtactt ggatttgtaa acttagtcca agcagttccg
     8401 tctatggcac ttttgggtct tcttgtacct atacttggta taggaagtaa accagccata
     8461 tttatggtag tggtttattc attactacca attgtaaaaa atacgtatat aggtataaca
     8521 agtattgacc cagtagtatt agaatcagct aaaggtattg gtcttacaag aaatcagaca
     8581 ttatttaaaa tacaatttcc tttagcgctt cctataataa tgggtggagt tagaatatct
     8641 gcagttacag ctgttggttt gatgactctt gcagcattta taggtgctgg tggtttggga
     8701 tatttagtat tttcaggggt tcaaactgta aataataata tgattttagc aggggcaatc
     8761 ccatcatgta taattgcact gttagttgat tatttattta gtaaaattga agttgcagtt
     8821 actccaaaag gattaaatcc aaaagcacct aagaagaatt atatagcact taaagtaata
     8881 tctgtagtgc ttgttgtttc aatgttgttc gttgttttta gttctagttt ttcaagtaaa
     8941 aaagatacaa taactattgg ttctaaagat tatacagaac aacttatact tggcaatgtt
     9001 tatgctgaat tagtagaaaa aaatacgaat cttaaagtta agaagaattt aaatctaggt
     9061 ggttcatctg ttgcgtttaa tgcaattaaa tctggtgagt tagacatgta tgttgactat
     9121 acaggtacac ttttggtaaa tgtaatgaaa catgctccga ttaaagatgc tgatgaagca
     9181 tataatgttg taaaagatac tatggaaaaa gaaaatcagt taactttact tgaccctctt
     9241 ggatttaata atacttacac attagctatg atgcctgaaa ctgctgaaaa gtatggaata
     9301 aatactattt ctgatttgac taaatatggt aaagaattta cattctcacc aactttggag
     9361 tttgaaaata gagaagatgg tcttgtaggg ctttctagag attatggttt aaaattcaaa
     9421 gatgtaaaag caatgaatgg aagtttaaga tatacagctt tagataataa tgaatctcag
     9481 gttatagatg catttttaac tgatggtctt attaaaaagt ttaatcttaa gatattagag
     9541 gacgataaaa atttctttgt accatattat gcagcaccat tagtaagaga agatactttg
     9601 aagaaatatc ctgagttaga aaaagttatg aatatgcttt caggaaaaat aaatgaagaa
     9661 actatgagag aacttaacta tcaagtggat gaacttggta aatcaccaga agaagttgct
     9721 cattcattct tagttaaaga aggcttagta taaaaaatta atagtttata tcaaaaattt
     9781 aagggagtgt ctcaaaatga actttttagt tcatgaggca ctctttttta tatgaaatca
     9841 aatatatttt atcatttcaa caataaaaaa gaagattatc tttattttga gacagtctct
     9901 tatttttatg tataccaaaa ccatacctac gatttttatt tataattaag tttcaaatag
     9961 aatgaacaag tacaaccaat tttgaatata aatatagtaa atgtgcttat atacgatttt
    10021 attgtctggt tgattgatat tgatagatag ctttctttat tgaatcgaag ggagggggaa
    10081 tttgttatgg ataactataa gaaagtgaag caagtattgt ggataatttt atttgctaat
    10141 tttgcagtag cattattaaa aatcattatt ggtaatcaaa taaaaagcta tagtatgaca
    10201 gcagacggat ttcattcttt gtcagatgga gcatctaata tagtggggct tataggtatt
    10261 ttctttgcat ctaaaccaaa agataaaaat catccttatg gacataaaaa gtttgaaatt
    10321 ataaccagtt tatttataag tggtatgttg tttgttatag caattaagat aattcttagt
    10381 gcagtgttaa gaatagctaa tccagttgta cctgctataa ctatagaaag tttaattgct
    10441 ttaattatta cactttttat aaatattttt gtatgcatgt atgaatatag aattgggact
    10501 aaactaaata gttatgtttt gatttcggat tcattgcata caagaagtga tatatttgtg
    10561 tctctaggtg tattggttac tttagttggt gttaagttag gatttccagt aataatagaa
    10621 tctatagttc ctattattat ttctgcattc ataatttatt cggcttatgg aatatttagg
    10681 ccatctattg gaattttggt cgatagagtg gctgtagatg aggattatat aaaagaaatt
    10741 gtgtttgaat ttaatgaggt aagggatgtt cacaatatca gaagtagagg tagcaaaagt
    10801 tctatttata ttgacatgca tgtaatggta gacccattta taagcgtaga gcaatctcat
    10861 gatttaacac ataaaattga gaaacaaata caagaagaaa ttaatgaaaa tgctcaagta
    10921 atagtccata ttgaaccttt ttatagtttt taacttagtt ataaaataca agttataaaa
    10981 aaatataatt tataaaaaaa atattatacc ataaataatt tataaaaatt atttatggta
    11041 taatattttc tataaagaaa ttaagtctta atatatctaa ggaggaattt acaatgagat
    11101 acgttgaata tggaaagaca gggaaaatgg tttcagtagt tggctatgga ggattaaggt
    11161 ttgatttaga aaaaagtaat caagaaaatg ctgatttagt caaatatgcg tatgaaaaag
    11221 gtattaatta ctttgataca gcaccagggt attgtgatga cagaagtgaa gatatatttg
    11281 gactagcctt tagacaaatg ataaaggaag gtaagaccga tttttatgta tcaactaaag
    11341 aaaagccaaa agcatgtgat acatcagaaa aagctataga ggctgtaaaa aaatcaatag
    11401 aacgattagg cgtatctaaa ataaattttt atcatgtttg gaatattaga aagatggaac
    11461 attacgaact agcaatgaga cctggaggtc aatatgaagg attattgaaa tgtaaagaag
    11521 aaggattgat agaccatata gtattttcat ctcatcaacc aggagatgag gttatagata
    11581 ttctaagtga aaataagttt gaaggtgtaa ctatgggaat aaatatatta aactttccat
    11641 ataggctaaa aggtgccaaa tatgctgttg ataatggata tggtgttgtg gcaatgaacc
    11701 cattaagtgg tggaactatt ccaaagtata ataaagaact ttcttttcta tcaaaagatg
    11761 gcgaaagtac tatagaatca gctttaagat tcaacatagg aatttcacaa ataagtatat
    11821 ctttgatagg gtttaataaa aaacaagata tagatgatgc atgtaaaatt gcagacgaaa
    11881 atagaattta ttcagatgag gatatacatg atattgagac tagattaaat aagaatatga
    11941 acgaaatatg tacaggttgt ggttattgta aagtatgtcc aaaaggtatt aataccccag
    12001 cctatatgct tttttataat gaaaagcaga tgtttaaaaa gagtgatgaa gaaatgacaa
    12061 agttagttta tggcttagga cattggaatt acacaatgaa tagtaaggca aaagctaaag
    12121 aatgtatatc ttgtggaaaa tgtgaagttg aatgtactca gcatttacct ataatagata
    12181 gattaaaaga aattaaaaaa tgggaagaag atggagctaa tagtgttaaa gtctaattaa
    12241 ttttatacta tatttgaaat ttgtatagta tttagtaatg ttttaaaata tagttttaat
    12301 atttaaggag acagattata attttgtctc cttaaattat gctttaattt gttatagttt
    12361 aattccataa gcaacattgt atatttttat ataaagtttt tcaaatattt tacattaata
    12421 ttgcttacaa attctcattt tatacaacac taatctatgt tatataaaca atacttgact
    12481 gattataaca tcaataaagt aaatattgtg gttgtaaata aagagttatt caattacaat
    12541 aaaacaagta agaacattat gaagatggct attaaatata aggaataaat tgtaggtgtc
    12601 agcaaatcc
//
LOCUS       DAEPHU010000099        12335 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 01A10CD0081
            SAMN05941466-rid12468953.denovo.099, whole genome shotgun sequence.
ACCESSION   DAEPHU010000099 DAEPHU010000000
VERSION     DAEPHU010000099.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941466
            Sequence Read Archive: SRR6291087
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 12335)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12335)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068158.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 22:43:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,892
            CDSs (total)                      :: 3,805
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 87
            rRNAs                             :: 8, 1, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 55
            CDSs (without protein)            :: 55
            Pseudo Genes (ambiguous residues) :: 0 of 55
            Pseudo Genes (frameshifted)       :: 21 of 55
            Pseudo Genes (incomplete)         :: 28 of 55
            Pseudo Genes (internal stop)      :: 16 of 55
            Pseudo Genes (multiple problems)  :: 8 of 55
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12335
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941466-rid12468953.denovo.099"
                     /strain="01A10CD0081"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            <1..780
                     /locus_tag="KR231_003325"
     CDS             <1..780
                     /locus_tag="KR231_003325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HNH endonuclease"
                     /protein_id="HBH0005658.1"
                     /translation="NKLYILERLENYNNKEIVDLENLINNNMLNIEHIMPQTLTNKWK
                     ESLGDNYKEIHDKYLHTIGNLTLTGYNSKLSNKTFEEKKEMEDGFKDSRLYLNKYISS
                     IDKWNEEEIKNRTKILLDRAVEIWKYPSVTYEPPSNSENIFTLEDDDVNFTNESIVSF
                     SILGESYKAKNWTEFYEQVALTLYDLDSVRFNSIVDKTYKRDFIDNIKSRDAYKLRKG
                     IKISENIYLETNLNTEAKLNIIRFLLNEFDIELNEVIFSIK"
     gene            complement(997..1563)
                     /locus_tag="KR231_003326"
     CDS             complement(997..1563)
                     /locus_tag="KR231_003326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HBH0005659.1"
                     /translation="MDTKKVTFSSMCIVINIVLGMVISMINIPLLFLDTIGTVLGAVV
                     LGPFWSALIGGCTNLVLGVISGPTNIPFALVNIVLGLIVGYISKKKGFGYKEAIITGV
                     ILSIVCPLIGTPISVLLFGGLSGSGADLLVGFLVQSGQKIFTAAFFPRILSNIVDKPL
                     SCIMVVYFISKMPKGFIKQYSKNTSSSY"
     gene            1729..2250
                     /locus_tag="KR231_003327"
     CDS             1729..2250
                     /locus_tag="KR231_003327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF523 domain-containing protein"
                     /protein_id="HBH0005660.1"
                     /translation="MKRNREIVVVCHCILNCNSKVEGLSEFKGAQNIAIDLINKGYGI
                     IQLPCPEMIMYGINRWGHVKEQFDNLFFREQCRQMLIPHVRQFDEYLKNDYDIKSIIA
                     IDGSPSCGYNKTCSSKRWFGELSGCNELMDKINDIQMVDGKGIFIEELEKLLKEYNLN
                     IPIVGFDELREDK"
     gene            3049..5127
                     /locus_tag="KR231_003328"
     CDS             3049..5127
                     /locus_tag="KR231_003328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl hydrolase"
                     /protein_id="HBH0005661.1"
                     /translation="MIKISEDYIEKRFDNELLRIEAWGKNSLRIRSFVDQNFVDENYA
                     LNEKPKLNKDDITINKNEDGSAIIKNGKIKAVLDHRDRITFYNDKNEILLKEYIRLRA
                     VKHDDGGEDVGTIEITKDFNSTLKLKSREYRPSYSGEFEVTTRFESEPSEKIFGMGQY
                     QHKFLDLKNTVLELAQRNSQISVPFYISSLGYGLLWNNPGIGKVSFAKNMTEWKMFST
                     NFIDYWITCGESPKELNKNYSQVTGTVPMMPENLLGLWQSKLRYRTSEEVLDVVKEYS
                     KRGIKLSSIAIDYFHWPKQGEYKFDLDYWKNPKELVKKLKEEYSVEPIVSVWPTVQSD
                     AENYNDYLENGYLVNVNRGVRMTMQIQGNTVFVDMTNENAREYVWDRIDKNYKQLGID
                     YYWLDVAEPGYSVYDFDNYRYKKGNVLSCGNIYPIDYLKMIYDGLHNDIESVVTLVRG
                     AWAGAQKYGALVWSGDIDSSFEAFNNQVNTGLNMGLAGIPWWTTDIGGFHGGNPKDPE
                     FRELMVRWFQYATFSPILRMHGDRLPHSKPLSNKGGGSMVTGAPNEIWSYGEEVEVIL
                     TKFIKIRESLKTYLKKLMKEAHEDGTPVMRTLFYEFPEDDKTWEVDNTYMLGDEILVA
                     PIMNYKDRSRKVYLPKGHTWENIFSGVSYEGGKTYEVECPLEEIPIFLKQDSSYNFKE
                     LKNILGEVKS"
     gene            5127..5906
                     /locus_tag="KR231_003329"
     CDS             5127..5906
                     /locus_tag="KR231_003329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBH0005662.1"
                     /translation="MEPQLWQLLLIVLYGFFINYEKNSTMFGTYQPVTAGFITGLILG
                     DINTGLYIGGTLQLLSLGISNFGGASIPDYQTASIVATFITITTKQEASVGISIGIPV
                     ALLMVQLDVLRNTIGIWLVHKAEDGAKKGNYKNITYMQMLGVLLTAATTGIPVALSVI
                     FGPSLINTILKYTPEWLTGGLTVAGGLLPAVGIGLLLRYLPAKEYFSYLVIGFVLAVY
                     MKVPLLGVALIGGAIALIIYKKNLENQEQQYTVVGGMDEDE"
     gene            5899..6708
                     /locus_tag="KR231_003330"
     CDS             5899..6708
                     /locus_tag="KR231_003330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HBH0005663.1"
                     /translation="MSDKVSLNKSNEKVKKSVLWRWFFTSSVSSNYEKMQALAYCYAV
                     LPFLKVVYKDNPEKLQSAVLNHLQFFNTNPWVAPYILGINVAMEELSSEETEEAVASI
                     KTGLMGPVAGLGDSLFVVIPWTIFGAIAANMAIDGSPFGILLWIVVSVALKLLSIPLF
                     NAGYTSGTKLISSIEKSLKILTESTSILGLMVVGALIPSVVKANVALNFQQGDFTMKG
                     QEILDQIMPGLVPAILVVIVYWALKKNIKPIYLILGVMVVSIILYALGILK"
     gene            6728..7210
                     /locus_tag="KR231_003331"
     CDS             6728..7210
                     /locus_tag="KR231_003331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906215.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBH0005664.1"
                     /translation="MEMKGIKNIRIDDRLIHGQVATMWSNKLGVTRLMVVNDAVANNS
                     VQKQVLRMATPAGIASSIITEETAIKNITAGKYEGQNVLLIVKSPVDLIPFVEAGFKI
                     HNINVGNMSSRKDTTVLRPNISVTEEEKEAFKRLLDEGIEITTIMTPDDKKTYLVDIL
                     "
     gene            7231..7635
                     /locus_tag="KR231_003332"
     CDS             7231..7635
                     /locus_tag="KR231_003332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBH0005665.1"
                     /translation="MNSIILMSHGNMAEEVLNSAKMIIGDSIDYPTVNMKQDDGIEGT
                     IEKLKKALEVYKESSEIIIMADLLGGTPCNAALLVANNDSRIKIISGLNLGMVIESAF
                     LDTKELAAKLEKIGKDNISMVEQNASLLSDDE"
     gene            complement(7791..8951)
                     /locus_tag="KR231_003333"
     CDS             complement(7791..8951)
                     /locus_tag="KR231_003333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family transcriptional regulator"
                     /protein_id="HBH0005666.1"
                     /translation="MVTDKYTIREMNERLVLEQIIKNGPISRASIASTIGLNKATISA
                     ITKKLIDESLVHEIGIGNSTHSGGRKPILLVFNKCAGISLSMDIGYDYIFSSLSYLDG
                     TIINSKKLTDIQVSKDNVIQLIDEIINSYNISKIDTPYKVIGLTLAIHGITCENKVLF
                     TPYYNLNEIDLYSILSKKYDFPIHIENEANLTALAENTFSTVHNSLLSLSIHSGFGSG
                     IIINNKLYSGRNGMSGEIGHTIIMPNGKLCPCGNRGCLEQYCSEKKVFEQLSSLENIP
                     KIDSDIVKQLYYEDNHNAKKVIHEFCSYLTIAINNAITTYAPEIIYLNSQIISDIPEI
                     LQITKDMLVSSFNKGINIEISSLGSEASLYGGSAVNIKSFLNIQNLTLINEI"
     gene            9159..10709
                     /gene="xylB"
                     /locus_tag="KR231_003334"
     CDS             9159..10709
                     /gene="xylB"
                     /locus_tag="KR231_003334"
                     /EC_number="2.7.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xylulokinase"
                     /protein_id="HBH0005667.1"
                     /translation="MKLEYVLGVDIGTSGTKTVLFDKLGNTIKSCTYEYPLIQEKSGW
                     AEQDANDWWKAVVESIREVVQSSNISSECIKGIGLSGQMHGLVMLDNEGKTLRNSIIW
                     CDQRTVKECEEITDLVGEERLIEITANPALTGFTASKILWVRNNEPDIYKNTNKILLP
                     KDYIRYKLTGEYATEVSDASGMQLLDIRKRDWSDEVLEKLNIDKNLLGKVYESQEITG
                     YVTRDVASLTGLKEGTIVVGGAGDQAAGAIGNGIVKDGVVSSTIGTSGVVFAYTKEPK
                     IDKEGRVHTFCHAIPNTWHVMGVTQGAGLSLKWFKDNFCQSEVEVSNSLGEDVYEIIN
                     NQVSQVPTGCNGLLYLPYMMGERTPHLDPYARGVFFGLSPIHSKKEIARSIMEGVSYS
                     LKDCMDIIENLNIDVNEVRASGGGGKSKVWRQMQADMFNQDVYTINSSEGPALGVAIL
                     ALVGAGIYENIQKACDAIIKTSTKLEPISENVDTYNIYHRLYKRIYKSLKDDFKLLDE
                     VVNAKINN"
     gene            10805..12142
                     /gene="xylA"
                     /locus_tag="KR231_003335"
     CDS             10805..12142
                     /gene="xylA"
                     /locus_tag="KR231_003335"
                     /EC_number="5.3.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xylose isomerase"
                     /protein_id="HBH0005668.1"
                     /translation="MSEIFKGIGQIKFEGVKSDNELAFRYYNPEQVVGNKTMKEHLRF
                     AMSYWHTLCGEGNDPFGVGTVERPWNNITDPIEIAKIKVDAGFEFMSKMGIEYFCFHD
                     RDIAPEGRDLEETNKILDEIVEYIKVNMEKTGIKLLWGTANMFGNPRFVHGASTTCNA
                     DVYAYAAAQVKKAMEITKYLGGENFVFWGGREGYETLLNTNTELEMDNFARFLQMAVD
                     YAKEIGFTGQFLIEPKPKEPTKHQYDFDTATVLGFLRKYNLDKYFKMNIEANHATLAG
                     HTFQHELNIARINNVLGSIDANQGDLLLGWDTDQFPTNIYDATLAMYEVLKQGGIAPG
                     GFNFDSKVRRASFEVEDLFLAYIAGMDTFAKGLLIAHKLLEDEVFENFTKERYASFSE
                     GIGKDIVEGKVGFKELESYALQMPVIKNKSGRQEMLEAILNRYIYEVDTISNK"
BASE COUNT         4814 a         1380 c         2190 g         3951 t
ORIGIN      
        1 aataagttat atatacttga gaggttagag aattataata ataaagaaat tgttgattta
       61 gaaaatttaa tcaataataa tatgctaaat atagagcata taatgccaca gacattaaca
      121 aataaatgga aggaatcact aggagataac tataaggaga tacatgataa atatttacat
      181 acaattggaa atttaacttt gacaggatat aattcaaaac taagtaataa aacatttgaa
      241 gaaaagaaag aaatggaaga tggatttaaa gatagtaggc tttatctaaa taaatatatt
      301 tcatctatag ataaatggaa tgaagaagaa ataaaaaata gaactaagat attactagat
      361 agagctgtag aaatttggaa atatccaagt gttacatatg aacctccaag taacagtgaa
      421 aatatattta cgttagagga tgatgatgtt aattttacaa atgaaagtat agtatcattt
      481 agtatattag gagagtcata taaggctaaa aattggacag aattttatga acaagttgct
      541 cttactttat atgatttgga ttctgtaagg tttaacagta ttgtagacaa gacttataaa
      601 agagatttta tagataatat taagtctaga gatgcatata aattaagaaa aggtattaaa
      661 atatcagaaa atatatattt agaaacaaat ttaaatacag aggctaaatt aaatataatt
      721 agatttttac ttaatgagtt tgatatagag ttaaatgaag taatattttc cataaaataa
      781 tgaaatatat gtattttttg cgtaatagaa tattaattat attaaaaata aaatagcacc
      841 tcttgatata gatttatagc tcaaatttat atcaagaggt tacgtttaat taaaataata
      901 caaatactat ctaattaaat tattaataaa aatgttatat aaaaatgagt atatagcatt
      961 ttaaagagta ataaatctta cataataaat gatttattaa tatgaactag aagtattttt
     1021 actatattgt tttataaaac ctttaggcat tttacttata aaatatacca ccataataca
     1081 agacaaaggt ttgtctacta tattactaag aatccttgga aagaacgcag cagtaaatat
     1141 cttctgacca gactgaacta aaaaaccaac caataaatca gcaccacttc cacttaaacc
     1201 accaaacaat aaaactgaaa taggagtacc aattaaagga caaacaatag ataaaattac
     1261 tcctgtaata atagcttctt tataaccaaa accttttttc ttagaaatat atccaacaat
     1321 aagaccaaga acaatattta caagggcaaa aggtatattt gtaggacctg atataacacc
     1381 taaaactaag tttgtacacc caccaataag agcactccaa aaaggaccta atacgacagc
     1441 cccaagtaca gtaccaattg tatctaaaaa taataatggt atatttatca tagatataac
     1501 catacctaag acaatattaa taactatgca cattgaagaa aatgtgactt ttttagtatc
     1561 caattataat acctcctaaa aaaatatata catttatcat agtatagatt ataaaagatt
     1621 actaattgta tatttctata tagaatattg gaaatataga acaaataaat aatataatta
     1681 tcaaaatatg tagtatcatt aaaattaaga ataactaagg agattattat gaagagaaat
     1741 agagagattg tagtagtatg tcattgtata ttaaattgta attctaaagt agagggattg
     1801 tcagaattta agggagcaca aaatatagcg atagatttaa taaataaagg gtatggaata
     1861 attcaactac catgcccaga aatgattatg tatggaataa ataggtgggg acatgtaaaa
     1921 gaacagtttg acaatttgtt ttttagagaa caatgtaggc aaatgttaat acctcatgta
     1981 aggcagtttg atgaatattt aaaaaatgat tatgatataa aaagtatcat tgcaatagat
     2041 ggcagtccaa gttgtggtta taataagaca tgtagttcta aacgttggtt tggtgagtta
     2101 agtggttgca atgaattgat ggataaaata aatgatatac aaatggtgga tgggaaaggt
     2161 atttttatag aagagctaga aaagctactt aaagaatata atttaaatat acctatagtt
     2221 ggatttgacg agcttagaga agataagtag agatataaat atttattgtc tcattatgaa
     2281 acaccattat atttggcaga aaaatatgac tgatggacag tacctgaatc atttttaagt
     2341 ggagtaatta gtacttataa agatgtatcc actagttgaa agaaaatgta gagaggtaat
     2401 aaatgaatta agaagtagat aatatatata aaggagtgtc taaaagtgaa ctttttagtt
     2461 tatgagacac tcttttttta tattaaatca agtatattaa atcaaatata ttttaatcat
     2521 tttagcaatg aaaaataaat ttatctatat tttgagacaa catctttttt agttttattt
     2581 atttgttgtc gtttttgact tggtatacaa ttgtatattt tcttaaataa tttaataaat
     2641 tatttataat tataaaatcc attgttttga acaatatcta atatattatt atctgtattt
     2701 ataaggtcac tatacatatt ttcaagtccg atattatcta cataataggc aaatgttatt
     2761 cctgtatgtg ttttaaaaaa actagatgta tataggtatc atcacagata ttaaaagtat
     2821 aaataaaaga tattaagaac gactttccag caatatatta gaaaatttta ctaaaatccg
     2881 gaaagcgatt gacaaacaaa gtcaaataaa gtatattatt ggtaagttag tttaatgtac
     2941 aaatgaatta tatataaaac ctaatttata aataacgata ctaaacgaca ttatttaact
     3001 taagctacac aaagatagaa tattatacca ttgatttagg aggtagccgt gataaaaata
     3061 tctgaagact atattgaaaa aagatttgac aatgaactat tgcgaataga agcatgggga
     3121 aaaaactctt tacgtattag gtcgtttgta gaccaaaatt ttgttgatga aaactatgct
     3181 cttaacgaaa aacctaagtt aaataaagat gatattacaa ttaataaaaa tgaagatgga
     3241 agtgcaatca ttaaaaatgg aaagataaaa gctgtcttag accatagaga tagaattact
     3301 ttttataatg ataaaaatga aatattattg aaagaatata ttcgattaag agctgtaaaa
     3361 catgatgatg gtggagaaga tgtagggaca attgagatta ccaaagactt taactctact
     3421 ctaaagttaa aatcaagaga atatcgacca agctatagtg gagaatttga agtaactact
     3481 agatttgaat ctgagccttc tgaaaagatt tttggaatgg gacaatatca acataaattt
     3541 ttagatttaa agaatactgt tttggagtta gcccaaagaa attctcaaat atcagttcct
     3601 ttttatattt ctagtctagg ttatggactt ttatggaata atccgggaat tggaaaagta
     3661 tcttttgcta aaaatatgac agaatggaag atgttttcta caaattttat agattattgg
     3721 attacttgtg gagaaagccc aaaagagtta aataaaaatt attctcaagt tactggaact
     3781 gttcctatga tgcctgaaaa ccttttagga ctatggcaaa gtaaactaag atatagaact
     3841 tcagaagaag ttttagatgt tgtgaaggaa tattctaaaa gaggaattaa gctttcatca
     3901 attgcaattg actattttca ttggcctaag caaggtgaat ataaatttga cttagattat
     3961 tggaaaaatc ctaaagaatt agttaaaaaa ttgaaagaag agtattcagt agaaccaata
     4021 gtatctgtat ggcctacagt tcaaagtgat gcagaaaact acaatgatta tttagaaaat
     4081 ggctatttag tcaatgttaa tcgtggtgtt agaatgacaa tgcaaattca aggaaataca
     4141 gtctttgtag atatgacaaa tgaaaatgca agagaatatg tttgggatag aatagataaa
     4201 aattataaac aacttgggat tgactattat tggttagatg tagctgaacc tggctattct
     4261 gtgtatgatt ttgataacta tagatataaa aaaggaaatg ttttaagttg tggtaatatt
     4321 tatcctattg attatttaaa aatgatttat gatggtttac ataatgacat agagtctgtt
     4381 gtaactcttg taagaggagc ttgggcagga gctcaaaagt atggagcttt agtatggtct
     4441 ggtgacattg attctagttt tgaagctttt aataatcaag taaatacagg gttaaatatg
     4501 ggactggcag gtataccatg gtggactact gatattggag gtttccatgg aggaaatcct
     4561 aaagacccag aatttagaga acttatggta agatggttcc aatatgctac tttttcacca
     4621 attttgagaa tgcatggaga tagattgcct catagtaaac cattatcaaa taaaggtgga
     4681 ggctcaatgg taactggagc tcctaatgaa atatggtctt atggtgaaga agttgaagta
     4741 attcttacaa aattcataaa aattagagag agcttaaaaa cttatttaaa aaaactgatg
     4801 aaagaagcgc atgaagatgg aacaccagtt atgagaactt tattttatga atttcctgaa
     4861 gatgataaaa cttgggaggt ggataataca tatatgcttg gagatgaaat tttggtagct
     4921 ccaataatga attataaaga tagaagtaga aaagtatatt taccaaaagg acatacatgg
     4981 gaaaatatat ttagtggagt tagttatgaa ggtgggaaaa cttatgaagt tgaatgccca
     5041 ctggaagaaa ttcctatttt cctaaagcaa gattccagtt ataattttaa agaactaaaa
     5101 aatattttgg gagaggtgaa atcataatgg agccacaatt atggcaatta ttattaatcg
     5161 tactatatgg attttttata aactatgaaa aaaattcaac aatgtttgga acatatcaac
     5221 cagtaacagc aggttttatt actggtctta tcttaggaga tataaataca gggttatata
     5281 ttggaggtac attacagcta ttatcattag gtattagtaa ctttggtgga gcatcaatac
     5341 ctgattatca aacagcaagt atagtagcca catttataac tattacgact aagcaagaag
     5401 catctgtagg aatctctata ggtattccag ttgctttatt gatggtacaa ttagatgttc
     5461 ttagaaatac tattggtata tggctagttc ataaagcaga agatggagct aaaaaaggaa
     5521 attataaaaa tataacctat atgcaaatgt taggagtact attaacagca gctacaacag
     5581 gtattccagt tgctctatct gtaatatttg gaccttcttt aattaatacc attttgaaat
     5641 atacacctga atggttaaca ggtggtttaa cagtagctgg aggactactt ccagcagtag
     5701 ggataggatt attacttaga tatcttcctg ctaaggagta ttttagttac ttagtaattg
     5761 gttttgtttt agcagtatat atgaaagtac cattattagg tgtagcttta attggtggag
     5821 caattgcact tataatttac aaaaagaatt tggaaaatca agaacaacaa tatactgtag
     5881 taggaggtat ggacgaagat gagtgataag gtatcattaa ataaatcaaa tgaaaaggtg
     5941 aaaaaaagtg tcttatggcg ctggtttttt actagttctg tttcttcaaa ttatgagaag
     6001 atgcaggcct tggcatactg ttatgcagta ctaccttttt taaaagtagt atacaaagat
     6061 aatccagaaa agttacaaag tgctgtatta aatcatttac aattttttaa cactaatcct
     6121 tgggttgccc cttatatttt gggtattaat gtagcaatgg aggagttatc aagtgaagag
     6181 actgaagagg ctgttgcttc aattaaaaca ggcttgatgg gaccagtagc aggtttagga
     6241 gatagtttat ttgtcgttat tccgtggaca atttttggag ctatagcagc taatatggcg
     6301 atagatggaa gtccatttgg aatcttactg tggattgtag tgagtgtagc attgaaatta
     6361 ttaagtatac cactatttaa tgctggttat acatcaggta ctaagctaat atcttcaatt
     6421 gaaaaaagtt taaagatttt aactgagagt acatctattt taggtttaat ggttgtaggt
     6481 gcattaatac cttcagttgt aaaagctaat gttgctttga actttcaaca aggtgatttt
     6541 acaatgaaag gtcaagaaat attagaccaa attatgcctg ggttagttcc tgcaattcta
     6601 gttgtgattg tttattgggc tcttaaaaag aatataaaac ctatatactt aattttagga
     6661 gtaatggttg tttcaataat tttatatgca ttaggtattt taaaataagg aaaggatgat
     6721 attagatatg gaaatgaaag gtattaaaaa tattcgtata gatgaccgtt taatccatgg
     6781 tcaagttgca actatgtgga gtaataaatt gggtgttaca agattaatgg tagtaaatga
     6841 tgcagtagct aacaattctg ttcaaaaaca agttttaaga atggctacac ctgcaggtat
     6901 agcgtcatct ataattacag aagagactgc tataaaaaat attactgcag gaaagtatga
     6961 aggacaaaat gtattattaa ttgttaagtc tcctgtggac cttattccat ttgtagaggc
     7021 aggatttaaa atacataata taaatgtagg aaatatgtca agtagaaaag atacaacagt
     7081 tctaagacct aatatcagtg ttactgaaga agagaaagaa gcatttaaaa gacttttaga
     7141 tgaaggaatt gaaattacaa ctataatgac gcctgatgat aagaaaactt atcttgtaga
     7201 catcttatag atttaaagag gtgtattaaa ttgaatagta ttattttgat gagtcatggc
     7261 aatatggctg aagaagtctt aaattctgca aaaatgataa taggggattc tatagattat
     7321 cctactgtaa atatgaaaca agatgatgga atagaaggaa caatagaaaa attaaaaaaa
     7381 gctttagaag tgtacaagga aagttcagaa ataattataa tggcagattt actaggtgga
     7441 actccatgca atgctgcttt attagtagcc aataatgaca gtcgaattaa aattatttca
     7501 gggctaaatt taggtatggt tattgaatca gcttttttag atacaaagga attggcagca
     7561 aaattagaga aaataggtaa agataatatt tctatggttg aacaaaatgc aagtttatta
     7621 tctgatgatg agtaggaaga ttatattaat atttaaaacg aagtacttat gttaatactt
     7681 aattgatata caatttttaa aaaatatagc taatcttgca taaactatat aataaatcta
     7741 attttagaat gtataattta aagggttatg gctgtatata gtcataaccc ttatatttca
     7801 ttaattaaag ttaaattttg tatattcaaa aagctcttga tatttacagc agagccacca
     7861 tatagagatg cctcagaccc taatgatgaa atttctatat ttattccttt gttaaaagag
     7921 ctaactaaca tatcttttgt aatctgtaat atctcaggta tatcactaat tatttggcta
     7981 tttaaatata ttatttcagg agcataagtt gtaatagcat tatttatagc tattgttaag
     8041 taactacaaa actcatgaat aacttttttg gcattatggt tatcttcata atatagttgc
     8101 tttactatat cagaatctat tttaggaata ttttctaaag aagaaagctg ttcaaatacc
     8161 tttttttctg aacaatactg ttctaaacag ccacgatttc cacaaggaca tagtttaccg
     8221 ttaggcatga tgatagtgtg accaatttct ccactcatac catttctgcc actatataat
     8281 ttattattta ttataatgcc tgaaccaaat ccactgtgaa tactgagact aagtagtgag
     8341 ttatgtacag ttgaaaaagt attctcagct aaagctgtta agtttgcttc attttctata
     8401 tgaataggaa agtcatactt tttgctaagg atgctatata agtcaatctc attaagattg
     8461 taatatggag taaacaatac tttattttca caagtaatcc catgtatagc caaagtaaga
     8521 ccaattacct tataaggagt gtctattttg gatatgttat aactatttat aatttcatct
     8581 atcaattgta taacattgtc tttacttact tgtatatctg ttaatttctt agaatttata
     8641 atagttccat ctaagtaaga tagagaagaa aatatatagt cgtatccaat gtccatactt
     8701 aaagaaatcc ctgcacattt attaaatact aataatatgg gttttcttcc gccactatga
     8761 gtactatttc caattccgat ttcatgaact agagattcat caataagttt tttggtaata
     8821 gcggatatag ttgctttatt caatcctata gtagaagcta tacttgccct agaaatagga
     8881 ccatttttta taatttgttc aagtaccaat ctttcattca tttctcgaat agtgtattta
     8941 tcagtaacca atttgatatt cctccttaaa ataatattgt aatacttttt acacaaaaat
     9001 aaaaggttat tttgcattga caaagataat taaatatttt attattagtt cataagttag
     9061 tttaatatac taacaaaaat aaagcaagta aaatatacct aaaatataaa aaaattagga
     9121 taggaaaacg atagttatga agtggcattc aaggagggat gaagttggag tatgtattag
     9181 gtgtggatat tggtacatca ggtactaaaa cagttttatt tgataaacta ggaaatacta
     9241 taaaaagttg tacatatgaa tatcctctta tacaagagaa atcaggttgg gcagagcagg
     9301 atgcaaatga ttggtggaaa gctgtagtcg aatctataag agaagtagtt caaagttcaa
     9361 atataagcag tgaatgtata aaaggaattg gattatcagg acagatgcat ggtctagtta
     9421 tgctggacaa tgaaggtaaa acattgagaa actctataat atggtgtgac caacgaacag
     9481 taaaagagtg tgaggagata actgatttag taggtgaaga aagactgatt gaaataactg
     9541 ctaatccagc acttacagga tttacagcat caaagatatt atgggttaga aacaatgaac
     9601 cagatatata taaaaatact aataaaatac ttcttccaaa agattatata agatacaaat
     9661 tgacaggtga atatgctaca gaggtatcag atgcaagtgg tatgcagttg ctcgatataa
     9721 gaaaaagaga ttggagcgat gaagtactag aaaagttaaa tatagataaa aatcttttag
     9781 gtaaagttta tgaatcacaa gagattacag gttatgtgac tagagatgta gcaagtttga
     9841 cagggcttaa agaaggaaca atagtggtag gaggagctgg agaccaagca gcaggagcta
     9901 taggaaatgg aatagttaaa gatggagtag tttcatctac tataggtaca tcaggtgtag
     9961 tatttgctta tacaaaagag ccaaaaattg ataaagaagg tagagttcat actttctgtc
    10021 atgcaatacc aaatacatgg catgttatgg gagttactca aggagctggc ttgtcattaa
    10081 aatggtttaa agataatttc tgtcaaagtg aagtggaagt ttcaaattct ttaggtgaag
    10141 atgtatatga gattataaat aatcaagtaa gtcaagtacc aacaggatgt aatggattgc
    10201 tttacttacc atatatgatg ggagaaagaa ctcctcatct tgacccttat gcaagaggtg
    10261 tgttctttgg attatctcca atccattcta aaaaagaaat tgcaaggtca ataatggaag
    10321 gtgtttcata tagtcttaaa gactgtatgg atataataga gaatcttaat atagacgtta
    10381 atgaagtaag agcctcaggt ggaggtggaa aaagtaaagt atggagacag atgcaagcag
    10441 atatgtttaa tcaagatgta tatactataa attcaagtga aggaccagca cttggagttg
    10501 caattcttgc attagtagga gctggaatat atgaaaatat acaaaaagca tgtgatgcta
    10561 taataaaaac ttcaactaaa ttagaaccaa taagtgaaaa tgtagataca tacaatatat
    10621 atcatagatt gtataaaaga atatacaaat ctttgaaaga tgactttaag ttattagatg
    10681 aagtagttaa tgcaaaaata aataattaaa ttagcttaaa aagaaaaata aagatagaaa
    10741 atagttttaa attaagaaaa catactacat atattatatg tgtaaaatat taggaggaca
    10801 tgaaatgagt gaaatattta aaggaatagg acagataaaa tttgaaggag taaaatctga
    10861 caatgaatta gcatttagat actacaatcc tgaacaagtg gtaggtaata agactatgaa
    10921 agaacactta agatttgcaa tgagctattg gcatacttta tgtggagagg gtaatgaccc
    10981 atttggagta ggcacagtag agagaccttg gaataatata acagacccaa ttgagatagc
    11041 aaagattaaa gttgatgcag gatttgaatt tatgtctaag atgggaattg agtatttctg
    11101 ttttcatgac agagatatag caccagaagg aagagattta gaagagacaa ataagatatt
    11161 agatgaaata gttgagtata taaaagttaa tatggaaaag acaggtataa agttattatg
    11221 gggaactgcc aatatgtttg gaaatccaag atttgttcat ggtgcatcta caacatgtaa
    11281 tgcagatgta tatgcatatg cagcagctca ggttaaaaaa gctatggaaa taactaagta
    11341 cttaggagga gaaaattttg tattctgggg tggaagagaa ggttatgaaa ctttacttaa
    11401 cactaataca gaacttgaaa tggataactt tgcaagattc ttacaaatgg ctgtagatta
    11461 tgctaaggaa ataggattca ctggccaatt cttaatagag cctaagccaa aagagcctac
    11521 taaacatcaa tacgattttg atactgctac tgttttagga tttttaagaa agtataatct
    11581 ggataaatac ttcaaaatga atatagaagc aaaccatgca acacttgcag gacatacttt
    11641 ccaacatgaa ttaaatatag caagaataaa caatgtttta ggtagtatag atgcaaatca
    11701 aggagaccta ttattaggtt gggatacaga ccaatttcca acaaatatat atgatgcaac
    11761 acttgctatg tatgaagtgt taaagcaagg tggaatagca ccaggaggat ttaactttga
    11821 ctctaaagta agaagagcat cttttgaggt agaagactta ttcctagctt atattgcagg
    11881 aatggataca tttgcaaagg gattattaat agctcataaa ttattagaag atgaggtatt
    11941 tgaaaacttt actaaagaaa gatatgcaag ttttagtgaa ggtataggta aggatatagt
    12001 agaaggtaag gttggattta aagagttaga atcttatgca ctgcaaatgc cagttataaa
    12061 gaataagtct ggaagacaag aaatgctaga agctatactt aacagatata tatatgaagt
    12121 agatacaatt tctaataagt aattgtgtag taattaaatt tggatgtttg aataaaataa
    12181 caggatatgt tcttgttttt attctaaaac ggacaaagat aagtatttgt aaaaattctc
    12241 ataatcatga taaattaagg atatagactt aagtataatt agtttatatc cttaaaattt
    12301 ctataaaaaa taatcatttc tatagttatc aatat
//
LOCUS       DAEPHU010000100        12022 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 01A10CD0081
            SAMN05941466-rid12468953.denovo.100, whole genome shotgun sequence.
ACCESSION   DAEPHU010000100 DAEPHU010000000
VERSION     DAEPHU010000100.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941466
            Sequence Read Archive: SRR6291087
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 12022)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12022)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068158.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 22:43:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,892
            CDSs (total)                      :: 3,805
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 87
            rRNAs                             :: 8, 1, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 55
            CDSs (without protein)            :: 55
            Pseudo Genes (ambiguous residues) :: 0 of 55
            Pseudo Genes (frameshifted)       :: 21 of 55
            Pseudo Genes (incomplete)         :: 28 of 55
            Pseudo Genes (internal stop)      :: 16 of 55
            Pseudo Genes (multiple problems)  :: 8 of 55
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12022
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941466-rid12468953.denovo.100"
                     /strain="01A10CD0081"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            <1..574
                     /locus_tag="KR231_003336"
     CDS             <1..574
                     /locus_tag="KR231_003336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0005669.1"
                     /translation="SLFSNSIRTFILGYVLVLVILLVLTISDSSYLNELDMSSYSNGL
                     NLFTILPQIASYMWAFANGISVTIINSTVSMFTLSSSSLFGDTKLMFYAMGALSMLIL
                     LLNGYKLRFKYNTDSIRPIIVFSIYYAFLMGILALFSTFILDSNINFFNTTNYGTTLI
                     MQFKVLQAIVISFVYSFVISLIGYKLNSAD"
     gene            596..1087
                     /locus_tag="KR231_003337"
     CDS             596..1087
                     /locus_tag="KR231_003337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ribbon domain-containing protein"
                     /protein_id="HBH0005670.1"
                     /translation="MEGNTNNKVDDKFSKVKKKFGSGKFKVELYKEKSKLNREIDDIQ
                     EKKAKIFLEMGILTYQKIREDSINDNSFDKFCDELLELDKLIYEKNMEINEMEMAESN
                     VTCECGYVGNVNDKYCAECGKKFELENECDDFIICGYCESEIDTEAEFCPCCGRKIIM
                     DLE"
     gene            1359..2030
                     /locus_tag="KR231_003338"
     CDS             1359..2030
                     /locus_tag="KR231_003338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="HBH0005671.1"
                     /translation="MLDKVKGRLIVSCQALENEPLHSPFIMGRMAKAAMEGGAVGIRA
                     QGVEDIIEIKKVTGLPVIGIIKRNYEDSDIYITPTKKEVDELLTTGCEMIALDATNRV
                     RPNNEDLKELIKYIKENGVLVMADISNYDEAIKAQEYGVDCVSTTLSGYTPYTKTLEG
                     PDFVLMKRLVKDLEIPVIAEGKVNTPQDLKKVFELGVHSSVVGSAITRPQLITEKFVK
                     AIEIN"
     gene            2115..2981
                     /locus_tag="KR231_003339"
     CDS             2115..2981
                     /locus_tag="KR231_003339"
                     /EC_number="4.1.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003452648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylneuraminate lyase"
                     /protein_id="HBH0005672.1"
                     /translation="MKGIYSALLVSFDKEGNINEKGLRQIIRHNIDVCKVDGLYVGGS
                     TGENFMLSTDEKKRIFEIAKDEVKEEIKLIAQVGSVNLKEAVELAKFTTDLGYDAISA
                     VTPFYYKFDFEEIKHYYNTIINSVDNRLIIYSIPFLTGVDMSLDQFGELFENEKIIGV
                     KFTAADFYLLERMRKTFPNKLIFAGFDEMMLPATVLGVDGAIGSTFNVNGVRARQIFE
                     LTKNEKISEALEVQHVTNDLITDILGNGLYQTIKLLLEEQGVEAGYCRQPMKEATDEM
                     KSRAKEIYRKYF"
     gene            3014..4516
                     /locus_tag="KR231_003340"
     CDS             3014..4516
                     /locus_tag="KR231_003340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003462875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:solute symporter"
                     /protein_id="HBH0005673.1"
                     /translation="MVGFTWIDFAILVVYLLAVLFAGLLFSKKEMKGKEFFKGDGTIP
                     WWVTSVSIFATLLSPISFLSLAGNSYGGTWILWFAQLGMFIAIPLTIKFFLPLYSRLE
                     IDTAYEYLEMRYESKGLRVLGALMFIIYQIGRMSIIMYLPSIVLAGLTGIPVNVLIIV
                     MGVIAIIYSYTGGLKAVLWTDFIQGMVLIVGVTGTLFYLIASINGGFGTVMDTLTTGH
                     KFLASNEVMFDKNILSTSAFIIFVGAGLNTFSSYVSSQDIVQRFTTTTDIKQLNKMTY
                     GNGVLSMGLATVFYLIGTCLFIYYTQNPDLAQTVQQDQVFASYIAYELPVGITGILLA
                     AIYAASQSTLSTGLNSVATSWTLDIQTIITKDISMEKQTKIAQYISLGVGILSIAVAI
                     VLANGEIKSAYEWFNSFMGLVLGVLAGIFVLGAFCKKATKMGAYVGFIVSAILVVYLK
                     YRMPEVTSWAYSLITITTSVVVGTIVSAIEAKVKAKVSLPKAETTVYYEK"
     gene            4646..5098
                     /locus_tag="KR231_003341"
     CDS             4646..5098
                     /locus_tag="KR231_003341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhcH/YjgK/YiaL family protein"
                     /protein_id="HBH0005674.1"
                     /translation="MIFGNINHSKTYSTLHEDLLRCFEYAKDNSLIDYEKGTYTIDGD
                     DIFVNIVEYKTCEKEDRFWEAHKKYIDVHLMLDGCERIDINFIENLEQKIYEEKGDFL
                     PLDGKNNGYMELRKGDFLVCYPEDAHMTGIKVLEKENIKKAIFKVLVR"
     gene            5258..6061
                     /locus_tag="KR231_003342"
     CDS             5258..6061
                     /locus_tag="KR231_003342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0005675.1"
                     /translation="MENIDVFLLIGQSNARGLGNPKESIIPNENCFEYLSTDEIINMR
                     CELETSEGDGTIAPAFSNEWNKLTGNKVCFIHNAKDGSRIKNWNHDNNWFLNDTIEKF
                     NTGCTTLSKHYNIENKYVIWIQGESDAKYGSDVLYYKESLKKIAYRLKEECMIDKMFV
                     SLTGYWLGEDEYFIRTRRIAAAQESACSECDILCVGSKIAMQFHDRGLTIDDVHYTQE
                     GLNMLGEDLCKNIYKYHITKEKSVLSDTIDLSEARKYICELEKISKRFV"
     gene            6119..7006
                     /locus_tag="KR231_003343"
     CDS             6119..7006
                     /locus_tag="KR231_003343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HBH0005676.1"
                     /translation="MKNYVCIDVGGTSIKYGFIREDGFIIDKSSLDTEAKEKGGEGIL
                     AKIKDIVKKYIEENEISGICISTAGMVDPVEGKILFALEELIPNYKDMQLKKEVEKEF
                     NIKCEVENDVNCAGLGEMWLGAGRGATSSICLTIGTGIGGCIIINNKLINGFSNSAGE
                     VGYMNVNGSSFQELASTSSLIKKVAKIKNLNENDLNGKIIFDLAKNNDEDCLKELDNM
                     IKSLAVGIANICYVINPEVVILGGGIMAQEKFLKPKIDKALKEVLIERVYKNTNIEFA
                     KRQNDAGMLGALYNFLNKI"
     gene            7025..7873
                     /locus_tag="KR231_003344"
     CDS             7025..7873
                     /locus_tag="KR231_003344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HBH0005677.1"
                     /translation="MSILEQLESPTFKVTKSDKLLIAYIKENIDDVFYKPISQIAKES
                     NIGEATITRFVKKMNFNGLQDFKVTLAQEISTINKKNIINKNIQNDEPALDTAKKLLS
                     SNVTTLENTVEIINSKDVHDCARLIINAKKVYFIGIGYSGIIAQDSNYKFMRIGLNCV
                     SFDSSHTMIMMSSIMEEGDLIIAISHSGETEEIIKTVKLARANNAKIISITENKNSEL
                     KDISDVHLSYVSGETVLETGSISSKLAQFFIIDLVYTQVVKELSNEAIERKIKTTNAI
                     KLFKNE"
     gene            7936..8625
                     /locus_tag="KR231_003345"
     CDS             7936..8625
                     /locus_tag="KR231_003345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HBH0005678.1"
                     /translation="MSKLKDYNIDKVIIFNNLSTKTKNQLKEKVKLKRLQKKEILFYE
                     KDSLDSVYILLEGKVSIFKISENGERKVIFILNSGEVINDITLDASKNSTVGCEAFEN
                     SIVAYYSIEEFLEIMQNDFQLTKDIISYMERRIRRLYRQLKNSISIKVDKKLAAKLYR
                     LSREFGVCCGEWTLLNVNITVTYLADMLGCKRETVSRMIKVLQKEELIKIDNKGFYVK
                     ETELSRYFKNN"
     gene            complement(8955..10145)
                     /locus_tag="KR231_003346"
     CDS             complement(8955..10145)
                     /locus_tag="KR231_003346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009271880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HBH0005679.1"
                     /translation="MSNVKRKDSKNRNLRNGESQRKDGRYVYKYTDIYGKPQFIYAWK
                     LVPTDKTPAGKRDDISLREKEAQIKKDLDDGIDTAGGKMTVCQLYDKKNSQRKNIKRA
                     TEKGRQYLMNALKNDPLGMRAIDTVKQSDAKEWAIRMSERGYAYKTIDNYKRSLKASF
                     YMAIQDDCIRKNPFEFKLSDVLEDDTEPKVILTPEQEERLLAFMETDKIYSKYYDEVV
                     LLLETGLRISEFCGLTTHIDMQNRILNIDHQLLRDSEIGYYIDTPKTKNGKRKIPLTE
                     RAYQALQRILKNRVKAQPLVVGGYSNFLFLNREGLPKVAGNYVGMVRGLIKKYNKYHK
                     DKLPNITPHSFRHTYCTNMANKGMNPNTLQYLMGHANITMTLGYYAHGTFQSAKAELE
                     RLAC"
     gene            complement(10223..10426)
                     /locus_tag="KR231_003347"
     CDS             complement(10223..10426)
                     /locus_tag="KR231_003347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excisionase"
                     /protein_id="HBH0005680.1"
                     /translation="MNNTDVPIWEKYTLTIEEASKYFRIGEKKLRKLAEENIDAGWVI
                     VNGNRIQIKRKQFEKIIDTLDEI"
     gene            complement(10808..11056)
                     /locus_tag="KR231_003348"
     CDS             complement(10808..11056)
                     /locus_tag="KR231_003348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004613734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBH0005681.1"
                     /translation="MKHTFKKPSYYLLSQAMDGDEKAIEKVLAFYDPYISKCCLRPLY
                     DEYGNVYIVVDMELKGLIREALIKMILGFDIALEIEEE"
     gene            complement(11060..11479)
                     /locus_tag="KR231_003349"
     CDS             complement(11060..11479)
                     /locus_tag="KR231_003349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005361151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HBH0005682.1"
                     /translation="MKPSDFQKTVQCRFESCLKKVVRHVVKDYQQGLKRRKEKEISFC
                     ELPEIMVENLAVWDDYETDYTIFNVCGNDIRVYDDELAEALKQLSERNRETLLMYYFL
                     EMNNEEIAKKQNISRSGVFQNRHNSLALMRKLLKEKR"
BASE COUNT         4387 a         1505 c         2175 g         3955 t
ORIGIN      
        1 atctcttttt tcaaattcta taagaacatt catattaggt tatgttttag tattagtaat
       61 actattggta ctaactatat ctgatagtag ttacttaaat gaactagata tgagtagtta
      121 ttcaaatgga ttaaatttat ttactatact cccacaaata gctagttata tgtgggcttt
      181 tgcaaatgga atttcagtaa ccataataaa ctcaacagta tcaatgttta ctttaagttc
      241 ttcatcttta tttggagata ctaaattaat gttttatgca atgggagcat tgtctatgtt
      301 aatattatta ttaaatggat acaagctaag atttaagtat aatacagata gtataagacc
      361 tataatagta tttagtatat attatgcatt tttgatggga atattggcct tatttagtac
      421 atttatacta gatagtaata ttaatttctt taatacaact aattatggaa caactttaat
      481 aatgcaattt aaagtcttac aagctattgt aatttcattt gtatatagtt ttgtgatatc
      541 tttaatagga tataagctaa attcagctga ttaaatatga ttggagggaa tttctgtgga
      601 aggaaatact aataataaag tagatgataa attttctaag gttaagaaaa agtttggtag
      661 tggaaaattt aaagttgaat tatataaaga aaaatcaaaa ttaaatagag agattgatga
      721 tattcaagaa aagaaagcaa agatattctt ggaaatggga atactgacat atcaaaaaat
      781 tagagaagat tctattaatg ataatagttt tgataaattc tgtgatgagt tactagaact
      841 tgataagtta atttatgaaa aaaatatgga aattaatgaa atggaaatgg cagaaagtaa
      901 tgtaacttgt gagtgtggtt atgttggaaa tgtaaatgat aaatattgtg ctgaatgtgg
      961 taaaaaattt gaattggaaa atgaatgtga tgattttata atttgtggtt attgtgaaag
     1021 tgagatagat acagaggctg aattttgtcc atgctgtgga agaaaaatta taatggattt
     1081 agaataatat tgggaaacct atgtatagta tacatgggtt tttttattga aattatttaa
     1141 atggacttat aacagtagtt atataaaatg aaaataaaca ccaaaaaaat gaaataaaat
     1201 ttcttttaaa tgtaaaaaac aagctaatat ataaaataaa tcagtaaaaa tatagatgcg
     1261 agaaaaaata tgaaaaaata ttgcaaagaa aaagttttca tgttattatt aatacataaa
     1321 tcaagaaaat aaatttcaga aacgaggtaa tttaaaaaat gctagataag gtaaagggaa
     1381 gattaatagt atcatgccaa gctttagaaa atgaacctct tcatagtcct tttataatgg
     1441 ggagaatggc taaggctgct atggaaggtg gagctgttgg aattagagct caaggagttg
     1501 aagatattat tgaaataaaa aaagttactg gacttcctgt tataggtatt ataaagagaa
     1561 actatgaaga ttcagatata tatataacgc caactaaaaa agaagttgat gaacttttaa
     1621 caacagggtg tgaaatgata gcattagatg ctaccaatag agttagacca aataatgaag
     1681 acttaaaaga acttataaag tatataaaag aaaacggtgt tctagtaatg gcagatattt
     1741 caaattatga tgaggctatc aaagcacaag agtacggtgt agattgcgtt tcaactacac
     1801 tatctggata tactccatat actaaaacat tagaaggtcc agattttgta ttaatgaaaa
     1861 gattagttaa agatttagaa atacctgtaa tagctgaagg aaaggtaaat actcctcaag
     1921 atttaaaaaa ggtctttgag ttgggtgttc attcatcagt agtaggttca gcaataacaa
     1981 gaccacaatt aataacagaa aaatttgtta aagcaattga aattaattaa aaattaattt
     2041 ataaattaaa aaattattat atttaactat atttgaaaat taaaattgga ggtaaagata
     2101 tgagaacaac agatatgaag ggaatttatt cagcattatt agtttcattt gataaggaag
     2161 gaaatataaa tgaaaaaggg ttaagacaaa taattagaca caatatagat gtttgtaaag
     2221 tagatggtct ttatgtagga ggaagtacag gggaaaactt catgctttca actgatgaaa
     2281 agaaaagaat atttgaaata gctaaagatg aagtgaaaga agaaataaaa ttaatagctc
     2341 aagttggttc agttaattta aaagaagctg tagaacttgc taaatttaca actgatttag
     2401 gatatgatgc aataagtgct gttacacctt tttactataa atttgatttt gaagaaataa
     2461 aacactatta taatacaata ataaattctg tagataatag attaataata tactctatac
     2521 catttttaac tggtgttgat atgagtttag accagtttgg agaattattt gaaaatgaaa
     2581 aaataatagg tgttaagttt acagcagcag atttctactt attagagaga atgagaaaaa
     2641 cattcccaaa taaattaata tttgcaggat ttgatgaaat gatgttacca gctacagttt
     2701 taggtgtaga tggggcaatt ggttctacat tcaatgtaaa cggtgtcaga gctagacaaa
     2761 tattcgaatt aactaagaat gaaaaaatat cagaagcact tgaagtacaa catgtgacta
     2821 atgatttaat aacagatata ttaggaaatg gcttatatca aacaattaaa ttactacttg
     2881 aagaacaagg tgttgaggct ggatactgta gacaacctat gaaagaagca actgatgaaa
     2941 tgaaatcaag agcaaaagaa atatacagaa agtattttta ataaaatact tttagtatgg
     3001 gaggattagt caaatggtag gatttacttg gatagatttt gcaatactag tggtttactt
     3061 attggcagtt ttatttgcag gattgttatt ttcaaaaaag gaaatgaagg gaaaagagtt
     3121 cttcaaaggt gatggaacta ttccgtggtg ggttacatca gtatcaatat ttgccacatt
     3181 attaagtcca atatcatttt tatcattagc aggaaattct tatggtggta cttggatttt
     3241 gtggtttgca caattaggta tgtttatagc aatacctttg acaataaaat ttttcttacc
     3301 tctatatagt aggttagaaa tagatacagc atatgaatac ttagaaatga gatacgaaag
     3361 taaaggtctt agagtacttg gagctttgat gtttataata tatcaaatag gacgtatgtc
     3421 tattataatg tatcttccat caatagttct ggctggtctt acaggaatac ctgtaaatgt
     3481 actgataata gttatgggtg taatagcaat aatttactca tatacaggtg gattaaaggc
     3541 tgtcttgtgg accgatttta tacaaggaat ggtattaata gtaggtgtta cagggacatt
     3601 gttctattta atagcaagta taaatggtgg ttttggaaca gtaatggata ctcttacaac
     3661 tggacacaag ttcttagcaa gtaatgaagt tatgtttgat aaaaatatac tatctacaag
     3721 tgcatttata atatttgttg gagctggtct taatactttt tcatcatatg tatcgagtca
     3781 agatatagtt caaaggttta ctacaacaac tgatataaag caacttaata aaatgacata
     3841 tggaaatggt gttttatcaa tgggacttgc aacagtattt tatctaattg gaacttgttt
     3901 atttatatac tatactcaaa acccagattt agctcaaaca gttcaacaag accaagtatt
     3961 tgcatcatat atagcttatg aattaccagt gggtataaca ggaatactac ttgcagcgat
     4021 atatgcagct tctcaatcaa ctttatcgac agggcttaat tcagttgcta caagttggac
     4081 tttagatata caaactatca taacaaaaga tataagtatg gaaaagcaaa ctaagatagc
     4141 acaatatata tcattaggtg taggtatact ttctatagct gttgcaatag tattagcaaa
     4201 tggagaaata aagtcagcat atgaatggtt caatagtttt atggggctag tactaggtgt
     4261 tttagcagga atatttgtac ttggtgcatt ttgtaaaaaa gcaactaaaa tgggagcata
     4321 tgttggattc atagtatcag caattttagt tgtttattta aaataccgta tgccagaagt
     4381 aacttcttgg gcatattctc taataacaat cacgacttct gtagtggtag gtacaatagt
     4441 tagtgcaata gaagctaaag ttaaagcaaa agtatcttta ccaaaagctg agactactgt
     4501 ttattatgaa aaataatatt taaatgataa attgtcttat agagtgatta gataaataat
     4561 ttagttactc tataagattg tataatatac tttgtataca aaagtataaa aatagatttt
     4621 ataattatat agggagatag tgcttatgat atttggaaat ataaatcata gtaagacata
     4681 ttcaacattg catgaagatt tacttagatg ttttgaatat gctaaagata attcattaat
     4741 agattatgaa aaaggtactt atacaataga tggtgatgat atttttgtga atattgtaga
     4801 gtataaaact tgtgaaaaag aagatagatt ctgggaagct cataagaagt atatagatgt
     4861 tcatttgatg cttgatggat gtgaacgaat agatataaat tttatagaaa atttagaaca
     4921 aaaaatatat gaagaaaagg gcgatttctt gcctcttgat ggtaaaaata atggatacat
     4981 ggaacttaga aaaggtgatt ttttagtttg ttatccggaa gatgctcata tgacaggaat
     5041 aaaagtttta gaaaaagaaa atatcaaaaa agctattttt aaggttttgg ttagataatg
     5101 ataatttata taaccactag ggctgaaaat agtgatttaa ctttcagcga ttagtgagac
     5161 ttcgtaaatt ttagttagat tactattttc agccttagtt ttttatgaga aaattaaaaa
     5221 taattaaaag cttaaaattt tgtaaaggag ttaacttatg gaaaatatag atgtattctt
     5281 attaatagga caaagcaatg ctagaggatt gggaaatcca aaagagagca tcattccaaa
     5341 tgaaaattgt tttgaatatt tgagtactga tgaaattata aatatgagat gtgagctaga
     5401 gacttcagaa ggtgatggta ctatagcacc tgcattttca aatgaatgga ataagcttac
     5461 tggaaataaa gtttgtttta ttcacaatgc aaaagatggt tcaagaataa aaaactggaa
     5521 tcatgataat aactggtttc taaatgacac tatagaaaaa tttaatacag gctgtactac
     5581 cttaagtaaa cattataata tagaaaataa atacgttatt tggattcaag gtgaaagtga
     5641 tgcaaaatat ggtagtgatg tattgtacta taaagaaagt ctaaaaaaaa ttgcgtatag
     5701 gcttaaagaa gaatgtatga ttgataaaat gtttgtaagt ttaactggtt attggcttgg
     5761 agaagatgaa tattttatta gaacaagacg aattgcagca gcacaggagt cggcttgtag
     5821 tgaatgtgat atattatgtg taggaagcaa aattgctatg cagtttcatg acagaggatt
     5881 aactattgat gatgttcatt acactcaaga aggtcttaat atgttaggag aggacttatg
     5941 taaaaatatt tataagtatc atataaccaa agaaaaaagt gtattaagtg atactataga
     6001 cttatcagaa gcaaggaaat atatctgtga attggaaaag ataagtaaaa gatttgtgta
     6061 atataaaatt ttaaatagag ttgttaattt ataaaaataa tttgtatgga gatatgttat
     6121 gaaaaattac gtttgtatag atgttggagg tacttcaata aaatatggtt ttattagaga
     6181 agatggattt ataattgata aatcaagtct tgatactgaa gcaaaggaaa aaggtggaga
     6241 aggaatatta gccaaaataa aagatatagt aaaaaaatat atagaggaaa atgaaataag
     6301 tggtatatgt atatcaactg caggtatggt tgacccagtt gaaggtaaaa tactatttgc
     6361 attagaagaa ttaattccaa actataagga catgcaatta aaaaaagaag tagaaaaaga
     6421 gtttaatata aaatgtgaag ttgaaaatga tgttaattgt gctggacttg gtgaaatgtg
     6481 gcttggagca ggtagaggtg caacatcttc tatatgttta acaataggta ctggaattgg
     6541 tggatgtatt ataataaata ataaactgat aaatgggttt agtaatagtg ctggtgaagt
     6601 aggatatatg aatgtaaatg gaagttcttt tcaagaattg gcatctacta gcagtctaat
     6661 taaaaaagta gcaaaaataa aaaatttgaa tgaaaatgac ttaaatggaa aaataatttt
     6721 tgatttagca aagaataatg atgaagattg tttaaaagaa ctcgataata tgataaaatc
     6781 attagcagtt ggaatcgcaa atatatgtta tgtaataaat ccagaagtgg taattttagg
     6841 tggtgggatt atggcacaag aaaagttcct aaaaccaaaa atagacaaag cattaaagga
     6901 ggttcttata gagagagttt acaaaaacac taatatagaa tttgcaaaga gacaaaatga
     6961 tgcaggaatg cttggagcat tatataattt tttaaacaaa atataaagaa tagaagggtt
     7021 tttaatgagt attttagaac aattggaatc accaactttt aaagtcacaa aatcagataa
     7081 attattaata gcttatataa aagaaaatat agatgatgta ttttataaac caatatcaca
     7141 aatagctaaa gagagcaata ttggtgaagc aactataact aggtttgtaa aaaaaatgaa
     7201 ttttaatgga ttacaggatt ttaaagttac tttagcacaa gaaatatcaa ctatcaataa
     7261 aaaaaatatt ataaataaaa atatacaaaa tgatgagcca gctttggata cagcaaaaaa
     7321 acttttaagt tcaaatgtaa ccactttaga gaacacagta gagataatca atagtaagga
     7381 tgtacatgac tgcgcaaggc ttataataaa tgcaaagaaa gtttacttca taggtattgg
     7441 atattctggt ataatagcac aggattcaaa ctataaattt atgagaatag gtcttaattg
     7501 tgtaagtttt gacagtagtc atacaatgat aatgatgtct tccataatgg aagaaggaga
     7561 tttaataatt gcaatttcac attctggtga aacagaggag attataaaaa ctgtaaagct
     7621 tgcaagagcc aataatgcta aaattatatc aattactgaa aataaaaatt ctgaattaaa
     7681 ggatatttca gatgtacact tatcttatgt atcgggagaa acagtactgg aaaccggttc
     7741 aatatcttct aaattagcac aatttttcat tattgattta gtatatacac aggtagtaaa
     7801 agaactttct aatgaagcta ttgaaaggaa aattaaaact acaaatgcta taaaattgtt
     7861 taaaaatgaa taaaataaga aatttgtaat gttttataga gctctcttaa aaatttagga
     7921 atggagagat attacatgtc taaattaaaa gattataata ttgataaagt aataattttt
     7981 aataatttaa gtactaaaac gaagaatcaa cttaaagaaa aagttaaact aaaaagatta
     8041 caaaaaaaag aaattttatt ttatgaaaaa gatagcttag acagtgttta tatactttta
     8101 gaaggaaagg tatctatttt taagataagt gaaaatggag agagaaaagt aattttcata
     8161 ttaaatagtg gggaagtcat aaatgatatt acacttgacg cttctaaaaa ctctactgtt
     8221 ggctgtgaag catttgaaaa ttcaattgta gcttattata gtattgaaga atttttagaa
     8281 attatgcaaa atgattttca acttacaaag gatattattt cttatatgga aagaagaata
     8341 agacgtttat atagacagtt gaaaaattct atatctataa aagtagataa aaaacttgca
     8401 gcaaaattat ataggttaag tagagaattt ggagtttgct gtggagaatg gactttacta
     8461 aatgtaaata ttacagttac atatttagct gatatgcttg gctgtaaaag ggagactgtt
     8521 tccagaatga taaaggtatt gcaaaaagaa gaacttatta aaattgacaa taaaggtttt
     8581 tatgttaaag aaactgaatt atcaaggtat tttaaaaata attaattatg attaagtaag
     8641 agtattatta gaattttaat taaataaaaa tattattaag agaatctatt tatagattct
     8701 tttttattgt ctaatttatt aatttttatt ttaccctatt gaattgtata aaaaaacaaa
     8761 taagattctt ttttattcaa aaaacttact aaatttttga ttatcttttc ataagttggt
     8821 aaatgccgat atatcccgta tttgagggct ttatcggtat tttctttttg gaagatacct
     8881 tgcataagct ggcatttacc agcatgaaaa tgcaaccaaa agtagtaaat gagtagtaaa
     8941 tatacgttcc gatattaaca agccagtctt tccagttctg cttttgcaga ttggaatgta
     9001 ccgtgtgcgt agtagccaag cgtcatggtt atgttagcgt gtcccatgag atattgcagg
     9061 gtgttcgggt tcattccctt gtttgccata ttcgtacaat aggtatgtcg gaatgaatgt
     9121 ggtgtaatgt ttggtaactt gtctttgtgg tatttgttat acttcttaat cagtcctcgt
     9181 accataccca catagtttcc agcgacttta ggcaatccct cacggtttaa gaataggaaa
     9241 ttgctgtaac caccaacaac cagcggttga gcttttactc tgttctttag tattctttgg
     9301 agtgcttgat aagccctttc cgtcaatgga atttttcgtt ttccgttctt tgtttttgga
     9361 gtgtcaatat agtagccgat ttcgctatct cttaatagct ggtggtctat attgagtatt
     9421 ctgttctgca tatcaatatg cgttgtcagt ccgcaaaatt cagaaatacg aagtcccgtt
     9481 tccagaagaa gcacaacctc atcataatac ttgctgtaaa tcttatccgt ttccataaag
     9541 gcaagcaggc gttcttcctg ctctggcgta agaataactt tcggctcggt atcatcttcc
     9601 agaacatcac ttagcttaaa ttcaaacggg ttctttctga tacagtcgtc ttgtatcgcc
     9661 atataaaatg acgctttcaa ggaacgctta tagttgtcaa tcgttttgta ggcatatcct
     9721 ctttcactca ttctgatagc ccactcttta gcgtccgact gtttgacggt atcaatcgct
     9781 ctcataccca atgggtcatt tttcagagcg ttcataagat actgtcgtcc tttttccgta
     9841 gctcgcttga tgttctttct ttggctgttc ttcttgtcgt aaagctggca gactgtcatt
     9901 ttaccgcctg ccgtgtcaat accgtcatca aggtcttttt ttatctgtgc ttctttttcc
     9961 ctcaacgata tatcatcacg ttttccagca ggcgttttgt ctgtcggtac aagtttccaa
    10021 gcataaataa actgtggctt tccgtatata tcggtatatt tataaacgta tcttccgtct
    10081 tttcgctggc tctctccatt acgcaaattg cgatttttac tgtcttttcg tttcacatta
    10141 gacatagtgt aaagctcctt tccgtcatgg aatgagccgt gatacgctat acttattata
    10201 ccatatccac ggctctatga cattagattt cgtccaatgt atctatgatt ttttcaaatt
    10261 gttttcgctt tatctgaata cggttgccgt tcacgataac ccagccagcg tcaatatttt
    10321 cttcggctaa tttacgcaac ttcttttctc caatgcggaa gtatttggac gcttcttcaa
    10381 tcgtcagtgt atatttttcc cagataggca catcagtatt attcataatt tatgcacccc
    10441 ctttactgtg tgtcagtcta taagttatat aaacaggcag acggctttgg aaagctccat
    10501 tagtatttca actattccca ttcttgtggg cagaaccgca ccatgcggaa gtatcattat
    10561 gctgtaaggg taggtcatgg caaaacgact tttccaacgg tcgctctcgg atcactgcgt
    10621 gggtcgctcg ctttcttttg gaaaggtcat ggcgtacagt tcccgtggct ctctatcctt
    10681 acaaacgtat ctgtctgctt tattcagttt tcaaagagct gtggcgaaag cggtatgctt
    10741 tcatgtaaaa gcaggagcag agcaggaaag aggggattga acaaatcatg ctctgcgtta
    10801 ctgctggtta ttcttcttca atttctaagg caatatcaaa ccctaaaatc attttgataa
    10861 gtgcttctcg gataagtcct tttaactcca tatctacaac gatataaaca ttaccgtatt
    10921 catcatagag tggacgcaaa cagcacttcg atatgtaagg gtcataaaat gcaagtacct
    10981 tttcaatcgc tttttcgtcc ccgtccatag cttgtgaaag caagtagtaa gacggcttct
    11041 taaatgtgtg tttcatttgc tatcgtttct cctttaatag ttttctcata agtgccaatg
    11101 aattgtggcg gttctgaaaa actccgcttc tggaaatgtt ttgctttttg gcgatttctt
    11161 cattgttcat ttccaaaaag taatacatca acaaagtttc tcggttacgt tcggataact
    11221 gtttcaaggc ttctgccaat tcatcatcat agacacgaat atcattaccg catacattga
    11281 aaatcgtata gtctgtttcg tagtcgtccc atacagccaa gttttcaacc atgatttctg
    11341 gaagttcaca aaaggaaatt tctttttctt ttcttcgctt caatccctgc tgatagtcct
    11401 tgacaacatg acggacaact ttcttcaaac agctttcaaa acggcattga acagttttct
    11461 ggaagtcaga cggtttcatc aatctcaccc cctttccgtt atgacgtgaa aagtgtttat
    11521 ccctctttcc gcaccatata gggaatggca agtgtgattt gttaagttga aaccagaaaa
    11581 aatcgaaaaa actttttagt aaaacaaaaa cagcccgtgt gaatgtgaat acacaaacgg
    11641 actgctttat aaatgctatc tgtatgaatt tttaactctt gtagagggta gaatgattgt
    11701 aatactgaac taaaatattt tttcagttgg gaacagcaaa gtattattcc atatacaatc
    11761 atggcgtagc cccctttacc agagctatac cttgtgccac caatgaaaaa ggacggctct
    11821 ggctatatcc aaaaccgccc cgttatgttt tcaagacgca caaaagtata tcatctcgga
    11881 acggttatgg tgatttaaaa tgagaaaaac aaaagaaaca catacttttg atttcagacc
    11941 gctagggctg gcaatcagag aagcccgtga aaaagctggg ctttctcgta atgatttagg
    12001 cgataaggta ttctatgggg aa
//
LOCUS       DAEPHU010000101        11949 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 01A10CD0081
            SAMN05941466-rid12468953.denovo.101, whole genome shotgun sequence.
ACCESSION   DAEPHU010000101 DAEPHU010000000
VERSION     DAEPHU010000101.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941466
            Sequence Read Archive: SRR6291087
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 11949)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11949)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068158.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 22:43:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,892
            CDSs (total)                      :: 3,805
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 87
            rRNAs                             :: 8, 1, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 55
            CDSs (without protein)            :: 55
            Pseudo Genes (ambiguous residues) :: 0 of 55
            Pseudo Genes (frameshifted)       :: 21 of 55
            Pseudo Genes (incomplete)         :: 28 of 55
            Pseudo Genes (internal stop)      :: 16 of 55
            Pseudo Genes (multiple problems)  :: 8 of 55
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11949
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941466-rid12468953.denovo.101"
                     /strain="01A10CD0081"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            149..2059
                     /locus_tag="KR231_003350"
     CDS             149..2059
                     /locus_tag="KR231_003350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease MutS2"
                     /protein_id="HBH0005683.1"
                     /translation="MNSNTFERLQLNEVKELIKIHCVSSLGKNLIDKLTPSGNIGVVR
                     RKLAENKEARKIIENSNHIPLEGLFNAGSTIDKIEKGMIIEPVELVNIEDFLRGCRKM
                     KAFMLEKEFYSPTLSSYALNITECKSIEDEINYCIKSNKVDSNASKELKKIRRNIEIT
                     EGKIKDRLNKFITSTVNKKYIQEFIISKRNDRYVIPIKSSYKNEVNGTILDTSSKGNT
                     VFIEPISVSNLSTELTMLKADETIEEYKILSYLTELIFEKISQIKLNIEILSEYDMVF
                     AKAKYSQKIKGITPKINNNGYIKIIKGKHPLLTGDAVPLDFEIGKNYRSLIITGPNAG
                     GKTVTLKTVGLLTLMVQCGFDISAKEGSEFSVFEKVFVDIGDNQSIENALSTFSSHIK
                     NIAEIMSLSNNSTLVLFDEIGSGTEPNEGAGLAISLLEEFYKMGCITIASTHYGEIKK
                     FATLHPEFENAGMMFDKETLEPLYKLTIGKSEDSNALFISKKMGIKNRVLDRAKEYVI
                     DRNYNLDLVKRSKLQSNIEDKNSSEVILNYTDYNVGDKVKLLDEDDFGIVYKPMDKFN
                     NVEVLFNDNFISVNIKRLQLSIKASELYPEGYDLDVLFTSFKERKLEKDIQRGSKKAL
                     KKIQKEIRENRK"
     gene            complement(2122..2745)
                     /gene="ytaF"
                     /locus_tag="KR231_003351"
     CDS             complement(2122..2745)
                     /gene="ytaF"
                     /locus_tag="KR231_003351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sporulation membrane protein YtaF"
                     /protein_id="HBH0005684.1"
                     /translation="MIESILLVTSLCIDAFVTSFGYGVNKVKVPLYSNIIISVVCSAI
                     LAISLFAGTIVRDFLPQNITMLICFFILFLLGSARLIESFFKSYFKKKSIHSKNYNFN
                     MLDLKLNFNVSIEPDVLDTSKSKVLKSAEAFTLALALSLDGLAIGFGSGLVGVNYIQV
                     ILFSLISNIIAVLLGCLLGNMFVKNVNLNLSWLSGLILLVIGFMKIC"
     gene            2933..3577
                     /locus_tag="KR231_003352"
     CDS             2933..3577
                     /locus_tag="KR231_003352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBH0005685.1"
                     /translation="MEQHSKVGNFGDLLKVLLDEKELSMGELSKKSGIDKSTISRIAN
                     NKQKPNINHLEKMAIHLNINLEELLKASGYEFRNSNNQIFNADSDFSNFDDILGFANL
                     INDKNFNGNIEKELSKCKLYVQTDEGKKLLFDNFNKKIDSIEKQGQFTDRLRQMYADF
                     CTDGLTIKKYLLIGSMLLYFVISTDVIPDFVFPIGFMDDLVALNIVTKLLKNDK"
     gene            3791..4849
                     /locus_tag="KR231_003353"
     CDS             3791..4849
                     /locus_tag="KR231_003353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="potassium channel family protein"
                     /protein_id="HBH0005686.1"
                     /translation="MNCKWISKIDERKKCHREADSSGYCIFHKENKSDEEIQLMMDTL
                     HKEEISEFNGFVFENEFNAEEILTYNYKILDFSESIFKQKANFKKYIFKKNIIFNYTE
                     FRDKVLFNGCVFLENCDFNRTIFSKHYINDRIFEKVKFKGPDLVVNKVENFPRMDGII
                     FSMCTKFVLKNVEYGKSEYEHGKINYRIARNQATKIGEYEMIGFYYYKERIYSSKIMK
                     RSNYPTFSDYLVEKFFDQIARYTTGYGEKPWNILLVIIAIISVFALLYLFVGIESSNS
                     TLVALDINNIGDYSLSEIFKMYMDLWYFSMATFSTVGYGDMVATSLIGKALAGIEVFF
                     GVTIGAIWASVIIKRMIR"
     gene            4953..6137
                     /locus_tag="KR231_003354"
     CDS             4953..6137
                     /locus_tag="KR231_003354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase"
                     /protein_id="HBH0005687.1"
                     /translation="MKNALKKIISLAMILVFIIPNYSYADDKSVDKYSKTSILIDQET
                     GRVLYSKEPDMKVPLASLSKMMTFLLAIEAIENKEVKETDKVKIDKSIASVKGSSYKL
                     KDGEEVPLIELMRGLMIVSGNDAAIAIAKHVCKTKEAFVDRMNKKAKEIGMSNTHFLN
                     PNGLPIYDLSNPKKPAKENISTAKDIAILGKYMFDHYEKQVTAITDMETYTNSDRSFE
                     KSNTNALLRIIPEVDGIKTGYTGNAGYCLSFSMVVNKNDKNEKKRRVIGVVLGTNHKN
                     KRTSASLALLKYGKENFNMKKVIDKDSFIGKKYIKGTKELEVTLKAKDELYTILKDDE
                     SIKSEVKIKNIEYPVKKGDTMGIIKYYTNSGDLLGSVDIVSNNSIDNVSLKTKLKMKF
                     AN"
     gene            6344..7057
                     /gene="rpsB"
                     /locus_tag="KR231_003355"
     CDS             6344..7057
                     /gene="rpsB"
                     /locus_tag="KR231_003355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S2"
                     /protein_id="HBH0005688.1"
                     /translation="MSVISMKQLLEAGVHFGHQTRRWNPKMAKYIFTERNGIYIIDLQ
                     KTVKKVEEAYKFTKEVAETGKPILFVGTKKQAQDAIKDEAERCGMYFVNERWLGGMLT
                     NHKTIKTRINKLRELEKMEEEGVFNVLPKKEVIKLRAEKEKLEKYLGGIKDMPELPGA
                     MFVVDPRKENIAIQEAHRLGIPVVGIVDTNCDPEQLDFAIPGNDDAIRAVKLITGAMA
                     TAVIEGRQGAEEEVAEDQE"
     gene            7136..8047
                     /locus_tag="KR231_003356"
     CDS             7136..8047
                     /locus_tag="KR231_003356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Ts"
                     /protein_id="HBH0005689.1"
                     /translation="MANITAQMVKELRESTGAGMMDCKKALQEAEGNMEKAVDLLREK
                     GLSKAAKKAGRVAAEGLVAIEMNDDNTVASMVEVNSETDFVAKNEDFKVFVKDAACMA
                     LATDKEDIASLLGETHKEGITLQEVLNNRVAKIGEKLDFRRFAKVVTNGQVAGYIHGG
                     GKIGVLVEMETEARDAKVLELGKDVAMQVAAMNPKYVSRDEVDAEYIAHETEVLTQQA
                     LNEGKPANIVEKMVKGRLEKELKEVCLLEQTFVKNPDITVKQLVADVAKAVGSDIKVV
                     KVVRFEVGEGIQKREENFAEEVAKQLK"
     gene            8132..8836
                     /locus_tag="KR231_003357"
     CDS             8132..8836
                     /locus_tag="KR231_003357"
                     /EC_number="2.7.4.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UMP kinase"
                     /protein_id="HBH0005690.1"
                     /translation="MDKPMYKRVLLKLSGEALAGERGFGINNDVVNDIAIAIKKIQEI
                     GVEVAVVVGGGNFWRGRTSEGMDRTTADYIGMLATVMNAMALQDALENIDVATRVQTA
                     IDMRQIAEPYIRRRAVRHLEKERVVIFGAGTGNPYFTTDTTAALRAAEMEAEVILLAK
                     NVDAVYDKDPKVHADAKKFTELSYMEVIQKELKVMDSTATSLCMDNKIPIKVFELTTE
                     NIIRAVKGENIGTTVK"
     gene            8862..9419
                     /gene="frr"
                     /locus_tag="KR231_003358"
     CDS             8862..9419
                     /gene="frr"
                     /locus_tag="KR231_003358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome recycling factor"
                     /protein_id="HBH0005691.1"
                     /translation="MKLEIHKQLEEKMNGTIDALKFEFGTIRAGRANAQMLDKIRVDY
                     YGTPTPINQIGAISVPEPRILMISPWDKSAMHEIEKAIANSDLGLNPSNDGEVIRLSV
                     PALTEERRKELAKKASKAAEEFKVRIRNERRDANEKIKKMEKGGELTEDELKKAQDEV
                     QKMTDKFIKEIDTLLSKKEKDIMEV"
     gene            9422..9625
                     /locus_tag="KR231_003359"
     CDS             9422..9625
                     /locus_tag="KR231_003359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433997.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0005692.1"
                     /translation="MKKYYNLLGLHVDEVKQYFDEQNINYTVKSIEGKKDKEKLVVPR
                     VIKISEIGDSVELIITYFSDSLV"
     gene            9654..10388
                     /locus_tag="KR231_003360"
     CDS             9654..10388
                     /locus_tag="KR231_003360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoprenyl transferase"
                     /protein_id="HBH0005693.1"
                     /translation="MNNNIIYDIDLNNIPTHIAIIMDGNGRWAKARFLPRTAGHKAGV
                     ETIRDIVKECSKLGVKHLTLYAFSTENWKRPKLEVDTLMNLLSTYLRNEIAELHQNNV
                     KVTAIGDISALPKTCIRELNSAKELTKNNTGVNLNLALNYGSRADIKNALIDIVKNCE
                     SGKIDINNIDEDIIKNYLSTKSIPDPDLVIRTSGEQRLSNFLLWEVAYSEFYFTDIHW
                     PDFKKEELQKAIYVYQRRDRRFGGLK"
     gene            10401..11180
                     /locus_tag="KR231_003361"
     CDS             10401..11180
                     /locus_tag="KR231_003361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidate cytidylyltransferase"
                     /protein_id="HBH0005694.1"
                     /translation="MLTRIIASLALVPLFLFVVYGGIPLYIAETAIVYIALHEFYKAF
                     KIKDVHPIFIIGYLFSIYLAVKNIFNLPLEYTYAVIFILFLASIIYMLMGKNNVIDVS
                     ITFLGVFYIGVFLDFIIITINGFEKGSIYVWLIFVISFMTDIFAYFSGYLLGKHKLIP
                     KVSPKKTIEGAIGGIIGSTLCCILFGYLFGIDLLQLAIIGSIGSVIAQLGDLFASSIK
                     RYVGIKDYGKIIPGHGGILDRFDSVILVAPFVYSAIKFFIR"
BASE COUNT         5022 a         1187 c         2074 g         3666 t
ORIGIN      
        1 atgagtccgg agttaaactt cttaataaat aaggagtttg atatataata actccttatt
       61 tattaagttg ttcgcaaaat aactattatc aaagtaaatg atagggtgat ttaaaagacg
      121 ataacttata aataaaggag aaaaaataat gaatagtaat acatttgaaa gattacaact
      181 aaatgaagtt aaagaattaa taaaaataca ttgtgtaagt tcactaggaa aaaatttaat
      241 agataaatta actcctagtg ggaatattgg agtagtaaga aggaaattag cagaaaataa
      301 agaagctaga aagataattg aaaatagtaa tcacatacca cttgaaggat tgtttaatgc
      361 aggttctaca atagataaaa ttgaaaaagg aatgataata gaacctgttg aacttgtaaa
      421 tattgaagat tttttaagag gttgtaggaa gatgaaagct tttatgttag aaaaagaatt
      481 ttattcacct acattaagtt cttatgcctt aaatataaca gaatgtaaaa gtatagaaga
      541 tgagataaat tactgtataa aatctaataa agttgattct aatgctagta aagaattaaa
      601 aaagataaga cgaaatatag aaattacaga aggaaagata aaagatagat taaataaatt
      661 tataacatca actgtaaata aaaagtatat acaagagttt ataataagta aaagaaatga
      721 tagatatgta ataccaatta aatcttctta taaaaatgaa gttaatggta ctatattaga
      781 tacatcatca aaaggaaata cggtatttat tgaacctatt agtgtttcaa atttaagtac
      841 agagttaact atgttaaaag ctgatgaaac tattgaagaa tacaaaatat tatcttattt
      901 aacagaactt atatttgaga agataagtca gataaaatta aatatagaga tactttcaga
      961 atacgatatg gtatttgcaa aagctaagta tagtcaaaaa ataaaaggaa ttactccaaa
     1021 aataaataat aatggctata taaaaataat taaaggtaaa catccacttc taacaggaga
     1081 tgcagtacct ttagattttg aaataggcaa aaattataga agtcttataa taacaggtcc
     1141 taatgcagga ggaaaaactg taacccttaa gactgttggt ttactaactt taatggttca
     1201 atgtggattt gatatttctg caaaagaagg tagtgaattt agtgtatttg aaaaagtttt
     1261 tgtagatata ggggataatc aaagtattga aaatgcctta agtacttttt catcacatat
     1321 aaaaaatatt gcagagatta tgagtttatc aaataattct actcttgttc tgtttgatga
     1381 aataggaagt ggaactgaac ctaatgaagg agctggttta gcaatatcat tattagaaga
     1441 gttttacaaa atgggatgta taactatagc atcaactcat tatggagaga taaaaaagtt
     1501 tgctacattg catccagaat ttgaaaatgc tggtatgatg tttgataaag aaacgttaga
     1561 accattgtat aagttaacta ttggaaaatc tgaagatagt aatgctcttt ttatttctaa
     1621 aaaaatggga ataaaaaata gagttttaga tagagctaaa gaatatgtaa ttgatagaaa
     1681 ctacaattta gatttagtta aaagaagtaa gctacaatct aatattgaag ataaaaatag
     1741 ttctgaagtc attttaaact atacagatta taatgtaggg gataaggtaa aattactaga
     1801 tgaagatgat tttggaattg tatataagcc tatggacaag tttaataatg tagaagtatt
     1861 gtttaatgat aattttattt cagtaaatat aaaaagatta caacttagca taaaagcatc
     1921 agaattgtat ccagaagggt atgatttaga tgtattattt actagtttta aagaaagaaa
     1981 attagaaaaa gatattcaaa gaggttcaaa aaaagctctt aaaaagattc agaaagaaat
     2041 tagagagaat agaaaataaa tataaaaagc acaaaagaaa gcaatctaaa gagaaaagtt
     2101 tatctttaga ttgctttctt attaacatat cttcataaat ccaatgacta acaagattaa
     2161 accacttaac caagataagt ttaaatttac gtttttaaca aacatatttc ctagtaaaca
     2221 accaagtaat actgcaatta tatttgatat taaagaaaat agaataactt gtatataatt
     2281 cacacctaca aggccactac caaaaccgat agctaatcca tctaaactta aagcaagtgc
     2341 aagtgtaaat gcttcagcag atttaagcac tttagattta cttgtatcta agacatcagg
     2401 ttcaatactt acattaaaat ttaatttaag gtctaacata ttaaaattat aattctttga
     2461 gtgtatagat tttttcttaa aataagattt aaaaaaactt tcaattagtc tagcacttcc
     2521 taataaaaat aaaataaaga aacatattaa cattgttata ttttgaggta aaaagtctct
     2581 aactattgta cctgcaaaaa gcgatattgc taaaatagct gaacaaacta cgctgataat
     2641 tatatttgaa tataagggaa ctttaacttt atttacgcca tatccaaagc ttgtcacaaa
     2701 ggcatctata caaagagaag taactaataa aattgattca atcacagtag attaacatcc
     2761 tttctcttaa attttgtact tatattagtt atagtattgt aaaaatggat aaattgttac
     2821 agataatcca ataaattgtt gataaaattc caacatcata caacacctaa ataacaaaag
     2881 aatcatatca tataataata taaaaccaat cataataaag caggtgaaaa taatggaaca
     2941 acatagtaag gttgggaatt tcggtgattt gttgaaagtt ttattagatg aaaaagaatt
     3001 atcaatggga gaactaagta aaaaaagtgg aattgataaa tctactatat ctcgtatagc
     3061 taataataaa caaaagccaa atataaatca tttagaaaag atggcaatac atttaaatat
     3121 taacctagaa gaactgttga aagcttcagg atatgaattt agaaacagca ataatcaaat
     3181 atttaatgca gatagtgatt ttagtaactt tgatgatatt cttggatttg caaatttaat
     3241 caatgataag aactttaatg gaaatattga aaaagagtta agtaagtgta agttatatgt
     3301 ccaaacagat gaaggtaaaa aattactttt tgataatttt aataaaaaaa tagattctat
     3361 tgaaaaacaa ggtcaattta cagatagatt aagacaaatg tatgctgatt tttgtacaga
     3421 tggacttaca ataaagaaat atttattgat tggaagtatg ctactttact ttgttatatc
     3481 aacagatgtg attccagact tcgtgttccc aataggattt atggatgatt tagtagcatt
     3541 aaatatagtt acaaaattac ttaaaaatga taagtaagtt ttagaatcat atttaatata
     3601 taaataaatc aaagtatata aaatttatta ttttttatat gaaacaaatt aaaagcacaa
     3661 tgaagtagat taaaaattta aaactaagaa tctaatatat attttgtaac tatttaagta
     3721 tataaaataa aataatatcc aaactaatac aaaatagtaa taattgtttt gtactggagg
     3781 atatatattt atgaattgta aatggatatc taaaatagat gagagaaaaa aatgtcatag
     3841 agaagcagat tcttctggat attgtatctt tcataaagaa aataagtctg atgaagagat
     3901 acaattgatg atggatactc ttcataaaga agagataagt gaatttaatg gatttgtttt
     3961 tgaaaatgaa tttaatgcgg aagaaatatt aacttacaat tataaaatac tggatttttc
     4021 tgaatccata tttaaacaaa aagcaaattt taaaaaatat atttttaaaa agaatattat
     4081 ttttaactat acagaattta gagataaagt tttatttaat ggttgtgtat tcttagaaaa
     4141 ctgtgatttt aatagaacca tatttagtaa acactatata aatgaccgta tatttgaaaa
     4201 agtgaaattt aaaggacctg atttggtagt taataaagta gaaaattttc cacgaatgga
     4261 tggaataatt tttagcatgt gtacaaaatt tgtgttaaag aatgttgaat atggaaaaag
     4321 tgagtatgag catggcaaga taaattatag aatagctaga aatcaagcaa caaaaattgg
     4381 agaatatgag atgataggat tttactatta taaggaaaga atttatagta gtaaaataat
     4441 gaaacgttct aattatccta ccttcagtga ttatttagtt gaaaaatttt ttgaccaaat
     4501 agcacgttac acaacaggtt atggagaaaa gccatggaat atattattag ttattatagc
     4561 aataataagt gtttttgctt tattatactt atttgtaggc atagaaagtt caaatagcac
     4621 acttgtagct ttagatataa ataatatagg tgattactca ctaagtgaga ttttcaaaat
     4681 gtatatggat ttatggtatt ttagcatggc tacatttagt acagtaggat atggagatat
     4741 ggttgctaca agtttgattg ggaaagcatt ggcaggtata gaagtatttt ttggagttac
     4801 aataggagca atttgggcat ctgtgattat taaaagaatg ataaggtaat atttgtgtaa
     4861 atatggatag gtattaatta ctagatataa attggactaa atagggaaaa tttaaatata
     4921 aatatactta ataatccaag aaggtgaaaa atttgaaaaa tgcactaaaa aaaattatat
     4981 cattagccat gattctagtt tttataatac caaattattc atatgcagat gataaatctg
     5041 tagacaagta ttcaaaaaca tctatactta tagaccaaga aacaggtaga gttttatata
     5101 gtaaagaacc tgatatgaag gtaccattag ctagtttaag taagatgatg acttttttac
     5161 ttgcaataga agctattgaa aataaagaag taaaagaaac tgataaggta aaaatagaca
     5221 aatctattgc atcagtaaaa gggtcaagtt ataaacttaa agatggtgaa gaagtgccac
     5281 ttatagagct tatgagaggt cttatgattg tatcaggaaa tgatgcggca attgctatag
     5341 caaaacatgt ttgtaaaacg aaagaagcat ttgtagatag aatgaataaa aaagcaaaag
     5401 aaataggaat gagtaataca cattttctaa atccaaatgg tcttccaata tacgatttaa
     5461 gcaaccccaa aaaaccagca aaagaaaata tctctactgc aaaagatata gctattcttg
     5521 gaaaatacat gtttgaccat tatgaaaaac aagtaacagc tataactgat atggagacat
     5581 atacaaattc agatagaagt tttgaaaaaa gcaatacaaa tgcattatta agaattatac
     5641 cagaagtaga tggtataaaa actggatata ctggcaatgc tggatattgc ttatcatttt
     5701 ctatggttgt aaataaaaat gataaaaatg agaaaaaacg tagagtaata ggggttgtat
     5761 taggtactaa ccataaaaat aaaagaacct ctgcttcatt agctctactg aaatatggaa
     5821 aagaaaattt caatatgaaa aaagtaattg ataaagatag ctttattggt aagaaatata
     5881 taaaaggaac gaaagagtta gaggttacat taaaagcaaa agatgaactt tatacaatat
     5941 taaaagatga tgaaagtata aagtcagaag ttaagattaa aaatatagag taccctgtta
     6001 aaaaaggtga tactatgggt attataaaat attatactaa ttcaggtgac ttacttggaa
     6061 gtgtagatat agtaagtaat aatagtatag ataacgtatc attaaaaaca aaattaaaaa
     6121 tgaaatttgc aaattaaatt caaaaaatgg tataaaatac acaaaaaaat ataaaaatag
     6181 aaaatatgga aaaaatattg ttatttcttc acctctgtga tatactacta gaggtgaaaa
     6241 aataaaataa atcacacaca gcattgggat ccttaaaagg tgcctattac atggtttttt
     6301 agggagaaga tcaagctgga ggtataaaac caggaggtaa gatatgtcag taatatcaat
     6361 gaaacaatta ttagaagcag gtgttcactt tggtcaccaa acaagaagat ggaaccctaa
     6421 aatggctaag tatatattca cagagagaaa tggaatatat ataatcgact tacaaaaaac
     6481 agttaaaaaa gttgaagaag cttacaagtt cactaaagaa gtagctgaaa caggaaagcc
     6541 aatcttattc gtaggaacta aaaaacaagc tcaagatgcg ataaaagatg aagctgaaag
     6601 atgtggaatg tactttgtta atgaaagatg gttaggtgga atgttaacaa accacaaaac
     6661 tataaaaaca agaataaata aattaagaga attagaaaaa atggaagaag aaggcgtatt
     6721 taatgttctt cctaaaaaag aagttataaa attaagagct gaaaaagaaa aactagaaaa
     6781 atacttaggt ggaataaaag acatgcctga attaccaggt gcaatgttcg tagttgaccc
     6841 aagaaaagaa aacatagcta ttcaagaagc tcatagatta ggtataccag tagttggtat
     6901 agttgatact aactgtgacc cagaacaatt agactttgct ataccaggaa atgatgacgc
     6961 tataagagcc gtaaaattaa taactggtgc tatggcaaca gctgtaattg aaggtagaca
     7021 aggtgctgag gaagaagtag ctgaagacca agaataataa tttgacaatt aaatggtaag
     7081 ggtcgccctt accatttata atatggaata gaataagtag gaggaaactt aaaaaatggc
     7141 taatataact gctcaaatgg taaaagagtt aagagaaagt acaggcgcag gaatgatgga
     7201 ctgcaagaaa gctttacaag aagctgaagg aaacatggaa aaagcagtag atttattaag
     7261 agaaaaagga ttatcaaaag ctgctaaaaa agctggtaga gttgctgctg aaggtctagt
     7321 tgcaatagaa atgaatgatg ataatacagt tgcttctatg gtagaagtta actcagagac
     7381 agatttcgtt gctaaaaacg aagacttcaa agtgttcgtt aaagatgctg cttgtatggc
     7441 attagctact gataaagaag atatagcttc tttattaggt gaaactcata aagaaggaat
     7501 aactttacaa gaagttttaa ataatagagt tgcaaaaata ggtgagaaat tagactttag
     7561 aagatttgct aaagttgtaa ctaatggaca agttgctgga tacattcacg gtggtggaaa
     7621 aataggtgtt cttgttgaaa tggaaacaga agctagagat gctaaagttt tagaattagg
     7681 taaagatgta gctatgcaag ttgctgctat gaatcctaag tatgtttcaa gagatgaagt
     7741 agatgctgaa tacatagcac atgaaacaga agtattaact caacaagctt taaatgaagg
     7801 aaaaccagct aatatagttg aaaaaatggt taaaggaaga ttagaaaaag aattaaaaga
     7861 ggtttgttta ttagagcaaa ctttcgttaa aaatccagat ataactgtta aacaattagt
     7921 tgctgatgtt gctaaggcag taggttctga tataaaagtt gttaaagttg tgagattcga
     7981 agttggtgaa ggtatacaaa agagagaaga aaactttgca gaagaagttg ctaagcaact
     8041 taagtaataa ccaaagagag aacacgcagg tgttctcttt tttaaaaaat agaaaaaatt
     8101 ggatatgaag gattgaaata ggaggtttct gatggataaa ccaatgtaca aaagggtatt
     8161 gttaaaatta agtggagaag cattagcagg agaaagaggt tttggtataa ataatgatgt
     8221 agttaatgat attgctattg ctataaaaaa aatacaagaa ataggtgttg aagtagctgt
     8281 agtagtaggt ggaggaaact tctggagagg cagaaccagt gaaggaatgg acagaactac
     8341 tgctgactat ataggaatgt tagctacagt tatgaatgca atggcgctac aggatgcact
     8401 agaaaatata gatgttgcta caagagttca aactgctata gacatgagac aaattgcaga
     8461 accatatata agaagaagag cagttagaca cttagaaaag gaaagagttg ttatatttgg
     8521 tgcaggaaca ggaaaccctt actttacaac agatacaact gctgctttac gtgctgctga
     8581 gatggaagca gaagttatat tgttagctaa aaatgttgat gcagtatatg acaaggatcc
     8641 aaaagtacat gcagatgcta agaaatttac agaattaagt tacatggaag ttatacagaa
     8701 agaattaaaa gtaatggatt ctacagctac atctttatgt atggataata aaattccaat
     8761 aaaggtattt gagcttacaa cagagaatat aataagagca gtaaaaggcg aaaatatagg
     8821 aactactgta aaataatgaa gaatgaagga ggagtaaaat tatgaaactg gaaatacata
     8881 agcaattaga agagaaaatg aatgggacaa ttgatgcttt aaagtttgaa tttggaacta
     8941 taagagcagg aagagctaat gcacaaatgc tagacaaaat aagagttgat tattatggaa
     9001 ctccaactcc aataaatcaa ataggtgcta tatctgtacc agaaccaaga atattaatga
     9061 tatctccttg ggataaatct gctatgcatg aaatagaaaa agcgatagct aactcagact
     9121 taggattaaa tccatcaaat gatggtgagg ttataagact ttctgtacct gctttaacag
     9181 aagaaagaag aaaagaatta gctaaaaaag ctagtaaagc tgcagaagaa tttaaagtta
     9241 gaataagaaa tgaaagaaga gacgccaatg agaaaattaa aaagatggaa aaaggcggag
     9301 aattaactga agatgaatta aaaaaagcac aagatgaagt tcaaaaaatg actgataaat
     9361 ttataaaaga aatagataca ttattatcta aaaaagaaaa ggacataatg gaggtataat
     9421 attgaaaaaa tattataacc ttttaggtct tcatgtagat gaggtaaaac aatattttga
     9481 tgagcaaaat ataaattata ccgtaaaatc tattgaaggt aaaaaggata aagaaaaact
     9541 tgtagttcct agagttataa aaatatctga gataggtgat agtgtagaac tgataatcac
     9601 atacttttct gactccttag tttaaggagt cagaacaata ttggaggcaa aatatgaata
     9661 acaacattat atatgatata gacttaaata acatacctac tcatattgct attataatgg
     9721 atggaaatgg aagatgggca aaagctagat ttcttccaag aactgcagga cataaggctg
     9781 gagtagaaac tataagagat atagtaaaag aatgctcaaa attaggtgtt aagcacttaa
     9841 cattatatgc attttcaaca gaaaactgga aaagaccgaa acttgaagtt gacacactta
     9901 tgaacttatt atctacatac ttaagaaatg aaatagctga acttcaccaa aacaatgtaa
     9961 aagtaactgc tataggagat ataagtgctt taccaaaaac ttgtataaga gaattaaact
    10021 cagctaagga actgacaaaa aacaatacag gagttaactt aaatttagca ttaaactacg
    10081 gaagtagagc agatataaaa aatgctctta tagatatagt aaaaaattgt gaaagtggta
    10141 aaatagatat aaacaatatt gatgaagata ttataaaaaa ctatttaagc acaaagtcta
    10201 taccagatcc agacttggta ataagaacaa gtggtgaaca aagattgagt aactttttac
    10261 tttgggaagt tgcttattct gagttttact ttactgatat acattggcct gattttaaaa
    10321 aagaagaact acagaaggct atatacgtat atcaaagaag ggatagaaga tttggaggac
    10381 ttaagtaagg agattatttt atgcttacaa gaattattgc ttcactagct ctggttccat
    10441 tatttctatt tgttgtatat ggaggtattc ctctatatat agctgagaca gcaatagttt
    10501 atattgcatt gcatgagttt tataaggcat ttaaaataaa agatgtacat ccaatattca
    10561 ttataggata tttattttct atttatttag ctgtaaaaaa tatttttaat ttaccattag
    10621 aatatactta tgcagtaatt tttattttat ttttagcaag tataatttat atgttgatgg
    10681 gcaaaaacaa tgttatagat gtttcgatta cgtttttagg agttttttat ataggagtat
    10741 ttttagattt tataattata actataaatg gatttgaaaa aggtagtata tatgtatggc
    10801 ttatatttgt gatatctttt atgacagata tatttgcata ttttagtggt tatttacttg
    10861 gaaaacataa gctaattcct aaagttagtc ctaaaaagac tatagaagga gctattggag
    10921 gaataatagg aagtacactt tgttgtattt tatttggata tttatttggc attgatttgc
    10981 ttcaattagc gataatagga agtataggaa gtgtaatagc tcaattagga gatttatttg
    11041 catcttctat aaagagatat gtagggataa aggattatgg aaagataata cctggtcatg
    11101 ggggtatatt agatagattt gatagtgtta tattagttgc accttttgta tatagtgcga
    11161 ttaaattttt tattagataa agattggttg gatttaaaag agcaatctat aattgctagt
    11221 aatgaaaata gctatgtaac ttttaaatgc agagatattc tgcagttatt agttacatgg
    11281 ctattttcat tgttcaaaaa tttagaagac cttggggaat tgtataagaa taggtattac
    11341 tttataatag tatactatat ttgtagtgag tatatttttt atactataac tatcattaaa
    11401 aaatattttt ttgtttaata atttcgatat ttttagctat attatatatt tataatatat
    11461 atgtataaat gtaactaatt tattatccat ttataaattt tatttttaaa tataattaat
    11521 aagaaataag taaattattg gtcttattac acaaaaatag atataattta agtaatatac
    11581 caaaaaaaag gaatatattt acataatatg ataaaataaa ttcaaagagt taaattgtag
    11641 gtaaatagta ttttaattat ttattaaaat atagattatg tatatgccaa atttaaaaag
    11701 agacataaag acattataca aatatattat tggggtgata ttttataaga aaagaagtga
    11761 tgcagtaaat taattgagca atttaaaaat gatttaatga tagtgttgat gaatgtttaa
    11821 aaagaaattt tagaaaaacg tatattgctg tttgtgttgg aggtgatgaa tttgtataat
    11881 ttataggata taaatgatta aactatttaa gataaataca tatcactgta aaatattgat
    11941 aatcatttt
//
LOCUS       DAEPHU010000102        11893 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 01A10CD0081
            SAMN05941466-rid12468953.denovo.102, whole genome shotgun sequence.
ACCESSION   DAEPHU010000102 DAEPHU010000000
VERSION     DAEPHU010000102.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941466
            Sequence Read Archive: SRR6291087
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 11893)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11893)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068158.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 22:43:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,892
            CDSs (total)                      :: 3,805
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 87
            rRNAs                             :: 8, 1, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 55
            CDSs (without protein)            :: 55
            Pseudo Genes (ambiguous residues) :: 0 of 55
            Pseudo Genes (frameshifted)       :: 21 of 55
            Pseudo Genes (incomplete)         :: 28 of 55
            Pseudo Genes (internal stop)      :: 16 of 55
            Pseudo Genes (multiple problems)  :: 8 of 55
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11893
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941466-rid12468953.denovo.102"
                     /strain="01A10CD0081"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            <1..237
                     /locus_tag="KR231_003362"
     CDS             <1..237
                     /locus_tag="KR231_003362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine phosphate synthase"
                     /protein_id="HBH0005695.1"
                     /translation="TLSHIYETKCKEGLNPKGIELLKEAKKITDIKIIALGGILPSNV
                     KETLKYCDDFAIMSTIMRSKDIKKTISNYNEKLN"
     gene            425..1819
                     /gene="yfcC"
                     /locus_tag="KR231_003363"
     CDS             425..1819
                     /gene="yfcC"
                     /locus_tag="KR231_003363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative basic amino acid antiporter YfcC"
                     /protein_id="HBH0005696.1"
                     /translation="MTDSKKKRFIIPHTFTIIFLLIVLMAILTWIVPSGEFSREDVEG
                     RMVVVPGTYQSVESNPQGFADVFKAPIEGFIDSAEVVGFVLIVGGAFGIVNRTGAIEA
                     GIASVISKFKGKELLIIPISMILFGLGGTTFGMAEETLPFYMIFVPLMTSLGYDSLTA
                     IAIVFIGAAAGAAASTINPFSVGIAQALAQLAPGSGVTYRVVIFIAYILISIAFVMYY
                     AKKVKENPESSIVYEIDKNNKSILNQTSTEIKEFTFKEVSVLAIFGIGMAIMIWGVLS
                     QGWYIPEISMCFAAIGVLSGLVGRLSQIEISESFIDGAKDLASAALAIALARGIVIIA
                     QNGFIIDTILNSAAAFLGGLPKVIFVYLSFFLEAALAFLIPSSSGLASLTVPVLAPLG
                     DLVNISAQVIVTAYQFGVGLTNFITPTSGVLMGALAVAHIPFSKWVRFIMPILLILTA
                     VSLVFLTIGIYIGF"
     gene            2336..3703
                     /locus_tag="KR231_003364"
     CDS             2336..3703
                     /locus_tag="KR231_003364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP pyrophosphokinase"
                     /protein_id="HBH0005697.1"
                     /translation="MGLKEFDFIEESIDMLRTMSPTLETISDEIEEYFENILDEKNQE
                     YINVTSRIKSESSLREKIIRNRYLKKYGEASNLIHNVSDLIGLRIECRFIEDENKIYR
                     LLRRYFNKTDDKINYYNKENKNIKLKLSERQPNKQKNGFEIYKIDGVFAYLDREVKFE
                     LQIKSLVNVFWSEIEHKIIYKNNTYLLADKFIKDMMDSIKNNLTMIDNQLLSIYKNFH
                     SGKSFNMKVSKKEIEKLFAKLVYDAFSEKMNKSIGFVVDFKKPCETILNYSFNKQDIS
                     DEVLGNFMLDEFARLNEIVNKDIDFNEQIEFEREPTFDDKFCKDLGNHFRSRLNTEFP
                     WNLFFRILFEIEPYNNTKDFENFVEFIKENVLLEENREQLLCQFEEDSKLIIEDIYDC
                     IFNSISEIDSVEILYNYNLEKINFTSSEIINCICREYECYGEYLEEKEKLMNTFKEKI
                     IQIFE"
     gene            3728..4336
                     /locus_tag="KR231_003365"
     CDS             3728..4336
                     /locus_tag="KR231_003365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdenum cofactor guanylyltransferase"
                     /protein_id="HBH0005698.1"
                     /translation="MRHFSNIYELSKIILEEAICIEKTGVILAGGRNSRMGRDKAFLE
                     LHDKLFIEIAIEAFKNFDELIIISNNEELYSKYDIKVYNDIVKDVGPIGGIYTALEYA
                     KYDIVTIACDMPYLNNQIVERIANKMNDKSVISVTNGKLQPLCSGYKKSIINKVSLCI
                     RENDLKLRSFIDKIDKSYIYFDEEDLFLNVNTVDEYEKLTKV"
     gene            4384..4755
                     /locus_tag="KR231_003366"
     CDS             4384..4755
                     /locus_tag="KR231_003366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA-binding protein"
                     /protein_id="HBH0005699.1"
                     /translation="MNLLKCDSWAVILNNSDKESKAYKILDELKRNMYKVVAIDEEKK
                     PIEGIDVYECLKDVPHNIDVVAIIDKQSKMDVILEEVELLDIQNMWFEKGSFSEMMIK
                     KTKDLKLNIEYNLSLYDELTR"
     gene            4934..5272
                     /locus_tag="KR231_003367"
     CDS             4934..5272
                     /locus_tag="KR231_003367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal-binding domain-containing protein"
                     /protein_id="HBH0005700.1"
                     /translation="MLIVTTEKVEGKKISKVLGLVRGSTIRAKHVGKDIGASFKNLVG
                     GELTGYNEMLTEARQIAIGRMVEDAEAKGANAVIAFRLSSASVMQGAAEMLAYGTAVV
                     LEDDNSILEK"
     gene            5738..6241
                     /locus_tag="KR231_003368"
     CDS             5738..6241
                     /locus_tag="KR231_003368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MogA/MoaB family molybdenum cofactor
                     biosynthesis protein"
                     /protein_id="HBH0005701.1"
                     /translation="MFNVAIITLSDKGYEGKREDITGKKLTEFVENTGAYKVTEYVLI
                     KDDKEMLKENIIRLCNSNKIDLILTNGGTGFSKRDITPEATKEVLEKEIPGLSEYMRM
                     KSTEITKKAILSRGVSGIRNNSIIINLPGSPKGAVENLSFIIDVLDHGIEVLRGEATE
                     CATKKSE"
     gene            6288..7247
                     /gene="moaA"
                     /locus_tag="KR231_003369"
     CDS             6288..7247
                     /gene="moaA"
                     /locus_tag="KR231_003369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP 3',8-cyclase MoaA"
                     /protein_id="HBH0005702.1"
                     /translation="MIDKYGRKIDYLRISLTDKCNLRCVYCMPPDVKFDKNYINENLS
                     FEDYKFIIKAMAEQGITKIRFTGGEPLLYPKLNELIKFTKEECGINNIGMTTNAIGLS
                     DRIFELEKCGLNKVNISLDSLKEYKYKSVTRGGNLKDVLKSIESCLNLGIKVKLNCVA
                     ISGFNDDELKDFMFLTVKSPIDVRFIELMPLGEANRVYKKGYFNVKEMIEKIYGLYKV
                     KNDEKSTAEYYMFKGAKGRIGIITPLSCSFCNTCNRIRLTSSGAIKLCLHSKEEIDIK
                     PFLHKPLLFRESMKDIIKQKPEKHHLIENKCSDTNRRMYEIGG"
     gene            7251..7721
                     /gene="moaC"
                     /locus_tag="KR231_003370"
     CDS             7251..7721
                     /gene="moaC"
                     /locus_tag="KR231_003370"
                     /EC_number="4.6.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cyclic pyranopterin monophosphate synthase MoaC"
                     /protein_id="HBH0005703.1"
                     /translation="MLTHINEKGYAKMVDISEKDDTKRTAVATATITLSKEALEKVKN
                     GQIKKGDVLSVAQVAGIMGAKNTSSNIPMCHQIKLVGCDLEFDVDDSMSAIKIYATCK
                     SLGKTGVEMEALNACSLAALTIYDMCKAVDKKMVISNIHLVEKTGGKSGDFKFE"
     gene            7757..8188
                     /locus_tag="KR231_003371"
     CDS             7757..8188
                     /locus_tag="KR231_003371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MOSC domain-containing protein"
                     /protein_id="HBH0005704.1"
                     /translation="MAKVVSINISEKKGVIKVPVQCAELKINHGIVGDAHAGNWHRQI
                     SLLGKESIDKMKMKGFDQLKYGDFAENVTTEGIEVFSLPVGTKLRIGQCEVEVTQIGK
                     KCHNGCEIKKLTGDCVMPREGIFVKVLKEGIINVNDSIDVI"
     misc_binding    8619..8830
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            8993..10282
                     /locus_tag="KR231_003372"
     CDS             8993..10282
                     /locus_tag="KR231_003372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytosine permease"
                     /protein_id="HBH0005705.1"
                     /translation="MEEEKINYALEQIPENQKRGWVAMFSVLVAIGVDLSSVILGAEL
                     AQSMPMKQAILSVIVGSFFSAILYTTCSLVGSSTSLSTSMITKYVFGEAGAKIFSLVI
                     GVSLLGWFGVQVGFFAQNAQIIIKDIFNLDVSMQILSLIGGLLMMSTAIYGYKAMEKL
                     SVYSVPFLLVLMMLTIFLAFRANGISVDDNMKSTMTFAGGVSLSMSIIIVGAIVSPDI
                     SRWAKSRRDCALSSFLGIQFGNAFMIIVSIVLVKCMGTSDIMRIFITLGIAIPGIIVL
                     TLAQWTTNTSNVYSASLSIALVLKKAPEKVLTIVLGIIATLLAVFGIYEGFIGFLNLL
                     GIVIAPVGGVYTAEYYIVKQELKGFDKGVLYKPIVKRSIVSWIIGILITYLSTYGFIT
                     LTTIAPLDGFIAGFVVQSIIGKVLCSTKNKQEIDKAV"
     gene            10336..11415
                     /locus_tag="KR231_003373"
     CDS             10336..11415
                     /locus_tag="KR231_003373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF917 domain-containing protein"
                     /protein_id="HBH0005706.1"
                     /translation="MRFLTEESVDKIAVGAAVLGTGGGGDPYVGKLVAKQAIKKYGPV
                     KVISLDELDDDALVVPVSGMGSPVITIEKLLSEVELTTPLEIMEKLLNRKVDVIIPIE
                     IGGINSLMPIAVAAKKGLPILDADSMGRAFPEAQMVTFYLEGYEASPAVMSDEKGNSA
                     ILYPVDGIWSERLARTLTVEMGGSSSISDYNLSGAQVKKAAIGNTLTIAETIGGFLLE
                     NKSDSKGAVENILKELRGYKLFEGKVIDIKRELKGGFTRGHAFFAGINEYDGEYSILF
                     QNENLIAKKGDTPLCITPDLIAVLDLETGFPITTERIKYGSRVMVVAFPCNEKWRTEK
                     GIETVGPGYFGYDVEYKTVEELQGK"
     gene            11436..11801
                     /locus_tag="KR231_003374"
                     /pseudo
     CDS             11436..11801
                     /locus_tag="KR231_003374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423610.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
BASE COUNT         4671 a         1132 c         2178 g         3912 t
ORIGIN      
        1 acattatcac atatatatga aactaaatgt aaagaaggat taaatccaaa aggaattgag
       61 cttttaaaag aagctaaaaa gattactgat attaaaataa ttgcacttgg gggaatttta
      121 ccatctaatg tcaaggaaac attaaaatac tgtgatgatt ttgctataat gtcaactata
      181 atgaggtcta aagatattaa aaaaaccata tcaaattata atgaaaagtt gaattagtaa
      241 atatagtata ttgaattttt aacttaaata aaaataaaaa agttatcttt taaattttaa
      301 aaggtagctt ttttatttta tatctttgct aataaaaaat tgtaaaaagg gaaaacttta
      361 gtcagagaga ttaaacaata tcctagaaag atttaaaatt tagtaaagta tggaggacat
      421 tataatgact gacagtaaaa agaaacgatt tattatacca cacactttta caataatatt
      481 tttactaata gtcttgatgg caatattgac ttggatagta ccaagtggtg aatttagtag
      541 agaagatgta gaaggtagaa tggtagttgt accagggact tatcaaagtg tagaaagtaa
      601 tcctcaagga tttgcagatg tttttaaagc accaatagaa ggctttatcg attcagctga
      661 agttgtaggt tttgttttaa tagttggagg tgcttttggt attgtaaata ggactggagc
      721 tatagaagca ggaatagctt cggttatctc taagtttaag ggaaaagaac ttcttataat
      781 tccaatatca atgattttat ttggacttgg aggtacaaca tttgggatgg cagaagagac
      841 attaccattt tatatgatat ttgttccact catgacatcc ttgggatatg attctctaac
      901 agcaatagca attgtattta taggagcagc agcaggagcc gccgcttcaa caataaatcc
      961 attttcagtt ggtattgcac aggcactagc tcaacttgct cctggttcag gagtaactta
     1021 cagagtagtt atttttatag catatatact aataagtata gcatttgtta tgtactatgc
     1081 taagaaggta aaggaaaatc ctgaaagttc aatagtatat gaaatagata aaaataataa
     1141 atcaatactt aatcaaactt caacagaaat aaaagaattt acttttaaag aagtatctgt
     1201 tcttgctata tttggaatag ggatggcaat aatgatttgg ggtgttttaa gtcaaggatg
     1261 gtacattcca gaaatatcaa tgtgttttgc tgcaataggt gtgctttctg gattggttgg
     1321 tagattatct caaattgaaa tctcagaaag ttttatagat ggagcaaaag atttagcatc
     1381 tgcagctctt gctatagctt tggctcgtgg aatcgtaata attgctcaaa atggatttat
     1441 aatagatact atattaaatt ccgcagcagc ctttctaggt gggcttccaa aggttatatt
     1501 tgtatattta tcatttttct tggaagctgc attggcattt ttaattccat catcttcagg
     1561 tcttgcttca cttacagtac ctgtacttgc tcctcttggt gatttggtta atatatcggc
     1621 tcaagtgata gtaaccgctt atcaatttgg tgtgggtctt acaaacttta taactccaac
     1681 ttcaggagta ctgatgggag cacttgcagt agcccatatt ccattttcaa aatgggtaag
     1741 atttataatg cctatcttgt tgattttgac agctgtatct ctagtctttt taacaatagg
     1801 tatttatata gggttttaat taagtgtagt tttatttaag atatttagta atggtataaa
     1861 atgataatat gttttcaata aattgccact aatttaatta gtggtaattt gttttttgta
     1921 tttaaaaata aatatattta cttgtatttt gaattaatat ctacttagac attgttttaa
     1981 ttgttatatt ttcatttaat taagcattga tttatcattt tttatatttc atataacaat
     2041 gcaaaaaata atttttatat agtaaatgac aaaagtttac aataaatgta tattttctta
     2101 ctcattcctt aaaattactc atttagttta ataactctca tttcatatgt aaagttggta
     2161 aaaaaattaa aattaaaagt aaaaaactaa ataaattaat gttaatttga aatatatatg
     2221 aaggtttttg gagaatactt acttatgata ggaaaaaatg ttaaaataat agtgtaatca
     2281 aatataaagg actgaaataa ttaacagtta ttaaatatta ggagtgtaaa aatttatggg
     2341 attaaaagaa tttgatttta ttgaagagtc tattgatatg ttgaggacaa tgtcaccaac
     2401 attagaaact atatcagatg aaatagaaga gtattttgaa aatatcttgg atgaaaagaa
     2461 tcaagaatat ataaatgtaa cctctagaat aaaatcagaa tcaagtttaa gagaaaagat
     2521 aattagaaat agatatttaa aaaaatatgg agaagcaagt aatcttattc ataatgtttc
     2581 tgacttaata ggcctaagaa ttgagtgtag atttattgag gatgaaaaca aaatatatag
     2641 acttttgaga agatatttta ataaaacaga tgacaaaata aactattata ataaagagaa
     2701 taagaatatt aaattaaaac tatctgagag acaacccaat aagcaaaaaa atggatttga
     2761 aatatataaa atagatggag tttttgcgta tttagataga gaagtaaaat ttgaacttca
     2821 aattaaatct cttgtaaatg tgttttggag tgaaatagaa cataaaataa tttataaaaa
     2881 caatacatat ttacttgctg ataaatttat aaaggatatg atggactcta taaagaataa
     2941 tcttactatg atagataatc agcttttaag tatttataaa aactttcatt cagggaagtc
     3001 ttttaatatg aaagtaagta aaaaagaaat tgaaaaatta tttgcgaaac tagtctatga
     3061 cgctttttct gaaaagatga ataaaagtat aggttttgtt gtagatttta aaaaaccatg
     3121 tgagactata ttgaactatt cttttaataa acaagatata agtgatgaag ttttaggtaa
     3181 ttttatgctt gatgagtttg caagattaaa tgaaattgta aacaaggata tagattttaa
     3241 tgagcaaata gaatttgaaa gagaaccaac atttgatgat aagttttgta aagacctagg
     3301 aaatcatttt agaagtagat taaacacaga atttccatgg aacctatttt ttagaatatt
     3361 atttgaaata gagccatata acaataccaa agactttgaa aactttgtag agtttataaa
     3421 agaaaatgtg ctactagaag aaaataggga gcaattatta tgccaatttg aagaagatag
     3481 caaacttata attgaagata tatatgattg tatatttaat agtataagtg agattgatag
     3541 tgttgaaatt ttatataact ataatcttga aaaaataaac tttacatcaa gtgaaatcat
     3601 aaattgtata tgtagagaat atgagtgtta tggtgaatac ttagaagaaa aagaaaagct
     3661 tatgaataca tttaaagaaa agattattca aatctttgag taataggtca atgctgaagt
     3721 ggcgctaatg cgccattttt caaatatata tgaattaagt aaaattattt tggaggaggc
     3781 gatttgtata gagaaaacag gtgtaatttt ggcaggggga agaaattcta gaatgggtag
     3841 agataaagcc tttttagagt tacatgataa gctttttatt gaaattgcaa tagaagcatt
     3901 taaaaacttt gatgagttga taataatatc taataatgaa gaattatatt ctaaatacga
     3961 tattaaagtt tataatgata tagtaaaaga tgttggtcca attggaggaa tatatactgc
     4021 tcttgaatat gcaaagtatg atatagttac aattgcatgt gatatgccat atctaaataa
     4081 tcaaatagtc gaaagaatag ctaataaaat gaatgataaa agtgtgattt cagtgacaaa
     4141 tggaaagtta caaccattgt gttctggata taaaaagagt ataataaata aagtatcttt
     4201 atgtataagg gaaaatgatt taaagctcag aagctttata gataaaatag ataaaagtta
     4261 tatatacttt gatgaagaag atttattttt aaatgtaaac actgttgatg agtatgaaaa
     4321 attaactaaa gtttaattag ctatggttgt aaaatagagt aggatttata tggaggagag
     4381 tttatgaatt tacttaaatg cgattcttgg gcagtaatat taaataatag cgataaagaa
     4441 agtaaagcat ataaaatatt agatgaactt aaaaggaata tgtacaaagt tgttgctata
     4501 gatgaagaga aaaaacctat tgaaggaata gatgtgtatg aatgtttaaa agatgttcca
     4561 cacaatattg atgttgtagc tattattgat aaacaatcta agatggatgt gattttagaa
     4621 gaagtagagc ttttggatat acaaaatatg tggtttgaaa aaggaagctt tagtgaaatg
     4681 atgattaaaa agactaaaga tttaaaatta aatatagaat ataatttaag tttatatgat
     4741 gagttgacta gataaaatta tatatcttaa taataaaaat ataattagtt aataaaacat
     4801 attattttat agtatagatt ggttaataaa agtacagatt ggttaatgaa acattaaatt
     4861 acaatatttg ttaaaaaaat tgtgagttac atgatataat gtattaaata ggatactaag
     4921 gagttgatat attatgttaa tagtaactac agaaaaagta gaaggtaaaa agatatcaaa
     4981 ggttttagga ttagtgagag gaagtacaat aagagcaaaa catgttggaa aagatatagg
     5041 agcaagtttt aagaatcttg ttggaggaga acttactgga tataatgaaa tgctcactga
     5101 agcaagacaa attgccatag gtagaatggt tgaagatgca gaagctaaag gtgcaaacgc
     5161 agtaatagca tttagactgt cttcagcttc agttatgcaa ggggcagcag aaatgcttgc
     5221 ttatggaaca gcagttgttt tagaagatga taatagtatt cttgaaaaat aaaatataaa
     5281 tagttaaaaa gaggcatctt ttaaaaattt tatggatgcc tttttttatt tgaaaaaact
     5341 aatttgagaa gaaattttaa ctattatgac aataaaatta gggtgatatt atataaataa
     5401 gtaaaattat attatataat gtatggtata gactttaaaa attttatttg tagagaaaaa
     5461 tatggacaat gttataataa ttatagaaat taaaagtact tacattcatt atgtatgtga
     5521 catgtataat tagttttata tttaatacag ttttgaagta atatcttcat tttgagaacg
     5581 ttggaataat aaaaaatgta ttattatagg tgatataaat aaaaaataaa tataatatgt
     5641 tatattgctg atagaaaaga gaataaaaga aaataggttt tattaaaaga gatttttatt
     5701 tataggactt aatcaatgta tagaggggtg agaacatatg tttaatgttg caattataac
     5761 acttagtgat aaaggatatg aaggaaaaag agaagatata acaggaaaaa agttaactga
     5821 atttgttgaa aatacaggag cttataaagt tactgaatat gtacttataa aagatgataa
     5881 ggaaatgcta aaggaaaata ttataagact ttgtaatagt aataaaatag atttaattct
     5941 tacaaatgga ggtactggtt tttcaaaaag agatataacc ccagaagcaa ctaaggaagt
     6001 gttggaaaaa gaaataccag gtctgagcga atatatgaga atgaaatcca cagaaattac
     6061 taaaaaggcc atactaagta ggggtgtaag tggaataaga aataattcta taataataaa
     6121 tttacctgga agtcctaaag gtgcagttga aaatctaagt tttataattg atgttttaga
     6181 ccatggcata gaagttttaa gaggagaagc tacagaatgt gccactaaaa aaagtgaata
     6241 gtatataatc tagatagata aaaaatagac aaagaggtag ataaagtatg attgataagt
     6301 atggaagaaa aatagactac cttcgtattt cacttacaga taagtgtaat ttaaggtgtg
     6361 tttattgtat gccaccagat gtaaaatttg ataaaaatta tataaatgaa aatctaagct
     6421 ttgaagacta caagtttatt ataaaggcta tggctgaaca aggtataaca aaaattagat
     6481 ttactggagg agaacctctt ttatatccta aattaaatga gcttataaaa tttacaaaag
     6541 aagaatgtgg aataaataac ataggaatga ccactaatgc tattgggctt tctgatagaa
     6601 tctttgagct tgaaaaatgt ggcttaaata aagttaatat aagtttagat tctttgaagg
     6661 aatataagta taaatccgta acaagaggag gaaacttaaa agatgtctta aaatcgattg
     6721 aatcttgttt aaacttaggt ataaaagtaa agttaaattg cgttgctata agtgggttta
     6781 atgatgatga gcttaaagat tttatgtttt taacagttaa atcaccaatt gatgtaagat
     6841 ttatagagct tatgccatta ggtgaggcta atagagttta taagaagggt tattttaatg
     6901 taaaagaaat gattgaaaaa atatatggtt tatataaagt caaaaatgat gaaaaaagta
     6961 cagcagaata ttatatgttt aaaggagcta aaggaagaat aggaattata actccattaa
     7021 gctgttcatt ttgtaacact tgtaatcgta ttagacttac ttctagtggt gcaataaaat
     7081 tatgtctaca ttcaaaagaa gaaatagata taaaaccatt tttacataaa ccattgttat
     7141 ttagagaatc tatgaaagat ataataaaac aaaaaccaga aaaacatcat ttaatagaaa
     7201 ataaatgtag tgatacaaat aggcgtatgt atgaaattgg aggataagta atgttaacac
     7261 atataaatga aaaagggtat gccaagatgg tggacataag tgaaaaagat gatactaaaa
     7321 gaacggccgt agctacagct acaattactc ttagtaagga agcattagaa aaagtaaaaa
     7381 atggtcagat aaaaaaagga gacgtattgt ctgtagctca agttgcaggt ataatgggag
     7441 ctaaaaatac atcttcaaac ataccaatgt gccatcagat taaattagtt ggatgtgatt
     7501 tagaatttga tgtagatgat tctatgtctg ctattaagat atacgcaacc tgtaaatctc
     7561 ttgggaaaac tggagtagaa atggaagctt taaatgcatg ttctttagca gcacttacaa
     7621 tttatgatat gtgtaaagca gttgataaaa aaatggttat aagtaatatc catcttgtag
     7681 agaagactgg tggaaaatca ggagatttta agttcgagta aattaataat atattgggtt
     7741 aaaatttgga ggaaatatgg cgaaggtagt gtcaataaat ataagtgaga aaaaaggtgt
     7801 aattaaagtt cctgtacaat gtgcagagct aaaaataaat catgggatag ttggagatgc
     7861 acatgcagga aactggcatc gtcagataag cttacttgga aaagaaagca tagataaaat
     7921 gaaaatgaaa ggctttgacc aattaaaata tggagatttt gctgaaaatg taactacaga
     7981 agggatagaa gttttttccc tgcctgttgg tacaaagtta agaatagggc aatgtgaagt
     8041 tgaagtaact caaataggga aaaaatgtca caatggatgc gaaattaaga aattgacagg
     8101 tgactgtgtg atgccacgag aaggaatttt tgtaaaggtt ctaaaagaag gaattataaa
     8161 tgtgaatgat tcaatagatg taatctaatg aagtcactat taaaatataa ttataagtaa
     8221 atactattaa gatttaaata tatattttaa gagagaatta attttaataa aatattttag
     8281 ttataaattg gaatattggt tatataaagc tatgaatgta aaatcatagc tttttgtttt
     8341 tgaattttaa aatataatat tttatttata tatattaaat tatattttat ataaaatcaa
     8401 ttgtttaaat atatattatt tatactgtaa atttatagat aataaagtat aaaaaaaata
     8461 tattttgatg aaatttaaaa aaatacatta tataaatata gtaatagtat gaaaatttac
     8521 atataaaact aaaaaatgca agtaattgac tttttaagtt gacaaaatat tgcatatata
     8581 ttatgatata aatcataaat taactacaaa tcaatattat atattcgtag aagaagaaag
     8641 tagcataaag gaattttaca gagagttaga tttggctgag aactaatatt ggaatttatg
     8701 tgaaaaggac tttggagaat actattgtaa ttatgttaga atagtggttt aattcgcctt
     8761 aagaaaatga gtgagtaaaa ttaattttta ctaataagag tggtaacacg gatttatatt
     8821 cgtctcttgg atttttccaa gaggcgtttt ttattataaa cttatttcag aaaatttaaa
     8881 actatatatt aaatgaaaat tataaaaata tgatagttaa taaatttata aattagaaaa
     8941 ttgtaaaata tgctaaggtc agtagtttta cgatttaaat ggagggatga aaatggaaga
     9001 agaaaaaatt aactatgctc tggaacagat tccagagaat caaaaacgtg gttgggtagc
     9061 tatgttttca gttttagtag caataggtgt ggatttatca tctgttattt taggcgctga
     9121 gttggcacag agtatgccaa tgaaacaagc aatattgtca gtaattgttg gttcattttt
     9181 ttctgcaatt ttgtatacta catgctcttt ggttggctca tctacaagtt tatctacatc
     9241 tatgataaca aagtatgtat ttggagaagc tggagcaaaa atattttctc tagttatagg
     9301 ggtttctcta ttaggttggt ttggagttca agtaggtttc tttgctcaaa atgcacagat
     9361 aataataaaa gatatattta atttagatgt aagtatgcag attttaagcc taataggtgg
     9421 tctcttgatg atgagtactg caatttatgg atataaggca atggagaagt tgagtgtgta
     9481 ttcagtacca tttttattag ttcttatgat gctaactata ttcttagctt ttagagcaaa
     9541 tggaatttca gttgatgata atatgaaatc tactatgaca tttgcaggtg gagtttctct
     9601 gtcaatgagt ataataatag ttggtgcaat tgtatctcct gatataagtc gttgggctaa
     9661 aagtagaaga gactgtgctc tttcaagctt tttgggaata caatttggaa atgcttttat
     9721 gataatagtt tcgatagtat tagtaaaatg tatgggaact tcagatatta tgagaatttt
     9781 tattacatta ggaattgcta taccaggtat aatagtactt acattagcac aatggactac
     9841 aaatacaagt aatgtatatt cagcatcatt aagtatagct cttgtactta agaaggctcc
     9901 tgagaaagta ttaactatag tccttggtat tatagcaaca ttattggctg tatttggaat
     9961 atatgaaggt tttataggat ttttaaattt acttggaatt gtaattgcac ctgttggtgg
    10021 tgtatataca gcagaatatt acatagtaaa gcaagaactt aaaggctttg ataaaggagt
    10081 attatataaa ccaatagtta aacgttcaat agtgtcttgg ataattggta tattaataac
    10141 ttacctttca acatatggat ttataactct tactactata gcacctttag atggttttat
    10201 agcagggttt gtagtacaat ctattattgg aaaagtgctt tgttcaacaa aaaataagca
    10261 agaaatagac aaagcagtat aaagaaattt gtttataaag tataaaataa attagaaata
    10321 tgaggagaaa gtaacatgag atttttaaca gaagaaagtg tagataaaat agcagttggt
    10381 gcagcagtgc ttggaactgg aggtggaggt gacccatatg taggtaaatt ggttgcaaaa
    10441 caagccatta aaaagtatgg tcctgtaaaa gtaataagtt tagatgaact tgatgatgat
    10501 gctttggtag ttccagtatc tggtatgggt tctcctgtaa ttacaataga aaaattactt
    10561 tcagaagttg agttaactac ccctttagaa ataatggaga aattattaaa tagaaaagtg
    10621 gatgttataa ttcctataga aataggaggg ataaactcac ttatgcctat agcagttgct
    10681 gctaaaaaag gacttcctat cttagatgca gattctatgg gtagagcttt ccctgaagct
    10741 caaatggtaa ctttttatct tgaaggatat gaggcatctc ctgccgtaat gtctgatgaa
    10801 aaaggtaatt ctgccatcct ttatcctgtg gatggaattt ggtcagaaag attagctaga
    10861 actttaactg tagaaatggg aggaagttct tctattagtg actataattt aagtggagct
    10921 caagttaaaa aagctgctat aggtaatact cttacaatag ctgaaactat aggagggttt
    10981 ttacttgaaa ataaatctga ttcaaaaggt gctgttgaga atatactaaa agaattgcgt
    11041 ggatacaagt tatttgaagg aaaagtaatt gatattaaga gagagttgaa aggtggattt
    11101 actagaggac atgccttttt tgctgggatt aatgagtatg atggagagta ttctatatta
    11161 ttccaaaatg agaatttaat tgccaaaaaa ggtgatacac cactttgtat tacaccagat
    11221 ttaatagcag tattagattt agaaactgga tttccaataa ctacagagag aataaaatat
    11281 ggctctcgtg ttatggtagt agcttttcct tgtaatgaaa aatggagaac agaaaaagga
    11341 attgagacag ttggacctgg atactttgga tatgatgtgg aatataaaac agtagaagaa
    11401 ttacaaggaa aataaaagtt taggaggaaa ttttgatgta tcgtgtagga attgacgttg
    11461 gaggaacaaa tacagatgct tgtatactgg atggggaatt aaaagtaatt cattcagtta
    11521 aggtggcaac tacaaaagat gttgaaactg gtgtttacaa tgccttaaaa aaagttatag
    11581 atgaaagtaa gattgaccat tcattaataa aatatgctat gcttggtaca actcattgta
    11641 caaatgctat tgtagaaaga aaaagactta ataatgtggc tatgataaga ataggaaagc
    11701 cagccactac tgccattctt ccatttatag attggccaga agacttaaga gaaaaaatag
    11761 aattagattc aatattggta tctggtggat atgagtttga ttaaaaaata gctacgcaca
    11821 ctcgtgactt tagtcatgag ttagtagcta aaatagtcag catataggga aacctatatg
    11881 tagagatagg ata
//
LOCUS       DAEPHU010000103        11393 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 01A10CD0081
            SAMN05941466-rid12468953.denovo.103, whole genome shotgun sequence.
ACCESSION   DAEPHU010000103 DAEPHU010000000
VERSION     DAEPHU010000103.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941466
            Sequence Read Archive: SRR6291087
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 11393)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11393)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068158.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 22:43:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,892
            CDSs (total)                      :: 3,805
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 87
            rRNAs                             :: 8, 1, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 55
            CDSs (without protein)            :: 55
            Pseudo Genes (ambiguous residues) :: 0 of 55
            Pseudo Genes (frameshifted)       :: 21 of 55
            Pseudo Genes (incomplete)         :: 28 of 55
            Pseudo Genes (internal stop)      :: 16 of 55
            Pseudo Genes (multiple problems)  :: 8 of 55
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11393
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941466-rid12468953.denovo.103"
                     /strain="01A10CD0081"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            220..870
                     /locus_tag="KR231_003375"
     CDS             220..870
                     /locus_tag="KR231_003375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905011.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBH0005707.1"
                     /translation="MKVKSNLDEILYHKIIESLIRGEYSVGQKILLNDLCEKFEVSRT
                     PVVQAVKMLNKDGVLTIMTNGKVYVPEYEYDMVKQVCETRTLIETYALEKMMQEEEEV
                     FQQKLDVIKRYSDKCEEYYRQEKSVELALADLELHKAIVEGANNEILNDVYVGIQGRF
                     IVVNYLIRPLKNRNYEGTVQDHFEILKFIEDRDTKKAVDKLRNHIQGTIKRFCEDE"
     gene            1197..3263
                     /locus_tag="KR231_003376"
     CDS             1197..3263
                     /locus_tag="KR231_003376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S9 family peptidase"
                     /protein_id="HBH0005708.1"
                     /translation="MKEVVESLKKITKERIENTMKKLFTSETFLEYQFISDCQISPDG
                     GYTAFIVKKADIKENGYTSQVYILNNKTGELKQITSINSVGAYAWEDENTILFPALRN
                     EKVKEAVKNGKQCMSYYALSLNGGEAEELFRLPIKGGKLNPIGKGLYAVIDSYDNDRP
                     IVEGLPEEEQQKKINAYNKRHYEHFKEIPYAVNGEGYISRKRKRLYVYDSNINELKAI
                     TAPMFNVVGMKISDGKILYIGQEFKDVKGLKNGVYVFDTNTNTNVCILEKDKYIIKGF
                     ELYQNQVILNLTDALSYGNGENGDFYTIDIDTKEMKLLSGHQHHCIGNTVTSDVKMGA
                     GQTTKVDGEYIYYTSTVDMDCIIERIHIPTGKQEKVTQTGSVDFIDVKDGNIVCVGCL
                     GNGLPEVYTVENGTLCKKTHLNDHILEEYKISVPEYIESKGSSKWEIQGYVYKPVDYE
                     VGKKYPAVLAIHGGPRLTYGPYFMHEIQVFTSAGYFVFFCNPRGSEGRGNAFADIRKQ
                     FGDIDYIDFMEFTDTVLEKYTDIDKTKLAVEGGSYGGFMTNWIIGHTNRFAVACAQRS
                     IANWSGMEGTTDIGYYFCKGQTGASHMENHELQWKQSPLAYADKCVTPTLFLHGEKDY
                     RCYMQEAFQMFSALKIHGCPTKLCLFEGENHELSRSGRPKQKLQRLVEMLDWFSVYIK
                     KDNIGQ"
     gene            3280..5235
                     /locus_tag="KR231_003377"
     CDS             3280..5235
                     /locus_tag="KR231_003377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S9 family peptidase"
                     /protein_id="HBH0005709.1"
                     /translation="MEKIKIENSDIFEYIFPHDISCSPDGKHIAYIISNINEEKDCYE
                     HDLYVMDIKTEKQIHMTQTKDVTSFSWISNTELLFTSKRNKPKSGTTDFYTISIEGGE
                     AKKAFSIPKACSVPVSLGNKLWLLTTKNPTDSKKSEPDRAVEGVDYWTFTDKPFIRDG
                     ENFSQRRRVTLELYQEGENITKAITPKFCEVAGVDVSSDKNRILYTGQIYEDCATPFS
                     GLWEYHIDSGETKELVPQGKYQISLAKYIGKDKVMLQASTLDRSITQNHDIFILDLST
                     NEINMIASPDGMYATLLDVDAVYGGGRSNKVIGDKFIGARICRTMTEFNEFDTKTGNI
                     RIITKVDAFTSFDIYDNTMYTVMLKDYELAEIYSIDMTTGTMKKMTAFSKPYLDTHKV
                     SLPEKLTFVAKNKEEVDGFVIPPIDAKEGEKYPAVLFIHGGPKWAYGYMFTHLKQCVT
                     SKGMYVIYCNPHGGDGYGEKFLEMVERWGYVDYEHLMEFVDTCIEKYPGIDADRLGVA
                     GGSYGGYMTNWIIGHTDRFKAAVSQRGISNLITASLIIDFGDRIMKQTCGDKTPWNHE
                     EVLWNHSPIKYVKNVKTPTLFLHSDRDYRCFMGDTFQMFTALKQLGVDTEMYLFHGDT
                     HGLSRNGRPSNRIARANAIVDWFERYL"
     gene            5251..6441
                     /locus_tag="KR231_003378"
     CDS             5251..6441
                     /locus_tag="KR231_003378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="permease"
                     /protein_id="HBH0005710.1"
                     /translation="MSDMLLWFSVVLVLFAIGDLIASKTKAKVSAVFVTLLLFLILFV
                     TKAIPADIIEKAGMTAAASWSVPMIMFSMGTMLNVKQFIDEWRTVLTAWLGIVAVIVC
                     VSLCIPLFGKSTVLTSIPVINGALPATTIMTQAALEKGLTLAAATATVVFAIQKFIGT
                     PIASRAALQEANRLLVEYHEAKSKGIDLANVDTDKKEAENTGTKVKQAFCEKYDKYYS
                     TNVCIFFIALFSYLGYELSEIIHVNYSIVCLVVGVIVTRIGIVPKDILEKGKIKGFIN
                     MVVFAAVIPSLAKVSLTDLISLFVPIVGMFAASIIGIFLMMKVLPGWKIIGSKPLAFG
                     VGFCQMLGFPTTYLISNEVCNAVGETEEERAYLMSKIMPKLVVGGMACMISIVVAGLM
                     VPML"
     gene            7590..7964
                     /locus_tag="KR231_003379"
     CDS             7590..7964
                     /locus_tag="KR231_003379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBH0005711.1"
                     /translation="MKVLISNTSDKPLYQQIKEQIKEAIFTEELKEGDAMPSIRNFAN
                     DLKVSILTIRRVYEELENEGFLTRQVGIGTFISTGNLEILRDSKRRIVEQKMADMIKD
                     AKALGITQIELQEMMDILYEED"
     gene            7966..8823
                     /locus_tag="KR231_003380"
     CDS             7966..8823
                     /locus_tag="KR231_003380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH0005712.1"
                     /translation="MENILEVYNLNKTYTDFSLSNISFALPEDCITGFIGVNGAGKTT
                     TIRSILDVVKRDSGKIKIFGKDFDGNEKELKNRIGVVFDDSYFYEELSMAEMKSIIAP
                     SYDNWCEEDYQQNMKRFNLNPKQKIDTLSKGMKMKFALALALSHKAEFLIMDEPTSGL
                     DPLIRSQILDILTGYMKKCGRGVFFSTHITSDLDKIADMIVMIDNGRIILEREKDTLL
                     DEHRKVKGDIQFLNDETKKLFLNLEITGYGFIGITSKINEVQKNMPDILIERPTIEDI
                     MLAYIERRE"
     gene            8826..9464
                     /locus_tag="KR231_003381"
     CDS             8826..9464
                     /locus_tag="KR231_003381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-2 transporter permease"
                     /protein_id="HBH0005713.1"
                     /translation="MLIHLVKKDILIVKKYVLLILFIAIGIPLFILWRLPPFAQILGF
                     VLSIIFSEFMLCQYLLLKESQYSKASVLLCSTPYPRRGLVQSKYVLFAMVFIYCTLVY
                     WIENLLIPQIGTFDLTYILIVLLISSIIYGVYMPIQYKLGYETTKFFFVMIIMASSFV
                     LPLTIAHSNFEIPFIYQYPSMIVNIVLFLLSLIILLASMFISIKIFSNKELV"
     gene            10470..11204
                     /locus_tag="KR231_003382"
     CDS             10470..11204
                     /locus_tag="KR231_003382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HBH0005714.1"
                     /translation="MNLAKGLDVLKISSNVFGEDKVMYIPVIYTEDDATLIDTGLPGQ
                     GDLIIDALNKSNTSFDKLKNIIITHHDIDHIGNINYLREKSKNNIKVYAYKSEISYIT
                     GEETPFKLYMLEQMVDKIDDKMLSMLNVMGLGFKSSYTKVDVSLDNHEKLNLGEEIEV
                     IHTGGHTRGHICLYLKESKVLIAGDLLQVENGELKPVDVMYSNKQELKDAIKNISNYD
                     IETIVFSHGGLYQRNIIGTLKNLIIE"
BASE COUNT         4257 a         1304 c         1991 g         3841 t
ORIGIN      
        1 aatttgaagt acaacgattt aatctatagt acaataactt gatttgcaat acaatgaatt
       61 aatctatagt ataagagcat gatttacagt acaataattt aaattgtagt acaaaagtac
      121 tatcaaataa gaatttctac tttaaaaata ttactaaaag taattaaagt ccagtaattc
      181 aatataatat ggcaaaagaa tagaaataag gtgagagtag tgaaagtaaa gtcaaattta
      241 gatgaaattt tatatcataa gattattgaa agtcttattc gtggtgaata ctctgtaggt
      301 caaaaaatat tactaaatga cctttgtgaa aaatttgaag taagcagaac accagttgta
      361 caagcagtaa aaatgctaaa taaagatgga gtgcttacta ttatgacaaa tggtaaagtg
      421 tacgtaccag agtatgaata tgatatggta aaacaagttt gtgaaacgag aacactgatt
      481 gaaacatatg ctttagaaaa aatgatgcaa gaagaggaag aggtttttca acaaaagcta
      541 gatgtaataa aaagatactc tgataaatgc gaggagtact atcgtcaaga aaaatctgta
      601 gaacttgcac tagcagattt ggaattacat aaagccattg tagaaggggc aaataatgag
      661 attttaaatg atgtatatgt tggtatacaa ggaagattta tagtagtgaa ctatttaatt
      721 cgaccattaa aaaatcgtaa ttatgaagga acagtacaag accattttga aatattaaaa
      781 ttcattgaag acagagatac aaaaaaagca gtagataaac taagaaatca tattcaagga
      841 actattaaaa gattctgtga agatgaataa taagttttga agttactata tatacttatc
      901 tattaagttg ctaaatgtag tctaagtata atctaattat agtttaaaca taatctaaat
      961 ataatctaat aaatataatc taaatatagt gtaaataagt ctaagtatga attaaatata
     1021 gattaagtat agattaagta tagattaagt atgaattaag catgaattaa gcatggatta
     1081 aatatacttt aaattacaaa tattacaagg aagccagaag gcttcctaaa aaaataacct
     1141 ttataaaatt ttttatttta aatttaaaat tttttatttt aaatttaaaa taaaaaatga
     1201 aagaggtggt agagagtttg aaaaaaatta ctaaagaaag gatagaaaat actatgaaaa
     1261 agctatttac gagtgaaaca tttttggaat atcaatttat aagtgattgc caaatatcac
     1321 cagatggagg atatacagca tttattgtaa aaaaagctga tatcaaagag aatggttaca
     1381 caagccaagt ttatatatta aacaataaaa ctggcgaatt aaaacaaata acgtctataa
     1441 actctgttgg agcatatgcc tgggaagatg aaaatactat cttgttccct gctttgcgaa
     1501 atgaaaaagt aaaagaagct gtcaaaaacg gtaagcaatg catgagttac tatgctttat
     1561 ctttaaatgg tggagaagca gaagaacttt ttagactccc tatcaaaggt ggtaaattga
     1621 atcctatagg aaaaggtttg tatgcagtta ttgattctta tgacaatgac cgacctattg
     1681 tagagggatt gccagaagaa gaacaacaga aaaaaataaa tgcttataac aaaagacatt
     1741 atgaacattt caaagaaatt ccttatgctg tcaatgggga gggatatatt agcagaaaaa
     1801 gaaaacgcct atatgtatac gacagtaata taaatgagtt gaaggcaatt acagcaccta
     1861 tgtttaatgt tgtaggtatg aaaataagtg atggaaaaat cttatatata gggcaagagt
     1921 ttaaagatgt aaaaggtttg aaaaatgggg tctatgtatt tgatacaaac acaaacacaa
     1981 atgtctgtat attagaaaaa gataagtata ttataaaagg ttttgaatta tatcaaaatc
     2041 aagtgatact aaacctaact gatgctttat cttatggaaa tggagaaaat ggagattttt
     2101 atactattga tattgatacg aaagaaatga aacttctttc agggcatcaa catcattgta
     2161 ttggaaatac agtaacatct gatgttaaaa tgggtgctgg tcagacaaca aaggtagatg
     2221 gagaatatat ttattacact tctacagtag atatggactg cattattgaa agaatacata
     2281 ttccaacagg aaaacaggaa aaagtaacac agacaggttc agttgatttt atagatgtaa
     2341 aagatggcaa tattgtatgt gtgggttgtt taggaaatgg attaccagaa gtttatacag
     2401 tagagaatgg aacattgtgt aagaaaacac atttaaatga ccatatttta gaggaatata
     2461 aaatttctgt gccagaatac atagagtcaa aaggaagttc taaatgggaa atacaaggat
     2521 acgtatataa accagtagat tatgaggtgg ggaaaaaata tccagctgta ttggcgattc
     2581 atggaggacc aagattgaca tatggaccat attttatgca tgagatacag gtatttacaa
     2641 gtgcaggtta ctttgtattc ttctgtaacc caagggggtc tgaaggtcgt ggcaatgctt
     2701 ttgcagatat taggaaacag tttggagata ttgattatat agattttatg gaatttacag
     2761 atactgtact tgaaaaatat acagacattg ataaaacaaa attggctgtt gaaggtggaa
     2821 gttatggtgg atttatgacg aattggataa ttggtcatac aaaccgtttt gctgttgctt
     2881 gtgctcagcg ttctattgca aactggagtg gcatggaggg tacaacagac attggttatt
     2941 atttctgcaa aggacaaaca ggtgcttctc atatggaaaa ccacgagctt caatggaaac
     3001 agtcacctct tgcttatgct gataaatgtg ttacaccgac tttattttta catggtgaaa
     3061 aagactatag atgctatatg caagaagcat tccagatgtt ttcagcattg aaaattcatg
     3121 ggtgtcctac aaaactttgt ctatttgaag gagaaaacca tgaactgtct cgttctggta
     3181 gaccaaaaca aaagctacaa agattagttg aaatgctaga ttggttttca gtatatataa
     3241 aaaaagataa cataggacag tagaaaggag aatataaaaa tggaaaaaat aaagattgaa
     3301 aattcagata tttttgaata tatattccct catgatattt cttgttcacc tgatggaaag
     3361 catattgctt atattatatc aaatatcaac gaggaaaaag actgctatga acatgactta
     3421 tatgtgatgg acatcaaaac agaaaaacaa atacatatga ctcaaacaaa agatgtaaca
     3481 tcatttagtt ggatttctaa tacagaactc ctttttacat ctaaaagaaa taagccaaaa
     3541 tcaggtacaa cagattttta cactatttct atagaaggag gagaagcaaa aaaagcattt
     3601 tctattccaa aagcttgtag cgtacctgta tcacttggaa ataaattgtg gttactgaca
     3661 acaaaaaatc caacggattc taaaaaatca gaaccagata gggcagtaga gggtgtagat
     3721 tattggacat ttacagataa accttttata agagatggag aaaatttttc tcaaagaaga
     3781 cgtgtaacat tagaattata tcaagaaggt gaaaatataa caaaagccat tacaccaaaa
     3841 ttttgtgaag tagcaggtgt agacgtttct tctgataaaa acagaatttt atatactggt
     3901 cagatttatg aagattgtgc aactcctttt tctggacttt gggagtatca tatagacagt
     3961 ggtgaaacca aagaacttgt accacaagga aagtaccaaa taagtttggc aaaatatatt
     4021 ggcaaagata aagtaatgtt gcaagcttca acattagacc gttctatcac acagaatcat
     4081 gatattttta tacttgattt gagtactaat gaaataaata tgattgctag tccagatggt
     4141 atgtatgcta cattgctgga tgtagatgca gtatatggtg gtggacgtag taataaagtt
     4201 ataggagaca aatttattgg tgcaagaatt tgcagaacta tgacagaatt taatgagttt
     4261 gatacaaaga caggtaatat acgtatcatc acaaaagtag atgcttttac atcttttgat
     4321 atttacgaca acaccatgta cacagtaatg ttgaaagatt atgagttagc agaaatatat
     4381 agcattgata tgactacagg tacaatgaaa aaaatgactg ctttttctaa accatattta
     4441 gatactcata aggtttcatt acctgaaaaa ttgacgtttg tagcaaaaaa taaagaagaa
     4501 gttgatggtt ttgttatacc acctatagat gctaaagaag gcgaaaaata tcctgctgta
     4561 ttgttcattc atggtgggcc taaatgggca tatggctata tgtttacaca cttgaagcag
     4621 tgtgtaacat caaagggaat gtatgtgatt tattgtaacc ctcatggtgg tgacggttat
     4681 ggtgaaaaat tcttagaaat ggtagaaaga tgggggtatg ttgactatga gcatcttatg
     4741 gaatttgtag atacttgtat tgaaaaatat cctgggattg atgcagaccg cttaggggtt
     4801 gcagggggaa gttacggtgg ttatatgaca aactggataa ttggtcatac agaccgtttc
     4861 aaagcagcag tttctcaaag aggtattagt aacttgatta cagcttcttt aattattgac
     4921 tttggggata gaattatgaa gcagacttgt ggagataaga cgccttggaa tcatgaggag
     4981 gttctttgga atcattcacc tattaaatat gtgaaaaatg ttaagacacc aacattgttc
     5041 ttacatagtg atagggatta tagatgtttt atgggggata ctttccaaat gtttacagca
     5101 ttaaaacagc ttggtgtaga tacagaaatg tatttgtttc atggagatac acatggattg
     5161 tctagaaatg gaagaccatc taatagaatt gcaagagcaa atgctattgt agattggttt
     5221 gaaagatatt tataataagg gggttattct atgagtgata tgttattatg gtttagtgtc
     5281 gtattagttt tatttgctat tggggattta attgcaagca aaacaaaagc aaaagtatca
     5341 gctgtatttg ttacactact tttatttttg attctatttg tcacaaaagc aataccagct
     5401 gatattattg aaaaagcagg tatgaccgca gcagctagtt ggagtgttcc aatgattatg
     5461 tttagtatgg gaacaatgtt gaatgttaaa caatttatag acgaatggag aacagtattg
     5521 acagcatggc ttggaattgt agcagttata gtctgtgtct cattatgtat tcctttgttt
     5581 ggaaaatcaa cagtattgac aagcatacca gttataaatg gagctttacc tgctactact
     5641 attatgacac aagcagcact agaaaaagga ctgacacttg cagcagctac agcaacagtt
     5701 gtatttgcaa ttcagaagtt tattggtaca ccaatagctt caagagcagc gttacaagag
     5761 gcaaaccgtc ttttagtaga atatcatgaa gcaaaatcaa aaggcattga tttagcaaat
     5821 gttgatactg ataagaaaga agcagagaat acaggcacaa aagtaaaaca agctttctgt
     5881 gaaaaatacg ataaatatta ttctacaaat gtttgtatat tttttatagc attattctct
     5941 tatctagggt atgaactttc agagattatt catgtaaatt attctattgt atgtcttgtt
     6001 gttggtgtta ttgtaacacg tattggtatt gtgccaaaag acattttgga aaaaggaaaa
     6061 atcaagggat ttatcaacat ggttgtgttt gcagctgtta ttccttcttt agcaaaagtt
     6121 tctttgacag atttaattag tctttttgta ccaattgtgg gtatgtttgc agcttctatc
     6181 attggtatat tccttatgat gaaggtgtta ccaggttgga aaattatcgg ttctaaacct
     6241 cttgcttttg gagtagggtt ttgtcagatg ttgggattcc caactacata tttaatttca
     6301 aatgaagtgt gtaatgctgt tggagaaacg gaagaagaaa gagcatattt gatgtctaag
     6361 attatgccta agctggtagt tggtggtatg gcttgtatga tttctattgt ggtagctggt
     6421 cttatggtac caatgttgta gataggtttc atagttaaaa aagtggtatt aatttatagg
     6481 agaagctaaa aagtagtatt aatttataaa ataattttat attagttaat ttgttataag
     6541 aatattttct ttttataatt ataattttga ttttataaga tagcagattt tttatttgct
     6601 atgctaatag ttataatttg tttttatttg ctaaaatgca actttaattt gatttatgta
     6661 taatataggg tatttaataa tatttttgaa gaatttttat aaaaaattaa aaagaggaga
     6721 aaaaagggag tgccacaaag tgaacttttt agttctaagg cactcttttt tgtacgaaat
     6781 cgaatatatt ttcaacgttt taaaagtgag aaagagactt atctctagtt tgagatagcc
     6841 aattttaatt attaaaatta ttttttgttt tatttatcaa agagtattcg tgttttagaa
     6901 gttagtattt tttattttat atatacaagg ttttccgttt ctaatgtttt cttttttaaa
     6961 ataattaggg tattcaatta tagtaaaagg tggatggtat tttggagtga tattatttaa
     7021 agcacagtat tgaatgttga aatcctcaca ttttagagta ttatcttttg taatcaaaaa
     7081 aatcttctat acttatagca aggttacttc tgcaaatatt ccatacataa taatatccca
     7141 atttaaattt ttttaatata gagtttacct ctagtctaca ctcttgaata actctttcct
     7201 ctatccaaat tcttataaat tcatcccatt tattactatt tatttattat tatctaaatt
     7261 ttttagtatg tttgtaatta gaaatggatt tattccttta tgttttttat aaatagttta
     7321 taacttaatt tatcattaaa caaatcattc atacaggatt actttttctt ttatatattc
     7381 aattcttact tttaataaat atttaataca tcctatctta tgtagtttta aaaagtgttt
     7441 atggctatta acaatctcta atatttcatt catatttatt ttgtcatagt aatattttac
     7501 atcttttata ttgacaaaaa agtgctctaa gtgtatagtg tgtatatgat aacatcacac
     7561 tgaaagtgat aaaaaggggg tgataaaaaa tgaaagtgct catttctaac acatcagata
     7621 agccattata ccaacaaatt aaagagcaaa ttaaagaagc aatatttact gaagaactga
     7681 aagaagggga tgcaatgcca tccataagaa attttgctaa tgatttaaaa gttagtattt
     7741 tgactattag acgagtgtat gaagaacttg aaaatgaagg ctttcttaca cgccaagttg
     7801 gaataggaac atttatttca actggaaatt tagaaatact aagagactca aagagacgta
     7861 tagttgaaca aaaaatggca gatatgatta aagatgcaaa agcactagga attacacaga
     7921 tagagttaca agaaatgatg gatattctat atgaggagga ttaatatgga aaatatttta
     7981 gaagtttata acttaaataa gacttatacc gatttttcat tatctaatat aagctttgca
     8041 ttaccagaag attgtataac cggatttata ggtgttaatg gagcaggaaa aacaacaaca
     8101 atccgttcga tattggatgt cgtaaagcgt gatagtggaa aaataaaaat ctttggtaaa
     8161 gatttcgatg gaaatgagaa ggaattaaaa aatcgaattg gagttgtctt tgatgattca
     8221 tatttctatg aggagttgtc aatggcagaa atgaaaagta ttattgcacc ttcatatgat
     8281 aattggtgtg aagaagatta tcaacaaaat atgaagcgtt ttaatcttaa cccaaaacaa
     8341 aagattgata cactttcaaa aggaatgaaa atgaaatttg ctttagcatt agcattatcg
     8401 cataaagctg agtttttaat tatggatgag cctacaagtg gtttagaccc actaatccgt
     8461 agtcagatac ttgacatact aacaggatat atgaagaaat gtggtcgtgg tgttttcttt
     8521 tccactcata taacatctga tttagacaaa atagcagata tgattgttat gattgacaat
     8581 ggacgtatta tattagagcg tgaaaaagat actctattgg acgaacatag aaaagtaaaa
     8641 ggggatattc aatttctaaa tgatgaaacc aaaaaattat ttttaaattt agaaattaca
     8701 ggttatggtt ttatagggat tacctcaaaa attaatgaag tgcaaaaaaa tatgccagat
     8761 attttaatag agcgtcctac aattgaagat attatgcttg catatattga aaggagagag
     8821 taattatgtt gattcattta gttaaaaaag atattctgat tgtaaaaaaa tatgtattgt
     8881 tgatattatt tattgcaata ggaatcccat tatttatatt atggcgttta cctccatttg
     8941 cacaaatatt gggatttgta ctatcaatta tattttcaga atttatgctg tgtcagtatc
     9001 tattattaaa ggagagtcaa tattcaaaag catctgtatt actttgttca actccttatc
     9061 ctagacgtgg cttagttcaa tctaagtatg ttttatttgc aatggtattt atctattgta
     9121 cattagttta ctggattgaa aatttactta ttccacaaat aggaactttt gacttgacat
     9181 atattttgat tgttttatta ataagttcta ttatttatgg agtttatatg cctattcaat
     9241 acaaattagg atatgaaaca acaaaattct ttttcgtgat gataatcatg gcttcatcat
     9301 ttgtattacc attaactata gctcacagca attttgaaat tccatttata tatcagtatc
     9361 catccatgat agtgaatatt gtattgttcc ttttaagttt aattatactg ttagcttcaa
     9421 tgtttatttc tattaaaatt tttagtaata aggagcttgt ataaggtaag ggggactttt
     9481 atatgccaca tttaccagat tgggctgttt tactttgtat cttacttcca atagtatata
     9541 aagcttgtca gatatttaaa agtaaaaaat agagtatata tttatattgc catttttatt
     9601 gagtgaagtt agatggtatg aaaaggttac ttgaaaataa agttacttgg tgtgggagag
     9661 taacatcata atattataga ttatatgttt cttgtgaatc aatttgtatt ttttaatagg
     9721 gaatatccag taattttgtt ttccattgat tatttttcaa ttatgagtat gattgtgtgt
     9781 attgtatacc atcttttaag gtgtttttaa aaaattatat cgtcaaaata taaatctaag
     9841 gaatcctata aataaagctt tttaatttta gaaaactaat aaaaagtagg acgttaataa
     9901 aaagaagctg tctcaaaata gagataagct tctttttcat tgctgaaatg acgaaaatat
     9961 aattgattta atataaaaaa gagtgcttta tgaactattt attttgaaca gtagatacac
    10021 ttgcactcaa tttagttact cctaagcttt atgaactaaa agtttatttt gaagcttatt
    10081 tttattaaaa gagattttat ttttctaaat aatcatctat atacagtatt gcgtttcttt
    10141 tatttattca taatttattt tcttattaaa gtttttctat attcatattt tctatattac
    10201 tttactttta attttatacg aattatcaaa aataaaatag ttattagaaa aaaataaaag
    10261 taattgcaaa gcttgcaatt acttacttct atattaatta ctataccata aaataacaaa
    10321 aaaatcaagt cgagtaatcc ttcaacttaa atgatatact aggtattaat aatttttaat
    10381 taataaaata taactagagg aaaatctaca ttttctcaat ttctttaatt aaattgacct
    10441 ctaattaagt aattataagg agaaaaatta tgaatttagc aaagggatta gatgttttaa
    10501 aaatttcatc aaatgtattc ggtgaagata aagttatgta tattcctgta atctacacag
    10561 aagatgatgc aacacttatt gacacaggtc ttccgggtca aggtgattta ataattgatg
    10621 ctcttaataa aagtaacacg agctttgata agttaaaaaa tataataatc actcatcatg
    10681 atatagacca tataggaaac ataaattatc taagagaaaa atctaagaat aatatcaaag
    10741 tatatgcata caaaagtgaa atcagctata taacaggaga agaaactcct tttaaacttt
    10801 atatgttgga acaaatggta gataaaattg atgataagat gcttagtatg ctaaatgtta
    10861 tgggacttgg atttaaatca tcatatacta aagtagatgt gtcattagat aaccatgaaa
    10921 aattgaatct aggtgaggaa atagaagtta tacatacagg aggtcacact agaggtcaca
    10981 tatgtcttta tttaaaagag tctaaagtac ttattgctgg agatttgtta caggtagaaa
    11041 atggagaact taagcctgtt gatgtgatgt acagcaacaa acaagagtta aaagatgcta
    11101 ttaaaaatat aagtaattat gatatagaaa cgatagtttt tagtcatggt ggattatatc
    11161 aaagaaacat aattggaaca ttgaaaaacc taattattga gtagtactat atgatttaca
    11221 ataatttctt aaattactta aaattatatc taaagatgta gaatcaaaat taaatataag
    11281 taataagaat tttgctttaa aattatactt aagtgttaag ggtgatatgt agtattacaa
    11341 gtattttaga atataatttt ttatagtaat tttaaagttc tacaatactt cag
//
LOCUS       DAEPHU010000104        11083 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 01A10CD0081
            SAMN05941466-rid12468953.denovo.104, whole genome shotgun sequence.
ACCESSION   DAEPHU010000104 DAEPHU010000000
VERSION     DAEPHU010000104.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941466
            Sequence Read Archive: SRR6291087
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 11083)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11083)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068158.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 22:43:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,892
            CDSs (total)                      :: 3,805
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 87
            rRNAs                             :: 8, 1, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 55
            CDSs (without protein)            :: 55
            Pseudo Genes (ambiguous residues) :: 0 of 55
            Pseudo Genes (frameshifted)       :: 21 of 55
            Pseudo Genes (incomplete)         :: 28 of 55
            Pseudo Genes (internal stop)      :: 16 of 55
            Pseudo Genes (multiple problems)  :: 8 of 55
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11083
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941466-rid12468953.denovo.104"
                     /strain="01A10CD0081"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            269..715
                     /locus_tag="KR231_003383"
     CDS             269..715
                     /locus_tag="KR231_003383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0005715.1"
                     /translation="MAISDLAFGTECLKTSFQMLFSVISLVNINLLQAQILIAIGGLI
                     SILAMVSLTLFLSAKCKDSLTSMLIAFSICLIPMGIGVSWIGYLLPPGGIGFKISLLY
                     QMTSFNFLHLGGMSFWTPHIILFFSVIEIPIFIFLAIRTYCKHQVP"
     gene            1096..2013
                     /gene="pstC"
                     /locus_tag="KR231_003384"
     CDS             1096..2013
                     /gene="pstC"
                     /locus_tag="KR231_003384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease subunit PstC"
                     /protein_id="HBH0005716.1"
                     /translation="MIVKSRLVGLEKNDNNGNKTKYVIEKVAKNIFLLSALVAVASLL
                     LIIGFVFYKGLRPFIFEGYSFIDFLTGADWVPSANKFGISSMIVASIFATLGALVIGV
                     PVGILTSVFIAEVAPKRLAKIMSPAVELLAGIPSVLYGVFGLAVIVPTIQGIFNLPKG
                     QSLLAIVIVLAVMMLPTIISVSETAIRAVPKAYKEGSLALGASKIETIFKVVLPAAKS
                     GVLAAVVLGVGRALGETMAVILVAGNSPVMPTAITDSVRPLTTNIALEMGYAFGTHQE
                     MLFATGVVLFTFILILNLVLNKLSNKAVN"
     gene            2015..2839
                     /gene="pstA"
                     /locus_tag="KR231_003385"
     CDS             2015..2839
                     /gene="pstA"
                     /locus_tag="KR231_003385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003460575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease PstA"
                     /protein_id="HBH0005717.1"
                     /translation="MRKFKENLLKSLVYLSALFTIVSLVVIVGFIFIKGIGNMNFNFL
                     FSNYSASGDGGILPMIITTLYTVVVSIVVATPIGILAAIYLQEYAKKGKAVTAIRFAT
                     ESLSGIPSIVYGLFGGIFFVVTLKMGYSIVAGSLTVAIIILPVIIRTTEEALKTVPQA
                     YRESSLALGATKFQTLYKVVLPSAIPGILSGVILSVGRIIGESAAILLTAGTVAKMPG
                     GIFDSARTLTVHSYLLTKESGDIATAASIGIVLIVIVLALNMLARFVAKKLNKANY"
     gene            2858..3622
                     /gene="pstB"
                     /locus_tag="KR231_003386"
     CDS             2858..3622
                     /gene="pstB"
                     /locus_tag="KR231_003386"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HBH0005718.1"
                     /translation="MELIDKIKMSVKDLDLFYGDKQALKKINMDIKENKVTALIGPSG
                     CGKSTFIRTLNRMNDLIEDVTIKGNISVDGEDIYTSDDVINLRTKVGMVFQKPNPFPM
                     SIYDNVAYGPRTHGLRDKKQLDKIVEESLKGAAIWDEVKDRLKSSALGLSGGQQQRIC
                     IARAIAMRPEVILMDEPTSALDPISTLKVEELIEDLKKDYTIVIVTHNMQQAARISDE
                     TAFFLNGEVIEFSDTKTMFTTPVDKRTEDYITGRFG"
     gene            3650..4303
                     /gene="phoU"
                     /locus_tag="KR231_003387"
     CDS             3650..4303
                     /gene="phoU"
                     /locus_tag="KR231_003387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate signaling complex protein PhoU"
                     /protein_id="HBH0005719.1"
                     /translation="MVNNSLDISIDTLKEQTVLMMEKCEEAIEKSVTCMIEKDLEGAR
                     KVVEDDEEINKLREEIRDKSIELIVLKQPMARDLRFIYSLGNISIELERIGDYAANIA
                     REMLKIGGEAYIKELIDIPKMAKECKSMMSQTREALILFDASIAYDVGTKDDIVDGLY
                     EQVQIDCLKIMHENSNTIDQGVKLLLIGRYLERIGDHITNVCEKIIFAIEGKMVEIG"
     gene            4461..5330
                     /locus_tag="KR231_003388"
     CDS             4461..5330
                     /locus_tag="KR231_003388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422131.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HBH0005720.1"
                     /translation="MKLQKMGMRTIKTGISVTLCMILGDYLVENMFYSLVACIISVQD
                     TVKGSLKTGINRVEGTILGGIIGFIFAIIKAGDPFLCGLGVMCSIYLCNLFKIKSVVV
                     ACVTFLAIHLGVGNSDPVYYSLHRVLDTSVGVLFGVLVNYYVARPNYLNSVIDEFKKI
                     EELSMLLIEDKILRKENLNVEKFEEEVEKLEEIYSKLIDELDYSLSETNIEKIENALR
                     ICREIHFHMQSIELLENKLYLKEHTYKYLKKTYNVDKLDWNIDEEKSPVFNYHLMKIM
                     IEIELLRKLNKSY"
     gene            5417..6853
                     /locus_tag="KR231_003389"
     CDS             5417..6853
                     /locus_tag="KR231_003389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron hydrogenase"
                     /protein_id="HBH0005721.1"
                     /translation="MNTRNDNSKILEIYKMKLFGELVKAVWNDDIEDIENLPNKILNE
                     DLKDNLNNYFSGKFDKDTMVNLIRVTMGLDVTEDTDKNLKESLHEAVNLDEVKRPIIS
                     VISDACKYCDENNKEDESCKIRSKHINCNEEDVCSACGDCVSRCKLGAISDKIEFIPM
                     IKLLKDIKSPVYAIVAPAFVGQFGKDVSPGKLRTALKKIGFEDMIEVALAADMLTAKE
                     AYDYYEHMKKDEEGCFITSCCCPIWVSLIQNSFPQILENVSPSVSPMIACGRAVKILN
                     PDAKVVFIGPCMAKKKEAMLEDIKDAVDFVLTFKELQEIFDALELNPAIMDESNRVEA
                     SLSGRVYARTGGVSKAVKLSVRRIDKNIKFEEKAFEGTKECMDGLKKVLNKEIEATFI
                     EGMGCVGGCVGGPKRILSVEEGTKNVDEYSESTNMETPFDNLNVLQFLTSLGIKRVES
                     LGEKEEEKVKKIFSRDIKSNKKENKYKK"
     gene            6901..7728
                     /locus_tag="KR231_003390"
     CDS             6901..7728
                     /locus_tag="KR231_003390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HBH0005722.1"
                     /translation="MKIKDNKAVFHVFIRIFLIAVLILTGTLLEEKINNVPVENISSK
                     GENTLELLSQSNTLGEIIYKASQEETKGPGATSEKVAYITIDDGPSKYTNALLDILKE
                     NDVKATFFMLNQNMKNHKEEVRRVLEEENSIGFHSVSHDIHKLYKSPEVTVGEFNTCN
                     NTLQEITGQSSKLIRLPYGSKPYMPEGSYNKLMANDYLIWDWNLDTQDWKSSTSQIVS
                     NILYYGRKRDELVVLIHEKEQSLNALNNIIRILKERGYTILPITENITPKNFWQENL"
     misc_binding    8024..8286
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            8362..11028
                     /locus_tag="KR231_003391"
     CDS             8362..11028
                     /locus_tag="KR231_003391"
                     /EC_number="6.1.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="valine--tRNA ligase"
                     /protein_id="HBH0005723.1"
                     /translation="MENTNLSKTYNPKDFEARLYKKWMDEGYFKSKPNPDKKPFTIMM
                     PPPNITGQLHMGHALDHTLQDILIRWKRMDGYEAFWLPGTDHASIATEVKVVERIKKQ
                     EGKTKYEIGREEFLKRAWEWKDEFGGKISNQLKQLGDSCDWDKERFTMDEGCNEAVIE
                     FFVSLYEKGHIYRGNRIINWCPDCKTTLSDAEVEHEEHDGNFYHIKYPLKDSEDFLEI
                     ATTRPETMIGDTGIAVNPEDDRYKHLIGKTAILPLVGRELPIVADSYVDLEFGTGAVK
                     MTPAHDPNDFEVGLRHNLEQLNTMNEDGTMNEVCGKYEGMDRFECRKAIVADLKEQGY
                     LIKIKEHNHNVGTCYRCHTVVEPRLSEQWFVKMEELAKPAIDILKKGELEFVPDKFDK
                     TYLQWLENIRDWCISRQLWWGHQIPAYYCQECGEIVVARKMPDKCPKCGSTHFKQDED
                     ALDTWFSSALWPFSTLGWPNKTEALDYYYPTSVLVTGYDIIFFWVVRMAFAGMFCMNE
                     KPFDHVLVHGLVRDSQGRKMSKSLGNGIDPLEIIEQYGADALRFTLTTGNSPGNDMRF
                     YMERVEFARNFANKLWNASRFVFMNIDEDIIKNMTRESVKEDLTLADKWIISRANNIV
                     KEATNNMDKFDLGIALQKIYDFTWSEYCDWYIEMVKPRLYGEDANAKSAALYTLTYVL
                     EKILKLLHPYMPFITEEIYTHLPTVEGCIIVSEWPKYNEEDNMAEEEDMMNLLMEGIR
                     SIRNVRAEMNVPPSKKAKLIIIPSEEKIEAIELGKDYFITLASASNVEIAKDKSNVPE
                     DAVGVVIDGVEIFIPLNELVDFEKEIERLSKEKKKLEGEIKRVNGKLANQGFLAKAPE
                     SLIEEEKAKKEKFEEMIKSVEERLTNLESKIK"
BASE COUNT         4385 a         1190 c         2078 g         3430 t
ORIGIN      
        1 atattaaata ataaaatagt taaataataa gattaagaat ttcttaataa atccagaaga
       61 tgctttcgat tatataatat tttatatttt tatattatta attatatgtg ttgcaatcgc
      121 tgcacctact ttttctggtg agtatcagac acaatcagat agcatccttc gttgtacgaa
      181 acatggacat attcgtctag cgtttactaa aatattagct ctattttcta tatttataat
      241 aatgtttgtt atatgtattt ctatccattt ggcaatttct gatttagctt ttggtactga
      301 atgtttgaaa acctcatttc aaatgttgtt ttctgtcatt agtctagtaa atataaattt
      361 actacaagca cagattctta tagctattgg tggtctaatt tcaatacttg caatggttag
      421 tttaacatta tttttatctg caaaatgtaa ggattctctt acttctatgc tgattgcttt
      481 ttctatttgc ttaattccta tgggaatagg tgttagttgg attggatacc tattaccacc
      541 agggggaatt ggttttaaga ttagtttatt atatcaaatg acatcattta atttcttaca
      601 cttaggaggt atgagttttt ggacaccaca cattatactg tttttctcag tgatagaaat
      661 acctattttt atatttttgg ctattcgtac ctattgcaaa catcaagtac cgtaacaatt
      721 tgatggaaat aatagtgata taaactagag gatacaataa ttatatatgt agtataaaag
      781 ttaaatttag ttaacaaatc ttaatagcag atataggtaa taaattatac ataaactgta
      841 ttattatcta tatctgctat tttaatatag agaaacaaca gtatattgta aagtaaatgt
      901 caaatatagt tttaaaagta aaattaatgt taaaaagtaa atataatttt acacttgctt
      961 aacttaatcc taatatagat ttaacttaaa aaaagtagaa taaaagtata ggaaatttga
     1021 tgaagacgaa ttataaaaaa ttaaattttg aatacagaac gaaaatcgat aagtatattt
     1081 taatgggagg gtattatgat agtaaaatct agattagtag gtttagaaaa aaatgacaat
     1141 aatggcaata agacaaaata cgtaattgaa aaagtagcaa aaaatatttt tctacttagt
     1201 gctttagtag cagttgcaag tttacttttg ataataggat tcgtatttta taaaggatta
     1261 agaccattta tatttgaagg atattcattt atagactttt taactggtgc agattgggtt
     1321 ccttctgcca ataaatttgg aatatcatct atgatagtag catcaatatt tgcaacactt
     1381 ggagcacttg ttataggagt acctgttggt atattaacct ctgtatttat agcagaagta
     1441 gcacctaaaa gattagcaaa aataatgtca ccagcagttg aacttttagc aggtatacct
     1501 tcagtattat atggtgtatt tggtcttgca gtgatagttc caactataca aggtatattt
     1561 aatcttccaa aaggtcaaag tttgttagca atagtaatag tattagcagt aatgatgtta
     1621 ccaacaataa tatctgtatc agaaacagca ataagagcag taccaaaagc atacaaagaa
     1681 ggttcattag cacttggtgc atcaaaaata gaaacaatat tcaaagttgt attacctgct
     1741 gcaaaatctg gagtattagc cgcagtagtg ttaggagtag gaagagcttt aggtgaaaca
     1801 atggcagtaa tacttgttgc aggcaactca ccagttatgc caactgcaat aacagatagt
     1861 gtaagaccac ttacaactaa tatagcactt gaaatgggat acgcatttgg tacacatcaa
     1921 gaaatgctat ttgcaactgg agtagtattg tttacattta tattaatttt aaacttagtt
     1981 ttaaataaac tttcaaataa ggcggtaaat taagatgaga aagttcaaag agaatctatt
     2041 gaagtcatta gtatatctat cagcactatt tacaatagta tcattagtag ttatagtggg
     2101 atttatattt ataaagggaa ttggcaacat gaattttaat ttcttattta gcaattattc
     2161 agcatcaggt gatggtggta tacttccaat gataattaca acattatata cagtagtagt
     2221 ttctatagtt gtagcaactc ctataggaat attggctgct atatatttac aagaatatgc
     2281 taaaaaagga aaagcagtta cagctataag atttgcaact gaaagtttat cagggatacc
     2341 atctatagta tatggattat ttggaggaat tttctttgta gttacattaa aaatgggata
     2401 ttccatagtt gcaggttcac ttacagttgc aataataata ttaccagtaa taattcgtac
     2461 aacagaagaa gctttaaaaa cagttcctca agcttataga gaatcatcat tggcattagg
     2521 agctacaaaa tttcaaactt tatataaggt agtacttcca agtgcaatac caggaatttt
     2581 atctggagta atcttatcag ttggtcgtat aattggagaa tcagctgcaa tattacttac
     2641 agcaggtact gtagccaaga tgccaggtgg aatatttgat agtgcaagaa cattaactgt
     2701 acactcatac ttactgacta aagagagtgg agatatagca acagcagcca gtataggaat
     2761 tgttttaata gtaattgtat tagcactaaa catgctagca agatttgttg ctaagaaatt
     2821 aaataaagct aattattaaa tttaagaggt gtgaataatg gaattaatcg ataagataaa
     2881 aatgagtgta aaagatttgg atttatttta tggtgataag caagcattaa agaaaataaa
     2941 tatggatata aaagagaata aggttactgc tttaataggt ccatctggat gcggaaaatc
     3001 aacttttata agaacgttaa atagaatgaa tgacttaatc gaagatgtaa caattaaagg
     3061 aaacatttct gttgatggag aggacatata tacctcagat gatgttataa atcttcgtac
     3121 taaagtagga atggtatttc aaaagccaaa tccatttcct atgagtatat atgataatgt
     3181 ggcatatggt cctcgtacac atggactaag agataagaag caattagata aaattgtaga
     3241 agaaagctta aaaggtgcag ctatttggga tgaggttaaa gacaggctta aatcatctgc
     3301 actaggactt tctggtggtc aacaacagcg tatatgtata gcaagagcaa ttgctatgag
     3361 accagaagtt attcttatgg atgaacctac atctgcttta gacccaattt caacattaaa
     3421 agtagaggaa cttatagagg atttaaaaaa agactacaca atagtcatag ttacacataa
     3481 tatgcaacaa gctgctcgta tatcagatga aacagctttt ttcttaaatg gagaggttat
     3541 agaatttagc gatacaaaaa ctatgtttac cactcctgta gataaaagaa cagaagacta
     3601 tataacaggt agatttggtt aaaatatata actataaagg agttagacaa tggtcaataa
     3661 tagtttagat ataagtattg atactttaaa agaacaaaca gtgcttatga tggaaaaatg
     3721 tgaagaagca atagaaaagt ctgtgacttg tatgatagag aaggatttag agggtgcaag
     3781 aaaagtagta gaagatgatg aagaaataaa taaattaaga gaagaaataa gagataagag
     3841 tatagagcta atagtattaa agcaaccaat ggcaagggac ttaagattta tttattcatt
     3901 aggtaatata tctatagagc tggaaagaat aggagattat gcagcaaata tagctagaga
     3961 aatgttgaag ataggtggag aggcttatat aaaagagcta atagatattc ctaagatggc
     4021 aaaagaatgt aagtctatga tgtctcagac tagagaagct ttaatcttat ttgatgcaag
     4081 tatagcttat gatgttggaa ctaaagatga tattgtagat ggattgtatg aacaagtaca
     4141 aattgattgt ttaaaaataa tgcatgaaaa ctcaaatacc atagaccaag gggtaaaact
     4201 tctacttata ggaagatacc ttgaaagaat tggagaccat ataacaaatg tatgtgagaa
     4261 gataattttt gcaattgagg gtaaaatggt tgagatagga taaaaaactg ctttaaagca
     4321 gtttttttat tgtctaaatt aagaaagaat tgataaaaaa atatgattaa tgggtaaatt
     4381 taaaaaattg tgatatacta ggaacatatt aaatatgagg atgcgtattt tatataaggt
     4441 gctttttagg aggtggaact ttgaaacttc aaaagatggg tatgaggact ataaaaacag
     4501 gaattagtgt cactttatgt atgattcttg gtgactattt agtagagaat atgttttatt
     4561 ctctggtagc atgtataatt tctgttcaag atacagtaaa aggttcttta aagacgggaa
     4621 tcaatagagt ggaaggtact attttaggtg gtataatagg attcatattt gcaatcatta
     4681 aagctggaga cccattttta tgtggtctag gagtaatgtg ctcaatatat ttatgcaatc
     4741 tgtttaaaat aaagtcagta gtagttgcct gtgtaacctt tctggctata catctaggtg
     4801 taggaaatag tgaccctgtg tattattctt tacatagggt gttagataca tctgtgggtg
     4861 ttttgtttgg agtacttgtt aattattatg ttgctagacc aaattatcta aatagtgtta
     4921 tagatgagtt taaaaagata gaagaacttt caatgttgct tattgaagat aaaattctta
     4981 gaaaagaaaa tttaaatgta gagaaatttg aagaagaagt agaaaaatta gaagaaatat
     5041 attcaaaact tattgatgag ttggattata gtttgagtga aactaatata gaaaaaattg
     5101 agaatgcctt aaggatatgt agagaaatac attttcatat gcagtctata gagttacttg
     5161 aaaataaact ttatttgaaa gagcatacat ataaatacct taagaaaaca tataatgtgg
     5221 ataagctaga ctggaatata gatgaagaaa aaagccctgt attcaactat catctaatga
     5281 aaataatgat tgaaatagag ttgttgagaa agctaaataa atcatattaa taatagtagt
     5341 taaataataa ataaaaaata gtatctttgt aaatattaaa catatataag tttaatttat
     5401 ggaggtacta ttttttatga atactagaaa tgacaattct aaaatactag aaatatataa
     5461 aatgaagctt tttggcgaac ttgtaaaagc agtgtggaat gatgatatag aggatattga
     5521 aaacttacct aataaaattt taaatgaaga tttaaaggat aatttaaata attattttag
     5581 tggaaaattt gataaagata ctatggtaaa tttaattagg gtaactatgg gattggatgt
     5641 tacagaagat acagataaaa atttaaaaga gtcactgcat gaagctgtaa atttagatga
     5701 agtcaaaaga ccaataatat ctgtaatatc agatgcttgc aaatattgtg atgaaaataa
     5761 taaggaagat gagtcatgta agataagaag taagcatatt aattgtaatg aggaagatgt
     5821 atgtagtgct tgtggtgatt gtgtatcaag atgtaagttg ggtgcaattt cagataaaat
     5881 agaatttata ccaatgataa aattgttaaa agatataaag agccctgtat atgcaatagt
     5941 tgcaccagct tttgtaggac agtttgggaa agatgtaagc cctggtaaat taagaactgc
     6001 attaaaaaag ataggatttg aagatatgat agaagttgct ttggcagcag atatgcttac
     6061 tgcaaaagaa gcatatgatt attatgagca tatgaaaaag gacgaagaag gatgctttat
     6121 aactagttgt tgctgtccta tttgggttag tttgatacaa aatagttttc ctcagatatt
     6181 ggaaaatgta tcaccatccg tttctcctat gattgcttgt gggagagctg taaaaatttt
     6241 aaatccagat gctaaagttg tattcatagg tccttgtatg gcaaaaaaga aagaagcaat
     6301 gttagaagat ataaaagatg cagttgattt tgtgcttaca tttaaagagt tgcaagaaat
     6361 atttgatgca ttagagttaa atccagcaat aatggatgag agtaatagag tagaggcgtc
     6421 cctttcaggt agagtttatg ctagaacagg aggtgtaagt aaagcagtta agttatcagt
     6481 tagaagaatt gacaaaaata taaaatttga agaaaaggca tttgaaggaa caaaagagtg
     6541 catggacggt ctaaagaaag ttctaaataa agaaatagaa gctacattta tagaaggaat
     6601 ggggtgtgta ggaggctgtg taggaggtcc gaagcgtatt ttaagtgtgg aagaaggtac
     6661 taagaatgtt gatgaatata gtgaaagtac gaatatggaa actccatttg ataatttaaa
     6721 tgtattacaa tttttaactt ctttgggaat caaaagagta gaatctttag gagaaaaaga
     6781 agaagaaaag gttaaaaaaa tatttagtag agatataaaa agtaataaga aagagaataa
     6841 atataaaaaa taacttttta agtcttaaac ttatgctttt ataaaaggga gatatggggg
     6901 atgaaaatta aagataataa ggctgttttt catgtattta taaggatatt tcttatagct
     6961 gttttaattt taactggaac attattggag gaaaaaatta ataatgttcc agttgaaaat
     7021 ataagttcaa aaggtgaaaa tacactggaa ctgctttctc aaagtaatac tttaggagaa
     7081 atcatataca aagcatctca agaagaaaca aaaggtccag gggctacttc tgaaaaagta
     7141 gcatacataa caatagatga tggtccatca aaatatacaa atgcactact tgatatttta
     7201 aaagaaaatg atgtcaaagc gacatttttc atgcttaatc agaatatgaa aaaccacaag
     7261 gaagaagtaa ggagagtctt ggaagaagaa aactcaatag gttttcatag tgtaagtcat
     7321 gatatacata agttatataa aagcccagaa gtaacagttg gggaatttaa tacatgcaat
     7381 aatactctac aagaaataac tggtcagagt tcaaaattaa taagattacc atacggaagt
     7441 aaaccatata tgccagaagg ttcatataat aaacttatgg caaatgatta tttaatttgg
     7501 gactggaatt tggatacaca ggattggaag tcttctacaa gtcagatagt aagtaatata
     7561 ttatattatg gaagaaaaag agatgaatta gtagtattaa ttcatgagaa agagcaaagt
     7621 ttaaatgctt taaataatat tataagaatc ttaaaagaga gaggatatac aatattgcca
     7681 attacagaaa atataacacc taaaaatttc tggcaagaaa acttataata aatttaaata
     7741 tagtaaaaga taaagtaaat tatttataaa ataaaacata taatataaaa aatacgaata
     7801 agaggtatac tgtaaggata atataaaatt aatgagaaag cattaaaatt aaaataaaat
     7861 aatcttgcaa ttattgacat tataagacag aataactgta aaaacatatt ttaaaatata
     7921 acaactatat aaaagagaat agacataatt aagaaaattc agaaaaaata aaataaaaat
     7981 aattgacaaa gagaataata tttgtatata ataatatgta atattaaaga ctgagaagaa
     8041 gaggagtaag taaatactac taaaagagag gaaaattcac tggctgtaag attttctaag
     8101 tataagattt actgaatgta gctttggagt ttctaaactg aactataagt aagtttagac
     8161 ggttagaacc gttaaattct ttgagagtca aagttgataa aataacatta accaataatt
     8221 taattatatg ttaatgtatt ttaagctttg gaattaaggt ggtaacgcga gcttttcgtc
     8281 ctttttaaag aggatgaaga gctctttttt atttctaaag atatttaaaa aatttattta
     8341 taaaatacag gaggcaggac aatggaaaat acgaatttat caaaaactta taacccaaaa
     8401 gattttgagg ctaggctata taaaaaatgg atggatgaag ggtattttaa atctaaacca
     8461 aatccagata aaaaaccatt tacaataatg atgccaccac caaatataac agggcaattg
     8521 catatgggac acgctcttga ccatacactt caagatatat taatcagatg gaaacgtatg
     8581 gatggatatg aagctttttg gcttccagga actgaccatg cttctatagc aacagaagtt
     8641 aaagttgttg aaagaataaa aaaacaagaa ggcaagacaa agtatgaaat aggtagagaa
     8701 gaatttttaa agagagcctg ggaatggaaa gatgaatttg gaggaaaaat atctaatcag
     8761 cttaaacaac taggtgattc ttgtgattgg gataaagaaa gatttactat ggatgaaggg
     8821 tgtaatgaag cagttataga attttttgta agcctatatg aaaaaggtca catatacaga
     8881 ggaaatagaa taataaactg gtgcccagat tgcaaaacta ctttatcaga tgcagaagtt
     8941 gaacatgaag aacacgacgg aaacttttat catataaagt acccactaaa agatagtgaa
     9001 gactttttag aaatagctac aactagacct gagacaatga taggagatac tggtatagca
     9061 gtaaatccag aagatgatag atataaacat ttaataggaa aaacagcaat acttccatta
     9121 gtaggaagag aacttccaat agttgcagat agttatgttg atttagagtt tggaactggt
     9181 gcagttaaga tgactccagc acatgaccct aatgattttg aagtaggatt aagacataat
     9241 cttgagcagt taaatactat gaatgaagat ggaactatga atgaagtttg tggaaaatat
     9301 gaaggtatgg atagatttga gtgtagaaaa gctatcgtag cagacttaaa agaacaaggt
     9361 tacctaatta agataaaaga gcataatcat aatgtaggaa cttgttatag atgccataca
     9421 gtagttgagc ctagattatc agagcaatgg tttgttaaga tggaagaact tgcaaaacca
     9481 gctatagata ttcttaaaaa aggagaatta gaatttgttc cagataaatt tgataaaact
     9541 tatttacaat ggctagaaaa tataagagat tggtgtatat caagacaatt atggtggggt
     9601 catcaaatac cagcttatta ttgtcaagag tgtggagaaa tagtagttgc tagaaaaatg
     9661 ccagataagt gtcctaaatg tggaagcact cattttaaac aagatgaaga tgccttagat
     9721 acttggttca gttctgcatt atggcctttc tctactctag gatggccaaa taagactgaa
     9781 gctttagatt attattatcc aacaagtgta cttgttacag gatacgatat aatattcttc
     9841 tgggtagtta gaatggcatt tgcaggtatg ttctgtatga atgaaaagcc atttgaccat
     9901 gttttggttc atggattagt aagagattct caaggtagaa aaatgagtaa atctttagga
     9961 aatggtatcg acccattgga gataatcgag caatatggag ctgatgccct aagatttaca
    10021 ttaacaactg gaaattcccc aggaaatgat atgagattct atatggaaag agtagaattt
    10081 gctagaaact ttgcaaataa gttgtggaat gcatcaagat ttgtatttat gaatattgat
    10141 gaagatataa ttaaaaacat gactagagaa agtgttaaag aggacttaac tctagctgat
    10201 aaatggataa tatcaagagc aaataatatt gtaaaagaag caactaataa catggataag
    10261 tttgatttag gaatagcact tcaaaagata tacgatttta cttggtcaga atactgtgac
    10321 tggtatattg aaatggttaa acctagatta tatggggaag atgcaaatgc taaatctgca
    10381 gcattatata cattaactta tgttcttgaa aagatattaa aattattaca tccatatatg
    10441 ccatttataa cagaggaaat atatactcat cttcctactg ttgaaggatg tataatagta
    10501 tctgaatggc caaaatataa tgaagaagat aacatggctg aagaagaaga tatgatgaac
    10561 ttattgatgg aaggtataag aagtataaga aatgtgagag cagaaatgaa tgtaccacct
    10621 tctaagaaag ctaaattgat aataatccca agtgaagaaa aaatagaagc tattgagctt
    10681 ggtaaagact attttataac tttagcatct gcttcaaatg tagagatagc aaaagataaa
    10741 tctaatgttc cagaagatgc agttggagta gttattgatg gtgttgaaat atttatacct
    10801 cttaatgaat tagttgattt tgaaaaagaa attgagagat tatctaaaga aaagaaaaag
    10861 ttagaaggcg aaataaagag agttaatgga aagcttgcaa atcaaggttt cttagcaaaa
    10921 gctcctgaaa gtttaattga agaagaaaaa gcaaaaaaag aaaaatttga agagatgatt
    10981 aaatctgttg aggaaagatt aacaaattta gaatctaaaa taaaataaat ataagaatta
    11041 gtaaaaacat acaaaaagta tatattctat actttttgta tgt
//
LOCUS       DAEPHU010000105        10950 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 01A10CD0081
            SAMN05941466-rid12468953.denovo.105, whole genome shotgun sequence.
ACCESSION   DAEPHU010000105 DAEPHU010000000
VERSION     DAEPHU010000105.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941466
            Sequence Read Archive: SRR6291087
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 10950)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10950)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068158.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 22:43:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,892
            CDSs (total)                      :: 3,805
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 87
            rRNAs                             :: 8, 1, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 55
            CDSs (without protein)            :: 55
            Pseudo Genes (ambiguous residues) :: 0 of 55
            Pseudo Genes (frameshifted)       :: 21 of 55
            Pseudo Genes (incomplete)         :: 28 of 55
            Pseudo Genes (internal stop)      :: 16 of 55
            Pseudo Genes (multiple problems)  :: 8 of 55
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10950
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941466-rid12468953.denovo.105"
                     /strain="01A10CD0081"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            complement(101..433)
                     /locus_tag="KR231_003392"
     CDS             complement(101..433)
                     /locus_tag="KR231_003392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxymuconolactone decarboxylase family
                     protein"
                     /protein_id="HBH0005724.1"
                     /translation="MNTREMKEYRGFYNKKLSETDEFFRVFGSLDDKTYSEGAISKKN
                     KELMGLAISILSRCDECICYHIEGCINSGASKDEIIEAIKIGVIGGGSITYPNARFAI
                     KILEEFNI"
     gene            complement(677..1318)
                     /locus_tag="KR231_003393"
     CDS             complement(677..1318)
                     /locus_tag="KR231_003393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SdpI family protein"
                     /protein_id="HBH0005725.1"
                     /translation="MKKAINKQFILSTLICFIPFIVSIYFYNRLPNEVAIHFDNYGNP
                     DNYAPKVIAAFGVPLLMLCIHLYTWFRLENEPKKANFSNVIQNLSKWGVAILSVIIQI
                     MMVLYSTGVSLESNFYTGLILGIIVILFGNYLPKCKRNYSVGIILPWTLNDEDNWNKT
                     HHLAGWIWLIGGILLIINAFINIPFYNIFVIFVIVILPFVYSYLMYKISGKNN"
     gene            complement(1299..1592)
                     /locus_tag="KR231_003394"
     CDS             complement(1299..1592)
                     /locus_tag="KR231_003394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HBH0005726.1"
                     /translation="MGFPETFKALSDPIRREILVMLRENKMSAGEISEKFNMTNATIS
                     YHLSQLKKAGLIFETKYKNFIFYEINISVFEEVMLWFSQFMEKGEKDNEKSDK"
     gene            1985..2035
                     /locus_tag="KR231_003395"
     CDS             1985..2035
                     /locus_tag="KR231_003395"
                     /inference="COORDINATES: protein motif:HMM:NF024729.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0005727.1"
                     /translation="MTEYIYYYNNKRIKKN"
     gene            complement(2561..3313)
                     /locus_tag="KR231_003396"
     CDS             complement(2561..3313)
                     /locus_tag="KR231_003396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TSUP family transporter"
                     /protein_id="HBH0005728.1"
                     /translation="MFSVIFLCIGGFLAAFVDSIAGGGGLISMPVLMAIGVPVHLAIG
                     TNKFAASAGCISSAYRYAKSGKINNNLLKKLVPFTIIGSVLGVRCVLSISEEILNVLV
                     VAMILIVAIYTFISKNLGQEDNFEAVNKKNLRLGMLMALIMGFYDGFFGPGTGTFLTF
                     GFIKIYGYDFLHASANTKILNLTSNITSLLLFMINGQVDYKIAIVFALVMIMGAYVGA
                     KVAIKKGSKMIKPIFLVMALFMVVKLVYQTLV"
     gene            complement(3372..5027)
                     /locus_tag="KR231_003397"
     CDS             complement(3372..5027)
                     /locus_tag="KR231_003397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBH0005729.1"
                     /translation="MVDFIESNNEVQKFDWGEVMWIHEPSKTQFNRLSAGIVRFFPGN
                     CQEKHFHLSEEQLLYVIQGEGIQIIDGKKVNIKETSIVYCPPYSEHEIINTGKIDLVI
                     LITYVPHKFSSLRQIPIVFSENNIQELVNVNIIENLANQISNILKLRISVYDLKYKEI
                     FETKKENKFCDICKNIKPCTKKLVKSINNDNFEKVYHCEYGVSSLEIPIVLEENIVGY
                     IECGNFIVYKSIYIDKNLSELSSSSGIDIKYINKIYNEFPLNPKSRLYVLKENLLMMS
                     EFIQEIAKRNFFENQLSIKDEEILKSRKENIRLEEALKKANSRLLEEEYIINPIDMFN
                     NSSKEYPFELELYIEKEIKNMNLEGVYNLIDTNKLRYNDVRDTIQEMIFVLSRTVLRD
                     LEDLKLISYLRNKYNKKISLVNSDEDLWNVLFEFSKECIDKNRAFWRKDKGNLIENIN
                     EYIKKYYKENINLNSISDVFFISPNYLSSIFNERNKVSITEYINLLRIEESKKYLLDR
                     SMSVSDICKKVGFNNSSYFSQIFKKFNSITPNEYRKNMLDNKY"
     gene            complement(6299..7378)
                     /locus_tag="KR231_003398"
     CDS             complement(6299..7378)
                     /locus_tag="KR231_003398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HBH0005730.1"
                     /translation="MILITLCILVAVFVLAFAGLRLIAPTIIRTSHKIEAPGIDRMEM
                     VEIGGIQQALYIRGQNADNPIILWVHGGPGNSMMPFLHLYQYEWENDFTVVNWDQRNV
                     GKTYFANDPAAVLQTMSAERVLQDVHEVTAYLKQEFNKEKIILIGHSWGTVLGTMAVQ
                     TYPEDYSAYIGIAQTVNMVDNERVGYEKTLEMVKAAGKQKDIKALEAIAPYPPAKYGP
                     SYLAALMTVRTYQSKYGLSINMDLGNIISILATPYYSLRELKNTAIVNPNAIDNQGDV
                     LRFLVEEADIRNYGVDYQVPVYYIMGENDYNSPYLPAKKFFDEIVAPDKQIFFIPDAD
                     HLPFLSKKAEFDCVLLEEIAPKLAK"
     gene            complement(7462..8118)
                     /locus_tag="KR231_003399"
     CDS             complement(7462..8118)
                     /locus_tag="KR231_003399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBH0005731.1"
                     /translation="MTRKNNPKQAIENIITISAKLFAEKGYDKTSMQNIVDASGMSKG
                     GIFHHFSSKEDIFNVVMERRFEQIIETVNQWLGEMHGLTAKEKLRSLVRRHLTDEVIK
                     ESSNMITSAIESPHIILAFTQDNLKKLAPILANVLREGIEDRSIITEFPDECAEVILL
                     LFNFWCDTDVFQGDFPTLRKRFQFLQFLMRQIGVDILEDEIIESINIFYERKPMGQVE
                     "
     gene            8440..8646
                     /locus_tag="KR231_003400"
     CDS             8440..8646
                     /locus_tag="KR231_003400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0005732.1"
                     /translation="MISHAAEICKKYKMPFIIFPTIEKKSIEEWVNIGANMLCFAQDT
                     TFITYVINQLLSFYNEIVPIQKQH"
     gene            complement(8799..9227)
                     /locus_tag="KR231_003401"
     CDS             complement(8799..9227)
                     /locus_tag="KR231_003401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin"
                     /protein_id="HBH0005733.1"
                     /translation="MSKIYIVYWSGTGNTEKMANFVAEGVKLKGKTPEVLDVSLLKPS
                     DLKEEDKFALGCPSMGAEQLEEGYMEPFVSELESMVSGKQIGLFGSYGWGNCEWMRDW
                     EERMQNAGATIIGGEGITAMEDPNEEAKDECIELGKTLAE"
     gene            complement(9703..10641)
                     /locus_tag="KR231_003402"
     CDS             complement(9703..10641)
                     /locus_tag="KR231_003402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S8 family peptidase"
                     /protein_id="HBH0005734.1"
                     /translation="MNKRMKLIPYEINENLRGAKNKFPYGIKQMNARGMWDEGYTGKN
                     IVVGIIDTGCDISHPLLKGKIIGGANFSDDSNGNKNIYEDFNGHGTHVAGIIAASNYN
                     NEVMGVAPDCKLLIAKALNKDGTGTYQSIINAINFAVNNKVDIISMSLGGNKDDKNLK
                     NAVMQAVKNNISVVCAAGNNGDGDSSTSEYSYPASYAEVIEVGAINENYLVEKFSNSN
                     TTIDLVAPGRNIISTYMDNKLAIMSGTSMSAPYVSGSLALIKEWAREEFERDLDEAEL
                     YAQLIKCTRALGIPRTEQGNGYLYLNLYKYKNNSKR"
BASE COUNT         3650 a         1931 c         1148 g         4221 t
ORIGIN      
        1 tctaaaaact taataagaag tgaacttaga aaataaagct taatttcaaa ggcttaaata
       61 gactattatt attagtctaa ataaactacg tgtatcaaaa ttatatatta aattcttcta
      121 aaatttttat tgcaaatctt gcgtttggat atgtaataga ccctccacca attacaccta
      181 tttttatagc ttctataatt tcatctttac ttgctccaga attaatacaa ccctcaatat
      241 gataacaaat acactcatca catcggctta aaattgaaat agctagtccc attaattcct
      301 tatttttttt acttatagcc ccttctgaat aagtcttatc atcaaggctt ccaaatactc
      361 taaaaaactc atctgtttca cttaattttt tattgtaaaa tcccctatat tctttcattt
      421 ctctagtatt catcttctac ctcctatttt tttcttataa gagtatcaca ctgtacttat
      481 attttcaata ttaaatacaa attttcattt tatgttcatt agcctaattt atattatttt
      541 ttgaaatctc aataagttat catataagta agattttttc agaactaaaa tagaaatctc
      601 agtaatttct ttattatcta tctcagttct gaaatatatt attcttatcc aaacattatt
      661 atagtgatta attatattag ttatttttac ctgaaatttt atacatcaaa taagaatata
      721 caaatggtag tattacaatt acaaagatta caaagatatt ataaaaagga atattaataa
      781 atgcattaat aattaataat attccaccaa taagccaaat ccatccagct aaatggtgtg
      841 tcttattcca attatcttca tcattaagag tccatggtaa aattattcct actgagtaat
      901 ttcgtttaca tttaggaaga tagtttccaa ataaaataac tattattcct aaaattaatc
      961 ctgtataaaa attagactcc aaactaactc ctgttgaata taaaaccatc attatttgta
     1021 taattactga aagtatagca actccccatt ttgataaatt ttgtataaca tttgaaaaat
     1081 tagctttctt aggctcattc tcaagtctaa accatgtata caaatggata catagcatta
     1141 acaatggtac accaaaagct gctataacct ttggagcata attatctgga tttccataat
     1201 tatcaaaatg aattgcaact tcatttggta atctattata aaaatatatt gatacaataa
     1261 atggtataaa acatattaaa gtagataaaa taaattgttt atttatcgct tttttcatta
     1321 tctttttctc ccttctccat aaattgcgaa aaccaaagca taacctcttc gaaaactgaa
     1381 atatttattt cgtagaaaat aaagttctta tactttgttt caaatatgag tcctgccttt
     1441 tttagttgag atagatgata agaaattgta gcattcgtca tattaaattt ttcactaatt
     1501 tctcctgctg acattttatt ctccctcaac ataaccaata tttctcttct tatagggtct
     1561 gaaagagctt tgaatgtttc tggaaacccc aacaccatca cctcgctatt tagaatttca
     1621 tctaaataga atataacata acatccattt tatttcaata actatttaga attttttcta
     1681 aatagttatt tctaaatatt tattgaaaat tttcatatta agattctcaa tttacttaag
     1741 tcgcttttat ttaatcttac tttatctaat ttttttaact taacaaaagt gtattgcacc
     1801 ataattgtta aagcaaaaac ctaatgactg aggtacttat atatataaca atacttttaa
     1861 ttttaaatta aaagtagcta aacccaattt aaaaagtagt taagtcctat ttaaatagaa
     1921 aagaatgaaa cgagaaatat actgtataaa agtacataaa aacatctact aattagatac
     1981 aactataaca gaatatattt attattataa taacaaaaga ataaaaaaaa attaatttag
     2041 catagccttg ttaaatatag atttgaatat gaatttaaag ttatgtaaaa ttaaaaatac
     2101 aggaatgaaa attccattcc tgtataaaat ctaacttttg agtctcagta caatcttatt
     2161 ttgagacaat cttttttgtt ttatattttc ttatatttaa aatataacgc atatcttatg
     2221 caacatattc atatttttct ttatattctt tcatcgcatc attccaagcg tcttgtactg
     2281 ttacacctct tttattagca attttttgtg ccagttcaat tatcttcata gctcttcttg
     2341 atatgttcat aaacattcct cctacaaatt accatatatt tcatatatat aaatcaaggt
     2401 tatattttta tgatatataa tccttctatt gtaagattac agtttatatg tgtattatat
     2461 atgaactata ttagaagata attagaattt ttataaagct atatgattag attaaatata
     2521 aaagctttac aattacttat aaatttaaaa agtctataaa ctaaactaat gtttgatata
     2581 ccaattttac gaccataaat aatgccatta ctaaaaatat tggttttatc atctttgaac
     2641 ctttctttat agcaacttta gcacctacat aagctcccat tatcatcact aatgcaaaca
     2701 ctatagcaat tttataatct acttgaccat ttatcatgaa taataacaat gaagttatat
     2761 tacttgttaa gtttaatatt tttgtatttg cagaagcatg taaaaaatca tatccatata
     2821 tttttataaa tccaaaagtc aaaaaagttc ctgtacctgg accaaaaaaa ccatcataaa
     2881 aacccattat aagagccata agcatcccta gtcttaaatt tttcttatta acagcttcaa
     2941 aattatcttc ttgacctaaa tttttagaaa taaaggtgta aatagccact attaaaatca
     3001 tagccacaac caaaacattt aatatctctt cacttattga taatacacat ctcacaccta
     3061 gaacactacc aataatagta aatggtacta atttttttaa aaggttgtta ttaatttttc
     3121 cagactttgc atatctatag gcactactta tacatcctgc tgatgctgca aatttatttg
     3181 taccaatggc aagatgtact ggcactccaa ttgccataag aacaggcatg cttataagtc
     3241 ctcctcctcc tgctatagaa tctacaaaag cagctaaaaa cccccctata cataaaaaaa
     3301 taactgaaaa cataaaattc ctccatcatt ctctttcaat ttttcttaca atatatatta
     3361 tataatctta tttaatactt attatccagc atattctttc tatattcatt tggagttata
     3421 ctattaaact tcttaaatat ttgtgaaaaa taactactgt tattaaaacc tactttctta
     3481 caaatatcac taacactcat gcttctatct aacagatatt ttttagattc ttctatccta
     3541 agaagattta tatactcagt tattgaaact ttatttcttt cattaaaaat agaactcaaa
     3601 taatttggac ttataaaaaa aacatctgat atactattca aatttatatt ttctttataa
     3661 tattttttta tatattcgtt tatattttca attagatttc ctttatcttt tctccaaaat
     3721 gctctattct tatcaataca ctctttggaa aattcaaata atacattcca taaatcttca
     3781 tcactgttta caagtgatat ttttttatta tatttatttc ttaaataaga tataagtttt
     3841 aaatcctcta aatctctaag cactgttcta gacaatacaa atatcatttc ctgaatagta
     3901 tctctaacat cattatatct taatttgttt gtatctatta gattataaac accttctaaa
     3961 ttcatatttt taatttcttt ttcaatataa agttctaatt caaagggata ttcttttgaa
     4021 gaattattga acatatctat cggattaata atatactctt cttctaataa tctactattt
     4081 gcttttttaa gtgcctcttc aagtcttata ttttcttttc tactcttcaa tatctcctca
     4141 tcttttatac taagttgatt ttcaaaaaaa ttcctcttag ctatttcctg aataaattca
     4201 gacatcatta ataaattttc ttttaataca tataatctac ttttaggatt taatggaaat
     4261 tcattgtaaa ttttgtttat gtattttata tcaataccag aactacttga taattcagat
     4321 aaatttttat ctatataaat agacttatat actataaaat taccacattc tatatatcca
     4381 actatatttt cttctaatac tataggtatc tctaaactgg aaacaccata ctcacaatga
     4441 tacacttttt caaagttatc attatttatg cttttaacaa gttttttagt acacggtttt
     4501 atatttttac aaatatcgca aaatttattt tctttcttag tctcaaatat ttctttatac
     4561 tttaagtcat atacagatat tctaagcttc aatatattag atatttgatt tgcaagattt
     4621 tcaattatgt ttacattaac taactcctgt atattgtttt cagaaaatac tataggtatt
     4681 tgtctcaaac tcgaaaattt atgaggaaca taagtaatta atattactaa atcaatttta
     4741 ccagtgttta taatttcatg ttctgaatat ggtgggcaat aaactataga tgtttccttt
     4801 atattgacct ttttaccatc aattatttgt attccttctc cctgaatcac atataaaagc
     4861 tgttcttcac ttaaatgaaa atgcttttct tggcagtttc ccggaaaaaa tcttacaatt
     4921 ccagcactaa gtctattgaa ttgtgttttt gatggttcgt gtatccacat aacctctccc
     4981 caatcaaatt tttgtacttc attatttgac tcaataaaat ccaccataaa ctcacctcgt
     5041 agtttttgtc taaatatttt ttcttccctt cttatattaa aataatatca tcatcattaa
     5101 ctttcattac tataaaatca tcatactctt ttaatactcc tgtaatttta gttgcactta
     5161 gtttactaca attcagtttt ttaatatatt gataaattct ataattactt ttttattttg
     5221 taaaatcagt gttttcccaa aataattata tctataaatg aaagtatttt tactgcttac
     5281 atcaatatat gttatcataa ttttcctttt tattgcatat ataaataact gtatataaca
     5341 ttgtccaata ctatatagaa atacatctaa gaaagaatat tattaaattg ttccaattaa
     5401 tattattttt cttatagaaa taaaaaactg ttggattctt ttagaaaaat tattttttac
     5461 ataccttttt tgcttaaata gtctatcttc tcagctattt tgtatataca ctcttctagt
     5521 tcatgatttt attttaatat cttgcttata ttgctgaaat aattaaattc ttttatctat
     5581 catattgtct cttatatcac aaacatattg tttcttatat cacaaaaatg aaagcattct
     5641 tatatcttca atatataaac ctgctttttt taatcttgta ataaatatag gatactctat
     5701 attctcttcc tagaaataac taataccact tatttttcta tcatatagaa agtaataaat
     5761 ctttttctta ataaaattca atagtaagtg gaataaaatt ttatatgaat aagaacatta
     5821 taaaaatact ttatacaata gtcaataaaa gatattagct tcaaattgtg ttgaagttgt
     5881 attatttaaa gtggaaaagc aaataaaaaa gaaataatgg tataagtaga aaaatatact
     5941 taaaacaagg cgaagcctct cttgtatcta aatcaagtag agaattaaat ctaaaaaaga
     6001 aaataaatat aaaagatgac tcctgtacat tacaagaatc atcttatggt ttcataatca
     6061 ctccatggtt tttaactgtc tgatataaag gtctcagttc actcatagca tgaccacctt
     6121 ttccgattgc tgaccccgtc acttatggac aaaatgtcca taagtgatag tcctctctta
     6181 aaaccctcta aatagatata tctcaagcac ctcattgaaa ccagttgctg gaaacaaact
     6241 gaagcgttct ggaatagtaa aagaaattgc caccatatcc acgttactgt cctagttgtt
     6301 actttgctaa cttcggagcg atttcctcta acaatacgca gtcaaattct gcctttttgc
     6361 taagaaatgg cagatggtct gcatctggta taaaaaaaat ctgtttgtct ggcgccacta
     6421 tttcatcaaa aaatttcttc gctggaagat aggggctatt atagtcattt tctcccatga
     6481 tgtagtatac agggacctga tagtcaactc cataatttct tatgtcagct tcttccacta
     6541 aaaaccgcaa tacatcacct tgattgtcaa tcgcatttgg attgacaatg gccgtatttt
     6601 ttaactctct caatgaataa tatggggttg ccagtatact gattatattg cccaaatcca
     6661 tatttataga aagcccatac ttgctttggt atgttcttac tgtcataaga gctgccaaat
     6721 agcttggacc atattttgct ggcggatatg gtgcaatagc ttccagcgcc ttgatatctt
     6781 tttgcttccc tgcagctttc accatttcaa gtgtcttttc atagcccacg cgctcattgt
     6841 ccaccatatt aacagtctgc gcaatcccaa tgtacgcgct gtaatcctcc ggataggttt
     6901 gcacagccat agttcccagc actgttcccc agctatgacc tataaggata attttctcct
     6961 tgttgaactc ttgcttcaaa tatgctgtca cctcatggac gtcttgcaga acacgctccg
     7021 cgctcatggt ctgcaaaact gctgccggat cgttcgcaaa gtatgttttg cctacgtttc
     7081 gctgatccca gttcaccaca gtaaaatcat tttcccactc atactggtac agatgtaaaa
     7141 atggcatcat tgaattacca ggacccccat gaacccaaag gatgatgggg ttgtctgcgt
     7201 tttgtccccg gatatataac gcctgctgta tgccgccgat ctccaccatt tccatgcggt
     7261 cgattccagg agcttctatt ttatggcttg tacgtataat cgtgggggct atcagacgca
     7321 aaccggcaaa cgccagaaca aaaacagcaa ctagtatgca aagtgtgatt aatatcattt
     7381 taagtacctt ctttcatgaa tttttttagc catagatatc tcctctaaca ttaaaaaaag
     7441 tatgttgcta ttttagtttt gttactctac ctgtcccatt ggtttccttt cataaaaaat
     7501 attaattgat tctataatct catcttccag gatatcaact cctatttgtc tcataagaaa
     7561 ctgtaagaat tgaaaccgtt tacgaagtgt aggaaagtcc ccctgaaata catctgtatc
     7621 acaccaaaag ttaaagagca gcaaaattac ctctgcgcat tcatctggga actctgtgat
     7681 gatgcttcta tcctctatgc cttctcgtaa aacatttgct aatattggtg ctagtttttt
     7741 caaattatcc tgtgtaaatg ccagtatgat atgcggactt tctatcgcgc ttgtaatcat
     7801 gttactagat tcttttatca cctcatccgt taaatgccgc ctaactaaac ttctaagctt
     7861 ctcttttgct gtaagtccat gcatttcacc gagccattga tttactgtct ctattatctg
     7921 ttcaaagcgc ctttccatga ccacattaaa aatatcttct tttgaactga agtgatgaaa
     7981 aattccgccc tttgacattc ccgaagcatc aacaatattt tgcatacttg ttttgtcgta
     8041 tcctttttca gcaaacaact ttgcagaaat ggtaatgata ttttcaatag cttgctttgg
     8101 attgttcttt ctagtcatta tataactcct tcttattaaa aaccgactgt tggtttttat
     8161 tatataagct attcctgctt ctgtcaagta acattgtgtt tatggcaaaa caataaggtt
     8221 tggtggttag acaggtatta attagactaa tgcgactttc ccctagatgg aacccttggt
     8281 aaatttgcaa tctttaccgg ctttgattat atctgtaagc aaggcaggta tggccacgcc
     8341 tgccctgttt gaccctcgga tattcattcc tatccctcct ctccttagcc attacaccaa
     8401 aacgccgctc attgtctcca atggcggcgt tttaaagata tgatttctca tgctgctgaa
     8461 atatgcaaaa aatataagat gccctttatt atttttccta caatagaaaa gaaaagtatt
     8521 gaagaatggg ttaatattgg agcaaatatg ctttgttttg cacaagatac tacctttatc
     8581 acttatgtta tcaatcaatt attatctttt tataatgaga ttgtaccaat tcaaaaacaa
     8641 cattaaatta taaatctaat tttatattaa aagagactaa tattttatct atctctatta
     8701 aggatatttt cttatgtatc ataatattag tctctcttat tattatatac tgctatcatc
     8761 attagttgtt atttatacta tttttataat atacaaattt attcagctaa cgttttgcct
     8821 aattctatac actcatcttt tgcttcttca tttgggtctt ccattgctgt aattccttct
     8881 ccaccaataa ttgtagcacc agcattttgc atacgttctt cccagtctct catccattca
     8941 caatttcccc atccatatga accaaataat ccaatctgtt tacctgatac catagattct
     9001 aattctgaaa caaatggctc catatacccc tcttctagtt gctctgctcc catagatggg
     9061 caacctaatg caaatttatc ttcttctttt aaatcacttg gtttcagtaa gctcacatct
     9121 aaaacttctg gtgtcttacc ttttaacttc acaccttcag ccacaaaatt tgccattttt
     9181 tcagtatttc ctgttccact ccaataaaca atatatattt tactcatttt tacctcctgt
     9241 agtatttttt aattaatcaa tagttagtta tagctaacta acatctaaaa aacaaaagat
     9301 ttctttatct gaaatctctt tatttttcta aatatagaat atcatagttg atattgaaat
     9361 tcaatactta ttgataatat ttatcattta tattttatat tcattttata atatcaaaac
     9421 actgtatcgt atttctaatc tttcatagaa aaatttctaa cttatagtac ttttgcatct
     9481 cttataaatc ttttatatgt ataagtacat agaaaaacac accttttcca gatgtgctat
     9541 ctataatatc gtatatttat ttttcaattc taactagcta atatgtttat aaattttatc
     9601 acttaatacc tttatacatt gatgtaaaat cttacaccta agtaattttt attatttgtc
     9661 tcgactctat ataatatagc tattttatca tcaaatcaaa aattatcttt tactattatt
     9721 cttgtattta tagagattta aatataagta tccatttcct tgttccgttc taggtattcc
     9781 aagcgctctc gtacatttta ttaattgtgc atacagttca gcttcatcta aatctctttc
     9841 aaactcctct cttgcccatt ctttaattag tgctaatgag cctgatacgt atggtgcact
     9901 catactagta ccactcataa tagcaagttt attatccata taagttgata taatatttct
     9961 tcctggagct accaaatcta ttgtagtatt tgaattacta aacttttcaa ccaaatagtt
    10021 ctcatttatt gcacctactt ctattacctc agcataactg gctggataac tatactcact
    10081 tgtactagaa tcaccatctc cattattacc tgctgcacac actacagaaa tattattttt
    10141 tactgcttgc atgacagcat tttttaaatt cttatcatct ttgtttcccc caagagacat
    10201 agatataata tcaaccttgt tatttacagc aaagttaata gcattaatta tactttgata
    10261 tgttccggta ccatctttat ttaatgcttt tgctattaat aatttacaat ctggagctac
    10321 tcccataact tcattattat aattagatgc agctataata cccgccacat gagttccatg
    10381 accattaaaa tcctcatata tatttttatt tccattactg tcatcactaa aatttgcacc
    10441 accaattatt tttcctttta aaagaggatg agatatatca caacctgtat ctattatacc
    10501 aactacaata tttttaccag tataaccttc atcccacatt cccctagcat tcatttgttt
    10561 tattccatat gggaatttat tttttgcacc tcttagattt tcatttattt catatggaat
    10621 tagtttcatt cttttattca tcatatatcc tcctaaaaat tttattgctt ataaaaatca
    10681 tgaattttat tttataatag gtttataaat caaattaaaa cctatatcta cttatttata
    10741 tttatgatat attttttatt tttaggagtc atattttatt gtatataaaa taatatttag
    10801 ataactatat taaaaaatac atgtttgctt atatacaaaa cttactaaaa tatcttcaat
    10861 atttttgtat acaaacatta tattttttat ataaaaatct cataaaaatt ttgattatat
    10921 tttcataagt taacaaatgt gggtataata
//
LOCUS       DAEPHU010000106        10816 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 01A10CD0081
            SAMN05941466-rid12468953.denovo.106, whole genome shotgun sequence.
ACCESSION   DAEPHU010000106 DAEPHU010000000
VERSION     DAEPHU010000106.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941466
            Sequence Read Archive: SRR6291087
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 10816)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10816)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068158.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 22:43:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,892
            CDSs (total)                      :: 3,805
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 87
            rRNAs                             :: 8, 1, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 55
            CDSs (without protein)            :: 55
            Pseudo Genes (ambiguous residues) :: 0 of 55
            Pseudo Genes (frameshifted)       :: 21 of 55
            Pseudo Genes (incomplete)         :: 28 of 55
            Pseudo Genes (internal stop)      :: 16 of 55
            Pseudo Genes (multiple problems)  :: 8 of 55
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10816
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941466-rid12468953.denovo.106"
                     /strain="01A10CD0081"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            <1..762
                     /locus_tag="KR231_003403"
     CDS             <1..762
                     /locus_tag="KR231_003403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="capsid protein"
                     /protein_id="HBH0005735.1"
                     /translation="IEIPTISTTGRVDSNRDTIAVAQRNYDNAWEPKVLTNQRKWSTL
                     VHPADINQTNYVASIGNITKVYNEEQKFPEMDAYCISKIYADWTALGNTADTTVLTTA
                     NVLEVFDKLMEKMTEARVPENGRILYVTPVVNTLIKNAKEIQRTVNIKDAGTSLNRQT
                     TDIDTVKIIKVPSNLMKTAYDFTTGWKVGAGAKQIFMSLVHPSAIITPVSYQFSKLDE
                     PTAVTEGKFFYFEESFEDVFILNKKADAIQFVVEA"
     gene            781..1014
                     /locus_tag="KR231_003404"
     CDS             781..1014
                     /locus_tag="KR231_003404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0005736.1"
                     /translation="MPQVKKLNRILTIEECKIDDFLEMGYDLIDETGKAVKYGKSLSV
                     KDLIAENNILRSKVESLEEENKQLKEKNKLTKK"
     gene            1024..1425
                     /locus_tag="KR231_003405"
     CDS             1024..1425
                     /locus_tag="KR231_003405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0005737.1"
                     /translation="MENNIIDEIEKRLESFGYILKDGDKWLIGFVREKIENIIKLDCN
                     IKTMPIELKEIEVDMIVGEFLFTKKNMGQLDIESINFEAVEKSISEGDTKVDFAIGSG
                     SQTPEQRFDSLIAYLTTYGKNKILTFRCLRW"
     gene            1419..1766
                     /locus_tag="KR231_003406"
     CDS             1419..1766
                     /locus_tag="KR231_003406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015984843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0005738.1"
                     /translation="MVSKTRKAIEMLYRDKCTIVEYQPIKDPVTKRTNNKEVIVLENQ
                     PCKLSYKNIVSATEGKVAKLEQTIKLFISPDIEIKAGSKLIINDKEYVRSGESAIYPN
                     HQEIILELFKDKA"
     gene            1766..2056
                     /locus_tag="KR231_003407"
     CDS             1766..2056
                     /locus_tag="KR231_003407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HK97 gp10 family phage protein"
                     /protein_id="HBH0005739.1"
                     /translation="MARWGSVDFREFKRVCKKMEELTKIDLDKFCKDAARELAARLLG
                     KVIRRTPVDTGFLRQGWNGVAYARSLPVYKQGNNYIIEVVNPTEYALTQWGI"
     gene            2166..2972
                     /locus_tag="KR231_003408"
     CDS             2166..2972
                     /locus_tag="KR231_003408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0005740.1"
                     /translation="MAKFLDITGKKFGRLRVIKFSKEIKSGKRNRKYWLCKCDCGNFK
                     EIRTDSLTSGLVQSCGCLKKEQDKLNLTDKYQFKKKYKVQNKRLYSIWKGIISRCTDK
                     NNKRYNRYGERNIIVCDEWFCYDNFANWALSNGYSEKLTIDRINNEGNYESSNCRWVD
                     IKTQCRNRSTNILVKHEEKEITLIELSEKTGISYSCLRSRYSKGLVGNNLIEKVKIIE
                     ESRAKLSIEDVKEIRKKYSDGYTIKQLSEIYPVTYSSISNIVHRRTWKNI"
     gene            3321..3758
                     /locus_tag="KR231_003409"
     CDS             3321..3758
                     /locus_tag="KR231_003409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0005741.1"
                     /translation="MLNNIIDGISIKLDKTFGESYTIYSEDVEQGINEPCFFIVPLNP
                     SKVSYPSGRTLKKNSFDVHYFPKSNDKSFEIDEVAEMLLEELEYIEIDGDLVRGTNMN
                     FEIVDNVLHFFVDYNYFTIKNNDINKMDTVELFGGLKRGDNFE"
     gene            3751..3927
                     /locus_tag="KR231_003410"
     CDS             3751..3927
                     /locus_tag="KR231_003410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0005742.1"
                     /translation="MSKTLSKGTDYKFTKEQIVNSKKYINRKDLLNAILKENELYSFS
                     EVEEIINSFMKGVS"
     gene            3929..5239
                     /locus_tag="KR231_003411"
     CDS             3929..5239
                     /locus_tag="KR231_003411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail sheath family protein"
                     /protein_id="HBH0005743.1"
                     /translation="MALGGGTFVTQNKILPGSYINFISAKRATSSLSDRGIVAIPLEL
                     DWGIDEDVFQVTSDDFEKYSVKYFGYDYTHEKLKGLRDLFKNIRLGYFYKLNKGVKAS
                     CTIATAKYSGIRGNDLKVTVTTNIDDNAKFDVVTLLDNKKVDTQIAKVITDLQDNDYI
                     TWKKDATLEASAGLVFTGGTNGEAVTGAEYQAFLDKIESYSFNALGCLATTTEIKSLF
                     VEFTKRMRDKVGAKFQTVLYKKSDADYEGVVSVENKIKDIGLVESSLIYWAAGVIAGC
                     DINKSNTNKKYDGEFDVDVNYTQIQLEEALKTGKFIFHKVGDEVHVLEDINTFVSFTD
                     DKNDDFSSNQSVRVLDQIANDIATLFNEKYLGKVPNDKAGRISFWNDVVKHHKELENI
                     RAIEDFKTDDVSVELGNDKKTVIVSDAVKVINAMSKLYMTVSVN"
     gene            5256..5726
                     /locus_tag="KR231_003412"
     CDS             5256..5726
                     /locus_tag="KR231_003412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail tube protein"
                     /protein_id="HBH0005744.1"
                     /translation="MAQTINAKDTVSAKKAECFITIEGKRYNFMQAIDLEAKMEKNKS
                     EVPILGRTTKGNKTTGSTNTGSATFHYNTSIFRELLYRYKETGEDIYFDIQVTNEDPT
                     SAVGRQTVVLKDCNMDSGIITKFDADGEYLDEDMDFTFEDWELVEKFNLLAGME"
     gene            5798..6238
                     /locus_tag="KR231_003413"
     CDS             5798..6238
                     /locus_tag="KR231_003413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HBH0005745.1"
                     /translation="MSNLSAFLSQNAIKVDNVKYVASNRFLDKEGKPVEWELKVLSSE
                     EDEALRRKCTKRVKVIGNNGKHTGQYTSEIDYNSYVAELCVASTVFPDLKDAELQNSY
                     GVMGEAQLLKTMLTAGEYVNYTVKVNEVNGFDTSFEDKVEEAKN"
     gene            6579..6740
                     /locus_tag="KR231_003414"
     CDS             6579..6740
                     /locus_tag="KR231_003414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0005746.1"
                     /translation="MNNFLLNVIAGVIASLIFCLICKVFLKVKSHSTRGKSKSGWEFD
                     FKIKFHKFK"
     repeat_region   7479..7835
                     /inference="COORDINATES: alignment:crt:1.2"
                     /inference="COORDINATES: alignment:pilercr:v1.02"
                     /rpt_family="CRISPR"
                     /rpt_type=direct
                     /rpt_unit_range=7479..7507
                     /rpt_unit_seq="gttttagattaactatatggaatgtaaat"
     gene            7997..8185
                     /locus_tag="KR231_003415"
     CDS             7997..8185
                     /locus_tag="KR231_003415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0005747.1"
                     /translation="MKIITDSSRADYFKQRRQNKKTFSVLLDREKVEKIEEHLKKQNK
                     TKTIWLEEKINEELEKEE"
     gene            8304..9170
                     /locus_tag="KR231_003416"
     CDS             8304..9170
                     /locus_tag="KR231_003416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage repressor protein"
                     /protein_id="HBH0005748.1"
                     /translation="MENLIVKEFNGSQIYTFMWKEKSCWIANQIVGLFDYADVSKTIQ
                     DCIKAEDFEIEQEYDVLKGNEFNDFVTTLNVVANNIISNKARSITIFYEDGLYGFLQY
                     TDKPIGVQFRKWLRREVLPSIRQTGAYITNNADPQALRDKANEIESLDTVNKTIEILT
                     PFLDNAGIDEKAKLLTAKTIYKKAGIELPLEIEEKEHFFDTVQIATKLNVYSKSNKPA
                     FHAIGEIIKKLDIQDNEKLVVLESKRGWSGSVNKYSQSVIDKVRNWIEENNRPTKIAG
                     EKKNYHVVYKIE"
     gene            9223..9378
                     /locus_tag="KR231_003417"
     CDS             9223..9378
                     /locus_tag="KR231_003417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0005749.1"
                     /translation="MHENLLDIDRIELIKELGNIFEKMKNENPDEFYRFVSLVKEECR
                     KKEEKNK"
     gene            complement(9797..10009)
                     /locus_tag="KR231_003418"
     CDS             complement(9797..10009)
                     /locus_tag="KR231_003418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010249169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBH0005750.1"
                     /translation="MSIKFFKLIDLLNRRGITKEELRLKIGASSTTIAKLSSNKNVSL
                     DVIDKICKALNCQPGDIMEYEDDEKL"
     gene            10284..>10816
                     /locus_tag="KR231_003419"
     CDS             10284..>10816
                     /locus_tag="KR231_003419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012103644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ORF6N domain-containing protein"
                     /protein_id="HBH0005751.1"
                     /translation="MNNLVLINNQELQVKEFNNQRVVTFKEIDQVHERTEGTAKRNFS
                     ENRKHFIENEDFFFVKASDFEKYGNRTLEIPNRGLTLITETGYLMLVKSFTDDLAWKV
                     QRQLVNSYFRVKEEIKTLEAVNESIKLITPFFEDLKIDKSMQFLVAKTFFKKAGVDIP
                     LEIEEKEHFYDTKQIAR"
BASE COUNT         4404 a         1105 c         2001 g         3306 t
ORIGIN      
        1 atagaaatac caactatatc tacaactgga agagtagatt caaacagaga tacaatagca
       61 gtagctcaaa gaaactatga taatgcttgg gaacctaagg tattaactaa tcaaaggaaa
      121 tggtctacat tggttcatcc agcagatata aaccaaacta attatgtggc ttcaataggc
      181 aatataacaa aagtatataa tgaggaacaa aagtttccag agatggatgc ttactgtata
      241 tctaaaatat atgctgattg gaccgcatta ggtaacacag cagatacaac tgttcttaca
      301 acagcaaacg tattagaagt atttgataag ttaatggaaa aaatgacaga agctagagta
      361 cctgaaaatg gaagaatatt gtatgttact ccagtagtaa atacacttat caaaaatgca
      421 aaagagatac aaagaacagt aaatataaag gatgcaggaa cttctcttaa tcgtcaaaca
      481 actgatattg acacagttaa aataattaaa gtaccatcta atctaatgaa aactgcatat
      541 gattttacaa ctggatggaa agtaggagca ggagctaaac aaatctttat gtccttagtt
      601 cacccaagtg caataattac acctgtttct tatcagttct ctaagttaga cgaaccaaca
      661 gcagttacag agggaaaatt cttctacttt gaagaaagtt ttgaggatgt atttatatta
      721 aataaaaaag ctgatgcaat acaatttgtt gttgaagcat agaaaaagga gtgatatata
      781 gtgccacaag taaaaaaact aaatagaata ctaaccatag aagaatgtaa aatagatgat
      841 ttcttagaga tgggatatga tttgatagat gaaactggta aggcagtaaa gtatggcaag
      901 tcattaagtg taaaagattt aatagctgaa aataatattt taaggtcaaa agttgagtct
      961 ttagaagaag aaaataagca gcttaaagag aaaaataaac ttactaaaaa gtaggtgaaa
     1021 attatggaaa ataatataat tgatgaaata gaaaaaagac ttgaaagttt tggatatata
     1081 ttaaaagatg gagataagtg gttaataggt tttgtaagag aaaaaataga aaatattatt
     1141 aaactagatt gtaatataaa aactatgcca attgaattga aagaaattga agttgatatg
     1201 atagttggag agttcttatt taccaagaaa aatatgggtc aattagatat agaaagcatt
     1261 aactttgaag ctgtagaaaa gtctatatca gaaggtgata caaaggtaga ttttgctata
     1321 ggaagtggtt ctcaaacacc agaacaacgc tttgatagct taatagctta tcttactact
     1381 tatggcaaga ataagatatt aacctttagg tgcttaagat ggtaagtaaa actagaaaag
     1441 caatagaaat gttatataga gataaatgta ctatagttga gtatcagcca attaaagacc
     1501 ctgtaacaaa acgaactaac aataaagaag tgattgtatt agaaaatcaa ccatgtaaac
     1561 tttcatataa aaatatagtt tctgctacag aagggaaagt agctaagcta gagcaaacta
     1621 ttaaactctt tatatctcca gatatagaaa ttaaagcagg ttcaaaactt attataaatg
     1681 ataaagagta tgtaagaagt ggagaatcag ctatatatcc aaatcatcaa gaaataatac
     1741 ttgagttatt taaggataaa gcataatggc tagatggggc agtgttgatt ttagagagtt
     1801 taaaagagtt tgtaaaaaga tggaggagct tacaaagatt gatttagata agttttgcaa
     1861 ggatgcagca agagaattag cagcacgatt acttgggaaa gtaattagaa gaacaccagt
     1921 tgatacagga ttcttacgac aaggatggaa tggagtggct tatgctaggt cgcttcctgt
     1981 gtataaacaa ggaaataatt atattataga ggttgttaat ccgactgaat atgccttaac
     2041 acaatggggc atataaaacc cagcaaaatc ggtaaacgct aagtgtaata gtgttacatt
     2101 ataaagtagg tagaatatgg acatagaata actcttgatt tataatgtat aaaagaggtg
     2161 attttatggc aaaattttta gatattacag gaaaaaaatt tggaaggcta agagtcatta
     2221 aattttctaa agagataaaa agtggtaaaa gaaatagaaa atattggtta tgtaagtgtg
     2281 attgtggaaa tttcaaagaa ataagaactg actctttaac tagtggctta gtacaatctt
     2341 gtggatgttt aaaaaaagaa caagataaat taaatttaac agacaaatac caatttaaaa
     2401 agaaatataa ggttcaaaat aaaagacttt acagtatatg gaagggtata atatctagat
     2461 gtacagataa aaataataaa agatacaata gatatggtga aaggaatata attgtgtgtg
     2521 atgaatggtt ttgctatgat aattttgcaa attgggcatt gagtaatgga tattcagaga
     2581 aacttacaat tgatagaata aataatgaag gaaattatga atcaagcaat tgtagatggg
     2641 tggatataaa gacacaatgt agaaataggt caacaaatat attagtaaag catgaagaaa
     2701 aagaaattac attgatagag ctttctgaaa aaacaggtat ttcatattct tgcttaagaa
     2761 gtagatattc taagggatta gtaggaaata atcttataga aaaagttaag attattgaag
     2821 aaagcagagc taagttatct attgaggatg taaaagaaat tagaaaaaag tattctgatg
     2881 gatatacaat aaaacaacta agtgaaatat atcctgtaac atattcatct atatcaaata
     2941 tagtccatag aagaacatgg aaaaatattt aattaattat atatgccaat accgaggaaa
     3001 acctatagat tgcgaatagg ctataggttt ccgtagagcg tagagagtga ataaatataa
     3061 tctctccaag agtgctgggc aactaaataa agtttatttt gttgatgatg tacgccgaac
     3121 ttataggaaa ctataagagc tagaggataa aaagccttta ggataacaaa atgcatatgt
     3181 tgaatatggc catagaacta aagatggaaa aggttgggtt aaaggacaac atttcttaac
     3241 aatttcagag atggaactac aaagccaagt tgataagatt atagagaaaa aactattaat
     3301 attgcttaaa ggagtatttg atgcttaata atataattga tggaatatct attaaattag
     3361 ataaaacatt tggagagagt tatacaattt atagtgaaga tgtggagcaa ggtataaatg
     3421 aaccttgttt ttttattgtt cctttaaatc caagcaaagt atcctatcca agtggcagga
     3481 cattaaaaaa gaactctttt gatgtacatt attttccaaa aagtaatgat aaatcatttg
     3541 aaatagatga ggtagctgag atgctactgg aggaattaga gtatatagaa attgatggag
     3601 atttagtcag aggtacaaat atgaactttg aaattgtaga taatgtactt catttctttg
     3661 ttgattataa ctactttact ataaaaaata atgatatcaa taagatggat acagtagagt
     3721 tattcggtgg tttgaagaga ggtgataatt ttgagtaaga cattaagtaa aggaaccgat
     3781 tacaagttta ctaaggagca gatagttaat tctaagaagt atataaatag aaaagactta
     3841 ttaaatgcaa ttttaaaaga aaatgagtta tattccttct cagaggtaga ggaaataata
     3901 aatagcttta tgaaaggagt gagttaattt ggcgttaggt ggaggaacat ttgtaacaca
     3961 gaataaaata ttaccaggta gctatataaa ttttatctca gctaagaggg caaccagttc
     4021 attatcggat agaggtattg ttgcaatacc tttagagtta gattggggca tagatgaaga
     4081 cgtatttcaa gtaaccagtg atgattttga gaagtattca gtgaagtatt ttggatatga
     4141 ttatactcat gagaagctga aaggtttgag agatttattc aaaaatataa ggttgggata
     4201 tttttataaa ttaaataaag gcgttaaagc cagttgtact atagccacag caaaatatag
     4261 tggtatcaga ggaaatgact taaaagtaac agttacaaca aatatagatg ataatgctaa
     4321 gtttgatgtt gtaacacttt tagataataa gaaggtagat actcaaatag caaaggttat
     4381 tacagactta caagacaatg actatatcac ttggaagaag gatgcaacac tagaagcaag
     4441 tgcaggactt gtatttactg gtggaactaa tggcgaagct gtgacaggag cagagtacca
     4501 agctttcttg gataaaatag aaagctatag ctttaatgct ttaggatgtt tggctacaac
     4561 aacagaaatt aaaagtttat ttgtagaatt tacaaagaga atgagagata aggtaggagc
     4621 taagtttcaa acagtactat ataagaaaag tgatgcagat tatgaaggtg tagtgtctgt
     4681 agaaaataag attaaagata ttggattagt agaatctagt ttaatttatt gggcggctgg
     4741 agttatagca ggatgcgata taaataaatc taatactaat aaaaagtatg atggtgagtt
     4801 tgatgttgat gttaattata cacaaataca acttgaagaa gctttaaaaa ctggtaaatt
     4861 tatattccac aaggtgggag atgaagttca tgtgttagag gatataaata cttttgtatc
     4921 atttacagat gataaaaatg acgatttttc aagtaaccaa agtgttagag tacttgacca
     4981 aattgctaat gatattgcaa ctttatttaa tgaaaagtat ttaggtaaag ttccgaatga
     5041 taaggcagga agaataagtt tctggaatga tgttgttaaa caccataaag aattagagaa
     5101 tataagggca atagaagatt ttaaaactga tgatgttagt gtagagcttg gaaatgataa
     5161 gaaaactgtc atagtatctg atgctgttaa ggtaataaat gctatgagta agctttatat
     5221 gactgtttca gttaattaga gaggagagtg ataatatggc tcaaacaata aatgctaaag
     5281 atacagttag tgcaaagaaa gctgaatgtt ttataactat agaaggtaaa agatataatt
     5341 ttatgcaagc tatagattta gaggctaaaa tggaaaaaaa taaaagtgaa gttccaattc
     5401 taggaagaac aacaaaggga aataaaacaa ctgggagtac aaatactgga agtgcaacat
     5461 ttcattataa tacttctatt tttagagaat tactttacag atataaagaa actggtgagg
     5521 atatttattt tgacatacaa gttacaaatg aagaccctac atctgctgta ggaagacaga
     5581 cagtagtact taaagattgt aatatggaca gtggaataat tactaaattt gatgctgatg
     5641 gtgagtattt agatgaagat atggatttca cttttgagga ttgggaatta gtagaaaaat
     5701 ttaatttatt ggcaggaatg gagtaaaata cacatttata aattatatat gtgtattttt
     5761 tatatgaaaa attaaaataa aaggagatta gaataatatg agtaatttaa gtgctttttt
     5821 aagtcaaaat gcaataaagg ttgataatgt aaaatatgta gcgagtaaca gatttttaga
     5881 taaagaaggg aaaccagttg aatgggaatt aaaagtttta tcatctgaag aagacgaagc
     5941 actaagaaga aagtgtacta aaagagtaaa agtgattggt aacaatggta agcatactgg
     6001 acaatataca agtgaaattg actacaatag ttatgtagct gaattatgtg tagcatctac
     6061 agtatttcca gatttaaagg atgccgaact ccaaaatagt tatggagtaa tgggagaagc
     6121 tcagttatta aagacaatgc ttacagcagg tgagtatgtc aattatacag taaaagtgaa
     6181 tgaagtcaat ggatttgata catcttttga ggataaagta gaagaagcaa aaaactaatc
     6241 agaggtggcg attttgatgc tagcatcact cattattgta ttcaaaaatt aaagtggaag
     6301 ccaagtgaat atatgaattt agaagttaat gagagagcgt tagcagccgc ctcaatactt
     6361 ataaagatag aagatgaaga ggaagcaatg aaagaagctg aaagagagag aaagagggga
     6421 cgaagaagat agcaaaataa aaaaataaat atagaatagg taaaatatgt aataattata
     6481 tgttataata tttttagcaa gaagatgtaa tctacaattt atagagtgga gttcatactg
     6541 ggataaaacc tacttcctaa tgaaaggagg tgggaagtat gaataacttt ttacttaatg
     6601 taatagctgg cgttattgct agtttaatat tttgcttaat ttgtaaagta tttctaaaag
     6661 taaaaagcca ctcaactcgt ggcaagagta aaagtggctg ggaatttgat tttaaaatca
     6721 agttccataa gttcaaatag attcatttaa ttatgaactt cactctaccg caaaatagat
     6781 tgtagttctt cttgctttta ttataccaca aattagaaaa aatattgttt atataaaata
     6841 aaaaataaaa atttttatta aaaaattgaa aacttgatta taaagcaatt aatttataaa
     6901 atatatataa ataagtaggt atttatttac ttgaatttca ttgtttatat aaaaaaaatg
     6961 gaaaaatatg taataattat atgttataat aattgtagca aggataataa tcgaaagtgc
     7021 gaagggtgat tattttcata ttaaacgcca aattccaaat aaggaaggag gtgaaattat
     7081 atgataggtt ttttattaag catactagct ggtgttatat cagcttatat ttatgacaaa
     7141 ataaaaaatc acccagacgc caataagggt gatttaaaaa aataattctt taaatcaatt
     7201 ttgatggaaa tagctactct tgtataaagt aaattatttc cttgctttta ttataccaca
     7261 aattggtaca gatattcaaa aataatattt ttatgatata ataaaaatat aaatagtttt
     7321 gcagtgagcg atatttgtta caaaatatgg tctaacactt gaaatacaag gcattgaggg
     7381 tgtgtgataa atgttatcaa ttgcactact catggttcac tgcaaatttg agagagatgc
     7441 gtatgtgtag gtattggaaa tgctaagttt attttggggt tttagattaa ctatatggaa
     7501 tgtaaattaa atatagcttc ttctccataa ctataagttg catgttttag attaactata
     7561 tggaatgtaa atccaaacga atttgtatta ctaaaatcat tccacaactg ttttagatta
     7621 actatatgga atgtaaatta gcttgatagt atccaccctc catggcattg tttgagtttt
     7681 agattaacta tatggaatgt aaattcagaa acaggaacat caaaaggagg tttaaaatct
     7741 ggttttagat taactatatg gaatgtaaat tgctgtgatt tcactaataa aacaattaat
     7801 aattgtgtta tagattaact atgtggagaa aaactaaata aacaaagaaa gcacttacaa
     7861 atatgtaggt gcttttgttt tgctcaaatt ggtcggttga gtgaaataat tagaaaaaat
     7921 tagtaaaaac tagtaaaaac tcttgaaaag tgtcgcgata caatgtataa ttatattatc
     7981 gcgatacaga aaagaggtga aaattattac tgatagcagt agagcagatt acttcaagca
     8041 gagacgacag aataagaaaa cttttagtgt tctactagat agagagaaag tagaaaaaat
     8101 tgaagaacat ttaaaaaagc agaacaagac taaaactatt tggcttgaag aaaagattaa
     8161 tgaagagtta gaaaaagagg aataaaaaat aagagacgtt ctccccgacc aaagattgaa
     8221 catcccttat tgacgtatat tatatacact aactatagta tacgtcattc cttaaaaaaa
     8281 ttcaattaag gagtgtaata gttatggaaa atttaatagt aaaagagttt aatggaagtc
     8341 aaatttatac ttttatgtgg aaagaaaaat cttgttggat agctaatcaa atagttggat
     8401 tattcgatta tgctgatgta tctaaaacaa tacaggattg cataaaagca gaagactttg
     8461 agattgaaca agagtatgat gtattgaaag gaaatgaatt taatgatttt gtaactactt
     8521 taaatgtagt cgcaaataat ataattagta ataaagctag aagtataact attttttatg
     8581 aagatggttt gtatggattt ttacaataca cagataaacc aattggtgta cagtttagaa
     8641 aatggcttag acgagaagtt ttaccaagca taagacaaac tggtgcatac ataacaaata
     8701 acgctgaccc tcaagcacta cgagacaagg caaatgaaat agaaagtcta gatacagtta
     8761 acaagactat agaaatacta acaccattct tagataatgc tggaatagat gaaaaagcaa
     8821 agttacttac agcaaagact atctacaaaa aggcaggaat agagttacct cttgaaatag
     8881 aagagaagga acatttcttt gatactgtac aaatagcaac taagttaaat gtttattcta
     8941 agtctaataa acctgcattt catgcaatag gtgaaattat taagaagtta gatatacaag
     9001 ataatgaaaa gttagtagta ctagagagta aaagaggttg gagtggaagt gttaataagt
     9061 attcacagag tgtaatagat aaagtgagaa attggataga ggagaataat agacctacta
     9121 agattgcagg tgagaagaag aattatcatg tagtttataa gattgagtaa atttataaga
     9181 ttgtattaaa taatttagtt tagttttggg gggattaata caatgcatga gaatttactt
     9241 gatatagata gaatagaact tatcaaagaa cttggaaata tctttgaaaa aatgaaaaat
     9301 gaaaatccgg atgaatttta tagatttgta agtttagtga aagaagagtg taggaaaaaa
     9361 gaagagaaaa ataaataaat agacaaataa agcacttgaa tattttactg tttcaagtgc
     9421 tttatgtagt aaaaaatgat ataatatagg taggagttat attaactaag tggtatgtaa
     9481 atgctgtatc ctttgcccct tttgctgcgt cactcaaggt ttttatatta acaatgtggt
     9541 atgtaaagtc gtttatcatt gctagcctcg cattcgtact ggtcaatttt atattaacta
     9601 agtggtatgt aaatcattca ctacaaaata tatattctaa tgtatcattc gttttatatt
     9661 aactatatgg tatgtaaaca atatatatag caaatctgtt atattaacta tgaagggttt
     9721 tatattaact atgtggactt aaaattaaat agaaaaaaga aagcacttac ttaaatagta
     9781 ggtgcttttg ttttgcttat aacttttcat catcttcata ttccataata tcacctggtt
     9841 ggcagtttaa agctttacat attttatcaa ttacatcaag tgaaacattt ttatttgaag
     9901 atagtttggc tattgtagta gaagaagctc ctattttgag tcttagttct tctttagtta
     9961 tacctcttct gtttagtaag tcaattagtt taaaaaattt tatagacatg ttaatacctc
    10021 ctatatattt atataatact atatatattt attaaagtaa agatatattt attaaaataa
    10081 ataaaaagta ttgacattat ttactaaata atgtattatt agagtataaa gataaagaaa
    10141 tctttataaa gataaagcaa taagggataa aataaggaat attctctctc gtcaaagttt
    10201 aaatattcct tatgacatat aactaatatg taatataatt atatgtcatt ccttaaaaaa
    10261 aatcaattaa ggagtgtatt tttatgaaca atttagtatt aattaacaac caagagttgc
    10321 aggtcaagga gtttaataat caaagagtag ttacatttaa agaaattgac caagtacatg
    10381 aaagaacaga aggtacagca aagagaaatt tctcagagaa tagaaaacat tttatagaga
    10441 acgaagattt cttttttgta aaagcaagtg attttgaaaa gtacggaaat cgtactttag
    10501 aaattcctaa tcgtggatta actttaataa ctgaaacagg ctatttgatg ttagtaaaat
    10561 cttttacaga tgacttagca tggaaagtac aaagacaatt agtaaatagt tattttagag
    10621 ttaaagaaga aataaaaaca ttagaagcag taaatgagtc aattaaatta ataactccat
    10681 tttttgaaga tttaaaaatt gataaaagta tgcaatttct tgttgctaaa acatttttca
    10741 aaaaagcagg agttgatatt ccacttgaaa ttgaagaaaa ggaacatttt tatgatacaa
    10801 aacaaattgc aagaaa
//
LOCUS       DAEPHU010000107        10272 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 01A10CD0081
            SAMN05941466-rid12468953.denovo.107, whole genome shotgun sequence.
ACCESSION   DAEPHU010000107 DAEPHU010000000
VERSION     DAEPHU010000107.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941466
            Sequence Read Archive: SRR6291087
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 10272)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10272)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068158.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 22:43:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,892
            CDSs (total)                      :: 3,805
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 87
            rRNAs                             :: 8, 1, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 55
            CDSs (without protein)            :: 55
            Pseudo Genes (ambiguous residues) :: 0 of 55
            Pseudo Genes (frameshifted)       :: 21 of 55
            Pseudo Genes (incomplete)         :: 28 of 55
            Pseudo Genes (internal stop)      :: 16 of 55
            Pseudo Genes (multiple problems)  :: 8 of 55
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10272
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941466-rid12468953.denovo.107"
                     /strain="01A10CD0081"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            122..739
                     /locus_tag="KR231_003420"
     CDS             122..739
                     /locus_tag="KR231_003420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF488 domain-containing protein"
                     /protein_id="HBH0005752.1"
                     /translation="MEIFAIGHSNYPYDKLINMIKKYDINCVVDIRETPYSKYNIQYN
                     KEAFNESLRNSGFLYIYMGKEFGAKRTNKDVYTQEGYADFEKVAKEDIFLNGIERLKK
                     GCQMGYRIVLLGAMQEPIRCHRSILVGKVLNKEGFDVKYIMHEGNLAYQEDIEESLLD
                     KYFSDRKQLSIDNLLGSALTREEMIQEGYKLANKEIGYRTEKLGK"
     gene            complement(896..1348)
                     /locus_tag="KR231_003421"
     CDS             complement(896..1348)
                     /locus_tag="KR231_003421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0005753.1"
                     /translation="MVNLNANNLNVNMVYPISSTAPIRFRRYTVSYLENMENIYLTIA
                     TYFDTLGLGTMNIDKVYGQWAWFTDNIYDLNLFVFVGNYPYQIAKNRYDTFVDILPVA
                     ITSIVNGDRIFLISNPCLLNSKITVRFISSHPTLNRTVDYGNIRDFIF"
     gene            1796..3154
                     /locus_tag="KR231_003422"
     CDS             1796..3154
                     /locus_tag="KR231_003422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HBH0005754.1"
                     /translation="MFIRKNVIKLAIPIMIEQTFVMLLGVFNTMMAGHIGEEAVSAVG
                     MVDSINNIFISVFAALSVGATVVVAQQIGKKDGEKVNETIKQALVSGVILSFTITILM
                     WVFRTGVINLFYGSAEELVKSNAKLYIEFTLFTYPFIATQQIANGLLRGCGDVKKPMY
                     VTMFMNIVNVTLGYILIYGIDLNPLGINLQTPSYGITGAAISIAIARIIGCIVIIRAL
                     FKGNEFISMGKIFPFKIDVETQKSIFNIGIPAGVEQLLFNAGKLIVQVFIVTMGTSAI
                     ASNAIGMSIASIINVIGNALALSATTLVGQYIGRGDIKGAKSTLLYLTKFATICLFIV
                     GAIFIPIAPWISSMYTQNASVIDISTQLIRSDCLAMVIWPISFVLSAGLKGAGDTRYT
                     MMTAVIGMWIFRIFTGYVLGVVLEFGVLGIWIGMYTDWLVRGTLYCLRLRGTKWLKHK
                     VA"
     gene            3427..3807
                     /locus_tag="KR231_003423"
     CDS             3427..3807
                     /locus_tag="KR231_003423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HBH0005755.1"
                     /translation="MINKIGKITLYVNNQEDAKLFWTEKLNFVVTYEKEMGPNMKWVE
                     VAPSKNEFTTFVLYDKNLMMRQNKEINVSHPSIILSTRDINGTYEQMANNEVEVGELM
                     EMPYGRMFSFKDQDGNDYLVREDK"
     gene            3932..4132
                     /locus_tag="KR231_003424"
     CDS             3932..4132
                     /locus_tag="KR231_003424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0005756.1"
                     /translation="MFKKMAVLKDIATKIGRKKAYELLEMVEGNDAFVAEVKIKKNGI
                     ESKKEEIMLKDNQKIILEYIEG"
     gene            4328..5056
                     /locus_tag="KR231_003425"
     CDS             4328..5056
                     /locus_tag="KR231_003425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBH0005757.1"
                     /translation="MLEIKNLSFNVESNNEELGIINDVSLSFERGKLIVITGPNGGGK
                     STIAKLIMGIEKATSGQIILDGEDITNLSITERAKKGIGYAFQQPPRIKGMTVENLLT
                     LAHGKPLSTDVCCQYLTDVGLCSKDYLNREVDNSLSGGEMKRIEIATLFARDLKVSIF
                     DEPEAGIDLWSFGKLNESFKKIHEESNQTIIIISHQERILELADEIIVLQDGSVKSHG
                     TKEAILPEIMCQVNSSCELMKDMN"
     gene            5078..5995
                     /locus_tag="KR231_003426"
     CDS             5078..5995
                     /locus_tag="KR231_003426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SufD family Fe-S cluster assembly protein"
                     /protein_id="HBH0005758.1"
                     /translation="MNKIDLNLLEKVAELRGTPLGAYNIRKNGQGVERHSTENVTIIP
                     KTDKPGIDIIVKPNTKGENVHIPVIVTETGVQDMVYNDFEIGENADVVIIAGCGIHNC
                     GCDDSEHNGIHRFFLRKGARLKYVEKHYGEGDGEGKRILNPVTIVNMDEDSYCEMETI
                     QIKGVDSTKREMDANLGKGAKIVVFEKLLTHGNQVAESNMKVILEGENSSAQVVSRTV
                     GQDNSKQKFNPCVIGDSLCSAHVQCDSIIMGNSQISAIPEIAANHPDALLVHEAAIGK
                     IAGDQILKMMTLGLTEEEAEQQILNCFLK"
     gene            6137..7321
                     /locus_tag="KR231_003427"
     CDS             6137..7321
                     /locus_tag="KR231_003427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase family protein"
                     /protein_id="HBH0005759.1"
                     /translation="MKNLLIRNGTIISPTDGIKFEKRDILVLHGKIYAIGLNLKEKIR
                     KEKLLTNKEFEIINADNMYISPGFIDVHTHCYKRKLPTGMDSDSIGIEKGSTVIFDAG
                     TAGPLNYYDFKKKYMDECKTEVYSFLNVTNEGLNILNESTSLDVINFDKVESVVEKNI
                     EKIKGIKVKASKFQSNESGIDIIKKSKQVAKKLNLPLVVYIGEYPSYIDEVMNILGKG
                     DVVTPVYGNSTNGILKESGTLRKSVINAKNRGVLFDVCHGLNQFDFKVFKKAIKQGLE
                     PDLISTDMHIKNMKDVNYSLLSVINKIMELGISLEKCIEKVTEYPTKIFDLHGNKGRI
                     KIGGEGDFTIFTMEECNDIIKDYNNNELVLNKKLRLQYTVKSWMKSSEVYRHGYENTI
                     IN"
     gene            7428..7616
                     /locus_tag="KR231_003428"
     CDS             7428..7616
                     /locus_tag="KR231_003428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferredoxin"
                     /protein_id="HBH0005760.1"
                     /translation="MKAFVDKDVCVACGACIGTCPDVFSMSDEGHSVAIEGEIPADLQ
                     DLCKEAEEGCPVSAITVK"
     gene            7766..8416
                     /locus_tag="KR231_003429"
     CDS             7766..8416
                     /locus_tag="KR231_003429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HBH0005761.1"
                     /translation="MKKNYEIVLFDLDGTLTDPKEGITKSIQYSLNSFGIKEDLENLD
                     QFIGPPLHDTFKEYYKFEDKKTKEAVEKYREYFADKGIFENKIYENIKEILEMLYKNG
                     KILLVATSKPTVFAETILRYFDIDRYFKYIAGSNLDGTRVNKNEVIQYVLDLCNVKDK
                     DKVIMVGDRKYDIIGAKKIGIDSIGVLYGYGSFEELSESEPTYIVENVESIKDILL"
     gene            8519..9457
                     /locus_tag="KR231_003430"
     CDS             8519..9457
                     /locus_tag="KR231_003430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HBH0005762.1"
                     /translation="MKSILIMGGSDFIGSALAKRLIKCGYQIDILTNGKKEIDYNGFK
                     EHLICDRKVRKDMENIITGRKYDYIYDMTAYTKEDVSNLIDFISMDNLKKYIVLSAGA
                     VYKDSGRNIKEENEKGENENWGKYGLNKKEAEDFIINSPIPYIIIRPTYIYGENNNLY
                     REYYFFEKIEKNEKIPVPKGKQVSNQFIYIGDLVKVLESIMKNPHVREAYNVTNPQLI
                     SWDDLIYTCGEIIGKEPIIKYVDMEKVEFRERTYFPFRNIDFNLDINKLIEHGLYIPN
                     VLLKEGLTATYKWFSANKPKMHDRKMNKVESVMQIV"
     gene            9483..>10272
                     /locus_tag="KR231_003431"
     CDS             9483..>10272
                     /locus_tag="KR231_003431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HBH0005763.1"
                     /translation="MNSKIKYFLKFFILIFILIFIYSVAIEPSLLIVKKYNISENGTL
                     IKSDTIESKSERIKVVQISDTQIGSFYSTKNLKKVANKINTLNPDIIVFTGDLIDYSN
                     KNPSVDEITTILSSMNARLGKFSVFGNHDYMYKLPRYYRQIMKNSNFNLLVNENKKIK
                     LKDDKYINILGVDEILNGNPNIKYLESQIDNKNFNLLLAHEPDLVDMLSKDTMNLVLS
                     GHSHGGQIRLPIKGALVTPPYGRKYTKGFYDINGNHLYVSSGLGS"
BASE COUNT         4162 a          988 c         1832 g         3290 t
ORIGIN      
        1 aaaatataca atatcaagaa aaaaagatat tgggtattta aagtaatact ttatttaatt
       61 ttaagtaaat cgggtatcta catatataga tactaatttc aaagaatagg agggtgttta
      121 tatggaaata ttcgcaatag gacattcaaa ttatccatat gataagctta ttaatatgat
      181 aaaaaaatat gacataaatt gtgtagttga cattagagaa actccatatt ctaaatataa
      241 tattcaatac aataaagagg catttaacga atctcttaga aattccggat ttttatatat
      301 atacatggga aaagaatttg gagctaaaag aactaataaa gatgtatata cgcaagaagg
      361 ttatgcagat tttgagaaag tagcaaaaga agatattttt ttaaacggaa tagaaagatt
      421 aaaaaagggt tgtcaaatgg gttataggat agttttatta ggagctatgc aagaacctat
      481 aagatgtcat agaagtatct tggtgggaaa agtattaaat aaagaaggtt ttgatgtaaa
      541 atatataatg catgaaggaa atttggcata tcaggaagat atagaggaat cattattgga
      601 taagtatttt agtgatagaa agcaactgag tattgacaat ttattaggga gtgcattaac
      661 gagagaagaa atgatacaag aaggttataa gctagctaat aaagaaatag gatatagaac
      721 tgagaaacta ggtaaataaa aatatacaag tagataaaat acagtactta tcttaagtaa
      781 aataatatta tgaatttata atagctaggc atgatgtgcc aattaaaaat attctagtta
      841 tttaataata tcattaaatt tagggtattt tttaatagca catcatgttg cagttttaaa
      901 aaataaaatc tctaatattg ccataatcaa ctgttctatt aagagtagga tgactagata
      961 taaatctaac tgtaattttt gaatttaaca aacaaggatt tgaaattaaa aatattctat
     1021 ctccattgac aatagaagta atagctactg gcaaaatatc tacaaatgta tcatatctgt
     1081 ttttagcaat ttgataagga taatttccta caaaaacaaa tagatttaaa tcatatatat
     1141 tatcagtaaa ccaagcccat tgaccataaa ctttgtcgat attcattgtg cctaaaccaa
     1201 gtgtatcaaa gtatgttgct atagttaaat aaatattttc catgttttct aaatatgaaa
     1261 cagtatatct tctgaaacgt atgggtgctg tggaagaaat aggataaacc atatttacat
     1321 ttagattatt tgcatttaaa ttaaccaaag tatcacatcc taaaattagt ctataaaata
     1381 caatatttaa atggatgcga ttttgttaca tctaaagtgt aatattttat atattgaaaa
     1441 agtggtaaaa gtttggatga ttaaataata ttataaaaaa tatataaaat gtacttattg
     1501 ttattgctac acgatagtga tacaatatta acgaaatata gctactttta ataataacgg
     1561 aaaatattta tattaaatta ataaatattt taaatgtggt atccataaaa aataataaac
     1621 ataagataat tataaagata tactgtgttc aaatgatatt aaacaagatt tatattattt
     1681 gaaagcagta tattataatg cgaacaatac aattctaaac tttgcattgt caatttacag
     1741 ttcgataaac taattaaaaa ttaaatttat ataaagaggg aaaagaggaa tagggatgtt
     1801 tataaggaaa aatgttataa agttagcaat tcctataatg atagagcaga cgtttgtcat
     1861 gcttttagga gtatttaata caatgatggc aggtcatatt ggggaagaag ctgtatctgc
     1921 agttggaatg gttgattcaa taaacaatat atttatatct gtatttgctg cactatctgt
     1981 tggagctact gttgttgtag ctcaacaaat aggaaaaaaa gatggtgaaa aggtgaatga
     2041 aactattaag caggctctag tgtctggagt aatattatcc tttacaataa caatattgat
     2101 gtgggttttt agaactggtg taattaattt attttatggt tccgcagaag aattggtaaa
     2161 atcaaatgca aaattataca tagagtttac attatttacg tatccattta ttgcgacaca
     2221 acaaatagca aatggtcttt taagagggtg tggagatgta aagaaaccta tgtatgtgac
     2281 tatgtttatg aatatagtaa atgtaacatt aggatatata cttatatatg gtattgattt
     2341 aaatcctcta ggaataaatt tgcaaacacc atcctatggc ataacaggtg cagctatatc
     2401 tattgctata gctagaataa ttggatgtat agtaattata agagctttat ttaaaggaaa
     2461 cgaatttata tctatgggta aaatatttcc atttaagatt gatgttgaaa ctcaaaagtc
     2521 tatatttaat ataggaatac cagctggagt tgaacaacta ctttttaatg caggtaaatt
     2581 gattgttcaa gtatttatag ttactatggg aacatcagca attgcatcca atgcaatagg
     2641 aatgtcaatt gcatccataa taaatgtaat tgggaatgct ttagctttgt ctgctacaac
     2701 cttggtggga cagtatatag gacgtggaga tattaaagga gctaagagta ctttattata
     2761 tttaactaaa tttgcaacaa tttgtttatt tatagtagga gctatattta taccaattgc
     2821 accttggatt tcaagtatgt atactcaaaa tgctagtgta attgacatct caacacaatt
     2881 aattcgaagt gattgtttag ctatggtaat atggcctata tcctttgtat tatcagcagg
     2941 gctaaaggga gccggtgata ctagatatac aatgatgact gcagtaatag gtatgtggat
     3001 ttttagaatt tttacaggtt acgtattggg ggttgtatta gaatttggag tgttaggaat
     3061 ttggataggt atgtatactg attggcttgt tagagggact ttatattgtt taagattaag
     3121 aggaacaaag tggctaaaac acaaagttgc atagaatata tgaaatcact tttagatgga
     3181 taactctatt tagaagtgat tttttatgta gttattatca taattataag tatgatatat
     3241 aaggtgatta aattacataa ataaagccta taatagtatg gatactataa attatatatt
     3301 gagcagaatt acataatttg gcgataaata ttagaaatat atatctatag aaaataatat
     3361 atatgggtat attattaaat ataaaaaata ttaggtattt atttaataat aaaggtgggt
     3421 attgttatga taaataaaat aggaaaaata actctctatg taaataatca agaggatgca
     3481 aagttgtttt ggacagaaaa attgaacttt gtagtaactt atgaaaagga aatgggtcca
     3541 aatatgaaat gggtggaagt agcaccaagt aaaaatgaat ttacaacatt tgtgttgtat
     3601 gataaaaatc taatgatgag acaaaacaaa gagataaatg tatctcatcc atcaataatt
     3661 ttaagtacaa gagatattaa tggaacttat gaacaaatgg caaataacga ggttgaggtt
     3721 ggggaattaa tggagatgcc atatggaagg atgttttctt ttaaagacca agatggaaat
     3781 gattatttgg tcagagagga taaataattt tacaaagtat taaatttact caatatctga
     3841 tataattaga gacaataatt attataaact agtctaggat tagaattata taattaaaaa
     3901 ttaagtgtaa attttgagta gaggtgataa aatgtttaag aaaatggcag tactaaaaga
     3961 tatagcaact aaaataggtc gtaaaaaagc ttatgaacta ttagaaatgg ttgaaggtaa
     4021 tgatgccttt gtagctgagg tgaagataaa aaagaatgga atagaatcta aaaaagaaga
     4081 aattatgtta aaagataatc aaaaaataat attagagtat atagaaggct aatttttaaa
     4141 tacatataag ttgatatact aaatttctga gatgagttta cataaaactc atctttttta
     4201 cttttcaata actttgtttt attatttaat atacatttta tctgcttaga gttgctgata
     4261 tataaaaatt actgatataa taaaagaatg gatattaatg taatatttta tagaaaagag
     4321 gggtattatg cttgaaataa aaaatctttc ctttaatgtt gagtctaaca atgaggaact
     4381 aggaataata aatgatgtta gcctttcatt tgagagggga aaacttattg ttatcacagg
     4441 gccaaatggt ggaggaaaat ctacaattgc taagcttatt atgggaattg aaaaagctac
     4501 gagtggtcag ataattttag atggagaaga tataacaaat cttagtatta cagaaagagc
     4561 aaaaaaagga ataggatatg catttcaaca accaccaaga ataaaaggta tgacagttga
     4621 aaatttactt acacttgctc atggaaaacc attgtctact gatgtatgtt gccaatatct
     4681 tacagatgtt ggattgtgtt caaaagacta tttaaatcgt gaagttgata actctctttc
     4741 tggaggggaa atgaaaagaa ttgagatagc aactcttttt gctagagatt taaaggtttc
     4801 tatatttgat gaacctgaag cagggataga cctttggagc tttgggaaac tcaatgaaag
     4861 ttttaagaaa atacatgaag agtctaacca gactataatc ataatttctc accaagaaag
     4921 aatattagag ttagctgatg aaataattgt tctacaagat ggttcagtaa aaagccatgg
     4981 aacaaaagag gctatattac ctgaaatcat gtgtcaagtt aattcaagtt gtgaattaat
     5041 gaaagacatg aattaattag aaaggaaggc aaattaaatg aacaaaatag atttaaatct
     5101 tttagaaaaa gttgctgaac ttcgtggaac tccattagga gcatacaata tacgtaaaaa
     5161 tgggcaagga gtagagagac attcaactga aaatgtaact ataattccta aaactgataa
     5221 acctggaata gatattatag taaagccaaa tacaaaagga gaaaatgtac atataccagt
     5281 aatagtaaca gagactggtg tacaggatat ggtatataat gattttgaaa ttggagaaaa
     5341 tgcagatgtt gttataattg ctgggtgtgg tatacataac tgtggttgtg atgatagtga
     5401 acataatggt atacatagat ttttcttacg taaaggagct cgcctaaaat atgtagaaaa
     5461 acattatggt gaaggtgatg gagaaggaaa gagaatttta aatccagtta ctattgtcaa
     5521 tatggatgag gattcatatt gtgaaatgga aacaattcaa attaagggtg tagattcaac
     5581 taaaagagaa atggatgcaa acctaggtaa aggagctaaa atagttgtat ttgagaaatt
     5641 attaactcat ggtaatcaag ttgcagaatc taatatgaag gttatcttag agggggaaaa
     5701 ctcttctgct caagtagttt ctcgtacagt tgggcaagat aattctaagc aaaagtttaa
     5761 tccttgtgtt attggggatt ccctttgttc tgcacatgtt caatgtgatt caataattat
     5821 gggaaattct caaattagtg ctatacctga aattgctgca aatcatccag atgctctttt
     5881 agtacatgaa gcagctattg gaaagattgc aggagatcaa atactaaaga tgatgacatt
     5941 aggtcttact gaagaagaag ccgaacaaca gatacttaat tgcttcttaa agtaaattaa
     6001 agattttatt taatttaata taattaatat agtataatat agtgaataag tctaaaatat
     6061 ttttattttt aggcttattt tctttatgta agaaaagcta ttagagaaat tatattgtaa
     6121 ttaggatgtg gaataaatga aaaatttgct tataagaaat gggacaataa tatctccaac
     6181 agatggtatc aaatttgaaa aaagagatat cttggtttta catgggaaaa tatatgctat
     6241 tggattgaac cttaaagaga aaataagaaa agaaaaatta cttacaaata aagagttcga
     6301 gataataaat gccgataata tgtatatttc cccaggattt atagatgttc acacccattg
     6361 ttataagaga aaattaccta caggtatgga ttctgattca attggaattg aaaaaggttc
     6421 tacagttata tttgatgcag gtacagctgg tcctttaaac tactatgatt ttaaaaaaaa
     6481 gtatatggat gagtgtaaaa cagaagtata ttctttttta aatgttacaa atgagggact
     6541 aaatatattg aatgaatcaa cttctttaga tgttataaat tttgacaagg ttgagtcagt
     6601 tgtagaaaaa aatatagaaa agataaaggg tataaaagta aaagcgagta aatttcaatc
     6661 taatgaaagt ggtatagata taattaagaa atcaaagcaa gttgccaaaa aattaaattt
     6721 acccttagtg gtatatatag gagagtatcc atcatatata gatgaagtaa tgaatatttt
     6781 gggaaaagga gatgtggtta caccagtata tggaaatagt acaaatggaa tccttaaaga
     6841 atctggcaca ttaagaaaat cagtaataaa tgcaaagaac agaggagtat tgtttgatgt
     6901 atgtcatgga ttgaaccaat ttgattttaa agtttttaaa aaagcaataa agcaaggttt
     6961 agagccagac ctaataagta ctgatatgca tataaaaaac atgaaagacg taaactattc
     7021 tcttttaagt gttataaata aaattatgga acttgggata tccttagaaa agtgtataga
     7081 aaaagtaact gaatacccaa caaagatttt cgatttacat ggaaataaag gcagaataaa
     7141 gattggtgga gaaggtgatt ttacaatatt cacaatggag gagtgtaatg atattataaa
     7201 agactacaat aataatgaac ttgttttaaa taaaaaatta agattgcaat atactgtaaa
     7261 atcatggatg aaaagcagtg aagtttatag acatggatac gaaaatacta taataaacta
     7321 aacaatagtg ataaaataat aaatatatgt ttaaattggt atatattgga taaatatcta
     7381 aggaaacaac aattaaaaaa taataatttt aggggaggta ttttagtatg aaagcatttg
     7441 ttgataagga tgtatgtgta gcttgtggag catgtatagg aacatgtcca gacgttttta
     7501 gtatgagcga tgaagggcat tcagtagcaa ttgaaggaga aataccagca gacttacaag
     7561 atttatgtaa agaagccgaa gaaggatgtc cagtttcagc tataacagtt aaatagagct
     7621 gtttaaattt atttttaaaa taaatatata agatttaatt gggtacttaa gctatagtat
     7681 tagaaatttc tattactata gctttttaaa atagataaac ttaatatata agatattact
     7741 ttttacaaat atggaggact gaaatatgaa aaaaaattat gaaatagtat tattcgattt
     7801 agatggaaca cttacagacc ctaaagaagg aataacaaag tctattcagt attctttaaa
     7861 tagctttggc ataaaagaag atttggaaaa cttagaccaa tttataggac caccattaca
     7921 tgatactttt aaggagtatt ataaatttga agataaaaaa actaaagaag ctgttgaaaa
     7981 gtatagagaa tattttgctg ataaagggat atttgaaaat aaaatctatg agaatataaa
     8041 agagatatta gaaatgctct ataaaaatgg taaaatatta ttagtagcaa cttctaagcc
     8101 aacagttttt gcagaaacta tacttagata ttttgatata gatagatatt ttaaatatat
     8161 agcaggtagc aatcttgatg gtacaagagt gaataaaaat gaagttatac aatatgtact
     8221 agacctatgt aatgtaaaag ataaagataa agttattatg gttggagata gaaagtatga
     8281 cataattgga gccaaaaaaa taggtataga ttctattgga gtgttgtatg ggtatggttc
     8341 ttttgaagaa cttagtgaaa gtgaacctac ttatattgtc gaaaatgtag agtctataaa
     8401 agatattttg ttataaatat cttttataga caaaaatatt acaaaatggt gtcgcatatt
     8461 taaaaatatg atattatagt taaggaagtc atttaaaaaa gaggaggatg cacttaaaat
     8521 gaaatctatt ttaattatgg gtggaagcga cttcataggt tctgcacttg ctaagcgctt
     8581 gattaaatgt gggtatcaaa ttgatatact tacaaatggt aaaaaggaaa tagattataa
     8641 tggttttaaa gaacatctaa tttgtgatag aaaagttcga aaagatatgg aaaacattat
     8701 cacaggaaga aaatatgatt acatatatga tatgacagca tatacaaaag aagatgtaag
     8761 taatctgatt gattttataa gtatggataa cttaaaaaag tatatagtat tgtcagcagg
     8821 agcagtatat aaagatagtg gaagaaatat aaaagaagaa aatgagaaag gtgaaaatga
     8881 aaactgggga aaatatgggt taaataaaaa agaggctgaa gattttatta taaatagccc
     8941 tataccatat ataattatta gaccaactta tatatatggt gaaaataata atttatatag
     9001 agagtattat ttctttgaaa aaatagaaaa aaatgaaaag ataccagtac caaaaggaaa
     9061 acaagttagt aatcaattta tatatattgg ggatttggta aaggtattgg aaagcataat
     9121 gaaaaatcct catgtaagag aggcctataa tgtgacaaat ccacagttaa tttcttggga
     9181 tgaccttata tatacatgtg gagaaattat tggcaaagaa cctataataa aatatgtaga
     9241 tatggaaaaa gtagagttta gagaaagaac gtatttccca tttagaaata tagactttaa
     9301 tcttgatata aataagctta ttgaacatgg gctttatata ccaaatgtgt tactaaaaga
     9361 aggtcttaca gcaacatata aatggttttc agcaaataag ccaaaaatgc atgacagaaa
     9421 aatgaacaaa gttgagtctg taatgcaaat agtttaaaaa aataaataag taggtagata
     9481 ttttgaactc aaaaattaag tattttttaa aattttttat cttaatattt attttgattt
     9541 ttatatactc agttgcgata gagccgagtc tattaattgt gaaaaaatat aatataagtg
     9601 aaaatggaac attgataaaa agtgatacaa ttgagagtaa atctgaaagg ataaaagtag
     9661 ttcaaatttc agatactcaa ataggtagtt tttattcaac taagaatctc aaaaaagtag
     9721 ctaataagat taacactttg aatccagata taatagtatt tactggtgat ttaattgatt
     9781 actccaataa aaatccaagt gtagatgaaa ttacaactat tttatcaagt atgaatgcta
     9841 ggttgggaaa attttcagta tttggcaatc atgattatat gtataaactt cctaggtatt
     9901 ataggcagat tatgaaaaat tccaacttca atcttttagt aaatgaaaat aaaaaaataa
     9961 aattaaaaga tgataaatat attaatatat taggtgttga tgaaatatta aatggaaatc
    10021 ctaatataaa atatctggag agtcaaatag ataataagaa ttttaattta ttgttagcac
    10081 atgaaccaga tttagtagat atgcttagta aagatacaat gaatttagtt ctatctgggc
    10141 atagtcatgg tggtcaaata agattaccta ttaagggagc attagttact cctccatatg
    10201 gaaggaaata tactaaaggg ttttatgata taaatggaaa tcatttatat gtgagttcgg
    10261 gtcttggaag ta
//
LOCUS       DAEPHU010000108         9990 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 01A10CD0081
            SAMN05941466-rid12468953.denovo.108, whole genome shotgun sequence.
ACCESSION   DAEPHU010000108 DAEPHU010000000
VERSION     DAEPHU010000108.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941466
            Sequence Read Archive: SRR6291087
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 9990)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9990)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068158.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 22:43:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,892
            CDSs (total)                      :: 3,805
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 87
            rRNAs                             :: 8, 1, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 55
            CDSs (without protein)            :: 55
            Pseudo Genes (ambiguous residues) :: 0 of 55
            Pseudo Genes (frameshifted)       :: 21 of 55
            Pseudo Genes (incomplete)         :: 28 of 55
            Pseudo Genes (internal stop)      :: 16 of 55
            Pseudo Genes (multiple problems)  :: 8 of 55
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9990
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941466-rid12468953.denovo.108"
                     /strain="01A10CD0081"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            <1..1417
                     /locus_tag="KR231_003432"
     CDS             <1..1417
                     /locus_tag="KR231_003432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HBH0005764.1"
                     /translation="IKDKYKELFLKIEELDTILNLSKDGILFTSKDGEINTYNSKVKD
                     ILDINEDIYGKYIEDIFVDSLKVLLSEKEILDKVVVFNKKYINVNKKNIYNRDEKMGT
                     YYSLQEITYIKKLEQNLTKKLREKGQIAKYTFKDIKTNSPKMFECIDLAKKVSKSDLS
                     ILIRGESGTGKELIAQSIHNNSNRKNQPFIAVNCAAVPENLLESQLFGYDKGTFTGGL
                     KDGKQGLFELANNGTIFLDEIGDMPLELQTKLLRVLQEKQIMPVGSHNVINIDVRIIS
                     ATNKNLEQMIDNSQFREDLYYRLNTIPINIPPLRERKEDILIIMEDLINKKLVITPEA
                     KKLIQNYMWKGNIRELQNVTSYLNIMCEDIVLEKDLPPNLRSSDNKNTSLKLKYSKND
                     ILNILEILILNKESDVGIGRGLILKALLDKNLQITEGKIKKIFEYLKKEELIICSSGR
                     YGSKITQKGEDFYNKLKYKGL"
     gene            1786..3006
                     /locus_tag="KR231_003433"
     CDS             1786..3006
                     /locus_tag="KR231_003433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HBH0005765.1"
                     /translation="MQQALKLKYQTKELGKDFVIESCNSIKPWLINIRRELHKIPELA
                     LEENLTKQKVISYLKEIGIDYMEFTKHNGIMAYILKESADKTICIRADMDALPIEEEN
                     NIPYKSIHSGKMHACGHDAHTTMLLGACKVLHSIKDKLNVNVKFLFQPAEEGFGGAKF
                     LVEDGCLENPKADYIFGLHVMPHIETGLIETKYDTLNASVDTIKISIKGKRAHGAYPE
                     NGIDAIVTASQIVTSLQTIISRNLEPNNAVVLTIGKIYGGDAHNVICEDVKLEGTLRT
                     LNSKTRNFMIDKIAKIVGDTASAFGCVGTLHVSDENYPAVINEKELVDTVISNTKELL
                     GEEKFILRPNPSLGGEDFSFYTEHCKGAFFHLGCKNEEKGLISPLHTSSFNIDEDCLP
                     IGVMMHVMNTLYFN"
     gene            3043..4392
                     /locus_tag="KR231_003434"
     CDS             3043..4392
                     /locus_tag="KR231_003434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HBH0005766.1"
                     /translation="MEKAKKLGLFSMILLGINSIIGSGIFLLPGKVYNLAGQNSMFIY
                     IFATLLVLSILLCFAEVGSMFDKKGGAYLYSKKAFGDFIGFEVGTMSWVIRIISWSTL
                     AVGFATALGSFWPESATEYKGYIAAILVTLLSINSLFGIKSTKIMNNVITIAKLVPLI
                     VFIIVGIFFIKFVNIVPSGNVVNSSMGPAIILVFYAFTGFESFIVASGEMENPKKNLP
                     VALITTIFICAIIYILIQIVCMGILGDRLFENSIPIADASSVFVGNYGKVFISVATLI
                     SIFGINIGSSIVTPKCGSSLAEEGSLPAFIGKTNKYGAPYVAIIISLICCIPLVLTGS
                     FEQLAVMSVIARFAQYIPTCLSVIVLRKRTDVKASFKIPFGPVIPIVAILGSLWLLQQ
                     AWAEDISKPITQNRVLIGLGAMLLIAPLYIFMKKNKEIEHKNKSEDSKLYISREKIQ"
     gene            complement(4524..4817)
                     /locus_tag="KR231_003435"
     CDS             complement(4524..4817)
                     /locus_tag="KR231_003435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888011.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0005767.1"
                     /translation="MISMIMMLIGVLFIVFGIILTAVEIKGKMPGFYGVGQNAVRKNA
                     IGIIAAGIALIFFRNGLDSIDSILTYGVFLVIELVVIGLYFLIRIKYDKDGNL"
     gene            complement(5303..5506)
                     /locus_tag="KR231_003436"
     CDS             complement(5303..5506)
                     /locus_tag="KR231_003436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0005768.1"
                     /translation="MSFGKRIEMNNIGVETRGVCTIMCPYTCKMMASSSCNCKNNDYN
                     ARGGSYNTYYNKLIHGQRTPDGM"
     gene            complement(5557..5808)
                     /locus_tag="KR231_003437"
     CDS             complement(5557..5808)
                     /locus_tag="KR231_003437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide maturation system acyl carrier-related
                     protein"
                     /protein_id="HBH0005769.1"
                     /translation="MNYTEKELLLENIFFDVTGINFNKNNNLKKELFFSPSLHIQPRE
                     LLLVFCEVIENFNIKIPEEKLLNRQFTSFDNVLKIINMV"
     gene            complement(5824..6894)
                     /locus_tag="KR231_003438"
     CDS             complement(5824..6894)
                     /locus_tag="KR231_003438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR04066 family peptide maturation system
                     protein"
                     /protein_id="HBH0005770.1"
                     /translation="MEKVLIYPFNYNFFTILNHCNKISDIEINSLVSPSGWGLCNKEY
                     NVNNIITKVTNDFQSELKKNSLVWFVDSKENLDLEKFIIPKLKVALKEGKKILYTRDD
                     LNKISRYISHYEFKKINEWNLEKYEIRDIEGISQINTPIIFICGLYGGLDTFDVNIRI
                     GEELRKRGFSILQFGPKKESYLFKMIPIPEFMFDDSISSKTKIINFNHFIKDKEVEAK
                     PDLIIIEVPGELFPFSRKMVGNFGIRAFEISNAVINDCGILCIPSSIYDREYCEELKY
                     FIKGRHGINIDYFSIEKKVIDTYETEVKQKFSYMSLDENFFVEDIEDYEKTFFIHDNK
                     QLLELVDNIVNQLKEYAKVISI"
     gene            complement(6923..8344)
                     /gene="ccpM"
                     /locus_tag="KR231_003439"
     CDS             complement(6923..8344)
                     /gene="ccpM"
                     /locus_tag="KR231_003439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cys-rich peptide radical SAM maturase CcpM"
                     /protein_id="HBH0005771.1"
                     /translation="MNQKPFIHTFKAGKSYFIYDVNTDKILKVNAAVYNYLNKIEHNL
                     EKESDWNIEIEDEINTLINYGFLKNKRVSKTMHPETKYIKYHIENNLSSIILQVTQNC
                     NLRCDYCIYSGSYSNRVHTNKRMNIDVAKRSIDYLIKNSSQLNEVSVGFYGGEPLLEF
                     DLIKQIVEYVKVVGEGKEIYFNLTTNATLFNEEIIEFFVKNNITTMISLDGGKEIHDK
                     SRKFANTGEGSHDVVLKNVRYIKNKYPEYYKKNITFNTVINSENDYISIDDFISKNET
                     LKDSNFLASTLNNNYSDKEIVSSDEYILGKSYDRFLTLLNKLKFIKDESMSPLSRIER
                     ALLDDFRYEKNIEGRLELPDVWHHGGPCIPGAFRIFVTTDGEFFPCERVSESSKMGMI
                     GNLDSGVDIEKAEKLLNIGKLYEEQCSDCWAYSYCDICIAKIDDTKCNENEIKPHDCD
                     RIRHSTENNMKDYCVLKSLGYQY"
     gene            complement(8366..>9990)
                     /locus_tag="KR231_003440"
     CDS             complement(8366..>9990)
                     /locus_tag="KR231_003440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH0005772.1"
                     /translation="IINNMQTFSKSVKEILVLLIMYLIINIIPSIFQSFYGYYRIKFN
                     KNFEKHIETMMLEKSLTLSLKDFEDDNTYDMINRAQSQKGFNITILSENLISIIRESV
                     STLSLIVVLSQFQLWLIIVVIVIPVLKSLYSIKLGKEQYDVSVNRTWKERKAWYIDYL
                     LSKGYAYKEIMVFRIGSKLINHYKKLKEDIISQDMNIAKKNFIATLLCTVLDSIVSAG
                     IIGFIIIQGILKKILIGDATTYIQAVQSIKDNVESIFSLFSSVIQDLFYTDLLFKFLD
                     YNCKEDSIEHIKIFEKIGDINKIELINISYKYNHSSEYSLKNINLTLNKNDPIAILGK
                     NGSGKTTLLKILLGFYDDYEGDILINGKNLKDIEKDEYIRKVSCMFQDYIKYEATLKE
                     NVAMGDVYKSNLEEKVKSKLKETKLKPSIYEEDGLETILGTWFGKKQLSMGEWQKVAI
                     SRTLMKDADMYIFDEPDSSLDSEAGNELLSLYKKTFENKIGIFITHHIQHAKKITNNI
                     VVLENGKLLESGRHDELMDKKGVYFNLFCNCK"
BASE COUNT         3735 a         1402 c         1159 g         3694 t
ORIGIN      
        1 tataaaagat aaatataagg aattattttt aaaaatagaa gaattagata caatcttgaa
       61 tttatcaaaa gatggtatat tatttacttc aaaagatggt gaaataaata catataatag
      121 taaagtaaaa gatattttag acataaatga ggatatatat ggaaaataca ttgaggatat
      181 atttgtagat agtttaaaag ttttattgag tgagaaagag atactagata aagttgtcgt
      241 attcaataag aaatatataa atgtaaataa aaaaaacata tacaatagag atgaaaaaat
      301 gggcacatat tatagtttac aagaaataac atacataaaa aaattagaac aaaatctcac
      361 taaaaaatta agagaaaaag gacaaatagc aaaatataca tttaaggata taaaaacaaa
      421 tagtcctaaa atgtttgaat gtatagattt agctaagaag gtttctaaat ctgatttaag
      481 catacttatc agaggtgaaa gtggaactgg taaagaactc atagctcagt ctatacataa
      541 caactcaaat agaaaaaatc aaccctttat agcagtaaat tgtgcagccg ttcctgaaaa
      601 tttattagaa agccagctat tcggatatga caagggaact tttactggag gtctaaaaga
      661 tggaaaacaa ggattatttg aacttgctaa taatggaaca atattcttag atgaaatagg
      721 cgatatgcct ttagaattac aaacaaaact acttagagtt cttcaagaaa agcagataat
      781 gcctgttgga tctcacaatg taattaatat agatgttaga atcatatctg ctacaaataa
      841 gaatttagaa caaatgattg ataatagcca atttagagag gatttatatt atcgattaaa
      901 tacaattcca ataaatatac ctcctctaag agaaagaaaa gaagacatat taattattat
      961 ggaagattta attaataaga aattagtaat cacaccagaa gcaaaaaaac ttatacaaaa
     1021 ctatatgtgg aaaggtaata taagagaact ccaaaatgtt acatcctatt taaacattat
     1081 gtgtgaagat attgtattag agaaagattt acctccaaac ttaaggtctt cagataacaa
     1141 aaatacatca ttaaaactaa aatatagtaa gaatgatata ttgaatatat tagagatact
     1201 aattttaaat aaggaatcag atgttggtat tggtagagga ttaattttaa aagcactact
     1261 cgataagaac cttcaaatta cagaaggaaa aattaaaaaa atatttgaat atctaaaaaa
     1321 agaagaactt ataatttgta gttcaggaag atatggaagt aaaataactc aaaaaggaga
     1381 agatttttac aataaattaa aatataaagg tctataaaat tataatttat caaacaaaga
     1441 aatctattca ggattaaagt actccttcaa taggtttttt tatttttcaa gtaccctaaa
     1501 attataattt attttgtaca taaataatag gaattaatag gaataggata atttttttat
     1561 ttcctatttt ttttatataa actagcatat aaaatatatt ttcttcaaaa taatattttt
     1621 tactgaaaat tgaaactatg caatcatttt ttatactata catatagata aatgattata
     1681 tttattcaat attcttataa aaaacaaaat tctccatcga aaattatggc ataataattg
     1741 cttattatat taataaaaca ataaaaagca attggaggaa taaaaatgca acaggctttg
     1801 aaattaaaat atcaaaccaa agaattagga aaagattttg taatagaaag ttgtaattct
     1861 ataaaaccat ggcttataaa cataagaaga gaattacata aaattccaga attagctctt
     1921 gaagaaaatc ttactaaaca gaaggtaatt tcttatttaa aagaaatcgg aattgattat
     1981 atggaattta caaaacacaa tggaattatg gcatatattt taaaagaaag tgcagataaa
     2041 acgatttgta taagagcaga tatggatgct cttcctattg aagaagaaaa caacatacct
     2101 tataaatcaa tacattctgg aaaaatgcat gcttgtggcc atgatgcaca tacaaccatg
     2161 ctacttggag catgtaaagt tttacattca ataaaagata aacttaatgt aaatgtaaaa
     2221 ttcttatttc aaccagcaga agaaggtttt ggaggagcaa aatttttagt tgaggatggg
     2281 tgtttagaaa accccaaggc cgattatata ttcggacttc atgttatgcc acatatagaa
     2341 acaggcctta tcgaaacaaa atatgataca ttaaatgcta gtgtagacac tataaaaata
     2401 agtatcaaag gtaaaagagc tcatggtgca tatcctgaaa acggtattga tgcaatagtt
     2461 acagcttcac aaattgttac atcattacaa actataataa gtagaaactt agaaccaaat
     2521 aatgctgttg ttttgactat aggtaaaata tatggtggtg atgcacacaa tgtaatatgt
     2581 gaagatgtaa aattagaagg cactttaaga accttaaata gcaaaacaag aaactttatg
     2641 attgataaaa tagctaaaat tgttggagat actgcatctg catttggttg tgttgggact
     2701 ttacatgtaa gtgatgaaaa ctatcctgct gttataaatg aaaaagaatt agtagataca
     2761 gttatatcaa atactaaaga attacttgga gaggaaaaat ttatattgag accaaacccg
     2821 tctttaggtg gtgaagactt ttctttttac acagaacatt gtaaaggagc attcttccat
     2881 ttaggatgta aaaatgagga aaagggctta atttcacctc ttcatacctc tagctttaat
     2941 atagatgaag attgtttacc aataggtgtt atgatgcatg taatgaatac tttgtatttt
     3001 aattagtaca gtaattaata aaagaatagg agataaatta atatggaaaa agctaagaaa
     3061 ttaggtctat ttagtatgat attattaggg attaatagca taataggttc aggtatattc
     3121 ttactaccag gtaaagttta taatctagca ggtcaaaaca gtatgtttat atacattttt
     3181 gctacactct tagttctatc aatactttta tgttttgcag aagttggaag catgtttgat
     3241 aagaaaggag gagcatatct atactccaaa aaagcttttg gagattttat aggatttgaa
     3301 gttggtacaa tgtcttgggt tattagaatt atatcatggt ctactctagc agtaggattt
     3361 gcaacagctt taggttcatt ttggccagaa tctgccactg aatacaaagg ttatatagct
     3421 gcaatactcg taacactact ttcaataaat agcttatttg gaattaaaag cacaaagata
     3481 atgaataatg taataactat agctaaatta gtaccattaa tagtttttat aatagttgga
     3541 atatttttta taaaatttgt aaatattgtt ccttcaggaa atgtagttaa ctctagtatg
     3601 ggtccagcca ttatattagt attttacgca tttaccggct ttgaatcatt tattgtggca
     3661 agtggagaaa tggaaaatcc taaaaaaaat cttccagtcg cattaataac cacaatattt
     3721 atatgtgcaa taatttatat attaattcaa attgtctgta tgggtatact tggagataga
     3781 ctatttgaaa acagtattcc aattgcagat gcttcaagtg tatttgtagg caattatggt
     3841 aaagttttca tatctgtagc aacattaata tctatatttg gtataaatat aggttcatca
     3901 atagtaactc ctaaatgtgg ttcttctcta gcagaagaag gttctcttcc tgcatttata
     3961 ggaaaaacaa ataaatatgg tgctccatat gtagcaataa taatatcttt aatttgttgt
     4021 ataccacttg tgctaactgg aagttttgaa caacttgcag taatgagcgt aattgcaaga
     4081 tttgctcagt acataccaac ttgtttatca gtaatagttt taagaaaaag aacagatgtt
     4141 aaggcctctt ttaagattcc atttggccct gttataccaa tagtagctat tttaggtagc
     4201 ttatggttgt tacaacaagc ttgggcagaa gatatttcaa aacctataac tcaaaataga
     4261 gttttaatag gattaggggc aatgttgtta atagctcctc tatatatatt tatgaaaaaa
     4321 aataaggaaa tcgagcataa aaataaatca gaagattcta aattatatat ttcgagagaa
     4381 aaaattcaat aatattttat actattactt ctcataaaat ataataaata taaaaaaatt
     4441 gtagataaaa ctattttata aaatttatct acaatttttt tatataaaca tatatcaaaa
     4501 tcaaaatatt attaatttat actttaaaga ttcccatctt tatcatattt tattcttata
     4561 agaaaatata atcctattac tactaactct atcactaaaa atactccata ggtaagaatt
     4621 gaatcaatac tatctaaccc atttctaaaa aaaattaatg ctatacctgc tgctataatc
     4681 cctatagcat tttttcttac tgcattttgc ccaactccat aaaaacctgg catttttcct
     4741 tttatttcga cagcagttaa aattatccca aacactataa ataatactcc aataagcatc
     4801 ataatcatac taatcatcta attacctcct tcacttaagg aaatttcaat ttctaaaatc
     4861 taaaataaat aatatttatt ttttataata atattgtata tccaattaac tattttggaa
     4921 attagtacca ataaataatg tttaaatatt gaaataatat attaattcta atcaatatta
     4981 ttaatatata tatacatttt tacaaatata tttaaaaact ttacttttaa ttcttactat
     5041 ttaaataagt ataatttatt ataataactt ttaattaatt tatactttta aattgtaaaa
     5101 atcaccccta atcactatat ttaccactat aataattgaa gaggtgattt atataacaga
     5161 tactatttat gcagttatta taaaatcaca ctcttaatta taatcaactg catattttta
     5221 taataaaagg aaataaagta agaaagataa atttaatcaa atatgctaaa tcaatttaat
     5281 agtatactta ttactgaaat atttacattc catcaggagt tctttggcca tgtatcaatt
     5341 tattataata tgtattatat gatcctcctc ttgcattata atcattattc ttgcagttac
     5401 aagatgaaga tgccatcatc ttacaagtat aaggacacat aatagtacaa acacctcttg
     5461 tctcaacacc tatattattc atttctattc tttttccaaa actcattcat atcctcccct
     5521 tttctataag atcacttact ttataccttt attaacctat accatattga ttatttttag
     5581 aacattatca aaactcgtaa attgcctatt caaaagtttt tcctctggaa tttttatatt
     5641 aaagttttct attacctcgc aaaatactaa aagtaattct cttggctgta tatgtaaaga
     5701 cggtgaaaaa aataattctt tttttaaatt gttattttta ttaaaattaa ttccagtcac
     5761 atcaaaaaat atattctcta gtagtaattc cttttcagtg taattcataa ttaacctcca
     5821 attctaaata gatattactt tagcatactc ttttaattga ttcactatat tgtccactaa
     5881 ttctagtaat tgtttattat catgtataaa aaatgttttt tcataatctt ctatatcttc
     5941 aacaaaaaag ttttcatcta atgacatata tgaaaatttt tgcttcacct ctgtctcata
     6001 tgtatctata acttttttct ctatactaaa atagtctata tttataccat gtcttccttt
     6061 aataaaatat ttaagttctt cacaatattc tctatcatat atacttgatg gaatacataa
     6121 tataccacaa tcatttatta ctgcattaga aatttcaaaa gctctaattc caaaattacc
     6181 aaccattttt ctagagaaag ggaataattc tcctggaact tctataatta ttaaatctgg
     6241 ctttgcctct acctctttat cttttataaa atggttaaaa ttaataatct ttgtcttact
     6301 acttatcgaa tcatcaaaca taaactctgg tataggaatc attttaaata aatagctctc
     6361 ttttttaggg ccaaattgta atattgaaaa cccccttttt cttagttctt ctcctatcct
     6421 tatatttaca tcaaaagtat ctaaccctcc ataaagacca caaataaata ttattggtgt
     6481 gtttatctgt gatataccct ctatatctct tatttcatat ttttctaaat tccattcatt
     6541 aatctttttg aattcataat gagatatata cctagatatt ttattaagat catcacgtgt
     6601 atataatatc tttttacctt cttttagagc tacttttaat ttaggaatta taaatttttc
     6661 taagtctaga ttttcttttg aatcaacaaa ccataccaaa gaattctttt taagttcact
     6721 ttgaaaatca tttgtaactt tagtaataat attattaaca ttatactcct tattgcataa
     6781 cccccagcca gaaggactaa ccagtgaatt aatttctata tctgaaattt tattgcaatg
     6841 atttaaaata gtaaaaaaat tataattaaa tggatatata agtacttttt ccataatccc
     6901 atctttcctt tcattagaaa atttaatatt gatatcctag agatttcaaa acgcagtaat
     6961 ctttcatatt attttctgta gaatgtctaa ttctgtcaca atcatgtggt tttatttcat
     7021 tttcattaca tttagtatca tcaatcttag ctatacatat atcacaataa ctataggccc
     7081 aacaatcaga acattgctct tcatataatt ttcctatatt taaaagtttt tcagcctttt
     7141 ctatatctac tccactatct aaatttccaa tcatacccat tttagaactt tcacttactc
     7201 tctcacatgg aaaaaattct ccatctgtag ttacaaatat tctaaaagct cctggtatac
     7261 atggtccacc atgatgccac acatctggta actctaatct accttcaata tttttctcat
     7321 atctaaaatc atctaataag gctctttcta ttcttgataa aggtgacata ctctcatctt
     7381 ttataaattt taatttgttg agtaaagtca agaatctatc ataactctta cctaatatat
     7441 attcatctga tgaaactatt tctttatcag aatagttatt attaagagtg gaagctaaaa
     7501 agtttgaatc ttttaaagtc tcatttttag atataaaatc atctatagaa atgtaatcat
     7561 tttctgaatt tatcactgta ttaaatgtaa tattcttttt ataatattct ggatatttat
     7621 tttttatgta acgtacattt tttaatacaa catcatgaga tccttctcct gtatttgcaa
     7681 attttctact tttatcatga atttcttttc ctccatctaa actaatcata gttgttatat
     7741 tattttttac aaagaattct attatttcct cattaaataa agttgcattt gtagttagat
     7801 taaagtatat ttcctttcct tctccaacta cttttacata ttctactatc tgcttaatca
     7861 aatcaaactc aagtaagggt tctcctccat aaaagccaac actaacttca tttaattgac
     7921 tagaattctt aatcaaatag tcaatacttc tttttgctac atctatattc attcttttat
     7981 ttgtatgaac tctgttgctg tatgaaccag aataaatgca atagtcacaa cgtaaattac
     8041 aattttgggt tacttgtaaa ataatagagg atagattatt ttctatatga tattttatat
     8101 acttagtttc agggtgcatt gttttactta cccttttatt ttttagaaat ccataattaa
     8161 tcaaggtatt aatttcgtct tctatttcta tgttccagtc actttctttt tctaaattat
     8221 gctcaatttt atttagataa ttataaacag cagcatttac ctttaaaatc ttatccgtat
     8281 taacatcata aataaaatat gattttccag ctttaaatgt gtgtataaat ggtttttgat
     8341 tcattaatta acctcccttt aatatttatt tgcagttaca aaataaatta aaataaacac
     8401 cctttttgtc cataagttca tcatgtcttc cactttctaa caactttcca ttttcaagaa
     8461 ctacaatatt gttagttatc ttttttgcat gttggatatg gtgcgttata aatattccaa
     8521 tcttattttc aaatgttttt ttatataaag aaaggagttc atttcccgct tcagaatcta
     8581 aagatgaatc tggttcatca aaaatgtaca tatcagcatc tttcataaga gttctagata
     8641 ttgctacttt ttgccattca cccatagaaa gttgcttctt accaaaccag gttcctaaaa
     8701 tagtttctaa tccatcttcc tcataaatac ttggtttcaa tttagtttct ttaagtttac
     8761 ttttaacttt ttcttccaag ttactcttat atacatctcc catggcgaca ttttctttta
     8821 atgtagcctc atatttaata taatcttgaa acatacaact tacttttcta atgtattcat
     8881 ctttttcaat atcctttaaa ttttttccat ttatcaagat gtcaccttca taatcatcat
     8941 aaaaacctaa taatattttt aaaagtgtcg ttttacctga accatttttt cctagtatag
     9001 caatgggatc atttttattt aaagttaaat taatattttt taaagaatac tctgatgaat
     9061 gattgtattt atatgaaata tttattaact ctattttatt tatatcccct attttttcaa
     9121 atatttttat atgttcaatt gagtcttctt tacagttata atctagaaat ttaaacagta
     9181 aatctgtata aaaaagatct tgtattactg aactaaataa cgaaaatatt gattcaacat
     9241 tatcctttat agattgaact gcttgtatat atgtagtcgc atctcctatt aaaatcttct
     9301 ttaaaatacc ttgaattatt ataaatccta taattcctgc agatacaatt gaatctaaaa
     9361 ctgtacataa tagcgtagca ataaaattct ttttagctat attcatatct tgagatataa
     9421 tatcctcttt taatttttta taatgattaa taagtttaga accaattcta aataccataa
     9481 tctctttgta agcataacct tttgacaaca aataatctat gtaccaggcc tttctttctt
     9541 tccaagttct gtttacacta acatcatatt gttcctttcc taatttaatg gaatataatg
     9601 atttcaatac aggaataaca ataacaacta ttattagcca aagttgaaat tgtgataata
     9661 caacaataag agaaagtgta gatactgatt ctcttattat tgaaataagg ttttcagata
     9721 gtatagtaat attaaatcct ttttgagatt gagctctatt tatcatgtca taagtattat
     9781 catcctcaaa atcttttaaa ctcaaagtta aagatttctc taacatcatt gtttcaatat
     9841 gtttttcaaa atttttatta aactttattc tataatatcc ataaaaactt tgaaaaattg
     9901 aaggaattat atttatgatt aaatacataa ttaacaaaac taatatttct tttacacttt
     9961 tcgaaaatgt ttgcatatta ttaatgatat
//
LOCUS       DAEPHU010000109         9981 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 01A10CD0081
            SAMN05941466-rid12468953.denovo.109, whole genome shotgun sequence.
ACCESSION   DAEPHU010000109 DAEPHU010000000
VERSION     DAEPHU010000109.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941466
            Sequence Read Archive: SRR6291087
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 9981)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9981)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068158.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 22:43:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,892
            CDSs (total)                      :: 3,805
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 87
            rRNAs                             :: 8, 1, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 55
            CDSs (without protein)            :: 55
            Pseudo Genes (ambiguous residues) :: 0 of 55
            Pseudo Genes (frameshifted)       :: 21 of 55
            Pseudo Genes (incomplete)         :: 28 of 55
            Pseudo Genes (internal stop)      :: 16 of 55
            Pseudo Genes (multiple problems)  :: 8 of 55
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9981
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941466-rid12468953.denovo.109"
                     /strain="01A10CD0081"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            322..1752
                     /locus_tag="KR231_003441"
     CDS             322..1752
                     /locus_tag="KR231_003441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBH0005773.1"
                     /translation="MSSQESKPKGNLISNFRDDMRDPKKRAIYTYSSSINLAYNFIGY
                     FVSTVTNIFLTDVAKLGVIMAGGMQIIQSFIKIAVAPITGTVFDKQPFKKGKYYPWLR
                     YAPAALALTYGIFFIVPLMKISPALLLPLMTALLLIASCAQQVVFTIIYAIYPVVAKT
                     PRDRVIGSTTTNIFKEVGKFLVGFSYPLLLVLFADVLGGEGMGYLGTYLFFAAGCLLV
                     FWFSSTEIIKSGAEEEVLQKEEKPKIKASEMAKALFTNVPLMMAFCLEFLICIRSIGL
                     GPLAPYYFKYVIEDERGLAVFLSIMPLVSVAFMFFAPVFIKICREQKLASIISFSICA
                     LCHLLVAWTPWGKTTLGVTMLLAIGGGFSNVVSIINLNFFAGSCDYGHWKSGKDLPGL
                     SMSLYPVAIQVGVLLATTIRTVLMNSMGYQADMVVTEAVKSGFINMISYSMAIPLIIA
                     VVIAILYPVSDKKLNQIREELNQRNA"
     gene            1855..2958
                     /locus_tag="KR231_003442"
     CDS             1855..2958
                     /locus_tag="KR231_003442"
                     /EC_number="2.6.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidinol-phosphate transaminase"
                     /protein_id="HBH0005774.1"
                     /translation="MIEKLLRNTVKELHQYVPGEPIEKVKEKYGVKEIIKLASNENPL
                     GPSPKAIEAMIEMLKQGQLYPEPEANELRRKLAEKLDLKPENFIVANGADNVITLIGE
                     AFINRGDEVIYCNPTFPSYRTATIKNEGIPVEVPLTEDYKYDLQGILDKITDKTKLIC
                     VCNPNNPTGTIVDDKELEEFLKKVPENIITILDEAYIEFLTVPNYVDGLKYVRENYNV
                     IVTRTFSKIYGLAGLRVGYGIAKDEIIRTLFTVKEPFSANRVAISGATAALDDEEFIK
                     ETYELNRVGMAYFKEEFTKMGFDVVDSQSNFLYVDMKTDIPKLFEDLKKRGFVIRPSA
                     THARVSIGTMEENKKFVAVLKEILNIKGEPSIG"
     gene            2973..3209
                     /locus_tag="KR231_003443"
     CDS             2973..3209
                     /locus_tag="KR231_003443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S binding protein"
                     /protein_id="HBH0005775.1"
                     /translation="MKRGVDMNLKINAERCKSCEYCVISCKKGALKISSKINKEGYAH
                     VEVDESKCILCGICYQVCPDNVFEIIKEEACQEA"
     gene            3226..4275
                     /gene="vorB"
                     /locus_tag="KR231_003444"
     CDS             3226..4275
                     /gene="vorB"
                     /locus_tag="KR231_003444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-methyl-2-oxobutanoate dehydrogenase subunit
                     VorB"
                     /protein_id="HBH0005776.1"
                     /translation="MKKMWKGNHAIAEAALRGGCEFYAGYPITPQTEVIEFLSHRMSE
                     LGRTFIQSENEMAAIYMVYGAYASGMRSMTSSSGPGISLKQEGISYLCANHYPCVIVN
                     VQRWGPGLGSLDSAQTDYLRDTRGGGNGDYHLIVYAPNSIQETVDLMYNSFDVAEKYR
                     VPVEILTEAALGQMMEPVEFPEFKKREGDLGWTYDGSNRDHAKVADNQKPTFCMEKRM
                     RITENEQQWEDYQVEDAEYVFVAFGIPSRTTMNAVRRLREQGEKVGIIRPITVWPFPY
                     KAFEKVSKDVKGFISVESTDTGQLVEDVALTSKKVCKENVPVYGLFSGNHIPKTLQVM
                     DTYSKIKSGEIKEVF"
     gene            4277..5017
                     /locus_tag="KR231_003445"
     CDS             4277..5017
                     /locus_tag="KR231_003445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-oxoglutarate oxidoreductase"
                     /protein_id="HBH0005777.1"
                     /translation="MATEKLTPSVVSIPNKFCPGCGHGIVNRIIAEVIEEHGYEKNHV
                     LTLGVGCVCNMNFSWNGDKMQTAHGRASSTAIGVKVALPDTLVMTYQGDGDAYVIGLS
                     ETLNTAYRNHNVTVFVINNNNFAMTGGQMSWTTMPGQVTTTSVNGRDIKTTGSPLKVP
                     EMVANFFDVAYVARGSVHSPKEIINLKKYIKNAIEAQLNGEGYSLVEILAPCPTNWGV
                     SLEKSIKWMEEEIVPYYALGEFKQRDGE"
     gene            5020..5559
                     /locus_tag="KR231_003446"
     CDS             5020..5559
                     /locus_tag="KR231_003446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-oxoacid:acceptor oxidoreductase family
                     protein"
                     /protein_id="HBH0005778.1"
                     /translation="MEKELVFAGFGGQGVLTLGLIVAESALELGKQVTWMPAYGPTMR
                     GGKAYSVVKFSDESIGGPDMEEIDVLVAMNKPSLDYINLVKEGGTVVINTSAIDENVT
                     LREDISVVKINCQELAQKVNNPKAANIVVLGALIAKTGLFEKELALKTMCDFFEEKGK
                     GKFNVQNEAAFMEGYNNAI"
     gene            5683..7782
                     /locus_tag="KR231_003447"
     CDS             5683..7782
                     /locus_tag="KR231_003447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetate--CoA ligase family protein"
                     /protein_id="HBH0005779.1"
                     /translation="MSLEKLIRPKSIAIVGVTDKLGFGRSAALSIVKSKETDRVYYVN
                     PKREELFGRKCYKTIQEVPEVVDCVVVCTPRNVVPSVLKDSGELGTKAAVVYASGFAE
                     EGTEEGTDLENQLIEISNTYDMKILGPNCMGLLNCIDKVNLWAGGSKWDLDTKKPGIG
                     IVGQSGFITAEIVSSDYFNISYGFSTGNGNIVTLEDAVDFLVDDDYASVIAIYLEGLK
                     NPQKFIDALKRAAQKRKPVIILKSGRSEKGAISAASHTGNLAGSSKAFESIFEKYGVI
                     SVENLEQFMCLAQAFSVLDGNLPANSNFAAINFSGGENTICADLAEENGVELAEISSE
                     TKEEMKKYLPGFATPKNPLDATTALFHEKDMIVGLLHTFEKDDSVGFTMVGANIRDEE
                     NEMHETLCKAVSEAREQGLKKPVFAVPTLEGNRYLDYRTRLEDNQVPIMSSVGTTFTC
                     FNKMAKFIDYDYSKRTLEFKAVKKRESNNVVALSELDSKIEMKKYGVPVPGQGNAKSI
                     DELDEILKYIKYPVVLKINSSEILHKSDVGGVKIGIENRDEAVDAYNEILTNVKKAKP
                     DANIDGILVQEMVESGIEIIIGITNDDQFGPMLLVGLGGVFVEVFKDTTLYPLPINHD
                     EAIMMLKKLKSFKLLNGYRGSEPCDIDALADMMVKLGKYAYENKDEVKEIDLNPVFVY
                     PKGKGVCAVDALIVKYK"
     gene            complement(8049..8564)
                     /locus_tag="KR231_003448"
     CDS             complement(8049..8564)
                     /locus_tag="KR231_003448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferritin"
                     /protein_id="HBH0005780.1"
                     /translation="MISAKMEKLLNEQINHELYSAYLYLSMSSYLEAEGLKGFSNWFY
                     VQYKEETDHAMFFYKYLHNVGGKVQLDAIPMPDSDFTSAMDILERTLAHEKKVTALIN
                     NLAAVANSESDFRTSQFLLWFISEQAEEETNCEDNIKRVKLAGEGGLFFVDQEFANRT
                     YAAPTNPPVTI"
     gene            complement(8656..9867)
                     /locus_tag="KR231_003449"
     CDS             complement(8656..9867)
                     /locus_tag="KR231_003449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family transcriptional regulator"
                     /protein_id="HBH0005781.1"
                     /translation="MSNKQGSNIKDVKIKNKLIILKLLSTNTPMSRVDLAKSTGLTKM
                     TLSNLVTELINENMIREIESSTLNAHSSGRKPILLDISNISPCICGILIRRNICKVII
                     SDLKGNIVKQLSETYPKCLSNDVLKDIIKRMFTKIMKINKRDIIGIGISSIGPVDDIN
                     GTILNPPDFGNVSNLNIVDFIKEMSDLPIFLINDANSGALAEKMYGLGKNISNYIYLH
                     IMNGIGAGLVLENKLHTGNLGQSGEIGHTSINFSGPLCSCGNNGCLDYYTSVSNLIKR
                     IESLSHIYPNSPLINCKDFSLVKLIDEANNKDSLAMFLLDEFCTYVSYALVNTLTLID
                     CSSIIIGYDFNIPGTFIENTLLKKLTASASFSKYKKISVRHSNFGANAPLIGSIAIVS
                     YNFFNGSINFY"
BASE COUNT         3767 a         1230 c         1833 g         3151 t
ORIGIN      
        1 aataaaatta taaaaaatta aaatcactag aaatatgata aaataattta aaatacgcat
       61 ttcaatgaca tttcaaaaca ataaaataat aaaaaacaaa cctaaattaa gtctaaatag
      121 ctttttagtt aattttagta gtaaaaaata aaacttaaaa agtgtttgac aattatgaat
      181 tttgagaata taattaaatt aaaattatac acatataaaa atatactcct gaatcaagaa
      241 tgagatattt aagattcaaa atatatatta ttatacgtga ataataaaaa agtaagaaaa
      301 ttttataagg gaggggtaga tgtgagtagt caagaaagca aaccaaaagg aaatcttata
      361 tcaaatttta gagatgatat gagagaccct aagaaaagag caatatacac atattcaagt
      421 tctataaact tagcgtacaa ttttataggt tactttgtat caactgttac aaatattttt
      481 ttaactgatg tggcaaaact tggtgtaatt atggcaggtg gtatgcaaat tatacaatct
      541 ttcataaaaa ttgctgtagc tcctataaca ggtacagtat ttgacaaaca accattcaaa
      601 aaaggaaagt attatccatg gcttagatat gcaccagcag cgttagcatt aacatatgga
      661 atatttttca tagttccatt aatgaaaata agtccagcat tacttttacc tttgatgaca
      721 gctttattat taatagcatc ttgtgctcag caagtagttt tcactataat ttatgctatt
      781 taccctgtag ttgctaagac acctagagac cgagttatag gctcaactac tacgaatata
      841 tttaaagaag ttggtaaatt cttagtaggt ttttcatatc cgttattatt agttttattt
      901 gcagatgtat taggtggaga aggaatgggt tatttaggta cctacttatt ctttgcagca
      961 ggatgccttt tagtattttg gttttcttca acagagataa taaaatctgg agcagaagaa
     1021 gaagttcttc aaaaagaaga gaagccaaag attaaagcaa gtgaaatggc aaaagcttta
     1081 ttcactaatg taccacttat gatggcattt tgtttagaat ttcttatatg tataagatct
     1141 ataggattag gacctttggc tccatattat tttaaatatg taatagaaga tgaacgtgga
     1201 ttagcagtat ttttatcaat catgcctttg gtaagtgtag cattcatgtt tttcgcacca
     1261 gtgtttataa aaatctgtag agagcaaaaa ctagcttcaa taatttcttt ttctatatgt
     1321 gcactatgcc acttattggt tgcatggact ccttggggga aaactacttt aggagtaact
     1381 atgttgctgg caattggtgg aggtttttca aatgtagtat caataataaa tcttaatttc
     1441 tttgccggtt cttgtgatta tgggcattgg aaatcaggaa aagacttacc tggcttaagt
     1501 atgtcactat atccagttgc aatacaagta ggagtattac ttgcaactac tataagaaca
     1561 gttttaatga actcaatggg atatcaagct gatatggtag tcacagaagc agttaaatca
     1621 ggttttataa atatgatttc ttattctatg gcaatacctt taataatagc tgttgttata
     1681 gcaatactat atccagtaag tgacaagaaa ttaaaccaaa taagagaaga gttaaatcaa
     1741 agaaatgctt agttaaaaga aagttaagta gatggttaat ttaagctatt aaagtaagta
     1801 gacgcaatag cgtttatata aatgaaaata catatacaga gggggctttt aaaaatgata
     1861 gaaaaattat tgagaaatac cgtaaaagaa ttacatcaat atgttccagg tgaaccaata
     1921 gaaaaagtta aggaaaaata tggtgtaaaa gaaataataa aattagcttc aaatgaaaat
     1981 cctctaggac catcaccaaa agcaatagaa gctatgattg aaatgttaaa acaaggtcaa
     2041 ctttatccag agccagaagc taacgaactt agaagaaaat tagctgaaaa gctagattta
     2101 aaaccagaaa attttattgt tgctaatggt gcagataacg ttatcactct aataggtgag
     2161 gcttttataa atagaggaga tgaagttata tattgtaacc caacatttcc atcatataga
     2221 actgcaacta taaaaaatga agggatacca gtagaagtac ctttaacaga agattataag
     2281 tatgatttac aaggtatatt agataagatt acagataaaa caaaattaat atgtgtatgt
     2341 aaccctaata atccaacagg aacaattgtg gatgataaag agttagaaga atttttaaag
     2401 aaagtccctg aaaatattat aactatattg gatgaagcat atatagaatt tttaacagtt
     2461 cctaattatg tggatggact taagtatgta agggaaaatt ataacgttat agtaacaaga
     2521 actttctcta aaatatatgg tcttgcaggg cttagagtag gatatggtat tgctaaagat
     2581 gagataataa gaactttatt tacagtaaaa gagcctttct ctgcaaatcg tgttgctata
     2641 agtggagcaa cagcagcact tgatgatgaa gagtttataa aagaaacata tgaattaaat
     2701 agagttggaa tggcttactt taaagaagag tttacaaaaa tgggatttga tgttgtagat
     2761 tcacaatcaa atttccttta tgtagatatg aaaacagata tacctaagtt atttgaagac
     2821 ttgaaaaaaa gagggtttgt aataagacca agtgctacac atgcacgtgt aagtattgga
     2881 actatggaag aaaataagaa atttgtagca gttttaaagg aaatattaaa tattaaagga
     2941 gagccaagta ttggataata gatagaaata ttatgaaacg gggtgtagat atgaacttaa
     3001 aaataaacgc agagagatgt aaaagttgtg aatactgcgt tatatcttgt aaaaaaggag
     3061 cattaaaaat atcaagtaag ataaacaaag aaggttatgc tcatgtagaa gttgatgaga
     3121 gtaaatgcat actttgtgga atttgctatc aggtgtgtcc agataatgtt tttgaaataa
     3181 ttaaagaaga agcatgtcaa gaggcttaga aggagttggg ataatatgaa aaagatgtgg
     3241 aaggggaacc acgccattgc agaagcagcc ctaagaggag gttgtgaatt ttatgcagga
     3301 tatccaatta caccacaaac agaggtaatt gaatttttat cacatagaat gtctgaactt
     3361 ggaagaactt ttatacagtc cgaaaatgag atggctgcta tatatatggt atatggagca
     3421 tatgcaagtg gaatgaggtc tatgacgagt tcttcaggac caggaatatc tttaaaacaa
     3481 gaagggattt cttacttatg tgcaaatcat tacccttgtg taatcgtaaa tgtacagaga
     3541 tgggggcctg gtcttggctc attggactca gcacagacag actatctaag agatactaga
     3601 gggggaggaa atggagatta tcatttgata gtttatgcac caaacagtat tcaagagact
     3661 gtagatttga tgtataactc atttgatgta gcggagaagt acagagtgcc tgtcgaaatt
     3721 ttgacagaag cagctttagg tcaaatgatg gaaccagtag aatttccaga gtttaagaag
     3781 agagaaggag atttaggctg gacttatgat ggaagtaata gagaccatgc aaaggttgca
     3841 gataaccaaa agccaacttt ttgtatggag aaacgtatga gaataactga aaatgaacaa
     3901 caatgggaag attatcaagt agaagatgca gaatatgtgt ttgtagcgtt cggtatacca
     3961 tcaagaacaa ctatgaatgc tgttagaaga cttagagaac aaggtgaaaa agttggaata
     4021 ataagaccaa taacagtatg gcctttccca tataaagcat ttgaaaaggt aagtaaagat
     4081 gtaaaaggat ttatctcagt agaatcaaca gacacaggtc aattagtaga agatgttgct
     4141 ttaacctcaa agaaagtatg taaagaaaat gtacctgtgt atggtttatt tagtggaaat
     4201 catataccaa aaacattgca agtaatggac acttatagca aaataaaatc tggcgaaatc
     4261 aaggaggtgt tctaatatgg ctacagaaaa attaacacct agcgttgttt caataccaaa
     4321 caagttttgc ccaggttgtg gtcatggaat agtaaatcgt ataatagcag aggtaataga
     4381 agaacatgga tatgaaaaaa atcatgtatt aacattagga gttggttgtg tctgcaatat
     4441 gaattttagc tggaatggtg ataagatgca aactgcacat ggtagagctt catctacagc
     4501 tataggagtt aaagtagcac ttccagatac attagtaatg acttaccaag gtgatggaga
     4561 tgcttatgtt ataggtcttt ctgaaacttt aaatacagca tatagaaatc ataatgtgac
     4621 tgtatttgta ataaacaata ataattttgc aatgactggt ggacaaatgt catggaccac
     4681 tatgccgggt caagtcacaa caacaagtgt aaatggaaga gatataaaga ctactggtag
     4741 tccactgaaa gttcctgaga tggtggcaaa cttctttgat gtagcatatg tagcaagagg
     4801 ttcagttcat agcccaaagg aaataattaa tctaaaaaaa tatataaaaa atgcaataga
     4861 agctcaatta aatggagagg gatattcctt agttgaaata ttagcacctt gtccaactaa
     4921 ctggggtgta tcactagaga aatctatcaa atggatggaa gaagaaatag tgccatatta
     4981 tgctcttggc gaatttaagc aaagggatgg tgaatagtta tggaaaaaga gctagtattt
     5041 gcagggtttg gtggtcaagg agttttaact cttggtctga ttgtagctga gtcagcactt
     5101 gaattgggga aacaagtaac ttggatgcct gcatatggtc caactatgag aggtggaaaa
     5161 gcctatagtg tagtaaagtt ttctgatgag agtataggtg ggcctgatat ggaagaaata
     5221 gatgttttag tagcaatgaa taaaccatct ttagattata taaatttagt taaagaaggt
     5281 ggaacagtag ttattaatac atctgcaata gatgagaatg taacattaag agaagatata
     5341 agtgtagtta aaataaattg tcaggaatta gctcaaaaag taaacaatcc aaaagcagca
     5401 aatatagtag tacttggagc attaattgct aaaacagggt tatttgaaaa agaattagct
     5461 ttaaaaacta tgtgtgattt ctttgaggaa aaaggaaaag gaaagtttaa tgttcaaaat
     5521 gaagcagcat tcatggaagg ctataataac gccatttgat aaattaccct tatcttaagt
     5581 gatttatctc aagatttaat aatctttagt gccaagagaa acttcatctt gagataaaat
     5641 tcacttaaaa tcacaactat aaacatatag gagcgtgaat ttatgagttt ggaaaaactt
     5701 attagaccaa aaagtattgc tatagtagga gtgactgata aacttggttt tggaagaagt
     5761 gcagcactta gtatagtaaa aagtaaggaa acagatagag tatattatgt taatcccaaa
     5821 agagaagaat tgtttgggag aaaatgttat aagacgatac aagaagttcc agaagtagta
     5881 gactgtgtag tagtatgtac acctagaaat gtagttccat ctgtattaaa agattctgga
     5941 gagttaggaa caaaggcagc agtggtatat gctagtggat ttgcagagga aggtacagag
     6001 gaaggtacag atttagaaaa tcaacttata gaaatatcaa atacatacga tatgaaaata
     6061 ttgggtccaa actgcatggg gttgctaaat tgtatagata aggttaatct atgggcagga
     6121 ggttctaaat gggatttaga tactaaaaaa cctggtatag gaattgtagg tcaaagtgga
     6181 tttataactg ctgaaattgt ttcaagtgat tattttaata tatcttatgg tttttcaaca
     6241 ggaaatggaa atatagttac actagaagat gcagtagatt tccttgtaga tgatgattat
     6301 gcatcagtaa tagcaattta ccttgaaggt ttaaaaaatc ctcaaaaatt tatagatgct
     6361 ttaaaaaggg cagcacaaaa aagaaagcca gtaataatat tgaaatcagg aaggtcagaa
     6421 aaaggtgcta tttctgctgc ttctcataca ggaaatttag ctggttcgag taaagctttt
     6481 gaaagtattt ttgaaaaata tggagtaatt tctgtggaaa atttagaaca gtttatgtgt
     6541 ttagcacaag cttttagtgt tttagatggt aatttacctg caaattctaa ttttgcagca
     6601 ataaacttct caggaggaga aaatactatt tgtgcagatt tagcagaaga aaatggtgta
     6661 gaacttgcag aaatatcttc tgaaactaaa gaagaaatga aaaaatatct tccaggattt
     6721 gcaacaccta aaaatccact agatgctaca acagcattat tccatgaaaa ggatatgata
     6781 gtaggtttat tacatacctt tgaaaaggat gatagtgttg gatttactat ggtaggtgca
     6841 aatataagag atgaagaaaa tgaaatgcat gaaacccttt gtaaagctgt aagtgaagct
     6901 agagaacaag gattgaaaaa acctgtgttt gcagttccta cacttgaagg aaatagatat
     6961 ttagattata ggactagatt agaagataat caagtgccta taatgtcatc agttggaact
     7021 acatttactt gttttaataa aatggctaag tttatagatt atgattattc aaaaagaact
     7081 ttagaattta aagctgttaa gaaaagagag tcaaataatg tagtagcatt atcagaatta
     7141 gatagtaaga ttgagatgaa aaaatatgga gtaccagttc caggacaagg taatgcaaaa
     7201 agtattgatg aattagatga aatcttaaaa tatattaagt atcctgttgt tttaaaaata
     7261 aattcttctg aaatattgca caaatctgat gttggaggag ttaaaatagg aattgagaat
     7321 agagatgagg cagtagatgc atataatgag attttaacta atgtaaaaaa agcaaaacca
     7381 gatgctaata ttgatggtat attagttcaa gaaatggtag aaagtggtat agaaattatt
     7441 attggtataa ctaatgatga ccaatttgga ccaatgttat tagtcggttt aggaggagta
     7501 tttgtagagg tatttaaaga tactacatta tatccattac ctataaatca tgatgaagct
     7561 attatgatgc ttaaaaaact aaaatcattt aagcttttaa atggctatag aggaagtgag
     7621 ccttgtgata ttgatgctct tgcagatatg atggtcaagt taggaaaata tgcttatgaa
     7681 aataaggatg aagtcaagga aatagactta aatccagtgt ttgtatatcc taaaggaaaa
     7741 ggcgtatgtg cagtagatgc cttaatagtt aaatataaat agtttataag ttttggtatt
     7801 caaccataat taaagcaccg actgaaaatc acattttgta agttagatag tgtgattttc
     7861 agtcacccca aatttaattt aaaaatattt taaaatgaaa gtatagtttt aagtttaatt
     7921 gtgaaatagc actgtataaa caataaaata ctacgtataa aacgaataat aaaaggtgtt
     7981 ttaatgataa gaatcaatct tgattttcat taaaacacct tctttattat attaaaaatt
     8041 tttaaacgtt atattgtcac aggtgggttt gttggagctg catatgtacg attagcaaat
     8101 tcttggtcaa caaagaatag accaccctct ccagcaagtt taacacgttt tatattgtct
     8161 tcacaatttg tttcttcttc tgcttgttca gatataaacc aaagtaagaa ttgagaagtt
     8221 ctaaagtctg attcagagtt tgctacagct gctaagttgt ttattaaagc tgtaaccttt
     8281 ttttcatgag ctaacgtacg ctcaagaata tccattgcag aagtaaagtc tgaatctggc
     8341 attgggatag catcaagctg aacctttcct cctacattat gtaagtattt gtaaaaaaac
     8401 atagcgtggt ctgtctcttc tttatattga acataaaacc aattagaaaa tcctttaagt
     8461 ccttctgctt caaggtaaga agacatagaa agataaagat acgcagaata taattcatgg
     8521 ttaatctgct cattaagtaa tttttccatt ttagctgaaa tcatttttat acctccaaat
     8581 tttaaatgct cttataaaat ataataatat taaatggaaa aatattcaat aaaagtgttt
     8641 aaatatttta catatttaat aaaaatttat actaccatta aaaaaattat aacttacaat
     8701 ggctatagag ccaattaatg gtgcatttgc tccaaaattt gaatgcctta cacttatttt
     8761 tttatattta gaaaaacttg ctgaagcagt caattttttt aataatgtat tttctataaa
     8821 tgtaccaggt atattaaagt catagcctat tattatagaa ctacaatcaa tcaatgtaag
     8881 tgtattaact aatgcatatg atacgtatgt acaaaattca tcaagcaaaa acatggcaag
     8941 actatcttta ttatttgcct catctattaa cttgactaaa gaaaaatctt tacagttaat
     9001 taatggggag ttaggataaa tatggctcaa tgattcaatt cttttaatta gattactgac
     9061 acttgtataa taatctaaac atccattatt accacaactg cacaatggtc cactaaaatt
     9121 aattgatgta tgtcctattt ctccactttg tcctaggttg ccagtatgaa gtttattttc
     9181 tagaactaga ccagctccaa taccattcat tatgtgtagg tatatataat ttgatatatt
     9241 tttacctaaa ccatacattt tttctgctaa tgcacccgaa ttagcatcat ttatcaaaaa
     9301 tattggcaaa tcagacattt cttttataaa atctactata tttaggtttg atacatttcc
     9361 aaaatctggg ggatttagta tggtaccatt tatatcatct actggaccta ttgaagaaat
     9421 accaattcca attatatctc tcttgttgat tttcattatt ttagtaaaca ttctttttat
     9481 tatatctttt aaaacatcat ttgatagaca tttggggtaa gtttcagaaa gttgttttac
     9541 aatattacct tttaaatctg aaataattac cttacatata tttcttctta ttaggattcc
     9601 acaaatacaa ggcgatatat tagaaatatc taataaaata ggtttacgac ctgatgaatg
     9661 tgcatttaaa gttgatgact ctatttccct aatcatattt tcattaataa gttcagtaac
     9721 tagatttgat aaagtcattt tagtaagtcc tgtagactta gctaaatcaa ctctggacat
     9781 aggtgtattt gtagaaagta atttcaatat tattaactta tttttaattt ttacatcttt
     9841 gatgttagaa ccttgtttgt tactcatcat aaatctcctt aaataaagtt aagtgtttta
     9901 tttattttca agtatactat caccttataa tagagtaaca tttttttact tgaaaatatc
     9961 attaattaga atatatcaca t
//
LOCUS       DAEPHU010000110         9584 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 01A10CD0081
            SAMN05941466-rid12468953.denovo.110, whole genome shotgun sequence.
ACCESSION   DAEPHU010000110 DAEPHU010000000
VERSION     DAEPHU010000110.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941466
            Sequence Read Archive: SRR6291087
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 9584)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9584)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068158.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 22:43:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,892
            CDSs (total)                      :: 3,805
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 87
            rRNAs                             :: 8, 1, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 55
            CDSs (without protein)            :: 55
            Pseudo Genes (ambiguous residues) :: 0 of 55
            Pseudo Genes (frameshifted)       :: 21 of 55
            Pseudo Genes (incomplete)         :: 28 of 55
            Pseudo Genes (internal stop)      :: 16 of 55
            Pseudo Genes (multiple problems)  :: 8 of 55
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9584
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941466-rid12468953.denovo.110"
                     /strain="01A10CD0081"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            491..1696
                     /locus_tag="KR231_003450"
     CDS             491..1696
                     /locus_tag="KR231_003450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase"
                     /protein_id="HBH0005782.1"
                     /translation="MSKKVLIMSASTGGGHNRAALAIKEELTSKTLDGEPIECEIIDS
                     LKLVNNTMDKIISRGYEKSAIYTPKAYGSVYRLSETNLLSKNEFKDNLLITFMAKKFK
                     KLIRSEKPDLIIGTHPFPMIALSTLKKNFNLHNNESNAYTEHFYKHYTNTINVPPLIS
                     VLTDYTTHSTWIQNEIDYYIVGHEYVKELLVFDGVEPSKIRTFGIPVEKSFLSHRDKD
                     IVLSELNLSPDKLTVLLMGGSFGAGNIKETLDELLDTDRDFQILVITGKNESLKEKIE
                     KKLMSRYHDKNVCVLGYTDKMNDILASIDVLVSKPGGLTTTEALLKDVPMIVPYYIPG
                     QEEENLDFLSNCGAALRTTKKYNLSILLKVLIDDPSRLEMLKRNIKSIRKSNSAQNIA
                     NLILNIISG"
     gene            complement(1767..1988)
                     /locus_tag="KR231_003451"
     CDS             complement(1767..1988)
                     /locus_tag="KR231_003451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0005783.1"
                     /translation="MKPIMNLEEHNAMKEKRVKKMKSKDKPKYDDFEDISFSNKKKTK
                     KNVRNKNAEFRNNYKNYQYDYEEDFYEPI"
     gene            complement(2129..2728)
                     /gene="recR"
                     /locus_tag="KR231_003452"
     CDS             complement(2129..2728)
                     /gene="recR"
                     /locus_tag="KR231_003452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012634696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination protein RecR"
                     /protein_id="HBH0005784.1"
                     /translation="MQVYTGPITRLIEEFSKLPGVGRKTAQRLAFHIINMNTNDVEAL
                     SKAIIDAKREIRYCSICCNITDTDPCSMCSNKSRDSSVICVVEDPRDVAAMERTREFK
                     GQYHVLNGVISPMDGIGPDMLKIKELIQRLGNQEVKEIIMATNPTIEGEATAMYIARL
                     VKPMGIKVTRIAHGLPVGGDLEYADEVTISKALEGRREI"
     gene            complement(2741..3091)
                     /locus_tag="KR231_003453"
     CDS             complement(2741..3091)
                     /locus_tag="KR231_003453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009887752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbaB/EbfC family nucleoid-associated protein"
                     /protein_id="HBH0005785.1"
                     /translation="MAKKGFGGGMMPGGGNMNNLLKQAQKMQENMQKAQQELESKEVE
                     ASVGGGAVTVKVNGKKEVIDITIKPEVVDPDDIEMLQDLVLSAVNQALRNIDDIQASQ
                     MSKVTGGMNIPGLF"
     gene            complement(3150..4787)
                     /gene="dnaX"
                     /locus_tag="KR231_003454"
     CDS             complement(3150..4787)
                     /gene="dnaX"
                     /locus_tag="KR231_003454"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit gamma/tau"
                     /protein_id="HBH0005786.1"
                     /translation="MHKALYRAYRPQKFEDVIGQDHIIKTLKNQIYSDNIGHAYLFCG
                     TRGTGKTSTAKIFSRAVNCLNKINEEPCNECEICESVLKDNTMDVVEIDAASNNSVDD
                     IRELRESVKYSPANAKYKVYIIDEVHMLSQGAFNALLKTLEEPPSYVIFILATTEPHK
                     IPATILSRCQRYDFKRVTVKDMTLRMKKICEDEGIDIDDKALNLIARNSQGALRDALS
                     ILDQCMSFGESKIDYKDVVELMGSVNIEQLFELSQCIVEQDTKKSLEILNEFVLWGKD
                     IRNLINDLIDHFRNLMVCKVSSELDEIISLPEETIEQLKIQSKNIDINDLIRILNILS
                     ITQDDIKSSSNPRVLVEITIMKIAQPMFDESKEALIKRVENLEKMIELGNFKSEKIGN
                     NKEKEYEVDREIDVKQENVVYEDVKNEDVILIESSWKNILKQIKKDKKMPIYALLSEV
                     KSFNVYSNMLYVIFDDKFDFAKTRLSSQDTINYLEKTIRDVLNRSFNVKIVLTSEVKD
                     INLEVKEKKDIGEEILKNIVSEEILEIKDSIDENESK"
     gene            complement(4864..5128)
                     /gene="ffs"
                     /locus_tag="KR231_003455"
     ncRNA           complement(4864..5128)
                     /ncRNA_class="SRP_RNA"
                     /gene="ffs"
                     /locus_tag="KR231_003455"
                     /product="signal recognition particle sRNA large type"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01854"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF01854"
     gene            complement(5166..5257)
                     /locus_tag="KR231_003456"
     tRNA            complement(5166..5257)
                     /locus_tag="KR231_003456"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(5221..5223),aa:Ser,seq:gga)
     gene            complement(5258..5713)
                     /locus_tag="KR231_003457"
     CDS             complement(5258..5713)
                     /locus_tag="KR231_003457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside deaminase"
                     /protein_id="HBH0005787.1"
                     /translation="MESSFYMKEALKEAYKAYNKKETPIGAIIVKDNQIIARAHNLTE
                     TLKDSTAHAEILAIKQASEKLGGWRLTDCDLYVTMEPCIMCSGAIVNSRIKKLIIGTR
                     HVKNSYIEKQHEFKLDYFNNNNVKVAFDVLQEECSIILQEFFKALRKRD"
     gene            complement(6034..7305)
                     /gene="serS"
                     /locus_tag="KR231_003458"
     CDS             complement(6034..7305)
                     /gene="serS"
                     /locus_tag="KR231_003458"
                     /EC_number="6.1.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000884181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine--tRNA ligase"
                     /protein_id="HBH0005788.1"
                     /translation="MLDIKRIRENLDDIKKAMERRGEREFDLDAVVELDNKRREILQE
                     VEVMKNELNVNSKKIPQLIKEGKDVTEEKARLKELSDKIKGIDEKVKEVEAKMEYTLM
                     RIPNVPHPEVPQGETDEDNVQIRTWGEPTKFDFEHKAHWDIGTGLGILDFERAGKITG
                     SRFTLYRGLGARLERSLMNFFLNTHTAKHGYTEVLPPFMANRNSFIGTGQLPKFEEDM
                     FKIEGLEYFLIPTAEVPVTNIHANEILDVAELPIKYCAYTPCFRSEAGSAGRDTRGLV
                     RQHQFNKVELVKFVKPEDSYNELESLTHDAETMLQMLGLPYRVVKICTGDLGFTAAFK
                     YDLEVWMPSYNRYVEISSCSNFEDFQARRAGIRFKRDKKSKAEYVHTLNGSGLAIGRC
                     LAAILENYQQADGSVVVPEELRPYMGVDVIK"
     misc_binding    complement(7431..7636)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(7764..8645)
                     /locus_tag="KR231_003459"
     CDS             complement(7764..8645)
                     /locus_tag="KR231_003459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mechanosensitive ion channel"
                     /protein_id="HBH0005789.1"
                     /translation="MNFLSLAKTASTNSNITKRTLENMLDNFSDNIPNIIYAIIVFVI
                     GIYISKIVRRMVSKFLIKYGMSKGVNNFIVYGIYISMLSIISLISLGIIGIQTTSVVA
                     VLGAAGFSIGLAFKEILSNLGSGMIILFFKPFNIGDYIQGSGVEGTVSDIQIFSTVLK
                     TPDNKTIIIPNFQLTSNNIINYTHQNKRRIDFSYNISYDSDIDVVKSILNEIFTNEKR
                     ILNDPKPIIGLNSIGNNTMQIVARPWVKTDDYWDVYFDVMEKVKNKFDENDIKVPFVP
                     SSLLFNNTGNLNTMDKR"
     gene            complement(8657..9166)
                     /locus_tag="KR231_003460"
     CDS             complement(8657..9166)
                     /locus_tag="KR231_003460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription repressor NadR"
                     /protein_id="HBH0005790.1"
                     /translation="MNSNERRSKLIDILKESKHPVKGGTLAELLNVSRQVIVQDIALI
                     RARGFEIIATPQGYIIYNQPYFTKQIKCKNHKDSKEIYDELKIIVDLGGIIKDVIVNH
                     PTYGQITAELNIYSKMDIDNFMKKVETNEFKQLSVLTECSHIHTIEAIKEETIEAIVK
                     ELKDNGILS"
     gene            complement(9292..9408)
                     /gene="rrf"
                     /locus_tag="KR231_003461"
     rRNA            complement(9292..9408)
                     /gene="rrf"
                     /locus_tag="KR231_003461"
                     /product="5S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00001"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00001"
BASE COUNT         3057 a         1678 c         1030 g         3819 t
ORIGIN      
        1 ctcagatact attgttatca aaatatctgg ctttatggtt tgtttcttaa tataaattaa
       61 cctactgttt aattttcaat gttcgtgttt atttcttttt ccttttttca aggacaagta
      121 atactatatc atctttatct attctagtca atataatttt ttactttttt taattttttt
      181 atttatcatg tattctttat ctttaatttt taaaacttaa tgctaagtaa acctgtttat
      241 ttcataaaac taatatatat tctatgctct attttccttt ttattctata tttaaatttt
      301 ttatttacaa gaatattttt aatataacat atttgataaa attaatttac atttctttca
      361 cttgtaattt ttgcaatctt gtattagatt aatattaaaa ataatttatc aataacctta
      421 ttcacaaaga cagtttttat atatcaaaat ataatataaa tactatgcta cattttagga
      481 ggattttatt atgagcaaaa aagtattaat aatgtctgct tccactggtg gtgggcataa
      541 tagggctgct ctagctatta aagaagaact tacttccaaa acacttgatg gagagccaat
      601 tgaatgtgaa ataatagata gtttgaaatt agttaataat acaatggata aaataatttc
      661 aagaggatac gaaaaatctg ctatatatac tcccaaagcc tatggaagtg tatatagatt
      721 atctgaaaca aatcttttgt caaaaaatga atttaaagat aatctactaa taacattcat
      781 ggctaaaaaa tttaaaaagc ttattagaag cgaaaaacca gacttgatta taggaacgca
      841 tccttttcca atgattgctc taagtacatt gaaaaaaaac tttaatttac ataataatga
      901 atcaaatgct tacacagagc atttttataa acattataca aataccatta atgttcctcc
      961 gcttatttct gtattaaccg attatactac tcattctaca tggatacaaa atgaaattga
     1021 ttactatatt gttggtcatg aatatgtaaa agaattattg gtgtttgatg gagttgaacc
     1081 gagtaaaatt agaacatttg gaatccctgt tgaaaaatct tttctctctc acagagataa
     1141 agatattgtt ctttctgagt tgaatttatc tcctgataaa ttaactgttt tacttatggg
     1201 gggtagcttt ggggctggaa atataaaaga gacacttgat gaattactgg atactgatag
     1261 agactttcaa atacttgtaa ttactggtaa gaatgaaagc ctaaaagaaa aaatcgaaaa
     1321 aaaacttatg tctcgttatc atgataaaaa tgtatgtgtc cttggataca ctgataagat
     1381 gaatgatatt ttagcttcta tagatgtatt agtaagcaaa cctggtggac ttactacaac
     1441 tgaggctctt ttaaaagatg tacctatgat agttccttat tatataccag gtcaggaaga
     1501 agagaatctt gatttcttat ctaattgtgg tgcagcactt agaactacaa aaaaatataa
     1561 cttgtcaata ttactaaaag ttttaataga tgaccctagc agattagaaa tgctaaaaag
     1621 aaatattaaa tcaataagaa agtcaaattc agcccaaaat atagctaatt taattttaaa
     1681 tataatttct ggttgataaa ataaataaaa tccctatagt atatatatta tctattaggg
     1741 attttttatt ttctaattat ttaatattaa attggctcat aaaagtcttc ttcataatca
     1801 tactgataat ttttataatt atttctaaat tcagcatttt tatttcgtac atttttttta
     1861 gtttttttct tattagaaaa acttatatcc tcaaaatcat catatttagg tttatctttt
     1921 gatttcattt ttttaactct tttttctttc attgcattat gttcttctaa gttcataatt
     1981 ggtttcatgt tgcaccccta tcaaaatttt taaatgattt atacaacaaa ttatacaata
     2041 cagaagaaat ttattcaata aatctaaatc aaaattaatt tgaatttaac tcaaaaaact
     2101 acaaaaatcg aggtattaac ctcgattttt atatttctct tctgccttct agtgcttttg
     2161 atattgtgac ctcatctgca tactctaaat cgcctccaac aggaagacca tgagctatcc
     2221 gagtgacttt gattcccatt ggttttacta acctagcaat atacatggct gtagcttcac
     2281 cttcaatagt aggatttgtt gccattatta tttctttgac ttcctgattg ccaagtcttt
     2341 ggataagttc ctttattttt aacatatctg gtccaattcc atccattgga gaaattactc
     2401 catttaatac atgatactgt cctttaaact ctctcgttct ctccatagct gctacatctc
     2461 ttggatcttc cacaacacat ataacacttg aatctctact tttatttgaa cacatgctac
     2521 atgggtctgt atctgttata ttacaacaaa ttgagcaata tcttatttct ctttttgcat
     2581 ctataatcgc tttagataaa gcttccacat cattagtatt catattaata atatgaaaag
     2641 ccaatctttg agcagtcttt cttcctactc caggaagctt tgaaaattcc tctataagtc
     2701 tcgttatggg acctgtataa acttgcataa ataccaccta ctagaataac ccaggtatat
     2761 tcatacctcc agttacctta ctcatttgac ttgcttgtat atcatcaata tttctcaatg
     2821 cttgatttac tgcacttaaa actaaatctt gtagcatttc tatatcatct ggatcaacta
     2881 cttctggctt gatagttata tctataactt cttttttacc attaactttt acagtaactg
     2941 ctcctccacc aactgaagct tctacttctt tactttctaa ctcttgttga gctttttgca
     3001 tattttcttg cattttttga gcctgcttta acaagttgtt catatttcca ccaccaggca
     3061 tcattccgcc tccaaaacct tttttagcca taaacactat tcctcctaaa cttattttca
     3121 ttttattatt atatcataat agtattttat tatttactct cattttcatc aatactatct
     3181 tttatttcta atatctcttc actcactatg ttctttaata tttcctcacc aatgtccttt
     3241 ttctctttaa cttcaagatt tatatcttta acttctgatg tcagtactat ttttacatta
     3301 aaacttctat ttaaaacatc tcttattgtt ttttctaaat aatttattgt atcttgagag
     3361 ctcagtctag tttttgcaaa atcaaattta tcatcaaata taacatacaa catattagaa
     3421 tatacattaa aactttttac ttcacttaag agtgcgtata ttggcatttt tttatctttt
     3481 ttaatttgtt taagtatatt cttccaagat gactctataa gtataacatc ctcatttttt
     3541 acatcttcat aaactacatt ttcttgtttt acatctattt ctctatcgac ctcatactct
     3601 ttttctttat tattcccaat tttttcagac ttaaagttcc ccagttcaat cattttttct
     3661 aagttctcaa ctctttttat aagagcttct ttactttcat caaacattgg ttgagcaatt
     3721 ttcattatgg ttatttccac taaaaccctt ggatttgaag atgactttat atcatcctga
     3781 gttattgata atatatttaa aatccttatt aaatcattta tatctatatt tttagactga
     3841 attttaagtt gttctatagt ttcttctggt aatgaaatta tttcatccaa ttctgatgaa
     3901 accttacata ccattaaatt tctaaaatga tcaattaagt catttataag atttcttata
     3961 tctttgcccc ataagacaaa ttcatttaat atctcaagag actttttagt gtcctgctct
     4021 acaatacatt gagacaattc aaataattgt tctatattta cgcttcccat taattcaaca
     4081 acatctttat aatctatctt actttctcca aaagacatac attggtctaa tatactaagt
     4141 gcatctctaa gagctccttg agaatttcta gctattaaat taagagcttt atcatctata
     4201 tcaattcctt catcttcaca aatctttttc attctaaggg tcatatcttt aactgtaact
     4261 cttttaaaat cgtatctttg gcatcttgat aaaatggttg caggtatttt gtgaggctct
     4321 gtagttgcta atataaaaat tacatatgat ggaggttcct ctaaggtctt taataatgca
     4381 ttaaaagctc cttgagacaa catatgaact tcatctatta tatatacttt atatttagca
     4441 ttggctggag aatatttcac actttctcta agctctctta tatcatctac actattattt
     4501 gaagctgcat ctatttctac aacatccatt gtattatctt ttaatacaga ttcgcatatc
     4561 tcacactcat tacacggttc ttcatttatt ttattcaaac agtttactgc tcttgaaaaa
     4621 atctttgcag tagatgtttt accagtacct cttgttccac aaaacaaata agcatgtcct
     4681 atattatcac tatatatttg attctttaaa gtcttaataa tatgatcttg accaataaca
     4741 tcttcaaatt tttgtggtct atatgctcta tataatgctt tatgcatctt tttacctctc
     4801 tttagcaaaa ttaataaaaa aatccctcat tatctaaggg attagtcttt tatatattaa
     4861 atgctgtaca ccatctatcg acttaattcc ataggcgtta ccaaaacagt tagctcaact
     4921 taggcacccc cacggcacac aaaagtgatc acttaccgct gcttccttcc ggatctgacg
     4981 gggttcatga gctttcattg cgcaggacct aagcatcaac accacttatt tagggcggcc
     5041 ctacagaaaa taagccttta gatggaattc aatcctgcta tagcggattg caggttacag
     5101 ggcaccgcta cctccccatc tagtacagca aaattacaac catatttaat tactttcatt
     5161 gtttctggcg gagagagtgg gatttgaacc cacgatacag ttttacccat atactcgctt
     5221 tccaggcgag cgccttcgac cactcgacca tctctcctta atctcttttt ctcaatgcct
     5281 taaaaaattc ttgcaatatg atcgagcatt cttcttgcaa aacatcaaaa gctactttta
     5341 cattattatt attaaaataa tctaatttaa actcatgctg tttttctata tatgaatttt
     5401 ttacatgtct tgtccctatt ataagctttt ttattctaga attaactatt gcgccactac
     5461 acattatgca aggttccatt gtaacatata aatcacaatc agtcaacctc caaccaccta
     5521 atttttctga tgcttgtttt atcgctaaaa tttctgcatg tgccgtagag tcttttaacg
     5581 tttctgtaag gttatgagct ctagctatta tttgattatc tttaactata atagcaccta
     5641 ttggtgtttc ttttttatta tatgctttat atgcttcttt taatgcttct ttcatataaa
     5701 atgaactttc cataattcct cccaaaactt ataacaaact tatcttatca taattcattt
     5761 tataattcaa cttaatttta ttttgtttat ttaattatta ctatatatag ctatattttt
     5821 tttaaattag ttctaaaata atttttagat attcatacaa gagtgtttta taaaaatatt
     5881 tagtgtttta tgatgaaaat tctgctgtgt aaattaacat aaaaaaacta tgaaattaat
     5941 atttataata atttcatagt ttttttattt attgtttact cataatatat tctcttcatc
     6001 aaagcatact ctacatatac aattaatata aatttatttt ataacatcaa cacccatata
     6061 aggtcttaat tcttctggaa ctactacaga accatctgcc tgctgataat tttctaatat
     6121 agcagccaaa catcttccta tcgctaatcc agaaccattt aatgtatgaa catattctgc
     6181 ttttgatttt ttatcccttt taaatcttat tcctgctctt cttgcttgga aatcttcaaa
     6241 atttgaacaa gaagatattt ctacatatct attgtagctt ggcatccaaa cttctaaatc
     6301 atatttaaat gcagctgtaa atcccaaatc tcctgtacat atttttacaa ctctatatgg
     6361 aagacctaac atttgtaaca tagtttcagc atcatgagtt aatgattcta attcattata
     6421 agaatcttct ggtttaacaa atttaactaa ttcaacttta ttaaattgat gttgtctaac
     6481 taaacctctt gtatctcttc ctgctgaacc tgcttcagat ctaaaacaag gagtatatgc
     6541 acagtattta attggaagct ctgcaacatc taatatttca ttagcatgta tattagtaac
     6601 aggaacttca gctgttggta ttaagaaata ctctaatcct tctattttaa acatatcttc
     6661 ttcaaattta ggaagttgac cagtccctat aaaactattt ctattggcca taaatggagg
     6721 taagacttcc gtatagccat gcttagctgt atgagtattt aaaaagaaat tcattaaaga
     6781 tctttctaat ctagctccta atcccctata taaagtaaac cttgacccag ttattttccc
     6841 tgctctttca aaatctaaaa tacctagacc tgtacctata tcccaatgcg ctttatgctc
     6901 aaaatcaaat ttagtaggtt ctccccaagt tcttatttga acattgtctt catctgtttc
     6961 accttgtggt acctctggat gaggaacatt tggtattctc attaatgtat attccatttt
     7021 tgcttctact tcttttactt tctcatcaat accttttatc ttatctgata actctttcaa
     7081 tcttgccttt tcttctgtta catcttttcc ttcttttatt aattgaggta tttttttaga
     7141 atttacattt aactcatttt tcataacttc aacttcttga agtatttctc ttcttttatt
     7201 atctaattcc actacagcat caaggtcaaa ttctctttca cctcttcttt ccatagcttt
     7261 tttgatatca tctagatttt ctcttattct tttaatatct aacatattaa ttcctcctaa
     7321 taattttgat aatataagtt ataattccaa cttaatttac aaacattata cttgtaaact
     7381 cttagtttaa acaaatttta aaaataaaaa aagacctccg tttaccctat aaaagggacg
     7441 aaaatctttt atccgcgttg ccaccctaat tgactatact aaaatgtata atcctctcag
     7501 acctataacg taggtaaacg tctagcttta actagaagct ctagagtaga ttcaaaaacc
     7561 attgtaatga gttttcacca tccactcatt ctctgaatac aatctgtttt ttactatttt
     7621 ccttcacagc tttttaacta attgttttat ttgataatca ttatattata tatattaaca
     7681 tctttcaata ctattattca aattttttta gaattttctt taatttttta tattaaattc
     7741 attttttcta tttaattaag accttatctt ttatccattg tatttagatt acctgtatta
     7801 ttaaataata atgaagaagg aacaaatgga acttttatat cattctcatc aaatttattt
     7861 tttacctttt ccattacatc aaagtataca tcccagtaat catcagtttt tacccaaggt
     7921 ctagcaacta tttgcatggt gttatttcct atagagttta gacctattat aggctttgga
     7981 tcatttaata ttcttttttc gtttgtaaaa atttcattta atatagactt aactacatct
     8041 atatcactat catatgaaat attatatgaa aaatctattc ttcttttgtt ttgatgtgtg
     8101 taattaatta tattattact tgtcagttga aaattaggta taattatagt tttattatct
     8161 ggcgtcttaa gaacagtgct aaatatttgt atgtcagaaa ctgtaccttc tacacctgaa
     8221 ccttgaatat aatcacctat attaaatggc ttaaaaaata aaataatcat accagagcct
     8281 aaatttgata atatttcttt aaaagctaaa cctatactaa atccagcagc tcctaacaca
     8341 gctacaactg atgtagtttg tatccctata atacctaagc ttatcaatga tataatagat
     8401 aacatagata tatatattcc atatacaata aaattattta cacctttact cattccatat
     8461 ttgattagaa actttgaaac catccttctt actattttag atatataaat acctatcaca
     8521 aatacaatta ttgcatatat aatatttggt atattatcac taaaattatc gagcatattt
     8581 tctaaagttc tcttagttat attgctattt gttgaggcag tcttagccaa tgataaaaaa
     8641 ttcattcaac tcctccttat gataatattc cgttgtcctt taactctttt actatagctt
     8701 ctatagtttc ttcttttatt gcctcaattg tatgaatatg gctacattct gtcagaaccg
     8761 ataattgttt aaattcattt gtctcaactt tcttcataaa gttgtctata tccattttag
     8821 aataaatatt aagttctgca gttatctgac catatgttgg atgatttaca ataacatctt
     8881 ttataatacc acctaaatct acaattatct ttaattcatc ataaatttct ttagaatcct
     8941 tatgattttt acactttatt tgttttgtaa aatacggttg attatatatt atatatcctt
     9001 gaggtgtagc tattatttca aatcctctag ctcttataag ggctatatct tgaactatta
     9061 cttgcctact tacatttaat agttcagcta gtgttccacc ttttacagga tgcttagatt
     9121 cttttaaaat atctattaat ttacttcttc tttcattaga attcatatta caccttcttt
     9181 ccaaataaaa actttaccta tactatataa ttttatattt tatcttatta taaatcaata
     9241 ttgactttat attctattta atcttaactt ttataataaa taaaaaagac tacgtggcta
     9301 cgtcctactc tcccaggcag tttcccacca agtaccatca gcgctagaga gcttaacttc
     9361 tgtgttcgga atgggaacag gtgtatcctc tctgctattg taaccacata atctttatgc
     9421 ttaatatttc tattaagttt ttaataagtt tctagaatct agtaatacta gtttctttag
     9481 agttagcact ctaaaaacta cacatatatc ttaatgaatg aacatcaaat aaatattggt
     9541 caagtcctcg acctattagt atcgataagc taaatacatt gctg
//
LOCUS       DAEPHU010000111         9425 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 01A10CD0081
            SAMN05941466-rid12468953.denovo.111, whole genome shotgun sequence.
ACCESSION   DAEPHU010000111 DAEPHU010000000
VERSION     DAEPHU010000111.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941466
            Sequence Read Archive: SRR6291087
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 9425)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9425)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068158.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 22:43:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,892
            CDSs (total)                      :: 3,805
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 87
            rRNAs                             :: 8, 1, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 55
            CDSs (without protein)            :: 55
            Pseudo Genes (ambiguous residues) :: 0 of 55
            Pseudo Genes (frameshifted)       :: 21 of 55
            Pseudo Genes (incomplete)         :: 28 of 55
            Pseudo Genes (internal stop)      :: 16 of 55
            Pseudo Genes (multiple problems)  :: 8 of 55
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9425
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941466-rid12468953.denovo.111"
                     /strain="01A10CD0081"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            complement(303..1037)
                     /locus_tag="KR231_003462"
     CDS             complement(303..1037)
                     /locus_tag="KR231_003462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 2-thiocytidine(32) synthetase TtcA"
                     /protein_id="HBH0005791.1"
                     /translation="MSIQKLLSKARKAIQDFDMIQENDKIAVGLSGGKDSLTLLHILK
                     SYQRFSPQNFELIAITLNTGGVDNSPLDKLCKEINVPFYEFQTDIKEIVFDIRQEKNP
                     CALCANLRRGALNDNAKKLGCNKVALGHHKDDAIETFLMSMFYEGRVNCFSPKTYLDR
                     QDLTVIRPMVYIEEYMTKKISKDSNYPIITNPCPANGHTRREYIKNLIANLNKEMPDF
                     KRNVFGALNNSEKLFIWDKEKIKNFK"
     gene            1162..1878
                     /locus_tag="KR231_003463"
     CDS             1162..1878
                     /locus_tag="KR231_003463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M15 family metallopeptidase"
                     /protein_id="HBH0005792.1"
                     /translation="MKKFKLIGAIILVVFISVFISKDRLLKKDKDPIVAAQHDSEQDV
                     EANSQNKNHSNSISNILLVNKTNGISKNYTPENITKVNIPFVEEATEEEKQMAGEPAK
                     AVEDLVKQANSEGIQFLGSSAYRSYDTQLDTYTRRVKSQGREKADAYVAKPGYSEHQT
                     GLCIDLTNPERWFVGSTKEAKWLAENAHKFGFIIRYPEGKEDITGTAYEPWHIRYVGK
                     DAAEEIYSKGLTLEEYLQNK"
     gene            2012..2704
                     /locus_tag="KR231_003464"
     CDS             2012..2704
                     /locus_tag="KR231_003464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011948339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBH0005793.1"
                     /translation="MNNTVLVVDDEKEIRDLIEIYLLNSGYNVIKAEDGKEALDILKK
                     ENIHLMILDIMMPKMDGIEVCRKVRESLNIPILMLSAKSEDMDKIQGIMTGADDYLTK
                     PFNPLELTVRVKSLIRRAYYFSGANNEDKDVIKVGVVIIDKEKHSVTVAGNEIILTSR
                     EFDILYLLANNKGRVYSTEEIFEKVWKEKYYQSNNTVMVHMSRIRDKIEKYTDGEKII
                     HTVWGVGYKIEK"
     gene            2694..3875
                     /locus_tag="KR231_003465"
     CDS             2694..3875
                     /locus_tag="KR231_003465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HBH0005794.1"
                     /translation="MKNKSLLNHMFRPILDLIISCALTSMLILTSMYIIKSLYVNSDM
                     SVVNQLVYQARDFRSLIGYDLFYPFLFTITSLAIYSIISYKRNKQIVDFIRKTNRKNQ
                     KLEIIKSAVNLMDEGNLEKSIDIEYDLDILKDKEKDDIDELAHKINNIVHQLRNITIE
                     ERQAQQTKTDLITNVSHDLRTPLTSIMGYLGVIEEGKYKDEVQMMYYVDIAYEKSKNL
                     NVLINDLFELTKMQNNTIKLNKIEINLVELLSQVVSQFEIYFKQEFMVSRINFNEEKL
                     IVKADPNKLVRAFENLITNAVKYGKDGHYVDIVTEKKEDMAVVKVINYGEPIPVLDLP
                     NIFDRFYRVEKSRNRNVGGSGLGLAITKNIVNLHDGEITVSSDKYQTVFEVQLPIIQS
                     A"
     gene            4157..4612
                     /locus_tag="KR231_003466"
     CDS             4157..4612
                     /locus_tag="KR231_003466"
                     /EC_number="4.4.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-ribosylhomocysteine lyase"
                     /protein_id="HBH0005795.1"
                     /translation="MEKVESFKLDHTKVKAPFVRKCSVLDGVKGDKVTKFDLRFLQPN
                     VESFGTAAMHGLEHLLATYLRDTLDGVIDLSPMGCRTGFYLILWGDVDAKTVKIGLEE
                     ALKKVLESDKMPAATAIECGNYRDLSLFGAKEYAKDVLDKGFSLNIYGE"
     gene            4602..5327
                     /locus_tag="KR231_003467"
     CDS             4602..5327
                     /locus_tag="KR231_003467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Vitamin B12 dependent methionine synthase,
                     activation domain protein"
                     /protein_id="HBH0005796.1"
                     /translation="MENNLIGREDISINQSEVLRYLQYRGQEIDKDLKYTIDECVAIT
                     KNKINPRYLSRIYPIRINKDNVVELEGTNLTLESKYVYELLKECNECVIMAATIGIDI
                     EKEIRRHSYSNLTKGLIIDSCGTTAIEEVCDIVQNNLEKVFLKQDKFITMRYSPGYGD
                     LPIEKNIDILNVLNAQKQIGLTITSNGIMIPRKSVVAIIGISNTRINKSKKEKSCENC
                     KNYRNCTYRKGANSCGNKTISEK"
     gene            5299..7680
                     /locus_tag="KR231_003468"
     CDS             5299..7680
                     /locus_tag="KR231_003468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homocysteine S-methyltransferase family protein"
                     /protein_id="HBH0005797.1"
                     /translation="MEIRQYLKNNILIFDGAMGTMLQQKGLKLGENPEVFGLQNPDKL
                     IEIHTAYLEAGSNVILTNTFGCNELKLDSKYTVEEVIDNAVLVARKAIENVDNTKPRY
                     VALDIGPIGEMLEPMGTLSFDKAYEIFKRQVLQGVKSGVDVIVIETMMDLYEAKVAVL
                     AAKENSDLPIFCTMTFDEGGRSFTGCMPECMVATIEGLGVDAIGVNCSLGPKQLLPIV
                     EKIASRATVPVMVQANAGLPNIVDGEAIYDVDAKEFFEGVKKFVEVGATIIGGCCGTN
                     PSFIKEISENINSVTKGCIEKIDKCVVCSPSKFVEVQSPTVVGERLNPTGRKSLQEAL
                     KNENVDYAINLGLEQVNAGAQILGVNVGLPEIDEKKLMPKLIREIQAVVDTPLQVDSS
                     NVEALEQGLRYYNGRTIVNSVNGKEESLESILPIVKKYGSCVVGLTLDEKGIPKKAEE
                     RFEIAKRIVNRAVSYGIKPKDIFIDCLSLTVSAQQEEAIETIKAITMVKTLGVKTILG
                     VSNISFGLPNRKALNASFLTLALGAGLDLAIINPNEYSMMEAINSFKILNNTDKGCIN
                     YINQYSNINNSKKSDSSTKIDKDLPLDILVERGLKDEAKNVTLNLLKEKDENYILDEI
                     LIPALDKVGKRYDSGDIFLPQLIQSAETVKVSLNTIKETLLSKSSNNVSKGKIIVATV
                     KGDIHDIGKNIVKIMLENYGYEVIDLGKDVPIEEVVEVAKKRNIKLVGLSALMTTTVQ
                     SMKDTIQALRDNEINAKVFVGGAVLTEEYAEEMGADYYSKDAKSAVEIAKLNF"
     gene            complement(7885..9114)
                     /locus_tag="KR231_003469"
     CDS             complement(7885..9114)
                     /locus_tag="KR231_003469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase"
                     /protein_id="HBH0005798.1"
                     /translation="MNLNRNLEKYAELAIKVGVNIQPGQILLIKSPIECADFARNALK
                     EAYKCGAKNVYIEWSDEESTLIKYLYAPDEAFHEFPKWTAEQYVDIAKEGGAFLSVYA
                     QNPDLLKDVDPERVANFQKASGKALKEWRSYTLTDKCKWNIVSVPTKDWAKKVFPNLS
                     EDKAIEKLWDAIFKCSRVDGQDPIKAWEEHNENLKSKMDFLNKNNFKTLKYKSSKTDL
                     TLDLPKGHVWLSGASKDPNGISFNPNIPTEEIFGMPHKFKVNGTVYSTKPLVYGGNII
                     DNFFLTFKDGKIIDFSAEKGLDTLEKLIETDEGSHYLGEVALVPYNSPISNTDIIFYN
                     TLYDENASCHFAIGSAYKTCLEGGNNLKDEELDEHGVNDSLTHVDFMIGSADMDIIGE
                     TYDGKQIQIFKNGNWAF"
BASE COUNT         3723 a         1071 c         1572 g         3059 t
ORIGIN      
        1 tttaatatta taatctaaca taaaatattt agaaaatata attttgcttt ttataatatg
       61 tagatgtata tactgtaaaa atggattaaa ccagtagatt gaatgaatta atagattaaa
      121 ttaatatata aaatatttaa gttataatta atgtattaga caaaataaat actattaaga
      181 actattaaaa tatagattaa agataataac atataataaa taaaaaagta agattgtgta
      241 gattatataa agattattta caattaatac aatcttgctt ttttatttaa aaattttaat
      301 tattatttaa aattttttat cttctcttta tcccatataa acaatttctc agaattattt
      361 aaagcaccaa atacatttct tttaaaatca ggcatctctt tatttaaatt agcaataaga
      421 ttttttatgt actctctcct agtatgacca tttgcagggc agggatttgt gataatagga
      481 tagttagaat cttttgaaat tttcttagtc atatactctt ctatgtaaac cataggtctt
      541 ataactgtta aatcctgtct gtctaggtat gtctttgggg aaaaacaatt tactctaccc
      601 tcataaaaca tagacattaa aaatgtctca attgcatcat ctttatgatg accaagagct
      661 actttattac atccaagttt tttagcatta tcgttcaaag cacctcttct taaattagca
      721 cacaatgcac aaggattctt ttcttgtctt atatcaaata caatttcttt tatgtcagtt
      781 tgaaattcat aaaaaggaac atttatttct ttacacaatt tatctagtgg agaattatca
      841 acacctccag tatttaatgt tatggctatc aattcaaagt tttgtggaga aaatctttga
      901 taacttttaa gtatatgaag tagagttaaa ctatcttttc caccagaaag tccaaccgca
      961 attttatcat tttcttgtat catatcaaaa tcttgtatag ccttacgagc tttacttaga
     1021 agtttttgta tagacatttt atcaccatcc tttaaaaata ttaaatttaa gatttattta
     1081 agatttactt ataaaatact taagtcttat actctaaaat taacattata gcaaacataa
     1141 caaaaaggag aagatttaat tatgaaaaaa tttaaattaa taggagccat tattttagta
     1201 gtatttataa gtgtatttat atctaaagat agattactta agaaagataa agatccaata
     1261 gtagctgctc aacatgattc agaacaagat gttgaggcaa attctcaaaa taaaaatcac
     1321 tcaaatagta tatcaaatat attattggta aacaagacaa atggaattag caaaaactat
     1381 actcctgaaa atattactaa ggtaaacata ccttttgttg aagaagcaac agaggaagaa
     1441 aaacaaatgg caggagaacc tgcaaaggca gttgaagatt tagttaagca agctaattca
     1501 gaaggaatac agtttttagg gtcttcagca tacagatctt atgatactca actggatact
     1561 tatacaagaa gggtaaaatc tcaggggcga gaaaaggcag atgcatatgt agcaaagcct
     1621 ggttacagtg agcaccaaac tggactttgt attgatttaa caaatccaga aagatggttt
     1681 gttggaagta caaaagaagc taaatggttg gcagaaaatg ctcacaagtt tggatttata
     1741 ataagatatc ctgaaggtaa agaagatata acaggtacag catatgaacc atggcatatt
     1801 agatatgttg gtaaggatgc tgctgaggaa atttattcaa aaggattaac tttagaagaa
     1861 tatttacaaa ataaataata taaatgtgta aataatttgt attatattgg aaatttagaa
     1921 attaataaat ttatagatta cactaactaa aatatagtat aattttatat gaataaagct
     1981 atatacaaag attaagttag gatgtgtaaa aatgaataat acagttcttg ttgtggatga
     2041 tgaaaaggaa ataagagacc ttatagagat atatctttta aatagtggat ataatgtaat
     2101 taaagctgaa gatggaaaag aggctctaga tattttaaaa aaggaaaata ttcatttaat
     2161 gatattggat ataatgatgc ctaaaatgga tgggatagaa gtttgtagaa aagttagaga
     2221 aagtttgaat ataccaatac ttatgttaag tgcaaaatca gaagacatgg ataaaataca
     2281 agggataatg actggtgcag atgactattt gacaaaacca tttaacccac ttgaacttac
     2341 tgtgagagtg aagtcgctga ttagaagagc atattatttt agtggtgcta ataatgaaga
     2401 taaagatgtc ataaaggttg gagtagtaat tatagataag gaaaaacata gtgtaacagt
     2461 ggctggaaat gaaataattt tgacatcaag agaatttgat atattatatt tactagcaaa
     2521 taataaaggc agagtatata gtacagaaga aatatttgaa aaggtatgga aagagaaata
     2581 ttaccaatct aataatactg taatggttca tatgagcaga ataagggata aaattgaaaa
     2641 atatacagat ggagaaaaaa taattcatac tgtatgggga gtaggatata aaattgaaaa
     2701 ataaaagttt attaaatcat atgtttcgac ccatattaga tcttataata agctgtgctt
     2761 taacttcaat gcttatttta acaagtatgt atataataaa atcattatat gtcaatagtg
     2821 atatgtctgt agttaatcaa cttgtatatc aagcaagaga tttcagaagt cttatagggt
     2881 atgatttatt ttatccattt ttatttacaa tcacatcatt agcaatttat tccattatat
     2941 cgtacaagag aaataagcaa attgtagatt ttataagaaa gactaataga aaaaatcaaa
     3001 aattagaaat cattaaaagt gctgtaaatt taatggatga aggtaactta gaaaaaagta
     3061 tagatattga gtatgattta gatatattaa aggataaaga aaaggatgat attgatgaac
     3121 tagcacataa aatcaataat atagtccatc aacttagaaa tataactatt gaagagagac
     3181 aagctcagca gacaaaaaca gatttaataa caaatgtgtc acatgactta agaacacctt
     3241 tgacatccat aatgggttat ttaggagtga tagaagaagg taagtataaa gatgaagttc
     3301 agatgatgta ctatgttgat attgcatatg aaaaatcgaa aaatttaaat gttcttataa
     3361 atgatttgtt tgaattgact aaaatgcaaa ataatacaat aaaattaaac aaaatagaaa
     3421 taaatttagt agagttatta agtcaagtag tatctcaatt tgaaatttat tttaaacaag
     3481 aatttatggt tagtagaatt aattttaatg aagaaaaatt aattgtaaaa gctgatccaa
     3541 ataaattggt aagagcattt gaaaatctta taactaatgc tgtgaaatat ggaaaagatg
     3601 ggcattatgt agatatagtc acagagaaaa aggaagatat ggcggttgta aaagtgataa
     3661 attatgggga accaattcca gtgttagatt taccaaatat atttgataga ttttatagag
     3721 ttgaaaaatc gagaaataga aatgttggag gttctggatt gggtcttgcg attacaaaaa
     3781 atattgtaaa tttacatgat ggagaaatta ctgtttcaag cgataaatat caaactgtgt
     3841 ttgaagtaca actgccaata atacaatcag cttagttata aaataaaagt acgattatgt
     3901 gatataaata ttataacaat aaagtgttta caaaaataaa aaagtaatat ataatttaag
     3961 tcagtttaat aagatactta tcaagagtta ggggagagag ttagctcagt gatcctatac
     4021 caacctttta tcaggtggtc ctgctaacaa cgatgagatg acttgaaata atatactctt
     4081 cttatcaata atagatagga agagtttttt ttagaattaa tgtaacaaat tttaaagtat
     4141 aatggaggat taaataatgg aaaaagtaga aagttttaag ctagaccata caaaagtaaa
     4201 agctcctttt gtaagaaagt gtagtgtact tgatggagta aagggagata aagtaactaa
     4261 atttgacttg agatttttac agccaaatgt agaaagtttt ggaactgctg ctatgcacgg
     4321 tttagagcat cttttagcta cttatttaag agatacatta gatggtgtaa tagacttatc
     4381 tccaatggga tgtagaacag gattttattt aatactatgg ggagatgtag atgccaaaac
     4441 agttaagatt ggtttagaag aagcattaaa aaaagttctt gaatcagata aaatgccagc
     4501 agctacagct atagaatgtg gaaactacag agacttatct ttatttgggg caaaggaata
     4561 tgcaaaagat gttttagata aaggattttc tttaaatata tatggagaat aatttaattg
     4621 gaagagaaga tataagcata aatcaaagtg aagttttaag atatttacaa tacagaggtc
     4681 aagagataga taaagacctt aaatatacta ttgatgaatg tgtagctata actaaaaata
     4741 aaataaatcc tagatattta tctaggattt atcctattag aataaataaa gataatgttg
     4801 tagaattaga gggaacaaat ttaacattag agagtaaata tgtatatgaa cttttaaaag
     4861 aatgtaatga gtgtgtaatt atggcagcta ctatagggat agatatagaa aaagaaataa
     4921 gacgacactc ttattcaaat ttaacaaaag gactaataat tgattcatgt ggaacaacag
     4981 caatagaaga agtgtgtgac attgttcaaa ataatttaga aaaggttttt ttaaagcaag
     5041 ataaatttat aactatgcga tatagcccag gatatggaga tttaccaata gaaaaaaata
     5101 tagatatatt aaacgttttg aatgctcaaa aacaaatagg tctaacaatt acttctaatg
     5161 gaattatgat accgagaaag tcagtagtgg ctattatagg tatttctaat acaagaataa
     5221 ataaatctaa gaaagaaaag tcgtgtgaaa attgtaaaaa ctatagaaac tgtacatata
     5281 gaaagggagc gaactcttgt ggaaataaga caatatctga aaaataatat attaatattt
     5341 gatggtgcaa tgggaacaat gcttcaacaa aaagggttaa agttaggtga aaatccagaa
     5401 gtatttggtc ttcaaaatcc agataaactt atagaaatac atacagcata cttagaggca
     5461 ggttcgaatg taattcttac aaatactttt ggatgtaatg aactaaaatt agatagtaag
     5521 tatactgtag aagaagtgat tgacaatgct gttttggtgg ctagaaaagc tatagaaaat
     5581 gtagataata ctaaaccaag atatgtagct ttagatattg gtcctatagg agaaatgcta
     5641 gagcctatgg gtactttaag ttttgataaa gcatatgaaa tatttaaaag acaagtacta
     5701 caaggcgtta aatctggagt tgatgtaata gtaatagaga ctatgatgga tttatatgaa
     5761 gctaaagtag ctgtattagc agcaaaagaa aactctgatt tacctatttt ctgtactatg
     5821 acatttgatg aaggtggaag aagttttact ggatgtatgc cagaatgtat ggtggctact
     5881 atagaaggtc taggtgtaga tgcaatagga gttaattgtt cattaggacc taaacaactt
     5941 ttaccaatag ttgaaaaaat agcatcaaga gctacagtcc ctgttatggt tcaagcaaat
     6001 gcaggtcttc caaatatagt tgatggagag gctatatatg atgtcgatgc aaaagaattt
     6061 tttgaagggg ttaaaaagtt cgttgaagtt ggtgctacta taataggtgg atgttgtggt
     6121 acgaatccaa gttttataaa agaaatatct gagaatataa attctgttac aaagggatgt
     6181 atcgagaaaa ttgataaatg tgtagtctgt tcaccatcaa aatttgtgga agtacaatcg
     6241 cctacagttg ttggagaaag attgaatccc acaggtagaa aatctctaca agaagcatta
     6301 aaaaatgaaa atgttgatta tgctataaat ttaggtttag agcaagtaaa tgctggagca
     6361 caaatacttg gagtaaatgt tggtcttcca gagattgatg aaaaaaaact aatgccaaaa
     6421 ttaataagag agattcaagc agtagtagat acacctttac aagttgattc ttccaatgta
     6481 gaggccttag agcaaggact tagatattat aatggtagaa caatagtaaa ctctgtaaat
     6541 ggcaaagagg agtctttaga aagtatatta ccaatagtta aaaagtatgg ttcatgtgtg
     6601 gttggactta cacttgatga aaaggggata cctaaaaagg ctgaagaaag atttgaaata
     6661 gcaaaaagga tagttaatag agcagtttct tatgggataa aaccaaaaga tatatttata
     6721 gactgtttat cattaactgt ttcagcacaa caagaagaag caatagaaac tataaaagct
     6781 ataacaatgg taaagacact aggagtaaaa actatattag gtgtttcaaa tatttcattt
     6841 ggtcttccaa ataggaaagc acttaatgct tcttttctaa cattagcttt aggggcaggg
     6901 cttgatttag caattataaa tccaaatgaa tatagtatga tggaagctat caattctttt
     6961 aaaatattaa ataacacaga taaaggatgt ataaactata taaatcaata tagcaatata
     7021 aataattcaa aaaaatcgga ttcatctaca aagattgata aagatttgcc cttggatatt
     7081 ttagttgaaa gaggattaaa agatgaagca aaaaatgtaa cactgaatct tttaaaagag
     7141 aaggatgaaa attatatatt agatgagatt ttaattcctg ctcttgataa agtaggaaaa
     7201 agatatgata gtggagatat atttttacca caattgattc aatcagcaga aacggtaaaa
     7261 gtttcattaa atacaataaa ggaaacttta ttaagtaaaa gtagcaataa tgtatccaaa
     7321 ggaaaaataa tagttgctac agtaaaaggt gatatccatg atattgggaa aaatatagta
     7381 aaaataatgc tagaaaatta tggatatgaa gttatagatt taggtaaaga tgtccctatt
     7441 gaagaagtag tggaagttgc taaaaagaga aatataaaat tagtaggatt aagtgcactt
     7501 atgactacga ctgttcaaag tatgaaagat acaattcagg cactgagaga taatgagata
     7561 aatgcaaagg tatttgtagg aggtgcagtt ttgacagaag aatacgctga agaaatgggt
     7621 gctgattatt attcaaagga tgcaaagtct gctgttgaaa tagcaaagtt aaatttttag
     7681 catataaatt aaaataaagg ttttactaaa taggatattt tatatataat ataaatataa
     7741 gttttagata cttatgttta aaacaatagg aattaatcta taataatgag attaattaat
     7801 ataaaaaata tttatcatca acattaaaaa gggctgggaa gtctggtata acttccatca
     7861 gcccttttta gttaaaatca tatgttaaaa agcccaatta ccatttttaa aaatctgtat
     7921 ttgctttcca tcataagtct caccaataat atccatatca gcagaaccaa tcataaaatc
     7981 tacatgtgtt aaactgtcat ttacaccatg ttcatccaat tcttcatctt ttaaattatt
     8041 tccaccttcc agacaagtct tataagcaga accaattgca aagtggcaag aagcattttc
     8101 atcatataga gtattataaa aaattatatc cgtattggat attggtgagt tgtatggaac
     8161 aagagcgact tctcctaaat aatgagagcc ttcatccgtt tcaataagtt tttctagtgt
     8221 atctagtccc ttttcagcag agaaatctat tattttacca tctttaaatg ttaagaagaa
     8281 attgtcaatt atgtttccac cataaacaag aggttttgta ctataaacag ttccatttac
     8341 tttaaactta tgtggcattc caaaaatctc ttcagttgga atattcggat taaaacttat
     8401 tccattaggg tctttggatg ctccacttag ccaaacatga ccctttggca agtctagagt
     8461 caaatcagtt tttgaggatt tatattttaa agttttaaag ttatttttat ttagaaagtc
     8521 cattttagat ttaagatttt cattatgttc ttcccatgct tttatagggt cctgaccatc
     8581 tactcttgaa catttaaata tagcatccca cagtttttct attgctttat cttctgataa
     8641 atttggaaac actttttttg cccaatcttt tgttggcaca gagactatat tccatttaca
     8701 tttatcagtt agagtgtaag aacgccattc ttttaaagct tttccagatg ccttctgaaa
     8761 atttgcaact ctttcagggt caacatcttt taataaatct ggattttggg catagactga
     8821 taaaaatgcc ccaccttctt ttgctatatc tacatattgt tctgctgtcc atttggggaa
     8881 ctcatgaaat gcttcatctg gagcatataa gtatttaata agagtacttt cttcatcaga
     8941 ccactctata taaacatttt tagcaccaca tttatatgct tctttaagtg catttcttgc
     9001 aaaatcagca cattctattg gtgactttat aagtagaatt tgacctggct gtatgttaac
     9061 tccaactttt attgctaatt cagcgtattt ttctaaattt ctatttaaat tcatatttat
     9121 cctcctatat ttttaatatt gaataactta taaagtatta taacattact tatgttttta
     9181 atattgaaca acttataaaa tattataact ttacttagat tttgggtcat attcaaaata
     9241 tttatacttt atagattgag aaataaaaaa aatattttaa ttaaaacaaa ttatgaggat
     9301 aacaaactta tttaagcagt atgttttttg ttgataataa tattaaagta gaaataaaaa
     9361 tactttttta gtgaaaagct atacaagaat accgaaaaaa acttataata taataatgag
     9421 ataga
//
LOCUS       DAEPHU010000112         9390 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 01A10CD0081
            SAMN05941466-rid12468953.denovo.112, whole genome shotgun sequence.
ACCESSION   DAEPHU010000112 DAEPHU010000000
VERSION     DAEPHU010000112.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941466
            Sequence Read Archive: SRR6291087
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 9390)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9390)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068158.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 22:43:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,892
            CDSs (total)                      :: 3,805
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 87
            rRNAs                             :: 8, 1, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 55
            CDSs (without protein)            :: 55
            Pseudo Genes (ambiguous residues) :: 0 of 55
            Pseudo Genes (frameshifted)       :: 21 of 55
            Pseudo Genes (incomplete)         :: 28 of 55
            Pseudo Genes (internal stop)      :: 16 of 55
            Pseudo Genes (multiple problems)  :: 8 of 55
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9390
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941466-rid12468953.denovo.112"
                     /strain="01A10CD0081"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            complement(462..4187)
                     /gene="cbpA"
                     /locus_tag="KR231_003470"
     CDS             complement(462..4187)
                     /gene="cbpA"
                     /locus_tag="KR231_003470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="collagen-binding adhesin CbpA"
                     /protein_id="HBH0005799.1"
                     /translation="MQQKCKKKALSMILSISMGLGSVASFNASNTFADTIEESTNAGN
                     AEGDTNAGNAEGDTNAGNAEGDTNAGNAGGDANAGNAGGDANAGNAGGDANAGNAGGD
                     ANAGNAGGDANAGNAEEDSNAGNAEGDANAGNAEEDANAGNAEEDSNAGNAEEDMNAL
                     VVEEATAEDPTSVGDFKISGGEINVDFKFASGVLTILSGKQMTIQNNNPNTPTTHRIV
                     IPKDVKAELIFDGVNIKTASNSPFTLTPDKDGGAYAHVILQDGSENKLESGDVYYPGM
                     RAGKGTTLTIDDSVVNRDIEGEFIVPEGGKIPRDVTLENGDKLKKGDRLTLLDSNNRG
                     SLKVVGNYYSAGIGGGNTESGGNIIINGGAITAIGQESSRNTGYGAGIGGGGNGSGGD
                     ITINGGTITAKGAYHGAGIGGGYYTTTKNALSPSVVDPSTGSGYSGNITINGGLSYSY
                     GGAHGSAFGDGCVNPGTNRGYRILVTGGTILPYMTGVGDWIFDLSATTGDVIVTGGSL
                     KATTFKSLGGAVAYGDLEKKTKVFMNKISLKYLGQDKVSTTLVDDFKMLIDGKIYPYG
                     APSYTDDQGVLYLWFSDQFKGSEVSVNLVVIDKITGGNIKPDDFYVKDIGSGSQFLKQ
                     YEEFTIDDTPPYLIIKRYDGLPFEEDVEKLFLDWILKDGGIPIITPKGEKLTDKKFMT
                     ISSQRLNEETMEPDTNLGSDDLTKQVDAGKYQLSITSTQFSNVYPFNEAYWGHRAYYK
                     AEIIPADTETSLVVEESKAKTDVFKPTDTFTLNVTISPDKKEGPDCASPRGYVQFYIN
                     GKEYKDPVELKTHNKGSESHNYSTASIEWRPLDSNHHIFTTEQTITVKYIGDDINYIE
                     GSEDEKKLKLDMTNVDVDGDGIPDINIDTDGDGRPDINIDTSGDWKPDINIDTDNTGE
                     WKPSTEGGNGDGIWKPDKNIDTNGDGNPDTDYNRPAIDTDNDGVDDYWKPDKNVDTGS
                     GGYDTGNPNLNKPDPDNGGNSKPDPDNGGNSKPDSGNGGNSKPDSGNGGNSKPDSGNG
                     GNSKPDSGNGGNSKPDPDNGGNSKPDPDNGGNGKPDPDNGGNSKPDPDNGGNSKPDPD
                     NGGNSKPDIDTDGDGKPNINIDIDGDGKPDINIDTDGDGKPDINIDIDGDGKPDINID
                     IDGDGKPDINIDIDGDGKPDINIDTDGDGKPDINIDTDGNGKPDINIDTDESLDSNVG
                     QNVQTGDQSNIMLDLALMFISLFFLIKNLTNKYLRRK"
     gene            4456..5028
                     /locus_tag="KR231_003471"
     CDS             4456..5028
                     /locus_tag="KR231_003471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427525.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class B sortase"
                     /protein_id="HBH0005800.1"
                     /translation="MEKLVKILINIICIIALTFSSLSIYIKLSEYKKADEVYTELREN
                     TINNSKHQELYDKNNDYRFWLKINNVNINYPVVQGYNNDFYLTHDFYKNYLPLGSIFM
                     DYRNNFENDKSLIVYGHYMKNKTMFGQLENYTDEVFFKENNLVEINYKVQTYTYEIFS
                     VYTADLINRDYLSIHFNNNDEFKYSLNYIT"
     gene            complement(6028..7653)
                     /locus_tag="KR231_003472"
     CDS             complement(6028..7653)
                     /locus_tag="KR231_003472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012100074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA cytosine methyltransferase"
                     /protein_id="HBH0005801.1"
                     /translation="MYNVIDLFAGAGGLSLGFEMTKKFNMVAFVEKNDNAAKTYLENH
                     PSVKRYCDIKRLDFQDILNSVDKIDVVIGGPPCQGFSNANRQKRKIINGNNELVKLYV
                     DAIDKLKPNVFVMENVKTISSNKHSFYLTKKDKNHIINNLKLNIYNKDSVLYDRTEYI
                     NELFNIISIEDIESYIISNIDLKNLKIIIKKKKDICDYLNKISNYKKVKSTIEKLETR
                     GKMPKWYLELINKVKNILENMLYNRNLSDEQIFYLNLFLDIQNLFLGIYELKSESVIF
                     ENTLDDNKIIAKMDTYIIIDYINASFEYLGYVLNGSALNSIDYGVPQNRERFVLIGAK
                     KDFLKNKKIETPKPIVGENYVTVRDAIGDLAEYEASKGSMDYCFEKNSNNIEKDFYRK
                     IILDSNKIYNHVCTDTRNIALKRFEYINQGNNFHSLPDELKGTYADPERTQNTIYKRL
                     VYDKPSDTVVNVRKSMWIHPIKNRAVSAREAARLQSFPDSYKFLGTKDSVYQQIGNAV
                     PPLLGRVVAEKILNLFNDEPNEYLRDVFEALDG"
     gene            7965..>9390
                     /locus_tag="KR231_003473"
     CDS             7965..>9390
                     /locus_tag="KR231_003473"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0005802.1"
                     /translation="MLTTNIHYILDNDICEIYFNKQRLTNSKYYQDNINVLNYIINEK
                     NNNLIINYNDKYIYAIYLLNIAINSYLNNTLNPNNHILTKLDKGMPLLYKGQIVIFKN
                     INNTHITLGHKNKTDTTLIPIDSAYMLITYNGHLEVNSMGKTPASKTFQTKNVLSSLG
                     FSDLKNMTGVINDSTLIILPCKDDISDLVSNIKIKDINNTYKFTELFPCSYISSTGAE
                     TDYPGNHAKQIPLLKFTTNISSAFEIIKSDKSIKNVFIIGDYPIYKHINDFERILNRK
                     RIESVNIVTSNSNISNILDLPNIDNLNIYSWSKDVLLTYSQDFENTSTFQKLWLDKLI
                     NKNICTTSVDSNISDLIHQARKSLYYISKYDFDISIKNSLMMCSYSLLKILENTPFNL
                     DFLEETIKLLNLNIATPSAKLENIKYLISSTSPDLELSALFDDVIVKFERIINELSDN
                     NTKFNTLNKLVSSYKYKTFTPNTPV"
BASE COUNT         3133 a         1618 c          990 g         3649 t
ORIGIN      
        1 tattaattta aaaaaatcta tttttatatc agatgggtat tgttttttat aaaactgaaa
       61 aaatcaccta atagaatcta tgatttttta acataacctc cataaattag taccaattat
      121 cacttcaaat tcaaattttt atctgaagaa tatacaatca tatttccata ctcaacataa
      181 tattgagtgt ttggcttgta tttacaaatt attattctaa caaaaacaac tatacataga
      241 ttaaaatcac cttctaaaca taattattaa aatttaatta atgatatcaa ttccattaat
      301 ctcttttaat aaaaaattct cttttctata tgaaaattat ttcaaaactt ttaagttaaa
      361 tacaaaaatg actataaata gatttttatt tacacaaatc tatttatagt cactatagtt
      421 tatccaataa aataataaaa taaatatgta cacaataaat gttatttacg tcttaagtat
      481 ttatttgtta gatttttaat taaaaaaaac aagctaatga acattaatgc taaatctagc
      541 attatattac tttgatctcc tgtttgtaca ttttgaccta cattactatc taaactttca
      601 tctgtatcta tatttatatc tggttttcca ttcccatctg tatctatatt tatatccggc
      661 tttccatccc catctgtatc tatatttata tccggttttc catctccatc tatatctata
      721 tttatatctg gttttccatc tccatctata tctatattta tatctggttt tccatctcca
      781 tctatatcta tatttatatc tggttttcca tctccatctg tatctatatt tatatctggt
      841 tttccatctc catctatatc tatatttata ttcggttttc catccccatc tgtatctata
      901 tctggtttgc tatttcctcc attatctggg tctggtttac tatttccacc gttatctgga
      961 tccggtttgc tatttcctcc attatctgga tctggtttac cattgccacc gttatctgga
     1021 tctggtttgc tatttcctcc gttatctgga tccggtttgc tatttcctcc attacctgaa
     1081 tccggtttgc tatttcctcc attacctgaa tctggtttgc tatttcctcc attacctgaa
     1141 tccggtttgc tatttcctcc attacctgaa tctggtttgc tatttcctcc attatctgga
     1201 tccggcttgc tatttcctcc attatctgga tctggcttat ttagatttgg attacctgta
     1261 tcataacctc ctgagccagt atctacattt ttatcaggct tccaataatc atctactcca
     1321 tcattatctg tatctattgc tggacgatta taatctgtat cagggtttcc atctccattg
     1381 gtatctatat ttttatcagg tttccaaata ccatctccat ttccaccttc tgtactaggc
     1441 ttccattcac ctgtattatc agtatctatg ttaatatctg gcttccaatc accactcgta
     1501 tctatattga tatctggcct tccatcacca tcagtgtcta tatttatatc cggtattcca
     1561 tccccatcta catctacatt tgtcatatct aactttaact tcttttcatc ctcactacct
     1621 tcaatgtaat ttatatcatc tccaatatat tttacagtaa tagtttgttc agtagtaaaa
     1681 atatgatgat tgctatctaa aggtctccat tcaatagatg cagtactata attatgactc
     1741 tcactaccct tattatgagt ttttaattct actggatctt tatattcctt tccattaata
     1801 tagaattgta cgtaacctct tggagaggca caatctggtc cttctttctt atctggtgaa
     1861 atagtaacat ttaatgtaaa cgtatctgtt ggtttaaaaa catcagtttt agctttagac
     1921 tcttctacaa ctaatgaagt ttctgtatca gcaggaataa tttctgcctt ataatatgct
     1981 ctatgccccc aataagcttc attaaaagga tatacatttg aaaactgtgt tgatgtaatg
     2041 cttaattgat attttccagc atcaacttgc tttgtaaggt catcacttcc taaatttgta
     2101 tctggttcca ttgtttcctc atttaaacgt tgagaactaa tagtcataaa ttttttatct
     2161 gtgagttttt cacctttagg agtaattatt ggaatacccc catcttttaa tatccaatct
     2221 aaaaataatt tttctacatc ttcttcaaat ggtaatccat catatctttt aataatcaaa
     2281 tatggtggag tatcatcaat agtaaattct tcatattgct ttaaaaattg agaacctgaa
     2341 cctatatctt taacataaaa atcatctggt tttatatttc ctccagtaat tttatctata
     2401 acaactaaat taacagatac ttcagatccc ttaaattgat cagaaaacca taagtaaaga
     2461 accccttgat catctgtata actaggtgct ccataaggat aaatttttcc atcaattagc
     2521 attttaaaat catcaactaa tgtagtacta actttatctt gtcctaaata ctttaaagat
     2581 attttattca taaaaacttt tgttttcttt tctaaatcac cgtatgcaac tgctccacct
     2641 aaacttttga atgttgttgc ttttaatgaa ccacctgtta ctataacatc tcctgttgta
     2701 gcacttaggt caaaaatcca atctcccact cctgtcatat aaggtaaaat cgttcctcca
     2761 gttacaagta tacgatatcc tctatttgtt cctggattaa cacatccatc cccaaatgca
     2821 ctaccatgtg cacctccata tgaataggaa agtccaccat taattgtaat atttccacta
     2881 taaccagaac ctgtgctagg atctactact gagggactta atgcattctt tgttgttgta
     2941 tagtatcctc cacctattcc agctccatgg tatgcacctt tagcagttat agtaccacca
     3001 ttgattgtga tatctccacc actaccatta ccgcctccac ctattccagc tccatatcct
     3061 gtattacgac tcgattcttg acctatagca gttatagcac caccattaat aataatattt
     3121 cctccacttt cagtatttcc accgccaata cctgcagaat aataatttcc aacaactttt
     3181 aaacttcctc tattattact atctagtagt gtaaggcgat ctcctttttt taacttgtct
     3241 ccattttcta gagttacatc tctaggaatt tttccaccct caggaactat aaactctcct
     3301 tcaatatctc tatttacaac agaatcatca atagttagag tagtaccttt tcctgctctc
     3361 atacctggat aatatacatc acctgactct agcttgtttt cactaccatc ttgtaatata
     3421 acatgtgcat atgcaccacc atctttatct ggtgttaaag taaatgggct attagatgca
     3481 gttttaatat ttactccatc aaatattaat tcagctttta catctttagg tataacaatc
     3541 ctatgtgttg ttggagtatt tggattatta ttttgaattg tcatttgttt tccactaaga
     3601 atagttaaaa cgccacttgc aaatttaaaa tcgacattta tttctccacc actaatttta
     3661 aagtctccta cagatgtagg atcttctgca gtggcttctt ccacaactaa tgcattcata
     3721 tcttcttctg catttcctgc attagaatct tcttctgcat ttcctgcatt agcatcttct
     3781 tctgcatttc ctgcattagc atctccttct gcatttcctg cattagaatc ttcttctgca
     3841 tttcctgcat tagcatcccc tcctgcattt cctgcattag catcccctcc tgcatttcct
     3901 gcattagcat cccctcctgc atttcctgca ttagcatccc ctcctgcatt tcctgcatta
     3961 gcatcccctc ctgcatttcc tgcattagta tctccttctg catttcctgc attagtatct
     4021 ccttctgcat ttcctgcatt agtatctcct tctgcatttc ctgcattagt actttcttct
     4081 atagtatctg cgaaagtatt tgacgcatta aatgatgcta ctgatccaag tcccattgag
     4141 atacttaaaa tcattgatag tgctttcttt ttacattttt gttgcataaa ttccccctcc
     4201 ccttaataat ttttaatata cactgtatac atccttatat acactctaat aattcttaat
     4261 atacactgta tacatcctta tatgcactct aataattttt aatatatact taaaacttat
     4321 atttgtcaat gaatatactg tttttttcaa ccttatatat tataagtatt cattatttgc
     4381 taaataacta caataaaaat tttaattata taaaatttat ttaatttttt atataataat
     4441 actaaggggt aattaattga aaaactagta aaaatattaa taaatattat ttgcattatt
     4501 gcgctaactt tctctagcct ttcgatttac ataaaattat ctgaatataa aaaagctgat
     4561 gaagtatata cggaactcag agaaaacact atcaataata gcaaacatca agaactttat
     4621 gataaaaata atgattatag attctggctt aaaataaaca acgtaaatat aaactatcct
     4681 gtagtacaag gatataacaa tgatttctac ctaactcatg atttttataa aaattatctt
     4741 cctttaggta gtattttcat ggattataga aataattttg aaaatgataa gagtttaata
     4801 gtctatggtc attatatgaa aaataaaact atgtttggtc aactagaaaa ctatactgat
     4861 gaagtatttt tcaaagaaaa taacttagta gaaataaatt ataaagtaca aacttatact
     4921 tatgaaattt tttcagtata tactgctgac ttaattaaca gagattattt aagtatacac
     4981 tttaataata atgatgagtt taaatattct ttgaattata taacctaaaa atcagtacac
     5041 aaatctgata taaaggtaga tatttcagat aaaattataa ctttgtatac ttgtaactat
     5101 gaatttaaag atgctcttac tatagttcat gctaaattaa tttcaaaaaa gagacctata
     5161 agtaggtttg tgtaaatgca gacttatcta cagtcttttt tgaacgtaaa attggtaagt
     5221 atggaataat atttatatta aacttttgta ggcaaagaaa tgaaaaatca aagagaaata
     5281 attattacag atttagatta ccaagctgaa ttaagaaagt gtaaaactat ggaggatgta
     5341 gttggtgaag atagtatata atagcttaac ttataaatta tcttggtgat attaatgaag
     5401 tttcaaagta tatattattt attgatataa ataaaattaa atctgtttct aatagatgta
     5461 cctttgtttg gagacaaact attgaagaaa tataactaaa atgttgaagt agctacctga
     5521 ctttattttg aaatgcgaac aagattttgg cattaagata atttagaaag aatcactggt
     5581 acacaaggat gtgaacttag aatgaataga agtattcagg cataaggagc tttcacccaa
     5641 ataaaacata gtatgaactt taaaagaatt ctaatcaaag gcaatcaaaa tattctttca
     5701 gagtttatac ctgtagtgtt agcctatagt atttctaagt ttcacaaata agataatcat
     5761 taataaatgt agtatgtata ttcatcctct caaaaatatt ttttaatctt acactttgta
     5821 aattattcta ttttaaaatt gtatttttat acctttattt cttatgaccg ttttcaagct
     5881 caaattttgc ataaatataa attaatgaaa agcaagtaaa aaaagaactg tcgcacagca
     5941 atttaaaatt actcattcga cagtccttat ttcgtggatt aatgttggat aagaatcaca
     6001 agaataatac ccactatttt atttgaacta tccatctagt gcttcaaaca catctctaag
     6061 atactcattt ggttcatcat taaataaatt taatatcttt tctgctacta ctcgacctaa
     6121 taaaggtggt actgcatttc ctatctgttg atatacagaa tcttttgtac ctaaaaactt
     6181 ataactatca gggaatgact gcaatctagc cgcctctctt gcgctaacag ctctgttttt
     6241 aataggatgt atccacatag attttcttac atttacaaca gtatctgatg gcttatcata
     6301 tactagtctt ttataaatag tattttgagt tctttctgga tcagcataag ttccttttaa
     6361 ctcatctggc aaagaatgaa aattatttcc ttgatttata tattcaaatc tttttagtgc
     6421 gatatttctt gtatctgtac atacatgatt gtatatttta ttgctatcca atattatctt
     6481 tctataaaaa tctttttcaa tattattact atttttttca aaacaataat ccatactacc
     6541 tttagaagcc tcatattcag ctaaatcgcc tattgcatct cttactgtaa cataattttc
     6601 tccaactata ggcttaggag tttctatctt tttatttttt aagaagtctt tttttgctcc
     6661 tatcaataca aatctttctc tattttgagg tactccataa tcaattgaat ttagtgcact
     6721 tccatttaat acatatccta gatactcaaa ggatgcattt atataatcta ttataatgta
     6781 agtatccatt ttagctataa ttttattatc atcaagtgta ttttcgaaaa ttacagattc
     6841 agattttaac tcatatattc ctaaaaataa attttgaata tccaagaata agttcaaata
     6901 aaatatttgt tcatctgata aatttctatt atataacata ttttctaata tattttttac
     6961 tttatttatt aattctaaat accattttgg catttttccc cttgtttcca atttttctat
     7021 ggtagatttt actttcttat aattagatat tttatttaaa taatcacata tatccttttt
     7081 tttcttaata attattttca aattttttaa gtctatattt gatataatat atgattcaat
     7141 atcttctata ctaataatat taaataattc atttatatac tcagttctat catataaaac
     7201 actatcttta ttataaatat ttaattttaa attatttatt atatgatttt tatctttttt
     7261 agtcaaataa aatgaatgct tatttgaaga tatagttttg acattttcca ttacaaatac
     7321 atttggcttt aatttatcaa tagcatcaac atatagctta actaattcat tatttccatt
     7381 tataattttt cttttttgtc tattagcatt agaaaaacct tgacatggcg gtcctcctat
     7441 aacaacatct atcttatcga cactgtttaa tatatcttga aaatctaatc ttttaatatc
     7501 acaataacgc ttaacactcg gatgattttc aaggtatgtt tttgctgcgt tatcattttt
     7561 ttctacaaaa gccaccatat taaatttttt agtcatttca aatcctaagc tcaaaccacc
     7621 tgcacctgca aaaagatcta taacattata cattctgaca tacctcacat taacttttat
     7681 tgcagcatat catatttttt ttcacatgtc aatttttgaa taatcatttc aaatttctta
     7741 tacttgtaat agcttttaat aaattctaat atttttactt acacattatt tttcttattt
     7801 atgtcttctg gataatctat tcaaataaat aacataatat attttttatt tatttatcaa
     7861 tcttttttta tattatatac catatattat tttttagtaa tataattata atatagaata
     7921 aaaactattc taataaacaa tagtaactac taaaggagat ttaaatgtta actacaaata
     7981 tccattatat tcttgataat gatatatgtg aaatttattt taataaacaa aggctaacaa
     8041 attctaagta ttatcaagat aatattaatg tattaaatta tattataaat gaaaaaaata
     8101 ataacttaat tatcaattat aatgacaaat acatatatgc tatttatttg ttgaatatag
     8161 ctataaactc atacttaaat aatacattaa acccaaataa tcacattctt acaaaactcg
     8221 ataaaggtat gcccctgctc tacaagggtc aaatagttat atttaaaaat ataaataata
     8281 cacacataac tttaggacat aaaaataaaa cggatacaac acttatacct attgactcgg
     8341 cttatatgct tataacctat aatggtcatt tagaagtcaa ttctatgggc aaaactccag
     8401 catctaagac ttttcaaaca aagaatgttc tatcatcttt aggtttttca gacttaaaaa
     8461 atatgactgg agtaataaat gattctacac tgattatatt gccttgtaaa gatgatatat
     8521 ctgacttagt tagtaatatt aaaataaaag atattaataa tacttataag tttactgaac
     8581 tatttccatg ttcatatatt tcatcaactg gtgccgaaac tgattatcct ggaaatcacg
     8641 ctaagcaaat acctttactt aaatttacaa ctaatatttc tagtgcattt gaaattatta
     8701 aatctgataa gtctataaaa aatgtattta taataggtga ttatccaatt tataagcata
     8761 taaatgattt tgaaagaatt ttaaatagaa aaaggataga aagtgtaaat attgtaacct
     8821 caaattcaaa tataagcaat atattagatt taccaaatat agataatcta aatatatact
     8881 cttggtctaa agatgttctg ttaacctata gccaagattt tgaaaatacc tctacttttc
     8941 agaaattatg gctagataaa cttataaata aaaatatatg tactacttct gttgattcta
     9001 atatctctga cttgatacat caggctagaa aatcacttta ttacatatct aagtatgatt
     9061 ttgatatttc cataaaaaac tcacttatga tgtgtagtta ctctcttctt aaaatcttag
     9121 aaaatacacc ttttaaccta gattttttag aagaaactat aaagctttta aatttaaata
     9181 tagcaactcc ttcagcgaag ctagaaaata taaaatattt aatttcaagt actagcccag
     9241 atttagaatt aagtgcatta tttgatgatg ttatagtcaa atttgaaaga attataaatg
     9301 aattatctga taataatacc aaattcaata cactaaataa attagtatct tcatataaat
     9361 acaaaacatt tacaccaaat acacctgtta
//
LOCUS       DAEPHU010000113         9094 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 01A10CD0081
            SAMN05941466-rid12468953.denovo.113, whole genome shotgun sequence.
ACCESSION   DAEPHU010000113 DAEPHU010000000
VERSION     DAEPHU010000113.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941466
            Sequence Read Archive: SRR6291087
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 9094)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9094)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068158.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 22:43:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,892
            CDSs (total)                      :: 3,805
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 87
            rRNAs                             :: 8, 1, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 55
            CDSs (without protein)            :: 55
            Pseudo Genes (ambiguous residues) :: 0 of 55
            Pseudo Genes (frameshifted)       :: 21 of 55
            Pseudo Genes (incomplete)         :: 28 of 55
            Pseudo Genes (internal stop)      :: 16 of 55
            Pseudo Genes (multiple problems)  :: 8 of 55
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9094
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941466-rid12468953.denovo.113"
                     /strain="01A10CD0081"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            58..1146
                     /locus_tag="KR231_003474"
     CDS             58..1146
                     /locus_tag="KR231_003474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine protease StiP family protein"
                     /protein_id="HBH0005803.1"
                     /translation="MRDFSTYSKDDVIFLLKDISNLIEEEGNKERELKIQNGRHYSEM
                     IPIEYEVSEDYLNLYHEKLRENKDKLAFSIGVMCEKIIKKNGNDVVLVSLARAGTPIG
                     ILAKRYIRSKYNVSLPHYTISIIRDKGIDMNAIEYIVKNHPSSKIQFLDGWTGKGTIS
                     KELEKACDELNVKFKKYFDSTLAVLADPAGYSGLYGIREDFLIPSACLNSTVSGLVSR
                     TVLREDLISKNDFHGAKFYRHLKDKDESMNYIETIEECFKNQFKNISDEVENWESDII
                     TRDGYFDVLNIKEKYNITDINFIKPGVGETTRVLLRRVPYKILVKDLNDKSLDHIFIL
                     AKEKNVEVEQMDLKAYKCCGIIKNMKDI"
     gene            1174..1965
                     /locus_tag="KR231_003475"
     CDS             1174..1965
                     /locus_tag="KR231_003475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD hydrolase family protein"
                     /protein_id="HBH0005804.1"
                     /translation="MIVFSDLDRSIIYSNKFLNADSKYANIEIYREKEISYISLDTIN
                     LIKQIQYYGMFIPTTTRTVEQFKRIEFNKYGIYFPWSITSNGGVILKDNEILKSWSEK
                     IDKLKSDYEPIESMIHKFKDYLNVDGITNFKVAEDTFFYIVVDLSRFNLDSIKEYTNI
                     LESKNWKFYVSGRKIYFIPKEISKENAIKYLTKELGIEYFYAVGDSIMDYGMLNISNK
                     SYVLKHGDINKNEIENSFISSSFNGMSGTEEILSNILDENCLLNI"
     gene            complement(2080..2634)
                     /locus_tag="KR231_003476"
     CDS             complement(2080..2634)
                     /locus_tag="KR231_003476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupin domain-containing protein"
                     /protein_id="HBH0005805.1"
                     /translation="MNIDVGSKIRSLRKSKNISISTLAKNSDLSTGLISQIERNMVVP
                     SIVAMWKISKALDINIGYFFEEIGREDSDIVVKKNNRKKIVTNDSTKFYELLVPNLSG
                     KKIEFILVTLDGHTHKNSEFVTHEGEECGYIIKGKMKITLGNKEYLLEEGDSFYFNST
                     IPHVYENYDDEVCISVWAMTPPSF"
     gene            2830..4032
                     /locus_tag="KR231_003477"
     CDS             2830..4032
                     /locus_tag="KR231_003477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF819 domain-containing protein"
                     /protein_id="HBH0005806.1"
                     /translation="MKSFVSPDNIWVLWAVVTGWAAFSIYLEQKYNWASKVSGAIIAL
                     VGAMLLSNLNIIPVESVVYDQVWGYVVPLAIALLLYQCNIKKIWKESGRLLIIFLVGS
                     VGTVLGAMIGFLALKNVVPDLNIVAAMMTGSYIGGNVNFAAMSGAFDAPGELVSATVV
                     ADNLLMALYFFVLIAIPSIGFFRKHFKHPHVDEMESIGITEGETVAANYWGRKEISLK
                     DIAIAIGSAFIIVAVSVELSTWFKAIIPLSNPFLAMLNTLFGNQYLIITTLTMLFATF
                     MPNFFGDIKGAQELGTFLIYIFFVVVGVPASITLIIQKSPLLLLYCGIMVLINMLVTF
                     IVAKIFKFSLEEAILASNANIGGPTTAAAMAISKGWSKLVGPILIVGTFGYIVGNYFG
                     LLVGNILI"
     gene            4089..5069
                     /locus_tag="KR231_003478"
     CDS             4089..5069
                     /locus_tag="KR231_003478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889546.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase"
                     /protein_id="HBH0005807.1"
                     /translation="MIFDGHSDTWADVTIRRLNGEKDVFRRIHLDNFKRANIEGAIFV
                     IWIDPPYDKEPEKRVKQIISSIKDEIEDMKDVVNIVKKYSDIDKGISENKINILIGLE
                     GLSHIGRNIDLLDYFYKEVGARHASLTWNEQNELATGCLGDENRGLTEIGKKAVNKME
                     KLGMIVDVSHLNEKSFWDLMSVASKPVIASHSNARSLCDAKRNLTDNQLKEISNTGGL
                     VGINSFRGFTNSNPKKQDLIHLVDHIDYMVNLIGIEHVSFGFDFSDYLGKETIGSFTG
                     NASVPSVDGLESTHTAQNIVVELENRGYKKKDIELISSGNFYRLFKDILK"
     gene            5317..6270
                     /locus_tag="KR231_003479"
     CDS             5317..6270
                     /locus_tag="KR231_003479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron chelate uptake ABC transporter family
                     permease subunit"
                     /protein_id="HBH0005808.1"
                     /translation="MKKRYLVIGIIILSYFSLFIGAEDINIMHIFAKNQHKLMIFIMS
                     RIPRLISILIAGVGMSIAGLIMQQISKNKFVSPTTGATIDAAQFGIVICMLLVPTASI
                     FTKTIIAFVFSLVGTFTFMKIIGKLQFKNIIFVPLVGIMFGNIIGSMTDFIAYKYDLS
                     QNVSSWMQGDFSMILKGNYEILYITIPLIILAYIYANKFTVVGMGMDFATNLGLSYKR
                     IVNIGLIIVALVTVCVVVTAGNIPFIGLIVPNIVSLYMGDNIRASIWYTGLLGAIFVL
                     ICDIFGRIIIYPYEISIGLTVGVIGSILFLYLILRRNVNEA"
     gene            6260..7216
                     /locus_tag="KR231_003480"
     CDS             6260..7216
                     /locus_tag="KR231_003480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron chelate uptake ABC transporter family
                     permease subunit"
                     /protein_id="HBH0005809.1"
                     /translation="MKLSLNQKIYFVSILLFISIALFIIYGIDMNHLEYALSQRIPKI
                     FAMVLGGGCIAFTTVVFQTITNNQILTPSVLGLDSLYVMIQTIIVFIFGSSSSLIINE
                     NYNFIINVAMMIGASLLLYKTLFEKNKNNIFFLILVGMIFGTLFKSATTFIQVMIDPN
                     EFLALQTSIMASLNNINTNVLLIAFIIIIAIIPFIYDEIKYLDVLSLGKEQAINLGVD
                     FDKAVKKMIILIAILVSISTALIGPMTFLGLLLANITREIFKTYKHTYLISGSMLIGM
                     ITLIIGQFFIQHVFKFDTTLSVVINFIGGIYFIQLLLKGANR"
     gene            7213..7968
                     /locus_tag="KR231_003481"
     CDS             7213..7968
                     /locus_tag="KR231_003481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003234487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBH0005810.1"
                     /translation="MIEIKNIFKRYKNKNVVDDVSFSIEKGKITSFIGPNGAGKSTVL
                     SIVTRLIGGDGGEVIIEGKSLTNYSNKELAKKIAILKQSNNITLKLTIRELVGFGRFP
                     YSEGNLTKEDENYIDEAIEYMKLTDIQHKYLDELSGGQRQRAYIAMVIAQDTEYILLD
                     EPLNNLDMNHSVQMMKVLRSLCDELDKTIVLVMHDINFASCYSDNIVALKNGKVKKVG
                     RTDEIVNEKVLEDIYEMNFNIKNINGNRICIYF"
     gene            8060..9025
                     /locus_tag="KR231_003482"
     CDS             8060..9025
                     /locus_tag="KR231_003482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="siderophore ABC transporter substrate-binding
                     protein"
                     /protein_id="HBH0005811.1"
                     /translation="MNKKAAIVAAVAIIGLVTVFALGGSKKNESKTSENSNNTMKITH
                     NLGETDVKLNPKKVVVFDYSALDTMDALGVAENLVGLPKASLPASLEKYKDDKYADLG
                     GLKEPDLEGIKSANPDLIIINGRQEDFYEQLSKIAPTISTSKDDKKYLESVKNNIDKI
                     AKIFGVEEKANQEFSKIEKKIETLNKKVTDKNLNALTIMVNEGNLSVFGEESRFSILY
                     NSFGFENKDKNIKESSHGQNITFEYIAKQNPEVMFVIDRGIATGSDVKESSTAKSVLN
                     NDIIKSMDAYKNDNIIYLDSPTWYVNDGGLTSLNKMIDDASKAVN"
BASE COUNT         3570 a          922 c         1531 g         3071 t
ORIGIN      
        1 ctaaagtgtt ttaacaggat aaaatatatc acgattttaa gataggagtt gagtcatatg
       61 agagatttta gcacgtattc taaagatgat gttatttttt tattaaaaga tatatcaaat
      121 ttaattgaag aagaaggaaa taaagaaaga gaattaaaaa tacaaaatgg tagacattat
      181 tcagaaatga taccaataga gtatgaagtt agtgaagatt atctgaattt atatcatgag
      241 aaactaagag aaaataaaga taaacttgca ttttctatag gagttatgtg tgaaaaaata
      301 attaaaaaaa atggaaatga tgtagtacta gtttcacttg ctagagcagg aacacctatt
      361 ggtattttgg caaaaagata tataagaagc aagtataatg taagtttacc tcactataca
      421 atctctataa taagagataa gggaatagat atgaatgcaa ttgaatatat agtaaagaat
      481 catccgagct caaaaattca atttttagat ggatggactg gtaaaggaac tatatcaaaa
      541 gaacttgaaa aagcatgtga tgaacttaat gttaaattta aaaaatattt tgactcaaca
      601 cttgctgtat tagctgaccc tgctggatat tcaggacttt atggaattag agaagatttc
      661 ttaataccaa gtgcatgttt aaattcaaca gtttctggtt tagtaagtag aactgtacta
      721 agagaggatt taattagtaa aaatgacttt catggagcta agttttatag acatttaaaa
      781 gataaagatg aatctatgaa ctatatcgaa actatagaag aatgttttaa aaatcaattt
      841 aagaatatat ctgatgaagt tgaaaactgg gaaagtgaca ttataacaag agatggatac
      901 tttgatgttt taaatataaa agaaaagtat aacataacag atattaactt tatcaaacca
      961 ggtgtagggg aaacgactag ggttttactt agaagagttc cgtataagat tcttgttaaa
     1021 gacttaaatg ataaatcttt agaccatata ttcatattag ctaaggagaa aaatgttgaa
     1081 gttgaacaaa tggatttaaa agcctataaa tgttgtggaa taataaaaaa tatgaaagat
     1141 atttaggaaa tatattagac aggagaatat tgaatgattg ttttttcaga tttagacagg
     1201 agtatcattt actccaataa atttttaaat gctgatagta aatatgctaa tatagaaatt
     1261 tatagggaaa aagaaatatc ttatatatct ttagatacta taaatttaat aaagcaaata
     1321 caatattatg gtatgtttat acctacaact actagaacag tggagcaatt taagcgtata
     1381 gaatttaata aatatgggat ttattttcct tggagtataa cttcaaatgg aggagttata
     1441 cttaaagata atgaaatatt gaaatcatgg agtgaaaaaa tagataaact aaaatctgat
     1501 tatgagccca ttgaaagtat gattcataaa tttaaagact atttgaatgt agatggaata
     1561 actaatttta aagttgcaga agatacattt ttttatatag ttgttgattt atcaagattt
     1621 aatttggatt caatcaaaga atatacaaat atattggaat caaaaaattg gaagttttat
     1681 gtgagtggca gaaaaatata ttttatacca aaagaaattt caaaagaaaa tgctataaaa
     1741 tacttgacta aagaattagg aatagaatat ttttatgcag ttggagattc tattatggac
     1801 tatggtatgc ttaatatctc aaataaatcc tatgtattga agcatggtga tataaataaa
     1861 aatgaaatag aaaattcatt tatatcaagt tctttcaatg gaatgagtgg aactgaagag
     1921 atactatcta acattttaga cgagaactgc ctacttaata tataatgact gatatataaa
     1981 taataaacta gaaaaatctg aaataaatta tagtaaagtt tatcatacta atttatttca
     2041 gatttttatc aatttatatt taagtaagaa ctcaatatgt taaaatgaag gtggagtcat
     2101 tgcccagact gagatacata cctcatcatc ataattttca tacacatgtg gtatagtact
     2161 gttaaaataa aaactatctc cttcctccaa tagatattcc ttatttccaa gtgttatctt
     2221 cattttacct tttattatat agccacattc ttctccttcg tgtgtcacaa attcactgtt
     2281 tttgtgtgta tgaccatcta gtgtaacaag tataaattct atttttttcc cagataaatt
     2341 aggaacaaga agttcgtaaa attttgtaga atcattagtt actatttttt ttcgattatt
     2401 tttctttact actatatcag agtcttctct tccaatctct tcaaaaaaat aacctatatt
     2461 tatatcaaga gcttttgata ttttccacat tgctacaata gatggaacaa ccatattacg
     2521 ctcaatttga cttattaagc ctgtacttaa atctgaattt tttgctaaag tagagatact
     2581 tatattttta gattttctaa gagatctaat tttgcttcca acatctatat tcattagata
     2641 caaaccccct cagacatgat tataacatat aatttataaa gattaataaa ataaaaaaaa
     2701 agttttacaa tacaagtatt ttttatgcta tattgaattt tctgaaaaga tgcattataa
     2761 tagtattaat attcaatata ttgaatattg ataacgatat tttaatttaa tgaaatggag
     2821 gtaattaaga tgaagagttt tgtaagtcct gataatattt gggtattatg ggcagttgta
     2881 actggatggg cagcatttag tatttatttg gaacaaaagt acaattgggc atcaaaagtg
     2941 tcgggagcaa taatagctct tgtaggagca atgttattat caaatctaaa tattatacca
     3001 gtagagtctg ttgtatatga ccaagtatgg ggatatgttg ttcctttagc catagcttta
     3061 ttgttatatc aatgtaacat taaaaagata tggaaagaaa gtggaagatt gctcattata
     3121 tttcttgtag gttctgtagg aactgtactt ggagctatga ttggattttt agcattaaaa
     3181 aatgtagtac cagatttaaa tattgttgca gctatgatga caggttctta tataggtgga
     3241 aatgtaaact ttgctgctat gtcaggggcg tttgatgcgc caggagaatt agtatcagca
     3301 acagttgtag cagataatct tttaatggca ttatatttct ttgtcttaat agctatacca
     3361 tcaattggat tttttagaaa acattttaaa catccacatg tagatgaaat ggaaagtata
     3421 ggtataactg aaggagaaac agtagcagca aattattggg gaagaaaaga aatatcttta
     3481 aaagatatag caatagccat tggtagcgct tttataattg tcgcagtatc tgtagaacta
     3541 tcaacttggt ttaaagctat aataccatta tcaaatcctt ttttagcaat gttaaatact
     3601 ttatttggaa atcaatatct aataataact actttgacta tgttgtttgc cacatttatg
     3661 cctaatttct ttggtgatat aaaaggagca caggaattgg gtacattttt aatatatata
     3721 ttctttgttg tagtaggtgt tcctgcttca ataacattaa taattcaaaa atcaccatta
     3781 ctacttttat actgcggaat aatggtacta ataaacatgc tagttacatt tatagttgca
     3841 aaaatattta agtttagttt agaagaagct attcttgcat ctaatgcaaa tattggtggt
     3901 cctacaacag cagcagctat ggcaatatca aaaggatggt ctaagctagt agggccaata
     3961 cttatagttg gaacatttgg atacatagtc ggtaattatt ttggtctttt agtaggaaat
     4021 attttgatat aattttacgt gaaaaaaagt tgttttttag aaagattttt atttaattgg
     4081 aggttgttat gattttcgat ggacattcag atacttgggc agatgtaaca ataagaaggc
     4141 ttaacgggga aaaagatgta tttagaagaa tccatcttga taattttaaa agagcaaata
     4201 tagaaggagc tatttttgta atatggatag acccaccata tgataaagag cctgaaaaaa
     4261 gagttaaaca aattataagc tctataaaag atgaaattga agatatgaaa gatgttgtaa
     4321 acatagtaaa aaaatattca gatatagata aaggtataag tgaaaacaaa ataaatattt
     4381 taattggtct tgaaggatta agccatattg gaagaaatat agatttacta gattattttt
     4441 ataaagaagt tggtgcaaga catgcatcat taacttggaa tgaacagaat gaacttgcta
     4501 caggatgttt aggggatgaa aatcgtggtt taactgaaat aggtaaaaaa gcagtcaata
     4561 aaatggaaaa attgggcatg atagtagatg tgtcacattt aaatgaaaaa tcattttggg
     4621 atttaatgtc tgttgcaagt aagccagtta tagcttctca ttctaatgct aggagtttat
     4681 gtgatgctaa aagaaatctt acagataatc aattaaaaga aatttcaaat acaggtggat
     4741 tagttggaat aaatagtttt agaggattta ctaatagtaa tcctaagaag caagatttaa
     4801 tacatttggt tgaccatata gactatatgg taaatcttat aggtatagaa catgtatctt
     4861 ttggttttga ttttagtgat tacttaggga aagagactat aggttctttt actggaaatg
     4921 ctagtgtgcc aagtgtagat ggtcttgaaa gcacacatac agcacagaac atagtagtag
     4981 agcttgaaaa tagaggttat aaaaagaaag atatagagtt aatctctagt ggtaattttt
     5041 ataggctctt taaagatata ctaaaataat ataataaaga acttaaattt ataaaatagt
     5101 atatttatac aaataatatc tacatattta aattggcgtt cataatttat taaattaaat
     5161 tttaatgtta ctagaagttt caattctagt aacatttttt atgttaaaaa cagatataga
     5221 tatatattga caatgataat tattattgat aaactataaa agtgaaaatg ataataattt
     5281 tcattttaat taataaaaga tttttaagga gggagaatga agaaaaggta tttagtcata
     5341 ggaataataa ttttgtctta tttttcttta tttataggag ctgaagatat aaatataatg
     5401 catatatttg ccaaaaatca gcataaactt atgatattta tcatgagtag aataccaaga
     5461 ttaataagta tattgattgc tggtgtagga atgagcatag caggtcttat aatgcaacag
     5521 ataagtaaga ataaatttgt atcacctaca acaggtgcta caatagatgc agcacaattt
     5581 gggatagtaa tatgtatgct tttagtacca actgcctcta tttttacaaa gacaataata
     5641 gcatttgtat tttctcttgt agggactttt acgtttatga aaataatagg gaagttacaa
     5701 tttaaaaata taatctttgt accattagta ggtataatgt ttggaaatat aataggttct
     5761 atgacggatt ttatcgcgta taaatacgat ttgagtcaaa atgttagttc ttggatgcaa
     5821 ggtgactttt ctatgatact taaaggaaat tatgagatat tatatatcac aatacccctt
     5881 ataatattag catatattta tgcaaataaa tttactgttg ttggtatggg tatggatttt
     5941 gcgacaaact taggtcttag ttacaaaaga attgtcaata taggtctgat aatagtagca
     6001 cttgttacag tatgtgtagt cgttacagct ggtaatatcc cttttatagg tctaatagtt
     6061 cccaatatcg tatccttgta tatgggtgat aatataagag caagcatatg gtatactggt
     6121 ttacttggag cgatatttgt acttatatgt gatatttttg gaagaattat tatttatcca
     6181 tatgaaatat ctatagggct tacagttgga gttataggaa gtatactatt cctttattta
     6241 atattaagga ggaatgtaaa tgaagcttag tctcaatcaa aaaatttact ttgtaagtat
     6301 attactattc atatcaatag cactttttat aatttatgga atagacatga atcatttaga
     6361 atatgcatta tcacaaagaa taccaaaaat atttgctatg gtattaggtg gaggatgtat
     6421 agcatttact actgtagtgt ttcaaacaat tacaaacaat caaatattaa caccaagtgt
     6481 actaggttta gattcattgt atgtaatgat tcaaactata atagtattca tatttggttc
     6541 aagcagtagt ctgattataa atgaaaatta taattttatt attaatgtag ctatgatgat
     6601 tggagcttca ttgttattat ataagacgtt atttgaaaaa aataaaaata atattttctt
     6661 tttaatccta gtaggaatga tatttggaac cttatttaaa agtgcaacaa catttattca
     6721 ggtaatgata gaccctaatg aatttttagc tttacaaact agtataatgg caagtttaaa
     6781 caatataaac actaatgtat tgttaatagc atttataata attattgcca taataccttt
     6841 tatatatgat gaaataaagt atttagatgt attgtcgtta ggtaaagaac aagcaattaa
     6901 tttaggtgta gattttgata aagcagttaa aaaaatgata atattaatag caattttagt
     6961 ctcaatatca acagcactta ttggacctat gacattttta ggacttttac ttgctaatat
     7021 aacaagagaa atttttaaaa catataagca tacatacttg atttcgggtt ctatgttgat
     7081 agggatgatt acattgataa taggtcaatt ttttatacaa catgtattta agtttgatac
     7141 aactttaagt gtagtaataa attttatagg aggaatttac tttattcaat tactattaaa
     7201 gggggcaaat agatgataga gataaaaaat atatttaaaa gatataagaa taaaaatgtt
     7261 gtagatgatg tctcttttag tatagaaaag ggaaagataa catcttttat aggaccaaat
     7321 ggagctggaa aaagtacagt actatcaata gttacaagac ttataggagg tgatggtgga
     7381 gaagtaataa tagaaggaaa aagcttgact aattatagca ataaagaatt agcaaaaaaa
     7441 atagctattc ttaaacaatc taacaatata actttaaagc ttacaataag agaattagtt
     7501 ggatttggaa gatttccata tagtgaaggt aatctaacta aagaggatga aaattatatt
     7561 gatgaagcaa tagaatatat gaagttgact gatatacaac ataagtattt agatgaattg
     7621 agtggaggtc aaagacaaag agcttatata gcaatggtaa tagctcaaga tacagagtac
     7681 atattacttg atgaaccact gaacaatttg gatatgaacc attccgtaca gatgatgaag
     7741 gtacttagaa gtctttgtga tgagttagat aagactatag tattagtaat gcatgatata
     7801 aattttgcat catgttattc agataatata gttgcattaa aaaatggaaa agttaaaaaa
     7861 gtaggtcgta cagatgagat agtaaatgaa aaagttttag aagatattta tgagatgaat
     7921 tttaacatta agaatataaa tggaaatcga atctgtattt atttttaaaa tattgtatat
     7981 gaaaataaac ttgctatatg attttttata aagtttttaa attaaaataa agattaatag
     8041 gagagaggaa aatattgata tgaataaaaa agcagcaata gtagcagcag tagctattat
     8101 aggattagtg acagtgtttg cattaggtgg aagtaaaaag aatgaatcaa aaacatcaga
     8161 aaattcaaat aatactatga agataactca taacttggga gaaacagatg taaaattaaa
     8221 tcctaaaaaa gtagtggtat ttgattattc ggctttagat acaatggatg cattaggtgt
     8281 agctgagaat ttagtaggac ttccaaaagc gagtttacca gcatccttag aaaaatataa
     8341 ggatgacaag tatgcagatt taggaggatt aaaagaacca gatttagagg gtataaagtc
     8401 ggcaaatcca gatttaatta taataaatgg aagacaagaa gatttttatg agcaattgtc
     8461 aaaaatagca ccaacaataa gtacaagtaa agatgataag aagtacttag aatctgttaa
     8521 aaataatata gacaaaatag caaaaatatt tggagtagaa gaaaaagcaa atcaagaatt
     8581 tagtaaaatt gaaaagaaaa tagaaacttt gaataaaaaa gtaacagata aaaatttaaa
     8641 tgctttaact ataatggtaa atgaaggtaa tttaagtgta tttggtgaag aatcaagatt
     8701 tagtatatta tacaatagtt ttggatttga aaataaagat aaaaatataa aagaatcaag
     8761 tcatggacaa aatattactt ttgaatatat agctaaacaa aatccagaag ttatgttcgt
     8821 tatagataga ggaatagcta ctggcagtga tgtaaaagaa agctcaactg caaaatctgt
     8881 tttgaacaat gatataataa aatctatgga tgcatataag aatgataata taatatattt
     8941 agattcacca acatggtatg taaatgatgg tggtctaaca tctttaaata aaatgataga
     9001 tgatgcttca aaagcggtaa attaataatc cgatataatc aaaatatatt ttttataaaa
     9061 tgattatcaa ataaactagg agtttttaag aact
//
LOCUS       DAEPHU010000114         8756 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 01A10CD0081
            SAMN05941466-rid12468953.denovo.115, whole genome shotgun sequence.
ACCESSION   DAEPHU010000114 DAEPHU010000000
VERSION     DAEPHU010000114.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941466
            Sequence Read Archive: SRR6291087
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 8756)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8756)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068158.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 22:43:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,892
            CDSs (total)                      :: 3,805
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 87
            rRNAs                             :: 8, 1, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 55
            CDSs (without protein)            :: 55
            Pseudo Genes (ambiguous residues) :: 0 of 55
            Pseudo Genes (frameshifted)       :: 21 of 55
            Pseudo Genes (incomplete)         :: 28 of 55
            Pseudo Genes (internal stop)      :: 16 of 55
            Pseudo Genes (multiple problems)  :: 8 of 55
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8756
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941466-rid12468953.denovo.115"
                     /strain="01A10CD0081"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            875..5008
                     /locus_tag="KR231_003483"
     CDS             875..5008
                     /locus_tag="KR231_003483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014466370.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF11 domain-containing protein"
                     /protein_id="HBH0005812.1"
                     /translation="MATVSGQIVFDRNRSATIDSGDSGIANIPVVLQDIATGVRLVVL
                     TDASGNYVFTNVPNGNYRIVEAFGTTGGVPTPGNFATAIVGPVPIAEMPPISPPIGST
                     NLDGTTPNTLLITVAGSDITNQNILNGPVIYTPIENILDSCVSVSNVNLITDADNGTF
                     GFFPPGTPSNTGPEIEPYPNVTPDFTYVVPDPTKFTPLDGEYTVQNIMTNAMSNVIGA
                     WWRIADHTTGNETGRMMVVNGFNPGAVFFKSTVQVTPNTNYLFSTWILNLFKVTGYPP
                     PQLGVRIFDQNNNILYQATLGAQIPVNTNAPEWKEVGTVINSQNNNQLTVEFFSEGES
                     AIGNDYAIDDVSLREIAVPTFTPIKTSNTETANVGDIITYTVTLDNTCDSPLTNVFFR
                     DLIPNGLEFIPGTVTVDGVSVPGVDPNTGFSLPDIGGGTGVEVTFDVVVESIPNPNPT
                     NNIANIDYSYTPVEGGIPNDFSVDSNPVPVEVISADIEVTKLSEPTIVNPGEELIYTI
                     KVVNNGPFPSENVVLTDDVPASIINPEYSLDGGVTFQPWTGSLNIGTLEVGETRVIII
                     RGIVNPSTVGIITNTAVVSSTTADPNLNNNTSTIETEVNLLADILVMKTAEPNSAVPG
                     TLLRYTIQVENLGPANAENVILNDDIPASIINPEYSLDGGASFQPWNGSLNIGTLNSG
                     ISLTVLIQGTVSLNSSEYIVNTATVSSTTPDPDLSNNISTIITPVNPQAGISIIKVAD
                     EDVAVPGEEFVYTIEIFNEGPSNATNVVLTDDIPDVILNPEYSLDGGATFQPWNGSLN
                     IGTVAPGQLIRIIIKGLVSSTATGDITNTAEVSADVPEPVTDSSTVTTPIVPSADIEV
                     IKTSNMDTAVPEETFSYTITVTNLGPSAAQSIVLTDDIPDVILNPEYSLDGGVTFQPW
                     NGNLSIGTLDAGEIRSIIIRGTVSQTAVGTIINTATISSPTPDPNPDNNTSTDETDIS
                     PLADISVIKGNEPVAIPGGRFIYGIEIANAGPSFAENVTLTDNIPASILNPEYSIDNG
                     VTFQPWNGSLNIGTLDAGEIRNIIIRGTVSQTAIGTIINTATVSSTTPDPNLNNNTST
                     SEAEVSSSADISVVKRSNQTVVVPGDVLDYTIEVRNAGPSTAQNVTLTDNIPASILSP
                     EYSIDNGVTFQPWNGSLSIGTLDAGEIRNIIIRGIVSQTAIGTIINTATVSSTTPDPN
                     PDNNTSTSEIDISSSADISVIKLANKTEACVGEQIDFVIVVSNAGPENAQNVTLIDNV
                     SDKLKKAVFSLDRGVSFQPWTGSLNIGTLPAGTLRVIILRGIIKSTCLDRLTNIAEVT
                     STTPDSNLNNNISRVQVEIKQFCCNDCGCKDCCCNCCCNDCGCKNCCCNCCKNDFWC"
     gene            5465..5812
                     /locus_tag="KR231_003484"
     CDS             5465..5812
                     /locus_tag="KR231_003484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupin domain-containing protein"
                     /protein_id="HBH0005813.1"
                     /translation="MHENKKNLLDGSLAQYNDTAVPKIPVFAGNDITSEVYYFKPNQV
                     LNAHRHPNGEQIFVFLKGEGKMKLGEHECDVKNGDTVFVPTGEWHEITNGSNEEMVAV
                     QITKINAGAEYRG"
     gene            complement(5962..7011)
                     /locus_tag="KR231_003485"
     CDS             complement(5962..7011)
                     /locus_tag="KR231_003485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HBH0005814.1"
                     /translation="MFKKIVAIASSIIVSTICLTGCDFNSNDKKDESSSSKNLDKVTI
                     AEVTHSVFYAPQYAAITKGFFEDEGIKIDLINTQGADKTMAALISGEANVGLMGPEAS
                     IYVYNQNKNDYAVNFAQLTKRDGSFLVARKKMPNFSYNDLKGTEILGGRKGGVPLMTF
                     EYVLKEKGLTIGENLKAGNVNVRTDVQFGVMAGAFAGGEGDFTTAFEPTATAMEKEGS
                     GYIVTSIGKDSGEIPFTAYSTTRSYMKNNKDLIQRFTNAVYKGQLWIQQASSKEVAKA
                     MQPFFEDISLEDLTTVVDRYKSIDAWSQNPVLKEEGLKKLMTVMKEAKELDKEAPYKD
                     IVNTEFANNAIKNIK"
     gene            7397..8131
                     /locus_tag="KR231_003486"
     CDS             7397..8131
                     /locus_tag="KR231_003486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HBH0005815.1"
                     /translation="MKQNKYDDDRFFNKYSKMERSTNGLAGAGEWHVLKKMLPDFKGK
                     RVLDLGCGFGWHCQYAVENGAISAVGVDISEKMLKEARNKTQLDNINYICMPIEDINF
                     PKDSFDVVISSLAFHYIQSFEDICKNISNCLSNKGNFVFSVEHPIFTAYGSQEWYCDK
                     DGNNLHWPVDRYFEEGVRRSNFLGEEVIKYHKTLTTYLNALMKTGFEILEIIEPQPEE
                     KLLDTIPDMKDELRRPMMLLVSAKKR"
     gene            complement(8274..8717)
                     /locus_tag="KR231_003487"
     CDS             complement(8274..8717)
                     /locus_tag="KR231_003487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009290358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolyl-tRNA synthetase associated
                     domain-containing protein"
                     /protein_id="HBH0005816.1"
                     /translation="MPYEAVNHPPVYTIEEMEELKTLHMEFVVKNLFLRDAKGKEHFL
                     VVLGKDKKADLKDIRQQIDSKPLSFASEERLQKYLKLTKGAVTPFGILNDKEAVVKVV
                     FDKDLLKMDKIGIHPNDNTATVFLKFEDMKKLIEENGNEIYYVEV"
BASE COUNT         3273 a         1211 c         1340 g         2932 t
ORIGIN      
        1 tggtcttact cttggtttat tatcttcaac tgtagcaaaa tagaatgttg agttttcttt
       61 taaaaaattc attatttttt catgattaaa tcctctttgt atcttatact aatataatga
      121 atataaataa aatattcatt atacttaata taaatcgata taaaaacaat tacaatatta
      181 tattgattat tcgaaattat atataaaatt cagaaaaaat tttagtttac ataacaaaaa
      241 taaagtcaac taaaattatt gattttagat taaagtaccg gattaagcat ttaagtagat
      301 tttaagcttg atttgattgg aaaggtacaa actatcaccg aaaaaaatta aacccattta
      361 aaaagcaata taaaagcttg ttatttttga gaaaaataga ccctctaaac tcaattagat
      421 taaaaataaa atacagaaaa ttatatctct aaatatctta aataattaag tttaaatttt
      481 acgatatttt gtttgattat ttataatata aaagcatact cttaatcttc aaaatttaaa
      541 aagagtaaaa aataacaaaa aaatcactga catttcactg acaaattgta attttgttat
      601 tataaataca ttgaaaatac ttgattattg aaaaatggca taaaataata cattttatgc
      661 catttactat tatttgatag tttttaactt atgacataag atatttttta acacatacaa
      721 taaaatataa aaaaattgat attgcaaata aaaaaaatac atattagatg ttatagaaaa
      781 aaagcgcact tataggctta aaatgtcaca taaaagagtt ttaaagaata atatattatg
      841 aacacaaatt ttgtaatcac aaaggagtga taatatggca acagtatcag gacaaatagt
      901 ttttgataga aatagaagtg ctaccattga ttctggagac tcaggaatag ccaatatacc
      961 agttgtatta caagatatag caactggagt tagacttgtg gttctcacag atgcatcagg
     1021 aaattatgtt tttactaatg ttccaaatgg taactataga attgtagaag cttttggaac
     1081 tacaggagga gtaccaacac cagggaattt tgcaacagcg atagtaggtc cagttccaat
     1141 tgcagaaatg ccacctatta gtcctcctat tggttcaaca aacttagatg gtacaacacc
     1201 taacacacta ttaataacag tagcaggttc agatataaca aatcaaaata tattaaatgg
     1261 gcctgtgatt tatacaccta tagagaatat attggattct tgcgtatctg tatctaatgt
     1321 aaaccttatt acagatgcag ataacggaac attcggtttt tttccaccag gtacaccaag
     1381 taatacagga cctgaaatag aaccttaccc aaatgtgacg ccagatttta cgtatgttgt
     1441 accagaccca actaagttta cacctttaga tggagaatat acagtacaaa atattatgac
     1501 aaatgcaatg agtaatgtta taggagcttg gtggcgtatt gctgaccata ctacaggaaa
     1561 tgaaacagga agaatgatgg tggtaaatgg ttttaatcct ggagctgtat tttttaaatc
     1621 aacagtacaa gttacaccta acactaatta tttatttagc acttggattt taaacctttt
     1681 taaggtaaca ggatatccac caccacagct aggtgtaaga atatttgacc aaaataataa
     1741 tatactatat caagcaacat taggagctca aattccagtt aatacaaacg caccagaatg
     1801 gaaagaagta ggtactgtga ttaattctca aaataataat caacttacag tagaattttt
     1861 tagtgaagga gaaagcgcca ttggaaatga ttatgctata gatgatgttt ctttaagaga
     1921 aatagctgtt ccaactttta ctccaataaa aacaagtaac acagaaactg ctaatgtagg
     1981 tgatataatc acatatacag ttacattaga taatacttgt gatagccctt taactaatgt
     2041 attttttagg gatttaattc caaatggttt agagtttata cctggaactg taacggttga
     2101 tggagtatct gtaccaggag tagaccctaa tacaggtttc tcacttccag atattggagg
     2161 aggaacaggg gttgaagtaa cttttgatgt tgtggttgaa agtattccta acccaaatcc
     2221 tactaataat atagctaata tagattactc ctatacacct gtagaaggcg gtataccaaa
     2281 tgatttttca gtagattcta atccagttcc tgttgaagta atatcagcag atattgaagt
     2341 tacaaaatta tctgaaccta ctatagtgaa tccaggagag gaattaatat acactataaa
     2401 agtagtaaat aatggaccat tcccatctga aaatgtggtt ttaacagatg atgtaccagc
     2461 ttctattata aatccagagt attcattaga tggaggagta acttttcaac catggactgg
     2521 aagtttaaat atagggacat tagaagtagg agagacaaga gttattataa ttaggggtat
     2581 tgtaaatcca tcaacagtag gaattataac aaatacagct gtagtatctt caactacagc
     2641 agacccaaac cttaataata atacatctac aatagagaca gaagtgaatt tattagcaga
     2701 tattttagta atgaaaacag cagaacctaa ttcagctgtt ccaggtactt tattgagata
     2761 tactattcaa gtagaaaact taggaccagc aaatgctgaa aatgtaatat taaatgatga
     2821 tattccagct tctattataa atccagaata ttcattggat ggaggagcaa gttttcaacc
     2881 atggaatgga agtcttaata taggaacttt aaactctgga atttcattaa cagttttaat
     2941 tcaaggaaca gttagtttaa attcttcaga atatatagta aatacagcaa cagtttcttc
     3001 aactacacct gacccagatt taagcaacaa tatatctacc attattacac cagttaaccc
     3061 acaagcaggt atttctatta taaaagtagc tgacgaggat gtagctgttc caggagaaga
     3121 atttgtatat acaattgaaa tttttaatga aggaccatct aatgctacga atgtagtttt
     3181 aacagatgat ataccagatg ttattttaaa tccagaatat tcattggatg gaggagcaac
     3241 tttccaacca tggaatggaa gtcttaatat aggtacagtt gcaccagggc aattaataag
     3301 aattatcata aagggattag taagttcaac tgctacagga gatattacta atacagcaga
     3361 agtaagtgca gatgtaccag aaccagttac ggattcatca acagtgacaa ctcctatagt
     3421 tccatcagca gatatagaag taataaaaac tagcaatatg gatacagcag ttccagaaga
     3481 aactttcagt tatactataa cagttacaaa tttaggacca tctgctgcac aaagtatcgt
     3541 tttgacagat gatataccag atgttatttt aaatccagag tattcattgg atggaggagt
     3601 aactttccaa ccatggaatg gaaatcttag tataggcact ttggatgctg gagaaataag
     3661 aagtattata ataagaggaa cagtgagcca gacagcagta ggtacaatta taaatacagc
     3721 aacaataagt tcacctacac ctgacccaaa tccagataat aatacttcaa cagatgaaac
     3781 agatataagt ccattagcag atatttctgt gataaaaggc aacgaaccag ttgctatacc
     3841 aggaggaaga tttatttatg gaattgaaat tgcaaatgca ggaccatctt ttgcagagaa
     3901 cgtaacttta acagataata taccagcttc tattttaaat ccagagtact caatagataa
     3961 tggagtgact ttccaaccat ggaatggaag ccttaatata ggtactttag atgctggaga
     4021 gataagaaat atcataataa ggggaacagt aagtcaaaca gcaataggta caattataaa
     4081 tacagcaaca gtaagttcaa ctacacctga cccaaatcta aataacaata cttcaacatc
     4141 agaagcagag gtaagttcat cagcagatat ttctgtagta aaacgaagca atcagactgt
     4201 tgttgtacca ggagatgtac tagactatac aattgaggtg agaaatgcag gaccgtctac
     4261 tgctcagaac gtaactttaa cagataatat accagcttct attttaagtc cagaatattc
     4321 aatagataat ggagtgactt ttcaaccatg gaatggaagt cttagtatag gcactttaga
     4381 tgctggagag ataagaaata tcataataag gggaatagta agtcaaacag caataggtac
     4441 aattataaat acagcaacag taagttcaac tacacctgac ccaaatccag ataataatac
     4501 ttcaacatca gaaatagata taagttcatc agcagatatt tctgtaataa aattagcaaa
     4561 taaaacagaa gcatgtgtag gagagcaaat agattttgta atagtagtat caaatgcagg
     4621 accagaaaat gctcaaaatg ttactttaat agacaatgtt tcagataagc ttaagaaagc
     4681 agtattttca cttgatagag gtgtaagttt ccaaccatgg actggaagtc ttaatatagg
     4741 tacactacca gctggaactt taagagtgat tatattaaga ggaattataa aatcaacatg
     4801 tcttgataga ttaacaaata ttgcagaagt tacttcaaca acaccagatt caaaccttaa
     4861 caataatata tcaagagtgc aagtagaaat aaaacaattt tgttgtaatg attgtggttg
     4921 taaagattgt tgctgtaatt gttgttgcaa tgattgtggt tgtaaaaatt gttgctgtaa
     4981 ttgttgtaaa aatgactttt ggtgttgatt ttataaaata attttgtata ccttaaatta
     5041 aactgaaata aaaaataaat tcacatatga gtaaaatatt ttataaatat taataaattt
     5101 tctatctttg atatggacca cattcgtaat actagttatt aaatgaagtg gtccttttta
     5161 attcattaaa attatttatt ctaattaaat tttaaatgta ttaaataatt ttaatttttt
     5221 ataaaaaata ttcatatgtt atttatatta aagtttagat atctaaaaat acttttagaa
     5281 tttattatat tatgttaatt ttttatatct tataaggatt gtatttttct aactataaaa
     5341 atagtattat acttatattt aaaaataaaa gaattttatt cctattgtgt aaagtgagaa
     5401 tactattttc ttatattggt ataataatag taaatctata atatagaaaa gaggtatttc
     5461 tagtatgcat gaaaataaaa aaaatctatt agacggaagc ttagctcaat ataatgatac
     5521 agcagttcca aaaataccag tatttgctgg taacgatata acttcagaag tttattattt
     5581 taaacctaat caagttctta atgctcatag acaccctaat ggtgaacaaa tatttgtgtt
     5641 cctaaaagga gaaggtaaaa tgaaacttgg tgagcatgaa tgtgatgtaa aaaacggaga
     5701 tactgtattt gtaccaacag gagagtggca tgaaattact aatggaagca atgaagaaat
     5761 ggtagccgtt caaattacaa aaattaatgc tggagcagaa tacagaggat agatatataa
     5821 gtacagttag tactttaata tctattttat tatataaact ttaatctcaa atataaaaag
     5881 agtcttttaa aaggctcttt ttatattttt gttaattttc attataaaaa caagaaaata
     5941 tctagctaaa actaatatat tttatttaat attttttata gcattgtttg caaactcagt
     6001 atttacgata tctttataag gtgcttcctt atctagttct ttagcttctt tcataacagt
     6061 catcaatttc ttcaaacctt cctcttttaa tacaggattt tgagaccatg catctattga
     6121 tttatatcta tctacaactg ttgttaaatc ttctaaagat atatcttcaa agaaaggttg
     6181 catagcctta gctacttctt tgctagatgc ttgttgaatc cataattgac ctttataaac
     6241 agcatttgta aatctttgaa ttaaatcttt attgtttttc atgtatgatc tcgtagtaga
     6301 gtatgctgta aaaggtattt ctccagaatc ttttcctata gatgtaacta tatatccact
     6361 accttctttt tccattgctg ttgctgtagg ttcaaatgct gttgtaaagt caccctctcc
     6421 acctgcaaaa gctccagcca ttacaccaaa ttgtacatca gttcttacat taacattgcc
     6481 tgcttttaga ttttctccaa tagtaagacc tttttctttt agaacatatt caaaagtcat
     6541 tagtggaact ccaccttttc taccacctaa tatttcggtt ccttttaaat cattgtaaga
     6601 gaaattaggc atttttttcc tagcaactag aaaactacca tctctttttg tcaattgagc
     6661 aaagttcact gcataatcgt ttttgttttg attatataca tatatagatg cttcaggacc
     6721 cattaaacct acgtttgctt cacctgaaat caaagctgcc atagttttat ctgcaccttg
     6781 ggtatttata aggtcaatct ttataccttc atcttcaaag aatcctttcg taatagcagc
     6841 atactgtgga gcataaaaaa cagagtgagt aacttctgct atagttactt tatccagatt
     6901 tttagacgaa gaagattcat cttttttgtc attagagtta aaatcacatc cagttagaca
     6961 tattgtactt acaatgatag agcttgctat tgcgactatt tttttaaaca taataaatac
     7021 ctcccataag acatacgaat agtatatagt attaaatatt tattgtagtt gttacaaaaa
     7081 tgtatctata cttataatat ttctacaaaa acttaataat aattttcagt tttatgttta
     7141 gttttttcag taatgtgtaa tattggataa attatattga ttatttataa actaagtaat
     7201 aaaattaaaa taatatcact tttttgtcta ttatatataa ggaaaaattt tttaataata
     7261 taaatcatat tcatttatat tattaaaaaa tttgtttata gaaactttta ttattttata
     7321 taaaagtgat aaaaacttat attttgtatt taatagagtg ttgctaagtg aatatattta
     7381 aaatggagga aactttatga aacaaaataa atatgatgat gatagatttt ttaataaata
     7441 cagtaaaatg gaacgttcta caaatggatt agcaggtgct ggagagtggc atgttttaaa
     7501 aaaaatgtta cctgatttca aaggaaaaag agttttagat ttaggatgtg gatttggatg
     7561 gcattgtcaa tatgcagttg agaatggagc aatttctgct gttggagttg atatttcaga
     7621 aaaaatgtta aaagaagcta gaaacaaaac gcaacttgat aatataaatt acatatgtat
     7681 gcctattgaa gatattaatt ttccaaaaga tagttttgat gtagttatta gttccttggc
     7741 atttcattat attcaatcat ttgaagatat atgtaagaat ataagtaatt gtctttcaaa
     7801 taaaggtaat tttgtatttt ctgttgaaca tcctatattt actgcatatg gaagtcaaga
     7861 gtggtactgt gataaagatg gaaataatct acactggcca gtagatagat attttgaaga
     7921 aggagtacgt aggtcaaatt ttctaggaga agaggttata aaatatcata aaacattaac
     7981 aacttattta aatgcgttaa tgaaaacagg atttgaaata ttagaaatta ttgaacctca
     8041 accagaagaa aaactgttag atacaattcc tgatatgaaa gatgagctac gtagacctat
     8101 gatgttactt gtatctgcaa aaaaaagata agtaaatata aataatcatt attgtagaaa
     8161 aaaagttgta gaaaataatt acactaatgg agatgattat accagtggta ttaattacac
     8221 cagtagtaag gaggcaaaag cattcgttgc ttttgccatt ttttaagttg caattatact
     8281 tctacgtagt atatttcgtt tccattttct tctataagct ttttcatatc ttcaaatttt
     8341 aaaaatacag tagcagtatt atcatttgga tgtataccta ttttatccat ttttaataaa
     8401 tccttatcaa atacaacttt tacaacagcc tctttatcat ttaatatacc aaaaggagtc
     8461 acagctcctt tagtaagttt caagtatttt tgaagtcttt cttctgatgc aaaactaaga
     8521 ggtttactat caatttgttg acgaatatct tttaaatctg cttttttgtc tttacctaat
     8581 acaactaaaa aatgttcttt tcctttagca tcacgaagaa ataggttttt tacaacaaat
     8641 tccatatgta atgtttttaa ttcttccatt tcttcaattg tataaactgg tggatgattt
     8701 acagcctcat aaggtatgct taactcatct aattttttat atacttcctg ttgttg
//
LOCUS       DAEPHU010000115         8686 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 01A10CD0081
            SAMN05941466-rid12468953.denovo.116, whole genome shotgun sequence.
ACCESSION   DAEPHU010000115 DAEPHU010000000
VERSION     DAEPHU010000115.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941466
            Sequence Read Archive: SRR6291087
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 8686)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8686)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068158.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 22:43:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,892
            CDSs (total)                      :: 3,805
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 87
            rRNAs                             :: 8, 1, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 55
            CDSs (without protein)            :: 55
            Pseudo Genes (ambiguous residues) :: 0 of 55
            Pseudo Genes (frameshifted)       :: 21 of 55
            Pseudo Genes (incomplete)         :: 28 of 55
            Pseudo Genes (internal stop)      :: 16 of 55
            Pseudo Genes (multiple problems)  :: 8 of 55
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8686
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941466-rid12468953.denovo.116"
                     /strain="01A10CD0081"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            complement(255..1055)
                     /locus_tag="KR231_003488"
     CDS             complement(255..1055)
                     /locus_tag="KR231_003488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PIG-L family deacetylase"
                     /protein_id="HBH0005817.1"
                     /translation="MTFKNKKFTINKYKILSIILVLCLILTAFSSYVNYSHKKFKDYV
                     VFYVQHQDDEVLWAGSAIVNAIKERGKNHVFVVLVSTGCGISVFDKYKKYENLTNIQK
                     SEYRNREFLASLNSLGVIRENIILLPETNTNGNTDFNYMEKIALTFEEKFKNVTHIAH
                     TYKLDDHLQHLKNGSVIQNLYNAGKIKDAKYFVKPKFADKITFNNKIVYKAHSTEDYE
                     KVKNACQQYKIVDELEYREGIGYKSDHKSFDKLLNNKDVPAILHTPNL"
     gene            complement(1369..2100)
                     /locus_tag="KR231_003489"
     CDS             complement(1369..2100)
                     /locus_tag="KR231_003489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0005818.1"
                     /translation="MNIFDILRDYLLVQVDKYNLNMDMISIVSKSLSSKEAIGNTKRK
                     DFPIIVGKEIMLEADFKGAKGQAFTSTPSTFEGSLKDILSLDLHDNSHDRSLFIASLN
                     AVMKYLGKTDRTIHCKNNEPEVCAKKFPEFIKMEFGNPKVAIIGYQPAIIDNIKDFFE
                     TRVLDLNPEFVDTIQYNVKIEDGIRDYEDVISWADLVICTGSTLCNNSIINFLSLNKP
                     VYYYGTTIAGASNILGLKRLCFCSK"
     gene            complement(2087..2782)
                     /locus_tag="KR231_003490"
     CDS             complement(2087..2782)
                     /locus_tag="KR231_003490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBH0005819.1"
                     /translation="MLKIKNLSLDLPNFKLQENSLNINNHEYFVLLGASGSGKTLFLE
                     TLAGRYPSAKGNVSYKENLISNLPPENRNIGFVYQNFELFPNMNVEDNIRFPLKLRKI
                     PIDEQILKANHLSKLMQIEDIKNRYPKNLSGGEKQRVAFARALIAEPDILLLDEPMSS
                     LDYITKKHISKILKDVYIKYKPTVIHVTHDISEAMFFAHKIGIMNNGKINHIFDLNEE
                     IKNKGESFFYEYI"
     gene            complement(2784..3575)
                     /locus_tag="KR231_003491"
     CDS             complement(2784..3575)
                     /locus_tag="KR231_003491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBH0005820.1"
                     /translation="MKNKFFTTLLTGFFAIVFLFIVSPLLMLIIKGISYVPICLKSVE
                     VQYAITLSIKTSLISTIVCLLLAIPVAYFLHITKLPFKKLIIQIINLPMSLPHLVSGI
                     ALLLLFGRMGIGDSIYKIFKLDFIFTKQGIVLAQIFVNLPLTIKILHTSLNESNEKMI
                     FVARTLGCNSWEAFRFIILPNLKTGIISATVMTWSRALGEFGAVAMIAGSTRMKTEII
                     PTSIYLNMSTGDIDIAIGIAVILIFLSLTCLMLFEIFFNREVDKN"
     gene            complement(3585..4397)
                     /gene="modA"
                     /locus_tag="KR231_003492"
     CDS             complement(3585..4397)
                     /gene="modA"
                     /locus_tag="KR231_003492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdate ABC transporter substrate-binding
                     protein"
                     /protein_id="HBH0005821.1"
                     /translation="MFKKLSVLALAMIISLSITACNSKENKANDESNTKVTTADDSKE
                     KETLFVYSGAGLKKPMDEIAKKFEKENNVKVEYSYAGSAQLIAQIETSHKGDVFIVGS
                     EPIYSKAFEKELVGEHKTVAHHTPAIVVPKGNPANIQKLEDLNKDGVKLILGDKESNA
                     IGKTTQKILEKNNLKSINDNVVSTAATVNEMIVQLTSSKADATIATKDSVFGNEDVEV
                     IEIAQDKNIDQLISAGIVNYSDKKDLANKFINYIESDEAKQIFKKYGFEPVK"
     gene            complement(5032..5232)
                     /locus_tag="KR231_003493"
     CDS             complement(5032..5232)
                     /locus_tag="KR231_003493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003723180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HBH0005822.1"
                     /translation="MNNGIVKWFNNEKGFGFISMESGDDVFAHFSAIQTSGFKSLEEG
                     QKVSFDIVKGARGPQAENITIL"
     gene            complement(5457..5633)
                     /locus_tag="KR231_003494"
     CDS             complement(5457..5633)
                     /locus_tag="KR231_003494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0005823.1"
                     /translation="MFRDKMDKCTHMLTAYIGSSYDYCDFIDTQLDDFILEYGEKVVE
                     SCLHQVMVLVSKYN"
     regulatory      complement(5687..5776)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01051"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="cyclic di-GMP riboswitch class I; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="cyclic di-GMP"
                     /db_xref="RFAM:RF01051"
     gene            complement(5956..6156)
                     /locus_tag="KR231_003495"
     CDS             complement(5956..6156)
                     /locus_tag="KR231_003495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454608.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBH0005824.1"
                     /translation="MPKFTCNLKKYRQLKELTQEQLAEKVGVRRETIMRLEAGKYNPS
                     LKLAIDISKIVDTPIDELFIFD"
     gene            complement(6158..6508)
                     /locus_tag="KR231_003496"
     CDS             complement(6158..6508)
                     /locus_tag="KR231_003496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3796 domain-containing protein"
                     /protein_id="HBH0005825.1"
                     /translation="MIQKKFFMGFCGFLGFLSLRYFSSGNVADLTYIGFFAFFSNFII
                     SKINGDKADERYVQDEKAAMAFTGQLAIIELFILWCITIVSRNIELMCVLLSITYAIT
                     LNVYAIKLYILEEK"
     gene            6670..6859
                     /locus_tag="KR231_003497"
                     /pseudo
     CDS             6670..6859
                     /locus_tag="KR231_003497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890498.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(7336..7506)
                     /locus_tag="KR231_003498"
     CDS             complement(7336..7506)
                     /locus_tag="KR231_003498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0005826.1"
                     /translation="MHVYQPKTSEYLLNTYAKSYLSSIVFLFDYITKNESGYAFFIID
                     FPFLSLDIFYKF"
     gene            complement(7895..8389)
                     /locus_tag="KR231_003499"
     CDS             complement(7895..8389)
                     /locus_tag="KR231_003499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin-type N-terminal cleavage/methylation
                     domain-containing protein"
                     /protein_id="HBH0005827.1"
                     /translation="MKNKKGFTLVELLVVIAIIGILAIVALPALFKNIEKAKIAKLEA
                     DISAIKSASLSYYADESKYTDGGMISWVKKDGKIIINGGFKDDPLADKIENLGMPYNG
                     SYLLMSSPGHEKYLELSILPEGEISKSGLDKLKSDYGSSIDIMNEQNKIDIVIKFLND
                     KSNT"
BASE COUNT         3162 a         1170 c         1013 g         3341 t
ORIGIN      
        1 aattattaag aatttataac aaatatttat tttaatgtag tttaatataa acaggtagtt
       61 taatgtaggt atgtataaag catttaataa ggcttatagg ttttaatgat gatatcttta
      121 tatattttaa gagatgatga aattagatat gggtaatagt tgtatgagaa aaagtagtat
      181 agcacaaaaa gtgctatatc acaaaatctc aaataatttc ctttttataa cttaaattaa
      241 agaataaata tttcttataa attaggtgta tgaagtatag caggaacatc tttattattt
      301 aataacttat caaatgattt atggtcagac ttatagccaa taccttctct atattctaat
      361 tcatcaacaa ttttgtattg ttgacaggca tttttaacct tttcatagtc ctcagtagaa
      421 tgagctttat aaactatctt attattaaaa gttattttat cagcaaattt aggttttaca
      481 aaatatttag catcttttat tttaccagca ttatataaat tttggataac agaaccattt
      541 tttaaatgtt gtaaatggtc atctaattta taagtatgtg ctatatgagt tacattttta
      601 aatttttctt caaatgtaag agcaattttt tccatgtaat tgaagtcagt attaccattt
      661 gtatttgttt ctggtaataa tattatattt tcccttatta caccaaggct attaagagaa
      721 gctaaaaatt ctctatttct atattctgat ttttgtatat ttgttaggtt ttcatatttt
      781 ttatatttat caaagacgga tataccacat ccagtagata ctaaaaccac aaatacatga
      841 ttttttcctc tttcttttat agcattaaca atagcactcc cagcccacaa cacttcatca
      901 tcttgatgct gaacatagaa gacaacataa tctttaaatt ttttatgact ataattcaca
      961 tagctactaa aagcggttaa aatcaaacat aaaactagaa taatagatag aattttatat
     1021 ttatttatag taaatttttt attcttaaat gtcatttaat catctcctga aaggttgtct
     1081 tagttatatt atcaaacaaa gtactaaaaa ttatttctta aatgctgaaa aatatagagt
     1141 agattaatgg aataaaattt ttttattagt ttaaaataaa gaaaacattt atgtataaga
     1201 ctaatcaaaa tattaatgat tgataggaat tgagatttaa agggattgta catttattcg
     1261 ggattcattt taatagaatt ttactttagt acttagaata aaagtaataa ctttttaaat
     1321 ttaaagagta cacatatata tttgtgtact ccttgatgat atgattgctt atttactaca
     1381 aaaacagagt ctttttaaac ctaaaatatt tgatgcacca gctatcgtag ttccataata
     1441 gtaaactggt ttgttaagtg atagaaaatt tataattgag ttattacata atgtacttcc
     1501 tgtgcaaatc actaaatcag cccaagatat tacatcttca taatctcgta taccatcttc
     1561 aatcttaaca ttatattgaa tagtatccac aaattcagga tttaaatcta atactcttgt
     1621 ttcgaaaaag tccttaatat tatcaattat ggctggttga tatcctataa ttgctacttt
     1681 tggattacca aattccattt ttataaactc agggaatttt tttgcacata cctctggctc
     1741 gttattttta caatgaatgg ttctatccgt cttgcctaag tatttcataa ctgcatttaa
     1801 tgatgctata aaaagacttc tatcatgaga attgtcatgt aaatctaatg ataatatgtc
     1861 ttttaaagaa ccttcaaatg tagatggagt agaagtaaat gcttgtcctt tagctccttt
     1921 aaagtcagct tcaagcatta tttctttacc aactataatt gggaaatctt tacgcttagt
     1981 atttccaatt gcttcttttg aagatagaga tttggacaca atacttatca tatccatatt
     2041 taaattatat ttatcgactt gtactaatag ataatctctc aaaatatcaa atatattcat
     2101 agaaaaaaga ttctccttta ttttttattt cttcatttaa atcaaaaata tgatttattt
     2161 ttccattgtt cattattcct atcttatgag caaaaaacat tgcttcagaa atatcatgag
     2221 taacatgaat cactgttggt ttgtatttta tgtagacatc cttcaaaatt ttgcttatat
     2281 gtttttttgt aatataatcc aatgaactca taggttcatc taaaagtaat atatcaggtt
     2341 cagctattaa ggcacgtgca aaagcaactc gttgcttttc gcctccactt aaatttttag
     2401 gatacctatt ttttatatct tctatctgca ttaatttaga caagtggtta gccttaagaa
     2461 tctgttcatc tataggtatt tttctcaatt taagtggaaa ccttatatta tcttcaacat
     2521 tcatatttgg aaataattca aaattttgat atacaaatcc tatatttcta ttttctggag
     2581 gtaagtttga tattaaattt tctttgtatg atacatttcc tttagcagat ggatatcttc
     2641 ctgctaatgt ttctagaaat agagttttac ctgacccact agctcctaat aaaacaaagt
     2701 attcatgatt attaatattt aaactatttt cttgtaattt aaaattaggt aaatcaagag
     2761 ataaattttt tatttttaac atattaattc ttatcaacct ctctattaaa aaatatctca
     2821 aaaagcatca agcatgtaag tgagagaaat atcaaaatta cagctattcc gatagcaatg
     2881 tctatatcac cagtagacat atttaaatat atagatgtag gaataatttc agttttcata
     2941 cgtgtagaac ctgctatcat agctactgca ccaaattcac caagtgctct tgaccaagtc
     3001 attacagttg cagatatgat tccagttttt agatttggaa gaattataaa tctaaatgct
     3061 tcccaactat tacatccaag ggtacgtgca acaaatatca tcttttcatt actttcattt
     3121 aatgaagtgt gaagtatttt aatagtaagt ggaagattta caaatatttg tgctaaaact
     3181 ataccttgct ttgtaaatat aaaatcaagc ttaaaaatct tataaatgga atctccaatc
     3241 cccattcttc caaacaaaag taaaagagca attcctgata ctaagtgtgg aagagacata
     3301 gggagattta ttatctgtat aatcagtttt ttaaatggta atttagtaat atgtaaaaaa
     3361 tatgctactg gaatagctaa taaaaggcat actatagtag atattaaaga tgttttaata
     3421 ctaagtgtta ttgcatactg tacttccact gattttaagc atataggaac ataacttatc
     3481 cctttaatga ttaacataag aagtggtgat acaataaaca aaaagactat agcaaaaaat
     3541 ccagtaagta gagtagtaaa aaatttattt ttcaagttta atcactactt aacaggttca
     3601 aaaccatatt ttttaaatat ctgtttagct tcgtctgact ctatataatt tataaattta
     3661 ttagctaaat cttttttatc actatagttt acgattcctg ctgatatgag ttggtctata
     3721 tttttatctt gggcaatttc tataacttct acatcttcat taccaaagac cgaatctttt
     3781 gtggctattg tagcatcagc tttacttgat gttaactgta caatcatttc atttacagtt
     3841 gcagctgtag agacaacatt atcatttata gattttaaat tatttttttc aagtattttt
     3901 tgtgtagtct tacctatagc attagactct ttgtctccca aaataagttt aactccatct
     3961 ttatttaagt cttccaattt ttgaatatta gctggatttc ctttaggtac aactattgca
     4021 ggtgtatgat gtgcaaccgt tttatgttca cctacaagtt ctttttcaaa ggcctttgaa
     4081 taaattggtt cagaaccaac aataaatacg tctcctttgt gacttgtctc aatttgagct
     4141 attagctgtg cagaacctgc atagctatat tcaactttga cattattttc tttctcaaat
     4201 ttttttgcta tttcatccat tggtttcttt aaacctgccc ctgaatagac aaaaagagtc
     4261 tctttttctt ttgaatcatc agctgttgtc actttagtat tagattcatc attagctttg
     4321 ttttctttag aattacatgc agtaatactt aatgaaataa tcatagctaa agctagtact
     4381 gaaagttttt taaacataag atattccccc ttattaaatt agtgtaaatt cttttttagt
     4441 atatcatact aagaaaacga tgtctaagtt tttgttatgt tttataatgt tttgttatgt
     4501 tttgttatgt atagttaaga aaaaatctat tcataatgtc atttccatag gtagttattt
     4561 tatttttaat ttttattaat actttaaagt attttaaatt taaaaactta aatcaaatta
     4621 acttattgta gattttttac tttttaacta attttatatt tattatattt cagtgaaaaa
     4681 atagaacatt gaaacatata gatatgtttt aattgctttt tattaacaaa ttactaaaag
     4741 tattatatca gaattgaata caaaagaaag agtatgtatt tatgagatag ttgaaaattt
     4801 tgatgtgcca caactaaaat tattatatta ctatatattc taattaaaag agtacttgta
     4861 ggtttaagta catactttat aaatatattt ttgtcagatt tattttataa aaagtattta
     4921 gactaagtat tatttttaag tatttttttg ttgaagttat tttttccttt tttacaaaat
     4981 gcgtaaataa aaaaaagact cttaaaagag tctttccgaa aaatctatat attataatat
     5041 agttatattt tctgcttgag gacctctagc gcctttaact atatcaaagc ttactttttg
     5101 accttcttct aatgatttaa atcctgaagt ttgtatagct gagaaatgag caaatacgtc
     5161 atctccactt tccattgata taaatccaaa tcctttttca ttattaaacc attttactat
     5221 tccattattc attaaaaata ctcctattaa cctatatcaa gatatacttg atttacttgt
     5281 gtattaccac aaatactatt gtatcataga ttaacataaa tgtctattta attataattt
     5341 ttagttaaca tttttattta ttcttaatat gaaaataaat ttaaacattt tatattacca
     5401 atatattaat gtaaatgtag ataaaactaa aaagggtttt ctagaaaaaa atctgtctaa
     5461 ttatacttac ttaccaatac catcacttga tgcaagcaag attccacaac tttttctccg
     5521 tactctaata taaaatcatc taactgtgta tctataaaat cacaataatc atatgaacta
     5581 ccaatataag cagttaacat atgtgtacat ttatccattt tatctctaaa cataatgtat
     5641 ttatccccct aaaaaacttt catgaaaaac aaaaagaaaa tatctttttg gcaactggct
     5701 gacataactt attttataag cgttagtccc tatagctttg cgtcactaaa tttctctagt
     5761 tttgccgatt tagttttatt ctacagatta ataatacaat agaattagtt attattcaac
     5821 atatctagct gaaaaattaa taaatttata tatgaacgtt aaattatctg aaaaaataaa
     5881 aagcccctct gtcaggagtg acttaaaaat tgaatttaag tttgtattta aaacacattt
     5941 ttaataatgc aaaaactaat caaaaataaa caattcatca ataggtgtat ctactatttt
     6001 tgatatatct attgctaatt tcaaagaagg attatacttt cctgcttcta aacgcataat
     6061 ggtttctctt ctaactccta ctttttctgc taattgttct tgagttaatt cttttaattg
     6121 tctatatttt tttaggttac aagtgaattt aggcatatta tttttcctct aaaatataaa
     6181 gttttatagc ataaacattt aaagtgattg catatgtaat tgatagtaaa acacacatta
     6241 attctatatt cctagacact atagtaatac accataaaat gaataattct ataatagcaa
     6301 gctgtcctgt aaatgccata gctgcttttt catcttgtac atacctttca tctgctttat
     6361 caccatttat ttttgatata ataaagtttg agaaaaaagc aaaaaatcca atatatgtaa
     6421 ggtcagcaac attgccagat gaaaaatatc taagacttaa aaatccaagg aaaccacaaa
     6481 aacccataaa aaattttttc tgaatcattt tttatcctcc ttagtaattt taaaagagat
     6541 atatttatat ctttatgata caaatatatc tcttttatat tcttttgtca atagaaaatc
     6601 agtattatac aatatttgta ctgcaccata attgttagag caaaaatcta ctgcttgaga
     6661 tgtttatgta tgactaaata tgattttaat ttcaaattaa aagtagctaa attttatttg
     6721 aatagagaag gaagagatat tttaatagta aaacaatatg gagtttataa ccattctcaa
     6781 gttgaaagat gggttaatat attaggagag tgtgcactaa aaataaaaaa aattttctat
     6841 actatatggt tcaagttaga tgttataaac tatatgatga taactaaata tagtgtacaa
     6901 taaatcgcta agtattttgg aataaacaat agcacagtta tagcaacatg aaaataaaaa
     6961 tttttacata gtggtgttga tgccttttct aaaatgaaag gaagaccata atgaataaaa
     7021 acaaaaacac taaagaaaaa ataaattaac aagagaacaa gaattagaat atgaaaataa
     7081 atttttaaaa gatgagcttg agtttttaaa aaagatgtgt gcctcaggga agccacatta
     7141 aaaaacagtg gtatcattat taatcaaaag aaagttagat gtattatcaa aaaattagaa
     7201 cttaaatgca tagcattttt tcataaatca cataaatata actcctataa atgtataatt
     7261 ggaaaagtaa aaaataataa aacaaataga agatttaaaa tatcaatagc atatcagaaa
     7321 ataacaaatg atatgctaga atttataaaa tatatctaat gataaaaatg gaaaatcaat
     7381 tataaaaaag gcatatcccg attcattttt tgttatatag tcaaataaga atactataga
     7441 tgaaagatac gattttgcat atgtattaag taagtattct gatgtttttg gttgatacac
     7501 atgcaataaa gaagttgtgt ttgcagataa attagcaaaa ctatagtata agttgcaaca
     7561 ataaagaaaa tgaaaattat catactaaag cataaggcat gttacaattt tattagatag
     7621 gacattaaca tacattaaag tactttttat tataaagagt acttattttt ttgaaattca
     7681 ttaatgtata aactatcaag aatattactc aacataattt aaaaacaact tgaataggta
     7741 tttttaaatt atgtgatata ataaaaaata gaagtgtatg ccaatacact tctgtaatta
     7801 taactaagca ttctattctt gaggagtgct tttttcattt ctccaaacaa gattgtttat
     7861 ttcatcagca attattaaat aaaatttatt gtatttaagt attcgattta tcatttaaaa
     7921 attttattac aatatctatt ttgttttgct cgttcattat gtctattgaa cttccataat
     7981 cactttttaa tttatctaga ccacttttgc ttatttctcc ttctggaagt atacttaatt
     8041 ctagatattt ttcatgacca ggagatgaca ttaatagata tgaaccatta taaggcatac
     8101 ctaaattttc tattttatct gctaatgggt catctttaaa gccaccattt attattattt
     8161 ttccatcttt ctttacccat gatatcattc ctccatcagt atattttgat tcatctgcat
     8221 agtagctaag agacgcactt tttattgcac ttatatcagc ttcaagttta gctatctttg
     8281 ctttttctat atttttaaat aatgctggaa gtgctactat tgccaatatt cctattatag
     8341 caattactac taataattcc actagagtaa atcctttttt atttttcatt tatttcccct
     8401 ccatataaaa ttaataatat ataaattttt attttgttga tttctacttt ctatatttta
     8461 ccatatatag acaaaaaaat cactttctat gacaaatata ctattatttt acaatttatg
     8521 gaaatgattt aaaatgacat ttcttgttag aaaagatata agaaatggat taaaataaag
     8581 aaaactacag tcatatcaat gtcaataata ttatttaaaa gcagatgaaa ataaaaagag
     8641 gactcagaaa ataatgtcta tttaattata cttacttacc aatacc
//
LOCUS       DAEPHU010000116         8593 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 01A10CD0081
            SAMN05941466-rid12468953.denovo.117, whole genome shotgun sequence.
ACCESSION   DAEPHU010000116 DAEPHU010000000
VERSION     DAEPHU010000116.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941466
            Sequence Read Archive: SRR6291087
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 8593)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8593)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068158.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 22:43:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,892
            CDSs (total)                      :: 3,805
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 87
            rRNAs                             :: 8, 1, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 55
            CDSs (without protein)            :: 55
            Pseudo Genes (ambiguous residues) :: 0 of 55
            Pseudo Genes (frameshifted)       :: 21 of 55
            Pseudo Genes (incomplete)         :: 28 of 55
            Pseudo Genes (internal stop)      :: 16 of 55
            Pseudo Genes (multiple problems)  :: 8 of 55
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8593
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941466-rid12468953.denovo.117"
                     /strain="01A10CD0081"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            complement(184..1860)
                     /gene="bclA2"
                     /locus_tag="KR231_003500"
     CDS             complement(184..1860)
                     /gene="bclA2"
                     /locus_tag="KR231_003500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="collagen-like exosporium glycoprotein BclA2"
                     /protein_id="HBH0005828.1"
                     /translation="MSDISGPSLYQDVGPTGPTGATGPTGPTGPRGVTGATGANGITG
                     PTGNTGATGANGITGPTGNMGATGPNGTTGSTGPTGNTGATGANGITGPTGNTGATGA
                     NGITGPTGNKGATGANGITGSTGPTGNTGATGANGITGPTGNTGATGATGPTGLTGAT
                     GATGANGITGPTGNTGATGANGVTGATGPTGNTGATGPTGSIGATGATGTTGATGPIG
                     ATGATGADGEVGPTGAVGATGPDGLVGPTGPTGPTGATGANGLVGPTGPTGATGANGL
                     VGPTGATGATGVAGAIGPTGAVGATGPTGADGAVGPTGATGATGANGATGPTGAVGAT
                     GANGVAGPIGPTGPTGENGVAGATGATGATGANGATGPTGAVGATGANGVAGAIGPTG
                     PTGANGATGATGATGATGANGATGPTGATGATGVLAANNAQFTVSSSSLVNNTLVTFN
                     SSFINGTNITFPTSSTINLAVGGIYNVSFGIRATLSLAGFMSITTNFNGVTQNNFIAK
                     AVNTLTSSDVSVSLSFLVDARAAAVTLSFTFGSGTTGTSAAGYVSVYRIQ"
     gene            complement(2238..2777)
                     /gene="hpt"
                     /locus_tag="KR231_003501"
     CDS             complement(2238..2777)
                     /gene="hpt"
                     /locus_tag="KR231_003501"
                     /EC_number="2.4.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypoxanthine phosphoribosyltransferase"
                     /protein_id="HBH0005829.1"
                     /translation="MDIETKKWEVLYSEEKIKDKLRELGAIIEKDYKDKNLMVVSLLK
                     GSFIFCADLVRNINLPLRVNFMTTSSYGNNEESTGKVKVVSDVTTDIAGYDVLVVDDI
                     TDSALTMDFVLKHLKAKNPASLKCCVLLDKPSRRKVDLVPDYCGFEIEDKFVVGYGFD
                     FGDYYRNVPYIFNVTDEDR"
     gene            complement(3105..4412)
                     /locus_tag="KR231_003502"
     CDS             complement(3105..4412)
                     /locus_tag="KR231_003502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454042.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine dehydratase subunit alpha family protein"
                     /protein_id="HBH0005830.1"
                     /translation="MRDIRKELVEMLKAEVKPAVGCTEPVALALACAKAKELLGEEIV
                     ENRMLVSPSIYKNGMCVGIPGTERLGLKIAAALGIVGGHSENGLSVLETLTKEEVKIA
                     EDYMDNTPLSITPADTREKVFIEVVLKGKNHIAKVRIRTKHDNFTFLEKDGEVLLDNE
                     PKVSASNDAAEKAESLMDTVTIQELIKNVEGIDFKDIEFLLDGVKMNEEMAEYGLKQK
                     TGIGVGYGIKKSIEEGLLGNDVINYAMMLTAGASDARMAGVKMPVMSSNGSGNHGLTA
                     ILPIVAYNKKFPQSDERLAKALAISHLVTGYIKNYTGRLSAVCGCGVAASTGATAGIS
                     WLMNGTEKQIEGAIENMIADLSGMICDGAKAGCALKLSSAASAAIQSAIIAKQDCFVP
                     PLNGIVGSSVEQSIQNLGRVSDKGMSITDEIILNVMNDMNKVD"
     gene            complement(4837..6612)
                     /locus_tag="KR231_003503"
     CDS             complement(4837..6612)
                     /locus_tag="KR231_003503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HBH0005831.1"
                     /translation="MMIMIGLEYIKSDIQNIAEAIVSVLNIDVTIVNKELFRIAGTGV
                     YIDKIGEKVDKYTAFKKSLTEQITILIDDPKSSDICRECYKSGACVEFAEVCCPIICD
                     GVSHGVIGLIAFTKEQAQIIENNKSGLINFLGKMADLISNKLKAQIKTYELELEKKKL
                     ETLLNNMDKAVVSIDVDGKIDKYNSKFKELFNIKDSITGKNIFVELDFIKKPSINNFK
                     KDKSCSFFYKRYGYDSKGIYNINKIVLKNELKGYVIDFIDKRDAIKNYNKMNKDYRIK
                     LENIIGESVAIRNSKKEALIASKSTSTVLITGESGTGKELFARAIHNHSNRVDNPFIA
                     VNCAAIPDNLLESELFGYEEGAFTGAKKGGKLGMFEVAHKGSIFLDEIGDMSLHLQSK
                     LLRVLQEKELNKIGSKSNVSIDVRIIAATNKDLEKMVQNGTFREDLYYRLNVIPIKLP
                     SLRERKEDIPLIIKHMVKEYSKKLDKNVIDIDSRVVDAMMEYKWPGNIRELQNIIEYS
                     VNMSSSSIITMNVIPQKIKNTSVEELEVKSDRIIPLDELEKIEIIKALNKYKDYKKDK
                     ELTAKALGISRATLYRKIEKYNIIS"
     gene            complement(6609..6746)
                     /locus_tag="KR231_003504"
     CDS             complement(6609..6746)
                     /locus_tag="KR231_003504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0005832.1"
                     /translation="MEINYELIIIVMLFVILMSIQFTLNKIYLILKEIRQILMLKKNK
                     E"
     gene            complement(6824..7393)
                     /locus_tag="KR231_003505"
     CDS             complement(6824..7393)
                     /locus_tag="KR231_003505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HBH0005833.1"
                     /translation="MKSILCQINKQPVKAKYTSDELECFLDTIEYNVGDKILLVGHIG
                     NLGKRLRGLGTSVTILENSNYEDVCYSLVYNENCNVVKGKLEFLPFDDNQFNKIIIVD
                     QFNVITDCEKASSEIQRVLKGNGEVILEDLNLKNLKVKLNYLKHKFCGSVAKIHYPHE
                     VFNIFSRLNFDGMIKESNKLKYIYVGKRR"
     gene            complement(7577..8212)
                     /locus_tag="KR231_003506"
     CDS             complement(7577..8212)
                     /locus_tag="KR231_003506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HBH0005834.1"
                     /translation="MIAVKDENNVVNLRGELDNKLEFSHEIFGEKFYNMKIKINRLSD
                     SFDILPMTVSERLLQDIDLDKQNLVNVVGQLRSYNKTLNNKNRLVLTVFVREIKSIDE
                     ENKDPNSIFLDGYVCKEPVYRKTPLGREITDLLVAINRPYNKSDYIPSIVWGRNAKFA
                     KNLKVGDRIQLWGRVQSREYEKKIDENNVVKKMAYEVSISKIKKLDENNNE"
BASE COUNT         2476 a         1691 c          963 g         3463 t
ORIGIN      
        1 ttattatttt atagtctttt catcatataa acctattaaa tattatccta tttattggta
       61 tatgaaatca tattgtttat tattttatag tcttttcatc atataaacct attaaatatt
      121 attctattta ttggtatatg aaatcatatt gtttattatt ttataatctt ttcatcatat
      181 aaactattgt attctataaa ctgatacata tccagctgca gaagtacctg tcgtgcctga
      241 accaaatgta aaacttaaag taacagctgc tgctctagca tcaactaaaa agcttaaact
      301 tacacttaca tctgatgaag taagtgtatt tactgctttt gcaataaagt tattttgagt
      361 tactccatta aagttagtag taattgacat aaatcctgca agtgaaagtg tggcacgtat
      421 accgaaagat acattgtata tccctccaac tgcaagattt atagtactac ttgttggaaa
      481 agttatatta gttccattta taaatgatga attaaatgtc actaatgtat tattcactaa
      541 acttgaagag gacactgtaa attgtgcatt gtttgctgct aacactcctg ttgctcctgt
      601 cgctccggtt ggacctgttg ctccatttgc tccggttgct cctgtcgccc ctgttgctcc
      661 tgtcgctcca tttgctccgg ttgggcctgt tggtcctatc gctcctgcta ctccatttgc
      721 tcccgttgct cctactgctc ctgttgggcc tgttgctcca tttgcccctg ttgctcctgt
      781 cgctcctgtt gctcctgcta ctccattttc tcccgttgga cctgttggac ctattggacc
      841 tgctactcca ttcgctcccg ttgctcctac tgctcccgtt gggcctgttg ctccatttgc
      901 ccctgttgct cctgtcgctc ctgttggacc tactgctcca tctgctcccg ttgggcctgt
      961 tgctcctact gctcccgttg gacctattgc cccagctact cctgttgctc ctgtcgctcc
     1021 tgttggacct accaaaccat ttgctccggt tgctccggtt gggcctgttg ggcctaccaa
     1081 accatttgct ccggttgctc cggttgggcc tgttgggcct gttggaccta ccaaaccatc
     1141 tggacctgtt gctcctactg ctcctgttgg acctacctct ccatctgctc ctgttgctcc
     1201 tgttgctcct attggacctg ttgccccagt tgttcctgtt gctccagtcg ctcctatact
     1261 tcctgttgga cctgttgctc ctgtatttcc tgttgggcct gtagcacctg ttactccatt
     1321 tgctccggtt gctcctgtat ttcctgttgg tcctgttatt ccatttgctc cggttgctcc
     1381 tgttgctcca gttagtccgg ttggtcctgt tgctcctgtt gctcctgtat tccctgttgg
     1441 acctgttatt ccatttgctc cagtcgctcc tgtatttcct gttggtcctg tagaacctgt
     1501 tattccattt gctccggttg ctcctttgtt tcctgttggt cctgttattc catttgctcc
     1561 ggttgctcct gtattccctg tcggacctgt tattccattc gctccagtcg ctcctgtatt
     1621 tcctgttggt cctgtagaac ctgttgttcc atttggtcca gtcgctccca tatttcctgt
     1681 tggacccgtt attccattcg ctccagttgc tcctgtattt cctgttggtc ctgttattcc
     1741 atttgctccg gtcgctccag ttacacctct aggccccgtc ggtcctgttg gaccagtagc
     1801 acctgttggc cctgttggac ctacatcttg atataaactt ggacctgaaa tatcactcat
     1861 ataattaatc ctcctttttt aaagttagag taatactcta taaatattga gtattactct
     1921 atataattat atgaatcgac aatttcttat gtgataatgt atctatttgc ttatatcaac
     1981 atatatgctt tgattcttaa atttcattac ttttttgtaa aatcttttac aattattagt
     2041 actcttttac aattattaat acaattaaaa aactcatttc ccatcaatta tttaaaattt
     2101 ttttattatg ctataaaaaa tagataatta aattgcataa aattaattta atactacttt
     2161 aattactttt taaataaaaa aacctcaaca cgattaataa aaatcatatt aaggcatcca
     2221 caaaattata taattgctta tctatcttca tcagtaacat tgaatatata aggaacattt
     2281 ctataataat caccaaaatc aaacccatat ccaaccacaa acttatcttc tatttcaaat
     2341 ccacaataat ctggcactaa atcgactttt cttctgcttg gtttatccaa aagaacacag
     2401 cattttaaac tagcaggatt tttagctttt agatgtttta acacaaaatc catagtaagt
     2461 gcagaatcag taatatcgtc tacaaccaaa acatcatatc ctgctatatc agtagtcaca
     2521 tctgaaacta ctttaacctt tccagtactt tcttcattgt ttccataact agatgtagtc
     2581 ataaaattaa ctctaagtgg taagtttata tttctaacta agtctgcaca aaatataaag
     2641 ctacctttta atagagaaac taccataaga tttttatctt tataatcttt ttctataatt
     2701 gctcctaatt cccttaattt atctttaatt ttttcttctg aatacaatac ttcccatttt
     2761 tttgtttcta tatccataaa aagacctcca attgtaataa tccttcttaa ttttataaga
     2821 gattgctcac tttttcaata ctcttattca atattagtca atattattga gtttttatgt
     2881 tcattcaaca attattaaca atgtatctta tattttaagt agttcatata tccacactaa
     2941 attacatact atatatttta gacaaaaaaa gaaaaaactt gcattaacaa gttttttcta
     3001 ttatacataa atttatacat aatcatattt tattagaggg tactaattaa atttatttat
     3061 gctatttttg ttatacctca taatacaaaa catattataa agtactagtc aactttattc
     3121 atatcattca ttacatttaa gattatctca tctgttatag acataccttt gtcacttact
     3181 ctacctaagt tttgtatact ttgctcaaca cttgaaccaa ctataccatt tagtggtggt
     3241 acaaaacaat cttgcttagc tattatagca ctttgtatag ctgcagatgc tgcagaagat
     3301 aattttaatg cacaaccagc tttcgcaccg tcacatatca ttccacttaa gtcagctatc
     3361 atattttcta tagctccttc tatttgcttt tcagtaccat tcataagcca agagatacca
     3421 gcagttgctc cagtagaagc agcaacacca catccacata cagcagataa tcttcctgta
     3481 tagttcttaa tataaccagt tactagatga gatatagcta aagcttttgc tagtctttca
     3541 tcagattgtg ggaatttttt attataagca acgattggaa gaattgctgt taatccatga
     3601 tttccacttc catttgaact cataacaggc atttttaccc ctgccattct tgcatctgaa
     3661 gctccagcag ttaacatcat tgcataattt ataacatcat tacctaaaag accttcttct
     3721 atagactttt taattccata tcctacacca ataccagttt tttgttttaa tccatattca
     3781 gccatctctt cattcatttt tactccatct agtaaaaatt ctatatcttt aaaatcaatt
     3841 ccttctacat tttttattaa ttcttgtata gttactgtat ccattaaact ttcagctttt
     3901 tctgccgcat catttgaagc tgatactttt ggttcattgt ctaataatac ttctccatct
     3961 ttttctaaga acgtaaaatt atcatgttta gttcttattc tcactttagc aatatgattt
     4021 tttcctttta acacaacttc tataaatact ttctctcttg tatcagcagg tgttattgat
     4081 agtggagtat tatccatata atcctcagct attttaactt cctcttttgt tagagtttct
     4141 aacacactta atccattttc agaatgtcca cctactatac ctagagctgc tgcaattttt
     4201 aatcctaatc tttcagtacc tggtatacct acgcacatac catttttata aatactagga
     4261 ctaactaaca tacgattttc aactatttct tctcctaata attcctttgc ctttgcacat
     4321 gctagagcta aggctactgg ttcagtacac cctactgctg gtttaacttc tgcctttaac
     4381 atttccacta attcttttct tatatctctc attatatata aacctcccaa ttaagtttag
     4441 atttagtact caaataatta attaaataat ttcttatcta tatttatagc aaaatacatg
     4501 ccatattttt tatatctttt tatattttta gtcttatatt ctataaccat tggtatgact
     4561 gcctctattt atgtattttt tttatttgta tagagtattt atattcttta aaatggagaa
     4621 acatatgaca atttcgcaaa aagacaaaaa aaagtctcaa aatgagattc tatatcattt
     4681 tgagacggct caaatatatt attttttaac ttataaaaac cattttttaa ttcataaaaa
     4741 aagattctgc aaaacactta tagtataagt ttaaagcttt ctttaaagtt atgaatttag
     4801 aaaaatttaa attttatata gctttttatt atattactat gaaattatat tgtatttttc
     4861 aatttttcta tataatgtag ctcttgatat tccaagtgct ttagctgtta attctttatc
     4921 ttttttataa tctttgtact tatttaaagc ttttattatc tcaatcttct ctagttcatc
     4981 aagtggaatt atcctatcgc ttttaacttc taactcttct acagaggtat tcttaatttt
     5041 ttgaggaatt acattcattg taattattga agaagaagac atattcacac tatattcaat
     5101 aatattctgc aactctctta tattccctgg ccacttatat tccatcatag catcaacaac
     5161 cctgctatct atgtcaataa catttttatc taattttttt gaatactctt taaccatatg
     5221 cttgattata agtgggatat cttcttttct ctctcttaaa cttggtaatt ttataggtat
     5281 aacatttaat ctatagtata aatcttctct aaaagtgcca ttttgaacca ttttttctaa
     5341 atctttattt gtagcagcaa taattcttac atctattgaa acatttgatt tacttccaat
     5401 tttattaagt tccttttctt gtaatactct caataacttt gactgtaaat gcaaactcat
     5461 atctcctatt tcatctaaaa atatacttcc cttatgagct acttcaaaca ttccaagctt
     5521 tccacctttt ttagctccag taaaagctcc ctcttcatat ccaaataatt cactttctaa
     5581 taaattgtct ggtatagcag cacagtttac agctataaaa ggattatcta ctctattgct
     5641 atggttgtgt atggctcttg caaatagctc cttacccgtt ccactttccc cagtaataag
     5701 tactgttgat gttgatttag aagctattag ggcttccttt ttagaatttc ttatagctac
     5761 actttctcca attatgtttt ccaattttat tctataatct ttattcatct tattgtagtt
     5821 ttttatagca tctcttttat ctataaaatc aataacatat ccctttaact cattttttaa
     5881 tactatttta ttgatgttgt atattccctt cgaatcatat ccgtatcttt tataaaaaaa
     5941 actacaggat ttgtctttct taaagttatt tatagaaggt ttctttataa aatctaattc
     6001 gacaaatatg tttttgccag ttatactatc ctttatattg aaaagctctt taaattttga
     6061 attatattta tcaatttttc catccacatc aatagacaca acagctttgt ccatattgtt
     6121 taacagtgtc tctaattttt tcttttctaa ttcaagctca taagttttaa tttgagcttt
     6181 taatttatta gatattaagt ctgccatttt gcctaaaaag tttataagac cacttttatt
     6241 attttctata atctgtgctt gttcctttgt aaaggctata aggcctataa caccatgaga
     6301 gactccatca catataatgg gacaacacac ctctgcaaac tctacacaag ccccactttt
     6361 atagcattcc ctacatatat cactactctt tgggtcatca attagtattg taatctgctc
     6421 tgtaagtgat tttttaaaag ccgtatattt atctactttc tcacctattt tgtctatata
     6481 tactcctgta cctgcaatcc taaataactc cttatttact atagttacat ctatattgag
     6541 tactgatact atagcttcag ctatattttg aatatcagat tttatatatt ctaaacctat
     6601 cataatcatc attccttatt tttctttaac ataagtattt gtcttatttc tttaagaatc
     6661 aagtatatct tatttaaagt aaattggatt gacatcagga ttacaaagag cataacaatt
     6721 attattaact cataatttat ttccatctaa acatctcctt ataacaaaag actaggctta
     6781 acctagtctt ttatattata tccatattta tattttaact catttatctt ctttttccca
     6841 cataaatata ttttaattta tttgactctt taatcatacc atcaaagttt aatcttgaaa
     6901 atatattaaa tacttcatgt ggatagtgaa tctttgcaac agaaccacaa aatttatgtt
     6961 taagatagtt taacttaact tttaaattct ttaaatttaa atcctctaat ataacctctc
     7021 cattgccctt taacactctt tgtatttcag atgaagcttt ttcacaatct gtaataacat
     7081 taaattggtc aactattatt atcttgttga actgattatc atcaaatggt agaaactcta
     7141 acttaccttt aactacattg caattttcat tatacactag agaataacag acatcttcat
     7201 aattactatt ctccagtata gttacagaag ttccaagacc tctcaatctc ttgcctaggt
     7261 ttcctatatg accaacaagc aatattttat cacctacatt atactcaatt gtatccaaaa
     7321 aacattctaa ttcatcagat gtatatttag ctttaaccgg ctgtttattt atctgacata
     7381 atatgctttt cacaatgctt cacctcttca tttcctcaat tataaattat gtacagatta
     7441 cattataata aatggcgagc aactattcaa gagatatttc attagtattt ttttaaacaa
     7501 tctttataca ttttaatatg atattatacc aaatttatta ggattttatt cataaaaatc
     7561 agtctatttt ttatgtttat tcattgttat tttcatccaa tttttttatt ttcgatatgg
     7621 atacttcata tgccattttt ttgaccacat tattttcatc tatttttttc tcatattctc
     7681 tactttgaac cctaccccaa agctgtattc tatcaccaac ctttagattc tttgcaaatt
     7741 tagcatttct accccaaact attgatggta tataatcaga tttattataa ggtctgttta
     7801 tagcaactaa taaatcggtt atttcccttc ctaaaggtgt cttcctatac acaggttcct
     7861 tacatacata tccatctaaa aatatactat tagggtcttt attttcctcg tctatgcttt
     7921 ttatttctct gacaaacact gtaagcacta atctattttt attatttaat gttttgttat
     7981 atgatcttaa ttggcctacg acattgacta aattttgttt atcaaggtca atatcttgga
     8041 gaagtctttc tgatacagtc attggaagta tatcaaaaga atcgcttagt ctgtttattt
     8101 ttattttcat attataaaat ttttctccaa atatctcatg gctaaattct agcttattgt
     8161 ctaactcccc tcttaagttt actacgttat tctcatcttt aacagctatc atattttatc
     8221 cctccacaat tgttaattct tatatttctg gtatcagctt atataataaa tatatttata
     8281 agggatgtat tttattacaa atctttgatt gctgtttaaa agtttttatt tagttataaa
     8341 tttcatttaa tatttcactt ttataattat aaaattatta tctttttgta ccacatatac
     8401 taattaaact acctatttca gttttgtatt aattataaaa atcctattat atagttaata
     8461 agtcatatat aacttaaatt tattcactct atataagcaa cttcaacgaa ttaaatttat
     8521 tcaaataatt cagatgaata ttgagtcatt ataaacttat ttttcttaat tataagttat
     8581 attagactta tta
//
LOCUS       DAEPHU010000117         8214 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 01A10CD0081
            SAMN05941466-rid12468953.denovo.118, whole genome shotgun sequence.
ACCESSION   DAEPHU010000117 DAEPHU010000000
VERSION     DAEPHU010000117.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941466
            Sequence Read Archive: SRR6291087
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 8214)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8214)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068158.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 22:43:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,892
            CDSs (total)                      :: 3,805
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 87
            rRNAs                             :: 8, 1, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 55
            CDSs (without protein)            :: 55
            Pseudo Genes (ambiguous residues) :: 0 of 55
            Pseudo Genes (frameshifted)       :: 21 of 55
            Pseudo Genes (incomplete)         :: 28 of 55
            Pseudo Genes (internal stop)      :: 16 of 55
            Pseudo Genes (multiple problems)  :: 8 of 55
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8214
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941466-rid12468953.denovo.118"
                     /strain="01A10CD0081"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            179..520
                     /locus_tag="KR231_003507"
     CDS             179..520
                     /locus_tag="KR231_003507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LytTR family transcriptional regulator"
                     /protein_id="HBH0005835.1"
                     /translation="MKEENFINVEYEDKRFSINSKEVLYIEKQEYEVKIYTESGNYEV
                     GENAPCIRKLLKEENFFKCSNSYIVNLDKCEFYLSNNCIFVNNNFIRILGSERKKKLK
                     KKLEKLYDYED"
     gene            671..1084
                     /locus_tag="KR231_003508"
     CDS             671..1084
                     /locus_tag="KR231_003508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1653 domain-containing protein"
                     /protein_id="HBH0005836.1"
                     /translation="MLELKNNLGISERKLKYPCIYKHFKGKYYATMGLSKAIDHIENI
                     CEIYGKENLIQNRNKYKLVIRHTEREEDIYVYRDLDGNFYHKKEEDTNDLVLYKTLYD
                     DTGIFARPLDMFLEKVDTDKYVNSIQEYRFEEVYK"
     gene            1286..1927
                     /locus_tag="KR231_003509"
     CDS             1286..1927
                     /locus_tag="KR231_003509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902783.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HBH0005837.1"
                     /translation="MGNTFYIVRHGQTDWNILGKTQGHGNSDLTPQGIEQAKELSEDI
                     GKYSIDYIFSSDLGRAMQTAQILGDKLNIEVQKTEALREMGFGVWEGLLIKEIQKDYS
                     DIYATWRNEPHLVNIPEGETLKIIKERVDAFIKELNEKYDNKNIILVTHSITLRVMLL
                     SFLESGMENIYRIKQDNTALNIVEFKDYGPVIVKMNDTSHIKNHVKINNSALE"
     gene            1951..3204
                     /locus_tag="KR231_003510"
     CDS             1951..3204
                     /locus_tag="KR231_003510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HBH0005838.1"
                     /translation="MSKVIVVGGGASGMMAALSASKNNNEVILVERNGELGRKLRATG
                     GGRCNFTNNREIEDFFDKVVSNKKFLYSSFYTFTNKDLISYFESRNLEYKIEEENDHK
                     VYTKNDKSIEVIEVLNKDLLNHNVKIMYNKKVIDIITEEIALKDDSNKDKSKYLIKGI
                     ILDNGDKILGDKVIISTGGVSYSKTGSDGSMYKILKKHGHTLNKLYPALVPLTIEEKW
                     IKDLQGISMKNVEISCKIKKRKISKSGDMLFAHFGITGPCVLIMSSYINKIIEKEKVE
                     LNIDFLPNLSTDEISSIIRAFPNKNVLNNLKQILPQNFLKEIFSLLSLVDKKASDLSK
                     ADEIRIIEYIKNMKLTCNGTTGINTGMVTSGGISVKEINSSTMESKLVKNLFFTGEVI
                     DIDAETGGYNLQIAFSTGYLAGISV"
     gene            3250..3900
                     /locus_tag="KR231_003511"
     CDS             3250..3900
                     /locus_tag="KR231_003511"
                     /EC_number="2.7.4.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="(d)CMP kinase"
                     /protein_id="HBH0005839.1"
                     /translation="MGNLVIAVDGPAGAGKSTIAKIVAKKLNINYIDTGAMYRAVTYK
                     CLKSGIDVNNEKEVIQIAENSDIDFKDNNIYLDKEVINEEIRTIEVSNNVSNVAKIKE
                     VRQLMVEVQRKIGMKNSVILDGRDIGSYVFPDADYKFFLVATPEERGNRRYKELCNKG
                     YNTTLEEVIEDIIRRDEIDSNREFAPLVKANDALEIDTTGKTIEEVVEEVVSKINL"
     gene            3951..4547
                     /locus_tag="KR231_003512"
     CDS             3951..4547
                     /locus_tag="KR231_003512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-acyl-sn-glycerol-3-phosphate acyltransferase"
                     /protein_id="HBH0005840.1"
                     /translation="MNFYRFVINIFKGFSKIFFKYEVIGAENIPDRGNIVIASNHKSN
                     LDPIFLAAAIENREIAAIAKKELFKVKPLGFILKKLHVMPINREKPDVSTIKTILRSV
                     RDGYVLGIFPEGTRIKGDSFGKAKAGLSVFTIKSKSKVVPVSIISKYKLFSKVIVYIG
                     EPISFEEHFKEKLSNDDHERISQEILEVIKQNYFKYSK"
     gene            4560..5399
                     /locus_tag="KR231_003513"
     CDS             4560..5399
                     /locus_tag="KR231_003513"
                     /EC_number="1.17.7.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-3-methylbut-2-enyl diphosphate
                     reductase"
                     /protein_id="HBH0005841.1"
                     /translation="MNIKIAKNAGFCFGVKRAMKMAWDEVEKNDSGIYALGPLIHNKQ
                     AVAKYEEKGLKTVNEIDTIPNHENMIIRSHGVPENIYKEAKDKKLKIVDTTCPFVKKI
                     HTVVSEYHNKGYEIIVIGDMKHPEVIGINGWCENSAIIIKTLEQMENMEFDNSKRYCL
                     VAQTTINPELYISIVNKLSDKLEEIVFNDTICSATKTRQESAKELAKKVDCMIVIGGK
                     HSSNTQKLVKVCEDLVPTFAIETKDELDVNTLKKYKNLGITAGASTPNWIIEEVVTFL
                     ENL"
     gene            5644..6798
                     /locus_tag="KR231_003514"
     CDS             5644..6798
                     /locus_tag="KR231_003514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenic efflux protein"
                     /protein_id="HBH0005842.1"
                     /translation="MEMLISASEEAFLHVGSMIGFFILLFGYINYKTSGNFTNIISKN
                     RKFQPLIGALIGAIPGCGGSLAIMPLYINGKLSFGAIIASLIASMGDAAFVLISSNIK
                     MYFFVTIVSTITGIITGQLVDYFKLEEKLGLKNRRKSDKYDISKNNPKENKEQHNHDE
                     IILDTLAKSHGNTNRLAFIITHGKGYKIYIGIIVIGFIFMSLAHSGLNLPIIEKLHSL
                     EEVIAVIGILFSIIYMWCFKKVFKNSNQKEEENKKISLREMLIHSVGEISFVITWIFI
                     AYLIYDLIILILGGDEYLVKLVLSTGVISVFIGAGLGLIPGCGIQIVLMSFYLKGTIP
                     LGAVIANSISQDGDALFPLLAMDKKSSLWAMIITTIPAILVGMIVYAFLG"
     gene            7104..7280
                     /locus_tag="KR231_003515"
                     /pseudo
     CDS             7104..7280
                     /locus_tag="KR231_003515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728625.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="adenine deaminase"
     gene            7929..>8214
                     /locus_tag="KR231_003516"
     CDS             7929..>8214
                     /locus_tag="KR231_003516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBH0005843.1"
                     /translation="MIVVEKAYKFRMYPNKKQQELINKTFGCCRFVYNKYLAKRIDVY
                     KKHKETFTYKQCSSDLTNLKKELKWLKEPDKFSLQNALRDLDNAYKKFFKE"
BASE COUNT         3425 a          792 c         1419 g         2578 t
ORIGIN      
        1 ataattaaaa aaagtctttt taactttaaa aattaatgtt aaaaaataaa cttatacatt
       61 aatattaata ataattattt aaatatctta agtaaatcag tcttacatat atttccgata
      121 gattatattg ataaaaaaca ctaaaattaa attaataaaa gtacttggag ggatggaaat
      181 gaaagaggaa aattttatta atgttgaata cgaggataaa cgtttttcaa ttaatagtaa
      241 agaagttttg tacatagaaa agcaagagta tgaagtaaag atttatactg aaagtggtaa
      301 ttatgaagtt ggagaaaatg ctccttgtat aagaaaacta ttgaaagaag aaaatttttt
      361 caaatgcagt aatagttata ttgtaaatct agacaagtgt gaattttatc tcagcaataa
      421 ttgtattttt gtgaataata attttataag aattttaggt tcagaaagaa aaaagaaatt
      481 aaaaaagaaa ttagaaaaat tatatgatta tgaagattaa tattgggagg ctgtatttta
      541 tacagcctct ttatttattg attgtattat taataaattt taaattatga taaaatataa
      601 aacaagtaac ttatttcaga ataaaatact ttttaaaaga aagggacgag atatgggaga
      661 ttataataaa atgcttgaat taaagaataa cttaggtatc agtgaaagaa agttaaaata
      721 tccttgtatc tataaacatt tcaaagggaa atattatgct acaatgggtc ttagcaaggc
      781 tattgatcat atagaaaaca tatgtgaaat atatggtaaa gaaaatttaa tccaaaacag
      841 aaataaatat aaattagtta ttagacatac tgaaagagaa gaagatatct atgtttatag
      901 ggatttagat ggaaactttt atcataaaaa agaagaagat actaatgatt tagttttata
      961 caagacctta tatgatgata caggaatatt tgcaagacct ttggatatgt ttttagaaaa
     1021 agtagataca gataagtatg tcaattcaat tcaagaatac agatttgaag aagtatataa
     1081 ataatataag agaaatatgt ttataaattt agaaaaattc tttaacagta caataatttg
     1141 cagaaataca aatgagattt attgtaaata atatgttaga ttagattata aaatagaaac
     1201 aaagtaaagt attatatgat ataattaagt tttgagaagt gataatttat atttaataaa
     1261 aaataggcat atattaggag gacatatggg aaatactttt tatatagtaa gacatggaca
     1321 aacggattgg aatatattgg gaaaaacaca aggtcatggt aattctgacc ttacgcctca
     1381 aggtatagaa caggcaaaag aactttctga agatattggc aagtattcaa ttgattatat
     1441 ttttagtagc gaccttggga gagcaatgca aacagctcaa attttaggag ataagctcaa
     1501 tattgaagtt caaaaaactg aggcacttag agaaatggga ttcggagttt gggaaggcct
     1561 tttaataaaa gaaattcaaa aagattattc agatatatat gcaacatgga gaaatgaacc
     1621 acacttagta aatataccag aaggcgaaac tcttaagatt ataaaggaaa gagtagatgc
     1681 ttttataaag gaactaaatg aaaaatatga taataaaaat ataattcttg ttacacattc
     1741 aattacattg agggttatgt tgttgtcatt tttagaatca ggtatggaaa atatatatag
     1801 aattaagcaa gataatactg ctttaaatat agtagaattt aaagattatg ggcctgttat
     1861 agtaaaaatg aatgatacaa gtcatataaa aaatcatgta aagataaata attctgcact
     1921 ggagtaggaa tcaattataa ggagaaattt atgagtaaag ttatagtagt tggtggagga
     1981 gcttctggaa tgatggcagc tttgtcagct tcaaaaaaca ataatgaagt aatattagtt
     2041 gagagaaatg gagaattagg aagaaaactt agggcaactg gtggcggtag atgcaatttt
     2101 accaataata gagagataga agattttttt gataaagttg tcagtaataa aaaatttctc
     2161 tatagtagtt tctatacatt tacaaataaa gaccttattt cgtattttga aagtagaaat
     2221 ttggaatata agattgaaga agaaaatgac cacaaagtat acactaaaaa tgataaatct
     2281 atagaagtaa tagaagtatt aaataaagat ttactcaatc acaatgtaaa gataatgtat
     2341 aataagaaag ttatagatat tataactgaa gaaattgctc taaaagatga ttctaataag
     2401 gacaagtcaa agtatctaat aaaagggatt attttagata atggagataa aatactagga
     2461 gacaaggtta ttatatcaac tggaggagtg agttattcaa agacgggttc agatggttca
     2521 atgtataaga ttcttaaaaa gcatggacat acattaaaca aactatatcc tgctttagtt
     2581 ccacttacaa tagaggaaaa atggattaaa gatttacaag gaatatccat gaagaatgtg
     2641 gaaatatctt gtaagattaa gaaaaggaaa atatcaaaat ctggagacat gctatttgcc
     2701 cattttggga taacaggacc ttgtgttctt ataatgtctt cttatattaa caagattatt
     2761 gaaaaggaaa aggtagaatt aaatatagat ttcttaccaa atttaagtac tgatgaaatc
     2821 tctagtataa tcagagcatt tccaaataaa aatgttctaa ataatcttaa gcaaatacta
     2881 cctcaaaatt tcttaaaaga gattttttct ctattatctt tagttgataa aaaggcaagt
     2941 gatttgtcta aggcagatga aattagaatt attgagtata taaaaaatat gaagctaact
     3001 tgtaatggga ctacaggtat aaacactggt atggttactt ctggtggtat ttcagttaaa
     3061 gaaattaatt cttctactat ggaatctaaa ttagttaaga acttattttt tacaggtgaa
     3121 gtaattgata tagatgcaga aactggtgga tataatttac aaatagcatt ttcaactgga
     3181 tatcttgcgg gtataagtgt ataaatataa ttttttaata attaaatatg aataaataga
     3241 ggtgtatata tgggtaattt agttatagct gtagatggtc cagcaggagc tggaaaaagt
     3301 acaatagcca agatagtagc aaaaaagcta aatataaatt atatagatac aggtgctatg
     3361 tacagagcag ttacttataa gtgtttaaaa agtggtattg atgtcaataa tgaaaaagaa
     3421 gttattcaaa tagctgaaaa ttcggatata gattttaaag ataacaatat atatttggac
     3481 aaagaagtta taaatgaaga aataagaaca atagaagtaa gcaataatgt ttctaatgta
     3541 gcaaaaataa aagaagtaag acagttgatg gttgaagttc aacgaaaaat aggaatgaaa
     3601 aattcagtaa tactagatgg tagagatata ggttcatatg ttttcccaga tgcagattac
     3661 aaattctttt tagtagctac tccagaagaa agaggaaata gacgctataa agaactttgt
     3721 aataaaggat ataatactac tttagaagaa gtaattgagg atataataag acgagatgaa
     3781 attgattcaa atagagaatt tgcaccattg gtaaaagcta atgatgcact agaaatagat
     3841 actacaggaa aaactataga agaagttgta gaagaagttg tatctaaaat aaatctttag
     3901 ttttttatgc atcataatga aaataaatgt agtgttgaag ggagataaac gtgaattttt
     3961 atagatttgt aataaatatt tttaagggtt tttctaaaat attttttaaa tatgaagtta
     4021 taggtgcaga gaatattcca gatagaggaa atatagtaat agcatcaaat cataaatcga
     4081 atcttgaccc tatattcttg gctgctgcca tagaaaatag agaaatagct gcaattgcaa
     4141 agaaagaatt gtttaaagta aaaccattgg gatttatatt aaaaaaattg catgttatgc
     4201 ctataaatag agaaaaacca gatgtatcta caataaaaac tattttaagg tcagttagag
     4261 acggttatgt attaggaata tttccagagg gtactagaat aaaaggagat tcttttggta
     4321 aggctaaggc aggtctttct gtatttacaa taaaaagtaa atctaaagtt gttccagtat
     4381 caataatatc taaatataaa ctttttagta aagtaattgt atatattgga gaaccaatat
     4441 catttgaaga acattttaag gaaaaattga gtaatgatga ccatgaaagg atatcacaag
     4501 agattttaga agtgataaaa caaaattact ttaaatattc aaaataaggg ggtaaagtta
     4561 tgaacataaa aatagcaaaa aatgctggct tttgttttgg agtaaaaaga gcaatgaaaa
     4621 tggcatggga tgaagttgaa aaaaatgatt ctggcatata tgctttaggt cctcttattc
     4681 ataacaagca agcagtagca aaatatgaag aaaaaggtct taagactgtg aatgaaattg
     4741 atacaatacc aaatcatgaa aatatgataa taaggtctca tggagttcct gaaaatatat
     4801 ataaggaagc caaagataaa aaattaaaaa ttgtggatac tacatgtcca tttgtaaaga
     4861 aaatacatac agtagtaagt gaatatcata ataaaggcta tgaaataata gttattggag
     4921 atatgaagca tccagaagtt ataggtataa atggatggtg tgaaaattca gctataataa
     4981 taaagacctt agaacaaatg gaaaatatgg aatttgataa ctccaaaaga tattgtcttg
     5041 ttgcacagac tacaataaat ccagagttgt atataagtat agttaataaa ctatcagata
     5101 aattagaaga aatagtattt aatgatacaa tttgttcagc tacaaaaaca agacaagaat
     5161 cagctaaaga gttagctaaa aaagttgatt gtatgatagt tataggaggt aaacacagtt
     5221 caaatactca aaagttagta aaggtttgtg aagacttagt accaactttt gcaatagaga
     5281 ctaaagatga attggatgta aatacgctta aaaaatataa aaatttgggt attacagcag
     5341 gggcatctac acctaattgg ataatagaag aagttgtaac attccttgaa aatttataat
     5401 ttgataggta ataaaaatag gtggacattg ttataattta tcataatatc cacctttgat
     5461 ttcatattac atgtggtaaa tagataacct aatatcaaaa agtgtgtatc ttaagatgaa
     5521 aaactaagag tataagatgc gcacttttta atattagaaa ttcaaaagaa atattgatat
     5581 tgattatcaa tagaaaatag aatataatat aattgttgca aaattagtct aggaggtaaa
     5641 ttaatggaaa tgttgatatc cgcttctgaa gaggcgtttt tacatgtagg ttctatgatt
     5701 ggatttttta ttttgttatt tggatatatt aattataaaa ctagtggaaa ttttactaat
     5761 atcatatcaa aaaacagaaa atttcaaccc ttaataggtg ctttaattgg agctatacca
     5821 ggttgtggcg gaagtttggc aataatgcca ttgtatataa atggaaaatt aagctttgga
     5881 gcaataattg caagtttaat agctagtatg ggagatgcag catttgtact tatttcatca
     5941 aatattaaaa tgtatttttt tgtcactata gttagtacaa ttacaggaat aataactgga
     6001 caattagtgg attactttaa actagaagaa aaattagggt taaaaaaccg tagaaaatca
     6061 gataaatatg atataagtaa aaataaccct aaagaaaata aagaacaaca taatcatgat
     6121 gaaataattt tagacactct agctaaatct catggaaata caaatagact tgcatttata
     6181 ataacacatg gaaagggata taaaatttat ataggaatta tagtaatcgg ttttatattt
     6241 atgtcacttg ctcactctgg acttaatctt cctataattg agaagttaca ttcattggaa
     6301 gaagtaatag cagtgattgg aatattattt tcaataattt atatgtggtg ttttaaaaag
     6361 gtatttaaaa attctaatca aaaagaggaa gaaaataaaa agatttcttt gcgagaaatg
     6421 cttatccatt ctgttggaga aatatcattt gtaattacat ggatttttat tgcatatctt
     6481 atttacgatt tgataatatt aattttaggt ggagatgaat acttagttaa attagtatta
     6541 tcaacaggtg taataagtgt atttataggt gcaggtcttg gacttattcc aggttgtggg
     6601 atacaaattg tgcttatgtc attttatttg aagggaacta taccacttgg tgcagtgata
     6661 gccaactcta tttctcaaga tggagatgca cttttcccac ttttagcaat ggataaaaaa
     6721 tcttctttat gggctatgat tattactact ataccagcaa tacttgtagg tatgatagtt
     6781 tatgcatttt taggttaaat ataattatga ataaagaagt attaaaaaaa taataaagca
     6841 cataaattta tttataagaa tagtgaagat taaatataaa aataaaaaat tcaatatgaa
     6901 ttaaattatt gcttaaatat taatgagaac atgggagata atattattcc tcatgttctc
     6961 tctatttaat taaaggaatt atggaacaaa tttcaagtga tactttctat caaaactcat
     7021 atataatata tattaataaa ttaaactata atacgtaata cagtcagtat attgatataa
     7081 aaaacttagg aggagttgta aaaatgggta atttaaaaag acagtgtgat gtttcaagtg
     7141 gaagagaaaa agctgacatt gtactaaaaa atgggacaat cataaatgta tttacagaag
     7201 agttaataac aggagatgta gcaatagtag gagacactat cgttggaatt ggcgattaca
     7261 agggcaatgt agaaattgat taaaaaatag ctacgcacac tcgtgacttt agtcatgagt
     7321 tagtagctaa aatagtcagc atatagggaa acctatatgt agagatagga tagaacctat
     7381 ccaatactac ttgaattgct ggaaacccct aaagctaatc aaactaaaac ataaggatga
     7441 aataaaccta agtgtgaaag ttacgaaagt agaaaaaatt ggttagatgg tataaggtta
     7501 aaccctaagt actttaaaat gggcaatcag caggtaaact ccgaatagga gaaacttcaa
     7561 cgactattcc tcttgaggga agtacactac aagctattgg tagtggaagt gggtagacct
     7621 taacggataa tgctgaagga taagatatag tctgtgcttg catgaaagtg taagaagttc
     7681 ataagagaac tgcataggta gtagcgaact tatgtgaacg acaacctcaa aaatgataaa
     7741 agttaagact tacggttctt aaatatgtta tttaaaatta aatataaaac cttctaaata
     7801 attgttttaa ataattacat ttgttaacat tattataggt gattaataaa ttgttcacca
     7861 cagcattata taatatatta aatatgataa aatcattaaa aagtgtatca aaaaacaatt
     7921 aaagtgaggt gatagtagtg gaaaaagctt ataagtttag aatgtatcca aataaaaaac
     7981 agcaagagtt aattaacaaa acttttggat gttgtagatt tgtgtataat aagtatcttg
     8041 ctaaaagaat agatgtttat aaaaaacata aagaaacttt tacttataaa cagtgtagtt
     8101 ctgatttgac caatttaaaa aaagaattaa agtggcttaa agaacctgac aaattttcac
     8161 tacaaaacgc cttaagagat ttagataatg catataaaaa attctttaaa gaaa
//
LOCUS       DAEPHU010000118         8129 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 01A10CD0081
            SAMN05941466-rid12468953.denovo.119, whole genome shotgun sequence.
ACCESSION   DAEPHU010000118 DAEPHU010000000
VERSION     DAEPHU010000118.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941466
            Sequence Read Archive: SRR6291087
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 8129)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8129)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068158.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 22:43:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,892
            CDSs (total)                      :: 3,805
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 87
            rRNAs                             :: 8, 1, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 55
            CDSs (without protein)            :: 55
            Pseudo Genes (ambiguous residues) :: 0 of 55
            Pseudo Genes (frameshifted)       :: 21 of 55
            Pseudo Genes (incomplete)         :: 28 of 55
            Pseudo Genes (internal stop)      :: 16 of 55
            Pseudo Genes (multiple problems)  :: 8 of 55
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8129
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941466-rid12468953.denovo.119"
                     /strain="01A10CD0081"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            116..883
                     /locus_tag="KR231_003517"
     CDS             116..883
                     /locus_tag="KR231_003517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424252.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YoaP domain-containing protein"
                     /protein_id="HBH0005844.1"
                     /translation="MQIIDININNIDNEHICCSISEKKGENCVFSKKAWMKNNFDKGL
                     VFKRFDVRGKAFIEYIPAENAWCPITADNYIFINCFWISGKFKGQGYSNLLLQECVDD
                     AKSKGKYGLVVLSSSKKMPFLSDAKYLKYKDFCLADTSEPNYELLYFPFTDNAPIPCF
                     KNCVKQRKLNENGIVLYYSNQCPHTEKYAPILKKIANSRGIDVNLIKFETAKEAQNAP
                     APFTTYSLFFNGEFVTNEILSEKKIEKFLDTNIKKFN"
     misc_binding    1101..1314
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            1568..2602
                     /locus_tag="KR231_003518"
     CDS             1568..2602
                     /locus_tag="KR231_003518"
                     /EC_number="1.2.1.38"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyl-gamma-glutamyl-phosphate reductase"
                     /protein_id="HBH0005845.1"
                     /translation="MNKIKVGIIGATGYVGAELIRLLMNHDKVEVTAIGSNSYVGKDI
                     VDIYPSIGYKNNMICIENEKVIDMCDVVFTALPHGVSEKFVIKAIKSKKKVIDLGADF
                     RIKDEEVYSKWYGVSFIDKILHKKAVYGLSEIYKEDIKDADIIANPGCYPTSISLPLM
                     PLLSSKLIKNNNIIIDSKSGLTGAGRELSISSHFTEVNENITAYKIGKHRHTPEIEQN
                     LSESCKEKVSVVFTPNLIPVNRGILSTIYCTKEDNISINDIHRKLTDYYEFKEFIEIL
                     PLDKIASLKNVRFSNKCVISLHENGDTLIICSAIDNMIKGAAGQAIQNMNIIFGIEEN
                     TGLKNIAPSF"
     gene            2643..3860
                     /gene="argJ"
                     /locus_tag="KR231_003519"
     CDS             2643..3860
                     /gene="argJ"
                     /locus_tag="KR231_003519"
                     /EC_number="2.3.1.1"
                     /EC_number="2.3.1.35"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional glutamate
                     N-acetyltransferase/amino-acid acetyltransferase ArgJ"
                     /protein_id="HBH0005846.1"
                     /translation="MEIIKGGVTVSEGFFASGIHCGLRKNKEKRDLALVYSDVLCDAA
                     AVVTQNKVKGNPVYVTQEHIKNGKAQAIIVNSANANTFNGKEGLINAYKMAKFTSDKL
                     NIKESDVLVASTGVIGKPLNIDLIEENMDELVNNLSKQGHIGAREAIMTTDIIKKEIA
                     VAIMYGDKKITIGGMAKGSGMIHPNMATTLGFITTDANIDGVLLKEALKIAVDKSFNR
                     VSVDGDTSTNDMVMILANGKAKNDRINKKDEHYQVFLSALTYVCIELAKLVAKDGEGC
                     TKLIECYINGALSEAHAVKLAKTVISSSLVKTAVFGADANWGRILCALGYAGEEIDME
                     KVDIIFESMKGYIEVCKNGNGLDFNEEKAKKILEDDEISILVDLNMGNARGNAWGCDL
                     SYDYVRINGSYRN"
     gene            3875..4735
                     /gene="argB"
                     /locus_tag="KR231_003520"
     CDS             3875..4735
                     /gene="argB"
                     /locus_tag="KR231_003520"
                     /EC_number="2.7.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetylglutamate kinase"
                     /protein_id="HBH0005847.1"
                     /translation="MINIEKANTLIEALPYIEKHQGKTIVVKYGGSAMKKDGLKESVM
                     EDLVLMSYVGINIVLVHGGGAEINKMLAKVDIESKFVNGLRYTDEETMEIVKMVLAGK
                     VNKDLVNKIHTKGGKAVGLCGIDNNMILCDPYKNYELGFVGEIKKVNVELIESCLKSG
                     YISVIATIGVGDDGETYNINGDTAASAIAKELNADKLILLTDVPGLLREPDEEKSLIT
                     EVILEDVDKLFEEGIITGGMIPKIEGCVDALNNGVNRVHILDGRVPHSIITELFTDSG
                     IGTLIRKENE"
     gene            4765..5952
                     /locus_tag="KR231_003521"
     CDS             4765..5952
                     /locus_tag="KR231_003521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate aminotransferase family protein"
                     /protein_id="HBH0005848.1"
                     /translation="MNNDNTISKWNEYFIDTYNQPNFVIDYGEGSCFFDTNGNKYIDF
                     TSGYGVSSLGYSNSNLKNALKEQVDKLLHTSNLYFNEPVLYSGEKIINSSGMAKVYFC
                     NSGTEANETAFKIARKYSSDKYGNGRGTIISLKDSFHGRTMMSLMATGMDKYHKYFYP
                     LPEGFKYVERNNIEDLKNNLDSTVCAIILEAIQGEGGVNVLEKDYVLEIVKICQEKDI
                     VVIFDEVQCGIGRTGKLFGYEYFDVKPDIVTVAKGLGAGIPVGGVLVNKKLSKVLGKG
                     DQGTTFGGNLLAMVAASVVLDEISKDGFYNEVLEKGNYIRKSIESFNNKVVLKTKGIG
                     LMIGIETNIESSIIEEKARKKGLLILTAGKNVLRFLPPLTISYKEIDEALEILKDILL
                     EIN"
     gene            6061..7083
                     /gene="argF"
                     /locus_tag="KR231_003522"
     CDS             6061..7083
                     /gene="argF"
                     /locus_tag="KR231_003522"
                     /EC_number="2.1.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine carbamoyltransferase"
                     /protein_id="HBH0005849.1"
                     /translation="MNNISLKGKSFLTLKDFTKEEIRYLLTLSSYLKTKKKVGIKGDL
                     LQGKNIALLFEKTSTRTRCSFEVAAHDEGAHVTYLGPNDCHMGKKESVSDTAKVLGRF
                     YDGIEFRGFKQETVESLAKYSGVPVWNGLTDEYHPTQILADFLTVIENVDKDLNKVKF
                     VYVGDARNNMGNSLMIGCAKMGIHFVALAPKELWPNEELVKEMKEIAKKSKGDIMLTE
                     NIDDVKGADVIYTDVWVSMGEEEQYEARINQLKDYQVNMDMIKKTENENVIFLHCLPA
                     FHDLETKVAQEIYEKFGLSELEVTNEVFNSKYSKVFEEAENRMHTIKAVMVSTMTDVN
                     MNNNLI"
     gene            7210..7827
                     /locus_tag="KR231_003523"
     CDS             7210..7827
                     /locus_tag="KR231_003523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435178.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4878 domain-containing protein"
                     /protein_id="HBH0005850.1"
                     /translation="MKKIILALTTFLLAISLTACSSAKPEDTIDSFFNSAKKFDFEGM
                     NKVMENNDEKYKDILKELDTKDPNAQYVLDYLKQNASKITYTIKDSEVKGDKATIKVE
                     CKFIDSTPLLQEIVAEAFTKMIGMSFSGQDLTDEKTTEMLVSIMKEKQKSVKETYVTK
                     NVEFECSKKDNKWIISSVNDAVADVLLSNLVTAGQEFSNSMNTLE"
BASE COUNT         3307 a          765 c         1506 g         2551 t
ORIGIN      
        1 aatattatgt aaaataaaaa tatatatgac atgatgttgt tgtattcaaa atattaagat
       61 aaaaatatat agaatatatt taaaaattat tatgcaatta gaaaaggaga taagtatgca
      121 gattattgat ataaatataa ataatattga caatgaacat atatgttgtt caatttctga
      181 aaaaaaagga gaaaattgtg ttttttctaa aaaagcttgg atgaaaaata attttgataa
      241 aggtctagtc tttaaacgat ttgatgtaag aggtaaagct tttatagaat atattccagc
      301 agaaaatgca tggtgtccta ttactgcgga caattatata tttattaact gtttttggat
      361 atctggaaaa tttaagggtc aaggatattc taatctattg ctacaagagt gtgttgatga
      421 tgcaaaatca aaaggtaaat atggattagt tgtgctttcg tctagtaaaa aaatgccttt
      481 tttatctgat gctaaatatc taaaatataa ggacttttgt ttagcagata catcagaacc
      541 aaattatgag ctattatatt ttccctttac tgataatgct cctattccat gttttaagaa
      601 ttgtgtaaaa caaagaaaat taaatgagaa tggtatagtt ttatattaca gtaatcagtg
      661 tccacatacg gaaaaatatg ctcctatttt gaaaaaaatt gcaaattcta gaggtattga
      721 tgtaaatctt ataaaattcg aaacagcaaa agaagcacaa aatgctcctg caccatttac
      781 tacatacagt ctttttttta atggtgaatt tgtaaccaac gagatacttt ctgagaaaaa
      841 gattgagaaa tttttagata ccaacattaa aaaatttaat taaaaagaga tgtaaatatt
      901 gtattttgaa aatatattat tttataattt aatatatttt ggatgttttt taaattgacg
      961 aatgaaatat aaaaattata tcgcaattta gatacaaaat gctggaaatt aaccatatag
     1021 aaaatatttc caaaaattta aaaattatat tgacaaagtt aaaaaaataa actatcatat
     1081 aaaacaataa gaaaataaat tgaaatcctg tgaaaaagag agtagcataa agctagttga
     1141 tagagagctg ggaatggtgg aagcctagta acgaatttta ttgtgaatag agctttggag
     1201 gagattacca gaagtaatag tatggtaatt ggtgaatctc gccttaagag attagagtgg
     1261 gtaagattat cttatcaatt agagtggtaa cgcgggtgta tattcgtctc ttggtctttg
     1321 accaagaggc ttttttaatt ttaaatgtac attttgtaga tactttttaa tttgagtttt
     1381 aatgattatt gtaattttac caataagagt ggtaccgcgg aaaatcgcct cttagtattt
     1441 ataatgctaa ggggtttttt gttttaatta gagtatttta atctacgtat tatcaaatga
     1501 ttatcatata gtaaagtgga aagataggat tttaagacta tttgaatata aaaatggagg
     1561 gaacaaaatg aataaaataa aagttggtat tattggtgca actggatatg tcggggcaga
     1621 gttgattaga ttattaatga atcatgataa agtcgaagtg acagcgatag gttcaaattc
     1681 gtatgttgga aaagatatag ttgatatata tccaagtata ggatataaaa ataacatgat
     1741 atgtatagaa aatgaaaaag ttatagatat gtgtgatgtt gtgtttacag cccttccaca
     1801 tggagttagt gaaaagtttg taataaaggc aattaaatcg aaaaagaaag ttatagattt
     1861 aggtgctgac tttagaataa aagatgaaga agtatatagt aaatggtatg gagtatcttt
     1921 tatagataaa atcttacata aaaaagctgt atatggatta agtgaaatat acaaagaaga
     1981 tataaaagat gcagatataa ttgcaaatcc tggatgttat ccaactagta tttctttacc
     2041 attgatgcca ttactaagtt ctaaattgat aaaaaataat aatataataa ttgattctaa
     2101 atcaggtctt acaggtgctg gtagagaatt atcgattagt agtcacttta cggaggttaa
     2161 tgaaaatatc actgcatata aaatagggaa acacagacat actccagaaa tagaacaaaa
     2221 tttaagtgaa tcctgcaaag aaaaagtaag tgtagttttt acaccaaact taatcccagt
     2281 aaatagggga atcttatcaa ctatatattg tacaaaagaa gataatattt ctataaatga
     2341 tatacatagg aaattaactg attattatga atttaaagaa tttatagaaa ttcttccatt
     2401 agataagata gcttctttaa agaatgttag attctcaaat aaatgtgtaa tatcattaca
     2461 tgaaaatgga gatacattga taatctgttc agctatagat aatatgatta agggagcagc
     2521 aggtcaagct atacaaaaca tgaatataat atttggtatt gaagaaaata caggtttaaa
     2581 aaatattgca ccatcatttt agaaataaaa aatactaaac tcatataatt aggaggataa
     2641 atatggagat tataaagggt ggagttacag tttcagaagg attttttgct tcagggattc
     2701 actgtggctt gagaaaaaat aaagaaaaaa gagatttagc tttggtttat tcagatgttt
     2761 tatgtgatgc agcagcagta gtaactcaaa ataaagtaaa gggcaatcct gtttatgtta
     2821 cacaggaaca cattaaaaat ggaaaagcac aagctatcat agtaaatagt gctaatgcta
     2881 atacctttaa tggaaaagaa ggacttataa atgcttataa aatggctaaa ttcaccagtg
     2941 ataaattaaa tattaaagaa agtgatgttt tggttgcatc tacaggtgtt ataggaaagc
     3001 cattaaatat agatttaata gaagaaaata tggatgaatt agtgaataat ctaagtaaac
     3061 aaggtcatat tggagcaaga gaagctatta tgacaactga tattataaaa aaagaaatag
     3121 cagtagcaat aatgtatgga gataaaaaaa taactattgg aggtatggca aaaggttctg
     3181 gtatgataca tcctaatatg gcaacaacgt taggatttat aactacagat gcaaatattg
     3241 atggagtttt gctaaaagaa gctttaaaaa ttgctgttga caaaagtttt aatagagtta
     3301 gtgtagatgg agatacaagt actaatgata tggtaatgat tctagcaaat ggaaaagcaa
     3361 aaaatgatag aataaacaaa aaagatgaac attatcaagt atttttgagt gcacttacat
     3421 atgtctgtat agaacttgct aaacttgttg caaaagatgg agaaggatgt acaaaactaa
     3481 ttgaatgcta tataaatgga gcattaagtg aagcacatgc agtaaaatta gcaaaaacag
     3541 ttatatcttc ttcattagta aagacagctg tatttggagc tgacgcaaat tggggtagaa
     3601 tactgtgtgc tttaggttat gcaggtgaag aaatagatat ggaaaaagtt gatattattt
     3661 ttgagagtat gaaaggatat attgaagtat gtaaaaatgg aaatggatta gattttaatg
     3721 aggaaaaagc aaaaaaaatc cttgaagatg acgaaataag tatattagta gatttaaata
     3781 tgggcaatgc cagaggaaat gcatggggat gtgatttaag ctatgattat gtaagaataa
     3841 atggaagtta tagaaattag gaggatatac tttaatgatt aatatagaaa aagcaaatac
     3901 acttatagaa gctttaccat atatagaaaa acatcaggga aagactattg tagttaagta
     3961 tggtggaagt gcaatgaaaa aagatggtct aaaagaatct gttatggaag accttgtgtt
     4021 aatgagttat gttggaatca atatagtttt agtacatggt ggaggggcag aaatcaataa
     4081 gatgctagca aaagtggata tagaaagtaa atttgtaaat ggtcttagat atacagatga
     4141 agagaccatg gaaattgtaa aaatggtact tgctggaaag gttaataaag acctagtaaa
     4201 taaaatacat acaaaaggtg gaaaagcagt agggctttgt ggaatagata ataatatgat
     4261 tttatgtgac ccatataaaa attatgaact tggatttgta ggagaaatca aaaaagtaaa
     4321 tgttgagctt atagaatctt gtctaaagtc aggttatatt tcagtaattg caactatagg
     4381 tgttggagat gatggagaga cttataatat aaatggtgac acagcagctt ctgctatagc
     4441 taaagagtta aatgcagata aattgatact tcttacagat gtccctggtt tgttaagaga
     4501 gccagatgaa gaaaaatcat taataacaga agttatatta gaggatgttg ataaattatt
     4561 tgaagaaggt ataattactg gaggtatgat acctaaaata gagggatgcg tagatgcctt
     4621 aaataacgga gtaaataggg tacatatttt ggatggaaga gttccacatt ctataataac
     4681 agagctattt actgatagtg gaataggtac attaataaga aaagaaaatg aataaaatta
     4741 taagtttaag aggggagaat aagaatgaat aacgacaata caatttcaaa atggaatgaa
     4801 tattttatag atacatataa tcaacccaat tttgtcatag attatggtga aggaagttgt
     4861 ttttttgata ctaatggcaa taaatatata gattttacaa gtggatatgg agtatcttct
     4921 cttgggtata gtaatagtaa tttaaagaat gctctaaaag agcaagtaga taaattatta
     4981 catacttcaa atttatattt taatgagcca gtgttgtatt caggagagaa aataattaat
     5041 tcaagtggaa tggctaaagt atatttttgt aattctggaa cagaagcaaa tgaaacagca
     5101 ttcaaaatag caagaaagta tagtagtgac aaatatggta atggtagagg aactatcata
     5161 agtttaaaag actcttttca tggtagaaca atgatgtctt taatggcaac tggtatggac
     5221 aaataccata agtattttta tcctcttccc gaaggtttta aatatgtaga aagaaataat
     5281 attgaagatt taaaaaataa tcttgattcc acagtttgtg caataattct tgaagcgatt
     5341 caaggcgaag gtggagttaa tgttcttgaa aaagattatg ttttggaaat agtaaaaata
     5401 tgtcaagaaa aggatattgt agtgattttt gatgaagtcc aatgcggtat aggaagaact
     5461 ggtaaacttt ttggctatga atattttgat gtaaaaccag atatagttac cgtagcaaaa
     5521 gggttgggag caggaatacc agtaggagga gtattagtaa ataaaaaact ttcaaaagta
     5581 ctaggaaaag gagaccaagg tacaactttt ggaggtaatt tattagctat ggtggcagct
     5641 tcagttgtat tagatgagat atctaaagat ggtttttata atgaagtatt agaaaaagga
     5701 aattatataa gaaaatctat tgaaagtttt aataacaaag ttgtattaaa gacaaaaggt
     5761 attggtctaa tgataggaat tgaaactaat attgaatcta gtattataga agagaaagct
     5821 agaaaaaaag gattgcttat tttgactgct ggaaaaaatg tattgagatt tttaccacca
     5881 ttaacaatca gttataagga aatagatgag gctcttgaaa tcctaaaaga tatattacta
     5941 gaaattaact aaatattcaa gaaatagttg attaaagata aaaattagaa gtaaataaaa
     6001 aagtaaagtg ctaacaagtt taattgaatt taaaaagttt ataagaaggg gcgaattaat
     6061 atgaataata taagtttaaa aggtaagagt tttttgacat taaaggattt tacaaaagaa
     6121 gagattagat atttattaac tttatcaagt tatttaaaaa ctaagaaaaa agttggtata
     6181 aaaggcgatt tgctacaagg aaaaaatata gctttattat ttgagaaaac atcaacaaga
     6241 actagatgtt catttgaagt agcagctcat gatgaaggag cacatgtaac ttatctaggt
     6301 ccaaatgatt gtcatatggg taaaaaagag tctgtatcag atacagcaaa agttctagga
     6361 agattctatg atggaataga atttagaggc tttaaacaag aaacagttga aagtctagca
     6421 aaatattctg gtgtgcctgt ttggaatgga cttacagatg aatatcatcc aacacaaata
     6481 ctggcagatt ttttaacagt aattgaaaat gtagataaag atttgaataa agttaaattt
     6541 gtatatgttg gtgatgctag aaataatatg ggaaactcac tgatgatagg atgtgctaaa
     6601 atgggaatac atttcgtagc actagcacct aaggaacttt ggccaaatga agaattggtt
     6661 aaggaaatga aggaaatagc caagaaatcc aaaggagata taatgttgac tgaaaatatt
     6721 gatgatgtta aaggtgcaga tgttatatat acagatgtat gggtttctat gggagaagag
     6781 gagcaatatg aagcaagaat aaatcaactt aaagattatc aagtaaatat ggatatgata
     6841 aagaaaactg aaaatgaaaa tgttatattt ttacactgtc ttccagcatt tcatgattta
     6901 gaaactaagg ttgctcagga gatttatgaa aagttcggat tatcagaatt agaggttaca
     6961 aacgaggtat ttaattcaaa atattcaaag gtatttgaag aagctgaaaa tagaatgcat
     7021 acaataaaag ctgttatggt ttctactatg actgatgtaa atatgaacaa taatttaata
     7081 tagatatgtt ttaatataga ctttacttta atgaaaattt ataaaatatt ttaaatatat
     7141 tattcaaaaa ctctcattat atgttaaaat aacttatgta tcaacaaatt aagagggagg
     7201 atttgagata tgaaaaaaat catattagct ttaacaactt ttttattagc aatatcttta
     7261 acagcatgtt caagtgcaaa accagaagat acaattgata gtttttttaa cagtgcgaaa
     7321 aagtttgact ttgaaggcat gaataaggta atggaaaata atgacgaaaa atataaggat
     7381 atattaaagg aattagatac aaaagaccca aatgcccaat atgttttaga ttatctaaaa
     7441 cagaatgcat ctaaaatcac atatacaata aaagacagcg aggttaaagg tgataaggct
     7501 acaatcaaag tagaatgtaa atttatagat tcaacaccat tacttcaaga aatagtagct
     7561 gaggcattta caaagatgat tggtatgagt ttttcaggac aagacttaac tgatgagaaa
     7621 acaactgaaa tgttagtatc aattatgaaa gaaaaacaaa aaagcgttaa agagacttat
     7681 gttacaaaaa atgtagagtt tgaatgttct aaaaaggata ataaatggat aataagttca
     7741 gtaaatgatg cagtagctga tgtattgtta tctaatcttg ttacagcagg acaagaattt
     7801 tctaactcta tgaatacact tgaataatat tgtttaggtg tagtaaagta ataaatatat
     7861 gattattttt ataaataaac atataaatat ttatgaagga taccattttt ggtatccttt
     7921 ttattaatat aatgaaatac atggttaatt tctatattgt caagaaacta tgatatatgt
     7981 tataagtcta tactatttaa aataaactta taacatatat tttttataat atagtgcatg
     8041 aaaaatttat ttaactaatt ttagatattt attgacaact gattcagcca agcattttga
     8101 tgaatcaaca atatttattg aaggatatg
//
LOCUS       DAEPHU010000119         8057 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 01A10CD0081
            SAMN05941466-rid12468953.denovo.120, whole genome shotgun sequence.
ACCESSION   DAEPHU010000119 DAEPHU010000000
VERSION     DAEPHU010000119.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941466
            Sequence Read Archive: SRR6291087
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 8057)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8057)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068158.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 22:43:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,892
            CDSs (total)                      :: 3,805
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 87
            rRNAs                             :: 8, 1, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 55
            CDSs (without protein)            :: 55
            Pseudo Genes (ambiguous residues) :: 0 of 55
            Pseudo Genes (frameshifted)       :: 21 of 55
            Pseudo Genes (incomplete)         :: 28 of 55
            Pseudo Genes (internal stop)      :: 16 of 55
            Pseudo Genes (multiple problems)  :: 8 of 55
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8057
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941466-rid12468953.denovo.120"
                     /strain="01A10CD0081"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            288..692
                     /locus_tag="KR231_003524"
     CDS             288..692
                     /locus_tag="KR231_003524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication/maintenance protein RepL"
                     /protein_id="HBH0005851.1"
                     /translation="MDKTLKKDLNQEYTESKSLVMNKSKYMNVCFKNYIKVVEGMYTK
                     RDLIPLKLINSMDKNNKIRKTLYELSCEFEYPKTSLSSLFTELKKMDFLQRVKNGEYM
                     INPHIAYKGSRADKESLLAEYNQIKRPNKVSK"
     gene            709..1305
                     /locus_tag="KR231_003525"
     CDS             709..1305
                     /locus_tag="KR231_003525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0005852.1"
                     /translation="MSLKLDRNVLQWFDYVFENEKTSLRHYNFNCTLKEISSTSLNKV
                     AFILEKNNSKYWKLYFEIPAEVTLKLKQNIHPLFREYIYEQISLYNNNQIYNFVNSNI
                     LKVFNNIAIYQYNILENLYTIDFKKSFIDKCQYLLIGEKRLIDEDLYLIAKSKEVFDF
                     FNSDGTFNLTLSFDIQKNENLLDSLLELRKSIIINERI"
     gene            1342..3936
                     /gene="clpB"
                     /locus_tag="KR231_003526"
     CDS             1342..3936
                     /gene="clpB"
                     /locus_tag="KR231_003526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent chaperone ClpB"
                     /protein_id="HBH0005853.1"
                     /translation="MDVEKMTLRVQKSLNEAYNEAVKNHNQQVDVIHLFSALINQEDG
                     LIPNIIEKMNISIDSLRNTVNFEIDKLPKVYGEGADSQGVSATRKINEVLIKAESISK
                     EFKDSYISVEHVMLAMMETESKSAVGKILKQYNINKNDFLNILSQVRGSQRVETQDPE
                     GTYDALARYGTNLVDLAKKNKLDPVIGRDEEIRRIIRILSRRTKNNPVLIGEPGVGKT
                     AIVEGLAERIVRGDVPEGLKDKIVFSLDMGALIAGAKYRGEFEERLKAVLKEVQSSDG
                     KIILFIDEIHTIVGAGKTEGSMDAGNLIKPMLARGELNCIGATTFDEYRKYIEKDKAL
                     ERRFQPVIAEEPTVEDTISILRGLKERFEIHHGVRIHDNAIVAAAKLSHRYIQDRFLP
                     DKAIDLIDEAGAMIRSEIDSLPTELDVVRRKLFTLETEREALLKENDDKSKSRLDDIQ
                     KEIAELKSKNDEMTAKYEKEKSQILDIKNLKAQLDEAKGKAEKYEREYDFNKAAEVKY
                     GEIPKLEEQIKQYEENMNDGSENSLLKEEVTEEEISSIVSKWTGIPVTKLVEGEREKL
                     LKLEDELHKRVIGQDEAVTAVSNAVIRARAGLKDERKPIGSFIFLGPTGVGKTELAKT
                     LARNLFDSEDNIIRIDMSEYMEKHAVSRLVGPPPGYVGYEEGGQLTEAVRRAPYSVIL
                     FDEIEKAHEDVFNMFLQILDDGRLTDNKGKTVDFKNTLIIMTSNIGSNYLLEAGGNIT
                     ETTNNLVMNEMKHRFKPEFLNRVDDIIMFKPLDQENIKKIIDIFMKDLKNRLKEKDIT
                     IEVTNSAKDVMVREGYDPVYGARPLKRYIGNTLETIIAKKLIAGDVYNGCTIVIDGKD
                     ENIEVLVK"
     gene            complement(4132..5559)
                     /locus_tag="KR231_003527"
     CDS             complement(4132..5559)
                     /locus_tag="KR231_003527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBH0005854.1"
                     /translation="MTNSFKKDDNRKKITVLFVVIAMTFMATLDSSIINVALPVLASK
                     LNVSLASIEWVIASYSIIICSTLLFFGRLGDIIAKSRVFQVGTILFTSASLLCGLSNS
                     LTLLIVCRFIQGIGASAYMANNHGIITELFPKESRGKALGILVTAVAIGNMVGPSVGG
                     FILSIFNWNVIFFINIPIGLIVIFLNTKFLPNSKKSSENMDKTGAILQFLGTTLFFSA
                     LISAQQTGLLNPYILIALLLSIIFIILFLILEKKHPQPLLDLEIFRNFKFSLNLICAL
                     TSFICIASSSILIPFYLQSTMKLPPIQAGLFMILSPLILAIFSPIFGNISDKIKSEKI
                     ILIGLLVMSFGFFLMSRLKESSALILFVIYISIISIGQAIFQPANNALIMSSCSRSKL
                     GVVGSINSLVRNLGQVIGITISTTLLYNFMSIKAGYRVNDYVINNDKIFVFGMRNVYI
                     IVTLVCLIGAILIGFYLFKYNKNEQ"
     gene            5700..6596
                     /locus_tag="KR231_003528"
     CDS             5700..6596
                     /locus_tag="KR231_003528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HBH0005855.1"
                     /translation="MKDKNTYFNRKGQENFIDIFLKDDIKKGANFKRHWHEHLQIYYF
                     IDGIAYLECGLDNFKVVPGNIVIANSNELHYLESLSDNLKFYSIRIEPTFLFSNQVDL
                     LQTKYLAPLALNHIVFNNLIQNDSLILKCITTILDEYHNKEVGYELSIKANIYQLIVL
                     LLRSHIDKIYSEDEFIKRKYSLEKFECIFDLIEEKYMDKITLKELASRVNLSAHHFCR
                     TFKQITGKTTIDFINGIRLDKAIYYLKETDLNMTEIAMRCGFDSINYFSRLFKKNYNI
                     SPTKYRNEHREVSNVILKEDMK"
     gene            7261..7401
                     /locus_tag="KR231_003529"
     CDS             7261..7401
                     /locus_tag="KR231_003529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0005856.1"
                     /translation="MEKSNTTVTKKEKIEDIGMKLEHLLSEDITFYELLLEILYKEKE
                     EN"
     gene            complement(7398..7769)
                     /locus_tag="KR231_003530"
     CDS             complement(7398..7769)
                     /locus_tag="KR231_003530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBH0005857.1"
                     /translation="MESLGDRIANLRKELDINQKELATKVGITEASLSRYENNLREPK
                     SEIIVRLAKALETSTDYLLGVNDNTKISKEDKLIIENLSVSEKTKKLLEKIYSLEKED
                     REAIEKMIDNAYLKRFLKEEN"
BASE COUNT         3327 a          834 c         1234 g         2662 t
ORIGIN      
        1 aaaactaatt gccaatatta tacatttaat aaatgtaatg tattttatga aagtctgcca
       61 tattaaatag atttaaattt ttttaaaaaa tttataaata ttgttcaaaa atcctgccaa
      121 taaattggaa atactaaatt aaaaaaataa taaagtttag cttatagcta aataaaagtt
      181 tacttataag gtgaactttt tgcattttca gttttgacat acatattttt ttgtaatata
      241 tttatattat caattagaga taaggagagt gagaagagat atttaatttg gataagacat
      301 taaaaaagga tttaaatcag gaatatacag agagcaaaag tttagttatg aataaaagta
      361 agtatatgaa tgtttgtttt aagaattata ttaaagtagt agaaggaatg tatactaaga
      421 gggatttaat tccattaaaa ttaataaact ctatggataa aaataataag attagaaaaa
      481 cattatatga attatcttgt gaatttgaat atccaaaaac ttctttatct tcattgttta
      541 cggagctgaa aaaaatggat tttttacaaa gagtgaaaaa tggtgagtat atgataaatc
      601 cacatatagc atataaaggt agtagagctg ataaagaaag tttattagca gaatataatc
      661 agataaaaag acctaataag gttagtaaat aaggaagaag gtttttatat gagtttaaaa
      721 cttgatagaa atgttctaca gtggtttgac tatgtatttg agaatgaaaa aactagtttg
      781 agacactata attttaattg tacactaaag gagattagtt ctaccagttt gaacaaagta
      841 gcttttattt tagaaaaaaa taactctaag tactggaagc tttattttga aataccagct
      901 gaagttactt taaaacttaa gcaaaacatt catcctttat ttagggaata tatatacgaa
      961 caaatatcac tgtataacaa taatcaaatt tacaattttg taaattcaaa catattaaaa
     1021 gtgtttaata atattgctat ttatcaatat aatattttag aaaatctata cactattgat
     1081 tttaaaaaga gttttataga taaatgtcag tatttattaa taggtgaaaa aagacttata
     1141 gatgaagact tgtatttaat agcaaaatca aaagaagtat tcgatttttt taattcagat
     1201 ggaacattta atttaacatt gagtttcgat atacaaaaaa acgagaattt acttgatagt
     1261 cttttagagc ttagaaaatc aataattata aatgagagaa tttaatttat ttggatataa
     1321 tattaaaatg gagggattta tatggacgta gaaaaaatga ctttaagagt tcaaaaaagt
     1381 ttaaatgagg cttataacga agcagtaaaa aatcataacc aacaagtaga tgtaattcat
     1441 cttttctcag cacttattaa tcaagaggat ggattgatac caaatataat cgaaaaaatg
     1501 aatatatcaa ttgattcttt gagaaatact gtaaactttg aaattgataa gcttccaaaa
     1561 gtatatggag aaggtgctga ctcacaagga gtatcagcta ctagaaaaat aaatgaggtg
     1621 cttataaagg cagagagtat ttctaaagaa tttaaagatt catatataag tgtagaacat
     1681 gttatgcttg caatgatgga aacagaatca aaatcagctg ttggtaaaat attaaaacaa
     1741 tataatataa ataagaatga ctttttaaat attttatcac aagtgagagg tagtcaaaga
     1801 gtagaaacac aagacccaga aggcacatat gatgcacttg ctagatatgg aacaaactta
     1861 gtagatttag ccaagaaaaa taaattagac cctgtaattg ggagagatga agaaataaga
     1921 aggattataa gaattttatc aagaagaaca aaaaataatc ctgtattgat tggtgagcca
     1981 ggtgtaggta aaactgcaat tgtagaaggg ttagcagaga gaatagtaag aggagatgtc
     2041 ccagaaggtt taaaagataa gattgtattc tcacttgata tgggagcttt aattgctggt
     2101 gcaaaatata gaggtgaatt tgaagaaaga ttaaaggcag ttttaaaaga agttcaaagt
     2161 tctgatggaa aaattatact gtttatagat gagattcata ctattgttgg agctggtaaa
     2221 acagaaggtt caatggatgc aggtaatctt attaaaccta tgcttgcaag aggtgaattg
     2281 aactgtattg gtgcaactac ttttgatgaa tatagaaagt atatagaaaa agataaggct
     2341 cttgaaagac gttttcagcc tgtaattgca gaagaaccta ctgttgaaga tacaatatct
     2401 atacttagag gtttaaaaga aagatttgaa atacatcatg gagtaagaat acatgataat
     2461 gctattgtag cagcagcaaa actttctcat agatatatac aagatagatt tttaccagat
     2521 aaagcaattg atttaattga tgaagctgga gctatgattc gtagtgaaat agattcattg
     2581 ccaacagaat tagatgttgt tagaagaaag ttatttacat tagaaactga aagagaagca
     2641 ttacttaaag aaaatgatga taaaagtaaa tcaagattgg atgatattca aaaagaaata
     2701 gcagagttaa aatctaaaaa tgatgaaatg acagcaaaat atgaaaaaga aaagagtcaa
     2761 atattagata ttaaaaactt aaaggctcaa ttagacgaag ctaaaggtaa agctgaaaag
     2821 tatgaaagag aatatgattt caacaaagca gcagaggtta aatatggtga aatacctaag
     2881 ttagaagaac aaataaagca gtacgaagaa aatatgaatg atggttctga aaattctctt
     2941 ttaaaagaag aagttactga agaagaaata tctagcattg tatcaaagtg gacaggtata
     3001 ccagtaacta aactagttga aggagaaaga gaaaaattac ttaaactaga agatgaactt
     3061 cataaaagag ttattggaca agatgaagca gttacagcag tttcaaatgc agtaatacgt
     3121 gcaagagcag gattaaaaga tgaaagaaaa ccaattggtt catttatttt cttaggccct
     3181 acaggtgttg gtaaaactga acttgcaaaa actcttgcta gaaatttatt cgatagtgaa
     3241 gataatataa taagaataga tatgtctgaa tacatggaaa aacatgctgt atcaagacta
     3301 gttggacctc ctccagggta cgtgggatat gaagagggtg gtcaacttac agaagcagtt
     3361 agacgtgctc cttattctgt aatactattt gatgagatag aaaaagcaca tgaggatgta
     3421 tttaacatgt tcttacagat attagatgat ggtagactta ctgataataa aggtaagaca
     3481 gtagacttta aaaatactct tataataatg acttctaata taggaagtaa ttatctatta
     3541 gaagcaggag gaaatataac agagactact aacaatttag taatgaatga aatgaagcat
     3601 agatttaaac ctgagttttt aaacagagta gatgatatta taatgtttaa gcctttagac
     3661 caagaaaata tcaagaaaat tatagatata tttatgaaag atttaaaaaa tagattaaaa
     3721 gaaaaagata ttactattga agttacaaat tcagcaaaag atgttatggt gagagaagga
     3781 tatgaccctg tatatggagc aagacctctt aagagatata taggaaatac attagaaact
     3841 ataattgcaa agaaacttat tgctggagat gtgtataatg gatgtactat agttatagat
     3901 ggaaaagatg aaaatattga agttttagtt aaataataaa agaatcagtt gagcataata
     3961 tactaaatat tttgctcagc tgatttttat ttataaacta taggaaaaga aatattttat
     4021 caaattaata aaacattttt aagtcaatat gtccaaatta aatttaactc aaaggaagta
     4081 ttttagtaaa tttcttataa tataatcata atttgaatat aattataaaa actattgttc
     4141 atttttatta tatttaaata aataaaagcc aattaatatt gcacctatta agcaaacaag
     4201 tgtaacaata atataaacat ttctcattcc aaatacaaat attttatcat tattaatcac
     4261 ataatcattg accctatatc cagctttaat actcataaaa ttatataaaa gtgttgtaga
     4321 aatagtaata cctataactt gtcctaaatt tcttacaagg gaatttatgc ttcctacaac
     4381 tcctagctta cttctagaac agcttgacat tatcaaagca ttgttagcag gttgaaatat
     4441 agcttgtcct attgatatta tcgatatata aattacaaat aaaataaggg cagaactttc
     4501 tttcaatctt gacattagaa agaatccaaa actcataacg agaagaccaa ttaaaataat
     4561 tttttctgac ttaattttat ctgatatatt cccaaatata ggtgaaaaaa tggctaaaat
     4621 caaaggtgat agtatcataa ataaacctgc ttgaataggg ggaagtttca tagtactttg
     4681 taaataaaat ggaattaaaa tacttgatga tgcaatacaa atgaatgatg taagagcaca
     4741 aattaaattc aatgaaaatt taaaatttct aaaaatttca aggtcaagaa gcggttgagg
     4801 atgttttttt tctaatatca aaaataatat aataaaaata attgataata atagtgcaat
     4861 taatatatat ggatttagta atcctgtttg ttgagcacta attagagcac taaaaaataa
     4921 tgttgttcct aaaaattgaa gtatagcacc agttttatcc atattttctg aagatttttt
     4981 actattagga agaaattttg tatttaaaaa gattacaata agaccgattg gaatatttat
     5041 aaaaaatata acattccaat taaatattga caaaataaat cctcccacag atggtccaac
     5101 catatttcca atagcaactg cagtaactaa aatccctagg gcttttcctc tgctttcttt
     5161 tggaaatagt tctgtgataa ttccatgatt gtttgccatg taggcagaag cgcctattcc
     5221 ttgaataaag cggcaaacta taagtaaagt taaagaatta cttaatccac atagtaatga
     5281 agctgatgta aagagaatag tacctacttg aaatactctt gatttagcaa taatatctcc
     5341 aagtcttcca aaaaataata gtgttgaaca aataataatt gagtaacttg ctattaccca
     5401 ttcaatagat gctagagata catttagttt gcttgcaaga actgggagag caacatttat
     5461 aatactagaa tctaatgttg ccataaaagt catggcaatg actacaaata aaactgtgat
     5521 tttttttcta ttatcatctt ttttaaaaga gtttgtcatt tttattacct ccttattata
     5581 atgactgcat tatgttaatg tttacaatga tagttacatt ttatataata gcgatatgaa
     5641 ataatgaata caataactat attgcttata attagcacta ttttgatgag gggggaataa
     5701 tgaaggataa aaatacatat tttaacagga aaggtcaaga aaactttata gatatttttt
     5761 taaaggatga cattaaaaaa ggagcaaact ttaaaagaca ttggcatgag catctacaaa
     5821 tatattattt tattgatggt atagcatatc ttgaatgtgg attggataat tttaaggtag
     5881 tgcctggaaa tattgtaata gcaaacagta atgaattaca ttatttagaa agcttatcag
     5941 ataatttaaa attctatagt attcgtattg aacccacatt cctttttagt aatcaagttg
     6001 atttgttaca aaccaagtac ttagcaccat tggctttaaa tcatattgta tttaataatt
     6061 taattcaaaa tgattctctg attttaaaat gtattacaac tatacttgat gaatatcaca
     6121 ataaagaagt tggatatgag ttatctataa aagctaatat ctatcaatta atagtactct
     6181 tattaagaag tcatattgat aaaatatatt ctgaagatga atttataaaa agaaagtatt
     6241 ctttagaaaa atttgaatgt atctttgatt tgatagaaga aaaatatatg gataaaatta
     6301 cattaaaaga acttgctagt cgtgtgaact tgagtgcaca tcacttttgt agaacattta
     6361 agcaaataac aggtaagact acaatcgatt ttataaatgg aatcaggctt gataaagcta
     6421 tatattattt aaaggaaaca gatttaaata tgacagaaat tgctatgaga tgtggctttg
     6481 atagcataaa ttattttagt cgcttattta aaaagaatta taatatatct ccaactaagt
     6541 atagaaatga acatagagaa gttagtaatg ttattttaaa agaagatatg aaataattca
     6601 taaatatact ttatagaaaa tatatatttt taaatctttg aatttttctt aataaatatt
     6661 aataaagcat aggatataaa tgagtaagac tacttgtata gttaaatgtg aaaatgagta
     6721 tgaaagaatg tagtgtctat gaaaagtata ttttaatatg aaactaaaat tggaaaaata
     6781 agaatagcag aaaaaatgat tatattataa atcagttttt ttgagacatc tggcttagat
     6841 tctgaaagat atttaatcaa agaaataaaa ctattaaata agcaagtaaa cagctaaaat
     6901 agtatgattt ttatagaaaa tttaaatcca tcctaaagaa ttaaaagaaa gtcaaataaa
     6961 tataaaaaaa ttatatattt ataaaaaatt ttataataaa aatcatcctg aaaaatatat
     7021 aaaaatagaa aaaacataca agattctaca ataatagatt tttttgttat tattacgagt
     7081 tttttattgc aactgtagaa taaaagtatt attatataat taagataatt atctagggaa
     7141 attttggata atcaaaatat attttataaa atcaaaatac aattacataa actttattaa
     7201 aaatttgttg ggaatttctg actaacatta agaacgtaag tttgttgggg gatggtatat
     7261 gtggaaaagt caaacactac tgttacaaaa aaagaaaaaa ttgaagatat aggaatgaaa
     7321 ttagaacatt tattgagtga agatattact ttttatgaat tattacttga gattttgtat
     7381 aaagaaaaag aagagaatta attctcttct ttaaggaatc tttttaaata ggcattatca
     7441 atcatttttt ctatagcttc tctatcttct ttttcaagag aatatatttt ttctaagagc
     7501 ttttttgttt tttcacttac tgataagttc tctatgatta atttatcttc tttgcttatt
     7561 tttgtattat catttacgcc taataaataa tctgttgatg tttctaatgc ttttgctaat
     7621 ctaactatta tttcactttt aggttctctt aaattatttt cataacgtga caagctagcc
     7681 tcagttatac cgactttagt agcaagttct ttttgattta tatctaattc ttttcgtaga
     7741 tttgctattc tatctcctaa actttccata tgtacatcac tccttaccga aattataagt
     7801 tattttgata aaaagtaaaa taaaattacc aaaaatataa aaaaaaaagg ttaaaataat
     7861 aaaatatatt gaaaattacc atttgtatat gtataatatg aattatacaa atggtaattt
     7921 gatgagaggt ggtatgttga aataagaaac tgaattaatt aataaataca tagaaagttt
     7981 tgaaaacctt taattgaaat ataaacaata tgtacaaaat tttttgcaag taaaattacc
     8041 aaatgtataa aataaat
//
LOCUS       DAEPHU010000120         7979 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 01A10CD0081
            SAMN05941466-rid12468953.denovo.121, whole genome shotgun sequence.
ACCESSION   DAEPHU010000120 DAEPHU010000000
VERSION     DAEPHU010000120.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941466
            Sequence Read Archive: SRR6291087
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 7979)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7979)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068158.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 22:43:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,892
            CDSs (total)                      :: 3,805
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 87
            rRNAs                             :: 8, 1, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 55
            CDSs (without protein)            :: 55
            Pseudo Genes (ambiguous residues) :: 0 of 55
            Pseudo Genes (frameshifted)       :: 21 of 55
            Pseudo Genes (incomplete)         :: 28 of 55
            Pseudo Genes (internal stop)      :: 16 of 55
            Pseudo Genes (multiple problems)  :: 8 of 55
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7979
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941466-rid12468953.denovo.121"
                     /strain="01A10CD0081"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            88..684
                     /locus_tag="KR231_003531"
     CDS             88..684
                     /locus_tag="KR231_003531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429797.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3298 domain-containing protein"
                     /protein_id="HBH0005858.1"
                     /translation="MNFKQDNYEVNVSIPKIKGLKDKTLENKLNNEFLQDGKKIYSEF
                     QNKMKKENNKGHRYLNVIHNVKNNSKDFLSIEMTKEEIEASSSITKKHYTVDKNRGIL
                     LNLPIFFKDSRYIRAISDNIKEQMRNQIKKDDTKSYFIDQDKDSPVKDFESINKYQDF
                     YFNKNGNLVISFDEYEVAPGYMGAVEFVIPNKVIKRLR"
     gene            726..1547
                     /locus_tag="KR231_003532"
     CDS             726..1547
                     /locus_tag="KR231_003532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xanthine dehydrogenase accessory factor"
                     /protein_id="HBH0005859.1"
                     /translation="MNIYEQAIRLIENNEDFAFATITSHSGSTPRETGAMMIVKNDST
                     IFGSVGGGSVEAECIKHAINVIKNRESMLYKFTLNKSDVAKLGMICGGTGEIQIDFID
                     SKLKSNIEKFNKRLKENTSKAYIFGAGHISRDVAVILSLLEFRTVVIDDREEFANHER
                     FPESEVVVLDSFENIPDFPTDENSYIIILTRGHLYDSSALEWALKREAGYIGMIGSRT
                     KIGLTYEKLMKKGFKKEELSKVHAPIGIKLNAQTPAEIAVCIAAELINCRANKEK"
     gene            1552..2313
                     /locus_tag="KR231_003533"
     CDS             1552..2313
                     /locus_tag="KR231_003533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M48 family metallopeptidase"
                     /protein_id="HBH0005860.1"
                     /translation="MNTGSKDIDTLKVNFRGIEIKAVLVYKNRKNISIKIDPFGKITV
                     MSPPKISKKIIKDIIIEKGDWILKKSEKCKGREEVYKQRMFITGEKFLYLGEEYHLVI
                     KELLRDSVKKSNCRITINEYQIVVQTNDTSTDFIKKSLKSWYKMESERIVLERIDFLK
                     LNCEIMKQLVPASVKVKEQNKRWGSCTAQKNIYINSKISMARLDVIDYVIIHEFSHLA
                     HMNHSKKFYDLVKSIMPDYKDKENWLKINGYKIII"
     misc_binding    2474..2731
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            2844..3083
                     /locus_tag="KR231_003534"
     CDS             2844..3083
                     /locus_tag="KR231_003534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACT domain-containing protein"
                     /protein_id="HBH0005861.1"
                     /translation="MENTVYAKLNQGIDSFLRVAMTLRRREVDIQSISMTVDNMNNSG
                     IKLIVNEEKTSLDSVLNHMKKLHDIREITVERMRH"
     gene            3387..4382
                     /gene="ilvC"
                     /locus_tag="KR231_003535"
     CDS             3387..4382
                     /gene="ilvC"
                     /locus_tag="KR231_003535"
                     /EC_number="1.1.1.86"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketol-acid reductoisomerase"
                     /protein_id="HBH0005862.1"
                     /translation="MKMARMYYEKDVDLEVLKNKKVAVLGYGSQGHAHAQNLRDNGVH
                     VVIGLYDGSKSAQKAKEDGFEVKSVAEATKESDLTMMLMPDEKQKKVYEESVKDNLKE
                     GQTLAFAHGFNIHYNQVQPPEFVDVVMVAPKGPGHLVRNVFTKGSGVPALFAVYQDYT
                     KKATETVLAYAKGIGATRAGVLETTFKEETETDLFGEQSVLCGGISELIKLGYKTLVD
                     AGYQKEVAYFECLHEMKLIVDLIYEGGFERMRYSISDTAEYGDYVSGKRVITDAAKQG
                     MQNVLEDIQNGKFAKAWIKENEEGRENFLKTREEEYNTEIAEVGRNLRSMMSFLK"
     gene            4435..6123
                     /gene="ilvB"
                     /locus_tag="KR231_003536"
     CDS             4435..6123
                     /gene="ilvB"
                     /locus_tag="KR231_003536"
                     /EC_number="2.2.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biosynthetic-type acetolactate synthase large
                     subunit"
                     /protein_id="HBH0005863.1"
                     /translation="MSGAKVILECLKKEGIDTIFGYPGGAVIPLYDALYDYSDDFKHI
                     RTSHEQGLVHAADGYARSTNTVGVCFTTSGPGATNAITGIATAFMDSSPMVVISGQVP
                     TSLLGKDSFQEIDITGATLSMTKHNYLVRNTKELVPTIKEAFRVANSGRKGPVLVDVP
                     KDLFLAEMDFSGEDYDLCQIDDYMDYKSDFDLDDETNIKLLNEAIDIIKESKKPIIYA
                     GGGVKSSDSEEILEKFATKIDTPVLNTLMGLGNIDRKNELSLGMVGMHGSRESNLALS
                     NSDLVIAIGARFSDRVISKSSEFAKNAKIIHIDIDPSEISKNIESNVSLVGDVKLVLS
                     LLIERVESKNNSNWKEEIKRFRKSEGVQTYEFHPQNILKKINEKYETLKKPTVVVTDV
                     GQHQMWAAKYWNFKGNKSFITSAGLGTMGFGLGAAIGTKVGNVDKNVVLVTGDGSFRM
                     NCNELATVANYNVPMLILLLNNRTLGMVRQWQKLFSNQRYSQTDINENVDYVKLVNAY
                     NIDGYKVSSMEELGKALDMIDFNKPVFLQCDIDKDYDVYPIVAPNDALENLICN"
     gene            complement(6484..7614)
                     /locus_tag="KR231_003537"
     CDS             complement(6484..7614)
                     /locus_tag="KR231_003537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HBH0005864.1"
                     /translation="MKGGVRKRSNKWYYYFDLGIVEGKRKKVERVGGNTKKEAEKALR
                     EALNEYENSGIVFEESNISLSDYLDFWYKEYVLLNCKYNTQESYRINIEKHIKPKLGA
                     YKVKALTPAILQNFINRKYKEDYSQNTLQVLKAILHRSLKSAVHPYKHIRENPMQYVS
                     IPKTKSKTETNKIKTITLEEFNQILNIFPQDSFQRIVLLIGFHTGMRRGEIIALKWDN
                     IDLDNKTITVRHTLIKKPNGMFELGQPKTESSCRTIFTGDTLIKALKEHKLYQKKMKL
                     KYGEFYFDSDWVCTKENGQQVNTHTLDTIVRQIRVALNNDFHFHSLRHAHATLLLENG
                     ANIKDIQNRLGHSQLSTTMDTYSHVTDKMKNETVDIFEKITN"
BASE COUNT         3112 a          836 c         1385 g         2646 t
ORIGIN      
        1 ttagtagata caaaccctat atttgcaggt agttccttta atgaaacttc aaatagtgat
       61 acgataaagg tgttaaatgc taagagtatc aactttaaac aagacaatta tgaagtgaat
      121 gtgagtattc ctaaaataaa aggtttaaaa gataaaactt tagagaataa attaaacaat
      181 gagtttttgc aagatgggaa aaaaatttac agtgaatttc aaaataaaat gaaaaaggaa
      241 aataataagg gtcatagata cctaaatgta atccataatg tcaaaaataa ttctaaggac
      301 tttttatcaa tagaaatgac aaaagaagag atagaagctt cctcatctat aactaagaag
      361 cattacactg ttgataaaaa tagaggaata ctattaaatt taccaatatt ttttaaagat
      421 agtagatata ttagagctat aagtgataat ataaaagagc agatgagaaa tcaaattaag
      481 aaagatgata caaaatctta ttttatagac caagataaag actcgccagt gaaagatttt
      541 gaatctataa ataagtatca agatttttat tttaataaaa atggaaatct tgtgattagt
      601 tttgatgaat atgaagtagc tcctggttat atgggagcag tagaatttgt gataccaaat
      661 aaagtaataa aaagactaag atagatatat agaagatttt tagatagact ggtaaggaga
      721 attatatgaa tatatatgaa caagcaataa gattaataga aaataatgag gatttcgcat
      781 ttgctacaat aacgtctcat tcaggttcaa caccacgtga aactggagca atgatgattg
      841 tgaaaaatga ttctactata tttggctcag taggaggagg tagtgtagaa gcagaatgta
      901 taaaacatgc aattaatgtt ataaaaaaca gagaatcaat gttgtataaa tttactctaa
      961 acaaatctga tgtggcaaaa ctaggaatga tatgtggagg tactggagaa atacaaatag
     1021 attttataga tagtaaatta aaaagtaata tagaaaaatt taataagaga ctaaaggaaa
     1081 atacaagtaa agcatatata tttggtgcag gtcatatttc aagagatgtt gctgtgatac
     1141 tatctctttt agaatttaga acagtagtaa tagatgatag agaagaattt gctaatcatg
     1201 aaaggtttcc agaatcagaa gtagtagttt tagattcttt tgaaaacata ccagattttc
     1261 ccactgacga aaatagttat ataattattt taacaagagg tcatctatat gattcaagtg
     1321 ctttagaatg ggctcttaaa agagaggctg gttatatagg tatgattgga agtagaacaa
     1381 aaattggatt gacttatgaa aaactcatga aaaaaggttt taagaaggaa gaattatcaa
     1441 aagtacatgc accaataggc ataaaattga atgctcaaac accagctgaa atagctgtat
     1501 gtatagctgc tgaacttata aattgtagag ctaataagga aaaataaact aatgaacaca
     1561 gggagtaaag atattgatac tttaaaggtt aattttagag ggattgaaat aaaagcagtt
     1621 ttagtatata aaaatagaaa aaatatttct ataaaaatag atccatttgg caaaataact
     1681 gtaatgagtc ctcctaaaat atccaaaaaa ataataaaag atataattat tgaaaaagga
     1741 gactggatac ttaaaaagtc agaaaaatgt aaaggaagag aggaagtata taaacaaaga
     1801 atgtttataa ctggcgaaaa atttctttat ttaggtgaag agtaccatct agttataaaa
     1861 gaactgttga gagattctgt caaaaaaagt aactgtagaa taactattaa cgaatatcaa
     1921 atagttgttc agacaaatga tacaagtaca gattttatta aaaaatcttt aaaatcttgg
     1981 tataagatgg aaagtgaaag aatagtatta gagagaatag attttcttaa attaaattgt
     2041 gaaataatga agcaattagt tccagcgagt gttaaggtaa aagaacaaaa taagagatgg
     2101 ggaagttgta cagctcaaaa aaatatttat ataaactcaa aaatatctat ggcaagatta
     2161 gatgtaattg attatgtaat aatacatgag tttagccatt tagcacatat gaatcactct
     2221 aaaaaattct atgatttagt aaaatccatt atgcccgatt ataaagataa agaaaattgg
     2281 ctaaaaataa atggatataa aataataatc tgaaaacgat tattccaaaa tataggcgta
     2341 aagtataaaa gaagtattat tgtgaaaaaa ataaataatc tgaaaatttt aaaaaaagtc
     2401 attgacattg taaatgatag agaatataat ctatattaac aacaaaacag aattgaaata
     2461 taaaattaaa aaattaaaag caatgacaga gacaacaata ctaatagtgt tatccacaga
     2521 gaaccaatgt tgctgagaat tggtgttaac agtagtataa tgatcactct ggagcttttg
     2581 tactgaatat ttttagtaag tacaaacgta tgtcaacgtt acatgactaa ggttaaggta
     2641 attaattacc cgacctgaaa aaagaggggt agatgtattt tttatatcta caaataaggt
     2701 ggtaccgcgg aatataactt tcgtccttat aagtaatatt tatattgctt ataaagatga
     2761 aagttttttt attttaagtg atataaataa atttaatcca tataaaatta ataaaaaaat
     2821 aataaaaata aggagggatt tttatggaaa atactgtata tgctaaatta aaccaaggaa
     2881 tagattcttt tttaagagtg gctatgactc taagaagaag agaggttgat atacaatcaa
     2941 taagtatgac tgtagataat atgaataatt caggtataaa attaatagta aatgaagaaa
     3001 agacatcctt agattctgtc ttaaaccata tgaaaaaact acatgatata agagagataa
     3061 ctgttgaaag aatgagacat taattaaata tattttataa aactaaagat aaatatgctt
     3121 attttaaaat aaaaaactaa agataaatat taaataagaa aaatcttaga ttaaaatata
     3181 agtgtcattg aatttattag tttatcacag ttaataaatt tattagtttg ttgtagctaa
     3241 taaaaactga aaattctaaa attataattg taagattata taaatttaga atttaaatct
     3301 gttgaataat attaaaacaa tgataatgag tatgaatttc taataaaaat aaatatcata
     3361 aaaataagaa aaagtattgg gaggaaatga aaatggcaag aatgtattat gaaaaagatg
     3421 tggatttaga ggttttaaaa aataaaaagg ttgcagtttt aggttatgga agtcaaggac
     3481 atgcacatgc acaaaatctt agagataacg gtgtacatgt agtgataggt ctttatgacg
     3541 gaagtaaatc agcacaaaaa gcaaaagaag atggatttga agttaagagt gtagcagaag
     3601 ctacaaaaga aagtgatttg acaatgatgt taatgcctga tgaaaagcaa aagaaagttt
     3661 atgaagagag tgtaaaggat aacttaaaag aaggtcagac attagctttt gctcatggat
     3721 tcaatataca ttataatcaa gtacaaccac cagaatttgt tgatgttgta atggtagctc
     3781 ctaaaggacc tggtcactta gttagaaatg tatttacaaa gggaagtgga gttcctgcac
     3841 tatttgcagt atatcaagac tacactaaaa aagctacaga gacagtttta gcatatgcaa
     3901 aagggatagg agcaacaaga gcaggtgttt tagaaactac ttttaaagaa gaaacagaaa
     3961 cagatttatt tggagaacaa tcagtacttt gtggtggaat aagtgaactt ataaaattgg
     4021 gatataaaac gcttgtagat gcaggttatc aaaaagaagt agcatatttt gaatgtttac
     4081 atgaaatgaa actaatagtc gaccttatat atgaaggtgg atttgaaaga atgagatata
     4141 gcataagtga cacagcagaa tatggagatt atgtatctgg taaaagggta ataactgatg
     4201 ctgcaaaaca aggtatgcaa aatgttttag aggatataca aaatggaaaa tttgcaaaag
     4261 cgtggattaa agaaaatgaa gaaggacgtg aaaacttcct aaaaactaga gaagaagaat
     4321 ataatacaga aattgccgaa gttggtagaa atctaagaag tatgatgtca ttcttaaaat
     4381 aaatatatat taaatggatt agtttgaggg aaagagtggt gtatagtagt gcgtatgagt
     4441 ggagcaaagg taattttaga atgtttaaag aaagagggaa ttgacacaat atttggatat
     4501 cctggtggag ccgtgatacc tctttatgat gctctatacg attattcaga tgattttaaa
     4561 catataagga catcccatga acaaggttta gttcatgctg cagatgggta cgcaagaagt
     4621 actaatacag taggagtttg ttttacaaca tctggtccag gagcaacaaa tgccataact
     4681 ggaatagcaa cagcttttat ggattcttca cctatggttg taatttcagg gcaggtgcca
     4741 actagtttat taggaaaaga ttcttttcaa gaaattgaca taactggagc aacattatct
     4801 atgacaaaac ataattattt agttagaaac actaaagaat tagttcctac aataaaagaa
     4861 gcttttagag ttgcaaattc aggtagaaaa ggacctgtac ttgtagatgt tccaaaagat
     4921 ttatttttag cagaaatgga ttttagtggt gaggactatg atttatgtca aatagatgat
     4981 tatatggatt ataagagtga ttttgatcta gatgatgaaa ctaatattaa gcttttaaat
     5041 gaagcaatag atatcataaa agaatctaaa aagcctataa tatatgcagg tggaggtgtt
     5101 aaatcttcag acagtgagga aattcttgaa aaatttgcaa ctaagataga tacacccgta
     5161 ctaaatacac ttatggggct tggaaatata gatagaaaga atgaattatc tcttggaatg
     5221 gttggaatgc atggaagtag agaaagtaat ttagcacttt ctaattcaga tttagtaata
     5281 gcgataggtg cgagatttag tgatagagtg ataagtaaaa gttctgaatt tgctaaaaat
     5341 gcaaaaataa tacacataga catagaccca tctgaaataa gtaaaaatat agaatctaat
     5401 gtatctttgg ttggagatgt aaagctagtc cttagtttat taattgaaag ggttgaaagt
     5461 aagaataata gcaattggaa agaagagata aagagattta gaaagagtga gggtgtacaa
     5521 acatatgaat ttcatccaca aaatatacta aaaaaaataa atgaaaaata tgaaacatta
     5581 aagaaaccca ctgtggtagt aactgatgtc ggtcaacatc aaatgtgggc tgctaagtac
     5641 tggaatttta aaggtaataa aagttttata acatcagcag ggttaggaac tatgggattt
     5701 ggtttaggtg cagctattgg aactaaagtt ggtaatgtag ataaaaatgt agttttagtc
     5761 actggtgatg gaagttttag aatgaactgt aatgaactag ctacagttgc aaattataat
     5821 gtacctatgc ttattttatt actcaataat agaacattag gaatggtaag gcaatggcaa
     5881 aagttatttt ccaatcaaag atactctcaa actgacatta atgaaaatgt ggattatgtt
     5941 aaactcgtaa atgcatataa tattgatgga tataaggtat ccagtatgga agaattagga
     6001 aaggcgctag atatgataga ttttaataaa cctgtatttt tgcaatgtga tatagataag
     6061 gattatgatg tttatcctat tgtagcacct aatgatgcat tggaaaattt gatatgtaac
     6121 taaaacttat actgaatatt gataaaattt tttattaaat ttttattggt attcagtttt
     6181 tgttgtttag agatagattg gcatttttta tttttgcaaa taaatcaatg actatataat
     6241 taagaactta ttaaatttta attatacaat ttagaatagt attacaactt aagtaaatat
     6301 taagttttat ttgttagatt tattattaat accttatatt agttatggtt gttatatact
     6361 ctaaagcctt gaaattacaa gtatatagat gattatataa atttgataat tttagctttt
     6421 aaaatagata aattagattt tgccacccat ttgccaccgt attatatttt tgggtggcaa
     6481 actctaattt gtaatttttt caaatatatc tacagtttca tttttcattt tatcagttac
     6541 atgtgaatag gtatccattg tagttgatag ttggctatgg cccaaacggt tttgtatgtc
     6601 tttaatgtta gcaccatttt ctaataatag agtagcatgt gcatgtctta aagaatgaaa
     6661 atggaagtca ttgtttaaag ctactcgaat ttgtcttact atagtgtcta aagtgtgagt
     6721 attcacttgt tgaccatttt ctttggtaca tacccagtca ctatcaaagt aaaattctcc
     6781 atattttaat ttcattttct tttgatataa tttatgttct tttaatgcct ttattaaagt
     6841 gtcacctgta aatatagttc tgcaagagct ttctgttttt ggttgcccta attcaaacat
     6901 tccatttggt tttttaatca aagtatgtct tactgtgata gttttattat caaggtctat
     6961 attatcccat tttagtgcaa taatttcacc tcttcgcata ccagtatgaa atccaattag
     7021 taaaactata cgttgaaatg aatcttgagg aaatatattt agtatttgat taaattcttc
     7081 taatgtaata gttttaattt tattagtttc tgttttagat ttagtttttg gtatgctcac
     7141 atattgcata gggttttctc gtatatgttt gtaaggatgg actgctgatt ttaatgacct
     7201 atgtaatatg gcttttaata cttgtaatgt attttgagag taatcctctt tgtactttct
     7261 gtttatgaag ttttgtagta ttgcaggagt taaagctttt actttgtaag ctcctagttt
     7321 tggctttata tgtttttcta tgtttattcg gtagctttct tgagtgttgt atttacagtt
     7381 aagtaagaca tattctttgt accaaaagtc taagtagtct gataaactga tattgctttc
     7441 ttcaaatact atgccagagt tttcatattc atttagtgct tctcttaagg ctttttctgc
     7501 ttctttttta gtattgcctc caactctttc tacttttttt ctttttcctt ctactatgcc
     7561 taggtcaaag tagtaatacc atttgttact tctttttctt actccacctt tcataatagt
     7621 atccctccct tttagaatgt atgtttgttt ggtgtttata taaaagagca gattaactgc
     7681 tctttatata cttttgttat gtacaatatt atcttaattt tgtttatttg gtttttactt
     7741 aattattttc ttaatattct tacaattttt tagcttttat gtgtagttta ttataataat
     7801 attgaaatat atatttatta agtaaaaaat ctataaaagt agaataaatg agtttaaaaa
     7861 atatcctcat atatgtagaa atttggcaaa ttagttaata ctaaaaatct attatttcct
     7921 aagtccaaca tgcttttctt ttttgataga aattctaatc tttttagtaa gaagttgat
//
LOCUS       DAEPHU010000121         7908 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 01A10CD0081
            SAMN05941466-rid12468953.denovo.122, whole genome shotgun sequence.
ACCESSION   DAEPHU010000121 DAEPHU010000000
VERSION     DAEPHU010000121.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941466
            Sequence Read Archive: SRR6291087
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 7908)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7908)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068158.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 22:43:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,892
            CDSs (total)                      :: 3,805
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 87
            rRNAs                             :: 8, 1, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 55
            CDSs (without protein)            :: 55
            Pseudo Genes (ambiguous residues) :: 0 of 55
            Pseudo Genes (frameshifted)       :: 21 of 55
            Pseudo Genes (incomplete)         :: 28 of 55
            Pseudo Genes (internal stop)      :: 16 of 55
            Pseudo Genes (multiple problems)  :: 8 of 55
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7908
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941466-rid12468953.denovo.122"
                     /strain="01A10CD0081"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            56..1852
                     /locus_tag="KR231_003538"
     CDS             56..1852
                     /locus_tag="KR231_003538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannonate oxidoreductase"
                     /protein_id="HBH0005865.1"
                     /translation="MGIEYFSKLLESSTEKELLLSKKSNNISTARLISFLIVIAGFAI
                     GFYNKNIVGIFVGVLSIIIFIALLVIHSKVKEEETYFKSKSEVLNKYIKRFGDGWKEF
                     KIDGKEYLKDENSQAKDLDLFGRASLYQYICVANTSYGKNFLAKYLWNENPDENVILE
                     RQRAIKELLSKDDFSIHIQTLSNIIGKEQKNNSDSSIESFIEYGENKNVYIPKWMHIF
                     TWGLPTATILSFIFCMLGFLPVLPVFLLFIIQLGFSGFGYPRLMQTLAPLFSFSRSIQ
                     VYEKMFEVLEKETFESAYLKELQDKLSKGSGVSRGVKQLNSIGNAVNLRYNQILYIIA
                     CGVLMWNYHCAEALERWKGIYGNQIRDWFESIGEFEALISLTVVSHVKENTCFPVIKY
                     EDTPRLKVEEVYHPLIAEKSVIANSIQLNSQTCIITGSNMSGKTTFLRSIGVNLVLAY
                     AGAPVCAKSFDATCMAIFTSMRIQDDVSQGISTFYAEILRIKSMIQYSLKELPMLVLV
                     DEIFKGTNSADRIIGASEAVKKLSKPWVISMVTTHDFELCDLSGSGDVEVVNYHFSEY
                     YVDDKIHFDYKIKDGRCKTTNAKQLMRMAGIL"
     gene            complement(1992..3773)
                     /locus_tag="KR231_003539"
     CDS             complement(1992..3773)
                     /locus_tag="KR231_003539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron hydrogenase small subunit"
                     /protein_id="HBH0005866.1"
                     /translation="MSLVNLTINGKHVSAPSGTSILDAAKLINIKIHNLCHLHMNEID
                     KLDTCASCRVCMVETERGLVPACGTVIKEGMKVQTNSAKALNARRTIVELLLSDHPQD
                     CFVCEKNGDCELQTIAADLGVRKIRYQGSKSFAGKDTSTKSLVKDHSKCILCRRCETV
                     CNDIQTVGALSGVNRGFNTLVSTFFNSDMVETECTFCGQCISVCPTGALTEVDNVPKL
                     WDVLNKKEKTIVVQVAPAVRVAIGEEFGLEPGSISTGKMVAALKALGFEHVFDTNFGA
                     DFTIMEEATEFIERIQKGENLPILTSCCPAWVNFLEHNYPDKLNLASSCKSPQGMFGS
                     IAKNYYAPKILGINPEELYVVSVMPCVAKKYEASREELSESGILDVDLSITTRELAKM
                     IKEAAIDLPNLQDQDFDNPLGKSTGAASIFGASGGVLEAALRTSYEKITNKTLDNVNF
                     TNVRGLKGIREASIDVDGTTVNVCIVNTLKNARKIMDKVRSGECKYHIIEVMACPGGC
                     VGGAGQPYHHGNTEIVDRRANALYEIDRNKAIRKSHENPDLQAIYKDFFGEPNSDVAH
                     KYLHTHYFDKSCVYGECPQECACEEAK"
     gene            complement(3796..5682)
                     /locus_tag="KR231_003540"
     CDS             complement(3796..5682)
                     /locus_tag="KR231_003540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-quinone oxidoreductase subunit NuoF"
                     /protein_id="HBH0005867.1"
                     /translation="MRKVNSFDELKVLADELKPNLSLRKNYSKENVLRRELLVCCDTG
                     CTSSNSLEIVSELENEIKKSGIQDKVSVRLTGCFGFCAQGPIVKVYPDNVFYVKVEPS
                     DAEKIVQSHLIRNTVVEELLYEEESLSKKVEEQEEMSFYKKQLRIALKNCGLIDPDSI
                     EEYIANDGYLALGKCLTSLTPQEVIAEVKTSGLRGRGGAGFPTGSKWEAASKNPAGPT
                     DKKFVVCNADEGDPGAFMDRSVLEGDPHSVLEAMAICGYAIGSDTGYIYIRAEYPKSI
                     ERLKVAIAQAEKYGLLGENILGTGFNFKLELKYGAGAFVCGEGTALMHSIEGRRGEPR
                     MKTYSSSKSGLWKSPTCLNNVETFANIPAIILKGGDWFANLGTEDSSGTKVFALGGKV
                     ENVGLVEVPMGTTLRDIVFEIGGGIPEGKKFKAVQTGGPSGGCIPTEHLDTPIDFGSL
                     SSIGSMMGSGGMLVLDESDCMVDIAKFFLEFTVEESCGKCTPCRIGTTRLLEILTKIT
                     EGNGTLQDLDDLENLAETIQTASLCGLGKAAPNPVLSTLQYFKDEYIAHVVDKKCPAG
                     KCQNLLSYFITDDCKGCTKCSRVCPAGCITGSVKEQHTIDTSKCLKCGACIDNCTFNA
                     IIKK"
     gene            complement(5699..6196)
                     /locus_tag="KR231_003541"
     CDS             complement(5699..6196)
                     /locus_tag="KR231_003541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase subunit E"
                     /protein_id="HBH0005868.1"
                     /translation="MCDFISHNKQLFDELDIFIDSLATKEGALIQVLHEAQGIFGYLP
                     KEVQLHVARKLGVAPAKVYGVVTFYSYFTTEPVGKYKISVCLGTVCFVKGADKILSAF
                     EKQLGIKVGETTSDFKFSLEGLRCLGACGLAPVVTVNGKVYGKVKPDQVSEILDTYRE
                     LELNC"
     gene            complement(6514..7905)
                     /gene="cls"
                     /locus_tag="KR231_003542"
     CDS             complement(6514..7905)
                     /gene="cls"
                     /locus_tag="KR231_003542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003477061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cardiolipin synthase"
                     /protein_id="HBH0005869.1"
                     /translation="MFREKRNINTTLTWLLILVLIPALGFILYIAFGRNISKNNMFRL
                     KEKDDKIIKSNILDTQVKLQSTSEIDSDIHQHKDMIYALANSNNAHYTNNNDVWIYAE
                     SSQFFNSLLEELKKAKKYINIQFYIFKDDKIGTEIIDILIDKAKEGVEVRLLFDAVGG
                     RTLKNSTLSRLKESGVKVGSFFPSFLKIVNFNLNYRNHRKIVVIDGKVGFVGGYNVGD
                     EYLGRNPKFGLWRDTHTKLTGDCVIDLNMRFILDWRYTTKEDLDLEKYFIEEDTNSNH
                     PSENIGIQIVSSGPDISELDEIKYGYLKMIQKARKYIYIQSPYLILDSTFIDTLKIAC
                     LSGVDVRVMIPSKPDHPFVYWASYSYAGELLKFGAKIYTYGQNAFLHAKTIVIDDSIC
                     SIGTANMDIRSFELNFEVNAFMYSSKKALEQRIIFENDILNSKEITLDIYNSRSTYIK
                     IKESISRLLSAVL"
BASE COUNT         2722 a         1334 c         1134 g         2718 t
ORIGIN      
        1 ctagattaat tttatatttg agtttcatta tataacaaga aagttggaat tttttatggg
       61 aatagaatat tttagtaaac ttttagaaag tagtactgaa aaagaattgc tcttaagtaa
      121 aaagtcaaat aacataagta cagcaagatt aatatctttt ttgatagtga tagcagggtt
      181 tgctattgga ttttacaata aaaatatagt aggtattttt gttggagttt tatcaataat
      241 aatatttata gcactcttag ttattcatag taaagtaaaa gaagaagaaa catattttaa
      301 aagtaagagc gaagtattaa ataagtatat taagagattt ggagatggtt ggaaggaatt
      361 taaaatagat ggtaaagaat acttaaaaga tgaaaattcg caagcaaaag atttagactt
      421 atttggaaga gcatcattgt atcaatatat ctgtgtagct aatacatctt atgggaaaaa
      481 ttttttagcc aaatatttgt ggaatgaaaa tccagatgag aatgtaatct tagaaagaca
      541 gagagctata aaagaacttt tatcaaaaga tgatttttct attcatattc aaacactcag
      601 taatataatt ggtaaagagc aaaaaaacaa ttcagatagt agtatagaat cgtttataga
      661 atatggagaa aataagaatg tgtatatacc aaaatggatg catattttta cttggggttt
      721 accaactgca acaatcttat cttttatatt ttgtatgtta ggatttttac ctgttttacc
      781 tgttttttta ctttttataa tccagttagg gtttagtggt tttggatatc caagacttat
      841 gcaaactctt gctccattat tttcatttag tagaagtata caagtatatg aaaaaatgtt
      901 tgaggtttta gaaaaagaga cgtttgagag tgcatatttg aaagaattac aagataaact
      961 ttctaaggga agtggagttt caagaggtgt taaacaatta aattcaatag gaaatgctgt
     1021 aaacctaagg tataatcaga tactatatat aattgcctgt ggtgttttga tgtggaacta
     1081 tcattgtgca gaagctttgg agcgatggaa aggtatatat ggaaatcaaa ttagagattg
     1141 gtttgaatct attggagaat ttgaagctct aataagttta acagttgttt ctcatgtaaa
     1201 ggaaaataca tgttttccag taataaaata tgaagatact ccaagattga aagttgaaga
     1261 ggtataccac ccattaatag cagaaaaaag tgtcatagca aattcgatac aattaaattc
     1321 tcagacttgt attatcacag gttcaaatat gtctggaaag acaacatttt taagaagtat
     1381 cggtgtaaac ttagtgctgg catatgcagg tgctccagta tgcgctaaga gttttgatgc
     1441 gacctgtatg gctatattta cttctatgag aatacaagat gatgtaagtc aaggaatatc
     1501 aactttctat gctgagattc ttagaataaa atcaatgatt caatatagtt taaaagaact
     1561 gccaatgttg gttctagtag atgaaatttt taagggaact aactctgctg atagaattat
     1621 tggagcaagt gaggcagtaa agaaattatc aaaaccctgg gttataagta tggtgacaac
     1681 acatgacttt gagctatgtg acctttcagg tagtggagat gttgaagttg taaactatca
     1741 tttctcagag tactatgtag acgataaaat tcattttgac tataagataa aagatggaag
     1801 atgtaaaact acaaatgcaa aacaacttat gagaatggca ggtattcttt aattaataga
     1861 taggttaatt aaagaataag tctatttaga aatataattt aatttgtgaa attaataagg
     1921 attgtcttaa attacgtaaa agtattttaa gacaatcctt ttttaagaat aaattttata
     1981 ttttgttatg actacttagc ttcttcacaa gcacattctt gtggacactc tccatagaca
     2041 caactcttat caaagtaatg agtatgaagg tatttatggg ctacatcact atttggttct
     2101 ccaaagaagt ctttataaat agcttgtaaa tcaggattct catgagattt acgaatagcc
     2161 ttatttctat ctatttcata taacgcattt gcacgtctat caactatttc agtattacca
     2221 tggtgataag gttgaccagc acctccaaca catccaccag gacatgccat aacttctatg
     2281 atatggtatt tacattctcc acttctgacc ttatccataa tctttctagc gtttttaagt
     2341 gtatttacaa tacacacatt aactgtagtt ccatcaacat ctatacttgc ttccctaatt
     2401 cctttaagac ctctaacatt agtgaagttt acattatcta aagtcttatt agttatcttc
     2461 tcatatgaag tacgtagggc agcttctaaa actccaccac ttgctccaaa tatagatgca
     2521 gcacctgtag attttcctag aggattatca aaatcttggt cttgaagatt aggtaaatcg
     2581 attgcagctt cttttatcat cttagctaac tctctagtag ttatagaaag gtcaacatct
     2641 agtattccag attcacttaa ttcttctctt gaagcttcat attttttagc tacacaaggc
     2701 attacagata caacataaag ttcttcagga ttgattccta atattttagg tgcatagtag
     2761 tttttagcta tagaaccaaa cataccttga ggagacttac agctagatgc taagtttaac
     2821 ttgtctggat aattgtgctc taagaagttt acccatgcag gacaacaact tgttaatata
     2881 ggaagatttt cacctttttg gattctttct ataaattcag tagcttcttc cattatagta
     2941 aaatctgcac caaagtttgt atcaaataca tgttcaaatc caagtgcttt taaagcagct
     3001 accattttcc ctgtagagat tgaccctggt tctaatccaa actcttcacc aatagcaact
     3061 cttacagcag gagcaacttg cactactata gtcttttctt ttttatttaa aacatcccaa
     3121 agtttaggta cattatctac ttctgttaat gctccagttg gacagacaga tatacattga
     3181 ccacagaatg tacactctgt ttcaaccata tcagagttaa agaatgtact aactaaagta
     3241 ttaaatccac gattaactcc agataatgct cctactgttt gtatgtcatt acatacagtc
     3301 tcacatcttc tacataatat acacttagaa tggtctttaa ctaaagattt agtagaagta
     3361 tctttacctg caaaagattt agaaccttga tatcttattt ttcttactcc taaatcagca
     3421 gctatagtct gtaattcaca atctccattt ttttcacaga caaaacaatc ttgtggatgg
     3481 tctgataaca ataattcaac aatagttcta cgagcattta atgctttagc actattagtc
     3541 tgaactttca taccttcctt tataactgtt ccacaagctg gaactaatcc tctctctgtc
     3601 tcaaccatac aaacacgaca agaagcacaa gtgtcaagct tatctatttc attcatatgt
     3661 aaatgacaaa ggttgtgtat ttttatattt attaatttcg cagcatctaa gatagaagtt
     3721 ccactaggtg ctgaaacgtg tttgccatta atagttaaat taactaaact cattgttatt
     3781 cctcctccaa ataagttatt tcttgattat agcgttaaat gtacaattat ctatacaagc
     3841 accacatttt agacacttag aagtatctat tgtatgttgt tccttaacag aacctgttat
     3901 acaaccagca ggacacactc tagaacattt tgtacaaccc ttacagtcat ctgttataaa
     3961 gtaagaaagt aagttctgac atttaccagc aggacatttc ttatctacaa catgagctat
     4021 atactcatct ttgaaatatt gaagagtact taaaacaggg tttggagcag ctttaccaag
     4081 accacataat gaagcagttt gtatagtttc agcaaggttt tctaggtcat ctaaatcttg
     4141 tagagtacca ttaccttctg taattttagt taatatttct aataatcttg tagtacctat
     4201 acgacaaggt gtacatttac cacaagattc ttcaacagta aactcaagga agaacttggc
     4261 tatatctacc atacagtcag attcatcaag aacaagcata ccaccagagc ccatcattga
     4321 accgatagaa cttaatgaac caaagtctat aggagtgtct aaatgttcag ttggtataca
     4381 tccgccagat ggtccacctg tttgaacagc cttaaatttc ttaccttcag ggattccccc
     4441 accaatttca aatacaatat ctcttaaagt agtacccatt ggaacttcaa caagtcctac
     4501 attttctact tttccaccaa gagcaaagac tttagtacca ctagaatctt cagtacctaa
     4561 gttggcaaac caatctccac ccttaagtat aattgcaggt atgttagcaa aagtctcaac
     4621 gttatttaag caagtaggag atttccatag accactctta gaagaactat aagttttcat
     4681 tctaggttca ccacgtctac cttcaattga atgcattagc gctgtacctt caccacaaac
     4741 gaaagcacct gcaccatatt ttaattctaa tttaaagtta aatccagtgc ctaagatatt
     4801 ttcgccaagt aaaccgtatt tttcagcttg agctatggct acttttaatc tttctataga
     4861 ttttggatat tctgctctta tgtatatgta tcctgtatca gaacctatag cgtatccaca
     4921 tattgccata gcttctagta cactatgagg gtcaccttca agtacagatc tatccataaa
     4981 tgcacctggg tcaccttcat cagcattaca tacaacaaac tttttatctg ttggaccagc
     5041 tggatttttt gaagcagctt cccatttaga gccagtaggg aaacctgcac cacctctacc
     5101 acgaaggcca gaagttttta cctctgcaat aacttcttga ggagtaagag aagttaaaca
     5161 tttgcctaga gctaaataac catcattggc aatatattct tctatactat ctgggtctat
     5221 aagaccacaa ttttttaaag ctatacgtaa ctgttttttg tagaaagaca tttcttcttg
     5281 ttcttcaact tttttactta aagattcttc ctcatataat aattcctcga caactgtatt
     5341 tctaattaag tggctttgaa ctatcttttc agcatcagat ggctcaactt ttacgtagaa
     5401 aacgttatca ggataaactt ttacaatagg accttgagca cagaaaccaa aacaacctgt
     5461 caaacgaaca ctaactttat cttggattcc tgatttcttt atttcatttt ctaattcact
     5521 aactatttct agactgtttg aagatgtaca tccagtatca caacaaacaa gtaattctct
     5581 tcttaataca ttttccttag aataattttt tcttaagcta agattaggtt tcagctcatc
     5641 agctaaaact tttaattcat caaatgaatt tactttacgc attatttatt cacccctctt
     5701 aacaattcaa ttctaattct ctataagtat ctaatatttc gcttacttgg tcaggtttca
     5761 ctttaccata aactttacca tttacagtaa caactggagc taaaccacat gcccccaaac
     5821 atcttaaacc ttctaaagaa aatttaaaat cactagtagt ttctccaact tttatgccaa
     5881 gctgtttttc aaaagcactt aagattttgt cagcaccttt tacaaaacat acagttccta
     5941 gacagacact gattttatac ttacctacag gttctgtagt aaaataagaa tagaatgtaa
     6001 caaccccata tacctttgca ggagctactc caagttttct agcaacatga agttgaactt
     6061 cttttggaag atatccaaat ataccttggg cttcatgtag aacttgtatt aacgcacctt
     6121 cctttgttgc aagagagtca ataaatatat ctagttcgtc aaataattgc ttgttgtgtg
     6181 aaataaaatc gcacataaca aatccccctt ttctttttaa agttattatt tttcataaaa
     6241 taattaacca tgagttgacc ccaacattat gtgggtgaac aaaaccaaaa caataaagaa
     6301 agaataatat acaacaattt ctttatttat aaaaacaatg caaaaaagtt acctattaaa
     6361 aataaaaact atactagtct attataatat aaaataattc agaatagtta aaaaaaataa
     6421 aaaaaatgag ctaaattcaa taaaaaaaaa ataatacata taaaaaactt taaaaaataa
     6481 accaaaatgt aaaattttta taaaataaaa gatttataaa actgctgata atagtcttga
     6541 aattgattcc ttgattttta tataagtaga cctagaatta tatatatcta atgttatttc
     6601 cttagaattt aaaatatcat tttcaaatat aattctttgt tccaatgctt tttttgaaga
     6661 gtacataaat gcattaactt cgaaattaag ctcaaaactt ctgatatcca tattagctgt
     6721 tcctatagag catatagagt catctataac tattgtctta gcatgtaaaa atgcattttg
     6781 accataagta tagattttag ctccaaactt taaaagttct ccagcatatg aatatgatgc
     6841 ccagtataca aagggatggt caggtttaga aggaatcata actctcacat caacaccaga
     6901 taaacaagct atttttaaag tatctataaa agttgagtca agtattaaat aaggactctg
     6961 tatgtatata tactttctag ctttctgaat cattttaagg taaccatatt taatctcatc
     7021 aagttctgat atatctggac cacttgatac tatctgaatc ccaatatttt cagaaggatg
     7081 attagaattt gtatcttctt ctataaagta cttttctaaa tctaagtctt ctttagttgt
     7141 atatctccaa tcaaggatga atctcatatt taggtcaatt acgcaatcac cagtaagctt
     7201 agtatgtgta tctctccata gaccaaattt tggatttcta cctaaatatt catcaccaac
     7261 attatatcca cctacaaatc ctaccttacc atcaatgaca acaatttttc ggtgatttct
     7321 atagtttaag ttaaagttta caattttcaa gaatgatggg aagaagcttc caactttaac
     7381 accactttct ttaagtctgg aaagtgtact attttttagt gttctaccac caactgcatc
     7441 aaataaaagt cttacttcaa caccttcttt agctttgtct ataagaatgt ctattatttc
     7501 agttccgatt ttgtcatctt tgaaaatgta aaattgtatg tttatatatt ttttagcttt
     7561 tttaagttct tcaagaagac tgttaaaaaa ttgactagat tcagcataaa tccacacatc
     7621 gttattattg gtataatgag cattatttga attagccaat gcataaatca tatccttatg
     7681 ttgatgtata tctgaatcaa tttcagatgt agattggagt ttaacctgag tatctagtat
     7741 attacttttg attatcttat catccttttc tttcaatcta aacatattgt tttttgaaat
     7801 atttctgcca aaagctatat aaagtatgaa tccaagagca ggaatcaata ctaatataag
     7861 aagccatgtt aaagttgtat ttatgtttct tttttctcta aagataag
//
LOCUS       DAEPHU010000122         7903 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 01A10CD0081
            SAMN05941466-rid12468953.denovo.123, whole genome shotgun sequence.
ACCESSION   DAEPHU010000122 DAEPHU010000000
VERSION     DAEPHU010000122.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941466
            Sequence Read Archive: SRR6291087
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 7903)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7903)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068158.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 22:43:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,892
            CDSs (total)                      :: 3,805
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 87
            rRNAs                             :: 8, 1, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 55
            CDSs (without protein)            :: 55
            Pseudo Genes (ambiguous residues) :: 0 of 55
            Pseudo Genes (frameshifted)       :: 21 of 55
            Pseudo Genes (incomplete)         :: 28 of 55
            Pseudo Genes (internal stop)      :: 16 of 55
            Pseudo Genes (multiple problems)  :: 8 of 55
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7903
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941466-rid12468953.denovo.123"
                     /strain="01A10CD0081"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            406..1707
                     /locus_tag="KR231_003543"
     CDS             406..1707
                     /locus_tag="KR231_003543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HBH0005870.1"
                     /translation="MGKSKDVEIEKSILGTILLDNKLSYKLDELNENMFMNDICLEIF
                     KIMKELKKENIVIDVATVKSKIDRKSLAIKTSDVTNLITWGQNFGLDGHIKILKENLA
                     RRSINQNCQNLLHSLNLGENIDTCIYKFESNIKEILDKDTYENDDVNSIAGKVLDFLE
                     NKKDIGFKFGIKLLDTTIGGLFKGELTTIAAKSGVGKTALALQIMLNSFKQGKKTLFI
                     SREMTSEQVFMRNICRVTGVSTRNMKSKEIDENDWKLIVNAIGDLSENNLIYINDKID
                     TISAIRKRIRQVKPDLLIVDYVQLLTSQKSMDKREREVATFSRELKNMTLDFNIPVIQ
                     LSQLNDEMKDSRPYGDRPMRDSKAIYHDSNNVVYIHQLKGSDYEEAVRDIGESEEAVR
                     ASEYRGIKMVDLIVAKCRDGQTRHKHFCYFGDKLHFQELNY"
     gene            1783..2058
                     /locus_tag="KR231_003544"
     CDS             1783..2058
                     /locus_tag="KR231_003544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HBH0005871.1"
                     /translation="MLELRKIIELLEEHKIEVSIPKELHKYSLLEYLELCQQSGGTYF
                     YIKTLEGALKEARNELMIKLFNGKNYMELARMFEMSVINVRHIVRKK"
     gene            3501..3731
                     /locus_tag="KR231_003545"
     CDS             3501..3731
                     /locus_tag="KR231_003545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S binding protein"
                     /protein_id="HBH0005872.1"
                     /translation="MSNKKKKYANILANECVACGSCIKACPRSAISVPCGISAKINRD
                     LCVGCGICEKICPASVIEIITILKEEEGKCHE"
     gene            3724..4305
                     /locus_tag="KR231_003546"
     CDS             3724..4305
                     /locus_tag="KR231_003546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S binding protein"
                     /protein_id="HBH0005873.1"
                     /translation="MNNKKHWYDYLWIFSSIYLILGFVNIIFAWIGLICFFVPLAISI
                     VKGNKAYCNKYCGRGQLFNLLGNKLKLSRNRDIPKFIRSKWFRYGFLTFFMVMFANML
                     FSTYLVFEGSRNFKEVVTLLWTIKMPWQWAYHGTLVSPWVVQFAFGFYSVMLTSTVLG
                     LITMILFKPRSWCVYCPMGTMTQMICKAKSKSI"
     gene            complement(4880..5557)
                     /locus_tag="KR231_003547"
     CDS             complement(4880..5557)
                     /locus_tag="KR231_003547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HBH0005874.1"
                     /translation="MISQNEIDILTHSLPFWDKLTDLQKELLISSANTSHYKKGNPVH
                     CGDSDCIGILIIKSGTVRTYILSDEGREVTLFRLDDGDVCILSASCILKTITFDVYVD
                     AETDCDIIQISSSVFAKLSTENIHAELFSYKLATERFSDVMWAMQQILFMSFDKRLAS
                     FLIDEIAKNGSSTINMTHEQIAKYMGSAREVVSRMLKYFAREGIVSLSRGGIKVLDKD
                     KLRSLTL"
     gene            complement(5746..7110)
                     /locus_tag="KR231_003548"
     CDS             complement(5746..7110)
                     /locus_tag="KR231_003548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HBH0005875.1"
                     /translation="MKESNKRIELLGSAPISKALLSMGLPTMIGMMITALYNLVDAYF
                     VGGLGTSQMGAISVAFPLGQLVVGLGLLFGNGAASYIARLLGHGDNEKAGKVVSTSIY
                     SSIIVGTLVIIVIMIFLNPILKLLGATKSIMPYAISYASIYVVSSIFNIFNVTMTNIV
                     TSEGAAKTTMCAMLLGALLNMILDPIFIYTFGLGVRGASIATAISQIASTLVYVGYIL
                     SKKSIFSFRINECCFSKEIFSEILKIGIPTLIFQLLTSLAITLTNMEATKYGDSVIAG
                     MGAVTRITSLGSLVVFGFIKGFQPIAGYNFGSKNYDRLHIAIKTSILWTTIFCVVLGL
                     ILILFPKSIISQFTSGDILLIENGSKALRANGFSFMLFGFYTVYSTLFLALGKAKEGG
                     FLGMCRQGVCFIPIILIIPVFYGLNGILYAQPIADLMAAIIAGFMSIRLHKELNLLKI
                     NGMH"
     gene            7238..7759
                     /locus_tag="KR231_003549"
     CDS             7238..7759
                     /locus_tag="KR231_003549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HBH0005876.1"
                     /translation="MATIDLIVLGIVKQQPKSAYDIQKAVEYRNISRWVKISTPSIYK
                     KVIQLEQKGYIESKTVKNGKMPEKAVYSLTELGETHFLDLMFDTSSKPINILLDFNAV
                     IVNLNSLTPEKQKLCLNNIEENVQELKKTIEENISIKTEVPDTAKAVLEQQLVLAQAL
                     ETWINSLKDNMGN"
BASE COUNT         3090 a          882 c         1363 g         2568 t
ORIGIN      
        1 aagatattac tatcaagtag tgaattatat tgaacgatat attaataatt ggaagtaagt
       61 tatatcaaat aagatattac tatcaagtag tgaattatat tgaacgatat attaataatt
      121 ggcagtaagt tatatcaaat aagatattac tatcaagtag tgaattatat tgaacaatat
      181 attaataatt ggtagtaaag tatatcaaat aagatattgc tattatgtag taaattatat
      241 aaaacaatgt atcagaataa atagtatatt aataatttgt agtatatcat gacgaataat
      301 acagtcataa caaatagtga gtcataacaa ataatgtatt tataattgat aatgtattta
      361 aaaatcaaaa tataaaaact tataaggaaa gagagattaa tttatatggg taaatcaaaa
      421 gatgttgaaa tagagaagtc tattttaggc acaattcttt tagacaataa attaagctat
      481 aagctagatg aattaaatga aaacatgttt atgaatgata tatgtcttga gatatttaaa
      541 attatgaaag aacttaaaaa agaaaacata gtgattgatg tggccactgt gaaatcaaag
      601 atagatagaa aatctctagc aataaaaacg agtgatgtga ctaatctaat tacttggggt
      661 cagaattttg gtcttgatgg tcatattaaa attttaaaag aaaatttagc tagaagaagc
      721 ataaatcaaa attgccaaaa ccttttacac agcctaaacc ttggagaaaa tatcgatact
      781 tgtatttaca aatttgaaag taatataaag gagattttgg acaaggatac ttatgaaaat
      841 gatgatgtaa atagtatagc agggaaggtg cttgattttt tagaaaacaa aaaagatatt
      901 ggatttaaat ttggtataaa attacttgat accactatag gaggtctttt taaaggagag
      961 ctaaccacaa tagcagctaa atcgggggtt gggaagactg ctttggcact tcaaataatg
     1021 ttaaattcat ttaagcaagg taaaaaaact ttatttataa gtagagaaat gaccagtgag
     1081 caagtattta tgagaaatat atgcagagta actggtgtaa gtacaaggaa tatgaaatct
     1141 aaagaaatag atgaaaatga ttggaaactt attgtaaatg ctataggtga tttaagcgaa
     1201 aataacttaa tttatattaa tgataagata gatacaatta gtgcaattag aaagaggata
     1261 aggcaggtaa agccagattt attaatagtg gattatgtgc aactccttac atctcagaaa
     1321 agcatggata agagagaaag ggaggtagct actttttcga gagaacttaa aaatatgact
     1381 ttagatttta atatacctgt aatccaatta agtcagttaa atgatgaaat gaaagattca
     1441 agaccttatg gagatagacc tatgagggat agcaaagcca tctaccacga tagcaacaat
     1501 gtggtttata tacatcaatt aaaggggagt gattatgaag aagcagtgag agatattgga
     1561 gaaagtgagg aggcagttag agcatcagaa tacaggggaa ttaagatggt tgatttaata
     1621 gttgcgaagt gtagagatgg acagactagg cataagcatt tttgttactt tggggataag
     1681 ttacattttc aagaactaaa ttattaggtc aataaagtag taataacaag cttattaaaa
     1741 gtcgggaaat agcaaataga ttataaaata tgaggtgaaa atatgttgga attaagaaaa
     1801 attatagaat tacttgaaga acacaagata gaagtaagta ttccaaagga gttacataag
     1861 tatagtttat tggaatacct tgaattgtgt caacaaagtg ggggaacata tttttatatt
     1921 aaaacactgg aaggggcttt aaaagaggct agaaatgagc ttatgattaa attgtttaat
     1981 gggaaaaatt atatggaatt agcgaggatg tttgaaatga gtgttattaa tgtcaggcat
     2041 attgttagaa aaaaatagat atttttggag aatacaagtg tgatatactt ctgaaataga
     2101 agttattata gttgaaataa aattgtggtt aataaattaa agttgtgtat aagtttaaga
     2161 ttatagagga gtataagtgt gattaacagc atgattttgt gaataaaatt gaggatatat
     2221 atgagttaaa tgtgtgatta ataaggtaag gttgtgtata agattatgag tatttaaaag
     2281 gaggggctat aattaatagt gtagagttgt gtgtttgctt aagattatat aataatttaa
     2341 tagattaaac tatactaata aggtaaaatc gtgtgtttag ttaaagctta ttataaaatc
     2401 ttgatatgtg attaatgatg caatatgtga ataaagttaa gattataata gatttaacct
     2461 gtggctaata gaataaaatt gtgaataaag ttaagattat aataggttta acctgtgatt
     2521 aatagagtaa gagtgtaaat agagataaac ttcaatatga gcttaaccta tgattaatag
     2581 agtaagagtg taaatagaga taaacttcaa tatgagctta acctatgatt aatagagtaa
     2641 gagtgtaaat agagataaac ttcaatatgg gtttaacttg tgattaatag agtagggtgt
     2701 aactaaagat aaacttcaat atgagtttaa cttgtgatta atagagtaag gtgcaactaa
     2761 agataaactt caatatgagc ttaacctatg attaatagag taagaatgta aatagagata
     2821 aacttcaata tgggcttaac ttgtggttaa tagagtaaga gtgtaactaa agataaactt
     2881 caatatgggt ttaacttgtg gttaatagag taagaatgta aatagagata aacttcaata
     2941 tgagcttaac ttgtgattaa tagagtaaga gtgtaaatag agataaactt caatatggga
     3001 ttaacttgtg attaatagag taagagtgta actaaagata aacttcaata tgagcttaac
     3061 ctatgattaa tagagtaaga atgtaaatag agataaactt caatatgggt ttaacctgtg
     3121 gttaatagag tagggtgtaa ctaaagataa acttcaatat gagtttaact tgtggctaat
     3181 agaataagat tgtgaataaa gttatagttt tagatgggta ttaacctgtt actaatagaa
     3241 tatgattagg tgtaaaatta tagagctgta taagaaaata ttatagatat attaaatatt
     3301 agataataaa tatttatata gatacacaaa agaaaaggcg atatgaagct aaacttaatg
     3361 acttcatatc gttttttatt tgaaactcct ttgtatttag agtgtgattt ttaatattga
     3421 ggttttatgt gattaagtca cagataaaaa gtaagtatct tgatataatt cttatagatt
     3481 aataatatag ggaggttatt atgtctaata aaaaaaagaa gtatgcaaat attttagcaa
     3541 atgagtgcgt tgcttgtggt agctgtataa aagcatgtcc aagaagtgct atctcagttc
     3601 catgtggcat tagtgcaaaa attaatagag atttatgtgt tggatgtggg atttgtgaaa
     3661 agatatgtcc agcatctgta attgagatta taacaatatt aaaagaggaa gaaggtaagt
     3721 gtcatgaata ataaaaaaca ttggtatgac tatttatgga ttttttcttc aatatatttg
     3781 atattgggat ttgtaaatat tattttcgct tggattgggc taatttgttt ctttgttcca
     3841 ctagctattt ctattgttaa gggaaataaa gcttactgta ataagtattg tggaagaggg
     3901 caactgttta atttgcttgg aaataaattg aagctgtcaa gaaatagaga tattcctaaa
     3961 tttattagaa gtaagtggtt tagatatggg tttttgacat tttttatggt aatgtttgcc
     4021 aatatgcttt tttcaactta tttagtgttt gaaggaagta gaaattttaa agaagtagtg
     4081 actttgttgt ggactataaa aatgccttgg caatgggcgt atcatggaac tttagtttca
     4141 ccttgggtgg tacagtttgc atttggtttt tatagtgtta tgcttacatc aactgttctt
     4201 ggtttgatta ctatgatatt gtttaaacct cgttcatggt gtgtttattg ccctatgggt
     4261 actatgactc agatgatatg taaggcaaag agtaagtcta tatagaaagg ctttatgtga
     4321 tatttacagt tttgttagag atgagtagta ggtttgaata tatatgacaa atatatgagt
     4381 ataggggcat agatttagtt tgtgtaaggt aaactgattt atgcttcttt tttatgtctt
     4441 agattattgg ctaagtggaa acaatgaatt tagatattaa gaattattca gttatttgaa
     4501 gaaaatagaa taataattaa cattatatga atggatattc attacatata agccagttaa
     4561 tagcaagatt tatttaatat gaaataggtc aagtatttaa actaaataag gtcatgacaa
     4621 ttaatataag tatagatata aaaagattag aagttataac ttataaaagg tattctatat
     4681 aaatagtatg tggaaaatag tcaaattaac ttattagaaa caaaaaatat acataaaaaa
     4741 ataaatgtaa atatcaaata agatactata taaaaataga tataagtatc ttttttatta
     4801 ttgaaattat gaaaatatat ttgatttcac acaaaaaaga gtgcctcatg aactaaaaag
     4861 ttcattttga gacacacttt tacagtgtca aagaacgaag tttatcctta tccaatactt
     4921 ttataccacc acgagataaa gacacaatac cttctctagc aaaatatttc aacattctcg
     4981 atacaacttc tctggcacta cccatatact tagcaatttg ctcatgagtc atatttatag
     5041 tgctactgcc atttttagct atctcatcaa ttaaaaaaga tgccaaacgc ttatcaaaac
     5101 tcataaaaag aatttgttgc atagcccaca taacatcaga aaaacgttcg gtagctaatt
     5161 tatatgaaaa taactctgca tgaatatttt ctgtagataa ttttgcaaaa acagaggaac
     5221 taatctgtat aatatcgcag tccgtttcag catctacata gacatcaaaa gttattgttt
     5281 ttagaataca ggaagctgat aaaatacata catctccatc atcaagtcgg aacagtgtaa
     5341 cctctcgacc ttcatctgaa agtatgtatg tacgtactgt tccagacttt ataatcaaaa
     5401 taccaataca gtcactatca ccacaatgta ctggattccc ttttttgtaa tgcgaggtat
     5461 ttgctgaaga aattaataat tctttttgta agtcagtaag tttatcccaa aaaggcaagc
     5521 tatgtgtaag tatatcgatt tcattttgtg aaatcataca atatctcctt tcttaaattg
     5581 ttataatccc atgatacaag tgaatagata aattgacaag tagtttgtta ataggattat
     5641 ttagtcagat agtaatagta tgatttatgt agaaaaaata tgataatata tattcttgct
     5701 attaatgaga aggtaatatg ttttgatgat agtaggtttg tataactaat gcataccgtt
     5761 tatttttaaa agattaagtt ccttatgtaa ccttatagac ataaaaccag caattatagc
     5821 agccatcaaa tcagctattg gttgtgcata taagatacca tttaacccat agaatacagg
     5881 aataatcaaa attataggga taaaacagac accttgtcta cacataccta aaaatccacc
     5941 ttcctttgct tttcctagtg cgaggaataa tgtagaatac actgtataga atccaaatag
     6001 cataaatgaa aacccatttg ccctaagagc tttactacca ttttctatta atagaatgtc
     6061 accacttgta aattgtgaaa ttatagattt tgggaagagt atcaatataa gaccaagcac
     6121 tacacaaaat attgtagtcc ataatatgga agtttttatt gctatatgta atctatcgta
     6181 gttctttgaa ccaaaattat aaccagcaat tggttggaaa ccttttataa aaccaaatac
     6241 aacaagacta cctaaagacg ttattcgtgt tacagcaccc attccagcta tcacagaatc
     6301 accatacttt gtagcctcca tattagttaa tgtaatggca agactagtca ataattgaaa
     6361 tattaaggta ggtatgccaa tttttaggat ttctgaaaaa atttcttttg aaaaacagca
     6421 ttcgttaatt ctaaaactaa atatactttt cttgcttaaa atatatccta cataaacaag
     6481 tgttgaagca atctgtgaga tagctgttgc aatagaagca ccccttaccc ccagaccaaa
     6541 agtataaatg aatattgggt ctaaaatcat attaagcaaa gcacctaata acatagcaca
     6601 catagttgtt ttagcagctc cttcacttgt gacaatatta gtcatagtga cattgaatat
     6661 attaaaaata gatgacacga cataaatgct agcataagat attgcataag gcataatact
     6721 ttttgtagct cctaacaatt ttaaaattgg attgagaaaa atcataatca caataataac
     6781 taatgtaccc actataatac tactgtaaat agatgtactt accacttttc ctgctttttc
     6841 attatcacca tggcctaaaa gtctggcaat atatgaagca gctccatttc caaacaataa
     6901 tcctaatccc acaacaagct gacctaatgg aaatgcaacg gatatagctc ccatttgact
     6961 tgttccaagt ccacccacaa agtatgcatc aaccaaattg tataatgcag ttatcatcat
     7021 acctatcatg gtaggtaatc ccatagataa caatgctttt gagattgggg cagaccctaa
     7081 taattcaatt cttttgttac tttctttcat acttaacact cctcttctat tgacattaag
     7141 tctaaattat aatactataa attatagtaa gtatggaaaa tagtactata atttatagta
     7201 tttgtcaata gtaagaaaac taaaggagat gatttttatg gctacaatag atttaattgt
     7261 attgggaata gtaaagcaac aacccaagag tgcttatgat attcaaaagg cagtggaata
     7321 caggaatata tcacgttggg ttaaaataag tacaccatca atttataaaa aagtaattca
     7381 attagaacaa aagggatata ttgaaagtaa aactgtgaag aatggaaaaa tgccagaaaa
     7441 agcagtttat tcattaactg aattaggtga gacacatttt ttagatttaa tgtttgatac
     7501 atctagcaaa ccaataaata ttcttttaga ttttaatgct gttatagtaa atttaaatag
     7561 ccttacacca gaaaaacaga aattatgtct caataatatt gaagagaatg ttcaagagtt
     7621 aaagaaaact attgaggaaa atataagtat aaagacagaa gtaccagaca cagcaaaagc
     7681 agtgttggag caacagttgg tgctagcaca agcattggaa acctggataa attctttaaa
     7741 agataatatg ggaaattaga attagagaag ctaacttaat aatcattaaa caaaaaccag
     7801 catatttaat aatgagatat tagaaaaaat aaaacaaatg atataaactg aaaagtatat
     7861 ttaaaataaa gctcacttaa ttgagggaga atgttaaact ttt
//
LOCUS       DAEPHU010000123         7807 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 01A10CD0081
            SAMN05941466-rid12468953.denovo.124, whole genome shotgun sequence.
ACCESSION   DAEPHU010000123 DAEPHU010000000
VERSION     DAEPHU010000123.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941466
            Sequence Read Archive: SRR6291087
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 7807)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7807)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068158.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 22:43:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,892
            CDSs (total)                      :: 3,805
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 87
            rRNAs                             :: 8, 1, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 55
            CDSs (without protein)            :: 55
            Pseudo Genes (ambiguous residues) :: 0 of 55
            Pseudo Genes (frameshifted)       :: 21 of 55
            Pseudo Genes (incomplete)         :: 28 of 55
            Pseudo Genes (internal stop)      :: 16 of 55
            Pseudo Genes (multiple problems)  :: 8 of 55
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7807
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941466-rid12468953.denovo.124"
                     /strain="01A10CD0081"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            34..2268
                     /locus_tag="KR231_003550"
     CDS             34..2268
                     /locus_tag="KR231_003550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EAL domain-containing protein"
                     /protein_id="HBH0005877.1"
                     /translation="MQNHNYIKMLNKKVEVLSKELDSRNFKLKTLNEIDFFSKIPNRE
                     FMYQHIDDCISKNIHIGIMLLNIDNFKLFNDIYGYLVGENLLITLTQNLLHFIPESKG
                     IVAYLKGEGFLIVLPNVSNKELNNMGATIIESARELKIKLPNEKEIYSNVTFSIGSTI
                     WNGEPNMTTLMLFNQVYSALKKAKSEGKNRYILFDFKDNSFYNKLENDKEFLSEISHV
                     LQTKQIEVFYQPLYNIKNNTIVGCEALARWRHPIKGLLTPDKFIPLFEQFGLITELDL
                     HLFEENCKNIRRWIDNNDVFVPICCNFSRLHFFNPNFPSMLKGITEKYSVSTSNFSIE
                     ITENILIENTNTIIQQLAELRSYGFSVSMDDFGSGYSSFGMLQNLPFDIIKIDRIFLS
                     HNLNDFKNTTILYSIINIARALGMLTVCEGVETEQHVEFIKSINCDIAQGYYYAKPME
                     CKEFEKLLSKENNSEKMFIKYSDIGKSLIEKIFDGFFIMQDMKKLRANVTEDIQWFDF
                     YNKTEITSFPKVIEHFEKHIKGKKFSILYKSITPHNTESDSLLISGEAVLSDEASEHQ
                     KYSNFYFSANCIISENKLLLAKLHLDLIKTAGYINEFESYSIPKMTNTHLDESNILSQ
                     FYSMLPVGIIRYDLFGDMIITYMNEEMFDIIGYTKEQFFGEMGGNLRAIVHPDDLDFV
                     YKKSLDMIDTNKIEPFLYRFIKRDGQIVTVMYTQCNLSAIDGRSIAQGMYVDVNKIKN
                     LTKI"
     gene            2299..3132
                     /locus_tag="KR231_003551"
     CDS             2299..3132
                     /locus_tag="KR231_003551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GGDEF domain-containing protein"
                     /protein_id="HBH0005878.1"
                     /translation="MFKEIFLRTFPGFLIIRDSNYRIIFINDNLKNLIKSYMQDNPLG
                     MTNIEIAKKLPDNIAKFFTDSHNIQLDWEKNYPYDKISNWILEFKKDTTSYWNVLEYK
                     VDVDEKTYIITMANDITKLYEENKRNLHYSITDPLTGAYNRKYLNDRFDIFIGDYIVL
                     IDLDNFKMINDYEGHNVGDKILCDFVSLLNKELINSTSIIRLGGDEFIVIFSSDVDKN
                     YVYSQLEALRENFLKVFSKYKYLSFSYGVDTVKRNLKLTIVELDKKMYKNKKKFDKND
                     Y"
     gene            3372..5105
                     /locus_tag="KR231_003552"
     CDS             3372..5105
                     /locus_tag="KR231_003552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diguanylate cyclase"
                     /protein_id="HBH0005879.1"
                     /translation="MSILLKKAPKLAKHIITSFYINRDIDEVLKYLCENVTWIGPGEQ
                     EFLTSFNEIKNYFYAGQDEIPSCDINNDIFETVSEDENRCMVLGRYTVRTKENTQMIL
                     EVNQRCTFEIIEDRGKLLVKHMHISNPYGEMQLDEYFPTKIGTQSYDYLQRLLKEKTE
                     VIEMITNNINGGLKGSNDDNTYSFFYVNEGLPKILGYTYDEFMEMSGGSAVGAVYPPD
                     LPKALEDCERCFAKGPTYSSEYRIRKKDGTLMWVLDSGMKSLNSDGIVKINSIITDIT
                     QLKNIESELKLERERYRIALQNITDIMFEYDIENDTLIKYQRVEIDKKIELENFETKN
                     YSKLLESGKIIHLDDIGKLLEVLHGNLRETIEIRQVNSLTKNEWRWIRVQCSVIYDSD
                     HNPIKTIGVLKDITEDKSKLESLINQAQRDPLTQLYNQRVSQNLIEEYLCSSDSKNND
                     ALLVIDIDDFKTVNDTFGHLEGNEVLVAVSKILLHNTHDKDIVARIGGDEFTIFIKSL
                     TKDLIIKITNDILNDASKIKVKDNHKITLSIGIAFTDDSTKLYKDLFSKADKALYLSK
                     ADGKNCYSTYE"
     repeat_region   5437..6055
                     /inference="COORDINATES: alignment:crt:1.2"
                     /inference="COORDINATES: alignment:pilercr:v1.02"
                     /rpt_family="CRISPR"
                     /rpt_type=direct
                     /rpt_unit_range=5566..5594
                     /rpt_unit_seq="atttacataccacttagttaatataaaac"
     gene            complement(6585..6689)
                     /locus_tag="KR231_003553"
     CDS             complement(6585..6689)
                     /locus_tag="KR231_003553"
                     /inference="COORDINATES: protein motif:HMM:NF024729.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HBH0005880.1"
                     /translation="MDDYIYYYNNFRYQNRLNSMSPFEFRKYLSTERA"
     gene            7314..7559
                     /locus_tag="KR231_003554"
     CDS             7314..7559
                     /locus_tag="KR231_003554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0005881.1"
                     /translation="MNQKKIKISIKMVIIGIFAVIIAFVLSRLFVEYIDELLRSNWQY
                     QLFESESSYIVFANCIMFSNILLEIFLIYICRKFRKI"
BASE COUNT         3127 a          936 c         1038 g         2706 t
ORIGIN      
        1 attaaaattt aaagtatctt atggaggaat accatgcaaa atcataatta tataaaaatg
       61 ttaaataaaa aggtagaagt attatctaag gaattagata gtagaaattt taaattaaaa
      121 accttaaatg aaatagattt tttttctaaa ataccaaaca gagaatttat gtaccaacat
      181 attgatgact gtatttcgaa aaatatacat ataggaatca tgttattaaa tatcgataac
      241 tttaaattat ttaatgatat atatggatac ctagtcggag aaaatttatt aattactcta
      301 actcaaaacc tattgcactt tattccagaa tcaaagggaa tagtcgctta tttaaaagga
      361 gaaggttttt taattgtact tccaaatgta tcaaataaag agttaaataa tatgggtgca
      421 actattatag agagcgcccg agaattaaaa ataaaacttc ctaatgaaaa agaaatatac
      481 tccaatgtta catttagtat cggcagcact atctggaatg gtgaaccaaa catgactact
      541 ttgatgcttt tcaaccaagt atatagtgct ttaaaaaagg ctaaaagtga aggtaaaaat
      601 agatacattc tatttgattt taaagataat agtttttaca ataaattaga aaatgataag
      661 gagttcttat cagaaatatc acatgttcta caaactaaac aaattgaagt attttaccaa
      721 ccactttata atataaaaaa taatactata gttggatgtg aggcacttgc aagatggaga
      781 caccctatta aaggacttct tactccagat aaatttattc ctttatttga acagtttggt
      841 ctgataacgg aattagattt gcatttattt gaagagaact gtaaaaatat aagaagatgg
      901 attgataaca atgatgtttt tgttccaatt tgttgtaact tttctcgtct tcattttttt
      961 aaccctaatt ttccaagtat gctaaaaggt attactgaaa agtacagcgt ctctacatca
     1021 aattttagca ttgaaataac agaaaatata ttaatagaaa atacaaatac aattattcaa
     1081 caactagctg aacttcgttc ttatggtttt tctgtatcaa tggacgattt tggttctgga
     1141 tattcatctt ttggtatgtt gcaaaatcta ccttttgata taatcaaaat tgataggata
     1201 tttttatctc ataatttaaa tgattttaaa aatacaacca ttttgtactc tataataaac
     1261 attgcaagag ctcttgggat gcttacagta tgtgaaggtg ttgaaacaga acaacatgta
     1321 gaatttatta aaagtataaa ttgtgatatc gcccaaggtt attattatgc aaaacccatg
     1381 gagtgcaaag aatttgaaaa attactatct aaagagaata attcagagaa aatgtttata
     1441 aaatattctg atataggaaa atctttaata gagaagatat ttgatggatt ttttattatg
     1501 caagatatga aaaaactaag agctaatgtc actgaagaca ttcaatggtt tgatttttac
     1561 aacaaaactg aaattacatc ttttcctaaa gtaatagagc attttgaaaa acatattaaa
     1621 ggtaaaaaat tttctattct ttacaaaagt ataaccccac ataatactga atcagattca
     1681 ttattaatta gtggagaagc cgttttatca gatgaagctt ctgaacatca aaaatatagc
     1741 aatttctact ttagtgcaaa ttgtataatt tcagaaaata aattactctt agcaaaatta
     1801 catttggatt taattaaaac tgctggctat ataaatgaat ttgaatcata ttcaatacct
     1861 aaaatgacaa atacacatct tgatgaaagt aatattttat cacaatttta ttcaatgttg
     1921 cctgtaggta taattcgcta cgatttattt ggtgatatga ttattactta tatgaatgaa
     1981 gaaatgtttg atattatagg ttatacaaaa gaacagtttt ttggtgagat gggcggaaat
     2041 ttaagagcaa ttgttcatcc agatgattta gactttgttt ataaaaaaag tttggatatg
     2101 attgacacaa ataaaattga accattttta tatagattca taaaacgaga tggtcaaatt
     2161 gtcacagtta tgtatacaca atgtaacctt tctgcaattg atggaaggtc gattgcccag
     2221 ggtatgtatg tagatgtaaa taaaataaaa aatttaacaa aaatctagta caaagtattt
     2281 tattttggag aaattaatat gtttaaagaa atttttttaa gaacttttcc aggatttcta
     2341 attataagag attctaacta cagaattata tttataaatg ataatttaaa aaatttaatt
     2401 aaaagttata tgcaagataa tccacttgga atgactaata tagaaatagc taagaaactc
     2461 cctgataata ttgctaaatt ttttacggat tctcacaata ttcaattaga ttgggaaaaa
     2521 aattatcctt atgataaaat ttcaaattgg attttagagt ttaaaaaaga tactacaagc
     2581 tattggaatg ttttagaata taaagtagat gttgatgaaa aaacctacat aattactatg
     2641 gccaatgata taacaaaact ctatgaagaa aataagagaa atcttcacta ctcaattact
     2701 gacccattaa ctggagcata taatagaaaa tatttaaatg atagatttga catatttata
     2761 ggagattata ttgtactaat tgacttagat aatttcaaaa tgataaatga ctatgaaggt
     2821 cataatgtag gagacaagat tttatgtgat tttgtttcac ttttaaataa agaattaata
     2881 aattctactt ctattataag attaggagga gatgaattta ttgttatatt ctctagtgat
     2941 gttgacaaaa attatgttta ttcacaacta gaagccttaa gagaaaattt tttaaaagta
     3001 ttctctaagt ataagtatct ttcatttagt tatggtgttg atacagtaaa aagaaattta
     3061 aaattgacaa tagttgaatt ggataaaaaa atgtataaaa acaagaaaaa atttgataaa
     3121 aatgattatt aatattgtta ttttaaaata aattaaaatt atctttcttt ttttaaactt
     3181 gtacattagt ttataaatat gtatctatac aagatattga cattaagtac tgaagcatat
     3241 attgtttcag ttcttttttg ttaaaattaa cttatttaac aaagatatca tagtttaaca
     3301 aagcttttaa tttaaatata ttgatgtata atataattaa aatataatag caaaaagaaa
     3361 ggaggaatat catgagcata ctcctaaaaa aagcacccaa attagcaaaa catattataa
     3421 caagttttta tataaatcgg gatattgatg aagtattaaa atacctttgt gaaaatgtta
     3481 catggatcgg accaggagaa caggaatttc tcacttcttt taatgaaata aaaaattatt
     3541 tttatgcagg tcaagatgaa attccttctt gtgatataaa taatgatata tttgaaactg
     3601 taagtgaaga tgagaataga tgtatggtat taggaagata tactgttcga actaaagaaa
     3661 atactcaaat gattttagag gtaaatcaac gttgtacatt tgagataatt gaggatagag
     3721 gaaaattatt agtaaagcac atgcacatat caaaccctta tggtgaaatg caacttgatg
     3781 aatactttcc cactaaaatt ggaactcaaa gttatgatta tttgcaaaga ttactaaagg
     3841 aaaaaacaga agttattgaa atgattacaa ataatatcaa tggtggctta aaaggtagca
     3901 atgatgataa tacatactca tttttctatg tcaatgaagg attgcccaaa atattaggat
     3961 acacatatga tgagttcatg gaaatgagtg gtggttcagc agtgggtgct gtatatccac
     4021 cagacttacc taaagcacta gaagattgtg aacgatgttt tgcaaaagga cctacatatt
     4081 catctgaata tagaatccga aaaaaagatg gaacattaat gtgggtatta gattctggaa
     4141 tgaaatcatt aaatagtgat ggcatagtaa aaattaatag tattattact gacataaccc
     4201 aactaaaaaa catagaatct gaactaaaat tagaaagaga gcgatatcgt attgctttgc
     4261 aaaatattac agatatcatg tttgagtatg atattgaaaa cgataccctt ataaaatatc
     4321 aacgtgtaga aattgacaaa aaaattgaat tagaaaattt tgaaacaaaa aattactcca
     4381 aactattaga atctggtaaa attattcacc ttgatgatat tggaaaacta ctagaagtac
     4441 ttcatggaaa tcttcgtgaa acaattgaga taagacaagt aaattcatta actaaaaatg
     4501 aatggagatg gattcgtgtt caatgttcag ttatatatga tagtgaccat aaccctatca
     4561 aaacaatagg cgttttaaaa gacataactg aagataaatc taaattagaa agcttaatta
     4621 atcaggctca acgtgaccca ctaacacaat tatataatca aagagtatca caaaatctta
     4681 ttgaagagta tctatgtagt tctgattcca aaaataatga tgctctatta gttattgata
     4741 ttgatgattt taaaactgta aatgatactt ttgggcattt agagggaaat gaagttttag
     4801 ttgctgtatc aaaaatacta ttacataaca cacatgataa agacatagtt gctcgaattg
     4861 gtggagatga atttacaata tttataaaat cattaacaaa ggatttaata ataaaaatta
     4921 ctaatgatat tttaaatgat gcaagtaaaa taaaagtaaa ggacaatcat aaaataacat
     4981 taagtattgg tattgccttc actgatgatt caactaaatt atataaagat ttattttcta
     5041 aagctgataa agctctttat ctatcaaaag cagatggcaa aaattgttat agtacatacg
     5101 aataataaag ctatttatac gaccaagaat gaacctttaa atttaatttc atagtctaac
     5161 aatcaaagag ttgaagctaa tcttatagct agtcaactag ttcctagaaa aaatttaaac
     5221 aatatattta ttgatactgc tcatttttct aaagagcaaa tttatataaa aaattaaact
     5281 tttatgtaca tacagatact aatgataaac agttatcatt agtatcttct atcttaaaac
     5341 aaaatgataa tttatctata taaaaaagtg ctttgttgac agagttcact tttttatata
     5401 ggtacagaat ttaagtataa atacatgttt tattctatac attttagtta atgtaaaatt
     5461 tcttgattgt actctctaac ttttcaacat tatactattt atataccact tagttaatat
     5521 aaacccctta gctggttcta gtgctttttc tatgatttta gtcatattta cataccactt
     5581 agttaatata aaaccaattt agatgatgta tatgtgcaaa aggaagaaat aatttacata
     5641 ccacttagtt aatataaaac gctactaaac ttgatataca tgaccattat aataataaat
     5701 ttacatacca cttagttaat ataaaacttc cataaaaaca tccccttttt attcttcttc
     5761 cttatattta cataccactt agttaatata aaacagtctt tttttaatgc agagatgcaa
     5821 gaagttttat aatttacata ccacttactt aatataaaac tatcagtatt taagtaataa
     5881 tttaagtaat ataggattta cataccactt agttaatata aaacggtcac tacaacttat
     5941 acttccagtc taacgatttg aatttacata ccacttagtt aatataaaac atattttgga
     6001 tttattaata taaacataat taaaaaattt acataccact tagttaatat aaaaccccaa
     6061 aataaactgg gcattttcaa tacttacaca tatgcaactc tcttaaattt gcagtgaacc
     6121 atgagtagtg caaatgataa agcttatcat ataccctcaa caccttatat ttcaagcgtt
     6181 aagctctact ttgtaacaaa tatcgctcac tgcaaaacta tttacatttt tattatatca
     6241 taaatatatt atttttgaat atctatacca atttgtggta taataaaagc aagaagaact
     6301 acaatctatt tagacgtaga gtgaagttca aatactaatg tttattcttt ttgaacttga
     6361 tttttagttc aaaactaaag tcactcctgc ctgtgtgaac tatacccgct gttttataca
     6421 gttaaaacat gtaaaaatag ttataaagta ctagtgtaac tcattagtac tctttttatt
     6481 atattcatat aattaatatc tatattttaa agtttactat ctaaaaaaga gcacgtcaaa
     6541 taaaacccta gatatttaat ttttttagag atacttaaaa taaattatgc tctctctgta
     6601 cttaaatatt tcctaaattc aaatggagac atagaattta atctattttg atatctaaaa
     6661 ttattatagt agtatatata atcatctatt gctttaacta attattcata tgtatcaaat
     6721 ttccttaaat agtacatttc tacctttaaa attccccaaa atccttccat aggagcattg
     6781 tcaaggcaac gaccaactct tgtataatat atgtatatct aacaccatta agaaatatat
     6841 attttataat atatatttct tcatttaatg cacttagaaa agcaaagaaa atacagatta
     6901 gtacactttt tagagaaaaa taaaattaat acatctaaaa tattaaaaaa tactttagat
     6961 aatctaaaga cacatctcaa agtttttaac taaattataa aactaattac aaatgctatg
     7021 taacgataat aaataaaaaa tttacttcgc ttaagcgacg tgtcgttgaa atatttcatg
     7081 ttgccaactg gttcgtaagt tgataagaaa agaacactaa ttatttagag ttcttttctt
     7141 agctacaagt ggattataat acttttaaat ctgtgagaaa atcatatata ataatgatat
     7201 gaacaagtaa agaaaataca aaaatgacaa aattataaat aaaatattat aaaatcataa
     7261 ggtcataatt gttatattgt agaaacaaag taaagagaga gggtggagaa taaatgaatc
     7321 aaaaaaaaat aaagattagt attaaaatgg taattatagg tatatttgct gtaattattg
     7381 cttttgtatt atccagatta ttcgttgagt atattgatga attattaagg tctaattggc
     7441 aatatcagct atttgaaagt gagagttcat atatagtatt tgccaattgt attatgttct
     7501 cgaatatatt attagaaata tttttaatat atatttgtag aaaatttaga aaaatctaat
     7561 atggtcaacg tatttcgaat cgaatacttc atgattattt agtctattgt gctagttaaa
     7621 gtttaattcc catataaagt aaattgattt tagtaaaaca aatcacccct aagggttagt
     7681 ttatggataa gtcatccaaa tattaactct ttaatttttg ctatagattc atctttgctc
     7741 ataactttac ttataaaaaa tgaaatatta taagctagaa cttttattct aattctagtc
     7801 ataaatc
//
LOCUS       DAEPHU010000124         7555 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 01A10CD0081
            SAMN05941466-rid12468953.denovo.125, whole genome shotgun sequence.
ACCESSION   DAEPHU010000124 DAEPHU010000000
VERSION     DAEPHU010000124.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941466
            Sequence Read Archive: SRR6291087
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 7555)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7555)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068158.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 22:43:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,892
            CDSs (total)                      :: 3,805
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 87
            rRNAs                             :: 8, 1, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 55
            CDSs (without protein)            :: 55
            Pseudo Genes (ambiguous residues) :: 0 of 55
            Pseudo Genes (frameshifted)       :: 21 of 55
            Pseudo Genes (incomplete)         :: 28 of 55
            Pseudo Genes (internal stop)      :: 16 of 55
            Pseudo Genes (multiple problems)  :: 8 of 55
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7555
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941466-rid12468953.denovo.125"
                     /strain="01A10CD0081"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            <1..1291
                     /locus_tag="KR231_003555"
     CDS             <1..1291
                     /locus_tag="KR231_003555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906093.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="EAL domain-containing protein"
                     /protein_id="HBH0005882.1"
                     /translation="KHVQNYIISNEKENCVMACFDLCRLKLINDIYGYELGDEVLNNI
                     LSNLKNYFGKEAIYGKLKSDVFVLIIKLENREQKIPYLVNLIKNKIVILSQIDSFKMD
                     INIEASIGIYKFNNNEIDIKKAIDNADMARLKSKGLKHIEYVEFDNAMEEEIQSIMKI
                     ERDLFLAIKNKEFVIHYQPKVDSSTGNIIGSEALIRWLHPSLGMVGPNKFIPIAEKNG
                     LINNIGRWLIQEVFITINKWISEGINVLPVSINLSRVELYKNDLVDFFKLMFNTYNIP
                     KELIELEITETTALRDVKFISERLYEIKSLGMNISLDDFGVGNSNFINLKGIPLDIIK
                     IDRSLILDIVTNTKTKFMVKAIVNLSHDLNVTVICEGVEDMHQVKVLSELGCNFIQGY
                     VFFKPLDEMNYKKLLTDGSYINLKDTLLDKCMTVEEE"
     gene            1294..1692
                     /locus_tag="KR231_003556"
     CDS             1294..1692
                     /locus_tag="KR231_003556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426473.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rrf2 family transcriptional regulator"
                     /protein_id="HBH0005883.1"
                     /translation="MISEDVDYSIRIIRAIFNNGEDKPIDAKMILKSEDIPILTLYRL
                     LRKLCANNILTFNKEDGKTYMLNVSLDTISLRTIVEVIDGKIYINKCTRYVSNCSNCL
                     KGCKVNRELLEIEKEIYKLLSRKSIRQILE"
     gene            1732..3465
                     /locus_tag="KR231_003557"
     CDS             1732..3465
                     /locus_tag="KR231_003557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-6 DNA methylase"
                     /protein_id="HBH0005884.1"
                     /translation="MDDISQDNFLLSKEYENSLDVDTKKASGIYYTPKIIVDYIVKKT
                     LKNHDIIKNPYPRILDISCGCGNFLLEVYDILYDLFEENIYELKKKYDENYWTVDNIH
                     RHILNYCIYGADIDEKAISILKDSLTNKKVVNDLDESDIKINLFCCDSLKKKWRYKFD
                     YIVGNPPYIGHKKLEKKYKKFLLEKYSEVYKDKADLYFCFYKKIIDILKQGGIGSVIT
                     PRYFLESLSGKDLREYIKSNVNVQEIVDFLGANIFKNIGVSSCILTFDKKKTKETYID
                     VFKIKNEDICINKFETLEELLKSSKFEHFNINQRLLSDEWILVNKDDETFYNKIQEKC
                     KYSLEDIAISFQGIITGCDKAFILSKDDVKLNLVDDKFLKCWIKSKNINKYIVDKSEY
                     RLIYSNDIDNENTNKRILDEIIGLYKTKLENRRECKSGIRKWYELQWGREKLFFERKK
                     IMYPYKSNENRFAIDYDNNFSSADVYSFFIKEEYLDKFSYEYLVGILNSSVYDKYFKI
                     TAKKMSKNIYDYYPNKVMKIRIFRDNNYEEIENLSKQIISILLNKSIDKGKVEKLQIK
                     MDNLIMDSLGI"
     gene            3697..4908
                     /locus_tag="KR231_003558"
     CDS             3697..4908
                     /locus_tag="KR231_003558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="patatin-like phospholipase family protein"
                     /protein_id="HBH0005885.1"
                     /translation="MKGLVLEGGGTKGAYQIGAYKALRELGIEFQGVTGTSIGALNGA
                     YIIQNDIEVMEDIWLNYDYTHFMNIDRETYERFKNVDFTTKNLNAVFELINKARKNEG
                     IDISPLRQLMETTLNEDIIRKSKKDFGLVTVWWDKKINPYPLYIEDIPKGRLIDYLIA
                     SSSLPIFQTNMMDDKLYLDGMFCDNMPIGLLEDKGYEDVVVIRLIDDFIGKMNLNRHQ
                     NINIKTIIPSEYLGGSLNKDRDNVEKNIRLGYLDTMKAYERCTGIKYYFDVEYKYNEE
                     YCFDKFRSMSNETIQYICNLLNIKRDASLRTVMESVIPKLGEVLGLPKDFSYKDLFYC
                     IYEKKLEENNINRIKLYDFNKVIDVVNTNIDSNRNLASNFEVRPKISIKKNKNTKLLT
                     NCIIKDIKNQS"
     gene            5100..5360
                     /locus_tag="KR231_003559"
     CDS             5100..5360
                     /locus_tag="KR231_003559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HPr family phosphocarrier protein"
                     /protein_id="HBH0005886.1"
                     /translation="MEKVVSIKNASGLHARPAGMFVKKAAEFKSTVEVVAKDKTVNAK
                     SIMGIMSLGLAQGEELKLVVNGEDEEVALAAMVELVESGFGE"
     gene            5714..7426
                     /gene="ptsP"
                     /locus_tag="KR231_003560"
     CDS             5714..7426
                     /gene="ptsP"
                     /locus_tag="KR231_003560"
                     /EC_number="2.7.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate--protein phosphotransferase"
                     /protein_id="HBH0005887.1"
                     /translation="MAYKGIGASPGVALGKALVVEHSELVIEKKSIDNVEAEIAKLED
                     AVAVSKEELVKVKEKASEELGAEEAEIFEAHLLVLEDPELIGSAIDKIKTESVNAEYA
                     LNEIKEMFVSMFESMDNEYMKERAADIKDVTNRILRHILGIKVVDLSALSEEVVLIAH
                     DLTPSDTATMNKKMVLGFLTDIGGRTSHTAIMSRTLEIAAIVGLNDITSKVKDGDFVV
                     FNGDTGEVIVNPDEETINKYTELKAKYEDERKALQLLKGKPSVTLDGKHVELAGNIGT
                     PNDIEGLIKNDAEGVGLYRTEFLYMDRDSFPTEEIQYEAYKAVLEGMDGKPIVIRTLD
                     IGGDKELSYLSMEPEMNPFLGYRAIRLCLDRKDIFKTQLRALYRASVHGRLRIMFPMI
                     SSLEELLQAKEVVKEVLAELDSEGVAYAKDVEIGMMIEVPSAAVISDVLAKHVDFFSI
                     GTNDLIQYTCAVDRMNQKISYLYNQFNPAVLRLIKTVIDNAHKEGKWAGMCGESAGDQ
                     KMIPILLGMGLDEFSMSPISILPARKLITSVKESDMKKLADDVLNMGTAEEIKSYIEK
                     TFNI"
BASE COUNT         3137 a          675 c         1323 g         2420 t
ORIGIN      
        1 aaaacatgtt caaaattata ttatcagtaa tgaaaaagaa aactgtgtaa tggcttgttt
       61 tgatttatgt agactcaaac ttataaatga tatatatggt tatgagctag gggatgaagt
      121 gttaaataat attttaagta acttaaaaaa ttattttgga aaagaagcta tttatggaaa
      181 gttaaaaagt gatgtttttg tattaataat aaagcttgaa aatagggaac agaagattcc
      241 ttatttagta aatcttatta agaataaaat tgtgatacta agtcagattg acagttttaa
      301 aatggatata aatattgagg cttctattgg aatttataaa tttaacaata atgaaattga
      361 tataaaaaaa gctatagata atgctgatat ggcaaggctt aaatcaaaag gactaaagca
      421 catagagtat gtagaatttg ataatgctat ggaagaagaa atacaatcaa ttatgaaaat
      481 agagagagat ttattcttgg ctattaaaaa taaagagttt gtaattcact atcaacctaa
      541 agttgattca agtacaggta acattatagg ttcagaggca ttgataagat ggttgcaccc
      601 atcattaggc atggttggac caaataagtt tatacctata gctgaaaaaa atggtctgat
      661 aaacaatatt ggtagatggc taattcaaga agtttttatt accattaaca agtggatttc
      721 agaaggtata aatgtcttac cagtctcaat aaatctttct agagtagaac tatataaaaa
      781 tgatttagtt gattttttta aactgatgtt taatacatat aatattccaa aagaacttat
      841 agaattagaa attacagaaa cgacagcact aagagatgta aaatttataa gtgaaaggct
      901 ttatgagatt aaatctttag gtatgaatat atcattagat gattttggag taggtaattc
      961 aaattttatc aaccttaagg ggataccact agatattata aaaattgata ggtcacttat
     1021 attggatata gttacaaata caaaaacaaa gtttatggtg aaagcaattg ttaacctttc
     1081 acatgattta aacgtaactg ttatatgtga aggggtagag gatatgcatc aggtcaaagt
     1141 cttaagtgaa ctgggatgta atttcataca aggttatgta ttttttaaac ctttggatga
     1201 gatgaattat aaaaaacttc ttactgacgg aagttatata aatctgaaag atactctttt
     1261 agataaatgc atgacagttg aggaggagta aggatgattt cagaagatgt agattattca
     1321 ataagaatca taagagctat atttaataat ggagaagata aaccaataga tgctaaaatg
     1381 atattaaaaa gtgaagatat accaatacta acactataca gactgcttag aaagctttgt
     1441 gcaaacaata ttcttacttt taacaaagaa gatggcaaga catacatgtt aaatgtgtca
     1501 ttggatacaa taagtctaag aactattgta gaagtaattg atggaaaaat atatataaat
     1561 aaatgtacga gatatgtatc taattgcagt aattgcttaa aaggttgtaa agtaaatcgt
     1621 gaattgctag aaatagaaaa agaaatttat aaacttttat cgagaaaatc tataagacaa
     1681 atactagaat aaaaaatttt cagctatgat aataattgga ggttttcggt tatggatgat
     1741 atatctcaag ataattttct actgtctaaa gagtatgaga atagcttaga tgtagatact
     1801 aaaaaagcaa gtggaatata ttatactcct aaaataattg tagattatat tgtgaaaaaa
     1861 actttaaaaa atcacgatat aattaaaaat ccatatccac gaatacttga tatttcctgt
     1921 gggtgtggaa attttctttt agaagtatat gatattttat atgacttatt tgaggaaaat
     1981 atatatgaat tgaaaaagaa gtatgatgaa aattattgga ctgttgataa catacaccgt
     2041 catatattaa actattgtat atatggtgct gatattgatg aaaaagctat aagtatatta
     2101 aaagatagct taacaaataa aaaggtagta aatgatttag atgaatctga tataaagatt
     2161 aatctatttt gttgtgatag tcttaaaaag aaatggcgat ataagtttga ttacatagtg
     2221 ggtaatccac cctatattgg tcataaaaaa cttgaaaaga aatataaaaa atttctccta
     2281 gaaaaatata gtgaagttta taaggataaa gctgacttat atttttgttt ttataaaaag
     2341 attatagata ttttaaagca aggagggatt ggcagtgtta taactccaag atatttttta
     2401 gaaagtctat caggtaaaga tttaagagaa tatattaaat caaatgtcaa tgttcaagaa
     2461 atagtggatt ttttaggtgc aaatatattt aaaaatatag gggtatctag ttgtattcta
     2521 acttttgata agaaaaaaac aaaagagaca tatatagatg tatttaaaat caaaaatgag
     2581 gatatatgta taaataaatt tgaaacattg gaagaacttc taaagagtag caaatttgaa
     2641 cattttaata taaatcagag attgctatct gacgaatgga tacttgtaaa taaagatgat
     2701 gaaacttttt ataataagat acaagaaaaa tgtaaatata gcttggaaga tatagcaata
     2761 agttttcaag gaataattac agggtgtgat aaagcgttta ttttaagtaa agatgatgta
     2821 aagttgaacc ttgtagatga taaattttta aaatgttgga taaaaagtaa gaatataaat
     2881 aaatatatag tagataaaag tgaatatagg ctaatatact caaatgatat agataatgag
     2941 aatacaaata aaaggatact agatgaaatt atagggctat ataaaacaaa attagaaaac
     3001 agaagagaat gtaaaagtgg aataaggaaa tggtatgaac ttcaatgggg tagagaaaag
     3061 cttttctttg aaagaaaaaa gataatgtat ccttataaat caaatgaaaa tagatttgct
     3121 atagattatg ataataattt ttcaagtgca gacgtatatt ctttttttat aaaagaagag
     3181 tatttagata aattttcata tgaatatcta gttggaattt taaattccag tgtttatgat
     3241 aaatacttta aaataactgc taaaaaaatg agtaaaaata tatatgatta ctatcctaat
     3301 aaggttatga agataaggat ttttagggat aataattatg aagagataga gaatttatca
     3361 aagcaaataa tatcaatttt attaaataag tctatagata aaggaaaagt agaaaaattg
     3421 cagataaaaa tggataactt gataatggat tctttaggta tataagcagt tgtaagtatt
     3481 aaaaaattat aatcttttaa ttgtttattt aaatttagaa ataaaaagtt agccatataa
     3541 aaaatattaa aaatatatac ttttcaatat ttttttgata aaataagaat gaatttgtgc
     3601 aattttattt ttctccaata actaaaaata gttttttgaa ttaatatttg cttaagaata
     3661 aaaatcagaa acgtttttga tatagtaggt gataatatga aaggattagt tttagaaggt
     3721 ggaggaacaa aaggagccta ccaaataggt gcatataaag ctttaagaga gcttggtata
     3781 gagtttcaag gagtaactgg cacatcaatt ggtgctttaa atggagcata tataattcaa
     3841 aatgatattg aagtaatgga agatatttgg ttaaattatg actatactca ttttatgaat
     3901 attgatagag aaacctatga gaggtttaaa aatgtagatt tcactactaa aaatctcaat
     3961 gcagtgtttg agcttataaa taaagctaga aaaaatgaag gtatagatat aagcccatta
     4021 agacaattaa tggagacaac attaaatgaa gacataataa ggaaatcaaa aaaagacttt
     4081 ggacttgtta cggtctggtg ggataaaaaa attaatccat atccattgta tatcgaagat
     4141 atacctaaag gaagattgat tgattattta attgctagtt ccagtttgcc tatttttcaa
     4201 acgaacatga tggatgataa gttgtatctt gatggaatgt tttgtgataa catgccaata
     4261 ggactcttgg aagacaaagg ttatgaagat gttgttgtaa ttaggttgat tgatgatttt
     4321 attgggaaaa tgaatctaaa tcgacatcaa aatataaata taaaaactat aataccatca
     4381 gaatatctag gaggttctct taataaagat agagataatg tagaaaaaaa catccgacta
     4441 ggttacttag atactatgaa agcatatgaa agatgcactg gaattaagta ttattttgat
     4501 gtagagtata aatataatga agaatattgt tttgataaat ttagaagtat gagcaatgaa
     4561 acaatacaat atatctgtaa tttattgaat ataaaaagag atgcttcact tagaactgtt
     4621 atggaaagtg taataccaaa gcttggtgag gtgcttggat tgccaaagga tttttcatat
     4681 aaagatttgt tttactgtat atatgaaaag aaacttgaag aaaataatat aaacaggata
     4741 aaattatatg attttaacaa ggttatagat gttgtaaata caaatattga ttctaataga
     4801 aatttagctt ctaattttga agttagacct aaaattagta ttaaaaagaa caaaaacaca
     4861 aaattattga caaattgtat tataaaagac ataaaaaatc aaagttaaat aaaaaacaaa
     4921 aaaaatttgt aattatactc gaaaaaagtg tatattagta gtataatatt tttgtagcac
     4981 tagtgggaac aaaaaatgac cataggacaa aaaagtacca cttagtacca ttaaagtaaa
     5041 aaacaggaaa acaattttaa aaaatataaa atgtaaagtt tataggagga tttaaaaaaa
     5101 tggaaaaagt agttagtatc aaaaatgcaa gtggattaca tgctagacca gcaggaatgt
     5161 ttgttaagaa ggcagctgaa tttaaatcaa cagtagaggt tgtagcaaaa gacaaaactg
     5221 taaatgcaaa atcaataatg ggaataatga gtttaggttt agctcaagga gaagaattaa
     5281 agttagttgt aaatggagaa gatgaagaag tagctttagc tgcaatggtt gaattagttg
     5341 aaagtggatt tggagaatag atataataat tttttaaaaa tttgatattt agaatctaat
     5401 attacttaaa gtaaagtaac agagaagtat taaacatata cagaccaaca tttgtagata
     5461 tttaatttct ttgttacttt catgtttatt taatcagaag attaagacta ttgttaattg
     5521 ggtataaaaa tataaatatt ttagaaaatg aaataagata tttttaatca taaattcaga
     5581 gtaaaaatac agtaacaaat agtttataaa attttataaa aaattataag taaataaaac
     5641 tataaaaatg taaattattt atataaattt ataaagttta tgtgctagat gatatttttt
     5701 aggaggtaga gttatggctt acaaaggaat aggtgcttct cctggtgttg ctttagggaa
     5761 agcgttagta gttgaacata gtgaattagt aattgaaaaa aaatctatag ataatgttga
     5821 agctgaaatt gctaaattag aagatgcagt tgcagtttct aaagaagaat tagtaaaagt
     5881 taaggaaaag gcttctgaag aattaggagc agaggaagca gaaatatttg aagcacattt
     5941 attagtttta gaagacccag agttaattgg ttctgcaata gataaaatta aaactgaaag
     6001 tgtaaatgca gagtatgctt taaatgaaat aaaagagatg tttgttagca tgtttgagtc
     6061 tatggacaat gagtacatga aagaaagagc ggcagatata aaagatgtta caaatagaat
     6121 acttagacat atattaggaa ttaaagttgt tgatttatct gctttaagcg aagaagttgt
     6181 attaatagca catgatttaa ctccatcaga cacagcaact atgaataaaa aaatggtttt
     6241 aggattttta actgatatag gtggaagaac ttctcatact gctatcatgt ctagaacttt
     6301 agaaatagct gcaatcgttg gattaaatga tataacttca aaagttaagg atggagattt
     6361 tgtggttttc aatggagaca caggtgaagt aatcgtgaat cctgatgaag agactataaa
     6421 taaatatact gaattaaaag ctaagtatga agatgagaga aaagcattac agctattaaa
     6481 aggaaaacca tctgtaactt tagacggaaa acatgtggaa ttagctggta atataggaac
     6541 acctaacgat atagaaggtc taataaagaa tgatgctgaa ggtgttggtc tttatagaac
     6601 agaattttta tacatggata gagattcttt cccaacagaa gaaatacaat atgaagcata
     6661 caaagctgta ttagaaggaa tggatggaaa gcctatagtt ataagaacat tggatatagg
     6721 tggagataaa gaattaagtt atttaagtat ggaacctgaa atgaatccat tcttaggtta
     6781 cagagcaata agactttgcc tagatagaaa agatatattt aagactcaat taagagcttt
     6841 atatagagct agtgttcatg gaagattaag aatcatgttc ccaatgattt catctttaga
     6901 agagttgtta caagctaaag aagttgtaaa agaagtttta gcagaacttg attctgaagg
     6961 tgtggcttat gctaaagatg tagaaattgg tatgatgata gaagttccat ctgctgctgt
     7021 aatatctgat gtattggcta aacacgtaga tttcttctct ataggaacta atgatttaat
     7081 tcaatacact tgtgcagttg atagaatgaa tcaaaagata agctatcttt acaatcaatt
     7141 taatccagct gttttaagac ttataaagac tgttatagac aatgcacata aagaaggcaa
     7201 atgggcaggt atgtgtggag aatctgctgg agaccaaaaa atgataccaa tacttttagg
     7261 tatgggatta gacgagttct ctatgtctcc aatatcaata cttcctgcta gaaagttaat
     7321 aacttcagtt aaagagtcag atatgaaaaa attagctgat gatgtactta atatgggtac
     7381 tgctgaagaa ataaaaagct atatagaaaa gacttttaat atataattaa tgttatatag
     7441 ttactaaaat tcatttttct aaataacaaa attatatttt acgaataaaa aaactatagt
     7501 atatcatata tactatagtt tttttgttat ataaattacg tatcaaaatt tgtaa
//
LOCUS       DAEPHU010000125         7272 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 01A10CD0081
            SAMN05941466-rid12468953.denovo.126, whole genome shotgun sequence.
ACCESSION   DAEPHU010000125 DAEPHU010000000
VERSION     DAEPHU010000125.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941466
            Sequence Read Archive: SRR6291087
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 7272)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7272)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068158.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 22:43:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,892
            CDSs (total)                      :: 3,805
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 87
            rRNAs                             :: 8, 1, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 55
            CDSs (without protein)            :: 55
            Pseudo Genes (ambiguous residues) :: 0 of 55
            Pseudo Genes (frameshifted)       :: 21 of 55
            Pseudo Genes (incomplete)         :: 28 of 55
            Pseudo Genes (internal stop)      :: 16 of 55
            Pseudo Genes (multiple problems)  :: 8 of 55
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7272
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941466-rid12468953.denovo.126"
                     /strain="01A10CD0081"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            <1..440
                     /locus_tag="KR231_003561"
     CDS             <1..440
                     /locus_tag="KR231_003561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HBH0005888.1"
                     /translation="LNRNKARLKVARLQEHIANQRKDFLQKLSTKLIKENDIICIEDL
                     QVKNMIKNHKLSRLISDVSWSEFIRQLEYKANWYGRQIVKVGKFFASSQICNKCGYKN
                     EEVKNLNIREWICPSCNETHDRDINASINILKEGLRLITIQNK"
     gene            567..1736
                     /locus_tag="KR231_003562"
     CDS             567..1736
                     /locus_tag="KR231_003562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydantoinase/oxoprolinase family protein"
                     /protein_id="HBH0005889.1"
                     /translation="MNELCKDEVVEFCNRIKGKVESVAISGVFAPVNKQQEEEVAKWV
                     REILGDIPISLSNEIGNIGILERENGAILNSALSQVGKAVSLGFEKALKDLGIDAQIY
                     FSQNDGTLMNLEYTMKYPIFTIGCGITNSIRGASFLSKVKNAIVLDVGGTTSDLGVLY
                     NGFPRESSIPVTIGGVHTNFRMPDVLTIGLAGGTCVKGEKDNIKIGPESVGYRITEDA
                     IIFGGDTLTLSDVVTKLDMAFEDRKSNVENLDKEYCNEVYKKVILKLEDAVDQMKTSQ
                     DDVELVLTGGGSIIVPEKLKGISNVIRPPHYTAANAIGAALGQISGDVEKVYSLDKMS
                     REDAIEDAKKEAVNKALKAGAKEDTIEVLNIEDVPLAYLPGNALLIKVKVVGDLI"
     gene            complement(1899..2441)
                     /locus_tag="KR231_003563"
     CDS             complement(1899..2441)
                     /locus_tag="KR231_003563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1697 domain-containing protein"
                     /protein_id="HBH0005890.1"
                     /translation="MKSYIALLRGINISGKNKIIMSELKASFVELGYSEVSTYLNSGN
                     VVFLSDVDDSKVISNTIRLMIKKQFELEIPVFIISQEELKDILNNAPNWWGDNNKEIY
                     DNLIFMFPDLSYDEFYDEVGNPKEEYEKVYHYKNAIFWSFSRKDYKKTNWWSKTASSN
                     VSDKITIRTANTVRKIVGMR"
     gene            complement(2589..2873)
                     /locus_tag="KR231_003564"
     CDS             complement(2589..2873)
                     /locus_tag="KR231_003564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HBH0005891.1"
                     /translation="MAKNTKQTTVHIDETLLKEVKRIGINENKSISQIINESIIDYIL
                     VYRENEDKEKNEHDKNLNETINEFKKEEEKRMQAKSAARAIAEAKKRVLY"
     gene            complement(2936..3700)
                     /locus_tag="KR231_003565"
     CDS             complement(2936..3700)
                     /locus_tag="KR231_003565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-acyl-sn-glycerol-3-phosphate acyltransferase"
                     /protein_id="HBH0005892.1"
                     /translation="MNNYLKFATYQLIGFTSSIPRLIKIKKNPDKFSLKEKFEFMQKQ
                     AKKSLDIVNIELNIIGKETLPKEPLLFVVNHSSMLDSFILTASVERPIGCVIADEPVW
                     RNIPIFKEWAKLLRCVYVNRKNNREGIKSIAQASQNILTGQSMAVFPEGDLTWIKEPN
                     SLVSEFRSGALKIAYKAKCPIVPLVIKNSKDTYEGYQPIGKINSVPVEVEFLEPIYDH
                     IENPRLKSSVLGENIKNKMINTIENFRKSNKTFKEF"
     gene            complement(3982..4248)
                     /locus_tag="KR231_003566"
     CDS             complement(3982..4248)
                     /locus_tag="KR231_003566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3795 domain-containing protein"
                     /protein_id="HBH0005893.1"
                     /translation="MIESRCGILCYECGYKEKVNCKGCTEIEKPFWGEQCPVKSCCED
                     KNLTHCGLCDTFPCEMLNQFAYDKEQGDDGKRISQCKKWAVLAL"
     gene            complement(4290..5099)
                     /locus_tag="KR231_003567"
     CDS             complement(4290..5099)
                     /locus_tag="KR231_003567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBH0005894.1"
                     /translation="MNKIINNILNTCKQYTYILPHKLLRQYIAHYTISIPDTSIKENL
                     TLIPDASGCMIFKFDKKGIESAFWGATTKTTIVKNDIENVLFRVFVEFRPGGVYYLTG
                     LSQRESTDLKISLEDFNTLFSLEVNSIFERTSTIEELVEQLDMLFLSYLLKSNIVDMT
                     IPILENARKQNSIMSVKNISQISCYSERHLNRIFNNSLGMSVKSYLRLLRINLVLQEI
                     QNNKIPFATLAQDIGYYDQSHFINDFKSICGVNPTTYIKNLSDFYNEKYKF"
     gene            5412..5693
                     /locus_tag="KR231_003568"
     CDS             5412..5693
                     /locus_tag="KR231_003568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0005895.1"
                     /translation="MASKQTPRNNLEKFLRIRVLSHTGDKIHIKLPVNFAKRMIENNA
                     LDLFNGKDDVVDGKKVTEILVKAFDYDLTGEVVHLERKNGDIIKVSIVQ"
     gene            5957..6211
                     /locus_tag="KR231_003569"
     CDS             5957..6211
                     /locus_tag="KR231_003569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0005896.1"
                     /translation="MENKDFKLTICIFAFVIGVVVLFCCIGLGEFSAEHIIQQNGGIM
                     DTDQYNIYLDQSISQYRNFGSILALLGGIGILFDKYIRKY"
     gene            6256..6579
                     /locus_tag="KR231_003570"
     CDS             6256..6579
                     /locus_tag="KR231_003570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889674.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0005897.1"
                     /translation="MATEIFTVKITPLEAQKMIKENLDADLVFSDSYNLGDDKFILIT
                     TFEKYYARNNSDAGLIVVYENTTGKTVIKATSTGSAIGILKIDWGAGGNLLKRVKNIL
                     ADYII"
BASE COUNT         2708 a          862 c         1028 g         2674 t
ORIGIN      
        1 gtttaaatag aaataaagca agattaaaag ttgcaagact tcaagaacat atagctaatc
       61 aaagaaagga ttttctacaa aaactatcta ctaaattaat aaaagagaat gatatcattt
      121 gcatagaaga tttacaagta aagaatatga ttaaaaatca taaactatct cgcttaattt
      181 cagatgtatc atggtcagaa tttattcgtc aattagaata caaggctaat tggtatggta
      241 gacaaattgt aaaggtaggt aaattctttg caagttcaca aatatgcaat aaatgtgggt
      301 ataaaaacga ggaagttaag aacttaaata taagagaatg gatttgtcct agttgtaatg
      361 aaactcacga tagagatata aatgcaagta taaatatatt aaaagaagga ttaagactaa
      421 taacaattca aaataaataa cgtatgtaag aaccggagga actacgggga tagcctgtgg
      481 agaattagta agacatattt tagtatgcaa aattctgtga agcaggaacc ctgtgacttt
      541 agtcatggga ggttcagggt agaaagataa atgaactttg taaagatgaa gttgtagagt
      601 tttgcaatag aataaaaggt aaagtggaaa gtgttgcaat aagtggagta tttgctccag
      661 taaataaaca acaagaagaa gaagttgcaa aatgggttag agaaatttta ggggatattc
      721 ctatatcttt atcaaatgaa ataggtaata taggtatatt agaaagagaa aatggagcta
      781 ttttaaattc tgcattgtct caagtaggta aagctgtatc tttaggattt gaaaaagcac
      841 ttaaagactt aggtatagat gctcaaatat atttcagtca aaatgatgga acattaatga
      901 atttagagta tacaatgaaa tacccaattt ttacaattgg atgtggaata acaaattcta
      961 taagaggagc ttccttctta tcaaaagtaa aaaatgcaat agtattagat gttggtggaa
     1021 ctacaagcga cttgggtgta ctatataatg gattccctag agaatcatct attccagtta
     1081 caattggagg agtacataca aactttagaa tgccagatgt tttaactatt ggtcttgctg
     1141 gtggtacatg tgtaaaaggc gaaaaagata atataaagat aggtcctgaa agtgtgggat
     1201 atagaataac tgaagatgca ataatatttg gtggagacac tctaacttta tcagatgttg
     1261 ttacaaaatt agatatggcg tttgaagata gaaaaagcaa tgttgaaaac ttagataaag
     1321 agtattgtaa tgaggtatat aagaaggtta ttttaaaatt agaagatgct gtagaccaaa
     1381 tgaagactag tcaagatgat gttgaattgg ttttaactgg tggaggaagt ataattgttc
     1441 ctgaaaaact aaaaggcata agcaatgtta taagacctcc tcattatact gctgcaaatg
     1501 ctattggtgc agctttagga caaataagtg gagatgtaga aaaagtatac agtttagata
     1561 aaatgtcgag agaagatgcc atagaagatg caaaaaaaga ggctgtaaat aaagctctaa
     1621 aagctggtgc taaagaagat actatagaag tattaaatat agaagatgtt ccacttgcat
     1681 accttcctgg taatgcactt cttataaaag taaaagttgt tggtgattta atttaaagaa
     1741 taaatataag tatttccaga attatataaa tatttctgga ctcattttta aacttatttt
     1801 atcaataaaa acagcataac ttttgactat attcttataa gtttccgaac agccgatata
     1861 tacctatttt ttgaggttta tcggctgttt gttatctttt atcgcattcc aactattttt
     1921 cttaccgtat ttgctgtacg aattgtaatc ttatcactta catttgaact ggcagtcttt
     1981 gaccaccaat ttgtcttttt ataatcttta cgactaaaag accaaaagat agcattttta
     2041 taatgatata ctttttcata ctcttcttta ggatttccaa cctcatcata aaactcgtca
     2101 taagataagt caggaaacat aaaaataaga ttatcatata tttctttgtt gttatctccc
     2161 caccaattag gagcattatt tagtatatct tttaactctt cttgtgaaat aataaaaact
     2221 ggtatttcca attcaaactg tttttttatc attaatctta ttgtatttga gataaccttg
     2281 ctgtcatcta catcacttaa aaagacaaca ttaccactat taaggtatgt agaaacttct
     2341 gaataaccaa gttctacaaa gcttgctttt aattcagaca taattatctt gttcttacca
     2401 cttatattga tacctcttaa taatgcgata taacttttca tataataatt tcacctctaa
     2461 acattcacat ttttctatgt agtacaaact ggaatttgca tcttttataa ttctttcaaa
     2521 acttcttcat atgtaatttt tttaatataa aaaaatcggt gcttaatttg taccgatttt
     2581 tgtttttctt agtaaagaac tcgttttttt gcttctgcta tagctctagc agcacttttt
     2641 gcttgcattc ttttttcttc ttctttttta aattcattta ttgtttcatt tagattctta
     2701 tcatgttcat ttttttcttt atcttcgttt tctctgtata ctaatatata atctattatt
     2761 gattcgttta ttatttgaga tatactttta ttttcattaa ttcctattct cttaacttcc
     2821 ttaagtagag tctcatcaat atgaaccgtt gtttgctttg tattttttgc caccttaatc
     2881 acctcttaaa aaaaattcta acattaaaat tttttttagt caataaattt taatattaaa
     2941 attctttaaa tgttttattt gattttctaa aattttctat tgtatttatc atcttatttt
     3001 ttatattttc acctagtaca gaagacttta gtctaggatt ttcgatatgg tcataaattg
     3061 gttctaaaaa ttcgacttcg acaggaacag agttaatttt accaataggt tggtatcctt
     3121 cataagtatc ttttgaattt tttattacta gtggaacaat agggcatttt gctttatatg
     3181 ctatctttaa agctccactt ctaaactccg aaaccaatga atttggttct ttaatccatg
     3241 ttaaatctcc ttctggaaac actgccatac tttgacctgt aagtatattt tgagaggctt
     3301 gggctatact ctttataccc tcacgattgt tttttctgtt tacatataca catcttagta
     3361 attttgccca ttctttaaat ataggtatat ttctccaaac tggttcatct gcaattacac
     3421 atccaattgg tctttctaca cttgctgtta gtatgaagct gtcaagcata ctagaatgat
     3481 ttacaacaaa tagaagtggt tcttttggca gtgtttcctt accaattata ttaagctcta
     3541 tgttcactat atctaaagat tttttagctt gtttttgcat aaattcaaat ttttccttta
     3601 agctaaattt atcaggattc tttttaattt taataagcct aggtatagaa gatgtaaaac
     3661 ctataagttg atatgtagca aattttaagt aattattcat aaaattatct ccttaaaata
     3721 aaattattta ttactgtaaa gattttaaca taaaataaaa tttaagtcta ttttaattca
     3781 attttgtaac atatatttta aatagacaga gattgagatt ttatatttcc aattttagta
     3841 atcagatttt atcaataaat tactattcta ttaatttaat taaataacct ttaaatttaa
     3901 ttataaaaac tgttgcagaa atttctacaa cagtttaaaa aatttacctt acaaaaactt
     3961 attttataac aagagagtat attataaggc tagtacagcc cattttttgc actgagaaat
     4021 tcttttgcca tcatcacctt gttctttgtc atatgcaaat tgattaagca tttcacatgg
     4081 aaatgtatca catagaccac aatgtgtaag gtttttatct tcacaacaag attttacagg
     4141 acattgttca ccccaaaatg gtttctcaat ctctgtacaa cctttacaat tgactttttc
     4201 cttgtatcca cattcataac ataaaattcc acatcttgat tctatcattt taagtcactc
     4261 cttaaatata aattttatat gattgtatat caaaatttat acttttcatt gtaaaaatcg
     4321 gacaaatttt ttatataggt tgttggatta acaccacaaa tagatttaaa atcatttata
     4381 aaatgagatt ggtcgtaata accaatatct tgtgctaaag ttgcaaatgg tattttatta
     4441 ttttgtattt cttgtaatac aaggtttata cgaagtaatc taaggtatga tttaacactc
     4501 ataccaagag aattattaaa aattctattt aaatgtcgtt cactataaca actaatttgt
     4561 gaaatgtttt taacagacat aatagagttt tgttttctag cattttcaag aattggtata
     4621 gtcatatcta ctatatttga tttcaataag tatgataaga ataacatatc taattgttct
     4681 actaattctt ctatagtact tgttctttca aaaatggaat taacctctaa gctaaataat
     4741 gtgttaaaat cttcaagtga aatttttaaa tctgtagatt ctctttgaga aagacctgtc
     4801 aaataatata ctccacctgg gcgaaactca acgaatactc taaaaagtac attttctata
     4861 tcatttttta caatagtagt ttttgttgtg gctccccaga atgcgctttc tatacctttt
     4921 ttgtcaaatt taaatatcat acatccacta gcatcaggta ttaatgtaag attttcttta
     4981 atacttgtat ctggaataga tattgtatag tgtgctatat actgtcttaa caatttatgt
     5041 ggcaaaatat atgtatactg tttgcaggta tttaaaatgt tattgattat tttattcata
     5101 agtatatcct cctgatatat aaaaaataag tatactaatt tattttttat ataataaacc
     5161 agttttgttt taattgaaat attctaataa gatattttgt taaatttaga tacaataatt
     5221 gtaaagtaaa atctcaaaat atacaattat tataaatcat agatatttat taaataaata
     5281 tattaaagaa gaaggaatat aaaacaagat tagaaaataa tagtgttact ttcataataa
     5341 atacatataa agatattttt aagaataaaa tttattatta aataaaaaat aaaggagagt
     5401 gatttaatag tatggcatca aaacaaacac caagaaacaa tttagaaaag tttttaagaa
     5461 taagagtatt atcacataca ggcgataaaa tacatataaa gttacctgta aattttgcaa
     5521 agagaatgat tgagaataat gccttggatt tatttaatgg aaaagatgat gtagtagatg
     5581 gtaaaaaagt tactgaaata ttagttaagg catttgacta tgatttaact ggagaagtag
     5641 ttcacttgga gagaaaaaat ggagacatta ttaaagtttc aattgtacaa tagaattatt
     5701 ttatatgaat tttatttttg aatagttata aataattaga aatttgtaaa aaagtataat
     5761 atattattag taatggtaca gaatacacat ttataattta tagatgtgta ttttttgttt
     5821 aaaaaattta aatatataaa actataaagg ttacaatttt ggaaatagat gtaaatatat
     5881 gttgtattgt ataataagag taatataaaa tctagtaaaa ataatcaaat aaatttagct
     5941 tatgagaggg ataactatgg aaaataagga ttttaaatta acaatatgta tatttgcttt
     6001 tgtaattgga gtagtagtat tattctgttg tataggttta ggtgaattta gtgcagagca
     6061 tattattcaa caaaatggtg gaatcatgga tactgaccaa tataatattt atctagacca
     6121 atctatttct caatatagaa attttggttc tatattagct ctgttaggag gaatagggat
     6181 attgtttgat aaatatatca gaaaatacta gagattatgt tttgtctaaa ataaattctt
     6241 atgaggagat aaaaaatggc aacagaaata tttactgtaa aaattacacc cttagaggca
     6301 caaaaaatga taaaagaaaa tcttgatgca gatttagttt ttagtgattc ttataattta
     6361 ggagatgata aatttatact aattacaact tttgagaagt attatgcaag aaataatagt
     6421 gatgcaggat taatagtagt ttatgaaaat accacaggaa aaacagttat taaagctact
     6481 tcaacaggca gtgcaattgg aattttaaaa attgattggg gtgcaggtgg aaatttactt
     6541 aaaagagtaa aaaacatact tgctgattat attatttaat tattttatct aactgataat
     6601 atgtcaagaa aatctcgtaa aagaggttaa gaacattttt ataatatata gataaataag
     6661 aatttgaagg taaagttttt aaggtataaa gaaaaataat ataataaaac gaattggctt
     6721 tataattctt tataaggcaa agagcacatt tctttatata attgttggat attaaataat
     6781 atgtaaatac accatttaca tataaaaatt taattaatat gttaagagaa aatgaaatgg
     6841 aaattactaa aaaatatttt taaattggat aatggttgat attatgttta tacaaaaatc
     6901 atgtggaatt ttatatattt taaatatgat agtttaaaat tatgaaagaa tgataaattc
     6961 cagtttgtag ggtaattttg ataaataata ttaataagta tgagtaaaaa gtaggagcat
     7021 attaatataa tgtccctact tttttattat taaaattgtt tataatatca acactacatt
     7081 aaaacacaac ctaaatttga aaaacaaata gtttagaaat atgtactttt ttatctatta
     7141 tattctttta aatcgaattt tttcatctga acataaagtc tcaaatctat atgcgtctgt
     7201 catatcataa aaaccaaaaa atataaagcc atcacgagaa gtaaattcat attgtatatt
     7261 ttcaattttc aa
//
LOCUS       DAEPHU010000126         7242 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 01A10CD0081
            SAMN05941466-rid12468953.denovo.127, whole genome shotgun sequence.
ACCESSION   DAEPHU010000126 DAEPHU010000000
VERSION     DAEPHU010000126.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941466
            Sequence Read Archive: SRR6291087
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 7242)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7242)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068158.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 22:43:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,892
            CDSs (total)                      :: 3,805
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 87
            rRNAs                             :: 8, 1, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 55
            CDSs (without protein)            :: 55
            Pseudo Genes (ambiguous residues) :: 0 of 55
            Pseudo Genes (frameshifted)       :: 21 of 55
            Pseudo Genes (incomplete)         :: 28 of 55
            Pseudo Genes (internal stop)      :: 16 of 55
            Pseudo Genes (multiple problems)  :: 8 of 55
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7242
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941466-rid12468953.denovo.127"
                     /strain="01A10CD0081"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            246..2888
                     /gene="adhE"
                     /locus_tag="KR231_003571"
                     /gene_synonym="adhC"
     CDS             246..2888
                     /gene="adhE"
                     /locus_tag="KR231_003571"
                     /gene_synonym="adhC"
                     /EC_number="1.1.1.1"
                     /EC_number="1.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional acetaldehyde-CoA/alcohol
                     dehydrogenase"
                     /protein_id="HBH0005898.1"
                     /translation="MEKKEKVVEKSNVEVCSPEIVNSVETLRMRLEEIRLAQKEFATF
                     TQEQVDKIFLAASTAANQQRIPLAKMAVEETGMGIVEDKVIKNHFASEYIYNAYKDTK
                     TCGVIEKDEAFGFTRIAEPVGVLSAVIPTTNPTSTAIFKSLIALKTRNGIIFSPHPRA
                     KNCTIEAARVVHDAAVKAGAPKGLIGWVDVPSIELTNVVMAEADLILATGGPGMVKSA
                     YSSGKPAVGVGPGNVPAIIDESADIKMAVSSILVSKSFDNGMICASEQAVIVPEKIYE
                     EVKKEFKYRGAHFLNKEETEKVGKVVIIDGSLNARIVGQPAHVIAKMADVEVPKTARI
                     IIGEVESVELNEPFAHEKLSPVLAMYKSKSFEDAVAKAEKLVADGGYGHTSSLYADSI
                     NHPERVEKFVNAMKTCRVLVNTPSSQGGIGDLYNFKLAPSLTLGCGSWGGNSVSENVG
                     VKHLLNIKTVAERRENMLWFRAPEKVYFKKGCLGVAAREFKDVMDKKKAFIVTDSFLY
                     NNGYTKKLTDLLDEMGIKHTTFFDVAPDPTLACAREGAKAMADFQPDLIIAVGGGSAM
                     DAGKIMWVMYEHPEVDFQDLAMRFMDIRKRVYVFPKMGEKAYFAAIPTSAGTGSEVTP
                     FAVITDQDSGVKYPLADYELMPNMAIIDADMMMEMPPRLTAASGVDALTHALEAYVSM
                     LRTEPADGLALQAGKIIFEYLPRAYKNGKNDKEAREKMAMASTMAGMSFANAFLGICH
                     SLAHKLGAFHHVQHGVANALLINEVIKFNCAEAPNKMGAFSQYRYPDCIQRYAEFASF
                     AGIKGSTDQEKVDNLIKAIDELKAKVGLPKTIKEAGVEESKFLERLDAMVEQAFDDQC
                     TGANPRYPLMSELKEIYLKVYYGK"
     gene            complement(3248..3589)
                     /locus_tag="KR231_003572"
     CDS             complement(3248..3589)
                     /locus_tag="KR231_003572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0005899.1"
                     /translation="MLLILGNLNLNLDFDYRIIREENDDVDIFIDINYRSLDIDTDGS
                     NLFNSRIQFPFVRALILRLNKNNQCMTIHLLRDIDLFSAFANFEVDYTDSIINIKNQN
                     EKVILNKSIKK"
     gene            complement(3616..4287)
                     /locus_tag="KR231_003573"
     CDS             complement(3616..4287)
                     /locus_tag="KR231_003573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH0005900.1"
                     /translation="MPILETINLGKIYGKKETSVHALKNANLKINKGEFVAIIGPSGS
                     GKSTFLHLVGGLERPSNGTIKVDGKDICCLSDKELARYRRQKVGFVFQQYNLIPVLNV
                     KENIELPLKLDNKKIDKEYIDDLINLLGLNERKNHLPNQLSGGQQQRVAIARALSAKP
                     SIILADEPTGNLDSKTTEEVMDLLKSSIKKYNQTLIIITHNENIARKADRIISIIDGE
                     LKLTL"
     gene            complement(4299..6875)
                     /locus_tag="KR231_003574"
     CDS             complement(4299..6875)
                     /locus_tag="KR231_003574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HBH0005901.1"
                     /translation="MKDNLKIVLRYIKSYKARSLAIVVSIILATSLVVGIGTLSRSAQ
                     QADVDRLKRELGTDHVYFKNIKKNQLKSIKSSKDIKNLGITSYYASTDVNEKLPINIL
                     YANKNYLTSHSKLIKGRFPKASNEVVVEKWILNSMGLKPEINQNLTFKLYQKENPETF
                     KVVGILEDRFIEKKKGQCEIFSNLNESELNDFTTYIEFNEGSDINTNIDNIIKNAMLD
                     EKSIGRNSMLIESTMKNGTLDNSSKYVAIAMSLFAGIVIYSIYVISIYQRVQEYGVLR
                     AIGSTNFRIFKLMLYELFILALIAMPIGICIGMGGAQIFNRSVGNIQFEGNINVTPFV
                     IPDKIILLSIACTILIILIISFFTYLKIRRISPIDAIRKTFGADKNVTKVNYLISKLT
                     LNMSVTKSISAKNIFRNKKGFIIIVLSMSIGGIIVIKDNYKYSFLDVQNKSTQEQTYM
                     NADFILSNVYLNEIGNNTSFKDIKGFNDNQIDKIKNIDGIDKVKTASILNTRIEVNKI
                     NRLDYYEAINSTPYYKLNPLFIKNKTTGKYTLKQKLKGYNDEMIKSLEKYLVSGNINL
                     KKMKKENLAIVYVPEISKTQKYTKTFTPGEGTPAVDIKVGDTIKVKYPKGGMDTGLYE
                     SLKDNYEYLEYEFKVGAIISYPFADNGMYSGDDGVDVITSSEYLKKLTGVDKYNLVYA
                     DLNENANKKKINNLLGKIGSEVPGTTTVDMMVEKENSDKMTSRTMIYSYGIVAIMFII
                     SVLNIINNISYNLTSRTSEFGMLRAIGISERGFKNMILYEGILYGVLSSIITIVSGII
                     IQFKMYYMQGFVSYGLGFSIDYKIYILVILANIIVGILATYIPSRKINKISIVEAINI
                     TE"
BASE COUNT         2522 a         1029 c         1073 g         2618 t
ORIGIN      
        1 atgaaatata tctcatttag ataaaaaatt ttagtaaaag taaaaaaaat aatatatttg
       61 ttaaaaaata aattgacaaa atattcagaa aaaaacttct tgacctaaga gagtaaaata
      121 aataaaatct aaggtataga gatgaaatct ataaaattat tttaagtata agttaaaaat
      181 atagatgatg catttaagat taataaaaat tagagatgca taattatttt agggaggttt
      241 ttagtatgga gaaaaaagaa aaggtagtag aaaaatcaaa tgttgaagta tgtagtcctg
      301 aaattgtcaa cagtgttgaa acattaagaa tgagattaga agaaattaga ttggcacaaa
      361 aagaatttgc aacatttacg caagaacagg tagataagat tttcttagct gcttcaactg
      421 cagctaatca acaaagaata cctctagcaa aaatggcagt ggaagagact ggtatgggta
      481 ttgttgaaga taaggttata aaaaaccatt ttgcctcaga atatatctat aatgcttata
      541 aagatactaa aacttgtggt gtcatagaaa aagatgaagc atttggtttt acaagaattg
      601 ctgagccagt aggtgtttta tcagcagtta taccaacaac taatcctaca tcaactgcaa
      661 tattcaaatc cctaatagca ctaaaaacta gaaatggtat aattttctct cctcatccaa
      721 gagctaaaaa ctgtactata gaagcagcta gagttgtaca tgatgcagca gttaaggcag
      781 gagcaccaaa aggacttata ggttgggtag atgttccttc gattgaatta actaatgttg
      841 tcatggcaga ggcagacctt atattagcta ctggtggacc tggaatggtt aaatctgcat
      901 actcttcagg taaaccagct gtcggagttg ggcctggaaa tgtacctgca ataatagatg
      961 agagtgcaga tataaaaatg gctgtaagtt caatcttagt atcaaaatca ttcgataatg
     1021 gtatgatatg tgcttccgag caagctgtaa tagtaccaga aaaaatatat gaagaagtta
     1081 aaaaagaatt taaatatcgt ggagcacatt tcctaaataa agaagaaact gaaaaagtag
     1141 gaaaagtagt aataattgat ggttcattaa atgccagaat agttggacaa ccagcacatg
     1201 taatagccaa aatggcggat gtagaagttc caaaaacagc tagaataata attggtgaag
     1261 tagaatctgt tgaattaaat gaaccttttg cacatgaaaa actttctcct gtacttgcaa
     1321 tgtacaagtc taaaagtttt gaagatgcag ttgctaaagc agaaaaatta gttgcagatg
     1381 gaggctatgg tcatacatct tcattatatg cagactctat aaatcatcca gagagagtag
     1441 aaaagtttgt aaatgctatg aagacttgta gagtattagt taatactcca tcatcacaag
     1501 gtggtatagg tgatttatat aactttaaat tggcaccgtc tcttactctt ggttgtggtt
     1561 cttggggtgg aaactcagta tctgaaaacg ttggagtaaa acatttgctt aatatcaaga
     1621 cagtagctga aaggagagag aatatgcttt ggttcagagc accagaaaag gtttatttca
     1681 aaaaaggatg tttaggtgta gcagcaagag aatttaagga tgttatggat aaaaagaaag
     1741 catttatagt aacagattct ttcctatata ataatggata tactaagaaa ttaactgatt
     1801 tattagatga gatgggaatt aagcatacta cattctttga tgtagctcca gacccaacat
     1861 tagcttgtgc aagagaagga gctaaagcta tggctgattt ccaaccagat ttaataatag
     1921 ctgtaggtgg aggaagtgca atggatgctg gtaagataat gtgggtaatg tatgagcatc
     1981 cagaagtaga tttccaagac ttagctatga gatttatgga tataagaaaa agagtatatg
     2041 tatttcctaa gatgggtgaa aaagcgtatt ttgctgctat cccaacttca gcaggaactg
     2101 gttcagaagt aactccattt gcagttataa ctgaccaaga ttcaggtgta aagtacccat
     2161 tagcagatta tgaattaatg ccaaacatgg ctataattga tgctgatatg atgatggaga
     2221 tgccaccaag attaacagca gcatcaggtg ttgatgcttt aacacatgca ttagaagcat
     2281 atgtatctat gttaagaact gaaccagctg acggtctagc actacaagca ggtaaaataa
     2341 tatttgaata tttacctcgt gcatataaaa atggaaagaa tgataaagaa gcaagagaaa
     2401 aaatggcaat ggcatctact atggcaggaa tgtcttttgc aaatgccttc ttaggaatat
     2461 gtcactcttt agcacataaa ttaggtgcat tccaccatgt tcaacacggt gttgcaaatg
     2521 cattattaat aaatgaagta atcaagttca attgtgcaga agctccaaat aaaatgggtg
     2581 cattctcaca atacagatat cctgattgca tacaaagata tgctgaattt gcttcttttg
     2641 caggtattaa aggaagtaca gaccaagaaa aagtagataa tcttataaaa gcaatagatg
     2701 aactaaaggc aaaagtaggt cttcctaaga ctataaaaga ggctggagta gaagaatcta
     2761 aattcttaga aagattggat gctatggttg aacaagcttt tgatgaccaa tgtacaggtg
     2821 ctaatcctag atacccattg atgagtgaat taaaagagat atatctaaaa gtttattatg
     2881 gtaaataata tctattgtgc aacataggtt ctattgggtt tgtatataaa ttattagatt
     2941 tgaatataaa tagagtttta ttagagacac gtagaagtaa ctataaataa tagattataa
     3001 cttaaattct aaatggaaat gataaaaagt cagtaattta atggtaattt cgaatatgtg
     3061 tatttaatca attaacttta aaattagtcg gaaaattttt ttattacata taattttaaa
     3121 gcataatata taaaaaactt tatgaaaaaa ttataaaaat attcagaaaa ttctattgac
     3181 taatttattt atcatgatat aataagttta gaaaagaaaa aaattggggc ctattaaggc
     3241 ccccttacta ttttttgata gatttattta aaattacttt ctcattttga ttttttatat
     3301 ttattataga gtcagtataa tccacttcaa agttggcaaa agcagagaat aaatctatat
     3361 ctcttaacaa atgaattgtc atacattgat tgttcttatt tagccttaga atcaatgctc
     3421 ttacaaatgg aaattgtatt ctagaattaa ataagttaga accatcagta tctatatcta
     3481 agctacgata attaatatct ataaatatat ctacatcatc attttcttct cttattattc
     3541 tgtagtcaaa atccaagttt aaatttaaat tacctaaaat caataacatt taaatcctct
     3601 tttctataaa tagttttaga gtgttaattt aagctctcca tctattatag atataattct
     3661 atctgctttt ctagcaatat tttcattatg tgttattatt ataagggttt ggttatattt
     3721 ttttatagaa ctttttagta aatccatgac ttcttctgta gttttactgt ccaaatttcc
     3781 tgttggttca tctgctagga ttatacttgg ttttgcagat aaagcacgtg caatagcaac
     3841 tctttgctgt tgaccaccag ataattggtt gggaagatga tttttccttt cattaagacc
     3901 caataaattt ataaggtcat caatatattc tttatctatt tttttattgt ctaactttag
     3961 tggtaattct atattttcct ttacatttaa tacaggaatt aagttatact gttgaaagac
     4021 aaatcctacc ttttgtcttc tatatcttgc taattcttta tctgaaagac aacatatatc
     4081 tttaccatct acctttatag taccattact tggtctttca agaccaccta ctaaatgtag
     4141 aaatgtactt ttcccacttc cacttggtcc aattatagca acaaattcgc ctttatttat
     4201 ttttaaattt gcattcttta gtgcatgtac agatgtttcc tttttcccat aaatcttacc
     4261 taaattaata gtttccaata taggcataat tatccctcct attctgtaat gtttatagct
     4321 tcaactatac taattttatt tatctttctt gatggaatat atgtagctag aataccaaca
     4381 attatatttg ctaaaataac taggatatat attttgtaat ctattgaaaa tcccaatcca
     4441 tatgatacaa agccctgcat ataatacatt ttaaattgta ttataattcc tgacacgata
     4501 gtaattatac ttgagagtac accatataat attccttcat aaagtatcat atttttaaag
     4561 cctctctcag agataccaat agctcttaac attccaaatt cactagttct tgaagttaag
     4621 ttataactta tgttgtttat tatgttaagt acactgatta tgaacattat tgctactata
     4681 ccataactat aaatcatagt tctagatgtc atcttatcag aattttcttt ttctaccatc
     4741 atatctactg ttgtagttcc aggaacttca cttccaattt tacctaaaag gttatttatt
     4801 tttttcttgt ttgcattttc attaaggtct gcataaacta agttatactt atctacacca
     4861 gttaattttt ttaggtattc gctactcgtt attacatcta caccatcatc tccagagtac
     4921 ataccattat ctgcaaaagg ataacttata atagctccaa ctttaaattc atattctaag
     4981 tattcataat tatcttttag actttcataa agccctgtat ccatcccacc ctttggatat
     5041 ttgactttta tagtatcacc tacttttata tctacagctg gtgttccttc accaggagta
     5101 aaagtctttg tgtatttctg tgttttagaa atttctggta catatacaat agctaaattt
     5161 tcttttttca tttttttcaa gtttatattt ccacttacta agtatttttc taatgacttt
     5221 atcatctcat cattataacc ttttagcttt tgctttagtg tatatttgcc agtagtctta
     5281 ttttttatga acagaggatt tagcttataa taaggagttg aatttatagc ttcgtagtaa
     5341 tctaatctat ttattttatt tacctctatt cttgtgttta agatactagc agttttgact
     5401 ttgtcaattc catctatatt ttttatttta tctatctgat tatcattaaa cccttttata
     5461 tctttaaaag aagtattgtt accaatttca ttgagataaa catttgatag aataaaatct
     5521 gcattcatat atgtttgttc ttgagtagat ttgttttgca catctaaaaa agaatattta
     5581 taattgtctt ttatgacgat tatacctcct atactcatag ataatacaat tataatgaac
     5641 ccctttttat ttctaaagat gtttttcgca gatatagatt ttgttactga catatttaaa
     5701 gttaattttg atattaaata attaactttg gttacatttt tatcagctcc aaaagttttt
     5761 ctgatagcat caataggaga aattcttctt atttttaagt atgtaaagaa acttataatt
     5821 agtattatta gtattgtaca tgcaattgat aagagaatta ttttatctgg aataacaaaa
     5881 ggtgtaacat ttatatttcc ttcaaattga atatttccta cagacctatt aaatatttgt
     5941 gcacctccca tacctataca tatacctata ggcattgcta ttagagcaag tatgaaaagt
     6001 tcataaagca taagtttgaa aatcctaaag ttggtggaac caatagctct taagacgcca
     6061 tattcctgta ctctttggta tattgatata acatagatac tatatattac aataccagca
     6121 aatagactca tagcaattgc aacgtattta cttgaattat ctaaagtacc gtttttcata
     6181 gtagattcta taagcattga gtttcttcct atacttttct catctaacat agcatttttt
     6241 attatattgt ctatgtttgt atttatatca ctgccttcat taaattcaat ataagttgta
     6301 aaatcattca gttctgattc attgagatta gaaaaaattt cacattgtcc cttttttttc
     6361 tctataaatc tatcttcaag gattccaaca actttaaaag tttctggatt ttctttttga
     6421 tataatttaa aagtaaggtt ttgatttatc tctggtttta agcccatact atttaaaatc
     6481 catttctcga ctaccacctc attgctagct tttggaaatc gaccttttat aagtttagaa
     6541 tgactagtca aataattttt atttgcatat agtatgttta taggtaattt ttcattaaca
     6601 tctgtagacg catagtaaga tgttataccc agatttttaa tatctttgct agattttatg
     6661 gactttaatt gatttttctt tatattttta aagtatacat ggtcagttcc aagctctctt
     6721 ttcaatctat ctacatctgc ttgctgagca cttcttgaga gggtaccaat accaacaacg
     6781 agtgatgtag caagaattat actcacaaca attgctaaag acctagcttt ataacttttt
     6841 atatacctta gtactatttt caaattatct ttcatattta ccacttcctt tcttaactaa
     6901 atcaattata tatttatcta aaatatatag caaagtaagt attttcaagt tttaagtagt
     6961 taattgtaca aattcatctg tatttttaca agtttaatta atctatatgt aaattttaac
     7021 tttttacata atttttttaa aatgatataa tccctatata aattgtagag gggagggaaa
     7081 tcatggctaa caattttgta tttcctatag taatactaac tttgtttata tttagcaatc
     7141 ttataatgaa taagtataaa ttttacaaag aattagacat attaaaaaga ggcatattaa
     7201 cattttttat atcgtgtttt gcattgattt tatttatgga gg
//
LOCUS       DAEPHU010000127         7185 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 01A10CD0081
            SAMN05941466-rid12468953.denovo.128, whole genome shotgun sequence.
ACCESSION   DAEPHU010000127 DAEPHU010000000
VERSION     DAEPHU010000127.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941466
            Sequence Read Archive: SRR6291087
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 7185)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7185)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068158.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 22:43:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,892
            CDSs (total)                      :: 3,805
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 87
            rRNAs                             :: 8, 1, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 55
            CDSs (without protein)            :: 55
            Pseudo Genes (ambiguous residues) :: 0 of 55
            Pseudo Genes (frameshifted)       :: 21 of 55
            Pseudo Genes (incomplete)         :: 28 of 55
            Pseudo Genes (internal stop)      :: 16 of 55
            Pseudo Genes (multiple problems)  :: 8 of 55
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7185
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941466-rid12468953.denovo.128"
                     /strain="01A10CD0081"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            complement(98..649)
                     /locus_tag="KR231_003575"
     CDS             complement(98..649)
                     /locus_tag="KR231_003575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan transporter"
                     /protein_id="HBH0005902.1"
                     /translation="MKTNTKKLTLNAILLAMGLLIHQITPAIGLPMKPDVPLAMLFVI
                     LVLNRDDYKTCLIAGIVTGIFTALTSSFPGGQIPNVIDKTLTANIVFLLMNISYNMPF
                     IKKLAKKTQDTVVVAIIMPIGTLVSGTIFLLAAQAIVGLPGASFTALFLAVVLPAVLI
                     NLVAGIFLFKIVSLSIRRVSYQA"
     misc_binding    complement(800..1063)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(1498..1896)
                     /locus_tag="KR231_003576"
     CDS             complement(1498..1896)
                     /locus_tag="KR231_003576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0005903.1"
                     /translation="MNKKKKLIGIAISFLLIISIINPLQVEAEAIIESSVYISSIKEN
                     YTYDNTKFKTIKSKSRHKSRKYNKSKVKLKKRSIRTKKYGYQTINKYKRQNARRHNIL
                     TKLILFIIVIFLVIVLVVLIFIKRKKKKFY"
     gene            complement(2252..2737)
                     /locus_tag="KR231_003577"
     CDS             complement(2252..2737)
                     /locus_tag="KR231_003577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889961.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SH3 domain-containing protein"
                     /protein_id="HBH0005904.1"
                     /translation="MISELMLKNFRKSSINFKTKIKLNLREKPDINSLKLKSIPEGKI
                     VKLKCVDGIWAEVESNYDKGWLLYKYLERLSNAKNNSNDTIKNRKKNYIGNIRTNGLS
                     LELRNDRTLESKVITTIPDGFKVEVCYSVGKWARVNINKNEKRYSGYVYNQYIEEHLS
                     L"
     regulatory      complement(2820..2913)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01051"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="cyclic di-GMP riboswitch class I; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="cyclic di-GMP"
                     /db_xref="RFAM:RF01051"
     gene            complement(3267..3650)
                     /locus_tag="KR231_003578"
                     /pseudo
     CDS             complement(3267..3650)
                     /locus_tag="KR231_003578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431032.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
     regulatory      3876..3973
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01051"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="cyclic di-GMP riboswitch class I; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="cyclic di-GMP"
                     /db_xref="RFAM:RF01051"
     gene            4028..4204
                     /locus_tag="KR231_003579"
     CDS             4028..4204
                     /locus_tag="KR231_003579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0005905.1"
                     /translation="MFGNKMDKCTHVLTAYISSSYDYCNFLDTQLDDFILEYGENVVE
                     SCLHQVMVLVSKYN"
     gene            4430..4630
                     /locus_tag="KR231_003580"
     CDS             4430..4630
                     /locus_tag="KR231_003580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003723180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HBH0005906.1"
                     /translation="MNNGIVKWFNNEKGFGFISMEGRDDVFAHFSAIQTSGFKSLEEG
                     QQVSFDIVKGARGPQAENITIL"
     gene            complement(4794..5006)
                     /locus_tag="KR231_003581"
     CDS             complement(4794..5006)
                     /locus_tag="KR231_003581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0005907.1"
                     /translation="MVCKIFITLKTILPKTQIIVTTHSPHILQIDSKEEMIVLDMAES
                     DNVYKKELKLGEYGVLGWTNEGLYLH"
     gene            5381..5563
                     /locus_tag="KR231_003582"
     CDS             5381..5563
                     /locus_tag="KR231_003582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="integrase"
                     /protein_id="HBH0005908.1"
                     /translation="MFKFYNNATLMFLPGTNIKTISERLGHADIKITMNSYSQFLEEM
                     DREAFENLSKILFIVF"
     gene            5634..6479
                     /locus_tag="KR231_003583"
     CDS             5634..6479
                     /locus_tag="KR231_003583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0005909.1"
                     /translation="MNIIKSITLLLTLLIVILMTGCSPRESASEVAKKYIDKMNSGDY
                     ETAYSLLSKDSKKKISIENLEEFQNILVSTKRIISYKIGKEKIIKKYKHDGKEYKNVV
                     KLEETFNIKNLLYKKDDSLKVNRYFVVENNKYKLLLYESFKKEFGINSMDLAQLKLND
                     FGLKYFKEVDLILKKAIAINPTDSKLYYAQACNYMNFDGFPGYSDTTYNALDSINKSL
                     KYLDKNDSDYKKNASNIYNLKGVILMFHKRFDEAQQYLNKALYFNKDNKDPKYNLNTI
                     KKHLN"
     gene            complement(6703..6867)
                     /locus_tag="KR231_003584"
     CDS             complement(6703..6867)
                     /locus_tag="KR231_003584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0005910.1"
                     /translation="MFGKPKESVRFLDFNDVAEKFGEKKAVAIFDAIAGKKSKEHIIK
                     DIEKLVKNEV"
BASE COUNT         2590 a          965 c          740 g         2890 t
ORIGIN      
        1 tctttaaaca acataagaat aaaatagtta taatctactt tattcttatg ttatttagtt
       61 attataatgc tttataaagt aaaatattat ttcgtgttta agcttgataa ctaactcttc
      121 ttattgatag actaacaatc ttgaataaaa atattcctgc aactagattt attaaaacag
      181 ctggtaatac tactgctaag aataaagctg taaatgaagc ccctggaaga ccaactatag
      241 cttgagctgc taataaaaag atagttccac ttacaagagt tcctattggc attattattg
      301 caactactac agtatcttgt gttttcttag ctaatttttt tataaaaggc atattataac
      361 taatattcat taataaaaat actatatttg ctgtaagagt tttatctatt acattaggaa
      421 tttgacctcc cggaaaactt gatgtaagtg ctgtaaatat tcctgttact atacccgcta
      481 tcaaacaagt tttataatca tctctattta aaaccaatat tacaaataac attgctagtg
      541 gtacatctgg cttcattggt aatcctatag ctggtgtgat ttgatgtatt aataatccca
      601 tcgctaaaag tattgcattt aaagttaatt tttttgtatt tgttttcatt ttttgtactt
      661 cctcctattt ttttaatttt caatttattt ttttgccaac ctactatatc atcatcttta
      721 gcttttgaaa ttcataacat ctttctcacc accttctatc ttttaaattt tcagtaaaat
      781 aaaaaactcc gtcctaaact aataggacgg agattatccg cgttgccacc taaattatat
      841 aaaaattaat ataaaattca attttcatac atctcattat caggtactta cataccttat
      901 tcgctataac gtgcgactga cgataaagtc tactctcaaa actatgattt caatttattc
      961 ctctaagggc cattcatcaa attttttctt gctaagattc caccatcctc agctctctat
     1021 actgaaccta aatttaacta ctcttccttg tcataggatt taatttattg tattgaattt
     1081 tgttttaaaa taataatatt cttttttcta aaaaatgtca ataccttttt ataaaaaata
     1141 tattttgtaa tctatttttt ataaaaaaag taaattatac tatacatttc ttttcatata
     1201 caaaattcta tgaataatta ctttaatggt ctaatagtct gctctttggc tctaattctt
     1261 cttatattaa ttttgtgaat aactgttgat gtaattttat attttgattc atgaggaatt
     1321 aaattcttca aagttaatta agtacattta tcaataaatt tacttaatta accatcattt
     1381 aatactcatt cctgtattta tatgcctcct ttgaaacaga atattactcc attttaatta
     1441 catcatatta ttaaatagat accaatgatt aaaaaaatga tattctttta attattttta
     1501 gtaaaatttt ttcttctttc ttttaataaa tattagcact actaaaacta taaccaaaaa
     1561 tatgactatt atgaacaata ttaattttgt taggatatta tgtcttcttg cgttttgtct
     1621 tttatattta tttatagttt gatatccata ctttttagtt cttatacttc gttttttcaa
     1681 ctttacttta cttttattat atttcctact tttatgtcta cttttagatt taatagtttt
     1741 aaatttagta ttatcatatg tataattctc ttttattgaa gaaatgtata cactagactc
     1801 aataatagct tctgcttcta cttgtaatgg atttataatg ctgattataa gtagaaaaga
     1861 tatagctatc ccaatcaatt ttttcttctt attcatattt tccccctcat aaaaattttt
     1921 aactagttca ttataatata tatataacta aaaattacaa attttttcaa gtttcttata
     1981 tatcttatta tctttaatat tatttttatt atcataactt ttactttttt taagattttt
     2041 caaagtagta ttaatttatg atacttggtg tataaagtat aagttaaatc tactttcaat
     2101 taaatttacc atttataatt actttataat aaaaataaat tagttaattt attctcttta
     2161 gttctgttat aatgtttcta caaaaaagaa tcccattaat gggattcttt tttgcgattt
     2221 attaatatat ttaaagcttg ctagtatcgt attataaact taaatgctct tctatgtatt
     2281 gattatatac atatccagaa tatcgttttt catttttatt gatattaact cttgcccatt
     2341 ttccaacgct ataacatact tcaactttaa aaccatcagg gattgtagtt ataactttag
     2401 attctaatgt tctatcattt ctaagttcta aacttaatcc atttgttctt atatttccta
     2461 tgtaattctt ttttctattt tttattgtat cattactatt gtttttagca ttacttaatc
     2521 tttctaaata tttataaagt aaccaacctt tgtcataatt actctcaact tctgcccata
     2581 ttccatctac acactttaac ttaacaattt taccttctgg tatacttttt aatttcaaac
     2641 tatttatgtc tggtttttct cttaaattca atttaatttt agtcttaaaa ttgatgctag
     2701 atttgcgaaa attttttaac attaattcag atatcatctt aagccctcct cttgccaaat
     2761 attaagttat taaaatatat aactctaaaa atacttttaa caaaaagaat tattatcttt
     2821 ttggcaactg gctgacatga cctttattac ataaagattt tagtccctat agttttgcgt
     2881 cattagattt atctaatatt gcctatatct gaataataac ataatttgaa caattaaaaa
     2941 ataatattac ctcaaatttt atattattta aatataaatt aaatttttaa ttaataataa
     3001 tcaaaaaata tctttatatt tattcaatta ctgttcttta tagtcaatat aaaagacagt
     3061 aatttatcta tagtgttact tatattttat atatatggct atttttcaac attttacaat
     3121 atataacatt tattttttta acttttgtca gtaaaatgtc agcaaaacac tttatccaca
     3181 atttttatat aagttttcca caacttatca ccaatattat ccacataaaa aaggtagcac
     3241 ttatattatt agctaccttt tatttattaa tctttatatt tccagctttt tatccaactt
     3301 cctatttcta ttattttttc ttcagttatt tcttctccat catgtaattt tgaaattaat
     3361 tctgataaag gattgttatg taaacctcta aaaactcttt ttccctctat tttgagatat
     3421 tctctctctt ttattaatac tgtatagtgt acatgcctcc caattctcta tgatattaaa
     3481 aaaccttttt tggttaatct agctaaaagt ataattgtag ttgtatgctt ccaaccatat
     3541 gttttttcta tttcatctgc aacatctttt gatattacag ttttataacc agtatgccat
     3601 atgcatttca taatttttaa ttctgtatct ggtaattttt tatttagcat aatatattcc
     3661 ttctttcaat ttatgtcact tcttcaaatt tatctagctt aaattataat aggagctttt
     3721 tagaacaaaa actatattta atttttacca ggtactctac gtgtttagtc tgtttttaag
     3781 tgtaaaataa tgttcatatc tataaattta tttaactttc aaacaatcct gttgaataat
     3841 aactaattct attgtattat tttagttgta gaataaaact aaatcggcaa aactagagaa
     3901 atttagtgac gcaaagctat agggactaag acttatataa atatcttatg agttatgtca
     3961 gccagttgcc aaagagatag tgttcttttt gtttttatga aagtttttta gggggataat
     4021 aatttatatg tttggaaata aaatggataa atgtacacat gtattgactg cttatattag
     4081 cagttcgtat gattattgta attttttaga tacacagtta gatgatttta tattagagta
     4141 cggagaaaat gtagtagagt cttgtttaca ccaagtaatg gtattggtaa gtaagtataa
     4201 ttagatagac attgatttct agaaaaccct ttttagtttt atctacattt atattaatat
     4261 atagcaatgt aaaacgttta aatatatttt taatattaag aataattaaa atgttaacta
     4321 aaaaatataa ttaagtagac atttctatta atctatgata caatagtatt tgtggtaata
     4381 cacaattaaa tcaagtatat cttgatatag gttaatagga gtatttttaa tgaataatgg
     4441 aatagtgaaa tggtttaata atgaaaaagg attcggtttt atatcaatgg aaggtagaga
     4501 tgatgtgttt gctcatttct cagctataca aacttcagga tttaaatcat tagaagaagg
     4561 tcaacaagta agctttgata tagttaaagg tgctagaggt cctcaagcag aaaatataac
     4621 tatattataa tatatagatt tttcgggaaa gactcttttt agagtctttt tttattgtta
     4681 atatatgtaa gataatcatt ggtgaagtaa ataaggtata ttgagtaatg ttcttgatag
     4741 tttatatgct aatgaatttc aaaaaaataa gcactcctat aaaaagagtg ctcttaatgt
     4801 aaatataaac cttcattggt ccagcctaat accccgtatt ctccaagttt taactctttt
     4861 ttatatacat tatcactttc agccatatct aacacaatca tttcttcttt agaatcaatt
     4921 tgtaaaatat gaggactgtg tgttgtgaca attatttgtg tttttgggag aattgttttt
     4981 aatgtaataa aaattttaca taccacatag ttgatataaa acttaagact agcagactca
     5041 taagcaatta gttgcctctc tttacatacc acatagttga tataaaacct agaggctctc
     5101 agagaagtta taagatgttt agtaacttta cataccacat agttgatata aaactccaaa
     5161 ataaacttag catctccaat gtttacacat atacaatgct cttaaaattg cagtgaacgc
     5221 gcaatattgc aattgataat acttatcata tattctcaat accttatatt tcaactgcta
     5281 aacctcaatt tatcacaaat atcgctcact gcaaaatttc tatattttta ttatatcata
     5341 gcatataatt aatattttca attaattttt acatttaatt atgtttaaat tctataataa
     5401 tgcaacttta atgtttcttc ctggaactaa tataaaaact atttcagaaa gattaggtca
     5461 tgcagatata aaaataacta tgaatagcta ctctcagttt ttagaagaga tggacagaga
     5521 agcatttgaa aatttgagca aaatactatt tattgtattt taaagaagat gacttattca
     5581 atatttgatg ctagaatata attaataaaa atttaattat aggtgattgt attatgaata
     5641 ttattaaaag cataacttta ctcttaacat tattaattgt gatattaatg acaggctgtt
     5701 ccccaagaga aagtgctagt gaagttgcaa aaaaatatat tgataagatg aactctggtg
     5761 actatgaaac agcatatagt ttattaagta aagatagtaa aaaaaaaatt agtatagaaa
     5821 atcttgaaga atttcaaaat attttagtta gtacaaaaag aataattagt tataaaatag
     5881 gtaaagaaaa aatcataaaa aaatataaac atgatggaaa agaatataaa aatgttgtta
     5941 aattagaaga aacttttaat ataaaaaacc ttctttataa aaaagatgat tctctaaaag
     6001 taaatagata ttttgtagtt gaaaataaca aatacaagct attattgtat gaaagtttca
     6061 aaaaagaatt tggtattaat agtatggacc ttgctcaact taagcttaat gattttggac
     6121 taaaatactt taaagaagtt gaccttatac taaaaaaagc tattgctatt aatcctactg
     6181 attcaaagct ttattatgcc caagcatgta attatatgaa ttttgatgga tttcctggtt
     6241 attcagatac aacatataat gctttagatt caattaataa atctttaaag tatttagata
     6301 aaaatgattc tgactacaaa aaaaatgcaa gtaatatata taacttaaaa ggagttattc
     6361 ttatgtttca caaaagattt gatgaagcac aacaatattt aaataaagcc ttatacttta
     6421 acaaagataa taaagaccca aaatataatc taaatacaat aaaaaaacat ctaaactaga
     6481 tatttaattt ttgaatttat aaaatatttt tttatgtata attcagcact gaatcataat
     6541 ctctactaaa ctaattacaa gtttaaatta taaagactta tttctatata aatattactc
     6601 tataacaata agtttcttat ttaaatttta aaatattatc taaaaatcat aaaaaagaag
     6661 gtataaagag ctaccctcaa gctcaatata ccttataaat atctaaactt cattttttac
     6721 taatttttct atatctttga taatatgttc tttagatttt tttccagcta tggcatcaaa
     6781 aattgcaaca gcctttttct ctccaaactt ttctgctaca tcattaaagt ctaaaaatct
     6841 aacactttct tttggtttac caaacatata acacctctca tacattttta tatatttatt
     6901 ataacttcta tagacttatt tttcaccaat aaacgttaga caaattagtc cctttatttt
     6961 tttaaactag ctttaccttc aaaattctta acaaaaacag tttattctac tctataaata
     7021 aaaatagaca atttaatttg taggaaactg ataatagaat acagtaaata aaactttgtt
     7081 taatctatct gaaaaagtta tctattaaaa ctgctatgaa tttataaaga atattctagt
     7141 tcataaaaat acaaatatgt aaatataatc accttaatat tcaat
//
LOCUS       DAEPHU010000128         6992 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 01A10CD0081
            SAMN05941466-rid12468953.denovo.129, whole genome shotgun sequence.
ACCESSION   DAEPHU010000128 DAEPHU010000000
VERSION     DAEPHU010000128.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941466
            Sequence Read Archive: SRR6291087
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 6992)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6992)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068158.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 22:43:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,892
            CDSs (total)                      :: 3,805
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 87
            rRNAs                             :: 8, 1, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 55
            CDSs (without protein)            :: 55
            Pseudo Genes (ambiguous residues) :: 0 of 55
            Pseudo Genes (frameshifted)       :: 21 of 55
            Pseudo Genes (incomplete)         :: 28 of 55
            Pseudo Genes (internal stop)      :: 16 of 55
            Pseudo Genes (multiple problems)  :: 8 of 55
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6992
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941466-rid12468953.denovo.129"
                     /strain="01A10CD0081"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            97..1257
                     /locus_tag="KR231_003585"
     CDS             97..1257
                     /locus_tag="KR231_003585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF819 family protein"
                     /protein_id="HBH0005911.1"
                     /translation="MIETGFVYCSFLVVFVGVIFFMVDKLKWKVFDVINPMLLIYLGS
                     AILGSFGLFAQNEDVGTYQNIITVNFLPLMLVFLLIQCDLRKILKMGPKMLLSFFCAT
                     FTFMLGFVIAFIIFKNSMGADSWKILGAASGSWIGGSSNMIAAANALGVAEEGLSYAI
                     LMGSIGYTVWMSVCLMSVKFGPKFNKWTKCDTSFIDEVTSKLEKENKDNTAPTFVELM
                     ILLSVGFGVASFAQIVSKILPTSGILNETMWVVLVASTVSILLGMTKISKLKGSTLVG
                     NVFMYLLLAATGSKANFFGLSEAPVYIMFGLVVVLVHAISFIGLAKLFKLDLFTCEVG
                     SIANIGGVTTAPMIAGVHNPVLIPVGVLMGLLGNIIGTYCALMVTQILHMLA"
     gene            1600..1761
                     /locus_tag="KR231_003586"
     CDS             1600..1761
                     /locus_tag="KR231_003586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0005912.1"
                     /translation="MIIPSRRIQDITLTNLKNGEVTLIELDEIYKKMGFLFVVSEGKL
                     KKIKKENHH"
     gene            1954..2583
                     /locus_tag="KR231_003587"
     CDS             1954..2583
                     /locus_tag="KR231_003587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="HBH0005913.1"
                     /translation="MKIVTYNIHKGMDSNNRLTLTKMGLYLKQLDCDVICLQEVLYPQ
                     FLALKAVLNMGGVFATNVKKVNMIYGICTFTTSKMLNSNHFFLTSKKEQRGALCITID
                     AYGRIINVINTHLGLDRQERAKQLDEIIDYRNRLVGIVILCGDFNEKNVFLSMFNDMA
                     ISLNKSYLPTFEKSNSRIDYIFVNKNTELKGYTVEKIYLSDHYPVIGYI"
     gene            2823..4082
                     /locus_tag="KR231_003588"
     CDS             2823..4082
                     /locus_tag="KR231_003588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanW family protein"
                     /protein_id="HBH0005914.1"
                     /translation="MGRRTTRVSRLGKEKKRSVLIVLAALVLIMGGFTYFFNSKFLYN
                     GKIAKNVYIEGVNVSDMTKAEALKAITDKYTPEDLNLAYDGKKYTISPKDIDLKYDTE
                     DVVKDAYESTKKGSYFQNLKKYIDIRVNKANMKIKAEYDEAKLSSKVSSIADSINVKM
                     KNASISVGSGGLSYTDSVVGREFDLAANKESIYNMIKNKEHKTLELKVNLQKPDITTE
                     QVKTVNSVIGQYSTTYSQAVEGRSYNVGLSARKTSDVLLMPGEEFSYNKLTGPSNKAN
                     GYKDAPVIVYGKLEQSAGGGVCQTSSTVYNAALLSGMEITQVTNHSSASTYVPKGRDA
                     TVSDGGLNLKFKNPYKHPVYIKNYAGGGSVSSVIYGNSGDKPNISIEVKQTGQNKYST
                     YRIFKDSSGKVIKKEHISNSSYKELKK"
     gene            4341..5336
                     /locus_tag="KR231_003589"
     CDS             4341..5336
                     /locus_tag="KR231_003589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein kinase"
                     /protein_id="HBH0005915.1"
                     /translation="MYEEVTWLNFIGNRYEVVNSDDVLEINKIYKARDVFYRKNVLIK
                     VIKHNNYICEDFVSNLIDESTALDEINSPYILKIIDVGIHCTEETTLYYVVSEDFNGI
                     GLDELILGNYLHLEAIVNIMIQVLKALEMIHRNHSYHGSLKSSSIIVDTEYNIKICDF
                     GITKANNGVNTRSYGNRRYLCPHQLCINYTDKESDFFATGLILFESIFKKLPFGESNS
                     EEKMLQSIDKGLDWNSIKAINGNTELINVIKRLLGRNNKYTRANDIIIDLSKVMYEKA
                     YIEVEDEKEEEQKQDKVIQVKKEYKSKMRKKLHKKLVVAGLAIVMISMIIISSII"
     gene            5582..6649
                     /locus_tag="KR231_003590"
     CDS             5582..6649
                     /locus_tag="KR231_003590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA ligase RtcB family protein"
                     /protein_id="HBH0005916.1"
                     /translation="MSNIKIIASNKCWIEDIARKQLEDISKLNGILRVVGLPDLHAGK
                     IPVGLAVETKNIIYPHIIGNDIGCGMTLFKTGVLKKKFKKDKWIKSLSKIKDLSDIEI
                     KNTYKEECPILNLGTIGSGNHFVEIQCISEIYNKEQFEQLKFSSDDIMMLVHCGSRNY
                     GEDILKKFYDKDGLEVESEKAIDYIKKHDNALMWAERNREAISKKIMQSIGTSGDVET
                     IFSINHNFIEKREDKFIHRKGAVSSERGAVIIPGSRGSLSYIVMPTENTEISLYSLSH
                     GAGRKWSRSVCKSRLKSKYNKDTIKQTKFKSQIICNDVNLLFQEAPEAYKNIEQIIES
                     LIEYELIQVVATMKPLITYKG"
BASE COUNT         2773 a          686 c         1197 g         2336 t
ORIGIN      
        1 taaaagtatt tattttaatt gtctattatc tgaaaaagtc tttacttaga aatcataaaa
       61 atcaaattaa ttaggaaaag aaagggtgtg tataatgtga ttgagactgg atttgtatat
      121 tgtagtttct tggttgtatt cgtaggtgta atttttttta tggttgataa attgaaatgg
      181 aaggtatttg atgttattaa tccaatgctt ttaatatact taggttcagc tatacttgga
      241 tcatttggtt tatttgcaca gaatgaagat gttggaacgt atcaaaacat aataacagtg
      301 aacttccttc cattaatgtt agtgtttttg ttaattcaat gtgatttaag aaaaatatta
      361 aagatggggc ctaaaatgtt attatcattt ttctgtgcta catttacatt tatgcttgga
      421 tttgttatag cattcataat ttttaaaaat tcaatgggtg cagattcatg gaaaattctt
      481 ggggcagcat ctggttcatg gataggtggc tcatcaaata tgattgcagc agctaatgct
      541 ctaggagttg cagaagaagg acttagttat gcaatactta tgggttctat aggatataca
      601 gtatggatgt ctgtttgtct aatgtctgtg aaatttggac ctaaatttaa caaatggaca
      661 aagtgcgata caagttttat agatgaggtt acatcaaaac ttgaaaaaga aaataaagat
      721 aatacagcac ctacgtttgt agaacttatg attttacttt ctgttgggtt tggagttgcg
      781 tcttttgcac aaattgtatc caagatactt ccaacttcag gtatacttaa tgaaactatg
      841 tgggtagtac ttgttgcatc tacagtatca atattattgg gtatgacaaa aatatcaaag
      901 cttaaaggga gtacactggt aggaaatgtg tttatgtatt tactccttgc agctacaggt
      961 agtaaagcaa atttctttgg attgtcagaa gcacctgttt acataatgtt tggattggta
     1021 gtagtccttg tacatgctat ttcatttata gggcttgcta aactatttaa acttgattta
     1081 tttacttgtg aagtaggaag tatagctaat ataggaggag taactacagc tccaatgatt
     1141 gctggggttc acaatcctgt attaatacca gtaggtgtac ttatggggct tctaggaaat
     1201 attataggga cttattgtgc tcttatggta actcaaatat tacatatgtt agcttaatga
     1261 aaatatggta taaaattaat aatttaaata agaaaagtca tttcaattta agcagaagct
     1321 tttactgaaa tggctttttt tgtttgacaa gataatctat ttcaagaaga tgttttgaca
     1381 tatttagtgt ataatattgt aaaatttact aaaaacgaga tatatttaat ttttatattg
     1441 aatcgaacgt ctgtatgatg tataataaat atacagaacg aatgtttgcg gaacgggtgt
     1501 tttttgaatt tattttaata atttatgaat atatatcaga atgcataaat atatttaaat
     1561 ataaagatta aaaagaattt aaaggagtgt tgataactta tgataattcc atcaagaaga
     1621 atacaagata taacattaac aaatttaaaa aatggtgaag taactttaat tgaattggat
     1681 gaaatataca agaagatggg atttttattt gttgttagtg aaggcaaatt gaaaaagata
     1741 aaaaaggaga atcatcatta gaaatgaatg aaataataaa tattataata gtttataaaa
     1801 cctaacttat gtagaatata aatacttaag ttaggttttt ttgtgataaa gtttataagt
     1861 actcaatttt ataagataaa taatggtttt aagtgaaaag taaataagtt taaattttag
     1921 taagtattat attgcataag aggtgatatt attatgaaaa tagtaaccta caatattcat
     1981 aaaggtatgg attcaaataa tagattaact ctaactaaaa tggggttata tttaaaacaa
     2041 ttggattgtg atgtaatttg tttgcaagaa gtattatatc ctcaattttt agctttaaaa
     2101 gctgttttaa atatgggtgg tgtctttgct acaaatgtaa aaaaagtaaa tatgatatat
     2161 ggtatttgta catttacaac atctaaaatg ttaaacagta atcatttttt cttaactagc
     2221 aaaaaagaac aacggggagc tctttgtata actatagatg catatggaag aattataaat
     2281 gtaataaata ctcacttggg acttgatagg caggagagag caaaacaatt agacgaaata
     2341 atagactata ggaacagatt agtggggata gttattttat gtggtgattt taatgagaaa
     2401 aatgtctttt taagtatgtt taatgatatg gctatttcac taaacaagtc ttacttacca
     2461 acatttgaaa aatcaaactc tagaatagat tacatttttg ttaataaaaa tactgaacta
     2521 aaaggataca cagtagaaaa aatttacctg tcagaccatt atcctgtaat aggttacatt
     2581 taaatttcaa tataaatgaa attagttgtt ataaaataaa caattttttt gttaagaaat
     2641 agtaaaagaa atataataaa aaatatcaaa aataaaacta attataagac ataaatttac
     2701 aataaagtta catttgatta aattccttgt ttaacaaaag ctattcaaat ataatctaag
     2761 gtagttttga aatgggaact ctattatgca aatttaagct agtgttaaaa tgaggtgaag
     2821 ttatgggcag aagaacaaca agagtttcaa gattaggtaa agaaaaaaaa cgaagtgttt
     2881 taattgtatt ggcagcttta gttctaataa tgggtggatt tacttatttt tttaacagta
     2941 aatttctgta caatgggaaa atcgctaaaa atgtatatat agaaggagta aatgtatctg
     3001 atatgactaa agcagaggca ttaaaagcta taacagataa gtatactcca gaagacttaa
     3061 atcttgctta tgatgggaaa aaatatacaa tatcaccaaa agatattgat ttaaaatatg
     3121 atacagaaga tgttgtaaaa gatgcttatg aaagtacaaa aaaagggtcc tattttcaaa
     3181 acttaaaaaa atatattgat ataagagtga ataaggcaaa tatgaagata aaagctgaat
     3241 atgatgaggc aaaacttagt tccaaagtgt cttctatagc agatagtata aatgttaaga
     3301 tgaaaaatgc ttctattagt gttggaagtg gtggactaag ttatacagac tctgttgtag
     3361 gtagagaatt tgatttggca gcaaataaag agtctatata taatatgata aaaaataaag
     3421 agcataaaac tttagaactt aaagtaaatc ttcaaaaacc agatataaca actgaacaag
     3481 taaaaactgt aaattctgtt ataggtcaat attcaactac ttattcacaa gctgtagagg
     3541 gtaggtcata taatgtagga ttatcagcaa gaaaaactag tgatgtatta ttaatgccag
     3601 gtgaagaatt ttcatacaat aaacttacag gacctagtaa taaagcaaat ggttacaaag
     3661 atgcacctgt tatagtttat ggtaagctag aacaatcagc aggaggaggt gtttgtcaaa
     3721 catcttcaac agtttataat gctgctcttc tttcgggtat ggagataact caagttacaa
     3781 atcattcatc tgcatctact tatgtgccta aagggagaga tgctactgtg agcgatggag
     3841 gattaaactt aaagtttaaa aatccatata agcatcctgt atatattaaa aattatgcag
     3901 gtggaggaag tgtatcatca gtaatctatg gtaattctgg tgacaaacca aatatatcta
     3961 tagaggtaaa acaaactggt cagaataaat attctacata tcgaatattt aaagattcaa
     4021 gtggaaaggt cataaaaaaa gaacatatat caaatagttc ttataaagaa ttaaaaaaat
     4081 agataatttt ttagagaaat atttgtaata taaaagggag tgtctcaaaa tgaacttttt
     4141 agtttatgag gcactctttt tctgtgaaat caaatatatt ttcatcattt caacaataca
     4201 aaagaagcgt atctctattt tgagacagcc ttttttgtaa aaattaacac tattagttct
     4261 tgttttaata ttacaatcat taatatatag aaaatattcc tatatattgg tataattgta
     4321 aatagattta gttatataaa atgtatgagg aggtgacatg gttgaatttt ataggcaata
     4381 gatatgaggt agtaaattct gatgacgttt tagaaattaa caaaatctat aaagctagag
     4441 atgtttttta caggaaaaat gtgttaataa aagttataaa gcacaataat tatatctgtg
     4501 aagattttgt ttcaaattta attgatgaaa gtactgcttt agatgagata aactctcctt
     4561 atatactaaa aataatagat gttgggattc actgtacaga agaaacaaca ttatattatg
     4621 ttgtaagtga agactttaat ggtatcggac tagatgaatt aattctaggt aattatcttc
     4681 atttagaagc aattgtaaac ataatgatac aagttttaaa agctttagaa atgatacata
     4741 ggaatcattc atatcatggt agtttaaaat cgagtagtat aatagtagat acagaataca
     4801 atataaaaat ttgtgatttt ggaattacaa aagcaaataa tggggttaat acaagaagct
     4861 atggaaacag gagatattta tgcccacatc aactatgtat aaattatact gataaagaaa
     4921 gtgatttttt tgcaacaggt cttattctat ttgaatctat atttaaaaaa ttgccttttg
     4981 gagaatcaaa ttcagaagaa aaaatgctac aatctattga taagggatta gattggaata
     5041 gtataaaagc aattaatgga aatactgaac ttataaatgt tataaaaagg cttcttggaa
     5101 gaaataataa gtatactaga gccaatgata ttattattga tttaagtaaa gtaatgtatg
     5161 aaaaagcata tatagaagtt gaagatgaga aagaagaaga gcagaaacaa gacaaagtta
     5221 tacaagttaa aaaagaatat aaaagtaaaa tgagaaaaaa attacataaa aaacttgttg
     5281 ttgccggtct agctatagtc atgatttcaa tgattattat tagttccata atataaaaat
     5341 tgtatattaa gtattttaaa atcaatgtct ataaaggata tacatagaaa ttttagtgta
     5401 gtcttaaatt atgaaaggaa gtggttatta tgttaacaaa aaataatgag gtattaaacg
     5461 tctaggagta ttttaacaaa tagccacctg cttttacagt ttagaataaa aaagctgtgg
     5521 ctaaaggtca cagctttttg ctacttttta aaggcaggag aatattaaaa aggagcaaat
     5581 tatgagcaat ataaaaataa tagcaagtaa taaatgttgg attgaagata tagcaaggaa
     5641 acaacttgaa gatatttcaa agttaaatgg aattttaaga gtagtaggat tacctgactt
     5701 acatgcaggt aaaatacctg taggtttagc agttgagact aaaaatatta tttatccaca
     5761 tataattgga aatgatatag gatgcggaat gactttattt aaaactgggg ttctaaaaaa
     5821 gaaatttaaa aaagacaaat ggattaagtc acttagtaag attaaagatt tgtccgatat
     5881 agaaataaaa aacacatata aagaagaatg tccaatttta aatttaggaa ctatagggag
     5941 tggaaatcat tttgtagaaa ttcaatgtat aagtgaaatt tataataaag aacaatttga
     6001 acaattaaaa ttttcatctg atgatattat gatgttagtt cactgtgggt caagaaatta
     6061 tggagaagat attttaaaaa aattttatga taaagatgga cttgaagttg aaagtgagaa
     6121 agctatagat tatattaaaa aacatgataa tgctttaatg tgggcagagc gtaatcgtga
     6181 agctatcagt aaaaaaatta tgcagtcaat aggtacatct ggagatgttg aaacaatatt
     6241 ctctataaat cataatttta tagagaaaag ggaagataaa tttatacata gaaaaggtgc
     6301 tgtttcaagt gaaagaggag ctgtgattat accaggttca agaggcagtc tatcatatat
     6361 agttatgcct actgaaaata cagagatatc tttatattct ctatcacatg gagcaggtag
     6421 aaaatggtct cgttcagttt gtaaatctcg ccttaaaagt aagtataata aagatactat
     6481 aaaacaaact aaatttaaaa gtcagattat atgtaatgat gtaaatttat tatttcaaga
     6541 agctccagag gcatataaga atatagagca gattattgaa agtttgatag aatatgaact
     6601 tattcaagta gtggcaacta tgaagccatt gattacttat aaaggataat ttttaaagtt
     6661 aaaaaagatt aaaattatat tataaatagc taattttatg gaacatttaa aagtgtttta
     6721 ttattagcta tttttttatt ttgtagagac gataatttat agagctaaat tctttgatat
     6781 ataatgatta caaagttaga ctgtattgga aaatgcacat acatgaattg atgacaatat
     6841 aagtgattcc caaatataaa tgaaagtata agcttatttt cactataaaa attttcactg
     6901 tacaaaaaca ttaatgacat tatttttatt gacataaata tataatttat ggaataatat
     6961 tagaagcact gatataagtg tttaaataag aa
//
LOCUS       DAEPHU010000129         6901 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 01A10CD0081
            SAMN05941466-rid12468953.denovo.130, whole genome shotgun sequence.
ACCESSION   DAEPHU010000129 DAEPHU010000000
VERSION     DAEPHU010000129.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941466
            Sequence Read Archive: SRR6291087
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 6901)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6901)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068158.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 22:43:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,892
            CDSs (total)                      :: 3,805
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 87
            rRNAs                             :: 8, 1, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 55
            CDSs (without protein)            :: 55
            Pseudo Genes (ambiguous residues) :: 0 of 55
            Pseudo Genes (frameshifted)       :: 21 of 55
            Pseudo Genes (incomplete)         :: 28 of 55
            Pseudo Genes (internal stop)      :: 16 of 55
            Pseudo Genes (multiple problems)  :: 8 of 55
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6901
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941466-rid12468953.denovo.130"
                     /strain="01A10CD0081"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            492..1766
                     /locus_tag="KR231_003591"
     CDS             492..1766
                     /locus_tag="KR231_003591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class V-fold PLP-dependent
                     enzyme"
                     /protein_id="HBH0005917.1"
                     /translation="MQFMDVSKYIEGANLKVKTKNGETVKRIYFNNSATPLVLKNVVD
                     NLNCEIPWLTYINAPGIISEKNTLKYENVRSTILKLIDGDEEKDSVIYVKNATEGINF
                     LAKFFKDENPDKFVITTAMEHMANYLPFKVNFPTKVVGITEKGELDLCQLENILKNYA
                     GNVSLVTVTGASNVTGITTPIYEIARIAHKYGAKILVDIVQVIQHKPFSMMPHECDEH
                     IDFVVFSAHKCYSPLNGGALVGPKKFFEKFNPVLYGSGSTKFVNDNKILYANVPQRFE
                     AGYPEYFGTLAMGKALNTLNKIGLNRISKYERELFLYAKEEMSKIPNIIIYGDKSNNV
                     IIPNISFNISNMYYKDVAKYLVDNFGIETGAGVVGADIYVQKLLGINPKEAYVRFMRE
                     NPVGLVRISLGMYNTFDEVDSFIHAIKTLAFK"
     gene            complement(1973..2290)
                     /gene="trxA"
                     /locus_tag="KR231_003592"
     CDS             complement(1973..2290)
                     /gene="trxA"
                     /locus_tag="KR231_003592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin"
                     /protein_id="HBH0005918.1"
                     /translation="MVKIINNNEFINEVENKDGLVVVDFFATWCGPCKMLSPIYEALG
                     NEMVEKANFLKVDIDQSIELAQKFEVSTVPTMLIFKDGKPVDRLIGFMPKENLKNKIE
                     SYM"
     gene            2557..3309
                     /locus_tag="KR231_003593"
     CDS             2557..3309
                     /locus_tag="KR231_003593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrmB family transcriptional regulator"
                     /protein_id="HBH0005919.1"
                     /translation="MDNIINELQNIGFTKYESQIYISLLKESPLTGYEISKLSGVPQS
                     KVYENITKLLNNNIIINVGTDPIKYIPINPNELLKNKKKEFDNSMDNLKNSLQILNKS
                     KSVEYVLNIKGDKNILKKAIEMIKNAKQEIIISCPYEEILELKKELLIAYKKNINIEI
                     LLLENKSLKGLDNIHIHGGNKTTLENKMLYKGIILIVDNDEILTGNLSEGSEAISIWT
                     KNSNILYIGVQYIKHEIYISEQIKGGYKNEQN"
     gene            3296..4177
                     /locus_tag="KR231_003594"
     CDS             3296..4177
                     /locus_tag="KR231_003594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PhzF family phenazine biosynthesis protein"
                     /protein_id="HBH0005920.1"
                     /translation="MNKIKIKQVDAFTTIPFGGNPAGVVTDASNISDEIKQNVAKEMN
                     LSETAFVSESNIADFKVQFFTPGLEVDLCGHATIGTFHALLEEGKLNTNKSIFYQETK
                     AGVLSVELKKINNENIFMMEQNTPEFENLDNCRKELAQMIGVHEDRLLEYPIIKVNTG
                     LWWLVFGLKSLDDLKNISPDLNKIKKFSGDNNIIGITPFCIETIDKKCDYHLRSIAPY
                     VGVTEDPVCGTGNACVSSYIVHHNILDKTSFIGEQGNFINRPGKVYVNITRENNDITS
                     VKIGGSAYTILSGEIMY"
     gene            complement(4403..5758)
                     /locus_tag="KR231_003595"
     CDS             complement(4403..5758)
                     /locus_tag="KR231_003595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide MFS transporter"
                     /protein_id="HBH0005921.1"
                     /translation="MSSTVKKKGKFPMGFYICSTTFSFERAAYYASKYLIYIFLTTAI
                     VHGGLGIDKGQAAIMQANLVAFTYLAPIIGGYISDRWIGARYTIPIGMLIMGVGYYLG
                     SIATTVSMVNAMIILVSIGTAFFKGNVSAVNGQLFDSQEELDTAFSVQYSFVNIGSFI
                     GTIAVGILYLKTFAKNGVLGFSQCFFIAAVLCVIGAIWFIYGWRFLGNAGKRPFKEGV
                     VAEKIEEKDKSPLTSMDKKRIWAIILISFFSVIFWVFWYLTYLAVYDYGAAFVNMNVG
                     GFDVPLAWFDSLNSLVCIVLGPVLGALWFKLASRPQGDMSLFKKTGLGLIFLGLAFLM
                     LVGAEFSRGVGAPETAKASILWIIMFGILLSLGEMLFSPLGNSFVSKYAPKKLLGVLM
                     GVWTFATFIAGKGYGYIYAFTLKFDMIKVYTIIPVILFVAAILLFLSDKTLSRLVEDD
                     K"
BASE COUNT         2654 a          963 c          848 g         2436 t
ORIGIN      
        1 attggtaata taattttttt tataaaatta tttgtattat attttgtatt ttttataaaa
       61 ttattatact tgtacatctt ttataacata taaaatcttt ttttctaatt atatacaata
      121 tattttccat tatgttctaa tcaatttctt tactattttt acaactttat tagtcatatt
      181 cataattatt tctaattagt gtttaacatt ttatgtaaaa tttataaaaa aatgtatata
      241 aattaaaata agtgactata ctaaaaatat gatacggata aacaataagt tcaacctatc
      301 tcccccaaaa tcaagtgagc tacagtttcc cccaactgta gctcattttc gtgtaattta
      361 ataaacatct caacaagaat taattaacaa aaccccttat aaaaacataa catatattaa
      421 acaagctctt gattaaaact tgagcttttt taataaaaaa cagaatagtt tattagataa
      481 ggggtttttt tatgcaattc atggatgtat ctaaatacat tgaaggtgca aaccttaaag
      541 ttaaaactaa aaatggtgaa actgttaaaa gaatatattt taacaactct gccactccat
      601 tagttttaaa aaacgtagtg gataacttaa actgtgagat tccttggctt acttatatta
      661 atgctccagg aataatctca gaaaaaaata ctttaaaata tgaaaatgta cgctctacta
      721 tcctcaaact tattgatgga gacgaagaaa aggattctgt tatttatgtc aaaaatgcta
      781 cagaaggaat aaacttctta gcaaaatttt ttaaagatga aaatccagat aaatttgtta
      841 ttaccacagc aatggagcat atggctaatt acctgccttt taaagttaat tttcctacaa
      901 aagttgttgg aattacagaa aaaggagaac ttgatttatg tcaattagag aatatactta
      961 aaaattatgc tggtaatgta tctctcgtta cagttacagg agctagtaat gtcacaggta
     1021 taaccactcc tatatatgaa atagcaagaa tagctcataa gtatggtgca aagatattgg
     1081 tggatattgt gcaagtaatt cagcataaac ctttttcaat gatgccacat gaatgtgatg
     1141 agcatataga ttttgttgtt tttagtgctc ataaatgtta ttctccacta aatggaggag
     1201 ctctggtagg acctaaaaaa ttctttgaaa aatttaatcc tgtactatat ggctcaggtt
     1261 ctaccaaatt tgtaaatgat aacaaaatac tatatgcaaa cgtaccccaa cgttttgaag
     1321 caggataccc agagtatttt ggaactcttg caatgggaaa agcactgaac actttaaata
     1381 aaattggtct aaacagaatt tcaaaatacg aaagagaatt atttttatat gctaaagaag
     1441 aaatgagtaa aatacctaat ataataatat atggagataa atcaaataat gtaattatcc
     1501 caaatatatc ttttaatata agtaatatgt attacaaaga tgtagcaaaa tatttagttg
     1561 ataactttgg aatagaaact ggagctggag tagtaggtgc agatatttat gtacaaaaat
     1621 tattaggtat aaatccaaaa gaggcatacg tcagatttat gagggaaaat cctgtaggtc
     1681 ttgttaggat aagcttagga atgtacaata cttttgatga ggtggatagc tttatacatg
     1741 ctattaaaac tttggctttt aaataagatt tttctattct tttttatcaa taaatagaga
     1801 gtagttttgt tttcacaaaa aaacaaatta tatcaacagt caatttcatt agcaattaga
     1861 cactcatttg taactataca aactatttta cactatacaa acaaaaaact cattacaatg
     1921 agtttttttg tttatatatg agatttattt taattacttc aatttacttt aattacatat
     1981 atgattcaat tttgtttttt aaattctcct taggcataaa acctattaat ctatctacag
     2041 gttttccatc cttaaatatt agcatagttg gtactgtaga tacttcaaat ttctgagcta
     2101 attctatact ttggtctatg tccaccttca agaagtttgc tttttcaacc atctcatttc
     2161 ctaaagcttc atatattggt gatagcatct tacaaggtcc acaccaagtc gcaaagaaat
     2221 ctacaactac taaaccatct ttattttcta cttcatttat aaattcatta ttatttatta
     2281 tttttaccat aatatacatc tcctttatta tcttcttgat attaatatac tacgccctat
     2341 ataacagttc aattaggcac ttttttgtaa ccgcctattt ttaatagatt taatattatg
     2401 ataaatagat ttataagatt aaatatttat gagactaaat atttctaata tattttattt
     2461 ttttcttaat atagttgaca ttttttccct taaattataa aatcaaatta ataactacat
     2521 aggtagttac taatctttta tcaaaggagt ttctatatgg ataatataat taatgaatta
     2581 caaaatatag gatttactaa atacgaatct caaatataca tatcattatt aaaggaaagc
     2641 cctttaacag gatatgaaat aagtaaatta tcaggtgtac cacaatcaaa agtctatgaa
     2701 aatataacaa agctattaaa caataatata attatcaatg ttggaactga ccctattaag
     2761 tacataccaa taaaccctaa tgaattatta aaaaataaga aaaaagaatt tgacaattct
     2821 atggataatc taaagaatag cttacagata ttaaataaaa gtaaaagtgt agaatacgta
     2881 ttaaacataa aaggagataa aaatatatta aaaaaagcaa tagaaatgat aaaaaatgca
     2941 aaacaagaaa ttataatttc ttgcccttat gaagaaattc ttgaattaaa aaaagaactc
     3001 ctaattgctt acaaaaaaaa tattaatatt gaaatactac ttttagaaaa caaaagtctg
     3061 aaaggtcttg ataatattca tattcatgga ggtaataaaa ctacacttga aaataaaatg
     3121 ctttacaaag gaattatttt gattgtagat aatgatgaaa tattgacagg aaacttatca
     3181 gaaggcagtg aggccatttc aatttggaca aaaaactcta acattttata tattggagtt
     3241 caatacataa aacatgaaat ttatatttca gaacaaataa aaggaggtta taaaaatgaa
     3301 caaaattaag attaaacaag ttgatgcttt tacaactata ccttttggtg gaaatcctgc
     3361 tggtgtcgtt actgatgcct ctaacatttc tgatgaaatt aagcagaatg tggctaaaga
     3421 aatgaattta tcagaaactg catttgtttc agagtcaaat attgcagatt ttaaagtaca
     3481 atttttcaca ccaggtttag aagttgattt atgtggtcat gcaacaatag gtactttcca
     3541 tgcacttttg gaagaaggga agcttaatac taataagagt atattttatc aagaaacaaa
     3601 agctggtgta ttatctgtag agcttaagaa aataaataat gaaaatatat ttatgatgga
     3661 acagaataca cctgaatttg aaaatttaga taattgcaga aaagaacttg cacaaatgat
     3721 aggtgtgcat gaagatagac ttcttgaata tcctattata aaggtaaata ctggactttg
     3781 gtggcttgta tttggtctaa aatctttaga tgatttaaaa aatatctctc cagatttaaa
     3841 taaaatcaaa aaatttagtg gtgataataa tataattggt ataactccat tttgtataga
     3901 aactatagat aaaaagtgtg actaccattt aagatctata gcaccatatg ttggagttac
     3961 agaagaccct gtatgtggaa ctgggaacgc ttgcgtatca tcttatatag tacatcacaa
     4021 tattttagat aaaactagtt ttattggtga gcaaggtaac tttataaaca gacctggaaa
     4081 ggtatatgta aatataacta gagaaaacaa tgacataact tctgtaaaaa ttggaggaag
     4141 tgcttatact attttaagtg gtgaaattat gtattaatcc catacctaat aaaaacaaat
     4201 aaaaatacta gctaactaaa gctagtattt ttatttgtta tttttattta ataatcatac
     4261 tctaacaaat attataatta tatatatcat aatattgtat ttagaagtaa aattttattt
     4321 ttattattaa ttagttataa atcaatctaa tacaacataa ttacagtaga ttaacctata
     4381 aaacataata attgcttact aattatttat catcctcaac aagtctactt aatgtcttat
     4441 cagataagaa taataatatc gctgcaacaa atagtattac tggaattata gtatatactt
     4501 taatcatatc aaatttaaga gtaaatgcat atatatatcc gtatccttta ccagctataa
     4561 aagtagcaaa tgtccatact cccataagaa cacctagaag cttcttaggt gcatacttac
     4621 ttacaaaaga gttaccaagt ggtgagaata acatttcacc aagacttaaa agaataccaa
     4681 acatgattat ccatagtata ctagctttag cagtttcagg agctccaacc cctcttgaaa
     4741 attctgcacc aacaagcatt aagaatgcaa gacctaagaa tattaatcca agacctgtct
     4801 ttttaaataa actcatatct ccttgtggtc tactagcaag tttaaaccat aatgctccaa
     4861 gaactggtcc taatactata catacaagtg aatttaatga gtcaaaccaa gcaagaggaa
     4921 catcaaatcc tccaacattc atgtttacaa atgctgcacc ataatcataa actgcaagat
     4981 aagttagata ccagaatacc cagaaaatta cagagaagaa tgatataagt ataatagccc
     5041 aaattctctt cttatccatg cttgtaagag gagacttatc tttttcttca attttttcag
     5101 caactacacc ttctttaaaa ggtctctttc ctgcattccc aaggaatctc catccatata
     5161 tgaaccatat tgcacctatt acacaaagta cagctgctat aaagaaacat tgagaaaatc
     5221 caagtacacc attttttgca aatgttttaa ggtaaagaat accaactgct atagtaccaa
     5281 taaaagaacc tatattaaca aaagaatact gtactgaaaa tgctgtatca agttcttctt
     5341 gactatcaaa aagctgtcca tttaccgcag atacgttacc tttaaagaat gcagtaccaa
     5401 ttgaaactaa gattatcatt gcatttacca tagaaactgt agttgcaata gaaccaagat
     5461 agtatcctac tcccatgata agcataccta taggtatagt atatctagct cctatccatc
     5521 tatctgatat atatccccca attataggtg caaggtatgt gaatgcaaca aggttggctt
     5581 gcattatagc agcttgtcct ttatctattc caagaccacc atgaactata gctgttgtaa
     5641 ggaatatata tattaagtac tttgaagcat aatatgctgc tctttcaaat gagaaagttg
     5701 ttgagcagat ataaaatccc ataggaaatt tacccttctt ttttactgtt gagctcataa
     5761 ttttaaatcc tttcttaatt gtatttttat tttttacgtt ttgtccaaat tctttctttt
     5821 atgaaagata taatattatt attttgtaaa acaatttgta attattatta agataattgc
     5881 gcatttattt gtagagtaca tattctcatg gaataaaatt aatacacttc ttaatcataa
     5941 atttaaatta tataaattca ctattttcag atatagttat aaattaatat attctcatct
     6001 aataccatga aaaaaccttc gccatatgca attcttattt tttacgtgat agtattttac
     6061 aaactaaaat cccccttttg tagcaactta tgtaattaca ttttagtgct tttttaaagg
     6121 agtctcgaat aaagcaacat atattttgtt caaataatgt ttttatttat tttttaaatt
     6181 tatatattac ttcactcaac caattctcaa cttaaataac taaactacta tctattcaca
     6241 gattaggctt atttcttaca cattagttta taataaacac tgtgaatcta aacataaaaa
     6301 ctgttatttt aaagtaatta cccatatatt cgctttgata ctatttattg aggttatact
     6361 ctttatgtat aatatattat ttataaaata cctcaaaata tattattcat aaaatacctc
     6421 aaactgaaaa ctttttcacg aatatttatt tttcacctcc ccttttttat ttcaccatgt
     6481 aaatcgtacc ataaatatgc acttatatgc aagaaaaaaa tctattaatc gacagtaaat
     6541 aattagaaaa attcaaatta tatttatcaa gtatattata taaaatattt cctatgaaaa
     6601 tataaattaa attaatgttc agaattgttt ttagatatga aatcttgatt tttttattac
     6661 tttacttatt tgctcaaata tatttttgta tgcagtatat aataatcaaa ttatacactt
     6721 cttataactg cattgatttg aaaataatat taataattaa tagaataaaa aatttaaatt
     6781 aaatttaaaa aaatttgtta agttgattga atactttttt atgtatttaa ttaattttat
     6841 aaattcaatt attttctaaa tttaggtatg ctttactata taaaaatgat tttttatctt
     6901 a
//
LOCUS       DAEPHU010000130         6884 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 01A10CD0081
            SAMN05941466-rid12468953.denovo.131, whole genome shotgun sequence.
ACCESSION   DAEPHU010000130 DAEPHU010000000
VERSION     DAEPHU010000130.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941466
            Sequence Read Archive: SRR6291087
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 6884)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6884)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068158.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 22:43:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,892
            CDSs (total)                      :: 3,805
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 87
            rRNAs                             :: 8, 1, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 55
            CDSs (without protein)            :: 55
            Pseudo Genes (ambiguous residues) :: 0 of 55
            Pseudo Genes (frameshifted)       :: 21 of 55
            Pseudo Genes (incomplete)         :: 28 of 55
            Pseudo Genes (internal stop)      :: 16 of 55
            Pseudo Genes (multiple problems)  :: 8 of 55
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6884
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941466-rid12468953.denovo.131"
                     /strain="01A10CD0081"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            complement(441..2828)
                     /gene="cadA"
                     /locus_tag="KR231_003596"
     CDS             complement(441..2828)
                     /gene="cadA"
                     /locus_tag="KR231_003596"
                     /EC_number="7.2.2.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cadmium-translocating P-type ATPase"
                     /protein_id="HBH0005922.1"
                     /translation="MEANNSIKKEFILGGLNCAHCAEEINNKVSKLQEVKSSNLNFIN
                     KKLTVNIKESFNEDTTIEKIIDIIDSTDPGLDIQISSKENAASKTSIKKELILGGLNC
                     AHCAEEINNKVSKLKEVESSNLNFVNKKLTVNISNNFEEDDVINKIKEIINSTEPGLD
                     IQVGSTDKVKGRTTEKSGAVNDTNKKELIPLIIGALVYIFGIYQTATGYESQFSNIVF
                     IVAYVIVGGDVLLRAIRNISKGRVFDENFLMALATVGALTIGELSEAVGVMLFYKVGE
                     YLQGVAVGKSRKSITSLMQIRPDYANLKVNSEVKVVSPEEVNVGDIIVVKPGEKVPLD
                     GVVVDGVSMLDTSALTGESVLREVEKGDEILSGVINKNALLSIEVTKSFGESTVSKIL
                     DLVENSSIKKSKTENFISKFSRYYTPIVVIAALLIAFVPPLVISGEVFSDWLYRGLIF
                     LVVSCPCALVLSIPLSFFSGIGFASKNGILIKGSNYLEALRSVDTVVFDKTGTLTKGV
                     FNVTKLNPEGISEEELLEYAAIAEVNSNHPIAKSILSYYNKKIDLDTIDSYEEIAAYG
                     IRVKHNGNFILAGNEKLMKKENISYSSAKEVGTVVYIAVDKVYRGYIVISDEVKEDSK
                     NAIRSLKEIGVKEVVMLTGDNEKVAKNIAQELELDTVYSNLLPNEKVDRLEDLYEGRT
                     EKEKIAFVGDGINDAPVLARADVGIAMGGLGSDAAIEAADVVLMTDEPSKISKAIEIA
                     NKTNKIVWQNIIFALGVKIIVMILGAGGVATMWEAIFADVGVALIAVVNAMRAMR"
     gene            complement(2851..3216)
                     /locus_tag="KR231_003597"
     CDS             complement(2851..3216)
                     /locus_tag="KR231_003597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBH0005923.1"
                     /translation="MREEINDCNCNIVHEEIVTEAKSTMPDEEMLYDLAELFKVFGDT
                     TRVKILYALFANEMCVCDIASLLNMTHSAISHQLRVLKQARLVKFRREGKTVYYSLDD
                     SHISQIFDCGLNHIRETYK"
     gene            3415..4263
                     /locus_tag="KR231_003598"
     CDS             3415..4263
                     /locus_tag="KR231_003598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0005924.1"
                     /translation="MSNKKKKDLDTSYMPYLDPANYADYITNEEIPQDELRNDPQISN
                     GYTKIPNNQNINNLYPNNVNHYPKSSNSPNNLPNTNNTSGNMNYNTSATNNMPNNMNN
                     NTGMPNNMSNNMNSNMGMPNNMPNNMNSNMGMPNNMPNNMNSNMGMPNNVPNNMNSNM
                     GMPNNMSNNMNSNMGMPNNMSGNMNNNMYGNTGMPNNMNSNMGYNMNNTMGIPNFSCN
                     QNMPPNVLMMIPGVICHNTMQGMPVVMPSTMPPNIYPTPYGSSNMSVQGIPQATNIEE
                     FDEEEM"
     gene            complement(4700..5788)
                     /locus_tag="KR231_003599"
     CDS             complement(4700..5788)
                     /locus_tag="KR231_003599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0005925.1"
                     /translation="MNFNFAKATNSRLMGSLGLIINWIDDENNHFCQYFLLDAEGLGL
                     ADYVSLNNPTQEEAYMEEERLMGGFGSDRVELTKDESLFLVSYFGNKNLYYDKLLPGD
                     KCEYIDIIKNYKTDLTIEKLYNKICKRVDEEVEFINYMTMRFIAWDRESLKYFSGSDE
                     IANMHITNINGTLLKNVVSDKGQGRYISEALYEDNDGYYICKIAFCISKCYETGFRIN
                     SLLVTDKEPMYDFEVFDEISKSEFVSVYSVNSPEEFAGVFYRENPFLLKSNMNEGIFF
                     TRFNFNNDHVKENVYIINNDMKAIYYLMGNKFFIGTYNENDCNYINEISQSNYSDYIK
                     FEEKFFFEQNALYDFAESGSLDFDDFLE"
     gene            5913..6641
                     /locus_tag="KR231_003600"
     CDS             5913..6641
                     /locus_tag="KR231_003600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IB family hydrolase"
                     /protein_id="HBH0005926.1"
                     /translation="MKNIAAFFDIDGTLYRDSLMVEHFKKLIKYDIIDQKNWYKHARD
                     TFMDWDKRQGNYDDYLLEICDLYVDSLKGLDKTCINFTSDQVIKLKADRVYKYTRSRI
                     EWHLNQGHIVIFISGSPGFLVEKMAKKYNVTDFLGSDYVFENNIFTGTVIPMWDSISK
                     NNAINDFVVKYDLDLSNSYAYGDTNGDINMLKRVGNPIAINPTKELLSQISLDEEISK
                     NVEIIVERKDIIYSLSTDVNIVDI"
BASE COUNT         2428 a         1133 c          734 g         2589 t
ORIGIN      
        1 cttaaaaata attcgtcaat actttttaaa attatttttt aaaaatattt actttcttat
       61 attacataat ttattgaatg gcagtcatac tgttggttta gagtatttta acacacacat
      121 tttgttgtaa aaattacaac tattaatata atatatatac aatcataagt attataattt
      181 ttatgaatct aatttaaact taatataaac ttattaataa accttctatg tctaaatttt
      241 aaaattacaa tataaaagct ctacactaaa taaatacatt aaataaacat aatggataat
      301 gaatataaat ttatatatgc aaagcgctcc aataaaaagg taccaataaa gttaaaagaa
      361 acttattgat acctttcatt attacatact tcaatatata attataagtt ttttaaatag
      421 tatggattta catttatccc ttatctcata gctctcatag catttactac tgctataagt
      481 gccacaccta catcagcaaa tatagcttcc cacatagtag ctactcctcc agcacctagt
      541 atcataacta taatttttac tcctagagca aatattatgt tttgccacac tatcttatta
      601 gtcttgtttg ctatttcaat tgctttagat atcttgctag gctcatctgt cataagcact
      661 acatctgcag cttcaatagc agcatctgaa cctaagcctc ccatagctat accaacatca
      721 gcacgagcta atactggagc atcatttatt ccatcaccta caaacgctat tttctctttt
      781 tcagttcttc cttcatataa atcttctaat ctatctacct tttcattagg aagtaaattt
      841 gagtaaactg tatccaattc taattcttga gcaatatttt ttgctacttt ctcattatct
      901 ccagttaaca ttacaacttc ttttacccct atttctttta agcttcttat ggcattttta
      961 ctatcttctt ttacttcatc agagataact atataacctc tatatacttt atcaacagca
     1021 atatagacta ctgtgcctac ttctttagct gatgaataag atatattttc ttttttcata
     1081 agtttctcat tacctgctaa tataaaattg ccattatgct ttactctaat tccataagct
     1141 gctatttcct cataactgtc tattgtatct aaatcaattt ttttattata gtaacttaat
     1201 atggactttg ctattggatg atttgaattt acctccgcaa tagctgcata ttctaataat
     1261 tcttcttctg atataccttc aggatttaac ttagttacat tgaacacacc tttagtaagt
     1321 gttcctgttt tatcaaatac tactgtatct acacttctta aagcttctaa atagttactt
     1381 cctttaataa ggataccatt tttagatgca aacccaattc cactaaaaaa actaagtggt
     1441 attgataaaa ctaatgcaca agggcaagaa acgactaaga atatcaatcc tctatataac
     1501 caatcactaa atacctcacc tgagattaca agtggtggca caaatgctat taataaagca
     1561 gctattacta ctattggagt atagtatctt gaaaacttag atataaagtt ttctgtcttt
     1621 gattttttaa tgctagaatt ttcaacaagg tcaagaatct tagaaactgt tgattctcca
     1681 aaactctttg taacttcaat actcaataaa gcatttttat ttataacacc tgataagatt
     1741 tcatctcctt tttcaacttc tctcagcact gactctcctg tgagtgcaga agtatctaac
     1801 atagaaactc catctactac tacaccatct aatggtactt tttcaccagg ttttactact
     1861 attatatcac ctacatttac ctcttctggt gacaccacct taacttcaga attaactttt
     1921 agatttgcat agtctggtct tatttgcata agtgaagtta tagactttct ggatttacca
     1981 actgcaacac cttgtaaata ctctcctact ttatagaaaa gcataacccc tactgcttct
     2041 gataactccc ctattgttaa tgctcctact gttgctagag ccatcaaaaa gttctcatca
     2101 aatactcttc cttttgatat atttcttatt gctcttaaaa gcacatcacc acctactatt
     2161 acataggcaa ctataaatac tatattgcta aactgacttt cataacctgt agctgtttga
     2221 tatataccaa atatatatac aagtgctcca attataagtg gaattaattc tttcttattt
     2281 gtatcattta cagctcctga tttttcagta gttctccctt ttactttgtc agtagaccct
     2341 acttgtatat caagccctgg ctctgttgaa tttattattt cttttatttt atttataaca
     2401 tcatcctctt caaagttatt acttatattt actgtaagtt ttttatttac aaagtttaaa
     2461 ttagaagatt caacttcttt taatttagaa actttgttat taatctcttc tgcacaatga
     2521 gcacagttta atcctcctaa tataagctct tttttaattg atgttttact agctgcattt
     2581 tctttagaac ttatttgtat atcaagacct ggatctgttg aatctattat atctattatc
     2641 ttttctatag tagtatcctc attaaaactt tcctttatat ttactgtaag ttttttattt
     2701 ataaaattta aattggaaga tttaacttct tgtagtttag aaactttatt attaatctcc
     2761 tctgcacagt gagcacaatt taatcctcct agtataaatt cttttttaat tgaattattt
     2821 gcttccatat atattcactc ctctcattta tcatttataa gtctctctaa tatgatttaa
     2881 tccacaatca aatatctgac ttatatgact atcatctaat gagtaataca ctgtttttcc
     2941 ttctcttcta aactttacta atctagcctg ctttaatact ctaagttgat gagatattgc
     3001 agaatgagtc atatttaata aactcgctat atcacataca cacatttcat ttgcaaataa
     3061 tgcatataat atctttactc tagtagtatc cccaaatact ttaaataatt ctgctaaatc
     3121 atataacatt tcttcatctg gcatagttga tttagcctct gttactattt cttcatgtac
     3181 tatattacaa ttacaatcat ttatctcttc tctcattttt aatcctccat tattttaata
     3241 tatgaataac tgttcatatg ttcattatat gttatcattt ctaaatttgc aacaataatt
     3301 tttattaatt taatataaat agaatgcaca tattataaac ttttttaata tatatattat
     3361 tagaataagt ttttgtaaac ttttttatag ttttctagga ggtgcaagtt taatatgagt
     3421 aacaagaaaa aaaaggattt agatactagt tacatgcctt acttagaccc agcgaactat
     3481 gcagattata ttactaatga agaaattccc caagatgaat tgagaaatga ccctcaaatt
     3541 tctaatggtt atacaaaaat acctaataac cagaacataa ataacctata tcctaataat
     3601 gtaaatcatt atcctaaaag tagtaattct ccaaacaact tgcctaacac aaataataca
     3661 tccggaaata tgaattacaa tacatctgct acaaataata tgcctaataa catgaataat
     3721 aatacgggta tgcctaataa tatgtctaac aatatgaata gtaatatggg tatgcctaac
     3781 aatatgccta ataacatgaa tagtaatatg ggtatgccta acaatatgcc taataatatg
     3841 aatagtaaca tgggcatgcc taacaatgtg cctaataaca tgaatagtaa tatgggtatg
     3901 cctaacaata tgtctaataa tatgaatagt aatatgggca tgcctaacaa tatgtctggc
     3961 aatatgaata acaatatgta tggtaataca ggtatgccta ataacatgaa cagtaatatg
     4021 gggtataata tgaacaatac tatgggtatt cctaacttct catgtaatca aaatatgcct
     4081 cctaatgtac ttatgatgat accaggagtt atatgtcata atacaatgca aggtatgcct
     4141 gtagttatgc ctagtactat gcctcctaat atatatccta ctccttatgg ttctagtaat
     4201 atgtctgtac aaggtatacc acaagctact aatattgagg aatttgatga ggaagaaatg
     4261 taatatatat ttttttaagt aagttgtata aaacattaat aattgaccat aataataaat
     4321 gtattcctca taatattccc ccaatattat tataggtata gaaagttgac tgaatatgcg
     4381 cttattcggt caacagatat taacataatc taataagata aacatagaaa aagtcagata
     4441 aaatttaatt ttatctgact ttttcattta aaaatgctct cttgtgttgg tgattcagaa
     4501 tagtatggta ctcgtatttg agactaatat tggcaaacaa cataaagaaa aatataaatt
     4561 ttttataata aactgtataa aattttaata attgaccaca ataataaatg tattcctcat
     4621 aatattcccc caatattata gaaataaatt taagcgagat taaattcagt taatctcgct
     4681 taaataatgt ctaaatttat tattccaaaa aatcatcaaa atctaatgaa cctgattctg
     4741 caaaatcata taatgcattt tgctcaaaga aaaatttctc ttcaaattta atatagtcgc
     4801 tataattaga ttgacttatt tcattgatat aattgcaatc attttcgtta taagtaccaa
     4861 taaaaaactt atttcccatt aagtaatata tagctttcat atcattattt attatatata
     4921 cattttcttt tacatggtca ttattaaaat taaatctagt aaagaatata ccttcattca
     4981 tattactttt taacagaaat ggattttctc tataaaatac tcctgcaaat tcttcaggtg
     5041 aatttacact gtaaacactt acaaattcac ttttagaaat ctcatcaaat acctcaaaat
     5101 catacatagg ttctttatct gtcactaata gagaattaat tctaaaacca gtttcataac
     5161 acttacttat gcaaaaagca attttacata tataatatcc atcattatct tcatataaag
     5221 cttcacttat atatctgcct tgacctttat cacttaccac gtttttaagt aatgttccat
     5281 ttatattagt aatgtgcata tttgcaatct cgtcacttcc agaaaagtac tttaaacttt
     5341 ctctatccca tgctataaat ctcatggtca tatagtttat aaattcaact tcctcgtcaa
     5401 ctcttttaca tattttattg tataattttt ctatagttaa atctgtttta tagtttttta
     5461 taatatcaat atactcacat ttatctcctg gcaatagctt atcataataa agattcttat
     5521 taccaaaata agatactaaa aataaagatt catccttcgt taattcaact ctatctgaac
     5581 caaatcctcc catcaatctt tcttcttcca tataagcttc ttcttgtgtt gggttattta
     5641 aactcacata atccgctaat cctaatccct ctgcatctaa taaaaaatat tgacaaaagt
     5701 gattgttttc atcatctatc caatttatta taagacctaa actgcccata agtctagaat
     5761 ttgtagcctt tgcaaaatta aaattcatat agtcacatcc tttaaactct aaaatacttg
     5821 ttttttaata tataaattat tatacatata ttttaacaac ttagatacaa tttataatat
     5881 aatataagga aatgattaat tgaggtggtc ttatgaaaaa tatagcagct ttttttgata
     5941 tagatggtac tctttataga gactctctta tggttgaaca ttttaaaaaa ttaattaaat
     6001 acgatataat tgaccaaaaa aattggtata aacatgctag agacactttt atggattggg
     6061 ataaaagaca aggtaattat gatgattatc tattagaaat atgtgacctt tatgttgatt
     6121 cactaaaagg attagataaa acctgtatca actttacaag tgaccaagta attaaattaa
     6181 aagcagatag agtttataaa tacacacgtt caaggattga gtggcatcta aatcaaggac
     6241 acatagttat atttatatct ggtagccctg gatttcttgt tgaaaaaatg gcaaaaaaat
     6301 ataatgtaac cgattttcta ggaagtgatt atgtctttga aaacaatata tttacaggca
     6361 cagttattcc aatgtgggat tctataagta agaataatgc tataaacgat tttgttgtaa
     6421 agtatgattt agatttatca aactcgtatg cctatggaga tactaatggt gatataaata
     6481 tgctaaaaag agttggaaat ccaatagcaa taaatccaac aaaggaactt ttatctcaaa
     6541 tatcacttga tgaggaaatt tctaaaaatg ttgagataat agtagaaaga aaagatatta
     6601 tttattctct atctacagat gtaaatatag tggatattta atttatacta tctattttaa
     6661 aaacttatat tatatctaat atttatatct aacatataaa agctttgact aaaaatcaaa
     6721 gcttttatat gttgcactaa gaatatatta aatttagctt tatgctttaa tgtatattca
     6781 tatatatcat ttacacttat ctaaactaca atttcattaa aattaaatat aaaaatcaac
     6841 tattattttt taaatagcat ctttcttaat ctattattgt aata
//
LOCUS       DAEPHU010000131         6848 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 01A10CD0081
            SAMN05941466-rid12468953.denovo.132, whole genome shotgun sequence.
ACCESSION   DAEPHU010000131 DAEPHU010000000
VERSION     DAEPHU010000131.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941466
            Sequence Read Archive: SRR6291087
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 6848)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6848)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068158.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 22:43:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,892
            CDSs (total)                      :: 3,805
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 87
            rRNAs                             :: 8, 1, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 55
            CDSs (without protein)            :: 55
            Pseudo Genes (ambiguous residues) :: 0 of 55
            Pseudo Genes (frameshifted)       :: 21 of 55
            Pseudo Genes (incomplete)         :: 28 of 55
            Pseudo Genes (internal stop)      :: 16 of 55
            Pseudo Genes (multiple problems)  :: 8 of 55
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6848
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941466-rid12468953.denovo.132"
                     /strain="01A10CD0081"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            251..1078
                     /locus_tag="KR231_003601"
     CDS             251..1078
                     /locus_tag="KR231_003601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AIM24 family protein"
                     /protein_id="HBH0005927.1"
                     /translation="MDLSKKVKILENASDGKSEFEILEFEKLEGASSPLMAMGLYFAR
                     EAGLKARQIKIKLNNSSIKTEAGALYYYKGNISSETKIGGVGGLFKKGISGALTNESM
                     MKPVYKGTGEVYLEPSFRHYLFMSLDNDSIIVDKGLFYCCSDTIEVKAFTQKNFSSAL
                     LGGEGFFQIELSGTGVIVLECVVPQSEIVEYELKNGEELKVDGNFAIARTSGVNFSVT
                     KSDKSLIGSALNGEGFLNTFTGSGTVWLAPTQVMYEKLSFGAMPTNDNMNNKVSKQK"
     gene            2078..2541
                     /locus_tag="KR231_003602"
                     /pseudo
     CDS             2078..2541
                     /locus_tag="KR231_003602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861860.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
     gene            complement(2808..3452)
                     /locus_tag="KR231_003603"
     CDS             complement(2808..3452)
                     /locus_tag="KR231_003603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBH0005928.1"
                     /translation="MFGQSFQNCLVLIKENFKLSTLTNLICSIILLCMIPLIQGVANL
                     DRISTAICLENYVAIIGIVMLVPVFSLEQSKEIDEIVSSKALSQVIVQLIRILMSIIG
                     IVVLIIGFVNVLIYLGCNFPVVEYIIGSFASAMFIGSLGMFFSNLFNNTIIGYMISIG
                     YLILNMMTKGKYVGKFFIMSMSQGSFDEKYWLILGSVVLIIASLLIKPVKRKIR"
     gene            complement(3382..4671)
                     /locus_tag="KR231_003604"
     CDS             complement(3382..4671)
                     /locus_tag="KR231_003604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBH0005929.1"
                     /translation="MNLFIKECKNILKSMIYYIFIVVLVFFYISQLGSSVSNDVSKNI
                     PNDGNPLVAPQKVENIEEYYSVHNQYPYGQKESMKTEKVIPNATINLIREYQKNTYTT
                     YPTGVVKYIKLDQNKTKTIEKYIEEITGKSISEINSLWKTDESIKIDYSKVSLERFEE
                     IMQRVDDILGGGSAYAFDKLQRFGVVPVTYDEAMKNYNYTIQKDKVSNGYARIFCDYI
                     GIVLSIFPVFVAVFMSLKDKRSRMREIIYSKQVSSCKIVLSRYFALVFMMILPVLILG
                     MKDLLPLIFFAKDKGISIDNLAFIKYTLWWILPTLMIVTAVGMSITILTDTPVAIIVQ
                     LIWWLYSINSTGLKGDYSTMGLMIRHNSVLNGDIIIQNFNQIMINRIVISLGALVLVL
                     LAIFLYEQKRRGNLDVWAKFSKLFSSNKRKLQIKHFN"
     gene            complement(4668..5540)
                     /locus_tag="KR231_003605"
     CDS             complement(4668..5540)
                     /locus_tag="KR231_003605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH0005930.1"
                     /translation="MEMKIAVSNLSKRFGKKQALDNINLEIDSGMFGLLGRNGAGKTT
                     FMRILATLLSKTEGSIHMCGVPIENTKEIRNMVGYLPQDFSMYPNMTVYKAMDYLAVL
                     SDIPLRKRRKIIAKLLSKVNLTNYQNVKVKSLSGGMNRRLGIAQALIHNPRVLIVDEP
                     TAGLDPEERIRFRNLLCEIANDRIVILSTHIVGDIEATCENVAILNSGKVIYNGSTEA
                     LAKLAEGKVYSIEVDKKDIENIKSRFIVIGMLTHGGKAILRIISDDKPFETAVNCNPT
                     IEDGYMLIMGGDNI"
     gene            complement(6069..6560)
                     /locus_tag="KR231_003606"
     CDS             complement(6069..6560)
                     /locus_tag="KR231_003606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfbM family protein"
                     /protein_id="HBH0005931.1"
                     /translation="MGMIGCYTKISEENVFKLQQAEENLQDFVFEDANENSTINIDKA
                     WHAIHFTLTGCPFGGDDDNIFSKLVLSGNILMEIDGEFPVMLITANDVKKLSKAMNSL
                     EEQAFRKRFNINEMLENNIYPVMNDESEDDFFEYVWANLIELKKFIQEASNDGLAVIF
                     FIM"
BASE COUNT         2492 a          943 c          812 g         2601 t
ORIGIN      
        1 ctatcttcta aataatttta acatgcccat aaaatataat acccacaaat gataaataat
       61 actcaaaatg tctattgaaa taactataca tccttaaata acttaactta aatctaaaca
      121 tttcaaaaac ttcttaaaaa tatgtaaaaa tttgatgata aagtagcgat tttttcaaaa
      181 aaaatgtaat atagagttat atcttataat attttagaga taaattttat catagtgggg
      241 agaaatttgt atggatttaa gcaaaaaagt aaaaatttta gaaaatgcat cagatggcaa
      301 aagcgaattt gagatattag aatttgaaaa acttgaggga gcttctagcc cattaatggc
      361 aatgggatta tattttgcta gagaagctgg tttgaaagct agacaaatta agataaaatt
      421 aaataattca tcaataaaaa cagaagctgg tgcattatac tattataaag gaaatatatc
      481 ttctgaaact aagattggtg gtgttggagg tctttttaaa aaaggaatat caggagcact
      541 tactaatgaa tcaatgatga aacctgtata caaaggtact ggagaagttt atttggaacc
      601 ttcttttaga cattatttat ttatgagtct tgataatgat tctataattg ttgataaagg
      661 attattctat tgttgctctg atacaataga agtaaaagca tttacacaaa agaacttctc
      721 atctgcttta cttggtggtg aaggcttctt ccaaatagaa ttaagtggta ctggtgtaat
      781 cgttctggaa tgtgttgtac ctcaaagtga aattgtagag tatgaattga aaaatggtga
      841 agaattaaag gtagatggta actttgcaat agcaagaaca tctggtgtta atttttctgt
      901 tacaaaatca gataaatctt taattggttc tgctttaaat ggtgaaggtt tcttaaatac
      961 atttactggt agtggtacag tttggctagc tccaactcaa gtaatgtatg aaaaactaag
     1021 ttttggagca atgcctacta atgataatat gaataataaa gtttctaagc aaaaatagtt
     1081 gttttataaa tatttattaa atcattattg attttataaa gtcactataa attttattag
     1141 attattataa aatcagagtg tggaaatatt tatgtgtatt ctttaaataa aaatttccac
     1201 attctgtaaa gttattatac ttgatatata aaattcaatt taggaacata gtctaacatt
     1261 tataaacata ttaaggtaat gatttctctt ggtagttatt ctcatatctt attctttgat
     1321 tatatttatc ttattcctag cccttatgtc atattatatt tcttatctta ttatttataa
     1381 ttagcattaa cttatctaaa atcttgtatt tttttaatag taaagtttac atctatatta
     1441 atttcataaa acaatcaagg tagtcaagag attcaacttt atttgatttt aaaaatttaa
     1501 gtgaatttgt tcttatacac acctttttaa aattatatct gtagaaaata tcatttagag
     1561 ctataattaa attaacttat taaattttag aaaatttatt aaaaaatata agttaaatta
     1621 atatttttaa agattctttt ttgtaactac tagaacacta atttagtagt tattgtatct
     1681 ctaaagttta agcatggata gatatacatt tgataatttg cctataattt acctactact
     1741 tggattattg gagcaaatac aatatattaa taataagttc ctaaaaccaa taaattaact
     1801 aatacacata aagatattga tgttgattat acaactataa gaaacggatt taacagaatt
     1861 taatcaagct aagaaattat atatatcgtg atgtttttga attagaaggt gattcaaaat
     1921 tagtttatag tcttctgtga atccaataaa aagtacaggg tacaagaatt gttagtaaaa
     1981 tttttaaaga ttttatggat aaatataaat agttttactt attttctaaa actttaaaat
     2041 accattaatt accttaaata ttttaatagg aggacatatg aatttaaata aagttaaatt
     2101 tactgaagaa catgctattg aagttactaa ttggaaatat gaaggtaaat attcaatata
     2161 caatctacct ccatgggagg aaattaaaaa gaagaatttt tcactagcaa aagaagataa
     2221 aagaaaaaat tttataagtt ttataaatga caataaagaa ttgataggtt ttataaactt
     2281 attagatgaa ggaagctctg tattctttgg tattggttga aaccgaatta ttgtggaatg
     2341 ggaattggta aagaaataat tagcctagga ttacaagaat gtagaaataa atatagtact
     2401 aaaccaattg tattaaatgt aagaacctgg aacatgagag ctgtaaaatg ttatgagtct
     2461 caaggattta aaatagttga gactaaggta caaaaaacgc atttaggaga tggagaattt
     2521 tttgttatga ggtatcaata gtttataaca atagtcctat tgttaataca acaattaaaa
     2581 tgaaaaaata catatgtgta ggtcatagca ataagtgtct ttgaaatata aatttgagag
     2641 cttttgataa aattcggtat acatatatat tttatactac ggatatataa atctatctac
     2701 atacataaag agattgtaag taggtttgtg tatataaaaa tagatttata tttcataaat
     2761 gtacttttta tttgcattac ctttatttta tctaagctct cattttatta tctaatcttc
     2821 ctttttactg gttttattaa gagagatgca attatcaaca caacacttcc aagtatcagc
     2881 caatatttct catcaaaact accttgactc atagacatta taaaaaattt tccaacatac
     2941 ttgcctttag tcatcatatt taaaattaaa tatcctatag atatcatata acctatgatt
     3001 gtattattaa ataaatttga gaaaaacatt cctaaacttc ctataaacat agctgatgcg
     3061 aaacttccaa taatatactc aactactgga aaattacatc caagatatat taaaacattt
     3121 acaaaaccta tgattaatac cactatacct ataattgaca tcagtatcct aattaattgt
     3181 acaataactt gagataatgc ttttgaagat actatctcat caatttcttt tgattgctct
     3241 agcgaaaata caggtaccaa cattactatc cctattattg caacataatt ttctaaacat
     3301 atagctgttg aaattctgtc taaattagct actccttgta ttagaggaat catacatagc
     3361 aatataattg aacatattaa attagttaaa gtgcttaatt tgaagttttc ttttattaga
     3421 actaaacagt tttgaaaact ttgcccaaac atcaagattc ccccttcttt tttgctcata
     3481 taagaatata gctaacaaaa caagcaccaa tgctcccaaa cttatcacaa ttctattaat
     3541 cataatttga ttgaagtttt gtataataat atccccattt aatacactat tatgtcttat
     3601 cattagcccc attgttgaat aatcaccttt gagtcctgta gaatttatac tgtaaagcca
     3661 ccaaattaat tgcacaataa ttgctactgg tgtatctgtt aatatagtaa tactcattcc
     3721 tacagctgta actatcataa gagttggtag tatccaccat aatgtatatt ttataaatgc
     3781 taagttatca atagatatac ctttatcttt agcaaagaaa atcaaaggaa gtaaatcttt
     3841 catacctaaa attaatacag gcaatatcat cataaagaca agtgcaaaat atcttgataa
     3901 aactattttg catgaagata cttgttttga ataaataatc tctctcattc ttgaacgctt
     3961 atctttaagt gacataaaaa ctgccacaaa tactggaaat atacttaaaa ctatacctat
     4021 ataatcgcaa aaaattcttg catacccatt actaacttta tctttttgta ttgtatagtt
     4081 gtaattcttc atagcttcat cataggtaac tggaactact ccaaatcttt gtaacttgtc
     4141 aaaagcatat gcagaccctc ctcctaaaat gtcgtctact ctttgcatta tttcttcaaa
     4201 tctttcaaga gatactttag aataatctat ttttatactt tcatcagttt tccaaagtga
     4261 atttatttcg ctaatacttt taccagttat ttcttctata tatttttcta tggtcttcgt
     4321 tttattttgg tctaatttta tatacttaac tacccctgtt ggatacgttg tatatgtgtt
     4381 tttttgatat tctctaatta ggtttatagt tgcatttgga atgacttttt ctgttttcat
     4441 agattctttt tgaccatatg gatattgatt gtgtacagag taatattcct caatattctc
     4501 tactttttgt ggagcaacta atggatttcc atcattagga atatttttac ttacatcatt
     4561 tgaaactgaa cttccaagtt gagaaatata gaaaaaaact aaaactacaa taaaaatata
     4621 atatatcata ctctttaata tatttttaca ttcttttata aatagattca tatattatct
     4681 cctcccatta taagcatata gccatcttca atagttggat tacaatttac tgctgtctca
     4741 aaaggtttat catctgatat aatcctaagt atagcctttc caccatgagt caacattcct
     4801 ataactataa atctactttt tatattttca atatcttttt tatctacttc aatactatat
     4861 actttccctt cagctagttt tgctaatgct tctgttgagc cattgtatat gacttttcca
     4921 ctattcaata tagctacgtt ttcacatgta gcttctatat ctccaacaat atgtgtagat
     4981 aaaataacga ttctatcatt tgcaatttcg catagtaaat ttctaaatct tatacgttct
     5041 tctgggtcaa gacctgctgt cggctcatct actattaaaa ctctgggatt atgaattaat
     5101 gcttgtgcta tcccaagcct tctattcata cctccagata aagattttac tttcacattt
     5161 tgataattag taaggtttac tttgcttaat aactttgcta taatttttct tctttttctt
     5221 agtggtatat ccgataaaac tgctaaataa tccattgctt tatatactgt catgttagga
     5281 tacattgaaa agtcttgtgg caaataacca accatatttc taatttcctt agtattctca
     5341 ataggaactc cacacatatg tattgaacct tctgtttttg ataataaagt ggctaaaatt
     5401 ctcataaatg tggtttttcc tgctccattt cttcctaaaa gaccaaacat accactgtcg
     5461 atttcaagat ttatattatc aagagcttgt tttttcccaa atcttttact aagattggat
     5521 actgctattt tcatttccat atataaatac acccccagaa acaattttat agaattttat
     5581 ttttataaat ttttactgta ttttcataat aaattctaaa acttaagata ttatttataa
     5641 atttctaaat tttttctaaa gattttaatt tttctgtttt taattaaatt aaagtatctt
     5701 tgtttctgaa attttttaag tttatgaagt tataatttaa tatatattta ttttatttgt
     5761 gagtctattt ttatatataa tgaaaaatgt gataagtatc caaaagaatt actggatata
     5821 ataggatagg gtatttagcc ttttaagata aataaaaata tctgcaacta tatattgcaa
     5881 aaatttaaaa ctaatttata tatgctaata taaatattta taaagacata agacaaattt
     5941 acctacagat ttaaatttaa cttatatatt ttaaaaggct aatataatat gtattttctt
     6001 ctatacaatc aaaaggcttc atatctaaga tatgtgatga cactaatatt cacaattttt
     6061 agtaattatc acattataaa aaatattaca gctagtccat cattagatgc ttcttgtata
     6121 aactttttaa gctcaattag atttgcccat acatattcaa aaaaatcatc ttcactctca
     6181 tcattcataa caggataaat attattttct aacatctcat taatattaaa tctttttcta
     6241 aatgcttgtt cttccaaact gttcattgct tttgatagtt tttttacatc atttgctgta
     6301 atcaacatga caggaaattc tccatcaatt tccataagta tgtttccact tagtactaat
     6361 ttgctaaata tattatcatc atctccacca aaaggacaac ctgtcaaagt aaagtgaatg
     6421 gcatgccatg ctttatcaat attgatagta ctattttcgt tggcatcttc aaaaacaaaa
     6481 tcttgtaaat tttcttctgc ttgctgtaat ttaaaaacat tctcttcact tattttagta
     6541 taacatccta tcattcccat aattacattc ctcctaagta gcgttttttt aattgtaact
     6601 tataattaaa cttagttaca ataaaatata ttgagaaaag tattatttca tcttaaattt
     6661 aaatacctat attatcaact aaaattctgt gtttatagcg taagtattat tttttcctaa
     6721 aaattaaatg aatcagaggt tctataggca atattgacta taaataagaa ctattacttt
     6781 ttaaaaaaaa tttaagaaat tatactgtag aatcatgctc tacttattag ctttaaataa
     6841 aaaataaa
//
LOCUS       DAEPHU010000132         6725 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 01A10CD0081
            SAMN05941466-rid12468953.denovo.133, whole genome shotgun sequence.
ACCESSION   DAEPHU010000132 DAEPHU010000000
VERSION     DAEPHU010000132.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941466
            Sequence Read Archive: SRR6291087
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 6725)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6725)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068158.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 22:43:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,892
            CDSs (total)                      :: 3,805
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 87
            rRNAs                             :: 8, 1, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 55
            CDSs (without protein)            :: 55
            Pseudo Genes (ambiguous residues) :: 0 of 55
            Pseudo Genes (frameshifted)       :: 21 of 55
            Pseudo Genes (incomplete)         :: 28 of 55
            Pseudo Genes (internal stop)      :: 16 of 55
            Pseudo Genes (multiple problems)  :: 8 of 55
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6725
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941466-rid12468953.denovo.133"
                     /strain="01A10CD0081"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            complement(860..1420)
                     /locus_tag="KR231_003607"
     CDS             complement(860..1420)
                     /locus_tag="KR231_003607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan-binding protein"
                     /protein_id="HBH0005932.1"
                     /translation="MLKKLKKMLLITCCLFMMSSTAFAETQNSEGKSFTISGYTFMYE
                     NAPQEIKDKYKENCLDIGVEPQPNDEIFITPSELKTYSNIDMYSARSSSFTVTYHYSY
                     YKVTGDKNYTVNTSTIVKYGNSGNPVHLVQLLLKKVGYALEVDSQFGNTTLSKVKSFQ
                     GSYGLTVDGIVGSATWKKFASATNLD"
     gene            complement(1466..2449)
                     /locus_tag="KR231_003608"
     CDS             complement(1466..2449)
                     /locus_tag="KR231_003608"
                     /inference="COORDINATES: protein motif:HMM:NF017390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase M56"
                     /protein_id="HBH0005933.1"
                     /translation="MSNLILTDILRTSITSSLVICFLLLLRTTIFRIFNKGFNYYIWL
                     IVIVRLLFPFSYFTYTISDSKFQYKPILNEVDYSNTVLIIYLTIVILLAIYRFIKYLK
                     FKSLVIDLSYDIENLEINNLYNNLLKELNIEKHIKLKYTYEINTPSFFGLFDNYILLP
                     PHNYNLNELHWILKHELIHYKSKDLYIRYLVLFLKCVYFFNPFIYLLDRIIYHSCELH
                     CDEVVLKGCSLENIKSYANTILDSIERSSRDSNNYTTGLHRKSNFEKRVYDMFKNKGK
                     SGILIALILCLLSSFTYFKFDSIISKPINHSLDAPLPVNTGKEKSFTITID"
     gene            complement(2462..2824)
                     /locus_tag="KR231_003609"
     CDS             complement(2462..2824)
                     /locus_tag="KR231_003609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
                     /protein_id="HBH0005934.1"
                     /translation="MIEKIPRAELKVMMLFWDTDKVLTSRDIVNIMSEEWKQTTTLTL
                     LSRLSKRGFLEPTKKPTHTTYKILIDKKSYLEFATSDFVKNVHNDSIVSLVDSVNKEK
                     IGKDELASLRAFIKKLKK"
     gene            4067..4714
                     /locus_tag="KR231_003610"
     CDS             4067..4714
                     /locus_tag="KR231_003610"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0005935.1"
                     /translation="MNKKLEKPFVYKREYDLTGYDVEILQKYELEQAIYVYVGSSCAY
                     NMRARSSKWRYHIRTNNKSICCNIKNFIHNLELFYKMELKLSDNIINDKLYYSNIAEF
                     EEFETLEKAREVESTIISQYQFLDSINHMLKQKIILLSNKDSVLNITKNGNTNYLKVK
                     NKYIEKHKNKPIMRYHINCQFNTDGSVKSITQEFEPILELNKKNTLSRPSRVFLK"
     gene            4989..6626
                     /locus_tag="KR231_003611"
     CDS             4989..6626
                     /locus_tag="KR231_003611"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0005936.1"
                     /translation="MEQLDSKYKLKKFLMAVFRDGIGQGNNLIDNEYVRVFQNNKSNS
                     KQLELGEEFKEYSKTTFFKNIDDIVEFTFAKNIYYENTFFNLCTTDGKAGTNENLINR
                     YALGFDFDKKELGQGFNYKDIINLFTKIGLHYHILVDSGNGFHVYVLINKTNNIKLVS
                     EVTNTLINKLGADKQANLSTQVLRVPYTYNIKNTTKQVKIIHQDKNIYRYDIEKLAKK
                     YCKDVKTVGNTNTKYILDSKLPNCIVDILKNGSKDGHKNLDLQKIVVTLRLRNKSLSQ
                     VISVAREWNYISQNSLSNSELEYQVKYMYEKLKTVNFGCTGCEFNSDCWNKIESDFIY
                     SDEDTLFNMPHKHSKDLKYKNRKGVKIMTGNQLFIYNVLLNNKDRELNIDDIMELITY
                     KRKKKVKNIVMSEKTLRETLKELQHNDYITKTKGVTKLGIKDTYNVKEVRCNIDKQYT
                     ISYFVTMAVIWGIISTEELRLYTHMRYKQDLLVKDDKIKGNILRINQEELAKDLGVTQ
                     QRISNMIESLLDTKILDVWETKINDRGFMYYTYRLNK"
BASE COUNT         2750 a          701 c          945 g         2329 t
ORIGIN      
        1 aaaaaaaaaa tggcatcaaa gtattgaaat taagccgttt taaaaatttc ttttggtaaa
       61 ataattgtac atatatatgt agtatatata tatatgtttt ttagagaatg tataactaga
      121 atatagagct agaatataga gaatgtataa ctagaatata gagctagaat atagagaatg
      181 tataactaga atatagagct agaatataga gaatgtataa ctagaatata gagctagaat
      241 cctaattagt aggtgctttt ttaaaacaag ttaaaaatca aaaatagtat tagtaagcat
      301 tggaaatgct agattctaaa atagaaaagt aaaaaattgg tgcactatct aaacttatct
      361 atatcgcttt ttccgtcgtt tggttctcta gttacgatac aggggatatg cttatattga
      421 gttatagtac taatcagtgc ttaatatagt taataaaatt atagttacca tagtttagta
      481 actatgatgt atgttagtta gaaacttgca tttcatgagt tgtaatatct taaagtcagt
      541 agttttgatt ttaaaatatt aattgcactg ttacaaatga ctttattaat aaaaaattag
      601 gcagcttaaa aaaagtttag aataaatttg ctaggctttg ctaagctatt cttttaaaaa
      661 taactttaca aaacaaacaa ataaggactt ataaatatag ataaaaaaag aaaattgaaa
      721 aggattatag agacttacaa ggctttaaat atatattctt aattgtaaaa ttatgtaatt
      781 aaaatattta ctttattata aaaagacatg ataaacttat tatcatgtct tttgttaaac
      841 ttatttatat gtaaaaattc taatcaaggt ttgtagcaga tgcaaatttt ttccatgttg
      901 cactaccaac aattccatct accgttaagc cataactgcc ttgaaaactt ttaactttgc
      961 taagtgtagt gttcccaaat tgactgtcta cttctaaagc atatccaact ttttttaata
     1021 gcaattgtac taaatgaaca ggatttcctg aatttccgta ttttacaatc gtagaagtgt
     1081 tgacagtata gtttttatct ccagtaactt tgtagtatga ataatgataa gttactgtaa
     1141 atgaacttga cctagctgaa tacatgtcta tgttgctata agtttttaat tcactagggg
     1201 taataaaaat ttcatcatta ggttgtggct ctacacctat atccaaacaa ttttccttat
     1261 atttatcttt tatttcttgt ggtgcatttt catacataaa tgtgtaaccc gaaatagtaa
     1321 agctttttcc ttcactattt tgtgtttctg caaaagctgt gctactcatc ataaataaac
     1381 aacaagtaat tagcaacatt ttttttaatt tttttaacat aattcctccc tataattttg
     1441 aatatatttg aataccagca aatatttaat ctattgttat agtaaaagat ttttctttgc
     1501 ctgtattaac tggcaatggt gcatctaagg agtgattaat tggctttgat ataattgaat
     1561 caaatttaaa atatgtaaat gatgacaata agcataaaat caatgctatt aaaataccac
     1621 tcttaccctt atttttaaac atgtcataaa ctcttttttc aaaatttgat tttctgtgta
     1681 atccagtagt gtagttattt gaatctcttg aacttctttc aattgaatct aaaattgtgt
     1741 tagcataact ttttatattt tcaagggaac aaccttttaa tacaacttca tcacaatgta
     1801 attcacagct atgatatata attctatcaa gtagataaat aaaagggtta aagaaataaa
     1861 cacactttaa aaataaaacc aaatatctaa tgtataaatc tttacttttg taatgaatta
     1921 attcatgttt tagaatccaa tgcagttcat ttaaattata attgtgtggt ggcaaaagta
     1981 tataattatc aaataatcca aaaaatgagg gcgtattgat ttcataagta tattttagtt
     2041 taatgtgctt ttctatattt agttctttta ataaattatt ataaagattg tttatttcaa
     2101 gattttcaat gtcatatgat aagtcaataa ccaaactctt aaactttaaa tattttataa
     2161 acctataaat tgcaagtaaa ataacaattg ttagatatat tattaatact gtatttgaat
     2221 aatcaacttc attcaaaata ggtttgtatt gaaatttaga atcagaaata gtataagtaa
     2281 aataagagaa tggaaaaagt aatctaacta ttacaattag ccaaatataa taattaaaac
     2341 ccttattgaa aattctgaat atagttgtcc ttaaaagtag cagaaaacaa ataactagac
     2401 tacttgtgat actggttctt aaaatatctg ttagaattaa attagacata tatagtacct
     2461 attatttctt aagttttttt ataaaagctc tcaaagatgc caattcatct tttcctatct
     2521 tttctttatt aactgaatca actaaactta caatagaatc attatgtaca ttctttacaa
     2581 aatcagatgt tgcaaattct aagtagctct ttttatcaat caaaatttta taagtagtgt
     2641 gtgtaggttt ttttgtaggc tctaaaaacc ctcttttaga aagcctagat aatagtgtaa
     2701 gtgttgtcgt ttgtttccat tcttcactca ttatatttac aatatctctt gatgtcaata
     2761 ccttgtcagt atcccaaaat agcatcatta ctttaagttc agcacgtggt attttttcta
     2821 tcataatatg ttcctccatc ctaatgttaa aaaaattaat aaatgtaatt ttattctatt
     2881 gaaatagagt aggacagtca attgtttttt gattaatgat ttacatatgt agagtaaatt
     2941 aaaagaagta tatcacttga aaagttttac atacgtagag catttttatc aaatctctta
     3001 atttttttaa ttgaattata tatgtgaata taagagtaaa tcaacttaaa acatgcaaaa
     3061 aattaatatt tactgacatg caactgacaa atcaacaaaa ataggaattg ataaaataag
     3121 tgtatatatt gaaattgcta taatacatac aaaaatggca taaaatacta atttttatgt
     3181 ccttttctac tgacatgtaa aaaagtcttg taagtattgg aattactaga ttacataggt
     3241 tttagatgca aaattgtcgt tttgtaaaaa aggctactaa aatttataaa aacaattatt
     3301 aattgatata aattatcaca aaaaaagaca tctatttcta tgaaaaaaaa attttcgtct
     3361 gcatgtaaaa atagctatag taatgcgtac gaatgttcta ttattacaga attatttgta
     3421 tgtaaattat attgaaaata tctatcagaa ttagaatttt atatggataa aacagaacta
     3481 tcaaatagga gtatatagta aagatttata taatatgatg acctcgtaca agcctgtaag
     3541 agccgtttaa aagttgcttt agtattaatt atctttgaaa atttaaaata ggtttaaatg
     3601 gcttgttaaa tatgatgtat tactattatg tatagggggg tagttatgta gttacatgtt
     3661 gttttaaaaa ataaatttaa ctatagttct ttcacttcca cattacaaaa aataaattga
     3721 gtgtgtatgt ttttaagtaa aaatgatgtt taaatattga aaaatagaga tatagtgtat
     3781 gtaaaattta gaatagtgta tgtaatttta ggcataaaaa tatgtgatta aaccttaaaa
     3841 accaggaata tagtgtatgc atttttaaaa ataaaaattg taaccttttt gtaatctttt
     3901 attaaaatac ttactttaag tctaaaaatt aggggagatg taaggatttg ggaaaaatag
     3961 aagatgttat aatcataaat atggtattcg taggcttaaa gtcaaaaagg aggtgaaata
     4021 taaatagatt tttagctaaa ttaagtaaga aataggagga gatttattga acaaaaaatt
     4081 agaaaaacca tttgtatata agagagagta cgatttgact ggatatgatg ttgaaatttt
     4141 acaaaaatat gagttagaac aagcaatata tgtttatgtt gggagtagtt gtgcatataa
     4201 catgagagct agaagtagta aatggagata ccatataaga acaaataata agtctatatg
     4261 ttgtaacatt aaaaatttta tacataactt ggaattgttt tataaaatgg aattaaagtt
     4321 gtcagataat attattaatg ataagctata ctatagcaat atagcagagt ttgaagaatt
     4381 tgaaacacta gaaaaagcta gagaggtaga aagtactatt ataagtcaat atcaattttt
     4441 agattctata aatcatatgt taaaacaaaa aataatttta ttgagtaata aggatagtgt
     4501 gttaaacata actaaaaatg gaaatacaaa ttatttgaaa gtaaaaaata aatacataga
     4561 aaaacataag aacaagccaa taatgagata ccatatcaac tgtcaattca atacagatgg
     4621 aagtgtcaaa agtattacac aggagtttga accaatattg gaattaaaca aaaaaaatac
     4681 cctaagccga ccaagcagag tatttttaaa ataatatttt aagataacaa caaaatgaga
     4741 taatactact agacaatgac aactcaacta ccaattgagt ttatggagct accaactcca
     4801 atatcggtct aactgattaa gtatctgtag ttatataata atattgctat caattttagc
     4861 atcttaacaa tattattata catactaagc taaaattatt caatagttgt aaaagttgat
     4921 tagtcaataa gtatatattt aatgtagtgt tatctcttaa aaaaactaga taaggagata
     4981 ataaatatat ggaacaatta gattcaaaat ataagttgaa aaaatttcta atggcagtat
     5041 ttagagatgg tataggacaa ggaaataatc ttattgataa tgaatatgtt agagtatttc
     5101 aaaataataa aagtaatagt aaacaattag aactcggaga agaatttaaa gaatatagta
     5161 aaacaacttt ttttaaaaat atagatgata tagtagaatt taccttcgca aaaaatattt
     5221 attatgaaaa tacatttttt aacctatgta caactgatgg aaaagcagga accaatgaaa
     5281 acttaataaa tagatatgca ttaggatttg attttgacaa aaaagaatta ggacaaggtt
     5341 ttaattataa agatataatt aatttattta ctaagatagg attacattat catatcctag
     5401 ttgatagtgg aaatggattc catgtttatg tgctaattaa taaaactaat aacattaagt
     5461 tagtatcaga agttacaaat acattaataa ataaattggg tgcagataaa caagcaaatt
     5521 tatctactca agtattaaga gtaccttata catataatat taaaaatact actaaacaag
     5581 taaaaataat acaccaagac aaaaatatat atagatatga catagaaaag ttagctaaaa
     5641 aatattgcaa agatgtaaaa acagtaggta atactaatac aaaatatata ttagatagta
     5701 agctaccaaa ttgtatagta gatattttaa aaaatggtag taaagatgga cataaaaacc
     5761 tagatttgca aaaaatagtt gtgactttaa gattgaggaa taaaagttta agtcaagtaa
     5821 tatccgttgc tagagaatgg aactatatat cacaaaatag tctttcaaat agtgagctag
     5881 aatatcaagt caagtatatg tatgagaagc ttaaaacggt taattttggt tgtacaggtt
     5941 gtgagtttaa tagtgattgt tggaataaaa tagaatcaga ttttatatat agtgatgaag
     6001 atactttgtt caatatgcca cataagcact caaaggattt gaaatataag aataggaaag
     6061 gggttaaaat aatgactggt aatcaattgt ttatctataa tgtgttactt aacaataaag
     6121 atagagaatt aaacatagac gatataatgg agctgataac ctataaacgt aagaagaaag
     6181 ttaaaaacat tgttatgagt gaaaagacat taagagaaac attaaaagaa cttcaacata
     6241 atgattatat tacaaaaaca aaaggtgtta caaagctagg aataaaagat acatacaatg
     6301 taaaagaagt tagatgtaat atagataaac aatatactat tagttacttt gttaccatgg
     6361 cagtaatttg gggaataatt tcaactgaag aattaagatt atatactcat atgagatata
     6421 agcaagattt attggtcaaa gatgataaaa taaaaggaaa tatattaaga attaatcaag
     6481 aggaattagc aaaagattta ggagtaacac agcaaagaat ttcaaatatg atagaatctt
     6541 tattagatac taaaatttta gatgtatggg aaactaaaat aaatgataga ggatttatgt
     6601 actatacata tagattaaac aagtagattt ttgataggat tagaattgat tttctagtcc
     6661 tatttttatg caaaaaaact aattaataaa aatttctttt ggtaaaataa ttgtacgaga
     6721 attgc
//
LOCUS       DAEPHU010000133         6701 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 01A10CD0081
            SAMN05941466-rid12468953.denovo.134, whole genome shotgun sequence.
ACCESSION   DAEPHU010000133 DAEPHU010000000
VERSION     DAEPHU010000133.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941466
            Sequence Read Archive: SRR6291087
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 6701)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6701)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068158.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 22:43:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,892
            CDSs (total)                      :: 3,805
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 87
            rRNAs                             :: 8, 1, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 55
            CDSs (without protein)            :: 55
            Pseudo Genes (ambiguous residues) :: 0 of 55
            Pseudo Genes (frameshifted)       :: 21 of 55
            Pseudo Genes (incomplete)         :: 28 of 55
            Pseudo Genes (internal stop)      :: 16 of 55
            Pseudo Genes (multiple problems)  :: 8 of 55
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6701
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941466-rid12468953.denovo.134"
                     /strain="01A10CD0081"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            67..480
                     /locus_tag="KR231_003612"
     CDS             67..480
                     /locus_tag="KR231_003612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0005937.1"
                     /translation="MSKSELGVKANLVSELMMLSYFFIDLLLQKFIFKGEGIWFTFII
                     LLAFWVCNLMYNKKYNDLVDEASKLMLLKVDQIASKIMLYSMFVIAVLFSVNHTRALD
                     ISNLDIGIMLLAVLFIQSLSKLILYIYFDKKGICN"
     gene            550..966
                     /locus_tag="KR231_003613"
     CDS             550..966
                     /locus_tag="KR231_003613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0005938.1"
                     /translation="MSKSETGVRSKLILELLVITYFFIAVLATKYIFKGPSTASLPGL
                     SWLIVFGCYSIYNKKYNDLVDESSEFILSKVNKIAIKIMIYSIVIISIFFATPYTSNI
                     NISNLDTGIILIAVLFIQSLSKLVLYIYFDKRGICN"
     gene            967..1179
                     /locus_tag="KR231_003614"
     CDS             967..1179
                     /locus_tag="KR231_003614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBH0005939.1"
                     /translation="MAILMKTKIKEYREKLLMTQNELAKLVGVRRETIVHLENGKYNP
                     SLKLAMDIAKVFDTTVENLFEFIEEE"
     gene            2223..3056
                     /locus_tag="KR231_003615"
     CDS             2223..3056
                     /locus_tag="KR231_003615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HBH0005940.1"
                     /translation="MVIKKVFNNNVVFARDNSGQEVILMGKGIGFNKFTKDLVEIDKI
                     EKKFIFNNEESLSELHSLLDRIPLKDVELVSEIIQMGREELGDNLNDSILITLSEHIS
                     YMLKRMDEGLVFQSPLQWEIRQIYPNEYNFSKKAVEYLRKKLDKNIPDSEIAFITIHF
                     ANAQLETKDMQETLLLTKIIDNVLDIIKYHYGIEINEYSFDYTRFISHLRCFIKRQLS
                     GENTNVDTSLLDIIKMKYKSDYNCAKKVKNFLEKTYKWKISENELLYLTLHLNRLSNI
                     K"
     gene            3182..5023
                     /locus_tag="KR231_003616"
     CDS             3182..5023
                     /locus_tag="KR231_003616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HBH0005941.1"
                     /translation="MKFERESEEIIKYVGGKENIISLVHCATRLRFKLKDTSKTNKEE
                     LLKMKDVLSVVNSGGQYQVVIGNKVTDYFETIIKKAVLQGQNTEEQGEKVSIVSKIFE
                     SISGAFSPLIPALAGAGMIKALLTILTTMKWMSDTSSTYAILSAAGNAVFYFLPIFLG
                     ITLAIKLSANPYVGGVIGAALLDPNFTALIGAKGGANFFGMPVTAIDYSFGVFPIFVA
                     IFIYYYVDKLLKKIILKDLQLFLVPMISLLVMVPLTVILFGPIATNVGDIISNIFMGL
                     FEFNRVIAGAAIGIAMPFLAVLGLHWGFTPITLQNLATMGGDPIEGAAVAAVFAQIGI
                     AIGLFMKVRKSKKNSELKVLAGSTAVTGILAGVTEPIIYGIILRYRRMIPVLAIAGGI
                     GGGICGVFGVTCNAYVFHNIFSMPVYTPFLGYILGIGTALVLGAVLSYFFGLSKEECE
                     EGNEEVAFDEDDGIEEILSPIEGLQIELSEVEDEVFASGTIGNGMAIIPSKGEVVSPV
                     NGTITTIFPTKHAIGITSDKGVEILIHVGLNTTMLDGKYYTTHMNAGDKVKKGDRIVS
                     FDKDKIEGEGYSIVTPIILTNTNDLADVIVKENKHIKIGTPVIKVVY"
     gene            5046..6479
                     /locus_tag="KR231_003617"
     CDS             5046..6479
                     /locus_tag="KR231_003617"
                     /EC_number="3.2.1.86"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003243232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HBH0005942.1"
                     /translation="MKSNQEFLWGGAVAAHQVEGGYNKGGKGISIADVMTAGTHTISR
                     KITDGVIEGLNYPNHEAINFYENYKEDIRLFAEMGYKCFRTSIAWTRIFPKGDESTPN
                     EDGLKFYDDLFDELLKYNIEPVITLSHFEMPYHLVKNYGGWRNRKLIDFFVNFCEVVM
                     NRYKDKVKYWMTFNEINNQSITTNPIYAFTNSGIIYEEQEDKEEVMYQAVHYEFVASA
                     KVVKIGHEINPEFKIGCMVAAMPSYPYSCNPEDMIKFVESNREQLMFTDVHVRGHYPR
                     HTLKLWERKNYNLDITEEDKKILKEGIVDFIGCSYYLTTVVTADKTMKTTGNDSAGKA
                     DVVENPYLKISDWGWNIDPVGLRFYLNQLYDKYELPIFIVENGFGAEDVLKSDNTVDD
                     DYRIEYLASHIREMKNAIEIDGVDVIGYTVWGCIDPVSFTTGEMKKRYGFIYVDKNND
                     GSGTLKRYKKKSFDWYKNVIKFNGEIL"
BASE COUNT         2592 a          639 c         1206 g         2264 t
ORIGIN      
        1 ttggaaaagt tatatattta taacataagg tgttataaat atataacttt taaggggtga
       61 ttttatatgt ctaaatcaga gcttggtgtt aaggcaaatc ttgtttcaga gttaatgatg
      121 ctatcctatt tttttataga cttgttatta caaaagttta tttttaaagg agaaggtatt
      181 tggtttactt ttataatttt attagctttt tgggtgtgca atctcatgta taataaaaaa
      241 tataatgatt tagttgatga ggcatcaaaa cttatgttgt taaaggttga tcagattgca
      301 tcaaaaataa tgttatactc tatgtttgta atagctgttc tcttttcagt taatcataca
      361 agagctttgg acatatcaaa tttggatata ggtataatgc tcttagcagt tttattcata
      421 caatctttgt caaaattaat tttgtatata tattttgata aaaagggaat atgtaactaa
      481 gtaataatat ttatgaaaac aaaaattaaa aaatatagag aatatataac ttttaaggag
      541 tgattttata tgtctaaatc agaaactggt gtaagatcaa agctcatctt ggaattactt
      601 gtaataactt atttttttat agctgtatta gctactaaat atatttttaa aggtccaagc
      661 actgcttctc ttccagggtt gagttggtta atagtttttg gatgttattc aatttataat
      721 aaaaaatata atgatttagt tgatgaatca tctgaattta tactatcaaa ggttaataag
      781 attgcaataa aaataatgat atattctata gtaataatat ctattttctt tgcaacacct
      841 tatacaagta atataaatat atcaaaccta gatacaggta taatcctcat tgcagtttta
      901 tttatacagt ctttatctaa attagtgttg tatatatact ttgataaaag ggggatatgt
      961 aactaagtgg caatattgat gaaaacaaaa attaaagaat acagagaaaa actccttatg
     1021 acgcaaaatg aacttgctaa attggttggg gtaagacgtg agactattgt acacttagaa
     1081 aatgggaaat ataatccttc tttgaagtta gctatggata tcgctaaagt attcgatact
     1141 acagtagaaa atttgtttga atttattgaa gaagaatagt ggaaagttta taaacattta
     1201 taagatggat aatgaaatat agttatttaa ttattaagtt tattaaaaat atttatataa
     1261 tatgtgatta aggttagatt ataattgttt taagataata agaagagtat tataaatgat
     1321 aaaaaatagt gaatatacag ttaattaata aacaatagat aaaaatttaa agtttaaatg
     1381 taaagaggat gtataatttt atgaaatcta ataagacact gttataatcg ctatgtaagg
     1441 aaatcatatt agaattttct aagaaaacag ttaagaattt ggaagtaagt atgtgttatt
     1501 tatatacttc tgaaacatat aaactaataa gtgaggttgt atcagatatg tcttgtaagg
     1561 gtaatttctt caggttcatc aactatcata actctacaga gggtataaga tatgctttgt
     1621 aagggtaata tatgcttgat tcaagaatta gtgttataaa atggattagc ataccaaaag
     1681 gtctattaaa gatatacagt taaaaagcta tatagtaagt taggtaaggt taataatcca
     1741 aacaatgatt tgatgattaa actgtttaga gccttagata caacagtaaa agaattattt
     1801 tttaataagg agaagtaaaa gataaaagaa aatcaaaact taggcagtta ttgtagttac
     1861 aaaataaagg atttccttat atatggataa ataatcgagt atatataata aaaaatatat
     1921 gaccttaatt ttgttatgaa ataacttcaa aacttatttt agcatgttta gattatataa
     1981 atcatataaa aaaagtagaa tgagtgaata cttatgacaa taatctagta gagatataca
     2041 tgaaattata tattgactaa gtacagttat tattttataa tgaaaataaa gttatcatac
     2101 agataaataa acggatcgtt actgagatag atgtaatcag gcgtgaccta aaaattctag
     2161 taaatgctta aagtattatt agtctttttt aggtctcttt ttgtttacag tggaggtagt
     2221 ttatggttat aaagaaagta tttaataata atgttgtatt tgccagagat aattcaggac
     2281 aagaagtaat attaatggga aaaggaattg gatttaataa atttactaaa gatttagttg
     2341 aaatagataa aattgaaaag aaatttatat tcaataatga ggaatcatta agtgaattac
     2401 attcactact agataggata cctttaaaag atgttgagct tgtaagtgaa attattcaaa
     2461 tgggaagaga agaattgggt gataatctta atgatagtat attaatcaca ttatcagaac
     2521 atataagtta tatgttaaaa agaatggatg aaggattagt atttcaaagc ccgcttcaat
     2581 gggaaataag acaaatatat cctaatgaat ataattttag taagaaagct gtagaatatt
     2641 taagaaaaaa attagataaa aatattcctg attctgaaat agcatttatt acgatacact
     2701 ttgcaaatgc tcagttagaa acaaaagata tgcaagaaac tttattgtta actaagataa
     2761 ttgataatgt attagatatc ataaagtatc actatggaat cgaaataaat gaatattcct
     2821 ttgactacac aaggtttata agtcatttaa gatgttttat aaaaaggcaa ttaagtggtg
     2881 agaatacaaa tgtagacaca tcattgttag atataataaa aatgaaatat aaaagtgatt
     2941 acaattgtgc aaaaaaagta aaaaactttc ttgaaaagac gtataaatgg aaaattagcg
     3001 aaaatgaatt gttgtactta acattgcatt taaatagatt atcaaatata aagtaaatag
     3061 tgtaggattg ttactgtttg gcaggcatga cctaagttgg tataattagt ttttaatatc
     3121 taattgtatt gatttaggtc tatttttata cataaaatta tgaaaatgga ggatagattg
     3181 tatgaaattt gaaagagagt ctgaagaaat tataaaatat gtcggaggaa aagaaaatat
     3241 tattagttta gttcattgtg caactaggct acgttttaag ctgaaagata cttcaaaaac
     3301 taacaaagaa gagttattaa aaatgaagga tgtactatct gtagtaaata gtggaggaca
     3361 ataccaagtg gtaattggaa ataaagtaac tgattacttt gaaactatta taaaaaaagc
     3421 agttttacaa ggacaaaata ctgaagaaca gggagaaaaa gtttcaatag tttctaaaat
     3481 atttgaatca atttcaggtg cattttctcc attaatacct gcactagctg gagcaggaat
     3541 gattaaggca ctgcttacaa tactaactac tatgaaatgg atgtctgata caagtagcac
     3601 ttatgctata ttatcagcag ctggaaatgc tgtattttac tttttaccaa tattcttagg
     3661 tattacctta gctataaaac ttagtgcaaa tccatatgtt ggtggagtga taggagcagc
     3721 tttgttagat cctaatttta cagctttaat tggagcaaaa ggtggtgcta acttttttgg
     3781 gatgccagta acagcaattg attattcttt tggtgtattc cctatatttg ttgctatatt
     3841 tatttattac tatgttgata agcttttaaa gaagattata ttaaaggatt tacaattatt
     3901 cttagtaccg atgatatcat tattagtcat ggttccttta actgtgattt tatttggacc
     3961 aatagcaact aatgttggtg atataatatc taatattttt atgggattat ttgaatttaa
     4021 cagagtaatt gcaggagctg caataggtat agctatgcca ttcttagcag tattaggact
     4081 acactggggc ttcacaccaa ttactttgca aaacttggct acaatgggtg gagacccaat
     4141 agaaggtgca gctgttgcag cagtatttgc tcaaataggt attgcaatag gtttatttat
     4201 gaaggttaga aaatctaaaa aaaattcaga attaaaggta ttagcaggtt caacagcagt
     4261 tacaggaatt ttagcaggag taacagaacc tataatttat ggaattatat taagatacag
     4321 aagaatgatt ccagtattgg ctattgcagg aggtattggt ggtggtatat gtggtgtatt
     4381 tggtgttact tgtaatgcat atgtatttca taatatattc tcaatgccag tttatacacc
     4441 attcctagga tatatattag gaataggaac agcattagtg ctaggagcag tattgtcata
     4501 tttctttgga ttgagtaaag aagaatgtga agaaggtaat gaagaagttg cttttgatga
     4561 agatgatggt atagaggaga tattatctcc aatagaaggc ttacaaatag agttatctga
     4621 agtagaagat gaagtgtttg catcaggaac tataggtaat ggcatggcaa taataccttc
     4681 aaagggagaa gttgtgtctc ctgtaaatgg aacaataaca actatttttc ctacaaagca
     4741 tgcaatagga attacctctg ataaaggtgt agaaatatta atacacgtag gtcttaacac
     4801 tactatgtta gatggaaagt attatactac tcatatgaat gcaggagata aagttaaaaa
     4861 aggagatagg attgtttctt tcgataagga taaaatagaa ggtgaagggt atagtattgt
     4921 tacaccaata atactaacta acacaaatga tttagcagat gtaatagtta aagaaaataa
     4981 acatattaaa attggaacgc ctgtaataaa agttgtttat taattatact ggaggagata
     5041 tttctatgaa atctaatcaa gaatttttat ggggaggggc agttgctgcc catcaagttg
     5101 aaggtggata taataaaggt ggaaaaggaa taagtattgc agatgtgatg actgcaggta
     5161 ctcatactat ttcaagaaag ataacagatg gagtaattga gggtttaaat tatcctaatc
     5221 atgaagccat taatttttat gaaaattata aagaagatat tagattattt gctgaaatgg
     5281 gatataagtg ttttaggaca agtattgctt ggactagaat ttttccaaag ggcgatgaat
     5341 caactccaaa tgaagatgga ttgaaatttt atgatgattt atttgatgaa ttattaaaat
     5401 acaatataga gccagtaata actttaagtc attttgaaat gccttatcat ttagtaaaaa
     5461 actatggtgg atggagaaat agaaaattaa tagatttctt tgtaaacttc tgtgaagtgg
     5521 taatgaatag atacaaggat aaagttaagt actggatgac tttcaatgaa ataaataatc
     5581 aaagtataac tacaaatcct atttatgcat ttactaactc gggaataatc tatgaagagc
     5641 aggaagacaa agaagaagtt atgtatcaag cagttcatta tgaatttgta gcaagtgcaa
     5701 aggttgtgaa gataggtcat gaaataaacc ctgagtttaa aattggatgt atggtggcag
     5761 ctatgccaag ttatccttat tcttgcaatc cagaggatat gattaaattt gtagaatcta
     5821 atagagaaca acttatgttt actgatgtac atgtaagagg tcattatcca agacatacac
     5881 taaaattatg ggaaagaaaa aattataatt tagatattac agaggaagat aaaaaaatcc
     5941 taaaagaagg aatagttgat tttattggat gtagttatta tttaactact gtagtaacag
     6001 ctgataaaac tatgaaaaca acaggtaatg actcggcagg aaaggctgat gtagttgaaa
     6061 atccatactt aaaaatttct gattggggat ggaatataga ccctgtaggt ctaaggtttt
     6121 accttaatca actatatgat aagtatgaac ttcctatatt cattgttgaa aatggatttg
     6181 gagcagaaga tgtattaaaa tcagataata ctgtagatga tgattataga atagagtatt
     6241 tggctagtca tataagggaa atgaaaaatg ccattgaaat tgatggtgtt gatgttatag
     6301 ggtatactgt ttggggatgt atagatccag tatcatttac aacaggagag atgaaaaaaa
     6361 gatatggatt tatatatgta gataaaaata atgatggaag tgggactctt aaaagatata
     6421 aaaagaaatc ttttgattgg tataaaaatg taataaaatt taatggagaa attttatagg
     6481 tagataaatt ttaatattta taagattatg ttaaggaaac cattaaaaat tagattaaaa
     6541 tcgtgggtat ttaaatccac taaaagatat tgactattta gtcaatatct ttttttatta
     6601 aaaagtaaat ataaagaggt aaggttaaaa attgggatat atatgattta tatagtatga
     6661 tttaattaga aggagctata ttagtattca tttgtatagt t
//
LOCUS       DAEPHU010000134         6424 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 01A10CD0081
            SAMN05941466-rid12468953.denovo.135, whole genome shotgun sequence.
ACCESSION   DAEPHU010000134 DAEPHU010000000
VERSION     DAEPHU010000134.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941466
            Sequence Read Archive: SRR6291087
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 6424)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6424)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068158.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 22:43:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,892
            CDSs (total)                      :: 3,805
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 87
            rRNAs                             :: 8, 1, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 55
            CDSs (without protein)            :: 55
            Pseudo Genes (ambiguous residues) :: 0 of 55
            Pseudo Genes (frameshifted)       :: 21 of 55
            Pseudo Genes (incomplete)         :: 28 of 55
            Pseudo Genes (internal stop)      :: 16 of 55
            Pseudo Genes (multiple problems)  :: 8 of 55
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6424
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941466-rid12468953.denovo.135"
                     /strain="01A10CD0081"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            <1..1235
                     /locus_tag="KR231_003618"
     CDS             <1..1235
                     /locus_tag="KR231_003618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HBH0005943.1"
                     /translation="IQISRLFNGGNYFSNINYLFYILAFIAWGGYYNYFYKMGYIKYS
                     IFFYLFSVYYKCLDAVIYRILFFAITGNVISSKESLLVPHLESIKIQIYSNLIIILIY
                     LIFSFFRKSIKLISQDKRNYVYLLFALLVNTMNMLVNYVLKKLERFGSLHSEGYYFDN
                     FVNPKLVGASSIFLILLFKEIIKENRLKSQAELIKNKLDMQYAHYLSIQESHMRVKKL
                     YHDINNHIYCIDNLRNNSKEINEYVNNLKDEIKTFKYIYNTGNMILDIIINEKSEICL
                     KKGIKFTCSINFSKVNFVKPIDVSSIFSNILDNAIEACDKIVDENVNKYIRIKGTMTR
                     SFFVLKCENSKLNQLTFNKNILLTNKMDKFVHGIGIQSIKSSLQKYNGELLFENSIDK
                     FILNIYIPLDQDTDSWGD"
     gene            1476..2165
                     /locus_tag="KR231_003619"
     CDS             1476..2165
                     /locus_tag="KR231_003619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0005944.1"
                     /translation="MKVKRNINRVAIIVALNLSLALMVGCMSPVYDKNLSSSEQISKD
                     SLKEQVEDKKDESIELFNNYSQKINDAKGREEVKKDLSQRFSKAIIDSGYSITDSKSD
                     GSFVVSINGAEKPPEKNIRSLFYSMSEDDKEGKVTIDILCAKEYPEDDKLSESDKYIK
                     FIYNLFKSLTNTNLTEKEIFSMVEEDFNKGVGVVELPYMKDIHVEVNKVKQSTKVLKL
                     SLVYKFDISNH"
     gene            2386..4758
                     /locus_tag="KR231_003620"
     CDS             2386..4758
                     /locus_tag="KR231_003620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate C-acetyltransferase/glycerol dehydratase
                     family glycyl radical enzyme"
                     /protein_id="HBH0005945.1"
                     /translation="MSQTNRIEAFRQEYINSKPMICCERARIFTESHKKTEGEAICIR
                     RAKAFLETCKELPIKIFENELIVGTAGKFRRTGILTPEFSWQWVDKEMDTFDKRTQDP
                     YVISKEQIEFIRKEIFPYWKGKSLEEVFLARIPEDTAKILVDTGIIDNDSKWRQAVGE
                     VTPDYQDILFVKGYKGIKEDADKKIKELDISVSENIEKIDFYKSVSIVAQGIMTLAQR
                     YSNLAKEMSKQETDEKRKLELIKISEICMNVPANPPTNFYEAIQFVWFVQLGGILSEN
                     PLALNLGRFDQYMYPYYENDAREGKITESEAQELIEALWIKLSEWVWTISANTANYFA
                     GYNQFQNLTVGGKKRNGTDGTNDISYMCLKATESVKTHQPGLSVRVSQGAPDNFVMAV
                     AKLVKQGTGFPAIHSDSAGAQMLLQDGYDAEDARDWSNCGCVVPHFRKTGQWTSAVNI
                     NFAAALEYAMNEGKSRLTGEKMGLDTKNITEFTSFEELKDEFLKQLAYLVKSSVIGTT
                     VAQQIHKEMVPRPFLSTCVDGCLDKGVDLSKGGAKYNIGPVLTGIGLGVVSNSLAAIK
                     KLVFEDKVTTLEELTKALNNDWEGYEELRKLALDVPKYGNDNDYVDSLAIEVSDFYYT
                     ETRKYKDIFGSKFNSAFMGISNYVPTGKIVGATPCGRKATKPLTEGVSPFVGTDTTSP
                     LAAMKSASKINHDVHTGGTLLNLRLNQDLVETERGLRNLTSMIKSYFALGGFHVQFNT
                     ISNDTLLKAQENPEEYKDLLVRVAGYSTQFVNLSREMQDAIIARNSHSNF"
     gene            4773..5675
                     /locus_tag="KR231_003621"
     CDS             4773..5675
                     /locus_tag="KR231_003621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycyl-radical enzyme activating protein"
                     /protein_id="HBH0005946.1"
                     /translation="MSKKGRVVKVQHFSVNDGDGIRTTIFLEGCKLKCKWCSNPDSWS
                     NIVKLGVMKDKCVSCNRCIDVCPQNISSLFDRAQINNKCDLCGECIKVCLKDAICIMT
                     EEMSVEEIVEEVEKDFIFFFESNGGITFSGGEPTLQIDFLRELVDIFYDKGINIAIET
                     CGYFDWNKVNDVFEKIDHIFVDIKSMDDNIHKEYTGVSNKIILDNICRLSKLNKSMVI
                     RVPIIYGVNDSEENIRNTALFVKQNVPGGKMELLPYHKFGIDKYKALGLEDYIYEFDD
                     ICNNHMLKLKEIVELTGVKIIEYK"
     gene            5695..6246
                     /locus_tag="KR231_003622"
     CDS             5695..6246
                     /locus_tag="KR231_003622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBH0005947.1"
                     /translation="MDNKFPNVGENLRLLRQEMGISLDKASKMTGVSKAMLGQIERGE
                     SSPTVSTLWKISSGFKINFTTLLNENTNTYEVIKKEEVEPIVEQKGNMKLYPIYPFSP
                     QRRFELFIIELEENCTHVSSTHSHVLEEYVLVIEGKLDLNVDGKTYILESGHSIRFDG
                     TLEHIYKNLNKGKTIFHNIEVYR"
BASE COUNT         2571 a          629 c         1155 g         2069 t
ORIGIN      
        1 taattcagat aagtagatta tttaatggag gaaattactt tagtaatata aactatttat
       61 tttatatatt agcatttatt gcttggggag gatactataa ttatttttat aagatgggtt
      121 atattaagta ttccattttc ttttatctat ttagtgtata ttataaatgt ttggatgctg
      181 ttatatatag aatactattt tttgcaatta caggtaatgt tatttcatct aaagaatcct
      241 tattagtacc tcacttagaa tctataaaaa ttcagatata tagtaattta ataattattc
      301 ttatatatct tatatttagc ttttttagga agtctataaa attaattagc caagataaga
      361 gaaattatgt atatttatta tttgccttat tagttaatac aatgaatatg cttgtaaatt
      421 atgtattaaa aaaattagaa cggtttgggt cattacattc agaaggatac tattttgata
      481 attttgttaa tccaaaattg gtaggagcta gtagtatatt tcttatacta ttgtttaaag
      541 aaataataaa agagaataga ttaaaatctc aagctgaatt aataaaaaat aagttagata
      601 tgcaatatgc gcattattta agtattcaag aatctcatat gcgagttaag aaactatatc
      661 acgatataaa taatcacatt tattgtatag acaaccttag aaacaatagc aaagaaatta
      721 atgaatatgt taacaattta aaagatgaaa taaaaacatt taaatatatc tataatacag
      781 gaaatatgat attagacatt ataatcaacg aaaagagtga aatatgttta aaaaaaggaa
      841 ttaaatttac ttgctctata aatttttcaa aagtaaattt tgtaaaacct atagatgtgt
      901 caagcatatt ttctaatatt ttggataatg caatagaagc atgtgataaa atagtggatg
      961 aaaatgttaa taaatatatt agaattaaag gaactatgac aaggtcattt tttgtactta
     1021 aatgtgaaaa tagtaaacta aatcagctta cttttaataa aaatatattg ttaacaaaca
     1081 aaatggataa gtttgtacat ggaataggta ttcagagtat taaatcttct ttacaaaaat
     1141 ataatggaga attattattt gaaaatagta tcgataaatt tatactaaat atatatatac
     1201 cattggacca agatactgac agttggggcg attaagttac cagttgggac atatgtattg
     1261 atacaaaaaa ataaggatgt tatcttttaa taacaaaaga taacatcctt atttctgtat
     1321 taaggagctt ataattttac taatagtaag ttataagaat tggataggaa ggtgatatgt
     1381 attgaataat aaatctttaa tataaagaaa atataaacat attctagtgc aataagtaat
     1441 actttagagc ggttagtgtg atgggaggat tgtgtatgaa agtaaaaagg aatataaata
     1501 gagtggcaat cattgtggct ttaaatctta gcttagcatt gatggtaggg tgtatgtctc
     1561 ctgtatatga taagaactta agtagctcag aacaaattag taaagattcg ttgaaagaac
     1621 aagttgaaga taaaaaagat gaatctatcg agctttttaa taattactca caaaagatta
     1681 atgatgcgaa aggtagagaa gaagtaaaaa aagatttatc tcaaagattt tcgaaagcta
     1741 taatagacag tggttatagt attactgact caaaatcaga tggtagcttt gtagtatcta
     1801 taaatggtgc tgaaaaacca cctgaaaaaa atattcgaag tttattctat tctatgtctg
     1861 aagacgataa agaaggaaaa gtaacaatag atattctctg tgctaaagag tatccagaag
     1921 atgataagtt atctgagagt gataaatata ttaaatttat atacaattta tttaagtcat
     1981 tgactaatac gaacttaact gagaaagaaa ttttttctat ggttgaagaa gactttaata
     2041 agggagtagg tgttgtagag cttccttata tgaaggatat acatgttgaa gttaacaaag
     2101 ttaaacaatc aactaaggtt ttaaaactaa gtctagtata caaatttgat atttcaaatc
     2161 attagtatat tagaaataac tataacaata tagaaaatat atcatagaaa atttttttag
     2221 agtttataaa tttaacaaaa aaagtattaa tatataggtg ttcaaggtag atgaaaaaaa
     2281 ataagttatt ttgcttccat tttatgctaa aggacagtat aatataatta aagtatgtta
     2341 taacatacaa aaatgtagta tatattatcc aaagggggat tttaaatgag tcaaactaat
     2401 agaatagaag catttagaca agaatatatt aattctaaac ctatgatatg ttgtgaaagg
     2461 gctagaattt ttacagaatc acataaaaaa actgagggag aagctatctg tataagaaga
     2521 gctaaagctt ttttggagac atgtaaagaa cttcctataa aaatctttga aaatgaatta
     2581 atagtaggta cagcaggaaa atttagaaga acagggatat tgacaccaga gttttcttgg
     2641 caatgggtag acaaagaaat ggatactttt gataaaagaa ctcaagaccc atatgtaata
     2701 tcaaaagaac aaatagaatt tataagaaaa gaaatatttc catattggaa gggaaaatct
     2761 ttggaagaag ttttcttagc aagaatccca gaagatacag ctaagatatt agtagataca
     2821 ggaataatag ataatgattc taagtggaga caggcagttg gtgaagtaac accagattat
     2881 caagatatat tgtttgtaaa aggatataaa gggattaagg aagatgcaga taaaaaaatt
     2941 aaagaattag atatatcagt ttcagaaaat attgaaaaga tagattttta caaatctgtt
     3001 tctatagttg cacagggtat tatgacattg gcacaaagat attcaaatct tgcaaaagag
     3061 atgagtaagc aagaaacaga tgaaaagaga aagttagaac ttataaaaat ttcagagata
     3121 tgtatgaatg taccagcaaa ccctccaact aatttttatg aagcaataca atttgtatgg
     3181 tttgttcaat taggtggtat tctatcagaa aatccattgg cattaaattt aggtagattt
     3241 gaccaatata tgtatccata ttatgaaaat gatgctagag aaggtaaaat aactgaatca
     3301 gaagctcaag aattgataga agcactttgg attaagttat cagaatgggt atggactata
     3361 tcagcaaata cagcaaatta ctttgcagga tataatcaat tccaaaatct tactgttggt
     3421 ggtaaaaaga gaaatggtac tgatggaacg aatgatatct catatatgtg tttaaaggct
     3481 acagaaagtg taaaaactca ccaaccagga ttaagtgtta gagtgagtca aggagcacca
     3541 gataatttcg taatggcagt tgctaaattg gtaaaacaag gaactggttt ccctgctata
     3601 cacagcgata gtgcaggggc acaaatgtta ttacaagatg gatatgatgc agaagatgct
     3661 agagattgga gtaactgtgg ttgtgtagtt cctcatttta gaaaaacagg acagtggact
     3721 tcagccgtaa atatcaattt tgcagcagct ttagaatatg ctatgaatga aggtaagagt
     3781 agattaactg gagaaaaaat ggggttagat acaaaaaata tcacagaatt tacttctttt
     3841 gaagaactta aggatgagtt tttaaagcaa ttagcatatc ttgtaaaaag ttctgttata
     3901 ggaactactg ttgctcaaca aattcataaa gaaatggtac caagaccatt tttatctact
     3961 tgtgtagatg gatgtttgga taagggagtt gatttaagta aaggaggagc aaaatataat
     4021 ataggtcctg tattaactgg tatagggtta ggtgtagttt caaattcatt ggcagctata
     4081 aaaaaattag tatttgagga taaggtgact acgttagaag aattaacaaa agcactaaat
     4141 aatgattggg aaggttatga agaattaaga aaacttgcgt tggatgttcc taagtatgga
     4201 aatgataatg attatgtaga ttcattagca attgaagttt ctgattttta ttatactgaa
     4261 actagaaaat acaaggatat ttttggctct aaatttaata gtgcatttat gggtatatca
     4321 aactatgtac caactggaaa aatagtaggt gcaactcctt gtggaagaaa agcgacaaaa
     4381 cctttgacag agggagtttc tccatttgtt ggtactgata caacaagtcc actagcagca
     4441 atgaaatctg catcaaaaat aaatcatgat gttcatactg gtggaacact tctaaattta
     4501 agactgaatc aagatttggt ggaaactgaa agaggactta gaaatctaac atctatgatt
     4561 aaatcatatt ttgctttagg aggattccat gtacaattta atacgatatc aaatgatact
     4621 ctattaaaag ctcaagaaaa tccagaagaa tataaagatt tattagtgag ggttgctgga
     4681 tatagtactc aatttgttaa tttatcaaga gaaatgcaag atgctataat agctagaaat
     4741 tcacatagca atttttaatt atgaggtaga ttatgagtaa aaaaggtaga gttgtaaaag
     4801 tacaacattt ttcagtaaat gatggagatg gaataaggac tactatattt ttagaaggat
     4861 gtaaattaaa atgtaagtgg tgttctaatc cagattcctg gagtaacata gtaaaattag
     4921 gtgttatgaa agataaatgt gtatcctgta atagatgtat agatgtttgt cctcaaaata
     4981 taagttcact atttgataga gcgcaaataa ataataaatg tgatttatgt ggagagtgta
     5041 tcaaggtatg tcttaaagat gccatttgta taatgaccga agaaatgagt gttgaagaaa
     5101 tagtagagga agttgaaaaa gattttatat ttttctttga atctaatgga gggataactt
     5161 tttctggagg tgaacctaca cttcagattg attttttaag agaattagtt gatatttttt
     5221 atgataaagg cataaatatt gcaattgaaa cttgtggata ttttgattgg aataaggtaa
     5281 atgatgtatt tgagaaaata gaccacatat ttgtagatat aaaatctatg gatgataata
     5341 ttcataaaga atatacagga gtaagtaata aaattatatt agataatata tgtaggcttt
     5401 caaagttgaa taaatctatg gttataagag tgccaattat ttatggagta aatgatagtg
     5461 aagaaaatat aagaaatact gcattatttg tcaaacaaaa tgttccagga ggcaagatgg
     5521 agttacttcc atatcataaa tttggaatcg ataaatataa ggcattaggg cttgaagatt
     5581 atatatatga atttgatgat atttgtaaca atcatatgtt aaaattaaaa gagatagtag
     5641 aacttacagg agtaaaaatc atagaataca aatagctatc aggaggattt taacatggat
     5701 aataaatttc ctaatgtggg agaaaattta aggttattga gacaagaaat gggcataagt
     5761 ttagacaaag cttcaaagat gacaggtgtc agtaaagcaa tgcttggaca gattgagaga
     5821 ggtgaatcaa gtccgacagt atctacttta tggaaaattt catctggatt taaaataaat
     5881 tttactacac tattaaatga aaatacaaat acctatgagg ttataaagaa agaagaagta
     5941 gagcctattg ttgagcaaaa agggaacatg aagttatatc caatataccc ttttagccct
     6001 caaagaaggt ttgaactttt tataattgag cttgaggaaa actgtactca tgtttcatct
     6061 acacatagtc atgttttaga agaatatgtg ctcgtaatag aaggtaaact tgaccttaat
     6121 gtggatggga aaacttatat tttagagtct ggacattcta ttaggtttga tggaacttta
     6181 gagcatatat ataaaaattt aaataaagga aaaactatat ttcacaatat agaggtttat
     6241 agataatttt atagttatcc ttttctaaaa taaatgaaaa ttttagaaaa ggataactta
     6301 tttttataat gtcgaaaaga tttatatgta tgtgatgatg ttattgtttt aaaaaaaaca
     6361 taaaagcatt ataataatat taacaaaata gaataaagag gaagagaata tgattataaa
     6421 ggtt
//
LOCUS       DAEPHU010000135         6119 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 01A10CD0081
            SAMN05941466-rid12468953.denovo.136, whole genome shotgun sequence.
ACCESSION   DAEPHU010000135 DAEPHU010000000
VERSION     DAEPHU010000135.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941466
            Sequence Read Archive: SRR6291087
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 6119)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6119)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068158.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 22:43:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,892
            CDSs (total)                      :: 3,805
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 87
            rRNAs                             :: 8, 1, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 55
            CDSs (without protein)            :: 55
            Pseudo Genes (ambiguous residues) :: 0 of 55
            Pseudo Genes (frameshifted)       :: 21 of 55
            Pseudo Genes (incomplete)         :: 28 of 55
            Pseudo Genes (internal stop)      :: 16 of 55
            Pseudo Genes (multiple problems)  :: 8 of 55
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6119
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941466-rid12468953.denovo.136"
                     /strain="01A10CD0081"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            complement(273..680)
                     /locus_tag="KR231_003623"
     CDS             complement(273..680)
                     /locus_tag="KR231_003623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0005948.1"
                     /translation="MSKVAKATFYLMIVTIISKILGMGRELVLSSIYGTGLYTESYLT
                     AMNIPNIIFAAIGTAIVTTFIPMYQDISSKQGEKQALKFLNNVLNIIVGICIVVAILG
                     VIFSKQLVSIFAIGFEGERFLLTVKFTKILIKK"
     gene            complement(1154..2038)
                     /locus_tag="KR231_003624"
     CDS             complement(1154..2038)
                     /locus_tag="KR231_003624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889336.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HBH0005949.1"
                     /translation="MDTKKENNYENYICVGSSNVSNAMKMYLKEIEEYKMLSAGEEVE
                     LAKEIINSSSVAKEKFINSNYRLVVSIAKRYKRDSIDMLDLIQAGNIGLIKAVEKYDY
                     KKGYKFSTYATWWIKQSITRYIDDCENTIRIPIHLHQRINFVKKKKQELLNVLLREPT
                     IDEIADACGLEVDKVLELLRRDKNVVSLDTPLKEDEDSSLVEFIPSDADFKDVVIHEV
                     EQHNLKEKIEELLTGLGEQEQQVLRMRFGIDDDDPKTLEQIGKVFGVTRERIRQIEAK
                     AIRKLRHPSKLKQLKHFY"
     gene            complement(2329..2805)
                     /locus_tag="KR231_003625"
     CDS             complement(2329..2805)
                     /locus_tag="KR231_003625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I restriction enzyme HsdR N-terminal
                     domain-containing protein"
                     /protein_id="HBH0005950.1"
                     /translation="MSKELVKDRVIKYLIEDLLVPQDMIDTNVELAEFEEGAEGILDI
                     VVNVKDEEDYYAPVMIVQCLDEDVELEGEVLQKQIEFLEEVDNITMSGRLVLTNGDAM
                     MYADWRGEEYDTEAALPTYDIMVKEFHEMEQQVKDLEEHHHHDENCGCGCNHHHEN"
     gene            3071..4246
                     /locus_tag="KR231_003626"
     CDS             3071..4246
                     /locus_tag="KR231_003626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1002 domain-containing protein"
                     /protein_id="HBH0005951.1"
                     /translation="MKFKKQISSIVVSTMLVLGSMNLSYADGTNVVTLGANLSESQKQ
                     QMLNYFGVKKDQVLVLDVTNAEERQYLQGVATEGQLGKVTISCSYVEPTKKGNGINVK
                     TANLTWVTSSMIASTLTTAGLEDANVIAAAPYPVSGTGALTGIMKAFEDASGKKLDET
                     KKEIASEELVVTGDLGDDIGQEKATGVMNDIKTEIVKNGTKDTNQIANTINNVVNNYN
                     ITITPEQKEQIKGVMKKIADQNYDYNSMKNTLDNVSDNVNEQLKKLGESVKGSGILDT
                     IGGWFSGIGDWFSGLFSGGDKKDLGILNNTNDESLGSDAVINSTEGVQINPQNNTNSN
                     NDSDTNSSKNDTSSNNENNDSSQTNENNTTNNSENQSNNNDSVGFFEKIKNWLSGLF"
     gene            complement(4327..5130)
                     /gene="proC"
                     /locus_tag="KR231_003627"
     CDS             complement(4327..5130)
                     /gene="proC"
                     /locus_tag="KR231_003627"
                     /EC_number="1.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrroline-5-carboxylate reductase"
                     /protein_id="HBH0005952.1"
                     /translation="MKKIGFIGAGNMASAMIGGIVNSKLVEPNMVIASAYSQGTLDRI
                     DANFGINTTKDSKEVTRTSDIVIVAVKPDIYDDILEEIKDFIDDNKIIVTIAAGKSIK
                     DIESIIGEDKKIVRTMPNTPALVNEAMSSLSINKNINKEDLEAVTEVFNSFGNTEVVP
                     EYLIEAVIGASGSAPAYVFLFIEAIADAAVIAGMPRPQAYKFASQAVMGSAKMVLETG
                     KHPGELKDMVCSPGGTTIEAVKVLEEEGFRASVIKAICACIEKSKKMSE"
     gene            complement(5170..5754)
                     /locus_tag="KR231_003628"
     CDS             complement(5170..5754)
                     /locus_tag="KR231_003628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBH0005953.1"
                     /translation="MNKDIGAKIKQLRTQKQMTLKDMSEKTNLSIGFLSQLERGLTSV
                     ATDSLGKIASVLDVELTYFFMKPKEHKRAVLRSYEKEVFDVENSTFIHYHLSSSLKEK
                     TMLPRLIEILPSKSSEEICCYVHEGEEFVYVLEGTLTVFLGDEQIEMYPGDTIHYNSE
                     KNNHNWVNYTNKVVKILVVSIPNPFEKSDAVKEA"
BASE COUNT         2024 a         1044 c          689 g         2362 t
ORIGIN      
        1 cgttgaagtt tctcctgttc ggagtttacc tgctgattgc ccattttaaa gtacttagga
       61 tttaacctta taccatctaa ccaatttttt ctactttcgt aactttcaca cttaggttta
      121 tttcatcctt atgttttagt ttgattagct ttaggggttt ccagcaattc aagtagtatt
      181 ggataggttc tatcctatct ctacatatag gtttccctat atgctgacta ttttagctac
      241 taactcatga ctaaagtcac gagtgtgtgt agctattttt taatcaatat tttagtaaat
      301 tttacggtaa gtaaaaacct ctctccttca aatcctatag caaatatact tacaagttgc
      361 tttgagaaaa taactcctaa tatagctaca actatgcata taccaactat tatatttaaa
      421 acattgttta aaaactttag tgcttgcttt tcaccttgtt tactacttat atcttgatac
      481 attggaataa aagtagtaac tatagcagta cctattgctg caaatataat atttggtata
      541 ttcatagctg ttaaataact ctctgtatat aagcctgtac cataaattga tgataatact
      601 aattctctac ccattccaag aatcttagag attatagtaa ctatcatcaa ataaaaagtt
      661 gctttagcta ccttgctcat tttatcactc cacttctaac atacctcttt ttaatcaagt
      721 aaaatttagc tcattagata taattctatc aactaatttg ccttgcttag ccctatcaaa
      781 atataattaa cacctatttc ttaatatatc acaaactaca ttattcttca tattttttta
      841 tttctccaat aagttttaca tttttcctat ataaattgta tagcttcaat tatattcaaa
      901 gaaatggagt tgctacccga taactttaaa agtaaaaaac agattttatt atctttttaa
      961 actatattct aacatatttt gtccatattg agaaatttta ctaaactatt atgtacttta
     1021 ttaaataaat aaaataacag cacacctata aaatacaagt gtgctgttca taaacagatt
     1081 ttataaaaaa ataattccta agtagagatt aacatgcttt ctcatactct catatataat
     1141 gtgtctaaaa atattaataa aaatgtttta attgttttaa cttacttgga tgtcttaatt
     1201 ttcttattgc tttagcttct atctgtctta ttcgttctct ggtaactcca aatacctttc
     1261 caatctgttc tagtgtttta gggtcatcat catcaattcc aaatctcatt cttaaaactt
     1321 gctgttcttg ctctccaaga cctgtaagta gttcttctat cttttctttt aaattatgct
     1381 gttcaacttc gtgtattaca acatctttaa aatcagcatc tgatggtata aattcaacta
     1441 aactactatc ctcatcttct tttaatggag tatccaaaga tacaacattt ttatctcttc
     1501 ttaataattc caacactttg tcaacttcta agccacatgc atctgcaatc tcatctatag
     1561 ttggctctct taataataca tttaaaagtt cttgtttctt tttctttaca aaatttattc
     1621 tctgatgaag atgtataggt atcctaatag tattttcgca atcgtcgata tatcttgtta
     1681 tactttgttt tatccaccaa gttgcataag tgctaaattt gtatcctttt ttataatcgt
     1741 acttttctac agcttttata agtcctatat ttcctgcttg aattaaatcc aacatatcaa
     1801 tactatctct tttatatctc tttgctatgc tcactaccaa cctataattt gaatttataa
     1861 atttttcttt tgctactgaa gatgagttga ttatttcctt agccagctct acctcttctc
     1921 ctgctgacaa cattttgtat tcctctattt cctttaaata cattttcatc gcattcgata
     1981 catttgatga acccacacaa atataatttt cataattatt ttctttttta gtatccataa
     2041 tcaaacccct tctattcata gaatttgcta aaacaaaaat aaataattta aacctacata
     2101 atctacaatt acataatatc ccattcttta aatgaattgt tttgtatatt atgtatacaa
     2161 atttataaaa actataccta taatattatt ctacttctaa cagcaatatc ctccttatat
     2221 atataattta ttttattata tgttgttata ttcttagttt tttgaatgat atatgtctaa
     2281 aaaaagactg tttactaaac agtctttttt tatatatatg ctcaatattt aattttcatg
     2341 atgatgatta catccacatc cacaattttc atcatggtga tgatgttctt ctaaatcttt
     2401 tacctgttgt tccatttcat gaaactcttt taccattata tcataagttg gaagagctgc
     2461 ctcagtatcg tattcttccc ctctccaatc agcgtacatc atagcatctc cattagttaa
     2521 aaccaatcta cctgacatag ttatattatc cacttcttct aaaaattcta tttgtttttg
     2581 taaaacttct ccttctaact ccacatcttc atctaaacat tgcactatca ttacaggtgc
     2641 ataataatct tcttcatctt taacatttac aacaatatct aaaattcctt ctgcaccttc
     2701 ttcaaattct gccaactcaa catttgtatc aatcatatct tgaggtacta ataaatcttc
     2761 tattaaatat tttattactc tatcttttac taattctttt gacatttatt tttctccttc
     2821 cgattctata acattatcat aatcatttct atattatagt atactacatt aattgttttt
     2881 tcaatctctt acaaaaatta ttttttatta tcttccttat attccctttt ttattacaaa
     2941 gttgtaatcg cattgattta aaaaatagtt tatatttagt ataatagaaa tgtagcacat
     3001 atttttattc aatatattaa taaaaaaata tattgaaaat gtaatgtatg ttaaatctag
     3061 gaggaatatt atgaagttta aaaaacaaat tagttctatt gttgtgtcta ctatgcttgt
     3121 acttgggagt atgaaccttt cttatgcaga cggtacaaat gtagttacac ttggagctaa
     3181 cttatcagag tctcaaaagc agcaaatgct taattacttt ggagtaaaaa aagaccaagt
     3241 cttagtttta gatgtaacaa atgcagaaga aagacagtat ttacaaggtg ttgcaacaga
     3301 gggtcaactt ggaaaagtta ctatctcttg ctcatacgtt gaacctacta aaaaaggaaa
     3361 tggaattaat gttaaaacag caaacttaac ttgggtaact agttcaatga ttgcttcaac
     3421 ccttacaaca gctggtcttg aagatgcaaa tgttattgct gctgctccat atcctgtaag
     3481 tggtactgga gcattgacag gaatcatgaa agcatttgag gatgcttcag gaaagaaact
     3541 tgatgaaact aagaaagaaa ttgcttctga agaattggta gttacaggtg acttaggaga
     3601 tgatataggg caagaaaaag caacaggtgt aatgaatgat ataaaaacag aaattgtaaa
     3661 aaatggtaca aaagatacca atcaaatagc aaatacaata aataatgttg taaataatta
     3721 caatattact attacaccag aacaaaaaga acaaattaaa ggtgtaatga aaaaaatagc
     3781 tgaccaaaat tacgattaca atagcatgaa aaatacacta gataatgtat cagataatgt
     3841 aaatgaacaa ttaaagaaat taggtgaaag tgttaagggt tctggtatac tagatactat
     3901 tggtggatgg tttagtggaa taggagactg gttctctggt ttattctcag gcggagataa
     3961 aaaagatttg ggaatcttaa ataatactaa tgatgagtct cttggctctg atgctgtaat
     4021 aaattctaca gaaggtgttc aaataaatcc acaaaataat actaattcta acaatgatag
     4081 tgatacaaat agctcaaaaa atgatacttc aagtaataat gaaaataacg atagttctca
     4141 aacaaatgaa aacaacacaa caaataattc agaaaatcaa tcaaataata atgactcagt
     4201 tggtttcttt gaaaaaataa aaaattggct ttcaggctta ttttagaaat taaacaaata
     4261 aaaagaattg cctaaaatgg aaattttcta taaaaggcaa ttctctttat ttacaataaa
     4321 tttttattac tcactcattt ttttagattt ttctatacat gcacatattg cttttatcac
     4381 agaagctcta aaaccttctt cttcaagtac tttaactgct tctatagtag ttccaccagg
     4441 tgaacatacc atatctttta attcaccagg atgttttcct gtctcaagta ccatttttgc
     4501 agaacccata acagcctgtg atgcaaactt atatgcttgt ggtcttggca ttcctgcaat
     4561 tactgctgca tctgctatag cttctataaa taaaaataca tatgctggtg cagaaccact
     4621 tgcaccaatt acagcttcta taagatactc tggtactacc tcagtatttc caaaagaatt
     4681 aaatacttct gtaactgctt ctaagtcttc tttgtttata tttttattta tagaaagaga
     4741 agacatggct tcatttacaa gagctggagt atttggcata gttctaacta tttttttatc
     4801 ttctcctata atagactcta tatcttttat agattttcct gctgctattg taactataat
     4861 tttattgtca tctataaagt cttttatctc ttccaaaata tcatcatata tatctggttt
     4921 aacagctaca attactatat cagaggttct agttacttcc ttcgagtctt ttgtagtatt
     4981 tattccaaaa tttgcatcta ttctatcaag agttccttga ctatatgctg atgctataac
     5041 catattaggt tcaactaatt ttgaatttac tattccccct atcatagcgc ttgccatatt
     5101 tcctgcacct atgaatccaa tttttttcac tttagtacct ccttattgac taatagtaat
     5161 cgttaaaatt taagcttctt taactgcatc agacttttca aatggatttg gtatacttac
     5221 taccaaaatt ttcactacct tattagtata gttgacccaa ttatgattgt tcttttcact
     5281 attatagtgt attgtgtctc ctggatacat ttctatttgt tcatctccca aaaacactgt
     5341 aagagtaccc tctaatacat acacaaattc ctcaccttca tgtacgtaac aacaaatttc
     5401 ctcactactc ttacttggaa gaatttcaat taatcttggt agcattgttt tttcctttaa
     5461 actagatgat aaatgataat gtataaatgt tgagttttct acatcaaata cttctttttc
     5521 ataacttctt aatacagctc ttttatgctc ttttggcttc ataaaaaagt aagttaattc
     5581 tacatctagt acacttgcta tttttcctaa ggaatctgtt gccacacttg ttaatcctct
     5641 ttcaagttgt gataaaaaac caattgacaa gtttgttttt tcactcatat ccttcagcgt
     5701 catttgcttt tgagttctga gttgctttat ttttgctcct atgtccttat tcaaaaccat
     5761 cacccctaaa taattttaat tttttcataa tataaataca aaaatataaa tataggtact
     5821 gaacctatct ttatttcatt taaaaaaatt tttataagta ttactataat ttatcaatct
     5881 ttttttgtct acatttttac gattatttac gatttatttt tcacatatgt atatttaatc
     5941 ttgccaacta aagatacatt ttttataagc atttactctt tatataataa aacttaagtt
     6001 gttcatgagt cttcttctgg tttaattatt aaaatttcaa attatattat tatttctaca
     6061 cattattaca tcctttagta caattataac ataattttac aatttaatga tatctattc
//
LOCUS       DAEPHU010000136         6111 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 01A10CD0081
            SAMN05941466-rid12468953.denovo.137, whole genome shotgun sequence.
ACCESSION   DAEPHU010000136 DAEPHU010000000
VERSION     DAEPHU010000136.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941466
            Sequence Read Archive: SRR6291087
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 6111)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6111)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068158.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 22:43:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,892
            CDSs (total)                      :: 3,805
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 87
            rRNAs                             :: 8, 1, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 55
            CDSs (without protein)            :: 55
            Pseudo Genes (ambiguous residues) :: 0 of 55
            Pseudo Genes (frameshifted)       :: 21 of 55
            Pseudo Genes (incomplete)         :: 28 of 55
            Pseudo Genes (internal stop)      :: 16 of 55
            Pseudo Genes (multiple problems)  :: 8 of 55
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6111
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941466-rid12468953.denovo.137"
                     /strain="01A10CD0081"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            90..911
                     /locus_tag="KR231_003629"
     CDS             90..911
                     /locus_tag="KR231_003629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidinol-phosphatase HisJ family protein"
                     /protein_id="HBH0005954.1"
                     /translation="MNLIDNHIHTNFSSDGKDSMEDTIKKAISIGVRYLTFTDHLEHD
                     EDRGFCINYNDYVPVFNKFKEKYKKDIELLLGVEVGYRKHLKNEIEEIINSNPFDFVL
                     CSTHTIDNVPVPSKEYFKGLSKEDAYYKYFNSILETNREFGDYNIYGHLDYISRYGIY
                     SDNRVIYNDFKDVIDEVLKSIINNGSGIELNTSGYRYGLNAIHPNEDILKRYKELGGF
                     IVTVGSDSHRVEDICKDFDVAYDMLKYLDFKYVSLFKERETYFVNIEKVKSNNIA"
     gene            1169..3052
                     /locus_tag="KR231_003630"
     CDS             1169..3052
                     /locus_tag="KR231_003630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glycosidase"
                     /protein_id="HBH0005955.1"
                     /translation="MSNKNKENITLSNQIKGTIQNSLTKEAILHIPMSNYAYGYDRET
                     LHIRLRTKKNEAKRVILRIGDQYVWDKGGAGGGNLNASGVGWSGGTNIVMSKEVETEL
                     FDYWIAKCKPLNKRSRYGFIIEGQEEKLLFTEKRIIELGNENDEKELCEIGNFFGYPY
                     LNYIDIPKVPNWVKDTVWYQIFPDRFANGDPSINPEGVDKWGAIPTRDNFTGGDLQGV
                     IEHLDYLSDLGINGIYFCPITIGKTNHRYDTVDYMEVDPTLGDKETLKKLIEEAHKRN
                     IKIMLDAVFNHIGYYSKQWQDVVQNKENSRYKNWFYIKDMSKIDTPIEQIDEKNIPYE
                     TFGCEKYMPKLNTENSEVIKYLLDVGKYWIQEFDIDAWRLDVSNEVDHVFWRKFREEV
                     KKVKPDIYILGEIWHGSLPWLMGDQFDSVMNYLMSEAMKKFFCTDEINAEEFKYMIND
                     VMVSYPIQVSEVIFNLLGSHDTTRILTYANGNIDRFKLAYMFMFVQTGCPCIYYGDEI
                     GMEGELSSISEGQRKCMEWNEEKWNKDIFDFMKKIIRLRKENKELRSISNEWVLADKE
                     NGTIILKKESISIIINNSSKNIILTLPDYLANKKVKDLYEEEIVDLKEELMLEKYKFI
                     ILK"
     gene            3277..3957
                     /gene="pgmB"
                     /locus_tag="KR231_003631"
     CDS             3277..3957
                     /gene="pgmB"
                     /locus_tag="KR231_003631"
                     /EC_number="5.4.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-phosphoglucomutase"
                     /protein_id="HBH0005956.1"
                     /translation="MIEAFIFDLDGVITDTAYYHYMAWRKLAHKVGIDIDTKFNESLK
                     GISRMESLDRILEFGNKKYSFSEEEKVRMAEEKNNYYVSLIDEITSNDILPGIESLLI
                     DVKSNNIKIGLSSASKNAINVLNHLGISDKFDFIADAGKCKNNKPHPEIFLMSAKGLN
                     VNPQNCIGIEDASAGIDAINSANMFSVGVGNYENLKKANLVVDSTNQLKFEYIQEKYN
                     EYIVRRII"
     gene            3954..>6111
                     /locus_tag="KR231_003632"
     CDS             3954..>6111
                     /locus_tag="KR231_003632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 65 protein"
                     /protein_id="HBH0005957.1"
                     /translation="MKCLFSNVDEWKIIQDKIEIKENRLAESIMSIGNGYMGMRGNYE
                     ENYSGDTHKGSYIAGVWFPDKTRVGWWKNGYPEYFGKIPNSVNYIGVRIFIDDVELDL
                     AKCKVEDFYRELDMKNGILNRRFIVNINDKKFEVRVARFLSISVKELAVIKYSIKSLN
                     SNTKIKFVPYLDSNIKNEDSNYEEKFWNGISSSSLEYKGSILSRTKENAFNTPVFTVG
                     SMMYIKTNGDVEAVSHESDYNYCENSITMDVLKNEVASIEKYVSITSTRDYKESELLR
                     KCEDILNRELSKSYDDILNEHTKLWNKRWESADVKINGDKSSQQGIRYNLFQLFSTYY
                     GEDSRLNIGPKGFTGEKYGGATYWDTEAFCVPVYLGVADKEVTRNLLEYRYNQLEQAK
                     DNAKKLGLKGALYPMVTFDGVECHNEWEITFEEIHRNGSIVYAIYNYTNYTGDYKYIK
                     EKGIDVIIEIARFWASRVHLSTKKDLYMIHGVTGPNEYENNINNNWYTNYIAKWCLDY
                     AVENILRLEKECNECIDRNNVTREEVEFWKIISNKMYLPYDEELQIIIQNDNFLDKEF
                     VEVKDLPKENFPLNQNWSWDKILRSCFIKQADVLQGIYYFGNRFTKEEKKRNFDFYEK
                     YTVHESSLSSSIYSIIASEIDNLEKAYELYSRTARLDLDNYNNDTNDGLHITSMSGSW
                     LSIVHGFAGMRTWNETLSFDPKLPKEWKNYSFNINYR"
BASE COUNT         2501 a          544 c         1128 g         1938 t
ORIGIN      
        1 aaaatttaac cattataatt ttcttttaac aaatgtatac aataaacttg ttgtataatt
       61 aagatagata aaataaaggg agggataata tgaatttaat agataatcat attcatacta
      121 atttttcaag tgatggaaag gattccatgg aagatacaat aaaaaaagct ataagtattg
      181 gtgttagata tttgactttt acagaccatt tagaacatga tgaagataga ggattttgca
      241 taaattataa tgactatgtt ccagtattta ataagtttaa agaaaaatat aaaaaggaca
      301 tagagttatt actaggtgtt gaagtgggtt acagaaaaca tctaaaaaat gaaatagaag
      361 aaataataaa ttctaatcct tttgattttg tattgtgctc aactcataca attgacaatg
      421 tacctgttcc atcaaaggag tattttaaag gtcttagcaa agaagatgcg tattataaat
      481 attttaatag catacttgaa actaatcgtg aatttggaga ttacaatata tatggtcatt
      541 tggattatat atctaggtat ggaatatatt cagataatag agttatatac aatgacttta
      601 aagatgttat tgatgaggtc ttaaagtcaa taatcaataa tgggagtggt atagagctaa
      661 atacttctgg ttatagatat ggattaaatg ctatacatcc aaatgaagat attctaaaaa
      721 gatataaaga acttggagga tttatagtta ctgtaggttc tgattctcat agggtagaag
      781 atatatgtaa agattttgat gtggcctatg atatgcttaa gtatcttgac tttaaatatg
      841 tatctttatt taaagaaaga gaaacttatt ttgtaaatat agaaaaagtt aaatctaaca
      901 atatagctta gagtgtgttt tgaagtaaat taatggatag ttaaaaagtt aatagttata
      961 atattgtatc ctctagaaaa atactagagg tttttatttt gctaaaataa ctaaatagaa
     1021 ttaaatttaa atagtatagt ttattttaaa ttgaatagtt tattgttgat atattttact
     1081 attatatatt tttattgtga tataatagta aaatatatta acctatcttt agattatata
     1141 aattattata aaggagggaa attttaaaat gtctaataaa aataaagaaa atataacttt
     1201 aagtaatcaa atcaaaggaa caattcaaaa tagtttaaca aaagaagcta tattacatat
     1261 accaatgagc aattatgcct atggttatga tagagaaaca ctacatataa gacttagaac
     1321 taaaaaaaat gaagcgaaaa gagtaatttt acgaatagga gaccaatatg tgtgggataa
     1381 aggaggtgca ggaggaggaa atttaaatgc atctggagtt ggttggtctg gtggaacaaa
     1441 tatagtaatg agtaaagaag tagaaactga attatttgac tattggatag ctaagtgtaa
     1501 gcctttaaat aaacgctcac gatatggctt tataatagaa ggtcaagagg aaaaactttt
     1561 atttacagaa aaaagaataa tagagttggg aaatgaaaat gatgaaaagg aattatgtga
     1621 aataggtaat ttttttggat atccatattt aaattatata gatataccta aagtgccaaa
     1681 ttgggtgaaa gatactgttt ggtatcagat atttccagat agatttgcaa atggtgaccc
     1741 gtctataaac ccagaaggag tagataaatg gggagctatt ccaaccagag ataattttac
     1801 aggtggagat ttacaaggtg tgatagaaca cttagattat ttgagtgatt tgggaataaa
     1861 cggaatttac ttttgcccta ttacaattgg aaaaaccaat catagatatg atacggtaga
     1921 ttatatggag gtagacccta cattaggaga taaagagact ttaaaaaaac taatagaaga
     1981 agcgcataag agaaatataa aaataatgtt ggatgctgtt tttaatcata taggatatta
     2041 ttctaaacag tggcaagatg tagttcaaaa taaggaaaat tctcgatata aaaactggtt
     2101 ttatataaaa gatatgagta aaattgatac tccaatagaa caaatagatg aaaaaaatat
     2161 accttatgaa acctttgggt gtgaaaaata tatgcctaaa cttaatacag aaaattcaga
     2221 agtaataaaa tatttattgg atgtaggcaa gtactggata caggaatttg atatagatgc
     2281 gtggagatta gatgtttcaa atgaagtaga ccatgttttt tggagaaagt ttagagaaga
     2341 agtcaaaaaa gtaaaaccag acatttatat attgggagaa atttggcatg gtagtttacc
     2401 atggctaatg ggtgaccaat ttgattcagt tatgaattac ttgatgtcag aagccatgaa
     2461 aaaattcttt tgtacagatg agataaacgc cgaagaattt aagtatatga taaatgatgt
     2521 aatggtaagt tatccaatac aagttagtga agttattttt aatttacttg gaagtcacga
     2581 tactacaaga atattgactt atgctaatgg aaatattgat agatttaaac ttgcatatat
     2641 gtttatgttt gtacaaacag gatgtccttg tatatactat ggtgatgaaa tcggaatgga
     2701 aggagaatta agttcaatat ctgaaggtca aagaaaatgt atggaatgga atgaagaaaa
     2761 atggaataag gatatatttg attttatgaa gaagattatt agacttcgta aagaaaataa
     2821 agaacttagg tctatatcaa atgaatgggt gttagcagat aaggaaaatg gaacgattat
     2881 attgaaaaaa gaatctattt ctataataat aaataattca tctaaaaata taattttgac
     2941 gttaccagat tatttagcaa ataaaaaagt aaaagattta tatgaagaag aaatagttga
     3001 tttaaaagaa gaactaatgt tagagaaata caagttcatt attttaaaat aatacaaaaa
     3061 agtatttatt ttagatttca tgttaaatta ttatacagtt taaataagtc tttataaacg
     3121 ataaaaaaat atggtctaca agtgagtgaa ttgaaagtag attttaaatt aaagactgag
     3181 ttagagtaga taattttata aataatatct taaatacaag atagaaaata aattgattat
     3241 tagtctaaaa atttcttgta gaaagaggaa ataagaatga ttgaagcatt tatatttgat
     3301 ttagatggtg taattacaga tactgcatat tatcactata tggcttggag aaaactagcc
     3361 cataaagttg ggatagatat agacacaaaa tttaatgaat ctttaaaagg cataagtaga
     3421 atggagtcat tggacaggat attagaattt ggaaataaga aatattcatt ttcagaagaa
     3481 gaaaaagtga gaatggctga agaaaaaaat aattactatg tatcattgat agatgagata
     3541 acttcaaatg atattttgcc aggtatagaa agcttgttaa ttgatgtaaa atctaataat
     3601 ataaagatag gtctatcttc tgcaagtaag aatgcaataa atgtattaaa tcatttgggt
     3661 ataagtgaca aatttgattt tatagctgat gcaggaaaat gtaaaaacaa taaaccacat
     3721 ccagagatat ttcttatgtc agcgaaaggg cttaatgtaa atccacaaaa ttgtataggg
     3781 atagaggatg caagtgcagg tatagacgct ataaactcag ctaatatgtt ttctgttggt
     3841 gttggaaatt atgaaaactt aaaaaaagca aatttagttg tagattcaac aaatcaatta
     3901 aagtttgaat atatacaaga aaagtataat gagtatatag ttaggagaat tatatgaaat
     3961 gtttatttag taatgtagat gagtggaaga ttatacaaga taagattgaa atcaaagaaa
     4021 atagattagc agagtccata atgagtatag gcaatggata tatgggtatg agaggaaact
     4081 atgaggaaaa ttatagtgga gatacacaca aggggtctta tatagctgga gtatggtttc
     4141 cagataaaac tcgtgttggt tggtggaaaa atgggtatcc agaatacttt ggtaaaattc
     4201 ctaattcagt caactatata ggtgtaagaa ttttcataga tgatgtagaa ttagatttag
     4261 caaaatgtaa agtagaagat ttttatagag aattagatat gaaaaatggt attttaaatc
     4321 gtaggtttat tgtaaatata aatgataaaa aatttgaagt tagggttgct aggtttttaa
     4381 gtatatctgt taaggaactt gcagtaatta aatacagtat aaaatcatta aattctaata
     4441 ctaaaataaa atttgtacca tatttagatt caaatataaa aaatgaagat tcaaactatg
     4501 aggaaaagtt ttggaatgga atttcttcaa gttctttaga atataaaggt agtattcttt
     4561 ctcgaacaaa ggagaatgca tttaatacac cagtattcac tgtgggttca atgatgtata
     4621 ttaagacaaa tggtgatgta gaagctgtat ctcatgagag tgattataat tactgtgaaa
     4681 attcgataac aatggatgtt ttaaaaaatg aggttgcaag tatagaaaaa tatgtatcta
     4741 taacttcaac tagagattat aaggaaagtg agctattaag aaaatgtgaa gacattttaa
     4801 atagagaact atctaaaagt tatgatgata tattaaatga acatacaaag ttatggaata
     4861 aaagatggga aagtgcagat gtaaaaataa atggagataa aagtagccaa caaggtataa
     4921 gatataattt attccaacta ttttcaacat attatggaga agattcgcga ttaaatatag
     4981 gtccaaaagg atttactggt gaaaagtatg gaggagctac ttattgggat acagaagcgt
     5041 tttgtgttcc agtatatcta ggtgtagcag ataaggaggt aactagaaat cttttagaat
     5101 ataggtacaa tcagttagaa caggcaaagg ataatgcaaa aaaactaggg cttaaaggtg
     5161 ctttatatcc aatggtaaca tttgatggag tagaatgtca taatgaatgg gagataacat
     5221 ttgaggaaat ccaccgaaat ggaagtatag tatatgcaat atataactat acaaattata
     5281 caggtgacta taaatatata aaagaaaaag gaatagatgt aataatagaa atagctagat
     5341 tttgggcaag tagagttcat ttgtctacaa aaaaagattt gtatatgata catggagtaa
     5401 caggtccaaa cgagtatgaa aacaatatca ataataattg gtatactaat tatatagcta
     5461 aatggtgttt agattatgct gtagaaaata tcttacgatt agagaaagag tgtaatgaat
     5521 gtattgacag aaataatgtg actagggaag aagttgagtt ttggaaaata atatcaaata
     5581 aaatgtatct gccgtatgat gaggaactac aaataataat tcaaaatgat aattttttag
     5641 ataaagaatt tgtagaagta aaggatttac caaaagaaaa ttttcctctt aatcaaaatt
     5701 ggtcttggga taagattctt aggtcgtgtt ttataaaaca agcagatgta ttacagggaa
     5761 tttactattt tggaaataga tttactaaag aagaaaaaaa gagaaatttt gacttctatg
     5821 aaaaatatac tgtacatgaa tcttctttat cttctagtat ttattctatt attgcctcag
     5881 aaatagataa cctagaaaag gcttatgaat tatattcaag aacagctagg cttgatttag
     5941 ataattacaa taatgataca aatgatggac tgcacataac ttcaatgtct ggttcatggc
     6001 tttccattgt acatggattt gcaggcatga gaacatggaa tgaaactcta tcttttgacc
     6061 ctaagttgcc aaaagagtgg aaaaattatt ctttcaatat aaattataga g
//
LOCUS       DAEPHU010000137         5941 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 01A10CD0081
            SAMN05941466-rid12468953.denovo.138, whole genome shotgun sequence.
ACCESSION   DAEPHU010000137 DAEPHU010000000
VERSION     DAEPHU010000137.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941466
            Sequence Read Archive: SRR6291087
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 5941)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5941)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068158.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 22:43:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,892
            CDSs (total)                      :: 3,805
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 87
            rRNAs                             :: 8, 1, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 55
            CDSs (without protein)            :: 55
            Pseudo Genes (ambiguous residues) :: 0 of 55
            Pseudo Genes (frameshifted)       :: 21 of 55
            Pseudo Genes (incomplete)         :: 28 of 55
            Pseudo Genes (internal stop)      :: 16 of 55
            Pseudo Genes (multiple problems)  :: 8 of 55
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5941
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941466-rid12468953.denovo.138"
                     /strain="01A10CD0081"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            506..1834
                     /locus_tag="KR231_003633"
     CDS             506..1834
                     /locus_tag="KR231_003633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HBH0005958.1"
                     /translation="MGSNELKKTLGVSAALSTVVGSVIGAGVFFKPQAVYTLTGGAPG
                     LGILAWLIAGIITITAGLTAAEVSVAIPKTGGMMVYIKEIYGEKLGFLTGWMQIVLFY
                     PGMMAALGVIFGEQASALIGSPSLLLPIAIGIIVIVAGLNMLGSKTGGVIQTVSTICK
                     LIPLILIMVVGFIKGGGNNPILTPMVGEGLSLGSVLGQVLIAILFAFDGWMNVGTLAG
                     EMKNPGKDLPKAIIGGLSVVMAVYFIINLAYLWVLPANELANYASPASAVAEVIFGSM
                     GGKIISVGILISVFGALNGFLLTGSRVAYTLATDKTLPKYGIFSKLNSAQVPANAIAL
                     VSVIASIYALSGQFNLLTDLAVFATWIFYVLTFIGVMKLRKTHPNIPREYKVPLYPIV
                     PIIAIASGIFVVVNQLCFAGMKTTMISIGGLVITAIGLPVYAYMTRGVKR"
     gene            2587..3420
                     /locus_tag="KR231_003634"
     CDS             2587..3420
                     /locus_tag="KR231_003634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase"
                     /protein_id="HBH0005959.1"
                     /translation="MRNKKKKINRKKLYLLLSAIVVCLAFIVVGVRVSSLNMKENEIS
                     RNAKLSSSTITDIVSNTSIEVSKGPSKSSGKIAYITIDDGPSKFTDEMIKTLNKYNVK
                     ATFFMIDGNMKEYPQQVKNIIKNGNTAGFHSVSHDIHKLYVTSTSAKEEFDTNDQTFY
                     KITGKHSKVIRIPYGSKPYTPQASYQALVDAGYKIWDWDLDTEDWRSNSSQIVQNVKN
                     HIKNRKGEDKDQLVVLMHEKKQSAEALDSVLKFLSDEGYEFAPVDQNQIPKNYWLRNL
                     E"
     gene            3513..4445
                     /locus_tag="KR231_003635"
     CDS             3513..4445
                     /locus_tag="KR231_003635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HBH0005960.1"
                     /translation="MVGILSLMMVGCNKSLAKVNDVEITKEQYKKTKAVLSATNNYIN
                     GQSLDELEKTLDKKGRNKLENVIISFMVDNELLYQEAKDKGLTPSKSEVDSKYQELED
                     KMNLNTSYKEKMDKAGVDKDYLKQEISRDLAIDKNKKAFEDRINISDNDMEAYYTSHK
                     KDFNVEEVSASQILISTLDKNKKEVSKDKKEALKKKADNILTKIKNGESFESLAKKYS
                     DDKATGKNGGQLGYFTKDDKNAEFTKEVFKLKKNEVSNVFETSYGYHIVKVTDKRERQ
                     KSFNECQSLIRESILNEKYIEHIKKLNEDAKIDR"
     gene            4497..4979
                     /locus_tag="KR231_003636"
     CDS             4497..4979
                     /locus_tag="KR231_003636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HBH0005961.1"
                     /translation="MFKSLKRTKVEKYIIDNKDSFYRIAYSYTKNEEDALDVVQEAMY
                     KALYSVENIKEVNYIKTWFYKILVRTSIDFIRKNRKYNNMTDIDLIDETGEYDKYTDL
                     DLRRALEELPIEYKSIIILRFFEDLKIEEVAIILDENVNTVKTRLYTALKKLKLKIEE
                     "
     gene            4991..5860
                     /locus_tag="KR231_003637"
     CDS             4991..5860
                     /locus_tag="KR231_003637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3298 domain-containing protein"
                     /protein_id="HBH0005962.1"
                     /translation="MTSKERLNKLKDEYHKIPIPKKLDTIINHEKIENIYREKNKKVN
                     RLRFKVAIAFACIFTVLVNISPVFADNFSKIPVIGAIVEVITIKNYSLKSENYEAEID
                     IPKIRGLKDKNLEQRLNSSFMEDGKRLYHQFQERMEKIQSSKNKGYKSLSLSYSVKNN
                     SKKFLSIEMTKNEIEASSYVSKVHYTIDKKRQIVLTLPMLFKDDKYIKVISDNIKEQM
                     REQMKKDSTKSYFIDQKKDLPVEDFKTINKYQDFYFNKNEDLVICFDEYEVAPGYMGA
                     VEFVIPYKVIKDL"
BASE COUNT         2454 a          570 c          996 g         1921 t
ORIGIN      
        1 caaagctaat atttcatttt taaataaaaa aataaaatat tagttttgat ttctggttta
       61 aattgggtta taataaattg tcaaattatt tattaatata aaatagacta taaaacaagc
      121 aaaaatcata ctattatata aaagacctta aagatagaaa actacagaaa gaagccaaaa
      181 tgtttttgaa aaaaatgaaa ttttattgca aaaaaatcaa aatgaattta acttaatagt
      241 tataatctat ttttagtgtt acaaatatac aatgtatatt atacaatata aaaaatacat
      301 ttacttagaa gtattattat atttggattt ttggttttta taattttttt atatttaaac
      361 atagctaaaa ataaaagatt acgaaagcta agtagagttt attttatttt aataaataat
      421 aaagctattt ttctatatat tggcataata tatgcttatt taactatgaa attaaaatta
      481 aataggatta atgaggagga aaaaaatggg aagtaatgaa ctgaaaaaga ctcttggcgt
      541 atcagcagca ttatcaactg ttgttggttc cgttatagga gcgggcgtat tttttaaacc
      601 acaagcagtc tatacattaa ctggaggagc tccaggtctt ggtatattgg catggttaat
      661 agctggaatc ataactataa cagctggtct tacagctgca gaggtatcag ttgcgatacc
      721 aaaaactggt ggaatgatgg tatatataaa agaaatttat ggagaaaaat taggtttttt
      781 aactggatgg atgcaaattg tattatttta tccagggatg atggcagcat taggtgttat
      841 atttggagaa caagcatcag cactaattgg tagtccatca cttttacttc caatagcaat
      901 tggaattata gtaatagttg cagggcttaa tatgttaggt tcaaaaactg gaggagtcat
      961 acaaactgtt tctacaattt gtaagttaat accacttatt ttaataatgg ttgttggatt
     1021 tattaaaggt ggtggaaata atccaatact tacacctatg gttggtgaag gattaagcct
     1081 gggtagtgta ctaggtcaag ttttaattgc tatattattt gcttttgatg gatggatgaa
     1141 tgttggtact ttagctggag aaatgaagaa tcctggaaaa gaccttccaa aagctataat
     1201 aggtggattg tcagttgtta tggctgttta ttttataata aatttagcgt atctttgggt
     1261 attaccagct aatgaattag caaattatgc ttctcctgca tcagcagttg ctgaagttat
     1321 atttggttca atgggtggaa aaataatatc tgtaggtata ttaatttcag tgtttggagc
     1381 attaaatgga tttttactaa ctggttcaag ggtggcatat actttagcta cagataagac
     1441 tttaccaaag tatggtatat tttctaaatt aaattctgct caagttccag caaatgcaat
     1501 agcattagta tctgttattg catctatata tgctttgtca ggtcaattta atttattaac
     1561 tgacttagct gtatttgcta cttggatatt ctatgtatta acttttatag gggttatgaa
     1621 acttagaaag actcatccaa atataccaag agagtataaa gttccattat atcctattgt
     1681 tcctataata gctatagcaa gtggtatatt tgttgtagtt aatcaattgt gttttgcagg
     1741 tatgaaaact actatgatat ctataggagg tcttgtaata acagctatag gcttaccagt
     1801 gtatgcttat atgactagag gagtaaaaag ataaaccaag tagtttacaa atgcttcata
     1861 attaaaataa aagagactgt ctcaaataga gataagtctc ttttttattg ttaaaatggt
     1921 aaagatatgt ttaattttac aaaaaaagag cgttccatga actaaaaagt ttattttaag
     1981 gtattcattt tatttttagt tttttgatta taaaattaaa catctaaaaa attatttatt
     2041 ttaaaatact ttattttaaa gtgtttttta tcaaactaag tggtatctgt acaacaaata
     2101 ttatacatag cttttatgaa aattaaatct ttctgttata tataatagaa tattgtatta
     2161 tatagaaaat attacctgat taatatagtg atttataaat gagattagaa aattttattt
     2221 gataacaaaa attagataat atgaatatat aatgtatgta ttaaaaatgt ggcaaatagt
     2281 tgttttgcta tttattattt gtttaatatt tctaatttat aaaaaaaaaa ttataaattt
     2341 taaaaattat aaatgacatt ttaactagaa ttaattgtaa aaaacactat ataatactca
     2401 attttcaaca ttctatacaa ttatacagaa attatacagc ataataatca ccgaaataac
     2461 aaattttaaa aattaagcaa aactttttgt cgaagttcaa cgtctatata tatgtagtgt
     2521 aaatttttgg gataaaatac tacaaaaata taaatgtaaa aatatagtaa tattggaggt
     2581 cgaacgatga gaaataaaaa gaaaaaaata aatagaaaga agttgtattt gcttttaagt
     2641 gctattgtag tgtgtctggc ttttatagta gttggtgttc gcgtcagctc tttaaatatg
     2701 aaggaaaatg aaattagtag aaatgcaaaa ctgtcaagtt ctactattac agatatagta
     2761 tctaatacat caatagaagt tagtaaaggg ccaagtaaaa gttctggaaa aatagcatac
     2821 ataactatag atgatggtcc atctaaattt actgacgaga tgataaaaac tttaaataaa
     2881 tacaatgtta aagcaacttt ttttatgata gatgggaata tgaaggaata tccacagcaa
     2941 gttaaaaata taattaaaaa tgggaacaca gcaggttttc atagtgtatc acatgatatt
     3001 cacaagcttt atgttactag tacatcagca aaagaggaat ttgatacaaa tgatcaaact
     3061 ttttataaga taactggtaa acattcaaaa gtaataagaa taccttatgg aagcaaacca
     3121 tatacaccac aagcctctta tcaggcttta gttgatgctg gatataaaat ttgggactgg
     3181 gacttagata cagaagactg gagatctaat tcttctcaaa ttgtacaaaa tgtaaaaaat
     3241 catattaaga atagaaaagg tgaagataaa gaccaacttg tagttttaat gcatgagaaa
     3301 aaacagagtg cagaagcttt agattcagtt ttaaaattct tatcagatga aggttatgaa
     3361 tttgcgccag tagatcaaaa ccaaatacca aaaaattatt ggttacgtaa tttagagtag
     3421 ttaaaatata agaatattga ttgatatttt tagaaattga gaataaaaat gagtgaggtg
     3481 taggtatatt gaataaaaaa ctttatatag gaatggtcgg aatattgtct ttgatgatgg
     3541 ttggttgtaa taaaagttta gcaaaagtaa atgatgtgga aatcacaaaa gaacagtaca
     3601 aaaaaacaaa agcagtttta tctgctacta ataattatat aaatgggcag tctttagatg
     3661 aattagaaaa aactttggat aaaaaaggta gaaataaatt agaaaatgtt ataatatcgt
     3721 ttatggtgga taatgaactt ttatatcaag aggctaagga taaaggacta actccaagta
     3781 aaagtgaagt agactcaaaa tatcaagaac tagaagataa gatgaatttg aatacaagct
     3841 ataaggaaaa aatggacaaa gcaggtgttg ataaagatta tttaaaacaa gaaatatcta
     3901 gagatttagc aatagataaa aataaaaagg cctttgaaga tagaataaac ataagtgata
     3961 atgatatgga agcctactat acaagtcata aaaaagattt taatgtagaa gaagtaagtg
     4021 cttctcagat acttatatcg actttagata aaaataaaaa agaagtaagc aaagataaaa
     4081 aagaagcttt gaagaagaag gcagataata tattgactaa aatcaaaaat ggagaaagtt
     4141 ttgaaagttt ggctaaaaaa tattcggatg ataaagcaac tggaaaaaat ggaggacagc
     4201 taggatattt tacaaaggat gataaaaatg ctgagtttac aaaggaagtg ttcaaattaa
     4261 agaaaaatga agtttcaaat gtgtttgaaa ctagttatgg atatcatata gtcaaagtta
     4321 ctgataaaag agaaagacaa aaaagtttta atgagtgtca gagtttaata agagaatcta
     4381 ttttaaatga aaagtatatt gagcatataa aaaaactgaa tgaagatgct aaaatagaca
     4441 gatagaattt ctaacagctc aatcctagcc tgtaatcgga gggagatttt acaggaatgt
     4501 ttaagagttt aaagagaacg aaagttgaga aatacattat cgataataaa gactcttttt
     4561 atagaatagc atatagttat acgaagaatg aagaagatgc cttagatgtg gttcaagaag
     4621 ccatgtataa ggcactatac tcagtggaaa atattaaaga agtaaattat ataaagacat
     4681 ggttttataa aattttagtt agaacgagta tagattttat tagaaaaaac cgtaaatata
     4741 ataatatgac agatattgac cttatagatg agactggaga gtatgataaa tatactgatt
     4801 tggatttaag aagagctttg gaagaattac ctattgaata caaatctatt ataatattaa
     4861 gattttttga agatttaaag attgaagaag tagcaataat attggatgaa aatgtgaata
     4921 ctgttaaaac taggttatat actgctttaa aaaaactaaa attaaaaatt gaagagtagg
     4981 gataaaaaga atgacaagca aagaaaggtt aaataagtta aaagatgagt atcataaaat
     5041 tccaataccc aagaaattag atactataat aaatcatgaa aaaatagaaa acatatatcg
     5101 agagaaaaat aaaaaagtaa atagattaag atttaaagtt gcaatagcct ttgcatgtat
     5161 atttacagta ttagtaaata taagtcctgt atttgcagac aatttttcta agatacctgt
     5221 aattggagca atagtagaag taataactat aaaaaattat agtttaaaaa gtgaaaatta
     5281 tgaagctgag attgatattc ctaaaatacg aggtttaaaa gataaaaact tagaacaaag
     5341 attaaacagt agttttatgg aagatggaaa aaggctttat catcaattcc aagagagaat
     5401 ggagaagata caatcatcaa agaataaagg atataaatct ttaagtttga gttatagtgt
     5461 aaaaaataat tctaaaaaat ttctatcaat agagatgaca aaaaatgaga tagaggcttc
     5521 atcatatgtg agtaaggtac attatactat tgataaaaaa agacaaatag ttttgacttt
     5581 gccaatgctt tttaaagatg ataagtatat aaaagttata agtgataata taaaagaaca
     5641 aatgagagaa caaatgaaaa aggatagtac aaaatcctat tttatagatc aaaaaaaaga
     5701 cttgcctgtt gaagatttta aaacaattaa taagtatcag gatttttatt ttaataaaaa
     5761 tgaagacctt gtaatttgtt ttgatgaata tgaagtagca cctggttata tgggcgcagt
     5821 tgagtttgta ataccatata aagtaataaa agatttgtaa attgaatagt agtttatata
     5881 taaatctttt aaggaggaca atatgactac atataaaaaa cttaaaaaat ctatatttaa
     5941 a
//
LOCUS       DAEPHU010000138         5823 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 01A10CD0081
            SAMN05941466-rid12468953.denovo.140, whole genome shotgun sequence.
ACCESSION   DAEPHU010000138 DAEPHU010000000
VERSION     DAEPHU010000138.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941466
            Sequence Read Archive: SRR6291087
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 5823)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5823)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068158.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 22:43:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,892
            CDSs (total)                      :: 3,805
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 87
            rRNAs                             :: 8, 1, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 55
            CDSs (without protein)            :: 55
            Pseudo Genes (ambiguous residues) :: 0 of 55
            Pseudo Genes (frameshifted)       :: 21 of 55
            Pseudo Genes (incomplete)         :: 28 of 55
            Pseudo Genes (internal stop)      :: 16 of 55
            Pseudo Genes (multiple problems)  :: 8 of 55
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5823
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941466-rid12468953.denovo.140"
                     /strain="01A10CD0081"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            112..729
                     /locus_tag="KR231_003638"
     CDS             112..729
                     /locus_tag="KR231_003638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH0005963.1"
                     /translation="MISLINISKKFKDKSIIDKFNLEISKGEFVAITGNSGSGKTTLL
                     NIMGLLEKPNSGDIIINNIKNPNSKQIRILQRDFYGYLFQNYALIENENVENNLKIAL
                     KYQKNINHNKKINYALESVGLRKYNKKKIYELSGGEQQRVALARVILKECEVIFADEP
                     TGNLDKKNRDIVFDILKSLNKNGKTIVFVTHDLELSEQADRVIKL"
     gene            918..1262
                     /locus_tag="KR231_003639"
     CDS             918..1262
                     /locus_tag="KR231_003639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000212737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkylphosphonate utilization protein"
                     /protein_id="HBH0005964.1"
                     /translation="MENLPNCPKCNSEYTYEDGTLLVCPECSHEWALGLGAEEDSNII
                     KDVNGNVLNDGDSVTVIRDLKVKGSSSSIKIGTKVKNIRLIHDSSDGHDIECKIDGFG
                     AMKLKSSVVKKA"
     gene            1832..2698
                     /locus_tag="KR231_003640"
     CDS             1832..2698
                     /locus_tag="KR231_003640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pentapeptide repeat-containing protein"
                     /protein_id="HBH0005965.1"
                     /translation="MIDIHKNIYDNKLFEELKIDCKKCFGLCCVALYFSASDGFPIDK
                     ESGKPCINLQPDFKCSVHNSLMKRGFKGCTAYDCFGSGQKVAQVTYKGIDWMQSSELT
                     NQMSEVFLIMRQLHEMLWYLKEASVLNISDTIKSKIDLIIEETEKITNMSPEQIINLD
                     IISHRIKVNLLLSQASESVMGKVKSFIKTSTLKNMKKLSKNIDLIGADLRKINLIGAD
                     LRGRFLIAANLRNTDLSGANLIGADLRDCDIRGANLENSIFLTQLQVNTAKGDSSTKL
                     PASLIRPKYWEK"
     gene            2811..3215
                     /locus_tag="KR231_003641"
     CDS             2811..3215
                     /locus_tag="KR231_003641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YmaF family protein"
                     /protein_id="HBH0005966.1"
                     /translation="MSYQNYKCERDYVYDDYKYNKCNKCYNDYEEMTHVHEYSESVKL
                     AEECEDRHNHRAAGVTGEAIPINGGTNHVHKINDNVDFLDHFHKICVTTGPAIRIPGT
                     DKHIHLICGETTVNDGHCHKFLFTTQIEAPLV"
     gene            3382..3831
                     /locus_tag="KR231_003642"
     CDS             3382..3831
                     /locus_tag="KR231_003642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011862010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBH0005967.1"
                     /translation="MKSGIILEMKQINSTEYDEMLQVWESSVRATHDFLTEKDIESLI
                     PLVEIGLKEVENIVCIKDNDIIKGFIGIDKDKIEMLFIEDKYRGNGIGKKLIKYAIDK
                     YNVKYVDVNEQNKKAVGFYIHLGFKVFDRSEIDGQGNPFPILHMKLI"
     gene            complement(3987..4364)
                     /locus_tag="KR231_003643"
     CDS             complement(3987..4364)
                     /locus_tag="KR231_003643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HBH0005968.1"
                     /translation="MLTPYLIFNGTCEKAFNFYAEAFGGGKTIFARLDSNPNNPIMHA
                     SVTFTKYEGCIMGADTDKPVVISGMAICVVLPSREAIEEISVKLAEGGTLVQEFLPHP
                     PPHQNDGAAEVLDRYGYTWYLST"
     gene            4626..5543
                     /locus_tag="KR231_003644"
     CDS             4626..5543
                     /locus_tag="KR231_003644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011862008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2268 domain-containing protein"
                     /protein_id="HBH0005969.1"
                     /translation="MVNMNIIEIRSDKIYKKIMDAPINKKEDIYRYELMKPFEFKWKC
                     MNVPIVARQKGGYDVIIASEMLGVLSPKDIDEKQKKNINVLSADKIWATCKETIENSI
                     NAFIKEGYDLNIKDYKYSILLANPNSPYTILSDGYWGDGGIPGYIFLSLVPNEYTINR
                     LPVLIAHECNHNIRFQFIEWNNNITLEEMMINEGLAENFATWMFGEEMLGPWVSRTDI
                     ETLNTYIKPIIKSALKETGFQNITSYLYGDDIAKMQGYFPVGLPYCAGYACGYYMIKY
                     YLEKTNKSIIEATLLPYSEIIEAVKEFWE"
BASE COUNT         2360 a          607 c          926 g         1930 t
ORIGIN      
        1 tcttatttgg acttctaata ttagttatag aagtaattgt atctattgta ttagacaaga
       61 ttatctcaaa tagttcattt aataaaatta taaaaggaga acattaaaaa gatgatttca
      121 ttaataaata tatctaaaaa atttaaagat aaatctataa tagacaaatt taacctagaa
      181 atttctaagg gcgagtttgt agcgataaca ggaaatagtg gttcaggtaa gacaacttta
      241 cttaatataa tgggattatt agaaaaacct aattctggtg atattataat aaataatata
      301 aaaaatccaa atagtaaaca gataagaatt ttacaaaggg atttttatgg ctatctattt
      361 caaaattatg ctttaattga gaatgaaaat gttgaaaata acttgaaaat tgctttaaag
      421 tatcaaaaaa atatcaacca taataaaaaa ataaattacg cacttgagtc tgtaggtctt
      481 agaaaataca ataaaaaaaa gatatacgaa ttgagtggag gagaacaaca aagggtagca
      541 ttagcaagag taatattaaa agaatgtgaa gtaatatttg cagatgaacc tacaggtaat
      601 ttagataaaa aaaatagaga catagtattt gatatactta aaagtctaaa taagaatggt
      661 aaaactatcg tatttgtaac tcatgattta gagttatcgg agcaggcaga tagagttata
      721 aaattgtaat aatatcaact ataataaata taagaaagag attacagcta aatcaagttt
      781 aataataata cgaatagaat ttaaacatta agtaaattag tagtttgtaa atataagtat
      841 aatatgatat cataaaggct caaaagaaat tttatataat aagaaatcta aaaataacaa
      901 atggaggaca tataaagatg gaaaatttac caaattgccc gaaatgtaat tcagaatata
      961 cttatgaaga tggaactctt ttagtttgtc cagaatgctc tcatgagtgg gcattaggat
     1021 tgggagctga agaagattca aatattatca aagatgtaaa tggaaatgta ttaaatgatg
     1081 gagattctgt tacagtaatt agagacctta aagtaaaagg aagttcatca tctataaaga
     1141 ttggaacaaa agtgaaaaat atccgtttaa tccatgactc atcagatgga catgatatag
     1201 aatgtaagat agatggtttt ggagctatga agctaaagtc ttctgttgtt aaaaaagcgt
     1261 aatattataa ataagctgta gtgtttattg tttttcagta cagtataaaa ccataagaat
     1321 ctattaagta ataaaagttt gtttatttat ctttatattt tcttatggtt ttattaaata
     1381 taaattttat tgaacaccaa aatattctct cctctacaaa taagccaatc ttatttaaat
     1441 taatatactt tgtactattt atactgaaat tgtaaattta aatgctatgt tatttaggtt
     1501 tgtatagtta atttatatat ttctgatttt ataaattgta tttattatta tatcttgatt
     1561 ctaaaatcat taaaaatttc aacttctata aagatttaca atttatcaaa tacattatga
     1621 gtatataaac aatttattat tacagtgcta catttaaaat aagtcttagt ataaaggtat
     1681 tgttacaagt ataaagaaac ttatgtatgc tattggaata aataatacct taaattataa
     1741 taaagaataa gaactgttaa ataagggact tgattatcat ttagttatag ataatataat
     1801 attaaaaata aagtttaaga ggagaaaaaa tatgatagat atacataaaa atatatatga
     1861 taataagtta tttgaggagc taaagattga ctgtaagaag tgctttggac tttgctgtgt
     1921 agctctttat ttttctgctt cagatggatt tcctatcgat aaggaatcag gaaaaccctg
     1981 tattaattta caaccagatt ttaaatgttc tgtacataat agtcttatga agcgaggttt
     2041 taaagggtgt actgcatatg attgttttgg ttcaggtcaa aaagtagcac aagtaacata
     2101 taaggggata gactggatgc aatcatcaga actaacaaat caaatgtctg aagtgttttt
     2161 aattatgaga caattacatg aaatgttatg gtatcttaaa gaagcatctg tattaaatat
     2221 atcagataca atcaaatcaa aaattgattt aataattgaa gaaactgaaa agataactaa
     2281 tatgagccca gaacagataa ttaatttgga tatcatatca catagaataa aggttaattt
     2341 attattatca caagcgagtg agtctgtgat gggaaaggtt aaatcattta tcaagacttc
     2401 tactcttaaa aacatgaaaa aattaagtaa aaatatagat ttaataggag cagaccttag
     2461 aaaaataaat ctaataggag cagatttaag aggtagattt ctaatagcag caaatttaag
     2521 aaatacagat ttgagtgggg caaatttaat aggagcagac ttaagagatt gtgatattag
     2581 aggtgctaat cttgaaaata gtatattttt aacacaatta caagtaaata ctgcaaaagg
     2641 agattctagt acgaagttac cagcttcact aatacgccct aaatactggg aaaaataatt
     2701 aaattaatac ataattttac aaaacatgaa cttttttgac tttaattcat attatacatt
     2761 agagattctt tacaagaatt tcttaatata atatagggag agatataaaa atgagttatc
     2821 aaaattataa atgtgaaaga gattatgtgt atgatgatta taaatacaat aagtgcaaca
     2881 agtgctataa tgattatgag gaaatgacac atgttcatga atattcagaa agtgttaagt
     2941 tagcagaaga atgtgaggat agacataacc accgtgcagc aggggttact ggtgaagcta
     3001 taccaataaa tggaggtaca aatcatgttc ataaaataaa tgataatgta gatttccttg
     3061 accatttcca taagatatgt gttacaacag ggccagcaat tagaatacct ggaactgata
     3121 aacacattca cttaatatgt ggagaaacta ctgttaatga tggtcattgt cataaattcc
     3181 tttttactac tcaaatagaa gcacctttag tataagctga tgtgaattat tgtagtgaat
     3241 ttgctagatt atagtataat aatatataat agataatatt taaacttaat gaggactatg
     3301 atatttaacc ttcgtagtcc tttctaagtt ttgtataaaa aagtgttatg caattaaaag
     3361 tgatataggg aggaaatttt tatgaaatct ggaataattc ttgaaatgaa acaaataaat
     3421 tcaacagaat atgacgaaat gttgcaagtc tgggaatcat cagtaagagc aacgcatgat
     3481 tttttaacag aaaaagatat tgaatctttg ataccattag ttgagattgg acttaaagaa
     3541 gtagaaaata tagtttgtat aaaagataat gatataataa agggctttat aggaatagat
     3601 aaagataaaa ttgagatgct ctttatagaa gataaatata gaggaaatgg tattggtaaa
     3661 aaattaataa aatatgctat agataaatac aatgtaaaat atgttgatgt aaatgagcag
     3721 aataaaaaag ctgtaggatt ttatattcac ttaggattta aagtgtttga taggtctgaa
     3781 atagatggac aaggtaaccc atttccaata ctacatatga aattaattta aagttatact
     3841 tctcatttat tcgcaaaaat atttacttaa atttttatac aaataaaagt cgtgacagtc
     3901 ttaggacacg acttttttac tacactatta aattgaaatt tatctgttct atattatgat
     3961 tattagatgt cgttttttta ttttaactat gtacttaaat accaagtata cccataccta
     4021 tcaagtactt cagcagcgcc atcattttga tgtggtggtg ggtgtggtaa aaattcttgt
     4081 acaagtgtac caccttcggc aagttttaca gatatttctt ctatcgcttc tcgagatggt
     4141 agaacaacac aaatcgccat gccagaaatt acaacaggct tgtctgtatc cgcacccatt
     4201 atacaacctt cgtattttgt gaaagtaaca cttgcgtgca taataggatt gtttggattg
     4261 ctgtctaatc gcgcaaatat agtttttcct cctccgaaag cctcagcata aaaattaaat
     4321 gctttttcac aagtaccatt aaatattaaa tatggagtta gcatgaccaa tatatcctcc
     4381 ttgatataga ataatttata gttgcacctg ataatctaaa ttatgattta gtaaattgta
     4441 tcatagggaa accttgaagt atataatttt ttattattat attatacaaa tttattaatt
     4501 taaaaaaatg ttatatgtac ggaaggttta caggataaaa tataataaaa agattaaggt
     4561 gacattataa aaaatgtata ttgacattga cgctacgtaa ttgtatatac tttgtcttaa
     4621 aggagatggt aaatatgaat attatagaaa ttcgctcaga taaaatatac aagaagataa
     4681 tggatgcacc aataaacaaa aaagaagata tatacagata tgaattgatg aagccttttg
     4741 aatttaagtg gaagtgtatg aatgttccaa tagttgctag acagaaaggt ggatatgatg
     4801 taattatagc aagtgaaatg ttaggggttt tatcgcctaa ggatattgat gaaaaacaaa
     4861 aaaagaatat aaatgtgtta tctgctgata aaatttgggc cacttgtaaa gaaaccatag
     4921 aaaactctat aaatgctttt ataaaagaag ggtatgattt aaatattaag gactataaat
     4981 attcaatatt attggcgaat ccaaatagtc cttatacaat attaagtgat ggatactggg
     5041 gtgatggtgg gattcctgga tatatatttc tatcattggt tcctaatgaa tatactatca
     5101 atagattacc agtattaata gcacatgaat gtaatcacaa tattagattt cagtttatag
     5161 agtggaataa taatataaca ttagaagaaa tgatgataaa tgaaggtctt gcagaaaatt
     5221 ttgcaacatg gatgtttgga gaggaaatgt taggaccttg ggtcagtaga acagatatcg
     5281 aaacattaaa tacttatata aagccaataa taaaaagtgc tttaaaagaa actggatttc
     5341 aaaatataac atcttatctt tatggtgatg atatagctaa aatgcaagga tattttccag
     5401 tagggttgcc ttattgtgca ggatatgctt gtggatatta tatgattaag tattatttag
     5461 aaaagacaaa taaatcaata atcgaagcga ctttattgcc ttatagtgag ataatcgaag
     5521 cagtaaaaga gttttgggaa taaattttat aaattgcata atttgaaata aattatgcaa
     5581 ttattttatt tttaagaaaa aataaattga caataattta taagaaatat acaataatat
     5641 atataaagaa atatttcaat atttaaaagt tttaagattt catatctaga gtacctaaca
     5701 ttacatgtta gtttcttgtt acttatctaa ttactttata tttcgtagtt atatataaaa
     5761 ttactataaa aaatgaaata tattaaacaa tcaactaaaa aatgaaatat taataaaaaa
     5821 aaa
//
LOCUS       DAEPHU010000139         5753 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 01A10CD0081
            SAMN05941466-rid12468953.denovo.141, whole genome shotgun sequence.
ACCESSION   DAEPHU010000139 DAEPHU010000000
VERSION     DAEPHU010000139.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941466
            Sequence Read Archive: SRR6291087
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 5753)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5753)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068158.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 22:43:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,892
            CDSs (total)                      :: 3,805
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 87
            rRNAs                             :: 8, 1, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 55
            CDSs (without protein)            :: 55
            Pseudo Genes (ambiguous residues) :: 0 of 55
            Pseudo Genes (frameshifted)       :: 21 of 55
            Pseudo Genes (incomplete)         :: 28 of 55
            Pseudo Genes (internal stop)      :: 16 of 55
            Pseudo Genes (multiple problems)  :: 8 of 55
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5753
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941466-rid12468953.denovo.141"
                     /strain="01A10CD0081"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            complement(523..2658)
                     /gene="rnr"
                     /locus_tag="KR231_003645"
     CDS             complement(523..2658)
                     /gene="rnr"
                     /locus_tag="KR231_003645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease R"
                     /protein_id="HBH0005970.1"
                     /translation="MIPGLKESLLGLINESAYNPLKKEELAEIFDIHSSEMPMFYNFL
                     NELEEDGYICFTKKGKIVSPNQMGYFVGKFVSHKKGFGFVESDVEYTQDLFISSDNIN
                     GAMHNDRVMAEIVVPATEEKRAEGRIVKVIKREITRIVGTFQSSKTFGFVTPDNKKFT
                     KDIYIPKKHFSGAVDNDKVVCEITVWPQEDRKPEGKIIEILGQKGERGVEIDSIIREH
                     GLPEEFPKKVLQEAEAVAVEIPQEEIKRRRDLRDLNIFTIDGDDAKDLDDAISIEVLP
                     NGNFKLGVHIADVTHYVREKNKLDKEALKRATSVYLVDKVIPMLPKTLSNGVCSLNPF
                     EDKLTLSIFMEIDHKGNVVKHEICESVINSKARMTYTEVSDILEKDDEKLKKTFEHVV
                     EDFKNAEILARILMSRREKRGAIDFNFPEAKIILNGKGEVVDIKPYERRISNKIIEEF
                     MLISNETIAEHFYWMGIPFVYRIHETPSLEKMEELSKFISTFGYIIKGDKEEVHPKAL
                     QGIIEKIKGKKEEGAISTIMLRSLKQAKYSPECSGHFGLAAKFYCHFTSPIRRYPDLQ
                     IHRIIKESLNNKISGKRQEQLTTIVDYASVQSSEKERKAELAERDVHDFYKALYMKDK
                     VGQEFEGVVSSVTSFGIFVELDNTIEGLIRLANMNDDYYIYDESSYSVLGERTKKSYK
                     IGDLVKIKVESVNVDFKEIDFEIVEKIEE"
     gene            3251..3865
                     /locus_tag="KR231_003646"
     CDS             3251..3865
                     /locus_tag="KR231_003646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA alkylation repair protein"
                     /protein_id="HBH0005971.1"
                     /translation="MEEVIAKIITIENGFKEIENIAKKIVKNNDSKKCYYLSIYLYRS
                     EYYQVRELAVFILGFISVTISEALLFLKDNVSKDENWRVQEILAKSFDYYCSEVGYEK
                     ALPVIKEWLNSDSPNIKRAVTEGLRIWTNRDYFKSNPDVAISLLSSLKEDDSEYLRKS
                     VGNALRDISKKYPDLVKKELDSWDISNKKVEFVYKLASKCILAK"
     gene            3883..4245
                     /locus_tag="KR231_003647"
     CDS             3883..4245
                     /locus_tag="KR231_003647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBH0005972.1"
                     /translation="MKLRDEYTCPLELTHDMIKGKWKSIILWRLRIGPTSLSKLEKEI
                     NGINQKMLLEQLKELIEFGLVDKKTYEGYPLKVEYSLTPIRGKQILDALAIMQDIGIS
                     FMLDNGMEDILKEKGVLK"
     gene            4351..4848
                     /locus_tag="KR231_003648"
     CDS             4351..4848
                     /locus_tag="KR231_003648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbhB/YbcL family Raf kinase inhibitor-like
                     protein"
                     /protein_id="HBH0005973.1"
                     /translation="MKVTSTGIVNGVIEDKYGKRGTQFNEGGMPTYSLPLKFEDAPKN
                     TVSFAVFLEDKDSVPVCGFAWIHWLAVNITKDELNENESVTATDFVQGTTSWHGKLGG
                     LDRLEASVYGGMAPPDRPHVYEIHVFALDTILDLEKGFYMNEFFKAIEGHVLDTFTLK
                     GSYSN"
     gene            5652..>5753
                     /locus_tag="KR231_003649"
     CDS             5652..>5753
                     /locus_tag="KR231_003649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBH0005974.1"
                     /translation="MIAVKKAYKFRIYPNKKQQELINKTFGCCRFVYN"
BASE COUNT         1935 a          857 c          737 g         2224 t
ORIGIN      
        1 ttttcaatta gtcacttcta ttaaacattt cttaattatt tatttttcaa ttagccactt
       61 ctattaagca tttcttaatt acttattttt caattagcca cttctattaa gcatttctca
      121 attacttatt tttcaattag ccacttctat taagcatttc ttaattactt atttttcaat
      181 tagccacttc tattaagcat ttcttaatta cttatttttc aattagccac ttctattaaa
      241 catttcttaa ttatttattt ttcagttggc tttttctatt aaatgtttct taattactta
      301 tctttcagtt agctctttct attaaacatt tctcaattac ttatttttca attagctact
      361 ttcattaaat atttcttaat tatttatctt tcagttaact atttccatta gatatttctc
      421 aattacctat ttttatcatt tattttatag agtattgtgc actatatatt tatacatatc
      481 ataaatacta caacttgtta tctcttattt tagctgtttt atctactcct ctattttttc
      541 aactatctca aagtcaattt ctttaaaatc tacattaaca ctttcaacct ttatcttaac
      601 aaggtcacct atcttatatg acttcttagt tctttctcct aaaacactat aagaactctc
      661 atcataaata tagtaatcat cattcatatt tgcaagtctt atcaaccctt ctatggtatt
      721 atctaactca acaaatattc caaatgaagt tacgctagat acaacaccct caaattcttg
      781 accaacttta tccttcatat aaagagcctt atagaaatca tgtacatctc tttcagctaa
      841 ctctgccttt ctttctttct cggatgattg aacagatgca taatccacta tagtagtaag
      901 ctgttcttgt ctttttccac ttattttatt atttaaagat tcttttatta ttctatgaat
      961 ttgaaggtca ggatatcttc ttattggtga agtaaagtga cagtagaatt tagctgctaa
     1021 tccaaaatgt ccactacatt ctggtgagta cttagcttgt tttaaagaac gaagcattat
     1081 agtactgata gctccttctt cttttttgcc ctttattttc tctattatac cttgtaatgc
     1141 ttttggatgt acttcctctt tatcaccttt tattatatat ccaaatgtag atataaactt
     1201 actcaattct tccatttttt ccaaagatgg tgtctcatgt attctataca caaacggtat
     1261 tcccatccag taaaaatgtt cggcaattgt ctcattactt ataagcataa attcttctat
     1321 tatcttatta gatattcttc tttcatatgg ctttatatct acaacttcgc cttttccatt
     1381 tagaattatc tttgcctctg ggaaattgaa gtctatagct cctctttttt cccttcttga
     1441 cataagaatc ctagctaaaa tttcagcatt tttaaaatct tcaacaacat gttcaaaagt
     1501 ctttttaagt ttttcatcat ccttttctaa tatatcagat acttctgtat aagtcattct
     1561 agcttttgaa tttattacag attcacatat ttcatgttta accacatttc ctttatggtc
     1621 tatttccata aatatagaaa gagttagctt atcttcaaat ggatttaagc tacatactcc
     1681 atttgaaaga gtttttggca acattggaat tactttatct actaaataaa ctgatgtagc
     1741 tctttttaag gcttccttgt caagtttatt tttctctctt acataatgtg taacatcagc
     1801 tatgtgaact cctagtttga agtttccatt aggtaatact tctattgata tggcatcatc
     1861 taagtctttt gcgtcatctc catctatagt aaatatgttt aaatctctta aatctcttct
     1921 tctttttatc tcttcttgag gaatctcaac agctacagct tctgcttctt gcaatacttt
     1981 ctttggaaat tcttctggaa gaccatgttc tcttattata gaatctattt ctacgcctct
     2041 ttcacctttt tgacctagta tctctataat tttgccttct ggttttctat cctcttgtgg
     2101 ccatactgta atttcacata ctaccttatc attatctact gctccactaa aatgtttttt
     2161 aggtatatat atatctttag taaatttctt gttgtctggt gttacaaatc caaaagtttt
     2221 acttgattgg aaggtaccta ctattctagt tatttctctc tttattactt ttactattct
     2281 tccttctgct ctcttttctt cagttgcagg tactactatt tctgccataa ctctatcatt
     2341 atgcatagca ccatttatat tgtcacttga gataaataaa tcctgtgtat attcaacatc
     2401 agattctaca aatccaaaac cctttttgtg tgatacaaat tttccaacaa agtatcccat
     2461 ttgattggga gatactattt ttcctttttt agtaaagcag atataaccat cttcttctaa
     2521 ttcatttaaa aaattataaa acattggcat ttctgatgaa tgtatatcaa atatttctgc
     2581 taattcttct ttttttagag gattatatgc actttcattt attaatccta gcaaactttc
     2641 tttaagtcct ggtatcattt ttccctcctg ttttactttt cattatatta ttatttatat
     2701 tgtcttttat atttcttcag acaaaacatt ttttacttat cacataattt tctatatttt
     2761 cttattatta taagttaaaa ttacttattt atatttttga tttaatgtaa tctttgtcat
     2821 actaacttca aacaaattat gatgttttat aaattatttg taaatatcat tataattact
     2881 taagttattc tttatcataa ttgcttaaat tactctttat cacctaatta tacaccatca
     2941 aataggattg gtaaaatatt catctcatat aagtattact atataataat ttattctatt
     3001 agtatactca aatcatgtaa aatttatata actcaattaa ttttttaaat acaactttat
     3061 aatataaaac ttataataaa agtaaattta tatgttaaat gaggttgatt ttttattatt
     3121 ttttatttat gctagtacta aagacttgca aacgtttttt gacaagtctt tattttgtct
     3181 aaattaaaca aactttttta caaataaata cataaaattt aaactaatct atttattgga
     3241 ggagataaaa ttggaagaag taattgcaaa aattattact atagaaaatg gattcaaaga
     3301 aattgaaaac attgctaaaa aaattgtaaa aaataatgac tcaaaaaagt gttattatct
     3361 atcaatctac ttatataggt cagaatatta tcaagtaaga gaattggctg tgtttatact
     3421 tggttttata tcagtaacta tttctgaagc tttgttattt ttaaaagata atgtgagtaa
     3481 agatgaaaac tggagagtac aagaaatact agctaaatca tttgattatt attgcagtga
     3541 agtaggatat gaaaaggcac ttcctgttat aaaagaatgg cttaattctg atagtccaaa
     3601 cataaaaagg gctgtgacag aaggtcttcg aatttggact aatagagact attttaaatc
     3661 taatcctgac gttgctatat cactactttc tagtttaaaa gaagatgata gcgaatactt
     3721 gagaaagtct gtaggtaatg ctcttagaga tataagtaaa aaatatccag atttagtaaa
     3781 aaaagaatta gattcatggg atatatcaaa taaaaaagtt gagtttgtat ataagcttgc
     3841 ttcaaaatgt atcttggcaa agtaaaatgg aggtgaactt atttgaaact tcgtgatgag
     3901 tatacttgcc cattagaact aacacatgat atgataaaag gcaaatggaa atctattata
     3961 ttatggagat tacgcatagg accaacttcc ttatcaaaac ttgaaaagga aatcaatggt
     4021 attaatcaaa agatgttact tgaacaactt aaagaattaa ttgaatttgg tcttgtagat
     4081 aaaaagacat atgaaggtta cccacttaaa gtcgaatact cacttacacc tattcgaggg
     4141 aaacaaatat tggatgcttt ggctataatg caagatatag gaattagctt tatgttggat
     4201 aatggtatgg aagatattct taaggaaaaa ggtgttttaa aataaataga tacccacaaa
     4261 aaagtaagta atttaccatt attttcaact ggtatataat taaattatag atatattcta
     4321 ttaatttatt ataataggag gtaaattatt atgaaagtaa ctagtacagg tatagtaaat
     4381 ggtgttatag aagataaata tggtaaaaga ggaactcagt tcaatgaagg tggtatgcct
     4441 acatattcac tacctctaaa gtttgaagat gctccaaaga atacagtatc ctttgctgta
     4501 tttttagaag ataaagactc tgttcctgta tgtgggtttg catggataca ttggttagct
     4561 gtaaatataa caaaagatga gttaaatgaa aatgaaagtg taacagctac tgattttgta
     4621 caagggacta ctagttggca tggtaaacta ggaggtcttg acagattaga ggccagtgta
     4681 tatggtggaa tggctcctcc agacagacct catgtctatg aaatacatgt atttgcactt
     4741 gatactatcc ttgaccttga aaaaggattc tatatgaatg aatttttcaa agctattgaa
     4801 gggcatgttt tagatacatt tacactaaaa ggaagttatt ctaattaatt aggttgacta
     4861 tagctaatca ttaattaaat gatacattta attgatgatt agcttaattg ttattagaat
     4921 attttctgca ctttatctta atatatattt tagttgactg gtattttaat ttctattaga
     4981 ttattatcaa tttatataaa ttgattaaaa aatagctacg cacactcgtg actttagtca
     5041 tgagttagta gctaaaatag tcagcatata gggaaactta tatgtagaga taggatagaa
     5101 cctatccaat actacttgaa ttgctaaaaa cccctaaagc taaccaaact aaaacataag
     5161 gatgaaataa acctaagtgt gaaagttacg aaagtagaaa aaattggtta gatggtataa
     5221 ggttaaaccc taagtacttt aaaatgggca atcagcaggt aaactccaaa taggagaaac
     5281 ttcaacgact attcctcttg agggaagtac actacaagtt atcggtagtg gaagtgggta
     5341 gaccttagca gataatgccg aaggataaga tatagtctgt gcttatgtga aagtgtaaga
     5401 agttcataag agaactgcat aggtagtagc gaacttatgt gaacgacaac ctcaaaaatg
     5461 ataaaagtta agacttacgg ttcttatata tgttatttaa aattaaatat aaaaccttct
     5521 aaataattgt tttaaataat tacatttgtt aacattatta taggtgatta ataaattgtt
     5581 caccacagca ttatataata tattaaatat taaaatcatt aaaaagtgta tcaaaaaaca
     5641 attaaagtga ggtgatagca gtgaaaaaag cttataagtt tagaatatat cctaataaaa
     5701 aacagcaaga gttaattaac aaaacttttg gatgttgtag gtttgtatat aat
//
LOCUS       DAEPHU010000140         5718 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 01A10CD0081
            SAMN05941466-rid12468953.denovo.142, whole genome shotgun sequence.
ACCESSION   DAEPHU010000140 DAEPHU010000000
VERSION     DAEPHU010000140.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941466
            Sequence Read Archive: SRR6291087
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 5718)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5718)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068158.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 22:43:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,892
            CDSs (total)                      :: 3,805
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 87
            rRNAs                             :: 8, 1, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 55
            CDSs (without protein)            :: 55
            Pseudo Genes (ambiguous residues) :: 0 of 55
            Pseudo Genes (frameshifted)       :: 21 of 55
            Pseudo Genes (incomplete)         :: 28 of 55
            Pseudo Genes (internal stop)      :: 16 of 55
            Pseudo Genes (multiple problems)  :: 8 of 55
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5718
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941466-rid12468953.denovo.142"
                     /strain="01A10CD0081"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            complement(62..223)
                     /locus_tag="KR231_003650"
     CDS             complement(62..223)
                     /locus_tag="KR231_003650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0005975.1"
                     /translation="MDNFLLSILASLIASLIGYIVCRCIKNVKSHSTRGKSKSGWELG
                     FKIKFRKFK"
     gene            complement(544..984)
                     /locus_tag="KR231_003651"
     CDS             complement(544..984)
                     /locus_tag="KR231_003651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HBH0005976.1"
                     /translation="MGDLNAFLSQNAIKVENRKYVASERFIGEDGKAIEWELKAIDSD
                     RDRQLRKDSTIRVPVLNKKGKATGQYTSETDFNTYTLKLCVETVVFPDLHDAELQNSY
                     GVMGAEELLTTMLTPGEYTDLSSEVGEVNGFDRTFEDKVEEAKN"
     gene            complement(989..1246)
                     /locus_tag="KR231_003652"
     CDS             complement(989..1246)
                     /locus_tag="KR231_003652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0005977.1"
                     /translation="MIKIKDKYEIKDSISFDYSNKRPLEERVSEMYKKAGKYLIDISD
                     KLATDTIDGSSLKPIIIKFEINEAGVATIEKQTKYLVMEVE"
     gene            complement(1299..1769)
                     /locus_tag="KR231_003653"
     CDS             complement(1299..1769)
                     /locus_tag="KR231_003653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail tube protein"
                     /protein_id="HBH0005978.1"
                     /translation="MAQQIKARDTISASKAECFVTIKGKRYNFMQAINLEAKMEKNKS
                     EIPILGSTTKGNKSTGSKYSGNATFYYNTSIFRELLYEYKETGEDIYFDIQITNEDPT
                     SSVGRQTIILEDCNMDSGIIAKFDADGEYLDEDMDFTFENWKLVEKFNIANGME"
     gene            complement(1791..3101)
                     /locus_tag="KR231_003654"
     CDS             complement(1791..3101)
                     /locus_tag="KR231_003654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail sheath family protein"
                     /protein_id="HBH0005979.1"
                     /translation="MALGGGTFVTQNKVLPGSYINFVSATRATSSLSDRGIVAMPLEL
                     DWGIDEEVFQVTSDDFEKYSTKYFGYDYTHEKLKGLRDLFKNIRLGYFYKLNKGVKAS
                     CSIATARCSGIRGNDLKVIVTTNIDDNAKFDVVTLLDNKKVDTQIAKVITELQDNDYV
                     TWKKEATLEATAGLTFTNGTNGEAVTGTEYQAFLDKIESYSFNALGCLATTAEIKSLF
                     VEFTKRMRDKVGAKFQTVLYKKNDADYEGVVSVENKIKDTGLLESSLIYWTTGAIAGC
                     DINKSNTNKRYDGEFDVDVNYTQIHLEEALKTGKFIFHKVGDEVHVLEDINTFVSFTD
                     EKNDDFSSNQSVRVLDQIANDIATLFNTKYLGEVPNDKSGRISFWNDVVKHHEQLQNM
                     RAIEDFKADDVSVEPGSDKKTVVVSDAVKVISAMSKLYMTVSVS"
     gene            complement(3102..3278)
                     /locus_tag="KR231_003655"
     CDS             complement(3102..3278)
                     /locus_tag="KR231_003655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0005980.1"
                     /translation="MSKTLSKGTDYKFTKEQIVNSKKYVNRKDLLNAILKENELYSFS
                     EVEDRINKFMKGVS"
     gene            complement(3271..3708)
                     /locus_tag="KR231_003656"
     CDS             complement(3271..3708)
                     /locus_tag="KR231_003656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0005981.1"
                     /translation="MLNNIIDGISVKLDKSFGEKYTIYSEDVEQGINEPCFFIVPLNP
                     SKTPYPSGRELKKNSFDVHYFPRSEAKNFEINEIAEMLLEELEYIEINGDLVRGTNMN
                     FEIIDNVLHFFVDYNYFTIKSNNADKMNTVELFGGLKRGDNFE"
     gene            complement(3701..4126)
                     /locus_tag="KR231_003657"
     CDS             complement(3701..4126)
                     /locus_tag="KR231_003657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HK97 gp10 family phage protein"
                     /protein_id="HBH0005982.1"
                     /translation="MARWGSVDFREFKRVCKKMEKLTKIDLDKFCKDAARELAARLLG
                     KVIRRTPVDTGFLRQGWNGVAYARSLPVYKQGNNYIIEVVNPTEYASYVNFGHRTKDG
                     KGWVKGQHFLTISEMELQSQVDKIIEKKLLILLKGVFDA"
     gene            complement(4126..4473)
                     /locus_tag="KR231_003658"
     CDS             complement(4126..4473)
                     /locus_tag="KR231_003658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015984843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0005983.1"
                     /translation="MVSKTRKAIEMLYRYKCTIVEYQPIKDPVTKRTNNKEVIVLENQ
                     PCKLSYKNIVSATEGKLAKLEQTIKLFISPDIEIKAGSKLIINDKEYVRSGESAIYPN
                     HQEIILELFKDKA"
     gene            complement(4467..4868)
                     /locus_tag="KR231_003659"
     CDS             complement(4467..4868)
                     /locus_tag="KR231_003659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0005984.1"
                     /translation="MGNNIIDDIEKRLESFGYILKDGDKWLIDFVREKIENIIKLDCN
                     IKTMPIELKEIEADMIVGEFLFTKKNMGQLDIESINFEAVEKSISEGDTKVDFAIGSG
                     SQTPEQRFDSLIAYLTAYGKNKILTFRCLRW"
     gene            complement(4878..5111)
                     /locus_tag="KR231_003660"
     CDS             complement(4878..5111)
                     /locus_tag="KR231_003660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0005985.1"
                     /translation="MAQVRKLNRILTIEECKIDDFLEMGYDLIDETGKVVRYGKSLNV
                     KDLIAENNILRSKVESLEEENKQLKEKNKLTKK"
     gene            complement(5111..>5718)
                     /locus_tag="KR231_003661"
     CDS             complement(5111..>5718)
                     /locus_tag="KR231_003661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861029.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="capsid protein"
                     /protein_id="HBH0005986.1"
                     /translation="VASIGNITKVYNEEQKFPEMDAYCISKIYADWTALGNTADTTVL
                     TTTNVLEVFDKLMEKMTEARVPENGRILYVTPVVNTLIKNAKEIQRTVNIKDAGTSLN
                     RQTTDIDTVKIIKVPSNLMKTAYDFTTGWKVGAGAKQIFMSLVHPSAIITPVSYQFSK
                     LDEPTAVTEGKYFYFEESFEDVFILNKKADAIQFVVEGAGA"
BASE COUNT         1683 a         1148 c          601 g         2286 t
ORIGIN      
        1 gcaagaagaa ctacaatcta tttagcggta gagtgaagtt cataatttta aaaaatataa
       61 attatttaaa tttgcggaac tttattttaa aaccaagttc ccagccactt ttactcttgc
      121 cacgagtaga gtggcttttt acgtttttga tacatctaca aacgatatat ccaattaaac
      181 tagctatcaa gctagctaat atactaagta aaaaattgtc catacttccc acctcctttc
      241 attaggaagt aggttttatc ccagtatgaa ctccactcta taaattgtag attacatctt
      301 cttgctacaa ttattataac atataattct tacatatttt acctatattt tatcttcttc
      361 tacttcttct agcttcttta gcaatctttt tttcttcttt tatttcttct tctactttaa
      421 tatctataga agcagcaaca aatgccctct cgaagtctgg taaatctgta tattcatgtg
      481 gtttccattt gaatttatga aggcaataat gagctacact agcatcataa tcgcctcctt
      541 caattagttt tttgcttctt ctactttatc ttcaaaagtc ctatcaaaac cattcacttc
      601 tcctacctca cttgaaaggt ctgtgtattc accaggagtt aacattgttg ttaatagttc
      661 ctctgctccc attacaccat agctattttg aagttctgca tcatgtaaat ctggaaatac
      721 tacagtttct acacacagtt tcaaagtata agtattaaaa tctgtttcac tagtgtattg
      781 ccctgttgct ttcccttttt tatttagtac aggtactctt atagttgaat cttttcttaa
      841 ttgtctatct ctatctgaat ctattgcttt aagttcccat tcgattgctt ttccatcttc
      901 tcctataaac ctttcacttg ccacatactt tctattctct acttttattg cattttgact
      961 taaaaaagcg tttaaatctc ccatattctt attctacctc catcaccaaa tattttgttt
     1021 gtttttctat tgttgcaaca ccagcttcat ttatttcaaa ttttatgatt attggcttta
     1081 atgacgaacc atcaattgta tctgttgcta acttatctga aatatctata agatattttc
     1141 ctgccttttt atacatctcg ctgacacgtt cttccaaagg tcttttattg ctataatcaa
     1201 aagaaattga atcttttatc tcatatttat ccttaatttt aatcatctcc tattcttata
     1261 aataaaaaat acacatacat aaatcataaa tgtgtatttt actccatacc atttgctata
     1321 ttaaatttct caactaattt ccaattctca aaagtaaaat ccatatcttc atctaaatac
     1381 tccccatcag catcaaattt agcaattatg cctgagtcca tattgcaatc ttccagtatt
     1441 atagtttgac gacccactga acttgttggg tcttcattgg taatttgtat atcgaagtaa
     1501 atatcctcac cagtttcttt atactcatac aacaattctc taaatataga ggtattataa
     1561 taaaatgttg catttcctga atatttactt cctgttgatt tatttccttt tgtagtacta
     1621 cctaatatag gtatctcact cttattcttt tccattttag cttctaagtt aatagcttgc
     1681 ataaaattat atcttttacc ttttatagtt acaaaacact ctgccttaga tgcacttatt
     1741 gtatctcttg cttttatttg ttgtgccatt attattctcc tttcttattg ttaactaact
     1801 gaaacagtca tataaagctt actcatagca ctaataactt ttacagcatc acttactaca
     1861 acagtcttct tgtcgcttcc aggttctaca gaaacatcat cagctttgaa atcttctatt
     1921 gctctcatat tttgcagttg ttcatgatgc ttaactacat cattccaaaa cgagatacga
     1981 ccagatttat catttggtac ttcacccaag tactttgtat taaataaagt cgctatatca
     2041 ttagcaatct ggtcaagtac tctaacactt tgattacttg aaaagtcgtc attcttttca
     2101 tctgtaaaac taacaaaagt atttatatcc tctaatacat gaacttcatc tccaacctta
     2161 tgaaatataa acttaccagt ttttaaagct tcttctaaat gtatttgagt gtaattaaca
     2221 tctacatcaa attcaccatc atatcgcttg ttagtattag atttatttat atcgcatcct
     2281 gctatagctc cagtagtcca gtaaattaag ctagattcta ataatccagt atctttaatc
     2341 ttattttcaa cagatactac accttcataa tctgcatcat tctttttata taatacagtt
     2401 tgaaacttag ccccaacttt gtctctcatt ctcttagtaa actctacaaa caaactttta
     2461 atctctgctg ttgtagccaa acatcctagt gcattaaatg agtaactttc tatcttatca
     2521 agaaaagctt gatactctgt tcctgtcaca gcttcaccat tagttccatt agtaaaagtt
     2581 aatcctgctg tagcctctaa tgttgcttcc ttcttccaag tgacataatc attatcttgc
     2641 agttctgtaa taactttagc tatttgagta tcaactttct tattatctaa aagtgttaca
     2701 acatcaaatt tagcattatc atctatattt gttgttacta taacttttaa gtcattacct
     2761 cttataccac tgcatctagc tgtagcaata ctacaactag ctttaacacc tttatttaat
     2821 ttatagaaat atcctagcct tatattttta aataaatctc tcaaaccttt caacttctca
     2881 tgtgtataat catatccaaa atacttagtt gaatacttct caaaatcatc actagtcact
     2941 tgaaatactt cttcatcaat tccccaatca agttctaaag gcattgcaac aatacctcta
     3001 tcgctaagtg aactggttgc ccttgtggca cttacaaagt ttatatagct acctggtaat
     3061 actttattct gtgttacaaa tgttcctcca cctaaagcca tctaactcac tcctttcatg
     3121 aatttattta ttctatcctc tacttctgag aaggaatata actcattttc ttttaaaatt
     3181 gcatttaata agtcttttct atttacatac ttcttagaat taactatctg ctccttagta
     3241 aacttgtaat cggttccttt gcttaatgtc ttactcaaaa ttatcacctc tcttcaaacc
     3301 accgaataac tctactgtat tcattttatc tgcattatta ctctttatag tgaagtagtt
     3361 ataatcaaca aagaagtgaa gaacattgtc tataatttca aaattcatat ttgtgcctct
     3421 aactaaatct ccattgattt ctatatactc taattcttcc agtaacatct cagctatctc
     3481 atttatttca aaattcttag cttctgaacg agggaaataa tgtacatcaa aagaattttt
     3541 ctttaattct ctcccgcttg gatatggtgt cttgcttgga tttaaaggaa caataaaaaa
     3601 acaaggttca ttaatacctt gctctacatc ctcactataa attgtatatt tttctccaaa
     3661 tgatttatct aactttactg atattccatc tataatatta ttaagcatca aatactcctt
     3721 taagtaatat taataacttt ttctctataa tcttatcaac ttggctttgt agttccatct
     3781 ctgaaattgt taagaaatgt tgtcctttaa cccaaccttt tccgtcttta gttctatgcc
     3841 cgaaatttac ataacttgca tattcagtcg gattaacaac ctctataata taattatttc
     3901 cttgtttata cacaggaagc gacctagcat aagccactcc attccatcct tgtcttaaga
     3961 atcctgtatc aactggtgtc cttctaatta cttttcctaa gagtcttgct gctaattctc
     4021 ttgctgcatc tttgcaaaac ttatctaaat caatctttgt aagcttctcc atctttttac
     4081 aaactctttt aaactctcta aaatcaacac tgccccatct agccattatg ctttatcctt
     4141 aaataactca agtattattt cttgatgatt tggatatata gctgattctc cacttcttac
     4201 atactcttta tcatttataa taagttttga acctgcttta atttctatat ctggagatat
     4261 aaagagttta atagtttgct ctagcttagc taattttcct tctgtagcag aaactatatt
     4321 tttatatgaa agcttgcatg gttgattttc taatacaatc acttctttat tgttagttcg
     4381 ttttgttaca gggtctttga ttggctgata ctcaactata gtacatttat atctatataa
     4441 catttctatt gcttttctag ttttacttac catcttaagc acctaaaggt taatatctta
     4501 ttcttaccat aagcagtaag ataagctatt aagctatcaa agcgttgttc tggtgtttga
     4561 gagccacttc ctatagcgaa atctaccttt gtatcacctt ctgatataga cttttctaca
     4621 gcttcaaagt taatgctttc tatatctaat tgccccatat ttttcttggt aaataagaac
     4681 tctccaacta tcatatcagc ttcaatttct ttcaattcaa ttggcatagt ttttatatta
     4741 caatctagtt taataatatt ttctattttt tctcttacaa aatctattaa ccacttatcc
     4801 ccatctttta atatatatcc aaaactttca agtctttttt ctatatcatc aattatatta
     4861 tttcccataa ttttcaccta ctttttagta agtttatttt tctctttaag ctgcttattt
     4921 tcttcttcta aagactcaac ttttgacctt aaaatattat tttcagctat taaatctttt
     4981 acatttaatg acttgccata ccttactacc ttaccagttt catctatcaa atcatatccc
     5041 atctctaaga aatcatctat tttacactct tctatggtta atattctatt taatttcctt
     5101 acttgtgcca ttatgctcca gctccttcaa caacaaattg tattgcatca gcttttttat
     5161 ttaatataaa tacatcctca aaactttctt caaagtagaa gtattttccc tctgtaactg
     5221 ctgttggttc gtctaactta gagaactgat aagaaacagg tgtaattatt gcacttgggt
     5281 gaactaagga cataaagatt tgtttagctc ctgctcctac tttccatcca gttgtaaaat
     5341 catatgcagt tttcattaga ttagatggta ctttaattat tttaactgtg tcaatatcag
     5401 ttgtttgacg attaagagaa gttcctgcat cctttatatt tactgttctt tgtatctctt
     5461 ttgcattttt gataagtgta tttactactg gagtaacata caatattctt ccattttcag
     5521 gtactctagc ttctgtcatt ttttccatta acttatcaaa tacttctaat acgtttgttg
     5581 ttgtaagaac agttgtatct gctgtattac ctaatgcggt ccaatcagca tatattttag
     5641 atatacagta agcatccatc tctggaaact tttgttcctc attatatact tttgttatat
     5701 tgcctattga agccacat
//
LOCUS       DAEPHU010000141         5711 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 01A10CD0081
            SAMN05941466-rid12468953.denovo.143, whole genome shotgun sequence.
ACCESSION   DAEPHU010000141 DAEPHU010000000
VERSION     DAEPHU010000141.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941466
            Sequence Read Archive: SRR6291087
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 5711)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5711)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068158.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 22:43:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,892
            CDSs (total)                      :: 3,805
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 87
            rRNAs                             :: 8, 1, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 55
            CDSs (without protein)            :: 55
            Pseudo Genes (ambiguous residues) :: 0 of 55
            Pseudo Genes (frameshifted)       :: 21 of 55
            Pseudo Genes (incomplete)         :: 28 of 55
            Pseudo Genes (internal stop)      :: 16 of 55
            Pseudo Genes (multiple problems)  :: 8 of 55
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5711
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941466-rid12468953.denovo.143"
                     /strain="01A10CD0081"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            183..440
                     /locus_tag="KR231_003662"
     CDS             183..440
                     /locus_tag="KR231_003662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0005987.1"
                     /translation="MIIIRSQDKTNLMQINQIKIDGSQVYAVFESKIDTVKIGDYENN
                     TRAIQVLDNIQNFIENGTKYDYITSNKVRYNVNKIFQMPAK"
     gene            complement(550..1230)
                     /locus_tag="KR231_003663"
     CDS             complement(550..1230)
                     /locus_tag="KR231_003663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HBH0005988.1"
                     /translation="MIWTFYSFICVILPCLIYQIVVIKRKNLKVEKNVMIHLVWVYIF
                     LLYIYLALSKAGIGSIWDIGRYSGLFRIDEINLIPFDSVGILTYILNIIMFMPLGFLL
                     PLIWKNFRNIINVSLTGLGFSLAIELCQLFNLRATDIDDLMMNTLGAVLGYFIWVGVN
                     NLFNLIKKKDIFPSIYKNIIQDEIAITIDDDISEKITSLYKNEAIIYLILAVLGEFLL
                     FNWSIIPY"
     gene            1490..1789
                     /locus_tag="KR231_003664"
     CDS             1490..1789
                     /locus_tag="KR231_003664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0005989.1"
                     /translation="MKWIKWYSITCICIFIVVAFYMFIFPNKIETIDTSSAYSFVEKK
                     VPNSAVYQGYKKNPVDGTTTIYYSYDNSTHIVRLSHPEDYSRKINWDKVSNIRFD"
     gene            2113..3768
                     /gene="ilvD"
                     /locus_tag="KR231_003665"
     CDS             2113..3768
                     /gene="ilvD"
                     /locus_tag="KR231_003665"
                     /EC_number="4.2.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020457899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxy-acid dehydratase"
                     /protein_id="HBH0005990.1"
                     /translation="MRSDIKKGIEGAPKRALMYGMGLTKEEIERPLIGIVNAQNEVIP
                     GHLHLDEIAEAAKNGVRMSGGLPLEFPAIGVCDGIAMGHVGMNYSLASRELIADSIEA
                     MAMAHGFDALVLIPNCDKIVPGMLMAAARLNIPSIVVSGGPMLPGKKNGKVYDFNSAM
                     EGVGACKDGTVSEEELEALAMNSCPGCGSCSGLFTANSMNCLTEALGMGIPYNGTAAS
                     HSGERKRIAKYAGMYVMELLKNDIKPRDILTIDAFKNAIAVDMAMAGSTNTVLHLPAI
                     AYESGIELNLNFFDEISEKTPCLTKLSPSGKHHIEDLHMAGGIPAIMNELSKINGINL
                     DCKTVTGKTIGENIRNCEIENEEVIHTLKNPYSNQGGLAILKGNLALNGAVVKKSAVA
                     EEMLVHEGPARVFNSEEEAVNAIFGKKINKGDVIVIRYEGPKGGPGMKEMLSPTSAVA
                     GMGLDKHVALLTDGRFSGATRGASIGHISPEAMEGGLIGLVEEGDIISINIPDKKLEL
                     KVDEVEIENRKLKFKPLEPKIKHGYLSRYAKLVTSANTGAVLK"
     gene            4112..4744
                     /locus_tag="KR231_003666"
     CDS             4112..4744
                     /locus_tag="KR231_003666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBH0005991.1"
                     /translation="MNREEKSKNSKEKIIQSAFSLFSSKGYDSTSTQDIINLSGLSRG
                     AMYHHFKTKEDILRSVTKELYSQMNNFLEHLVADDTLTANEKIIELVVHSANDYTRRK
                     MVHCSWLEKIPFALIEEVRNLNNVVAPNIAKIIKQGVENKEFSCEYPEELAEMLVFSI
                     DILLDPVLFKREYSEVCNRLDFLLFMLKKMDIPLIDEYGIQKFKDLFRQL"
     gene            4767..5579
                     /locus_tag="KR231_003667"
     CDS             4767..5579
                     /locus_tag="KR231_003667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HBH0005992.1"
                     /translation="MFYNAKSCQMMIGSNTVNYIEFGSGKKTLIILPGLGDGLFPLHG
                     KIQAIAFAFRYKQFAKDYKVYVFSRKNQITEKYSTRDMAKDQADIMKKLGIMKAEVMG
                     VSQGGMIAQYLAIDYPELVEKLVLAVTSSKQNDTIQNVICSWIDMAKKQNYNDLMIDT
                     AKKSYSERYLKKYQLFIPFLGKVGKPKDFKRFIIQATSCIEHNAFSELNKITCPTLII
                     GGANDKIVGNNASFHLAEKIKKSEIFIYEGLGHATYEEAQDFNERVLEFLNK"
BASE COUNT         2265 a          643 c          938 g         1865 t
ORIGIN      
        1 ataaaacaaa gtattatcaa aaaagtattc tttaagaaaa ttttttatta gagatgtaat
       61 tgatataaat aatcgtatta aaaaataaaa tactaagttt aaaaatttaa ataatctata
      121 aatcaattat aaaatattat ttcttagaaa ttaaaatgaa ttaagtaaat ggaggaattg
      181 atatgataat aattagaagt caagataaaa ctaatttaat gcagataaac caaattaaaa
      241 tagatggtag tcaagtttat gcagtatttg aaagtaaaat tgatactgta aaaataggag
      301 attatgaaaa taatacaaga gctatacaag tgttggacaa tatacaaaac ttcattgaaa
      361 atggaacaaa atatgattat ataacatcaa ataaagtcag atacaatgtt aataaaatat
      421 ttcagatgcc agctaaatag tgagtgtgca ttttaattta ataactaaag cccactttct
      481 tttgtggtat gaaagagggc tttacatatt tgtaaatatc gaagtacact tgttttatca
      541 ataaattatt taataaggta taatggacca attaaacaat aaaaattctc ctaaaacagc
      601 aagtattaaa tatataatag cttcattttt gtaaagagag gtaatttttt cgcttatgtc
      661 atcatcaatt gtaatagcaa tttcatcttg aataatattt ttatatatag atgggaaaat
      721 atcttttttc tttataagat taaataaatt atttacacct acccatataa aatatcctaa
      781 aacagcacct aatgtgttca tcattaaatc atcaatatct gtagctctta agttaaacaa
      841 ttgacaaagt tcaattgcta atgaaaaacc taatccagtt aatgaaacat tgataatatt
      901 tctaaaattt ttccaaatta aaggtagtaa aaatcctaaa ggcataaaca taattatatt
      961 taaaatatat gttaagatgc caactgagtc aaaaggtatt agatttattt catcaattct
     1021 aaaaagccca ctataccttc ctatatccca tatgctacca attccagctt tactaagtgc
     1081 tagatagata tataataaaa aaatatatac ccatactaaa tgtatcatta cattcttttc
     1141 aactttcaaa ttttttcgtt ttataacgac tatttggtat attaagcatg gtaatataac
     1201 gcaaataaat gaataaaatg tccatatcat tttattttgt cccctttcaa atttatgttt
     1261 ttagttttat aagtactatc tttatattaa actgtaagtt ttaaaaatct tttaataaaa
     1321 tcttaaaaat ttattaattt ataaaaatat attattaaga ttaaaaaata tatataatca
     1381 aagtttctac aattatatag ttagggatat aaaaatttta tcgtatgcat aaatattata
     1441 aatatatgga aataataata gtatattttg gtaaagtagg aggaatttta tgaaatggat
     1501 taaatggtat agtattacat gcatatgtat ttttatagta gtagcttttt atatgtttat
     1561 atttcctaat aaaatagaaa ctattgatac ttcatctgca tatagctttg ttgaaaagaa
     1621 agtaccaaat agtgctgtgt atcaaggata caaaaagaat ccagttgatg gtactactac
     1681 aatttattac agctatgata attcaactca tatagttaga ttatcacatc cagaagacta
     1741 ttcaaggaag attaattggg ataaagtttc aaacatcaga tttgattaat ctttaatatt
     1801 tataaaagtc tatatatcta aggcaaatat attattaatc ttattcatag ttgagcactt
     1861 tctattatag aagtgcctct tctgatttat atcataaaat attactcaac aatttgtaaa
     1921 atatattagt ttataaaata tattgaaaag ataatattat ataatacaat tgtgtaagat
     1981 attgataaaa aatcgtaata aattttcatt agtatatgct aatatttttt tacaattttc
     2041 gtaattaatt aatagaaaaa tatattataa taatattatg aaaatttaaa aaagtaagaa
     2101 agaggtaata ttatgagaag tgatataaaa aaaggaatag aaggagctcc aaagagagcg
     2161 ttaatgtatg gaatgggtct tactaaagaa gaaattgaaa gaccattaat aggtatagta
     2221 aatgcacaaa atgaggtgat tcctggtcat ctgcatcttg atgaaatagc agaagctgca
     2281 aaaaatggag taagaatgag tggtggtttg ccattagaat ttcctgctat aggggtatgt
     2341 gatggtatag ctatggggca tgttggaatg aattattccc tggcttcaag agaattaata
     2401 gcagattcaa tagaagctat ggctatggca catggttttg atgctttggt acttatacct
     2461 aattgtgaca agatagtgcc aggtatgtta atggctgctg caagacttaa tataccaagt
     2521 attgttgtga gtggagggcc tatgcttcca ggtaaaaaaa atggaaaagt atatgatttt
     2581 aactctgcaa tggagggtgt tggagcatgt aaagatggaa cagtaagtga agaagaatta
     2641 gaagcgttag ccatgaactc ttgtcctgga tgtggttcat gttctggtct tttcacagca
     2701 aatagcatga attgtttaac agaagcttta ggcatgggta taccatataa tggtactgct
     2761 gcgtcacatt ctggagaaag aaaaaggata gcaaaatatg caggtatgta tgttatggag
     2821 ttacttaaga acgacataaa acctagagat attttaacaa tagatgcttt taaaaatgct
     2881 atagctgtgg atatggcaat ggctggttct acaaatacag tacttcactt acctgcaata
     2941 gcttatgaat caggaataga gcttaactta aatttttttg atgaaataag tgaaaaaact
     3001 ccttgtttaa caaaattaag tccaagtgga aaacatcata ttgaagattt acatatggca
     3061 ggaggaatac cagctataat gaacgaactt tcaaagataa atggaataaa tttagattgc
     3121 aaaaccgtaa caggcaagac tataggggaa aatataagaa attgtgaaat agaaaatgaa
     3181 gaagtaatac atacattaaa gaatccatat agtaaccaag gtgggcttgc aatattgaaa
     3241 ggaaatcttg ctctaaatgg agctgttgta aaaaagtcag cagttgcaga agaaatgtta
     3301 gttcatgaag gaccagcaag agtttttaat tcagaagaag aagctgtaaa tgctattttt
     3361 ggtaaaaaaa taaacaaagg tgatgttata gttataagat atgaaggtcc aaagggtggt
     3421 ccaggaatga aagaaatgct atctcctaca tcagcagttg caggaatggg acttgataag
     3481 catgtagcac ttcttactga tggtcgtttt tcaggagcaa ctagaggagc atctataggc
     3541 catatttctc cagaagctat ggaaggtggt ttaatcgggt tagttgaaga aggagatata
     3601 atttctataa acataccaga caaaaaatta gagttaaaag tagatgaagt tgaaatagaa
     3661 aatagaaaat taaaatttaa acctttagaa ccgaaaataa agcatggata cttaagtaga
     3721 tatgctaaac tggtaacatc agcaaataca ggagcagttt taaaatagta gactatattt
     3781 atgtaaatta gaaaaagtta agaaaatatt aattggatat cttaggtgtt atagcactaa
     3841 tgaggtatcc tttttatttt gtatgaaaaa cacagcaaaa tcttgattat ctttgaaaac
     3901 aatacatctc tattataagg aatacgagta cagcatagag atgtatcttt tagaccttgt
     3961 tgaggtaata caacttttta aaagtttgat gtggaatgct tttcgttcca tctgaactat
     4021 gaagaaattg aaagtcagtt aattcttgac ataataaata ttaaaatgta taataaaaaa
     4081 caaacagaca gtctgttttt aggagggaaa tatgaataga gaagaaaaaa gtaaaaatag
     4141 taaagaaaaa attatccaat cagcattttc actattttcg tctaaaggat atgattcaac
     4201 atctacacaa gatattatca atttatctgg tctatctaga ggtgcaatgt atcatcactt
     4261 taaaactaaa gaagatatac tgagaagtgt cacaaaagaa ctttactcac aaatgaataa
     4321 ttttttagag catcttgttg ctgatgacac ccttacagca aatgaaaaaa taatagaatt
     4381 ggttgttcat agtgcgaatg attacacacg tagaaaaatg gtacattgta gctggttaga
     4441 aaaaatccca ttcgctttaa tagaggaagt tcgtaatctc aacaatgtag ttgcacccaa
     4501 tattgctaag ataattaaac aaggtgttga aaataaagaa ttttcttgtg aatatccaga
     4561 ggaattagct gaaatgctcg tttttagtat tgatatttta cttgaccctg tattatttaa
     4621 acgtgaatac agtgaagtat gtaataggtt ggatttttta ttattcatgt taaaaaaaat
     4681 ggatattcct ctaattgatg agtatggtat tcaaaaattt aaagatttat ttagacaatt
     4741 ataataggaa aagcgaggaa tagactatgt tttataatgc aaaaagttgt caaatgatga
     4801 taggaagtaa tacagtgaat tatattgaat ttggtagtgg taagaagaca ctaattattt
     4861 taccaggatt aggagatggt ttatttcctt tacatggaaa aatacaggcg attgcttttg
     4921 cttttagata taagcaattt gcaaaagatt ataaggttta tgtatttagt agaaaaaatc
     4981 aaattacaga aaaatattcc acaagggata tggctaaaga ccaagcagat ataatgaaaa
     5041 aacttggaat tatgaaagca gaagtaatgg gtgtttctca aggtggaatg atagctcaat
     5101 atctggcaat tgattatcct gagttagttg agaaacttgt gttggcagtt acttcttcaa
     5161 agcaaaatga tactatccaa aatgttattt gtagttggat tgatatggcg aagaagcaga
     5221 attacaatga tttaatgatt gacacagcaa agaaatccta ttctgaaaga tatttaaaaa
     5281 aataccaatt atttattcct tttttaggaa aagtaggtaa accaaaggat tttaaacgat
     5341 ttattattca agcgacctct tgcatagaac ataatgcctt ttccgaatta aataaaataa
     5401 catgtccaac cttaattata ggaggtgcta atgataaaat tgttggaaat aatgcttctt
     5461 ttcatttagc agaaaagatt aaaaaaagcg aaatatttat ctatgaggga ttgggacacg
     5521 ctacatatga agaagcacag gattttaatg aaagagtttt agagttttta aataagtaaa
     5581 cacctttgtt aaaaatatac atatgaagat tggaaattta atgttaaaaa tagaaacatg
     5641 aaaatatgct taactggtat ttttactatt cataaccaat ttttgataca ttatctacta
     5701 taaatacaaa t
//
LOCUS       DAEPHU010000142         5672 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 01A10CD0081
            SAMN05941466-rid12468953.denovo.144, whole genome shotgun sequence.
ACCESSION   DAEPHU010000142 DAEPHU010000000
VERSION     DAEPHU010000142.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941466
            Sequence Read Archive: SRR6291087
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 5672)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5672)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068158.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 22:43:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,892
            CDSs (total)                      :: 3,805
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 87
            rRNAs                             :: 8, 1, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 55
            CDSs (without protein)            :: 55
            Pseudo Genes (ambiguous residues) :: 0 of 55
            Pseudo Genes (frameshifted)       :: 21 of 55
            Pseudo Genes (incomplete)         :: 28 of 55
            Pseudo Genes (internal stop)      :: 16 of 55
            Pseudo Genes (multiple problems)  :: 8 of 55
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5672
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941466-rid12468953.denovo.144"
                     /strain="01A10CD0081"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            <1..1103
                     /locus_tag="KR231_003668"
     CDS             <1..1103
                     /locus_tag="KR231_003668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="Fic family protein"
                     /protein_id="HBH0005993.1"
                     /translation="YFTGNKIVLSINSFDNKELYYHETENILNLINEIDKLTSSKIFK
                     TIEDKNDLALESYYSSVIEGAFSTRKIAKSIIRGKMKPSNKSEYMIYNNHRALEYGLD
                     NLDKLYSHKFIYDLHHILGENCLDSEEYEYRTEKVYVCDSKGEIIHTGLEPLKIYDFM
                     SKLIDFMENSKVSNLIKSAIIHFYFVYVHPFSDGNGRTSRALSYLYLIDKGYDTFKDF
                     SISYMISKNRTKYYKAILDVENKGNNLTVFIEFMLKSIIQSINEMRNMHDRKSLESIL
                     KEELFENDITLSATEEHILKYICNKDNYSMTLENYIKKNKSRYLKAGIKEIELVDQLM
                     EVFNNLEEIEILSKEKNIYKVNDKYLKMLDID"
     gene            1129..1317
                     /locus_tag="KR231_003669"
     CDS             1129..1317
                     /locus_tag="KR231_003669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0005994.1"
                     /translation="MNNKKKAFLISGAINVISLIIVFSLFHYNIIENSTQNMIITVIL
                     IFIFEMIKIKIIEKYYKL"
     gene            2101..3651
                     /locus_tag="KR231_003670"
                     /pseudo
     CDS             2101..3651
                     /locus_tag="KR231_003670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901970.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein CwpV"
BASE COUNT         2557 a          640 c         1038 g         1437 t
ORIGIN      
        1 aatactttac tggaaataaa atcgtacttt ctataaatag ttttgataat aaagaactat
       61 actatcatga aactgaaaat atattaaatt taataaatga aatagataaa ttaacatcaa
      121 gtaagatatt taaaacaata gaagataaaa atgatttggc actagagtct tattattcta
      181 gtgtaataga aggtgctttt tcaactagaa agattgcaaa atctataatt agaggaaaga
      241 tgaaaccaag taataaaagt gaatatatga tttacaataa tcatagagcc ttagaatatg
      301 gattagacaa cttagataaa ttatatagtc acaaatttat atatgatttg catcatatat
      361 tgggcgaaaa ctgcttggat tcagaagaat atgagtatag aactgaaaaa gtatatgtat
      421 gtgattcaaa aggtgagatt atacatacag ggcttgaacc tttgaagata tatgacttta
      481 tgagtaaatt aatagatttt atggaaaata gcaaagtaag taatttaatt aaaagtgcta
      541 taattcattt ttactttgta tatgttcatc cttttagtga tggtaatgga agaacatcaa
      601 gagccttatc atatctatat ttgattgata aaggatatga tactttcaag gatttttcaa
      661 tatcatatat gatatctaaa aacagaacta agtattataa ggctatactt gatgtagaaa
      721 acaaaggaaa taatttaact gtatttatag aatttatgct caagtctata atacaatcta
      781 ttaatgagat gcgtaatatg catgatagaa aatctttaga aagtatatta aaagaagaat
      841 tgtttgaaaa tgacataact ctatcagcaa cagaagaaca tatattaaaa tatatttgca
      901 ataaagataa ctattctatg acattagaaa attatataaa aaagaataaa agtagatact
      961 taaaggctgg aataaaggaa attgaattag ttgaccagtt gatggaagtg tttaataatc
     1021 ttgaagagat agagattttg tctaaagaaa aaaatatata taaagttaat gataagtact
     1081 taaaaatgct tgatatagac taatttagat aatctggaga gggaatatat gaataataag
     1141 aaaaaggcat ttttgatttc tggggctata aacgtaattt cattaattat tgttttttca
     1201 ttgtttcatt ataatattat agaaaatagt acacaaaata tgataataac tgtaatctta
     1261 atttttattt ttgaaatgat aaaaataaaa atcatagaga aatactataa actataaaca
     1321 agaaatatct tttctaagag catattgtac aatatgctct taatttagtt atatagattt
     1381 aatataaata atgtattttt tgtagatgat ttatgtaaga tttatgacca atttgtgtat
     1441 gatttgtgtt ctttaatcat gacaatatta tattgtaaaa aataaattta ataaaaaatg
     1501 acttggaatt tatattctag gtctttttta tataaaaatt taataagttt caaatgttgg
     1561 taactttgac agtagaaaac gtctattgag ataacgagga ttctaattga gggggagaga
     1621 tattagcact taaagtagta tatgcaacag atataatctt tacaaaagta atttgaatta
     1681 aaatgtaaat ataaagaata attaaaaaaa tatcgcaatt atttgttttt catatggata
     1741 aaattggtta tttaatatat aattacaagt ataaataata aaatttattt gtaaaaagag
     1801 tagcactttt aattctaaag gctacttttt ttatacaaaa ccctattttt tataacaatt
     1861 cattaacata aaaatcaaac ttaccttaaa atataaattt acaaattttt caatcaataa
     1921 gaaaatttct ttattcctta cataatgact gcaatgtaac aaaataatta caaattaatt
     1981 atgaaatcat tatagttaga aacctcttta aaattagata ttaagtatcc tttagaatta
     2041 gaacgggaac aaagttaaaa aattaagtaa tatcaaatgg acaaggggga agaaaataaa
     2101 atgaaaatac caaagaagat tgctgcaatg cttacagtta caatgatagc tggaagttca
     2161 acagcaggca tagctagtgc acaaactgtg gcaacaaatt taacagggca agaaagatat
     2221 gaaactgctg ttaaaataag tcaagatgga tggaaaaatg ctgatgaggt agtaatcgta
     2281 aacgactcat ctatagcaga tgctctatct gcaacaccat ttgcaaaagc aaaaaatgct
     2341 ccaatacttt taacaagtaa agataaatta aatgataaga cgaaagcaga aatacaaaga
     2401 ttaaaagcta aaaaagtata cttaataggt ggaacttctg tattaagtac aaatatagaa
     2461 aaagaaataa aagatttaaa aatatctttt gagagaatct ctggagctga gagatatcaa
     2521 acatccttag aattagcaaa gaaattagat gctataagtg atgttaagaa aatagctgta
     2581 gttaatggtg aaaaaggact tgcagatgct gtaagtgtag gagcaccagc tgcacaaaac
     2641 aatatgccag taatacttgc tgattctaaa aatggaacag cagttgcaga caaatttata
     2701 aaagatgctg gaataactca atcttatgta gtaggtggag agagttcaat ttctgaagct
     2761 gttaaaaata aactaccaaa tagtacaaga ctaggtggaa cagatagaaa tgatacaaat
     2821 gcaaaagtaa taaaagaatt ttataaaaag acagatttaa aaaatgctta tgtaactaaa
     2881 gatggtatga ataaacaaga ccaacttata gatgcactag cagtaggtgt attaggtgct
     2941 aaaaatcaat caccagtagt tttagttgga aagaacttat cagcttcaca aaaatctcta
     3001 gttaactcta agagttttga taagataact aaagttggtg ggaatggtaa tgagacagca
     3061 tttaatgaaa tgaagtcatt acaagaagta aaaacagttg aagctaaaac aatttctgaa
     3121 ttaaaatcag ctatagataa agctactgct aatgatgtta taaactttaa gccaactagt
     3181 gaggttaaag aagcatttac aatacaaact gataaagcag taacagtaaa cttaaatggt
     3241 acatatacaa agactgtaac tatcaacatg cctaatggag atgtaaataa ctatgcaaaa
     3301 gtggatgatg tagttataga tgatgtaaaa gatggaactt ttgttaacta tggaaaaata
     3361 actaacttaa aggttaatga taaaaatgga gccaagatag aaaataattc taaaggtgag
     3421 attggtagtt taacagtagc atctggagca agtcaagtaa aagtgactaa tggtggtaag
     3481 ataactacag ttacaaataa ttctaaaggg actactatag ataataaagg tacaataagt
     3541 agtgttaagg gagataattc tccaacaata agtggaaata gtccaagttc taactcttca
     3601 ggaggaagtt catcaagtgg aggctcttca catggaggag gaagttcttc atcaaaacca
     3661 agcgataagt caaaaacaaa gacaaaagca gaagaaaaaa tagcagaggt aacaaaacta
     3721 gtaggaaaag taacagcaga taatttagaa gcatcaaaag taacattaaa agcagcaact
     3781 gatgcaatag aagaagcaag gaaagcaggg tggacagaat cagaagttca aagctttaaa
     3841 ggatatggag atatagcaaa agtacaaagt gagataactg aattagaatc acaggctaaa
     3901 gaagcagcaa agacaaaagc agaagaaaaa atagcagaag taacaaaact agtaggaaaa
     3961 gtaacagcag ataatttaga agcatcaaaa gtaacattaa aagcagcaac tgatgcaata
     4021 gaagaagcaa aggcagcagg atggacagaa tcagaagttc aaagttttgc aggatatgaa
     4081 gatatagcaa cagtacaagg tgagatagct gcattagaat catcacaggc taaagaagaa
     4141 gcaaagacaa aagcagaaga aaaaatagca gaagtaacaa aactagtagg aaaagtaaca
     4201 gcagaaaatt tagaagcatc aaaagtaaca ttaaaagcgg caactgatgc aatagaagaa
     4261 gcaaaggcag caggatggac agaatcagaa attcaaagtt ttgtaggata tgaagatata
     4321 gcaaaagtac aaagtgagat aactgaatta gaatcacagg ctaaagaagc agcaaagaca
     4381 aaagcagaag aaaaaatagc agaagtaaca aaactagtag gaaaagtaac agcagaaaat
     4441 ttagaagcat caaaagcaac attaaaagcg gcaactgatg caatagaaga agcaaaggca
     4501 gcagggtgga cagaatcaga agttcaaagt tttgcaggat atggagatat agcaaaagta
     4561 caaagtgaga taactgcatt agaatcatca caggctaaag aagaagcaaa gacaaaagca
     4621 gaagaaaaaa tagcagaagt aacaaaacta gtaggaaaag taacagcaga aaatttagaa
     4681 gcatcaaaag caacattaaa agtggcaact gatgcaatag aagaagcaaa ggcagcaggg
     4741 tggacagaat cagaagttca aagttttgca ggatatggag atatagcaaa agtacaaagt
     4801 gagataactg cattagaatc atcatcacaa gctaaagaag aagcaaagac aaaagcagaa
     4861 gaaaaaatag cagaagtaac aaaactagta ggaaaagtaa cagcagataa tttagaagca
     4921 tcaaaagcaa cattaaaagc ggcaactgat gcaatagaag aagcaaaggc agcagggtgg
     4981 acagaatcag aagttcaaag ttttgcagga tatggagata tagcaaaagt acaaagtgag
     5041 ataactgcat tagaatcatc atcacaagct aaagaagaag caaagacaaa agcagaagaa
     5101 aaaatagcag aagtaacaaa actagtagga aaagtaacag cagaaaattt agaagcatca
     5161 aaagcaacat taaaagcggc aactgatgca atagaagaag caaagacagc agggtggaca
     5221 gaatcagaag ttcaaagttt tgcaggatat ggagatatag caaaagtaca aggtgagata
     5281 actgcattag aatcatcatc acaagctaaa gaagaagcaa agacaaaagc agaagaaaaa
     5341 atagcagaag taacaaaact agtaggaaaa gtaacagcag ataatttaga agcatcaaaa
     5401 gcaacattaa aagcggcaac tgatgcaata gaagaagcaa agacagcagg gtggacagaa
     5461 tcagaagttc aaagttttgc aggatatgaa gatatagcaa aagtacaagg tgagataact
     5521 gcattagaat catcatcaca agctaaagaa gaagcaaaga caaaagcaga agaaaaaata
     5581 gcagaagtaa caaaactagt aggaaaagta acagcagata atttagaagc atcaaaagta
     5641 acattaaaag cagcaactga tgcaatagaa ga
//
LOCUS       DAEPHU010000143         5525 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 01A10CD0081
            SAMN05941466-rid12468953.denovo.145, whole genome shotgun sequence.
ACCESSION   DAEPHU010000143 DAEPHU010000000
VERSION     DAEPHU010000143.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941466
            Sequence Read Archive: SRR6291087
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 5525)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5525)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068158.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 22:43:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,892
            CDSs (total)                      :: 3,805
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 87
            rRNAs                             :: 8, 1, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 55
            CDSs (without protein)            :: 55
            Pseudo Genes (ambiguous residues) :: 0 of 55
            Pseudo Genes (frameshifted)       :: 21 of 55
            Pseudo Genes (incomplete)         :: 28 of 55
            Pseudo Genes (internal stop)      :: 16 of 55
            Pseudo Genes (multiple problems)  :: 8 of 55
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5525
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941466-rid12468953.denovo.145"
                     /strain="01A10CD0081"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            50..166
                     /gene="rrf"
                     /locus_tag="KR231_003671"
     rRNA            50..166
                     /gene="rrf"
                     /locus_tag="KR231_003671"
                     /product="5S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00001"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00001"
     gene            complement(380..1564)
                     /locus_tag="KR231_003672"
     CDS             complement(380..1564)
                     /locus_tag="KR231_003672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HBH0005995.1"
                     /translation="MLSKRLNFITPSYTIGISSKVKEMESNGVKVINLSIGEPDFNVP
                     NNAKSYGIDSLNKDYTKYDLVPGLKILREEICKKLIEENNCNYSIDEIVVSSGAKNSI
                     TNTLLALTDEGDEVLLPKPYWVSYPEMIKLVNAVPVFIDTKKENGFKLTKEELEKSIT
                     DKTKILVINNPSNPTGSVYTKDELIEIVDVCIQNKIYILADEIYEKICYTGEFTSIAS
                     LSEEAKDITITINGFSKSAAMTGLRLGYTASNKTIAKAMSSIQGHLISHPSLTAQYIA
                     YGALKDCSIDIDNMVKTYKSRRDLIKSKLDSIDNVGYVNPNGAFYIFIDLSKVSEKFE
                     YKDSFSIEFCNQFLEEYNVAVVPGIAFGMDKYIRISYACSENTFLSGLDKLKEFVYKI
                     MA"
     gene            1937..4288
                     /locus_tag="KR231_003673"
     CDS             1937..4288
                     /locus_tag="KR231_003673"
                     /EC_number="1.17.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside triphosphate reductase"
                     /protein_id="HBH0005996.1"
                     /translation="MVEFVKKRDGRVIPFNEDRITRAIFLAATNVAEREGIVPDYKLS
                     EQLTQEVIKFLNHKYSESVPSVEDIQDSVVKVLIETGHAKTSEEYIIYRTERSRIRNS
                     KTRLMKAIEEITFEDAEDADIKRENANINGNTAMGTMLQYGSTVSKEFCKTHILKPEH
                     SFAHDNGDIHIHDMDFLNMGTLTCCQIDVKKLFNGGFSTGHGFLREPQDIISYGALAA
                     IAIQSNQNDQHGGQSIPFFDYGLAEGVYKTFKKFYIGNLAKALKLFKGIENNDVIKNI
                     VYNTEKETNQKVGLKRDELYLNLEKEKLIQTFDIDDELVNKMQNFAFEESYRETDKKT
                     YQSMEAFIHNLNTMHSRAGAQVPFSSVNFGTDTSEEGRMVTKNLLLSQERGLGNGETP
                     IFPILIFKVKEGINLNPEDPNYDLFKLSCRVSAKRLFPNFSFLDAPFNAKYYKKGEPD
                     TEATYMGCRTRVLSNVCGSETVSGRGNISFTTVNLPRLGIKHGIINNEKANLDGFFEE
                     LDEKINLIIEQLLERLEVQGNKKMKNFPFLMGQGVWKGSDDLGPEDTLKEVIKQGTLT
                     IGFIGLAECLIALIGKHHGESKEAQELGLKIVSHMRHKMDEATDKYKLNFSLMGTPAE
                     GLSGRFTKIDKKVYGEIKGITDKEYYTNSFHVPVYYNISAYDKIEIEAPYHELTNAGH
                     ITYVELDGDPSDNLEAFETVIKAMKDLGIGYGSINHPVDRDPICGFSGVITSNICPVC
                     GRNEDESDIKFERIRRITGYLVGTVDRFNNAKKAEVRDRVKHR"
     gene            4310..4849
                     /gene="nrdG"
                     /locus_tag="KR231_003674"
     CDS             4310..4849
                     /gene="nrdG"
                     /locus_tag="KR231_003674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase
                     activating protein"
                     /protein_id="HBH0005997.1"
                     /translation="MKIRMSSTISYDSIVDGPGLRMVIWTQGCIHNCKECHNPQTHDL
                     CGGFYMDTEEIINKVKSLKLQKGITLSGGEPFLQPEPLEEIAKEAKINGLDVWSYTGF
                     TFEQLLDKKNRAYFKNLNLLKQIDILVDGKFIAEKKDISLKFRGSSNQRIIDVQKSLK
                     YKQVFLVEQYMKDDLSIAE"
BASE COUNT         2151 a          625 c          888 g         1861 t
ORIGIN      
        1 ttctataaac ttattaaaaa cttaatagaa atattaagca taaagattat gtggttacaa
       61 tagcagagag gatacacctg ttcccattcc gaacacagaa gttaagctct ctagcgctga
      121 tggtacttgg tgggaaactg cctgggagag taggacgtag ccacgtaatt tttttgttat
      181 aataaattta gaatttaact tatatagttt aatttgataa tttgatgaaa aaaataaaag
      241 acttattgat ttttaaatct ataggtcttt tattttttat ctaacattta aattaagttg
      301 ttgaatatat cttatattac ttaccttata tattaattat cattaataca ttatatctaa
      361 ttactattca tctaaattat tatgccatta ttttatatac aaattctttt aatttatcta
      421 atccagataa gaaagtattt tcactgcaag cataggatat acgaatatat ttatccatac
      481 caaatgctat gccaggaaca actgcaacat tatattcttc taaaaattga ttacaaaatt
      541 ctatagaaaa actatcttta tattcaaatt tctcagatac tttagaaaga tctataaata
      601 tatagaatgc gccatttgga ttcacatatc ctacattatc aatagagtct agttttgatt
      661 taattaaatc tcttcttgat ttatatgttt taaccatatt gtctatgtca attgagcaat
      721 ctttcaaggc tccataggct atgtattgtg ctgttagact tgggtgagat ataagatgtc
      781 cttgtataga actcattgct ttagcaatcg ttttattaga tgcagtatat cctaatctta
      841 atccagtcat tgcagctgac ttagaaaaac catttatagt tattgttata tctttagctt
      901 cttcgcttaa tgatgcaatt gatgtaaatt caccagtgta gcatattttt tcatatattt
      961 catctgctaa aatatatatt ttattttgta tgcatacatc tactatttct attaattcat
     1021 cttttgtata aacactacca gtaggatttg aaggattgtt tattacaaga atttttgttt
     1081 tatctgttat agatttttca agttcttctt ttgttaactt aaatccattt tcttttttag
     1141 tatcaataaa aactggaaca gcattaacta acttaatcat ttcaggataa ctaacccaat
     1201 aaggctttgg taataagact tcatctcctt cgtctgttaa agctagtaaa gtatttgtta
     1261 ttgagttttt tgctccactt gatacaacta tttcgtctat tgaatagtta cagttatttt
     1321 cttcaataag ttttttacag atttcctctc taagtatttt taatcctgga actaaatcat
     1381 atttagtgta atctttattt aaagaatcaa taccataaga ttttgcgtta ttaggtacat
     1441 taaaatcggg ttctcctata ctaagattta ttactttaac tccattactt tccatttctt
     1501 taactttaga actaatacct attgtgtagg atggtgttat aaagtttagt ctttttgata
     1561 acataaaatg cctcctttta aattattatt tatattatac gacaaattta aagaatttac
     1621 ataaggaaat ttgtagatat atacattaat atatataata gcctacactt tttgcctaaa
     1681 attagtgtaa aaaaaagaga aaaaaatttt aactttcaaa gttgttagaa acgctactgt
     1741 tcaaaatatc cacatagtat ttgcaatgat ttgcgcaagt ttgactatta tgtacaaatt
     1801 tggtaatctt aatatagcaa ttattaagat aatcccttta acttagttga aggggatttt
     1861 tttagactta acatactaca tatagtggta tggggattaa taaaatacaa tatatagtaa
     1921 caggaggttt ttttaattgg ttgaattcgt aaaaaaaaga gatggaagag taattccatt
     1981 taatgaagat agaataacaa gagctatatt tttagcagca acgaatgttg cagaaagaga
     2041 aggaatagta cctgattata aattatctga gcaattaact caagaagtaa taaagttttt
     2101 aaatcataaa tactcagaat cagttccaag tgttgaagat atacaagatt ctgtagttaa
     2161 ggttcttata gaaactggcc atgcaaaaac tagtgaagaa tatataatat acagaactga
     2221 aagaagtaga ataagaaatt caaaaacaag gttgatgaag gcaatagagg aaattacctt
     2281 tgaagatgca gaagatgctg atataaaaag agaaaatgca aatattaatg gtaatacagc
     2341 aatgggaact atgttacaat atggaagcac tgtatctaaa gaattttgta aaacacatat
     2401 attaaaacca gagcattctt ttgctcatga taatggagat atacacatac atgatatgga
     2461 ttttttaaat atgggaacat taacttgttg tcaaatagat gttaaaaaac tattcaatgg
     2521 tggattttca acaggacatg gctttttaag agagccacaa gatataataa gttatggtgc
     2581 attagctgca attgctatac aaagcaatca aaacgatcaa catggaggtc aaagtatacc
     2641 atttttcgat tatggattgg ctgaaggtgt atataagaca tttaagaaat tctacatagg
     2701 aaatttagct aaagcattaa agttatttaa aggaattgaa aataatgatg tgataaagaa
     2761 catagtatat aatacagaga aagaaacaaa tcaaaaagtt ggtcttaaga gagatgaatt
     2821 gtatctaaac ttagaaaaag agaaattaat acagactttt gatatagatg atgaacttgt
     2881 aaataagatg caaaactttg catttgaaga atcgtataga gaaactgata aaaaaacata
     2941 tcaatctatg gaagcattta tacacaatct aaacacaatg cactctagag caggtgcaca
     3001 ggtaccattt tcaagtgtaa acttcggaac agatacttct gaagaaggaa gaatggtaac
     3061 taagaatctt ctattatctc aagaaagagg tttaggtaat ggagagacac caatttttcc
     3121 aattttaata tttaaggtca aagaaggcat aaatttaaat cctgaagacc ctaattatga
     3181 tttatttaaa ttatcatgca gagtatcagc taaaagacta ttccctaatt ttagtttttt
     3241 agatgcgcct tttaatgcaa aatattataa aaaaggtgaa ccagatacag aagctacata
     3301 tatgggttgt agaacaagag tacttagtaa tgtgtgtggt tcagaaacag ttagtggtag
     3361 aggaaacata tcttttacta cagtaaattt accaagattg ggtataaaac atggtattat
     3421 aaataatgaa aaggctaatt tagacggttt ctttgaagaa ttagatgaga agataaactt
     3481 aattatagaa caattattgg agcgccttga ggtacaagga aataaaaaga tgaagaattt
     3541 tccattctta atggggcaag gtgtatggaa aggttctgat gatttaggac cagaagatac
     3601 actaaaagaa gtaataaaac aaggaacatt gacaattgga tttataggtt tagcagagtg
     3661 ccttattgct cttataggta aacatcatgg agaaagtaaa gaagctcaag aattaggatt
     3721 aaaaatagtg tcacatatga gacataaaat ggatgaagca acggacaaat ataaattaaa
     3781 tttctcctta atgggtactc cagcagaagg tctttcaggt aggtttacta aaatagataa
     3841 aaaagtttat ggagaaatta aaggtatcac agataaagaa tattatacta attcattcca
     3901 tgtaccagtt tattacaata taagtgcata tgataaaatt gagatagaag ctccatacca
     3961 tgaattgact aatgcaggtc atataacata tgtagagtta gatggagatc catctgataa
     4021 tttagaagct tttgaaactg ttataaaagc tatgaaagat ttgggtatag gatatggaag
     4081 tataaatcat cctgtagata gagacccaat atgcggtttt tcaggtgtaa taacaagtaa
     4141 tatatgccct gtatgtggaa gaaatgaaga tgaaagtgat atcaaattcg aaagaataag
     4201 aagaataaca ggatatttag ttggtacagt tgatagattt aataatgcta aaaaagcaga
     4261 agtaagagat agagtaaaac atagatagtt ttatttgggg gaataagtta tgaaaataag
     4321 aatgtcatct actataagtt atgacagcat agttgatgga ccaggattaa gaatggtaat
     4381 atggacccaa ggatgtattc ataattgtaa agagtgccat aatcctcaga cacatgattt
     4441 atgtggagga ttttatatgg atacagaaga aattataaat aaagtcaaat cattgaaatt
     4501 acaaaaaggc attacgctat caggaggaga accattttta caaccagaac cattagaaga
     4561 aatagcaaaa gaagctaaaa taaatgggtt agatgtatgg tcatatactg gatttacgtt
     4621 tgaacaactg ttagataaaa aaaatagagc gtattttaaa aatttaaatt tactaaagca
     4681 aattgatatt ttagtggatg gaaaatttat agctgaaaaa aaagatataa gcttaaagtt
     4741 tagagggtca tcaaatcaaa ggataattga tgttcaaaaa agtttgaaat ataaacaagt
     4801 gtttttggtt gagcaatata tgaaggatga tttatctata gcagaataaa atataaataa
     4861 acaggattaa atatatgcat atatttaatc ctgtttattt tcatataata tttcaagctt
     4921 gtataatgta acaattaaac caaaagactc attgtatatt tgaaattaag ttttttatag
     4981 tttataggtg ttttatgtgg attacgaatg atatagtatt gatacattat ttaatagatt
     5041 cttatgccaa gaaacaatta atttatagaa attcttaatt gttacaatat aaatatctag
     5101 atatgttata agatactgat aaataattta taaagtttat taatctaata ttgtgtgtga
     5161 atattaagtg gtcaagtagt ctaaaaaatg aaaaagattt aaaaaagtgt tttaactaaa
     5221 cacataagtg ttaaattcat gtataagtat aggttagata cataagaaat aattatgtaa
     5281 tatctatctt tgtaaaaaaa tattaaattt tgtaatttgt ggataaatat gtttataatg
     5341 tggataatat ttaatgtaat aagttaaagc aatatgaatc aactgtttat aatgtggata
     5401 atattataaa tgtatgaata attgcagtat ttaaaaacaa aaaaagttaa aaaagttgtt
     5461 gactctaaaa gaaaaagttg gtatagtaat acttgtcctc aagaaaaggg caaacaaata
     5521 aagca
//
LOCUS       DAEPHU010000144         5467 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 01A10CD0081
            SAMN05941466-rid12468953.denovo.146, whole genome shotgun sequence.
ACCESSION   DAEPHU010000144 DAEPHU010000000
VERSION     DAEPHU010000144.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941466
            Sequence Read Archive: SRR6291087
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 5467)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5467)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068158.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 22:43:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,892
            CDSs (total)                      :: 3,805
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 87
            rRNAs                             :: 8, 1, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 55
            CDSs (without protein)            :: 55
            Pseudo Genes (ambiguous residues) :: 0 of 55
            Pseudo Genes (frameshifted)       :: 21 of 55
            Pseudo Genes (incomplete)         :: 28 of 55
            Pseudo Genes (internal stop)      :: 16 of 55
            Pseudo Genes (multiple problems)  :: 8 of 55
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5467
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941466-rid12468953.denovo.146"
                     /strain="01A10CD0081"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            22..174
                     /locus_tag="KR231_003675"
     CDS             22..174
                     /locus_tag="KR231_003675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0005998.1"
                     /translation="MYENLLDMDRIELIRELGSIFEKMKNENPDEFYRFVSLVKEECR
                     KKRERE"
     repeat_region   468..1028
                     /inference="COORDINATES: alignment:crt:1.2"
                     /inference="COORDINATES: alignment:pilercr:v1.02"
                     /rpt_family="CRISPR"
                     /rpt_type=direct
                     /rpt_unit_range=468..497
                     /rpt_unit_seq="gttgaagaataacatgagatgtttttaaat"
     gene            1151..1678
                     /locus_tag="KR231_003676"
     CDS             1151..1678
                     /locus_tag="KR231_003676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4352 domain-containing protein"
                     /protein_id="HBH0005999.1"
                     /translation="MREGKRRRGCLFWFILIILFSGVVGAIAGNSTNNESTEKQKEDL
                     TKYIGEEGSIGDLKLTVNSISKASEISVASGYLAYTPDSGKYGIINLTIKNQTKESQS
                     FMLNSFTLIGPDDSKYVPSLLIDVGNKYITMDTVNPNLDVTGNIAFEIPKDLLVSDCK
                     LKYSGSEQEFILKEK"
     gene            1817..2584
                     /locus_tag="KR231_003677"
     CDS             1817..2584
                     /locus_tag="KR231_003677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4428 domain-containing protein"
                     /protein_id="HBH0006000.1"
                     /translation="MGLFGKKKADICCICNTEIGVLNIEDGWICNSCFKEYCDALSMT
                     KAPKILRKLDIEKTISSTKKNNELQKIFNTTNNIENYIEFDEDNKKWFVSKKSINDKK
                     TPIIHSYEDIVEFELLENGETVTKGGIGRALAGGILFGEAGAIVGGITGKKTTRKVVD
                     TFKIKITINNIDNPIEYIELINKKTKTNSSAYEKAYKDAHKILSILSAITQSIKETDN
                     INTKSVADEILKYKNLLDMEAITQDEFNTKKKELLNL"
     gene            2650..5022
                     /locus_tag="KR231_003678"
     CDS             2650..5022
                     /locus_tag="KR231_003678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tape measure protein"
                     /protein_id="HBH0006001.1"
                     /translation="MATIQTSIKIFDGMTPAFRNMTNSINTTINSLERLQGRLNNPLN
                     AGNIQASQQSLNNIESILTRIEQKIGRNTNEQENFNNKIRQGSEAGSLLVSKLKSLAG
                     IYIGIRGIESITKAADTIASTKARLNLMNDGLQTTEQLNKMIYLSAQSARASYADTAA
                     QVSKLGILAGEAFGSSAEVVKFAELMNKSFVIGGTSASEASAAMYQLTQAMVAGKLQG
                     DEFRSIMENAPLLATKIAESMGKGKEALKDLSRTGAITADVVRNALFKASAEIEKKFE
                     SMPITFSQALTMMKNDAYMIFGQTLGKISGALQSVRFSEIVVSIRNVMIAISSNIYDT
                     LNIIKNILNSEFFSNLVQGFTFCVVVITKSLGSIVNTALNIVNIFAQNWSIIKPIVFG
                     VASVFILFRGVLLATKIATIGNVIANVAHAASSSLSALMTNIQAAALMRSNGATLSAT
                     IATWGLNAALLACPITWVVLGILAFVVVVFVAVAAVNKFAGTSLTALGVIVGAVFAAV
                     AAIQNVMIWLLNGCIAVNEGITNGWNQCVYLMKQAIAKGVIFIIEKMASLNDSVNNAG
                     NALGKAFVAGANIAIRGVNKLIDLLNKIPGVNIGKVGEATFTPVKADNSYIKQQIDSL
                     NKWVGDAPEKIKLDRMGYKDIGAEFQKGNALGTKWQNAITDKFKDTFDINKMLEDAKK
                     KLGLDDLWNKQNPLNNLGGFGGDLGKNVKDTAGNTAKMAKTMDKSQEDLKYLRDIAEQ
                     ETINRFTGVNIKIDMNNTNNISKDTDVDGIVNVLTEKLNDAMIVSAEGIV"
     gene            5038..>5467
                     /locus_tag="KR231_003679"
     CDS             5038..>5467
                     /locus_tag="KR231_003679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan-binding protein"
                     /protein_id="HBH0006002.1"
                     /translation="MAYDFYLDGVQLPIPPPKLEIKVTNKNKIVDLINTGEVNILKKE
                     GLSEISFEAEFTHNKLPFYRGAFRDVQFFLSKLELLKTDCKPFQFIVSRELGNKVLFN
                     TNIKVSLEEYAISEDAENGSDTKVAIKLKQYRDYSTKKLVL"
BASE COUNT         2163 a          593 c         1015 g         1696 t
ORIGIN      
        1 gttttgaggg ggattaatac aatgtatgag aatttacttg atatggatag aatagaactt
       61 attagagaac ttggaagtat ctttgaaaaa atgaaaaatg aaaatccaga tgaattttat
      121 agatttgtaa gtttagtgaa agaagaatgt aggaaaaaaa gagaaagaga ataaataata
      181 tagataaagc acttataagt acataaaagt gctttatctt ccaaaatatg ctataattgt
      241 agtatcaaat atatagggtg attacgcatc ctaagtgtga gattatccca agcaattgga
      301 attgatactc acaaagatga ttactaaata aagtaattat caccgtccca ataaacattg
      361 ggtaaaaaca tctgaaattt aaaaacactt gggataaatt tgattaatgt tagtatttac
      421 aatggttatg ttgttttatt ttatttaaga atgtgcattt ttaagtggtt gaagaataac
      481 atgagatgtt tttaaatagt attagaaata cttcgcttgt ttggaaatca taagttgaag
      541 aataacatga gatgttttta aattcatcta aaagtttagc ccaagtttga actgctatcg
      601 ttgaagaata acatgagatg tttttaaatc tatctcttct tttaccttct ataaaattta
      661 attgtgttga agaataacat gagatgtttt taaatctatt agttacttta tagcttacat
      721 agtaaatgcc tgttgaagaa taacatgaga tgtttttaaa tactgtttct ctgttcgaag
      781 tatgtgctac atctccaagt tgaagaataa catgagatgt ttttaaatga aagccacgct
      841 tgcgcattag actgtttgaa gttggttgaa gaataacatg agatgttttt aaattgaata
      901 aattcttttg tatttttatc aaaatacggc tcgttgaaga ataacatgag atgtttttaa
      961 atatgtgttg aagcagaagc ttttgagaat ggtttagagt tgaagaataa catgggatgt
     1021 aaaaataaat atttatataa aacacttact taaatagtag gtgtttttta attgaaagga
     1081 tgtgattata atgtaaaaat tttgaagata tagtataata ttcttataaa atataattta
     1141 gggggatatt atgagagaag gaaagagaag aagaggatgt ctattttggt ttattcttat
     1201 tattttattt tctggagttg ttggagcaat agcagggaac agtactaata atgaaagcac
     1261 tgaaaaacag aaagaggatt taactaaata tattggtgaa gaaggtagta taggagattt
     1321 aaaattaact gttaatagca tttcaaaagc tagtgaaata tcagtagcat ctggttattt
     1381 agcatacact ccagatagtg gcaaatatgg tattataaat ttaacaataa aaaatcaaac
     1441 taaggaaagc caatctttta tgctaaattc attcacatta ataggaccag atgattcaaa
     1501 atatgttcca tctttattga ttgatgtagg aaataaatat ataactatgg atactgtaaa
     1561 tcctaattta gatgtaacag gtaatattgc atttgaaatt cctaaggatt tactagtttc
     1621 tgattgtaaa ctaaaatata gtggttcaga gcaagaattt atattaaaag aaaaataata
     1681 tatagattta aaaatatgaa gcatttactt taaataagta agtgcttttt taattgaaag
     1741 gaggtgataa taatgtaaaa attttactta tatagtataa ttacattata aaattattgt
     1801 actggggggg aatcttatgg ggttatttgg aaagaaaaaa gcagatatat gttgtatttg
     1861 taatactgag ataggagtac tgaatattga agatggttgg atatgcaatt cttgttttaa
     1921 agaatattgt gatgcacttt ctatgactaa agcacctaaa attttaagaa aattagatat
     1981 tgaaaagact atatcatcaa ctaaaaaaaa taatgaactt caaaaaatat ttaatacaac
     2041 taataatata gaaaactata tagaatttga tgaagataat aaaaaatggt ttgtgtctaa
     2101 aaaaagtata aacgataaaa aaactcctat cattcattct tatgaagata tcgtggaatt
     2161 tgaacttctt gaaaatggtg aaactgtaac taaaggagga ataggaagag ctttagcggg
     2221 aggaatttta tttggagaag caggagctat agttggaggg ataacaggta aaaaaacaac
     2281 aagaaaagtt gttgatacat ttaaaattaa aataacaatt aataatattg ataatcctat
     2341 tgagtatatc gaattaatta ataaaaaaac aaaaactaat tctagtgctt atgagaaagc
     2401 ttacaaagat gcccataaaa ttttatcaat attatctgct attacacaaa gcattaaaga
     2461 gacagacaat ataaatacta aatctgtagc agatgagata ttaaaatata agaatctttt
     2521 ggatatggaa gctattacac aagatgaatt taatactaag aaaaaagaat tattgaattt
     2581 gtaatataat aaacacttac taatgtaggt gtttttttat atggaaattt atgaaaggag
     2641 agtgaggaaa tggctacaat acaaacttca ataaagattt tcgacggaat gacaccagca
     2701 tttcgtaata tgactaattc tattaataca acaattaata gtttagagag attgcaaggc
     2761 agattgaata atccactcaa tgcaggtaat atacaagctt ctcaacaaag tttgaataac
     2821 atagaaagta ttctcacaag gatagaacag aaaattggaa gaaatacaaa tgaacaagaa
     2881 aactttaata ataaaataag acaaggaagt gaagcaggct ctctattagt atctaaactc
     2941 aaaagtttgg ctggcatata tattggaata agaggtatag aaagtattac aaaagcagca
     3001 gatacaattg caagtacaaa agcacgttta aatttaatga atgatggatt acagacaaca
     3061 gaacaactta ataagatgat ttatttatct gctcaaagtg ctagggcttc ttatgcagac
     3121 acagcagcac aagtatctaa gttaggaata cttgcaggag aagcttttgg aagtagtgca
     3181 gaagttgtaa aatttgcaga gttaatgaat aagagtttcg taattggagg aacatcagca
     3241 tcagaagcta gtgcagcaat gtatcagtta acgcaagcta tggtagcagg aaaattgcaa
     3301 ggtgatgaat ttaggtctat catggaaaat gcaccacttc tagctactaa aatagctgaa
     3361 tctatgggta agggtaaaga agcactaaaa gatttgtctc ggacaggtgc tattacagca
     3421 gatgtagtga gaaatgcttt gtttaaagca agtgctgaaa tagaaaagaa attcgaaagt
     3481 atgccaataa cttttagtca agcacttact atgatgaaaa atgatgctta tatgatattt
     3541 ggtcagacat taggaaagat aagtggagca ttgcaaagcg ttagatttag tgaaattgtt
     3601 gtatctataa gaaatgttat gattgcaata tcttcaaaca tttacgatac attaaatatt
     3661 ataaaaaata ttttaaatag tgaattcttt tcaaacttag tacaaggatt tacattttgt
     3721 gtggtagtaa taactaaaag cttaggttct attgtaaata ctgcattaaa tatagttaat
     3781 atatttgcac aaaattggag tataataaaa cctattgtat ttggtgtagc ttctgttttt
     3841 atattgttta gaggggtttt gctagcgact aaaatagcta caataggtaa cgtaattgcg
     3901 aatgttgctc acgctgcttc ctcttcacta tcagcactta tgactaatat acaagcagca
     3961 gcactgatgc gttcgaatgg agctacttta tcagcaacaa tagccacttg gggtttaaat
     4021 gcagctttat tagcttgtcc aatcacatgg gtagtattag gtattctagc atttgtagta
     4081 gtagtttttg ttgcagtagc agcagtaaac aaattcgcag gtacaagttt aactgcctta
     4141 ggagtaattg tgggtgctgt atttgcagca gtggcagcaa tacaaaatgt tatgatatgg
     4201 ctactgaatg gctgtatagc tgtaaatgaa ggcattacaa atggttggaa tcaatgtgta
     4261 tatcttatga aacaagctat tgcaaaaggt gtaatcttta taatcgagaa aatggcatct
     4321 ctaaatgatt ctgtaaataa tgcaggaaac gcacttggta aggcttttgt ggctggggcg
     4381 aatatagcaa tcagaggagt aaataagctt attgatttac taaacaaaat tcctggagta
     4441 aatattggga aagttggaga agcaacattt acgcctgtca aggcagataa tagttacatc
     4501 aaacaacaga ttgacagttt aaataaatgg gtaggagatg caccagaaaa aataaaattg
     4561 gatagaatgg gatataaaga tattggagca gaatttcaaa aaggaaatgc acttggaact
     4621 aaatggcaaa atgctataac tgataaattt aaagatactt ttgacattaa taagatgcta
     4681 gaagatgcaa agaaaaaatt aggattagac gatttgtgga ataaacaaaa tcctttaaac
     4741 aaccttggtg gatttggtgg agatttagga aaaaatgtaa aagacacagc aggaaacaca
     4801 gccaaaatgg ctaaaacaat ggataaaagt caagaagacc ttaaatactt aagagacatt
     4861 gcagaacaag aaacaataaa cagattcaca ggagtaaaca taaaaattga tatgaacaat
     4921 actaacaata taagtaaaga cacggatgtg gatggtatag taaatgtttt aacagaaaaa
     4981 ctgaatgatg ctatgattgt atcagcagaa ggaatagttt agaaaggagg gatataaatg
     5041 gcttatgact tttatttaga tggagtacaa ttaccaatac ctccgccaaa gttagagatt
     5101 aaagttacaa ataaaaacaa gatagttgat ttgataaata ctggagaagt aaacatacta
     5161 aaaaaagaag gattatctga aataagtttt gaagcagaat ttacacataa taagttgcca
     5221 ttctatcgtg gagcttttag ggatgttcaa ttctttttaa gtaaactgga actattaaaa
     5281 actgattgta agccatttca atttattgta tcgagggaat taggtaataa agtactattt
     5341 aacactaata taaaagtatc tcttgaagag tatgctattt cagaagatgc agaaaatggt
     5401 tcagatacaa aagttgcaat aaagttaaag caatatagag attactcaac taaaaagtta
     5461 gttcttg
//
LOCUS       DAEPHU010000145         5400 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 01A10CD0081
            SAMN05941466-rid12468953.denovo.147, whole genome shotgun sequence.
ACCESSION   DAEPHU010000145 DAEPHU010000000
VERSION     DAEPHU010000145.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941466
            Sequence Read Archive: SRR6291087
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 5400)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5400)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068158.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 22:43:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,892
            CDSs (total)                      :: 3,805
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 87
            rRNAs                             :: 8, 1, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 55
            CDSs (without protein)            :: 55
            Pseudo Genes (ambiguous residues) :: 0 of 55
            Pseudo Genes (frameshifted)       :: 21 of 55
            Pseudo Genes (incomplete)         :: 28 of 55
            Pseudo Genes (internal stop)      :: 16 of 55
            Pseudo Genes (multiple problems)  :: 8 of 55
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5400
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941466-rid12468953.denovo.147"
                     /strain="01A10CD0081"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            478..1338
                     /locus_tag="KR231_003680"
     CDS             478..1338
                     /locus_tag="KR231_003680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HBH0006003.1"
                     /translation="MKIIQILNNNVALVKRGKNEIIVFVKGIGFKKRVGQVINENEIE
                     RTYILDSYDMLEHFSYLLQNSDSNNIVLINEIIEYGEKALNIKASDYLSLTLLDHLEF
                     LLKRCEKNQFIKSPLVWNVKRFYPKHFEIGMHALKLIGDSKGINLPDDEAVSIALHFV
                     NMEVNKESHDSTIVELRTLADIVSIIKYHFNVELDETSTNYMRFTTHLQYFIQRIMSD
                     EASIDEDNSIDLYKQVSQLYPKSFGSVQKIRKYIKSQFNVDISISEETYLMLHINRVT
                     QRLEAKSDEI"
     gene            1328..3199
                     /locus_tag="KR231_003681"
     CDS             1328..3199
                     /locus_tag="KR231_003681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HBH0006004.1"
                     /translation="MKYKDLNENIIKLIGGKENIKSVAHCVTRLRFTLNDRSIAQTEE
                     IKKLKGVIDVVSNDVAYQIIIGTHVVDVYNEFMSMIGLSSSESSIKSERKKGIRGIKG
                     IFNSIFVVVSETMTSVIEVLLAAGILASILALLNMSGILQSDSPTYQILDTLRSATFH
                     FLPVLIAIASAKRLNVNPYIAVVLAVTLLSSSIDGVEGLSLFGINLQATTYANSFIPI
                     LLGVWAMGIIIEGLKKILPKALHYFLVPVLSLIITLSVTLTVFGPIGMWIGDGLNYAC
                     MFLIDTLGNWSVVALYAALQPLLIVFGAANFTMPISLNSVTTLGYDPIFMGAATISDI
                     AVCGAMFGYFLKTRNKEQKQLFGTVSFSALMGVTEPSVFGVFMKYRRPFVAVMIGGGI
                     GGLIAGLAQVKTYGMVWGLAALPTYLVGGEVSNFTFMIISVVVSFVAATAASYLLGIP
                     SDEKEEVKGDNEKELELIINENNSRTISIGNVAKGQVIALGEVNDKAFSSGALGKGVG
                     VIPSESKSTVISPVDGTITIVFPTKHAYGIVTDEGLEILIHIGIDTVNLDGKFFESLV
                     TQNQRVKKGDALAVFESDKIIEEGFDSTIITVVTNTSDYLDVISSNDESEELLTVIV"
     gene            3219..4673
                     /locus_tag="KR231_003682"
     CDS             3219..4673
                     /locus_tag="KR231_003682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="family 1 glycosylhydrolase"
                     /protein_id="HBH0006005.1"
                     /translation="MNIKDTFFWGGSIAAHQCEGSWDSDNKGPAIMDFVTKGSYETPR
                     VITDKIEEKLDYPSHNGIDFYNRYKEDIALFKEMGFSALRISIDWSRIFPNGDDENPN
                     ELGIKYYEGLIDTLIENNIEPIVTLYHFELPMNLVHKYGSWNNRKLIDLYLKYSETVI
                     RRFDDKVKYWVTFNEMNHIDPQTEHSDIFTYMIAGIKYSEIENKVQTLANVGYNMTLA
                     GVKVAKLAREINPNNKIGCVFGLNPIYPYNCNPSNVLNAFLDNDRDYYQIDAMCNGKF
                     PQYKLKEYEKNNITIEVTDEDKKAFKEGKLDFIGLNYYFSSVSTPKENLSGDKSLFGG
                     IQNPYLEQSKWGWAIDPIGLRFTLNYIYRKYQLPILITENGLGAYDKIEEDGTINDDY
                     RIEYLSKHLSQMKSAIEEDNVECFGYLMWGPIDLVSATTGQMSKRYGFIYVDLDDEGK
                     GSFKRYKKKSFDWYKEVIKSNGEVLDFSTDIVVG"
BASE COUNT         2095 a          547 c          959 g         1799 t
ORIGIN      
        1 aactaaattt gaagctttac ctattaatat atcttaatag tgattaaata aaactaaact
       61 taagacttta tatgttaata tatcttaaga atttatttgt taacatacag ttcattatat
      121 ttaaaagcat tactatgata attcataata gtaaaataga taatggttca gacaatatta
      181 taaatattag tgacggtaaa atagtatcaa tttagtatat aaaccttgtc agataatcgc
      241 ataacagagc ttgtagttat agaataaaaa aatatctagg aaaccgttga cagatttata
      301 tggatagtat aacatataga atatgaaatt aaacaaaaaa gaattttaat tatggcgacg
      361 tagtcataat tttgagtatg ttactgatta gcaggcagaa ctcaagtata tatgtgaaaa
      421 atagagggat actctataca tatatgcttg agttcttttt attgaaagga ggaatatatg
      481 aaaataattc agattttaaa taataatgta gccttagtaa aaagaggtaa aaatgaaatt
      541 attgtatttg ttaaaggaat tggctttaaa aaaagagtgg gacaagtaat aaatgaaaat
      601 gaaatagaga gaacatatat actagattca tacgatatgc tagaacactt tagttatcta
      661 ctacaaaact cagactccaa taatatagtt cttattaatg aaataattga atatggtgag
      721 aaagctttaa atataaaggc aagtgattat ctaagcttaa ccttactaga ccatttagag
      781 tttttactta aaagatgtga aaagaatcaa tttataaaaa gtcctttggt atggaatgtt
      841 aaaagatttt atccaaagca ttttgaaatt ggaatgcatg cactaaaatt aattggtgat
      901 agtaagggaa ttaatcttcc tgatgatgag gcagtatcaa tagcacttca ttttgtaaat
      961 atggaggtaa ataaagagtc tcatgatagt acaattgtag agttgagaac tttagcagat
     1021 atagtttcta taataaaata tcattttaat gtagagctag atgaaacttc aacaaattat
     1081 atgagattta ctactcatct acagtacttt atccaaagaa ttatgtcgga tgaagcttca
     1141 atagatgaag ataattctat agatttatat aaacaagtaa gtcaacttta tccaaagtca
     1201 tttggaagtg ttcaaaagat aagaaaatat ataaaatcac aatttaatgt cgatatatct
     1261 ataagtgaag aaacttattt aatgttgcat ataaataggg tgactcaaag actggaggca
     1321 aaatcagatg aaatataaag atttaaatga aaatataata aaacttatag ggggaaaaga
     1381 aaatataaag tcggtagcgc attgtgttac tcgtttaaga tttactttaa atgataggag
     1441 tatcgctcaa acagaagaaa ttaaaaaatt aaaaggagta attgatgtag tttctaatga
     1501 tgttgcttat caaattataa taggtactca tgttgtagat gtatataacg agtttatgtc
     1561 tatgataggt ttaagttcaa gtgaatcaag tataaaaagt gaaagaaaaa agggaattag
     1621 aggtatcaaa ggtatattta attccatctt tgtggtagtc tcagagacta tgacttcagt
     1681 aattgaagta ctacttgcag ctggtatact tgcaagtata ttagcacttt taaatatgtc
     1741 tggcatactt cagagtgaca gtcctacata tcaaatatta gatacattaa gaagtgctac
     1801 atttcacttc ttaccagtat taattgcaat agcatcagca aaaagactta atgtaaatcc
     1861 ctatatagca gtagtgttag cagttacgtt attatcttca tcaatagatg gtgtagaagg
     1921 attaagttta tttggtataa atttacaggc tacaacttat gcaaacagtt ttattccaat
     1981 acttttagga gtatgggcaa tgggaattat aattgaaggt ttgaaaaaaa tattacctaa
     2041 agcattacac tattttttag ttccagtgtt atctttaata ataactctat cagttacatt
     2101 aactgtattt ggacctattg gtatgtggat tggtgatgga ttaaactatg catgtatgtt
     2161 tttaattgat acattgggta attggagtgt tgttgcactg tatgcagctt tacaaccact
     2221 cttaatagtt tttggtgcag caaactttac tatgcctata tctttaaatt ctgtgacaac
     2281 attggggtat gacccaattt ttatgggcgc tgcaacaata tctgatattg cagtttgtgg
     2341 tgcaatgttt ggatatttct taaaaactag gaataaagaa caaaaacaac tatttggtac
     2401 agtaagtttt agtgcactta tgggagttac agaaccttca gtgtttggtg tgtttatgaa
     2461 atatagaaga ccatttgtag cagtaatgat aggtggaggt ataggtggtt taatagcagg
     2521 tttagctcaa gttaaaacat atggaatggt ttggggatta gctgcattac caacgtatct
     2581 tgttggagga gaggtatcta actttacatt tatgataata agtgtagtag tatcatttgt
     2641 agcagcaaca gcagcttcct atttactagg aataccttca gatgaaaaag aagaagttaa
     2701 gggtgataat gaaaaagaat tagaactaat aatcaacgag aacaattcaa gaactattag
     2761 tattggaaat gttgcaaaag gtcaggtaat tgcacttggg gaagttaatg acaaagcatt
     2821 ttcctctgga gcattaggta aaggggttgg agttatacct agtgaatcaa aatcaactgt
     2881 tatatctcct gtagatggaa ctataactat agtatttcca actaaacatg catatggtat
     2941 agtgactgat gaaggattag aaatattaat tcatattggg atagatactg taaacttaga
     3001 tggaaaattc tttgaaagtc ttgtaacaca aaatcaaagg gttaaaaaag gagatgcttt
     3061 agcagtattt gaatctgata aaattataga ggaaggcttt gattctacta taataactgt
     3121 agttacaaat actagcgatt atttagatgt aatctcatca aatgatgaat cagaagaatt
     3181 attaactgta atagtataaa ttttaggagg gaaaattcat gaatattaaa gatacatttt
     3241 tctggggagg aagtattgca gcccatcaat gtgaaggttc atgggatagt gataacaaag
     3301 gacctgcaat tatggacttt gtaactaagg gctcttatga aacgccaaga gtaattactg
     3361 ataaaataga agaaaaatta gattatccat ctcataatgg aatagatttt tataatagat
     3421 ataaagaaga tatagcttta tttaaagaaa tgggatttag tgcattaaga atatctatag
     3481 attggtcaag aatttttcca aatggagatg atgaaaatcc taatgaatta gggattaaat
     3541 actatgaagg tctgatagat acattaatag aaaataatat agaacctatt gtaacactat
     3601 atcattttga attacctatg aatttagtac ataaatatgg ttcatggaat aacagaaaac
     3661 ttatagattt gtatttaaag tacagtgaga ctgtaataag aagatttgat gataaggtaa
     3721 agtactgggt tacatttaat gagatgaacc atattgaccc tcaaacagag cactcggata
     3781 tttttactta tatgatagca ggtattaagt atagtgaaat agaaaataag gttcaaacat
     3841 tggcaaatgt agggtataat atgactttgg cgggtgtaaa ggttgcaaag ttggctagag
     3901 aaatcaatcc caacaataaa attggatgtg tatttggact aaatccaatt tatccataca
     3961 attgtaatcc tagtaatgtg ttaaatgcat ttttagataa tgaccgtgat tattatcaaa
     4021 ttgatgcaat gtgcaatggg aagtttccac aatataaatt aaaagaatat gaaaaaaata
     4081 atataactat tgaagtgact gatgaagaca aaaaagcatt taaagaaggt aagttagatt
     4141 ttataggact taattattat ttttcaagtg tatctactcc aaaagaaaat ttatcaggtg
     4201 ataaatcttt atttggtggg attcaaaatc catatttgga acaaagtaag tgggggtggg
     4261 caatagaccc tataggttta agatttacct tgaactatat ttacagaaag tatcaattac
     4321 ctatcttaat tacagaaaat ggtttagggg catatgataa aatcgaagaa gatggaacta
     4381 taaatgatga ttatagaatt gaatatttaa gtaagcatct atctcaaatg aagtctgcaa
     4441 ttgaagaaga taatgttgaa tgttttggat atttgatgtg gggaccaatt gatttagtca
     4501 gtgcaactac aggtcagatg agtaagagat atggatttat ctatgttgac ttagatgatg
     4561 aaggcaaagg aagttttaag agatataaga aaaaatcatt tgattggtac aaagaagtaa
     4621 taaaatctaa tggagaagtt ttagattttt ctacggatat agtagtaggg taggaataag
     4681 ataaatagaa gttaggaact aatgttaatt agtgtctagt aaagcattta aaatagagta
     4741 tagggtcttt aaagtaaagt gtgtattctt cttaaaaata atggcaatta aaattactat
     4801 aaaaaggaga atacacattt tttattttta tacttaagta aatatttaga catattcata
     4861 gtataattta ctcattatat aaaaatagta tgatttactc actatataac tttataaatt
     4921 ttctggaaaa atgtcagaat atattgacaa agaaaagatt taaaattata atctatatta
     4981 agaatagttt gacaatataa aaacaagtat ttttataaat agtgaaatta tttttattgt
     5041 caatttaaga ataatttagg actactataa agataaaggt atagatgtca ttatatgata
     5101 aattatactt gtatagaaag aattttaaag tatggcttat cattgattta atataataaa
     5161 taatttttgt ttttagtaat agtctctagg aataagatat ctaaattcgc ttagaaatag
     5221 tctaatttac aagggagggg atgcactaat agataaaatt tctatataaa gaagacttaa
     5281 agtgaagtat attctgataa tattggttta atgggtatat tattatttcg ttttagatat
     5341 tttaagaata atttaagacg tttataaaaa tatattctat atctaatatt taaataaata
//
LOCUS       DAEPHU010000146         4840 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 01A10CD0081
            SAMN05941466-rid12468953.denovo.148, whole genome shotgun sequence.
ACCESSION   DAEPHU010000146 DAEPHU010000000
VERSION     DAEPHU010000146.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941466
            Sequence Read Archive: SRR6291087
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 4840)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4840)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068158.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 22:43:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,892
            CDSs (total)                      :: 3,805
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 87
            rRNAs                             :: 8, 1, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 55
            CDSs (without protein)            :: 55
            Pseudo Genes (ambiguous residues) :: 0 of 55
            Pseudo Genes (frameshifted)       :: 21 of 55
            Pseudo Genes (incomplete)         :: 28 of 55
            Pseudo Genes (internal stop)      :: 16 of 55
            Pseudo Genes (multiple problems)  :: 8 of 55
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4840
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941466-rid12468953.denovo.148"
                     /strain="01A10CD0081"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            151..1701
                     /locus_tag="KR231_003683"
     CDS             151..1701
                     /locus_tag="KR231_003683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GGDEF domain-containing protein"
                     /protein_id="HBH0006006.1"
                     /translation="MRYKKRNIDKSSELSFQSLAKYFITFYIVIILIILSMFCINTIW
                     VMKKDNQDLLSTTSNRIEDRVGETIKLLNSLSKDNYIIDNSVNGIDKSKELSMYSDEF
                     GYMMICFVDKNIIVWDEEGGNISLAGRDYMQKLFATKKYQVTDSFAAGADGKTLNYTI
                     ASPIIKNGNVDGCVFAAIYFDEIKDILKQGKGQQQQNFILFGSENQIMNLTSDETAYG
                     EKYMKLSQKTKYLGTNAKKVEKDMFNNKSGDYWAFENGKLYFMSYKPIKNTNWSLFCK
                     VNFLDIFALNLIPMGAILSVITLVFIILICMEKSFMKKRMEVIDMLLGSVQELEKRIY
                     QTERPSEVDFKEIIQLTSKGLTDGLTGVVTRTVFFDQIYNRVEMEENDKLSVISFVDL
                     DDLKCINDLYGHEIGDMVLKNVGYVLREYEIKYNGLIGRYGGDEFVMLLSGFTSREEV
                     EDLLDEIAIRLHTEVLTDDGIIQTHCSVGAVVCSVKDNKDIDNLLKQADEALYYVKRN
                     GKGNYHLV"
     gene            1727..4429
                     /locus_tag="KR231_003684"
     CDS             1727..4429
                     /locus_tag="KR231_003684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728915.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EAL domain-containing protein"
                     /protein_id="HBH0006007.1"
                     /translation="MKNVSKKFFVCTIIVLITFLCFSKFAIYVFDKQEKKETKVVENM
                     LNVYKNNIILNLTEKFNYSKDLTSVLVSNNYSIDKLKPIADEILKNNSCIYISVVEKY
                     NVAAFFSNSVKKDIINTPIQELNYSYSLANSIKGLVVEGPSKDQFSNGDVFLITNPIY
                     KNGEYWGEITVALDAKKVVDSFNLNKLKESGFEYELWRVHLDNGSKSTIEISTKDFNF
                     SKSHEIKFKLPTVWTLSIVYKNGWNNKNIDFIVFVILLIISILIGVMTFIYIEKKSIS
                     KELNQQSLKNLETGILNREGFLIKLQEHLNRKNNEIVLLYICITNYSKFAPVMSFEKR
                     QDYLTHIVKNLDNYIKSSHFIARISEEGFVLALEENCDKNELLNIEKGISLELLRKIK
                     VENKQVFLTIGYGSSRCVDDRKDAESLLLSAIEDYERRFPAMSPIHDFTKKCEDMLDE
                     KKQIVFGEYPDLEINKLSKVIYKYYKKVQRIMYKDYNIDIGNRRGYMRDVEVLIDYNS
                     ERMLYLFLIDICKFGKFNELFSIEIGDVILKEVSNKLKTIFSNYLYRINGDVFLGISI
                     DKESYLDTLHKVNEVFNSSLSVEDVLFDVKCNIGICQYPYHGENPYDLLEKVQIALEY
                     AKKDVKSNVKVYDKELTEEIYHENNIIKDLKKGLEEQTLEVWYQPIFNVSKNCYIKAE
                     ALIRLRNKEGGYYSAYEVITYAEKHGLIKDVGLYVLKKACDVTTKIKDKNIDFEQMQL
                     NLSAQQIVHKQCANDILSCIENCGLDKKYISVEVTEKVLMETFEIVNVTLDKLKKEGI
                     SIALDEFGSGFSSINYLANLPIENLKIDKELVEQITYSKKQFELLKTIVQITKINGMD
                     IVAEGVETKETLDLVVTSGVNLIQGHYFSEPLSEDKFIELMIEE"
BASE COUNT         1880 a          434 c          839 g         1687 t
ORIGIN      
        1 aataggatat aaaaaataat attgtaaaaa aaagtttata tttagtaatg aaaatttaac
       61 gttttacttg aaattatgtg ttttgtaatg tattattaag gctctaatag gaacattttc
      121 atcaattttt ctatagtggg ggtaggaatt atgaggtaca aaaaaagaaa tatagataag
      181 tcaagtgaac tttcatttca atctctagca aaatatttta taactttcta tatagtaatt
      241 atattaatta ttctttctat gttttgtata aatacaatat gggttatgaa aaaagataat
      301 caagatttat tatctacaac atcaaatcgt attgaagata gggtaggaga aacaattaag
      361 ctattgaact ctttgagtaa agataattac ataatagata atagtgtgaa tggcatagat
      421 aaaagtaaag aactttcaat gtatagtgat gaatttgggt atatgatgat atgttttgtt
      481 gataagaata taattgtgtg ggatgaagaa ggtggtaata ttagtctagc tggtcgtgat
      541 tatatgcaga aactttttgc aacaaaaaaa tatcaagtta cagatagttt tgcagcaggg
      601 gctgatggaa aaactttaaa ctacactatt gcatcaccta taataaagaa tggaaatgta
      661 gatggttgtg tatttgcagc aatttacttt gatgagataa aggatatact caaacaagga
      721 aaaggtcaac agcaacagaa tttcatatta tttggaagtg aaaatcaaat aatgaattta
      781 acaagtgatg aaactgcata tggagagaag tatatgaagt tatcgcagaa aacaaaatat
      841 cttggaacca atgcaaaaaa agtagaaaag gatatgttta ataataaatc aggtgattat
      901 tgggcttttg aaaatggaaa attatacttt atgtcctata aaccaattaa gaacacaaat
      961 tggagtttat tttgtaaagt taatttctta gatatttttg cattaaattt aattcctatg
     1021 ggagctattc tatctgttat aactttagta tttattattt tgatttgtat ggagaaaagc
     1081 ttcatgaaaa aacgaatgga agttattgat atgcttttag gttctgttca agaattagaa
     1141 aaacgtatat atcaaacaga aagacctagt gaagtagact ttaaagaaat tattcagctc
     1201 acaagtaaag gtctgactga tggattaact ggtgttgtaa cacgtactgt attttttgac
     1261 caaatttata atcgtgttga aatggaggaa aatgataaat tatctgtaat ttcatttgtt
     1321 gatttagatg atttgaaatg tattaacgac ttatatggac atgaaattgg ggatatggtt
     1381 ttgaaaaatg ttggatatgt acttcgtgaa tatgagataa aatataatgg tttaattggg
     1441 cgctatggtg gagatgaatt tgttatgttg ttatctggtt ttacatcgag agaagaggtg
     1501 gaggatttat tggatgagat tgctattcgc ttacatactg aagtactaac agatgatggt
     1561 atcattcaaa ctcattgtag tgttggagct gtagtatgta gtgtaaaaga caataaagat
     1621 atagataatt tattaaaaca ggctgatgaa gctttatact atgttaaacg taatggaaaa
     1681 ggtaattatc atttagttta atgtatgtgg aaggagttta tatcatatga aaaatgtatc
     1741 taaaaaattt tttgtatgta ctattattgt attaataaca tttttatgtt ttagtaaatt
     1801 tgctatttat gtttttgaca aacaagaaaa gaaagaaaca aaagtagtag aaaacatgtt
     1861 aaatgtctac aagaataaca ttattttaaa tctgactgaa aaatttaatt atagcaaaga
     1921 cttgacatca gttttagttt caaacaatta ttctatagat aaattaaaac ctattgcaga
     1981 tgaaattctt aaaaacaatt cttgcatata tatttcagtt gtagaaaaat ataatgtagc
     2041 tgcatttttt tctaattctg tcaaaaaaga tattatcaat actccaatac aggaactgaa
     2101 ttattcttat tcattagcaa attctatcaa aggattagtc gtagaaggtc cttctaaaga
     2161 ccagttttca aatggagatg tgtttttaat tactaatcct atttataaaa atggagagta
     2221 ctggggagaa attacagtag ctttagatgc caaaaaagtt gtagattctt ttaacttaaa
     2281 taaattaaaa gaatctggat ttgagtatga actttggcgt gtacacctag ataatggttc
     2341 aaaatctaca atagaaattt ctactaaaga ttttaatttt tccaaatcac atgaaattaa
     2401 gtttaaactt ccgactgttt ggactcttag cattgtgtac aaaaatggat ggaataataa
     2461 gaatatagat tttattgtat ttgttatatt gttaattatt tctatattaa taggtgtgat
     2521 gacatttatt tacattgaaa agaagtcgat tagtaaggaa ttaaatcaac agagtcttaa
     2581 aaatttagaa actggtattt tgaatagaga aggtttttta attaagttgc aagagcatct
     2641 gaatagaaaa aataatgaaa tagtgttgct gtatatatgt attactaatt atagtaaatt
     2701 tgctccagtt atgagctttg aaaaaagaca agattatctt acacatatag taaaaaatct
     2761 agataattac ataaaaagtt ctcattttat tgctcgtata agtgaggaag gttttgttct
     2821 agctttagaa gaaaattgtg ataaaaatga attgcttaac attgaaaaag ggatttcctt
     2881 agagctttta cgaaaaatta aagtagaaaa taaacaagta tttttaacga ttggttatgg
     2941 ctcatctagg tgtgttgatg atagaaaaga tgcagaatct ctgttacttt cagctattga
     3001 agattatgag agaagatttc cagcaatgtc tcctattcat gattttacta aaaagtgtga
     3061 agatatgctt gatgaaaaga aacagattgt atttggtgaa tatccagatt tagaaataaa
     3121 caagttgtct aaagtaatat acaaatatta taaaaaagta cagcgtatta tgtataaaga
     3181 ttataatatt gatattggaa ataggcgagg gtatatgcgt gatgtcgaag tattaattga
     3241 ttataattct gagagaatgt tatacttatt tttaatagac atatgcaagt ttggaaaatt
     3301 taatgaactg ttttctattg aaataggaga tgttatttta aaagaagtta gtaacaaatt
     3361 aaaaacaatt ttttctaatt atctatatcg tattaatgga gatgtatttt taggcatttc
     3421 aatagataaa gaatcttact tagatacttt acataaggtt aatgaagtat ttaatagttc
     3481 tttaagtgta gaagatgtac tttttgatgt aaaatgtaat attggtattt gtcaatatcc
     3541 atatcatggt gaaaatccat atgaccttct ggaaaaggta caaattgcat tggagtatgc
     3601 aaaaaaggat gtcaaaagta atgttaaagt ttatgataag gaattgacag aagagattta
     3661 ccatgaaaat aatattatta aggatttaaa aaaaggtctg gaagaacaaa cactagaagt
     3721 ttggtatcag ccaattttta atgttagtaa aaactgttat ataaaagctg aggcactaat
     3781 tagattgaga aataaagagg gcggttatta ttctgcctat gaagttatta cttatgcaga
     3841 aaagcatgga cttattaagg atgtaggtct atatgtacta aaaaaggctt gtgatgtaac
     3901 tacaaaaata aaagataaaa atatagactt tgaacaaatg caattaaatt tatctgctca
     3961 gcagattgta cataagcagt gtgcaaatga catattatca tgtattgaga attgtggtct
     4021 agataaaaag tatatttctg ttgaagttac agaaaaagta cttatggaaa cttttgaaat
     4081 tgtaaatgtt actcttgata aactaaaaaa agaaggcatt agcatagctt tagatgagtt
     4141 tggttctgga tttagtagta taaattatct ggcaaattta cctattgaaa atttaaaaat
     4201 agataaggaa ttagtagaac aaattaccta ttctaaaaaa caatttgaat tattaaaaac
     4261 tatagttcaa attactaaga ttaatggcat ggatattgta gcagaaggtg ttgaaacaaa
     4321 agaaactctg gatttagttg taacttcagg tgtgaatttg attcaaggtc attatttttc
     4381 agaaccttta agtgaagata aatttattga acttatgatt gaagaataaa ggttaataaa
     4441 ataaagattt aaggtattga aaaataatta aaagtattta ataatagaat tagggaagaa
     4501 taagtttata agtaaaaaca attgattagt agttaataaa ataaatgtga tatccaaata
     4561 aatcctaaat ctaatttgag ttttaatata gatagtctaa agtttgatta ttaaagattt
     4621 aattgtaagt tgttacagtt gatgatattg attagagatt aaagtttaga gtagaaagtt
     4681 accttaaatt taaaaatgca agataaccca atctaaaaat tataatcact cgataggttt
     4741 aaggatttat ttgtttatta taaataggag ggtgtctcaa aatgaacttt ttagtttatg
     4801 aggcactctc ttttatatag aattaaatat attttattat
//
LOCUS       DAEPHU010000147         4828 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 01A10CD0081
            SAMN05941466-rid12468953.denovo.149, whole genome shotgun sequence.
ACCESSION   DAEPHU010000147 DAEPHU010000000
VERSION     DAEPHU010000147.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941466
            Sequence Read Archive: SRR6291087
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 4828)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4828)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068158.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 22:43:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,892
            CDSs (total)                      :: 3,805
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 87
            rRNAs                             :: 8, 1, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 55
            CDSs (without protein)            :: 55
            Pseudo Genes (ambiguous residues) :: 0 of 55
            Pseudo Genes (frameshifted)       :: 21 of 55
            Pseudo Genes (incomplete)         :: 28 of 55
            Pseudo Genes (internal stop)      :: 16 of 55
            Pseudo Genes (multiple problems)  :: 8 of 55
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4828
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941466-rid12468953.denovo.149"
                     /strain="01A10CD0081"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            239..1390
                     /locus_tag="KR231_003685"
     CDS             239..1390
                     /locus_tag="KR231_003685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HBH0006008.1"
                     /translation="MEIYLDNSATTKPYQEVIDKMVYALNTEYGNPSSVHRKGVEVEK
                     AIKEVRQDIAKSLGAKEKEIYFTSGGTECNNTIIRGITSLNKKRKNHIISTNIEHPSV
                     LNTLKDLEEDGFEVTYLEVGKDGKINIEDLKNAIKSTTCLVSMMHVNNEIGTIQPIGE
                     VGKYLKGLKEKIYFHVDAIQSYGKINFRLSKYNIDFMSVSAHKFHGPKGIGFMYIKEN
                     NRLKPMLTGGGQEIGIRSGTENVPGIYGLGEAVRILNKDLDVVISKVNNLKNILKNEI
                     IDNIEDIKINSPEDGVCHILNVSFRGTKGEVLLHYLEQKGIYVSTGSACSSKKKGSYV
                     LNAIGLTNEEINGTIRFSLSDMNTEEEMLEAVKVLKESICDLRSIMKRK"
     gene            1436..2611
                     /gene="thiI"
                     /locus_tag="KR231_003686"
     CDS             1436..2611
                     /gene="thiI"
                     /locus_tag="KR231_003686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 4-thiouridine(8) synthase ThiI"
                     /protein_id="HBH0006009.1"
                     /translation="MVYNILIVKYGEIGVKGKNRYIFENRLIRNIRNMLKPIGRFNVY
                     KEYGRIYVDLEDYDYEEVIEEVRKVFGIVGVCPGVRAKKDYDTLKEIALKMLEEKIEA
                     GYKTFKVESRRGDKSFGLTSQEMSMDIGGYLLSKVGDRINVDVRNPEVKIKCEYREFH
                     TMVYSDTIPGYGGLPLGTNGRAMSLLSGGIDSPVATWMVAKRGMEVEAVHFHSYPFTS
                     ERSQEKVKDLAKILAKYCGRVRLHKVNILEIQKAIGENCNEEEATILSRRFMMRIAQR
                     LSEKRHCDALITGESIGQVASQTIQGLTCTNAVVDLPVFRPLIAMDKSDIVDIAKKIG
                     TFETSILPEEDCCSVFSPRKPVTKPRLEKIEKSETALDIEKLVQDAIDKIEVEDIEF"
     gene            2767..3570
                     /locus_tag="KR231_003687"
     CDS             2767..3570
                     /locus_tag="KR231_003687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin-type N-terminal cleavage/methylation
                     domain-containing protein"
                     /protein_id="HBH0006010.1"
                     /translation="MNKKGFTLIELLVVISIIGILVIVAVPALFRNIEKSKAVTCLSN
                     RENIKTQIVIAMAEESSKGKNEVMKEVLENKDGKYFETEPKCKSGGIYSATFDDGYDG
                     ITGIESIAKVYVTCTKHPDGVEMARDIHQSMKDLIASFSQDPSIIPGASKGNDDFRKY
                     LLDNKYKNGWPTIPDEFKAKYGLSKDTLYIQPYAYSPTKSDATVVVFANNKTGGNWYT
                     SLVYDYDEGRWYKGKNGISVAGRSWDVDTDSVKSVKTEIHSKEGWGPLN"
     gene            3813..4454
                     /locus_tag="KR231_003688"
     CDS             3813..4454
                     /locus_tag="KR231_003688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase"
                     /protein_id="HBH0006011.1"
                     /translation="MNNNFQDNQTINLIQSRRSIRKFTTEQISDEQVNTLLHCAFAAP
                     SGCNKQPWHITVVQDQKLLKEISDDTLSRIHEVSNVEINKNFKLFYGAPTVLFISYDE
                     SSSWAPYDIGILTGNITTAAQALGLGSCIIGMVRGLFTPVEQGDIEGLVSVLDKEDVK
                     ESESIKMKFDTNKKYRELLDIPEGYSVPFGIAVGIPDGNLPNAREVVYKVSRV"
BASE COUNT         1935 a          454 c          927 g         1512 t
ORIGIN      
        1 tatataatat attattttat catatattgt attttataat atatttttgt agggtatagt
       61 ataagtatat tatattttac tataaaaatt tgtaataaag tgaaaaaact agcttttcat
      121 gaaataatat tttataattt aagattgtct ttttaataaa gattaacaaa aaaaatacta
      181 taattagtgg tataatagtt agagttgaag attttaaata aaggtaggtg taattaagtt
      241 ggaaatatac ttagacaata gcgcaactac aaaaccttat caagaagtta tagataaaat
      301 ggtttatgca cttaatacgg aatatggaaa tccttcttct gtccatagaa aaggtgtaga
      361 agttgaaaaa gctataaaag aagtaagaca agatatagct aaatctctag gagcgaaaga
      421 aaaggagatt tattttacat caggtggtac agagtgtaat aatactataa taagaggtat
      481 tactagttta aataaaaaaa gaaaaaatca cataatatct actaacatag aacatccttc
      541 tgttttaaat acattaaaag atttagaaga agatggtttt gaagtaactt atttagaggt
      601 cggaaaagat gggaaaataa atatagagga tttaaaaaat gcgataaagt caactacatg
      661 cttagtaagc atgatgcatg ttaacaatga aataggaact atacagccaa taggtgaagt
      721 tggaaagtat ttgaagggtt taaaagaaaa aatttatttc catgttgatg ctattcagtc
      781 atatggaaaa attaatttta gactatctaa atacaatata gattttatga gtgtaagtgc
      841 acataaattt catggtccaa agggaattgg atttatgtat ataaaagaaa ataatcgcct
      901 taagcctatg ttaacaggtg gtggtcagga aattggaatt aggtcgggaa cagaaaatgt
      961 acctggaata tatggtcttg gagaagctgt tagaatacta aacaaagatt tagatgttgt
     1021 tatttcgaaa gtaaataact taaaaaatat attaaaaaat gaaataattg ataatataga
     1081 agatataaaa attaattctc cagaagatgg agtatgtcat atattaaatg tatcatttag
     1141 agggacaaaa ggagaagttt tacttcatta cttagagcaa aagggtattt atgtatcaac
     1201 tggctctgca tgttcttcta aaaagaaagg tagttacgta ttaaatgcta taggtcttac
     1261 aaatgaagaa ataaatggaa caataagatt tagtttatct gatatgaata cagaagaaga
     1321 aatgttagaa gctgtgaaag ttttgaaaga atcaatttgt gacttaaggt caataatgaa
     1381 aagaaaataa agaatactgt atagatagtg ataataaatt agtttaagag gtgaaatggt
     1441 gtataatata ttaatagtaa agtatggaga aattggagta aaaggaaaga atagatatat
     1501 atttgagaat aggcttataa gaaacataag aaatatgtta aaaccaattg gaagatttaa
     1561 tgtatataaa gagtatggaa gaatatatgt tgatttagaa gactatgatt atgaagaagt
     1621 aattgaagaa gttagaaaag tatttgggat agtgggtgtg tgccctggag taagagctaa
     1681 aaaagattat gatacattaa aagaaatagc tttaaaaatg ttagaagaaa aaatagaggc
     1741 tggatataaa acttttaagg tagagtcaag aagaggagat aagtctttcg ggttgacttc
     1801 tcaagaaatg agtatggata taggtggata cttattatca aaggtaggag ataggattaa
     1861 tgttgatgta agaaatccag aagttaaaat aaagtgcgaa tacagagaat ttcatactat
     1921 ggtctatagt gatactatac ctggatatgg tggattgcca cttggaacga atggtagagc
     1981 tatgtctctt ttatcaggag gtatagatag cccagtagct acatggatgg ttgcaaaaag
     2041 aggtatggaa gtagaggcag ttcactttca tagttatcca tttacaagtg aaaggtcaca
     2101 ggaaaaagtt aaggatttag ctaaaatact ggcaaaatac tgtggtagag taaggcttca
     2161 taaagttaat atcttagaaa tacaaaaagc aattggcgag aattgtaatg aagaagaagc
     2221 tactattctt tcaagaagat ttatgatgag gatagcacag agactttctg aaaaaagaca
     2281 ttgtgatgct ttaattacag gtgaaagtat tgggcaggtt gcatctcaaa ctatacaagg
     2341 acttacttgt actaatgccg ttgtagactt accagtgttt agaccactta tagcaatgga
     2401 taaatcagat atagttgata tagccaaaaa aatagggact tttgaaacat ctatattgcc
     2461 tgaagaagat tgttgtagtg tattttctcc tagaaagccc gtcactaaac ctagattaga
     2521 gaaaatagaa aaatctgaaa cagcacttga cattgaaaaa ttagtacagg atgctattga
     2581 caaaatagag gtagaggata ttgagtttta gcatacaagt tatttaatta ctaaattgaa
     2641 tattgagtat attagtagtt ctgtaagtat attagtagtt ctgttgaaag gatttatgta
     2701 gacaatttat taatatgtag tatttaaaaa taagtactat aattttattt aatgggaatg
     2761 attattatga ataaaaaggg ttttacacta attgaattgt tagtagttat atctataata
     2821 ggcattttag ttatagtagc tgttccagca ttgtttagaa atatagaaaa aagtaaagca
     2881 gttacatgtc tttctaatag agaaaatata aagactcaaa ttgttattgc aatggctgag
     2941 gaatcaagta aaggcaagaa tgaagtcatg aaagaggtat tagaaaacaa agatggtaag
     3001 tactttgaaa cagaaccaaa gtgtaagtca ggtggaatat attcagcaac gtttgatgat
     3061 ggttatgatg gaataactgg aatagaaagc attgcaaaag tgtatgttac ttgtacaaaa
     3121 catccagatg gtgttgaaat ggctagggat atacatcaaa gtatgaaaga tttgattgca
     3181 tcattttcac aagacccttc tataatacca ggagcctcaa agggtaatga tgattttaga
     3241 aaatatttat tagacaataa atataaaaat gggtggccta caattccaga tgaatttaag
     3301 gcaaaatatg gattaagtaa ggatacacta tatatacaac catatgcata tagtcctact
     3361 aaatctgatg ctactgtagt tgtatttgca aataataaga ctgggggtaa ttggtatact
     3421 tccctagttt acgattatga tgaaggtaga tggtataaag gtaaaaatgg tatttctgtt
     3481 gcaggtaggt catgggatgt tgacacagat agtgttaagt ctgtaaaaac agagattcat
     3541 tctaaagagg gatggggtcc tttaaattaa tatatcatgt tttattaatc tggtattgat
     3601 taaactatag aaaagagcag tttctataga tgacgaatac cagattttca tttatatata
     3661 taattgagat atattaaaag tgtttatatt tttaagtctt cacatacaag ctaaaaataa
     3721 ttataataat attgtaaaga aatttaatta taagattaat tttctgaaga tttagtattt
     3781 gtactaagaa atacataaaa aggggaatag atatgaataa taattttcaa gacaaccaaa
     3841 caataaattt aatacaaagt cgtagaagta tacgaaaatt tacgacagaa caaattagtg
     3901 atgagcaagt aaacacatta ttacactgtg catttgcagc accttcagga tgtaataaac
     3961 agccttggca cataactgtt gtgcaagacc agaaactttt aaaagagatt agtgatgata
     4021 ctttatctag gattcatgag gtgagtaatg ttgagataaa taaaaacttt aagttatttt
     4081 atggtgctcc aaccgtttta tttatttctt atgatgaaag tagttcatgg gctccatatg
     4141 atataggaat acttacaggg aatataacaa cagctgcaca agcactaggg cttggaagtt
     4201 gtataatagg aatggttaga ggtttattta cacctgttga acaaggggat attgaaggtc
     4261 ttgtgagtgt attggataaa gaagatgtaa aagaatcaga gtcaataaag atgaagtttg
     4321 atacaaataa aaaatacaga gaactacttg atataccaga agggtattct gtaccatttg
     4381 gtattgctgt aggtattcca gatggaaatt taccaaatgc tagagaggta gtttataaag
     4441 tttccagagt ttaggataaa gtattgcaag aaccaatcag ttacttgaag aattaaacca
     4501 gtaatataca aataaattga tggaagagga agctatttaa aaagtagttt agatttttcg
     4561 ttgtaaaata attaaataaa gaataaggtg ataagtattt tatttattat cttattcttt
     4621 tttatttttg ttttgtagaa tgataaaaat aaggattaag tgtaataaaa tagaaaacaa
     4681 gtatgttaat tttaagtata tgctttaaaa tttatccaag ttaaaaattt aagatatctt
     4741 ttcagtataa tggaaaaaat gtcaaaatat tgaaataggg aaaaaatagt gatataataa
     4801 gaaaaaatag agaaaaaaag taaccctt
//
LOCUS       DAEPHU010000148         4498 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 01A10CD0081
            SAMN05941466-rid12468953.denovo.150, whole genome shotgun sequence.
ACCESSION   DAEPHU010000148 DAEPHU010000000
VERSION     DAEPHU010000148.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941466
            Sequence Read Archive: SRR6291087
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 4498)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4498)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068158.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 22:43:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,892
            CDSs (total)                      :: 3,805
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 87
            rRNAs                             :: 8, 1, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 55
            CDSs (without protein)            :: 55
            Pseudo Genes (ambiguous residues) :: 0 of 55
            Pseudo Genes (frameshifted)       :: 21 of 55
            Pseudo Genes (incomplete)         :: 28 of 55
            Pseudo Genes (internal stop)      :: 16 of 55
            Pseudo Genes (multiple problems)  :: 8 of 55
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4498
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941466-rid12468953.denovo.150"
                     /strain="01A10CD0081"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            84..752
                     /locus_tag="KR231_003689"
     CDS             84..752
                     /locus_tag="KR231_003689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0006012.1"
                     /translation="MENITSYFTTILCVFICLSSVFIFTQLARVFINKKKINQKIKSR
                     NGFRYDRDFIEARREEIHIKDNNNNKNKSNNKKLKEEKVFKYDNGDLYKGEFVDGKKN
                     GFGIYIFSGKEKYEGLWKDDKMHGIGKYTYRDGSIYTGEFKYGLKNGLGKLTYPNNDI
                     YKGYFLDNKKNGKGVLYKNDGNKQAGIWEDDEQCKSLDFKDLNNNKINNVYQNRLNNN
                     KLKV"
     gene            911..1417
                     /locus_tag="KR231_003690"
     CDS             911..1417
                     /locus_tag="KR231_003690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3'-5' exonuclease"
                     /protein_id="HBH0006013.1"
                     /translation="MKEYVVVDLETTGLDPYKGCEIIEIGITEIKNEQIVKNYSRLIK
                     PKGIISSFITELTHISNEMVENEEPLELVLPRFRKYIGDRTIIAHNAKFDLKFLNYYL
                     RMLDLEPINNYICTVELLKKCKSYKGKNKKLETACAYYNIENINAHRADSDTLATAKL
                     FLKIKDEY"
     gene            1545..2561
                     /locus_tag="KR231_003691"
     CDS             1545..2561
                     /locus_tag="KR231_003691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transglycosylase domain-containing protein"
                     /protein_id="HBH0006014.1"
                     /translation="MGYYNDNDNNKIRRKKISNNKDSNKKSKHSYTSANKKNKSPNTS
                     SSKRMSEKVDSQNLIKRDRDSFTRDNVRPLNTDYNQRERRRVEYKQREKKLKSKKRKK
                     QKRIRIVRALLSIMLVALIIFSVAGAIFTVSAIKGSPEVTKKLIRSKYISSEVVSIKQ
                     MPNDLKHAIVSIEDERFYKHKGVDVISLVRSVLNNVFTDTTQGASTIDMQVSKNLLTS
                     NDKTMKRKIRDMYNAKQMNKIMTKDEILEAYLNNMYLGKNAYGAAKGAEVYFGKKVSE
                     LNLAECAMLAGMTNNPARYIDHGEAKKRQVIVLYKMHQLGYITDKEYRIAKADDTPFK
                     SEID"
     gene            2915..3619
                     /locus_tag="KR231_003692"
     CDS             2915..3619
                     /locus_tag="KR231_003692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="B3/4 domain-containing protein"
                     /protein_id="HBH0006015.1"
                     /translation="MKKFVIEDAFWNLFPSAKIGVVICNDIDNSIKDEDYKKIILKGE
                     EEALKYLEDSEFSNNQVIKVWREAFKKFKTKKGARSSIEALLKRVHNGNNIGTINPLV
                     DIYNFISLKYALPCGGEDIDKFIGDIRLTRAIGNEEFIPLGTDENSFPYEGEIIYKDD
                     GGAICRCWNWREAVRTMLTEDTNNAFLCIELVDESRFKEFENALNELAKIVQEKLGGN
                     CKISILDIDNKEVSVD"
     gene            3914..4393
                     /locus_tag="KR231_003693"
     CDS             3914..4393
                     /locus_tag="KR231_003693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2975 domain-containing protein"
                     /protein_id="HBH0006016.1"
                     /translation="MSNKLIKNLLSGILQILFFLLGLVIVVGGFKSFMYLCFSGEATL
                     QGTIYGILMFILGVSYFIIIKSLIEVLGSSEYSLFVKENVKRFRIIGYLLLLNSLIEF
                     ISTFGTTGKGMRFLDLGFGFYFTVPVFVYFITSLMSFVIADGFVKAIKIKEDNDLTI"
BASE COUNT         1892 a          377 c          764 g         1465 t
ORIGIN      
        1 tactataaaa gtataaataa catttaataa aaatatatat tatattaggt attttaaata
       61 aattttttaa agggtgattt tttatggaaa atataactag ttattttaca acaatactat
      121 gtgtatttat atgcttatca tctgtattta tatttactca actagctaga gtatttatta
      181 ataagaagaa gattaatcaa aaaattaaat caagaaacgg atttaggtat gatagagatt
      241 ttattgaagc cagaagagaa gaaatacata taaaggataa caataataat aaaaataaga
      301 gtaacaataa gaaattaaag gaagaaaaag tatttaaata cgataatggt gatttatata
      361 aaggtgagtt tgttgatgga aagaaaaatg gatttggaat atatattttt tcaggtaagg
      421 aaaagtatga aggattatgg aaagatgaca agatgcatgg aataggaaaa tatacttata
      481 gagatggttc aatatataca ggtgaattta aatacggatt aaaaaatggt ttgggaaaat
      541 taacatatcc caataatgac atttataagg gatatttttt agataataag aaaaatggta
      601 agggtgtatt atataaaaat gatggaaata aacaagcagg aatatgggaa gatgatgaac
      661 aatgtaaaag tttagatttt aaagatttaa ataataataa aataaataat gtttatcaaa
      721 atagattaaa taacaataaa ttaaaagttt aattattcta ataaaaaaat ctttatttat
      781 gatggaatat aggatatatc tatgttgtaa tttgtaaaat cttcctatat catataaaat
      841 taagtattga ttagtctatt acataaatat agaatataaa tatatccatt taataataag
      901 gagaagagat atgaaagagt atgtagttgt ggatttagaa actacaggat tagatccata
      961 taaaggttgt gaaataatag aaataggaat aacagaaata aaaaatgaac aaattgtaaa
     1021 aaactattca aggttgataa aacctaaggg gataatttct tcatttataa cagaattgac
     1081 acatataagt aatgaaatgg tagaaaatga agaaccacta gaattagttt tacctagatt
     1141 tagaaaatac ataggtgata gaactataat tgcacacaat gcgaaatttg atttaaaatt
     1201 tttaaattac tatcttagaa tgttagattt agaaccaata aacaattata tatgtacagt
     1261 agagttatta aaaaaatgta aaagttataa aggaaaaaac aagaaacttg aaacagcttg
     1321 tgcttattac aacatagaga atataaatgc tcatagagct gacagtgata cattagcaac
     1381 tgcaaaacta tttttgaaaa taaaagatga atattaatta taaatataga gaaaattagt
     1441 gaaaatatcc tttataaaat tgacccttaa gcttacaatt ttgttctttg atttattttg
     1501 tagaacaatg tataatgtac cttatatgaa gaagggagac taaaatgggt tattacaatg
     1561 ataatgataa taataaaata agacgtaaaa aaattagtaa caacaaagat agtaataaaa
     1621 aatctaaaca ttcttatact tcggcaaata aaaaaaataa aagtcctaat acaagttcca
     1681 gtaaaagaat gagtgaaaaa gtagattcac agaatcttat aaaaagagat agagatagtt
     1741 ttacaagaga taatgtaaga cctttaaata cagattacaa tcaaagagaa agaagaagag
     1801 tcgagtataa acaaagagag aaaaaattaa aaagtaaaaa aagaaaaaaa caaaaaagga
     1861 ttagaatagt tagggcatta ttatctatta tgttagttgc actaattata ttttcagtgg
     1921 caggtgcaat atttacagtt tcagctataa aagggtcacc agaagttact aaaaagttaa
     1981 ttaggtctaa atatataagt agtgaggttg taagtataaa acaaatgcca aatgatttaa
     2041 aacatgcaat agtttccata gaagatgaga gattttataa gcataaagga gtagatgtta
     2101 tttctctagt taggtcagta ttaaacaatg tgtttacaga tacaacacaa ggtgcaagta
     2161 ctatagatat gcaagtttca aaaaacctgc ttactagtaa tgataaaact atgaagcgga
     2221 aaataaggga tatgtataat gctaagcaga tgaataagat tatgactaag gatgaaattc
     2281 ttgaagcata tttaaataat atgtatctag gtaaaaatgc atatggagct gcaaagggag
     2341 ctgaagtcta ctttggtaaa aaagttagtg aattaaattt agctgagtgt gctatgttag
     2401 ctggtatgac aaataatcct gcaaggtata ttgaccatgg agaggctaag aagagacaag
     2461 tgattgtact gtataagatg catcagcttg gttatataac tgataaggag tatagaatag
     2521 caaaagctga tgacactcca tttaaatcag aaattgatta aaattgtaag aatatagtat
     2581 tttcaatagt ttaaacaaac aaaaatgtaa taaaaaaggt gatttgccac ccatttgcca
     2641 ccataattat aatctaatgg caaattgttt taatgtacaa actagataat agaatattgt
     2701 cttaaatgct atattatgct aaaatttaat tgtattttgt aaattaaaaa acttataatt
     2761 tagttttcta gggttccgca ttttataatg gtcaggtcca agagaaaacg cgcaattgtt
     2821 gtgtacacgg aaggataaaa gcctgggaga tatttaagaa tatttctata ggctttttta
     2881 tttttacata ttttaaattt gaggaggttt tctaatgaaa aaatttgtta ttgaggatgc
     2941 attttggaat ctatttccta gtgcaaaaat tggagttgtt atttgtaatg atatagataa
     3001 ctctataaaa gatgaagact ataagaaaat aattttgaag ggagaagaag aagcattaaa
     3061 atacttggag gactcagaat ttagcaacaa ccaagtgatt aaagtatgga gagaagcatt
     3121 taaaaaattt aaaacgaaaa aaggagcaag gtcttctatt gaagcattat taaaaagagt
     3181 tcataatgga aataatatag gaactattaa ccctttagtg gatatctaca attttatctc
     3241 attaaaatat gcattacctt gtggagggga ggatatagat aaatttatag gagatattag
     3301 gctaactaga gcaattggta atgaggagtt tatcccacta gggacagatg aaaattcatt
     3361 tccatatgaa ggagaaataa tttataaaga tgatggtgga gcaatttgta gatgttggaa
     3421 ttggcgtgaa gcagtgagaa caatgcttac tgaagatact aacaatgcct ttttatgcat
     3481 tgaattagta gatgaaagta gatttaaaga atttgaaaat gctttaaatg aattagctaa
     3541 aatagttcaa gaaaaattgg gtgggaattg taaaatttca attttagata ttgataataa
     3601 agaggtatca gtggattaat atggaggtgc tgttgtaatg gactattcta gttataaaga
     3661 tacttatatt tagggtaaga aggtctattt tagatataac gattatcaaa ggatataata
     3721 tagaaaataa aaatgtagaa tataaaaagc ctttaaaata agaaaaaaat gtattttaaa
     3781 ggcttttatt atactctttt ttatttgcat aattaacaat aaaaatatat tgttaattat
     3841 aatattttta tttaaaaacg atataatata atgtattata ctatatataa aatattttaa
     3901 aggagttggc atgatgtcta ataaacttat aaaaaattta ctaagtggta tattacaaat
     3961 tttatttttt cttttaggat tagtaattgt tgtaggagga tttaaaagtt ttatgtacct
     4021 ctgttttagt ggagaagcaa ctctacaagg tactatttat ggaatattaa tgtttatttt
     4081 aggtgtatca tattttatca ttataaaatc attgatagaa gtattaggta gttctgaata
     4141 tagcctattt gtaaaagaga atgtaaaaag atttaggatt attggatatc ttttgctttt
     4201 aaactctcta attgagttta tttcaacttt tggtactact ggaaaaggaa tgagatttct
     4261 agatttagga tttggatttt attttactgt tccagtattt gtatatttta taacttctct
     4321 gatgagtttt gtaattgcag atggatttgt aaaggcaata aagataaaag aggataatga
     4381 tttaactatt taggtgtgac actttaatat ataggagata aataacccga aaagagtgac
     4441 taactagtaa tttaaaataa aatatattag ggtataatac ataaactata atgctaaa
//
LOCUS       DAEPHU010000149         4365 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 01A10CD0081
            SAMN05941466-rid12468953.denovo.151, whole genome shotgun sequence.
ACCESSION   DAEPHU010000149 DAEPHU010000000
VERSION     DAEPHU010000149.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941466
            Sequence Read Archive: SRR6291087
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 4365)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4365)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068158.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 22:43:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,892
            CDSs (total)                      :: 3,805
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 87
            rRNAs                             :: 8, 1, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 55
            CDSs (without protein)            :: 55
            Pseudo Genes (ambiguous residues) :: 0 of 55
            Pseudo Genes (frameshifted)       :: 21 of 55
            Pseudo Genes (incomplete)         :: 28 of 55
            Pseudo Genes (internal stop)      :: 16 of 55
            Pseudo Genes (multiple problems)  :: 8 of 55
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4365
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941466-rid12468953.denovo.151"
                     /strain="01A10CD0081"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            244..609
                     /locus_tag="KR231_003694"
     CDS             244..609
                     /locus_tag="KR231_003694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBH0006017.1"
                     /translation="MKIRAEYTCLLEIVHDIIKGKWKTILIFELRQSNKTFSELQHNI
                     YGINQKMLIQQLKELRDFGIIDKISSAGYPLHVEYFLTNRGKKMLKAVEIMQEIGIEY
                     MLEHGQQEILDNKGICYNK"
     gene            687..1241
                     /locus_tag="KR231_003695"
     CDS             687..1241
                     /locus_tag="KR231_003695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HBH0006018.1"
                     /translation="MSIALILIDIQNDYFKNGKCELFQSEETAENAKKILLFFRKNNL
                     PVIHIQHISTDKTASFFLPNTHGSEINKIVFPLDNEEIITKHTPDSFFETDLQSILEK
                     KNITNLVICGMMSHMCIDTSVRTAKKLRYDITLISDACTTKNLSWNNIEINANTVHQV
                     FMASLQNSFADVKNTDKFLSNYHK"
     gene            1461..2135
                     /locus_tag="KR231_003696"
     CDS             1461..2135
                     /locus_tag="KR231_003696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MgtC/SapB family protein"
                     /protein_id="HBH0006019.1"
                     /translation="MNHHILIQFEYIARIITAGFCGALIGYERKNRLKEAGIRTHFIV
                     ALASALIIIVSKYGFNDIVGTPGIGLDPARVAAQVVSGIGFLGAGLIFIRNQSVSGLT
                     TAAGIWATAGTGLAIGSGLYLVGIVSSIIIVIVQITLHRDRKWMKLPTAEQVSLKISN
                     STDSIEYIEGKFKKSNIEIINMNIKRLDGDWLEVVIYTKLPKGYKKTNLLKLFSDNPL
                     IETLEI"
     regulatory      2490..2586
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01051"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="cyclic di-GMP riboswitch class I; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="cyclic di-GMP"
                     /db_xref="RFAM:RF01051"
     gene            2640..2816
                     /locus_tag="KR231_003697"
     CDS             2640..2816
                     /locus_tag="KR231_003697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0006020.1"
                     /translation="MFRDEMDKCTHMLTAYISSLYDYCDFIDTQLDDFILEYGENVVE
                     SCLHQVMVLVSKYN"
     gene            complement(3004..3243)
                     /locus_tag="KR231_003698"
     CDS             complement(3004..3243)
                     /locus_tag="KR231_003698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0006021.1"
                     /translation="MKCSNCGSVNIEKGILTTGGIYAETIGLKYRGDGKLDKVINKTF
                     PVQSTIYSDLCLDCGEIVRTYIKDNTDRNWCKDKK"
     gene            complement(3377..4186)
                     /locus_tag="KR231_003699"
     CDS             complement(3377..4186)
                     /locus_tag="KR231_003699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HBH0006022.1"
                     /translation="MKDYYKIGEISKIYGIGRDSLMYYEEIGILRPVRDINGYRMYNI
                     SDIWKLNLIKEFRSLNFPMKKIKEYLDDRSIESTKNILNEELDLIDKKIAEFISHKEN
                     IIKRLSSIESVIQNTKIDEIEVVYIEKRKALELNADIKRDEDFDFLIQKLQKEYEDRF
                     NILGNNNIGSAFSTEAINKGIFNEFKSVFCFLESNEKVYNIVFDEGYYVTLNYTGSNS
                     NNKIYMEKVFKFIEENNYKIIADPIEIYKIDIHETGIVEEFVTEIQVPITK"
BASE COUNT         1611 a          592 c          508 g         1654 t
ORIGIN      
        1 ttgatatatt catatatatt cctcctctaa attatcataa gttattttaa agttaaattt
       61 ctatagtcat gttatatatt tatttactta tatcttacta attatttatg tactaaatat
      121 gaactacaat agaagaaatt tagaacttaa taaaacataa aatttatata cagttcatat
      181 atatttgtca tatcacaaga caagtgatat aatttattat cattttactg ggggtgatat
      241 gctatgaaaa taagagctga atatacatgt cttcttgaaa ttgtacatga cataatcaaa
      301 ggaaaatgga aaactatcct tatatttgaa ttaagacaat ctaataaaac attttctgaa
      361 ttgcaacata atatttatgg aataaatcaa aaaatgttga ttcaacaatt aaaagagtta
      421 cgtgattttg ggattattga taaaataagt tctgctggat atccattaca tgttgaatat
      481 tttcttacta atcgtggtaa aaaaatgtta aaagcagtgg aaataatgca agaaatagga
      541 atcgaatata tgcttgaaca tggtcaacaa gaaattctag ataataaagg aatttgctac
      601 aataagtaat cctatacata ccaaaaagta agtaatttac attttttaca atagtattat
      661 aataaaaata aataggaggt ataatcatgt ctatagcttt aatattgatt gatattcaaa
      721 atgattattt taaaaatgga aaatgtgaat tatttcaatc agaagaaact gctgaaaatg
      781 ctaaaaaaat actactgttt tttagaaaaa acaatttacc agttattcat atacagcata
      841 tatcaacaga taaaacagct tctttttttc ttcctaatac tcatggttca gaaataaata
      901 aaattgtttt tccactagat aatgaagaaa ttataactaa acacacacca gatagtttct
      961 ttgaaacaga tttgcaaagt atccttgaga aaaaaaatat tactaatcta gtaatctgtg
     1021 gaatgatgag ccatatgtgt attgatacaa gtgtaagaac agcaaagaaa cttcgatacg
     1081 acataactct aataagcgat gcatgtacaa cgaagaattt atcttggaat aatatagaaa
     1141 ttaatgcaaa tactgtacat caagtattca tggcatcact acagaacagt tttgcagatg
     1201 taaaaaacac agataaattt ttatctaact atcacaaata aaaacataca ctatgttaaa
     1261 agagcaagtt tgatttattt aagcttgctc tttaatcatt taaaattaga tgctttctat
     1321 catttttata tacataatat acgtttatac attttatatt catatataac tattatataa
     1381 attttaaact ttactatatt cacataaaaa atgtagtatt atagtatata taatattata
     1441 tagaaggggg tgctagataa atgaaccatc atatattgat tcaatttgaa tatatagcaa
     1501 gaatcattac tgctggtttc tgtggggctt taattggata tgagagaaag aatagactaa
     1561 aagaagctgg aatacgcact cattttatag tggcattagc ttcagcactt ataatcattg
     1621 tttccaagta tggatttaat gatatagtgg gtactccagg tattggtcta gacccagccc
     1681 gcgttgcagc acaagttgtc agtggtatag gttttttagg tgctggatta atatttatta
     1741 gaaatcaatc agtaagtggt cttactacag ctgctggtat atgggcaaca gctggtacag
     1801 gtcttgccat tggctctgga ttatacttag ttggtattgt ttcaagtatc attattgtta
     1861 ttgtacagat aacacttcat agagatagga aatggatgaa actccctaca gcagagcaag
     1921 tttctcttaa aatttctaac agcactgatt ccatagaata tattgaaggt aaatttaaaa
     1981 aatctaatat tgaaattata aacatgaata ttaaacgcct tgatggggat tggttagaag
     2041 tagttatata tactaagtta cctaaaggat ataaaaaaac aaatttatta aaattattta
     2101 gcgataatcc tcttatagaa actttagaaa tataatataa aaattgaagc ttaaaaataa
     2161 taatatattt aatcaaggtc aatatataaa taattacggg atgagtctat ataaaattca
     2221 tcccttgttt tttgccattc atatatattt tttcaagata tttttgttca tctattatct
     2281 agccaagtaa ctcttgtgaa ctaaactttt taatacaaaa acttcaatac aaaactaaat
     2341 ataattttta ttaaatattc tacatgtata gtttatttct tgagtgaaaa atagatttca
     2401 tattgttaag atactgttaa atatttcaat tttctgacaa gtatgttgaa caataactta
     2461 tcctagtgta ttattttagt tgtagaataa aactaaatcg gcaaaactag agaaatttag
     2521 tgacgcaaag ctatagggac taacgcttat aaaataaact atgagttatg tcagccagtt
     2581 gccaaaaaga tattgttctt tttgttttat gaaagttttt tagggggata gtaatatata
     2641 tgtttagaga tgaaatggat aaatgtacac acatgttaac tgcttatatc agtagtttat
     2701 atgattattg tgattttata gatacacagt tagatgattt tatactagag tacggagaaa
     2761 atgtagtaga atcttgttta catcaagtga tggtattggt aagtaagtat aattaaatag
     2821 aaattgtttt ctagagaacc ctttttagtt ttatctacat ttaaaaatgt tattatatta
     2881 aaaaactaat ctcccctata tgcaaagttt tcttccatat aacaatttct tcccatttat
     2941 actttttcac ttgtatcttt aataaaattc aacttcaaat attaatatac ttcaaaaatt
     3001 attctatttc ttatctttac accaattcct atcagtatta tcctttatat aggttctaac
     3061 tatttctcca caatctaaac ataaatctga atatatagta gattgtactg gaaaagtttt
     3121 atttataact ttatctaatt ttccatctcc tctatatttt aatccaatag tttcagcata
     3181 tatgccacca gttgttaaaa ttcccttttc aatatttaca cttccacaat tagaacattt
     3241 cacatttata accccctaaa caattatttt ttcatgctat cttataattt aaaatataat
     3301 ttgctaccga ttttataaca cagtggcaaa tcaacatttt ttcattctat ttaccatcta
     3361 atccattgaa atatagctat ttagttatag gaacttgaat ttccgttaca aactcctcta
     3421 caattccagt ctcatgtata tctatcttat agatttctat agggtcagca attatcttat
     3481 aattattttc ttctataaat ttaaacacct tctccatata tatcttatta ttagaattac
     3541 tcccagtata atttaaagtt acataatatc cttcatcaaa aactatatta tatactttct
     3601 cattactttc cagaaaacaa aatacagatt taaactcatt aaatatacct ttattaattg
     3661 cttcagtaga aaaggcagaa ccaatattgt tgtttccaag tatattaaat ctatcttcat
     3721 attctttctg aagtttttga attaaaaaat cgaagtcttc atccctcttt atatcagcat
     3781 ttaattctaa agcttttctt ttttctatat atacaacctc tatctcatct atttttgtat
     3841 tttgaattac actttcaatt gaactcaatc tttttataat attttcctta tggcttataa
     3901 attcagctat ttttttatca attaaatcga gttcttcatt taaaatattt ttcgtagact
     3961 ctatacttct gtcatctagg tattctttta ttttcttcat tggaaagttc aagcttctaa
     4021 attcttttat taaatttaat ttccatatat ctgatatatt atacattcta tatccattta
     4081 tatctctaac tggtcttaga atgcctattt cttcataata cattaatgaa tctctaccta
     4141 ttccatatat tttagatatc tctcctattt tatagtaatc tttcatttat ataataaact
     4201 cctccgaaat cttattttta ttttaaatca acattattac tctataatac tatagtatta
     4261 gaatatacta aaaaaatctt taaaacaagg ataggaaaat aaacatccta ataattaatt
     4321 attaaaatat ttttatattg taatattagg tatagtattt ataac
//
LOCUS       DAEPHU010000150         4322 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 01A10CD0081
            SAMN05941466-rid12468953.denovo.152, whole genome shotgun sequence.
ACCESSION   DAEPHU010000150 DAEPHU010000000
VERSION     DAEPHU010000150.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941466
            Sequence Read Archive: SRR6291087
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 4322)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4322)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068158.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 22:43:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,892
            CDSs (total)                      :: 3,805
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 87
            rRNAs                             :: 8, 1, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 55
            CDSs (without protein)            :: 55
            Pseudo Genes (ambiguous residues) :: 0 of 55
            Pseudo Genes (frameshifted)       :: 21 of 55
            Pseudo Genes (incomplete)         :: 28 of 55
            Pseudo Genes (internal stop)      :: 16 of 55
            Pseudo Genes (multiple problems)  :: 8 of 55
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4322
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941466-rid12468953.denovo.152"
                     /strain="01A10CD0081"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            94..663
                     /gene="mocA"
                     /locus_tag="KR231_003700"
     CDS             94..663
                     /gene="mocA"
                     /locus_tag="KR231_003700"
                     /EC_number="2.7.7.76"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdenum cofactor cytidylyltransferase"
                     /protein_id="HBH0006023.1"
                     /translation="MINAVIMASGFARRMGANKLLLNYKGCSIIEHVFREVSKIDFHQ
                     VVVVSQYEEVLLLCNKYGFEYIDNKNANIGQSESIKLGVLNSSKCDGYMFFVGDQPFI
                     DNLYIDKIINTFKLDRDFIVIPRYKDMCGNPVIFPYSKKEELLALKEDEKGKTILKNS
                     SKIKYVEVPKEMLFDIDTKMDYERIGGKL"
     gene            660..1679
                     /locus_tag="KR231_003701"
     CDS             660..1679
                     /locus_tag="KR231_003701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429005.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdopterin-binding protein"
                     /protein_id="HBH0006024.1"
                     /translation="MKLIKTIDAVGQVLCHDITQIIPGEFKGRKFKKGHIVKEEDIPV
                     LLSLGKDNLYVWEKSEGMVHENEGALFLKELTAGENLDFSEIKEGKIDFIAACDGLLK
                     IDVDALFDLNCVGEIMMATLHNNFIVNKGLKVAGTRVIPLVIDEKKLEDAKKVVGNRK
                     IVNVVPFKPKKVGIVTTGNEVFYSRIVDKFGPVIEEKVKGFGCEVIGQTICPDDKEII
                     KSAIKEFISQGAELICCTGGMSVDPDDVTPTAIKETGADLVTYGSPILPGAMFLLAYY
                     GEVPIMGIPGCAMYHKTTVFDIVLSRVLIDEKLDKYDIARYGHGGLCMNCDVCTYPAC
                     NFAKI"
     gene            2017..3642
                     /locus_tag="KR231_003702"
     CDS             2017..3642
                     /locus_tag="KR231_003702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBH0006025.1"
                     /translation="MLQVTGVGLRFGDKELFKDVNLKFTKGNCYGIIGANGAGKSTFL
                     KILSGEIEPNTGSISITDKERMSVLKQDHFEYEEETVLNVVIRGHERLWNIMKEKDAL
                     YMKEDFNEEDGIKAAELEGEFAELDGWDAETNAEKILMGLGITKDMHYKQMKELVGGE
                     KVKVLLAQSLFGKPEILLMDEPTNHLDFKSINWLNNFIMDLEESIVIIVSHDRHFLNQ
                     ICTNIVDVDFGKIQMYVGNYDFWYESSQLALQLAKDQNKKTEEKIAQLKEFIARFSSN
                     ASKAKQATSRKKQLEKLEVEDIQPSRRRYPYVGFTPAREIGNEVLEVHNLTKTIDGVK
                     VLDNVSFRLDRDDKVVFMGDEIATTALFNIVMGELEPDSGEYKWGVTTSQDYLPKNHN
                     KFFDGVEYSLVDWLRQFSEEKSESFIRGFLGRMLFSGEEALKEAQVISGGEKVRCMLS
                     KLMLSNANVLVLDDPTNHLDLESITSVNKGLEKFPGVLLFTSHDHEFISTIANRIIEI
                     TPNGIMDRKMDFDEYLESKEIQDQLAKMYGKDK"
     gene            3841..4317
                     /locus_tag="KR231_003703"
     CDS             3841..4317
                     /locus_tag="KR231_003703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0006026.1"
                     /translation="MVKKRLVAVVISLAMISVGNFSYAHSGGHNSSGDHHNKNKSELT
                     RYYCGGHSAHQHNKGFCPYASTKENSGVTISSVHNEKNHKNYFAEKGYNKGYEDGCKG
                     LYNLSVTEAKSDNLYEKEILKSSYEKGYLIGYNEYKAKKVDDVMKKMLDIPMLASI"
BASE COUNT         1734 a          412 c          818 g         1358 t
ORIGIN      
        1 tttatatgat attatatata tagataatat caatagagat attataaaaa tcatagaact
       61 atcaatatat tataaatacc aaggatgata tatatgataa atgcagtgat aatggcatca
      121 ggctttgcca gaagaatggg agcaaataaa cttttattaa attataaagg ctgttctata
      181 atagaacatg tatttagaga agttagcaag attgattttc atcaagttgt agtagtaagt
      241 caatatgaag aggttttgtt attgtgtaat aaatatggtt ttgaatatat agataataaa
      301 aatgcaaata taggtcaaag tgaatctata aaattaggag ttttaaatag ctcaaaatgt
      361 gatggttata tgttctttgt aggagaccag ccatttattg ataacttata tatagataaa
      421 attataaata cttttaaatt agatagagat tttatagtaa ttccaagata caaagatatg
      481 tgtggaaatc cagtcatatt cccatatagt aagaaagaag aattgttggc acttaaagaa
      541 gatgaaaaag gtaaaaccat tttaaaaaat tcatcaaaaa taaagtatgt agaagttcct
      601 aaagaaatgt tatttgatat cgatacaaaa atggattatg agagaattgg gggtaaatta
      661 tgaagctaat aaaaactata gatgctgttg gacaagtttt atgtcacgac ataactcaaa
      721 taatacctgg agaatttaaa ggaagaaaat ttaaaaaggg ccacatagta aaagaagaag
      781 atattccagt gttattatct cttggtaaag ataatttgta tgtatgggaa aagtcagaag
      841 gaatggttca tgaaaatgaa ggcgcattgt ttttaaaaga actaactgct ggagaaaatt
      901 tagattttag tgaaataaaa gaagggaaaa tagattttat agcagcatgt gatggtctat
      961 taaagataga tgttgatgca ctttttgatt tgaattgtgt tggagaaata atgatggcta
     1021 ctcttcataa taattttata gtaaataaag gtttaaaagt agctggaaca agagtgatac
     1081 ctttagttat agatgagaaa aaattagaag atgcaaaaaa agtagttggt aatagaaaaa
     1141 tagtaaatgt agtacctttt aaacctaaga aagtaggaat tgttactaca ggaaatgaag
     1201 tgttttatag cagaattgtt gataaatttg gacccgtaat agaagaaaaa gtaaaaggct
     1261 ttggttgtga agttatagga cagactatat gcccagatga taaagaaatt ataaagagtg
     1321 caataaaaga atttataagt caaggagcag aacttatctg ttgtactggt gggatgagtg
     1381 tagacccaga tgatgttaca ccaacagcta taaaagaaac tggagctgat ttagtgacat
     1441 atggttcacc aatattacca ggagctatgt ttttacttgc ttattatgga gaagttccaa
     1501 ttatgggtat accaggatgc gcaatgtatc acaaaactac agtatttgat atagttttat
     1561 ctagggtttt aattgatgaa aagcttgata agtatgatat agctagatat ggtcatggtg
     1621 gcctttgtat gaactgtgat gtatgtactt atcctgcatg taattttgct aaaatataaa
     1681 gttattaaaa aagagtattt acaaattaag tactcttttt aaatatgaaa caaaacagct
     1741 agaatgatgt tttaagaaaa gcatatttat ttagaaatta taataactta ttttcaatgt
     1801 gtaaaagaat gaataaagtt gcaatttgat ttctttataa gtataatata agagattgtt
     1861 aatttttata aatttacaat ttttagtatt attttaataa atatttcaca aatttagtat
     1921 aaaaaatata ctatttacgt gataatatat aataaaaatg ttatcaaagt tttatgataa
     1981 aataaattat gagcaaaaag aaaggaaaat atattaatgt tacaagttac aggtgttgga
     2041 cttagatttg gtgataagga actatttaaa gatgttaact taaaattcac taaaggtaat
     2101 tgctatggaa taataggagc taatggtgcg ggaaaatcta cttttttaaa aatattatca
     2161 ggagaaatag agcctaatac aggtagtata tctataactg ataaagaaag aatgtcagtt
     2221 ttaaaacagg accactttga atatgaagaa gaaactgttt taaatgttgt tataagaggt
     2281 catgagagac tttggaacat aatgaaagaa aaagatgcat tgtatatgaa ggaagacttt
     2341 aatgaagaag atgggataaa agctgccgaa cttgaaggtg agtttgcaga gcttgacgga
     2401 tgggatgcag aaactaatgc tgagaaaata cttatgggtc ttggcataac gaaagatatg
     2461 cattacaaac aaatgaagga actagttggt ggggaaaagg ttaaggtatt gttagcacaa
     2521 tcactttttg gtaagcctga aatactatta atggacgaac ctacaaacca cttagatttt
     2581 aaatcaataa actggttaaa taattttata atggatttag aagaatctat agttataata
     2641 gtatcacatg atagacattt cctaaatcaa atatgtacta atatagttga cgtagatttt
     2701 ggtaaaatac aaatgtacgt tggaaactat gatttctggt atgagtcaag tcaattggct
     2761 ttacaactgg ctaaggacca aaataaaaag actgaagaaa agatagctca attaaaggaa
     2821 tttatagcta gatttagttc taatgcttca aaggctaaac aagcaacatc aagaaagaaa
     2881 cagttagaga aattagaagt tgaagatata caaccatcaa gaagaagata tccatatgta
     2941 ggatttacac ctgcaagaga aattgggaat gaagttttag aagtacacaa tttaactaaa
     3001 actatagatg gggttaaggt tcttgataat gtgtcattta gattggatag agatgataaa
     3061 gtagtattta tgggagatga aatagctact actgcacttt tcaacatagt tatgggagaa
     3121 cttgaaccag acagtggaga gtataaatgg ggagtaacta cttctcaaga ttatcttcca
     3181 aaaaatcata ataagttttt tgacggagta gaatattctt tggttgactg gcttagacag
     3241 ttctctgaag aaaaaagtga aagttttata agaggatttt taggtagaat gttattctca
     3301 ggtgaagaag cattaaaaga agctcaagtt atatctggag gagaaaaggt tagatgtatg
     3361 cttagtaagc taatgctttc aaatgcaaat gtacttgtat tagatgaccc taccaaccac
     3421 ttagacctag aaagtataac ttctgtaaat aaaggacttg aaaagttccc aggagtgctt
     3481 ttatttactt ctcatgacca tgaatttata tctactatag caaatagaat tatagagata
     3541 actccaaatg gaataatgga tagaaaaatg gactttgatg agtatttaga aagtaaagag
     3601 atacaagacc aattagctaa aatgtatgga aaagataaat aattattagt ataaaacctt
     3661 ttaatatttg agacatgcta tgcatgagtg tgtaaatttt taatcaaata ttaggaggtt
     3721 ttttatgttg tttaaacatg tttattagca gaatagagta atattttgta tattaagaat
     3781 ttaaatataa tatagtagat gatataataa aaatatataa cattttgggg ggaatagatt
     3841 atggttaaga aaaggttagt agctgtagta attagtttag ctatgattag tgtagggaat
     3901 ttttcatatg ctcactcagg agggcataat tcatcaggag atcatcataa taaaaataaa
     3961 tcagagttaa cacgttatta ttgtggagga cattcagcac atcaacacaa taaaggtttt
     4021 tgtccttatg ctagtacaaa agaaaattct ggagtaacaa tatcttcagt acataacgaa
     4081 aaaaatcata aaaactattt tgcagaaaaa gggtataata aaggttatga agatgggtgt
     4141 aaagggcttt ataatttaag tgtcacagaa gccaaatctg ataatttata tgaaaaagag
     4201 attttaaaaa gttcatatga aaaaggatat ttaattggat acaatgaata taaagcaaaa
     4261 aaagtagatg atgtaatgaa gaagatgtta gatattccaa tgttagcaag tatataataa
     4321 ta
//
LOCUS       DAEPHU010000151         4259 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 01A10CD0081
            SAMN05941466-rid12468953.denovo.153, whole genome shotgun sequence.
ACCESSION   DAEPHU010000151 DAEPHU010000000
VERSION     DAEPHU010000151.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941466
            Sequence Read Archive: SRR6291087
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 4259)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4259)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068158.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 22:43:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,892
            CDSs (total)                      :: 3,805
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 87
            rRNAs                             :: 8, 1, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 55
            CDSs (without protein)            :: 55
            Pseudo Genes (ambiguous residues) :: 0 of 55
            Pseudo Genes (frameshifted)       :: 21 of 55
            Pseudo Genes (incomplete)         :: 28 of 55
            Pseudo Genes (internal stop)      :: 16 of 55
            Pseudo Genes (multiple problems)  :: 8 of 55
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4259
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941466-rid12468953.denovo.153"
                     /strain="01A10CD0081"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            <1..999
                     /locus_tag="KR231_003704"
     CDS             <1..999
                     /locus_tag="KR231_003704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBH0006027.1"
                     /translation="KNLKLATSIDISNDKVFEEFLYKHISSLCKKIKLGINQSPIMAQ
                     DIKIKYPFAFELANIAKKTIEKDLKIEINEDEVANIALHIGGAVERASYNNKDKVFKT
                     IIVCTSGIGTSMLIKAKLENIFKEKLEILKIIPSYLVEYIKVIDVDFVISTVPIEVGD
                     VPVINISPILSEKEIRLIEKYIETGNIYLDLDIKSLFDSELFFTDLVFKRKEEVIDFM
                     ASKLVQKGYIDEDMKKSYFEREKIATTEIGNMVTIPHGAIGKIFDNKIAIGILKKPIS
                     WEISDVRLIIMLALDKDKILDYEVIFSKIYKRVDSIAKVISICENSSFEKFVNLFN"
     gene            1166..2083
                     /gene="pfkB"
                     /locus_tag="KR231_003705"
     CDS             1166..2083
                     /gene="pfkB"
                     /locus_tag="KR231_003705"
                     /EC_number="2.7.1.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-phosphofructokinase"
                     /protein_id="HBH0006028.1"
                     /translation="MIYTVTLNPSIDYIVKLDELKTGSTNRVKEEYVYPGGKGINVSR
                     ILKELGNDNTSLGFISGFTGEYIIRTLEEKELKTDFIKIKSGFSRINVKIKALKETEI
                     NGQGPNIDDEDIDTLYKKLDKLNQDDILILAGSIPSTLDEKLYENIMARLEKKNIKVV
                     VDATKNLLLNVLKYKPFLIKPNNDELEELFGVKLNSIEDMVKYARRLKEMGAINVLVS
                     MGKDGALLITEEDEVLISDVPKGKVKNSVGAGDSMVAGFISGYLNTGKYDYALKLGAA
                     SGSATAFSYDLAKREYIDKLVNEISVKKF"
     gene            2120..4039
                     /locus_tag="KR231_003706"
     CDS             2120..4039
                     /locus_tag="KR231_003706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBH0006029.1"
                     /translation="MKIIDLLDEKSIKLNLNSKTKSEAIEELVDLVANSGNLNDKENY
                     KKAILAREEMSTTGIGEGVAIPHAKNSSVTKACIAAAVSKEGIDYESFDGSLSNLFFM
                     IAAPDGANNTHLEVLSRLSTILMDEDFRNKLINSSSEKEFKEIIDKKEREKFSEEYQD
                     EKVAEKNIIDTKENDANKYPKVLAVTACPTGIAHTFMAAESLNKMAENKGVSIKVETN
                     GSAGVKNKLTKDEIENATCIIVAADKNVEMARFNGKKVIKTKVADGIHKAEELIDKAV
                     NGDAPIYHGGDGSHNESNEESESGFRKVYKHLMNGVSNMLPFVIGGGILIAIAFLLDD
                     YTINPSNFGSNTPIAAFFKGIGDKAFGFMLPVLAGYIAYSISDRPAFVVGFVGGALAG
                     DGGSGFLGALLAGFIAGYLVEGLKKIFSVLPASLEGIKPVLLYPLLGTLLMGIIMTFL
                     VIPPVTAINNAMVGFLNGLGGTSKIVLGLVLGGMMAVDMGGPVNKAAYVFGVASLESG
                     QFEIMAAVMAGGMVPPLAIALATTFFKNRFTKEERDSGKVNYVMGLSFVTEGAIPFAA
                     GDPLHVIPACVGGSAVAGALSMLFNAALRAPHGGVFVIPVVTHPFAYILAIAVGALVG
                     MMLLALLKKPLNQEV"
BASE COUNT         1684 a          431 c          806 g         1338 t
ORIGIN      
        1 aaaaatttaa aattagctac atcaatagat ataagtaatg ataaggtatt tgaagagttt
       61 ttatataagc atattagtag tttatgtaaa aaaataaagt taggtataaa tcaatcacct
      121 ataatggctc aagatataaa aataaaatat ccatttgctt ttgaactagc taatatagct
      181 aaaaagacaa tagaaaaaga tttgaagata gaaattaatg aagatgaagt tgcaaacata
      241 gctctacata taggaggagc agttgaaaga gcatcttata ataataaaga taaggttttc
      301 aaaactataa tagtttgtac ttcaggcata ggcacatcaa tgttaataaa agctaaatta
      361 gagaatatat ttaaggaaaa attagaaata ctaaagatta ttccttcata cttagttgaa
      421 tatataaaag ttatagatgt tgattttgta atatctactg ttcctattga agtaggagat
      481 gtgccagtaa taaatatatc tccaatttta agtgagaaag aaattagatt aattgaaaaa
      541 tatatagaaa caggaaatat atacctagat ttagatataa aaagcctgtt tgatagtgaa
      601 ttgtttttta ctgatttggt gtttaaaagg aaagaagaag ttatagattt tatggcaagt
      661 aaacttgtac aaaagggcta tatagatgag gatatgaaaa aatcttactt tgagagagaa
      721 aaaatagcaa caacagaaat agggaatatg gtaactatac cacatggagc tattggaaaa
      781 atttttgata ataaaatagc aattggtata ttaaagaagc ctatttcttg ggaaatatca
      841 gatgttcgtt taataataat gttagccctt gataaagata aaatattaga ttatgaagta
      901 atattttcaa aaatatataa aagagtagat tctatagcaa aagttataag tatatgtgaa
      961 aatagtagtt ttgaaaaatt tgtaaattta tttaattaga tgggtagtat tgtatataca
     1021 cctgtaaatt tggataatat aaaactaaat aagataaaaa cgataaattt ctcttttaat
     1081 taagagaaat tttttgactt tcaaggatat taatataaag ttaagatata aacataaagc
     1141 aaataaataa aaaagaggtg gcaatatgat ttatacagtg acattaaatc catcaataga
     1201 ttatatagtt aagctagatg agctaaagac aggaagtaca aatcgtgtaa aagaagaata
     1261 cgtttatcca ggaggaaaag gtataaatgt atctcgcata cttaaggaac ttggaaatga
     1321 taatacatct ttaggtttta taagtggttt tactggagaa tatataataa gaacattgga
     1381 agaaaaagaa ttgaagacag attttataaa gataaaaagt ggtttttcaa gaataaatgt
     1441 aaaaataaag gcgttaaagg aaactgagat taatggacaa ggtccaaata tagatgatga
     1501 agacattgat actttatata aaaaacttga taagctaaat caagatgata ttttaatatt
     1561 ggcaggaagt ataccatcta ctttagatga aaaactatac gaaaatataa tggctagatt
     1621 agaaaaaaag aatataaaag ttgtagtaga tgcaactaaa aatcttcttc ttaatgtttt
     1681 aaaatacaaa ccttttctaa ttaagcctaa taacgacgaa ttagaagaac tatttggtgt
     1741 taaattaaat tcaattgaag acatggtaaa atatgctaga aggttaaagg aaatgggagc
     1801 tataaatgtc ttggtatcaa tgggaaaaga tggagcattg ttgattacag aggaagatga
     1861 agtgcttata agtgatgttc caaaaggaaa agtaaaaaat tctgtaggag caggtgattc
     1921 aatggtagca ggatttatat ctgggtattt gaatactggg aaatatgatt atgctcttaa
     1981 attgggagca gcttcaggta gtgcaactgc tttttcatat gacttagcca aaagagaata
     2041 cattgataaa ttggtaaatg aaatatctgt aaagaagttt taaaatatta aaaaatatat
     2101 agaaaggtaa ttaatattta tgaaaattat agatttatta gatgaaaagt caattaagtt
     2161 aaatttaaat tcaaaaacca aatcagaagc aatagaagaa ttagtagatt tggtcgcaaa
     2221 tagtggaaat ttaaatgata aagaaaacta caaaaaagca attttggctc gtgaagaaat
     2281 gagtacaaca ggaattggag aaggtgtagc tatacctcat gctaaaaatt cttcagttac
     2341 taaagcttgt atagcagcag cagtgtcaaa agaaggtata gattatgaat cgtttgacgg
     2401 aagtttatca aatctatttt ttatgatagc tgcaccagac ggagctaaca atactcatct
     2461 tgaagtatta tcaagattat ctacaatact tatggatgaa gactttagaa ataaacttat
     2521 aaattcaagc tctgaaaaag aatttaagga aataatagat aaaaaggaaa gagaaaaatt
     2581 cagtgaagaa tatcaagatg agaaagtggc tgaaaaaaat ataatagata ctaaagagaa
     2641 tgatgctaat aagtatccta aggttttagc agtaacagca tgtccaactg gaatagcaca
     2701 tacatttatg gcagctgaaa gtttaaataa aatggcagaa aacaaaggtg tatcaataaa
     2761 agtagaaact aatggttcag caggtgttaa aaataagctt acaaaagatg aaatagaaaa
     2821 tgcaacatgt ataatagtgg cagcagataa aaatgttgag atggctagat ttaatggcaa
     2881 aaaagtcata aaaactaagg tggctgatgg tatacacaaa gcggaagaac ttatagacaa
     2941 ggctgtaaat ggagatgctc caatttacca tggaggagat ggaagtcaca acgaatcaaa
     3001 tgaagaaagt gaaagtggat ttagaaaagt atacaaacac ttaatgaatg gtgtatctaa
     3061 tatgttacca tttgttattg gtggagggat acttatagcg atagcctttt tacttgatga
     3121 ttatactatt aacccttcaa actttggttc aaatacacct atagcagcat tttttaaagg
     3181 aataggagat aaagcttttg gatttatgtt acctgtactt gctggatata tagcatactc
     3241 tatatctgat agaccagcgt ttgttgtagg atttgtagga ggtgctctag caggtgatgg
     3301 tggttcaggc tttttaggtg cactacttgc aggttttata gcaggttatt tagtagaagg
     3361 gcttaagaaa atatttagtg tactaccagc ttcattggaa ggaataaaac cagtattgtt
     3421 atatccttta cttggaacac ttttgatggg aattataatg acatttttag taatacctcc
     3481 agttacagca attaataatg caatggttgg atttttaaat ggtttaggtg gaacttcaaa
     3541 aatagtttta ggattagtat taggtggaat gatggctgtg gatatgggtg gacctgtaaa
     3601 taaagcagca tatgtatttg gagttgcatc acttgaatca gggcagtttg aaataatggc
     3661 agcagtaatg gctggtggta tggttccgcc acttgctata gctcttgcaa ctacattttt
     3721 taagaataga tttactaaag aagaaagaga ttctggtaaa gttaattatg taatgggatt
     3781 atcatttgtt actgaaggag ctataccttt tgcagctgga gacccacttc atgttatacc
     3841 agcttgtgtt ggaggttcag cagtggcagg agcacttagt atgttgttca acgcagctct
     3901 tcgtgcacct catggaggag tatttgttat accagtggtt acccatccat ttgcatatat
     3961 attagctata gctgtaggtg ctttggttgg aatgatgctt ttagcattac ttaaaaaacc
     4021 attaaatcaa gaagtatagc aattaaagga tattcaagaa cttaaaatat gatgttttat
     4081 aaaaattaat atattgctga attattttaa aataaggatt ttatgaggct gttatataac
     4141 gatttgtaat tgttatcttg acagtctttt atttttatat aagtaaaata agtgtgtttt
     4201 gctttatttg tatttaaatt gtttttaagt tagaatataa agaaaattat atattattt
//
LOCUS       DAEPHU010000152         4100 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 01A10CD0081
            SAMN05941466-rid12468953.denovo.154, whole genome shotgun sequence.
ACCESSION   DAEPHU010000152 DAEPHU010000000
VERSION     DAEPHU010000152.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941466
            Sequence Read Archive: SRR6291087
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 4100)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4100)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068158.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 22:43:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,892
            CDSs (total)                      :: 3,805
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 87
            rRNAs                             :: 8, 1, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 55
            CDSs (without protein)            :: 55
            Pseudo Genes (ambiguous residues) :: 0 of 55
            Pseudo Genes (frameshifted)       :: 21 of 55
            Pseudo Genes (incomplete)         :: 28 of 55
            Pseudo Genes (internal stop)      :: 16 of 55
            Pseudo Genes (multiple problems)  :: 8 of 55
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4100
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941466-rid12468953.denovo.154"
                     /strain="01A10CD0081"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            175..960
                     /locus_tag="KR231_003707"
     CDS             175..960
                     /locus_tag="KR231_003707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBH0006030.1"
                     /translation="MIVKIDNTLEKEFWQYVSHEESLNLFIIGYVENYGFSSQYQDIW
                     SQVEDGNITSIILKNKSTLIIYSFKNNFNIGEMKNHIKDLDVESISGKKCVIDRLISK
                     YKDFYEKLDNKFCVLKEIKEIDFSNMKEYKIENAQEKDIDEIGKLLNRSDYKVSKNYI
                     EERKVHLKEGNVRAYFIRNDDTMISTVSTGMETSFLAMVVSVSTDKRYRGKGLASYMV
                     YNLSKELLLEGKVPCLFYNNDVAGKIYHNIGYKEINEWTILFK"
     gene            complement(1057..1881)
                     /gene="pdaA"
                     /locus_tag="KR231_003708"
     CDS             complement(1057..1881)
                     /gene="pdaA"
                     /locus_tag="KR231_003708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="delta-lactam-biosynthetic de-N-acetylase"
                     /protein_id="HBH0006031.1"
                     /translation="MKKDSLKKYIMIGAFALILFGIASINFKSLDKTKTQISSPTLDT
                     HEYDWYFNPREDGKQPSPIKEADFFKKYGAYYVGNPNEKVIYLSFDAGYESGNTPKLL
                     DTLKKHNAKAQFFVVESYIKSNPELIKRMEKEGHLVCNHSKSHPSMAGITDFEKFKEE
                     ITSVEKAYKDVTGKEMPKYFRPPMGKFSEQSLKYTQDLGYKSIFWSFAYVDWYEKKQP
                     THEFAKNKIYSRTHPGAIVLLHPNSSTNTEILDEVLTHWEKEGYKLKTLDYLNNKK"
     gene            2102..>4100
                     /locus_tag="KR231_003709"
     CDS             2102..>4100
                     /locus_tag="KR231_003709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HBH0006032.1"
                     /translation="MDNIISVLNDVVFLDIEVSGLDCLNSEILEVGAVKVKDWKIYTY
                     ESLIKNKFEVPVEVFSVCKNLDKNDLEIANEIELVEDRLVNFVEDSFIICHDLSLKKK
                     FLEYHMPKLKNKFIDLIELAVILEPYHKDYSLEYLKNTLTNCNSKVENRALSDAIDII
                     NIVNCLLVKFNNYEKTTLEPLSFKINSYLKKFNLPTWEWSKFLEEANYDLSNNINIKK
                     EYNIFDSKEEKKKERETLKILNEEEKNYEELLKYKTIWENKEGFTYEYRPGQYELTKT
                     IRELFRNSEDEEKIACIEAPTGIGKSVGYLLPAILEARINKKRLLISTDTKELQIQLI
                     NKDIPNVLDSLGLNGKVSYGYIKGKNNYICIDRLEAYIDDYESQNPTKGEILSLIFLK
                     RLVEGGKYGDIEEINYLVFDNFKEISTHLRNVSCDPNMCRPKKCKKDCLYKNRIEELK
                     EEHITVVNHSLLAKWPYKDEKPLENIIVDEAHNLTEKGYDFFSSIINSKSLRYLLQEI
                     YPYEFIQNSSFIYKKYSRNMRKIKAFDKFYNVLKIGREDKQKIARSINLIIEEIDSIL
                     KFGNCNEYNNVSNYNLRWELNLQIDEIVGKLKKDGIDTEISYRAYSEKIKLSCEKIIK
                     NLVSIIIIIYRNIDDDSIDKEADIYKFGKAKTRDLEDIKIIF"
BASE COUNT         1698 a          365 c          652 g         1385 t
ORIGIN      
        1 agaggtattt cagtagaaga agcttggagt gaagcagtaa cagaatataa aaataaatac
       61 gaacatattg catagatatt taaaaattta gaatatttgg tagaatataa tgattttaaa
      121 tgatactata aattataagg tatatcatta ttaacataga aggaggatat ctgcttgatt
      181 gtaaaaatag ataatacttt agaaaaagaa ttttggcaat atgtatcaca tgaagaaagt
      241 ttaaatttat tcataattgg atacgttgag aattatggat ttagctctca atatcaagat
      301 atatggtctc aggtagaaga tggaaatata acctctataa tattaaaaaa taagtcaaca
      361 cttataattt atagttttaa aaataatttt aatataggag aaatgaagaa tcatataaaa
      421 gatttagatg tagaaagcat aagtggaaaa aaatgtgtaa tagatagact aataagtaaa
      481 tacaaagatt tttatgaaaa actagataat aaattttgtg tattaaaaga aataaaagaa
      541 atagattttt ccaacatgaa ggagtataaa atagaaaatg ctcaggaaaa agatattgat
      601 gaaataggaa aacttttaaa taggtcagac tataaagtaa gtaaaaatta catagaagaa
      661 agaaaagttc atttaaaaga gggaaatgta agagcatatt ttattagaaa tgatgatact
      721 atgattagca ctgtgtcaac tggtatggaa actagttttt tggcaatggt ggtctctgta
      781 agtacagata aaagatatag gggaaaagga cttgcaagtt atatggttta caatttgagt
      841 aaagaattgt tgttagaagg aaaagttcca tgtctttttt ataataatga tgtagcaggt
      901 aaaatatatc ataatatagg atacaaagag ataaatgaat ggacaattct ttttaaatag
      961 ctataaaaaa taaaaaactc tatcgagaat taaagtattt ataaataact atatttttac
     1021 tataattcat gatagagttt ttttaaattt atgatactat tttttattat ttaaataatc
     1081 aagtgtttta agtttataac cttctttttc ccaatgtgta agaacctcat ctaatatctc
     1141 agtatttgtt gatgaatttg gatgcagtaa aactattgca ccaggatgag ttcttgaata
     1201 aattttgttt ttggcaaatt catgagtagg ttgtttcttt tcataccaat ctacataagc
     1261 aaaactccaa aatattgatt tatatcctaa atcttgtgta tattttaaag attgttcgct
     1321 aaatttaccc attggaggtc taaaatactt aggcatttct tttccagtaa catctttgta
     1381 tgctttttct acacttgtaa tttcttcttt gaatttttca aaatctgtaa tacctgccat
     1441 tgatggatgg ctttttgaat gattacaaac taaatgtcct tctttttcca tacgctttat
     1501 taactctgga ttgcttttta tataactttc aactacgaaa aattgagctt tagcattgtg
     1561 ttttttaagc gtatctaata attttggagt gtttccactt tcatatccag catcaaatga
     1621 tagatatata actttttcat tgggatttcc tacataataa gctccgtatt ttttaaaaaa
     1681 atcagcttct tttataggtg atggctgttt accatcctcc ctagggttaa aataccaatc
     1741 atattcatgt gtgtcgagtg ttggactaga aatttgagtt tttgttttat ctaatgattt
     1801 aaaatttata ctagcaattc caaaaagtat tagagcaaat gctcctatca taatgtattt
     1861 ttttaggcta tcttttttca caatttcacc tcttatttaa aatttaaagt atatttctta
     1921 taatatagtt tgaatattta tagttaaaaa tattcacata tacaaataat aaatgaaaga
     1981 agtttactgt aagatataaa gttgatatta attatcttaa ataaagtgta tataaatgat
     2041 aaaatataaa gagaaatgat tgtaaataag ttaggctggt ttaacttgaa gggatataaa
     2101 aatggataat ataataagtg tattgaatga tgttgttttt ttagatatag aagttagtgg
     2161 attagattgt ttaaattcag aaattttaga agttggagct gtcaaggtta aagactggaa
     2221 aatatatacc tatgaatcat taataaaaaa caaatttgag gtacctgtag aagtattctc
     2281 agtatgtaaa aatttagata aaaatgattt agaaatagct aatgaaatag aactggtgga
     2341 agatagactt gtaaattttg tagaagatag tttcattata tgtcatgatt taagtctgaa
     2401 aaaaaagttt cttgagtatc atatgccaaa gttaaaaaac aaatttattg atttaattga
     2461 attagcagtt attttagaac catatcataa agattatagc ttagaatact taaaaaatac
     2521 tttaacaaat tgtaattcta aagtggaaaa tagagcttta tcagatgcta ttgatataat
     2581 aaatattgta aattgccttt tagtaaaatt taataactat gaaaaaacta ctttggagcc
     2641 attgagtttt aaaataaatt catatcttaa aaaatttaat cttccaacat gggaatggag
     2701 caaattttta gaagaggcaa attatgattt atcaaataat ataaatataa aaaaagaata
     2761 taatatattt gactcaaaag aagaaaagaa gaaggaaaga gaaaccttaa aaattttaaa
     2821 tgaagaagaa aaaaattatg aagaattatt aaaatacaaa actatttggg agaataaaga
     2881 aggatttaca tatgaatata gacctggtca atatgagctt actaaaacaa taagagagtt
     2941 gtttagaaat agcgaagatg aagaaaaaat tgcatgtata gaggcaccaa ctggtatagg
     3001 taaaagtgta ggatatttat tgcctgcaat attagaggct agaattaata aaaaaagatt
     3061 attaatttct actgacacaa aggaattgca gatacaatta ataaataaag atattccaaa
     3121 tgtgttagat tctttgggtc taaatggaaa agtaagttac ggatatataa agggaaaaaa
     3181 taactatatt tgtatagata gactggaagc atatatagat gattatgagt ctcaaaaccc
     3241 tactaaagga gaaattttat ctttaatatt tttgaagaga ttagttgaag gtggcaagta
     3301 tggagatata gaagaaataa attatttagt gtttgacaac ttcaaggaaa taagtactca
     3361 cttaagaaat gtaagttgtg acccaaatat gtgcagacct aaaaaatgca aaaaagattg
     3421 tttatataaa aacagaatag aagaattaaa agaagaacat ataacagtag taaatcattc
     3481 actattagct aaatggccat ataaggatga aaaaccttta gaaaatataa tagtagatga
     3541 agcacataat ttgactgaaa aaggatatga tttcttttca agcattataa attcaaagtc
     3601 tttaaggtat ttattacaag aaatttatcc ttacgagttt attcaaaata gtagctttat
     3661 atataaaaaa tatagtagaa atatgagaaa aataaaggct tttgataaat tttataatgt
     3721 attaaaaatt ggaagagaag ataaacaaaa aattgctaga agtataaatc tcattattga
     3781 agagatagat tcaatattaa agtttggtaa ttgtaatgaa tataataatg taagtaatta
     3841 taatttaaga tgggaactga atttgcaaat agacgaaatt gtgggaaaac taaaaaagga
     3901 tggtatagat actgaaataa gttatagagc ctatagtgaa aagataaagt tgagttgtga
     3961 gaaaataata aaaaatttag tttcaataat aataataatt tataggaata ttgatgatga
     4021 tagtatagat aaagaagcag atatatataa atttggaaag gcaaagacaa gagatttaga
     4081 ggatataaag attatatttg
//
LOCUS       DAEPHU010000153         3920 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 01A10CD0081
            SAMN05941466-rid12468953.denovo.156, whole genome shotgun sequence.
ACCESSION   DAEPHU010000153 DAEPHU010000000
VERSION     DAEPHU010000153.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941466
            Sequence Read Archive: SRR6291087
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 3920)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3920)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068158.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 22:43:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,892
            CDSs (total)                      :: 3,805
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 87
            rRNAs                             :: 8, 1, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 55
            CDSs (without protein)            :: 55
            Pseudo Genes (ambiguous residues) :: 0 of 55
            Pseudo Genes (frameshifted)       :: 21 of 55
            Pseudo Genes (incomplete)         :: 28 of 55
            Pseudo Genes (internal stop)      :: 16 of 55
            Pseudo Genes (multiple problems)  :: 8 of 55
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3920
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941466-rid12468953.denovo.156"
                     /strain="01A10CD0081"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            complement(<1..348)
                     /locus_tag="KR231_003710"
     CDS             complement(<1..348)
                     /locus_tag="KR231_003710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBH0006033.1"
                     /translation="MIRLTIANIKRYLKNHNLLINMVMLPIILIFSLNFFINNSGNQS
                     MYFSPVAIVSDSSGKYEHKLINSSKLKENSFRLNELDKAMNLLKNNKVSAVFVLDKNF
                     SNSIDKLQRPVVKC"
     gene            complement(351..1448)
                     /locus_tag="KR231_003711"
     CDS             complement(351..1448)
                     /locus_tag="KR231_003711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBH0006034.1"
                     /translation="MKLYMSVKTMLKSLKSSFILNLIYFLALPLILSWFLGMVTESMF
                     QNPIKTESTPIVIYDKDNTRLSNDLTKYLKNDLSYILTVKKDDSKAELKLTIPKGYES
                     SLLNEKSNTLNIEKLGTRDDIAILLQDILDTYHEKFYLNNSQKISSEDFSKLFNKNSI
                     DTSIINNNVKQNSYEYFALVSLGFLVIIFIMNNILSNYISESKGLSKRLYSMPITRVQ
                     FLIYDFVGLWIYSFIFLLLYVLFFRILGITFKGNFAILLLLCALSSYFMTSISTFVTS
                     FFSKKYGTAIVYALLFLQTIFGGIFSMISDTFTKLTSLSPTYLIGELFSNYETFKTID
                     SIGDLIFTCLIISTILIALAIVKEKYKWREV"
     gene            complement(1462..2397)
                     /locus_tag="KR231_003712"
     CDS             complement(1462..2397)
                     /locus_tag="KR231_003712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH0006035.1"
                     /translation="MDIVRVNNITKRFNDKLVLDNISFSVKKGEIFGLIGPNGAGKST
                     LINIITNLMLPNSGSIQINGLDLSKDYIKAKSIIGLVPQELAIIETLTPFDNLEYFGA
                     FYGLKGKLLKERIIEALEVTGLTEVKKKKVKKLSGGMQRRLNIGIALLNHPKILILDE
                     PTVGVDPQSRNHIFNFIKDISKKHETTVIYTSHYMEEVEHLCSKIFIMDEGKEIAFGD
                     NDYLKSLVSTNTKLIIEIKNINAQLIFDLKNTKGVISVLENNSLLELDIDKKLQLTDI
                     LSVIDKNNSKIMKISYEEPSLEDVFLNLTGKNLRD"
     gene            complement(2526..3173)
                     /locus_tag="KR231_003713"
     CDS             complement(2526..3173)
                     /locus_tag="KR231_003713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBH0006036.1"
                     /translation="MNKIKVLIVDDEKLIRKGLKIILSSYNDLEIVGDASNGYEALEF
                     CKMNDVDIVLMDIRMKVCDGVLGTRLIKEYNNSITLLILTTFNDDEYIKDAMKFGASG
                     YLLKDSSDEVLHEGIRSSFFGNIVLDKSVAEKIMTSEKTVKQEHLYDMYNLTEKEISI
                     IRLIANGLNNKEISQELFLSEGTIKNNITNILAKLELRDRTQLAIFAFKNKIVIE"
     gene            complement(3166..>3920)
                     /locus_tag="KR231_003714"
     CDS             complement(3166..>3920)
                     /locus_tag="KR231_003714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HBH0006037.1"
                     /translation="LSIYIENENLSKLYSQNLYDKLRISKDELKKVNADLETYASSIE
                     ELAILKERNRISREIHDSVGHSLSTTIIQLNAIEKLLKDKPLIYDLVHELREFVTESF
                     QDVRRAISELKPVEYENYQSLFKIKELVKSFIKLTNINVKLTISKNTWNLSRNQSITL
                     YRLIQESLSNSSRHGKATEIRIFITFNTSNLIITISDNGIGCGNIKKGNGLNSINERI
                     YELNGKVEFDNSNNGFTIRASFPKFSGGDFFE"
BASE COUNT         1374 a          540 c          448 g         1558 t
ORIGIN      
        1 gcatttaact acaggtcgtt gtaatttatc tatactattt gaaaaatttt tatctaaaac
       61 gaatacagca gaaaccttat tattttttaa tagattcata gccttatcta gttcatttaa
      121 tctaaatgaa ttttctttta atttagaact atttattaac ttatgttcat actttcctga
      181 agagtcagat acaattgcta ctggagaaaa gtacattgat tgatttcctg agttgttgat
      241 aaaaaaatta agtgaaaaaa ttagtataat aggaagcata accatattaa ttaaaagatt
      301 atgatttttt agatatcttt ttatatttgc aatagttaat ctaatcatta ttaaacctcc
      361 ctccatttat atttttcctt tacaatagca agtgcaatta atattgtaga gataattaaa
      421 catgtgaaaa ttaaatctcc tattgaatct atagttttaa atgtttcata attactaaac
      481 aattctccta ttaaataggt aggagataaa cttgtaagct tagtaaatgt atcacttatc
      541 atactgaaga tacctccaaa aattgtctgt aaaaagagta atgcataaac tattgctgta
      601 ccgtattttt tactaaaaaa gctggttaca aaggtagata ttgaagtcat aaaataagat
      661 gataaagcac aaagtaggag caatatggca aaattacctt taaatgttat tccaagtatt
      721 ctaaagaata aaacatataa taataagaat ataaatgaat aaatccataa acctacaaag
      781 tcataaatta agaattgtac tctagttata ggcatagaat aaagtctttt tgaaagtccc
      841 tttgattcac ttatataatt tgacaaaata ttgttcatta taaaaattat tacaagaaat
      901 cctagtgaaa ctaaagcaaa gtattcataa gagttctgtt taacattgtt atttattata
      961 gaagtatcaa tagaattttt attaaataat ttagaaaaat cttctgaact tattttctga
     1021 gaattattta aataaaattt ttcatggtaa gtatctaata tatcttgaag caatattgca
     1081 atatcatcac gagttccaag tttttctatg tttagagtat ttgatttttc atttaataaa
     1141 ctactctcat agcctttagg tatagtaagc tttaattctg ccttagaatc atctttttta
     1201 actgttaata tataagataa atcatttttc aaatactttg tcaaatcatt tgataatctt
     1261 gtgttatctt tgtcatatat aacaatgggg gtagattctg tttttatagg gttttgaaac
     1321 atgctttctg taaccatccc aagaaaccaa gataaaatca gaggcaaagc taaaaaatat
     1381 attaaattaa gtataaagga gctttttaaa ctctttagca tagtttttac actcatgtat
     1441 aatttcataa aatcacctcc attagtccct taaatttttt cctgttagat ttaaaaatac
     1501 gtcttctagg ctaggttctt cataagaaat tttcattatt tttgaattgt ttttgtcaat
     1561 aacagagagt atatctgtaa gttgtaattt tttatctata tccaattcta ataatgaatt
     1621 attttctaaa acagatataa cacctttagt attttttaaa tcaaagataa gttgggcatt
     1681 tatatttttt atttctataa ttaattttgt atttgtagat acgagtgatt ttaaataatc
     1741 attatctcca aaagcaattt ctttaccttc atccataata aaaattttag aacaaaggtg
     1801 ttcaacttct tccatataat gggaagtata tattacagta gtttcatgtt ttttagatat
     1861 atcttttata aaattgaaaa tatgatttct tgattggggg tctacaccta cagttggttc
     1921 atccaatatt aatattttag gatgatttaa gagtgctatt ccaatattta atctcctttg
     1981 cataccacca gataattttt tgaccttttt ctttttgact tcagtaagac ctgtaacttc
     2041 taatgcttca atgattcttt ctttaagtag ttttcccttt aaaccgtaga aagctccaaa
     2101 gtactctaag ttatcaaaag gagtaagagt ttctataatt gctaattctt gtggaactaa
     2161 ccctattata gactttgctt ttatataatc ttttgataaa tctaaaccat tgatttgaat
     2221 actaccacta tttggtaaca taagatttgt aattatattt ataagtgtag atttacctgc
     2281 accatttggg ccaataagtc caaatatctc acctttttta acagaaaagc tgatgttatc
     2341 aagtactaat ttatcattaa atctttttgt tatattattt actctgacta tatccatagt
     2401 aatccctcca aaataatttt gtataagtta aaaagctata atattataat aaagaattgt
     2461 gaattataat tctattacta taagtcacta aaaaaagtga cttaagtcac tttatatttt
     2521 tagatttatt ctattacaat tttatttttg aaagcaaaga ttgctagttg agttctgtca
     2581 cgaagttcta gtttagctaa aatattagtt atattattct ttattgtacc ttcagataag
     2641 aatagttctt gacttatttc tttattatta agtccatttg caattagtct aattatagat
     2701 atttcttttt ctgttaaatt gtacatgtca taaagatgct cttgtttaac cgttttttca
     2761 gaggtcatga ttttttcagc tacactttta tcaagcacaa tattgccaaa aaatgaagaa
     2821 cgaatccctt catgcaatac ttcatcagag ctatctttta aaaggtatcc tgaagcacca
     2881 aacttcatag catcttttat atattcatca tcattaaaag ttgttaaaat taataatgtt
     2941 atagaattat tatattcctt tataagcctt gtacctagaa ccccatcaca tactttcatt
     3001 cgtatatcca taagaactat gtctacatca ttcattttac aaaattctaa agcttcatat
     3061 ccattagaag catctcctac aatttctaaa tcattataag atgataatat aattttaaga
     3121 ccttttctaa ttaatttttc gtcatctact ataagaactt taattttatt caaaaaaatc
     3181 accccctgaa aatttaggaa aagaagctct aattgtgaaa ccattattag aattatcaaa
     3241 ttcaacttta ccatttaatt catatattct ctcattgata ctattaagtc catttccttt
     3301 ttttatattg ccacatccta taccattatc actaatagta attataagat ttgaagtatt
     3361 gaatgtaata aaaattctga tttcagttgc ctttccatgc ctagatgagt tggaaaggga
     3421 ttcctgtata agtctatata aagttataga ttgatttctg gataagttcc aagtattttt
     3481 tgaaatagtt aatttaacat taatatttgt aagcttaata aagcttttaa ctaattcttt
     3541 gattttaaat aaactttggt aattttcata ttcaacaggt tttaactcag atatagccct
     3601 tcttacatct tgaaaacttt cagttacaaa ttctctaagt tcatgtacta agtcataaat
     3661 tagaggtttg tcttttaaga gtttttctat agcatttaat tgtattattg ttgtagaaag
     3721 agaatgtcct acactatcat gtatttctct tgatattcga tttctttctt ttaaaattgc
     3781 taattcttct atagaacttg cataagtttc caaatcagca ttaacttttt ttaattcatc
     3841 tttagaaatt ctaagcttat cataaagatt ttgactgtat aattttgata aattctcatt
     3901 ttctatatat atagaaagta
//
LOCUS       DAEPHU010000154         3904 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 01A10CD0081
            SAMN05941466-rid12468953.denovo.157, whole genome shotgun sequence.
ACCESSION   DAEPHU010000154 DAEPHU010000000
VERSION     DAEPHU010000154.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941466
            Sequence Read Archive: SRR6291087
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 3904)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3904)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068158.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 22:43:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,892
            CDSs (total)                      :: 3,805
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 87
            rRNAs                             :: 8, 1, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 55
            CDSs (without protein)            :: 55
            Pseudo Genes (ambiguous residues) :: 0 of 55
            Pseudo Genes (frameshifted)       :: 21 of 55
            Pseudo Genes (incomplete)         :: 28 of 55
            Pseudo Genes (internal stop)      :: 16 of 55
            Pseudo Genes (multiple problems)  :: 8 of 55
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3904
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941466-rid12468953.denovo.157"
                     /strain="01A10CD0081"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     repeat_region   104..927
                     /inference="COORDINATES: alignment:crt:1.2"
                     /inference="COORDINATES: alignment:pilercr:v1.02"
                     /rpt_family="CRISPR"
                     /rpt_type=direct
                     /rpt_unit_range=171..199
                     /rpt_unit_seq="atttacattccatatagttaatataaaac"
     gene            complement(1586..3679)
                     /locus_tag="KR231_003715"
     CDS             complement(1586..3679)
                     /locus_tag="KR231_003715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EAL domain-containing protein"
                     /protein_id="HBH0006038.1"
                     /translation="MNKHNFEVILNQLQINIYVTNIHTNEIIFMNKKMKEEYNILDPE
                     GKVCWQVLYPEKNSTCSFCKVLELLKNDKKGVLIKWYEKCNKLNRVFENYDSLITWQD
                     GTVVHMHQSIDIANSTSLNKPIKINEFHEISNNKEEKGVFNFSRDNFDYNSTLLYDAL
                     IRGTDEYIYICNMKTGVFRYSPSQVELFDLPGEIVENPLVYWKKIVHPEDWNRFYKSN
                     TEIGKNQMDYHTVEFRAKNRSGEYIWLRCRGQLMRDEFGEPSIFAGIMTQLGKQNKID
                     SLTQLLNYHEFMSVFEDKISNPMIEKLCIVLLDIDDFKNVNEMYDRDFGDNIIKTLAQ
                     SIQSILPDNAELYKLDGDEMGILVDNVEENEILTLYNQIQNMIIHLQLWRKYGLNITI
                     SAGCVIYPKHGDTVKELYKCASYSLQYAKEHGKNRLVFFSQEILKNKMYSLEMMRDLK
                     ASINDDFRGFSLRFQPQVDTESHKIIGVEVLLRWTNDKCKAISPLEFIPILEENDMIN
                     IVGAWVLRMALRTFRKWIDYYPFFKVSVNVSAVQILEDTFIEDIVKIIDDENFPYQNL
                     VLELTESHTVQNMSILQFKFKALQDLGIYIAMDDFGTGYSSLEVLKFSPIDIVKIDRV
                     FVKDILKSKFDATFIHFIVAICHDVGIKVCLEGVETQEEYDLVKQIKPDYIQGYLFGK
                     PQTATEIFDLLKLDN"
BASE COUNT         1390 a          601 c          370 g         1543 t
ORIGIN      
        1 aggatttcta tactaccttt ttgtttttat aatatagtgt aattttatta tatttttgta
       61 tgctaatata actagataat cataagataa cacattaaaa gaaaattata ttctgtatag
      121 ttagtataaa acgtaagtaa tataaattta tgtaaagcaa caaaagatgg atttacattc
      181 catatagtta atataaaacg atttcaaatg attagaataa aaatatcaga attgctattt
      241 atattccata tagttaatat aaaactataa agtgttactt ttatttattt tattttttac
      301 ataatttaca ttccatatag ttaatataaa acgcattata tggctgtgtc attttgcatt
      361 ctattacata tttacattcc atatagttaa tataaaacct gcttaatgca gaattaagag
      421 aggaagtgtt ataagattta cattccatat agttaatata aaactggttg ttcctgctcc
      481 ggtgttggtg gaactggtac atttacattc catatagtta atataaaacg aatatgtatg
      541 gataattttt tacttaacat attagcattt acattccata tagttaatat aaaacctgct
      601 gtaatttctg atgaagcttc tccactacca ccatttacat tccatatagt taatataaaa
      661 cccttcttta actcttatcg tatttaaacc tcttataaca tttacattcc atatagttaa
      721 tataaaactt tttgtgttaa gaagaaaaaa gaaattttga taatatttac attccatata
      781 gttaatataa aaccttaaag aaaaaatgga ggaagattaa gtgaaaaaat tatttacatt
      841 ccatatagtt aatataaaac tggatttaaa taatcaaaac aactccggtt taaaaaacat
      901 ttacattcca tatagttaat ataaaacccc aaaataaact tagtattttc aacacttaca
      961 cgtatacaac tctcttaaat ttgcagtgaa cgagcaatag tgcaattgat aacgcttatc
     1021 atacactctc aacgccttat atttcaactg ttacgccaaa ttttttcaca aatatcgctc
     1081 actgcaaaat tcctataatt ttattatatc ataaatatat tacttttgaa tattgatacc
     1141 aatttatacc ataataaaag caaaaaaacg taatctatct acattagatt taaattctat
     1201 aacttaaagt tttttacata atatttatgc ttgtttaatc aatctaatat atcattcttg
     1261 tatattgctt ttaatagtct tttttcttaa ataaatatct atctgaacaa gcatagttta
     1321 attaaaaact tttgtattcc cttaaaactg tatctacctc ttattatttt atttatgata
     1381 tattattttt aatctaaaaa tagatatcta tttttattat ggttatccct ttttaaaata
     1441 ctttaatcat atactattcc caatttaaca tccattgaaa tgctattttc ttatattgca
     1501 atttataatt gatatatctt caatataata atttaatgta tttttgattt taaagctttt
     1561 cagtgatatt attgataaat tagaattaat tatctagctt taaaaggtca aagatttctg
     1621 ttgctgtctg cggttttcca aataaatatc cttgtatgta atctggcttt atttgtttaa
     1681 ctaaatcata ctcttcttgt gtttctacac cttctaaaca tacttttatt cctacatcat
     1741 gacaaattgc aacaataaaa tgtataaatg tagcatcaaa cttactcttt aatatatctt
     1801 taacaaatac tctatcaatt ttcactatat ctattggaga aaattttaaa acttctagag
     1861 acgagtatcc agtaccaaaa tcatccatag caatataaat tcctaaatct tgtaaagcct
     1921 taaatttaaa ctgtaaaata ctcatatttt gtactgtatg actttctgtc aattctaaaa
     1981 caagattttg ataaggaaaa ttttcatcat ctataatttt tactatatct tcaataaatg
     2041 tgtcttctaa tatttgaaca gctgaaacgt ttacactcac tttaaaaaaa ggatagtaat
     2101 caatccattt cctaaaagta cgtaatgcca ttcgaagcac ccaagcccct acaatattta
     2161 tcatatcatt ttcttctaat attggaataa attccaaagg agaaattgct ttgcatttgt
     2221 cattagtcca ccttaaaaga acttctacac ctattatttt atgactttct gtatctactt
     2281 gtggctggaa tcgaagacta aaccccctaa aatcatcatt aattgatgcc tttaaatccc
     2341 gcatcatttc taatgaatac attttatttt ttaatatttc ttgggagaaa aaaacaagcc
     2401 tgtttttacc atgctctttc gcatattgta aagagtaact agcacactta taaagttctt
     2461 ttactgtatc tccatgtttt ggatatatta cacaaccagc agaaattgtt atatttaatc
     2521 catattttct ccatagttga aggtgtataa tcatattctg tatttgatta tatagagtta
     2581 gaatttcatt ttcttcaaca ttatcaacaa gaatgcccat ttcgtcccca tcaagtttat
     2641 aaagttcagc attatctggt aaaatagatt gtatagactg tgctagtgtt tttattatat
     2701 tatctccaaa atccctatca tacatctcat taacattttt aaaatcgtca atatctaata
     2761 atactatgca taatttttca atcataggat ttgaaatttt atcttcaaat acactcataa
     2821 attcatgata attcagtaac tgtgtcaatg aatcaatctt attttgttta cctaattgcg
     2881 tcattattcc tgcaaaaata cttggttctc caaattcatc acgcattagt tgacctctac
     2941 atcttaacca tatatattct ccactacgat ttttagccct aaattccact gtatgataat
     3001 ccatctggtt tttacctatt tcagtgtttg acttataaaa acgattccag tcttctggat
     3061 gtacaatttt tttccagtaa acaagcggat tttcaacaat ttctcctggt aagtcaaata
     3121 attcaacttg tgatggtgaa tatcgaaata cgcctgtttt catattgcaa atgtatatat
     3181 attcatctgt acctctaatc aaagcatcat aaagcaatgt agaattataa tcaaaattgt
     3241 ctcttgaaaa attaaaaact cctttttctt ctttattatt tgatatttca tgaaattcat
     3301 taatcttaat tggtttattt aagcttgttg agtttgcaat atctattgat tgatgcatat
     3361 gaacaactgt gccatcttgc catgtaatta aactatcata attttcaaaa acacgattta
     3421 acttattaca tttttcatac cactttatta atactccttt tttatcattc tttaataatt
     3481 ctaaaacttt acaaaaacta caagtagaat ttttttcagg atataatact tgccaacaaa
     3541 cttttccttc tggatctaaa atattatatt cttctttcat ttttttgttc ataaaaataa
     3601 tttcattagt atgaatattt gtaacatata tattaatctg tagttgattt aatataactt
     3661 caaaattatg tttgttcata tacttatctc ctccatagtt actgctcttt ataacaacat
     3721 tgttaaaatt attcttttta gaagatttac ttataactta tacatataca ctaaatacct
     3781 taatttaatt agaaagttta ttacttcata ttttaaatta taattgataa aaaaaaatac
     3841 agcaatatag tattaccaat ttaaaaaaaa ttaatattac ataatacatc tctctcttat
     3901 atta
//
LOCUS       DAEPHU010000155         3901 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 01A10CD0081
            SAMN05941466-rid12468953.denovo.158, whole genome shotgun sequence.
ACCESSION   DAEPHU010000155 DAEPHU010000000
VERSION     DAEPHU010000155.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941466
            Sequence Read Archive: SRR6291087
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 3901)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3901)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068158.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 22:43:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,892
            CDSs (total)                      :: 3,805
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 87
            rRNAs                             :: 8, 1, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 55
            CDSs (without protein)            :: 55
            Pseudo Genes (ambiguous residues) :: 0 of 55
            Pseudo Genes (frameshifted)       :: 21 of 55
            Pseudo Genes (incomplete)         :: 28 of 55
            Pseudo Genes (internal stop)      :: 16 of 55
            Pseudo Genes (multiple problems)  :: 8 of 55
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3901
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941466-rid12468953.denovo.158"
                     /strain="01A10CD0081"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            complement(<1..1820)
                     /locus_tag="KR231_003716"
     CDS             complement(<1..1820)
                     /locus_tag="KR231_003716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tape measure protein"
                     /protein_id="HBH0006039.1"
                     /translation="MATIQTSIKIFDGMTPAFRNMTNSINTTINSLERLQGRLNNPLN
                     AGNIQASQQSLNNIESILTRIEQKIGRNTNEQENFNNKIRQGSEAGSLLVSKLKSIAG
                     IYIGIKGIDSITKVADTIASTKARLNLMNDGLQTTDQLNKMIYLSAQSARASYADTAA
                     QIAKLGILAGDAFGSSAEVIKFTELMNKAFVIGGTSANEASAAMYQLTQAMGAGKLQG
                     DEFRSIMENAPLLATKIADAMGKTKDQLKELSSSGAITADVIRNALFKASDEIEKKFA
                     SMAITFSQALTMMKNDAYMIFSETLSKISGALQSVRFSEIVVSIRNVMIAISSNIYDT
                     LNIIKNILNSDFFSDFVSNVTLGAILIINGLGWVTNATLNVANVFAQNWSIIAPIIYG
                     VIAAIAIYKGVLLASTIATTVASFVNSLYAVAAYKSCAALAAQEFAIFGKISAQTMEA
                     LVTAQATAAQWGFNAALLSCPIFWIIAGIIAFVVVVFVAVAAVNKFSGTSLTVLGAIV
                     GAVFAAVAFIQNIMIWLFNRCVDVNEGIANGWNQCVYLMKQAIAKGVIFIIEKMASLN
                     DAVNNAGNALGKAFIDGANIAIRGVNKLIDLINKIPGINIG"
     gene            complement(1885..2400)
                     /locus_tag="KR231_003717"
     CDS             complement(1885..2400)
                     /locus_tag="KR231_003717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ribbon domain-containing protein"
                     /protein_id="HBH0006040.1"
                     /translation="MFCSNCGYEITGAGKFCSNCGTATLADKVNNDDLFINVHGKELN
                     LTNIYKETKGDKILAIDIAMKLLGLDIKECKNIIYPAFKELSEKINIEEEKEILREDE
                     YKQTNVLEDDVARCPRCGSVSLSAHKKGFGIGKAVAGATIAGGIGLVAGNLGAKKVRV
                     TCLSCGKQFWA"
     repeat_region   2530..3481
                     /inference="COORDINATES: alignment:crt:1.2"
                     /inference="COORDINATES: alignment:pilercr:v1.02"
                     /rpt_family="CRISPR"
                     /rpt_type=direct
                     /rpt_unit_range=2728..2756
                     /rpt_unit_seq="atttacataccacatagttaatataaaac"
BASE COUNT         1301 a          746 c          447 g         1407 t
ORIGIN      
        1 ccaatattta tccctggtat tttatttatt aggtcaatta atttgtttac acctcgtatt
       61 gcgatatttg ccccatctat gaaagctttc ccaagtgcat ttccagcatt atttacagca
      121 tcatttaatg atgccatttt ctcaattata aagattacac cttttgcaat agcttgtttc
      181 attagatata cacattgatt ccatccattt gcaatccctt catttacatc tacgcatcta
      241 ttaaatagcc atatcattat gttttgtata aatgctactg ctgcaaatac tgcacctaca
      301 attgctccta gtacagtcag acttgttcct gagaatttgt ttactgctgc tactgcaaca
      361 aaaactacta ctacaaatgc tataatacct gctattatcc aaaaaattgg acaggataat
      421 aatgctgcat taaaacccca ttgtgctgct gttgcttgtg ctgttaccaa agcttccatc
      481 gtttgtgcag atatttttcc aaatatcgca aattcttgtg ctgctaaagc tgcacaagat
      541 ttatacgctg ctactgcata caatgaattt acaaaagatg ctaccgtagt ggcaattgta
      601 cttgcaagta atactccttt atatatcgca attgctgcta tcactccata aataatagga
      661 gcaataatcg accaattttg agcaaagaca ttagcaacat ttagtgttgc attagtaacc
      721 catcccagtc cattgataat tagtatagct cctaatgtaa cattgctaac aaaatctgaa
      781 aaaaaatcac tatttaatat attttttata atatttaatg tatcataaat gtttgaagat
      841 attgcaatca taacattccg gatagataca acaatctcac taaaacgtac actttgcaaa
      901 gctccactta tcttactgag agtctcagaa aatatcatat aagcatcatt tttcatcatt
      961 gtgagagctt gagaaaaagt gattgccata cttgcaaatt tcttttctat ctcatcagaa
     1021 gctttaaaca gtgcatttct tataacatct gctgttattg ctccgctact tgataattcc
     1081 ttcaattggt ctttagtttt tcccattgca tcagctattt tagtggctaa taaaggtgca
     1141 ttttccatta tggaacggaa ctcatcacct tgaagttttc ctgcacccat ggcttgtgtt
     1201 aattgataca ttgctgcact agcttcattt gctgatgttc ctccaattac aaaagcttta
     1261 ttcataagtt ctgtaaactt tatcacctct gctgaacttc caaaagcatc tcctgcaagt
     1321 attccaagtt tagcaatctg tgctgctgta tctgcataac tagctcttgc actttgggct
     1381 gacaaataaa tcattttatt aagctggtct gttgtctgta agccatcatt cattagattt
     1441 aaacgtgctt ttgtacttgc aattgtatct gctacttttg taatactatc tattcctttt
     1501 attccaatgt atatcccagc aatacttttt aatttagaca ctaatagaga acctgcttca
     1561 ctaccttgtc ttattttatt attaaagttt tcctgttcat ttgtatttct tccaattttc
     1621 tgttctatcc ttgtgagaat actttctatg ttattcaaac tttgttgaga agcttgtata
     1681 ttacctgcat tgagtggatt attcaatctg ccttgcaatc tctctaaact attaattgtt
     1741 gtattaatag aattagtcat attacgaaat gctggtgtca ttccgtcgaa aatctttatt
     1801 gaagtttgta ttgtagccat ttcctcactc tcctttcata aatttccata taaaaaaaca
     1861 cctacattag taagtgttta ttatttatgc ccaaaactgt ttaccacagc tcaaacatgt
     1921 aactctaact ttctttgctc ctaaatttcc agctactaaa ccaatgcctc ctgctatagt
     1981 agcccctgct acagcttttc ctatgccaaa acctttctta tgagcagaca atgaaacaga
     2041 gccacaccta gggcaacgag caacatcatc ttcaagtaca ttagtttgtt tatactcatc
     2101 ttccctcaat atctcttttt cctcttcgat atttattttt tcacttaatt ctttaaaagc
     2161 tggatatata atatttttac actcttttat gtccagccct agtaacttca ttgcaatatc
     2221 aattgctaag attttatctc ctttagtttc tttataaata ttagtcagat ttaattcttt
     2281 tccatgaaca tttataaata aatcatcatt gttaacttta tctgctaatg tagctgttcc
     2341 gcaatttgag caaaatttgc ctgcaccagt tatctcataa ccacaatttg aacaaaacac
     2401 aacaatcacc tcacataata cttattttat agcactatta tactatatac gtaaaatttt
     2461 tacattatta tcacctcctt tcattaaaaa aacacttact catttgtaag tgtttttgaa
     2521 ttatttttaa ttttaagtcc acatagttaa tataaaattg tttgctcaga tgcttttaaa
     2581 tactcaaaca ttagccttta cataccactt agttaatata aaccaaacca atgcacaatt
     2641 tgaaaaaatg ccttttacac tatttacata ccacttagtt aatataaaac gcgttaatgc
     2701 agtaccataa cgatatggga ctaactaatt tacataccac atagttaata taaaacagta
     2761 ttcagaactt gaaaaaaaag ttggaaatag cacatttaca taccacatag ttaatataaa
     2821 accgtatagg aatgaatgca ggtagtgcat tttctagtac atttacatac cacatagtta
     2881 atataaaaca agtagcagga gaagctaaga taaaagttga acgaaattta cataccacat
     2941 agttaatata aaacttgcag ataatactct aagacttgaa gttaaatgtg catttacata
     3001 ccacatagtt aatataaaac cattagaaga atataacata gtagaagatg cagaaaaatt
     3061 tacataccac atagttaata taaaacacca gaaaaggaag gtggcgatat tcttataaca
     3121 aaatttacat accacatagt taatataaaa ccgatatcca tttctccttt tccagtaata
     3181 ttaaatttat ttacatacca catagttaat ataaaacccc aatcatacga accaggaaca
     3241 tatggcaaac tataatttac ataccacata gttaatataa aacaaagact atatcctatg
     3301 ttcataattg ggagtaatac atttacatac cacatagtta atataaaaca attagatgct
     3361 tttgttaaag aacatgcagt tttcaaattt acataccaca tagttaatat aaaacaattt
     3421 tagtattgta attgacgtgc ttttttaaaa agatttacat accacatagt taatataaaa
     3481 ccccaaaata aattgtgtat ttccaagact tacacacata taactttctc aaatttgcag
     3541 tgagcgggta atagtgcaat tgataacact tatcaaacct tctcaatgcc ttgtattcca
     3601 attgttaaac tatacttaag tagaaaaatc gaacactgca aaattcctat atttttatta
     3661 taccatttta taccaaataa agcacttgaa acaacataat atccaagtgc tttatctatt
     3721 tatttaatta tttttctcta attttttctc agaaagttta tatactattc tttctatctt
     3781 attatatata tatatctata tctgtttctc ttattttcaa aagtttaatt ctaaattctt
     3841 cttttctctt ttcaatatct atactatcaa gtaaattctc atacattgta ttaccccccc
     3901 a
//
LOCUS       DAEPHU010000156         3829 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 01A10CD0081
            SAMN05941466-rid12468953.denovo.159, whole genome shotgun sequence.
ACCESSION   DAEPHU010000156 DAEPHU010000000
VERSION     DAEPHU010000156.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941466
            Sequence Read Archive: SRR6291087
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 3829)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3829)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068158.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 22:43:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,892
            CDSs (total)                      :: 3,805
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 87
            rRNAs                             :: 8, 1, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 55
            CDSs (without protein)            :: 55
            Pseudo Genes (ambiguous residues) :: 0 of 55
            Pseudo Genes (frameshifted)       :: 21 of 55
            Pseudo Genes (incomplete)         :: 28 of 55
            Pseudo Genes (internal stop)      :: 16 of 55
            Pseudo Genes (multiple problems)  :: 8 of 55
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3829
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941466-rid12468953.denovo.159"
                     /strain="01A10CD0081"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            complement(89..328)
                     /locus_tag="KR231_003718"
     CDS             complement(89..328)
                     /locus_tag="KR231_003718"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0006041.1"
                     /translation="MECYLKRTLIIFSEAFLSISFKTRKYLFIVIFILVCPNLSEMIF
                     ILVPARRRIIRIDNIVSIYKYVGVLKLINYSILIL"
     gene            540..1811
                     /locus_tag="KR231_003719"
     CDS             540..1811
                     /locus_tag="KR231_003719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase family protein"
                     /protein_id="HBH0006042.1"
                     /translation="MLKVLKGNIIFTKTSETFTVFENSYIILEKGKVKGIFKEIPKEY
                     KNLKVVDYTDKLIIPGMNDLHAHASQFKNLGMAMDKELLPWLETYTFPEESNYKDIEY
                     ATKMYKKFVKELWKSGTTRIAVFATVHKEASMKLMDIFKEVGLGAYVGKVNMNMNCPD
                     TLLENTQDSITDTEEIINKYSDTDSIVKPIITPRFIPSCTSELLKGLGDLCLKYNIPI
                     QSHLSENYDEIEWVRSLEPESKFYGDAYNRYNLFGQTPTLMAHCVHCSQDEIDLMREN
                     NVMAVHCPASNFNVGSGAMPIRKLIDNNIRLALGSDISGGHTLSIFKAMVSAIQLSKL
                     YWVNSGKKYNFLSLSEAFYIATKSGGSFFGKVGSFEEGYDFDALIIDDSNLNHDNYSI
                     LERLERFIYVGDDRNIIHRYVCGKLIEEPNI"
     gene            complement(2451..3206)
                     /locus_tag="KR231_003720"
     CDS             complement(2451..3206)
                     /locus_tag="KR231_003720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1835 domain-containing protein"
                     /protein_id="HBH0006043.1"
                     /translation="MAHICFEDICYLLLKEAMKLKLIPHNKIVLFEDDLSIGNIFDVN
                     NYELRENIFKIRNVFENNPKLLFKPDLLEDRKLSKCRNIIIWCANNPKDLCGVYYVVS
                     KFQDKNIKIALVDEKKTEDALIRYSFTSEMSPEDFPFFLDKTLEIGFNEKLEFKNKWD
                     VLVKENSIFRALVGNEIKSVEETYFDKYILRNISDKWQPLIEVVANCMFEDEMRVKDW
                     FILWRLEKMASLKIVKIKGSKGDFYSDKEIRKV"
     gene            complement(3382..>3829)
                     /locus_tag="KR231_003721"
     CDS             complement(3382..>3829)
                     /locus_tag="KR231_003721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HBH0006044.1"
                     /translation="IGSLNRNKARLKVARLQEHIANQRKDFLQKLSTKLIKENDIICI
                     EDLQVKNMIKNHKLSRSISDVSWSEFIRQLEYKANWHGRQIVKVGKFFASSQICNKCG
                     YKNEEVKNLNIREWICPSCNETHDRDINASINILKEGLRLITIQNK"
BASE COUNT         1382 a          538 c          430 g         1479 t
ORIGIN      
        1 ccttacattg caactgttaa accctacttt atcaaaaata tcgctcactg caaaatttat
       61 atatttttat tatatcataa aattcaaact ataaaattaa aatggaataa tttatcaatt
      121 taagaacacc tacatatttg taaatactta ctatattatc tattctaata attcttcttc
      181 tagctggaac taatataaaa atcatctctg aaagattagg acatactaat ataaaaataa
      241 ctatgaatag atattttctt gttttaaacg atatggataa aaaagcttct gaaaatataa
      301 tcaaagttct ctttaaataa cattccattt tatgtaagta ggcattatat ttttcttaaa
      361 tgtcacttaa atgtcagtta tatataataa tagtaaacaa ctgtatttca ctaatatttg
      421 ctattatcta atagtattta tagtttagat ttgatataat acatgtggta aaattttgat
      481 ttgtaaaaca aaattttacc tacatatatt aaaacaaatt taaaactaag gagacctata
      541 tgttaaaagt attaaaagga aatataattt ttacaaaaac ttcagaaact ttcacagtat
      601 ttgaaaatag ttatattata ctggaaaaag gtaaagtaaa gggaatattt aaagagatac
      661 ctaaggaata caaaaaccta aaagtagtag attacactga taagcttata atacctggta
      721 tgaatgacct ccatgcccat gcctctcaat ttaaaaatct tggaatggct atggataaag
      781 agcttttgcc atggcttgaa acttatacat ttccagaaga atcaaattat aaagatatag
      841 aatatgcaac aaaaatgtat aaaaaatttg taaaagaact ttggaaatct ggaactacaa
      901 gaatagcagt gtttgcaaca gtacataaag aagcctctat gaaacttatg gatatattca
      961 aagaagttgg tcttggagca tacgttggta aagtaaatat gaatatgaat tgccctgata
     1021 ctttattaga aaacactcag gattctatta ctgatacaga agaaattata aataagtata
     1081 gtgatacaga ttctattgta aaaccaataa taacacctag atttatacca agctgtacaa
     1141 gtgaactttt aaaaggttta ggagatttat gtttaaaata taatattcct attcaatcac
     1201 acttatctga aaattatgat gagattgaat gggttagaag tctagaacct gaatctaaat
     1261 tctatggaga tgcatataat agatataatt tatttggtca aactcctact ttaatggctc
     1321 attgtgttca ttgttctcag gatgaaatag atttaatgag agaaaataat gttatggcag
     1381 ttcactgtcc agcttctaac tttaatgttg gtagtggtgc tatgcctatc agaaaattaa
     1441 tcgataataa tattagatta gcacttggat cagatataag cggtggacat acattgtcaa
     1501 tatttaaagc aatggtatct gcaatacaat tatctaaatt atattgggtt aattctggta
     1561 agaagtataa tttcttatct ttatctgagg ctttttatat tgcaaccaaa agtggtggaa
     1621 gtttctttgg aaaagttggt agctttgaag aaggttatga ttttgatgca ttgattattg
     1681 atgattcaaa tttaaatcat gacaattatt ctatacttga aagacttgaa agatttatct
     1741 atgttggtga tgatagaaat atcattcata gatatgtatg tggaaaacta attgaagaac
     1801 ctaatatata attataataa aaattttaat tatatattat ggttaattta tacaactata
     1861 attaataaaa gagtatattt taaatctaaa agctataggt tgaaacatac tctttttatt
     1921 ttgtttattt atagctttag ttattaatca tatataaatc tacaaaacgt attcctagta
     1981 acttatattt tttgatatct acaatcataa gactatatta ttggattcat acctcaaaaa
     2041 tattgccttc tgaacattat tatattcaaa gctatgttaa tttacaatga tatatcctaa
     2101 catgtattga ttaaaaaaaa ttaaaacttg cttttcatct cctatatcta aagaagtggt
     2161 atttagaata aactattgta atattaaagt tgaaattttc tagtttattt actctatagc
     2221 accatatttt aatactatta agtaaaaatg tagttaaaat atatactaat atccctgaaa
     2281 taagtatttc ttttttattt agcacactta ttcgtaaggt attagttatt atatttccaa
     2341 attatagaat aaatattata cttattgcta attataatat taatactgtt aagatatttt
     2401 tcttcatagt tatacccatt atttaataca atttattata aattcaattt ttaaactttt
     2461 cttatctcct tatcagaata aaaatcccct ttacttcctt ttatttttac tatttttaaa
     2521 cttgccatct tctctaatct ccaaagtata aaccaatctt ttacacgcat ttcatcttca
     2581 aacatacagt ttgcaaccac ttcaattaaa ggttgccatt tgtcactgat atttcttaat
     2641 atatatttat caaaataagt ttcttcaaca cttttaattt cgttacctac taatgctcta
     2701 aaaatagaat tttctttaac taacacatcc catttatttt taaattctag tttttcatta
     2761 aagccaattt ctagtgtctt atctaaaaag aatggaaaat cttctggaga catttcactg
     2821 gtaaatgaat atctaattag agcatcttct gtcttttttt catctactaa tgcaatcttt
     2881 atatttttat cttgaaactt actcactaca taatatactc cacacaaatc ttttgggtta
     2941 tttgcacacc atattattat atttctacat tttgataatt tcctatcttc taacaaatct
     3001 ggcttgaata atagtttcgg attattttca aaaacatttc taatcttaaa aatattttct
     3061 cttaattcgt agttatttac atcaaaaata ttacctattg ataaatcatc ttcaaataat
     3121 acaattttat tatgtggtat taactttaac ttcattgctt cttttaataa caaataacaa
     3181 atatcctcaa agcatatatg tgccataaaa ttcacctctt ttaaaattaa caatttattt
     3241 tattataata tataaactgt aattctgaac ctcccatgac taaagtcaca gggttcctgc
     3301 ttcacagaat tttgcatact aaaatatgtc ttactaattc tccacaggct atccccgtag
     3361 ttcctacggt tcttacatac gttatttatt ttgaattgtt attagtctta atccttcttt
     3421 taatatattt atacttgcat ttatatctct atcgtgagtt tcattacaac taggacaaat
     3481 ccattctctt atatttaagt tcttcacttc ctcgttttta tacccacatt tattgcatat
     3541 ttgtgaactt gcaaagaatt tacctacctt tacaatttgt ctaccatgcc aattagcctt
     3601 gtattctaat tgacgaataa attctgacca tgacacatca gaaattgagc gagatagttt
     3661 atgattttta atcatattct ttacttgtaa atcttctatg caaataatat cattctcttt
     3721 tattaattta gtagatagtt tttgtagaaa atcctttctt tgattagcta tatgttcttg
     3781 aagtcttgca acttttaatc ttgctttatt tctatttaaa ctaccgatt
//
LOCUS       DAEPHU010000157         3787 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 01A10CD0081
            SAMN05941466-rid12468953.denovo.160, whole genome shotgun sequence.
ACCESSION   DAEPHU010000157 DAEPHU010000000
VERSION     DAEPHU010000157.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941466
            Sequence Read Archive: SRR6291087
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 3787)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3787)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068158.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 22:43:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,892
            CDSs (total)                      :: 3,805
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 87
            rRNAs                             :: 8, 1, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 55
            CDSs (without protein)            :: 55
            Pseudo Genes (ambiguous residues) :: 0 of 55
            Pseudo Genes (frameshifted)       :: 21 of 55
            Pseudo Genes (incomplete)         :: 28 of 55
            Pseudo Genes (internal stop)      :: 16 of 55
            Pseudo Genes (multiple problems)  :: 8 of 55
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3787
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941466-rid12468953.denovo.160"
                     /strain="01A10CD0081"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            complement(203..583)
                     /locus_tag="KR231_003722"
     CDS             complement(203..583)
                     /locus_tag="KR231_003722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
                     /protein_id="HBH0006045.1"
                     /translation="MCLKKLSKLELVIMKFIWNLDIKTNSYEIIDYMKEEHNLPEKVA
                     LKTLSKLSKKRFLYVQETGKCMYYTVAIKEKAYLEFISRNVQNLLKNNFIRNLLVSFH
                     EEELTEEKIKSLENWVVNWEEAYV"
     gene            complement(784..1977)
                     /locus_tag="KR231_003723"
     CDS             complement(784..1977)
                     /locus_tag="KR231_003723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation:proton antiporter"
                     /protein_id="HBH0006046.1"
                     /translation="MLTSLALIFLLGMASGGIFKRIKLPNLLGMLLTGIILGPYVLNL
                     IDNSILDISSDLRKIALIIILTRAGLSLDINDLKKVGRPAVLMCFIPATFEIIGMIVL
                     APKLLGVSILEAAVMGAVVGAVSPAIIVPKMLKLMEEGYGTEKSIPQMLLAGTSIDDI
                     FVIVMFTVFTGLAQGNSISAISFLQIPVSIILGVIVGAVIGIYLAVFFKKVHMRDSAK
                     GVLLLSISFLMISLETALEGIVPFSGLLAVMSIGIFLQIKYRVVARRLSIKYSKLWVG
                     AEILLFVLVGATVDISYAFKAGIGAVILIFGVLLFRMVGVFFCLIKTNLTIKERLFCM
                     IGYIPKATVQAAIGGVPLAMGMASGQLILTLAVLAILITAPLGAFGIDVTYKKLLTSV
                     KGENK"
     gene            complement(2040..3296)
                     /locus_tag="KR231_003724"
     CDS             complement(2040..3296)
                     /locus_tag="KR231_003724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chloride channel protein"
                     /protein_id="HBH0006047.1"
                     /translation="MIEKFKTLIWIKMIIRIKSVYKTYGGLFFLGLIGIPVGAIIGLI
                     DTIFGTVLLKVTDIRETYPMYLIPFLAVVGVVIAYCYFKFGGKSSKGMNLIFEVGHGE
                     EEIIPLRLVPFIISGTWLTHLFGGSAGREGVAVQIGATFSHWVGKRLPIKNASSIFLV
                     TGMAAGFAGLFETPIAAILFAMEVLVAGSLEYQSLFPAFTASFTASAVSKALGLEKFS
                     FALSSKVVFDLSIFWKLIVLGIIFGMVGGAFAWCLKLSKRKIGNRLKNPMIRIAIIGV
                     CLSVLFLLFYKGRYSGLGTNLIQNSFYGGEIYSFDWLLKFILTILTLSAGFQGGEVTP
                     LFSIGASLGVLLAGFFNLPIELVAALGYASVFGSATNTFFAPVFIGAEVFGYSYLPYF
                     FVVCAISYIFNMDKSIYSLQKISTKQ"
BASE COUNT         1380 a          709 c          403 g         1295 t
ORIGIN      
        1 ttactataga gatgacatat caaaatattt ttaaaaagca atttaagtat tagaagtaat
       61 tgaagttagt aaatataaat gcgtttactt ttaagtattg cttaagggaa taaaaaataa
      121 aaataaactc tgcaaccatc taaaaatagt tgcagagctt acaaaaccaa aattatctaa
      181 attgtaataa aaataataac atttatacat aagcttcttc ccaatttact acccagtttt
      241 ctaacgactt tatcttttcc tctgttagct cctcttcgtg aaatgatact aataaattcc
      301 ttataaaatt attcttcaaa agattttgca catttcttga tataaactct aaatatgcct
      361 tttctttgat tgcaactgta taatacatac acttgcctgt ttcttgaaca tataagaatc
      421 ttttctttga tagttttgat aaagttttta aagctacttt ttctggtaaa ttatgttctt
      481 ctttcatata atcaataatc tcatatgaat tggtttttat atctaaattc caaataaatt
      541 tcataataac taactctaat tttgataatt tttttaaaca catagttatc actccgcttc
      601 tttatctata taattaaata ttacaataat aatttcacaa aatcaattct aataatcata
      661 acatacctta aaatctgttc ttaacttcta ccttcttaat ctcccaaatg atttttttat
      721 attgtattca atagtataat ccttttccaa aatataactt accagttaaa ataatcttta
      781 tttttactta ttctcgcctt ttacagaagt taataatttt ttataagtta catcaattcc
      841 aaaagctcca agaggtgcag ttataagtat agctagaact gctaacgtca aaataagttg
      901 tccagatgcc atccccattg caagtggtac acctcctatt gccgcctgta ctgtagcctt
      961 tggaatatag ccaatcatac agaacaatct ttcctttatt gtcaaatttg tcttaataag
     1021 gcagaagaat actcctacca tacggaataa aagaactcca aatattaaaa ttacagctcc
     1081 aattcctgct ttaaatgcat aacttatatc tactgttgcc cctaccaaaa caaacaagag
     1141 aatttcagca ccaacccata gtttcgaata ctttatagac aatcttcttg caactacacg
     1201 atattttatc tgaaggaaaa tcccaatact cataactgct aataatccag aaaatggcac
     1261 aataccctct aaagcagtct ctaaacttat cattaaaaat gagatactta aaagcaacac
     1321 ccctttagca gaatctctca tatgaacctt cttaaaaaat actgctaaat agattccaat
     1381 cactgctcca actattacac ctaatataat tgatactgga atttgtaaaa agctaatagc
     1441 tgatatacta tttccttgtg ccaatcctgt gaatactgta aacatcacaa ttacgaaaat
     1501 atcgtctata gaagttcctg ctaaaagcat ctgtggaata cttttttctg taccataacc
     1561 ttcttccatt aatttaagca ttttaggtac aataattgcg ggagaaactg ctcctactac
     1621 tgcacccatg actgctgctt ccaatataga aacgcctagt aactttggtg ctaaaactat
     1681 cattccgata atttcaaaag tagctggaat aaagcacata agtacagcgg gtcttcccac
     1741 tttcttcaaa tcgtttatat ctaaagataa tccagccctt gttaatataa taatcaatgc
     1801 aatctttcta aggtcagaag aaatatctag tattgaatta tcaatcaaat ttaaaacata
     1861 tggacctaat ataattcccg taagtaacat tcccaataag ttaggtaatt ttatcctctt
     1921 aaaaatacct cccgaggcca ttcctaataa aaaaatcaaa gctaaacttg tcaacatatt
     1981 cctaccctat cctttctcta atattctttc tcttctaatc atacattatg ttgttttatt
     2041 tattgttttg ttgaaatttt ttgtagtgaa taaatagatt tatccatatt aaatatatat
     2101 gaaatagcgc atactacaaa gaaataaggt aaatagctgt acccaaaaac ttctgcccct
     2161 ataaatacag gtgcaaaaaa agtatttgta gcactaccaa agacactagc atagccaagc
     2221 gctgcaacta attcaattgg caaattaaaa aatcctgcta acaatacacc aagactagct
     2281 ccaatggaaa acaaaggtgt aacctctcct ccttgaaaac ctgctgacaa agtcagtatt
     2341 gtaagtataa actttaacag ccagtcaaat gaataaattt ctccaccata gaaactattt
     2401 tgaattaaat ttgtccctaa acctgaatat cttcctttat aaaataaaag gaataataca
     2461 ctaagacata ctccaataat agcaatcctt atcataggat tttttaatct attccctatt
     2521 tttctttttg acaatttcag acaccatgca aatgctccac caaccattcc aaaaataatt
     2581 cctaaaacaa taagcttcca aaatattgac aagtcaaata caactttaga agaaagtgca
     2641 aaagaaaatt tctctaaccc taaagctttt gatactgcac ttgctgtaaa agaagcagta
     2701 aacgcaggaa aaagcgattg atactccagt gaaccagcaa ccaaaacctc catagcaaat
     2761 agtattgctg ctattggtgt ctcaaataat cctgcaaaac cagctgccat accagttact
     2821 agaaaaatac tagaagcatt ttttataggc aaccttttac ctacccaatg tgaaaaagtt
     2881 gcaccaatct gaacagcaac tccttctcgt cctgcactac caccaaataa atgggttaac
     2941 catgtacctg atattataaa tggaaccaat cttaaaggaa taatttcttc ttctccatgc
     3001 cctacctcaa atattagatt cattccttta ctactttttc ctccaaattt aaaatagcaa
     3061 taagcaataa caactcctac tactgctaaa aatggtatca gatacattgg atatgtttct
     3121 cgaatatctg taacttttag aagaaccgtt ccaaatatgg tatctataag acctataatt
     3181 gcaccaactg gtatacctat gagtcctaaa aaaaatagtc caccatatgt tttataaacg
     3241 cttttaattc ttattatcat tttaatccat attaaagttt taaatttttc tatcatttta
     3301 attcctttct atttgcatca taagattttt tgaaagtttt attacatcaa ctgtagtcaa
     3361 tgtaatgact atcataattg ttttttaaat tgataggata taggtacact cttaacccat
     3421 tcttaataaa ataattaaca tataatctac tattttttct attaattaaa tatttcttca
     3481 aatttaaaaa ataaaaattt agtaagtact tcacctccat tttatcgatt taaacaacaa
     3541 aaaaagctgg tggcatctat gatatcatag aagtcatcag ctcattggca gtttaggata
     3601 ttatcatcca agggagaacc tcattcccat aattattata taatttttta tttttcatat
     3661 gtctatttta tgtaaattgt atttttaatg ttataaataa tataacctat caattaaaat
     3721 attaaagtct ctaatattat gagtgttcaa tacttcatat tatttttatg atatataatt
     3781 taaatga
//
LOCUS       DAEPHU010000158         3767 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 01A10CD0081
            SAMN05941466-rid12468953.denovo.161, whole genome shotgun sequence.
ACCESSION   DAEPHU010000158 DAEPHU010000000
VERSION     DAEPHU010000158.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941466
            Sequence Read Archive: SRR6291087
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 3767)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3767)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068158.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 22:43:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,892
            CDSs (total)                      :: 3,805
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 87
            rRNAs                             :: 8, 1, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 55
            CDSs (without protein)            :: 55
            Pseudo Genes (ambiguous residues) :: 0 of 55
            Pseudo Genes (frameshifted)       :: 21 of 55
            Pseudo Genes (incomplete)         :: 28 of 55
            Pseudo Genes (internal stop)      :: 16 of 55
            Pseudo Genes (multiple problems)  :: 8 of 55
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3767
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941466-rid12468953.denovo.161"
                     /strain="01A10CD0081"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            <1..244
                     /locus_tag="KR231_003725"
     CDS             <1..244
                     /locus_tag="KR231_003725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HBH0006048.1"
                     /translation="RPNVKIEPKRVDSVNATNTKTKTYTVKAGDSLWSICQKQLGNGS
                     LYKKVYELNKSMMDKANKGKNLSKYTIYKGQVLKLG"
     gene            237..2207
                     /locus_tag="KR231_003726"
     CDS             237..2207
                     /locus_tag="KR231_003726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C40 family peptidase"
                     /protein_id="HBH0006049.1"
                     /translation="MVDELVLANDRDVRLVIAHWEDFYEPAVIDGITWEIERRGTPSK
                     LEFTIVMDDILEFCEGNSVRLYYKGIGIFYGYIFQKKRDKENHIKIVAYDQLRYFKNK
                     DTYVYSNKTASELVKMLAKDFNLKYNVIEDTKYKISRIEENKTLFDMILTALDDTLRE
                     KKEMYVLYDDFGRITLKNVASMKLDTVMNNDVIEDFDYNSSIDSDTYTKIKLVRDNEE
                     SGKRDVYIAQDSAHMRSWGILQMFDTVDKNMSEAEIKQKCDILLKLYNKKTKSLSLKN
                     VLGDIRVRAGCLVPVFLSLGDIDLQNYMLVEKVKHTFENNSHFMDLTLVDGDEFASYS
                     SSSYSSGNTNNKNEKQNGPAQSTTSKEDTDMANKINKLLKGKLSNTGNIFVKYSNAYK
                     VNPALMAAISMHESARGTSNIANTKNNFFGMKKNGDYMSFSSVDEGIKRGISNLSRNY
                     IHIGRKTLESIRNKYSSSSDKEWVKCVGAFYKQITGSTYNSNSAGTGVGSNEEAEKNL
                     KDLTYQVQNNNSNTSTNNNNKVSKVIQEAKNQLGKPYKWGGNGPKSFDCSGLMVWAFK
                     RGAGINLKRVSADQSKDSRGKLLCNINDVKAGDLVFFAYNKGKGNVHHVGLYIGNDQY
                     IHAPQTGDVVKISSLSGRQKKKHDFARARRFF"
     gene            2221..2481
                     /locus_tag="KR231_003727"
     CDS             2221..2481
                     /locus_tag="KR231_003727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2577 domain-containing protein"
                     /protein_id="HBH0006050.1"
                     /translation="MSQELLQIIKKAAMDAVETSNPMQIAFGTIESVNPLIVKIEQKA
                     SFEEFFLIQTETFKRYTDKKIGDKLVLIRMQGGQQYLILDRM"
     gene            2486..2905
                     /locus_tag="KR231_003728"
     CDS             2486..2905
                     /locus_tag="KR231_003728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2634 domain-containing protein"
                     /protein_id="HBH0006051.1"
                     /translation="MLPTDNIDYDIEDVSIINFDVRQEPSKTFKLNIEKNRVDGICDD
                     VEALKQTIFLILNTERYEHLIYSRNYGVELNDLIGEPISYVIPELERRITEALIQDDR
                     IENIDNFEFQNIKGKVQCRFSVHTKYGNIKAEKVVSV"
     gene            2918..>3767
                     /locus_tag="KR231_003729"
     CDS             2918..>3767
                     /locus_tag="KR231_003729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015984854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="baseplate J/gp47 family protein"
                     /protein_id="HBH0006052.1"
                     /translation="MTFENIIKRMLDSVPDTFDKREGSIIYNALAPVAIELTETYIAM
                     DELLDQTFVDTASYYYLEKRCKERGITPLEATNTIAKGVFNIDIPIDSRFNLGEYNYV
                     AIERISEGIYKMKCETAGPIFELGQLIPIEYIDKLETAELTEILINGEDEESEDSLRQ
                     RYYDSLNSQSFGGNMQNYKDEVNKIQDVGGVKVYPVWDGGGTVKLVIINSNFKVPSED
                     LVNLVQEEIDPIGHQGQGLGLAPIGHKVTVTGVVSTTINISAEITYKNGYTWENIKSI
                     AEEAIDD"
BASE COUNT         1542 a          410 c          729 g         1086 t
ORIGIN      
        1 tagacctaat gtaaagatag agccaaaacg agttgattca gtcaatgcca caaacactaa
       61 aactaaaaca tatacagtaa aagcagggga tagcctttgg tcaatttgtc agaaacaact
      121 tggtaatggt tcattatata agaaagtata cgaactaaat aaatctatga tggataaggc
      181 aaataagggc aaaaacttaa gtaaatacac tatttataaa gggcaggtgt taaaacttgg
      241 ttgatgaatt agtgttagca aatgatagag atgtaaggtt agtaatagct cattgggaag
      301 atttctacga acctgctgtc attgatggta tcacatggga gatagaaaga agaggaacac
      361 cttctaagtt agaatttaca atagttatgg atgatatatt agagttttgc gaaggaaatt
      421 ctgtaaggct gtattataaa ggaataggta tcttctatgg atatatattt cagaagaaaa
      481 gagataaaga aaatcacatt aaaattgttg cttacgacca gctaagatat tttaagaata
      541 aagatactta tgtatatagt aataaaactg caagtgaact tgtaaaaatg ttggctaaag
      601 attttaattt aaaatacaat gtcatagaag atactaagta taaaatatct aggatagaag
      661 aaaataaaac actctttgac atgatactaa cagcactaga tgatactcta agagagaaaa
      721 aagaaatgta tgttttatat gatgattttg gaagaataac attaaagaat gttgcatcaa
      781 tgaaattaga tactgttatg aataatgatg tcatagagga ctttgactac aattcttcta
      841 ttgatagtga tacttacaca aagattaaac ttgtaagaga caacgaggag tcaggaaaaa
      901 gggatgtata tattgctcaa gactcagctc acatgagaag ttggggaata cttcaaatgt
      961 ttgatacagt agataaaaac atgagtgaag cagaaataaa gcaaaagtgt gatatacttc
     1021 taaaactata taataagaaa actaagtcat taagtttaaa aaatgtgtta ggagatatta
     1081 gagtaagagc aggttgttta gtacctgttt ttttgtcgtt aggagatatt gatttacaaa
     1141 attatatgtt agttgagaaa gtaaaacata catttgaaaa taacagtcat tttatggacc
     1201 taactttggt tgatggagac gaatttgctt cttattcttc atcaagttat agtagtggaa
     1261 atactaataa taaaaatgag aaacaaaatg gtcctgcaca aagtactaca agtaaagaag
     1321 atactgatat ggctaataag attaataaac tacttaaagg taaattatca aatacaggaa
     1381 atatatttgt taaatattca aatgcttata aagttaatcc agcactcatg gctgctatat
     1441 ctatgcacga atcagctaga gggacttcaa atattgcaaa tactaaaaat aatttctttg
     1501 gaatgaaaaa aaatggagat tacatgagtt tttctagtgt agacgaagga ataaaaagag
     1561 gtataagtaa tttatcaaga aactatatcc atataggacg aaaaacttta gaaagcatca
     1621 gaaataaata ttcttctagt tcagacaaag aatgggtaaa atgtgtaggt gcattttata
     1681 agcaaataac aggaagtact tataattcta atagtgcagg cacaggagtt ggaagtaatg
     1741 aagaagcaga aaagaattta aaagatttaa cttatcaagt tcaaaacaat aattctaata
     1801 catcaacaaa caataataat aaagtaagta aagttattca agaagcaaaa aatcaacttg
     1861 gcaagcctta caaatggggt ggtaatggtc caaagagttt tgactgtagt ggtcttatgg
     1921 tgtgggcatt taaaagaggt gcaggaataa atctcaaaag agtttcagca gaccaatcaa
     1981 aagatagtag aggaaaacta ttatgtaaca taaatgatgt aaaagctggt gatttagtat
     2041 tctttgcata caacaaagga aaaggaaatg tacatcatgt tggactatat ataggaaatg
     2101 accaatatat tcatgctcca caaactggtg acgtagtaaa aataagtagt ttaagtggta
     2161 gacaaaagaa aaagcatgat tttgcaagag ctagaagatt cttttaagtg aggtgataaa
     2221 gtgtcacaag aattattgca aataattaag aaggctgcaa tggatgcagt agaaacaagc
     2281 aatccaatgc aaattgcatt tggaactata gaaagtgtta atcctttgat agttaagata
     2341 gaacaaaaag catcttttga agaatttttt ctaatacaaa cagagacttt taaaagatat
     2401 acagataaaa aaatagggga taaattagtc ttaattagga tgcaaggagg acagcaatat
     2461 ttgattttag ataggatgtg atgaaatgtt accaacagat aacattgact atgatataga
     2521 agatgtatcg ataattaatt ttgatgttag acaagaacca agtaagacgt ttaaattgaa
     2581 tatagagaaa aatagagtag atggtatttg tgatgatgta gaagcattaa aacaaaccat
     2641 ttttttaatt ttaaatactg aaaggtatga gcaccttatt tattctagaa attatggtgt
     2701 tgaattaaat gatttaattg gagaacctat ttcatatgta atacccgaac ttgaaagaag
     2761 gataacagaa gcactaattc aagatgatag gattgaaaat atagataatt ttgagtttca
     2821 aaatataaag ggtaaagtac aatgtagatt ttcagttcat acaaaatatg gaaatataaa
     2881 agcagagaag gtggtgagtg tataattgtt tgagttaatg acatttgaaa atataattaa
     2941 aagaatgtta gatagtgtac cagatacttt tgataaaagg gaaggttcta taatatataa
     3001 tgctcttgct cctgttgcta tagaacttac agaaacatac attgctatgg atgaattact
     3061 agaccaaaca ttcgtagata ctgctagtta ttattattta gagaagagat gtaaagagag
     3121 aggtattaca ccacttgaag ccactaatac aattgcaaaa ggagttttta acatagatat
     3181 tcctattgat tctaggttta atctaggaga atataactat gtagcaattg agagaatatc
     3241 tgaaggtata tataagatga aatgtgagac tgcgggacct atttttgagt tgggacaact
     3301 aatacctatc gaatatatag acaaattaga aacagcagaa ctgacagaaa tactgataaa
     3361 tggagaagat gaagagagtg aggatagttt aagacaaaga tattatgata gcctaaattc
     3421 acagagcttt ggtggaaata tgcaaaatta taaagatgaa gttaacaaaa tacaagatgt
     3481 tggaggagtt aaggtttatc ctgtgtggga cggtggagga actgttaagt tagtaataat
     3541 taactctaat ttcaaagtac catcagagga tttagttaat ttagtgcaag aagaaattga
     3601 cccaattgga catcaaggac aaggcttagg attagcacca atagggcata aagttactgt
     3661 tacaggtgtt gtaagtacaa ctataaatat atcagcagag ataacataca aaaatggcta
     3721 cacttgggag aatataaaat caattgcaga agaagcaata gacgact
//
LOCUS       DAEPHU010000159         3686 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 01A10CD0081
            SAMN05941466-rid12468953.denovo.162, whole genome shotgun sequence.
ACCESSION   DAEPHU010000159 DAEPHU010000000
VERSION     DAEPHU010000159.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941466
            Sequence Read Archive: SRR6291087
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 3686)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3686)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068158.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 22:43:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,892
            CDSs (total)                      :: 3,805
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 87
            rRNAs                             :: 8, 1, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 55
            CDSs (without protein)            :: 55
            Pseudo Genes (ambiguous residues) :: 0 of 55
            Pseudo Genes (frameshifted)       :: 21 of 55
            Pseudo Genes (incomplete)         :: 28 of 55
            Pseudo Genes (internal stop)      :: 16 of 55
            Pseudo Genes (multiple problems)  :: 8 of 55
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3686
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941466-rid12468953.denovo.162"
                     /strain="01A10CD0081"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            261..620
                     /locus_tag="KR231_003730"
     CDS             261..620
                     /locus_tag="KR231_003730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002583503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBH0006053.1"
                     /translation="MKLRESYTCPLELVHDIIKGKWKTIIIFQLRNGKCSFSELHHSI
                     AGITQKMLLEQLRELKHFGLIDKKTYDGYPLKVEYFLTGQGEKMLSAIKIMQEIGIDY
                     MVEHGMTEILDEKGICY"
     gene            710..1261
                     /locus_tag="KR231_003731"
     CDS             710..1261
                     /locus_tag="KR231_003731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HBH0006054.1"
                     /translation="MKKALLIIDVQNDYFPNGKCQLYKPEIALNTIKDLLKIFRKQNL
                     PIIYIRHESIHGTFFNPNTNGVQIHNDIKPLDTETVIVKHYPNSFYETNLQNKLVEIE
                     VTKLVVCGMMTHMCIDTTIRAAKDYGYEITLISNGCATKELKWNGVNIPADTVQSIFM
                     ASLNQKFANVITSTEFLSNEITR"
     gene            1245..1610
                     /locus_tag="KR231_003732"
     CDS             1245..1610
                     /locus_tag="KR231_003732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009291267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBH0006055.1"
                     /translation="MKLRDEYTCPLELIHDMIKGKWKPIILWRLRLGATSLSKLENDI
                     DGITQKMLLEHLKELIDYGFVDKKTFSGYPLHVEYFLTEDMGNQILEALRIMQHIGIE
                     YLRKNGMENELTEKHVIPD"
     gene            1698..2198
                     /locus_tag="KR231_003733"
     CDS             1698..2198
                     /locus_tag="KR231_003733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015393784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbhB/YbcL family Raf kinase inhibitor-like
                     protein"
                     /protein_id="HBH0006056.1"
                     /translation="MYISSIGISNGIIEKKYGSHGVQFNENDVPTYSIPFKIENAPDK
                     TVSFAFILEDKDAYPVTGFIWVHWLGANLTRSELKENESQTAKDFIQGANSWTSILGN
                     QQTREQTSCYGGMAPPDKAHIYELHVFALDKLLDLKNGFYLNELYQEMEGHILEEAVL
                     KGLYEK"
     gene            2188..2703
                     /locus_tag="KR231_003734"
     CDS             2188..2703
                     /locus_tag="KR231_003734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016285890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HBH0006057.1"
                     /translation="MKSKPVKVGLRTIKTVLSAFLCFLIDSLRASSVPFYAVIASILC
                     IQPDMENSLSVAKNRELSTIIGGILGMLFLLMERIFLPIQPEILRELTLSILLIPIIN
                     LSVLLKQKKGTFLTCVVFLCVTVTHEKDISPIWFAWNRIVDTSLGIGISLAVNSFPFH
                     KFKVGGTMGKY"
     gene            2697..2978
                     /locus_tag="KR231_003735"
     CDS             2697..2978
                     /locus_tag="KR231_003735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HBH0006058.1"
                     /translation="MLIVEFTEKEDAVFQQAVEWLSSKLAYTPASFNQQKKGFDIDPL
                     TRTFTNEEGTSIYLTAKEFDLLYFLSSHKGQVFTKEQIYEKVWGYDNFY"
     gene            3132..3322
                     /locus_tag="KR231_003736"
                     /pseudo
     CDS             3132..3322
                     /locus_tag="KR231_003736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003064779.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4177 domain-containing protein"
     gene            3346..3570
                     /locus_tag="KR231_003737"
     CDS             3346..3570
                     /locus_tag="KR231_003737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008393106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0006059.1"
                     /translation="MIGIKKRDIKKALKAGAKAGGSSYADVLADIEATIDEVMNSTDP
                     EVQANFKKYFGNKRPTPEEYIYKITKKTRV"
     gene            3592..>3686
                     /locus_tag="KR231_003738"
     CDS             3592..>3686
                     /locus_tag="KR231_003738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006863419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HBH0006060.1"
                     /translation="MKNEMWVLCPICNNKTRTKVREDTELINFPL"
BASE COUNT         1329 a          501 c          721 g         1135 t
ORIGIN      
        1 ttccccatag aataccttat cgcctaaatc attacgagaa agcccagctt tttcacgggc
       61 ttctctgatt gccagcccta gcggtctgaa atcaaaagta tgtgtttctt ttgtttttct
      121 cattttaaat caccatacat gagtttatac ttcatggttc gtatttagaa tgtgttaaaa
      181 gtgcatatat tagggtaata aaatatgttt tgaaatattg agcttaaaca tgtaagatat
      241 ttcacatagg agatgataaa atgaaactta gagaaagcta tacatgtcca ttagaacttg
      301 ttcatgatat tataaaggga aaatggaaaa cgataattat ttttcaactt agaaatggaa
      361 aatgctcttt ttccgaactc catcacagta tagcaggaat tactcaaaaa atgctattgg
      421 aacaactgcg tgaattaaaa cactttggct taattgataa aaaaacatat gatggatatc
      481 ctctaaaagt agaatacttt ttaactggac agggagaaaa gatgctatca gcaattaaga
      541 taatgcaaga aattggtata gattacatgg tagagcatgg tatgacagaa atccttgatg
      601 aaaaaggaat ttgttattaa actctatcat atacacgaaa aagtaagtaa tttacttaga
      661 aactattatc ttatattatt taattagaat taagagagga tatgagagta tgaaaaaagc
      721 attacttatt attgatgtgc agaatgatta ttttcctaat ggaaagtgcc agttgtataa
      781 accagagatt gcgttgaata caataaaaga tttattgaaa atttttagaa agcaaaactt
      841 gccaattatt tacattcgcc atgagtctat ccatggaaca ttttttaatc caaatacaaa
      901 tggtgtacaa atccataatg atattaaacc attagataca gaaacagtta ttgttaaaca
      961 ttatccaaat agtttttatg aaacgaattt gcaaaacaaa ctggtagaga ttgaggtaac
     1021 gaaattggtt gtttgtggaa tgatgacaca tatgtgtatt gacacaacta taagagctgc
     1081 caaagattat ggctatgaga ttacactaat atcaaatggt tgtgcgacca aggaattaaa
     1141 atggaatgga gtcaatatcc cagcagatac agttcaaagc atatttatgg cttctttaaa
     1201 tcagaaattt gctaatgtta ttacaagcac ggagtttttg tcaaatgaaa ttacgagatg
     1261 aatatacatg tcctttggaa ttaattcatg atatgataaa gggaaaatgg aagccaatta
     1321 ttttatggcg cttacgatta ggtgctactt cattatctaa attagagaat gatattgatg
     1381 gaattacaca aaaaatgctt ttggaacatt taaaggaact tatagattat ggatttgttg
     1441 ataaaaaaac attttctggt tatccacttc atgtcgagta ttttttgacg gaagatatgg
     1501 gaaatcaaat actagaagca ttacgaatta tgcaacatat agggattgaa tatttaagga
     1561 aaaatggaat ggaaaatgaa ttaactgaga aacacgtgat tccagactaa tacctacaaa
     1621 aaagtgggta atttacgttt tgcttcctct ttgttaatat atatctgtaa ttaaacgata
     1681 tacaaggagg aaaatttatg tatatttcaa gtataggaat ttctaatgga attattgaaa
     1741 aaaaatatgg tagtcatgga gtgcaattca atgaaaatga tgtgccaacg tattcaattc
     1801 cgttcaaaat tgaaaatgca ccagataaaa cggtttcctt tgcctttata ctggaagata
     1861 aagacgcata tccagtgacg ggttttatat gggtgcattg gttaggagct aatctaacaa
     1921 gaagtgaatt aaaggaaaac gaaagccaga cagcaaagga ctttatacaa ggtgcgaata
     1981 gctggacaag catattgggg aatcagcaaa ccagagaaca gacaagctgt tatggtggaa
     2041 tggcaccacc agataaagca catatttatg agcttcatgt atttgccctt gataaactgc
     2101 ttgatttaaa aaacggattt tatcttaatg aactctatca agaaatggag gggcacatcc
     2161 ttgaagaagc tgtactaaaa gggttgtatg aaaagtaagc ctgttaaagt tggattgcgg
     2221 acaattaaga cggtactttc tgcgttcctt tgttttttga tagatagctt aagagcttca
     2281 agtgttcctt tttatgcagt gattgcgtct atactgtgca tacagccaga tatggaaaac
     2341 agtttgagcg ttgctaaaaa cagggaactt tcaacaatta tcggcggtat actgggaatg
     2401 ctctttttgc ttatggaaag aatttttttg cccattcagc cagaaatact tcgggaattg
     2461 actttatcta ttttattgat tccaatcatc aatctgtctg tactgttgaa acagaaaaaa
     2521 ggaacatttt taacgtgcgt tgtattctta tgcgtaacag taacacatga gaaagatata
     2581 agtcctattt ggttcgcatg gaataggatt gttgacactt cattagggat tggtatttca
     2641 ctggcagtaa actctttccc ctttcataaa tttaaggtag gtggtactat gggaaaatac
     2701 tgattgttga atttactgaa aaagaggacg ctgttttcca acaagcggtg gaatggctgt
     2761 cctctaaact tgcttacacc cctgcttctt ttaatcagca gaaaaaagga tttgatatag
     2821 acccattaac ccgtaccttt accaacgaag agggaacgtc tatatatctg actgctaaag
     2881 aatttgacct actatatttc ctttccagcc acaaaggaca ggtgttcaca aaagaacaga
     2941 tttatgaaaa ggtatgggga tatgacaatt tttattagtc tggcaataat gaagaaaaaa
     3001 gaattttaga aaagtgaggt gtgcttatgg atttatctat tttggtagta gtattgatat
     3061 tgggtgtggg tattccttta agaaataagg caatcaaaaa atacagataa aatatgaaaa
     3121 agaaaggaaa aatgaaaaaa tatgaatatt tagaaattga ttatactgcg aaaggtgttg
     3181 tattcctttg caccgataaa cataaggaag ttataaatag ctatgcagaa aatgggtatc
     3241 gctatgcggg ttcgtgccta cagaaattga cgcaaaaggc tgtatgcgaa agatagattt
     3301 aatttttgaa aaagaagatt aacgtatttt agggagttgg ttcttgtgat aggaattaaa
     3361 aaacgagata ttaaaaaagc attgaaagct ggtgcaaagg ctggtggttc ttcgtatgct
     3421 gatgttttgg ctgatattga agcaacgatt gatgaagtta tgaacagcac cgacccagaa
     3481 gtgcaggcaa atttcaaaaa gtattttgga aataaacgcc ctacaccaga ggaatatatc
     3541 tataaaatca cgaagaaaac acgagtttaa agaattagta agggtggttc tgtgaaaaat
     3601 gaaatgtggg tattatgtcc tatttgcaat aataagacac gaactaaagt gcgagaagat
     3661 acggaattga taaattttcc tttgtt
//
LOCUS       DAEPHU010000160         3681 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 01A10CD0081
            SAMN05941466-rid12468953.denovo.163, whole genome shotgun sequence.
ACCESSION   DAEPHU010000160 DAEPHU010000000
VERSION     DAEPHU010000160.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941466
            Sequence Read Archive: SRR6291087
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 3681)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3681)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068158.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 22:43:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,892
            CDSs (total)                      :: 3,805
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 87
            rRNAs                             :: 8, 1, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 55
            CDSs (without protein)            :: 55
            Pseudo Genes (ambiguous residues) :: 0 of 55
            Pseudo Genes (frameshifted)       :: 21 of 55
            Pseudo Genes (incomplete)         :: 28 of 55
            Pseudo Genes (internal stop)      :: 16 of 55
            Pseudo Genes (multiple problems)  :: 8 of 55
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3681
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941466-rid12468953.denovo.163"
                     /strain="01A10CD0081"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     repeat_region   169..592
                     /inference="COORDINATES: alignment:crt:1.2"
                     /inference="COORDINATES: alignment:pilercr:v1.02"
                     /rpt_family="CRISPR"
                     /rpt_type=direct
                     /rpt_unit_range=169..197
                     /rpt_unit_seq="gttttagattaactatatggaatgtaaat"
     gene            756..929
                     /locus_tag="KR231_003739"
     CDS             756..929
                     /locus_tag="KR231_003739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433557.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CopG family transcriptional regulator"
                     /protein_id="HBH0006061.1"
                     /translation="MSSKMGRPKVDNPKNIDVKVRFDENTHKKLLDYCEKENLTRTEA
                     IRKGVDLLLEEDK"
     gene            1053..1880
                     /locus_tag="KR231_003740"
     CDS             1053..1880
                     /locus_tag="KR231_003740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toxin Bro"
                     /protein_id="HBH0006062.1"
                     /translation="MNNELMNFENNELGIKIRTIKYEDGSIGINAEDTAVGFGWCQTQ
                     NKNGKQYVSIRWETINKYCKEFGFLNLLGKDEYIPESLFYLLGMKAKNEIAVKFQTWL
                     AVDVLPSIRQTGAYITNNANPEKLREKASEIEKLQLAYNSTSMLKELLDGAGFDNKSK
                     LLTAKTLYKKAGIDLPIEIEEEESFFDTKQIASKLKIYSKSNKPAQLAVCEIIKKIDL
                     EENEVKGVWETNGSWTGTVNKYTKSVIDKVRNWIEENNRPAKIAGEKKNYHVVYKIE"
     gene            1943..2119
                     /locus_tag="KR231_003741"
     CDS             1943..2119
                     /locus_tag="KR231_003741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0006063.1"
                     /translation="MCENLLNEYNLKTDEDVEYFVKFATLLYKLKQDNEEKFQEYAEI
                     LRGILREQQERENK"
     gene            complement(2532..2735)
                     /locus_tag="KR231_003742"
     CDS             complement(2532..2735)
                     /locus_tag="KR231_003742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008982964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBH0006064.1"
                     /translation="MYFNIDKLLESKGRTRYWLAKEVGIAYPNMMKLANNETSSIKLD
                     LFEKLCLVLECTPNELVTLSSKE"
     gene            2979..3365
                     /locus_tag="KR231_003743"
                     /pseudo
     CDS             2979..3365
                     /locus_tag="KR231_003743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013726857.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ORF6N domain-containing protein"
BASE COUNT         1457 a          371 c          647 g         1206 t
ORIGIN      
        1 tagagatttt gcagtgagca atatttgcga taaattgaag tttaacaatt ggaatacaag
       61 gtattgaggg tgtgtgataa atgttatcaa ttgcactact catggttcac tgcaaatttg
      121 agagagatgc gtatgtgtag gtattggaaa tgccaagttt attttggggt tttagattaa
      181 ctatatggaa tgtaaattaa cctttttatt gttgttgtta ttcttattgt tattcgtttt
      241 agattaacta tatggaatgt aaatgttgta agaagtatca ttctattttt taatctttct
      301 gttttagatt aactatatgg aatgtaaata gtacatataa tgagtcttta acatcagtta
      361 tgaaaggttt tagattaact atatggaatg taaatgattg tactttagcg tctgcactag
      421 ctttgtctat cgttttagat taactatatg gaatgtaaat tattttacag atgaacaatt
      481 acagttactt cttgaatgtt ttatattaac taagtggtat gtaaataatg gaagcaagat
      541 aatttttaaa ggtatggata attgttttat attaactatg tggattcaaa attaaataga
      601 aaaaagaaag cacttactta aatagtaggt gcttttgttt tgctcaaaat tggtcggttg
      661 agtaaaataa ttagaaaaaa ttgggataag ttattgactt tttggaacac aaataatata
      721 attatattat ggaacacaaa aagtgaggtg aaacaatgag ttctaaaatg ggaagaccaa
      781 aagttgataa tcctaaaaat attgatgtca aagtaagatt tgatgaaaat actcataaaa
      841 aattattaga ttattgtgag aaagaaaatc ttactagaac agaagcaata agaaaaggag
      901 tagacttact tttggaggaa gataagtaaa aaagtagccc aacgccgacc aaagcatact
      961 ggactactta acctagagtt atctctatat gaaatattct atcatgtaaa gataactctt
     1021 tcaagataat aaatcgaaag ggtgattttt gtatgaataa tgaactgatg aattttgaaa
     1081 ataatgaatt aggaataaaa ataagaacta ttaaatatga agatggaagt ataggaatta
     1141 atgcagagga tacagctgta gggtttggat ggtgtcagac acagaataaa aatggtaagc
     1201 aatatgtatc aattagatgg gaaactatta ataaatactg taaagaattt ggtttcctca
     1261 acttgttggg gaaagatgag tatatacctg aatcattatt ttatctttta ggtatgaaag
     1321 ctaaaaatga aatagcagta aaatttcaaa catggttagc agtagatgta ctaccatcaa
     1381 taagacaaac tggtgcatac ataactaaca atgctaatcc cgaaaaacta agagaaaaag
     1441 caagtgagat tgaaaagtta caattagcct ataacagcac atctatgtta aaagaattgc
     1501 tagatggtgc aggatttgac aataaatcca aactattaac agctaaaaca ttatataaaa
     1561 aggcaggcat tgatttacct atagaaattg aagaagagga atctttcttt gacacaaaac
     1621 aaatagcatc taaactgaaa atatattcta agagtaataa accagcacag ttggctgttt
     1681 gtgaaattat taaaaagatt gatttagaag aaaacgaagt caaaggcgtt tgggaaacta
     1741 atggttcttg gactggtact gtaaataaat atacaaagag tgtaatagat aaggttagaa
     1801 attggataga ggaaaataat agacctgcta agattgcagg tgaaaagaag aattatcatg
     1861 tggtttataa gattgagtaa atttatcagt tgtattaaat aatttagttt agtttatttt
     1921 agttttgagg gggattaata caatgtgtga gaatttactt aatgaatata atttaaaaac
     1981 tgatgaagat gtagaatact ttgtaaagtt tgctacatta ttatataaat taaaacagga
     2041 caatgaagaa aaatttcaag agtatgcaga gatattgaga ggtattctta gggaacaaca
     2101 agagagagaa aataagtaaa ataatataga taaagcactt gaatattaca tagtttcaag
     2161 tgctttgttt ggtataaaat ggtataatag agataagagt tatattaact atgtggtatg
     2221 taaagaatgt ataaggcatc ttctcaaatt ctgcgttggt cattttatat taactatgtg
     2281 gtatgtaaag tgcgttaact gcaataatgc tgaactcatt tcttgatttt atattaacta
     2341 agtggtatgt aaatgttaat tccttcaacc ttctaataga agatgctttt aggtttatat
     2401 taactaagtg gtatgtaaat gtttcaacat ttgacatgtg ctgtggagta atgtttatgt
     2461 tttatattaa ctatgtggat tcaaaattaa atagaaaaaa gaagcactta cttaaatagt
     2521 aggtgctttt gttattcttt gctagataaa gtaacaagtt cattaggtgt acattcaaga
     2581 acaagacaaa gcttttcgaa taaatctaat tttatagaac ttgtttcatt gttagctaat
     2641 ttcatcatgt taggataagc tatacctact tctttagcta accaatatct agttcgacct
     2701 ttggattcaa gtaatttatc aatgttaaaa tacatttttt cacctcttaa gtatattata
     2761 caacaattat ataatgtttg caatatataa tatgcaaaca atataattat ataatgttga
     2821 cattatataa tgtgtgcgat ataatatact taaggaataa aaaataagag ccactcgccc
     2881 ctaccaagtt tgagtaactc ttattgacat atactacata tacattaatt atagtatatg
     2941 tcattcctta aaaaaaatca attaaggagt gtgtttttat gaacaattta gtactaatta
     3001 acaatcaaga agtgcaagtt aaggaattta ataatcaaag agtagttaca tttaaagaaa
     3061 ttgacagagt acatgaaaga gtagaaggaa cagcaggtag aaattttaga gaaaataaga
     3121 agcactttat aaaaaatgag gactattttt atttagaagg aaaagaatta tcaacaatta
     3181 aacagacaac gaatttcgtt ggcagtaatg caagagaatt aatcttatta actgaaacag
     3241 gttatctaat gttagtaaaa tcttttacag atgatttagc ttggaaagta caaagacaat
     3301 tggtaaatag ttattttaga gttaaagaag aaaagaaaga aatgaaagca ttagaaaaat
     3361 tagaaacagt taatgagtca attaggttaa taactccaat ttttgatgat ttaaacattg
     3421 ataaaagtat gaaacttctt gtaactaaga ctttttttga aagagcaggt attgaattgc
     3481 ctcttgaagt tgaagaaaaa gaacattttt atgatacaaa gcagattgca aaaaaattag
     3541 gactttacac aatgtctaat aaaccagcat ttatggcagt taagcaaatt ataagaaagc
     3601 ttgatattaa agaagatgaa atgaaaacag tattagaaac gaatggcaat tggactggta
     3661 ctgtaacaaa atattctaat a
//
LOCUS       DAEPHU010000161         3499 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 01A10CD0081
            SAMN05941466-rid12468953.denovo.164, whole genome shotgun sequence.
ACCESSION   DAEPHU010000161 DAEPHU010000000
VERSION     DAEPHU010000161.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941466
            Sequence Read Archive: SRR6291087
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 3499)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3499)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068158.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 22:43:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,892
            CDSs (total)                      :: 3,805
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 87
            rRNAs                             :: 8, 1, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 55
            CDSs (without protein)            :: 55
            Pseudo Genes (ambiguous residues) :: 0 of 55
            Pseudo Genes (frameshifted)       :: 21 of 55
            Pseudo Genes (incomplete)         :: 28 of 55
            Pseudo Genes (internal stop)      :: 16 of 55
            Pseudo Genes (multiple problems)  :: 8 of 55
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3499
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941466-rid12468953.denovo.164"
                     /strain="01A10CD0081"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            <1..238
                     /locus_tag="KR231_003744"
     CDS             <1..238
                     /locus_tag="KR231_003744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HBH0006065.1"
                     /translation="RPNVKIEPKRVDSVNATNTKTYTVKAGDSLWSICQKQLGNGSLY
                     KKVYELNKTMMDKANKGKKVPKYTIYKGQVLRLV"
     gene            231..2123
                     /locus_tag="KR231_003745"
     CDS             231..2123
                     /locus_tag="KR231_003745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C40 family peptidase"
                     /protein_id="HBH0006066.1"
                     /translation="MSDDLVLANDRDIRLVIAHWEDFYEPAVIDGITWEIERRGSPSK
                     LEFTIAMDDILEFCEGNSVRIYYKGIGIFYGYIFQKKRDKENHIKIVAYDQLRYFKNK
                     DTYVYSNKTASELVKMLAKDFNLKYNVIEDTKYKISRVEENKTLFDMVLTALDDTLRE
                     KKEMYVLYDDFGRITLKNVASMKLDTVMNNDVIEDFDYNSSIDSDTYTKIKLVRDNEE
                     TGKRDVYIAQDSTHMRSWGILQMFDTVDKNMSEAEIKQKCDILLKLYNKKTKSLSLKN
                     VLGDIRVRAGCLVPVFLNLGDIKLQNYMLVEKVKHTFENNSHFMDLTLVDGDEFASYS
                     SSSYSSGNTNNKDEKKNGPAQSITKKNTGKKVPAIFTAYYPGNNAMEGGKTDCNGKPL
                     DVKSRTVAGPMNREGVKKTWYTDDFLKKHPVFEYGDKVKIILPGTAYDNKVYTVKDNG
                     GRIYVETNGTYHIDVLLANASECKKFGRKNGYIIIGGDEEQTYQVEGNNQSSTNNNSK
                     EDKLISIAKSKLGCNYVYGAEGPNNFDCSGFTQWCYKQIGIKIPRTASAQSKAGKAVD
                     LKDRSKWKAGDLLCRIGGGSSNHVVMYIGNNQIIHSPQTGDVVKIESVNSYRKGKAYT
                     HVRRFI"
     gene            2137..2397
                     /locus_tag="KR231_003746"
     CDS             2137..2397
                     /locus_tag="KR231_003746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2577 domain-containing protein"
                     /protein_id="HBH0006067.1"
                     /translation="MSQDLLQIIKKAAMDAVETSNPMRVVFGTIESISPLRVKIEQKL
                     SIGEIFLIQTDTFKRYTDKKIGDKLVLIRMQGGQQYLILDRM"
     gene            2402..2821
                     /locus_tag="KR231_003747"
     CDS             2402..2821
                     /locus_tag="KR231_003747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2634 domain-containing protein"
                     /protein_id="HBH0006068.1"
                     /translation="MLPSDNLDYDIEDVSIINFDVRQEPSKTFKLHIEKSKIDGICDD
                     VEALKQTIFLILNTERYQHLIYSWNYGVELNDLIGEPISFVIPELERRIKEALIQDDR
                     VENVDNFEFENIKGKVQCKFSVHTKYGNIKAEKVVSV"
     gene            2834..>3499
                     /locus_tag="KR231_003748"
     CDS             2834..>3499
                     /locus_tag="KR231_003748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015984854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="baseplate J/gp47 family protein"
                     /protein_id="HBH0006069.1"
                     /translation="MTFENIIKRMLDSVPNTLDKREGSIIYNALAPVAVELTETYIAM
                     DELLDQTFVDTASYYYLEKRCKERGITPLPATNTIAKGVFNIDIPLDSRFNLGEYNYI
                     AIERISEKTYKMKCETAGPIFELGKLIPIEYIDGLETAELTEILINGEDEESEDSLRQ
                     RYYDSLNSQSFGGNIQNYKDEVNKIQDVGGVKVYPVWDGGGTVKLVIINSNFKVPSED
                     LVNL"
BASE COUNT         1415 a          381 c          696 g         1007 t
ORIGIN      
        1 tagacctaat gtaaagatag agccaaaacg agttgattca gtcaatgcca caaacactaa
       61 aacatataca gtaaaagcag gggatagcct ttggtcaatt tgtcagaagc aacttggtaa
      121 tggttcgtta tacaagaaag tatatgagtt aaataaaaca atgatggata aagctaacaa
      181 gggtaaaaaa gtacctaaat ataccatcta taaagggcag gtgttgaggc ttgtctgatg
      241 atttagttct ggcgaatgat agagatataa ggctagttat tgcacattgg gaagatttct
      301 acgaacctgc tgtcattgat ggtatcacat gggagataga aagaagaggt tcaccttcaa
      361 agttagagtt tactatagca atggatgata tattagagtt ttgcgaaggt aattctgtaa
      421 ggatatatta taagggaatt ggcatatttt atggatatat atttcagaag aaaagagata
      481 aagaaaatca cattaaaata gttgcttatg accagttgag atattttaaa aataaagata
      541 cttatgtata tagtaataaa acagcaagtg aacttgtaaa gatgttggct aaagatttta
      601 atttaaaata caatgtcata gaagatacaa aatataaaat atcgagagtt gaagaaaata
      661 aaacactctt tgatatggtc ttaactgcac tagatgatac tctaagagag aaaaaagaaa
      721 tgtatgtgtt atatgatgat tttggaagaa taacattaaa gaatgttgca tcaatgaaat
      781 tagatactgt tatgaacaat gatgtaatag aagactttga ctataattca tcaatagata
      841 gtgatactta cacaaagatt aaacttgtga gagataatga agaaacagga aaaagagatg
      901 tgtatattgc tcaagactca acgcatatga ggagttgggg aatacttcaa atgtttgata
      961 cagtagacaa aaacatgagt gaagcagaga taaaacaaaa gtgtgatata cttctaaaac
     1021 tatataataa gaaaactaag tcattaagtt taaaaaatgt acttggagat attagagtga
     1081 gagcaggttg tttagtacct gtttttttaa atctaggaga tattaaactt caaaattata
     1141 tgctagttga gaaagtaaaa catacttttg aaaataacag tcattttatg gatttgactc
     1201 ttgttgatgg agatgaattt gcttcttatt cttcaagctc atattcaagt ggaaatacta
     1261 acaataagga tgaaaagaaa aatggtcctg cacaaagtat tacgaaaaaa aatacaggta
     1321 aaaaagttcc tgctatattt actgcatatt atccagggaa caatgcaatg gaaggcggaa
     1381 aaacagattg caatggaaag ccacttgatg taaaatcaag aactgttgct ggtccaatga
     1441 atcgagaagg agttaagaaa acttggtata ctgatgattt tctaaagaaa catccagttt
     1501 ttgaatatgg agataaagta aaaattatac ttcctggtac tgcctatgac aacaaagtat
     1561 atacagttaa agataatgga ggaagaatat atgttgaaac aaacggaaca tatcatatag
     1621 atgtactatt agctaatgct agtgaatgta aaaaatttgg tagaaagaat ggctatataa
     1681 ttataggtgg agatgaagaa caaacatatc aagttgaagg taataaccaa agtagtacaa
     1741 ataataactc taaagaagat aaattaatta gtatagcaaa aagtaaactg ggttgtaatt
     1801 atgtgtatgg agcagaaggt cctaataatt ttgattgcag tgggtttact caatggtgtt
     1861 ataaacaaat aggtataaaa attcctcgta ctgcttctgc acaaagtaaa gcaggaaaag
     1921 cagtagattt aaaagataga agcaagtgga aagcaggaga cttattatgt agaattggag
     1981 gaggaagtag taatcatgtt gtaatgtata ttggaaacaa tcaaataatt cattcaccac
     2041 aaacaggaga tgtggtaaaa atagagtctg ttaattctta tagaaaagga aaagcataca
     2101 cacatgtgag aagatttata taagtgaggt ggcaatatga gccaagattt attacagata
     2161 ataaaaaaag ctgcaatgga tgcagtagaa acaagcaacc caatgagggt tgtatttgga
     2221 acaatagaaa gtattagtcc tctaagagtt aagatagaac aaaaactatc tattggtgaa
     2281 atttttctaa tacaaacaga tacatttaaa agatatacag ataaaaaaat aggagataaa
     2341 ttagtcttaa ttcgtatgca aggagggcaa caatacttga ttttagatag gatgtgataa
     2401 agtgttacca agtgataatt tagattatga tattgaagat gtatcaataa ttaattttga
     2461 tgtaagacaa gagccaagta agacatttaa acttcatata gaaaagtcta agattgatgg
     2521 tatttgtgat gatgtagaag cattaaaaca gaccatcttt ttgattttaa acacagagag
     2581 ataccaacat ctaatatata gttggaatta tggagtcgag ttgaacgacc ttattggaga
     2641 gcctatatcc tttgtaatac cagagttaga gagaagaatc aaagaagcac taattcaaga
     2701 tgatagggtt gaaaatgtag ataattttga gtttgaaaat ataaagggta aagtacaatg
     2761 taaattttca gttcatacaa aatatggaaa tataaaagca gagaaggtgg tgagtgtata
     2821 attgtttgag ttaatgacat ttgaaaatat aattaaaaga atgttagata gtgtacctaa
     2881 cacacttgat aagagagaag gttctataat atacaatgcc ttggcaccag ttgcagtgga
     2941 gcttacagaa acatatattg ctatggatga attactagac caaacattcg tagatactgc
     3001 tagttattac tatttagaga agagatgtaa agagcgagga attacacctt taccagccac
     3061 taatacaatt gctaaaggag tttttaacat agatattcca cttgattcta ggtttaatct
     3121 aggagaatac aattatattg caattgagag aatatctgaa aaaacatata aaatgaaatg
     3181 tgaaactgct ggacctatat ttgagttagg aaaactaata cctattgaat atatagatgg
     3241 tcttgaaact gctgaactaa ctgaaatctt gataaatgga gaggatgaag agtcagaaga
     3301 tagtttaaga caaagatatt atgatagcct aaattcacag agctttggtg ggaatataca
     3361 aaactataaa gatgaagtta acaaaataca agatgttgga ggagttaagg tttatcctgt
     3421 gtgggacggt ggaggaactg ttaagttagt aataattaac tctaatttca aagtaccatc
     3481 agaggattta gttaattta
//
LOCUS       DAEPHU010000162         3442 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 01A10CD0081
            SAMN05941466-rid12468953.denovo.165, whole genome shotgun sequence.
ACCESSION   DAEPHU010000162 DAEPHU010000000
VERSION     DAEPHU010000162.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941466
            Sequence Read Archive: SRR6291087
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 3442)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3442)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068158.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 22:43:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,892
            CDSs (total)                      :: 3,805
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 87
            rRNAs                             :: 8, 1, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 55
            CDSs (without protein)            :: 55
            Pseudo Genes (ambiguous residues) :: 0 of 55
            Pseudo Genes (frameshifted)       :: 21 of 55
            Pseudo Genes (incomplete)         :: 28 of 55
            Pseudo Genes (internal stop)      :: 16 of 55
            Pseudo Genes (multiple problems)  :: 8 of 55
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3442
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941466-rid12468953.denovo.165"
                     /strain="01A10CD0081"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            <1..1311
                     /locus_tag="KR231_003749"
     CDS             <1..1311
                     /locus_tag="KR231_003749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015984839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HBH0006070.1"
                     /translation="EEYYYGNTDVNNKRRYYLLDGAKVDDFTKVNNKAINNYHKLLVD
                     QKVGYSVGNPIVFNADDDNLTKLLNDLLGEEFDDTITELYLNASNKGVEWLHPYINRK
                     GEFKYVIIPAEEAIPIWDSKRQRELVAFIRFYYIEDIDGNKIKRVEYYTENDVTYFVE
                     RGNSFVQEFLYDEYGKMTDIQEGHFRINNKEQGWGKVPFISFKNNEKCVSDLTFYKSL
                     IDIYDNNISTLADNLDEIQEVIYVLKEYPGTSLQEFIDNIRYYKSIKVDGGGGVDKLE
                     INIPVEAKKELLDRLEKNIIIFGQGVNPESQNTGDKSGVALKFLYSLLDLKCSKTEKK
                     FKKAIRELLWFVCEYLKISGSKSYDYKTVQITFNHSMIINEAEKIDMAAKSTGIVSDE
                     TIVSNHPWVEDVNDELERLKKQEDTQKEYDDLIPNNQDGVIDET"
     gene            1301..2698
                     /locus_tag="KR231_003750"
     CDS             1301..2698
                     /locus_tag="KR231_003750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015984840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="minor capsid protein"
                     /protein_id="HBH0006071.1"
                     /translation="MKHKDYWRKRFEQLEEAQNNKSVKYYLELEKQYKLAMNSIEKDI
                     LAWYNRFAKNEGISLLEAKKLLNTRELEEFKWSVEEYIRHGKENAINQKWMKELENAS
                     ARVHITRLEALKLQIQQQVEVLYGNELDGIDKLMRHIYTSGYYHAAFNVQQGVNVGWS
                     LMNLDTNRINKVISKPWTSDGLNFSERIWGKHRPALINELHTKLTQSIIRGENPKNLV
                     NDFSKRFNVSKSQAKNLIMTESAFFASASRKDCFNDLDVEKYEIIATLDLKTSNICRE
                     LDGKVFDMKDYQVGVTAPPFHCRCRTTTAPWFEDEEGYRAAKGEDGKTYYVPSSMKYN
                     EWYEKYVKHNSILEIKNSAIIDSIKEDIKNGKYNLNIHDGKQGKHLKEHNNYIEGRSY
                     LTITKEEAQELVNKHAGNGIIKFNRSGEWDKKELIEVDKNIGVNVNNITGEKTLTNKF
                     KIHYSKTGTHIVPAL"
     gene            2713..2913
                     /locus_tag="KR231_003751"
     CDS             2713..2913
                     /locus_tag="KR231_003751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0006072.1"
                     /translation="MKLWEYVGKNVQITCVDKQIIRGKCDGYTQALDNEPEIASISIA
                     RDGYGIEVYENEIESIENINKE"
     gene            2979..>3442
                     /locus_tag="KR231_003752"
     CDS             2979..>3442
                     /locus_tag="KR231_003752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage scaffolding protein"
                     /protein_id="HBH0006073.1"
                     /translation="MDWLKELLEGIKIEDNKIDVASLQKSIEKKIKETTITQEDYTNL
                     ETQLNTANETIKKFEGGMTKEDVENLKTTYETDKKTLEETYKKEIEEKDFNYWLNDAF
                     KSIKCRDEIALKAHLDIEALRNSKDRQKAFEEQINPLKQDKDYLFNATLEGE"
BASE COUNT         1467 a          340 c          652 g          983 t
ORIGIN      
        1 gaagaatact attatggtaa tactgatgta aacaataaga gaagatatta tctcttagat
       61 ggagctaagg ttgatgattt tactaaagtt aataataaag caattaacaa ctaccataag
      121 cttttagttg accaaaaggt aggctatagt gtcggaaatc ccatagtatt taatgcagat
      181 gatgataatc tcactaagct tttaaatgac ttactaggag aagagtttga cgatacaata
      241 acagaactat atctcaatgc tagtaataaa ggggttgaat ggttacatcc atatattaat
      301 agaaaaggtg agtttaaata tgtaataatt ccagctgaag aagcaattcc tatttgggat
      361 agtaaaagac agagggaatt agttgcattt attaggtttt attatattga agatatagat
      421 ggaaataaaa taaaaagagt tgagtactac acagaaaatg atgtaactta ctttgttgaa
      481 agaggtaata gttttgttca agaattttta tatgatgaat atggaaaaat gactgatata
      541 caagaaggtc attttagaat aaataacaaa gaacagggat ggggtaaagt tccatttata
      601 tcttttaaaa ataatgaaaa gtgtgtctca gatttaactt tctataaatc attaatagat
      661 atatatgaca ataatatttc tacactagca gataacttag atgaaataca agaggttatt
      721 tatgtattaa aagaatatcc aggaacaagt ctacaagagt ttatagataa tataagatac
      781 tataaatcaa ttaaagtaga tggtggaggt ggagttgata aactagagat aaatatacca
      841 gttgaagcta aaaaggagct tcttgataga ttagaaaaga atataattat ctttggtcaa
      901 ggagttaatc cagaatctca aaacacaggt gacaaatcgg gtgtagcact taaattttta
      961 tattcattac tggaccttaa atgttctaag actgaaaaga agtttaaaaa agcaattaga
     1021 gagcttttat ggtttgtgtg tgagtattta aagataagtg gtagtaagag ctatgattat
     1081 aaaacagttc aaattacttt taatcactct atgataataa atgaagctga aaagatagat
     1141 atggcagcta aatcaactgg aattgtatca gatgaaacta ttgtttctaa ccatccttgg
     1201 gtcgaggatg taaatgacga acttgagaga cttaaaaaac aggaagatac tcaaaaagag
     1261 tatgatgatt taattcctaa taatcaagat ggtgttatag atgaaacata aagattattg
     1321 gaggaagaga tttgaacaat tagaagaagc tcaaaataac aaaagtgtaa aatattatct
     1381 tgaattagaa aagcaatata aactagctat gaatagtata gaaaaagata tattagcatg
     1441 gtacaacaga tttgccaaaa atgaaggaat atctttatta gaagctaaga aactactaaa
     1501 tacaagagaa ctagaagagt ttaaatggag tgtcgaagaa tatattagac atggtaaaga
     1561 aaatgctata aatcaaaagt ggatgaaaga gttagaaaat gctagtgcaa gagttcatat
     1621 aacaagactt gaagctttaa agttacaaat acagcaacaa gtggaagtgc tttatggaaa
     1681 tgaacttgat ggtattgata aattaatgag acatatttat acaagtggat attatcatgc
     1741 agcttttaat gttcaacaag gagtaaacgt tggttggagt ttaatgaatc ttgatactaa
     1801 tagaataaat aaagttatct ctaaaccatg gactagtgat ggattaaatt ttagtgaaag
     1861 gatttggggc aaacatagac ctgctttaat taatgagtta catactaagc taactcaatc
     1921 aattattaga ggtgaaaatc caaagaacct agtaaatgac ttttctaaga gatttaatgt
     1981 atctaaatca caagctaaga atttgataat gactgaatca gctttctttg catcagcttc
     2041 aagaaaagat tgtttcaatg atttagatgt agagaagtat gagattattg ccacactaga
     2101 cttaaaaaca tcaaatatat gtagagagtt agatggaaaa gtatttgata tgaaggatta
     2161 tcaagttgga gttacagctc caccatttca ttgtcgttgt aggacaacaa cagctccttg
     2221 gtttgaggat gaagaaggtt acagagcagc aaaaggagaa gatggaaaaa catattatgt
     2281 accatctagt atgaagtata atgagtggta tgagaagtat gttaaacata atagtatctt
     2341 agaaataaaa aatagtgcta taatagatag cataaaagaa gatattaaaa atggtaaata
     2401 taatttaaat attcatgatg ggaaacaagg aaaacattta aaagagcata ataattatat
     2461 agaaggaaga agctatttaa ctataacaaa agaagaagct caagaacttg tgaataagca
     2521 tgctggcaat ggaatcataa aatttaatcg aagtggagaa tgggataaaa aagaacttat
     2581 agaagttgat aagaatatag gggtcaatgt taataatatt acgggtgaaa aaactcttac
     2641 aaataagttt aagatacatt attccaaaac tggaacacat atagtaccag ctttataagg
     2701 agggaaaata aaatgaaatt atgggaatat gtagggaaaa atgttcaaat aacttgtgta
     2761 gataagcaaa taataagagg aaagtgtgat ggatatacac aagctttaga taatgaacca
     2821 gaaatagcaa gtatatcaat agctagggat ggttatggaa ttgaagttta tgaaaatgaa
     2881 atagaatcta tcgaaaatat aaataaggaa tgactaagca tgtacttaaa aataagtaga
     2941 tgcttttatt ttgtaaaaaa tgaaaggaga aatttaaaat ggattggtta aaagaattgc
     3001 tagaaggaat aaaaatagag gataacaaga ttgatgtagc ttctttacaa aagtctatag
     3061 aaaagaaaat aaaagagact acaattactc aagaagatta tacaaatctt gaaacacagc
     3121 ttaatacagc taatgaaact attaaaaagt ttgaaggagg tatgacaaaa gaagatgtag
     3181 agaatctaaa aacaacttat gaaactgata agaaaacttt ggaagaaacc tacaaaaaag
     3241 aaattgaaga aaaggacttt aattactggt taaatgatgc ttttaagtct attaaatgta
     3301 gggatgaaat agcgttaaaa gctcatttag atatagaagc actaagaaat agtaaagata
     3361 gacaaaaagc ttttgaagag caaataaacc ctttgaaaca ggataaagat tatttgttta
     3421 atgcaacact agaaggtgaa ga
//
LOCUS       DAEPHU010000163         3380 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 01A10CD0081
            SAMN05941466-rid12468953.denovo.166, whole genome shotgun sequence.
ACCESSION   DAEPHU010000163 DAEPHU010000000
VERSION     DAEPHU010000163.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941466
            Sequence Read Archive: SRR6291087
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 3380)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3380)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068158.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 22:43:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,892
            CDSs (total)                      :: 3,805
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 87
            rRNAs                             :: 8, 1, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 55
            CDSs (without protein)            :: 55
            Pseudo Genes (ambiguous residues) :: 0 of 55
            Pseudo Genes (frameshifted)       :: 21 of 55
            Pseudo Genes (incomplete)         :: 28 of 55
            Pseudo Genes (internal stop)      :: 16 of 55
            Pseudo Genes (multiple problems)  :: 8 of 55
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3380
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941466-rid12468953.denovo.166"
                     /strain="01A10CD0081"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            651..1331
                     /locus_tag="KR231_003753"
     CDS             651..1331
                     /locus_tag="KR231_003753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBH0006074.1"
                     /translation="MQIDVLIIDGDKNSSQELKNFLEGKGINVYLAYNCKDAIIKIFS
                     KKFDLIFLEIILVDGDGWDFCKKVRSITTCPIIHITYINENQSILNALNSGGDDYLIK
                     PLNLEILYAKVKAILRRRDLFLNNNKNNIKLEDYNRASGVIKLENKMIKLTPTENRLL
                     NYFIENAEKTLTIKEIYEHVWMNEYLDDNYSVVVAVSGLRKKIEKDYKNPQKIITIRE
                     VGYYFNKI"
     gene            1778..2062
                     /locus_tag="KR231_003754"
     CDS             1778..2062
                     /locus_tag="KR231_003754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0006075.1"
                     /translation="MLVYNKSFYPNDIFPRLDFSKIKKQLKLIDNDLSDFGSICIIEK
                     EHYTISVNSIGEINVYYDLEYENKVYRIVYEIEKLFKSQVGRFSISTYRN"
     gene            complement(2833..3048)
                     /locus_tag="KR231_003755"
     CDS             complement(2833..3048)
                     /locus_tag="KR231_003755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902968.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBH0006076.1"
                     /translation="MAIVVNLDVMMAKRKISLKELAEKIDITNANLSILKTGKAKAIR
                     FTTLNEICKALDCQPGDILEYVEDEND"
     gene            complement(3059..>3380)
                     /locus_tag="KR231_003756"
     CDS             complement(3059..>3380)
                     /locus_tag="KR231_003756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="DUF2975 domain-containing protein"
                     /protein_id="HBH0006077.1"
                     /translation="RILYFSDYFIVILFLIFIINSTKYSPFVLENVKRFKVMGFCLLI
                     NTIIECINGYNLNTNNIRIFGTDSGGISPLMVISFIFALMCFVIAETFDKAIKIKEDN
                     DLTI"
BASE COUNT         1415 a          287 c          444 g         1234 t
ORIGIN      
        1 ggcattttaa aaaaaacata aatttataat ataaaattgt tttaagctcc ctttccccaa
       61 aataggaaat ttttattagt atttaataat gatttttaat ttttaatata atattaaaga
      121 attatttaag aatatttaat ctctaaagct taaattacaa taatattata aaaataaaag
      181 tgatatattg tgtaataatc gaaattttat actttggtta aaataatttt atatatagtg
      241 cctaatgtat aacctaatgc tcgtagacaa taatgtggat attatcaaat ttatttttat
      301 aatagaaatt ttaatttata tctatattaa attgttaaag atataattat gagaataaaa
      361 aatatagcct tgaattatat aattgtatat gcttatcttt atacagtaaa taaaaaatca
      421 aatgaaatac caaataaagt gtatatctta aaacaattta ctagagatac aaggatgcta
      481 tgtgaatttt gaagtgtgca gtttagataa taaatatata taaataataa agaaaatgga
      541 tttatagtat ttaaaatttc ttataagggt aaaaaatgct attagaaaat gtactaaaaa
      601 tatttttcca attctttata gaaaaataat gatatttagg agagattgta atgcaaattg
      661 atgtattgat aattgatgga gataagaata gttctcaaga gctgaaaaat tttttagaag
      721 gaaaggggat aaatgtctat ttagcatata attgtaaaga tgctattata aaaatattta
      781 gcaagaaatt tgacttaata tttttagaga taattttagt tgatggtgat ggttgggatt
      841 tttgtaaaaa agttagaagt ataactactt gcccaattat tcatataact tatataaatg
      901 aaaatcaaag tattttaaat gctttaaatt ctggaggaga tgattattta ataaagcctt
      961 taaatttaga aatattatat gcgaaagtga aagctatttt aagaagaaga gatttatttt
     1021 taaataataa taaaaataat ataaaactag aagattataa tagagctagt ggagtaataa
     1081 agttagaaaa taaaatgata aagttaactc caacagaaaa tagattatta aattacttta
     1141 tagagaatgc tgaaaagact ctaactatta aggagatata tgaacatgta tggatgaatg
     1201 agtatttaga tgataattat agtgtagtgg ttgctgtgag tggattaaga aagaaaatag
     1261 agaaagatta taaaaatcct caaaaaatta taacgataag agaagtaggg tattacttta
     1321 acaagatata aagctttata aacagaatga atgataaggc atagataata tgttagtata
     1381 ttacaagagt ttttgttcta acgatatatt tgtaaaatta gatttaattt acttaattaa
     1441 attatagcag tagaataaat ataaaaaatg tctgaaatat tatagacatc agtaaaatat
     1501 ataaaactat aatataagtc gtaataataa aacaaatgaa tattaattaa taaaaagata
     1561 gtagctattt ttatatagct attatttttt tattgttgtg gatgaaaata tacttatatt
     1621 ttactaatat acatttaaaa attacaattt aaagcattaa aaaataaatt tgtattttgt
     1681 tttatataaa gtaatttgaa aaatatggaa aaattgatta gtacattatt aattagggta
     1741 taaaatggtg taaatagaat gataaggggt ggatgaaatg cttgtatata ataaaagttt
     1801 ttatcctaat gacatatttc caagattaga tttttcaaaa ataaaaaaac agttaaaatt
     1861 gatagataat gacctgtcag attttggaag catatgtata atagaaaaag aacattatac
     1921 gataagtgta aacagtatag gtgaaataaa tgtgtactat gatttagagt acgaaaataa
     1981 ggtgtataga atagtttatg agattgaaaa gttatttaaa tctcaagttg gaaggtttag
     2041 catatctaca tacagaaatt gataattaaa aaagtagaaa ttaaaaaact taatactaaa
     2101 gatatagata aatatatgag gtaacagcta gagagagttg ttaccctttt taaatactaa
     2161 gtatatatta ttcttattaa ttttttgtaa attcactaaa agaccttttt atagaatatt
     2221 attttctttt tttattaaat aggtaaatca gtaaaaatgc aattccagtt ccaattatta
     2281 ttccaatgat attttctata attaattttt ttaatataaa agtaaataat aaaaatgcta
     2341 tacataaacc taaaatatat cctttaaaat aggttgaaag ttttcttttc atataatcac
     2401 caacttgtat cagatttagt ttacttaatt agagtataac agtgttgtaa cttcaaagag
     2461 tatctaaaag attacaaatg ttagataaaa tcatcaataa tgtaatttat aacacatagc
     2521 tataagctat gcaataatat aaatggaggt ataagtaaat gaaaaagttc catgttttgc
     2581 taacagttta aataaatatt atgtagaaaa gaatgtatat aggaatctgt ggtaaaatta
     2641 tcaatttaaa agtattattt agtgtgatac agttcttata ggtaatggat aacaaataga
     2701 taaaggaaca gtttctttct tagaacatat tttgttatga ctttaaacaa agttaatatt
     2761 aatgtcaata atatagtaaa agaataaaaa tcatatagta taataaaaaa gagtgtttct
     2821 aaacactctt ttttaatcat tttcatcttc tacatattca agtatatcac ctggctgaca
     2881 gtctaaagct ttgcaaattt cgtttagagt ggtaaatcta atagcttttg cttttccagt
     2941 ttttaaaatt gataaatttg catttgtaat atctattttt tctgccaatt ctttaagtga
     3001 tatttttctt tttgccatca ttacatctag gttaactact attgccataa catcacctct
     3061 atatcgttaa atcattatct tcttttattt ttatagcttt atcaaatgtt tctgcaatta
     3121 caaagcacat tagtgcaaat ataaaagaga taaccataag tggtgagata ccgccactat
     3181 cagttccaaa aattcttata ttattagtat ttaaattata accattgata cattcaatta
     3241 tagtgtttat caataaacaa aatcccatta ctttaaacct ttttacattt tcaagtacga
     3301 atggggaata cttagtacta ttaattataa atatcaagaa taagatgact ataaagtagt
     3361 cagaaaaata tagtattctt
//
LOCUS       DAEPHU010000164         3318 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 01A10CD0081
            SAMN05941466-rid12468953.denovo.167, whole genome shotgun sequence.
ACCESSION   DAEPHU010000164 DAEPHU010000000
VERSION     DAEPHU010000164.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941466
            Sequence Read Archive: SRR6291087
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 3318)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3318)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068158.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 22:43:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,892
            CDSs (total)                      :: 3,805
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 87
            rRNAs                             :: 8, 1, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 55
            CDSs (without protein)            :: 55
            Pseudo Genes (ambiguous residues) :: 0 of 55
            Pseudo Genes (frameshifted)       :: 21 of 55
            Pseudo Genes (incomplete)         :: 28 of 55
            Pseudo Genes (internal stop)      :: 16 of 55
            Pseudo Genes (multiple problems)  :: 8 of 55
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3318
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941466-rid12468953.denovo.167"
                     /strain="01A10CD0081"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            <1..871
                     /locus_tag="KR231_003757"
     CDS             <1..871
                     /locus_tag="KR231_003757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="glycerophosphodiester phosphodiesterase"
                     /protein_id="HBH0006078.1"
                     /translation="VFNLVLILLISYIESVAFSSHINGMFNTSFSFYTTAIAHRAGAE
                     MAPENTLAAIEEASHAKADYAEIDVQETKDGELIVLHDSNFKRTTGVDKNVWDVNYNE
                     VKTYDAGSFYYYGKGYYDEKFVGEKIPTLKEMIKYSKGKVKLLIEIKLNGHEKGDVVK
                     KVVQLIKENNFENQCIVASMDKTILQKVKKLDENLLTCYFMAIAYGDFSKLNYVDIYG
                     IESTFVNKTVVEKIHKMNKKIFVWTVNSDSLIEKMLDLNVDSIITDNPYLIESAIYWK
                     KNGFISQVSDYLF"
     gene            1193..1777
                     /locus_tag="KR231_003758"
     CDS             1193..1777
                     /locus_tag="KR231_003758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar O-acetyltransferase"
                     /protein_id="HBH0006079.1"
                     /translation="MTEREKMLAGELYDCGDIELLTQWHKAKDLVRDYNQTDSLDLEK
                     KEKILNELLGGKGKNLWITAPYYVDYGNNIYFGNNCEVNMNCTFLDDNKIIIGDNALI
                     APNVQIYTAFHPTNAGDRFGNAKEDGSFEFCKTQTAPVTIGDNVWIGGGAIIMPGVTI
                     GDNVVIGAGSIVTKDIPSNMIAYGNPCRIIRENK"
     gene            complement(2880..3056)
                     /locus_tag="KR231_003759"
     CDS             complement(2880..3056)
                     /locus_tag="KR231_003759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0006080.1"
                     /translation="MFIGEIDKCTHILTAYISSSYDYCNFLDTQLDDFISEYGETVVE
                     TCLHQVLLLVSRYN"
BASE COUNT         1299 a          312 c          498 g         1209 t
ORIGIN      
        1 tgtttttaat ttagtattaa tattattgat ttcttatata gagtcagttg cattttcttc
       61 acatataaat ggtatgttta atacgtcatt ttcattttat acaacagcaa ttgctcatag
      121 agcaggagct gaaatggctc cagagaatac tttggcagca atagaagaag cttcacatgc
      181 taaagctgat tatgcagaaa tagatgttca agaaactaaa gatggagaac ttattgtact
      241 tcatgattca aactttaaga gaactacagg agtagataaa aatgtttggg atgtaaatta
      301 taatgaagta aagacatatg atgcgggaag cttttattat tatggaaaag gttattatga
      361 tgaaaagttt gttggggaaa agataccaac actcaaagaa atgataaaat attctaaagg
      421 taaggtgaaa ttattaatag aaataaaact taatggacat gaaaagggag acgtagtaaa
      481 aaaagttgtt cagttaatta aagaaaataa ttttgaaaat caatgtatag ttgcatctat
      541 ggataaaact atattacaaa aagtaaaaaa actggatgag aatttactga catgctattt
      601 tatggcaatt gcatatggtg atttttcaaa gttaaattat gttgatatat atggaattga
      661 atcaactttt gttaataaaa cagtagtaga aaagattcat aaaatgaaca aaaaaatctt
      721 cgtttggact gttaatagtg acagtttaat tgagaaaatg cttgacctaa atgtagatag
      781 tattattaca gataatccat accttataga gagtgcaatt tattggaaga aaaatggatt
      841 tattagtcaa gtgtcagatt atttatttta aatattctat aattgtatta tccagtaaaa
      901 gagatattat taaaatcaat aatatctctt tttaacataa ataaggttgt taaattaagg
      961 ctattcttat aaaaattgtg tttatcagat ataaataagg aataaaagta aaaaaattgc
     1021 tatgacatta ttacaattaa aagagtttta atatgataga gaggtagatt gtcaactgta
     1081 tatttaataa attttattat ttattagatt ttatataagt aaaatatata gatatataaa
     1141 tcttatgcta gaatatatat gaaaaacaat atagatttgg agggttaaaa gcatgacaga
     1201 gcgagaaaaa atgttggcag gagaacttta cgattgtggt gatattgagt tgttaactca
     1261 atggcataaa gcaaaagacc tagtaagaga ttataaccaa acagattcct tggatttgga
     1321 aaaaaaagaa aaaatattaa atgagttact tggtggtaag ggtaaaaact tatggattac
     1381 tgcaccgtat tatgtagatt atggaaataa tatttatttt ggaaataatt gtgaagtcaa
     1441 tatgaattgt acgtttttag atgataataa aattatcatt ggggataatg cactaatcgc
     1501 accaaacgta caaatatata ctgcatttca tccaactaat gctggtgata gatttggtaa
     1561 tgccaaagaa gatggttcat ttgaattttg taaaactcaa acagctccag ttactattgg
     1621 agataatgtt tggattggcg ggggtgctat tatcatgcca ggtgttacta ttggagataa
     1681 tgtagttata ggtgcaggaa gtattgttac aaaagatatt ccaagtaata tgattgcata
     1741 cggaaatcca tgccgtatta ttcgagaaaa taaataaagt taaattttct tgcaaaatct
     1801 caaaaaacac ctttcttact ttatacatag ggtattttct aatactttca catccatatt
     1861 catttgttaa atttttgtgg aatgtagttt ttatcacttc tatcttacat ttccaccatt
     1921 tttttataaa agtcattcct ttatagattt atttataata gtatatattc tatttgatgt
     1981 ttgaataagc acttattttt aagtaaaata ctaacttcta ggttagtatt ttactatagt
     2041 atgatgatta agtaagaata aaatactata atacataaag cttaataaat ataattttta
     2101 ttttacttag atattttctt ttgattagta atcaaaagtg gttataattt ttttaattaa
     2161 taagagtaac atttatttta tgaaagagga ttatattaat atatatttaa ataggaaaaa
     2221 ttgtaaaaag cataaaaata atataattaa ttaatgagat aaaagtggat aaaaatattg
     2281 ggagtttaat ttttgtgaaa ttaaaaatat taaagctaat ctacaaatat agaatatatt
     2341 ctaagacgaa tttttataat tactaaataa aataaattaa tcaatatagt tttttaatat
     2401 aaacaaaaaa taaaaaactt atataaataa aatgcttgtt tttcttgtat tatttatata
     2461 aatattgaaa tttgtctagt tatacgtttt tattgaccag ttatgcagtt gatattgaat
     2521 attctaaata ttggtgttat tttataggtg gtttaaacat attaggggga ttttatatat
     2581 gatttgtatg atttatagag aatgtataaa atagtaaagg tttagagcca tgtttagtgg
     2641 attgcagaat atgcatatag aatgattctt gtaaattaag ttagacatag gaaatatata
     2701 atttgtattg gatgattaat tttatggtgt atgcttttaa cttctataat gggaaagtaa
     2761 agatgtactc ccaatacatc tttactttag cagaagttat agttacttat aaagtacaaa
     2821 aaattatata tttattagag tagataaatc taaaaaggtt tttctagaaa aatttagttt
     2881 taattgtatc tacttactaa taataagact tgatgtaagc aggtttcaac taccgtttct
     2941 ccatattctg atataaaatc atctaactgt gtatctaaaa aattacaata atcatatgaa
     3001 ctactgatgt aagcagttag tatatgtgta catttgtcta tttctccaat aaacatatta
     3061 tccatccccc taaaaaattt agtaaaaata aaaagtcgca ttctattagt caattaacat
     3121 aatttataaa attttttagt actagtttct ataacttaac tccttaaggt taaatattcc
     3181 cagttttacc aatttagttt tattctacaa gtatataata ctagaagatg cttcattatt
     3241 caacatgctt gtttgagaat agaaaatatt ctaaaattat aattgttttt aaaaataaga
     3301 ttcaagataa ataaagtt
//
LOCUS       DAEPHU010000165         3054 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 01A10CD0081
            SAMN05941466-rid12468953.denovo.168, whole genome shotgun sequence.
ACCESSION   DAEPHU010000165 DAEPHU010000000
VERSION     DAEPHU010000165.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941466
            Sequence Read Archive: SRR6291087
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 3054)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3054)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068158.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 22:43:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,892
            CDSs (total)                      :: 3,805
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 87
            rRNAs                             :: 8, 1, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 55
            CDSs (without protein)            :: 55
            Pseudo Genes (ambiguous residues) :: 0 of 55
            Pseudo Genes (frameshifted)       :: 21 of 55
            Pseudo Genes (incomplete)         :: 28 of 55
            Pseudo Genes (internal stop)      :: 16 of 55
            Pseudo Genes (multiple problems)  :: 8 of 55
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3054
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941466-rid12468953.denovo.168"
                     /strain="01A10CD0081"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            complement(213..821)
                     /locus_tag="KR231_003760"
     CDS             complement(213..821)
                     /locus_tag="KR231_003760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-3-methyladenine glycosylase"
                     /protein_id="HBH0006081.1"
                     /translation="MEKDFFRKNGIDLAKSILGKYLIRKYENKVIVTKIIETEAYMGV
                     NDKGAHVYGNKKTDRTKPLYLDGGHIYVYLIYGMYNCLNLSANIENVPECVLIRGVEP
                     ITSLDEISMNRYNKAYTELSKYQVKNITNGPGKLCKALKIDRSLNSKSIMGEELYISD
                     FYYDDKGKKVFSKDELDIKTSKRINIDYAEEAKDFLWRFYIE"
     gene            complement(930..>3054)
                     /locus_tag="KR231_003761"
     CDS             complement(930..>3054)
                     /locus_tag="KR231_003761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="PAS domain-containing sensor histidine kinase"
                     /protein_id="HBH0006082.1"
                     /translation="GVIYLLLCNHTYYVYVYSLNNRVVYPYYELDSINKKLSKKSEQL
                     GKINLAIEKDMIIQRTLKNYIDQRKELLRQALDTIPNVWIVTDYDFNISYTNNKFKDE
                     FSKDMNNYYKILTFIKEDEKVAEKLKKFDNDISIIDKLVELNDKIYLLSLSNNKDESN
                     YLISLNDITNEIKIDEEIRNINKDYENIILNIPSPILVRSAEGGIKKNKVISINKKYE
                     KSFKCVSSDLVDMTLEQYFETFNIDFFDNREFKRLNLTQEKKAEIVSYNDTANCIVNF
                     VMSDSEGEEHVEEVRVGDYWSDNKLFKLLTFRDITKEINILRTVNEQKIIYEKLLDVI
                     PEAIFLEDLSTSRVLYTNRAFRELFGISSDVLGVTTQKYRNILVKKYINNLNIGEREK
                     SIHIVNENNHIKEVKMISRTLYFGQKRSRVRIIKDLSVQRESERLKKALIKQRQYDQM
                     KMEFYANISHELKTPLNNIYSSVQLIENLYKKGKIIDFQDILKEHIKITKQNMFRLLR
                     LIDNIINISQVKSDIYKIKAVNFDIIDITERIVTSISSYAKSKGIDLIFDTDEETVMV
                     GLDPESIERIILNILSNAIKFTLEGGEILVGIYKKDETVEIIIKDTGVGIDKEKLNDI
                     FNRFKQIENSGISNEFGSGIGLCLTKSLIEIQNGKIYIDSKVGEGTNVKVIFPIKEVV
                     EEVYDNSNYNDNIEKFEIEFFDIYK"
BASE COUNT          976 a          494 c          238 g         1346 t
ORIGIN      
        1 taatttttaa taaaatacac aaaaaaatta atttttatag ctcatttcgc caaaatatat
       61 ctttctttat atcatgaaaa taattataaa tttattaaat atgtttgtaa ttctataaag
      121 ttatttttat caaactaaaa attctataaa aaaataagat acatacctat aaaatacctt
      181 cctatagata catatcttac ctatataaaa acttattcta tataaaaacg ccataaaaaa
      241 tcttttgctt cttctgcata atctatattt atacgtttac tagtttttat atctaactca
      301 tctttactaa atactttttt tcctttatca tcataataaa aatcacttat atataattct
      361 tcacccatta tactcttact atttagactt ctatctattt ttaaagcttt gcaaagtttt
      421 cctggtccgt tagtaatatt ttttacttga tatttactca actcagtgta agctttgttg
      481 tatctattca tagatatctc atctaaagaa gttataggct ctacccctct tattaataca
      541 cactctggca cattttctat atttgcagat aaattcaagc aattatacat accataaatt
      601 aaataaacat atatatgtcc accatctaaa tataatggct tagttctatc tgtcttttta
      661 ttgccatata catgtgctcc tttatcattt acacccatgt atgcttctgt ctctatgatt
      721 ttggtaacaa ttactttatt ttcatatttc cttattagat atttacctaa tattgatttg
      781 gctaaatcaa ttccattttt tctaaaaaaa tccttttcca aaatttcacc tcataaaatt
      841 tatttaaaac gcatcaaata caactaaagt aataaataaa attaactctt attaatgtga
      901 tatatataaa caataaattt agacatttat tatttatata tatcaaaaaa ttctatctca
      961 aacttttcaa tattatcatt gtaatttgaa ttatcatata cttcttcaac aacctcttta
     1021 attgggaata taacttttac attagttcct tctcctacct tactatctat gtaaatcttc
     1081 ccattttgaa tttcaatcaa tgattttgta aggcataaac ctataccact tccaaattca
     1141 tttgatatac cactgttttc aatttgttta aatcgattaa atatatcatt taatttttct
     1201 ttgtctatgc ccactccagt atcttttata attatctcta ctgtttcgtc ttttttatat
     1261 atacctacaa ggatttctcc tccttctaaa gtaaatttta tagcatttga taatatattt
     1321 agtattattc tttctatcga ttctgggtca agccctacca taacagtttc ttcatctgta
     1381 tcaaaaatta aatctattcc tttagactta gcataactac taatagatgt aactattctt
     1441 tctgttatgt caataatatc aaaattaact gctttaatct tatatatgtc tgacttaact
     1501 tgagaaatat ttattatatt atctattaat ctcaataatc taaacatatt ttgtttagtt
     1561 atttttatat gttcttttag tatatcctga aaatcaatta tttttccttt tttataaagg
     1621 ttttcaataa gttgaactga actatatata ttatttaaag gtgtcttaag ttcatgagat
     1681 atattagcat aaaactccat cttcatttgg tcatactgtc tttgttttat taatgctttt
     1741 ttaagtcttt cagactctct ttgcacactt aaatctttaa taattctcac tctacttctt
     1801 ttctgtccaa agtataatgt tcttgatatc atttttactt ctttaatgtg attattttca
     1861 tttactatat ggatactctt ctctctttct cctatattta aattgtttat gtattttttt
     1921 actaatatat ttctatattt ttgtgttgta actcctaata catcactaga aattccgaac
     1981 aactctctaa aggctctatt tgtatatagt actcttgatg tacttaaatc ctcaagaaaa
     2041 atagcctctg gtataacatc cagtaatttt tcatatatta ttttttgttc atttactgtt
     2101 ctaagaatat ttatctcttt agttatatct ctaaatgtaa gcaatttaaa gagtttatta
     2161 tctgaccaat agtctccaac tctaacttct tcaacatgct cttcaccttc tgagtcagac
     2221 atcacaaaat taactataca gtttgctgtg tcattgtaac ttactatttc agctttcttt
     2281 tcttgtgtta gatttaatct tttaaattcc ctattgtcaa agaaatctat gttaaaagtt
     2341 tcaaaatatt gttctaatgt catatcgact aaatcacttg aaacacattt aaaactcttt
     2401 tcatattttt tatttatact tattacctta ttcttcttta tgccaccttc agcacttctt
     2461 acaagtatag gagatggaat atttagtata atgttttcat agtctttatt tatatttctt
     2521 atttcttcat ctattttgat ttcatttgta atatcattta aacttattaa gtaattgctt
     2581 tcatctttat tattacttaa acttaacaaa taaattttat catttaactc taccagttta
     2641 tcaattatac ttatatcgtt atcaaatttc ttcaattttt cagcaacttt ttcatcttcc
     2701 tttataaaag ttaatatttt ataataatta ttcatatcct ttgaaaattc atctttaaat
     2761 ttattatttg tgtaacttat attaaaatca tagtctgtta ctatccatac atttggtatt
     2821 gtatccagag cttgtctaag taattctttt ctctggtcta tgtagttttt taatgttctt
     2881 tgtataatca tatccttttc tattgctaaa tttatctttc ctaattgctc tgacttttta
     2941 cttaattttt tattgattga atcaagttca taatatggat acactactct attattaaga
     3001 ctgtatacat atacataata agtatggtta cataatagta aatatattac tcct
//
LOCUS       DAEPHU010000166         2909 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 01A10CD0081
            SAMN05941466-rid12468953.denovo.169, whole genome shotgun sequence.
ACCESSION   DAEPHU010000166 DAEPHU010000000
VERSION     DAEPHU010000166.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941466
            Sequence Read Archive: SRR6291087
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 2909)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2909)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068158.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 22:43:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,892
            CDSs (total)                      :: 3,805
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 87
            rRNAs                             :: 8, 1, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 55
            CDSs (without protein)            :: 55
            Pseudo Genes (ambiguous residues) :: 0 of 55
            Pseudo Genes (frameshifted)       :: 21 of 55
            Pseudo Genes (incomplete)         :: 28 of 55
            Pseudo Genes (internal stop)      :: 16 of 55
            Pseudo Genes (multiple problems)  :: 8 of 55
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2909
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941466-rid12468953.denovo.169"
                     /strain="01A10CD0081"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            complement(272..829)
                     /locus_tag="KR231_003762"
     CDS             complement(272..829)
                     /locus_tag="KR231_003762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBH0006083.1"
                     /translation="MRVSREIVIQATSDIVNKDGLNKVSLKVIAEKLGIRTPSLYNHI
                     ESLDDLLLEVAHKGMREMNSQMIKAAIGNFGDTAIKCISIAYFNFIISNPGVYETIQW
                     ATWHGNNETLEIFDEYKSLLEKLILSCNLNTKNTGEVLNLIMSVLHGYSTLQLGKSFL
                     SKEEAIKGLVDSIDTVLLGIHKKYD"
     gene            1087..1785
                     /locus_tag="KR231_003763"
     CDS             1087..1785
                     /locus_tag="KR231_003763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HBH0006084.1"
                     /translation="MEKKYFEIHGVPSILWGNPSSKLYIYIHGQCGNKEEAEAFANIA
                     VPHECQVLSVDLPEHGERKREKNSFNPWHVVPELVSIMEYAKCHWNQISLYANSIGAW
                     FSMLSFEKENLRECIFVSPILDMQQLISNMMLWANVSEEQLKHELIIPTSFGHTLSWE
                     YLQYVKQHPITQWNIPTKILYGKHDELTEIGVVEKFVEKFNCNLTIVENGKHWFNTPQ
                     ELNSLYEWLNTLVK"
BASE COUNT         1092 a          369 c          300 g         1148 t
ORIGIN      
        1 tatactttaa aatccttact aatttgaact ataatttatt ttttgatatc ctttttgatt
       61 aacatataaa ttaattcaat tattaaacat aaactatgtt gtttctcttt atatctcttc
      121 tttgtaaaca atattgggca tttgaaaata aatattctta aaatatactg ttctcctgtt
      181 gattttcctt tggtacaaat gataaaaatt taatttacat gccccataat gaagtgttca
      241 ataaataagt taaaataatt tatttacctc cttaatcata ttttttatga atacctaata
      301 acacagtatc aatagaatcg actaaacctt ttatagcttc ttctttactc aaaaatgatt
      361 tcccaagttg caaagtcgaa taaccatgaa gtacactcat tattaagttt aatacttcac
      421 ctgtattctt tgtatttaga ttacaagaaa gaataagttt ttctaataag gatttatatt
      481 catcaaagat ttctaatgtt tcattatttc catgccaagt agcccactga attgtttcat
      541 aaacaccagg attagaaatt ataaaattaa agtatgctat acttatacac tttatagctg
      601 tatctccaaa atttccaata gccgccttta tcatttgact attcatctct ctcattcctt
      661 tatgagctac ttcaagtaat aaatcatcta gactttctat atgattgtac aaagatggtg
      721 tacgtattcc tagcttttct gcaataactt ttaaagaaac tttgttaagc ccatctttat
      781 taactatatc tgatgtagct tgtataacta tttctctact aacacgcatg attttccctc
      841 tttcatttaa aattaattac tttattagtt taactaatct aattagtttc gtcaattatt
      901 gtaatttata aaattcttta tactattata aaatcttgac agtttaatta taatttaata
      961 taatactaat taaattagtt ttaatactaa tataattagt attatattaa attctatatt
     1021 acaacattat tttatagttt gattaattta ataatcacta atatatcaaa ctgaaaggag
     1081 atttttatgg aaaaaaaata tttcgaaatt catggagttc cttcaatcct ttggggaaat
     1141 ccttcaagta aattatatat ttacatacat ggacaatgtg gcaataaaga ggaggctgaa
     1201 gcttttgcta atattgcagt tccacatgag tgtcaagttt taagtgttga tttgcctgaa
     1261 catggagaac gtaaaagaga aaaaaattca tttaacccat ggcatgttgt tccagaatta
     1321 gtatctatta tggaatatgc aaagtgccac tggaatcaaa tttcgttata tgcaaatagc
     1381 attggagcat ggtttagtat gttaagcttt gaaaaagaga acttaagaga gtgtattttt
     1441 gtatctccaa ttctagatat gcaacagctc atttcaaata tgatgctctg ggcaaatgta
     1501 tcagaagaac agcttaaaca tgaactaatt atcccaactt catttgggca tactctttca
     1561 tgggaatatc tacaatatgt aaaacaacat cctatcactc aatggaatat accaacaaaa
     1621 atattatatg gtaaacatga tgaacttact gaaatcggtg ttgtagagaa atttgtagaa
     1681 aagtttaatt gcaaccttac tattgtagaa aatggcaaac attggtttaa cacaccacaa
     1741 gaattaaatt cattatatga atggttaaat actttagtta aataaaaaat aattatatta
     1801 ttaatatgat taaattattt ataaatgtta tttaattaat tttattttag cattattaaa
     1861 ataactacat aaagaataaa ttagttatta ttaaagaaat taaaagtata tagagtatta
     1921 ataatttttt aataattagt tattatagaa aaaagaggga tataatattg tctccctctc
     1981 tttcttctgt aatattatat aatttttatt tatcactctc aataaattat agttatctac
     2041 aaaattcaat ctttaataca ttattaatat attgtgatat taatattaca gtattaaata
     2101 aaatctaata aaattaacta taaaatatct attatataaa tatccactct tatgtttgaa
     2161 atccgtcata tagttttatc cttcttatct tttatatcaa taactttttt taataaaatt
     2221 gacaaaacta aagtaaaaaa ccttattgat aatgaaacaa atgatactat aagttctgat
     2281 attatagtaa ttgcatataa atagacatca taaaaataat ataatattgt cactataaaa
     2341 ttaaatgtaa aaatctcaaa tctaactaaa tacacatata ggtatttttt aagtttttag
     2401 gtatttcttc tgaaaatgat ttattgattg ataccaattt acataatctt tttaatataa
     2461 acaatgatac aatatatggg acagcacata tgtatatagc tacttatatt acagttggca
     2521 tattcgtatt tgtaatgctt ataccaattt taaaatacac catcagtact aatagtatta
     2581 aaataatcta taataaagtt aaaattattc caattagtac aatattattt aatattttac
     2641 aactcatatc cttttttata taaatttacc accttataca ttcttatttt tagtgtatat
     2701 tacaatggtt ttatatatta tatcaatatt ttattattga aattcaataa attatatatt
     2761 ataatcaata atatacttta tataaaggag atgatatttt atgattacaa aattttttag
     2821 taatatatta tcagtatttc tatattttct attatcactt ttaggagttg ctggtataat
     2881 attcttatgt atgataccta tgtttttat
//
LOCUS       DAEPHU010000167         2828 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 01A10CD0081
            SAMN05941466-rid12468953.denovo.170, whole genome shotgun sequence.
ACCESSION   DAEPHU010000167 DAEPHU010000000
VERSION     DAEPHU010000167.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941466
            Sequence Read Archive: SRR6291087
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 2828)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2828)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068158.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 22:43:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,892
            CDSs (total)                      :: 3,805
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 87
            rRNAs                             :: 8, 1, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 55
            CDSs (without protein)            :: 55
            Pseudo Genes (ambiguous residues) :: 0 of 55
            Pseudo Genes (frameshifted)       :: 21 of 55
            Pseudo Genes (incomplete)         :: 28 of 55
            Pseudo Genes (internal stop)      :: 16 of 55
            Pseudo Genes (multiple problems)  :: 8 of 55
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2828
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941466-rid12468953.denovo.170"
                     /strain="01A10CD0081"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            complement(<1..587)
                     /locus_tag="KR231_003764"
     CDS             complement(<1..587)
                     /locus_tag="KR231_003764"
                     /EC_number="5.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid racemase"
                     /protein_id="HBH0006085.1"
                     /translation="MNEKLIGILAGMGPRSTAPFVDLIIDECQSQYGAKYDDEFPKMM
                     IYSLPTPFYIDRPINHELMKETIIDGLQKLESTGVNFIAMPCNSAHIYFKELKESINI
                     PILNIVEETVKKLPTISQKVTLFSTSSTFESTIYQNGIIHNGHEFIFKDEWQIKLNNL
                     IQNIKMDKENPHNIDIWNKLIEDVKNESIENIVIA"
     gene            complement(749..1966)
                     /locus_tag="KR231_003765"
     CDS             complement(749..1966)
                     /locus_tag="KR231_003765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallo-hydrolase"
                     /protein_id="HBH0006086.1"
                     /translation="MLGKKCMDYLQTLGKISSTTNGLTRLILTQEHKKSIDLISSWME
                     GLNLDIEIDDIGNVIGTYKSSFPNAPTLVVASHQDSVKCGGIFDGMLGIIVPLVGLEE
                     AKHNNRSYPFNIKLIAFAEEEGTRFETSLMGSKVFAGTFKEELLKSVDENGITLEEAV
                     TKFGFNTKNLTNLHPRKDVDAYLEFHIEQGPVLENESLPAGIVSSITGFKSFKISVNG
                     KSGHAGTLPMNMRLDAGCCACECVLAIEKVAKTTADLVATVGKMNFYPSSSNVVPERA
                     EFTLDVRSCSQEILDNSVEKIFNEISHICENRKLNYTSELAFENVPVPCSNKITKIIE
                     KSFIDLNLNPFYIYSGAGHDAQEMDNITDIGMVFIRCAGGVSHNPNESVSVDDLDTAV
                     KIFLKILDNLDLK"
     gene            complement(2157..2570)
                     /locus_tag="KR231_003766"
     CDS             complement(2157..2570)
                     /locus_tag="KR231_003766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905693.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBH0006087.1"
                     /translation="MELEITEKIEKQDEDTIFQGLLKYNLARLEDKNPVDLGIYIRDK
                     AGKIVAGFIGVTHGNWLSIKYLWVSEKLRYKGTGSQLLYKAEKIAKERGCKYVFLDTF
                     SFQAPKFYEKFGYHKVFSLENYPLTGKRYYFRKIL"
BASE COUNT          996 a          421 c          314 g         1097 t
ORIGIN      
        1 caagcaatta ctatattttc tatagattca tttttaacat cttcgataag tttattccaa
       61 atatcaatat tgtgtggatt ttctttatcc atttttatat tttgaataag attgtttaat
      121 tttatttgcc attcatcttt aaatataaat tcatgtccat tatgtattat accattctgg
      181 taaattgtag actcaaaagt tgaactagtc gaaaaaagag ttactttttg tgagatagta
      241 ggtaattttt taactgtttc ttctacaata tttaatattg gtatattaat agactctttt
      301 aattctttaa agtatatatg tgctgaattg catggcattg caataaaatt tacaccagtt
      361 gattcaagct tttgtaatcc atcaattata gtttctttca taagttcatg atttattgga
      421 cggtcaatat aaaatggggt aggtaatgaa tatatcatca tctttggaaa ttcatcatca
      481 tattttgctc catattgaga ttgacactca tcaataatta aatcaacaaa aggggctgtt
      541 gaccttggac ccattccagc caaaatacca attaattttt cattcataaa aattatctcc
      601 tttatatata aatatattta tgtataaaat aaaaatctat aaaagcataa aattatattt
      661 tataatagat tatattgtac acttatataa tataaatata aagtgatttt ttagattata
      721 tattttaata tactttctta tataagaatt attttaaatc aagattatct agtattttta
      781 aaaatatttt tacagcagta tccaagtcat ctacagaaac actttcatta ggattatgac
      841 ttacgccccc agcgcatctt ataaatacca taccaatatc agttatatta tccatttcct
      901 gagcatcatg gccagcacca ctataaatat aaaaaggatt aagatttaaa tctataaaac
      961 ttttttctat gatttttgtt attttattag aacatggtac aggaacattt tcaaaagcaa
     1021 gttcacttgt ataattaagt tttctatttt cacatatatg tgatatttca ttaaatatct
     1081 tttctacaga attatcaaga atttcttgtg aacaagagcg tacatcaaga gtaaattcag
     1141 ctctttcagg taccacattt gatgaagatg gatagaaatt catctttcct acagtagcaa
     1201 ccaaatcagc agtcgtttta gctacttttt cgatagctaa tacacattca caggcacaac
     1261 atccagcatc aagtctcata ttcattggaa gtgtaccagc atgtccagac ttaccattta
     1321 ctgatatctt aaaactttta aatcctgtaa tacttgatac aattccagca ggaagagatt
     1381 cattttctaa aacaggaccc tgctcaatat gaaattctaa atatgcatct acatcttttc
     1441 taggatgcaa atttgttaag ttttttgtat taaatccaaa ctttgttaca gcttcttcaa
     1501 gtgtaattcc attttcatca acagatttaa gaagttcctc tttaaaagta ccagcaaaaa
     1561 ctttacttcc cattaaagaa gtttcaaatc tagttccttc ctcttcagcg aaagcaatta
     1621 gcttaatatt gaaaggataa gacctattat tgtgttttgc ttcttcaaga ccaactagag
     1681 gcactattat acctaacata ccatcaaata tacctccaca ctttacacta tcttgatgag
     1741 atgcaactac taatgtggga gcatttggaa agcttgattt atatgtacct ataacgtttc
     1801 caatgtcatc aatttcaata tcaagattta aaccttccat ccatgaacta attaaatcaa
     1861 tagatttttt atgttcttga gtcaagataa gtcttgtaag accatttgtt gttgaactta
     1921 tttttcctaa tgtttgtaga taatccatac atttttttcc taacatattt acctcctaaa
     1981 aatataattt ttatttaagc taagattagc ttttatactt ataatttttg aactttcaaa
     2041 taattttgta tgtatagtaa aatactattt tagtattaat aatgatataa aaatataaag
     2101 tctgtagacg aagagcagaa gttttaagtt aaaaatataa aatatgattt ttattattat
     2161 agtatttttc taaaataata tctctttcca gttagaggat aattttcaag tgaaaatact
     2221 ttatggtatc caaatttctc ataaaattta ggtgcttgaa aactgaatgt atctaaaaaa
     2281 acatatttac aacctcgttc tttagcaatt ttttcagcct tatataaaag ttgacttcca
     2341 gtacctttat atctaagctt ctcactaacc cataagtatt ttatagaaag ccaattacca
     2401 tgagtaacac ctataaaacc tgcaacaatt ttacctgctt tatctcgaat atatattcct
     2461 aaatccactg ggtttttatc ttcaagtcta gcaagattat attttaataa tccttgaaaa
     2521 atagtatctt catcttgttt ttctattttt tctgtaattt ctaattccat atttgaactt
     2581 tctccttgta taatcttttg tatattggta ttttttaata aaatcagtag aaagaatata
     2641 gtttaacatt attctaatag gcatttatgc taatgtcaaa ctaataatac ttattcttaa
     2701 ttttatattg ttgatattaa atttttttaa ataaaaatgt agtttaagtt atataaaaag
     2761 aaatcatcaa taaatttagt aaacctaaat tgttgaatat taaaataagt taatttaata
     2821 cataaaaa
//
LOCUS       DAEPHU010000168         2687 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 01A10CD0081
            SAMN05941466-rid12468953.denovo.171, whole genome shotgun sequence.
ACCESSION   DAEPHU010000168 DAEPHU010000000
VERSION     DAEPHU010000168.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941466
            Sequence Read Archive: SRR6291087
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 2687)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2687)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068158.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 22:43:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,892
            CDSs (total)                      :: 3,805
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 87
            rRNAs                             :: 8, 1, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 55
            CDSs (without protein)            :: 55
            Pseudo Genes (ambiguous residues) :: 0 of 55
            Pseudo Genes (frameshifted)       :: 21 of 55
            Pseudo Genes (incomplete)         :: 28 of 55
            Pseudo Genes (internal stop)      :: 16 of 55
            Pseudo Genes (multiple problems)  :: 8 of 55
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2687
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941466-rid12468953.denovo.171"
                     /strain="01A10CD0081"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            complement(227..1039)
                     /locus_tag="KR231_003767"
     CDS             complement(227..1039)
                     /locus_tag="KR231_003767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HBH0006088.1"
                     /translation="MFSIGMFSKINKITTKTLRYYEDIGLLKPEYVDEFTKYRYYTTE
                     QLPKLHQIITLKQMGLSLAEIKKAVENPEEVENILMNKEKEMLDVIKSEEYKIIKLRN
                     YLMNLKGEVNMNDVIIKSLPKVKVASMRKVLKGYDELFNLFPNVMAEEMMKTGCTCAV
                     PDYCFNIYHDGEYRETDMDVEMCQAINDLKEDTDILKFKELDAVENAVCILHNGPYST
                     LGKTYADAFKWIEDNKYKVVGNPRESYIDGIWNKESEEDWLTEVQIPVKRML"
     gene            complement(1115..2533)
                     /locus_tag="KR231_003768"
     CDS             complement(1115..2533)
                     /locus_tag="KR231_003768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="potassium/proton antiporter"
                     /protein_id="HBH0006089.1"
                     /translation="MTELMIISGLVLLICITSSKVLYKFGVPILLIFILLGMLFGSDG
                     MVGIYFDNYELTKQLCSIGLIFIMFFGGFGTNWNMAKPVAIPSILMSSLGVIITAGVT
                     GMFCHMVIGTSLLEGLLIGAIAASTDAASVFAVLRSQKLNLKGSLASLLEVESGSNDP
                     IAYMLTLILLTLMNNSGVELIAPMVIKQIAFGLAIGFILAKLSVYILRHSNFEIEGFY
                     TIFITAIAILSYAFSEYLGGNGYLSVYISGIIIGNSRIPLKKSLVHFFDGISWIMQIM
                     LFFMLGLLSFPSKLPNVFGIAMAISIFMIVIARPLATFIVLAKFKFSNKEKLFISWVG
                     LRGAASVVFAIYAVTQGVAIENDIFHIIFFIALLSVGIQGSLIPTVARKLDLVDDNTP
                     VLKTFNDYDGEISSKLIEVNVDEGNKWANKSIIDSNIPDDILIVMIKRKEQVLIPKGS
                     TIIKTGDILVLSGDRIEELIQL"
BASE COUNT          942 a          485 c          275 g          985 t
ORIGIN      
        1 atacaattat ttataaagtc tttaataaaa atttataaat agagcatctt tagaaaacta
       61 ttataataaa aaaataagag gctgtctaaa aatatagata agcctttttt cataatcgta
      121 attataaaaa tatacttgat ttcatatgaa aaagagtgtc tcataaacta aaatgtttac
      181 tttgagacac cacctttttt attcttattt atactttgta gacatattat aacatgcgtt
      241 tcactggtat ctgaacttct gtcaaccagt cttcttcact ctctttattc catataccat
      301 ctatataaga ttctctagga tttccaacca ctttatattt attgtcctct atccatttaa
      361 atgcatctgc gtaagttttt cctaatgttg aatatggacc attgtgtaat atacaaactg
      421 cattttcaac tgcatctaat tctttaaatt ttaatatatc cgtatcttcc tttaaatcat
      481 ttatagcttg acacatttca acatccatat cagtctctct atattcacca tcatgatata
      541 tattaaaaca ataatcagga actgcacatg tacaccctgt tttcatcatt tcttcagcca
      601 ttacatttgg aaatagatta aaaagttcat catacccctt taacactttt ctcatagaag
      661 caactttaac ttttggtaaa gacttaataa ttacatcatt catattgact tctcctttca
      721 aattcataag gtaattacgt agtttaatta ttttatattc ttcactttta attacatcca
      781 acatttcttt ttctttattc attaaaatat tttcaacttc ttcaggattt tctacagctt
      841 tttttatctc agctaatgat aaacccattt gttttaaagt tattatctga tgtaatttag
      901 gtaattgctc tgttgtataa tacctatatt ttgtaaattc atctacatat tctggtttta
      961 acaaccctat atcttcataa taccttaatg tctttgtagt tattttattt attttagaaa
     1021 acattcctat agaaaacatc tcatcacctg cgcattagat ttgattaatt taagtttaaa
     1081 ctttcccctt aggttaaagt caatacaaaa taaattataa ttgtattaat tcttcaattc
     1141 tatctccact caataccaaa atatcccctg tttttataat ggttgaacct ttaggtatta
     1201 aaacctgttc ctttcttttt atcataacta ttaatatatc gtctggtata ttagaatcta
     1261 ttatactctt attagcccat ttattaccct catcaacatt tacttcgata agtttagagc
     1321 taatttctcc atcataatca ttaaatgttt ttaatacagg tgtattatca tcaactaaat
     1381 ccaactttct ggctacagtt ggtatcaatg aaccttgtat tcctactgaa agcaacgcta
     1441 taaaaaatat tatatggaat atgtcattct ctatggctac tccttgagta acagcataaa
     1501 ttgcaaaaac tactgaagcc gcacctctaa gacctaccca cgatatgaat aatttttctt
     1561 tatttgagaa tttaaatttt gctagaacta taaatgttgc taatggtctt gcaataacta
     1621 tcatgaatat agatatggcc attgctatac caaatacatt tggtaactta gaagggaaag
     1681 ataacaatcc taacataaag aataacatta tttgcataat ccatgaaatt ccatcaaaga
     1741 aatgaaccaa acttttttta agaggtatcc tactatttcc tataataata cctgaaatgt
     1801 aaacacttaa atatccattt cctccaagat actcgctaaa tgcataagaa agtattgcaa
     1861 tagctgttat aaatatagta taaaatcctt ctatctcgaa gtttgaatgt cttaaaatat
     1921 aaacagataa ttttgctagt ataaatccta tagctaaccc aaaagctatt tgttttatta
     1981 ccattggtgc aataagttct accccagaat tattcatcaa tgtcaaaaga attagtgtca
     2041 acatatacgc tattgggtca ttacttccac tttcaacttc taataatgat gcaagtgaac
     2101 cctttaagtt tagtttttga gaacgcaaca cagcaaacac agatgcagca tctgttgaag
     2161 ctgcaattgc cccaattaat aaaccttcaa gtaaactagt tcctattacc atgtggcaaa
     2221 acatacctgt aaccccagcc gtaattatta cacccagtga agacattaat atagaaggta
     2281 tagcaacagg tttagccata ttccagtttg ttccaaaccc tccaaaaaac attataaata
     2341 ttagtccaat agaacataat tgttttgtca gttcatagtt atcaaaatag attcctacca
     2401 tcccatcaga cccaaataac atccctagta agataaaaat caataatatt ggtactccaa
     2461 atttatacaa taccttgcta gaagttatac aaatcaatag tactaaccca cttataatca
     2521 ttaattctgt catagcatca actccatttc atataaattt tgtagattaa tttacatcta
     2581 caattttatt acttattcaa atataacatg acataaattt tataagttat ggtacataaa
     2641 gttcaacaaa aatttcacaa tacattaaaa tgtgagtgtt atactta
//
LOCUS       DAEPHU010000169         2681 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 01A10CD0081
            SAMN05941466-rid12468953.denovo.172, whole genome shotgun sequence.
ACCESSION   DAEPHU010000169 DAEPHU010000000
VERSION     DAEPHU010000169.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941466
            Sequence Read Archive: SRR6291087
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 2681)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2681)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068158.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 22:43:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,892
            CDSs (total)                      :: 3,805
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 87
            rRNAs                             :: 8, 1, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 55
            CDSs (without protein)            :: 55
            Pseudo Genes (ambiguous residues) :: 0 of 55
            Pseudo Genes (frameshifted)       :: 21 of 55
            Pseudo Genes (incomplete)         :: 28 of 55
            Pseudo Genes (internal stop)      :: 16 of 55
            Pseudo Genes (multiple problems)  :: 8 of 55
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2681
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941466-rid12468953.denovo.172"
                     /strain="01A10CD0081"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            <1..217
                     /locus_tag="KR231_003769"
     CDS             <1..217
                     /locus_tag="KR231_003769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015984839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HBH0006090.1"
                     /translation="TFNHSMIINEAEKIDMAAKSTGIVSDETIVSNHPWVEDVNDELE
                     RLKKQEDTQKEYDDLIPNNQDGVIDET"
     gene            207..1700
                     /locus_tag="KR231_003770"
     CDS             207..1700
                     /locus_tag="KR231_003770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="minor capsid protein"
                     /protein_id="HBH0006091.1"
                     /translation="MKHKDYWRKRFEQLEEAQNNKSVKYYLELEKQYKLAMNSIEKDI
                     LAWYNRFAKNEGISLLEAKKLLNTRELEEFKWSVEEYIKYGKENAINQKWMKELENAS
                     ARVHITRLEALKLQIQQQVEVLYGNELDGIDKLMRDIYTSGYYHTAFNVQQGVNVGWS
                     LMSLDTNRINKIISKPWAIDGLNFSERIWGKYRPTLVNELHTKLTQSIIRGENPKNLV
                     NDFAKRFNVSKSQAKNLIMTESAFFASASRKDCFSDLEVEKYEIIATLDLRTSNICRE
                     LDGKIFDMKDYQVGITAPPFHCRCRTTTAPWFEDEEGYRAARGEDGKTYYVPSSMKYN
                     EWYEKYVKNNSKQTGAKYTKGDIEWNIRREEEAELYYDNIRNRKDDISKISKNTNWSE
                     KSIGQIKNHIFYNTHIMRDGTRRMLDSDYSMSVAWQRLINGTYEDIDILLLKHEYLES
                     IFEKKYNISNLEAHRMTEKKHDWYKELIKQKGEFEEDDCLNELIRKE"
     gene            1666..1908
                     /locus_tag="KR231_003771"
     CDS             1666..1908
                     /locus_tag="KR231_003771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0006092.1"
                     /translation="MIVLMNLLEKNNEYVIYSYGYEENKLDGRIKIYLDDFYNYEIIK
                     ESKDEHISKSATLKAISKLIKAAKNNDLKKEMSYQC"
     gene            1979..2173
                     /locus_tag="KR231_003772"
     CDS             1979..2173
                     /locus_tag="KR231_003772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015981492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0006093.1"
                     /translation="MYILTQVIAVVCVVQIFINCIANVNVGILCNKLKEKNEANIDKV
                     SDEILKRVGEELNESLDKSL"
     gene            2218..>2681
                     /locus_tag="KR231_003773"
     CDS             2218..>2681
                     /locus_tag="KR231_003773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage scaffolding protein"
                     /protein_id="HBH0006094.1"
                     /translation="MDWLKELLEGIKIENNKIDVVSLQKSIEKKIKETTITQEDYTNL
                     ETQLNTANETIKKFEGGMTKEDVENLKTTYETDKKTLEETYKKEIEEKDFNYWLGDAF
                     KSVKCRDEIALKAHLDIEALRNSKDRQKAFEEQINPLKQDKDYLFNATLEGE"
BASE COUNT         1172 a          251 c          485 g          773 t
ORIGIN      
        1 tacttttaat cactctatga taataaatga agctgaaaag atagatatgg cagctaaatc
       61 aactggaatt gtatcagatg aaactattgt ttctaaccat ccttgggtcg aggatgttaa
      121 tgacgaactt gagagactta aaaaacagga agatactcaa aaagagtatg atgatttaat
      181 tcctaataat caagatggtg ttatagatga aacataaaga ttattggaga aagagatttg
      241 aacaattaga agaagctcaa aataacaaaa gtgtaaaata ttatcttgaa ttagaaaagc
      301 aatataaact agctatgaat agtatagaaa aagatatatt agcatggtac aacagatttg
      361 ccaaaaatga aggaatatct ttattagaag ctaagaaact actaaataca agagaactag
      421 aagagtttaa atggagtgtt gaagaatata ttaaatatgg taaagaaaat gctataaatc
      481 aaaagtggat gaaagagtta gaaaatgcta gtgcaagagt tcatataaca aggcttgaag
      541 ctttaaagtt acaaatacag caacaagtag aagttttata tggaaatgaa cttgatggta
      601 ttgataaact aatgagagat atttatacaa gtggatacta tcatacagct tttaatgttc
      661 aacaaggagt aaacgttggt tggagtttaa tgagtcttga tactaataga ataaataaaa
      721 ttatctctaa accatgggca atagatggat taaactttag tgaaagaatt tggggtaagt
      781 atagacctac tttagtaaat gaactacata ctaagctaac tcaatcaatt attagaggtg
      841 aaaatccaaa aaatttagta aatgactttg ctaagagatt taatgtatct aaatcacaag
      901 ctaagaattt gataatgact gaatcagctt tctttgcatc agcaagtaga aaagattgtt
      961 ttagtgattt agaagtagag aaatatgaga ttattgctac attagattta agaacttcaa
     1021 atatatgcag agagttagat ggaaaaatat ttgatatgaa agattatcaa gttggaataa
     1081 cagctccacc atttcattgt cgttgtagga caacaacagc tccttggttc gaggatgaag
     1141 aaggctatag agcagcaaga ggagaagatg gaaaaacata ttatgtacca tctagtatga
     1201 agtataatga gtggtatgag aagtatgtta aaaataatag taaacaaact ggtgcaaaat
     1261 atactaaagg tgatatcgag tggaatataa gaagagaaga agaagcagaa ctatattacg
     1321 ataatattag aaatagaaaa gatgatattt ccaaaatatc aaagaataca aattggtcag
     1381 aaaaaagtat aggtcaaatt aaaaatcata ttttctacaa tactcatata atgagagatg
     1441 gaactagacg tatgttggat tctgactata gtatgtcagt tgcttggcaa agacttataa
     1501 atggtacata cgaagatatt gatattctct tattaaaaca tgaatacctt gaaagtatat
     1561 ttgagaaaaa gtataatata agtaacttag aagcccatag aatgactgag aaaaagcatg
     1621 attggtataa agaattaatt aaacagaaag gagagtttga agaagatgat tgtcttaatg
     1681 aacttattag aaaagaataa tgaatatgtt atatatagtt atggatatga agaaaataag
     1741 cttgatggaa gaataaaaat atatttagat gatttttata attatgaaat aataaaagag
     1801 tcaaaagatg aacatataag taaatcagca acgttaaaag ctatttctaa acttataaaa
     1861 gctgctaaaa ataacgattt gaaaaaagaa atgagttatc aatgttagaa gcacttactg
     1921 aacaataaat tagtaggtgc ttttattatg taaaagttta aaaaagtagg tgattttaat
     1981 gtatatatta actcaagtta tagctgtagt ttgtgtagta caaatcttta ttaattgtat
     2041 tgctaatgtc aatgtaggta ttctttgcaa taaattaaaa gaaaaaaatg aagctaatat
     2101 agataaagtt tctgatgaaa ttctaaagag agtaggagaa gaattaaatg aatcactaga
     2161 caaaagtctt taaagacttt ttttattgtg taaaaaatga aaggagatat ttaaaagatg
     2221 gattggttaa aagaattgct agaaggaata aaaatagaaa ataacaaaat tgatgtagtt
     2281 tctcttcaaa aatctataga aaagaaaata aaagagacta caattactca agaagattat
     2341 acaaatcttg aaacacagct taatacagct aatgaaacta ttaaaaagtt tgaaggaggt
     2401 atgacaaaag aagatgtaga gaatctaaaa acaacttatg aaactgataa gaaaactttg
     2461 gaagaaactt acaaaaaaga aattgaagaa aaagatttta attactggtt aggtgatgct
     2521 tttaaatctg ttaaatgtag agatgaaata gcattaaaag ctcatttaga tatagaagca
     2581 ctaagaaata gtaaagacag acaaaaagct tttgaagagc aaataaatcc tttgaaacag
     2641 gataaagatt atttgtttaa tgcaacacta gaaggtgaag a
//
LOCUS       DAEPHU010000170         2626 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 01A10CD0081
            SAMN05941466-rid12468953.denovo.173, whole genome shotgun sequence.
ACCESSION   DAEPHU010000170 DAEPHU010000000
VERSION     DAEPHU010000170.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941466
            Sequence Read Archive: SRR6291087
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 2626)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2626)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068158.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 22:43:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,892
            CDSs (total)                      :: 3,805
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 87
            rRNAs                             :: 8, 1, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 55
            CDSs (without protein)            :: 55
            Pseudo Genes (ambiguous residues) :: 0 of 55
            Pseudo Genes (frameshifted)       :: 21 of 55
            Pseudo Genes (incomplete)         :: 28 of 55
            Pseudo Genes (internal stop)      :: 16 of 55
            Pseudo Genes (multiple problems)  :: 8 of 55
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2626
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941466-rid12468953.denovo.173"
                     /strain="01A10CD0081"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            complement(720..1349)
                     /locus_tag="KR231_003774"
     CDS             complement(720..1349)
                     /locus_tag="KR231_003774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine amidotransferase"
                     /protein_id="HBH0006095.1"
                     /translation="MKNRKVYMYVFDTMSDWEVAYLTAELNTGRYFKKGLKPLKVITV
                     GIDKNPIITMGGLKVLPEITVDEFNMESKDLLILPGGNTWLSMNHEIILEKVKEALIQ
                     DSIVAAICGATLGLAKKGLLDVRNHTSNDLEFLKMVIPNYSGEKYYKTESVVSDENLV
                     TASGIAPLEFTFQVLKLLDVFESEALNSWLNLYKTHDSKYFFELMNCNK"
     gene            complement(1428..2390)
                     /locus_tag="KR231_003775"
     CDS             complement(1428..2390)
                     /locus_tag="KR231_003775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017561613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WYL domain-containing protein"
                     /protein_id="HBH0006096.1"
                     /translation="MAKIDNMMSILWMLNSDKKITAKQIAEKLEINIRTVYRYIDVLS
                     ASGVPIISDTGHNGGYSLLNNFTKAPLFFDIEEQKSLLHAALFAKKEGYFLDEALDKS
                     ILKLKMYSNQNQEDILTNHLRALEVIKPIGKVSIESVLKKLENSILKELSVEINYHAG
                     RKAKSKYRIINPYGIVHWNNNWYVVAFCNMRNEVRSFRVDRISEIIETSNTFNRPTEF
                     SASEFFIKGIIPEIKDEQNIIQLVVEGSIDSLDSLSQHWFLGHYLKERTPNKIIFMLE
                     EEVICKYIPNILLPYRKTIQVIEPLSLRKKIIEDLLELIDYYQI"
BASE COUNT          879 a          410 c          276 g         1061 t
ORIGIN      
        1 atattttata aaagatttta taataaacat tacaatacag tactaaatta gtttatttca
       61 tctatcatct caatcatatc atttactaac tattattcta atgagcatat aacattgaaa
      121 tttataatta tacaacctaa atgcctccca atgtaccctc aaaaacatca tttcctgtaa
      181 ctgaagtata attggtatat tttatcactg aaataaaaaa acactagtca ataaagacta
      241 gtattttcaa gtattttatc attctttttt taattattgg agacgaatca tcagaataat
      301 gcccataatt tatctatatg caaattctaa atttaaaata aagtttcaga tgaatttact
      361 attctatgct atgatacaac agaaaaaact gaaatctatg agtggtagct tcatataatc
      421 ctagttccta cagtaatcaa aactgaggtt tattctatat gtaactaatg ataaatttta
      481 ttataggagt tattagctct atttgtgtta ctataagtag taattatata tatgataatt
      541 ttttaacact tttctgttgg ctatatagaa agtggtttag aatttaaatt taaataaaat
      601 ttaaattcac caaaaagaaa tctatattag aaaccactac tctattccac cagattgtaa
      661 ttttttgttc tttatatcac aatgctatac catattaaat tgaaaaataa attttaaatt
      721 tatttgttac aattcattaa ttcaaaaaaa tattttgagt catgagtttt gtaaagattt
      781 agccatgaat ttaatgcttc tgattcaaaa acatctaaaa gtttcaatac ttgaaacgta
      841 aattccaacg gagcgattcc tgaagccgta actaaatttt catcactaac tacagattcc
      901 gttttataat atttttctcc agagtaattt ggtattacca ttttaagaaa ctctaagtca
      961 ttacttgtat gatttctaac atctaatagc ccttttttag ctaggcctaa tgtagctcca
     1021 catatggctg caactataga atcttgtatt aaagcttctt taactttttc taatattatc
     1081 tcatgattca tggataacca agtatttccc cctggcaaaa ttaataaatc cttactttcc
     1141 atattaaact catcaactgt aatttcaggt aaaactttta acccacccat tgttataata
     1201 ggatttttat caattcctac agtaattact tttagtggct ttaatccttt tttaaaatat
     1261 cttcctgtat ttaattcagc agttaaatat gccacttccc aatctgacat agtatcaaat
     1321 acatacatat atacttttct atttttcatc ttttttactc cttatgtaat taatttatat
     1381 atctaattat aaaataactt aactgacata ttcagtcagt taagctatta aatttgataa
     1441 taatcaatta attctagtaa atcttcaatt attttcttcc taaggcttag tggttcaatt
     1501 acttgtattg tctttctata aggtaaaagt atatttggta tgtacttgca tattacttcc
     1561 tcttcgagca taaatattat tttattaggt gttctttctt tcaagtagtg ccctaaaaac
     1621 caatgttggc ttaaactatc taaagaatct atactccctt ctacaactaa ttgaattata
     1681 ttttgttcat cttttatttc aggtataatt ccttttataa aaaattcact tgctgaaaat
     1741 tctgtcggtc tgttaaatgt atttgatgtt tctatgattt cactaatcct atccactctg
     1801 aaactacgta cctcatttct catattacaa aatgcaacta cgtaccaatt attattccag
     1861 tgaacaattc catatggatt tataattcta tattttgatt ttgctttacg acctgcatga
     1921 tagttgattt ctacagatag ctcctttaat atactattct ccaatttttt aagtactgat
     1981 tctatagaca ctttcccaat tggttttatt acttcaaggg ctcttaagtg gtttgttaaa
     2041 atatcttctt ggttttgatt tgaatacatt tttaacttta atatcgattt atctaatgct
     2101 tcgtctaaga agtatccttc ttttttagca aatagagctg catgaagtag agatttttgc
     2161 tcttctatat caaaaaaaag aggtgcttta gtaaaattat ttaaaaggct atacccacca
     2221 ttatgacctg tatctgaaat tataggtact ccactcgcag aaagtacatc aatatatcgg
     2281 tacactgttc ttatatttat ttctaatttt tcagctatct gttttgctgt aatttttttg
     2341 tcagagttta acatccacag tatagacatc atattgtcaa ttttagccat gtagtttcac
     2401 ctctttctat ttgttatata aagttattat ataacttttt gattgatttt ttacaaaaaa
     2461 acattagtaa actgctaata atttatacta agatttattt caaatattta tagatagtct
     2521 ttttctatag ttaagttatc cattaaatta catagtagta tatccatttt agttgatata
     2581 ttttcagcta cctcccttga atattattac aataagtcta aatctt
//
LOCUS       DAEPHU010000171         2533 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 01A10CD0081
            SAMN05941466-rid12468953.denovo.174, whole genome shotgun sequence.
ACCESSION   DAEPHU010000171 DAEPHU010000000
VERSION     DAEPHU010000171.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941466
            Sequence Read Archive: SRR6291087
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 2533)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2533)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068158.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 22:43:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,892
            CDSs (total)                      :: 3,805
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 87
            rRNAs                             :: 8, 1, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 55
            CDSs (without protein)            :: 55
            Pseudo Genes (ambiguous residues) :: 0 of 55
            Pseudo Genes (frameshifted)       :: 21 of 55
            Pseudo Genes (incomplete)         :: 28 of 55
            Pseudo Genes (internal stop)      :: 16 of 55
            Pseudo Genes (multiple problems)  :: 8 of 55
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2533
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941466-rid12468953.denovo.174"
                     /strain="01A10CD0081"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            636..2432
                     /locus_tag="KR231_003776"
     CDS             636..2432
                     /locus_tag="KR231_003776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002594337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
                     /protein_id="HBH0006097.1"
                     /translation="MKPTMEILTKLQENSKKNHDEVFTRLYRYLLRPDIYYVAYQHLY
                     SNKGAGTKGVTDDTADGFSEIYIENIIEALKNEMYQPKPVRRTYIKKSNGKMRPLGLP
                     VFTDKLIQEAIRMILEAIYEPIFSDYSHGFRPARSCHTALAQIKKEFTGARWFIEGDI
                     KGCFDNINHAVLVEIINQKIKDARFLKLIRSFLKAGYMEDWKYHKTYSGCPQGGIISP
                     ILANIYLNELDRHVMKIKKEFDVATKARYTPEYTKLVGLRQRLHNKIKNSNGIEREKL
                     IEEYKSATAQMLKLPAKQCDDKKIKYVRYADDFLIAVNGNRQDCEKIKQELTEFISTT
                     LKMELSQEKTLITHSNTPARFLGYDVRVRRDQQIKPKGKFKTRSMNNKVELSIPFKDK
                     IEKFLFSNGIVKQRSDNGKLEPIHRPQLLNRTDLEIVTIYNAELRGICNYYGLASNFN
                     KLIYFNYLMEYSCLKTLAGKHRSKVSKIRAMYKDGTGKWAIPYETKTVIKKMYFANYA
                     DCKGKKFTDIVPQTAKNYSHDVTTLESRLKAKICEVCGCTESDRYEIHHVNKVKNLKG
                     KSEWEKIMIAKRRKTIVVCHKCHMAIHHGEKK"
BASE COUNT          971 a          433 c          528 g          601 t
ORIGIN      
        1 ttagaagtag attaaagaaa gggggacaga aaaaaaaggc actaccccgt aagataacac
       61 gggaaaccac ctgcctaacc gaaaggtgaa aactgtacgg gaaaatagca cggcaggaaa
      121 gcagaaagtt gttcaaagac aatagagcac gactgaactg caaggttaag tgaatatgag
      181 gataaaacta gatttgttga atgtgagttc caaacctctg ttacgtgtgg acacaggaaa
      241 cttgtctgaa acctgtggta tgagtaacgc tgaaaataaa tgcctttcag tgggttatca
      301 attaactcat acggtacgct ggagaaccag tagtaacgga acgaaagcat atccgacaat
      361 tcacaccagc ctactacttt cgtcaactgg agattaccta aaccagaatg cctacaatgg
      421 ctatgtgtaa tgctcttgta gtgataaatc acaaggctat gctaagtgag atgacgctga
      481 aaatctggca aggtaacgga gctttcatag tagtctgaga accctgaaaa gacagggaaa
      541 gccgtaaaat cggatacggg aaaaccgttc acatggcgaa ggaaagcagt cttagcgaat
      601 taaaattaga aattgattag ggaggaaaac ctcaaatgaa accaacaatg gagattttaa
      661 ccaaattaca ggaaaattca aaaaagaacc atgatgaagt atttacaagg ctctatcgat
      721 atttactccg tccagatata tactatgttg catatcaaca cctctactcc aacaaaggag
      781 caggaacaaa gggtgtaaca gacgacacag cggacggttt tagcgaaata tatattgaaa
      841 atatcattga agccttaaaa aatgaaatgt atcaaccaaa accagtaaga cgtacataca
      901 tcaaaaaatc aaatggcaaa atgcgtccct taggactgcc tgtctttact gataagctga
      961 tacaggaagc aatacgcatg atattagaag caatctatga gcctattttt tcagactact
     1021 ctcacggttt ccgaccagca agaagttgtc atactgctct tgctcaaata aaaaaagaat
     1081 ttacaggagc acgctggttt atagagggcg acataaaagg gtgctttgat aacatcaatc
     1141 atgcggtact tgtggaaatt atcaatcaga aaattaaaga tgcacgtttt ctgaaactca
     1201 ttcgttcatt cttaaaggca ggttatatgg aagattggaa ataccacaaa acatatagcg
     1261 gttgccctca aggtggcatc atttcgccta ttcttgcgaa tatctacctt aatgaattag
     1321 accgtcacgt aatgaagata aagaaagagt ttgatgtggc aacaaaggca cgttatacac
     1381 cagaatatac aaaactggta ggactacgcc aaagattaca caacaaaatt aaaaatagca
     1441 acggtataga aagagaaaag ctgattgaag aatataaatc tgcaacggct caaatgctta
     1501 aactaccagc gaagcaatgt gacgacaaga aaataaaata tgtgcgttac gctgatgatt
     1561 tcctaatagc tgtgaatggc aatcgacagg attgtgagaa gattaagcaa gaacttacag
     1621 aatttataag taccacatta aaaatggaac ttagtcaaga aaaaactctg attacacaca
     1681 gtaatactcc tgctcgtttt ctcggatatg atgtcagagt acgccgtgac cagcagatta
     1741 aaccaaaagg aaaattcaaa acccgttcta tgaataacaa ggtggaattg agtattccat
     1801 tcaaagacaa gatagagaaa tttttatttt caaatggaat tgtaaagcag aggtcagaca
     1861 atgggaaatt agaacctata caccgaccac aactgcttaa taggacagat ttggaaatag
     1921 tgactattta taatgcagaa ttaagaggta tctgtaatta ttatgggttg gcaagcaatt
     1981 ttaacaagct aatctatttc aattatctta tggaatatag ctgtttgaaa acacttgcag
     2041 gaaagcaccg ttccaaagtt tctaaaatta gagctatgta taaagacggt acaggcaaat
     2101 gggctattcc ttatgaaact aaaacagtaa taaagaaaat gtattttgcg aattatgctg
     2161 actgcaaagg aaagaagttt actgatattg ttccacaaac agctaaaaat tattcccatg
     2221 acgtaacaac attagaaagc cgattaaagg cgaagatatg tgaagtatgt gggtgtacgg
     2281 aaagtgacag atacgaaatt catcatgtaa acaaggttaa aaaccttaaa ggaaaatcag
     2341 aatgggaaaa gataatgata gccaaaagac ggaaaacaat cgtggtatgc cacaagtgtc
     2401 acatggctat acatcatggc gaaaagaaat aacctgtaac ggagcaaaga tggagagccg
     2461 tgtgcattga gaaatgcaag cacggttcgg ggagaggact gcacaaacct accctagaaa
     2521 taaggaaagg cgg
//
LOCUS       DAEPHU010000172         2451 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 01A10CD0081
            SAMN05941466-rid12468953.denovo.175, whole genome shotgun sequence.
ACCESSION   DAEPHU010000172 DAEPHU010000000
VERSION     DAEPHU010000172.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941466
            Sequence Read Archive: SRR6291087
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 2451)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2451)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068158.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 22:43:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,892
            CDSs (total)                      :: 3,805
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 87
            rRNAs                             :: 8, 1, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 55
            CDSs (without protein)            :: 55
            Pseudo Genes (ambiguous residues) :: 0 of 55
            Pseudo Genes (frameshifted)       :: 21 of 55
            Pseudo Genes (incomplete)         :: 28 of 55
            Pseudo Genes (internal stop)      :: 16 of 55
            Pseudo Genes (multiple problems)  :: 8 of 55
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2451
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941466-rid12468953.denovo.175"
                     /strain="01A10CD0081"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            545..1987
                     /locus_tag="KR231_003777"
     CDS             545..1987
                     /locus_tag="KR231_003777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding repeat-containing protein"
                     /protein_id="HBH0006098.1"
                     /translation="MRTIRRVLALGLTLAIFLINVPNVDALTSDTIKGNNIYETAGLI
                     ADKKSYDTAIMVNMDNSIADGLSASGLAGAVDAPILLAQKNKIPNETKQRLKNVKKIY
                     IIGKELSISKSVETELKNTGAQVTRLGGDDRIKTSYSVAKEVNGIKKVDEVILTNAYK
                     GEADTISAAPVSVRDIAPIVLTDGKSVPFSTSNVKTYAVGGSISMSTSLVNKTNAKRL
                     GGSDRYDTNKKVIKEFYPDASEFYLSDGYDLVNALTGSTIAKENPIVLVSESSDKSIL
                     AGADKITRLGSISDSVYNKCVSAAQNNGDSSTKGESPMKNETSILGQPTASLEACLKW
                     AKSKKANDLFIELIPILYDTAVQEGVNPVLAVAQSAKETGFCNFGGVLDASFKNPCGL
                     KTSVGGSDTDKNAHSRFDTWEEGILAQIQHLCLYAGQDGYPLSNPVDPRHEKSLFGKA
                     KTVESLSNNWAGGQYGQDLVRMMGEIEATK"
     gene            2029..2382
                     /locus_tag="KR231_003778"
     CDS             2029..2382
                     /locus_tag="KR231_003778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0006099.1"
                     /translation="MKKSNIFSIIFPTVIMVLMFLTFATDIFNIPDIQSKSIFVVGMV
                     LIFPISFLIQGIICVLNKTNWILSLIVSLVTYIVLMYIFLNDSAYIYVLLYTAFYMIG
                     HITAKLYYKIKTFKN"
BASE COUNT          957 a          257 c          421 g          816 t
ORIGIN      
        1 ataaaaaaat gttagaatta aattaaaagt gaaaagtaga ttgatatata aatagtaaat
       61 acttaattaa aaaaagataa tgatagcaat aattattgtt accaagaatc tactacttca
      121 agtgttacct taggtattta agttgatagt ggtttgcacg taataaactt gatgtaatat
      181 atattcttaa taatatcgat aaaagattta cttaaaaata atatagatta tgtaaacata
      241 taatctattt attgtataca ataaaatttc attttgtaaa acagtgaatt aaatatgtaa
      301 tatagatatc gatttttatt acaaattgtt actaaatata ggtacattag aacaaaaatc
      361 tagtaaattg taactaaaat gtaaattttt cctttaatct atacaatatt atggaaactt
      421 tttgtaattt atgatataat aacaaatata taattattaa attataataa atgactatag
      481 cgtagatgta atactatgtt atagtcattt ttgaattaaa cttgatatat caagggggaa
      541 gaatatgaga acaattagaa gagttttagc attaggttta acattagcta tatttctaat
      601 aaatgtacct aatgtagatg cattaacatc agatacaatt aaaggtaaca atatatatga
      661 gacggctgga ttaatagcag ataaaaagag ttatgataca gcaattatgg taaatatgga
      721 taattctata gcagatggtc tttcagcaag tggtcttgca ggtgctgttg atgctccaat
      781 tttgcttgca caaaaaaata agataccaaa tgaaacaaaa caaagattaa aaaatgttaa
      841 aaagatatac ataataggta aagaattatc aataagtaag tcagtagaaa ctgaactaaa
      901 aaacacaggg gcacaggtaa ctagattggg tggagatgac agaataaaga ctagttatag
      961 tgttgctaaa gaggtaaatg gtatcaaaaa agttgatgaa gtgatattaa ctaatgcata
     1021 taaaggagaa gcagatacaa taagtgctgc acctgtatca gtaagagata tagctcctat
     1081 agtacttaca gatggaaaga gtgtaccttt ttcaacaagc aatgtaaaaa catatgcagt
     1141 aggtgggagt atatcaatga gcactagttt agttaataaa actaatgcta aaagacttgg
     1201 tggttcagat agatatgata caaataagaa agttataaaa gagttttatc cagatgcatc
     1261 agaattttat ttgagtgatg gatatgattt agtaaatgca cttacaggtt ctacaattgc
     1321 taaggaaaat ccaattgtat tggtgtcaga aagtagtgat aagtctatat tagcaggagc
     1381 agataagatt actagattag gttcaataag tgacagtgtg tataataagt gtgtttctgc
     1441 tgcacaaaat aatggcgatt cgtctacaaa aggtgagtca cctatgaaaa atgagacaag
     1501 catattaggt cagccaacag ctagtttaga agcgtgctta aaatgggcaa aatctaaaaa
     1561 agctaatgat ttatttatag agttaatacc aatattatat gatactgctg ttcaggaagg
     1621 tgttaatcct gttttggcag tagctcaatc tgcaaaagaa actggttttt gtaattttgg
     1681 tggagtatta gatgcatcat ttaagaatcc ttgtggactt aaaacttctg taggaggttc
     1741 tgatactgat aagaatgccc attcaagatt tgatacttgg gaagaaggaa tattagctca
     1801 aattcaacat ttatgcttat atgcaggaca agatggttac ccactttcaa atccagtaga
     1861 ccctagacat gaaaaatctt tatttggtaa ggctaaaaca gttgaaagtt tatctaataa
     1921 ttgggctgga ggtcaatatg gacaagattt agtaagaatg atgggagaaa ttgaggcaac
     1981 aaaataattg aagattatca aatatccaat aaataaggat tgattattat gaaaaagagt
     2041 aatattttta gtatcatatt tcctacagtc ataatggtgc taatgttttt aacttttgct
     2101 acagatatat ttaatattcc agatattcaa tctaaaagta tttttgttgt gggaatggtt
     2161 ttgatttttc caatttcttt tttgatacaa gggataattt gtgtattaaa taagactaat
     2221 tggattttat ctcttattgt gtctttagta acttatatag tattaatgta tatattttta
     2281 aatgattctg catatatata tgttttactt tatacagctt tttatatgat tggacatata
     2341 acagctaaac tctattacaa aattaagact tttaaaaatt aaattgaagt atataaaagt
     2401 aacattagga gaagtatcct taatgatttt ctaaaatcag aaataggtgc t
//
LOCUS       DAEPHU010000173         2336 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 01A10CD0081
            SAMN05941466-rid12468953.denovo.176, whole genome shotgun sequence.
ACCESSION   DAEPHU010000173 DAEPHU010000000
VERSION     DAEPHU010000173.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941466
            Sequence Read Archive: SRR6291087
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 2336)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2336)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068158.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 22:43:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,892
            CDSs (total)                      :: 3,805
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 87
            rRNAs                             :: 8, 1, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 55
            CDSs (without protein)            :: 55
            Pseudo Genes (ambiguous residues) :: 0 of 55
            Pseudo Genes (frameshifted)       :: 21 of 55
            Pseudo Genes (incomplete)         :: 28 of 55
            Pseudo Genes (internal stop)      :: 16 of 55
            Pseudo Genes (multiple problems)  :: 8 of 55
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2336
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941466-rid12468953.denovo.176"
                     /strain="01A10CD0081"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            316..1935
                     /locus_tag="KR231_003779"
     CDS             316..1935
                     /locus_tag="KR231_003779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Na/Pi cotransporter family protein"
                     /protein_id="HBH0006100.1"
                     /translation="MNIVISLIGGLGLFLYGMSLMGEGLQKSAGDKLKKIIELLTSNV
                     VMGVLVGTVVTGIIQSSSATTVMVVGFVNAGIMNLSQAIGVIMGANIGTTVTAQLVSF
                     NLEGIAPIALGIGILFYLFTSNQKTKHLSEILIGFGILFTGMEFMKDAVAPLAEYKAF
                     TDALLYFSKNPVLGILAGFAITGIVQSSSASMGMLIALASQGILPLSSALPILYGDNI
                     GTCVTSLLSSVGASRNARRAAVMHLSFNVIGTIIFMLVLNKPISAIVTHFDPTDTARQ
                     IANAHTLFNLTNVIILLPFSKYIVKLANRLIPIKETESEIVNNTKYLDERMFSTPSIA
                     LGNTVQEVVRMGHKATNSLEHSIAGFLNKSNEDINKAFESEKVVNKLQKDILNYLLKL
                     SKEPLRDDEHFRTDLLFNTVNDIERVSDHAENIAELAMSVKEMNISFSDSAIREIYEI
                     YNKTITNFKDALIVLDVKDFELANKVLEVENEVNYLEKTFRNSHMIRLNNGSCTIDAG
                     VLYLDLLTNLERISDHSTNIVKQVLKLKQKI"
BASE COUNT          865 a          277 c          336 g          858 t
ORIGIN      
        1 taactaaaaa atatcattct aaaaggatgt tattttttta catatttttt acaattatag
       61 ttaattcttt gttaaattgt ttgtacataa aatactaaaa atctaagttc aagtatttaa
      121 attgctatat atcataaatt ttctaaaatt aacaacaact taaaaattta acattctctt
      181 aacgtatact taacaaaaca ttaatatttt tattgacaaa atttgttatt ctatattatg
      241 gaaacaataa attttagtta ataaagttta taattcagat aaaaaaatta ttaatttctt
      301 aagggaggaa atatcgtgaa tatagtaatt agccttatcg gtggacttgg actttttctt
      361 tacggaatga gtttaatggg agaaggttta caaaaatcag caggagacaa attaaaaaaa
      421 attattgaac tcttaacaag taatgttgtt atgggtgtac tggtaggtac agtcgttaca
      481 ggtattatac aaagttcaag tgctactact gttatggttg taggatttgt aaatgcaggt
      541 ataatgaatc taagtcaagc tattggtgta ataatggggg caaatatagg tactacagtt
      601 actgctcaat tagtttcatt taatcttgaa ggaattgcac caattgcttt aggtataggt
      661 attttattct atttatttac atcaaatcaa aaaacaaagc atttatctga gatacttata
      721 ggttttggta tattatttac aggaatggag tttatgaaag atgcagtagc tccacttgct
      781 gaatacaaag cattcactga tgcactttta tattttagta aaaatcctgt attaggtata
      841 ttggcaggat ttgccataac tggtattgtt caaagttcaa gtgcatctat gggtatgtta
      901 atagcactag cttctcaagg aatacttcct ctatcatctg ctttacctat tctttatgga
      961 gataatatag gtacttgtgt tacttcactt ttatcaagtg ttggtgcaag tagaaatgct
     1021 cgacgtgcag ctgtaatgca tttaagtttt aatgtaattg gtacaataat atttatgctt
     1081 gttttaaata aacctatatc agccatagtt actcattttg acccaactga tacagctaga
     1141 caaatagcaa atgcacatac tttatttaat cttacaaatg ttataatatt attaccattt
     1201 tctaaataca tagttaaatt agcaaataga cttataccta ttaaagaaac tgaatcagaa
     1261 atagtaaata atactaagta cttagatgaa aggatgttta gcactccatc tatagcactt
     1321 ggtaatactg tacaagaagt tgtaagaatg ggtcataaag ctacaaactc tttggaacat
     1381 tcaattgcag gatttttaaa taagagcaat gaagatatta ataaagcttt tgagtcagaa
     1441 aaagttgtca ataagttaca gaaagatata ttgaactatt tgttaaaact ttctaaagaa
     1501 cctcttagag atgatgaaca ctttagaaca gatttgcttt ttaatactgt aaatgacatt
     1561 gaaagagtct ctgaccatgc agaaaatata gctgaattgg ccatgagtgt taaggaaatg
     1621 aacattagtt tttctgatag tgcgataaga gaaatatacg aaatatacaa taagacaatt
     1681 actaatttta aggatgcctt aatagtttta gatgttaaag attttgagtt agcaaataaa
     1741 gttttagaag ttgaaaatga agtaaattat ttagaaaaaa cttttagaaa ttcacatatg
     1801 attagactaa ataatggaag ttgtacaatt gatgctggtg tactttatct tgacttactt
     1861 actaatctag aaagaatttc tgaccactca acaaatatag taaaacaagt actaaaactt
     1921 aaacaaaaaa tatagtgatt atttttatat ataatcttaa tcaatgagaa gtaagaagct
     1981 atagataatg cttatatcat ttatggtttc ttatttttta tgtaatactc aaatttttat
     2041 agtattctct tattattaaa caatttctgc ctagaatatt ccatatatat atgacttctt
     2101 tcataaaact tgaactgccc ataactaaag tcacaagtat acataactat tttttaatca
     2161 attataacca atatttgttt tatttatctt cattttaatt cttcattcaa taatgtaata
     2221 agattatttt ttatttggat actattatat catctaaata tgttattata tatttggata
     2281 ttttcatatt aataggaggg attctacaat gataaattat atggtagaaa ttatat
//
LOCUS       DAEPHU010000174         2311 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 01A10CD0081
            SAMN05941466-rid12468953.denovo.177, whole genome shotgun sequence.
ACCESSION   DAEPHU010000174 DAEPHU010000000
VERSION     DAEPHU010000174.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941466
            Sequence Read Archive: SRR6291087
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 2311)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2311)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068158.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 22:43:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,892
            CDSs (total)                      :: 3,805
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 87
            rRNAs                             :: 8, 1, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 55
            CDSs (without protein)            :: 55
            Pseudo Genes (ambiguous residues) :: 0 of 55
            Pseudo Genes (frameshifted)       :: 21 of 55
            Pseudo Genes (incomplete)         :: 28 of 55
            Pseudo Genes (internal stop)      :: 16 of 55
            Pseudo Genes (multiple problems)  :: 8 of 55
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2311
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941466-rid12468953.denovo.177"
                     /strain="01A10CD0081"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            <1..878
                     /locus_tag="KR231_003780"
     CDS             <1..878
                     /locus_tag="KR231_003780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="glucosaminidase domain-containing protein"
                     /protein_id="HBH0006101.1"
                     /translation="IVIILIISILIGVLVKEYSSREIKKDDINVSKYIKYADLASKNN
                     AQVNWKYVASIVAVLNKNNLKNVKDSQIQEVSDLFVKNFSKNNKINKLSDILDELEFS
                     NRQKRLVDNYIDNLKDYGIKPERLKSDTKYMKFIDEIKTEAIQNYKDYKILPSITIAQ
                     AIIESSWGKSTLAKQYSNLFGIKADAYWKGKSVTLETKEHLDTIIDDKFRIYDDKNES
                     IKDHAKFLATNKRYKNNGVFDAKTYIYQAKALEKAGYSTAKDENGNSIYAARLIELIQ
                     QYNLQLIDSEIQSEM"
     gene            1315..1806
                     /locus_tag="KR231_003781"
     CDS             1315..1806
                     /locus_tag="KR231_003781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861486.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0006102.1"
                     /translation="MYENNKVIYNLERCEKLEKTLYLSQFNTYKNFKLASKKTVINSL
                     ETYVYNMNINNISLVDTIECISLEDEQLTGKKLILVGDIDIDAILDYAGNKRNRNSSK
                     KNTFKLKIPFSTFIQMPRKIENKDKINLKYLIQDITSSILDDNLFISVTAIISYENSS
                     KIE"
     gene            1834..>2311
                     /locus_tag="KR231_003782"
     CDS             1834..>2311
                     /locus_tag="KR231_003782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0006103.1"
                     /translation="MRITKTTFNDVFSSDANESIIKVEKYVDKKCASVFEILTYTIIV
                     TNTNRYKTGNIFFKDYISKYIEFINNTVKVNGIIKRGLDPQQGFYIGRIDASCKKIIS
                     FKSVVLPNSAHRIIKNSANIYYYYKCNLDKFPTRISIESNRVYTNVNKIVFKQLNIS"
BASE COUNT          996 a          213 c          334 g          768 t
ORIGIN      
        1 tcattgttat aatactgata atatcaattt taataggtgt attagtgaag gaatattcat
       61 ctagagagat aaaaaaggat gatataaatg tcagtaagta tataaaatat gctgatttag
      121 caagtaaaaa taatgcacaa gttaactgga agtatgtagc ttccattgtt gctgtgttaa
      181 ataaaaataa cttaaaaaac gttaaggatt cacagataca agaagtatca gatttatttg
      241 ttaagaattt ttctaaaaat aataaaataa ataagttaag tgatattttg gatgagttag
      301 aatttagtaa tagacaaaaa agattggttg ataattatat agacaatctt aaggattatg
      361 gtataaaacc agaaagattg aagtctgata caaaatatat gaagtttatt gatgaaatta
      421 aaacagaagc aatacaaaat tataaggatt ataaaatact tccatctata actattgcac
      481 aagctataat agaatctagc tggggcaagt caactttggc aaaacaatat agcaatctat
      541 ttggtataaa ggctgacgct tattggaaag gtaagtcagt gactttagaa acgaaagaac
      601 atttagatac aattatagat gataaattta gaatatatga tgataaaaat gaatctataa
      661 aagaccatgc aaaattttta gccacaaata aaaggtataa aaacaatggt gtatttgatg
      721 caaaaacgta tatatatcaa gctaaagcat tagaaaaggc aggttatagt actgcgaagg
      781 atgaaaatgg caatagtata tatgcagctc gtctaataga attaattcaa cagtataatc
      841 ttcaattaat agacagtgaa attcaaagtg aaatgtaact ttgattaaat ttttattgat
      901 aaggctatga tttttaaaat catagcctta ttttgacatg cttttacttg taattattaa
      961 atcgatatca ttatctttca aaatttactt tatactgtaa atcaaattat ttaagttaaa
     1021 acttggaatt atttataaaa ggattattta ctttatctaa attctgcact taaagaacat
     1081 cttttccctt aagactgacc gttagtctat aaaaattata attacttata aaaaagtgaa
     1141 tatatatata aagttttcag aaagactttt acttgtaaat tgaaatcaat gaagtaaaaa
     1201 aggattcttt cttaaaagta aataacaact agatagtgaa taataaaaaa tggtaatttg
     1261 aaataatttt tatgaatagt attaatatat agatacaggg agattgatgc gattatgtat
     1321 gaaaataata aggtaatata caaccttgaa agatgtgaaa aactagaaaa gactctttat
     1381 ttatctcaat ttaatacata taaaaatttt aaattagctt ctaaaaaaac tgtaataaat
     1441 tcattagaga catatgttta caatatgaat attaacaata taagtcttgt tgatactata
     1501 gaatgtatat cattagaaga tgaacaactt acaggaaaga agttgatttt agttggtgat
     1561 atagatattg atgcaatatt agattatgca ggaaataaaa gaaatagaaa ttctagtaaa
     1621 aaaaatacat ttaaattaaa aatacccttt agtacattta tacaaatgcc tagaaagata
     1681 gaaaataaag ataaaattaa tttaaagtat cttatacaag atattacttc atctatttta
     1741 gatgataatt tatttattag tgttactgca attataagtt atgaaaatag ttccaagata
     1801 gagtaatctt taaattatag aaaggtggat gcaatgagaa taacgaaaac tacttttaat
     1861 gatgtatttt caagtgatgc aaatgaaagt attataaaag tagaaaaata tgttgataaa
     1921 aaatgtgcat ctgtatttga gattttgacc tacactatta ttgttacaaa tacaaatagg
     1981 tacaaaactg gaaatatatt tttcaaagat tatatttcta aatatataga gtttataaat
     2041 aatactgtaa aagttaatgg cattataaaa cgtggattag acccacagca aggtttttac
     2101 atagggagaa tagatgcaag ttgtaaaaaa ataatatctt ttaagagtgt agttttacca
     2161 aattctgcac ataggattat aaagaatagt gctaatatat actattatta taagtgtaat
     2221 ctagataaat tcccaacaag aatatcaata gaaagtaata gagtttatac taatgtaaat
     2281 aaaattgtat tcaaacaatt gaatataagt a
//
LOCUS       DAEPHU010000175         2195 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 01A10CD0081
            SAMN05941466-rid12468953.denovo.178, whole genome shotgun sequence.
ACCESSION   DAEPHU010000175 DAEPHU010000000
VERSION     DAEPHU010000175.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941466
            Sequence Read Archive: SRR6291087
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 2195)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2195)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068158.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 22:43:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,892
            CDSs (total)                      :: 3,805
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 87
            rRNAs                             :: 8, 1, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 55
            CDSs (without protein)            :: 55
            Pseudo Genes (ambiguous residues) :: 0 of 55
            Pseudo Genes (frameshifted)       :: 21 of 55
            Pseudo Genes (incomplete)         :: 28 of 55
            Pseudo Genes (internal stop)      :: 16 of 55
            Pseudo Genes (multiple problems)  :: 8 of 55
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2195
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941466-rid12468953.denovo.178"
                     /strain="01A10CD0081"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            240..986
                     /locus_tag="KR231_003783"
     CDS             240..986
                     /locus_tag="KR231_003783"
                     /EC_number="2.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolipoprotein diacylglyceryl transferase"
                     /protein_id="HBH0006104.1"
                     /translation="MDRVAFTLFGIDIMWYGILMACGMILGTLIAIKEAKRVGIKEDD
                     VLNIAIIAIPVGLICARIYYVVFNWSYYAQNMSQIFNFRGGGLAIHGGLIGGILAGYI
                     YTKIKNINFLKMADTVILGMPLAQAIGRWGNFINGEAHGGATNLPWGIMVDGVKVHPT
                     FLYESIWDFGIFIVLLLFRKNKKYEGQVIVTYITLYSIGRFFIEGLRTDSLMLGPLRM
                     AQVISLIGVIGGIIAHVYLSKKNKNNISEE"
     gene            1016..1951
                     /gene="rsmH"
                     /locus_tag="KR231_003784"
     CDS             1016..1951
                     /gene="rsmH"
                     /locus_tag="KR231_003784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427011.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(1402)-N(4))-methyltransferase
                     RsmH"
                     /protein_id="HBH0006105.1"
                     /translation="MEFHHVSVLLNECIENLNIKPDGVYVDCTMGGAGHSKEIVKKLS
                     DKGLFIGFDQDKNAISTAKERLSEYESRVKFVHSNFENIKEELEKIGVYKIDGVLADL
                     GVSSHQLDEADRGFSYMQDAPLDMRMDVRCEFSAYDVVNTYTEDELTKIIKDYGEDNW
                     AKRIAKFIVEERANKPIETTGELVDVIKKAIPKKARIDGPHPAKRTFQAIRIEVNNEL
                     GVITKMINDASSIMNEGGRICIITFHSLEDRIVKNAFKHLASDCICPQHLPICQCDKE
                     SEVKIITRKPILPSEEEIEVNPRSRSAKLRVAEKI"
BASE COUNT          870 a          200 c          418 g          707 t
ORIGIN      
        1 atcaatcttt ttgattaaaa aatatctatg tacacttgta actttagtca tgagagattc
       61 agtttaaaaa attttatagt aattagatat aatatagtgt agggagttgt agaataaatt
      121 ttaatatttt ttgtagaatt aacattaatg tgttatcata atttagtata attacaatta
      181 attgtaatta tagcatattg ctttggaaat attttcaatt aatacaaaga ggtgacgtta
      241 tggatagagt agcatttaca ctgtttggca tagacatcat gtggtatgga atacttatgg
      301 catgtggaat gattttagga actttaatag caataaaaga agcaaaaaga gtgggaatta
      361 aagaagatga tgtattaaat atagctataa tagcaattcc agttggacta atctgtgcaa
      421 gaatctatta tgttgtattt aattggagtt actatgctca aaatatgtct caaattttta
      481 attttagagg tggtggactt gctatacatg gagggttaat tggtggaata ttagctggtt
      541 atatatacac taagattaaa aatattaact tcttaaaaat ggctgataca gttatacttg
      601 gaatgccttt agcacaagct attggaagat ggggaaattt tattaatgga gaagcacatg
      661 gaggtgctac caatttacct tggggaataa tggttgatgg agtaaaggta catccaactt
      721 ttttatatga gtctatatgg gattttggaa tatttatagt tttattacta tttagaaaaa
      781 ataaaaaata tgaaggtcaa gttatagtta cttatataac tttatattca ataggaagat
      841 tttttataga gggattaaga acagatagtt taatgttagg accacttaga atggcacaag
      901 ttataagtct aattggagtt attggtggca taattgcaca tgtttattta tcaaagaaaa
      961 ataaaaataa tattagtgaa gaatagttta aaaagtgaat ttaagggagg taactatgga
     1021 atttcatcat gtatcagttc ttttaaatga gtgtatagag aatttaaata taaagccaga
     1081 tggcgtgtat gttgactgta ctatgggagg agcaggacat tctaaagaaa tagtaaaaaa
     1141 actgtcagat aagggattat ttatagggtt tgaccaagat aaaaatgcta taagcacagc
     1201 aaaagagaga ttgagtgaat atgaaagtag agtgaagttt gttcacagca attttgaaaa
     1261 tataaaagag gaattagaaa aaataggagt ttacaaaatt gatggtgtat tagctgattt
     1321 aggagtttca tctcaccaac ttgatgaagc tgatagagga ttttcttata tgcaagatgc
     1381 accacttgat atgagaatgg atgttaggtg tgagttttct gcatatgatg ttgtaaatac
     1441 ttatacagaa gatgaattaa ctaagataat aaaagattat ggagaagata actgggctaa
     1501 gcgtatagct aaatttatag ttgaagaaag agcaaacaaa ccaatagaaa ctacaggaga
     1561 attagtagat gtaattaaaa aagctatccc taagaaagct agaatagatg gacctcaccc
     1621 agctaaaaga acttttcagg caatacgaat agaagtaaat aatgaacttg gagtaattac
     1681 aaagatgata aatgatgctt cttctataat gaatgaaggt ggaagaatat gtataataac
     1741 attccattca ttagaagata gaatagtgaa aaatgcattt aagcatttag catcagattg
     1801 tatatgtcca caacatttac ctatatgcca atgtgataaa gaatctgagg tgaaaataat
     1861 aactagaaaa cctatattac ctagtgagga agaaatagaa gtaaatccac gttcaagaag
     1921 tgctaagcta agagtagcag aaaaaatata agtagttata aggctaaaga ataatcttat
     1981 atataaaata agattattat aattaattaa aaagtattat atattttgtt gcactggtaa
     2041 agcaattaaa aaacaattaa cactataaga aatgttcttt gttattgaga tatataatga
     2101 aaatttagat ataaaaatat agatatagat ggtattaagt aatataatgg agaacttagg
     2161 aatcagagag tagatagtta gttacatatt atatt
//
LOCUS       DAEPHU010000176         2162 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 01A10CD0081
            SAMN05941466-rid12468953.denovo.179, whole genome shotgun sequence.
ACCESSION   DAEPHU010000176 DAEPHU010000000
VERSION     DAEPHU010000176.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941466
            Sequence Read Archive: SRR6291087
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 2162)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2162)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068158.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 22:43:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,892
            CDSs (total)                      :: 3,805
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 87
            rRNAs                             :: 8, 1, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 55
            CDSs (without protein)            :: 55
            Pseudo Genes (ambiguous residues) :: 0 of 55
            Pseudo Genes (frameshifted)       :: 21 of 55
            Pseudo Genes (incomplete)         :: 28 of 55
            Pseudo Genes (internal stop)      :: 16 of 55
            Pseudo Genes (multiple problems)  :: 8 of 55
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2162
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941466-rid12468953.denovo.179"
                     /strain="01A10CD0081"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            <1..128
                     /locus_tag="KR231_003785"
     rRNA            <1..128
                     /locus_tag="KR231_003785"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
     gene            260..376
                     /gene="rrf"
                     /locus_tag="KR231_003786"
     rRNA            260..376
                     /gene="rrf"
                     /locus_tag="KR231_003786"
                     /product="5S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00001"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00001"
     gene            383..457
                     /locus_tag="KR231_003787"
     tRNA            383..457
                     /locus_tag="KR231_003787"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:415..417,aa:Asn,seq:gtt)
     gene            462..536
                     /locus_tag="KR231_003788"
     tRNA            462..536
                     /locus_tag="KR231_003788"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:495..497,aa:Glu,seq:ttc)
     gene            542..617
                     /locus_tag="KR231_003789"
     tRNA            542..617
                     /locus_tag="KR231_003789"
                     /product="tRNA-Val"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:575..577,aa:Val,seq:tac)
     gene            623..699
                     /locus_tag="KR231_003790"
     tRNA            623..699
                     /locus_tag="KR231_003790"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:657..659,aa:Asp,seq:gtc)
     gene            710..784
                     /locus_tag="KR231_003791"
     tRNA            710..784
                     /locus_tag="KR231_003791"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:742..744,aa:Thr,seq:tgt)
     gene            799..883
                     /locus_tag="KR231_003792"
     tRNA            799..883
                     /locus_tag="KR231_003792"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:833..835,aa:Tyr,seq:gta)
     gene            893..966
                     /locus_tag="KR231_003793"
     tRNA            893..966
                     /locus_tag="KR231_003793"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:925..927,aa:Gly,seq:tcc)
     gene            977..1053
                     /locus_tag="KR231_003794"
     tRNA            977..1053
                     /locus_tag="KR231_003794"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1011..1013,aa:Arg,seq:tct)
     gene            1063..1138
                     /locus_tag="KR231_003795"
     tRNA            1063..1138
                     /locus_tag="KR231_003795"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1096..1098,aa:Gln,seq:ttg)
     gene            1150..1225
                     /locus_tag="KR231_003796"
     tRNA            1150..1225
                     /locus_tag="KR231_003796"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1183..1185,aa:Lys,seq:ttt)
     gene            1228..1316
                     /locus_tag="KR231_003797"
     tRNA            1228..1316
                     /locus_tag="KR231_003797"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1262..1264,aa:Ser,seq:tga)
     gene            1334..1424
                     /locus_tag="KR231_003798"
     tRNA            1334..1424
                     /locus_tag="KR231_003798"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1368..1370,aa:Ser,seq:gct)
     gene            1433..1509
                     /locus_tag="KR231_003799"
     tRNA            1433..1509
                     /locus_tag="KR231_003799"
                     /product="tRNA-Pro"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1467..1469,aa:Pro,seq:tgg)
     gene            1595..1670
                     /locus_tag="KR231_003800"
     tRNA            1595..1670
                     /locus_tag="KR231_003800"
                     /product="tRNA-Trp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1628..1630,aa:Trp,seq:cca)
     gene            1731..1807
                     /locus_tag="KR231_003801"
     tRNA            1731..1807
                     /locus_tag="KR231_003801"
                     /product="tRNA-Pro"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1765..1767,aa:Pro,seq:tgg)
     gene            1814..1890
                     /locus_tag="KR231_003802"
     tRNA            1814..1890
                     /locus_tag="KR231_003802"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1848..1850,aa:Ile,seq:gat)
     gene            1894..1969
                     /locus_tag="KR231_003803"
     tRNA            1894..1969
                     /locus_tag="KR231_003803"
                     /product="tRNA-Phe"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1927..1929,aa:Phe,seq:gaa)
     gene            1977..2053
                     /locus_tag="KR231_003804"
     tRNA            1977..2053
                     /locus_tag="KR231_003804"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:2011..2013,aa:Met,seq:cat)
BASE COUNT          572 a          480 c          570 g          540 t
ORIGIN      
        1 caacttcaag ataagatttc ccaccgcaag ggtaagaccc cagaaagact atctggttga
       61 taggtcgaag gtgtaagtgc agcaatgtat ttagcttatc gatactaata ggtcgaggac
      121 ttgaccaata ttatttgatg tcattcatta agatatatgt gcagttttta gagtgttaac
      181 tctaaaaaaa aataaaaaaa gtattgacaa aaatagtaaa aaatgttaat attatacttg
      241 tcctagcaac aagaaaaaat gtggttataa tagcggagga gatacacctg tttccattcc
      301 gaacacagaa gttaagttct ctagcgctga tggtacttgg tgggaaactg cctgggagag
      361 taggacatag ccacgtgaat gttccaaggt agctcaacgg tggagcaacc ggctgttaac
      421 cggtaggctg tgggttcgag ccccaccctt ggagccatta tggctcgttg gtcaagaggt
      481 taagacaccg ccctttcacg gcggtaacag gggttcaatt cccctacgag tcaccatttg
      541 tgggatcata gctcagctgg gagagcacct gccttacaag cagggggtca caggttcgag
      601 ccctgttggt cccaccattt gcggcctggt agttcagttg gttagaatgc cagcctgtca
      661 cgctggaggt cgagggttcg agccccttcc aggtcgccaa aataaaaatg ctggtgtggc
      721 tcaacggtag agcagctgac ttgtaatcag caggttgtag gttcgattcc tatcaccagc
      781 tccatgtaaa actaatacgg aggatttccc gagcggccaa agggggcaga ctgtaaatct
      841 gttgtcatcg acttcggtgg ttcgaatcca ccatcctcca ccaattaaat atgcgggtgt
      901 agctcaatgg tagagttctg gccttccaag ccagctgtga gggttcgatc cccttcaccc
      961 gctccaaaga aagcgtgggt gcatagctca gctggataga gcaacgccct tctaaggcgt
     1021 gtgtccgggg ttcgaatccc tgtgcgctca ccacatatat attggggatt agccaagtcg
     1081 gtaaggcaca tgactttgac tcatgtatgc gtaggttcga gtcctgcatc cccagccaaa
     1141 taaaaatatg gtctattagc tcagtcggta gagcacctga cttttaatca gggtgtcccg
     1201 cgttcgagtc gcggatagat caccaatgga gaggtgtccg agtggtttaa ggagctggtc
     1261 ttgaaaacca gtgacttcga aaggggccgt gggttcgaat cccaccctct ccgccaaaaa
     1321 aatgactgaa tttggagaag tactcaagtg gctcaagagg atcccctgct aagggattag
     1381 gctgggtaac cggtgcgagg gttcgaatcc ctccttctcc gccattcaaa aacgaggtgt
     1441 agcgcagttt ggtagcgcac atggtttggg accatggggc cgggggttcg agtcccttca
     1501 cctcgaccaa cttaagcttt tagttcagtt ggttagagtg cccaactcat ggctagtaat
     1561 tctagggttt gagtccatga aggttattct tcataggggt gtagctcagt tggtagagcg
     1621 tcggtctcca aaaccgtgcg ccgggggttc gagtccctcc acccctgcca aataaaaagg
     1681 acttgaaaaa agttggattt tagagtagta taagatagta aataagattt cgaggtgtag
     1741 cgcagtttgg tagcgcacat ggtttgggac catggggccg ggggttcgag tcccttcacc
     1801 tcgaccaaga aaagggccta tagctcaggt ggttagagcg cacgcctgat aagcgtgagg
     1861 tcgctggttc gagtccagct aggcccacca tttgcccaga tagctcagtc ggtagagcag
     1921 gggactgaaa atccccgtgt cggtggttcg attccgcctc tgggcaccag gaatacggcg
     1981 gtatagctta gttggctaga gcgttcggtt catacccgaa aggtcatagg ttcgactcct
     2041 attaccgcta ccatctaact atatcaataa agaactttga aaattaaaca gtaggttaat
     2101 ttataaacaa gaaacaaacc ataaagccag atattttgat aacaatagta tctgagcctg
     2161 at
//
LOCUS       DAEPHU010000177         2054 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 01A10CD0081
            SAMN05941466-rid12468953.denovo.180, whole genome shotgun sequence.
ACCESSION   DAEPHU010000177 DAEPHU010000000
VERSION     DAEPHU010000177.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941466
            Sequence Read Archive: SRR6291087
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 2054)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2054)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068158.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 22:43:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,892
            CDSs (total)                      :: 3,805
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 87
            rRNAs                             :: 8, 1, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 55
            CDSs (without protein)            :: 55
            Pseudo Genes (ambiguous residues) :: 0 of 55
            Pseudo Genes (frameshifted)       :: 21 of 55
            Pseudo Genes (incomplete)         :: 28 of 55
            Pseudo Genes (internal stop)      :: 16 of 55
            Pseudo Genes (multiple problems)  :: 8 of 55
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2054
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941466-rid12468953.denovo.180"
                     /strain="01A10CD0081"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            complement(10..561)
                     /locus_tag="KR231_003805"
     CDS             complement(10..561)
                     /locus_tag="KR231_003805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBH0006106.1"
                     /translation="MSINTVIAKNLNRLRNERNLSLGQLAELSGVSKVMLSQIEKGDS
                     NPTVNTIWKIASGLNVPYTAILEQPQNETFIVSKTDIDVQVSENKDYRLYCYYPNTPT
                     RNFELFQMELEEGHSYTSVGHSEKSQEYIMIIEGQLKLEVNDSIYQLRENDSICFSAE
                     SIHTYHNQGEKTLKAVIINYYPV"
     gene            752..1714
                     /locus_tag="KR231_003806"
     CDS             752..1714
                     /locus_tag="KR231_003806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine synthase family protein"
                     /protein_id="HBH0006107.1"
                     /translation="MRVLNNVTEAIGNTHMLHLSKIADEFGVQGNIYAKMEYLNPGFS
                     KKDRVALQMITEAENAGLLVPGQAVVELTSGNTGTGLAIACACKGYKFIACMSKGNSM
                     ERARMMKALGAEVVLVDQMPNSVHGQVSGEDLALVEIEAQKIAKERNAFRADQFNLEA
                     CNHAHEKYTAEEMWEQLDGNIDVFVDFLGSGSTFAGCSKTLKKHNSSIKCYVVEPETA
                     AIYSGKEITDQGHKIQGGGYSMDLPLVDKKLIDGYIQVTDEEATDVARKLAKLEGVFA
                     GFSSGANVCAAIKLLKSSEKGKNIVLTLNDSGLKYLSTDLYEEL"
BASE COUNT          759 a          230 c          365 g          700 t
ORIGIN      
        1 atggcatggc taaactggat aataatttat tattactgct ttcaatgttt tttctccttg
       61 attatggtat gtatgaattg attcagctga aaaacaaata gagtcatttt ctctaagttg
      121 ataaatagag tcatttactt ctaattttaa ttgaccttct ataatcataa tatattcctg
      181 tgatttttca gaatgaccaa cagatgtata actatgacct tcttctaatt ccatttgaaa
      241 taattcgaag tttctagttg gtgtattggg ataataacaa taaagacgat aatctttatt
      301 ttctgaaact tgtacatcta tatcagtttt tgatacaata aaagtttcat tttgaggttg
      361 ttccagtatt gcagtatatg gaacatttag tccacttgca attttccaaa ttgtgtttac
      421 tgttgggttt gagtctccct tttcaatttg agaaagcatt actttactta cgccagataa
      481 ttcagcaagt tgacctagac ttaagttacg ttcattacgt aatctattta aatttttagc
      541 aataacagta ttaatactca tagtagctcc ttaaaatgta aattattgac aaatataatt
      601 tacgaatgta taatttattt aacattattt ataatttaca aatgtataat ataatgaacg
      661 ttaaatacac tgtacatccg taatataaat tatactgcat aaagagttgt ttttcaacgg
      721 atgatagttg agagattaag ggggaattgt aatgcgtgta cttaataatg ttacagaggc
      781 tataggcaat actcatatgt tacatttatc caaaatagca gatgaatttg gagttcaagg
      841 taatatttat gcaaagatgg aatacttaaa tccgggattt agtaaaaagg accgtgtagc
      901 attacaaatg attaccgaag cagaaaatgc aggtttatta gttccaggtc aagcagttgt
      961 ggaattaaca agtggtaata ctggaacagg actagcaata gcttgtgcat gtaaaggata
     1021 taaatttata gcgtgtatgt caaaaggaaa ttctatggaa agagcaagaa tgatgaaagc
     1081 tttaggtgct gaagtagttc ttgtagacca aatgcctaat tcagttcatg gacaggtatc
     1141 tggtgaagat ttggcacttg tagaaattga ggctcaaaaa atagcaaaag aaagaaatgc
     1201 atttagagca gaccaattta atttagaagc ttgtaatcat gcacatgaaa agtatacagc
     1261 agaagaaatg tgggaacaat tggatggaaa tattgatgta tttgtagatt ttcttggaag
     1321 tggtagtact tttgcaggat gttcaaaaac acttaaaaaa cataattctt ctatcaaatg
     1381 ttatgttgtt gaacctgaaa cagcagcaat ttattcaggt aaagaaataa ctgaccaagg
     1441 gcataaaata caaggtggag gatattctat ggatttgcca ttagtagaca agaaacttat
     1501 tgatggttat attcaagtta cagacgagga ggcaactgat gtagcaagaa aattagctaa
     1561 attagaaggt gtatttgcag gattttcttc aggggcaaat gtatgtgcag caattaagtt
     1621 gttaaagagc agtgaaaaag gaaaaaatat agttttaact cttaatgata gtggtttaaa
     1681 atatttaagt actgatttat atgaagaatt gtaataatag cacaatagtt atgcaatgtt
     1741 ttttaaatta agtatataga tttaaattat aaaaagtatc tcaatgtaaa ttttgaaagt
     1801 tataaaggag atactttttt attttgtaaa tatggagtat cctacttata agtattaagc
     1861 tatatagata ttgatgatta gctatgcaat aaaaaagagt atgtgttttt gcatttatac
     1921 atcataactt ggaataatac atattaatgt tctaaatgta tttaaaatat atgataaaat
     1981 tagaacaaat agatacaagg agataaaaat gcaaaagaga attttaagaa attttatatt
     2041 tacgggtaaa aata
//
LOCUS       DAEPHU010000178         1919 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 01A10CD0081
            SAMN05941466-rid12468953.denovo.181, whole genome shotgun sequence.
ACCESSION   DAEPHU010000178 DAEPHU010000000
VERSION     DAEPHU010000178.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941466
            Sequence Read Archive: SRR6291087
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1919)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1919)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068158.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 22:43:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,892
            CDSs (total)                      :: 3,805
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 87
            rRNAs                             :: 8, 1, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 55
            CDSs (without protein)            :: 55
            Pseudo Genes (ambiguous residues) :: 0 of 55
            Pseudo Genes (frameshifted)       :: 21 of 55
            Pseudo Genes (incomplete)         :: 28 of 55
            Pseudo Genes (internal stop)      :: 16 of 55
            Pseudo Genes (multiple problems)  :: 8 of 55
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1919
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941466-rid12468953.denovo.181"
                     /strain="01A10CD0081"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            30..404
                     /locus_tag="KR231_003807"
     CDS             30..404
                     /locus_tag="KR231_003807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBH0006108.1"
                     /translation="MNIVISNSSGKPIYEQITTQIKSMIISGELPEGSALPSMRLLAK
                     ELRISVITTKRAYSDLERDGFIETVTGKGSFVSSKNMDFVKEEQFRLIEEYLQKAVDT
                     AKSSDITYDELKDILFLLYKGE"
     gene            401..1264
                     /locus_tag="KR231_003808"
     CDS             401..1264
                     /locus_tag="KR231_003808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH0006109.1"
                     /translation="MISMDAITIKNLNKTYKDFSLQDISFSVPKGSVMGFVGENGAGK
                     TTTLKAILNLISYDSGNIEIFGLDSKKNEKEIKEQIGVVFEGSNFHENLNTDHVSKIM
                     SKIYKNWNDTLFKDYLKKLRVPDNKLIKEFSKGNKMKLSIAVALSHKPKLLILDEATS
                     SLDPIVREEILDIFLDFIQDEEHSIILSSHITSDLDKIADYITFIHKGKIVFSENKDE
                     LIDTMGVLKCKPSDFDNLSREDYSYYRKSQFGYEVLLKDKHRFISRHPNCIVDNTSIE
                     EIMLFYVRGDK"
     gene            1264..1902
                     /locus_tag="KR231_003809"
     CDS             1264..1902
                     /locus_tag="KR231_003809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-2 transporter permease"
                     /protein_id="HBH0006110.1"
                     /translation="MKGLILKDLLNLKGNIKFILLFIIMFGFMSSLGDGNVNNFIGVI
                     IVLCTTMIVSTFSYDDLNKWDSYVLTMPINRNDIVLSKYLTMLIFSFIGVLVSLIVSV
                     TIGYFKNTLILNETLLINALILSISVCFGSLILPLIYKFGTERARLLMILCFLVPTLA
                     LLVFKSILENISSPISIEIILNTLVYSLPFVAILLFVISYFISSKIYSKKEV"
BASE COUNT          734 a          203 c          297 g          685 t
ORIGIN      
        1 ctatatatac aatttaagga ggtgtcttat tgaatatagt tattagtaat tcgagtggga
       61 agccaatata tgaacagatt actacacaaa ttaaaagtat gattataagt ggagagttac
      121 cagaaggctc agctcttcca agtatgagac tattggcaaa agaacttaga ataagtgtaa
      181 ttactacaaa acgagcatat agcgatttag aacgagacgg atttattgag acagttactg
      241 gtaaaggcag ttttgtatct agtaaaaaca tggattttgt caaagaagaa caatttcgtt
      301 taattgaaga atacctacaa aaagcagttg atacagcaaa aagtagtgat attacatatg
      361 acgaattaaa agatatttta tttttattat ataaaggaga atgataagta tggatgcaat
      421 aactataaaa aatttaaata aaacttataa agattttagc ctacaagata tatctttttc
      481 agtaccaaaa gggagtgtaa tgggatttgt aggtgaaaat ggtgcaggaa aaacaactac
      541 attaaaagca attttaaatt taatatctta tgatagtgga aatatagaaa tctttggtct
      601 tgatagtaaa aaaaatgaaa aagaaattaa agagcaaatt ggggttgtat ttgagggaag
      661 caactttcat gaaaatttaa acactgacca tgtttcaaaa atcatgagta aaatctataa
      721 aaattggaat gacacattat ttaaagacta cttaaaaaaa ttgagagtac cagacaataa
      781 attaattaag gagttttcaa aggggaataa gatgaaactt agtattgctg tagccttatc
      841 tcataaacca aaattattaa tactagatga ggcaactagt tcacttgacc ctatcgttcg
      901 tgaagaaata ctagatatat ttttagattt tatacaagat gaagaacact ctattatctt
      961 atcttcacat attacaagtg atttagataa gatagcagac tatattacat ttatacataa
     1021 aggaaaaatt gtatttagtg aaaataagga tgaattaatt gatactatgg gagttttaaa
     1081 atgtaaacct agtgattttg ataacctttc aagagaggat tattcatatt atcgtaaaag
     1141 ccaatttgga tatgaagtac ttcttaaaga taagcataga tttatctcaa gacatccaaa
     1201 ctgtattgtt gataatacgt ctatagaaga aattatgtta ttttatgtga gaggtgataa
     1261 ataatgaaag gtctaatttt aaaagattta cttaatttga aaggaaatat aaagtttata
     1321 cttttattca tcattatgtt tggctttatg tcttctttag gagatggaaa tgttaataac
     1381 tttataggtg ttattatagt tttatgtact acaatgattg tttcaacatt ttcatatgat
     1441 gatttgaata aatgggatag ttatgtactt acaatgccta ttaatcgcaa tgatattgta
     1501 ttaagtaaat atttaactat gttaatattt agctttatag gtgttcttgt ttcacttatt
     1561 gttagtgtaa ctattggtta ttttaaaaat acacttatat taaatgaaac actacttatt
     1621 aatgcactaa tcttatcaat ttcagtatgt tttggtagcc ttattctacc acttatttat
     1681 aaatttggta cagaaagagc tcgtttatta atgattttat gctttttagt tccaacacta
     1741 gctttattag tttttaaaag tattttagaa aatattagtt cacctatttc tatagaaatt
     1801 atacttaata cactagtata ttctcttcca tttgttgcta ttttactatt tgtgatttca
     1861 tattttatat catcaaaaat ctatagtaaa aaagaagtat aaaatatact atatatgtt
//
LOCUS       DAEPHU010000179         1805 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 01A10CD0081
            SAMN05941466-rid12468953.denovo.183, whole genome shotgun sequence.
ACCESSION   DAEPHU010000179 DAEPHU010000000
VERSION     DAEPHU010000179.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941466
            Sequence Read Archive: SRR6291087
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1805)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1805)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068158.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 22:43:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,892
            CDSs (total)                      :: 3,805
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 87
            rRNAs                             :: 8, 1, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 55
            CDSs (without protein)            :: 55
            Pseudo Genes (ambiguous residues) :: 0 of 55
            Pseudo Genes (frameshifted)       :: 21 of 55
            Pseudo Genes (incomplete)         :: 28 of 55
            Pseudo Genes (internal stop)      :: 16 of 55
            Pseudo Genes (multiple problems)  :: 8 of 55
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1805
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941466-rid12468953.denovo.183"
                     /strain="01A10CD0081"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            complement(<1..92)
                     /locus_tag="KR231_003810"
     CDS             complement(<1..92)
                     /locus_tag="KR231_003810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011058338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0006111.1"
                     /translation="MKDKWILCPVCGNKTRLKIRADTELKNFPL"
     gene            complement(131..418)
                     /locus_tag="KR231_003811"
     CDS             complement(131..418)
                     /locus_tag="KR231_003811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015574378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0006112.1"
                     /translation="MSTLIIGFIVAGVLLIAEYLLCTKFRSPLWGGIIPLLILAGTIY
                     VFASGRIPFERPYIFPFVVVNTLFFGDWGTGRDKYKKIKQTEMEKMKAKDI"
     gene            complement(421..717)
                     /locus_tag="KR231_003812"
     CDS             complement(421..717)
                     /locus_tag="KR231_003812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009460866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2089 family protein"
                     /protein_id="HBH0006113.1"
                     /translation="MELDKIPQWILALEQEDATFLKNFALKSGSLKEIAKMYGVSYPT
                     VRLRLDKLIQKIEMCDQQEEEPFQTFIKGLAVDSRIDVETAKIIIEKYKKEKEK"
     gene            complement(806..1711)
                     /locus_tag="KR231_003813"
     CDS             complement(806..1711)
                     /locus_tag="KR231_003813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HBH0006114.1"
                     /translation="MFKKNKKQTENVKEKKVRTVKVGTHKKSVIALWVVLIASVSFGV
                     YKNFTAIDMHTVHETETIQLRLTDTNGIENFVKNFAKSYYTWNNSKEAIEARTQAISG
                     YLTKELQALNTDTIRKDIPVSSAVNGVQIWSVTQADENQFSVIFTVEQLITENGSTKT
                     VRSAYEVTVYVDGSGNMVLTKNPTITSIPVKSGYTPKAKESDGTVDAVTTDEINEFLT
                     TFFKLYPTATAKELSYYVNEGVLKPIGKDYVFSELVNPIYNRIDSQVTVSVAVKYLDQ
                     QTKATQVSQFDLVLEKSGSNWKIIK"
BASE COUNT          485 a          397 c          300 g          623 t
ORIGIN      
        1 aatagtggga aatttttaag ctctgtgtcc gctctaattt tcaacctcgt tttattaccg
       61 caaactggac ataaaatcca tttatctttc aataatgcgt tcctcctatc taagtataca
      121 gttttgtaat ttatatatct ttagctttca tcttttccat ttcagtttgc tttatctttt
      181 tatatttatc cctgccagta ccccaatctc caaaaaataa agtattgact acaacaaacg
      241 ggaaaatata tggtctttca aatggtattc tgccacttgc aaaaacatat attgttcctg
      301 ccaagataag caagggaata atacctcccc aaagaggact tctaaatttt gtgcagagaa
      361 gatactctgc aattaataaa actcctgcaa caataaagcc aataattaat gtactcatgg
      421 ttatttctcc ttttcttttt tatatttttc aataattatc tttgcagttt ccacgtcaat
      481 tcgagaatca accgctaacc ctttaataaa agtttggaaa ggttcttctt cctgctggtc
      541 gcacatttca attttttgaa ttaatttgtc taaacgtaat cgaacagtag ggtaagatac
      601 cccatacatt ttcgctattt cctttaatga accggattta agtgcgaagt ttttaagaaa
      661 agtagcgtcc tcttgctcta aggcaagaat ccattgaggg attttatcaa gctccaaaaa
      721 cacaactcct ttcatattat ctttaacaat attcagtata tcataaataa aattaaagtc
      781 aataagaatt taaacatcaa aataattatt ttataatctt ccagttgctc ccgctttttt
      841 ccagcaccaa atcaaattgt gatacctgcg ttgcctttgt ctgctggtcg aggtacttca
      901 cagccacgga aaccgtcact tgactgtcga tgcggttgta gatgggattt accagttccg
      961 agaatacata atctttcccg ataggcttta acacgccctc atttacataa taggacagct
     1021 ctttagcggt tgcggttggg tagagcttaa agaacgtcgt cagaaattcg ttgatttcgt
     1081 ccgtcgtcac agcgtccacc gttccgtcgc tttcctttgc ctttggcgtg tagccggatt
     1141 tcacgggtat gctggtaatg gtcggattct tcgtgagaac catgtttcca gagccatcca
     1201 catagaccgt gacttcatag gcggagcgta ccgtcttcgt gcttccattc tccgtgatta
     1261 actgttccac agtgaagatc acggagaact ggttttcatc cgcctgcgtg acagaccata
     1321 tctgtacccc attgaccgcc gaagacactg gaatatcctt gcggatggta tcggtattaa
     1381 gtgcctgcaa ttcctttgtc agataaccgc tgattgcctg cgtccttgct tcaatagctt
     1441 ctttgctgtt attccatgtg taataggact tcgcaaagtt cttcacgaaa ttttcaatcc
     1501 cgttggtatc ggtaagtctt aactgtatgg tttctgtttc atgtacggtg tgcatatcaa
     1561 tagcggtaaa attcttatat accccaaaac tcacgcttgc gataagcact acccacaatg
     1621 caatcacaga ttttttatgt gtaccgactt tcacagtacg cactttcttt tctttgacat
     1681 tctctgtctg tttcttattc ttcttaaaca tattttctaa gtcctttctt ttattttact
     1741 cgtcctgcac cgattaagtg ttgttgccag taactattat ttaagtctgc atatcctatc
     1801 ggatt
//
LOCUS       DAEPHU010000180         1763 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 01A10CD0081
            SAMN05941466-rid12468953.denovo.184, whole genome shotgun sequence.
ACCESSION   DAEPHU010000180 DAEPHU010000000
VERSION     DAEPHU010000180.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941466
            Sequence Read Archive: SRR6291087
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1763)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1763)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068158.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 22:43:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,892
            CDSs (total)                      :: 3,805
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 87
            rRNAs                             :: 8, 1, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 55
            CDSs (without protein)            :: 55
            Pseudo Genes (ambiguous residues) :: 0 of 55
            Pseudo Genes (frameshifted)       :: 21 of 55
            Pseudo Genes (incomplete)         :: 28 of 55
            Pseudo Genes (internal stop)      :: 16 of 55
            Pseudo Genes (multiple problems)  :: 8 of 55
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1763
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941466-rid12468953.denovo.184"
                     /strain="01A10CD0081"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            108..818
                     /gene="rgaR"
                     /locus_tag="KR231_003814"
     CDS             108..818
                     /gene="rgaR"
                     /locus_tag="KR231_003814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator RgaR"
                     /protein_id="HBH0006115.1"
                     /translation="MFRVVICDDEKIQRSILKEFTEKLLSERCLNYQILEFSCGEDLI
                     SKYPEKIDIIFLDIQMKDINGIEVAKKIRKFDEKVEIIFTTAFSEYAPQGYEVRAYRY
                     LVKPIEYSNFAMGVNLCIDNLQRKKERYIVLNSKKGFNRILIDSILYVETVKRDLVVH
                     TIGRDYKANMSMKQAEKLLCENGFFRCHTSFIVNLRRIEDLRDNTITINEQFIPISKY
                     RLKDLKVALTSLLCDIMY"
BASE COUNT          700 a          143 c          249 g          671 t
ORIGIN      
        1 tcgacaattt aaatttataa agaaatttaa atttgaaagc tagtgagtac agtttggaaa
       61 ttgaaataaa gtaaactaaa tgatatttta gatttggagg tgatattatg ttcagggtag
      121 ttatatgtga tgacgaaaaa atacaaagaa gcatactaaa agagtttaca gaaaaacttt
      181 tgtctgaaag atgtctaaat tatcaaatac tggaattttc ctgtggagaa gatttaatat
      241 ccaaataccc agaaaaaatt gatattatat ttttagatat ccaaatgaaa gatatcaatg
      301 gaattgaggt ggctaaaaaa ataagaaagt ttgatgaaaa agtagaaatt atatttacaa
      361 cggctttttc agagtatgcc ccccaaggtt atgaagttcg tgcttataga tatttagtaa
      421 agcctataga gtatagtaac tttgcaatgg gtgtaaatct ttgtattgat aaccttcaaa
      481 gaaagaagga gcgttatata gttttaaata gtaaaaaagg atttaataga atactgatag
      541 attctatttt atatgttgaa actgtaaaga gagatttagt tgtacataca ataggtagag
      601 attataaagc taatatgagc atgaaacaag cagaaaaatt actgtgtgaa aatggctttt
      661 ttagatgtca tacaagtttt attgttaatt taagaagaat agaagatctt agggataata
      721 cgattactat taatgaacaa tttataccta taagtaagta tagacttaaa gatttaaaag
      781 tagcattaac aagcttgtta tgtgatataa tgtattaatt ttaaaaaggt aattgaaaat
      841 atcgtaaaaa agatttaatg tcatcacagg gctattgatt gaaactgtct taatatataa
      901 aatgttattt atattaagac agttttatta tgcaaaatag cagtttatag acttttaata
      961 tggtttaata tgtatatgta gagtttccat tataatagca tgattattaa ttagtagctt
     1021 gattatcaat atactattat tgatttttat atgtattata tgtattttta gaatatgatt
     1081 acctttttaa aataatgact atttataaaa ctctatagat atttgtttca tttagctatg
     1141 catactttaa ttaattatat taatatttaa tggagtacaa tataaatatt aaagcgacat
     1201 cttatagttt attgaaccta tagtaatgaa ttaataaata gtttaattct atgaaaagat
     1261 ttccttttat gcaatttatt tattgaaata tgatataata tataaaggtg taagtattag
     1321 ttgttaaaat aatatttata ttagttttta tgcatacttg gtataagttt ttcatatatt
     1381 gattaaaatt gatgttgatt tattattttt agtatttttt caccttttga ttcatacttt
     1441 gtagaatggt gtattttcta aaactgatta taagacaagt tcattcaaat tagcattttt
     1501 atatcatata aataattgtt ccccctaaat aagatttaga tgtatagtat taaaatcaaa
     1561 aagtataaaa taaaattgat gcttaatcat agataaatat taataaaata tacaagggga
     1621 ttgtctaata aaaagataat ctcctttttt acaaataatt ctaaattgtg atataaatct
     1681 aaaaatttta tcttaacatt taaccattta atgataataa ttgatataat aaatataaat
     1741 taaatatatg gtgtacttat ttt
//
LOCUS       DAEPHU010000181         1723 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 01A10CD0081
            SAMN05941466-rid12468953.denovo.185, whole genome shotgun sequence.
ACCESSION   DAEPHU010000181 DAEPHU010000000
VERSION     DAEPHU010000181.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941466
            Sequence Read Archive: SRR6291087
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1723)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1723)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068158.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 22:43:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,892
            CDSs (total)                      :: 3,805
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 87
            rRNAs                             :: 8, 1, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 55
            CDSs (without protein)            :: 55
            Pseudo Genes (ambiguous residues) :: 0 of 55
            Pseudo Genes (frameshifted)       :: 21 of 55
            Pseudo Genes (incomplete)         :: 28 of 55
            Pseudo Genes (internal stop)      :: 16 of 55
            Pseudo Genes (multiple problems)  :: 8 of 55
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1723
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941466-rid12468953.denovo.185"
                     /strain="01A10CD0081"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            224..964
                     /locus_tag="KR231_003815"
     CDS             224..964
                     /locus_tag="KR231_003815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-protein phosphatase"
                     /protein_id="HBH0006116.1"
                     /translation="MKNFRDLGGNKTEDGRTVKKGLFYRSAKLSNLSENDIKILKELN
                     IKYIFDYRSDEEARKHPSTIISNIKNIRIPAMRELEESGGSFGSIEDMIDGLFEKDGA
                     FNMLNNSYYNLPINNPSYKKLVELIRDYSNLPILNHCTAGKDRTGVGSAIILMILGVS
                     RENIMKDYLKSNDFADKEIERFIEYKPKFKDIPKENLKYIFGVNEEYMKTAFRRIDEE
                     YISVEAYLYGEFNLNKEEIRKLRNQYLE"
     gene            976..>1723
                     /locus_tag="KR231_003816"
     CDS             976..>1723
                     /locus_tag="KR231_003816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH domain-containing protein"
                     /protein_id="HBH0006117.1"
                     /translation="MSLNITARQINIIKILLNSKDTISGIALSQEIGCSSKTIQNEIK
                     DINKQLRNGKILSIRGVGYKLEGSFDEVNLNSNLYDDVDRVEYIIRKILTLSNEEKNT
                     IKLEDLADSMYVSVSTVKNDLKEVKRMLEKYSISVKSKHKQGICVLESEDKILNCIVD
                     LSNKRDNQLSLNDFLNDDIKERKLLIKKLLLDILNENGLVLTDIEFKSVLNNILVMLS
                     RHKYNEKEFIENYIENYRSKRSSILENEQNK"
BASE COUNT          785 a          114 c          288 g          536 t
ORIGIN      
        1 acagaaaata tactactgta tattgattat aaactataaa gcttatgtaa agtaaataaa
       61 ttatgtaaaa tttaggttaa ttttgtataa agagatactt ttatatttta caattaataa
      121 ccaaatacta aaaaatattt taaataaaga acttaaaatt gtgataaaat taatttatag
      181 atattaaaaa aagtataata tatggttttt aagaggtgct aagatgaaaa attttagaga
      241 tttaggtggg aacaaaactg aggatggcag aactgtaaag aagggattat tttataggtc
      301 tgcaaaatta tcaaatctaa gtgaaaatga tataaagatt ttaaaagagt taaatattaa
      361 atatatattt gattatagaa gtgatgaaga agctcgtaaa catccatcaa caataatatc
      421 aaatataaaa aatataagaa taccagcaat gagagagcta gaagaatcag gaggaagttt
      481 tggttctatt gaagatatga ttgatggatt gtttgaaaaa gatggtgcat ttaatatgtt
      541 aaataatagt tactataatt tgcctataaa taatccgtca tataaaaaat tagtagaact
      601 tataagagac tattctaatt taccaatatt aaatcattgt acagctggta aggatagaac
      661 tggtgtgggg agtgctataa ttcttatgat tttaggggta tcgagagaga atataatgaa
      721 agattatcta aaaagtaatg attttgcaga taaagagata gaaagattta tagaatataa
      781 gcctaaattt aaggacattc caaaagaaaa tttgaaatat atatttggtg taaatgaaga
      841 gtatatgaaa actgcattta gaagaattga tgaagaatac attagtgtag aagcatattt
      901 atatggagaa tttaatttaa ataaagaaga aataagaaaa ttaagaaatc aatatctaga
      961 gtaaaaggtg agtttatgag tttaaatata acagcaagac agataaatat aataaaaata
     1021 ttgttaaatt caaaagatac aattagtggt attgccttaa gtcaagagat aggatgttct
     1081 tcaaaaacta tacaaaatga aataaaggat attaataaac aacttagaaa tggtaaaatt
     1141 ttgtcaataa gaggagttgg ttataaacta gaaggaagtt ttgatgaggt aaatctaaat
     1201 agcaatctct atgatgatgt agatagagta gaatatataa tcagaaaaat attaacctta
     1261 agtaatgaag aaaaaaatac tataaaactt gaagatttag ccgattctat gtatgtaagt
     1321 gtttcaacag taaaaaatga tttaaaagaa gtaaaaagaa tgttggaaaa gtattcaata
     1381 tcagttaaat ctaagcataa acaaggtata tgtgttttag aaagtgaaga taagatatta
     1441 aattgtatag ttgacttaag caataagaga gataatcaat tgagtttaaa tgatttttta
     1501 aatgatgata taaaggaaag aaaactatta ataaaaaaat tattattaga catattaaat
     1561 gaaaatggat tagtattaac tgatatagaa tttaagagtg tgttaaataa tatattagtt
     1621 atgttaagca gacataagta taatgaaaaa gaatttatag agaattatat agaaaattat
     1681 aggagcaaaa gaagctcaat tttagaaaat gaacaaaaca aag
//
LOCUS       DAEPHU010000182         1675 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 01A10CD0081
            SAMN05941466-rid12468953.denovo.186, whole genome shotgun sequence.
ACCESSION   DAEPHU010000182 DAEPHU010000000
VERSION     DAEPHU010000182.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941466
            Sequence Read Archive: SRR6291087
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1675)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1675)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068158.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 22:43:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,892
            CDSs (total)                      :: 3,805
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 87
            rRNAs                             :: 8, 1, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 55
            CDSs (without protein)            :: 55
            Pseudo Genes (ambiguous residues) :: 0 of 55
            Pseudo Genes (frameshifted)       :: 21 of 55
            Pseudo Genes (incomplete)         :: 28 of 55
            Pseudo Genes (internal stop)      :: 16 of 55
            Pseudo Genes (multiple problems)  :: 8 of 55
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1675
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941466-rid12468953.denovo.186"
                     /strain="01A10CD0081"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            87..1577
                     /locus_tag="KR231_003817"
     CDS             87..1577
                     /locus_tag="KR231_003817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S dicluster domain-containing protein"
                     /protein_id="HBH0006118.1"
                     /translation="MFQFETQIHKLRHDVLTAIARLGKEDNLTREAMDNIQYEIIKGE
                     KPTYRCCVYKERAIISERVNVSMGLQPGQDKIDLDTMDIEEDEQIIYILEAACDSCPI
                     NEFTVTDICRGCLAHRCKEACKFGAITHVGGMAYINHELCKACGMCKKACQYDAISEV
                     VRPCKSVCPTNALGFDRENMKAMIHEDKCLNCGACMSACPFGAISDKSLIAPVARKLV
                     QKEKMYAVVAPAITGQVEANVTYGQIKNAIKSLGFVDVLEAACGADAVTVHESLEFAE
                     RMEKGEAFMTNSCCPGFVGYIEKTYPNHVGKISSTVSPMIASGRFIKSHEPDAKVVFI
                     GPCTAKKSEAAKKELKGAVDYVLTFEEIMALFEAFDIDLAKCSNEDIDDASIFGRGFG
                     AAGGLTKAIENYLAEKGIGVNFEPVKISGSREIKKTMTMANLGKLEGNFIEGMMCEGG
                     CINGSGKFLSGAKVKATFDRKNSQSTKKSVLANTKIKDFSNINLEK"
BASE COUNT          634 a          179 c          349 g          513 t
ORIGIN      
        1 atataatatt ttatgtatat attaataaaa ggacatattg tgttataatg gtatcgtata
       61 aaatcattta cgggggtggt attaaaatgt ttcaatttga aacacaaata cacaaattaa
      121 gacatgatgt tttaactgca atagctagac ttggaaaaga agataacctt accagagaag
      181 caatggataa tattcagtat gaaataataa aaggtgagaa acctacatac agatgctgtg
      241 tttataaaga aagagctata atatctgaga gagtaaatgt aagtatgggg ttacaaccag
      301 gtcaagataa gatagattta gatacaatgg atatagaaga agatgaacaa attatatata
      361 ttttggaagc tgcatgtgac agttgtccaa taaatgaatt tacagtaaca gatatttgta
      421 gaggatgtct agcacataga tgtaaagaag cttgtaaatt tggagctata acacatgtcg
      481 gaggaatggc ctatataaat catgaattat gtaaggcttg tggaatgtgt aaaaaagctt
      541 gtcaatatga tgccatctca gaggttgtta gaccatgtaa gagtgtttgt ccaactaatg
      601 ccttaggatt tgatagagaa aatatgaaag ctatgataca tgaggataaa tgtttaaact
      661 gtggagcatg tatgtcagca tgtccatttg gagcaatatc tgataagagt ttgatagctc
      721 ctgtagctag aaagttagtt caaaaagaga aaatgtatgc ggtggtagct ccagctataa
      781 caggtcaagt tgaagcaaat gttacatatg gtcaaataaa aaatgctata aaatcactag
      841 gatttgttga tgtattagaa gcagcttgtg gagcagatgc agttacagtt catgaaagct
      901 tagaatttgc tgaaagaatg gaaaagggag aagcttttat gacaaattct tgttgtccag
      961 gatttgttgg ttatatagaa aaaacatacc caaatcatgt aggaaaaata tcttctacag
     1021 tgtctcctat gatagctagt ggtagattta taaaaagtca tgaaccagat gctaaagttg
     1081 tattcatagg accatgtaca gccaaaaaga gtgaggcagc taagaaagaa ttaaaaggag
     1141 ctgttgatta tgtacttact tttgaagaaa taatggcatt atttgaggca tttgatatag
     1201 acttggctaa gtgttcaaat gaagatatag atgatgcatc aatttttgga agaggttttg
     1261 gagctgctgg tggtcttaca aaagctatag aaaattatct tgctgaaaaa ggtattggtg
     1321 ttaattttga acctgtaaag atttctggtt caagagaaat caagaaaact atgactatgg
     1381 ctaatttagg aaagctagaa ggtaatttta tagaaggaat gatgtgtgaa ggtggttgta
     1441 taaatggttc tggtaaattc ttatcaggtg caaaggttaa agccactttt gatagaaaaa
     1501 attctcaatc aactaagaaa agtgtcttag caaatacaaa gataaaagat tttagtaata
     1561 taaatttaga aaaataaaga taatacaaag caacaaaaat acatattgtt aatagagttg
     1621 ttctaagttg aggtttaact tttggacaac tctattttta tttatatatt taatt
//
LOCUS       DAEPHU010000183         1446 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 01A10CD0081
            SAMN05941466-rid12468953.denovo.187, whole genome shotgun sequence.
ACCESSION   DAEPHU010000183 DAEPHU010000000
VERSION     DAEPHU010000183.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941466
            Sequence Read Archive: SRR6291087
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1446)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1446)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068158.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 22:43:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,892
            CDSs (total)                      :: 3,805
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 87
            rRNAs                             :: 8, 1, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 55
            CDSs (without protein)            :: 55
            Pseudo Genes (ambiguous residues) :: 0 of 55
            Pseudo Genes (frameshifted)       :: 21 of 55
            Pseudo Genes (incomplete)         :: 28 of 55
            Pseudo Genes (internal stop)      :: 16 of 55
            Pseudo Genes (multiple problems)  :: 8 of 55
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1446
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941466-rid12468953.denovo.187"
                     /strain="01A10CD0081"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     repeat_region   282..1365
                     /inference="COORDINATES: alignment:crt:1.2"
                     /inference="COORDINATES: alignment:pilercr:v1.02"
                     /rpt_family="CRISPR"
                     /rpt_type=direct
                     /rpt_unit_range=348..376
                     /rpt_unit_seq="atttacataccacatagttaatataaaac"
BASE COUNT          581 a          204 c          146 g          515 t
ORIGIN      
        1 gcatctcctt atatttaaat tatagtatga atattcataa atttcaatct atttataagg
       61 taattatttt ttatatctaa tatcttgtca ttaagtttta ttatatatat ttataaattt
      121 ttcaatactt tttataatta ttctactttt atattttaat cattaaaact aaagtcaatg
      181 ttatctggta attatttact acaaatgcta aaaaataatt atattttaaa ggataaaatg
      241 ctgtataaat tattggggta ttttacctat acttgttgca aatttacata ccacgtagtt
      301 aatataaaac aagatgtttt taaaaataaa cttaatatag atattgaatt tacataccac
      361 atagttaata taaaacttta atcatatatc agataggtca caacttaaga gtgatttaca
      421 taccacatag ttaatataaa acaacttctc atattccaga taattgttat tttacgaaat
      481 ttacatacca catagttaat ataaaacctg tagatttgcc tgtttcgata ttgctcatgt
      541 gtgaatttac ataccacata gttaatataa aactctcttg tttcttctgt taattttatt
      601 ataccttcat tatttacata ccacatagtt aatataaaac gcgttatatt gttgtataaa
      661 accgattaaa gttcaattta cataccacat agttaatata aaacttgcaa catattgttt
      721 tatcgttgct gggtctttaa aaccatttac ataccacata gttaatataa aactaagcga
      781 tattagagag cgcaaggcat agcggagcaa atttacatac cacatagtta atataaaact
      841 ttaattttaa ccaccccctt tcactaataa aaaaagattt acataccaca tagttaatat
      901 aaaacaagac gctatacaag aggtaatttg aaagcaatct aatttacata ccacatagtt
      961 aatataaaac gttgcatatg tatgtctaag agcatgaaat ttaattttat ttacatacca
     1021 catagttaat ataaaacttc tattaagtgt aagcaaaacg cttggaatat gaaatttaca
     1081 taccacatag ttaatataaa acttatacac aaatacaact tgaagaagcg ctaaagagat
     1141 ttacatacca catagttaat ataaaaccta atgagtacat agataaacgt acaggagagg
     1201 ttaatttaca taccacatag ttaatataaa acgttgataa ttttcgtttg tatacttttt
     1261 ataatttaaa atttacatac cacatagtta atataaaaca taaagattta gaaaaagaaa
     1321 aagttaaaat tttggaattt acataccaca tagttaatat aaaaccccaa aataaactaa
     1381 gtattttcag tacttacaca catacaactc tctcaaattt gcagtgaacc atgagtagtg
     1441 caattg
//
LOCUS       DAEPHU010000184         1431 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 01A10CD0081
            SAMN05941466-rid12468953.denovo.190, whole genome shotgun sequence.
ACCESSION   DAEPHU010000184 DAEPHU010000000
VERSION     DAEPHU010000184.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941466
            Sequence Read Archive: SRR6291087
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1431)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1431)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068158.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 22:43:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,892
            CDSs (total)                      :: 3,805
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 87
            rRNAs                             :: 8, 1, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 55
            CDSs (without protein)            :: 55
            Pseudo Genes (ambiguous residues) :: 0 of 55
            Pseudo Genes (frameshifted)       :: 21 of 55
            Pseudo Genes (incomplete)         :: 28 of 55
            Pseudo Genes (internal stop)      :: 16 of 55
            Pseudo Genes (multiple problems)  :: 8 of 55
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1431
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941466-rid12468953.denovo.190"
                     /strain="01A10CD0081"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            47..1339
                     /locus_tag="KR231_003818"
     CDS             47..1339
                     /locus_tag="KR231_003818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HBH0006119.1"
                     /translation="MIEWFLCKKMLDYTSEKRISNKKINFCVVGIIVFADIIYFFDVP
                     PNIRVIISMIITIAFYKISYDVGFIKSVLISLIYWMLLIATDALSISLTVWLNSINDM
                     SSMGTGDIYRIESIILGKILLIVSLLLYRALKIKLNIEINKRTLFYIVIPIVANIASF
                     FVIFEYIFNPGSGSLIHNFQFVMISVVLLISSITLVLIAKKLQQYNTLVVENNMIKNT
                     LKYENEYYEDIEKKYLKTRLLSHDMKNHILCINAMIKKGIDVTSYLNNLQVEIQSNDL
                     LFNTGNFILDAILSEKKEVCDKNDIELKIGINFSCCEAVELVDICHIFSNILDNAIEA
                     CNKIDSGNRVICVKGDVMQNFYLIRVENTKMNKIITKNGDILTDKKGSLHGLGIKSVK
                     NSVNKYGGNVVIEYDDKKFVVKIAIPLRNVKKAVNHVI"
BASE COUNT          544 a          111 c          239 g          537 t
ORIGIN      
        1 gataaagtca agcttatttt ggaatatttt cattgcgata tcctttatga tagaatggtt
       61 tctttgtaag aaaatgctag attatacaag tgagaaaagg atttctaaca aaaaaataaa
      121 cttttgtgtg gtaggtatta ttgtttttgc tgacataata tatttttttg atgtacctcc
      181 aaatataaga gtaattatat ctatgataat tactattgca ttttataaaa tctcatatga
      241 tgtggggttt ataaagtctg tattaatatc cttaatttat tggatgttac taatcgccac
      301 agatgctttg agtatatctt taacagtttg gcttaattct ataaatgaca tgagtagtat
      361 ggggacggga gatatataca gaattgagtc tataatattg ggaaagatac ttttgattgt
      421 gtctttgctt ttatatagag ccttaaagat aaaacttaat atagaaataa ataaaaggac
      481 attattttat atagttattc ctatagtcgc taatatagca tctttttttg taatttttga
      541 atacatattt aatccagggt ctggtagctt aatacataat ttccaattcg ttatgatttc
      601 tgttgtattg cttatatcaa gtatcacttt agttttaatt gctaaaaaat tacagcaata
      661 taatacttta gttgtagaaa ataatatgat taaaaatact ttgaagtatg aaaatgagta
      721 ttatgaagat atagaaaaga aatatttaaa aactagatta ctaagtcatg atatgaaaaa
      781 tcacatcttg tgtataaatg ctatgattaa aaaaggtatt gatgttactt cttatttaaa
      841 taatttgcag gtagaaattc agagtaatga cttgttattt aatactggta attttatatt
      901 agatgctata ttaagtgaaa agaaagaggt ttgtgataag aatgatatag aactaaaaat
      961 aggaataaat tttagttgtt gtgaagctgt tgaattagtg gatatatgtc atatattttc
     1021 aaatatttta gacaatgcaa ttgaggcatg taataaaatt gatagtggaa atagagttat
     1081 ttgtgttaaa ggtgatgtta tgcaaaattt ttatttaata agagttgaaa atactaagat
     1141 gaataagatt attactaaaa atggagatat tttgacagac aaaaaaggtt ctcttcatgg
     1201 acttggaata aaaagtgtaa aaaactctgt aaataagtat ggtggtaatg ttgtaattga
     1261 atatgatgat aaaaaatttg tagttaaaat tgctattcca cttagaaatg tgaagaaagc
     1321 agttaatcat gtgatttaaa tgtatataaa tttgatgtgt agaaatttaa tatataagaa
     1381 ttaatgtata aaagtgatgc atagaagttt aatatataag aattaatgta t
//
LOCUS       DAEPHU010000185         1427 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 01A10CD0081
            SAMN05941466-rid12468953.denovo.191, whole genome shotgun sequence.
ACCESSION   DAEPHU010000185 DAEPHU010000000
VERSION     DAEPHU010000185.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941466
            Sequence Read Archive: SRR6291087
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1427)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1427)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068158.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 22:43:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,892
            CDSs (total)                      :: 3,805
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 87
            rRNAs                             :: 8, 1, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 55
            CDSs (without protein)            :: 55
            Pseudo Genes (ambiguous residues) :: 0 of 55
            Pseudo Genes (frameshifted)       :: 21 of 55
            Pseudo Genes (incomplete)         :: 28 of 55
            Pseudo Genes (internal stop)      :: 16 of 55
            Pseudo Genes (multiple problems)  :: 8 of 55
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1427
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941466-rid12468953.denovo.191"
                     /strain="01A10CD0081"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            237..1109
                     /locus_tag="KR231_003819"
     CDS             237..1109
                     /locus_tag="KR231_003819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HBH0006120.1"
                     /translation="MEETNEMKDSKHLISNIQSQYTRLSKGQKLIAQYILNNYDKVAF
                     MTACKLGETVGVSESTVVRFANALGYSGYPKLQAALQELIKNKLTTVQRVEMAHDYSD
                     DFAILNKVLKSDIDNIRSTLEEIDERAFKEASNKLLRARKIYILGMRSSFVVAQYLGF
                     YLDIILDNVHIIRMDMGDAFEQIVRINEEDVIVAISFPRYSKKSYQIVNYAKEKGAHV
                     ISLTDSLFAPVASLADNTLLVKSNMASFVDSLVPALSISNALAISVGMKEKEDIKQHF
                     DDLEQIWKRYSVYE"
BASE COUNT          584 a          150 c          224 g          469 t
ORIGIN      
        1 aaattgaaaa atttaaaaga aatattggat aaatattaaa aaatgcaagg aaagatggta
       61 taataaattt aatcgaaaat actatgtgaa gtataaggta cagaaaagtt agaattttat
      121 gagtttaaga agctatgata aaaactaaga tgaaattgag ataaaaaata aaatttttag
      181 agaaaaagac agtgttaata aaacaaaata gtttatataa ctaaaaggag aaaaaaatgg
      241 aagaaacaaa tgaaatgaag gacagtaaac atttgatatc aaatatacaa tctcaatata
      301 cgagattgag taagggtcaa aaacttatag cacaatacat tttaaataat tatgataaag
      361 ttgcatttat gactgcatgt aaattgggtg aaactgtagg agtaagtgag tctacagttg
      421 taagatttgc aaatgcatta ggttatagtg gatatcctaa attacaagct gcacttcaag
      481 aactcataaa aaataaacta actacagtac aaagagttga aatggcacat gattattccg
      541 atgattttgc aatactaaac aaagttttaa aaagtgatat agataatata aggtctacac
      601 tagaagaaat tgacgagaga gcgtttaaag aagcttctaa caaactttta agagcgagaa
      661 aaatatatat acttggaatg aggagttctt ttgtagtagc tcaatattta ggtttttact
      721 tagatataat acttgacaat gttcatataa ttagaatgga tatgggagat gcttttgagc
      781 agattgtaag aataaatgaa gaagatgtaa tagttgctat tagtttccct cgttattcta
      841 agaaatctta tcaaattgtc aattatgcta aagaaaaagg agcccatgta atatcattaa
      901 cagatagctt atttgcgcca gtagcatcac ttgcagataa cactcttcta gttaagagta
      961 atatggcttc atttgtagat tctctagttc cagctcttag tatttcaaat gctcttgcta
     1021 tatctgttgg gatgaaggaa aaagaagata ttaaacagca ttttgatgat ttagagcaaa
     1081 tttggaaaag atattctgtg tatgagtaaa gtttgtgtat taataaggct atgaaattga
     1141 gaatcatagc cttattaata aatactagat tatcacttaa aaaataaatt ttcgtttaaa
     1201 taatacaaat aaatatttcg agactcaaaa cataaagatg tattctgaat atatctttac
     1261 tacatcaact aatttattaa agaaagcatt tcccttcatg gagagtgctt tttttatttc
     1321 tctaaacaat atcatttcct taattaacaa ttataaaatt aattttattt gtatttaagt
     1381 atataatatc ttattaaaat tctattaaaa tatgtatttc tatcttt
//
LOCUS       DAEPHU010000186         1408 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 01A10CD0081
            SAMN05941466-rid12468953.denovo.192, whole genome shotgun sequence.
ACCESSION   DAEPHU010000186 DAEPHU010000000
VERSION     DAEPHU010000186.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941466
            Sequence Read Archive: SRR6291087
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1408)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1408)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068158.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 22:43:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,892
            CDSs (total)                      :: 3,805
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 87
            rRNAs                             :: 8, 1, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 55
            CDSs (without protein)            :: 55
            Pseudo Genes (ambiguous residues) :: 0 of 55
            Pseudo Genes (frameshifted)       :: 21 of 55
            Pseudo Genes (incomplete)         :: 28 of 55
            Pseudo Genes (internal stop)      :: 16 of 55
            Pseudo Genes (multiple problems)  :: 8 of 55
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1408
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941466-rid12468953.denovo.192"
                     /strain="01A10CD0081"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            257..973
                     /locus_tag="KR231_003820"
     CDS             257..973
                     /locus_tag="KR231_003820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBH0006121.1"
                     /translation="MNQNILVVDDDREIVDAIEFYLRPDNFNVLKAYDGLEALDILIE
                     NDIKLIIMDVMMPNLDGLKTTLKIREKRNIPIILLSAKSEDMDKIIGLNMGADDYITK
                     PFNPLELTARVKSQLRRYINLGDFSNTNNSNDTNYILKSGGLELNTDTKIVSLDGEEI
                     KMTPLEYKILTLLMSRKGKIFSSHEIYENVWNEDAYSCERTIAVHIRRIREKIEINPK
                     EPKYLKVVWGIGYKIEKLNY"
BASE COUNT          542 a          159 c          198 g          509 t
ORIGIN      
        1 taatatatgt ttaaacctaa aaaattaata aaccaaaata acataagaag tgtgatagat
       61 taccctagat attttcataa acttttacct tcagattaat atgggcgtct atacttttaa
      121 atttactata tgcattgaca atatattaaa agtactagtt tttatttcat aatgaacggg
      181 cttactgttt tctaatacct ctttttggta taaaataaaa attggttaaa aataaaattt
      241 caagggggtt aataaattga atcaaaatat attggttgta gatgatgata gagagatagt
      301 tgatgctata gagttctatt tgagacctga taactttaat gttttaaagg catatgatgg
      361 acttgaagca ttggacatac taatcgaaaa tgatattaaa ttaataataa tggatgtaat
      421 gatgcccaat ttagatgggc ttaaaactac acttaaaata agagaaaaaa ggaatatacc
      481 aataattctc ttatctgcaa aatcagaaga tatggacaaa attataggtc ttaatatggg
      541 tgctgatgac tatataacta aaccatttaa tccactagaa cttactgctc gagtaaaatc
      601 tcaacttaga aggtatataa atttaggtga ttttagtaat acaaataact caaatgatac
      661 taattatatt ctaaaaagtg gtggcctaga gctaaataca gatacaaaaa tagtttcttt
      721 agatggtgag gaaattaaaa tgacaccact tgaatataaa atacttacac ttcttatgtc
      781 acgaaaaggt aaaattttct cttctcatga gatttatgaa aatgtctgga atgaggatgc
      841 ttatagttgt gagagaacta ttgctgttca tattagaaga attagagaaa agattgaaat
      901 taatccaaaa gaaccaaaat atttaaaggt ggtgtggggc attggttaca aaattgaaaa
      961 acttaattat taatgattct aaagcaaaat ttattttatt attattactg tttctattag
     1021 tttctatatt atttgaagca gtttatgatt tgaataataa cttttctaat attaattatt
     1081 attatagaga gtttgctctc ccttattttt attttttcgg tactcctgta catttgtcaa
     1141 aagtagaatt agagtttgtc tgcataggta ttatattatc aagtttttta ttgactatac
     1201 tatgttttac attgtataaa aaaaataaac aaactaaagt caaattctta gagaatgtca
     1261 taaacctttt ttctaaggta aaaatagaac ttacacttat attaactttg atactattaa
     1321 ccttaaggtt tcatgcattt acaagtaata aaatgtttta caacactaat ttaataatct
     1381 acaattttat aattatatct atagtcta
//
LOCUS       DAEPHU010000187         1349 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 01A10CD0081
            SAMN05941466-rid12468953.denovo.193, whole genome shotgun sequence.
ACCESSION   DAEPHU010000187 DAEPHU010000000
VERSION     DAEPHU010000187.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941466
            Sequence Read Archive: SRR6291087
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1349)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1349)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068158.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 22:43:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,892
            CDSs (total)                      :: 3,805
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 87
            rRNAs                             :: 8, 1, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 55
            CDSs (without protein)            :: 55
            Pseudo Genes (ambiguous residues) :: 0 of 55
            Pseudo Genes (frameshifted)       :: 21 of 55
            Pseudo Genes (incomplete)         :: 28 of 55
            Pseudo Genes (internal stop)      :: 16 of 55
            Pseudo Genes (multiple problems)  :: 8 of 55
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1349
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941466-rid12468953.denovo.193"
                     /strain="01A10CD0081"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            <1..>1349
                     /locus_tag="KR231_003821"
     rRNA            <1..>1349
                     /locus_tag="KR231_003821"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
BASE COUNT          357 a          292 c          408 g          292 t
ORIGIN      
        1 caaggtttcc aggggaaggt tcgtccgccc tgggttagtc gggacctaag ctgaggccga
       61 aaggcgtagg tgatggacaa caggttgata ttcctgtact accgataacc gtttgagaga
      121 agggatgaca cagtaggata agctaagcac actgttggtt atgtgtgccc aagcattgag
      181 gcagtcaaag taggcaaatc cgctttgata atgctgggat gtgatgggga gcgaaattta
      241 gtagcgaagt agctgatttc acactgtcaa gaaaagtctc tatcgaggtt aaaggtaccc
      301 gtaccgcaaa ccgacacagg tgggtgagga gagtatccta aggccagcga gagaactgtt
      361 gttaaggaac tcggcaaaat gaccccgtaa cttagggata aggggtgcca ccatcaggtg
      421 gccgcagaga ataggcccaa gcgactgttt accaaaaaca taggtttctg ctaagtcgca
      481 agacgatgta taggagctga cgcctgcccg gtgctggaag gttaagggga tctgttagag
      541 caatcgaagc agtgaactta agccccagta aacggcggcc gtaactataa cggtcctaag
      601 gtagcgaaat tccttgtcgg gtaagttccg acccgcacga aaggcgtaac gatttgggca
      661 ctgtctcaac aacagactcg gtgaaattgt aattccggtg aagatgccgg atacctgcga
      721 caggacggaa agaccccatg gagctttact gtagcttgac attgggtctt ggtactacat
      781 gtacaggata ggtgggaggc tttgaaacca ggacgccagt tttggcggag ccatccttgg
      841 gataccaccc ttgtagtact gggactctaa ccataggcca tgaatctggt cttgggacac
      901 tgtcaggtgg gcagtttgac tggggcggtc gcctcccaaa aggtaacgga ggcgctcaaa
      961 ggttctctca gtacggtcgg aaatcgtacg tagagtgtaa aggcaaaaga gagcttgatt
     1021 gcaagacata caggtcgagc aaggatgaaa atcggactta gtgatccggt ggttctgcgt
     1081 ggaagggcca tcgctcaacg gataaaagct accctgggga taacaggctt atctccccca
     1141 agagtccaca tcgacgggga ggtttggcac ctcgatgtcg gctcatcaca tcctggggct
     1201 gtagtaggtc ccaagggttg ggctgttcgc ccattaaagt ggtacgcgag ctgggttcag
     1261 aacgtcgtga gacagttcgg tccctatccg tcgcaggcgt aggaaatttg agaagacctg
     1321 tccttagtac gagaggaccg ggatggacg
//
LOCUS       DAEPHU010000188         1337 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 01A10CD0081
            SAMN05941466-rid12468953.denovo.194, whole genome shotgun sequence.
ACCESSION   DAEPHU010000188 DAEPHU010000000
VERSION     DAEPHU010000188.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941466
            Sequence Read Archive: SRR6291087
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1337)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1337)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068158.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 22:43:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,892
            CDSs (total)                      :: 3,805
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 87
            rRNAs                             :: 8, 1, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 55
            CDSs (without protein)            :: 55
            Pseudo Genes (ambiguous residues) :: 0 of 55
            Pseudo Genes (frameshifted)       :: 21 of 55
            Pseudo Genes (incomplete)         :: 28 of 55
            Pseudo Genes (internal stop)      :: 16 of 55
            Pseudo Genes (multiple problems)  :: 8 of 55
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1337
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941466-rid12468953.denovo.194"
                     /strain="01A10CD0081"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            27..101
                     /locus_tag="KR231_003822"
     tRNA            27..101
                     /locus_tag="KR231_003822"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:59..61,aa:Thr,seq:tgt)
     gene            116..200
                     /locus_tag="KR231_003823"
     tRNA            116..200
                     /locus_tag="KR231_003823"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:150..152,aa:Tyr,seq:gta)
     gene            210..293
                     /locus_tag="KR231_003824"
     tRNA            210..293
                     /locus_tag="KR231_003824"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:244..246,aa:Leu,seq:tag)
     gene            323..399
                     /locus_tag="KR231_003825"
     tRNA            323..399
                     /locus_tag="KR231_003825"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:357..359,aa:Arg,seq:tct)
     gene            407..482
                     /locus_tag="KR231_003826"
     tRNA            407..482
                     /locus_tag="KR231_003826"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:440..442,aa:Gln,seq:ttg)
     gene            571..659
                     /locus_tag="KR231_003827"
     tRNA            571..659
                     /locus_tag="KR231_003827"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:605..607,aa:Ser,seq:tga)
     gene            663..738
                     /locus_tag="KR231_003828"
     tRNA            663..738
                     /locus_tag="KR231_003828"
                     /product="tRNA-Phe"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:696..698,aa:Phe,seq:gaa)
     gene            745..818
                     /locus_tag="KR231_003829"
     tRNA            745..818
                     /locus_tag="KR231_003829"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:779..781,aa:Met,seq:cat)
     gene            833..909
                     /locus_tag="KR231_003830"
     tRNA            833..909
                     /locus_tag="KR231_003830"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:867..869,aa:Ile,seq:cat)
     gene            933..1009
                     /locus_tag="KR231_003831"
     tRNA            933..1009
                     /locus_tag="KR231_003831"
                     /product="tRNA-Pro"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:967..969,aa:Pro,seq:tgg)
     gene            1017..1093
                     /locus_tag="KR231_003832"
     tRNA            1017..1093
                     /locus_tag="KR231_003832"
                     /product="tRNA-His"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1051..1053,aa:His,seq:gtg)
     gene            1102..1177
                     /locus_tag="KR231_003833"
     tRNA            1102..1177
                     /locus_tag="KR231_003833"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1135..1137,aa:Lys,seq:ttt)
     gene            1185..1258
                     /locus_tag="KR231_003834"
     tRNA            1185..1258
                     /locus_tag="KR231_003834"
                     /product="tRNA-Cys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1217..1219,aa:Cys,seq:gca)
     gene            1265..1336
                     /locus_tag="KR231_003835"
     tRNA            1265..1336
                     /locus_tag="KR231_003835"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1297..1299,aa:Asn,seq:gtt)
BASE COUNT          320 a          309 c          355 g          353 t
ORIGIN      
        1 ccccttccag gtcgccaaaa taaaatgctg gtgtggctca acggtagagc agctgacttg
       61 taatcagcag gttgtaggtt cgattcctat caccagctcc atgtaaaatt aatacggagg
      121 atttcccgag cggccaaagg gggcagactg taaatctgtt gtcatcgact tcggtggttc
      181 gaatccacca tcctccacca aaaaaatgcg cggatgtggc ggaattggca gacgcactag
      241 acttaggatc tagcgccatt ggcgtggggg ttcgactccc ttcatccgca ccatttttgt
      301 ttgatataca tatatatatt gtgggtgcat agctcagctg gatagagcaa cgcccttcta
      361 aggcgtgtgt ccggggttcg aatccctgtg cgctcaccac atatattggg gattagccaa
      421 gtcggtaagg cacatgactt tgactcatgt atgcgtaggt tcgagtcctg catccccagc
      481 caaatgatgt attactaagc tatatttgaa ttatttttat tttaaatata gttaggttca
      541 attttagaat aagtttaagt atccgaatgt ggagaggtgt ccgagtggtt taaggagctg
      601 gtcttgaaaa ccagtgactt cgaaaggggc cgtgggttcg aatcccaccc tctccgccaa
      661 atgcccagat agctcagtcg gtagagcagg ggactgaaaa tccccgtgtc ggtggttcga
      721 ttccgcctct gggcaccaaa atatggcggt atagcttagt tggctagagc gttcggttca
      781 tacccgaaag gtcataggtt cgactcctat taccgctact aaaatttaat gtgggccatt
      841 agctcagttg gttagagcgc ccggctcata accggtaggt ctggggttcg agtccctgat
      901 ggcccaccac attaaattaa ttaatataaa ttcgaggtgt agcgcagttt ggtagcgcac
      961 atggtttggg accatggggc cgggggttcg agtcccttca cctcgaccaa tataaggtgg
     1021 gtatagctca gttggttaga gcgccagatt gtggctctgg aggtcgtgag ttcgactctc
     1081 attatccacc ccaattcata tggtctatta gctcagtcgg tagagcacct gacttttaat
     1141 cagggtgtcc cgcgttcgag tcgcggatag atcaccaaaa aggtggcgac atagccaagt
     1201 ggtaaggcag tggactgcaa ctccttgatc cccagttcga atctgggtgt cgcctccaaa
     1261 atattccaag gtagctcaac ggtggagcaa ccggctgtta accggtaggc tgtgggttcg
     1321 agccccaccc ttggagc
//
LOCUS       DAEPHU010000189         1335 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 01A10CD0081
            SAMN05941466-rid12468953.denovo.195, whole genome shotgun sequence.
ACCESSION   DAEPHU010000189 DAEPHU010000000
VERSION     DAEPHU010000189.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941466
            Sequence Read Archive: SRR6291087
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1335)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1335)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068158.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 22:43:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,892
            CDSs (total)                      :: 3,805
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 87
            rRNAs                             :: 8, 1, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 55
            CDSs (without protein)            :: 55
            Pseudo Genes (ambiguous residues) :: 0 of 55
            Pseudo Genes (frameshifted)       :: 21 of 55
            Pseudo Genes (incomplete)         :: 28 of 55
            Pseudo Genes (internal stop)      :: 16 of 55
            Pseudo Genes (multiple problems)  :: 8 of 55
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1335
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941466-rid12468953.denovo.195"
                     /strain="01A10CD0081"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            76..1320
                     /locus_tag="KR231_003836"
     CDS             76..1320
                     /locus_tag="KR231_003836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0006122.1"
                     /translation="MENNLNTAKRNNTELLQNDSLKVNLQIGVDFTLLSKSLKAFYKK
                     EKDFYCIALAPCNVSSEKANRKISIYNMIKEINILIESITDKNELLSEELFTNNLSEF
                     YDESLDEIYIDLKQAYLYIKKNTDSLNIEDSIEYVFDVDISNDIKAKENPLINFNSLS
                     LVVWSGETKHILQQMNILDLEDIHSYSIENNTNITIYENNTLQYKFDEESENIKDSSI
                     DIIEQMLILPDDLNYDKDEVENMKNRLAKINIKYLQTLKEKDIKIKLINSNLTDEPEF
                     SDLKYQLPPCWVRSGKTWKDVPGIYRNNSIVAKIGYSNPSYANVHSSKNLELHETAHA
                     IDKNVLNKKSNSEEFMEVFAQERYKLYDPKQVAHAYISKFIEEFFAESFVHYYLDEDS
                     KNTLKENCPLTYDFLEKLELNY"
BASE COUNT          587 a          151 c          177 g          420 t
ORIGIN      
        1 aattataatt ttcaaaaaaa caaattgaca catataaaaa aattatgata ccctaataaa
       61 aagggggcaa tgattatgga aaacaattta aatacagcta aaagaaataa tactgaatta
      121 ttacaaaatg actcacttaa ggtcaactta cagataggtg tagactttac acttttatca
      181 aaatcactta aagcctttta taaaaaagaa aaagattttt attgcattgc tcttgcgcca
      241 tgcaatgtat ctagtgaaaa agcaaataga aaaataagta tttacaatat gataaaagaa
      301 attaatattt taattgaaag tataactgat aaaaatgaac ttttaagtga agaactcttt
      361 actaataatt tatcagaatt ttatgacgaa tctttagatg agatttatat agacttaaaa
      421 caagcgtatt tatatattaa aaagaataca gatagtctta acatagaaga ctcaattgaa
      481 tatgtatttg atgtagatat aagcaatgat ataaaagcaa aagaaaatcc actaattaat
      541 tttaattcac tttctttagt agtgtggagt ggcgaaacaa aacatatttt acaacaaatg
      601 aatattttag atttagagga tattcactct tattctatag aaaataatac aaatataact
      661 atctatgaaa ataatactct tcaatataaa tttgatgaag aatctgaaaa tataaaagac
      721 agtagtatag atataattga acaaatgctt atacttcctg atgacttgaa ttatgataaa
      781 gatgaagttg aaaatatgaa aaacagactt gcaaaaataa atattaaata tttacagaca
      841 cttaaagaaa aggatataaa aataaaatta ataaattcaa atctaactga tgaaccagaa
      901 tttagtgatt taaaatatca attacctcca tgttgggtaa gatcaggcaa gacttggaaa
      961 gatgtacctg gtatatatag aaataattct atagtggcta aaataggtta tagtaaccct
     1021 agctatgcaa atgtacattc atcaaaaaat ttagaattac atgaaactgc acatgctata
     1081 gataaaaatg ttttaaataa aaaatcaaat tctgaagaat ttatggaagt atttgctcag
     1141 gaaagatata agctttatga ccctaagcaa gttgcacatg catatataag caagtttata
     1201 gaagaatttt ttgcagaatc atttgtacat tattatcttg atgaagattc aaaaaatact
     1261 ttaaaggaaa attgtcctct aacatatgat tttcttgaaa aacttgaact aaactattaa
     1321 gtgcgctaat atcca
//
LOCUS       DAEPHU010000190         1288 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 01A10CD0081
            SAMN05941466-rid12468953.denovo.196, whole genome shotgun sequence.
ACCESSION   DAEPHU010000190 DAEPHU010000000
VERSION     DAEPHU010000190.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941466
            Sequence Read Archive: SRR6291087
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1288)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1288)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068158.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 22:43:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,892
            CDSs (total)                      :: 3,805
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 87
            rRNAs                             :: 8, 1, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 55
            CDSs (without protein)            :: 55
            Pseudo Genes (ambiguous residues) :: 0 of 55
            Pseudo Genes (frameshifted)       :: 21 of 55
            Pseudo Genes (incomplete)         :: 28 of 55
            Pseudo Genes (internal stop)      :: 16 of 55
            Pseudo Genes (multiple problems)  :: 8 of 55
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1288
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941466-rid12468953.denovo.196"
                     /strain="01A10CD0081"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            460..837
                     /locus_tag="KR231_003837"
     CDS             460..837
                     /locus_tag="KR231_003837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
                     /protein_id="HBH0006123.1"
                     /translation="MKEEILIEKLLRVELIVMEYLWKKDTLMPKKKIVKEIKQIYGWH
                     KSTIKILLKRLVDKRYLARYIINFQSYYKIIIDNKEYYTFKKKVLKSSKSIKIMHSLT
                     TIHKNVSKEKLDLLDEYYRNLKE"
     gene            942..1288
                     /locus_tag="KR231_003838"
                     /pseudo
     CDS             942..1288
                     /locus_tag="KR231_003838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430377.1"
                     /note="frameshifted; internal stop; incomplete; missing
                     C-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
BASE COUNT          582 a          114 c          171 g          421 t
ORIGIN      
        1 ataaaatcat ctaactgtgt atctataaaa tcaaaataat tatatgaact atcagtataa
       61 taagtcaaaa tatgtataca tgaatacata ttttaaaaga tatatattat tacataccta
      121 aaaaactttc ataaaaacaa aaataaaata tgcttttagt aacttgttaa cataacttat
      181 aatttatttt ataggcatta gcctatatag ctttgtgcta ctaaatttct ttgattctag
      241 cgatttagtg ctattctaca actaaaataa tacaatagag ctatttattg tttggtagca
      301 ttgtttgcaa attaaacaaa tttatatata tgaatattat tttacgttta aaaaaacaga
      361 ctaaatatgt agaatatttg gtaaaactta cctctagttt ttgtcttaaa aagctcctat
      421 tattaattta agttagaaga attaaggaag tgacataaat tgaaagaaga aatattaata
      481 gaaaaattat taagagtaga attaatagta atggagtatt tatggaaaaa agacactcta
      541 atgcctaaaa aaaaaattgt aaaagaaata aaacagattt atggatggca taaaagtaca
      601 ataaaaatac tactaaaaag gctagttgat aaaaggtatt tggctagata tattataaat
      661 tttcaatctt attataaaat aataatagat aataaagaat attatacttt taagaaaaag
      721 gtactaaaat ctagtaaaag cataaaaata atgcattcac ttaccactat acataaaaat
      781 gtaagtaaag agaagttaga cctattagat gagtattata gaaacttaaa agaatgatat
      841 agtaaaaatc gaatgtaatt atttacctta attcctttgt ttgtaaaact ttattgatat
      901 agaatttgac atatacataa attggtaaag ggatgtatac tatgaaaatt agtaaattac
      961 cagaagcgga attaaaagtt atgagatata tttgggaatc agaaaaggta ttaataccaa
     1021 gagaaatcac caagtctatg gaacaaaaat atgaatggaa agatacaact atatttacag
     1081 tattaaaaag attactaaag aagagagttt ttagaagcgg agaaaataga taagtgtaca
     1141 cactataatg tattagtaaa aaaaaataat atcagagatt ttaaacaaaa gaatttttaa
     1201 agaatacaca taaaaattca atattaagtt taatgtcagc actatgtagt aaggatgatg
     1261 aagtagatgg tgatatttta aatttatt
//
LOCUS       DAEPHU010000191         1278 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 01A10CD0081
            SAMN05941466-rid12468953.denovo.197, whole genome shotgun sequence.
ACCESSION   DAEPHU010000191 DAEPHU010000000
VERSION     DAEPHU010000191.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941466
            Sequence Read Archive: SRR6291087
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1278)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1278)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068158.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 22:43:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,892
            CDSs (total)                      :: 3,805
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 87
            rRNAs                             :: 8, 1, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 55
            CDSs (without protein)            :: 55
            Pseudo Genes (ambiguous residues) :: 0 of 55
            Pseudo Genes (frameshifted)       :: 21 of 55
            Pseudo Genes (incomplete)         :: 28 of 55
            Pseudo Genes (internal stop)      :: 16 of 55
            Pseudo Genes (multiple problems)  :: 8 of 55
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1278
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941466-rid12468953.denovo.197"
                     /strain="01A10CD0081"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            complement(330..707)
                     /locus_tag="KR231_003839"
     CDS             complement(330..707)
                     /locus_tag="KR231_003839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
                     /protein_id="HBH0006124.1"
                     /translation="MTITKIPPAELKVMKFIWSSDFTVASKDVIEAMEKLYNWKQTTT
                     LTLLSRLVNKQFLSARKIDRHTHYTVLIGEEEYLHFETKTFLDNMHGSSIESFMKSLF
                     KKGVNEEELNSVEKWVKDIKKDE"
     gene            1048..>1278
                     /locus_tag="KR231_003840"
     CDS             1048..>1278
                     /locus_tag="KR231_003840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Arm DNA-binding domain-containing protein"
                     /protein_id="HBH0006125.1"
                     /translation="MNAFIRKRNKNYVVYLEFEDEKTGKRKQKNMGTFDKKREASKRL
                     NEVKESLYNDGFLVPSEITVSEFLLDFLNKYSE"
BASE COUNT          517 a          158 c          120 g          483 t
ORIGIN      
        1 tattgtatac ttatcttacc ctagaaataa tcaaaacaaa aataaaatta tgccctttat
       61 atctaaaaca attaatttac atgattaata tacaaaaatt ctgactttta aattcgtata
      121 caatatcaaa ctaaaataat attaatgaca aacccaatat aaattaaatt caaacaggtt
      181 tgattttaca tcaaacttat tgtattaata ttaaataaca agacaaaaat atttataaaa
      241 atcacaaatt ttacataaaa ctttatattt gattcattta actaattatt gtaaaaacta
      301 tttattttat gataattaac tacaccaaat tattcatctt ttttaatatc tttaacccat
      361 ttttcaacag agttcaattc ttcttcattt accccctttt tgaacaagga tttcataaaa
      421 ctctcaatag aacttccatg catattatct aaaaaagttt ttgtttcaaa atgtaaatac
      481 tcttcttctc caataagaac tgtataatgt gtatgtctat caatttttct tgcacttaag
      541 aattgcttat ttactaatct tgataaaagt gttagtgttg tagtttgctt ccaattatat
      601 agtttttcca tagcttcaat gacatctttt gatgctactg taaaatctga actccaaata
      661 aatttcatga cttttaattc tgctggtggt atcttagtaa tagtcatatg attttacact
      721 cctctcaaac ttctacataa ttaaatacta tattaataga cttttcgagt caaaggtttt
      781 atttaaaata tctcatccaa atttattaat acaaaaaatt tatattttta ttcaaaatta
      841 aacacacaat ctattaatat aaagataaat atctattcta taagtataac agattatcaa
      901 attaaaattc taatatttga cataatatat acatttttta aataaatata tacaatgtat
      961 taaaatgtat gcaactctat ttcaaaatta ttttgtgata tatatatgtt ataataaatg
     1021 tataaaattt tgattggtgg gttatatatg aatgcattta ttagaaaaag aaataaaaac
     1081 tatgttgttt acctggaatt tgaagatgaa aaaacaggta aaagaaaaca aaaaaatatg
     1141 ggtacttttg ataaaaaaag ggaagcaagt aaaagactaa atgaggtaaa agaaagctta
     1201 tataatgatg gttttttagt accaagcgaa attacagtgt cagaatttct attagatttt
     1261 ctaaataaat atagtgaa
//
LOCUS       DAEPHU010000192         1229 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 01A10CD0081
            SAMN05941466-rid12468953.denovo.199, whole genome shotgun sequence.
ACCESSION   DAEPHU010000192 DAEPHU010000000
VERSION     DAEPHU010000192.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941466
            Sequence Read Archive: SRR6291087
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1229)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1229)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068158.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 22:43:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,892
            CDSs (total)                      :: 3,805
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 87
            rRNAs                             :: 8, 1, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 55
            CDSs (without protein)            :: 55
            Pseudo Genes (ambiguous residues) :: 0 of 55
            Pseudo Genes (frameshifted)       :: 21 of 55
            Pseudo Genes (incomplete)         :: 28 of 55
            Pseudo Genes (internal stop)      :: 16 of 55
            Pseudo Genes (multiple problems)  :: 8 of 55
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1229
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941466-rid12468953.denovo.199"
                     /strain="01A10CD0081"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            complement(265..771)
                     /locus_tag="KR231_003841"
     CDS             complement(265..771)
                     /locus_tag="KR231_003841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavin reductase"
                     /protein_id="HBH0006126.1"
                     /translation="MGFREVKIEELQFNPFTKIGKEWLLITAGDSEKFNTMTASWGGV
                     GVYWGKNVVTTYIRPQRYTKEFVDSNDTFTIAFFDETYREALNICGTISGRDINKIEK
                     AGLTPYFVDDTVAFEEANMIIVCKKLYHGNMPPENFDAKENDKKWYPEKDYHTMYISE
                     IIKVLVKE"
BASE COUNT          433 a          172 c          106 g          518 t
ORIGIN      
        1 attaagtgtt tctagttagc ataaaaatac ttataaagta tactcaaata tttcaaataa
       61 atacttttat tcaaataaat ctctacttat ataagtgctt atataaataa aaagatgaac
      121 tatagtaaat atagttcatc ttttttataa tagtatttat ttaaaattaa tatttattta
      181 gttagtagca tctacttaga tatcagataa gaaagcacag tcatttactt ataataagtt
      241 cttttcatat attttttatt ataattattc ttttacaaga acttttataa tttctgaaat
      301 gtacatagta tgatagtctt tctctggata ccatttttta tcattttctt tagcatcaaa
      361 gttttctggt ggcatattac catgatatag ctttttacat actataatca tattagcttc
      421 ttcaaaagct accgtatcat ccacaaaata tggtgtaagt cctgcttttt ctattttatt
      481 tatatctcta ccagaaatag tgccacaaat atttaaagct tctctatacg tttcatcaaa
      541 gaaggcaatt gtaaatgtat cattactatc tacaaattct tttgtatatc tctgtggtct
      601 tatgtaagtt gtaacaacat ttttacccca atagactcca acaccacccc agctagcagt
      661 cattgtgtta aacttttctg aatcaccagc tgttataagt aaccattctt tgccaatctt
      721 agtaaatgga ttaaactgta attcctcaat ttttacttct ctaaaaccca tgacttcatc
      781 ctacccttca ttttttaatt atataaatta attgttaaaa atttgaatat atgtactctt
      841 ataatactga cttttgattg tcctacataa ttcatgtaaa ttataataca acaaatcaat
      901 tactttcgca ataagtagtt ttcatatttt ataagtgtaa aatatagata aaatatattg
      961 attataaagt atataatata tttttaaacc taaagcaata tacaataaaa aaatgtagaa
     1021 agtaagtatc tctctacatt ttttattgta tattattttt atattaattt aattttatct
     1081 tgattcagtt ttataaaaaa ttgttataat tgtcaagttc tactctatta tttataattt
     1141 cttatatctt attaacaaca tttaagttat tacatttatt tatatatatt ttttcattat
     1201 ctaagtcttc atcaaacatt tttattata
//
LOCUS       DAEPHU010000193         1174 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 01A10CD0081
            SAMN05941466-rid12468953.denovo.200, whole genome shotgun sequence.
ACCESSION   DAEPHU010000193 DAEPHU010000000
VERSION     DAEPHU010000193.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941466
            Sequence Read Archive: SRR6291087
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1174)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1174)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068158.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 22:43:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,892
            CDSs (total)                      :: 3,805
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 87
            rRNAs                             :: 8, 1, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 55
            CDSs (without protein)            :: 55
            Pseudo Genes (ambiguous residues) :: 0 of 55
            Pseudo Genes (frameshifted)       :: 21 of 55
            Pseudo Genes (incomplete)         :: 28 of 55
            Pseudo Genes (internal stop)      :: 16 of 55
            Pseudo Genes (multiple problems)  :: 8 of 55
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1174
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941466-rid12468953.denovo.200"
                     /strain="01A10CD0081"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            272..1003
                     /locus_tag="KR231_003842"
     CDS             272..1003
                     /locus_tag="KR231_003842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0006127.1"
                     /translation="MLSKKNVSLIILVIILSLLTAIFIFNNKNTNNKLKEVTKNNEEI
                     VPKNLEGLSIEQLIEIRDKAIDKNLEGLREFGEDSVKKRKDSILNFEFGLVAFVNKNY
                     SNLTEKEKLIRQINIVNYENSINDIMDPSGSFFELANQNYQVNEFLLKNGKDYKEWSY
                     EGLDFLIDHLEELCKFVDFDVKDVIDIIDPTIKTDLSEEQKKSLNDKLKKISSSDTLS
                     EEVKKEIKNWENNLNNLNMNKNNSN"
BASE COUNT          525 a          101 c          144 g          404 t
ORIGIN      
        1 atattactta ttataaaact taaaacatat aaaaatatat tttaaagcaa taattttatt
       61 ttacttatta aatatttgga gttattaaaa tcttttctat ctaaaaaata ttgatattaa
      121 atatctaata agaaaattta ataagaaaaa tatagattat atcaaaaaaa tattctatta
      181 taatctttag aacaaacagt agtaaatgtt atcttcataa acaaatttat ttttcacaag
      241 tacaatactt atttaaaaaa ggaggtttaa tatgttaagt aaaaaaaatg taagtttaat
      301 tattttagta ataattttaa gtttattaac tgctatattt attttcaata ataaaaatac
      361 taacaataaa ttgaaagaag ttactaagaa taatgaagaa atagtaccta aaaacttaga
      421 aggtttaagt atagaacaat taatagagat tagagataaa gccattgata aaaatttaga
      481 aggtcttagg gaatttggag aagattcagt aaaaaaacgt aaagattcaa ttttaaactt
      541 tgaatttgga ttagtagctt ttgttaacaa gaattatagc aacttaacag aaaaagagaa
      601 attaataaga caaattaata ttgttaacta tgaaaactct ataaatgata taatggatcc
      661 ttcaggttca ttctttgaat tagcaaatca gaattaccaa gtgaatgagt ttctattaaa
      721 aaacggaaaa gattataaag aatggtcata tgaaggtcta gattttctaa ttgatcatct
      781 agaagaactg tgcaaatttg ttgattttga tgtaaaagat gtaatagata ttattgatcc
      841 tacaataaaa acagaccttt cagaggaaca aaagaaatct ttgaatgata aattaaagaa
      901 aatatcttca agtgatactt taagtgaaga agttaaaaag gagataaaaa actgggaaaa
      961 caatttaaat aatttaaata tgaataaaaa taattctaat taattttctc ataagaaaaa
     1021 tgcttatatc gtgataatgt gaaatgtaca taattataaa caaaaaaggg gctgtgacac
     1081 taaaaaatag tgctacgccc ttttttattt gtaataatca tcaatacaaa ttattttatt
     1141 atatgtaatt atttatgtct taaccaattt tatc
//
LOCUS       DAEPHU010000194         1026 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 01A10CD0081
            SAMN05941466-rid12468953.denovo.201, whole genome shotgun sequence.
ACCESSION   DAEPHU010000194 DAEPHU010000000
VERSION     DAEPHU010000194.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941466
            Sequence Read Archive: SRR6291087
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1026)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1026)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068158.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 22:43:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,892
            CDSs (total)                      :: 3,805
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 87
            rRNAs                             :: 8, 1, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 55
            CDSs (without protein)            :: 55
            Pseudo Genes (ambiguous residues) :: 0 of 55
            Pseudo Genes (frameshifted)       :: 21 of 55
            Pseudo Genes (incomplete)         :: 28 of 55
            Pseudo Genes (internal stop)      :: 16 of 55
            Pseudo Genes (multiple problems)  :: 8 of 55
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1026
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941466-rid12468953.denovo.201"
                     /strain="01A10CD0081"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            307..774
                     /locus_tag="KR231_003843"
     CDS             307..774
                     /locus_tag="KR231_003843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HBH0006128.1"
                     /translation="MKFLNVLIVVEDIEKSKKFYYDVLGLKVICDFGENVVLEGNISL
                     QEKKLWLEFINKSDSEVKFNGNDAELYFEEDYFDTFVERLSTMRDIDYVHLAIEHRWG
                     QRAIRFYDLDGHIIEVGETMSSVCRRFLDSGLSIDEVAKRMDVTVEYIESVLE"
BASE COUNT          387 a           69 c          173 g          397 t
ORIGIN      
        1 ttaatattat tagtgtatat taatattctc ttgaaattaa aaaaacatag atatttcagt
       61 aatctaaaat agtctacaaa aataacagtt ttagcaaaat taataagaat acatatagat
      121 ttaaacctaa aagtatgaat gtgtctgttt tttacaagat taaaatttat attatatgat
      181 acaattaact taactatttc aataagactt ataatttttt tctttatact agaccttatt
      241 gaaaccttta tagtttaatt ctaattatat attataaata aagtatgtgt atattaagga
      301 ggtaatatga agtttttaaa tgttttaata gtagttgaag atattgagaa atcaaaaaag
      361 ttttattatg atgttttggg gttaaaggta atctgtgatt ttggagaaaa tgttgtatta
      421 gaagggaata tatcattaca agaaaaaaag ctttggttag agtttattaa taagagtgac
      481 agtgaagtta agttcaatgg aaatgatgct gagctgtatt ttgaggaaga ttattttgat
      541 acttttgttg aaagattgag tacaatgaga gatatagatt atgttcatct agctatagag
      601 cataggtggg gtcaaagagc aattagattt tatgatttag atgggcatat tattgaggtt
      661 ggagaaacta tgtcatctgt gtgtagacgt tttttagata gtggtctttc aatagatgag
      721 gtagctaaaa gaatggatgt aactgtcgaa tatattgaat cagttttaga atagatggat
      781 tatattaaag taaaactata ttttgtatag aagtaagggc tgtaagtaaa cttgtatgga
      841 aacaaattta cttacagttt ttgtttttgt aagatacaga atataatatt tgttataatt
      901 ttatttggat ttttaaaaag tgcatgattt tccttacata ttataataga atttaatatt
      961 tattggatga tttaaattta gaaaaatata agtattagct tataaaagat aattatactt
     1021 actatc
//
LOCUS       DAEPHU010000195          983 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 01A10CD0081
            SAMN05941466-rid12468953.denovo.202, whole genome shotgun sequence.
ACCESSION   DAEPHU010000195 DAEPHU010000000
VERSION     DAEPHU010000195.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941466
            Sequence Read Archive: SRR6291087
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 983)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 983)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068158.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 22:43:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,892
            CDSs (total)                      :: 3,805
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 87
            rRNAs                             :: 8, 1, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 55
            CDSs (without protein)            :: 55
            Pseudo Genes (ambiguous residues) :: 0 of 55
            Pseudo Genes (frameshifted)       :: 21 of 55
            Pseudo Genes (incomplete)         :: 28 of 55
            Pseudo Genes (internal stop)      :: 16 of 55
            Pseudo Genes (multiple problems)  :: 8 of 55
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..983
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941466-rid12468953.denovo.202"
                     /strain="01A10CD0081"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            95..712
                     /locus_tag="KR231_003844"
     CDS             95..712
                     /locus_tag="KR231_003844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YmfQ family protein"
                     /protein_id="HBH0006129.1"
                     /translation="MDKEINLINYLPQILQDKEEYIKVFNVENKEIKTLHEKLNDLSS
                     DQFLEDLTPSGIKRWEKIMSITPKSNESLEDRRFRIFSKYISKLPYSERFLRNWLDSI
                     VGEGNYELTINNATYNIHLESDARNQDWFEEVHSFVSSIKPCNMTLDYTRVLVSKDNY
                     MNFGITTLIGQEITIYPWSPPDIETYGEIDVLTGNGVGYQEITIF"
     gene            724..>983
                     /locus_tag="KR231_003845"
     CDS             724..>983
                     /locus_tag="KR231_003845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HBH0006130.1"
                     /translation="MAIDKSYYTIITDVGKAKIANASVTGNKVGFVKIQLGDGGGSEY
                     TPTESQTALKNVVWEGNIGNTTTDETAPNCIILESLIPSSVGG"
BASE COUNT          399 a          108 c          197 g          279 t
ORIGIN      
        1 gatggagtgt tagatattac aaacacaatg ataaatgatg ttaaatctaa tctaacaata
       61 gatagtaaca gtatagtagt gagaggtgag gtagttggat aaagagatta atctaataaa
      121 ttacttacca caaattctac aagataaaga agaatatata aaagtattta atgtagaaaa
      181 caaagaaata aaaacactac atgaaaaatt aaatgaccta tcaagtgacc agtttttaga
      241 ggatttaact ccaagtggta taaaaagatg ggaaaagata atgtctataa ctcctaaaag
      301 taatgagagt ttagaagata gaaggtttag gatttttagt aaatatataa gtaaactacc
      361 ttactcagag agatttttaa ggaactggct agatagtata gttggagaag gcaattatga
      421 attaactatt aataatgcta cttataatat acatcttgaa agtgatgcta gaaatcaaga
      481 ttggtttgag gaggttcatt cttttgtaag tagtattaaa ccttgcaaca tgactttaga
      541 ttacactaga gtgcttgtaa gtaaagacaa ttatatgaat tttggtataa caaccctaat
      601 aggtcaagaa ataactatat acccttggag tccaccagat atagaaactt atggagaaat
      661 tgatgtatta actggcaatg gagttggata ccaagagata acaatatttt aggaggtgat
      721 atattggcta tagataaaag ttattacact ataattacag atgtagggaa agcaaagata
      781 gcaaatgcaa gtgtcacagg taataaagtg ggatttgtaa aaattcaact tggtgatgga
      841 ggagggagtg aatatactcc aactgagagt cagacagctc tcaaaaatgt ggtatgggaa
      901 ggcaatatcg gaaatacaac tacagatgaa actgcaccaa attgtataat attagagagt
      961 ttaataccat caagtgtagg cgg
//
LOCUS       DAEPHU010000196          980 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 01A10CD0081
            SAMN05941466-rid12468953.denovo.203, whole genome shotgun sequence.
ACCESSION   DAEPHU010000196 DAEPHU010000000
VERSION     DAEPHU010000196.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941466
            Sequence Read Archive: SRR6291087
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 980)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 980)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068158.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 22:43:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,892
            CDSs (total)                      :: 3,805
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 87
            rRNAs                             :: 8, 1, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 55
            CDSs (without protein)            :: 55
            Pseudo Genes (ambiguous residues) :: 0 of 55
            Pseudo Genes (frameshifted)       :: 21 of 55
            Pseudo Genes (incomplete)         :: 28 of 55
            Pseudo Genes (internal stop)      :: 16 of 55
            Pseudo Genes (multiple problems)  :: 8 of 55
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..980
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941466-rid12468953.denovo.203"
                     /strain="01A10CD0081"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            <1..802
                     /locus_tag="KR231_003846"
     CDS             <1..802
                     /locus_tag="KR231_003846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HBH0006131.1"
                     /translation="QDLHPVHIQNYIDKLSYKLNPQSIKIHINILKLAIKRAYRLKLI
                     KENVMDSIEAPRYKKFKNEIYDREQMIKLLDLAKNTEMELPINLAIGLGLRISEVLGL
                     TWDNIDFEENTITVNKITSRINGSVILKEPKTESSVRKISSPKELMSLLKEYKIKQNK
                     NLLKSSIRNNNNLLFFNKKCEPIAEDVMSKKFKRFLEKNELPHIRFHDLRHSHVTLLI
                     NSKVPIKVISERVGHSNISTTLSVYSHVLKEMDKEASDKISESLFNAN"
BASE COUNT          408 a          117 c          120 g          335 t
ORIGIN      
        1 acaagactta catccggttc acatacaaaa ctacatagat aaactatctt ataaactaaa
       61 tcctcaatca attaagattc atataaatat attgaaactt gcaataaaaa gagcttatag
      121 actcaaatta ataaaagaaa atgttatgga tagtatagag gctccaagat ataaaaaatt
      181 taaaaatgag atttatgata gagaacaaat gataaaatta ttagatttag caaaaaatac
      241 agaaatggaa ttacctatta atttggctat tggattaggt cttagaattt cagaagtttt
      301 aggtctaact tgggataata ttgattttga agaaaataca ataacagtaa ataagataac
      361 ttcccgaatt aatggttctg ttattctcaa agagccaaag acagaaagct ctgttagaaa
      421 aatatcttct cccaaagaat taatgtcttt attaaaagaa tataaaataa aacagaataa
      481 aaatttatta aaatcttcca ttagaaataa taataatttg ttgtttttca ataagaaatg
      541 tgaacctatt gctgaagatg ttatgagtaa aaaatttaaa agatttttag aaaagaatga
      601 attacctcat attagattcc atgatttaag acactcacat gttactttac ttataaattc
      661 taaagtacct ataaaggtta tatccgagag agtaggacac tcaaatataa gtactactct
      721 aagcgtttat tctcatgtac ttaaagaaat ggataaggag gcttctgaca aaatttctga
      781 aagtttattt aatgctaatt aatattaatt tatcttagct ttaaattagc ttagcttatt
      841 gagatagatt cattaatatt aaatgtatct atctcaaatt aataactact taaataatct
      901 gttttatttt aatttatcgc ctcagttatt atactttttt acgaaaaatt atactttaca
      961 ataaaaaaga tattccctta
//
LOCUS       DAEPHU010000197          965 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 01A10CD0081
            SAMN05941466-rid12468953.denovo.205, whole genome shotgun sequence.
ACCESSION   DAEPHU010000197 DAEPHU010000000
VERSION     DAEPHU010000197.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941466
            Sequence Read Archive: SRR6291087
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 965)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 965)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068158.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 22:43:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,892
            CDSs (total)                      :: 3,805
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 87
            rRNAs                             :: 8, 1, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 55
            CDSs (without protein)            :: 55
            Pseudo Genes (ambiguous residues) :: 0 of 55
            Pseudo Genes (frameshifted)       :: 21 of 55
            Pseudo Genes (incomplete)         :: 28 of 55
            Pseudo Genes (internal stop)      :: 16 of 55
            Pseudo Genes (multiple problems)  :: 8 of 55
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..965
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941466-rid12468953.denovo.205"
                     /strain="01A10CD0081"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            22..903
                     /locus_tag="KR231_003847"
     CDS             22..903
                     /locus_tag="KR231_003847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4300 family protein"
                     /protein_id="HBH0006132.1"
                     /translation="MKKRLIIMILSVVLVLSSILTIFAYSNIKYNNNKLIYSNMIDKK
                     TQNSVKEILKENKINEKDIDTFIKAVNNYNKLQVKILQNNINISKSGYSSINAKQVPY
                     NLEKLQDNWVKKFPDYMDVNCRITAFRLFKDFINSNKKFTGDSIDLNVDLDTIMNNKD
                     AKFSIKDVEKFINFFSAIPAKDTDDTIKISEQIKNEWKKRKISFKNNKNISIINGFLR
                     YPETKNVFIGHTGICIKTKNGILFLEKYGVTSPYQVTKFKNKEDVKNYMFNRLKMSEG
                     EIELPDPIIMENDKLMK"
BASE COUNT          446 a           98 c          117 g          304 t
ORIGIN      
        1 atttaaaaag gagaattaaa tatgaaaaaa agattaataa taatgatatt gtctgttgtc
       61 ttagtactat caagtatact tacgatattt gcatattcaa atattaaata taataataat
      121 aaattgatat attctaatat gatagataaa aaaactcaaa atagtgtaaa ggaaatccta
      181 aaagaaaata aaattaatga aaaagacata gatacattta ttaaagcagt caacaattat
      241 aataaattgc aagttaaaat acttcaaaat aatataaata tatctaaatc tggatattct
      301 tcaatcaatg caaaacaagt tccatataac ctagaaaaat tgcaagataa ttgggtgaaa
      361 aaattccctg attatatgga tgtaaattgt agaataactg cttttagact ttttaaagat
      421 tttataaatt caaataagaa atttactgga gactctattg atttgaatgt cgacttggac
      481 actataatga ataataaaga tgctaaattt agcatcaaag atgtagaaaa atttatcaac
      541 ttcttttctg caataccagc taaagataca gatgatacaa tcaaaatttc agaacaaata
      601 aaaaatgaat ggaaaaaaag aaaaatatct tttaaaaata ataaaaatat atctattata
      661 aatggatttc ttcgttatcc agaaactaaa aacgtattta taggtcatac aggcatatgt
      721 attaaaacta aaaatggcat tctattttta gaaaaatacg gtgttacatc accttatcaa
      781 gttactaaat ttaaaaataa agaagatgta aaaaattata tgtttaatag attgaagatg
      841 tcagaaggtg aaattgaatt acctgaccct ataataatgg aaaacgataa acttatgaaa
      901 taataacttt aaacgcaaaa taatatttat aattactaag tcaatataat agagaaggtc
      961 tatag
//
LOCUS       DAEPHU010000198          762 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 01A10CD0081
            SAMN05941466-rid12468953.denovo.207, whole genome shotgun sequence.
ACCESSION   DAEPHU010000198 DAEPHU010000000
VERSION     DAEPHU010000198.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941466
            Sequence Read Archive: SRR6291087
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 762)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 762)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068158.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 22:43:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,892
            CDSs (total)                      :: 3,805
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 87
            rRNAs                             :: 8, 1, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 55
            CDSs (without protein)            :: 55
            Pseudo Genes (ambiguous residues) :: 0 of 55
            Pseudo Genes (frameshifted)       :: 21 of 55
            Pseudo Genes (incomplete)         :: 28 of 55
            Pseudo Genes (internal stop)      :: 16 of 55
            Pseudo Genes (multiple problems)  :: 8 of 55
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..762
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941466-rid12468953.denovo.207"
                     /strain="01A10CD0081"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            343..>762
                     /gene="cdtR"
                     /locus_tag="KR231_003848"
     CDS             343..>762
                     /gene="cdtR"
                     /locus_tag="KR231_003848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LytTR family response regulator CdtR"
                     /protein_id="HBH0006133.1"
                     /translation="MDILIFDNDVCFGMKLKEKINNILIKEGFDNDVVRLYHNANLLL
                     KELTEKNKVRIYFIVVDAKYKISNELCDGLWIAQKIRESDYISPIIFLTNHIEMILGI
                     FDYRLEVMDFILKHDMEIAESKIKACIKIAHKRYIKEK"
BASE COUNT          319 a           59 c           88 g          296 t
ORIGIN      
        1 taaataattc ttctaaaaaa aatacctata aattttattt tctgaaatac atagttataa
       61 ctatttttat cacgtataag aataaaaatt ccagaaaatt tttattatct aagttaatat
      121 aaaacatatt atttaatata aataaatttt ttataataat atattgattt aatttacttt
      181 attattgtaa actataagta taagatatac tatataaaca agcataaata taccttaatt
      241 ctaactatcc ttaatcttat ttatctccta gtgttatttt atgtattttc tataaaatac
      301 ttttgttttt ttacttttga attttttata ggagggtatt tagtggatat attaatcttt
      361 gataatgatg tttgttttgg aatgaaacta aaagaaaaaa taaataatat tttaataaaa
      421 gaaggttttg ataatgatgt tgtaagatta tatcataatg caaatttgtt attaaaagag
      481 cttactgaaa aaaataaagt aagaatatat tttatagttg tagacgcaaa atataagata
      541 agtaatgaat tatgtgatgg attatggata gcacaaaaaa ttagagaatc agattatatt
      601 agtccaatca tatttcttac aaatcatata gaaatgattt tagggatctt cgattatagg
      661 ttagaagtta tggactttat actaaaacat gatatggaaa ttgctgaaag taaaataaaa
      721 gcttgtatta aaattgctca caaaagatac attaaagaaa aa
//
LOCUS       DAEPHU010000199          736 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 01A10CD0081
            SAMN05941466-rid12468953.denovo.208, whole genome shotgun sequence.
ACCESSION   DAEPHU010000199 DAEPHU010000000
VERSION     DAEPHU010000199.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941466
            Sequence Read Archive: SRR6291087
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 736)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 736)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068158.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 22:43:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,892
            CDSs (total)                      :: 3,805
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 87
            rRNAs                             :: 8, 1, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 55
            CDSs (without protein)            :: 55
            Pseudo Genes (ambiguous residues) :: 0 of 55
            Pseudo Genes (frameshifted)       :: 21 of 55
            Pseudo Genes (incomplete)         :: 28 of 55
            Pseudo Genes (internal stop)      :: 16 of 55
            Pseudo Genes (multiple problems)  :: 8 of 55
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..736
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941466-rid12468953.denovo.208"
                     /strain="01A10CD0081"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            <1..624
                     /locus_tag="KR231_003849"
     CDS             <1..624
                     /locus_tag="KR231_003849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase large subunit"
                     /protein_id="HBH0006134.1"
                     /translation="AYYRRMQMRKEQDPEGYKVYGLGEWGETGGAILKNYVIHEFTTE
                     FEYFDNMRLSQDFGFNHANVVLRIGFKDGELYICNEIYVHEMDTSEIIKIANSIGLEK
                     TLFMYCDSAEPDRIKMWKNAGYKAKGVKKGPGSVKAQIDYLKQLRIHVHPSCTNTIKE
                     IQQWKWKQDERTGLYLDEPVEFMDDAMAALRYSIDNKLKNNGISFLK"
BASE COUNT          305 a           83 c          147 g          201 t
ORIGIN      
        1 gcttactaca gaagaatgca aatgagaaaa gagcaagacc cagaagggta caaagtctat
       61 ggtcttggag aatggggaga aactggtgga gcaatactta aaaattatgt tatacatgaa
      121 tttactacag aatttgagta ttttgacaat atgaggttat cacaagactt tggatttaac
      181 catgcaaatg tagtacttag aattggcttt aaggatggag agttatatat atgtaacgaa
      241 atatatgtac atgaaatgga tacctcagaa atcataaaga ttgcaaatag tataggttta
      301 gaaaagactc tatttatgta ctgtgatagt gctgaaccag atagaattaa gatgtggaag
      361 aatgcaggat ataaagctaa aggagttaaa aaagggccag gaagtgttaa agctcaaata
      421 gattatttga aacaattaag aatacatgta catcctagtt gcactaatac cataaaagaa
      481 atacaacaat ggaaatggaa acaagacgaa agaactggat tatatcttga tgaaccagtt
      541 gagtttatgg atgatgcaat ggctgctctt agatattcta tagataataa gcttaaaaat
      601 aatggaataa gcttcttaaa gtaaaggagg tgttaaatat ttatataagt gaaacagatt
      661 taataaaagt tcagttaaaa aaagagagca cctttaacct agtaaaagtc atagaacact
      721 acatcttaaa acatag
//
LOCUS       DAEPHU010000200          736 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 01A10CD0081
            SAMN05941466-rid12468953.denovo.209, whole genome shotgun sequence.
ACCESSION   DAEPHU010000200 DAEPHU010000000
VERSION     DAEPHU010000200.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941466
            Sequence Read Archive: SRR6291087
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 736)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 736)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068158.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 22:43:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,892
            CDSs (total)                      :: 3,805
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 87
            rRNAs                             :: 8, 1, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 55
            CDSs (without protein)            :: 55
            Pseudo Genes (ambiguous residues) :: 0 of 55
            Pseudo Genes (frameshifted)       :: 21 of 55
            Pseudo Genes (incomplete)         :: 28 of 55
            Pseudo Genes (internal stop)      :: 16 of 55
            Pseudo Genes (multiple problems)  :: 8 of 55
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..736
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941466-rid12468953.denovo.209"
                     /strain="01A10CD0081"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            <1..624
                     /locus_tag="KR231_003850"
     CDS             <1..624
                     /locus_tag="KR231_003850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase large subunit"
                     /protein_id="HBH0006135.1"
                     /translation="AYYRRMQMRKEQDPEGYKVYGLGEWGETGGAILKNYVIHEFPTE
                     SEYFDNMRLSQDFGFNHANVVLRIGFKDGELYICNEIYAHEMDTSEIIKIANSIGLEK
                     TLFMYCDSAEPDRIKMWKSAGYKAKGVKKGPGSVKAQIDYLKQLRIHVHPSCTNTIKE
                     IQQWKWKQDERTGLYLDEPVEFMDDAMAALRYSIDNKLKNNGISFLK"
BASE COUNT          304 a           85 c          149 g          198 t
ORIGIN      
        1 gcttactaca gaagaatgca aatgagaaaa gagcaagacc cagaagggta caaagtctat
       61 ggtcttggag aatggggaga aactggtgga gcaatactta aaaattatgt tatacatgaa
      121 tttcctacag aatctgagta ttttgacaat atgaggttat cacaagactt tggatttaac
      181 catgcaaatg tagtacttag aattggcttt aaggatggag agttatatat atgtaacgaa
      241 atatatgcac atgaaatgga tacctcagaa atcataaaga ttgcaaatag tataggttta
      301 gaaaagactc tatttatgta ctgtgatagt gctgaaccag atagaattaa gatgtggaag
      361 agtgcaggat ataaagctaa aggagttaaa aaaggaccag gaagtgttaa agctcaaata
      421 gattatttga aacaattaag aatacatgta catcctagtt gcactaatac cataaaagaa
      481 atacaacaat ggaaatggaa acaagatgaa agaactggat tatatcttga tgaaccagtt
      541 gagtttatgg atgatgcaat ggctgcgctt agatattcta tagataataa gcttaaaaat
      601 aatggaataa gcttcttaaa gtaaaggagg tgttaaatat ttatataagt gaaacagatt
      661 taataaaagt tcagttaaaa aaagagagca ccattaacct agtaaaagtc atagaacact
      721 acatcttaaa gcatag
//
LOCUS       DAEPHU010000201          704 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 01A10CD0081
            SAMN05941466-rid12468953.denovo.211, whole genome shotgun sequence.
ACCESSION   DAEPHU010000201 DAEPHU010000000
VERSION     DAEPHU010000201.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941466
            Sequence Read Archive: SRR6291087
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 704)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 704)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068158.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 22:43:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,892
            CDSs (total)                      :: 3,805
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 87
            rRNAs                             :: 8, 1, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 55
            CDSs (without protein)            :: 55
            Pseudo Genes (ambiguous residues) :: 0 of 55
            Pseudo Genes (frameshifted)       :: 21 of 55
            Pseudo Genes (incomplete)         :: 28 of 55
            Pseudo Genes (internal stop)      :: 16 of 55
            Pseudo Genes (multiple problems)  :: 8 of 55
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..704
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941466-rid12468953.denovo.211"
                     /strain="01A10CD0081"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            complement(4..>704)
                     /locus_tag="KR231_003851"
     CDS             complement(4..>704)
                     /locus_tag="KR231_003851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBH0006136.1"
                     /translation="ICEGKKSERVILNDYINTFFYNYNFEYNIKEFENGGDLLKKYPN
                     NVDIIFMDIDLNDENGFNVSKEIKKFDESVRIIFVSSSNKYIKKGYEIGVYRYLEKPL
                     KYSLFKEAISSYLKECYKNEAILSIKCKCKIYFIKVDDILYLEVLKNDLTIHTEKGIY
                     TFKSSMKEIESNLEEHNFFRCHKSYLINLMKVNMLDIENNIVFINQNSIIVSRYKIKL
                     LREKLNSCLVDVII"
BASE COUNT          242 a          103 c           50 g          309 t
ORIGIN      
        1 acctcaaatt attacatcta ccaaacaact atttaacttt tctctcaata attttatctt
       61 ataacgactt acaattattg aattttgatt tataaataca atattatttt ctatatctag
      121 catatttacc ttcattaaat ttataaggta gcttttatga catctaaaaa aattatgttc
      181 ttctagattt gattctattt ctttcatact actcttaaaa gtatatattc ctttttcagt
      241 atgtatagtt aaatcatttt ttaaaacttc taaatataaa atatcatcta cctttatgaa
      301 atatatcttg catttacatt ttatagataa aatagcttca tttttgtagc attcttttaa
      361 atatgatgat attgcttctt taaatagaga gtattttaag ggcttctcta aatatctata
      421 aactcctatc tcataacctt tctttatgta tttatttgat gaggatacaa atataattct
      481 tacactttca tcaaattttt tgatttcttt tgaaacatta aatccatttt catcatttaa
      541 gtctatatcc ataaatatga tatcaacatt attaggatac ttttttaata aatcgcctcc
      601 attttcaaac tctttgatat tgtattcaaa attgtaatta taaaaaaagg tatttatata
      661 atcatttaga attaccctct ctgatttttt accttcgcaa ataa
//
LOCUS       DAEPHU010000202          694 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 01A10CD0081
            SAMN05941466-rid12468953.denovo.212, whole genome shotgun sequence.
ACCESSION   DAEPHU010000202 DAEPHU010000000
VERSION     DAEPHU010000202.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941466
            Sequence Read Archive: SRR6291087
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 694)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 694)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068158.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 22:43:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,892
            CDSs (total)                      :: 3,805
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 87
            rRNAs                             :: 8, 1, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 55
            CDSs (without protein)            :: 55
            Pseudo Genes (ambiguous residues) :: 0 of 55
            Pseudo Genes (frameshifted)       :: 21 of 55
            Pseudo Genes (incomplete)         :: 28 of 55
            Pseudo Genes (internal stop)      :: 16 of 55
            Pseudo Genes (multiple problems)  :: 8 of 55
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..694
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941466-rid12468953.denovo.212"
                     /strain="01A10CD0081"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            230..406
                     /locus_tag="KR231_003852"
     CDS             230..406
                     /locus_tag="KR231_003852"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0006137.1"
                     /translation="MNLKKKEKIVKPVLKKLTEIVLNILSKKILNYAIYAISVLIVTK
                     VVINIDLYISILYY"
     gene            507..>694
                     /locus_tag="KR231_003853"
     CDS             507..>694
                     /locus_tag="KR231_003853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CRISPR-associated endoribonuclease Cas6"
                     /protein_id="HBH0006138.1"
                     /translation="MSRISIFMESCNGKFPNENSMLSVSFIKNILNAENKDFAKNIFN
                     YGEERKNNKQIKDINTAI"
BASE COUNT          314 a           47 c           86 g          247 t
ORIGIN      
        1 ttaaattatt ttttaattta taatgaaata atattatatt agtagttttg gttaacaatg
       61 aggagtttat aaataaggtc atataagtta aattatatcg attttattta aataacccca
      121 tatttattaa ttattagaaa tatattttaa ttattgacta aataataaat actgtaatat
      181 aatggaaata cagtttaata aatataaaaa gagaaagagg gaattttaaa tgaatttgaa
      241 gaaaaaagag aaaatagtta agcctgtttt aaagaagctt acagaaatag tattaaatat
      301 attatcaaaa aaaatattaa actatgctat atatgcaatt tctgttttga tagtaacaaa
      361 agttgttata aatatagatt tgtacatatc catattgtat tattagatat cttatagata
      421 taaaaaatta atagatatat atctattaat tttttatatt acaaatagag aataatgaat
      481 tatactagaa agtaggaggt gaaaatatga gcagaatttc aatttttatg gaatcatgta
      541 atggcaaatt tccaaatgaa aattcaatgt tgtcagtttc ctttataaaa aatattttaa
      601 atgcagaaaa caaagatttt gctaaaaaca tatttaacta tggggaagaa agaaaaaaca
      661 ataagcaaat aaaggatata aatacagcca ttta
//
LOCUS       DAEPHU010000203          636 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 01A10CD0081
            SAMN05941466-rid12468953.denovo.213, whole genome shotgun sequence.
ACCESSION   DAEPHU010000203 DAEPHU010000000
VERSION     DAEPHU010000203.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941466
            Sequence Read Archive: SRR6291087
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 636)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 636)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068158.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 22:43:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,892
            CDSs (total)                      :: 3,805
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 87
            rRNAs                             :: 8, 1, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 55
            CDSs (without protein)            :: 55
            Pseudo Genes (ambiguous residues) :: 0 of 55
            Pseudo Genes (frameshifted)       :: 21 of 55
            Pseudo Genes (incomplete)         :: 28 of 55
            Pseudo Genes (internal stop)      :: 16 of 55
            Pseudo Genes (multiple problems)  :: 8 of 55
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..636
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941466-rid12468953.denovo.213"
                     /strain="01A10CD0081"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            complement(<1..634)
                     /locus_tag="KR231_003854"
     rRNA            complement(<1..634)
                     /locus_tag="KR231_003854"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
BASE COUNT          140 a          175 c          117 g          204 t
ORIGIN      
        1 ctacttaacg taactcgttg gcccgttcta caaaaagtac gcggtcacac aagaaatgtg
       61 cttccacagc ttgtaagtgc agggtttcag gttctatttc actcccctcc cggggttctt
      121 ttcacctttc cctcacggta ctatacgcta tcggtcacta ggtagtattt agccttggag
      181 ggtggtccct cctgcttccc acagggtttc acgtgtcccg tggtactctg gatcatatct
      241 aaagtcttct cgtttaacat acaggactat taccttctgt ggtgggtctt tccaaacctc
      301 ttcaattacg atacctcttc gttatgatat gtccgcaacc ccaataaaga aaactttatt
      361 ggtttgggct aatccgcgtt cgctcgccgc tacttacgga atcgaatttc tttctcttcc
      421 ttcaggtact tagatgtttc agttccctga gttcccctca ttaagctatg tattcactta
      481 atgatactta gacattactc taagtgagtt tcctcattcg gaaatcttcg gatcaaagtt
      541 tacgtgcaac tccccgaagc ttatcgcagc ttatcacgtc cttcatcggc tcctagtgcc
      601 aaggcatccg ccctgcaccc ttaataactt gaccag
//
LOCUS       DAEPHU010000204          611 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 01A10CD0081
            SAMN05941466-rid12468953.denovo.214, whole genome shotgun sequence.
ACCESSION   DAEPHU010000204 DAEPHU010000000
VERSION     DAEPHU010000204.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941466
            Sequence Read Archive: SRR6291087
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 611)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 611)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068158.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 22:43:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,892
            CDSs (total)                      :: 3,805
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 87
            rRNAs                             :: 8, 1, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 55
            CDSs (without protein)            :: 55
            Pseudo Genes (ambiguous residues) :: 0 of 55
            Pseudo Genes (frameshifted)       :: 21 of 55
            Pseudo Genes (incomplete)         :: 28 of 55
            Pseudo Genes (internal stop)      :: 16 of 55
            Pseudo Genes (multiple problems)  :: 8 of 55
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..611
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941466-rid12468953.denovo.214"
                     /strain="01A10CD0081"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            <1..>611
                     /locus_tag="KR231_003855"
     rRNA            <1..>611
                     /locus_tag="KR231_003855"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
BASE COUNT          172 a          126 c          179 g          134 t
ORIGIN      
        1 tttaactgag cgttcagtta cttgacgtag acccgaaacc gggcgaccta cccatgagca
       61 ggatgaagcg aaagtaaaat ttcgtggagg tccgaaccca cgagcgttga aaagctcggg
      121 gatgacttgt gggtagcggt gaaattccaa tcgagcccgg agatagctgg ttctccccga
      181 aatagcttta gggctagcct caaggtgaga gatacggagg tagagcactg aatgtcctag
      241 ggggtattgc acctaccgaa gactatcaaa ctccgaatgc cgtcatctta tacttgggag
      301 tcagactgtg ggtgataaga ttcatagtcg aaagggcaac agcccagatc gtcagctaag
      361 gtccctaaat gtaagttaag tggtaaagga tgtgggattg cacagacaac caggatgttg
      421 gcttagaagc agccactcat tcaaagagtg cgtaatagct cactggtcga gtgatcctgc
      481 gccgaagatt tccggggcta aaacttacta ccgaagctac ggcatcagta atgatgggta
      541 ggggagcttc ccatacgggt tgaagcatga ccgtaaggac atgtggacag tatgggagtg
      601 agaatgttgg c
//
LOCUS       DAEPHU010000205          602 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 01A10CD0081
            SAMN05941466-rid12468953.denovo.216, whole genome shotgun sequence.
ACCESSION   DAEPHU010000205 DAEPHU010000000
VERSION     DAEPHU010000205.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941466
            Sequence Read Archive: SRR6291087
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 602)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 602)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068158.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 22:43:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,892
            CDSs (total)                      :: 3,805
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 87
            rRNAs                             :: 8, 1, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 55
            CDSs (without protein)            :: 55
            Pseudo Genes (ambiguous residues) :: 0 of 55
            Pseudo Genes (frameshifted)       :: 21 of 55
            Pseudo Genes (incomplete)         :: 28 of 55
            Pseudo Genes (internal stop)      :: 16 of 55
            Pseudo Genes (multiple problems)  :: 8 of 55
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..602
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941466-rid12468953.denovo.216"
                     /strain="01A10CD0081"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            206..313
                     /locus_tag="KR231_003856"
     CDS             206..313
                     /locus_tag="KR231_003856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013483530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HBH0006139.1"
                     /translation="MGRHLWNPSYFVATVSENTEEQIRKYINNQKKQVK"
     gene            315..>602
                     /locus_tag="KR231_003857"
     CDS             315..>602
                     /locus_tag="KR231_003857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBH0006140.1"
                     /translation="MVVVEKAYKFRMYPNKKQQELINKTFGCCRFVYNKYLAKRIDVY
                     KNNKETFTYKQCSSDLTNLKKELKWLKEPDKFSLQNALKDLDNAYKKFFKEK"
BASE COUNT          263 a           58 c           94 g          187 t
ORIGIN      
        1 aacttatgtg aacgacaacc tcaaaaatga taaaagttaa gacttacggt tcttatatat
       61 gttatttaaa aataaatata aaaaaacttc aaaatacttg ttttaagtaa ttgtatattt
      121 taatattatg ataggttatg aaaaatggaa gttactcatg gtagaggata tgcatatagt
      181 atgtcaaata tagacagcca gtattatggg gagacatctt tggaatccta gttatttcgt
      241 tgctactgta tcagaaaata cagaggagca gataagaaaa tatattaata atcagaaaaa
      301 acaagtaaag tgaggtggta gtggtggaaa aagcttataa gtttagaatg tatccaaata
      361 aaaaacaaca agagttaatt aacaaaactt ttggatgttg tagatttgta tataataagt
      421 atcttgctaa aagaatagat gtttataaaa acaataaaga aacttttact tataaacagt
      481 gtagttctga tttaaccaat ttaaaaaaag aattaaaatg gcttaaggaa cctgacaaat
      541 tttcattaca aaacgcctta aaagatttag ataatgcata taaaaaattc tttaaagaaa
      601 aa
//
LOCUS       DAEPHU010000206          602 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 01A10CD0081
            SAMN05941466-rid12468953.denovo.217, whole genome shotgun sequence.
ACCESSION   DAEPHU010000206 DAEPHU010000000
VERSION     DAEPHU010000206.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941466
            Sequence Read Archive: SRR6291087
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 602)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 602)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068158.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 22:43:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,892
            CDSs (total)                      :: 3,805
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 87
            rRNAs                             :: 8, 1, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 55
            CDSs (without protein)            :: 55
            Pseudo Genes (ambiguous residues) :: 0 of 55
            Pseudo Genes (frameshifted)       :: 21 of 55
            Pseudo Genes (incomplete)         :: 28 of 55
            Pseudo Genes (internal stop)      :: 16 of 55
            Pseudo Genes (multiple problems)  :: 8 of 55
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..602
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941466-rid12468953.denovo.217"
                     /strain="01A10CD0081"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            316..>602
                     /locus_tag="KR231_003858"
     CDS             316..>602
                     /locus_tag="KR231_003858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBH0006141.1"
                     /translation="MIAVKKAYKFRMYPNKKQQELINKTFGCCRFVYNKYLAKRIDVY
                     KSDKETFTYKQCSSDLTNLKKELKWLKEPDKFSLQNALKDLDNAYKKFFKE"
BASE COUNT          261 a           63 c           94 g          184 t
ORIGIN      
        1 ggaagtgggt agaccttaac ggataatgcc gaaggataag atatagtctg tgcttacatg
       61 aaagtgtaag aagttcataa gagaactgca taggtagtag cgagcttatg tgaacgacaa
      121 cctcaaaaat gataaaagtt aagacttacg gttcttaaat atgttattta aaattaaata
      181 taaaaccttc taaataattg ttttaaataa ttacatttgt taatattatg ataggtggtt
      241 aataaattgt tcaccacagc attatataat atattaaaat cattaaaaag tgtatcaaaa
      301 aacaattaaa gtgaggtgat agcagtgaaa aaagcctata agtttagaat gtatccaaat
      361 aaaaaacaac aagagttaat taacaaaact tttggatgtt gtagatttgt atataataaa
      421 tatcttgcta aaagaataga tgtttataaa agcgataaag aaacttttac ttataaacag
      481 tgtagttctg atttgaccaa tttaaaaaaa gaattaaaat ggcttaagga acctgacaaa
      541 ttttcactac aaaacgcctt aaaagattta gataatgcat ataaaaaatt ctttaaagaa
      601 aa
//
LOCUS       DAEPHU010000207          577 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 01A10CD0081
            SAMN05941466-rid12468953.denovo.218, whole genome shotgun sequence.
ACCESSION   DAEPHU010000207 DAEPHU010000000
VERSION     DAEPHU010000207.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941466
            Sequence Read Archive: SRR6291087
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 577)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 577)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068158.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 22:43:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,892
            CDSs (total)                      :: 3,805
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 87
            rRNAs                             :: 8, 1, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 55
            CDSs (without protein)            :: 55
            Pseudo Genes (ambiguous residues) :: 0 of 55
            Pseudo Genes (frameshifted)       :: 21 of 55
            Pseudo Genes (incomplete)         :: 28 of 55
            Pseudo Genes (internal stop)      :: 16 of 55
            Pseudo Genes (multiple problems)  :: 8 of 55
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..577
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941466-rid12468953.denovo.218"
                     /strain="01A10CD0081"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            <1..>577
                     /locus_tag="KR231_003859"
     rRNA            <1..>577
                     /locus_tag="KR231_003859"
                     /product="16S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00177"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00177"
BASE COUNT          154 a          121 c          190 g          112 t
ORIGIN      
        1 caggatggac ccgcgtctga ttagctagtt ggtaaggtaa cggcttacca aggcgacgat
       61 cagtagccga cctgagaggg tgatcggcca cattggaact gagacacggt ccaaactcct
      121 acgggaggca gcagtgggga atattgcaca atgggcgaaa gcctgatgca gcaacgccgc
      181 gtgagtgatg aaggccttcg ggtcgtaaaa ctctgtcctc aaggaagata atgacggtac
      241 ttgaggagga agccccggct aactacgtgc cagcagccgc ggtaatacgt agggggctag
      301 cgttatccgg atttactggg cgtaaagggt gcgtaggcgg tctttcaagt caggagtgaa
      361 aggctacggc tcaaccgtag taagctcttg aaactgggag acttgagtgc aggagaggag
      421 agtggaattc ctagtgtagc ggtgaaatgc gtagatatta ggaggaacac cagttgcgaa
      481 ggcggctctc tggactgtaa ctgacgctga ggcacgaaag cgtggggagc aaacaggatt
      541 agataccctg gtagtccacg ctgtaaacga tgagtac
//
LOCUS       DAEPHU010000208          533 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 01A10CD0081
            SAMN05941466-rid12468953.denovo.221, whole genome shotgun sequence.
ACCESSION   DAEPHU010000208 DAEPHU010000000
VERSION     DAEPHU010000208.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941466
            Sequence Read Archive: SRR6291087
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 533)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 533)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068158.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 22:43:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,892
            CDSs (total)                      :: 3,805
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 87
            rRNAs                             :: 8, 1, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 55
            CDSs (without protein)            :: 55
            Pseudo Genes (ambiguous residues) :: 0 of 55
            Pseudo Genes (frameshifted)       :: 21 of 55
            Pseudo Genes (incomplete)         :: 28 of 55
            Pseudo Genes (internal stop)      :: 16 of 55
            Pseudo Genes (multiple problems)  :: 8 of 55
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..533
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941466-rid12468953.denovo.221"
                     /strain="01A10CD0081"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            <1..>533
                     /locus_tag="KR231_003860"
     CDS             <1..>533
                     /locus_tag="KR231_003860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage terminase large subunit"
                     /protein_id="HBH0006142.1"
                     /translation="RAMKGSAGSGKSVNVAQDYILKLGDKKYQGANLLVVRKSEATHK
                     YSTYAELTGAINRIYGKQADKYWKTTLNPLEIKSKVTGNSIIFRGVNDAKQREKLKSI
                     NFSKGKLTWVWCEEATELMESDIDILDDRLRGILTNPNLYYQMTFTFNPVSATHWIKR
                     KYFDYKNDDIFTHHSTYL"
BASE COUNT          214 a           69 c           96 g          154 t
ORIGIN      
        1 agagcaatga aaggttcagc agggagtgga aaatctgtta atgtagcaca agactatata
       61 ctaaagttag gagataagaa gtatcaagga gctaatctat tagtagttag aaagtcagaa
      121 gctacacata agtattcaac gtatgcagag cttacaggag ctataaatcg tatttatggt
      181 aaacaagctg ataagtattg gaaaactact ttaaatcctt tagaaattaa gagtaaagtt
      241 actggtaact ctataatttt cagaggagtt aatgatgcaa aacaaagaga aaaattaaaa
      301 tcaattaact tctcgaaagg aaaattaaca tgggtttggt gtgaagaagc tacagaactt
      361 atggaaagtg acatagacat actagatgac cgtttaagag gtattttaac taatcctaac
      421 ctatactatc aaatgacatt tacatttaat ccagtctcag ctactcattg gataaaaaga
      481 aagtattttg actataaaaa tgatgatata tttactcatc atagtactta tct
//
LOCUS       DAEPHU010000209          483 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 01A10CD0081
            SAMN05941466-rid12468953.denovo.224, whole genome shotgun sequence.
ACCESSION   DAEPHU010000209 DAEPHU010000000
VERSION     DAEPHU010000209.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941466
            Sequence Read Archive: SRR6291087
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 483)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068158.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 22:43:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,892
            CDSs (total)                      :: 3,805
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 87
            rRNAs                             :: 8, 1, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 55
            CDSs (without protein)            :: 55
            Pseudo Genes (ambiguous residues) :: 0 of 55
            Pseudo Genes (frameshifted)       :: 21 of 55
            Pseudo Genes (incomplete)         :: 28 of 55
            Pseudo Genes (internal stop)      :: 16 of 55
            Pseudo Genes (multiple problems)  :: 8 of 55
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941466-rid12468953.denovo.224"
                     /strain="01A10CD0081"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
BASE COUNT          205 a           53 c           46 g          179 t
ORIGIN      
        1 tatagccata ataagtatta tttgtattgc atgtttgcta ataagctgat tattagacac
       61 aatagactca aagttattta tggagttgtt tttatagagt ttgcataaag aatagactgg
      121 tgttgtgtat gtaatttgta aaattataca aataaataaa aaaaacatca attttttttg
      181 taaattcctc ataaaaattt cctcccatta aaacacctct attttattag caaataagta
      241 catctcaaaa gtttccattt cttgtaaaat ggatagtttt gaaaagaaaa tattaaaatt
      301 ataatataaa aataaaattt ttcagacaat ttaaacaaaa ataatcacct tttaataaat
      361 aattatatgc caaaataatc caatttattt tctattatac ctatatgaaa tatataaatc
      421 aatagttaag acaatgaata tactacattc tataattata gtagcagaaa attttacaaa
      481 att
//
LOCUS       DAEPHU010000210          431 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 01A10CD0081
            SAMN05941466-rid12468953.denovo.227, whole genome shotgun sequence.
ACCESSION   DAEPHU010000210 DAEPHU010000000
VERSION     DAEPHU010000210.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941466
            Sequence Read Archive: SRR6291087
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 431)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 431)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068158.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 22:43:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,892
            CDSs (total)                      :: 3,805
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 87
            rRNAs                             :: 8, 1, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 55
            CDSs (without protein)            :: 55
            Pseudo Genes (ambiguous residues) :: 0 of 55
            Pseudo Genes (frameshifted)       :: 21 of 55
            Pseudo Genes (incomplete)         :: 28 of 55
            Pseudo Genes (internal stop)      :: 16 of 55
            Pseudo Genes (multiple problems)  :: 8 of 55
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..431
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941466-rid12468953.denovo.227"
                     /strain="01A10CD0081"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            188..304
                     /gene="rrf"
                     /locus_tag="KR231_003861"
     rRNA            188..304
                     /gene="rrf"
                     /locus_tag="KR231_003861"
                     /product="5S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00001"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00001"
     gene            310..398
                     /locus_tag="KR231_003862"
     tRNA            310..398
                     /locus_tag="KR231_003862"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:344..346,aa:Leu,seq:taa)
BASE COUNT          142 a           72 c           92 g          125 t
ORIGIN      
        1 attcattaag atatatgtgc agtttttaga gtgctaactc tatattttta aacttgtcaa
       61 aacttatgga tttttaatag ttttataagg caaaaaatcg aataaaaaaa gtattgacac
      121 aataagacaa agatgttatt ataatacttg tcttagaaaa aaagttaaat gaaaatttag
      181 acaataatct ggttataata gcagagagga tacacctgtt cccattccga acacagaagt
      241 taagctctct agcgctgatg gtacttggtg ggaaactgcc tgggagagta ggacatagcc
      301 aggtgatgtg ccgaagtggc ggaactggca gacgcacagg acttaaaatc ctgcgggact
      361 tacctctcgt accggttcga ttccggtctt cggcaccaca aattattgtg ggccattagc
      421 tcagttggtt a
//
LOCUS       DAEPHU010000211         8946 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 01A10CD0081
            SAMN05941466-rid12468953.guided.114, whole genome shotgun sequence.
ACCESSION   DAEPHU010000211 DAEPHU010000000
VERSION     DAEPHU010000211.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941466
            Sequence Read Archive: SRR6291087
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 8946)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8946)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068158.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 22:43:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,892
            CDSs (total)                      :: 3,805
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 87
            rRNAs                             :: 8, 1, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 55
            CDSs (without protein)            :: 55
            Pseudo Genes (ambiguous residues) :: 0 of 55
            Pseudo Genes (frameshifted)       :: 21 of 55
            Pseudo Genes (incomplete)         :: 28 of 55
            Pseudo Genes (internal stop)      :: 16 of 55
            Pseudo Genes (multiple problems)  :: 8 of 55
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8946
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941466-rid12468953.guided.114"
                     /strain="01A10CD0081"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            complement(197..1012)
                     /locus_tag="KR231_003863"
     CDS             complement(197..1012)
                     /locus_tag="KR231_003863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage integrase family protein"
                     /protein_id="HBH0006143.1"
                     /translation="MVKLSDAKSWAIRMSEDGCAYKSIDNYKRSLKASFFMAIQDDCI
                     RKNPFNFQLSDVLEDTTEPKIALTPEQEMGLLSFMESDKTYCKYYDDVVILLETGLRI
                     SELCGLTLELDMKNKAIMVDHQLLSDTKIGYYVEVPKTTQGKREIPMTERAYQSFERI
                     VERRKNAKAEPIIVDGYQNFLFLKQDGLPKQATHYQSMLRALVKKYNKTHEDKLPKIT
                     PHTFRHTLCTNMANKGMSPNILQYIMGHKNITMTLGYYAHGSFSSSRAEMERL"
     gene            1104..2372
                     /locus_tag="KR231_003864"
                     /pseudo
     CDS             1104..2372
                     /locus_tag="KR231_003864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000331151.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
     gene            2471..3091
                     /locus_tag="KR231_003865"
     CDS             2471..3091
                     /locus_tag="KR231_003865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HBH0006144.1"
                     /translation="MHLIDFMNEDIKKKLVKKTYKKKETILFAEQENEYVILMIDGIA
                     EAFILNVKGNISTIHLYRSGSFFGEMEQFNDGKKPVEIVAFTDCNVYKLHRDDFLNWL
                     RGDFEATKFLIREISSKLVVNAELIEELSSLSVKERLLRCISLHYYRSELNLLTKKQL
                     ASEVNAPIRSINRAINECVQEHLIAYENKRFSVINQREVLKNLPTT"
     gene            3241..3645
                     /locus_tag="KR231_003866"
                     /pseudo
     CDS             3241..3645
                     /locus_tag="KR231_003866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433844.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="oxalate:formate antiporter"
     gene            3770..4696
                     /locus_tag="KR231_003867"
     CDS             3770..4696
                     /locus_tag="KR231_003867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0006145.1"
                     /translation="MSDILSRITNKIGDKNIVDKLSALSKSDLNSLLLEVFDRQANTL
                     TATDILKSYQLNRFTIPSGIDPEEIHALESKLLRKAFNMDIKTIMLSPSAPLGSCSVF
                     GSVDQYNVVSALRGTETLADPSNMLAIIIADKLKRKEENNTIPIHMATTARVIRAQNF
                     VGKGLYSHFGLYCMVSSGIDTGSYTCEKMLLEKHLNYYKDILSEIENVRFSIILRKRN
                     GYKDNDGFFDRMVETIKLIFPNIELSIHNDDVDNNYYKGINFKLSVKQGNETVEIVDG
                     GFVDWTYQMLGNKKERCLISGIGLERFLVAVS"
     gene            4710..5159
                     /locus_tag="KR231_003868"
     CDS             4710..5159
                     /locus_tag="KR231_003868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBH0006146.1"
                     /translation="MELIEWNYAYITDLVEFANDKEIAKNLRDNFPHPYREQNARDFV
                     SFCLATPDVKQLSYAIFYQERAIGSISLTFEEDTSINKNAELGYWLARNYWGKGIATN
                     AVKEICKIAFEKYNLNKIHANVYSYNRGSSKVLEKCGFKIEEYCHNS"
     gene            5519..5926
                     /locus_tag="KR231_003869"
     CDS             5519..5926
                     /locus_tag="KR231_003869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HBH0006147.1"
                     /translation="MVDEKTIEHQFDSFCKTVLRNYARDIYDENKRRNDYLVSLESLS
                     LAELSKLSILDDYDSNYICMVSYDYNIRIEDVLMAQAIGKLTKRKQDIILLSFFLNMT
                     NADIATLMDLAENTIHYHKTNALKELKELMEEH"
     gene            5928..6158
                     /locus_tag="KR231_003870"
     CDS             5928..6158
                     /locus_tag="KR231_003870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBH0006148.1"
                     /translation="MKPTKEVLPFTIILLAVHGDVNAINGILKHFEHYIIRLSQKTLF
                     DEYGNPYIHVEEETKRMLGTKLITAILRFNLS"
     gene            complement(6210..6419)
                     /locus_tag="KR231_003871"
     CDS             complement(6210..6419)
                     /locus_tag="KR231_003871"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH0006149.1"
                     /translation="MVQVTAKQPFQRLFTNHYIVALLIKVMAYSICWLSVSQTYLSTL
                     FSCQRTVGIDLSIKNHNSLWAFIDK"
     gene            6548..6751
                     /locus_tag="KR231_003872"
     CDS             6548..6751
                     /locus_tag="KR231_003872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002262306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excisionase"
                     /protein_id="HBH0006150.1"
                     /translation="MNNTDVPIWEKYTLTIEEASKYFRIGEKKLRKLADENLDSGWVI
                     MNSNRIQIKRKQFEKIVDTLDFI"
     gene            6829..7182
                     /locus_tag="KR231_003873"
     CDS             6829..7182
                     /locus_tag="KR231_003873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="integrase DNA-binding domain-containing protein"
                     /protein_id="HBH0006151.1"
                     /translation="MSTEKRRDNKDRILRTGESQRKDGRYAYKYVYSFGKPQFVYSWK
                     LVPTDKPPKGKRDDISLRDKEKAIQNDLDDSIDTIGKKMTVCQLYAKKNGLRKNIRLN
                     TKKGRHYLMKILNKE"
     gene            7254..7886
                     /locus_tag="KR231_003874"
     CDS             7254..7886
                     /locus_tag="KR231_003874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CatB-related O-acetyltransferase"
                     /protein_id="HBH0006152.1"
                     /translation="MTIPSSNKVYPRSNDYQTVYLKNVITRENIEVGDYTIYNDFYND
                     PRDFEKNNVLYHYPINNDKLIIGKFCSIACNAKFLMTSGNHSMKSKSTYTFPIFYEEW
                     KLDINHITDAWDNKGNIIIGNDVWIGYDSIIMSGVNIGDGAIIGTRAVVTNDVPPYSI
                     VGGVPAKIIKKRFNNDTISKLLEIKWWDWPYKKIQSNIKHIQSGNIDKLV"
     gene            complement(8257..>8946)
                     /locus_tag="KR231_003875"
     CDS             complement(8257..>8946)
                     /locus_tag="KR231_003875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM protein"
                     /protein_id="HBH0006153.1"
                     /translation="KHVERIFLADGDALIIPMEKLRDIILYIKEVFPECERITMYGSP
                     KSIEKKSDDELKELRKLGVKMIYLGLESGSNEVLEDIKKGFSSEQLIKVGRKVKKSGI
                     KLSATVIAGLGGTKKTHQHAVDTGKMLGAISPDYVGVLSLMVEPNTELYDLLKAGEFT
                     ILEDKAVLQEIKEMIKNIDANEKIVFRSNHASNYANLKGVLPDDKQRLIDEIDYYLSN
                     QKLKREEYRRL"
BASE COUNT         3111 a         1357 c         1489 g         2989 t
ORIGIN      
        1 gtatcttttt atttgaaaaa cttatattaa atttgattat cttttcataa gttggtaaat
       61 gtcgatatat cctgtatcta caaggagtat cggcattttc tttttggaag atactttgca
      121 taagttggca tttaaccgta taagaatgcc atcaaaagta gtaaataagt agtaaactct
      181 agtcatacta ctaggattat aaccgttcca tttcagctct cgaagaacta aatgaaccat
      241 gtgcataata gccaagcgtc atagtaatgt ttttatgccc cataatatat tgcaatatat
      301 taggactcat tcctttgtta gccatatttg tacagagtgt atgcctaaag gtatgtggcg
      361 taatctttgg tagcttgtcc tcatgggtct tattatactt cttgactaac gctcttaaca
      421 tgctttgata atgagttgct tgttttggta atccatcttg tttaagaaat aggaagttct
      481 ggtaaccatc aacaatgatt ggttctgctt tagcgttctt acgccgttcc acgatacgtt
      541 caaatgattg ataagctctt tcagtcattg gaatttctcg cttaccctgt gtggtctttg
      601 gaacttctac ataatagcca atcttagtat cactcaacaa ttgatggtct accataatgg
      661 ctttattttt catatccaat tctaaagtca aaccgcataa ttcagaaatg cgtagtcctg
      721 tttctaagag gataacaaca tcatcataat atttacaata agtcttatcg ctctccataa
      781 aggataataa gcccatttcc tgttctggtg ttagagcgat ttttggttct gttgtatctt
      841 ccaaaacatc acttaactga aaattaaatg gattctttct aatacagtcg tcttgaattg
      901 ccatgaaaaa cgacgctttc agtgagcgct tataattgtc aatggattta taagcacacc
      961 catcttcact cattcggata gcccagcttt tagcgtctga taatttaacc atatcaatgc
     1021 tttttgcacc tagtgggtca ttgatagtat ctatattttg atttataatt tatacatttt
     1081 tttaaaaaca gacttttaac tgtaaagaat ctatgtataa acttagctat gttgtccgtg
     1141 tatctacaaa ggatcttgac gagctaaaaa ggcgttgtga tgaagtcaaa gacttttacg
     1201 acgacttatc actcaagctc gtgcgtccct ttggggatat gttgggattg catggcgaat
     1261 ttattcctgt cagcaaacgt tacatcaatg attatattca atatgtcact tcggattttt
     1321 tggctggact tggttttgga gcgacacaaa cccttggcga acatgaggat atctatcttg
     1381 gctacaatct ggacactgga aagaatgtct atctaaaacc tgcccttgct agtcaatggg
     1441 taaagggttc tattaccaat gtgttagcgt ctgcgtttat cggttcattg ggtggtggta
     1501 aattattcag taacaatatg cttgtttact atgcggtact attcggcgga caggcggtca
     1561 tagttgaccc taaagcagaa cgcggcaaat ggaaagaaac gctaccagaa atagcccatg
     1621 agataaacat tgtcaattta accagtaatg atgaaaacaa aggattgctt gacccttacg
     1681 tcattttgag ccgtaaaaat gattctgaaa gtttagcgat tgatatccta acattccttg
     1741 ctggtatctc cagtcgtgac agtgataagt tcccagtgct tagaaaagca atccgcaatg
     1801 taacccaaag tgaacagcga gggttattac ttgtcattga tgaattacga aaagaagata
     1861 cttctatcag taacagcata gccgaccata tcgaaagttt tgtagactat gattttgcac
     1921 atctactgtt tggtgacgga aatgtgaagc agtctatcag cttggagaaa cagctgaata
     1981 ttattcaagt tgctgacctc gtattgccag atgccaacac tagctttgaa gaatatacaa
     2041 caatagaact tcttagtgtt gctatgttga ttgttattag tacctttgca ttagacttta
     2101 ttcatactga ccgctctagc ttcaagatag ttgaccttga cgaagcatgg tcttttttgc
     2161 aggtggcaca aggtaaaacg ctatctatga aactggttag agcatcgcaa gattcacagg
     2221 acaaacgaat tgaacgtttg aagaattatc tgactgaaaa cctacaacag ttgaatactg
     2281 aaatggttcg ctcatatatt cctactagtt ctattgtcaa cagctttctc agtttgagct
     2341 tactttgcag aaaaatgaca actggaaaat aataatggaa tagtttctat gtaaatatat
     2401 ttttactatc ttacctaact aattgaaaga tgatataatt taatcaaaga tttggtaagg
     2461 agggatgaat atgcatttaa ttgattttat gaatgaagat attaaaaaga agcttgttaa
     2521 aaaaacgtat aaaaagaaag agactattct ttttgctgag caagaaaatg aatatgtaat
     2581 tcttatgatt gacggtattg cagaagcatt catcttaaat gtgaaaggaa acatctcaac
     2641 tattcatctt tatagaagtg gtagtttttt tggagaaatg gaacaattta atgatgggaa
     2701 aaaacccgtt gaaattgtcg ctttcacaga ttgtaatgta tataaacttc atagagatga
     2761 ttttttaaac tggttaaggg gagattttga agctacaaaa tttctgattc gagaaatatc
     2821 tagtaaatta gttgtaaatg ctgaattaat tgaagaatta tcatctttaa gtgttaaaga
     2881 acgacttctg aggtgtatat ccttacacta ttatagaagt gaattaaatc tgcttaccaa
     2941 aaaacagctt gctagcgaag taaacgctcc aattagaagc attaatcgtg ctataaatga
     3001 atgtgtacaa gaacatctaa ttgcttatga aaacaaaaga tttagtgtaa ttaatcagcg
     3061 agaggtatta aagaatcttc ctacaacata agtataattt caaaaaagta ttgaataata
     3121 attattcaat gcttttttat ttcgggtcaa gtgacctatt tttttttatt ttttcattat
     3181 ataatactcc tatgcataat tatgttggat tgatagctaa taaaagaaag tgagaggtgt
     3241 tatactaaaa aagaagcata cttcccaact ccagacttac agtggattga agatagattt
     3301 tggatttggg ttcattacgc ttgcactaag attggacgta gagaactatt tgaaacaatt
     3361 gattttttat cttttttaag acaatcagta cttgccccat taatacagct tctcttaggt
     3421 aaattacctc gtggagttag aaaaattgaa ttggacgcac cccaatatat tgaagcatta
     3481 gaaaagacgg ttgctaacca tgaatataaa agctgtgtta atgcattgca ggctactatc
     3541 aacctgtatc ttgagttaag agaggaatta tcacaaagtc ctattgtccg aaaggttgaa
     3601 gctgaaaggg ttgcattaca gtattttcaa gatttaatca aataaaccca aagtaaaaaa
     3661 atattgaata gtaaatattc agtgtttttt catttttggt caaatgacct agattagttg
     3721 ttgtaaccat tctataatta ttttgaaagt aacagtatgg aggataacta tgagtgatat
     3781 tttaagtaga attacaaata aaattgggga taagaatata gttgataagt tatcagctct
     3841 atcaaaatca gatttgaact cacttctatt agaagtgttt gatagacaag caaatacttt
     3901 aactgcaact gatattctaa agtcatacca actaaataga tttactatcc ctagcggtat
     3961 agatccagaa gaaattcatg ctttggagtc aaaattattg agaaaagcat tcaatatgga
     4021 tatcaagacg attatgcttt ctccctctgc tccattaggt agctgtagcg tttttggctc
     4081 cgtagatcaa tataatgtag taagtgctct acgagggaca gaaacacttg cagacccctc
     4141 aaatatgttg gcaataatta ttgctgataa attaaaaaga aaagaagaaa ataataccat
     4201 acctatccac atggctacta ctgctagggt aataagagca caaaattttg taggtaaagg
     4261 tttatattca cattttggct tatattgtat ggtttcatct ggtatagata cagggtctta
     4321 cacttgtgaa aaaatgttgt tagaaaagca cttaaactat tataaagata tattaagtga
     4381 aatagaaaat gttcgtttct ctattattct acgcaaaaga aacggataca aagataatga
     4441 cggatttttc gacagaatgg ttgaaactat caaacttatt tttcctaata tagagttatc
     4501 aattcataat gatgatgttg ataataatta ttataaaggt atcaatttca aattatcggt
     4561 caaacaagga aatgaaaccg ttgaaatagt tgacggtgga tttgttgact ggacttatca
     4621 aatgcttgga aataaaaaag aacgctgttt gataagtggt attggcttag aaagatttct
     4681 tgtagctgtt tcataaaagg agaagaaaaa tggaacttat agagtggaat tatgcttata
     4741 ttaccgattt agttgagttt gcgaatgata aagaaattgc aaagaatctt cgtgacaact
     4801 tcccccaccc ttatagggag caaaacgcta gagattttgt tagtttttgt ttggcaactc
     4861 cagatgttaa acaacttagc tatgctattt tttatcaaga aagggctatt ggaagtatca
     4921 gcctaacatt tgaagaagat acctctatta ataaaaatgc tgaattaggt tactggcttg
     4981 ctaggaacta ttggggcaaa gggatagcaa caaatgcagt aaaagaaata tgcaaaattg
     5041 cctttgaaaa atacaacctt aacaaaattc atgctaatgt atattcctac aatagagggt
     5101 caagtaaagt attggaaaaa tgtggtttta agattgaaga atactgtcac aattcataat
     5161 aaagaataga aacatgattg attgccatgt atatagttta attcgaccgc aatagcattt
     5221 attagaatta acctactttt taataacaga ataagttttt cccctctatt aatttcttat
     5281 gcatctttgt atttttatga aaagctagcc aatgcatatt tccatacatc aatatggtgg
     5341 tggcttacaa ccaatataaa ttaaatacgt tttaaagaat acacattttt gccctatagg
     5401 cagagtgtgt atttttttct cttttttttg aaatttatcg aagatttaac gccctcccac
     5461 cgtgatagga gtaagcaagg ttatttaact ccttgcgatg gaaagagggt gaaatcttat
     5521 ggttgatgaa aagacaattg aacatcaatt cgacagtttc tgtaaaacag ttttgcgtaa
     5581 ctatgctaga gatatttatg acgaaaataa acgcagaaat gattatttgg tatctctcga
     5641 atctttgtca cttgcagaat taagtaaatt gagtatttta gatgattatg attctaacta
     5701 catctgtatg gtttcttacg actacaacat acgaattgaa gatgtattaa tggcacaagc
     5761 aatcggaaaa cttacaaaaa gaaaacaaga tataattcta ctttcattct ttctcaacat
     5821 gacaaatgct gacatagcaa cattgatgga tttagcagaa aataccatac attatcacaa
     5881 aacaaatgca ctaaaagagt tgaaagaact catggaggaa cattgaaatg aaacctacta
     5941 aagaagtatt accttttaca attattttac ttgctgtaca tggcgatgta aatgcaataa
     6001 acggaatact taaacatttt gaacactata tcattcgtct ttcacagaaa actttatttg
     6061 atgaatacgg aaatccctat attcatgtag aagaagaaac aaagcgaatg ctaggaacaa
     6121 aactaatcac tgctattttg agatttaatt tgtcttaatc tcgccctctc tccatgtatc
     6181 aagctatttg gtacatggag aatcactaat tatttgtcta taaaagccca taagctattg
     6241 tgatttttta tagacaaatc aatgccgact gttctttgac aactgaataa agtagataga
     6301 tacgtttgtg atacagatag ccaacaaata ctatacgcca tgaccttaat caagagagct
     6361 actatatagt gatttgtgaa taacctttgg aacggttgtt ttgccgtaac ctgtaccaca
     6421 gtataatgat acacctgtat gacacggttc tgcccataag aatgggattg gttaaaatac
     6481 caatggagct taccaaagcc atctatctac ttctgaacta cgaacataga aaggagtgat
     6541 acattctatg aacaatactg atgtacctat ttgggaaaaa tataccttga cgattgaaga
     6601 agcgtcaaaa tactttcgta ttggagagaa aaaattacgt aaacttgctg atgaaaacct
     6661 tgattctggc tgggtcatta tgaatagcaa tcgcattcaa ataaagagaa aacaatttga
     6721 gaaaatcgtt gatacacttg actttatcta atgaaattga gccttatatg ttataatatt
     6781 catatgacgt atcaagctca attcggttat tgagaggagc ttcttatcat gtcaactgaa
     6841 aaaagacgag ataataaaga tagaatttta agaactggag agagccagag aaaagatgga
     6901 agatacgcat ataagtatgt atattcattt ggtaaaccac aatttgttta ctcttggaaa
     6961 cttgtaccta ctgataaacc cccaaaggga aaacgtgatg atatatcatt aagggataag
     7021 gaaaaagcaa tacaaaatga ccttgatgat agcattgaca ctattggtaa gaaaatgaca
     7081 gtttgtcagt tatacgctaa aaagaatgga ctaagaaaga atatccgact taacactaaa
     7141 aaaggacgcc attatcttat gaagattctt aacaaggagt gattctgtga agagatgtat
     7201 tgtagtagtg gaatagtcaa aaacataata tatattaaag gagagattta aatatgacta
     7261 ttccaagttc aaataaggta tatccaagaa gtaatgatta tcaaactgta tatcttaaaa
     7321 atgtaataac aagggaaaat atagaagttg gagattacac aatatataat gacttttata
     7381 atgacccaag agattttgag aaaaacaatg tattgtatca ttaccctata aacaatgata
     7441 aattaataat tggtaagttt tgctcaatag catgtaatgc aaaatttcta atgactagtg
     7501 gaaatcactc aatgaaatca aaatccacat atacttttcc catcttttat gaagaatgga
     7561 aactcgatat caaccatata acggacgctt gggacaataa gggtaacatt ataattggaa
     7621 atgatgtgtg gataggttat gattctataa ttatgtcagg tgtaaatatt ggtgatggtg
     7681 caattattgg aacaagagca gtagttacta atgacgttcc accgtattct attgttggag
     7741 gagtacctgc aaaaattata aaaaagagat ttaataatga tacaatttca aaattattag
     7801 aaattaaatg gtgggattgg ccatataaaa aaattcaatc aaacattaag catattcaat
     7861 caggaaatat tgataaatta gtttaatatt ttataattta tttatattaa actttacttt
     7921 aataatcatt ttataagagc tttttcaaaa tttgtatatt attttaatat atataaattt
     7981 aatacaacat taaataaaat aaaaagtaaa gttacttaat aaaaagttac tttacttttt
     8041 attatttaaa ttcctgtttt tattataata ggtaaaattc tattaaacta gttcacattt
     8101 tcattattat tgatatatta tatatgaata taccattttg ttttttaata aaaaaatcat
     8161 gctacatcaa tagtaagcaa ctattaatgt agcatgattt tttgtatcta aataatctta
     8221 gtatttacct atcaatatag attgatatat caaaaactat agtcttctat attcttctct
     8281 ttttagcttt tggttactta gatagtaatc aatttcatca attagacgtt gtttatcatc
     8341 aggtaataca ccttttaaat tagcataatt tgatgcatga ttacttctaa atacaatttt
     8401 ttcattagca tctatattct ttatcatctc tttaatttct tgtaacacag ccttatcctc
     8461 tagtattgta aactctcctg ccttaagtaa atcgtaaagt tcagtattag gttctaccat
     8521 taaactaagt acacccacat aatctggtga aattgctcct aacatttttc ctgtatcaac
     8581 tgcatgctga tgtgtttttt tagttcctcc aagacctgct attacagtgg ctgataattt
     8641 aatcccactt tttttaactt ttctaccaac ttttattaat tgttcactac taaaaccttt
     8701 cttaatatct tctaatactt cattgcttcc actttcaagc cctagataaa tcattttaac
     8761 accaagtttt cttaattctt taagttcatc atcagatttt ttctctatag atttaggaga
     8821 gccgtacata gtaattcttt cacactctgg aaaaacttct tttatatata agataatatc
     8881 tcttaatttc tccattggta ttatcaatgc atctccatct gctaagaata ttctttctac
     8941 atgctt
//
LOCUS       DAEPHU010000212         5893 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 01A10CD0081
            SAMN05941466-rid12468953.guided.139, whole genome shotgun sequence.
ACCESSION   DAEPHU010000212 DAEPHU010000000
VERSION     DAEPHU010000212.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941466
            Sequence Read Archive: SRR6291087
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 5893)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5893)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068158.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 22:43:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,892
            CDSs (total)                      :: 3,805
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 87
            rRNAs                             :: 8, 1, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 55
            CDSs (without protein)            :: 55
            Pseudo Genes (ambiguous residues) :: 0 of 55
            Pseudo Genes (frameshifted)       :: 21 of 55
            Pseudo Genes (incomplete)         :: 28 of 55
            Pseudo Genes (internal stop)      :: 16 of 55
            Pseudo Genes (multiple problems)  :: 8 of 55
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5893
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941466-rid12468953.guided.139"
                     /strain="01A10CD0081"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            <1..160
                     /locus_tag="KR231_003876"
     CDS             <1..160
                     /locus_tag="KR231_003876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase family
                     protein"
                     /protein_id="HBH0006154.1"
                     /translation="KIEDKEKIIEIFYVPIHTKEEVRISIPEQCVYQISGNNKDGFIV
                     TFWRNRKD"
     gene            178..2316
                     /gene="vanT"
                     /locus_tag="KR231_003877"
     CDS             178..2316
                     /gene="vanT"
                     /locus_tag="KR231_003877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_021418922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine racemase VanT catalytic subunit"
                     /protein_id="HBH0006155.1"
                     /translation="MIRNKSYAGLDYFRIIAALLIIAIHTSPLLSYSKMADFVLTSII
                     ARIAVPFFFMLSGFFLISTYNYNCNKLKSFLKNVLFIYGIAIVIYIPLNIYTGYFSMN
                     NLVPNIIKDIVFDGTLYHLWYLPASIIGASIAYFLVKKLGLKYSLVITIVIYVIGMFG
                     DSYYGFLEKIPLLKNLYGYIFEVSDYTRNGIFFAPVFFILGGIISNKSNYMSTKNSLI
                     GFLISFLLMLCEGMFLHKLGVQRHDSMYIMLLPCMYFLFTALTFLKGSRARLLRTSSL
                     IIYIIHPMMIVVIRMFSKIFGIQTVLVDNSLIHYIVVSIASFIASIIIILILKPLKKD
                     LKGEHKVNTNRAWIEIDLNNLEHNVKMIQKAMPEDCELMAVVKANAYGHSAFEVATCA
                     NQIGVKAFAVATIDEGIDLRRYGILGEILILGYTNPIRAKELHKYNLTQSVIDLNHAI
                     SLNKQKYNIKSHIKIDTGMHRLGFDVNDVRSILKAFKLKYLDICGIFTHLCVSDSLKD
                     EDVDFTNKQIECFYKLIDFLLKKGIKIPKVHIQSSYGFFNYPNLKCNYVRIGIALYGI
                     LSFPNDTTKLQLDLRPVLSLKSQVILIRKIQKDDSFGYGRVFIASRDSVIAILSIGYA
                     DGIPRNLSCGKSYVIINGCRAAIVGRICMDQLAVDITDIPNVEVGNTAIIIGRDNLSE
                     LSVSEVANNSCSISNELLSRVGRRLNVIKK"
     gene            2630..3250
                     /locus_tag="KR231_003878"
     CDS             2630..3250
                     /locus_tag="KR231_003878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TVP38/TMEM64 family protein"
                     /protein_id="HBH0006156.1"
                     /translation="MQYIQELLDLTQNYWVLATIIGLLSAFIESFIPALPLVAIVTAN
                     AAIQGLFIGCLLSWIGSGLGTTSLFLLISRFNDSKLFNKLRNSKTEKAISWMDKQGFK
                     LLFIAYACPFMPGCLVTIASAFGKKDLKDFVPAMLAGKFVMFIVISYVASDIEGFITS
                     PLKIASFILLVFLSWKIGNRVNKNLENHNYDFHHKKHHNDKDDKMI"
     gene            complement(3416..3952)
                     /locus_tag="KR231_003879"
     CDS             complement(3416..3952)
                     /locus_tag="KR231_003879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent hydrolase"
                     /protein_id="HBH0006157.1"
                     /translation="MIKETHERGGYIFALLILPFINNLYLVKYDIAYKIVLIIIYIYF
                     AYLGSLFPDIDMRGSYISKKFMLIYKLFGSRFRHRGFTHSLIALLLIYSFFKSLTIFT
                     NNNIVFSCLSSGFIIGYLSHLCLDLITKEGIELFYPITINISLLPIKTNSKTEKFISK
                     LLNFIVIFLIGYQFYILL"
     gene            complement(4065..4739)
                     /locus_tag="KR231_003880"
     CDS             complement(4065..4739)
                     /locus_tag="KR231_003880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000094049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="superoxide dismutase"
                     /protein_id="HBH0006158.1"
                     /translation="MSLFIISQCITSFAFTPENNKFKVKPLPYAYDALEPYIDKETMK
                     LHHDKHYQAYVDKLNAALEKYPELYNYSLCELLQNLDSLPKDIATTVRNNAGGAYNHK
                     FFFDIMTPEKTIPSESLKEAIDRDFGSFEKFKQEFQKSALDVFGSGWAWLVATKDGKL
                     SIMTTPNQDSPVSKNLTPIIGLDVWEHAYYLKYQNRRNEYIDNWFNVVNWNGALENYK
                     NLKSQD"
     gene            4942..>5893
                     /locus_tag="KR231_003881"
     CDS             4942..>5893
                     /locus_tag="KR231_003881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine synthetase B"
                     /protein_id="HBH0006159.1"
                     /translation="MDGNISIYYKGDISKKEDIKFKIKESVNNTRLSSRIEYKDEEKT
                     FDFERFNVIDAIYGNKPFEKDGKVIVFNGNIYNYHEIKEELIKKGHNFTTNDDIEVLL
                     ASYIEFGKNCVHKIKGMFNFIIYDRENESIFGARDLFGIKPLYYINKENAIIFSSEYK
                     FLLEYMKNLNINERSLQSYFSFQYVLPEDTMIQGIRLIPAGHYFRVENGILSLKRYNK
                     LEFRSSTKFFYTKNHLGNRDVNEDDIRNIVVDSIVTHMEEEKEIGTFLSGGIDSSIIT
                     TVASQINPNIKSFSAGFSVKGYSELEVAKKTADKLGIENIQ"
BASE COUNT         2208 a          661 c          912 g         2112 t
ORIGIN      
        1 aaaaatagaa gataaagaaa aaattataga aatcttttat gtgcctattc atactaaaga
       61 agaagtgaga atctctatac ctgaacaatg tgtatatcaa atatcgggta acaataagga
      121 tggttttatt gtgacatttt ggagaaatag aaaggactaa gaaatggagg aacaagaatg
      181 attaggaata aatcttatgc agggcttgat tattttagga ttatagctgc attacttata
      241 attgcaattc atacatctcc attattatca tatagtaaaa tggctgactt tgtgttaact
      301 agtataattg ctcgtattgc tgtgccattc ttttttatgc tatcaggctt ttttctaatt
      361 tcaacatata attataattg taataaactg aaatcttttc taaaaaatgt attatttatt
      421 tacgggatag ctattgtaat ttatattccc ttaaatattt acactggata tttttccatg
      481 aataatttag tgcccaatat tattaaggac attgtatttg atgggacttt atatcattta
      541 tggtatcttc ctgcatcaat tattggtgca agtattgcat actttcttgt aaaaaaacta
      601 ggtttaaagt actcactagt aatcactatt gttatttatg taattggtat gtttggtgat
      661 agttattatg gttttttaga aaaaatacca ctattaaaga atttatatgg gtatattttt
      721 gaagtatcag attatacacg aaatggtata ttttttgcac ctgtattttt catacttggt
      781 ggaataatat ctaataaatc taattatatg tcaactaaaa atagcttgat tggatttctt
      841 atatcattct tacttatgtt atgtgaggga atgtttttac ataaactagg ggtacagcgt
      901 catgatagca tgtatattat gttattgcca tgtatgtatt tcttatttac agccttaaca
      961 tttttgaaag gttctcgagc taggttattg cgaacatcat cattaattat ttatattata
     1021 catcctatga tgattgttgt tattcgtatg ttttctaaaa tattcggaat acaaactgtc
     1081 ttggttgaca atagccttat tcattatata gtggtaagta tagcatcttt tatagcttct
     1141 ataattatta tattgattct taaacctcta aaaaaagact tgaaaggaga acataaggta
     1201 aataccaata gagcttggat tgaaattgat ttaaataatt tggaacataa tgtaaagatg
     1261 atacaaaaag ctatgccaga agattgtgaa ttgatggcag ttgtaaaagc taatgcctat
     1321 ggtcatagtg cttttgaagt agcgacttgt gcaaaccaaa taggtgtaaa agcatttgca
     1381 gtagcaacaa tagatgaggg gattgattta cgtcgatatg gaatactagg agaaatattg
     1441 attcttggat atactaaccc aataagggca aaggaacttc ataaatacaa tcttacacag
     1501 agtgttattg accttaatca tgctatctct ttaaacaaac agaaatacaa cataaaatca
     1561 cacattaaaa ttgatacagg tatgcacaga ctgggttttg atgttaatga tgtgaggtca
     1621 attttaaagg catttaaatt aaaatactta gatatatgtg gcatatttac acacttgtgt
     1681 gtttcagata gtctgaaaga tgaagatgta gactttacaa ataaacaaat tgaatgtttt
     1741 tataagttaa ttgattttct gttaaaaaaa ggtataaaaa ttcctaaagt acatattcaa
     1801 agtagttatg gtttttttaa ttatcccaat cttaagtgta attatgtaag aattggaatt
     1861 gcattatacg ggatattaag ttttccaaat gatacgacta aattgcaact tgatttacga
     1921 cctgttttat ccttaaaatc acaagtaatt cttattagaa aaatacaaaa agatgatagt
     1981 tttggatatg gaagagtctt tattgcaagc agagatagcg taattgctat attatctatt
     2041 ggctatgccg atggtatacc tagaaattta tcctgtggaa aaagttacgt aataataaat
     2101 ggttgtagag cagcaatagt gggtcgaatt tgcatggacc aacttgctgt tgatattaca
     2161 gatataccta atgtagaagt tggtaatacg gcaataataa taggaagaga taatttatct
     2221 gaattatctg tttctgaagt tgcaaataac tcatgtagta tatcgaatga attattgagc
     2281 agagtaggaa gaaggttaaa tgttataaag aagtaactca attaaatagt aatatttgtt
     2341 gtactgtgta atttatttta ctctgactag acatttttag taatattatg tctaatatat
     2401 attttttata acttacatga caatttaagt tataaaaagg tgatgtttca gatttttatt
     2461 ttgaaacatc accttttttg ttataatata taataaaata attatacctt aactgtaaac
     2521 ttatatagat tatttacttt ttaatattag attcattttt tgagattggt atataataaa
     2581 catatagagt atataataat agttaaagtt aaaaaagggg aaaagcaata tgcagtatat
     2641 acaagaacta cttgatttga ctcaaaatta ttgggtgtta gccacaataa tcggcttatt
     2701 aagtgcattt atagaaagct ttataccagc cttaccactt gttgctatag ttacagcaaa
     2761 tgctgcaata caaggattat ttattggatg tttgttatca tggattggct caggacttgg
     2821 gacaacttca ttattcttat taataagcag atttaatgat agtaagcttt ttaataagtt
     2881 gagaaatagt aaaactgaaa aagcaataag ttggatggat aaacagggat ttaagttatt
     2941 atttatagcg tatgcctgtc catttatgcc cggttgttta gttactatcg catcagcttt
     3001 tggtaaaaaa gatttaaaag attttgtgcc agcaatgttg gcaggaaaat ttgtaatgtt
     3061 tatagttata agttacgtgg caagtgatat agaaggtttt ataacaagtc ctttaaagat
     3121 agcatcattt atattattgg tgtttttgtc atggaagatt ggaaatagag taaataaaaa
     3181 tcttgaaaat cataattatg atttccatca taaaaaacat cacaatgata aagatgataa
     3241 aatgatttag cttgtacgaa ataaaacgta tcttaaaatg atttagtact aaattatttt
     3301 aagatacgtt ttattttttg tattaaggta caaaattttt agttcttttg taaactaaaa
     3361 tatataaaac ttatttatac ttagttcaaa atattgttat ttattttttc tacaactata
     3421 ataaaatata aaattgatat ccaatcaaaa aaataactat gaaatttaat agcttagata
     3481 tgaatttttc tgtttttgag ttagttttta taggtagtaa agaaatgttt atagtaatgg
     3541 gataaaacaa ttcaatacct tctttagtaa taaggtcaag acacaagtga gatagatatc
     3601 ctattataaa cccactggac aaacatgaga aaactatatt attgttagtg aagattgtca
     3661 gagatttaaa aaaactataa ataagtaata aggcaattag actgtgagta aaccctctat
     3721 gtctaaacct acttccaaat aatttgtata ttaacataaa ttttttactt atgtaagaac
     3781 ctctcatatc tatatctgga aataaagaac ctaaatatgc aaaataaata taaattataa
     3841 ttaatactat tttatatgca atatcgtatt taactaggta cagattgttt ataaagggga
     3901 gtatcaaaag tgcgaatata taacctcccc tttcatgtgt ttcttttatc atataaaaat
     3961 cctcctgaat cgtcactata aacattatat tggtaaattt agactatctt ttattatatt
     4021 atatagcaaa cataagtttt tttcaaaagg attttaatat ttaattaatc ttgagatttt
     4081 aaatttttgt aattttctaa agcaccattc caatttacta cattaaacca gttgtcaatg
     4141 tattcatttc ttctattttg atattttaaa tagtaagcat gctcccaaac atcaagtcct
     4201 attataggag ttaggttttt acttacaggg ctatcctgat ttggagtagt cataatagat
     4261 aatttcccat ctttagtagc tacaagccaa gcccaaccag aaccaaagac atctaaagca
     4321 gatttttgga actcttgctt aaatttttca aaagaaccaa agtctctatc aatagcttct
     4381 tttaaagatt cagaaggtat ggttttttct ggcgtcatta tatcaaaaaa gaatttatga
     4441 ttataagctc cacctgcatt atttcttaca gttgtagcaa tatctttagg taaagaatct
     4501 aaattttgca ataattcaca taaagaataa ttataaagct caggatattt ttcaagagca
     4561 gcatttaatt tatcaacata agcttgataa tgcttatcat gatgcagttt cattgtttct
     4621 ttatctatat aaggttcaag tgcatcatat gcataaggta atggtttaac cttaaatttg
     4681 ttattttcag gtgtaaaagc aaatgaagtt atgcactgtg agattataaa taaagacata
     4741 ataactggta ttaatatttt tttcttcata aaaatcacct cctaatatag tatttctaga
     4801 aataaaaaaa atatgaaata ttaacagata atttataaga atttaatagc aatttcattt
     4861 taaattgaat aagttttaaa gccaaagaca aaactatgaa atatagaata agactaaagg
     4921 acagaaagga attttgatta tatggacggc aatatttcaa tttattataa aggtgatata
     4981 tctaaaaaag aagatattaa atttaaaata aaagaatctg taaataatac aagactttct
     5041 agtagaatag agtataagga tgaggaaaaa acttttgatt ttgaaagatt taatgtaatt
     5101 gatgctattt atggaaataa accatttgaa aaagatggaa aagttattgt ttttaatgga
     5161 aatatatata actatcatga aataaaagaa gaattaatta aaaaaggaca caattttact
     5221 acaaatgatg atattgaagt cttattggca tcttatatag aatttggtaa gaattgtgta
     5281 cataagatta aaggaatgtt caactttata atctatgata gagaaaatga aagtatattt
     5341 ggagcaagag atttatttgg gataaaacca ctctattata taaataagga aaatgcaata
     5401 attttttcct cagagtataa gtttttactt gaatatatga aaaatttaaa tataaatgaa
     5461 agaagcttac aaagttattt ttcatttcaa tatgtacttc ctgaagatac tatgatacaa
     5521 ggaataaggc tgataccagc aggtcactat tttagggtag aaaatggtat actatcttta
     5581 aagagatata ataaacttga gtttagaagt agtacaaaat ttttttatac taaaaatcac
     5641 ttaggcaata gagatgtgaa cgaggatgat ataagaaata tagtagtaga ttcaatagta
     5701 actcatatgg aagaggagaa agaaattgga acatttctgt ctggtggaat agattcatct
     5761 attataacta ctgtggcttc acaaattaat ccaaatataa aatctttttc tgcaggcttt
     5821 agtgtcaaag gatatagtga attagaagta gcaaagaaaa cagctgataa gttaggtata
     5881 gaaaatatcc aga
//
LOCUS       DAEPHU010000213         4017 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 01A10CD0081
            SAMN05941466-rid12468953.guided.155, whole genome shotgun sequence.
ACCESSION   DAEPHU010000213 DAEPHU010000000
VERSION     DAEPHU010000213.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941466
            Sequence Read Archive: SRR6291087
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 4017)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4017)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068158.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 22:43:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,892
            CDSs (total)                      :: 3,805
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 87
            rRNAs                             :: 8, 1, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 55
            CDSs (without protein)            :: 55
            Pseudo Genes (ambiguous residues) :: 0 of 55
            Pseudo Genes (frameshifted)       :: 21 of 55
            Pseudo Genes (incomplete)         :: 28 of 55
            Pseudo Genes (internal stop)      :: 16 of 55
            Pseudo Genes (multiple problems)  :: 8 of 55
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4017
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941466-rid12468953.guided.155"
                     /strain="01A10CD0081"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            278..1231
                     /gene="blaCDD"
                     /locus_tag="KR231_003882"
     CDS             278..1231
                     /gene="blaCDD"
                     /locus_tag="KR231_003882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434692.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDD family class D beta-lactamase"
                     /protein_id="HBH0006160.1"
                     /translation="MKRKKNFIWIAILLVGVVMVMYYVGKKHNDINQKTDKNYIKSEL
                     NKSELNKSKIENNDKNKKEKINMVDYSDCFEGISGGAIFYNTKNKEYNIYNKELIETR
                     RSPCSTFKIVSTLIGLEKGVINSKESVMGYDGTEYPNKNWNKNLSLEEAFKESCVWYY
                     KKLIDKVDAKSVQNILDDLKYGNCDISEWEGDLKNGKGHLNGFWLESSLQISPKEQVQ
                     TMAKIFEGDTNFKKEHINILRDIMKIDINDKNINVYGKTGTGFDEKNKRVDAWFVGML
                     EREGDTYYFAIKSDDSNKEITGPKVKEIAINIIKKYYSVRE"
     gene            1575..2258
                     /locus_tag="KR231_003883"
     CDS             1575..2258
                     /locus_tag="KR231_003883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH0006161.1"
                     /translation="MEILKCENLTKIYGSNQTRVTALNNVNLSVQKGDFVSIVGASGS
                     GKSTLLHLLGGVDRPTSGKIYVEDTEISSLKEEALAVFRRRKVGLIYQFYNLIPTLDV
                     RKNILLPMLLDKRKVDEDRFSEIVSILGLSDRLNHLPSQLSGGQQQRVSIARSLIYRP
                     AILLADEPTGNLDRKNSEEIVDLLNLSNKRFNQTILLITHDEKIALEANRIVTMEDGV
                     IVSEKVVKK"
     gene            2255..>4017
                     /locus_tag="KR231_003884"
     CDS             2255..>4017
                     /locus_tag="KR231_003884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HBH0006162.1"
                     /translation="MNILQEYTLDFVRRNKRSSIAIMLAILLTTTMMSSLCGLLYTMW
                     TDFIRLSIEKEGNWHGELFDYTYGSDLPLIENFSSVDDVMVKGQWYVGKINDEKRDYI
                     IYRNATSEYWNSMPEKDTIIEGRRPNNANEIALSKQYFENNPSVKIGDKITLPIGYRI
                     LNGKPLEPIAPKSKGESFKKISEATLTIVGKVDVSTSSVIPAYTALGYLDKTSIKPND
                     SITVYLRFKNIRDTYKELPKLAKSLGWKTNEYGKYNLKYNSNYLLKMLVFSPEQKASM
                     SSISKFSTPIMYLTIAIFTVAVFVMVIYNAFSLSANARLTQLGILSSVGASPKQIKRS
                     VVFEGFLLTIIPLPIGLFLGWLLCNRLIVYVNSVNYHTDVPEVVFTYGIPAFLPAVLL
                     TIVTVWISALIPARKVSKISPIEAIRQGDSVKIKKSHKYSLGKIFGIEGELASNALRA
                     RKKSYRTATISLTLSFLLLTCFLHIIANQEGAKAVYGSDNYKDQRDIAVYLENSEPIE
                     SAFIEKLDNTEGVKSSLYYQKMSASTWLTEKDASKELAKNGGFKSIVSSKKYSPIERD
                     GKFRIISNIIGLDDKSFTEYC"
BASE COUNT         1557 a          458 c          689 g         1313 t
ORIGIN      
        1 attgtaatat ttaaatatta caatagtaag ttttaaatgt ggaatcaatt attatatcac
       61 aaattaaaag gaggacagga tgttattaat agttacctaa ttatcttcgc aataggttta
      121 atcaacataa ttgtactagg tgaagaaaat ataagagata cagctattca tttagtcttg
      181 tttcttataa gtagaaccta gattggagta tattacaaat aatgtctact attttaatag
      241 taggttataa atttaaatat gggagatgat ataaattatg aaaagaaaaa agaattttat
      301 ttggatagct atcttattgg ttggtgtagt tatggtaatg tattatgtag ggaaaaaaca
      361 taacgatata aatcaaaaaa ctgataagaa ttatataaaa tctgaattaa ataagtctga
      421 attaaataaa tccaaaattg aaaacaatga taaaaacaaa aaagaaaaaa ttaatatggt
      481 tgactatagt gattgttttg aaggtattag tggaggagct attttttata atactaaaaa
      541 taaagaatat aatatatata acaaagaatt aattgaaaca agaaggtcac catgttctac
      601 ttttaaaata gtttcaactt taattggttt agaaaaaggg gtaataaact caaaagaatc
      661 agttatggga tatgatggta cagagtatcc aaataaaaat tggaataaaa atcttagttt
      721 agaagaggca tttaaggagt cttgtgtttg gtattacaaa aaattgatag ataaagttga
      781 tgctaaatct gtccaaaaca ttttagatga tttaaagtat gggaattgcg atattagcga
      841 atgggaaggc gatttaaaaa atggaaaggg acatttaaat ggattttggt tagaatcttc
      901 attacaaata tctccaaaag aacaagtgca aacaatggca aaaatatttg agggagatac
      961 aaactttaaa aaagagcata ttaatatttt aagagatatt atgaaaatag atataaatga
     1021 taaaaacata aatgtatatg gaaaaactgg aacaggattt gatgaaaaaa ataaacgtgt
     1081 ggatgcatgg tttgttggta tgctagagcg tgaaggtgac acctattatt ttgctattaa
     1141 atcagatgat tccaataaag aaattacagg gccaaaggta aaggaaattg caattaatat
     1201 aattaagaaa tattatagtg taagggaata aacttaattt tatttgtaaa tattatttac
     1261 ctatagtctg taatatttat taaataattt tactaaattg agtctatata gagcaaaact
     1321 cctttagtac ataaaatact tgctattgat tattaaattg aatacctata gatttaaagt
     1381 taataccttt taaagactat gtaatatatt aaaagtataa ataaaatata ttgcatagtt
     1441 tttgttttat attataattt taaataatgt gcaaaaacta aacaatattt ttaatagtaa
     1501 tttatatttg tattcatgtc actataatgt cattttaggt tgctaaaatt taaccataaa
     1561 ggagatgatt gtatatggaa atattaaaat gtgaaaatct cacaaaaata tatggttcaa
     1621 atcaaaccag agtgacagcc cttaataatg taaatttatc agttcaaaaa ggtgattttg
     1681 tatccattgt aggagcatct ggttctggca aatctacatt gttacatctg cttgggggag
     1741 tagatagacc tacatctgga aagatttatg ttgaagatac agaaatatca agtttaaagg
     1801 aagaagctct tgcagttttt agacgtagaa aagtaggtct tatttatcaa ttttataatc
     1861 ttatacctac ccttgatgtt agaaaaaata tattattacc catgttactt gataaaagaa
     1921 aggtggatga ggatagattc tctgagattg tatctatatt gggattatct gatagattaa
     1981 accatcttcc aagtcaactt tcaggtggac aacaacaaag ggtatctata gctagaagtt
     2041 taatctatag accagctatt ttattagcag atgagccaac tggtaatctt gatagaaaaa
     2101 attcagaaga aattgtagac ttgttaaact tatcaaataa acgatttaat cagacaatac
     2161 ttcttattac tcatgatgag aaaatagcac tagaggcaaa tcgtattgta actatggaag
     2221 atggagtgat tgtctctgaa aaggtggtga agaaatgaat attcttcaag aatacacctt
     2281 agactttgta cgacgcaata aacgtagtag tatagctata atgttagcta tattacttac
     2341 tacaaccatg atgtcttctt tgtgtggact gttgtatacc atgtggacag attttataag
     2401 actttcaatt gagaaagaag gtaactggca tggtgaattg tttgactata cttatggaag
     2461 tgacttacca ttaattgaaa atttttcttc agttgatgat gtaatggtaa aaggacaatg
     2521 gtatgtaggc aaaattaatg atgagaaaag agattatata atttatagaa atgctacatc
     2581 agagtattgg aattctatgc cagaaaagga tactataata gagggtcgtc gaccaaataa
     2641 tgctaatgaa attgcattat caaaacaata ttttgagaat aatccaagtg taaaaattgg
     2701 tgataaaatt actctcccaa taggatatag aatcttaaat ggaaagcctc ttgaacccat
     2761 agccccaaaa tcgaaagggg aaagttttaa aaaaatttca gaggctacat tgacaatagt
     2821 aggaaaggta gatgtttcta cttcatcagt aatacctgca tatacagctc ttggatatct
     2881 tgataaaaca agtataaaac ctaatgatag tataactgtg tacttgcgat ttaaaaatat
     2941 aagagacacg tataaggaac ttccaaaact tgctaaatca ttgggatgga agactaatga
     3001 atatggaaaa tacaatctta aatacaatag taattatctt ttaaagatgt tagtcttttc
     3061 accagaacag aaagcatcta tgagtagtat atcaaaattt tcaactccta ttatgtatct
     3121 tacaatagca atttttacag tagccgtgtt tgtaatggtg atttacaacg cgttttcact
     3181 gtctgcaaat gctagactta ctcagttagg gatattatct agtgttggtg catcaccaaa
     3241 acaaattaaa aggtctgtag tgtttgaagg ctttttactg acaattatac cattaccaat
     3301 aggtttattt ttaggatggt tattgtgtaa taggcttata gtttatgtta attcagttaa
     3361 ttatcatact gatgttccag aagtggtatt tacttatggt attcctgctt ttctgccagc
     3421 agttttactt acaatagtaa cagtctggat ttctgcactt ataccagcac gaaaagtatc
     3481 aaagatatct cctatagaag caatacgaca aggagatagt gttaaaatca aaaagtcgca
     3541 taaatattca ttaggaaaga tatttggaat agaaggagaa cttgcatcaa acgcactacg
     3601 tgctcgtaaa aaatcttatc gtactgcaac aatatcttta acattatctt ttttattact
     3661 tacatgtttt ttgcatataa ttgcaaatca agaaggagca aaagctgttt atggaagtga
     3721 taattataag gaccaaagag atatagcagt ttatttggaa aatagtgaac ctatagagtc
     3781 tgctttcatt gaaaaattag ataatacaga aggtgtaaaa agttcactat attatcaaaa
     3841 aatgtctgct tccacttggc tgactgaaaa agatgcatca aaagaacttg cgaaaaatgg
     3901 aggatttaaa agtatagttt catctaaaaa atactctcct atagaacgtg atggcaagtt
     3961 tcgtataatt tcaaatataa ttgggcttga tgataagagt tttacagaat attgtag
//
LOCUS       DAEPHU010000214         1837 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 01A10CD0081
            SAMN05941466-rid12468953.guided.182, whole genome shotgun sequence.
ACCESSION   DAEPHU010000214 DAEPHU010000000
VERSION     DAEPHU010000214.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941466
            Sequence Read Archive: SRR6291087
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1837)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1837)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068158.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 22:43:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,892
            CDSs (total)                      :: 3,805
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 87
            rRNAs                             :: 8, 1, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 55
            CDSs (without protein)            :: 55
            Pseudo Genes (ambiguous residues) :: 0 of 55
            Pseudo Genes (frameshifted)       :: 21 of 55
            Pseudo Genes (incomplete)         :: 28 of 55
            Pseudo Genes (internal stop)      :: 16 of 55
            Pseudo Genes (multiple problems)  :: 8 of 55
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1837
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941466-rid12468953.guided.182"
                     /strain="01A10CD0081"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            95..1195
                     /gene="vanG"
                     /locus_tag="KR231_003885"
     CDS             95..1195
                     /gene="vanG"
                     /locus_tag="KR231_003885"
                     /EC_number="6.3.2.35"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_021418924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--D-serine ligase VanG"
                     /protein_id="HBH0006163.1"
                     /translation="MNNKKIAVIFGGNSTEYDVSLQSAFAVLENLNTEKYDIIPIGIT
                     REGNWYHYIGDYNNIQNNTWFERDTDIIPVIVSQNRVKNGIIEFLIPDAVSQNHIPNS
                     AIESCENDIKYTKLDFVFPVLHGKNGEDGTVQGLFELAGIQVIGCGTLSSALCMDKDK
                     SHKLVHSEGIKVPKSILLKYSDKFNVAELSKDLTYPLFIKPVRAGSSFGISKIYKKEE
                     LQVAVDLAFEHDNEVIIEENIDGFEVGCAVLGNNDLLVGRVDEIELSKGFFDYTEKYT
                     LKSSKIHMPARIDLDCEKRIQETAKIIYRTLGCSGFARVDMFLTPSGEIIFNEVNTIP
                     GFTSHSRYPNMMKGIGLSFEEILDKIIEVYIK"
     gene            1192..>1837
                     /locus_tag="KR231_003886"
     CDS             1192..>1837
                     /locus_tag="KR231_003886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M15 family metallopeptidase"
                     /protein_id="HBH0006164.1"
                     /translation="MMNNILLDKNKEDKMTNTILLTKDKVYDGNLILVNAFLPVKTSE
                     DIDLIPVDTRFPSILMKREATNILQNILKSICGINEIVPVSGYRTAEEQQDIYSSSLR
                     DNGKDFTKKFVALPNHSEHQTGLAIDLGLKKEVIDFICPEFPYNGICNEFRKAALHYG
                     FIERYQCKKEEITGISQEPWHFRYVGYPHSEIINKMNLALEEYIEYIKRFSYTNC"
BASE COUNT          689 a          205 c          340 g          603 t
ORIGIN      
        1 agtgaaggtt gattggattt gaaatagaaa aagtatttta acatgtttct gtagattgta
       61 taaaaataaa taaatcaaca aaggagaatc aaagatgaat aataaaaaaa ttgcagttat
      121 atttggtgga aactcaacag aatatgatgt atcattacaa tcagcttttg cagtacttga
      181 gaatttgaat acggaaaaat atgatattat accaattgga attacaaggg agggtaattg
      241 gtatcattat attggagatt ataataatat ccagaataac acttggtttg aaagggatac
      301 tgatataatt ccagttattg tttcgcagaa ccgtgtcaaa aatggtatta ttgaattttt
      361 aattcctgat gctgtttctc agaatcatat tccaaatagt gctattgaat catgtgaaaa
      421 tgatattaaa tacactaaac ttgattttgt gtttcctgta ctgcatggaa aaaatggaga
      481 agatggaaca gtgcaggggt tatttgaatt ggcaggtata caggttattg gatgtggtac
      541 tctttcttca gcattatgta tggacaaaga caaatcacat aaacttgttc attcagaagg
      601 tattaaagta ccaaaatcaa tattactaaa atactcagat aaatttaatg tggctgaact
      661 gtcaaaagac ttaacttatc cattatttat aaaacctgtg cgtgcaggtt catcatttgg
      721 tattagtaaa atttataaaa aagaagagtt acaagtagca gtagacttgg cttttgaaca
      781 tgataatgaa gtaataattg aggaaaatat tgatggtttt gaggtagggt gtgcagtttt
      841 aggaaacaat gacttacttg ttggaagagt agatgaaata gaattgtcaa aaggattttt
      901 tgattataca gaaaaatata cattgaaaag ttcaaaaatt catatgccag ctagaattga
      961 tttggattgt gagaaaagaa tacaagagac agcaaaaatt atttatagaa ctcttggatg
     1021 ttctggattt gctagagtag atatgttttt aactccatct ggtgaaatta tttttaatga
     1081 agtcaataca attcctggct ttacttctca tagtcgttat ccaaatatga tgaaaggtat
     1141 tggactgtct tttgaagaaa tattggacaa gataattgag gtgtacataa aatgatgaat
     1201 aatattttat tagataaaaa taaagaagat aaaatgacaa atactatctt attgactaaa
     1261 gataaagttt atgatgggaa tctaattcta gtaaatgctt ttttaccagt taaaacatct
     1321 gaagatatag atttaattcc tgtagataca aggtttccaa gtattcttat gaaacgtgaa
     1381 gctacaaaca ttttacaaaa tattttaaaa agtatatgtg gaataaatga aatagtacct
     1441 gtaagtggat atcgtactgc agaggaacaa caagatatat attcaagttc tctgcgtgac
     1501 aatggaaaag actttactaa aaagtttgta gcacttccaa atcacagtga acatcagaca
     1561 gggcttgcta ttgatttagg gttaaagaaa gaagttatag attttatctg ccctgaattt
     1621 ccttataatg gtatttgtaa tgagtttcgt aaggcagcac tacattatgg ttttatagag
     1681 cgttatcagt gtaaaaaaga agaaataaca ggaatatctc aagaaccatg gcattttcgt
     1741 tatgtgggat atccgcattc tgagattatc aataaaatga atctcgctct tgaagaatat
     1801 atagaatata ttaagagatt ttcgtataca aattgtt
//
LOCUS       DAEPHU010000215         1439 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 01A10CD0081
            SAMN05941466-rid12468953.guided.188, whole genome shotgun sequence.
ACCESSION   DAEPHU010000215 DAEPHU010000000
VERSION     DAEPHU010000215.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941466
            Sequence Read Archive: SRR6291087
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1439)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1439)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068158.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 22:43:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,892
            CDSs (total)                      :: 3,805
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 87
            rRNAs                             :: 8, 1, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 55
            CDSs (without protein)            :: 55
            Pseudo Genes (ambiguous residues) :: 0 of 55
            Pseudo Genes (frameshifted)       :: 21 of 55
            Pseudo Genes (incomplete)         :: 28 of 55
            Pseudo Genes (internal stop)      :: 16 of 55
            Pseudo Genes (multiple problems)  :: 8 of 55
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1439
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941466-rid12468953.guided.188"
                     /strain="01A10CD0081"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            18..734
                     /locus_tag="KR231_003887"
     CDS             18..734
                     /locus_tag="KR231_003887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBH0006165.1"
                     /translation="MNSYNILVVEDEKEIADAIEIYLLNQGYNVFKGYNGLEGLKVIE
                     NQEIHLAIVDIMMPKMDGITLTMKLRENYNFPVIMLSAKSEEVDKIMGLNIGADDYVT
                     KPFKPLELLARVNSQLRRYTKYLNMVGNKEQKVESDDSVFAIGGLELNENTKEVSIDG
                     KYIKTTPIEFKILSLLMRNAGRVFSADEIYERVWNENAVNTDTVMVHVRNIREKIEID
                     PKNPKYLKVVWGVGYKIEKI"
     gene            709..>1439
                     /locus_tag="KR231_003888"
     CDS             709..>1439
                     /locus_tag="KR231_003888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HBH0006166.1"
                     /translation="MDTKLKKFKDKYIVTIIVFILMLSASLGMISQYSTIQASAKGGA
                     ENPFEQESFVDSIYKGSYVLYHNMKEEQEGKMIQPSKLFINEETMNYIKNVSKEKDTY
                     DGSETYYTDDSINADFNENFENWEHFIKASGKNLKYYLVDKESNFEFFNDNKELGVLD
                     TTKNDASKENSNENQSKNTEMNDEERQKQITDIKENYRFYVVMNFDKDGKVNIVDSYG
                     VNQKIINQMLLSKAREDLMDTSLGG"
BASE COUNT          623 a          125 c          273 g          418 t
ORIGIN      
        1 atataaagga gattagaatg aattcatata atattttggt agtagaagat gaaaaggaga
       61 tagcagatgc tatagaaata tatctattaa atcaaggata taatgttttt aagggataca
      121 atggattaga aggtcttaag gttatagaaa accaagaaat acatttagct atagttgata
      181 taatgatgcc taaaatggat ggtataacac ttacaatgaa gcttagagaa aactataatt
      241 ttccagtaat aatgctatct gcaaaatcag aagaagttga caaaataatg gggcttaata
      301 taggagcaga cgattatgta acaaaacctt ttaagccatt agaactattg gctagagtta
      361 attcacaact tagaaggtac actaagtatc taaacatggt tggaaataaa gagcaaaagg
      421 tagaaagtga cgatagtgtg tttgcaatag gcggattaga attaaatgaa aatacaaaag
      481 aagttagtat tgatggaaag tatataaaaa caactcctat agaatttaaa atactaagtt
      541 tacttatgag aaatgcagga agagtttttt ctgctgatga aatatatgaa agagtttgga
      601 atgagaatgc tgtaaataca gatacagtta tggtacatgt gaggaatata agggaaaaga
      661 tagaaattga cccaaaaaat cctaaatatt taaaggtggt gtggggtgtt ggatacaaaa
      721 ttgaaaaaat ttaaagataa atatatagtt actattatag tttttatact tatgttatca
      781 gcatcattag gtatgattag tcaatattct actatacaag caagtgctaa aggtggagca
      841 gagaatccat ttgaacagga aagctttgta gatagtatat ataaaggaag ttatgtttta
      901 tatcataata tgaaggaaga acaagaaggt aagatgatac aaccatcaaa gctatttatc
      961 aatgaagaaa ctatgaacta tataaaaaat gtaagtaaag aaaaagatac ttatgatggt
     1021 tcagaaactt attatacaga tgatagtatt aatgcagatt ttaatgaaaa ctttgaaaat
     1081 tgggagcatt tcattaaagc gtcaggaaag aatttaaagt actatttagt tgataaagaa
     1141 agcaattttg aattttttaa tgataataaa gaattaggag tacttgatac aacaaaaaat
     1201 gatgcttcaa aagaaaattc taatgaaaat cagtcaaaaa atacagaaat gaatgatgag
     1261 gaaagacaaa agcagattac agatataaaa gaaaactata gattctacgt tgtaatgaat
     1321 tttgataaag atggaaaagt aaatattgtg gattcttatg gagtaaatca aaaaattatt
     1381 aatcaaatgt tgttatctaa agcaagagaa gatttaatgg atacaagttt aggaggaaa
//
LOCUS       DAEPHU010000216         1439 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 01A10CD0081
            SAMN05941466-rid12468953.guided.189, whole genome shotgun sequence.
ACCESSION   DAEPHU010000216 DAEPHU010000000
VERSION     DAEPHU010000216.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941466
            Sequence Read Archive: SRR6291087
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1439)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1439)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068158.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 22:43:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,892
            CDSs (total)                      :: 3,805
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 87
            rRNAs                             :: 8, 1, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 55
            CDSs (without protein)            :: 55
            Pseudo Genes (ambiguous residues) :: 0 of 55
            Pseudo Genes (frameshifted)       :: 21 of 55
            Pseudo Genes (incomplete)         :: 28 of 55
            Pseudo Genes (internal stop)      :: 16 of 55
            Pseudo Genes (multiple problems)  :: 8 of 55
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1439
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941466-rid12468953.guided.189"
                     /strain="01A10CD0081"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            18..734
                     /locus_tag="KR231_003889"
     CDS             18..734
                     /locus_tag="KR231_003889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBH0006167.1"
                     /translation="MNSYNILVVEDEKEIADAIEIYLLNQGYNVFKGYNGLEGLKVIE
                     NQEIHLAIVDIMMPKMDGITLTMKLRENYNFPVIMLSAKSEEVDKIMGLNIGADDYVT
                     KPFKPLELLARVNSQLRRYTKYLNMVGNKEQKVESDDSVFAIGGLELNENTKEVSIDG
                     KYIKTTPIEFKILSLLMRNAGRVFSADEIYERVWNENAVNTDTVMVHVRNIREKIEID
                     PKNPKYLKVVWGVGYKIEKI"
     gene            709..>1439
                     /locus_tag="KR231_003890"
     CDS             709..>1439
                     /locus_tag="KR231_003890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HBH0006168.1"
                     /translation="MDTKLKKFKDKYIVTIIVFILMLSASLGMISQYSTIQASAKGGA
                     ENPFEQESFVDSIYKGSYVLYHNMKEEQEGKMIQPSKLFINEETMNYIKNVSKEKDTY
                     DGSETYYTDDSINADFNENFENWEHFIKASGKNLKYYLVDKESNFEFFNDNKELGVLD
                     TTKNDASKENSNENQSKNTEMNDEERQKQITDIKENYRFYVVMNFDKDGKVNIVDSYG
                     VNQKIINQMLLSKAREDLMDTSLGG"
BASE COUNT          622 a          125 c          274 g          418 t
ORIGIN      
        1 atataaagga gattagaatg aattcatata atattttggt ggtagaagat gaaaaggaga
       61 tagcagatgc tatagaaata tatctattaa atcaaggata taatgttttt aagggataca
      121 atggattaga aggtcttaag gttatagaaa accaagaaat acatttagct atagttgata
      181 taatgatgcc taaaatggat ggtataacac ttacaatgaa gcttagagaa aactataatt
      241 ttccagtaat aatgctatct gcaaaatcag aagaagttga caaaataatg gggcttaata
      301 taggagcaga cgattatgta acaaaacctt ttaagccatt agaactattg gctagagtta
      361 attcacaact tagaaggtac actaagtatc taaacatggt tggaaataaa gagcaaaagg
      421 tagaaagtga cgatagtgtg tttgcaatag gcggattaga attaaatgaa aatacaaaag
      481 aagttagtat tgatggaaag tatataaaaa caactcctat agaatttaaa atactaagtt
      541 tacttatgag aaatgcagga agagtttttt ctgctgatga aatatatgaa agagtttgga
      601 atgagaatgc tgtaaataca gatacagtta tggtacatgt gaggaatata agggaaaaga
      661 tagaaattga cccaaaaaat cctaaatatt taaaggtggt gtggggtgtt ggatacaaaa
      721 ttgaaaaaat ttaaagataa atatatagtt actattatag tttttatact tatgttatca
      781 gcatcattag gtatgattag tcaatattct actatacaag caagtgctaa aggtggagca
      841 gagaatccat ttgaacagga aagctttgta gatagtatat ataaaggaag ttatgtttta
      901 tatcataata tgaaggaaga acaagaaggt aagatgatac aaccatcaaa gctatttatc
      961 aatgaagaaa ctatgaacta tataaaaaat gtaagtaaag aaaaagatac ttatgatggt
     1021 tcagaaactt attatacaga tgatagtatt aatgcagatt ttaatgaaaa ctttgaaaat
     1081 tgggagcatt tcattaaagc gtcaggaaag aatttaaagt actatttagt tgataaagaa
     1141 agcaattttg aattttttaa tgataataaa gaattaggag tacttgatac aacaaaaaat
     1201 gatgcttcaa aagaaaattc taatgaaaat cagtcaaaaa atacagaaat gaatgatgag
     1261 gaaagacaaa agcagattac agatataaaa gaaaactata gattctacgt tgtaatgaat
     1321 tttgataaag atggaaaagt aaatattgtg gattcttatg gagtaaatca aaaaattatt
     1381 aatcaaatgt tgttatctaa agcaagagaa gatttaatgg atacaagttt aggaggaaa
//
LOCUS       DAEPHU010000217         1259 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 01A10CD0081
            SAMN05941466-rid12468953.guided.198, whole genome shotgun sequence.
ACCESSION   DAEPHU010000217 DAEPHU010000000
VERSION     DAEPHU010000217.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941466
            Sequence Read Archive: SRR6291087
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1259)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1259)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068158.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 22:43:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,892
            CDSs (total)                      :: 3,805
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 87
            rRNAs                             :: 8, 1, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 55
            CDSs (without protein)            :: 55
            Pseudo Genes (ambiguous residues) :: 0 of 55
            Pseudo Genes (frameshifted)       :: 21 of 55
            Pseudo Genes (incomplete)         :: 28 of 55
            Pseudo Genes (internal stop)      :: 16 of 55
            Pseudo Genes (multiple problems)  :: 8 of 55
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1259
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941466-rid12468953.guided.198"
                     /strain="01A10CD0081"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            12..1094
                     /locus_tag="KR231_003891"
     CDS             12..1094
                     /locus_tag="KR231_003891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HBH0006169.1"
                     /translation="MRTALMAFIAIIFIWILYSFILYGKFSIWIVSFFENAFRMEYKA
                     ALNLYQQIFRNSMELFMILAMVIVFFIIFRVYLNWFTKYFSEINQGIDSLIKEDVGEV
                     ALSPELLAIEKKINSIKHILEQRKFETQMAEQRKNELIVYLAHDLKTPLTSVIGYLTL
                     LRDESQISEELRKKYLSISLDKAERLEDLINEFFEITRFNLSNISLEYSTVSLTRMLE
                     QLTYEFKPTLMSKNLKYTLNVTPNMMIRCDVNKMQRVFDNLLRNAVYYSFEDTTIEIT
                     AVQEDDYIKLKFINHSNTIPEEKLERIFEQFYRLDTSRNSNSGRAGLGLAIAKEIVEL
                     HNGTITAHSENNIITFKVIIPIVGNL"
BASE COUNT          463 a          148 c          214 g          434 t
ORIGIN      
        1 ataaaatttt tatgagaaca gctttaatgg catttatagc cattattttc atatggattt
       61 tatattcttt tatattgtat ggtaagtttt ctatctggat agtatcattc tttgaaaatg
      121 cttttcgtat ggaatataaa gctgcattga atttatatca gcagattttc cgtaatagta
      181 tggagctctt catgatacta gctatggtga ttgtgttttt tataatattc cgtgtttatt
      241 taaattggtt tacaaaatat tttagtgaaa taaatcaagg tattgactct cttatcaaag
      301 aagatgttgg agaagtggct ttatctccag agttattggc aatagaaaag aaaataaact
      361 caattaaaca tatacttgaa caacgtaaat ttgagacaca aatggcagaa caacgtaaga
      421 atgaacttat tgtttatctt gcacatgatt taaaaacacc acttacatca gttatagggt
      481 atctgacact acttcgagat gaaagtcaga tttctgaaga actgcgaaaa aaatatttat
      541 ctatttcgtt ggataaggca gagcgtcttg aagatttaat taatgaattc tttgaaatta
      601 caaggtttaa tttatcaaat atatcacttg aatacagtac agtaagctta actcgtatgc
      661 ttgaacaact aacatatgag tttaaaccta ctttgatgag taagaattta aaatatacac
      721 tgaatgttac accaaatatg atgataaggt gtgatgttaa taaaatgcaa cgtgtatttg
      781 ataacttatt acgaaatgct gtttattata gttttgaaga tactactatt gaaataacag
      841 ctgtacagga ggatgattat ataaagctta aatttataaa tcatagcaat acgattccag
      901 aggaaaaact tgagcgtatt tttgaacaat tttacaggtt ggatacatct cgtaattcaa
      961 acagtggtag agctgggttg ggacttgcta tagctaaaga aatagtggag cttcataacg
     1021 ggacaataac agctcatagc gagaacaata taattacctt taaggttatt attccgattg
     1081 taggaaattt gtaagaattt aagtataaaa aaataggaaa ttctttagga taaataaata
     1141 aagagcactc ttgttattga tataattact gtatcaaaac aagagtgctt ttattttgat
     1201 acagtaatta tatcaataga aaaatgtgaa aatatattat gtggaacaga tgcaattgt
//
LOCUS       DAEPHU010000218          774 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain 01A10CD0081
            SAMN05941466-rid12468953.guided.206, whole genome shotgun sequence.
ACCESSION   DAEPHU010000218 DAEPHU010000000
VERSION     DAEPHU010000218.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05941466
            Sequence Read Archive: SRR6291087
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 774)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 774)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001068158.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001068158.1
            Genome Coverage       :: 101x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/12/2021 22:43:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,892
            CDSs (total)                      :: 3,805
            Genes (coding)                    :: 3,750
            CDSs (with protein)               :: 3,750
            Genes (RNA)                       :: 87
            rRNAs                             :: 8, 1, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 8 (5S)
            partial rRNAs                     :: 1, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 55
            CDSs (without protein)            :: 55
            Pseudo Genes (ambiguous residues) :: 0 of 55
            Pseudo Genes (frameshifted)       :: 21 of 55
            Pseudo Genes (incomplete)         :: 28 of 55
            Pseudo Genes (internal stop)      :: 16 of 55
            Pseudo Genes (multiple problems)  :: 8 of 55
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..774
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05941466-rid12468953.guided.206"
                     /strain="01A10CD0081"
                     /isolation_source="stool sample (feces)"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Canada"
                     /collection_date="2010"
                     /collected_by="Canadian Nosocomial Infection Surveillance
                     Program"
     gene            36..737
                     /locus_tag="KR231_003892"
     CDS             36..737
                     /locus_tag="KR231_003892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_021418928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanG-Cd-type vancomycin resistance DNA-binding
                     response regulator VanR"
                     /protein_id="HBH0006170.1"
                     /translation="MNENILIVDDEKEIADLIEVYLKNEGFTVYKFYTGKEALECIES
                     KNLDMAILDIMLPDIDGFHICQKIREKYYYPIIMLTAKIEDIDKIMGLTIGADDYITK
                     PFNPLEVVARVKTQLRRYMRYNNSYEQQSIIVNEYDIKGLIINKETHKCSLFGKEVAL
                     TPIEFSILWYLCEHQGKVVPSEELFEAVWGEKYLDNNNTVMAHIGRLREKIHEPSKNP
                     KFIKTVWGVGYTIEK"
BASE COUNT          306 a           81 c          142 g          245 t
ORIGIN      
        1 atgacctcga taataaggag agtgaaaaat aatctatgaa cgaaaatatt ttgattgtgg
       61 atgatgaaaa agaaatagca gatttaattg aagtatattt aaaaaatgaa ggttttacag
      121 tatacaagtt ttatacaggt aaggaagctc tagaatgtat tgaatctaaa aatttggata
      181 tggctatttt agatattatg cttcctgata ttgatggatt tcatatttgc cagaaaattc
      241 gagaaaaata ctattatcct atcattatgt taacagctaa aattgaagat atagacaaga
      301 taatgggttt aaccataggt gctgatgatt atataacaaa gccatttaac cctttggaag
      361 ttgttgcaag agtaaagaca caattaagaa gatatatgcg atataataat tcttatgaac
      421 aacagtcgat aattgttaat gagtatgata ttaaaggatt gattatcaat aaagaaacac
      481 ataaatgtag tttatttggg aaagaagtag cattaacacc gattgaattt tctattcttt
      541 ggtatttatg tgaacatcaa ggaaaagtgg ttccttctga agaattgttt gaagctgtat
      601 ggggagaaaa atatcttgat aataataaca cagttatggc tcatataggg cgattacgtg
      661 aaaaaattca tgaaccttct aaaaacccga aatttataaa aactgtatgg ggagtaggtt
      721 atacaattga aaagtaaaaa tattaaagtc aatcctgact ttactcaagt gaga
//
